# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- EthD PF07110.11 OAG33762.1 - 7.9e-14 52.6 0.0 1e-13 52.2 0.0 1.2 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 OAG33762.1 - 1.8e-06 28.4 0.0 2.8e-06 27.8 0.0 1.3 1 1 0 1 1 1 1 Methylmuconolactone methyl-isomerase RT_RNaseH PF17917.1 OAG33763.1 - 5.8e-30 103.7 0.0 6.8e-30 103.5 0.0 1.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 OAG33763.1 - 3.8e-21 75.0 0.0 7.9e-21 74.0 0.0 1.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Ferric_reduct PF01794.19 OAG33764.1 - 1.3e-20 73.8 13.4 1.3e-20 73.8 13.4 2.2 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 OAG33764.1 - 5.3e-16 58.7 0.0 1.4e-15 57.3 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 OAG33764.1 - 5.5e-05 23.3 0.0 9.6e-05 22.6 0.0 1.5 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Chordopox_L2 PF05803.12 OAG33764.1 - 0.12 12.2 0.1 0.28 11.1 0.1 1.5 1 0 0 1 1 1 0 Chordopoxvirus L2 protein FAD_binding_6 PF00970.24 OAG33764.1 - 0.17 12.3 0.0 0.32 11.4 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain DUF1270 PF06900.11 OAG33764.1 - 1.4 9.4 5.4 0.43 11.0 1.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1270) DDE_3 PF13358.6 OAG33765.1 - 1.7e-09 37.5 0.0 2.8e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_33 PF13592.6 OAG33765.1 - 2e-09 36.9 0.0 3.6e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn helix Arg_repressor PF01316.21 OAG33765.1 - 0.003 17.3 0.1 0.0044 16.7 0.1 1.2 1 0 0 1 1 1 1 Arginine repressor, DNA binding domain HTH_Tnp_Tc3_2 PF01498.18 OAG33765.1 - 0.025 14.8 0.0 0.043 14.1 0.0 1.4 1 0 0 1 1 1 0 Transposase Glyco_hydro_1 PF00232.18 OAG33767.1 - 1.9e-157 524.3 0.0 2.5e-157 523.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 peroxidase PF00141.23 OAG33768.1 - 1.5e-25 90.3 0.0 2.8e-25 89.4 0.0 1.4 1 0 0 1 1 1 1 Peroxidase Attacin_N PF03768.15 OAG33768.1 - 0.022 14.9 0.2 0.11 12.6 0.2 2.4 1 0 0 1 1 1 0 Attacin, N-terminal region Cu_amine_oxid PF01179.20 OAG33769.1 - 7.8e-159 529.0 0.0 9.7e-159 528.7 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.16 OAG33769.1 - 2.9e-07 30.6 0.0 5.9e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.16 OAG33769.1 - 4.4e-06 27.0 0.0 1.1e-05 25.7 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain TMEM234 PF10639.9 OAG33769.1 - 0.15 12.1 0.0 0.28 11.2 0.0 1.3 1 0 0 1 1 1 0 Putative transmembrane family 234 LapA_dom PF06305.11 OAG33770.1 - 2.8 7.8 5.5 6.6 6.6 0.1 2.7 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain DUF3040 PF11239.8 OAG33771.1 - 0.047 14.0 1.2 1 9.6 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) GDPD PF03009.17 OAG33774.1 - 2e-11 44.1 0.0 2.6e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family MFS_1 PF07690.16 OAG33776.1 - 1e-35 123.4 31.9 1e-35 123.4 31.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG33776.1 - 8.3e-17 61.2 2.1 8.3e-17 61.2 2.1 2.6 2 1 1 3 3 3 1 Sugar (and other) transporter PTR2 PF00854.21 OAG33776.1 - 0.00049 19.0 0.4 0.0014 17.6 0.4 1.7 1 0 0 1 1 1 1 POT family BT1 PF03092.16 OAG33776.1 - 0.0014 16.9 0.7 0.042 12.1 0.1 2.5 1 1 1 2 2 2 2 BT1 family DUF4044 PF13253.6 OAG33776.1 - 0.29 10.7 1.5 1.1 8.9 1.5 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Ribosomal_S30 PF04758.14 OAG33777.1 - 0.28 11.4 2.4 0.33 11.2 1.2 1.8 2 0 0 2 2 2 0 Ribosomal protein S30 Ras PF00071.22 OAG33778.1 - 6.6e-43 146.1 0.0 2.8e-37 127.8 0.0 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 OAG33778.1 - 1.5e-29 102.6 0.0 3.7e-29 101.4 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAG33778.1 - 1.6e-10 40.7 0.0 3e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OAG33778.1 - 2.5e-06 27.2 0.1 1.5e-05 24.6 0.1 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OAG33778.1 - 0.00057 19.3 0.0 0.00077 18.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OAG33778.1 - 0.00067 19.7 0.0 0.0011 19.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OAG33778.1 - 0.0015 18.5 0.1 0.059 13.3 0.0 2.3 1 1 1 2 2 2 1 RsgA GTPase AAA_30 PF13604.6 OAG33778.1 - 0.0035 17.1 0.1 0.0069 16.1 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OAG33778.1 - 0.009 16.4 0.0 0.025 15.0 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 OAG33778.1 - 0.024 14.8 0.1 0.049 13.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 OAG33778.1 - 0.036 14.3 0.0 0.088 13.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain SRPRB PF09439.10 OAG33778.1 - 0.039 13.4 0.0 0.067 12.6 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 OAG33778.1 - 0.051 13.8 0.0 0.099 12.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 OAG33778.1 - 0.057 13.9 0.0 0.13 12.8 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_7 PF12775.7 OAG33778.1 - 0.065 12.7 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA PF00004.29 OAG33778.1 - 0.12 12.8 0.0 0.41 11.1 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 OAG33778.1 - 0.14 12.0 0.1 0.44 10.5 0.0 1.8 2 0 0 2 2 2 0 NACHT domain PduV-EutP PF10662.9 OAG33778.1 - 0.16 11.7 0.0 0.89 9.3 0.0 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF2218 PF09981.9 OAG33779.1 - 0.11 12.9 1.2 0.19 12.2 1.1 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2218) Allantoicase PF03561.15 OAG33782.1 - 4.5e-89 295.8 0.1 2.4e-45 154.0 0.0 2.1 2 0 0 2 2 2 2 Allantoicase repeat MFS_1 PF07690.16 OAG33783.1 - 1.6e-41 142.4 31.2 1.6e-41 142.4 31.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG33783.1 - 2e-06 26.9 10.3 2e-06 26.9 10.3 2.9 3 1 0 3 3 3 1 Sugar (and other) transporter MAP17 PF15807.5 OAG33783.1 - 0.017 15.4 0.1 0.017 15.4 0.1 1.8 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 RPAP3_C PF13877.6 OAG33784.1 - 0.0036 17.8 0.0 0.0066 17.0 0.0 1.4 1 0 0 1 1 1 1 Potential Monad-binding region of RPAP3 PIF1 PF05970.14 OAG33785.1 - 2.4e-09 36.8 0.2 0.0011 18.2 0.0 2.5 1 1 2 3 3 3 2 PIF1-like helicase ProQ PF04352.13 OAG33785.1 - 0.044 13.7 0.0 0.13 12.1 0.0 1.8 1 0 0 1 1 1 0 ProQ/FINO family Tautomerase_3 PF14832.6 OAG33787.1 - 2.2e-37 128.3 0.0 2.8e-37 128.0 0.0 1.1 1 0 0 1 1 1 1 Putative oxalocrotonate tautomerase enzyme Lactamase_B PF00753.27 OAG33788.1 - 1.8e-17 64.0 0.0 2.9e-17 63.3 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OAG33788.1 - 8.5e-05 22.2 0.1 0.00014 21.5 0.1 1.3 1 1 0 1 1 1 1 Beta-lactamase superfamily domain DUF1631 PF07793.11 OAG33790.1 - 0.13 10.6 0.0 0.21 10.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) Attacin_N PF03768.15 OAG33791.1 - 0.072 13.2 0.0 16 5.7 0.0 2.5 2 0 0 2 2 2 0 Attacin, N-terminal region Spc24 PF08286.11 OAG33792.1 - 0.036 14.3 0.0 0.036 14.3 0.0 1.8 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 NARP1 PF12569.8 OAG33793.1 - 4.6e-198 659.3 22.2 2.7e-196 653.5 11.9 2.4 3 0 0 3 3 3 2 NMDA receptor-regulated protein 1 TPR_19 PF14559.6 OAG33793.1 - 5.3e-23 81.3 24.0 0.00011 22.7 3.5 6.9 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_14 PF13428.6 OAG33793.1 - 8.9e-19 66.6 22.1 0.019 15.7 2.1 11.1 6 4 6 12 12 11 5 Tetratricopeptide repeat TPR_2 PF07719.17 OAG33793.1 - 5.1e-16 57.4 33.0 0.001 19.0 0.1 10.7 11 0 0 11 11 10 5 Tetratricopeptide repeat TPR_16 PF13432.6 OAG33793.1 - 1.4e-14 54.4 31.3 0.01 16.5 5.7 9.1 8 2 4 12 12 12 6 Tetratricopeptide repeat TPR_17 PF13431.6 OAG33793.1 - 6.9e-10 38.6 11.9 0.0017 18.6 0.0 7.6 8 0 0 8 8 8 3 Tetratricopeptide repeat ANAPC3 PF12895.7 OAG33793.1 - 1.3e-09 38.1 20.5 2.3e-06 27.8 2.6 5.1 4 2 0 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 OAG33793.1 - 1.7e-09 37.7 6.8 0.0024 18.0 0.3 5.8 3 1 3 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 OAG33793.1 - 1.2e-08 34.4 24.6 5.8e-05 22.7 0.1 7.7 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_12 PF13424.6 OAG33793.1 - 1.4e-08 34.9 25.3 0.036 14.4 0.2 7.3 7 1 0 7 7 7 5 Tetratricopeptide repeat TPR_8 PF13181.6 OAG33793.1 - 3.4e-08 33.1 27.3 0.0012 18.8 0.0 7.7 8 0 0 8 8 6 4 Tetratricopeptide repeat TPR_15 PF13429.6 OAG33793.1 - 4.7e-06 26.0 15.8 0.0054 16.0 1.0 3.8 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 OAG33793.1 - 6.6e-05 22.5 0.1 6.6e-05 22.5 0.1 4.8 5 1 1 6 6 5 1 TPR repeat DUF2730 PF10805.8 OAG33793.1 - 0.00044 20.3 0.4 15 5.8 0.0 4.5 4 0 0 4 4 4 0 Protein of unknown function (DUF2730) TPR_6 PF13174.6 OAG33793.1 - 0.0065 17.0 29.2 9.1 7.2 0.0 9.9 12 0 0 12 12 10 0 Tetratricopeptide repeat TPR_7 PF13176.6 OAG33793.1 - 0.0099 15.8 19.2 5 7.4 0.1 7.8 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_4 PF07721.14 OAG33793.1 - 0.013 16.1 8.9 0.63 10.8 0.2 5.5 6 0 0 6 6 5 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 OAG33793.1 - 0.016 15.2 12.5 4.4 7.5 0.2 5.6 6 0 0 6 6 5 0 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 OAG33793.1 - 0.049 13.5 17.7 8.2 6.5 0.0 7.3 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_3 PF07720.12 OAG33793.1 - 0.38 10.8 4.7 4.6 7.3 0.1 3.5 4 0 0 4 4 3 0 Tetratricopeptide repeat T6SS_VasJ PF16989.5 OAG33793.1 - 0.77 9.2 7.4 3.9 6.9 0.4 3.5 2 1 1 3 3 3 0 Type VI secretion, EvfE, EvfF, ImpA, BimE, VC_A0119, VasJ BTAD PF03704.17 OAG33793.1 - 9.9 6.6 10.4 13 6.2 0.6 4.2 2 1 2 4 4 4 0 Bacterial transcriptional activator domain Glyco_transf_90 PF05686.12 OAG33794.1 - 1.4e-35 122.9 1.9 2.8e-35 122.0 1.9 1.3 1 1 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.6 OAG33794.1 - 0.0022 18.3 0.1 0.0052 17.2 0.1 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 VDE PF07137.11 OAG33795.1 - 0.13 11.8 0.0 0.16 11.5 0.0 1.1 1 0 0 1 1 1 0 VDE lipocalin domain SIKE PF05769.11 OAG33796.1 - 0.04 13.9 0.2 0.055 13.4 0.2 1.1 1 0 0 1 1 1 0 SIKE family RabGAP-TBC PF00566.18 OAG33796.1 - 0.09 12.4 0.7 0.13 11.9 0.7 1.2 1 0 0 1 1 1 0 Rab-GTPase-TBC domain TPR_10 PF13374.6 OAG33797.1 - 1.7e-59 196.2 11.3 1.6e-09 37.3 0.5 8.5 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_12 PF13424.6 OAG33797.1 - 2.6e-53 178.2 14.7 7.1e-15 55.1 0.5 5.7 3 2 3 6 6 6 6 Tetratricopeptide repeat TPR_7 PF13176.6 OAG33797.1 - 6.1e-13 47.8 7.7 0.0038 17.1 0.2 7.6 7 0 0 7 7 7 2 Tetratricopeptide repeat NB-ARC PF00931.22 OAG33797.1 - 9.5e-12 44.6 0.0 1.8e-10 40.4 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain PNP_UDP_1 PF01048.20 OAG33797.1 - 3e-11 43.0 0.0 9.2e-11 41.4 0.0 1.8 1 1 0 1 1 1 1 Phosphorylase superfamily TPR_1 PF00515.28 OAG33797.1 - 2.7e-08 33.3 1.8 0.013 15.2 0.0 6.6 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_2 PF07719.17 OAG33797.1 - 1.6e-05 24.7 10.6 0.52 10.6 0.1 7.7 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_16 PF13432.6 OAG33797.1 - 3.1e-05 24.5 4.3 0.16 12.6 0.0 5.8 4 1 3 7 7 6 1 Tetratricopeptide repeat AAA_22 PF13401.6 OAG33797.1 - 6e-05 23.3 0.0 0.00018 21.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OAG33797.1 - 6.1e-05 23.5 0.2 0.00057 20.3 0.1 2.8 2 1 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 OAG33797.1 - 0.00013 21.9 0.1 0.00034 20.6 0.1 1.7 1 0 0 1 1 1 1 NACHT domain TPR_MalT PF17874.1 OAG33797.1 - 0.00016 21.2 6.1 0.0032 16.9 1.5 2.5 1 1 1 2 2 2 1 MalT-like TPR region TPR_19 PF14559.6 OAG33797.1 - 0.00022 21.7 1.2 0.075 13.6 0.1 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 OAG33797.1 - 0.002 18.3 2.2 11 6.3 0.0 4.6 3 1 2 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 OAG33797.1 - 0.0036 18.0 9.2 31 5.7 0.1 6.5 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_17 PF13431.6 OAG33797.1 - 0.0043 17.3 2.2 0.76 10.3 0.2 4.6 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 OAG33797.1 - 0.021 15.4 2.9 1.2e+02 3.6 0.1 5.6 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 OAG33797.1 - 0.023 14.9 9.9 2 8.8 0.1 5.6 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_4 PF07721.14 OAG33797.1 - 0.026 15.1 1.5 0.74 10.6 0.1 3.9 4 0 0 4 4 2 0 Tetratricopeptide repeat TniB PF05621.11 OAG33797.1 - 0.043 13.2 0.0 0.097 12.1 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein IstB_IS21 PF01695.17 OAG33797.1 - 0.084 12.6 0.2 1.1 8.9 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein p450 PF00067.22 OAG33798.1 - 5.4e-42 144.1 0.0 3.9e-38 131.4 0.0 2.1 1 1 1 2 2 2 2 Cytochrome P450 Pentapeptide_2 PF01469.18 OAG33800.1 - 7.1e-05 22.6 54.4 0.0018 18.1 22.3 2.2 1 1 1 2 2 2 2 Pentapeptide repeats (8 copies) Sec20 PF03908.13 OAG33800.1 - 0.11 12.4 1.8 0.41 10.6 0.1 2.2 2 0 0 2 2 2 0 Sec20 AAA_5 PF07728.14 OAG33800.1 - 0.12 12.3 2.0 0.6 10.1 2.0 2.0 1 1 1 2 2 2 0 AAA domain (dynein-related subfamily) RCR PF12273.8 OAG33800.1 - 1.9 9.2 5.0 3.6 8.3 5.0 1.6 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red ABC_tran_Xtn PF12848.7 OAG33800.1 - 2.1 8.4 9.9 0.12 12.4 1.4 2.4 2 0 0 2 2 2 0 ABC transporter VWA_3 PF13768.6 OAG33801.1 - 1.8e-28 99.5 0.0 3e-28 98.7 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT PF08487.10 OAG33801.1 - 7.9e-24 84.0 0.0 1.6e-23 83.0 0.0 1.5 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VIT_2 PF13757.6 OAG33801.1 - 2.1e-10 40.4 0.0 4.2e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA PF00092.28 OAG33801.1 - 4.4e-07 30.3 0.0 8.7e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 OAG33801.1 - 1.3e-05 25.8 0.0 3.2e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain NUDE_C PF04880.13 OAG33801.1 - 6 7.3 6.2 13 6.2 6.2 1.5 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region DUF202 PF02656.15 OAG33805.1 - 1.3e-19 70.4 4.5 1.3e-19 70.4 4.5 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF202) SUN PF03856.13 OAG33806.1 - 5.4e-75 252.0 12.7 5.4e-75 252.0 12.7 2.0 2 1 1 3 3 3 1 Beta-glucosidase (SUN family) Bgal_small_N PF02929.17 OAG33807.1 - 9.3e-53 179.3 0.0 1.6e-52 178.5 0.0 1.4 1 1 0 1 1 1 1 Beta galactosidase small chain DUF4981 PF16353.5 OAG33807.1 - 7.8e-18 64.7 0.0 4.8e-17 62.2 0.0 2.2 1 1 0 1 1 1 1 Domain of unknown function(DUF4981) Glyco_hydro_2_C PF02836.17 OAG33808.1 - 9.2e-85 284.4 0.0 1.4e-84 283.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.18 OAG33808.1 - 8.4e-46 156.0 0.0 2.3e-45 154.5 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.21 OAG33808.1 - 7.8e-16 58.7 0.0 1.3e-15 58.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.6 OAG33808.1 - 0.017 15.7 0.0 0.045 14.3 0.0 1.7 1 0 0 1 1 1 0 Beta-galactosidase jelly roll domain Peptidase_S39 PF02122.15 OAG33809.1 - 0.033 13.7 0.1 0.042 13.4 0.1 1.1 1 0 0 1 1 1 0 Peptidase S39 LURAP PF14854.6 OAG33809.1 - 0.039 13.9 0.6 3.3 7.7 0.1 2.2 2 0 0 2 2 2 0 Leucine rich adaptor protein MRF_C1 PF13887.6 OAG33809.1 - 0.11 11.7 0.8 0.2 10.9 0.8 1.4 1 0 0 1 1 1 0 Myelin gene regulatory factor -C-terminal domain 1 SlyX PF04102.12 OAG33809.1 - 0.51 11.0 3.8 1.5 9.5 0.4 2.3 2 0 0 2 2 2 0 SlyX RNA_capsid PF03035.14 OAG33810.1 - 0.02 14.9 1.5 0.027 14.5 1.5 1.1 1 0 0 1 1 1 0 Calicivirus putative RNA polymerase/capsid protein AUDH_Cupin PF18637.1 OAG33811.1 - 0.17 11.9 0.1 0.3 11.1 0.1 1.4 1 0 0 1 1 1 0 Aldos-2-ulose dehydratase/isomerase (AUDH) Cupin domain Thiolase_N PF00108.23 OAG33813.1 - 2.3e-75 253.3 1.8 2.3e-75 253.3 1.8 1.4 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 OAG33813.1 - 1.6e-41 140.8 0.0 2.7e-41 140.1 0.0 1.4 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 OAG33813.1 - 0.049 13.2 2.4 0.96 9.0 1.1 3.1 2 1 1 3 3 3 0 Beta-ketoacyl synthase, N-terminal domain Sigma_1s PF02454.16 OAG33814.1 - 0.21 11.6 1.4 0.43 10.6 1.4 1.5 1 0 0 1 1 1 0 Sigma 1s protein Aldo_ket_red PF00248.21 OAG33815.1 - 3.9e-69 233.1 0.1 4.5e-69 232.9 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family RHH_1 PF01402.21 OAG33815.1 - 1.1 9.3 3.5 1.8 8.6 0.0 2.9 3 0 0 3 3 3 0 Ribbon-helix-helix protein, copG family Ank_4 PF13637.6 OAG33816.1 - 1.7e-13 50.8 0.5 0.00018 22.0 0.0 3.7 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OAG33816.1 - 5.1e-12 46.2 0.0 4.6e-08 33.5 0.0 2.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 OAG33816.1 - 2.3e-11 43.6 2.0 0.0018 18.6 0.3 4.3 4 1 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 OAG33816.1 - 2.3e-11 42.9 0.6 0.0082 16.6 0.1 4.9 4 1 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 OAG33816.1 - 5.9e-09 36.0 0.4 0.0016 18.7 0.0 3.4 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Nodulin_late PF07127.11 OAG33817.1 - 0.032 14.6 13.4 0.44 10.9 0.5 3.2 3 0 0 3 3 3 0 Late nodulin protein Gamma-thionin PF00304.20 OAG33817.1 - 2.6 8.4 36.1 3.3 8.1 6.0 3.4 3 0 0 3 3 3 0 Gamma-thionin family Squash PF00299.18 OAG33817.1 - 7.5 6.7 29.5 4.5 7.4 4.3 3.4 3 0 0 3 3 3 0 Squash family serine protease inhibitor AA_permease_2 PF13520.6 OAG33818.1 - 1.6e-49 168.9 51.8 2.3e-49 168.4 51.8 1.2 1 0 0 1 1 1 1 Amino acid permease Fungal_trans_2 PF11951.8 OAG33818.1 - 5.8e-31 107.7 1.0 9.7e-31 106.9 1.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain AA_permease PF00324.21 OAG33818.1 - 1.1e-16 60.5 41.7 1.6e-16 60.0 41.7 1.1 1 0 0 1 1 1 1 Amino acid permease PhyH PF05721.13 OAG33819.1 - 3.5e-20 73.2 0.0 4.8e-20 72.7 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Sugar_tr PF00083.24 OAG33820.1 - 5.7e-62 210.1 11.6 6.9e-62 209.8 11.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG33820.1 - 9e-27 93.9 17.6 9e-27 93.9 17.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 OAG33820.1 - 0.00014 20.3 0.9 0.047 12.0 0.0 2.5 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family HrpF PF06266.12 OAG33820.1 - 0.22 11.9 0.3 0.4 11.0 0.3 1.4 1 0 0 1 1 1 0 HrpF protein Pkinase PF00069.25 OAG33821.1 - 2.1e-28 99.4 0.0 1.4e-27 96.7 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG33821.1 - 7.2e-08 32.0 0.7 1.6e-06 27.6 0.7 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAG33821.1 - 0.015 14.1 0.0 0.019 13.8 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 OAG33821.1 - 0.048 13.3 0.0 0.076 12.6 0.0 1.3 1 0 0 1 1 1 0 RIO1 family FMO-like PF00743.19 OAG33822.1 - 9.5e-20 70.5 0.0 1.7e-17 63.1 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 OAG33822.1 - 6.4e-17 61.7 0.0 1.7e-13 50.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG33822.1 - 2.6e-16 59.8 0.0 7e-15 55.1 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG33822.1 - 1.2e-14 54.2 0.2 1.3e-11 44.3 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 OAG33822.1 - 3.2e-11 43.3 0.0 3.4e-09 36.8 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 OAG33822.1 - 6.3e-10 39.3 0.2 0.11 12.5 0.0 4.4 4 0 0 4 4 4 3 FAD-NAD(P)-binding Pyr_redox PF00070.27 OAG33822.1 - 5.6e-07 30.0 0.4 0.0053 17.3 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAG33822.1 - 4.2e-06 26.6 0.0 0.028 14.0 0.2 3.8 3 1 1 4 4 4 1 FAD dependent oxidoreductase Thi4 PF01946.17 OAG33822.1 - 3.5e-05 23.2 0.6 0.00081 18.7 0.1 2.5 3 0 0 3 3 3 1 Thi4 family Shikimate_DH PF01488.20 OAG33822.1 - 0.0014 18.7 0.2 0.014 15.5 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase GIDA PF01134.22 OAG33822.1 - 0.0017 17.5 0.0 0.28 10.2 0.0 2.9 3 0 0 3 3 3 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 OAG33822.1 - 0.0043 16.2 0.0 0.67 8.9 0.0 2.3 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_7 PF13241.6 OAG33822.1 - 0.011 16.1 0.1 0.4 11.1 0.0 2.7 2 0 0 2 2 2 0 Putative NAD(P)-binding FAD_binding_2 PF00890.24 OAG33822.1 - 0.054 12.6 0.0 0.11 11.5 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain Melibiase_C PF17801.1 OAG33822.1 - 0.083 13.0 0.0 7.4 6.7 0.0 2.6 2 0 0 2 2 2 0 Alpha galactosidase C-terminal beta sandwich domain HI0933_like PF03486.14 OAG33822.1 - 0.73 8.5 2.1 10 4.7 0.1 3.1 4 0 0 4 4 4 0 HI0933-like protein Metallophos PF00149.28 OAG33823.1 - 1.7e-07 31.9 0.9 3.6e-07 30.9 0.9 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase COesterase PF00135.28 OAG33824.1 - 2.4e-60 204.9 0.0 3.2e-60 204.5 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAG33824.1 - 2.7e-05 24.1 0.0 0.017 15.0 0.0 2.6 2 0 0 2 2 2 2 alpha/beta hydrolase fold Pkinase PF00069.25 OAG33825.1 - 2.5e-26 92.6 0.0 3.2e-26 92.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG33825.1 - 7e-14 51.7 0.0 9.6e-14 51.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAG33825.1 - 4.2e-09 35.7 0.0 6.5e-09 35.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OAG33825.1 - 0.00019 21.4 0.0 0.0014 18.6 0.0 2.0 1 1 0 2 2 2 1 Phosphotransferase enzyme family AhpC-TSA PF00578.21 OAG33826.1 - 2.5e-23 82.3 0.0 4.9e-23 81.4 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 OAG33826.1 - 6.9e-16 58.3 0.0 1.2e-15 57.5 0.0 1.4 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 OAG33826.1 - 0.0051 16.9 0.0 0.01 16.0 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme Sedlin_N PF04628.13 OAG33827.1 - 2.5e-16 60.0 0.0 4e-16 59.3 0.0 1.4 1 1 0 1 1 1 1 Sedlin, N-terminal conserved region Oxidored_q6 PF01058.22 OAG33828.1 - 3.4e-22 78.7 0.0 6e-22 77.9 0.0 1.4 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Trypan_PARP PF05887.11 OAG33830.1 - 0.0026 17.7 12.3 0.0044 17.0 12.3 1.2 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) RBFA PF02033.18 OAG33831.1 - 0.063 13.7 0.1 0.1 13.1 0.1 1.3 1 0 0 1 1 1 0 Ribosome-binding factor A p450 PF00067.22 OAG33832.1 - 1.8e-56 191.8 0.0 2.3e-56 191.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF5026 PF16429.5 OAG33834.1 - 0.035 14.2 0.0 0.055 13.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5026) PAP_central PF04928.17 OAG33835.1 - 0.00053 19.0 0.0 0.00068 18.7 0.0 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain Iso_dh PF00180.20 OAG33836.1 - 1.1e-87 294.5 0.0 1.3e-87 294.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Tape_meas_lam_C PF09718.10 OAG33836.1 - 0.13 12.4 0.4 0.22 11.7 0.4 1.4 1 0 0 1 1 1 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) DEAD PF00270.29 OAG33837.1 - 6.4e-37 127.0 0.2 9.1e-36 123.2 0.0 2.5 2 1 0 2 2 2 1 DEAD/DEAH box helicase DUF4217 PF13959.6 OAG33837.1 - 6.6e-20 71.1 0.0 1.2e-19 70.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.31 OAG33837.1 - 1.9e-18 66.8 0.0 5.4e-18 65.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG33837.1 - 4.7e-05 23.5 0.0 0.00014 22.0 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 OAG33837.1 - 0.058 13.7 0.7 0.74 10.1 0.0 2.8 3 0 0 3 3 3 0 AAA domain Sugar_tr PF00083.24 OAG33838.1 - 5.1e-82 276.1 21.9 6.1e-82 275.9 21.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG33838.1 - 2.4e-20 72.8 58.5 4.1e-17 62.1 29.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4017 PF13209.6 OAG33838.1 - 0.07 13.1 1.6 0.26 11.2 1.6 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4017) DUF2964 PF11177.8 OAG33838.1 - 0.47 10.7 6.5 6.2 7.1 3.5 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2964) adh_short_C2 PF13561.6 OAG33839.1 - 8.2e-59 199.0 0.2 1e-58 198.7 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG33839.1 - 6.7e-46 156.2 0.1 8.5e-46 155.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG33839.1 - 6.5e-08 32.7 0.2 1.6e-07 31.4 0.2 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG33839.1 - 0.0024 17.4 0.4 0.008 15.7 0.4 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 OAG33839.1 - 0.0034 17.6 0.2 0.0058 16.9 0.2 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain 3HCDH_N PF02737.18 OAG33839.1 - 0.045 13.6 1.0 0.068 13.1 1.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 OAG33839.1 - 0.097 12.0 0.0 0.18 11.1 0.0 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 2-Hacid_dh_C PF02826.19 OAG33839.1 - 0.12 11.7 0.2 0.2 11.0 0.2 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HI0933_like PF03486.14 OAG33839.1 - 0.24 10.1 1.6 0.3 9.7 1.6 1.1 1 0 0 1 1 1 0 HI0933-like protein Abhydrolase_3 PF07859.13 OAG33840.1 - 1.1e-58 198.6 0.0 1.5e-58 198.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OAG33840.1 - 5.1e-06 26.1 0.0 0.0056 16.2 0.0 2.3 1 1 0 2 2 2 2 Prolyl oligopeptidase family COesterase PF00135.28 OAG33840.1 - 0.0014 17.6 0.0 0.0062 15.5 0.0 1.8 1 1 0 1 1 1 1 Carboxylesterase family DLH PF01738.18 OAG33840.1 - 0.12 11.9 0.2 0.33 10.5 0.0 1.6 2 0 0 2 2 2 0 Dienelactone hydrolase family Esterase_phd PF10503.9 OAG33840.1 - 0.14 11.7 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Esterase PHB depolymerase Lactamase_B PF00753.27 OAG33841.1 - 5.2e-10 39.7 2.4 7.6e-10 39.1 2.4 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OAG33841.1 - 0.0038 16.7 0.0 0.0057 16.2 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain FMO-like PF00743.19 OAG33842.1 - 5.1e-20 71.4 0.0 2e-18 66.1 0.0 2.2 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 OAG33842.1 - 6.3e-10 38.8 0.0 1.2e-08 34.5 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG33842.1 - 3.1e-09 36.9 0.0 7.4e-09 35.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 OAG33842.1 - 4e-08 32.9 0.0 2.7e-06 26.9 0.0 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG33842.1 - 8.8e-06 25.1 0.0 0.0018 17.5 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 OAG33842.1 - 9.1e-06 25.5 0.0 0.44 10.1 0.1 3.2 1 1 2 3 3 3 3 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 OAG33842.1 - 0.00029 20.8 0.9 0.01 15.8 0.0 3.3 4 1 0 4 4 4 1 FAD-NAD(P)-binding Amino_oxidase PF01593.24 OAG33842.1 - 0.0081 15.5 0.0 6.5 5.9 0.1 3.4 2 2 1 3 3 3 1 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 OAG33842.1 - 0.03 13.4 0.0 0.18 10.8 0.0 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox PF00070.27 OAG33842.1 - 0.078 13.6 0.3 6.3 7.4 0.0 2.7 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAG33842.1 - 0.13 11.5 0.2 1.3 8.2 0.0 2.4 3 0 0 3 3 3 0 Thi4 family Fungal_trans_2 PF11951.8 OAG33843.1 - 2.1e-06 26.8 8.1 9e-06 24.7 4.4 2.3 1 1 0 2 2 2 2 Fungal specific transcription factor domain RELT PF12606.8 OAG33843.1 - 0.023 13.7 0.1 0.044 12.8 0.1 1.4 1 0 0 1 1 1 0 Tumour necrosis factor receptor superfamily member 19 Ras PF00071.22 OAG33845.1 - 8.1e-50 168.6 0.0 1e-49 168.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAG33845.1 - 5e-21 75.1 0.0 8.2e-21 74.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAG33845.1 - 4.2e-06 26.3 0.0 9.2e-06 25.2 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family AAA_7 PF12775.7 OAG33845.1 - 0.022 14.3 0.0 0.039 13.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region PAP2 PF01569.21 OAG33846.1 - 1.4e-19 70.2 1.3 4.6e-19 68.5 1.3 1.9 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 OAG33846.1 - 0.00075 19.2 4.3 0.0025 17.5 4.3 2.0 1 1 0 1 1 1 1 PAP2 superfamily Peptidase_C48 PF02902.19 OAG33847.1 - 8.9e-24 84.5 0.0 1.5e-23 83.8 0.0 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain YihI PF04220.12 OAG33847.1 - 0.0085 15.8 0.2 0.0085 15.8 0.2 2.0 2 1 1 3 3 3 1 Der GTPase activator (YihI) DUF4404 PF14357.6 OAG33847.1 - 0.79 10.4 3.5 2 9.1 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) Na_trans_assoc PF06512.13 OAG33847.1 - 1.4 9.1 7.6 3.6 7.8 7.6 1.6 1 0 0 1 1 1 0 Sodium ion transport-associated Rad4 PF03835.15 OAG33848.1 - 7.1e-38 129.6 0.9 1.5e-37 128.6 0.9 1.5 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.9 OAG33848.1 - 9.3e-27 93.3 0.1 1.7e-26 92.4 0.1 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 OAG33848.1 - 2e-18 66.0 0.2 3.8e-18 65.1 0.2 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 OAG33848.1 - 4.2e-18 66.0 1.4 4.2e-18 66.0 1.4 2.5 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.19 OAG33848.1 - 0.011 16.2 0.0 0.065 13.7 0.0 2.3 2 1 0 2 2 2 0 Transglutaminase-like superfamily DUF5132 PF17195.4 OAG33848.1 - 0.7 10.0 2.4 1.8 8.7 0.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF5132) AATF-Che1 PF13339.6 OAG33849.1 - 1.2e-30 107.0 1.1 1.2e-30 107.0 1.1 2.1 3 0 0 3 3 3 1 Apoptosis antagonizing transcription factor TRAUB PF08164.12 OAG33849.1 - 9.4e-27 93.4 0.0 2.4e-26 92.1 0.0 1.8 1 0 0 1 1 1 1 Apoptosis-antagonizing transcription factor, C-terminal QWRF PF04484.12 OAG33849.1 - 0.78 9.4 7.6 0.03 14.1 1.2 1.9 2 1 0 2 2 2 0 QWRF family MF_alpha_N PF05436.11 OAG33851.1 - 0.095 12.6 0.1 0.15 12.0 0.1 1.3 1 0 0 1 1 1 0 Mating factor alpha precursor N-terminus cwf21 PF08312.12 OAG33852.1 - 0.087 13.0 0.0 2.7 8.2 0.0 2.4 2 0 0 2 2 2 0 cwf21 domain CwfJ_C_1 PF04677.15 OAG33853.1 - 3.5e-19 68.9 0.0 5.6e-19 68.2 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 OAG33853.1 - 7.5e-09 36.4 0.0 1.5e-08 35.4 0.0 1.5 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 GLTP PF08718.11 OAG33854.1 - 4.1e-41 140.7 0.0 5.2e-41 140.4 0.0 1.1 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) PH_4 PF15404.6 OAG33855.1 - 1.6e-59 200.8 0.1 3e-58 196.6 0.0 2.6 3 0 0 3 3 3 1 Pleckstrin homology domain Spo7_2_N PF15407.6 OAG33855.1 - 4.6e-26 90.2 1.0 4.6e-26 90.2 1.0 2.1 2 0 0 2 2 2 1 Sporulation protein family 7 PH PF00169.29 OAG33855.1 - 5e-10 39.8 0.4 0.067 13.7 0.0 5.2 4 1 0 4 4 4 3 PH domain PH_6 PF15406.6 OAG33855.1 - 0.014 15.7 0.0 3.9 7.8 0.0 2.7 2 0 0 2 2 2 0 Pleckstrin homology domain Cupin_8 PF13621.6 OAG33856.1 - 2.4e-16 60.2 0.2 8.6e-14 51.9 0.0 2.8 2 1 0 2 2 2 1 Cupin-like domain JmjC PF02373.22 OAG33856.1 - 3.1e-10 40.5 0.1 1.7e-09 38.1 0.1 2.1 1 1 0 1 1 1 1 JmjC domain, hydroxylase F-box-like PF12937.7 OAG33856.1 - 9.1e-07 28.7 0.0 2e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAG33856.1 - 0.00058 19.7 0.1 0.0031 17.3 0.0 2.2 3 0 0 3 3 3 1 F-box domain NuA4 PF09340.10 OAG33857.1 - 1.3e-20 73.0 1.1 2.2e-20 72.3 0.0 2.0 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 NUDIX PF00293.28 OAG33858.1 - 3.9e-11 43.1 0.2 1.1e-10 41.7 0.0 1.8 1 1 1 2 2 2 1 NUDIX domain PHINT_rpt PF14882.6 OAG33858.1 - 0.038 14.3 2.5 0.11 12.8 2.5 1.8 1 0 0 1 1 1 0 Phage-integrase repeat unit Glyco_hydro_38N PF01074.22 OAG33860.1 - 3.7e-88 295.6 1.2 8.5e-88 294.4 1.2 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 OAG33860.1 - 5.8e-58 196.5 0.0 3.6e-57 193.9 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 OAG33860.1 - 5.3e-27 93.8 0.1 1.1e-26 92.8 0.1 1.6 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 OAG33860.1 - 7.8e-10 38.7 0.0 1.8e-09 37.6 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain CAP_GLY PF01302.25 OAG33861.1 - 4.3e-16 58.7 0.2 8.4e-16 57.7 0.2 1.5 1 0 0 1 1 1 1 CAP-Gly domain CLIP1_ZNF PF16641.5 OAG33861.1 - 1e-07 31.7 11.5 0.0013 18.6 1.1 2.5 2 0 0 2 2 2 2 CLIP1 zinc knuckle DUF812 PF05667.11 OAG33861.1 - 0.00022 20.3 18.8 0.00022 20.3 18.8 2.5 1 1 1 2 2 1 1 Protein of unknown function (DUF812) EzrA PF06160.12 OAG33861.1 - 0.00095 17.5 21.1 0.0031 15.7 20.7 2.1 1 1 0 1 1 1 1 Septation ring formation regulator, EzrA Paramyx_P_V_C PF03210.13 OAG33861.1 - 0.0054 16.5 0.3 0.017 14.9 0.0 2.0 2 0 0 2 2 2 1 Paramyxovirus P/V phosphoprotein C-terminal DUF3584 PF12128.8 OAG33861.1 - 0.016 12.8 24.9 0.024 12.2 24.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Fez1 PF06818.15 OAG33861.1 - 0.016 15.7 34.4 0.45 10.9 19.3 3.2 2 1 0 3 3 3 0 Fez1 PKcGMP_CC PF16808.5 OAG33861.1 - 0.016 15.0 0.1 0.016 15.0 0.1 5.0 5 1 1 6 6 6 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Spc7 PF08317.11 OAG33861.1 - 0.044 12.7 35.8 0.077 11.9 12.6 3.2 2 1 1 3 3 3 0 Spc7 kinetochore protein HR1 PF02185.16 OAG33861.1 - 0.16 12.1 0.0 0.16 12.1 0.0 4.6 3 1 0 3 3 2 0 Hr1 repeat AAA_13 PF13166.6 OAG33861.1 - 0.19 10.3 25.0 0.013 14.2 10.0 2.9 2 1 1 3 3 3 0 AAA domain TcdB_N PF12918.7 OAG33861.1 - 0.28 11.5 7.2 13 6.1 0.2 3.7 4 0 0 4 4 4 0 TcdB toxin N-terminal helical domain DUF241 PF03087.14 OAG33861.1 - 0.29 10.9 12.0 0.32 10.8 5.6 2.8 1 1 1 2 2 2 0 Arabidopsis protein of unknown function DUF5339 PF17274.2 OAG33861.1 - 0.31 11.9 6.3 6.5 7.7 0.3 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5339) DUF1664 PF07889.12 OAG33861.1 - 0.34 10.9 18.9 0.2 11.7 4.1 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF1664) V-SNARE PF05008.15 OAG33861.1 - 0.8 10.1 12.6 9.4 6.7 0.1 3.6 2 1 1 3 3 3 0 Vesicle transport v-SNARE protein N-terminus Ribonuc_2-5A PF06479.12 OAG33861.1 - 1.1 9.5 3.7 1.3 9.2 0.7 2.3 2 0 0 2 2 2 0 Ribonuclease 2-5A DASH_Dad4 PF08650.10 OAG33861.1 - 1.5 8.9 3.8 5.9 6.9 0.8 2.6 2 0 0 2 2 2 0 DASH complex subunit Dad4 RSS_P20 PF11757.8 OAG33861.1 - 1.7 9.1 8.4 0.29 11.6 2.7 2.5 1 1 2 3 3 3 0 Suppressor of RNA silencing P21-like N-terminal domain Fib_alpha PF08702.10 OAG33861.1 - 1.8 8.7 19.5 1.2 9.3 2.8 3.9 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family NPV_P10 PF05531.12 OAG33861.1 - 2 9.0 21.0 0.23 12.0 3.2 4.5 4 1 1 5 5 5 0 Nucleopolyhedrovirus P10 protein Laminin_II PF06009.12 OAG33861.1 - 2.8 8.0 20.6 0.5 10.4 1.7 3.4 2 2 2 4 4 4 0 Laminin Domain II DUF4407 PF14362.6 OAG33861.1 - 3.3 7.0 27.1 6.6 6.0 7.0 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) Sec8_exocyst PF04048.14 OAG33861.1 - 4.3 7.2 11.3 1.2 9.1 0.7 3.7 4 0 0 4 4 4 0 Sec8 exocyst complex component specific domain BLOC1_2 PF10046.9 OAG33861.1 - 5.8 7.3 23.5 0.47 10.8 4.7 4.1 4 0 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Golgin_A5 PF09787.9 OAG33861.1 - 6.5 6.1 37.7 2.7 7.4 16.2 3.1 2 1 1 3 3 3 0 Golgin subfamily A member 5 Macoilin PF09726.9 OAG33861.1 - 8.9 4.7 24.4 8.8 4.7 22.8 1.7 1 1 0 1 1 1 0 Macoilin family FMO-like PF00743.19 OAG33862.1 - 3.5e-16 58.7 0.3 5.8e-14 51.4 0.2 2.7 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OAG33862.1 - 2.7e-11 43.5 0.0 5.9e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAG33862.1 - 1.6e-10 40.7 0.0 2e-08 33.9 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG33862.1 - 3e-08 33.3 0.2 5.4e-07 29.2 0.1 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG33862.1 - 4e-08 32.8 0.5 0.039 13.1 0.1 3.8 4 0 0 4 4 4 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 OAG33862.1 - 0.00018 21.2 1.2 0.72 9.4 0.1 3.2 2 1 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 OAG33862.1 - 0.0006 19.8 0.3 0.0097 15.9 0.0 2.7 3 1 0 3 3 3 1 FAD-NAD(P)-binding Shikimate_DH PF01488.20 OAG33862.1 - 0.0041 17.2 0.0 12 6.0 0.0 4.0 4 0 0 4 4 4 1 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.24 OAG33862.1 - 0.0047 16.1 0.1 2.5 7.1 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain AlaDh_PNT_C PF01262.21 OAG33862.1 - 0.019 14.3 0.0 0.045 13.0 0.0 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 OAG33862.1 - 0.021 14.1 0.2 0.16 11.2 0.0 2.4 3 0 0 3 3 3 0 Thi4 family GIDA PF01134.22 OAG33862.1 - 0.19 10.8 0.2 2.1 7.3 0.2 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A TauD PF02668.16 OAG33863.1 - 1.5e-53 182.3 0.2 1.8e-53 182.1 0.2 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF4490 PF14892.6 OAG33863.1 - 0.13 12.4 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4490) HpcH_HpaI PF03328.14 OAG33864.1 - 1.6e-31 109.1 0.0 2.1e-31 108.8 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family p450 PF00067.22 OAG33865.1 - 1.7e-71 241.4 0.0 2.2e-71 241.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_cc PF11790.8 OAG33866.1 - 0.016 14.8 2.6 0.047 13.3 2.6 1.8 1 1 0 1 1 1 0 Glycosyl hydrolase catalytic core Sugar_tr PF00083.24 OAG33867.1 - 7.4e-94 315.2 24.5 8.4e-94 315.0 24.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG33867.1 - 4.5e-29 101.5 26.1 4.5e-29 101.5 26.1 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF5345 PF17280.2 OAG33867.1 - 0.2 11.7 2.2 4.1 7.4 0.9 3.2 2 1 1 3 3 3 0 Family of unknown function (DUF5345) DIOX_N PF14226.6 OAG33868.1 - 3.6e-20 72.9 0.0 6.8e-20 72.0 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OAG33868.1 - 2.2e-13 50.5 0.1 3.5e-13 49.9 0.1 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PhyH PF05721.13 OAG33869.1 - 1.6e-22 80.8 0.0 2.2e-22 80.3 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) PhyH PF05721.13 OAG33870.1 - 2.1e-21 77.1 0.0 3.4e-21 76.5 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_3 PF13640.6 OAG33870.1 - 0.093 13.6 0.0 0.16 12.9 0.0 1.4 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Zn_clus PF00172.18 OAG33871.1 - 1.3e-07 31.6 13.5 2.1e-07 30.9 13.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain His_Phos_2 PF00328.22 OAG33872.1 - 0.00025 20.5 0.0 0.023 14.0 0.0 2.4 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) FAD_binding_2 PF00890.24 OAG33873.1 - 7.8e-117 390.9 3.2 1.2e-116 390.2 3.2 1.3 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 OAG33873.1 - 1e-42 145.2 0.4 1.7e-42 144.5 0.4 1.4 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 OAG33873.1 - 6.8e-06 25.5 0.1 0.0017 17.7 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAG33873.1 - 0.00015 21.5 0.1 0.00029 20.6 0.1 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 OAG33873.1 - 0.0065 15.8 1.0 0.013 14.8 1.0 1.5 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 OAG33873.1 - 0.0076 15.0 0.3 0.35 9.5 0.1 2.9 3 0 0 3 3 3 1 HI0933-like protein Thi4 PF01946.17 OAG33873.1 - 0.01 15.1 0.4 0.17 11.1 0.1 2.4 2 0 0 2 2 2 0 Thi4 family GIDA PF01134.22 OAG33873.1 - 0.018 14.2 2.7 0.21 10.7 2.8 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 OAG33873.1 - 0.18 11.0 0.9 0.95 8.7 0.1 2.4 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Ribonucleas_3_3 PF14622.6 OAG33874.1 - 1e-21 77.4 0.0 2.9e-21 76.0 0.0 1.7 1 1 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 OAG33874.1 - 0.00012 22.7 0.0 0.00065 20.3 0.0 2.3 2 1 0 2 2 2 1 Ribonuclease III domain Adap_comp_sub PF00928.21 OAG33875.1 - 3.2e-85 285.7 0.0 7e-85 284.6 0.0 1.5 2 0 0 2 2 2 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 OAG33875.1 - 3.4e-09 36.8 0.3 5.7e-09 36.0 0.3 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Ank_4 PF13637.6 OAG33876.1 - 1.3e-14 54.4 0.3 1.3e-07 32.0 0.1 2.6 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 OAG33876.1 - 3.6e-13 49.3 0.8 2.9e-09 37.0 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 OAG33876.1 - 1.8e-12 47.7 0.1 2.1e-11 44.3 0.0 2.5 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OAG33876.1 - 5.1e-11 42.6 0.4 8e-10 38.8 0.1 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG33876.1 - 1.8e-09 37.0 0.1 3.1e-07 30.2 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat DUF5465 PF17553.2 OAG33876.1 - 0.09 13.3 0.2 0.26 11.9 0.2 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5465) CTP_transf_1 PF01148.20 OAG33877.1 - 0.0057 16.5 2.2 0.0094 15.7 2.2 1.3 1 1 0 1 1 1 1 Cytidylyltransferase family Aldolase_II PF00596.21 OAG33878.1 - 2.1e-39 135.4 0.4 3e-39 134.9 0.4 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Zn_clus PF00172.18 OAG33879.1 - 0.00016 21.7 12.9 0.00028 20.9 12.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAG33879.1 - 0.0014 17.7 0.0 0.0046 16.0 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Epimerase PF01370.21 OAG33880.1 - 8.1e-12 45.1 0.0 1.3e-11 44.4 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 OAG33880.1 - 3.9e-07 29.5 0.0 4.7e-06 26.0 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 OAG33880.1 - 4.3e-05 23.1 0.0 6.6e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 OAG33880.1 - 0.0011 18.8 0.0 0.0017 18.3 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 OAG33880.1 - 0.017 14.3 0.0 0.036 13.2 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain 3Beta_HSD PF01073.19 OAG33880.1 - 0.022 13.8 0.0 0.033 13.2 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 OAG33880.1 - 0.22 10.6 0.0 0.34 10.0 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Fungal_trans PF04082.18 OAG33881.1 - 2.2e-13 49.8 0.4 4e-13 49.0 0.4 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain RPE65 PF03055.15 OAG33882.1 - 4e-106 356.0 0.1 4.5e-106 355.8 0.1 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein tRNA-synt_2b PF00587.25 OAG33883.1 - 7.5e-21 74.9 0.0 1.9e-19 70.4 0.0 2.3 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 OAG33883.1 - 5.6e-09 36.2 2.6 9.2e-09 35.5 2.6 1.3 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain GAS PF13851.6 OAG33883.1 - 0.047 13.0 0.9 0.076 12.4 0.9 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF724 PF05266.14 OAG33883.1 - 0.13 12.1 1.1 0.21 11.4 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Amidohydro_2 PF04909.14 OAG33884.1 - 5.3e-42 144.6 0.1 6.6e-42 144.3 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase adh_short PF00106.25 OAG33885.1 - 6.1e-32 110.7 0.0 8.9e-32 110.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG33885.1 - 1.1e-21 77.5 0.0 1.7e-21 76.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 OAG33885.1 - 0.0079 15.7 0.0 0.02 14.4 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OAG33885.1 - 0.18 10.8 0.0 0.27 10.2 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family FTA2 PF13095.6 OAG33886.1 - 1.1e-38 133.0 0.0 4.5e-38 131.0 0.0 1.7 1 1 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Ank_4 PF13637.6 OAG33887.1 - 9.6e-09 35.6 0.0 5.9e-05 23.5 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OAG33887.1 - 1.2e-06 29.0 0.0 2.6e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OAG33887.1 - 0.00041 20.6 0.2 0.011 16.0 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG33887.1 - 0.0085 16.5 0.0 0.077 13.6 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat DUF3290 PF11694.8 OAG33888.1 - 0.71 9.8 0.0 0.71 9.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3290) FMO-like PF00743.19 OAG33889.1 - 3.9e-17 61.9 0.9 2.3e-16 59.3 0.1 2.3 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OAG33889.1 - 9.9e-11 41.7 0.0 2.2e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 OAG33889.1 - 5.1e-07 29.2 0.0 0.00016 20.9 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 OAG33889.1 - 2.2e-06 27.2 0.0 1.7e-05 24.2 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAG33889.1 - 5.4e-06 26.5 0.0 2.9e-05 24.1 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 OAG33889.1 - 3.8e-05 23.1 0.0 0.00019 20.8 0.0 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAG33889.1 - 0.075 12.6 0.0 3.5 7.1 0.0 2.6 2 1 1 3 3 3 0 FAD dependent oxidoreductase Thi4 PF01946.17 OAG33889.1 - 0.23 10.7 0.0 1.4 8.1 0.0 2.1 2 0 0 2 2 2 0 Thi4 family AA_permease PF00324.21 OAG33890.1 - 1.8e-94 317.0 39.6 2.3e-94 316.7 39.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAG33890.1 - 4.4e-26 91.7 43.2 5.3e-26 91.4 43.2 1.1 1 0 0 1 1 1 1 Amino acid permease EthD PF07110.11 OAG33891.1 - 5.3e-09 37.1 0.1 1.3e-08 35.9 0.1 1.6 1 1 0 1 1 1 1 EthD domain HSP70 PF00012.20 OAG33892.1 - 1.5e-261 868.8 3.8 1.7e-261 868.7 3.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 OAG33892.1 - 1.1e-16 60.6 0.0 1.7e-15 56.7 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 OAG33892.1 - 0.0027 18.1 1.0 7.1 7.1 0.0 3.5 3 1 0 3 3 3 2 Cell division protein FtsA FGGY_C PF02782.16 OAG33892.1 - 0.0028 17.4 0.0 0.0064 16.2 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.18 OAG33892.1 - 0.02 14.1 0.1 0.043 13.1 0.1 1.6 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase GRP PF07172.11 OAG33892.1 - 0.23 12.2 9.0 0.56 10.9 9.0 1.6 1 0 0 1 1 1 0 Glycine rich protein family Golgin_A5 PF09787.9 OAG33892.1 - 1.5 8.2 6.9 0.89 9.0 3.3 1.9 2 0 0 2 2 2 0 Golgin subfamily A member 5 CHZ PF09649.10 OAG33893.1 - 1e-11 44.1 3.2 1e-11 44.1 3.2 2.9 3 0 0 3 3 3 1 Histone chaperone domain CHZ MFAP1 PF06991.11 OAG33893.1 - 0.35 10.7 17.6 0.43 10.4 17.6 1.3 1 0 0 1 1 1 0 Microfibril-associated/Pre-mRNA processing Ssl1 PF04056.14 OAG33894.1 - 2.6e-65 219.9 0.0 4.3e-65 219.1 0.0 1.3 1 0 0 1 1 1 1 Ssl1-like VWA_2 PF13519.6 OAG33894.1 - 1e-15 58.3 0.0 2.6e-15 57.0 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VEFS-Box PF09733.9 OAG33894.1 - 1.9e-05 24.5 1.4 0.00021 21.1 2.7 2.0 2 0 0 2 2 2 1 VEFS-Box of polycomb protein zf-C4H2 PF10146.9 OAG33894.1 - 0.0022 18.3 1.1 0.0073 16.6 1.1 1.8 1 0 0 1 1 1 1 Zinc finger-containing protein NPR3 PF03666.13 OAG33894.1 - 1.2 7.8 4.4 0.49 9.1 0.7 2.0 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 Peptidase_M1 PF01433.20 OAG33895.1 - 5.8e-84 281.0 3.6 1.1e-83 280.1 3.6 1.5 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 OAG33895.1 - 2.6e-82 276.9 0.1 4.9e-82 276.0 0.1 1.5 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Ras PF00071.22 OAG33895.1 - 4.6e-64 214.9 1.6 6.3e-64 214.5 0.5 1.8 2 0 0 2 2 2 1 Ras family Peptidase_M1_N PF17900.1 OAG33895.1 - 3e-42 144.9 0.2 1.5e-41 142.6 0.1 2.1 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain Roc PF08477.13 OAG33895.1 - 1e-34 119.3 0.4 2.9e-34 117.8 0.1 2.0 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAG33895.1 - 2e-15 56.7 0.1 9.5e-15 54.5 0.1 2.0 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OAG33895.1 - 0.00059 19.9 0.0 0.002 18.2 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OAG33895.1 - 0.0013 18.7 0.3 1.2 9.1 0.0 2.5 1 1 1 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 OAG33895.1 - 0.0019 17.7 0.1 0.0052 16.3 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OAG33895.1 - 0.0035 16.7 0.1 0.0065 15.9 0.1 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DUF2808 PF10989.8 OAG33895.1 - 0.0037 17.3 0.0 0.0095 15.9 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2808) SRPRB PF09439.10 OAG33895.1 - 0.0074 15.7 0.0 0.017 14.6 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_29 PF13555.6 OAG33895.1 - 0.053 13.3 0.0 0.14 11.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.29 OAG33895.1 - 0.063 13.7 0.1 3.6 8.0 0.0 3.0 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Big_3_2 PF12245.8 OAG33895.1 - 0.12 12.6 0.5 0.42 10.9 0.1 2.1 2 0 0 2 2 1 0 Bacterial Ig-like domain AAA_16 PF13191.6 OAG33895.1 - 0.13 12.7 0.0 0.33 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain DUF3357 PF11837.8 OAG33896.1 - 0.07 13.6 0.3 0.14 12.6 0.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) Iso_dh PF00180.20 OAG33902.1 - 1.7e-10 40.6 0.0 3.6e-07 29.7 0.0 2.0 1 1 1 2 2 2 2 Isocitrate/isopropylmalate dehydrogenase ThiF PF00899.21 OAG33903.1 - 0.00066 19.1 0.0 0.00067 19.1 0.0 1.2 1 0 0 1 1 1 1 ThiF family Sugar_tr PF00083.24 OAG33905.1 - 2e-14 53.3 1.0 3.4e-14 52.6 1.0 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter NAC PF01849.18 OAG33906.1 - 1 9.4 3.3 3.4 7.7 0.2 3.0 3 0 0 3 3 3 0 NAC domain FMO-like PF00743.19 OAG33911.1 - 7.8e-16 57.6 0.0 1.9e-10 39.8 0.0 3.2 2 2 1 3 3 3 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 OAG33911.1 - 8.4e-12 44.9 0.0 1.4e-08 34.3 0.0 2.2 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG33911.1 - 1.3e-10 41.0 0.1 2.1e-06 27.1 0.0 3.3 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 OAG33911.1 - 2.6e-10 40.4 0.0 7.4e-10 38.9 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 OAG33911.1 - 3.9e-09 36.2 0.5 2.3e-07 30.4 0.1 3.2 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAG33911.1 - 1.5e-05 24.4 0.1 0.00094 18.5 0.0 2.4 3 0 0 3 3 3 1 Thi4 family NAD_binding_9 PF13454.6 OAG33911.1 - 0.00031 20.8 0.0 0.062 13.3 0.0 3.0 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.24 OAG33911.1 - 0.0006 19.5 0.0 0.0042 16.7 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OAG33911.1 - 0.0084 15.2 0.0 0.016 14.3 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_7 PF13241.6 OAG33911.1 - 0.022 15.2 0.0 1.8 9.0 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding HI0933_like PF03486.14 OAG33911.1 - 0.026 13.2 0.1 0.049 12.3 0.1 1.4 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.27 OAG33911.1 - 0.038 14.6 0.2 14 6.4 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OAG33911.1 - 0.057 12.5 0.4 4 6.4 0.3 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A Malic_M PF03949.15 OAG33911.1 - 0.19 10.9 0.0 4.6 6.4 0.0 2.1 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain AlaDh_PNT_C PF01262.21 OAG33911.1 - 0.31 10.3 1.5 0.35 10.1 0.1 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain SnoaL_4 PF13577.6 OAG33912.1 - 2.5e-21 76.1 0.1 3.1e-21 75.8 0.1 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_2 PF12680.7 OAG33912.1 - 8.6e-05 23.1 0.0 0.00014 22.5 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like domain Lumazine_bd_2 PF12893.7 OAG33912.1 - 0.028 15.1 0.0 0.062 14.0 0.0 1.4 1 1 0 1 1 1 0 Putative lumazine-binding SnoaL_3 PF13474.6 OAG33912.1 - 0.058 13.7 0.0 0.092 13.0 0.0 1.3 1 1 0 1 1 1 0 SnoaL-like domain Abhydrolase_1 PF00561.20 OAG33913.1 - 1.1e-21 77.6 0.0 1.3e-18 67.6 0.1 2.4 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG33913.1 - 6e-19 69.5 5.5 1.2e-18 68.6 5.5 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG33913.1 - 1.7e-16 60.2 0.0 2.6e-16 59.6 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 CMD PF02627.20 OAG33913.1 - 6.4e-10 39.0 1.4 4.6e-09 36.2 0.0 2.7 3 0 0 3 3 3 1 Carboxymuconolactone decarboxylase family Thioesterase PF00975.20 OAG33913.1 - 0.001 19.2 0.1 0.0029 17.7 0.1 1.8 1 1 0 1 1 1 1 Thioesterase domain Ndr PF03096.14 OAG33913.1 - 0.015 14.0 0.0 0.022 13.5 0.0 1.2 1 0 0 1 1 1 0 Ndr family MFS_1 PF07690.16 OAG33914.1 - 4.6e-31 108.0 36.2 5.8e-31 107.7 36.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily S1FA PF04689.13 OAG33914.1 - 0.42 10.8 5.4 2.2 8.5 0.0 3.1 3 0 0 3 3 3 0 DNA binding protein S1FA MFS_1 PF07690.16 OAG33915.1 - 7e-24 84.4 18.2 8.7e-24 84.1 18.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.16 OAG33916.1 - 4.2e-41 141.1 32.5 4.6e-41 140.9 30.4 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG33916.1 - 2.3e-10 39.9 4.8 2.3e-10 39.9 4.8 2.9 4 0 0 4 4 4 1 Sugar (and other) transporter MFS_3 PF05977.13 OAG33916.1 - 1.5e-06 26.9 4.6 4e-06 25.5 4.6 1.6 1 0 0 1 1 1 1 Transmembrane secretion effector Sulfatase PF00884.23 OAG33917.1 - 6.3e-67 226.2 0.6 8.9e-67 225.7 0.6 1.2 1 0 0 1 1 1 1 Sulfatase DUF4976 PF16347.5 OAG33917.1 - 0.0061 16.8 0.1 0.019 15.2 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4976) Phosphodiest PF01663.22 OAG33917.1 - 0.24 11.0 4.3 9.9 5.6 4.3 3.0 1 1 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase bZIP_2 PF07716.15 OAG33918.1 - 9e-12 44.9 18.0 1.4e-11 44.3 18.0 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 OAG33918.1 - 9.3e-06 25.7 15.0 1.5e-05 25.0 15.0 1.3 1 0 0 1 1 1 1 bZIP transcription factor SHE3 PF17078.5 OAG33918.1 - 0.0016 18.2 3.4 0.0023 17.7 3.4 1.2 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 DUF3552 PF12072.8 OAG33918.1 - 0.0026 17.2 10.0 0.0033 16.9 10.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) SOGA PF11365.8 OAG33918.1 - 0.0084 17.2 3.0 0.014 16.5 3.0 1.3 1 0 0 1 1 1 1 Protein SOGA YabA PF06156.13 OAG33918.1 - 0.035 14.7 4.7 0.054 14.1 4.7 1.4 1 0 0 1 1 1 0 Initiation control protein YabA TSC22 PF01166.18 OAG33918.1 - 0.039 14.3 1.5 0.098 13.0 1.3 1.7 1 1 1 2 2 2 0 TSC-22/dip/bun family CBM-like PF14683.6 OAG33918.1 - 0.046 13.6 0.0 0.059 13.2 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide lyase family 4, domain III DUF4094 PF13334.6 OAG33918.1 - 0.089 13.2 1.5 0.15 12.5 1.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) XhlA PF10779.9 OAG33918.1 - 0.11 12.7 4.8 0.21 11.8 4.8 1.5 1 0 0 1 1 1 0 Haemolysin XhlA Jnk-SapK_ap_N PF09744.9 OAG33918.1 - 0.18 12.0 9.2 0.24 11.6 9.2 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 HSP70 PF00012.20 OAG33918.1 - 0.23 9.6 4.9 0.28 9.3 4.9 1.0 1 0 0 1 1 1 0 Hsp70 protein zf-CpG_bind_C PF12269.8 OAG33918.1 - 0.24 11.2 6.1 0.3 10.9 5.3 1.5 1 1 1 2 2 2 0 CpG binding protein zinc finger C terminal domain CMS1 PF14617.6 OAG33918.1 - 0.71 9.2 6.7 0.96 8.7 6.7 1.1 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit DivIC PF04977.15 OAG33918.1 - 7.6 6.4 9.2 4.3 7.2 7.0 1.7 1 1 1 2 2 2 0 Septum formation initiator FMO-like PF00743.19 OAG33919.1 - 3.2e-09 35.8 0.0 3.7e-08 32.3 0.0 2.0 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OAG33919.1 - 1.3e-07 31.7 0.2 6.9e-06 26.2 0.1 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAG33919.1 - 1.3e-07 31.2 0.1 2.5e-06 26.9 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG33919.1 - 2.3e-05 23.8 0.3 0.00015 21.1 0.3 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG33919.1 - 8.6e-05 21.8 0.0 0.0002 20.6 0.0 1.5 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 OAG33919.1 - 0.0036 17.3 0.1 0.17 11.9 0.0 3.0 3 0 0 3 3 3 1 FAD-NAD(P)-binding Shikimate_DH PF01488.20 OAG33919.1 - 0.0099 15.9 0.3 0.097 12.7 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 OAG33919.1 - 0.016 14.6 0.1 0.039 13.3 0.0 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ThiF PF00899.21 OAG33919.1 - 0.057 12.8 1.2 0.87 8.9 0.1 2.6 3 0 0 3 3 3 0 ThiF family DAO PF01266.24 OAG33919.1 - 8.1 5.9 7.3 8.5 5.8 1.7 3.0 3 1 0 3 3 3 0 FAD dependent oxidoreductase 4HBT PF03061.22 OAG33920.1 - 3.2e-07 30.6 0.0 4.9e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.6 OAG33920.1 - 0.038 14.1 0.1 0.059 13.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) MaoC_dehydratas PF01575.19 OAG33920.1 - 0.11 12.0 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 MaoC like domain FMO-like PF00743.19 OAG33922.1 - 4.6e-16 58.3 0.0 3.1e-15 55.6 0.0 2.1 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OAG33922.1 - 7.1e-15 55.0 0.0 5.3e-10 39.0 0.0 2.9 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAG33922.1 - 1.1e-12 47.8 0.2 4.6e-12 45.8 0.2 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG33922.1 - 2.6e-08 33.4 0.0 2.7e-05 23.5 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 OAG33922.1 - 2.2e-06 27.8 2.9 2.3e-06 27.7 0.2 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 OAG33922.1 - 3.7e-06 27.4 4.6 0.014 15.9 0.8 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 OAG33922.1 - 5.9e-05 22.5 2.8 0.0038 16.5 0.2 2.1 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 OAG33922.1 - 0.0001 22.1 1.8 0.0001 22.1 1.8 2.1 1 1 1 2 2 2 1 FAD dependent oxidoreductase 3HCDH_N PF02737.18 OAG33922.1 - 0.00069 19.6 0.4 0.0011 18.9 0.4 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 OAG33922.1 - 0.00091 19.3 0.0 1.3 9.1 0.0 2.5 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase FAD_oxidored PF12831.7 OAG33922.1 - 0.0038 16.6 0.0 0.0038 16.6 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 OAG33922.1 - 0.0038 17.2 0.6 0.057 13.4 0.1 2.6 3 0 0 3 3 3 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 OAG33922.1 - 0.0055 15.8 0.6 0.0092 15.1 0.6 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_7 PF13241.6 OAG33922.1 - 0.0077 16.7 0.0 0.44 11.0 0.0 2.3 2 0 0 2 2 2 1 Putative NAD(P)-binding NAD_binding_2 PF03446.15 OAG33922.1 - 0.079 13.1 0.7 0.19 11.9 0.1 1.8 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Amino_oxidase PF01593.24 OAG33922.1 - 0.08 12.2 0.0 0.28 10.4 0.0 1.8 1 1 1 2 2 2 0 Flavin containing amine oxidoreductase HI0933_like PF03486.14 OAG33922.1 - 0.15 10.7 2.8 0.1 11.3 0.3 1.9 3 0 0 3 3 3 0 HI0933-like protein 2-Hacid_dh_C PF02826.19 OAG33922.1 - 0.16 11.3 0.0 7.9 5.8 0.0 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PAP2 PF01569.21 OAG33923.1 - 1.4e-28 99.3 1.1 1.4e-28 99.3 1.1 1.6 2 0 0 2 2 2 1 PAP2 superfamily MNHE PF01899.16 OAG33923.1 - 0.014 15.1 0.3 1.5 8.6 0.1 2.4 2 1 0 2 2 2 0 Na+/H+ ion antiporter subunit Arg_tRNA_synt_N PF03485.16 OAG33923.1 - 0.043 14.4 0.1 0.12 13.0 0.1 1.7 1 0 0 1 1 1 0 Arginyl tRNA synthetase N terminal domain RseC_MucC PF04246.12 OAG33923.1 - 0.16 11.9 1.8 7.8 6.5 0.6 2.4 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC DUF5510 PF17629.2 OAG33923.1 - 1.1 9.3 3.3 1.1 9.2 0.4 2.3 2 1 0 2 2 2 0 Family of unknown function (DUF5510) Med7 PF05983.11 OAG33924.1 - 3.7e-43 147.9 5.0 5.8e-43 147.2 5.0 1.3 1 0 0 1 1 1 1 MED7 protein Lyase_1 PF00206.20 OAG33925.1 - 5.7e-24 85.1 0.0 1.1e-23 84.2 0.0 1.4 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 OAG33925.1 - 7.6e-14 52.0 0.0 2.1e-13 50.6 0.0 1.8 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus DEAD PF00270.29 OAG33926.1 - 1.3e-41 142.3 0.1 4.9e-41 140.4 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAG33926.1 - 1.4e-28 99.4 0.1 3.9e-28 98.0 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG33926.1 - 0.00054 20.0 0.0 0.0031 17.5 0.0 2.2 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 OAG33926.1 - 0.044 14.1 2.3 0.066 13.5 0.5 2.4 2 1 0 2 2 2 0 AAA domain Patatin PF01734.22 OAG33927.1 - 2.5e-19 70.3 0.0 1.9e-18 67.4 0.0 2.2 2 1 0 2 2 2 1 Patatin-like phospholipase ADH_zinc_N_2 PF13602.6 OAG33928.1 - 4.4e-26 92.5 1.7 5.4e-25 89.0 1.7 2.2 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 OAG33928.1 - 8e-16 58.2 0.4 1.8e-15 57.1 0.4 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG33928.1 - 0.003 17.4 0.0 0.044 13.7 0.0 2.6 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain Sporozoite_P67 PF05642.11 OAG33928.1 - 0.31 9.1 10.9 0.44 8.6 10.9 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Dicty_REP PF05086.12 OAG33928.1 - 1 7.2 2.8 1.3 6.9 2.8 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein PBCV_basic_adap PF08789.10 OAG33929.1 - 9.9 6.4 7.8 16 5.7 0.4 3.5 4 0 0 4 4 4 0 PBCV-specific basic adaptor domain NUDIX PF00293.28 OAG33930.1 - 1e-19 70.9 1.0 1.3e-19 70.5 1.0 1.2 1 0 0 1 1 1 1 NUDIX domain NDT80_PhoG PF05224.12 OAG33932.1 - 1.1e-12 48.6 0.0 2.8e-11 44.0 0.0 2.2 1 1 0 1 1 1 1 NDT80 / PhoG like DNA-binding family Phage_T7_tail PF03906.14 OAG33933.1 - 0.025 14.2 0.0 0.073 12.7 0.0 1.6 2 0 0 2 2 2 0 Phage T7 tail fibre protein MbtH PF03621.13 OAG33933.1 - 0.11 12.0 0.2 0.45 10.0 0.2 2.1 1 0 0 1 1 1 0 MbtH-like protein DUF2516 PF10724.9 OAG33935.1 - 0.0078 16.5 2.2 0.0078 16.5 2.2 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF2516) Protocadherin PF08374.11 OAG33935.1 - 0.21 11.5 0.1 0.31 11.0 0.1 1.2 1 0 0 1 1 1 0 Protocadherin Syndecan PF01034.20 OAG33935.1 - 9.5 6.2 6.4 0.52 10.3 0.6 1.9 2 0 0 2 2 2 0 Syndecan domain G-patch PF01585.23 OAG33936.1 - 6.3e-06 26.0 0.9 0.00048 20.0 0.0 2.5 2 0 0 2 2 2 1 G-patch domain CENP-N PF05238.13 OAG33936.1 - 0.064 12.6 6.9 0.11 11.8 6.9 1.3 1 0 0 1 1 1 0 Kinetochore protein CHL4 like Lin-8 PF03353.15 OAG33936.1 - 0.39 10.2 7.7 0.56 9.7 7.7 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SAGA-Tad1 PF12767.7 OAG33936.1 - 4.9 6.8 10.0 9.2 5.9 10.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Pinin_SDK_memA PF04696.13 OAG33936.1 - 6.5 6.8 23.2 0.14 12.2 13.0 2.5 3 0 0 3 3 3 0 pinin/SDK/memA/ protein conserved region Mannosyl_trans3 PF11051.8 OAG33937.1 - 1.3e-33 116.5 0.0 1.9e-33 116.0 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative DUF3589 PF12141.8 OAG33938.1 - 8.2e-70 235.8 0.0 1.3e-38 132.9 0.0 2.1 2 0 0 2 2 2 2 Beta-mannosyltransferases Acyl_transf_3 PF01757.22 OAG33939.1 - 1.6e-19 70.2 18.3 5.3e-19 68.5 18.3 1.8 1 1 0 1 1 1 1 Acyltransferase family Pkinase PF00069.25 OAG33940.1 - 5.2e-76 255.5 0.0 8.9e-76 254.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG33940.1 - 5.9e-38 130.6 0.0 8.4e-38 130.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 OAG33940.1 - 1.8e-16 60.3 0.0 3.9e-16 59.1 0.0 1.6 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.6 OAG33940.1 - 1.6e-09 37.5 0.0 6.1e-09 35.6 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 OAG33940.1 - 1.1e-06 27.7 0.0 1.1e-06 27.7 0.0 2.1 3 0 0 3 3 3 1 Fungal protein kinase Yop-YscD_cpl PF16697.5 OAG33940.1 - 2e-06 28.0 0.0 6.2e-06 26.4 0.0 1.8 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain Kdo PF06293.14 OAG33940.1 - 0.041 13.2 0.0 0.077 12.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 OAG33940.1 - 0.11 11.4 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase bZIP_1 PF00170.21 OAG33942.1 - 1.9e-06 27.8 3.0 1.9e-06 27.8 3.0 2.3 3 1 1 4 4 4 1 bZIP transcription factor HAP1_N PF04849.13 OAG33942.1 - 0.67 9.1 14.0 1 8.5 14.0 1.2 1 0 0 1 1 1 0 HAP1 N-terminal conserved region Presenilin PF01080.17 OAG33942.1 - 1.7 7.3 6.8 2.3 6.9 6.8 1.2 1 0 0 1 1 1 0 Presenilin V_ATPase_I PF01496.19 OAG33942.1 - 3.4 5.5 6.1 4.3 5.1 6.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Med3 PF11593.8 OAG33942.1 - 6.5 5.8 17.6 0.11 11.6 0.6 2.9 3 0 0 3 3 3 0 Mediator complex subunit 3 fungal bZIP_1 PF00170.21 OAG33943.1 - 2.3e-06 27.6 12.1 3.2e-06 27.2 12.1 1.2 1 0 0 1 1 1 1 bZIP transcription factor TMF_TATA_bd PF12325.8 OAG33943.1 - 0.0014 18.8 2.2 0.002 18.3 2.2 1.2 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding AKNA PF12443.8 OAG33943.1 - 0.018 15.7 3.1 0.02 15.6 2.0 1.7 1 1 0 1 1 1 0 AT-hook-containing transcription factor Band_3_cyto PF07565.13 OAG33943.1 - 0.02 14.7 1.4 0.028 14.2 1.4 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain HSP70 PF00012.20 OAG33943.1 - 0.027 12.7 0.2 0.035 12.3 0.2 1.0 1 0 0 1 1 1 0 Hsp70 protein ADIP PF11559.8 OAG33943.1 - 0.034 14.2 8.1 0.051 13.7 8.1 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF16 PF01519.16 OAG33943.1 - 0.049 14.1 1.0 0.075 13.5 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF16 UPF0242 PF06785.11 OAG33943.1 - 0.056 13.6 4.0 0.073 13.2 4.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF2400 PF09674.10 OAG33943.1 - 0.068 13.2 0.7 0.09 12.8 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) EMC3_TMCO1 PF01956.16 OAG33943.1 - 0.19 11.4 0.0 0.25 11.0 0.0 1.1 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like bZIP_2 PF07716.15 OAG33943.1 - 0.2 11.8 13.6 8.1 6.6 12.6 2.2 1 1 1 2 2 2 0 Basic region leucine zipper Csm1_N PF18504.1 OAG33943.1 - 0.21 12.0 3.4 1.3 9.4 1.3 2.3 1 1 1 2 2 2 0 Csm1 N-terminal domain CLZ PF16526.5 OAG33943.1 - 0.23 11.8 6.0 0.78 10.1 5.9 1.9 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels FAM76 PF16046.5 OAG33943.1 - 0.94 8.8 4.9 1.3 8.3 4.9 1.1 1 0 0 1 1 1 0 FAM76 protein IATP PF04568.12 OAG33943.1 - 1.1 9.7 5.6 1.3 9.4 4.4 1.8 1 1 1 2 2 2 0 Mitochondrial ATPase inhibitor, IATP T4SS PF07996.11 OAG33943.1 - 1.6 9.1 7.3 2.6 8.4 0.6 2.1 1 1 1 2 2 2 0 Type IV secretion system proteins ECH_1 PF00378.20 OAG33945.1 - 2.8e-43 148.0 0.0 3.4e-43 147.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAG33945.1 - 9.8e-28 97.6 0.1 4.4e-24 85.6 0.1 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase THF_DHG_CYH PF00763.23 OAG33946.1 - 1.8e-19 70.1 0.0 5.7e-19 68.5 0.0 1.9 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 OAG33946.1 - 9.2e-12 44.6 0.1 1.4e-08 34.2 0.0 2.7 2 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain OB_NTP_bind PF07717.16 OAG33947.1 - 1.1e-24 86.6 0.0 3.1e-24 85.1 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 OAG33947.1 - 2.2e-19 69.8 0.0 2.2e-19 69.8 0.0 3.6 3 2 0 3 3 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 OAG33947.1 - 2.5e-13 50.3 0.0 6.4e-13 49.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 OAG33947.1 - 1.5e-07 31.4 0.1 3.1e-07 30.3 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 OAG33947.1 - 2.7e-05 24.5 0.0 8.6e-05 22.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 OAG33947.1 - 3.7e-05 23.5 0.1 9.5e-05 22.2 0.1 1.7 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 OAG33947.1 - 4.1e-05 22.8 0.0 0.00012 21.2 0.0 1.8 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.6 OAG33947.1 - 7.1e-05 23.2 1.3 0.00015 22.1 0.1 2.1 2 0 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.6 OAG33947.1 - 0.018 15.2 0.1 0.076 13.1 0.0 2.1 3 0 0 3 3 2 0 Sigma-54 interaction domain AAA_23 PF13476.6 OAG33947.1 - 0.058 13.9 0.0 0.058 13.9 0.0 3.6 1 1 2 3 3 1 0 AAA domain SRP54 PF00448.22 OAG33947.1 - 0.096 12.3 0.2 0.27 10.8 0.2 1.9 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain cobW PF02492.19 OAG33947.1 - 0.12 11.9 0.5 3 7.4 0.2 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.27 OAG33947.1 - 0.17 12.4 0.2 0.17 12.4 0.2 2.9 2 1 1 3 3 3 0 ABC transporter AAA_14 PF13173.6 OAG33947.1 - 0.71 9.9 2.6 19 5.3 0.1 3.1 2 1 0 2 2 2 0 AAA domain ResIII PF04851.15 OAG33947.1 - 0.93 9.5 4.2 2.3 8.2 0.1 3.1 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit MMS19_C PF12460.8 OAG33948.1 - 4.2e-95 319.3 9.2 9.5e-92 308.3 6.3 3.3 3 0 0 3 3 3 2 RNAPII transcription regulator C-terminal MMS19_N PF14500.6 OAG33948.1 - 5.2e-94 314.7 0.3 3.3e-91 305.5 0.0 3.9 4 0 0 4 4 4 1 Dos2-interacting transcription regulator of RNA-Pol-II HEAT_2 PF13646.6 OAG33948.1 - 0.00028 21.2 8.6 0.24 11.8 0.2 6.0 7 1 0 7 7 7 2 HEAT repeats RTP1_C1 PF10363.9 OAG33948.1 - 0.0071 16.5 0.2 0.62 10.3 0.0 3.5 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 OAG33948.1 - 0.02 15.4 6.5 1.3 9.6 0.1 5.1 6 1 1 7 7 7 0 HEAT-like repeat HEAT PF02985.22 OAG33948.1 - 0.051 13.9 5.1 43 4.7 0.0 5.6 5 0 0 5 5 5 0 HEAT repeat RIX1 PF08167.12 OAG33948.1 - 0.12 12.1 3.4 7.1 6.3 0.2 4.2 4 0 0 4 4 4 0 rRNA processing/ribosome biogenesis Adaptin_N PF01602.20 OAG33948.1 - 0.63 8.5 6.2 6.4 5.2 0.3 4.6 5 1 0 6 6 6 0 Adaptin N terminal region NMT1 PF09084.11 OAG33949.1 - 9.1e-11 42.1 0.0 2.8e-10 40.5 0.0 1.8 1 1 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 OAG33949.1 - 8.8e-05 22.3 0.0 0.0012 18.5 0.0 2.1 2 0 0 2 2 2 1 NMT1-like family SBP_bac_3 PF00497.20 OAG33949.1 - 0.01 15.2 0.0 0.034 13.6 0.0 1.8 1 1 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 Phosphonate-bd PF12974.7 OAG33949.1 - 0.079 12.5 0.0 0.16 11.6 0.0 1.5 1 1 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein MHYT PF03707.16 OAG33950.1 - 3.7e-28 97.5 17.6 9.2e-12 45.0 0.1 4.6 4 0 0 4 4 4 3 Bacterial signalling protein N terminal repeat HATPase_c PF02518.26 OAG33950.1 - 5.8e-23 81.5 0.0 1.2e-22 80.6 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 OAG33950.1 - 2.4e-21 76.0 0.6 5.6e-21 74.8 0.6 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 OAG33950.1 - 3.6e-13 49.3 0.7 1.3e-12 47.6 0.7 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.6 OAG33950.1 - 0.0032 17.3 0.0 0.01 15.8 0.0 1.9 1 0 0 1 1 1 1 GHKL domain HATPase_c_2 PF13581.6 OAG33950.1 - 0.076 13.0 0.0 0.21 11.6 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain AIM24 PF01987.17 OAG33951.1 - 1e-50 172.3 0.3 1.3e-50 172.0 0.3 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 eIF-5_eIF-2B PF01873.17 OAG33952.1 - 7.2e-42 142.0 0.7 1.3e-41 141.2 0.7 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 DUF1509 PF07420.11 OAG33952.1 - 0.012 14.6 2.2 0.017 14.1 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) TF_Zn_Ribbon PF08271.12 OAG33952.1 - 0.11 12.0 0.4 0.25 10.9 0.4 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding zf-HYPF PF07503.12 OAG33952.1 - 1.8 8.4 5.1 19 5.2 3.0 2.7 2 1 1 3 3 3 0 HypF finger Arc_trans_TRASH PF08394.10 OAG33952.1 - 1.9 8.9 7.9 1.6 9.2 0.3 3.0 2 1 1 3 3 3 0 Archaeal TRASH domain H-K_ATPase_N PF09040.11 OAG33952.1 - 4.8 7.7 11.0 2.1 8.9 2.2 2.7 2 0 0 2 2 2 0 Gastric H+/K+-ATPase, N terminal domain F-box-like PF12937.7 OAG33954.1 - 8.7e-06 25.5 0.2 2.8e-05 23.9 0.2 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAG33954.1 - 5.9e-05 22.8 4.6 0.0014 18.5 4.6 2.5 1 1 0 1 1 1 1 F-box domain DNA_binding_1 PF01035.20 OAG33955.1 - 7.9e-24 83.6 0.0 5.2e-23 81.0 0.0 2.2 2 0 0 2 2 2 1 6-O-methylguanine DNA methyltransferase, DNA binding domain TFIIF_alpha PF05793.12 OAG33955.1 - 0.32 9.6 6.2 0.42 9.1 6.2 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) MRC1 PF09444.10 OAG33956.1 - 1.4e-35 122.9 25.2 1.4e-35 122.9 25.2 7.9 5 2 3 8 8 8 1 MRC1-like domain AMP-binding PF00501.28 OAG33957.1 - 4.4e-76 256.2 0.3 5.4e-76 255.9 0.3 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG33957.1 - 6.1e-14 52.8 0.2 1.4e-13 51.6 0.2 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain zf-CCHC PF00098.23 OAG33958.1 - 1.9e-49 163.6 85.0 1.8e-07 30.9 2.0 10.2 10 0 0 10 10 10 10 Zinc knuckle zf-CCHC_2 PF13696.6 OAG33958.1 - 9.8e-14 50.9 65.3 0.022 14.6 0.1 10.2 10 0 0 10 10 10 8 Zinc knuckle zf-CCHC_3 PF13917.6 OAG33958.1 - 8e-08 32.1 62.6 0.11 12.4 0.9 9.9 4 2 6 10 10 10 7 Zinc knuckle zf-C2H2_10 PF16588.5 OAG33958.1 - 0.00024 20.7 2.0 0.00024 20.7 2.0 7.0 6 1 1 7 7 7 2 C2H2 zinc-finger zf-CCHC_4 PF14392.6 OAG33958.1 - 0.00038 20.1 54.3 0.19 11.5 0.6 10.0 10 0 0 10 10 10 6 Zinc knuckle zf-CCHC_6 PF15288.6 OAG33958.1 - 0.0031 17.3 1.8 0.0031 17.3 1.8 9.2 4 2 6 10 10 10 5 Zinc knuckle adh_short PF00106.25 OAG33959.1 - 2.9e-08 33.4 0.0 7.6e-08 32.0 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG33959.1 - 1.3e-06 28.2 0.0 3.4e-06 26.8 0.0 1.6 2 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase RmlD_sub_bind PF04321.17 OAG33959.1 - 0.0024 17.0 0.0 0.0034 16.5 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain F420_oxidored PF03807.17 OAG33959.1 - 0.015 15.9 0.1 0.037 14.6 0.1 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ECH_1 PF00378.20 OAG33960.1 - 2.4e-36 125.3 0.0 3.5e-36 124.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAG33960.1 - 8.9e-15 55.0 0.0 1.1e-14 54.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Mur_ligase_M PF08245.12 OAG33961.1 - 2.8e-05 24.2 0.0 7.1e-05 22.9 0.0 1.6 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 OAG33961.1 - 0.0001 22.5 0.0 0.00022 21.4 0.0 1.6 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain DUF1168 PF06658.12 OAG33962.1 - 6.2e-37 126.5 15.3 8.7e-37 126.0 15.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) DUF966 PF06136.13 OAG33962.1 - 0.061 13.0 6.6 0.069 12.9 6.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) PPL5 PF18168.1 OAG33962.1 - 0.12 11.6 5.3 0.16 11.2 5.3 1.1 1 0 0 1 1 1 0 Prim-pol family 5 Zip PF02535.22 OAG33962.1 - 1 8.5 2.1 1.3 8.2 2.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter CDC45 PF02724.14 OAG33962.1 - 4.1 5.6 15.7 5 5.3 15.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 OAG33962.1 - 4.2 6.0 9.2 5.1 5.8 9.2 1.1 1 0 0 1 1 1 0 Presenilin Peptidase_S49_N PF08496.10 OAG33962.1 - 5.9 6.9 7.2 9.8 6.2 7.2 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal adh_short PF00106.25 OAG33963.1 - 1.2e-32 112.9 0.0 1.8e-32 112.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG33963.1 - 3.4e-22 79.2 0.0 4.9e-22 78.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 OAG33963.1 - 6.6e-07 29.0 0.0 9e-07 28.5 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) KR PF08659.10 OAG33963.1 - 5.9e-06 26.3 0.8 8.3e-05 22.6 0.8 2.1 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG33963.1 - 0.0026 17.3 0.1 0.0044 16.5 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 OAG33963.1 - 0.026 13.8 0.0 0.043 13.1 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3Beta_HSD PF01073.19 OAG33963.1 - 0.042 12.9 0.1 0.06 12.3 0.1 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DFP PF04127.15 OAG33963.1 - 0.042 13.7 0.0 0.073 12.9 0.0 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein PAP_assoc PF03828.19 OAG33964.1 - 3.8e-19 68.7 0.2 1.5e-18 66.8 0.0 2.2 2 0 0 2 2 2 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 OAG33964.1 - 4.6e-05 23.6 0.0 0.00012 22.3 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain TFIIF_alpha PF05793.12 OAG33965.1 - 7e-05 21.6 41.4 7e-05 21.6 41.4 2.2 1 1 1 2 2 2 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) muHD PF10291.9 OAG33966.1 - 3.2e-67 226.8 0.0 4.5e-67 226.3 0.0 1.2 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.23 OAG33966.1 - 4.4e-09 36.5 0.4 1.6e-08 34.7 0.0 2.2 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain Adap_comp_sub PF00928.21 OAG33966.1 - 5.2e-06 26.0 0.0 0.00049 19.6 0.0 2.2 2 0 0 2 2 2 2 Adaptor complexes medium subunit family BAR_3 PF16746.5 OAG33966.1 - 0.031 14.0 0.1 0.053 13.2 0.1 1.3 1 0 0 1 1 1 0 BAR domain of APPL family Laminin_II PF06009.12 OAG33966.1 - 0.06 13.4 0.3 0.18 11.8 0.3 1.8 1 0 0 1 1 1 0 Laminin Domain II Pkinase PF00069.25 OAG33967.1 - 3.4e-42 144.6 0.0 4.8e-42 144.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG33967.1 - 6.7e-21 74.7 0.0 9.8e-21 74.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OAG33967.1 - 1.7e-05 24.9 0.4 0.0033 17.4 0.0 2.3 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OAG33967.1 - 0.0012 17.7 0.0 0.0022 16.8 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 OAG33967.1 - 0.0035 16.7 0.0 0.0057 16.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OAG33967.1 - 0.0053 16.1 0.0 0.014 14.8 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 OAG33967.1 - 0.066 12.8 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase EFG_II PF14492.6 OAG33967.1 - 0.11 12.6 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Elongation Factor G, domain II SH3_9 PF14604.6 OAG33968.1 - 3.3e-11 42.9 0.0 5.5e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 OAG33968.1 - 5.4e-08 32.3 0.0 8.3e-08 31.7 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 OAG33968.1 - 1.2e-06 28.1 0.0 2e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain VSP PF03302.13 OAG33968.1 - 2.1e-06 26.9 0.9 3.4e-06 26.2 0.9 1.3 1 0 0 1 1 1 1 Giardia variant-specific surface protein dCMP_cyt_deam_1 PF00383.23 OAG33970.1 - 7.5e-09 35.4 0.0 9.5e-09 35.1 0.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 OAG33970.1 - 1.8e-06 27.8 0.3 3.7e-06 26.8 0.3 1.6 1 1 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 OAG33970.1 - 0.043 13.9 0.0 0.057 13.5 0.0 1.3 1 0 0 1 1 1 0 Bd3614-like deaminase NAD1 PF18778.1 OAG33970.1 - 0.23 11.5 1.2 2.6 8.1 1.2 2.0 1 1 0 1 1 1 0 Novel AID APOBEC clade 1 APOBEC2 PF18772.1 OAG33970.1 - 0.46 10.5 1.3 6.9 6.7 1.3 2.0 1 1 0 1 1 1 0 APOBEC2 GST_C_3 PF14497.6 OAG33972.1 - 2.4e-09 37.3 0.0 3.6e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 OAG33972.1 - 1.1e-07 32.2 0.0 1.8e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OAG33972.1 - 1.6e-07 31.4 0.0 2.4e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OAG33972.1 - 4.3e-07 29.9 0.0 8.7e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 OAG33972.1 - 6.8e-07 29.5 0.0 1.1e-06 28.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OAG33972.1 - 3.7e-05 23.9 0.0 5.9e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 OAG33972.1 - 0.00075 19.2 0.0 0.0014 18.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Syntaxin-5_N PF11416.8 OAG33972.1 - 0.065 12.5 0.8 0.12 11.6 0.8 1.4 1 0 0 1 1 1 0 Syntaxin-5 N-terminal, Sly1p-binding domain adh_short_C2 PF13561.6 OAG33973.1 - 3.6e-56 190.4 0.2 5.8e-56 189.7 0.2 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG33973.1 - 4.8e-50 169.7 0.3 6.2e-50 169.4 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG33973.1 - 4.6e-15 56.0 0.1 8.8e-15 55.1 0.1 1.4 2 0 0 2 2 2 1 KR domain CABS1 PF15367.6 OAG33973.1 - 0.0076 15.4 0.0 0.01 15.0 0.0 1.1 1 0 0 1 1 1 1 Calcium-binding and spermatid-specific protein 1 THF_DHG_CYH_C PF02882.19 OAG33973.1 - 0.075 12.4 0.2 0.67 9.3 0.0 2.4 2 1 1 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.21 OAG33973.1 - 0.13 11.8 0.1 0.34 10.3 0.1 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 OAG33973.1 - 0.14 11.2 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Pkinase PF00069.25 OAG33975.1 - 3.2e-09 36.6 0.0 1.1e-08 34.8 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.23 OAG33975.1 - 0.0092 15.9 0.1 0.013 15.4 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 OAG33975.1 - 0.025 13.8 0.0 0.053 12.8 0.0 1.6 1 1 0 1 1 1 0 Protein tyrosine kinase Kdo PF06293.14 OAG33975.1 - 0.054 12.9 0.1 0.075 12.4 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TPR_12 PF13424.6 OAG33976.1 - 1.1e-27 96.1 8.8 2.7e-12 46.8 5.8 3.0 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.6 OAG33976.1 - 9.8e-27 92.0 5.1 2.3e-08 33.7 0.1 3.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 OAG33976.1 - 2.5e-08 33.4 0.3 0.00022 21.1 0.3 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 OAG33976.1 - 8.5e-08 31.7 0.3 0.00018 21.2 0.2 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 OAG33976.1 - 4.8e-07 29.3 3.1 0.0039 17.1 0.6 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 OAG33976.1 - 6.4e-07 29.1 0.1 0.0026 17.8 0.1 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_4 PF07721.14 OAG33976.1 - 7.6e-06 26.1 0.4 0.01 16.4 0.9 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 OAG33976.1 - 4.2e-05 24.1 2.8 0.012 16.3 3.5 2.9 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 OAG33976.1 - 5e-05 23.4 0.2 1.3 9.6 0.1 3.6 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_MalT PF17874.1 OAG33976.1 - 0.00014 21.4 1.7 0.00026 20.5 1.7 1.5 1 1 0 1 1 1 1 MalT-like TPR region TPR_14 PF13428.6 OAG33976.1 - 0.00022 21.7 4.8 0.0024 18.6 1.2 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_5 PF12688.7 OAG33976.1 - 0.00027 21.2 0.5 0.00039 20.6 0.5 1.3 1 0 0 1 1 1 1 Tetratrico peptide repeat PPR PF01535.20 OAG33976.1 - 0.0016 18.6 0.4 1.7 9.1 0.0 3.1 3 1 0 3 3 3 1 PPR repeat TPR_19 PF14559.6 OAG33976.1 - 0.026 15.0 0.2 2.2 8.8 0.5 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 OAG33976.1 - 0.16 11.7 0.3 0.56 9.9 0.1 2.0 2 0 0 2 2 2 0 TPR repeat 4HB_MCP_1 PF12729.7 OAG33976.1 - 0.16 11.5 0.1 0.4 10.2 0.1 1.6 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction Prok-RING_2 PF14445.6 OAG33977.1 - 0.033 14.4 0.4 7.7 6.8 0.0 2.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 2 F-box-like PF12937.7 OAG33977.1 - 0.12 12.3 0.2 0.29 11.1 0.2 1.7 1 0 0 1 1 1 0 F-box-like ADH_N PF08240.12 OAG33978.1 - 8.9e-09 35.2 0.1 2.1e-08 34.0 0.1 1.6 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 OAG33978.1 - 8.5e-06 26.9 0.0 2.4e-05 25.4 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FpoO PF10621.9 OAG33980.1 - 0.041 14.2 0.0 0.065 13.5 0.0 1.3 1 0 0 1 1 1 0 F420H2 dehydrogenase subunit FpoO DUF2381 PF09544.10 OAG33980.1 - 0.074 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2381) Pkinase PF00069.25 OAG33982.1 - 1.1e-15 57.7 0.1 3.5e-15 56.1 0.1 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG33982.1 - 1.6e-14 53.9 0.0 5.1e-13 48.9 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OAG33982.1 - 0.044 13.7 0.3 0.089 12.7 0.3 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family Hydrolase_4 PF12146.8 OAG33984.1 - 1.7e-11 43.9 0.0 5.2e-11 42.3 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 AXE1 PF05448.12 OAG33984.1 - 2.4e-10 39.6 0.1 7.4e-09 34.7 0.0 2.2 2 1 0 2 2 2 1 Acetyl xylan esterase (AXE1) Peptidase_S15 PF02129.18 OAG33984.1 - 1.1e-08 35.0 0.0 1.9e-08 34.2 0.0 1.4 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.7 OAG33984.1 - 5.1e-07 30.5 0.1 6.4e-07 30.2 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 OAG33984.1 - 2e-06 27.5 0.1 0.00016 21.2 0.0 2.1 1 1 1 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 OAG33984.1 - 5e-05 23.1 0.4 0.0087 15.7 0.2 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold DUF1100 PF06500.11 OAG33984.1 - 0.00032 19.6 0.0 0.00043 19.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Esterase PF00756.20 OAG33984.1 - 0.00073 19.3 0.0 0.0017 18.1 0.0 1.8 1 1 0 1 1 1 1 Putative esterase BAAT_C PF08840.11 OAG33984.1 - 0.056 13.4 0.0 0.11 12.4 0.0 1.6 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_3 PF07859.13 OAG33984.1 - 0.08 12.8 0.0 0.15 11.9 0.0 1.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold HSP9_HSP12 PF04119.12 OAG33985.1 - 2.1e-24 85.6 19.7 3.8e-24 84.8 7.6 3.5 2 1 2 4 4 4 1 Heat shock protein 9/12 Apolipoprotein PF01442.18 OAG33985.1 - 0.0064 16.4 12.3 0.015 15.2 12.3 1.6 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF883 PF05957.13 OAG33985.1 - 0.008 16.8 5.6 0.008 16.8 5.6 2.8 1 1 2 3 3 3 2 Bacterial protein of unknown function (DUF883) ApoLp-III PF07464.11 OAG33985.1 - 0.013 15.6 18.5 0.049 13.7 18.5 1.9 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) MHB PF16525.5 OAG33985.1 - 0.09 13.0 4.1 0.26 11.6 4.1 1.8 1 0 0 1 1 1 0 Haemophore, haem-binding CorA PF01544.18 OAG33985.1 - 0.22 10.8 0.5 0.28 10.5 0.5 1.3 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein YtxH PF12732.7 OAG33985.1 - 0.51 10.9 19.7 1.8e+04 -5.1 19.7 3.6 1 1 0 1 1 0 0 YtxH-like protein ZYG-11_interact PF05884.12 OAG33985.1 - 0.9 8.9 6.5 1.1 8.6 6.5 1.1 1 0 0 1 1 1 0 Interactor of ZYG-11 Tape_meas_lam_C PF09718.10 OAG33985.1 - 1.3 9.2 18.1 1.3 9.2 2.3 3.6 1 1 2 3 3 3 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) Ndc1_Nup PF09531.10 OAG33985.1 - 5.6 5.5 16.1 6.5 5.3 16.1 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Plasmodium_Vir PF05795.11 OAG33985.1 - 9.8 5.5 10.4 11 5.3 10.4 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein CRAL_TRIO PF00650.20 OAG33986.1 - 4.1e-14 52.6 0.0 6.3e-14 52.0 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 OAG33986.1 - 0.0038 17.4 0.1 0.0059 16.8 0.1 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.15 OAG33986.1 - 0.018 15.2 0.0 0.041 14.1 0.0 1.6 1 0 0 1 1 1 0 CRAL/TRIO, N-terminal domain LIG3_BRCT PF16759.5 OAG33986.1 - 0.12 12.7 0.0 0.28 11.5 0.0 1.6 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain DNA_gyraseB_C PF00986.21 OAG33986.1 - 0.12 12.5 0.1 4.2 7.6 0.2 2.3 2 0 0 2 2 2 0 DNA gyrase B subunit, carboxyl terminus PRCC PF10253.9 OAG33986.1 - 0.7 10.7 3.7 0.96 10.2 3.7 1.3 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting GATA PF00320.27 OAG33987.1 - 4.1e-16 58.3 2.5 8.5e-16 57.3 2.5 1.6 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.10 OAG33987.1 - 7.3e-12 44.9 4.1 1.3e-11 44.1 4.1 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) AreA_N PF07573.11 OAG33987.1 - 4.2e-05 24.1 3.5 4.2e-05 24.1 3.5 5.1 5 2 1 6 6 6 1 Nitrogen regulatory protein AreA N terminus Robl_LC7 PF03259.17 OAG33988.1 - 0.015 15.1 1.3 0.82 9.5 0.0 2.6 3 0 0 3 3 3 0 Roadblock/LC7 domain Ipi1_N PF12333.8 OAG33989.1 - 5e-23 81.6 0.0 7.5e-23 81.1 0.0 1.3 1 0 0 1 1 1 1 Rix1 complex component involved in 60S ribosome maturation Amino_oxidase PF01593.24 OAG33990.1 - 1.4e-48 166.4 0.0 1.6e-48 166.1 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OAG33990.1 - 1.3e-11 44.5 0.0 2.7e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 OAG33990.1 - 6.8e-07 28.7 0.1 1e-06 28.1 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 OAG33990.1 - 9e-05 22.0 0.1 0.00013 21.4 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 OAG33990.1 - 0.00016 21.0 0.0 0.00028 20.2 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 OAG33990.1 - 0.00032 20.1 0.0 0.02 14.1 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAG33990.1 - 0.00048 19.0 0.0 0.001 17.9 0.0 1.5 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.14 OAG33990.1 - 0.0037 16.6 0.0 0.0063 15.8 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAG33990.1 - 0.0061 16.2 0.0 0.0099 15.5 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 OAG33990.1 - 0.024 13.7 0.1 0.072 12.2 0.1 1.8 2 1 0 2 2 2 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 OAG33990.1 - 0.026 13.6 0.2 0.17 10.9 0.1 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox PF00070.27 OAG33990.1 - 0.079 13.5 0.1 0.18 12.4 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AXE1 PF05448.12 OAG33992.1 - 2.4e-11 42.9 0.0 1.5e-06 27.1 0.0 3.0 3 0 0 3 3 3 2 Acetyl xylan esterase (AXE1) Abhydrolase_6 PF12697.7 OAG33992.1 - 5.4e-07 30.4 0.0 6.9e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAG33992.1 - 1.9e-06 27.8 0.0 7.2e-06 25.8 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 OAG33992.1 - 4.6e-06 26.4 0.0 5e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 OAG33992.1 - 5.5e-05 22.7 0.0 0.00028 20.4 0.0 1.9 2 0 0 2 2 2 1 Prolyl oligopeptidase family BAAT_C PF08840.11 OAG33992.1 - 0.00017 21.6 0.0 0.00041 20.3 0.0 1.8 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Hydrolase_4 PF12146.8 OAG33992.1 - 0.01 15.1 0.0 0.023 14.0 0.0 1.5 1 1 0 1 1 1 0 Serine aminopeptidase, S33 DLH PF01738.18 OAG33992.1 - 0.087 12.4 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 Dienelactone hydrolase family GST_N_2 PF13409.6 OAG33993.1 - 1.8e-05 24.9 0.0 5.7e-05 23.3 0.0 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 OAG33993.1 - 5.8e-05 23.4 0.0 0.00017 21.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DUF2236 PF09995.9 OAG33993.1 - 0.0035 17.6 0.2 0.0054 16.9 0.2 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) GST_C_2 PF13410.6 OAG33993.1 - 0.0038 17.2 0.2 0.014 15.4 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain p450 PF00067.22 OAG33995.1 - 1.9e-16 59.8 0.0 1.4e-09 37.2 0.0 2.8 2 2 0 2 2 2 2 Cytochrome P450 RNA12 PF10443.9 OAG33996.1 - 1.7e-169 564.3 1.5 4.1e-169 563.0 1.5 1.6 1 1 0 1 1 1 1 RNA12 protein RRM_1 PF00076.22 OAG33996.1 - 7.6e-06 25.7 0.0 5.4e-05 22.9 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ATPase_2 PF01637.18 OAG33996.1 - 2.2e-05 24.5 0.1 0.00034 20.6 0.0 2.6 2 1 0 2 2 2 1 ATPase domain predominantly from Archaea DUF2487 PF10673.9 OAG33996.1 - 0.0061 16.6 0.0 0.014 15.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2487) DUF3128 PF11326.8 OAG33997.1 - 1.9e-26 92.2 6.0 1.9e-26 92.2 6.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3128) NRN1 PF15056.6 OAG33997.1 - 0.074 13.2 2.6 14 5.9 2.7 2.4 1 1 1 2 2 2 0 Neuritin protein family DUF5321 PF17254.2 OAG33997.1 - 0.13 11.7 0.1 0.13 11.7 0.1 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5321) Alanine_zipper PF11839.8 OAG33998.1 - 0.037 14.4 2.9 0.037 14.4 2.9 2.5 3 0 0 3 3 3 0 Alanine-zipper, major outer membrane lipoprotein Prefoldin PF02996.17 OAG33998.1 - 0.068 13.1 2.9 0.87 9.5 0.4 2.9 2 1 1 3 3 3 0 Prefoldin subunit Menin PF05053.13 OAG33998.1 - 3 6.1 8.8 3.7 5.8 8.8 1.1 1 0 0 1 1 1 0 Menin DivIC PF04977.15 OAG33998.1 - 4.1 7.2 6.2 0.96 9.3 2.6 1.8 2 0 0 2 2 2 0 Septum formation initiator NmrA PF05368.13 OAG34000.1 - 1.6e-16 60.6 0.0 5.8e-16 58.8 0.0 1.7 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG34000.1 - 6.8e-15 55.4 0.0 1.2e-14 54.6 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 OAG34000.1 - 3.1e-09 37.2 0.0 5e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 OAG34000.1 - 1.2e-06 28.2 0.0 2e-05 24.2 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 OAG34000.1 - 0.00023 20.5 0.2 0.00037 19.8 0.2 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DapB_N PF01113.20 OAG34000.1 - 0.0011 19.1 0.0 0.0022 18.1 0.0 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus adh_short PF00106.25 OAG34000.1 - 0.0035 16.8 0.0 0.0059 16.1 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Semialdhyde_dh PF01118.24 OAG34000.1 - 0.0056 17.1 0.0 0.0093 16.4 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.17 OAG34000.1 - 0.0058 15.8 0.0 0.0094 15.1 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain F420_oxidored PF03807.17 OAG34000.1 - 0.016 15.8 0.1 0.036 14.7 0.1 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent CbiJ PF02571.14 OAG34000.1 - 0.02 14.4 0.2 0.031 13.8 0.2 1.2 1 0 0 1 1 1 0 Precorrin-6x reductase CbiJ/CobK 3HCDH_N PF02737.18 OAG34000.1 - 0.049 13.5 0.3 0.14 12.0 0.3 1.8 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain LytR_C PF13399.6 OAG34000.1 - 0.062 14.3 0.1 0.5 11.4 0.1 2.1 2 0 0 2 2 2 0 LytR cell envelope-related transcriptional attenuator PGM_PMM_II PF02879.16 OAG34000.1 - 0.12 13.0 0.0 2.6 8.7 0.0 2.4 2 0 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II DIOX_N PF14226.6 OAG34001.1 - 3.4e-31 108.4 0.0 5.7e-31 107.7 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OAG34001.1 - 4.3e-15 56.0 0.0 8.3e-15 55.1 0.0 1.5 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily EXS PF03124.14 OAG34002.1 - 1.3e-94 317.2 38.1 1.7e-94 316.9 38.1 1.1 1 0 0 1 1 1 1 EXS family SPX PF03105.19 OAG34002.1 - 2.6e-58 198.8 10.5 2.6e-58 198.8 10.5 2.8 2 1 0 2 2 2 1 SPX domain DARPP-32 PF05395.12 OAG34002.1 - 0.0035 17.6 5.0 0.0087 16.3 5.0 1.6 1 0 0 1 1 1 1 Protein phosphatase inhibitor 1/DARPP-32 ABM PF03992.16 OAG34003.1 - 0.0011 19.1 0.0 0.0013 18.8 0.0 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase FemAB_like PF04339.12 OAG34003.1 - 0.075 12.1 0.1 0.084 12.0 0.1 1.0 1 0 0 1 1 1 0 Peptidogalycan biosysnthesis/recognition Roughex PF06020.11 OAG34003.1 - 0.089 11.9 0.0 0.1 11.7 0.0 1.0 1 0 0 1 1 1 0 Drosophila roughex protein Molybdopterin PF00384.22 OAG34004.1 - 2e-68 231.4 0.0 2.1e-66 224.7 0.0 2.4 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fer2_4 PF13510.6 OAG34004.1 - 2.8e-20 72.2 0.1 6.2e-20 71.0 0.1 1.6 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.9 OAG34004.1 - 5.3e-17 61.1 0.2 5.3e-17 61.1 0.2 1.9 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region NADH_dhqG_C PF09326.11 OAG34004.1 - 8.8e-17 61.5 0.0 2e-16 60.4 0.0 1.7 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit G, C-terminal Fer2 PF00111.27 OAG34004.1 - 1.2e-08 34.7 0.5 1.2e-08 34.7 0.5 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Lyx_isomer PF07385.12 OAG34004.1 - 0.084 12.1 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 D-lyxose isomerase TPP_enzyme_M PF00205.22 OAG34004.1 - 0.12 12.1 0.0 0.6 9.9 0.0 2.2 3 0 0 3 3 3 0 Thiamine pyrophosphate enzyme, central domain FAD_binding_3 PF01494.19 OAG34005.1 - 4.8e-21 75.4 0.0 1.4e-20 73.9 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 OAG34005.1 - 4.7e-06 25.9 0.1 0.0081 15.3 0.1 2.5 2 1 0 2 2 2 2 Lycopene cyclase protein DAO PF01266.24 OAG34005.1 - 2.7e-05 23.9 0.1 0.0014 18.2 0.0 2.2 1 1 1 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAG34005.1 - 4.5e-05 23.6 0.0 0.0001 22.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 OAG34005.1 - 0.00034 19.9 0.0 0.00059 19.2 0.0 1.2 1 0 0 1 1 1 1 Thi4 family SE PF08491.10 OAG34005.1 - 0.00036 19.7 0.0 0.0054 15.8 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase NAD_binding_9 PF13454.6 OAG34005.1 - 0.0017 18.3 0.0 0.0051 16.8 0.0 1.8 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 OAG34005.1 - 0.044 13.0 0.0 0.1 11.8 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG34005.1 - 0.047 12.9 0.0 0.083 12.1 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TPR_7 PF13176.6 OAG34005.1 - 0.095 12.8 0.6 2.2 8.5 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat K_oxygenase PF13434.6 OAG34005.1 - 0.14 11.3 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) TPR_2 PF07719.17 OAG34005.1 - 1.2 9.4 3.5 8.7 6.7 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Arylsulfotran_2 PF14269.6 OAG34006.1 - 2.6e-58 197.7 0.5 4.7e-58 196.9 0.5 1.3 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 OAG34006.1 - 3.7e-11 42.5 0.8 3.3e-09 36.1 0.8 2.4 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Methyltransf_23 PF13489.6 OAG34007.1 - 9.1e-18 64.6 0.0 1.4e-17 64.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG34007.1 - 1.3e-12 48.3 0.0 2.6e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG34007.1 - 2.4e-08 34.5 0.0 7.2e-08 33.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG34007.1 - 1.6e-07 31.2 0.0 1.2e-06 28.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG34007.1 - 1.2e-06 29.2 0.0 5.4e-06 27.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 OAG34007.1 - 2.4e-06 27.1 0.0 3.5e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase FtsJ PF01728.19 OAG34007.1 - 0.00044 20.4 0.0 0.0023 18.1 0.0 2.0 1 1 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.14 OAG34007.1 - 0.0094 15.5 0.0 0.025 14.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 OAG34007.1 - 0.016 14.7 0.0 0.059 12.8 0.0 1.9 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_2 PF00891.18 OAG34007.1 - 0.049 12.9 0.0 0.07 12.4 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_16 PF10294.9 OAG34007.1 - 0.068 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase PrmA PF06325.13 OAG34007.1 - 0.2 11.0 0.0 0.32 10.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) p450 PF00067.22 OAG34008.1 - 3.3e-50 171.2 0.0 4.4e-50 170.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PRP1_N PF06424.12 OAG34009.1 - 1.4 9.3 12.3 3.1 8.2 6.3 2.9 2 1 0 2 2 2 0 PRP1 splicing factor, N-terminal Not3 PF04065.15 OAG34010.1 - 1.3e-78 263.6 25.1 1.3e-78 263.6 25.1 1.6 2 0 0 2 2 2 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 OAG34010.1 - 7.4e-41 139.3 16.7 1.8e-40 138.1 16.7 1.7 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family DUF2373 PF10180.9 OAG34010.1 - 0.013 15.3 4.6 0.035 14.0 4.6 1.7 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2373) Frankia_peptide PF14407.6 OAG34010.1 - 0.051 13.6 0.3 0.18 11.8 0.3 2.0 1 0 0 1 1 1 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. Syntaxin_2 PF14523.6 OAG34010.1 - 2.7 8.4 14.1 0.14 12.5 5.7 3.0 1 1 1 2 2 2 0 Syntaxin-like protein Tyr_Deacylase PF02580.16 OAG34011.1 - 1.3e-51 174.9 0.1 1.7e-51 174.5 0.1 1.1 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase FmdA_AmdA PF03069.15 OAG34012.1 - 2.5e-159 530.1 0.1 5.5e-158 525.7 0.1 2.0 1 1 0 1 1 1 1 Acetamidase/Formamidase family Pro-kuma_activ PF09286.11 OAG34014.1 - 8.7e-37 126.6 0.1 1.3e-36 126.0 0.1 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 OAG34014.1 - 0.002 17.4 0.3 0.0039 16.5 0.3 1.4 1 0 0 1 1 1 1 Subtilase family 2OG-FeII_Oxy PF03171.20 OAG34015.1 - 0.0059 17.1 0.0 0.014 15.8 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Ribosomal_60s PF00428.19 OAG34015.1 - 0.064 13.8 1.7 1.6 9.3 0.4 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein TetR_N PF00440.23 OAG34015.1 - 0.16 11.8 0.1 0.33 10.8 0.1 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family DRMBL PF07522.14 OAG34017.1 - 5.9e-07 29.6 0.0 1.4e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 OAG34017.1 - 2.4e-06 27.2 0.0 6.4e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 OAG34017.1 - 0.001 19.1 0.0 0.0026 17.8 0.0 1.7 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily RMMBL PF07521.12 OAG34017.1 - 0.015 15.2 0.0 0.037 14.0 0.0 1.6 1 0 0 1 1 1 0 Zn-dependent metallo-hydrolase RNA specificity domain NAD_binding_1 PF00175.21 OAG34018.1 - 3e-30 105.1 0.0 5.2e-30 104.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 OAG34018.1 - 3.2e-24 85.2 0.0 7.1e-24 84.0 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 OAG34018.1 - 1e-09 38.7 0.0 1.4e-05 25.3 0.0 2.5 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 OAG34018.1 - 0.15 12.3 0.0 1.6 9.0 0.0 2.4 2 0 0 2 2 2 0 Siderophore-interacting FAD-binding domain MAP17 PF15807.5 OAG34018.1 - 0.2 11.9 0.1 0.34 11.1 0.1 1.2 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 HMG_box PF00505.19 OAG34019.1 - 1.3e-11 44.7 1.9 2.6e-11 43.8 1.9 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 OAG34019.1 - 2.4e-06 28.0 1.7 5.1e-06 27.0 1.7 1.6 1 0 0 1 1 1 1 HMG-box domain CDC45 PF02724.14 OAG34019.1 - 1.4 7.1 11.3 1.8 6.8 11.3 1.1 1 0 0 1 1 1 0 CDC45-like protein DEAD PF00270.29 OAG34020.1 - 1.9e-44 151.5 0.8 3.7e-44 150.6 0.8 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAG34020.1 - 7e-32 110.1 0.4 4.1e-31 107.6 0.1 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG34020.1 - 1.6e-06 28.3 0.0 2.6e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 OAG34020.1 - 0.00027 20.7 0.1 0.00056 19.7 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OAG34020.1 - 0.00075 19.9 0.6 0.006 16.9 0.3 2.2 2 1 0 2 2 2 1 AAA domain CMS1 PF14617.6 OAG34020.1 - 0.0064 15.9 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit AAA_22 PF13401.6 OAG34020.1 - 0.027 14.8 1.0 0.17 12.1 1.0 2.3 1 1 0 1 1 1 0 AAA domain fragilysinNterm PF16376.5 OAG34020.1 - 0.1 12.3 0.0 0.32 10.7 0.0 1.8 1 0 0 1 1 1 0 N-terminal domain of fragilysin IL17R_D_N PF16742.5 OAG34020.1 - 0.1 12.6 0.0 0.28 11.3 0.0 1.7 1 0 0 1 1 1 0 N-terminus of interleukin 17 receptor D Helicase_RecD PF05127.14 OAG34020.1 - 0.12 12.2 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 Helicase Tup_N PF08581.10 OAG34021.1 - 0.024 14.9 4.2 0.069 13.5 0.4 3.1 1 1 1 2 2 2 0 Tup N-terminal Nsp1_C PF05064.13 OAG34021.1 - 0.72 9.7 7.6 1.8 8.4 6.7 2.1 2 1 1 3 3 3 0 Nsp1-like C-terminal region ING PF12998.7 OAG34021.1 - 0.84 10.3 7.7 5.8 7.6 7.7 2.5 1 1 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding Rx_N PF18052.1 OAG34021.1 - 1 9.7 6.4 0.33 11.3 2.5 2.2 2 0 0 2 2 2 0 Rx N-terminal domain DUF1515 PF07439.11 OAG34021.1 - 3.2 7.8 8.4 0.68 10.0 2.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) FAA_hydrolase PF01557.18 OAG34022.1 - 4.1e-50 170.5 0.0 4.9e-50 170.2 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Hexokinase_2 PF03727.16 OAG34024.1 - 6.2e-55 186.2 0.0 1.1e-54 185.4 0.0 1.4 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 OAG34024.1 - 3e-47 161.1 0.0 4.3e-47 160.6 0.0 1.2 1 0 0 1 1 1 1 Hexokinase MTHFR PF02219.17 OAG34026.1 - 1.9e-117 391.7 0.0 2.6e-117 391.2 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Pribosyltran PF00156.27 OAG34027.1 - 3.6e-17 62.3 0.2 5.6e-17 61.7 0.2 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Drf_DAD PF06345.11 OAG34027.1 - 0.018 15.0 0.4 0.59 10.3 0.0 2.8 2 0 0 2 2 2 0 DRF Autoregulatory Domain PRTase_2 PF15609.6 OAG34027.1 - 0.078 12.5 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase dCMP_cyt_deam_1 PF00383.23 OAG34028.1 - 0.0001 22.1 0.0 0.00024 20.9 0.0 1.6 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 OAG34028.1 - 0.00044 20.0 0.0 0.00094 18.9 0.0 1.6 1 0 0 1 1 1 1 MafB19-like deaminase Flagellin_C PF00700.21 OAG34029.1 - 0.0096 16.3 2.9 1.1 9.6 0.2 2.6 2 0 0 2 2 2 2 Bacterial flagellin C-terminal helical region AAA_13 PF13166.6 OAG34029.1 - 0.11 11.1 2.4 0.16 10.6 2.4 1.1 1 0 0 1 1 1 0 AAA domain Flg_hook PF02120.16 OAG34029.1 - 0.22 11.4 4.1 0.32 10.9 0.2 2.5 1 1 1 2 2 2 0 Flagellar hook-length control protein FliK CENP-F_leu_zip PF10473.9 OAG34029.1 - 0.73 9.9 8.9 0.47 10.5 0.8 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Sec2p PF06428.11 OAG34029.1 - 4.3 7.4 9.3 6.9 6.7 4.3 2.6 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p NOT2_3_5 PF04153.18 OAG34030.1 - 4.6e-25 88.2 0.3 4.6e-25 88.2 0.3 1.7 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family DUF676 PF05057.14 OAG34031.1 - 2.2e-06 27.4 0.0 3.6e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 OAG34031.1 - 0.01 15.6 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 OAG34031.1 - 0.091 13.3 0.0 0.13 12.8 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family 3Beta_HSD PF01073.19 OAG34034.1 - 1.7e-56 191.3 0.0 2.3e-56 190.8 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 OAG34034.1 - 5.9e-36 124.1 0.0 7.9e-36 123.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 OAG34034.1 - 1.8e-18 66.6 0.0 4.1e-18 65.5 0.0 1.6 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.17 OAG34034.1 - 9.7e-18 64.3 0.0 2e-17 63.2 0.0 1.5 1 1 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 OAG34034.1 - 8e-17 61.6 0.0 5.3e-15 55.7 0.0 2.1 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase KR PF08659.10 OAG34034.1 - 1.3e-11 44.7 0.0 2.1e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OAG34034.1 - 5.5e-09 35.6 0.0 3.9e-08 32.8 0.0 2.0 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 OAG34034.1 - 7.9e-06 25.9 0.0 1.4e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 OAG34034.1 - 0.0013 19.0 0.0 0.0031 17.8 0.0 1.8 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain adh_short PF00106.25 OAG34034.1 - 0.0022 17.5 0.0 0.0037 16.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase TrkA_N PF02254.18 OAG34034.1 - 0.11 12.7 0.1 0.67 10.2 0.0 2.4 2 1 0 2 2 2 0 TrkA-N domain Spt5-NGN PF03439.13 OAG34035.1 - 1.8e-24 85.4 0.0 3.9e-24 84.3 0.0 1.6 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.8 OAG34035.1 - 2e-17 64.0 10.5 2e-17 64.0 10.5 4.4 3 1 0 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal CTD PF12815.7 OAG34035.1 - 4.5e-15 56.0 37.4 6.9e-10 39.4 19.7 4.6 2 1 2 4 4 4 2 Spt5 C-terminal nonapeptide repeat binding Spt4 KOW PF00467.29 OAG34035.1 - 5.9e-07 29.2 12.9 0.018 15.0 1.5 5.3 5 0 0 5 5 5 2 KOW motif Arabino_trans_N PF17689.1 OAG34035.1 - 0.083 13.0 0.4 1.3 9.2 0.1 2.4 2 0 0 2 2 2 0 Arabinosyltransferase concanavalin like domain Aldedh PF00171.22 OAG34036.1 - 8.7e-183 608.0 0.1 9.9e-183 607.9 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family EVE PF01878.18 OAG34037.1 - 1.7e-50 170.8 0.0 3.3e-50 169.9 0.0 1.5 1 0 0 1 1 1 1 EVE domain Ndc1_Nup PF09531.10 OAG34037.1 - 8.7 4.9 11.1 11 4.6 11.1 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup bZIP_2 PF07716.15 OAG34038.1 - 0.00037 20.5 5.7 0.00073 19.6 5.7 1.4 1 0 0 1 1 1 1 Basic region leucine zipper HipA_C PF07804.12 OAG34039.1 - 0.063 13.0 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 HipA-like C-terminal domain DUF2780 PF11075.8 OAG34039.1 - 0.14 12.3 0.1 0.22 11.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function VcgC/VcgE (DUF2780) Myb_DNA-binding PF00249.31 OAG34045.1 - 4.9e-34 116.3 12.3 3.5e-11 43.1 0.4 3.8 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OAG34045.1 - 9.9e-15 54.5 12.7 0.00011 22.4 2.2 4.3 3 1 1 4 4 4 3 Myb-like DNA-binding domain HTH_32 PF13565.6 OAG34045.1 - 2.9e-06 27.8 7.0 0.11 13.1 0.2 3.5 1 1 2 3 3 3 3 Homeodomain-like domain SLIDE PF09111.10 OAG34045.1 - 3.4e-06 27.1 0.2 0.53 10.3 0.0 3.2 1 1 1 3 3 3 2 SLIDE HTH_23 PF13384.6 OAG34045.1 - 0.00054 19.7 0.1 4.9 7.1 0.0 3.6 3 0 0 3 3 3 1 Homeodomain-like domain DUF433 PF04255.14 OAG34045.1 - 0.004 17.0 0.0 6.8 6.6 0.0 3.3 3 0 0 3 3 3 1 Protein of unknown function (DUF433) Myb_DNA-bind_4 PF13837.6 OAG34045.1 - 8.2 6.9 10.7 11 6.5 0.9 4.5 4 2 0 4 4 4 0 Myb/SANT-like DNA-binding domain DUF4805 PF16063.5 OAG34046.1 - 0.0029 17.0 2.5 0.0029 17.0 2.5 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4805) LAP1C PF05609.12 OAG34047.1 - 0.07 12.2 10.7 0.089 11.9 10.7 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF3781 PF12636.7 OAG34048.1 - 0.2 11.5 1.1 1.6 8.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3781) Septin PF00735.18 OAG34049.1 - 8.5e-36 123.7 0.0 1.3e-12 47.6 0.0 3.1 3 0 0 3 3 3 3 Septin MMR_HSR1 PF01926.23 OAG34049.1 - 0.0019 18.2 0.0 0.0044 17.1 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 OAG34049.1 - 0.026 13.9 0.0 0.045 13.1 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family CDC45 PF02724.14 OAG34049.1 - 0.098 10.9 0.6 0.14 10.4 0.6 1.2 1 0 0 1 1 1 0 CDC45-like protein AAA_14 PF13173.6 OAG34049.1 - 0.14 12.2 0.0 0.33 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain Ras PF00071.22 OAG34049.1 - 0.17 11.4 0.1 2.3 7.8 0.1 2.3 1 1 0 1 1 1 0 Ras family DNA_pol_phi PF04931.13 OAG34049.1 - 8 4.4 8.0 11 3.9 8.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi BLOC1S3 PF15753.5 OAG34050.1 - 0.098 12.8 1.0 0.2 11.8 1.0 1.4 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 DOPA_dioxygen PF08883.11 OAG34051.1 - 3.2e-41 139.8 0.0 3.9e-41 139.5 0.0 1.1 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family ELP6 PF09807.9 OAG34052.1 - 1.8e-06 27.6 0.0 3.8e-05 23.2 0.0 2.0 2 0 0 2 2 2 2 Elongation complex protein 6 DUF835 PF05763.12 OAG34052.1 - 0.057 13.2 0.0 0.61 9.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF835) Glyco_hydro_16 PF00722.21 OAG34053.1 - 3.4e-37 127.6 0.6 6.9e-37 126.6 0.6 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 LysM PF01476.20 OAG34053.1 - 6.2e-05 23.0 0.1 0.00013 22.0 0.1 1.6 1 0 0 1 1 1 1 LysM domain PAN_1 PF00024.26 OAG34053.1 - 0.061 13.3 1.1 0.16 11.9 0.3 2.2 2 0 0 2 2 2 0 PAN domain NFACT-R_1 PF05670.13 OAG34054.1 - 9e-32 110.0 0.0 2.1e-31 108.8 0.0 1.6 1 1 0 1 1 1 1 NFACT protein RNA binding domain PVL_ORF50 PF07768.11 OAG34054.1 - 0.041 14.2 5.7 0.062 13.6 5.7 1.3 1 0 0 1 1 1 0 PVL ORF-50-like family Atrophin-1 PF03154.15 OAG34054.1 - 6.2 5.0 12.9 7.9 4.6 12.9 1.1 1 0 0 1 1 1 0 Atrophin-1 family Thiolase_N PF00108.23 OAG34056.1 - 1e-21 77.5 0.0 6.6e-20 71.6 0.0 2.4 2 1 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 OAG34056.1 - 3.7e-13 49.2 0.6 7.9e-13 48.1 0.1 1.9 2 0 0 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III PF08545.10 OAG34056.1 - 5.8e-08 32.5 0.2 1.2e-05 25.1 0.1 2.6 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.26 OAG34056.1 - 2.1e-07 30.8 0.6 1.7e-05 24.5 0.2 2.6 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 OAG34056.1 - 0.0016 18.4 0.1 0.056 13.5 0.0 2.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain DFP PF04127.15 OAG34056.1 - 0.031 14.1 0.2 0.11 12.3 0.0 1.8 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein SmaI PF17411.2 OAG34056.1 - 0.098 11.8 0.0 0.19 10.9 0.0 1.4 1 0 0 1 1 1 0 Type II site-specific deoxyribonuclease Mito_carr PF00153.27 OAG34057.1 - 1.5e-40 137.0 7.2 4.5e-15 55.3 0.3 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF2620 PF10941.8 OAG34057.1 - 0.26 11.4 1.0 8.9 6.5 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function DUF2620 Oxidored_FMN PF00724.20 OAG34058.1 - 2.3e-37 129.1 0.0 2.9e-37 128.7 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Gas_vesicle_C PF01304.17 OAG34058.1 - 0.2 11.7 2.7 3.4 7.7 0.8 2.8 2 0 0 2 2 2 0 Gas vesicles protein GVPc repeated domain DUF202 PF02656.15 OAG34059.1 - 1.5e-15 57.3 3.1 9.2e-15 54.8 1.8 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Trp_oprn_chp PF09534.10 OAG34059.1 - 0.00067 19.5 0.3 0.0012 18.7 0.3 1.4 1 1 0 1 1 1 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Sugar_tr PF00083.24 OAG34062.1 - 2.9e-77 260.4 20.8 3.4e-77 260.2 20.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG34062.1 - 5.7e-28 97.8 22.7 5.7e-28 97.8 22.7 2.0 1 1 0 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.25 OAG34063.1 - 2e-10 40.5 0.0 2.4e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Lin-8 PF03353.15 OAG34064.1 - 0.0051 16.4 2.1 0.009 15.6 2.1 1.3 1 0 0 1 1 1 1 Ras-mediated vulval-induction antagonist Aldo_ket_red PF00248.21 OAG34065.1 - 1.1e-10 41.2 0.0 1.6e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Pkinase PF00069.25 OAG34066.1 - 1.9e-06 27.5 0.0 7.6e-06 25.5 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 OAG34066.1 - 3.3e-06 26.6 0.0 0.0059 16.0 0.0 3.1 2 1 1 3 3 3 2 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OAG34066.1 - 0.00035 20.6 0.2 0.014 15.4 0.1 2.7 2 1 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OAG34066.1 - 0.089 11.5 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Choline_kinase PF01633.20 OAG34066.1 - 0.09 12.4 0.0 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.22 OAG34066.1 - 0.14 11.8 0.0 0.34 10.5 0.0 1.6 1 0 0 1 1 1 0 RIO1 family EIF_2_alpha PF07541.12 OAG34068.1 - 1.4e-37 128.3 0.0 2.7e-37 127.4 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 OAG34068.1 - 1.4e-13 50.9 0.6 2.7e-13 50.0 0.6 1.5 1 0 0 1 1 1 1 S1 RNA binding domain Ion_trans PF00520.31 OAG34070.1 - 1.9e-07 30.6 19.7 1e-06 28.2 19.7 2.0 1 1 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 OAG34070.1 - 0.0036 16.0 18.3 0.034 12.8 18.3 2.1 1 1 0 1 1 1 1 Polycystin cation channel U79_P34 PF03064.16 OAG34071.1 - 9 5.6 11.7 20 4.5 11.7 1.5 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF501 PF04417.12 OAG34073.1 - 5.1 6.9 5.7 1.6 8.5 1.0 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF501) Scs3p PF10261.9 OAG34075.1 - 1.4e-66 224.5 4.5 2.1e-66 224.0 4.5 1.3 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM BCS1_N PF08740.11 OAG34076.1 - 8.6e-29 100.9 0.0 2.1e-28 99.6 0.0 1.6 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 OAG34076.1 - 7e-16 58.9 0.0 7.6e-07 29.6 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 OAG34076.1 - 0.00031 20.6 0.5 0.41 10.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.12 OAG34076.1 - 0.00069 19.4 0.0 0.0013 18.5 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 OAG34076.1 - 0.00085 19.7 0.1 0.012 16.0 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 OAG34076.1 - 0.0086 16.1 0.0 0.031 14.3 0.0 2.0 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 OAG34076.1 - 0.041 13.6 0.0 0.077 12.7 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_7 PF12775.7 OAG34076.1 - 0.045 13.3 0.0 0.086 12.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region ParA PF10609.9 OAG34076.1 - 0.09 12.2 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase DNA_pol3_delta2 PF13177.6 OAG34076.1 - 0.16 11.7 0.0 1.5 8.6 0.0 2.3 2 0 0 2 2 2 0 DNA polymerase III, delta subunit AAA_18 PF13238.6 OAG34076.1 - 0.19 12.3 0.0 0.19 12.3 0.0 3.0 3 0 0 3 3 2 0 AAA domain AAA_33 PF13671.6 OAG34076.1 - 0.23 11.6 0.0 0.23 11.6 0.0 2.9 3 0 0 3 3 3 0 AAA domain Med2 PF11214.8 OAG34076.1 - 8.4 6.6 7.8 22 5.3 7.8 1.7 1 0 0 1 1 1 0 Mediator complex subunit 2 Steroid_dh PF02544.16 OAG34077.1 - 3.8e-05 23.7 8.8 0.00012 22.1 1.3 2.8 3 1 0 3 3 3 2 3-oxo-5-alpha-steroid 4-dehydrogenase Ribosomal_L7Ae PF01248.26 OAG34078.1 - 2.7e-25 87.9 1.1 5.6e-25 86.9 1.1 1.6 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Ank_2 PF12796.7 OAG34078.1 - 1.2e-24 86.7 0.0 1.9e-09 38.0 0.0 3.6 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAG34078.1 - 5.3e-22 77.9 0.0 4e-09 36.8 0.0 3.8 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 OAG34078.1 - 2.1e-21 75.7 0.4 8e-09 35.6 0.0 6.0 3 2 3 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG34078.1 - 3.4e-15 54.6 0.5 0.0003 21.0 0.0 5.8 6 0 0 6 6 6 3 Ankyrin repeat Ank PF00023.30 OAG34078.1 - 2e-13 50.1 0.1 0.0074 16.7 0.0 5.1 5 0 0 5 5 5 3 Ankyrin repeat SLC35F PF06027.12 OAG34079.1 - 6.8e-92 308.2 25.8 1.6e-73 247.9 17.3 2.0 1 1 1 2 2 2 2 Solute carrier family 35 CRT-like PF08627.10 OAG34079.1 - 5.7e-10 38.7 3.3 7.7e-10 38.2 1.3 2.0 1 1 1 2 2 2 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 OAG34079.1 - 0.2 11.8 32.7 0.041 14.1 12.7 3.0 2 1 1 3 3 3 0 EamA-like transporter family HCV_env PF01539.17 OAG34079.1 - 1.9 8.1 5.6 0.31 10.7 1.0 1.9 2 0 0 2 2 2 0 Hepatitis C virus envelope glycoprotein E1 Acyl_transf_3 PF01757.22 OAG34080.1 - 8.7e-34 117.1 21.9 1.3e-33 116.5 21.9 1.3 1 0 0 1 1 1 1 Acyltransferase family Epimerase PF01370.21 OAG34081.1 - 8.6e-11 41.8 0.0 9.7e-10 38.3 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 OAG34081.1 - 4.7e-09 35.8 0.0 7.9e-08 31.8 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein Sacchrp_dh_NADP PF03435.18 OAG34081.1 - 5.3e-07 30.0 0.0 9.9e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 OAG34081.1 - 5.6e-06 26.4 0.4 1e-05 25.6 0.0 1.6 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 OAG34081.1 - 0.0027 17.3 0.0 0.0041 16.7 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family DapB_N PF01113.20 OAG34081.1 - 0.025 14.7 0.0 0.045 13.9 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Polysacc_synt_2 PF02719.15 OAG34081.1 - 0.028 13.5 0.0 0.08 12.1 0.0 1.7 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.24 OAG34081.1 - 0.03 14.8 0.0 0.062 13.7 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.10 OAG34081.1 - 0.068 13.1 0.0 0.12 12.3 0.0 1.5 1 1 0 1 1 1 0 KR domain GDP_Man_Dehyd PF16363.5 OAG34081.1 - 0.1 11.9 0.0 0.29 10.5 0.0 1.7 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 OAG34081.1 - 0.11 11.4 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 OAG34081.1 - 0.12 11.8 0.2 0.52 9.7 0.2 2.0 1 1 0 1 1 1 0 short chain dehydrogenase Ctr PF04145.15 OAG34082.1 - 4.3e-33 115.0 0.1 9.1e-33 114.0 0.1 1.5 1 0 0 1 1 1 1 Ctr copper transporter family Oxidored_q3 PF00499.20 OAG34082.1 - 0.013 15.2 0.3 0.29 10.9 0.2 2.6 3 0 0 3 3 3 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 Acyl-CoA_ox_N PF14749.6 OAG34083.1 - 8.2e-20 71.6 0.2 2.1e-19 70.3 0.1 1.8 2 0 0 2 2 2 1 Acyl-coenzyme A oxidase N-terminal ACOX PF01756.19 OAG34083.1 - 4.7e-10 39.3 0.0 8.6e-10 38.5 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.19 OAG34083.1 - 5.2e-09 36.2 0.0 1.3e-08 34.9 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 OAG34083.1 - 4.4e-05 23.7 0.2 8.4e-05 22.8 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HET PF06985.11 OAG34084.1 - 8.5e-32 110.5 0.6 1.3e-31 109.9 0.6 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) FAD_binding_2 PF00890.24 OAG34087.1 - 1e-88 298.2 0.0 1.2e-88 298.0 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAG34087.1 - 4.9e-13 49.4 3.3 1e-11 45.1 3.2 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 OAG34087.1 - 2e-11 43.9 2.8 4.5e-09 36.2 1.4 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.17 OAG34087.1 - 2.3e-09 36.8 0.3 1.6e-08 34.1 0.2 2.3 3 0 0 3 3 3 1 Thi4 family HI0933_like PF03486.14 OAG34087.1 - 1.7e-07 30.3 1.3 5.3e-07 28.7 0.5 1.9 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.6 OAG34087.1 - 2e-07 31.1 0.6 4.7e-07 29.9 0.6 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAG34087.1 - 1.3e-05 24.7 0.9 0.00014 21.2 0.0 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 OAG34087.1 - 0.00019 20.8 0.5 0.00069 19.0 0.1 1.9 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.22 OAG34087.1 - 0.0053 15.9 3.3 0.01 15.0 1.2 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 OAG34087.1 - 0.012 14.9 0.2 0.023 14.0 0.2 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAG34087.1 - 0.026 14.5 0.1 0.067 13.2 0.0 1.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 OAG34087.1 - 0.027 13.8 0.1 0.046 13.0 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GDI PF00996.18 OAG34087.1 - 0.033 12.7 0.1 0.049 12.2 0.1 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor Pyr_redox PF00070.27 OAG34087.1 - 0.062 13.9 0.8 0.23 12.0 0.3 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OAG34087.1 - 0.14 11.2 0.0 0.22 10.5 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein 3HCDH_N PF02737.18 OAG34087.1 - 0.29 11.0 0.5 0.46 10.4 0.5 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain adh_short PF00106.25 OAG34088.1 - 6.3e-38 130.2 4.1 1e-37 129.5 3.4 1.6 1 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG34088.1 - 3e-30 105.5 1.6 4.7e-30 104.9 1.6 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG34088.1 - 4e-08 33.4 1.2 6.8e-08 32.6 1.2 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG34088.1 - 0.039 13.4 1.0 0.13 11.7 1.0 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family p450 PF00067.22 OAG34089.1 - 5.8e-67 226.4 0.0 8.4e-67 225.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Sugar_tr PF00083.24 OAG34090.1 - 1.1e-63 215.7 27.7 1.6e-41 142.7 10.9 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 OAG34090.1 - 1.4e-16 60.3 36.1 1.2e-08 34.3 9.4 3.1 1 1 2 3 3 3 3 Major Facilitator Superfamily ABM PF03992.16 OAG34091.1 - 2.5e-05 24.3 0.1 0.28 11.3 0.0 2.5 2 1 1 3 3 3 2 Antibiotic biosynthesis monooxygenase DUF1330 PF07045.11 OAG34091.1 - 0.026 14.9 0.0 0.063 13.6 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1330) DNA_pol_phi PF04931.13 OAG34092.1 - 8.5 4.3 7.9 12 3.9 7.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi Ribonuclease_3 PF00636.26 OAG34094.1 - 5.7e-40 136.2 0.0 9.8e-22 77.6 0.0 2.9 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 OAG34094.1 - 1.2e-29 103.1 0.0 3.2e-16 59.6 0.0 3.6 2 1 0 3 3 3 3 Ribonuclease-III-like Dicer_dimer PF03368.14 OAG34094.1 - 8.1e-24 83.6 0.4 5.7e-23 80.9 0.1 2.5 2 0 0 2 2 2 1 Dicer dimerisation domain Helicase_C PF00271.31 OAG34094.1 - 1.3e-18 67.4 0.1 3.9e-18 65.8 0.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 OAG34094.1 - 5.2e-05 23.1 0.0 0.00011 22.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 OAG34094.1 - 0.0024 17.9 0.0 0.0049 16.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Piwi PF02171.17 OAG34095.1 - 1.3e-74 251.2 0.0 2.1e-74 250.5 0.0 1.3 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 OAG34095.1 - 4.7e-17 62.9 0.0 1.6e-16 61.2 0.0 2.0 2 0 0 2 2 2 1 N-terminal domain of argonaute ArgoL1 PF08699.10 OAG34095.1 - 7.6e-10 38.3 0.0 1.8e-09 37.1 0.0 1.7 1 0 0 1 1 1 1 Argonaute linker 1 domain PAZ PF02170.22 OAG34095.1 - 6.8e-09 35.7 0.0 1.7e-08 34.4 0.0 1.6 2 0 0 2 2 2 1 PAZ domain ArgoL2 PF16488.5 OAG34095.1 - 3.2e-07 30.6 0.0 7.5e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 Argonaute linker 2 domain Glyco_trans_1_2 PF13524.6 OAG34095.1 - 0.026 14.9 0.0 0.51 10.8 0.0 2.5 2 0 0 2 2 2 0 Glycosyl transferases group 1 ArgoMid PF16487.5 OAG34095.1 - 0.033 14.5 0.0 0.086 13.1 0.0 1.7 1 0 0 1 1 1 0 Mid domain of argonaute AAA PF00004.29 OAG34096.1 - 3.2e-11 43.8 0.0 6.5e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OAG34096.1 - 0.00071 19.9 0.0 0.015 15.5 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 OAG34097.1 - 8.5e-21 74.9 0.2 1.1e-18 67.9 0.1 2.6 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 OAG34097.1 - 6.6e-18 65.4 0.0 8e-06 26.3 0.0 3.7 3 0 0 3 3 3 3 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 OAG34097.1 - 3.7e-11 43.1 0.0 0.0036 17.0 0.0 3.7 3 0 0 3 3 3 3 AAA domain AAA_19 PF13245.6 OAG34097.1 - 3.1e-10 40.6 0.0 2.4e-06 27.9 0.0 3.3 2 2 0 2 2 2 2 AAA domain AAA_lid_6 PF17866.1 OAG34097.1 - 9.1e-08 32.2 0.2 0.018 15.2 0.0 2.7 2 0 0 2 2 2 2 AAA lid domain AAA_5 PF07728.14 OAG34097.1 - 5.6e-05 23.2 0.2 0.27 11.2 0.0 3.5 4 0 0 4 4 4 2 AAA domain (dynein-related subfamily) AAA_12 PF13087.6 OAG34097.1 - 9.5e-05 22.1 0.0 0.00016 21.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 OAG34097.1 - 0.00012 22.4 0.5 7.1 6.9 0.0 4.9 4 2 1 5 5 5 2 AAA domain DUF2075 PF09848.9 OAG34097.1 - 0.00083 18.7 0.0 0.046 13.0 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.22 OAG34097.1 - 0.0034 17.8 0.0 2.5 8.5 0.0 2.7 2 0 0 2 2 2 1 RNA helicase IstB_IS21 PF01695.17 OAG34097.1 - 0.008 15.9 0.0 4.2 7.1 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_16 PF13191.6 OAG34097.1 - 0.0098 16.3 0.2 6.3 7.2 0.0 3.2 3 0 0 3 3 3 1 AAA ATPase domain PhoH PF02562.16 OAG34097.1 - 0.022 14.2 0.0 1.3 8.4 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein Torsin PF06309.11 OAG34097.1 - 0.041 14.0 0.0 14 5.8 0.0 2.5 2 0 0 2 2 2 0 Torsin AAA_18 PF13238.6 OAG34097.1 - 0.044 14.3 0.4 29 5.2 0.1 3.5 3 0 0 3 3 3 0 AAA domain ATPase PF06745.13 OAG34097.1 - 0.066 12.5 0.1 5.5 6.3 0.0 2.4 2 0 0 2 2 2 0 KaiC Mg_chelatase PF01078.21 OAG34097.1 - 0.077 12.4 0.0 15 4.9 0.0 2.8 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI TniB PF05621.11 OAG34097.1 - 0.11 11.9 0.0 0.95 8.8 0.0 2.7 3 0 0 3 3 3 0 Bacterial TniB protein RHSP PF07999.11 OAG34097.1 - 0.17 10.6 0.0 0.31 9.8 0.0 1.3 1 0 0 1 1 1 0 Retrotransposon hot spot protein Ribonucleas_3_3 PF14622.6 OAG34098.1 - 5.2e-07 29.9 0.0 1.1e-06 28.8 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 OAG34098.1 - 3.7e-05 24.3 0.4 0.00013 22.5 0.0 2.2 3 0 0 3 3 3 1 Ribonuclease III domain DUF3449 PF11931.8 OAG34099.1 - 0.00038 20.3 1.8 0.015 15.1 0.1 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF3449) zf-UBP PF02148.19 OAG34099.1 - 0.024 15.0 2.1 5.3 7.5 0.2 2.4 1 1 1 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein DUF4451 PF14616.6 OAG34099.1 - 0.063 13.5 0.2 7.7 6.7 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4451) HNH PF01844.23 OAG34100.1 - 0.12 12.6 2.9 0.4 10.9 2.9 1.9 1 1 0 1 1 1 0 HNH endonuclease SapB_1 PF05184.15 OAG34100.1 - 3.4 7.8 4.5 32 4.7 0.1 3.2 3 0 0 3 3 3 0 Saposin-like type B, region 1 Zn_clus PF00172.18 OAG34101.1 - 3.4e-08 33.5 9.9 5.9e-08 32.7 9.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAG34101.1 - 0.001 18.2 0.0 0.0063 15.6 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain EI24 PF07264.11 OAG34102.1 - 1.2e-13 51.7 16.0 1.8e-13 51.2 16.0 1.2 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) HAD_2 PF13419.6 OAG34103.1 - 4.4e-13 49.7 0.0 6.2e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OAG34103.1 - 6e-08 33.2 0.0 2.3e-07 31.3 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OAG34103.1 - 0.00049 20.1 0.0 0.00089 19.3 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 OAG34103.1 - 0.0017 18.4 0.1 0.0088 16.1 0.1 2.2 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Tricorn_C1 PF14684.6 OAG34103.1 - 0.12 12.5 0.1 0.24 11.5 0.1 1.5 1 0 0 1 1 1 0 Tricorn protease C1 domain TRI12 PF06609.13 OAG34104.1 - 1.4e-25 89.7 25.1 1.9e-25 89.3 25.1 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG34104.1 - 1e-24 87.1 51.0 1e-24 87.1 51.0 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.6 OAG34104.1 - 0.0025 16.4 1.4 0.0025 16.4 1.4 3.7 2 1 2 4 4 4 1 MFS/sugar transport protein p450 PF00067.22 OAG34105.1 - 1.9e-64 218.2 0.0 2.5e-64 217.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.25 OAG34106.1 - 4.3e-28 98.1 0.0 6.4e-21 74.7 0.0 2.6 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAG34106.1 - 7.9e-20 71.4 0.0 1.7e-13 50.7 0.0 2.3 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase TrkA_N PF02254.18 OAG34106.1 - 0.003 17.8 0.1 0.012 15.9 0.1 1.9 2 0 0 2 2 2 1 TrkA-N domain KR PF08659.10 OAG34106.1 - 0.028 14.3 0.2 0.16 11.9 0.1 2.2 3 0 0 3 3 3 0 KR domain NAD_binding_2 PF03446.15 OAG34106.1 - 0.078 13.1 0.1 0.13 12.5 0.1 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Epimerase PF01370.21 OAG34106.1 - 0.18 11.3 0.2 0.33 10.4 0.2 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 OAG34106.1 - 0.33 10.8 2.2 0.3 10.9 0.2 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF3425 PF11905.8 OAG34107.1 - 1.4e-14 54.2 0.5 3e-14 53.1 0.5 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) Fungal_trans PF04082.18 OAG34108.1 - 5.1e-15 55.2 0.6 2e-07 30.3 0.1 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain MFS_1 PF07690.16 OAG34110.1 - 5.1e-36 124.3 34.2 5.1e-36 124.3 34.2 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Protocadherin PF08374.11 OAG34110.1 - 0.098 12.6 0.1 4.7 7.1 0.1 2.2 2 0 0 2 2 2 0 Protocadherin EphA2_TM PF14575.6 OAG34110.1 - 0.43 11.5 2.4 3 8.8 1.7 2.4 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Trp_oprn_chp PF09534.10 OAG34110.1 - 0.94 9.2 4.0 1.8 8.4 1.8 2.3 2 1 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) adh_short PF00106.25 OAG34111.1 - 1.5e-42 145.2 1.3 1.5e-42 145.2 1.3 1.4 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG34111.1 - 1.9e-32 112.7 3.3 2.7e-32 112.2 3.3 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG34111.1 - 8.4e-07 29.1 2.3 1.8e-05 24.7 2.3 2.2 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG34111.1 - 0.0011 18.5 1.0 0.0064 16.0 0.1 2.3 2 1 1 3 3 3 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAG34111.1 - 0.0022 17.4 0.0 1.5 8.1 0.0 2.1 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase ADH_zinc_N PF00107.26 OAG34111.1 - 0.033 14.1 2.4 0.079 12.9 0.2 2.3 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Rhomboid_SP PF12595.8 OAG34111.1 - 0.11 11.9 0.0 0.26 10.6 0.0 1.5 2 0 0 2 2 2 0 Rhomboid serine protease HpcH_HpaI PF03328.14 OAG34112.1 - 4.8e-30 104.3 0.0 5.9e-30 104.1 0.0 1.0 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family DEC-1_N PF04625.13 OAG34113.1 - 0.41 9.6 2.9 0.69 8.9 2.9 1.3 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region CoA_transf_3 PF02515.17 OAG34114.1 - 1.6e-40 139.4 0.0 3.6e-38 131.7 0.0 2.1 2 0 0 2 2 2 2 CoA-transferase family III SGL PF08450.12 OAG34115.1 - 0.017 14.7 0.0 0.029 14.0 0.0 1.3 1 0 0 1 1 1 0 SMP-30/Gluconolactonase/LRE-like region Glyco_hydro_42C PF08533.10 OAG34115.1 - 0.02 14.6 0.0 0.055 13.2 0.0 1.7 1 0 0 1 1 1 0 Beta-galactosidase C-terminal domain Arylesterase PF01731.20 OAG34115.1 - 0.047 13.9 0.0 0.19 12.0 0.0 2.1 1 1 0 1 1 1 0 Arylesterase Glyco_hydro_43 PF04616.14 OAG34116.1 - 2.3e-33 115.7 0.0 3e-33 115.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 DUF5348 PF17295.2 OAG34116.1 - 0.14 12.1 0.1 1.3 9.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5348) Sfi1 PF08457.10 OAG34117.1 - 6.8e-40 137.2 59.8 7.3e-21 74.3 25.2 3.3 1 1 2 3 3 3 3 Sfi1 spindle body protein CaM_bdg_C0 PF10562.9 OAG34117.1 - 0.42 10.7 16.0 0.22 11.6 2.1 5.2 5 0 0 5 5 5 0 Calmodulin-binding domain C0 of NMDA receptor NR1 subunit p450 PF00067.22 OAG34118.1 - 4.7e-68 230.0 0.0 5.4e-68 229.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 OAG34120.1 - 4e-34 118.1 22.8 6.1e-34 117.5 22.8 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily AzlD PF05437.12 OAG34120.1 - 0.044 14.0 4.1 0.56 10.4 0.3 2.8 2 0 0 2 2 2 0 Branched-chain amino acid transport protein (AzlD) DUF4064 PF13273.6 OAG34120.1 - 0.44 10.8 8.6 0.51 10.6 0.8 3.7 2 2 1 3 3 3 0 Protein of unknown function (DUF4064) Iso_dh PF00180.20 OAG34121.1 - 8.8e-96 321.1 0.0 1e-95 320.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Aconitase PF00330.20 OAG34122.1 - 4.2e-145 484.3 0.0 5e-145 484.0 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 OAG34122.1 - 1.5e-32 112.7 0.0 2.8e-32 111.8 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain Aconitase_2_N PF06434.13 OAG34122.1 - 0.014 15.0 0.0 0.31 10.6 0.0 2.5 1 1 0 1 1 1 0 Aconitate hydratase 2 N-terminus Lactamase_B PF00753.27 OAG34123.1 - 2.1e-05 24.6 0.4 4.9e-05 23.4 0.3 1.7 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OAG34123.1 - 0.0023 17.5 0.2 0.028 13.9 0.0 2.4 2 0 0 2 2 2 1 Beta-lactamase superfamily domain MerB PF03243.15 OAG34123.1 - 0.011 15.9 0.0 0.019 15.1 0.0 1.4 1 0 0 1 1 1 0 Alkylmercury lyase GTP1_OBG PF01018.22 OAG34124.1 - 4.3e-39 133.6 1.4 1.7e-28 99.2 3.2 2.2 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.23 OAG34124.1 - 2.7e-21 75.8 0.0 4.8e-21 75.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OAG34124.1 - 9e-05 22.1 0.1 0.00029 20.4 0.0 1.8 2 1 0 2 2 2 1 Ferrous iron transport protein B MeaB PF03308.16 OAG34124.1 - 0.015 14.3 2.4 2.2 7.2 0.1 2.9 2 1 1 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 OAG34124.1 - 0.11 13.1 0.0 0.26 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain NST1 PF13945.6 OAG34125.1 - 1.7e-60 204.4 3.9 1.7e-60 204.4 3.9 4.7 3 2 2 5 5 5 1 Salt tolerance down-regulator Ras PF00071.22 OAG34126.1 - 4.9e-50 169.3 0.0 5.7e-50 169.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAG34126.1 - 3.9e-22 78.7 0.0 5.8e-22 78.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAG34126.1 - 2.2e-07 30.5 0.0 3.3e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 OAG34126.1 - 0.0015 18.0 0.0 0.002 17.6 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 OAG34126.1 - 0.0094 15.3 0.0 0.012 14.9 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 OAG34126.1 - 0.043 13.6 0.0 3 7.6 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ADH_zinc_N PF00107.26 OAG34126.1 - 0.055 13.4 0.0 7.5 6.6 0.0 2.3 2 0 0 2 2 2 0 Zinc-binding dehydrogenase MMR_HSR1 PF01926.23 OAG34126.1 - 0.091 12.9 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_21 PF13304.6 OAG34126.1 - 0.21 11.4 0.0 0.25 11.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system MRP-L28 PF09812.9 OAG34127.1 - 2.1e-06 28.0 0.0 3.2e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 RINGv PF12906.7 OAG34127.1 - 8.1e-06 25.9 7.6 1.5e-05 25.0 7.6 1.5 1 0 0 1 1 1 1 RING-variant domain FANCL_C PF11793.8 OAG34127.1 - 0.00016 21.8 4.1 0.00033 20.8 4.1 1.4 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING_2 PF13639.6 OAG34127.1 - 2.5 8.5 12.4 0.14 12.5 7.0 1.8 2 0 0 2 2 2 0 Ring finger domain Fungal_trans_2 PF11951.8 OAG34128.1 - 0.041 12.7 0.0 0.068 12.0 0.0 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain GalKase_gal_bdg PF10509.9 OAG34129.1 - 2e-19 68.9 0.0 4.8e-19 67.6 0.0 1.6 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.26 OAG34129.1 - 3.5e-14 52.8 3.0 8.3e-14 51.6 3.0 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 OAG34129.1 - 5e-14 52.4 0.0 2e-13 50.5 0.0 2.0 1 0 0 1 1 1 1 GHMP kinases C terminal Phage_antiter_Q PF06323.11 OAG34129.1 - 0.032 13.8 0.0 0.052 13.1 0.0 1.2 1 0 0 1 1 1 0 Phage antitermination protein Q HTH_23 PF13384.6 OAG34129.1 - 0.056 13.3 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain HTH_7 PF02796.15 OAG34129.1 - 0.065 13.3 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase Sigma70_r4_2 PF08281.12 OAG34129.1 - 0.17 11.6 0.1 0.33 10.7 0.1 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 DUF2316 PF10078.9 OAG34129.1 - 0.18 12.0 0.0 9.2 6.6 0.0 2.3 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2316) AMP-binding PF00501.28 OAG34130.1 - 5.2e-100 335.0 0.0 6.3e-100 334.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG34130.1 - 2.7e-12 47.5 0.4 9.6e-12 45.7 0.4 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain LEM PF03020.15 OAG34131.1 - 0.094 12.3 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 LEM domain KASH_CCD PF14662.6 OAG34131.1 - 0.26 11.1 8.0 0.81 9.5 6.6 2.2 2 1 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH MLTD_N PF06474.12 OAG34133.1 - 0.05 13.8 0.3 0.16 12.2 0.3 1.9 1 0 0 1 1 1 0 MltD lipid attachment motif Dicty_REP PF05086.12 OAG34133.1 - 1.7 6.5 3.6 2 6.3 3.6 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Presenilin PF01080.17 OAG34133.1 - 1.9 7.2 3.2 2.4 6.8 3.2 1.1 1 0 0 1 1 1 0 Presenilin Zn_clus PF00172.18 OAG34134.1 - 1e-06 28.8 8.0 1.7e-06 28.0 8.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PQ-loop PF04193.14 OAG34135.1 - 5.2e-34 115.8 13.6 3.9e-18 65.0 2.1 2.5 2 0 0 2 2 2 2 PQ loop repeat HAGH_C PF16123.5 OAG34135.1 - 4.2e-20 72.0 2.5 7.1e-20 71.3 2.5 1.4 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 OAG34135.1 - 8.6e-13 48.7 0.1 1.4e-08 35.0 0.0 2.6 3 0 0 3 3 3 2 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OAG34135.1 - 0.023 14.2 0.2 0.11 12.0 0.2 2.0 1 1 0 1 1 1 0 Beta-lactamase superfamily domain MtN3_slv PF03083.16 OAG34135.1 - 0.035 14.2 0.1 0.18 11.8 0.1 2.2 2 0 0 2 2 2 0 Sugar efflux transporter for intercellular exchange Catalase PF00199.19 OAG34136.1 - 2.1e-169 563.6 0.0 2.9e-169 563.2 0.0 1.2 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 OAG34136.1 - 1.5e-18 66.7 0.1 3.6e-18 65.5 0.1 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive Catalase_C PF18011.1 OAG34136.1 - 1.2e-10 41.2 0.2 3.5e-10 39.7 0.2 1.9 1 0 0 1 1 1 1 C-terminal domain found in long catalases DJ-1_PfpI PF01965.24 OAG34136.1 - 2.8e-08 33.7 0.0 5.3e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 OAG34136.1 - 0.13 12.0 0.0 0.49 10.0 0.0 2.0 2 0 0 2 2 2 0 ThiJ/PfpI family-like Mei5_like PF17021.5 OAG34136.1 - 0.75 9.9 3.0 1.4 9.0 0.2 2.3 2 0 0 2 2 2 0 Putative double-strand recombination repair-like ETC_C1_NDUFA4 PF04800.12 OAG34138.1 - 1.8e-35 121.0 0.5 3.4e-35 120.2 0.5 1.4 1 0 0 1 1 1 1 ETC complex I subunit conserved region Grg1 PF11034.8 OAG34139.1 - 4.9e-18 65.1 4.4 1.9e-17 63.2 4.4 2.1 1 0 0 1 1 1 1 Glucose-repressible protein Grg1 TRI12 PF06609.13 OAG34140.1 - 9.6e-55 186.1 16.9 1.3e-54 185.7 16.9 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG34140.1 - 3.1e-31 108.6 44.5 6.5e-31 107.5 41.9 2.1 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG34140.1 - 1.6e-08 33.8 13.4 1.6e-08 33.8 13.4 3.6 3 2 0 3 3 3 2 Sugar (and other) transporter MFS_3 PF05977.13 OAG34140.1 - 0.0022 16.4 15.7 0.0099 14.3 2.0 3.2 2 1 1 3 3 3 3 Transmembrane secretion effector TMEM100 PF16311.5 OAG34140.1 - 8.3 6.0 7.0 2.9 7.5 0.0 3.1 3 0 0 3 3 3 0 Transmembrane protein 100 BH4 PF02180.17 OAG34141.1 - 0.19 11.6 1.0 0.37 10.6 1.0 1.5 1 0 0 1 1 1 0 Bcl-2 homology region 4 Aminotran_1_2 PF00155.21 OAG34142.1 - 2.3e-60 204.7 0.0 5.9e-60 203.3 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 OAG34142.1 - 0.024 13.9 0.0 0.035 13.4 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Aminotran_5 PF00266.19 OAG34142.1 - 0.038 13.0 0.0 0.066 12.1 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 OAG34142.1 - 0.048 12.2 0.1 0.26 9.8 0.0 2.0 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme AMP-binding PF00501.28 OAG34143.1 - 1.1e-38 133.0 0.1 1.2e-37 129.5 0.1 2.0 1 1 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 OAG34143.1 - 5.8e-11 42.1 3.8 6.5e-11 42.0 1.5 2.3 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 OAG34143.1 - 0.0002 22.3 0.1 0.00077 20.4 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain F-box PF00646.33 OAG34144.1 - 2e-06 27.5 1.9 8.7e-06 25.5 1.5 2.2 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 OAG34144.1 - 0.00011 22.0 3.3 0.00018 21.3 1.2 2.3 2 0 0 2 2 2 1 F-box-like CYYR1 PF10873.8 OAG34144.1 - 3.1 8.2 6.4 48 4.4 6.4 2.5 2 0 0 2 2 2 0 Cysteine and tyrosine-rich protein 1 SOR_SNZ PF01680.17 OAG34145.1 - 5.8e-107 356.1 5.5 7.6e-107 355.8 5.5 1.1 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.14 OAG34145.1 - 8.2e-07 28.6 11.3 4e-06 26.3 1.4 2.9 1 1 2 3 3 3 2 Thiazole biosynthesis protein ThiG Dus PF01207.17 OAG34145.1 - 0.00031 19.9 0.5 0.11 11.5 0.0 2.5 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) NanE PF04131.14 OAG34145.1 - 0.002 17.3 0.9 0.03 13.5 0.0 2.6 2 1 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase His_biosynth PF00977.21 OAG34145.1 - 0.005 16.3 0.3 0.054 13.0 0.0 2.4 2 1 0 2 2 2 1 Histidine biosynthesis protein IGPS PF00218.21 OAG34145.1 - 0.012 14.8 0.1 0.4 9.8 0.0 2.3 2 0 0 2 2 2 0 Indole-3-glycerol phosphate synthase TetR_C_27 PF17935.1 OAG34145.1 - 0.056 13.5 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain NMO PF03060.15 OAG34145.1 - 0.12 11.7 10.2 0.074 12.4 2.8 2.2 2 0 0 2 2 2 0 Nitronate monooxygenase HNH_repeat PF18780.1 OAG34145.1 - 1.5 8.7 5.1 12 5.8 0.0 3.0 3 0 0 3 3 3 0 Homing endonuclease repeat ORC2 PF04084.14 OAG34146.1 - 8.9e-112 373.3 0.0 1.1e-111 372.9 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 ORC6 PF05460.13 OAG34146.1 - 1.1 8.5 27.0 3.9 6.7 10.2 2.9 1 1 1 2 2 2 0 Origin recognition complex subunit 6 (ORC6) ArgJ PF01960.18 OAG34147.1 - 3.8e-147 489.9 2.5 4.3e-147 489.8 2.5 1.0 1 0 0 1 1 1 1 ArgJ family SecY PF00344.20 OAG34148.1 - 1.6e-71 241.0 8.4 1.9e-71 240.8 8.4 1.0 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 OAG34148.1 - 6.5e-14 51.5 0.1 1.9e-13 50.0 0.1 1.9 1 0 0 1 1 1 1 Plug domain of Sec61p DUF2975 PF11188.8 OAG34148.1 - 9.7 6.1 8.6 1.4 8.8 1.3 3.1 3 1 1 4 4 4 0 Protein of unknown function (DUF2975) SEN1_N PF12726.7 OAG34149.1 - 1.2e-178 595.8 16.2 1.6e-178 595.4 16.2 1.1 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.6 OAG34149.1 - 9.1e-72 242.0 0.3 9.1e-72 242.0 0.3 3.1 3 0 0 3 3 3 2 AAA domain AAA_12 PF13087.6 OAG34149.1 - 8.9e-61 205.0 0.0 1.8e-60 204.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 OAG34149.1 - 3.8e-10 39.8 0.4 5.4e-06 26.3 0.1 2.9 3 0 0 3 3 3 2 AAA domain AAA_19 PF13245.6 OAG34149.1 - 1.1e-07 32.3 0.0 3.1e-07 30.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 OAG34149.1 - 1.1e-05 25.4 0.3 0.038 13.7 0.0 3.4 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.21 OAG34149.1 - 0.00015 21.4 1.7 0.36 10.3 0.0 3.2 2 1 0 3 3 3 2 UvrD/REP helicase N-terminal domain AAA_23 PF13476.6 OAG34149.1 - 0.016 15.7 0.0 0.016 15.7 0.0 2.9 3 0 0 3 3 3 0 AAA domain KASH_CCD PF14662.6 OAG34149.1 - 0.023 14.5 0.9 0.077 12.8 0.9 1.8 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH FIST_C PF10442.9 OAG34149.1 - 0.17 11.9 0.1 0.59 10.1 0.1 2.0 1 0 0 1 1 1 0 FIST C domain AAA_29 PF13555.6 OAG34149.1 - 0.17 11.6 0.3 0.44 10.3 0.3 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain zf-CCHC PF00098.23 OAG34149.1 - 2 8.7 18.6 0.32 11.2 1.6 3.5 3 0 0 3 3 3 0 Zinc knuckle PhoLip_ATPase_C PF16212.5 OAG34150.1 - 2.7e-79 266.4 23.7 2.7e-79 266.4 23.7 2.5 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 OAG34150.1 - 4.6e-18 64.7 1.5 1.2e-17 63.4 1.5 1.7 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 OAG34150.1 - 1.6e-10 41.6 2.3 9e-07 29.4 0.6 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 OAG34150.1 - 2.6e-10 40.3 0.0 9.6e-10 38.4 0.0 1.9 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 OAG34150.1 - 0.0011 18.5 2.4 0.0017 17.9 0.0 2.4 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase_3 PF08282.12 OAG34150.1 - 0.028 14.2 0.3 0.052 13.3 0.3 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase ApbA PF02558.16 OAG34151.1 - 6.5e-28 97.3 0.0 9.6e-28 96.7 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 OAG34151.1 - 1.3e-21 77.1 0.0 2.2e-21 76.4 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal bZIP_1 PF00170.21 OAG34152.1 - 1.2e-07 31.7 7.0 2.1e-07 30.9 7.0 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 OAG34152.1 - 0.0021 18.1 9.6 0.0036 17.4 9.6 1.3 1 0 0 1 1 1 1 Basic region leucine zipper HALZ PF02183.18 OAG34152.1 - 0.0026 17.9 1.7 0.0053 17.0 1.7 1.4 1 0 0 1 1 1 1 Homeobox associated leucine zipper bZIP_Maf PF03131.17 OAG34152.1 - 0.0041 17.6 5.4 0.0069 16.9 5.4 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor GAS PF13851.6 OAG34152.1 - 0.0078 15.6 1.0 0.011 15.1 1.0 1.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Myb_DNA-bind_3 PF12776.7 OAG34152.1 - 0.0093 16.9 0.5 0.024 15.6 0.5 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain SKA2 PF16740.5 OAG34152.1 - 0.043 13.6 0.5 0.079 12.7 0.5 1.3 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 WD40 PF00400.32 OAG34153.1 - 1.8e-19 69.7 22.4 3e-07 31.0 0.3 7.1 7 0 0 7 7 7 4 WD domain, G-beta repeat NLE PF08154.12 OAG34153.1 - 5.9e-17 62.0 0.9 9.6e-17 61.3 0.9 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.8 OAG34153.1 - 0.1 11.2 10.8 4.9 5.7 0.6 3.7 1 1 2 3 3 3 0 Nucleoporin Nup120/160 IL23 PF16649.5 OAG34156.1 - 0.089 12.8 0.0 0.1 12.6 0.0 1.1 1 0 0 1 1 1 0 Interleukin 23 subunit alpha Sod_Fe_C PF02777.18 OAG34157.1 - 2.5e-33 114.3 0.6 5e-33 113.3 0.6 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 OAG34157.1 - 1.8e-16 60.4 2.9 1.8e-16 60.4 2.9 1.7 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Methyltransf_23 PF13489.6 OAG34158.1 - 4.5e-17 62.4 0.0 5.9e-17 62.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG34158.1 - 1.1e-14 55.0 0.0 2.5e-14 53.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG34158.1 - 1.1e-13 51.7 0.1 3.1e-13 50.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG34158.1 - 1.1e-13 51.7 0.1 4.4e-13 49.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG34158.1 - 1.3e-12 47.8 0.0 2e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAG34158.1 - 4.5e-06 26.2 0.0 6.4e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family DREV PF05219.12 OAG34158.1 - 0.0045 16.1 0.0 0.011 14.8 0.0 1.8 1 1 0 1 1 1 1 DREV methyltransferase Methyltransf_32 PF13679.6 OAG34158.1 - 0.099 12.6 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_9 PF08003.11 OAG34158.1 - 0.1 11.5 0.0 0.14 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Peptidase_M16_C PF05193.21 OAG34159.1 - 9.8e-20 71.3 0.0 8.7e-18 65.0 0.0 2.7 2 0 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 OAG34159.1 - 2.4e-06 27.6 0.9 7.1e-06 26.1 0.0 2.2 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) M16C_assoc PF08367.11 OAG34159.1 - 0.026 13.7 3.3 1.2 8.2 0.0 2.4 2 0 0 2 2 2 0 Peptidase M16C associated Lumazine_bd_2 PF12893.7 OAG34159.1 - 0.07 13.8 0.7 0.25 12.0 0.1 2.2 2 1 0 2 2 2 0 Putative lumazine-binding adh_short_C2 PF13561.6 OAG34160.1 - 9.5e-54 182.4 2.1 1.2e-53 182.1 2.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG34160.1 - 2.6e-40 138.0 0.2 3.3e-40 137.6 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG34160.1 - 0.014 15.3 0.5 0.029 14.3 0.5 1.6 1 1 0 1 1 1 0 KR domain Methyltransf_25 PF13649.6 OAG34160.1 - 0.021 15.5 0.1 0.045 14.5 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain adh_short_C2 PF13561.6 OAG34161.1 - 1.7e-35 122.7 2.0 1.9e-35 122.5 2.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG34161.1 - 2e-35 122.0 5.4 2.2e-35 121.9 5.4 1.0 1 0 0 1 1 1 1 short chain dehydrogenase Glu_dehyd_C PF16912.5 OAG34161.1 - 0.0003 20.3 1.0 0.00041 19.9 1.0 1.1 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus 3HCDH_N PF02737.18 OAG34161.1 - 0.0036 17.2 0.6 0.0056 16.6 0.6 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Fumerase_C PF05683.12 OAG34161.1 - 0.03 13.7 0.1 0.052 12.9 0.1 1.4 1 0 0 1 1 1 0 Fumarase C-terminus LeuA_dimer PF08502.10 OAG34161.1 - 0.063 13.2 1.5 0.24 11.3 0.0 2.3 2 1 0 2 2 2 0 LeuA allosteric (dimerisation) domain p450 PF00067.22 OAG34162.1 - 1.5e-66 225.1 0.0 1.9e-66 224.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FMO-like PF00743.19 OAG34163.1 - 9.5e-13 47.4 1.6 1.8e-11 43.2 0.5 3.0 3 1 0 3 3 3 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OAG34163.1 - 1.1e-06 28.8 0.0 2.8e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 OAG34163.1 - 3.1e-06 26.7 0.0 3.6e-05 23.2 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG34163.1 - 7.5e-06 25.3 0.0 0.00026 20.3 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) XET_C PF06955.12 OAG34163.1 - 0.0019 18.0 0.2 0.0057 16.5 0.2 1.8 1 0 0 1 1 1 1 Xyloglucan endo-transglycosylase (XET) C-terminus NAD_binding_9 PF13454.6 OAG34163.1 - 0.0031 17.5 0.1 0.11 12.5 0.0 3.0 2 1 1 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.17 OAG34163.1 - 0.0069 15.6 0.2 0.11 11.8 0.0 2.7 3 0 0 3 3 3 1 Thi4 family HI0933_like PF03486.14 OAG34163.1 - 0.26 9.9 0.0 0.6 8.8 0.0 1.6 1 0 0 1 1 1 0 HI0933-like protein Abhydrolase_3 PF07859.13 OAG34164.1 - 3.1e-34 118.7 0.1 2.6e-18 66.7 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 OAG34164.1 - 2.6e-16 59.5 0.0 7.7e-09 34.9 0.0 2.9 2 1 0 2 2 2 2 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 OAG34164.1 - 0.043 13.3 0.0 0.34 10.4 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family FMO-like PF00743.19 OAG34165.1 - 4e-15 55.2 0.0 1.7e-13 49.9 0.0 2.2 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OAG34165.1 - 2.3e-10 40.2 0.0 9.6e-08 31.6 0.0 2.7 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAG34165.1 - 6.7e-07 28.8 0.0 1.8e-05 24.1 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG34165.1 - 5.4e-05 22.5 0.0 0.0034 16.6 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 OAG34165.1 - 0.00094 19.4 0.0 0.0039 17.4 0.0 2.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAG34165.1 - 0.027 14.1 0.1 1.1 8.7 0.0 2.5 2 1 0 2 2 2 0 FAD dependent oxidoreductase Shikimate_DH PF01488.20 OAG34165.1 - 0.055 13.5 0.0 3.1 7.8 0.0 2.7 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Lycopene_cycl PF05834.12 OAG34165.1 - 0.098 11.7 0.0 0.28 10.2 0.0 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein eIF_4G1 PF12152.8 OAG34165.1 - 0.12 12.6 0.2 0.26 11.5 0.2 1.6 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4G1 Thi4 PF01946.17 OAG34165.1 - 0.14 11.4 0.0 8.1 5.6 0.0 2.3 2 0 0 2 2 2 0 Thi4 family EHN PF06441.12 OAG34166.1 - 5.2e-34 116.9 0.3 1.8e-32 111.9 0.0 2.3 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 OAG34166.1 - 1.3e-11 44.6 0.0 2.3e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold FMO-like PF00743.19 OAG34167.1 - 7.4e-19 67.6 3.4 2.3e-15 56.0 3.4 3.0 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 OAG34167.1 - 1.1e-10 41.2 0.0 1e-07 31.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG34167.1 - 2.9e-10 40.2 0.0 1.2e-09 38.3 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 OAG34167.1 - 9.3e-08 31.7 0.5 0.00042 19.7 0.1 3.1 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAG34167.1 - 9e-05 22.2 0.2 0.013 15.1 0.2 2.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 OAG34167.1 - 0.0003 20.1 0.3 0.0028 16.8 0.0 2.3 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 OAG34167.1 - 0.0051 16.8 0.1 0.036 14.0 0.0 2.4 3 0 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.17 OAG34167.1 - 0.054 12.7 0.0 0.17 11.1 0.0 1.7 2 0 0 2 2 2 0 Thi4 family TRI12 PF06609.13 OAG34168.1 - 2.7e-81 273.8 23.7 3.6e-81 273.4 23.7 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG34168.1 - 1.2e-26 93.4 52.3 1.2e-26 93.4 52.3 3.0 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG34168.1 - 2.6e-10 39.7 10.0 2.6e-10 39.7 10.0 3.6 3 2 1 4 4 4 1 Sugar (and other) transporter DUF3522 PF12036.8 OAG34168.1 - 0.48 10.7 12.2 0.97 9.7 1.3 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3522) Phage_holin_Dp1 PF16938.5 OAG34168.1 - 0.84 9.9 6.5 0.29 11.4 1.4 2.8 2 0 0 2 2 2 0 Putative phage holin Dp-1 Pox_A14 PF05767.12 OAG34168.1 - 2.9 8.1 10.2 0.085 13.0 1.4 2.9 2 1 1 3 3 3 0 Poxvirus virion envelope protein A14 Fungal_trans PF04082.18 OAG34169.1 - 3e-14 52.7 0.0 8.1e-14 51.3 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Abhydrolase_6 PF12697.7 OAG34170.1 - 1.9e-18 67.9 0.2 5.2e-18 66.4 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAG34170.1 - 5e-14 52.6 0.0 5.3e-12 45.9 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAG34170.1 - 1.2e-10 41.1 0.0 1.7e-09 37.3 0.0 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 OAG34170.1 - 0.0018 18.2 0.1 0.0034 17.3 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Mem_trans PF03547.18 OAG34171.1 - 4.2e-19 68.2 1.4 1.8e-18 66.1 1.4 1.8 1 1 0 1 1 1 1 Membrane transport protein Vac_ImportDeg PF09783.9 OAG34172.1 - 9.7e-24 84.0 0.0 3e-23 82.4 0.0 1.9 1 1 0 1 1 1 1 Vacuolar import and degradation protein PHD PF00628.29 OAG34173.1 - 1e-10 41.3 10.5 1.3e-10 41.0 7.2 2.5 2 0 0 2 2 2 1 PHD-finger RXT2_N PF08595.11 OAG34173.1 - 0.29 11.1 2.7 0.2 11.7 0.4 1.9 2 0 0 2 2 2 0 RXT2-like, N-terminal Tannase PF07519.11 OAG34174.1 - 1.8e-84 284.3 0.7 2.4e-84 283.9 0.7 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Sugar_tr PF00083.24 OAG34175.1 - 1.7e-92 310.6 14.5 2.1e-92 310.4 14.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG34175.1 - 1e-25 90.4 50.2 3.4e-22 78.9 26.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.18 OAG34176.1 - 2.8e-19 69.2 0.0 5.1e-19 68.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain AtuA PF07287.11 OAG34177.1 - 5.7e-127 423.3 0.0 7e-127 422.9 0.0 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA FAD_binding_3 PF01494.19 OAG34178.1 - 6.1e-86 288.8 0.0 2.3e-85 286.9 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 OAG34178.1 - 4.9e-56 189.3 0.0 8.9e-56 188.5 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox_2 PF07992.14 OAG34178.1 - 0.00013 21.3 0.1 0.00084 18.6 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAG34178.1 - 0.00049 18.9 0.1 0.00077 18.3 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 OAG34178.1 - 0.0015 17.7 0.0 0.0028 16.8 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 OAG34178.1 - 0.0016 17.8 0.0 0.037 13.3 0.0 2.2 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.12 OAG34178.1 - 0.0019 17.3 0.1 0.0084 15.2 0.0 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 OAG34178.1 - 0.0055 16.0 0.0 0.0086 15.4 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG34178.1 - 0.016 15.4 0.0 0.2 11.9 0.0 2.6 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 OAG34178.1 - 0.074 13.6 0.0 0.26 11.9 0.0 2.0 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 OAG34178.1 - 0.089 12.1 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 OAG34178.1 - 0.13 11.4 0.0 0.23 10.5 0.0 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A TPR_12 PF13424.6 OAG34179.1 - 2.8e-37 126.9 3.8 2.6e-13 50.0 0.1 4.8 3 1 0 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.6 OAG34179.1 - 2e-36 122.9 8.7 2.1e-09 36.9 0.0 7.5 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_19 PF14559.6 OAG34179.1 - 4.6e-12 46.3 2.5 0.0011 19.4 0.1 5.0 1 1 5 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.17 OAG34179.1 - 5.3e-12 44.9 0.0 0.24 11.6 0.0 7.2 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 OAG34179.1 - 2.8e-11 42.7 0.0 0.44 10.9 0.0 6.8 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_6 PF13174.6 OAG34179.1 - 2e-10 40.6 1.4 0.083 13.6 0.0 7.6 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_14 PF13428.6 OAG34179.1 - 7.7e-10 38.8 5.6 0.14 13.0 0.1 7.3 5 2 2 7 7 6 1 Tetratricopeptide repeat PNP_UDP_1 PF01048.20 OAG34179.1 - 6e-09 35.5 3.0 1.1e-07 31.4 3.0 2.5 1 1 0 1 1 1 1 Phosphorylase superfamily TPR_7 PF13176.6 OAG34179.1 - 4.4e-08 32.6 1.3 2.9 8.1 0.0 7.0 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_1 PF00515.28 OAG34179.1 - 6e-08 32.2 0.0 0.18 11.7 0.0 6.0 8 0 0 8 8 7 1 Tetratricopeptide repeat ANAPC3 PF12895.7 OAG34179.1 - 1.2e-07 31.8 0.1 0.15 12.3 0.0 5.1 1 1 5 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.6 OAG34179.1 - 5.2e-07 29.9 3.0 0.44 10.9 0.0 5.8 1 1 5 6 6 6 1 Tetratricopeptide repeat TPR_MalT PF17874.1 OAG34179.1 - 7.8e-07 28.8 1.4 0.00056 19.4 0.1 2.4 1 1 1 2 2 2 2 MalT-like TPR region TPR_17 PF13431.6 OAG34179.1 - 3.1e-06 27.2 0.8 19 5.9 0.0 5.7 5 0 0 5 5 5 0 Tetratricopeptide repeat NB-ARC PF00931.22 OAG34179.1 - 7.6e-06 25.3 0.0 1.7e-05 24.2 0.0 1.6 1 1 0 1 1 1 1 NB-ARC domain TPR_16 PF13432.6 OAG34179.1 - 9.7e-06 26.1 8.3 6.1 7.6 0.3 6.1 5 3 0 5 5 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 OAG34179.1 - 0.00012 21.6 0.0 0.75 9.5 0.0 4.1 4 0 0 4 4 4 1 TPR repeat Vps39_1 PF10366.9 OAG34179.1 - 0.00031 21.0 0.9 10 6.5 0.0 4.7 2 2 2 4 4 4 0 Vacuolar sorting protein 39 domain 1 TPR_4 PF07721.14 OAG34179.1 - 0.0038 17.7 8.0 0.55 11.0 0.1 5.0 4 0 0 4 4 3 1 Tetratricopeptide repeat PPR PF01535.20 OAG34179.1 - 0.0086 16.3 0.1 52 4.4 0.0 4.9 6 0 0 6 6 3 0 PPR repeat TA_inhibitor PF17574.2 OAG34179.1 - 0.022 14.8 0.0 2.3 8.3 0.0 3.4 2 1 1 3 3 3 0 Inhibitor of toxin/antitoxin system (Gp4.5) AAA_16 PF13191.6 OAG34179.1 - 0.076 13.4 0.4 1.2 9.5 0.0 2.9 2 1 1 3 3 2 0 AAA ATPase domain zf-ribbon_3 PF13248.6 OAG34179.1 - 0.46 10.0 3.8 0.88 9.1 3.8 1.5 1 0 0 1 1 1 0 zinc-ribbon domain BTAD PF03704.17 OAG34179.1 - 5.8 7.3 17.4 5.8 7.3 1.6 4.9 4 2 1 5 5 4 0 Bacterial transcriptional activator domain DUF3425 PF11905.8 OAG34180.1 - 3.9e-10 39.8 7.0 3.9e-09 36.5 7.0 2.8 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) MFS_1 PF07690.16 OAG34182.1 - 3.6e-34 118.2 65.9 2.3e-22 79.4 35.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Ldh_1_N PF00056.23 OAG34183.1 - 4.1e-30 104.7 0.0 5.7e-30 104.2 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 OAG34183.1 - 7.8e-15 55.2 0.0 1.2e-14 54.6 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain TrkA_N PF02254.18 OAG34183.1 - 0.021 15.1 0.1 0.038 14.2 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain F420_oxidored PF03807.17 OAG34183.1 - 0.037 14.6 0.1 0.11 13.1 0.1 1.9 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DAO PF01266.24 OAG34183.1 - 0.065 12.8 2.3 0.095 12.3 0.5 1.9 1 1 1 2 2 2 0 FAD dependent oxidoreductase Semialdhyde_dh PF01118.24 OAG34183.1 - 0.11 13.0 0.0 0.23 11.9 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain PPDK_N PF01326.19 OAG34184.1 - 3e-113 378.4 0.0 4.4e-113 377.9 0.0 1.2 1 0 0 1 1 1 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain PEP-utilizers_C PF02896.18 OAG34184.1 - 1.1e-60 205.3 0.0 1.7e-60 204.6 0.0 1.2 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PEP-utilizers PF00391.23 OAG34184.1 - 1.1e-25 89.1 1.0 2.9e-25 87.8 1.0 1.8 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain zf-C2H2 PF00096.26 OAG34185.1 - 6.2e-07 29.5 17.0 3e-05 24.2 2.7 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OAG34185.1 - 4.2e-05 23.8 3.8 4.2e-05 23.8 3.8 2.5 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 OAG34185.1 - 0.00011 22.8 1.8 0.00011 22.8 1.8 3.2 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OAG34185.1 - 0.0015 18.7 0.7 0.0015 18.7 0.7 1.8 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 OAG34185.1 - 0.018 15.3 3.5 0.063 13.6 3.6 1.8 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-C2H2_6 PF13912.6 OAG34185.1 - 0.054 13.5 1.7 0.12 12.4 1.7 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger zf-TRAF PF02176.18 OAG34185.1 - 0.16 12.7 11.0 0.26 12.0 2.6 3.3 3 0 0 3 3 3 0 TRAF-type zinc finger GAGE PF05831.11 OAG34185.1 - 2 9.0 7.8 1.9 9.1 0.5 2.8 2 0 0 2 2 2 0 GAGE protein Fungal_trans PF04082.18 OAG34186.1 - 3.8e-20 72.0 0.0 1.2e-19 70.4 0.0 1.7 1 1 1 2 2 2 1 Fungal specific transcription factor domain UCR_hinge PF02320.16 OAG34186.1 - 0.17 12.1 0.3 0.41 10.9 0.3 1.5 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein Fungal_trans PF04082.18 OAG34187.1 - 3.5e-29 101.7 0.1 1.2e-28 99.9 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG34187.1 - 1.8e-09 37.5 11.3 3.2e-09 36.8 11.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 OAG34188.1 - 2.6e-33 115.4 38.4 1.5e-30 106.4 18.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG34188.1 - 4.5e-08 32.4 3.2 9.5e-08 31.3 3.2 1.5 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.7 OAG34188.1 - 0.0012 17.8 12.7 1.4 7.7 12.7 2.7 1 1 0 1 1 1 1 MFS_1 like family CoA_transf_3 PF02515.17 OAG34189.1 - 1.6e-98 330.2 0.2 1.8e-96 323.5 0.0 2.0 1 1 1 2 2 2 2 CoA-transferase family III Fungal_trans PF04082.18 OAG34190.1 - 1e-21 77.2 0.2 1.6e-21 76.5 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG34190.1 - 3.9e-07 30.1 5.0 7.2e-07 29.2 5.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Phage_Coat_Gp8 PF05371.12 OAG34190.1 - 0.19 11.6 0.1 0.38 10.6 0.1 1.4 1 0 0 1 1 1 0 Phage major coat protein, Gp8 zinc_ribbon_6 PF14599.6 OAG34190.1 - 0.34 11.0 2.4 0.87 9.6 2.4 1.7 1 0 0 1 1 1 0 Zinc-ribbon Peptidase_C14 PF00656.22 OAG34191.1 - 4.8e-32 111.9 0.0 9.9e-32 110.8 0.0 1.4 1 1 0 1 1 1 1 Caspase domain Pilin_N PF07790.11 OAG34192.1 - 0.016 16.1 1.0 0.035 15.0 1.0 1.6 1 0 0 1 1 1 0 Archaeal Type IV pilin, N-terminal SP_C-Propep PF08999.10 OAG34192.1 - 0.053 13.3 0.1 0.13 12.1 0.1 1.6 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide DUF5326 PF17260.2 OAG34192.1 - 0.079 13.1 1.9 0.15 12.2 1.9 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5326) DUF3169 PF11368.8 OAG34192.1 - 0.097 12.2 0.5 0.16 11.4 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) Rick_17kDa_Anti PF05433.15 OAG34192.1 - 0.14 12.1 5.8 0.24 11.3 5.8 1.3 1 0 0 1 1 1 0 Glycine zipper 2TM domain DUF1667 PF07892.11 OAG34193.1 - 0.025 14.6 1.1 0.041 13.9 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1667) Presenilin PF01080.17 OAG34194.1 - 1.2 7.9 3.7 1.4 7.6 3.7 1.0 1 0 0 1 1 1 0 Presenilin Ish1 PF10281.9 OAG34195.1 - 3.9e-94 308.7 22.7 1.7e-14 53.8 0.0 7.5 7 0 0 7 7 7 7 Putative stress-responsive nuclear envelope protein HeH PF12949.7 OAG34195.1 - 2.4e-13 49.5 0.1 0.00046 19.8 0.0 6.2 6 0 0 6 6 6 2 HeH/LEM domain SAP PF02037.27 OAG34195.1 - 5.1e-11 42.1 0.0 0.17 11.7 0.0 6.9 7 0 0 7 7 7 4 SAP domain ANAPC2 PF08672.11 OAG34195.1 - 7e-06 26.5 0.9 35 5.0 0.0 6.5 7 0 0 7 7 7 0 Anaphase promoting complex (APC) subunit 2 Slx4 PF09494.10 OAG34195.1 - 2.6e-05 24.1 0.4 50 3.9 0.0 5.8 7 0 0 7 7 7 0 Slx4 endonuclease LEM PF03020.15 OAG34195.1 - 8.6e-05 22.0 0.0 3.6 7.2 0.0 4.5 4 0 0 4 4 4 2 LEM domain SAM_2 PF07647.17 OAG34195.1 - 0.00015 21.8 2.5 25 5.0 0.0 6.0 6 0 0 6 6 6 0 SAM domain (Sterile alpha motif) Thymopoietin PF08198.11 OAG34195.1 - 0.00021 20.8 0.1 12 5.6 0.0 4.4 4 0 0 4 4 4 2 Thymopoietin protein Homeobox_KN PF05920.11 OAG34195.1 - 0.11 12.5 0.9 11 6.0 0.1 4.0 4 0 0 4 4 4 0 Homeobox KN domain SAP30_Sin3_bdg PF13867.6 OAG34195.1 - 0.12 12.8 6.1 0.78 10.1 0.1 4.3 6 0 0 6 6 6 0 Sin3 binding region of histone deacetylase complex subunit SAP30 DUF2795 PF11387.8 OAG34195.1 - 0.18 12.0 6.8 8.6 6.7 0.1 4.6 5 0 0 5 5 5 0 Protein of unknown function (DUF2795) Cyt-b5 PF00173.28 OAG34196.1 - 1.2e-13 51.0 0.0 2.2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Sugar_tr PF00083.24 OAG34197.1 - 1.3e-47 162.7 9.2 4.3e-47 161.0 9.2 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG34197.1 - 7.4e-26 90.9 14.2 2e-25 89.5 14.5 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.6 OAG34197.1 - 0.0098 14.5 16.3 0.013 14.1 3.5 2.5 3 0 0 3 3 3 2 MFS/sugar transport protein Lum_binding PF00677.17 OAG34198.1 - 1.7e-43 146.5 0.3 1.9e-20 72.6 0.1 2.9 2 0 0 2 2 2 2 Lumazine binding domain SesA PF17107.5 OAG34198.1 - 0.0084 16.3 0.2 0.017 15.3 0.2 1.5 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases Utp12 PF04003.12 OAG34198.1 - 0.022 15.0 0.6 0.071 13.4 0.1 2.0 2 0 0 2 2 2 0 Dip2/Utp12 Family Fungal_trans PF04082.18 OAG34199.1 - 1.1e-08 34.4 0.9 2.4e-08 33.3 0.9 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain NMO PF03060.15 OAG34200.1 - 6e-32 111.3 0.1 6.8e-32 111.2 0.1 1.0 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 OAG34200.1 - 0.0046 16.0 0.4 0.0069 15.4 0.4 1.3 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 OAG34200.1 - 0.0049 15.9 0.1 0.0066 15.5 0.1 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NAD_binding_8 PF13450.6 OAG34201.1 - 1.6e-13 50.7 0.0 3.2e-13 49.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.19 OAG34201.1 - 3.7e-12 45.4 1.3 1.8e-09 36.6 0.5 2.5 1 1 1 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_9 PF13454.6 OAG34201.1 - 3.3e-05 23.9 0.0 0.0017 18.3 0.0 2.9 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.24 OAG34201.1 - 7.7e-05 22.4 0.0 0.011 15.4 0.0 2.5 2 1 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.17 OAG34201.1 - 0.0061 15.8 0.2 0.14 11.4 0.0 2.5 3 0 0 3 3 3 1 Thi4 family APP_N PF02177.16 OAG34201.1 - 0.0064 16.8 0.4 0.021 15.2 0.4 1.8 1 0 0 1 1 1 1 Amyloid A4 N-terminal heparin-binding K_oxygenase PF13434.6 OAG34201.1 - 0.0064 15.7 0.1 2.6 7.1 0.0 3.5 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 OAG34201.1 - 0.021 14.1 0.0 0.33 10.1 0.0 2.6 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Cyclase PF04199.13 OAG34202.1 - 1.1e-15 58.0 0.0 1.7e-15 57.4 0.0 1.3 1 1 0 1 1 1 1 Putative cyclase AMP-binding PF00501.28 OAG34203.1 - 5.2e-83 279.0 0.0 7.8e-83 278.4 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG34203.1 - 9.6e-17 61.7 0.2 2.9e-16 60.2 0.1 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain MFS_1 PF07690.16 OAG34204.1 - 2.6e-20 72.6 44.9 1.2e-15 57.3 27.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily HATPase_c PF02518.26 OAG34205.1 - 1.3e-21 77.2 0.0 4.5e-21 75.5 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 OAG34205.1 - 9.7e-20 70.8 2.1 1.5e-19 70.2 0.8 2.1 2 0 0 2 2 2 1 Response regulator receiver domain PAS_4 PF08448.10 OAG34205.1 - 5.3e-13 49.2 0.0 2.2e-09 37.5 0.0 2.9 2 0 0 2 2 2 2 PAS fold PAS PF00989.25 OAG34205.1 - 2.2e-12 47.0 0.2 1.5e-11 44.3 0.0 2.6 3 0 0 3 3 3 1 PAS fold PAS_9 PF13426.7 OAG34205.1 - 1.6e-09 38.0 0.0 3e-07 30.6 0.0 3.0 3 0 0 3 3 2 1 PAS domain HisKA PF00512.25 OAG34205.1 - 3.3e-09 36.6 0.2 8.4e-09 35.3 0.2 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.12 OAG34205.1 - 3.9e-08 33.5 0.1 1e-07 32.2 0.1 1.8 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 OAG34205.1 - 0.004 17.1 0.0 0.015 15.3 0.0 2.0 1 0 0 1 1 1 1 PAS domain GAF PF01590.26 OAG34205.1 - 0.0061 17.2 0.0 0.035 14.7 0.0 2.4 1 1 0 1 1 1 1 GAF domain dCache_1 PF02743.18 OAG34205.1 - 0.011 15.5 0.0 0.026 14.3 0.0 1.5 1 0 0 1 1 1 0 Cache domain GAF_2 PF13185.6 OAG34205.1 - 0.043 14.1 0.0 0.48 10.7 0.0 2.4 2 0 0 2 2 2 0 GAF domain GAF_3 PF13492.6 OAG34205.1 - 0.13 12.7 0.0 0.34 11.3 0.0 1.8 1 0 0 1 1 1 0 GAF domain Na_Ca_ex PF01699.24 OAG34206.1 - 4.8e-36 124.0 46.5 3.5e-19 69.3 21.4 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Rib_recp_KP_reg PF05104.12 OAG34206.1 - 0.00031 21.8 8.3 0.00031 21.8 8.3 2.4 2 1 0 2 2 2 1 Ribosome receptor lysine/proline rich region Coilin_N PF15862.5 OAG34206.1 - 3 7.6 16.9 0.39 10.5 0.2 2.4 2 0 0 2 2 2 0 Coilin N-terminus AA_permease_2 PF13520.6 OAG34207.1 - 1e-63 215.7 46.2 1.2e-63 215.4 46.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAG34207.1 - 2.8e-13 49.3 36.8 4e-13 48.8 36.8 1.2 1 0 0 1 1 1 1 Amino acid permease Glycophorin_A PF01102.18 OAG34207.1 - 0.0087 16.3 0.0 0.033 14.4 0.0 1.9 1 0 0 1 1 1 1 Glycophorin A Pox_A14 PF05767.12 OAG34208.1 - 2 8.7 5.5 0.7 10.1 0.4 2.6 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 Methyltransf_2 PF00891.18 OAG34209.1 - 6.9e-10 38.6 0.0 1.1e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_23 PF13489.6 OAG34209.1 - 0.0069 16.2 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MFS_1 PF07690.16 OAG34210.1 - 1.3e-20 73.6 38.8 1.3e-20 73.6 38.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily adh_short PF00106.25 OAG34211.1 - 1.6e-49 168.0 0.1 2e-49 167.7 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG34211.1 - 2.2e-49 168.1 0.1 2.9e-49 167.7 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG34211.1 - 7.8e-08 32.4 0.2 1.5e-07 31.5 0.2 1.5 1 1 0 1 1 1 1 KR domain FMO-like PF00743.19 OAG34212.1 - 3.3e-14 52.2 0.4 1.5e-13 50.0 0.4 1.9 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OAG34212.1 - 7.2e-10 38.6 0.0 4.4e-08 32.7 0.0 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG34212.1 - 2.9e-09 36.6 0.2 1.2e-07 31.2 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 OAG34212.1 - 4e-08 32.8 0.0 3.9e-06 26.3 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG34212.1 - 1.4e-06 28.4 0.0 4.6e-06 26.8 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 OAG34212.1 - 0.0003 20.8 0.1 0.1 12.6 0.0 3.6 3 1 1 4 4 4 1 FAD-NAD(P)-binding RAP PF08373.10 OAG34212.1 - 0.005 16.9 0.3 0.013 15.6 0.3 1.6 1 0 0 1 1 1 1 RAP domain NAD_binding_7 PF13241.6 OAG34212.1 - 0.077 13.4 0.1 13 6.3 0.0 2.7 2 0 0 2 2 2 0 Putative NAD(P)-binding Shikimate_DH PF01488.20 OAG34212.1 - 0.11 12.5 0.0 7.3 6.6 0.0 2.7 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase TRI12 PF06609.13 OAG34213.1 - 7.8e-145 483.6 21.4 9.4e-145 483.4 21.4 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG34213.1 - 2.3e-16 59.7 49.3 2.2e-15 56.5 44.5 3.0 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG34213.1 - 8.5e-12 44.7 8.2 8.5e-12 44.7 8.2 2.9 4 0 0 4 4 4 2 Sugar (and other) transporter DUF3784 PF12650.7 OAG34213.1 - 0.0091 16.2 0.0 0.0091 16.2 0.0 5.7 8 0 0 8 8 8 1 Domain of unknown function (DUF3784) EamA PF00892.20 OAG34213.1 - 0.037 14.2 0.4 0.037 14.2 0.4 5.1 5 1 1 6 6 6 0 EamA-like transporter family DUF3040 PF11239.8 OAG34213.1 - 0.77 10.1 0.0 0.77 10.1 0.0 4.5 3 1 1 4 4 4 0 Protein of unknown function (DUF3040) 2OG-FeII_Oxy PF03171.20 OAG34214.1 - 1.2e-13 51.4 0.0 1.9e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 OAG34214.1 - 4.4e-05 24.2 0.0 0.00016 22.4 0.0 1.8 1 1 1 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal adh_short_C2 PF13561.6 OAG34215.1 - 1.1e-33 116.7 0.1 1.9e-33 116.0 0.1 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG34215.1 - 2.4e-26 92.4 0.3 3.5e-26 91.9 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG34215.1 - 5.1e-07 29.8 0.1 8.7e-07 29.0 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG34215.1 - 0.002 17.6 1.1 0.0077 15.7 1.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DFP PF04127.15 OAG34215.1 - 0.012 15.4 1.9 0.16 11.8 1.9 2.1 1 1 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Tegument_dsDNA PF12818.7 OAG34215.1 - 0.059 12.5 0.0 1.2 8.3 0.0 2.1 2 0 0 2 2 2 0 dsDNA viral tegument protein SKI PF01202.22 OAG34216.1 - 4.3e-12 46.4 0.0 5.7e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 Shikimate kinase AAA_33 PF13671.6 OAG34216.1 - 7e-11 42.5 0.0 1.1e-10 41.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 OAG34216.1 - 1e-08 35.8 0.1 3.9e-08 33.9 0.1 1.9 1 1 0 1 1 1 1 AAA domain dNK PF01712.19 OAG34216.1 - 6.8e-05 22.8 0.2 0.043 13.7 0.0 2.2 1 1 0 2 2 2 2 Deoxynucleoside kinase Rad17 PF03215.15 OAG34216.1 - 6.9e-05 22.9 0.0 0.00012 22.1 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_17 PF13207.6 OAG34216.1 - 0.00014 22.3 0.0 0.00069 20.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 OAG34216.1 - 0.0019 18.0 0.0 0.0037 17.0 0.0 1.5 1 0 0 1 1 1 1 Cytidylate kinase AAA PF00004.29 OAG34216.1 - 0.005 17.3 0.0 0.01 16.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Thermopsin PF05317.11 OAG34216.1 - 0.0073 15.8 0.0 0.015 14.8 0.0 1.5 1 0 0 1 1 1 1 Thermopsin Ploopntkinase1 PF18748.1 OAG34216.1 - 0.013 15.1 0.0 1.8 8.1 0.0 2.2 2 0 0 2 2 2 0 P-loop Nucleotide Kinase1 Zeta_toxin PF06414.12 OAG34216.1 - 0.022 14.0 0.0 0.04 13.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_22 PF13401.6 OAG34216.1 - 0.025 14.8 0.1 0.059 13.6 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 OAG34216.1 - 0.026 14.9 0.0 0.048 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain RNA_helicase PF00910.22 OAG34216.1 - 0.033 14.6 0.0 0.054 13.9 0.0 1.4 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.12 OAG34216.1 - 0.041 13.8 0.0 0.22 11.4 0.0 2.1 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.6 OAG34216.1 - 0.053 13.8 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain GFO_IDH_MocA PF01408.22 OAG34217.1 - 2.7e-17 63.7 0.0 8.3e-16 58.9 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 OAG34217.1 - 4.4e-07 29.9 0.0 1e-06 28.7 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Fungal_trans PF04082.18 OAG34218.1 - 7.2e-13 48.2 0.3 1.8e-12 46.9 0.1 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG34218.1 - 0.022 14.9 2.3 0.038 14.1 2.3 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain MSA_2 PF00985.17 OAG34218.1 - 0.18 12.2 4.0 0.62 10.4 4.0 1.9 1 0 0 1 1 1 0 Merozoite Surface Antigen 2 (MSA-2) family FMO-like PF00743.19 OAG34219.1 - 3.5e-23 81.8 0.0 3.7e-17 61.9 0.1 2.8 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OAG34219.1 - 2e-19 70.0 0.0 1.2e-18 67.4 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAG34219.1 - 2.6e-12 46.6 0.0 3.1e-10 39.8 0.0 2.7 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG34219.1 - 3.5e-08 33.0 0.0 2.7e-06 26.8 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 OAG34219.1 - 3.7e-06 27.4 0.7 0.18 12.4 0.0 3.9 4 0 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG34219.1 - 9.9e-06 25.7 0.0 0.012 15.8 0.0 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 OAG34219.1 - 1.5e-05 24.6 0.0 1.4 8.2 0.1 3.3 3 0 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 OAG34219.1 - 1.8e-05 24.2 0.0 0.14 11.3 0.1 3.1 3 0 0 3 3 3 2 FAD binding domain 2-Hacid_dh_C PF02826.19 OAG34219.1 - 2.8e-05 23.6 0.0 0.0073 15.7 0.0 2.6 3 0 0 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 OAG34219.1 - 0.0026 16.9 0.1 0.022 13.8 0.3 2.4 2 1 0 2 2 2 1 Lycopene cyclase protein HI0933_like PF03486.14 OAG34219.1 - 0.0028 16.4 0.0 0.27 9.9 0.1 2.6 3 0 0 3 3 3 1 HI0933-like protein DAO PF01266.24 OAG34219.1 - 0.003 17.2 1.6 1.6 8.3 0.1 3.5 2 2 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 OAG34219.1 - 0.004 17.1 0.6 1.3 8.9 0.0 3.1 2 1 1 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.17 OAG34219.1 - 0.017 14.3 0.0 5.1 6.3 0.0 2.3 2 0 0 2 2 2 0 Thi4 family GIDA PF01134.22 OAG34219.1 - 0.02 14.0 0.1 1.5 7.9 0.0 2.5 3 0 0 3 3 3 0 Glucose inhibited division protein A FAD_binding_2 PF00890.24 OAG34219.1 - 0.039 13.0 0.0 0.4 9.7 0.2 2.4 3 0 0 3 3 3 0 FAD binding domain F420_oxidored PF03807.17 OAG34219.1 - 0.12 12.9 0.0 0.54 10.9 0.0 2.1 2 0 0 2 2 1 0 NADP oxidoreductase coenzyme F420-dependent Lactonase PF10282.9 OAG34220.1 - 7.7e-33 114.2 0.0 1.1e-32 113.7 0.0 1.1 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Thioredoxin_8 PF13905.6 OAG34220.1 - 0.036 14.4 0.0 0.069 13.5 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like Sugar_tr PF00083.24 OAG34221.1 - 1.8e-107 360.0 20.9 2.3e-107 359.7 20.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG34221.1 - 4.3e-27 95.0 36.2 2e-19 69.7 17.5 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 OAG34221.1 - 9.4e-07 27.6 2.0 9.4e-07 27.6 2.0 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF1028 PF06267.12 OAG34221.1 - 0.2 11.4 0.3 0.35 10.6 0.3 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF1028) UNC-93 PF05978.16 OAG34221.1 - 0.24 11.1 16.9 0.08 12.7 4.7 3.0 3 0 0 3 3 3 0 Ion channel regulatory protein UNC-93 OrsD PF12013.8 OAG34222.1 - 1.1e-09 38.7 1.3 1.1e-09 38.7 0.2 1.5 2 0 0 2 2 2 1 Orsellinic acid/F9775 biosynthesis cluster protein D DUF4100 PF13352.6 OAG34224.1 - 0.023 14.5 0.0 0.036 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4100) LapA_dom PF06305.11 OAG34224.1 - 0.22 11.4 1.4 0.85 9.5 0.9 2.3 1 1 1 2 2 2 0 Lipopolysaccharide assembly protein A domain LRR_6 PF13516.6 OAG34226.1 - 1.4e-11 43.5 2.3 0.063 13.4 0.0 7.0 7 0 0 7 7 7 3 Leucine Rich repeat LRR_4 PF12799.7 OAG34226.1 - 1.7 9.2 6.6 9.3 6.8 0.3 4.0 2 1 2 4 4 4 0 Leucine Rich repeats (2 copies) 2-Hacid_dh_C PF02826.19 OAG34227.1 - 0.038 13.3 0.0 0.058 12.8 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 OAG34227.1 - 0.048 13.8 0.0 0.08 13.1 0.0 1.4 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 OAG34227.1 - 0.15 11.6 0.0 0.39 10.3 0.0 1.6 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Pyr_redox_2 PF07992.14 OAG34227.1 - 0.19 10.9 0.0 0.3 10.3 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 OAG34227.1 - 0.19 11.6 0.0 0.27 11.1 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Glyco_transf_21 PF13506.6 OAG34228.1 - 0.02 14.3 0.0 0.022 14.2 0.0 1.1 1 0 0 1 1 1 0 Glycosyl transferase family 21 Cyclin PF08613.11 OAG34233.1 - 2.4e-05 24.7 0.2 8.6e-05 23.0 0.0 2.1 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 OAG34233.1 - 0.0085 15.8 0.0 0.021 14.6 0.0 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Acetyltransf_1 PF00583.25 OAG34234.1 - 6e-11 42.6 0.0 8.8e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OAG34234.1 - 4.8e-08 33.0 0.0 7.8e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OAG34234.1 - 5.9e-07 29.8 0.1 9.1e-07 29.2 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain His_Phos_2 PF00328.22 OAG34235.1 - 1.2e-41 143.3 0.0 1.4e-41 143.1 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DHDPS PF00701.22 OAG34236.1 - 5.7e-37 127.0 0.0 6.6e-37 126.8 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family TRP PF06011.12 OAG34237.1 - 2.9e-115 385.4 23.3 3.9e-115 385.0 23.3 1.2 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 OAG34237.1 - 9.5e-41 139.4 0.3 1.5e-40 138.8 0.3 1.3 1 0 0 1 1 1 1 ML-like domain DUF3278 PF11683.8 OAG34237.1 - 0.55 10.3 10.0 0.36 10.9 0.2 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3278) DUF3425 PF11905.8 OAG34238.1 - 0.0018 18.2 0.3 0.0048 16.9 0.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 OAG34238.1 - 0.0048 17.0 1.6 0.0048 17.0 1.6 2.1 2 0 0 2 2 2 1 bZIP transcription factor zf-RRN7 PF11781.8 OAG34241.1 - 0.17 11.6 0.4 0.17 11.6 0.4 2.1 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 TauD PF02668.16 OAG34242.1 - 3.2e-53 181.3 0.2 3.7e-53 181.0 0.2 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family TPR_11 PF13414.6 OAG34242.1 - 0.033 13.9 0.0 0.078 12.7 0.0 1.6 1 0 0 1 1 1 0 TPR repeat Ank_2 PF12796.7 OAG34243.1 - 7.7e-58 193.1 0.2 1.9e-10 41.2 0.1 6.8 4 1 0 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAG34243.1 - 1.8e-45 152.7 1.3 2.2e-06 28.1 0.0 11.1 4 4 9 13 13 13 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG34243.1 - 7e-44 142.8 4.8 0.0006 20.1 0.0 14.6 15 0 0 15 15 15 11 Ankyrin repeat Ank_5 PF13857.6 OAG34243.1 - 3.2e-42 142.0 2.1 1.2e-05 25.5 0.0 9.2 6 2 4 10 10 10 8 Ankyrin repeats (many copies) Ank PF00023.30 OAG34243.1 - 3e-28 97.0 6.5 0.029 14.8 0.0 13.4 13 1 1 14 14 14 7 Ankyrin repeat DUF5618 PF18498.1 OAG34245.1 - 0.23 11.7 0.3 0.37 11.0 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5618) MFS_1 PF07690.16 OAG34247.1 - 4.6e-45 154.1 47.6 2e-35 122.4 35.7 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily FA_hydroxylase PF04116.13 OAG34248.1 - 1.7e-26 93.1 17.2 1.7e-26 93.1 17.2 2.2 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily Pterin_4a PF01329.19 OAG34249.1 - 4.8e-12 45.9 0.0 9e-12 45.0 0.0 1.4 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase DUF3471 PF11954.8 OAG34249.1 - 0.21 12.1 0.0 0.36 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3471) Inositol_P PF00459.25 OAG34251.1 - 5.3e-61 206.5 0.1 7e-61 206.1 0.1 1.1 1 0 0 1 1 1 1 Inositol monophosphatase family AAA PF00004.29 OAG34252.1 - 3.4e-44 150.5 0.0 5.3e-44 149.9 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OAG34252.1 - 3.7e-15 55.4 0.1 7.7e-15 54.4 0.1 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 OAG34252.1 - 2e-07 31.3 0.0 3.4e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 OAG34252.1 - 7.4e-07 29.7 0.1 4.5e-05 23.9 0.0 2.8 2 1 0 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 OAG34252.1 - 7.6e-07 29.2 0.0 1.9e-06 27.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Prot_ATP_ID_OB PF16450.5 OAG34252.1 - 3.1e-06 27.0 2.3 8.1e-06 25.7 2.3 1.8 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_22 PF13401.6 OAG34252.1 - 3e-05 24.3 0.2 0.0063 16.8 0.0 2.4 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 OAG34252.1 - 7e-05 22.6 0.0 0.00014 21.7 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 OAG34252.1 - 0.0011 18.7 0.0 0.002 17.9 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.13 OAG34252.1 - 0.0011 18.2 0.0 0.0023 17.2 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 OAG34252.1 - 0.0018 18.4 0.0 0.0036 17.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 OAG34252.1 - 0.0051 17.4 0.0 0.029 14.9 0.0 2.3 3 0 0 3 3 2 1 AAA domain AAA_3 PF07726.11 OAG34252.1 - 0.0062 16.4 0.0 0.015 15.1 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 OAG34252.1 - 0.0076 15.6 0.1 0.018 14.4 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI ATPase PF06745.13 OAG34252.1 - 0.0077 15.6 0.0 0.019 14.3 0.0 1.6 1 0 0 1 1 1 1 KaiC AAA_28 PF13521.6 OAG34252.1 - 0.011 15.9 0.0 0.02 15.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 OAG34252.1 - 0.012 15.6 0.0 0.021 14.8 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 OAG34252.1 - 0.019 14.1 0.0 0.033 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.26 OAG34252.1 - 0.023 14.4 0.0 0.096 12.4 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain PhoH PF02562.16 OAG34252.1 - 0.027 13.9 0.0 0.098 12.1 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein AAA_7 PF12775.7 OAG34252.1 - 0.029 13.9 0.0 0.048 13.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region HR1 PF02185.16 OAG34252.1 - 0.032 14.4 0.9 0.081 13.0 0.9 1.7 1 0 0 1 1 1 0 Hr1 repeat RNA_helicase PF00910.22 OAG34252.1 - 0.04 14.3 0.0 0.069 13.5 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.6 OAG34252.1 - 0.043 13.8 0.0 0.073 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 OAG34252.1 - 0.044 13.5 0.0 0.1 12.3 0.0 1.6 2 0 0 2 2 2 0 AAA domain Prot_ATP_OB_N PF17758.1 OAG34252.1 - 0.065 12.9 0.1 0.24 11.1 0.1 2.0 1 1 0 1 1 1 0 Proteasomal ATPase OB N-terminal domain AAA_25 PF13481.6 OAG34252.1 - 0.067 12.8 0.1 0.21 11.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 OAG34252.1 - 0.091 11.8 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF2072 PF09845.9 OAG34252.1 - 0.14 12.4 0.1 0.25 11.6 0.1 1.4 1 0 0 1 1 1 0 Zn-ribbon containing protein NACHT PF05729.12 OAG34252.1 - 0.15 12.0 0.0 0.45 10.4 0.0 1.8 2 0 0 2 2 2 0 NACHT domain Zeta_toxin PF06414.12 OAG34252.1 - 0.16 11.2 0.0 0.28 10.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Na_Ca_ex PF01699.24 OAG34253.1 - 2.2e-21 76.4 27.4 1.1e-14 54.7 11.5 4.4 5 0 0 5 5 5 2 Sodium/calcium exchanger protein YccF PF03733.13 OAG34253.1 - 9.3e-13 48.7 14.5 9.3e-13 48.7 14.5 4.9 6 0 0 6 6 6 1 Inner membrane component domain F-box-like PF12937.7 OAG34254.1 - 0.00073 19.4 0.5 0.0022 17.8 0.5 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAG34254.1 - 0.0025 17.7 1.2 0.0063 16.4 1.2 1.7 1 0 0 1 1 1 1 F-box domain Anoctamin PF04547.12 OAG34255.1 - 1.7e-117 393.1 2.8 2e-117 392.8 2.8 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel ABC_membrane PF00664.23 OAG34255.1 - 0.1 12.2 2.8 0.7 9.5 0.0 2.9 3 0 0 3 3 3 0 ABC transporter transmembrane region DUF2207 PF09972.9 OAG34255.1 - 0.11 11.2 2.2 1 8.0 0.0 2.4 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) FMN_dh PF01070.18 OAG34256.1 - 1.8e-112 375.9 0.3 4e-112 374.7 0.3 1.5 1 1 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 OAG34256.1 - 6.5e-06 25.4 0.7 1.3e-05 24.3 0.6 1.5 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 OAG34256.1 - 3.5e-05 23.1 0.2 5.9e-05 22.4 0.2 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase ThiG PF05690.14 OAG34256.1 - 0.00025 20.4 0.1 0.32 10.3 0.0 2.3 1 1 1 2 2 2 2 Thiazole biosynthesis protein ThiG NMO PF03060.15 OAG34256.1 - 0.001 18.6 0.0 0.0014 18.1 0.0 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.21 OAG34256.1 - 0.016 14.6 0.8 0.57 9.6 0.0 2.6 2 1 1 3 3 3 0 Histidine biosynthesis protein IGPS PF00218.21 OAG34256.1 - 0.19 10.9 0.0 0.54 9.4 0.0 1.7 1 1 0 1 1 1 0 Indole-3-glycerol phosphate synthase Thymidylat_synt PF00303.19 OAG34259.1 - 1.6e-105 352.1 0.0 1.9e-105 351.8 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase zf-AN1 PF01428.16 OAG34260.1 - 4.7e-22 77.9 31.1 5.6e-11 42.4 9.9 2.2 2 0 0 2 2 2 2 AN1-like Zinc finger IBR PF01485.21 OAG34260.1 - 0.022 15.0 20.3 0.048 13.9 7.8 2.6 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain C1_4 PF07975.12 OAG34260.1 - 3.2 8.1 19.0 6.2 7.1 7.8 2.6 2 0 0 2 2 2 0 TFIIH C1-like domain Transp_Tc5_C PF04236.15 OAG34260.1 - 5.5 7.4 17.9 2.8 8.4 4.6 2.4 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain zinc_ribbon_4 PF13717.6 OAG34260.1 - 9.2 6.3 9.2 12 5.9 0.9 2.9 2 0 0 2 2 2 0 zinc-ribbon domain ADH_N PF08240.12 OAG34261.1 - 1.6e-24 85.9 0.1 3.4e-24 84.8 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG34261.1 - 3.9e-19 68.9 0.0 3.9e-19 68.9 0.0 2.2 4 0 0 4 4 4 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAG34261.1 - 0.00025 22.1 0.1 0.00077 20.5 0.0 2.0 2 1 0 2 2 2 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 OAG34261.1 - 0.0014 18.1 0.1 0.0025 17.3 0.1 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 OAG34261.1 - 0.009 15.3 1.8 0.014 14.7 1.8 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain IGFBP PF00219.18 OAG34261.1 - 0.12 13.1 0.3 0.12 13.1 0.3 1.8 2 0 0 2 2 2 0 Insulin-like growth factor binding protein FAD_binding_1 PF00667.20 OAG34263.1 - 1.5e-32 113.0 0.0 2.2e-32 112.4 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 OAG34263.1 - 8.8e-32 110.3 0.1 3.7e-31 108.3 0.1 1.9 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.21 OAG34263.1 - 3.8e-16 59.7 0.0 7e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 OAG34263.1 - 0.12 12.6 0.0 0.43 10.8 0.0 1.9 2 0 0 2 2 2 0 Flavodoxin domain Cu_amine_oxid PF01179.20 OAG34264.1 - 7.7e-161 535.6 0.1 9.3e-161 535.3 0.1 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 OAG34264.1 - 1.2e-22 80.2 0.4 1.1e-21 77.1 0.1 2.3 1 1 1 2 2 2 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 OAG34264.1 - 8.1e-09 35.6 0.0 1.5e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain RdgC PF04381.12 OAG34264.1 - 0.075 12.3 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Putative exonuclease, RdgC CAF1 PF04857.20 OAG34265.1 - 6.8e-22 78.0 0.0 1.9e-10 40.4 0.0 2.1 2 0 0 2 2 2 2 CAF1 family ribonuclease WD40 PF00400.32 OAG34266.1 - 0.00035 21.3 0.1 3.2 8.8 0.0 3.3 3 0 0 3 3 3 2 WD domain, G-beta repeat Exo_endo_phos PF03372.23 OAG34267.1 - 4.9e-06 26.2 0.0 9.3e-06 25.3 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family ASH PF15780.5 OAG34267.1 - 0.023 14.9 0.0 0.11 12.7 0.0 2.2 1 1 0 1 1 1 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin F-box PF00646.33 OAG34269.1 - 1.6e-05 24.7 3.2 2.9e-05 23.8 0.2 2.7 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.7 OAG34269.1 - 0.0012 18.6 0.1 0.0027 17.5 0.1 1.6 1 0 0 1 1 1 1 F-box-like MFS_1 PF07690.16 OAG34270.1 - 7.9e-48 163.2 12.6 1.2e-47 162.5 12.6 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG34270.1 - 3e-08 33.0 0.2 3e-08 33.0 0.2 2.4 3 0 0 3 3 3 1 Sugar (and other) transporter OATP PF03137.20 OAG34270.1 - 0.007 14.7 0.2 0.021 13.1 0.2 1.7 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_3 PF05977.13 OAG34270.1 - 6.5 5.0 12.7 0.13 10.7 2.6 2.1 2 0 0 2 2 2 0 Transmembrane secretion effector Pet100 PF09803.9 OAG34271.1 - 9.9e-17 61.2 0.1 1.4e-16 60.7 0.1 1.2 1 0 0 1 1 1 1 Pet100 DUF3618 PF12277.8 OAG34271.1 - 0.032 14.5 2.9 0.053 13.8 2.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3618) MRP-S23 PF10484.9 OAG34271.1 - 0.05 13.9 0.0 0.052 13.8 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal protein S23 SPT_ssu-like PF11779.8 OAG34272.1 - 1.8e-23 81.9 5.0 2.4e-23 81.5 5.0 1.2 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like DUF89 PF01937.19 OAG34273.1 - 7.2e-39 133.7 0.0 8.6e-39 133.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 Iso_dh PF00180.20 OAG34274.1 - 1.4e-79 267.8 0.0 1.7e-79 267.5 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase PTS_EIIC_2 PF13303.6 OAG34274.1 - 0.2 10.6 0.0 0.28 10.2 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase system, EIIC DUF4164 PF13747.6 OAG34275.1 - 0.059 13.7 0.5 0.35 11.2 0.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) Pkinase PF00069.25 OAG34277.1 - 1e-15 57.8 0.0 1.2e-15 57.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG34277.1 - 1.4e-06 27.8 0.0 2.2e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAG34277.1 - 1.9e-05 23.7 0.0 2.8e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OAG34277.1 - 0.00042 20.3 0.0 0.021 14.7 0.0 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 OAG34277.1 - 0.0065 15.8 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pyr_redox_2 PF07992.14 OAG34278.1 - 4.9e-15 55.5 0.0 1.1e-11 44.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 OAG34278.1 - 4e-14 51.9 0.7 3.2e-12 45.6 0.1 2.4 3 0 0 3 3 3 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OAG34278.1 - 1e-10 41.4 0.0 1.8e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG34278.1 - 1.2e-09 37.8 0.0 4.9e-09 35.8 0.0 1.8 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 OAG34278.1 - 4.6e-08 33.2 0.0 1.7e-06 28.2 0.0 3.2 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAG34278.1 - 8.4e-05 22.3 0.0 0.017 14.7 0.0 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OAG34278.1 - 0.0063 15.6 0.0 0.011 14.8 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 OAG34278.1 - 0.012 15.6 3.2 10 6.1 0.1 4.1 3 1 1 4 4 4 0 FAD-NAD(P)-binding FAD_oxidored PF12831.7 OAG34278.1 - 0.016 14.6 0.0 0.035 13.5 0.0 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 OAG34278.1 - 0.016 13.9 0.6 0.46 9.1 0.0 2.7 3 0 0 3 3 3 0 HI0933-like protein GIDA PF01134.22 OAG34278.1 - 0.074 12.1 0.6 1.8 7.5 0.0 2.7 3 0 0 3 3 3 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 OAG34278.1 - 0.42 9.6 1.6 0.68 8.9 0.2 2.1 2 1 0 2 2 2 0 Lycopene cyclase protein Beta-lactamase PF00144.24 OAG34279.1 - 1.9e-42 145.7 0.0 4.3e-42 144.5 0.0 1.5 1 1 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.20 OAG34279.1 - 0.2 11.1 0.0 0.3 10.5 0.0 1.2 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase Zn_clus PF00172.18 OAG34280.1 - 1e-05 25.5 13.4 5.3e-05 23.3 13.4 2.1 1 1 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HET PF06985.11 OAG34281.1 - 2.8e-08 34.2 7.0 3.3e-06 27.5 1.3 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) SAM_decarbox PF01536.16 OAG34282.1 - 2.4e-131 438.0 0.0 2.9e-131 437.7 0.0 1.1 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase ParA PF10609.9 OAG34283.1 - 6.9e-82 274.6 0.1 1.9e-81 273.2 0.1 1.7 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 OAG34283.1 - 4.6e-10 39.6 0.0 1.5e-09 38.0 0.0 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.11 OAG34283.1 - 3.5e-07 29.8 0.1 3.5e-06 26.5 0.0 2.0 1 1 0 2 2 2 1 ATPase MipZ AAA_31 PF13614.6 OAG34283.1 - 2.3e-05 24.4 1.1 0.00014 21.8 1.1 2.0 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.15 OAG34283.1 - 7.8e-05 22.0 0.1 0.00014 21.2 0.1 1.4 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_25 PF13481.6 OAG34283.1 - 0.00015 21.4 0.0 0.00025 20.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 OAG34283.1 - 0.00066 18.7 0.1 0.001 18.1 0.1 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_26 PF13500.6 OAG34283.1 - 0.0045 16.8 0.8 0.78 9.5 0.4 2.3 2 0 0 2 2 2 1 AAA domain Desulfoferrod_N PF06397.12 OAG34283.1 - 0.013 15.1 0.7 0.04 13.6 0.7 1.8 1 0 0 1 1 1 0 Desulfoferrodoxin, N-terminal domain CBP_BcsQ PF06564.12 OAG34283.1 - 0.017 14.6 0.1 0.032 13.7 0.1 1.6 1 1 0 1 1 1 0 Cellulose biosynthesis protein BcsQ APS_kinase PF01583.20 OAG34283.1 - 0.026 14.4 0.0 0.04 13.8 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase SRP54 PF00448.22 OAG34283.1 - 0.032 13.8 0.1 1.2 8.7 0.1 2.1 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Zeta_toxin PF06414.12 OAG34283.1 - 0.054 12.8 0.0 0.097 11.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin CLP1_P PF16575.5 OAG34283.1 - 0.074 12.8 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_16 PF13191.6 OAG34283.1 - 0.095 13.1 0.1 0.22 11.9 0.1 1.5 1 0 0 1 1 1 0 AAA ATPase domain IstB_IS21 PF01695.17 OAG34283.1 - 0.16 11.7 0.0 0.34 10.6 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein RsgA_GTPase PF03193.16 OAG34283.1 - 0.26 11.2 0.6 0.65 9.9 0.6 1.6 1 0 0 1 1 1 0 RsgA GTPase Amidohydro_1 PF01979.20 OAG34285.1 - 2.4e-54 185.0 0.0 3e-54 184.6 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 OAG34285.1 - 1e-08 35.1 0.4 1.1e-07 31.7 0.0 2.2 2 0 0 2 2 2 1 Amidohydrolase family A_deaminase PF00962.22 OAG34285.1 - 0.039 13.3 0.0 0.076 12.3 0.0 1.4 1 0 0 1 1 1 0 Adenosine/AMP deaminase SnoaL_4 PF13577.6 OAG34286.1 - 2.4e-22 79.4 2.6 8.4e-20 71.2 2.6 2.2 1 1 0 1 1 1 1 SnoaL-like domain PhetRS_B1 PF18262.1 OAG34286.1 - 0.028 14.6 0.1 0.053 13.7 0.1 1.4 1 0 0 1 1 1 0 Phe-tRNA synthetase beta subunit B1 domain RPE65 PF03055.15 OAG34287.1 - 9.1e-96 321.8 0.0 1.1e-95 321.6 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Aldedh PF00171.22 OAG34288.1 - 4.6e-159 529.8 0.6 5.2e-159 529.6 0.6 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 OAG34288.1 - 0.0036 16.8 0.1 1.3 8.5 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) LuxC PF05893.14 OAG34288.1 - 0.026 13.6 0.1 0.042 12.9 0.1 1.2 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) His_Phos_2 PF00328.22 OAG34290.1 - 4.3e-35 121.8 0.0 5.1e-35 121.5 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) 2-Hacid_dh_C PF02826.19 OAG34291.1 - 2.7e-40 137.6 0.0 4e-40 137.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 OAG34291.1 - 3.9e-19 68.7 0.0 4.7e-19 68.4 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 OAG34291.1 - 0.059 13.5 0.0 0.1 12.8 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase ADH_N_2 PF16884.5 OAG34292.1 - 6e-32 109.8 0.0 1.4e-31 108.6 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 OAG34292.1 - 1.3e-20 73.7 0.0 2.5e-20 72.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAG34292.1 - 3.5e-12 47.5 0.0 7.9e-12 46.4 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase SH3_12 PF18129.1 OAG34292.1 - 0.045 13.9 0.1 11 6.1 0.0 2.6 2 0 0 2 2 2 0 Xrn1 SH3-like domain PXA PF02194.15 OAG34293.1 - 2.6e-48 164.4 0.6 5.1e-48 163.5 0.6 1.5 1 0 0 1 1 1 1 PXA domain Nexin_C PF08628.12 OAG34293.1 - 0.073 13.6 0.0 0.25 11.9 0.0 1.9 1 0 0 1 1 1 0 Sorting nexin C terminal IU_nuc_hydro PF01156.19 OAG34294.1 - 9.6e-32 110.8 0.0 1.2e-31 110.4 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase A_deamin PF02137.18 OAG34295.1 - 4.4e-30 105.3 0.0 8e-30 104.4 0.0 1.4 1 1 0 1 1 1 1 Adenosine-deaminase (editase) domain Fungal_trans PF04082.18 OAG34296.1 - 2e-26 92.6 0.0 4.4e-26 91.5 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG34296.1 - 3.1e-09 36.8 10.6 5.1e-09 36.1 10.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Man-6-P_recep PF02157.15 OAG34297.1 - 6.3e-13 48.4 0.0 8.3e-13 48.0 0.0 1.3 1 1 0 1 1 1 1 Mannose-6-phosphate receptor ATG27 PF09451.10 OAG34297.1 - 3.1e-10 40.3 0.0 6.7e-10 39.3 0.0 1.4 1 1 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.18 OAG34297.1 - 0.0022 18.1 0.0 0.034 14.2 0.0 2.1 2 0 0 2 2 2 1 Cation-independent mannose-6-phosphate receptor repeat ERG4_ERG24 PF01222.17 OAG34298.1 - 8.7e-160 532.2 1.0 1e-159 531.9 1.0 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 OAG34298.1 - 0.0019 17.8 2.1 0.0024 17.4 0.3 2.1 3 0 0 3 3 3 1 Protein of unknown function (DUF1295) MFS_1 PF07690.16 OAG34299.1 - 1.2e-26 93.5 18.8 1.2e-26 93.5 18.8 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 OAG34299.1 - 7.2e-06 24.7 2.0 7.2e-06 24.7 2.0 2.2 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) adh_short PF00106.25 OAG34300.1 - 4.9e-50 169.7 0.2 6.2e-50 169.4 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG34300.1 - 7e-33 114.1 0.0 1e-32 113.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG34300.1 - 4.2e-12 46.3 0.1 6.1e-12 45.8 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG34300.1 - 3.1e-06 26.8 0.0 5.7e-06 26.0 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 OAG34300.1 - 0.0034 17.6 0.1 0.007 16.6 0.1 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain 3Beta_HSD PF01073.19 OAG34300.1 - 0.027 13.5 0.1 0.041 12.9 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 OAG34300.1 - 0.057 12.8 0.0 0.087 12.2 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 OAG34300.1 - 0.092 12.6 0.1 0.16 11.9 0.1 1.4 1 0 0 1 1 1 0 NAD(P)H-binding AMP-binding PF00501.28 OAG34301.1 - 1.9e-72 244.2 0.0 2.4e-72 243.9 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG34301.1 - 3e-11 44.2 0.0 2.8e-10 41.0 0.0 2.6 2 1 1 3 3 3 1 AMP-binding enzyme C-terminal domain CoA_transf_3 PF02515.17 OAG34302.1 - 2.6e-71 240.7 0.0 5.9e-71 239.5 0.0 1.5 1 1 0 1 1 1 1 CoA-transferase family III p450 PF00067.22 OAG34303.1 - 1.1e-71 242.0 0.0 1.3e-71 241.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 OAG34304.1 - 6.7e-71 239.4 0.0 8.9e-71 239.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SUR7 PF06687.12 OAG34305.1 - 7.7e-36 123.7 6.0 9.3e-36 123.4 6.0 1.1 1 0 0 1 1 1 1 SUR7/PalI family CitMHS PF03600.16 OAG34305.1 - 0.028 13.6 0.7 0.037 13.2 0.7 1.2 1 0 0 1 1 1 0 Citrate transporter Amastin PF07344.11 OAG34305.1 - 0.31 10.9 12.1 0.14 12.0 9.6 1.6 2 0 0 2 2 2 0 Amastin surface glycoprotein Rogdi_lz PF10259.9 OAG34306.1 - 8.4e-84 281.2 0.0 9.6e-84 281.0 0.0 1.0 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein AMP-binding PF00501.28 OAG34308.1 - 3e-52 177.7 0.0 4.4e-52 177.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG34308.1 - 0.00039 21.3 0.0 0.00092 20.1 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Thiolase_N PF00108.23 OAG34309.1 - 3.4e-66 223.3 0.2 6.2e-66 222.4 0.1 1.5 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 OAG34309.1 - 3.9e-47 158.9 0.1 7.5e-47 158.0 0.1 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III_C PF08541.10 OAG34309.1 - 0.00026 21.1 0.0 0.00077 19.6 0.0 1.8 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ketoacyl-synt PF00109.26 OAG34309.1 - 0.099 12.2 3.6 0.08 12.5 1.8 1.7 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain Med31 PF05669.12 OAG34310.1 - 1e-29 102.4 0.6 1.4e-29 102.0 0.6 1.1 1 0 0 1 1 1 1 SOH1 Pal1 PF08316.11 OAG34311.1 - 2.7e-49 167.5 0.2 2.7e-49 167.5 0.2 1.9 2 0 0 2 2 2 1 Pal1 cell morphology protein AAA_16 PF13191.6 OAG34314.1 - 8.8e-05 22.9 0.0 0.00025 21.5 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 OAG34314.1 - 0.011 15.3 0.0 0.022 14.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF815 PF05673.13 OAG34314.1 - 0.022 13.9 0.0 0.04 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_29 PF13555.6 OAG34314.1 - 0.18 11.6 0.1 0.36 10.6 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain CLU PF13236.6 OAG34315.1 - 4.2e-75 252.4 0.0 7.4e-75 251.6 0.0 1.4 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 OAG34315.1 - 1.8e-53 181.2 0.0 1.1e-52 178.7 0.0 2.2 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.6 OAG34315.1 - 1e-24 86.6 6.0 1.5e-12 47.6 0.0 4.2 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_10 PF13374.6 OAG34315.1 - 3.6e-24 83.9 0.4 7e-07 28.9 0.0 5.7 5 1 0 5 5 5 3 Tetratricopeptide repeat CLU_N PF15044.6 OAG34315.1 - 5.6e-24 84.3 1.1 1.7e-23 82.8 1.1 1.9 1 0 0 1 1 1 1 Mitochondrial function, CLU-N-term TPR_2 PF07719.17 OAG34315.1 - 2.2e-05 24.2 1.4 10 6.5 0.0 5.7 5 0 0 5 5 5 1 Tetratricopeptide repeat DUF727 PF05303.12 OAG34315.1 - 5.6e-05 23.2 0.0 0.00015 21.8 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF727) TPR_8 PF13181.6 OAG34315.1 - 0.0019 18.3 6.1 0.54 10.6 0.2 4.9 5 1 1 6 6 6 1 Tetratricopeptide repeat BTAD PF03704.17 OAG34315.1 - 0.41 11.1 3.7 3.2 8.2 0.4 3.4 3 1 1 4 4 4 0 Bacterial transcriptional activator domain WD40 PF00400.32 OAG34318.1 - 1.7e-28 98.3 7.7 2.1e-05 25.2 0.2 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat F-box-like PF12937.7 OAG34318.1 - 1.9e-06 27.7 0.4 3.9e-06 26.6 0.4 1.5 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 OAG34318.1 - 2.1e-06 27.9 0.1 0.51 10.7 0.0 4.6 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain F-box PF00646.33 OAG34318.1 - 7.9e-06 25.6 0.1 1.5e-05 24.7 0.1 1.5 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.8 OAG34318.1 - 0.00042 19.1 0.0 0.031 12.9 0.0 2.7 2 1 0 2 2 2 2 Nucleoporin Nup120/160 F-box_4 PF15966.5 OAG34318.1 - 0.0026 17.6 0.0 0.0059 16.5 0.0 1.5 1 0 0 1 1 1 1 F-box Forkhead PF00250.18 OAG34319.1 - 2e-34 117.7 0.7 3.5e-34 116.9 0.7 1.4 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 OAG34319.1 - 3.2e-08 33.8 0.0 6.8e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 FHA domain RRM_1 PF00076.22 OAG34322.1 - 2.8e-12 46.3 0.1 7e-05 22.6 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RanBP PF00641.18 OAG34322.1 - 3.2e-10 39.1 1.2 6.4e-10 38.2 1.2 1.5 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others G-patch PF01585.23 OAG34322.1 - 6.2e-10 38.8 1.1 1.4e-09 37.7 1.1 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 OAG34322.1 - 5.5e-06 26.4 2.3 5.6e-06 26.4 0.1 2.1 2 0 0 2 2 2 1 G-patch domain Rad50_zn_hook PF04423.14 OAG34322.1 - 0.7 9.8 3.8 0.67 9.8 0.2 2.4 2 0 0 2 2 2 0 Rad50 zinc hook motif NCD3G PF07562.14 OAG34322.1 - 5.2 7.1 6.9 11 6.1 1.9 2.3 2 0 0 2 2 2 0 Nine Cysteines Domain of family 3 GPCR Yae1_N PF09811.9 OAG34323.1 - 6.8e-13 48.1 0.3 1.2e-12 47.3 0.3 1.4 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Acatn PF13000.7 OAG34324.1 - 1.4e-154 515.6 17.9 5.6e-81 272.7 9.3 3.1 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 PGA2 PF07543.12 OAG34324.1 - 4.7 7.2 7.0 10 6.1 7.0 1.5 1 0 0 1 1 1 0 Protein trafficking PGA2 ECF_trnsprt PF12822.7 OAG34324.1 - 7.1 6.7 11.7 0.4 10.8 0.3 3.2 2 2 0 2 2 2 0 ECF transporter, substrate-specific component DUF4637 PF15470.6 OAG34324.1 - 7.6 6.2 9.2 18 5.0 9.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) CENP-O PF09496.10 OAG34325.1 - 1.1e-49 169.3 0.0 2.1e-49 168.4 0.0 1.4 1 0 0 1 1 1 1 Cenp-O kinetochore centromere component DUF4611 PF15387.6 OAG34325.1 - 0.32 11.2 4.0 1 9.6 4.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Cwf_Cwc_15 PF04889.12 OAG34325.1 - 0.37 10.5 9.6 1.8 8.3 4.4 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Cyclase PF04199.13 OAG34326.1 - 1.1e-12 48.4 0.0 1.4e-12 48.0 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase adh_short_C2 PF13561.6 OAG34327.1 - 2.8e-64 216.9 2.9 3.1e-64 216.7 2.9 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG34327.1 - 8.7e-50 168.9 0.5 1.2e-49 168.5 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG34327.1 - 1.5e-07 31.5 1.7 2.4e-07 30.8 1.5 1.4 1 1 0 1 1 1 1 KR domain Ldh_1_N PF00056.23 OAG34327.1 - 0.012 15.7 0.2 0.023 14.8 0.2 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Epimerase PF01370.21 OAG34327.1 - 0.031 13.7 0.3 1.6 8.1 0.1 2.2 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Cytochrom_C PF00034.21 OAG34327.1 - 0.081 14.1 0.0 0.17 13.0 0.0 1.7 1 0 0 1 1 1 0 Cytochrome c 3HCDH_N PF02737.18 OAG34327.1 - 0.11 12.4 0.1 0.21 11.4 0.1 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HHH_5 PF14520.6 OAG34327.1 - 0.13 12.9 0.2 0.38 11.4 0.2 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix domain TRI12 PF06609.13 OAG34328.1 - 8e-42 143.4 21.9 1.1e-41 143.0 21.9 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG34328.1 - 4.8e-15 55.4 48.8 1.5e-14 53.7 46.6 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF3087 PF11286.8 OAG34328.1 - 0.45 10.0 4.2 8 5.9 0.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3087) DUF2332 PF10094.9 OAG34329.1 - 0.0033 16.9 0.1 0.0039 16.7 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2332) RNA_pol_Rpc4 PF05132.14 OAG34329.1 - 0.045 14.2 5.3 0.047 14.1 5.3 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF2076 PF09849.9 OAG34329.1 - 0.084 12.9 10.5 0.084 12.9 10.5 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Neur_chan_memb PF02932.16 OAG34329.1 - 0.3 11.1 3.1 0.25 11.4 3.1 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Presenilin PF01080.17 OAG34329.1 - 1.4 7.6 15.6 1.7 7.4 15.6 1.1 1 0 0 1 1 1 0 Presenilin CSG2 PF16965.5 OAG34329.1 - 2.5 6.9 7.5 2.9 6.8 7.5 1.2 1 0 0 1 1 1 0 Ceramide synthase regulator ALMT PF11744.8 OAG34329.1 - 2.8 6.7 12.4 3 6.6 12.4 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter CLN3 PF02487.17 OAG34329.1 - 9.5 5.1 7.5 12 4.8 7.5 1.1 1 0 0 1 1 1 0 CLN3 protein MFS_1 PF07690.16 OAG34330.1 - 0.007 15.3 1.3 0.012 14.5 1.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily AAA PF00004.29 OAG34334.1 - 2e-07 31.5 0.0 6e-07 29.9 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 OAG34334.1 - 0.00022 21.2 0.0 0.00097 19.2 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 OAG34334.1 - 0.0003 21.1 0.0 0.00086 19.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OAG34334.1 - 0.0039 17.6 0.5 0.016 15.6 0.1 2.4 2 1 0 2 2 2 1 AAA ATPase domain ABC_tran PF00005.27 OAG34334.1 - 0.032 14.7 0.0 0.14 12.7 0.0 2.1 2 0 0 2 2 2 0 ABC transporter RsgA_GTPase PF03193.16 OAG34334.1 - 0.046 13.6 0.0 0.16 11.8 0.0 2.1 1 1 0 1 1 1 0 RsgA GTPase AAA_21 PF13304.6 OAG34334.1 - 0.048 13.4 0.0 0.31 10.8 0.0 2.0 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_24 PF13479.6 OAG34334.1 - 0.055 13.2 0.0 0.15 11.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 OAG34334.1 - 0.058 12.5 0.0 0.71 9.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_29 PF13555.6 OAG34334.1 - 0.11 12.2 0.0 0.34 10.7 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activat PF00158.26 OAG34334.1 - 0.11 12.1 0.1 1.9 8.1 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain RNA_helicase PF00910.22 OAG34334.1 - 0.16 12.4 0.0 0.37 11.2 0.0 1.6 1 0 0 1 1 1 0 RNA helicase NB-ARC PF00931.22 OAG34334.1 - 0.16 11.1 0.0 0.4 9.8 0.0 1.6 2 0 0 2 2 2 0 NB-ARC domain EST1_DNA_bind PF10373.9 OAG34336.1 - 0.0024 17.4 0.1 0.0071 15.9 0.0 1.9 2 0 0 2 2 2 1 Est1 DNA/RNA binding domain HET PF06985.11 OAG34340.1 - 2.6e-34 118.7 0.1 7.4e-33 113.9 0.0 2.4 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) AAA PF00004.29 OAG34341.1 - 1.4e-28 100.0 0.0 1.3e-12 48.3 0.0 3.6 4 0 0 4 4 3 2 ATPase family associated with various cellular activities (AAA) AAA_lid_6 PF17866.1 OAG34341.1 - 4e-11 42.9 0.4 5.3e-09 36.1 0.0 3.1 2 0 0 2 2 2 1 AAA lid domain HET PF06985.11 OAG34341.1 - 1.1e-09 38.8 2.2 2.3e-09 37.7 2.2 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) AAA_22 PF13401.6 OAG34341.1 - 2.3e-08 34.4 2.2 0.25 11.6 0.4 4.6 3 1 0 3 3 3 2 AAA domain AAA_30 PF13604.6 OAG34341.1 - 1.4e-06 28.2 0.1 0.064 13.0 0.0 3.2 3 1 0 3 3 3 2 AAA domain AAA_24 PF13479.6 OAG34341.1 - 2.9e-06 27.1 0.0 0.019 14.7 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_18 PF13238.6 OAG34341.1 - 4.9e-06 27.1 0.1 0.14 12.7 0.0 3.2 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.12 OAG34341.1 - 5.3e-06 26.3 0.0 0.11 12.2 0.0 3.3 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 OAG34341.1 - 5.8e-06 25.8 0.0 0.14 11.5 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 OAG34341.1 - 9.1e-06 25.7 1.1 0.26 11.3 0.0 3.6 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 OAG34341.1 - 1.8e-05 24.9 0.0 0.15 12.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 OAG34341.1 - 3.5e-05 24.2 0.0 0.31 11.4 0.0 3.3 3 0 0 3 3 2 2 AAA ATPase domain AAA_17 PF13207.6 OAG34341.1 - 6.2e-05 23.4 1.4 0.62 10.5 0.1 3.6 3 0 0 3 3 3 2 AAA domain TniB PF05621.11 OAG34341.1 - 0.00023 20.7 0.0 3.7 6.9 0.0 3.9 4 0 0 4 4 4 2 Bacterial TniB protein AAA_28 PF13521.6 OAG34341.1 - 0.00035 20.8 0.2 1 9.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 OAG34341.1 - 0.00066 20.0 0.1 4.1 7.7 0.1 3.4 3 0 0 3 3 3 2 AAA domain RNA_helicase PF00910.22 OAG34341.1 - 0.00087 19.7 0.0 2 8.9 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AAA_11 PF13086.6 OAG34341.1 - 0.0021 17.9 0.1 2 8.1 0.0 2.9 3 0 0 3 3 3 2 AAA domain IstB_IS21 PF01695.17 OAG34341.1 - 0.0025 17.6 0.0 2.9 7.6 0.0 2.9 3 0 0 3 3 3 2 IstB-like ATP binding protein NTPase_1 PF03266.15 OAG34341.1 - 0.0045 16.9 0.1 1.9 8.4 0.0 2.5 2 0 0 2 2 2 1 NTPase Viral_helicase1 PF01443.18 OAG34341.1 - 0.011 15.5 0.0 0.41 10.4 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Torsin PF06309.11 OAG34341.1 - 0.029 14.5 0.0 0.87 9.7 0.0 2.7 3 0 0 3 3 2 0 Torsin PhoH PF02562.16 OAG34341.1 - 0.057 12.9 0.1 5 6.5 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein AAA_7 PF12775.7 OAG34341.1 - 0.059 12.9 0.1 15 5.1 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region ABC_tran PF00005.27 OAG34341.1 - 0.19 12.3 0.1 4.8 7.7 0.0 2.7 2 0 0 2 2 2 0 ABC transporter Acetyltransf_3 PF13302.7 OAG34342.1 - 6e-09 36.7 0.0 1.3e-08 35.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GET2 PF08690.10 OAG34342.1 - 0.18 11.5 4.0 0.27 10.9 4.0 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 MFS_1 PF07690.16 OAG34343.1 - 6.2e-27 94.4 34.3 6.2e-27 94.4 34.3 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily FAA_hydrolase PF01557.18 OAG34344.1 - 6.7e-60 202.5 0.0 8.6e-60 202.1 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Fungal_trans PF04082.18 OAG34345.1 - 2.5e-34 118.5 0.1 6.9e-34 117.1 0.1 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG34345.1 - 1.6e-10 40.9 4.5 2.7e-10 40.2 4.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_zinc_N PF00107.26 OAG34346.1 - 5.9e-28 97.4 0.1 8.9e-28 96.9 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG34346.1 - 1.7e-10 40.8 0.5 5e-10 39.2 0.5 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 OAG34346.1 - 7.9e-08 33.4 0.0 1.4e-07 32.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 OAG34346.1 - 0.013 15.0 0.1 0.021 14.3 0.1 1.4 1 0 0 1 1 1 0 short chain dehydrogenase ACP_syn_III_C PF08541.10 OAG34346.1 - 0.06 13.5 0.1 0.15 12.3 0.1 1.6 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal RPN6_C_helix PF18503.1 OAG34346.1 - 0.073 12.8 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 26S proteasome subunit RPN6 C-terminal helix domain MFS_1 PF07690.16 OAG34347.1 - 1.6e-36 126.0 57.6 1.7e-30 106.2 33.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Trp_oprn_chp PF09534.10 OAG34347.1 - 1.2 8.9 3.1 1.1 9.0 0.0 2.4 2 1 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Sld5 PF05916.11 OAG34348.1 - 3.5e-15 56.4 0.0 4.4e-15 56.1 0.0 1.1 1 0 0 1 1 1 1 GINS complex protein Snf7 PF03357.21 OAG34349.1 - 2.7e-46 157.3 15.4 3.2e-46 157.1 15.4 1.0 1 0 0 1 1 1 1 Snf7 CLZ PF16526.5 OAG34349.1 - 0.00024 21.4 4.8 0.0077 16.6 0.0 3.4 2 1 1 3 3 3 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels NPV_P10 PF05531.12 OAG34349.1 - 0.011 16.1 10.0 0.26 11.8 0.1 2.7 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.12 OAG34349.1 - 0.018 15.1 10.4 0.2 11.7 0.2 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) RE_Bsp6I PF09504.10 OAG34349.1 - 0.05 13.2 0.5 0.087 12.4 0.1 1.6 2 0 0 2 2 2 0 Bsp6I restriction endonuclease HHH_2 PF12826.7 OAG34349.1 - 0.052 13.7 0.0 0.097 12.8 0.0 1.4 1 0 0 1 1 1 0 Helix-hairpin-helix motif FlaC_arch PF05377.11 OAG34349.1 - 0.058 13.8 8.4 0.46 10.9 0.2 3.5 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) DUF4201 PF13870.6 OAG34349.1 - 0.072 12.8 12.2 0.21 11.3 9.4 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) End3 PF12761.7 OAG34349.1 - 0.22 11.7 9.2 0.13 12.4 7.5 1.5 1 1 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 FapA PF03961.13 OAG34349.1 - 0.27 9.8 12.5 0.16 10.6 4.4 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A MEIOC PF15189.6 OAG34349.1 - 0.31 10.6 5.8 0.16 11.6 3.4 1.6 1 1 1 2 2 2 0 Meiosis-specific coiled-coil domain-containing protein MEIOC DUF4407 PF14362.6 OAG34349.1 - 0.46 9.8 6.7 0.67 9.2 6.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2205 PF10224.9 OAG34349.1 - 0.61 10.1 6.1 0.41 10.7 1.4 2.7 2 1 0 2 2 2 0 Short coiled-coil protein FliJ PF02050.16 OAG34349.1 - 0.8 9.9 12.8 0.15 12.3 5.5 2.4 1 1 2 3 3 3 0 Flagellar FliJ protein Endotoxin_N PF03945.14 OAG34349.1 - 0.82 9.3 7.2 6.3 6.5 6.9 2.0 1 1 0 1 1 1 0 delta endotoxin, N-terminal domain DUF2120 PF09893.9 OAG34349.1 - 1.1 9.4 5.5 0.69 10.0 3.3 1.8 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) Muted PF14942.6 OAG34349.1 - 1.8 8.9 11.6 14 6.0 8.5 2.2 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein DASH_Dam1 PF08653.10 OAG34349.1 - 3.6 7.5 5.5 24 4.8 0.2 3.3 3 0 0 3 3 3 0 DASH complex subunit Dam1 PEP-utilisers_N PF05524.13 OAG34349.1 - 4.4 7.5 6.7 1.4 9.1 0.9 2.3 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal Atg14 PF10186.9 OAG34349.1 - 5.5 6.0 11.0 13 4.8 11.0 1.6 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 SAPS PF04499.15 OAG34350.1 - 2.3e-194 646.7 0.0 2.3e-194 646.7 0.0 2.5 2 1 0 2 2 2 1 SIT4 phosphatase-associated protein Lyase_1 PF00206.20 OAG34351.1 - 6.4e-91 305.0 0.0 9.9e-91 304.4 0.0 1.3 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 OAG34351.1 - 8.7e-22 77.7 0.2 2.5e-21 76.2 0.2 1.8 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal IL28A PF15177.6 OAG34351.1 - 0.045 13.6 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 Interleukin-28A HET PF06985.11 OAG34352.1 - 3e-26 92.5 0.0 5.8e-26 91.6 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) AMP-binding PF00501.28 OAG34353.1 - 1.3e-41 142.6 0.0 1.9e-41 142.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 OAG34353.1 - 0.0017 18.2 1.2 0.0026 17.6 0.1 1.9 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 OAG34353.1 - 0.085 13.8 0.0 0.2 12.7 0.0 1.6 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain NICE-1 PF15845.5 OAG34354.1 - 0.02 15.7 0.2 0.042 14.6 0.2 1.5 1 0 0 1 1 1 0 Cysteine-rich C-terminal 1 family GPI-anchored PF10342.9 OAG34354.1 - 0.026 15.3 0.4 0.052 14.3 0.4 1.6 1 0 0 1 1 1 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Abhydrolase_1 PF00561.20 OAG34355.1 - 7e-11 42.3 0.0 1.3e-10 41.4 0.0 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG34355.1 - 8.7e-08 33.0 0.6 1e-07 32.8 0.6 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.14 OAG34355.1 - 0.0063 15.2 0.0 0.0085 14.8 0.0 1.1 1 0 0 1 1 1 1 Ndr family Hydrolase_4 PF12146.8 OAG34355.1 - 0.014 14.7 0.0 0.018 14.3 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 FAD_binding_4 PF01565.23 OAG34357.1 - 3.6e-17 62.4 0.0 6.7e-17 61.5 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 OAG34357.1 - 6.6e-07 29.3 0.8 3.3e-05 23.9 0.6 2.5 2 0 0 2 2 2 1 Berberine and berberine like Cytokin-bind PF09265.10 OAG34357.1 - 0.024 14.0 0.0 0.041 13.3 0.0 1.3 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding Lactamase_B PF00753.27 OAG34358.1 - 9.9e-06 25.7 0.4 4.5e-05 23.6 0.2 2.0 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OAG34358.1 - 0.0081 15.7 0.6 0.015 14.8 0.6 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain SnoaL_2 PF12680.7 OAG34359.1 - 0.0021 18.7 0.0 0.003 18.2 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain TLP-20 PF06088.11 OAG34359.1 - 0.03 14.2 0.0 0.039 13.8 0.0 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Fungal_trans_2 PF11951.8 OAG34360.1 - 5.4e-06 25.5 0.1 9.9e-06 24.6 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG34360.1 - 0.011 15.8 2.8 0.019 15.1 2.8 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Med5 PF08689.10 OAG34361.1 - 3.4e-40 137.8 1.9 1.8e-38 132.1 0.0 2.9 3 0 0 3 3 3 3 Mediator complex subunit Med5 MutL_C PF08676.11 OAG34362.1 - 6.1e-12 45.5 0.0 4.9e-11 42.6 0.0 2.1 2 0 0 2 2 2 1 MutL C terminal dimerisation domain HATPase_c_3 PF13589.6 OAG34362.1 - 1.5e-10 41.0 0.0 5.2e-10 39.3 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 OAG34362.1 - 0.027 15.0 0.0 0.074 13.6 0.0 1.8 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Hexapep PF00132.24 OAG34363.1 - 1.9e-08 33.7 9.0 2.7e-05 23.7 1.2 3.2 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Zn_clus PF00172.18 OAG34363.1 - 2.6e-08 33.8 9.0 5.3e-08 32.9 9.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mac PF12464.8 OAG34363.1 - 4.6e-05 23.6 0.2 0.00013 22.2 0.2 1.7 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep_2 PF14602.6 OAG34363.1 - 0.00014 21.6 5.7 0.0015 18.2 0.5 2.6 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase TPR_11 PF13414.6 OAG34363.1 - 0.079 12.7 0.2 0.14 11.8 0.2 1.4 1 0 0 1 1 1 0 TPR repeat RasGEF PF00617.19 OAG34364.1 - 2.7e-50 171.0 0.5 5.2e-50 170.1 0.5 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 OAG34364.1 - 2.1e-12 47.2 0.0 1.3e-11 44.7 0.0 2.4 2 0 0 2 2 2 1 RasGEF N-terminal motif SH3_9 PF14604.6 OAG34364.1 - 6.3e-08 32.4 0.0 1.4e-07 31.2 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 OAG34364.1 - 5e-06 26.0 0.0 1.2e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 SH3 domain I_LWEQ PF01608.17 OAG34364.1 - 0.078 13.2 0.9 0.72 10.1 0.4 2.6 2 1 0 2 2 2 0 I/LWEQ domain zf-RING_2 PF13639.6 OAG34365.1 - 2.7e-07 30.8 9.6 2.7e-07 30.8 9.6 1.9 2 0 0 2 2 2 1 Ring finger domain zf-ANAPC11 PF12861.7 OAG34365.1 - 0.00011 22.2 4.9 0.00011 22.2 4.9 1.7 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 OAG34365.1 - 0.0016 18.2 10.2 0.0037 17.0 10.2 1.7 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.6 OAG34365.1 - 0.0027 17.7 8.9 0.0065 16.5 8.9 1.7 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_1 PF14446.6 OAG34365.1 - 0.003 17.5 11.6 0.013 15.4 11.5 2.1 1 1 1 2 2 2 1 Prokaryotic RING finger family 1 zf-RING_5 PF14634.6 OAG34365.1 - 0.024 14.6 10.2 0.059 13.3 10.2 1.7 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_3 PF13920.6 OAG34365.1 - 0.039 13.8 8.8 0.12 12.2 8.7 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 OAG34365.1 - 0.17 11.6 10.8 0.38 10.4 10.8 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 OAG34365.1 - 0.62 10.3 15.5 0.095 12.9 10.6 2.3 2 1 0 2 2 1 0 FANCL C-terminal domain IBR PF01485.21 OAG34365.1 - 1.6 9.0 10.6 2.2 8.6 9.3 1.9 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain zf-C3HC4_2 PF13923.6 OAG34365.1 - 2.6 8.0 16.6 0.15 11.9 9.5 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OAG34365.1 - 2.8 8.2 9.6 19 5.5 9.6 2.2 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 OAG34365.1 - 3 8.2 16.8 0.17 12.2 10.8 2.1 2 1 0 2 2 2 0 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 OAG34365.1 - 3.1 7.7 9.6 17 5.4 0.1 2.8 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 OAG34365.1 - 4.3 7.2 9.2 1.5 8.6 6.4 1.8 2 0 0 2 2 1 0 RING-like zinc finger Cation_efflux PF01545.21 OAG34366.1 - 3.8e-23 82.3 5.6 5e-23 81.9 5.6 1.2 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 OAG34366.1 - 0.00098 19.2 0.0 0.0023 18.0 0.0 1.6 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter AA_permease_2 PF13520.6 OAG34367.1 - 2.4e-56 191.4 50.7 2.8e-56 191.2 50.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAG34367.1 - 1.4e-19 70.1 40.1 1.9e-19 69.7 40.1 1.1 1 0 0 1 1 1 1 Amino acid permease PDR_CDR PF06422.12 OAG34367.1 - 1 9.3 3.9 1.5 8.8 0.1 3.1 3 0 0 3 3 3 0 CDR ABC transporter TadE PF07811.12 OAG34367.1 - 5.3 7.4 9.3 7.4 6.9 1.0 3.9 3 0 0 3 3 3 0 TadE-like protein Methyltransf_4 PF02390.17 OAG34368.1 - 1.5e-45 154.8 0.0 2.3e-45 154.1 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 OAG34368.1 - 0.051 14.3 0.1 0.12 13.0 0.1 1.9 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.6 OAG34368.1 - 0.1 12.5 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain RNB PF00773.19 OAG34369.1 - 1.1e-96 324.0 0.1 1.7e-96 323.4 0.1 1.2 1 0 0 1 1 1 1 RNB domain Rrp44_CSD1 PF17216.3 OAG34369.1 - 6.5e-34 116.8 0.0 1.5e-33 115.6 0.0 1.6 1 0 0 1 1 1 1 Rrp44-like cold shock domain Rrp44_S1 PF17215.3 OAG34369.1 - 7.6e-26 89.9 0.8 1.6e-25 88.9 0.8 1.6 1 0 0 1 1 1 1 S1 domain OB_Dis3 PF17849.1 OAG34369.1 - 5.7e-22 77.5 0.0 1.4e-21 76.3 0.0 1.7 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) PIN_4 PF13638.6 OAG34369.1 - 3.1e-13 50.1 0.5 7.5e-13 48.9 0.5 1.7 1 0 0 1 1 1 1 PIN domain CSD2 PF17876.1 OAG34369.1 - 3.9e-06 26.9 0.0 0.00027 21.0 0.0 3.0 2 0 0 2 2 2 1 Cold shock domain PIN_9 PF18477.1 OAG34369.1 - 0.069 13.5 3.1 0.64 10.4 0.2 3.0 3 0 0 3 3 3 0 PIN like domain Dis3l2_C_term PF17877.1 OAG34369.1 - 0.093 13.1 0.1 0.3 11.4 0.1 1.9 1 0 0 1 1 1 0 DIS3-like exonuclease 2 C terminal Abhydrolase_2 PF02230.16 OAG34370.1 - 5.8e-35 121.1 0.0 5.7e-34 117.8 0.0 2.0 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase FSH1 PF03959.13 OAG34370.1 - 3.5e-05 23.6 0.0 6.5e-05 22.7 0.0 1.4 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 OAG34370.1 - 0.0025 18.4 0.0 0.009 16.6 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAG34370.1 - 0.01 15.5 0.0 0.051 13.2 0.0 1.9 1 1 1 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 OAG34370.1 - 0.016 15.1 0.0 0.048 13.5 0.0 1.7 1 1 1 2 2 2 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAG34370.1 - 0.016 14.5 0.0 2.5 7.3 0.0 2.4 2 1 1 3 3 3 0 Serine aminopeptidase, S33 AXE1 PF05448.12 OAG34370.1 - 0.028 13.1 0.0 0.053 12.2 0.0 1.4 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Cutinase PF01083.22 OAG34370.1 - 0.073 13.0 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Cutinase SSF PF00474.17 OAG34371.1 - 1.5e-10 40.6 18.5 9.4e-08 31.3 4.5 2.3 2 0 0 2 2 2 2 Sodium:solute symporter family Peptidase_M20 PF01546.28 OAG34372.1 - 7.2e-20 71.6 0.1 1.1e-19 71.0 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 OAG34372.1 - 0.00059 19.7 0.0 0.0012 18.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 OAG34372.1 - 0.082 12.6 0.0 0.22 11.2 0.0 1.6 1 1 0 1 1 1 0 Peptidase family M28 Bap31_Bap29_C PF18035.1 OAG34373.1 - 0.04 13.9 1.0 0.068 13.2 1.0 1.4 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain Histone PF00125.24 OAG34377.1 - 3.5e-38 130.9 1.8 3.8e-38 130.8 1.8 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 OAG34377.1 - 5.6e-08 32.9 0.0 7.7e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Bromo_TP PF07524.13 OAG34377.1 - 0.00054 19.9 0.1 0.00078 19.4 0.1 1.2 1 0 0 1 1 1 1 Bromodomain associated CENP-S PF15630.6 OAG34377.1 - 0.0006 20.1 0.0 0.00093 19.5 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 OAG34377.1 - 0.0012 19.1 0.0 0.0018 18.5 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 OAG34377.1 - 0.043 13.9 0.0 0.056 13.5 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit DUF5387 PF17361.2 OAG34379.1 - 0.047 13.4 1.7 2.3 7.9 0.1 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5387) RT_RNaseH PF17917.1 OAG34381.1 - 7e-25 87.3 0.1 1.5e-24 86.3 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 OAG34381.1 - 2.3e-12 46.8 0.0 6.1e-12 45.5 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Chromo PF00385.24 OAG34381.1 - 1.9e-07 30.8 0.0 5.5e-07 29.4 0.0 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Integrase_H2C2 PF17921.1 OAG34381.1 - 1e-06 28.8 0.1 1.8e-06 27.9 0.1 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain DUF2202 PF09968.9 OAG34381.1 - 0.018 14.9 0.1 0.031 14.1 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein domain (DUF2202) ATP-synt_DE PF00401.20 OAG34381.1 - 3 8.2 11.6 0.25 11.6 2.5 2.7 2 0 0 2 2 2 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain MATalpha_HMGbox PF04769.12 OAG34384.1 - 1.4e-36 125.7 0.0 1.8e-36 125.3 0.0 1.1 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 HMG-box DinB PF05163.12 OAG34386.1 - 0.31 11.0 2.4 0.28 11.1 0.4 1.8 2 0 0 2 2 2 0 DinB family zf-CCHC PF00098.23 OAG34386.1 - 1.9 8.7 9.8 1.2 9.3 1.1 2.4 2 0 0 2 2 2 0 Zinc knuckle Macro PF01661.21 OAG34387.1 - 2.3e-21 76.0 0.2 3.2e-21 75.6 0.2 1.2 1 0 0 1 1 1 1 Macro domain RRM_1 PF00076.22 OAG34388.1 - 2.6e-37 126.4 0.0 1.2e-17 63.5 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OAG34388.1 - 0.00025 21.1 0.0 0.027 14.6 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif RRM_5 PF13893.6 OAG34388.1 - 0.00032 20.3 0.0 0.016 14.8 0.0 2.2 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 OAG34388.1 - 0.012 15.9 0.1 0.38 11.0 0.0 2.2 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter OB_RNB PF08206.11 OAG34388.1 - 0.012 15.3 0.1 6.2 6.6 0.0 2.5 2 0 0 2 2 2 0 Ribonuclease B OB domain Limkain-b1 PF11608.8 OAG34388.1 - 0.036 14.1 0.4 1.2 9.3 0.1 2.2 2 0 0 2 2 2 0 Limkain b1 RRM_occluded PF16842.5 OAG34388.1 - 0.045 13.6 0.0 0.081 12.8 0.0 1.4 1 0 0 1 1 1 0 Occluded RNA-recognition motif WD40 PF00400.32 OAG34389.1 - 2.8e-60 198.8 9.9 5.9e-09 36.4 0.1 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG34389.1 - 2.5e-18 66.2 0.0 2.9e-06 27.5 0.0 6.4 1 1 6 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Tup_N PF08581.10 OAG34389.1 - 1.3e-16 60.7 11.8 2.3e-16 59.9 11.8 1.4 1 0 0 1 1 1 1 Tup N-terminal WD40_like PF17005.5 OAG34389.1 - 2.2e-08 33.8 0.0 0.0026 17.2 0.0 4.8 3 1 2 5 5 5 1 WD40-like domain Ge1_WD40 PF16529.5 OAG34389.1 - 1.5e-06 27.4 0.1 1.6 7.6 0.0 4.7 1 1 4 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 OAG34389.1 - 2.7e-05 23.6 0.1 0.044 13.1 0.0 2.9 2 1 1 3 3 3 2 Neuroblastoma-amplified sequence, N terminal eIF2A PF08662.11 OAG34389.1 - 0.00049 20.0 0.0 0.073 12.9 0.0 3.1 1 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Peptidase_S9_N PF02897.15 OAG34389.1 - 0.00051 19.0 0.0 0.023 13.5 0.0 2.9 2 1 0 2 2 2 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Nup160 PF11715.8 OAG34389.1 - 0.0028 16.4 0.1 6 5.4 0.0 3.3 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 OAG34389.1 - 0.0055 15.3 0.3 0.022 13.3 0.2 2.0 1 1 1 2 2 2 1 Cytochrome D1 heme domain Nucleoporin_N PF08801.11 OAG34389.1 - 0.015 14.1 0.2 6.9 5.3 0.1 3.8 2 1 2 4 4 4 0 Nup133 N terminal like Golgin_A5 PF09787.9 OAG34389.1 - 1 8.7 8.8 1.5 8.2 8.8 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 Proteasome_A_N PF10584.9 OAG34389.1 - 2.9 7.6 7.0 7.6 6.3 0.0 4.4 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature zf-C2H2 PF00096.26 OAG34390.1 - 1.8e-12 47.0 16.3 0.00082 19.7 3.4 4.0 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OAG34390.1 - 1.8e-06 28.1 1.3 1.8e-06 28.1 1.3 4.8 4 1 0 4 4 4 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 OAG34390.1 - 2.8e-06 27.7 14.4 0.075 13.9 0.5 4.0 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_8 PF15909.5 OAG34390.1 - 0.0048 17.2 1.7 0.019 15.3 1.1 2.3 1 1 1 2 2 2 1 C2H2-type zinc ribbon FOXP-CC PF16159.5 OAG34390.1 - 0.14 12.8 4.9 0.82 10.3 1.1 3.1 2 1 0 2 2 2 0 FOXP coiled-coil domain zf-met PF12874.7 OAG34390.1 - 0.18 12.2 1.4 9.7 6.7 0.4 3.4 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Mito_carr PF00153.27 OAG34391.1 - 4.3e-64 212.5 0.2 2.3e-20 72.3 0.3 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein NiFe_hyd_3_EhaA PF17367.2 OAG34391.1 - 0.11 12.7 1.1 0.14 12.3 0.1 1.7 2 0 0 2 2 2 0 NiFe-hydrogenase-type-3 Eha complex subunit A FA_hydroxylase PF04116.13 OAG34392.1 - 1.2e-24 87.2 18.8 1.6e-24 86.8 15.2 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF2015 PF09435.10 OAG34393.1 - 3.5e-43 146.0 0.0 4.2e-43 145.8 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) Ribosomal_L28e PF01778.17 OAG34394.1 - 2.9e-35 121.5 1.8 3.7e-35 121.2 1.8 1.1 1 0 0 1 1 1 1 Ribosomal L28e protein family Ldh_1_C PF02866.18 OAG34395.1 - 6.4e-45 153.1 0.0 1.1e-44 152.3 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 OAG34395.1 - 1.5e-40 138.6 0.1 1.2e-39 135.7 0.1 2.0 1 1 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 OAG34395.1 - 0.016 14.2 0.0 0.038 13.0 0.0 1.6 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family TRAPP PF04051.16 OAG34396.1 - 1.8e-37 128.3 0.0 2.3e-37 127.9 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component SSP160 PF06933.11 OAG34396.1 - 5.9 5.0 15.3 7.3 4.7 15.3 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Sec16_C PF12931.7 OAG34397.1 - 1.9e-107 359.4 0.0 2.6e-107 359.0 0.0 1.2 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.7 OAG34397.1 - 7.3e-31 107.2 0.0 1.9e-30 105.8 0.0 1.8 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region DUF1952 PF09189.10 OAG34397.1 - 0.15 12.0 0.0 0.35 10.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1952) PhoLip_ATPase_C PF16212.5 OAG34398.1 - 3.4e-51 174.4 3.7 3.4e-51 174.4 3.7 2.6 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 OAG34398.1 - 9.2e-17 60.5 1.9 1.8e-16 59.5 1.9 1.4 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 OAG34398.1 - 5e-13 49.8 6.1 4.8e-07 30.3 3.7 3.9 3 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase Mso1_Sec1_bdg PF14475.6 OAG34398.1 - 5.6e-12 45.0 0.1 1.6e-11 43.6 0.1 1.8 1 0 0 1 1 1 1 Sec1-binding region of Mso1 E1-E2_ATPase PF00122.20 OAG34398.1 - 8.1e-07 28.7 2.1 8.8e-06 25.4 2.1 2.3 1 1 0 1 1 1 1 E1-E2 ATPase Cation_ATPase PF13246.6 OAG34398.1 - 1.9e-05 24.7 0.0 0.00018 21.6 0.0 2.5 2 1 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 OAG34398.1 - 0.0053 16.5 0.0 0.0095 15.7 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase AMP_N PF05195.16 OAG34399.1 - 0.019 14.7 0.1 0.038 13.7 0.1 1.5 1 0 0 1 1 1 0 Aminopeptidase P, N-terminal domain DUF892 PF05974.12 OAG34399.1 - 0.058 13.4 0.0 0.13 12.2 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF892) YIF1 PF03878.15 OAG34400.1 - 1.1e-98 329.6 7.1 1.2e-98 329.4 7.1 1.0 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.17 OAG34400.1 - 0.00044 20.0 8.8 0.00044 20.0 8.8 1.9 2 0 0 2 2 2 1 Yip1 domain MFS_1 PF07690.16 OAG34401.1 - 2.2e-35 122.3 29.1 2.7e-35 121.9 29.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4131 PF13567.6 OAG34401.1 - 3 7.5 9.9 14 5.3 0.4 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) adh_short PF00106.25 OAG34402.1 - 9.5e-23 80.7 0.0 5.2e-11 42.4 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAG34402.1 - 3.9e-16 59.3 0.0 5e-07 29.5 0.0 2.2 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short_C2 PF13561.6 OAG34404.1 - 6.3e-40 137.2 1.1 9.6e-40 136.6 1.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG34404.1 - 2e-34 118.8 1.0 3e-34 118.2 1.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase HET PF06985.11 OAG34404.1 - 7.8e-31 107.4 0.1 1.4e-30 106.6 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) KR PF08659.10 OAG34404.1 - 5.2e-12 46.1 0.5 8.6e-12 45.3 0.5 1.3 1 0 0 1 1 1 1 KR domain Abhydrolase_6 PF12697.7 OAG34405.1 - 1.7e-21 77.8 0.1 2e-21 77.7 0.1 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 OAG34405.1 - 0.0074 16.0 0.3 0.025 14.3 0.1 1.9 2 1 0 2 2 2 1 PGAP1-like protein ANAPC10 PF03256.16 OAG34405.1 - 0.051 13.2 0.0 0.082 12.5 0.0 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex, subunit 10 (APC10) zf-C3HC4_3 PF13920.6 OAG34406.1 - 3.7e-10 39.5 14.1 6.1e-10 38.8 14.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) UCH PF00443.29 OAG34406.1 - 2.6e-06 27.1 0.0 4.7e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg PF12436.8 OAG34406.1 - 3.5e-06 26.5 0.0 0.0029 17.0 0.0 2.5 2 0 0 2 2 2 2 ICP0-binding domain of Ubiquitin-specific protease 7 MORN PF02493.20 OAG34406.1 - 0.00099 18.9 21.5 0.0023 17.7 1.9 4.6 4 0 0 4 4 4 2 MORN repeat Prok-RING_4 PF14447.6 OAG34406.1 - 0.12 12.3 13.6 0.23 11.3 13.6 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 DS PF01916.17 OAG34407.1 - 8.1e-122 406.0 0.0 9.3e-122 405.8 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase Myb_DNA-binding PF00249.31 OAG34408.1 - 3.4e-10 39.9 0.0 2.7e-06 27.5 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OAG34408.1 - 0.0087 16.3 0.0 0.13 12.5 0.1 2.5 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OAG34408.1 - 0.014 15.3 0.0 0.014 15.3 0.0 2.4 3 0 0 3 3 3 0 Myb DNA-binding like Asp_decarbox PF02261.16 OAG34408.1 - 0.14 12.1 1.9 0.28 11.1 1.9 1.4 1 0 0 1 1 1 0 Aspartate decarboxylase MINDY_DUB PF04424.13 OAG34409.1 - 5.7e-22 77.9 0.0 9.9e-22 77.2 0.0 1.3 1 0 0 1 1 1 1 MINDY deubiquitinase DUF3669 PF12417.8 OAG34410.1 - 9.3e-11 41.8 0.0 3.2e-10 40.1 0.0 2.0 1 0 0 1 1 1 1 Zinc finger protein CobT PF06213.12 OAG34410.1 - 4 6.8 9.7 5.5 6.3 9.7 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT adh_short PF00106.25 OAG34411.1 - 9.1e-27 93.8 0.4 1.8e-20 73.2 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAG34411.1 - 1.1e-15 57.9 0.6 5e-14 52.4 0.1 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG34411.1 - 8.5e-07 29.0 0.1 1.3e-06 28.5 0.1 1.3 1 0 0 1 1 1 1 KR domain DUF3073 PF11273.8 OAG34411.1 - 0.076 13.8 0.0 0.15 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3073) Iso_dh PF00180.20 OAG34413.1 - 4.8e-107 358.1 0.0 5.4e-107 357.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Gloverin PF10793.9 OAG34413.1 - 0.051 13.5 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Gloverin-like protein EF-hand_1 PF00036.32 OAG34414.1 - 2.2e-26 89.4 15.9 5e-08 31.9 0.3 4.7 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.6 OAG34414.1 - 3.9e-23 81.7 12.9 2.1e-14 53.7 1.0 2.8 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 OAG34414.1 - 3.2e-19 67.1 10.7 0.00011 21.8 0.1 5.0 5 0 0 5 5 5 4 EF-hand domain EF-hand_5 PF13202.6 OAG34414.1 - 1.6e-17 62.1 13.2 1.8e-06 27.2 0.3 4.7 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.6 OAG34414.1 - 1.1e-10 41.2 13.6 0.00083 19.2 0.3 4.5 3 1 2 5 5 5 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 OAG34414.1 - 2.6e-06 27.7 0.1 0.011 16.1 0.0 2.4 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 OAG34414.1 - 4.9e-05 23.2 8.6 0.1 12.6 0.2 4.0 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 OAG34414.1 - 0.081 13.1 0.5 0.29 11.4 0.4 2.0 1 1 0 1 1 1 0 Dockerin type I domain EPL1 PF10513.9 OAG34415.1 - 5.9e-23 82.0 0.2 5.9e-23 82.0 0.2 2.2 2 1 0 2 2 2 1 Enhancer of polycomb-like DUF2188 PF09954.9 OAG34415.1 - 0.066 13.4 0.4 0.19 11.9 0.4 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2188) SET PF00856.28 OAG34416.1 - 2.6e-18 67.0 0.0 4.7e-18 66.2 0.0 1.4 1 0 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.11 OAG34416.1 - 3.6e-07 30.9 0.1 1.8e-06 28.7 0.0 2.3 2 0 0 2 2 2 1 Rubisco LSMT substrate-binding Peptidase_M22 PF00814.25 OAG34417.1 - 4e-87 292.4 0.0 4.7e-87 292.1 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.15 OAG34417.1 - 0.11 12.2 0.0 1.3 8.6 0.0 2.1 2 0 0 2 2 2 0 Carbamoyltransferase N-terminus AMPK1_CBM PF16561.5 OAG34418.1 - 4e-29 100.7 0.2 6.7e-29 100.0 0.2 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase AMPKBI PF04739.15 OAG34418.1 - 9.8e-23 80.2 2.8 1.1e-22 80.1 0.6 2.3 2 0 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interaction domain CBM53 PF16760.5 OAG34418.1 - 0.09 13.4 0.1 0.2 12.2 0.1 1.6 1 0 0 1 1 1 0 Starch/carbohydrate-binding module (family 53) TYA PF01021.19 OAG34418.1 - 2.6 8.4 7.1 1.4 9.3 0.5 2.7 2 0 0 2 2 2 0 TYA transposon protein DUF2070 PF09843.9 OAG34419.1 - 9.7 4.3 9.2 13 3.9 9.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) RRM_2 PF04059.12 OAG34420.1 - 6.9e-32 109.5 0.1 1.3e-31 108.6 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.22 OAG34420.1 - 0.0016 18.2 0.0 0.24 11.2 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sec15 PF04091.12 OAG34421.1 - 2e-101 339.6 1.0 2e-101 339.6 1.0 2.7 3 1 1 4 4 4 1 Exocyst complex subunit Sec15-like COG2 PF06148.11 OAG34421.1 - 3.1e-05 24.1 5.7 0.00018 21.6 4.2 2.8 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF2451 PF10474.9 OAG34421.1 - 8.8e-05 22.4 0.0 0.00039 20.3 0.0 2.1 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) AAA_5 PF07728.14 OAG34421.1 - 0.0073 16.3 0.9 0.018 15.0 0.9 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) COG5 PF10392.9 OAG34421.1 - 0.012 15.7 4.7 0.012 15.7 4.7 3.1 3 0 0 3 3 3 0 Golgi transport complex subunit 5 Phage_holin_6_1 PF09682.10 OAG34421.1 - 0.023 15.1 0.2 0.08 13.4 0.2 2.0 1 0 0 1 1 1 0 Bacteriophage holin of superfamily 6 (Holin_LLH) Vps51 PF08700.11 OAG34421.1 - 0.042 13.9 0.5 0.25 11.4 0.5 2.5 1 0 0 1 1 1 0 Vps51/Vps67 Prominin PF05478.11 OAG34421.1 - 0.051 11.5 12.2 0.0084 14.1 7.6 1.9 2 0 0 2 2 2 0 Prominin DUF3510 PF12022.8 OAG34421.1 - 0.064 13.6 4.0 3 8.3 0.0 4.0 4 1 1 5 5 5 0 Domain of unknown function (DUF3510) Sec8_exocyst PF04048.14 OAG34421.1 - 0.083 12.8 8.6 0.041 13.8 4.2 2.7 2 1 1 3 3 3 0 Sec8 exocyst complex component specific domain ApoLp-III PF07464.11 OAG34421.1 - 0.33 11.1 6.1 0.075 13.1 2.0 2.1 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) YkyA PF10368.9 OAG34421.1 - 1 9.0 6.9 3.1 7.4 6.9 1.8 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein zf-RING_9 PF13901.6 OAG34421.1 - 3.2 7.7 6.0 5.9 6.8 2.1 2.8 3 0 0 3 3 3 0 Putative zinc-RING and/or ribbon CBFD_NFYB_HMF PF00808.23 OAG34422.1 - 9.2e-19 67.5 0.6 1.3e-18 67.0 0.6 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 OAG34422.1 - 6.3e-16 58.9 0.8 7.7e-16 58.7 0.1 1.5 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.10 OAG34422.1 - 0.06 13.7 0.0 0.097 13.0 0.0 1.3 1 0 0 1 1 1 0 CENP-S associating Centromere protein X Mucin-like PF16058.5 OAG34422.1 - 0.51 10.4 15.3 2.4 8.3 15.3 2.2 1 1 0 1 1 1 0 Mucin-like Mpv17_PMP22 PF04117.12 OAG34423.1 - 7e-21 74.2 6.9 8.9e-20 70.7 0.6 2.7 3 0 0 3 3 3 2 Mpv17 / PMP22 family Vps4_C PF09336.10 OAG34424.1 - 0.069 13.2 0.2 0.51 10.4 0.1 2.3 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain Fcf2 PF08698.11 OAG34425.1 - 8.6e-35 119.0 0.5 8.6e-35 119.0 0.5 1.9 2 0 0 2 2 2 1 Fcf2 pre-rRNA processing CAS_CSE1 PF03378.15 OAG34427.1 - 2.1e-173 576.9 0.0 7.5e-173 575.1 0.0 1.9 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus Cse1 PF08506.10 OAG34427.1 - 7.7e-151 502.1 0.6 1.1e-150 501.6 0.6 1.2 1 0 0 1 1 1 1 Cse1 IBN_N PF03810.19 OAG34427.1 - 2.1e-15 56.4 0.0 1.1e-14 54.1 0.0 2.3 1 0 0 1 1 1 1 Importin-beta N-terminal domain Phyto_Pns9_10 PF05878.11 OAG34427.1 - 0.012 14.8 0.0 0.022 14.0 0.0 1.3 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns9/Pns10 Xpo1 PF08389.12 OAG34427.1 - 0.041 13.9 1.1 0.31 11.1 0.0 3.2 4 0 0 4 4 4 0 Exportin 1-like protein Rap_GAP PF02145.15 OAG34428.1 - 4.5e-39 133.9 0.0 7.4e-39 133.2 0.0 1.3 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.16 OAG34428.1 - 2.5e-25 89.3 2.9 1.4e-22 80.3 0.2 3.7 4 0 0 4 4 4 3 Tuberin DUF3384 PF11864.8 OAG34428.1 - 3.2e-24 85.7 0.0 6.6e-24 84.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3384) RabGAP-TBC PF00566.18 OAG34429.1 - 1.3e-32 113.3 5.7 1.9e-30 106.2 4.2 2.4 2 0 0 2 2 2 2 Rab-GTPase-TBC domain PH_RBD PF12068.8 OAG34429.1 - 1.5e-09 37.6 0.0 4.2e-08 32.8 0.0 2.8 2 1 0 2 2 2 1 Rab-binding domain (RBD) Peptidase_M60 PF13402.6 OAG34429.1 - 0.035 13.6 0.1 0.068 12.7 0.1 1.5 1 0 0 1 1 1 0 Peptidase M60, enhancin and enhancin-like TBCC_N PF16752.5 OAG34429.1 - 0.2 12.1 1.8 0.62 10.5 1.8 1.9 1 0 0 1 1 1 0 Tubulin-specific chaperone C N-terminal domain RF-1 PF00472.20 OAG34431.1 - 3.5e-24 85.0 3.9 5.2e-24 84.4 3.9 1.2 1 0 0 1 1 1 1 RF-1 domain DUF2726 PF10881.8 OAG34431.1 - 0.0063 16.4 0.9 0.0092 15.9 0.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2726) PBP_sp32 PF07222.12 OAG34431.1 - 0.41 10.1 3.8 0.57 9.6 3.8 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 adh_short_C2 PF13561.6 OAG34432.1 - 9e-52 176.0 0.0 2.2e-48 164.9 0.0 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG34432.1 - 4.4e-46 156.8 0.0 2.2e-37 128.4 0.0 2.0 1 1 1 2 2 2 2 short chain dehydrogenase KR PF08659.10 OAG34432.1 - 0.00019 21.4 0.0 0.0003 20.8 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG34432.1 - 0.011 15.2 0.2 0.047 13.1 0.2 2.2 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family HA2 PF04408.23 OAG34433.1 - 5.7e-16 58.8 0.1 5.7e-16 58.8 0.1 2.4 2 1 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 OAG34433.1 - 3.1e-14 53.3 0.4 1.2e-13 51.3 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 OAG34433.1 - 3.9e-11 43.0 0.1 9.3e-11 41.8 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.16 OAG34433.1 - 0.00056 20.2 0.0 0.0013 19.0 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.6 OAG34433.1 - 0.027 14.8 0.6 0.084 13.2 0.1 2.1 2 0 0 2 2 2 0 AAA domain Pacs-1 PF10254.9 OAG34433.1 - 8.4 5.2 6.7 16 4.3 6.7 1.4 1 0 0 1 1 1 0 PACS-1 cytosolic sorting protein HET PF06985.11 OAG34434.1 - 3.4e-29 102.1 0.0 7.2e-29 101.0 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF866 PF05907.13 OAG34435.1 - 9.4e-46 155.5 1.3 1e-45 155.4 1.3 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) DUF4379 PF14311.6 OAG34435.1 - 0.094 13.1 3.0 0.14 12.6 1.6 2.1 2 1 0 2 2 2 0 Probable Zinc-ribbon domain ABC_transp_aux PF09822.9 OAG34436.1 - 5.5e-05 22.8 0.0 8.1e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 ABC-type uncharacterized transport system ATG16 PF08614.11 OAG34437.1 - 0.001 19.3 2.5 0.001 19.3 2.5 1.7 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) Mating_C PF12737.7 OAG34437.1 - 0.16 11.2 6.8 0.15 11.3 3.7 2.3 2 1 0 2 2 2 0 C-terminal domain of homeodomain 1 DUF4407 PF14362.6 OAG34437.1 - 4.1 6.7 5.3 6.1 6.1 5.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CENP-L PF13092.6 OAG34438.1 - 2.4e-21 76.7 0.0 3.5e-21 76.1 0.0 1.2 1 0 0 1 1 1 1 Kinetochore complex Sim4 subunit Fta1 FYVE PF01363.21 OAG34439.1 - 8.9e-23 80.2 22.6 8.8e-16 57.8 4.6 3.0 3 0 0 3 3 3 2 FYVE zinc finger Rbsn PF11464.8 OAG34439.1 - 5.5e-18 64.4 0.9 1.5e-17 63.0 0.9 1.8 1 0 0 1 1 1 1 Rabenosyn Rab binding domain zf-AN1 PF01428.16 OAG34439.1 - 6.2e-05 23.1 4.1 6.2e-05 23.1 4.1 4.0 3 1 1 4 4 4 1 AN1-like Zinc finger zf-Di19 PF05605.12 OAG34439.1 - 0.0099 16.2 15.3 0.053 13.8 0.1 3.3 3 0 0 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding YqaH PF17448.2 OAG34439.1 - 0.029 14.7 0.3 0.099 13.0 0.2 1.9 1 1 1 2 2 2 0 Uncharacterized YqaH-like bZIP_1 PF00170.21 OAG34439.1 - 0.051 13.7 3.4 3.4 7.8 0.0 3.6 3 0 0 3 3 3 0 bZIP transcription factor zf-C2H2_2 PF12756.7 OAG34439.1 - 0.13 12.6 0.1 0.13 12.6 0.1 3.0 3 0 0 3 3 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 OAG34439.1 - 0.17 12.8 26.7 0.99 10.4 0.0 5.4 5 1 0 5 5 5 0 C2H2-type zinc finger TMF_TATA_bd PF12325.8 OAG34439.1 - 0.28 11.4 10.8 0.37 11.0 0.9 3.3 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding zinc_ribbon_9 PF14369.6 OAG34439.1 - 0.99 9.7 10.3 2.7 8.3 0.2 4.1 4 0 0 4 4 4 0 zinc-ribbon zf-C2H2_9 PF16293.5 OAG34439.1 - 1.8 8.5 4.7 18 5.2 0.0 3.4 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) zf-C2HC5 PF06221.13 OAG34439.1 - 2.5 8.2 18.0 0.48 10.4 0.1 4.5 4 1 1 5 5 5 0 Putative zinc finger motif, C2HC5-type IBR PF01485.21 OAG34439.1 - 5.6 7.3 19.7 0.083 13.1 2.0 3.5 3 1 1 4 4 4 0 IBR domain, a half RING-finger domain zf-ribbon_3 PF13248.6 OAG34439.1 - 7.7 6.1 16.8 1.1 8.7 0.3 4.6 5 0 0 5 5 5 0 zinc-ribbon domain tRNA-synt_1c PF00749.21 OAG34440.1 - 3e-104 348.3 0.0 4.6e-104 347.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 OAG34440.1 - 9.8e-35 120.0 1.0 1.2e-32 113.1 0.0 3.6 4 0 0 4 4 4 1 tRNA synthetases class I (E and Q), anti-codon binding domain E1-E2_ATPase PF00122.20 OAG34441.1 - 6.7e-18 64.9 0.0 1.7e-17 63.5 0.0 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 OAG34441.1 - 1.3e-15 58.3 0.3 1.8e-08 34.9 0.4 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 OAG34441.1 - 8.5e-06 25.8 0.0 0.0022 18.0 0.0 2.8 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 OAG34441.1 - 0.0012 18.7 0.1 0.036 13.8 0.0 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 OAG34441.1 - 0.18 11.3 0.2 1.6 8.2 0.0 2.4 3 0 0 3 3 3 0 Sucrose-6F-phosphate phosphohydrolase DUF3425 PF11905.8 OAG34442.1 - 2.2e-13 50.2 0.3 4.4e-13 49.3 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Wbp11 PF09429.10 OAG34442.1 - 0.011 16.1 1.6 0.019 15.4 1.6 1.3 1 0 0 1 1 1 0 WW domain binding protein 11 bZIP_1 PF00170.21 OAG34442.1 - 0.091 12.9 5.4 0.15 12.2 5.4 1.3 1 0 0 1 1 1 0 bZIP transcription factor bZIP_2 PF07716.15 OAG34442.1 - 2 8.6 8.1 4.5 7.4 8.1 1.5 1 0 0 1 1 1 0 Basic region leucine zipper Pkinase PF00069.25 OAG34443.1 - 1.4e-13 50.9 0.0 1.9e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG34443.1 - 2.7e-07 30.1 0.0 3.9e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAG34443.1 - 3.8e-06 26.0 0.0 8.2e-06 24.8 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 OAG34443.1 - 9.6e-05 22.4 0.1 0.026 14.5 0.0 2.4 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.14 OAG34443.1 - 0.0001 21.8 0.0 0.00016 21.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OAG34443.1 - 0.12 11.7 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Semialdhyde_dhC PF02774.18 OAG34445.1 - 1.4e-37 129.6 0.0 2.2e-37 128.9 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 OAG34445.1 - 7.8e-29 100.6 0.0 2.2e-28 99.1 0.0 1.8 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 OAG34445.1 - 0.01 16.7 0.0 0.02 15.7 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold DapB_N PF01113.20 OAG34445.1 - 0.14 12.3 0.0 0.23 11.6 0.0 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Maf1 PF09174.10 OAG34446.1 - 5.3e-60 202.5 0.0 9.1e-60 201.8 0.0 1.4 1 0 0 1 1 1 1 Maf1 regulator Clat_adaptor_s PF01217.20 OAG34446.1 - 6.3e-52 175.3 2.0 9.9e-52 174.7 2.0 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain HOOK PF05622.12 OAG34447.1 - 8.4e-07 27.5 18.5 8.4e-07 27.5 18.5 2.8 2 1 1 3 3 3 2 HOOK protein Filament PF00038.21 OAG34447.1 - 0.00012 21.8 14.4 0.00012 21.8 14.4 4.0 2 1 2 4 4 4 1 Intermediate filament protein HAP1_N PF04849.13 OAG34447.1 - 0.00051 19.3 4.2 0.00051 19.3 4.2 4.1 1 1 1 3 3 3 1 HAP1 N-terminal conserved region ADIP PF11559.8 OAG34447.1 - 0.0017 18.5 3.4 0.0017 18.5 3.4 4.9 3 1 2 5 5 5 1 Afadin- and alpha -actinin-Binding TPR_MLP1_2 PF07926.12 OAG34447.1 - 0.0026 17.8 15.0 0.0026 17.8 15.0 6.1 4 1 1 5 5 5 1 TPR/MLP1/MLP2-like protein ZapB PF06005.12 OAG34447.1 - 0.0055 17.1 3.1 0.0055 17.1 3.1 6.6 5 1 2 7 7 7 1 Cell division protein ZapB Ribosomal_S13 PF00416.22 OAG34447.1 - 0.016 15.6 7.5 1.4 9.3 0.5 3.1 2 2 0 2 2 2 0 Ribosomal protein S13/S18 Surfac_D-trimer PF09006.11 OAG34447.1 - 0.08 12.8 0.2 0.27 11.1 0.1 2.0 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation Bacillus_HBL PF05791.11 OAG34447.1 - 1.1 9.0 11.4 0.43 10.4 1.6 3.6 2 1 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) DUF5565 PF17720.1 OAG34449.1 - 0.14 11.0 0.0 0.24 10.2 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5565) GST_N PF02798.20 OAG34450.1 - 2.1e-14 53.6 0.0 3.2e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 OAG34450.1 - 2.2e-13 50.4 0.0 3.7e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OAG34450.1 - 1.1e-10 41.6 0.0 2e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 OAG34450.1 - 6.6e-08 32.7 0.0 1.4e-07 31.7 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAG34450.1 - 8.7e-08 32.1 0.2 2.5e-07 30.6 0.2 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OAG34450.1 - 0.00034 20.7 0.0 0.00069 19.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Zn_clus PF00172.18 OAG34451.1 - 2.4e-07 30.8 7.2 5.6e-07 29.6 7.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NAD_binding_10 PF13460.6 OAG34452.1 - 1.4e-19 70.7 0.0 1.6e-19 70.5 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding DIOX_N PF14226.6 OAG34452.1 - 0.048 14.4 0.0 0.078 13.7 0.0 1.3 1 0 0 1 1 1 0 non-haem dioxygenase in morphine synthesis N-terminal PUMA PF15826.5 OAG34454.1 - 0.05 13.8 0.6 0.058 13.6 0.6 1.4 1 1 0 1 1 1 0 Bcl-2-binding component 3, p53 upregulated modulator of apoptosis Meth_synt_2 PF01717.18 OAG34456.1 - 5.2e-05 22.7 0.0 0.0061 15.9 0.0 2.2 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain 2C_adapt PF08793.10 OAG34456.1 - 0.04 14.1 0.0 0.11 12.7 0.0 1.7 1 0 0 1 1 1 0 2-cysteine adaptor domain SelK_SelG PF10961.8 OAG34457.1 - 2.6e-06 27.9 26.7 0.0032 18.0 26.7 2.2 1 1 0 1 1 1 1 Selenoprotein SelK_SelG GRP PF07172.11 OAG34457.1 - 0.028 15.1 17.5 0.04 14.6 17.5 1.2 1 0 0 1 1 1 0 Glycine rich protein family LIAS_N PF16881.5 OAG34458.1 - 1.3e-26 93.1 0.0 2.9e-26 92.0 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 OAG34458.1 - 2.3e-13 50.9 0.0 3.5e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily DUF5519 PF17648.1 OAG34459.1 - 0.00044 20.1 0.1 0.00077 19.3 0.1 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5519) BAG PF02179.16 OAG34460.1 - 5.7e-14 52.3 0.0 1.2e-13 51.3 0.0 1.5 1 0 0 1 1 1 1 BAG domain ubiquitin PF00240.23 OAG34460.1 - 0.0012 18.6 0.0 0.0023 17.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family OmpH PF03938.14 OAG34462.1 - 0.0016 18.8 1.4 0.0028 18.0 1.4 1.3 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) bZIP_1 PF00170.21 OAG34462.1 - 0.0037 17.3 10.8 0.0066 16.5 10.8 1.4 1 0 0 1 1 1 1 bZIP transcription factor DUF4407 PF14362.6 OAG34462.1 - 0.0082 15.5 1.2 0.0082 15.5 1.2 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4407) APG6_N PF17675.1 OAG34462.1 - 0.029 14.9 6.7 0.046 14.3 6.7 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF5082 PF16888.5 OAG34462.1 - 0.054 13.8 0.2 0.12 12.6 0.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) RasGAP_C PF03836.15 OAG34462.1 - 0.057 13.6 0.3 0.088 13.0 0.3 1.3 1 0 0 1 1 1 0 RasGAP C-terminus ADIP PF11559.8 OAG34462.1 - 0.071 13.2 8.9 0.11 12.6 8.2 1.5 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding Exonuc_VII_L PF02601.15 OAG34462.1 - 0.075 12.6 0.4 0.089 12.3 0.4 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Spc7 PF08317.11 OAG34462.1 - 0.078 11.8 4.0 0.12 11.2 4.0 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF5595 PF18077.1 OAG34462.1 - 0.084 13.0 0.7 0.15 12.2 0.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5595) TACC_C PF05010.14 OAG34462.1 - 0.097 12.5 5.6 0.15 11.8 5.6 1.2 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal ATG16 PF08614.11 OAG34462.1 - 0.15 12.3 9.6 0.24 11.6 9.6 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Phage_TTP_12 PF16461.5 OAG34462.1 - 0.15 11.7 0.1 0.26 11.0 0.1 1.3 1 0 0 1 1 1 0 Lambda phage tail tube protein, TTP HAUS6_N PF14661.6 OAG34462.1 - 0.68 9.5 4.5 1.1 8.9 4.5 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus TMF_DNA_bd PF12329.8 OAG34462.1 - 0.87 9.6 3.8 1.6 8.8 3.8 1.5 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Prominin PF05478.11 OAG34462.1 - 2.6 5.9 8.9 0.081 10.9 0.4 1.9 2 0 0 2 2 2 0 Prominin SlyX PF04102.12 OAG34462.1 - 3.5 8.3 7.8 0.36 11.5 1.6 2.4 2 1 1 3 3 2 0 SlyX Lactonase PF10282.9 OAG34463.1 - 4.3e-05 22.9 0.1 0.011 15.1 0.0 3.2 2 2 2 4 4 4 2 Lactonase, 7-bladed beta-propeller DUF1815 PF08844.10 OAG34463.1 - 0.17 11.9 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1815) TRI12 PF06609.13 OAG34464.1 - 4.3e-30 104.7 13.0 5.7e-30 104.3 13.0 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG34464.1 - 2.8e-19 69.3 48.3 2.8e-19 69.2 36.9 3.0 1 1 0 2 2 2 2 Major Facilitator Superfamily Dicty_CAR PF05462.11 OAG34465.1 - 1.4e-06 27.7 0.8 1.4e-06 27.7 0.8 2.1 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor Git3 PF11710.8 OAG34465.1 - 7.7e-05 22.6 2.0 7.7e-05 22.6 2.0 1.7 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 DUF2796 PF10986.8 OAG34466.1 - 0.014 15.4 6.7 0.021 14.8 6.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) DUF3040 PF11239.8 OAG34466.1 - 0.2 12.0 0.2 0.29 11.4 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) Nop14 PF04147.12 OAG34466.1 - 0.81 7.8 16.4 0.92 7.6 16.4 1.0 1 0 0 1 1 1 0 Nop14-like family RRN3 PF05327.11 OAG34466.1 - 1.1 7.8 11.3 1.3 7.5 11.3 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 SDA1 PF05285.12 OAG34466.1 - 3.2 7.1 14.2 4 6.8 14.2 1.1 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 OAG34466.1 - 6.6 6.0 13.8 7.7 5.7 13.8 1.1 1 0 0 1 1 1 0 BUD22 Polysacc_deac_1 PF01522.21 OAG34468.1 - 1.9e-16 60.1 0.2 3.3e-16 59.3 0.0 1.5 2 0 0 2 2 2 1 Polysaccharide deacetylase DUF2334 PF10096.9 OAG34468.1 - 1.1e-05 25.3 0.2 2e-05 24.4 0.2 1.5 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) Peroxidase_2 PF01328.17 OAG34468.1 - 0.00062 20.4 0.0 0.00092 19.8 0.0 1.2 1 0 0 1 1 1 1 Peroxidase, family 2 DUF2194 PF09960.9 OAG34468.1 - 0.0091 14.4 0.0 0.011 14.1 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein conserved in bacteria (DUF2194) HeH PF12949.7 OAG34468.1 - 0.15 11.8 1.3 3 7.6 0.0 2.6 3 0 0 3 3 3 0 HeH/LEM domain PhetRS_B1 PF18262.1 OAG34468.1 - 0.17 12.1 0.0 2.2 8.6 0.0 2.5 2 1 0 2 2 2 0 Phe-tRNA synthetase beta subunit B1 domain 2OG-FeII_Oxy_2 PF13532.6 OAG34469.1 - 1.1e-14 55.1 0.0 7.9e-13 49.0 0.0 2.0 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily T2SSC PF11356.8 OAG34469.1 - 0.039 13.8 0.0 0.071 13.0 0.0 1.3 1 0 0 1 1 1 0 Type II secretion system protein C MBOAT_2 PF13813.6 OAG34470.1 - 7.8e-18 64.5 2.5 1.5e-17 63.7 0.8 2.4 3 0 0 3 3 3 1 Membrane bound O-acyl transferase family SMK-1 PF04802.15 OAG34471.1 - 1.7e-78 262.8 6.3 2.8e-78 262.1 6.3 1.4 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 MIP-T3 PF10243.9 OAG34471.1 - 0.016 15.2 0.4 0.085 12.9 0.1 2.5 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 CH-like domain RNA_pol_Rpb2_2 PF04561.14 OAG34471.1 - 0.11 12.2 2.3 12 5.5 0.2 3.2 2 1 0 3 3 3 0 RNA polymerase Rpb2, domain 2 Glyoxalase_3 PF13468.6 OAG34472.1 - 2.5e-18 66.8 0.0 8.6e-18 65.0 0.0 1.9 2 1 0 2 2 2 1 Glyoxalase-like domain adh_short_C2 PF13561.6 OAG34473.1 - 1.1e-42 146.1 0.0 1.4e-42 145.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG34473.1 - 5.3e-39 133.7 0.0 1.1e-38 132.7 0.0 1.4 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 OAG34473.1 - 2.2e-07 31.0 0.1 3.5e-07 30.3 0.1 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG34473.1 - 0.019 14.4 0.0 0.098 12.1 0.0 2.1 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAG34473.1 - 0.16 11.4 0.0 5.2 6.4 0.0 2.3 3 0 0 3 3 3 0 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 OAG34473.1 - 0.2 10.7 0.0 0.3 10.2 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Arrestin_C PF02752.22 OAG34474.1 - 4.1e-10 40.2 0.6 2.6e-08 34.4 0.6 2.5 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain DUF4106 PF13388.6 OAG34474.1 - 0.12 11.6 1.2 0.25 10.5 1.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) bZIP_1 PF00170.21 OAG34475.1 - 5.6e-06 26.3 6.7 8.9e-06 25.7 6.7 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 OAG34475.1 - 0.00098 19.2 7.4 0.0019 18.3 7.4 1.4 1 0 0 1 1 1 1 Basic region leucine zipper Nop53 PF07767.11 OAG34475.1 - 0.022 14.1 2.3 0.037 13.4 2.3 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Vir_act_alpha_C PF10400.9 OAG34475.1 - 0.071 13.8 3.4 0.13 13.0 3.4 1.4 1 0 0 1 1 1 0 Virulence activator alpha C-term bZIP_Maf PF03131.17 OAG34475.1 - 1.7 9.2 9.3 0.98 10.0 7.3 1.6 2 0 0 2 2 2 0 bZIP Maf transcription factor SlyX PF04102.12 OAG34475.1 - 4.4 8.0 9.6 0.13 12.9 0.5 2.7 3 0 0 3 3 3 0 SlyX Stm1_N PF09598.10 OAG34476.1 - 1.3e-16 61.2 3.0 1.3e-16 61.2 3.0 3.4 3 1 0 3 3 3 1 Stm1 mIF3 PF14877.6 OAG34476.1 - 0.047 13.4 1.2 0.073 12.7 1.2 1.2 1 0 0 1 1 1 0 Mitochondrial translation initiation factor U79_P34 PF03064.16 OAG34476.1 - 7.2 5.9 8.6 12 5.2 8.6 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 p450 PF00067.22 OAG34477.1 - 3.6e-68 230.4 0.0 4.7e-68 230.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Nitroreductase PF00881.24 OAG34478.1 - 1.4e-14 54.5 0.0 1.7e-14 54.2 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family BDV_P40 PF06407.11 OAG34478.1 - 0.0096 15.1 0.0 0.013 14.6 0.0 1.1 1 0 0 1 1 1 1 Borna disease virus P40 protein TRI12 PF06609.13 OAG34479.1 - 2e-76 257.7 22.9 2.9e-76 257.2 22.9 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG34479.1 - 1.1e-20 74.0 44.4 1.1e-20 74.0 44.4 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF3237 PF11578.8 OAG34479.1 - 2e-20 73.1 0.1 3.6e-20 72.3 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) HHH_5 PF14520.6 OAG34479.1 - 0.034 14.8 0.1 0.075 13.6 0.1 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix domain FAD_binding_2 PF00890.24 OAG34480.1 - 2.1e-46 158.8 0.4 3.1e-46 158.3 0.4 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAG34480.1 - 5e-10 39.5 0.7 4.7e-09 36.3 0.7 2.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 OAG34480.1 - 1.3e-06 28.0 0.8 5.2e-06 26.1 0.8 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG34480.1 - 1.5e-05 24.4 1.2 0.00022 20.6 0.1 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAG34480.1 - 0.0098 14.6 2.6 0.01 14.6 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein AlaDh_PNT_C PF01262.21 OAG34480.1 - 0.013 14.8 0.7 0.031 13.6 0.7 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 OAG34480.1 - 0.021 14.2 0.4 0.05 13.0 0.2 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 OAG34480.1 - 0.024 13.9 0.5 0.052 12.8 0.4 1.4 1 1 0 1 1 1 0 FAD binding domain IlvN PF07991.12 OAG34480.1 - 0.069 12.7 0.2 0.18 11.4 0.2 1.6 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain GIDA PF01134.22 OAG34480.1 - 0.11 11.6 3.2 0.18 10.8 3.2 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 OAG34480.1 - 0.14 11.4 0.0 2.5 7.3 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.19 OAG34480.1 - 0.19 11.0 1.1 1.6 8.0 0.1 2.6 2 1 1 3 3 3 0 GMC oxidoreductase Pyr_redox PF00070.27 OAG34480.1 - 0.54 10.9 1.8 27 5.4 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Peptidase_M3 PF01432.20 OAG34481.1 - 9.7e-116 387.7 0.0 1.5e-115 387.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M91 PF14891.6 OAG34481.1 - 0.17 12.2 0.0 0.66 10.3 0.0 1.9 2 0 0 2 2 2 0 Effector protein LapA_dom PF06305.11 OAG34482.1 - 0.2 11.5 0.0 0.2 11.5 0.0 3.5 3 1 1 4 4 4 0 Lipopolysaccharide assembly protein A domain DUF4231 PF14015.6 OAG34482.1 - 0.26 11.8 1.1 0.88 10.1 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) DUF2721 PF11026.8 OAG34482.1 - 2.9 7.8 7.9 0.32 10.9 0.2 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2721) FMO-like PF00743.19 OAG34483.1 - 1.4e-24 86.5 0.0 9.6e-17 60.6 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OAG34483.1 - 4.7e-08 32.6 0.0 2.3e-07 30.4 0.0 1.8 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG34483.1 - 0.0041 16.3 0.1 0.023 13.8 0.0 2.0 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 OAG34483.1 - 0.0042 16.4 0.0 0.084 12.1 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ApoO PF09769.9 OAG34484.1 - 5e-43 146.2 0.5 6.1e-41 139.4 0.0 2.1 2 0 0 2 2 2 2 Apolipoprotein O UPF0113_N PF17833.1 OAG34485.1 - 5.9e-27 94.1 0.0 8.1e-27 93.6 0.0 1.2 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 OAG34485.1 - 6.7e-22 77.6 0.0 1e-21 77.0 0.0 1.3 1 0 0 1 1 1 1 UPF0113 PUA domain PUA PF01472.20 OAG34485.1 - 0.046 13.7 0.0 0.081 12.9 0.0 1.4 1 0 0 1 1 1 0 PUA domain NOC3p PF07540.11 OAG34486.1 - 3.3e-28 98.0 2.2 7.7e-28 96.8 0.0 2.6 2 0 0 2 2 2 1 Nucleolar complex-associated protein CBF PF03914.17 OAG34486.1 - 5.2e-19 68.9 0.1 2e-18 67.0 0.0 2.1 2 0 0 2 2 2 1 CBF/Mak21 family AMPK1_CBM PF16561.5 OAG34487.1 - 5.5e-14 52.1 0.0 8.8e-14 51.5 0.0 1.3 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase Isochorismatase PF00857.20 OAG34488.1 - 3.1e-24 86.1 0.2 3.9e-24 85.8 0.2 1.1 1 0 0 1 1 1 1 Isochorismatase family Tweety PF04906.13 OAG34490.1 - 0.072 11.7 0.0 0.31 9.6 0.0 1.9 2 0 0 2 2 2 0 Tweety Pro-NT_NN PF07421.11 OAG34491.1 - 0.0029 17.9 0.1 0.0068 16.7 0.1 1.6 1 0 0 1 1 1 1 Neurotensin/neuromedin N precursor FANCI_S4 PF14678.6 OAG34491.1 - 0.016 14.3 0.4 0.028 13.6 0.4 1.2 1 0 0 1 1 1 0 FANCI solenoid 4 DUF4315 PF14193.6 OAG34491.1 - 0.037 14.0 0.3 0.11 12.5 0.3 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4315) Nrap_D4 PF17405.2 OAG34491.1 - 0.1 11.9 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 Nrap protein nucleotidyltransferase domain 4 PTR2 PF00854.21 OAG34492.1 - 9.8e-84 281.5 8.9 1.3e-83 281.1 8.9 1.1 1 0 0 1 1 1 1 POT family MFS_1 PF07690.16 OAG34492.1 - 8.9e-07 28.1 28.5 2.5e-06 26.6 25.6 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF3042 PF11240.8 OAG34492.1 - 0.18 11.9 0.0 0.82 9.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3042) Pkinase PF00069.25 OAG34493.1 - 2.6e-67 227.0 0.0 3.4e-67 226.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG34493.1 - 4.2e-28 98.3 0.0 5.9e-28 97.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAG34493.1 - 0.00016 21.1 0.0 0.00029 20.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OAG34493.1 - 0.0056 15.7 0.0 0.015 14.3 0.0 1.5 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 OAG34493.1 - 0.0059 16.6 0.0 0.0083 16.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 OAG34493.1 - 0.012 14.7 0.0 0.018 14.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 tRNA-synt_1b PF00579.25 OAG34494.1 - 5.2e-63 213.1 0.0 6.7e-63 212.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Sugar_tr PF00083.24 OAG34495.1 - 3.6e-78 263.5 25.6 4.2e-78 263.2 25.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG34495.1 - 1.2e-15 57.3 32.8 1.2e-15 57.3 32.8 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF3906 PF13046.6 OAG34495.1 - 0.065 13.3 0.2 0.13 12.4 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3906) HET PF06985.11 OAG34496.1 - 2.8e-15 57.0 0.0 8.6e-15 55.4 0.0 1.8 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Nop14 PF04147.12 OAG34496.1 - 0.0063 14.8 32.6 0.0082 14.4 32.6 1.1 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.12 OAG34496.1 - 0.11 11.8 36.3 0.16 11.3 36.3 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 OAG34496.1 - 0.29 9.4 27.2 0.58 8.4 27.2 1.4 1 0 0 1 1 1 0 CDC45-like protein Mpp10 PF04006.12 OAG34496.1 - 0.59 8.5 28.6 0.83 8.0 28.6 1.1 1 0 0 1 1 1 0 Mpp10 protein SAPS PF04499.15 OAG34496.1 - 0.69 8.6 12.0 0.94 8.2 12.0 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DNA_pol_phi PF04931.13 OAG34496.1 - 2.3 6.2 53.6 4.6 5.2 53.6 1.4 1 0 0 1 1 1 0 DNA polymerase phi AAA PF00004.29 OAG34497.1 - 2.9e-32 111.9 0.0 4.5e-30 104.8 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OAG34497.1 - 1.3e-08 34.5 0.1 6.8e-08 32.2 0.1 2.3 2 0 0 2 2 1 1 AAA+ lid domain AAA_33 PF13671.6 OAG34497.1 - 4.5e-06 26.9 0.1 0.00097 19.3 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OAG34497.1 - 0.00031 21.2 3.8 0.02 15.3 0.0 3.3 2 1 2 4 4 4 1 AAA ATPase domain AAA_22 PF13401.6 OAG34497.1 - 0.00033 20.9 0.8 0.013 15.8 0.1 3.2 3 1 0 3 3 1 1 AAA domain IstB_IS21 PF01695.17 OAG34497.1 - 0.0004 20.2 0.1 0.0038 17.0 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein RuvB_N PF05496.12 OAG34497.1 - 0.0028 17.4 0.0 0.0073 16.1 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 OAG34497.1 - 0.0028 18.0 0.0 0.06 13.7 0.0 2.5 2 0 0 2 2 2 1 RNA helicase AAA_24 PF13479.6 OAG34497.1 - 0.0035 17.1 0.0 0.0091 15.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain Vps4_C PF09336.10 OAG34497.1 - 0.0046 16.9 0.0 0.014 15.4 0.0 1.8 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_14 PF13173.6 OAG34497.1 - 0.0065 16.5 0.0 0.038 14.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 OAG34497.1 - 0.007 16.2 0.1 0.029 14.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 OAG34497.1 - 0.021 15.4 0.0 0.087 13.4 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 OAG34497.1 - 0.032 14.3 0.0 0.21 11.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ATPase_2 PF01637.18 OAG34497.1 - 0.047 13.6 0.0 0.24 11.3 0.0 2.0 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea NACHT PF05729.12 OAG34497.1 - 0.05 13.5 0.0 0.21 11.5 0.0 2.1 2 0 0 2 2 1 0 NACHT domain Sigma54_activat PF00158.26 OAG34497.1 - 0.067 12.9 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ABC_tran PF00005.27 OAG34497.1 - 0.08 13.5 0.0 0.79 10.2 0.0 2.7 3 1 0 3 3 3 0 ABC transporter TIP49 PF06068.13 OAG34497.1 - 0.09 12.0 0.1 0.16 11.2 0.1 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain BET PF17035.5 OAG34497.1 - 0.13 12.5 0.0 0.68 10.1 0.0 2.4 1 0 0 1 1 1 0 Bromodomain extra-terminal - transcription regulation Cbl_N PF02262.16 OAG34497.1 - 0.15 12.0 0.0 3.6 7.6 0.0 2.5 1 1 1 2 2 2 0 CBL proto-oncogene N-terminal domain 1 Hydin_ADK PF17213.3 OAG34497.1 - 0.77 10.0 7.5 2.9 8.1 0.1 3.3 4 0 0 4 4 4 0 Hydin Adenylate kinase-like domain Fasciclin PF02469.22 OAG34498.1 - 4.4e-06 26.9 0.5 9.7e-06 25.8 0.5 1.6 1 1 0 1 1 1 1 Fasciclin domain Fungal_trans PF04082.18 OAG34499.1 - 1.1e-24 86.9 0.0 2e-24 86.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aldedh PF00171.22 OAG34500.1 - 6.9e-150 499.6 0.0 7.8e-150 499.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 OAG34500.1 - 0.056 12.9 0.0 2.6 7.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) ECH_1 PF00378.20 OAG34501.1 - 1e-42 146.2 0.0 1.3e-42 145.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAG34501.1 - 1.4e-28 100.4 0.2 9.9e-27 94.3 0.1 1.9 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Mito_carr PF00153.27 OAG34502.1 - 5.9e-52 173.6 4.8 6e-20 71.0 0.1 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein Sugar_tr PF00083.24 OAG34503.1 - 1.2e-85 288.0 28.8 1.4e-85 287.8 28.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG34503.1 - 1.2e-24 86.9 32.7 1.2e-24 86.9 32.7 1.7 2 1 0 2 2 2 1 Major Facilitator Superfamily zf-C3HC4_4 PF15227.6 OAG34503.1 - 0.18 12.0 0.2 0.35 11.0 0.2 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING CoA_transf_3 PF02515.17 OAG34504.1 - 2.5e-121 405.3 0.0 5.8e-69 233.0 0.0 2.0 2 0 0 2 2 2 2 CoA-transferase family III TauD PF02668.16 OAG34505.1 - 1.5e-56 192.1 0.1 2e-56 191.8 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Pyr_redox_2 PF07992.14 OAG34506.1 - 4.1e-11 42.6 0.0 4.8e-07 29.3 0.0 2.9 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 OAG34506.1 - 3.2e-07 29.2 0.0 1.6e-06 26.9 0.0 1.8 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 OAG34506.1 - 9.3e-06 25.0 0.0 8.1e-05 21.9 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 OAG34506.1 - 0.00097 18.5 0.0 0.012 14.9 0.0 2.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 OAG34506.1 - 0.0092 16.0 0.0 0.045 13.8 0.0 2.0 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_8 PF13450.6 OAG34506.1 - 0.0095 16.2 0.1 0.044 14.0 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 OAG34506.1 - 0.097 13.2 0.2 2.5 8.7 0.0 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Abhydrolase_3 PF07859.13 OAG34507.1 - 1.5e-51 175.3 0.0 1.9e-51 174.9 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 OAG34507.1 - 2.2e-14 53.1 0.0 2.7e-14 52.8 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 OAG34507.1 - 0.00013 21.5 0.0 0.00024 20.7 0.0 1.4 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 OAG34507.1 - 0.0024 17.7 0.3 0.0058 16.5 0.0 1.8 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.20 OAG34507.1 - 0.021 14.5 0.0 0.043 13.5 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 OAG34507.1 - 0.041 13.5 0.0 0.062 12.9 0.0 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) COesterase PF00135.28 OAG34507.1 - 0.052 12.4 0.0 0.8 8.5 0.0 2.0 2 0 0 2 2 2 0 Carboxylesterase family Hydrolase_4 PF12146.8 OAG34507.1 - 0.055 12.7 0.1 0.29 10.4 0.0 2.2 2 1 0 2 2 2 0 Serine aminopeptidase, S33 Cupin_2 PF07883.11 OAG34508.1 - 5.3e-06 26.0 0.1 8.3e-06 25.4 0.1 1.2 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 OAG34508.1 - 0.00011 22.1 0.1 0.00014 21.8 0.1 1.1 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_6 PF12852.7 OAG34508.1 - 0.00026 20.7 0.1 0.00032 20.5 0.1 1.2 1 0 0 1 1 1 1 Cupin Cupin_1 PF00190.22 OAG34508.1 - 0.00067 19.3 0.0 0.001 18.7 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.12 OAG34508.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF861) FMO-like PF00743.19 OAG34509.1 - 4e-13 48.6 0.0 1.3e-10 40.4 0.0 2.8 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OAG34509.1 - 3.6e-12 46.3 0.0 1.4e-11 44.5 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAG34509.1 - 1e-08 34.8 0.0 2.4e-05 23.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAG34509.1 - 9.8e-07 28.9 0.6 9.7e-05 22.4 0.0 3.1 4 0 0 4 4 4 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 OAG34509.1 - 1.1e-05 24.9 0.0 6.9e-05 22.3 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAG34509.1 - 3.2e-05 23.7 0.0 1.1 8.7 0.0 3.2 3 0 0 3 3 3 2 FAD dependent oxidoreductase K_oxygenase PF13434.6 OAG34509.1 - 3.3e-05 23.2 0.0 0.12 11.4 0.0 3.2 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 OAG34509.1 - 0.01 15.1 0.0 0.091 12.0 0.0 2.3 2 0 0 2 2 2 0 Thi4 family GIDA PF01134.22 OAG34509.1 - 0.15 11.1 0.2 0.48 9.5 0.0 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A Fungal_trans PF04082.18 OAG34510.1 - 1.1e-17 64.0 0.2 1.6e-17 63.4 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG34510.1 - 9.9e-05 22.4 3.7 0.00017 21.7 3.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ECH_1 PF00378.20 OAG34511.1 - 9.5e-36 123.4 0.0 1.1e-35 123.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAG34511.1 - 5.7e-18 65.5 0.0 7.3e-18 65.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase 7TM_GPCR_Srt PF10321.9 OAG34512.1 - 0.091 11.7 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srt Pyr_redox_3 PF13738.6 OAG34513.1 - 8.9e-12 44.9 0.0 2.9e-11 43.2 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 OAG34513.1 - 1.5e-10 40.2 0.0 4.2e-10 38.7 0.0 1.6 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OAG34513.1 - 2.3e-09 37.4 0.0 9.5e-08 32.2 0.0 2.7 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAG34513.1 - 6.1e-09 35.5 0.0 3e-07 30.0 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAG34513.1 - 2.2e-08 33.7 0.0 2.8e-05 23.5 0.0 2.3 2 0 0 2 2 2 2 Thi4 family K_oxygenase PF13434.6 OAG34513.1 - 1.8e-07 30.6 0.0 4.1e-05 22.9 0.0 2.4 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 OAG34513.1 - 1.8e-06 27.8 0.3 0.00015 21.5 0.1 3.0 3 1 1 4 4 4 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 OAG34513.1 - 0.00069 18.8 0.1 0.013 14.6 0.0 2.5 3 0 0 3 3 3 1 Lycopene cyclase protein Pyr_redox PF00070.27 OAG34513.1 - 0.00095 19.7 0.0 2.3 8.8 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAG34513.1 - 0.0095 15.9 1.1 5.8 6.9 0.1 3.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 OAG34513.1 - 0.088 11.9 0.0 0.29 10.2 0.0 1.9 2 0 0 2 2 2 0 FAD binding domain Mqo PF06039.15 OAG34513.1 - 0.12 11.0 0.2 2.5 6.5 0.0 2.4 2 1 1 3 3 3 0 Malate:quinone oxidoreductase (Mqo) Shikimate_DH PF01488.20 OAG34513.1 - 0.2 11.7 0.1 2.2 8.4 0.0 2.4 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase adh_short PF00106.25 OAG34514.1 - 3.1e-37 127.9 0.1 7.2e-37 126.7 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG34514.1 - 1.9e-26 93.0 0.0 2.7e-26 92.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG34514.1 - 6.6e-06 26.1 1.4 0.0001 22.2 1.1 2.5 2 1 0 2 2 2 1 KR domain Epimerase PF01370.21 OAG34514.1 - 0.014 14.9 0.0 0.024 14.1 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family TRI12 PF06609.13 OAG34515.1 - 4.4e-29 101.4 26.1 5.3e-29 101.1 26.1 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG34515.1 - 2.5e-12 46.4 56.5 1.2e-11 44.1 49.1 3.3 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG34515.1 - 8.6e-08 31.5 33.9 2.1e-06 26.9 9.9 3.2 3 1 0 3 3 3 2 Sugar (and other) transporter HemY_N PF07219.13 OAG34515.1 - 0.98 9.6 3.4 1.1 9.4 0.1 2.8 2 0 0 2 2 2 0 HemY protein N-terminus adh_short PF00106.25 OAG34516.1 - 1e-35 123.0 0.0 1.7e-35 122.3 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG34516.1 - 2.3e-21 76.4 0.0 3.1e-21 76.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG34516.1 - 1.9e-07 31.1 0.0 6.5e-07 29.4 0.0 1.8 2 1 0 2 2 2 1 KR domain DUF1776 PF08643.10 OAG34516.1 - 9.8e-05 21.9 0.1 0.00014 21.3 0.1 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) YCII PF03795.14 OAG34517.1 - 2.6e-12 47.0 0.0 3e-12 46.8 0.0 1.0 1 0 0 1 1 1 1 YCII-related domain Lactamase_B PF00753.27 OAG34518.1 - 7.2e-09 35.9 3.6 2.2e-08 34.4 3.6 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OAG34518.1 - 0.015 14.9 0.1 0.028 13.9 0.1 1.5 1 1 0 1 1 1 0 Beta-lactamase superfamily domain Fungal_trans PF04082.18 OAG34520.1 - 4.8e-15 55.3 0.1 7.2e-15 54.7 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain NAD_binding_2 PF03446.15 OAG34521.1 - 9e-31 107.2 0.0 1.3e-30 106.6 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 OAG34521.1 - 4.4e-25 88.3 0.0 6.2e-25 87.8 0.0 1.2 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 2-Hacid_dh_C PF02826.19 OAG34521.1 - 0.004 16.5 0.0 0.0068 15.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 OAG34521.1 - 0.0043 17.9 0.0 0.0069 17.2 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold OCD_Mu_crystall PF02423.15 OAG34521.1 - 0.03 13.2 0.0 0.046 12.6 0.0 1.2 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family F420_oxidored PF03807.17 OAG34521.1 - 0.042 14.4 0.0 0.081 13.5 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 OAG34521.1 - 0.042 13.9 0.0 0.084 12.9 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 OAG34521.1 - 0.043 14.1 0.0 0.069 13.4 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain 3HCDH_N PF02737.18 OAG34521.1 - 0.062 13.2 0.0 0.091 12.6 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ras PF00071.22 OAG34522.1 - 9.3e-53 178.1 0.2 1.4e-51 174.4 0.2 2.0 1 1 0 1 1 1 1 Ras family Roc PF08477.13 OAG34522.1 - 1e-18 67.7 0.0 1.6e-17 63.9 0.0 2.2 1 1 1 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAG34522.1 - 0.00086 18.8 0.1 0.0018 17.7 0.1 1.5 2 0 0 2 2 2 1 ADP-ribosylation factor family Septin PF00735.18 OAG34522.1 - 0.081 12.2 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Septin AAA PF00004.29 OAG34522.1 - 0.17 12.3 0.0 45 4.5 0.0 3.1 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) CbiA PF01656.23 OAG34522.1 - 0.17 11.9 0.1 0.55 10.3 0.1 1.8 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_25 PF13481.6 OAG34522.1 - 0.18 11.4 0.0 0.32 10.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain FeoB_N PF02421.18 OAG34522.1 - 0.19 11.2 0.1 3.4 7.2 0.0 2.4 2 1 1 3 3 3 0 Ferrous iron transport protein B GST_N_2 PF13409.6 OAG34523.1 - 8.9e-20 70.8 0.0 1.5e-19 70.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAG34523.1 - 7.4e-15 54.7 0.0 1.5e-14 53.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OAG34523.1 - 7e-07 29.4 0.0 1.5e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OAG34523.1 - 2e-05 24.7 0.1 4.7e-05 23.5 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 OAG34523.1 - 0.0014 19.0 0.0 0.012 16.0 0.0 2.1 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain HAD_2 PF13419.6 OAG34524.1 - 4.7e-09 36.6 0.0 6.2e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OAG34524.1 - 8.2e-09 36.0 0.0 1e-08 35.8 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OAG34524.1 - 0.00058 19.9 0.0 0.0014 18.6 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like Mcp5_PH PF12814.7 OAG34525.1 - 1.5e-41 141.3 2.1 1.9e-39 134.5 2.1 2.5 1 1 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology Fez1 PF06818.15 OAG34525.1 - 8e-05 23.2 10.6 0.00015 22.3 10.6 1.3 1 0 0 1 1 1 1 Fez1 TPR_MLP1_2 PF07926.12 OAG34525.1 - 0.069 13.2 16.9 0.17 11.9 6.2 2.3 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein ADIP PF11559.8 OAG34525.1 - 0.098 12.7 12.9 0.021 14.9 2.8 2.3 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Peptidase_C4 PF00863.19 OAG34525.1 - 0.12 11.7 0.0 0.26 10.5 0.0 1.5 1 0 0 1 1 1 0 Peptidase family C4 Elongin_A PF06881.11 OAG34526.1 - 1.6e-30 105.7 0.7 1.6e-30 105.7 0.7 1.9 2 0 0 2 2 2 1 RNA polymerase II transcription factor SIII (Elongin) subunit A DUF2513 PF10711.9 OAG34526.1 - 0.16 12.3 0.1 1.2 9.5 0.0 2.3 2 0 0 2 2 2 0 Hypothetical protein (DUF2513) THOC7 PF05615.13 OAG34527.1 - 3.8e-36 124.3 2.4 3.8e-36 124.3 2.4 2.2 1 1 1 2 2 2 1 Tho complex subunit 7 KASH_CCD PF14662.6 OAG34527.1 - 0.0058 16.5 10.4 0.0058 16.5 10.4 1.5 1 1 1 2 2 2 1 Coiled-coil region of CCDC155 or KASH Peroxin-13_N PF04088.13 OAG34527.1 - 0.1 12.9 0.6 0.15 12.3 0.6 1.3 1 0 0 1 1 1 0 Peroxin 13, N-terminal region Spc7 PF08317.11 OAG34527.1 - 0.14 11.0 12.2 0.2 10.5 12.2 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein YabA PF06156.13 OAG34527.1 - 0.25 12.0 5.7 0.12 13.0 1.0 2.2 1 1 1 2 2 2 0 Initiation control protein YabA FAM76 PF16046.5 OAG34527.1 - 1.7 7.9 4.5 2.6 7.3 4.5 1.2 1 0 0 1 1 1 0 FAM76 protein Fib_alpha PF08702.10 OAG34527.1 - 2.5 8.3 5.4 3.9 7.7 5.4 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Syntaxin-6_N PF09177.11 OAG34527.1 - 2.8 8.6 9.2 7.4 7.2 0.6 2.3 1 1 1 2 2 2 0 Syntaxin 6, N-terminal V_ATPase_I PF01496.19 OAG34527.1 - 3.5 5.4 6.4 4.3 5.1 6.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TBCA PF02970.16 OAG34528.1 - 9.1e-23 80.4 8.7 9.1e-23 80.4 8.7 1.3 1 1 0 1 1 1 1 Tubulin binding cofactor A FlgN PF05130.12 OAG34528.1 - 0.036 14.6 6.8 0.048 14.2 6.8 1.2 1 0 0 1 1 1 0 FlgN protein PCRF PF03462.18 OAG34528.1 - 0.044 13.6 5.5 0.053 13.4 5.5 1.1 1 0 0 1 1 1 0 PCRF domain Med9 PF07544.13 OAG34528.1 - 0.28 11.3 8.2 0.08 13.0 1.3 2.3 1 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF4404 PF14357.6 OAG34528.1 - 1.5 9.5 7.1 0.3 11.8 1.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) Atg14 PF10186.9 OAG34528.1 - 5.5 6.0 8.3 6.5 5.8 8.3 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ADH_zinc_N PF00107.26 OAG34529.1 - 8.4e-05 22.6 0.1 0.00013 21.9 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Band_7 PF01145.25 OAG34531.1 - 2e-17 63.8 0.3 2e-17 63.8 0.3 3.4 2 1 0 2 2 2 1 SPFH domain / Band 7 family SNAD2 PF18745.1 OAG34531.1 - 0.46 10.2 2.6 0.7 9.6 2.2 1.6 1 1 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 2 Pkinase PF00069.25 OAG34532.1 - 2.7e-34 118.8 0.0 1.3e-32 113.2 0.0 2.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG34532.1 - 6.3e-20 71.5 0.0 1.2e-19 70.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase OMPdecase PF00215.24 OAG34533.1 - 1.8e-71 240.3 0.0 2.1e-71 240.1 0.0 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Vac7 PF12751.7 OAG34534.1 - 2e-137 458.7 1.1 5e-137 457.4 1.1 1.7 1 0 0 1 1 1 1 Vacuolar segregation subunit 7 DUF3824 PF12868.7 OAG34535.1 - 2.9e-18 67.0 49.9 2.9e-18 67.0 49.9 9.1 2 2 7 10 10 10 3 Domain of unknwon function (DUF3824) PA PF02225.22 OAG34535.1 - 0.11 12.5 1.2 11 6.1 0.1 2.9 2 0 0 2 2 2 0 PA domain SfLAP PF11139.8 OAG34535.1 - 0.79 9.1 5.2 19 4.6 5.2 2.5 1 1 0 1 1 1 0 Sap, sulfolipid-1-addressing protein DUF3040 PF11239.8 OAG34536.1 - 2 8.8 5.5 1.1 9.5 3.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) Ribosomal_L44 PF00935.19 OAG34537.1 - 2.3e-36 124.1 12.0 3.9e-36 123.4 12.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L44 Cathelicidins PF00666.17 OAG34537.1 - 0.089 13.1 0.9 0.089 13.1 0.9 1.6 2 0 0 2 2 2 0 Cathelicidin P22_AR_N PF10547.9 OAG34538.1 - 0.083 13.2 0.0 0.96 9.8 0.0 2.3 3 0 0 3 3 3 0 P22_AR N-terminal domain HAD_2 PF13419.6 OAG34540.1 - 5.1e-06 26.7 0.0 1.1e-05 25.5 0.0 1.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OAG34540.1 - 0.013 15.8 0.0 0.024 14.9 0.0 1.4 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Rox3 PF08633.10 OAG34541.1 - 4.2e-55 187.2 2.7 6.3e-55 186.6 2.7 1.3 1 0 0 1 1 1 1 Rox3 mediator complex subunit RdRP_3 PF00998.23 OAG34541.1 - 0.0083 14.9 0.0 0.011 14.5 0.0 1.1 1 0 0 1 1 1 1 Viral RNA dependent RNA polymerase DAO PF01266.24 OAG34542.1 - 4.3e-51 174.6 0.0 5e-51 174.3 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 OAG34542.1 - 1.8e-05 24.1 0.0 3.9e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 OAG34542.1 - 0.0026 18.0 0.2 0.009 16.2 0.2 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 OAG34542.1 - 0.0072 15.5 0.0 0.013 14.7 0.0 1.3 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.12 OAG34542.1 - 0.03 13.4 0.0 0.041 12.9 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_2 PF00890.24 OAG34542.1 - 0.049 12.7 0.4 0.68 8.9 0.3 2.1 2 0 0 2 2 2 0 FAD binding domain NAD_binding_9 PF13454.6 OAG34542.1 - 0.082 12.9 0.1 0.24 11.4 0.1 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding E3_binding PF02817.17 OAG34542.1 - 0.27 11.6 0.6 4.2 7.8 0.0 2.8 3 0 0 3 3 3 0 e3 binding domain DnaJ_C PF01556.18 OAG34543.1 - 8.7e-37 126.5 0.4 1.6e-36 125.6 0.4 1.4 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 OAG34543.1 - 7.5e-22 77.2 2.3 1.4e-21 76.4 2.3 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 OAG34543.1 - 9.7e-14 51.5 20.2 1.7e-13 50.7 20.2 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 OAG34543.1 - 0.025 14.5 19.2 0.22 11.5 6.6 2.5 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 OAG34543.1 - 0.049 13.7 8.6 0.7 9.9 1.2 2.3 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF1356 PF07092.12 OAG34543.1 - 0.38 10.0 5.6 1.5 8.1 0.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1356) zf-RING_10 PF16685.5 OAG34543.1 - 0.77 9.9 6.1 3.6 7.8 0.5 2.3 2 0 0 2 2 2 0 zinc RING finger of MSL2 TackOD1 PF18551.1 OAG34543.1 - 0.83 9.3 8.0 1.2 8.7 0.7 2.2 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 tRNA-synt_1c PF00749.21 OAG34544.1 - 8.6e-87 291.0 0.0 2.2e-86 289.6 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain SNF5 PF04855.12 OAG34545.1 - 3.9e-83 278.9 0.0 8.4e-83 277.8 0.0 1.5 2 0 0 2 2 2 1 SNF5 / SMARCB1 / INI1 WD40 PF00400.32 OAG34545.1 - 1.5e-19 70.0 13.6 0.001 19.8 0.1 7.1 6 1 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG34545.1 - 1.9e-07 31.3 5.1 0.074 13.4 0.0 4.5 3 1 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain TFIIIC_delta PF12657.7 OAG34545.1 - 0.0013 18.7 3.3 0.021 14.8 0.1 2.6 2 1 0 2 2 2 1 Transcription factor IIIC subunit delta N-term Amidohydro_2 PF04909.14 OAG34548.1 - 1.3e-34 120.3 0.1 1.5e-34 120.1 0.1 1.0 1 0 0 1 1 1 1 Amidohydrolase TatD_DNase PF01026.21 OAG34548.1 - 0.0039 16.6 0.0 0.0066 15.9 0.0 1.5 1 0 0 1 1 1 1 TatD related DNase DUF4202 PF13875.6 OAG34549.1 - 2.6e-76 255.7 0.2 2.9e-76 255.5 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4202) Thymosin PF01290.20 OAG34550.1 - 0.6 9.9 5.1 1 9.1 5.1 1.4 1 0 0 1 1 1 0 Thymosin beta-4 family Fungal_trans PF04082.18 OAG34552.1 - 5.4e-26 91.2 0.0 1.2e-25 90.1 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG34552.1 - 1.6e-09 37.7 12.2 2.8e-09 37.0 12.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TIMELESS PF04821.14 OAG34552.1 - 0.14 11.4 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 Timeless protein GAT PF03127.14 OAG34553.1 - 0.039 14.3 0.2 0.039 14.3 0.2 2.7 2 1 1 3 3 3 0 GAT domain UPF0242 PF06785.11 OAG34553.1 - 0.1 12.7 30.2 0.23 11.5 10.9 2.3 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Spc7 PF08317.11 OAG34553.1 - 0.27 10.1 28.6 0.13 11.1 26.1 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF4239 PF14023.6 OAG34553.1 - 1.2 8.8 5.1 2.1 8.0 5.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) Holin_BhlA PF10960.8 OAG34553.1 - 2.1 8.4 6.2 26 4.9 4.9 2.6 2 0 0 2 2 2 0 BhlA holin family SlyX PF04102.12 OAG34553.1 - 3 8.5 23.1 6.7 7.4 0.4 4.6 2 2 2 4 4 4 0 SlyX zf-C4H2 PF10146.9 OAG34553.1 - 3 8.1 15.9 0.56 10.5 11.4 1.8 1 1 1 2 2 2 0 Zinc finger-containing protein HSP70 PF00012.20 OAG34553.1 - 3.1 5.9 14.1 7.1 4.7 13.3 1.8 2 0 0 2 2 2 0 Hsp70 protein APG6_N PF17675.1 OAG34553.1 - 3.6 8.1 27.1 0.16 12.5 19.5 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region TMF_DNA_bd PF12329.8 OAG34553.1 - 6.3 6.9 31.2 4.2 7.4 8.7 3.8 1 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding Isochorismatase PF00857.20 OAG34554.1 - 6.2e-22 78.6 0.0 5.6e-15 56.0 0.0 2.3 2 0 0 2 2 2 2 Isochorismatase family DUF2065 PF09838.9 OAG34554.1 - 0.063 13.3 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2065) SNase PF00565.17 OAG34555.1 - 4.4e-81 268.4 0.8 5.3e-25 88.0 0.0 5.5 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.24 OAG34555.1 - 9.4e-27 93.5 0.0 1.7e-26 92.6 0.0 1.4 1 0 0 1 1 1 1 Tudor domain SMN PF06003.12 OAG34555.1 - 0.025 13.9 0.0 0.059 12.6 0.0 1.6 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Agenet PF05641.12 OAG34555.1 - 0.071 13.6 1.4 0.15 12.5 0.2 2.3 2 0 0 2 2 2 0 Agenet domain GFA PF04828.14 OAG34556.1 - 2.6e-20 72.6 0.0 3.2e-20 72.3 0.0 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme LisH_2 PF16045.5 OAG34556.1 - 0.1 11.6 0.7 0.17 11.0 0.7 1.3 1 0 0 1 1 1 0 LisH Pkinase PF00069.25 OAG34557.1 - 1.1e-64 218.3 0.0 1.4e-64 218.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG34557.1 - 5e-30 104.7 0.0 6.8e-30 104.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAG34557.1 - 0.0021 17.4 0.0 0.0056 16.0 0.0 1.7 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OAG34557.1 - 0.25 10.1 0.0 0.37 9.5 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase peroxidase PF00141.23 OAG34559.1 - 1.8e-23 83.5 0.0 3.1e-23 82.7 0.0 1.3 1 0 0 1 1 1 1 Peroxidase adh_short PF00106.25 OAG34560.1 - 3.3e-32 111.6 0.0 6.4e-21 74.7 0.0 3.1 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAG34560.1 - 8.7e-19 68.0 0.0 4.5e-09 36.2 0.0 3.1 2 1 1 3 3 3 3 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG34560.1 - 8.4e-09 35.6 0.0 1.6e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OAG34560.1 - 0.0025 17.0 0.0 0.0035 16.5 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 OAG34560.1 - 0.097 12.9 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Fungal_trans PF04082.18 OAG34561.1 - 1.7e-09 37.1 0.1 2.8e-09 36.4 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG34561.1 - 3.8e-06 26.9 8.8 6.9e-06 26.1 8.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_6 PF12697.7 OAG34562.1 - 2.7e-08 34.7 2.8 3.3e-08 34.4 2.8 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Fungal_trans PF04082.18 OAG34563.1 - 2.8e-29 102.0 2.7 4.7e-29 101.2 2.7 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 OAG34563.1 - 6e-07 29.6 10.9 0.00055 20.2 0.8 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAG34563.1 - 5.7e-05 23.6 8.0 0.043 14.7 0.3 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OAG34563.1 - 7.8 7.1 15.3 5.7 7.6 3.2 3.4 3 0 0 3 3 3 0 Zinc-finger double domain AIRC PF00731.20 OAG34564.1 - 1.1e-56 190.5 1.3 1.4e-56 190.2 1.3 1.0 1 0 0 1 1 1 1 AIR carboxylase QRPTase_C PF01729.19 OAG34565.1 - 2.4e-54 183.6 0.0 3.7e-54 183.0 0.0 1.3 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 OAG34565.1 - 2.3e-17 62.8 0.1 1.3e-16 60.4 0.1 2.2 1 1 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain PRAI PF00697.22 OAG34565.1 - 0.026 14.3 0.0 0.041 13.7 0.0 1.3 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase MFS_1 PF07690.16 OAG34566.1 - 5e-33 114.5 24.8 7.5e-33 113.9 24.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 OAG34566.1 - 0.0026 16.1 5.8 0.0051 15.2 5.8 1.5 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family zf-RING_6 PF14835.6 OAG34566.1 - 0.079 12.8 0.0 0.51 10.2 0.0 2.2 2 0 0 2 2 2 0 zf-RING of BARD1-type protein SelR PF01641.18 OAG34567.1 - 2e-51 173.1 0.3 2.4e-51 172.9 0.3 1.0 1 0 0 1 1 1 1 SelR domain zinc_ribbon_10 PF10058.9 OAG34567.1 - 0.0029 17.3 0.1 0.2 11.4 0.0 2.2 2 0 0 2 2 2 1 Predicted integral membrane zinc-ribbon metal-binding protein Yippee-Mis18 PF03226.14 OAG34567.1 - 0.027 14.7 0.4 0.077 13.2 0.4 1.8 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Tnp_zf-ribbon_2 PF13842.6 OAG34567.1 - 0.029 15.2 0.2 9.9 7.1 0.1 2.4 2 0 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon TF_Zn_Ribbon PF08271.12 OAG34567.1 - 0.042 13.4 2.9 0.51 9.9 0.3 2.7 3 0 0 3 3 3 0 TFIIB zinc-binding MCM_OB PF17207.3 OAG34567.1 - 0.06 13.2 0.3 0.15 11.9 0.0 1.7 2 0 0 2 2 2 0 MCM OB domain DZR PF12773.7 OAG34567.1 - 0.082 13.0 4.5 1.4 9.0 4.6 2.3 1 1 1 2 2 2 0 Double zinc ribbon Ribosomal_L37e PF01907.19 OAG34567.1 - 0.16 12.2 2.9 4.5 7.5 0.4 2.4 2 0 0 2 2 2 0 Ribosomal protein L37e zf-Mss51 PF13824.6 OAG34567.1 - 0.99 9.6 4.9 5 7.3 0.4 3.2 2 1 1 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-ribbon_3 PF13248.6 OAG34567.1 - 2.1 7.9 5.9 2.4 7.7 0.1 3.0 4 0 0 4 4 4 0 zinc-ribbon domain CUE PF02845.16 OAG34568.1 - 2.8e-06 26.9 0.0 6.7e-06 25.7 0.0 1.7 1 0 0 1 1 1 1 CUE domain DUF1771 PF08590.10 OAG34568.1 - 0.00058 20.2 7.4 0.0019 18.5 7.4 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.21 OAG34568.1 - 0.00079 19.7 0.1 0.0026 18.1 0.1 1.9 1 0 0 1 1 1 1 Smr domain SnoaL_2 PF12680.7 OAG34569.1 - 0.064 13.9 0.0 0.097 13.3 0.0 1.3 1 0 0 1 1 1 0 SnoaL-like domain VHS PF00790.19 OAG34570.1 - 2.3e-18 66.4 0.0 5.3e-18 65.2 0.0 1.6 1 0 0 1 1 1 1 VHS domain GAT PF03127.14 OAG34570.1 - 8.2e-06 26.0 0.3 7.3e-05 23.0 0.1 2.5 2 1 0 2 2 2 1 GAT domain ENTH PF01417.20 OAG34570.1 - 0.00083 19.4 0.0 0.0035 17.4 0.0 2.0 2 1 0 2 2 2 1 ENTH domain Inositol_P PF00459.25 OAG34571.1 - 6e-52 176.8 1.0 2e-51 175.1 1.0 1.6 1 1 0 1 1 1 1 Inositol monophosphatase family Ribosomal_L6 PF00347.23 OAG34572.1 - 2.5e-22 79.4 0.0 3.4e-11 43.7 0.0 2.6 2 1 0 2 2 2 2 Ribosomal protein L6 Pkinase PF00069.25 OAG34573.1 - 6.6e-17 61.7 0.0 4.6e-16 59.0 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG34573.1 - 1.8e-12 47.1 0.0 9e-12 44.8 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Dfp1_Him1_M PF08630.10 OAG34574.1 - 6.2e-33 113.7 0.5 2.8e-32 111.6 0.0 2.3 2 0 0 2 2 2 1 Dfp1/Him1, central region zf-DBF PF07535.12 OAG34574.1 - 9.3e-22 76.9 0.1 1.8e-21 76.0 0.1 1.5 1 0 0 1 1 1 1 DBF zinc finger PTCB-BRCT PF12738.7 OAG34574.1 - 0.018 15.0 0.0 0.045 13.7 0.0 1.7 1 0 0 1 1 1 0 twin BRCT domain BRCT_2 PF16589.5 OAG34574.1 - 0.17 12.3 0.0 0.45 10.9 0.0 1.7 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain rRNA_processing PF08524.11 OAG34574.1 - 0.74 9.8 10.8 2.3 8.2 2.5 2.6 2 0 0 2 2 2 0 rRNA processing Dicty_REP PF05086.12 OAG34574.1 - 2.1 6.2 3.7 3 5.7 3.7 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Pkinase PF00069.25 OAG34575.1 - 1.8e-63 214.4 0.0 2.4e-63 214.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG34575.1 - 1e-35 123.3 0.0 1.4e-35 122.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAG34575.1 - 1.3e-05 24.7 0.0 2e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 OAG34575.1 - 0.00015 21.8 0.5 0.00043 20.3 0.2 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 OAG34575.1 - 0.00072 19.0 0.4 0.0014 18.0 0.4 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OAG34575.1 - 0.0039 16.2 0.0 0.0055 15.7 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Endonuc_Holl PF10107.9 OAG34575.1 - 0.029 14.2 0.1 0.39 10.5 0.0 2.1 2 0 0 2 2 2 0 Endonuclease related to archaeal Holliday junction resolvase Pkinase_fungal PF17667.1 OAG34575.1 - 0.049 12.4 0.0 0.076 11.8 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase MCPVI PF02993.14 OAG34575.1 - 1 9.1 6.4 2.8 7.7 6.6 1.5 2 0 0 2 2 2 0 Minor capsid protein VI SNF2_N PF00176.23 OAG34576.1 - 2.4e-67 227.2 0.2 9.6e-66 221.9 0.2 2.9 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OAG34576.1 - 2.7e-14 53.4 0.0 1.4e-13 51.2 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG34576.1 - 3.9e-10 40.0 0.7 1.8e-09 37.8 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit BUD22 PF09073.10 OAG34576.1 - 0.038 13.3 20.5 0.0083 15.5 10.6 2.4 2 0 0 2 2 2 0 BUD22 DZR PF12773.7 OAG34576.1 - 0.058 13.4 0.8 0.12 12.4 0.8 1.4 1 0 0 1 1 1 0 Double zinc ribbon Nop25 PF09805.9 OAG34576.1 - 0.58 10.6 21.5 5.4 7.5 14.1 2.9 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) Zip PF02535.22 OAG34576.1 - 3.2 6.9 4.5 6.7 5.8 4.5 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter V_ATPase_I PF01496.19 OAG34576.1 - 3.5 5.4 6.1 6.5 4.5 6.1 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FYDLN_acid PF09538.10 OAG34576.1 - 4.1 8.1 30.4 0.75 10.5 19.8 2.8 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Cwf_Cwc_15 PF04889.12 OAG34576.1 - 8.4 6.0 34.4 0.26 11.0 19.0 2.6 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein zf-C2H2_2 PF12756.7 OAG34577.1 - 1.4e-23 83.2 2.5 2.9e-23 82.1 2.5 1.6 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) HEPN_RES_NTD1 PF18870.1 OAG34577.1 - 0.12 12.5 1.3 0.6 10.3 0.0 2.4 3 0 0 3 3 3 0 HEPN/RES N-terminal domain 1 zf-BED PF02892.15 OAG34577.1 - 0.27 11.3 2.2 3.6 7.7 0.0 3.1 3 0 0 3 3 3 0 BED zinc finger F-box PF00646.33 OAG34578.1 - 7.5e-08 32.1 3.2 7.5e-08 32.1 3.2 2.6 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.7 OAG34578.1 - 1.4e-07 31.3 3.2 3.2e-07 30.1 3.2 1.6 1 0 0 1 1 1 1 F-box-like RPEL PF02755.15 OAG34578.1 - 0.00024 20.7 6.1 0.00043 19.9 0.1 3.3 3 1 0 3 3 3 1 RPEL repeat F-box_4 PF15966.5 OAG34578.1 - 0.0029 17.5 2.6 0.0043 16.9 0.7 2.1 2 0 0 2 2 2 1 F-box HemY_N PF07219.13 OAG34578.1 - 0.025 14.8 0.2 0.062 13.5 0.2 1.6 1 0 0 1 1 1 0 HemY protein N-terminus PknG_rubred PF16919.5 OAG34578.1 - 0.06 13.5 5.3 0.06 13.5 3.3 1.9 1 1 1 2 2 2 0 Protein kinase G rubredoxin domain UQ_con PF00179.26 OAG34579.1 - 4.9e-38 129.9 0.1 6e-38 129.6 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 OAG34579.1 - 0.056 13.7 0.1 0.11 12.8 0.0 1.6 2 0 0 2 2 2 0 RWD domain Prok-E2_E PF14462.6 OAG34579.1 - 0.058 13.2 0.0 0.15 11.9 0.0 1.6 2 0 0 2 2 2 0 Prokaryotic E2 family E Pantoate_transf PF02548.15 OAG34580.1 - 5.4e-107 357.0 0.5 6.6e-107 356.7 0.5 1.1 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 OAG34580.1 - 1.6e-07 31.1 1.8 5.5e-07 29.3 1.8 1.9 1 1 0 1 1 1 1 Phosphoenolpyruvate phosphomutase 4HFCP_synth PF04476.13 OAG34580.1 - 0.059 13.1 0.1 0.097 12.4 0.1 1.4 1 0 0 1 1 1 0 4-HFC-P synthase YceG PF02618.16 OAG34580.1 - 0.077 12.5 0.0 0.27 10.7 0.0 1.7 1 1 1 2 2 2 0 YceG-like family NanE PF04131.14 OAG34580.1 - 0.098 11.8 1.6 8.1 5.6 0.1 2.6 3 0 0 3 3 3 0 Putative N-acetylmannosamine-6-phosphate epimerase APG12 PF04110.13 OAG34581.1 - 3.5e-19 69.0 0.0 5e-19 68.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Cytomega_TRL10 PF06084.11 OAG34581.1 - 0.16 12.0 0.1 0.23 11.5 0.1 1.2 1 0 0 1 1 1 0 Cytomegalovirus TRL10 protein Cellulase PF00150.18 OAG34583.1 - 3.2e-13 49.8 0.1 8.4e-13 48.4 0.1 1.7 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF5542 PF17696.1 OAG34583.1 - 8.8e-05 22.6 1.0 0.00021 21.3 0.3 2.1 1 1 0 1 1 1 1 Family of unknown function (DUF5542) Lysis_col PF02402.16 OAG34583.1 - 0.045 13.4 1.1 0.088 12.5 1.1 1.4 1 0 0 1 1 1 0 Lysis protein DUF4407 PF14362.6 OAG34583.1 - 0.11 11.8 0.5 0.19 11.0 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FAD_binding_9 PF08021.11 OAG34583.1 - 0.12 12.6 0.0 0.87 9.8 0.0 2.2 2 0 0 2 2 2 0 Siderophore-interacting FAD-binding domain MASE4 PF17158.4 OAG34583.1 - 0.17 11.2 0.0 0.27 10.4 0.0 1.2 1 0 0 1 1 1 0 Membrane-associated sensor, integral membrane domain TAF1D PF15333.6 OAG34583.1 - 0.24 11.1 11.3 0.47 10.2 11.3 1.4 1 0 0 1 1 1 0 TATA box-binding protein-associated factor 1D DUF1980 PF09323.10 OAG34583.1 - 0.31 10.9 0.0 0.31 10.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) ABC_export PF16962.5 OAG34583.1 - 3.3 6.1 4.6 0.99 7.8 1.7 1.5 1 1 1 2 2 2 0 Putative ABC exporter Csa1 PF06023.12 OAG34584.1 - 0.0057 16.1 0.0 0.01 15.2 0.0 1.4 1 0 0 1 1 1 1 CRISPR-associated exonuclease Csa1 Pyridox_ox_2 PF12900.7 OAG34585.1 - 2.2e-39 134.7 0.0 3.2e-39 134.2 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Peptidase_M24 PF00557.24 OAG34586.1 - 1.8e-50 171.5 0.0 3.1e-50 170.8 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 OAG34586.1 - 9.2e-39 132.0 0.0 1.6e-38 131.2 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Tox-GHH PF15636.6 OAG34586.1 - 0.14 12.2 0.4 0.53 10.3 0.2 2.0 2 0 0 2 2 2 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin SSF PF00474.17 OAG34587.1 - 1.6e-21 76.7 28.6 2.8e-21 75.9 28.6 1.4 1 0 0 1 1 1 1 Sodium:solute symporter family P22_AR_C PF10548.9 OAG34587.1 - 0.19 11.9 0.4 0.46 10.7 0.4 1.6 1 0 0 1 1 1 0 P22AR C-terminal domain LapA_dom PF06305.11 OAG34588.1 - 0.0056 16.5 4.6 0.76 9.6 0.2 2.4 2 0 0 2 2 2 2 Lipopolysaccharide assembly protein A domain F1F0-ATPsyn_F PF10791.9 OAG34588.1 - 0.06 13.8 0.0 0.12 12.9 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial F1-F0 ATP synthase subunit F of fungi SSB PF00436.25 OAG34589.1 - 3.8e-15 55.8 0.0 5e-15 55.4 0.0 1.2 1 0 0 1 1 1 1 Single-strand binding protein family STE3 PF02076.15 OAG34590.1 - 1.6e-72 244.1 11.6 1.9e-72 243.9 11.6 1.0 1 0 0 1 1 1 1 Pheromone A receptor HSBP1 PF06825.12 OAG34591.1 - 0.0097 15.7 0.3 0.14 12.1 0.1 2.3 2 0 0 2 2 2 1 Heat shock factor binding protein 1 Sugarporin_N PF11471.8 OAG34591.1 - 0.035 14.1 2.3 0.056 13.4 0.6 2.3 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension SQS_PSY PF00494.19 OAG34591.1 - 0.036 13.6 3.9 0.068 12.7 3.9 1.4 1 0 0 1 1 1 0 Squalene/phytoene synthase UPF0242 PF06785.11 OAG34591.1 - 0.29 11.2 1.7 0.25 11.4 0.2 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus MerC PF03203.14 OAG34591.1 - 2.6 8.5 4.9 27 5.3 0.6 2.3 2 0 0 2 2 2 0 MerC mercury resistance protein GSH_synth_ATP PF03917.17 OAG34592.1 - 6.1e-134 446.5 0.0 6.9e-134 446.3 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 OAG34592.1 - 4.4e-30 104.2 0.0 7.8e-30 103.4 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic glutathione synthase SNF2_N PF00176.23 OAG34593.1 - 8e-43 146.5 0.4 1.6e-42 145.5 0.4 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OAG34593.1 - 3.9e-19 69.0 0.5 3.6e-17 62.7 0.0 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG34593.1 - 3.4e-07 30.4 0.2 3.4e-06 27.2 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SAM_2 PF07647.17 OAG34593.1 - 1.8e-06 28.0 0.0 4.7e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 OAG34593.1 - 0.00011 22.6 0.0 0.00032 21.1 0.0 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) HIRA_B PF09453.10 OAG34593.1 - 0.0018 18.1 0.5 0.0054 16.5 0.0 2.1 2 0 0 2 2 2 1 HIRA B motif ERCC3_RAD25_C PF16203.5 OAG34593.1 - 0.002 17.4 0.0 0.0045 16.2 0.0 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase SWI2_SNF2 PF18766.1 OAG34593.1 - 0.0024 17.6 0.0 1.5 8.4 0.0 2.5 2 0 0 2 2 2 2 SWI2/SNF2 ATPase LIDHydrolase PF10230.9 OAG34594.1 - 1.2e-54 185.6 0.0 5.2e-44 150.8 0.1 2.4 2 1 0 2 2 2 2 Lipid-droplet associated hydrolase Abhydrolase_6 PF12697.7 OAG34594.1 - 0.00028 21.6 1.2 0.0033 18.1 0.4 2.8 2 1 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG34594.1 - 0.011 15.0 0.3 0.055 12.7 0.0 2.0 2 0 0 2 2 2 0 Serine aminopeptidase, S33 PGAP1 PF07819.13 OAG34594.1 - 0.018 14.8 0.7 0.036 13.8 0.1 1.7 2 0 0 2 2 2 0 PGAP1-like protein Lipase_3 PF01764.25 OAG34594.1 - 0.065 13.1 0.1 0.38 10.6 0.0 2.1 2 0 0 2 2 2 0 Lipase (class 3) DCP1 PF06058.13 OAG34595.1 - 1e-24 86.7 0.0 1.5e-24 86.2 0.0 1.2 1 0 0 1 1 1 1 Dcp1-like decapping family Septin PF00735.18 OAG34596.1 - 5.8e-107 357.1 0.0 1.3e-106 356.1 0.0 1.5 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 OAG34596.1 - 3.4e-05 23.9 0.0 8.7e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 OAG34596.1 - 0.0012 18.9 3.1 1.4 8.9 0.0 3.1 2 1 1 3 3 3 2 Dynamin family RsgA_GTPase PF03193.16 OAG34596.1 - 0.0024 17.8 2.2 0.009 15.9 0.1 2.7 3 1 0 3 3 3 1 RsgA GTPase GTP_EFTU PF00009.27 OAG34596.1 - 0.0039 16.8 0.1 0.31 10.6 0.0 2.4 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 OAG34596.1 - 0.1 12.9 0.8 0.19 12.0 0.1 2.0 2 1 0 2 2 2 0 AAA domain GBP_C PF02841.14 OAG34596.1 - 0.12 11.7 6.3 0.18 11.2 6.3 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Ribosomal_S17e PF00833.18 OAG34596.1 - 0.32 10.9 3.7 0.69 9.8 3.7 1.5 1 0 0 1 1 1 0 Ribosomal S17 EB1 PF03271.17 OAG34596.1 - 0.99 9.7 4.6 5.6 7.3 1.1 2.6 2 0 0 2 2 2 0 EB1-like C-terminal motif Pkinase PF00069.25 OAG34597.1 - 5.4e-53 180.0 0.0 6.7e-53 179.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG34597.1 - 8.5e-28 97.3 1.2 1.5e-26 93.3 1.2 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAG34597.1 - 0.0063 15.3 1.1 0.078 11.7 0.1 2.1 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 OAG34597.1 - 0.02 14.2 0.0 0.044 13.1 0.0 1.5 1 0 0 1 1 1 0 Kinase-like FTA2 PF13095.6 OAG34597.1 - 0.2 11.2 0.7 1.2 8.7 0.0 2.0 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Y_phosphatase3 PF13350.6 OAG34598.1 - 1.3e-48 166.0 0.0 1.9e-48 165.5 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 OAG34598.1 - 0.00067 19.3 0.0 0.0013 18.4 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 OAG34598.1 - 0.021 14.4 0.0 0.032 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DLIC PF05783.11 OAG34599.1 - 8.1e-32 110.7 0.0 8.1e-32 110.7 0.0 2.9 2 1 0 3 3 3 1 Dynein light intermediate chain (DLIC) Utp12 PF04003.12 OAG34599.1 - 0.11 12.9 0.3 0.23 11.8 0.1 1.7 2 0 0 2 2 2 0 Dip2/Utp12 Family RRM_1 PF00076.22 OAG34600.1 - 1.1e-15 57.2 0.0 2.2e-15 56.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OAG34600.1 - 0.045 13.3 0.0 0.07 12.7 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OAG34600.1 - 0.085 13.0 0.0 0.2 11.8 0.0 1.7 1 1 0 1 1 1 0 RNA recognition motif AMP-binding PF00501.28 OAG34601.1 - 1.3e-96 323.8 0.0 1.5e-96 323.6 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG34601.1 - 1.2e-20 74.2 0.1 3.1e-20 72.9 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF2052 PF09747.9 OAG34603.1 - 2.2e-18 67.1 16.5 1.2e-15 58.2 9.7 2.9 1 1 1 2 2 2 2 Coiled-coil domain containing protein (DUF2052) PG_binding_1 PF01471.18 OAG34603.1 - 0.031 14.5 0.0 0.069 13.4 0.0 1.6 1 0 0 1 1 1 0 Putative peptidoglycan binding domain ThiF PF00899.21 OAG34605.1 - 6e-34 117.5 0.0 7.8e-34 117.1 0.0 1.1 1 0 0 1 1 1 1 ThiF family Rit1_C PF17184.4 OAG34606.1 - 1.3e-91 306.8 0.0 1.9e-91 306.3 0.0 1.2 1 0 0 1 1 1 1 Rit1 N-terminal domain Aldo_ket_red PF00248.21 OAG34606.1 - 2.3e-45 155.0 0.0 2.5e-43 148.4 0.0 2.1 1 1 0 1 1 1 1 Aldo/keto reductase family Init_tRNA_PT PF04179.12 OAG34606.1 - 3.1e-17 62.9 0.3 6.2e-17 61.9 0.3 1.5 1 0 0 1 1 1 1 Rit1 DUSP-like domain P3A PF08727.11 OAG34606.1 - 1.5 8.3 6.4 3 7.3 0.2 2.9 3 0 0 3 3 3 0 Poliovirus 3A protein like Pro_CA PF00484.19 OAG34607.1 - 4.3e-09 36.8 0.2 8.4e-09 35.9 0.2 1.6 1 1 0 1 1 1 1 Carbonic anhydrase EVI2A PF05399.11 OAG34608.1 - 0.045 13.3 1.0 0.077 12.6 1.0 1.3 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) PLA2_B PF01735.18 OAG34609.1 - 1e-15 57.1 0.4 4.1e-07 28.8 0.0 2.2 2 0 0 2 2 2 2 Lysophospholipase catalytic domain F-protein PF00469.20 OAG34609.1 - 0.095 12.3 0.2 0.24 11.0 0.2 1.6 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef Zn_clus PF00172.18 OAG34610.1 - 0.00011 22.3 13.6 0.00022 21.3 13.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cdc6_C PF09079.11 OAG34610.1 - 0.055 13.5 0.1 0.16 12.0 0.0 1.9 2 0 0 2 2 2 0 CDC6, C terminal winged helix domain NYD-SP28_assoc PF14775.6 OAG34610.1 - 0.27 11.4 1.0 0.57 10.3 1.0 1.5 1 0 0 1 1 1 0 Sperm tail C-terminal domain Mucin PF01456.17 OAG34611.1 - 0.014 15.4 18.1 0.021 14.8 18.1 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF908 PF06012.12 OAG34611.1 - 0.26 10.7 1.7 0.28 10.6 1.7 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Podoplanin PF05808.11 OAG34612.1 - 3.7e-05 23.9 0.1 6e-05 23.2 0.1 1.3 1 0 0 1 1 1 1 Podoplanin SKG6 PF08693.10 OAG34612.1 - 0.00015 21.1 2.2 0.00032 20.0 2.2 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4690 PF15756.5 OAG34612.1 - 0.00047 20.7 0.2 0.0012 19.5 0.2 1.7 1 0 0 1 1 1 1 Small Novel Rich in Cartilage Amnionless PF14828.6 OAG34612.1 - 0.0023 16.8 0.0 0.0068 15.3 0.0 1.6 2 0 0 2 2 2 1 Amnionless VSP PF03302.13 OAG34612.1 - 0.003 16.5 0.2 0.0041 16.0 0.2 1.2 1 0 0 1 1 1 1 Giardia variant-specific surface protein EphA2_TM PF14575.6 OAG34612.1 - 0.014 16.2 0.0 0.026 15.4 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain LapA_dom PF06305.11 OAG34612.1 - 0.03 14.1 1.2 0.062 13.1 1.2 1.5 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain DUF4448 PF14610.6 OAG34612.1 - 0.041 13.7 0.0 0.066 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) CYYR1 PF10873.8 OAG34612.1 - 0.05 14.1 0.3 0.12 12.8 0.0 1.8 2 0 0 2 2 2 0 Cysteine and tyrosine-rich protein 1 DUF5305 PF17231.2 OAG34612.1 - 0.1 12.0 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Mid2 PF04478.12 OAG34612.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Adeno_E3_CR2 PF02439.15 OAG34612.1 - 0.18 11.6 0.3 0.45 10.3 0.3 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Syndecan PF01034.20 OAG34612.1 - 3.2 7.7 5.0 0.34 10.8 0.5 1.6 2 0 0 2 2 1 0 Syndecan domain Asp_Glu_race PF01177.22 OAG34613.1 - 1.8e-39 135.9 0.0 2.1e-39 135.7 0.0 1.1 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase Oxidored_nitro PF00148.19 OAG34613.1 - 0.029 13.1 0.1 0.14 10.9 0.1 2.0 1 1 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase Glyco_transf_25 PF01755.17 OAG34614.1 - 5.2e-05 23.2 0.0 0.15 11.9 0.0 2.1 2 0 0 2 2 2 2 Glycosyltransferase family 25 (LPS biosynthesis protein) Cutinase PF01083.22 OAG34614.1 - 0.1 12.6 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 Cutinase motB PF17613.2 OAG34614.1 - 0.15 11.9 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 Modifier of transcription adh_short PF00106.25 OAG34615.1 - 6.6e-34 117.1 0.0 1.1e-33 116.4 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG34615.1 - 5.7e-19 68.6 0.0 1.3e-18 67.4 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG34615.1 - 9.6e-06 25.6 0.0 2.4e-05 24.4 0.0 1.6 1 1 0 1 1 1 1 KR domain TrkA_N PF02254.18 OAG34615.1 - 0.16 12.3 0.0 0.33 11.2 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain DUF420 PF04238.12 OAG34616.1 - 1 9.7 10.9 0.15 12.3 0.5 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF420) AA_permease_2 PF13520.6 OAG34617.1 - 6.1e-60 203.2 45.0 8.2e-60 202.8 45.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAG34617.1 - 1.7e-25 89.6 39.1 2.3e-25 89.2 39.1 1.0 1 0 0 1 1 1 1 Amino acid permease TMEM220 PF15071.6 OAG34617.1 - 3 8.7 8.5 0.29 11.9 0.8 3.1 3 0 0 3 3 3 0 Transmembrane family 220, helix DUF2462 PF09495.10 OAG34618.1 - 5.5e-22 78.3 11.5 5.5e-22 78.3 11.5 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF2462) DUF3251 PF11622.8 OAG34618.1 - 0.12 12.0 0.7 0.15 11.7 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3251) DUF5427 PF10310.9 OAG34619.1 - 3.2e-172 573.7 0.2 3.9e-172 573.4 0.2 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5427) Flu_M1_C PF08289.11 OAG34619.1 - 0.062 13.5 0.1 0.19 12.0 0.1 1.8 1 0 0 1 1 1 0 Influenza Matrix protein (M1) C-terminal domain CDC27 PF09507.10 OAG34619.1 - 2.5 7.4 12.1 4.9 6.4 12.1 1.5 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 SPX PF03105.19 OAG34619.1 - 9.1 6.1 12.1 16 5.3 12.1 1.4 1 0 0 1 1 1 0 SPX domain THUMP PF02926.17 OAG34622.1 - 7.6e-09 35.8 0.2 1.9e-08 34.5 0.2 1.7 1 1 0 1 1 1 1 THUMP domain MPS2 PF17060.5 OAG34623.1 - 0.0047 16.2 1.0 0.0047 16.2 1.0 2.0 2 0 0 2 2 2 1 Monopolar spindle protein 2 Spc7 PF08317.11 OAG34623.1 - 0.022 13.6 18.7 0.013 14.4 1.4 3.1 2 1 1 3 3 3 0 Spc7 kinetochore protein HsbA PF12296.8 OAG34623.1 - 0.058 13.8 0.1 4 7.9 0.0 2.8 2 0 0 2 2 2 0 Hydrophobic surface binding protein A PKcGMP_CC PF16808.5 OAG34623.1 - 0.069 13.0 4.9 1.8 8.5 0.2 3.4 2 1 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase SOAR PF16533.5 OAG34623.1 - 0.11 12.5 7.1 1.5 8.9 0.7 2.9 2 1 0 2 2 2 0 STIM1 Orai1-activating region Cauli_AT PF03233.13 OAG34623.1 - 0.15 12.0 2.8 1.6 8.7 0.4 2.8 2 1 1 3 3 3 0 Aphid transmission protein Tropomyosin_1 PF12718.7 OAG34623.1 - 0.45 10.7 22.5 0.065 13.4 1.3 3.6 2 1 1 3 3 3 0 Tropomyosin like Fib_alpha PF08702.10 OAG34623.1 - 0.45 10.7 11.1 0.66 10.2 0.2 3.3 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Med9 PF07544.13 OAG34623.1 - 0.62 10.2 12.1 22 5.2 1.1 4.1 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 V_ATPase_I PF01496.19 OAG34623.1 - 0.77 7.6 10.7 2.5 5.9 0.5 2.2 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family UPF0242 PF06785.11 OAG34623.1 - 0.85 9.7 17.9 4.5 7.3 1.1 2.5 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus TPR_MLP1_2 PF07926.12 OAG34623.1 - 0.88 9.6 24.5 0.43 10.7 10.1 3.3 3 1 0 3 3 2 0 TPR/MLP1/MLP2-like protein zf-C4H2 PF10146.9 OAG34623.1 - 1.3 9.3 10.2 2.1 8.6 3.2 2.6 2 0 0 2 2 2 0 Zinc finger-containing protein DUF641 PF04859.12 OAG34623.1 - 1.8 8.9 13.8 0.6 10.5 2.3 3.1 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) Prominin PF05478.11 OAG34623.1 - 2.5 5.9 11.7 0.044 11.8 2.3 2.1 1 1 0 2 2 2 0 Prominin Csm1_N PF18504.1 OAG34623.1 - 2.8 8.3 19.8 5.2 7.5 0.2 4.1 3 1 1 4 4 4 0 Csm1 N-terminal domain Cdh1_DBD_1 PF18196.1 OAG34623.1 - 2.9 8.2 11.5 0.38 11.1 2.1 3.2 2 1 1 3 3 3 0 Chromodomain helicase DNA-binding domain 1 CC2-LZ PF16516.5 OAG34623.1 - 3.2 8.2 15.5 0.42 11.0 1.8 3.9 2 1 1 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator FAM76 PF16046.5 OAG34623.1 - 3.3 7.0 12.2 0.29 10.4 0.6 2.8 2 1 0 2 2 2 0 FAM76 protein Phage_GP20 PF06810.11 OAG34623.1 - 4.5 7.1 7.7 14 5.4 1.0 2.7 2 1 0 2 2 2 0 Phage minor structural protein GP20 DUF3552 PF12072.8 OAG34623.1 - 4.9 6.5 20.9 5.6 6.3 5.0 3.2 2 1 0 3 3 3 0 Domain of unknown function (DUF3552) Uso1_p115_C PF04871.13 OAG34623.1 - 5.1 7.5 17.5 8.5 6.8 1.2 3.6 2 1 1 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region Spectrin PF00435.21 OAG34623.1 - 6.8 7.2 12.4 11 6.6 1.3 3.6 2 1 1 3 3 3 0 Spectrin repeat DUF883 PF05957.13 OAG34623.1 - 9.8 6.9 17.6 0.096 13.3 1.7 4.2 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF883) GFO_IDH_MocA PF01408.22 OAG34624.1 - 2.9e-13 50.7 0.0 4.4e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Ribonuclease_T2 PF00445.18 OAG34625.1 - 3.4e-37 128.4 0.1 8.3e-37 127.2 0.0 1.6 2 0 0 2 2 2 1 Ribonuclease T2 family MutS_V PF00488.21 OAG34628.1 - 6.8e-76 254.5 0.3 2.1e-75 252.9 0.1 2.0 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.18 OAG34628.1 - 8.2e-38 130.6 1.1 8.2e-38 130.6 1.1 2.0 2 0 0 2 2 2 1 MutS domain III MutS_II PF05188.17 OAG34628.1 - 2.2e-21 76.6 1.7 1.6e-20 73.8 0.0 3.0 2 1 1 3 3 3 1 MutS domain II MutS_IV PF05190.18 OAG34628.1 - 1.5e-18 66.9 1.2 6.3e-18 64.9 1.2 2.1 1 0 0 1 1 1 1 MutS family domain IV MutS_I PF01624.20 OAG34628.1 - 7.6e-16 58.4 0.0 2.1e-14 53.7 0.0 3.0 2 1 1 3 3 3 1 MutS domain I AAA_27 PF13514.6 OAG34628.1 - 0.021 14.4 0.1 0.08 12.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 OAG34628.1 - 0.12 12.3 0.3 3.2 7.6 0.0 2.7 2 0 0 2 2 2 0 Rad17 P-loop domain DUF2183 PF09949.9 OAG34629.1 - 1.2e-35 121.8 0.1 5e-35 119.8 0.0 2.1 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2183) B PF02216.16 OAG34629.1 - 0.2 11.6 0.1 0.47 10.5 0.0 1.6 2 0 0 2 2 2 0 B domain Aa_trans PF01490.18 OAG34630.1 - 1.6e-23 83.1 32.3 3.1e-23 82.2 32.3 1.4 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein DUF2157 PF09925.9 OAG34630.1 - 1.8 8.4 9.1 0.067 13.0 2.3 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2157) Glyco_hydro_76 PF03663.14 OAG34631.1 - 3.3e-139 464.5 18.9 4.6e-139 464.0 18.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 CSN8_PSD8_EIF3K PF10075.9 OAG34631.1 - 3.5e-41 140.6 0.0 5.6e-41 139.9 0.0 1.3 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family F-box-like PF12937.7 OAG34632.1 - 3.4e-16 58.8 0.6 4.1e-15 55.4 0.1 2.7 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 OAG34632.1 - 4.7e-08 32.7 0.4 1.6e-07 31.0 0.4 2.0 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 OAG34632.1 - 0.00034 20.5 0.0 0.00097 19.0 0.0 1.8 1 0 0 1 1 1 1 F-box LRR_1 PF00560.33 OAG34632.1 - 5.1 8.0 5.1 18 6.3 0.2 4.2 5 1 0 5 5 5 0 Leucine Rich Repeat MFS_1 PF07690.16 OAG34633.1 - 1.3e-28 100.0 40.4 1.3e-28 100.0 40.4 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sad1_UNC PF07738.13 OAG34636.1 - 2.5e-09 37.3 0.0 1.4e-07 31.6 0.0 2.4 1 1 0 1 1 1 1 Sad1 / UNC-like C-terminal Baculo_PEP_C PF04513.12 OAG34636.1 - 0.045 13.8 7.7 0.1 12.7 0.9 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1640 PF07798.11 OAG34636.1 - 0.096 12.7 3.7 0.56 10.2 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) DUF4407 PF14362.6 OAG34636.1 - 2 7.7 4.5 32 3.8 2.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) FlxA PF14282.6 OAG34636.1 - 2.7 8.1 14.6 17 5.5 0.1 3.1 2 1 1 3 3 3 0 FlxA-like protein PI31_Prot_N PF11566.8 OAG34637.1 - 6.3e-50 169.2 0.0 8.4e-50 168.8 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.11 OAG34637.1 - 6e-18 65.8 17.7 6e-18 65.8 17.7 2.9 2 1 0 2 2 2 1 PI31 proteasome regulator Metallophos PF00149.28 OAG34638.1 - 5.4e-38 131.5 0.4 8.6e-38 130.9 0.4 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 OAG34638.1 - 0.094 13.2 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain MatE PF01554.18 OAG34639.1 - 1.6e-56 190.4 16.1 1.3e-30 106.2 3.8 2.4 2 1 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 OAG34639.1 - 0.00019 21.5 6.5 0.00019 21.5 6.5 3.8 4 0 0 4 4 4 1 Polysaccharide biosynthesis C-terminal domain Tti2 PF10521.9 OAG34640.1 - 2.5e-58 197.9 1.4 3.5e-58 197.4 1.4 1.2 1 0 0 1 1 1 1 Tti2 family Ipi1_N PF12333.8 OAG34640.1 - 0.087 13.4 0.0 0.25 11.9 0.0 1.7 1 0 0 1 1 1 0 Rix1 complex component involved in 60S ribosome maturation PglZ PF08665.12 OAG34640.1 - 0.091 12.8 0.0 3.1 7.9 0.0 2.4 2 0 0 2 2 2 0 PglZ domain Syja_N PF02383.18 OAG34641.1 - 1.8e-78 264.1 0.2 3.6e-78 263.1 0.2 1.5 1 0 0 1 1 1 1 SacI homology domain Acyl-CoA_dh_1 PF00441.24 OAG34642.1 - 1e-28 100.4 0.0 1.5e-28 99.9 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 OAG34642.1 - 1.2e-28 100.0 0.3 2.8e-28 98.8 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 OAG34642.1 - 3.3e-23 81.7 0.0 6.2e-23 80.8 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 OAG34642.1 - 2.7e-07 30.9 0.0 5.2e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain PolyA_pol PF01743.20 OAG34643.1 - 1.5e-24 86.8 1.3 5e-24 85.1 1.3 1.9 1 1 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 OAG34643.1 - 0.00015 21.5 0.0 0.00039 20.1 0.0 1.8 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A DUF349 PF03993.12 OAG34643.1 - 0.33 11.3 2.2 6.7 7.1 0.1 2.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) CoaE PF01121.20 OAG34644.1 - 9.8e-39 132.9 0.0 1.2e-20 73.9 0.0 2.1 2 0 0 2 2 2 2 Dephospho-CoA kinase AAA_18 PF13238.6 OAG34644.1 - 0.017 15.6 0.1 0.74 10.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain bZIP_1 PF00170.21 OAG34645.1 - 0.11 12.6 5.2 0.16 12.1 5.2 1.2 1 0 0 1 1 1 0 bZIP transcription factor bZIP_2 PF07716.15 OAG34645.1 - 1.4 9.0 6.8 2.2 8.5 6.8 1.2 1 0 0 1 1 1 0 Basic region leucine zipper Glyco_hydro_17 PF00332.18 OAG34646.1 - 8.5e-16 58.4 1.1 1.1e-15 58.0 1.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 Glyco_hydro_47 PF01532.20 OAG34647.1 - 5.9e-173 576.0 0.0 6.7e-173 575.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Gryzun-like PF12742.7 OAG34647.1 - 0.12 12.3 0.2 0.26 11.3 0.2 1.5 1 0 0 1 1 1 0 Gryzun, putative Golgi trafficking RRM_1 PF00076.22 OAG34648.1 - 0.0011 18.7 0.0 0.0056 16.5 0.0 2.1 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ECH_2 PF16113.5 OAG34649.1 - 3.4e-130 434.4 0.0 4.4e-130 434.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 OAG34649.1 - 7.3e-28 97.5 0.1 1.9e-27 96.2 0.0 1.6 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase KfrA_N PF11740.8 OAG34649.1 - 0.055 14.1 1.3 1.6 9.4 0.1 2.8 3 0 0 3 3 3 0 Plasmid replication region DNA-binding N-term DASH_Dad3 PF08656.10 OAG34649.1 - 0.25 11.4 1.3 5.3 7.2 0.2 2.8 2 1 0 2 2 2 0 DASH complex subunit Dad3 NMD3 PF04981.13 OAG34650.1 - 3e-81 272.5 3.5 4.3e-81 272.0 3.5 1.2 1 0 0 1 1 1 1 NMD3 family DZR PF12773.7 OAG34650.1 - 0.12 12.4 4.7 1.7 8.7 2.9 2.6 2 0 0 2 2 2 0 Double zinc ribbon DUF35_N PF12172.8 OAG34650.1 - 8.6 6.4 7.4 14 5.7 0.1 2.8 3 0 0 3 3 3 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Pkinase PF00069.25 OAG34651.1 - 1.3e-35 123.0 0.0 4e-22 78.8 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAG34651.1 - 1.9e-13 50.3 0.0 4.6e-06 26.1 0.0 2.4 2 1 0 2 2 2 2 Protein tyrosine kinase bZIP_1 PF00170.21 OAG34653.1 - 6.4e-07 29.4 12.2 1.2e-06 28.6 12.2 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 OAG34653.1 - 0.0021 18.1 12.0 0.0047 17.0 12.0 1.6 1 0 0 1 1 1 1 Basic region leucine zipper Ndc1_Nup PF09531.10 OAG34653.1 - 0.071 11.8 10.9 0.092 11.4 10.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SOBP PF15279.6 OAG34653.1 - 0.25 11.9 9.3 0.34 11.5 9.3 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein 3HCDH_N PF02737.18 OAG34653.1 - 1 9.2 3.4 1.5 8.6 3.4 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain bZIP_Maf PF03131.17 OAG34653.1 - 3.3 8.3 16.7 0.13 12.8 9.0 2.5 3 1 1 4 4 4 0 bZIP Maf transcription factor UBA_4 PF14555.6 OAG34654.1 - 0.0059 16.4 0.1 0.012 15.4 0.1 1.5 1 0 0 1 1 1 1 UBA-like domain Dynamin_N PF00350.23 OAG34655.1 - 5.8e-31 107.8 0.0 2.5e-30 105.7 0.0 2.1 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.20 OAG34655.1 - 1.3e-18 67.2 0.0 2.2e-18 66.5 0.0 1.3 1 0 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.23 OAG34655.1 - 6.2e-06 26.3 0.1 0.0001 22.4 0.1 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_21 PF13304.6 OAG34655.1 - 0.012 15.4 0.0 0.037 13.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 OAG34655.1 - 0.013 16.0 1.0 6.3 7.2 0.6 2.8 3 0 0 3 3 3 0 AAA domain AAA_15 PF13175.6 OAG34655.1 - 0.025 14.3 0.8 0.094 12.4 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain LXG PF04740.12 OAG34655.1 - 0.32 10.7 6.6 2.2 7.9 1.1 3.3 4 0 0 4 4 4 0 LXG domain of WXG superfamily KfrA_N PF11740.8 OAG34655.1 - 1.5 9.5 8.3 0.56 10.9 3.0 2.6 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term Pex2_Pex12 PF04757.14 OAG34656.1 - 2.9e-48 164.4 1.0 3.9e-48 164.0 1.0 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_2 PF13639.6 OAG34656.1 - 0.0024 18.2 1.0 0.0044 17.3 1.0 1.4 1 0 0 1 1 1 1 Ring finger domain CDC45 PF02724.14 OAG34656.1 - 0.34 9.2 0.5 0.47 8.7 0.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Ank_2 PF12796.7 OAG34657.1 - 2.6e-50 168.9 2.3 8.1e-13 48.8 0.0 5.1 2 1 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAG34657.1 - 3.9e-40 135.7 5.2 7.7e-08 32.7 0.0 8.1 3 1 6 9 9 9 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG34657.1 - 3.2e-39 128.4 1.9 0.00038 20.7 0.0 12.1 12 0 0 12 12 11 7 Ankyrin repeat Ank PF00023.30 OAG34657.1 - 2.7e-36 122.4 1.2 4.8e-05 23.6 0.0 11.5 11 0 0 11 11 11 8 Ankyrin repeat Ank_5 PF13857.6 OAG34657.1 - 6.6e-20 70.9 10.0 8.1e-05 22.8 0.0 8.2 4 3 4 8 8 8 5 Ankyrin repeats (many copies) NACHT PF05729.12 OAG34657.1 - 8.4e-11 42.1 0.1 2.4e-10 40.6 0.1 1.8 1 0 0 1 1 1 1 NACHT domain Helo_like_N PF17111.5 OAG34657.1 - 8.6e-09 35.1 0.2 1.9e-08 33.9 0.2 1.6 1 1 0 1 1 1 1 Fungal N-terminal domain of STAND proteins AAA_16 PF13191.6 OAG34657.1 - 3.7e-06 27.4 0.1 3.7e-06 27.4 0.1 2.6 3 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 OAG34657.1 - 0.00019 21.7 0.0 0.00067 19.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 OAG34657.1 - 0.058 13.4 0.0 0.18 11.8 0.0 1.9 1 1 0 1 1 1 0 AAA domain T2SSF PF00482.23 OAG34657.1 - 0.089 12.8 2.2 6.3 6.8 0.0 3.9 4 0 0 4 4 4 0 Type II secretion system (T2SS), protein F ATP_bind_1 PF03029.17 OAG34657.1 - 0.096 12.4 0.1 1.1 9.0 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.22 OAG34657.1 - 0.2 12.1 0.0 0.4 11.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase FMO-like PF00743.19 OAG34658.1 - 6.2e-33 114.0 0.0 5.3e-31 107.6 0.0 2.3 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 OAG34658.1 - 4.1e-19 68.9 0.0 9e-17 61.2 0.0 2.1 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG34658.1 - 2.2e-17 63.3 0.0 3.4e-16 59.4 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG34658.1 - 2.6e-16 59.7 0.1 2.1e-14 53.4 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 OAG34658.1 - 1.3e-07 31.7 0.0 8.8e-06 25.9 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 OAG34658.1 - 1.4e-05 25.6 1.0 0.16 12.6 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAG34658.1 - 8e-05 22.7 0.6 0.028 14.4 0.0 3.1 3 1 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.24 OAG34658.1 - 0.0002 21.1 1.0 0.066 12.8 1.0 3.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 OAG34658.1 - 0.00069 19.0 2.5 0.023 14.0 0.4 2.3 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 OAG34658.1 - 0.00085 18.1 1.1 0.028 13.1 0.4 2.7 3 0 0 3 3 3 1 HI0933-like protein FAD_oxidored PF12831.7 OAG34658.1 - 0.00091 18.7 0.0 0.00091 18.7 0.0 1.6 2 0 0 2 2 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 OAG34658.1 - 0.0013 18.0 0.7 0.048 12.9 0.3 2.5 3 0 0 3 3 3 1 Thi4 family NAD_binding_7 PF13241.6 OAG34658.1 - 0.11 13.0 0.0 4.9 7.7 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding Shikimate_DH PF01488.20 OAG34658.1 - 0.38 10.8 1.1 20 5.2 0.1 2.9 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.24 OAG34658.1 - 0.46 9.5 4.5 1.2 8.1 0.7 2.4 2 1 1 3 3 3 0 FAD binding domain zf-C2H2 PF00096.26 OAG34659.1 - 0.029 14.8 1.1 0.065 13.7 1.1 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type Cyt-b5 PF00173.28 OAG34659.1 - 0.17 12.0 0.0 0.35 11.0 0.0 1.4 1 0 0 1 1 1 0 Cytochrome b5-like Heme/Steroid binding domain zf-C2H2 PF00096.26 OAG34660.1 - 2.9e-06 27.4 9.0 0.41 11.2 0.0 3.7 3 1 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_aberr PF17017.5 OAG34660.1 - 0.00022 21.4 0.3 0.012 15.8 0.1 2.3 2 0 0 2 2 2 1 Aberrant zinc-finger Transpos_assoc PF13963.6 OAG34660.1 - 0.066 13.5 4.1 1.3 9.4 0.1 2.4 1 1 1 2 2 2 0 Transposase-associated domain zf-C2H2_4 PF13894.6 OAG34660.1 - 0.068 14.1 9.9 16 6.7 3.5 3.7 3 1 0 3 3 3 0 C2H2-type zinc finger DUF913 PF06025.12 OAG34660.1 - 0.23 10.4 0.0 0.51 9.3 0.0 1.6 1 1 1 2 2 2 0 Domain of Unknown Function (DUF913) DUF2868 PF11067.8 OAG34660.1 - 10 5.6 5.9 14 5.1 5.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2868) Homeodomain PF00046.29 OAG34662.1 - 4.1e-13 49.0 0.3 7.3e-13 48.2 0.3 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 OAG34662.1 - 0.013 15.4 0.0 0.031 14.2 0.0 1.6 1 0 0 1 1 1 0 Homeobox KN domain BLM10_mid PF16507.5 OAG34663.1 - 2.6e-61 207.9 0.0 5e-61 206.9 0.0 1.5 1 1 0 1 1 1 1 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 OAG34663.1 - 6.3e-07 29.2 3.5 1.1e-06 28.4 0.4 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF3437) BLM10_N PF16547.5 OAG34663.1 - 0.004 17.4 0.0 0.011 16.1 0.0 1.6 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, N-terminal Importin_rep_5 PF18816.1 OAG34663.1 - 0.03 14.6 0.0 0.1 13.0 0.0 2.0 1 0 0 1 1 1 0 Importin repeat RT_RNaseH PF17917.1 OAG34665.1 - 0.0048 17.2 0.0 0.0073 16.6 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 OAG34665.1 - 0.0062 16.6 0.0 0.01 15.9 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-C2H2 PF00096.26 OAG34669.1 - 0.0018 18.6 1.1 0.0018 18.6 1.1 4.0 4 0 0 4 4 4 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAG34669.1 - 0.016 16.0 0.8 0.016 16.0 0.8 4.0 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_6 PF13912.6 OAG34669.1 - 0.049 13.7 0.3 0.049 13.7 0.3 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger SSP160 PF06933.11 OAG34670.1 - 0.41 8.8 21.1 0.54 8.4 21.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF3439 PF11921.8 OAG34670.1 - 1.5 8.8 21.4 3.4 7.6 21.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Fez1 PF06818.15 OAG34670.1 - 2.3 8.6 10.2 0.04 14.4 2.2 2.1 2 1 0 2 2 2 0 Fez1 FSA_C PF10479.9 OAG34670.1 - 3.9 5.5 10.3 5 5.1 10.3 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Dicty_REP PF05086.12 OAG34670.1 - 6.4 4.6 18.2 4.1 5.3 16.8 1.3 1 1 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF2420 PF10336.9 OAG34671.1 - 7.8e-17 61.3 0.0 1.5e-16 60.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) FTR1 PF03239.14 OAG34672.1 - 3.4e-86 289.2 6.6 4e-86 289.0 6.6 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family DUF4231 PF14015.6 OAG34672.1 - 0.075 13.5 1.2 0.46 11.0 1.2 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4231) DUF1980 PF09323.10 OAG34672.1 - 1.2 9.0 2.6 4.7 7.1 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF1980) Cu-oxidase_2 PF07731.14 OAG34673.1 - 8e-46 155.2 6.6 3.5e-39 133.7 0.7 3.9 3 1 0 3 3 3 3 Multicopper oxidase Cu-oxidase_3 PF07732.15 OAG34673.1 - 5.2e-43 145.8 0.6 2.6e-41 140.4 1.0 2.8 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.22 OAG34673.1 - 7.8e-36 123.6 0.1 1.2e-34 119.7 0.0 2.3 2 0 0 2 2 2 1 Multicopper oxidase Cupredoxin_1 PF13473.6 OAG34673.1 - 0.18 11.9 0.0 20 5.4 0.0 3.2 3 0 0 3 3 3 0 Cupredoxin-like domain Nucleos_tra2_C PF07662.13 OAG34674.1 - 3.4e-75 252.4 2.1 3.4e-75 252.4 2.1 2.4 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 OAG34674.1 - 6.3e-25 87.6 2.5 6.3e-25 87.6 2.5 2.8 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.14 OAG34674.1 - 0.047 14.0 11.2 0.052 13.8 6.9 3.1 2 1 0 2 2 2 0 Nucleoside recognition DUF155 PF02582.14 OAG34675.1 - 2.2e-52 177.7 0.1 3.6e-52 177.0 0.1 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Mpv17_PMP22 PF04117.12 OAG34676.1 - 6.4e-14 51.9 0.9 6.4e-14 51.9 0.9 1.7 2 0 0 2 2 2 1 Mpv17 / PMP22 family F-box-like PF12937.7 OAG34678.1 - 1.1e-10 41.2 0.6 2.5e-10 40.1 0.6 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAG34678.1 - 9.4e-07 28.6 0.2 2.6e-06 27.2 0.2 1.8 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 OAG34678.1 - 0.029 14.2 0.1 0.11 12.4 0.0 2.0 2 0 0 2 2 2 0 F-box Elongin_A PF06881.11 OAG34678.1 - 0.3 11.6 0.1 0.3 11.6 0.1 2.3 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Tyrosinase PF00264.20 OAG34679.1 - 8.1e-42 144.0 0.5 9.7e-42 143.7 0.5 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase Ran_BP1 PF00638.18 OAG34680.1 - 1.2e-12 48.1 0.0 2.6e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 RanBP1 domain NUP50 PF08911.11 OAG34680.1 - 4.1e-05 24.2 2.8 4.1e-05 24.2 2.8 8.4 9 2 0 9 9 9 1 NUP50 (Nucleoporin 50 kDa) AMIN PF11741.8 OAG34680.1 - 0.013 15.6 0.2 0.14 12.3 0.1 2.3 1 1 1 2 2 2 0 AMIN domain AAA_21 PF13304.6 OAG34680.1 - 0.046 13.5 0.1 0.1 12.4 0.1 1.5 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Ribosomal_L31e PF01198.19 OAG34681.1 - 2.3e-37 127.1 0.2 4.3e-37 126.2 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein L31e CN_hydrolase PF00795.22 OAG34682.1 - 1.3e-59 201.7 0.0 1.5e-59 201.5 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Fungal_trans_2 PF11951.8 OAG34684.1 - 0.0045 15.8 0.0 0.009 14.9 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Methyltransf_23 PF13489.6 OAG34685.1 - 2.3e-11 43.8 0.0 5.3e-07 29.6 0.0 2.3 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 OAG34685.1 - 2.7e-05 24.8 0.0 0.00017 22.3 0.0 2.1 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.17 OAG34685.1 - 0.0027 17.2 0.0 0.0056 16.2 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.13 OAG34685.1 - 0.0036 16.8 0.0 0.0055 16.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 OAG34685.1 - 0.004 17.0 0.0 0.025 14.4 0.0 2.0 1 1 1 2 2 2 1 Methyltransferase domain MTS PF05175.14 OAG34685.1 - 0.011 15.2 0.0 0.025 14.1 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase small domain FtsJ PF01728.19 OAG34685.1 - 0.015 15.4 0.0 0.026 14.7 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_12 PF08242.12 OAG34685.1 - 0.035 14.8 0.0 0.2 12.4 0.0 2.1 1 1 1 2 2 2 0 Methyltransferase domain Methyltransf_16 PF10294.9 OAG34685.1 - 0.046 13.5 0.0 0.08 12.7 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_11 PF08241.12 OAG34685.1 - 0.076 13.7 0.0 0.47 11.1 0.0 2.1 1 1 1 2 2 2 0 Methyltransferase domain Sugar_tr PF00083.24 OAG34686.1 - 3.6e-71 240.4 18.3 2.9e-65 220.9 12.7 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 OAG34686.1 - 2.3e-30 105.7 21.0 2e-29 102.7 18.6 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 OAG34686.1 - 1.5e-06 27.8 1.4 1.5e-06 27.8 1.4 2.3 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB TRI12 PF06609.13 OAG34686.1 - 1.4e-05 23.7 0.5 1.4e-05 23.7 0.5 2.4 3 0 0 3 3 3 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 OAG34686.1 - 0.0023 16.3 4.5 0.39 8.9 0.2 2.4 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family DUF3792 PF12670.7 OAG34686.1 - 1.3 9.2 13.5 0.15 12.2 2.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3792) TauD PF02668.16 OAG34687.1 - 3.2e-35 122.2 0.0 4.3e-35 121.8 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Sirohm_synth_C PF14823.6 OAG34687.1 - 0.047 13.3 1.2 0.23 11.1 0.3 2.2 2 0 0 2 2 2 0 Sirohaem biosynthesis protein C-terminal SNF2_N PF00176.23 OAG34688.1 - 3.1e-53 180.7 0.4 7e-53 179.6 0.4 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain VIGSSK PF14773.6 OAG34688.1 - 4.7e-22 77.9 0.3 4.7e-22 77.9 0.3 2.1 2 0 0 2 2 2 1 Helicase-associated putative binding domain, C-terminal Helicase_C PF00271.31 OAG34688.1 - 5.8e-21 74.9 0.0 2.3e-18 66.6 0.0 2.7 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 OAG34688.1 - 1.5e-06 27.6 0.1 4.1e-06 26.2 0.1 1.7 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 OAG34688.1 - 1.7e-06 28.2 0.1 8.9e-06 25.8 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 OAG34688.1 - 0.00035 20.4 0.0 0.00076 19.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF2961 PF11175.8 OAG34688.1 - 0.031 13.9 0.1 0.057 13.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2961) NYN PF01936.18 OAG34690.1 - 8.9e-30 104.1 0.0 1.2e-29 103.7 0.0 1.1 1 0 0 1 1 1 1 NYN domain PIN7 PF18475.1 OAG34690.1 - 0.064 13.9 0.0 0.16 12.6 0.0 1.7 1 1 0 1 1 1 0 PIN domain zf-RING_5 PF14634.6 OAG34691.1 - 0.012 15.6 11.8 0.02 14.9 11.8 1.3 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.6 OAG34691.1 - 0.02 15.2 9.2 0.035 14.5 9.2 1.4 1 0 0 1 1 1 0 Ring finger domain zf-RING_6 PF14835.6 OAG34691.1 - 0.11 12.4 1.6 0.22 11.4 1.6 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C3HC4 PF00097.25 OAG34691.1 - 0.4 10.6 11.3 0.69 9.8 11.3 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OAG34691.1 - 0.48 10.3 5.6 0.92 9.4 5.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAG34691.1 - 0.82 9.7 10.3 1.5 8.9 10.3 1.5 1 0 0 1 1 1 0 RING-type zinc-finger AMP-binding PF00501.28 OAG34692.1 - 1.1e-67 228.5 0.0 1.3e-67 228.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG34692.1 - 4.9e-18 65.9 0.7 1.1e-17 64.7 0.7 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Gpr1_Fun34_YaaH PF01184.19 OAG34693.1 - 1.4e-37 129.3 18.8 1.7e-37 129.0 18.8 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Fungal_trans PF04082.18 OAG34694.1 - 1.2e-21 77.0 0.7 2e-21 76.2 0.7 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sugar_tr PF00083.24 OAG34695.1 - 5.6e-78 262.8 22.7 6.8e-78 262.5 22.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG34695.1 - 5e-25 88.2 33.7 3.3e-16 59.2 14.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily AA_permease_C PF13906.6 OAG34695.1 - 0.062 13.4 3.0 0.087 12.9 0.9 2.4 2 0 0 2 2 2 0 C-terminus of AA_permease Fungal_trans_2 PF11951.8 OAG34696.1 - 3.2e-08 32.8 0.5 4.9e-08 32.2 0.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG34696.1 - 3.2e-08 33.5 11.0 4.8e-08 33.0 11.0 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2256 PF10013.9 OAG34697.1 - 1.4e-08 34.7 1.0 4.1e-08 33.2 1.0 1.8 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2256) TetR_C_11 PF16859.5 OAG34697.1 - 0.092 13.1 0.8 0.2 12.0 0.8 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain zf-RING_7 PF02591.15 OAG34697.1 - 0.18 12.0 0.9 6.1 7.1 0.2 2.9 3 0 0 3 3 3 0 C4-type zinc ribbon domain Ecl1 PF12855.7 OAG34697.1 - 0.43 11.7 2.7 0.54 11.4 0.2 2.1 2 1 0 2 2 2 0 ECL1/2/3 zinc binding proteins Aldo_ket_red PF00248.21 OAG34698.1 - 2.8e-61 207.3 0.0 3.2e-61 207.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Rcd1 PF04078.13 OAG34699.1 - 4.8e-119 396.4 0.0 8.8e-119 395.5 0.0 1.4 1 1 0 1 1 1 1 Cell differentiation family, Rcd1-like SbcCD_C PF13558.6 OAG34699.1 - 0.068 13.4 1.2 0.16 12.2 1.2 1.6 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit PAT1 PF09770.9 OAG34699.1 - 5.1 5.2 15.4 5.9 5.0 15.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Glycophorin_A PF01102.18 OAG34700.1 - 0.092 13.0 3.7 0.23 11.7 3.7 1.7 1 1 0 1 1 1 0 Glycophorin A DUF202 PF02656.15 OAG34700.1 - 0.4 11.1 3.4 5 7.7 0.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF202) bZIP_1 PF00170.21 OAG34701.1 - 1.7e-08 34.4 14.8 2.4e-08 34.0 13.9 1.7 1 1 0 1 1 1 1 bZIP transcription factor ATG16 PF08614.11 OAG34701.1 - 1.2e-05 25.6 9.1 1.7e-05 25.2 9.1 1.1 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) TolA_bind_tri PF16331.5 OAG34701.1 - 0.00015 21.8 9.3 0.27 11.3 9.0 2.4 2 0 0 2 2 2 2 TolA binding protein trimerisation TPR_MLP1_2 PF07926.12 OAG34701.1 - 0.00041 20.4 6.7 0.0007 19.7 6.7 1.3 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein UPF0242 PF06785.11 OAG34701.1 - 0.0007 19.8 4.7 0.00088 19.4 4.7 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus DUF812 PF05667.11 OAG34701.1 - 0.00086 18.3 3.8 0.0011 18.0 3.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) DUF3450 PF11932.8 OAG34701.1 - 0.001 18.5 7.1 0.002 17.5 7.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) Jnk-SapK_ap_N PF09744.9 OAG34701.1 - 0.002 18.3 7.2 0.0034 17.6 7.2 1.3 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 FPP PF05911.11 OAG34701.1 - 0.0036 15.6 2.9 0.0043 15.3 2.9 1.0 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil SHE3 PF17078.5 OAG34701.1 - 0.0043 16.8 2.2 0.0073 16.0 2.2 1.3 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 Fib_alpha PF08702.10 OAG34701.1 - 0.0057 16.8 6.7 0.032 14.4 7.5 1.7 2 0 0 2 2 2 1 Fibrinogen alpha/beta chain family bZIP_2 PF07716.15 OAG34701.1 - 0.0073 16.4 20.3 0.22 11.7 14.5 2.3 1 1 1 2 2 2 2 Basic region leucine zipper Macoilin PF09726.9 OAG34701.1 - 0.0095 14.5 4.7 0.01 14.4 4.7 1.0 1 0 0 1 1 1 1 Macoilin family DUF3323 PF11796.8 OAG34701.1 - 0.01 15.7 0.3 0.014 15.3 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function N-terminus (DUF3323) COG7 PF10191.9 OAG34701.1 - 0.012 13.9 4.7 0.018 13.3 4.7 1.2 1 0 0 1 1 1 0 Golgi complex component 7 (COG7) DUF16 PF01519.16 OAG34701.1 - 0.013 16.0 2.8 0.021 15.3 2.8 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF16 DUF4618 PF15397.6 OAG34701.1 - 0.016 14.6 5.5 0.024 14.0 5.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) ADIP PF11559.8 OAG34701.1 - 0.027 14.5 7.9 0.049 13.7 7.9 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding HIP1_clath_bdg PF16515.5 OAG34701.1 - 0.03 14.9 12.4 0.12 13.0 12.5 1.9 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 TMF_DNA_bd PF12329.8 OAG34701.1 - 0.05 13.6 6.3 0.052 13.6 5.0 1.6 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding KxDL PF10241.9 OAG34701.1 - 0.056 13.7 7.8 0.084 13.2 7.2 1.5 2 0 0 2 2 1 0 Uncharacterized conserved protein DUF724 PF05266.14 OAG34701.1 - 0.067 13.0 6.7 0.1 12.4 6.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF1664 PF07889.12 OAG34701.1 - 0.071 13.1 1.1 0.13 12.3 1.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) HemX PF04375.14 OAG34701.1 - 0.072 12.4 7.8 0.099 11.9 7.8 1.2 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase TSC22 PF01166.18 OAG34701.1 - 0.074 13.4 2.7 1.5 9.2 0.2 2.5 1 1 1 2 2 2 0 TSC-22/dip/bun family U1snRNP70_N PF12220.8 OAG34701.1 - 0.083 13.5 4.4 0.19 12.4 4.4 1.6 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Exonuc_VII_L PF02601.15 OAG34701.1 - 0.094 12.3 6.4 0.12 11.9 6.4 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Seryl_tRNA_N PF02403.22 OAG34701.1 - 0.098 12.9 3.5 0.16 12.2 3.5 1.3 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain FapA PF03961.13 OAG34701.1 - 0.11 11.0 2.9 0.15 10.6 2.9 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF4407 PF14362.6 OAG34701.1 - 0.15 11.4 7.1 0.24 10.7 6.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) bZIP_Maf PF03131.17 OAG34701.1 - 0.22 12.1 16.2 0.37 11.4 16.2 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor DUF3682 PF12446.8 OAG34701.1 - 0.23 12.0 4.0 0.3 11.6 4.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) FUSC PF04632.12 OAG34701.1 - 0.23 9.9 0.7 0.26 9.8 0.7 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF1151 PF06625.11 OAG34701.1 - 0.25 11.3 11.1 0.38 10.7 11.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1151) SlyX PF04102.12 OAG34701.1 - 0.28 11.8 9.6 0.17 12.5 7.2 1.9 1 1 1 2 2 1 0 SlyX TMPIT PF07851.13 OAG34701.1 - 0.32 10.2 4.4 0.43 9.8 4.4 1.1 1 0 0 1 1 1 0 TMPIT-like protein DivIC PF04977.15 OAG34701.1 - 0.71 9.7 13.0 0.071 12.9 2.9 2.2 1 1 1 2 2 2 0 Septum formation initiator SOBP PF15279.6 OAG34701.1 - 0.72 10.4 8.3 0.92 10.1 8.3 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein ABC_tran_CTD PF16326.5 OAG34701.1 - 2.8 8.3 11.7 0.81 10.0 0.9 2.3 1 1 0 2 2 2 0 ABC transporter C-terminal domain DUF4200 PF13863.6 OAG34701.1 - 3 8.2 14.5 11 6.4 14.5 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) ZapB PF06005.12 OAG34701.1 - 4.2 7.9 13.8 0.61 10.6 6.9 2.2 1 1 1 2 2 2 0 Cell division protein ZapB Csm1_N PF18504.1 OAG34701.1 - 5.5 7.4 11.5 0.23 11.8 2.0 2.4 1 1 0 2 2 2 0 Csm1 N-terminal domain SnoaL_3 PF13474.6 OAG34702.1 - 4.1e-06 27.0 0.0 8.3e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 OAG34702.1 - 0.0099 16.3 0.0 0.025 15.0 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4440) EthD PF07110.11 OAG34703.1 - 9.4e-19 68.4 0.1 2e-18 67.3 0.1 1.5 1 1 0 1 1 1 1 EthD domain MmlI PF09448.10 OAG34703.1 - 2e-06 28.2 0.0 2.7e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Methylmuconolactone methyl-isomerase Zn_clus PF00172.18 OAG34704.1 - 3.5e-07 30.2 8.7 6.3e-07 29.4 8.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAG34704.1 - 0.00032 19.8 0.2 0.00085 18.4 0.2 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Herpes_DNAp_acc PF04929.12 OAG34704.1 - 0.11 11.4 5.6 0.16 10.9 0.6 2.3 2 0 0 2 2 2 0 Herpes DNA replication accessory factor Mito_carr PF00153.27 OAG34705.1 - 4.5e-07 29.7 0.4 0.00012 21.9 0.1 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein CoA_trans PF01144.23 OAG34706.1 - 1.4e-100 335.1 2.2 6.4e-61 205.5 0.2 2.1 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.6 OAG34706.1 - 0.0029 17.6 0.1 0.007 16.3 0.1 1.6 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain Megourin PF17560.2 OAG34706.1 - 0.078 13.2 0.0 0.94 9.8 0.0 2.4 2 0 0 2 2 2 0 Aphid Megourins AcetylCoA_hydro PF02550.15 OAG34706.1 - 0.11 12.5 0.0 4.5 7.2 0.0 2.8 3 0 0 3 3 3 0 Acetyl-CoA hydrolase/transferase N-terminal domain NCOA_u2 PF16665.5 OAG34707.1 - 0.0027 18.0 0.1 0.15 12.3 0.1 2.3 1 1 0 1 1 1 1 Unstructured region on nuclear receptor coactivator protein MFS_1 PF07690.16 OAG34708.1 - 1.1e-36 126.6 29.5 1.6e-36 126.0 29.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Ceramidase PF05875.12 OAG34708.1 - 0.086 12.2 1.0 0.16 11.4 0.2 1.8 1 1 0 1 1 1 0 Ceramidase Cupin_2 PF07883.11 OAG34709.1 - 2e-07 30.6 0.0 3.5e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 OAG34709.1 - 0.13 12.0 0.0 0.31 10.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF861) DUF3405 PF11885.8 OAG34710.1 - 2.4e-229 762.3 1.9 3e-229 761.9 1.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) Glyco_hydro_17 PF00332.18 OAG34711.1 - 3.9e-22 79.2 0.5 2.8e-21 76.4 0.9 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 17 Cu-oxidase_3 PF07732.15 OAG34712.1 - 2e-43 147.2 1.8 8.9e-43 145.1 0.7 2.6 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.22 OAG34712.1 - 3.3e-41 141.0 1.7 2.4e-40 138.3 0.1 2.5 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 OAG34712.1 - 2.3e-38 131.0 4.7 2.1e-35 121.4 0.1 3.9 3 1 0 3 3 3 2 Multicopper oxidase Phosphoesterase PF04185.14 OAG34713.1 - 9.6e-36 123.7 1.5 3.1e-35 122.0 1.5 1.7 1 1 0 1 1 1 1 Phosphoesterase family HIF-1a_CTAD PF08778.10 OAG34713.1 - 0.15 11.7 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 HIF-1 alpha C terminal transactivation domain DUF3328 PF11807.8 OAG34714.1 - 1.2e-13 51.4 0.2 1.8e-13 50.8 0.2 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) UL45 PF05473.12 OAG34714.1 - 0.23 11.1 0.0 0.38 10.3 0.0 1.3 1 0 0 1 1 1 0 UL45 protein, carbohydrate-binding C-type lectin-like DUF3328 PF11807.8 OAG34715.1 - 5.2e-29 101.6 0.2 1e-20 74.5 0.0 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF3328) AAA_24 PF13479.6 OAG34716.1 - 0.00063 19.5 1.4 6.3 6.5 0.1 3.2 2 1 0 3 3 3 3 AAA domain DUF4096 PF13340.6 OAG34716.1 - 0.02 15.1 4.3 25 5.2 0.1 3.5 3 0 0 3 3 3 0 Putative transposase of IS4/5 family (DUF4096) PEX-2N PF09263.10 OAG34716.1 - 0.055 13.8 0.8 95 3.4 0.0 3.3 3 0 0 3 3 3 0 Peroxisome biogenesis factor 1, N-terminal EFTUD2 PF16004.5 OAG34716.1 - 1.3 9.6 15.7 8.9 6.9 0.4 3.7 1 1 2 3 3 3 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus DUF3343 PF11823.8 OAG34716.1 - 3.3 7.2 4.5 40 3.8 0.1 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3343) SET PF00856.28 OAG34717.1 - 2.8e-11 44.1 0.0 7.8e-11 42.7 0.0 1.8 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.18 OAG34717.1 - 1.6e-07 31.2 9.9 1.6e-07 31.2 9.9 3.8 4 0 0 4 4 4 1 MYND finger AAA PF00004.29 OAG34718.1 - 3.7e-17 63.0 0.0 6.5e-17 62.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OAG34718.1 - 0.015 15.7 0.1 3.2 8.1 0.0 2.8 1 1 0 2 2 2 0 AAA ATPase domain Fungal_trans PF04082.18 OAG34719.1 - 1.3e-10 40.8 0.0 1.9e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF1275 PF06912.11 OAG34720.1 - 1e-42 146.2 19.9 1.3e-42 145.9 19.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) SNF2_N PF00176.23 OAG34721.1 - 5.1e-60 203.0 0.0 7.4e-60 202.5 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OAG34721.1 - 2.4e-12 47.2 0.0 4.5e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG34721.1 - 1.5e-06 28.3 0.0 3.2e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 OAG34721.1 - 0.002 17.4 0.0 0.0034 16.6 0.0 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase zf-C3HC4_3 PF13920.6 OAG34721.1 - 0.0048 16.7 5.2 0.009 15.9 5.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OAG34721.1 - 0.0075 16.1 5.3 0.015 15.1 5.3 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 OAG34721.1 - 0.016 15.2 6.5 0.031 14.2 6.5 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_6 PF14835.6 OAG34721.1 - 1.2 9.1 4.0 3 7.8 4.0 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C2H2 PF00096.26 OAG34722.1 - 6.4e-07 29.5 21.1 0.0067 16.8 0.0 5.0 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAG34722.1 - 7.1e-05 23.3 17.8 0.075 13.9 0.1 4.7 4 0 0 4 4 4 2 C2H2-type zinc finger NACHT PF05729.12 OAG34722.1 - 0.00022 21.2 0.9 0.43 10.5 0.1 2.9 1 1 1 2 2 2 2 NACHT domain zf-C2H2_3rep PF18868.1 OAG34722.1 - 0.001 19.7 5.0 0.0041 17.8 5.0 2.1 1 0 0 1 1 1 1 Zinc finger C2H2-type, 3 repeats Goodbye PF17109.5 OAG34722.1 - 0.0054 17.2 0.0 0.027 14.9 0.0 2.3 3 0 0 3 3 2 1 fungal STAND N-terminal Goodbye domain NB-ARC PF00931.22 OAG34722.1 - 0.012 14.8 0.0 0.031 13.5 0.0 1.7 1 0 0 1 1 1 0 NB-ARC domain DUF2075 PF09848.9 OAG34722.1 - 0.029 13.6 0.0 0.065 12.5 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA PF00004.29 OAG34722.1 - 0.033 14.6 0.1 0.12 12.8 0.1 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) KAP_NTPase PF07693.14 OAG34722.1 - 0.058 12.6 0.0 0.13 11.5 0.0 1.6 1 0 0 1 1 1 0 KAP family P-loop domain Torsin PF06309.11 OAG34722.1 - 0.073 13.2 0.0 0.35 11.0 0.0 2.1 2 0 0 2 2 2 0 Torsin zinc_ribbon_9 PF14369.6 OAG34722.1 - 0.083 13.2 0.3 1.1 9.6 0.0 2.7 2 0 0 2 2 2 0 zinc-ribbon AAA_25 PF13481.6 OAG34722.1 - 0.084 12.4 0.0 0.39 10.2 0.0 2.1 1 1 0 1 1 1 0 AAA domain zf-C2H2_6 PF13912.6 OAG34722.1 - 0.1 12.7 0.1 0.1 12.7 0.1 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 OAG34722.1 - 0.1 12.7 1.0 0.39 10.9 1.0 2.1 1 0 0 1 1 1 0 Zinc ribbon domain Zn_ribbon_recom PF13408.6 OAG34722.1 - 0.24 12.0 5.7 0.82 10.2 5.7 1.9 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain zf-met PF12874.7 OAG34722.1 - 0.31 11.5 2.7 55 4.3 0.0 3.9 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 OAG34722.1 - 2.7 8.6 22.4 0.6 10.6 0.2 5.1 5 1 0 5 5 4 0 Zinc-finger double domain zf-C2H2_jaz PF12171.8 OAG34722.1 - 7.3 7.0 6.9 60 4.1 0.1 3.9 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding HET PF06985.11 OAG34723.1 - 6.9e-24 84.9 0.0 1.4e-23 83.9 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.16 OAG34724.1 - 3.3e-30 105.2 31.5 3.3e-30 105.2 31.5 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Aminotran_1_2 PF00155.21 OAG34725.1 - 4.3e-40 138.0 0.0 5.3e-40 137.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 OAG34725.1 - 4.7e-06 25.4 0.0 7.6e-06 24.7 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 OAG34725.1 - 7.8e-06 25.1 0.0 1.6e-05 24.0 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class-V Alliinase_C PF04864.13 OAG34725.1 - 0.0084 15.0 0.2 0.018 14.0 0.2 1.5 1 1 0 1 1 1 1 Allinase Beta_elim_lyase PF01212.21 OAG34725.1 - 0.065 12.5 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase DUF4452 PF14618.6 OAG34725.1 - 0.17 11.7 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4452) TPR_MLP1_2 PF07926.12 OAG34727.1 - 0.034 14.2 3.1 0.034 14.2 3.1 2.5 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein AIG1 PF04548.16 OAG34727.1 - 0.037 13.3 0.0 0.037 13.3 0.0 2.1 2 1 0 3 3 3 0 AIG1 family Pneumo_NS1 PF03438.13 OAG34727.1 - 0.13 12.4 0.0 0.23 11.6 0.0 1.3 1 0 0 1 1 1 0 Pneumovirus NS1 protein Membralin PF09746.9 OAG34727.1 - 0.34 9.9 5.6 0.46 9.5 5.6 1.1 1 0 0 1 1 1 0 Tumour-associated protein ADIP PF11559.8 OAG34727.1 - 1.1 9.3 29.1 4.9 7.2 12.2 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding MMR_HSR1 PF01926.23 OAG34727.1 - 1.2 9.2 3.3 1.8 8.7 0.0 2.6 2 1 0 2 2 2 0 50S ribosome-binding GTPase FlaC_arch PF05377.11 OAG34727.1 - 2.1 8.8 16.6 3.5 8.1 3.0 3.5 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF1515 PF07439.11 OAG34727.1 - 2.8 8.0 7.4 5.6 7.0 5.6 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1515) DUF4407 PF14362.6 OAG34727.1 - 2.8 7.2 14.2 4.4 6.6 14.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HAUS-augmin3 PF14932.6 OAG34727.1 - 3 7.4 22.4 8.4 5.9 22.2 1.7 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 LMBR1 PF04791.16 OAG34727.1 - 5.9 5.7 8.0 6.9 5.4 8.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Exonuc_VII_L PF02601.15 OAG34727.1 - 9.7 5.6 12.6 14 5.1 12.6 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit MMR_HSR1 PF01926.23 OAG34728.1 - 5.4e-08 32.9 0.0 1.8e-07 31.2 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase AIG1 PF04548.16 OAG34728.1 - 5.3e-05 22.7 1.0 7.1e-05 22.2 0.0 1.8 2 0 0 2 2 2 1 AIG1 family ABC_tran PF00005.27 OAG34728.1 - 7.2e-05 23.3 0.1 0.00037 21.0 0.1 2.4 1 1 0 1 1 1 1 ABC transporter SRPRB PF09439.10 OAG34728.1 - 0.00032 20.2 0.0 0.00067 19.1 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 OAG34728.1 - 0.00035 20.5 0.0 0.00099 19.0 0.0 1.7 1 0 0 1 1 1 1 RsgA GTPase GBP PF02263.19 OAG34728.1 - 0.0016 17.8 0.1 0.005 16.1 0.1 1.8 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain AAA_22 PF13401.6 OAG34728.1 - 0.013 15.7 0.7 0.072 13.4 0.0 2.4 2 1 0 2 2 2 0 AAA domain KAP_NTPase PF07693.14 OAG34728.1 - 0.038 13.2 0.5 0.14 11.4 0.4 2.0 1 1 0 1 1 1 0 KAP family P-loop domain AAA_18 PF13238.6 OAG34728.1 - 0.1 13.2 0.7 0.51 10.9 0.0 2.5 3 0 0 3 3 3 0 AAA domain Dynamin_N PF00350.23 OAG34728.1 - 0.19 11.8 12.3 0.6 10.2 0.2 4.0 2 2 1 4 4 4 0 Dynamin family DUF87 PF01935.17 OAG34728.1 - 0.22 11.6 0.1 0.22 11.6 0.1 2.8 2 1 0 2 2 2 0 Helicase HerA, central domain AAA_33 PF13671.6 OAG34728.1 - 0.62 10.2 3.5 0.67 10.1 0.0 2.6 2 1 0 2 2 2 0 AAA domain Pox_A11 PF05061.13 OAG34728.1 - 1.1 8.5 3.4 1.9 7.7 3.3 1.5 1 1 0 1 1 1 0 Poxvirus A11 Protein Carboxyl_trans PF01039.22 OAG34729.1 - 9.6e-76 255.4 0.0 1.7e-75 254.6 0.0 1.4 1 1 0 1 1 1 1 Carboxyl transferase domain DUF5427 PF10310.9 OAG34729.1 - 0.093 11.7 0.1 0.12 11.3 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Sugar_tr PF00083.24 OAG34730.1 - 9.8e-81 271.9 22.3 1e-80 271.8 21.5 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG34730.1 - 1.9e-32 112.6 29.2 3.7e-32 111.6 29.1 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Folate_carrier PF01770.18 OAG34730.1 - 1.6e-05 23.8 0.2 2.5e-05 23.2 0.2 1.2 1 0 0 1 1 1 1 Reduced folate carrier TRI12 PF06609.13 OAG34730.1 - 0.00058 18.4 4.4 0.00058 18.4 4.4 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) FAD_binding_3 PF01494.19 OAG34731.1 - 1.5e-46 159.2 0.0 5e-46 157.5 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain APH PF01636.23 OAG34731.1 - 1.7e-17 64.1 0.0 4.3e-17 62.9 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family NAD_binding_8 PF13450.6 OAG34731.1 - 0.0078 16.4 0.0 0.016 15.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAG34731.1 - 0.0083 15.7 0.0 1.6 8.3 0.0 2.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG34731.1 - 0.029 13.6 0.0 0.049 12.9 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 OAG34731.1 - 0.046 13.4 0.0 0.094 12.4 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Thi4 PF01946.17 OAG34731.1 - 0.073 12.3 0.1 0.19 11.0 0.0 1.6 2 0 0 2 2 2 0 Thi4 family Fructosamin_kin PF03881.14 OAG34731.1 - 0.11 11.6 0.0 0.48 9.6 0.0 1.9 2 0 0 2 2 2 0 Fructosamine kinase SE PF08491.10 OAG34731.1 - 0.11 11.5 0.0 2.1 7.3 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase Pyr_redox_3 PF13738.6 OAG34731.1 - 0.15 11.3 0.3 0.35 10.1 0.2 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAG34731.1 - 0.16 10.7 0.0 0.28 9.9 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.27 OAG34731.1 - 0.17 12.4 0.0 0.92 10.1 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HET PF06985.11 OAG34732.1 - 3.8e-26 92.2 0.1 7.9e-26 91.1 0.1 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) zinc_ribbon_9 PF14369.6 OAG34732.1 - 0.015 15.5 0.8 0.048 13.9 0.8 1.9 1 0 0 1 1 1 0 zinc-ribbon FMN_dh PF01070.18 OAG34733.1 - 1.2e-112 376.4 0.0 1.5e-112 376.1 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 OAG34733.1 - 5.6e-18 64.9 0.0 2e-17 63.1 0.0 2.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 OAG34733.1 - 0.00012 21.4 0.0 0.0002 20.6 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.15 OAG34733.1 - 0.0002 20.9 0.2 0.00032 20.2 0.2 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase ThiG PF05690.14 OAG34733.1 - 0.00027 20.3 0.0 0.011 15.1 0.0 2.5 2 0 0 2 2 2 1 Thiazole biosynthesis protein ThiG IMPDH PF00478.25 OAG34733.1 - 0.0024 16.9 0.2 0.0067 15.5 0.1 1.8 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain Fungal_trans PF04082.18 OAG34734.1 - 1.4e-14 53.8 0.0 2.4e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sox17_18_mid PF12067.8 OAG34734.1 - 0.067 13.2 1.9 0.14 12.2 0.4 2.2 2 0 0 2 2 2 0 Sox 17/18 central domain TMEM171 PF15471.6 OAG34736.1 - 0.14 11.1 4.6 0.21 10.5 4.6 1.3 1 0 0 1 1 1 0 Transmembrane protein family 171 RAP1 PF07218.11 OAG34736.1 - 1.6 6.9 4.0 2.7 6.2 4.0 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) FAM199X PF15814.5 OAG34736.1 - 6.1 5.8 9.2 5.2 6.0 5.6 2.0 2 0 0 2 2 2 0 Protein family FAM199X CoA_trans PF01144.23 OAG34737.1 - 4.3e-101 336.8 1.3 4.4e-61 206.0 0.7 2.0 2 0 0 2 2 2 2 Coenzyme A transferase FRQ PF09421.10 OAG34738.1 - 2.8e-95 320.3 41.9 6.4e-91 305.9 34.1 3.3 2 1 1 3 3 3 3 Frequency clock protein ATG22 PF11700.8 OAG34739.1 - 5.1e-127 424.4 24.5 6e-127 424.2 24.5 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 OAG34739.1 - 4.4e-14 52.2 28.3 6.3e-08 31.9 1.9 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily CTF_NFI PF00859.18 OAG34740.1 - 0.0078 16.2 1.2 0.0096 15.9 1.2 1.1 1 0 0 1 1 1 1 CTF/NF-I family transcription modulation region AF-4 PF05110.13 OAG34740.1 - 0.022 12.9 11.4 0.025 12.7 11.4 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein INO80_Ies4 PF08193.11 OAG34740.1 - 0.094 12.7 4.2 0.12 12.3 4.2 1.1 1 0 0 1 1 1 0 INO80 complex subunit Ies4 SR-25 PF10500.9 OAG34740.1 - 0.13 11.8 9.4 0.18 11.4 9.4 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein IMUP PF15761.5 OAG34740.1 - 0.55 10.9 7.3 0.91 10.2 7.3 1.3 1 0 0 1 1 1 0 Immortalisation up-regulated protein Acetyltransf_1 PF00583.25 OAG34741.1 - 2e-05 24.8 0.0 4.9e-05 23.5 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OAG34741.1 - 5.7e-05 23.5 0.0 0.00031 21.1 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OAG34741.1 - 0.00033 20.6 0.0 0.00063 19.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAG34741.1 - 0.01 15.8 0.0 0.018 15.0 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein AMP-binding PF00501.28 OAG34742.1 - 5e-74 249.4 0.0 6.2e-74 249.1 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG34742.1 - 4.8e-17 62.7 0.1 1e-16 61.7 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain bZIP_1 PF00170.21 OAG34743.1 - 3.7e-05 23.7 6.7 6.6e-05 22.9 6.7 1.5 1 0 0 1 1 1 1 bZIP transcription factor hemP PF10636.9 OAG34743.1 - 0.023 14.5 0.1 0.59 10.0 0.0 2.3 2 0 0 2 2 2 0 Hemin uptake protein hemP DUF2383 PF09537.10 OAG34743.1 - 0.077 13.3 0.4 0.11 12.8 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2383) bZIP_2 PF07716.15 OAG34743.1 - 0.082 13.0 6.2 0.73 10.0 6.2 2.3 1 1 0 1 1 1 0 Basic region leucine zipper ATG16 PF08614.11 OAG34743.1 - 0.091 13.0 7.9 0.13 12.5 7.9 1.3 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF3446 PF11928.8 OAG34744.1 - 4.8 7.6 12.5 0.22 11.9 4.6 2.4 2 0 0 2 2 2 0 Early growth response N-terminal domain Ribo_biogen_C PF04034.13 OAG34745.1 - 7.2e-52 174.4 0.0 1.1e-51 173.9 0.0 1.3 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 OAG34745.1 - 8e-10 38.4 0.3 1.8e-09 37.2 0.3 1.6 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI PPV_E1_N PF00524.18 OAG34745.1 - 3.6 8.0 8.3 0.32 11.4 2.4 2.2 1 1 1 2 2 2 0 E1 Protein, N terminal domain Nop14 PF04147.12 OAG34745.1 - 4.5 5.4 18.2 6.2 4.9 18.2 1.1 1 0 0 1 1 1 0 Nop14-like family ECR1_N PF14382.6 OAG34746.1 - 4e-13 48.9 0.0 1.1e-12 47.5 0.0 1.8 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region KH_6 PF15985.5 OAG34746.1 - 2.3e-05 24.7 0.3 4.5e-05 23.7 0.3 1.5 1 0 0 1 1 1 1 KH domain EXOSC1 PF10447.9 OAG34746.1 - 0.0031 18.1 2.3 0.76 10.4 0.1 3.0 3 1 0 3 3 3 2 Exosome component EXOSC1/CSL4 NTP_transf_9 PF04248.12 OAG34749.1 - 1.1e-36 124.5 0.0 8e-30 102.6 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF427) Med1 PF10744.9 OAG34750.1 - 2.7e-72 244.1 0.0 3.4e-72 243.8 0.0 1.1 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 Catalase PF00199.19 OAG34751.1 - 5e-174 578.9 0.1 6.3e-174 578.5 0.1 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 OAG34751.1 - 6.5e-15 55.1 0.0 2e-14 53.6 0.0 1.8 1 0 0 1 1 1 1 Catalase-related immune-responsive DUF1360 PF07098.11 OAG34752.1 - 0.1 12.5 0.1 1 9.3 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1360) FAA_hydrolase PF01557.18 OAG34753.1 - 3.6e-58 196.8 0.0 4e-58 196.7 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Glyoxalase PF00903.25 OAG34754.1 - 1.5e-10 41.3 1.9 8.4e-07 29.2 1.2 2.6 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 OAG34754.1 - 6.8e-05 23.1 0.1 0.0077 16.5 0.1 2.4 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Peptidase_S10 PF00450.22 OAG34755.1 - 1e-85 288.7 0.1 1.3e-85 288.4 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase G_glu_transpept PF01019.21 OAG34756.1 - 2.7e-141 471.8 0.0 3.2e-141 471.6 0.0 1.1 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Elong_Iki1 PF10483.9 OAG34757.1 - 1.7e-82 277.3 0.0 9.8e-82 274.8 0.0 1.8 1 1 0 1 1 1 1 Elongator subunit Iki1 PNGaseA PF12222.8 OAG34758.1 - 7.9e-156 519.3 0.2 1e-155 518.9 0.2 1.1 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A Cyclin_N PF00134.23 OAG34759.1 - 0.027 14.2 0.0 0.12 12.2 0.0 2.0 2 0 0 2 2 2 0 Cyclin, N-terminal domain TFIIB PF00382.19 OAG34759.1 - 0.065 13.3 0.0 8.6 6.5 0.1 2.3 2 0 0 2 2 2 0 Transcription factor TFIIB repeat T-box_assoc PF16176.5 OAG34761.1 - 0.093 12.8 2.5 0.11 12.5 0.6 1.8 1 1 1 2 2 2 0 T-box transcription factor-associated Methyltransf_25 PF13649.6 OAG34762.1 - 2.5e-14 53.7 0.0 5.3e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG34762.1 - 7.8e-13 48.5 0.0 1.2e-12 47.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAG34762.1 - 1.3e-12 47.9 0.0 3.6e-12 46.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAG34762.1 - 4.2e-11 42.6 0.0 1.2e-10 41.1 0.0 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 OAG34762.1 - 6.2e-11 42.8 0.0 2.2e-10 41.0 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG34762.1 - 1.1e-09 38.9 0.0 2.5e-09 37.8 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 OAG34762.1 - 0.00012 21.9 0.0 0.00043 20.1 0.0 1.8 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.19 OAG34762.1 - 0.00037 20.7 0.0 0.00054 20.1 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.14 OAG34762.1 - 0.0026 17.3 0.0 0.0054 16.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain p450 PF00067.22 OAG34763.1 - 2.3e-44 151.9 0.0 3e-44 151.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Filo_VP35 PF02097.15 OAG34764.1 - 0.045 12.8 0.0 0.055 12.5 0.0 1.0 1 0 0 1 1 1 0 Filoviridae VP35 DUF1180 PF06679.12 OAG34765.1 - 1.2 9.5 8.0 0.053 13.9 2.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) SNRNP27 PF08648.12 OAG34766.1 - 2e-25 88.6 1.5 3.8e-25 87.7 1.5 1.5 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins Autophagy_N PF03986.13 OAG34767.1 - 4.7e-44 149.7 0.1 1.1e-43 148.4 0.0 1.7 2 0 0 2 2 2 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_C PF10381.9 OAG34767.1 - 5.9e-16 57.7 0.6 1e-15 56.9 0.6 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal Autophagy_act_C PF03987.15 OAG34767.1 - 3e-14 53.3 0.5 5.2e-14 52.6 0.5 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Catalase PF00199.19 OAG34768.1 - 3.7e-161 536.5 0.0 4.6e-161 536.2 0.0 1.1 1 0 0 1 1 1 1 Catalase Catalase_C PF18011.1 OAG34768.1 - 2.3e-43 147.4 0.1 3.8e-43 146.7 0.1 1.4 1 0 0 1 1 1 1 C-terminal domain found in long catalases Catalase-rel PF06628.12 OAG34768.1 - 6.3e-17 61.6 0.7 1.1e-16 60.8 0.0 1.8 2 0 0 2 2 2 1 Catalase-related immune-responsive AvrB_AvrC PF05394.11 OAG34768.1 - 0.2 10.9 0.0 0.3 10.2 0.0 1.2 1 0 0 1 1 1 0 Avirulence protein Promethin PF16015.5 OAG34769.1 - 2.5e-23 82.0 15.6 3.3e-23 81.6 15.6 1.2 1 0 0 1 1 1 1 Promethin Zn_clus PF00172.18 OAG34770.1 - 0.00034 20.7 12.2 0.00034 20.7 12.2 2.0 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 OAG34771.1 - 3.9e-38 131.3 48.1 3.7e-37 128.1 41.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG34771.1 - 7.2e-10 38.3 10.7 7.2e-10 38.3 10.7 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter UL42 PF17638.2 OAG34771.1 - 0.18 11.8 1.1 1.2 9.1 0.1 2.6 2 0 0 2 2 2 0 HCMV UL42 MFS_1_like PF12832.7 OAG34771.1 - 9.8 4.9 18.2 0.16 10.8 10.3 2.1 2 0 0 2 2 2 0 MFS_1 like family 4HBT PF03061.22 OAG34773.1 - 6.6e-08 32.8 0.2 1e-07 32.2 0.2 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 OAG34773.1 - 0.0045 17.3 0.2 0.0095 16.2 0.1 1.6 1 1 1 2 2 2 1 Thioesterase-like superfamily Alpha-amylase PF00128.24 OAG34774.1 - 6.6e-28 98.2 0.7 1.5e-27 97.0 0.7 1.5 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.18 OAG34774.1 - 2.4e-05 24.7 0.0 0.00051 20.5 0.0 2.4 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain DUF1939 PF09154.10 OAG34774.1 - 7.5e-05 22.8 0.0 0.00015 21.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1939) Glyco_hydro_70 PF02324.16 OAG34774.1 - 0.00031 19.1 0.2 0.21 9.7 0.0 3.0 3 0 0 3 3 3 3 Glycosyl hydrolase family 70 p450 PF00067.22 OAG34775.1 - 1.3e-57 195.6 0.0 2.3e-57 194.8 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 ADH_N PF08240.12 OAG34776.1 - 2e-30 104.9 0.6 3.4e-30 104.1 0.6 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG34776.1 - 2.4e-22 79.3 2.5 2.4e-22 79.3 2.5 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase DASH_Hsk3 PF08227.11 OAG34776.1 - 9e-21 74.0 3.5 2e-20 72.9 3.4 1.7 2 0 0 2 2 2 1 DASH complex subunit Hsk3 like ADH_zinc_N_2 PF13602.6 OAG34776.1 - 8e-08 33.4 0.2 3.5e-07 31.3 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase TrkA_N PF02254.18 OAG34776.1 - 0.0039 17.4 1.2 0.01 16.1 0.7 2.0 2 0 0 2 2 2 1 TrkA-N domain MTS PF05175.14 OAG34776.1 - 0.021 14.4 0.2 0.047 13.2 0.2 1.6 1 0 0 1 1 1 0 Methyltransferase small domain Shikimate_DH PF01488.20 OAG34776.1 - 0.11 12.5 0.3 0.27 11.3 0.3 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Shisa PF13908.6 OAG34776.1 - 0.21 11.8 0.1 0.33 11.2 0.1 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator 4HBT PF03061.22 OAG34777.1 - 0.051 13.9 0.1 0.59 10.5 0.0 2.5 2 0 0 2 2 2 0 Thioesterase superfamily PKI PF02827.16 OAG34778.1 - 0.013 15.7 0.0 0.035 14.3 0.0 1.7 1 0 0 1 1 1 0 cAMP-dependent protein kinase inhibitor Hexokinase_2 PF03727.16 OAG34779.1 - 3.1e-76 256.0 0.0 4.2e-76 255.5 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 OAG34779.1 - 4.3e-55 186.7 0.2 5.5e-43 147.2 0.1 2.3 1 1 1 2 2 2 2 Hexokinase zf-C2HC5 PF06221.13 OAG34780.1 - 2e-21 75.7 6.7 3.1e-21 75.1 6.7 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type FA_desaturase PF00487.24 OAG34781.1 - 0.029 14.2 0.3 0.045 13.6 0.3 1.2 1 0 0 1 1 1 0 Fatty acid desaturase CPSF_A PF03178.15 OAG34781.1 - 0.11 11.8 0.0 0.3 10.3 0.0 1.6 2 0 0 2 2 2 0 CPSF A subunit region RL10P_insert PF17777.1 OAG34782.1 - 4.8e-22 77.7 0.1 1.8e-21 75.9 0.0 2.0 2 0 0 2 2 2 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 OAG34782.1 - 4.9e-18 65.1 0.1 1.1e-17 64.0 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_60s PF00428.19 OAG34782.1 - 3.9e-17 62.6 8.2 6.2e-17 62.0 6.3 2.1 2 0 0 2 2 2 1 60s Acidic ribosomal protein BSP PF04450.12 OAG34783.1 - 2.2e-66 223.6 0.0 2.6e-66 223.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase of plants and bacteria CLASP_N PF12348.8 OAG34784.1 - 3.6e-43 147.8 0.0 6.7e-43 146.9 0.0 1.4 1 0 0 1 1 1 1 CLASP N terminal Excalibur PF05901.11 OAG34784.1 - 0.039 14.6 0.0 0.093 13.4 0.0 1.7 1 0 0 1 1 1 0 Excalibur calcium-binding domain Arm PF00514.23 OAG34784.1 - 0.051 13.6 0.0 0.14 12.2 0.0 1.8 1 0 0 1 1 1 0 Armadillo/beta-catenin-like repeat RhoGAP PF00620.27 OAG34785.1 - 2.5e-47 160.5 0.6 5.4e-47 159.4 0.0 1.9 2 0 0 2 2 2 1 RhoGAP domain LIM PF00412.22 OAG34785.1 - 8.5e-14 51.5 18.0 2.8e-09 37.1 1.8 2.4 2 0 0 2 2 2 2 LIM domain Zn-ribbon_8 PF09723.10 OAG34785.1 - 0.83 9.8 16.5 1.8 8.8 1.2 3.9 3 1 0 3 3 3 0 Zinc ribbon domain CENP-H PF05837.12 OAG34785.1 - 3 8.3 11.5 0.085 13.3 1.0 3.1 2 1 0 2 2 2 0 Centromere protein H (CENP-H) TF_Zn_Ribbon PF08271.12 OAG34785.1 - 6.2 6.4 14.4 1.2 8.7 0.8 4.4 4 1 1 5 5 5 0 TFIIB zinc-binding zf-ribbon_3 PF13248.6 OAG34785.1 - 8.2 6.0 20.8 2.2 7.8 3.7 4.6 5 1 0 5 5 5 0 zinc-ribbon domain Sec3_C PF09763.9 OAG34787.1 - 2.4e-192 641.0 14.8 3e-192 640.7 14.8 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.6 OAG34787.1 - 1.3e-25 89.4 0.1 3.9e-25 87.8 0.0 1.9 2 0 0 2 2 2 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Vps52 PF04129.12 OAG34787.1 - 0.0022 16.8 1.9 0.2 10.4 0.1 2.2 2 0 0 2 2 2 2 Vps52 / Sac2 family zf-C2H2 PF00096.26 OAG34788.1 - 1.4e-13 50.4 27.3 4.6e-05 23.7 0.5 5.0 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OAG34788.1 - 1.4e-09 37.9 16.3 0.00064 20.0 0.7 4.6 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 OAG34788.1 - 0.00015 22.3 24.4 0.027 15.3 0.4 4.9 5 0 0 5 5 5 4 C2H2-type zinc finger zf-met PF12874.7 OAG34788.1 - 0.0021 18.4 2.9 0.95 10.0 0.0 3.5 3 0 0 3 3 3 2 Zinc-finger of C2H2 type FOXP-CC PF16159.5 OAG34788.1 - 0.0037 17.8 1.5 1.9 9.2 0.1 2.5 2 0 0 2 2 2 2 FOXP coiled-coil domain zf-C2H2_jaz PF12171.8 OAG34788.1 - 0.0043 17.3 2.4 5.8 7.3 0.0 3.8 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 OAG34788.1 - 7.9 6.6 7.1 15 5.7 0.1 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger Hpt PF01627.23 OAG34790.1 - 6.6e-12 45.5 0.1 1e-11 44.9 0.1 1.3 1 0 0 1 1 1 1 Hpt domain Aminotran_1_2 PF00155.21 OAG34791.1 - 7.1e-91 305.1 0.0 8.5e-91 304.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II SART-1 PF03343.13 OAG34792.1 - 1.2e-158 529.5 74.8 1.4e-158 529.3 74.8 1.0 1 0 0 1 1 1 1 SART-1 family Suc_Fer-like PF06999.12 OAG34793.1 - 2e-66 223.6 0.0 2.6e-66 223.2 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Spore_coat_CotO PF14153.6 OAG34793.1 - 0.048 13.6 2.9 0.072 13.0 2.9 1.2 1 0 0 1 1 1 0 Spore coat protein CotO Protamine_P2 PF00841.19 OAG34793.1 - 0.092 13.2 0.8 0.23 12.0 0.1 2.0 2 0 0 2 2 2 0 Sperm histone P2 DOCK_N PF16172.5 OAG34794.1 - 1.2e-85 287.8 2.1 4.3e-85 285.9 0.0 2.2 2 0 0 2 2 2 1 DOCK N-terminus DOCK-C2 PF14429.6 OAG34794.1 - 2.7e-31 108.9 0.1 1e-30 107.1 0.0 2.0 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins SH3_9 PF14604.6 OAG34794.1 - 7.8e-06 25.7 0.0 2.4e-05 24.1 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 OAG34794.1 - 1.2e-05 24.8 0.0 2.7e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 SH3 domain Sde2_N_Ubi PF13019.6 OAG34795.1 - 2.7e-58 196.4 0.1 4.1e-58 195.9 0.1 1.3 1 0 0 1 1 1 1 Silencing defective 2 N-terminal ubiquitin domain PBP1_TM PF14812.6 OAG34795.1 - 0.029 14.7 0.3 0.029 14.7 0.3 2.9 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal p450 PF00067.22 OAG34796.1 - 1.6e-41 142.5 0.0 3.9e-41 141.3 0.0 1.6 2 0 0 2 2 2 1 Cytochrome P450 Clr5 PF14420.6 OAG34797.1 - 5.6e-17 61.7 0.8 1.1e-16 60.8 0.8 1.5 1 0 0 1 1 1 1 Clr5 domain DnaJ_C PF01556.18 OAG34798.1 - 7.5e-39 133.2 0.1 9.8e-39 132.8 0.1 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 OAG34798.1 - 2.4e-25 88.4 2.7 3.9e-25 87.7 2.7 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 OAG34798.1 - 1.9e-15 57.0 19.0 3.1e-15 56.3 19.0 1.4 1 0 0 1 1 1 1 DnaJ central domain LPD39 PF18858.1 OAG34798.1 - 0.13 12.3 0.6 0.22 11.6 0.6 1.3 1 0 0 1 1 1 0 Large polyvalent protein associated domain 39 zf_Rg PF17915.1 OAG34798.1 - 0.39 10.1 7.1 0.13 11.7 0.6 2.7 2 0 0 2 2 2 0 Reverse gyrase zinc finger HypA PF01155.19 OAG34798.1 - 1.6 8.8 10.8 1.9 8.5 2.2 2.4 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc-ribbons_6 PF07191.12 OAG34798.1 - 4.6 7.3 9.6 6.5 6.8 1.7 2.3 1 1 0 2 2 2 0 zinc-ribbons DUF2614 PF11023.8 OAG34798.1 - 8.2 6.6 7.1 6 7.0 0.7 2.2 1 1 1 2 2 2 0 Zinc-ribbon containing domain Sulfate_transp PF00916.20 OAG34799.1 - 2.7e-110 368.7 18.7 4.3e-110 368.0 18.7 1.3 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 OAG34799.1 - 9.1e-10 38.2 0.0 1.8e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 OAG34799.1 - 0.018 15.4 3.2 0.018 15.4 3.2 3.2 2 2 1 3 3 3 0 Molybdate transporter of MFS superfamily SNN_transmemb PF09049.10 OAG34799.1 - 0.019 14.9 0.7 0.019 14.9 0.7 2.7 3 0 0 3 3 3 0 Stannin transmembrane MFS_1 PF07690.16 OAG34800.1 - 4.4e-31 108.1 44.6 4.1e-30 104.9 34.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG34800.1 - 1.2e-11 44.2 10.9 1.2e-11 44.2 10.9 1.8 2 1 0 2 2 2 1 Sugar (and other) transporter Xan_ur_permease PF00860.20 OAG34801.1 - 5.1e-62 209.8 30.7 7.6e-61 205.9 30.7 2.0 1 1 0 1 1 1 1 Permease family Sugar_tr PF00083.24 OAG34802.1 - 1.7e-86 290.9 12.0 1.9e-86 290.7 12.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG34802.1 - 1.2e-28 100.1 16.4 1.7e-28 99.6 16.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 OAG34802.1 - 1.4e-07 30.5 9.3 0.00016 20.4 0.6 2.6 2 0 0 2 2 2 2 MFS/sugar transport protein TRI12 PF06609.13 OAG34802.1 - 6.1e-05 21.6 0.6 6.1e-05 21.6 0.6 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) PTR2 PF00854.21 OAG34802.1 - 0.28 10.0 9.9 0.42 9.4 1.7 2.5 2 1 0 2 2 2 0 POT family DUF1682 PF07946.14 OAG34804.1 - 2.1e-106 355.8 0.6 2.5e-106 355.6 0.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) Peptidase_M20 PF01546.28 OAG34806.1 - 1.8e-24 86.6 0.0 1e-19 71.1 0.0 2.4 2 0 0 2 2 2 2 Peptidase family M20/M25/M40 WD40 PF00400.32 OAG34806.1 - 4.6e-10 39.9 9.1 0.031 15.1 0.0 6.7 6 1 0 6 6 6 3 WD domain, G-beta repeat M20_dimer PF07687.14 OAG34806.1 - 1e-05 25.4 0.0 2.6e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain ANAPC4_WD40 PF12894.7 OAG34806.1 - 1.1e-05 25.6 0.1 0.15 12.3 0.0 3.8 2 2 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 OAG34806.1 - 0.00074 19.9 0.5 0.06 13.9 0.0 3.5 4 0 0 4 4 4 1 PQQ-like domain WD40_like PF17005.5 OAG34806.1 - 0.0028 17.0 0.0 0.22 10.8 0.0 2.4 2 0 0 2 2 2 1 WD40-like domain Asparaginase_2 PF01112.18 OAG34807.1 - 3.1e-55 187.4 0.0 8.9e-51 172.7 0.0 2.8 3 0 0 3 3 3 2 Asparaginase Transket_pyr PF02779.24 OAG34808.1 - 2.1e-42 144.8 0.0 3.4e-42 144.1 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 OAG34808.1 - 6.7e-32 110.0 0.0 1.6e-31 108.8 0.0 1.6 2 0 0 2 2 2 1 Transketolase, C-terminal domain DUF21 PF01595.20 OAG34809.1 - 1.8e-33 115.7 0.0 3.1e-33 115.0 0.0 1.3 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 OAG34809.1 - 3.7e-06 27.3 1.0 0.014 15.8 0.0 3.2 2 1 0 2 2 2 2 CBS domain PikAIV_N PF18605.1 OAG34810.1 - 0.0038 16.8 10.5 0.0038 16.8 10.5 3.9 4 0 0 4 4 4 1 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain AI-2E_transport PF01594.16 OAG34810.1 - 0.21 10.7 2.4 0.13 11.4 0.1 1.8 2 0 0 2 2 2 0 AI-2E family transporter PSI_PsaF PF02507.15 OAG34810.1 - 1.4 8.7 7.2 0.15 11.9 1.3 2.5 2 0 0 2 2 2 0 Photosystem I reaction centre subunit III PKcGMP_CC PF16808.5 OAG34810.1 - 3.6 7.5 21.2 0.069 13.0 0.8 6.0 6 0 0 6 6 6 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Glyco_hydro_15 PF00723.21 OAG34811.1 - 6.3e-52 176.8 0.0 7.9e-45 153.5 0.0 2.1 1 1 1 2 2 2 2 Glycosyl hydrolases family 15 TPT PF03151.16 OAG34812.1 - 1.3e-15 57.5 21.7 3.7e-15 56.0 21.7 1.7 1 1 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 OAG34812.1 - 4.4e-05 23.7 42.4 0.0013 18.9 8.2 3.0 3 0 0 3 3 3 2 EamA-like transporter family DUF2681 PF10883.8 OAG34812.1 - 0.0072 16.7 0.0 0.02 15.3 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2681) Plasmodium_Vir PF05795.11 OAG34812.1 - 0.085 12.3 0.0 0.55 9.6 0.0 2.0 2 0 0 2 2 2 0 Plasmodium vivax Vir protein PUNUT PF16913.5 OAG34812.1 - 0.15 11.2 21.4 0.77 8.9 21.4 1.9 1 1 0 1 1 1 0 Purine nucleobase transmembrane transport DUF3949 PF13133.6 OAG34812.1 - 1.2 9.7 6.0 11 6.6 0.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3949) DUF3430 PF11912.8 OAG34813.1 - 0.00022 21.4 0.9 0.00027 21.1 0.2 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3430) Rick_17kDa_Anti PF05433.15 OAG34813.1 - 0.05 13.5 2.6 0.14 12.1 2.6 1.8 1 0 0 1 1 1 0 Glycine zipper 2TM domain DUF5082 PF16888.5 OAG34813.1 - 0.11 12.8 0.1 0.18 12.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) PilA4 PF18682.1 OAG34813.1 - 0.27 11.6 3.4 9.4 6.7 0.9 2.7 2 0 0 2 2 2 0 Pilin A4 PRCC PF10253.9 OAG34815.1 - 0.055 14.3 4.0 0.073 13.9 4.0 1.1 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting SOG2 PF10428.9 OAG34815.1 - 0.31 10.2 7.8 0.43 9.7 7.8 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein AD PF09793.9 OAG34817.1 - 1.2e-19 70.2 0.0 1.8e-19 69.6 0.0 1.3 1 0 0 1 1 1 1 Anticodon-binding domain Pro_Al_protease PF02983.14 OAG34817.1 - 0.041 13.9 2.6 0.048 13.7 0.3 2.3 2 0 0 2 2 2 0 Alpha-lytic protease prodomain 6PGD PF00393.19 OAG34818.1 - 8e-128 425.8 0.0 1e-127 425.5 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 OAG34818.1 - 3.3e-50 170.3 0.0 5e-50 169.7 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 OAG34818.1 - 0.035 14.3 0.7 0.096 12.9 0.0 2.1 3 0 0 3 3 3 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase RRM_1 PF00076.22 OAG34819.1 - 1.9e-18 66.0 0.0 3.1e-18 65.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MbeD_MobD PF04899.12 OAG34819.1 - 0.088 12.9 0.1 0.18 11.9 0.1 1.4 1 0 0 1 1 1 0 MbeD/MobD like OB_RNB PF08206.11 OAG34819.1 - 0.12 12.1 0.1 0.23 11.2 0.1 1.4 1 0 0 1 1 1 0 Ribonuclease B OB domain DUF1179 PF06678.11 OAG34819.1 - 0.14 12.2 1.3 0.52 10.3 1.3 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1179) Peptidase_C2 PF00648.21 OAG34820.1 - 1e-61 208.6 0.5 3.3e-60 203.6 0.5 2.3 1 1 0 1 1 1 1 Calpain family cysteine protease Porin_1 PF00267.21 OAG34820.1 - 0.045 13.2 0.1 0.076 12.4 0.1 1.3 1 0 0 1 1 1 0 Gram-negative porin DDRGK PF09756.9 OAG34820.1 - 0.32 10.5 24.7 0.94 9.0 24.7 1.8 1 0 0 1 1 1 0 DDRGK domain Ferric_reduct PF01794.19 OAG34821.1 - 3.4e-24 85.4 13.0 3.4e-24 85.4 13.0 2.1 2 1 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 OAG34821.1 - 2.9e-06 27.3 0.0 0.0011 19.1 0.0 2.7 2 1 0 2 2 2 2 FAD-binding domain NAD_binding_6 PF08030.12 OAG34821.1 - 6e-06 26.5 1.2 0.012 15.8 0.0 2.3 1 1 1 2 2 2 2 Ferric reductase NAD binding domain YTH PF04146.15 OAG34822.1 - 3.3e-40 137.8 0.0 5e-40 137.2 0.0 1.3 1 0 0 1 1 1 1 YT521-B-like domain RRM_1 PF00076.22 OAG34822.1 - 0.0055 16.5 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 OAG34822.1 - 0.039 13.7 0.0 0.076 12.8 0.0 1.4 1 0 0 1 1 1 0 Rrp7 RRM-like N-terminal domain Zn_clus PF00172.18 OAG34824.1 - 1.2e-08 35.0 6.4 3.5e-08 33.4 6.4 1.9 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Nodulin_late PF07127.11 OAG34824.1 - 0.031 14.6 5.3 0.098 13.0 0.4 2.6 2 0 0 2 2 2 0 Late nodulin protein PTN_MK_C PF01091.18 OAG34825.1 - 0.045 14.1 0.2 0.12 12.8 0.2 1.7 1 0 0 1 1 1 0 PTN/MK heparin-binding protein family, C-terminal domain DUF2278 PF10042.9 OAG34826.1 - 7.5e-67 225.3 0.0 8.5e-67 225.1 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2278) Lipoxygenase PF00305.19 OAG34827.1 - 6.7e-49 166.9 7.1 1e-47 163.0 4.4 2.0 2 0 0 2 2 2 2 Lipoxygenase adh_short_C2 PF13561.6 OAG34828.1 - 1.4e-55 188.4 0.2 1.8e-55 188.0 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG34828.1 - 2.8e-51 173.8 0.5 4.7e-51 173.0 0.4 1.4 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 OAG34828.1 - 5.4e-13 49.2 0.8 8.7e-13 48.6 0.8 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG34828.1 - 3.8e-07 29.8 0.3 6.1e-07 29.2 0.3 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAG34828.1 - 3.6e-05 23.3 0.1 6.8e-05 22.4 0.1 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Glyco_transf_5 PF08323.11 OAG34828.1 - 0.0013 18.5 0.0 0.029 14.1 0.0 2.5 2 1 1 3 3 3 1 Starch synthase catalytic domain Glyco_transf_4 PF13439.6 OAG34828.1 - 0.0023 18.0 0.0 0.65 10.0 0.0 2.6 3 0 0 3 3 3 1 Glycosyltransferase Family 4 NmrA PF05368.13 OAG34828.1 - 0.0028 17.3 0.6 0.0096 15.5 0.3 1.8 2 0 0 2 2 2 1 NmrA-like family Oxidored_nitro PF00148.19 OAG34828.1 - 0.0029 16.4 0.1 0.0054 15.5 0.1 1.4 1 0 0 1 1 1 1 Nitrogenase component 1 type Oxidoreductase THF_DHG_CYH_C PF02882.19 OAG34828.1 - 0.017 14.5 0.2 0.031 13.6 0.2 1.6 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ACT_7 PF13840.6 OAG34828.1 - 0.06 13.1 0.1 1.5 8.7 0.0 2.6 2 0 0 2 2 2 0 ACT domain Glyco_trans_4_4 PF13579.6 OAG34828.1 - 0.074 13.5 0.2 18 5.7 0.0 3.0 3 1 0 3 3 3 0 Glycosyl transferase 4-like domain SPAN PF02510.14 OAG34828.1 - 0.088 12.0 0.0 0.12 11.5 0.0 1.1 1 0 0 1 1 1 0 Surface presentation of antigens protein Ferric_reduct PF01794.19 OAG34829.1 - 8.6e-20 71.1 11.6 8.6e-20 71.1 11.6 1.9 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 OAG34829.1 - 2.5e-15 56.9 0.0 4.2e-13 49.7 0.0 2.5 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 OAG34829.1 - 1e-07 32.0 0.0 4.8e-05 23.4 0.0 2.8 3 0 0 3 3 3 2 FAD-binding domain NAD_binding_1 PF00175.21 OAG34829.1 - 0.068 13.8 0.0 0.13 12.9 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase NAD-binding domain Sm_multidrug_ex PF06695.11 OAG34829.1 - 0.28 11.8 3.9 0.16 12.6 1.0 2.0 2 0 0 2 2 2 0 Putative small multi-drug export protein GAT PF03127.14 OAG34830.1 - 1.4e-16 60.6 1.1 2.8e-16 59.6 1.1 1.6 1 0 0 1 1 1 1 GAT domain VHS PF00790.19 OAG34830.1 - 0.2 11.5 0.0 1.3 8.9 0.0 2.0 2 0 0 2 2 2 0 VHS domain His_Phos_2 PF00328.22 OAG34831.1 - 6.6e-17 61.9 0.0 2.6e-15 56.7 0.0 2.2 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) NmrA PF05368.13 OAG34833.1 - 2.8e-28 99.0 0.0 3.6e-28 98.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG34833.1 - 4.7e-06 26.6 0.0 7.5e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 OAG34833.1 - 0.0092 16.4 0.0 0.017 15.6 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DUF1590 PF07629.11 OAG34833.1 - 0.23 11.3 4.4 0.14 12.0 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1590) UBA_4 PF14555.6 OAG34834.1 - 2.5e-11 43.2 4.0 3.9e-05 23.4 0.4 3.6 4 0 0 4 4 4 2 UBA-like domain TAP_C PF03943.13 OAG34834.1 - 0.00019 21.0 0.8 0.073 12.7 0.1 2.5 2 0 0 2 2 2 2 TAP C-terminal domain CUE PF02845.16 OAG34834.1 - 0.05 13.3 0.1 2.8 7.7 0.0 2.7 2 0 0 2 2 2 0 CUE domain UBA_4 PF14555.6 OAG34835.1 - 2.7e-06 27.1 8.4 0.063 13.1 0.5 4.1 3 1 0 3 3 3 3 UBA-like domain TAP_C PF03943.13 OAG34835.1 - 0.00026 20.5 1.8 6.7 6.4 0.0 3.6 3 0 0 3 3 3 3 TAP C-terminal domain DUF5585 PF17823.1 OAG34835.1 - 0.14 11.1 9.9 0.21 10.5 9.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5585) Dus PF01207.17 OAG34836.1 - 1.3e-58 198.6 0.0 3.3e-58 197.2 0.0 1.7 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) MJ1316 PF04457.12 OAG34836.1 - 2.3e-22 79.5 1.2 5.9e-22 78.2 1.2 1.8 1 0 0 1 1 1 1 MJ1316 RNA cyclic group end recognition domain Imm39 PF15568.6 OAG34836.1 - 0.066 13.3 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Immunity protein 39 DHO_dh PF01180.21 OAG34836.1 - 0.16 11.2 0.0 0.3 10.3 0.0 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase Abhydrolase_6 PF12697.7 OAG34837.1 - 4.6e-12 47.0 0.2 7.6e-12 46.3 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG34837.1 - 1.4e-06 27.7 0.0 4.1e-06 26.2 0.0 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OAG34837.1 - 1.3e-05 25.0 0.0 0.00014 21.6 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 OAG34837.1 - 0.024 13.5 0.0 0.048 12.6 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase enzyme Ndr PF03096.14 OAG34837.1 - 0.038 12.7 0.0 0.061 12.0 0.0 1.2 1 0 0 1 1 1 0 Ndr family Ser_hydrolase PF06821.13 OAG34837.1 - 0.05 13.4 0.9 0.17 11.7 0.0 2.1 2 0 0 2 2 2 0 Serine hydrolase Clr5 PF14420.6 OAG34838.1 - 2.8e-20 72.3 0.1 1e-19 70.5 0.1 2.0 1 0 0 1 1 1 1 Clr5 domain Mto2_bdg PF12808.7 OAG34838.1 - 0.0044 17.3 0.0 0.0044 17.3 0.0 3.7 5 0 0 5 5 5 1 Micro-tubular organiser Mto1 C-term Mto2-binding region Aldedh PF00171.22 OAG34839.1 - 1.5e-142 475.4 0.0 1.8e-142 475.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 OAG34839.1 - 0.0002 20.5 0.0 0.0011 18.1 0.0 2.2 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) OmdA PF13376.6 OAG34839.1 - 0.051 13.6 1.1 0.14 12.1 1.1 1.8 1 0 0 1 1 1 0 Bacteriocin-protection, YdeI or OmpD-Associated Dehydratase_hem PF13816.6 OAG34841.1 - 2.3e-81 273.6 0.0 2.7e-81 273.4 0.0 1.0 1 0 0 1 1 1 1 Haem-containing dehydratase CN_hydrolase PF00795.22 OAG34842.1 - 5.5e-47 160.3 0.0 7.5e-47 159.9 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Sdh_cyt PF01127.22 OAG34843.1 - 1.5e-12 47.6 7.6 1.6e-12 47.5 7.6 1.0 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF5516 PF17637.2 OAG34843.1 - 2.3 8.0 10.4 1.2 8.9 7.2 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5516) R3H-assoc PF13902.6 OAG34844.1 - 0.16 12.3 3.2 6.2 7.2 0.0 2.7 3 0 0 3 3 3 0 R3H-associated N-terminal domain DIOX_N PF14226.6 OAG34845.1 - 5.4e-35 120.7 0.0 3.3e-33 114.9 0.0 2.3 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OAG34845.1 - 1.4e-14 54.4 0.0 2.5e-14 53.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily GxGYxYP_C PF14323.6 OAG34845.1 - 0.045 13.6 0.0 0.069 13.0 0.0 1.2 1 0 0 1 1 1 0 GxGYxYP putative glycoside hydrolase C-terminal domain FAD-oxidase_C PF02913.19 OAG34846.1 - 4.8e-61 206.6 0.2 7e-61 206.0 0.2 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 OAG34846.1 - 3.8e-38 130.3 0.0 6.8e-38 129.5 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain ADH_N PF08240.12 OAG34847.1 - 4.7e-33 113.3 1.9 7.4e-33 112.7 0.1 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG34847.1 - 3.3e-24 85.3 0.2 5.3e-24 84.7 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 OAG34847.1 - 2.1e-08 33.9 0.4 3.5e-08 33.2 0.4 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 OAG34847.1 - 7.4e-07 28.7 1.1 1.3e-06 27.9 1.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.6 OAG34847.1 - 4.1e-05 24.7 0.0 8.4e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.14 OAG34847.1 - 0.00063 19.4 0.0 0.00098 18.7 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox_2 PF07992.14 OAG34847.1 - 0.0084 15.4 0.5 0.016 14.4 0.5 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_25 PF13649.6 OAG34847.1 - 0.016 15.9 0.0 0.031 15.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 OAG34847.1 - 0.029 13.8 0.3 0.043 13.2 0.3 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 OAG34847.1 - 0.04 13.5 0.1 0.076 12.6 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Met_10 PF02475.16 OAG34847.1 - 0.052 13.3 0.1 0.11 12.2 0.1 1.5 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_11 PF08241.12 OAG34847.1 - 0.061 14.0 0.0 0.14 12.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain DapB_N PF01113.20 OAG34847.1 - 0.11 12.7 0.3 0.23 11.6 0.3 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus SGL PF08450.12 OAG34848.1 - 8.9e-19 68.0 0.4 7.3e-18 65.0 0.4 2.1 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 OAG34848.1 - 0.0014 18.7 0.0 0.0058 16.7 0.0 2.1 2 0 0 2 2 2 1 Strictosidine synthase PD40 PF07676.12 OAG34848.1 - 0.017 15.1 4.0 0.021 14.7 0.1 2.7 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat NHL PF01436.21 OAG34848.1 - 0.045 13.8 0.0 0.35 11.0 0.0 2.5 2 0 0 2 2 2 0 NHL repeat Yae1_N PF09811.9 OAG34849.1 - 2.4e-07 30.3 3.5 4.6e-07 29.4 3.5 1.5 1 0 0 1 1 1 1 Essential protein Yae1, N terminal tRNA-synt_1g PF09334.11 OAG34850.1 - 4.3e-151 503.1 0.0 5.8e-151 502.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 OAG34850.1 - 9.5e-08 30.7 0.2 2.8e-05 22.6 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) DZR PF12773.7 OAG34850.1 - 1.6 8.8 4.6 5.1 7.2 4.3 1.7 1 1 1 2 2 2 0 Double zinc ribbon zf-ribbon_3 PF13248.6 OAG34850.1 - 2.2 7.8 7.8 4.9 6.7 0.6 2.6 2 0 0 2 2 2 0 zinc-ribbon domain Ribosomal_L6e PF01159.19 OAG34850.1 - 3.3 8.3 5.7 8.9 6.9 5.7 1.7 1 0 0 1 1 1 0 Ribosomal protein L6e Glyoxalase PF00903.25 OAG34851.1 - 9.3e-05 22.6 0.0 0.00028 21.1 0.0 1.7 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 OAG34851.1 - 0.0067 16.7 0.0 0.12 12.7 0.0 2.2 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 OAG34851.1 - 0.032 14.1 0.0 9.5 6.2 0.0 2.1 2 0 0 2 2 2 0 Glyoxalase-like domain AIP3 PF03915.13 OAG34853.1 - 0.053 12.6 0.0 0.069 12.2 0.0 1.1 1 0 0 1 1 1 0 Actin interacting protein 3 zf-C4H2 PF10146.9 OAG34853.1 - 0.083 13.2 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 Zinc finger-containing protein GLTT PF01744.20 OAG34853.1 - 0.2 11.5 0.5 0.41 10.4 0.5 1.5 1 0 0 1 1 1 0 GLTT repeat (6 copies) MFS_1 PF07690.16 OAG34854.1 - 3.5e-07 29.5 19.4 3.5e-07 29.5 19.4 2.5 2 1 1 3 3 3 1 Major Facilitator Superfamily DUF3487 PF11990.8 OAG34854.1 - 0.18 11.7 4.5 0.45 10.4 0.4 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3487) Fungal_trans PF04082.18 OAG34855.1 - 2.5e-22 79.2 0.2 5.3e-22 78.1 0.2 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain FAD_binding_3 PF01494.19 OAG34856.1 - 1.5e-19 70.4 0.0 3.7e-19 69.2 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAG34856.1 - 2.8e-09 37.0 5.9 0.00079 19.1 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG34856.1 - 5.8e-08 32.3 0.4 0.00027 20.3 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG34856.1 - 1.1e-06 28.8 1.0 5.1e-05 23.4 0.4 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 OAG34856.1 - 2.7e-06 26.4 0.8 0.00027 19.8 0.7 2.1 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 OAG34856.1 - 1.3e-05 24.5 3.4 2.4e-05 23.6 3.4 1.4 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.24 OAG34856.1 - 2.6e-05 23.7 0.5 0.0017 17.7 0.0 2.4 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 OAG34856.1 - 0.0003 21.3 0.6 0.024 15.2 0.3 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 OAG34856.1 - 0.00054 19.3 0.4 0.0015 17.9 0.1 1.8 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 OAG34856.1 - 0.0008 18.6 1.8 0.03 13.4 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein GIDA PF01134.22 OAG34856.1 - 0.0014 17.8 0.8 0.0072 15.4 1.3 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 OAG34856.1 - 0.0015 18.0 3.4 0.0015 18.0 3.4 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 OAG34856.1 - 0.011 15.1 0.3 0.041 13.1 0.2 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 OAG34856.1 - 0.048 12.5 4.0 0.051 12.4 0.6 2.2 2 1 0 3 3 3 0 Tryptophan halogenase FMO-like PF00743.19 OAG34856.1 - 0.079 11.4 0.4 0.11 10.8 0.4 1.1 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like NAD_binding_9 PF13454.6 OAG34856.1 - 0.31 11.0 3.9 1.2 9.1 0.1 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 OAG34857.1 - 5.9e-93 311.9 0.0 7.3e-93 311.6 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAG34857.1 - 3e-06 27.1 0.1 0.03 13.9 0.0 2.6 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG34857.1 - 0.0013 18.0 0.0 0.0032 16.7 0.0 1.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG34857.1 - 0.011 16.0 0.1 0.039 14.2 0.0 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 OAG34857.1 - 0.074 12.3 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAG34857.1 - 0.088 12.0 0.0 0.18 11.0 0.0 1.6 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.24 OAG34857.1 - 0.11 11.5 0.9 1.1 8.3 0.3 2.5 2 1 0 3 3 3 0 FAD binding domain Glyoxalase PF00903.25 OAG34858.1 - 4.8e-12 46.2 3.1 4.6e-10 39.8 0.7 2.5 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily JCAD PF15351.6 OAG34858.1 - 0.27 9.0 0.0 0.37 8.5 0.0 1.2 1 0 0 1 1 1 0 Junctional protein associated with coronary artery disease p450 PF00067.22 OAG34859.1 - 7.8e-57 193.0 0.0 9.5e-57 192.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.25 OAG34860.1 - 6.8e-36 123.6 0.1 9.2e-36 123.1 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG34860.1 - 1.6e-34 119.5 0.1 2.7e-34 118.8 0.1 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG34860.1 - 4.2e-12 46.3 0.5 4.8e-10 39.6 0.0 2.1 2 0 0 2 2 2 1 KR domain Pyr_redox PF00070.27 OAG34860.1 - 0.0032 18.0 0.3 0.025 15.1 0.1 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GDP_Man_Dehyd PF16363.5 OAG34860.1 - 0.039 13.4 0.1 0.19 11.1 0.0 1.9 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Glyco_tran_WecB PF03808.13 OAG34860.1 - 0.043 13.8 0.1 2.4 8.1 0.0 2.4 2 1 1 3 3 3 0 Glycosyl transferase WecB/TagA/CpsF family ADH_zinc_N PF00107.26 OAG34860.1 - 0.051 13.6 0.1 0.14 12.1 0.0 1.7 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Polysacc_synt_2 PF02719.15 OAG34860.1 - 0.057 12.5 0.0 0.098 11.8 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein AlaDh_PNT_C PF01262.21 OAG34860.1 - 0.063 12.6 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DUF1776 PF08643.10 OAG34860.1 - 0.069 12.5 0.1 0.11 11.9 0.1 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 OAG34860.1 - 0.079 12.4 0.1 0.17 11.3 0.1 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family ECH_1 PF00378.20 OAG34861.1 - 9.5e-39 133.2 0.0 1.2e-38 132.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAG34861.1 - 1.1e-20 74.5 0.0 1.3e-20 74.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Lipase_3 PF01764.25 OAG34861.1 - 0.12 12.2 0.0 0.3 10.9 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) UPF0160 PF03690.13 OAG34862.1 - 9.1e-127 423.1 0.0 1e-126 422.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) ICE2 PF08426.10 OAG34863.1 - 1e-142 476.1 6.1 1.2e-142 475.9 6.1 1.0 1 0 0 1 1 1 1 ICE2 Endosulfine PF04667.17 OAG34864.1 - 1.4e-29 102.0 0.2 2.4e-29 101.3 0.2 1.3 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region RNA_Me_trans PF04252.13 OAG34865.1 - 4.3e-79 264.8 0.0 5e-79 264.5 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase Fungal_trans_2 PF11951.8 OAG34866.1 - 3.4e-08 32.7 0.8 5.7e-08 32.0 0.8 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pribosyltran PF00156.27 OAG34867.1 - 2.2e-06 27.3 0.0 3.8e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Atx10homo_assoc PF09759.9 OAG34868.1 - 0.0068 16.4 0.1 0.036 14.1 0.1 2.2 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain zf-C2H2 PF00096.26 OAG34869.1 - 2e-14 53.1 35.2 3.3e-05 24.1 0.6 5.4 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-met PF12874.7 OAG34869.1 - 5e-05 23.5 16.9 0.0074 16.6 1.0 4.7 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 OAG34869.1 - 0.00075 19.7 2.2 0.029 14.7 0.2 4.3 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 OAG34869.1 - 0.0016 19.1 43.4 0.016 16.0 0.5 6.2 6 0 0 6 6 6 4 C2H2-type zinc finger zf_UBZ PF18439.1 OAG34869.1 - 0.0084 15.7 3.6 5 6.8 0.1 3.7 3 0 0 3 3 3 1 Ubiquitin-Binding Zinc Finger zf-LYAR PF08790.11 OAG34869.1 - 0.063 13.2 6.6 5.9 6.9 0.4 3.8 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger zf-C2H2_6 PF13912.6 OAG34869.1 - 0.12 12.4 0.6 0.12 12.4 0.6 5.1 4 1 1 5 5 5 0 C2H2-type zinc finger zf-C2H2_11 PF16622.5 OAG34869.1 - 0.7 9.7 10.4 3.4 7.5 0.3 3.4 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-H2C2_2 PF13465.6 OAG34869.1 - 0.77 10.3 38.1 0.83 10.2 0.1 5.9 6 0 0 6 6 6 0 Zinc-finger double domain MbeD_MobD PF04899.12 OAG34870.1 - 0.18 12.0 0.0 0.4 10.8 0.0 1.5 1 0 0 1 1 1 0 MbeD/MobD like PKD_channel PF08016.12 OAG34871.1 - 0.0015 17.3 0.5 0.0024 16.6 0.5 1.3 1 0 0 1 1 1 1 Polycystin cation channel DUF1989 PF09347.10 OAG34872.1 - 1.7e-28 99.4 0.0 5.9e-28 97.6 0.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF1989) Rhomboid PF01694.22 OAG34873.1 - 2.1e-33 115.5 11.1 2.1e-33 115.5 11.1 1.9 2 0 0 2 2 2 1 Rhomboid family Homez PF11569.8 OAG34873.1 - 0.0054 16.2 0.3 2.6 7.6 0.0 2.4 2 0 0 2 2 2 2 Homeodomain leucine-zipper encoding, Homez SPT_ssu-like PF11779.8 OAG34874.1 - 6e-15 54.6 2.1 6e-15 54.6 2.1 1.8 1 1 1 2 2 2 1 Small subunit of serine palmitoyltransferase-like AMP-binding PF00501.28 OAG34876.1 - 2.7e-53 181.1 0.0 1.9e-52 178.3 0.0 2.1 2 1 0 2 2 2 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG34876.1 - 6.3e-07 30.3 0.0 1.5e-06 29.1 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain VitD-bind_III PF09164.10 OAG34876.1 - 0.093 12.7 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 Vitamin D binding protein, domain III DASH_Dad3 PF08656.10 OAG34877.1 - 1.4e-26 92.3 0.1 1.7e-26 92.0 0.1 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad3 DUF441 PF04284.13 OAG34877.1 - 0.096 12.7 0.0 0.12 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF441) ApoC-I PF04691.12 OAG34877.1 - 0.21 11.5 0.0 0.32 11.0 0.0 1.3 1 0 0 1 1 1 0 Apolipoprotein C-I (ApoC-1) Ribosomal_S5_C PF03719.15 OAG34878.1 - 1.8e-23 81.8 0.0 3.5e-23 80.9 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 OAG34878.1 - 2.3e-17 62.7 0.0 5.1e-17 61.6 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain LZ_Tnp_IS481 PF13011.6 OAG34878.1 - 0.14 12.7 1.7 1.1 9.8 0.1 2.6 3 0 0 3 3 3 0 leucine-zipper of insertion element IS481 PRMT5_TIM PF17285.2 OAG34879.1 - 2.9e-67 226.6 0.0 4.1e-67 226.1 0.0 1.2 1 0 0 1 1 1 1 PRMT5 TIM barrel domain PRMT5 PF05185.16 OAG34879.1 - 2.5e-65 219.6 0.0 1.1e-47 162.1 0.0 2.2 2 0 0 2 2 2 2 PRMT5 arginine-N-methyltransferase PRMT5_C PF17286.2 OAG34879.1 - 7.9e-37 126.8 0.1 1.3e-35 122.9 0.1 2.4 1 1 0 1 1 1 1 PRMT5 oligomerisation domain Oxidored-like PF09791.9 OAG34880.1 - 3.8e-24 84.1 5.0 7e-24 83.2 5.0 1.5 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal DUF5522 PF17653.1 OAG34880.1 - 0.071 13.1 3.1 0.16 12.0 3.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5522) KI67R PF08065.12 OAG34880.1 - 0.2 12.2 1.6 9 6.9 0.2 2.4 2 0 0 2 2 2 0 KI67R (NUC007) repeat MMR_HSR1 PF01926.23 OAG34881.1 - 4.4e-06 26.7 0.9 0.0001 22.4 0.0 3.3 2 2 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 OAG34881.1 - 0.00029 21.3 0.0 0.0017 18.7 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AIG1 PF04548.16 OAG34881.1 - 0.0014 18.0 0.1 1.9 7.8 0.0 2.9 3 0 0 3 3 3 2 AIG1 family RsgA_GTPase PF03193.16 OAG34881.1 - 0.0038 17.1 0.0 0.02 14.8 0.0 2.2 1 1 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 OAG34881.1 - 0.0066 16.2 0.0 0.017 14.9 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain T2SSE PF00437.20 OAG34881.1 - 0.017 14.2 0.0 0.036 13.1 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein G-alpha PF00503.20 OAG34881.1 - 0.02 14.1 0.5 0.085 12.0 0.1 2.4 2 1 0 2 2 2 0 G-protein alpha subunit GTP_EFTU PF00009.27 OAG34881.1 - 0.022 14.3 0.2 0.078 12.5 0.1 2.0 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain NACHT PF05729.12 OAG34881.1 - 0.035 14.0 0.0 0.11 12.5 0.0 1.8 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 OAG34881.1 - 0.043 14.3 1.9 0.2 12.1 0.0 2.9 3 0 0 3 3 3 0 ABC transporter FtsK_SpoIIIE PF01580.18 OAG34881.1 - 0.053 12.9 0.0 0.33 10.3 0.0 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_22 PF13401.6 OAG34881.1 - 0.064 13.5 0.1 0.38 11.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 OAG34881.1 - 0.069 13.2 2.3 0.39 10.8 0.1 3.2 3 1 0 3 3 3 0 Dynamin family AAA_23 PF13476.6 OAG34881.1 - 0.076 13.5 7.6 0.42 11.1 0.0 3.3 3 0 0 3 3 3 0 AAA domain Septin PF00735.18 OAG34881.1 - 0.08 12.2 0.0 0.08 12.2 0.0 2.7 3 1 0 3 3 3 0 Septin Osmo_CC PF08946.10 OAG34881.1 - 0.1 12.9 0.2 0.33 11.2 0.2 1.9 1 0 0 1 1 1 0 Osmosensory transporter coiled coil DUF87 PF01935.17 OAG34881.1 - 2.2 8.3 0.0 2.2 8.3 0.0 3.6 3 1 0 3 3 3 0 Helicase HerA, central domain FMO-like PF00743.19 OAG34882.1 - 1.2e-14 53.7 3.2 1.7e-11 43.3 2.7 3.7 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OAG34882.1 - 1.8e-09 37.6 0.0 4.2e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 OAG34882.1 - 2.1e-05 23.9 0.1 0.0034 16.6 0.1 3.4 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 OAG34882.1 - 0.00072 19.6 0.1 0.049 13.6 0.0 2.8 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 OAG34882.1 - 0.0026 17.0 0.0 1.8 7.7 0.0 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.23 OAG34882.1 - 0.048 13.7 1.0 13 5.7 0.2 2.9 4 0 0 4 4 4 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Thi4 PF01946.17 OAG34882.1 - 0.22 10.8 0.0 2.2 7.5 0.0 2.1 2 0 0 2 2 2 0 Thi4 family XPC-binding PF09280.11 OAG34882.1 - 0.64 9.8 2.9 4 7.3 0.0 3.0 4 0 0 4 4 4 0 XPC-binding domain Acetyltransf_9 PF13527.7 OAG34883.1 - 7.9e-08 32.4 0.1 1.6e-07 31.5 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OAG34883.1 - 6.4e-07 29.7 0.0 1.3e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OAG34883.1 - 0.00015 21.7 0.0 0.0003 20.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAG34883.1 - 0.00016 21.8 0.0 0.00034 20.8 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_CG PF14542.6 OAG34883.1 - 0.0015 18.6 0.0 0.58 10.3 0.0 2.8 3 0 0 3 3 3 2 GCN5-related N-acetyl-transferase FR47 PF08445.10 OAG34883.1 - 0.009 16.0 0.0 0.021 14.8 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_15 PF17013.5 OAG34883.1 - 0.072 12.5 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 Putative acetyl-transferase IBR PF01485.21 OAG34884.1 - 3.8e-05 23.8 7.1 3.8e-05 23.8 7.1 3.2 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain DEAD PF00270.29 OAG34885.1 - 8.7e-28 97.3 0.0 2.2e-27 96.0 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1998 PF09369.10 OAG34885.1 - 1.1e-20 74.2 0.3 2.7e-20 72.9 0.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) Helicase_C PF00271.31 OAG34885.1 - 3.9e-12 46.5 0.0 1.4e-11 44.7 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CDT1 PF08839.11 OAG34885.1 - 7.7e-07 29.6 0.0 1.3e-06 28.8 0.0 1.4 1 0 0 1 1 1 1 DNA replication factor CDT1 like ResIII PF04851.15 OAG34885.1 - 8.3e-07 29.2 0.0 1.5e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HET PF06985.11 OAG34887.1 - 6.4e-18 65.5 0.1 1.1e-17 64.8 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF3592 PF12158.8 OAG34888.1 - 0.16 12.0 0.3 0.75 9.8 0.0 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3592) DUF997 PF06196.12 OAG34888.1 - 0.24 11.4 0.1 0.24 11.4 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF997) DUF936 PF06075.12 OAG34889.1 - 0.065 12.1 19.1 0.088 11.7 19.1 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) Prefoldin_2 PF01920.20 OAG34890.1 - 1.3e-11 44.3 6.7 5.4e-06 26.3 3.1 2.2 2 0 0 2 2 2 2 Prefoldin subunit Rootletin PF15035.6 OAG34890.1 - 0.0076 16.3 2.6 0.019 15.0 0.0 2.0 2 0 0 2 2 2 1 Ciliary rootlet component, centrosome cohesion Ufd2P_core PF10408.9 OAG34890.1 - 0.048 12.3 0.7 0.058 12.0 0.7 1.1 1 0 0 1 1 1 0 Ubiquitin elongating factor core DUF4407 PF14362.6 OAG34890.1 - 0.097 12.0 2.2 0.13 11.6 2.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Fib_alpha PF08702.10 OAG34890.1 - 0.17 12.0 4.8 2 8.6 0.1 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family SlyX PF04102.12 OAG34890.1 - 0.78 10.4 5.3 7.2 7.3 0.0 2.4 2 0 0 2 2 2 0 SlyX Rho_Binding PF08912.11 OAG34890.1 - 1.3 9.8 8.7 0.68 10.8 0.4 2.3 2 0 0 2 2 2 0 Rho Binding XhlA PF10779.9 OAG34890.1 - 6.9 6.9 6.7 1.2 9.3 0.7 2.2 2 1 0 2 2 2 0 Haemolysin XhlA Ceramidase PF05875.12 OAG34891.1 - 1.5e-101 339.3 14.1 1.8e-101 339.0 14.1 1.0 1 0 0 1 1 1 1 Ceramidase ABC2_membrane_2 PF12679.7 OAG34891.1 - 0.041 13.2 0.2 0.059 12.6 0.2 1.5 1 0 0 1 1 1 0 ABC-2 family transporter protein Collagen PF01391.18 OAG34892.1 - 0.00074 19.2 6.9 0.0016 18.1 6.9 1.5 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) HORMA PF02301.18 OAG34893.1 - 6.2e-13 48.8 0.0 8e-13 48.5 0.0 1.2 1 0 0 1 1 1 1 HORMA domain Glyco_hydro_16 PF00722.21 OAG34894.1 - 0.00027 20.5 0.0 0.00049 19.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 2OG-FeII_Oxy PF03171.20 OAG34896.1 - 4.6e-06 27.1 0.0 1.7e-05 25.3 0.0 1.9 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Amidohydro_1 PF01979.20 OAG34897.1 - 2.1e-59 201.6 0.1 2.6e-59 201.3 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 OAG34897.1 - 2.3e-08 34.0 0.2 5.5e-06 26.1 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family BtrH_N PF14399.6 OAG34897.1 - 0.021 15.1 0.0 0.22 11.8 0.0 2.2 2 0 0 2 2 2 0 Butirosin biosynthesis protein H, N-terminal Hairpins PF04877.12 OAG34897.1 - 0.15 11.7 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 HrpZ AA_permease_2 PF13520.6 OAG34898.1 - 3.6e-63 213.9 53.3 4.4e-63 213.6 53.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAG34898.1 - 2.7e-20 72.4 47.2 3.6e-20 72.0 47.2 1.1 1 0 0 1 1 1 1 Amino acid permease B12D PF06522.11 OAG34898.1 - 0.87 9.4 4.6 2.3 8.1 0.3 3.2 3 0 0 3 3 3 0 NADH-ubiquinone reductase complex 1 MLRQ subunit Methyltransf_24 PF13578.6 OAG34899.1 - 1.4e-11 45.3 0.0 2.4e-11 44.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.17 OAG34899.1 - 2.5e-06 26.8 0.0 3.7e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase GCD14 PF08704.10 OAG34899.1 - 0.028 14.1 0.0 0.045 13.4 0.0 1.3 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit DUF1442 PF07279.11 OAG34899.1 - 0.045 13.1 0.0 0.074 12.4 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1442) ORC6 PF05460.13 OAG34900.1 - 5.9e-33 114.6 0.0 1e-28 100.7 0.4 2.1 1 1 1 2 2 2 2 Origin recognition complex subunit 6 (ORC6) Candida_ALS PF05792.13 OAG34900.1 - 8.5 7.0 11.0 2.2 8.9 6.3 2.5 2 0 0 2 2 2 0 Candida agglutinin-like (ALS) DBR1 PF05011.13 OAG34901.1 - 4e-42 143.9 3.6 4.2e-41 140.6 0.0 3.0 3 0 0 3 3 3 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 OAG34901.1 - 0.0016 19.0 1.8 0.0027 18.2 1.2 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase adh_short PF00106.25 OAG34902.1 - 4.3e-20 72.0 0.0 5.2e-16 58.7 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAG34902.1 - 7e-12 45.4 0.0 1.3e-09 37.9 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG34902.1 - 5.5e-05 23.2 0.0 8.9e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 KR domain bZIP_1 PF00170.21 OAG34903.1 - 4.2e-08 33.2 7.8 3.9e-07 30.1 7.1 2.1 1 1 1 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.15 OAG34903.1 - 0.00061 19.8 5.6 0.022 14.8 3.9 2.1 1 1 1 2 2 2 2 Basic region leucine zipper bZIP_Maf PF03131.17 OAG34903.1 - 0.00082 19.9 4.7 0.0011 19.4 4.7 1.1 1 0 0 1 1 1 1 bZIP Maf transcription factor DivIC PF04977.15 OAG34903.1 - 0.039 13.7 1.6 0.048 13.4 0.1 1.8 1 1 1 2 2 2 0 Septum formation initiator Cluap1 PF10234.9 OAG34903.1 - 0.062 12.7 3.2 0.084 12.3 3.2 1.1 1 0 0 1 1 1 0 Clusterin-associated protein-1 COG5 PF10392.9 OAG34903.1 - 0.11 12.7 0.3 0.14 12.3 0.3 1.2 1 0 0 1 1 1 0 Golgi transport complex subunit 5 DUF4618 PF15397.6 OAG34903.1 - 0.11 11.9 1.2 0.15 11.5 1.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) FAM184 PF15665.5 OAG34904.1 - 0.0012 18.7 44.0 0.0012 18.7 44.0 8.7 2 1 7 9 9 9 3 Family with sequence similarity 184, A and B Filament PF00038.21 OAG34904.1 - 0.58 9.7 222.3 0.014 15.0 18.3 9.0 2 1 6 8 8 8 0 Intermediate filament protein PTPA PF03095.15 OAG34906.1 - 2.8e-113 378.3 0.0 3.3e-113 378.1 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein DUF572 PF04502.13 OAG34907.1 - 1.3e-69 235.4 0.1 1.5e-69 235.2 0.1 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) zf-RING_UBOX PF13445.6 OAG34908.1 - 5.2e-06 26.4 7.0 0.0011 18.9 0.2 2.9 2 1 0 2 2 2 2 RING-type zinc-finger zf-NOSIP PF15906.5 OAG34908.1 - 0.0013 18.8 0.0 0.0022 18.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein zf-RING_5 PF14634.6 OAG34908.1 - 0.0015 18.5 2.1 0.0015 18.5 2.1 3.1 3 0 0 3 3 3 2 zinc-RING finger domain zf-C3HC4 PF00097.25 OAG34908.1 - 0.056 13.3 0.6 0.056 13.3 0.6 3.2 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Carboxyl_trans PF01039.22 OAG34908.1 - 0.36 9.4 3.7 0.54 8.8 3.7 1.2 1 0 0 1 1 1 0 Carboxyl transferase domain zf-RING_2 PF13639.6 OAG34908.1 - 0.62 10.5 12.6 0.17 12.3 1.6 3.0 2 2 0 2 2 2 0 Ring finger domain Sedlin_N PF04628.13 OAG34909.1 - 8.3e-40 135.9 0.0 1e-39 135.6 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 OAG34909.1 - 5.1e-07 29.7 0.0 0.00011 22.2 0.0 2.1 1 1 1 2 2 2 2 Sybindin-like family DUF2040 PF09745.9 OAG34910.1 - 5.7e-37 126.5 19.2 5.7e-37 126.5 19.2 4.1 3 2 0 3 3 3 1 Coiled-coil domain-containing protein 55 (DUF2040) adh_short PF00106.25 OAG34911.1 - 3.2e-45 154.0 0.2 4.1e-45 153.7 0.2 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG34911.1 - 7.2e-39 133.7 0.3 8.2e-39 133.5 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG34911.1 - 8e-13 48.7 0.4 1.1e-12 48.2 0.4 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG34911.1 - 0.00028 20.4 0.1 0.00066 19.2 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF998 PF06197.13 OAG34911.1 - 0.026 14.1 5.3 0.57 9.7 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF998) Ins_P5_2-kin PF06090.12 OAG34912.1 - 1.5e-42 146.2 0.0 5.5e-42 144.4 0.0 1.7 1 1 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase CBM_21 PF03370.13 OAG34916.1 - 4e-37 126.8 1.8 7.7e-37 125.9 1.8 1.5 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 OAG34916.1 - 2.1e-11 44.3 2.6 4.5e-11 43.2 2.6 1.5 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) MCM PF00493.23 OAG34917.1 - 1.1e-100 335.3 0.0 1.6e-100 334.8 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 OAG34917.1 - 7.8e-41 138.9 0.6 1.9e-40 137.6 0.6 1.6 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 OAG34917.1 - 3.1e-29 101.2 0.9 7.8e-29 99.9 0.9 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 OAG34917.1 - 6.3e-18 65.3 0.0 2e-17 63.7 0.0 1.9 1 0 0 1 1 1 1 MCM N-terminal domain AAA_5 PF07728.14 OAG34917.1 - 2e-06 27.9 0.0 6.1e-06 26.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 OAG34917.1 - 3.4e-06 26.6 0.0 0.00013 21.4 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 OAG34917.1 - 0.00097 19.0 0.0 0.0028 17.5 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) WD40 PF00400.32 OAG34918.1 - 1.6e-46 155.3 18.8 3.6e-06 27.6 0.0 8.5 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.7 OAG34918.1 - 1.5e-13 50.4 0.4 2.8e-13 49.5 0.4 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAG34918.1 - 3e-12 46.1 0.3 6.4e-12 45.0 0.3 1.6 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.8 OAG34918.1 - 8e-12 44.6 8.5 0.0044 15.7 0.2 5.8 3 1 3 6 6 6 5 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 OAG34918.1 - 9.1e-08 32.3 0.2 0.3 11.4 0.0 5.2 3 2 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain F-box_4 PF15966.5 OAG34918.1 - 5.3e-06 26.3 0.0 1.5e-05 24.8 0.0 1.8 1 0 0 1 1 1 1 F-box APG17 PF04108.12 OAG34919.1 - 1.3e-113 380.1 6.4 1.6e-113 379.9 6.4 1.0 1 0 0 1 1 1 1 Autophagy protein Apg17 NPV_P10 PF05531.12 OAG34919.1 - 0.015 15.8 2.3 5.8 7.5 0.0 3.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Vps54_N PF10475.9 OAG34919.1 - 0.05 12.9 1.2 1.5 8.0 0.1 2.7 2 0 0 2 2 2 0 Vacuolar-sorting protein 54, of GARP complex DUF1664 PF07889.12 OAG34919.1 - 0.054 13.5 13.0 0.65 10.0 0.3 4.5 4 0 0 4 4 4 0 Protein of unknown function (DUF1664) CDT1_C PF16679.5 OAG34919.1 - 0.075 13.5 0.9 0.67 10.4 0.8 2.6 1 1 0 1 1 1 0 DNA replication factor Cdt1 C-terminal domain P22_AR_C PF10548.9 OAG34919.1 - 0.14 12.3 0.1 3.9 7.7 0.0 3.1 3 0 0 3 3 3 0 P22AR C-terminal domain FH2 PF02181.23 OAG34919.1 - 0.31 10.1 5.6 0.19 10.8 0.1 2.9 2 2 0 3 3 3 0 Formin Homology 2 Domain DUF4795 PF16043.5 OAG34919.1 - 0.37 10.4 13.4 0.024 14.3 1.9 2.7 2 1 0 3 3 3 0 Domain of unknown function (DUF4795) OmpH PF03938.14 OAG34919.1 - 0.59 10.5 14.6 22 5.4 0.1 4.4 4 1 0 4 4 4 0 Outer membrane protein (OmpH-like) FAP206 PF12018.8 OAG34919.1 - 0.88 9.0 10.6 3.5 7.0 0.2 4.1 5 0 0 5 5 5 0 Domain of unknown function Snapin_Pallidin PF14712.6 OAG34919.1 - 1.8 9.1 16.6 0.21 12.1 0.5 4.1 4 0 0 4 4 4 0 Snapin/Pallidin Fzo_mitofusin PF04799.13 OAG34919.1 - 2.1 7.9 12.5 6.2 6.4 0.3 4.2 4 1 0 4 4 4 0 fzo-like conserved region Nsp1_C PF05064.13 OAG34919.1 - 4.2 7.2 9.9 5.5 6.8 0.2 4.0 4 1 0 4 4 4 0 Nsp1-like C-terminal region GCIP PF13324.6 OAG34919.1 - 8.6 5.9 9.3 6.5 6.3 5.2 2.7 2 1 0 2 2 2 0 Grap2 and cyclin-D-interacting RIO1 PF01163.22 OAG34920.1 - 2.5e-69 232.6 0.3 2.5e-69 232.6 0.3 2.4 3 0 0 3 3 3 1 RIO1 family Pkinase_fungal PF17667.1 OAG34920.1 - 0.18 10.5 0.1 0.18 10.5 0.1 2.3 2 0 0 2 2 2 0 Fungal protein kinase SR-25 PF10500.9 OAG34920.1 - 0.43 10.2 27.7 0.041 13.5 22.8 1.7 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein CCDC106 PF15794.5 OAG34920.1 - 2.6 7.7 13.6 9.8 5.8 13.6 2.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 adh_short PF00106.25 OAG34921.1 - 2.4e-34 118.5 0.0 3e-34 118.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG34921.1 - 1.2e-27 96.9 0.0 1.9e-27 96.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG34921.1 - 4.9e-08 33.1 0.0 7.6e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 OAG34921.1 - 0.007 16.3 0.0 0.89 9.4 0.0 2.3 1 1 0 2 2 2 2 NAD(P)H-binding FAD_binding_3 PF01494.19 OAG34922.1 - 3.8e-49 167.8 0.0 5.7e-49 167.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAG34922.1 - 1.3e-08 34.9 0.1 4e-06 26.7 0.1 2.3 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG34922.1 - 4.1e-08 32.8 0.0 6.4e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAG34922.1 - 1.9e-06 28.3 0.0 0.001 19.6 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG34922.1 - 2e-06 27.3 0.0 7.7e-05 22.1 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAG34922.1 - 6.2e-06 25.2 0.3 0.00097 17.9 0.0 2.7 3 0 0 3 3 3 1 HI0933-like protein NAD_binding_8 PF13450.6 OAG34922.1 - 3.3e-05 24.0 0.0 7.9e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 OAG34922.1 - 0.00012 21.5 0.0 0.00024 20.6 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 OAG34922.1 - 0.00045 19.5 0.0 0.00075 18.8 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Amino_oxidase PF01593.24 OAG34922.1 - 0.00062 19.2 0.2 1.4 8.1 0.0 2.7 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.21 OAG34922.1 - 0.0015 17.8 0.1 0.0039 16.5 0.1 1.7 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 OAG34922.1 - 0.0027 17.1 0.0 0.0059 16.0 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 OAG34922.1 - 0.0032 16.6 0.0 0.0057 15.8 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 OAG34922.1 - 0.0079 15.3 0.0 0.014 14.5 0.0 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A ThiF PF00899.21 OAG34922.1 - 0.0095 15.3 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 1 ThiF family TrkA_N PF02254.18 OAG34922.1 - 0.01 16.1 0.0 0.021 15.1 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_7 PF13241.6 OAG34922.1 - 0.012 16.0 0.1 0.077 13.5 0.1 2.3 2 1 0 2 2 2 0 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.14 OAG34922.1 - 0.012 15.2 0.0 0.024 14.2 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.18 OAG34922.1 - 0.025 14.4 0.0 0.047 13.6 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 OAG34922.1 - 0.042 12.9 0.2 0.086 11.9 0.2 1.6 1 1 0 1 1 1 0 Lycopene cyclase protein K_oxygenase PF13434.6 OAG34922.1 - 0.053 12.7 0.0 5.1 6.1 0.0 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) ApbA PF02558.16 OAG34922.1 - 0.082 12.5 0.1 0.19 11.4 0.0 1.6 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.20 OAG34922.1 - 0.11 12.6 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox_2 PF07992.14 OAG34923.1 - 9.1e-44 149.8 0.0 1.3e-43 149.4 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAG34923.1 - 3.1e-15 56.5 0.3 8.8e-13 48.6 0.2 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG34923.1 - 1.1e-07 31.4 0.0 4.6e-07 29.4 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAG34923.1 - 1.6e-07 31.3 0.1 0.4 10.2 0.1 3.5 2 1 1 3 3 3 3 FAD dependent oxidoreductase K_oxygenase PF13434.6 OAG34923.1 - 2.7e-07 30.1 0.0 8.1e-07 28.5 0.0 1.7 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.14 OAG34923.1 - 3.4e-07 29.5 0.5 0.079 11.8 0.1 3.2 2 1 1 3 3 3 3 Tryptophan halogenase Lycopene_cycl PF05834.12 OAG34923.1 - 2.4e-06 26.9 6.2 0.0046 16.1 0.0 3.6 3 1 1 4 4 3 2 Lycopene cyclase protein NAD_binding_9 PF13454.6 OAG34923.1 - 2.9e-06 27.4 0.5 0.98 9.4 0.0 3.9 3 1 1 4 4 4 2 FAD-NAD(P)-binding HI0933_like PF03486.14 OAG34923.1 - 3.1e-06 26.2 0.2 0.13 10.9 0.1 3.8 4 1 1 5 5 5 2 HI0933-like protein NAD_binding_8 PF13450.6 OAG34923.1 - 3.8e-06 27.0 0.0 0.0042 17.3 0.0 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain DUF1188 PF06690.11 OAG34923.1 - 0.00056 19.5 0.1 0.2 11.2 0.0 2.4 2 1 0 2 2 2 2 Protein of unknown function (DUF1188) TrkA_N PF02254.18 OAG34923.1 - 0.0053 17.0 1.0 0.9 9.8 0.1 2.9 3 0 0 3 3 3 1 TrkA-N domain Thi4 PF01946.17 OAG34923.1 - 0.0075 15.5 0.0 0.22 10.7 0.0 2.4 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 OAG34923.1 - 0.012 14.9 1.7 0.18 11.0 0.0 2.9 2 1 1 3 3 3 0 FAD binding domain GIDA PF01134.22 OAG34923.1 - 0.069 12.2 0.9 1.5 7.8 0.9 2.9 3 1 1 4 4 4 0 Glucose inhibited division protein A Eno-Rase_NADH_b PF12242.8 OAG34923.1 - 0.79 9.5 0.0 0.79 9.5 0.0 2.8 3 0 0 3 3 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase FAD_oxidored PF12831.7 OAG34923.1 - 5.4 6.2 9.6 4.5 6.5 0.1 3.3 4 0 0 4 4 3 0 FAD dependent oxidoreductase Caps_synth PF05704.12 OAG34924.1 - 8.6e-11 41.7 0.0 1.9e-10 40.6 0.0 1.5 1 1 0 1 1 1 1 Capsular polysaccharide synthesis protein Gly_transf_sug PF04488.15 OAG34924.1 - 3.2e-07 30.9 0.0 7.3e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif SMC_N PF02463.19 OAG34925.1 - 6.2e-55 186.0 32.6 2.3e-54 184.2 32.6 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 OAG34925.1 - 7.5e-27 94.0 0.2 7.6e-26 90.7 0.0 2.8 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 OAG34925.1 - 5.8e-19 69.4 14.9 5.8e-19 69.4 14.9 7.0 2 2 4 6 6 6 1 AAA domain AAA_21 PF13304.6 OAG34925.1 - 3.4e-14 53.4 13.4 5.4e-08 33.0 0.3 3.8 2 2 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 OAG34925.1 - 1.7e-10 41.2 59.6 2e-10 41.0 15.5 4.5 2 2 0 2 2 2 1 AAA ATPase domain Spc7 PF08317.11 OAG34925.1 - 0.00068 18.6 21.0 0.00068 18.6 21.0 6.6 2 2 6 8 8 8 2 Spc7 kinetochore protein ABC_tran_CTD PF16326.5 OAG34925.1 - 0.002 18.3 4.1 0.002 18.3 4.1 10.2 6 2 5 11 11 11 1 ABC transporter C-terminal domain AAA_29 PF13555.6 OAG34925.1 - 0.02 14.6 0.0 0.048 13.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Val_tRNA-synt_C PF10458.9 OAG34925.1 - 0.17 12.2 0.1 0.17 12.2 0.1 8.6 7 1 1 8 8 8 0 Valyl tRNA synthetase tRNA binding arm Peptidase_M24 PF00557.24 OAG34926.1 - 1.7e-39 135.7 0.2 2.4e-39 135.2 0.2 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF3323 PF11796.8 OAG34926.1 - 0.13 12.2 1.5 0.22 11.4 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function N-terminus (DUF3323) MRJP PF03022.16 OAG34927.1 - 1e-22 80.8 0.0 1.7e-22 80.1 0.0 1.3 1 0 0 1 1 1 1 Major royal jelly protein Arylesterase PF01731.20 OAG34927.1 - 0.032 14.4 0.3 2.1 8.6 0.0 2.8 3 0 0 3 3 3 0 Arylesterase Metallopep PF12044.8 OAG34928.1 - 4.3e-163 542.9 0.0 5.3e-163 542.6 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Reprolysin_5 PF13688.6 OAG34928.1 - 0.034 14.3 1.0 0.11 12.6 1.1 1.8 1 1 0 1 1 1 0 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 OAG34928.1 - 0.069 13.0 0.1 0.14 12.0 0.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Whi5 PF08528.11 OAG34929.1 - 1.3e-06 27.9 0.0 2.7e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 Whi5 like PDCD2_C PF04194.13 OAG34930.1 - 2.8e-47 161.0 0.0 2.9e-45 154.5 0.0 2.3 2 0 0 2 2 2 2 Programmed cell death protein 2, C-terminal putative domain Peptidase_S41_N PF11918.8 OAG34930.1 - 0.029 14.6 0.0 0.062 13.5 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of Peptidase_S41 in eukaryotic IRBP Glyco_trans_2_3 PF13632.6 OAG34933.1 - 2e-51 174.7 1.3 2e-51 174.7 1.3 2.3 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 OAG34933.1 - 2.8e-05 24.0 0.0 0.00037 20.3 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 OAG34933.1 - 0.048 13.5 0.0 0.08 12.8 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Ten1 PF12658.7 OAG34934.1 - 1.1e-31 109.3 0.0 1.2e-31 109.1 0.0 1.0 1 0 0 1 1 1 1 Telomere capping, CST complex subunit Ten1_2 PF15490.6 OAG34934.1 - 0.0065 16.2 0.0 0.0079 15.9 0.0 1.2 1 0 0 1 1 1 1 Telomere-capping, CST complex subunit Snf7 PF03357.21 OAG34935.1 - 1.1e-34 119.6 20.3 1.1e-34 119.6 20.3 2.0 1 1 1 2 2 2 1 Snf7 DUF3138 PF11336.8 OAG34935.1 - 0.21 10.1 13.9 0.25 9.9 12.3 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3138) Allexi_40kDa PF05549.11 OAG34935.1 - 1.6 8.2 6.3 1.7 8.1 5.1 1.6 1 1 1 2 2 2 0 Allexivirus 40kDa protein PIN_8 PF18476.1 OAG34935.1 - 3 7.7 11.7 23 4.8 11.7 2.0 1 1 0 1 1 1 0 PIN like domain SlyX PF04102.12 OAG34935.1 - 6.6 7.4 16.6 2.2 9.0 1.3 3.9 2 1 1 3 3 3 0 SlyX DNA_pol_A_exo1 PF01612.20 OAG34937.1 - 6.5e-38 130.2 0.4 1e-37 129.5 0.4 1.3 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.12 OAG34937.1 - 1.9e-26 92.5 0.9 1.2e-25 90.0 1.1 2.3 2 0 0 2 2 2 1 PMC2NT (NUC016) domain HRDC PF00570.23 OAG34937.1 - 3.1e-13 49.5 0.0 7.9e-13 48.2 0.0 1.8 1 0 0 1 1 1 1 HRDC domain FAD_binding_3 PF01494.19 OAG34939.1 - 6.6e-20 71.6 0.0 1.4e-19 70.6 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 OAG34939.1 - 4.8e-05 23.5 0.1 0.00011 22.4 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAG34939.1 - 0.0057 15.9 0.0 0.0074 15.5 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OAG34939.1 - 0.0075 15.4 0.1 0.16 10.9 0.0 2.3 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.17 OAG34939.1 - 0.019 14.2 0.0 0.031 13.5 0.0 1.2 1 0 0 1 1 1 0 Thi4 family SE PF08491.10 OAG34939.1 - 0.031 13.3 0.0 0.3 10.1 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase DAO PF01266.24 OAG34939.1 - 0.041 13.4 0.2 0.26 10.9 0.1 2.1 1 1 1 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 OAG34939.1 - 0.11 11.7 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAG34939.1 - 0.11 11.1 0.0 0.36 9.5 0.0 1.7 2 0 0 2 2 2 0 HI0933-like protein FMN_red PF03358.15 OAG34940.1 - 2.1e-30 105.5 0.0 2.9e-30 105.1 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 OAG34940.1 - 1.2e-07 31.6 0.0 1.6e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold MFS_1 PF07690.16 OAG34941.1 - 6.1e-37 127.4 23.0 6.1e-37 127.4 23.0 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG34941.1 - 4.4e-10 39.0 23.9 7.7e-09 34.9 23.8 2.8 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 OAG34941.1 - 1.8e-05 23.4 4.3 2.6e-05 22.9 4.3 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) PTR2 PF00854.21 OAG34941.1 - 0.0035 16.2 1.4 0.0035 16.2 1.4 2.1 2 0 0 2 2 2 1 POT family Fungal_trans PF04082.18 OAG34942.1 - 7.4e-25 87.5 0.7 7.4e-25 87.5 0.7 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG34942.1 - 0.051 13.7 2.9 0.1 12.7 2.9 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Vac_Fusion PF02346.16 OAG34942.1 - 0.081 12.6 0.1 0.25 11.0 0.0 1.9 2 0 0 2 2 2 0 Chordopoxvirus multifunctional envelope protein A27 FAD_binding_3 PF01494.19 OAG34943.1 - 5.9e-24 85.0 0.0 9.3e-24 84.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAG34943.1 - 1.8e-05 24.5 4.5 0.048 13.2 4.4 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG34943.1 - 7.5e-05 22.1 1.5 0.051 12.8 0.9 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAG34943.1 - 0.00012 22.1 1.7 0.035 14.1 0.2 2.6 2 0 0 2 2 2 2 FAD-NAD(P)-binding SE PF08491.10 OAG34943.1 - 0.00014 21.0 0.0 0.00083 18.5 0.0 2.0 1 1 0 1 1 1 1 Squalene epoxidase Trp_halogenase PF04820.14 OAG34943.1 - 0.00036 19.5 2.2 0.18 10.6 0.5 2.3 2 0 0 2 2 2 2 Tryptophan halogenase NAD_binding_8 PF13450.6 OAG34943.1 - 0.0004 20.6 0.3 0.0004 20.6 0.3 2.2 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 OAG34943.1 - 0.0012 18.2 0.3 0.0024 17.2 0.1 1.6 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 OAG34943.1 - 0.029 13.4 0.3 0.047 12.8 0.3 1.3 1 0 0 1 1 1 0 FAD binding domain MCRA PF06100.11 OAG34943.1 - 0.068 11.9 0.7 0.12 11.1 0.7 1.3 1 0 0 1 1 1 0 MCRA family HI0933_like PF03486.14 OAG34943.1 - 0.086 11.5 0.1 0.13 10.9 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein Amidohydro_2 PF04909.14 OAG34944.1 - 3.7e-27 95.8 0.1 4.7e-27 95.5 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase CBM_14 PF01607.24 OAG34945.1 - 6e-09 35.9 4.6 7.2e-09 35.7 3.6 1.7 1 1 0 1 1 1 1 Chitin binding Peritrophin-A domain 2OG-FeII_Oxy_3 PF13640.6 OAG34946.1 - 1e-09 39.1 0.0 1.8e-09 38.4 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pox_C4_C10 PF03336.13 OAG34946.1 - 0.16 11.1 0.0 0.3 10.2 0.0 1.4 1 1 0 1 1 1 0 Poxvirus C4/C10 protein Forkhead PF00250.18 OAG34947.1 - 7.3e-15 55.0 0.0 1.4e-14 54.1 0.0 1.4 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 OAG34947.1 - 1e-06 29.0 0.1 2.3e-06 27.8 0.1 1.6 1 0 0 1 1 1 1 FHA domain FHA_2 PF17913.1 OAG34947.1 - 0.0024 18.1 0.0 0.0052 17.0 0.0 1.5 1 0 0 1 1 1 1 FHA domain Gal11_ABD1 PF18535.1 OAG34947.1 - 1.1 9.3 4.0 85 3.3 0.0 2.5 2 0 0 2 2 2 0 Gal11 activator-binding domain (ABD1) Prenylcys_lyase PF07156.14 OAG34948.1 - 7.2e-81 272.1 0.0 1.4e-80 271.1 0.0 1.5 1 1 0 1 1 1 1 Prenylcysteine lyase NAD_binding_8 PF13450.6 OAG34948.1 - 5.9e-10 39.2 0.0 1.3e-09 38.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 OAG34948.1 - 3.9e-09 36.3 0.0 1.5e-08 34.4 0.0 1.8 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 OAG34948.1 - 0.0013 18.8 0.0 0.0027 17.7 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding DAO PF01266.24 OAG34948.1 - 0.0035 17.0 0.0 0.17 11.4 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG34948.1 - 0.017 14.4 0.0 0.34 10.1 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Nuc_deoxyrib_tr PF05014.15 OAG34950.1 - 6e-11 42.5 0.1 1.5e-10 41.2 0.0 1.8 2 0 0 2 2 2 1 Nucleoside 2-deoxyribosyltransferase adh_short_C2 PF13561.6 OAG34951.1 - 9.5e-30 103.9 0.0 1.2e-29 103.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG34951.1 - 9.7e-23 80.6 0.0 1.3e-22 80.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG34951.1 - 1.1e-08 35.2 0.0 2.1e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 KR domain ADH_N PF08240.12 OAG34953.1 - 2.5e-28 98.2 0.7 3.9e-28 97.5 0.7 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG34953.1 - 3.9e-22 78.6 0.1 6.1e-22 78.0 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAG34953.1 - 7.7e-06 27.0 0.1 1.2e-05 26.3 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 OAG34953.1 - 0.0033 16.8 0.2 0.0065 15.8 0.2 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Aldedh PF00171.22 OAG34954.1 - 1.1e-131 439.5 0.1 1.3e-131 439.4 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 OAG34954.1 - 0.02 14.3 0.1 0.13 11.7 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1487) Peptidase_M24 PF00557.24 OAG34955.1 - 6.9e-52 176.2 0.1 1.1e-51 175.6 0.1 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 OAG34955.1 - 4.2e-25 87.9 0.0 7.9e-25 87.0 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain adh_short_C2 PF13561.6 OAG34956.1 - 5.7e-52 176.6 2.2 1.5e-25 90.2 0.2 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG34956.1 - 1.2e-40 139.1 2.5 9.4e-26 90.5 0.0 2.0 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 OAG34956.1 - 5.7e-09 36.1 0.1 9e-09 35.5 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG34956.1 - 1.1e-05 25.1 0.1 1.6e-05 24.5 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 OAG34956.1 - 0.0019 18.4 0.0 0.0034 17.6 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain GDP_Man_Dehyd PF16363.5 OAG34956.1 - 0.021 14.2 0.0 0.029 13.8 0.0 1.1 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase 3HCDH_N PF02737.18 OAG34956.1 - 0.032 14.1 0.0 0.052 13.4 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HHH_5 PF14520.6 OAG34956.1 - 0.13 12.9 0.1 0.25 12.0 0.1 1.4 1 0 0 1 1 1 0 Helix-hairpin-helix domain adh_short_C2 PF13561.6 OAG34957.1 - 3.8e-35 121.5 2.7 3.6e-23 82.3 0.0 3.2 2 1 1 3 3 3 3 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG34957.1 - 2.5e-33 115.2 0.1 3.2e-32 111.6 0.1 2.2 1 1 0 1 1 1 1 short chain dehydrogenase Cyclase PF04199.13 OAG34957.1 - 9.5e-14 51.8 0.0 1.9e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 Putative cyclase KR PF08659.10 OAG34957.1 - 4.2e-10 39.8 0.0 1.2e-05 25.3 0.0 2.2 2 0 0 2 2 2 2 KR domain TauD PF02668.16 OAG34958.1 - 2.3e-52 178.5 0.2 2.7e-52 178.2 0.2 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Fungal_trans PF04082.18 OAG34959.1 - 5.3e-10 38.8 2.0 7.2e-10 38.3 0.6 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG34959.1 - 6.2e-05 23.0 13.1 0.00011 22.2 11.6 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HpcH_HpaI PF03328.14 OAG34960.1 - 6.7e-35 120.2 0.0 8.5e-35 119.9 0.0 1.0 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family Sugar_tr PF00083.24 OAG34961.1 - 6.9e-82 275.7 27.7 8.1e-82 275.5 27.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG34961.1 - 1.9e-25 89.6 38.9 1.4e-22 80.1 30.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Abhydrolase_1 PF00561.20 OAG34962.1 - 1.8e-21 76.9 0.0 3.6e-21 76.0 0.0 1.4 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG34962.1 - 8.1e-14 52.8 0.2 9.9e-14 52.5 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG34962.1 - 0.00032 20.0 0.0 0.00053 19.3 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 EHN PF06441.12 OAG34962.1 - 0.01 16.2 0.1 0.02 15.2 0.1 1.5 1 0 0 1 1 1 0 Epoxide hydrolase N terminus Herpes_LMP1 PF05297.11 OAG34963.1 - 3 6.9 6.1 4 6.5 6.1 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) RIC3 PF15361.6 OAG34963.1 - 3.2 8.1 0.0 3.2 8.1 0.0 2.3 2 1 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 Fungal_trans PF04082.18 OAG34964.1 - 8.5e-19 67.6 0.1 1.9e-18 66.5 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 OAG34965.1 - 2e-19 69.7 13.2 2e-19 69.7 13.2 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Vut_1 PF02592.15 OAG34965.1 - 0.12 12.7 6.1 0.39 11.0 0.3 2.7 2 1 0 2 2 2 0 Putative vitamin uptake transporter PAF-AH_p_II PF03403.13 OAG34966.1 - 1.3e-41 142.4 0.0 6.4e-40 136.8 0.0 2.0 1 1 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 OAG34966.1 - 3.1e-06 26.3 0.1 3.8e-05 22.7 0.1 2.1 1 1 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 OAG34966.1 - 2.5e-05 23.7 0.6 0.011 15.0 0.0 2.7 2 1 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OAG34966.1 - 0.001 19.7 0.1 0.0033 18.0 0.0 1.7 2 1 0 2 2 2 1 Alpha/beta hydrolase family Chlorophyllase PF07224.11 OAG34966.1 - 0.034 13.2 0.0 0.077 12.0 0.0 1.5 1 0 0 1 1 1 0 Chlorophyllase FAD_binding_3 PF01494.19 OAG34967.1 - 2.4e-20 73.1 0.0 3.1e-20 72.7 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAG34967.1 - 0.00014 21.6 4.0 0.0035 17.0 2.4 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 OAG34967.1 - 0.00025 21.1 1.9 0.027 14.5 0.1 2.7 3 0 0 3 3 3 2 FAD-NAD(P)-binding SE PF08491.10 OAG34967.1 - 0.00037 19.7 0.0 0.0034 16.5 0.0 2.1 1 1 0 1 1 1 1 Squalene epoxidase NAD_binding_8 PF13450.6 OAG34967.1 - 0.002 18.3 0.1 0.002 18.3 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAG34967.1 - 0.0082 15.4 2.2 0.89 8.7 1.6 2.7 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 OAG34967.1 - 0.02 13.8 0.6 0.91 8.3 0.2 2.3 2 0 0 2 2 2 0 Tryptophan halogenase Amino_oxidase PF01593.24 OAG34967.1 - 0.12 11.6 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase eIF3_N PF09440.10 OAG34967.1 - 0.12 12.8 0.0 0.51 10.8 0.0 1.9 2 0 0 2 2 2 0 eIF3 subunit 6 N terminal domain MFS_1 PF07690.16 OAG34968.1 - 2.2e-28 99.2 27.2 2.2e-28 99.2 27.2 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 OAG34969.1 - 2.2e-17 63.0 23.3 3.1e-17 62.6 23.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily TauD PF02668.16 OAG34970.1 - 1.2e-45 156.4 0.2 1.7e-45 155.9 0.2 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Sas10 PF09368.10 OAG34971.1 - 7.6e-30 103.2 7.8 7.6e-30 103.2 7.8 3.4 4 0 0 4 4 4 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 OAG34971.1 - 2e-11 44.4 0.0 2e-11 44.4 0.0 3.0 2 1 0 2 2 2 1 Sas10/Utp3/C1D family APH PF01636.23 OAG34973.1 - 6.1e-13 49.2 0.2 4.2e-08 33.4 0.1 2.1 2 0 0 2 2 2 2 Phosphotransferase enzyme family DUF1679 PF07914.11 OAG34973.1 - 7.8e-07 28.3 0.1 0.00023 20.2 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1679) Choline_kinase PF01633.20 OAG34973.1 - 0.0006 19.5 0.0 0.00095 18.8 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase adh_short PF00106.25 OAG34974.1 - 1.2e-19 70.6 0.0 3.7e-19 69.0 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG34974.1 - 6.5e-10 39.0 0.0 6.5e-09 35.7 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG34974.1 - 1.4e-06 28.4 0.0 0.00036 20.5 0.0 2.1 1 1 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 OAG34974.1 - 0.02 14.2 0.1 0.033 13.5 0.1 1.2 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DFP PF04127.15 OAG34974.1 - 0.043 13.6 0.2 0.073 12.9 0.2 1.4 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Glyco_transf_4 PF13439.6 OAG34974.1 - 0.077 13.0 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase Family 4 ADH_zinc_N PF00107.26 OAG34974.1 - 0.11 12.5 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase LytR_C PF13399.6 OAG34974.1 - 0.11 13.4 0.9 1.3 10.1 0.1 2.4 2 1 0 2 2 2 0 LytR cell envelope-related transcriptional attenuator MutS_V PF00488.21 OAG34975.1 - 1e-53 182.2 0.1 1.7e-53 181.4 0.1 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 OAG34975.1 - 1.6e-21 77.5 0.1 3.6e-21 76.3 0.0 1.7 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.18 OAG34975.1 - 0.0036 17.6 0.0 0.007 16.7 0.0 1.5 1 0 0 1 1 1 1 MutS family domain IV Herpes_UL14 PF03580.14 OAG34975.1 - 0.029 14.6 0.2 0.077 13.2 0.2 1.7 1 0 0 1 1 1 0 Herpesvirus UL14-like protein FA_desaturase PF00487.24 OAG34976.1 - 4e-26 92.4 10.7 6.4e-26 91.7 10.7 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.10 OAG34976.1 - 5.1e-15 54.7 0.2 8.7e-15 53.9 0.2 1.4 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) Peptidase_M8 PF01457.16 OAG34976.1 - 0.16 10.6 0.1 0.27 9.9 0.1 1.2 1 0 0 1 1 1 0 Leishmanolysin UBX PF00789.20 OAG34980.1 - 9.6e-06 25.7 0.0 2.7e-05 24.3 0.0 1.8 1 0 0 1 1 1 1 UBX domain UBA PF00627.31 OAG34980.1 - 0.00022 21.1 0.0 0.00049 19.9 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain zf-C2H2_2 PF12756.7 OAG34980.1 - 0.2 12.0 0.1 0.2 12.0 0.1 1.7 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2HE PF16278.5 OAG34980.1 - 0.55 10.7 0.1 0.55 10.7 0.1 3.1 2 1 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger RR_TM4-6 PF06459.12 OAG34980.1 - 0.86 9.4 23.5 1.3 8.8 23.5 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Utp11 PF03998.13 OAG34980.1 - 1 9.2 25.4 1.5 8.7 25.4 1.2 1 0 0 1 1 1 0 Utp11 protein SOBP PF15279.6 OAG34980.1 - 2 9.0 5.7 2.5 8.6 5.7 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Hamartin PF04388.12 OAG34980.1 - 6.5 5.3 12.8 7.7 5.0 12.8 1.1 1 0 0 1 1 1 0 Hamartin protein Motile_Sperm PF00635.26 OAG34981.1 - 5.8e-27 93.7 0.1 1.4e-26 92.4 0.1 1.7 1 0 0 1 1 1 1 MSP (Major sperm protein) domain GAS PF13851.6 OAG34981.1 - 0.0093 15.3 3.4 0.015 14.7 3.4 1.3 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding T3SS_needle_E PF08988.10 OAG34981.1 - 0.0094 16.1 3.3 0.019 15.1 3.3 1.5 1 0 0 1 1 1 1 Type III secretion system, cytoplasmic E component of needle FlxA PF14282.6 OAG34981.1 - 0.012 15.6 9.6 0.025 14.6 9.6 1.4 1 0 0 1 1 1 0 FlxA-like protein Ndc1_Nup PF09531.10 OAG34981.1 - 0.014 14.1 7.2 0.019 13.7 7.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Phage_GP20 PF06810.11 OAG34981.1 - 0.017 14.9 1.3 0.03 14.1 1.3 1.4 1 0 0 1 1 1 0 Phage minor structural protein GP20 COG5 PF10392.9 OAG34981.1 - 0.02 15.1 1.9 0.032 14.4 1.9 1.4 1 0 0 1 1 1 0 Golgi transport complex subunit 5 ASH PF15780.5 OAG34981.1 - 0.024 14.8 1.1 0.045 14.0 0.0 2.0 2 0 0 2 2 2 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Sas10_Utp3 PF04000.15 OAG34981.1 - 0.024 15.2 0.3 0.073 13.7 0.3 1.8 1 0 0 1 1 1 0 Sas10/Utp3/C1D family Sec2p PF06428.11 OAG34981.1 - 0.044 13.8 3.1 0.097 12.7 2.8 1.7 1 1 0 1 1 1 0 GDP/GTP exchange factor Sec2p PDGLE PF13190.6 OAG34981.1 - 0.045 13.6 0.1 0.084 12.8 0.1 1.5 1 0 0 1 1 1 0 PDGLE domain PspA_IM30 PF04012.12 OAG34981.1 - 0.046 13.3 11.0 0.075 12.6 11.0 1.3 1 0 0 1 1 1 0 PspA/IM30 family DotU PF09850.9 OAG34981.1 - 0.072 12.8 0.3 0.43 10.3 0.2 2.0 2 0 0 2 2 2 0 Type VI secretion system protein DotU eIF3_N PF09440.10 OAG34981.1 - 0.14 12.6 1.5 0.28 11.6 1.5 1.5 1 0 0 1 1 1 0 eIF3 subunit 6 N terminal domain ATG16 PF08614.11 OAG34981.1 - 0.15 12.2 7.8 0.21 11.8 7.8 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Spectrin PF00435.21 OAG34981.1 - 0.2 12.2 4.3 0.19 12.2 2.7 1.8 2 0 0 2 2 1 0 Spectrin repeat GAT PF03127.14 OAG34981.1 - 0.33 11.3 1.8 0.89 9.9 1.8 1.6 1 0 0 1 1 1 0 GAT domain ABC_tran_CTD PF16326.5 OAG34981.1 - 0.45 10.8 5.7 0.85 9.9 5.7 1.4 1 0 0 1 1 1 0 ABC transporter C-terminal domain Swi5 PF07061.11 OAG34981.1 - 0.73 10.0 3.4 1.9 8.6 3.4 1.7 1 0 0 1 1 1 0 Swi5 Phage_GPO PF05929.11 OAG34981.1 - 0.99 9.0 8.8 1.5 8.4 8.4 1.3 1 1 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase OmpH PF03938.14 OAG34981.1 - 1.5 9.1 10.5 1.5 9.1 8.8 1.8 2 1 1 3 3 2 0 Outer membrane protein (OmpH-like) Flagellin_N PF00669.20 OAG34981.1 - 1.6 8.8 10.4 2.9 8.0 10.4 1.3 1 0 0 1 1 1 0 Bacterial flagellin N-terminal helical region RRM_1 PF00076.22 OAG34982.1 - 3.6e-16 58.7 0.0 6.1e-16 58.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OAG34982.1 - 0.0018 17.9 0.0 0.0027 17.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 OAG34982.1 - 0.0052 16.8 0.0 0.0094 16.0 0.0 1.4 1 0 0 1 1 1 1 RNA binding motif Corona_nucleoca PF00937.18 OAG34982.1 - 0.072 12.1 12.6 0.13 11.3 12.6 1.3 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein AF-4 PF05110.13 OAG34982.1 - 0.22 9.6 5.4 1.3 7.0 1.0 2.0 2 0 0 2 2 2 0 AF-4 proto-oncoprotein PRP38_assoc PF12871.7 OAG34982.1 - 2.3 8.9 35.1 0.15 12.7 28.8 2.0 2 0 0 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term DUF3176 PF11374.8 OAG34987.1 - 9.1e-18 64.4 2.9 1.7e-17 63.6 2.9 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) Mito_carr PF00153.27 OAG34988.1 - 2.6e-45 152.3 7.3 2.4e-16 59.4 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Fungal_trans PF04082.18 OAG34989.1 - 2e-24 86.1 0.0 3.3e-24 85.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG34989.1 - 2.6e-11 43.5 12.6 4.7e-11 42.6 12.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.24 OAG34990.1 - 1e-100 337.8 12.7 1.2e-100 337.5 12.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG34990.1 - 2.6e-25 89.1 19.1 2.6e-25 89.1 19.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 OAG34990.1 - 7.7e-05 21.3 1.2 0.00016 20.2 1.2 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2929 PF11151.8 OAG34990.1 - 0.0031 17.8 1.5 0.16 12.3 1.7 3.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2929) SERTA PF06031.13 OAG34990.1 - 0.077 12.7 0.7 0.14 11.9 0.1 1.7 2 0 0 2 2 2 0 SERTA motif SPC25 PF06703.11 OAG34990.1 - 3.3 7.5 5.1 0.34 10.7 0.2 1.9 2 1 1 3 3 3 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Ras PF00071.22 OAG34992.1 - 6.6e-56 188.4 0.0 7.6e-56 188.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAG34992.1 - 1.5e-21 76.8 0.0 2.3e-21 76.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAG34992.1 - 1.9e-08 34.0 0.0 2.3e-08 33.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OAG34992.1 - 0.0027 17.3 0.0 0.0069 15.9 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain RRM_1 PF00076.22 OAG34993.1 - 5.5e-17 61.4 0.1 1.2e-16 60.3 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.25 OAG34994.1 - 2.7e-40 138.4 0.0 4.9e-40 137.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG34994.1 - 4e-28 98.4 0.0 5.5e-28 97.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OAG34994.1 - 0.0005 19.5 0.0 0.00095 18.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OAG34994.1 - 0.014 15.3 0.0 4.4 7.2 0.0 2.9 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kinase-like PF14531.6 OAG34994.1 - 0.025 13.9 0.0 0.039 13.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Med10 PF09748.9 OAG34995.1 - 9.4e-34 116.0 0.1 1.4e-33 115.5 0.1 1.2 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex Chalcone_2 PF16035.5 OAG34996.1 - 2.9e-75 252.5 0.0 3.9e-75 252.1 0.0 1.2 1 0 0 1 1 1 1 Chalcone isomerase like Chalcone_3 PF16036.5 OAG34996.1 - 0.0016 18.6 0.0 0.04 14.0 0.0 2.3 2 0 0 2 2 2 1 Chalcone isomerase-like Glutaredoxin PF00462.24 OAG34997.1 - 1.7e-18 66.6 0.0 2.4e-18 66.1 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_3 PF13192.6 OAG34997.1 - 0.0044 17.0 0.0 0.0065 16.5 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_2 PF13098.6 OAG34997.1 - 0.014 15.8 0.2 0.033 14.6 0.2 1.8 1 1 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_4 PF13462.6 OAG34997.1 - 0.02 15.0 0.7 2.2 8.4 0.3 2.1 1 1 1 2 2 2 0 Thioredoxin DUF836 PF05768.14 OAG34997.1 - 0.028 14.8 0.1 0.04 14.3 0.1 1.5 1 1 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Thioredoxin PF00085.20 OAG34997.1 - 0.03 14.3 0.0 0.031 14.3 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin DSBA PF01323.20 OAG34997.1 - 0.042 13.6 0.1 0.37 10.5 0.1 2.0 1 1 1 2 2 2 0 DSBA-like thioredoxin domain TraF PF13728.6 OAG34997.1 - 0.14 11.9 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein DnaJ PF00226.31 OAG34999.1 - 1.1e-20 73.5 1.5 2.8e-20 72.2 1.5 1.7 1 0 0 1 1 1 1 DnaJ domain Cellulase PF00150.18 OAG35000.1 - 1.1e-07 31.5 0.0 2.4e-07 30.5 0.0 1.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Stathmin PF00836.19 OAG35000.1 - 0.19 11.7 0.0 0.37 10.8 0.0 1.4 1 0 0 1 1 1 0 Stathmin family Myotub-related PF06602.14 OAG35001.1 - 1.3e-149 497.9 0.0 1.7e-149 497.5 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain GRAM PF02893.20 OAG35001.1 - 0.024 14.5 0.0 0.053 13.4 0.0 1.5 1 0 0 1 1 1 0 GRAM domain DSPc PF00782.20 OAG35002.1 - 2e-21 76.2 0.0 4.9e-20 71.7 0.0 2.3 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Peptidase_M15 PF01427.17 OAG35003.1 - 0.076 12.7 0.0 0.083 12.6 0.0 1.1 1 0 0 1 1 1 0 D-ala-D-ala dipeptidase Metallophos PF00149.28 OAG35005.1 - 1.9e-11 44.9 0.2 3.3e-11 44.1 0.2 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OAG35005.1 - 7.5e-06 26.2 0.1 0.00019 21.7 0.1 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain CDO_I PF05995.12 OAG35006.1 - 1e-42 145.3 0.0 1.4e-42 144.9 0.0 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I PCO_ADO PF07847.12 OAG35006.1 - 0.00046 19.7 0.0 0.00073 19.0 0.0 1.2 1 0 0 1 1 1 1 PCO_ADO MMR_HSR1_Xtn PF16897.5 OAG35007.1 - 6.4e-41 138.7 1.2 3.5e-40 136.3 0.4 2.2 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 OAG35007.1 - 3.6e-23 81.4 0.1 7.1e-23 80.4 0.1 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 OAG35007.1 - 1.7e-20 73.2 0.0 6.5e-20 71.3 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OAG35007.1 - 7.3e-09 35.3 0.1 4.5e-08 32.8 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 OAG35007.1 - 0.0005 19.7 0.0 4.4 6.8 0.0 3.7 2 2 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 OAG35007.1 - 0.0016 18.6 0.0 0.36 10.9 0.0 2.4 2 0 0 2 2 2 2 Dynamin family MeaB PF03308.16 OAG35007.1 - 0.0052 15.8 0.6 0.018 14.0 0.1 2.0 2 1 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_GTPase PF03193.16 OAG35007.1 - 0.12 12.3 0.8 3.5 7.5 0.1 2.8 2 1 1 3 3 3 0 RsgA GTPase HTH_Tnp_Tc5 PF03221.16 OAG35008.1 - 3.1e-11 43.1 0.2 5.7e-11 42.3 0.2 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 OAG35008.1 - 0.00039 20.0 1.3 0.00039 20.0 1.3 2.6 2 1 1 3 3 3 1 CENP-B N-terminal DNA-binding domain MarR PF01047.22 OAG35008.1 - 0.0032 17.3 0.0 0.0079 16.1 0.0 1.6 1 0 0 1 1 1 1 MarR family HTH_38 PF13936.6 OAG35008.1 - 0.012 15.4 0.6 0.023 14.5 0.6 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_23 PF13384.6 OAG35008.1 - 0.044 13.6 0.1 0.28 11.0 0.0 2.3 2 0 0 2 2 2 0 Homeodomain-like domain Sigma70_r4 PF04545.16 OAG35008.1 - 0.062 12.8 0.2 0.12 12.0 0.2 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 DUF3602 PF12223.8 OAG35009.1 - 5.3e-17 62.2 17.4 2.4e-14 53.7 1.4 3.0 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) hDGE_amylase PF14701.6 OAG35010.1 - 1.5e-170 568.1 0.0 2e-170 567.6 0.0 1.2 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain GDE_C PF06202.14 OAG35010.1 - 7.2e-118 393.8 0.0 1.2e-117 393.1 0.0 1.3 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase DAHP_synth_1 PF00793.20 OAG35010.1 - 7.2e-102 339.9 0.0 7.4e-101 336.6 0.0 2.1 2 0 0 2 2 2 1 DAHP synthetase I family hGDE_central PF14702.6 OAG35010.1 - 3.7e-85 285.6 0.0 7e-85 284.7 0.0 1.5 1 0 0 1 1 1 1 Central domain of human glycogen debranching enzyme hGDE_N PF14699.6 OAG35010.1 - 2.9e-30 104.2 0.0 5.8e-30 103.3 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.24 OAG35010.1 - 0.044 13.3 0.0 0.087 12.4 0.0 1.4 1 0 0 1 1 1 0 Alpha amylase, catalytic domain SMYLE_N PF18615.1 OAG35012.1 - 5.1 6.5 8.5 12 5.4 8.5 1.6 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain Glyco_trans_2_3 PF13632.6 OAG35013.1 - 1.8e-16 60.6 0.9 1.8e-16 60.6 0.9 1.8 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Cellulase PF00150.18 OAG35014.1 - 2e-29 102.9 0.1 2.4e-29 102.6 0.1 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Peptidase_M19 PF01244.21 OAG35015.1 - 4.3e-91 305.4 0.0 5.2e-91 305.1 0.0 1.1 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) DSBA PF01323.20 OAG35016.1 - 3.3e-16 59.6 0.0 3.8e-16 59.4 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain adh_short PF00106.25 OAG35017.1 - 2.7e-36 124.9 0.0 3.5e-36 124.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG35017.1 - 3.7e-27 95.4 0.0 4.6e-27 95.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 3HCDH_N PF02737.18 OAG35017.1 - 0.00083 19.3 0.0 0.0012 18.8 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain KR PF08659.10 OAG35017.1 - 0.0057 16.6 0.0 0.012 15.5 0.1 1.6 1 1 0 1 1 1 1 KR domain F420_oxidored PF03807.17 OAG35017.1 - 0.021 15.4 0.2 0.051 14.1 0.1 1.7 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Polysacc_synt_2 PF02719.15 OAG35017.1 - 0.07 12.2 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Shikimate_DH PF01488.20 OAG35017.1 - 0.074 13.1 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NMO PF03060.15 OAG35018.1 - 2.2e-53 181.8 2.7 4.4e-52 177.5 2.7 2.0 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 OAG35018.1 - 5.9e-13 48.5 0.0 1.3e-10 40.9 0.0 2.1 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 OAG35018.1 - 0.0036 16.4 0.4 0.0055 15.8 0.4 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Acyl-CoA_dh_1 PF00441.24 OAG35019.1 - 1.9e-35 122.3 1.0 2.9e-35 121.7 1.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.28 OAG35019.1 - 2.6e-17 62.7 0.0 5.7e-17 61.6 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.19 OAG35019.1 - 9.2e-15 54.6 0.2 1.7e-14 53.8 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 OAG35019.1 - 8e-07 29.4 0.0 1.5e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 OAG35019.1 - 0.013 16.1 0.1 0.26 11.9 0.1 2.5 1 1 0 1 1 1 0 Acyl-CoA dehydrogenase, N-terminal domain HET PF06985.11 OAG35020.1 - 9.7e-26 90.9 0.1 1.6e-25 90.2 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ThiF PF00899.21 OAG35021.1 - 4.4e-52 176.9 0.0 2.1e-51 174.7 0.0 1.9 2 0 0 2 2 2 1 ThiF family NAD_Gly3P_dh_N PF01210.23 OAG35021.1 - 1e-43 149.0 0.0 3.4e-43 147.3 0.0 1.8 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 OAG35021.1 - 1.2e-43 148.8 0.0 2.4e-43 147.8 0.0 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus Rhodanese PF00581.20 OAG35021.1 - 0.019 15.5 0.0 0.42 11.1 0.0 2.7 1 1 0 1 1 1 0 Rhodanese-like domain NAD_binding_7 PF13241.6 OAG35021.1 - 0.027 14.9 0.2 3 8.4 0.0 3.1 2 1 0 2 2 2 0 Putative NAD(P)-binding ATP-synt_S1 PF05827.12 OAG35022.1 - 1.7e-05 24.6 0.0 2.7e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) Iso_dh PF00180.20 OAG35023.1 - 3.3e-97 325.7 0.0 8.3e-97 324.4 0.0 1.5 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Glyco_hydro_17 PF00332.18 OAG35025.1 - 2.3e-05 24.1 0.3 4.3e-05 23.2 0.3 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 FtsX_ECD PF18075.1 OAG35025.1 - 0.06 14.0 0.0 11 6.8 0.0 2.3 1 1 1 2 2 2 0 FtsX extracellular domain FAT PF02259.23 OAG35026.1 - 0.035 13.3 0.0 0.045 13.0 0.0 1.2 1 0 0 1 1 1 0 FAT domain Nup54_C PF18437.1 OAG35026.1 - 0.17 11.8 0.4 0.4 10.6 0.4 1.6 1 0 0 1 1 1 0 Nup54 C-terminal interacting domain DUF3506 PF12014.8 OAG35027.1 - 1.7e-54 183.6 0.0 3.1e-54 182.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3506) F-box-like PF12937.7 OAG35027.1 - 1.1e-09 38.0 3.3 2.4e-09 36.9 3.3 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAG35027.1 - 2.4e-06 27.3 3.7 2.4e-06 27.3 3.7 1.7 2 0 0 2 2 2 1 F-box domain F-box_4 PF15966.5 OAG35027.1 - 0.024 14.5 0.1 0.046 13.6 0.1 1.4 1 0 0 1 1 1 0 F-box Elongin_A PF06881.11 OAG35027.1 - 0.049 14.2 0.0 0.62 10.6 0.0 2.2 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A PK PF00224.21 OAG35028.1 - 1.1e-169 563.9 4.1 1.3e-169 563.6 4.1 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 OAG35028.1 - 4.2e-37 127.0 0.0 1.2e-36 125.5 0.0 1.8 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 OAG35028.1 - 0.00063 18.9 0.2 0.0021 17.2 0.1 1.8 1 1 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.25 OAG35028.1 - 0.002 17.2 0.0 0.021 13.8 0.0 2.1 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain AMIN PF11741.8 OAG35028.1 - 0.27 11.4 1.6 0.7 10.1 0.5 2.2 2 0 0 2 2 2 0 AMIN domain RhoGAP PF00620.27 OAG35029.1 - 2.2e-15 56.8 0.0 6.7e-15 55.2 0.0 1.8 1 0 0 1 1 1 1 RhoGAP domain DEP PF00610.21 OAG35029.1 - 3.6e-10 39.7 0.0 8e-10 38.6 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) FCH PF00611.23 OAG35029.1 - 1.3e-07 31.8 0.0 3.6e-07 30.4 0.0 1.8 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain BAR PF03114.18 OAG35029.1 - 0.078 12.6 3.0 0.07 12.8 0.7 1.9 2 0 0 2 2 2 0 BAR domain CALCOCO1 PF07888.11 OAG35030.1 - 2.8e-05 23.2 3.1 2.8e-05 23.2 3.1 2.9 2 1 0 2 2 2 1 Calcium binding and coiled-coil domain (CALCOCO1) like Hydantoinase_B PF02538.14 OAG35030.1 - 2 6.7 4.4 3.6 5.9 4.4 1.4 1 0 0 1 1 1 0 Hydantoinase B/oxoprolinase FMO-like PF00743.19 OAG35031.1 - 2e-20 72.7 0.0 5.7e-18 64.6 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 OAG35031.1 - 2.9e-11 43.1 0.1 1.1e-08 34.6 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 OAG35031.1 - 1.6e-09 37.9 0.0 4.4e-09 36.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAG35031.1 - 1.9e-06 27.3 0.0 7.1e-05 22.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG35031.1 - 2.7e-06 26.9 0.0 8.4e-05 22.0 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAG35031.1 - 3.2e-06 27.2 0.0 0.00029 20.9 0.0 3.0 3 0 0 3 3 3 1 FAD-NAD(P)-binding Amino_oxidase PF01593.24 OAG35031.1 - 0.026 13.8 0.0 4 6.6 0.0 2.3 2 1 0 2 2 2 0 Flavin containing amine oxidoreductase DALR_1 PF05746.15 OAG35031.1 - 0.055 13.6 0.1 0.13 12.4 0.1 1.6 1 0 0 1 1 1 0 DALR anticodon binding domain Cyclase PF04199.13 OAG35032.1 - 7.8e-15 55.3 0.0 1.2e-14 54.7 0.0 1.4 1 0 0 1 1 1 1 Putative cyclase Fungal_trans PF04082.18 OAG35033.1 - 9.5e-21 74.0 1.9 1.8e-20 73.1 0.8 2.0 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG35033.1 - 3.1e-07 30.4 11.9 5.9e-07 29.5 11.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAG35034.1 - 1.2e-15 57.3 0.4 1.9e-15 56.6 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cep57_CLD PF14073.6 OAG35034.1 - 0.17 11.9 0.2 0.35 10.9 0.2 1.4 1 0 0 1 1 1 0 Centrosome localisation domain of Cep57 Fungal_trans PF04082.18 OAG35035.1 - 2.1e-16 59.8 1.4 5e-16 58.5 1.4 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG35035.1 - 5.9e-08 32.7 12.4 1.3e-07 31.6 12.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyoxalase PF00903.25 OAG35036.1 - 2.5e-12 47.1 0.0 3.6e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 OAG35036.1 - 0.018 15.0 0.0 0.061 13.3 0.0 1.9 1 1 0 1 1 1 0 Glyoxalase-like domain Glyoxalase_6 PF18029.1 OAG35036.1 - 0.023 15.5 0.0 0.04 14.7 0.0 1.4 1 0 0 1 1 1 0 Glyoxalase-like domain p450 PF00067.22 OAG35037.1 - 4.6e-72 243.2 0.0 5.9e-72 242.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF1206 PF06724.11 OAG35037.1 - 0.12 12.5 0.5 0.2 11.8 0.5 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1206) AMP-binding PF00501.28 OAG35038.1 - 5.1e-73 246.1 0.0 6.1e-73 245.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG35038.1 - 2e-16 60.7 0.1 4.5e-16 59.6 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Sugar_tr PF00083.24 OAG35039.1 - 9.3e-87 291.7 19.4 1.1e-86 291.5 19.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG35039.1 - 1.6e-28 99.7 68.7 1.7e-22 79.9 34.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.18 OAG35040.1 - 3.3e-12 46.0 0.8 4.9e-12 45.4 0.8 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF4148 PF13663.6 OAG35041.1 - 0.13 12.5 0.1 3.6 7.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) FMO-like PF00743.19 OAG35042.1 - 1.9e-18 66.2 0.1 7.5e-16 57.6 0.1 2.5 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OAG35042.1 - 2.9e-07 30.6 0.0 1e-06 28.9 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 OAG35042.1 - 0.00022 20.5 0.0 0.12 11.5 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 OAG35042.1 - 0.00023 20.5 0.0 0.0094 15.2 0.0 3.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 OAG35042.1 - 0.00048 20.2 0.0 0.058 13.4 0.0 2.5 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.6 OAG35042.1 - 0.0036 17.3 0.1 0.1 12.6 0.0 2.9 3 0 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.17 OAG35042.1 - 0.026 13.8 0.0 0.34 10.1 0.0 2.4 3 0 0 3 3 3 0 Thi4 family PS_pyruv_trans PF04230.13 OAG35042.1 - 0.13 12.1 0.1 0.25 11.2 0.1 1.5 1 0 0 1 1 1 0 Polysaccharide pyruvyl transferase AMP-binding PF00501.28 OAG35043.1 - 3.5e-83 279.6 0.2 6.1e-83 278.8 0.0 1.4 2 0 0 2 2 2 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG35043.1 - 3e-15 56.9 0.2 7.1e-15 55.8 0.2 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain CoA_transf_3 PF02515.17 OAG35044.1 - 8.3e-38 130.4 0.0 2.8e-32 112.2 0.0 2.4 2 0 0 2 2 2 2 CoA-transferase family III AtuA PF07287.11 OAG35045.1 - 8.6e-120 399.6 0.0 1.1e-119 399.3 0.0 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA Abhydrolase_3 PF07859.13 OAG35046.1 - 8e-31 107.5 0.1 1e-30 107.2 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 OAG35046.1 - 7.1e-12 44.9 0.0 1e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase BAAT_C PF08840.11 OAG35046.1 - 0.16 11.8 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal adh_short PF00106.25 OAG35048.1 - 6.7e-10 38.7 0.0 1.7e-09 37.4 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG35048.1 - 7.1e-09 35.6 0.0 1.2e-08 34.9 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Lactamase_B PF00753.27 OAG35049.1 - 8.6e-08 32.4 0.1 2e-07 31.2 0.0 1.6 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OAG35049.1 - 0.0038 16.8 1.7 0.036 13.6 0.1 2.7 3 1 1 4 4 4 1 Beta-lactamase superfamily domain MFS_1 PF07690.16 OAG35050.1 - 1.4e-38 132.7 52.1 1.3e-37 129.6 52.1 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 OAG35050.1 - 1.4e-07 30.4 25.9 3.6e-07 29.0 25.9 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Fungal_trans_2 PF11951.8 OAG35051.1 - 6.5e-35 120.7 1.4 1.2e-34 119.8 1.4 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Amidase PF01425.21 OAG35052.1 - 3.3e-101 339.5 0.0 4.3e-101 339.1 0.0 1.1 1 0 0 1 1 1 1 Amidase SSF PF00474.17 OAG35053.1 - 1.6e-13 50.4 19.4 2.5e-13 49.7 19.4 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family GTA_holin_3TM PF11351.8 OAG35053.1 - 1 9.9 2.8 3 8.4 2.8 1.8 1 0 0 1 1 1 0 Holin of 3TMs, for gene-transfer release 7tm_7 PF08395.12 OAG35053.1 - 1.7 7.7 6.9 0.17 11.0 0.6 2.4 2 0 0 2 2 2 0 7tm Chemosensory receptor FAD_binding_3 PF01494.19 OAG35054.1 - 1.7e-20 73.5 0.0 2.6e-20 73.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 OAG35054.1 - 4.5e-08 33.2 0.8 1.4e-07 31.6 0.8 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAG35054.1 - 4.3e-07 29.5 0.4 7.8e-07 28.6 0.4 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OAG35054.1 - 1.7e-06 27.3 0.4 2.6e-06 26.8 0.4 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 OAG35054.1 - 2.5e-06 26.8 2.1 3.9e-06 26.2 2.1 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAG35054.1 - 5.7e-06 26.1 6.8 3.4e-05 23.6 5.5 2.2 1 1 1 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 OAG35054.1 - 6.3e-06 25.8 0.1 8.8e-06 25.3 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 OAG35054.1 - 0.00053 19.4 0.3 0.0092 15.3 0.2 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase HI0933_like PF03486.14 OAG35054.1 - 0.0011 17.8 1.5 0.0016 17.2 1.5 1.2 1 0 0 1 1 1 1 HI0933-like protein AlaDh_PNT_C PF01262.21 OAG35054.1 - 0.0018 17.6 0.8 0.0029 16.9 0.8 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 OAG35054.1 - 0.0019 17.3 2.7 0.0031 16.6 2.7 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.27 OAG35054.1 - 0.0033 17.9 0.4 0.0085 16.6 0.4 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.23 OAG35054.1 - 0.16 12.0 0.3 0.26 11.3 0.3 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox_3 PF13738.6 OAG35054.1 - 0.17 11.1 0.3 0.33 10.1 0.3 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 OAG35054.1 - 0.28 11.0 1.0 0.56 10.1 1.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Amidohydro_2 PF04909.14 OAG35055.1 - 3.8e-36 125.4 2.5 2e-35 123.0 2.5 1.9 1 1 0 1 1 1 1 Amidohydrolase Fungal_trans PF04082.18 OAG35056.1 - 8.5e-09 34.8 0.1 2.4e-08 33.4 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF2150 PF09920.9 OAG35056.1 - 0.094 12.7 0.1 0.19 11.7 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2150) PMM PF03332.13 OAG35057.1 - 2.2e-96 321.9 0.0 2.8e-96 321.5 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 OAG35057.1 - 0.042 13.6 0.0 7.4 6.2 0.0 2.1 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase S6PP PF05116.13 OAG35057.1 - 0.25 10.9 0.0 1.8 8.0 0.0 1.9 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase AA_permease PF00324.21 OAG35058.1 - 2.6e-142 474.8 34.4 3.1e-142 474.5 34.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAG35058.1 - 1.4e-40 139.4 36.9 2e-40 138.9 36.9 1.1 1 0 0 1 1 1 1 Amino acid permease DUF2104 PF09877.9 OAG35058.1 - 0.44 10.8 8.9 0.1 12.9 4.3 2.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2104) Arrestin_N PF00339.29 OAG35059.1 - 4.1e-12 46.4 0.0 1.4e-11 44.7 0.0 1.8 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 OAG35059.1 - 2.3e-08 34.5 0.1 7e-07 29.8 0.0 2.9 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain UAF_Rrn10 PF05234.11 OAG35060.1 - 0.00069 19.8 0.0 0.0011 19.2 0.0 1.3 1 0 0 1 1 1 1 UAF complex subunit Rrn10 Aldolase_II PF00596.21 OAG35063.1 - 4.9e-09 36.4 0.4 5.8e-09 36.1 0.4 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Iso_dh PF00180.20 OAG35064.1 - 7.7e-82 275.2 0.0 1e-81 274.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase MFS_1 PF07690.16 OAG35065.1 - 5.4e-18 65.0 34.5 5.4e-18 65.0 34.5 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily RhoGAP PF00620.27 OAG35066.1 - 1.9e-40 138.2 0.2 4.3e-40 137.0 0.2 1.6 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.29 OAG35066.1 - 4.7e-15 56.0 0.0 1.1e-14 54.8 0.0 1.7 1 0 0 1 1 1 1 PH domain PX PF00787.24 OAG35066.1 - 0.00014 21.9 0.2 0.00044 20.2 0.0 2.0 2 0 0 2 2 2 1 PX domain NARP1 PF12569.8 OAG35066.1 - 0.1 11.5 7.3 0.16 10.8 6.0 1.8 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 HCNGP PF07818.13 OAG35067.1 - 5.7e-29 100.6 0.0 9.4e-29 99.9 0.0 1.3 1 0 0 1 1 1 1 HCNGP-like protein Proteasome PF00227.26 OAG35068.1 - 1.4e-32 112.8 0.1 3.3e-32 111.5 0.1 1.6 2 0 0 2 2 2 1 Proteasome subunit KH_8 PF17903.1 OAG35069.1 - 2.2e-05 24.4 0.0 6.2e-05 23.0 0.0 1.7 2 0 0 2 2 2 1 Krr1 KH1 domain KH_1 PF00013.29 OAG35069.1 - 0.047 13.5 0.8 0.12 12.2 0.8 1.7 1 0 0 1 1 1 0 KH domain Kelch_5 PF13854.6 OAG35070.1 - 1.3e-09 37.8 5.7 1.4e-08 34.5 0.1 3.2 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.6 OAG35070.1 - 2.7e-09 37.1 7.9 0.0036 17.5 0.2 4.4 3 0 0 3 3 3 3 Galactose oxidase, central domain Kelch_2 PF07646.15 OAG35070.1 - 0.00033 20.5 4.7 15 5.8 0.0 5.1 5 0 0 5 5 5 3 Kelch motif Kelch_4 PF13418.6 OAG35070.1 - 0.013 15.5 7.6 2.1 8.4 0.0 4.8 5 1 0 5 5 5 0 Galactose oxidase, central domain Yip1 PF04893.17 OAG35070.1 - 0.12 12.0 1.5 0.54 9.9 0.0 2.1 2 0 0 2 2 2 0 Yip1 domain Alpha_GJ PF03229.13 OAG35070.1 - 0.23 12.0 2.8 0.47 11.0 2.8 1.5 1 0 0 1 1 1 0 Alphavirus glycoprotein J MDM31_MDM32 PF08118.11 OAG35071.1 - 4e-239 794.6 0.0 5e-239 794.3 0.0 1.0 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins Meth_synt_2 PF01717.18 OAG35072.1 - 9.8e-12 44.8 0.0 2.4e-10 40.2 0.0 2.5 2 1 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain APH PF01636.23 OAG35073.1 - 7.4e-11 42.4 0.0 1.1e-10 41.8 0.0 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 OAG35073.1 - 3.4e-05 23.6 0.5 5.4e-05 22.9 0.5 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 OAG35073.1 - 0.0012 18.5 0.1 0.0063 16.1 0.1 1.9 2 0 0 2 2 2 1 RIO1 family Pkinase PF00069.25 OAG35073.1 - 0.0024 17.3 0.1 0.01 15.2 0.1 1.8 2 0 0 2 2 2 1 Protein kinase domain DUF1679 PF07914.11 OAG35073.1 - 0.15 10.9 0.1 0.2 10.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) UL97 PF06734.12 OAG35073.1 - 0.15 11.9 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 UL97 EcKinase PF02958.20 OAG35073.1 - 0.21 10.9 1.7 0.42 9.9 0.7 1.9 2 0 0 2 2 2 0 Ecdysteroid kinase FMO-like PF00743.19 OAG35074.1 - 2.5e-13 49.3 0.1 1.4e-12 46.8 0.0 2.2 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OAG35074.1 - 1.2e-10 41.2 0.0 2.5e-10 40.1 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAG35074.1 - 1.5e-10 40.8 0.0 4e-08 32.8 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG35074.1 - 7.4e-07 28.6 0.0 7.1e-06 25.4 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 OAG35074.1 - 2.5e-05 24.4 0.1 0.0019 18.4 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 OAG35074.1 - 0.00065 20.2 0.4 0.14 12.7 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAG35074.1 - 0.003 17.6 0.2 8.7 6.3 0.1 4.6 4 1 1 5 5 5 1 FAD-NAD(P)-binding 2-Hacid_dh_C PF02826.19 OAG35074.1 - 0.072 12.4 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Zn_clus PF00172.18 OAG35075.1 - 0.00028 20.9 14.5 0.00068 19.7 14.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amidase PF01425.21 OAG35076.1 - 8.8e-33 113.9 1.2 1.8e-32 112.9 0.8 1.6 2 0 0 2 2 2 1 Amidase DUF4387 PF14330.6 OAG35077.1 - 2.4e-33 114.7 0.0 4.2e-33 113.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4387) AtuA PF07287.11 OAG35077.1 - 2.2e-08 33.3 0.0 0.0011 17.8 0.0 2.1 1 1 1 2 2 2 2 Acyclic terpene utilisation family protein AtuA Abhydrolase_6 PF12697.7 OAG35077.1 - 4.2e-08 34.1 3.1 4.8e-08 33.9 1.2 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family AXE1 PF05448.12 OAG35077.1 - 7e-08 31.5 0.0 4e-05 22.5 0.0 3.2 2 1 0 2 2 2 1 Acetyl xylan esterase (AXE1) Abhydrolase_1 PF00561.20 OAG35077.1 - 3.8e-07 30.0 0.1 6.4e-07 29.3 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAG35077.1 - 4.8e-07 29.3 0.0 1.1e-06 28.1 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 OAG35077.1 - 4.7e-05 23.0 0.0 0.0017 17.9 0.0 2.4 2 0 0 2 2 2 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 OAG35077.1 - 0.00048 19.8 0.0 0.00093 18.9 0.0 1.6 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.18 OAG35077.1 - 0.026 14.1 0.0 0.047 13.2 0.0 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family LIP PF03583.14 OAG35077.1 - 0.11 11.8 0.0 0.23 10.7 0.0 1.5 1 0 0 1 1 1 0 Secretory lipase DUF1373 PF07117.11 OAG35077.1 - 0.16 12.0 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1373) Pkinase PF00069.25 OAG35078.1 - 2.5e-28 99.2 0.1 1.2e-27 96.9 0.1 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG35078.1 - 2.1e-13 50.1 0.0 5.2e-13 48.9 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 OAG35078.1 - 0.00029 21.1 0.2 0.0017 18.6 0.0 2.3 2 1 0 2 2 2 1 FHA domain RBR PF17208.3 OAG35080.1 - 0.0011 19.6 1.5 0.0021 18.8 0.4 2.0 2 0 0 2 2 2 1 RNA binding Region BTB PF00651.31 OAG35080.1 - 0.0023 18.1 0.0 0.011 16.0 0.0 1.9 1 1 1 2 2 2 1 BTB/POZ domain M16C_assoc PF08367.11 OAG35081.1 - 4.5e-69 232.4 0.0 1.1e-68 231.1 0.0 1.7 2 0 0 2 2 2 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 OAG35081.1 - 5.8e-20 72.1 0.0 1.2e-13 51.5 0.0 3.2 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 OAG35081.1 - 2e-05 24.6 0.0 7.1e-05 22.8 0.0 2.0 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Taxilin PF09728.9 OAG35082.1 - 4.5e-82 275.7 58.4 4.5e-82 275.7 58.4 1.8 1 1 1 2 2 2 1 Myosin-like coiled-coil protein CENP-B_dimeris PF09026.10 OAG35082.1 - 2 8.9 14.0 1.2 9.5 9.3 2.7 2 1 0 2 2 2 0 Centromere protein B dimerisation domain DUF3543 PF12063.8 OAG35084.1 - 1.8e-93 312.6 0.1 3e-93 311.8 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase PF00069.25 OAG35084.1 - 2.9e-61 207.1 0.0 5.5e-61 206.2 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG35084.1 - 2.3e-43 148.4 0.0 4e-43 147.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OAG35084.1 - 0.1 12.5 0.1 0.25 11.2 0.1 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF4630 PF15443.6 OAG35084.1 - 0.13 12.4 1.2 0.28 11.4 1.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4630) Kinase-like PF14531.6 OAG35084.1 - 0.13 11.5 0.0 5.9 6.1 0.0 2.3 2 0 0 2 2 2 0 Kinase-like Antimicrobial_5 PF08026.11 OAG35084.1 - 0.39 10.8 2.1 1.1 9.4 2.1 1.7 1 0 0 1 1 1 0 Bee antimicrobial peptide ERAP1_C PF11838.8 OAG35085.1 - 5.9e-89 298.7 0.1 1.1e-88 297.8 0.1 1.5 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 OAG35085.1 - 3.5e-86 288.3 0.5 6.2e-86 287.5 0.5 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 OAG35085.1 - 2.4e-48 164.8 0.9 3.2e-48 164.4 0.2 1.6 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain p450 PF00067.22 OAG35086.1 - 2.2e-72 244.3 0.0 2.7e-72 244.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 OAG35087.1 - 6e-60 203.3 0.0 1e-59 202.5 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 adh_short_C2 PF13561.6 OAG35088.1 - 3.1e-53 180.7 0.1 3.6e-53 180.5 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG35088.1 - 6.2e-43 146.5 0.0 7.3e-43 146.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG35088.1 - 3.6e-11 43.3 1.3 8.3e-11 42.1 1.3 1.6 1 1 0 1 1 1 1 KR domain ThiF PF00899.21 OAG35088.1 - 0.0092 15.4 0.2 0.014 14.8 0.2 1.5 1 1 0 1 1 1 1 ThiF family TrmO_C PF18389.1 OAG35088.1 - 0.082 13.0 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 TrmO C-terminal domain Polysacc_synt_2 PF02719.15 OAG35088.1 - 0.095 11.8 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein adh_short_C2 PF13561.6 OAG35089.1 - 5.7e-36 124.2 0.0 7e-36 123.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG35089.1 - 1.9e-24 86.2 0.0 3.1e-24 85.5 0.0 1.3 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG35089.1 - 0.0059 16.5 0.1 0.012 15.5 0.1 1.5 1 0 0 1 1 1 1 KR domain FAD_binding_3 PF01494.19 OAG35090.1 - 1.2e-74 251.7 0.0 1.5e-74 251.4 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 OAG35090.1 - 0.017 14.4 0.0 0.06 12.6 0.0 1.9 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAG35090.1 - 0.13 11.3 0.0 5.9 5.9 0.0 2.5 3 0 0 3 3 3 0 FAD binding domain TRI12 PF06609.13 OAG35091.1 - 3.4e-114 382.5 23.0 4.1e-114 382.2 23.0 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG35091.1 - 5.1e-16 58.6 43.9 5.1e-16 58.6 43.9 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG35091.1 - 0.00013 20.9 5.9 0.00013 20.9 5.9 3.6 2 2 1 3 3 3 2 Sugar (and other) transporter PMI_typeI PF01238.21 OAG35093.1 - 3.1e-71 240.6 0.0 1.5e-70 238.3 0.0 1.8 1 1 0 1 1 1 1 Phosphomannose isomerase type I AraC_binding PF02311.19 OAG35093.1 - 0.00055 19.9 0.1 0.0041 17.0 0.0 2.3 3 0 0 3 3 3 1 AraC-like ligand binding domain Cupin_2 PF07883.11 OAG35093.1 - 0.027 14.2 0.2 1.7 8.4 0.3 2.3 2 0 0 2 2 2 0 Cupin domain C1_2 PF03107.16 OAG35094.1 - 0.011 16.0 3.3 0.029 14.7 3.3 1.7 1 0 0 1 1 1 0 C1 domain Ribosomal_L32p PF01783.23 OAG35094.1 - 0.029 14.6 2.7 0.17 12.2 0.2 3.3 3 0 0 3 3 3 0 Ribosomal L32p protein family zf-UBR PF02207.20 OAG35094.1 - 0.073 13.2 3.3 0.2 11.9 3.3 1.7 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) UPF0242 PF06785.11 OAG35094.1 - 0.14 12.2 15.9 0.29 11.2 1.0 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Siva PF05458.12 OAG35094.1 - 0.37 10.5 3.5 0.84 9.3 3.5 1.5 1 0 0 1 1 1 0 Cd27 binding protein (Siva) DUF1154 PF06631.11 OAG35094.1 - 4.3 7.4 11.3 21 5.3 11.3 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1154) CoA_binding_2 PF13380.6 OAG35095.1 - 3.2e-25 88.9 0.0 3.9e-25 88.6 0.0 1.1 1 0 0 1 1 1 1 CoA binding domain CoA_binding PF02629.19 OAG35095.1 - 0.1 13.3 0.0 0.16 12.6 0.0 1.2 1 0 0 1 1 1 0 CoA binding domain AA_permease_2 PF13520.6 OAG35096.1 - 3.8e-41 141.3 53.6 4.8e-41 141.0 53.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAG35096.1 - 1.2e-15 57.1 43.7 1.7e-15 56.6 43.7 1.1 1 0 0 1 1 1 1 Amino acid permease Transp_cyt_pur PF02133.15 OAG35097.1 - 9.7e-32 110.3 28.6 1.2e-31 109.9 28.6 1.2 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DIOX_N PF14226.6 OAG35098.1 - 2.7e-22 79.7 0.0 5.1e-22 78.9 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OAG35098.1 - 8e-18 64.8 0.0 1.2e-17 64.2 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily EF-hand_7 PF13499.6 OAG35099.1 - 9.9e-13 48.3 0.2 1.4e-07 31.8 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 OAG35099.1 - 9.2e-10 38.7 0.0 0.00053 20.3 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_6 PF13405.6 OAG35099.1 - 1.2e-09 37.4 0.1 0.0087 15.9 0.0 3.4 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 OAG35099.1 - 2e-09 36.3 0.0 0.027 14.0 0.0 3.6 3 1 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 OAG35099.1 - 6e-07 29.2 0.1 2.6e-05 24.0 0.1 2.8 3 0 0 3 3 3 1 EF-hand domain pair DUF3216 PF11505.8 OAG35099.1 - 0.065 13.4 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3216) Rad4 PF03835.15 OAG35101.1 - 1.8e-35 121.8 0.1 5.8e-35 120.1 0.1 1.9 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.9 OAG35101.1 - 1.1e-28 99.5 0.4 2e-28 98.6 0.4 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 OAG35101.1 - 2.4e-15 56.1 0.0 6.4e-15 54.7 0.0 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 OAG35101.1 - 7.1e-14 52.5 1.2 7.1e-14 52.5 1.2 3.6 3 0 0 3 3 3 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.19 OAG35101.1 - 0.002 18.6 0.0 0.0081 16.6 0.0 2.1 1 0 0 1 1 1 1 Transglutaminase-like superfamily Tyr-DNA_phospho PF06087.12 OAG35102.1 - 2.1e-135 451.9 0.0 2.5e-135 451.6 0.0 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase Glycos_transf_4 PF00953.21 OAG35102.1 - 5.2e-32 111.0 8.0 5.2e-32 111.0 8.0 2.4 3 0 0 3 3 3 1 Glycosyl transferase family 4 PLDc_2 PF13091.6 OAG35102.1 - 0.037 13.9 0.0 2.2 8.2 0.0 2.3 2 0 0 2 2 2 0 PLD-like domain WD40 PF00400.32 OAG35103.1 - 5.9e-09 36.4 7.2 0.02 15.8 0.3 5.2 4 1 0 4 4 4 3 WD domain, G-beta repeat NOA36 PF06524.12 OAG35103.1 - 0.012 14.9 8.9 0.02 14.2 8.9 1.3 1 0 0 1 1 1 0 NOA36 protein PPP4R2 PF09184.11 OAG35103.1 - 0.046 13.3 3.8 0.073 12.7 3.8 1.2 1 0 0 1 1 1 0 PPP4R2 WD40_3 PF15911.5 OAG35103.1 - 0.14 12.2 0.2 2.8 8.0 0.0 2.6 2 0 0 2 2 2 0 WD domain, G-beta repeat Ge1_WD40 PF16529.5 OAG35103.1 - 0.14 11.1 0.0 0.59 9.0 0.0 2.0 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein RXT2_N PF08595.11 OAG35103.1 - 1.3 9.1 5.4 2.9 7.9 5.4 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal Nucleo_P87 PF07267.11 OAG35103.1 - 3 6.6 4.9 4.7 6.0 4.9 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF908 PF06012.12 OAG35103.1 - 3.3 7.0 6.8 5.1 6.4 6.8 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) RRN3 PF05327.11 OAG35103.1 - 6.4 5.2 5.0 8.8 4.7 5.0 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF4611 PF15387.6 OAG35103.1 - 8.6 6.7 11.9 22 5.3 11.9 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) ACBP PF00887.19 OAG35104.1 - 3.9e-21 75.1 0.6 4.9e-21 74.7 0.6 1.1 1 0 0 1 1 1 1 Acyl CoA binding protein U-box PF04564.15 OAG35105.1 - 8.7e-24 83.5 0.3 1.2e-22 79.8 0.0 2.4 2 0 0 2 2 2 1 U-box domain TPR_2 PF07719.17 OAG35105.1 - 3.9e-10 39.0 6.4 0.017 15.2 0.4 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 OAG35105.1 - 3.7e-08 32.8 2.3 0.0027 17.5 0.2 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 OAG35105.1 - 1.1e-06 29.2 6.6 0.00077 20.1 0.3 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 OAG35105.1 - 9.7e-05 22.6 12.1 0.0055 17.0 3.2 2.7 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 OAG35105.1 - 0.00012 21.9 13.6 0.18 11.7 0.1 4.6 5 0 0 5 5 5 2 Tetratricopeptide repeat Lyase_aromatic PF00221.19 OAG35105.1 - 0.00057 18.7 1.1 0.00074 18.3 1.1 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase TPR_6 PF13174.6 OAG35105.1 - 0.0026 18.3 1.9 13 6.7 0.1 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 OAG35105.1 - 0.0044 17.5 4.4 0.75 10.4 0.2 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat CHIP_TPR_N PF18391.1 OAG35105.1 - 0.014 16.2 5.4 0.032 15.0 5.4 1.6 1 0 0 1 1 1 0 CHIP N-terminal tetratricopeptide repeat domain zf-NOSIP PF15906.5 OAG35105.1 - 0.038 14.1 0.0 0.089 12.9 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein TPR_14 PF13428.6 OAG35105.1 - 0.042 14.7 10.5 1.7 9.7 0.1 4.1 3 2 1 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 OAG35105.1 - 0.064 13.3 8.2 0.12 12.4 0.1 4.0 4 1 0 4 4 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 OAG35105.1 - 0.12 12.1 2.2 0.26 11.0 0.1 2.5 2 0 0 2 2 2 0 TPR repeat ANAPC3 PF12895.7 OAG35105.1 - 0.16 12.2 6.5 1.7 8.9 1.5 2.7 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 FA_desaturase PF00487.24 OAG35106.1 - 2e-20 73.7 13.6 2e-20 73.7 13.6 1.8 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.28 OAG35106.1 - 1.4e-16 60.3 0.1 3.7e-16 59.0 0.1 1.7 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_9 PF13454.6 OAG35108.1 - 0.0013 18.7 0.0 0.0024 17.9 0.0 1.4 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 OAG35108.1 - 0.0014 17.9 0.0 0.0027 17.0 0.0 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG35108.1 - 0.026 13.7 0.0 0.067 12.3 0.0 1.6 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) zf-RING_2 PF13639.6 OAG35109.1 - 1.2e-13 51.1 4.6 2e-13 50.4 4.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 OAG35109.1 - 5.1e-12 45.3 2.1 9e-12 44.5 2.1 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 OAG35109.1 - 1.6e-08 34.2 4.6 2.7e-08 33.5 4.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OAG35109.1 - 9.6e-08 32.2 3.7 2.5e-07 30.9 3.7 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 OAG35109.1 - 1.9e-07 30.8 4.1 3.2e-07 30.1 4.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OAG35109.1 - 1.4e-05 24.9 4.7 2.5e-05 24.0 4.7 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 OAG35109.1 - 1.6e-05 24.8 2.5 2.6e-05 24.1 2.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 OAG35109.1 - 0.00057 19.9 4.3 0.0011 19.0 4.3 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 OAG35109.1 - 0.0016 18.4 0.8 0.0034 17.4 0.8 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 OAG35109.1 - 0.0022 17.8 1.5 0.0039 17.0 1.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 OAG35109.1 - 0.028 14.2 3.5 0.048 13.5 3.5 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.29 OAG35109.1 - 0.083 12.8 2.8 0.15 12.0 2.8 1.4 1 0 0 1 1 1 0 PHD-finger Zn_ribbon_17 PF17120.5 OAG35109.1 - 0.16 11.6 1.6 0.3 10.7 1.6 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING-like PF08746.11 OAG35109.1 - 0.17 12.2 2.2 0.3 11.4 2.2 1.4 1 0 0 1 1 1 0 RING-like domain FANCL_C PF11793.8 OAG35109.1 - 0.5 10.6 3.8 2.6 8.3 3.8 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain DUF1180 PF06679.12 OAG35109.1 - 4.6 7.6 6.2 3 8.2 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1180) TB2_DP1_HVA22 PF03134.19 OAG35110.1 - 3.3e-22 78.2 7.2 5e-22 77.6 7.2 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family TANGO2 PF05742.12 OAG35111.1 - 9.1e-71 238.9 0.0 1.1e-70 238.6 0.0 1.0 1 0 0 1 1 1 1 Transport and Golgi organisation 2 PGDH_C PF16896.5 OAG35111.1 - 0.032 14.2 0.0 0.048 13.6 0.0 1.3 1 0 0 1 1 1 0 Phosphogluconate dehydrogenase (decarboxylating) C-term Fungal_trans_2 PF11951.8 OAG35112.1 - 4.3e-10 39.0 1.0 7.1e-10 38.3 0.6 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain PEP_mutase PF13714.6 OAG35113.1 - 4.4e-58 196.6 1.2 5e-58 196.4 1.2 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Peptidase_M13_N PF05649.13 OAG35114.1 - 1.4e-94 317.9 0.0 2.1e-94 317.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 OAG35114.1 - 1.8e-62 210.6 0.1 2.9e-62 209.9 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M13 DUF1289 PF06945.13 OAG35114.1 - 0.029 14.2 0.0 0.077 12.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1289) PSII_Pbs27 PF13326.6 OAG35114.1 - 0.29 11.4 1.3 4.6 7.6 0.0 2.8 2 1 1 3 3 3 0 Photosystem II Pbs27 SET PF00856.28 OAG35115.1 - 0.14 12.5 0.0 4.6 7.6 0.0 2.6 1 1 0 1 1 1 0 SET domain p450 PF00067.22 OAG35116.1 - 6.2e-27 94.4 0.0 9.8e-27 93.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 ORC6 PF05460.13 OAG35117.1 - 0.041 13.2 5.5 0.063 12.5 5.5 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Response_reg PF00072.24 OAG35118.1 - 1.6e-26 92.6 0.3 5.8e-26 90.9 0.3 2.0 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 OAG35118.1 - 4.4e-26 91.6 0.0 7.1e-25 87.7 0.0 2.5 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS PF00989.25 OAG35118.1 - 2.1e-17 63.1 0.0 2.3e-10 40.5 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.10 OAG35118.1 - 2.6e-17 63.1 0.0 1.2e-07 32.0 0.0 2.4 2 0 0 2 2 2 2 PAS fold HisKA PF00512.25 OAG35118.1 - 1e-16 60.7 0.1 3.1e-16 59.2 0.1 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.7 OAG35118.1 - 1.2e-12 48.0 0.0 7.7e-11 42.2 0.0 2.8 2 1 0 2 2 2 1 PAS domain PAS_7 PF12860.7 OAG35118.1 - 0.12 12.5 0.0 0.47 10.6 0.0 2.0 2 0 0 2 2 2 0 PAS fold DUF4551 PF15087.6 OAG35119.1 - 1.7 7.4 3.0 2.1 7.1 3.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Acetyltransf_1 PF00583.25 OAG35120.1 - 1.4e-12 47.8 0.0 7.3e-12 45.6 0.0 2.1 2 1 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OAG35120.1 - 4.6e-11 42.7 0.0 7.6e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OAG35120.1 - 2.7e-07 30.9 0.0 4.5e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 OAG35120.1 - 0.00024 21.2 0.0 0.0056 16.7 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAG35120.1 - 0.0045 16.9 0.0 0.0089 16.0 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein SCHIP-1 PF10148.9 OAG35120.1 - 0.2 11.3 1.9 0.29 10.7 1.9 1.3 1 0 0 1 1 1 0 Schwannomin-interacting protein 1 DUF5423 PF17461.2 OAG35120.1 - 0.3 9.9 3.2 0.55 9.0 2.8 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5423) SDA1 PF05285.12 OAG35120.1 - 0.94 8.8 6.3 1.3 8.4 6.3 1.2 1 0 0 1 1 1 0 SDA1 Asp_protease PF09668.10 OAG35121.1 - 3e-58 195.0 0.1 4.4e-58 194.5 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 OAG35121.1 - 2e-22 79.6 0.1 3.8e-22 78.7 0.1 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 OAG35121.1 - 2.1e-11 44.3 0.1 4.2e-11 43.3 0.1 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 OAG35121.1 - 5.2e-05 23.0 0.0 0.00012 21.8 0.0 1.6 1 1 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.20 OAG35121.1 - 5.3e-05 23.5 0.0 0.0001 22.6 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease DUF1068 PF06364.12 OAG35121.1 - 0.033 14.1 1.0 0.056 13.3 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1068) ubiquitin PF00240.23 OAG35121.1 - 0.07 12.9 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin family AMP-binding PF00501.28 OAG35123.1 - 5.4e-76 255.9 0.0 3.8e-74 249.8 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.20 OAG35123.1 - 2.1e-55 188.2 0.0 7.1e-32 110.7 0.0 2.8 2 1 0 2 2 2 2 Condensation domain PP-binding PF00550.25 OAG35123.1 - 7.8e-27 93.4 0.4 7.3e-12 45.5 0.0 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site Acetyltransf_8 PF13523.6 OAG35124.1 - 5e-43 146.3 1.4 7.4e-43 145.7 1.4 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Gly_transf_sug PF04488.15 OAG35126.1 - 3.1e-14 53.4 0.0 7.2e-14 52.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif CFEM PF05730.11 OAG35127.1 - 4.3e-11 42.7 1.7 1.1e-10 41.5 1.7 1.7 1 0 0 1 1 1 1 CFEM domain Podoplanin PF05808.11 OAG35127.1 - 0.28 11.3 12.6 0.38 10.9 12.6 1.1 1 0 0 1 1 1 0 Podoplanin RIFIN PF02009.16 OAG35127.1 - 1 9.2 2.6 1.2 9.0 2.6 1.3 1 0 0 1 1 1 0 Rifin Hamartin PF04388.12 OAG35127.1 - 4.4 5.8 6.9 5.2 5.6 6.9 1.0 1 0 0 1 1 1 0 Hamartin protein Acetyltransf_1 PF00583.25 OAG35128.1 - 0.00015 22.0 0.0 0.00025 21.3 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OAG35128.1 - 0.0034 17.3 0.0 0.0064 16.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OAG35128.1 - 0.018 15.4 0.0 0.044 14.2 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain GLTP PF08718.11 OAG35129.1 - 2.7e-37 128.3 0.0 1.1e-36 126.4 0.0 1.7 2 0 0 2 2 2 1 Glycolipid transfer protein (GLTP) Acyl_transf_3 PF01757.22 OAG35130.1 - 5e-34 117.9 37.0 6.4e-34 117.5 37.0 1.1 1 0 0 1 1 1 1 Acyltransferase family CholecysA-Rec_N PF09193.10 OAG35131.1 - 0.11 12.5 0.2 0.22 11.5 0.2 1.4 1 0 0 1 1 1 0 Cholecystokinin A receptor, N-terminal MFS_1 PF07690.16 OAG35132.1 - 9.8e-14 51.0 54.5 9.8e-14 51.0 54.5 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 OAG35132.1 - 5.9e-12 44.8 27.1 8.2e-12 44.3 27.1 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2107 PF09880.9 OAG35132.1 - 0.096 12.8 2.5 2 8.6 0.0 3.8 3 1 1 4 4 4 0 Predicted membrane protein (DUF2107) ABC_membrane PF00664.23 OAG35133.1 - 9.8e-79 264.8 37.0 1.9e-43 149.1 7.6 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 OAG35133.1 - 2.1e-65 219.4 0.0 3e-31 108.8 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 OAG35133.1 - 1.1e-14 54.4 0.8 2.5e-05 23.8 0.0 4.2 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 OAG35133.1 - 2.2e-09 36.9 0.1 0.0011 18.7 0.0 3.0 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 OAG35133.1 - 4.5e-09 36.7 1.2 0.0093 16.2 0.1 4.1 2 2 0 2 2 2 2 AAA domain ABC_ATPase PF09818.9 OAG35133.1 - 6.2e-09 35.2 0.0 0.0009 18.2 0.0 3.0 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_16 PF13191.6 OAG35133.1 - 8.9e-09 36.0 0.2 0.0091 16.4 0.1 2.9 2 1 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 OAG35133.1 - 3.2e-08 33.6 0.0 0.00056 19.9 0.0 2.9 3 0 0 3 3 3 2 RsgA GTPase AAA_23 PF13476.6 OAG35133.1 - 2.3e-06 28.3 0.0 0.078 13.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 OAG35133.1 - 3.4e-06 26.9 0.4 0.14 11.9 0.0 3.5 2 2 0 2 2 2 2 AAA domain AAA_25 PF13481.6 OAG35133.1 - 1.4e-05 24.7 0.6 0.12 11.9 0.0 4.1 4 0 0 4 4 4 1 AAA domain AAA_18 PF13238.6 OAG35133.1 - 3.4e-05 24.4 0.1 0.4 11.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.6 OAG35133.1 - 8.9e-05 22.4 5.3 0.68 9.7 0.0 4.1 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF3987 PF13148.6 OAG35133.1 - 0.00015 20.9 0.0 0.014 14.4 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3987) MMR_HSR1 PF01926.23 OAG35133.1 - 0.00037 20.5 0.1 0.24 11.5 0.0 3.0 3 0 0 3 3 2 1 50S ribosome-binding GTPase AAA_5 PF07728.14 OAG35133.1 - 0.00054 20.0 0.0 1.4 8.9 0.0 3.5 4 0 0 4 4 3 1 AAA domain (dynein-related subfamily) AAA PF00004.29 OAG35133.1 - 0.00057 20.3 0.1 3.3 8.1 0.0 4.0 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 OAG35133.1 - 0.0014 18.0 0.0 0.23 10.7 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_33 PF13671.6 OAG35133.1 - 0.0023 18.1 0.1 1.8 8.7 0.0 2.9 3 0 0 3 3 2 1 AAA domain PRK PF00485.18 OAG35133.1 - 0.0024 17.7 0.0 1.1 9.0 0.0 2.6 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_15 PF13175.6 OAG35133.1 - 0.0024 17.6 0.0 0.8 9.3 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain DUF87 PF01935.17 OAG35133.1 - 0.0035 17.5 1.7 0.26 11.4 0.0 3.2 3 0 0 3 3 3 1 Helicase HerA, central domain Rad17 PF03215.15 OAG35133.1 - 0.0045 16.9 0.0 2.4 8.0 0.0 2.9 3 0 0 3 3 3 1 Rad17 P-loop domain Cytidylate_kin PF02224.18 OAG35133.1 - 0.005 16.6 0.2 0.72 9.5 0.1 2.7 2 0 0 2 2 2 1 Cytidylate kinase SbcCD_C PF13558.6 OAG35133.1 - 0.0056 16.9 1.4 2.1 8.7 0.2 3.6 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_24 PF13479.6 OAG35133.1 - 0.007 16.1 0.0 2.2 8.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain G-alpha PF00503.20 OAG35133.1 - 0.0081 15.4 0.0 3.5 6.7 0.0 2.3 2 0 0 2 2 2 1 G-protein alpha subunit APS_kinase PF01583.20 OAG35133.1 - 0.012 15.5 0.0 5.3 6.9 0.0 2.4 2 0 0 2 2 2 0 Adenylylsulphate kinase RNA_helicase PF00910.22 OAG35133.1 - 0.012 16.0 0.0 9.2 6.7 0.0 2.6 2 0 0 2 2 2 0 RNA helicase Tex_YqgF PF16921.5 OAG35133.1 - 0.015 15.8 0.1 0.038 14.4 0.1 1.7 1 0 0 1 1 1 0 Tex protein YqgF-like domain Mg_chelatase PF01078.21 OAG35133.1 - 0.017 14.5 0.0 5.1 6.4 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 OAG35133.1 - 0.019 14.5 0.0 6.7 6.2 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_28 PF13521.6 OAG35133.1 - 0.02 15.1 0.1 9.1 6.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain Ploopntkinase3 PF18751.1 OAG35133.1 - 0.05 13.5 0.0 4.3 7.2 0.0 2.5 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 DEAD PF00270.29 OAG35133.1 - 0.055 13.2 0.1 2.6 7.8 0.0 3.2 3 1 0 3 3 3 0 DEAD/DEAH box helicase ATP_bind_1 PF03029.17 OAG35133.1 - 0.061 13.1 0.5 14 5.4 0.0 2.9 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein TniB PF05621.11 OAG35133.1 - 0.067 12.6 0.1 23 4.3 0.0 3.7 4 0 0 4 4 4 0 Bacterial TniB protein SRP54 PF00448.22 OAG35133.1 - 0.073 12.7 0.0 8.9 5.9 0.0 2.9 3 0 0 3 3 2 0 SRP54-type protein, GTPase domain NB-ARC PF00931.22 OAG35133.1 - 0.098 11.8 0.0 11 5.1 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain IstB_IS21 PF01695.17 OAG35133.1 - 0.11 12.2 1.0 19 4.9 0.0 3.8 4 0 0 4 4 4 0 IstB-like ATP binding protein AAA_17 PF13207.6 OAG35133.1 - 0.13 12.7 0.1 20 5.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain Glyoxalase PF00903.25 OAG35134.1 - 4.1e-12 46.4 0.0 7e-12 45.7 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 OAG35134.1 - 1.7e-09 37.9 0.0 2.2e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 OAG35134.1 - 3.8e-07 30.9 0.0 1.7e-06 28.8 0.0 1.9 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_3 PF13468.6 OAG35134.1 - 0.0024 18.0 0.0 0.013 15.6 0.0 1.9 1 1 0 1 1 1 1 Glyoxalase-like domain AtuA PF07287.11 OAG35135.1 - 2.8e-61 207.2 0.6 1.1e-28 100.0 0.1 3.0 2 1 0 2 2 2 2 Acyclic terpene utilisation family protein AtuA DUF4413 PF14372.6 OAG35139.1 - 0.15 12.4 0.0 0.39 11.1 0.0 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4413) FAD_binding_3 PF01494.19 OAG35140.1 - 2e-29 103.0 0.0 5.6e-29 101.5 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAG35140.1 - 2e-06 27.6 1.3 0.00078 19.1 0.5 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAG35140.1 - 5.7e-06 26.5 0.2 1.6e-05 25.0 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAG35140.1 - 2.7e-05 23.5 0.7 0.00062 19.1 0.2 2.2 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAG35140.1 - 5.8e-05 22.3 0.2 9.6e-05 21.6 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 OAG35140.1 - 0.0002 21.8 0.2 0.011 16.3 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 OAG35140.1 - 0.003 16.7 0.0 0.37 9.8 0.0 2.2 2 0 0 2 2 2 2 Squalene epoxidase Lycopene_cycl PF05834.12 OAG35140.1 - 0.0063 15.6 0.9 0.015 14.3 0.7 1.9 2 1 0 2 2 2 1 Lycopene cyclase protein HI0933_like PF03486.14 OAG35140.1 - 0.0082 14.9 0.1 0.03 13.0 0.0 1.8 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 OAG35140.1 - 0.019 14.2 0.1 0.029 13.6 0.1 1.3 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.22 OAG35140.1 - 0.067 12.3 0.2 0.1 11.7 0.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 OAG35140.1 - 0.11 11.8 0.3 0.22 10.7 0.3 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 OAG35140.1 - 0.14 12.1 0.1 0.22 11.4 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_25 PF13649.6 OAG35141.1 - 1e-10 42.1 1.4 1.1e-09 38.9 0.0 3.1 3 0 0 3 3 3 1 Methyltransferase domain PrmA PF06325.13 OAG35141.1 - 1.4e-09 37.8 0.1 3.4e-09 36.5 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 OAG35141.1 - 1.8e-08 34.9 0.1 2.1e-07 31.5 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG35141.1 - 1.2e-06 28.4 0.0 5.7e-06 26.2 0.0 2.0 1 1 1 2 2 2 1 Methyltransferase domain MTS PF05175.14 OAG35141.1 - 8.8e-06 25.4 0.1 1.9e-05 24.3 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.7 OAG35141.1 - 2e-05 24.6 0.0 6e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAG35141.1 - 3.4e-05 23.7 0.0 0.00015 21.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 OAG35141.1 - 0.00012 21.1 0.1 0.00027 20.0 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1698) RasGAP_C PF03836.15 OAG35141.1 - 0.00046 20.3 0.6 0.0011 19.1 0.6 1.6 1 0 0 1 1 1 1 RasGAP C-terminus Methyltransf_12 PF08242.12 OAG35141.1 - 0.0016 19.1 0.3 0.0099 16.6 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 OAG35141.1 - 0.003 17.3 0.0 0.005 16.6 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.9 OAG35141.1 - 0.016 15.0 0.0 0.03 14.1 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_2 PF00891.18 OAG35141.1 - 0.057 12.7 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase domain CMAS PF02353.20 OAG35141.1 - 0.077 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 OAG35142.1 - 0.00015 22.4 0.0 0.00046 20.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG35142.1 - 0.0024 18.5 0.0 0.0084 16.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG35142.1 - 0.02 14.7 0.0 0.03 14.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 OAG35142.1 - 0.059 14.1 0.0 0.11 13.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Citrate_bind PF16114.5 OAG35142.1 - 0.18 11.3 0.0 19 4.7 0.0 2.2 2 0 0 2 2 2 0 ATP citrate lyase citrate-binding p450 PF00067.22 OAG35144.1 - 1.8e-59 201.8 0.0 8.5e-59 199.5 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 Fungal_trans_2 PF11951.8 OAG35145.1 - 0.0037 16.1 0.4 0.27 10.0 0.1 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Enkurin PF13864.6 OAG35146.1 - 0.083 13.3 3.3 0.25 11.8 3.3 1.8 1 0 0 1 1 1 0 Calmodulin-binding AA_permease_2 PF13520.6 OAG35147.1 - 7.6e-47 160.1 58.6 9.3e-47 159.8 58.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAG35147.1 - 7.6e-31 107.2 50.5 1e-30 106.8 50.5 1.1 1 0 0 1 1 1 1 Amino acid permease DUF4227 PF14004.6 OAG35147.1 - 0.2 11.7 4.3 2.2 8.3 2.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4227) DUF4083 PF13314.6 OAG35147.1 - 0.27 11.2 0.1 0.27 11.2 0.1 3.8 5 0 0 5 5 5 0 Domain of unknown function (DUF4083) DUF1356 PF07092.12 OAG35147.1 - 0.3 10.3 1.5 0.96 8.7 1.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1356) TauD PF02668.16 OAG35148.1 - 6.7e-39 134.3 0.0 9.6e-39 133.8 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 OAG35148.1 - 1.3e-13 51.4 0.1 1.1e-11 45.2 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF971) CsiD PF08943.10 OAG35148.1 - 0.3 10.1 0.0 0.56 9.3 0.0 1.3 1 0 0 1 1 1 0 CsiD TMF_TATA_bd PF12325.8 OAG35149.1 - 0.011 15.9 1.1 0.037 14.3 0.0 2.1 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Fib_alpha PF08702.10 OAG35149.1 - 0.46 10.7 4.6 0.44 10.7 1.4 2.1 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Actin PF00022.19 OAG35150.1 - 6.4e-13 48.1 0.0 5.3e-08 31.9 0.0 3.3 3 1 0 3 3 3 3 Actin XPG_I PF00867.18 OAG35151.1 - 4.9e-25 87.7 0.0 9.8e-25 86.7 0.0 1.5 1 0 0 1 1 1 1 XPG I-region GEN1_C PF18380.1 OAG35151.1 - 8.7e-24 84.4 0.1 2.5e-23 83.0 0.1 1.7 1 0 0 1 1 1 1 Holliday junction resolvase Gen1 C-terminal domain XPG_N PF00752.17 OAG35151.1 - 2.1e-05 24.9 0.0 4.6e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.7 OAG35151.1 - 0.0059 16.1 0.0 0.014 14.9 0.0 1.6 1 0 0 1 1 1 1 XPG domain containing PAN_4 PF14295.6 OAG35151.1 - 0.22 11.5 0.8 5.6 7.0 0.0 2.5 2 0 0 2 2 2 0 PAN domain FolB PF02152.18 OAG35152.1 - 3.9e-29 101.4 0.1 2.4e-18 66.7 0.8 2.1 2 0 0 2 2 2 2 Dihydroneopterin aldolase Htr2 PF17909.1 OAG35152.1 - 0.28 11.5 3.3 1.3 9.4 0.0 3.1 3 0 0 3 3 3 0 Htr2 transmembrane domain Pkinase PF00069.25 OAG35153.1 - 3.1e-62 210.3 0.0 4.2e-62 209.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG35153.1 - 4.8e-28 98.2 0.0 6.9e-28 97.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 OAG35153.1 - 0.0064 17.2 0.8 0.024 15.3 0.1 2.4 2 0 0 2 2 2 1 Protein kinase C terminal domain Pkinase_fungal PF17667.1 OAG35153.1 - 0.082 11.7 0.0 0.17 10.6 0.0 1.6 1 1 0 1 1 1 0 Fungal protein kinase F-box-like PF12937.7 OAG35154.1 - 0.005 16.7 0.0 0.018 14.9 0.0 2.0 1 0 0 1 1 1 1 F-box-like SOBP PF15279.6 OAG35155.1 - 0.014 16.1 0.6 0.018 15.7 0.6 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein BUD22 PF09073.10 OAG35156.1 - 0.028 13.8 0.1 0.034 13.5 0.1 1.0 1 0 0 1 1 1 0 BUD22 DUF2722 PF10846.8 OAG35156.1 - 1.2 8.0 2.0 1.5 7.7 2.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) SDA1 PF05285.12 OAG35157.1 - 7.3 5.9 10.1 9.3 5.6 10.1 1.1 1 0 0 1 1 1 0 SDA1 PAN_1 PF00024.26 OAG35158.1 - 9.6e-05 22.3 2.0 0.0022 17.9 0.0 2.9 3 0 0 3 3 3 1 PAN domain Glyco_hydro_16 PF00722.21 OAG35158.1 - 0.00074 19.0 0.6 0.0014 18.1 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 MFS_1 PF07690.16 OAG35159.1 - 1.1e-28 100.3 39.2 5.9e-26 91.2 32.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 OAG35159.1 - 0.11 11.8 24.6 0.18 11.1 21.1 2.4 2 1 0 2 2 2 0 Uncharacterised MFS-type transporter YbfB IL10 PF00726.17 OAG35159.1 - 0.2 11.1 0.0 0.43 10.1 0.0 1.5 1 0 0 1 1 1 0 Interleukin 10 HMG_box PF00505.19 OAG35160.1 - 2e-24 85.8 1.9 2e-24 85.8 1.9 1.8 2 1 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 OAG35160.1 - 2.9e-18 66.2 2.5 5.6e-18 65.3 2.5 1.5 1 0 0 1 1 1 1 HMG-box domain Ccdc124 PF06244.12 OAG35160.1 - 0.0037 17.8 0.5 0.0037 17.8 0.5 2.4 1 1 1 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 HMG_box_5 PF14887.6 OAG35160.1 - 0.016 15.1 0.7 0.016 15.1 0.7 1.7 2 0 0 2 2 2 0 HMG (high mobility group) box 5 CHDNT PF08073.12 OAG35160.1 - 0.024 14.6 0.0 0.056 13.4 0.0 1.6 1 0 0 1 1 1 0 CHDNT (NUC034) domain YABBY PF04690.13 OAG35160.1 - 0.14 12.7 3.7 0.1 13.1 2.6 1.4 1 1 0 1 1 1 0 YABBY protein DUF959 PF06121.14 OAG35160.1 - 0.15 12.3 2.4 0.081 13.2 0.5 1.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF959) ATG11 PF10377.9 OAG35161.1 - 2.7e-46 156.8 0.0 2.7e-46 156.8 0.0 4.3 5 0 0 5 5 5 1 Autophagy-related protein 11 APG17 PF04108.12 OAG35161.1 - 4.8e-05 22.7 13.1 9.9e-05 21.6 4.6 6.6 3 2 2 5 5 5 2 Autophagy protein Apg17 Tropomyosin PF00261.20 OAG35161.1 - 0.002 17.5 33.3 0.002 17.5 33.3 5.9 5 1 1 6 6 6 1 Tropomyosin Fez1 PF06818.15 OAG35161.1 - 0.0022 18.5 19.4 0.0022 18.5 19.4 5.9 3 2 2 5 5 5 1 Fez1 TPR_MLP1_2 PF07926.12 OAG35161.1 - 0.0024 17.9 14.2 0.0024 17.9 14.2 9.5 7 3 4 11 11 11 1 TPR/MLP1/MLP2-like protein DUF1319 PF07028.11 OAG35161.1 - 0.13 12.5 0.1 0.13 12.5 0.1 6.3 7 0 0 7 7 7 0 Protein of unknown function (DUF1319) Surfac_D-trimer PF09006.11 OAG35161.1 - 1.2 9.0 4.2 1.1 9.2 0.2 3.1 3 0 0 3 3 3 0 Lung surfactant protein D coiled-coil trimerisation Spc7 PF08317.11 OAG35161.1 - 8.2 5.2 93.3 0.17 10.7 20.4 6.8 5 2 2 7 7 7 0 Spc7 kinetochore protein Sas6_CC PF18594.1 OAG35161.1 - 9.3 6.1 8.5 5 7.0 0.2 4.0 3 0 0 3 3 3 0 Sas6/XLF/XRCC4 coiled-coil domain DUF3445 PF11927.8 OAG35162.1 - 3.8e-76 255.7 0.0 4.6e-76 255.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Homoserine_dh PF00742.19 OAG35163.1 - 1.1e-52 178.5 0.0 1.4e-52 178.1 0.0 1.1 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 OAG35163.1 - 1.7e-14 54.5 0.0 3.3e-14 53.5 0.0 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DUF1180 PF06679.12 OAG35165.1 - 0.0037 17.7 0.8 0.007 16.8 0.8 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1180) EphA2_TM PF14575.6 OAG35165.1 - 0.014 16.2 0.0 0.02 15.7 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Herpes_gE PF02480.16 OAG35165.1 - 0.015 14.1 0.0 0.018 13.9 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E CD34_antigen PF06365.12 OAG35165.1 - 0.031 13.8 0.0 0.043 13.4 0.0 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family DUF4448 PF14610.6 OAG35165.1 - 0.033 14.0 0.0 0.041 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Peptidase_M56 PF05569.11 OAG35165.1 - 0.035 13.3 0.0 0.047 12.9 0.0 1.1 1 0 0 1 1 1 0 BlaR1 peptidase M56 TMEM154 PF15102.6 OAG35165.1 - 0.039 13.9 0.0 0.055 13.4 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family stn_TNFRSF12A PF12191.8 OAG35165.1 - 0.097 12.9 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain AJAP1_PANP_C PF15298.6 OAG35165.1 - 0.14 12.3 0.2 0.18 12.0 0.2 1.2 1 0 0 1 1 1 0 AJAP1/PANP C-terminus PepSY_TM PF03929.16 OAG35165.1 - 0.16 11.6 0.7 0.26 10.9 0.5 1.3 1 1 0 1 1 1 0 PepSY-associated TM region BTB PF00651.31 OAG35166.1 - 0.02 15.1 0.0 0.06 13.6 0.0 1.8 1 0 0 1 1 1 0 BTB/POZ domain DUF4215 PF13948.6 OAG35167.1 - 0.00092 19.6 5.2 0.00092 19.6 5.2 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF4215) MAD PF05557.13 OAG35169.1 - 9.4e-67 225.8 67.0 1.9e-66 224.8 66.9 1.5 1 1 0 1 1 1 1 Mitotic checkpoint protein CLZ PF16526.5 OAG35169.1 - 0.0044 17.3 4.0 0.0044 17.3 4.0 6.8 5 3 2 7 7 7 3 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Fungal_trans_2 PF11951.8 OAG35170.1 - 0.04 12.7 0.0 0.091 11.6 0.0 1.5 1 0 0 1 1 1 0 Fungal specific transcription factor domain adh_short PF00106.25 OAG35171.1 - 2.2e-37 128.4 0.0 3.1e-37 127.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG35171.1 - 2.4e-34 118.9 0.0 4.1e-34 118.2 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG35171.1 - 2.6e-09 37.3 0.0 4e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG35171.1 - 0.013 15.0 0.0 0.26 10.7 0.0 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family LDcluster4 PF18306.1 OAG35171.1 - 0.086 12.4 0.4 0.2 11.2 0.3 1.6 2 0 0 2 2 2 0 SLOG cluster4 family MCR_C PF04609.12 OAG35171.1 - 0.13 11.3 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 Methyl-coenzyme M reductase operon protein C Zn_clus PF00172.18 OAG35172.1 - 7.5e-10 38.8 15.9 2.4e-09 37.1 9.9 2.4 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Ank_2 PF12796.7 OAG35173.1 - 5.8e-86 283.2 0.7 6.5e-13 49.1 0.0 7.3 4 1 4 8 8 7 6 Ankyrin repeats (3 copies) Ank PF00023.30 OAG35173.1 - 2.6e-72 236.3 0.0 3.6e-06 27.2 0.0 12.7 11 1 1 12 12 12 12 Ankyrin repeat Ank_3 PF13606.6 OAG35173.1 - 2.1e-65 208.9 0.9 5.9e-05 23.2 0.0 13.8 14 0 0 14 14 13 11 Ankyrin repeat Ank_4 PF13637.6 OAG35173.1 - 2.7e-58 193.6 0.1 2.1e-09 37.7 0.0 8.1 5 1 2 7 7 7 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 OAG35173.1 - 2.3e-47 158.4 0.1 4.1e-07 30.2 0.0 9.4 3 1 8 11 11 10 10 Ankyrin repeats (many copies) HET PF06985.11 OAG35173.1 - 3.2e-10 40.5 8.5 2.2e-08 34.5 2.0 2.7 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) NACHT PF05729.12 OAG35173.1 - 5.3e-08 32.9 0.1 2.4e-07 30.8 0.1 2.1 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 OAG35173.1 - 1.5e-05 25.5 0.4 0.00015 22.2 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain Ribosomal_S6 PF01250.17 OAG35173.1 - 3.8e-05 23.9 0.1 5.2 7.4 0.0 4.7 4 1 0 4 4 4 1 Ribosomal protein S6 AAA_22 PF13401.6 OAG35173.1 - 0.0002 21.6 0.0 0.0045 17.2 0.0 2.8 2 1 1 3 3 3 1 AAA domain PEGA PF08308.11 OAG35173.1 - 0.00041 20.2 0.1 6.3 6.8 0.0 5.3 5 1 1 6 6 6 1 PEGA domain VWA_3_C PF18571.1 OAG35173.1 - 0.00099 18.9 20.4 1.1 9.2 0.4 8.2 8 0 0 8 8 8 1 von Willebrand factor type A C-terminal domain ABC_tran PF00005.27 OAG35173.1 - 0.089 13.3 0.0 0.2 12.1 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_18 PF13238.6 OAG35173.1 - 0.12 12.9 0.0 0.82 10.2 0.0 2.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 OAG35173.1 - 0.13 12.0 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ploopntkinase3 PF18751.1 OAG35173.1 - 0.15 11.9 0.1 1.6 8.6 0.0 2.6 3 0 0 3 3 3 0 P-loop Nucleotide Kinase3 BATS PF06968.13 OAG35173.1 - 0.16 12.2 0.0 0.6 10.3 0.0 2.0 1 0 0 1 1 1 0 Biotin and Thiamin Synthesis associated domain AAA_30 PF13604.6 OAG35173.1 - 0.16 11.7 0.0 0.52 10.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.14 OAG35173.1 - 0.38 9.9 2.7 0.46 9.7 0.5 1.9 1 1 1 2 2 2 0 KAP family P-loop domain NmrA PF05368.13 OAG35174.1 - 5e-60 203.0 0.0 6.7e-60 202.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG35174.1 - 7.6e-18 65.1 0.0 1.2e-17 64.4 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 OAG35174.1 - 2e-07 30.3 0.1 8.6e-07 28.2 0.0 1.8 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Sacchrp_dh_NADP PF03435.18 OAG35174.1 - 0.0055 17.0 0.1 0.0077 16.5 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 OAG35174.1 - 0.077 12.4 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.6 OAG35175.1 - 2e-54 184.6 0.2 3.5e-54 183.8 0.2 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG35175.1 - 9.9e-49 165.4 1.4 1.2e-48 165.2 1.4 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG35175.1 - 2e-17 63.7 0.6 2.9e-17 63.2 0.6 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 OAG35175.1 - 0.0014 18.0 0.0 0.0042 16.5 0.0 1.7 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) THF_DHG_CYH_C PF02882.19 OAG35175.1 - 0.012 14.9 0.1 0.26 10.6 0.1 2.2 1 1 1 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_10 PF13460.6 OAG35175.1 - 0.051 13.5 0.6 0.071 13.0 0.6 1.4 1 1 0 1 1 1 0 NAD(P)H-binding Epimerase PF01370.21 OAG35175.1 - 0.12 11.8 0.1 0.24 10.8 0.1 1.5 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Reoviridae_Vp9 PF08978.10 OAG35175.1 - 0.17 11.0 0.0 0.23 10.6 0.0 1.2 1 0 0 1 1 1 0 Reoviridae VP9 NUFIP1 PF10453.9 OAG35175.1 - 0.19 11.6 0.7 0.3 11.0 0.1 1.6 2 0 0 2 2 2 0 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) Scytalone_dh PF02982.14 OAG35176.1 - 8.2e-45 152.5 1.6 9.7e-45 152.2 1.6 1.0 1 0 0 1 1 1 1 Scytalone dehydratase FAD_binding_4 PF01565.23 OAG35177.1 - 1.5e-17 63.6 1.1 3.6e-17 62.4 1.1 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 OAG35177.1 - 1.2e-11 44.6 0.1 2.4e-11 43.5 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like FAD_binding_3 PF01494.19 OAG35178.1 - 2.6e-18 66.4 0.1 6.5e-18 65.1 0.1 1.7 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 OAG35178.1 - 3.4e-05 24.0 0.7 0.00012 22.3 0.7 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 OAG35178.1 - 3.9e-05 23.1 0.6 0.19 11.0 0.0 2.7 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 OAG35178.1 - 7.2e-05 22.2 0.0 0.019 14.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAG35178.1 - 0.00043 19.5 0.3 0.00087 18.5 0.3 1.5 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 OAG35178.1 - 0.00045 19.4 0.2 0.0021 17.2 0.2 1.9 1 1 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 OAG35178.1 - 0.0016 18.1 2.3 0.0024 17.5 1.2 1.8 2 1 1 3 3 3 1 FAD dependent oxidoreductase SE PF08491.10 OAG35178.1 - 0.0033 16.5 0.0 0.0068 15.5 0.0 1.4 1 0 0 1 1 1 1 Squalene epoxidase Pyr_redox PF00070.27 OAG35178.1 - 0.023 15.2 0.1 0.066 13.8 0.1 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAG35178.1 - 0.056 13.4 0.7 0.81 9.7 0.5 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding WHH PF14414.6 OAG35178.1 - 0.15 11.9 0.4 0.6 10.0 0.1 2.0 2 0 0 2 2 2 0 A nuclease of the HNH/ENDO VII superfamily with conserved WHH HI0933_like PF03486.14 OAG35178.1 - 0.17 10.6 0.4 1 8.0 0.4 2.0 1 1 0 1 1 1 0 HI0933-like protein ketoacyl-synt PF00109.26 OAG35179.1 - 1.1e-79 267.6 0.0 1.9e-79 266.8 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain SAT PF16073.5 OAG35179.1 - 4e-72 242.8 0.1 2.8e-70 236.8 0.0 2.9 3 0 0 3 3 3 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Acyl_transf_1 PF00698.21 OAG35179.1 - 1.2e-40 139.9 0.0 2.2e-40 139.2 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 OAG35179.1 - 6.1e-29 100.4 1.6 1.1e-28 99.5 0.0 2.4 3 0 0 3 3 3 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.25 OAG35179.1 - 6.1e-26 90.6 4.5 3.1e-12 46.7 0.2 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site Thioesterase PF00975.20 OAG35179.1 - 5.8e-23 82.2 0.1 8.2e-22 78.5 0.0 2.5 2 0 0 2 2 2 1 Thioesterase domain PS-DH PF14765.6 OAG35179.1 - 1.4e-17 63.9 0.0 3e-17 62.8 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Thiolase_N PF00108.23 OAG35179.1 - 0.00093 18.6 0.0 0.0023 17.3 0.0 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain Abhydrolase_6 PF12697.7 OAG35179.1 - 0.001 19.7 0.6 0.024 15.2 0.1 2.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Telomere_Sde2_2 PF13297.6 OAG35179.1 - 0.012 15.3 0.5 1.4 8.6 0.1 3.4 3 0 0 3 3 3 0 Telomere stability C-terminal PGAP1 PF07819.13 OAG35179.1 - 0.079 12.7 0.0 0.26 11.0 0.0 1.8 2 0 0 2 2 2 0 PGAP1-like protein zf-C3HC4_5 PF17121.5 OAG35179.1 - 0.1 12.5 0.2 3 7.8 0.0 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) REC104 PF17378.2 OAG35179.1 - 0.2 11.4 0.0 0.41 10.4 0.0 1.4 1 0 0 1 1 1 0 Meiotic recombination protein REC104 Myb_DNA-binding PF00249.31 OAG35180.1 - 9.4e-24 83.4 12.9 8.4e-11 41.9 0.2 4.1 3 1 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OAG35180.1 - 1.6e-19 69.9 3.4 5.8e-11 42.5 0.1 4.1 1 1 3 4 4 4 4 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OAG35180.1 - 4.9e-08 32.8 0.1 9.6e-06 25.4 0.0 2.6 2 0 0 2 2 2 2 Myb DNA-binding like DUF3772 PF12607.8 OAG35180.1 - 0.052 13.3 0.4 0.16 11.7 0.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3772) Rap1_C PF11626.8 OAG35180.1 - 0.37 10.9 3.3 8.3 6.6 0.2 3.3 2 1 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain DUF4872 PF16169.5 OAG35180.1 - 0.48 10.2 4.9 2.6 7.8 0.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4872) adh_short_C2 PF13561.6 OAG35181.1 - 1.4e-60 204.7 0.5 1.7e-60 204.5 0.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG35181.1 - 5.6e-50 169.5 1.0 6.6e-50 169.3 1.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG35181.1 - 1.4e-12 47.9 0.4 1.9e-12 47.4 0.4 1.1 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 OAG35181.1 - 0.00039 20.4 0.1 0.00066 19.6 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 OAG35181.1 - 0.00067 18.9 0.2 0.00082 18.6 0.2 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein UDPG_MGDP_dh_N PF03721.14 OAG35181.1 - 0.0022 17.6 0.0 0.0057 16.2 0.1 1.7 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_25 PF13649.6 OAG35181.1 - 0.0029 18.3 0.0 0.0066 17.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.26 OAG35181.1 - 0.0051 16.8 0.0 0.0098 15.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_11 PF08241.12 OAG35181.1 - 0.038 14.6 0.0 0.08 13.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Epimerase PF01370.21 OAG35181.1 - 0.069 12.6 0.7 0.3 10.5 0.6 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family AAA_31 PF13614.6 OAG35181.1 - 0.07 13.0 0.0 0.43 10.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain Methyltransf_12 PF08242.12 OAG35181.1 - 0.13 13.0 0.0 0.29 11.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Thiolase_N PF00108.23 OAG35182.1 - 1.6e-64 217.8 0.1 2.1e-64 217.4 0.1 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 OAG35182.1 - 1.4e-41 141.0 0.3 2.9e-41 140.0 0.3 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 OAG35182.1 - 0.002 17.7 1.8 0.0042 16.7 0.9 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III_C PF08541.10 OAG35182.1 - 0.1 12.8 0.0 0.3 11.3 0.0 1.8 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal HSP70 PF00012.20 OAG35183.1 - 7.7e-162 539.6 0.7 7.7e-162 539.6 0.7 1.8 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 OAG35183.1 - 7.7e-09 34.8 0.0 1.8e-08 33.6 0.0 1.6 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 OAG35183.1 - 0.0039 17.6 3.8 0.36 11.3 0.1 3.3 3 2 0 3 3 3 2 Cell division protein FtsA DUF4288 PF14119.6 OAG35183.1 - 0.23 11.9 3.8 0.7 10.3 3.8 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4288) DUF45 PF01863.17 OAG35183.1 - 2.4 8.2 6.7 5.2 7.1 5.9 1.9 2 0 0 2 2 2 0 Protein of unknown function DUF45 Presenilin PF01080.17 OAG35183.1 - 8.1 5.1 8.7 14 4.3 8.7 1.3 1 0 0 1 1 1 0 Presenilin Chitin_synth_2 PF03142.15 OAG35184.1 - 5.6e-26 91.2 1.8 4.5e-23 81.7 1.8 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 OAG35184.1 - 2.5e-17 63.4 5.9 4.7e-17 62.6 5.9 1.4 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 OAG35184.1 - 2e-10 40.9 0.0 4.5e-10 39.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 OAG35184.1 - 0.04 13.7 0.1 4.6 7.0 0.0 2.6 2 0 0 2 2 2 0 Glycosyl transferase family 2 DASH_Ask1 PF08655.10 OAG35186.1 - 3e-30 103.9 0.2 5.1e-30 103.2 0.2 1.4 1 0 0 1 1 1 1 DASH complex subunit Ask1 Fasciclin PF02469.22 OAG35187.1 - 9.6e-22 77.6 7.1 7.5e-19 68.2 0.5 2.7 2 1 0 2 2 2 2 Fasciclin domain Colicin_Ia PF11504.8 OAG35187.1 - 0.61 10.2 2.5 20 5.3 0.1 3.1 3 0 0 3 3 3 0 Colicin Ia p450 PF00067.22 OAG35189.1 - 2.3e-62 211.3 0.0 2.9e-62 211.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Gal-3-0_sulfotr PF06990.11 OAG35189.1 - 0.1 11.5 0.1 0.17 10.7 0.1 1.2 1 0 0 1 1 1 0 Galactose-3-O-sulfotransferase SRP40_C PF05022.12 OAG35190.1 - 5.9e-18 65.5 3.2 2.3e-17 63.6 3.2 2.0 1 0 0 1 1 1 1 SRP40, C-terminal domain LisH PF08513.11 OAG35190.1 - 0.00072 19.4 0.0 0.0012 18.7 0.0 1.4 1 0 0 1 1 1 1 LisH Pyridoxal_deC PF00282.19 OAG35192.1 - 1.7e-17 63.2 0.0 2.8e-17 62.5 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 OAG35192.1 - 2.2e-07 30.2 0.0 4.4e-06 25.9 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 OAG35192.1 - 4.7e-05 22.9 0.1 9.7e-05 21.8 0.1 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family HMGL-like PF00682.19 OAG35193.1 - 7.8e-79 264.9 0.8 1.1e-78 264.4 0.8 1.2 1 0 0 1 1 1 1 HMGL-like ApbA_C PF08546.11 OAG35194.1 - 1e-27 96.8 0.0 1.6e-27 96.2 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 OAG35194.1 - 1.7e-26 92.7 0.0 2.2e-26 92.3 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.6 OAG35194.1 - 0.011 16.2 0.0 0.048 14.1 0.0 2.1 1 1 0 1 1 1 0 Putative NAD(P)-binding Sacchrp_dh_NADP PF03435.18 OAG35194.1 - 0.029 14.6 0.0 0.41 10.9 0.0 2.2 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Pyr_redox PF00070.27 OAG35194.1 - 0.15 12.7 0.0 0.6 10.7 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.16 OAG35195.1 - 1.2e-36 126.4 37.0 1.2e-36 126.4 37.0 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG35195.1 - 5.9e-14 51.8 21.0 9e-14 51.2 21.0 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter DUF4112 PF13430.6 OAG35195.1 - 0.053 13.8 0.6 0.22 11.8 0.3 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4112) ADH_N PF08240.12 OAG35196.1 - 2.8e-25 88.3 2.3 5.5e-25 87.4 2.3 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG35196.1 - 2.8e-21 75.8 0.1 4.5e-21 75.2 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAG35196.1 - 1.9e-05 25.7 0.0 3.1e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 OAG35196.1 - 0.019 14.9 0.0 0.044 13.7 0.0 1.6 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase ACP_syn_III_C PF08541.10 OAG35196.1 - 0.11 12.7 0.2 0.21 11.8 0.2 1.4 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal adh_short_C2 PF13561.6 OAG35197.1 - 5e-57 193.2 0.2 5.6e-57 193.0 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG35197.1 - 1.6e-38 132.2 0.1 1.9e-38 131.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG35197.1 - 3.7e-15 56.3 0.4 4.8e-15 55.9 0.4 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG35197.1 - 0.017 14.6 0.1 0.028 13.9 0.1 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family ADH_N PF08240.12 OAG35198.1 - 4.1e-27 94.2 0.6 6.7e-27 93.5 0.6 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG35198.1 - 7.3e-15 55.1 0.0 1.2e-14 54.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 OAG35198.1 - 3.1e-06 26.8 0.1 4.5e-06 26.3 0.1 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 OAG35198.1 - 0.00041 21.4 0.0 0.00069 20.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 OAG35198.1 - 0.0098 15.3 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_N_assoc PF13823.6 OAG35198.1 - 0.02 14.8 0.8 0.047 13.6 0.8 1.7 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-associated NAD_binding_7 PF13241.6 OAG35198.1 - 0.024 15.0 0.0 0.04 14.3 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Shikimate_DH PF01488.20 OAG35198.1 - 0.06 13.4 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NTP_transf_3 PF12804.7 OAG35198.1 - 0.065 13.6 0.1 0.13 12.6 0.1 1.5 1 0 0 1 1 1 0 MobA-like NTP transferase domain ADH_N_2 PF16884.5 OAG35198.1 - 0.11 12.5 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase TrkA_N PF02254.18 OAG35198.1 - 0.16 12.2 0.0 0.28 11.5 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain TRI12 PF06609.13 OAG35199.1 - 1.6e-33 116.1 20.4 2.3e-33 115.5 20.4 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG35199.1 - 2.2e-24 86.1 49.2 3.9e-24 85.2 48.0 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG35199.1 - 4.5e-06 25.8 10.3 4.5e-06 25.8 10.3 3.2 3 0 0 3 3 3 2 Sugar (and other) transporter EthD PF07110.11 OAG35200.1 - 1.4e-18 67.8 0.0 2e-18 67.3 0.0 1.2 1 0 0 1 1 1 1 EthD domain Glyoxalase_4 PF13669.6 OAG35201.1 - 0.13 12.6 0.0 0.65 10.3 0.0 2.1 3 0 0 3 3 3 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily p450 PF00067.22 OAG35202.1 - 2.6e-68 230.9 0.0 3.1e-68 230.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 TRI12 PF06609.13 OAG35203.1 - 5.5e-84 282.7 16.5 6.9e-84 282.3 16.5 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG35203.1 - 7.3e-17 61.3 48.4 9e-17 61.0 46.5 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily Fungal_trans PF04082.18 OAG35204.1 - 1.9e-20 73.0 3.4 3.5e-20 72.1 3.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain FMO-like PF00743.19 OAG35205.1 - 4.1e-18 65.1 0.0 1.3e-13 50.3 0.0 3.1 2 1 1 3 3 3 3 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OAG35205.1 - 3.1e-07 30.5 0.0 6.7e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 OAG35205.1 - 0.00016 21.0 0.0 0.0028 17.0 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAG35205.1 - 0.00034 19.9 0.0 0.14 11.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAG35205.1 - 0.023 14.3 0.0 1.7 8.1 0.0 3.1 1 1 1 2 2 2 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 OAG35205.1 - 0.025 14.5 0.7 0.22 11.5 0.0 2.8 4 0 0 4 4 4 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 OAG35205.1 - 0.071 12.2 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.17 OAG35205.1 - 0.2 10.9 0.0 0.52 9.5 0.0 1.6 2 0 0 2 2 2 0 Thi4 family Globin PF00042.22 OAG35205.1 - 0.25 11.9 1.2 11 6.7 0.1 2.4 2 0 0 2 2 2 0 Globin adh_short_C2 PF13561.6 OAG35206.1 - 2.9e-53 180.8 1.6 3.7e-53 180.5 1.6 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG35206.1 - 2e-45 154.7 2.2 3e-45 154.1 2.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG35206.1 - 3.4e-09 36.9 2.0 7.1e-09 35.8 0.2 2.0 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 OAG35206.1 - 0.00015 21.3 1.2 0.0025 17.3 0.2 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OAG35206.1 - 0.00044 19.4 0.3 0.0075 15.3 0.2 2.1 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family ThiF PF00899.21 OAG35206.1 - 0.014 14.8 3.3 0.18 11.1 0.3 2.1 1 1 1 2 2 2 0 ThiF family FMO-like PF00743.19 OAG35207.1 - 2.4e-15 56.0 0.0 5.4e-15 54.8 0.0 1.5 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OAG35207.1 - 9.5e-12 44.8 0.0 1.7e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAG35207.1 - 3e-06 26.7 0.0 6e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG35207.1 - 8.9e-06 25.8 0.0 2.2e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 OAG35207.1 - 0.00036 19.8 0.0 0.0032 16.7 0.0 2.3 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 OAG35207.1 - 0.00075 18.8 0.0 0.0031 16.8 0.0 1.9 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 OAG35207.1 - 0.15 10.8 0.1 0.33 9.6 0.1 1.5 1 0 0 1 1 1 0 HI0933-like protein Cupin_2 PF07883.11 OAG35208.1 - 6.1e-26 89.9 4.7 1.1e-12 47.5 0.5 2.2 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.19 OAG35208.1 - 6.7e-13 48.7 4.3 8.6e-07 28.9 0.3 2.2 2 0 0 2 2 2 2 AraC-like ligand binding domain MannoseP_isomer PF01050.18 OAG35208.1 - 5.3e-08 32.9 0.0 0.0013 18.7 0.0 2.1 2 0 0 2 2 2 2 Mannose-6-phosphate isomerase Cupin_1 PF00190.22 OAG35208.1 - 6.4e-07 29.1 0.6 0.0011 18.7 0.0 2.9 2 1 0 2 2 2 2 Cupin DMSP_lyase PF16867.5 OAG35208.1 - 2.4e-06 27.3 0.3 0.00031 20.4 0.1 2.2 2 0 0 2 2 2 2 Dimethlysulfonioproprionate lyase Auxin_BP PF02041.16 OAG35208.1 - 3.1e-05 23.7 0.1 0.12 12.0 0.0 2.4 2 0 0 2 2 2 2 Auxin binding protein CENP-C_C PF11699.8 OAG35208.1 - 0.0033 17.6 0.0 1.1 9.5 0.0 2.2 2 0 0 2 2 2 2 Mif2/CENP-C like Cupin_3 PF05899.12 OAG35208.1 - 0.0047 16.6 0.1 0.19 11.5 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF861) p450 PF00067.22 OAG35209.1 - 8.3e-45 153.4 0.7 1.2e-44 152.9 0.7 1.2 1 0 0 1 1 1 1 Cytochrome P450 adh_short_C2 PF13561.6 OAG35211.1 - 5.7e-44 150.4 3.9 2.8e-42 144.9 0.1 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG35211.1 - 3.5e-33 114.7 1.3 9.8e-32 110.0 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase ADH_zinc_N PF00107.26 OAG35211.1 - 3.4e-21 75.6 1.8 7e-21 74.6 1.3 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG35211.1 - 9.5e-10 38.3 0.2 7.5e-08 32.2 0.1 2.7 2 1 1 3 3 3 2 Alcohol dehydrogenase GroES-like domain KR PF08659.10 OAG35211.1 - 8.6e-05 22.5 0.7 0.084 12.8 0.0 2.3 2 0 0 2 2 2 2 KR domain AlaDh_PNT_C PF01262.21 OAG35211.1 - 0.00024 20.5 0.8 0.00049 19.5 0.8 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Epimerase PF01370.21 OAG35211.1 - 0.0007 19.1 0.3 0.15 11.5 0.0 2.4 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.19 OAG35211.1 - 0.00077 18.9 0.1 0.0018 17.7 0.1 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_25 PF13649.6 OAG35211.1 - 0.038 14.7 0.1 0.13 13.0 0.1 1.9 1 0 0 1 1 1 0 Methyltransferase domain NAD_binding_2 PF03446.15 OAG35211.1 - 0.1 12.7 0.1 0.32 11.2 0.1 1.9 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase adh_short_C2 PF13561.6 OAG35212.1 - 2.1e-49 168.2 4.6 5.2e-48 163.6 4.6 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG35212.1 - 1.7e-38 132.0 6.6 9.5e-38 129.6 6.6 1.9 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG35212.1 - 7.1e-10 39.1 0.6 1.1e-09 38.4 0.6 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG35212.1 - 0.0037 16.8 0.5 0.011 15.2 0.4 1.8 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family YopE_N PF09020.10 OAG35212.1 - 0.031 14.5 0.0 0.058 13.6 0.0 1.5 1 0 0 1 1 1 0 YopE, N terminal 3HCDH_N PF02737.18 OAG35212.1 - 0.066 13.1 0.3 0.11 12.4 0.3 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HHH_5 PF14520.6 OAG35212.1 - 0.22 12.2 1.2 2.8 8.6 0.9 2.3 1 1 1 2 2 2 0 Helix-hairpin-helix domain Abhydrolase_3 PF07859.13 OAG35213.1 - 1.8e-56 191.3 0.2 2.4e-56 191.0 0.2 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 OAG35213.1 - 0.0012 17.9 0.0 0.0022 16.9 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family Hydrolase_4 PF12146.8 OAG35213.1 - 0.0019 17.5 0.1 0.026 13.8 0.1 2.0 1 1 0 2 2 2 1 Serine aminopeptidase, S33 Cutinase PF01083.22 OAG35213.1 - 0.016 15.2 0.0 0.026 14.5 0.0 1.3 1 0 0 1 1 1 0 Cutinase DLH PF01738.18 OAG35213.1 - 0.11 12.1 0.2 1.3 8.6 0.0 2.3 2 1 1 3 3 3 0 Dienelactone hydrolase family Peptidase_S9 PF00326.21 OAG35213.1 - 0.16 11.4 0.0 1.2 8.5 0.0 2.2 1 1 0 1 1 1 0 Prolyl oligopeptidase family AtuA PF07287.11 OAG35214.1 - 5.6e-116 387.1 0.0 6.9e-116 386.8 0.0 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA EthD PF07110.11 OAG35215.1 - 1.2e-13 52.0 0.4 1.6e-13 51.6 0.4 1.2 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 OAG35215.1 - 4.4e-06 27.1 0.0 6e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Methylmuconolactone methyl-isomerase TRI12 PF06609.13 OAG35216.1 - 1.1e-57 195.8 22.7 1.4e-57 195.4 22.7 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG35216.1 - 4.7e-19 68.5 55.7 4.7e-18 65.2 14.1 4.0 1 1 3 4 4 4 3 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG35216.1 - 2e-08 33.5 9.1 2e-08 33.5 9.1 3.8 2 1 2 4 4 4 1 Sugar (and other) transporter Aldedh PF00171.22 OAG35217.1 - 3.8e-144 480.6 0.0 4.3e-144 480.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 OAG35217.1 - 0.021 13.9 0.1 0.036 13.1 0.1 1.3 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) Siva PF05458.12 OAG35217.1 - 0.057 13.1 0.4 0.1 12.3 0.4 1.3 1 0 0 1 1 1 0 Cd27 binding protein (Siva) DUF1487 PF07368.11 OAG35217.1 - 0.095 12.1 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1487) DUF3425 PF11905.8 OAG35218.1 - 3.3e-12 46.5 0.2 3.3e-12 46.5 0.2 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3425) Cyclase PF04199.13 OAG35219.1 - 5.3e-16 59.1 0.0 1.8e-15 57.4 0.0 1.9 2 0 0 2 2 2 1 Putative cyclase Fungal_trans PF04082.18 OAG35219.1 - 2.7e-15 56.1 2.0 4.4e-15 55.4 2.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain CbtA_toxin PF06755.12 OAG35219.1 - 0.071 13.1 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 CbtA_toxin of type IV toxin-antitoxin system adh_short_C2 PF13561.6 OAG35220.1 - 1.5e-42 145.8 0.0 1.6e-42 145.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG35220.1 - 3.4e-39 134.3 0.0 3.8e-39 134.2 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG35220.1 - 1.8e-09 37.8 0.1 2.4e-09 37.4 0.1 1.1 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 OAG35220.1 - 0.018 14.3 0.0 0.064 12.6 0.0 1.9 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NmrA PF05368.13 OAG35221.1 - 1.2e-20 74.0 0.0 1.7e-20 73.6 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG35221.1 - 1.3e-15 57.7 0.0 3.7e-15 56.3 0.0 1.7 1 1 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 OAG35221.1 - 9.9e-05 22.6 0.0 0.00055 20.2 0.0 2.0 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain KR PF08659.10 OAG35221.1 - 0.0006 19.8 0.0 0.0013 18.6 0.0 1.6 1 1 0 1 1 1 1 KR domain TrkA_N PF02254.18 OAG35221.1 - 0.026 14.8 0.2 0.079 13.2 0.0 1.8 2 0 0 2 2 2 0 TrkA-N domain PglD_N PF17836.1 OAG35221.1 - 0.051 14.2 0.0 0.096 13.3 0.0 1.4 1 0 0 1 1 1 0 PglD N-terminal domain DapB_N PF01113.20 OAG35221.1 - 0.068 13.3 0.1 0.18 12.0 0.0 1.7 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus 3Beta_HSD PF01073.19 OAG35221.1 - 0.085 11.9 0.1 0.29 10.1 0.1 1.8 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 OAG35221.1 - 0.23 10.9 0.5 1 8.8 0.1 2.2 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family MFS_1 PF07690.16 OAG35222.1 - 1.4e-45 155.8 41.8 1.8e-45 155.4 37.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG35222.1 - 3.2e-09 36.2 21.1 7e-09 35.1 20.9 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter Glyoxalase_4 PF13669.6 OAG35223.1 - 1.5e-09 38.1 0.0 3.2e-09 37.0 0.0 1.5 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase PF00903.25 OAG35223.1 - 9.5e-09 35.5 0.0 5.6e-08 33.0 0.0 1.9 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 OAG35223.1 - 2.7e-08 34.5 0.0 2.9e-07 31.2 0.0 2.0 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_3 PF13468.6 OAG35223.1 - 7.1e-05 23.0 0.0 0.0041 17.3 0.0 2.2 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.25 OAG35224.1 - 0.02 15.1 0.0 0.17 12.1 0.0 2.5 2 1 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily zf-BED PF02892.15 OAG35224.1 - 0.11 12.6 0.5 0.91 9.6 0.0 2.3 2 0 0 2 2 2 0 BED zinc finger Pyr_redox_2 PF07992.14 OAG35225.1 - 1.3e-13 50.8 0.0 3.5e-12 46.2 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 OAG35225.1 - 3.2e-13 48.9 0.1 1.3e-11 43.7 0.0 2.1 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OAG35225.1 - 2.2e-12 46.9 0.0 1.9e-10 40.5 0.0 2.7 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG35225.1 - 6.8e-12 45.2 0.1 1.9e-06 27.2 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 OAG35225.1 - 1.2e-10 41.5 0.3 2.2e-08 34.2 0.0 3.4 3 1 0 3 3 3 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 OAG35225.1 - 1.7e-06 28.1 0.6 0.078 13.0 0.0 4.0 3 1 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 OAG35225.1 - 3.9e-06 27.3 0.2 0.0068 16.9 0.1 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAG35225.1 - 0.00017 20.9 0.1 0.036 13.3 0.0 2.7 3 0 0 3 3 3 1 Thi4 family GIDA PF01134.22 OAG35225.1 - 0.00026 20.2 1.7 0.058 12.5 0.1 2.6 3 0 0 3 3 3 2 Glucose inhibited division protein A Lycopene_cycl PF05834.12 OAG35225.1 - 0.0027 16.8 0.0 0.066 12.2 0.0 2.7 3 0 0 3 3 3 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 OAG35225.1 - 0.0027 16.9 0.0 0.0052 15.9 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAG35225.1 - 0.0032 17.1 2.7 0.019 14.6 0.1 3.1 3 1 1 4 4 4 1 FAD dependent oxidoreductase ThiF PF00899.21 OAG35225.1 - 0.042 13.2 0.0 1.4 8.2 0.0 2.3 2 0 0 2 2 2 0 ThiF family HI0933_like PF03486.14 OAG35225.1 - 0.043 12.5 0.6 0.29 9.8 0.1 2.2 2 0 0 2 2 2 0 HI0933-like protein AlaDh_PNT_C PF01262.21 OAG35225.1 - 0.047 13.0 0.2 0.29 10.4 0.0 2.2 2 1 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.16 OAG35225.1 - 0.058 13.0 0.9 11 5.7 0.2 2.5 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.6 OAG35225.1 - 0.066 13.7 0.0 5.8 7.4 0.0 2.8 3 0 0 3 3 3 0 Putative NAD(P)-binding Shikimate_DH PF01488.20 OAG35225.1 - 0.14 12.2 0.9 8.6 6.4 0.0 3.0 4 0 0 4 4 4 0 Shikimate / quinate 5-dehydrogenase APH PF01636.23 OAG35226.1 - 4.7e-06 26.7 0.2 0.0017 18.3 0.0 2.5 2 1 0 2 2 2 2 Phosphotransferase enzyme family Ank_2 PF12796.7 OAG35227.1 - 1.9e-33 114.9 1.0 5.8e-12 46.0 0.0 5.8 4 1 1 6 6 6 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAG35227.1 - 4.9e-24 84.4 5.8 8.2e-05 23.1 0.0 6.9 7 1 0 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG35227.1 - 1.6e-17 61.8 11.9 0.12 13.0 0.0 10.2 11 0 0 11 11 11 5 Ankyrin repeat Ank PF00023.30 OAG35227.1 - 2.9e-14 52.8 20.1 0.038 14.4 0.0 9.1 10 0 0 10 10 10 5 Ankyrin repeat Ank_5 PF13857.6 OAG35227.1 - 2.4e-13 50.0 9.2 0.065 13.6 0.0 8.0 5 2 3 8 8 8 4 Ankyrin repeats (many copies) Clr5 PF14420.6 OAG35227.1 - 8.8e-09 35.5 0.5 1.8e-08 34.5 0.5 1.5 1 0 0 1 1 1 1 Clr5 domain TRI12 PF06609.13 OAG35228.1 - 1.4e-22 79.8 25.1 2.1e-22 79.3 25.1 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG35228.1 - 1.5e-20 73.4 51.3 4.1e-20 72.0 47.2 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.16 OAG35229.1 - 7.7e-43 146.8 46.5 1.2e-42 146.2 46.5 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG35229.1 - 7.7e-13 48.1 27.8 1.4e-12 47.3 12.1 3.2 2 1 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 OAG35229.1 - 5.5e-05 21.8 22.2 0.00012 20.7 11.6 3.1 2 1 1 3 3 3 3 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 OAG35229.1 - 0.15 10.3 12.5 0.036 12.3 5.1 2.6 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Phage_holin_3_2 PF04550.12 OAG35229.1 - 0.4 11.2 4.3 3.8 8.1 2.3 3.0 2 0 0 2 2 2 0 Phage holin family 2 SGL PF08450.12 OAG35230.1 - 2.2e-21 76.6 0.0 4.7e-21 75.5 0.0 1.6 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 OAG35230.1 - 0.0045 17.1 0.0 0.046 13.9 0.0 2.6 3 0 0 3 3 3 1 Arylesterase PD40 PF07676.12 OAG35230.1 - 0.02 14.8 0.1 0.047 13.6 0.1 1.6 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat NHL PF01436.21 OAG35230.1 - 0.041 13.9 1.7 31 4.8 0.0 5.0 6 1 0 6 6 6 0 NHL repeat TRI12 PF06609.13 OAG35231.1 - 1.2e-40 139.6 27.5 1.3e-40 139.4 27.5 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG35231.1 - 2.5e-26 92.4 56.4 2.1e-25 89.4 56.4 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.16 OAG35232.1 - 9.9e-43 146.4 51.1 9.9e-43 146.4 51.1 1.7 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG35232.1 - 2.8e-14 52.8 36.1 9.2e-14 51.1 12.5 3.1 3 0 0 3 3 3 3 Sugar (and other) transporter GAS PF13851.6 OAG35233.1 - 0.0052 16.2 1.2 0.0064 15.9 1.2 1.2 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding HAUS6_N PF14661.6 OAG35233.1 - 0.009 15.6 0.9 0.01 15.5 0.9 1.1 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 6 N-terminus Wtap PF17098.5 OAG35233.1 - 0.015 15.2 1.2 0.021 14.8 1.2 1.2 1 0 0 1 1 1 0 WTAP/Mum2p family Spc7 PF08317.11 OAG35233.1 - 0.018 14.0 1.1 0.022 13.7 1.1 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein PH_4 PF15404.6 OAG35233.1 - 0.031 14.1 0.6 0.036 13.8 0.6 1.1 1 0 0 1 1 1 0 Pleckstrin homology domain DUF3450 PF11932.8 OAG35233.1 - 0.032 13.5 1.2 0.04 13.2 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF4407 PF14362.6 OAG35233.1 - 0.043 13.2 0.7 0.045 13.1 0.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Cluap1 PF10234.9 OAG35233.1 - 0.069 12.5 1.8 0.083 12.3 1.8 1.1 1 0 0 1 1 1 0 Clusterin-associated protein-1 BRE1 PF08647.11 OAG35233.1 - 0.079 13.0 2.4 0.11 12.5 1.9 1.5 1 1 0 1 1 1 0 BRE1 E3 ubiquitin ligase DUF4349 PF14257.6 OAG35233.1 - 0.085 12.3 0.1 0.086 12.3 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) Lzipper-MIP1 PF14389.6 OAG35233.1 - 0.09 13.1 0.3 0.22 11.9 0.1 1.5 1 1 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 DivIC PF04977.15 OAG35233.1 - 0.77 9.6 3.2 0.61 9.9 0.4 2.0 1 1 1 2 2 2 0 Septum formation initiator ECH_1 PF00378.20 OAG35234.1 - 2.2e-28 99.2 0.0 2.8e-28 98.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAG35234.1 - 7.1e-11 42.2 0.0 7.8e-11 42.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ACOX PF01756.19 OAG35235.1 - 2.7e-41 141.1 0.2 6.2e-41 139.9 0.1 1.6 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 OAG35235.1 - 1.2e-25 90.5 0.1 3.2e-25 89.1 0.1 1.8 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 OAG35235.1 - 4.5e-09 36.4 0.0 1.1e-08 35.2 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 OAG35235.1 - 0.055 13.7 1.9 0.97 9.6 1.9 2.3 1 1 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain AMP-binding PF00501.28 OAG35236.1 - 4.3e-54 183.7 0.0 5.3e-54 183.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG35236.1 - 1.4e-10 41.9 0.0 4.6e-10 40.3 0.0 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain PAN_1 PF00024.26 OAG35237.1 - 0.027 14.4 1.3 0.24 11.4 1.3 2.8 1 0 0 1 1 1 0 PAN domain LAMTOR PF15454.6 OAG35238.1 - 7.2e-11 42.5 0.0 1.8e-10 41.3 0.0 1.7 1 1 0 1 1 1 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator CMD PF02627.20 OAG35239.1 - 6.2e-07 29.4 0.1 0.00053 20.0 0.0 2.3 1 1 1 2 2 2 2 Carboxymuconolactone decarboxylase family CPSase_L_D3 PF02787.19 OAG35239.1 - 0.1 13.0 0.0 0.46 10.8 0.0 1.9 1 1 1 2 2 2 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain DIOX_N PF14226.6 OAG35240.1 - 3e-26 92.5 0.0 5.8e-26 91.6 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OAG35240.1 - 4.4e-21 75.3 0.3 1.3e-20 73.7 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Zn_clus PF00172.18 OAG35241.1 - 2e-09 37.4 10.9 2e-09 37.4 10.9 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MOSC_N PF03476.16 OAG35242.1 - 7.3e-22 77.5 0.0 1.4e-21 76.6 0.0 1.5 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.17 OAG35242.1 - 1.1e-21 77.2 0.0 2.2e-21 76.2 0.0 1.5 1 0 0 1 1 1 1 MOSC domain PseudoU_synth_1 PF01416.20 OAG35243.1 - 5e-10 39.8 0.0 1.2e-08 35.4 0.0 2.4 2 0 0 2 2 2 1 tRNA pseudouridine synthase Catalase-rel PF06628.12 OAG35243.1 - 0.12 12.6 0.6 3.3 8.0 0.3 2.6 2 0 0 2 2 2 0 Catalase-related immune-responsive DUF4441 PF14536.6 OAG35243.1 - 0.2 11.9 0.0 0.2 11.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4441) RNA_pol_Rpb2_6 PF00562.28 OAG35244.1 - 9.9e-115 383.7 0.0 1.3e-114 383.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 OAG35244.1 - 5.1e-38 130.6 0.0 1.1e-37 129.5 0.0 1.5 2 0 0 2 2 2 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 OAG35244.1 - 8.1e-29 99.6 0.0 1.9e-28 98.4 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_2 PF04561.14 OAG35244.1 - 7.7e-26 90.9 0.0 1.3e-25 90.2 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpa2_4 PF06883.12 OAG35244.1 - 5e-24 84.1 0.0 1.2e-23 82.9 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_7 PF04560.20 OAG35244.1 - 2.2e-15 56.8 0.0 7.5e-15 55.1 0.1 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 ACC_central PF08326.12 OAG35245.1 - 2e-281 935.5 0.0 2.7e-281 935.1 0.0 1.2 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.22 OAG35245.1 - 9.5e-188 624.8 0.0 1.6e-187 624.1 0.0 1.4 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 OAG35245.1 - 8.3e-53 179.0 0.0 1.5e-52 178.2 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 OAG35245.1 - 3.4e-28 98.4 0.1 7.3e-28 97.3 0.1 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 OAG35245.1 - 3.2e-25 88.3 0.0 2e-21 76.1 0.0 3.3 3 0 0 3 3 3 2 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 OAG35245.1 - 2.4e-16 59.3 0.1 5.7e-16 58.1 0.1 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 OAG35245.1 - 0.0039 16.8 0.0 0.0091 15.5 0.0 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 OAG35245.1 - 0.0041 17.2 0.0 0.013 15.5 0.0 1.9 1 0 0 1 1 1 1 ATP-grasp domain GxGYxYP_N PF16216.5 OAG35245.1 - 0.016 15.4 0.0 0.034 14.3 0.0 1.4 1 0 0 1 1 1 0 GxGYxY sequence motif in domain of unknown function N-terminal ATP-grasp PF02222.22 OAG35245.1 - 0.02 14.4 0.0 0.047 13.3 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain ATPgrasp_Ter PF15632.6 OAG35245.1 - 0.067 12.9 0.0 0.19 11.5 0.0 1.7 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon SNF2_N PF00176.23 OAG35246.1 - 2.3e-20 72.6 0.5 1.1e-19 70.4 0.5 2.0 1 1 0 1 1 1 1 SNF2 family N-terminal domain DNA_methylase PF00145.17 OAG35246.1 - 9.2e-09 35.1 1.6 5.6e-08 32.5 0.0 2.7 3 0 0 3 3 3 1 C-5 cytosine-specific DNA methylase DUF2052 PF09747.9 OAG35246.1 - 0.0032 17.6 4.3 0.012 15.8 2.9 2.4 2 0 0 2 2 2 1 Coiled-coil domain containing protein (DUF2052) Eapp_C PF10238.9 OAG35246.1 - 2.8 8.0 6.7 8.6 6.4 1.6 2.8 2 0 0 2 2 2 0 E2F-associated phosphoprotein Band_7 PF01145.25 OAG35247.1 - 5.6e-23 81.9 5.0 1.1e-22 81.0 5.0 1.5 1 1 0 1 1 1 1 SPFH domain / Band 7 family Methyltransf_5 PF01795.19 OAG35247.1 - 0.15 11.5 3.1 0.24 10.9 3.1 1.4 1 1 0 1 1 1 0 MraW methylase family CSTF2_hinge PF14327.6 OAG35248.1 - 5.1e-32 110.2 4.0 5.1e-32 110.2 4.0 2.6 3 0 0 3 3 3 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.22 OAG35248.1 - 8.3e-20 70.4 0.2 1.3e-19 69.8 0.2 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.6 OAG35248.1 - 4e-10 39.1 3.1 4e-10 39.1 3.1 2.6 2 0 0 2 2 2 1 Transcription termination and cleavage factor C-terminal RRM_7 PF16367.5 OAG35248.1 - 0.0014 18.7 0.4 0.1 12.7 0.0 2.4 1 1 1 2 2 2 1 RNA recognition motif RRM_occluded PF16842.5 OAG35248.1 - 0.044 13.6 0.0 0.11 12.3 0.0 1.7 1 1 0 1 1 1 0 Occluded RNA-recognition motif Utp12 PF04003.12 OAG35248.1 - 0.17 12.2 0.1 0.33 11.3 0.1 1.4 1 0 0 1 1 1 0 Dip2/Utp12 Family Ran-binding PF05508.11 OAG35249.1 - 1e-123 412.3 0.1 1.3e-123 412.0 0.1 1.1 1 0 0 1 1 1 1 RanGTP-binding protein CorA PF01544.18 OAG35249.1 - 0.031 13.6 0.7 0.054 12.8 0.7 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein GTP_EFTU PF00009.27 OAG35250.1 - 6.2e-41 140.1 0.0 9.3e-41 139.5 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 OAG35250.1 - 1.7e-30 105.6 0.1 8.7e-30 103.3 0.1 2.3 3 0 0 3 3 3 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 OAG35250.1 - 0.00019 21.8 0.1 0.00043 20.6 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 OAG35250.1 - 0.00043 20.4 0.1 0.0038 17.3 0.1 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase RRM_1 PF00076.22 OAG35251.1 - 1.7e-32 111.1 0.1 5.6e-14 51.7 0.0 3.6 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OAG35251.1 - 1.9e-07 30.9 0.1 0.0045 16.8 0.0 3.3 3 0 0 3 3 3 2 Occluded RNA-recognition motif BRAP2 PF07576.12 OAG35251.1 - 0.19 11.9 0.0 11 6.3 0.0 2.9 3 0 0 3 3 3 0 BRCA1-associated protein 2 SKG6 PF08693.10 OAG35251.1 - 5.1 6.6 5.9 11 5.5 5.9 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Peptidase_M20 PF01546.28 OAG35252.1 - 5.8e-27 94.7 0.0 8.7e-27 94.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 OAG35252.1 - 3.7e-14 52.6 0.0 5.8e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Fungal_trans_2 PF11951.8 OAG35253.1 - 3.3e-35 121.6 0.9 7.6e-35 120.4 0.9 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.18 OAG35253.1 - 0.15 11.0 0.1 0.26 10.3 0.1 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain AA_permease_2 PF13520.6 OAG35254.1 - 2e-47 162.0 44.6 2.4e-47 161.7 44.6 1.0 1 0 0 1 1 1 1 Amino acid permease OGG_N PF07934.12 OAG35255.1 - 1.4e-33 115.6 0.0 2.5e-33 114.7 0.0 1.5 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 OAG35255.1 - 1.1e-15 58.0 0.0 2e-15 57.2 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 OAG35255.1 - 0.0029 17.4 0.0 0.0059 16.4 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif DUF1840 PF08895.11 OAG35255.1 - 0.13 12.6 0.0 0.77 10.1 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) Rax2 PF12768.7 OAG35257.1 - 1.4e-64 217.5 0.2 6.8e-63 212.0 0.0 3.5 3 2 0 4 4 4 1 Cortical protein marker for cell polarity Reg_prop PF07494.11 OAG35257.1 - 0.0095 16.0 0.1 16 6.2 0.1 4.6 3 0 0 3 3 3 1 Two component regulator propeller NB-ARC PF00931.22 OAG35258.1 - 0.0018 17.5 0.0 0.003 16.8 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain FerA PF08165.11 OAG35258.1 - 0.1 12.6 0.1 2.5 8.1 0.1 2.4 2 1 0 2 2 2 0 FerA (NUC095) domain DUF676 PF05057.14 OAG35259.1 - 2.1e-06 27.4 0.0 2.8e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 OAG35259.1 - 0.00088 19.9 0.2 0.0016 19.1 0.2 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG35259.1 - 0.0017 17.6 0.1 0.0042 16.4 0.0 1.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Cutinase PF01083.22 OAG35259.1 - 0.0022 18.0 0.0 0.0034 17.4 0.0 1.3 1 0 0 1 1 1 1 Cutinase Ser_hydrolase PF06821.13 OAG35259.1 - 0.091 12.6 0.0 0.22 11.3 0.0 1.7 1 1 1 2 2 2 0 Serine hydrolase LIDHydrolase PF10230.9 OAG35259.1 - 0.15 11.6 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase DapB_N PF01113.20 OAG35261.1 - 1.2e-06 28.7 0.0 2.4e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus EthD PF07110.11 OAG35263.1 - 3.1e-16 60.3 0.0 4.3e-16 59.8 0.0 1.2 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 OAG35263.1 - 2.5e-06 27.9 0.0 3.5e-06 27.4 0.0 1.4 1 1 0 1 1 1 1 Methylmuconolactone methyl-isomerase Chalcone PF02431.15 OAG35263.1 - 0.041 13.3 0.0 0.19 11.1 0.0 1.8 2 0 0 2 2 2 0 Chalcone-flavanone isomerase p450 PF00067.22 OAG35264.1 - 5.1e-74 249.7 0.0 5.9e-74 249.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4744 PF15918.5 OAG35264.1 - 0.0019 19.0 0.2 0.0049 17.7 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4744) adh_short PF00106.25 OAG35265.1 - 5.6e-38 130.4 0.0 6.8e-38 130.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG35265.1 - 2.1e-20 73.3 0.0 2.8e-20 72.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG35265.1 - 1.4e-05 25.1 0.0 4.2e-05 23.5 0.0 1.6 2 0 0 2 2 2 1 KR domain 2-Hacid_dh_C PF02826.19 OAG35265.1 - 0.031 13.6 0.0 0.055 12.8 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Glyoxalase PF00903.25 OAG35266.1 - 1.4e-14 54.4 0.1 2.2e-14 53.8 0.1 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 OAG35266.1 - 0.0011 19.7 0.0 0.0023 18.7 0.0 1.5 1 1 0 1 1 1 1 Glyoxalase-like domain DUF3237 PF11578.8 OAG35267.1 - 6e-24 84.6 0.2 1e-23 83.9 0.2 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3237) DUF4440 PF14534.6 OAG35267.1 - 0.00079 19.8 0.0 0.0025 18.2 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4440) SnoaL_3 PF13474.6 OAG35267.1 - 0.04 14.2 0.0 0.086 13.1 0.0 1.5 1 0 0 1 1 1 0 SnoaL-like domain FAA_hydrolase PF01557.18 OAG35268.1 - 6.3e-57 192.7 0.0 7.7e-57 192.5 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAD_binding_3 PF01494.19 OAG35269.1 - 4.4e-62 210.4 0.0 7.2e-62 209.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 OAG35269.1 - 0.00024 19.9 0.0 0.0011 17.7 0.0 1.9 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 OAG35269.1 - 0.0058 15.9 0.0 0.022 14.0 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAG35269.1 - 0.0065 15.6 0.0 0.39 9.7 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 OAG35269.1 - 0.0078 16.7 0.0 0.05 14.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAG35269.1 - 0.013 15.1 0.4 0.068 12.8 0.2 2.2 1 1 1 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG35269.1 - 0.014 14.7 0.0 0.063 12.5 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG35269.1 - 0.12 12.6 0.0 0.38 11.0 0.0 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain adh_short PF00106.25 OAG35270.1 - 1.5e-34 119.2 0.0 2.7e-34 118.3 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG35270.1 - 3.3e-24 85.7 0.0 8.5e-24 84.4 0.0 1.6 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG35270.1 - 7.1e-06 26.0 0.0 1.6e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 OAG35270.1 - 0.003 16.6 0.0 0.0055 15.7 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family PA PF02225.22 OAG35270.1 - 0.039 14.0 0.2 0.083 12.9 0.2 1.6 1 0 0 1 1 1 0 PA domain NAD_binding_7 PF13241.6 OAG35270.1 - 0.052 14.0 0.1 0.1 13.1 0.1 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding p450 PF00067.22 OAG35271.1 - 2.3e-61 207.9 0.0 1.3e-59 202.2 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 OAG35272.1 - 1.7e-56 191.9 0.0 2.2e-56 191.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.18 OAG35273.1 - 1.2e-21 76.9 0.1 2e-21 76.2 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain BLOC1_2 PF10046.9 OAG35274.1 - 0.28 11.5 1.5 0.86 9.9 0.4 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 AMP-binding PF00501.28 OAG35275.1 - 5.1e-45 153.8 0.0 7.6e-45 153.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG35275.1 - 2.9e-05 24.9 0.0 6.7e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PsbR PF04725.12 OAG35275.1 - 0.12 12.7 0.3 0.3 11.5 0.3 1.6 1 0 0 1 1 1 0 Photosystem II 10 kDa polypeptide PsbR tify PF06200.14 OAG35275.1 - 0.19 11.1 0.1 0.46 9.8 0.1 1.6 1 0 0 1 1 1 0 tify domain FAD_binding_3 PF01494.19 OAG35276.1 - 3.8e-17 62.6 0.0 2.3e-16 60.0 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAG35276.1 - 4.1e-09 36.5 0.0 0.00098 18.8 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG35276.1 - 2.1e-07 30.5 0.0 0.00022 20.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG35276.1 - 4e-06 26.3 0.1 0.03 13.6 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAG35276.1 - 1.3e-05 24.5 0.0 0.00027 20.1 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 OAG35276.1 - 1.9e-05 24.8 0.1 5.6e-05 23.3 0.0 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 OAG35276.1 - 0.0001 21.2 0.0 0.0028 16.4 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 OAG35276.1 - 0.00054 20.5 0.0 0.0049 17.4 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 OAG35276.1 - 0.0008 18.8 0.0 0.49 9.6 0.0 2.8 4 0 0 4 4 4 2 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.21 OAG35276.1 - 0.0012 18.2 0.0 0.0025 17.2 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 OAG35276.1 - 0.0064 15.6 0.2 0.0098 15.0 0.2 1.5 1 1 0 1 1 1 1 Glucose inhibited division protein A AveC_like PF17198.4 OAG35277.1 - 2e-27 96.2 4.8 2e-27 96.2 4.8 1.6 2 0 0 2 2 2 1 Spirocyclase AveC-like DctQ PF04290.12 OAG35277.1 - 0.4 10.6 7.4 1.5 8.7 0.0 3.5 4 0 0 4 4 4 0 Tripartite ATP-independent periplasmic transporters, DctQ component DapB_N PF01113.20 OAG35278.1 - 2.1e-07 31.1 0.0 3.5e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Fungal_trans PF04082.18 OAG35279.1 - 2.3e-07 30.1 0.0 3.9e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Methyltransf_11 PF08241.12 OAG35280.1 - 9.7e-16 58.2 0.0 2.3e-15 57.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG35280.1 - 2.4e-15 57.0 0.0 6.6e-15 55.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG35280.1 - 4.1e-11 43.5 0.0 1.1e-10 42.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG35280.1 - 4.2e-08 33.1 0.0 9.5e-08 32.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAG35280.1 - 2.4e-07 30.8 0.0 7.9e-07 29.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Fungal_trans_2 PF11951.8 OAG35280.1 - 4e-05 22.6 0.2 7e-05 21.8 0.2 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Ubie_methyltran PF01209.18 OAG35280.1 - 0.0044 16.4 0.0 0.0083 15.5 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 OAG35280.1 - 0.087 12.1 0.0 0.31 10.3 0.0 1.8 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase Thioredoxin PF00085.20 OAG35281.1 - 1.6e-61 204.7 0.6 1.3e-29 102.3 0.0 4.2 4 0 0 4 4 4 3 Thioredoxin Thioredoxin_6 PF13848.6 OAG35281.1 - 9e-49 165.9 0.0 6.9e-36 123.9 0.0 3.3 2 1 1 3 3 3 3 Thioredoxin-like domain Calsequestrin PF01216.17 OAG35281.1 - 4.5e-08 32.5 0.3 1e-07 31.4 0.1 1.6 1 1 1 2 2 2 1 Calsequestrin Thioredoxin_8 PF13905.6 OAG35281.1 - 8.8e-07 29.2 0.0 0.13 12.6 0.0 4.2 4 1 1 5 5 5 2 Thioredoxin-like Thioredoxin_7 PF13899.6 OAG35281.1 - 8.8e-07 29.0 0.0 0.038 14.2 0.0 3.3 3 0 0 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.21 OAG35281.1 - 1.4e-06 28.3 0.7 0.054 13.4 0.0 3.5 4 0 0 4 4 4 2 AhpC/TSA family Thioredoxin_2 PF13098.6 OAG35281.1 - 2.5e-06 27.9 0.2 0.022 15.2 0.0 2.9 2 1 0 2 2 2 2 Thioredoxin-like domain Redoxin PF08534.10 OAG35281.1 - 1.1e-05 25.2 3.8 0.21 11.3 0.0 3.9 4 0 0 4 4 4 3 Redoxin OST3_OST6 PF04756.13 OAG35281.1 - 0.00059 19.3 0.0 1.4 8.2 0.0 3.2 3 1 0 4 4 4 2 OST3 / OST6 family, transporter family Thioredoxin_4 PF13462.6 OAG35281.1 - 0.042 14.0 2.8 0.92 9.6 0.0 3.3 3 0 0 3 3 3 0 Thioredoxin Thioredoxin_3 PF13192.6 OAG35281.1 - 0.15 12.1 0.5 2 8.5 0.1 2.8 3 0 0 3 3 3 0 Thioredoxin domain ATG22 PF11700.8 OAG35282.1 - 1.5e-207 689.9 7.8 1.8e-207 689.7 7.8 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 OAG35282.1 - 3.5e-06 26.2 21.1 3.5e-06 26.2 21.1 3.2 2 1 1 3 3 3 3 Major Facilitator Superfamily Med14 PF08638.11 OAG35283.1 - 2.3e-56 190.3 0.0 5.3e-56 189.1 0.0 1.7 1 0 0 1 1 1 1 Mediator complex subunit MED14 UDG PF03167.19 OAG35284.1 - 5.8e-22 78.4 0.0 1.2e-21 77.3 0.0 1.4 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Zn_clus PF00172.18 OAG35285.1 - 2.7e-10 40.2 8.8 5.4e-10 39.2 8.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_20 PF00728.22 OAG35286.1 - 6.5e-102 341.5 0.6 1e-101 340.9 0.6 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 OAG35286.1 - 3.5e-24 86.0 0.4 1.2e-23 84.3 0.1 2.0 2 0 0 2 2 2 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 OAG35286.1 - 0.00051 20.8 0.1 0.0011 19.7 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 MukF_C PF17193.4 OAG35286.1 - 0.14 12.3 0.0 0.25 11.5 0.0 1.3 1 0 0 1 1 1 0 MukF C-terminal domain MmgE_PrpD PF03972.14 OAG35287.1 - 5.3e-114 381.2 0.0 6e-114 381.0 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family Aminotran_1_2 PF00155.21 OAG35288.1 - 7.9e-37 127.3 0.0 3.6e-36 125.1 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_3 PF00202.21 OAG35288.1 - 0.003 16.3 0.0 0.0047 15.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-III DUF1479 PF07350.12 OAG35289.1 - 7.3e-43 146.9 0.0 8.3e-43 146.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) PhyH PF05721.13 OAG35289.1 - 0.094 13.0 0.1 0.19 12.0 0.1 1.5 1 0 0 1 1 1 0 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 OAG35290.1 - 5.9e-76 255.9 0.2 7.3e-76 255.6 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) Fungal_trans PF04082.18 OAG35291.1 - 4.3e-21 75.1 0.2 4.3e-21 75.1 0.2 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Amidase PF01425.21 OAG35292.1 - 1.3e-86 291.4 0.0 2.3e-86 290.5 0.0 1.4 1 1 0 1 1 1 1 Amidase Sugar_tr PF00083.24 OAG35293.1 - 6.6e-75 252.7 20.0 7.8e-75 252.5 20.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG35293.1 - 4.2e-18 65.4 54.5 1.8e-15 56.7 28.9 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2070 PF09843.9 OAG35293.1 - 0.042 12.2 2.5 0.07 11.4 2.5 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Cyclase PF04199.13 OAG35294.1 - 1.8e-12 47.6 0.0 2.4e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase Cupin_3 PF05899.12 OAG35294.1 - 0.052 13.2 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF861) ABC_membrane PF00664.23 OAG35297.1 - 1.1e-60 205.7 39.6 1.4e-37 129.8 18.2 3.2 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 OAG35297.1 - 2.5e-48 164.1 0.0 2.7e-27 96.0 0.0 3.1 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.19 OAG35297.1 - 3.2e-07 30.0 0.4 0.25 10.7 0.1 3.9 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 OAG35297.1 - 4.2e-06 26.8 0.1 0.021 14.9 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_21 PF13304.6 OAG35297.1 - 4e-05 23.6 1.6 0.29 10.9 0.0 3.5 2 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 OAG35297.1 - 4.5e-05 23.1 0.6 0.3 10.9 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 OAG35297.1 - 7.6e-05 22.7 0.3 0.46 10.4 0.1 3.2 3 0 0 3 3 3 2 RsgA GTPase AAA_16 PF13191.6 OAG35297.1 - 8.3e-05 23.0 0.3 0.27 11.6 0.0 3.3 2 1 1 3 3 2 2 AAA ATPase domain Zeta_toxin PF06414.12 OAG35297.1 - 0.00031 20.1 0.0 0.021 14.1 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_22 PF13401.6 OAG35297.1 - 0.00077 19.8 1.2 2.8 8.2 0.1 3.2 2 1 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 OAG35297.1 - 0.0033 17.2 0.1 0.73 9.5 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_15 PF13175.6 OAG35297.1 - 0.0045 16.8 2.4 2.5 7.7 0.0 3.2 3 1 0 3 3 3 2 AAA ATPase domain AAA_30 PF13604.6 OAG35297.1 - 0.0088 15.8 3.7 1.3 8.7 0.1 3.2 3 0 0 3 3 3 1 AAA domain Ploopntkinase3 PF18751.1 OAG35297.1 - 0.009 15.9 0.0 4.4 7.2 0.0 3.0 3 0 0 3 3 2 1 P-loop Nucleotide Kinase3 NACHT PF05729.12 OAG35297.1 - 0.018 15.0 0.8 0.3 11.0 0.0 2.8 3 0 0 3 3 3 0 NACHT domain AAA_23 PF13476.6 OAG35297.1 - 0.021 15.3 0.8 0.19 12.2 0.1 3.9 3 1 1 4 4 2 0 AAA domain AAA_18 PF13238.6 OAG35297.1 - 0.028 15.0 0.0 3.8 8.1 0.0 2.9 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 OAG35297.1 - 0.033 14.2 6.2 0.59 10.2 0.1 3.3 3 0 0 3 3 3 0 Dynamin family SRP54 PF00448.22 OAG35297.1 - 0.037 13.6 0.3 0.43 10.2 0.1 2.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Roc PF08477.13 OAG35297.1 - 0.056 13.7 0.1 12 6.1 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 OAG35297.1 - 0.067 12.7 0.1 4.2 6.9 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region MeaB PF03308.16 OAG35297.1 - 0.073 12.0 0.3 8.4 5.3 0.1 2.4 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_28 PF13521.6 OAG35297.1 - 0.15 12.3 3.1 0.46 10.7 0.1 3.0 3 0 0 3 3 2 0 AAA domain cobW PF02492.19 OAG35297.1 - 0.24 11.0 1.0 1.5 8.3 0.2 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AP3D1 PF06375.11 OAG35297.1 - 0.44 10.8 12.6 0.32 11.2 4.3 2.6 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 Sec62 PF03839.16 OAG35297.1 - 0.6 9.6 3.3 18 4.7 0.1 2.8 2 0 0 2 2 2 0 Translocation protein Sec62 ATP_bind_1 PF03029.17 OAG35297.1 - 0.98 9.2 2.9 11 5.7 0.2 2.9 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein DUF87 PF01935.17 OAG35297.1 - 3.7 7.6 11.4 0.19 11.8 0.3 2.9 2 1 1 3 3 3 0 Helicase HerA, central domain Coilin_N PF15862.5 OAG35297.1 - 6.1 6.6 11.5 16 5.3 0.2 2.6 2 0 0 2 2 2 0 Coilin N-terminus adh_short PF00106.25 OAG35298.1 - 6.4e-44 149.8 0.0 8.5e-44 149.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG35298.1 - 8e-30 104.1 0.0 1e-29 103.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG35298.1 - 0.00025 21.0 0.1 0.00039 20.4 0.1 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 OAG35298.1 - 0.0017 18.3 0.0 0.0024 17.8 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAG35298.1 - 0.0048 16.4 0.0 0.02 14.4 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.17 OAG35298.1 - 0.03 14.9 0.1 0.41 11.2 0.0 2.3 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent NmrA PF05368.13 OAG35298.1 - 0.045 13.3 0.0 0.11 12.1 0.0 1.5 2 0 0 2 2 2 0 NmrA-like family Fer2_3 PF13085.6 OAG35299.1 - 9.6e-32 109.2 0.0 1.5e-31 108.6 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 OAG35299.1 - 1.8e-08 34.8 6.0 1.8e-08 34.8 6.0 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 OAG35299.1 - 9.8e-08 32.3 7.0 9.8e-08 32.3 7.0 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 OAG35299.1 - 4.9e-07 29.8 2.6 4.9e-07 29.8 2.6 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 OAG35299.1 - 0.00097 19.7 3.4 0.00097 19.7 3.4 2.4 2 2 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 OAG35299.1 - 0.011 15.6 0.4 0.011 15.6 0.4 2.1 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain Fer4_18 PF13746.6 OAG35299.1 - 0.079 13.2 2.5 0.91 9.7 0.1 2.8 3 0 0 3 3 3 0 4Fe-4S dicluster domain SF3a60_bindingd PF12108.8 OAG35299.1 - 0.19 11.6 2.2 0.25 11.3 0.4 2.0 2 0 0 2 2 2 0 Splicing factor SF3a60 binding domain Fer4_9 PF13187.6 OAG35299.1 - 2.6 8.3 12.2 28 5.0 5.2 2.9 2 1 2 4 4 4 0 4Fe-4S dicluster domain AIG2_2 PF13772.6 OAG35300.1 - 0.00017 21.9 0.0 0.00042 20.7 0.0 1.7 1 0 0 1 1 1 1 AIG2-like family GATase_6 PF13522.6 OAG35301.1 - 1.4e-09 38.2 0.2 2.7e-09 37.3 0.2 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 OAG35301.1 - 1e-07 31.2 0.2 6.5e-07 28.5 0.2 2.1 1 1 0 1 1 1 1 Glutamine amidotransferases class-II Glyco_hydro_47 PF01532.20 OAG35302.1 - 4.1e-168 560.0 2.1 5.2e-168 559.7 2.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 WBS_methylT PF12589.8 OAG35303.1 - 2.1e-13 50.8 4.3 3.4e-13 50.1 4.3 1.4 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.12 OAG35303.1 - 1.8e-12 47.8 0.0 3.4e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG35303.1 - 1.3e-11 45.1 0.0 3.3e-11 43.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG35303.1 - 1.1e-06 29.2 0.0 2.8e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAG35303.1 - 3e-05 23.9 0.0 4.5e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 OAG35303.1 - 0.00046 20.0 0.0 0.00077 19.3 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 OAG35303.1 - 0.0014 18.4 0.0 0.0021 17.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 OAG35303.1 - 0.0026 17.1 0.0 0.0056 16.0 0.0 1.4 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 OAG35303.1 - 0.0085 15.5 0.2 0.037 13.3 0.0 2.1 2 1 1 3 3 3 1 ubiE/COQ5 methyltransferase family AdoMet_MTase PF07757.13 OAG35303.1 - 0.0087 16.4 0.0 0.021 15.2 0.0 1.7 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase AA_permease_2 PF13520.6 OAG35304.1 - 8.9e-61 206.0 51.6 1.1e-60 205.7 51.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAG35304.1 - 1.6e-23 83.1 44.0 1.6e-23 83.1 44.0 1.9 1 1 1 2 2 2 1 Amino acid permease Phage_CII PF05269.11 OAG35304.1 - 0.0034 17.6 0.4 0.0095 16.1 0.0 2.0 2 0 0 2 2 2 1 Bacteriophage CII protein Erv26 PF04148.13 OAG35306.1 - 3.5e-88 294.8 0.0 4e-88 294.6 0.0 1.0 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 TENA_THI-4 PF03070.16 OAG35307.1 - 3.9e-08 33.4 0.1 1e-05 25.4 0.1 2.7 2 1 0 2 2 2 2 TENA/THI-4/PQQC family SURF2 PF05477.11 OAG35307.1 - 0.21 11.2 1.2 0.38 10.4 1.2 1.3 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) G_path_suppress PF15991.5 OAG35307.1 - 7.6 6.6 12.6 12 6.0 12.6 1.2 1 0 0 1 1 1 0 G-protein pathway suppressor adh_short PF00106.25 OAG35308.1 - 1.9e-45 154.7 0.0 2.6e-45 154.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG35308.1 - 5.8e-32 111.1 0.0 7.2e-32 110.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG35308.1 - 4e-06 26.8 0.0 8.1e-06 25.9 0.0 1.6 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 OAG35308.1 - 0.00085 19.3 0.0 0.0017 18.3 0.0 1.7 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAG35308.1 - 0.046 13.2 0.0 0.073 12.5 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 OAG35308.1 - 0.053 12.6 0.0 0.097 11.8 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain Csm1_N PF18504.1 OAG35309.1 - 0.13 12.6 3.5 0.19 12.1 3.5 1.2 1 0 0 1 1 1 0 Csm1 N-terminal domain DUF3450 PF11932.8 OAG35309.1 - 0.21 10.8 5.1 0.3 10.4 5.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) MOSC PF03473.17 OAG35311.1 - 1.7e-33 115.4 0.1 4.3e-33 114.1 0.1 1.7 1 0 0 1 1 1 1 MOSC domain Aminotran_5 PF00266.19 OAG35311.1 - 2.9e-24 85.7 0.0 4.1e-24 85.2 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V MOSC_N PF03476.16 OAG35311.1 - 1.1e-19 70.5 0.0 2.3e-19 69.5 0.0 1.6 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain Sugar_tr PF00083.24 OAG35312.1 - 5.3e-78 262.9 24.3 6.1e-78 262.7 24.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG35312.1 - 1.4e-22 80.1 31.8 1.2e-18 67.1 21.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 OAG35312.1 - 5.6e-05 21.8 1.6 0.0001 20.9 1.6 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.6 OAG35312.1 - 8e-05 21.4 15.9 0.00011 20.9 0.8 2.3 2 0 0 2 2 2 2 MFS/sugar transport protein DUF4293 PF14126.6 OAG35312.1 - 0.082 13.1 3.7 0.25 11.6 3.7 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4293) MARVEL PF01284.23 OAG35313.1 - 9e-06 25.8 14.7 1.2e-05 25.3 14.7 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF3367 PF11847.8 OAG35313.1 - 0.064 11.1 0.4 0.081 10.8 0.4 1.1 1 0 0 1 1 1 0 Alpha-(1->3)-arabinofuranosyltransferase PLDc_N PF13396.6 OAG35313.1 - 0.64 10.0 7.2 0.44 10.5 0.6 3.6 3 0 0 3 3 3 0 Phospholipase_D-nuclease N-terminal UNC-50 PF05216.13 OAG35313.1 - 1.2 8.7 8.0 0.088 12.4 3.0 1.6 2 0 0 2 2 2 0 UNC-50 family Peptidase_S49 PF01343.18 OAG35314.1 - 0.04 13.9 0.0 0.071 13.1 0.0 1.4 1 0 0 1 1 1 0 Peptidase family S49 ADH_N PF08240.12 OAG35315.1 - 1.7e-23 82.6 2.7 1.7e-23 82.6 2.7 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG35315.1 - 2.3e-17 63.2 1.3 3.6e-17 62.6 1.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAG35315.1 - 6.7e-06 27.2 0.1 1.1e-05 26.5 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase RuvC PF02075.17 OAG35316.1 - 0.13 12.1 0.2 0.26 11.2 0.2 1.4 1 0 0 1 1 1 0 Crossover junction endodeoxyribonuclease RuvC HrpJ PF07201.11 OAG35318.1 - 0.031 14.6 0.4 0.075 13.3 0.2 1.6 1 1 1 2 2 2 0 HrpJ-like domain TPR_11 PF13414.6 OAG35318.1 - 0.039 13.6 0.6 30 4.4 0.1 3.3 3 0 0 3 3 3 0 TPR repeat TPR_14 PF13428.6 OAG35318.1 - 0.21 12.5 0.9 15 6.7 0.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF2854 PF11016.8 OAG35318.1 - 0.46 10.4 1.7 0.53 10.2 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2854) NatB_MDM20 PF09797.9 OAG35319.1 - 6.1e-49 167.0 0.3 1.3e-48 165.9 0.0 1.7 2 0 0 2 2 2 1 N-acetyltransferase B complex (NatB) non catalytic subunit Proteasome PF00227.26 OAG35320.1 - 3.8e-38 130.9 0.0 4.2e-38 130.7 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit H_lectin PF09458.10 OAG35320.1 - 0.064 13.5 0.1 0.12 12.6 0.1 1.4 1 0 0 1 1 1 0 H-type lectin domain TUG-UBL1 PF11470.8 OAG35321.1 - 4.7e-26 90.8 0.1 1.5e-25 89.2 0.0 1.9 2 0 0 2 2 2 1 TUG ubiquitin-like domain UBX PF00789.20 OAG35321.1 - 8.7e-06 25.9 0.0 3.6e-05 23.9 0.0 2.1 2 0 0 2 2 2 1 UBX domain RBD PF02196.15 OAG35321.1 - 0.012 15.7 0.0 0.19 11.8 0.0 2.5 2 0 0 2 2 2 0 Raf-like Ras-binding domain ATF7IP_BD PF16788.5 OAG35321.1 - 0.47 10.5 4.0 0.45 10.6 2.6 1.7 1 1 0 1 1 1 0 ATF-interacting protein binding domain Acetyltransf_3 PF13302.7 OAG35322.1 - 1.4e-20 74.4 0.0 2e-20 73.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 OAG35322.1 - 0.00088 19.0 0.6 1.2 8.8 0.1 2.8 3 0 0 3 3 3 2 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAG35322.1 - 0.013 15.4 0.1 4.4 7.3 0.0 2.4 2 0 0 2 2 2 0 FR47-like protein DNA_pol_E_B PF04042.16 OAG35323.1 - 2.8e-43 147.8 0.0 3.7e-43 147.4 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 OAG35323.1 - 7.5e-43 145.8 0.0 1.3e-42 145.0 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain 4HBT PF03061.22 OAG35325.1 - 4.5e-09 36.5 0.1 8.1e-09 35.7 0.1 1.4 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.6 OAG35325.1 - 0.0007 19.7 0.1 0.001 19.2 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4442) Lipocalin_5 PF13924.6 OAG35326.1 - 2.1e-24 86.0 0.0 2.4e-24 85.7 0.0 1.1 1 0 0 1 1 1 1 Lipocalin-like domain Fungal_trans PF04082.18 OAG35327.1 - 3e-15 56.0 0.7 5.5e-15 55.1 0.1 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain 7TM_GPCR_Sri PF10327.9 OAG35327.1 - 0.044 13.0 0.3 0.08 12.1 0.3 1.4 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Sri Leader_Trp PF08255.11 OAG35327.1 - 3.8 7.7 6.9 32 4.8 0.0 3.6 3 0 0 3 3 3 0 Trp-operon Leader Peptide SnoaL_2 PF12680.7 OAG35328.1 - 1.3e-05 25.8 0.5 1.7e-05 25.4 0.5 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 OAG35328.1 - 0.013 15.9 0.1 0.02 15.3 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4440) FAD_binding_3 PF01494.19 OAG35329.1 - 1.4e-53 182.4 0.1 8.2e-53 179.9 0.1 1.9 1 1 0 1 1 1 1 FAD binding domain FAA_hydrolase PF01557.18 OAG35330.1 - 1.1e-56 192.0 0.0 1.2e-56 191.9 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Glyoxalase PF00903.25 OAG35331.1 - 1.2e-11 44.8 0.1 2e-11 44.2 0.1 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 OAG35331.1 - 0.039 14.8 0.0 0.061 14.1 0.0 1.3 1 0 0 1 1 1 0 Glyoxalase-like domain DUF2315 PF10231.9 OAG35331.1 - 0.11 12.6 0.1 0.21 11.7 0.1 1.4 1 0 0 1 1 1 0 Apoptogenic protein 1 Glyoxalase PF00903.25 OAG35332.1 - 0.088 13.0 0.3 5.6 7.2 0.1 2.7 2 1 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily MFS_1 PF07690.16 OAG35333.1 - 2.3e-22 79.4 38.0 2.3e-22 79.4 38.0 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily LIM PF00412.22 OAG35334.1 - 3.6e-24 84.7 23.5 1.4e-09 38.0 5.1 3.9 4 0 0 4 4 4 3 LIM domain Zn_ribbon_recom PF13408.6 OAG35334.1 - 0.0072 16.8 2.8 0.0072 16.8 2.8 2.6 3 1 0 3 3 3 1 Recombinase zinc beta ribbon domain DUF2321 PF10083.9 OAG35334.1 - 0.0076 15.9 1.4 0.0076 15.9 1.4 3.3 2 1 1 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2321) Paired_CXXCH_1 PF09699.10 OAG35334.1 - 0.48 10.2 12.0 0.061 13.1 0.8 3.4 3 0 0 3 3 3 0 Doubled CXXCH motif (Paired_CXXCH_1) SNF2_N PF00176.23 OAG35335.1 - 2.4e-55 187.7 0.0 4.6e-55 186.7 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.24 OAG35335.1 - 2e-23 82.0 4.2 1.6e-14 53.5 0.4 3.0 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain DUF4208 PF13907.6 OAG35335.1 - 2.1e-20 72.9 1.1 1.5e-19 70.2 0.0 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4208) Helicase_C PF00271.31 OAG35335.1 - 1.3e-17 64.2 0.0 3.4e-17 62.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Cdh1_DBD_1 PF18196.1 OAG35335.1 - 6.5e-05 23.2 2.6 0.0004 20.7 0.3 4.8 4 1 1 5 5 5 2 Chromodomain helicase DNA-binding domain 1 ResIII PF04851.15 OAG35335.1 - 7.2e-05 22.8 0.0 0.0038 17.3 0.0 2.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SLIDE PF09111.10 OAG35335.1 - 0.048 13.7 4.8 0.11 12.5 0.0 3.7 4 0 0 4 4 4 0 SLIDE CHDCT2 PF08074.11 OAG35335.1 - 0.17 12.1 0.0 0.17 12.1 0.0 3.2 4 0 0 4 4 4 0 CHDCT2 (NUC038) domain ABC_tran PF00005.27 OAG35336.1 - 1.1e-33 116.6 0.0 1.2e-15 58.2 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 OAG35336.1 - 5.8e-12 45.5 1.8 0.0033 16.9 0.0 3.9 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 OAG35336.1 - 8.4e-10 38.9 7.0 0.068 13.0 0.0 4.3 2 2 2 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system RLI PF04068.15 OAG35336.1 - 5.2e-07 29.4 1.6 5.2e-07 29.4 1.6 2.1 2 0 0 2 2 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Rad17 PF03215.15 OAG35336.1 - 4.1e-06 26.9 0.2 0.022 14.7 0.0 2.6 2 1 1 3 3 3 2 Rad17 P-loop domain AAA_15 PF13175.6 OAG35336.1 - 2.2e-05 24.4 0.2 0.22 11.2 0.0 3.1 3 1 0 4 4 3 2 AAA ATPase domain Fer4 PF00037.27 OAG35336.1 - 3.8e-05 23.3 3.0 3.8e-05 23.3 3.0 2.2 2 0 0 2 2 2 1 4Fe-4S binding domain AAA PF00004.29 OAG35336.1 - 7e-05 23.3 0.1 0.1 13.0 0.1 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OAG35336.1 - 0.00012 22.4 0.0 0.027 14.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 OAG35336.1 - 0.00013 21.9 0.0 0.45 10.4 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_13 PF13166.6 OAG35336.1 - 0.00025 19.8 0.0 0.00063 18.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OAG35336.1 - 0.00028 21.3 0.0 0.64 10.4 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 OAG35336.1 - 0.00054 19.7 0.4 0.59 9.9 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_24 PF13479.6 OAG35336.1 - 0.0012 18.6 1.7 0.095 12.4 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 OAG35336.1 - 0.0012 18.4 0.7 0.018 14.5 0.2 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_18 PF13238.6 OAG35336.1 - 0.0019 18.8 0.0 3.1 8.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain Fer4_21 PF14697.6 OAG35336.1 - 0.0023 18.0 9.0 0.0046 17.0 9.0 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain RNA_helicase PF00910.22 OAG35336.1 - 0.0028 18.0 0.1 1.2 9.6 0.0 2.6 2 0 0 2 2 2 1 RNA helicase SRP54 PF00448.22 OAG35336.1 - 0.005 16.5 3.5 0.084 12.5 0.1 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_28 PF13521.6 OAG35336.1 - 0.0083 16.4 0.0 1.9 8.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 OAG35336.1 - 0.0089 16.2 0.1 1.7 8.8 0.1 2.5 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 OAG35336.1 - 0.013 14.7 0.0 1.3 8.1 0.0 2.4 3 0 0 3 3 2 0 NB-ARC domain TsaE PF02367.17 OAG35336.1 - 0.015 15.3 0.1 0.2 11.7 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Fer4_9 PF13187.6 OAG35336.1 - 0.024 14.8 9.3 0.05 13.8 9.3 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_7 PF12838.7 OAG35336.1 - 0.03 14.9 8.7 0.066 13.8 8.7 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain Thymidylate_kin PF02223.17 OAG35336.1 - 0.037 13.7 0.4 14 5.3 0.0 3.0 3 0 0 3 3 3 0 Thymidylate kinase AAA_23 PF13476.6 OAG35336.1 - 0.038 14.5 2.6 1.4 9.3 0.3 2.5 2 0 0 2 2 2 0 AAA domain Fer4_16 PF13484.6 OAG35336.1 - 0.038 14.9 5.0 0.077 13.9 0.3 2.7 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain NACHT PF05729.12 OAG35336.1 - 0.043 13.7 3.1 1.8 8.5 0.1 2.8 3 0 0 3 3 2 0 NACHT domain ATPase PF06745.13 OAG35336.1 - 0.043 13.2 0.2 0.094 12.0 0.2 1.5 1 0 0 1 1 1 0 KaiC AAA_30 PF13604.6 OAG35336.1 - 0.066 12.9 0.5 4.3 7.0 0.1 2.4 2 0 0 2 2 2 0 AAA domain DLIC PF05783.11 OAG35336.1 - 0.072 11.9 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Fer4_10 PF13237.6 OAG35336.1 - 0.08 13.1 12.3 0.038 14.1 1.8 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain VirE PF05272.11 OAG35336.1 - 0.087 12.5 0.0 6 6.5 0.0 2.4 2 0 0 2 2 2 0 Virulence-associated protein E Lactococcin PF04369.13 OAG35336.1 - 0.12 12.6 0.0 1.5 9.0 0.0 2.3 2 0 0 2 2 2 0 Lactococcin-like family PduV-EutP PF10662.9 OAG35336.1 - 0.12 12.1 0.1 0.12 12.1 0.1 2.2 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation DnaB_C PF03796.15 OAG35336.1 - 0.12 11.6 0.0 0.29 10.4 0.0 1.6 2 0 0 2 2 1 0 DnaB-like helicase C terminal domain TniB PF05621.11 OAG35336.1 - 0.15 11.4 0.1 0.92 8.9 0.0 2.1 2 0 0 2 2 2 0 Bacterial TniB protein AAA_14 PF13173.6 OAG35336.1 - 0.16 12.0 0.1 12 5.9 0.1 2.9 2 1 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 OAG35336.1 - 0.16 12.0 0.4 28 4.8 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase Fer4_6 PF12837.7 OAG35336.1 - 1.1 9.4 9.9 0.074 13.1 2.9 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain NTPase_1 PF03266.15 OAG35336.1 - 1.4 8.8 3.3 19 5.1 0.2 2.9 3 0 0 3 3 3 0 NTPase Fer4_17 PF13534.6 OAG35336.1 - 3.8 8.1 9.7 0.24 12.0 1.0 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_2 PF12797.7 OAG35336.1 - 4 7.7 6.8 0.81 9.9 1.2 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_8 PF13183.6 OAG35336.1 - 5.1 7.6 10.5 1.4 9.4 2.2 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain Stb3 PF10330.9 OAG35337.1 - 1.4e-39 134.0 0.0 2.6e-39 133.2 0.0 1.4 1 0 0 1 1 1 1 Putative Sin3 binding protein Kelch_6 PF13964.6 OAG35338.1 - 2.7e-05 24.3 8.5 0.011 16.0 0.1 4.2 4 0 0 4 4 4 2 Kelch motif Kelch_5 PF13854.6 OAG35338.1 - 0.0048 16.8 5.5 0.057 13.4 0.3 3.4 3 0 0 3 3 3 1 Kelch motif Kelch_3 PF13415.6 OAG35338.1 - 0.097 13.0 0.3 0.097 13.0 0.3 3.7 4 0 0 4 4 4 0 Galactose oxidase, central domain TMEM154 PF15102.6 OAG35338.1 - 0.2 11.6 0.0 1.7 8.5 0.0 2.5 2 0 0 2 2 2 0 TMEM154 protein family DUF202 PF02656.15 OAG35338.1 - 0.48 10.9 1.8 0.99 9.9 1.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF202) Kelch_4 PF13418.6 OAG35338.1 - 5.4 7.1 7.6 9.2 6.4 0.1 3.7 4 0 0 4 4 4 0 Galactose oxidase, central domain TPR_14 PF13428.6 OAG35339.1 - 5.7e-23 79.7 33.3 0.0029 18.3 0.2 12.5 5 2 9 14 14 14 6 Tetratricopeptide repeat HAT PF02184.16 OAG35339.1 - 1.3e-21 76.2 90.5 4.3e-15 55.4 4.1 14.1 15 1 0 15 15 15 4 HAT (Half-A-TPR) repeat TPR_19 PF14559.6 OAG35339.1 - 3.7e-21 75.4 0.1 4.7e-05 23.8 0.0 7.5 7 0 0 7 7 7 4 Tetratricopeptide repeat Suf PF05843.14 OAG35339.1 - 7.3e-15 55.7 28.8 0.00031 20.8 0.4 6.5 2 1 4 6 6 6 4 Suppressor of forked protein (Suf) TPR_17 PF13431.6 OAG35339.1 - 1.8e-09 37.3 5.0 0.031 14.6 0.0 7.5 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_2 PF07719.17 OAG35339.1 - 9.6e-09 34.7 26.0 0.89 9.8 0.0 10.0 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_8 PF13181.6 OAG35339.1 - 1.5e-07 31.1 15.3 5.5 7.5 0.0 9.8 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_6 PF13174.6 OAG35339.1 - 9.8e-06 25.9 22.0 2.9 8.7 0.1 8.5 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_15 PF13429.6 OAG35339.1 - 2.8e-05 23.5 19.2 0.061 12.5 4.2 6.0 1 1 4 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.6 OAG35339.1 - 5.9e-05 23.6 21.2 2.3 8.9 0.0 8.2 9 1 1 10 10 9 1 Tetratricopeptide repeat TPR_7 PF13176.6 OAG35339.1 - 0.075 13.1 14.1 15 5.9 0.0 6.8 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.6 OAG35339.1 - 0.2 12.0 21.0 7 7.0 0.0 8.3 10 0 0 10 10 10 0 Tetratricopeptide repeat U3_assoc_6 PF08640.11 OAG35339.1 - 0.36 10.9 37.0 0.07 13.2 2.9 8.6 5 3 4 9 9 9 0 U3 small nucleolar RNA-associated protein 6 Fis1_TPR_C PF14853.6 OAG35339.1 - 0.4 10.8 14.7 17 5.6 0.9 5.9 7 0 0 7 7 7 0 Fis1 C-terminal tetratricopeptide repeat TPR_1 PF00515.28 OAG35339.1 - 1.8 8.5 13.5 22 5.1 0.0 6.1 8 0 0 8 8 8 0 Tetratricopeptide repeat Nop PF01798.18 OAG35340.1 - 7.4e-70 235.0 0.0 1.2e-69 234.3 0.0 1.3 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 OAG35340.1 - 2.2e-47 160.9 1.6 2.2e-47 160.9 1.6 1.8 2 0 0 2 2 2 1 Prp31 C terminal domain YqgC PF17430.2 OAG35340.1 - 0.083 13.0 0.0 2.5 8.2 0.0 2.6 2 0 0 2 2 2 0 Uncharacterized YqgC-like PTS_2-RNA PF01885.16 OAG35341.1 - 9e-60 201.8 0.0 1.1e-58 198.2 0.0 2.0 1 1 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family YL1 PF05764.13 OAG35341.1 - 0.0036 17.5 4.0 0.0067 16.6 4.0 1.5 1 0 0 1 1 1 1 YL1 nuclear protein CDC45 PF02724.14 OAG35341.1 - 0.022 13.1 4.5 0.033 12.5 4.5 1.4 1 0 0 1 1 1 0 CDC45-like protein PBP1_TM PF14812.6 OAG35341.1 - 0.35 11.2 8.9 1.1 9.6 8.9 1.9 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RP-C_C PF11800.8 OAG35341.1 - 0.39 10.8 3.3 0.31 11.1 0.5 2.1 2 0 0 2 2 2 0 Replication protein C C-terminal region Nop14 PF04147.12 OAG35341.1 - 0.42 8.8 8.1 0.7 8.0 8.1 1.2 1 0 0 1 1 1 0 Nop14-like family Apt1 PF10351.9 OAG35341.1 - 0.97 8.2 5.2 3.5 6.4 5.2 1.8 2 0 0 2 2 2 0 Golgi-body localisation protein domain DNA_pol_phi PF04931.13 OAG35341.1 - 3.3 5.7 9.8 4.9 5.1 9.8 1.2 1 0 0 1 1 1 0 DNA polymerase phi SKG6 PF08693.10 OAG35342.1 - 2.7e-10 39.5 2.0 6.5e-10 38.2 2.0 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain TMEM154 PF15102.6 OAG35342.1 - 6.9e-05 22.8 0.0 6.9e-05 22.8 0.0 3.1 1 1 1 2 2 2 1 TMEM154 protein family DUF4448 PF14610.6 OAG35342.1 - 0.00024 21.0 0.6 0.001 18.9 0.6 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4448) VSP PF03302.13 OAG35342.1 - 0.048 12.5 5.9 0.086 11.7 5.8 1.5 1 1 0 1 1 1 0 Giardia variant-specific surface protein EphA2_TM PF14575.6 OAG35342.1 - 0.085 13.7 0.0 0.17 12.8 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF2681 PF10883.8 OAG35342.1 - 0.15 12.5 0.1 0.25 11.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) SKG6 PF08693.10 OAG35343.1 - 0.0034 16.7 0.1 0.0064 15.9 0.1 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Pyr_redox_3 PF13738.6 OAG35344.1 - 3.4e-13 49.5 0.0 4.3e-12 45.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 OAG35344.1 - 2.9e-11 42.5 0.0 5.4e-09 35.0 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 OAG35344.1 - 4.3e-10 39.3 0.0 6.8e-09 35.4 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG35344.1 - 1.4e-09 37.6 0.0 2.5e-07 30.2 0.0 2.4 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 OAG35344.1 - 2.5e-05 24.4 0.0 7.3e-05 22.9 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 OAG35344.1 - 0.0023 17.9 0.1 0.15 12.1 0.1 3.0 2 1 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.17 OAG35344.1 - 0.069 12.4 0.0 0.15 11.3 0.0 1.5 1 0 0 1 1 1 0 Thi4 family DAO PF01266.24 OAG35344.1 - 0.12 11.9 0.0 2.8 7.4 0.0 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 OAG35344.1 - 0.13 11.3 0.0 0.27 10.2 0.0 1.5 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox PF00070.27 OAG35344.1 - 0.17 12.4 0.0 39 4.9 0.0 3.1 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.16 OAG35345.1 - 9.8e-44 149.7 34.8 9.8e-44 149.7 34.8 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG35345.1 - 9.5e-16 57.7 8.2 9.5e-16 57.7 8.2 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 OAG35345.1 - 0.005 15.2 5.8 0.039 12.2 5.5 2.2 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family ArsP_1 PF03773.13 OAG35345.1 - 0.021 14.0 8.1 0.1 11.7 8.0 2.0 1 1 0 1 1 1 0 Predicted permease ApbA_C PF08546.11 OAG35346.1 - 1.5e-30 105.9 0.0 2.6e-30 105.2 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 OAG35346.1 - 6.4e-27 94.1 0.2 8.7e-27 93.6 0.2 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA AA_permease PF00324.21 OAG35347.1 - 1.5e-104 350.3 33.8 1.8e-104 350.0 33.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAG35347.1 - 4.4e-35 121.3 37.4 5.3e-35 121.1 37.4 1.0 1 0 0 1 1 1 1 Amino acid permease Cu_amine_oxid PF01179.20 OAG35348.1 - 8.3e-153 509.1 0.0 1e-152 508.9 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 OAG35348.1 - 0.0018 18.7 0.0 0.01 16.2 0.0 2.1 2 0 0 2 2 2 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 OAG35348.1 - 0.1 12.8 0.1 0.23 11.7 0.1 1.5 1 0 0 1 1 1 0 Copper amine oxidase, N2 domain FMN_dh PF01070.18 OAG35349.1 - 2e-109 365.8 0.0 3.5e-109 365.0 0.0 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Fungal_trans PF04082.18 OAG35349.1 - 1.3e-20 73.6 0.0 2.1e-20 72.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain IMPDH PF00478.25 OAG35349.1 - 1.6e-07 30.7 0.0 3e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 OAG35349.1 - 0.00011 21.5 0.2 0.00027 20.2 0.1 1.6 1 1 1 2 2 2 1 Conserved region in glutamate synthase His_biosynth PF00977.21 OAG35349.1 - 0.086 12.3 0.1 2.8 7.3 0.1 2.2 1 1 1 2 2 2 0 Histidine biosynthesis protein F-box-like PF12937.7 OAG35351.1 - 4.1e-08 33.0 0.1 2.4e-07 30.5 0.0 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 OAG35351.1 - 9e-05 22.2 0.0 0.00034 20.4 0.0 2.1 1 0 0 1 1 1 1 F-box domain Sel1 PF08238.12 OAG35352.1 - 1e-12 48.2 0.7 8.2e-05 23.1 0.0 4.3 4 1 0 4 4 4 3 Sel1 repeat FYRN PF05964.14 OAG35352.1 - 0.14 12.0 0.1 0.33 10.8 0.1 1.6 1 0 0 1 1 1 0 F/Y-rich N-terminus bZIP_Maf PF03131.17 OAG35353.1 - 7.2e-06 26.4 11.1 2.5e-05 24.7 11.1 1.9 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_1 PF00170.21 OAG35353.1 - 2.4e-05 24.3 13.8 2.4e-05 24.3 13.8 2.4 1 1 2 3 3 3 1 bZIP transcription factor bZIP_2 PF07716.15 OAG35353.1 - 0.0024 17.9 12.3 0.0024 17.9 12.3 3.3 2 1 1 3 3 3 1 Basic region leucine zipper DUF1223 PF06764.11 OAG35354.1 - 3.5e-49 167.6 0.0 4.1e-49 167.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1223) PLAC8 PF04749.17 OAG35356.1 - 2e-23 83.2 13.4 2.5e-23 82.9 13.4 1.1 1 0 0 1 1 1 1 PLAC8 family Vps55 PF04133.14 OAG35356.1 - 0.074 13.0 0.1 0.1 12.6 0.1 1.1 1 0 0 1 1 1 0 Vacuolar protein sorting 55 Lactamase_B PF00753.27 OAG35357.1 - 1.7e-08 34.7 2.5 3.6e-07 30.4 2.5 2.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OAG35357.1 - 0.028 13.9 0.0 0.062 12.8 0.0 1.5 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Sox17_18_mid PF12067.8 OAG35357.1 - 0.14 12.3 4.1 0.33 11.0 4.1 1.6 1 0 0 1 1 1 0 Sox 17/18 central domain Lipocalin_5 PF13924.6 OAG35358.1 - 5e-19 68.5 0.0 5.7e-19 68.3 0.0 1.0 1 0 0 1 1 1 1 Lipocalin-like domain Aldedh PF00171.22 OAG35360.1 - 2.4e-152 507.7 0.1 2.9e-152 507.4 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 OAG35360.1 - 0.036 13.5 0.0 0.074 12.5 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1487) Halo_GVPC PF05465.13 OAG35360.1 - 0.079 13.2 0.7 0.23 11.7 0.7 1.8 1 0 0 1 1 1 0 Halobacterial gas vesicle protein C (GVPC) repeat FAD_binding_2 PF00890.24 OAG35361.1 - 3.6e-35 121.8 0.8 3.6e-34 118.6 0.8 2.0 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 OAG35361.1 - 4e-08 33.0 1.4 1.1e-06 28.3 1.4 2.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG35361.1 - 1.6e-06 27.5 0.4 0.087 12.0 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAG35361.1 - 1.9e-06 27.7 2.3 1.9e-06 27.7 2.3 2.4 3 1 0 3 3 3 1 FAD dependent oxidoreductase HI0933_like PF03486.14 OAG35361.1 - 8.2e-05 21.5 5.1 0.033 12.9 0.2 3.2 3 0 0 3 3 3 2 HI0933-like protein GMC_oxred_N PF00732.19 OAG35361.1 - 0.0035 16.8 0.0 0.0085 15.5 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase GIDA PF01134.22 OAG35361.1 - 0.0078 15.3 0.4 0.0078 15.3 0.4 2.7 3 0 0 3 3 3 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 OAG35361.1 - 0.015 14.6 0.2 0.29 10.3 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 OAG35361.1 - 0.019 14.2 0.0 0.038 13.2 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain NAD_binding_8 PF13450.6 OAG35361.1 - 0.022 15.0 0.3 0.1 12.8 0.3 2.2 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 OAG35361.1 - 0.053 14.1 0.3 18 6.0 0.0 3.1 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 OAG35361.1 - 0.068 12.5 0.0 0.15 11.3 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain PG_binding_2 PF08823.11 OAG35361.1 - 0.076 13.3 0.2 0.15 12.4 0.2 1.4 1 0 0 1 1 1 0 Putative peptidoglycan binding domain DUF3150 PF11348.8 OAG35361.1 - 0.23 10.7 0.0 0.43 9.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3150) adh_short_C2 PF13561.6 OAG35362.1 - 1.5e-57 194.8 0.1 1.9e-57 194.5 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG35362.1 - 1.1e-47 162.0 0.3 1.5e-47 161.6 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG35362.1 - 5.3e-11 42.8 0.1 6.6e-11 42.4 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG35362.1 - 0.037 13.5 0.0 0.048 13.1 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Oxysterol_BP PF01237.18 OAG35363.1 - 1.6e-57 195.1 0.4 3.7e-51 174.1 0.0 2.0 1 1 1 2 2 2 2 Oxysterol-binding protein DnaT PF17948.1 OAG35363.1 - 0.13 12.0 1.2 0.39 10.4 0.0 2.5 3 0 0 3 3 3 0 DnaT DNA-binding domain MOSC PF03473.17 OAG35364.1 - 3.7e-24 85.2 0.0 8.5e-24 84.0 0.0 1.6 2 0 0 2 2 2 1 MOSC domain MOSC_N PF03476.16 OAG35364.1 - 8.4e-18 64.4 0.0 1.4e-17 63.7 0.0 1.4 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain Cuticle_1 PF08140.11 OAG35364.1 - 0.048 13.7 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 Crustacean cuticle protein repeat Zn_clus PF00172.18 OAG35365.1 - 1.2e-10 41.3 10.3 2.1e-10 40.5 10.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 OAG35365.1 - 1.8e-06 27.0 3.2 0.032 13.0 1.0 3.0 2 1 0 2 2 2 2 Fungal specific transcription factor domain Adap_comp_sub PF00928.21 OAG35367.1 - 1.4e-83 280.3 0.0 1.8e-83 280.0 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 OAG35367.1 - 1.5e-05 24.9 0.2 2.7e-05 24.1 0.2 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Myb_DNA-bind_6 PF13921.6 OAG35368.1 - 0.017 15.3 0.0 0.031 14.5 0.0 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain DUF1996 PF09362.10 OAG35369.1 - 4.6e-74 249.4 0.4 8e-74 248.6 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) WSC PF01822.19 OAG35369.1 - 1.6e-59 198.0 63.1 4.3e-16 58.9 12.8 4.5 4 0 0 4 4 4 4 WSC domain Ank_2 PF12796.7 OAG35370.1 - 9.5e-24 83.8 0.0 8e-13 48.8 0.0 2.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAG35370.1 - 1.9e-22 79.3 0.9 1.2e-09 38.5 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 OAG35370.1 - 8e-21 73.5 4.1 5.2e-06 26.7 0.1 5.4 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 OAG35370.1 - 2.2e-19 67.5 3.0 0.00017 21.8 0.0 5.8 6 0 0 6 6 4 4 Ankyrin repeat Ank_5 PF13857.6 OAG35370.1 - 7e-19 67.6 1.0 7.8e-09 35.6 0.1 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) CorA PF01544.18 OAG35370.1 - 6e-09 35.6 0.1 6e-09 35.6 0.1 2.7 3 0 0 3 3 3 1 CorA-like Mg2+ transporter protein NACHT PF05729.12 OAG35370.1 - 1.9e-06 27.9 0.0 4e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_14 PF13173.6 OAG35370.1 - 0.0094 16.0 0.1 0.18 11.8 0.0 3.0 2 1 1 3 3 3 1 AAA domain LMBR1 PF04791.16 OAG35370.1 - 0.011 14.7 0.0 0.97 8.3 0.0 2.2 2 0 0 2 2 2 0 LMBR1-like membrane protein AAA_16 PF13191.6 OAG35370.1 - 0.023 15.1 0.7 0.052 13.9 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain TniB PF05621.11 OAG35370.1 - 0.033 13.6 0.0 4.6 6.6 0.0 2.4 2 0 0 2 2 2 0 Bacterial TniB protein ATPase_2 PF01637.18 OAG35370.1 - 0.11 12.4 0.1 0.75 9.7 0.0 2.1 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Yip1 PF04893.17 OAG35370.1 - 3.3 7.4 8.4 0.19 11.4 1.3 2.2 2 0 0 2 2 2 0 Yip1 domain DUF2423 PF10338.9 OAG35372.1 - 8.7e-18 64.3 4.5 8.7e-18 64.3 4.5 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2423) PINIT PF14324.6 OAG35373.1 - 3.4e-31 108.6 0.1 6.1e-31 107.7 0.1 1.4 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.20 OAG35373.1 - 2.6e-20 71.9 1.0 4.7e-20 71.1 1.0 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger SAP PF02037.27 OAG35373.1 - 4.9e-06 26.2 0.5 1.1e-05 25.0 0.5 1.6 1 0 0 1 1 1 1 SAP domain zf-Nse PF11789.8 OAG35373.1 - 0.0011 18.7 0.2 0.0023 17.7 0.2 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.6 OAG35373.1 - 0.073 12.9 0.8 0.16 11.9 0.8 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-Sec23_Sec24 PF04810.15 OAG35373.1 - 0.12 12.5 1.8 0.27 11.3 1.8 1.6 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger Methyltransf_16 PF10294.9 OAG35374.1 - 8.2e-05 22.4 0.2 0.27 11.0 0.3 3.0 2 1 0 2 2 2 2 Lysine methyltransferase Methyltransf_31 PF13847.6 OAG35375.1 - 1.9e-16 60.2 0.0 1.5e-15 57.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG35375.1 - 1e-08 35.8 0.0 4.6e-08 33.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAG35375.1 - 3.7e-07 30.1 0.0 6.2e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG35375.1 - 4e-07 30.6 0.2 6.5e-06 26.7 0.2 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG35375.1 - 4.4e-05 24.1 0.0 0.00013 22.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 OAG35375.1 - 0.0058 16.6 0.0 0.0086 16.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAG35375.1 - 0.11 11.8 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family MTS PF05175.14 OAG35375.1 - 0.11 12.0 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.13 OAG35375.1 - 0.18 11.2 0.0 0.27 10.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Ebola_NP PF05505.12 OAG35375.1 - 0.18 10.1 1.5 0.26 9.6 1.5 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein SRP-alpha_N PF04086.13 OAG35376.1 - 1.7e-74 251.4 0.0 2.1e-74 251.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.22 OAG35376.1 - 3.4e-48 163.9 0.1 5.6e-48 163.2 0.1 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.19 OAG35376.1 - 7e-09 35.8 0.0 3e-08 33.7 0.0 2.1 2 0 0 2 2 1 1 SRP54-type protein, helical bundle domain MeaB PF03308.16 OAG35376.1 - 2.2e-07 30.1 0.0 4.4e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_24 PF13479.6 OAG35376.1 - 0.0011 18.7 0.0 0.017 14.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 OAG35376.1 - 0.0028 17.4 0.2 0.0087 15.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 OAG35376.1 - 0.0028 18.2 0.0 0.25 11.9 0.0 2.5 2 0 0 2 2 2 1 ABC transporter CbiA PF01656.23 OAG35376.1 - 0.0046 17.0 0.7 0.28 11.2 0.0 2.6 3 0 0 3 3 3 1 CobQ/CobB/MinD/ParA nucleotide binding domain MMR_HSR1 PF01926.23 OAG35376.1 - 0.0047 17.0 1.1 0.044 13.9 1.1 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_17 PF13207.6 OAG35376.1 - 0.018 15.5 0.3 0.073 13.5 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_31 PF13614.6 OAG35376.1 - 0.055 13.4 0.1 0.27 11.1 0.0 1.9 1 1 0 2 2 2 0 AAA domain Longin PF13774.6 OAG35376.1 - 0.11 12.6 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Regulated-SNARE-like domain AAA_29 PF13555.6 OAG35376.1 - 0.11 12.2 0.2 5.7 6.8 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain APS_kinase PF01583.20 OAG35376.1 - 0.13 12.1 0.0 0.36 10.7 0.0 1.7 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_5 PF07728.14 OAG35376.1 - 0.16 11.9 0.1 9 6.3 0.0 2.7 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AIM24 PF01987.17 OAG35377.1 - 3.7e-48 164.0 0.2 4.6e-48 163.7 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 Peptidase_M73 PF12389.8 OAG35377.1 - 0.49 10.2 2.8 0.97 9.2 2.8 1.4 1 0 0 1 1 1 0 Camelysin metallo-endopeptidase Peptidase_S41 PF03572.18 OAG35378.1 - 5.4e-10 39.1 0.0 1.2e-09 38.0 0.0 1.5 1 1 0 1 1 1 1 Peptidase family S41 BsuPI PF12690.7 OAG35378.1 - 0.051 13.6 0.1 0.6 10.2 0.0 2.4 1 1 1 2 2 2 0 Intracellular proteinase inhibitor TPR_12 PF13424.6 OAG35380.1 - 1.4e-08 34.9 2.0 1.3e-07 31.8 0.9 3.6 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 OAG35380.1 - 0.00068 19.4 7.7 0.036 13.9 0.1 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 OAG35380.1 - 0.0016 18.4 5.8 6.3 7.2 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 OAG35380.1 - 0.049 14.1 0.6 0.14 12.7 0.1 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 OAG35380.1 - 0.14 12.9 10.5 1.8 9.3 0.1 3.6 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 OAG35380.1 - 9.9 7.1 14.7 0.39 11.5 0.9 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF1479 PF07350.12 OAG35382.1 - 1.8e-161 537.6 0.0 2.1e-161 537.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) adh_short PF00106.25 OAG35383.1 - 2.5e-36 125.0 0.0 3.3e-36 124.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG35383.1 - 1.1e-31 110.2 0.0 1.5e-31 109.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG35383.1 - 4.8e-06 26.6 0.0 1.1e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 KR domain 2-Hacid_dh_C PF02826.19 OAG35383.1 - 0.028 13.8 0.0 0.044 13.1 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Ank_2 PF12796.7 OAG35383.1 - 0.14 12.8 0.0 24 5.6 0.0 3.0 3 1 0 3 3 3 0 Ankyrin repeats (3 copies) Aa_trans PF01490.18 OAG35384.1 - 2.4e-94 316.4 12.2 2.4e-94 316.4 12.2 1.7 2 0 0 2 2 2 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 OAG35384.1 - 0.00071 18.7 17.8 0.00071 18.7 17.8 1.7 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family YL1 PF05764.13 OAG35385.1 - 0.11 12.6 14.2 0.21 11.7 14.2 1.4 1 1 0 1 1 1 0 YL1 nuclear protein DNA_pol_phi PF04931.13 OAG35385.1 - 0.99 7.4 6.8 1.4 6.9 6.8 1.2 1 0 0 1 1 1 0 DNA polymerase phi DUF3824 PF12868.7 OAG35385.1 - 1.9 9.1 12.5 5.3 7.7 12.5 1.8 1 1 0 1 1 1 0 Domain of unknwon function (DUF3824) Bax1-I PF01027.20 OAG35386.1 - 2.3e-51 174.6 28.9 2.7e-51 174.4 28.9 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 SfLAP PF11139.8 OAG35386.1 - 0.031 13.7 1.3 0.031 13.7 1.3 2.6 2 2 1 3 3 3 0 Sap, sulfolipid-1-addressing protein Spore_YhaL PF14147.6 OAG35386.1 - 0.094 12.4 0.2 0.39 10.4 0.2 2.1 1 0 0 1 1 1 0 Sporulation protein YhaL HET PF06985.11 OAG35387.1 - 1.7e-24 86.8 0.0 3.9e-24 85.7 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) CorA PF01544.18 OAG35388.1 - 1.3e-10 41.1 0.2 2.1e-10 40.4 0.2 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein KxDL PF10241.9 OAG35388.1 - 0.028 14.7 0.3 1 9.7 0.0 2.7 3 0 0 3 3 3 0 Uncharacterized conserved protein Curto_V3 PF07436.11 OAG35388.1 - 0.062 13.7 0.1 0.16 12.3 0.1 1.7 1 0 0 1 1 1 0 Curtovirus V3 protein DUF1772 PF08592.11 OAG35388.1 - 0.11 12.8 0.1 0.2 12.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) SieB PF14163.6 OAG35388.1 - 0.3 10.6 3.9 0.84 9.1 3.9 1.7 1 1 0 1 1 1 0 Super-infection exclusion protein B FtsX PF02687.21 OAG35388.1 - 0.93 10.0 5.4 1.7 9.2 5.4 1.3 1 0 0 1 1 1 0 FtsX-like permease family RyR PF02026.16 OAG35389.1 - 7.4e-08 32.5 0.1 3.5e-06 27.1 0.0 2.5 2 0 0 2 2 2 1 RyR domain AAA_16 PF13191.6 OAG35389.1 - 0.0043 17.4 0.0 0.022 15.2 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 OAG35389.1 - 0.0053 17.0 0.0 0.02 15.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 OAG35389.1 - 0.14 12.6 0.0 0.33 11.4 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sacchrp_dh_C PF16653.5 OAG35390.1 - 1e-96 324.1 0.0 1.8e-96 323.4 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 OAG35390.1 - 3.9e-24 85.4 0.3 5.8e-24 84.8 0.3 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 OAG35390.1 - 1.8e-07 31.3 0.1 3.7e-07 30.3 0.1 1.6 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.6 OAG35390.1 - 0.00065 19.6 0.2 0.0028 17.6 0.1 1.9 2 0 0 2 2 2 1 NAD(P)H-binding Methyltransf_23 PF13489.6 OAG35391.1 - 7.1e-09 35.7 0.0 1.1e-08 35.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG35391.1 - 0.0015 19.3 0.0 0.0033 18.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG35391.1 - 0.013 16.2 0.0 0.074 13.8 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 OAG35391.1 - 0.074 13.7 0.0 0.15 12.7 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_17 PF12692.7 OAG35391.1 - 0.16 12.0 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-methionine methyltransferase Ribosomal_L28e PF01778.17 OAG35392.1 - 8.3e-36 123.2 0.2 1.6e-35 122.3 0.2 1.5 1 0 0 1 1 1 1 Ribosomal L28e protein family Mak16 PF04874.14 OAG35392.1 - 4.6e-25 88.1 18.5 4.6e-25 88.1 18.5 2.5 1 1 1 2 2 2 1 Mak16 protein C-terminal region BUD22 PF09073.10 OAG35392.1 - 8.5e-07 28.7 19.0 1.1e-06 28.3 19.0 1.0 1 0 0 1 1 1 1 BUD22 PYC_OADA PF02436.18 OAG35392.1 - 0.02 14.6 0.8 0.033 13.9 0.8 1.4 1 0 0 1 1 1 0 Conserved carboxylase domain VHS PF00790.19 OAG35393.1 - 8e-33 113.3 2.4 1.3e-32 112.5 2.4 1.4 1 0 0 1 1 1 1 VHS domain SH3_1 PF00018.28 OAG35393.1 - 2e-16 59.3 0.0 4.6e-16 58.2 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 OAG35393.1 - 7.6e-15 54.5 0.1 1.5e-14 53.6 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 OAG35393.1 - 2.8e-14 52.5 0.0 4.9e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain GAT PF03127.14 OAG35393.1 - 2.1e-10 40.8 2.1 2.5e-10 40.5 0.6 1.9 2 0 0 2 2 2 1 GAT domain UIM PF02809.20 OAG35393.1 - 0.12 12.4 3.6 0.27 11.3 3.6 1.7 1 0 0 1 1 1 0 Ubiquitin interaction motif DUF445 PF04286.12 OAG35393.1 - 1.4 8.7 4.5 0.19 11.5 0.5 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF445) Cyt-b5 PF00173.28 OAG35394.1 - 2e-23 82.3 0.2 2.8e-23 81.8 0.2 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Myb_DNA-bind_2 PF08914.11 OAG35395.1 - 1.1e-15 57.6 2.4 4.2e-15 55.7 2.4 2.1 1 0 0 1 1 1 1 Rap1 Myb domain Rap1_C PF11626.8 OAG35395.1 - 2.8e-12 46.5 0.7 4.7e-11 42.6 0.1 3.0 2 1 0 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain GATA PF00320.27 OAG35395.1 - 6.7e-07 28.8 1.8 1.3e-06 27.9 1.8 1.5 1 0 0 1 1 1 1 GATA zinc finger Rap1-DNA-bind PF09197.10 OAG35395.1 - 0.00016 22.3 1.8 0.00097 19.7 0.3 3.0 2 0 0 2 2 2 1 Rap1, DNA-binding ArfGap PF01412.18 OAG35395.1 - 0.00082 19.4 0.1 0.00082 19.4 0.1 2.5 3 0 0 3 3 3 1 Putative GTPase activating protein for Arf BRCT_2 PF16589.5 OAG35395.1 - 0.0086 16.5 0.0 0.027 14.9 0.0 1.9 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Chromo_shadow PF01393.19 OAG35396.1 - 1.2e-16 60.5 1.0 4.3e-14 52.3 0.1 2.3 2 0 0 2 2 2 2 Chromo shadow domain Chromo PF00385.24 OAG35396.1 - 9.3e-16 57.5 0.7 9.3e-16 57.5 0.7 1.9 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Cpn60_TCP1 PF00118.24 OAG35397.1 - 6.5e-158 526.4 5.5 7.4e-158 526.2 5.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Resolvase PF00239.21 OAG35397.1 - 0.1 12.7 0.3 0.7 10.0 0.1 2.3 2 0 0 2 2 2 0 Resolvase, N terminal domain Enolase_N PF03952.16 OAG35397.1 - 0.26 11.4 2.7 13 6.0 0.2 3.2 3 0 0 3 3 3 0 Enolase, N-terminal domain bZIP_1 PF00170.21 OAG35398.1 - 4.6 7.4 7.5 10 6.3 7.5 1.5 1 0 0 1 1 1 0 bZIP transcription factor zf-CHY PF05495.12 OAG35399.1 - 8.8e-11 42.1 12.5 8.8e-11 42.1 12.5 3.4 3 1 0 3 3 3 1 CHY zinc finger zinc_ribbon_4 PF13717.6 OAG35399.1 - 0.35 10.8 7.5 5.9 6.9 1.0 4.3 3 1 1 4 4 4 0 zinc-ribbon domain DZR PF12773.7 OAG35399.1 - 5.4 7.1 18.9 9.1 6.4 0.2 3.8 3 1 0 3 3 3 0 Double zinc ribbon zinc_ribbon_15 PF17032.5 OAG35399.1 - 6.3 7.6 16.4 7 7.5 0.1 3.4 3 0 0 3 3 3 0 zinc-ribbon family DUF3295 PF11702.8 OAG35400.1 - 1.8e-90 304.7 17.0 2.1e-90 304.5 17.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3295) DNA_pol_phi PF04931.13 OAG35400.1 - 0.6 8.1 9.4 0.84 7.7 9.4 1.2 1 0 0 1 1 1 0 DNA polymerase phi Ala_racemase_N PF01168.20 OAG35401.1 - 1.1e-18 67.7 0.0 1.6e-18 67.2 0.0 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain D-ser_dehydrat PF14031.6 OAG35401.1 - 2.4e-15 56.9 0.0 4.9e-14 52.8 0.0 2.8 2 1 0 2 2 2 1 Putative serine dehydratase domain CheZ PF04344.13 OAG35402.1 - 0.0042 17.0 0.7 0.015 15.3 0.6 2.0 1 1 0 1 1 1 1 Chemotaxis phosphatase, CheZ RP-C_C PF11800.8 OAG35402.1 - 0.024 14.7 0.7 0.08 13.0 0.7 1.8 1 0 0 1 1 1 0 Replication protein C C-terminal region DUF2087 PF09860.9 OAG35402.1 - 0.15 12.2 0.2 9.9 6.4 0.0 2.9 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2087) PP2C PF00481.21 OAG35403.1 - 2e-52 178.4 0.0 3.3e-52 177.7 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_8 PF13855.6 OAG35403.1 - 1.8e-40 136.5 54.1 1.2e-07 31.4 0.3 10.8 7 2 4 12 12 12 9 Leucine rich repeat LRR_4 PF12799.7 OAG35403.1 - 9.7e-35 118.0 65.4 0.00026 21.3 0.5 12.6 12 1 1 13 13 13 10 Leucine Rich repeats (2 copies) Guanylate_cyc PF00211.20 OAG35403.1 - 4.1e-26 91.7 0.0 5.7e-25 88.0 0.0 2.3 1 1 1 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain LRR_9 PF14580.6 OAG35403.1 - 8.7e-07 28.6 23.3 0.018 14.5 0.6 6.1 2 2 4 6 6 6 5 Leucine-rich repeat Ad_cyc_g-alpha PF08509.11 OAG35403.1 - 1.4e-06 27.9 0.0 5.4e-06 26.0 0.0 2.1 1 0 0 1 1 1 1 Adenylate cyclase G-alpha binding domain RA PF00788.23 OAG35403.1 - 4.9e-05 23.9 0.0 0.00016 22.2 0.0 1.8 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain LRR_1 PF00560.33 OAG35403.1 - 0.00017 21.6 54.7 9.4 7.2 0.1 16.1 17 1 0 17 17 17 1 Leucine Rich Repeat DUF3600 PF12207.8 OAG35403.1 - 0.18 11.7 0.1 1.4 8.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3600) Glyco_hydro_31 PF01055.26 OAG35404.1 - 2.4e-99 333.5 6.5 3.6e-99 332.9 6.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 DUF4968 PF16338.5 OAG35404.1 - 0.0069 16.7 0.0 0.017 15.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4968) CBM_4_9 PF02018.17 OAG35404.1 - 0.11 12.8 0.0 0.28 11.4 0.0 1.7 1 0 0 1 1 1 0 Carbohydrate binding domain Abhydrolase_1 PF00561.20 OAG35405.1 - 3.4e-30 105.6 0.4 8.1e-29 101.0 0.4 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG35405.1 - 1.3e-17 65.2 0.2 2.3e-17 64.4 0.2 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG35405.1 - 2e-11 43.6 0.0 3.7e-11 42.7 0.0 1.4 2 0 0 2 2 2 1 Serine aminopeptidase, S33 AA_permease_2 PF13520.6 OAG35406.1 - 2.7e-81 273.6 42.5 3.4e-81 273.2 42.5 1.1 1 0 0 1 1 1 1 Amino acid permease Annexin PF00191.20 OAG35408.1 - 9e-63 208.3 1.8 2.9e-18 65.7 0.0 4.2 4 0 0 4 4 4 4 Annexin Acetyltransf_11 PF13720.6 OAG35408.1 - 0.0074 16.7 2.6 1.6 9.3 0.0 3.6 4 0 0 4 4 4 2 Udp N-acetylglucosamine O-acyltransferase; Domain 2 DUF374 PF04028.13 OAG35409.1 - 0.61 9.7 2.3 1.6 8.4 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF374) Mito_carr PF00153.27 OAG35410.1 - 4e-69 228.6 1.9 2.5e-22 78.6 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein MFS_1 PF07690.16 OAG35412.1 - 1.8e-22 79.8 27.6 1.8e-22 79.8 27.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Transp_cyt_pur PF02133.15 OAG35413.1 - 7.8e-98 328.1 29.7 8.9e-98 327.9 29.7 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF917 PF06032.12 OAG35414.1 - 6.6e-130 433.0 0.6 2.7e-127 424.4 0.1 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF917) Hydant_A_N PF05378.13 OAG35414.1 - 2e-30 105.8 0.3 2.5e-27 95.7 0.0 2.8 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region Hydantoinase_A PF01968.18 OAG35414.1 - 3.6e-28 98.6 5.8 4.7e-25 88.4 0.9 3.4 2 1 1 3 3 3 3 Hydantoinase/oxoprolinase FtsA PF14450.6 OAG35414.1 - 0.00017 22.0 1.0 0.049 14.1 0.0 3.1 3 0 0 3 3 3 1 Cell division protein FtsA MutL PF13941.6 OAG35414.1 - 0.00067 18.4 3.9 0.022 13.4 0.2 2.9 4 0 0 4 4 4 2 MutL protein ROK PF00480.20 OAG35414.1 - 0.0023 17.5 0.1 0.0068 15.9 0.1 1.8 1 0 0 1 1 1 1 ROK family BcrAD_BadFG PF01869.20 OAG35414.1 - 0.012 15.1 3.2 0.055 13.0 0.1 2.8 3 0 0 3 3 3 0 BadF/BadG/BcrA/BcrD ATPase family StbA PF06406.11 OAG35414.1 - 0.057 12.6 0.4 9.4 5.4 0.2 2.4 2 0 0 2 2 2 0 StbA protein Fungal_trans PF04082.18 OAG35415.1 - 3.5e-13 49.2 0.0 6.6e-13 48.3 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ndc80_HEC PF03801.13 OAG35415.1 - 0.091 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 HEC/Ndc80p family Fungal_trans PF04082.18 OAG35416.1 - 0.0085 15.2 0.3 0.017 14.2 0.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain KTI12 PF08433.10 OAG35420.1 - 1.8e-61 208.0 0.0 8.2e-61 205.8 0.0 2.1 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 OAG35420.1 - 1.7e-08 34.8 0.1 4.3e-07 30.2 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 OAG35420.1 - 0.016 15.7 0.0 0.035 14.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain Methyltransf_16 PF10294.9 OAG35422.1 - 8.9e-18 64.6 0.0 1.2e-17 64.2 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase GidB PF02527.15 OAG35422.1 - 0.003 16.9 0.0 0.0045 16.3 0.0 1.2 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G PrmA PF06325.13 OAG35422.1 - 0.004 16.6 0.0 0.0053 16.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 OAG35422.1 - 0.064 14.0 0.1 0.19 12.4 0.1 1.8 1 1 0 1 1 1 0 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 OAG35422.1 - 0.12 11.5 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Glyco_hydro_16 PF00722.21 OAG35423.1 - 3.9e-11 42.7 0.1 8.1e-11 41.7 0.1 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 MFS_1 PF07690.16 OAG35424.1 - 1.9e-05 23.7 10.6 2.4e-05 23.4 10.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily SnoaL_4 PF13577.6 OAG35425.1 - 8.5e-23 80.9 0.4 1.1e-22 80.6 0.4 1.1 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 OAG35425.1 - 1.6e-06 28.5 0.4 2.3e-06 27.9 0.4 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_2 PF12680.7 OAG35425.1 - 1e-05 26.1 0.4 1.7e-05 25.4 0.4 1.4 1 1 0 1 1 1 1 SnoaL-like domain SnoaL_3 PF13474.6 OAG35425.1 - 0.043 14.1 0.3 0.061 13.6 0.3 1.2 1 0 0 1 1 1 0 SnoaL-like domain Fungal_trans PF04082.18 OAG35426.1 - 3e-31 108.4 0.5 4.1e-31 108.0 0.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG35426.1 - 6.8e-07 29.3 5.5 1.4e-06 28.3 5.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Epimerase PF01370.21 OAG35428.1 - 1.2e-13 51.2 0.0 1.5e-13 50.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 OAG35428.1 - 2.6e-08 33.3 0.1 3.9e-08 32.8 0.1 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.13 OAG35428.1 - 1.5e-06 27.9 0.3 0.0013 18.3 0.1 2.2 2 0 0 2 2 2 2 NmrA-like family GDP_Man_Dehyd PF16363.5 OAG35428.1 - 0.0023 17.4 0.0 0.31 10.4 0.0 2.3 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 OAG35428.1 - 0.011 14.7 0.2 0.38 9.7 0.0 2.1 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF4974 PF16344.5 OAG35428.1 - 0.04 13.9 0.1 0.074 13.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4974) TrkA_N PF02254.18 OAG35428.1 - 0.068 13.4 0.0 0.29 11.4 0.0 1.9 2 0 0 2 2 2 0 TrkA-N domain Palm_thioest PF02089.15 OAG35429.1 - 2.7e-78 263.2 0.0 3.2e-78 262.9 0.0 1.1 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF915 PF06028.11 OAG35429.1 - 0.0023 17.3 0.0 0.0045 16.3 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Lipase_2 PF01674.18 OAG35429.1 - 0.031 13.8 0.0 0.15 11.5 0.0 1.9 1 1 0 1 1 1 0 Lipase (class 2) Acetyltransf_1 PF00583.25 OAG35430.1 - 2.1e-08 34.4 0.0 3.1e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OAG35430.1 - 2.5e-06 27.8 0.0 3.7e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OAG35430.1 - 2.1e-05 24.4 0.0 2.9e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAG35430.1 - 0.0094 15.9 0.0 0.022 14.7 0.0 1.6 1 1 0 1 1 1 1 FR47-like protein Tox-MPTase3 PF15639.6 OAG35431.1 - 0.16 11.8 0.1 0.27 11.1 0.1 1.3 1 0 0 1 1 1 0 Metallopeptidase toxin 3 GFO_IDH_MocA PF01408.22 OAG35432.1 - 1.3e-21 77.7 0.1 2.1e-21 77.0 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 OAG35432.1 - 2e-07 31.0 0.0 4.1e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 OAG35432.1 - 0.041 14.5 0.0 0.069 13.8 0.0 1.3 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain DUF3176 PF11374.8 OAG35433.1 - 0.0023 18.1 0.7 0.0089 16.2 0.7 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) SnoaL PF07366.12 OAG35434.1 - 8.2e-07 28.9 0.0 2.2e-06 27.5 0.0 1.7 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase Ank_2 PF12796.7 OAG35435.1 - 1e-14 54.8 0.9 0.00037 21.0 0.0 5.0 3 1 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAG35435.1 - 3.1e-12 46.8 1.7 0.02 15.5 0.0 5.6 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG35435.1 - 5.1e-10 38.7 2.1 0.031 14.8 0.0 6.8 7 0 0 7 7 7 2 Ankyrin repeat Ank_5 PF13857.6 OAG35435.1 - 7.2e-06 26.2 3.1 1.3 9.4 0.0 4.9 5 0 0 5 5 5 2 Ankyrin repeats (many copies) Ank PF00023.30 OAG35435.1 - 1.9e-05 24.9 3.3 0.16 12.5 0.0 5.0 6 0 0 6 6 6 2 Ankyrin repeat DUF3447 PF11929.8 OAG35435.1 - 0.13 12.2 0.0 1.2 9.1 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF3447) COesterase PF00135.28 OAG35436.1 - 1.3e-90 304.7 0.3 1.7e-90 304.3 0.3 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAG35436.1 - 0.067 13.0 0.1 0.13 12.1 0.1 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold BING4CT PF08149.11 OAG35437.1 - 1.8e-40 136.6 1.4 7.3e-36 121.8 0.0 3.4 4 0 0 4 4 4 2 BING4CT (NUC141) domain WD40 PF00400.32 OAG35437.1 - 2.9e-06 27.9 0.9 0.012 16.4 0.0 4.1 4 1 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG35437.1 - 4e-06 27.0 0.0 1.4 9.3 0.0 5.0 2 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain cobW PF02492.19 OAG35438.1 - 3.3e-34 118.0 0.0 4.2e-34 117.7 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 OAG35438.1 - 1.2e-05 24.4 0.3 0.003 16.6 0.1 2.1 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB PRK PF00485.18 OAG35438.1 - 0.0044 16.8 0.0 1.1 8.9 0.0 2.5 2 1 0 3 3 3 2 Phosphoribulokinase / Uridine kinase family MMR_HSR1 PF01926.23 OAG35438.1 - 0.011 15.8 0.0 0.04 14.0 0.0 2.1 2 1 0 2 2 2 0 50S ribosome-binding GTPase CbiA PF01656.23 OAG35438.1 - 0.089 12.8 0.0 0.27 11.3 0.0 1.9 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_5 PF07728.14 OAG35438.1 - 0.092 12.7 0.0 0.2 11.6 0.0 1.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_23 PF13476.6 OAG35438.1 - 0.16 12.5 0.0 0.22 12.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 OAG35438.1 - 0.16 12.0 0.0 0.24 11.4 0.0 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit NACHT PF05729.12 OAG35438.1 - 0.17 11.8 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 NACHT domain Fe-S_biosyn PF01521.20 OAG35439.1 - 1.1e-19 70.6 0.0 1.6e-19 70.2 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis DUF1741 PF08427.10 OAG35440.1 - 8.9e-74 248.1 0.0 1.6e-73 247.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1741) adh_short_C2 PF13561.6 OAG35441.1 - 3.2e-57 193.8 0.7 4.9e-57 193.2 0.7 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG35441.1 - 9.3e-50 168.8 1.3 1.2e-49 168.4 1.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG35441.1 - 2.3e-14 53.7 0.3 3e-14 53.3 0.3 1.1 1 0 0 1 1 1 1 KR domain DUF1372 PF07116.11 OAG35441.1 - 0.011 15.9 0.1 0.023 14.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1372) DFP PF04127.15 OAG35441.1 - 0.039 13.8 0.5 0.11 12.4 0.5 1.6 1 1 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein 3HCDH_N PF02737.18 OAG35441.1 - 0.14 12.0 0.6 0.31 10.9 0.7 1.5 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GCFC PF07842.12 OAG35442.1 - 2.4e-30 106.1 3.2 2.4e-30 106.1 3.2 1.8 2 0 0 2 2 2 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.23 OAG35442.1 - 1.8e-15 56.5 2.5 5.6e-15 55.0 2.5 1.9 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 OAG35442.1 - 0.00095 19.2 6.7 0.054 13.6 0.8 2.6 2 0 0 2 2 2 2 G-patch domain Sod_Fe_C PF02777.18 OAG35443.1 - 8.2e-37 125.5 0.5 8.2e-37 125.5 0.5 1.5 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 OAG35443.1 - 2.9e-29 101.4 1.3 4.9e-29 100.6 1.3 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain GFA PF04828.14 OAG35444.1 - 2.5e-18 66.2 8.0 5.7e-10 39.4 0.1 2.7 3 0 0 3 3 3 2 Glutathione-dependent formaldehyde-activating enzyme zf_UBZ PF18439.1 OAG35444.1 - 0.024 14.2 1.3 7 6.3 0.1 2.7 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-RRN7 PF11781.8 OAG35444.1 - 0.43 10.3 6.9 8.5 6.2 0.2 3.5 3 0 0 3 3 3 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 NOB1_Zn_bind PF08772.11 OAG35444.1 - 1.9 8.7 11.5 1.2 9.4 0.1 3.6 4 0 0 4 4 4 0 Nin one binding (NOB1) Zn-ribbon like zinc_ribbon_2 PF13240.6 OAG35444.1 - 8.8 6.2 11.7 4.2 7.2 0.1 3.8 4 0 0 4 4 4 0 zinc-ribbon domain TauD PF02668.16 OAG35446.1 - 2.3e-46 158.8 0.1 3e-46 158.4 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Plasmod_MYXSPDY PF07981.11 OAG35446.1 - 0.065 13.2 0.3 0.13 12.3 0.3 1.4 1 0 0 1 1 1 0 Plasmodium repeat_MYXSPDY Fungal_trans PF04082.18 OAG35447.1 - 6.7e-29 100.7 0.0 1.1e-28 100.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF2985 PF11204.8 OAG35449.1 - 1.8e-21 76.0 4.0 3.6e-21 75.1 4.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) Abhydrolase_3 PF07859.13 OAG35451.1 - 2.2e-56 191.1 0.3 3.8e-56 190.3 0.3 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 OAG35451.1 - 0.0017 17.3 0.0 0.0025 16.8 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 OAG35451.1 - 0.013 15.0 0.2 0.62 9.5 0.2 2.3 1 1 0 1 1 1 0 Prolyl oligopeptidase family COesterase PF00135.28 OAG35451.1 - 0.043 12.7 2.2 0.18 10.6 2.2 1.8 1 1 0 1 1 1 0 Carboxylesterase family DLH PF01738.18 OAG35451.1 - 0.075 12.6 0.0 0.19 11.3 0.0 1.8 1 0 0 1 1 1 0 Dienelactone hydrolase family DUF2974 PF11187.8 OAG35451.1 - 0.16 11.5 0.0 0.27 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Pyr_redox_3 PF13738.6 OAG35452.1 - 2.1e-14 53.5 0.0 1.7e-13 50.5 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 OAG35452.1 - 4.2e-13 48.6 0.0 1.4e-12 46.8 0.0 1.7 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 OAG35452.1 - 3e-11 43.1 0.0 1.2e-09 37.8 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG35452.1 - 1.2e-08 35.0 0.1 2e-07 31.2 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 OAG35452.1 - 1.3e-08 34.4 0.0 2.4e-06 26.9 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.24 OAG35452.1 - 0.00081 18.6 0.0 0.0017 17.6 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 OAG35452.1 - 0.0045 17.5 0.1 1.5 9.5 0.0 2.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 OAG35452.1 - 0.0085 16.2 0.0 0.063 13.3 0.0 2.2 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase DAO PF01266.24 OAG35452.1 - 0.032 13.8 0.5 5.6 6.5 0.0 2.4 1 1 1 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.17 OAG35452.1 - 0.066 12.4 0.0 0.24 10.6 0.0 1.8 2 0 0 2 2 2 0 Thi4 family Lycopene_cycl PF05834.12 OAG35452.1 - 0.084 11.9 0.0 0.18 10.8 0.0 1.6 1 0 0 1 1 1 0 Lycopene cyclase protein HI0933_like PF03486.14 OAG35452.1 - 0.14 10.8 0.0 0.36 9.5 0.0 1.6 2 0 0 2 2 2 0 HI0933-like protein ADH_zinc_N PF00107.26 OAG35453.1 - 1.2e-22 80.2 0.0 2e-22 79.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG35453.1 - 1.3e-20 73.3 4.1 2.1e-20 72.6 4.1 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 OAG35453.1 - 1.2e-09 38.0 0.0 1.6e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 OAG35453.1 - 9.6e-05 23.4 0.0 0.00016 22.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 OAG35453.1 - 0.16 11.3 0.0 0.25 10.7 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TruD PF01142.18 OAG35454.1 - 2.8e-63 214.2 0.3 6.8e-59 199.7 0.1 3.9 3 1 0 3 3 3 3 tRNA pseudouridine synthase D (TruD) Erf4 PF10256.9 OAG35455.1 - 0.028 14.5 0.0 0.064 13.4 0.0 1.6 1 0 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family MRNIP PF15749.5 OAG35456.1 - 0.19 12.5 1.7 0.49 11.1 1.7 1.6 1 0 0 1 1 1 0 MRN-interacting protein Acyl-CoA_dh_2 PF08028.11 OAG35457.1 - 2.4e-20 73.2 1.9 4e-20 72.5 1.9 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 OAG35457.1 - 1.2e-10 42.0 0.0 2.7e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 OAG35457.1 - 2.9e-06 27.4 0.0 7.2e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 OAG35457.1 - 1.7e-05 25.1 0.2 3.3e-05 24.1 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Potex_coat PF06184.11 OAG35457.1 - 0.079 12.5 0.1 0.18 11.4 0.1 1.6 1 0 0 1 1 1 0 Potexvirus coat protein Bac_luciferase PF00296.20 OAG35458.1 - 5.3e-65 219.9 0.0 8.7e-65 219.2 0.0 1.2 1 0 0 1 1 1 1 Luciferase-like monooxygenase AIM3 PF17096.5 OAG35459.1 - 0.0079 17.1 0.0 0.0079 17.1 0.0 5.1 5 1 0 5 5 5 2 Altered inheritance of mitochondria protein 3 DUF148 PF02520.17 OAG35459.1 - 3.3 7.9 4.4 8.4 6.5 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function DUF148 DUF4448 PF14610.6 OAG35460.1 - 0.00044 20.1 0.0 0.00065 19.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) DUF1180 PF06679.12 OAG35460.1 - 0.0077 16.7 7.8 0.0077 16.7 7.8 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF1180) SKG6 PF08693.10 OAG35460.1 - 0.022 14.2 5.3 0.052 13.0 5.3 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Syndecan PF01034.20 OAG35460.1 - 0.097 12.6 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Syndecan domain TMEM154 PF15102.6 OAG35460.1 - 0.4 10.6 4.5 2.1 8.2 4.5 2.1 1 1 0 1 1 1 0 TMEM154 protein family MFS_1 PF07690.16 OAG35461.1 - 2.3e-40 138.6 29.4 2.3e-40 138.6 29.4 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG35461.1 - 2.5e-07 30.0 22.7 5e-07 28.9 22.7 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter FTA2 PF13095.6 OAG35463.1 - 3.9e-12 46.3 0.0 5.5e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 VPS28 PF03997.12 OAG35464.1 - 2.9e-67 226.0 0.1 3.4e-67 225.8 0.1 1.0 1 0 0 1 1 1 1 VPS28 protein Noc2 PF03715.13 OAG35465.1 - 3.3e-124 414.0 0.2 7.6e-124 412.8 0.2 1.6 1 0 0 1 1 1 1 Noc2p family XPC-binding PF09280.11 OAG35465.1 - 0.053 13.3 0.0 9.4 6.1 0.0 3.0 2 0 0 2 2 2 0 XPC-binding domain SIP1 PF04938.12 OAG35465.1 - 0.26 11.0 10.7 0.78 9.4 0.0 3.1 3 0 0 3 3 3 0 Survival motor neuron (SMN) interacting protein 1 (SIP1) Glycos_transf_1 PF00534.20 OAG35466.1 - 6e-17 61.7 0.0 2e-16 60.0 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 OAG35466.1 - 1.1e-10 42.1 0.0 2.1e-10 41.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 OAG35466.1 - 3.6e-05 24.1 0.0 9.8e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF2520 PF10728.9 OAG35466.1 - 0.12 12.2 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2520) DUF3328 PF11807.8 OAG35468.1 - 6.4e-20 71.9 1.7 6.4e-20 71.9 1.7 2.1 2 1 1 3 3 3 1 Domain of unknown function (DUF3328) NolB PF17398.2 OAG35469.1 - 0.0035 17.7 7.1 27 5.1 0.3 5.2 1 1 5 6 6 6 1 Nodulation protein NolB Mif2_N PF15624.6 OAG35469.1 - 0.012 16.3 11.3 1.6 9.4 2.5 3.2 1 1 2 3 3 3 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal DUF5031 PF16434.5 OAG35469.1 - 0.012 14.8 2.4 38 3.3 0.1 4.3 1 1 4 5 5 5 0 Domain of unknown function (DUF5031) MALT1_Ig PF18703.1 OAG35469.1 - 0.026 14.5 0.1 16 5.5 0.0 2.8 1 1 1 3 3 3 0 MALT1 Ig-like domain DUF4188 PF13826.6 OAG35469.1 - 0.26 11.7 5.6 37 4.7 0.3 4.2 1 1 4 5 5 5 0 Domain of unknown function (DUF4188) DIM PF08194.12 OAG35469.1 - 0.29 11.3 2.1 0.48 10.7 2.1 1.3 1 0 0 1 1 1 0 DIM protein Pkinase PF00069.25 OAG35470.1 - 2.2e-38 132.2 0.0 2.8e-38 131.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG35470.1 - 6e-16 58.5 0.0 1.3e-15 57.4 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 OAG35470.1 - 2.1e-05 24.6 0.1 0.0028 17.6 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 OAG35470.1 - 5.1e-05 22.7 0.0 0.00014 21.3 0.0 1.6 1 1 1 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OAG35470.1 - 0.0014 18.0 0.0 0.002 17.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 OAG35470.1 - 0.0047 16.6 0.0 0.0072 15.9 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Fungal_trans_2 PF11951.8 OAG35472.1 - 2.1e-10 40.0 0.3 3.4e-10 39.3 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain VirB7 PF17413.2 OAG35472.1 - 0.11 11.8 0.0 0.31 10.4 0.0 1.7 1 0 0 1 1 1 0 Outer membrane lipoprotein virB7 RTA1 PF04479.13 OAG35473.1 - 4.4e-66 222.4 10.7 5.7e-66 222.1 10.7 1.1 1 0 0 1 1 1 1 RTA1 like protein DUF423 PF04241.15 OAG35473.1 - 0.71 10.1 5.8 0.57 10.4 0.7 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF423) BaxI_1 PF12811.7 OAG35473.1 - 0.73 9.4 7.8 0.52 9.8 2.2 2.4 1 1 1 2 2 2 0 Bax inhibitor 1 like ADH_zinc_N_2 PF13602.6 OAG35474.1 - 5.3e-29 102.0 0.0 8.7e-29 101.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 OAG35474.1 - 1.4e-15 57.4 0.4 3.3e-15 56.2 0.3 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Glu_synthase PF01645.17 OAG35474.1 - 0.025 13.7 1.2 0.025 13.7 1.2 1.5 2 0 0 2 2 2 0 Conserved region in glutamate synthase HET PF06985.11 OAG35475.1 - 4.3e-22 79.0 0.1 1.3e-21 77.5 0.1 1.9 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF5346 PF17281.2 OAG35475.1 - 0.19 11.8 1.1 0.46 10.5 0.4 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5346) NTP_transf_6 PF06042.11 OAG35476.1 - 2.1e-35 121.9 0.0 3e-35 121.4 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyltransferase Sugar_tr PF00083.24 OAG35477.1 - 5.2e-86 289.3 30.6 6.1e-86 289.1 30.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG35477.1 - 3.7e-25 88.6 36.0 4.1e-25 88.4 31.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_5 PF05631.14 OAG35477.1 - 4.7e-06 25.8 7.3 2.2e-05 23.6 0.5 2.3 2 0 0 2 2 2 2 Sugar-tranasporters, 12 TM TRI12 PF06609.13 OAG35477.1 - 0.00012 20.7 3.0 0.00026 19.6 0.1 2.3 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Cu-oxidase_2 PF07731.14 OAG35478.1 - 1e-44 151.6 10.1 8.8e-40 135.6 1.7 3.6 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 OAG35478.1 - 4.5e-42 142.8 4.4 2e-39 134.3 0.7 3.4 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 OAG35478.1 - 8e-41 139.8 4.2 4.2e-34 118.0 0.4 3.2 3 0 0 3 3 3 3 Multicopper oxidase Cupredoxin_1 PF13473.6 OAG35478.1 - 0.027 14.6 0.0 24 5.1 0.0 3.5 3 1 0 3 3 3 0 Cupredoxin-like domain Self-incomp_S1 PF05938.11 OAG35478.1 - 0.046 14.3 0.2 18 5.9 0.0 2.4 2 0 0 2 2 2 0 Plant self-incompatibility protein S1 FTR1 PF03239.14 OAG35479.1 - 2.7e-87 292.8 8.4 3.2e-87 292.5 8.4 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family Ldr_toxin PF13940.6 OAG35479.1 - 0.045 13.8 0.5 0.045 13.8 0.5 2.7 3 0 0 3 3 3 0 Toxin Ldr, type I toxin-antitoxin system Herpes_US9 PF06072.11 OAG35479.1 - 0.073 13.0 0.0 0.33 10.9 0.0 2.2 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 DUF1218 PF06749.12 OAG35479.1 - 2.1 8.9 6.8 21 5.7 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1218) S_2TMBeta PF18153.1 OAG35479.1 - 2.4 7.9 7.7 0.097 12.4 1.1 2.0 2 1 1 3 3 3 0 SMODS-associating 2TM, beta-strand rich effector domain 2OG-Fe_Oxy_2 PF10014.9 OAG35480.1 - 0.00054 19.8 0.1 0.0015 18.4 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe dioxygenase 2OG-FeII_Oxy_3 PF13640.6 OAG35480.1 - 0.0007 20.4 0.0 0.0012 19.7 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF2948 PF11164.8 OAG35480.1 - 0.14 12.2 0.2 0.23 11.5 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2948) Fungal_trans_2 PF11951.8 OAG35481.1 - 2.6e-17 62.7 0.2 5.7e-16 58.3 0.2 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG35481.1 - 1.3e-08 34.8 4.2 3e-08 33.6 4.2 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_L37ae PF01780.19 OAG35481.1 - 0.21 11.7 0.7 0.51 10.5 0.7 1.6 1 0 0 1 1 1 0 Ribosomal L37ae protein family OTT_1508_deam PF14441.6 OAG35482.1 - 3e-18 65.6 0.0 6e-18 64.6 0.0 1.5 1 0 0 1 1 1 1 OTT_1508-like deaminase MFS_1 PF07690.16 OAG35483.1 - 7.3e-45 153.4 45.0 7.4e-44 150.1 45.4 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 OAG35483.1 - 1.1e-13 50.5 20.6 1.5e-13 50.1 20.6 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 OAG35483.1 - 0.0008 17.8 0.9 0.0008 17.8 0.9 3.1 3 1 0 4 4 4 2 Organic Anion Transporter Polypeptide (OATP) family Peptidase_M16 PF00675.20 OAG35486.1 - 8.4e-56 188.1 0.1 1e-54 184.6 0.1 2.3 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 OAG35486.1 - 1.6e-37 129.3 0.0 9.1e-37 126.8 0.0 2.0 2 0 0 2 2 2 1 Peptidase M16 inactive domain ACOX PF01756.19 OAG35487.1 - 0.031 13.9 0.0 0.17 11.5 0.0 2.2 1 1 1 2 2 2 0 Acyl-CoA oxidase DUF5106 PF17127.4 OAG35487.1 - 0.11 12.8 0.1 0.56 10.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5106) FMO-like PF00743.19 OAG35488.1 - 4.8e-19 68.2 0.4 5.4e-14 51.5 0.0 3.2 2 2 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OAG35488.1 - 3.5e-12 46.4 0.0 8.2e-12 45.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 OAG35488.1 - 6.9e-09 35.3 0.0 1.7e-06 27.4 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 OAG35488.1 - 7e-07 28.8 0.0 7.8e-06 25.3 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAG35488.1 - 8.8e-06 25.2 0.0 0.0022 17.3 0.0 2.7 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAG35488.1 - 0.012 14.8 0.0 0.041 13.1 0.0 1.8 2 0 0 2 2 2 0 Thi4 family NAD_binding_9 PF13454.6 OAG35488.1 - 0.012 15.6 2.1 0.39 10.7 0.0 3.0 3 0 0 3 3 3 0 FAD-NAD(P)-binding DAO PF01266.24 OAG35488.1 - 0.026 14.1 0.6 0.35 10.4 0.6 2.5 1 1 0 1 1 1 0 FAD dependent oxidoreductase CybS PF05328.12 OAG35489.1 - 9e-50 167.8 0.0 1.1e-49 167.5 0.0 1.1 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit Sdh_cyt PF01127.22 OAG35489.1 - 0.0052 16.8 4.1 0.054 13.5 4.1 2.1 1 1 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit A1_Propeptide PF07966.12 OAG35489.1 - 0.24 11.3 1.8 0.49 10.3 1.8 1.5 1 0 0 1 1 1 0 A1 Propeptide Maf PF02545.14 OAG35490.1 - 3.3e-51 173.4 0.0 3.9e-51 173.2 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein GFA PF04828.14 OAG35491.1 - 0.08 13.3 0.0 0.18 12.2 0.0 1.6 1 0 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme zinc_ribbon_2 PF13240.6 OAG35491.1 - 0.18 11.6 0.5 0.18 11.6 0.5 1.9 2 0 0 2 2 2 0 zinc-ribbon domain HLH PF00010.26 OAG35492.1 - 0.00013 21.9 0.1 0.00013 21.9 0.1 2.0 2 1 0 2 2 2 1 Helix-loop-helix DNA-binding domain Macoilin PF09726.9 OAG35492.1 - 1.2 7.6 8.0 1.3 7.5 8.0 1.1 1 0 0 1 1 1 0 Macoilin family Ribonuc_L-PSP PF01042.21 OAG35495.1 - 1.8e-30 105.5 0.0 2.3e-30 105.1 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP FUSC PF04632.12 OAG35496.1 - 5.5 5.4 5.4 6.6 5.1 5.4 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family MFS_1 PF07690.16 OAG35498.1 - 3.9e-35 121.4 36.9 5.7e-35 120.9 36.9 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG35498.1 - 3.2e-08 32.9 16.6 3.2e-08 32.9 16.6 2.5 2 1 1 3 3 3 1 Sugar (and other) transporter DUF3522 PF12036.8 OAG35498.1 - 0.063 13.6 2.5 0.12 12.7 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3522) DIOX_N PF14226.6 OAG35499.1 - 2.3e-20 73.5 0.0 3.9e-20 72.8 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OAG35499.1 - 1.9e-17 63.6 0.0 3.1e-17 62.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Sugar_tr PF00083.24 OAG35500.1 - 2.2e-91 307.0 22.3 2.7e-91 306.7 22.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG35500.1 - 3e-23 82.3 38.0 5.5e-20 71.6 15.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily HAD_2 PF13419.6 OAG35501.1 - 2.2e-06 27.9 0.0 3.6e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase DUF2608 PF11019.8 OAG35501.1 - 0.0093 15.5 0.0 0.016 14.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2608) Hydrolase_like PF13242.6 OAG35501.1 - 0.019 15.0 0.0 0.049 13.7 0.0 1.7 1 0 0 1 1 1 0 HAD-hyrolase-like Hydrolase PF00702.26 OAG35501.1 - 0.11 12.7 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase FAD_binding_4 PF01565.23 OAG35503.1 - 5e-20 71.7 0.7 1.1e-19 70.6 0.7 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 OAG35503.1 - 0.0075 16.3 0.3 0.024 14.7 0.2 2.0 2 0 0 2 2 2 1 Berberine and berberine like Lactamase_B PF00753.27 OAG35504.1 - 9.2e-11 42.1 4.0 7.7e-10 39.1 4.0 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OAG35504.1 - 0.00011 21.7 0.4 0.00027 20.5 0.4 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain AMPK1_CBM PF16561.5 OAG35504.1 - 0.00018 21.7 0.0 0.00037 20.7 0.0 1.5 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase DUF951 PF06107.11 OAG35504.1 - 0.049 13.5 1.1 0.093 12.7 1.1 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF951) Peptidase_S10 PF00450.22 OAG35505.1 - 1.9e-127 426.1 0.1 2.3e-127 425.9 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Carbpep_Y_N PF05388.11 OAG35505.1 - 2.7e-14 53.8 0.0 7e-14 52.4 0.0 1.7 1 0 0 1 1 1 1 Carboxypeptidase Y pro-peptide Euplotes_phero PF05842.11 OAG35505.1 - 0.019 15.5 0.5 0.043 14.4 0.5 1.6 1 1 0 1 1 1 0 Euplotes octocarinatus mating pheromone protein Ribosomal_S13 PF00416.22 OAG35506.1 - 9.9e-55 184.4 3.0 1.2e-54 184.2 3.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 OAG35506.1 - 0.033 12.9 0.0 0.045 12.5 0.0 1.2 1 1 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) HHH_6 PF14579.6 OAG35506.1 - 0.042 14.1 0.1 0.18 12.1 0.0 2.0 1 1 0 1 1 1 0 Helix-hairpin-helix motif 2OG-FeII_Oxy PF03171.20 OAG35508.1 - 1.4e-15 57.6 0.0 2.2e-15 56.9 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 OAG35508.1 - 3.9e-13 50.2 0.0 6e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Gpr1_Fun34_YaaH PF01184.19 OAG35509.1 - 2.9e-35 121.7 22.8 3.6e-35 121.5 22.8 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family FixP_N PF14715.6 OAG35509.1 - 1.9 8.3 0.0 1.9 8.3 0.0 3.6 4 1 1 5 5 5 0 N-terminal domain of cytochrome oxidase-cbb3, FixP Fungal_trans PF04082.18 OAG35510.1 - 4.6e-06 25.9 0.7 1.3e-05 24.4 0.7 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain FMO-like PF00743.19 OAG35511.1 - 5.4e-14 51.5 0.1 6.2e-13 48.0 0.0 2.3 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OAG35511.1 - 1.9e-10 40.8 0.0 4.8e-10 39.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 OAG35511.1 - 1.5e-08 34.2 0.0 4.5e-07 29.4 0.0 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG35511.1 - 3.7e-08 32.9 0.0 4.3e-05 22.8 0.0 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 OAG35511.1 - 9.1e-08 31.7 0.0 2.5e-05 23.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAG35511.1 - 0.00012 22.0 0.0 0.11 12.5 0.0 3.4 3 1 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.24 OAG35511.1 - 0.00072 19.2 0.0 0.45 10.0 0.0 3.1 3 0 0 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.17 OAG35511.1 - 0.074 12.3 0.0 0.45 9.7 0.0 2.0 2 0 0 2 2 2 0 Thi4 family Pyr_redox PF00070.27 OAG35511.1 - 0.14 12.7 0.0 15 6.2 0.0 2.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Aminotran_3 PF00202.21 OAG35512.1 - 6.2e-50 170.0 0.0 9.7e-50 169.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-III DegT_DnrJ_EryC1 PF01041.17 OAG35512.1 - 0.049 12.9 0.1 0.094 12.0 0.1 1.4 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family PhyH PF05721.13 OAG35513.1 - 2.1e-30 106.6 0.0 2.6e-30 106.3 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Arteri_env PF01606.16 OAG35513.1 - 0.025 14.4 0.0 0.041 13.8 0.0 1.2 1 0 0 1 1 1 0 Arterivirus envelope protein PPDFL PF15060.6 OAG35513.1 - 0.053 14.1 0.0 0.42 11.2 0.0 2.3 2 0 0 2 2 2 0 Differentiation and proliferation regulator DUF1349 PF07081.11 OAG35514.1 - 8.4e-11 41.9 0.0 1e-10 41.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) FAD_binding_4 PF01565.23 OAG35515.1 - 6.7e-27 93.9 0.9 6.7e-27 93.9 0.9 1.6 2 0 0 2 2 2 1 FAD binding domain AA_permease_2 PF13520.6 OAG35516.1 - 7e-40 137.1 45.9 8.6e-40 136.9 45.9 1.0 1 0 0 1 1 1 1 Amino acid permease FMN_dh PF01070.18 OAG35517.1 - 2e-108 362.5 0.0 2.7e-108 362.1 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 OAG35517.1 - 4.4e-15 55.6 0.0 8.3e-15 54.7 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 OAG35517.1 - 0.00019 20.7 0.1 0.00038 19.7 0.1 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 OAG35517.1 - 0.00027 20.0 0.0 0.00048 19.2 0.0 1.3 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.14 OAG35517.1 - 0.001 18.4 0.2 1.4 8.2 0.0 2.3 1 1 0 2 2 2 2 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 OAG35517.1 - 0.042 13.3 0.2 0.94 8.9 0.1 2.5 2 1 1 3 3 3 0 Histidine biosynthesis protein Pyridoxal_deC PF00282.19 OAG35518.1 - 2.4e-78 263.4 0.0 3.2e-78 263.1 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Cytochrom_D1 PF02239.16 OAG35520.1 - 0.00023 19.8 0.0 0.01 14.4 0.0 2.7 1 1 2 3 3 3 2 Cytochrome D1 heme domain Lactonase PF10282.9 OAG35520.1 - 0.00099 18.5 0.0 3 7.0 0.0 2.9 2 1 0 2 2 2 2 Lactonase, 7-bladed beta-propeller FlaG PF03646.15 OAG35520.1 - 0.013 15.6 0.3 10 6.4 0.1 3.3 3 0 0 3 3 3 0 FlaG protein MRJP PF03022.16 OAG35520.1 - 0.013 14.8 0.0 5 6.4 0.0 3.2 3 0 0 3 3 3 0 Major royal jelly protein PQQ_3 PF13570.6 OAG35520.1 - 0.034 14.6 0.4 15 6.2 0.1 3.5 4 0 0 4 4 4 0 PQQ-like domain F-box-like PF12937.7 OAG35521.1 - 0.00031 20.6 1.6 0.00052 19.9 0.6 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 OAG35521.1 - 0.0012 18.6 0.7 0.0048 16.7 0.0 2.5 2 1 0 2 2 2 1 F-box domain F-box-like_2 PF13013.6 OAG35521.1 - 0.068 13.1 0.7 0.25 11.3 0.1 2.3 3 0 0 3 3 3 0 F-box-like domain APOBEC1 PF18769.1 OAG35521.1 - 0.078 13.2 0.1 0.16 12.3 0.1 1.4 1 0 0 1 1 1 0 APOBEC1 DnaJ PF00226.31 OAG35522.1 - 1.1e-18 67.1 0.0 2.3e-18 66.1 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain NAM-associated PF14303.6 OAG35522.1 - 0.0026 18.5 3.6 0.16 12.7 0.0 2.4 1 1 1 2 2 2 1 No apical meristem-associated C-terminal domain Kisspeptin PF15152.6 OAG35522.1 - 1.6 9.6 5.6 0.43 11.4 0.9 2.4 2 0 0 2 2 2 0 Kisspeptin CP2 PF04516.15 OAG35523.1 - 1.1e-74 250.7 0.0 1.6e-74 250.1 0.0 1.2 1 0 0 1 1 1 1 CP2 transcription factor Tektin PF03148.14 OAG35523.1 - 0.12 11.1 0.0 0.18 10.5 0.0 1.2 1 0 0 1 1 1 0 Tektin family DUF1154 PF06631.11 OAG35525.1 - 0.39 10.8 5.0 0.97 9.5 2.8 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1154) DFP PF04127.15 OAG35526.1 - 3.1e-17 63.0 0.0 1.8e-09 37.7 0.0 2.2 2 0 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein RTA1 PF04479.13 OAG35527.1 - 1.9e-36 125.6 5.1 2.6e-36 125.2 5.1 1.2 1 0 0 1 1 1 1 RTA1 like protein DUF308 PF03729.13 OAG35527.1 - 0.047 14.0 2.6 0.047 14.0 2.6 2.9 2 1 0 2 2 2 0 Short repeat of unknown function (DUF308) DUF3377 PF11857.8 OAG35527.1 - 0.14 12.1 0.1 0.28 11.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) AAA_22 PF13401.6 OAG35528.1 - 0.001 19.3 0.0 1.1 9.5 0.0 3.3 4 0 0 4 4 4 2 AAA domain YebO PF13974.6 OAG35529.1 - 0.042 13.9 0.1 0.059 13.4 0.1 1.3 1 0 0 1 1 1 0 YebO-like protein Cu-oxidase_3 PF07732.15 OAG35530.1 - 3.1e-39 133.7 2.6 2.3e-36 124.4 0.1 3.2 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 OAG35530.1 - 2.7e-33 114.6 5.1 1.8e-25 89.3 0.3 3.4 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 OAG35530.1 - 6.2e-20 71.9 0.0 6.5e-18 65.4 0.0 3.3 3 1 0 3 3 3 1 Multicopper oxidase Lectin_like PF18560.1 OAG35530.1 - 0.019 15.2 0.0 0.039 14.1 0.0 1.4 1 0 0 1 1 1 0 Lectin like domain GFO_IDH_MocA PF01408.22 OAG35531.1 - 1.2e-09 39.0 0.1 4e-09 37.3 0.1 1.9 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold CoA_binding_2 PF13380.6 OAG35531.1 - 0.048 14.1 0.0 0.097 13.2 0.0 1.4 1 0 0 1 1 1 0 CoA binding domain Pyr_excise PF03013.14 OAG35531.1 - 0.22 11.5 0.3 3.1 7.8 0.1 2.2 2 0 0 2 2 2 0 Pyrimidine dimer DNA glycosylase Cation_ATPase_C PF00689.21 OAG35533.1 - 2.1e-47 161.2 6.8 2.1e-47 161.2 6.8 2.0 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 OAG35533.1 - 1.5e-36 125.6 0.1 1.5e-36 125.6 0.1 2.7 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 OAG35533.1 - 6.6e-19 69.0 0.2 2.5e-18 67.1 0.2 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 OAG35533.1 - 7.7e-19 67.6 0.0 1.4e-18 66.7 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 OAG35533.1 - 6.9e-10 38.5 0.0 2.6e-09 36.6 0.0 2.0 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 OAG35533.1 - 0.00068 19.5 0.1 0.0053 16.5 0.0 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Ferlin_C PF16165.5 OAG35533.1 - 0.15 12.0 0.1 0.48 10.4 0.1 1.8 1 0 0 1 1 1 0 Ferlin C-terminus MFS_1 PF07690.16 OAG35534.1 - 5.6e-49 167.0 19.6 5.6e-49 167.0 19.6 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG35534.1 - 3.1e-11 42.8 5.6 3.1e-11 42.8 5.6 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 OAG35534.1 - 0.28 9.5 7.8 0.0065 14.9 1.4 1.4 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 OAG35534.1 - 2.1 6.5 7.0 4.9 5.3 1.6 2.6 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family MoaE PF02391.17 OAG35535.1 - 4.7e-34 117.1 0.0 6e-34 116.7 0.0 1.1 1 0 0 1 1 1 1 MoaE protein SCO1-SenC PF02630.14 OAG35536.1 - 2e-44 150.7 0.0 2.9e-44 150.2 0.0 1.2 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 OAG35536.1 - 1.6e-05 24.8 0.0 2.5e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 OAG35536.1 - 0.0071 16.6 0.0 0.012 16.0 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Amidohydro_1 PF01979.20 OAG35537.1 - 2.1e-15 56.9 1.1 6.2e-07 29.1 0.3 2.5 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 OAG35537.1 - 3.6e-09 36.6 4.8 0.0027 17.3 0.0 3.2 2 1 1 3 3 3 3 Amidohydrolase family Cyt-b5 PF00173.28 OAG35538.1 - 5.4e-13 48.9 0.0 8.1e-13 48.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FAA_hydrolase PF01557.18 OAG35539.1 - 1.9e-60 204.2 0.0 2.9e-60 203.6 0.0 1.3 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Abhydrolase_1 PF00561.20 OAG35539.1 - 1.6e-18 67.3 0.1 1.3e-12 48.0 0.2 2.5 1 1 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAG35539.1 - 2.3e-16 59.8 0.0 5.4e-16 58.6 0.0 1.6 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OAG35539.1 - 4.4e-14 53.6 0.4 4.4e-14 53.6 0.4 3.1 3 1 0 3 3 3 1 Alpha/beta hydrolase family Fungal_trans PF04082.18 OAG35539.1 - 1.9e-12 46.8 0.6 3.6e-12 45.9 0.6 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ser_hydrolase PF06821.13 OAG35539.1 - 0.0029 17.5 2.1 0.0033 17.3 0.1 2.0 2 1 0 2 2 2 1 Serine hydrolase Abhydrolase_4 PF08386.10 OAG35539.1 - 0.0029 17.7 0.1 0.0068 16.5 0.1 1.5 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_5 PF12695.7 OAG35539.1 - 0.0097 15.7 0.0 3.7 7.3 0.0 2.5 1 1 1 2 2 2 1 Alpha/beta hydrolase family Thioesterase PF00975.20 OAG35539.1 - 0.018 15.2 0.2 0.044 13.9 0.2 1.8 1 1 0 1 1 1 0 Thioesterase domain Esterase PF00756.20 OAG35539.1 - 0.026 14.2 0.1 0.047 13.3 0.1 1.3 1 0 0 1 1 1 0 Putative esterase Med11 PF10280.9 OAG35539.1 - 0.12 12.9 0.0 0.26 11.7 0.0 1.5 1 0 0 1 1 1 0 Mediator complex protein PGAP1 PF07819.13 OAG35539.1 - 0.15 11.7 0.0 2.3 7.9 0.0 2.3 2 0 0 2 2 2 0 PGAP1-like protein CCDC53 PF10152.9 OAG35539.1 - 0.43 11.0 7.8 4.8 7.6 0.1 2.4 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex DUF2076 PF09849.9 OAG35539.1 - 2.3 8.2 9.9 4.4 7.3 9.9 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) VIR_N PF15912.5 OAG35539.1 - 9.2 5.8 9.4 19 4.8 9.4 1.4 1 0 0 1 1 1 0 Virilizer, N-terminal RPE65 PF03055.15 OAG35540.1 - 2.4e-122 409.5 0.0 2.7e-122 409.3 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein PPI_Ypi1 PF07491.11 OAG35540.1 - 0.012 15.4 0.0 0.027 14.3 0.0 1.5 1 0 0 1 1 1 0 Protein phosphatase inhibitor SQS_PSY PF00494.19 OAG35541.1 - 1.4e-56 191.9 0.6 1.8e-56 191.5 0.6 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase Amino_oxidase PF01593.24 OAG35542.1 - 1.7e-23 83.7 0.0 3.5e-22 79.3 0.0 2.0 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OAG35542.1 - 9.7e-15 54.6 0.3 2.3e-14 53.4 0.3 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAG35542.1 - 7.5e-12 45.5 0.9 1e-10 41.7 1.0 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OAG35542.1 - 5.2e-09 35.7 0.2 1.8e-07 30.6 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 OAG35542.1 - 6.7e-09 35.4 0.0 2e-06 27.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAG35542.1 - 4e-07 29.1 0.3 8.2e-05 21.5 1.0 2.1 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.19 OAG35542.1 - 8e-05 22.0 0.2 0.00021 20.7 0.2 1.6 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 OAG35542.1 - 9.4e-05 21.8 0.2 0.00016 21.0 0.2 1.3 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 OAG35542.1 - 0.00012 21.6 1.6 0.0013 18.2 2.5 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 OAG35542.1 - 0.00035 19.9 0.5 0.00066 19.0 0.5 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAG35542.1 - 0.0027 18.2 0.5 0.043 14.4 0.4 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OAG35542.1 - 0.007 15.5 1.0 0.007 15.5 1.0 1.5 2 0 0 2 2 2 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 OAG35542.1 - 0.021 13.9 0.2 0.047 12.7 0.2 1.6 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 OAG35542.1 - 0.069 13.1 0.7 0.41 10.6 0.2 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Trp_halogenase PF04820.14 OAG35542.1 - 0.081 11.8 2.9 1 8.1 0.6 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Glu_dehyd_C PF16912.5 OAG35542.1 - 0.096 12.2 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus ApbA PF02558.16 OAG35542.1 - 0.12 12.0 0.4 0.3 10.7 0.4 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 OAG35542.1 - 0.2 11.5 0.4 0.34 10.8 0.4 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Bac_rhodopsin PF01036.18 OAG35543.1 - 5.4e-44 150.4 19.9 6.9e-44 150.1 19.9 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF1980 PF09323.10 OAG35543.1 - 6.8 6.6 5.8 1.2 9.0 2.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) LRR_4 PF12799.7 OAG35545.1 - 6.5e-10 39.1 9.1 2.3e-07 31.0 2.5 4.1 3 1 2 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OAG35545.1 - 1.5e-08 34.2 3.8 5.5e-08 32.5 3.8 2.0 1 0 0 1 1 1 1 Leucine rich repeat LRR_1 PF00560.33 OAG35545.1 - 0.021 15.3 6.0 9.2 7.3 0.3 4.3 4 0 0 4 4 4 0 Leucine Rich Repeat TctC PF03401.14 OAG35545.1 - 0.058 12.5 0.0 0.088 11.8 0.0 1.2 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter family receptor LRR_9 PF14580.6 OAG35545.1 - 0.087 12.3 1.1 0.15 11.6 0.2 1.7 2 0 0 2 2 2 0 Leucine-rich repeat zinc_ribbon_12 PF11331.8 OAG35545.1 - 0.4 10.5 1.3 6 6.8 0.2 2.6 2 0 0 2 2 2 0 Probable zinc-ribbon domain LRR_6 PF13516.6 OAG35545.1 - 3.2 8.0 6.9 21 5.5 0.2 3.4 3 0 0 3 3 3 0 Leucine Rich repeat Efg1 PF10153.9 OAG35547.1 - 3e-29 101.7 8.8 3e-29 101.7 8.8 2.1 2 0 0 2 2 2 1 rRNA-processing protein Efg1 PH_10 PF15411.6 OAG35547.1 - 0.85 9.9 4.0 1.6 9.0 3.3 1.7 1 1 0 1 1 1 0 Pleckstrin homology domain zinc_ribbon_16 PF17034.5 OAG35548.1 - 6.6e-06 26.3 0.1 1.5e-05 25.2 0.1 1.6 1 0 0 1 1 1 1 Zinc-ribbon like family WD40 PF00400.32 OAG35548.1 - 0.0014 19.4 0.2 19 6.3 0.2 4.4 3 0 0 3 3 3 2 WD domain, G-beta repeat DUF5413 PF17434.2 OAG35548.1 - 0.15 12.4 1.6 0.4 11.0 1.6 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5413) MAPEG PF01124.18 OAG35549.1 - 9.3e-13 48.2 1.6 1.3e-12 47.8 1.6 1.3 1 1 0 1 1 1 1 MAPEG family V-ATPase_H_N PF03224.14 OAG35549.1 - 0.26 10.5 0.0 0.38 10.0 0.0 1.1 1 0 0 1 1 1 0 V-ATPase subunit H SOAR PF16533.5 OAG35550.1 - 0.21 11.5 6.0 0.43 10.6 6.0 1.5 1 1 0 1 1 1 0 STIM1 Orai1-activating region Ureidogly_lyase PF04115.12 OAG35551.1 - 3.3e-09 36.8 0.0 2.3e-08 34.0 0.0 1.9 2 0 0 2 2 2 1 Ureidoglycolate lyase Fungal_trans PF04082.18 OAG35553.1 - 1.1e-23 83.7 0.3 2e-23 82.8 0.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG35553.1 - 8.1e-06 25.9 12.0 8.1e-06 25.9 12.0 2.8 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AGH PF17558.2 OAG35553.1 - 0.11 12.7 0.6 0.28 11.4 0.6 1.7 1 0 0 1 1 1 0 Androgenic gland hormone Fungal_trans PF04082.18 OAG35554.1 - 5.7e-13 48.5 0.2 1.7e-12 47.0 0.2 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain ADH_N PF08240.12 OAG35555.1 - 1.5e-18 66.7 0.2 2.6e-18 65.9 0.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG35555.1 - 6.6e-15 55.2 0.1 1.3e-14 54.3 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAG35555.1 - 0.0005 21.1 0.1 0.00087 20.3 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 OAG35555.1 - 0.08 12.4 0.1 0.16 11.4 0.1 1.5 1 0 0 1 1 1 0 short chain dehydrogenase SAM_MT PF04445.13 OAG35555.1 - 0.43 10.0 2.1 0.45 9.9 0.5 1.7 2 0 0 2 2 2 0 Putative SAM-dependent methyltransferase 2-Hacid_dh_C PF02826.19 OAG35556.1 - 2.1e-43 147.8 0.0 3.3e-43 147.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 OAG35556.1 - 2e-07 30.8 0.0 9.5e-07 28.6 0.0 1.9 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AOC_like PF18678.1 OAG35556.1 - 0.019 14.6 0.0 0.039 13.6 0.0 1.4 1 0 0 1 1 1 0 Allene oxide cyclase barrel like domain p450 PF00067.22 OAG35557.1 - 6.9e-54 183.3 0.0 7.8e-54 183.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 APH PF01636.23 OAG35558.1 - 8.5e-10 39.0 5.2 9e-10 38.9 0.6 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family DUF1679 PF07914.11 OAG35558.1 - 0.015 14.2 0.0 0.021 13.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) GH101_N PF17995.1 OAG35558.1 - 0.056 13.1 0.0 0.081 12.6 0.0 1.2 1 0 0 1 1 1 0 Endo-alpha-N-acetylgalactosaminidase N-terminal EcKinase PF02958.20 OAG35558.1 - 0.18 11.1 0.0 0.36 10.1 0.0 1.4 1 0 0 1 1 1 0 Ecdysteroid kinase XRN_M PF17846.1 OAG35559.1 - 8e-145 483.2 1.6 2.6e-144 481.5 0.0 2.3 2 1 0 2 2 2 1 Xrn1 helical domain XRN_N PF03159.18 OAG35559.1 - 1.3e-97 326.0 0.0 1.3e-97 326.0 0.0 1.6 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus zf-CCHC PF00098.23 OAG35559.1 - 0.0083 16.2 3.7 0.016 15.3 3.7 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 OAG35559.1 - 0.01 15.7 2.4 0.022 14.6 2.4 1.6 1 0 0 1 1 1 0 Zinc knuckle TetR_C_20 PF17925.1 OAG35559.1 - 0.089 13.1 0.0 0.23 11.8 0.0 1.6 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain AMP-binding PF00501.28 OAG35560.1 - 1.5e-88 297.2 0.0 1.9e-88 296.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG35560.1 - 2.9e-14 53.8 0.0 8.5e-14 52.3 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Uso1_p115_head PF04869.14 OAG35561.1 - 4.6e-100 334.8 0.0 8.9e-100 333.8 0.0 1.5 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.13 OAG35561.1 - 7.9e-19 68.3 34.9 7.9e-19 68.3 34.9 3.9 1 1 1 2 2 2 1 Uso1 / p115 like vesicle tethering protein, C terminal region Pox_A_type_inc PF04508.12 OAG35561.1 - 0.0021 17.8 0.2 0.0021 17.8 0.2 3.4 4 0 0 4 4 4 1 Viral A-type inclusion protein repeat Cnn_1N PF07989.11 OAG35561.1 - 0.014 15.5 9.6 0.014 15.5 9.6 4.8 1 1 3 4 4 4 0 Centrosomin N-terminal motif 1 Sugarporin_N PF11471.8 OAG35561.1 - 0.016 15.1 3.0 0.016 15.1 3.0 4.3 4 0 0 4 4 4 0 Maltoporin periplasmic N-terminal extension Atx10homo_assoc PF09759.9 OAG35561.1 - 0.022 14.8 4.5 2.5 8.2 0.0 4.4 5 0 0 5 5 5 0 Spinocerebellar ataxia type 10 protein domain HEAT PF02985.22 OAG35561.1 - 1.9 9.0 5.3 13 6.4 0.0 4.4 6 0 0 6 6 6 0 HEAT repeat Acetyltransf_11 PF13720.6 OAG35561.1 - 2.1 8.8 8.9 1.7 9.1 0.0 4.3 3 1 2 5 5 5 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 TFIIA PF03153.13 OAG35561.1 - 5 7.0 31.9 7.8 6.4 31.9 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NAD_binding_2 PF03446.15 OAG35562.1 - 3.8e-31 108.4 0.1 5.8e-31 107.8 0.1 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 OAG35562.1 - 1.2e-09 38.4 0.1 4.6e-09 36.6 0.1 1.9 1 1 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase OCD_Mu_crystall PF02423.15 OAG35562.1 - 1.3e-06 27.6 0.0 2.1e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family F420_oxidored PF03807.17 OAG35562.1 - 0.0016 18.9 0.0 0.004 17.7 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA PF01408.22 OAG35562.1 - 0.032 15.1 0.0 0.41 11.5 0.0 2.3 1 1 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold tRNA-synt_1 PF00133.22 OAG35563.1 - 5.3e-223 741.6 0.1 9.4e-223 740.8 0.1 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 OAG35563.1 - 2.7e-23 82.6 0.0 6.2e-22 78.2 0.0 2.6 3 0 0 3 3 3 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 OAG35563.1 - 7.3e-15 54.6 0.0 1.2e-05 24.2 0.0 3.9 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 OAG35563.1 - 0.00078 18.9 0.1 0.037 13.4 0.0 2.8 3 0 0 3 3 3 1 tRNA synthetases class I (C) catalytic domain zf-C2H2_aberr PF17017.5 OAG35564.1 - 0.0036 17.5 0.4 0.01 16.0 0.4 1.7 1 1 1 2 2 2 1 Aberrant zinc-finger zf-C2H2 PF00096.26 OAG35564.1 - 0.051 14.1 15.7 1.7 9.2 0.3 4.4 3 1 1 4 4 4 0 Zinc finger, C2H2 type CsbD PF05532.12 OAG35565.1 - 0.32 10.9 3.3 0.42 10.5 3.3 1.2 1 0 0 1 1 1 0 CsbD-like Pkinase PF00069.25 OAG35566.1 - 1.7e-69 234.2 0.0 2.2e-69 233.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG35566.1 - 1.1e-30 106.8 0.0 1.6e-30 106.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 OAG35566.1 - 1.1e-13 51.7 0.4 6.8e-13 49.1 0.4 2.5 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 OAG35566.1 - 2.1e-08 33.8 0.0 1.9e-07 30.7 0.0 2.0 1 1 1 2 2 2 1 Kinase-like C2 PF00168.30 OAG35566.1 - 2.6e-06 27.7 0.0 0.0018 18.6 0.0 2.7 2 0 0 2 2 2 2 C2 domain Haspin_kinase PF12330.8 OAG35566.1 - 0.00076 18.5 0.1 0.0018 17.3 0.1 1.6 1 1 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 OAG35566.1 - 0.0072 16.0 0.2 1.9 8.1 0.0 2.4 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 OAG35566.1 - 0.011 15.7 0.1 0.03 14.3 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 OAG35566.1 - 0.096 12.3 0.1 0.16 11.5 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Adeno_E3_15_3 PF03307.14 OAG35566.1 - 0.15 12.0 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 Adenovirus 15.3kD protein in E3 region Kdo PF06293.14 OAG35566.1 - 0.15 11.4 0.1 0.24 10.7 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CRC_subunit PF08624.10 OAG35567.1 - 4.7e-53 179.2 0.1 8.2e-53 178.5 0.1 1.4 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit Apt1 PF10351.9 OAG35567.1 - 4.4 6.1 6.0 4.7 6.0 0.2 2.1 2 0 0 2 2 2 0 Golgi-body localisation protein domain Cyclin PF08613.11 OAG35568.1 - 1.4e-11 45.0 0.0 1.9e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 OAG35568.1 - 1.8e-05 24.5 0.0 3e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain AAA PF00004.29 OAG35569.1 - 1.8e-40 138.4 0.0 3.9e-40 137.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 OAG35569.1 - 2.3e-18 65.9 0.3 4.4e-18 65.0 0.3 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 OAG35569.1 - 2.3e-09 36.9 0.1 5.6e-09 35.7 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 OAG35569.1 - 4.1e-05 23.6 1.0 0.00016 21.6 0.0 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OAG35569.1 - 0.00013 22.4 1.3 0.019 15.3 0.0 3.0 2 1 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 OAG35569.1 - 0.00024 20.9 0.0 0.00063 19.5 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain PhoH PF02562.16 OAG35569.1 - 0.0027 17.2 0.3 0.065 12.7 0.1 2.4 2 0 0 2 2 2 1 PhoH-like protein AAA_22 PF13401.6 OAG35569.1 - 0.0029 17.9 1.9 0.1 12.9 0.0 2.9 2 1 1 3 3 3 1 AAA domain AAA_2 PF07724.14 OAG35569.1 - 0.0033 17.6 2.2 0.0095 16.1 0.0 2.8 2 2 0 2 2 2 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 OAG35569.1 - 0.004 16.6 0.1 0.02 14.3 0.1 2.1 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 OAG35569.1 - 0.0051 16.0 1.2 0.018 14.2 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_33 PF13671.6 OAG35569.1 - 0.012 15.8 0.0 0.037 14.2 0.0 2.0 1 0 0 1 1 1 0 AAA domain JIP_LZII PF16471.5 OAG35569.1 - 0.017 15.3 5.0 0.054 13.7 5.0 1.8 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II IstB_IS21 PF01695.17 OAG35569.1 - 0.066 12.9 0.1 0.15 11.8 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_7 PF12775.7 OAG35569.1 - 0.15 11.6 0.3 0.45 10.0 0.0 2.0 2 1 0 2 2 2 0 P-loop containing dynein motor region AAA_11 PF13086.6 OAG35569.1 - 0.31 10.8 0.0 0.31 10.8 0.0 3.0 2 2 1 3 3 2 0 AAA domain CLZ PF16526.5 OAG35569.1 - 3 8.3 11.5 0.54 10.7 6.1 2.7 2 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Atg14 PF10186.9 OAG35569.1 - 8.8 5.3 12.1 14 4.7 12.1 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 HET PF06985.11 OAG35571.1 - 7.5e-23 81.5 0.0 1.3e-22 80.7 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MMR_HSR1 PF01926.23 OAG35571.1 - 4.6e-06 26.7 0.0 9.4e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OAG35571.1 - 0.0036 17.2 0.0 0.0071 16.3 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AIG1 PF04548.16 OAG35571.1 - 0.024 14.0 0.0 0.042 13.2 0.0 1.4 1 0 0 1 1 1 0 AIG1 family ABC_tran PF00005.27 OAG35571.1 - 0.046 14.2 0.0 0.12 12.9 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Dynamin_N PF00350.23 OAG35571.1 - 0.051 13.6 0.0 0.16 12.0 0.0 1.7 1 1 0 1 1 1 0 Dynamin family An_peroxidase PF03098.15 OAG35572.1 - 1.6e-33 116.1 0.9 1.2e-08 34.0 0.0 4.5 3 1 2 5 5 5 4 Animal haem peroxidase p450 PF00067.22 OAG35572.1 - 2.2e-09 36.6 0.0 1.8e-08 33.6 0.0 2.0 2 0 0 2 2 2 1 Cytochrome P450 MFS_1 PF07690.16 OAG35573.1 - 1.6e-32 112.8 52.5 2.9e-30 105.4 45.4 3.0 1 1 1 2 2 2 2 Major Facilitator Superfamily HET PF06985.11 OAG35574.1 - 9e-13 48.8 0.4 2e-09 37.9 0.0 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) adh_short PF00106.25 OAG35575.1 - 0.0001 21.8 0.0 0.0013 18.2 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase acVLRF1 PF18859.1 OAG35575.1 - 0.13 12.5 0.8 9.5 6.5 0.1 2.4 2 0 0 2 2 2 0 Actinobacteria/chloroflexi VLRF1 release factor Pkinase PF00069.25 OAG35577.1 - 2.5e-08 33.6 0.0 2.2e-06 27.3 0.0 2.4 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAG35577.1 - 4e-05 23.0 0.0 0.0013 18.1 0.0 2.7 3 0 0 3 3 3 1 Protein tyrosine kinase Glyco_hydro_72 PF03198.14 OAG35579.1 - 1.4e-91 307.1 0.3 2e-91 306.6 0.3 1.1 1 0 0 1 1 1 1 Glucanosyltransferase ABC2_membrane PF01061.24 OAG35580.1 - 4.2e-86 287.7 54.5 7.5e-44 149.7 16.6 3.1 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 OAG35580.1 - 7.8e-39 133.3 0.1 3e-20 73.1 0.0 2.7 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 OAG35580.1 - 1.6e-29 101.6 4.2 2.2e-25 88.4 0.1 2.9 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.6 OAG35580.1 - 1.3e-14 54.6 2.0 1.3e-14 54.6 2.0 3.0 3 1 0 3 3 1 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 OAG35580.1 - 2.2e-06 27.1 32.2 8.6e-06 25.1 12.3 2.8 3 0 0 3 3 3 2 ABC-2 family transporter protein AAA_18 PF13238.6 OAG35580.1 - 1.2e-05 25.8 0.0 0.00038 21.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OAG35580.1 - 2.6e-05 24.7 0.1 0.022 15.1 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 OAG35580.1 - 2.6e-05 24.2 0.4 0.00036 20.5 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_21 PF13304.6 OAG35580.1 - 3.4e-05 23.8 0.6 0.027 14.3 0.0 2.5 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 OAG35580.1 - 0.00093 18.9 0.7 0.54 10.0 0.2 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 OAG35580.1 - 0.0011 19.0 0.0 0.072 13.2 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_28 PF13521.6 OAG35580.1 - 0.0016 18.7 0.0 0.0055 17.0 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 OAG35580.1 - 0.0017 18.6 0.1 0.18 12.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 OAG35580.1 - 0.0022 18.1 0.0 0.06 13.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 OAG35580.1 - 0.005 16.4 0.3 0.16 11.5 0.1 2.6 2 1 0 2 2 2 1 AAA domain SMC_N PF02463.19 OAG35580.1 - 0.0065 15.9 0.5 0.054 12.9 0.0 2.5 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain NACHT PF05729.12 OAG35580.1 - 0.0083 16.1 0.3 0.51 10.2 0.2 2.4 2 0 0 2 2 2 1 NACHT domain AAA_24 PF13479.6 OAG35580.1 - 0.015 15.1 0.1 0.2 11.4 0.0 2.6 3 0 0 3 3 3 0 AAA domain FtsK_SpoIIIE PF01580.18 OAG35580.1 - 0.058 12.7 0.8 9.6 5.5 0.3 2.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family cobW PF02492.19 OAG35580.1 - 0.064 12.8 0.5 0.32 10.5 0.3 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.23 OAG35580.1 - 0.068 13.2 1.3 0.16 12.0 0.0 2.3 3 0 0 3 3 2 0 Dynamin family Septin PF00735.18 OAG35580.1 - 0.073 12.3 0.1 0.33 10.2 0.0 2.0 2 0 0 2 2 2 0 Septin T2SSE PF00437.20 OAG35580.1 - 0.1 11.6 0.3 1.4 7.9 0.2 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein NB-ARC PF00931.22 OAG35580.1 - 0.11 11.7 0.2 3.1 6.9 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_30 PF13604.6 OAG35580.1 - 0.36 10.5 3.6 5.9 6.6 0.4 2.7 3 0 0 3 3 3 0 AAA domain AAA_17 PF13207.6 OAG35580.1 - 0.68 10.4 4.4 7.4 7.0 0.1 3.5 4 0 0 4 4 3 0 AAA domain adh_short PF00106.25 OAG35581.1 - 1.6e-25 89.7 0.1 3.3e-24 85.5 0.1 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG35581.1 - 1.6e-16 60.5 0.4 2.7e-15 56.6 0.4 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 OAG35581.1 - 9.3e-06 25.3 0.0 1.3e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 OAG35581.1 - 1.1e-05 25.4 0.2 1.7e-05 24.8 0.2 1.3 1 0 0 1 1 1 1 KR domain DNA_processg_A PF02481.15 OAG35581.1 - 0.046 13.0 0.0 0.074 12.3 0.0 1.3 1 0 0 1 1 1 0 DNA recombination-mediator protein A GDP_Man_Dehyd PF16363.5 OAG35581.1 - 0.077 12.4 0.2 0.15 11.4 0.2 1.5 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 OAG35581.1 - 0.14 11.3 0.4 0.26 10.3 0.4 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain adh_short PF00106.25 OAG35582.1 - 1.3e-28 99.9 1.8 3.7e-16 59.2 0.1 3.1 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAG35582.1 - 2e-22 79.9 0.2 3.5e-12 46.4 0.0 2.2 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG35582.1 - 0.005 16.8 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 KR domain Methyltransf_31 PF13847.6 OAG35582.1 - 0.025 14.4 0.0 0.045 13.5 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain DUF4990 PF16380.5 OAG35582.1 - 0.08 13.1 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function ETF_QO PF05187.13 OAG35583.1 - 2.5e-25 88.6 0.0 4.2e-25 87.9 0.0 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S NAD_binding_8 PF13450.6 OAG35583.1 - 1.1e-07 32.0 0.0 3.5e-07 30.4 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAG35583.1 - 1.6e-07 31.2 1.0 0.00053 19.7 0.4 2.3 1 1 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.17 OAG35583.1 - 6e-06 25.7 0.0 0.00043 19.6 0.1 2.1 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 OAG35583.1 - 3.1e-05 23.2 1.3 0.0025 17.0 1.0 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 OAG35583.1 - 6.7e-05 22.3 0.1 0.00016 21.0 0.1 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 OAG35583.1 - 0.00023 20.5 0.4 0.00042 19.7 0.4 1.6 1 1 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 OAG35583.1 - 0.00045 19.0 0.4 0.00072 18.4 0.4 1.3 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_9 PF13454.6 OAG35583.1 - 0.00077 19.5 0.1 0.0027 17.7 0.1 1.8 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 OAG35583.1 - 0.0021 17.4 0.3 0.0036 16.6 0.3 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAG35583.1 - 0.0046 17.5 0.4 3 8.4 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 OAG35583.1 - 0.012 14.9 0.0 0.049 12.9 0.0 1.8 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 OAG35583.1 - 0.061 12.7 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 OAG35583.1 - 0.062 12.3 0.3 0.095 11.7 0.3 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 OAG35583.1 - 0.14 11.4 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain K_oxygenase PF13434.6 OAG35583.1 - 0.15 11.2 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.22 OAG35583.1 - 0.17 11.0 0.1 0.3 10.1 0.1 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A TBP PF00352.21 OAG35584.1 - 1.2e-67 223.8 0.0 7.5e-33 112.3 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 OAG35584.1 - 0.00013 22.0 0.0 0.24 11.6 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) DUF4295 PF14128.6 OAG35584.1 - 0.046 13.5 0.1 0.26 11.2 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4295) DAO PF01266.24 OAG35585.1 - 3.1e-40 138.8 1.7 4e-40 138.5 1.7 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 OAG35585.1 - 1.2e-05 25.4 0.2 0.016 15.2 0.0 2.6 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 OAG35585.1 - 0.0001 21.6 0.0 0.28 10.4 0.0 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAG35585.1 - 0.00016 20.9 2.6 0.00066 18.9 2.6 2.0 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 OAG35585.1 - 0.0039 17.4 0.0 0.0095 16.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 OAG35585.1 - 0.023 13.7 0.0 0.15 11.0 0.0 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein GIDA PF01134.22 OAG35585.1 - 0.032 13.3 0.0 0.09 11.8 0.0 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A MCRA PF06100.11 OAG35585.1 - 0.066 12.0 0.0 0.085 11.6 0.0 1.1 1 0 0 1 1 1 0 MCRA family FAD_binding_3 PF01494.19 OAG35585.1 - 0.1 11.8 0.1 6 6.0 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain Sacchrp_dh_NADP PF03435.18 OAG35585.1 - 0.17 12.2 0.0 0.29 11.4 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Methyltransf_23 PF13489.6 OAG35586.1 - 7e-18 65.0 0.1 1.7e-12 47.5 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 OAG35586.1 - 3.3e-05 24.5 0.0 7.4e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG35586.1 - 0.0039 17.8 0.0 0.014 16.1 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain DUF3611 PF12263.8 OAG35586.1 - 0.078 12.9 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3611) AAA_23 PF13476.6 OAG35587.1 - 0.031 14.8 1.4 0.046 14.2 1.4 1.2 1 0 0 1 1 1 0 AAA domain Occludin_ELL PF07303.13 OAG35587.1 - 0.043 14.5 0.0 1.4 9.6 0.1 3.0 3 0 0 3 3 3 0 Occludin homology domain G_glu_transpept PF01019.21 OAG35588.1 - 2e-152 508.6 2.6 7.2e-152 506.7 2.6 1.7 1 1 0 1 1 1 1 Gamma-glutamyltranspeptidase MFS_1 PF07690.16 OAG35588.1 - 1.2e-49 169.1 38.3 1.2e-49 169.1 38.3 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG35588.1 - 1.5e-08 34.0 10.9 1.5e-08 34.0 10.9 2.5 1 1 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 OAG35588.1 - 2.2e-05 24.0 9.0 2.2e-05 24.0 9.0 2.4 1 1 1 2 2 2 1 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 OAG35588.1 - 2.7 6.2 9.4 1.3 7.2 6.3 2.0 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family AMP-binding PF00501.28 OAG35589.1 - 6.9e-73 245.6 0.0 9e-73 245.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG35589.1 - 1.2e-10 42.3 0.1 2.5e-10 41.2 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain HATPase_c PF02518.26 OAG35590.1 - 3.5e-19 69.4 0.0 6.7e-19 68.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 OAG35590.1 - 7.4e-18 64.8 0.1 3.5e-17 62.6 0.1 2.2 1 1 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 OAG35590.1 - 8.4e-06 25.7 0.0 2.1e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain tRNA-synt_1g PF09334.11 OAG35591.1 - 6.1e-91 305.1 1.1 2.9e-89 299.6 1.1 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 OAG35591.1 - 4.8e-17 61.5 4.6 4.3e-09 35.2 0.1 3.4 2 2 1 3 3 3 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 OAG35591.1 - 7.5e-10 38.6 0.1 3.3e-05 23.4 0.1 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.13 OAG35591.1 - 0.085 12.8 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 Anticodon-binding domain of tRNA Aa_trans PF01490.18 OAG35592.1 - 2e-85 287.0 31.5 2.4e-85 286.7 31.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Adeno_GP19K PF04881.13 OAG35592.1 - 0.1 12.6 0.3 0.35 10.9 0.3 1.9 1 0 0 1 1 1 0 Adenovirus GP19K YpmT PF17431.2 OAG35592.1 - 0.96 9.5 4.3 2 8.5 1.0 2.8 2 0 0 2 2 2 0 Uncharacterized YmpT-like AA_permease PF00324.21 OAG35593.1 - 5.9e-55 186.7 32.2 7.8e-55 186.3 32.2 1.1 1 0 0 1 1 1 1 Amino acid permease SLC12 PF03522.15 OAG35593.1 - 1.6e-22 80.2 13.3 8.3e-11 41.6 0.0 4.1 4 0 0 4 4 4 3 Solute carrier family 12 Sigma70_ner PF04546.13 OAG35593.1 - 0.072 13.0 1.8 0.12 12.3 1.8 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region SpoIIIAH PF12685.7 OAG35593.1 - 0.39 10.5 4.9 0.81 9.5 4.9 1.5 1 0 0 1 1 1 0 SpoIIIAH-like protein Jagunal PF07086.12 OAG35593.1 - 0.52 10.4 2.9 0.69 10.0 0.3 2.3 2 1 0 2 2 2 0 Jagunal, ER re-organisation during oogenesis RR_TM4-6 PF06459.12 OAG35593.1 - 1.6 8.5 4.0 3.1 7.6 4.0 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GREB1 PF15782.5 OAG35593.1 - 2.3 5.2 4.4 3.1 4.8 4.4 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Nop14 PF04147.12 OAG35593.1 - 5.3 5.1 15.3 7.3 4.7 15.3 1.1 1 0 0 1 1 1 0 Nop14-like family Ribosomal_S13 PF00416.22 OAG35594.1 - 2.5e-18 66.7 0.3 9.2e-16 58.4 0.3 2.0 1 1 0 1 1 1 1 Ribosomal protein S13/S18 Pro_isomerase PF00160.21 OAG35595.1 - 3.9e-49 166.9 0.2 5.8e-49 166.4 0.2 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DEAD PF00270.29 OAG35596.1 - 2.9e-48 163.9 0.0 8.8e-48 162.4 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAG35596.1 - 5.1e-32 110.5 0.0 1.1e-31 109.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG35596.1 - 0.00054 20.0 0.0 0.0009 19.3 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 OAG35596.1 - 0.051 12.9 0.0 0.087 12.2 0.0 1.2 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Aldo_ket_red PF00248.21 OAG35597.1 - 1.3e-72 244.5 0.1 1.7e-72 244.1 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family UPF0154 PF03672.13 OAG35597.1 - 0.14 12.2 0.1 0.29 11.2 0.1 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) Lipase PF00151.19 OAG35598.1 - 0.42 9.9 1.8 0.64 9.3 1.8 1.2 1 0 0 1 1 1 0 Lipase Evr1_Alr PF04777.13 OAG35599.1 - 1.5e-24 86.3 0.2 3.3e-24 85.3 0.1 1.6 1 1 1 2 2 2 1 Erv1 / Alr family APOBEC4 PF18775.1 OAG35599.1 - 0.097 12.8 0.2 0.17 12.0 0.2 1.4 1 0 0 1 1 1 0 APOBEC4 SNAD4 PF18750.1 OAG35599.1 - 0.13 12.4 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC1 PF18769.1 OAG35599.1 - 0.14 12.4 0.1 0.41 10.9 0.1 1.7 1 1 0 1 1 1 0 APOBEC1 FAD_SOX PF18371.1 OAG35599.1 - 0.19 12.1 0.0 0.29 11.5 0.0 1.3 1 0 0 1 1 1 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase Aminotran_4 PF01063.19 OAG35600.1 - 2e-25 90.0 0.0 2.5e-25 89.7 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV Tropomyosin_1 PF12718.7 OAG35602.1 - 4.4e-52 176.1 35.1 5.7e-52 175.7 35.1 1.1 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.20 OAG35602.1 - 1.2e-08 34.7 34.4 0.00019 20.9 17.1 2.5 1 1 1 2 2 2 2 Tropomyosin Myosin_tail_1 PF01576.19 OAG35602.1 - 2.2e-05 22.5 30.3 2.5e-05 22.3 30.3 1.0 1 0 0 1 1 1 1 Myosin tail KLRAQ PF10205.9 OAG35602.1 - 0.00062 20.0 13.4 0.00062 20.0 13.4 2.7 1 1 1 2 2 2 1 Predicted coiled-coil domain-containing protein Spc7 PF08317.11 OAG35602.1 - 0.00086 18.3 36.7 0.009 14.9 17.3 2.0 1 1 1 2 2 2 2 Spc7 kinetochore protein DUF1664 PF07889.12 OAG35602.1 - 0.0013 18.8 16.0 0.094 12.8 3.6 2.4 2 1 0 2 2 2 2 Protein of unknown function (DUF1664) DUF4200 PF13863.6 OAG35602.1 - 0.0019 18.6 37.7 0.18 12.2 12.8 2.5 1 1 1 2 2 2 2 Domain of unknown function (DUF4200) Taxilin PF09728.9 OAG35602.1 - 0.0028 16.9 31.5 0.042 13.0 16.7 2.1 1 1 1 2 2 2 2 Myosin-like coiled-coil protein DUF3450 PF11932.8 OAG35602.1 - 0.0047 16.3 31.5 0.055 12.8 14.3 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3450) Lebercilin PF15619.6 OAG35602.1 - 0.0048 16.6 36.5 0.053 13.2 21.9 2.2 1 1 1 2 2 2 2 Ciliary protein causing Leber congenital amaurosis disease DUF812 PF05667.11 OAG35602.1 - 0.012 14.5 28.4 0.015 14.2 28.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) GAS PF13851.6 OAG35602.1 - 0.013 14.9 34.8 19 4.6 33.2 2.4 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding ADIP PF11559.8 OAG35602.1 - 0.013 15.5 33.1 0.079 13.0 19.9 2.6 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding ERM PF00769.19 OAG35602.1 - 0.016 15.0 40.8 0.031 14.1 19.4 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family ATG16 PF08614.11 OAG35602.1 - 0.017 15.4 35.5 0.47 10.7 17.9 2.0 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF724 PF05266.14 OAG35602.1 - 0.019 14.8 27.0 0.043 13.6 11.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Filament PF00038.21 OAG35602.1 - 0.037 13.6 29.7 0.58 9.7 12.8 2.0 1 1 1 2 2 2 0 Intermediate filament protein BLOC1_2 PF10046.9 OAG35602.1 - 0.047 14.0 26.2 0.058 13.7 1.8 3.4 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Jnk-SapK_ap_N PF09744.9 OAG35602.1 - 0.077 13.2 36.4 0.026 14.7 22.7 2.4 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 TMF_DNA_bd PF12329.8 OAG35602.1 - 0.081 12.9 40.8 1.7 8.7 4.8 3.4 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding CALCOCO1 PF07888.11 OAG35602.1 - 0.098 11.5 33.0 0.084 11.7 8.5 2.1 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like FlaC_arch PF05377.11 OAG35602.1 - 0.1 13.0 23.5 0.18 12.2 3.0 4.4 2 2 2 4 4 4 0 Flagella accessory protein C (FlaC) AAA_13 PF13166.6 OAG35602.1 - 0.13 10.9 22.8 0.19 10.3 22.8 1.3 1 0 0 1 1 1 0 AAA domain FUSC PF04632.12 OAG35602.1 - 0.13 10.8 9.9 0.17 10.4 9.9 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Laminin_II PF06009.12 OAG35602.1 - 0.14 12.1 21.7 0.057 13.4 7.0 2.2 1 1 1 2 2 2 0 Laminin Domain II Leu_zip PF15294.6 OAG35602.1 - 0.17 11.4 24.0 0.21 11.1 24.0 1.1 1 0 0 1 1 1 0 Leucine zipper APG6_N PF17675.1 OAG35602.1 - 0.18 12.3 43.7 1.1 9.8 21.8 2.5 1 1 1 2 2 2 0 Apg6 coiled-coil region Transketolase_N PF00456.21 OAG35602.1 - 0.2 10.6 6.8 0.26 10.2 6.8 1.1 1 0 0 1 1 1 0 Transketolase, thiamine diphosphate binding domain DUF5595 PF18077.1 OAG35602.1 - 0.2 11.7 22.5 1.8 8.7 6.6 3.6 3 1 0 3 3 3 0 Domain of unknown function (DUF5595) Dynamitin PF04912.14 OAG35602.1 - 0.28 10.4 27.7 3.6 6.8 27.7 2.3 1 1 0 1 1 1 0 Dynamitin KASH_CCD PF14662.6 OAG35602.1 - 0.29 11.0 33.7 0.66 9.8 32.4 2.1 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH CENP-F_leu_zip PF10473.9 OAG35602.1 - 0.29 11.2 36.3 13 5.8 36.7 2.6 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3452 PF11934.8 OAG35602.1 - 0.29 10.7 4.2 10 5.7 0.1 3.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3452) TPR_MLP1_2 PF07926.12 OAG35602.1 - 0.31 11.1 41.9 0.9 9.6 13.8 3.0 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein TMF_TATA_bd PF12325.8 OAG35602.1 - 0.45 10.7 29.1 5.5 7.3 19.1 2.7 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Cortex-I_coil PF09304.10 OAG35602.1 - 0.47 10.7 26.2 1.7 8.9 9.1 3.1 1 1 1 3 3 3 0 Cortexillin I, coiled coil EzrA PF06160.12 OAG35602.1 - 0.49 8.5 26.5 0.1 10.7 7.5 2.3 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA Fez1 PF06818.15 OAG35602.1 - 0.5 10.8 29.4 0.66 10.4 28.6 1.4 1 1 0 1 1 1 0 Fez1 BST2 PF16716.5 OAG35602.1 - 0.58 10.8 33.6 0.051 14.1 8.0 3.6 1 1 2 3 3 2 0 Bone marrow stromal antigen 2 FAM76 PF16046.5 OAG35602.1 - 0.63 9.3 25.2 5.1 6.4 25.2 1.8 1 1 0 1 1 1 0 FAM76 protein Uso1_p115_C PF04871.13 OAG35602.1 - 0.66 10.4 38.9 2.2 8.7 18.4 2.1 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region HMMR_N PF15905.5 OAG35602.1 - 0.67 9.4 34.4 1 8.8 34.4 1.3 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal MCPsignal PF00015.21 OAG35602.1 - 0.69 9.7 11.8 0.038 13.8 3.4 2.0 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Rab5-bind PF09311.11 OAG35602.1 - 0.71 9.2 28.9 0.13 11.7 12.1 2.1 1 1 1 2 2 2 0 Rabaptin-like protein MAD PF05557.13 OAG35602.1 - 0.75 8.1 33.0 1.4 7.2 33.0 1.4 1 1 0 1 1 1 0 Mitotic checkpoint protein TANGO2 PF05742.12 OAG35602.1 - 0.79 9.7 8.9 1.4 8.9 8.3 1.7 1 1 0 1 1 1 0 Transport and Golgi organisation 2 TACC_C PF05010.14 OAG35602.1 - 1.1 9.0 29.5 2 8.2 17.4 2.5 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal WXG100 PF06013.12 OAG35602.1 - 1.2 9.4 20.7 0.48 10.7 0.9 3.6 2 1 1 3 3 3 0 Proteins of 100 residues with WXG DUF4201 PF13870.6 OAG35602.1 - 1.5 8.6 29.3 1.6 8.5 8.4 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) HOOK PF05622.12 OAG35602.1 - 1.5 6.9 31.5 5.3 5.1 31.5 1.8 1 1 0 1 1 1 0 HOOK protein bZIP_1 PF00170.21 OAG35602.1 - 2.1 8.5 35.1 11 6.3 2.3 4.5 2 1 2 4 4 4 0 bZIP transcription factor Lectin_N PF03954.14 OAG35602.1 - 2.3 8.0 19.9 5.7 6.7 3.8 3.1 1 1 1 3 3 3 0 Hepatic lectin, N-terminal domain CENP-H PF05837.12 OAG35602.1 - 2.6 8.5 29.4 3.6 8.0 14.5 2.8 1 1 1 2 2 2 0 Centromere protein H (CENP-H) BRE1 PF08647.11 OAG35602.1 - 2.6 8.2 36.2 7.9 6.6 8.2 3.0 1 1 2 3 3 3 0 BRE1 E3 ubiquitin ligase NPV_P10 PF05531.12 OAG35602.1 - 3 8.4 13.3 2.3 8.7 0.1 3.3 1 1 1 2 2 1 0 Nucleopolyhedrovirus P10 protein Borrelia_P83 PF05262.11 OAG35602.1 - 3.2 6.2 27.5 4 5.8 27.5 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF3584 PF12128.8 OAG35602.1 - 3.2 5.1 32.9 5.8 4.3 32.9 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) DUF3958 PF13125.6 OAG35602.1 - 3.2 8.0 29.4 0.12 12.5 1.2 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF3958) Fib_alpha PF08702.10 OAG35602.1 - 3.4 7.8 21.2 3.3 7.9 7.4 2.6 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF4407 PF14362.6 OAG35602.1 - 4 6.7 27.4 69 2.6 27.7 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) PI3K_P85_iSH2 PF16454.5 OAG35602.1 - 4.6 6.8 29.8 11 5.6 2.2 2.7 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Seryl_tRNA_N PF02403.22 OAG35602.1 - 5 7.4 31.2 8.3 6.7 1.4 3.1 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain ZapB PF06005.12 OAG35602.1 - 5.5 7.5 43.7 4.2 7.9 2.2 4.1 1 1 2 3 3 3 0 Cell division protein ZapB DUF4472 PF14739.6 OAG35602.1 - 5.8 7.7 29.9 17 6.2 9.5 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4472) Rootletin PF15035.6 OAG35602.1 - 6 6.8 34.1 7.3 6.6 17.0 2.0 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion UPF0242 PF06785.11 OAG35602.1 - 6 6.9 35.4 7.9 6.5 14.8 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Ax_dynein_light PF10211.9 OAG35602.1 - 6.1 6.7 35.3 3.6 7.5 6.2 3.5 1 1 1 2 2 1 0 Axonemal dynein light chain DUF948 PF06103.11 OAG35602.1 - 6.1 7.2 14.2 50 4.3 3.3 3.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) HAUS6_N PF14661.6 OAG35602.1 - 7 6.2 27.1 0.46 10.0 8.5 2.7 1 1 1 2 2 1 0 HAUS augmin-like complex subunit 6 N-terminus Occludin_ELL PF07303.13 OAG35602.1 - 7.3 7.4 22.2 12 6.7 1.5 3.3 1 1 3 4 4 4 0 Occludin homology domain EHN PF06441.12 OAG35602.1 - 7.4 7.0 12.4 0.82 10.1 4.3 2.5 1 1 1 2 2 2 0 Epoxide hydrolase N terminus Fungal_TACC PF12709.7 OAG35602.1 - 8.1 7.0 29.6 9.3 6.8 5.2 4.1 1 1 3 4 4 4 0 Fungal Transforming acidic coiled-coil (TACC) proteins SHE3 PF17078.5 OAG35602.1 - 8.4 6.0 27.2 91 2.7 27.2 2.2 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 CREPT PF16566.5 OAG35602.1 - 8.4 6.6 24.6 13 6.0 1.0 3.1 1 1 2 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour HemX PF04375.14 OAG35602.1 - 9 5.5 30.7 17 4.5 14.0 2.4 1 1 2 3 3 3 0 HemX, putative uroporphyrinogen-III C-methyltransferase FapA PF03961.13 OAG35602.1 - 9.1 4.8 27.5 0.51 8.9 9.9 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A V_ATPase_I PF01496.19 OAG35602.1 - 9.4 4.0 24.3 0.33 8.8 9.8 2.0 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Nop25 PF09805.9 OAG35603.1 - 8.8e-41 139.6 12.6 8.8e-41 139.6 12.6 2.4 3 0 0 3 3 3 1 Nucleolar protein 12 (25kDa) LSM PF01423.22 OAG35604.1 - 2.6e-15 55.8 0.0 3.3e-15 55.5 0.0 1.1 1 0 0 1 1 1 1 LSM domain Ribosomal_L5_C PF00673.21 OAG35605.1 - 5.5e-22 77.8 0.0 8.1e-22 77.2 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 OAG35605.1 - 2.6e-20 72.5 0.0 8.9e-20 70.8 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L5 LYRIC PF15686.5 OAG35606.1 - 0.022 14.4 1.4 0.035 13.7 1.4 1.2 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family DUF2207 PF09972.9 OAG35606.1 - 0.15 10.8 0.3 0.3 9.8 0.3 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Ctr PF04145.15 OAG35606.1 - 1.2 9.7 3.8 11 6.6 3.8 2.5 1 1 0 1 1 1 0 Ctr copper transporter family Cep57_MT_bd PF06657.13 OAG35607.1 - 0.00011 22.6 0.4 0.00039 20.8 0.0 2.2 2 0 0 2 2 2 1 Centrosome microtubule-binding domain of Cep57 FliD_C PF07195.12 OAG35607.1 - 0.024 14.1 1.4 0.42 10.0 0.1 2.2 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus TetR_C_20 PF17925.1 OAG35607.1 - 0.48 10.8 2.9 29 5.0 0.3 3.1 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain eIF2A PF08662.11 OAG35608.1 - 3.6e-37 128.1 4.2 4e-33 115.0 1.6 3.9 3 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.22 OAG35608.1 - 1.1e-06 28.4 0.0 2.4e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.32 OAG35608.1 - 0.18 12.7 1.7 61 4.7 0.1 4.4 5 0 0 5 5 5 0 WD domain, G-beta repeat Metal_resist PF13801.6 OAG35608.1 - 0.24 11.6 0.7 0.46 10.7 0.1 1.8 2 0 0 2 2 2 0 Heavy-metal resistance SWIB PF02201.18 OAG35609.1 - 5.6e-28 96.6 0.2 1e-27 95.8 0.2 1.5 1 0 0 1 1 1 1 SWIB/MDM2 domain DEK_C PF08766.11 OAG35609.1 - 6.6e-12 45.2 0.4 1.3e-11 44.2 0.4 1.4 1 0 0 1 1 1 1 DEK C terminal domain TMA7 PF09072.10 OAG35609.1 - 1.8 9.4 12.5 9 7.2 1.6 2.4 2 0 0 2 2 2 0 Translation machinery associated TMA7 Cdc6_C PF09079.11 OAG35611.1 - 0.54 10.3 2.8 3.7 7.6 0.4 2.4 1 1 1 2 2 2 0 CDC6, C terminal winged helix domain T3SS_basalb_I PF17001.5 OAG35611.1 - 1.2 9.8 5.2 3.3 8.4 0.1 2.8 3 0 0 3 3 3 0 Type III secretion basal body protein I, YscI, HrpB, PscI MFS_1 PF07690.16 OAG35612.1 - 6.6e-34 117.4 15.7 8.2e-34 117.1 15.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2303 PF10065.9 OAG35612.1 - 0.21 10.7 0.1 0.32 10.1 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2303) Peptidase_C48 PF02902.19 OAG35613.1 - 1.1e-14 54.9 0.0 1.9e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain RhoGEF PF00621.20 OAG35614.1 - 7.6e-35 120.8 0.1 1.7e-34 119.6 0.1 1.7 1 0 0 1 1 1 1 RhoGEF domain Telomerase_RBD PF12009.8 OAG35615.1 - 8.9e-45 152.1 0.8 2.6e-44 150.6 0.8 1.8 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.27 OAG35615.1 - 8.2e-11 41.8 0.0 1.7e-06 27.7 0.0 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RabGAP-TBC PF00566.18 OAG35616.1 - 7.4e-25 87.9 0.0 1.3e-24 87.1 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SBE2 PF17076.5 OAG35616.1 - 2.5e-07 29.3 2.4 6.4e-07 28.0 2.4 1.6 1 1 1 2 2 2 1 SBE2, cell-wall formation Upf2 PF04050.14 OAG35616.1 - 0.21 12.3 2.2 0.22 12.2 0.6 1.9 2 0 0 2 2 2 0 Up-frameshift suppressor 2 PGBA_C PF15437.6 OAG35616.1 - 6.1 7.3 7.8 4.2 7.8 0.3 2.6 2 0 0 2 2 2 0 Plasminogen-binding protein pgbA C-terminal FMN_dh PF01070.18 OAG35617.1 - 2.2e-108 362.4 0.0 2.7e-108 362.1 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 OAG35617.1 - 2.8e-18 65.8 0.0 5.2e-18 65.0 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 OAG35617.1 - 0.00022 20.5 0.1 0.00037 19.7 0.1 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 OAG35617.1 - 0.0011 18.0 0.9 0.0082 15.2 0.9 2.1 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 OAG35617.1 - 0.0023 17.4 0.1 0.0036 16.7 0.1 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase NAD_binding_10 PF13460.6 OAG35618.1 - 0.062 13.2 0.0 0.19 11.6 0.0 1.9 1 1 0 1 1 1 0 NAD(P)H-binding CAP PF00188.26 OAG35619.1 - 7.8e-16 59.1 2.0 3.7e-15 56.9 2.0 1.9 1 1 0 1 1 1 1 Cysteine-rich secretory protein family Radial_spoke PF04712.12 OAG35620.1 - 0.091 11.7 4.2 0.12 11.3 4.2 1.2 1 0 0 1 1 1 0 Radial spokehead-like protein DUF4763 PF15960.5 OAG35620.1 - 2.1 7.6 8.2 2.6 7.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4763) Sec10 PF07393.11 OAG35621.1 - 2.7e-128 429.4 0.2 3.6e-128 429.0 0.2 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 F-box PF00646.33 OAG35621.1 - 1.8e-05 24.5 0.1 3.8e-05 23.5 0.1 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 OAG35621.1 - 0.00019 21.2 0.0 0.00051 19.9 0.0 1.7 1 0 0 1 1 1 1 F-box-like Velvet PF11754.8 OAG35622.1 - 1.1e-73 248.3 0.0 1.7e-73 247.7 0.0 1.2 1 0 0 1 1 1 1 Velvet factor adh_short_C2 PF13561.6 OAG35623.1 - 7.9e-58 195.8 3.8 9.8e-58 195.5 3.8 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG35623.1 - 2.8e-45 154.2 3.4 3.4e-45 153.9 3.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Fusion_F0 PF13044.6 OAG35623.1 - 0.089 11.4 1.3 0.21 10.2 0.3 1.8 1 1 0 2 2 2 0 Fusion glycoprotein F0, Isavirus 3HCDH_N PF02737.18 OAG35623.1 - 0.17 11.7 1.4 0.17 11.7 0.4 1.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DSBA PF01323.20 OAG35626.1 - 3.5e-17 62.8 0.2 4.3e-17 62.5 0.2 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 OAG35626.1 - 0.00028 21.1 0.1 0.00054 20.2 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 OAG35626.1 - 0.05 14.1 0.2 2.6 8.5 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin-like domain Asp PF00026.23 OAG35627.1 - 1.8e-05 24.3 0.0 0.19 11.1 0.0 3.8 3 1 0 3 3 3 3 Eukaryotic aspartyl protease Sulfate_transp PF00916.20 OAG35628.1 - 1.5e-80 270.8 9.8 1.5e-80 270.8 9.8 1.4 1 1 0 1 1 1 1 Sulfate permease family STAS PF01740.21 OAG35628.1 - 1.2e-17 63.7 0.0 2e-17 62.9 0.0 1.4 1 0 0 1 1 1 1 STAS domain DUF1286 PF06939.11 OAG35628.1 - 0.0085 16.3 4.4 2.7 8.3 1.1 3.1 2 1 0 2 2 2 2 Protein of unknown function (DUF1286) STAS_2 PF13466.6 OAG35628.1 - 0.026 14.8 0.0 0.13 12.7 0.0 2.2 2 1 0 2 2 2 0 STAS domain FTA2 PF13095.6 OAG35629.1 - 8.6e-32 110.5 0.0 3.1e-31 108.7 0.0 1.7 1 1 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Fringe PF02434.16 OAG35630.1 - 1.6e-06 27.8 0.6 1.6e-05 24.5 0.4 2.4 2 1 0 2 2 2 1 Fringe-like Galactosyl_T PF01762.21 OAG35630.1 - 4.2e-05 23.4 0.1 0.018 14.8 0.0 2.6 2 1 0 2 2 2 1 Galactosyltransferase Glyco_transf_34 PF05637.12 OAG35630.1 - 0.00035 20.4 1.1 0.00066 19.5 1.1 1.4 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family PAN_4 PF14295.6 OAG35630.1 - 0.015 15.2 0.6 0.033 14.1 0.6 1.5 1 0 0 1 1 1 0 PAN domain PAN_3 PF08277.12 OAG35630.1 - 0.024 14.5 0.9 0.054 13.3 0.9 1.6 1 0 0 1 1 1 0 PAN-like domain Trypan_PARP PF05887.11 OAG35630.1 - 0.38 10.7 11.5 0.83 9.6 11.5 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) ApbA PF02558.16 OAG35632.1 - 1e-28 99.9 0.0 1.4e-28 99.4 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 OAG35632.1 - 4e-22 78.7 0.1 9.2e-22 77.6 0.0 1.7 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA C terminal ThiF PF00899.21 OAG35632.1 - 0.011 15.1 0.9 0.018 14.4 0.9 1.3 1 0 0 1 1 1 0 ThiF family Isochorismatase PF00857.20 OAG35633.1 - 2e-31 109.5 0.1 2.7e-31 109.1 0.1 1.2 1 0 0 1 1 1 1 Isochorismatase family JmjC PF02373.22 OAG35636.1 - 2.2e-15 57.0 0.0 3.9e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 JmjC domain, hydroxylase Pkinase PF00069.25 OAG35637.1 - 5.6e-08 32.5 0.1 1.1e-07 31.4 0.1 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG35637.1 - 0.00047 19.5 0.0 0.00071 18.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase HNH_2 PF13391.6 OAG35638.1 - 0.068 13.3 0.0 0.18 11.9 0.0 1.7 1 0 0 1 1 1 0 HNH endonuclease TruB_C_2 PF16198.5 OAG35638.1 - 0.1 12.7 0.4 1.3 9.2 0.0 2.6 2 1 0 2 2 2 0 tRNA pseudouridylate synthase B C-terminal domain STAT1_TAZ2bind PF12162.8 OAG35642.1 - 0.038 13.6 0.1 0.091 12.4 0.1 1.7 1 0 0 1 1 1 0 STAT1 TAZ2 binding domain SLS PF14611.6 OAG35643.1 - 0.073 12.9 0.0 0.098 12.5 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial inner-membrane-bound regulator HSDR_N_2 PF13588.6 OAG35645.1 - 0.074 13.1 0.0 0.22 11.5 0.0 1.7 2 0 0 2 2 2 0 Type I restriction enzyme R protein N terminus (HSDR_N) HNH_2 PF13391.6 OAG35646.1 - 7.8e-07 29.1 0.2 4.2e-06 26.8 0.0 2.3 2 0 0 2 2 2 1 HNH endonuclease Pkinase PF00069.25 OAG35647.1 - 1.6e-06 27.7 0.1 3.4e-06 26.6 0.1 1.6 1 1 0 1 1 1 1 Protein kinase domain TPR_14 PF13428.6 OAG35647.1 - 0.0015 19.2 0.6 0.45 11.5 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat COX5A PF02284.16 OAG35647.1 - 0.01 15.8 1.3 0.059 13.4 0.0 2.7 4 0 0 4 4 4 0 Cytochrome c oxidase subunit Va APH PF01636.23 OAG35647.1 - 0.067 13.1 0.7 0.19 11.6 0.0 1.9 2 1 0 2 2 2 0 Phosphotransferase enzyme family TT_ORF2 PF02957.15 OAG35648.1 - 0.0087 17.0 1.2 0.011 16.7 1.2 1.1 1 0 0 1 1 1 1 TT viral ORF2 Pkinase PF00069.25 OAG35649.1 - 0.017 14.5 0.1 0.073 12.4 0.0 1.8 2 0 0 2 2 2 0 Protein kinase domain Peptidase_S24 PF00717.23 OAG35650.1 - 1.2e-09 38.0 0.0 1.1e-08 34.9 0.0 2.3 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 OAG35650.1 - 0.00011 22.0 0.0 0.0082 15.9 0.0 2.6 2 1 0 2 2 2 2 Signal peptidase, peptidase S26 KRAB PF01352.27 OAG35653.1 - 0.0036 16.9 0.0 0.0075 15.9 0.0 1.6 1 0 0 1 1 1 1 KRAB box ADH_zinc_N PF00107.26 OAG35654.1 - 1e-18 67.5 0.0 1.6e-18 66.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 OAG35654.1 - 4.9e-18 65.0 0.0 7.7e-18 64.4 0.0 1.3 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 OAG35654.1 - 3.8e-07 31.2 0.0 7.6e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Aldedh PF00171.22 OAG35655.1 - 6.8e-130 433.7 0.7 8.2e-130 433.4 0.7 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family MCM PF00493.23 OAG35656.1 - 1.3e-100 335.1 0.1 2e-100 334.5 0.1 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 OAG35656.1 - 5.9e-37 126.3 0.6 1.3e-36 125.3 0.6 1.5 1 0 0 1 1 1 1 MCM OB domain MCM6_C PF18263.1 OAG35656.1 - 9.7e-28 96.6 0.0 2.9e-27 95.0 0.0 1.9 2 0 0 2 2 2 1 MCM6 C-terminal winged-helix domain MCM_lid PF17855.1 OAG35656.1 - 5.4e-24 84.4 0.2 1.4e-23 83.1 0.2 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 OAG35656.1 - 5.7e-21 75.1 0.1 1.8e-20 73.5 0.1 1.9 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 OAG35656.1 - 1.3e-05 24.7 0.0 0.00012 21.5 0.0 2.2 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI SLAIN PF15301.6 OAG35656.1 - 0.014 14.6 1.1 0.029 13.7 1.1 1.4 1 0 0 1 1 1 0 SLAIN motif-containing family Sigma54_activat PF00158.26 OAG35656.1 - 0.017 14.9 0.0 0.033 13.9 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_5 PF07728.14 OAG35656.1 - 0.02 14.9 0.0 0.054 13.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 OAG35656.1 - 0.042 13.7 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) zf-C3H1 PF10650.9 OAG35657.1 - 4.5e-06 26.3 1.1 4.5e-06 26.3 1.1 1.8 2 0 0 2 2 2 1 Putative zinc-finger domain Sec34 PF04136.15 OAG35657.1 - 0.53 10.2 2.9 1.2 9.0 2.9 1.5 1 0 0 1 1 1 0 Sec34-like family CEP63 PF17045.5 OAG35657.1 - 0.85 9.5 23.2 0.18 11.7 17.0 2.5 2 0 0 2 2 2 0 Centrosomal protein of 63 kDa PAC4 PF16093.5 OAG35657.1 - 6 7.1 6.0 6 7.1 0.7 3.4 1 1 1 2 2 2 0 Proteasome assembly chaperone 4 FlaC_arch PF05377.11 OAG35657.1 - 6.2 7.3 5.7 1.7 9.1 1.4 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Myosin_head PF00063.21 OAG35658.1 - 3.8e-264 878.0 0.0 6.1e-264 877.4 0.0 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_N PF02736.19 OAG35658.1 - 2e-10 40.3 0.2 4.5e-10 39.2 0.2 1.6 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain GAS PF13851.6 OAG35658.1 - 0.00061 19.2 19.4 0.00061 19.2 19.4 5.4 1 1 4 5 5 5 5 Growth-arrest specific micro-tubule binding Fib_alpha PF08702.10 OAG35658.1 - 0.0037 17.5 14.5 0.0037 17.5 14.5 4.4 1 1 3 4 4 4 1 Fibrinogen alpha/beta chain family Tropomyosin_1 PF12718.7 OAG35658.1 - 0.0044 17.2 19.4 0.0044 17.2 19.4 4.9 1 1 3 4 4 4 1 Tropomyosin like AAA_19 PF13245.6 OAG35658.1 - 0.056 13.8 0.3 0.3 11.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 OAG35658.1 - 0.11 12.8 0.0 0.11 12.8 0.0 4.6 3 1 0 3 3 3 0 AAA ATPase domain AAA_22 PF13401.6 OAG35658.1 - 0.13 12.5 0.0 0.13 12.5 0.0 4.1 4 1 2 6 6 6 0 AAA domain Baculo_PEP_C PF04513.12 OAG35658.1 - 1.9 8.5 24.5 6.6 6.8 3.2 4.9 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus BcrAD_BadFG PF01869.20 OAG35659.1 - 6.3e-18 65.2 0.1 1.3e-17 64.2 0.1 1.6 1 0 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family SIS_2 PF13580.6 OAG35659.1 - 7.9e-05 22.7 4.1 0.00018 21.6 0.4 3.1 3 1 0 3 3 3 1 SIS domain ROK PF00480.20 OAG35659.1 - 0.00014 21.5 0.8 0.0048 16.4 0.1 2.2 2 0 0 2 2 2 1 ROK family SIS PF01380.22 OAG35659.1 - 0.026 14.4 1.6 0.05 13.5 0.1 2.2 2 0 0 2 2 2 0 SIS domain MFS_1 PF07690.16 OAG35660.1 - 8.9e-11 41.3 40.2 3.2e-10 39.5 40.7 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 OAG35660.1 - 3.2e-08 33.5 5.3 3.2e-08 33.5 5.3 2.8 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 EXS PF03124.14 OAG35660.1 - 0.0027 17.1 3.4 0.0075 15.6 2.9 1.9 1 1 0 1 1 1 1 EXS family NiFe_hyd_3_EhaA PF17367.2 OAG35660.1 - 0.047 13.8 0.0 0.25 11.5 0.0 2.3 1 0 0 1 1 1 0 NiFe-hydrogenase-type-3 Eha complex subunit A LapA_dom PF06305.11 OAG35660.1 - 0.31 10.9 0.1 0.31 10.9 0.1 3.9 4 1 0 4 4 4 0 Lipopolysaccharide assembly protein A domain Pet191_N PF10203.9 OAG35661.1 - 5.6e-23 81.0 0.7 7.9e-23 80.5 0.7 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 DDOST_48kD PF03345.14 OAG35662.1 - 5.9e-154 512.9 0.0 6.8e-154 512.7 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta GST_N_3 PF13417.6 OAG35666.1 - 3.4e-12 46.6 0.1 6.3e-12 45.7 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAG35666.1 - 1.7e-06 28.0 0.1 2.9e-06 27.2 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 OAG35666.1 - 2.7e-06 27.6 0.0 5.6e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OAG35666.1 - 3e-06 27.3 0.0 4.7e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OAG35666.1 - 0.00064 19.9 0.0 0.001 19.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 OAG35666.1 - 0.0083 16.4 0.0 0.05 14.0 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain Aminotran_3 PF00202.21 OAG35668.1 - 1.7e-123 412.3 0.0 2e-123 412.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 OAG35668.1 - 0.11 11.6 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II Spt4 PF06093.13 OAG35669.1 - 2e-28 98.3 0.2 6.9e-25 87.0 0.0 2.1 2 0 0 2 2 2 2 Spt4/RpoE2 zinc finger PPP5 PF08321.12 OAG35670.1 - 1.2e-33 115.2 0.4 3.2e-33 113.9 0.4 1.7 1 0 0 1 1 1 1 PPP5 TPR repeat region Metallophos PF00149.28 OAG35670.1 - 3.2e-31 109.4 0.1 4.7e-31 108.9 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_1 PF00515.28 OAG35670.1 - 1.5e-09 37.2 5.9 0.0024 17.6 1.2 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 OAG35670.1 - 2.9e-08 33.2 5.0 0.021 14.9 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 OAG35670.1 - 1.6e-07 30.9 5.3 0.013 15.2 0.4 3.5 2 1 1 3 3 3 2 TPR repeat TPR_16 PF13432.6 OAG35670.1 - 0.00015 22.4 0.4 0.33 11.6 0.5 2.7 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 OAG35670.1 - 0.00048 20.3 2.6 2.4 8.7 0.5 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 OAG35670.1 - 0.0016 18.9 1.3 0.44 11.1 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 OAG35670.1 - 0.0025 18.5 1.3 8.8 7.5 0.1 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 OAG35670.1 - 0.014 15.6 0.1 0.73 10.0 0.0 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 OAG35670.1 - 0.022 15.4 0.2 37 5.2 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 OAG35670.1 - 0.067 13.4 3.3 0.32 11.3 0.7 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat MIT PF04212.18 OAG35670.1 - 2.2 8.4 5.5 18 5.5 0.1 3.0 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain DZR PF12773.7 OAG35671.1 - 9.1 6.4 7.6 9.9 6.3 0.1 3.6 3 2 1 4 4 4 0 Double zinc ribbon DUF3669 PF12417.8 OAG35673.1 - 2.8e-17 62.7 1.2 7.4e-17 61.3 0.1 2.1 2 0 0 2 2 2 1 Zinc finger protein AMP-binding PF00501.28 OAG35674.1 - 1.2e-77 261.3 0.0 1.6e-77 260.9 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG35674.1 - 5.1e-11 43.4 0.9 1.6e-10 41.8 0.2 2.2 2 1 0 2 2 2 1 AMP-binding enzyme C-terminal domain bMG3 PF11974.8 OAG35674.1 - 0.12 12.4 0.0 0.31 11.1 0.0 1.7 1 0 0 1 1 1 0 Bacterial alpha-2-macroglobulin MG3 domain Pep3_Vps18 PF05131.14 OAG35676.1 - 9.7e-45 152.0 0.0 5.5e-44 149.6 0.0 2.3 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 OAG35676.1 - 2.8e-09 37.0 8.0 5.1e-06 26.4 0.2 3.6 3 1 0 3 3 3 2 Region in Clathrin and VPS Vps39_2 PF10367.9 OAG35676.1 - 0.00017 22.0 0.1 0.00036 21.0 0.1 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 zf-C3HC4_2 PF13923.6 OAG35676.1 - 0.00029 20.6 0.5 0.00083 19.2 0.5 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 OAG35676.1 - 0.00043 19.9 0.3 0.001 18.6 0.3 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_2 PF13639.6 OAG35676.1 - 0.00071 19.9 0.9 0.0021 18.3 0.9 1.9 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 OAG35676.1 - 0.0015 18.5 0.5 0.0037 17.2 0.5 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 OAG35676.1 - 0.0022 17.7 4.6 0.0022 17.7 4.6 2.4 2 0 0 2 2 2 1 RING-like zinc finger DUF2175 PF09943.9 OAG35676.1 - 0.0087 16.3 0.0 0.03 14.6 0.0 1.9 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2175) RPN1_RPN2_N PF17781.1 OAG35676.1 - 0.012 15.0 0.2 0.027 13.9 0.2 1.5 1 0 0 1 1 1 0 RPN1/RPN2 N-terminal domain zf-RING_UBOX PF13445.6 OAG35676.1 - 0.014 15.4 1.0 0.034 14.2 1.0 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-rbx1 PF12678.7 OAG35676.1 - 0.027 14.8 0.1 0.23 11.8 0.3 2.3 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 OAG35676.1 - 0.03 14.2 0.3 0.074 12.9 0.3 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF4337 PF14235.6 OAG35676.1 - 0.1 12.7 1.3 6.6 6.8 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) PspA_IM30 PF04012.12 OAG35676.1 - 0.52 9.9 4.6 0.35 10.4 0.1 2.6 3 0 0 3 3 3 0 PspA/IM30 family TPR_16 PF13432.6 OAG35676.1 - 1.4 9.7 4.9 28 5.4 0.2 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat MFS_1 PF07690.16 OAG35677.1 - 1.1e-29 103.6 35.2 1.1e-29 103.6 35.2 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Kdo PF06293.14 OAG35678.1 - 2.4e-06 27.0 0.0 4.3e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OAG35678.1 - 3.5e-06 27.1 0.1 0.011 15.6 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 OAG35678.1 - 0.0057 15.8 0.0 0.0088 15.1 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Pkinase_fungal PF17667.1 OAG35678.1 - 0.012 14.5 0.0 0.016 14.0 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase WaaY PF06176.11 OAG35678.1 - 0.019 14.6 0.0 0.035 13.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) baeRF_family2 PF18844.1 OAG35678.1 - 0.056 13.5 0.2 0.098 12.7 0.2 1.3 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 2 Sugar_tr PF00083.24 OAG35679.1 - 4.7e-78 263.0 25.2 5.5e-78 262.8 25.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG35679.1 - 1.5e-27 96.4 37.0 6.3e-27 94.4 32.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Spo12 PF05032.12 OAG35680.1 - 3.3e-12 46.1 0.1 9.2e-12 44.7 0.1 1.8 1 0 0 1 1 1 1 Spo12 family Neur_chan_memb PF02932.16 OAG35680.1 - 1.9 8.5 5.7 0.42 10.6 1.4 1.8 1 1 1 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region PQ-loop PF04193.14 OAG35681.1 - 1.1e-39 134.0 9.4 3.5e-21 74.7 1.5 2.6 2 0 0 2 2 2 2 PQ loop repeat HTH_Bact PF18768.1 OAG35681.1 - 0.4 10.3 1.1 0.78 9.4 0.2 1.9 2 0 0 2 2 2 0 Helix-turn-helix bacterial domain DUF2157 PF09925.9 OAG35681.1 - 0.64 9.8 4.8 13 5.6 1.6 2.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2157) DUF3585 PF12130.8 OAG35682.1 - 0.002 18.3 0.1 0.0039 17.3 0.1 1.4 1 0 0 1 1 1 1 Bivalent Mical/EHBP Rab binding domain Zn_clus PF00172.18 OAG35683.1 - 3.8e-06 26.9 8.5 3.8e-06 26.9 8.5 2.4 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FOXP-CC PF16159.5 OAG35683.1 - 0.037 14.7 0.8 0.14 12.8 0.8 1.9 1 0 0 1 1 1 0 FOXP coiled-coil domain Vir_act_alpha_C PF10400.9 OAG35683.1 - 0.12 13.1 0.0 0.34 11.6 0.0 1.8 1 0 0 1 1 1 0 Virulence activator alpha C-term PUF PF00806.19 OAG35684.1 - 3.9e-57 186.9 21.0 2.1e-09 36.6 0.2 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat DUF234 PF03008.14 OAG35684.1 - 0.14 12.6 0.2 0.35 11.3 0.2 1.6 1 0 0 1 1 1 0 Archaea bacterial proteins of unknown function sCache_2 PF17200.4 OAG35684.1 - 1.1 9.1 3.5 92 2.8 0.0 4.1 5 0 0 5 5 5 0 Single Cache domain 2 TMEM52 PF14979.6 OAG35685.1 - 0.014 15.3 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 Transmembrane 52 Mcp5_PH PF12814.7 OAG35686.1 - 5.3e-45 152.5 0.1 1.1e-44 151.5 0.1 1.6 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology PH PF00169.29 OAG35686.1 - 2.4e-05 24.8 0.0 8.2e-05 23.1 0.0 1.9 2 0 0 2 2 2 1 PH domain SHE3 PF17078.5 OAG35686.1 - 0.0082 15.9 11.1 0.053 13.2 11.1 2.3 1 1 0 1 1 1 1 SWI5-dependent HO expression protein 3 Tup_N PF08581.10 OAG35686.1 - 0.021 15.1 10.6 0.029 14.7 0.1 3.9 3 0 0 3 3 3 0 Tup N-terminal MbeD_MobD PF04899.12 OAG35686.1 - 0.57 10.3 8.3 0.036 14.2 1.0 2.9 3 0 0 3 3 3 0 MbeD/MobD like CLTH PF10607.9 OAG35687.1 - 1.2e-29 103.1 0.0 2.5e-29 102.1 0.0 1.5 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 OAG35687.1 - 4.1e-06 26.5 0.0 8.8e-06 25.5 0.0 1.6 1 0 0 1 1 1 1 LisH RRP36 PF06102.12 OAG35687.1 - 0.07 13.1 1.4 0.14 12.1 1.4 1.5 1 0 0 1 1 1 0 rRNA biogenesis protein RRP36 BST2 PF16716.5 OAG35687.1 - 3.8 8.1 5.8 1.4 9.5 1.6 2.2 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 ThrE PF06738.12 OAG35688.1 - 7.8 5.8 10.0 0.9 8.9 5.6 1.7 2 0 0 2 2 2 0 Putative threonine/serine exporter PhyH PF05721.13 OAG35689.1 - 1.3e-05 25.6 0.2 3.3e-05 24.2 0.2 1.7 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Sugar_tr PF00083.24 OAG35692.1 - 2.3e-50 171.8 9.5 4.8e-50 170.7 9.5 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG35692.1 - 2.4e-21 76.1 17.9 4.1e-21 75.3 17.7 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily CMAS PF02353.20 OAG35693.1 - 5.9e-60 202.9 0.0 7.4e-60 202.5 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 OAG35693.1 - 5.3e-09 36.1 0.0 9.5e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG35693.1 - 7.1e-06 26.6 0.0 1.5e-05 25.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG35693.1 - 1.4e-05 25.7 0.0 3e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG35693.1 - 0.0055 17.4 0.0 0.017 15.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 OAG35693.1 - 0.054 13.0 0.0 0.097 12.2 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 EXS PF03124.14 OAG35694.1 - 5.8e-116 387.4 11.6 6.6e-116 387.2 11.6 1.0 1 0 0 1 1 1 1 EXS family Sugar_tr PF00083.24 OAG35695.1 - 4.8e-34 118.0 26.8 2.3e-26 92.7 10.7 2.7 1 1 2 3 3 3 2 Sugar (and other) transporter MFS_1 PF07690.16 OAG35695.1 - 4.1e-18 65.4 29.6 2.9e-12 46.2 19.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 OAG35695.1 - 2.1e-05 23.3 6.5 0.051 12.1 6.1 2.5 2 0 0 2 2 2 2 MFS/sugar transport protein PhyH PF05721.13 OAG35696.1 - 6.7e-11 42.8 0.0 1.1e-10 42.1 0.0 1.3 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) EMC1_C PF07774.13 OAG35697.1 - 9.2e-69 231.4 0.0 1.8e-68 230.4 0.0 1.5 1 0 0 1 1 1 1 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 OAG35697.1 - 2.7e-17 63.2 11.7 5.6e-11 42.5 3.3 3.9 2 2 1 3 3 3 2 PQQ-like domain PQQ PF01011.21 OAG35697.1 - 0.00026 20.8 2.0 1 9.4 0.0 5.5 6 0 0 6 6 6 1 PQQ enzyme repeat Germane PF10646.9 OAG35697.1 - 0.0084 16.9 0.1 0.047 14.5 0.1 2.3 2 0 0 2 2 2 1 Sporulation and spore germination PQQ_3 PF13570.6 OAG35697.1 - 0.12 12.9 14.3 12 6.6 0.0 6.5 6 0 0 6 6 6 0 PQQ-like domain Fungal_trans_2 PF11951.8 OAG35698.1 - 2.8e-06 26.4 1.5 4.7e-06 25.7 1.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DnaJ_C PF01556.18 OAG35699.1 - 1.1e-37 129.3 0.9 1.5e-37 129.0 0.9 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 OAG35699.1 - 3.5e-28 97.5 3.4 5.9e-28 96.8 3.4 1.4 1 0 0 1 1 1 1 DnaJ domain KHA PF11834.8 OAG35699.1 - 0.14 12.3 0.1 2.5 8.2 0.0 2.3 2 0 0 2 2 2 0 KHA, dimerisation domain of potassium ion channel YjeF_N PF03853.15 OAG35700.1 - 5.6e-34 117.5 0.0 7e-34 117.2 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus Ribosomal_S16 PF00886.19 OAG35701.1 - 2.7e-23 81.8 0.0 6.8e-23 80.5 0.0 1.7 1 1 0 1 1 1 1 Ribosomal protein S16 CRAL_TRIO PF00650.20 OAG35702.1 - 5e-18 65.3 0.0 6.5e-18 65.0 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 OAG35702.1 - 1.7e-07 31.3 0.2 3.7e-07 30.2 0.2 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain PUL PF08324.11 OAG35703.1 - 4.8e-46 157.2 0.8 6.6e-46 156.8 0.8 1.2 1 0 0 1 1 1 1 PUL domain PFU PF09070.11 OAG35703.1 - 3.5e-43 146.5 0.4 6e-43 145.7 0.4 1.4 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.32 OAG35703.1 - 3e-29 100.6 8.8 1.8e-06 28.6 0.0 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat BBS2_Mid PF14783.6 OAG35703.1 - 0.016 15.2 0.0 5.9 7.0 0.0 3.1 2 1 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Exo_endo_phos PF03372.23 OAG35704.1 - 0.00079 19.0 1.4 0.0023 17.5 1.4 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family ERG2_Sigma1R PF04622.12 OAG35705.1 - 9.7e-89 296.2 0.0 1.2e-88 295.9 0.0 1.1 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein Hydrolase_4 PF12146.8 OAG35706.1 - 5.3e-11 42.3 0.1 2.1e-10 40.3 0.1 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OAG35706.1 - 1.1e-09 39.3 0.5 1.5e-09 38.8 0.5 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAG35706.1 - 2.5e-05 24.1 0.2 7.6e-05 22.5 0.1 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Lipase_3 PF01764.25 OAG35706.1 - 0.022 14.6 0.0 0.046 13.6 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) 3Beta_HSD PF01073.19 OAG35707.1 - 1.3e-27 96.5 0.0 4.1e-27 94.9 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 OAG35707.1 - 8.6e-14 51.6 0.0 2e-13 50.4 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 OAG35707.1 - 3.8e-10 39.4 0.0 1.1e-08 34.5 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein GDP_Man_Dehyd PF16363.5 OAG35707.1 - 3.4e-07 30.0 0.0 2.4e-06 27.2 0.0 2.3 3 0 0 3 3 3 1 GDP-mannose 4,6 dehydratase KR PF08659.10 OAG35707.1 - 2.5e-06 27.5 0.0 5.5e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OAG35707.1 - 1.4e-05 24.4 0.0 6.6e-05 22.2 0.0 2.0 3 0 0 3 3 3 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 OAG35707.1 - 0.00019 21.3 0.0 0.00048 20.1 0.0 1.8 1 1 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 OAG35707.1 - 0.00024 20.3 0.0 0.0033 16.6 0.0 2.2 2 0 0 2 2 2 1 RmlD substrate binding domain CoA_transf_3 PF02515.17 OAG35710.1 - 2.5e-30 105.8 7.5 4.1e-26 92.0 4.0 4.1 2 2 0 2 2 2 2 CoA-transferase family III DUF3246 PF11596.8 OAG35710.1 - 0.11 11.9 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) DUF2235 PF09994.9 OAG35711.1 - 4.1e-95 318.4 0.6 6.2e-95 317.8 0.6 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) An_peroxidase PF03098.15 OAG35712.1 - 2.8e-36 125.2 0.0 8.5e-20 70.8 0.0 3.3 1 1 2 3 3 3 3 Animal haem peroxidase p450 PF00067.22 OAG35712.1 - 1.4e-05 24.0 0.0 3.3e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Cytochrome P450 DPM3 PF08285.11 OAG35713.1 - 0.0023 18.1 3.3 0.096 12.9 0.0 3.2 2 1 0 2 2 2 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF4203 PF13886.6 OAG35714.1 - 1.8e-50 171.4 28.4 2.3e-50 171.1 28.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) CDV3 PF15359.6 OAG35715.1 - 0.0088 16.5 0.3 0.013 16.0 0.3 1.2 1 0 0 1 1 1 1 Carnitine deficiency-associated protein 3 Pept_tRNA_hydro PF01195.19 OAG35716.1 - 1.6e-28 99.8 0.0 2.3e-28 99.3 0.0 1.2 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase Polysacc_deac_1 PF01522.21 OAG35717.1 - 2.4e-22 79.1 0.0 4.1e-22 78.4 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 OAG35717.1 - 1.8e-10 40.8 0.6 4.1e-10 39.7 0.4 1.6 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2334) Glyco_hydro_57 PF03065.15 OAG35717.1 - 0.00025 20.4 0.6 0.00043 19.6 0.1 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 57 MTS PF05175.14 OAG35718.1 - 0.00029 20.4 0.9 0.21 11.1 0.2 3.5 3 1 0 3 3 3 1 Methyltransferase small domain Methyltransf_31 PF13847.6 OAG35718.1 - 0.00065 19.5 0.0 0.0013 18.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmC_N PF17827.1 OAG35718.1 - 0.0065 17.0 0.0 0.1 13.2 0.0 2.4 2 0 0 2 2 2 1 PrmC N-terminal domain MotA_activ PF09114.10 OAG35718.1 - 0.013 15.6 0.0 0.036 14.2 0.0 1.7 1 0 0 1 1 1 0 Transcription factor MotA, activation domain N6_Mtase PF02384.16 OAG35718.1 - 0.017 14.4 0.1 0.35 10.1 0.0 2.5 2 1 0 2 2 2 0 N-6 DNA Methylase Methyltransf_23 PF13489.6 OAG35719.1 - 9.5e-18 64.6 0.0 1.5e-17 63.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG35719.1 - 7.3e-12 45.8 0.0 1.9e-11 44.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG35719.1 - 2.2e-10 41.0 0.0 4.4e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG35719.1 - 2.5e-06 28.1 0.0 3.1e-05 24.6 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG35719.1 - 3.1e-06 27.1 0.0 0.021 14.6 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain MTS PF05175.14 OAG35719.1 - 0.00059 19.4 0.0 0.0012 18.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_16 PF10294.9 OAG35719.1 - 0.0089 15.8 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Ubie_methyltran PF01209.18 OAG35719.1 - 0.012 15.0 0.0 0.39 10.0 0.0 2.6 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 OAG35719.1 - 0.026 13.8 0.0 0.059 12.7 0.0 1.6 1 0 0 1 1 1 0 O-methyltransferase domain FtsJ PF01728.19 OAG35719.1 - 0.047 13.8 0.0 0.13 12.3 0.0 1.7 2 0 0 2 2 2 0 FtsJ-like methyltransferase Abhydrolase_3 PF07859.13 OAG35720.1 - 1e-37 130.0 0.0 1.3e-37 129.7 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 OAG35720.1 - 3.5e-06 26.2 0.0 0.014 14.3 0.0 2.1 2 0 0 2 2 2 2 Carboxylesterase family Eno-Rase_NADH_b PF12242.8 OAG35720.1 - 0.15 11.8 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Pex2_Pex12 PF04757.14 OAG35721.1 - 8.7e-45 153.0 3.3 1.2e-44 152.6 3.3 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.6 OAG35721.1 - 8.5e-11 41.6 7.0 1.4e-10 40.9 7.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAG35721.1 - 1.1e-10 41.7 10.0 1.8e-10 40.9 10.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 OAG35721.1 - 3e-10 39.8 9.6 5.3e-10 39.0 9.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAG35721.1 - 5.4e-10 39.0 7.5 1.1e-09 38.0 7.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAG35721.1 - 7.1e-09 35.5 7.2 1.2e-08 34.8 7.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 OAG35721.1 - 2.1e-08 34.1 7.9 4.4e-08 33.0 7.9 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 OAG35721.1 - 8.2e-08 32.0 6.7 1.3e-07 31.3 6.7 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 OAG35721.1 - 2.1e-06 27.8 8.6 3.8e-06 27.0 8.6 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 OAG35721.1 - 2.5e-06 27.7 8.4 5.2e-06 26.6 8.4 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 OAG35721.1 - 0.0033 17.5 3.4 0.006 16.6 3.4 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.6 OAG35721.1 - 0.0089 15.9 3.0 0.018 14.9 3.0 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-Nse PF11789.8 OAG35721.1 - 0.011 15.5 4.4 0.02 14.7 4.4 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.6 OAG35721.1 - 0.019 14.7 7.1 0.043 13.6 7.0 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_10 PF16685.5 OAG35721.1 - 0.072 13.2 6.5 0.14 12.3 6.5 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 FYVE PF01363.21 OAG35721.1 - 0.88 9.8 6.7 2.3 8.4 6.7 1.7 1 1 0 1 1 1 0 FYVE zinc finger IBR PF01485.21 OAG35721.1 - 5.1 7.4 9.0 14 6.0 8.9 1.8 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain Ytp1 PF10355.9 OAG35722.1 - 8.7e-72 241.6 14.9 2.7e-71 240.0 14.9 1.8 1 1 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 OAG35722.1 - 2.6e-30 104.3 0.4 2.6e-30 104.3 0.4 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) TctB PF07331.11 OAG35722.1 - 0.0048 17.2 0.7 0.0048 17.2 0.7 3.5 2 1 0 2 2 2 1 Tripartite tricarboxylate transporter TctB family AWPM-19 PF05512.11 OAG35722.1 - 0.01 16.1 1.1 0.024 14.8 0.1 2.2 2 0 0 2 2 2 0 AWPM-19-like family S1FA PF04689.13 OAG35722.1 - 0.84 9.8 2.3 0.71 10.1 0.3 1.9 2 0 0 2 2 2 0 DNA binding protein S1FA Polysacc_deac_1 PF01522.21 OAG35723.1 - 5.2e-32 110.4 0.0 1.2e-31 109.2 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide deacetylase DUF2334 PF10096.9 OAG35723.1 - 0.025 14.2 0.0 0.038 13.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) ZnuA PF01297.17 OAG35723.1 - 0.039 13.4 0.0 0.05 13.0 0.0 1.2 1 0 0 1 1 1 0 Zinc-uptake complex component A periplasmic DUF3079 PF11278.8 OAG35723.1 - 3 7.7 4.8 0.89 9.4 0.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3079) Ysc84 PF04366.12 OAG35724.1 - 1.8e-42 144.1 0.3 3.1e-42 143.4 0.3 1.4 1 0 0 1 1 1 1 Las17-binding protein actin regulator Polysacc_deac_3 PF15421.6 OAG35724.1 - 0.1 11.1 0.0 0.15 10.5 0.0 1.1 1 0 0 1 1 1 0 Putative polysaccharide deacetylase ECH_1 PF00378.20 OAG35725.1 - 1.9e-22 79.8 0.0 2.2e-22 79.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAG35725.1 - 0.00023 20.8 0.0 0.00027 20.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 OAG35725.1 - 0.15 12.0 0.0 13 5.7 0.0 2.3 2 0 0 2 2 2 0 Peptidase family S49 ABC_membrane PF00664.23 OAG35726.1 - 6.1e-100 334.4 35.0 3.1e-53 181.2 18.0 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 OAG35726.1 - 1.7e-67 226.1 0.2 3e-32 112.0 0.0 2.9 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.19 OAG35726.1 - 4.5e-14 52.4 0.4 1.3e-05 24.8 0.1 4.0 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 OAG35726.1 - 2.9e-07 31.0 2.7 0.007 16.8 0.1 3.2 2 1 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 OAG35726.1 - 3.3e-06 27.1 0.1 0.027 14.4 0.0 3.0 3 0 0 3 3 3 2 RsgA GTPase ABC_ATPase PF09818.9 OAG35726.1 - 3.9e-06 25.9 2.9 0.025 13.4 0.1 3.0 3 1 0 3 3 3 2 Predicted ATPase of the ABC class AAA_29 PF13555.6 OAG35726.1 - 4.5e-06 26.3 3.8 0.0076 16.0 0.3 3.2 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_21 PF13304.6 OAG35726.1 - 4.1e-05 23.5 3.3 0.059 13.2 0.0 3.7 2 2 1 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system DUF87 PF01935.17 OAG35726.1 - 0.00013 22.2 2.9 0.026 14.6 0.6 3.1 3 1 0 3 3 2 1 Helicase HerA, central domain AAA_22 PF13401.6 OAG35726.1 - 0.00018 21.8 5.8 0.33 11.2 0.1 4.9 4 2 0 4 4 4 2 AAA domain Zeta_toxin PF06414.12 OAG35726.1 - 0.00019 20.8 0.4 0.32 10.2 0.0 3.2 3 0 0 3 3 3 2 Zeta toxin AAA_25 PF13481.6 OAG35726.1 - 0.00019 21.1 0.1 0.092 12.3 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 OAG35726.1 - 0.00023 21.0 0.1 0.66 9.6 0.1 2.8 2 1 0 2 2 2 2 AAA ATPase domain AAA_7 PF12775.7 OAG35726.1 - 0.002 17.7 0.0 2 7.9 0.0 2.6 3 0 0 3 3 2 2 P-loop containing dynein motor region SbcCD_C PF13558.6 OAG35726.1 - 0.0026 18.0 2.0 4.8 7.5 0.1 3.7 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit G-alpha PF00503.20 OAG35726.1 - 0.0036 16.5 0.0 2.4 7.3 0.0 2.5 2 0 0 2 2 2 2 G-protein alpha subunit AAA_28 PF13521.6 OAG35726.1 - 0.0036 17.6 0.3 0.51 10.6 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 OAG35726.1 - 0.0042 17.3 0.0 1.6 8.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 OAG35726.1 - 0.0055 17.1 5.0 7.8 6.9 0.3 4.2 2 2 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 OAG35726.1 - 0.006 17.1 0.2 8.1 7.0 0.0 2.9 3 0 0 3 3 2 0 AAA domain AAA_5 PF07728.14 OAG35726.1 - 0.013 15.5 0.2 13 5.8 0.0 3.4 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_23 PF13476.6 OAG35726.1 - 0.018 15.5 0.3 3.1 8.2 0.0 3.2 3 0 0 3 3 2 0 AAA domain DUF815 PF05673.13 OAG35726.1 - 0.028 13.6 0.0 6.8 5.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_30 PF13604.6 OAG35726.1 - 0.062 13.0 8.5 2 8.1 0.0 3.8 5 0 0 5 5 4 0 AAA domain RNA_helicase PF00910.22 OAG35726.1 - 0.065 13.6 0.0 15 6.0 0.0 3.6 3 0 0 3 3 3 0 RNA helicase MMR_HSR1 PF01926.23 OAG35726.1 - 0.11 12.6 1.2 20 5.3 0.0 3.5 3 0 0 3 3 3 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 OAG35726.1 - 0.14 11.5 1.9 13 5.1 0.1 3.2 3 0 0 3 3 3 0 FtsK/SpoIIIE family Rad17 PF03215.15 OAG35726.1 - 0.26 11.2 0.7 0.99 9.3 0.0 2.2 3 0 0 3 3 2 0 Rad17 P-loop domain Swi5 PF07061.11 OAG35727.1 - 5.6e-18 64.8 8.8 3.1e-17 62.4 0.4 2.8 2 1 0 2 2 2 2 Swi5 GHL13 PF14883.6 OAG35727.1 - 0.11 11.5 1.0 0.13 11.3 1.0 1.1 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase family 13 DUF4407 PF14362.6 OAG35727.1 - 0.2 11.0 2.2 0.24 10.7 2.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Lebercilin PF15619.6 OAG35727.1 - 0.29 10.8 7.8 0.11 12.2 4.8 1.7 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Macoilin PF09726.9 OAG35727.1 - 3.5 6.1 16.5 3.9 5.9 16.5 1.1 1 0 0 1 1 1 0 Macoilin family PAP1 PF08601.10 OAG35727.1 - 6.2 6.4 22.0 7.4 6.2 22.0 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 Lactamase_B_6 PF16661.5 OAG35728.1 - 6.1e-63 211.8 0.0 1e-62 211.1 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 OAG35728.1 - 1.1e-39 136.4 0.0 1.1e-39 136.4 0.0 3.1 3 0 0 3 3 3 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.8 OAG35728.1 - 3.5e-15 56.3 0.0 1.1e-14 54.7 0.0 1.9 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.12 OAG35728.1 - 8.5e-11 41.6 0.0 2.8e-10 40.0 0.0 2.0 2 0 0 2 2 2 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B PF00753.27 OAG35728.1 - 0.032 14.2 0.3 0.1 12.6 0.3 1.9 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily RIO1 PF01163.22 OAG35729.1 - 3.2e-05 23.6 0.0 5.1e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 OAG35729.1 - 0.00011 22.2 0.0 0.0038 17.2 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 OAG35729.1 - 0.00026 20.4 0.0 0.00045 19.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 OAG35729.1 - 0.035 13.5 0.0 0.057 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain WaaY PF06176.11 OAG35729.1 - 0.079 12.6 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Pkinase_fungal PF17667.1 OAG35729.1 - 0.081 11.7 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase FMN_dh PF01070.18 OAG35730.1 - 9.5e-108 360.3 0.0 2e-65 221.1 0.0 2.0 2 0 0 2 2 2 2 FMN-dependent dehydrogenase Glu_synthase PF01645.17 OAG35730.1 - 7e-05 22.1 0.0 0.0001 21.6 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 OAG35730.1 - 7.8e-05 21.8 0.1 0.00013 21.1 0.1 1.3 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.21 OAG35730.1 - 0.049 13.1 0.0 0.19 11.2 0.0 1.8 2 0 0 2 2 2 0 Histidine biosynthesis protein DHDPS PF00701.22 OAG35731.1 - 1.4e-61 207.7 0.0 1.6e-61 207.6 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family X8 PF07983.13 OAG35731.1 - 0.027 15.2 0.0 0.055 14.2 0.0 1.4 1 0 0 1 1 1 0 X8 domain Fungal_trans_2 PF11951.8 OAG35732.1 - 4e-44 151.0 0.4 6.4e-44 150.3 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pkinase PF00069.25 OAG35732.1 - 2.1e-13 50.3 0.0 3.8e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG35732.1 - 6.1e-10 38.8 0.0 1.3e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Zn_clus PF00172.18 OAG35732.1 - 3.2e-09 36.8 6.3 8.1e-09 35.5 6.3 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Kdo PF06293.14 OAG35732.1 - 0.0049 16.2 0.4 0.014 14.7 0.4 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family adh_short PF00106.25 OAG35733.1 - 1.1e-19 70.7 0.0 1.4e-19 70.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG35733.1 - 4e-19 69.1 0.0 5e-19 68.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG35733.1 - 0.00012 22.0 0.0 0.00022 21.2 0.0 1.4 1 0 0 1 1 1 1 KR domain DUF460 PF04312.13 OAG35733.1 - 0.012 15.4 0.0 0.018 14.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF460) SIS PF01380.22 OAG35733.1 - 0.092 12.6 0.0 0.2 11.5 0.0 1.5 2 0 0 2 2 2 0 SIS domain Arrestin_C PF02752.22 OAG35735.1 - 3.6e-08 34.0 0.0 1.6e-07 31.9 0.0 2.0 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 OAG35735.1 - 6.3e-05 23.1 0.0 0.00016 21.7 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 OAG35735.1 - 0.058 13.1 0.5 1.9 8.2 0.0 2.8 2 1 1 3 3 3 0 Arrestin_N terminal like Sugar_tr PF00083.24 OAG35736.1 - 1.2e-116 390.3 19.7 1.7e-116 389.8 19.7 1.2 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG35736.1 - 6.5e-29 100.9 63.3 5.3e-24 84.8 36.9 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4131 PF13567.6 OAG35736.1 - 1.6 8.4 4.9 50 3.5 0.4 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) MFS_1 PF07690.16 OAG35737.1 - 3.3e-27 95.4 19.0 3.3e-27 95.4 19.0 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG35737.1 - 9.7e-11 41.2 1.2 9.7e-11 41.2 1.2 3.2 3 0 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 OAG35737.1 - 8.9e-07 27.7 2.0 8.9e-07 27.7 2.0 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) PUCC PF03209.15 OAG35737.1 - 0.0043 16.1 0.1 0.0043 16.1 0.1 2.5 3 0 0 3 3 3 1 PUCC protein NAD_binding_1 PF00175.21 OAG35738.1 - 1e-15 58.3 0.0 2.4e-15 57.1 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Globin PF00042.22 OAG35738.1 - 2.3e-10 41.0 0.1 2.9e-09 37.4 0.0 2.6 3 0 0 3 3 3 1 Globin NAD_binding_6 PF08030.12 OAG35738.1 - 9.9e-07 29.0 0.1 6.9e-05 23.0 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Protoglobin PF11563.8 OAG35738.1 - 5.6e-06 26.3 0.1 1.2e-05 25.3 0.1 1.5 1 0 0 1 1 1 1 Protoglobin FAD_binding_6 PF00970.24 OAG35738.1 - 2.6e-05 24.5 0.0 5.3e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Semialdhyde_dh PF01118.24 OAG35738.1 - 0.099 13.1 0.0 8.8 6.8 0.0 3.0 2 1 1 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain Glyoxalase_6 PF18029.1 OAG35739.1 - 1.8e-06 28.7 0.0 3.1e-06 27.9 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.25 OAG35739.1 - 0.0011 19.2 0.0 0.13 12.5 0.0 2.3 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Ntox37 PF15535.6 OAG35739.1 - 0.1 13.0 0.5 0.76 10.2 0.1 2.5 2 2 0 2 2 2 0 Bacterial toxin 37 Vps36_ESCRT-II PF11605.8 OAG35740.1 - 0.0018 18.4 0.0 0.0041 17.3 0.0 1.6 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 UCR_hinge PF02320.16 OAG35741.1 - 2.3e-27 95.0 10.8 4.9e-27 93.9 10.8 1.6 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein DUF4211 PF13926.6 OAG35741.1 - 0.034 14.2 0.8 0.06 13.4 0.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4211) Mpp10 PF04006.12 OAG35741.1 - 0.051 12.0 19.0 0.074 11.5 19.0 1.3 1 0 0 1 1 1 0 Mpp10 protein CobT PF06213.12 OAG35741.1 - 0.056 12.8 19.2 0.065 12.6 19.2 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CDC45 PF02724.14 OAG35741.1 - 0.1 10.9 12.8 0.1 10.9 12.8 1.0 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 OAG35741.1 - 0.37 10.2 21.6 0.41 10.0 21.6 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 OAG35741.1 - 0.49 8.5 21.2 0.53 8.4 21.2 1.0 1 0 0 1 1 1 0 Nop14-like family DUF913 PF06025.12 OAG35741.1 - 1 8.3 4.2 1.1 8.2 4.2 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) LAP1C PF05609.12 OAG35741.1 - 1.5 7.8 12.5 1.7 7.7 12.5 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DNA_pol_phi PF04931.13 OAG35741.1 - 1.6 6.7 25.1 1.9 6.5 25.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi SAPS PF04499.15 OAG35741.1 - 2.8 6.6 5.8 3 6.5 5.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RRN3 PF05327.11 OAG35741.1 - 3 6.3 10.7 3.4 6.1 10.7 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 TRAP_alpha PF03896.16 OAG35741.1 - 3 7.0 9.4 3.7 6.7 9.4 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit SpoIIIAH PF12685.7 OAG35741.1 - 3 7.6 9.3 3.5 7.4 9.3 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein Raftlin PF15250.6 OAG35741.1 - 4 6.1 8.0 4.6 5.9 8.0 1.1 1 0 0 1 1 1 0 Raftlin BUD22 PF09073.10 OAG35741.1 - 5 6.4 20.4 5.8 6.1 20.4 1.1 1 0 0 1 1 1 0 BUD22 PAF PF15715.5 OAG35741.1 - 7.4 7.2 14.5 13 6.3 14.5 1.6 1 1 0 1 1 1 0 PCNA-associated factor histone like domain MFS_1 PF07690.16 OAG35742.1 - 2.7e-25 89.1 30.6 2.7e-25 89.1 30.6 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 OAG35742.1 - 1.3e-05 24.0 16.2 0.00019 20.2 2.4 2.5 3 0 0 3 3 3 2 MFS/sugar transport protein Uds1 PF15456.6 OAG35743.1 - 9.3e-42 142.3 7.2 9.3e-42 142.3 7.2 5.9 3 2 2 6 6 6 1 Up-regulated During Septation DUF4618 PF15397.6 OAG35743.1 - 0.00017 21.1 20.8 0.00017 21.1 20.8 5.5 4 1 1 6 6 6 2 Domain of unknown function (DUF4618) Golgin_A5 PF09787.9 OAG35743.1 - 0.00034 20.2 16.3 0.00034 20.2 16.3 5.7 2 2 5 7 7 7 1 Golgin subfamily A member 5 TMF_DNA_bd PF12329.8 OAG35743.1 - 0.0049 16.8 2.5 0.0049 16.8 2.5 9.7 7 3 3 10 10 10 2 TATA element modulatory factor 1 DNA binding HR1 PF02185.16 OAG35743.1 - 0.0079 16.3 1.5 0.0079 16.3 1.5 8.7 7 2 1 8 8 8 1 Hr1 repeat Hemagglutinin PF00509.18 OAG35743.1 - 0.66 8.3 7.3 0.65 8.3 0.8 3.1 2 1 1 3 3 3 0 Haemagglutinin DUF3618 PF12277.8 OAG35743.1 - 9.4 6.6 15.9 2.7 8.3 1.0 4.9 4 0 0 4 4 4 0 Protein of unknown function (DUF3618) Slu7 PF11708.8 OAG35744.1 - 1.3e-67 228.5 21.4 1.3e-67 228.5 21.4 2.9 2 1 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.6 OAG35744.1 - 0.078 12.7 0.5 0.078 12.7 0.5 1.6 2 0 0 2 2 2 0 Zinc knuckle DNA_pol_B PF00136.21 OAG35745.1 - 4.1e-102 342.2 0.0 5.6e-102 341.8 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 OAG35745.1 - 2.2e-19 69.8 0.0 5.5e-13 48.8 0.0 2.3 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain Fungal_trans PF04082.18 OAG35745.1 - 6e-07 28.8 0.0 1.7e-06 27.2 0.0 1.8 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C4pol PF14260.6 OAG35745.1 - 5.2e-06 26.8 2.4 5.2e-06 26.8 2.4 2.1 2 0 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta TMEM164 PF14808.6 OAG35745.1 - 0.15 11.4 0.0 0.3 10.4 0.0 1.4 1 0 0 1 1 1 0 TMEM164 family TAL_FSA PF00923.19 OAG35746.1 - 1.9e-28 99.7 0.1 2.4e-28 99.3 0.1 1.2 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase adh_short_C2 PF13561.6 OAG35747.1 - 1.9e-47 161.8 0.2 3.1e-45 154.6 0.0 2.3 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG35747.1 - 4.2e-35 121.0 1.0 5.1e-28 97.9 0.0 2.1 1 1 1 2 2 2 2 short chain dehydrogenase KR PF08659.10 OAG35747.1 - 5.5e-11 42.7 0.3 1.2e-10 41.6 0.3 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG35747.1 - 4.3e-09 36.2 0.1 1e-08 35.0 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAG35747.1 - 1.2e-05 24.9 0.1 0.0039 16.6 0.1 2.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 OAG35747.1 - 0.0014 18.2 0.1 0.0076 15.8 0.0 2.1 2 0 0 2 2 2 1 NmrA-like family NAD_binding_4 PF07993.12 OAG35747.1 - 0.02 14.1 0.0 0.21 10.7 0.0 2.1 2 0 0 2 2 2 0 Male sterility protein RmlD_sub_bind PF04321.17 OAG35747.1 - 0.034 13.2 0.1 0.083 12.0 0.1 1.8 1 1 0 1 1 1 0 RmlD substrate binding domain DapB_N PF01113.20 OAG35747.1 - 0.04 14.0 0.0 0.063 13.4 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Polysacc_synt_2 PF02719.15 OAG35747.1 - 0.041 13.0 0.4 0.15 11.2 0.4 1.9 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 OAG35747.1 - 0.053 13.4 0.1 0.77 9.6 0.0 2.2 2 0 0 2 2 2 0 NAD(P)H-binding DUF1815 PF08844.10 OAG35747.1 - 0.095 12.7 0.1 0.97 9.4 0.0 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF1815) APH PF01636.23 OAG35749.1 - 6.8e-11 42.5 0.3 1.8e-10 41.1 0.3 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 OAG35749.1 - 7.2e-06 25.6 0.0 0.1 11.9 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Choline_kinase PF01633.20 OAG35749.1 - 1.6e-05 24.6 0.1 3.2e-05 23.6 0.0 1.5 2 0 0 2 2 2 1 Choline/ethanolamine kinase RIO1 PF01163.22 OAG35749.1 - 0.011 15.4 0.0 0.9 9.1 0.0 2.2 2 0 0 2 2 2 0 RIO1 family Trypsin_2 PF13365.6 OAG35751.1 - 0.0019 19.1 0.0 0.0049 17.8 0.0 1.7 1 1 0 1 1 1 1 Trypsin-like peptidase domain Sugar_tr PF00083.24 OAG35752.1 - 1.4e-86 291.2 26.1 1.6e-86 290.9 26.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG35752.1 - 1.5e-14 53.7 50.1 6.9e-09 35.1 19.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ox_reductase_C PF08635.10 OAG35753.1 - 7e-62 207.3 0.1 1e-61 206.7 0.1 1.3 1 0 0 1 1 1 1 Putative oxidoreductase C terminal domain GFO_IDH_MocA PF01408.22 OAG35753.1 - 5.1e-15 56.4 0.0 8.2e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 OAG35753.1 - 0.00096 19.2 0.0 0.0023 17.9 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Proteasome PF00227.26 OAG35755.1 - 6.7e-27 94.2 0.0 9.9e-27 93.7 0.0 1.3 1 0 0 1 1 1 1 Proteasome subunit MMM1 PF10296.9 OAG35755.1 - 4.7e-05 22.6 0.0 0.00018 20.7 0.0 1.9 1 1 1 2 2 2 1 Maintenance of mitochondrial morphology protein 1 DUF3742 PF12553.8 OAG35756.1 - 0.046 13.9 0.2 0.046 13.9 0.2 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3742) R3H PF01424.22 OAG35757.1 - 1.7e-17 63.1 1.2 2.3e-17 62.7 0.0 1.9 2 0 0 2 2 2 1 R3H domain MT0933_antitox PF14013.6 OAG35758.1 - 0.91 9.9 7.5 1.5 9.2 3.4 2.8 2 1 0 2 2 2 0 MT0933-like antitoxin protein Proton_antipo_N PF00662.20 OAG35759.1 - 0.6 10.2 4.8 4.6 7.4 0.9 3.2 3 0 0 3 3 3 0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus HET PF06985.11 OAG35760.1 - 6.3e-31 107.7 0.4 1.1e-30 106.9 0.4 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DSBA PF01323.20 OAG35761.1 - 4.4e-15 56.0 0.0 5.8e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 DSBA-like thioredoxin domain cobW PF02492.19 OAG35762.1 - 7.3e-41 139.7 0.0 1.2e-40 139.0 0.0 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.14 OAG35762.1 - 0.00038 20.4 0.0 0.00098 19.0 0.0 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B RsgA_GTPase PF03193.16 OAG35762.1 - 0.0018 18.2 0.1 2.2 8.2 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 OAG35762.1 - 0.022 15.0 0.0 0.053 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 OAG35762.1 - 0.031 14.0 0.2 0.95 9.2 0.1 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain Viral_helicase1 PF01443.18 OAG35762.1 - 0.11 12.2 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.15 OAG35762.1 - 0.15 11.9 0.1 0.38 10.6 0.1 1.7 1 0 0 1 1 1 0 NTPase adh_short PF00106.25 OAG35763.1 - 1.4e-19 70.3 0.0 9.5e-19 67.6 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG35763.1 - 7.9e-11 42.0 0.0 1.5e-10 41.0 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG35763.1 - 3.1e-09 37.0 0.0 4.6e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG35763.1 - 2.3e-05 24.0 0.0 3.8e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Orn_Arg_deC_N PF02784.16 OAG35764.1 - 2e-80 269.7 0.0 2.9e-80 269.2 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 OAG35764.1 - 2.9e-21 75.5 0.0 4.9e-21 74.8 0.0 1.5 2 0 0 2 2 2 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.24 OAG35764.1 - 5e-05 22.8 0.0 9.2e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Methyltransf_16 PF10294.9 OAG35765.1 - 4.4e-46 156.8 0.0 9.2e-46 155.7 0.0 1.5 1 1 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 OAG35765.1 - 0.00077 19.3 0.0 0.0013 18.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OAG35765.1 - 0.0041 16.7 0.1 0.0068 16.0 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 OAG35765.1 - 0.0073 17.0 0.0 0.015 16.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 OAG35765.1 - 0.01 15.6 0.0 0.016 15.0 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) AA_permease PF00324.21 OAG35767.1 - 4.4e-142 474.0 34.2 5.5e-142 473.7 34.2 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAG35767.1 - 4.7e-34 117.9 34.2 5.9e-34 117.6 34.2 1.1 1 0 0 1 1 1 1 Amino acid permease DUF4781 PF16013.5 OAG35767.1 - 0.006 15.4 0.3 0.011 14.6 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4781) Dsl1_C PF11989.8 OAG35768.1 - 6.1e-06 26.1 0.1 4e-05 23.4 0.0 2.4 2 0 0 2 2 2 1 Retrograde transport protein Dsl1 C terminal NAGidase PF07555.13 OAG35768.1 - 0.043 13.1 0.1 0.24 10.7 0.1 2.0 2 0 0 2 2 2 0 beta-N-acetylglucosaminidase BLI1 PF17324.2 OAG35768.1 - 0.61 10.8 3.7 13 6.5 0.1 2.9 2 0 0 2 2 2 0 BLOC-1 interactor 1 Seryl_tRNA_N PF02403.22 OAG35768.1 - 8.3 6.7 7.6 2.5 8.4 0.6 3.4 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain MFS_1 PF07690.16 OAG35771.1 - 5.7e-24 84.7 42.8 2.4e-23 82.6 43.4 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Neur_chan_memb PF02932.16 OAG35771.1 - 0.083 12.9 0.9 0.12 12.4 0.9 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region HMGL-like PF00682.19 OAG35772.1 - 8e-43 146.9 0.0 2.5e-32 112.5 0.1 2.0 2 0 0 2 2 2 2 HMGL-like LCM PF04072.14 OAG35775.1 - 8.5e-16 58.4 0.0 3.8e-15 56.3 0.0 1.9 2 0 0 2 2 2 1 Leucine carboxyl methyltransferase Cupin_8 PF13621.6 OAG35775.1 - 7.4e-12 45.5 0.0 1.3e-11 44.7 0.0 1.3 1 0 0 1 1 1 1 Cupin-like domain Kelch_4 PF13418.6 OAG35775.1 - 3.3e-09 36.6 1.6 8.7e-05 22.5 0.0 4.3 4 0 0 4 4 4 2 Galactose oxidase, central domain sCache_3_2 PF17203.4 OAG35775.1 - 0.23 11.6 0.0 0.44 10.7 0.0 1.3 1 0 0 1 1 1 0 Single cache domain 3 L51_S25_CI-B8 PF05047.16 OAG35778.1 - 2.2e-06 27.5 0.1 4.7e-06 26.4 0.1 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain DUF108 PF01958.18 OAG35778.1 - 0.064 13.6 0.1 0.13 12.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF108 Glyco_tranf_2_3 PF13641.6 OAG35779.1 - 2.4e-21 76.7 0.0 3.6e-21 76.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 OAG35779.1 - 3.1e-16 59.9 1.9 3.1e-16 59.9 1.9 2.1 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 OAG35779.1 - 7.5e-16 58.4 0.0 1.2e-15 57.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Cellulose_synt PF03552.14 OAG35779.1 - 1.4e-09 37.1 1.9 2.9e-08 32.7 0.1 2.8 2 1 1 3 3 3 1 Cellulose synthase Glyco_transf_21 PF13506.6 OAG35779.1 - 3.5e-09 36.4 0.0 1e-08 34.8 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 21 Neugrin PF06413.11 OAG35780.1 - 1.2e-14 54.9 1.4 2.2e-14 54.0 0.9 1.6 1 1 0 1 1 1 1 Neugrin MRP-L20 PF12824.7 OAG35780.1 - 4.9e-09 36.6 4.4 1.2e-08 35.2 4.4 1.6 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 DUF2236 PF09995.9 OAG35781.1 - 1.5e-33 116.9 0.1 2.1e-33 116.4 0.1 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) GCP_C_terminal PF04130.13 OAG35782.1 - 6.6e-68 229.4 0.5 6.6e-68 229.4 0.5 2.1 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 OAG35782.1 - 6.6e-07 29.2 10.2 1.3e-05 25.0 10.2 2.6 1 1 0 1 1 1 1 Gamma tubulin complex component N-terminal MFS_1 PF07690.16 OAG35783.1 - 8.2e-43 146.7 30.8 8.2e-43 146.7 30.8 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG35783.1 - 3.2e-07 29.6 7.3 3.2e-07 29.6 7.3 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter VIT1 PF01988.19 OAG35783.1 - 0.15 11.9 8.5 0.092 12.6 2.5 2.4 2 0 0 2 2 2 0 VIT family Clr5 PF14420.6 OAG35784.1 - 2.1e-05 24.6 0.0 4.2e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Clr5 domain Eaf7 PF07904.13 OAG35785.1 - 1.3e-21 76.9 0.9 3.6e-21 75.5 0.0 2.0 2 0 0 2 2 2 1 Chromatin modification-related protein EAF7 NOA36 PF06524.12 OAG35785.1 - 0.92 8.8 6.0 1.3 8.3 6.0 1.2 1 0 0 1 1 1 0 NOA36 protein PPP4R2 PF09184.11 OAG35785.1 - 3.3 7.2 9.3 5.1 6.6 9.3 1.3 1 0 0 1 1 1 0 PPP4R2 Nop14 PF04147.12 OAG35785.1 - 4.7 5.3 9.1 5.8 5.0 9.1 1.1 1 0 0 1 1 1 0 Nop14-like family Sec5 PF15469.6 OAG35786.1 - 1.9e-36 125.6 0.0 1.1e-35 123.2 0.0 2.3 2 0 0 2 2 2 1 Exocyst complex component Sec5 Vps51 PF08700.11 OAG35786.1 - 1.3e-05 25.2 0.1 4.8e-05 23.4 0.1 2.1 1 0 0 1 1 1 1 Vps51/Vps67 DUF685 PF05085.12 OAG35786.1 - 0.065 12.5 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF685) Iso_dh PF00180.20 OAG35787.1 - 2.2e-99 332.9 0.0 2.4e-99 332.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Helicase_C PF00271.31 OAG35788.1 - 3.7e-13 49.8 0.1 9.7e-13 48.4 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG35788.1 - 2.2e-05 24.5 0.0 6.5e-05 23.0 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 OAG35788.1 - 0.13 12.1 0.0 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 DEAD/DEAH box helicase ADH_N PF08240.12 OAG35789.1 - 1.5e-18 66.6 0.2 3.8e-18 65.3 0.2 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG35789.1 - 1.2e-11 44.7 0.1 1.7e-11 44.2 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 OAG35789.1 - 6.1e-06 25.9 0.1 1e-05 25.1 0.1 1.4 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus Shikimate_DH PF01488.20 OAG35789.1 - 0.002 18.2 0.1 0.0044 17.1 0.1 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox_2 PF07992.14 OAG35789.1 - 0.008 15.4 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAG35789.1 - 0.012 15.2 0.8 0.022 14.4 0.8 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.19 OAG35789.1 - 0.029 13.8 0.2 0.056 12.8 0.0 1.5 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 OAG35789.1 - 0.043 13.4 0.1 0.082 12.5 0.1 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Sacchrp_dh_NADP PF03435.18 OAG35789.1 - 0.077 13.3 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain FAD_binding_3 PF01494.19 OAG35789.1 - 0.14 11.3 0.2 0.23 10.7 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 OAG35789.1 - 0.44 11.1 2.0 0.58 10.8 0.3 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase adh_short_C2 PF13561.6 OAG35790.1 - 9.1e-57 192.3 0.8 1.1e-56 192.1 0.8 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG35790.1 - 7.1e-46 156.1 0.8 8.7e-46 155.8 0.8 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG35790.1 - 3.4e-14 53.2 1.1 4.6e-14 52.7 1.1 1.2 1 0 0 1 1 1 1 KR domain TRI12 PF06609.13 OAG35791.1 - 1.7e-42 145.7 22.3 3.2e-26 91.9 15.4 2.0 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG35791.1 - 3.2e-19 69.1 46.0 3.2e-19 69.1 46.0 2.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Fungal_trans PF04082.18 OAG35792.1 - 2.4e-16 59.6 1.3 6.6e-16 58.1 0.6 2.1 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG35792.1 - 6.3e-07 29.4 12.3 1.3e-06 28.4 12.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_N PF08240.12 OAG35793.1 - 1.2e-25 89.5 0.6 1.2e-25 89.5 0.6 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG35793.1 - 3.4e-22 78.8 0.1 5.5e-22 78.1 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAG35793.1 - 2.9e-15 57.5 0.0 5.3e-15 56.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TrkA_N PF02254.18 OAG35793.1 - 0.00011 22.4 0.1 0.00029 21.1 0.0 1.7 2 0 0 2 2 2 1 TrkA-N domain Glu_dehyd_C PF16912.5 OAG35793.1 - 0.00089 18.8 0.0 0.0012 18.3 0.0 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 OAG35793.1 - 0.012 14.9 0.1 0.021 14.1 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ThiF PF00899.21 OAG35793.1 - 0.014 14.7 0.2 0.025 13.9 0.2 1.3 1 0 0 1 1 1 0 ThiF family Mur_ligase PF01225.25 OAG35793.1 - 0.043 14.1 0.2 0.1 13.0 0.2 1.6 1 0 0 1 1 1 0 Mur ligase family, catalytic domain Methyltransf_31 PF13847.6 OAG35793.1 - 0.07 12.9 0.1 0.16 11.8 0.1 1.6 1 1 0 1 1 1 0 Methyltransferase domain IGFBP PF00219.18 OAG35793.1 - 0.086 13.5 0.6 0.21 12.3 0.6 1.6 1 0 0 1 1 1 0 Insulin-like growth factor binding protein DHHC PF01529.20 OAG35793.1 - 5 7.2 5.8 9.4 6.3 5.8 1.4 1 0 0 1 1 1 0 DHHC palmitoyltransferase adh_short PF00106.25 OAG35794.1 - 2.7e-48 164.0 0.3 3.6e-48 163.6 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG35794.1 - 2.2e-47 161.6 0.5 2.6e-47 161.4 0.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG35794.1 - 2.7e-11 43.7 0.6 3.9e-11 43.2 0.6 1.2 1 0 0 1 1 1 1 KR domain SnoaL_4 PF13577.6 OAG35795.1 - 4.1e-23 81.9 0.5 4.9e-23 81.7 0.5 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_3 PF13474.6 OAG35795.1 - 0.0011 19.2 0.9 0.0018 18.5 0.9 1.3 1 1 0 1 1 1 1 SnoaL-like domain NTF2 PF02136.20 OAG35795.1 - 0.015 15.9 0.0 0.022 15.3 0.0 1.3 1 0 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain DUF4440 PF14534.6 OAG35795.1 - 0.039 14.4 0.2 0.053 13.9 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) adh_short_C2 PF13561.6 OAG35796.1 - 1.3e-35 123.0 0.0 9.7e-28 97.3 0.1 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG35796.1 - 2.4e-32 112.0 0.2 3e-32 111.7 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG35796.1 - 2.2e-07 30.9 0.1 5.8e-07 29.6 0.1 1.6 1 1 0 1 1 1 1 KR domain Methyltransf_25 PF13649.6 OAG35796.1 - 0.084 13.6 0.0 0.22 12.3 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain p450 PF00067.22 OAG35797.1 - 4.5e-66 223.5 0.0 5.1e-66 223.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DTW PF03942.15 OAG35797.1 - 0.13 11.9 0.1 0.29 10.8 0.1 1.5 1 0 0 1 1 1 0 DTW domain adh_short PF00106.25 OAG35798.1 - 1.6e-35 122.3 5.7 3.1e-35 121.4 5.8 1.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG35798.1 - 4.6e-29 101.6 2.1 7e-29 101.0 2.1 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG35798.1 - 7.2e-06 26.0 2.6 1.1e-05 25.5 2.6 1.2 1 0 0 1 1 1 1 KR domain Sugar_tr PF00083.24 OAG35799.1 - 9.5e-70 235.7 24.4 1.1e-69 235.4 24.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG35799.1 - 1.9e-23 83.0 22.3 1.9e-23 83.0 22.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3593 PF12159.8 OAG35799.1 - 1.2 9.2 7.5 0.11 12.6 0.4 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3593) p450 PF00067.22 OAG35801.1 - 3.1e-64 217.4 0.0 3.8e-64 217.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short_C2 PF13561.6 OAG35802.1 - 5.8e-53 179.8 0.4 1.8e-52 178.3 0.4 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG35802.1 - 1.8e-45 154.8 0.1 3.6e-45 153.8 0.1 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG35802.1 - 7.2e-09 35.8 0.2 1.1e-08 35.2 0.2 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OAG35802.1 - 7.4e-05 22.0 0.0 0.00012 21.4 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 OAG35802.1 - 0.00094 18.7 0.7 0.0016 17.9 0.7 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OAG35802.1 - 0.019 14.0 0.0 0.035 13.1 0.0 1.4 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_25 PF13649.6 OAG35802.1 - 0.051 14.3 0.0 0.3 11.8 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Sacchrp_dh_NADP PF03435.18 OAG35802.1 - 0.06 13.6 0.1 0.11 12.8 0.1 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Methyltransf_33 PF10017.9 OAG35802.1 - 0.14 11.2 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent MFS_1 PF07690.16 OAG35803.1 - 1.2e-31 109.9 33.2 1.2e-31 109.9 33.2 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF4184 PF13803.6 OAG35803.1 - 0.28 10.9 5.8 0.077 12.7 0.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4184) OATP PF03137.20 OAG35803.1 - 1.5 7.0 8.1 0.16 10.3 1.7 2.3 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Epimerase PF01370.21 OAG35804.1 - 1.3e-17 64.1 0.0 2.7e-17 63.0 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 OAG35804.1 - 3.4e-10 40.1 1.7 5.1e-10 39.5 1.7 1.3 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 OAG35804.1 - 3.1e-08 33.4 0.1 4.7e-06 26.2 0.1 2.6 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 OAG35804.1 - 3.5e-08 33.3 0.1 4.1e-07 29.8 0.5 1.9 2 0 0 2 2 2 1 NmrA-like family 3Beta_HSD PF01073.19 OAG35804.1 - 3.9e-07 29.3 0.0 7e-07 28.5 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 OAG35804.1 - 3.2e-05 23.2 0.0 5.6e-05 22.4 0.0 1.4 1 1 0 1 1 1 1 RmlD substrate binding domain Sacchrp_dh_NADP PF03435.18 OAG35804.1 - 6.9e-05 23.1 0.1 0.00013 22.2 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_4 PF07993.12 OAG35804.1 - 0.00035 19.8 0.0 0.0013 17.9 0.0 1.9 2 0 0 2 2 2 1 Male sterility protein adh_short PF00106.25 OAG35804.1 - 0.0018 17.8 0.2 0.0032 16.9 0.1 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG35804.1 - 0.0052 16.7 0.8 0.015 15.2 0.8 1.7 1 1 0 1 1 1 1 KR domain TrkA_N PF02254.18 OAG35804.1 - 0.0082 16.4 0.1 0.015 15.6 0.1 1.4 1 0 0 1 1 1 1 TrkA-N domain OAM_dimer PF16554.5 OAG35804.1 - 0.032 14.7 0.6 0.096 13.1 0.3 1.8 2 0 0 2 2 2 0 Dimerisation domain of d-ornithine 4,5-aminomutase ApbA PF02558.16 OAG35804.1 - 0.13 11.9 0.1 0.26 10.9 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA SIR2 PF02146.17 OAG35806.1 - 3.6e-32 111.7 0.0 1.9e-12 47.5 0.0 3.2 3 0 0 3 3 3 3 Sir2 family zinc_ribbon_4 PF13717.6 OAG35806.1 - 0.022 14.6 1.7 0.04 13.9 0.6 1.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-trcl PF13451.6 OAG35806.1 - 0.073 13.0 3.1 0.15 11.9 3.1 1.5 1 0 0 1 1 1 0 Probable zinc-ribbon domain Isochorismatase PF00857.20 OAG35806.1 - 0.094 12.9 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Isochorismatase family DHBP_synthase PF00926.19 OAG35807.1 - 1.6e-83 279.0 0.1 1.9e-83 278.7 0.1 1.1 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase UPF0154 PF03672.13 OAG35808.1 - 1.9 8.6 5.0 1.1 9.3 3.2 1.6 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0154) DUF3149 PF11346.8 OAG35808.1 - 6.6 6.4 6.5 10 5.8 6.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) TFA2_Winged_2 PF18121.1 OAG35809.1 - 7e-22 76.9 0.6 3.8e-21 74.6 0.1 2.1 2 0 0 2 2 2 1 TFA2 Winged helix domain 2 TFIIE_beta PF02186.15 OAG35809.1 - 2.3e-06 27.8 0.4 1.1e-05 25.6 0.0 2.2 2 1 0 2 2 2 1 TFIIE beta subunit core domain Rx_N PF18052.1 OAG35809.1 - 0.094 13.0 0.8 0.24 11.7 0.4 1.8 1 1 0 1 1 1 0 Rx N-terminal domain APG6_N PF17675.1 OAG35809.1 - 0.1 13.1 0.1 0.21 12.1 0.1 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region TPR_MLP1_2 PF07926.12 OAG35810.1 - 2.9e-32 111.4 29.1 2.9e-32 111.4 29.1 18.9 8 7 8 16 16 16 2 TPR/MLP1/MLP2-like protein Uteroglobin PF01099.17 OAG35810.1 - 0.023 15.0 0.2 0.023 15.0 0.2 5.4 7 0 0 7 7 7 0 Uteroglobin family Mto2_bdg PF12808.7 OAG35810.1 - 0.052 13.8 0.2 0.052 13.8 0.2 15.0 16 2 3 19 19 19 0 Micro-tubular organiser Mto1 C-term Mto2-binding region p450 PF00067.22 OAG35811.1 - 1.9e-70 238.0 0.0 2.3e-70 237.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.25 OAG35812.1 - 2.9e-38 131.3 0.0 4.2e-38 130.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG35812.1 - 3.1e-31 108.7 0.0 6.3e-31 107.7 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG35812.1 - 0.00047 20.1 0.2 0.0016 18.4 0.1 1.9 2 1 0 2 2 2 1 KR domain TrkA_N PF02254.18 OAG35812.1 - 0.00048 20.4 0.0 0.00088 19.5 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain Epimerase PF01370.21 OAG35812.1 - 0.0014 18.1 0.0 0.0032 17.0 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family DFP PF04127.15 OAG35812.1 - 0.0052 16.6 0.1 0.01 15.7 0.1 1.4 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein NAD_binding_10 PF13460.6 OAG35812.1 - 0.0067 16.3 0.0 0.0096 15.8 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding 3HCDH_N PF02737.18 OAG35812.1 - 0.06 13.2 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 OAG35812.1 - 0.079 13.2 0.0 0.18 12.1 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain TSP_NTD PF17804.1 OAG35812.1 - 0.17 12.2 0.0 0.26 11.5 0.0 1.2 1 0 0 1 1 1 0 Tail specific protease N-terminal domain Pyr_redox_2 PF07992.14 OAG35813.1 - 6.4e-11 42.0 0.0 1.1e-07 31.4 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG35813.1 - 1e-09 38.1 0.0 1.5e-07 31.0 0.0 3.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 OAG35813.1 - 2.9e-06 26.0 0.0 1.3e-05 23.8 0.0 2.0 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Shikimate_DH PF01488.20 OAG35813.1 - 4.6e-06 26.7 0.1 0.0042 17.1 0.0 2.3 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase K_oxygenase PF13434.6 OAG35813.1 - 0.00025 20.3 0.0 0.032 13.4 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 OAG35813.1 - 0.00027 21.1 0.0 0.0012 19.0 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAG35813.1 - 0.0027 17.3 1.4 0.76 9.3 0.0 2.6 2 0 0 2 2 2 2 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.19 OAG35813.1 - 0.013 14.9 0.0 0.029 13.7 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 OAG35813.1 - 0.014 14.5 0.1 0.024 13.7 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain FAD_binding_3 PF01494.19 OAG35813.1 - 0.02 14.2 0.7 3 7.0 1.2 2.3 2 0 0 2 2 2 0 FAD binding domain NAD_binding_9 PF13454.6 OAG35813.1 - 0.081 12.9 0.2 8.1 6.4 0.1 2.9 3 0 0 3 3 3 0 FAD-NAD(P)-binding NAD_binding_7 PF13241.6 OAG35813.1 - 0.18 12.3 0.0 4.8 7.7 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding F420_oxidored PF03807.17 OAG35813.1 - 0.44 11.2 1.4 32 5.2 0.0 2.7 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Ammonium_transp PF00909.21 OAG35814.1 - 1.1e-106 356.9 30.7 1.4e-106 356.6 30.7 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family UQ_con PF00179.26 OAG35815.1 - 4.2e-21 75.1 0.0 5.8e-21 74.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OAG35815.1 - 0.0014 18.3 0.2 0.064 13.0 0.2 2.5 1 1 0 1 1 1 1 Prokaryotic E2 family B MA3 PF02847.17 OAG35816.1 - 5e-29 100.6 0.2 1.3e-28 99.2 0.1 1.8 2 0 0 2 2 2 1 MA3 domain MIF4G PF02854.19 OAG35816.1 - 4.2e-13 49.4 0.1 8e-13 48.5 0.1 1.5 1 0 0 1 1 1 1 MIF4G domain CDC45 PF02724.14 OAG35816.1 - 0.05 11.9 4.9 3 6.0 7.0 2.3 2 0 0 2 2 2 0 CDC45-like protein Baculo_p26 PF04766.12 OAG35817.1 - 0.018 14.5 0.0 0.035 13.6 0.0 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus p26 protein PFK PF00365.20 OAG35818.1 - 5.1e-182 603.5 0.0 4.2e-101 338.0 0.2 2.1 2 0 0 2 2 2 2 Phosphofructokinase CPSF_A PF03178.15 OAG35819.1 - 5.2e-91 305.3 0.0 7.2e-90 301.6 0.0 2.1 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.9 OAG35819.1 - 4.2e-26 91.7 0.0 7.6e-26 90.8 0.0 1.4 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term LMBR1 PF04791.16 OAG35820.1 - 4.2e-17 62.2 26.7 2e-16 60.0 8.9 2.3 1 1 1 2 2 2 2 LMBR1-like membrane protein DUF1673 PF07895.11 OAG35820.1 - 0.89 9.2 22.0 0.01 15.6 4.8 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1673) SUIM_assoc PF16619.5 OAG35821.1 - 0.015 15.3 10.0 0.037 14.1 7.5 2.3 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 MSA-2c PF12238.8 OAG35821.1 - 5.1 7.0 9.3 9 6.2 9.3 1.3 1 0 0 1 1 1 0 Merozoite surface antigen 2c APH PF01636.23 OAG35822.1 - 5.6e-07 29.7 0.0 1.8e-06 28.1 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family WD40 PF00400.32 OAG35824.1 - 2.5e-07 31.3 1.1 0.35 11.8 0.0 4.7 4 0 0 4 4 4 4 WD domain, G-beta repeat DUF1770 PF08589.10 OAG35824.1 - 0.04 14.9 1.7 0.096 13.7 0.2 2.2 2 0 0 2 2 2 0 Fungal protein of unknown function (DUF1770) Fungal_trans_2 PF11951.8 OAG35825.1 - 7.2e-09 34.9 2.5 1.1e-08 34.3 2.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain NDUF_B4 PF07225.12 OAG35825.1 - 0.13 12.2 0.0 0.48 10.3 0.0 1.9 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) APG6 PF04111.12 OAG35826.1 - 7.3e-69 231.3 0.0 1.5e-68 230.2 0.0 1.6 1 0 0 1 1 1 1 Apg6 BARA domain APG6_N PF17675.1 OAG35826.1 - 3e-15 56.9 6.4 1e-14 55.2 6.4 2.0 1 1 0 1 1 1 1 Apg6 coiled-coil region CdvA PF18822.1 OAG35826.1 - 0.054 13.3 3.6 0.054 13.3 1.9 1.9 2 1 0 2 2 2 0 CdvA-like coiled-coil domain CCDC-167 PF15188.6 OAG35826.1 - 0.16 12.4 3.6 0.48 10.8 3.6 1.9 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 Scm3 PF10384.9 OAG35827.1 - 8.9e-19 67.0 4.6 5.7e-18 64.4 0.3 2.9 3 0 0 3 3 3 1 Centromere protein Scm3 Rhabdo_M1 PF03342.13 OAG35827.1 - 0.083 12.2 0.0 5.2 6.4 0.0 2.3 2 0 0 2 2 2 0 Rhabdovirus M1 matrix protein (M1 polymerase-associated protein) PALP PF00291.25 OAG35828.1 - 3e-65 220.6 0.2 3.7e-65 220.3 0.2 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme UPF0181 PF03701.14 OAG35828.1 - 0.093 12.4 0.2 0.65 9.7 0.0 2.4 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0181) Methyltransf_28 PF02636.17 OAG35829.1 - 2.4e-39 135.6 0.0 3.6e-39 135.0 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PRMT5 PF05185.16 OAG35829.1 - 0.18 11.6 0.0 0.38 10.6 0.0 1.5 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase P34-Arc PF04045.14 OAG35830.1 - 2.8e-106 354.6 0.3 3.4e-106 354.3 0.3 1.0 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc ARPC4 PF05856.12 OAG35830.1 - 0.00034 20.3 0.9 0.0013 18.4 0.5 2.1 2 1 0 2 2 2 1 ARP2/3 complex 20 kDa subunit (ARPC4) Hemerythrin PF01814.23 OAG35830.1 - 0.27 11.9 2.2 7.5 7.2 0.5 2.4 2 0 0 2 2 2 0 Hemerythrin HHE cation binding domain NAD_binding_1 PF00175.21 OAG35831.1 - 4.2e-15 56.3 0.0 7.5e-15 55.5 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Globin PF00042.22 OAG35831.1 - 5e-11 43.1 0.1 3.6e-10 40.4 0.1 2.4 3 0 0 3 3 3 1 Globin FAD_binding_6 PF00970.24 OAG35831.1 - 1.8e-06 28.2 0.0 3e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Protoglobin PF11563.8 OAG35831.1 - 3.7e-06 26.9 0.2 6.8e-06 26.1 0.2 1.3 1 0 0 1 1 1 1 Protoglobin NAD_binding_6 PF08030.12 OAG35831.1 - 1.7e-05 25.0 0.0 0.00071 19.7 0.0 2.3 2 0 0 2 2 2 1 Ferric reductase NAD binding domain DNA_primase_lrg PF04104.14 OAG35832.1 - 1.2e-87 293.7 0.0 2.5e-87 292.7 0.0 1.5 2 0 0 2 2 2 1 Eukaryotic and archaeal DNA primase, large subunit ADK PF00406.22 OAG35833.1 - 1.9e-35 122.2 0.0 3e-20 72.9 0.0 2.1 2 0 0 2 2 2 2 Adenylate kinase AAA_17 PF13207.6 OAG35833.1 - 1.3e-15 58.1 0.1 1.9e-10 41.3 0.0 2.5 2 1 0 3 3 3 2 AAA domain ADK_lid PF05191.14 OAG35833.1 - 2e-15 56.4 0.0 3.3e-15 55.8 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 OAG35833.1 - 4e-05 24.2 0.0 0.00011 22.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 OAG35833.1 - 0.00091 19.4 0.2 0.002 18.3 0.0 1.9 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.6 OAG35833.1 - 0.066 13.5 0.0 0.18 12.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain DUF1654 PF07867.11 OAG35833.1 - 0.14 11.9 0.1 0.27 11.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1654) AAA PF00004.29 OAG35833.1 - 0.16 12.4 0.0 1.7 9.0 0.0 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MeaB PF03308.16 OAG35833.1 - 0.17 10.9 0.0 0.28 10.1 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Glyco_transf_41 PF13844.6 OAG35834.1 - 8.2e-91 304.8 0.1 1.3e-43 149.1 0.0 3.8 3 1 0 3 3 3 2 Glycosyl transferase family 41 TPR_1 PF00515.28 OAG35834.1 - 2.1e-18 65.3 5.1 7.4e-05 22.4 0.1 5.5 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 OAG35834.1 - 3.4e-17 61.1 5.6 0.0024 17.8 0.1 5.8 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.6 OAG35834.1 - 2.2e-12 46.7 9.7 0.00089 19.9 0.3 6.0 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 OAG35834.1 - 1.3e-11 43.8 3.5 0.029 14.6 0.0 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 OAG35834.1 - 3.4e-11 42.6 12.7 0.00031 20.3 0.4 6.0 5 1 2 7 7 7 3 TPR repeat TPR_12 PF13424.6 OAG35834.1 - 3.6e-10 40.0 9.1 0.00079 19.7 0.2 4.7 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 OAG35834.1 - 4e-09 36.1 13.4 0.018 14.9 0.6 5.9 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 OAG35834.1 - 8.5e-08 32.7 15.1 0.00016 22.2 1.1 4.8 4 2 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 OAG35834.1 - 1.2e-07 31.6 9.9 0.56 10.7 0.1 5.4 5 0 0 5 5 4 4 Tetratricopeptide repeat TPR_19 PF14559.6 OAG35834.1 - 1.7e-07 31.6 5.4 0.0027 18.2 2.2 3.4 2 2 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 OAG35834.1 - 2e-07 30.5 9.7 0.015 15.3 0.1 5.7 6 0 0 6 6 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 OAG35834.1 - 0.037 14.3 6.0 0.096 12.9 0.3 3.7 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 BTAD PF03704.17 OAG35834.1 - 0.33 11.4 0.0 0.33 11.4 0.0 4.0 4 0 0 4 4 4 0 Bacterial transcriptional activator domain TPR_6 PF13174.6 OAG35834.1 - 1.1 10.0 4.8 60 4.6 0.1 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat Myb_DNA-binding PF00249.31 OAG35835.1 - 2.5e-25 88.4 2.7 9.9e-15 54.5 0.2 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OAG35835.1 - 1.7e-19 69.8 1.7 7.2e-14 51.8 0.1 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain DUF2774 PF11242.8 OAG35835.1 - 0.051 13.8 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2774) HTH_23 PF13384.6 OAG35835.1 - 0.092 12.6 0.1 0.22 11.3 0.1 1.6 1 0 0 1 1 1 0 Homeodomain-like domain WD40 PF00400.32 OAG35836.1 - 1.1e-46 155.9 36.6 4.2e-05 24.2 0.0 12.7 12 1 0 12 12 11 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG35836.1 - 1.8e-21 76.2 4.9 0.0016 18.7 0.1 9.4 5 2 4 10 10 10 7 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 OAG35836.1 - 7.9e-17 61.5 0.1 1.5e-16 60.6 0.1 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family Ge1_WD40 PF16529.5 OAG35836.1 - 1.9e-07 30.4 12.7 0.32 9.9 0.3 6.2 5 2 2 7 7 7 4 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 OAG35836.1 - 0.00013 20.8 12.4 0.78 8.3 0.2 5.9 5 2 1 6 6 6 2 Nucleoporin Nup120/160 WD40_like PF17005.5 OAG35836.1 - 0.0002 20.8 0.0 0.28 10.5 0.0 3.5 3 1 1 4 4 4 1 WD40-like domain Nucleoporin_N PF08801.11 OAG35836.1 - 0.00021 20.1 2.1 0.53 9.0 0.0 4.5 3 2 1 6 6 6 2 Nup133 N terminal like eIF2A PF08662.11 OAG35836.1 - 0.00066 19.6 0.1 2 8.3 0.0 5.2 4 2 2 6 6 6 1 Eukaryotic translation initiation factor eIF2A Frtz PF11768.8 OAG35836.1 - 0.004 15.5 0.2 0.11 10.7 0.0 3.0 3 0 0 3 3 3 1 WD repeat-containing and planar cell polarity effector protein Fritz Utp13 PF08625.11 OAG35836.1 - 0.028 14.3 0.0 0.067 13.1 0.0 1.6 1 0 0 1 1 1 0 Utp13 specific WD40 associated domain Hira PF07569.11 OAG35836.1 - 0.057 13.1 0.3 5.8 6.6 0.1 3.4 2 1 0 2 2 2 0 TUP1-like enhancer of split PALB2_WD40 PF16756.5 OAG35836.1 - 0.076 11.9 1.8 2.8 6.8 0.3 3.2 4 0 0 4 4 4 0 Partner and localizer of BRCA2 WD40 domain Cys_Met_Meta_PP PF01053.20 OAG35837.1 - 1.5e-135 451.6 0.0 1.7e-135 451.4 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 OAG35837.1 - 6.9e-08 31.8 0.3 3.2e-07 29.6 0.2 1.9 2 0 0 2 2 2 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 OAG35837.1 - 3.5e-06 26.4 0.1 5e-06 25.9 0.1 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 OAG35837.1 - 9.8e-06 25.1 0.2 2.5e-05 23.8 0.2 1.6 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 OAG35837.1 - 2e-05 24.1 0.0 3.9e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.11 OAG35837.1 - 0.00014 20.6 0.0 0.00019 20.1 0.0 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase SepSecS PF05889.13 OAG35837.1 - 0.00017 20.4 0.0 0.00025 19.9 0.0 1.1 1 0 0 1 1 1 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Asparaginase_C PF17763.1 OAG35837.1 - 0.071 13.3 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 Glutaminase/Asparaginase C-terminal domain GDC-P PF02347.16 OAG35837.1 - 0.086 11.7 0.0 0.12 11.2 0.0 1.1 1 0 0 1 1 1 0 Glycine cleavage system P-protein AA_kinase PF00696.28 OAG35838.1 - 6.7e-33 114.3 0.5 1.2e-32 113.5 0.0 1.6 2 0 0 2 2 2 1 Amino acid kinase family ACT PF01842.25 OAG35838.1 - 1.6e-11 43.8 2.1 1.3e-08 34.5 0.3 3.0 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.6 OAG35838.1 - 4e-09 36.1 1.8 4e-09 36.1 1.8 2.5 3 0 0 3 3 3 1 ACT domain Abhydrolase_1 PF00561.20 OAG35839.1 - 3.9e-41 141.4 0.0 6e-41 140.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG35839.1 - 9.5e-05 23.1 3.2 0.00017 22.3 3.2 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 OAG35839.1 - 0.0037 17.4 0.0 0.0078 16.3 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein CN_hydrolase PF00795.22 OAG35840.1 - 2.4e-56 191.0 0.0 2.8e-56 190.8 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase CSS-motif PF12792.7 OAG35840.1 - 0.16 11.4 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 CSS motif domain associated with EAL Fungal_trans PF04082.18 OAG35841.1 - 3.4e-05 23.0 0.7 7e-05 22.0 0.7 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Acetyltransf_10 PF13673.7 OAG35842.1 - 9.7e-08 32.0 0.0 1.7e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OAG35842.1 - 5.1e-07 30.0 0.0 9.9e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAG35842.1 - 1.9e-05 24.9 0.0 2.6e-05 24.5 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 OAG35842.1 - 0.041 13.8 0.0 0.074 13.0 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_9 PF13527.7 OAG35842.1 - 0.049 13.7 0.0 11 6.1 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain DIOX_N PF14226.6 OAG35843.1 - 5.3e-14 53.0 0.0 9.4e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OAG35843.1 - 8.8e-12 45.4 0.0 1.5e-11 44.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Sugar_tr PF00083.24 OAG35844.1 - 5.6e-30 104.6 27.7 5.2e-21 75.0 7.9 2.2 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 OAG35844.1 - 3.5e-18 65.7 41.0 1.1e-09 37.7 21.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ATG22 PF11700.8 OAG35844.1 - 0.13 10.9 11.2 0.094 11.3 1.1 2.7 3 0 0 3 3 3 0 Vacuole effluxer Atg22 like DUF2070 PF09843.9 OAG35844.1 - 1.5 7.1 6.2 2.5 6.3 6.2 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) BT1 PF03092.16 OAG35844.1 - 2 6.5 5.8 0.79 7.9 0.6 2.2 2 0 0 2 2 2 0 BT1 family MFS_1 PF07690.16 OAG35845.1 - 1.9e-09 36.9 44.9 1.7e-08 33.8 44.3 2.5 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 OAG35845.1 - 5.1e-07 28.5 21.1 6.4e-07 28.2 21.1 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF4381 PF14316.6 OAG35845.1 - 5.7 7.2 7.9 9.2 6.5 0.3 3.7 2 2 1 3 3 3 0 Domain of unknown function (DUF4381) ADC PF06314.11 OAG35846.1 - 5.9e-32 111.1 0.0 7.2e-32 110.8 0.0 1.0 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) Xan_ur_permease PF00860.20 OAG35847.1 - 4.6e-26 91.4 36.0 1e-24 87.0 33.1 3.0 2 1 0 2 2 2 2 Permease family 4HBT_3 PF13622.6 OAG35848.1 - 3.9e-48 164.9 3.3 4.5e-48 164.7 3.3 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 OAG35848.1 - 0.0067 16.3 0.0 0.021 14.7 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA thioesterase Arteri_env PF01606.16 OAG35848.1 - 0.04 13.8 0.0 0.081 12.8 0.0 1.4 1 0 0 1 1 1 0 Arterivirus envelope protein SGL PF08450.12 OAG35849.1 - 6.5e-10 39.0 0.6 4.8e-07 29.6 0.1 2.5 2 0 0 2 2 2 2 SMP-30/Gluconolactonase/LRE-like region Acyl-CoA_dh_1 PF00441.24 OAG35850.1 - 1.1e-15 58.1 0.1 3.4e-15 56.5 0.0 1.9 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain AidB_N PF18158.1 OAG35850.1 - 5.9e-14 52.3 0.0 1e-13 51.5 0.0 1.4 1 0 0 1 1 1 1 Adaptive response protein AidB N-terminal domain Acyl-CoA_dh_M PF02770.19 OAG35850.1 - 4.9e-11 42.7 0.0 1.5e-10 41.1 0.0 1.9 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain DUF21 PF01595.20 OAG35850.1 - 0.11 12.2 0.0 0.32 10.7 0.1 1.6 2 0 0 2 2 2 0 Cyclin M transmembrane N-terminal domain AMP-binding PF00501.28 OAG35851.1 - 2.3e-41 141.8 0.0 3.7e-41 141.1 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Fungal_trans PF04082.18 OAG35851.1 - 2.2e-14 53.1 0.0 5.6e-14 51.8 0.0 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain AMP-binding_C PF13193.6 OAG35851.1 - 7.5e-05 23.6 0.0 0.00017 22.5 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 OAG35851.1 - 0.0058 16.5 0.0 0.024 14.6 0.0 2.1 1 1 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus DUF2957 PF11170.8 OAG35851.1 - 0.018 13.9 0.0 0.033 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2957) AA_permease_2 PF13520.6 OAG35852.1 - 3e-45 154.8 42.3 3.6e-45 154.6 42.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAG35852.1 - 1.6e-14 53.4 38.4 2e-14 53.1 38.4 1.1 1 0 0 1 1 1 1 Amino acid permease Amino_oxidase PF01593.24 OAG35853.1 - 1.6e-53 182.6 0.3 2e-53 182.3 0.3 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OAG35853.1 - 7.7e-11 42.1 0.2 1.6e-10 41.0 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAG35853.1 - 1.8e-08 34.4 0.0 9.9e-06 25.4 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_oxidored PF12831.7 OAG35853.1 - 1.8e-06 27.6 0.0 4.4e-06 26.3 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 OAG35853.1 - 9.9e-06 25.0 0.0 1.7e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 OAG35853.1 - 1.9e-05 23.9 0.1 3.3e-05 23.1 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 OAG35853.1 - 5.2e-05 22.6 0.0 0.0015 17.9 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAG35853.1 - 0.00062 18.6 0.0 0.0016 17.2 0.0 1.6 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 OAG35853.1 - 0.00083 18.5 0.1 0.0021 17.2 0.0 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 OAG35853.1 - 0.0043 16.2 0.0 0.014 14.5 0.0 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 OAG35853.1 - 0.012 14.9 0.0 2.4 7.3 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 OAG35853.1 - 0.013 14.8 0.2 0.023 14.0 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 OAG35853.1 - 0.025 15.1 0.0 0.12 13.0 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase VWA_CoxE PF05762.14 OAG35853.1 - 0.094 12.1 0.2 0.46 9.8 0.0 2.2 3 0 0 3 3 3 0 VWA domain containing CoxE-like protein Fungal_trans_2 PF11951.8 OAG35854.1 - 5.3e-21 74.9 0.5 3e-14 52.7 0.0 2.1 1 1 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG35854.1 - 2.3e-07 30.8 10.4 3.9e-07 30.1 10.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ldh_1_N PF00056.23 OAG35855.1 - 2.7e-30 105.3 0.0 3.9e-30 104.8 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 OAG35855.1 - 2.6e-19 69.7 0.0 4.3e-19 69.1 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain F420_oxidored PF03807.17 OAG35855.1 - 0.00023 21.7 0.1 0.0008 19.9 0.1 2.0 1 1 1 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 OAG35855.1 - 0.0017 18.0 0.2 0.021 14.5 0.2 2.4 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Sacchrp_dh_NADP PF03435.18 OAG35855.1 - 0.0035 17.6 0.1 0.024 14.9 0.1 2.3 2 1 1 3 3 3 1 Saccharopine dehydrogenase NADP binding domain UDPG_MGDP_dh_N PF03721.14 OAG35855.1 - 0.015 14.9 0.1 0.031 13.8 0.1 1.6 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_Gly3P_dh_N PF01210.23 OAG35855.1 - 0.016 15.2 0.0 0.2 11.6 0.0 2.3 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DAO PF01266.24 OAG35855.1 - 0.029 14.0 2.6 0.15 11.6 0.3 2.2 1 1 1 2 2 2 0 FAD dependent oxidoreductase ThiF PF00899.21 OAG35855.1 - 0.044 13.1 0.2 0.09 12.1 0.0 1.5 2 0 0 2 2 2 0 ThiF family 2-Hacid_dh_C PF02826.19 OAG35855.1 - 0.064 12.6 0.0 0.16 11.3 0.0 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PglD_N PF17836.1 OAG35855.1 - 0.077 13.6 0.0 0.21 12.2 0.0 1.8 1 0 0 1 1 1 0 PglD N-terminal domain 3HCDH_N PF02737.18 OAG35855.1 - 0.1 12.5 0.1 0.17 11.8 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF3328 PF11807.8 OAG35856.1 - 1.2e-44 152.7 0.1 1.4e-44 152.5 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF4456 PF14644.6 OAG35856.1 - 0.013 15.2 0.0 0.02 14.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4456) HDPD PF02924.14 OAG35857.1 - 0.098 12.8 0.3 0.098 12.8 0.3 2.0 2 1 0 2 2 2 0 Bacteriophage lambda head decoration protein D PTR2 PF00854.21 OAG35858.1 - 1.2e-63 215.3 3.5 1.7e-63 214.8 3.5 1.1 1 0 0 1 1 1 1 POT family DUF4149 PF13664.6 OAG35858.1 - 1.2 9.5 6.0 7.3 7.0 0.2 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF4149) ACOX PF01756.19 OAG35859.1 - 1e-47 162.0 1.4 2.3e-47 160.9 0.8 1.8 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 OAG35859.1 - 4e-28 98.5 1.3 3.4e-27 95.5 0.2 2.5 2 0 0 2 2 2 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 OAG35859.1 - 3.1e-14 53.0 0.0 1.1e-13 51.1 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 OAG35859.1 - 4.2e-06 27.0 0.2 0.0058 16.9 0.0 2.6 2 0 0 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain DAGK_cat PF00781.24 OAG35860.1 - 7.7e-23 80.5 0.1 1.3e-22 79.7 0.1 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Pkinase PF00069.25 OAG35861.1 - 1.8e-67 227.5 0.0 2.8e-67 226.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG35861.1 - 5.1e-36 124.3 0.0 9.6e-35 120.1 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAG35861.1 - 0.00011 21.6 0.1 0.00038 19.9 0.1 1.8 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 OAG35861.1 - 0.0015 18.5 0.0 0.0035 17.3 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 OAG35861.1 - 0.0089 15.1 0.0 0.016 14.3 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Pkinase_fungal PF17667.1 OAG35861.1 - 0.02 13.7 0.0 0.038 12.8 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Ammonium_transp PF00909.21 OAG35862.1 - 6.7e-119 397.1 30.3 7.6e-119 397.0 30.3 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DUF441 PF04284.13 OAG35862.1 - 0.059 13.4 2.8 0.13 12.3 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF441) Atrophin-1 PF03154.15 OAG35863.1 - 4.8 5.3 14.7 5.8 5.1 14.7 1.1 1 0 0 1 1 1 0 Atrophin-1 family Kelch_5 PF13854.6 OAG35864.1 - 4.9e-10 39.2 0.3 4.9e-10 39.2 0.3 3.7 4 0 0 4 4 4 1 Kelch motif Kelch_3 PF13415.6 OAG35864.1 - 1.5e-05 25.2 7.9 0.05 13.9 0.2 4.6 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_6 PF13964.6 OAG35864.1 - 0.00052 20.2 4.1 2.3 8.6 0.1 4.2 3 0 0 3 3 3 2 Kelch motif DUF4448 PF14610.6 OAG35864.1 - 0.0035 17.2 0.0 0.0061 16.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Kelch_2 PF07646.15 OAG35864.1 - 0.033 14.2 3.1 0.23 11.5 0.3 3.5 3 0 0 3 3 3 0 Kelch motif Kelch_1 PF01344.25 OAG35864.1 - 0.049 13.2 0.4 0.049 13.2 0.4 5.0 5 1 0 5 5 5 0 Kelch motif Kelch_4 PF13418.6 OAG35864.1 - 0.052 13.6 12.4 0.2 11.7 0.2 4.1 5 0 0 5 5 5 0 Galactose oxidase, central domain Alpha_GJ PF03229.13 OAG35864.1 - 0.54 10.8 7.2 0.077 13.6 1.5 2.5 2 1 0 2 2 2 0 Alphavirus glycoprotein J RRM_1 PF00076.22 OAG35865.1 - 1.3e-15 57.0 0.1 5.3e-07 29.4 0.0 3.0 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OAG35865.1 - 0.065 13.1 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Occluded RNA-recognition motif Mpv17_PMP22 PF04117.12 OAG35868.1 - 6e-21 74.4 0.1 1.3e-20 73.3 0.1 1.6 1 0 0 1 1 1 1 Mpv17 / PMP22 family PGK PF00162.19 OAG35869.1 - 4.5e-151 503.1 0.5 5.1e-151 502.9 0.5 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase PA PF02225.22 OAG35869.1 - 0.0065 16.5 0.3 0.6 10.2 0.0 2.9 2 0 0 2 2 2 1 PA domain DUF3808 PF10300.9 OAG35870.1 - 4.4e-138 461.0 0.0 1.2e-137 459.6 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3808) Acetyltransf_1 PF00583.25 OAG35871.1 - 6.1e-13 49.0 0.0 7.4e-13 48.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OAG35871.1 - 8e-09 35.8 0.0 1.2e-08 35.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OAG35871.1 - 7.8e-08 32.3 0.0 9e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAG35871.1 - 0.0013 18.6 0.0 0.0026 17.7 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 OAG35871.1 - 0.015 15.4 0.0 0.023 14.8 0.0 1.2 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase ELFV_dehydrog PF00208.21 OAG35872.1 - 1.1e-83 280.7 4.0 1.4e-83 280.4 4.0 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 OAG35872.1 - 3.2e-43 146.7 0.0 9.8e-43 145.1 0.0 1.8 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Nup160 PF11715.8 OAG35873.1 - 1.8e-103 347.1 2.7 2.4e-103 346.6 2.7 1.1 1 0 0 1 1 1 1 Nucleoporin Nup120/160 FF PF01846.19 OAG35874.1 - 3.9e-50 167.8 18.5 5e-15 55.4 0.8 7.3 6 1 0 6 6 6 6 FF domain WW PF00397.26 OAG35874.1 - 5.1e-17 61.7 19.6 1.7e-08 34.4 5.8 2.6 2 0 0 2 2 2 2 WW domain RhoGAP-FF1 PF16512.5 OAG35874.1 - 0.00037 21.1 13.8 0.38 11.4 0.4 4.8 3 1 1 4 4 4 3 p190-A and -B Rho GAPs FF domain PTPlike_phytase PF14566.6 OAG35874.1 - 4.9 7.3 12.8 0.023 14.8 2.0 2.6 3 0 0 3 3 3 0 Inositol hexakisphosphate Trs65 PF12735.7 OAG35875.1 - 6.2e-66 223.0 0.0 9.2e-66 222.4 0.0 1.3 1 0 0 1 1 1 1 TRAPP trafficking subunit Trs65 SIP1 PF04938.12 OAG35877.1 - 6.1e-09 35.9 0.0 8.5e-08 32.2 0.0 2.0 2 0 0 2 2 2 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) DUF485 PF04341.12 OAG35878.1 - 0.035 14.0 0.0 0.059 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF485 MtrG PF04210.13 OAG35878.1 - 0.041 13.7 0.0 0.079 12.8 0.0 1.4 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit G SnoaL_4 PF13577.6 OAG35879.1 - 0.071 13.2 0.0 0.14 12.3 0.0 1.5 1 1 0 1 1 1 0 SnoaL-like domain tRNA-synt_2 PF00152.20 OAG35880.1 - 1.7e-70 237.6 0.1 2.2e-70 237.2 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 OAG35880.1 - 6.9e-08 32.4 0.1 1.2e-07 31.6 0.1 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 OAG35880.1 - 0.018 14.6 0.4 3.8 6.9 0.0 2.4 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) CDPS PF16715.5 OAG35880.1 - 0.18 11.4 1.6 0.39 10.3 1.6 1.6 1 0 0 1 1 1 0 Cyclodipeptide synthase ISG65-75 PF11727.8 OAG35880.1 - 0.22 10.7 7.7 0.35 10.1 7.7 1.2 1 0 0 1 1 1 0 Invariant surface glycoprotein NARP1 PF12569.8 OAG35880.1 - 0.26 10.1 11.7 0.36 9.7 11.7 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Abhydrolase_6 PF12697.7 OAG35881.1 - 1.3e-05 25.9 1.4 2.2e-05 25.2 0.6 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family PGAP1 PF07819.13 OAG35881.1 - 0.00038 20.2 0.1 0.0011 18.7 0.1 1.7 1 1 1 2 2 2 1 PGAP1-like protein DUF676 PF05057.14 OAG35881.1 - 0.00042 19.9 0.0 0.00089 18.8 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) UPF0227 PF05728.12 OAG35881.1 - 0.023 14.7 1.2 0.36 10.7 0.0 2.8 3 1 0 3 3 3 0 Uncharacterised protein family (UPF0227) Lipase_3 PF01764.25 OAG35881.1 - 0.15 11.9 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) ALMT PF11744.8 OAG35881.1 - 8.1 5.2 8.6 13 4.4 8.6 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter PX PF00787.24 OAG35882.1 - 1.2e-15 57.5 0.0 6.1e-15 55.2 0.0 2.0 2 0 0 2 2 2 1 PX domain Prenyltrans PF00432.21 OAG35882.1 - 0.12 12.1 0.1 0.21 11.4 0.1 1.3 1 0 0 1 1 1 0 Prenyltransferase and squalene oxidase repeat Ku_PK_bind PF08785.11 OAG35883.1 - 2e-31 108.7 0.0 3.9e-31 107.7 0.0 1.5 1 0 0 1 1 1 1 Ku C terminal domain like Ku PF02735.16 OAG35883.1 - 4.9e-29 101.5 0.0 9.9e-29 100.5 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 OAG35883.1 - 9.4e-15 54.9 0.0 2e-14 53.9 0.0 1.6 1 1 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain VWA PF00092.28 OAG35883.1 - 1.7e-05 25.2 0.1 5.8e-05 23.4 0.1 1.9 2 0 0 2 2 2 1 von Willebrand factor type A domain Sugar_tr PF00083.24 OAG35884.1 - 4.7e-39 134.5 14.6 6.1e-39 134.1 14.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG35884.1 - 8.4e-31 107.2 28.7 8.4e-31 107.2 28.7 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily ATG22 PF11700.8 OAG35884.1 - 0.00045 19.0 4.1 0.0037 16.0 0.8 2.3 2 0 0 2 2 2 2 Vacuole effluxer Atg22 like FUN14 PF04930.15 OAG35884.1 - 0.29 11.6 2.0 0.54 10.7 0.5 2.3 2 0 0 2 2 2 0 FUN14 family p450 PF00067.22 OAG35885.1 - 3.9e-61 207.2 0.0 5.2e-61 206.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Cofilin_ADF PF00241.20 OAG35886.1 - 4.1e-23 81.5 0.0 6.8e-12 45.3 0.0 2.1 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein PHF5 PF03660.14 OAG35887.1 - 1.3e-52 176.3 9.5 1.5e-52 176.2 9.5 1.0 1 0 0 1 1 1 1 PHF5-like protein PolC_DP2 PF03833.13 OAG35887.1 - 0.34 8.7 6.5 0.36 8.6 6.5 1.2 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DZR PF12773.7 OAG35887.1 - 1.3 9.1 14.6 2.3 8.3 1.3 3.0 1 1 1 2 2 2 0 Double zinc ribbon Pinin_SDK_memA PF04696.13 OAG35888.1 - 3.8e-33 114.3 17.3 3.8e-33 114.3 17.3 2.8 2 1 1 3 3 3 1 pinin/SDK/memA/ protein conserved region Borrelia_P83 PF05262.11 OAG35888.1 - 0.3 9.5 20.5 0.44 9.0 20.5 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein OmpH PF03938.14 OAG35888.1 - 0.72 10.2 16.9 0.26 11.6 4.6 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Exo_endo_phos PF03372.23 OAG35889.1 - 2e-12 47.1 0.0 3.4e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DGOK PF05035.12 OAG35889.1 - 0.17 10.7 0.1 11 4.8 0.0 2.2 2 0 0 2 2 2 0 2-keto-3-deoxy-galactonokinase NHase_beta PF02211.15 OAG35890.1 - 0.056 13.5 3.5 0.063 13.3 3.5 1.1 1 0 0 1 1 1 0 Nitrile hydratase beta subunit FRG2 PF15315.6 OAG35890.1 - 0.41 10.8 6.5 0.71 10.1 6.2 1.6 1 1 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 Epimerase PF01370.21 OAG35892.1 - 2e-06 27.5 0.0 0.00029 20.4 0.0 2.3 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 OAG35892.1 - 0.00019 21.4 0.0 0.00032 20.7 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 OAG35892.1 - 0.0012 18.4 0.0 0.0019 17.8 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 OAG35892.1 - 0.028 14.7 0.0 0.048 13.9 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain GDP_Man_Dehyd PF16363.5 OAG35892.1 - 0.064 12.7 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase TPP_enzyme_M PF00205.22 OAG35892.1 - 0.12 12.1 0.0 0.43 10.3 0.0 1.8 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain 3Beta_HSD PF01073.19 OAG35892.1 - 0.18 10.7 0.0 0.72 8.8 0.0 1.8 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family ADH_zinc_N PF00107.26 OAG35893.1 - 4.8e-22 78.3 0.0 7.6e-22 77.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAG35893.1 - 1.1e-15 58.8 0.0 1.7e-15 58.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG35893.1 - 1.6e-08 34.4 0.0 5e-07 29.6 0.0 2.4 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain Rep_fac-A_C PF08646.10 OAG35894.1 - 1.7e-57 193.2 7.9 3e-55 186.0 3.7 2.5 2 0 0 2 2 2 2 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 OAG35894.1 - 2.9e-38 129.7 0.1 3e-37 126.5 0.1 2.4 2 0 0 2 2 2 1 Replication protein A OB domain Rep-A_N PF04057.12 OAG35894.1 - 6.3e-19 67.9 0.3 1.3e-18 66.9 0.3 1.5 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.25 OAG35894.1 - 1.6e-17 63.2 0.0 2.5e-10 40.2 0.0 3.8 3 0 0 3 3 3 3 OB-fold nucleic acid binding domain CDC24_OB3 PF17244.2 OAG35894.1 - 0.00016 21.5 0.1 0.011 15.5 0.0 3.0 3 0 0 3 3 3 1 Cell division control protein 24, OB domain 3 DUF4539 PF15072.6 OAG35894.1 - 0.11 12.5 0.1 6.4 6.9 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4539) DLH PF01738.18 OAG35895.1 - 5.2e-20 71.9 0.0 3.5e-10 39.8 0.0 2.4 2 1 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 OAG35895.1 - 0.0031 17.2 0.0 1.1 8.8 0.0 2.7 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAG35895.1 - 0.071 12.4 0.0 8.8 5.5 0.0 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 EF-hand_8 PF13833.6 OAG35896.1 - 1.6e-34 117.5 6.6 2.1e-15 56.3 0.6 3.2 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 OAG35896.1 - 5.1e-33 110.2 9.2 7e-10 37.7 0.9 4.1 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 OAG35896.1 - 6.2e-30 103.5 3.2 3.3e-19 69.1 2.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OAG35896.1 - 4.1e-22 76.2 6.4 7.2e-09 34.9 0.0 4.4 4 1 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 OAG35896.1 - 1.3e-19 68.7 6.3 9e-06 25.0 0.0 4.2 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.6 OAG35896.1 - 3e-13 49.9 0.4 5.2e-06 26.7 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 OAG35896.1 - 6.3e-08 32.5 1.3 0.00064 19.6 0.3 2.1 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand UPF0154 PF03672.13 OAG35896.1 - 5.6e-07 29.5 0.3 0.0043 17.1 0.1 3.0 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) SPARC_Ca_bdg PF10591.9 OAG35896.1 - 4.9e-06 26.8 0.1 0.0014 18.9 0.1 2.1 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EFhand_Ca_insen PF08726.10 OAG35896.1 - 7.8e-06 25.9 0.5 2e-05 24.6 0.2 1.8 2 0 0 2 2 2 1 Ca2+ insensitive EF hand EF-hand_11 PF08976.11 OAG35896.1 - 0.00012 22.9 0.2 0.0022 18.8 0.1 2.0 1 1 1 2 2 2 1 EF-hand domain RNA_pol_Rpb4 PF03874.16 OAG35896.1 - 0.00046 20.5 0.7 0.49 10.7 0.3 2.6 2 1 0 2 2 2 2 RNA polymerase Rpb4 TerB PF05099.13 OAG35896.1 - 0.0016 18.4 0.4 0.69 9.9 0.1 2.1 1 1 1 2 2 2 2 Tellurite resistance protein TerB SurA_N_2 PF13623.6 OAG35896.1 - 0.0048 16.8 0.7 0.27 11.1 0.1 2.2 1 1 1 2 2 2 1 SurA N-terminal domain DUF5580 PF17743.1 OAG35896.1 - 0.0049 15.5 0.0 0.0053 15.4 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5580) RuvA_C PF07499.13 OAG35896.1 - 0.047 14.2 0.1 7.7 7.1 0.0 3.0 3 0 0 3 3 3 0 RuvA, C-terminal domain Poly_export PF02563.16 OAG35896.1 - 0.048 13.9 0.0 0.18 12.0 0.0 2.0 2 1 0 2 2 2 0 Polysaccharide biosynthesis/export protein YqeY PF09424.10 OAG35896.1 - 0.065 13.3 0.8 0.45 10.6 0.2 2.0 1 1 0 2 2 2 0 Yqey-like protein dCache_2 PF08269.11 OAG35896.1 - 0.067 12.4 0.1 0.88 8.7 0.1 2.1 1 1 1 2 2 2 0 Cache domain Peptidase_M24 PF00557.24 OAG35896.1 - 0.082 12.6 0.0 2.6 7.7 0.0 2.2 1 1 0 2 2 2 0 Metallopeptidase family M24 Dockerin_1 PF00404.18 OAG35896.1 - 0.094 12.9 5.1 0.34 11.1 0.9 2.7 1 1 2 3 3 3 0 Dockerin type I domain DUF5132 PF17195.4 OAG35896.1 - 0.13 12.4 0.5 19 5.4 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF5132) SNARE PF05739.19 OAG35897.1 - 9.6e-16 57.5 0.5 4.9e-15 55.2 0.5 2.2 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.25 OAG35897.1 - 3.8e-06 26.7 11.9 2.4e-05 24.1 11.9 1.9 1 1 0 1 1 1 1 Syntaxin Med21 PF11221.8 OAG35897.1 - 0.00082 19.6 1.4 0.0078 16.5 0.1 2.4 2 0 0 2 2 2 1 Subunit 21 of Mediator complex MCPsignal PF00015.21 OAG35897.1 - 0.0029 17.4 8.4 0.016 15.0 0.3 2.2 2 0 0 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain MAP65_ASE1 PF03999.12 OAG35897.1 - 0.011 14.5 3.4 0.014 14.2 3.4 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) DNA_repr_REX1B PF14966.6 OAG35897.1 - 0.011 16.4 2.7 0.032 14.9 0.5 2.7 2 1 0 2 2 2 0 DNA repair REX1-B TMPIT PF07851.13 OAG35897.1 - 0.055 12.7 4.3 0.086 12.1 1.2 2.0 2 0 0 2 2 2 0 TMPIT-like protein BatA PF07584.11 OAG35897.1 - 0.17 12.3 2.2 0.37 11.2 2.2 1.5 1 0 0 1 1 1 0 Aerotolerance regulator N-terminal YajC PF02699.15 OAG35897.1 - 0.5 10.3 3.3 4.8 7.1 0.9 2.5 2 0 0 2 2 2 0 Preprotein translocase subunit SlyX PF04102.12 OAG35897.1 - 0.55 10.9 6.9 1.9 9.2 0.2 3.1 2 1 1 3 3 3 0 SlyX Syntaxin_2 PF14523.6 OAG35897.1 - 1.2 9.6 14.1 0.12 12.7 6.3 2.7 2 2 0 2 2 2 0 Syntaxin-like protein HET PF06985.11 OAG35898.1 - 5.7e-34 117.6 1.0 1.1e-33 116.6 1.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF815 PF05673.13 OAG35898.1 - 0.025 13.7 0.0 0.041 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Alpha_TIF PF02232.15 OAG35898.1 - 0.027 13.6 0.0 0.46 9.5 0.0 2.1 2 0 0 2 2 2 0 Alpha trans-inducing protein (Alpha-TIF) HeLo PF14479.6 OAG35899.1 - 8.6e-06 25.7 0.1 0.00023 21.1 0.0 2.3 1 1 1 2 2 2 2 Prion-inhibition and propagation CENP-T_C PF15511.6 OAG35900.1 - 4.4e-09 36.4 0.1 5.3e-09 36.2 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 OAG35900.1 - 1.9e-05 25.1 0.2 2.2e-05 24.8 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 OAG35900.1 - 5e-05 23.4 0.2 7.3e-05 22.9 0.2 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 OAG35900.1 - 0.00012 22.3 0.1 0.00021 21.5 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 OAG35900.1 - 0.00017 21.9 0.1 0.00023 21.5 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 OAG35900.1 - 0.0038 17.3 0.0 0.0045 17.0 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 OAG35900.1 - 0.0045 17.0 0.0 0.0054 16.7 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated UPF0137 PF03677.13 OAG35900.1 - 0.05 13.4 0.2 0.061 13.1 0.2 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) TFIID_20kDa PF03847.13 OAG35900.1 - 0.059 13.9 0.0 0.12 12.9 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A HIGH_NTase1_ass PF16581.5 OAG35900.1 - 0.073 13.1 0.0 0.082 12.9 0.0 1.1 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region Lectin_leg-like PF03388.13 OAG35901.1 - 4.6e-62 209.4 0.0 5.6e-62 209.1 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.19 OAG35901.1 - 3.4e-05 23.5 0.0 0.01 15.4 0.0 2.1 2 0 0 2 2 2 2 Legume lectin domain zf-Tim10_DDP PF02953.15 OAG35902.1 - 1.1e-20 73.0 0.9 1.9e-20 72.3 0.9 1.4 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Sporozoite_P67 PF05642.11 OAG35902.1 - 1.9 6.5 9.9 2.2 6.3 9.9 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Macoilin PF09726.9 OAG35902.1 - 3.8 6.0 5.5 4.2 5.8 5.5 1.0 1 0 0 1 1 1 0 Macoilin family Pkinase PF00069.25 OAG35903.1 - 4.7e-71 239.3 0.0 5.8e-71 239.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG35903.1 - 8.9e-38 130.0 0.0 1.3e-37 129.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAG35903.1 - 1.1e-05 25.0 0.0 1.6e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like CRIM PF16978.5 OAG35904.1 - 9.8e-43 145.7 0.0 1.7e-42 144.9 0.0 1.4 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), middle CRIM domain SIN1_PH PF16979.5 OAG35904.1 - 9.7e-20 70.9 0.1 1.6e-19 70.2 0.1 1.4 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology UCH PF00443.29 OAG35905.1 - 2.4e-35 122.3 0.0 3.8e-35 121.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP_var PF17807.1 OAG35905.1 - 9.5e-26 89.3 2.3 2.2e-24 85.0 0.2 2.6 2 0 0 2 2 2 1 Variant UBP zinc finger zf-UBP PF02148.19 OAG35905.1 - 5.8e-25 87.4 9.4 5.4e-19 68.3 1.0 3.0 2 0 0 2 2 2 2 Zn-finger in ubiquitin-hydrolases and other protein UBA PF00627.31 OAG35905.1 - 9.1e-19 67.0 0.3 3.5e-11 42.8 0.1 2.5 2 0 0 2 2 2 2 UBA/TS-N domain UCH_1 PF13423.6 OAG35905.1 - 3.7e-16 59.6 1.3 2.8e-08 33.7 0.0 3.3 3 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase UBA_4 PF14555.6 OAG35905.1 - 0.0039 17.0 0.0 0.0079 16.0 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain DUF2180 PF09947.9 OAG35905.1 - 0.41 10.7 8.6 20 5.2 0.4 3.9 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2180) BOP1NT PF08145.12 OAG35906.1 - 1.5e-105 352.8 7.8 2.1e-105 352.3 7.8 1.2 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 OAG35906.1 - 5.7e-20 71.3 9.1 1.2e-07 32.3 0.1 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG35906.1 - 0.00039 20.6 0.0 0.84 10.0 0.0 3.1 2 2 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain 4HBT PF03061.22 OAG35907.1 - 1.4e-14 54.2 0.1 2.3e-14 53.5 0.1 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_2 PF13279.6 OAG35907.1 - 0.015 15.7 0.0 0.028 14.9 0.0 1.4 1 1 0 1 1 1 0 Thioesterase-like superfamily DUF4442 PF14539.6 OAG35907.1 - 0.069 13.3 0.0 0.081 13.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) PXA PF02194.15 OAG35909.1 - 3.9e-37 128.0 0.3 7.8e-37 127.0 0.3 1.5 1 0 0 1 1 1 1 PXA domain Nexin_C PF08628.12 OAG35909.1 - 2.1e-20 73.4 0.0 6.1e-20 71.9 0.0 1.9 1 0 0 1 1 1 1 Sorting nexin C terminal PX PF00787.24 OAG35909.1 - 1e-06 28.7 0.0 4e-06 26.8 0.0 2.1 1 0 0 1 1 1 1 PX domain His_biosynth PF00977.21 OAG35910.1 - 5.8e-45 153.5 0.2 2.7e-44 151.3 0.2 2.1 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.28 OAG35910.1 - 1.4e-21 77.2 0.0 2.1e-21 76.5 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.19 OAG35910.1 - 5e-10 39.5 0.0 3e-07 30.5 0.0 2.2 2 0 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.14 OAG35910.1 - 2e-07 30.8 0.0 6.5e-07 29.1 0.0 1.8 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.13 OAG35910.1 - 0.014 15.2 0.0 0.091 12.5 0.0 2.2 1 1 0 1 1 1 0 Peptidase C26 Acyltransferase PF01553.21 OAG35911.1 - 3.9e-32 110.7 0.0 6.1e-32 110.1 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Rad52_Rad22 PF04098.15 OAG35912.1 - 6.2e-59 198.3 0.1 8.5e-59 197.9 0.1 1.2 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein DUF3433 PF11915.8 OAG35913.1 - 7.2e-39 132.2 13.2 1.2e-21 76.9 2.7 3.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3433) p450 PF00067.22 OAG35914.1 - 1.1e-55 189.3 0.0 1.6e-55 188.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Amino_oxidase PF01593.24 OAG35914.1 - 3e-48 165.2 0.0 1.1e-47 163.4 0.0 1.9 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OAG35914.1 - 4.4e-06 26.8 0.0 1.2e-05 25.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAG35914.1 - 0.021 14.0 0.0 0.037 13.3 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAG35914.1 - 0.04 13.0 0.4 0.075 12.1 0.4 1.4 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.24 OAG35914.1 - 0.059 12.9 0.2 0.12 11.9 0.2 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 OAG35914.1 - 0.09 11.5 0.2 0.14 10.8 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein DUF676 PF05057.14 OAG35915.1 - 0.00012 21.7 0.2 0.00019 21.0 0.2 1.5 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 OAG35915.1 - 0.00064 20.4 0.0 0.00075 20.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 OAG35915.1 - 0.026 14.2 0.0 0.036 13.8 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Hydrolase_4 PF12146.8 OAG35915.1 - 0.13 11.6 0.1 0.51 9.6 0.0 1.9 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_8 PF06259.12 OAG35915.1 - 0.14 11.8 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase LCAT PF02450.15 OAG35915.1 - 0.2 10.8 0.0 0.32 10.1 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF2208 PF09973.9 OAG35915.1 - 0.24 11.0 0.0 0.36 10.4 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2208) Iwr1 PF08574.10 OAG35916.1 - 2.3e-15 57.4 18.1 2.3e-15 57.4 18.1 2.0 2 0 0 2 2 2 1 Transcription factor Iwr1 PUF PF00806.19 OAG35918.1 - 4.5e-31 104.8 0.0 2.3e-05 23.8 0.0 6.7 6 0 0 6 6 6 6 Pumilio-family RNA binding repeat RRM_1 PF00076.22 OAG35918.1 - 1.5e-12 47.1 0.0 6.8e-12 45.0 0.0 2.1 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OAG35918.1 - 0.041 13.8 0.0 0.092 12.6 0.0 1.6 1 0 0 1 1 1 0 Occluded RNA-recognition motif SET_assoc PF11767.8 OAG35918.1 - 0.12 12.0 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated Myb_DNA-binding PF00249.31 OAG35919.1 - 3.5e-12 46.3 0.1 2.8e-05 24.2 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OAG35919.1 - 4e-10 39.8 0.1 0.00062 20.0 0.0 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 OAG35919.1 - 8e-05 22.8 1.7 0.021 15.0 0.2 2.3 2 0 0 2 2 2 2 SANT/Myb-like domain of DAMP1 SLIDE PF09111.10 OAG35919.1 - 0.00053 20.0 0.0 0.32 11.0 0.1 2.5 2 0 0 2 2 2 2 SLIDE CHDCT2 PF08074.11 OAG35919.1 - 0.018 15.2 1.5 1.5 8.9 0.1 2.6 3 0 0 3 3 3 0 CHDCT2 (NUC038) domain PX PF00787.24 OAG35920.1 - 3.3e-25 88.3 0.1 4.8e-25 87.7 0.1 1.3 1 0 0 1 1 1 1 PX domain DNA_pol_phi PF04931.13 OAG35921.1 - 5.6e-159 530.7 45.1 1.4e-158 529.4 43.6 2.2 2 1 0 2 2 2 1 DNA polymerase phi DUF2951 PF11166.8 OAG35921.1 - 0.057 13.6 1.3 0.3 11.3 1.3 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) RIH_assoc PF08454.11 OAG35921.1 - 0.095 12.6 1.0 5 7.0 0.0 3.6 4 0 0 4 4 4 0 RyR and IP3R Homology associated BUD22 PF09073.10 OAG35921.1 - 0.29 10.4 27.0 0.57 9.5 27.0 1.4 1 0 0 1 1 1 0 BUD22 ArAE_2_N PF10337.9 OAG35923.1 - 9.4e-30 104.1 12.1 5.2e-29 101.6 5.0 3.4 2 2 0 2 2 2 2 Putative ER transporter, 6TM, N-terminal FUSC_2 PF13515.6 OAG35923.1 - 8.9e-16 58.2 11.5 8.9e-16 58.2 11.5 3.2 3 0 0 3 3 3 1 Fusaric acid resistance protein-like ArAE_2 PF10334.9 OAG35923.1 - 1.4e-09 38.1 0.0 1.1e-06 28.7 0.0 3.1 3 0 0 3 3 3 2 Aromatic acid exporter family member 2 His_Phos_1 PF00300.22 OAG35924.1 - 7.8e-36 123.6 0.1 1.3e-18 67.5 0.1 2.4 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) ArfGap PF01412.18 OAG35926.1 - 2.1e-11 43.9 0.1 4.7e-11 42.8 0.1 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf DUF4337 PF14235.6 OAG35926.1 - 0.066 13.3 1.4 0.14 12.2 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) CHCH PF06747.13 OAG35929.1 - 3e-06 27.2 5.7 4.8e-06 26.6 5.7 1.3 1 0 0 1 1 1 1 CHCH domain PP2C_C PF07830.13 OAG35929.1 - 0.46 11.0 2.1 0.63 10.5 0.3 2.1 2 0 0 2 2 2 0 Protein serine/threonine phosphatase 2C, C-terminal domain SgrT PF15894.5 OAG35930.1 - 0.038 14.0 0.0 0.11 12.5 0.0 1.8 1 0 0 1 1 1 0 Inhibitor of glucose uptake transporter SgrT TPK_catalytic PF04263.16 OAG35931.1 - 4.7e-30 104.1 0.0 6.5e-30 103.7 0.0 1.2 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 OAG35931.1 - 5.9e-16 57.9 0.0 9.5e-16 57.3 0.0 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain MIF4G PF02854.19 OAG35932.1 - 5.3e-63 212.5 0.4 1.2e-33 116.5 0.2 3.5 3 0 0 3 3 3 3 MIF4G domain Upf2 PF04050.14 OAG35932.1 - 1.9e-18 67.5 23.7 1.4e-11 45.3 0.7 3.9 3 1 1 4 4 4 2 Up-frameshift suppressor 2 Fib_alpha PF08702.10 OAG35932.1 - 0.52 10.5 3.7 0.5 10.5 1.2 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Ribosomal_L1 PF00687.21 OAG35933.1 - 2.9e-57 193.7 1.3 4.2e-57 193.2 1.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family ETF PF01012.21 OAG35934.1 - 4.2e-43 147.3 0.8 7.3e-43 146.6 0.8 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 OAG35934.1 - 2.6e-33 113.9 0.1 5.4e-33 112.9 0.1 1.6 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain MRC1 PF09444.10 OAG35934.1 - 0.3 11.6 1.6 0.46 11.0 0.3 1.9 2 0 0 2 2 2 0 MRC1-like domain Zn_clus PF00172.18 OAG35935.1 - 2.9e-07 30.5 8.1 2.9e-07 30.5 8.1 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAG35935.1 - 9.6e-06 24.8 0.3 2.6e-05 23.4 0.2 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF2039 PF10217.9 OAG35935.1 - 0.48 10.8 7.7 0.22 11.9 4.8 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) HLH PF00010.26 OAG35936.1 - 3e-09 36.7 0.0 1.6e-08 34.3 0.0 2.2 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain HLH PF00010.26 OAG35937.1 - 7.8e-08 32.2 0.2 2.1e-07 30.8 0.2 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain TGase_elicitor PF16683.5 OAG35937.1 - 0.016 14.0 0.3 0.036 12.8 0.3 1.5 1 0 0 1 1 1 0 Transglutaminase elicitor DUF5082 PF16888.5 OAG35937.1 - 0.43 10.9 9.1 0.065 13.5 3.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) Fungal_trans PF04082.18 OAG35938.1 - 5e-10 38.8 5.0 8.1e-10 38.2 5.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG35938.1 - 5.5e-06 26.4 9.5 1.1e-05 25.4 9.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2039 PF10217.9 OAG35938.1 - 0.066 13.6 6.1 0.21 11.9 6.1 1.8 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) Peptidase_S8 PF00082.22 OAG35939.1 - 5.8e-19 68.5 0.0 1.3e-18 67.4 0.0 1.5 1 0 0 1 1 1 1 Subtilase family Ank_5 PF13857.6 OAG35939.1 - 4.1e-07 30.2 0.0 0.058 13.7 0.0 3.4 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 OAG35939.1 - 9.5e-07 29.0 0.0 0.0019 18.6 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 OAG35939.1 - 1.1e-06 29.1 0.1 0.0034 17.9 0.0 2.8 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OAG35939.1 - 1.2e-05 25.3 0.1 0.3 11.8 0.0 3.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 OAG35939.1 - 0.0021 18.6 1.4 1.6 9.4 0.0 3.7 3 1 1 4 4 4 1 Ankyrin repeats (many copies) MFS_1 PF07690.16 OAG35941.1 - 1.7e-29 102.9 56.1 8e-19 67.8 27.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MRP-S27 PF10037.9 OAG35942.1 - 0.052 12.4 1.5 0.073 11.9 1.5 1.2 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 RXT2_N PF08595.11 OAG35943.1 - 0.025 14.6 4.6 0.028 14.5 4.6 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal FYDLN_acid PF09538.10 OAG35943.1 - 0.045 14.4 9.6 0.058 14.1 9.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) MPP6 PF10175.9 OAG35943.1 - 0.047 14.2 2.6 0.066 13.7 2.6 1.2 1 0 0 1 1 1 0 M-phase phosphoprotein 6 MRNIP PF15749.5 OAG35943.1 - 0.098 13.4 0.2 0.12 13.1 0.2 1.2 1 0 0 1 1 1 0 MRN-interacting protein Nop14 PF04147.12 OAG35943.1 - 0.11 10.7 12.7 0.11 10.7 12.7 1.0 1 0 0 1 1 1 0 Nop14-like family FAM176 PF14851.6 OAG35943.1 - 0.59 9.8 6.4 0.8 9.4 6.4 1.3 1 0 0 1 1 1 0 FAM176 family BUD22 PF09073.10 OAG35943.1 - 1 8.6 11.1 1.2 8.5 11.1 1.0 1 0 0 1 1 1 0 BUD22 Sigma70_ner PF04546.13 OAG35943.1 - 1.1 9.1 10.4 1.3 8.9 10.4 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region TFB6 PF17110.5 OAG35943.1 - 1.4 8.6 5.0 1.8 8.3 5.0 1.2 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH DNA_pol_phi PF04931.13 OAG35943.1 - 2.3 6.2 20.5 2.7 6.0 20.5 1.0 1 0 0 1 1 1 0 DNA polymerase phi RNA_pol_3_Rpc31 PF11705.8 OAG35943.1 - 2.4 8.4 22.3 3.3 7.9 22.3 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Astro_capsid_p PF12226.8 OAG35943.1 - 3.1 6.9 12.6 3.2 6.8 12.6 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Paf1 PF03985.13 OAG35943.1 - 3.2 6.6 11.9 3.9 6.4 11.9 1.0 1 0 0 1 1 1 0 Paf1 LAT PF15234.6 OAG35943.1 - 3.4 7.3 7.8 3.5 7.3 7.8 1.2 1 0 0 1 1 1 0 Linker for activation of T-cells Pox_Ag35 PF03286.14 OAG35943.1 - 3.7 7.3 7.8 4.4 7.1 7.8 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF2457 PF10446.9 OAG35943.1 - 3.8 6.6 22.7 4.5 6.3 22.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Ribosomal_60s PF00428.19 OAG35943.1 - 3.8 8.2 16.3 0.068 13.8 8.7 1.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein CDC45 PF02724.14 OAG35943.1 - 5.3 5.2 11.8 5.7 5.1 11.8 1.0 1 0 0 1 1 1 0 CDC45-like protein HSP90 PF00183.18 OAG35943.1 - 6.8 5.5 7.3 7.7 5.3 7.3 1.0 1 0 0 1 1 1 0 Hsp90 protein SDA1 PF05285.12 OAG35943.1 - 7 6.0 14.8 8.4 5.7 14.8 1.0 1 0 0 1 1 1 0 SDA1 Sporozoite_P67 PF05642.11 OAG35943.1 - 9.3 4.2 8.4 9.2 4.2 8.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen adh_short PF00106.25 OAG35944.1 - 3e-28 98.6 0.0 4.2e-28 98.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG35944.1 - 3.8e-24 85.5 0.0 5.2e-24 85.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG35944.1 - 1.3e-07 31.7 0.0 2e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 OAG35944.1 - 0.0028 17.9 0.1 0.0052 17.0 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 OAG35944.1 - 0.02 14.3 0.0 1.6 8.1 0.0 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 OAG35944.1 - 0.065 13.3 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Glyco_hydro_72 PF03198.14 OAG35946.1 - 2.1e-137 457.6 1.3 2.5e-137 457.3 1.3 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 OAG35946.1 - 1.1e-05 25.1 0.2 3.6e-05 23.4 0.2 1.8 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.17 OAG35946.1 - 0.0048 16.1 0.0 0.023 13.8 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain DNA_binding_1 PF01035.20 OAG35947.1 - 1.3e-26 92.5 0.0 2.4e-26 91.7 0.0 1.4 2 0 0 2 2 2 1 6-O-methylguanine DNA methyltransferase, DNA binding domain GCS PF03074.16 OAG35948.1 - 6.3e-172 572.0 0.0 7.7e-172 571.7 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase Transp_cyt_pur PF02133.15 OAG35949.1 - 1.1e-145 485.8 43.9 1.3e-145 485.5 43.9 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF1771 PF08590.10 OAG35950.1 - 6.2e-23 80.9 10.9 6.2e-23 80.9 10.9 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.21 OAG35950.1 - 5e-11 42.8 0.4 1.9e-10 41.0 0.4 2.0 1 0 0 1 1 1 1 Smr domain Fungal_trans PF04082.18 OAG35950.1 - 2.1e-10 40.1 0.1 4.7e-10 38.9 0.1 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain HSCB_C PF07743.13 OAG35950.1 - 0.23 12.0 3.1 8.5 6.9 0.0 2.9 2 0 0 2 2 2 0 HSCB C-terminal oligomerisation domain G-alpha PF00503.20 OAG35951.1 - 9.1e-124 413.2 0.8 1.1e-123 413.0 0.8 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 OAG35951.1 - 1.1e-15 57.5 1.1 1.5e-10 40.8 0.1 2.6 2 0 0 2 2 2 2 ADP-ribosylation factor family zf-CHC2 PF01807.20 OAG35951.1 - 0.00034 20.4 0.0 0.0015 18.3 0.0 1.9 2 0 0 2 2 2 1 CHC2 zinc finger Gtr1_RagA PF04670.12 OAG35951.1 - 0.0033 16.8 5.0 0.034 13.5 0.3 2.4 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 OAG35951.1 - 0.011 15.9 1.1 2.4 8.4 0.0 2.9 2 1 1 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 OAG35951.1 - 0.024 14.4 0.0 0.053 13.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain MCM PF00493.23 OAG35951.1 - 0.054 12.6 0.0 0.097 11.7 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain FtsK_SpoIIIE PF01580.18 OAG35951.1 - 0.082 12.2 0.0 0.18 11.1 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.23 OAG35951.1 - 0.085 12.9 0.1 5.8 7.0 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OAG35951.1 - 0.12 11.9 0.0 1.3 8.5 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain MFS_1 PF07690.16 OAG35952.1 - 1.3e-31 109.9 23.6 1.3e-31 109.9 23.6 1.8 1 1 0 2 2 2 1 Major Facilitator Superfamily DIOX_N PF14226.6 OAG35953.1 - 9e-16 58.7 0.0 1.5e-15 58.0 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OAG35953.1 - 6.9e-11 42.5 0.0 1.1e-10 41.9 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily IDO PF01231.18 OAG35954.1 - 9.5e-149 495.9 0.0 3.2e-146 487.5 0.0 2.0 1 1 0 1 1 1 1 Indoleamine 2,3-dioxygenase Pol_alpha_B_N PF08418.10 OAG35955.1 - 0.001 19.1 9.2 0.001 19.1 9.2 3.7 3 1 0 3 3 3 1 DNA polymerase alpha subunit B N-terminal Macoilin PF09726.9 OAG35955.1 - 8.1 4.9 8.9 17 3.8 8.9 1.4 1 0 0 1 1 1 0 Macoilin family UEV PF05743.13 OAG35956.1 - 5.4e-39 132.8 0.0 1e-38 131.9 0.0 1.5 1 0 0 1 1 1 1 UEV domain HET PF06985.11 OAG35956.1 - 3.1e-22 79.5 1.9 9.4e-22 77.9 0.1 2.3 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Vps23_core PF09454.10 OAG35956.1 - 1e-15 57.4 0.0 2.9e-15 56.0 0.0 1.8 1 0 0 1 1 1 1 Vps23 core domain UQ_con PF00179.26 OAG35956.1 - 0.022 14.4 0.1 0.061 13.0 0.1 1.7 1 0 0 1 1 1 0 Ubiquitin-conjugating enzyme CALCOCO1 PF07888.11 OAG35956.1 - 0.038 12.9 0.5 0.066 12.1 0.5 1.3 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like HAUS-augmin3 PF14932.6 OAG35956.1 - 0.079 12.5 3.1 0.17 11.5 3.1 1.5 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF724 PF05266.14 OAG35956.1 - 0.16 11.8 0.4 0.36 10.6 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Baculo_PEP_C PF04513.12 OAG35956.1 - 0.86 9.6 6.7 3.7 7.6 6.5 1.8 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus THOC7 PF05615.13 OAG35956.1 - 1.2 9.5 2.8 11 6.3 0.6 2.8 2 0 0 2 2 2 0 Tho complex subunit 7 BST2 PF16716.5 OAG35956.1 - 3.5 8.3 8.1 0.64 10.6 3.9 2.0 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 CsbD PF05532.12 OAG35957.1 - 7e-12 45.1 18.5 3.6e-10 39.6 7.0 3.3 2 1 1 3 3 3 3 CsbD-like Use1 PF09753.9 OAG35958.1 - 4.8e-07 29.8 2.7 8.3e-07 29.0 2.7 1.5 1 1 0 1 1 1 1 Membrane fusion protein Use1 DUF2105 PF09878.9 OAG35958.1 - 0.11 12.2 0.3 0.17 11.6 0.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2105) TolA_bind_tri PF16331.5 OAG35958.1 - 0.15 12.1 3.6 0.77 9.9 0.2 2.7 2 0 0 2 2 2 0 TolA binding protein trimerisation Zn_clus PF00172.18 OAG35959.1 - 2.6e-10 40.3 12.9 4.1e-10 39.6 12.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AAA_11 PF13086.6 OAG35960.1 - 1.3e-09 38.2 0.0 0.00014 21.7 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_12 PF13087.6 OAG35960.1 - 3.2e-05 23.6 0.0 5.8e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 OAG35960.1 - 0.00013 21.8 0.0 0.00033 20.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain Patatin PF01734.22 OAG35961.1 - 4.2e-18 66.3 0.0 8e-18 65.4 0.0 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase ERCC4 PF02732.15 OAG35962.1 - 1.6e-17 64.2 0.0 3.1e-17 63.2 0.0 1.5 1 0 0 1 1 1 1 ERCC4 domain HHH_5 PF14520.6 OAG35962.1 - 0.064 13.9 0.0 0.24 12.0 0.0 2.0 2 0 0 2 2 2 0 Helix-hairpin-helix domain eIF-1a PF01176.19 OAG35963.1 - 8.1e-22 76.8 0.0 1.1e-21 76.3 0.0 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Ribonuclease_P PF00825.18 OAG35964.1 - 0.0027 17.8 0.4 0.0038 17.3 0.4 1.3 1 0 0 1 1 1 1 Ribonuclease P fn3_2 PF16893.5 OAG35965.1 - 1.9e-36 124.1 0.2 3.2e-36 123.3 0.2 1.4 1 0 0 1 1 1 1 Fibronectin type III domain CHS5_N PF16892.5 OAG35965.1 - 6.1e-24 83.7 0.4 4.2e-23 81.0 0.5 2.1 2 0 0 2 2 2 1 Chitin biosynthesis protein CHS5 N-terminus PTCB-BRCT PF12738.7 OAG35965.1 - 1.8e-14 53.4 0.0 4.5e-14 52.2 0.0 1.6 2 0 0 2 2 2 1 twin BRCT domain BRCT PF00533.26 OAG35965.1 - 4.3e-09 36.6 0.0 7.4e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DUF3006 PF11213.8 OAG35965.1 - 8.3e-05 22.7 0.0 0.00024 21.2 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3006) BRCT_2 PF16589.5 OAG35965.1 - 0.0016 18.8 0.0 0.0036 17.7 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain fn3 PF00041.21 OAG35965.1 - 0.062 13.6 0.0 0.31 11.4 0.0 2.2 1 1 0 1 1 1 0 Fibronectin type III domain SDA1 PF05285.12 OAG35965.1 - 3.8 6.8 12.5 5.5 6.3 12.5 1.2 1 0 0 1 1 1 0 SDA1 But2 PF09792.9 OAG35966.1 - 8.6e-06 26.2 0.0 1.9e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain TGF_beta_GS PF08515.12 OAG35966.1 - 2.3 7.8 6.6 2.1 7.9 1.0 2.6 2 0 0 2 2 2 0 Transforming growth factor beta type I GS-motif CorA PF01544.18 OAG35967.1 - 1.9e-40 139.0 0.3 8.2e-39 133.7 0.3 2.2 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein XhlA PF10779.9 OAG35967.1 - 0.81 9.9 2.4 2.1 8.6 2.4 1.7 1 0 0 1 1 1 0 Haemolysin XhlA Bacillus_HBL PF05791.11 OAG35968.1 - 0.018 14.8 0.8 0.045 13.6 0.8 1.6 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) Tup_N PF08581.10 OAG35968.1 - 0.45 10.8 9.1 0.27 11.6 4.5 2.9 1 1 1 2 2 2 0 Tup N-terminal PT PF04886.12 OAG35968.1 - 1.8 8.2 26.1 0.23 11.1 4.8 5.2 3 1 1 4 4 4 0 PT repeat Epimerase PF01370.21 OAG35969.1 - 7.9e-19 68.1 0.0 1.1e-18 67.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAG35969.1 - 6.9e-11 42.1 0.0 9.2e-11 41.7 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 OAG35969.1 - 7.4e-07 28.6 0.0 9.7e-07 28.2 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.19 OAG35969.1 - 4e-06 26.1 0.0 6.4e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 OAG35969.1 - 0.00012 21.4 0.1 0.00023 20.4 0.0 1.4 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 OAG35969.1 - 0.0077 15.4 0.0 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain DUF1501 PF07394.12 OAG35970.1 - 0.49 9.4 5.0 0.99 8.4 4.6 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1501) FUSC_2 PF13515.6 OAG35971.1 - 6.2e-31 107.2 1.8 6.2e-31 107.2 1.8 3.3 2 1 1 3 3 3 1 Fusaric acid resistance protein-like ALMT PF11744.8 OAG35971.1 - 2.7e-05 23.2 16.3 0.00047 19.1 0.5 3.8 4 0 0 4 4 4 3 Aluminium activated malate transporter ArAE_2 PF10334.9 OAG35971.1 - 0.00012 21.9 0.3 0.0015 18.4 0.1 2.2 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 FUSC PF04632.12 OAG35971.1 - 0.0038 15.8 16.5 0.14 10.7 3.0 3.5 3 1 0 3 3 3 2 Fusaric acid resistance protein family FUSC-like PF12805.7 OAG35971.1 - 0.004 16.3 2.3 0.057 12.5 0.1 2.8 2 1 0 2 2 2 1 FUSC-like inner membrane protein yccS Glycoprotein_G PF00802.19 OAG35971.1 - 0.14 11.5 0.1 0.23 10.8 0.1 1.3 1 0 0 1 1 1 0 Pneumovirus attachment glycoprotein G 2OG-FeII_Oxy_2 PF13532.6 OAG35972.1 - 2.8e-35 122.3 0.0 2.2e-34 119.4 0.0 2.0 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily HalX PF08663.10 OAG35972.1 - 0.11 12.8 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 HalX domain Amidase PF01425.21 OAG35973.1 - 4.2e-106 355.6 0.0 5.1e-106 355.3 0.0 1.1 1 0 0 1 1 1 1 Amidase zf-Di19 PF05605.12 OAG35974.1 - 0.021 15.1 0.2 0.039 14.2 0.2 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Synaptobrevin PF00957.21 OAG35974.1 - 0.021 14.6 1.0 0.052 13.3 1.0 1.6 1 0 0 1 1 1 0 Synaptobrevin zf-C2H2_4 PF13894.6 OAG35974.1 - 0.03 15.1 0.7 0.1 13.5 0.7 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2HC_2 PF13913.6 OAG35974.1 - 0.043 13.7 0.2 0.082 12.8 0.2 1.4 1 0 0 1 1 1 0 zinc-finger of a C2HC-type Exonuc_VII_L PF02601.15 OAG35974.1 - 0.37 10.3 2.0 0.61 9.6 2.0 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DivIC PF04977.15 OAG35974.1 - 0.65 9.8 7.0 1.3 8.8 7.0 1.4 1 0 0 1 1 1 0 Septum formation initiator DUF5595 PF18077.1 OAG35974.1 - 0.68 10.1 3.6 1.4 9.0 3.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5595) DUF2946 PF11162.8 OAG35974.1 - 0.77 10.4 5.9 0.47 11.1 0.3 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2946) DUF3958 PF13125.6 OAG35974.1 - 1.5 9.1 11.8 13 6.1 11.8 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3958) bZIP_2 PF07716.15 OAG35974.1 - 2.6 8.2 9.8 8.7 6.5 9.8 1.9 1 0 0 1 1 1 0 Basic region leucine zipper Mg_trans_NIPA PF05653.14 OAG35975.1 - 8.2e-86 287.8 29.9 1.3e-84 283.8 29.9 2.0 1 1 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 OAG35975.1 - 6.4e-05 23.1 5.6 6.4e-05 23.1 5.6 4.1 3 1 0 3 3 3 1 EamA-like transporter family AA_permease_2 PF13520.6 OAG35976.1 - 3.6e-49 167.7 50.4 4.5e-49 167.4 50.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAG35976.1 - 3.5e-13 49.0 34.7 3.5e-13 49.0 34.7 1.3 2 0 0 2 2 2 1 Amino acid permease Fungal_trans_2 PF11951.8 OAG35977.1 - 1.6e-05 23.9 0.6 2.2e-05 23.5 0.6 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain FMO-like PF00743.19 OAG35978.1 - 6.8e-22 77.6 0.0 1.7e-17 63.1 0.0 2.8 2 1 1 3 3 3 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 OAG35978.1 - 7.7e-15 54.9 0.0 2.8e-13 49.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG35978.1 - 8.9e-13 48.2 0.3 7.5e-09 35.3 0.0 3.5 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG35978.1 - 4e-09 36.1 0.0 0.00012 21.3 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 OAG35978.1 - 2.9e-07 30.4 0.5 2.5e-05 24.1 0.0 2.5 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAG35978.1 - 6.2e-06 26.3 0.1 7.4e-05 22.9 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 OAG35978.1 - 9.4e-06 26.1 0.2 0.051 14.1 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAG35978.1 - 0.0007 18.8 0.0 0.0011 18.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Shikimate_DH PF01488.20 OAG35978.1 - 0.0016 18.5 0.1 0.14 12.2 0.0 2.6 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.6 OAG35978.1 - 0.026 14.5 0.5 0.41 10.6 0.1 3.1 5 0 0 5 5 5 0 FAD-NAD(P)-binding Thi4 PF01946.17 OAG35978.1 - 0.035 13.3 0.0 0.074 12.3 0.0 1.4 1 0 0 1 1 1 0 Thi4 family NAD_binding_7 PF13241.6 OAG35978.1 - 0.039 14.4 0.0 36 4.9 0.0 3.3 3 0 0 3 3 3 0 Putative NAD(P)-binding HI0933_like PF03486.14 OAG35978.1 - 0.075 11.7 1.6 0.15 10.7 1.6 1.5 1 0 0 1 1 1 0 HI0933-like protein FAD_oxidored PF12831.7 OAG35978.1 - 0.091 12.1 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.19 OAG35978.1 - 0.12 11.7 0.0 0.43 9.9 0.0 1.9 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Fungal_trans PF04082.18 OAG35979.1 - 4.3e-18 65.3 0.0 8.5e-18 64.3 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain p450 PF00067.22 OAG35980.1 - 5.3e-57 193.6 0.0 3e-44 151.5 0.0 2.1 1 1 1 2 2 2 2 Cytochrome P450 Sugar_tr PF00083.24 OAG35981.1 - 1.4e-114 383.4 23.4 1.7e-114 383.2 23.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG35981.1 - 1.8e-18 66.6 41.8 6.2e-18 64.8 35.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily FAD_binding_4 PF01565.23 OAG35982.1 - 4.9e-27 94.4 0.0 9.4e-27 93.5 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.19 OAG35982.1 - 8.7e-07 28.8 0.0 1.3e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain Fungal_trans PF04082.18 OAG35983.1 - 6.4e-22 77.9 0.0 1e-21 77.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sugar_tr PF00083.24 OAG35984.1 - 1.2e-85 288.1 22.5 1.4e-85 287.9 22.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG35984.1 - 6.4e-25 87.8 33.5 7.4e-18 64.6 13.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily p450 PF00067.22 OAG35985.1 - 2.4e-51 175.0 0.0 7.9e-51 173.2 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 Sugar_tr PF00083.24 OAG35986.1 - 1.4e-76 258.2 31.7 1.6e-76 258.0 31.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG35986.1 - 4.7e-31 108.0 29.0 4.7e-31 108.0 29.0 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1440 PF07274.12 OAG35986.1 - 2.7 8.3 7.4 6.2 7.2 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1440) Fungal_trans PF04082.18 OAG35987.1 - 2.2e-25 89.2 1.8 3.3e-25 88.6 1.8 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sugar_tr PF00083.24 OAG35988.1 - 1.2e-83 281.5 22.6 1.4e-83 281.3 22.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG35988.1 - 1.5e-35 122.8 32.7 1.5e-35 122.8 32.7 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily p450 PF00067.22 OAG35989.1 - 1.4e-56 192.2 0.0 1.7e-56 191.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PBP_sp32 PF07222.12 OAG35989.1 - 0.044 13.2 0.0 0.076 12.5 0.0 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Aldo_ket_red PF00248.21 OAG35990.1 - 1.2e-62 211.8 0.0 2e-62 211.0 0.0 1.3 1 0 0 1 1 1 1 Aldo/keto reductase family FAD_binding_1 PF00667.20 OAG35990.1 - 2.3e-60 203.9 0.0 4e-60 203.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 OAG35990.1 - 5.2e-36 124.0 0.3 1.3e-35 122.7 0.3 1.7 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 OAG35990.1 - 1.3e-18 67.7 0.1 1.1e-17 64.7 0.0 2.7 3 0 0 3 3 3 1 Oxidoreductase NAD-binding domain SnoaL_3 PF13474.6 OAG35990.1 - 1.2e-09 38.5 0.1 7.6e-09 35.9 0.0 2.2 2 0 0 2 2 2 1 SnoaL-like domain DUF4440 PF14534.6 OAG35990.1 - 0.00012 22.5 0.1 0.00032 21.0 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) MmgE_PrpD PF03972.14 OAG35991.1 - 3.5e-103 345.5 3.4 4.2e-103 345.2 3.4 1.0 1 0 0 1 1 1 1 MmgE/PrpD family Methyltransf_2 PF00891.18 OAG35992.1 - 1.2e-26 93.3 0.0 1.9e-26 92.7 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_34 PF11312.8 OAG35992.1 - 0.021 14.1 0.0 0.034 13.4 0.0 1.2 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase CYTH PF01928.21 OAG35993.1 - 0.00028 20.9 0.3 0.0013 18.7 0.1 2.0 2 0 0 2 2 2 1 CYTH domain COXG PF06240.13 OAG35993.1 - 0.061 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Carbon monoxide dehydrogenase subunit G (CoxG) AA_permease PF00324.21 OAG35995.1 - 1.2e-124 416.5 40.4 4.7e-122 408.0 40.4 2.0 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAG35995.1 - 6.3e-33 114.2 35.2 2.1e-28 99.3 17.1 2.0 1 1 1 2 2 2 2 Amino acid permease ADH_zinc_N PF00107.26 OAG35996.1 - 2.4e-19 69.6 0.0 3.5e-19 69.1 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 OAG35996.1 - 1.6e-17 63.3 0.0 2.8e-17 62.6 0.0 1.3 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 OAG35996.1 - 3.7e-12 47.5 0.0 5.7e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF2855 PF11017.8 OAG35996.1 - 0.081 12.7 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2855) Orbi_VP5 PF00901.17 OAG35997.1 - 0.0073 14.7 0.0 0.011 14.2 0.0 1.2 1 0 0 1 1 1 1 Orbivirus outer capsid protein VP5 CMD PF02627.20 OAG35998.1 - 0.0057 16.7 0.3 0.01 15.8 0.2 1.5 1 1 0 1 1 1 1 Carboxymuconolactone decarboxylase family ABM PF03992.16 OAG35999.1 - 1e-05 25.6 0.5 0.015 15.4 0.1 2.4 2 0 0 2 2 2 2 Antibiotic biosynthesis monooxygenase Dabb PF07876.12 OAG35999.1 - 0.00053 20.6 0.0 0.0011 19.6 0.0 1.5 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain DUF1330 PF07045.11 OAG35999.1 - 0.0044 17.3 0.2 2.7 8.4 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF1330) FAD_binding_3 PF01494.19 OAG36000.1 - 2.6e-59 201.2 0.0 3.9e-59 200.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 OAG36000.1 - 0.0044 16.3 0.0 0.034 13.4 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAG36000.1 - 0.0067 17.0 0.0 0.059 13.9 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG36000.1 - 0.045 13.0 0.0 0.09 12.0 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG36000.1 - 0.084 13.1 0.1 0.21 11.8 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain ThiF PF00899.21 OAG36000.1 - 0.18 11.1 0.1 0.31 10.4 0.1 1.2 1 0 0 1 1 1 0 ThiF family adh_short PF00106.25 OAG36001.1 - 8.7e-31 106.9 0.0 1.1e-30 106.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG36001.1 - 4e-29 101.8 0.0 5.6e-29 101.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG36001.1 - 0.0013 18.7 0.8 0.0094 15.9 0.2 2.4 2 1 0 2 2 2 1 KR domain Epimerase PF01370.21 OAG36001.1 - 0.13 11.8 0.2 0.17 11.3 0.2 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Fungal_trans PF04082.18 OAG36002.1 - 1.1e-23 83.6 0.3 1.9e-23 82.8 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain LRRFIP PF09738.9 OAG36002.1 - 0.078 12.4 0.1 0.13 11.8 0.1 1.2 1 0 0 1 1 1 0 LRRFIP family TRI12 PF06609.13 OAG36003.1 - 8.3e-41 140.1 26.7 1.1e-40 139.7 26.7 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG36003.1 - 9.9e-23 80.6 50.1 9.9e-23 80.6 50.1 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG36003.1 - 6.8e-11 41.7 7.6 6.8e-11 41.7 7.6 3.8 2 1 2 4 4 4 1 Sugar (and other) transporter DUF3439 PF11921.8 OAG36003.1 - 3.8 7.5 5.6 1.5 8.8 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Glyoxalase PF00903.25 OAG36004.1 - 9e-14 51.8 0.2 1.2e-13 51.4 0.2 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily adh_short PF00106.25 OAG36005.1 - 8.9e-32 110.1 0.0 1.2e-31 109.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG36005.1 - 6.9e-27 94.5 0.0 8.5e-27 94.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG36005.1 - 1.2e-06 28.6 0.1 2e-06 27.8 0.1 1.4 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 OAG36005.1 - 0.0022 17.4 0.0 0.0038 16.7 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 OAG36005.1 - 0.012 15.1 0.1 0.016 14.7 0.1 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 OAG36005.1 - 0.05 12.7 0.1 0.08 12.1 0.1 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 OAG36005.1 - 0.053 13.4 0.4 0.13 12.1 0.2 1.8 2 1 0 2 2 2 0 NAD(P)H-binding DUF1776 PF08643.10 OAG36005.1 - 0.061 12.7 0.0 0.099 12.0 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) 3Beta_HSD PF01073.19 OAG36005.1 - 0.074 12.0 0.2 0.13 11.2 0.2 1.4 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Tagatose_6_P_K PF08013.11 OAG36005.1 - 0.079 11.6 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Tagatose 6 phosphate kinase adh_short PF00106.25 OAG36006.1 - 2e-33 115.5 0.1 2.6e-16 59.7 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAG36006.1 - 8.4e-28 97.5 0.1 5.3e-15 55.6 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG36006.1 - 4.4e-08 33.2 0.4 5.5e-06 26.4 0.1 2.2 2 0 0 2 2 2 2 KR domain FAD_binding_2 PF00890.24 OAG36007.1 - 1.3e-76 258.4 0.0 1.5e-76 258.2 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAG36007.1 - 3.3e-13 49.9 0.4 6.6e-08 32.5 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_oxidored PF12831.7 OAG36007.1 - 5.7e-11 42.4 1.6 2.5e-10 40.3 0.8 2.1 1 1 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 OAG36007.1 - 4.6e-08 32.6 0.1 4.4e-07 29.4 0.0 2.2 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 OAG36007.1 - 4.8e-08 32.1 0.3 9.4e-07 27.9 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.6 OAG36007.1 - 5.8e-07 29.7 0.2 1.4e-06 28.4 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAG36007.1 - 5.5e-06 25.8 0.1 2e-05 24.0 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG36007.1 - 0.006 15.9 0.1 0.013 14.7 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 OAG36007.1 - 0.013 14.7 0.1 0.062 12.5 0.2 2.0 3 0 0 3 3 3 0 FAD binding domain GDI PF00996.18 OAG36007.1 - 0.016 13.8 0.0 0.025 13.1 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor GIDA PF01134.22 OAG36007.1 - 0.027 13.6 2.8 0.036 13.1 0.6 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A p450 PF00067.22 OAG36008.1 - 9.3e-63 212.6 0.0 1.1e-62 212.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AMP-binding PF00501.28 OAG36009.1 - 2.3e-48 164.8 0.0 3.6e-48 164.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG36009.1 - 0.0008 20.3 0.1 0.0061 17.5 0.0 2.3 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain PsbR PF04725.12 OAG36009.1 - 0.011 16.1 1.3 0.018 15.3 0.2 2.0 2 0 0 2 2 2 0 Photosystem II 10 kDa polypeptide PsbR DUF1967 PF09269.11 OAG36009.1 - 0.12 12.3 0.4 2.4 8.2 0.1 3.0 4 0 0 4 4 4 0 Domain of unknown function (DUF1967) MFS_1 PF07690.16 OAG36010.1 - 8.5e-21 74.3 52.0 8.5e-21 74.3 52.0 3.1 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 OAG36010.1 - 1.9e-09 36.5 20.4 3.9e-09 35.5 17.8 2.0 1 1 1 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Pox_A14 PF05767.12 OAG36010.1 - 0.0031 17.6 0.6 0.013 15.6 0.6 2.1 1 0 0 1 1 1 1 Poxvirus virion envelope protein A14 K_oxygenase PF13434.6 OAG36011.1 - 2.8e-72 243.8 0.0 3.3e-72 243.5 0.0 1.1 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 OAG36011.1 - 8.4e-06 25.2 0.0 0.00013 21.3 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAG36011.1 - 3.1e-05 24.0 0.1 0.0038 17.2 0.2 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 OAG36011.1 - 0.00096 18.5 0.0 0.28 10.4 0.0 2.5 1 1 2 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase AMP-binding PF00501.28 OAG36012.1 - 1.2e-91 307.4 0.0 1.5e-91 307.1 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG36012.1 - 5.9e-06 27.2 0.0 1.3e-05 26.1 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ECH_1 PF00378.20 OAG36013.1 - 5.9e-48 163.4 0.0 2.8e-33 115.3 0.0 2.1 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAG36013.1 - 1.7e-26 93.5 0.0 7.3e-14 52.0 0.0 3.0 2 1 1 3 3 3 3 Enoyl-CoA hydratase/isomerase Acetyltransf_8 PF13523.6 OAG36014.1 - 3e-40 137.2 0.2 4.7e-40 136.6 0.2 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain ABC_membrane PF00664.23 OAG36015.1 - 3.6e-88 295.8 24.1 1.4e-49 169.3 3.5 2.4 2 1 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 OAG36015.1 - 7.1e-64 214.4 0.0 1.2e-31 110.1 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 OAG36015.1 - 5.2e-14 52.2 0.6 0.00095 18.7 0.0 4.2 2 2 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 OAG36015.1 - 1.7e-08 34.0 0.1 0.0045 16.7 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 OAG36015.1 - 2.3e-07 31.3 1.6 0.014 15.8 0.0 3.4 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 OAG36015.1 - 3.1e-07 30.8 0.4 0.18 12.1 0.0 3.9 3 1 0 3 3 3 2 AAA domain DUF87 PF01935.17 OAG36015.1 - 1.3e-06 28.7 0.1 0.0017 18.5 0.0 2.5 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_21 PF13304.6 OAG36015.1 - 8.8e-06 25.7 0.3 0.26 11.1 0.0 3.8 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 OAG36015.1 - 9.1e-06 25.5 0.3 0.033 13.9 0.0 3.4 3 1 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 OAG36015.1 - 4.5e-05 23.4 0.0 0.047 13.6 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase APS_kinase PF01583.20 OAG36015.1 - 9.2e-05 22.4 0.1 0.065 13.1 0.0 2.5 2 0 0 2 2 2 1 Adenylylsulphate kinase Zeta_toxin PF06414.12 OAG36015.1 - 0.00014 21.2 0.0 0.24 10.7 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_18 PF13238.6 OAG36015.1 - 0.00032 21.3 0.0 0.57 10.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 OAG36015.1 - 0.00063 20.3 0.7 0.8 10.2 0.0 2.7 3 0 0 3 3 3 2 AAA domain ABC_ATPase PF09818.9 OAG36015.1 - 0.0011 17.8 0.1 0.029 13.2 0.0 2.6 3 0 0 3 3 3 1 Predicted ATPase of the ABC class AAA_33 PF13671.6 OAG36015.1 - 0.0029 17.8 0.1 3.9 7.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 OAG36015.1 - 0.0043 17.5 0.7 15 6.1 0.3 4.2 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 OAG36015.1 - 0.0055 16.3 0.1 0.89 9.1 0.0 3.5 4 0 0 4 4 4 1 AAA domain DUF3987 PF13148.6 OAG36015.1 - 0.0059 15.7 0.0 0.61 9.0 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3987) AAA_5 PF07728.14 OAG36015.1 - 0.0086 16.1 0.0 3.1 7.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.23 OAG36015.1 - 0.016 15.3 0.1 6.3 6.9 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase SbcCD_C PF13558.6 OAG36015.1 - 0.036 14.3 1.1 8.2 6.7 0.1 3.2 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit DEAD PF00270.29 OAG36015.1 - 0.067 13.0 0.1 0.45 10.3 0.0 2.3 2 1 0 2 2 2 0 DEAD/DEAH box helicase SRP54 PF00448.22 OAG36015.1 - 0.1 12.2 0.1 18 4.8 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_7 PF12775.7 OAG36015.1 - 0.11 12.0 0.0 18 4.8 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_15 PF13175.6 OAG36015.1 - 0.13 11.9 0.0 15 5.2 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain G-alpha PF00503.20 OAG36015.1 - 0.15 11.2 0.0 13 4.9 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit AMP-binding PF00501.28 OAG36016.1 - 1.3e-76 257.9 0.0 3.9e-73 246.4 0.1 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.20 OAG36016.1 - 7.1e-72 242.5 0.0 4e-38 131.3 0.0 3.3 3 0 0 3 3 3 2 Condensation domain PP-binding PF00550.25 OAG36016.1 - 5.2e-28 97.2 0.6 5.6e-13 49.0 0.0 3.1 3 0 0 3 3 3 2 Phosphopantetheine attachment site AMP-binding_C PF13193.6 OAG36016.1 - 0.024 15.6 1.4 34 5.5 0.0 4.1 4 0 0 4 4 4 0 AMP-binding enzyme C-terminal domain Fungal_trans PF04082.18 OAG36017.1 - 4.5e-17 62.0 1.1 7.6e-17 61.2 1.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.18 OAG36018.1 - 2e-07 30.3 0.4 4e-07 29.3 0.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain AMP-binding PF00501.28 OAG36019.1 - 3.9e-88 295.9 0.0 5e-88 295.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG36019.1 - 8.7e-14 52.3 0.1 2.6e-13 50.7 0.2 1.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain TRI12 PF06609.13 OAG36020.1 - 6.5e-21 74.4 27.6 8.2e-21 74.0 27.6 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG36020.1 - 2e-08 33.5 59.2 4e-05 22.7 10.6 3.9 2 1 1 3 3 3 2 Major Facilitator Superfamily DUF2301 PF10063.9 OAG36020.1 - 0.23 11.9 4.6 4.8 7.6 0.2 2.7 2 0 0 2 2 2 0 Uncharacterized integral membrane protein (DUF2301) RVT_1 PF00078.27 OAG36021.1 - 2.7e-25 89.2 0.1 1.8e-13 50.6 0.0 2.6 2 1 1 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 OAG36021.1 - 1.6e-12 47.4 0.0 3.4e-12 46.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase TetR_C_1 PF02909.17 OAG36023.1 - 0.13 12.1 0.0 0.14 11.9 0.0 1.1 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain OCRE PF17780.1 OAG36025.1 - 0.14 12.2 0.0 0.29 11.2 0.0 1.4 1 0 0 1 1 1 0 OCRE domain Zn_clus PF00172.18 OAG36026.1 - 0.0039 17.3 4.5 0.006 16.7 4.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AIG2_2 PF13772.6 OAG36026.1 - 0.0066 16.8 0.1 0.013 15.9 0.1 1.5 1 0 0 1 1 1 1 AIG2-like family MFS_1 PF07690.16 OAG36027.1 - 2.7e-32 112.1 18.4 2.7e-32 112.1 18.4 1.5 1 1 1 2 2 2 1 Major Facilitator Superfamily Fungal_trans PF04082.18 OAG36028.1 - 6.6e-12 45.0 1.0 1.2e-11 44.1 1.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG36028.1 - 2e-08 34.2 13.2 3.4e-08 33.5 13.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1981 PF09324.10 OAG36028.1 - 0.094 12.6 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1981) VWA PF00092.28 OAG36029.1 - 8.4e-06 26.1 0.0 4.7e-05 23.7 0.0 2.2 2 1 0 2 2 2 1 von Willebrand factor type A domain VWA_2 PF13519.6 OAG36029.1 - 0.0022 18.6 0.1 2.9 8.6 0.0 3.4 2 1 1 3 3 3 1 von Willebrand factor type A domain DUF1194 PF06707.11 OAG36029.1 - 0.0026 17.0 0.0 0.015 14.5 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1194) Peptidase_C1 PF00112.23 OAG36029.1 - 0.01 15.9 0.0 0.045 13.8 0.0 1.9 2 0 0 2 2 2 0 Papain family cysteine protease Ssl1 PF04056.14 OAG36029.1 - 0.13 12.1 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Ssl1-like Gly-zipper_Omp PF13488.6 OAG36029.1 - 0.58 10.2 9.7 1.3 9.1 9.7 1.5 1 0 0 1 1 1 0 Glycine zipper Bacteriocin_IIc PF10439.9 OAG36029.1 - 0.6 10.3 9.6 1.3 9.2 9.6 1.5 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide DUF1269 PF06897.12 OAG36029.1 - 1.1 9.5 3.1 3.3 8.1 3.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) TPR_12 PF13424.6 OAG36030.1 - 1.2e-36 124.8 7.5 7.3e-14 51.8 0.5 5.7 3 2 3 6 6 6 6 Tetratricopeptide repeat TPR_10 PF13374.6 OAG36030.1 - 7.4e-32 108.3 1.1 6.1e-08 32.3 0.1 6.3 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_1 PF00515.28 OAG36030.1 - 2.2e-18 65.2 9.3 0.0016 18.2 0.0 6.9 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.17 OAG36030.1 - 2.5e-14 52.2 12.0 0.13 12.4 0.2 7.4 7 0 0 7 7 6 5 Tetratricopeptide repeat TPR_8 PF13181.6 OAG36030.1 - 6.8e-14 50.8 10.4 0.16 12.3 0.2 6.8 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_7 PF13176.6 OAG36030.1 - 8.9e-13 47.3 2.7 0.091 12.8 0.0 6.5 6 0 0 6 6 6 3 Tetratricopeptide repeat HET PF06985.11 OAG36030.1 - 4.6e-11 43.3 10.0 3e-09 37.4 1.4 2.6 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) TPR_MalT PF17874.1 OAG36030.1 - 1.5e-07 31.2 1.1 8.2e-07 28.7 0.3 2.4 1 1 1 2 2 2 1 MalT-like TPR region TPR_19 PF14559.6 OAG36030.1 - 5.9e-07 29.9 0.2 7.9e-05 23.1 0.2 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 OAG36030.1 - 4.8e-05 23.8 0.3 3.5 8.7 0.0 5.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 OAG36030.1 - 0.00018 22.1 0.9 1.1 9.9 0.0 4.8 3 1 0 4 4 3 1 Tetratricopeptide repeat DUF2225 PF09986.9 OAG36030.1 - 0.00023 21.0 3.1 0.038 13.7 1.3 3.2 3 0 0 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2225) NB-ARC PF00931.22 OAG36030.1 - 0.0016 17.7 0.1 0.075 12.2 0.1 2.3 1 1 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 OAG36030.1 - 0.0024 18.3 0.0 0.012 16.0 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain TPR_6 PF13174.6 OAG36030.1 - 0.0071 16.9 5.1 6.5 7.6 0.1 5.2 6 0 0 6 6 5 1 Tetratricopeptide repeat PPR PF01535.20 OAG36030.1 - 0.0083 16.3 2.6 13 6.3 0.0 5.2 6 0 0 6 6 6 0 PPR repeat RPN7 PF10602.9 OAG36030.1 - 0.015 15.0 0.1 6.4 6.5 0.0 3.5 1 1 3 4 4 4 0 26S proteasome subunit RPN7 BRO1 PF03097.18 OAG36030.1 - 0.025 13.4 0.8 0.081 11.7 0.3 1.9 2 0 0 2 2 2 0 BRO1-like domain TPR_17 PF13431.6 OAG36030.1 - 0.054 13.9 0.7 76 4.0 0.0 4.6 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 OAG36030.1 - 0.067 12.9 6.7 56 3.5 0.1 5.9 6 0 0 6 6 6 0 TPR repeat TPR_4 PF07721.14 OAG36030.1 - 0.15 12.8 3.5 6.1 7.8 0.0 4.1 4 0 0 4 4 3 0 Tetratricopeptide repeat MIT PF04212.18 OAG36030.1 - 0.97 9.5 8.4 13 5.9 0.7 5.1 5 1 1 6 6 5 0 MIT (microtubule interacting and transport) domain DUF2439 PF10382.9 OAG36034.1 - 0.045 14.1 0.5 0.42 11.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2439) Pkinase PF00069.25 OAG36035.1 - 7.8e-42 143.4 0.0 1.1e-41 143.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG36035.1 - 1.1e-22 80.6 0.0 2.6e-22 79.4 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 OAG36035.1 - 4.3e-05 23.8 0.0 0.0001 22.6 0.0 1.7 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 OAG36035.1 - 0.0023 18.2 0.0 0.0052 17.1 0.0 1.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Pox_ser-thr_kin PF05445.11 OAG36035.1 - 0.14 11.1 0.0 0.21 10.5 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase CHAT PF12770.7 OAG36036.1 - 8.7e-36 123.8 0.4 1.7e-35 122.9 0.1 1.6 2 0 0 2 2 2 1 CHAT domain TPR_10 PF13374.6 OAG36036.1 - 1.1e-07 31.5 17.8 1.2 9.1 0.2 9.2 8 1 0 8 8 8 3 Tetratricopeptide repeat TPR_12 PF13424.6 OAG36036.1 - 1.1e-07 32.1 16.9 4.6 7.6 0.4 9.1 5 3 4 9 9 9 3 Tetratricopeptide repeat TPR_14 PF13428.6 OAG36036.1 - 5.6e-05 23.6 15.3 20 6.3 0.1 9.1 8 1 1 9 9 9 0 Tetratricopeptide repeat SMBP PF16785.5 OAG36036.1 - 0.0046 17.1 8.7 5.1 7.4 0.1 5.0 4 1 0 4 4 4 1 Small metal-binding protein TPR_11 PF13414.6 OAG36036.1 - 0.044 13.5 5.6 6.2 6.6 0.3 4.8 3 2 0 3 3 3 0 TPR repeat TPR_17 PF13431.6 OAG36036.1 - 0.074 13.5 2.2 38 5.0 0.1 4.9 5 0 0 5 5 4 0 Tetratricopeptide repeat DUF4071 PF13281.6 OAG36036.1 - 0.092 11.8 0.1 1.4 7.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4071) TPR_8 PF13181.6 OAG36036.1 - 0.29 11.4 12.0 98 3.6 0.0 7.9 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_6 PF13174.6 OAG36036.1 - 0.57 10.9 5.9 25 5.8 0.0 6.1 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_2 PF07719.17 OAG36036.1 - 1.6 9.1 13.7 46 4.5 0.0 7.7 9 1 0 9 9 9 0 Tetratricopeptide repeat Peptidase_C14 PF00656.22 OAG36037.1 - 1.6e-15 57.7 0.0 3.2e-15 56.8 0.0 1.5 1 0 0 1 1 1 1 Caspase domain Peptidase_C13 PF01650.18 OAG36037.1 - 0.02 14.4 0.1 0.3 10.6 0.1 2.1 1 1 0 1 1 1 0 Peptidase C13 family Raptor_N PF14538.6 OAG36037.1 - 0.16 11.9 0.0 0.44 10.5 0.0 1.7 2 0 0 2 2 2 0 Raptor N-terminal CASPase like domain DUF4579 PF15158.6 OAG36039.1 - 0.16 11.7 0.2 0.25 11.1 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4579) DUF3093 PF11292.8 OAG36039.1 - 0.38 11.0 5.8 13 6.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3093) DUF751 PF05421.11 OAG36039.1 - 4.4 8.1 8.1 2.1 9.1 5.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF751) DnaJ_C PF01556.18 OAG36041.1 - 5.7e-25 88.1 0.1 8.1e-25 87.6 0.1 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 OAG36041.1 - 2.3e-21 75.7 0.9 4.1e-21 74.9 0.9 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 OAG36041.1 - 6.4e-13 48.9 19.8 1.1e-12 48.1 19.8 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 OAG36041.1 - 0.0037 17.2 10.8 0.016 15.2 1.9 2.4 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 OAG36041.1 - 0.021 14.9 8.0 0.85 9.7 1.0 2.3 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Lar_restr_allev PF14354.6 OAG36041.1 - 2.2 8.7 8.8 2.8 8.4 5.7 2.7 2 1 1 3 3 3 0 Restriction alleviation protein Lar DZR PF12773.7 OAG36041.1 - 7.2 6.7 12.3 5.5 7.1 2.2 2.2 1 1 1 2 2 2 0 Double zinc ribbon ADK_lid PF05191.14 OAG36041.1 - 8.7 6.4 8.7 61 3.7 0.0 4.1 4 0 0 4 4 4 0 Adenylate kinase, active site lid Ubiq_cyt_C_chap PF03981.12 OAG36043.1 - 8.3e-30 103.7 0.5 1.5e-28 99.6 0.6 2.1 2 0 0 2 2 2 1 Ubiquinol-cytochrome C chaperone Ferritin_2 PF13668.6 OAG36044.1 - 1.9e-20 73.4 0.1 3.2e-20 72.7 0.1 1.4 1 0 0 1 1 1 1 Ferritin-like domain TPR_12 PF13424.6 OAG36045.1 - 5e-05 23.5 2.2 0.04 14.2 0.4 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat Bromo_TP PF07524.13 OAG36047.1 - 1.9e-10 40.6 0.0 3e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated TFIID-31kDa PF02291.15 OAG36047.1 - 0.014 15.5 0.0 0.022 14.8 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit TAFII55_N PF04658.13 OAG36048.1 - 9.3e-46 155.5 0.0 1.9e-45 154.4 0.0 1.6 1 0 0 1 1 1 1 TAFII55 protein conserved region Sigma70_ner PF04546.13 OAG36048.1 - 0.002 18.1 9.3 0.002 18.1 9.3 2.3 2 0 0 2 2 2 1 Sigma-70, non-essential region BLOC1S3 PF15753.5 OAG36048.1 - 0.065 13.4 10.2 0.21 11.7 6.8 2.5 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 DUF1664 PF07889.12 OAG36048.1 - 0.85 9.7 6.1 0.33 11.0 3.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) GBP_C PF02841.14 OAG36048.1 - 1.7 8.0 7.3 2.8 7.3 7.3 1.3 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain UPF0242 PF06785.11 OAG36048.1 - 1.8 8.6 7.2 3.2 7.8 7.2 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus GCIP PF13324.6 OAG36048.1 - 2 7.9 10.8 0.24 11.0 6.2 1.7 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting NOA36 PF06524.12 OAG36048.1 - 6.9 5.9 16.8 0.83 8.9 6.9 3.2 2 1 0 3 3 3 0 NOA36 protein RRN3 PF05327.11 OAG36048.1 - 8.6 4.8 6.1 13 4.2 6.1 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Pox_RNA_Pol_19 PF05320.12 OAG36048.1 - 9.8 6.1 8.4 24 4.9 8.4 1.6 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit HET PF06985.11 OAG36049.1 - 0.012 16.0 2.6 0.018 15.4 0.2 2.2 1 1 1 2 2 2 0 Heterokaryon incompatibility protein (HET) Fungal_trans PF04082.18 OAG36050.1 - 1.2e-12 47.4 0.1 2.8e-12 46.2 0.1 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG36050.1 - 1e-08 35.2 9.6 1.9e-08 34.3 9.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 OAG36051.1 - 2.2e-42 145.3 41.5 4.9e-42 144.1 41.5 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily p450 PF00067.22 OAG36052.1 - 1.4e-51 175.7 0.0 1.8e-51 175.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1993 PF09351.10 OAG36052.1 - 0.084 13.0 0.4 0.2 11.8 0.4 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1993) TRI12 PF06609.13 OAG36053.1 - 2.1e-23 82.6 22.1 3.2e-23 82.0 22.1 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG36053.1 - 2.2e-19 69.6 40.6 2.2e-19 69.6 40.6 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF2181 PF10223.9 OAG36053.1 - 0.2 11.1 0.1 0.4 10.1 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2181) DUF4017 PF13209.6 OAG36053.1 - 0.26 11.3 3.6 0.48 10.4 0.7 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4017) GST_C PF00043.25 OAG36054.1 - 0.00022 21.4 0.0 0.00034 20.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OAG36054.1 - 0.0026 17.7 0.1 0.0066 16.4 0.1 1.8 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain CAF-1_p60_C PF15512.6 OAG36054.1 - 0.19 12.2 0.0 0.65 10.5 0.0 1.8 2 0 0 2 2 2 0 Chromatin assembly factor complex 1 subunit p60, C-terminal CAAP1 PF15335.6 OAG36055.1 - 0.083 13.5 0.7 0.14 12.7 0.7 1.3 1 0 0 1 1 1 0 Caspase activity and apoptosis inhibitor 1 OAD_gamma PF04277.13 OAG36056.1 - 0.31 11.7 4.9 0.76 10.4 0.0 3.1 2 1 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain PTR2 PF00854.21 OAG36057.1 - 3.4e-91 306.0 5.2 8.4e-91 304.7 5.2 1.6 1 1 0 1 1 1 1 POT family MFS_1 PF07690.16 OAG36057.1 - 6e-05 22.1 20.7 6e-05 22.1 20.7 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF4094 PF13334.6 OAG36057.1 - 0.024 15.1 0.2 5.4 7.5 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) Pkinase PF00069.25 OAG36058.1 - 6.7e-60 202.7 0.0 8.6e-39 133.5 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAG36058.1 - 1.5e-26 93.3 0.0 2.6e-20 72.8 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.24 OAG36058.1 - 4e-12 46.3 0.0 1e-11 45.0 0.0 1.8 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.6 OAG36058.1 - 6.7e-08 32.2 0.0 4.1e-05 23.0 0.0 2.4 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 OAG36058.1 - 5.3e-05 23.3 0.2 0.0032 17.4 0.1 3.1 3 1 1 4 4 4 1 Phosphotransferase enzyme family Kdo PF06293.14 OAG36058.1 - 0.0081 15.5 0.0 0.016 14.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OAG36058.1 - 0.011 14.7 0.4 0.02 13.8 0.0 1.6 2 0 0 2 2 2 0 Haspin like kinase domain FTA2 PF13095.6 OAG36058.1 - 0.037 13.7 0.0 11 5.6 0.0 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 PAS_4 PF08448.10 OAG36058.1 - 0.084 13.1 0.0 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 PAS fold PAS PF00989.25 OAG36058.1 - 0.085 12.9 0.0 0.21 11.6 0.0 1.7 1 0 0 1 1 1 0 PAS fold Seadorna_VP7 PF07387.11 OAG36058.1 - 0.13 11.2 0.1 0.22 10.5 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 PAS_9 PF13426.7 OAG36058.1 - 0.19 12.0 0.0 0.56 10.5 0.0 1.7 1 0 0 1 1 1 0 PAS domain 3Beta_HSD PF01073.19 OAG36059.1 - 3.3e-41 141.1 0.0 1.2e-36 126.1 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 OAG36059.1 - 6.9e-18 65.0 0.0 1e-14 54.6 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAG36059.1 - 2.4e-11 43.6 0.0 1.2e-08 34.7 0.0 2.5 3 0 0 3 3 3 2 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 OAG36059.1 - 1.3e-10 40.9 0.0 1.1e-07 31.3 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 OAG36059.1 - 1.2e-07 31.1 0.1 5.9e-07 28.9 0.0 1.9 2 0 0 2 2 2 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 OAG36059.1 - 0.0025 17.0 0.0 1.5 7.9 0.0 2.9 3 0 0 3 3 3 2 Polysaccharide biosynthesis protein Ribosomal_L5e PF17144.4 OAG36059.1 - 0.04 13.9 0.0 0.073 13.1 0.0 1.3 1 0 0 1 1 1 0 Ribosomal large subunit proteins 60S L5, and 50S L18 UQ_con PF00179.26 OAG36060.1 - 1.2e-42 144.9 0.0 3.8e-29 101.1 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OAG36060.1 - 8.8e-08 31.9 0.0 0.00058 19.6 0.0 2.4 2 0 0 2 2 2 2 Prokaryotic E2 family B UEV PF05743.13 OAG36060.1 - 0.013 15.3 0.0 0.037 13.9 0.0 1.7 1 0 0 1 1 1 0 UEV domain RWD PF05773.22 OAG36060.1 - 0.081 13.2 0.0 2.6 8.3 0.0 2.4 2 0 0 2 2 2 0 RWD domain HATPase_c PF02518.26 OAG36061.1 - 9e-27 93.8 0.2 1.8e-26 92.9 0.2 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 OAG36061.1 - 1.1e-19 70.2 0.1 3.1e-19 68.8 0.1 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Response_reg PF00072.24 OAG36061.1 - 1.1e-16 61.0 0.1 3.5e-16 59.4 0.1 1.9 1 0 0 1 1 1 1 Response regulator receiver domain PAS_3 PF08447.12 OAG36061.1 - 4.6e-15 55.7 0.4 4.4e-14 52.5 0.5 2.5 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.10 OAG36061.1 - 8.4e-11 42.1 0.0 5.2e-07 29.9 0.0 4.4 4 1 0 4 4 4 1 PAS fold PAS_9 PF13426.7 OAG36061.1 - 4.3e-10 39.8 0.0 0.00012 22.3 0.0 4.5 4 0 0 4 4 4 2 PAS domain PAS PF00989.25 OAG36061.1 - 4.4e-07 29.9 0.0 0.04 13.9 0.0 3.8 3 0 0 3 3 3 2 PAS fold MLTR_LBD PF17765.1 OAG36061.1 - 0.07 13.2 0.1 0.19 11.9 0.1 1.7 1 0 0 1 1 1 0 MmyB-like transcription regulator ligand binding domain HATPase_c_3 PF13589.6 OAG36061.1 - 0.12 12.3 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF4172 PF13776.6 OAG36061.1 - 0.12 12.7 0.2 0.32 11.4 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4172) Ldi PF18566.1 OAG36062.1 - 1.4e-135 451.9 0.1 1.6e-134 448.4 0.1 2.0 1 1 0 1 1 1 1 Linalool dehydratase/isomerase MFS_1 PF07690.16 OAG36063.1 - 2.4e-36 125.4 64.3 6.8e-36 123.9 62.2 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG36063.1 - 9.3e-08 31.3 17.3 9.3e-08 31.3 17.3 2.7 2 2 0 2 2 2 1 Sugar (and other) transporter DUF1700 PF08006.11 OAG36063.1 - 0.17 11.4 11.0 1.5 8.3 2.7 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1700) AMP-binding PF00501.28 OAG36065.1 - 9.4e-91 304.5 0.0 1.2e-90 304.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG36065.1 - 1.7e-12 48.1 0.0 9.8e-12 45.7 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ADH_N_2 PF16884.5 OAG36066.1 - 3.7e-12 46.1 0.0 9.7e-12 44.7 0.0 1.6 2 0 0 2 2 2 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 OAG36066.1 - 1e-08 35.2 0.0 1.5e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase zf-RING_2 PF13639.6 OAG36067.1 - 9.8e-10 38.6 7.5 1.7e-09 37.9 7.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 OAG36067.1 - 1.8e-06 27.7 8.0 3e-06 26.9 8.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAG36067.1 - 2.1e-06 27.5 5.9 3.4e-06 26.8 5.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OAG36067.1 - 2.2e-06 27.4 7.7 3.6e-06 26.7 7.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OAG36067.1 - 3.5e-05 24.0 9.3 0.00019 21.7 9.3 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain POTRA_TamA_1 PF17243.2 OAG36067.1 - 0.086 12.9 0.3 1 9.5 0.0 2.6 3 0 0 3 3 3 0 POTRA domain TamA domain 1 zf-RING_11 PF17123.5 OAG36067.1 - 0.089 12.6 6.5 0.22 11.3 6.5 1.7 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_5 PF14634.6 OAG36067.1 - 0.18 11.8 9.4 0.3 11.1 9.4 1.4 1 0 0 1 1 1 0 zinc-RING finger domain Mpv17_PMP22 PF04117.12 OAG36068.1 - 1.6e-15 57.1 11.5 3.4e-15 56.0 11.5 1.6 1 0 0 1 1 1 1 Mpv17 / PMP22 family IncD PF17628.2 OAG36069.1 - 0.011 15.5 2.1 0.011 15.5 2.1 1.8 2 0 0 2 2 2 0 Inclusion membrane protein D RTA1 PF04479.13 OAG36069.1 - 0.019 14.6 9.7 0.021 14.4 8.4 1.8 1 1 0 1 1 1 0 RTA1 like protein TM_helix PF05552.12 OAG36069.1 - 0.26 11.3 4.5 2.3 8.3 0.2 2.7 2 0 0 2 2 2 0 Conserved TM helix DUF4064 PF13273.6 OAG36069.1 - 0.66 10.3 10.6 0.16 12.3 3.5 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) DUF4199 PF13858.6 OAG36069.1 - 1 9.7 9.3 0.099 13.0 4.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) Sel1 PF08238.12 OAG36070.1 - 1.4e-22 79.6 19.3 6.8e-08 32.9 0.1 6.6 7 0 0 7 7 7 5 Sel1 repeat Helicase_C_2 PF13307.6 OAG36071.1 - 1.7e-51 174.8 0.0 4.5e-51 173.4 0.0 1.7 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 OAG36071.1 - 3e-47 160.5 0.0 5e-47 159.8 0.0 1.4 1 0 0 1 1 1 1 DEAD_2 HBB PF06777.11 OAG36071.1 - 0.00028 20.6 0.0 0.00089 19.0 0.0 1.9 1 0 0 1 1 1 1 Helical and beta-bridge domain ResIII PF04851.15 OAG36071.1 - 0.0024 17.9 0.5 2.5 8.1 0.1 2.9 2 2 0 2 2 2 2 Type III restriction enzyme, res subunit Brix PF04427.18 OAG36071.1 - 0.029 14.5 0.0 0.064 13.3 0.0 1.7 1 1 0 1 1 1 0 Brix domain PhoH PF02562.16 OAG36071.1 - 0.032 13.7 0.0 9.6 5.6 0.0 2.6 2 1 0 2 2 2 0 PhoH-like protein DEAD PF00270.29 OAG36071.1 - 0.064 13.0 0.1 11 5.8 0.0 2.6 2 1 0 2 2 2 0 DEAD/DEAH box helicase AAA_22 PF13401.6 OAG36071.1 - 0.13 12.5 0.1 3.6 7.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain V-ATPase_G_2 PF16999.5 OAG36072.1 - 6.4e-05 23.3 9.9 8.4e-05 22.9 9.9 1.2 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit Apolipoprotein PF01442.18 OAG36072.1 - 0.00022 21.1 4.5 0.00028 20.8 4.5 1.0 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF883 PF05957.13 OAG36072.1 - 0.0063 17.1 3.3 0.0063 17.1 3.3 1.8 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF883) DUF4200 PF13863.6 OAG36072.1 - 0.34 11.3 10.8 0.96 9.9 11.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) OmpH PF03938.14 OAG36072.1 - 0.35 11.2 10.2 0.46 10.8 10.2 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF809 PF05663.11 OAG36072.1 - 0.49 10.5 2.4 0.57 10.3 2.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF809) ATP-synt_B PF00430.18 OAG36072.1 - 4.4 7.4 14.8 5.6 7.1 13.8 1.6 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) Z1 PF10593.9 OAG36072.1 - 4.8 6.6 5.4 18 4.8 0.1 2.1 2 0 0 2 2 2 0 Z1 domain LsmAD PF06741.13 OAG36072.1 - 7.2 7.2 9.3 1.8 9.2 2.5 2.4 1 1 1 2 2 2 0 LsmAD domain Pex24p PF06398.11 OAG36073.1 - 4.2e-07 29.3 10.0 6.8e-07 28.6 10.0 1.4 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin CDT1_C PF16679.5 OAG36074.1 - 1.6e-12 47.7 0.0 4.9e-12 46.1 0.0 1.9 1 0 0 1 1 1 1 DNA replication factor Cdt1 C-terminal domain FliG_C PF01706.16 OAG36074.1 - 0.046 13.9 1.6 1.9 8.7 0.1 2.5 2 0 0 2 2 2 0 FliG C-terminal domain Herpes_TK_C PF08465.10 OAG36074.1 - 0.056 13.2 0.1 0.13 12.0 0.1 1.6 1 0 0 1 1 1 0 Thymidine kinase from Herpesvirus C-terminal DTHCT PF08070.11 OAG36074.1 - 0.26 12.0 7.7 0.65 10.8 7.7 1.7 1 0 0 1 1 1 0 DTHCT (NUC029) region FMN_dh PF01070.18 OAG36075.1 - 3.2e-119 398.0 0.0 4.1e-119 397.7 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 OAG36075.1 - 2.5e-10 39.9 1.2 7.5e-08 31.7 0.2 2.7 2 1 1 3 3 3 2 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 OAG36075.1 - 5e-05 22.9 0.7 8.2e-05 22.1 0.7 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase Glu_synthase PF01645.17 OAG36075.1 - 9.6e-05 21.7 0.0 0.00023 20.4 0.1 1.6 2 0 0 2 2 2 1 Conserved region in glutamate synthase His_biosynth PF00977.21 OAG36075.1 - 0.0024 17.4 0.3 0.045 13.2 0.0 2.6 2 1 1 3 3 3 1 Histidine biosynthesis protein ThiG PF05690.14 OAG36075.1 - 0.03 13.6 0.7 0.95 8.7 0.1 2.7 2 1 1 3 3 3 0 Thiazole biosynthesis protein ThiG PAP2_3 PF14378.6 OAG36076.1 - 5.3e-25 88.2 16.0 1.1e-24 87.2 16.0 1.5 1 0 0 1 1 1 1 PAP2 superfamily PAP2 PF01569.21 OAG36076.1 - 4e-10 39.6 7.6 4e-10 39.6 7.6 2.2 2 0 0 2 2 2 1 PAP2 superfamily DUF4330 PF14221.6 OAG36077.1 - 0.009 16.2 0.4 0.011 16.0 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4330) DUF4148 PF13663.6 OAG36077.1 - 0.018 15.2 0.6 0.05 13.8 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) FA_desaturase PF00487.24 OAG36077.1 - 0.022 14.6 0.0 0.026 14.4 0.0 1.1 1 0 0 1 1 1 0 Fatty acid desaturase EIID-AGA PF03613.14 OAG36077.1 - 0.057 12.6 0.1 0.069 12.3 0.1 1.1 1 0 0 1 1 1 0 PTS system mannose/fructose/sorbose family IID component Arch_flagellin PF01917.16 OAG36077.1 - 0.081 13.1 0.3 0.088 13.0 0.3 1.3 1 0 0 1 1 1 0 Archaebacterial flagellin MitoNEET_N PF10660.9 OAG36077.1 - 0.16 12.0 0.8 0.25 11.4 0.8 1.3 1 0 0 1 1 1 0 Iron-containing outer mitochondrial membrane protein N-terminus TM231 PF10149.9 OAG36077.1 - 0.19 11.1 0.0 0.21 10.9 0.0 1.0 1 0 0 1 1 1 0 Transmembrane protein 231 DUF4307 PF14155.6 OAG36077.1 - 0.44 10.4 8.8 3.4 7.5 0.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4307) Epiglycanin_C PF14654.6 OAG36077.1 - 1.2 9.2 6.6 6 7.0 6.6 2.3 1 1 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region FeoB_associated PF12669.7 OAG36077.1 - 2.4 8.6 3.7 4.2 7.8 3.7 1.4 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein LCAT PF02450.15 OAG36078.1 - 2.9e-105 352.7 0.1 3.8e-105 352.3 0.1 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Lipase_2 PF01674.18 OAG36078.1 - 0.00018 21.1 0.1 0.00068 19.2 0.0 1.9 2 0 0 2 2 2 1 Lipase (class 2) DUF1749 PF08538.10 OAG36078.1 - 0.097 11.7 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Acetyltransf_1 PF00583.25 OAG36079.1 - 7.6e-19 68.1 0.0 1.1e-18 67.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 OAG36079.1 - 9.7e-11 41.5 0.1 3.4e-10 39.7 0.0 1.9 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_10 PF13673.7 OAG36079.1 - 5.5e-10 39.3 0.0 8.3e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OAG36079.1 - 4.7e-09 36.6 0.0 7.3e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 OAG36079.1 - 6.3e-08 33.4 0.0 8.6e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 OAG36079.1 - 9e-06 25.4 0.0 1.4e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 OAG36079.1 - 0.0058 16.7 0.0 0.015 15.4 0.0 1.7 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 OAG36079.1 - 0.0087 16.1 0.0 0.017 15.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_18 PF18014.1 OAG36079.1 - 0.13 12.1 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain SRPRB PF09439.10 OAG36080.1 - 4.2e-22 78.4 0.2 2.6e-20 72.6 0.2 2.1 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.21 OAG36080.1 - 0.00014 21.3 0.0 0.003 17.0 0.0 2.4 2 1 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OAG36080.1 - 0.00058 19.9 0.2 0.0013 18.7 0.2 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OAG36080.1 - 0.009 15.6 0.0 0.045 13.3 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OAG36080.1 - 0.013 15.4 0.5 0.34 10.8 0.1 2.6 3 0 0 3 3 3 0 RsgA GTPase AAA_16 PF13191.6 OAG36080.1 - 0.015 15.7 0.6 0.026 14.9 0.3 1.6 1 1 1 2 2 2 0 AAA ATPase domain ABC_tran PF00005.27 OAG36080.1 - 0.072 13.6 0.4 0.26 11.8 0.4 2.0 1 1 0 1 1 1 0 ABC transporter cobW PF02492.19 OAG36080.1 - 0.083 12.5 0.1 7 6.2 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Roc PF08477.13 OAG36080.1 - 0.11 12.8 0.2 0.62 10.3 0.0 2.1 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 OAG36080.1 - 0.14 11.9 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain KRE9 PF05390.11 OAG36081.1 - 1.2e-14 54.9 8.4 1.2e-14 54.9 8.4 1.7 2 0 0 2 2 2 1 Yeast cell wall synthesis protein KRE9/KNH1 GPI-anchored PF10342.9 OAG36081.1 - 3.5e-11 43.7 0.6 8.1e-11 42.5 0.0 1.8 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Peptidase_M76 PF09768.9 OAG36082.1 - 1.1e-65 220.6 3.4 1.3e-65 220.4 3.4 1.0 1 0 0 1 1 1 1 Peptidase M76 family SprT-like PF10263.9 OAG36082.1 - 0.001 18.9 0.2 0.002 17.9 0.2 1.5 1 0 0 1 1 1 1 SprT-like family Peptidase_M91 PF14891.6 OAG36082.1 - 0.0015 18.9 0.0 0.002 18.5 0.0 1.2 1 0 0 1 1 1 1 Effector protein BSP PF04450.12 OAG36082.1 - 0.051 13.4 0.0 0.078 12.8 0.0 1.3 1 0 0 1 1 1 0 Peptidase of plants and bacteria DA1-like PF12315.8 OAG36082.1 - 0.068 12.5 0.1 0.12 11.8 0.1 1.3 1 0 0 1 1 1 0 Protein DA1 AA_kinase PF00696.28 OAG36083.1 - 3.3e-38 131.7 2.7 4.3e-38 131.3 2.7 1.2 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.20 OAG36083.1 - 1.3e-16 60.3 1.2 2.6e-16 59.4 0.1 2.1 2 1 0 2 2 2 1 PUA domain Nucleotid_trans PF03407.16 OAG36083.1 - 0.097 12.6 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase UL16 PF17622.2 OAG36083.1 - 0.11 12.1 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 Viral unique long protein 16 Cupin_1 PF00190.22 OAG36084.1 - 1.3e-15 57.3 1.1 2.2e-15 56.5 1.1 1.3 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 OAG36084.1 - 0.00058 19.5 0.0 0.00099 18.8 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Na_Ca_ex PF01699.24 OAG36084.1 - 0.0014 18.6 0.8 0.0027 17.7 0.8 1.4 1 0 0 1 1 1 1 Sodium/calcium exchanger protein MIT PF04212.18 OAG36085.1 - 3.2e-12 46.3 1.6 5.7e-12 45.5 1.6 1.4 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Ada_Zn_binding PF02805.16 OAG36086.1 - 3.6e-28 97.4 4.2 5.7e-28 96.7 4.2 1.3 1 0 0 1 1 1 1 Metal binding domain of Ada HTH_18 PF12833.7 OAG36086.1 - 0.0017 18.5 0.0 0.0043 17.3 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 OAG36086.1 - 0.0037 17.3 0.0 0.0072 16.4 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family Flavin_Reduct PF01613.18 OAG36087.1 - 4.3e-11 43.1 0.0 6.2e-11 42.6 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain DUF447 PF04289.12 OAG36087.1 - 0.049 13.4 0.0 0.081 12.7 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF447) Putative_PNPOx PF01243.20 OAG36087.1 - 0.084 13.1 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase GST_N PF02798.20 OAG36088.1 - 2.6e-13 50.1 0.0 1.7e-12 47.5 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OAG36088.1 - 1e-12 48.1 0.1 2.3e-12 47.0 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 OAG36088.1 - 4.2e-11 43.1 0.0 1.2e-10 41.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OAG36088.1 - 1.3e-07 31.8 0.0 4e-07 30.2 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAG36088.1 - 2.2e-06 27.6 0.4 5.7e-06 26.3 0.4 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OAG36088.1 - 4.9e-06 26.6 0.0 1.4e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain FAD_binding_4 PF01565.23 OAG36089.1 - 1.3e-26 93.0 0.0 2.1e-26 92.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.19 OAG36089.1 - 3e-11 43.4 0.7 4e-11 43.0 0.0 1.6 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain FSH1 PF03959.13 OAG36090.1 - 2.8e-27 95.8 0.0 3.7e-27 95.4 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 OAG36090.1 - 0.014 16.0 0.2 0.019 15.6 0.2 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Imm74 PF15603.6 OAG36090.1 - 0.047 13.9 0.1 0.088 13.0 0.1 1.4 1 0 0 1 1 1 0 Immunity protein 74 Abhydrolase_2 PF02230.16 OAG36090.1 - 0.048 13.5 0.0 0.21 11.4 0.0 1.9 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase NB-ARC PF00931.22 OAG36091.1 - 1.2e-07 31.2 0.0 1.9e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_5 PF07728.14 OAG36091.1 - 0.00031 20.7 0.0 0.0011 19.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OAG36091.1 - 0.00044 20.7 0.0 0.0011 19.4 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 OAG36091.1 - 0.041 14.3 0.0 0.083 13.3 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 OAG36091.1 - 0.092 12.9 0.0 0.22 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 OAG36091.1 - 0.15 12.6 0.0 0.33 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 OAG36091.1 - 0.17 11.3 0.0 0.32 10.4 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ECH_1 PF00378.20 OAG36093.1 - 3.8e-40 137.8 0.0 6.4e-40 137.0 0.0 1.3 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAG36093.1 - 4.2e-28 98.8 0.0 4.8e-28 98.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase DUF4440 PF14534.6 OAG36094.1 - 4.5e-10 39.9 0.0 5.2e-10 39.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) CARD PF00619.21 OAG36094.1 - 0.033 14.2 0.0 0.054 13.5 0.0 1.3 1 0 0 1 1 1 0 Caspase recruitment domain CsbD PF05532.12 OAG36095.1 - 0.00035 20.4 14.3 0.0012 18.7 9.3 2.4 1 1 1 2 2 2 2 CsbD-like LEA_4 PF02987.16 OAG36095.1 - 0.17 12.0 17.5 0.74 9.9 0.4 2.7 3 1 0 3 3 3 0 Late embryogenesis abundant protein DnaJ PF00226.31 OAG36096.1 - 3e-10 40.1 0.5 6e-10 39.1 0.5 1.6 1 0 0 1 1 1 1 DnaJ domain FHA PF00498.26 OAG36097.1 - 1.5e-16 60.5 0.0 2.5e-16 59.7 0.0 1.4 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 OAG36097.1 - 0.00086 19.6 0.0 0.038 14.3 0.0 2.3 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Aminotran_5 PF00266.19 OAG36098.1 - 1.3e-25 90.2 0.0 2.1e-25 89.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V 2-Hacid_dh_C PF02826.19 OAG36099.1 - 1.2e-44 151.9 0.0 1.7e-44 151.3 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 OAG36099.1 - 0.0022 17.7 0.0 0.0088 15.7 0.0 2.1 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain DUF1485 PF07364.12 OAG36100.1 - 6.4e-102 340.7 0.0 8.1e-102 340.4 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M81 MlrC_C PF07171.12 OAG36100.1 - 7.3e-57 192.4 0.1 1.2e-56 191.7 0.1 1.3 1 0 0 1 1 1 1 MlrC C-terminus Sugar_tr PF00083.24 OAG36101.1 - 3e-55 187.9 12.1 1e-38 133.4 0.4 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 OAG36101.1 - 5e-20 71.7 26.0 3.9e-16 58.9 11.7 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 OAG36101.1 - 2.8e-05 22.9 4.0 2.8e-05 22.9 4.0 3.2 2 1 0 3 3 3 2 MFS/sugar transport protein TRI12 PF06609.13 OAG36101.1 - 0.00042 18.9 1.2 0.00042 18.9 1.2 1.9 3 0 0 3 3 3 1 Fungal trichothecene efflux pump (TRI12) PUCC PF03209.15 OAG36101.1 - 0.001 18.2 3.3 0.001 18.2 3.3 1.9 2 1 0 2 2 2 1 PUCC protein Tannase PF07519.11 OAG36102.1 - 2.8e-95 320.0 0.1 3.5e-95 319.7 0.1 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase CBM_2 PF00553.19 OAG36102.1 - 0.034 14.5 0.6 0.092 13.1 0.6 1.8 1 0 0 1 1 1 0 Cellulose binding domain DUF169 PF02596.15 OAG36103.1 - 0.15 12.0 0.0 0.15 12.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised ArCR, COG2043 ADH_N PF08240.12 OAG36104.1 - 9e-25 86.7 3.3 5.1e-24 84.3 0.4 2.6 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG36104.1 - 4e-16 59.2 0.1 7.1e-16 58.4 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Fungal_trans PF04082.18 OAG36104.1 - 2e-14 53.3 0.1 3.6e-14 52.4 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG36104.1 - 0.0014 18.7 2.2 0.0014 18.7 2.2 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AlaDh_PNT_C PF01262.21 OAG36104.1 - 0.018 14.3 0.4 0.035 13.4 0.4 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Cyt-b5 PF00173.28 OAG36105.1 - 9.8e-22 76.9 0.1 1.4e-21 76.4 0.1 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain SPW PF03779.14 OAG36105.1 - 0.084 12.5 0.2 0.16 11.5 0.1 1.6 2 0 0 2 2 2 0 SPW repeat adh_short_C2 PF13561.6 OAG36106.1 - 6.6e-56 189.5 0.7 1.1e-55 188.8 0.7 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG36106.1 - 6.6e-47 159.5 2.6 1.2e-46 158.7 2.6 1.3 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG36106.1 - 1.3e-06 28.5 0.6 2.5e-06 27.5 0.6 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG36106.1 - 6.8e-06 25.7 0.0 8.8e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Ribosomal_S11 PF00411.19 OAG36106.1 - 0.1 13.0 1.0 0.27 11.6 0.3 1.9 2 0 0 2 2 2 0 Ribosomal protein S11 adh_short_C2 PF13561.6 OAG36107.1 - 3.4e-61 206.8 0.0 4.6e-61 206.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG36107.1 - 2e-41 141.6 0.0 2.8e-41 141.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG36107.1 - 4.7e-10 39.7 0.1 9.2e-10 38.7 0.1 1.4 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 OAG36107.1 - 1.1e-05 24.8 0.0 2.8e-05 23.4 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 OAG36107.1 - 0.0019 17.7 0.0 0.0028 17.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 OAG36107.1 - 0.024 13.7 0.1 0.04 13.0 0.1 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain 3Beta_HSD PF01073.19 OAG36107.1 - 0.039 13.0 0.0 0.052 12.6 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_25 PF13649.6 OAG36107.1 - 0.12 13.1 0.1 0.25 12.1 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain Sacchrp_dh_NADP PF03435.18 OAG36107.1 - 0.12 12.6 0.1 0.2 11.9 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain FAD_binding_1 PF00667.20 OAG36108.1 - 7e-57 192.5 0.0 1.1e-56 192.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 OAG36108.1 - 6.9e-32 110.6 0.3 1.6e-31 109.4 0.3 1.7 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 OAG36108.1 - 1.2e-21 77.4 0.0 7.3e-21 74.9 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain p450 PF00067.22 OAG36109.1 - 3.4e-53 181.0 0.0 4.4e-53 180.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 SnoaL_3 PF13474.6 OAG36110.1 - 2.6e-06 27.7 0.0 3.6e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 OAG36110.1 - 0.017 15.5 0.0 0.025 15.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) SnoaL_4 PF13577.6 OAG36110.1 - 0.15 12.2 0.0 0.17 12.0 0.0 1.2 1 0 0 1 1 1 0 SnoaL-like domain EthD PF07110.11 OAG36111.1 - 5.3e-16 59.6 0.1 7.8e-16 59.0 0.1 1.2 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 OAG36111.1 - 1.3e-07 32.0 0.0 1.8e-07 31.6 0.0 1.1 1 0 0 1 1 1 1 Methylmuconolactone methyl-isomerase Aldo_ket_red PF00248.21 OAG36112.1 - 1.3e-66 224.8 0.0 1.6e-66 224.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family p450 PF00067.22 OAG36113.1 - 9.2e-65 219.2 0.0 1.2e-64 218.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 adh_short_C2 PF13561.6 OAG36113.1 - 8e-59 199.0 0.0 1.1e-58 198.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG36113.1 - 8.8e-46 155.8 0.2 1.3e-45 155.2 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG36113.1 - 8e-07 29.1 0.1 1.3e-06 28.5 0.1 1.2 1 0 0 1 1 1 1 KR domain Sugar_tr PF00083.24 OAG36114.1 - 2.3e-82 277.2 25.0 2.7e-82 277.0 25.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG36114.1 - 5.3e-34 117.7 42.8 8.6e-24 84.1 16.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 OAG36114.1 - 0.00033 20.1 18.7 0.0032 16.8 3.9 2.2 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB DUF4017 PF13209.6 OAG36114.1 - 8.6 6.4 13.7 1.6 8.7 0.2 3.7 2 1 1 3 3 3 0 Protein of unknown function (DUF4017) Fungal_trans PF04082.18 OAG36115.1 - 8.3e-14 51.2 0.3 1.3e-13 50.6 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain AAA_18 PF13238.6 OAG36115.1 - 0.17 12.4 0.0 5.6 7.5 0.0 2.4 2 1 0 2 2 2 0 AAA domain FAD_binding_3 PF01494.19 OAG36116.1 - 5.2e-82 275.9 0.0 6.3e-82 275.6 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 OAG36116.1 - 0.0074 15.6 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG36116.1 - 0.03 14.5 0.5 0.095 12.9 0.5 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 OAG36116.1 - 0.2 10.6 0.1 0.33 9.9 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Pil1 PF13805.6 OAG36117.1 - 4.1e-101 337.9 8.4 5.1e-101 337.6 8.4 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 CHAD PF05235.14 OAG36117.1 - 0.011 15.8 0.9 0.017 15.1 0.9 1.4 1 0 0 1 1 1 0 CHAD domain p450 PF00067.22 OAG36118.1 - 4.2e-49 167.5 0.0 1.6e-34 119.5 0.0 2.8 2 2 0 2 2 2 2 Cytochrome P450 MukB_hinge PF16330.5 OAG36118.1 - 0.14 11.9 0.1 0.34 10.6 0.0 1.6 2 0 0 2 2 2 0 MukB hinge domain Menin PF05053.13 OAG36119.1 - 3.1 6.0 6.6 4.5 5.5 6.6 1.3 1 0 0 1 1 1 0 Menin APG9 PF04109.16 OAG36120.1 - 2.7e-197 656.6 13.6 3.1e-197 656.3 13.6 1.0 1 0 0 1 1 1 1 Autophagy protein Apg9 Glyco_hydro_47 PF01532.20 OAG36122.1 - 1.6e-176 587.7 0.2 1.9e-176 587.5 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 4HBT PF03061.22 OAG36122.1 - 0.066 13.6 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 Thioesterase superfamily DUF2013 PF09431.10 OAG36123.1 - 1.9e-49 167.3 0.2 3.3e-49 166.6 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2013) SspO PF08175.12 OAG36123.1 - 0.59 10.6 5.4 0.4 11.2 0.1 2.6 2 0 0 2 2 2 0 Small acid-soluble spore protein O family Glyco_hydro_17 PF00332.18 OAG36124.1 - 1.3e-06 28.2 1.6 3.3e-06 26.9 1.3 1.7 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 AAA PF00004.29 OAG36125.1 - 2.6e-37 128.2 0.0 4.6e-37 127.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OAG36125.1 - 2.8e-09 36.7 0.0 7.4e-09 35.3 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain Vps4_C PF09336.10 OAG36125.1 - 2.5e-08 33.8 0.0 1.9e-07 31.0 0.0 2.6 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_22 PF13401.6 OAG36125.1 - 3.3e-05 24.2 1.6 0.0005 20.4 0.1 2.8 2 1 1 3 3 3 1 AAA domain AAA_2 PF07724.14 OAG36125.1 - 4e-05 23.8 0.0 7.1e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 OAG36125.1 - 6.8e-05 22.7 0.0 0.00013 21.8 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 OAG36125.1 - 0.00049 20.1 0.0 0.0011 18.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OAG36125.1 - 0.00087 19.7 2.7 0.0024 18.3 0.6 3.0 3 1 0 3 3 2 1 AAA ATPase domain TIP49 PF06068.13 OAG36125.1 - 0.001 18.3 0.1 0.0028 16.9 0.0 1.6 1 1 0 1 1 1 1 TIP49 P-loop domain IstB_IS21 PF01695.17 OAG36125.1 - 0.0043 16.8 0.0 0.0098 15.6 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 OAG36125.1 - 0.0048 16.3 0.1 0.0096 15.3 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 OAG36125.1 - 0.016 15.4 0.4 0.051 13.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 OAG36125.1 - 0.016 14.7 0.1 0.19 11.3 0.1 2.4 1 1 0 2 2 2 0 AAA domain AAA_14 PF13173.6 OAG36125.1 - 0.023 14.7 0.0 0.051 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 OAG36125.1 - 0.035 13.8 0.0 0.12 12.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 OAG36125.1 - 0.038 13.2 0.0 0.064 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_18 PF13238.6 OAG36125.1 - 0.092 13.3 0.0 0.26 11.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 OAG36125.1 - 0.1 12.1 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 OAG36125.1 - 0.13 12.2 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Sigma54_activat PF00158.26 OAG36125.1 - 0.14 11.8 0.0 0.78 9.4 0.0 2.1 1 1 1 2 2 2 0 Sigma-54 interaction domain TniB PF05621.11 OAG36125.1 - 0.18 11.2 0.0 5.7 6.3 0.0 2.4 1 1 1 2 2 2 0 Bacterial TniB protein Mito_carr PF00153.27 OAG36126.1 - 1.5e-65 217.1 4.4 3e-23 81.5 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein IBR PF01485.21 OAG36127.1 - 1.8e-19 69.7 42.0 1.1e-09 38.3 2.4 4.6 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 OAG36127.1 - 0.00024 20.9 4.1 0.00024 20.9 4.1 4.6 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAG36127.1 - 0.00093 19.5 5.0 0.00093 19.5 5.0 4.1 2 1 1 3 3 3 1 Ring finger domain zf-RING_5 PF14634.6 OAG36127.1 - 0.001 19.0 6.9 0.001 19.0 6.9 3.8 2 1 1 3 3 3 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 OAG36127.1 - 0.0031 17.3 4.3 0.0031 17.3 4.3 5.0 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAG36127.1 - 0.007 16.4 2.8 0.007 16.4 2.8 3.9 3 1 0 3 3 3 1 RING-type zinc-finger Blt1_C PF17183.4 OAG36127.1 - 0.088 12.4 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Get5 carboxyl domain W2 PF02020.18 OAG36128.1 - 9.1e-18 64.2 2.6 2.3e-17 62.9 2.6 1.7 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.24 OAG36128.1 - 2.8e-10 39.5 13.2 0.0012 18.5 1.1 4.4 1 1 4 5 5 5 5 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.23 OAG36128.1 - 4.6e-06 26.4 0.0 8.6e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 OAG36128.1 - 0.00088 19.7 0.0 0.0019 18.6 0.0 1.5 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 OAG36128.1 - 0.0042 16.8 13.8 0.01 15.6 2.7 3.7 2 1 1 3 3 3 2 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 OAG36128.1 - 0.075 11.2 1.2 0.12 10.5 1.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) CRAL_TRIO PF00650.20 OAG36129.1 - 1.5e-39 135.2 0.0 2.6e-39 134.5 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 OAG36129.1 - 5e-08 33.0 0.2 1.1e-07 31.9 0.2 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 OAG36129.1 - 0.00038 20.6 0.0 0.00083 19.5 0.0 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DUF3879 PF12995.7 OAG36129.1 - 0.13 11.9 1.5 0.36 10.5 1.5 1.7 1 1 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3879) Mis14 PF08641.12 OAG36130.1 - 1.6e-15 57.6 0.0 3.6e-15 56.5 0.0 1.6 1 0 0 1 1 1 1 Kinetochore protein Mis14 like ubiquitin PF00240.23 OAG36131.1 - 8.4e-34 115.2 0.6 1.5e-33 114.4 0.6 1.4 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.19 OAG36131.1 - 9.1e-26 89.8 3.3 9.1e-26 89.8 3.3 2.0 2 0 0 2 2 2 1 Ribosomal protein S27a Rad60-SLD PF11976.8 OAG36131.1 - 3.9e-16 58.6 0.7 7.2e-16 57.8 0.7 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 OAG36131.1 - 2.9e-05 24.4 0.4 0.00013 22.3 0.1 2.1 2 1 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 OAG36131.1 - 0.0007 19.7 0.8 0.0016 18.5 0.8 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 OAG36131.1 - 0.0046 17.3 1.0 0.0078 16.6 0.1 1.7 1 1 1 2 2 2 1 Ubiquitin-like domain TBK1_ULD PF18396.1 OAG36131.1 - 0.0054 16.6 0.0 0.0082 16.1 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain DUF2407 PF10302.9 OAG36131.1 - 0.012 16.1 0.9 0.018 15.6 0.9 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 OAG36131.1 - 0.02 14.9 1.0 5.9 7.0 0.2 2.4 2 0 0 2 2 2 0 Ubiquitin-like domain zf-C2H2 PF00096.26 OAG36132.1 - 2.4e-08 34.0 20.3 0.0015 18.9 0.4 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OAG36132.1 - 4.3e-07 30.1 13.0 0.0047 17.3 0.3 3.7 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 OAG36132.1 - 4.7e-05 23.9 18.0 0.32 12.0 5.9 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger Bunya_G2 PF03563.13 OAG36132.1 - 0.44 9.8 3.5 0.69 9.1 3.5 1.2 1 0 0 1 1 1 0 Bunyavirus glycoprotein G2 zf-C2H2_11 PF16622.5 OAG36132.1 - 0.78 9.5 10.9 1.6 8.6 3.4 2.5 2 0 0 2 2 2 0 zinc-finger C2H2-type Transthyretin PF00576.21 OAG36134.1 - 1.3e-33 116.0 0.0 1.5e-33 115.8 0.0 1.0 1 0 0 1 1 1 1 HIUase/Transthyretin family Acetyltransf_CG PF14542.6 OAG36135.1 - 0.052 13.7 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_1 PF00583.25 OAG36135.1 - 0.099 12.9 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family adh_short PF00106.25 OAG36136.1 - 0.00044 19.8 0.0 0.00078 18.9 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase RRM_1 PF00076.22 OAG36137.1 - 2.3e-54 181.1 0.0 1.7e-17 63.0 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OAG36137.1 - 6.7e-06 25.7 0.0 0.066 12.8 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 OAG36137.1 - 1.2e-05 25.3 0.0 0.6 10.2 0.0 4.1 4 1 0 4 4 4 2 Limkain b1 RRM_3 PF08777.11 OAG36137.1 - 0.00012 22.0 0.0 0.57 10.2 0.0 3.6 3 1 1 4 4 4 2 RNA binding motif RRM_Rrp7 PF17799.1 OAG36137.1 - 0.0024 17.7 0.0 2.9 7.7 0.0 3.1 3 0 0 3 3 3 1 Rrp7 RRM-like N-terminal domain ATP-grasp_2 PF08442.10 OAG36137.1 - 0.0079 15.8 0.0 1.6 8.2 0.0 3.3 4 0 0 4 4 4 1 ATP-grasp domain DUF3343 PF11823.8 OAG36137.1 - 0.02 14.3 0.0 0.049 13.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3343) PknH_C PF14032.6 OAG36137.1 - 0.089 12.6 0.0 34 4.2 0.0 3.0 3 0 0 3 3 3 0 PknH-like extracellular domain SPOR PF05036.13 OAG36137.1 - 0.11 12.9 0.1 20 5.7 0.0 3.6 4 0 0 4 4 4 0 Sporulation related domain RRM_occluded PF16842.5 OAG36137.1 - 0.13 12.2 0.0 23 4.9 0.0 3.1 3 0 0 3 3 3 0 Occluded RNA-recognition motif p450 PF00067.22 OAG36138.1 - 1.3e-41 142.9 0.0 1.5e-41 142.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 OAG36139.1 - 1.8e-25 89.6 35.0 1.8e-25 89.6 35.0 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Amidase PF01425.21 OAG36140.1 - 2.2e-96 323.6 0.0 2.7e-96 323.3 0.0 1.1 1 0 0 1 1 1 1 Amidase Fungal_trans PF04082.18 OAG36141.1 - 1.7e-15 56.8 0.1 2.7e-15 56.1 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG36141.1 - 1.4e-05 25.1 11.5 2.8e-05 24.1 11.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain EthD PF07110.11 OAG36142.1 - 2.4e-08 35.0 0.2 3e-08 34.7 0.2 1.1 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 OAG36142.1 - 1.8e-05 25.2 0.3 2.2e-05 24.9 0.3 1.1 1 0 0 1 1 1 1 Methylmuconolactone methyl-isomerase FmdE PF02663.14 OAG36142.1 - 0.017 15.1 0.0 0.027 14.5 0.0 1.4 1 1 0 1 1 1 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon COQ9 PF08511.11 OAG36143.1 - 6.9e-32 109.1 0.8 1.1e-31 108.4 0.3 1.6 2 0 0 2 2 2 1 COQ9 HSBP1 PF06825.12 OAG36144.1 - 0.041 13.8 0.0 0.42 10.5 0.0 2.5 2 0 0 2 2 2 0 Heat shock factor binding protein 1 YjbH PF06082.11 OAG36144.1 - 0.083 11.7 1.7 0.11 11.2 1.7 1.2 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH DUF2090 PF09863.9 OAG36144.1 - 0.096 11.7 0.0 0.21 10.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2090) BBP1_C PF15272.6 OAG36144.1 - 0.31 10.8 3.7 1.3 8.9 0.3 2.7 2 1 0 3 3 3 0 Spindle pole body component BBP1, C-terminal Bromodomain PF00439.25 OAG36145.1 - 8.3e-38 128.3 3.7 1.4e-18 66.7 0.3 2.6 2 0 0 2 2 2 2 Bromodomain BAH PF01426.18 OAG36145.1 - 2.2e-18 66.3 1.5 7.3e-18 64.6 1.5 2.0 1 0 0 1 1 1 1 BAH domain HTH_32 PF13565.6 OAG36145.1 - 1.9 9.2 9.5 38 5.0 7.3 3.5 2 1 0 2 2 2 0 Homeodomain-like domain OTU PF02338.19 OAG36146.1 - 3.7e-08 33.9 0.0 7.5e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 OTU-like cysteine protease UBX PF00789.20 OAG36146.1 - 0.016 15.4 0.0 0.034 14.3 0.0 1.6 1 0 0 1 1 1 0 UBX domain COG6 PF06419.11 OAG36147.1 - 8e-158 526.5 0.0 9.4e-158 526.2 0.0 1.1 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 Abhydrolase_3 PF07859.13 OAG36147.1 - 9.4e-48 162.9 0.0 1.6e-47 162.1 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 OAG36147.1 - 2.2e-10 40.0 0.0 6.8e-10 38.4 0.0 1.6 1 1 0 1 1 1 1 Carboxylesterase family Say1_Mug180 PF10340.9 OAG36147.1 - 0.0045 15.9 0.0 0.008 15.1 0.0 1.3 1 0 0 1 1 1 1 Steryl acetyl hydrolase DUF4570 PF15134.6 OAG36147.1 - 0.02 14.9 0.6 0.27 11.3 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4570) Peptidase_S9 PF00326.21 OAG36147.1 - 0.094 12.2 0.0 0.24 10.8 0.0 1.7 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 OAG36147.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Redoxin PF08534.10 OAG36148.1 - 1.4e-28 99.5 0.0 1.7e-28 99.2 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 OAG36148.1 - 2.4e-09 37.2 0.0 3e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family HSF_DNA-bind PF00447.17 OAG36149.1 - 7.3e-32 109.9 2.6 1.7e-31 108.7 2.6 1.7 1 0 0 1 1 1 1 HSF-type DNA-binding Response_reg PF00072.24 OAG36149.1 - 7.2e-24 84.1 0.1 1.7e-23 82.9 0.1 1.7 1 0 0 1 1 1 1 Response regulator receiver domain Ets PF00178.22 OAG36149.1 - 0.094 13.2 0.1 0.22 12.0 0.1 1.6 1 0 0 1 1 1 0 Ets-domain BolA PF01722.18 OAG36150.1 - 6.5e-16 58.4 0.0 9.9e-16 57.8 0.0 1.3 1 0 0 1 1 1 1 BolA-like protein NIF3 PF01784.18 OAG36151.1 - 6.7e-55 186.4 0.0 1e-54 185.8 0.0 1.2 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) Asp PF00026.23 OAG36152.1 - 5e-58 197.0 1.4 5.9e-58 196.7 1.4 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OAG36152.1 - 1.1e-13 51.8 2.3 8.1e-08 32.7 0.1 2.5 2 0 0 2 2 2 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 OAG36152.1 - 0.012 16.2 1.5 4.9 7.9 0.1 3.4 3 0 0 3 3 3 0 Aspartyl protease IBN_N PF03810.19 OAG36153.1 - 4.2e-08 33.0 0.0 3.2e-07 30.1 0.0 2.7 1 0 0 1 1 1 1 Importin-beta N-terminal domain Xpo1 PF08389.12 OAG36153.1 - 2e-05 24.7 1.7 0.05 13.7 0.0 5.4 6 0 0 6 6 6 1 Exportin 1-like protein HEAT_EZ PF13513.6 OAG36153.1 - 4.5 7.9 7.5 6.1 7.5 0.3 4.3 4 0 0 4 4 4 0 HEAT-like repeat PX PF00787.24 OAG36154.1 - 1.1e-16 60.9 0.1 2.5e-16 59.7 0.1 1.6 1 0 0 1 1 1 1 PX domain Prefoldin_3 PF13758.6 OAG36154.1 - 0.063 13.3 0.2 0.063 13.3 0.2 2.4 3 1 0 3 3 3 0 Prefoldin subunit Zwint PF15556.6 OAG36155.1 - 0.015 14.8 0.3 0.015 14.8 0.3 1.7 2 0 0 2 2 2 0 ZW10 interactor FAD-SLDH PF12318.8 OAG36155.1 - 0.058 13.5 1.9 0.16 12.0 0.5 2.0 2 0 0 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase FCP1_C PF09309.10 OAG36155.1 - 0.066 13.1 0.3 0.066 13.1 0.3 1.9 2 1 0 1 1 1 0 FCP1, C-terminal JAB PF01398.21 OAG36156.1 - 1.8e-29 102.1 0.0 3.6e-29 101.2 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease CSN5_C PF18323.1 OAG36156.1 - 3.3e-22 79.2 0.0 6.7e-22 78.2 0.0 1.5 1 0 0 1 1 1 1 Cop9 signalosome subunit 5 C-terminal domain Prok-JAB PF14464.6 OAG36156.1 - 7.4e-06 25.7 0.3 4.2e-05 23.3 0.0 2.3 3 0 0 3 3 3 1 Prokaryotic homologs of the JAB domain MAP65_ASE1 PF03999.12 OAG36157.1 - 8.2e-78 262.6 5.8 8.2e-78 262.6 5.8 2.5 2 1 0 2 2 2 1 Microtubule associated protein (MAP65/ASE1 family) VGPC1_C PF16799.5 OAG36157.1 - 0.045 13.7 1.1 10 6.2 0.1 2.8 2 0 0 2 2 2 0 C-terminal membrane-localisation domain of ion-channel, VCN1 DUF1140 PF06600.11 OAG36157.1 - 0.074 13.5 0.1 0.31 11.5 0.1 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1140) Spectrin PF00435.21 OAG36157.1 - 0.6 10.6 12.8 0.63 10.5 1.2 3.9 3 1 0 3 3 3 0 Spectrin repeat Mannosyl_trans3 PF11051.8 OAG36158.1 - 2.4e-59 200.9 0.1 1.1e-36 126.7 0.0 2.2 1 1 1 2 2 2 2 Mannosyltransferase putative Fungal_trans_2 PF11951.8 OAG36159.1 - 0.00011 21.1 0.4 0.00066 18.6 0.3 2.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain NAD_binding_2 PF03446.15 OAG36160.1 - 5.4e-39 133.9 0.0 9.6e-39 133.1 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 OAG36160.1 - 7.1e-25 87.6 0.0 1e-24 87.1 0.0 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase GFO_IDH_MocA PF01408.22 OAG36160.1 - 0.0097 16.7 0.0 0.018 15.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.17 OAG36160.1 - 0.014 16.0 0.0 0.03 14.9 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 OAG36160.1 - 0.035 13.5 0.0 0.08 12.3 0.0 1.6 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UIM PF02809.20 OAG36161.1 - 0.58 10.2 19.8 0.03 14.2 3.1 3.5 3 0 0 3 3 3 0 Ubiquitin interaction motif Mre11_DNA_bind PF04152.14 OAG36163.1 - 1.8e-49 168.3 2.6 1.8e-49 168.3 2.6 2.2 3 0 0 3 3 3 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 OAG36163.1 - 4.6e-14 53.4 4.6 7.9e-14 52.6 4.6 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OAG36163.1 - 0.00057 20.1 0.6 0.0045 17.2 0.6 2.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain MRP-S28 PF10213.9 OAG36163.1 - 0.089 13.2 1.0 5.7 7.4 0.0 2.6 2 0 0 2 2 2 0 Mitochondrial ribosomal subunit protein Smg4_UPF3 PF03467.15 OAG36164.1 - 3.5e-39 134.6 0.0 3.5e-39 134.6 0.0 2.8 1 1 1 2 2 2 1 Smg-4/UPF3 family RRM_1 PF00076.22 OAG36164.1 - 1.5e-09 37.5 0.5 5e-08 32.7 0.0 3.0 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Thioredoxin_4 PF13462.6 OAG36164.1 - 0.0091 16.2 1.8 0.022 14.9 1.8 1.6 1 0 0 1 1 1 1 Thioredoxin Nup35_RRM_2 PF14605.6 OAG36164.1 - 0.12 12.4 0.1 0.3 11.1 0.0 1.7 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Metallophos PF00149.28 OAG36165.1 - 1.5e-33 117.0 0.0 3.3e-29 102.8 0.0 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 OAG36165.1 - 0.12 11.9 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain ABC_tran PF00005.27 OAG36166.1 - 8.7e-23 81.4 0.0 9e-12 45.7 0.0 2.9 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 OAG36166.1 - 6e-08 32.8 3.1 0.0079 16.0 0.0 2.9 2 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 OAG36166.1 - 1.9e-05 24.8 0.0 0.0098 16.1 0.0 2.6 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.6 OAG36166.1 - 0.026 14.8 0.0 0.31 11.3 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_29 PF13555.6 OAG36166.1 - 0.032 14.0 0.1 0.067 12.9 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 OAG36166.1 - 0.048 14.0 0.4 0.37 11.1 0.1 2.5 3 1 0 3 3 3 0 AAA ATPase domain AAA_23 PF13476.6 OAG36166.1 - 0.067 13.7 0.2 0.13 12.8 0.2 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 OAG36166.1 - 0.13 12.1 0.0 0.4 10.6 0.0 1.8 2 0 0 2 2 2 0 NACHT domain ADH_N PF08240.12 OAG36168.1 - 3.5e-26 91.2 4.4 6.1e-26 90.4 4.4 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG36168.1 - 2.6e-15 56.6 0.0 7.3e-15 55.1 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 OAG36168.1 - 5.1e-06 25.9 0.0 7.8e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 OAG36168.1 - 0.0011 18.4 0.0 0.0017 17.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 OAG36168.1 - 0.014 15.3 0.1 0.038 13.9 0.0 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 OAG36168.1 - 0.062 13.7 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding DUF726 PF05277.12 OAG36168.1 - 0.13 11.2 0.3 0.2 10.6 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF726) UvdE PF03851.14 OAG36169.1 - 4e-110 367.4 0.0 5.2e-110 367.0 0.0 1.1 1 0 0 1 1 1 1 UV-endonuclease UvdE PBP1_TM PF14812.6 OAG36169.1 - 7.3 7.0 12.4 1.3 9.5 3.5 3.7 3 1 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal F-box-like PF12937.7 OAG36170.1 - 0.066 13.1 0.3 0.16 11.9 0.3 1.7 1 0 0 1 1 1 0 F-box-like SH3_9 PF14604.6 OAG36172.1 - 2e-05 24.4 0.5 5e-05 23.1 0.2 1.8 2 0 0 2 2 2 1 Variant SH3 domain Adeno_E3_CR2 PF02439.15 OAG36172.1 - 2.9e-05 23.7 2.0 5.2e-05 22.9 2.0 1.3 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 SH3_1 PF00018.28 OAG36172.1 - 0.00027 20.5 1.2 0.00032 20.2 0.1 1.7 2 0 0 2 2 2 1 SH3 domain EphA2_TM PF14575.6 OAG36172.1 - 0.00045 21.1 0.0 0.00089 20.1 0.0 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain DUF4690 PF15756.5 OAG36172.1 - 0.00094 19.7 0.1 0.0026 18.3 0.1 1.7 1 0 0 1 1 1 1 Small Novel Rich in Cartilage Insulin_TMD PF17870.1 OAG36172.1 - 0.033 14.2 0.5 0.063 13.4 0.5 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Syndecan PF01034.20 OAG36172.1 - 0.13 12.2 0.7 0.25 11.3 0.7 1.3 1 0 0 1 1 1 0 Syndecan domain KCT2 PF17818.1 OAG36173.1 - 4.8 7.3 5.3 20 5.2 4.1 2.7 2 0 0 2 2 2 0 Keratinocyte-associated gene product LapA_dom PF06305.11 OAG36175.1 - 5.9 6.8 5.4 3 7.7 0.2 2.6 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain F1F0-ATPsyn_F PF10791.9 OAG36176.1 - 1.6e-39 134.3 0.2 1.8e-39 134.1 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi WRW PF10206.9 OAG36176.1 - 0.0096 16.3 0.0 0.011 16.0 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial F1F0-ATP synthase, subunit f PAPA-1 PF04795.12 OAG36177.1 - 0.013 16.3 5.8 0.013 16.3 5.8 3.0 2 0 0 2 2 2 0 PAPA-1-like conserved region Cas_Csy4 PF09618.10 OAG36177.1 - 0.55 10.4 2.8 0.35 11.0 0.3 1.8 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Csy4) EF-hand_1 PF00036.32 OAG36178.1 - 2.9e-36 120.3 9.9 4e-09 35.4 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 OAG36178.1 - 7.5e-29 100.0 5.2 2.6e-15 56.6 0.5 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OAG36178.1 - 7.5e-28 94.1 5.6 1.3e-08 34.1 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 OAG36178.1 - 1.4e-25 88.8 10.4 1.5e-12 47.2 0.4 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 OAG36178.1 - 2.2e-24 83.8 13.8 1e-07 31.1 0.0 5.0 5 0 0 5 5 5 4 EF hand EF-hand_9 PF14658.6 OAG36178.1 - 4.5e-13 49.3 0.2 1.9e-08 34.5 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 OAG36178.1 - 1.3e-06 28.3 1.8 5e-05 23.2 0.2 2.1 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_11 PF08976.11 OAG36178.1 - 1.4e-06 29.1 0.1 0.057 14.3 0.0 2.1 1 1 1 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 OAG36178.1 - 1.1e-05 25.6 0.5 0.11 12.9 0.0 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.13 OAG36178.1 - 1.3e-05 25.1 0.1 0.083 12.9 0.0 2.4 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0154) EF-hand_14 PF17959.1 OAG36178.1 - 4.6e-05 23.7 0.2 0.43 11.0 0.0 2.4 2 1 0 2 2 2 2 EF-hand domain RNA_pol_Rpb4 PF03874.16 OAG36178.1 - 0.002 18.5 1.2 0.73 10.2 0.4 2.5 2 0 0 2 2 2 1 RNA polymerase Rpb4 Toprim_2 PF13155.6 OAG36178.1 - 0.0025 18.2 0.8 0.55 10.7 0.0 2.3 1 1 1 2 2 2 1 Toprim-like DUF3349 PF11829.8 OAG36178.1 - 0.0032 18.2 0.0 1.3 9.8 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3349) FGAR-AT_linker PF18072.1 OAG36178.1 - 0.0033 17.9 0.0 0.58 10.7 0.0 2.6 2 1 0 2 2 2 1 Formylglycinamide ribonucleotide amidotransferase linker domain DUF4497 PF14924.6 OAG36178.1 - 0.0093 16.4 0.0 1.7 9.1 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF4497) SurA_N_2 PF13623.6 OAG36178.1 - 0.01 15.7 1.1 1 9.2 0.2 2.3 1 1 1 2 2 2 1 SurA N-terminal domain dCache_2 PF08269.11 OAG36178.1 - 0.017 14.3 0.0 0.025 13.8 0.0 1.4 1 1 0 1 1 1 0 Cache domain Maf PF02545.14 OAG36178.1 - 0.025 14.4 0.2 0.72 9.7 0.0 2.2 1 1 0 2 2 2 0 Maf-like protein YqeY PF09424.10 OAG36178.1 - 0.026 14.6 0.4 0.36 10.9 0.2 2.1 1 1 1 2 2 2 0 Yqey-like protein DUF1296 PF06972.11 OAG36178.1 - 0.037 14.2 2.1 0.3 11.3 0.3 2.6 3 0 0 3 3 2 0 Protein of unknown function (DUF1296) DUF4539 PF15072.6 OAG36178.1 - 0.04 14.0 0.7 6.3 6.9 0.1 2.9 2 1 0 3 3 3 0 Domain of unknown function (DUF4539) Cytochrome_CBB3 PF13442.6 OAG36178.1 - 0.044 14.1 0.1 19 5.7 0.0 3.0 3 0 0 3 3 3 0 Cytochrome C oxidase, cbb3-type, subunit III DUF1456 PF07308.13 OAG36178.1 - 0.056 13.8 0.8 3.2 8.2 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1456) Dockerin_1 PF00404.18 OAG36178.1 - 0.072 13.3 2.2 3.5 7.9 0.0 2.7 2 1 1 3 3 3 0 Dockerin type I domain MotA_activ PF09114.10 OAG36178.1 - 0.082 13.0 0.1 13 6.0 0.0 2.2 1 1 1 2 2 2 0 Transcription factor MotA, activation domain Syntaxin PF00804.25 OAG36178.1 - 0.086 12.5 1.3 0.6 9.7 0.3 2.1 1 1 0 2 2 2 0 Syntaxin DNA_pol3_beta PF00712.19 OAG36178.1 - 0.11 12.6 0.4 1.9 8.7 0.1 2.1 1 1 1 2 2 2 0 DNA polymerase III beta subunit, N-terminal domain DUF1840 PF08895.11 OAG36178.1 - 0.14 12.5 0.5 7.3 7.0 0.2 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF1840) Glycos_trans_3N PF02885.17 OAG36178.1 - 0.21 11.5 1.9 22 5.0 0.1 3.6 3 2 2 5 5 4 0 Glycosyl transferase family, helical bundle domain PB1 PF00564.24 OAG36178.1 - 0.34 10.9 3.2 36 4.4 0.1 3.4 2 1 1 3 3 3 0 PB1 domain Mst1_SARAH PF11629.8 OAG36178.1 - 0.81 9.8 3.0 1.9 8.7 0.4 2.6 2 1 0 2 2 2 0 C terminal SARAH domain of Mst1 PNP_phzG_C PF10590.9 OAG36179.1 - 2.5e-21 75.5 1.5 6.3e-21 74.2 0.9 2.0 2 0 0 2 2 2 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Putative_PNPOx PF01243.20 OAG36179.1 - 8e-17 61.2 0.0 1.3e-16 60.6 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxase_2 PF12766.7 OAG36179.1 - 0.0047 17.5 0.0 0.0098 16.5 0.0 1.6 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Ras PF00071.22 OAG36180.1 - 5.5e-52 175.6 0.1 1e-51 174.8 0.1 1.4 1 0 0 1 1 1 1 Ras family PPR_2 PF13041.6 OAG36180.1 - 3.7e-47 158.3 2.8 8.8e-11 41.8 0.0 11.9 10 2 3 13 13 13 8 PPR repeat family Roc PF08477.13 OAG36180.1 - 4.7e-32 110.7 0.1 1e-31 109.6 0.1 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase PPR_3 PF13812.6 OAG36180.1 - 2.5e-31 107.5 4.0 0.001 19.1 0.0 12.5 8 3 3 12 12 12 5 Pentatricopeptide repeat domain PPR PF01535.20 OAG36180.1 - 8.6e-24 82.1 12.2 0.0016 18.6 0.1 13.9 15 1 0 15 15 13 4 PPR repeat PPR_long PF17177.4 OAG36180.1 - 6.1e-17 61.7 8.3 4.5e-07 29.4 0.0 5.8 3 1 2 5 5 5 4 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 OAG36180.1 - 1.7e-16 59.6 0.0 1.2e-05 24.9 0.0 8.1 9 0 0 9 9 9 2 PPR repeat Arf PF00025.21 OAG36180.1 - 1.5e-13 50.6 0.1 3e-13 49.6 0.1 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OAG36180.1 - 7e-05 22.5 0.0 0.00024 20.7 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain RPM2 PF08579.11 OAG36180.1 - 0.00027 21.3 0.5 0.34 11.3 0.0 4.4 5 0 0 5 5 3 1 Mitochondrial ribonuclease P subunit (RPM2) BTAD PF03704.17 OAG36180.1 - 0.0028 18.1 1.8 0.26 11.7 0.2 4.0 2 1 0 3 3 3 1 Bacterial transcriptional activator domain MMR_HSR1 PF01926.23 OAG36180.1 - 0.0032 17.5 0.0 0.0094 16.0 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 OAG36180.1 - 0.0046 16.4 0.0 0.015 14.8 0.0 1.8 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit DEP PF00610.21 OAG36180.1 - 0.042 13.9 0.1 14 5.8 0.0 3.7 4 0 0 4 4 4 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) TPR_14 PF13428.6 OAG36180.1 - 0.062 14.1 10.0 4.6 8.3 0.2 7.5 7 2 1 8 8 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 OAG36180.1 - 0.34 11.1 6.0 18 5.7 0.0 5.1 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 OAG36180.1 - 1.4 9.5 0.0 1.4 9.5 0.0 5.5 6 0 0 6 6 4 0 Tetratricopeptide repeat Ribosomal_S19 PF00203.21 OAG36181.1 - 3.6e-22 78.0 0.1 4.6e-22 77.7 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 TFIID_30kDa PF03540.13 OAG36182.1 - 7.2e-23 80.3 0.1 1.2e-22 79.6 0.1 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit TRF PF08558.10 OAG36183.1 - 1.3e-44 152.6 0.0 4e-44 151.0 0.0 1.7 2 0 0 2 2 2 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.31 OAG36183.1 - 0.0005 20.2 0.0 0.0012 19.0 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain HTH_32 PF13565.6 OAG36183.1 - 2.8 8.6 5.5 26 5.5 0.2 3.9 4 0 0 4 4 4 0 Homeodomain-like domain His_Phos_2 PF00328.22 OAG36184.1 - 1.7e-10 40.8 0.0 5.7e-10 39.1 0.0 1.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF3606 PF12244.8 OAG36185.1 - 0.11 12.4 0.9 4 7.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3606) Pkinase PF00069.25 OAG36186.1 - 2.2e-76 256.7 0.0 4.6e-76 255.7 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG36186.1 - 2.1e-31 109.1 0.0 9.6e-23 80.8 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 OAG36186.1 - 2.9e-08 33.4 0.1 0.043 13.1 0.0 3.1 3 0 0 3 3 3 3 Kinase-like Pkinase_fungal PF17667.1 OAG36186.1 - 0.0079 15.0 0.0 0.013 14.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OAG36186.1 - 0.023 14.1 0.0 0.039 13.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OAG36186.1 - 0.16 11.9 0.0 2.3 8.1 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family GDPD PF03009.17 OAG36187.1 - 1e-75 254.9 0.0 3.2e-75 253.2 0.0 1.9 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.7 OAG36187.1 - 4.7e-31 107.2 0.0 6.6e-19 68.3 0.0 3.9 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAG36187.1 - 4.3e-28 97.3 4.8 6.3e-12 45.8 0.1 5.9 6 0 0 6 6 6 4 Ankyrin repeats (many copies) SPX PF03105.19 OAG36187.1 - 7.1e-21 75.6 17.5 3.6e-11 43.6 0.0 4.6 3 1 2 5 5 5 3 SPX domain Ank PF00023.30 OAG36187.1 - 1.1e-18 66.8 3.4 0.0001 22.6 0.0 6.2 6 0 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.6 OAG36187.1 - 2.3e-18 64.4 9.6 9.1e-06 25.7 0.0 7.3 8 0 0 8 8 8 4 Ankyrin repeat Ank_5 PF13857.6 OAG36187.1 - 1.3e-17 63.6 0.4 6.8e-07 29.5 0.0 6.1 4 1 3 7 7 7 4 Ankyrin repeats (many copies) Dynamitin PF04912.14 OAG36187.1 - 0.076 12.3 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Dynamitin dsrm PF00035.26 OAG36188.1 - 8e-06 26.5 0.2 7.7e-05 23.3 0.3 2.2 2 0 0 2 2 2 1 Double-stranded RNA binding motif zf-RING_6 PF14835.6 OAG36189.1 - 0.19 11.6 0.0 0.32 10.9 0.0 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein AAA PF00004.29 OAG36190.1 - 5.6e-07 30.0 0.4 7.7e-07 29.6 0.4 1.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) SCAPER_N PF16501.5 OAG36190.1 - 0.067 13.2 0.0 0.18 11.9 0.0 1.7 1 0 0 1 1 1 0 S phase cyclin A-associated protein in the endoplasmic reticulum Cys_Met_Meta_PP PF01053.20 OAG36191.1 - 9.6e-32 109.9 0.0 1.3e-31 109.5 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme PCMT PF01135.19 OAG36192.1 - 1.2e-64 218.0 0.0 1.3e-64 217.8 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 OAG36192.1 - 1.4e-07 31.5 0.0 2.2e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG36192.1 - 1.4e-07 32.1 0.0 2.3e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 OAG36192.1 - 2.8e-06 27.4 0.0 4.3e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG36192.1 - 0.00014 22.4 0.0 0.00023 21.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAG36192.1 - 0.00027 20.8 0.0 0.00035 20.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OAG36192.1 - 0.0013 18.3 0.0 0.002 17.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 OAG36192.1 - 0.0026 17.1 0.0 0.0035 16.7 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 OAG36192.1 - 0.0066 17.2 0.0 0.01 16.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 OAG36192.1 - 0.024 14.0 0.0 0.032 13.6 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_24 PF13578.6 OAG36192.1 - 0.035 15.1 0.0 0.061 14.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.19 OAG36192.1 - 0.14 12.3 0.0 0.23 11.6 0.0 1.4 1 1 0 1 1 1 0 FtsJ-like methyltransferase Peptidase_M20 PF01546.28 OAG36193.1 - 4.3e-32 111.5 0.0 5.3e-32 111.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 OAG36193.1 - 1.1e-11 44.6 0.0 1.7e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 OAG36193.1 - 0.12 12.0 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M28 MRP-L20 PF12824.7 OAG36194.1 - 5.8e-49 166.4 5.9 6.8e-49 166.2 5.9 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Neugrin PF06413.11 OAG36194.1 - 0.0096 16.0 0.2 0.014 15.5 0.2 1.3 1 0 0 1 1 1 1 Neugrin adh_short PF00106.25 OAG36197.1 - 2.9e-34 118.3 0.0 3.9e-34 117.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG36197.1 - 2.3e-21 76.4 0.0 3.2e-21 76.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG36197.1 - 1.5e-09 38.0 0.1 2.5e-09 37.3 0.1 1.3 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 OAG36197.1 - 0.01 14.8 0.0 0.013 14.5 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 OAG36197.1 - 0.064 12.4 0.0 0.09 11.9 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein ICL PF00463.21 OAG36198.1 - 6.7e-296 981.8 4.3 7.6e-296 981.6 4.3 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 OAG36198.1 - 8.8e-12 45.0 0.1 5.2e-11 42.4 0.0 2.0 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase Trehalase PF01204.18 OAG36199.1 - 6.8e-183 609.1 0.0 9.6e-183 608.7 0.0 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.11 OAG36199.1 - 5.6e-15 54.7 1.1 9.5e-15 54.0 1.1 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain Aldedh PF00171.22 OAG36200.1 - 2.9e-83 279.9 0.0 3.5e-83 279.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Oxysterol_BP PF01237.18 OAG36201.1 - 3.7e-48 164.3 0.0 2e-46 158.5 0.0 2.1 1 1 0 1 1 1 1 Oxysterol-binding protein OmpH PF03938.14 OAG36202.1 - 0.0047 17.3 10.1 0.0047 17.3 10.1 1.5 2 0 0 2 2 2 1 Outer membrane protein (OmpH-like) DUF1640 PF07798.11 OAG36202.1 - 0.0082 16.2 5.2 0.015 15.3 5.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) AAA_17 PF13207.6 OAG36202.1 - 0.036 14.5 1.2 0.56 10.6 0.9 2.1 2 0 0 2 2 2 0 AAA domain ApoO PF09769.9 OAG36202.1 - 0.098 12.6 0.2 0.15 12.0 0.2 1.4 1 0 0 1 1 1 0 Apolipoprotein O PIN_4 PF13638.6 OAG36202.1 - 0.1 12.9 1.1 0.17 12.1 1.1 1.4 1 0 0 1 1 1 0 PIN domain DUF2203 PF09969.9 OAG36202.1 - 0.13 13.0 2.3 3.1 8.5 3.1 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Prominin PF05478.11 OAG36202.1 - 0.22 9.4 5.0 0.36 8.7 4.9 1.3 1 1 0 1 1 1 0 Prominin Metal_resist PF13801.6 OAG36202.1 - 0.47 10.6 14.2 1.9 8.7 14.1 2.0 1 1 0 1 1 1 0 Heavy-metal resistance YojJ PF10372.9 OAG36202.1 - 0.54 10.4 5.1 26 5.0 5.2 2.7 1 1 0 1 1 1 0 Bacterial membrane-spanning protein N-terminus CemA PF03040.14 OAG36202.1 - 0.94 9.4 3.1 1.4 8.8 3.1 1.3 1 0 0 1 1 1 0 CemA family Fungal_trans PF04082.18 OAG36203.1 - 2.1e-19 69.6 0.1 4.4e-19 68.5 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 OAG36203.1 - 0.0001 22.5 10.4 0.073 13.6 1.8 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type FOXP-CC PF16159.5 OAG36203.1 - 0.012 16.2 2.4 1.5 9.5 0.2 2.5 2 0 0 2 2 2 0 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 OAG36203.1 - 0.096 13.6 8.2 2.4 9.3 0.9 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger Cnd1_N PF12922.7 OAG36206.1 - 3.6e-60 202.6 0.6 1.1e-59 201.0 0.6 1.9 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1, N-term Cnd1 PF12717.7 OAG36206.1 - 2e-47 161.3 3.3 2e-42 145.0 0.1 3.8 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 OAG36206.1 - 1e-08 34.7 10.9 0.075 13.3 0.1 6.7 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.6 OAG36206.1 - 1.4e-08 35.0 7.9 0.00019 21.8 0.0 4.9 4 1 1 5 5 5 2 HEAT repeats Adaptin_N PF01602.20 OAG36206.1 - 2e-06 26.7 7.9 0.0076 14.9 0.4 4.2 4 1 1 5 5 5 2 Adaptin N terminal region RTP1_C1 PF10363.9 OAG36206.1 - 5.3e-06 26.6 0.0 0.0038 17.4 0.0 3.7 2 0 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 OAG36206.1 - 4.6e-05 23.8 6.4 0.055 14.0 0.1 5.8 5 0 0 5 5 5 1 HEAT-like repeat Cnd3 PF12719.7 OAG36206.1 - 0.00036 19.8 0.7 0.00036 19.8 0.7 4.1 4 1 0 4 4 4 1 Nuclear condensing complex subunits, C-term domain RIX1 PF08167.12 OAG36206.1 - 0.0039 16.9 1.2 11 5.6 0.0 4.3 5 0 0 5 5 5 2 rRNA processing/ribosome biogenesis Pkinase PF00069.25 OAG36207.1 - 2.6e-42 145.0 0.0 7.3e-39 133.7 0.0 3.1 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAG36207.1 - 2.3e-12 46.8 0.0 2.4e-07 30.3 0.0 3.3 3 0 0 3 3 3 3 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAG36207.1 - 0.0039 16.0 0.0 0.012 14.4 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 OAG36207.1 - 0.0043 17.0 0.2 0.0043 17.0 0.2 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 OAG36207.1 - 0.024 14.3 0.0 0.19 11.3 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 OAG36207.1 - 0.045 13.1 0.0 1.9 7.8 0.0 2.1 2 0 0 2 2 2 0 Kinase-like Kdo PF06293.14 OAG36207.1 - 0.058 12.8 0.0 0.19 11.1 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Hydrolase PF00702.26 OAG36208.1 - 8e-12 45.9 0.1 5.7e-09 36.6 0.1 3.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 OAG36208.1 - 5.6e-10 39.6 0.0 7.3e-06 26.2 0.0 2.7 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OAG36208.1 - 0.00019 21.4 0.0 0.00081 19.4 0.0 2.0 2 0 0 2 2 2 1 HAD-hyrolase-like HAD PF12710.7 OAG36208.1 - 0.0089 16.4 0.1 6.4 7.1 0.0 2.7 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase DAGK_prokar PF01219.19 OAG36209.1 - 0.17 11.7 0.2 0.31 10.9 0.2 1.3 1 0 0 1 1 1 0 Prokaryotic diacylglycerol kinase PALP PF00291.25 OAG36210.1 - 1.4e-58 198.7 0.1 1.5e-58 198.5 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme 3HCDH_N PF02737.18 OAG36210.1 - 0.15 11.9 0.1 0.29 11.0 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain IBR PF01485.21 OAG36211.1 - 1.3e-05 25.3 34.6 0.00013 22.2 15.4 3.7 2 2 1 3 3 3 2 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 OAG36211.1 - 0.0049 16.7 5.5 0.0049 16.7 5.5 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) DUF2158 PF09926.9 OAG36211.1 - 0.033 13.9 0.3 0.067 12.9 0.3 1.4 1 0 0 1 1 1 0 Uncharacterized small protein (DUF2158) Iso_dh PF00180.20 OAG36212.1 - 2.3e-120 401.9 0.0 4.5e-120 400.9 0.0 1.4 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase ABC_tran PF00005.27 OAG36213.1 - 1.3e-46 158.6 0.0 5.2e-25 88.6 0.0 2.9 3 0 0 3 3 2 2 ABC transporter ABC_membrane PF00664.23 OAG36213.1 - 8e-34 117.5 32.2 2e-26 93.3 5.8 2.7 3 0 0 3 3 2 2 ABC transporter transmembrane region SMC_N PF02463.19 OAG36213.1 - 7.9e-16 58.1 2.2 2.8e-05 23.7 0.0 4.2 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 OAG36213.1 - 5.3e-09 36.3 0.0 0.87 9.3 0.0 4.3 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 OAG36213.1 - 2.1e-06 27.4 0.4 0.036 13.8 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 OAG36213.1 - 1.9e-05 25.0 1.7 0.11 12.7 0.0 3.7 5 0 0 5 5 3 2 AAA domain RsgA_GTPase PF03193.16 OAG36213.1 - 4.2e-05 23.5 0.4 0.13 12.2 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA PF00004.29 OAG36213.1 - 8.8e-05 22.9 0.0 0.033 14.6 0.0 3.7 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OAG36213.1 - 9.9e-05 22.8 0.1 0.18 12.1 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain NB-ARC PF00931.22 OAG36213.1 - 0.00035 19.8 2.1 0.024 13.8 0.0 3.3 2 2 0 2 2 2 1 NB-ARC domain AAA_5 PF07728.14 OAG36213.1 - 0.00054 20.0 0.0 1.7 8.7 0.0 3.8 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 OAG36213.1 - 0.00059 19.4 0.0 0.092 12.2 0.0 2.7 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_33 PF13671.6 OAG36213.1 - 0.00069 19.8 0.1 0.066 13.4 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_23 PF13476.6 OAG36213.1 - 0.00088 19.8 0.0 0.22 12.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 OAG36213.1 - 0.0014 18.6 0.0 2.1 8.4 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase RNA_helicase PF00910.22 OAG36213.1 - 0.0048 17.3 0.1 2.4 8.6 0.0 3.1 3 0 0 3 3 3 1 RNA helicase NACHT PF05729.12 OAG36213.1 - 0.005 16.8 0.2 0.87 9.5 0.0 2.7 2 0 0 2 2 2 1 NACHT domain AAA_25 PF13481.6 OAG36213.1 - 0.0074 15.9 0.1 0.24 10.9 0.0 2.9 3 0 0 3 3 2 1 AAA domain Rad17 PF03215.15 OAG36213.1 - 0.0076 16.2 0.0 0.33 10.9 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_30 PF13604.6 OAG36213.1 - 0.0093 15.7 0.4 8.2 6.1 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.6 OAG36213.1 - 0.02 14.6 0.1 1.7 8.3 0.0 2.6 2 1 0 2 2 2 0 AAA domain Septin PF00735.18 OAG36213.1 - 0.023 14.0 0.0 2.8 7.2 0.0 2.2 2 0 0 2 2 2 0 Septin KAP_NTPase PF07693.14 OAG36213.1 - 0.025 13.8 0.0 4.6 6.4 0.0 2.2 2 0 0 2 2 2 0 KAP family P-loop domain ATPase_2 PF01637.18 OAG36213.1 - 0.029 14.3 0.1 0.24 11.3 0.0 2.4 3 0 0 3 3 2 0 ATPase domain predominantly from Archaea cobW PF02492.19 OAG36213.1 - 0.03 13.9 0.1 0.44 10.1 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ATP-synt_ab PF00006.25 OAG36213.1 - 0.031 13.9 0.0 1.9 8.1 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Roc PF08477.13 OAG36213.1 - 0.034 14.4 0.2 7.1 6.9 0.0 3.2 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase FtsK_SpoIIIE PF01580.18 OAG36213.1 - 0.052 12.9 0.1 4.1 6.7 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_15 PF13175.6 OAG36213.1 - 0.059 13.1 0.0 4.8 6.8 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain NTPase_1 PF03266.15 OAG36213.1 - 0.074 13.0 1.7 17 5.3 0.2 3.0 3 0 0 3 3 3 0 NTPase AAA_14 PF13173.6 OAG36213.1 - 0.088 12.8 0.1 0.98 9.5 0.0 2.7 4 0 0 4 4 3 0 AAA domain ATP_bind_1 PF03029.17 OAG36213.1 - 0.11 12.3 0.0 5.6 6.7 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DUF87 PF01935.17 OAG36213.1 - 0.21 11.6 0.7 3.4 7.7 0.0 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain MeaB PF03308.16 OAG36213.1 - 0.22 10.5 0.4 0.82 8.6 0.0 2.0 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF2207 PF09972.9 OAG36213.1 - 0.83 8.3 2.3 1.4 7.6 0.0 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF2985 PF11204.8 OAG36213.1 - 1.5 9.0 4.8 0.59 10.3 0.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2985) Glyco_hydro_16 PF00722.21 OAG36214.1 - 3.9e-07 29.7 0.1 6.6e-07 29.0 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 WD40 PF00400.32 OAG36214.1 - 1.4e-05 25.7 0.4 0.26 12.2 0.0 4.5 4 0 0 4 4 4 2 WD domain, G-beta repeat PQQ_3 PF13570.6 OAG36214.1 - 5.5e-05 23.5 0.6 1.7 9.2 0.0 4.0 3 0 0 3 3 3 2 PQQ-like domain ANAPC4_WD40 PF12894.7 OAG36214.1 - 0.00048 20.4 0.0 0.085 13.2 0.0 2.8 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 OAG36214.1 - 0.072 11.8 0.0 3.4 6.3 0.0 2.2 2 0 0 2 2 2 0 Nup133 N terminal like Methyltransf_23 PF13489.6 OAG36215.1 - 1.3e-15 57.6 0.0 2.1e-15 57.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG36215.1 - 2e-07 31.6 0.2 6.5e-06 26.8 0.1 2.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG36215.1 - 2e-05 25.2 0.0 0.001 19.8 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG36215.1 - 6.3e-05 23.5 0.0 0.00033 21.3 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG36215.1 - 0.00039 20.2 0.0 0.0014 18.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.17 OAG36215.1 - 0.0025 17.3 0.0 0.0044 16.5 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.14 OAG36215.1 - 0.015 14.9 0.0 0.029 13.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Ubie_methyltran PF01209.18 OAG36215.1 - 0.04 13.3 0.0 0.42 9.9 0.0 2.1 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Ribosomal_L18A PF01775.17 OAG36216.1 - 9.3e-55 183.9 0.3 1.2e-54 183.6 0.3 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A PCI PF01399.27 OAG36217.1 - 1.6e-05 25.3 0.1 6.6e-05 23.4 0.0 2.1 2 0 0 2 2 2 1 PCI domain TPR_12 PF13424.6 OAG36217.1 - 0.027 14.8 0.0 0.11 12.9 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF501 PF04417.12 OAG36217.1 - 0.074 12.9 0.1 0.26 11.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF501) BTB PF00651.31 OAG36218.1 - 5e-07 29.9 0.0 1.2e-06 28.7 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain GNT-I PF03071.15 OAG36218.1 - 0.1 11.4 0.0 0.19 10.4 0.0 1.4 1 0 0 1 1 1 0 GNT-I family Skp1_POZ PF03931.15 OAG36218.1 - 0.17 12.1 0.0 0.36 11.0 0.0 1.5 1 0 0 1 1 1 0 Skp1 family, tetramerisation domain CLTH PF10607.9 OAG36219.1 - 1.1e-28 100.0 0.0 2e-28 99.1 0.0 1.5 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 OAG36219.1 - 2.2e-06 27.6 2.2 4.7e-06 26.5 2.2 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Rtf2 PF04641.12 OAG36219.1 - 0.0058 16.0 0.1 0.0098 15.3 0.1 1.4 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_5 PF14634.6 OAG36219.1 - 0.0074 16.2 2.2 0.014 15.3 2.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 OAG36219.1 - 0.012 15.9 2.9 0.023 15.0 2.9 1.5 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.6 OAG36219.1 - 0.36 10.7 4.1 0.73 9.7 4.1 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Filament PF00038.21 OAG36220.1 - 0.00056 19.6 6.8 0.0014 18.3 3.5 2.4 2 1 0 2 2 2 1 Intermediate filament protein CEP63 PF17045.5 OAG36220.1 - 0.013 15.4 6.3 0.03 14.2 6.3 1.6 1 0 0 1 1 1 0 Centrosomal protein of 63 kDa PG_binding_1 PF01471.18 OAG36220.1 - 0.033 14.4 0.0 5.3 7.3 0.0 3.0 2 0 0 2 2 2 0 Putative peptidoglycan binding domain HTH_Tnp_Mu_2 PF09039.11 OAG36220.1 - 0.038 14.1 0.1 2.5 8.2 0.0 3.2 3 0 0 3 3 3 0 Mu DNA binding, I gamma subdomain Syntaxin-6_N PF09177.11 OAG36220.1 - 0.1 13.2 5.7 0.055 14.0 1.4 2.8 3 1 0 3 3 3 0 Syntaxin 6, N-terminal KLRAQ PF10205.9 OAG36220.1 - 0.11 12.8 1.9 12 6.2 0.1 2.7 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein DASH_Dam1 PF08653.10 OAG36220.1 - 0.56 10.1 1.5 1.3 8.9 0.2 2.3 3 0 0 3 3 3 0 DASH complex subunit Dam1 Tropomyosin_1 PF12718.7 OAG36220.1 - 1.5 9.0 9.3 1.2 9.3 6.6 2.2 2 0 0 2 2 2 0 Tropomyosin like zf-Tim10_DDP PF02953.15 OAG36221.1 - 2.2e-22 78.4 1.9 2.6e-22 78.2 1.9 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger CAAP1 PF15335.6 OAG36221.1 - 0.031 14.8 0.1 0.045 14.3 0.1 1.1 1 0 0 1 1 1 0 Caspase activity and apoptosis inhibitor 1 Tom5 PF10642.9 OAG36221.1 - 0.071 13.2 0.1 0.14 12.2 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial import receptor subunit or translocase tRNA-synt_2 PF00152.20 OAG36222.1 - 8.2e-59 199.2 0.0 9.5e-58 195.7 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.20 OAG36222.1 - 2.9e-05 23.7 0.2 0.0076 15.8 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA_anti-codon PF01336.25 OAG36222.1 - 0.00012 22.0 0.0 0.00021 21.2 0.0 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain SAD_SRA PF02182.17 OAG36223.1 - 5.1e-27 94.5 0.7 1.5e-26 93.0 0.1 1.9 2 0 0 2 2 2 1 SAD/SRA domain CBP_BcsS PF17036.5 OAG36224.1 - 0.074 13.0 0.2 0.12 12.3 0.2 1.2 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsS DUF4268 PF14088.6 OAG36224.1 - 0.2 11.5 0.0 0.36 10.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4268) APH PF01636.23 OAG36226.1 - 8.1e-17 61.9 0.0 1.5e-15 57.8 0.0 2.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 OAG36226.1 - 0.013 14.4 0.1 2.4 6.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) Fructosamin_kin PF03881.14 OAG36226.1 - 0.033 13.4 0.1 0.061 12.5 0.0 1.4 2 0 0 2 2 2 0 Fructosamine kinase CDC45 PF02724.14 OAG36227.1 - 0.62 8.3 7.7 0.91 7.7 7.7 1.2 1 0 0 1 1 1 0 CDC45-like protein SPX PF03105.19 OAG36227.1 - 2.5 7.9 10.5 2 8.3 5.3 2.0 2 0 0 2 2 2 0 SPX domain La PF05383.17 OAG36228.1 - 1.8e-20 72.7 0.0 3.1e-20 72.0 0.0 1.4 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 OAG36228.1 - 4e-08 33.0 0.1 1.1e-07 31.5 0.1 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cyclin_N PF00134.23 OAG36229.1 - 2.7e-10 40.1 0.0 1.7e-09 37.5 0.0 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain Exo70 PF03081.15 OAG36230.1 - 1.8e-79 267.5 0.0 5e-78 262.8 0.0 2.1 2 0 0 2 2 2 2 Exo70 exocyst complex subunit Herpes_BTRF1 PF04682.12 OAG36230.1 - 0.011 15.1 0.1 0.57 9.5 0.0 2.4 2 0 0 2 2 2 0 Herpesvirus BTRF1 protein conserved region PLA2_B PF01735.18 OAG36231.1 - 2.7e-24 85.4 0.0 1.1e-23 83.5 0.0 1.8 1 1 0 1 1 1 1 Lysophospholipase catalytic domain Phosphodiest PF01663.22 OAG36232.1 - 6.1e-92 309.0 0.8 8.4e-92 308.5 0.8 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 OAG36232.1 - 0.014 14.8 0.0 5.1 6.4 0.0 2.2 1 1 1 2 2 2 0 Sulfatase AATase PF07247.12 OAG36233.1 - 2.1e-19 69.5 0.0 6.5e-19 67.9 0.0 1.7 1 1 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.20 OAG36233.1 - 0.00049 18.9 0.0 0.009 14.7 0.0 2.2 2 0 0 2 2 2 1 Condensation domain RWP-RK PF02042.15 OAG36233.1 - 0.044 13.8 0.2 0.093 12.7 0.2 1.5 1 0 0 1 1 1 0 RWP-RK domain WES_acyltransf PF03007.16 OAG36233.1 - 0.099 12.4 0.0 0.22 11.2 0.0 1.6 2 0 0 2 2 2 0 Wax ester synthase-like Acyl-CoA acyltransferase domain Prolactin_RP PF15172.6 OAG36233.1 - 0.11 12.2 0.3 0.28 10.8 0.0 1.9 2 0 0 2 2 2 0 Prolactin-releasing peptide Abhydrolase_3 PF07859.13 OAG36234.1 - 4.1e-49 167.3 0.0 5.6e-49 166.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 OAG36234.1 - 1.4e-08 34.1 0.7 4.7e-08 32.4 0.7 1.7 1 1 0 1 1 1 1 Carboxylesterase family RIBIOP_C PF04950.12 OAG36235.1 - 4.5e-101 338.1 0.0 9.2e-101 337.1 0.0 1.5 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 OAG36235.1 - 1.1e-21 76.6 0.0 2.5e-21 75.6 0.0 1.6 1 0 0 1 1 1 1 AARP2CN (NUC121) domain Ank_2 PF12796.7 OAG36236.1 - 1.1e-62 208.6 0.1 1.3e-10 41.7 0.0 10.9 4 3 8 13 13 13 12 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAG36236.1 - 2.5e-57 190.6 0.8 8.4e-06 26.2 0.0 13.3 10 2 3 13 13 13 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG36236.1 - 2.2e-44 144.3 14.3 0.0018 18.6 0.1 18.9 19 0 0 19 19 19 7 Ankyrin repeat Ank PF00023.30 OAG36236.1 - 1.4e-28 98.0 20.8 0.013 15.9 0.1 16.1 17 1 1 18 18 18 5 Ankyrin repeat Ank_5 PF13857.6 OAG36236.1 - 6.8e-25 86.8 14.8 0.0078 16.5 0.0 13.1 10 4 5 15 15 15 7 Ankyrin repeats (many copies) Clr5 PF14420.6 OAG36236.1 - 2.7e-19 69.1 1.6 5.4e-19 68.2 1.6 1.5 1 0 0 1 1 1 1 Clr5 domain DUF2695 PF10905.8 OAG36236.1 - 0.19 12.0 0.9 7.4 6.9 0.1 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2695) Snapin_Pallidin PF14712.6 OAG36237.1 - 0.0056 17.1 7.0 0.012 16.0 0.3 3.1 2 0 0 2 2 2 1 Snapin/Pallidin SOGA PF11365.8 OAG36237.1 - 0.034 15.3 2.0 0.034 15.3 2.0 3.2 3 1 1 4 4 4 0 Protein SOGA Effector_1 PF04518.12 OAG36237.1 - 0.058 12.5 1.4 0.1 11.7 1.0 1.5 1 1 0 1 1 1 0 Effector from type III secretion system Cnd2 PF05786.14 OAG36237.1 - 0.086 11.5 4.4 0.24 10.0 4.4 1.7 1 0 0 1 1 1 0 Condensin complex subunit 2 DUF1515 PF07439.11 OAG36237.1 - 5.5 7.1 8.3 3 7.9 2.7 3.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) ABC_tran_CTD PF16326.5 OAG36237.1 - 5.8 7.2 9.3 19 5.6 3.7 4.0 3 1 0 3 3 3 0 ABC transporter C-terminal domain Bromodomain PF00439.25 OAG36238.1 - 1.5e-43 146.8 1.9 1.1e-20 73.5 0.0 2.5 2 0 0 2 2 2 2 Bromodomain BET PF17035.5 OAG36238.1 - 1.5e-17 63.5 0.1 5.2e-17 61.8 0.1 2.0 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation V_ATPase_I PF01496.19 OAG36238.1 - 0.074 11.0 9.8 0.11 10.4 9.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family XRN1_DBM PF18245.1 OAG36238.1 - 0.14 12.1 3.3 0.24 11.4 0.0 3.3 3 0 0 3 3 3 0 5-3 exonuclease XRN1 DCP1-binding motif Allexi_40kDa PF05549.11 OAG36238.1 - 0.29 10.6 5.0 0.25 10.8 2.9 2.0 2 0 0 2 2 2 0 Allexivirus 40kDa protein Hid1 PF12722.7 OAG36238.1 - 0.55 8.3 12.3 1.5 6.8 12.3 1.7 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CDC45 PF02724.14 OAG36238.1 - 0.57 8.4 18.9 1.2 7.3 18.9 1.5 1 0 0 1 1 1 0 CDC45-like protein HSNSD PF12062.8 OAG36238.1 - 1.8 7.2 3.6 3 6.5 3.6 1.2 1 0 0 1 1 1 0 heparan sulfate-N-deacetylase PI3K_1B_p101 PF10486.9 OAG36238.1 - 6.2 4.5 11.8 9.1 3.9 11.8 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Utp12 PF04003.12 OAG36239.1 - 2.8e-20 72.6 0.1 4.7e-20 71.9 0.1 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 OAG36239.1 - 0.0089 16.3 0.0 1.3 9.4 0.0 3.4 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OAG36240.1 - 9e-05 23.2 3.8 0.024 15.5 0.1 4.0 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG36240.1 - 0.024 14.9 0.0 5.7 7.3 0.0 3.3 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain PPTA PF01239.22 OAG36241.1 - 1.3e-36 123.3 17.9 5.5e-08 32.3 1.8 5.7 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat DUF406 PF04175.12 OAG36241.1 - 0.15 12.5 1.6 0.86 10.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF406) RabGAP-TBC PF00566.18 OAG36242.1 - 1.8e-45 155.2 0.0 1.8e-45 155.2 0.0 2.7 3 0 0 3 3 3 1 Rab-GTPase-TBC domain AviRa PF11599.8 OAG36242.1 - 0.12 11.8 4.6 0.25 10.8 4.6 1.4 1 0 0 1 1 1 0 RRNA methyltransferase AviRa Cnn_1N PF07989.11 OAG36242.1 - 0.22 11.7 23.1 0.28 11.3 5.6 3.8 2 2 1 3 3 3 0 Centrosomin N-terminal motif 1 YabA PF06156.13 OAG36242.1 - 0.34 11.6 19.3 4.6 7.9 5.8 3.7 2 1 1 3 3 3 0 Initiation control protein YabA HALZ PF02183.18 OAG36242.1 - 1.6 9.0 7.4 4.5 7.6 0.6 2.9 2 0 0 2 2 2 0 Homeobox associated leucine zipper Fez1 PF06818.15 OAG36242.1 - 4 7.8 28.7 1.4 9.3 23.7 2.4 2 0 0 2 2 2 0 Fez1 Tropomyosin_1 PF12718.7 OAG36242.1 - 9 6.4 31.3 0.58 10.3 8.7 3.1 2 1 1 3 3 3 0 Tropomyosin like AMP-binding PF00501.28 OAG36243.1 - 7.3e-73 245.6 0.0 9e-73 245.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG36243.1 - 3.1e-06 28.1 0.0 7.1e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Ctf8 PF09696.10 OAG36245.1 - 1.3e-37 129.3 0.2 2.9e-37 128.2 0.2 1.6 1 1 0 1 1 1 1 Ctf8 Glyco_hydro_32N PF00251.20 OAG36246.1 - 1.7e-47 162.5 0.0 2.6e-47 161.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 OAG36246.1 - 1.7e-20 73.6 0.0 3.9e-20 72.4 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal HTH_17 PF12728.7 OAG36246.1 - 0.03 14.5 0.0 0.08 13.1 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain DUF4975 PF16346.5 OAG36246.1 - 0.098 12.7 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4975) ATP-synt_ab PF00006.25 OAG36247.1 - 2.9e-67 226.4 0.0 3.8e-67 226.1 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 OAG36247.1 - 6.9e-14 52.1 0.2 1.2e-13 51.3 0.2 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Phage_1_1 PF08200.11 OAG36247.1 - 0.17 12.3 0.1 0.4 11.1 0.1 1.5 1 0 0 1 1 1 0 Bacteriophage 1.1 Protein MFS_1 PF07690.16 OAG36248.1 - 3.4e-15 55.8 15.7 3.4e-15 55.8 15.7 2.5 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG36248.1 - 1.1e-07 31.0 0.2 1.1e-07 31.0 0.2 1.9 1 1 1 2 2 2 1 Sugar (and other) transporter Abhydrolase_1 PF00561.20 OAG36249.1 - 2.8e-18 66.5 0.0 7e-18 65.2 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG36249.1 - 5.4e-16 59.9 0.9 9.2e-16 59.1 0.9 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG36249.1 - 1.8e-12 47.1 0.0 3.4e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 OAG36249.1 - 0.00021 20.1 0.0 0.00031 19.6 0.0 1.3 1 0 0 1 1 1 1 Ndr family Thioesterase PF00975.20 OAG36249.1 - 0.0047 17.1 0.0 0.013 15.6 0.0 1.7 1 1 0 1 1 1 1 Thioesterase domain Esterase PF00756.20 OAG36249.1 - 0.078 12.6 0.1 0.15 11.7 0.1 1.4 1 0 0 1 1 1 0 Putative esterase Abhydrolase_4 PF08386.10 OAG36249.1 - 0.13 12.3 0.0 0.39 10.9 0.0 1.8 2 0 0 2 2 2 0 TAP-like protein Clr5 PF14420.6 OAG36250.1 - 8.5e-20 70.7 3.0 1.8e-19 69.7 3.0 1.6 1 0 0 1 1 1 1 Clr5 domain TPR_12 PF13424.6 OAG36250.1 - 0.0056 16.9 2.7 3.1 8.1 0.4 3.4 4 0 0 4 4 4 2 Tetratricopeptide repeat Dicty_CAR PF05462.11 OAG36251.1 - 9.1e-10 38.1 4.8 9.1e-10 38.1 4.8 1.8 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor Git3 PF11710.8 OAG36251.1 - 9.1e-07 28.9 6.6 1.4e-06 28.2 6.6 1.2 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Frizzled PF01534.17 OAG36251.1 - 1.6 7.7 12.1 4.5 6.2 6.7 2.3 1 1 1 2 2 2 0 Frizzled/Smoothened family membrane region PPI_Ypi1 PF07491.11 OAG36252.1 - 1.5e-24 85.6 7.3 7.4e-24 83.3 7.3 2.1 1 1 0 1 1 1 1 Protein phosphatase inhibitor CDC45 PF02724.14 OAG36252.1 - 0.76 8.0 5.5 0.89 7.8 5.5 1.1 1 0 0 1 1 1 0 CDC45-like protein YL1 PF05764.13 OAG36252.1 - 1 9.4 5.8 0.35 11.0 3.4 1.4 2 0 0 2 2 2 0 YL1 nuclear protein CCDC106 PF15794.5 OAG36252.1 - 5.3 6.7 5.1 4.2 7.0 3.9 1.5 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 106 CRM1_C PF08767.11 OAG36253.1 - 1.9e-136 454.4 4.4 1.9e-136 454.4 4.4 3.0 3 1 0 4 4 4 1 CRM1 C terminal Xpo1 PF08389.12 OAG36253.1 - 1.2e-38 132.5 10.5 3.7e-38 130.9 7.0 3.5 3 1 0 3 3 3 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 OAG36253.1 - 2.2e-33 113.7 4.2 3.4e-33 113.1 2.9 2.1 2 0 0 2 2 2 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 OAG36253.1 - 1e-29 102.3 1.2 1e-29 102.3 1.2 2.6 3 0 0 3 3 3 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 OAG36253.1 - 7.7e-20 70.1 2.7 1.7e-19 69.0 2.7 1.7 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 OAG36253.1 - 3.6e-10 39.6 0.0 1.4e-09 37.7 0.0 2.1 1 0 0 1 1 1 1 Importin-beta N-terminal domain DUF3385 PF11865.8 OAG36253.1 - 0.0061 16.5 3.4 0.12 12.2 0.0 4.0 4 0 0 4 4 4 1 Domain of unknown function (DUF3385) Hemocyanin_M PF00372.19 OAG36253.1 - 0.04 13.1 0.0 0.084 12.1 0.0 1.4 1 0 0 1 1 1 0 Hemocyanin, copper containing domain Pre-PUA PF17832.1 OAG36253.1 - 0.074 13.7 0.4 1.2 9.8 0.0 3.1 3 0 0 3 3 3 0 Pre-PUA-like domain bZIP_2 PF07716.15 OAG36254.1 - 7.1e-13 48.4 16.8 1.5e-12 47.4 16.8 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 OAG36254.1 - 0.00023 21.2 12.5 0.00023 21.2 12.5 1.6 2 0 0 2 2 2 1 bZIP transcription factor TSC22 PF01166.18 OAG36254.1 - 0.041 14.2 2.4 0.085 13.2 2.4 1.5 1 0 0 1 1 1 0 TSC-22/dip/bun family UPF0242 PF06785.11 OAG36254.1 - 0.14 12.2 12.4 0.22 11.6 12.4 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus CBM-like PF14683.6 OAG36254.1 - 0.22 11.4 2.2 0.27 11.1 0.9 1.7 2 0 0 2 2 2 0 Polysaccharide lyase family 4, domain III OmpH PF03938.14 OAG36254.1 - 0.47 10.8 15.0 0.82 10.0 15.0 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) XhlA PF10779.9 OAG36254.1 - 0.66 10.2 4.2 1.3 9.3 4.2 1.4 1 0 0 1 1 1 0 Haemolysin XhlA FapA PF03961.13 OAG36254.1 - 1.4 7.5 7.7 1.7 7.1 7.7 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A YabA PF06156.13 OAG36254.1 - 8.2 7.1 8.9 6.3 7.5 6.9 1.8 1 1 1 2 2 2 0 Initiation control protein YabA CENP-N PF05238.13 OAG36255.1 - 1.5e-81 274.8 0.9 4.5e-62 210.7 0.9 2.0 1 1 1 2 2 2 2 Kinetochore protein CHL4 like adh_short_C2 PF13561.6 OAG36256.1 - 4.5e-26 91.8 0.2 5.9e-26 91.5 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG36256.1 - 3.2e-17 62.6 0.1 4.4e-17 62.2 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG36256.1 - 9.5e-06 25.6 0.8 1.4e-05 25.1 0.8 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 OAG36256.1 - 0.0075 16.2 0.1 0.013 15.4 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ADH_zinc_N PF00107.26 OAG36256.1 - 0.0093 16.0 0.3 0.022 14.7 0.2 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 OAG36256.1 - 0.013 14.8 0.0 0.022 14.1 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 OAG36256.1 - 0.014 15.8 0.1 0.031 14.7 0.1 1.5 2 0 0 2 2 2 0 Putative NAD(P)-binding Sacchrp_dh_NADP PF03435.18 OAG36256.1 - 0.028 14.7 0.1 0.046 14.0 0.1 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Oxidored_nitro PF00148.19 OAG36256.1 - 0.045 12.5 0.0 0.062 12.0 0.0 1.2 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase ADH_zinc_N PF00107.26 OAG36257.1 - 1.9e-24 86.1 0.0 3.9e-24 85.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Fungal_trans PF04082.18 OAG36257.1 - 1.7e-21 76.4 0.1 2.7e-21 75.8 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain ADH_zinc_N_2 PF13602.6 OAG36257.1 - 3.9e-21 76.5 0.0 1e-20 75.1 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG36257.1 - 6.6e-05 22.8 0.3 0.00012 21.9 0.3 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Gal4_dimer PF03902.13 OAG36257.1 - 0.0006 19.9 0.8 0.0016 18.5 0.8 1.7 1 0 0 1 1 1 1 Gal4-like dimerisation domain CAP_N PF01213.19 OAG36258.1 - 5.5e-114 380.9 0.0 8.2e-114 380.3 0.0 1.3 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 OAG36258.1 - 2.4e-57 192.9 2.4 3.3e-57 192.5 2.4 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.12 OAG36258.1 - 0.4 10.4 3.8 0.7 9.6 2.5 1.8 1 1 1 2 2 2 0 Tubulin binding cofactor C Metallophos PF00149.28 OAG36259.1 - 1e-11 45.8 0.8 7.3e-11 43.0 0.3 2.3 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OAG36259.1 - 7.2e-08 32.8 0.2 9.2e-05 22.7 0.0 2.3 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain AIM3 PF17096.5 OAG36259.1 - 7.8 7.5 10.6 14 6.7 9.0 2.1 2 1 0 2 2 2 0 Altered inheritance of mitochondria protein 3 PPR_long PF17177.4 OAG36260.1 - 0.014 14.8 0.0 0.077 12.3 0.0 1.9 2 0 0 2 2 2 0 Pentacotripeptide-repeat region of PRORP Stork_head PF10264.9 OAG36260.1 - 0.023 14.8 0.4 0.26 11.5 0.0 2.6 3 0 0 3 3 3 0 Winged helix Storkhead-box1 domain PPR_3 PF13812.6 OAG36260.1 - 0.071 13.2 0.2 32 4.7 0.0 3.6 4 0 0 4 4 4 0 Pentatricopeptide repeat domain DUF3446 PF11928.8 OAG36260.1 - 0.77 10.1 5.1 1.9 8.8 5.1 1.6 1 0 0 1 1 1 0 Early growth response N-terminal domain Abhydrolase_6 PF12697.7 OAG36261.1 - 2.1e-16 61.2 0.0 2.4e-16 61.0 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF722 PF05263.11 OAG36262.1 - 0.022 15.0 0.2 3 8.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF722) DASH_Duo1 PF08651.10 OAG36262.1 - 0.031 14.0 0.6 0.069 12.9 0.6 1.5 1 0 0 1 1 1 0 DASH complex subunit Duo1 MaAIMP_sms PF16951.5 OAG36262.1 - 0.17 11.7 0.5 0.39 10.5 0.5 1.5 1 0 0 1 1 1 0 Putative methionine and alanine importer, small subunit LPG_synthase_TM PF03706.13 OAG36262.1 - 0.22 11.0 3.5 0.33 10.5 3.5 1.2 1 0 0 1 1 1 0 Lysylphosphatidylglycerol synthase TM region HemY_N PF07219.13 OAG36262.1 - 0.48 10.6 2.9 1 9.6 2.9 1.4 1 0 0 1 1 1 0 HemY protein N-terminus TALPID3 PF15324.6 OAG36262.1 - 0.76 7.4 5.5 1.1 6.8 5.5 1.1 1 0 0 1 1 1 0 Hedgehog signalling target CTP_transf_1 PF01148.20 OAG36263.1 - 5.5e-79 265.7 23.6 6.9e-79 265.4 23.6 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family Pinin_SDK_N PF04697.13 OAG36263.1 - 0.42 11.2 1.7 0.65 10.6 1.7 1.2 1 0 0 1 1 1 0 pinin/SDK conserved region DUF3636 PF12331.8 OAG36264.1 - 1.1e-40 138.9 0.1 2.5e-40 137.7 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3636) LCD1 PF09798.9 OAG36264.1 - 2.1e-05 23.3 6.9 0.0039 15.8 0.5 3.0 2 1 1 3 3 3 2 DNA damage checkpoint protein Golgin_A5 PF09787.9 OAG36264.1 - 0.0037 16.8 11.0 0.0063 16.0 11.0 1.3 1 0 0 1 1 1 1 Golgin subfamily A member 5 Lebercilin PF15619.6 OAG36264.1 - 0.011 15.4 5.0 0.011 15.4 5.0 2.3 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease CALCOCO1 PF07888.11 OAG36264.1 - 0.016 14.1 10.5 0.025 13.5 10.5 1.2 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Phage_GPO PF05929.11 OAG36264.1 - 0.088 12.4 8.1 0.18 11.4 8.1 1.4 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase JIP_LZII PF16471.5 OAG36264.1 - 0.23 11.7 5.6 0.65 10.2 0.3 2.6 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II Jnk-SapK_ap_N PF09744.9 OAG36264.1 - 0.25 11.5 10.8 0.51 10.6 10.8 1.5 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 UPF0242 PF06785.11 OAG36264.1 - 0.35 11.0 7.2 1.1 9.4 7.2 1.8 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus HIP1_clath_bdg PF16515.5 OAG36264.1 - 0.71 10.5 13.5 0.74 10.5 3.7 2.5 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Tho2 PF11262.8 OAG36264.1 - 1.1 8.4 7.6 0.92 8.6 5.9 1.7 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 NICE-3 PF07406.11 OAG36265.1 - 0.0034 17.4 0.0 0.009 16.0 0.0 1.7 1 0 0 1 1 1 1 NICE-3 protein DUF4129 PF13559.6 OAG36265.1 - 0.0064 16.7 0.0 0.015 15.5 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4129) Macoilin PF09726.9 OAG36265.1 - 1.5 7.2 10.0 2.1 6.8 10.0 1.1 1 0 0 1 1 1 0 Macoilin family DUF1993 PF09351.10 OAG36266.1 - 9.8e-55 185.1 0.0 1.1e-54 184.9 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) Elf-1_N PF12310.8 OAG36268.1 - 0.018 15.5 0.1 0.038 14.5 0.1 1.6 1 0 0 1 1 1 0 Transcription factor protein N terminal S1 PF00575.23 OAG36268.1 - 0.44 10.9 2.4 1.3 9.4 0.3 2.4 2 0 0 2 2 2 0 S1 RNA binding domain DUF3655 PF12379.8 OAG36269.1 - 0.04 14.2 0.1 0.067 13.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3655) p450 PF00067.22 OAG36270.1 - 0.00012 21.0 0.0 0.00012 21.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ATG16 PF08614.11 OAG36272.1 - 0.0076 16.5 7.1 0.026 14.8 7.0 1.9 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) BRE1 PF08647.11 OAG36272.1 - 0.0082 16.2 1.3 0.0082 16.2 1.3 1.8 1 1 0 1 1 1 1 BRE1 E3 ubiquitin ligase DUF4407 PF14362.6 OAG36272.1 - 0.013 14.9 4.5 0.021 14.2 4.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Tmemb_cc2 PF10267.9 OAG36272.1 - 0.92 8.6 6.0 0.12 11.5 1.7 1.6 2 0 0 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein MbeD_MobD PF04899.12 OAG36272.1 - 2.3 8.4 4.8 2.8 8.1 2.1 2.4 2 0 0 2 2 2 0 MbeD/MobD like DUF148 PF02520.17 OAG36272.1 - 2.6 8.2 6.8 5.2 7.2 6.8 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF148 RVT_1 PF00078.27 OAG36273.1 - 1e-15 57.9 0.0 1.5e-15 57.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Cyclase PF04199.13 OAG36276.1 - 7e-05 23.1 0.0 9.5e-05 22.7 0.0 1.3 1 1 0 1 1 1 1 Putative cyclase DUF4767 PF15983.5 OAG36280.1 - 0.042 14.1 3.6 2.6 8.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4767) DUF2321 PF10083.9 OAG36283.1 - 0.047 13.3 0.0 0.076 12.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) DUF3663 PF12404.8 OAG36284.1 - 0.15 12.1 0.0 0.35 11.0 0.0 1.6 1 0 0 1 1 1 0 Peptidase DUF3506 PF12014.8 OAG36286.1 - 5.8e-05 23.1 0.0 0.00011 22.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3506) Fe-ADH PF00465.19 OAG36287.1 - 7.7e-09 34.8 0.0 9.5e-09 34.5 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase DUF2207 PF09972.9 OAG36290.1 - 0.00056 18.8 4.3 0.00081 18.3 4.3 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) DUF983 PF06170.12 OAG36290.1 - 0.0017 18.7 2.0 0.0017 18.7 2.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF983) DUF805 PF05656.14 OAG36290.1 - 3.6 8.1 6.4 12 6.4 6.4 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF805) Wzy_C PF04932.15 OAG36290.1 - 5.6 6.6 10.8 0.74 9.4 6.7 1.7 2 0 0 2 2 2 0 O-Antigen ligase Baculo_PP31 PF05311.11 OAG36291.1 - 0.073 12.6 0.0 0.1 12.1 0.0 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Metal_resist PF13801.6 OAG36292.1 - 0.11 12.7 1.6 0.16 12.2 1.6 1.2 1 0 0 1 1 1 0 Heavy-metal resistance SET PF00856.28 OAG36293.1 - 1.1e-11 45.4 0.1 1.2e-09 38.7 0.1 2.2 1 1 0 1 1 1 1 SET domain Methyltransf_23 PF13489.6 OAG36294.1 - 5.1e-10 39.4 0.0 1e-09 38.5 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG36294.1 - 2e-07 31.6 0.0 9.1e-07 29.5 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG36294.1 - 2.3e-06 27.5 0.0 6e-05 22.9 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG36294.1 - 2.8e-05 24.7 0.0 0.00014 22.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OAG36294.1 - 0.00053 19.6 0.0 0.0018 17.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_12 PF08242.12 OAG36294.1 - 0.0017 19.1 0.0 0.012 16.3 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 OAG36294.1 - 0.0083 15.9 0.0 0.011 15.4 0.0 1.1 1 0 0 1 1 1 1 Met-10+ like-protein PrmA PF06325.13 OAG36294.1 - 0.024 14.0 0.0 0.038 13.4 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.9 OAG36294.1 - 0.032 13.9 0.0 0.05 13.3 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase FtsJ PF01728.19 OAG36294.1 - 0.045 13.9 0.0 0.092 12.9 0.0 1.4 2 0 0 2 2 2 0 FtsJ-like methyltransferase Ubie_methyltran PF01209.18 OAG36294.1 - 0.071 12.4 0.0 0.78 9.0 0.0 2.0 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 OAG36294.1 - 0.12 11.8 0.0 0.24 10.8 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase YXWGXW PF12779.7 OAG36294.1 - 0.17 12.1 5.3 0.25 11.5 3.4 2.2 2 0 0 2 2 2 0 YXWGXW repeat (2 copies) SET PF00856.28 OAG36296.1 - 4.5e-08 33.7 0.0 9.1e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 SET domain WD40 PF00400.32 OAG36297.1 - 3.9e-18 65.5 2.9 0.0011 19.8 0.0 5.6 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG36297.1 - 2.7e-08 34.0 0.0 4.6e-05 23.6 0.0 4.0 1 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OAG36297.1 - 0.0055 15.7 0.1 0.23 10.4 0.0 2.8 2 2 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 OAG36297.1 - 0.0059 15.3 0.3 0.036 12.7 0.1 2.1 1 1 1 2 2 2 1 Nucleoporin Nup120/160 WD40_like PF17005.5 OAG36297.1 - 0.02 14.3 0.0 0.033 13.5 0.0 1.3 1 0 0 1 1 1 0 WD40-like domain Kelch_4 PF13418.6 OAG36298.1 - 2.2e-24 85.2 3.7 6.4e-06 26.1 0.0 4.9 4 0 0 4 4 4 4 Galactose oxidase, central domain Kelch_6 PF13964.6 OAG36298.1 - 2.8e-22 78.2 1.8 8.8e-06 25.8 0.1 4.7 2 1 2 4 4 4 4 Kelch motif Kelch_5 PF13854.6 OAG36298.1 - 6.7e-22 77.0 0.4 1.3e-05 25.1 0.0 4.5 4 0 0 4 4 4 4 Kelch motif Kelch_2 PF07646.15 OAG36298.1 - 2.5e-19 68.4 1.8 3.4e-05 23.6 0.0 4.7 4 0 0 4 4 4 4 Kelch motif Kelch_1 PF01344.25 OAG36298.1 - 1.5e-17 62.9 0.2 1.9e-06 27.3 0.0 4.4 4 0 0 4 4 4 3 Kelch motif Kelch_3 PF13415.6 OAG36298.1 - 1.5e-16 60.2 6.3 4.8e-08 33.1 0.1 5.9 6 0 0 6 6 6 3 Galactose oxidase, central domain BTB PF00651.31 OAG36298.1 - 2.7e-10 40.5 0.0 5.1e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 OAG36298.1 - 0.0066 16.5 0.0 0.017 15.2 0.0 1.6 1 0 0 1 1 1 1 BTB And C-terminal Kelch ANAPC4_WD40 PF12894.7 OAG36299.1 - 8.2e-17 61.3 7.3 3.1e-06 27.4 0.2 4.3 3 1 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OAG36299.1 - 8.1e-16 58.1 17.0 0.00036 21.3 0.1 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat Ge1_WD40 PF16529.5 OAG36299.1 - 5.4e-06 25.6 0.0 0.0011 18.0 0.0 3.4 1 1 2 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 OAG36299.1 - 5.1e-05 23.2 0.2 0.007 16.3 0.1 2.4 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A CK2S PF15011.6 OAG36300.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.7 1 0 0 1 1 1 0 Casein Kinase 2 substrate Sugar_tr PF00083.24 OAG36301.1 - 4.5e-106 355.4 16.2 5.1e-106 355.2 16.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG36301.1 - 3.4e-30 105.2 21.3 6.5e-29 101.0 11.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 OAG36301.1 - 0.00053 18.5 1.7 0.00053 18.5 1.7 2.0 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Phage_holin_3_2 PF04550.12 OAG36301.1 - 0.068 13.7 4.2 0.31 11.6 4.2 2.2 1 0 0 1 1 1 0 Phage holin family 2 Herpes_UL73 PF03554.13 OAG36301.1 - 0.31 11.1 2.2 0.8 9.8 0.2 2.7 2 1 1 3 3 3 0 UL73 viral envelope glycoprotein OATP PF03137.20 OAG36301.1 - 3.6 5.8 9.6 2.1 6.5 1.4 2.8 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family zf-CCHC PF00098.23 OAG36302.1 - 1.1e-23 82.1 22.9 3.2e-09 36.4 2.4 3.2 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC_5 PF14787.6 OAG36302.1 - 4.3e-10 39.1 11.5 0.0014 18.3 0.1 3.3 1 1 2 3 3 3 3 GAG-polyprotein viral zinc-finger zf-CCHC_3 PF13917.6 OAG36302.1 - 5.4e-06 26.3 13.6 0.0059 16.5 0.6 3.1 2 1 1 3 3 3 3 Zinc knuckle zf-CCHC_4 PF14392.6 OAG36302.1 - 0.001 18.7 12.3 0.22 11.3 0.7 3.1 3 0 0 3 3 3 3 Zinc knuckle HscB_4_cys PF18256.1 OAG36302.1 - 0.11 12.3 6.7 8.6 6.3 0.1 3.7 3 0 0 3 3 3 0 Co-chaperone HscB tetracysteine metal binding motif AdoHcyase_NAD PF00670.21 OAG36302.1 - 0.16 12.1 0.2 0.23 11.5 0.2 1.3 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain zf-ribbon_3 PF13248.6 OAG36302.1 - 5.7 6.5 15.2 7.1 6.2 0.5 3.3 3 0 0 3 3 3 0 zinc-ribbon domain UDPGP PF01704.18 OAG36303.1 - 8.3e-55 186.1 0.0 1.1e-54 185.7 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Pro_isomerase PF00160.21 OAG36304.1 - 1.9e-34 119.2 0.0 2.9e-34 118.6 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 OAG36304.1 - 3.4e-16 58.8 0.1 6.8e-16 57.9 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Zn_clus PF00172.18 OAG36305.1 - 1.4e-07 31.5 9.1 1.4e-07 31.5 9.1 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_S24e PF01282.19 OAG36306.1 - 3.4e-34 116.7 0.2 6e-34 115.8 0.1 1.5 1 1 0 1 1 1 1 Ribosomal protein S24e RRXRR PF14239.6 OAG36306.1 - 0.031 14.2 3.2 0.043 13.7 2.8 1.5 1 1 0 1 1 1 0 RRXRR protein Methyltransf_16 PF10294.9 OAG36307.1 - 3.5e-20 72.4 0.0 5.3e-20 71.9 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 OAG36307.1 - 0.00072 19.0 0.0 0.0013 18.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 OAG36307.1 - 0.001 18.9 0.0 0.0031 17.4 0.0 1.8 2 1 0 2 2 2 1 Methyltransferase domain Met_10 PF02475.16 OAG36307.1 - 0.0056 16.4 0.0 0.01 15.6 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein MTS PF05175.14 OAG36307.1 - 0.0069 15.9 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 OAG36307.1 - 0.012 16.3 0.0 0.031 15.0 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.15 OAG36307.1 - 0.17 11.5 0.0 0.45 10.1 0.0 1.6 2 0 0 2 2 2 0 Conserved hypothetical protein 95 HSP70 PF00012.20 OAG36308.1 - 0.0025 16.1 0.0 0.007 14.6 0.0 1.7 1 1 0 1 1 1 1 Hsp70 protein DUF937 PF06078.11 OAG36309.1 - 0.11 13.1 4.1 0.49 11.0 0.7 2.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF937) Peptidase_S46 PF10459.9 OAG36309.1 - 3.2 6.3 22.1 0.36 9.4 17.2 1.7 1 1 0 1 1 1 0 Peptidase S46 HTH_32 PF13565.6 OAG36310.1 - 0.015 15.9 0.4 0.022 15.4 0.4 1.4 1 0 0 1 1 1 0 Homeodomain-like domain DnaJ PF00226.31 OAG36311.1 - 3e-12 46.5 0.0 7e-12 45.3 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain Lebercilin PF15619.6 OAG36311.1 - 0.011 15.4 25.2 0.025 14.2 19.3 2.3 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Phage_GP20 PF06810.11 OAG36311.1 - 0.72 9.6 12.7 0.36 10.6 0.3 3.0 2 1 0 3 3 3 0 Phage minor structural protein GP20 MCU PF04678.13 OAG36311.1 - 0.76 9.9 3.1 2 8.5 3.1 1.8 1 0 0 1 1 1 0 Mitochondrial calcium uniporter Tropomyosin_1 PF12718.7 OAG36311.1 - 0.96 9.6 33.5 0.93 9.6 25.5 3.3 2 1 0 2 2 2 0 Tropomyosin like APG6_N PF17675.1 OAG36311.1 - 2 9.0 25.2 8.3 7.0 1.3 2.7 1 1 1 2 2 2 0 Apg6 coiled-coil region ERM PF00769.19 OAG36311.1 - 5.9 6.6 27.1 3.4 7.4 18.0 2.5 1 1 1 2 2 2 0 Ezrin/radixin/moesin family HALZ PF02183.18 OAG36311.1 - 7.9 6.8 7.7 43 4.4 0.3 3.6 2 1 1 3 3 3 0 Homeobox associated leucine zipper BRE1 PF08647.11 OAG36311.1 - 9.2 6.4 14.9 2 8.5 8.8 2.7 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase Fungal_trans_2 PF11951.8 OAG36313.1 - 2.2e-07 30.0 0.2 3.7e-07 29.3 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DNApol3-delta_C PF09115.10 OAG36313.1 - 1 9.9 4.4 13 6.3 0.1 2.8 3 0 0 3 3 3 0 DNA polymerase III, delta subunit, C terminal GFA PF04828.14 OAG36314.1 - 2.1e-12 47.2 1.0 4.5e-12 46.1 1.0 1.6 1 1 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Tyrosinase PF00264.20 OAG36315.1 - 2e-53 182.0 1.7 2.6e-53 181.6 1.7 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase DUF202 PF02656.15 OAG36316.1 - 8.1 7.0 8.6 1.7 9.2 1.3 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF202) Aldedh PF00171.22 OAG36317.1 - 1.3e-155 518.5 0.5 1.5e-155 518.3 0.5 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family p450 PF00067.22 OAG36318.1 - 3.8e-51 174.3 0.0 2.3e-49 168.4 0.0 2.5 1 1 0 1 1 1 1 Cytochrome P450 G6PD_N PF00479.22 OAG36318.1 - 0.066 13.8 0.4 0.1 13.2 0.4 1.2 1 0 0 1 1 1 0 Glucose-6-phosphate dehydrogenase, NAD binding domain PsbT PF01405.17 OAG36318.1 - 3.1 7.7 4.6 8.4 6.3 4.6 1.7 1 0 0 1 1 1 0 Photosystem II reaction centre T protein Aldedh PF00171.22 OAG36319.1 - 5.1e-32 111.0 0.0 6.5e-32 110.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family TRI12 PF06609.13 OAG36320.1 - 1.8e-51 175.3 23.1 2.1e-51 175.1 23.1 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG36320.1 - 3.6e-21 75.5 51.1 3.4e-19 69.0 53.0 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.6 OAG36320.1 - 3.5e-05 22.6 4.5 3.5e-05 22.6 4.5 3.1 3 1 1 4 4 4 2 MFS/sugar transport protein Sugar_tr PF00083.24 OAG36320.1 - 0.00041 19.3 8.9 0.00041 19.3 8.9 3.0 3 0 0 3 3 3 1 Sugar (and other) transporter Phage_holin_5_2 PF16079.5 OAG36320.1 - 0.078 13.3 18.8 0.2 12.0 3.9 4.6 3 1 0 3 3 3 0 Phage holin family Hol44, in holin superfamily V DUF3425 PF11905.8 OAG36321.1 - 2.5e-24 85.6 0.1 4.5e-24 84.8 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 OAG36321.1 - 0.00019 21.5 17.6 0.012 15.7 0.5 2.8 3 0 0 3 3 3 2 bZIP transcription factor DivIC PF04977.15 OAG36321.1 - 0.002 17.8 2.9 0.0082 15.9 0.0 2.3 2 0 0 2 2 2 1 Septum formation initiator NEMO PF11577.8 OAG36321.1 - 0.0063 16.5 0.4 0.0063 16.5 0.4 1.8 2 0 0 2 2 2 1 NF-kappa-B essential modulator NEMO ZapB PF06005.12 OAG36321.1 - 0.0067 16.9 0.1 0.0067 16.9 0.1 2.0 2 0 0 2 2 2 1 Cell division protein ZapB bZIP_2 PF07716.15 OAG36321.1 - 0.016 15.3 11.0 0.14 12.3 0.3 2.4 2 0 0 2 2 2 0 Basic region leucine zipper Fmp27_WPPW PF10359.9 OAG36321.1 - 0.082 11.7 1.1 0.11 11.3 1.1 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain TSC22 PF01166.18 OAG36321.1 - 0.082 13.2 1.0 0.18 12.2 0.5 1.8 1 1 0 1 1 1 0 TSC-22/dip/bun family FAD_binding_3 PF01494.19 OAG36322.1 - 1.5e-15 57.3 0.0 2.4e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain ADC PF06314.11 OAG36322.1 - 7.5e-13 48.6 0.0 1.5e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) Pyr_redox_2 PF07992.14 OAG36322.1 - 4.2e-07 29.5 1.7 1.1e-06 28.1 1.7 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAG36322.1 - 4e-05 22.9 0.3 0.00012 21.3 0.1 1.8 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 OAG36322.1 - 0.00011 22.0 0.3 0.00032 20.4 0.1 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAG36322.1 - 0.00013 22.2 0.4 0.00098 19.3 0.2 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 OAG36322.1 - 0.00035 19.7 1.3 0.0011 18.2 1.3 1.7 1 1 0 1 1 1 1 Lycopene cyclase protein GIDA PF01134.22 OAG36322.1 - 0.0084 15.2 0.3 0.014 14.5 0.3 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.14 OAG36322.1 - 0.022 13.5 0.5 0.056 12.1 0.1 1.8 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox PF00070.27 OAG36322.1 - 0.047 14.3 0.1 0.13 12.8 0.1 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG36322.1 - 0.076 12.3 0.1 0.37 10.0 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 OAG36322.1 - 0.11 11.7 0.2 0.24 10.6 0.2 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Abhydrolase_1 PF00561.20 OAG36323.1 - 8.7e-16 58.3 0.1 1.3e-11 44.7 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG36323.1 - 7.8e-08 33.2 5.1 7.8e-08 33.2 5.1 1.6 1 1 1 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG36323.1 - 4.6e-07 29.3 0.0 2.7e-06 26.8 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 OAG36323.1 - 0.00051 20.0 0.0 0.0011 18.9 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OAG36323.1 - 0.002 17.7 0.0 0.0045 16.5 0.0 1.5 2 0 0 2 2 2 1 Prolyl oligopeptidase family Esterase PF00756.20 OAG36323.1 - 0.12 12.0 0.1 0.18 11.4 0.1 1.3 1 0 0 1 1 1 0 Putative esterase Abhydrolase_2 PF02230.16 OAG36323.1 - 0.13 12.1 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Pyr_redox_2 PF07992.14 OAG36324.1 - 1.8e-48 165.3 0.1 2.4e-48 164.9 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.26 OAG36324.1 - 4.6e-15 55.3 0.0 1.2e-14 54.0 0.0 1.7 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox PF00070.27 OAG36324.1 - 5.6e-14 52.5 1.3 2.6e-13 50.3 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.6 OAG36324.1 - 1.2e-05 25.1 0.0 3.2e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Reductase_C PF14759.6 OAG36324.1 - 1.8e-05 25.2 0.0 4.1e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Reductase C-terminal DUF1188 PF06690.11 OAG36324.1 - 0.00085 18.9 0.1 0.0013 18.3 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1188) NAD_binding_9 PF13454.6 OAG36324.1 - 0.007 16.4 0.2 6.9 6.6 0.0 3.4 4 0 0 4 4 4 1 FAD-NAD(P)-binding RPA43_OB PF17875.1 OAG36325.1 - 3.5e-32 111.6 0.1 3.5e-32 111.6 0.1 2.6 2 1 0 2 2 2 1 RPA43 OB domain in RNA Pol I SHS2_Rpb7-N PF03876.17 OAG36325.1 - 0.00021 21.6 0.0 0.00043 20.6 0.0 1.6 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 SRRM_C PF15230.6 OAG36325.1 - 2.5 8.7 7.3 1.1 9.9 0.2 2.9 2 0 0 2 2 2 0 Serine/arginine repetitive matrix protein C-terminus MFS_1 PF07690.16 OAG36326.1 - 1.1e-22 80.4 34.8 1.7e-13 50.2 13.9 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG36326.1 - 0.0017 17.3 7.0 0.0017 17.3 7.0 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 OAG36328.1 - 3.1e-33 115.1 27.0 4e-33 114.7 27.0 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG36328.1 - 3.3e-21 75.6 49.2 3.3e-21 75.6 49.2 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily Abhydrolase_3 PF07859.13 OAG36329.1 - 8.8e-46 156.4 0.0 1.1e-45 156.1 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 OAG36329.1 - 3.1e-08 32.9 0.0 8.4e-08 31.5 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family DUF2236 PF09995.9 OAG36330.1 - 2.5e-10 41.0 0.3 2.5e-10 41.0 0.3 1.4 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2236) DUF3425 PF11905.8 OAG36331.1 - 1.3e-10 41.3 0.2 2.4e-10 40.5 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 OAG36331.1 - 8.1e-05 22.7 1.8 0.00014 21.9 1.8 1.3 1 0 0 1 1 1 1 bZIP transcription factor ABC_tran_Xtn PF12848.7 OAG36331.1 - 0.12 12.4 1.2 0.22 11.6 1.2 1.4 1 0 0 1 1 1 0 ABC transporter CDC45 PF02724.14 OAG36332.1 - 0.024 13.0 1.9 0.033 12.5 1.9 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 OAG36332.1 - 0.046 12.0 2.6 0.065 11.5 2.6 1.2 1 0 0 1 1 1 0 Nop14-like family DNA_gyraseA_C PF03989.13 OAG36332.1 - 0.092 12.2 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 DNA gyrase C-terminal domain, beta-propeller CLTH PF10607.9 OAG36333.1 - 1.6e-26 92.9 0.0 2.8e-26 92.2 0.0 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.28 OAG36333.1 - 1.9e-25 89.3 0.9 3e-25 88.7 0.2 1.7 2 0 0 2 2 2 1 SPRY domain LisH PF08513.11 OAG36333.1 - 0.0002 21.2 0.7 0.00067 19.5 0.1 2.2 3 0 0 3 3 3 1 LisH Wzt_C PF14524.6 OAG36333.1 - 0.026 14.5 0.0 1.9 8.5 0.0 2.3 2 0 0 2 2 2 0 Wzt C-terminal domain Phospho_p8 PF10195.9 OAG36333.1 - 0.58 10.7 2.0 0.82 10.2 0.2 2.3 2 0 0 2 2 2 0 DNA-binding nuclear phosphoprotein p8 INO80_Ies4 PF08193.11 OAG36334.1 - 7.6e-70 235.6 19.4 7.6e-70 235.6 19.4 1.6 1 1 1 2 2 2 1 INO80 complex subunit Ies4 MCLC PF05934.11 OAG36334.1 - 0.66 8.6 6.0 0.15 10.8 2.6 1.5 2 0 0 2 2 2 0 Mid-1-related chloride channel (MCLC) Mei5 PF10376.9 OAG36335.1 - 0.00062 19.7 4.7 0.00086 19.2 3.1 2.1 2 1 0 2 2 2 1 Double-strand recombination repair protein OmpH PF03938.14 OAG36335.1 - 0.0079 16.5 0.5 0.013 15.8 0.5 1.3 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) Epimerase PF01370.21 OAG36336.1 - 1.7e-12 47.3 0.0 4.9e-12 45.8 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAG36336.1 - 6.7e-07 29.0 0.0 9.9e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 OAG36336.1 - 1.5e-05 24.3 0.0 0.00048 19.4 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.6 OAG36336.1 - 4.6e-05 23.4 0.0 9e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding F420_oxidored PF03807.17 OAG36336.1 - 0.033 14.8 0.0 0.11 13.1 0.0 2.0 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 3Beta_HSD PF01073.19 OAG36336.1 - 0.033 13.2 0.0 0.081 11.9 0.0 1.7 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Sacchrp_dh_NADP PF03435.18 OAG36336.1 - 0.057 13.7 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain adh_short PF00106.25 OAG36336.1 - 0.081 12.4 0.0 0.2 11.1 0.0 1.7 2 0 0 2 2 2 0 short chain dehydrogenase KR PF08659.10 OAG36336.1 - 0.11 12.3 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 KR domain Arf PF00025.21 OAG36337.1 - 3.9e-39 133.9 0.6 5.4e-24 84.6 0.7 3.0 2 1 0 2 2 2 2 ADP-ribosylation factor family G-alpha PF00503.20 OAG36337.1 - 4.6e-12 45.8 0.0 3e-06 26.6 0.0 2.8 1 1 0 2 2 2 2 G-protein alpha subunit Roc PF08477.13 OAG36337.1 - 2.1e-10 40.9 0.0 6.1e-10 39.4 0.0 1.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 OAG36337.1 - 1.3e-07 31.4 0.1 0.00051 19.7 0.1 2.9 2 1 0 2 2 2 2 Ras family SRPRB PF09439.10 OAG36337.1 - 1.3e-06 27.9 0.2 3.5e-05 23.3 0.1 2.5 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 OAG36337.1 - 3.7e-06 27.0 0.1 1.2e-05 25.4 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OAG36337.1 - 0.00012 21.7 0.1 0.07 12.7 0.0 2.1 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OAG36337.1 - 0.00062 19.2 0.0 0.0012 18.2 0.0 1.6 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 OAG36337.1 - 0.013 15.0 0.3 0.029 13.9 0.1 1.7 2 0 0 2 2 2 0 Ferrous iron transport protein B zf-C2H2_4 PF13894.6 OAG36338.1 - 0.7 10.9 12.1 6 8.0 0.5 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger Fungal_trans_2 PF11951.8 OAG36339.1 - 5.2e-47 160.5 4.9 6.4e-47 160.2 4.9 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG36339.1 - 1.2e-10 41.3 4.9 2e-10 40.6 4.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HZS_alpha PF18582.1 OAG36339.1 - 0.065 13.7 0.0 0.16 12.5 0.0 1.6 1 0 0 1 1 1 0 Hydrazine synthase alpha subunit middle domain Arrestin_N PF00339.29 OAG36340.1 - 5.9e-13 49.1 0.0 8.7e-09 35.6 0.0 3.1 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain Bul1_C PF04426.12 OAG36340.1 - 0.03 13.7 0.0 0.055 12.9 0.0 1.4 1 0 0 1 1 1 0 Bul1 C terminus RSN1_7TM PF02714.15 OAG36341.1 - 1.7e-80 270.3 23.8 2.6e-80 269.7 23.8 1.3 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 OAG36341.1 - 1.5e-38 132.0 2.5 1.5e-38 132.0 2.5 2.2 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 OAG36341.1 - 1.1e-23 84.4 0.1 1.7e-23 83.8 0.1 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 OAG36341.1 - 3.8e-20 71.8 0.1 9.3e-20 70.6 0.1 1.6 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter RRM_1 PF00076.22 OAG36341.1 - 0.13 12.1 0.0 0.52 10.2 0.0 2.0 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) adh_short PF00106.25 OAG36343.1 - 7.2e-36 123.5 0.0 9e-36 123.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG36343.1 - 6.3e-18 65.2 0.0 7.9e-18 64.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG36343.1 - 7.3e-06 26.0 0.0 1.2e-05 25.3 0.0 1.4 1 1 0 1 1 1 1 KR domain F420_oxidored PF03807.17 OAG36343.1 - 0.00018 22.0 0.0 0.00031 21.3 0.0 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 OAG36343.1 - 0.0023 18.0 0.0 0.004 17.2 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.15 OAG36343.1 - 0.0069 15.6 0.0 0.0095 15.1 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 OAG36343.1 - 0.012 15.1 0.1 0.038 13.5 0.0 1.8 2 0 0 2 2 2 0 NmrA-like family 2-Hacid_dh_C PF02826.19 OAG36343.1 - 0.07 12.5 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Epimerase PF01370.21 OAG36343.1 - 0.081 12.4 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 OAG36343.1 - 0.09 12.7 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding FTR PF01913.18 OAG36343.1 - 0.17 11.8 0.0 0.3 11.0 0.0 1.3 1 0 0 1 1 1 0 Formylmethanofuran-tetrahydromethanopterin formyltransferase Pyr_redox PF00070.27 OAG36343.1 - 0.19 12.3 0.3 0.7 10.5 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SLATT_fungal PF18142.1 OAG36344.1 - 5.3e-36 123.2 0.8 7.7e-36 122.7 0.8 1.2 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain Nucleo_P87 PF07267.11 OAG36344.1 - 0.0086 15.0 0.9 0.0094 14.9 0.9 1.1 1 0 0 1 1 1 1 Nucleopolyhedrovirus capsid protein P87 SAPS PF04499.15 OAG36344.1 - 0.11 11.3 3.3 0.12 11.1 3.3 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Menin PF05053.13 OAG36344.1 - 2.9 6.2 10.0 3.9 5.7 10.0 1.2 1 0 0 1 1 1 0 Menin BTB PF00651.31 OAG36345.1 - 2.3e-07 31.0 0.0 4.5e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain CENP-B_dimeris PF09026.10 OAG36345.1 - 0.0026 18.1 4.8 0.0091 16.4 3.4 2.2 2 0 0 2 2 2 1 Centromere protein B dimerisation domain RXT2_N PF08595.11 OAG36345.1 - 0.17 11.9 2.9 0.31 11.1 2.9 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF2457 PF10446.9 OAG36345.1 - 0.61 9.2 8.4 1 8.4 8.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NOA36 PF06524.12 OAG36345.1 - 2.8 7.2 6.3 4.7 6.5 6.3 1.3 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 OAG36345.1 - 3.4 5.7 7.9 4.6 5.2 7.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi Mto2_bdg PF12808.7 OAG36346.1 - 5e-20 71.5 30.9 1.6e-17 63.6 19.2 10.7 11 3 1 12 12 12 2 Micro-tubular organiser Mto1 C-term Mto2-binding region Cnn_1N PF07989.11 OAG36346.1 - 2.9e-19 69.0 10.4 2.9e-19 69.0 10.4 12.0 10 3 3 13 13 13 2 Centrosomin N-terminal motif 1 Cep57_MT_bd PF06657.13 OAG36346.1 - 0.0021 18.5 1.6 0.0021 18.5 1.6 10.2 9 2 3 12 12 12 1 Centrosome microtubule-binding domain of Cep57 MHC_II_beta PF00969.19 OAG36346.1 - 0.038 14.1 2.3 0.15 12.2 1.2 2.6 3 0 0 3 3 3 0 Class II histocompatibility antigen, beta domain DUF1664 PF07889.12 OAG36346.1 - 0.13 12.3 0.1 0.13 12.3 0.1 8.6 6 2 3 9 9 9 0 Protein of unknown function (DUF1664) DASH_Duo1 PF08651.10 OAG36346.1 - 1.6 8.6 13.1 1.7 8.5 0.1 5.1 5 1 1 6 6 6 0 DASH complex subunit Duo1 Sec7 PF01369.20 OAG36347.1 - 7.7e-24 84.4 0.0 1.6e-23 83.4 0.0 1.4 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.6 OAG36347.1 - 4.7e-17 62.5 0.0 1.5e-16 60.8 0.0 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain UNC-50 PF05216.13 OAG36348.1 - 3.5e-82 275.3 12.5 3.9e-82 275.1 12.5 1.0 1 0 0 1 1 1 1 UNC-50 family Glyco_hydro_44 PF12891.7 OAG36348.1 - 0.068 13.1 0.0 0.097 12.6 0.0 1.1 1 0 0 1 1 1 0 Glycoside hydrolase family 44 GFA PF04828.14 OAG36349.1 - 1.4e-21 76.7 0.7 2.3e-21 75.9 0.7 1.4 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme NOB1_Zn_bind PF08772.11 OAG36349.1 - 0.035 14.3 1.8 1.9 8.7 0.0 2.4 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like Auto_anti-p27 PF06677.12 OAG36349.1 - 0.1 12.8 0.1 0.1 12.8 0.1 2.0 3 0 0 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) NTP_transf_2 PF01909.23 OAG36350.1 - 0.068 13.5 0.0 0.18 12.1 0.0 1.7 1 0 0 1 1 1 0 Nucleotidyltransferase domain Glyco_transf_20 PF00982.21 OAG36351.1 - 1.6e-153 511.8 0.0 3.3e-153 510.8 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 OAG36351.1 - 1.4e-82 276.3 0.0 2.4e-82 275.6 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.12 OAG36351.1 - 0.0016 18.3 0.0 0.16 11.7 0.0 2.5 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase PP28 PF10252.9 OAG36352.1 - 1.3e-29 102.5 21.2 1.3e-29 102.5 21.2 3.2 3 0 0 3 3 3 2 Casein kinase substrate phosphoprotein PP28 Nop53 PF07767.11 OAG36352.1 - 4 6.7 57.0 5.2 6.4 15.9 2.0 1 1 1 2 2 2 0 Nop53 (60S ribosomal biogenesis) JCAD PF15351.6 OAG36352.1 - 5 4.8 30.7 6.5 4.4 30.7 1.0 1 0 0 1 1 1 0 Junctional protein associated with coronary artery disease DUF1917 PF08939.10 OAG36353.1 - 4.7e-66 223.4 0.0 1.3e-65 221.9 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF1917) HeLo PF14479.6 OAG36354.1 - 7.8e-25 87.9 1.1 1.5e-24 86.9 1.1 1.5 1 0 0 1 1 1 1 Prion-inhibition and propagation Pkinase PF00069.25 OAG36354.1 - 0.00051 19.5 0.0 0.0012 18.2 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain PfkB PF00294.24 OAG36355.1 - 3.5e-40 138.2 0.1 6.9e-40 137.2 0.1 1.5 1 1 0 1 1 1 1 pfkB family carbohydrate kinase XdhC_C PF13478.6 OAG36355.1 - 0.031 14.8 0.0 0.075 13.5 0.0 1.7 1 0 0 1 1 1 0 XdhC Rossmann domain Pkinase PF00069.25 OAG36356.1 - 1.3e-38 132.8 0.0 1.8e-38 132.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG36356.1 - 1.5e-18 67.0 0.0 2.1e-18 66.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 OAG36356.1 - 0.0097 15.5 0.0 0.039 13.6 0.0 1.9 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Polyketide_cyc2 PF10604.9 OAG36357.1 - 0.0066 16.7 0.2 0.015 15.6 0.2 1.6 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 OAG36357.1 - 0.0076 16.5 0.2 0.028 14.6 0.0 1.9 2 0 0 2 2 2 1 Polyketide cyclase / dehydrase and lipid transport Glyco_transf_20 PF00982.21 OAG36358.1 - 3.2e-149 497.6 0.0 1.9e-148 495.1 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase family 20 Glycos_transf_1 PF00534.20 OAG36358.1 - 9.3e-07 28.5 0.0 1.6e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 OAG36358.1 - 0.015 15.7 0.0 0.034 14.6 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferases group 1 DUF1624 PF07786.12 OAG36358.1 - 0.14 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1624) Pkinase PF00069.25 OAG36359.1 - 8.1e-18 64.7 0.0 5.8e-17 61.9 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG36359.1 - 6.1e-08 32.3 0.0 9.5e-08 31.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OAG36359.1 - 0.00047 20.2 0.0 0.00074 19.5 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OAG36359.1 - 0.0031 16.4 0.0 0.0057 15.5 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 OAG36359.1 - 0.17 11.5 0.0 0.27 10.8 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Oxysterol_BP PF01237.18 OAG36360.1 - 5.6e-120 400.6 0.0 1.1e-119 399.7 0.0 1.5 1 0 0 1 1 1 1 Oxysterol-binding protein PH_8 PF15409.6 OAG36360.1 - 5.2e-37 126.0 0.1 1.2e-36 124.8 0.1 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 OAG36360.1 - 3.3e-06 27.6 0.4 1.9e-05 25.1 0.0 2.5 2 0 0 2 2 2 1 PH domain Ino80_Iec3 PF14612.6 OAG36361.1 - 2e-67 228.3 0.7 2.9e-67 227.8 0.7 1.2 1 0 0 1 1 1 1 IEC3 subunit of the Ino80 complex, chromatin re-modelling RRM_1 PF00076.22 OAG36362.1 - 2.2e-19 69.0 0.0 2.9e-11 43.0 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 OAG36362.1 - 0.0065 16.4 0.0 0.023 14.7 0.0 1.8 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Btz PF09405.10 OAG36363.1 - 2.3e-20 73.2 1.8 2.3e-20 73.2 1.8 2.2 2 0 0 2 2 2 1 CASC3/Barentsz eIF4AIII binding N_BRCA1_IG PF16158.5 OAG36364.1 - 1.7e-28 99.3 0.0 8.4e-28 97.1 0.0 2.1 1 1 1 2 2 2 1 Ig-like domain from next to BRCA1 gene ZZ PF00569.17 OAG36364.1 - 7.4e-23 80.1 48.8 1.9e-08 34.0 5.5 4.4 4 0 0 4 4 4 4 Zinc finger, ZZ type C1_2 PF03107.16 OAG36364.1 - 0.0056 17.0 46.5 0.08 13.3 5.2 4.6 4 0 0 4 4 4 4 C1 domain IFRD PF05004.13 OAG36365.1 - 3e-73 246.6 13.9 4e-73 246.2 13.9 1.1 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) ADP_ribosyl_GH PF03747.14 OAG36365.1 - 0.00059 19.7 0.4 0.0012 18.7 0.4 1.5 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase Adaptin_N PF01602.20 OAG36365.1 - 0.0014 17.3 0.7 0.0023 16.6 0.7 1.4 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.6 OAG36365.1 - 0.068 13.6 1.8 1.4 9.4 0.1 2.8 2 0 0 2 2 2 0 HEAT repeats DUF4070 PF13282.6 OAG36365.1 - 0.1 12.7 0.0 0.25 11.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4070) PAP2_3 PF14378.6 OAG36366.1 - 1.3e-23 83.7 21.2 1.3e-23 83.7 21.2 3.4 3 1 0 3 3 3 1 PAP2 superfamily PAP2_C PF14360.6 OAG36366.1 - 0.0079 16.7 1.3 0.0079 16.7 1.3 3.5 4 1 0 4 4 4 1 PAP2 superfamily C-terminal Acetyltransf_2 PF00797.17 OAG36366.1 - 0.014 15.1 0.1 0.023 14.5 0.1 1.2 1 0 0 1 1 1 0 N-acetyltransferase Fungal_trans_2 PF11951.8 OAG36367.1 - 0.00014 20.8 0.2 0.00029 19.8 0.1 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Gpi1 PF05024.15 OAG36369.1 - 5.5e-75 251.6 8.8 9.8e-75 250.7 8.8 1.4 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) DUF155 PF02582.14 OAG36371.1 - 1.2e-46 159.1 0.0 1.7e-46 158.5 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Clathrin PF00637.20 OAG36372.1 - 4.9e-17 62.1 1.3 6.5e-15 55.3 0.6 2.6 2 1 0 2 2 2 2 Region in Clathrin and VPS WD40_like PF17005.5 OAG36372.1 - 0.0041 16.5 0.0 0.0069 15.7 0.0 1.3 1 0 0 1 1 1 1 WD40-like domain zf-RING_5 PF14634.6 OAG36372.1 - 0.0068 16.3 1.3 0.015 15.2 1.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Vps39_1 PF10366.9 OAG36372.1 - 0.11 12.8 0.2 0.27 11.5 0.2 1.6 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 1 Tfb2 PF03849.14 OAG36373.1 - 7.4e-121 403.4 0.0 1.2e-120 402.8 0.0 1.2 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 OAG36373.1 - 5.8e-22 77.9 0.2 1.4e-21 76.7 0.2 1.7 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 OAG36373.1 - 1.2e-05 25.5 0.1 2.8e-05 24.3 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain 4HBT PF03061.22 OAG36374.1 - 6e-12 45.8 0.0 9.2e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.6 OAG36374.1 - 0.023 14.8 0.0 0.032 14.4 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4442) Actin PF00022.19 OAG36375.1 - 4.9e-89 298.8 0.0 4.7e-88 295.5 0.0 1.9 1 1 0 1 1 1 1 Actin PilM_2 PF11104.8 OAG36375.1 - 0.13 11.3 0.0 3.8 6.5 0.0 2.1 2 0 0 2 2 2 0 Type IV pilus assembly protein PilM; MreB_Mbl PF06723.13 OAG36375.1 - 0.18 10.6 0.0 0.34 9.7 0.0 1.4 1 0 0 1 1 1 0 MreB/Mbl protein Astro_capsid_p PF12226.8 OAG36376.1 - 8.4 5.4 6.2 12 4.9 6.2 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Cupin_1 PF00190.22 OAG36377.1 - 1.3e-20 73.5 1.2 2.2e-20 72.8 1.2 1.2 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 OAG36377.1 - 1.1e-05 25.0 0.0 3.3e-05 23.5 0.0 1.8 2 0 0 2 2 2 1 Cupin domain ILVD_EDD PF00920.21 OAG36378.1 - 3.4e-208 692.5 1.5 3.9e-208 692.3 1.5 1.0 1 0 0 1 1 1 1 Dehydratase family Fungal_trans_2 PF11951.8 OAG36379.1 - 0.0033 16.3 0.1 0.0045 15.9 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF2415 PF10313.9 OAG36379.1 - 0.05 13.5 0.0 0.098 12.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein domain (DUF2415) Ferritin_2 PF13668.6 OAG36380.1 - 4.9e-37 127.2 0.4 4.9e-37 127.2 0.4 2.4 2 1 0 2 2 2 1 Ferritin-like domain FtsH_ext PF06480.15 OAG36380.1 - 0.02 15.2 5.3 0.33 11.3 3.5 2.6 2 0 0 2 2 2 0 FtsH Extracellular Dicty_REP PF05086.12 OAG36380.1 - 1.4 6.8 12.4 2 6.3 12.4 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein GRAM PF02893.20 OAG36382.1 - 3.4e-31 107.5 2.6 8.4e-21 74.0 0.0 3.4 3 0 0 3 3 3 3 GRAM domain Glyco_transf_28 PF03033.20 OAG36382.1 - 7e-29 100.6 0.0 1.4e-28 99.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain PH PF00169.29 OAG36382.1 - 2.4e-14 53.7 0.6 4e-12 46.6 0.4 2.5 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 OAG36382.1 - 1.6e-06 28.5 1.0 4.1e-06 27.2 1.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.6 OAG36382.1 - 0.00017 21.6 0.1 0.00045 20.3 0.1 1.6 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 OAG36382.1 - 0.011 16.0 0.3 0.041 14.2 0.2 2.0 2 0 0 2 2 2 0 Pleckstrin homology domain UDPGT PF00201.18 OAG36382.1 - 0.044 12.6 0.0 0.074 11.8 0.0 1.3 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_hydro_2_C PF02836.17 OAG36383.1 - 7.1e-107 357.0 0.0 9.5e-107 356.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.17 OAG36383.1 - 8.5e-61 205.6 0.0 1.3e-60 205.0 0.0 1.3 1 0 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.18 OAG36383.1 - 4.1e-44 150.5 0.4 2.4e-43 147.9 0.3 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain DUF4981 PF16353.5 OAG36383.1 - 4.5e-18 65.5 0.0 1.7e-17 63.7 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function(DUF4981) Glyco_hydro_2 PF00703.21 OAG36383.1 - 8.4e-15 55.4 0.0 1.7e-14 54.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Fungal_trans PF04082.18 OAG36384.1 - 4.8e-14 52.0 0.0 9.8e-14 51.0 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG36384.1 - 0.0011 19.0 7.6 0.0011 19.0 7.6 2.5 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldo_ket_red PF00248.21 OAG36386.1 - 9.5e-64 215.4 0.0 1.1e-63 215.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Cupin_2 PF07883.11 OAG36387.1 - 2.8e-11 43.0 0.0 4.4e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 OAG36387.1 - 0.0032 17.1 0.0 0.0055 16.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF861) MannoseP_isomer PF01050.18 OAG36387.1 - 0.042 13.7 0.0 0.058 13.3 0.0 1.1 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase Sulfatase PF00884.23 OAG36388.1 - 1.8e-59 201.7 0.0 2.7e-56 191.3 0.0 2.1 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 OAG36388.1 - 0.0014 18.3 0.0 0.0021 17.7 0.0 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 OAG36388.1 - 0.005 15.5 0.0 0.0081 14.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) DUF4994 PF16385.5 OAG36388.1 - 0.019 14.9 0.0 0.048 13.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function Sulfatase_C PF14707.6 OAG36388.1 - 0.071 13.9 0.1 0.61 10.8 0.1 2.2 1 1 0 1 1 1 0 C-terminal region of aryl-sulfatase Pap_E4 PF02711.14 OAG36390.1 - 1.5 9.9 7.7 14 6.7 7.8 2.4 3 0 0 3 3 3 0 E4 protein FAA_hydrolase PF01557.18 OAG36391.1 - 1e-51 175.7 0.0 1.3e-51 175.4 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family DUF3500 PF12006.8 OAG36392.1 - 6.2e-113 377.2 0.0 7.4e-113 376.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3500) DUF4185 PF13810.6 OAG36393.1 - 6.2e-15 55.2 4.0 3.6e-14 52.7 2.5 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4185) MFS_1 PF07690.16 OAG36394.1 - 6.4e-25 87.8 45.7 6.1e-17 61.6 22.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 OAG36394.1 - 2.4e-06 26.4 21.7 0.00061 18.5 8.3 2.6 1 1 2 3 3 3 2 MFS/sugar transport protein eIF-1a PF01176.19 OAG36395.1 - 1.6e-17 63.1 0.0 2.2e-17 62.6 0.0 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 CSD2 PF17876.1 OAG36395.1 - 0.091 12.9 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Cold shock domain ALG3 PF05208.13 OAG36396.1 - 5.3e-121 404.4 8.0 6.6e-121 404.1 8.0 1.0 1 0 0 1 1 1 1 ALG3 protein FMN_dh PF01070.18 OAG36397.1 - 1.9e-124 415.2 0.0 2.2e-124 415.0 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 OAG36397.1 - 1.7e-07 30.6 0.0 3.1e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 OAG36397.1 - 8.5e-06 25.1 0.0 2e-05 23.9 0.0 1.7 1 1 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.15 OAG36397.1 - 5.1e-05 22.8 0.6 8e-05 22.2 0.6 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.21 OAG36397.1 - 0.00032 20.2 0.0 0.002 17.7 0.0 2.0 1 1 1 2 2 2 1 Histidine biosynthesis protein ThiG PF05690.14 OAG36397.1 - 0.035 13.4 0.3 0.96 8.7 0.0 2.2 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG DHO_dh PF01180.21 OAG36397.1 - 0.26 10.5 0.0 0.4 9.8 0.0 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase zf-C2H2_jaz PF12171.8 OAG36398.1 - 8.3e-08 32.3 20.2 0.0057 16.9 0.1 5.7 6 0 0 6 6 6 4 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 OAG36398.1 - 1.1e-05 25.6 31.7 0.012 16.1 0.7 6.1 6 0 0 6 6 6 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAG36398.1 - 5.3e-05 23.7 30.3 0.92 10.5 0.4 6.3 6 0 0 6 6 6 5 C2H2-type zinc finger zf-met PF12874.7 OAG36398.1 - 0.0017 18.7 24.1 0.12 12.8 0.1 5.8 6 0 0 6 6 6 3 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 OAG36398.1 - 0.59 10.2 0.1 0.59 10.2 0.1 3.6 4 0 0 4 4 4 0 C2H2-type zinc finger Rad50_zn_hook PF04423.14 OAG36398.1 - 0.78 9.6 5.1 0.6 10.0 0.2 2.9 2 1 1 3 3 3 0 Rad50 zinc hook motif PLDc_2 PF13091.6 OAG36399.1 - 5.9e-17 61.8 0.0 5.6e-06 26.3 0.0 3.9 3 1 0 3 3 3 3 PLD-like domain PLDc PF00614.22 OAG36399.1 - 3.6e-14 52.3 1.2 9.1e-06 25.6 0.1 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif Cyanate_lyase PF02560.14 OAG36400.1 - 2e-31 107.7 0.0 3.4e-31 106.9 0.0 1.4 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain HTH_3 PF01381.22 OAG36400.1 - 0.014 15.4 0.0 0.022 14.8 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix Caps_synth PF05704.12 OAG36401.1 - 0.56 9.5 2.4 0.73 9.2 2.4 1.1 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein RRM_1 PF00076.22 OAG36404.1 - 2.5e-09 36.8 0.1 0.004 17.0 0.0 2.9 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA PF00004.29 OAG36405.1 - 8.5e-08 32.7 0.1 7.5e-07 29.6 0.1 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OAG36405.1 - 0.00041 20.6 0.0 0.0059 16.9 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OAG36405.1 - 0.0016 18.9 0.2 0.0054 17.1 0.2 1.9 1 1 0 1 1 1 1 AAA ATPase domain Rad17 PF03215.15 OAG36405.1 - 0.0036 17.2 0.2 0.016 15.1 0.0 2.1 3 0 0 3 3 3 1 Rad17 P-loop domain TIP49 PF06068.13 OAG36405.1 - 0.0059 15.9 0.1 0.017 14.4 0.0 1.7 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_18 PF13238.6 OAG36405.1 - 0.0068 17.0 0.0 0.02 15.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 OAG36405.1 - 0.066 13.0 0.0 0.066 13.0 0.0 3.4 2 2 1 3 3 3 0 AAA domain AAA_5 PF07728.14 OAG36405.1 - 0.069 13.1 0.0 0.3 11.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Ntox21 PF15526.6 OAG36405.1 - 0.08 13.3 0.1 0.24 11.7 0.1 1.8 1 0 0 1 1 1 0 Novel toxin 21 NTPase_1 PF03266.15 OAG36405.1 - 0.09 12.7 0.0 0.23 11.4 0.0 1.7 2 0 0 2 2 2 0 NTPase T2SSE PF00437.20 OAG36405.1 - 0.12 11.4 0.0 0.24 10.4 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein RuvB_N PF05496.12 OAG36405.1 - 0.13 12.0 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 OAG36405.1 - 0.14 11.5 0.0 0.27 10.6 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 OAG36405.1 - 0.16 11.5 0.3 0.47 9.9 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region Utp8 PF10395.9 OAG36406.1 - 0.00029 19.5 0.0 0.0051 15.4 0.0 2.6 2 1 0 2 2 2 1 Utp8 family NTP_transf_3 PF12804.7 OAG36406.1 - 0.23 11.8 1.3 1.9 8.8 0.6 2.5 2 1 0 2 2 2 0 MobA-like NTP transferase domain SAM_2 PF07647.17 OAG36407.1 - 6.7e-17 61.4 0.0 1e-16 60.8 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 OAG36407.1 - 1.5e-13 51.0 0.0 2.4e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.23 OAG36407.1 - 1.7e-08 35.0 0.0 3.4e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SAM_4 PF18017.1 OAG36407.1 - 0.06 13.3 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) EnY2 PF10163.9 OAG36408.1 - 7.8e-07 29.4 0.0 1.3e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 Transcription factor e(y)2 FSA_C PF10479.9 OAG36408.1 - 0.11 10.7 0.1 0.13 10.4 0.1 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus AAA PF00004.29 OAG36409.1 - 3.8e-97 321.8 0.1 3.7e-47 160.0 0.0 2.8 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OAG36409.1 - 4.2e-25 87.3 3.7 7e-13 48.2 0.3 3.1 2 1 0 2 2 2 2 AAA+ lid domain CDC48_N PF02359.18 OAG36409.1 - 5.1e-19 68.2 0.4 1.5e-18 66.8 0.4 1.9 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_2 PF07724.14 OAG36409.1 - 3.1e-14 53.4 0.0 1.1e-07 32.2 0.0 2.9 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 OAG36409.1 - 3.9e-14 52.7 0.0 6.8e-06 25.9 0.0 3.1 3 1 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 OAG36409.1 - 4.5e-13 49.6 0.1 2.2e-05 24.6 0.0 3.6 4 0 0 4 4 2 2 AAA domain AAA_16 PF13191.6 OAG36409.1 - 1.4e-12 48.3 0.0 0.00019 21.9 0.0 4.9 3 2 1 4 4 4 2 AAA ATPase domain AAA_5 PF07728.14 OAG36409.1 - 3.6e-11 43.2 0.5 2e-05 24.6 0.1 3.7 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 OAG36409.1 - 2.9e-09 37.3 0.4 0.032 14.5 0.0 4.4 2 2 1 3 3 3 2 AAA domain TIP49 PF06068.13 OAG36409.1 - 3.2e-09 36.5 0.0 0.0013 18.0 0.0 2.8 2 0 0 2 2 2 2 TIP49 P-loop domain CDC48_2 PF02933.17 OAG36409.1 - 5.7e-08 32.4 0.0 1.3e-07 31.3 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 Mg_chelatase PF01078.21 OAG36409.1 - 8.6e-08 31.8 0.3 0.0071 15.7 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 OAG36409.1 - 5.5e-07 30.2 0.0 0.03 14.9 0.0 2.9 3 0 0 3 3 2 2 AAA domain IstB_IS21 PF01695.17 OAG36409.1 - 5.8e-07 29.4 0.0 0.02 14.6 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein RNA_helicase PF00910.22 OAG36409.1 - 6.3e-07 29.8 0.0 0.03 14.7 0.0 2.9 2 0 0 2 2 2 2 RNA helicase Vps4_C PF09336.10 OAG36409.1 - 7.6e-07 29.0 0.1 1.3e-05 25.1 0.0 2.6 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_25 PF13481.6 OAG36409.1 - 1.1e-06 28.3 4.4 0.21 11.2 0.1 4.7 3 2 1 5 5 5 2 AAA domain AAA_14 PF13173.6 OAG36409.1 - 1.6e-06 28.2 0.0 0.017 15.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain ATPase PF06745.13 OAG36409.1 - 1.7e-06 27.6 0.9 0.53 9.6 0.0 3.7 4 0 0 4 4 3 2 KaiC AAA_7 PF12775.7 OAG36409.1 - 4.9e-06 26.2 0.1 0.033 13.7 0.0 3.1 2 2 0 2 2 2 2 P-loop containing dynein motor region AAA_24 PF13479.6 OAG36409.1 - 6.9e-06 25.9 0.0 0.14 11.9 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_28 PF13521.6 OAG36409.1 - 7.2e-06 26.3 0.1 0.19 12.0 0.0 3.4 3 0 0 3 3 3 2 AAA domain Parvo_NS1 PF01057.17 OAG36409.1 - 1.6e-05 24.1 0.1 0.053 12.6 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 DUF815 PF05673.13 OAG36409.1 - 2.8e-05 23.4 0.0 0.022 14.0 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Bac_DnaA PF00308.18 OAG36409.1 - 3.4e-05 23.8 0.0 0.11 12.3 0.0 2.8 3 0 0 3 3 2 2 Bacterial dnaA protein Sigma54_activat PF00158.26 OAG36409.1 - 4.2e-05 23.3 0.1 0.44 10.2 0.0 3.3 2 2 0 2 2 2 2 Sigma-54 interaction domain ABC_tran PF00005.27 OAG36409.1 - 7.1e-05 23.3 0.0 0.28 11.7 0.0 3.5 2 1 0 2 2 2 1 ABC transporter AAA_17 PF13207.6 OAG36409.1 - 0.00012 22.5 0.1 0.62 10.5 0.0 3.5 4 0 0 4 4 2 1 AAA domain AAA_11 PF13086.6 OAG36409.1 - 0.00018 21.4 0.0 0.67 9.7 0.0 2.8 2 1 0 2 2 2 2 AAA domain TsaE PF02367.17 OAG36409.1 - 0.00024 21.1 0.0 0.52 10.3 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE PhoH PF02562.16 OAG36409.1 - 0.00025 20.5 0.4 0.7 9.3 0.0 2.6 2 0 0 2 2 2 2 PhoH-like protein ResIII PF04851.15 OAG36409.1 - 0.0003 20.8 0.0 0.081 12.9 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit NACHT PF05729.12 OAG36409.1 - 0.00033 20.6 0.1 0.18 11.7 0.0 2.9 3 0 0 3 3 3 1 NACHT domain AAA_3 PF07726.11 OAG36409.1 - 0.00041 20.2 0.0 1.1 9.1 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 OAG36409.1 - 0.00073 19.5 0.0 2.4 8.0 0.0 3.6 3 1 0 3 3 3 1 ATPase domain predominantly from Archaea AAA_30 PF13604.6 OAG36409.1 - 0.0012 18.6 0.4 1.2 8.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.9 OAG36409.1 - 0.0018 17.6 0.0 1.5 8.0 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) Zeta_toxin PF06414.12 OAG36409.1 - 0.0036 16.6 1.3 6.2 6.0 0.0 3.7 4 0 0 4 4 3 0 Zeta toxin Viral_helicase1 PF01443.18 OAG36409.1 - 0.004 16.9 0.0 0.37 10.5 0.0 2.7 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.22 OAG36409.1 - 0.0076 15.5 0.0 1.5 8.0 0.0 2.6 2 0 0 2 2 2 1 NB-ARC domain UFD1 PF03152.14 OAG36409.1 - 0.0088 15.5 0.0 0.068 12.6 0.0 2.0 1 1 1 2 2 2 1 Ubiquitin fusion degradation protein UFD1 NTPase_1 PF03266.15 OAG36409.1 - 0.011 15.7 0.9 2.6 7.9 0.0 3.9 4 0 0 4 4 3 0 NTPase KAP_NTPase PF07693.14 OAG36409.1 - 0.012 14.8 0.2 0.95 8.6 0.0 3.0 2 2 0 3 3 3 0 KAP family P-loop domain AAA_19 PF13245.6 OAG36409.1 - 0.015 15.6 3.4 6.1 7.2 0.0 3.9 4 1 0 5 5 3 0 AAA domain IPT PF01745.16 OAG36409.1 - 0.018 14.4 0.0 2.4 7.5 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase Sigma54_activ_2 PF14532.6 OAG36409.1 - 0.028 14.5 0.0 3.9 7.6 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain Zot PF05707.12 OAG36409.1 - 0.047 13.3 0.0 2.1 8.0 0.0 3.0 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) TniB PF05621.11 OAG36409.1 - 0.056 12.9 0.1 24 4.3 0.0 3.6 4 0 0 4 4 4 0 Bacterial TniB protein Cytidylate_kin PF02224.18 OAG36409.1 - 0.061 13.1 0.0 10 5.8 0.0 2.7 2 0 0 2 2 2 0 Cytidylate kinase AAA_6 PF12774.7 OAG36409.1 - 0.067 12.1 0.3 9.3 5.1 0.0 2.5 3 0 0 3 3 2 0 Hydrolytic ATP binding site of dynein motor region AFG1_ATPase PF03969.16 OAG36409.1 - 0.091 11.6 0.0 14 4.5 0.0 2.4 2 0 0 2 2 2 0 AFG1-like ATPase eIF-1a PF01176.19 OAG36409.1 - 0.24 11.2 1.0 1.7 8.5 0.4 2.6 1 1 1 2 2 2 0 Translation initiation factor 1A / IF-1 Kei1 PF08552.11 OAG36410.1 - 1.7e-64 217.3 3.3 2e-64 217.0 3.3 1.1 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 ADH_N PF08240.12 OAG36411.1 - 4e-27 94.3 0.0 2.1e-26 91.9 0.0 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG36411.1 - 2.4e-19 69.6 0.0 4.5e-19 68.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAG36411.1 - 4.8e-06 27.7 0.0 1.4e-05 26.2 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 OAG36411.1 - 8.1e-06 25.5 0.1 0.00011 21.7 0.1 2.3 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 OAG36411.1 - 0.0099 15.2 0.3 0.038 13.3 0.1 1.9 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.14 OAG36411.1 - 0.063 12.5 0.1 0.098 11.9 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAG36411.1 - 0.12 12.9 0.2 0.28 11.8 0.2 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG36411.1 - 0.17 11.1 0.0 0.3 10.3 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_2 PF00891.18 OAG36411.1 - 0.18 11.1 0.1 0.31 10.3 0.1 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Pantoate_transf PF02548.15 OAG36412.1 - 1.7e-50 171.8 0.9 7.2e-50 169.8 0.9 1.7 1 1 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 OAG36412.1 - 0.0023 17.5 0.3 0.0086 15.5 0.0 1.9 1 1 0 1 1 1 1 Phosphoenolpyruvate phosphomutase PAP2_3 PF14378.6 OAG36413.1 - 8.8e-29 100.5 13.3 1.9e-13 50.6 0.4 3.2 3 0 0 3 3 3 3 PAP2 superfamily PAP2 PF01569.21 OAG36413.1 - 0.43 10.3 6.9 0.045 13.5 0.8 2.3 2 1 0 2 2 2 0 PAP2 superfamily PAP2_C PF14360.6 OAG36413.1 - 0.77 10.3 4.9 0.33 11.5 0.3 2.4 2 0 0 2 2 2 0 PAP2 superfamily C-terminal HET PF06985.11 OAG36414.1 - 2.8e-23 82.9 0.0 4.5e-23 82.2 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) GHMP_kinases_N PF00288.26 OAG36415.1 - 1e-16 60.9 3.1 2.7e-16 59.6 3.1 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 OAG36415.1 - 4.8e-07 30.1 0.1 1.6e-06 28.4 0.0 1.9 2 0 0 2 2 2 1 GHMP kinases C terminal SH3_15 PF18346.1 OAG36415.1 - 0.0047 17.2 0.0 0.013 15.8 0.0 1.8 1 0 0 1 1 1 1 Mind bomb SH3 repeat domain Rad60-SLD_2 PF13881.6 OAG36416.1 - 1.2e-09 38.3 0.1 3.5e-09 36.8 0.1 1.9 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 OAG36416.1 - 0.0035 17.9 0.0 0.008 16.7 0.0 1.6 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain UMP1 PF05348.11 OAG36417.1 - 6e-35 120.0 0.0 7.9e-35 119.6 0.0 1.2 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 Thump_like PF18096.1 OAG36417.1 - 0.13 12.2 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 THUMP domain-like AAA PF00004.29 OAG36420.1 - 8.9e-16 58.5 0.0 1.6e-15 57.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OAG36420.1 - 0.00054 20.3 0.5 0.0027 18.0 0.1 2.3 2 1 1 3 3 3 1 AAA domain AAA_16 PF13191.6 OAG36420.1 - 0.0027 18.1 0.1 0.013 15.9 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain Zot PF05707.12 OAG36420.1 - 0.026 14.2 0.1 0.42 10.2 0.0 2.2 1 1 0 2 2 2 0 Zonular occludens toxin (Zot) AAA_19 PF13245.6 OAG36420.1 - 0.039 14.3 0.3 0.086 13.2 0.3 1.5 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 OAG36420.1 - 0.078 13.0 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 OAG36420.1 - 0.089 12.5 0.2 0.18 11.5 0.2 1.4 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.14 OAG36420.1 - 0.1 12.7 0.0 0.25 11.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) ATPase PF06745.13 OAG36420.1 - 0.16 11.3 0.1 0.3 10.4 0.1 1.4 1 0 0 1 1 1 0 KaiC Goodbye PF17109.5 OAG36421.1 - 0.015 15.8 0.0 0.12 12.8 0.0 2.4 2 0 0 2 2 2 0 fungal STAND N-terminal Goodbye domain NACHT_N PF17100.5 OAG36421.1 - 0.027 14.4 0.7 1.2 8.9 0.7 2.3 1 1 0 1 1 1 0 N-terminal domain of NWD NACHT-NTPase Allexi_40kDa PF05549.11 OAG36421.1 - 0.11 12.0 0.0 2 7.9 0.0 2.2 2 0 0 2 2 2 0 Allexivirus 40kDa protein Herpes_UL55 PF04537.12 OAG36422.1 - 0.089 12.8 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus UL55 protein PRK PF00485.18 OAG36423.1 - 1.2e-56 191.6 0.0 1.8e-56 191.0 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.6 OAG36423.1 - 4.5e-39 134.1 0.0 7.3e-39 133.4 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AAA_18 PF13238.6 OAG36423.1 - 2.4e-06 28.1 0.0 5.4e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain CPT PF07931.12 OAG36423.1 - 0.00014 21.8 0.0 0.00034 20.5 0.0 1.7 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein Zeta_toxin PF06414.12 OAG36423.1 - 0.00081 18.7 0.0 0.0022 17.3 0.0 1.7 2 0 0 2 2 2 1 Zeta toxin AAA_33 PF13671.6 OAG36423.1 - 0.0013 18.9 0.0 0.0061 16.7 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 OAG36423.1 - 0.004 17.6 0.3 0.1 13.0 0.3 2.5 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.13 OAG36423.1 - 0.075 12.2 0.0 0.17 11.1 0.0 1.5 1 0 0 1 1 1 0 TIP49 P-loop domain NB-ARC PF00931.22 OAG36423.1 - 0.081 12.1 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA PF00004.29 OAG36423.1 - 0.088 13.2 0.0 0.45 10.9 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Cytidylate_kin PF02224.18 OAG36423.1 - 0.1 12.3 0.2 2.3 7.9 0.0 2.3 1 1 1 2 2 2 0 Cytidylate kinase MobB PF03205.14 OAG36423.1 - 0.11 12.4 0.1 0.29 11.0 0.1 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.27 OAG36423.1 - 0.57 10.7 2.0 0.92 10.0 0.1 2.1 2 1 0 2 2 2 0 ABC transporter RNase_T PF00929.24 OAG36424.1 - 4e-18 66.5 0.0 8.4e-18 65.4 0.0 1.6 1 0 0 1 1 1 1 Exonuclease RNase_H2_suC PF08615.11 OAG36424.1 - 5.2e-09 36.4 0.1 8.6e-09 35.7 0.1 1.4 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) DUF4385 PF14328.6 OAG36425.1 - 9.4e-53 178.2 0.3 1.1e-52 178.0 0.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4385) TSC22 PF01166.18 OAG36426.1 - 0.055 13.8 1.3 0.34 11.2 0.2 2.2 1 1 1 2 2 2 0 TSC-22/dip/bun family bZIP_1 PF00170.21 OAG36426.1 - 0.21 11.7 11.8 3.6 7.8 10.8 2.5 1 1 1 2 2 2 0 bZIP transcription factor Hfx_Cass5 PF18287.1 OAG36426.1 - 0.44 10.8 5.0 0.31 11.3 1.3 2.5 2 1 1 3 3 3 0 Integron Cassette Protein Hfx_Cass5 GIT_CC PF16559.5 OAG36426.1 - 0.6 10.0 2.7 1.2 9.1 2.7 1.4 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor adh_short_C2 PF13561.6 OAG36427.1 - 6.9e-52 176.3 0.1 1.6e-51 175.1 0.1 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG36427.1 - 1.1e-42 145.7 0.1 2e-42 144.9 0.1 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG36427.1 - 1.4e-05 25.0 0.1 3.2e-05 23.9 0.1 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG36427.1 - 4.3e-05 23.1 0.0 0.00042 19.9 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 OAG36427.1 - 0.058 12.7 0.0 0.17 11.2 0.0 1.8 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain adh_short_C2 PF13561.6 OAG36428.1 - 6e-54 183.1 1.9 4.2e-37 127.9 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG36428.1 - 1.3e-47 161.8 1.8 6.6e-29 100.8 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 OAG36428.1 - 5.1e-10 39.6 2.3 1.5e-07 31.5 1.6 2.3 2 0 0 2 2 2 2 KR domain Methyltransf_25 PF13649.6 OAG36428.1 - 0.0016 19.1 0.1 0.0033 18.1 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Polysacc_synt_2 PF02719.15 OAG36428.1 - 0.0089 15.2 0.1 0.017 14.2 0.1 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 OAG36428.1 - 0.082 12.4 0.1 0.9 8.9 0.3 2.2 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family CpcD PF01383.21 OAG36428.1 - 0.089 13.1 0.0 0.25 11.7 0.0 1.8 1 0 0 1 1 1 0 CpcD/allophycocyanin linker domain 2-Hacid_dh_C PF02826.19 OAG36428.1 - 0.12 11.7 0.2 0.2 11.0 0.2 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 OAG36428.1 - 0.12 12.2 0.6 0.2 11.6 0.6 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_12 PF08242.12 OAG36428.1 - 0.15 12.9 0.0 0.3 11.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain SdpA PF17418.2 OAG36428.1 - 0.16 11.8 0.0 3.8 7.4 0.1 2.1 2 0 0 2 2 2 0 Sporulation delaying protein SdpA CAP_N PF01213.19 OAG36428.1 - 2.5 7.5 4.3 3.7 7.0 4.3 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal ABM PF03992.16 OAG36429.1 - 0.038 14.1 0.5 2.7 8.2 0.1 2.9 2 2 0 2 2 2 0 Antibiotic biosynthesis monooxygenase MFS_1 PF07690.16 OAG36431.1 - 1.7e-44 152.2 33.0 1.7e-44 152.2 33.0 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG36431.1 - 1.1e-11 44.3 10.4 1.1e-11 44.3 10.4 2.2 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 OAG36431.1 - 1.5e-08 33.5 2.5 2.7e-08 32.7 2.5 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DcpS PF05652.12 OAG36432.1 - 2.3e-33 115.1 0.0 3.6e-33 114.5 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal DcpS_C PF11969.8 OAG36432.1 - 1.2e-26 93.4 0.1 1.9e-26 92.8 0.1 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HTH_50 PF18024.1 OAG36433.1 - 0.15 11.7 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Metallophos PF00149.28 OAG36434.1 - 0.0067 16.9 0.0 0.016 15.7 0.0 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF3458_C PF17432.2 OAG36434.1 - 0.17 11.3 0.0 0.27 10.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3458_C) ARM repeats Methyltransf_2 PF00891.18 OAG36435.1 - 6.6e-24 84.4 1.9 9.5e-24 83.9 0.4 2.0 2 1 0 2 2 2 1 O-methyltransferase domain Methyltransf_PK PF05891.12 OAG36435.1 - 0.013 15.0 0.0 0.021 14.3 0.0 1.2 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Glyco_hydro_16 PF00722.21 OAG36436.1 - 2.2e-43 147.8 0.5 3.6e-43 147.1 0.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 FAD_binding_3 PF01494.19 OAG36437.1 - 5.7e-47 160.6 0.0 7.4e-47 160.3 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 OAG36437.1 - 7.1e-05 22.2 0.0 0.0002 20.7 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG36437.1 - 0.00037 20.7 0.0 0.00086 19.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 OAG36437.1 - 0.00047 19.0 0.0 0.0016 17.2 0.0 1.8 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 OAG36437.1 - 0.00055 19.3 0.0 0.0047 16.2 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAG36437.1 - 0.0015 18.2 0.3 0.036 13.6 0.0 2.3 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OAG36437.1 - 0.0053 15.9 0.1 0.16 11.0 0.0 2.1 1 1 1 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 OAG36437.1 - 0.028 13.5 0.0 0.067 12.2 0.0 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein Amino_oxidase PF01593.24 OAG36437.1 - 0.063 12.6 0.2 12 5.0 0.1 2.7 2 1 0 3 3 3 0 Flavin containing amine oxidoreductase Thi4 PF01946.17 OAG36437.1 - 0.083 12.1 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Sulfotransfer_4 PF17784.1 OAG36438.1 - 6e-63 212.5 0.0 7.1e-63 212.3 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OAG36438.1 - 8.3e-08 32.9 0.5 5.7e-07 30.1 0.0 2.1 1 1 1 2 2 2 1 Sulfotransferase family Alk_phosphatase PF00245.20 OAG36439.1 - 5.5e-100 335.2 0.0 9.5e-100 334.4 0.0 1.4 1 1 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 OAG36439.1 - 0.00015 21.2 0.1 0.00029 20.3 0.1 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily DUF3545 PF12065.8 OAG36439.1 - 0.12 12.4 0.0 0.36 10.9 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3545) WD40 PF00400.32 OAG36441.1 - 2.9e-10 40.6 16.9 2.4e-05 25.0 0.1 5.8 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG36441.1 - 0.0021 18.3 0.0 2.9 8.2 0.0 3.2 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain ABC_membrane PF00664.23 OAG36442.1 - 3.6e-34 118.7 8.8 3.6e-34 118.7 8.8 2.0 2 0 0 2 2 2 1 ABC transporter transmembrane region ABC_tran PF00005.27 OAG36442.1 - 2.8e-32 112.1 0.0 6.6e-32 110.9 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 OAG36442.1 - 3.9e-06 26.5 1.6 0.0001 21.8 0.1 2.4 2 1 1 3 3 3 1 RecF/RecN/SMC N terminal domain AA_permease_2 PF13520.6 OAG36442.1 - 0.00073 18.5 2.3 0.00073 18.5 2.3 2.5 4 0 0 4 4 4 1 Amino acid permease AAA_16 PF13191.6 OAG36442.1 - 0.004 17.5 0.8 0.019 15.4 0.8 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 OAG36442.1 - 0.031 14.0 0.0 0.1 12.3 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 OAG36442.1 - 0.045 13.7 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_22 PF13401.6 OAG36442.1 - 0.088 13.1 0.1 0.24 11.7 0.1 1.8 1 1 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 OAG36442.1 - 0.092 13.0 0.5 1.7 8.9 0.5 2.7 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Pex24p PF06398.11 OAG36442.1 - 1.8 7.5 5.8 0.55 9.2 1.9 2.0 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin XLF PF09302.11 OAG36443.1 - 1.2e-39 136.3 0.1 2e-39 135.6 0.1 1.3 1 0 0 1 1 1 1 XLF-Cernunnos, XRcc4-like factor, NHEJ component Fungal_trans PF04082.18 OAG36445.1 - 1.4e-13 50.5 0.4 2.2e-13 49.9 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cactin_mid PF10312.9 OAG36446.1 - 2.9e-67 226.2 5.6 2.9e-67 226.2 5.6 1.5 1 1 0 1 1 1 1 Conserved mid region of cactin CactinC_cactus PF09732.9 OAG36446.1 - 2.6e-56 188.9 3.0 4.6e-56 188.1 3.0 1.4 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein FlgN PF05130.12 OAG36446.1 - 0.02 15.4 2.7 0.02 15.4 2.7 2.1 2 0 0 2 2 2 0 FlgN protein FdhE PF04216.12 OAG36446.1 - 0.13 12.1 1.0 0.24 11.2 1.0 1.3 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation DUF2839 PF10999.8 OAG36447.1 - 0.031 14.6 0.2 0.031 14.6 0.2 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF2839) DUF2207 PF09972.9 OAG36447.1 - 0.085 11.6 4.1 0.71 8.6 1.2 2.7 2 1 1 3 3 3 0 Predicted membrane protein (DUF2207) Forkhead PF00250.18 OAG36448.1 - 4.7e-17 62.0 1.2 1.6e-16 60.3 0.2 2.4 2 1 0 2 2 2 1 Forkhead domain Ribosomal_L34e PF01199.18 OAG36449.1 - 2.4e-42 143.2 1.7 3.7e-42 142.5 1.7 1.3 1 0 0 1 1 1 1 Ribosomal protein L34e Vps36-NZF-N PF16988.5 OAG36449.1 - 0.026 13.9 0.4 0.049 13.0 0.0 1.8 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain FhuF_C PF11575.8 OAG36449.1 - 0.36 10.8 4.4 1.7 8.7 0.3 2.6 2 0 0 2 2 2 0 FhuF 2Fe-2S C-terminal domain PROCN PF08083.11 OAG36450.1 - 2.8e-235 780.5 8.0 2.8e-235 780.5 8.0 2.2 2 0 0 2 2 2 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 OAG36450.1 - 4.5e-127 422.4 2.2 8.5e-127 421.5 2.2 1.5 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 OAG36450.1 - 6.3e-85 283.0 1.5 1.2e-57 194.3 0.2 2.9 2 0 0 2 2 2 2 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 OAG36450.1 - 6.2e-82 273.0 2.0 1.6e-81 271.6 2.0 1.8 1 0 0 1 1 1 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 OAG36450.1 - 1.1e-70 236.0 0.1 2.3e-70 234.9 0.1 1.6 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.9 OAG36450.1 - 1.5e-47 159.8 2.6 1.6e-47 159.8 0.3 2.3 2 0 0 2 2 2 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.11 OAG36450.1 - 6.4e-47 158.5 0.0 2.2e-46 156.8 0.0 2.0 1 0 0 1 1 1 1 PROCT (NUC072) domain Hom_end_hint PF05203.16 OAG36450.1 - 9.4e-08 32.3 0.0 9.4e-08 32.3 0.0 1.9 2 0 0 2 2 2 1 Hom_end-associated Hint DUF3425 PF11905.8 OAG36451.1 - 1.9e-12 47.2 0.7 5e-12 45.9 0.7 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) ABC_tran_Xtn PF12848.7 OAG36451.1 - 1.2 9.3 6.6 1.8 8.7 4.9 2.0 2 0 0 2 2 2 0 ABC transporter DLH PF01738.18 OAG36452.1 - 2.6e-21 76.2 0.0 3.3e-21 75.9 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Romo1 PF10247.9 OAG36452.1 - 0.085 13.2 0.0 0.17 12.3 0.0 1.4 1 0 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 Abhydrolase_1 PF00561.20 OAG36452.1 - 0.16 11.6 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold BaxI_1 PF12811.7 OAG36454.1 - 0.0014 18.3 0.1 0.0015 18.1 0.1 1.2 1 0 0 1 1 1 1 Bax inhibitor 1 like HdeA PF06411.11 OAG36454.1 - 0.08 13.1 0.0 0.21 11.8 0.0 1.7 1 0 0 1 1 1 0 HdeA/HdeB family T6PP_N PF18572.1 OAG36454.1 - 0.14 12.0 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain Peptidase_U4 PF03419.13 OAG36454.1 - 2.7 7.2 6.7 4.1 6.6 6.7 1.2 1 0 0 1 1 1 0 Sporulation factor SpoIIGA Sec62 PF03839.16 OAG36455.1 - 0.053 13.0 0.1 0.096 12.2 0.0 1.4 1 1 0 1 1 1 0 Translocation protein Sec62 Serendipity_A PF05482.12 OAG36455.1 - 0.12 11.0 0.1 0.17 10.5 0.1 1.1 1 0 0 1 1 1 0 Serendipity locus alpha protein (SRY-A) Pro_dh PF01619.18 OAG36457.1 - 1.3e-68 231.8 0.9 1.5e-68 231.5 0.9 1.0 1 0 0 1 1 1 1 Proline dehydrogenase DUF4434 PF14488.6 OAG36457.1 - 0.086 12.8 0.1 0.34 10.9 0.1 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4434) Kinesin PF00225.23 OAG36458.1 - 8.8e-117 389.7 0.0 8.8e-117 389.7 0.0 1.7 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 OAG36458.1 - 1.4e-27 96.4 1.5 1.5e-26 93.1 0.0 2.4 2 0 0 2 2 2 1 Microtubule binding DUF932 PF06067.11 OAG36458.1 - 0.066 13.0 4.2 0.14 11.9 4.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF932) Lipoprotein_6 PF01441.19 OAG36458.1 - 0.077 13.0 3.8 0.28 11.2 3.8 1.9 1 0 0 1 1 1 0 Lipoprotein ArgoL2 PF16488.5 OAG36458.1 - 0.15 12.4 0.5 0.57 10.6 0.5 2.1 1 0 0 1 1 1 0 Argonaute linker 2 domain G0-G1_switch_2 PF15103.6 OAG36458.1 - 2.6 8.5 0.0 2.6 8.5 0.0 3.3 4 0 0 4 4 4 0 G0/G1 switch protein 2 FAD_binding_4 PF01565.23 OAG36459.1 - 3.7e-30 104.5 0.2 6.5e-30 103.7 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 OAG36459.1 - 5.7e-12 45.5 0.8 1.9e-11 43.8 0.5 2.1 2 0 0 2 2 2 1 Berberine and berberine like CdiA_C_tRNase PF18664.1 OAG36459.1 - 0.15 12.3 0.1 0.78 9.9 0.1 2.3 1 1 1 2 2 2 0 CdiA C-terminal tRNase domain PMSR PF01625.21 OAG36460.1 - 1.8e-57 193.8 0.0 4.3e-57 192.6 0.1 1.6 2 0 0 2 2 2 1 Peptide methionine sulfoxide reductase Ank_2 PF12796.7 OAG36460.1 - 1.8e-07 31.7 0.1 0.00063 20.3 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OAG36460.1 - 2.8e-05 24.3 0.3 0.046 14.1 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 OAG36460.1 - 0.00051 20.4 2.8 2.9 8.5 0.1 3.6 2 1 1 3 3 3 2 Ankyrin repeat vWA-TerF-like PF10138.9 OAG36460.1 - 0.00059 20.0 0.0 0.0013 18.9 0.0 1.5 1 0 0 1 1 1 1 vWA found in TerF C terminus T2SSF PF00482.23 OAG36460.1 - 0.019 14.9 0.0 0.055 13.4 0.0 1.8 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F VWA PF00092.28 OAG36460.1 - 0.034 14.4 0.0 0.074 13.3 0.0 1.6 1 0 0 1 1 1 0 von Willebrand factor type A domain VWA_2 PF13519.6 OAG36460.1 - 0.06 14.0 0.0 0.34 11.6 0.0 2.2 2 0 0 2 2 2 0 von Willebrand factor type A domain Ig_2 PF13895.6 OAG36460.1 - 0.19 12.1 0.2 0.8 10.1 0.1 2.0 2 0 0 2 2 2 0 Immunoglobulin domain DUF3886 PF13025.6 OAG36461.1 - 0.048 13.9 2.1 0.048 13.9 2.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3886) CDC45 PF02724.14 OAG36461.1 - 1.8 6.7 5.3 2 6.6 5.3 1.0 1 0 0 1 1 1 0 CDC45-like protein adh_short PF00106.25 OAG36462.1 - 7.6e-30 103.8 0.0 1.6e-29 102.8 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG36462.1 - 4.1e-20 72.4 0.0 6.2e-20 71.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG36462.1 - 2e-05 24.6 0.2 0.0011 18.9 0.2 2.7 1 1 0 1 1 1 1 KR domain Membr_traf_MHD PF10540.9 OAG36463.1 - 1.5e-21 77.1 1.2 6.5e-11 42.6 0.3 3.0 1 1 1 2 2 2 2 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.30 OAG36463.1 - 3.1e-14 53.1 0.0 5.5e-13 49.1 0.0 2.7 2 0 0 2 2 2 1 C2 domain DUF810 PF05664.11 OAG36463.1 - 0.00019 20.1 0.4 0.00019 20.1 0.4 2.9 4 0 0 4 4 4 2 Plant family of unknown function (DUF810) FMO-like PF00743.19 OAG36464.1 - 4e-12 45.3 0.0 1.2e-11 43.8 0.0 1.7 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OAG36464.1 - 4.7e-12 45.8 0.1 3.4e-11 43.0 0.0 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAG36464.1 - 1.3e-08 34.4 0.0 1e-05 24.9 0.0 2.3 2 0 0 2 2 2 2 Thi4 family NAD_binding_8 PF13450.6 OAG36464.1 - 1.6e-08 34.7 0.0 3.3e-06 27.2 0.0 2.8 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAG36464.1 - 9.6e-07 28.3 0.1 4.8e-05 22.7 0.0 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG36464.1 - 4.2e-05 22.9 0.0 0.00091 18.5 0.0 2.5 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 OAG36464.1 - 0.00024 20.8 1.0 0.018 14.7 0.1 3.3 3 1 1 4 4 4 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 OAG36464.1 - 0.00039 20.9 0.0 0.051 14.1 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAG36464.1 - 0.012 14.8 0.2 0.081 12.0 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.12 OAG36464.1 - 0.012 14.7 0.1 2 7.4 0.0 2.5 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_7 PF13241.6 OAG36464.1 - 0.019 15.4 0.0 0.05 14.0 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding Shikimate_DH PF01488.20 OAG36464.1 - 0.055 13.5 0.0 0.49 10.5 0.0 2.3 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.6 OAG36464.1 - 0.067 13.2 0.2 7.9 6.5 0.0 3.0 3 0 0 3 3 3 0 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 OAG36464.1 - 0.16 11.3 0.2 6.7 5.9 0.0 2.4 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain DUF2198 PF09964.9 OAG36464.1 - 0.27 11.4 2.1 11 6.1 0.0 3.2 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2198) HI0933_like PF03486.14 OAG36464.1 - 0.5 9.0 1.5 4.9 5.7 0.1 2.3 3 0 0 3 3 3 0 HI0933-like protein p450 PF00067.22 OAG36465.1 - 1.2e-63 215.4 0.0 1.6e-63 215.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ribosomal_S21e PF01249.18 OAG36466.1 - 1.7e-36 124.2 0.1 2.9e-34 117.0 0.0 2.2 2 0 0 2 2 2 2 Ribosomal protein S21e tRNA-synt_2d PF01409.20 OAG36467.1 - 1.5e-87 293.2 0.0 2e-87 292.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 OAG36467.1 - 8.2e-14 51.6 0.3 8.2e-14 51.6 0.3 2.0 2 0 0 2 2 2 1 PheRS DNA binding domain 3 PheRS_DBD2 PF18554.1 OAG36467.1 - 9.4e-07 28.7 0.6 3.7e-06 26.8 0.6 2.1 1 0 0 1 1 1 1 PheRS DNA binding domain 2 tRNA_synthFbeta PF17759.1 OAG36467.1 - 3.9e-06 26.5 0.0 0.0044 16.5 0.0 2.7 3 0 0 3 3 3 2 Phenylalanyl tRNA synthetase beta chain CLM domain tRNA-synt_2 PF00152.20 OAG36467.1 - 4.3e-05 22.8 0.0 0.0029 16.8 0.0 2.9 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) TFIID_NTD2 PF04494.15 OAG36467.1 - 0.08 13.2 0.1 0.3 11.3 0.1 1.9 2 0 0 2 2 2 0 WD40 associated region in TFIID subunit, NTD2 domain MFS_1 PF07690.16 OAG36468.1 - 1.4e-52 178.8 39.3 8e-48 163.2 17.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Histidinol_dh PF00815.20 OAG36469.1 - 3.2e-159 530.3 2.2 4.6e-159 529.8 2.2 1.2 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.18 OAG36469.1 - 2e-23 82.0 0.2 4.1e-23 81.0 0.2 1.5 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.17 OAG36469.1 - 3e-15 56.4 2.5 4e-15 56.0 0.3 2.4 2 0 0 2 2 2 1 Phosphoribosyl-ATP pyrophosphohydrolase Fungal_trans PF04082.18 OAG36469.1 - 0.011 14.7 0.0 0.02 13.9 0.0 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG36469.1 - 0.047 13.8 4.2 0.087 13.0 4.2 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAG36470.1 - 1.3e-07 30.9 0.0 2.4e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG36470.1 - 0.003 17.6 9.9 0.0068 16.5 9.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain bZIP_Maf PF03131.17 OAG36471.1 - 0.001 19.6 7.1 0.0015 19.0 7.1 1.2 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_1 PF00170.21 OAG36471.1 - 0.0011 19.1 6.3 0.002 18.2 6.3 1.5 1 0 0 1 1 1 1 bZIP transcription factor DUF2353 PF09789.9 OAG36471.1 - 0.0019 17.6 0.5 0.0019 17.6 0.5 1.8 1 1 1 2 2 2 1 Uncharacterized coiled-coil protein (DUF2353) MscS_porin PF12795.7 OAG36471.1 - 0.0073 15.9 1.7 0.0091 15.6 1.7 1.2 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain Fungal_trans_2 PF11951.8 OAG36472.1 - 2e-17 63.1 0.4 2.2e-16 59.6 0.4 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain DNA_methylase PF00145.17 OAG36473.1 - 6.1e-09 35.7 0.0 9.1e-08 31.8 0.0 2.7 2 1 0 2 2 2 1 C-5 cytosine-specific DNA methylase Fungal_trans PF04082.18 OAG36474.1 - 3.7e-27 95.0 2.5 7e-27 94.1 1.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Aldedh PF00171.22 OAG36475.1 - 1e-148 495.7 0.0 1.1e-148 495.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 OAG36475.1 - 0.00024 20.6 0.0 0.45 9.9 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) ADH_N PF08240.12 OAG36476.1 - 8.2e-30 102.9 0.4 1.5e-29 102.1 0.4 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG36476.1 - 4.3e-16 59.1 1.3 6.8e-16 58.4 1.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAG36476.1 - 1.1e-09 39.4 0.0 2e-09 38.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Sacchrp_dh_NADP PF03435.18 OAG36476.1 - 0.022 15.0 0.5 0.053 13.8 0.3 1.7 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_8 PF13450.6 OAG36478.1 - 2.1e-06 27.9 0.0 2.5e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.19 OAG36478.1 - 0.0012 17.4 0.5 0.0022 16.5 0.5 1.5 1 1 1 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 OAG36478.1 - 0.0016 17.8 0.0 0.0016 17.8 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAG36478.1 - 0.0091 15.6 0.0 0.0091 15.6 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OAG36478.1 - 0.011 14.9 0.0 0.011 14.9 0.0 1.1 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.6 OAG36478.1 - 0.037 14.0 0.0 0.042 13.8 0.0 1.1 1 0 0 1 1 1 0 FAD-NAD(P)-binding HMGL-like PF00682.19 OAG36479.1 - 1.1e-46 159.6 0.0 2.1e-46 158.7 0.0 1.5 1 0 0 1 1 1 1 HMGL-like ECH_1 PF00378.20 OAG36479.1 - 7.1e-39 133.6 0.0 1.4e-38 132.6 0.0 1.4 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAG36479.1 - 3.4e-27 95.8 0.0 7.2e-27 94.8 0.0 1.5 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase CoA_transf_3 PF02515.17 OAG36480.1 - 4.2e-126 421.0 0.0 4.8e-126 420.8 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III ADH_zinc_N PF00107.26 OAG36481.1 - 7.4e-10 38.9 0.0 1.4e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG36481.1 - 4.9e-06 26.4 0.1 6.4e-05 22.8 0.0 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Kelch_5 PF13854.6 OAG36481.1 - 0.14 12.2 0.1 0.37 10.8 0.1 1.7 1 0 0 1 1 1 0 Kelch motif Acyl-CoA_dh_1 PF00441.24 OAG36482.1 - 3.1e-33 115.1 4.6 5.2e-33 114.4 4.6 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 OAG36482.1 - 1.1e-26 93.7 0.0 2.5e-26 92.5 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 OAG36482.1 - 2.3e-19 69.4 0.0 3.9e-19 68.7 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 OAG36482.1 - 2.8e-14 53.5 2.2 2.8e-14 53.5 2.2 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Glucosaminidase PF01832.20 OAG36482.1 - 0.064 13.8 0.1 0.17 12.4 0.0 1.7 2 0 0 2 2 2 0 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase Mito_carr PF00153.27 OAG36483.1 - 4.2e-52 174.1 0.7 4.7e-16 58.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Pyr_redox_2 PF07992.14 OAG36484.1 - 1.8e-21 76.7 0.0 3.8e-18 65.7 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 OAG36484.1 - 1.9e-15 56.3 0.4 7.3e-13 47.8 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OAG36484.1 - 1.4e-14 54.1 0.0 1.1e-12 47.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG36484.1 - 5.4e-12 45.5 0.1 1.3e-10 40.9 0.0 2.3 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 OAG36484.1 - 2.5e-10 40.4 0.0 1.9e-07 31.2 0.0 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAG36484.1 - 2e-06 27.6 0.5 0.19 11.2 0.1 3.6 1 1 2 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 OAG36484.1 - 2.6e-06 27.5 0.1 2.4 8.1 0.0 4.2 4 0 0 4 4 4 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 OAG36484.1 - 0.00015 22.3 0.1 0.9 10.1 0.1 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OAG36484.1 - 0.00051 19.2 0.1 1.1 8.3 0.0 3.1 3 0 0 3 3 3 1 Glucose inhibited division protein A Thi4 PF01946.17 OAG36484.1 - 0.0042 16.4 0.2 1.9 7.7 0.0 2.6 3 0 0 3 3 3 2 Thi4 family HI0933_like PF03486.14 OAG36484.1 - 0.008 14.9 0.4 5.1 5.7 0.0 3.5 3 0 0 3 3 3 1 HI0933-like protein Lycopene_cycl PF05834.12 OAG36484.1 - 0.01 14.9 0.0 0.22 10.6 0.0 2.7 2 1 0 2 2 2 0 Lycopene cyclase protein FAD_binding_2 PF00890.24 OAG36484.1 - 0.028 13.5 0.1 0.17 10.9 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain Amino_oxidase PF01593.24 OAG36484.1 - 0.046 13.0 0.3 7.4 5.7 0.0 3.5 2 1 1 4 4 4 0 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.21 OAG36484.1 - 0.074 12.3 0.3 2.2 7.5 0.0 2.5 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain DUF5339 PF17274.2 OAG36484.1 - 0.12 13.3 0.8 41 5.1 0.0 3.0 3 0 0 3 3 3 0 Family of unknown function (DUF5339) MFS_1 PF07690.16 OAG36485.1 - 8.8e-41 140.0 28.9 2e-40 138.8 29.4 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 OAG36485.1 - 0.004 16.1 0.2 0.004 16.1 0.2 2.8 2 1 1 3 3 3 1 MFS_1 like family Phage_holin_2_4 PF16082.5 OAG36485.1 - 0.045 13.5 0.2 0.29 10.9 0.0 2.5 3 0 0 3 3 3 0 Bacteriophage holin family, superfamily II-like Fungal_trans PF04082.18 OAG36486.1 - 3.5e-29 101.7 0.0 6.1e-29 100.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG36486.1 - 1.9e-08 34.2 12.2 1.9e-08 34.2 12.2 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AtuA PF07287.11 OAG36487.1 - 4.9e-127 423.5 0.2 6.3e-127 423.1 0.2 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA adh_short_C2 PF13561.6 OAG36488.1 - 5.9e-41 140.6 0.0 9.6e-41 139.9 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG36488.1 - 1.5e-28 99.6 0.0 1.8e-28 99.4 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG36489.1 - 8.5e-55 185.9 0.2 1.5e-54 185.0 0.2 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG36489.1 - 1.6e-40 138.7 1.4 3.9e-40 137.4 1.4 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG36489.1 - 1.6e-07 31.4 0.2 2.2e-07 31.0 0.2 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OAG36489.1 - 0.0005 19.3 0.1 0.00081 18.6 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Methyltransf_25 PF13649.6 OAG36489.1 - 0.0086 16.8 0.1 0.018 15.7 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.21 OAG36489.1 - 0.074 12.5 0.4 0.39 10.1 0.2 2.0 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family Toprim_2 PF13155.6 OAG36489.1 - 0.12 12.8 0.1 0.67 10.4 0.0 2.2 3 0 0 3 3 3 0 Toprim-like AMP-binding PF00501.28 OAG36490.1 - 5.1e-37 127.5 0.0 7.1e-37 127.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG36490.1 - 9.2e-06 26.5 0.0 2e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 OAG36490.1 - 4.5e-05 23.3 1.2 4.5e-05 23.3 1.2 1.8 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus adh_short PF00106.25 OAG36491.1 - 2.8e-36 124.8 0.1 3.4e-36 124.5 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG36491.1 - 3e-26 92.4 0.2 3.7e-26 92.1 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG36491.1 - 0.00019 21.4 0.1 0.00068 19.6 0.1 1.8 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 OAG36491.1 - 0.012 14.6 0.1 0.022 13.7 0.1 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 OAG36492.1 - 3.5e-29 101.7 0.0 6.1e-29 100.9 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG36492.1 - 1.1e-21 77.4 0.1 8.3e-21 74.6 0.1 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG36492.1 - 1.9e-06 27.9 0.3 7.1e-06 26.1 0.3 1.9 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG36492.1 - 0.00013 21.6 0.0 0.00015 21.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OAG36492.1 - 0.00021 20.4 0.0 0.00025 20.1 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family 3HCDH_N PF02737.18 OAG36492.1 - 0.0089 15.9 0.1 0.012 15.5 0.1 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ldh_1_N PF00056.23 OAG36492.1 - 0.013 15.6 0.2 0.024 14.7 0.2 1.4 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Urocanase PF01175.18 OAG36492.1 - 0.017 14.8 0.1 0.023 14.3 0.1 1.1 1 0 0 1 1 1 0 Urocanase Rossmann-like domain Sarcoglycan_2 PF05510.13 OAG36492.1 - 0.037 12.8 0.0 0.047 12.4 0.0 1.1 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon GDP_Man_Dehyd PF16363.5 OAG36492.1 - 0.043 13.2 0.0 0.059 12.7 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase THF_DHG_CYH_C PF02882.19 OAG36492.1 - 0.11 11.8 0.0 3.5 6.9 0.0 2.1 1 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Polysacc_synt_2 PF02719.15 OAG36492.1 - 0.17 11.0 0.0 0.21 10.7 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein ThiF PF00899.21 OAG36492.1 - 0.22 10.9 1.0 0.48 9.7 0.5 1.7 1 1 1 2 2 2 0 ThiF family Sugar_tr PF00083.24 OAG36493.1 - 3.3e-71 240.5 31.9 3.8e-71 240.3 31.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG36493.1 - 5.5e-20 71.6 41.2 5.8e-19 68.2 28.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Bac_luciferase PF00296.20 OAG36494.1 - 9.7e-59 199.3 0.5 1.4e-58 198.8 0.5 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase ECH_1 PF00378.20 OAG36495.1 - 4.3e-56 190.0 0.1 6.1e-56 189.5 0.1 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAG36495.1 - 4.2e-20 72.5 0.9 1.8e-18 67.1 0.3 2.3 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 OAG36495.1 - 0.0013 18.7 0.4 0.43 10.5 0.1 2.3 1 1 1 2 2 2 2 Peptidase family S49 DoxD PF04173.13 OAG36495.1 - 0.083 12.8 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 TQO small subunit DoxD Glycolytic PF00274.19 OAG36496.1 - 8.3e-68 228.7 1.4 1.6e-33 115.9 0.2 2.9 1 1 1 2 2 2 2 Fructose-bisphosphate aldolase class-I Cupin_2 PF07883.11 OAG36497.1 - 5e-10 39.0 0.1 1.6e-09 37.3 0.1 1.9 2 0 0 2 2 2 1 Cupin domain Cupin_1 PF00190.22 OAG36497.1 - 0.006 16.2 0.0 0.0082 15.8 0.0 1.3 1 0 0 1 1 1 1 Cupin ARD PF03079.14 OAG36497.1 - 0.17 12.1 0.0 0.25 11.5 0.0 1.3 1 0 0 1 1 1 0 ARD/ARD' family ABC_tran PF00005.27 OAG36498.1 - 8.7e-47 159.1 0.0 1.9e-28 99.7 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 OAG36498.1 - 2.8e-33 115.8 49.6 6e-23 81.9 19.8 4.1 4 0 0 4 4 4 3 ABC transporter transmembrane region SMC_N PF02463.19 OAG36498.1 - 9.5e-14 51.4 1.6 2.7e-05 23.7 0.1 4.2 2 2 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 OAG36498.1 - 1.8e-09 38.4 0.2 0.0022 18.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.6 OAG36498.1 - 6.6e-08 32.7 0.7 0.12 12.2 0.0 4.3 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 OAG36498.1 - 3.8e-07 30.5 0.1 0.019 15.2 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.6 OAG36498.1 - 2.2e-06 27.3 0.9 0.00047 19.8 0.2 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain T2SSE PF00437.20 OAG36498.1 - 2.5e-05 23.5 0.1 0.019 14.1 0.1 2.5 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_16 PF13191.6 OAG36498.1 - 8.8e-05 22.9 0.8 0.37 11.2 0.3 3.3 2 1 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 OAG36498.1 - 0.00021 21.3 0.0 0.81 9.6 0.0 3.0 3 0 0 3 3 2 2 RsgA GTPase AAA_25 PF13481.6 OAG36498.1 - 0.0011 18.6 0.1 0.043 13.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 OAG36498.1 - 0.0036 17.4 0.4 0.0074 16.4 0.4 1.5 1 0 0 1 1 1 1 Helicase HerA, central domain cobW PF02492.19 OAG36498.1 - 0.0042 16.7 0.8 2 8.0 0.0 2.6 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 OAG36498.1 - 0.006 16.7 0.0 1.5 8.9 0.0 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 OAG36498.1 - 0.061 13.4 0.0 2.5 8.2 0.0 2.5 2 0 0 2 2 2 0 Dynamin family ATPase_2 PF01637.18 OAG36498.1 - 0.066 13.1 0.0 4.2 7.2 0.0 2.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_33 PF13671.6 OAG36498.1 - 0.075 13.2 0.1 11 6.2 0.1 2.7 2 1 0 2 2 2 0 AAA domain NACHT PF05729.12 OAG36498.1 - 0.082 12.8 0.5 2.5 8.0 0.0 3.2 3 0 0 3 3 3 0 NACHT domain NTPase_1 PF03266.15 OAG36498.1 - 0.2 11.5 0.1 0.79 9.6 0.0 2.1 2 0 0 2 2 2 0 NTPase Zeta_toxin PF06414.12 OAG36498.1 - 0.24 10.6 0.4 7.1 5.8 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin TsaE PF02367.17 OAG36498.1 - 0.6 10.1 1.7 15 5.6 0.1 2.9 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_ATPase PF09818.9 OAG36498.1 - 0.65 8.7 1.8 6.1 5.5 0.1 2.7 3 0 0 3 3 3 0 Predicted ATPase of the ABC class AAA_30 PF13604.6 OAG36498.1 - 0.9 9.2 2.6 3.5 7.3 1.0 2.5 2 1 0 2 2 2 0 AAA domain Aa_trans PF01490.18 OAG36499.1 - 6.2e-82 275.5 27.2 8.3e-82 275.1 27.2 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein PGA_cap PF09587.10 OAG36501.1 - 2.7e-63 213.8 0.0 3.3e-63 213.5 0.0 1.1 1 0 0 1 1 1 1 Bacterial capsule synthesis protein PGA_cap OCD_Mu_crystall PF02423.15 OAG36502.1 - 1.4e-11 43.9 0.0 2.5e-11 43.1 0.0 1.5 1 1 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.20 OAG36502.1 - 6.1e-06 26.4 0.0 4.1e-05 23.7 0.0 2.3 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase GFO_IDH_MocA PF01408.22 OAG36502.1 - 0.021 15.6 0.0 0.038 14.8 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_7 PF13241.6 OAG36502.1 - 0.036 14.5 0.0 0.068 13.6 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding TruB_C PF09142.11 OAG36502.1 - 0.054 13.3 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 tRNA Pseudouridine synthase II, C terminal DUF3739 PF12545.8 OAG36502.1 - 0.12 12.8 0.0 0.27 11.7 0.0 1.5 1 0 0 1 1 1 0 Filamentous haemagglutinin family outer membrane protein PhyH PF05721.13 OAG36503.1 - 1.5e-12 48.3 0.0 2.2e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Sugar_tr PF00083.24 OAG36504.1 - 3.4e-102 342.6 22.9 4.3e-102 342.3 22.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG36504.1 - 2.5e-22 79.3 25.9 2.5e-22 79.3 25.9 2.5 1 1 2 3 3 3 2 Major Facilitator Superfamily Fungal_trans_2 PF11951.8 OAG36504.1 - 3.4e-08 32.7 0.0 6.2e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG36504.1 - 7.3e-08 32.4 12.7 1.2e-07 31.7 12.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain OATP PF03137.20 OAG36504.1 - 1.2 7.3 7.3 0.082 11.2 0.9 2.1 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family PhyH PF05721.13 OAG36505.1 - 5.2e-14 53.0 0.0 9.4e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Fungal_trans_2 PF11951.8 OAG36505.1 - 0.00017 20.5 0.3 0.00026 19.9 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DEAD_2 PF06733.15 OAG36506.1 - 1e-51 175.0 0.0 1.9e-51 174.2 0.0 1.4 1 0 0 1 1 1 1 DEAD_2 HBB PF06777.11 OAG36506.1 - 1.7e-47 161.6 2.9 4e-43 147.3 0.8 2.4 2 0 0 2 2 2 2 Helical and beta-bridge domain Helicase_C_2 PF13307.6 OAG36506.1 - 5.1e-43 147.2 0.0 1.5e-42 145.7 0.0 1.8 2 0 0 2 2 2 1 Helicase C-terminal domain Remorin_C PF03763.13 OAG36506.1 - 0.39 10.6 3.6 1 9.3 3.6 1.6 1 0 0 1 1 1 0 Remorin, C-terminal region zf-RING_2 PF13639.6 OAG36507.1 - 6.7e-08 32.7 7.0 2.3e-07 31.0 7.0 2.0 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 OAG36507.1 - 9.3e-05 22.6 6.1 0.00027 21.1 6.1 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 OAG36507.1 - 0.00014 21.8 2.0 0.00041 20.4 2.0 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 OAG36507.1 - 0.00021 21.4 4.3 0.00054 20.1 4.3 1.7 1 0 0 1 1 1 1 FANCL C-terminal domain zf-C3HC4_2 PF13923.6 OAG36507.1 - 0.0049 16.7 5.8 0.013 15.3 5.8 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAG36507.1 - 0.0085 15.9 6.7 0.02 14.8 6.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 OAG36507.1 - 0.04 13.5 3.9 0.1 12.2 3.9 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type RWD PF05773.22 OAG36507.1 - 0.12 12.7 0.3 0.73 10.1 0.0 2.4 2 0 0 2 2 2 0 RWD domain Thioredoxin_16 PF18569.1 OAG36507.1 - 0.69 10.1 6.0 5.4 7.2 0.1 4.1 2 1 1 3 3 3 0 Thioredoxin-like domain zf-C3HC4_3 PF13920.6 OAG36507.1 - 1 9.3 3.9 2.4 8.1 3.9 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OAG36507.1 - 3.9 7.4 6.0 11 6.0 6.0 1.9 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 LCM PF04072.14 OAG36508.1 - 1.6e-21 77.1 0.0 3.9e-21 75.9 0.0 1.6 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase SUN PF03856.13 OAG36509.1 - 6.7e-79 264.8 13.8 1.1e-78 264.0 13.8 1.4 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) Sugarporin_N PF11471.8 OAG36509.1 - 0.017 15.1 0.5 0.058 13.4 0.5 2.0 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension YL1 PF05764.13 OAG36510.1 - 0.88 9.6 11.7 1.8 8.6 11.7 1.4 1 0 0 1 1 1 0 YL1 nuclear protein CDC45 PF02724.14 OAG36510.1 - 2.8 6.1 9.0 4 5.6 9.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Ist1 PF03398.14 OAG36511.1 - 5.2e-44 150.1 0.3 6.7e-44 149.7 0.3 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Clat_adaptor_s PF01217.20 OAG36512.1 - 7e-51 171.9 4.1 5.1e-50 169.1 4.1 1.8 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Mito_carr PF00153.27 OAG36513.1 - 1.8e-59 197.6 4.3 7.8e-20 70.6 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein 7tm_1 PF00001.21 OAG36514.1 - 0.00049 19.5 0.0 0.0013 18.1 0.0 1.7 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) HSNSD PF12062.8 OAG36514.1 - 0.029 13.1 0.0 0.042 12.6 0.0 1.1 1 0 0 1 1 1 0 heparan sulfate-N-deacetylase UQ_con PF00179.26 OAG36515.1 - 1.3e-42 144.7 0.0 1.5e-42 144.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme INCENP_ARK-bind PF03941.15 OAG36516.1 - 6.6e-18 64.4 0.9 6.6e-18 64.4 0.9 2.9 3 0 0 3 3 3 1 Inner centromere protein, ARK binding region Acyl-CoA_dh_1 PF00441.24 OAG36517.1 - 1.7e-31 109.5 3.1 2.7e-31 108.8 3.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 OAG36517.1 - 1.5e-20 73.2 0.0 2.6e-20 72.4 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 OAG36517.1 - 5.2e-20 72.2 0.1 1.2e-19 71.0 0.1 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 OAG36517.1 - 2.7e-15 56.8 2.9 2.7e-15 56.8 2.9 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain TPR_1 PF00515.28 OAG36518.1 - 0.0021 17.8 0.7 8.1 6.5 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 OAG36518.1 - 0.019 15.1 10.9 0.33 11.2 0.0 4.2 4 1 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 OAG36518.1 - 0.03 14.5 0.6 0.086 13.1 0.6 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 Drf_DAD PF06345.11 OAG36518.1 - 0.1 12.7 1.2 1.4 9.2 0.1 3.1 2 0 0 2 2 2 0 DRF Autoregulatory Domain Pox_T4_N PF04491.12 OAG36518.1 - 0.19 11.6 0.0 0.45 10.4 0.0 1.5 1 0 0 1 1 1 0 Poxvirus T4 protein, N terminus TPR_14 PF13428.6 OAG36518.1 - 0.55 11.2 3.5 1.7 9.6 0.1 3.4 3 1 1 4 4 4 0 Tetratricopeptide repeat SSXT PF05030.12 OAG36519.1 - 4.9e-06 26.1 4.0 0.026 14.2 0.0 2.8 3 0 0 3 3 3 2 SSXT protein (N-terminal region) PDZ_1 PF12812.7 OAG36520.1 - 3.2e-54 180.9 0.0 1.4e-35 121.2 0.0 2.8 2 0 0 2 2 2 2 PDZ-like domain Trypsin_2 PF13365.6 OAG36520.1 - 7.2e-24 85.4 1.6 1.9e-21 77.5 0.1 2.5 2 0 0 2 2 2 2 Trypsin-like peptidase domain PDZ_6 PF17820.1 OAG36520.1 - 2.5e-15 56.1 0.9 5.3e-08 32.6 0.1 3.7 3 0 0 3 3 3 3 PDZ domain PDZ_2 PF13180.6 OAG36520.1 - 8e-14 51.7 0.2 2e-05 24.8 0.0 3.8 3 0 0 3 3 3 3 PDZ domain PDZ PF00595.24 OAG36520.1 - 2.2e-11 44.0 0.0 8.6e-06 26.0 0.0 3.7 3 0 0 3 3 3 2 PDZ domain Trypsin PF00089.26 OAG36520.1 - 3.6e-06 27.0 0.1 1.6e-05 24.8 0.0 2.1 2 1 0 2 2 2 1 Trypsin Peptidase_S46 PF10459.9 OAG36520.1 - 0.0028 16.4 1.0 0.004 15.9 0.1 1.6 2 0 0 2 2 2 1 Peptidase S46 Tricorn_PDZ PF14685.6 OAG36520.1 - 0.018 15.0 0.1 1.2 9.2 0.1 3.2 3 0 0 3 3 3 0 Tricorn protease PDZ domain 4HPAD_g_N PF18671.1 OAG36520.1 - 0.11 12.2 0.0 0.37 10.5 0.0 1.9 1 0 0 1 1 1 0 4-Hydroxyphenylacetate decarboxylase subunit gamma N-terminal Peptidase_S7 PF00949.21 OAG36520.1 - 0.12 12.2 0.1 0.26 11.1 0.1 1.5 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease adh_short_C2 PF13561.6 OAG36521.1 - 1.1e-35 123.3 3.0 6.3e-21 75.0 1.5 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG36521.1 - 4.8e-29 101.2 4.8 3.5e-23 82.1 1.6 2.2 1 1 1 2 2 2 2 short chain dehydrogenase KR PF08659.10 OAG36521.1 - 4.2e-10 39.8 0.8 7.7e-10 39.0 0.7 1.5 1 1 0 1 1 1 1 KR domain DDE_3 PF13358.6 OAG36522.1 - 1.4e-07 31.4 0.2 2.7e-07 30.4 0.2 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 OAG36522.1 - 4.4e-06 26.9 0.0 3.1e-05 24.1 0.0 2.4 2 0 0 2 2 2 1 Transposase HTH_23 PF13384.6 OAG36522.1 - 0.2 11.5 4.2 0.58 10.0 0.0 3.5 5 0 0 5 5 5 0 Homeodomain-like domain ABC_trans_N PF14510.6 OAG36525.1 - 0.0012 19.4 0.0 0.0025 18.4 0.0 1.5 1 0 0 1 1 1 1 ABC-transporter N-terminal ABC_tran PF00005.27 OAG36525.1 - 0.0015 19.1 0.0 0.0022 18.5 0.0 1.4 1 0 0 1 1 1 1 ABC transporter TraN PF06986.11 OAG36525.1 - 0.089 12.5 0.1 5.2 6.7 0.0 2.1 1 1 1 2 2 2 0 Type-1V conjugative transfer system mating pair stabilisation DUF4209 PF13910.6 OAG36525.1 - 0.19 12.0 0.0 7.5 6.9 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4209) Transport_MerF PF11431.8 OAG36530.1 - 0.14 12.1 0.5 0.25 11.3 0.5 1.4 1 0 0 1 1 1 0 Membrane transport protein MerF TyeA PF09059.10 OAG36531.1 - 0.14 12.3 0.0 0.22 11.7 0.0 1.3 1 0 0 1 1 1 0 TyeA RRXRR PF14239.6 OAG36532.1 - 0.0027 17.6 1.5 0.0038 17.1 1.5 1.2 1 0 0 1 1 1 1 RRXRR protein TPR_4 PF07721.14 OAG36534.1 - 0.12 13.1 0.0 0.12 13.1 0.0 2.8 4 0 0 4 4 4 0 Tetratricopeptide repeat MULE PF10551.9 OAG36536.1 - 1.1e-12 48.2 0.0 2e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.18 OAG36536.1 - 0.0021 17.0 0.0 0.0038 16.1 0.0 1.3 1 0 0 1 1 1 1 Transposase, Mutator family DUF2379 PF09543.10 OAG36537.1 - 0.16 12.2 2.2 1.8 8.8 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2379) Aldedh PF00171.22 OAG36539.1 - 6.8e-36 123.8 0.6 3.6e-35 121.4 0.6 1.8 1 1 0 1 1 1 1 Aldehyde dehydrogenase family MFS_1 PF07690.16 OAG36541.1 - 8.7e-05 21.6 3.7 0.0001 21.4 3.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DDHD PF02862.17 OAG36542.1 - 0.013 15.7 2.2 0.013 15.7 2.2 1.1 1 0 0 1 1 1 0 DDHD domain RNA_pol_Rpc4 PF05132.14 OAG36542.1 - 0.021 15.3 10.4 0.026 14.9 10.4 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF913 PF06025.12 OAG36542.1 - 0.033 13.2 8.5 0.035 13.1 8.5 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SAPS PF04499.15 OAG36542.1 - 0.065 12.0 11.0 0.064 12.0 11.0 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CLN3 PF02487.17 OAG36542.1 - 0.065 12.3 4.6 0.067 12.2 4.6 1.2 1 0 0 1 1 1 0 CLN3 protein DUF2151 PF10221.9 OAG36542.1 - 0.072 11.7 10.5 0.073 11.7 10.5 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator V_ATPase_I PF01496.19 OAG36542.1 - 0.083 10.8 11.4 0.086 10.7 11.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Paf1 PF03985.13 OAG36542.1 - 0.085 11.8 38.8 0.12 11.4 38.8 1.3 1 0 0 1 1 1 0 Paf1 PIP5K PF01504.18 OAG36542.1 - 0.11 11.8 3.6 0.11 11.7 3.6 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase SID-1_RNA_chan PF13965.6 OAG36542.1 - 0.12 10.8 2.6 0.13 10.7 2.6 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 PTPRCAP PF15713.5 OAG36542.1 - 0.12 12.6 35.5 0.19 12.0 35.5 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated SpoIIP PF07454.11 OAG36542.1 - 0.13 11.7 16.9 0.16 11.4 16.9 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF5308 PF17233.2 OAG36542.1 - 0.14 12.4 1.7 0.16 12.2 1.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5308) Gti1_Pac2 PF09729.9 OAG36542.1 - 0.15 12.2 4.5 0.17 12.0 4.5 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family SpoIIIAH PF12685.7 OAG36542.1 - 0.17 11.7 14.6 0.21 11.4 14.6 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein Plasmodium_Vir PF05795.11 OAG36542.1 - 0.18 11.2 10.2 0.19 11.1 10.2 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Serinc PF03348.15 OAG36542.1 - 0.19 10.6 3.8 0.2 10.6 3.8 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) RAB3GAP2_C PF14656.6 OAG36542.1 - 0.2 9.8 7.4 0.28 9.4 7.4 1.4 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus CDC45 PF02724.14 OAG36542.1 - 0.24 9.7 30.6 0.28 9.4 30.6 1.0 1 0 0 1 1 1 0 CDC45-like protein Neur_chan_memb PF02932.16 OAG36542.1 - 0.29 11.2 2.5 0.31 11.1 2.5 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Afi1 PF07792.12 OAG36542.1 - 0.29 11.6 16.9 0.39 11.2 16.9 1.2 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF740 PF05340.12 OAG36542.1 - 0.38 9.4 17.6 0.38 9.5 17.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF740) RR_TM4-6 PF06459.12 OAG36542.1 - 0.44 10.3 27.3 0.52 10.1 27.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Coilin_N PF15862.5 OAG36542.1 - 0.61 9.9 11.3 0.78 9.5 11.3 1.2 1 0 0 1 1 1 0 Coilin N-terminus Mpp10 PF04006.12 OAG36542.1 - 0.7 8.3 40.5 0.82 8.0 40.5 1.1 1 0 0 1 1 1 0 Mpp10 protein Paramyxo_ncap PF00973.19 OAG36542.1 - 0.81 8.5 6.2 0.88 8.4 6.2 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Presenilin PF01080.17 OAG36542.1 - 0.87 8.3 17.5 1.1 8.0 17.5 1.1 1 0 0 1 1 1 0 Presenilin Nop14 PF04147.12 OAG36542.1 - 0.88 7.7 43.6 1 7.5 43.6 1.0 1 0 0 1 1 1 0 Nop14-like family Vinculin PF01044.19 OAG36542.1 - 1.1 7.4 10.9 1.1 7.4 10.9 1.0 1 0 0 1 1 1 0 Vinculin family Drc1-Sld2 PF11719.8 OAG36542.1 - 1.4 8.4 25.0 1.6 8.2 25.0 1.0 1 0 0 1 1 1 0 DNA replication and checkpoint protein MCM_bind PF09739.9 OAG36542.1 - 1.5 7.2 12.2 1.7 7.0 12.2 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor DUF4045 PF13254.6 OAG36542.1 - 1.7 8.2 14.8 2 7.9 14.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Eapp_C PF10238.9 OAG36542.1 - 2 8.5 13.0 3.1 7.9 13.0 1.4 1 0 0 1 1 1 0 E2F-associated phosphoprotein Med4 PF10018.9 OAG36542.1 - 2.2 7.9 20.3 3.5 7.3 20.3 1.4 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 Hid1 PF12722.7 OAG36542.1 - 2.5 6.1 12.5 2.8 6.0 12.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PPL5 PF18168.1 OAG36542.1 - 2.8 7.1 12.6 3.3 6.9 12.6 1.1 1 0 0 1 1 1 0 Prim-pol family 5 NPR3 PF03666.13 OAG36542.1 - 2.9 6.6 16.5 3.4 6.4 16.5 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SLC12 PF03522.15 OAG36542.1 - 3.4 6.6 11.8 4.1 6.3 11.8 1.0 1 0 0 1 1 1 0 Solute carrier family 12 SDA1 PF05285.12 OAG36542.1 - 3.6 6.9 42.9 4.4 6.6 42.9 1.1 1 0 0 1 1 1 0 SDA1 Polyoma_lg_T_C PF06431.11 OAG36542.1 - 3.9 6.3 4.6 4.6 6.0 4.6 1.3 1 0 0 1 1 1 0 Polyomavirus large T antigen C-terminus AAA_11 PF13086.6 OAG36542.1 - 4 7.2 11.7 4.4 7.0 11.7 1.1 1 0 0 1 1 1 0 AAA domain CCSAP PF15748.5 OAG36542.1 - 4.1 7.5 19.8 5 7.2 19.8 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated FAM91_C PF14648.6 OAG36542.1 - 4.6 6.0 5.8 5.4 5.7 5.8 1.1 1 0 0 1 1 1 0 FAM91 C-terminus BT1 PF03092.16 OAG36542.1 - 4.9 5.3 4.0 5.5 5.1 4.0 1.2 1 0 0 1 1 1 0 BT1 family FGF-BP1 PF06473.12 OAG36542.1 - 5.2 6.8 15.6 7.1 6.4 15.6 1.2 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) Sec62 PF03839.16 OAG36542.1 - 5.7 6.4 13.4 7.6 6.0 13.4 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Vfa1 PF08432.10 OAG36542.1 - 6 7.2 22.9 7.4 6.9 22.9 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DNA_pol_phi PF04931.13 OAG36542.1 - 6.4 4.7 52.3 8 4.4 52.3 1.0 1 0 0 1 1 1 0 DNA polymerase phi DUF3391 PF11871.8 OAG36542.1 - 6.6 7.3 18.9 9.9 6.7 18.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) DUF3306 PF11748.8 OAG36542.1 - 7.4 7.5 22.7 10 7.0 22.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) DUF2828 PF11443.8 OAG36542.1 - 9 4.2 13.0 12 3.8 13.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Pneumovirus_M2 PF06436.11 OAG36543.1 - 0.15 11.5 0.0 0.23 10.9 0.0 1.2 1 0 0 1 1 1 0 Pneumovirus matrix protein 2 (M2) Sporozoite_P67 PF05642.11 OAG36544.1 - 0.025 12.7 0.5 0.027 12.6 0.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen FAM176 PF14851.6 OAG36544.1 - 0.092 12.4 0.1 0.18 11.5 0.1 1.4 1 0 0 1 1 1 0 FAM176 family HSP90 PF00183.18 OAG36545.1 - 7.3e-19 68.0 0.1 8e-19 67.9 0.1 1.0 1 0 0 1 1 1 1 Hsp90 protein zf-B_box PF00643.24 OAG36546.1 - 0.0025 17.9 4.0 0.013 15.6 2.6 2.1 2 0 0 2 2 2 1 B-box zinc finger DUF4379 PF14311.6 OAG36546.1 - 8 6.9 8.8 30 5.1 8.9 2.1 1 1 0 1 1 1 0 Probable Zinc-ribbon domain ANTH PF07651.16 OAG36548.1 - 7.1e-70 235.1 0.0 7.1e-70 235.1 0.0 2.9 2 1 0 2 2 2 1 ANTH domain I_LWEQ PF01608.17 OAG36548.1 - 1.4e-53 181.2 10.0 1.4e-53 181.2 10.0 6.4 4 1 0 6 6 6 1 I/LWEQ domain T7SS_ESX_EspC PF10824.8 OAG36548.1 - 0.22 12.0 0.1 0.22 12.0 0.1 5.9 4 2 1 5 5 5 0 Excreted virulence factor EspC, type VII ESX diderm Glyco_hydro_64 PF16483.5 OAG36549.1 - 5.9e-142 473.3 0.6 6.8e-142 473.1 0.6 1.0 1 0 0 1 1 1 1 Beta-1,3-glucanase UBX PF00789.20 OAG36549.1 - 0.16 12.2 0.0 0.31 11.3 0.0 1.4 1 0 0 1 1 1 0 UBX domain MMM1 PF10296.9 OAG36550.1 - 6.6e-07 28.7 0.0 2.5e-06 26.8 0.0 1.7 2 0 0 2 2 2 1 Maintenance of mitochondrial morphology protein 1 CN_hydrolase PF00795.22 OAG36552.1 - 8.8e-33 113.7 0.0 9.8e-29 100.5 0.0 2.2 2 0 0 2 2 2 2 Carbon-nitrogen hydrolase MMS1_N PF10433.9 OAG36553.1 - 9.3e-157 522.6 0.0 1.3e-156 522.1 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 OAG36553.1 - 1e-96 324.1 0.0 6.8e-96 321.4 0.0 2.3 3 0 0 3 3 3 1 CPSF A subunit region ANAPC4_WD40 PF12894.7 OAG36553.1 - 0.013 15.8 0.0 1 9.7 0.0 3.9 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain BBS2_N PF14781.6 OAG36553.1 - 0.15 12.0 0.0 18 5.3 0.0 3.4 3 1 0 3 3 3 0 Ciliary BBSome complex subunit 2, N-terminal ubiquitin PF00240.23 OAG36554.1 - 5.6e-19 67.7 0.0 8.9e-19 67.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 OAG36554.1 - 6e-11 42.0 0.3 6e-11 42.0 0.3 2.2 2 0 0 2 2 2 1 UBA/TS-N domain Rad60-SLD_2 PF13881.6 OAG36554.1 - 1.3e-05 25.2 0.2 2.5e-05 24.4 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 OAG36554.1 - 6.9e-05 23.3 0.1 0.00015 22.3 0.1 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD PF11976.8 OAG36554.1 - 8.8e-05 22.3 0.0 0.00016 21.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like HOIP-UBA PF16678.5 OAG36554.1 - 0.015 15.3 0.0 0.033 14.2 0.0 1.5 1 0 0 1 1 1 0 HOIP UBA domain pair Ubiquitin_5 PF18037.1 OAG36554.1 - 0.036 14.4 0.0 0.061 13.7 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-like domain Parvo_coat_N PF08398.10 OAG36554.1 - 0.11 12.6 0.7 0.64 10.2 0.1 2.5 2 0 0 2 2 2 0 Parvovirus coat protein VP1 EBV-NA3 PF05009.12 OAG36554.1 - 0.12 11.9 0.1 0.24 10.9 0.1 1.4 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) HET PF06985.11 OAG36556.1 - 6.4e-33 114.2 0.0 1.4e-32 113.0 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) TPR_10 PF13374.6 OAG36556.1 - 0.02 14.8 0.0 0.057 13.3 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat Acetyltransf_15 PF17013.5 OAG36556.1 - 0.029 13.8 0.0 0.049 13.1 0.0 1.2 1 0 0 1 1 1 0 Putative acetyl-transferase Peptidase_M50 PF02163.22 OAG36556.1 - 0.17 11.1 0.0 0.26 10.5 0.0 1.1 1 0 0 1 1 1 0 Peptidase family M50 T2SSM_b PF10741.9 OAG36556.1 - 0.19 11.5 0.0 0.36 10.6 0.0 1.3 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M subtype b adh_short_C2 PF13561.6 OAG36557.1 - 7.7e-42 143.4 0.0 2.3e-40 138.6 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG36557.1 - 6.3e-35 120.4 0.0 7.8e-35 120.1 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG36557.1 - 2e-12 47.4 0.0 2.6e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG36557.1 - 0.00041 19.9 0.0 0.0022 17.5 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 OAG36557.1 - 0.0082 15.3 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 OAG36557.1 - 0.045 12.7 0.0 0.067 12.2 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 OAG36557.1 - 0.13 11.3 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein ADH_N PF08240.12 OAG36558.1 - 1.8e-28 98.6 0.5 3.4e-28 97.7 0.5 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG36558.1 - 3.5e-24 85.3 0.0 5e-24 84.8 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 OAG36558.1 - 1.3e-05 24.8 0.1 2.9e-05 23.7 0.1 1.5 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 OAG36558.1 - 4.3e-05 24.6 0.0 8.5e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 OAG36558.1 - 0.0016 18.4 0.0 0.0045 16.9 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated Sacchrp_dh_NADP PF03435.18 OAG36558.1 - 0.0058 16.9 0.1 0.0094 16.2 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 OAG36558.1 - 0.011 16.0 0.0 0.018 15.3 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Shikimate_DH PF01488.20 OAG36558.1 - 0.036 14.1 0.0 0.065 13.3 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 OAG36558.1 - 0.036 14.6 0.0 0.11 13.0 0.0 1.8 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent FAD_binding_3 PF01494.19 OAG36558.1 - 0.041 13.1 0.3 0.06 12.6 0.3 1.1 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 OAG36558.1 - 0.053 12.8 0.2 0.078 12.2 0.2 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAG36558.1 - 0.071 12.7 0.4 0.11 12.1 0.4 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.19 OAG36558.1 - 0.076 12.4 0.0 0.2 11.0 0.0 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain XdhC_C PF13478.6 OAG36558.1 - 0.078 13.5 0.1 0.12 12.9 0.1 1.3 1 0 0 1 1 1 0 XdhC Rossmann domain EthD PF07110.11 OAG36559.1 - 0.0097 17.0 0.0 0.032 15.4 0.0 1.7 1 1 0 1 1 1 1 EthD domain WD40 PF00400.32 OAG36560.1 - 5.1e-09 36.6 9.0 0.15 13.0 0.2 6.5 7 0 0 7 7 7 4 WD domain, G-beta repeat Methyltransf_16 PF10294.9 OAG36561.1 - 1.8e-19 70.1 0.0 2.8e-19 69.5 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 OAG36561.1 - 3.9e-05 23.5 0.0 6e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG36563.1 - 1e-22 80.6 0.0 1.7e-22 79.8 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG36563.1 - 7.5e-22 77.8 0.0 2.6e-21 76.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG36563.1 - 1.3e-20 73.9 0.0 4.6e-20 72.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG36563.1 - 8.7e-14 52.1 0.0 1.6e-13 51.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAG36563.1 - 1.8e-11 44.2 0.0 2.8e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAG36563.1 - 2.1e-10 40.4 0.0 2.9e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 OAG36563.1 - 1.2e-08 34.7 0.0 2.5e-08 33.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_8 PF05148.15 OAG36563.1 - 2e-05 24.6 0.0 0.0002 21.3 0.0 1.9 2 0 0 2 2 2 1 Hypothetical methyltransferase Methyltransf_9 PF08003.11 OAG36563.1 - 0.00042 19.4 0.0 0.00058 18.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_2 PF00891.18 OAG36563.1 - 0.0018 17.6 0.0 0.0021 17.4 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain MetW PF07021.12 OAG36563.1 - 0.0021 17.7 0.0 0.0058 16.2 0.0 1.6 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW PCMT PF01135.19 OAG36563.1 - 0.0025 17.6 0.0 0.0037 17.0 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.17 OAG36563.1 - 0.0027 17.2 0.0 0.029 13.8 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase FtsJ PF01728.19 OAG36563.1 - 0.012 15.8 0.0 0.022 14.9 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_32 PF13679.6 OAG36563.1 - 0.046 13.7 0.0 0.069 13.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DUF1223 PF06764.11 OAG36564.1 - 1.1e-43 149.6 0.0 4.2e-43 147.7 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1223) ThiS PF02597.20 OAG36566.1 - 9.5e-09 35.8 0.0 8.3e-05 23.2 0.0 2.1 2 0 0 2 2 2 2 ThiS family UDPGP PF01704.18 OAG36567.1 - 8.8e-193 640.6 0.0 8.8e-193 640.6 0.0 1.6 2 0 0 2 2 1 1 UTP--glucose-1-phosphate uridylyltransferase DDHD PF02862.17 OAG36567.1 - 0.011 15.9 4.4 0.026 14.7 4.4 1.6 1 0 0 1 1 1 0 DDHD domain DUF2052 PF09747.9 OAG36567.1 - 0.038 14.1 11.2 0.075 13.2 11.2 1.5 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) RNA_pol_Rpc4 PF05132.14 OAG36567.1 - 0.045 14.2 15.4 0.089 13.2 15.4 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 SpoIIP PF07454.11 OAG36567.1 - 0.05 13.1 12.8 0.083 12.3 12.8 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) CPSF100_C PF13299.6 OAG36567.1 - 0.051 13.8 12.4 0.096 12.9 12.4 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Vfa1 PF08432.10 OAG36567.1 - 0.059 13.7 29.7 0.052 13.9 28.2 1.6 2 0 0 2 2 1 0 AAA-ATPase Vps4-associated protein 1 Rtf2 PF04641.12 OAG36567.1 - 0.066 12.6 26.3 0.17 11.2 26.3 1.7 1 0 0 1 1 1 0 Rtf2 RING-finger DUF3807 PF12720.7 OAG36567.1 - 0.081 13.2 28.6 0.15 12.3 28.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) SspB PF04386.13 OAG36567.1 - 0.11 12.3 9.2 0.24 11.3 9.2 1.5 1 0 0 1 1 1 0 Stringent starvation protein B Neur_chan_memb PF02932.16 OAG36567.1 - 0.29 11.2 6.2 0.49 10.4 6.2 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region BSMAP PF12280.8 OAG36567.1 - 0.36 11.0 4.8 0.71 10.1 4.8 1.5 1 0 0 1 1 1 0 Brain specific membrane anchored protein DUF2126 PF09899.9 OAG36567.1 - 0.87 7.6 5.9 1.5 6.8 5.9 1.3 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) AAA_11 PF13086.6 OAG36567.1 - 1.1 9.0 15.0 2.2 8.0 15.0 1.4 1 0 0 1 1 1 0 AAA domain FAD_oxidored PF12831.7 OAG36567.1 - 1.2 8.5 3.2 42 3.3 4.6 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase LicD PF04991.13 OAG36567.1 - 1.3 9.2 17.5 1.2 9.3 12.5 2.6 2 0 0 2 2 2 0 LicD family DUF2828 PF11443.8 OAG36567.1 - 2 6.4 19.8 3 5.8 19.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) eIF3_subunit PF08597.10 OAG36567.1 - 2.9 7.8 40.1 5.5 6.8 40.1 1.4 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit CDC45 PF02724.14 OAG36567.1 - 3.2 5.9 23.1 5 5.3 23.1 1.2 1 0 0 1 1 1 0 CDC45-like protein YqfQ PF14181.6 OAG36567.1 - 3.2 7.9 19.5 7 6.8 19.5 1.5 1 0 0 1 1 1 0 YqfQ-like protein RR_TM4-6 PF06459.12 OAG36567.1 - 3.4 7.4 24.4 6 6.6 24.4 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 EIIBC-GUT_N PF03612.14 OAG36567.1 - 3.7 7.2 12.4 9.5 5.9 12.4 1.7 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Connexin PF00029.19 OAG36567.1 - 4.1 7.1 19.9 6.6 6.4 19.9 1.3 1 0 0 1 1 1 0 Connexin BORG_CEP PF14957.6 OAG36567.1 - 4.5 8.5 11.1 2.7 9.2 8.8 1.8 2 0 0 2 2 1 0 Cdc42 effector Cellulose_synt PF03552.14 OAG36567.1 - 4.6 5.6 8.7 6.9 5.0 8.7 1.1 1 0 0 1 1 1 0 Cellulose synthase DUF913 PF06025.12 OAG36567.1 - 5.8 5.8 7.4 11 4.9 7.4 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) PcfK PF14058.6 OAG36567.1 - 7 6.9 31.9 9.5 6.5 30.3 2.0 2 0 0 2 2 2 0 PcfK-like protein IHABP4_N PF16174.5 OAG36567.1 - 7.3 7.2 40.9 12 6.4 40.9 1.3 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal SRP-alpha_N PF04086.13 OAG36567.1 - 8.6 6.2 30.9 15 5.4 30.9 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal GCD14 PF08704.10 OAG36567.1 - 8.7 5.9 7.9 20 4.7 7.9 1.6 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit C2 PF00168.30 OAG36568.1 - 7.7e-81 267.1 0.3 3e-20 72.4 0.0 5.6 5 0 0 5 5 5 5 C2 domain SMP_LBD PF17047.5 OAG36568.1 - 0.00067 19.2 0.0 0.0015 18.1 0.0 1.6 1 1 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain MLVIN_C PF18697.1 OAG36568.1 - 0.17 12.0 1.0 2.3 8.4 0.0 2.9 3 0 0 3 3 3 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain ING PF12998.7 OAG36569.1 - 6.1e-16 58.9 3.6 1.5e-15 57.6 3.6 1.7 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 OAG36569.1 - 8.6e-07 28.8 10.4 1.8e-06 27.8 10.4 1.5 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 OAG36569.1 - 0.0033 17.6 4.3 0.013 15.7 4.3 2.1 1 1 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 OAG36569.1 - 0.012 15.7 3.3 0.014 15.6 1.1 2.1 2 0 0 2 2 2 0 PHD-zinc-finger like domain zf-4CXXC_R1 PF10497.9 OAG36569.1 - 0.014 15.6 6.6 0.051 13.8 6.6 2.0 1 0 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 PHD_2 PF13831.6 OAG36569.1 - 0.33 10.5 3.0 0.66 9.6 3.0 1.5 1 0 0 1 1 1 0 PHD-finger zf-RING_2 PF13639.6 OAG36569.1 - 1.2 9.6 6.7 2.3 8.6 6.7 1.5 1 0 0 1 1 1 0 Ring finger domain Hist_deacetyl PF00850.19 OAG36570.1 - 1.2e-78 264.7 0.0 1.6e-78 264.3 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain RNA_pol_Rpc34 PF05158.12 OAG36571.1 - 4.7e-66 223.5 0.0 8e-66 222.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit TPR_1 PF00515.28 OAG36572.1 - 8.6e-46 152.0 19.7 1.3e-05 24.8 0.0 9.6 9 0 0 9 9 9 9 Tetratricopeptide repeat STI1 PF17830.1 OAG36572.1 - 1.7e-38 130.3 8.7 6e-21 74.1 0.8 2.8 3 0 0 3 3 3 2 STI1 domain TPR_2 PF07719.17 OAG36572.1 - 3.1e-37 123.7 20.3 0.00028 20.8 0.0 9.8 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_11 PF13414.6 OAG36572.1 - 1.7e-19 69.2 11.1 0.00062 19.4 0.0 7.8 5 2 2 7 7 7 4 TPR repeat TPR_19 PF14559.6 OAG36572.1 - 4e-14 52.9 6.8 0.021 15.3 0.1 6.2 4 1 1 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 OAG36572.1 - 3.5e-13 48.6 27.2 0.041 14.1 0.0 9.6 10 0 0 10 10 9 4 Tetratricopeptide repeat TPR_9 PF13371.6 OAG36572.1 - 1.3e-12 47.7 1.1 9.9e-05 22.4 0.0 4.9 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 OAG36572.1 - 8.4e-12 45.5 7.2 0.00014 22.5 0.1 6.4 3 2 1 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 OAG36572.1 - 2e-11 43.7 11.9 0.68 10.9 0.1 8.5 5 3 4 9 9 8 4 Tetratricopeptide repeat TPR_17 PF13431.6 OAG36572.1 - 2.4e-10 40.0 4.3 0.038 14.4 0.1 7.4 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_12 PF13424.6 OAG36572.1 - 3.5e-10 40.0 17.4 2.1e-06 27.9 0.0 7.1 6 3 2 8 8 7 3 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 OAG36572.1 - 1.8e-08 34.3 2.7 0.0096 16.0 0.0 5.5 5 1 1 6 6 6 2 Fis1 C-terminal tetratricopeptide repeat TPR_7 PF13176.6 OAG36572.1 - 2.8e-08 33.2 7.2 0.079 13.0 0.0 7.6 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_10 PF13374.6 OAG36572.1 - 1.6e-05 24.6 3.8 0.45 10.5 0.0 6.3 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.6 OAG36572.1 - 4.5e-05 23.8 17.7 0.63 10.8 0.0 8.6 9 0 0 9 9 8 1 Tetratricopeptide repeat ANAPC3 PF12895.7 OAG36572.1 - 0.0037 17.4 10.3 0.27 11.5 0.1 4.2 3 1 1 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 Pyrid_ox_like PF16242.5 OAG36572.1 - 0.11 12.0 0.4 2.4 7.7 0.1 2.3 2 0 0 2 2 2 0 Pyridoxamine 5'-phosphate oxidase like TPR_20 PF14561.6 OAG36572.1 - 0.83 10.0 10.0 2.2 8.7 0.0 4.6 3 2 1 5 5 5 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 OAG36572.1 - 2.8 8.4 8.5 16 6.0 0.6 3.8 4 0 0 4 4 3 0 Alkyl sulfatase dimerisation Na_H_Exchanger PF00999.21 OAG36573.1 - 2.2e-56 191.3 54.8 3.1e-56 190.8 54.8 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF2270 PF10028.9 OAG36575.1 - 0.14 11.7 0.1 0.23 11.0 0.1 1.2 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2270) UBA_4 PF14555.6 OAG36577.1 - 1.6e-10 40.6 0.0 3.9e-10 39.4 0.0 1.7 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 OAG36577.1 - 4.4e-10 39.6 0.0 1e-09 38.5 0.0 1.7 1 0 0 1 1 1 1 UBX domain Pan3_PK PF18101.1 OAG36578.1 - 3.7e-64 214.8 0.6 5.6e-64 214.3 0.6 1.3 1 0 0 1 1 1 1 Pan3 Pseudokinase domain Pkinase PF00069.25 OAG36578.1 - 1.4e-07 31.2 0.0 2.3e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG36578.1 - 0.0057 16.0 0.0 0.0092 15.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PAM2 PF07145.15 OAG36578.1 - 6.6 6.7 6.7 2.1 8.2 0.2 2.8 3 0 0 3 3 3 0 Ataxin-2 C-terminal region LSM PF01423.22 OAG36579.1 - 1.8e-20 72.4 0.1 2.3e-20 72.0 0.1 1.1 1 0 0 1 1 1 1 LSM domain FoP_duplication PF13865.6 OAG36579.1 - 0.0077 16.8 8.3 0.011 16.3 8.3 1.3 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 DUF150_C PF17384.2 OAG36579.1 - 0.075 13.2 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 RimP C-terminal SH3 domain RhlB PF12300.8 OAG36579.1 - 1 9.5 10.0 1.7 8.8 10.0 1.3 1 0 0 1 1 1 0 ATP-dependent RNA helicase RhlB Zn_clus PF00172.18 OAG36580.1 - 0.031 14.4 9.7 0.066 13.3 9.7 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Dioxygenase_C PF00775.21 OAG36581.1 - 3.9e-42 143.7 0.0 8.5e-42 142.6 0.0 1.5 2 0 0 2 2 2 1 Dioxygenase Dioxygenase_N PF04444.14 OAG36581.1 - 4.9e-32 109.6 0.0 9.9e-32 108.6 0.0 1.5 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 OAG36581.1 - 0.019 15.2 0.0 0.1 12.9 0.0 2.1 1 1 0 1 1 1 0 Carboxypeptidase regulatory-like domain DUF824 PF05688.11 OAG36581.1 - 0.079 12.8 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 Salmonella repeat of unknown function (DUF824) Big_1 PF02369.16 OAG36581.1 - 0.17 11.9 0.0 0.46 10.5 0.0 1.7 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 1) GFA PF04828.14 OAG36582.1 - 9.2e-11 41.9 1.1 1.5e-09 38.0 0.0 2.5 2 1 1 3 3 3 2 Glutathione-dependent formaldehyde-activating enzyme Methyltransf_25 PF13649.6 OAG36583.1 - 1.7e-07 31.8 0.0 6.1e-07 30.1 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG36583.1 - 1.8e-06 27.8 0.0 2.4e-05 24.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG36583.1 - 3.5e-06 27.7 0.0 2.2e-05 25.1 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG36583.1 - 3.9e-06 27.4 0.0 1.2e-05 25.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain CheR PF01739.18 OAG36583.1 - 0.002 17.7 0.0 0.0047 16.4 0.0 1.6 2 0 0 2 2 2 1 CheR methyltransferase, SAM binding domain Methyltransf_23 PF13489.6 OAG36583.1 - 0.0029 17.4 0.0 0.0041 17.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAG36583.1 - 0.0036 16.7 0.0 0.011 15.0 0.0 1.8 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 OAG36583.1 - 0.024 14.2 0.0 0.043 13.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain NAS PF03059.16 OAG36583.1 - 0.19 11.1 0.0 0.32 10.3 0.0 1.3 1 0 0 1 1 1 0 Nicotianamine synthase protein Methyltransf_23 PF13489.6 OAG36584.1 - 3.2e-11 43.3 0.1 4.7e-11 42.8 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG36584.1 - 8e-08 32.9 0.1 2.6e-07 31.3 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG36584.1 - 1.3e-05 25.7 0.0 2.8e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 OAG36584.1 - 7.9e-05 22.8 0.0 0.00014 22.1 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_12 PF08242.12 OAG36584.1 - 0.00012 22.8 0.0 0.00032 21.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG36584.1 - 0.00015 21.6 0.0 0.00054 19.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 OAG36584.1 - 0.0029 16.9 0.0 0.0062 15.9 0.0 1.5 2 0 0 2 2 2 1 O-methyltransferase domain Methyltransf_4 PF02390.17 OAG36584.1 - 0.033 13.7 0.0 0.055 12.9 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Waikav_capsid_1 PF12264.8 OAG36584.1 - 0.075 12.5 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Waikavirus capsid protein 1 Methyltransf_32 PF13679.6 OAG36584.1 - 0.11 12.5 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 OAG36584.1 - 0.17 11.5 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain MARVEL PF01284.23 OAG36585.1 - 9.4e-07 28.9 10.0 9.4e-07 28.9 10.0 1.5 1 1 0 1 1 1 1 Membrane-associating domain MFS_1 PF07690.16 OAG36586.1 - 1.6e-09 37.1 16.2 0.00031 19.8 5.2 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily TatC PF00902.18 OAG36586.1 - 0.28 11.0 16.1 0.02 14.7 2.7 3.1 1 1 1 2 2 2 0 Sec-independent protein translocase protein (TatC) S_4TM PF18159.1 OAG36586.1 - 2.2 7.5 6.2 2.2 7.5 0.0 2.9 3 1 0 3 3 3 0 SMODS-associating 4TM effector domain FMO-like PF00743.19 OAG36587.1 - 1.9e-40 138.8 0.0 4.3e-21 74.9 0.0 3.2 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OAG36587.1 - 1.1e-14 54.4 0.0 5.3e-10 39.0 0.0 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAG36587.1 - 9.1e-12 44.8 0.0 4.3e-10 39.3 0.0 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAG36587.1 - 1.1e-10 41.6 3.2 3e-07 30.3 1.6 3.1 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAG36587.1 - 2.9e-08 33.8 0.4 1.6e-07 31.4 0.0 2.3 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 OAG36587.1 - 4.6e-08 33.2 3.0 3.1e-05 24.0 0.2 3.8 4 0 0 4 4 4 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 OAG36587.1 - 3.9e-06 26.2 0.8 0.00063 19.0 0.0 2.5 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Amino_oxidase PF01593.24 OAG36587.1 - 2.2e-05 24.0 0.0 0.021 14.1 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 OAG36587.1 - 0.00015 21.2 0.0 0.00032 20.2 0.0 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 OAG36587.1 - 0.00066 20.2 2.8 0.018 15.6 0.5 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 OAG36587.1 - 0.0012 19.0 0.1 0.25 11.4 0.2 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.17 OAG36587.1 - 0.0028 16.9 0.2 0.0055 16.0 0.2 1.5 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 OAG36587.1 - 0.0037 16.0 0.8 0.014 14.2 0.8 1.9 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 OAG36587.1 - 0.018 14.1 0.5 0.035 13.2 0.5 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_binding_3 PF01494.19 OAG36587.1 - 0.019 14.2 0.5 0.039 13.2 0.5 1.5 1 0 0 1 1 1 0 FAD binding domain 3HCDH_N PF02737.18 OAG36587.1 - 0.02 14.8 1.0 0.034 14.0 0.4 1.7 2 0 0 2 2 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 OAG36587.1 - 0.023 13.8 1.5 0.03 13.4 0.6 1.6 2 0 0 2 2 2 0 FAD binding domain ApbA PF02558.16 OAG36587.1 - 0.11 12.1 1.7 0.24 11.0 1.7 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.23 OAG36587.1 - 0.2 11.6 1.8 4.3 7.3 0.4 2.4 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus MFS_1 PF07690.16 OAG36588.1 - 4.8e-41 140.8 28.6 5e-37 127.6 13.7 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 OAG36588.1 - 2e-06 27.3 0.8 4.8e-06 26.1 0.8 1.6 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB TauD PF02668.16 OAG36589.1 - 3.4e-63 213.9 0.1 4.3e-63 213.6 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Glyco_trans_2_3 PF13632.6 OAG36590.1 - 5.5e-19 68.8 0.2 5.5e-19 68.8 0.2 2.0 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 OAG36590.1 - 8.2e-16 58.6 0.0 4.4e-15 56.2 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 OAG36590.1 - 1.9e-14 53.8 0.0 3.2e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Cellulose_synt PF03552.14 OAG36590.1 - 2.5e-12 46.1 0.2 3.3e-06 25.9 0.2 2.9 1 1 2 3 3 3 2 Cellulose synthase Glyco_transf_21 PF13506.6 OAG36590.1 - 7e-12 45.2 0.0 1.4e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 21 Chitin_synth_2 PF03142.15 OAG36590.1 - 0.0078 14.9 0.9 0.083 11.5 0.2 2.2 2 0 0 2 2 2 1 Chitin synthase MFS_1 PF07690.16 OAG36591.1 - 2.9e-24 85.6 42.3 2.9e-24 85.6 42.3 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily TPPK_C PF12555.8 OAG36591.1 - 0.52 10.4 9.9 5.3 7.2 2.4 3.3 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal Sugar_tr PF00083.24 OAG36593.1 - 2.9e-84 283.5 17.6 3.3e-84 283.3 17.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG36593.1 - 5.9e-24 84.6 29.1 7.6e-24 84.3 25.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 OAG36593.1 - 1.7e-06 27.6 2.4 1.7e-06 27.6 2.4 2.2 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 OAG36593.1 - 0.055 11.8 10.1 0.056 11.7 5.5 2.8 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Pyr_redox_3 PF13738.6 OAG36594.1 - 1.4e-13 50.8 0.0 3.4e-12 46.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 OAG36594.1 - 2.9e-12 45.8 0.0 1.5e-11 43.4 0.0 2.0 3 0 0 3 3 3 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 OAG36594.1 - 4.8e-08 32.5 0.0 4.4e-07 29.4 0.0 2.0 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 OAG36594.1 - 3e-07 30.0 0.0 0.00028 20.2 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAG36594.1 - 0.036 14.1 0.0 9.9 6.1 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding Amino_oxidase PF01593.24 OAG36594.1 - 0.054 12.8 0.0 4.4 6.5 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Peptidase_S28 PF05577.12 OAG36595.1 - 2.4e-31 109.0 0.0 4.3e-31 108.2 0.0 1.3 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S9 PF00326.21 OAG36595.1 - 0.0035 16.9 0.3 0.011 15.2 0.0 2.0 3 0 0 3 3 3 1 Prolyl oligopeptidase family Methyltransf_23 PF13489.6 OAG36596.1 - 5.9e-22 78.2 0.0 1.2e-21 77.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG36596.1 - 1.5e-14 54.4 0.0 1.6e-13 51.2 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG36596.1 - 3.4e-13 50.0 0.0 1.2e-12 48.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG36596.1 - 8.8e-10 38.6 0.0 1.6e-08 34.5 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG36596.1 - 6.7e-09 36.4 0.0 8.5e-08 32.9 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 OAG36596.1 - 2.9e-05 23.6 0.0 4.5e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 OAG36596.1 - 0.00016 21.3 0.0 0.00068 19.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.18 OAG36596.1 - 0.0041 16.4 0.0 0.008 15.5 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_4 PF02390.17 OAG36596.1 - 0.01 15.3 0.0 0.058 12.9 0.0 2.1 2 0 0 2 2 2 0 Putative methyltransferase Ubie_methyltran PF01209.18 OAG36596.1 - 0.012 14.9 0.0 0.077 12.3 0.0 2.0 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family CMAS PF02353.20 OAG36596.1 - 0.022 14.0 0.0 0.042 13.2 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_16 PF10294.9 OAG36596.1 - 0.18 11.5 0.0 0.38 10.5 0.0 1.6 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_2 PF00891.18 OAG36597.1 - 1.8e-26 92.8 0.0 2.9e-26 92.1 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_33 PF10017.9 OAG36597.1 - 0.057 12.6 0.0 7.9 5.5 0.0 2.7 2 1 0 3 3 3 0 Histidine-specific methyltransferase, SAM-dependent HTH_IclR PF09339.10 OAG36597.1 - 0.66 9.8 0.1 0.66 9.8 0.1 2.7 4 0 0 4 4 4 0 IclR helix-turn-helix domain Acetyltransf_1 PF00583.25 OAG36599.1 - 6.6e-10 39.2 0.0 1e-09 38.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OAG36599.1 - 1.3e-05 25.6 0.0 2.1e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OAG36599.1 - 0.00092 19.2 0.0 0.0016 18.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAG36599.1 - 0.056 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein DUF1690 PF07956.11 OAG36600.1 - 6.9e-38 130.2 8.2 1.1e-37 129.5 8.2 1.3 1 1 0 1 1 1 1 Protein of Unknown function (DUF1690) Apolipoprotein PF01442.18 OAG36600.1 - 0.0046 16.9 4.1 0.0073 16.2 4.1 1.3 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Rootletin PF15035.6 OAG36600.1 - 0.02 14.9 1.8 0.02 14.9 1.8 2.0 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion FAM184 PF15665.5 OAG36600.1 - 0.9 9.3 9.5 0.17 11.7 1.0 2.4 2 1 0 2 2 2 0 Family with sequence similarity 184, A and B FMO-like PF00743.19 OAG36601.1 - 6e-39 133.9 0.0 1.5e-27 96.3 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OAG36601.1 - 2.8e-13 49.8 0.3 8e-12 45.0 0.2 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAG36601.1 - 3e-11 43.1 0.0 2.3e-10 40.2 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG36601.1 - 1.9e-09 37.1 0.0 3.7e-07 29.6 0.0 2.5 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 OAG36601.1 - 1.6e-06 28.2 0.0 1.2e-05 25.3 0.0 2.1 1 1 0 1 1 1 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 OAG36601.1 - 0.0001 22.5 0.0 0.00024 21.3 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAG36601.1 - 0.00037 20.2 0.0 0.062 12.9 0.0 2.6 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 OAG36601.1 - 0.043 14.4 0.4 0.59 10.7 0.0 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Pkinase PF00069.25 OAG36603.1 - 1.6e-68 230.9 0.0 1.2e-67 228.0 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Fungal_KA1 PF16797.5 OAG36603.1 - 3.4e-38 130.0 0.2 3.4e-38 130.0 0.2 2.1 3 0 0 3 3 3 1 Fungal kinase associated-1 domain Pkinase_Tyr PF07714.17 OAG36603.1 - 3.1e-37 128.3 0.0 2.1e-35 122.3 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OAG36603.1 - 0.0001 21.4 0.0 0.00024 20.2 0.0 1.6 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 OAG36603.1 - 0.0062 15.9 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OAG36603.1 - 0.0085 15.5 0.0 0.019 14.3 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OAG36603.1 - 0.012 15.5 0.0 0.061 13.2 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 OAG36603.1 - 0.018 14.6 0.0 0.036 13.7 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Fasciclin PF02469.22 OAG36604.1 - 3.5e-45 153.3 0.0 2e-23 83.0 0.0 2.5 3 0 0 3 3 3 2 Fasciclin domain DUF1348 PF07080.11 OAG36605.1 - 2.2e-53 179.6 2.0 2.8e-53 179.3 2.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) 30K_MP_C_Ter PF11330.8 OAG36605.1 - 0.051 12.9 0.7 0.071 12.4 0.7 1.2 1 0 0 1 1 1 0 C-Terminal of 30K viral movement proteins Redoxin PF08534.10 OAG36606.1 - 2.1e-35 121.6 0.0 2.4e-35 121.4 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 OAG36606.1 - 6.3e-11 42.3 0.0 8.3e-11 41.9 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family bZIP_1 PF00170.21 OAG36607.1 - 2.3e-06 27.6 7.4 2.3e-06 27.6 7.4 2.1 2 1 1 3 3 3 1 bZIP transcription factor bZIP_2 PF07716.15 OAG36607.1 - 0.0056 16.7 6.1 0.0056 16.7 6.1 2.6 2 1 1 3 3 3 1 Basic region leucine zipper SHE3 PF17078.5 OAG36607.1 - 0.05 13.3 1.8 0.089 12.5 1.8 1.3 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 DUF4094 PF13334.6 OAG36607.1 - 0.19 12.1 1.0 0.33 11.4 1.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) CLZ PF16526.5 OAG36607.1 - 0.37 11.2 4.3 0.43 11.0 1.4 2.3 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF3886 PF13025.6 OAG36607.1 - 3.7 7.8 7.0 16 5.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3886) Fungal_trans_2 PF11951.8 OAG36608.1 - 3e-12 46.0 0.3 5e-12 45.3 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain POP1 PF06978.11 OAG36609.1 - 1.9e-68 230.5 22.2 1.9e-68 230.5 22.2 2.4 3 0 0 3 3 3 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 OAG36609.1 - 4.2e-29 100.7 0.7 4.2e-29 100.7 0.7 2.3 2 0 0 2 2 2 1 POPLD (NUC188) domain GCV_T PF01571.21 OAG36609.1 - 0.11 11.9 0.0 0.24 10.7 0.0 1.5 1 0 0 1 1 1 0 Aminomethyltransferase folate-binding domain NAD_binding_6 PF08030.12 OAG36610.1 - 1.3e-18 67.6 0.0 3.5e-18 66.2 0.0 1.7 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 OAG36610.1 - 1.4e-18 67.2 11.6 1.4e-18 67.2 11.6 3.0 3 0 0 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 OAG36610.1 - 2.2e-13 50.3 0.0 5.3e-13 49.0 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 OAG36610.1 - 2.7e-05 24.8 0.0 0.25 12.0 0.0 2.4 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain DUF4405 PF14358.6 OAG36610.1 - 1.3 9.6 19.1 0.1 13.2 1.7 3.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4405) Pro_isomerase PF00160.21 OAG36611.1 - 4.1e-54 183.1 0.0 4.6e-54 183.0 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ABM PF03992.16 OAG36612.1 - 0.04 14.0 0.1 0.36 11.0 0.1 2.3 2 1 0 2 2 2 0 Antibiotic biosynthesis monooxygenase Carboxyl_trans PF01039.22 OAG36613.1 - 1.4e-139 465.9 0.1 2e-139 465.5 0.1 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain Phage_tail_S PF05069.13 OAG36613.1 - 0.12 12.2 1.6 1.3 8.9 1.5 2.3 2 0 0 2 2 2 0 Phage virion morphogenesis family ECH_1 PF00378.20 OAG36613.1 - 0.15 11.4 0.0 0.15 11.4 0.0 2.0 3 0 0 3 3 3 0 Enoyl-CoA hydratase/isomerase Ras PF00071.22 OAG36614.1 - 1.7e-51 174.0 0.0 2.1e-51 173.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAG36614.1 - 1.3e-18 67.4 0.0 1.8e-18 66.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAG36614.1 - 5.5e-10 39.0 0.0 6.3e-10 38.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OAG36614.1 - 2.8e-05 23.8 0.1 0.00029 20.4 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OAG36614.1 - 0.00038 20.5 0.0 0.00057 20.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OAG36614.1 - 0.0056 16.6 0.1 1.5 8.7 0.1 2.2 1 1 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 OAG36614.1 - 0.074 13.3 0.3 0.38 11.0 0.1 2.2 2 1 0 2 2 2 0 AAA domain DUF3425 PF11905.8 OAG36615.1 - 9.5e-17 61.1 0.0 1.8e-16 60.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 OAG36615.1 - 0.02 15.0 7.8 0.036 14.2 7.8 1.3 1 0 0 1 1 1 0 bZIP transcription factor bZIP_2 PF07716.15 OAG36615.1 - 0.34 11.0 8.8 0.65 10.1 8.8 1.4 1 0 0 1 1 1 0 Basic region leucine zipper PHD PF00628.29 OAG36616.1 - 1e-09 38.1 0.9 2.1e-09 37.1 0.9 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 OAG36616.1 - 0.0068 15.9 1.7 0.011 15.2 1.7 1.4 1 0 0 1 1 1 1 PHD-finger zf-CW PF07496.15 OAG36616.1 - 0.031 14.3 0.4 0.071 13.1 0.4 1.6 1 0 0 1 1 1 0 CW-type Zinc Finger UIM PF02809.20 OAG36616.1 - 0.044 13.7 3.3 0.12 12.3 3.3 1.8 1 0 0 1 1 1 0 Ubiquitin interaction motif DUF1752 PF08550.10 OAG36617.1 - 0.00076 19.3 1.0 0.0022 17.8 1.0 1.9 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) adh_short_C2 PF13561.6 OAG36618.1 - 6.5e-54 183.0 0.2 1.3e-53 182.0 0.2 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG36618.1 - 8e-38 129.9 1.1 1.7e-37 128.8 1.1 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG36618.1 - 4.7e-13 49.4 0.3 6.7e-13 48.9 0.3 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG36618.1 - 0.00017 21.1 0.0 0.00022 20.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAG36618.1 - 0.1 11.9 0.0 11 5.3 0.0 2.1 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase DUF4396 PF14342.6 OAG36619.1 - 0.0033 17.8 1.9 0.0061 16.9 1.9 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4396) CPSase_L_D2 PF02786.17 OAG36622.1 - 1.8e-77 259.6 0.0 3e-77 258.9 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.19 OAG36622.1 - 9.9e-39 131.8 0.0 2.8e-38 130.3 0.0 1.8 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_carb_N PF00289.22 OAG36622.1 - 8.2e-37 126.1 0.0 1.5e-36 125.2 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_lipoyl PF00364.22 OAG36622.1 - 4.3e-14 52.1 0.9 9.8e-14 51.0 0.9 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 OAG36622.1 - 8e-11 41.9 0.0 1.6e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 OAG36622.1 - 5.8e-09 35.8 0.0 1.1e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 OAG36622.1 - 2.7e-05 24.3 0.0 5.1e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 OAG36622.1 - 0.00015 21.4 0.0 0.00078 19.1 0.0 2.2 2 1 0 2 2 2 1 RimK-like ATP-grasp domain GARS_A PF01071.19 OAG36622.1 - 0.00016 21.5 0.0 0.00025 20.9 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Biotin_lipoyl_2 PF13533.6 OAG36622.1 - 0.0034 17.2 0.0 0.015 15.1 0.0 2.1 1 1 1 2 2 2 1 Biotin-lipoyl like ATP-grasp_4 PF13535.6 OAG36622.1 - 0.018 14.6 0.0 0.039 13.5 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain ATP-grasp_5 PF13549.6 OAG36622.1 - 0.032 13.7 0.0 0.18 11.3 0.0 2.1 1 1 0 1 1 1 0 ATP-grasp domain ATPgrasp_Ter PF15632.6 OAG36622.1 - 0.037 13.8 0.0 0.1 12.4 0.0 1.7 2 0 0 2 2 2 0 ATP-grasp in the biosynthetic pathway with Ter operon ATPgrasp_ST PF14397.6 OAG36622.1 - 0.13 11.5 0.0 0.27 10.4 0.0 1.4 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp DUF3450 PF11932.8 OAG36623.1 - 0.024 14.0 0.7 0.05 12.9 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) ATG16 PF08614.11 OAG36623.1 - 0.056 13.7 4.8 0.17 12.1 4.8 1.9 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) HrpB7 PF09486.10 OAG36623.1 - 0.34 11.3 7.9 0.047 14.1 2.5 2.1 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) WD40 PF00400.32 OAG36624.1 - 3e-29 100.6 17.8 1.9e-08 34.8 0.0 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG36624.1 - 7e-11 42.3 0.1 0.0016 18.7 0.2 4.8 2 2 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Me-amine-dh_H PF06433.11 OAG36624.1 - 7e-05 21.9 0.0 0.0027 16.6 0.0 2.3 2 0 0 2 2 2 1 Methylamine dehydrogenase heavy chain (MADH) Ge1_WD40 PF16529.5 OAG36624.1 - 0.00044 19.3 0.0 0.0098 14.9 0.0 2.4 3 0 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 OAG36624.1 - 0.00064 18.5 1.0 0.015 14.0 0.0 2.7 3 1 0 3 3 3 1 Nucleoporin Nup120/160 Proteasome_A_N PF10584.9 OAG36624.1 - 0.19 11.5 0.2 0.54 10.0 0.0 1.9 2 0 0 2 2 2 0 Proteasome subunit A N-terminal signature TRAM_LAG1_CLN8 PF03798.16 OAG36625.1 - 1.8e-44 151.9 20.5 1.8e-44 151.9 20.5 2.1 2 1 0 2 2 2 1 TLC domain TRAM1 PF08390.11 OAG36625.1 - 5.6e-19 67.6 0.3 5.6e-19 67.6 0.3 2.2 2 0 0 2 2 2 1 TRAM1-like protein Macoilin PF09726.9 OAG36625.1 - 6 5.3 6.4 9.3 4.7 6.4 1.2 1 0 0 1 1 1 0 Macoilin family AAA PF00004.29 OAG36626.1 - 6.6e-41 139.8 0.0 1.2e-40 138.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OAG36626.1 - 1.4e-11 44.0 0.7 2.8e-11 43.0 0.7 1.5 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 OAG36626.1 - 1.3e-09 37.9 0.1 2.4e-09 37.0 0.1 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 OAG36626.1 - 5e-06 26.7 0.0 1.1e-05 25.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 OAG36626.1 - 5.2e-06 26.8 0.2 0.0059 16.9 0.2 2.6 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 OAG36626.1 - 1.3e-05 24.5 0.0 2.1e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 OAG36626.1 - 9.8e-05 22.4 0.1 0.00028 20.9 0.1 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OAG36626.1 - 0.00024 21.5 0.3 0.002 18.6 0.2 2.2 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 OAG36626.1 - 0.00025 20.8 0.0 0.00052 19.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 OAG36626.1 - 0.0024 18.4 0.0 0.0067 17.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 OAG36626.1 - 0.0034 17.6 0.5 0.0076 16.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.11 OAG36626.1 - 0.0097 15.8 0.0 0.041 13.8 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 OAG36626.1 - 0.011 15.8 0.0 0.027 14.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 OAG36626.1 - 0.016 14.9 0.0 0.04 13.7 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.13 OAG36626.1 - 0.018 14.3 0.1 0.058 12.6 0.1 1.6 1 1 0 1 1 1 0 TIP49 P-loop domain AAA_14 PF13173.6 OAG36626.1 - 0.018 15.1 0.0 0.037 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 OAG36626.1 - 0.021 14.2 0.1 0.57 9.5 0.1 2.2 1 1 0 2 2 2 0 KaiC NACHT PF05729.12 OAG36626.1 - 0.021 14.7 0.1 0.63 9.9 0.1 2.5 1 1 1 2 2 2 0 NACHT domain RNA_helicase PF00910.22 OAG36626.1 - 0.048 14.1 0.0 0.099 13.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.21 OAG36626.1 - 0.058 12.8 0.1 0.12 11.7 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 OAG36626.1 - 0.065 12.5 0.0 0.18 11.0 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin PhoH PF02562.16 OAG36626.1 - 0.087 12.3 0.3 0.51 9.7 0.1 2.0 2 0 0 2 2 2 0 PhoH-like protein Prot_ATP_OB_N PF17758.1 OAG36626.1 - 0.12 12.0 0.5 1 9.0 0.0 2.4 2 0 0 2 2 2 0 Proteasomal ATPase OB N-terminal domain AAA_25 PF13481.6 OAG36626.1 - 0.13 11.8 1.2 0.66 9.5 0.4 2.2 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.6 OAG36626.1 - 0.13 11.9 0.3 0.3 10.8 0.3 1.7 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.9 OAG36626.1 - 0.16 11.2 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 OAG36626.1 - 0.2 11.1 0.1 0.52 9.8 0.1 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region UQ_con PF00179.26 OAG36627.1 - 2.4e-42 143.9 0.0 3.2e-42 143.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.10 OAG36627.1 - 2.4e-05 24.0 0.1 4.8e-05 23.1 0.1 1.5 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain GGA_N-GAT PF18308.1 OAG36627.1 - 0.0059 16.2 0.1 0.013 15.1 0.1 1.5 1 0 0 1 1 1 1 GGA N-GAT domain Prok-E2_B PF14461.6 OAG36627.1 - 0.0075 16.0 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 OAG36627.1 - 0.12 12.7 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 RWD domain Cyclin_C_2 PF16899.5 OAG36628.1 - 9.1e-33 112.8 0.1 4.3e-26 91.3 0.0 2.4 2 0 0 2 2 2 2 Cyclin C-terminal domain Cyclin_N PF00134.23 OAG36628.1 - 1.3e-06 28.2 0.0 2.9e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain GFO_IDH_MocA PF01408.22 OAG36629.1 - 4e-24 85.7 0.0 6.6e-24 85.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 OAG36629.1 - 5.7e-14 52.1 0.0 1.2e-13 51.1 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 OAG36629.1 - 0.00018 22.1 0.3 0.00037 21.1 0.3 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DUF4350 PF14258.6 OAG36629.1 - 0.014 15.8 0.0 0.18 12.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4350) DapB_N PF01113.20 OAG36629.1 - 0.046 13.9 0.0 0.1 12.7 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus CBP_BcsQ PF06564.12 OAG36629.1 - 0.16 11.4 0.1 0.25 10.8 0.1 1.2 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsQ Asp-B-Hydro_N PF05279.11 OAG36630.1 - 2.1 8.3 10.5 4 7.5 10.5 1.4 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region AA_permease_2 PF13520.6 OAG36631.1 - 5.3e-64 216.6 38.7 7.2e-64 216.2 38.7 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAG36631.1 - 4.7e-26 91.4 23.6 4.7e-26 91.4 23.6 2.1 2 0 0 2 2 2 1 Amino acid permease NADHdeh_related PF10125.9 OAG36631.1 - 0.0075 15.7 4.9 0.017 14.5 4.9 1.6 1 0 0 1 1 1 1 NADH dehydrogenase I, subunit N related protein CCB1 PF12046.8 OAG36631.1 - 0.036 13.4 0.1 0.096 12.0 0.1 1.7 1 0 0 1 1 1 0 Cofactor assembly of complex C subunit B Hydrophobin_2 PF06766.11 OAG36632.1 - 5.9 6.9 6.2 2.1 8.4 0.3 2.9 3 0 0 3 3 3 0 Fungal hydrophobin MreB_Mbl PF06723.13 OAG36633.1 - 0.016 14.1 0.1 0.035 12.9 0.1 1.5 1 0 0 1 1 1 0 MreB/Mbl protein Phage_lysozyme2 PF18013.1 OAG36634.1 - 0.022 14.8 0.0 0.049 13.6 0.0 1.6 1 0 0 1 1 1 0 Phage tail lysozyme Pyr_redox_2 PF07992.14 OAG36635.1 - 4.2e-47 160.8 1.8 7.1e-47 160.0 1.8 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAG36635.1 - 5.3e-18 65.4 10.0 3.9e-17 62.6 0.1 3.5 5 0 0 5 5 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 OAG36635.1 - 1.7e-16 60.4 0.1 6.6e-16 58.5 0.0 2.0 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_3 PF13738.6 OAG36635.1 - 3.3e-10 39.7 0.4 4.6e-07 29.4 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 OAG36635.1 - 1.2e-06 28.9 1.3 0.0037 17.7 0.1 2.9 2 1 0 2 2 2 2 Putative NAD(P)-binding Lycopene_cycl PF05834.12 OAG36635.1 - 5e-06 25.8 2.2 0.015 14.4 0.1 3.2 2 1 1 3 3 3 2 Lycopene cyclase protein 3HCDH_N PF02737.18 OAG36635.1 - 1.1e-05 25.3 3.2 0.0071 16.2 0.1 2.5 3 0 0 3 3 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.22 OAG36635.1 - 4.4e-05 22.7 6.3 0.026 13.6 0.4 2.6 2 1 0 2 2 2 2 Glucose inhibited division protein A K_oxygenase PF13434.6 OAG36635.1 - 0.00014 21.1 0.3 0.0011 18.1 0.1 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) 2-Hacid_dh_C PF02826.19 OAG36635.1 - 0.00016 21.1 0.0 0.056 12.8 0.0 2.9 3 0 0 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HI0933_like PF03486.14 OAG36635.1 - 0.00032 19.5 4.9 0.036 12.8 0.0 3.1 3 0 0 3 3 3 2 HI0933-like protein AlaDh_PNT_C PF01262.21 OAG36635.1 - 0.00065 19.0 1.6 0.0075 15.6 0.1 2.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 OAG36635.1 - 0.00081 18.6 4.1 0.53 9.3 0.1 3.3 3 0 0 3 3 3 2 FAD binding domain FAD_binding_3 PF01494.19 OAG36635.1 - 0.0011 18.3 2.5 0.11 11.8 0.2 2.3 2 0 0 2 2 2 2 FAD binding domain ThiF PF00899.21 OAG36635.1 - 0.0082 15.5 0.3 2.9 7.2 0.1 2.6 3 0 0 3 3 3 1 ThiF family XdhC_C PF13478.6 OAG36635.1 - 0.013 16.0 0.0 5.6 7.5 0.0 2.5 2 0 0 2 2 2 0 XdhC Rossmann domain TrkA_N PF02254.18 OAG36635.1 - 0.014 15.7 2.3 4.2 7.7 0.1 3.0 3 0 0 3 3 2 0 TrkA-N domain F420_oxidored PF03807.17 OAG36635.1 - 0.015 15.9 0.1 2 9.1 0.0 2.8 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Thi4 PF01946.17 OAG36635.1 - 0.029 13.6 0.3 0.15 11.3 0.0 2.1 2 0 0 2 2 2 0 Thi4 family DFP PF04127.15 OAG36635.1 - 0.038 13.8 0.6 0.098 12.5 0.1 1.9 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein Shikimate_DH PF01488.20 OAG36635.1 - 0.045 13.8 0.2 37 4.4 0.0 3.3 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.14 OAG36635.1 - 0.046 13.3 0.1 1.2 8.7 0.0 2.5 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_oxidored PF12831.7 OAG36635.1 - 0.062 12.6 3.9 0.37 10.1 0.1 2.7 2 1 1 3 3 3 0 FAD dependent oxidoreductase Rossmann-like PF10727.9 OAG36635.1 - 0.13 12.1 2.6 2.9 7.8 0.1 3.3 3 0 0 3 3 3 0 Rossmann-like domain DAO PF01266.24 OAG36635.1 - 0.39 10.3 9.4 6.7 6.2 2.2 3.8 3 1 0 3 3 3 0 FAD dependent oxidoreductase Aspzincin_M35 PF14521.6 OAG36636.1 - 0.002 18.7 0.1 0.054 14.0 0.0 2.5 2 0 0 2 2 2 1 Lysine-specific metallo-endopeptidase FAD_binding_6 PF00970.24 OAG36637.1 - 7e-10 39.1 0.0 1.7e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 OAG36637.1 - 5e-09 36.8 0.0 0.00011 22.8 0.0 2.6 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 OAG36637.1 - 0.074 13.2 0.0 0.24 11.5 0.0 1.8 2 0 0 2 2 2 0 Ferric reductase NAD binding domain AMP-binding PF00501.28 OAG36638.1 - 6.5e-72 242.4 0.0 8.1e-72 242.1 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG36638.1 - 4.1e-15 56.5 0.1 9.6e-15 55.3 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain CH PF00307.31 OAG36639.1 - 3.2e-47 159.2 0.0 1.1e-22 80.3 0.0 2.7 3 0 0 3 3 3 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.10 OAG36639.1 - 1.6e-25 89.0 3.2 3.8e-25 87.8 0.1 2.7 3 0 0 3 3 2 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.8 OAG36639.1 - 1.1e-10 41.2 0.3 1.4e-06 28.0 0.0 3.2 3 0 0 3 3 3 2 CAMSAP CH domain EF-hand_6 PF13405.6 OAG36639.1 - 8.6e-06 25.3 0.1 4.2e-05 23.2 0.1 2.3 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.32 OAG36639.1 - 0.00026 20.3 0.1 0.00096 18.5 0.0 2.1 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 OAG36639.1 - 0.0049 16.7 0.0 0.016 15.1 0.0 1.9 1 0 0 1 1 1 1 EF-hand domain pair DUF1943 PF09172.11 OAG36639.1 - 0.0096 15.2 0.2 0.015 14.6 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1943) Spectrin PF00435.21 OAG36639.1 - 0.017 15.6 6.0 1.3 9.6 0.1 2.8 2 0 0 2 2 2 0 Spectrin repeat EF-hand_7 PF13499.6 OAG36639.1 - 0.035 14.6 2.4 0.26 11.8 0.8 3.1 2 1 0 2 2 2 0 EF-hand domain pair NADH-UOR_E PF16514.5 OAG36639.1 - 0.093 13.1 0.1 0.6 10.5 0.1 2.5 1 1 0 1 1 1 0 putative NADH-ubiquinone oxidoreductase chain E zf-RRPl_C4 PF17026.5 OAG36639.1 - 0.18 11.9 0.0 0.49 10.5 0.0 1.7 1 0 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type DUF4508 PF14969.6 OAG36639.1 - 0.4 11.0 3.5 6.4 7.1 0.4 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4508) FUSC PF04632.12 OAG36639.1 - 0.91 8.0 3.7 1.3 7.4 3.7 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family HAD_2 PF13419.6 OAG36640.1 - 1.9e-18 67.2 0.0 2.9e-18 66.6 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Glyco_transf_8 PF01501.20 OAG36640.1 - 1.3e-11 44.5 0.0 2.4e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 8 Hydrolase PF00702.26 OAG36640.1 - 1.8e-10 41.5 0.0 6.6e-10 39.6 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 OAG36640.1 - 0.0012 19.3 0.0 0.003 18.0 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Nucleotid_trans PF03407.16 OAG36640.1 - 0.0028 17.6 0.3 0.0068 16.4 0.2 1.6 2 0 0 2 2 2 1 Nucleotide-diphospho-sugar transferase Hydrolase_like PF13242.6 OAG36640.1 - 0.0032 17.5 0.0 0.0065 16.5 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like zf-TFIIB PF13453.6 OAG36640.1 - 0.056 12.8 0.1 0.2 11.0 0.1 2.0 2 0 0 2 2 2 0 Transcription factor zinc-finger GFO_IDH_MocA PF01408.22 OAG36643.1 - 4.2e-23 82.4 0.1 1e-22 81.2 0.1 1.7 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 OAG36643.1 - 3.3e-05 23.9 0.0 6.3e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_7 PF13241.6 OAG36643.1 - 0.0075 16.7 0.1 0.024 15.1 0.0 1.9 2 0 0 2 2 2 1 Putative NAD(P)-binding NAD_binding_2 PF03446.15 OAG36643.1 - 0.043 14.0 0.3 0.19 11.9 0.0 2.1 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Gp_dh_N PF00044.24 OAG36643.1 - 0.064 13.6 0.0 0.2 12.0 0.0 1.9 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Aldo_ket_red PF00248.21 OAG36644.1 - 1.1e-43 149.6 0.0 7.6e-42 143.5 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family MIOX PF05153.15 OAG36645.1 - 1.5e-126 421.1 1.4 1.9e-126 420.7 1.4 1.1 1 0 0 1 1 1 1 Myo-inositol oxygenase HD PF01966.22 OAG36645.1 - 0.058 13.6 0.1 1.4 9.2 0.0 2.4 2 0 0 2 2 2 0 HD domain Sugar_tr PF00083.24 OAG36647.1 - 1.3e-61 208.9 6.6 1.5e-61 208.7 6.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG36647.1 - 4.3e-14 52.2 9.0 6e-14 51.7 9.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Phage_holin_3_2 PF04550.12 OAG36647.1 - 0.04 14.5 2.3 0.045 14.3 0.8 1.8 2 0 0 2 2 2 0 Phage holin family 2 MFS_4 PF06779.14 OAG36647.1 - 0.3 10.3 12.5 0.25 10.6 9.2 2.2 2 1 0 2 2 2 0 Uncharacterised MFS-type transporter YbfB TPR_1 PF00515.28 OAG36649.1 - 0.00028 20.6 0.4 0.037 13.9 0.1 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 OAG36649.1 - 0.042 14.0 0.2 0.73 10.1 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Abhydrolase_3 PF07859.13 OAG36650.1 - 2.2e-05 24.4 0.0 3.2e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold MAP65_ASE1 PF03999.12 OAG36651.1 - 7 5.2 15.7 9.2 4.8 15.7 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Topo-VIb_trans PF09239.11 OAG36652.1 - 0.17 11.7 0.0 0.3 10.9 0.0 1.4 1 1 1 2 2 2 0 Topoisomerase VI B subunit, transducer S-AdoMet_synt_C PF02773.16 OAG36653.1 - 7.5e-23 81.0 1.8 2e-14 53.8 1.5 2.0 1 1 1 2 2 2 2 S-adenosylmethionine synthetase, C-terminal domain Thump_like PF18096.1 OAG36653.1 - 0.13 12.3 0.0 2.1 8.4 0.0 2.1 2 0 0 2 2 2 0 THUMP domain-like Aldedh PF00171.22 OAG36655.1 - 1.2e-19 70.2 0.1 1.4e-19 70.0 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family adh_short PF00106.25 OAG36657.1 - 0.12 11.8 0.0 0.14 11.6 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase TSC22 PF01166.18 OAG36658.1 - 0.047 14.0 0.2 0.1 12.9 0.2 1.6 1 1 0 1 1 1 0 TSC-22/dip/bun family Vfa1 PF08432.10 OAG36659.1 - 0.052 13.9 7.3 0.11 12.8 7.3 1.5 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Myosin_N PF02736.19 OAG36662.1 - 0.14 12.0 0.3 0.27 11.1 0.3 1.5 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain DUF3357 PF11837.8 OAG36664.1 - 0.16 12.4 0.0 0.36 11.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) F-box_4 PF15966.5 OAG36668.1 - 0.00021 21.1 0.0 0.0019 18.1 0.0 2.4 2 0 0 2 2 2 1 F-box F-box PF00646.33 OAG36668.1 - 0.015 15.2 0.0 0.033 14.1 0.0 1.6 1 0 0 1 1 1 0 F-box domain Metal_resist PF13801.6 OAG36670.1 - 0.03 14.5 3.8 1.1 9.5 0.2 2.6 2 1 1 3 3 3 0 Heavy-metal resistance Zn_clus PF00172.18 OAG36672.1 - 0.56 10.4 3.9 0.74 10.0 1.1 2.2 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain NDT80_PhoG PF05224.12 OAG36673.1 - 3.3e-16 60.1 0.0 4.3e-16 59.7 0.0 1.2 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family MFS_1 PF07690.16 OAG36674.1 - 1.1e-07 31.1 0.3 1.1e-07 31.1 0.3 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Elf1 PF05129.13 OAG36676.1 - 3.5e-15 55.8 3.2 6.8e-15 54.9 3.2 1.4 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like DUF917 PF06032.12 OAG36676.1 - 1.5e-12 47.0 0.1 2.4e-12 46.3 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF917) DUF1635 PF07795.11 OAG36678.1 - 0.0089 15.9 1.0 0.012 15.5 1.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1635) DUF1682 PF07946.14 OAG36678.1 - 0.044 13.0 0.7 0.048 12.9 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) SLX9 PF15341.6 OAG36678.1 - 0.054 13.9 2.7 0.076 13.4 2.7 1.2 1 0 0 1 1 1 0 Ribosome biogenesis protein SLX9 Fmp27_WPPW PF10359.9 OAG36678.1 - 0.12 11.2 1.3 0.15 10.9 1.3 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DDE_1 PF03184.19 OAG36679.1 - 1.9e-05 24.4 0.1 0.0001 22.0 0.1 2.0 2 0 0 2 2 2 1 DDE superfamily endonuclease Fungal_trans PF04082.18 OAG36680.1 - 2.9e-24 85.5 0.0 5.2e-24 84.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Tyrosinase PF00264.20 OAG36680.1 - 0.15 12.4 0.8 0.34 11.2 0.3 1.7 1 1 1 2 2 2 0 Common central domain of tyrosinase adh_short_C2 PF13561.6 OAG36681.1 - 4e-52 177.1 2.8 3.9e-29 101.9 0.0 3.0 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG36681.1 - 2.2e-36 125.2 2.2 7.3e-35 120.2 2.2 2.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG36681.1 - 1.2e-08 35.1 0.1 2.1e-08 34.3 0.1 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG36681.1 - 0.00033 20.2 0.2 0.00081 18.9 0.3 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 OAG36681.1 - 0.0027 18.0 0.6 0.0047 17.2 0.6 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain 3HCDH_N PF02737.18 OAG36681.1 - 0.003 17.5 0.3 0.0042 17.0 0.3 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HHH_5 PF14520.6 OAG36681.1 - 0.081 13.5 0.3 0.19 12.4 0.3 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix domain PDZ_3 PF17815.1 OAG36681.1 - 0.18 11.7 0.0 0.3 10.9 0.0 1.3 1 0 0 1 1 1 0 PDZ domain TRI12 PF06609.13 OAG36682.1 - 1e-46 159.6 25.0 1.2e-46 159.4 25.0 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG36682.1 - 4.8e-20 71.8 47.7 4.8e-20 71.8 47.7 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG36682.1 - 2.2e-10 40.0 8.4 2.2e-10 40.0 8.4 2.8 2 1 1 3 3 3 1 Sugar (and other) transporter Lactamase_B PF00753.27 OAG36683.1 - 1.4e-10 41.5 0.8 3.1e-10 40.4 0.8 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OAG36683.1 - 0.00021 20.9 0.0 0.00045 19.8 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Fungal_trans PF04082.18 OAG36684.1 - 1.5e-07 30.7 0.2 2.9e-07 29.8 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 OAG36684.1 - 4.2e-05 23.8 10.2 0.18 12.3 3.4 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAG36684.1 - 0.00018 22.1 8.5 0.29 12.1 3.2 3.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.12 OAG36684.1 - 0.0049 17.1 2.6 0.0097 16.2 2.6 1.5 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding Zn-ribbon_8 PF09723.10 OAG36684.1 - 0.12 12.5 2.5 0.33 11.1 2.5 1.8 1 0 0 1 1 1 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 OAG36684.1 - 0.42 11.1 11.0 13 6.4 2.7 3.5 3 0 0 3 3 3 0 Zinc-finger double domain Zn_Tnp_IS1595 PF12760.7 OAG36684.1 - 9.4 6.3 11.0 0.26 11.3 1.3 3.0 3 0 0 3 3 3 0 Transposase zinc-ribbon domain adh_short_C2 PF13561.6 OAG36685.1 - 3.3e-57 193.8 0.0 4e-57 193.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG36685.1 - 4.8e-44 150.2 0.0 5.7e-44 149.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG36685.1 - 0.0062 16.5 0.1 0.012 15.5 0.1 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG36685.1 - 0.032 13.7 0.0 0.058 12.9 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family AdoHcyase_NAD PF00670.21 OAG36685.1 - 0.032 14.3 0.2 0.06 13.4 0.2 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain TrkA_N PF02254.18 OAG36685.1 - 0.037 14.3 0.0 0.077 13.3 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Sacchrp_dh_NADP PF03435.18 OAG36685.1 - 0.14 12.5 0.0 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Sugar_tr PF00083.24 OAG36686.1 - 3.4e-82 276.7 21.0 4e-82 276.5 21.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG36686.1 - 8.6e-21 74.2 34.8 4.1e-16 58.8 24.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4387 PF14330.6 OAG36687.1 - 2.9e-33 114.5 0.0 5.2e-33 113.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4387) AtuA PF07287.11 OAG36687.1 - 1.8e-19 69.7 0.0 1.1e-18 67.1 0.0 1.9 1 1 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA Aldedh PF00171.22 OAG36688.1 - 7.1e-141 469.9 0.5 8.4e-141 469.6 0.5 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family PEP_mutase PF13714.6 OAG36689.1 - 4.7e-45 153.9 2.5 5.5e-45 153.7 2.5 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 OAG36689.1 - 1.2e-18 66.9 0.2 1.9e-18 66.3 0.2 1.2 1 0 0 1 1 1 1 Isocitrate lyase family MR_MLE_C PF13378.6 OAG36689.1 - 0.074 12.6 0.6 0.2 11.2 0.1 2.0 2 1 0 2 2 2 0 Enolase C-terminal domain-like tRNA_SAD PF07973.14 OAG36691.1 - 0.091 12.9 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 Threonyl and Alanyl tRNA synthetase second additional domain F-box PF00646.33 OAG36692.1 - 0.012 15.4 0.0 0.03 14.2 0.0 1.6 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 OAG36692.1 - 0.088 12.7 0.1 0.18 11.7 0.1 1.5 1 0 0 1 1 1 0 F-box-like ADH_zinc_N PF00107.26 OAG36693.1 - 7.8e-09 35.6 0.1 1.2e-08 35.0 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG36693.1 - 0.0002 21.2 0.0 0.00047 20.0 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Pectate_lyase_3 PF12708.7 OAG36694.1 - 3e-96 321.4 21.5 1.9e-83 279.5 6.0 3.2 3 1 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 OAG36694.1 - 3.7e-08 32.9 3.3 0.0023 17.6 0.1 2.8 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Aminotran_1_2 PF00155.21 OAG36695.1 - 1.7e-20 73.5 0.0 2e-20 73.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 OAG36695.1 - 0.00036 19.4 0.0 0.00097 18.0 0.0 1.6 2 0 0 2 2 2 1 Alanine-glyoxylate amino-transferase AMP-binding PF00501.28 OAG36697.1 - 2.5e-54 184.5 0.0 3e-54 184.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG36697.1 - 7.9e-12 46.0 0.7 2.1e-11 44.7 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain CDC24 PF06395.11 OAG36697.1 - 0.072 13.4 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 CDC24 Calponin NMO PF03060.15 OAG36697.1 - 0.078 12.4 0.2 0.12 11.8 0.2 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase PARP PF00644.20 OAG36699.1 - 5.8e-31 107.6 0.0 8.3e-31 107.1 0.0 1.2 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain WGR PF05406.15 OAG36699.1 - 3.1e-07 30.4 0.2 6.3e-07 29.4 0.2 1.5 1 0 0 1 1 1 1 WGR domain PARP_reg PF02877.14 OAG36699.1 - 0.0063 16.6 0.0 0.011 15.8 0.0 1.4 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain ADH_zinc_N PF00107.26 OAG36700.1 - 7.5e-10 38.9 0.3 1.2e-09 38.3 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG36700.1 - 4e-08 33.1 0.0 1.2e-07 31.6 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 OAG36700.1 - 0.015 16.3 0.2 0.027 15.5 0.2 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase FAD_binding_3 PF01494.19 OAG36701.1 - 1e-66 225.6 0.0 1.3e-66 225.2 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 OAG36701.1 - 0.0036 16.6 0.1 0.17 11.1 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAG36701.1 - 0.0044 16.3 0.0 0.022 14.0 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG36701.1 - 0.051 13.8 0.0 0.16 12.2 0.0 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAG36701.1 - 0.066 12.8 0.1 1.2 8.7 0.0 2.1 1 1 0 2 2 2 0 FAD dependent oxidoreductase RVT_3 PF13456.6 OAG36701.1 - 0.1 12.4 0.1 1 9.2 0.1 2.2 2 0 0 2 2 2 0 Reverse transcriptase-like Thi4 PF01946.17 OAG36701.1 - 0.15 11.3 0.0 0.5 9.6 0.0 1.8 2 0 0 2 2 2 0 Thi4 family HI0933_like PF03486.14 OAG36701.1 - 0.15 10.7 0.0 0.51 9.0 0.0 1.7 2 0 0 2 2 2 0 HI0933-like protein Cupin_8 PF13621.6 OAG36702.1 - 3.8e-49 167.7 0.0 6.5e-49 166.9 0.0 1.5 1 1 0 1 1 1 1 Cupin-like domain Cupin_3 PF05899.12 OAG36702.1 - 0.14 11.8 0.0 11 5.7 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF861) JmjC PF02373.22 OAG36702.1 - 0.16 12.4 0.1 1.6 9.2 0.0 2.4 3 0 0 3 3 3 0 JmjC domain, hydroxylase HAD_2 PF13419.6 OAG36703.1 - 2.5e-24 86.3 0.0 3.9e-24 85.7 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OAG36703.1 - 7.9e-13 49.2 0.0 7.6e-12 46.0 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OAG36703.1 - 7.3e-07 29.2 0.0 1.5e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 OAG36703.1 - 0.00012 22.6 0.0 0.00016 22.2 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 OAG36703.1 - 0.045 13.9 0.0 0.13 12.3 0.0 1.7 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase SAP18 PF06487.12 OAG36704.1 - 4.8e-45 153.2 0.0 5.9e-45 152.9 0.0 1.1 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) Cir_Bir_Yir PF06022.11 OAG36705.1 - 0.09 12.3 0.1 0.6 9.5 0.0 2.0 2 0 0 2 2 2 0 Plasmodium variant antigen protein Cir/Yir/Bir Lactonase PF10282.9 OAG36706.1 - 1.2e-25 90.6 0.1 3.3e-25 89.1 0.1 1.7 1 1 0 1 1 1 1 Lactonase, 7-bladed beta-propeller SGL PF08450.12 OAG36706.1 - 0.00022 20.9 0.0 0.001 18.7 0.0 2.1 2 0 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region Ank_4 PF13637.6 OAG36707.1 - 4e-05 24.1 0.0 0.16 12.6 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG36707.1 - 6.2e-05 23.1 0.0 0.49 11.1 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 OAG36707.1 - 0.0003 21.3 0.0 0.00053 20.5 0.0 1.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) ALF PF03752.13 OAG36707.1 - 0.016 15.2 0.0 0.031 14.3 0.0 1.5 1 0 0 1 1 1 0 Short repeats of unknown function Ank PF00023.30 OAG36707.1 - 0.12 12.9 0.0 2.2 8.9 0.0 2.2 1 1 1 2 2 2 0 Ankyrin repeat CAP_N PF01213.19 OAG36707.1 - 0.22 10.9 0.1 0.32 10.4 0.1 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Nitroreductase PF00881.24 OAG36708.1 - 2.6e-16 60.2 0.0 2.9e-16 60.0 0.0 1.0 1 0 0 1 1 1 1 Nitroreductase family MFS_1 PF07690.16 OAG36709.1 - 5e-43 147.4 43.7 1.2e-41 142.9 41.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG36709.1 - 2.5e-10 39.8 9.5 2.5e-10 39.8 9.5 2.1 2 1 0 2 2 2 1 Sugar (and other) transporter Tcp11 PF05794.13 OAG36709.1 - 0.44 9.6 1.5 0.63 9.1 1.5 1.1 1 0 0 1 1 1 0 T-complex protein 11 WW PF00397.26 OAG36711.1 - 2.4e-08 33.9 1.7 7.3e-08 32.4 1.7 1.9 1 0 0 1 1 1 1 WW domain Gly-zipper_YMGG PF13441.6 OAG36711.1 - 0.026 14.3 1.4 0.045 13.5 1.4 1.3 1 0 0 1 1 1 0 YMGG-like Gly-zipper TipAS PF07739.13 OAG36711.1 - 0.38 11.3 2.6 0.66 10.5 2.3 1.5 1 1 0 1 1 1 0 TipAS antibiotic-recognition domain YtxH PF12732.7 OAG36711.1 - 0.76 10.4 3.1 3 8.4 3.1 2.1 1 1 0 1 1 1 0 YtxH-like protein TFIIF_alpha PF05793.12 OAG36712.1 - 0.18 10.3 6.0 0.28 9.7 6.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDC45 PF02724.14 OAG36712.1 - 0.86 7.8 7.4 1.3 7.3 7.4 1.1 1 0 0 1 1 1 0 CDC45-like protein PPP4R2 PF09184.11 OAG36712.1 - 4.1 6.9 8.6 7 6.2 8.6 1.3 1 0 0 1 1 1 0 PPP4R2 Sugar_tr PF00083.24 OAG36713.1 - 1.1e-71 242.1 31.5 1.3e-71 241.8 31.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG36713.1 - 4.4e-28 98.2 47.6 2.6e-25 89.1 29.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2070 PF09843.9 OAG36713.1 - 4.3 5.5 14.6 7.9 4.6 14.6 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF3618 PF12277.8 OAG36713.1 - 5.9 7.2 4.9 5 7.5 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3618) GST_N_3 PF13417.6 OAG36714.1 - 6.1e-13 49.0 0.0 1.2e-12 48.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OAG36714.1 - 4.7e-07 30.0 0.1 1.2e-06 28.7 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAG36714.1 - 0.00016 21.6 0.0 0.0004 20.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 OAG36714.1 - 0.03 15.1 0.0 0.19 12.5 0.0 2.1 1 1 0 1 1 1 0 Glutathione S-transferase N-terminal domain GST_C PF00043.25 OAG36714.1 - 0.031 14.5 0.1 0.12 12.6 0.1 1.9 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 OAG36714.1 - 0.044 14.1 0.2 0.12 12.7 0.0 1.8 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain MRJP PF03022.16 OAG36715.1 - 6e-20 71.8 0.0 7.2e-20 71.5 0.0 1.1 1 0 0 1 1 1 1 Major royal jelly protein NHL PF01436.21 OAG36715.1 - 0.0021 18.0 0.5 1.7 8.8 0.0 4.2 5 0 0 5 5 5 2 NHL repeat DUF2347 PF09804.9 OAG36716.1 - 1.3e-81 274.3 0.0 1.5e-80 270.8 0.0 2.1 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.6 OAG36716.1 - 3.4e-45 154.7 6.1 3.1e-31 109.1 0.5 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF4484) Avl9 PF09794.9 OAG36716.1 - 0.00035 19.4 0.0 0.054 12.2 0.1 3.0 3 0 0 3 3 3 2 Transport protein Avl9 Abhydrolase_6 PF12697.7 OAG36718.1 - 6.2e-14 53.1 2.5 6.2e-14 53.1 2.5 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG36718.1 - 1.2e-11 44.3 0.0 2e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OAG36718.1 - 9e-07 28.8 0.1 1.4e-06 28.1 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 OAG36718.1 - 3.3e-06 27.1 0.0 5.1e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OAG36718.1 - 0.0017 17.9 0.0 0.083 12.4 0.0 2.5 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 OAG36718.1 - 0.01 15.6 0.0 0.5 10.1 0.0 2.5 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Say1_Mug180 PF10340.9 OAG36718.1 - 0.06 12.2 0.0 0.088 11.6 0.0 1.1 1 0 0 1 1 1 0 Steryl acetyl hydrolase ADH_N PF08240.12 OAG36719.1 - 1.4e-24 86.0 1.6 1.4e-24 86.0 1.6 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG36719.1 - 2.2e-07 30.9 0.0 9.7e-07 28.8 0.0 2.0 1 1 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 OAG36719.1 - 0.00027 20.3 0.0 0.00046 19.5 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 OAG36719.1 - 0.0023 17.3 0.0 0.0076 15.6 0.1 1.7 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PAN_2 PF08276.11 OAG36720.1 - 0.13 12.4 0.4 0.13 12.4 0.4 2.8 2 1 0 2 2 2 0 PAN-like domain PAN_4 PF14295.6 OAG36720.1 - 0.17 11.8 7.6 0.68 9.9 7.1 2.4 1 1 0 1 1 1 0 PAN domain SOG2 PF10428.9 OAG36720.1 - 0.99 8.5 24.1 1.2 8.3 24.1 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein GCHY-1 PF02649.14 OAG36720.1 - 7 6.1 6.5 10 5.5 6.5 1.2 1 0 0 1 1 1 0 Type I GTP cyclohydrolase folE2 SNF2_N PF00176.23 OAG36721.1 - 3.1e-59 200.5 0.0 4.7e-59 199.9 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OAG36721.1 - 8.8e-14 51.8 0.0 1.9e-13 50.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG36721.1 - 9.5e-12 45.2 0.0 2e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SSURE PF11966.8 OAG36721.1 - 0.087 12.6 0.0 0.27 11.0 0.0 1.9 1 0 0 1 1 1 0 Fibronectin-binding repeat DUF2075 PF09848.9 OAG36721.1 - 0.11 11.7 0.0 0.21 10.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) TolA_bind_tri PF16331.5 OAG36724.1 - 0.24 11.5 1.1 0.43 10.7 1.1 1.4 1 0 0 1 1 1 0 TolA binding protein trimerisation FAD_binding_3 PF01494.19 OAG36725.1 - 7e-09 35.4 2.1 7.4e-05 22.1 0.0 2.7 3 0 0 3 3 3 2 FAD binding domain NAD_binding_9 PF13454.6 OAG36725.1 - 7.7e-06 26.0 1.0 0.074 13.0 0.6 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding SE PF08491.10 OAG36725.1 - 0.0007 18.7 0.0 0.013 14.6 0.0 2.0 2 0 0 2 2 2 1 Squalene epoxidase Pyr_redox_2 PF07992.14 OAG36725.1 - 0.013 14.7 0.3 2.8 7.1 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 OAG36725.1 - 0.054 12.8 0.0 0.076 12.3 0.0 1.2 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase MIF PF01187.18 OAG36726.1 - 9.9e-11 41.9 0.0 1.5e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Macro PF01661.21 OAG36727.1 - 1.4e-10 41.2 0.0 1.7e-06 28.0 0.0 2.3 2 0 0 2 2 2 2 Macro domain DnaJ PF00226.31 OAG36727.1 - 0.0039 17.3 0.1 0.0081 16.3 0.1 1.6 1 0 0 1 1 1 1 DnaJ domain TRI12 PF06609.13 OAG36728.1 - 3.8e-42 144.5 24.0 4.8e-42 144.2 24.0 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG36728.1 - 4.7e-17 61.9 46.3 4.7e-17 61.9 46.3 3.0 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG36728.1 - 4.6e-11 42.2 6.5 4.6e-11 42.2 6.5 3.7 4 1 1 5 5 5 1 Sugar (and other) transporter Neurensin PF14927.6 OAG36728.1 - 0.81 9.4 0.0 0.81 9.4 0.0 3.3 3 1 1 4 4 4 0 Neurensin adh_short PF00106.25 OAG36729.1 - 7.2e-35 120.2 0.0 8.8e-35 119.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG36729.1 - 5.3e-24 85.1 0.0 6.9e-24 84.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG36729.1 - 3e-06 27.3 0.0 1e-05 25.5 0.0 1.8 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 OAG36729.1 - 6.8e-05 22.4 0.0 0.00011 21.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Wax2_C PF12076.8 OAG36729.1 - 0.024 14.4 0.0 0.034 13.9 0.0 1.2 1 0 0 1 1 1 0 WAX2 C-terminal domain Zea_mays_MuDR PF05928.11 OAG36729.1 - 0.15 11.7 0.3 0.5 10.0 0.4 1.7 2 0 0 2 2 2 0 Zea mays MURB-like protein (MuDR) adh_short_C2 PF13561.6 OAG36730.1 - 8.4e-69 231.7 1.5 1e-68 231.4 1.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG36730.1 - 8.9e-50 168.9 1.2 1.1e-49 168.5 1.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG36730.1 - 1.2e-11 44.9 2.1 1.8e-11 44.3 2.1 1.2 1 0 0 1 1 1 1 KR domain Methyltransf_25 PF13649.6 OAG36730.1 - 0.016 15.9 0.2 0.04 14.6 0.2 1.8 1 1 0 1 1 1 0 Methyltransferase domain Epimerase PF01370.21 OAG36730.1 - 0.032 13.7 0.8 0.16 11.4 0.8 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Ubie_methyltran PF01209.18 OAG36730.1 - 0.054 12.8 0.6 0.087 12.1 0.1 1.6 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Ldh_1_N PF00056.23 OAG36730.1 - 0.075 13.1 0.4 0.15 12.1 0.4 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain NmrA PF05368.13 OAG36731.1 - 5.2e-26 91.6 0.0 6e-26 91.4 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG36731.1 - 1.4e-10 41.4 0.0 2e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 OAG36731.1 - 0.00033 20.9 0.1 0.0015 18.8 0.0 1.9 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 OAG36731.1 - 0.019 15.4 0.0 0.039 14.4 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 OAG36731.1 - 0.02 15.0 0.0 0.033 14.3 0.0 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus 3Beta_HSD PF01073.19 OAG36732.1 - 4.3e-07 29.2 0.0 7.7e-07 28.4 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 OAG36732.1 - 2.1e-06 27.4 0.0 3.3e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 OAG36732.1 - 2.5e-05 24.2 1.3 0.014 15.3 1.4 3.1 2 1 0 2 2 2 1 NAD(P)H-binding adh_short PF00106.25 OAG36732.1 - 0.00055 19.4 0.4 0.029 13.8 0.2 2.8 2 1 0 2 2 2 1 short chain dehydrogenase GDP_Man_Dehyd PF16363.5 OAG36732.1 - 0.0044 16.4 0.0 0.0069 15.8 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase KR PF08659.10 OAG36732.1 - 0.024 14.5 0.7 0.06 13.2 0.7 1.6 1 1 0 1 1 1 0 KR domain NmrA PF05368.13 OAG36732.1 - 0.029 13.9 0.2 0.047 13.2 0.2 1.4 1 0 0 1 1 1 0 NmrA-like family PRAI PF00697.22 OAG36732.1 - 0.15 11.8 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase Abhydrolase_3 PF07859.13 OAG36733.1 - 9.9e-26 90.9 0.0 1.3e-25 90.5 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 OAG36733.1 - 2.9e-14 52.7 0.0 3.7e-14 52.4 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Pyr_redox_3 PF13738.6 OAG36734.1 - 2.4e-16 59.9 0.0 3.9e-15 55.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAG36734.1 - 6e-13 48.7 0.0 1.6e-10 40.7 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 OAG36734.1 - 1.4e-11 43.5 0.0 2.6e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OAG36734.1 - 1.2e-07 31.8 0.0 6.3e-07 29.5 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 OAG36734.1 - 0.0024 17.2 0.0 1.3 8.2 0.1 2.4 2 0 0 2 2 2 2 FAD binding domain NAD_binding_9 PF13454.6 OAG36734.1 - 0.0078 16.2 0.1 7.6 6.5 0.1 4.1 5 0 0 5 5 5 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 OAG36734.1 - 0.0098 16.4 0.6 11 6.7 0.0 2.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 OAG36734.1 - 0.017 14.5 0.0 0.036 13.4 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 OAG36734.1 - 0.018 14.1 0.2 0.053 12.6 0.1 1.8 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.14 OAG36734.1 - 0.033 12.9 0.3 7.8 5.1 0.4 2.5 2 0 0 2 2 2 0 HI0933-like protein Shikimate_DH PF01488.20 OAG36734.1 - 0.046 13.8 0.1 0.13 12.3 0.0 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DUF501 PF04417.12 OAG36734.1 - 0.076 12.8 0.0 0.24 11.2 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF501) DAO PF01266.24 OAG36734.1 - 0.089 12.4 0.0 2.2 7.8 0.0 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.22 OAG36734.1 - 0.11 11.5 0.3 8.9 5.3 0.0 3.0 3 0 0 3 3 3 0 Glucose inhibited division protein A AIRC PF00731.20 OAG36734.1 - 0.19 11.3 0.0 0.6 9.7 0.0 1.8 2 0 0 2 2 2 0 AIR carboxylase Pfg27 PF09216.10 OAG36734.1 - 0.24 11.2 2.1 0.53 10.1 0.2 2.4 2 1 0 2 2 2 0 Pfg27 TRI12 PF06609.13 OAG36735.1 - 1.7e-41 142.3 25.4 1.7e-41 142.3 25.4 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG36735.1 - 2.6e-18 66.1 48.7 2.6e-18 66.1 48.7 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG36735.1 - 2.9e-11 42.9 8.9 2.9e-11 42.9 8.9 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter Fungal_trans PF04082.18 OAG36736.1 - 1.4e-17 63.6 0.0 2.7e-17 62.7 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG36736.1 - 4.6e-06 26.7 7.9 8.5e-06 25.8 7.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ABC_tran_CTD PF16326.5 OAG36736.1 - 0.089 13.1 1.1 0.21 11.9 0.1 2.2 2 0 0 2 2 2 0 ABC transporter C-terminal domain Uds1 PF15456.6 OAG36736.1 - 0.14 12.3 4.7 9.5 6.4 0.0 2.8 2 1 0 2 2 2 0 Up-regulated During Septation AIP3 PF03915.13 OAG36737.1 - 6.1e-148 493.3 14.0 6.1e-148 493.3 14.0 2.2 3 0 0 3 3 3 1 Actin interacting protein 3 Med9 PF07544.13 OAG36737.1 - 0.22 11.6 9.6 13 6.0 0.0 5.2 4 1 1 5 5 5 0 RNA polymerase II transcription mediator complex subunit 9 Lectin_N PF03954.14 OAG36737.1 - 0.27 11.0 2.9 0.2 11.4 0.2 2.2 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain Syntaxin_2 PF14523.6 OAG36737.1 - 0.29 11.5 0.1 0.29 11.5 0.1 4.4 3 2 0 3 3 3 0 Syntaxin-like protein Med11 PF10280.9 OAG36737.1 - 0.89 10.0 6.7 1.3 9.5 0.0 3.7 3 1 0 3 3 3 0 Mediator complex protein Nop52 PF05997.12 OAG36738.1 - 2.9e-35 122.0 0.1 3.7e-35 121.7 0.1 1.1 1 0 0 1 1 1 1 Nucleolar protein,Nop52 ArgoL1 PF08699.10 OAG36738.1 - 0.1 12.3 0.0 1 9.1 0.0 2.2 2 0 0 2 2 2 0 Argonaute linker 1 domain PAS_9 PF13426.7 OAG36739.1 - 3.1e-16 59.5 0.2 8.4e-16 58.1 0.0 1.9 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 OAG36739.1 - 0.0092 16.0 0.0 0.026 14.5 0.0 1.8 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 OAG36739.1 - 0.013 15.7 0.0 0.087 13.1 0.0 2.3 3 0 0 3 3 3 0 PAS fold DUF1295 PF06966.12 OAG36740.1 - 1.3e-38 132.9 7.2 1.7e-38 132.5 7.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.14 OAG36740.1 - 0.00076 19.9 1.7 0.58 10.6 0.0 3.2 3 0 0 3 3 3 2 Isoprenylcysteine carboxyl methyltransferase (ICMT) family DUF2517 PF10725.9 OAG36740.1 - 0.069 12.9 0.1 0.34 10.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2517) Topoisom_bac PF01131.20 OAG36741.1 - 1.7e-106 356.7 0.0 2.1e-106 356.4 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 OAG36741.1 - 4e-14 52.7 0.0 1.7e-13 50.7 0.0 2.0 3 0 0 3 3 3 1 Toprim domain ATP-synt_C PF00137.21 OAG36742.1 - 0.31 11.4 2.7 0.71 10.3 2.7 1.6 1 0 0 1 1 1 0 ATP synthase subunit C DUF2985 PF11204.8 OAG36743.1 - 7.7e-36 122.1 1.0 7.7e-36 122.1 1.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2985) Phage_holin_3_6 PF07332.11 OAG36743.1 - 3.2 7.8 4.8 11 6.0 0.1 2.3 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Sen15 PF09631.10 OAG36744.1 - 1.4e-12 47.8 0.0 1.5e-08 34.8 0.0 3.1 2 1 0 2 2 2 2 Sen15 protein UBD PF16455.5 OAG36745.1 - 5e-37 126.3 0.0 7.9e-37 125.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-binding domain ubiquitin PF00240.23 OAG36745.1 - 9.7e-05 22.0 0.0 0.00017 21.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 OAG36745.1 - 0.018 14.9 0.0 0.032 14.1 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 OAG36745.1 - 0.025 14.9 0.0 0.054 13.9 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-like domain DUF2407 PF10302.9 OAG36745.1 - 0.074 13.6 0.2 0.24 12.0 0.1 1.9 1 1 1 2 2 2 0 DUF2407 ubiquitin-like domain Vac_ImportDeg PF09783.9 OAG36746.1 - 2.5e-57 193.2 0.8 3.2e-57 192.8 0.8 1.1 1 0 0 1 1 1 1 Vacuolar import and degradation protein Mago_nashi PF02792.14 OAG36747.1 - 3.9e-72 241.0 0.1 4.4e-72 240.8 0.1 1.0 1 0 0 1 1 1 1 Mago nashi protein APH PF01636.23 OAG36748.1 - 0.00012 22.0 0.0 0.00015 21.8 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 OAG36748.1 - 0.0052 16.4 0.3 0.0076 15.9 0.3 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase NMT1 PF09084.11 OAG36749.1 - 2.5e-05 24.3 0.0 0.00059 19.8 0.0 2.2 2 0 0 2 2 2 1 NMT1/THI5 like VitK2_biosynth PF02621.14 OAG36749.1 - 7.7e-05 22.3 0.0 0.016 14.7 0.0 2.2 2 0 0 2 2 2 2 Menaquinone biosynthesis SBP_bac_3 PF00497.20 OAG36749.1 - 0.0015 18.0 0.0 0.0038 16.7 0.0 1.6 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Phosphonate-bd PF12974.7 OAG36749.1 - 0.0041 16.8 0.0 0.0062 16.2 0.0 1.3 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein SHS2_FTSA PF02491.20 OAG36749.1 - 0.16 12.4 0.0 0.31 11.5 0.0 1.5 1 0 0 1 1 1 0 SHS2 domain inserted in FTSA MFS_1 PF07690.16 OAG36750.1 - 1.6e-39 135.8 24.7 1.6e-39 135.8 24.7 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 OAG36750.1 - 8e-07 27.8 3.1 1.3e-06 27.1 3.1 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 OAG36750.1 - 0.091 11.0 22.7 0.075 11.3 10.2 3.5 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family FAD_binding_3 PF01494.19 OAG36751.1 - 4.2e-21 75.6 0.0 6.2e-21 75.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAG36751.1 - 9.8e-09 35.2 2.3 0.00042 20.0 0.6 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.14 OAG36751.1 - 0.0013 17.5 1.6 0.0028 16.4 1.6 1.5 1 1 0 1 1 1 1 HI0933-like protein SE PF08491.10 OAG36751.1 - 0.0051 15.9 0.0 0.021 13.9 0.0 1.9 1 1 0 1 1 1 1 Squalene epoxidase NAD_binding_9 PF13454.6 OAG36751.1 - 0.017 15.1 0.5 1.1 9.3 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 OAG36751.1 - 0.024 14.9 0.8 0.081 13.2 0.0 2.2 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 OAG36751.1 - 0.024 13.7 0.5 0.12 11.4 0.1 2.0 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_2 PF07992.14 OAG36751.1 - 0.057 12.6 6.4 1.7 7.8 6.4 2.3 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG36751.1 - 8.5 5.5 7.0 1.1 8.5 0.2 2.4 1 1 2 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase ketoacyl-synt PF00109.26 OAG36753.1 - 3.3e-75 252.9 0.0 6.2e-75 252.0 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.6 OAG36753.1 - 2.5e-58 197.7 0.0 4.5e-58 196.8 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 OAG36753.1 - 2e-48 164.7 0.0 4.4e-48 163.6 0.0 1.6 1 0 0 1 1 1 1 KR domain Condensation PF00668.20 OAG36753.1 - 2.1e-46 158.6 0.0 4.1e-46 157.6 0.0 1.4 1 0 0 1 1 1 1 Condensation domain Acyl_transf_1 PF00698.21 OAG36753.1 - 3.4e-39 135.2 0.0 1.1e-38 133.5 0.0 1.9 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 OAG36753.1 - 2.2e-32 111.5 0.0 2.7e-31 108.0 0.0 2.5 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 OAG36753.1 - 1.7e-19 70.4 0.0 4.9e-19 68.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAG36753.1 - 5.2e-15 55.7 0.0 7.7e-14 51.9 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 OAG36753.1 - 1.3e-13 51.3 0.0 3.2e-13 50.1 0.0 1.6 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_25 PF13649.6 OAG36753.1 - 1.2e-12 48.4 0.0 5.4e-12 46.3 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG36753.1 - 1.6e-11 44.2 0.0 3.6e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG36753.1 - 3.3e-11 43.7 0.0 1e-10 42.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 OAG36753.1 - 6.3e-08 32.3 0.0 4.7e-07 29.5 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase Ubie_methyltran PF01209.18 OAG36753.1 - 2.2e-06 27.2 0.0 5.4e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family adh_short_C2 PF13561.6 OAG36753.1 - 3.1e-06 26.9 0.1 6.7e-06 25.8 0.1 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Thiolase_N PF00108.23 OAG36753.1 - 4e-06 26.4 0.1 8.6e-06 25.3 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain PP-binding PF00550.25 OAG36753.1 - 0.00031 21.0 1.3 0.00079 19.7 0.3 2.3 2 0 0 2 2 1 1 Phosphopantetheine attachment site Methyltransf_16 PF10294.9 OAG36753.1 - 0.00046 20.0 0.0 0.001 18.8 0.0 1.5 1 0 0 1 1 1 1 Lysine methyltransferase DUF938 PF06080.12 OAG36753.1 - 0.0017 18.2 0.0 0.0043 16.8 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF938) RrnaAD PF00398.20 OAG36753.1 - 0.0018 17.4 0.0 0.004 16.3 0.0 1.5 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase FSH1 PF03959.13 OAG36754.1 - 4.6e-30 104.9 0.0 5.5e-30 104.6 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) ADH_zinc_N PF00107.26 OAG36755.1 - 1.1e-05 25.4 0.0 2.2e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG36755.1 - 1.2e-05 25.2 0.0 2.3e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 OAG36755.1 - 0.066 12.5 0.1 0.18 11.1 0.0 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain p450 PF00067.22 OAG36756.1 - 2.4e-46 158.5 0.0 3e-46 158.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_3 PF01494.19 OAG36757.1 - 8.3e-29 100.9 0.8 1.1e-28 100.5 0.8 1.1 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 OAG36757.1 - 6.9e-08 32.6 0.9 1.7e-07 31.4 0.9 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAG36757.1 - 2e-07 30.5 2.7 1.1e-06 28.1 0.7 2.1 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAG36757.1 - 4.5e-07 29.3 2.1 9.5e-07 28.2 2.1 1.5 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.14 OAG36757.1 - 6e-07 28.7 0.6 0.00058 18.8 0.3 2.3 2 0 0 2 2 2 2 Tryptophan halogenase DAO PF01266.24 OAG36757.1 - 3.7e-06 26.8 5.3 0.00011 21.9 2.6 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.14 OAG36757.1 - 0.00014 20.7 1.6 0.00066 18.5 0.7 2.0 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 OAG36757.1 - 0.00016 21.1 1.6 0.00031 20.2 1.6 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 OAG36757.1 - 0.00017 21.0 0.9 0.00044 19.6 0.5 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OAG36757.1 - 0.00024 20.3 0.4 0.00066 18.9 0.5 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox PF00070.27 OAG36757.1 - 0.00078 20.0 0.4 0.0058 17.2 0.6 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 OAG36757.1 - 0.0044 16.4 1.0 0.016 14.6 0.2 2.0 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.21 OAG36757.1 - 0.0048 16.2 0.2 0.0082 15.5 0.2 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 OAG36757.1 - 0.0061 15.8 0.1 0.018 14.3 0.1 1.7 2 0 0 2 2 2 1 Thi4 family TrkA_N PF02254.18 OAG36757.1 - 0.011 16.0 1.8 0.48 10.7 0.3 2.5 2 0 0 2 2 2 0 TrkA-N domain ApbA PF02558.16 OAG36757.1 - 0.012 15.3 0.2 0.093 12.4 0.2 2.1 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Rossmann-like PF10727.9 OAG36757.1 - 0.089 12.7 0.4 0.24 11.3 0.4 1.8 1 0 0 1 1 1 0 Rossmann-like domain MFS_1 PF07690.16 OAG36758.1 - 3.3e-35 121.6 45.7 3.3e-35 121.6 45.7 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily Aldolase_II PF00596.21 OAG36759.1 - 4.4e-28 98.5 0.1 5.5e-28 98.2 0.1 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Fungal_trans PF04082.18 OAG36760.1 - 3.4e-31 108.3 0.0 5.2e-31 107.7 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain PBCV_basic_adap PF08789.10 OAG36760.1 - 0.0017 18.4 0.0 0.0035 17.4 0.0 1.5 1 0 0 1 1 1 1 PBCV-specific basic adaptor domain Glyco_hydro_85 PF03644.13 OAG36760.1 - 0.015 14.8 0.0 0.025 14.0 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 85 Aldolase_II PF00596.21 OAG36761.1 - 3.6e-29 102.0 0.1 4.4e-29 101.8 0.1 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Adaptin_N PF01602.20 OAG36762.1 - 6.4e-94 315.4 8.4 1e-93 314.7 8.4 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Coatamer_beta_C PF07718.12 OAG36762.1 - 1.8e-59 199.6 0.5 4.5e-59 198.4 0.5 1.7 1 0 0 1 1 1 1 Coatomer beta C-terminal region Coatomer_b_Cpla PF14806.6 OAG36762.1 - 1.1e-55 187.0 1.3 2.2e-55 186.1 0.1 2.2 2 0 0 2 2 2 1 Coatomer beta subunit appendage platform Cnd1 PF12717.7 OAG36762.1 - 1.6e-13 51.0 4.0 2.8e-09 37.2 0.1 3.1 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 OAG36762.1 - 3.2e-09 37.1 12.1 0.00016 22.0 0.0 5.8 3 1 3 6 6 6 3 HEAT repeats Coatomer_g_Cpla PF16381.5 OAG36762.1 - 9e-06 25.8 0.4 5.3e-05 23.3 0.0 2.5 3 0 0 3 3 3 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_EZ PF13513.6 OAG36762.1 - 0.0009 19.7 0.4 0.29 11.7 0.0 4.2 2 1 2 4 4 4 2 HEAT-like repeat HEAT PF02985.22 OAG36762.1 - 0.011 15.9 8.2 0.34 11.3 0.1 5.3 6 0 0 6 6 5 0 HEAT repeat HTH_44 PF14641.6 OAG36762.1 - 0.071 13.5 0.1 0.18 12.2 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix DNA-binding domain of SPT6 HEAT_PBS PF03130.16 OAG36762.1 - 0.092 13.5 0.4 1e+02 4.0 0.0 4.6 5 0 0 5 5 4 0 PBS lyase HEAT-like repeat DUF5578 PF17741.1 OAG36762.1 - 0.11 11.9 4.1 2.8 7.3 0.2 2.8 1 1 1 2 2 2 0 Family of unknown function (DUF5578) Arm PF00514.23 OAG36762.1 - 0.24 11.5 4.6 1.9 8.6 0.1 4.6 6 0 0 6 6 5 0 Armadillo/beta-catenin-like repeat NBD94 PF16830.5 OAG36762.1 - 0.25 11.8 4.4 0.24 11.8 0.9 2.6 2 0 0 2 2 2 0 Nucleotide-Binding Domain 94 of RH AP4E_app_platf PF14807.6 OAG36762.1 - 1.1 9.6 3.6 0.49 10.8 0.3 2.1 2 0 0 2 2 2 0 Adaptin AP4 complex epsilon appendage platform SKI PF01202.22 OAG36764.1 - 8.8e-13 48.7 0.1 1.1e-12 48.3 0.1 1.2 1 0 0 1 1 1 1 Shikimate kinase AAA_33 PF13671.6 OAG36764.1 - 2.8e-12 47.0 0.0 4.1e-12 46.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 OAG36764.1 - 1.1e-08 35.6 0.1 4.6e-08 33.7 0.0 1.9 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.6 OAG36764.1 - 6e-06 26.7 0.1 2.6e-05 24.7 0.0 2.1 1 1 1 2 2 2 1 AAA domain Rad17 PF03215.15 OAG36764.1 - 1.9e-05 24.7 0.0 4.2e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Rad17 P-loop domain Cytidylate_kin PF02224.18 OAG36764.1 - 4e-05 23.5 0.1 7.9e-05 22.5 0.0 1.5 2 0 0 2 2 2 1 Cytidylate kinase AAA_28 PF13521.6 OAG36764.1 - 5.8e-05 23.4 0.1 0.00013 22.2 0.0 1.6 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 OAG36764.1 - 0.00011 22.1 0.0 0.0004 20.3 0.0 1.9 1 1 1 2 2 2 1 NACHT domain AAA PF00004.29 OAG36764.1 - 0.00015 22.2 0.1 0.0003 21.2 0.0 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OAG36764.1 - 0.00017 21.9 0.1 0.00042 20.6 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 OAG36764.1 - 0.00035 20.6 0.0 0.0033 17.5 0.0 2.3 2 1 0 2 2 2 1 AAA domain APS_kinase PF01583.20 OAG36764.1 - 0.00042 20.2 0.0 0.00053 19.9 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase RNA_helicase PF00910.22 OAG36764.1 - 0.00043 20.6 0.0 0.0011 19.4 0.0 1.7 2 0 0 2 2 1 1 RNA helicase AAA_16 PF13191.6 OAG36764.1 - 0.00046 20.6 0.0 0.00051 20.5 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 OAG36764.1 - 0.0016 18.1 0.2 0.01 15.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 OAG36764.1 - 0.0026 17.8 0.0 0.007 16.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Viral_helicase1 PF01443.18 OAG36764.1 - 0.0033 17.2 0.2 0.024 14.4 0.1 2.0 1 1 1 2 2 2 1 Viral (Superfamily 1) RNA helicase Zeta_toxin PF06414.12 OAG36764.1 - 0.0033 16.7 0.0 0.0046 16.3 0.0 1.5 1 1 0 1 1 1 1 Zeta toxin ABC_tran PF00005.27 OAG36764.1 - 0.0042 17.6 0.0 0.0064 17.0 0.0 1.6 1 1 0 1 1 1 1 ABC transporter dNK PF01712.19 OAG36764.1 - 0.0066 16.3 0.2 0.42 10.4 0.0 2.2 1 1 0 2 2 2 1 Deoxynucleoside kinase AAA_19 PF13245.6 OAG36764.1 - 0.0067 16.8 0.8 0.021 15.2 0.8 2.0 1 1 0 1 1 1 1 AAA domain Cytidylate_kin2 PF13189.6 OAG36764.1 - 0.0078 16.4 0.1 0.036 14.2 0.0 2.0 1 1 1 2 2 2 1 Cytidylate kinase-like family RuvB_N PF05496.12 OAG36764.1 - 0.008 15.9 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain DUF2075 PF09848.9 OAG36764.1 - 0.0096 15.2 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) ATPase_2 PF01637.18 OAG36764.1 - 0.01 15.8 0.0 0.031 14.2 0.0 1.7 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_11 PF13086.6 OAG36764.1 - 0.011 15.6 0.4 0.095 12.5 0.4 2.0 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 OAG36764.1 - 0.012 15.6 0.3 0.022 14.7 0.1 1.7 2 1 0 2 2 2 0 NTPase AAA_30 PF13604.6 OAG36764.1 - 0.013 15.2 0.1 0.025 14.3 0.1 1.5 1 1 0 1 1 1 0 AAA domain tRNA_lig_kinase PF08303.11 OAG36764.1 - 0.015 15.4 0.0 0.024 14.7 0.0 1.5 1 1 0 1 1 1 0 tRNA ligase kinase domain CoaE PF01121.20 OAG36764.1 - 0.016 14.9 0.0 0.041 13.6 0.0 1.7 1 1 0 1 1 1 0 Dephospho-CoA kinase PhoH PF02562.16 OAG36764.1 - 0.017 14.6 0.1 0.046 13.2 0.0 1.7 2 0 0 2 2 1 0 PhoH-like protein PRK PF00485.18 OAG36764.1 - 0.023 14.4 0.0 0.043 13.6 0.0 1.6 1 1 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Mg_chelatase PF01078.21 OAG36764.1 - 0.028 13.8 0.0 0.045 13.1 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TsaE PF02367.17 OAG36764.1 - 0.033 14.2 0.1 0.091 12.8 0.0 1.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NB-ARC PF00931.22 OAG36764.1 - 0.034 13.3 0.0 0.11 11.7 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain Thermopsin PF05317.11 OAG36764.1 - 0.035 13.6 0.0 0.072 12.5 0.0 1.5 2 0 0 2 2 2 0 Thermopsin DNA_pol3_delta2 PF13177.6 OAG36764.1 - 0.035 13.9 0.1 0.086 12.6 0.0 1.8 1 1 0 2 2 2 0 DNA polymerase III, delta subunit AAA_23 PF13476.6 OAG36764.1 - 0.05 14.1 0.1 0.26 11.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain ADK PF00406.22 OAG36764.1 - 0.055 13.6 0.7 0.65 10.1 0.7 2.2 1 1 0 1 1 1 0 Adenylate kinase PduV-EutP PF10662.9 OAG36764.1 - 0.077 12.7 0.0 0.22 11.3 0.0 1.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation IPT PF01745.16 OAG36764.1 - 0.091 12.1 0.1 0.22 10.9 0.0 1.7 2 0 0 2 2 2 0 Isopentenyl transferase cobW PF02492.19 OAG36764.1 - 0.13 11.8 0.0 0.37 10.4 0.0 1.8 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ATPase PF06745.13 OAG36764.1 - 0.15 11.4 0.5 0.63 9.3 0.0 2.1 2 1 1 3 3 3 0 KaiC Vps26 PF03643.15 OAG36765.1 - 1.8e-129 430.6 0.5 2e-129 430.4 0.5 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 OAG36765.1 - 0.00013 22.0 0.8 1.2 9.2 0.0 3.4 2 1 2 4 4 4 2 Arrestin (or S-antigen), N-terminal domain DCB PF16213.5 OAG36766.1 - 1.4e-38 132.4 0.1 3.9e-38 130.9 0.1 1.8 1 0 0 1 1 1 1 Dimerisation and cyclophilin-binding domain of Mon2 Sec7_N PF12783.7 OAG36766.1 - 1.8e-21 76.7 0.8 6.5e-21 74.9 0.0 2.5 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Mon2_C PF16206.5 OAG36766.1 - 6e-08 31.3 2.0 3.8e-07 28.7 0.4 2.5 2 0 0 2 2 2 1 C-terminal region of Mon2 protein Dak2 PF02734.17 OAG36766.1 - 0.0027 17.6 0.1 0.0096 15.8 0.1 1.9 1 0 0 1 1 1 1 DAK2 domain DUF1981 PF09324.10 OAG36766.1 - 0.058 13.3 0.0 1.5 8.8 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1981) HEAT PF02985.22 OAG36766.1 - 2 8.9 6.6 1.3 9.5 0.2 4.3 4 0 0 4 4 4 0 HEAT repeat CFEM PF05730.11 OAG36767.1 - 0.00084 19.4 3.5 0.00084 19.4 3.5 2.7 2 1 0 2 2 2 1 CFEM domain UQ_con PF00179.26 OAG36768.1 - 7.5e-16 58.1 0.0 1.3e-15 57.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Sugar_tr PF00083.24 OAG36769.1 - 1.6e-110 370.1 18.4 2e-110 369.8 18.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG36769.1 - 1.2e-28 100.1 35.3 1.4e-28 99.9 21.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily LacY_symp PF01306.19 OAG36769.1 - 5e-05 22.2 6.0 0.00023 20.1 1.2 2.3 2 0 0 2 2 2 2 LacY proton/sugar symporter Halogen_Hydrol PF10112.9 OAG36769.1 - 0.075 13.0 0.9 12 5.8 0.1 2.9 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein MFS_1_like PF12832.7 OAG36769.1 - 3.2 6.5 20.8 3.6 6.3 12.7 3.2 2 1 0 2 2 2 0 MFS_1 like family Fe_hyd_lg_C PF02906.14 OAG36770.1 - 1.3e-54 185.4 0.0 2.4e-54 184.6 0.0 1.4 1 1 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Cid2 PF09774.9 OAG36771.1 - 7.1e-51 172.8 0.0 8.3e-51 172.6 0.0 1.0 1 0 0 1 1 1 1 Caffeine-induced death protein 2 Fapy_DNA_glyco PF01149.24 OAG36772.1 - 2.1e-31 108.9 0.1 7.2e-31 107.2 0.1 2.0 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.14 OAG36772.1 - 2.4e-22 78.7 0.0 4.8e-22 77.7 0.0 1.5 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain FbpA PF05833.11 OAG36772.1 - 0.00059 18.7 0.0 0.0011 17.8 0.0 1.3 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) DTHCT PF08070.11 OAG36772.1 - 0.014 16.1 24.6 0.014 16.1 24.6 2.5 1 1 1 2 2 1 0 DTHCT (NUC029) region Ribosomal_S13 PF00416.22 OAG36772.1 - 0.034 14.5 0.0 0.079 13.4 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein S13/S18 SAPS PF04499.15 OAG36772.1 - 0.31 9.8 9.6 0.43 9.3 9.6 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RXT2_N PF08595.11 OAG36772.1 - 0.98 9.4 11.4 1.9 8.5 11.4 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal LAT PF15234.6 OAG36772.1 - 1.2 8.8 7.7 2.1 8.0 7.7 1.4 1 0 0 1 1 1 0 Linker for activation of T-cells NOA36 PF06524.12 OAG36772.1 - 1.4 8.2 15.1 2.5 7.4 15.1 1.4 1 0 0 1 1 1 0 NOA36 protein DUF913 PF06025.12 OAG36772.1 - 1.4 7.8 5.0 2 7.3 5.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Spore_coat_CotO PF14153.6 OAG36772.1 - 3.4 7.6 19.7 7 6.5 19.7 1.6 1 0 0 1 1 1 0 Spore coat protein CotO Nop14 PF04147.12 OAG36772.1 - 5.2 5.1 27.3 7.4 4.6 27.3 1.1 1 0 0 1 1 1 0 Nop14-like family TFIIF_alpha PF05793.12 OAG36772.1 - 9.9 4.6 37.8 16 3.9 37.8 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) MFS_1 PF07690.16 OAG36773.1 - 3.1e-09 36.2 36.0 3.1e-09 36.2 36.0 2.4 1 1 1 2 2 2 1 Major Facilitator Superfamily FSH1 PF03959.13 OAG36774.1 - 5.7e-68 228.7 0.0 7e-68 228.5 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 OAG36774.1 - 0.0054 17.4 0.3 0.018 15.6 0.3 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG36774.1 - 0.023 14.0 0.1 0.096 11.9 0.0 1.9 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Thioesterase PF00975.20 OAG36774.1 - 0.033 14.3 0.2 0.14 12.3 0.1 1.9 2 0 0 2 2 2 0 Thioesterase domain Abhydrolase_2 PF02230.16 OAG36774.1 - 0.18 11.6 0.3 13 5.5 0.1 2.8 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase KH_6 PF15985.5 OAG36775.1 - 4.1e-18 65.4 0.1 8.3e-18 64.5 0.1 1.5 1 0 0 1 1 1 1 KH domain HSP70 PF00012.20 OAG36776.1 - 9.8e-78 261.8 3.0 2e-77 260.8 1.2 1.9 2 0 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 OAG36776.1 - 3.4e-07 29.4 0.1 5.6e-07 28.7 0.1 1.3 1 0 0 1 1 1 1 MreB/Mbl protein PilM_2 PF11104.8 OAG36776.1 - 1.8e-05 24.0 0.1 0.0037 16.3 0.1 2.3 2 0 0 2 2 2 2 Type IV pilus assembly protein PilM; FAM176 PF14851.6 OAG36776.1 - 0.04 13.6 0.7 0.097 12.3 0.7 1.6 1 0 0 1 1 1 0 FAM176 family DNA_pol_phi PF04931.13 OAG36776.1 - 3.8 5.5 7.3 6.3 4.8 6.0 1.8 2 0 0 2 2 2 0 DNA polymerase phi MFS_1 PF07690.16 OAG36777.1 - 4e-33 114.8 36.7 2.9e-23 82.4 20.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG36777.1 - 2.9e-07 29.7 16.5 4.4e-06 25.8 1.4 3.6 3 0 0 3 3 3 2 Sugar (and other) transporter MFS_1_like PF12832.7 OAG36777.1 - 4.1e-06 25.9 11.1 0.0011 17.9 1.3 2.5 2 1 0 2 2 2 2 MFS_1 like family MFS_2 PF13347.6 OAG36777.1 - 7.4e-05 21.5 19.5 0.027 13.0 6.1 3.2 1 1 2 3 3 3 2 MFS/sugar transport protein DUF998 PF06197.13 OAG36777.1 - 0.42 10.2 18.7 0.086 12.4 10.0 3.2 2 2 0 2 2 2 0 Protein of unknown function (DUF998) UNC-93 PF05978.16 OAG36777.1 - 7.7 6.2 8.7 0.11 12.1 0.5 2.1 3 0 0 3 3 3 0 Ion channel regulatory protein UNC-93 DUF4233 PF14017.6 OAG36777.1 - 7.8 6.9 11.3 2.7 8.4 5.2 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4233) ADH_zinc_N PF00107.26 OAG36778.1 - 6.5e-19 68.2 0.2 1.1e-18 67.4 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAG36778.1 - 8.7e-16 59.2 0.0 1.9e-15 58.1 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG36778.1 - 3.4e-06 26.9 0.0 6e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ELFV_dehydrog PF00208.21 OAG36778.1 - 0.11 12.1 0.3 0.31 10.7 0.0 1.8 2 0 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Mpv17_PMP22 PF04117.12 OAG36779.1 - 6.6e-12 45.5 0.2 6.6e-12 45.5 0.2 1.7 2 0 0 2 2 2 1 Mpv17 / PMP22 family V_ATPase_I PF01496.19 OAG36779.1 - 0.065 11.2 0.0 0.077 10.9 0.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3381 PF11861.8 OAG36779.1 - 0.21 11.4 4.1 0.3 10.9 4.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) PSI PF01437.25 OAG36780.1 - 0.0066 17.0 9.9 0.011 16.3 9.9 1.5 1 1 0 1 1 1 1 Plexin repeat DUF3237 PF11578.8 OAG36781.1 - 2.2e-09 37.3 0.0 2.7e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) GEN1_C PF18380.1 OAG36782.1 - 0.57 11.1 5.3 0.92 10.4 1.6 2.5 2 0 0 2 2 2 0 Holliday junction resolvase Gen1 C-terminal domain Fungal_trans PF04082.18 OAG36783.1 - 4e-20 72.0 0.9 6.1e-20 71.4 0.9 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG36783.1 - 1.6e-08 34.5 9.3 3.1e-08 33.6 9.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAG36784.1 - 7.5e-15 54.7 0.0 1.4e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Trimer_CC PF08954.11 OAG36784.1 - 0.022 14.3 0.1 0.059 12.9 0.1 1.7 1 0 0 1 1 1 0 Trimerisation motif DUF4078 PF13300.6 OAG36784.1 - 0.025 14.9 0.1 0.059 13.7 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4078) zf-C2H2 PF00096.26 OAG36786.1 - 3.9 8.1 9.9 0.45 11.1 4.7 2.3 2 0 0 2 2 2 0 Zinc finger, C2H2 type Thiolase_N PF00108.23 OAG36787.1 - 6.9e-10 38.7 0.0 2.4e-08 33.6 0.0 2.7 2 1 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 OAG36787.1 - 2.4e-09 36.9 1.4 4.7e-08 32.7 0.0 3.3 2 1 1 4 4 4 1 Thiolase, C-terminal domain ACP_syn_III PF08545.10 OAG36787.1 - 1.2e-05 25.1 0.0 0.0013 18.5 0.0 2.5 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.26 OAG36787.1 - 0.0082 15.7 0.1 0.058 13.0 0.1 2.1 1 1 1 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain DUF3208 PF11482.8 OAG36787.1 - 0.024 14.9 0.0 0.11 12.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3208) SpoVAD PF07451.11 OAG36787.1 - 0.038 12.7 0.0 0.078 11.7 0.0 1.4 1 0 0 1 1 1 0 Stage V sporulation protein AD (SpoVAD) Fungal_trans PF04082.18 OAG36789.1 - 2.3e-08 33.4 0.0 4.3e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans_2 PF11951.8 OAG36789.1 - 0.1 11.4 3.3 4.1 6.1 0.9 2.7 1 1 1 3 3 3 0 Fungal specific transcription factor domain IDO PF01231.18 OAG36790.1 - 1.7e-147 491.7 0.0 1.9e-147 491.6 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase NAD_binding_6 PF08030.12 OAG36791.1 - 1.1e-15 58.1 0.0 2e-15 57.2 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 OAG36791.1 - 2.3e-09 37.3 0.0 0.0033 17.5 0.0 2.4 2 0 0 2 2 2 2 FAD-binding domain Ferric_reduct PF01794.19 OAG36791.1 - 4.3e-06 26.9 7.2 4.3e-06 26.9 7.2 1.8 2 0 0 2 2 2 1 Ferric reductase like transmembrane component DUF359 PF04019.12 OAG36791.1 - 0.13 11.9 0.0 0.88 9.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF359) Fasciclin PF02469.22 OAG36792.1 - 5.5e-31 107.5 0.0 2.9e-18 66.3 0.0 2.2 2 0 0 2 2 2 2 Fasciclin domain DUF1572 PF07609.11 OAG36792.1 - 0.13 12.0 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1572) Adeno_PIX PF03955.14 OAG36792.1 - 2.5 8.3 9.3 0.46 10.7 2.5 2.9 3 0 0 3 3 3 0 Adenovirus hexon-associated protein (IX) DUF3425 PF11905.8 OAG36793.1 - 5e-08 33.0 0.0 1.1e-07 31.8 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3425) Oxidored_FMN PF00724.20 OAG36794.1 - 1.9e-31 109.6 0.0 2.4e-31 109.3 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Sugar_tr PF00083.24 OAG36795.1 - 1.2e-68 232.1 24.6 1.1e-67 228.9 24.6 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG36795.1 - 4.6e-10 39.0 40.1 5.7e-10 38.6 29.5 3.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF502 PF04367.13 OAG36795.1 - 0.2 11.6 1.6 0.28 11.1 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF502) Fungal_trans PF04082.18 OAG36796.1 - 4.9e-18 65.1 2.6 7.2e-18 64.6 2.6 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain UBA PF00627.31 OAG36796.1 - 0.085 12.8 0.4 0.24 11.4 0.4 1.7 1 0 0 1 1 1 0 UBA/TS-N domain HpcH_HpaI PF03328.14 OAG36797.1 - 6.9e-39 133.3 0.0 8.1e-39 133.0 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family GMC_oxred_N PF00732.19 OAG36800.1 - 3.9e-63 213.6 0.0 5.6e-63 213.1 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAG36800.1 - 1.1e-32 113.5 0.0 2e-32 112.7 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 OAG36800.1 - 3.1e-05 23.2 0.1 5.5e-05 22.4 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 OAG36800.1 - 0.00043 19.5 0.4 0.062 12.4 0.2 2.2 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.17 OAG36800.1 - 0.00077 18.8 0.0 0.0017 17.6 0.0 1.5 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 OAG36800.1 - 0.0023 17.6 1.2 1.1 8.8 0.6 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG36800.1 - 0.017 14.4 0.1 0.043 13.1 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG36800.1 - 0.022 15.0 0.1 0.057 13.7 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 OAG36800.1 - 0.038 13.3 0.1 2.1 7.6 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase Mqo PF06039.15 OAG36800.1 - 0.11 11.1 0.1 0.65 8.5 0.1 1.9 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) FAD_binding_3 PF01494.19 OAG36800.1 - 0.12 11.6 0.3 0.22 10.7 0.3 1.4 1 0 0 1 1 1 0 FAD binding domain Sortilin-Vps10 PF15902.5 OAG36801.1 - 0.15 10.8 0.0 0.24 10.2 0.0 1.3 1 0 0 1 1 1 0 Sortilin, neurotensin receptor 3, adh_short_C2 PF13561.6 OAG36802.1 - 6e-62 209.3 0.1 7.2e-62 209.0 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG36802.1 - 8.4e-56 188.5 0.5 9.9e-56 188.3 0.5 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG36802.1 - 7.9e-13 48.7 0.3 1.7e-12 47.6 0.2 1.6 1 1 1 2 2 2 2 KR domain 3Beta_HSD PF01073.19 OAG36802.1 - 0.00085 18.4 0.2 0.0012 18.0 0.2 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 OAG36802.1 - 0.0037 16.8 0.1 0.0086 15.6 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family HHH_5 PF14520.6 OAG36802.1 - 0.14 12.7 0.6 11 6.7 0.1 2.5 2 0 0 2 2 2 0 Helix-hairpin-helix domain Sugar_tr PF00083.24 OAG36803.1 - 3e-38 131.9 21.0 3.2e-26 92.2 2.8 2.3 3 0 0 3 3 3 2 Sugar (and other) transporter MFS_1 PF07690.16 OAG36803.1 - 1.3e-21 76.9 21.9 1.3e-21 76.9 21.9 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily zf-C2H2_4 PF13894.6 OAG36804.1 - 4.5 8.4 11.0 16 6.6 0.8 3.8 3 0 0 3 3 3 0 C2H2-type zinc finger efThoc1 PF11957.8 OAG36805.1 - 8.8e-137 456.7 0.0 1.1e-136 456.3 0.0 1.1 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor Aquarius_N PF16399.5 OAG36806.1 - 8e-294 976.7 0.0 1e-293 976.4 0.0 1.1 1 0 0 1 1 1 1 Intron-binding protein aquarius N-terminus AAA_12 PF13087.6 OAG36806.1 - 9.1e-26 90.7 0.0 1.7e-25 89.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 OAG36806.1 - 7.9e-22 78.3 0.0 3.7e-21 76.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OAG36806.1 - 8.2e-07 29.5 0.0 2.9e-06 27.7 0.0 2.0 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 OAG36806.1 - 2.2e-06 27.8 0.0 7.3e-06 26.1 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 OAG36806.1 - 3.5e-06 26.9 0.0 0.00052 19.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OAG36806.1 - 0.0013 19.2 0.7 0.016 15.6 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain UvrD-helicase PF00580.21 OAG36806.1 - 0.0062 16.1 0.0 0.013 15.0 0.0 1.5 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain Parvo_NS1 PF01057.17 OAG36806.1 - 0.01 14.9 0.0 0.019 14.1 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA PF00004.29 OAG36806.1 - 0.011 16.2 0.0 0.062 13.7 0.0 2.4 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) UvrD_C_2 PF13538.6 OAG36806.1 - 0.037 13.8 3.2 0.066 13.1 0.2 2.7 3 0 0 3 3 3 0 UvrD-like helicase C-terminal domain AAA_5 PF07728.14 OAG36806.1 - 0.049 13.6 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Viral_helicase1 PF01443.18 OAG36806.1 - 0.08 12.7 0.1 2.6 7.7 0.1 2.9 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase Adeno_IVa2 PF02456.15 OAG36806.1 - 0.086 11.6 0.4 7.1 5.3 0.1 2.2 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_22 PF13401.6 OAG36806.1 - 0.09 13.1 0.0 0.3 11.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain DnaB_C PF03796.15 OAG36806.1 - 0.1 11.9 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain PFK PF00365.20 OAG36807.1 - 4e-192 636.7 0.6 2.1e-105 352.1 0.3 2.1 2 0 0 2 2 2 2 Phosphofructokinase DAGK_cat PF00781.24 OAG36807.1 - 0.07 12.7 0.1 0.2 11.3 0.1 1.8 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain UVR PF02151.19 OAG36807.1 - 0.2 11.5 0.6 0.54 10.1 0.6 1.8 1 0 0 1 1 1 0 UvrB/uvrC motif Med17 PF10156.9 OAG36808.1 - 1.2e-84 284.7 0.0 2.4e-84 283.7 0.0 1.4 1 0 0 1 1 1 1 Subunit 17 of Mediator complex Fungal_trans PF04082.18 OAG36808.1 - 2.3e-19 69.5 0.0 4.1e-19 68.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain ADH_N PF08240.12 OAG36809.1 - 7.5e-09 35.5 0.0 1.6e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG36809.1 - 3.1e-07 30.4 0.1 5.8e-07 29.6 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 OAG36809.1 - 0.00025 20.5 0.4 0.0004 19.9 0.4 1.3 1 0 0 1 1 1 1 short chain dehydrogenase ISN1 PF06437.11 OAG36810.1 - 1.6e-172 574.0 0.0 2e-172 573.7 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase Rad21_Rec8 PF04824.16 OAG36810.1 - 0.063 12.6 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 Conserved region of Rad21 / Rec8 like protein Adaptin_N PF01602.20 OAG36811.1 - 1.9e-126 422.7 6.4 2.4e-126 422.4 6.4 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 OAG36811.1 - 1.5e-44 150.8 0.0 4.6e-44 149.2 0.0 1.9 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.20 OAG36811.1 - 3.7e-17 62.6 0.0 7.4e-17 61.7 0.0 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 OAG36811.1 - 0.00089 19.3 0.7 0.052 13.6 0.0 3.0 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 OAG36811.1 - 0.0079 16.4 0.7 0.2 11.8 0.1 3.5 4 0 0 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 Ala_racemase_N PF01168.20 OAG36812.1 - 1.5e-19 70.5 0.1 5.3e-19 68.7 0.0 1.8 2 0 0 2 2 2 1 Alanine racemase, N-terminal domain ABC_tran PF00005.27 OAG36813.1 - 1.4e-48 164.9 0.1 5.5e-26 91.7 0.0 4.2 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 OAG36813.1 - 4.6e-13 49.6 6.1 0.0021 17.9 0.0 4.4 2 2 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OAG36813.1 - 4.5e-12 45.9 0.1 0.0022 17.5 0.0 4.1 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 OAG36813.1 - 2.8e-08 34.5 1.8 0.00049 20.7 0.1 2.6 3 0 0 3 3 2 2 AAA domain MMR_HSR1 PF01926.23 OAG36813.1 - 1.9e-07 31.2 0.0 0.0024 17.9 0.0 3.1 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OAG36813.1 - 4.5e-07 29.9 0.2 0.0029 17.5 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 OAG36813.1 - 7.7e-07 28.8 0.5 0.011 15.5 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Chromo PF00385.24 OAG36813.1 - 1.2e-06 28.4 0.4 2.3e-06 27.4 0.4 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_28 PF13521.6 OAG36813.1 - 2.7e-05 24.5 0.0 0.0042 17.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 OAG36813.1 - 0.00014 21.8 0.2 0.55 10.1 0.0 3.6 3 0 0 3 3 3 1 NACHT domain AAA_22 PF13401.6 OAG36813.1 - 0.00014 22.1 0.2 0.77 10.0 0.1 3.0 2 1 0 2 2 2 2 AAA domain AAA_18 PF13238.6 OAG36813.1 - 0.00015 22.3 0.1 0.12 12.9 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_15 PF13175.6 OAG36813.1 - 0.00017 21.5 0.2 0.21 11.2 0.2 2.4 2 0 0 2 2 2 2 AAA ATPase domain DUF87 PF01935.17 OAG36813.1 - 0.00019 21.6 0.3 0.11 12.5 0.1 3.0 2 0 0 2 2 2 1 Helicase HerA, central domain MeaB PF03308.16 OAG36813.1 - 0.00032 19.8 0.3 0.11 11.4 0.1 2.5 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB CLASP_N PF12348.8 OAG36813.1 - 0.00033 20.3 0.0 0.019 14.6 0.0 2.5 2 0 0 2 2 2 1 CLASP N terminal AAA_13 PF13166.6 OAG36813.1 - 0.0037 16.0 0.0 1.4 7.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 OAG36813.1 - 0.0041 17.3 0.0 5.7 7.1 0.0 2.9 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 OAG36813.1 - 0.0068 16.8 0.1 5.5 7.4 0.0 2.8 2 0 0 2 2 2 0 RNA helicase SR-25 PF10500.9 OAG36813.1 - 0.0068 16.0 1.2 0.013 15.2 1.2 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein AAA_14 PF13173.6 OAG36813.1 - 0.009 16.0 0.0 6.1 6.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF3584 PF12128.8 OAG36813.1 - 0.0091 13.6 1.2 0.61 7.5 0.1 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3584) Dynamin_N PF00350.23 OAG36813.1 - 0.011 15.8 0.0 0.27 11.3 0.0 2.8 2 1 0 2 2 2 0 Dynamin family AAA_30 PF13604.6 OAG36813.1 - 0.012 15.4 0.4 9.8 5.8 0.0 3.2 3 0 0 3 3 2 0 AAA domain DUF815 PF05673.13 OAG36813.1 - 0.013 14.7 0.4 0.44 9.7 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_27 PF13514.6 OAG36813.1 - 0.02 14.5 0.7 11 5.6 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.6 OAG36813.1 - 0.024 14.4 0.5 1.9 8.2 0.1 2.6 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 OAG36813.1 - 0.025 14.3 0.1 0.78 9.5 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Roc PF08477.13 OAG36813.1 - 0.029 14.6 0.1 5.7 7.2 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 OAG36813.1 - 0.036 14.5 0.2 4.2 7.7 0.0 3.0 4 0 0 4 4 2 0 AAA ATPase domain HEAT PF02985.22 OAG36813.1 - 0.038 14.3 0.0 89 3.8 0.0 4.9 5 0 0 5 5 4 0 HEAT repeat NB-ARC PF00931.22 OAG36813.1 - 0.046 12.9 0.8 8.1 5.5 0.0 3.2 3 0 0 3 3 3 0 NB-ARC domain Zeta_toxin PF06414.12 OAG36813.1 - 0.049 12.9 1.1 4.4 6.5 0.1 3.1 3 0 0 3 3 3 0 Zeta toxin AAA PF00004.29 OAG36813.1 - 0.06 13.8 0.0 14 6.1 0.0 3.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Ploopntkinase3 PF18751.1 OAG36813.1 - 0.076 12.9 0.0 20 5.0 0.0 2.6 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 Septin PF00735.18 OAG36813.1 - 0.082 12.2 0.0 6.9 5.9 0.0 2.4 2 0 0 2 2 2 0 Septin TsaE PF02367.17 OAG36813.1 - 0.13 12.3 0.4 14 5.7 0.1 2.8 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ICL PF00463.21 OAG36814.1 - 1.6e-189 630.8 0.0 1.8e-189 630.6 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 OAG36814.1 - 3.5e-08 33.2 0.0 5.9e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase AIB PF15334.6 OAG36814.1 - 0.13 11.6 0.0 0.27 10.5 0.0 1.5 1 0 0 1 1 1 0 Aurora kinase A and ninein interacting protein Citrate_synt PF00285.21 OAG36815.1 - 3.2e-94 316.0 0.0 4.1e-94 315.6 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Glyco_hydro_16 PF00722.21 OAG36816.1 - 1.6e-17 63.5 0.8 2.6e-17 62.9 0.8 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Glyco_trans_2_3 PF13632.6 OAG36817.1 - 3.3e-52 177.3 2.4 8.1e-52 176.0 2.4 1.7 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 OAG36817.1 - 9.1e-06 25.6 0.0 5.9e-05 22.9 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 OAG36817.1 - 0.0032 17.0 0.0 0.0059 16.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 OAG36817.1 - 0.16 11.9 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase like family 2 ADH_zinc_N PF00107.26 OAG36818.1 - 9.9e-29 99.9 1.2 9.9e-29 99.9 0.2 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG36818.1 - 3.8e-23 81.4 0.3 7.8e-23 80.4 0.3 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 OAG36818.1 - 0.00039 21.5 0.1 0.00065 20.8 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 OAG36818.1 - 0.0044 16.9 0.1 0.021 14.7 0.0 2.2 2 1 0 2 2 2 1 N-terminal domain of oxidoreductase AlaDh_PNT_C PF01262.21 OAG36818.1 - 0.016 14.5 0.4 0.026 13.8 0.4 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain adh_short PF00106.25 OAG36818.1 - 0.021 14.3 0.3 0.038 13.4 0.3 1.4 1 0 0 1 1 1 0 short chain dehydrogenase EBP PF05241.12 OAG36818.1 - 0.17 11.4 0.0 0.25 10.8 0.0 1.2 1 0 0 1 1 1 0 Emopamil binding protein CN_hydrolase PF00795.22 OAG36819.1 - 7.2e-46 156.6 0.0 8.7e-46 156.4 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase MFS_1 PF07690.16 OAG36820.1 - 2.2e-38 132.1 46.0 1.3e-36 126.3 39.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG36820.1 - 6.3e-10 38.5 14.3 6.3e-10 38.5 14.3 2.8 2 1 1 3 3 3 1 Sugar (and other) transporter Sugar_tr PF00083.24 OAG36821.1 - 7.8e-84 282.1 20.3 8.9e-84 281.9 20.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG36821.1 - 1.6e-23 83.2 33.0 1.5e-18 66.9 14.9 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.18 OAG36822.1 - 1.5e-09 37.3 0.0 3.4e-09 36.1 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG36822.1 - 0.00017 21.7 7.3 0.0004 20.5 7.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_2 PF07719.17 OAG36823.1 - 2.6e-12 45.8 12.6 8.8e-07 28.6 0.1 5.9 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 OAG36823.1 - 1.3e-08 34.3 5.0 3.1e-06 26.7 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 OAG36823.1 - 4.3e-06 26.3 1.2 0.0041 16.8 0.0 4.8 6 0 0 6 6 6 1 TPR repeat TPR_19 PF14559.6 OAG36823.1 - 2.7e-05 24.6 7.0 0.0039 17.6 0.1 4.8 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 OAG36823.1 - 6.6e-05 22.8 4.5 0.0059 16.7 0.0 5.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 OAG36823.1 - 0.0064 16.4 0.9 1.1 9.5 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 OAG36823.1 - 0.0081 16.5 5.7 2.8 8.5 0.0 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 OAG36823.1 - 0.017 15.9 14.6 3.8 8.6 0.2 6.2 6 1 1 7 7 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 OAG36823.1 - 0.026 14.8 7.2 0.93 9.8 0.7 4.4 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 OAG36823.1 - 0.86 10.3 18.7 1.5 9.5 0.1 6.1 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_4 PF07721.14 OAG36823.1 - 2.2 9.1 8.4 16 6.5 0.3 4.5 4 0 0 4 4 3 0 Tetratricopeptide repeat Sugar_tr PF00083.24 OAG36825.1 - 2e-88 297.3 20.2 2.3e-88 297.0 20.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG36825.1 - 1.2e-25 90.2 52.2 1.3e-22 80.3 28.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 OAG36825.1 - 6e-05 21.7 0.6 6e-05 21.7 0.6 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) TMEM144 PF07857.12 OAG36825.1 - 0.00029 19.9 0.6 0.00074 18.6 0.6 1.6 1 0 0 1 1 1 1 Transmembrane family, TMEM144 of transporters BT1 PF03092.16 OAG36825.1 - 0.2 9.9 11.1 0.26 9.5 0.2 4.0 4 1 0 5 5 5 0 BT1 family Aconitase PF00330.20 OAG36826.1 - 5.1e-70 236.7 0.1 4.6e-69 233.6 0.1 1.9 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 OAG36826.1 - 5.5e-19 68.8 0.0 9.8e-19 68.0 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF4950 PF16308.5 OAG36828.1 - 0.0029 17.6 0.2 0.0046 17.0 0.1 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4950) Cadherin_4 PF17803.1 OAG36828.1 - 0.18 12.5 1.9 0.31 11.7 1.9 1.4 1 0 0 1 1 1 0 Bacterial cadherin-like domain ACOX PF01756.19 OAG36829.1 - 8.6e-43 146.0 1.9 1.1e-42 145.6 0.8 1.7 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 OAG36829.1 - 1.2e-24 87.2 0.2 3.1e-24 85.9 0.2 1.8 2 0 0 2 2 2 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 OAG36829.1 - 1.4e-08 34.8 0.0 3e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 OAG36829.1 - 0.016 15.4 2.1 0.84 9.8 2.1 2.5 1 1 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain MFS_1 PF07690.16 OAG36830.1 - 4.3e-29 101.5 28.8 4.3e-29 101.5 28.8 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily AMP-binding PF00501.28 OAG36831.1 - 1.3e-52 178.9 0.0 1.6e-52 178.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG36831.1 - 1e-13 52.1 0.2 1.7e-12 48.1 0.0 2.6 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ECH_1 PF00378.20 OAG36832.1 - 3e-31 108.6 0.0 3.4e-31 108.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAG36832.1 - 1.9e-13 50.7 0.0 2.1e-13 50.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Acyl-CoA_ox_N PF14749.6 OAG36833.1 - 2.1e-20 73.5 1.2 5e-20 72.3 1.2 1.7 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal ACOX PF01756.19 OAG36833.1 - 2e-14 53.5 0.5 6.5e-14 51.9 0.1 1.9 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.19 OAG36833.1 - 7.2e-10 38.9 0.0 1.7e-09 37.7 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 OAG36833.1 - 0.0023 18.2 0.0 0.0046 17.2 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Fuseless PF15993.5 OAG36833.1 - 0.023 13.9 0.0 0.038 13.2 0.0 1.2 1 0 0 1 1 1 0 Fuseless Fungal_trans PF04082.18 OAG36834.1 - 3.1e-09 36.3 0.1 6.5e-09 35.2 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain HLH PF00010.26 OAG36835.1 - 1.2e-05 25.1 1.1 1.2e-05 25.1 1.1 2.9 3 1 0 3 3 3 1 Helix-loop-helix DNA-binding domain DUF1664 PF07889.12 OAG36835.1 - 0.022 14.8 0.4 0.04 13.9 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Papilin_u7 PF16626.5 OAG36835.1 - 0.025 15.2 0.9 0.044 14.4 0.9 1.4 1 0 0 1 1 1 0 Linking region between Kunitz_BPTI and I-set on papilin Abhydrolase_6 PF12697.7 OAG36836.1 - 1.9e-05 25.4 0.9 2.7e-05 24.9 0.9 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF1749 PF08538.10 OAG36836.1 - 0.052 12.6 0.0 1.1 8.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1749) ANAPC4 PF12896.7 OAG36837.1 - 0.01 15.4 0.5 2.3 7.7 0.3 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 4 adh_short PF00106.25 OAG36838.1 - 1.2e-23 83.6 0.0 8.5e-21 74.3 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAG36838.1 - 5.1e-15 55.7 0.0 6e-12 45.6 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG36838.1 - 1.1e-11 45.0 0.1 1.6e-11 44.4 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG36838.1 - 1.6e-06 27.8 0.1 2.5e-06 27.1 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAG36838.1 - 0.0043 16.5 0.0 0.0097 15.3 0.0 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase YjeF_N PF03853.15 OAG36838.1 - 0.0095 15.8 0.1 0.017 15.0 0.1 1.3 1 0 0 1 1 1 1 YjeF-related protein N-terminus Polysacc_synt_2 PF02719.15 OAG36838.1 - 0.01 15.0 0.0 0.016 14.4 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Amidase PF01425.21 OAG36839.1 - 1.4e-74 251.7 0.0 1.1e-73 248.8 0.0 1.9 1 1 0 1 1 1 1 Amidase DNA_ligase_A_M PF01068.21 OAG36840.1 - 3.8e-51 173.6 0.6 3.2e-48 164.1 0.0 2.3 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 OAG36840.1 - 8.5e-36 123.9 0.0 1.7e-35 122.9 0.0 1.6 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 OAG36840.1 - 4.8e-20 72.0 0.5 3e-19 69.5 0.0 2.7 3 0 0 3 3 3 1 ATP dependent DNA ligase C terminal region mRNA_cap_enzyme PF01331.19 OAG36840.1 - 0.082 12.7 0.0 8.4 6.2 0.0 2.4 2 0 0 2 2 2 0 mRNA capping enzyme, catalytic domain RINT1_TIP1 PF04437.13 OAG36841.1 - 8.2e-157 523.1 0.0 1.7e-156 522.0 0.0 1.5 1 0 0 1 1 1 1 RINT-1 / TIP-1 family Clusterin PF01093.17 OAG36841.1 - 0.051 12.6 4.1 0.088 11.8 2.7 1.9 2 0 0 2 2 2 0 Clusterin ISG65-75 PF11727.8 OAG36841.1 - 0.17 11.1 2.8 0.31 10.2 2.8 1.4 1 0 0 1 1 1 0 Invariant surface glycoprotein Prominin PF05478.11 OAG36841.1 - 0.17 9.8 3.5 0.28 9.1 3.5 1.3 1 0 0 1 1 1 0 Prominin Vps54_N PF10475.9 OAG36841.1 - 0.51 9.6 4.2 1.1 8.4 4.2 1.5 1 0 0 1 1 1 0 Vacuolar-sorting protein 54, of GARP complex Snapin_Pallidin PF14712.6 OAG36841.1 - 1 9.8 5.9 1.8 9.0 3.6 2.7 1 1 0 2 2 2 0 Snapin/Pallidin Nup54 PF13874.6 OAG36841.1 - 2.7 8.1 16.0 0.86 9.7 11.4 2.5 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 ELO PF01151.18 OAG36842.1 - 2.6e-12 46.8 3.3 3.6e-12 46.3 3.3 1.2 1 0 0 1 1 1 1 GNS1/SUR4 family Aldedh PF00171.22 OAG36843.1 - 7.6e-160 532.4 0.0 8.5e-160 532.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family FAD_binding_3 PF01494.19 OAG36844.1 - 3.4e-18 66.0 0.0 7.1e-18 65.0 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 OAG36844.1 - 4.3e-08 32.7 0.7 2.7e-07 30.1 0.7 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OAG36844.1 - 2.8e-05 23.4 1.8 0.00049 19.3 1.8 2.1 1 1 0 1 1 1 1 Glucose inhibited division protein A DAO PF01266.24 OAG36844.1 - 5e-05 23.1 0.8 0.067 12.8 0.4 2.5 1 1 1 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAG36844.1 - 5.1e-05 23.4 0.1 0.00011 22.4 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 OAG36844.1 - 0.00029 21.3 0.3 0.0036 17.8 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG36844.1 - 0.00051 19.4 0.2 0.052 12.8 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAG36844.1 - 0.001 18.3 0.6 0.0016 17.6 0.6 1.3 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 OAG36844.1 - 0.0012 18.2 0.2 0.0029 16.9 0.2 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 OAG36844.1 - 0.0015 17.3 0.6 0.053 12.2 0.1 2.2 2 0 0 2 2 2 1 HI0933-like protein Amino_oxidase PF01593.24 OAG36844.1 - 0.0037 16.6 0.0 1.3 8.2 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase DUF4140 PF13600.6 OAG36844.1 - 0.029 14.8 0.1 0.06 13.8 0.1 1.5 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Trp_halogenase PF04820.14 OAG36844.1 - 0.041 12.7 0.3 2.8 6.7 0.1 2.1 2 0 0 2 2 2 0 Tryptophan halogenase DUF4349 PF14257.6 OAG36844.1 - 0.092 12.2 0.0 0.23 10.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) NAD_binding_9 PF13454.6 OAG36844.1 - 0.18 11.8 0.5 15 5.6 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding Sugarporin_N PF11471.8 OAG36844.1 - 0.78 9.7 4.3 0.42 10.6 0.1 2.6 3 0 0 3 3 3 0 Maltoporin periplasmic N-terminal extension SH3_15 PF18346.1 OAG36845.1 - 0.11 12.8 0.0 0.31 11.4 0.0 1.7 1 0 0 1 1 1 0 Mind bomb SH3 repeat domain Sel1 PF08238.12 OAG36846.1 - 6.2e-32 109.3 39.5 3.7e-06 27.4 0.3 10.0 11 0 0 11 11 11 6 Sel1 repeat TPR_7 PF13176.6 OAG36846.1 - 1.1e-05 25.1 3.5 2.1 8.6 0.0 5.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 OAG36846.1 - 0.00039 20.4 3.7 23 5.5 0.1 6.5 7 0 0 7 7 7 1 Tetratricopeptide repeat TOM20_plant PF06552.12 OAG36846.1 - 0.073 12.8 0.4 3.8 7.2 0.1 3.1 2 1 1 3 3 3 0 Plant specific mitochondrial import receptor subunit TOM20 TPR_2 PF07719.17 OAG36846.1 - 1.2 9.5 20.9 22 5.5 0.0 8.4 10 0 0 10 10 10 0 Tetratricopeptide repeat SNAP PF14938.6 OAG36846.1 - 4.8 6.5 9.3 0.58 9.5 0.2 3.2 3 0 0 3 3 3 0 Soluble NSF attachment protein, SNAP Med3 PF11593.8 OAG36846.1 - 8.3 5.5 14.1 15 4.7 14.1 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal PET117 PF15786.5 OAG36847.1 - 5.3e-25 87.5 2.3 9.1e-25 86.7 2.3 1.4 1 0 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial HD_4 PF13328.6 OAG36847.1 - 0.071 12.8 0.6 0.12 12.1 0.5 1.3 1 1 0 1 1 1 0 HD domain V-ATPase_G PF03179.15 OAG36848.1 - 1.2e-24 86.9 17.8 5e-19 68.8 10.6 2.1 2 0 0 2 2 2 2 Vacuolar (H+)-ATPase G subunit V-ATPase_G_2 PF16999.5 OAG36848.1 - 0.11 12.9 9.3 1.3 9.5 8.1 2.1 2 0 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit AAA_15 PF13175.6 OAG36848.1 - 0.13 11.9 7.5 0.15 11.7 7.5 1.1 1 0 0 1 1 1 0 AAA ATPase domain DUF853 PF05872.12 OAG36848.1 - 0.48 9.0 3.6 0.58 8.7 3.6 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) RRF PF01765.19 OAG36848.1 - 4.2 7.3 16.6 9.4 6.2 16.4 1.6 1 1 1 2 2 2 0 Ribosome recycling factor V_ATPase_I PF01496.19 OAG36848.1 - 6.2 4.6 6.2 11 3.8 6.5 1.3 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Palm_thioest PF02089.15 OAG36849.1 - 6.6e-07 29.4 0.0 9.2e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_6 PF12697.7 OAG36849.1 - 0.00021 22.0 0.7 0.00028 21.6 0.7 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 OAG36849.1 - 0.00034 20.4 0.0 0.00068 19.4 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.14 OAG36849.1 - 0.00044 19.8 0.0 0.00078 19.0 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_1 PF00561.20 OAG36849.1 - 0.011 15.4 0.1 0.21 11.2 0.0 2.4 3 0 0 3 3 3 0 alpha/beta hydrolase fold LCAT PF02450.15 OAG36849.1 - 0.2 10.8 0.0 0.68 9.0 0.0 1.7 2 0 0 2 2 2 0 Lecithin:cholesterol acyltransferase ECH_1 PF00378.20 OAG36851.1 - 8.3e-23 81.0 0.0 1.4e-20 73.7 0.0 2.8 2 1 0 2 2 2 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAG36851.1 - 5.7e-08 32.6 0.0 6e-06 26.0 0.0 2.5 3 0 0 3 3 3 2 Enoyl-CoA hydratase/isomerase FTH PF01827.27 OAG36851.1 - 0.18 11.6 0.0 0.29 10.9 0.0 1.2 1 0 0 1 1 1 0 FTH domain PIGA PF08288.12 OAG36852.1 - 1.5e-45 153.7 2.3 1.5e-45 153.7 2.3 2.0 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glyco_transf_4 PF13439.6 OAG36852.1 - 6.7e-29 101.1 0.8 1.1e-28 100.4 0.8 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 OAG36852.1 - 1.5e-27 96.2 0.0 2.4e-27 95.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 OAG36852.1 - 3.2e-24 85.9 0.2 6.5e-24 84.9 0.2 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 OAG36852.1 - 2.2e-12 47.7 0.0 4.4e-12 46.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 OAG36852.1 - 8.3e-06 25.9 0.2 2.3e-05 24.5 0.1 1.7 2 0 0 2 2 2 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.6 OAG36852.1 - 0.0063 16.9 0.0 0.032 14.6 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 OAG36852.1 - 0.053 13.2 0.1 0.29 10.8 0.0 2.1 1 1 1 2 2 2 0 Starch synthase catalytic domain Asparaginase_C PF17763.1 OAG36852.1 - 0.054 13.7 0.0 3.2 8.0 0.0 3.2 3 1 1 4 4 4 0 Glutaminase/Asparaginase C-terminal domain DEAD PF00270.29 OAG36853.1 - 1e-33 116.6 0.0 5.2e-16 58.9 0.0 2.6 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 OAG36853.1 - 2.7e-18 66.3 0.0 8.7e-18 64.7 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG36853.1 - 4e-07 30.2 0.0 5.5e-06 26.5 0.0 2.5 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 OAG36853.1 - 0.015 15.6 0.0 0.038 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain UTP25 PF06862.12 OAG36853.1 - 0.1 11.3 0.0 0.48 9.1 0.0 1.9 2 0 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 CMS1 PF14617.6 OAG36853.1 - 0.91 8.8 0.0 0.91 8.8 0.0 3.5 3 0 0 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit SOTI PF17079.5 OAG36853.1 - 1.8 9.0 3.8 28 5.2 0.2 2.7 2 0 0 2 2 2 0 Male-specific protein scotti BTB_2 PF02214.22 OAG36854.1 - 4.6e-07 30.1 0.0 0.0028 18.0 0.0 2.5 2 0 0 2 2 2 2 BTB/POZ domain GST_N PF02798.20 OAG36855.1 - 4.4e-13 49.4 0.0 8e-13 48.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OAG36855.1 - 2.2e-08 34.3 0.0 4.1e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 OAG36855.1 - 7.1e-08 32.8 0.0 1.3e-07 31.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAG36855.1 - 2.8e-07 30.5 0.0 6.1e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OAG36855.1 - 6.4e-07 29.5 0.0 1e-06 28.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OAG36855.1 - 7.5e-06 26.1 0.0 1.4e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 OAG36855.1 - 0.01 16.4 0.0 0.023 15.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Acetyltransf_1 PF00583.25 OAG36856.1 - 2.1e-08 34.4 0.0 3e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OAG36856.1 - 1.7e-07 31.5 0.0 2.5e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OAG36856.1 - 2.5e-06 27.5 0.0 4.3e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_5 PF13444.6 OAG36856.1 - 8.9e-05 23.1 0.0 0.00075 20.2 0.0 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAG36856.1 - 0.0016 18.3 0.0 0.0051 16.7 0.0 1.7 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 OAG36856.1 - 0.0019 18.3 0.0 0.0034 17.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 OAG36856.1 - 0.054 13.6 0.0 0.09 12.9 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase GNAT_acetyltran PF12746.7 OAG36856.1 - 0.19 11.3 0.0 0.26 10.8 0.0 1.1 1 0 0 1 1 1 0 GNAT acetyltransferase Methyltr_RsmB-F PF01189.17 OAG36857.1 - 4.5e-20 72.1 0.5 4.8e-12 45.9 0.1 2.9 3 0 0 3 3 3 2 16S rRNA methyltransferase RsmB/F DUF4332 PF14229.6 OAG36857.1 - 0.0089 16.3 0.1 0.021 15.0 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4332) Fungal_trans PF04082.18 OAG36858.1 - 5e-19 68.4 1.3 9.7e-19 67.4 0.7 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG36858.1 - 2.9e-09 36.9 7.9 7.9e-09 35.5 7.9 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DM13 PF10517.9 OAG36859.1 - 0.011 16.3 0.0 0.024 15.2 0.0 1.5 1 0 0 1 1 1 0 Electron transfer DM13 BTB PF00651.31 OAG36859.1 - 0.19 12.0 0.0 0.31 11.3 0.0 1.3 1 0 0 1 1 1 0 BTB/POZ domain DUF4738 PF15889.5 OAG36859.1 - 0.2 11.5 0.2 0.44 10.4 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4738) BTB PF00651.31 OAG36860.1 - 0.0027 17.9 0.0 0.0057 16.9 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain PPP4R2 PF09184.11 OAG36861.1 - 1.5 8.4 20.0 2.3 7.7 20.0 1.2 1 0 0 1 1 1 0 PPP4R2 SRP19 PF01922.17 OAG36862.1 - 1.2e-23 83.8 0.0 1.7e-23 83.3 0.0 1.2 1 0 0 1 1 1 1 SRP19 protein FMO-like PF00743.19 OAG36863.1 - 2.1e-14 52.8 0.0 7.8e-13 47.7 0.0 2.7 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OAG36863.1 - 1.9e-13 50.4 0.0 4.5e-13 49.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAG36863.1 - 5.4e-07 29.1 0.0 0.00055 19.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAG36863.1 - 0.00089 19.3 0.0 0.11 12.5 0.0 2.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 OAG36863.1 - 0.0021 17.3 0.0 0.073 12.2 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.22 OAG36863.1 - 0.15 11.2 0.0 0.3 10.1 0.0 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A RhoGAP PF00620.27 OAG36863.1 - 0.18 11.6 0.0 0.31 10.9 0.0 1.3 1 0 0 1 1 1 0 RhoGAP domain PRESAN PF09687.10 OAG36863.1 - 0.19 12.3 1.6 1 9.9 0.0 2.3 2 0 0 2 2 2 0 Plasmodium RESA N-terminal DUF3558 PF12079.8 OAG36864.1 - 7.7 6.5 16.3 0.16 12.0 1.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3558) Fungal_trans_2 PF11951.8 OAG36865.1 - 1.3e-07 30.8 0.0 2.7e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain SCP2 PF02036.17 OAG36866.1 - 7.6e-23 80.9 0.3 8.9e-23 80.7 0.3 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 OAG36866.1 - 3e-05 24.3 0.0 3.4e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal Pkinase PF00069.25 OAG36867.1 - 7.2e-60 202.6 0.0 1e-59 202.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG36867.1 - 2.3e-25 89.3 0.0 3.4e-25 88.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAG36867.1 - 1.9e-08 34.0 0.0 2.7e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OAG36867.1 - 0.0035 16.7 0.0 0.0057 16.0 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OAG36867.1 - 0.11 12.4 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family UQ_con PF00179.26 OAG36868.1 - 7.9e-45 151.9 0.0 8.7e-45 151.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 OAG36868.1 - 0.00051 20.3 0.1 0.00079 19.7 0.1 1.3 1 1 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 OAG36868.1 - 0.0072 16.0 0.0 0.009 15.7 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 OAG36868.1 - 0.011 15.6 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 0 UEV domain Aldo_ket_red PF00248.21 OAG36869.1 - 9.2e-47 159.6 0.0 1.3e-46 159.1 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family HD PF01966.22 OAG36870.1 - 0.00012 22.3 0.0 0.00018 21.7 0.0 1.3 1 0 0 1 1 1 1 HD domain MFS_1 PF07690.16 OAG36871.1 - 4.8e-23 81.6 31.5 4.8e-23 81.6 31.5 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily E1-E2_ATPase PF00122.20 OAG36872.1 - 5.5e-51 172.7 0.9 5.5e-51 172.7 0.9 2.6 4 0 0 4 4 4 1 E1-E2 ATPase HMA PF00403.26 OAG36872.1 - 6.4e-46 154.6 1.2 1.2e-11 44.9 0.0 4.5 4 0 0 4 4 4 4 Heavy-metal-associated domain Hydrolase PF00702.26 OAG36872.1 - 3.6e-36 125.4 0.0 1.1e-35 123.9 0.0 1.9 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase B12-binding PF02310.19 OAG36872.1 - 0.00081 19.4 0.3 2.1 8.4 0.0 4.3 4 0 0 4 4 4 1 B12 binding domain Hydrolase_3 PF08282.12 OAG36872.1 - 0.0079 16.0 0.7 0.18 11.5 0.3 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase zinc_ribbon_12 PF11331.8 OAG36872.1 - 0.042 13.7 0.7 22 4.9 0.0 3.4 3 0 0 3 3 3 0 Probable zinc-ribbon domain CSN7a_helixI PF18392.1 OAG36873.1 - 0.073 13.0 0.6 0.13 12.2 0.6 1.3 1 0 0 1 1 1 0 COP9 signalosome complex subunit 7a helix I domain FoP_duplication PF13865.6 OAG36873.1 - 6.5 7.4 15.7 0.84 10.2 2.2 2.4 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 RGS PF00615.19 OAG36874.1 - 2.5e-12 47.1 0.0 4.6e-09 36.6 0.0 2.2 2 0 0 2 2 2 2 Regulator of G protein signaling domain NMN_transporter PF04973.12 OAG36874.1 - 0.16 11.9 5.4 0.3 11.1 5.4 1.4 1 0 0 1 1 1 0 Nicotinamide mononucleotide transporter Bromodomain PF00439.25 OAG36875.1 - 1e-25 89.6 0.7 1e-25 89.6 0.7 2.0 2 0 0 2 2 2 1 Bromodomain Acetyltransf_1 PF00583.25 OAG36875.1 - 2.1e-08 34.4 0.0 4e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OAG36875.1 - 1.4e-06 28.3 0.0 2.5e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OAG36875.1 - 0.00033 21.0 0.1 0.00059 20.2 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF4218 PF13960.6 OAG36875.1 - 0.072 12.7 0.1 0.29 10.8 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4218) Rad1 PF02144.16 OAG36876.1 - 4.9e-75 252.1 0.0 5.7e-75 251.9 0.0 1.0 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 SLAC1 PF03595.17 OAG36877.1 - 6.2e-82 275.4 51.8 7.2e-82 275.2 51.8 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel COesterase PF00135.28 OAG36878.1 - 1e-71 242.4 0.0 5.5e-71 240.0 0.0 1.8 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAG36878.1 - 3.8e-05 23.7 0.6 0.00036 20.4 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Cupin_2 PF07883.11 OAG36879.1 - 2.2e-11 43.3 0.5 2.2e-11 43.3 0.5 2.4 2 1 0 2 2 2 1 Cupin domain Cupin_1 PF00190.22 OAG36879.1 - 8.6e-07 28.7 0.0 1.2e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.19 OAG36879.1 - 0.00046 20.1 0.1 0.00046 20.1 0.1 2.0 2 0 0 2 2 2 1 AraC-like ligand binding domain FdtA PF05523.11 OAG36879.1 - 0.038 13.7 0.0 0.067 12.9 0.0 1.3 1 0 0 1 1 1 0 WxcM-like, C-terminal JmjC PF02373.22 OAG36879.1 - 0.04 14.3 0.1 0.1 13.0 0.1 1.7 1 1 0 1 1 1 0 JmjC domain, hydroxylase DUF4267 PF14087.6 OAG36880.1 - 2e-13 50.4 2.3 2.7e-13 50.0 2.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) PDEase_II PF02112.15 OAG36881.1 - 1.5e-49 168.9 0.0 1.9e-22 79.8 0.0 3.1 3 0 0 3 3 3 3 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.7 OAG36881.1 - 0.13 11.8 0.0 0.33 10.4 0.0 1.7 2 0 0 2 2 2 0 Beta-lactamase superfamily domain SPRY PF00622.28 OAG36882.1 - 1.2e-19 70.6 0.0 1.9e-19 69.9 0.0 1.3 1 0 0 1 1 1 1 SPRY domain DUF3611 PF12263.8 OAG36882.1 - 0.0045 16.9 0.0 0.007 16.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3611) adh_short_C2 PF13561.6 OAG36883.1 - 7.6e-42 143.5 0.0 1e-40 139.7 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG36883.1 - 3.5e-38 131.0 0.0 1e-36 126.3 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG36883.1 - 4.8e-08 33.1 0.0 6.6e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 KR domain LDcluster4 PF18306.1 OAG36883.1 - 0.046 13.3 0.1 0.074 12.6 0.1 1.3 1 0 0 1 1 1 0 SLOG cluster4 family Polysacc_synt_2 PF02719.15 OAG36883.1 - 0.17 11.0 0.0 0.24 10.5 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein PAP2 PF01569.21 OAG36884.1 - 3.2e-23 82.0 3.0 3.2e-23 82.0 3.0 1.7 2 0 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.6 OAG36884.1 - 1.3 9.6 4.3 0.33 11.5 0.7 1.9 2 0 0 2 2 2 0 PAP2 superfamily C-terminal IRK_N PF08466.10 OAG36884.1 - 2.7 8.2 5.1 21 5.3 2.4 2.6 2 0 0 2 2 2 0 Inward rectifier potassium channel N-terminal NUDIX PF00293.28 OAG36885.1 - 9.3e-12 45.1 0.1 5e-11 42.8 0.0 1.9 2 0 0 2 2 2 1 NUDIX domain Glutaminase PF04960.15 OAG36887.1 - 5.9e-113 376.8 0.3 7.1e-113 376.5 0.3 1.1 1 0 0 1 1 1 1 Glutaminase adh_short_C2 PF13561.6 OAG36888.1 - 2.1e-54 184.6 0.1 1.9e-53 181.4 0.1 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG36888.1 - 2.8e-39 134.6 0.9 1.3e-38 132.4 0.9 1.8 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG36888.1 - 1.2e-07 31.8 0.1 1.6e-07 31.4 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG36888.1 - 0.00011 21.7 0.1 0.00016 21.2 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 OAG36888.1 - 0.012 15.5 0.1 0.018 15.0 0.1 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Peptidase_S78_2 PF14550.6 OAG36888.1 - 0.064 13.4 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 Putative phage serine protease XkdF YjeF_N PF03853.15 OAG36888.1 - 0.073 12.9 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 YjeF-related protein N-terminus VEFS-Box PF09733.9 OAG36889.1 - 0.0064 16.3 0.5 0.014 15.2 0.0 1.8 2 0 0 2 2 2 1 VEFS-Box of polycomb protein Fungal_trans PF04082.18 OAG36889.1 - 0.015 14.3 0.3 0.027 13.5 0.3 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain DUF2347 PF09804.9 OAG36889.1 - 0.091 12.3 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) Gly_transf_sug PF04488.15 OAG36890.1 - 1.4e-07 32.1 0.0 3.6e-07 30.7 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 OAG36890.1 - 0.046 13.0 0.0 0.065 12.5 0.0 1.1 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain CtaG_Cox11 PF04442.14 OAG36891.1 - 1e-57 194.4 0.0 1.2e-57 194.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 MFS_1 PF07690.16 OAG36892.1 - 7.5e-40 136.9 22.9 1.8e-39 135.7 22.9 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG36892.1 - 2.3e-08 33.3 3.5 2.3e-08 33.3 3.5 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 OAG36892.1 - 6.3e-05 22.4 5.4 6.3e-05 22.4 5.4 1.5 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB TRI12 PF06609.13 OAG36892.1 - 0.002 16.7 5.2 0.002 16.7 5.2 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) TPR_12 PF13424.6 OAG36893.1 - 6.1e-10 39.3 5.2 0.00023 21.4 0.0 4.3 4 1 1 5 5 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 OAG36893.1 - 3e-08 34.2 1.6 0.0073 16.9 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat NB-ARC PF00931.22 OAG36893.1 - 4.2e-08 32.7 0.0 1.5e-07 30.9 0.0 1.9 1 0 0 1 1 1 1 NB-ARC domain TPR_1 PF00515.28 OAG36893.1 - 6.1e-08 32.2 0.0 0.55 10.2 0.0 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 OAG36893.1 - 1.6e-06 27.8 8.6 0.27 11.4 0.0 6.3 7 0 0 7 7 7 2 Tetratricopeptide repeat AAA_22 PF13401.6 OAG36893.1 - 0.00032 21.0 0.1 0.0031 17.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain TPR_10 PF13374.6 OAG36893.1 - 0.00037 20.3 0.8 0.076 12.9 0.0 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 OAG36893.1 - 0.00088 19.3 0.2 1 9.8 0.0 4.8 6 0 0 6 6 5 1 Tetratricopeptide repeat AAA_16 PF13191.6 OAG36893.1 - 0.0035 17.8 1.5 0.011 16.2 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain TPR_14 PF13428.6 OAG36893.1 - 0.0036 18.0 6.1 5.6 8.1 0.0 5.6 5 0 0 5 5 5 1 Tetratricopeptide repeat Abhydrolase_6 PF12697.7 OAG36893.1 - 0.0074 16.9 0.0 0.018 15.6 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family IstB_IS21 PF01695.17 OAG36893.1 - 0.059 13.1 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein NACHT PF05729.12 OAG36893.1 - 0.073 13.0 0.0 0.25 11.2 0.0 2.0 2 0 0 2 2 2 0 NACHT domain TPR_19 PF14559.6 OAG36893.1 - 0.12 12.9 0.0 4.2 7.9 0.0 3.4 3 0 0 3 3 2 0 Tetratricopeptide repeat Amidase PF01425.21 OAG36894.1 - 1.8e-27 96.4 0.0 1.5e-26 93.4 0.2 1.9 2 0 0 2 2 2 1 Amidase CorA PF01544.18 OAG36895.1 - 8.1e-10 38.5 0.2 1.6e-09 37.5 0.2 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein MFS_1 PF07690.16 OAG36897.1 - 2.9e-30 105.4 35.1 2.9e-30 105.4 35.1 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily ADH_zinc_N PF00107.26 OAG36898.1 - 7e-22 77.8 0.1 1.1e-21 77.1 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAG36898.1 - 1.8e-15 58.2 0.0 2.9e-15 57.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG36898.1 - 4.8e-09 36.1 0.0 8.2e-08 32.1 0.0 2.3 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain Fungal_trans PF04082.18 OAG36899.1 - 2.5e-13 49.7 3.0 7.6e-12 44.8 0.8 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Pro-kuma_activ PF09286.11 OAG36900.1 - 3.5e-39 134.3 0.2 7.1e-39 133.3 0.2 1.6 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 OAG36900.1 - 4.2e-06 26.2 0.6 0.00016 21.0 0.1 2.6 2 2 0 2 2 2 2 Subtilase family Fungal_trans PF04082.18 OAG36902.1 - 2.1e-10 40.1 0.2 3.7e-10 39.3 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2_jaz PF12171.8 OAG36902.1 - 2.4e-06 27.7 0.9 0.059 13.7 0.0 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 OAG36902.1 - 7.6e-06 26.1 12.7 0.00016 21.9 2.7 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAG36902.1 - 0.00026 21.5 10.0 0.039 14.8 1.4 3.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OAG36902.1 - 0.00064 20.0 0.9 0.00064 20.0 0.9 3.5 4 0 0 4 4 4 1 Zinc-finger double domain zf-met PF12874.7 OAG36902.1 - 0.013 15.9 4.2 0.93 10.0 0.1 2.9 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Crust_neurohorm PF01147.17 OAG36902.1 - 0.043 13.6 0.3 0.2 11.5 0.3 2.2 1 0 0 1 1 1 0 Crustacean CHH/MIH/GIH neurohormone family zf-MYST PF17772.1 OAG36902.1 - 0.079 12.6 1.4 3.6 7.3 0.3 2.7 2 0 0 2 2 2 0 MYST family zinc finger domain GAGA PF09237.11 OAG36902.1 - 0.2 11.5 3.6 1.1 9.1 0.2 2.5 1 1 1 2 2 2 0 GAGA factor zf-Di19 PF05605.12 OAG36902.1 - 4.1 7.8 10.4 0.37 11.1 3.2 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding p450 PF00067.22 OAG36903.1 - 1.4e-75 254.8 0.0 1.6e-75 254.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FlbT PF07378.11 OAG36903.1 - 0.1 12.7 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Flagellar protein FlbT SirB PF04247.12 OAG36904.1 - 0.024 14.7 0.9 2.8 8.0 0.2 2.5 2 0 0 2 2 2 0 Invasion gene expression up-regulator, SirB TRP PF06011.12 OAG36904.1 - 0.25 10.0 2.9 0.2 10.3 0.2 2.0 2 0 0 2 2 2 0 Transient receptor potential (TRP) ion channel Acyl-CoA_dh_1 PF00441.24 OAG36905.1 - 3e-21 76.2 1.1 4.6e-21 75.6 1.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 OAG36905.1 - 1.1e-18 67.9 0.1 6e-18 65.5 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 OAG36905.1 - 1.9e-05 24.8 0.0 4.7e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Gpr1_Fun34_YaaH PF01184.19 OAG36906.1 - 3.6e-27 95.3 19.7 6.7e-19 68.3 3.3 2.1 2 0 0 2 2 2 2 GPR1/FUN34/yaaH family DUF1700 PF08006.11 OAG36906.1 - 2.4 7.7 8.2 4.8 6.7 8.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) MFS_1 PF07690.16 OAG36907.1 - 2.4e-28 99.1 24.7 2.4e-28 99.1 24.7 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 OAG36907.1 - 0.00042 19.7 13.4 0.00083 18.8 6.8 2.3 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB DIOX_N PF14226.6 OAG36908.1 - 2.2e-32 112.3 0.0 3.4e-32 111.6 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OAG36908.1 - 2.7e-22 79.2 0.0 4.6e-22 78.4 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TPR_12 PF13424.6 OAG36909.1 - 7.3e-07 29.4 0.3 0.0034 17.6 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 OAG36909.1 - 1.6e-05 24.6 1.0 0.00079 19.4 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 OAG36909.1 - 6.8e-05 22.5 1.0 0.0023 17.7 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 OAG36909.1 - 0.00011 21.9 0.1 0.019 15.0 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 OAG36909.1 - 0.00012 22.5 0.0 0.0036 17.8 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 OAG36909.1 - 0.0007 19.4 0.5 0.011 15.5 0.1 2.9 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 OAG36909.1 - 0.0097 16.0 0.7 0.052 13.7 0.0 2.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 OAG36909.1 - 0.017 14.8 0.0 0.064 12.9 0.0 2.0 2 0 0 2 2 2 0 TPR repeat TPR_14 PF13428.6 OAG36909.1 - 0.031 15.1 4.7 0.37 11.7 0.1 3.3 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 OAG36909.1 - 0.047 14.3 5.0 1.1 10.0 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 OAG36909.1 - 0.07 13.4 0.1 0.33 11.3 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 OAG36909.1 - 0.094 12.9 0.0 0.72 10.1 0.0 2.3 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 OAG36909.1 - 0.52 11.1 2.7 12 6.8 0.0 3.9 4 1 1 5 5 5 0 Tetratricopeptide repeat PBP PF01161.20 OAG36911.1 - 1.9e-19 70.3 0.1 2.9e-19 69.7 0.1 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Dynamin_M PF01031.20 OAG36912.1 - 2.9e-110 368.0 0.0 5.6e-110 367.0 0.0 1.5 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 OAG36912.1 - 1.4e-56 191.1 0.6 2.6e-56 190.3 0.0 1.8 2 0 0 2 2 2 1 Dynamin family GED PF02212.18 OAG36912.1 - 1.3e-32 111.8 0.6 3.4e-32 110.5 0.6 1.8 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 OAG36912.1 - 0.00012 22.1 0.3 0.0019 18.2 0.3 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF5130 PF17174.4 OAG36912.1 - 0.046 13.9 0.3 1.8 8.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5130) DLIC PF05783.11 OAG36912.1 - 1 8.1 3.8 4.3 6.1 3.0 1.9 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) BRO1 PF03097.18 OAG36914.1 - 9.6e-05 21.3 0.0 0.00017 20.5 0.0 1.3 1 1 0 1 1 1 1 BRO1-like domain HBM PF16591.5 OAG36914.1 - 0.091 12.2 0.3 5.6 6.3 0.1 2.6 3 0 0 3 3 3 0 Helical bimodular sensor domain GFA PF04828.14 OAG36915.1 - 7e-11 42.3 0.2 7e-11 42.3 0.2 1.6 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme ApbA PF02558.16 OAG36917.1 - 9.8e-19 67.5 0.0 1.8e-18 66.7 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA DAO PF01266.24 OAG36917.1 - 4.5e-06 26.5 0.3 1.7e-05 24.6 0.1 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG36917.1 - 9.8e-06 25.0 0.3 9.8e-06 25.0 0.3 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAG36917.1 - 1.1e-05 25.9 0.3 2.9e-05 24.5 0.3 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 OAG36917.1 - 5e-05 23.7 0.2 0.00028 21.3 0.1 2.1 2 0 0 2 2 2 1 Putative NAD(P)-binding Pyr_redox_3 PF13738.6 OAG36917.1 - 6e-05 22.4 1.8 0.0013 18.0 0.5 2.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.17 OAG36917.1 - 0.00012 22.5 1.9 0.00019 22.0 0.4 2.2 2 2 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_8 PF13450.6 OAG36917.1 - 0.00024 21.3 0.9 0.00024 21.3 0.9 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.20 OAG36917.1 - 0.0013 18.8 1.2 0.002 18.2 0.1 1.9 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_Gly3P_dh_N PF01210.23 OAG36917.1 - 0.0024 17.8 0.2 0.0052 16.8 0.0 1.7 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.18 OAG36917.1 - 0.0037 17.2 1.1 0.0079 16.1 1.1 1.7 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 OAG36917.1 - 0.004 16.4 0.7 0.0062 15.8 0.7 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_2 PF03446.15 OAG36917.1 - 0.0057 16.8 0.0 0.011 15.9 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 OAG36917.1 - 0.0096 15.5 0.1 0.018 14.6 0.1 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain UDPG_MGDP_dh_N PF03721.14 OAG36917.1 - 0.016 14.8 0.6 0.029 14.0 0.6 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_binding_2 PF00890.24 OAG36917.1 - 0.018 14.1 0.9 0.018 14.1 0.9 1.5 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.14 OAG36917.1 - 0.03 13.0 0.5 0.053 12.2 0.5 1.4 1 0 0 1 1 1 0 HI0933-like protein XdhC_C PF13478.6 OAG36917.1 - 0.034 14.7 0.0 0.074 13.6 0.0 1.6 1 0 0 1 1 1 0 XdhC Rossmann domain ThiF PF00899.21 OAG36917.1 - 0.044 13.1 0.1 0.081 12.3 0.1 1.4 1 0 0 1 1 1 0 ThiF family Lycopene_cycl PF05834.12 OAG36917.1 - 0.092 11.8 0.8 0.14 11.2 0.8 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 OAG36917.1 - 0.094 12.7 1.1 0.4 10.7 0.6 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding Rossmann-like PF10727.9 OAG36917.1 - 0.23 11.3 4.6 0.058 13.3 1.0 1.9 2 1 0 2 2 1 0 Rossmann-like domain GIDA PF01134.22 OAG36917.1 - 0.26 10.3 1.4 0.37 9.8 1.4 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Pneumo_att_G PF05539.11 OAG36918.1 - 1.6 8.2 6.4 1.9 8.0 6.4 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G F-box-like PF12937.7 OAG36919.1 - 0.0022 17.9 0.0 0.0044 16.9 0.0 1.5 1 0 0 1 1 1 1 F-box-like Ofd1_CTDD PF10637.9 OAG36922.1 - 3.1e-86 288.9 0.0 1.2e-80 270.6 0.0 2.2 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 OAG36922.1 - 1.3e-22 80.3 0.0 4.8e-22 78.4 0.0 2.0 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 OAG36922.1 - 9.9e-13 48.8 0.0 2.4e-12 47.6 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Cupin_2 PF07883.11 OAG36923.1 - 6.1e-10 38.7 0.5 1.3e-09 37.7 0.5 1.5 1 1 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 OAG36923.1 - 4.6e-06 26.3 0.0 5.6e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.19 OAG36923.1 - 0.12 12.2 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 AraC-like ligand binding domain ABC_tran PF00005.27 OAG36924.1 - 3.4e-46 157.1 0.2 7.2e-22 78.4 0.0 3.0 4 0 0 4 4 2 2 ABC transporter ABC_tran_Xtn PF12848.7 OAG36924.1 - 3.1e-21 75.2 4.3 3.1e-21 75.2 4.3 3.7 5 0 0 5 5 3 1 ABC transporter AAA_21 PF13304.6 OAG36924.1 - 4.8e-19 69.3 0.1 0.00032 20.6 0.0 4.3 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OAG36924.1 - 3.5e-10 39.7 0.1 0.25 10.7 0.1 4.3 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_18 PF13238.6 OAG36924.1 - 2.4e-08 34.6 1.2 0.095 13.2 0.0 4.0 4 0 0 4 4 4 3 AAA domain AAA_29 PF13555.6 OAG36924.1 - 8.7e-08 31.8 0.2 0.0086 15.8 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.6 OAG36924.1 - 1.5e-07 31.5 0.0 0.0093 15.7 0.0 3.0 2 1 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 OAG36924.1 - 2.1e-06 27.8 0.1 0.0047 16.8 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 OAG36924.1 - 1e-05 26.0 0.1 0.049 14.0 0.0 2.6 2 1 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 OAG36924.1 - 2.5e-05 24.3 0.0 0.03 14.4 0.1 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_23 PF13476.6 OAG36924.1 - 4.3e-05 24.1 10.2 0.029 14.9 0.1 3.9 5 0 0 5 5 3 2 AAA domain NB-ARC PF00931.22 OAG36924.1 - 9.4e-05 21.7 0.1 0.19 10.9 0.0 3.3 3 0 0 3 3 3 1 NB-ARC domain AAA_22 PF13401.6 OAG36924.1 - 0.00013 22.3 0.0 0.23 11.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 OAG36924.1 - 0.0002 21.3 0.1 0.74 9.7 0.0 2.7 2 0 0 2 2 2 2 NACHT domain AAA PF00004.29 OAG36924.1 - 0.00028 21.3 0.1 0.88 10.0 0.0 3.3 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 OAG36924.1 - 0.00055 20.2 0.2 0.26 11.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 OAG36924.1 - 0.00079 19.4 0.1 2 8.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 OAG36924.1 - 0.0014 18.4 0.1 0.98 9.1 0.0 3.1 2 1 1 3 3 3 1 AAA domain RNA_helicase PF00910.22 OAG36924.1 - 0.0014 18.9 0.6 2.7 8.4 0.0 3.0 3 0 0 3 3 2 1 RNA helicase Roc PF08477.13 OAG36924.1 - 0.0021 18.3 0.1 2.5 8.3 0.2 3.0 2 1 1 3 3 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_27 PF13514.6 OAG36924.1 - 0.0023 17.6 0.0 1.2 8.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 OAG36924.1 - 0.0025 18.0 0.1 0.88 9.7 0.1 2.9 3 0 0 3 3 2 1 AAA domain DUF2813 PF11398.8 OAG36924.1 - 0.007 15.7 0.0 4.4 6.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2813) MCM PF00493.23 OAG36924.1 - 0.017 14.2 0.1 4.4 6.3 0.0 2.3 2 0 0 2 2 2 0 MCM P-loop domain AAA_14 PF13173.6 OAG36924.1 - 0.02 14.9 0.0 7.2 6.6 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 OAG36924.1 - 0.02 15.3 0.1 4 7.9 0.0 3.0 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 OAG36924.1 - 0.033 13.9 0.1 2.6 7.7 0.1 2.9 2 1 0 2 2 2 0 AAA domain Rad17 PF03215.15 OAG36924.1 - 0.034 14.1 0.0 10 6.0 0.0 2.6 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_7 PF12775.7 OAG36924.1 - 0.037 13.5 0.0 1.1 8.8 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region PduV-EutP PF10662.9 OAG36924.1 - 0.053 13.3 0.6 3.8 7.3 0.0 3.0 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation ABC_ATPase PF09818.9 OAG36924.1 - 0.056 12.2 0.0 15 4.3 0.0 3.2 3 1 1 4 4 4 0 Predicted ATPase of the ABC class DUF815 PF05673.13 OAG36924.1 - 0.059 12.5 0.1 5.7 6.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_25 PF13481.6 OAG36924.1 - 0.069 12.7 0.0 3 7.4 0.0 3.1 3 0 0 3 3 3 0 AAA domain NTPase_1 PF03266.15 OAG36924.1 - 0.075 12.9 0.2 2.8 7.8 0.1 2.6 2 0 0 2 2 2 0 NTPase FeoB_N PF02421.18 OAG36924.1 - 0.087 12.3 0.3 5.7 6.4 0.0 3.0 3 0 0 3 3 3 0 Ferrous iron transport protein B DAP3 PF10236.9 OAG36924.1 - 0.088 12.0 0.3 13 4.9 0.0 2.6 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 ATPase_2 PF01637.18 OAG36924.1 - 0.096 12.6 0.3 14 5.5 0.0 2.7 3 0 0 3 3 2 0 ATPase domain predominantly from Archaea IstB_IS21 PF01695.17 OAG36924.1 - 0.11 12.2 0.0 1.7 8.4 0.0 2.7 3 0 0 3 3 2 0 IstB-like ATP binding protein MeaB PF03308.16 OAG36924.1 - 0.15 11.0 0.3 13 4.7 0.0 2.7 2 1 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 OAG36924.1 - 0.19 11.8 1.4 30 4.6 0.0 3.7 2 1 1 3 3 3 0 Dynamin family DUF87 PF01935.17 OAG36924.1 - 0.23 11.5 2.8 21 5.1 0.0 3.4 3 1 1 4 4 3 0 Helicase HerA, central domain MlrC_C PF07171.12 OAG36925.1 - 0.2 11.8 6.6 0.73 10.0 0.8 2.9 2 1 1 3 3 3 0 MlrC C-terminus DUF1298 PF06974.13 OAG36925.1 - 1.7 8.6 25.4 5.9 6.8 3.6 5.3 1 1 2 3 3 3 0 Protein of unknown function (DUF1298) Sugar_tr PF00083.24 OAG36926.1 - 3.3e-85 286.6 19.4 3.7e-85 286.5 19.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG36926.1 - 1.5e-22 80.0 34.5 1.8e-18 66.6 22.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2085 PF09858.9 OAG36926.1 - 1.7 9.2 12.6 10 6.6 0.9 3.8 2 1 1 3 3 3 0 Predicted membrane protein (DUF2085) MFS_1 PF07690.16 OAG36927.1 - 4.5e-15 55.4 29.7 1.1e-14 54.2 29.7 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Cytochrome-c551 PF10643.9 OAG36927.1 - 5.1 6.6 5.6 11 5.6 5.6 1.4 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 TRI12 PF06609.13 OAG36928.1 - 3.4e-28 98.4 19.6 1.5e-27 96.3 19.6 1.7 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) TRI12 PF06609.13 OAG36929.1 - 2.9e-09 35.9 1.4 3.6e-09 35.6 1.4 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG36929.1 - 0.00079 18.4 8.6 0.00092 18.2 8.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG36929.1 - 0.0033 16.4 0.1 0.0033 16.4 0.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter FMO-like PF00743.19 OAG36930.1 - 3.2e-05 22.6 0.3 8.1e-05 21.2 0.0 1.6 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like DIOX_N PF14226.6 OAG36931.1 - 3.7e-19 69.6 0.1 6.4e-19 68.9 0.1 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OAG36931.1 - 1.7e-11 44.5 0.0 3.6e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.16 OAG36932.1 - 2.4e-31 109.0 24.3 3.9e-31 108.3 21.5 2.0 1 1 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 OAG36932.1 - 0.0017 17.8 0.8 0.0017 17.8 0.8 2.0 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB TRI12 PF06609.13 OAG36933.1 - 2.3e-66 224.5 20.3 2.9e-66 224.1 20.3 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG36933.1 - 5e-20 71.7 54.1 7.4e-20 71.2 51.1 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily Arylesterase PF01731.20 OAG36934.1 - 1.3e-07 31.7 0.0 5e-07 29.8 0.0 2.1 2 0 0 2 2 2 1 Arylesterase SGL PF08450.12 OAG36934.1 - 0.0046 16.6 0.0 0.0078 15.8 0.0 1.3 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Lactonase PF10282.9 OAG36934.1 - 0.062 12.6 0.2 0.19 11.0 0.2 1.6 1 1 0 1 1 1 0 Lactonase, 7-bladed beta-propeller ADH_N PF08240.12 OAG36935.1 - 1.9e-22 79.2 0.6 4.7e-22 77.9 0.3 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG36935.1 - 8e-19 67.9 3.8 1.5e-18 67.0 1.4 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAG36935.1 - 3.9e-05 24.7 0.1 6.2e-05 24.1 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 OAG36935.1 - 0.019 14.3 0.2 0.036 13.3 0.2 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain CPSase_sm_chain PF00988.22 OAG36935.1 - 0.025 14.4 0.0 0.049 13.5 0.0 1.5 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase small chain, CPSase domain DUF3425 PF11905.8 OAG36936.1 - 4e-06 26.8 1.6 3.2e-05 23.9 0.1 3.0 3 1 0 3 3 3 1 Domain of unknown function (DUF3425) Abhydrolase_1 PF00561.20 OAG36937.1 - 3.7e-19 69.4 0.1 1.3e-18 67.5 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG36937.1 - 3.8e-14 53.8 0.0 5.3e-14 53.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG36937.1 - 1.2e-09 37.8 0.0 2.1e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 SnoaL_4 PF13577.6 OAG36938.1 - 9.5e-15 54.9 0.0 4e-14 52.8 0.0 1.8 2 0 0 2 2 2 1 SnoaL-like domain Ring_hydroxyl_B PF00866.18 OAG36938.1 - 0.025 14.6 0.1 0.09 12.9 0.0 1.8 2 0 0 2 2 2 0 Ring hydroxylating beta subunit FMO-like PF00743.19 OAG36939.1 - 2.5e-20 72.4 1.4 2.9e-18 65.6 1.4 3.3 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 OAG36939.1 - 3.8e-12 46.1 0.0 9.5e-10 38.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG36939.1 - 1.1e-11 44.6 0.0 8.8e-11 41.6 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG36939.1 - 6.3e-11 42.0 0.2 1.7e-07 30.7 0.0 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 OAG36939.1 - 3e-08 33.7 2.0 3.3e-08 33.6 0.0 2.2 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAG36939.1 - 1.7e-05 24.6 0.0 9.4e-05 22.1 0.0 2.3 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 OAG36939.1 - 0.00011 22.2 0.0 0.00058 19.9 0.0 2.3 3 0 0 3 3 3 1 FAD-NAD(P)-binding Shikimate_DH PF01488.20 OAG36939.1 - 0.0036 17.4 0.0 0.32 11.1 0.0 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.17 OAG36939.1 - 0.012 14.8 0.0 0.038 13.2 0.0 1.8 1 0 0 1 1 1 0 Thi4 family Amino_oxidase PF01593.24 OAG36939.1 - 0.032 13.5 0.0 0.12 11.6 0.0 1.8 1 1 1 2 2 2 0 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 OAG36939.1 - 0.05 14.2 0.0 2.3 8.8 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 OAG36939.1 - 0.051 12.8 0.1 8.9 5.4 0.0 2.8 3 0 0 3 3 3 0 FAD binding domain AlaDh_PNT_C PF01262.21 OAG36939.1 - 0.17 11.2 0.1 0.38 10.0 0.1 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ECH_1 PF00378.20 OAG36940.1 - 1.7e-41 142.2 0.0 3e-41 141.4 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAG36940.1 - 4.9e-24 85.4 0.1 4e-22 79.2 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase T6SS_VasE PF05936.12 OAG36940.1 - 0.13 10.9 0.2 0.31 9.7 0.1 1.6 2 0 0 2 2 2 0 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE ACOX PF01756.19 OAG36941.1 - 3.8e-16 59.2 0.1 6.4e-16 58.4 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 OAG36941.1 - 1.7e-13 51.2 0.2 4.6e-13 49.8 0.2 1.8 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 OAG36941.1 - 3.8e-05 23.8 0.0 0.00014 22.0 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain adh_short PF00106.25 OAG36942.1 - 3.6e-30 104.9 0.0 8.6e-30 103.6 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG36942.1 - 3.2e-23 82.5 0.2 1.1e-22 80.7 0.2 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG36942.1 - 0.18 11.7 1.5 1.5 8.7 0.6 2.3 2 1 0 2 2 2 0 KR domain Pyr_redox_3 PF13738.6 OAG36943.1 - 1e-11 44.6 0.1 1.7e-09 37.4 0.0 3.4 3 1 1 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 OAG36943.1 - 2.3e-10 39.5 0.1 3.2e-08 32.5 0.1 2.9 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 OAG36943.1 - 2.3e-08 33.6 0.0 5.2e-05 22.6 0.0 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG36943.1 - 2.5e-08 34.0 0.1 2.4e-07 30.9 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 OAG36943.1 - 0.00011 22.3 0.1 0.049 13.6 0.1 3.0 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.24 OAG36943.1 - 0.00019 21.2 0.7 0.031 13.9 0.8 2.8 3 0 0 3 3 3 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 OAG36943.1 - 0.00056 19.2 0.0 0.75 8.9 0.0 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Shikimate_DH PF01488.20 OAG36943.1 - 0.0014 18.7 0.2 0.2 11.7 0.0 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 OAG36943.1 - 0.0079 15.6 0.0 0.017 14.5 0.0 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ThiF PF00899.21 OAG36943.1 - 0.047 13.1 0.4 4.8 6.5 0.0 2.3 2 0 0 2 2 2 0 ThiF family NAD_binding_2 PF03446.15 OAG36943.1 - 0.068 13.3 0.5 2.5 8.2 0.0 2.6 3 0 0 3 3 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase FAD_binding_2 PF00890.24 OAG36943.1 - 0.075 12.1 0.3 0.12 11.4 0.3 1.3 1 0 0 1 1 1 0 FAD binding domain F420_oxidored PF03807.17 OAG36943.1 - 0.11 13.1 1.2 7.6 7.2 1.1 2.8 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent DUF3283 PF11686.8 OAG36943.1 - 0.11 12.3 0.1 0.36 10.7 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3283) Pyr_redox PF00070.27 OAG36943.1 - 0.38 11.4 3.3 14 6.3 1.8 3.0 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Blt1_C PF17183.4 OAG36944.1 - 0.085 12.5 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Get5 carboxyl domain NmrA PF05368.13 OAG36945.1 - 1.3e-05 24.9 0.0 3.2e-05 23.6 0.0 1.6 1 1 0 1 1 1 1 NmrA-like family PglL_A PF15864.5 OAG36945.1 - 0.069 12.9 4.5 0.9 9.3 0.3 2.5 2 0 0 2 2 2 0 Protein glycosylation ligase MFS_1 PF07690.16 OAG36946.1 - 5.3e-36 124.3 30.2 7.6e-36 123.8 30.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 OAG36946.1 - 0.00017 21.0 7.3 0.00017 21.0 7.3 2.0 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB PRK PF00485.18 OAG36947.1 - 0.01 15.6 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Zeta_toxin PF06414.12 OAG36947.1 - 0.012 14.9 0.0 0.021 14.1 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin KAP_NTPase PF07693.14 OAG36947.1 - 0.015 14.6 0.0 0.045 13.0 0.0 1.7 1 1 1 2 2 2 0 KAP family P-loop domain AAA_18 PF13238.6 OAG36947.1 - 0.051 14.1 0.0 0.091 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 OAG36947.1 - 0.15 11.2 0.0 2 7.5 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain adh_short PF00106.25 OAG36948.1 - 1.4e-85 285.7 10.6 2.6e-48 164.1 0.8 3.1 3 1 0 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAG36948.1 - 6.8e-64 215.6 5.0 3.2e-35 121.8 0.1 2.7 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase MaoC_dehydratas PF01575.19 OAG36948.1 - 4.8e-31 106.9 0.0 1.3e-30 105.5 0.0 1.7 2 0 0 2 2 2 1 MaoC like domain KR PF08659.10 OAG36948.1 - 7.8e-28 97.6 2.8 8.6e-15 55.1 0.2 2.4 2 0 0 2 2 2 2 KR domain Epimerase PF01370.21 OAG36948.1 - 0.0025 17.3 4.2 0.0037 16.8 0.2 2.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 OAG36948.1 - 0.02 14.2 0.6 0.27 10.5 0.1 2.3 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain MaoC_dehydrat_N PF13452.6 OAG36948.1 - 0.04 14.0 0.0 4.6 7.4 0.0 2.5 2 0 0 2 2 2 0 N-terminal half of MaoC dehydratase Glucodextran_B PF09136.10 OAG36948.1 - 0.061 13.7 0.1 0.25 11.8 0.1 2.1 1 0 0 1 1 1 0 Glucodextranase, domain B NAD_binding_7 PF13241.6 OAG36948.1 - 0.34 11.4 1.4 18 5.8 0.1 2.9 2 0 0 2 2 2 0 Putative NAD(P)-binding 3HCDH_N PF02737.18 OAG36948.1 - 7.1 6.5 6.6 13 5.6 1.5 2.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain IBR PF01485.21 OAG36949.1 - 1.9e-05 24.8 4.3 1.9e-05 24.8 4.3 4.6 4 1 1 5 5 5 4 IBR domain, a half RING-finger domain zinc_ribbon_9 PF14369.6 OAG36949.1 - 0.56 10.5 0.0 0.56 10.5 0.0 4.3 5 0 0 5 5 5 0 zinc-ribbon Aldo_ket_red PF00248.21 OAG36950.1 - 7.5e-59 199.3 0.0 1e-58 198.9 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Bclx_interact PF08945.10 OAG36950.1 - 0.15 11.9 0.2 0.33 10.8 0.2 1.5 1 0 0 1 1 1 0 Bcl-x interacting, BH3 domain Pam16 PF03656.13 OAG36951.1 - 1.4e-32 112.4 0.7 1.7e-32 112.1 0.7 1.0 1 0 0 1 1 1 1 Pam16 Pex24p PF06398.11 OAG36952.1 - 2.1e-92 309.9 0.0 2.9e-92 309.5 0.0 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Tmemb_cc2 PF10267.9 OAG36952.1 - 0.27 10.3 4.1 10 5.2 2.2 2.1 2 0 0 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein Lipase_3 PF01764.25 OAG36953.1 - 3.7e-05 23.6 0.0 7.4e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 OAG36953.1 - 0.0074 16.9 0.5 0.03 14.9 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG36953.1 - 0.06 12.6 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 VPS9 PF02204.18 OAG36954.1 - 2.4e-25 88.7 0.0 4.7e-25 87.8 0.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 OAG36954.1 - 0.011 16.1 0.9 0.076 13.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5601) RcsF PF16358.5 OAG36954.1 - 0.035 14.2 0.0 0.15 12.1 0.0 2.1 2 0 0 2 2 2 0 RcsF lipoprotein SlyX PF04102.12 OAG36954.1 - 0.055 14.1 0.1 1.4 9.6 0.0 3.5 3 0 0 3 3 3 0 SlyX ECM11 PF15463.6 OAG36955.1 - 7.8e-27 94.5 0.5 7.8e-27 94.5 0.5 2.6 3 1 0 3 3 3 1 Extracellular mutant protein 11 SPATA9 PF15824.5 OAG36955.1 - 0.16 11.2 0.9 0.34 10.2 0.9 1.4 1 0 0 1 1 1 0 Spermatogenesis-associated protein 9 Endomucin PF07010.12 OAG36955.1 - 6.9 6.6 8.7 0.14 12.1 0.9 2.1 2 0 0 2 2 2 0 Endomucin PAS_3 PF08447.12 OAG36956.1 - 3.7e-16 59.2 0.0 5.2e-12 45.9 0.0 2.3 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 OAG36956.1 - 2.2e-06 27.9 0.0 0.0012 19.1 0.0 2.4 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.10 OAG36956.1 - 1.3e-05 25.4 0.0 0.0046 17.2 0.0 2.7 2 0 0 2 2 2 2 PAS fold PAS PF00989.25 OAG36956.1 - 1.4e-05 25.1 0.0 0.0053 16.8 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.6 OAG36956.1 - 0.00013 22.1 0.0 0.0053 16.9 0.0 2.2 2 0 0 2 2 2 1 PAS domain Bac_luciferase PF00296.20 OAG36957.1 - 2.6e-54 184.8 0.0 5.1e-54 183.8 0.0 1.4 1 1 0 1 1 1 1 Luciferase-like monooxygenase Methyltrn_RNA_3 PF02598.17 OAG36957.1 - 0.07 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methyltransferase ADH_N PF08240.12 OAG36958.1 - 0.18 11.7 0.0 0.31 10.9 0.0 1.3 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain FMO-like PF00743.19 OAG36959.1 - 7.6e-15 54.3 0.0 2.3e-14 52.7 0.0 1.7 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OAG36959.1 - 5.5e-09 35.7 0.0 3.7e-08 33.0 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG36959.1 - 1.2e-08 35.0 0.0 4.4e-08 33.2 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAG36959.1 - 6.8e-08 32.1 0.0 1.5e-06 27.7 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG36959.1 - 2e-06 27.2 0.1 4.7e-05 22.7 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 OAG36959.1 - 0.00028 20.6 4.6 0.017 14.8 4.6 2.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 OAG36959.1 - 0.0041 16.4 0.1 0.01 15.1 0.1 1.6 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 OAG36959.1 - 0.0074 16.3 0.2 1.6 8.7 0.0 3.3 3 0 0 3 3 3 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 OAG36959.1 - 0.073 12.1 0.4 14 4.6 0.0 2.3 1 1 1 2 2 2 0 FAD binding domain Mqo PF06039.15 OAG36959.1 - 0.13 10.8 0.5 6 5.3 0.0 2.1 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) MFS_1 PF07690.16 OAG36960.1 - 4.2e-29 101.6 33.7 5.4e-29 101.2 33.3 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF5463 PF17551.2 OAG36960.1 - 0.15 12.0 1.2 0.43 10.6 1.2 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5463) Trep_Strep PF09605.10 OAG36960.1 - 2.8 7.9 18.1 0.61 10.0 0.9 3.5 3 0 0 3 3 3 0 Hypothetical bacterial integral membrane protein (Trep_Strep) Bac_luciferase PF00296.20 OAG36961.1 - 5.7e-57 193.5 0.0 8.2e-57 193.0 0.0 1.2 1 0 0 1 1 1 1 Luciferase-like monooxygenase MFS_1 PF07690.16 OAG36962.1 - 2.8e-29 102.1 22.7 2.8e-29 102.1 22.7 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Spectrin_like PF18373.1 OAG36962.1 - 0.19 11.8 0.1 1.7 8.8 0.0 2.3 2 0 0 2 2 2 0 Spectrin like domain BPL_N PF09825.9 OAG36963.1 - 1e-142 475.7 0.0 4.8e-142 473.5 0.0 1.8 2 0 0 2 2 2 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.19 OAG36963.1 - 2.6e-21 75.9 0.0 5.6e-21 74.8 0.0 1.5 2 0 0 2 2 2 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.17 OAG36963.1 - 9.3e-05 22.2 0.0 0.00019 21.3 0.0 1.6 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain Mgm101p PF06420.12 OAG36964.1 - 1.1e-85 285.4 0.0 1.4e-85 285.0 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 CHCH PF06747.13 OAG36964.1 - 8.7 6.6 8.1 0.32 11.2 2.2 1.7 2 0 0 2 2 2 0 CHCH domain Usp PF00582.26 OAG36965.1 - 3.9e-21 76.0 0.0 1.2e-20 74.5 0.0 1.9 1 0 0 1 1 1 1 Universal stress protein family HEPPP_synt_1 PF07307.11 OAG36965.1 - 0.0056 16.3 0.0 0.0095 15.6 0.0 1.2 1 0 0 1 1 1 1 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 ABA_GPCR PF12430.8 OAG36966.1 - 4.2e-52 176.5 2.1 4.2e-52 176.5 2.1 2.2 2 0 0 2 2 2 1 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 OAG36966.1 - 1.2e-21 76.5 0.0 1.2e-21 76.5 0.0 2.8 4 0 0 4 4 4 1 The Golgi pH Regulator (GPHR) Family N-terminal MitoNEET_N PF10660.9 OAG36966.1 - 0.012 15.6 0.1 0.046 13.8 0.1 2.1 1 0 0 1 1 1 0 Iron-containing outer mitochondrial membrane protein N-terminus Syntaxin-18_N PF10496.9 OAG36967.1 - 1.1e-07 32.0 0.0 5.4e-07 29.8 0.0 2.2 2 0 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.19 OAG36967.1 - 2.2e-06 27.6 0.2 5.3e-06 26.3 0.0 1.8 2 0 0 2 2 2 1 SNARE domain DUF5089 PF17002.5 OAG36967.1 - 0.021 14.7 0.5 2.1 8.2 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF5089) RepB-RCR_reg PF10723.9 OAG36967.1 - 0.12 12.4 0.1 0.39 10.7 0.1 1.8 1 0 0 1 1 1 0 Replication regulatory protein RepB DUF3332 PF11810.8 OAG36967.1 - 0.16 11.6 0.1 0.39 10.3 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3332) Aminotran_1_2 PF00155.21 OAG36968.1 - 1.7e-82 277.5 0.0 1.9e-82 277.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Acetyltransf_1 PF00583.25 OAG36969.1 - 0.06 13.6 0.0 0.099 12.9 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OAG36969.1 - 0.072 13.0 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OAG36969.1 - 0.19 12.2 0.0 0.38 11.2 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain TP2 PF01254.18 OAG36969.1 - 0.85 10.2 7.9 1.4 9.5 7.9 1.3 1 0 0 1 1 1 0 Nuclear transition protein 2 MS_channel PF00924.18 OAG36971.1 - 7.3e-21 74.7 0.6 1.3e-20 73.9 0.6 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.32 OAG36971.1 - 0.0031 17.0 0.2 0.0088 15.5 0.2 1.9 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 OAG36971.1 - 0.032 14.7 0.2 0.097 13.1 0.2 1.8 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_6 PF13405.6 OAG36971.1 - 0.037 14.0 0.3 0.22 11.5 0.1 2.5 3 0 0 3 3 3 0 EF-hand domain MFS_1 PF07690.16 OAG36973.1 - 1.6e-35 122.7 34.6 1.7e-25 89.7 13.2 3.0 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG36973.1 - 1.2e-15 57.4 3.3 1.2e-15 57.4 3.3 2.8 3 0 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 OAG36973.1 - 0.0015 17.1 3.4 0.0026 16.2 3.4 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Med12 PF09497.10 OAG36974.1 - 1.9e-26 92.1 0.2 4.6e-26 90.9 0.2 1.7 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 Zn_clus PF00172.18 OAG36975.1 - 3.5e-08 33.4 10.2 6e-08 32.7 10.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 OAG36975.1 - 3.4e-06 26.1 1.5 8.3e-06 24.9 1.4 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain RTA1 PF04479.13 OAG36976.1 - 1.1e-71 240.8 3.8 1.5e-71 240.3 3.8 1.2 1 0 0 1 1 1 1 RTA1 like protein DUF4131 PF13567.6 OAG36976.1 - 7.1 6.3 11.1 4.9 6.8 3.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) GST_N_3 PF13417.6 OAG36977.1 - 8.4e-15 54.9 0.0 1.5e-14 54.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 OAG36977.1 - 7.3e-14 51.9 0.0 2.2e-13 50.3 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OAG36977.1 - 4.5e-11 42.9 0.0 1.1e-10 41.7 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OAG36977.1 - 1.4e-08 34.8 0.0 2.4e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OAG36977.1 - 7e-06 26.2 0.0 1.8e-05 24.9 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OAG36977.1 - 7.9e-06 25.8 0.1 1.4e-05 25.0 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Coatomer_WDAD PF04053.14 OAG36978.1 - 9e-166 552.3 0.0 2.4e-165 550.9 0.0 1.7 2 1 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.32 OAG36978.1 - 4.5e-30 103.3 1.1 9.5e-06 26.3 0.0 7.0 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG36978.1 - 1.5e-06 28.4 0.1 2.1 8.7 0.1 4.6 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OAG36978.1 - 7.6e-05 21.5 0.9 0.066 11.8 0.6 2.7 1 1 1 2 2 2 1 Nucleoporin Nup120/160 Guanylate_cyc PF00211.20 OAG36979.1 - 3e-22 79.1 0.0 9.6e-21 74.2 0.0 2.0 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain Aconitase PF00330.20 OAG36980.1 - 1.8e-163 544.8 0.0 2.2e-163 544.6 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 OAG36980.1 - 5e-41 140.1 0.0 1e-40 139.1 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF3394 PF11874.8 OAG36980.1 - 0.03 14.0 0.1 5.6 6.6 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3394) Aconitase_2_N PF06434.13 OAG36980.1 - 0.11 12.1 0.0 0.9 9.1 0.0 2.4 1 1 0 1 1 1 0 Aconitate hydratase 2 N-terminus RGS PF00615.19 OAG36981.1 - 3.2e-29 101.6 0.1 1.2e-28 99.8 0.1 1.9 2 0 0 2 2 2 1 Regulator of G protein signaling domain DEP PF00610.21 OAG36981.1 - 4.8e-22 77.8 0.0 1.2e-17 63.7 0.0 3.3 3 0 0 3 3 3 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Mrr_N PF14338.6 OAG36981.1 - 0.016 15.3 0.1 27 5.0 0.0 3.6 3 0 0 3 3 3 0 Mrr N-terminal domain TDRP PF15683.5 OAG36981.1 - 0.57 10.1 5.5 7.4 6.5 3.3 2.6 2 0 0 2 2 2 0 Testis development-related protein CDC73_C PF05179.14 OAG36982.1 - 1.1e-55 187.6 0.0 2.1e-55 186.7 0.0 1.4 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal OsmC PF02566.19 OAG36984.1 - 4.3e-16 59.2 0.0 6.8e-16 58.6 0.0 1.3 1 0 0 1 1 1 1 OsmC-like protein MFS_1 PF07690.16 OAG36985.1 - 3.3e-15 55.9 66.1 1.3e-14 53.9 57.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ESPR PF13018.6 OAG36985.1 - 0.14 12.0 0.1 0.28 11.0 0.1 1.5 1 0 0 1 1 1 0 Extended Signal Peptide of Type V secretion system G-alpha PF00503.20 OAG36986.1 - 9.3e-39 133.6 0.4 1.8e-38 132.6 0.4 1.4 1 0 0 1 1 1 1 G-protein alpha subunit Helo_like_N PF17111.5 OAG36986.1 - 0.022 14.2 0.6 0.047 13.1 0.6 1.7 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins Glutaredoxin PF00462.24 OAG36987.1 - 1.9e-17 63.2 0.0 1.4e-15 57.2 0.0 2.5 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.20 OAG36987.1 - 4.2e-12 45.9 0.0 1.9e-11 43.8 0.0 2.0 2 1 0 2 2 2 1 Thioredoxin Thioredoxin_8 PF13905.6 OAG36987.1 - 0.052 13.9 0.0 1.3 9.4 0.0 2.4 1 1 1 2 2 2 0 Thioredoxin-like TauD PF02668.16 OAG36988.1 - 6.4e-43 147.5 0.2 9.2e-43 147.0 0.2 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 OAG36988.1 - 0.0022 18.6 0.0 0.0061 17.2 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF971) WD40 PF00400.32 OAG36989.1 - 8.8e-14 51.7 3.9 0.12 13.3 0.2 6.6 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG36989.1 - 0.016 15.5 0.1 2.9 8.3 0.0 3.5 4 2 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain CENP-K PF11802.8 OAG36990.1 - 0.84 9.2 6.2 1 8.9 0.9 2.1 2 0 0 2 2 2 0 Centromere-associated protein K DUF1484 PF07363.11 OAG36990.1 - 1.2 10.2 3.2 0.63 11.1 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1484) LSM PF01423.22 OAG36991.1 - 8.5e-20 70.2 0.7 1.4e-19 69.5 0.7 1.4 1 0 0 1 1 1 1 LSM domain Acetyltransf_3 PF13302.7 OAG36991.1 - 2.1e-13 51.1 0.0 3.9e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAG36991.1 - 0.081 13.2 0.0 0.3 11.3 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family Peptidase_M1_N PF17900.1 OAG36992.1 - 7.3e-05 23.0 0.0 0.062 13.5 0.0 2.6 2 0 0 2 2 2 2 Peptidase M1 N-terminal domain Ntox28 PF15605.6 OAG36992.1 - 0.043 14.1 0.9 1.1 9.5 0.1 2.5 2 0 0 2 2 2 0 Bacterial toxin 28 CDP-OH_P_transf PF01066.21 OAG36993.1 - 4.3e-07 30.6 0.3 4.3e-07 30.6 0.3 3.3 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase ECF_trnsprt PF12822.7 OAG36993.1 - 0.25 11.4 7.1 0.48 10.5 7.1 1.5 1 1 0 1 1 1 0 ECF transporter, substrate-specific component HpcH_HpaI PF03328.14 OAG36994.1 - 2.8e-42 144.4 0.0 3.8e-42 143.9 0.0 1.2 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 OAG36994.1 - 1.6e-13 50.5 0.1 1.3e-08 34.3 0.0 2.2 1 1 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold DUF2293 PF10056.9 OAG36996.1 - 4.9e-29 100.4 0.1 1.7e-28 98.7 0.1 2.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2293) Hydrolase_4 PF12146.8 OAG36997.1 - 1.7e-24 86.4 0.0 1.2e-23 83.6 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OAG36997.1 - 2.9e-19 69.7 0.2 1.5e-17 64.1 0.2 2.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG36997.1 - 6.2e-16 59.7 0.0 7.4e-16 59.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.13 OAG36997.1 - 2.1e-06 27.7 0.1 0.0001 22.2 0.1 2.5 1 1 0 1 1 1 1 Serine hydrolase Thioesterase PF00975.20 OAG36997.1 - 3.3e-06 27.4 0.0 0.00031 20.9 0.0 2.4 2 1 0 2 2 2 1 Thioesterase domain Esterase PF00756.20 OAG36997.1 - 0.00023 20.9 0.1 0.0012 18.5 0.0 2.0 2 0 0 2 2 2 1 Putative esterase PGAP1 PF07819.13 OAG36997.1 - 0.00053 19.8 0.0 0.0011 18.7 0.0 1.7 2 0 0 2 2 2 1 PGAP1-like protein Abhydrolase_5 PF12695.7 OAG36997.1 - 0.0011 18.8 0.0 0.0044 16.8 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family LIDHydrolase PF10230.9 OAG36997.1 - 0.0014 18.2 0.0 0.0039 16.8 0.0 1.5 1 1 0 2 2 2 1 Lipid-droplet associated hydrolase Abhydrolase_2 PF02230.16 OAG36997.1 - 0.0018 18.1 0.0 0.19 11.5 0.0 2.2 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase FSH1 PF03959.13 OAG36997.1 - 0.0093 15.6 0.1 0.03 14.0 0.0 1.9 3 0 0 3 3 3 1 Serine hydrolase (FSH1) DUF915 PF06028.11 OAG36997.1 - 0.06 12.7 0.1 2.3 7.5 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_3 PF07859.13 OAG36997.1 - 0.11 12.4 0.0 0.16 11.8 0.0 1.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold DUF676 PF05057.14 OAG36997.1 - 0.13 11.7 0.1 0.94 8.9 0.1 2.1 2 0 0 2 2 2 0 Putative serine esterase (DUF676) LCAT PF02450.15 OAG36997.1 - 0.17 11.0 0.0 0.26 10.4 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase TauD PF02668.16 OAG36998.1 - 6.5e-34 117.9 0.1 8.7e-34 117.5 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Zn_clus PF00172.18 OAG36999.1 - 7e-08 32.5 11.8 1.4e-07 31.5 11.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cep3 PF16846.5 OAG36999.1 - 0.00011 20.8 0.0 0.00017 20.2 0.0 1.2 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit B Fungal_trans PF04082.18 OAG36999.1 - 0.031 13.3 1.5 0.054 12.5 0.2 2.0 2 1 1 3 3 3 0 Fungal specific transcription factor domain TauD PF02668.16 OAG37000.1 - 8.5e-35 120.8 0.1 1.2e-34 120.3 0.1 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DIOX_N PF14226.6 OAG37001.1 - 7.1e-30 104.2 0.0 1.1e-29 103.6 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OAG37001.1 - 1.2e-19 70.7 0.1 2.2e-19 69.8 0.1 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Transp_cyt_pur PF02133.15 OAG37002.1 - 3.7e-74 250.1 35.2 4.6e-74 249.8 35.2 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin LZ3wCH PF18517.1 OAG37003.1 - 0.17 12.0 0.7 0.27 11.4 0.7 1.4 1 0 0 1 1 1 0 Leucine zipper with capping helix domain Herpes_U5 PF05999.11 OAG37004.1 - 0.0092 14.8 0.4 0.011 14.6 0.4 1.1 1 0 0 1 1 1 1 Herpesvirus U5-like family Complex1_LYR PF05347.15 OAG37004.1 - 0.02 14.9 2.4 0.02 14.9 2.4 1.8 2 0 0 2 2 2 0 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 OAG37004.1 - 0.12 13.1 3.9 0.29 11.9 3.9 1.8 1 1 0 1 1 1 0 Complex1_LYR-like Latarcin PF10279.9 OAG37004.1 - 0.15 12.5 0.4 0.71 10.3 0.1 1.9 1 1 1 2 2 2 0 Latarcin precursor MFS_1 PF07690.16 OAG37005.1 - 2.4e-41 141.9 45.7 2.4e-41 141.9 45.7 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG37005.1 - 1e-09 37.8 7.2 1e-09 37.8 7.2 2.4 3 0 0 3 3 3 1 Sugar (and other) transporter AtuA PF07287.11 OAG37006.1 - 8.5e-132 439.1 0.0 1e-131 438.9 0.0 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA CoA_transf_3 PF02515.17 OAG37007.1 - 5.2e-40 137.7 0.0 9.2e-37 127.0 0.0 2.1 2 0 0 2 2 2 2 CoA-transferase family III Cytochrom_B562 PF07361.11 OAG37007.1 - 0.071 13.8 0.0 0.18 12.5 0.0 1.8 2 0 0 2 2 2 0 Cytochrome b562 HSP20 PF00011.21 OAG37009.1 - 3.7e-20 72.0 0.7 1.3e-14 54.2 0.1 2.1 1 1 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 OAG37009.1 - 1.3e-05 24.6 0.2 6.6e-05 22.4 0.2 1.9 1 1 0 1 1 1 1 HSP20-like domain found in ArsA HSP20 PF00011.21 OAG37011.1 - 3.3e-10 40.0 0.0 6.6e-08 32.6 0.0 2.2 2 0 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 OAG37011.1 - 0.00032 20.2 0.0 0.0052 16.3 0.0 2.2 2 0 0 2 2 2 1 HSP20-like domain found in ArsA HLH PF00010.26 OAG37012.1 - 3e-09 36.7 0.0 7.8e-09 35.4 0.0 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Nop14 PF04147.12 OAG37014.1 - 0.04 12.2 6.1 0.049 11.8 6.1 1.1 1 0 0 1 1 1 0 Nop14-like family Ion_trans PF00520.31 OAG37016.1 - 5.5e-10 38.9 2.3 7.1e-10 38.5 2.3 1.1 1 0 0 1 1 1 1 Ion transport protein CCDC85 PF10226.9 OAG37016.1 - 0.0032 17.2 0.6 0.0054 16.4 0.6 1.3 1 0 0 1 1 1 1 CCDC85 family DUF5082 PF16888.5 OAG37016.1 - 0.0059 16.9 0.5 0.01 16.1 0.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5082) ZapB PF06005.12 OAG37016.1 - 0.024 15.1 1.6 0.04 14.4 1.6 1.3 1 0 0 1 1 1 0 Cell division protein ZapB Med21 PF11221.8 OAG37016.1 - 0.054 13.8 1.5 0.088 13.1 1.5 1.3 1 0 0 1 1 1 0 Subunit 21 of Mediator complex TSC22 PF01166.18 OAG37016.1 - 0.072 13.4 1.6 0.13 12.6 1.6 1.3 1 0 0 1 1 1 0 TSC-22/dip/bun family DivIC PF04977.15 OAG37016.1 - 0.14 11.9 1.2 0.31 10.8 1.2 1.5 1 0 0 1 1 1 0 Septum formation initiator HpcH_HpaI PF03328.14 OAG37017.1 - 8.4e-31 106.8 0.0 1.2e-30 106.3 0.0 1.2 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PK PF00224.21 OAG37017.1 - 0.017 14.0 0.1 0.025 13.5 0.1 1.2 1 0 0 1 1 1 0 Pyruvate kinase, barrel domain Amidase PF01425.21 OAG37018.1 - 1.1e-40 140.0 0.0 1.6e-39 136.2 0.0 2.0 1 1 0 1 1 1 1 Amidase CWC25 PF12542.8 OAG37019.1 - 4e-27 95.1 1.3 4e-27 95.1 1.3 3.1 2 1 1 3 3 3 1 Pre-mRNA splicing factor Cir_N PF10197.9 OAG37019.1 - 1.5e-14 53.9 10.0 1.5e-14 53.9 10.0 2.9 3 0 0 3 3 3 1 N-terminal domain of CBF1 interacting co-repressor CIR PCI PF01399.27 OAG37020.1 - 1.2e-21 77.2 2.2 1.5e-21 76.9 0.7 2.0 2 0 0 2 2 2 1 PCI domain TPR_12 PF13424.6 OAG37020.1 - 0.0021 18.3 0.6 0.97 9.8 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 OAG37020.1 - 0.0073 16.3 0.7 0.84 9.8 0.0 3.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 OAG37020.1 - 0.035 14.2 4.8 0.27 11.5 0.1 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat HTH_9 PF08221.11 OAG37020.1 - 0.071 13.2 0.1 0.15 12.2 0.1 1.5 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 helix-turn-helix domain TPR_11 PF13414.6 OAG37020.1 - 0.2 11.4 0.1 0.2 11.4 0.1 2.5 3 0 0 3 3 3 0 TPR repeat TPR_1 PF00515.28 OAG37020.1 - 0.73 9.7 5.4 1.1 9.3 0.2 3.8 4 1 1 5 5 5 0 Tetratricopeptide repeat RPN6_N PF18055.1 OAG37020.1 - 0.8 10.1 3.9 22 5.4 0.8 3.2 3 0 0 3 3 3 0 26S proteasome regulatory subunit RPN6 N-terminal domain TPR_14 PF13428.6 OAG37020.1 - 0.85 10.6 2.4 1.8 9.6 0.0 2.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Peptidase_C65 PF10275.9 OAG37021.1 - 1.3e-60 204.9 0.0 1.9e-60 204.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase C65 Otubain GnsAB_toxin PF08178.11 OAG37021.1 - 0.16 11.9 0.0 0.32 11.0 0.0 1.4 1 0 0 1 1 1 0 GnsA/GnsB toxin of bacterial toxin-antitoxin system BPL_LplA_LipB PF03099.19 OAG37022.1 - 0.0045 16.9 0.0 0.0097 15.8 0.0 1.5 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Tmemb_40 PF10160.9 OAG37023.1 - 0.083 12.3 1.3 1.9 7.8 0.1 2.4 2 0 0 2 2 2 0 Predicted membrane protein COX17 PF05051.13 OAG37024.1 - 0.0054 17.1 0.2 0.13 12.6 0.0 2.1 2 0 0 2 2 2 1 Cytochrome C oxidase copper chaperone (COX17) Pet191_N PF10203.9 OAG37024.1 - 0.041 14.2 2.4 1.9 8.9 1.4 2.0 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 CHCH PF06747.13 OAG37024.1 - 0.073 13.2 0.1 0.11 12.6 0.1 1.3 1 0 0 1 1 1 0 CHCH domain GDH_N PF12466.8 OAG37024.1 - 0.086 13.1 0.0 0.11 12.8 0.0 1.1 1 0 0 1 1 1 0 Glutamate dehydrogenase N terminal Ribonuc_P_40 PF08584.11 OAG37025.1 - 3.3e-53 180.8 0.0 4.3e-53 180.4 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit MFS_1 PF07690.16 OAG37026.1 - 2.4e-27 95.8 25.3 2.4e-27 95.8 25.3 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily TMEM100 PF16311.5 OAG37026.1 - 1.6 8.3 5.3 2 8.0 0.4 2.9 3 0 0 3 3 3 0 Transmembrane protein 100 Fungal_trans_2 PF11951.8 OAG37027.1 - 3.9e-05 22.6 0.1 7.1e-05 21.8 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain CK_II_beta PF01214.18 OAG37028.1 - 2.8e-77 258.6 0.1 3.7e-77 258.2 0.1 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit CxC5 PF18718.1 OAG37028.1 - 0.13 12.4 0.2 0.41 10.7 0.0 1.9 2 0 0 2 2 2 0 CxC5 like cysteine cluster associated with KDZ transposases RXT2_N PF08595.11 OAG37029.1 - 3.5e-39 134.3 0.0 3.5e-39 134.3 0.0 3.2 3 1 0 3 3 3 1 RXT2-like, N-terminal PEMT PF04191.13 OAG37030.1 - 2.3e-33 114.7 1.9 7.6e-33 113.1 1.0 2.1 2 0 0 2 2 2 1 Phospholipid methyltransferase Gryzun PF07919.12 OAG37031.1 - 5.9e-171 570.2 0.0 7.3e-171 569.9 0.0 1.1 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi Foie-gras_1 PF11817.8 OAG37031.1 - 2.6e-75 253.4 0.2 2e-68 230.8 0.2 2.2 2 0 0 2 2 2 2 Foie gras liver health family 1 TPR_14 PF13428.6 OAG37032.1 - 3.5e-05 24.3 0.5 0.058 14.2 0.1 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 OAG37032.1 - 4.3e-05 23.7 1.9 0.0073 16.6 0.3 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 OAG37032.1 - 0.00037 20.9 0.1 0.03 14.8 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 OAG37032.1 - 0.0026 17.6 1.7 0.16 11.8 0.1 3.6 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_4 PF07721.14 OAG37032.1 - 0.0029 18.1 4.5 0.03 14.9 1.4 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 OAG37032.1 - 0.015 15.4 0.2 0.18 12.0 0.3 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 OAG37032.1 - 0.015 16.0 1.3 0.44 11.2 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_MalT PF17874.1 OAG37032.1 - 0.054 12.9 5.9 0.47 9.8 1.7 2.3 1 1 1 2 2 2 0 MalT-like TPR region TPR_7 PF13176.6 OAG37032.1 - 0.089 12.9 1.1 1.1 9.4 0.2 3.1 3 1 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 OAG37032.1 - 0.14 12.4 0.5 0.4 10.9 0.2 1.9 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 UAA PF08449.11 OAG37033.1 - 2.3e-45 155.1 11.9 2.8e-45 154.8 11.9 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 OAG37033.1 - 9.2e-09 35.6 26.3 6.7e-07 29.5 7.5 3.6 3 1 0 3 3 3 2 EamA-like transporter family Nuc_sug_transp PF04142.15 OAG37033.1 - 2.8e-06 26.7 1.4 0.042 13.0 0.2 2.2 2 0 0 2 2 2 2 Nucleotide-sugar transporter TPT PF03151.16 OAG37033.1 - 0.14 11.4 9.8 0.55 9.5 0.4 2.2 2 0 0 2 2 2 0 Triose-phosphate Transporter family DUF1604 PF07713.13 OAG37034.1 - 2.7e-41 139.3 3.2 2.7e-41 139.3 3.2 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1604) G-patch PF01585.23 OAG37034.1 - 4.2e-07 29.7 0.7 1.5e-06 28.0 0.2 2.1 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 OAG37034.1 - 0.0015 18.6 1.8 0.015 15.3 0.3 3.1 2 1 0 2 2 2 1 G-patch domain Pkinase PF00069.25 OAG37035.1 - 3e-70 236.6 0.0 4.4e-70 236.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG37035.1 - 2.4e-39 135.2 0.0 3.6e-39 134.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 OAG37035.1 - 7.6e-15 54.4 0.1 1.6e-14 53.4 0.1 1.6 1 0 0 1 1 1 1 Kinase associated domain 1 Kdo PF06293.14 OAG37035.1 - 6.9e-06 25.6 0.1 1.3e-05 24.7 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OAG37035.1 - 1.1e-05 24.6 0.0 1.7e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 OAG37035.1 - 1.7e-05 24.3 0.0 0.00012 21.5 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 OAG37035.1 - 0.0005 20.1 0.1 0.0078 16.2 0.0 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 OAG37035.1 - 0.15 11.6 0.0 0.32 10.5 0.0 1.5 1 0 0 1 1 1 0 RIO1 family LsmAD PF06741.13 OAG37036.1 - 1.5e-30 105.5 5.4 3.8e-30 104.3 5.4 1.7 1 0 0 1 1 1 1 LsmAD domain SM-ATX PF14438.6 OAG37036.1 - 1.5e-14 53.9 0.0 3.9e-14 52.6 0.0 1.8 1 0 0 1 1 1 1 Ataxin 2 SM domain 14-3-3 PF00244.20 OAG37037.1 - 1.1e-07 31.7 0.1 4.1e-07 29.7 0.0 1.8 2 0 0 2 2 2 1 14-3-3 protein Rad60-SLD PF11976.8 OAG37038.1 - 1e-19 70.1 0.1 1.2e-19 69.9 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 OAG37038.1 - 1.1e-10 41.1 0.1 1.3e-10 40.9 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin family SEP PF08059.13 OAG37038.1 - 0.028 15.0 0.1 1.3 9.6 0.0 2.1 2 0 0 2 2 2 0 SEP domain Tubulin PF00091.25 OAG37039.1 - 2.3e-67 227.0 0.0 5.5e-67 225.8 0.0 1.6 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 OAG37039.1 - 2.9e-43 147.0 0.1 4.8e-43 146.3 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 OAG37039.1 - 0.00053 20.3 0.0 0.21 11.9 0.0 2.5 2 0 0 2 2 2 2 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 OAG37039.1 - 0.00056 19.2 0.0 0.023 13.9 0.0 2.1 2 0 0 2 2 2 1 Tubulin like Tubulin_3 PF14881.6 OAG37039.1 - 0.0029 17.3 0.0 0.0055 16.4 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Aldedh PF00171.22 OAG37040.1 - 1.6e-110 369.8 0.0 1.9e-110 369.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Ligase_CoA PF00549.19 OAG37042.1 - 1.3e-32 112.7 1.8 2.9e-15 56.4 0.1 2.5 2 0 0 2 2 2 2 CoA-ligase CoA_binding PF02629.19 OAG37042.1 - 2.2e-17 63.5 0.1 6.7e-17 62.0 0.1 1.9 1 0 0 1 1 1 1 CoA binding domain Succ_CoA_lig PF13607.6 OAG37042.1 - 1.4e-08 34.6 0.5 3.3e-06 26.9 0.0 2.9 2 0 0 2 2 2 2 Succinyl-CoA ligase like flavodoxin domain ATP-grasp_2 PF08442.10 OAG37042.1 - 0.075 12.6 0.1 0.84 9.2 0.0 2.6 2 1 0 2 2 2 0 ATP-grasp domain Nup84_Nup100 PF04121.13 OAG37044.1 - 3.5e-126 422.2 6.1 3.5e-126 422.2 6.1 1.6 2 0 0 2 2 2 1 Nuclear pore protein 84 / 107 HHH_8 PF14716.6 OAG37044.1 - 0.027 14.8 0.2 0.082 13.3 0.2 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix domain XRCC4 PF06632.12 OAG37044.1 - 0.34 9.7 3.8 0.16 10.8 0.1 2.0 1 1 1 2 2 2 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 HD PF01966.22 OAG37045.1 - 0.00013 22.2 0.0 0.00051 20.3 0.0 2.0 1 1 0 1 1 1 1 HD domain Cation_ATPase_C PF00689.21 OAG37046.1 - 6.3e-47 159.6 8.1 6.3e-47 159.6 8.1 2.4 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 OAG37046.1 - 1.5e-36 125.6 0.4 1.5e-36 125.6 0.4 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 OAG37046.1 - 2.4e-22 78.8 0.0 4.5e-22 77.9 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 OAG37046.1 - 1.9e-18 67.5 1.9 1.1e-17 65.1 1.9 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase 4HBT PF03061.22 OAG37046.1 - 1.1e-09 38.5 0.0 2.8e-09 37.2 0.0 1.7 1 0 0 1 1 1 1 Thioesterase superfamily Cation_ATPase_N PF00690.26 OAG37046.1 - 1.9e-06 27.5 0.3 8.8e-06 25.3 0.1 2.2 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 OAG37046.1 - 5.9e-05 22.9 0.9 0.00011 22.0 0.6 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase LptF_LptG PF03739.14 OAG37046.1 - 0.029 13.2 5.0 0.044 12.6 3.5 2.0 2 0 0 2 2 2 0 Lipopolysaccharide export system permease LptF/LptG peroxidase PF00141.23 OAG37047.1 - 1.2e-85 286.8 0.0 6.3e-44 150.4 0.0 2.3 2 0 0 2 2 2 2 Peroxidase GST_C_3 PF14497.6 OAG37047.1 - 0.0029 17.8 0.0 1.5 9.0 0.0 2.5 2 0 0 2 2 2 2 Glutathione S-transferase, C-terminal domain V-ATPase_C PF03223.15 OAG37048.1 - 7.3e-122 407.3 0.1 8.3e-122 407.2 0.1 1.0 1 0 0 1 1 1 1 V-ATPase subunit C Mad3_BUB1_I PF08311.12 OAG37048.1 - 0.063 13.3 0.2 0.12 12.4 0.2 1.4 1 0 0 1 1 1 0 Mad3/BUB1 homology region 1 DUF4983 PF16356.5 OAG37048.1 - 0.15 12.9 0.0 0.32 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4983) PTPA PF03095.15 OAG37049.1 - 1.5e-110 369.4 0.0 1.8e-110 369.1 0.0 1.1 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Glyco_transf_8 PF01501.20 OAG37052.1 - 7.5e-11 42.1 0.0 7.3e-10 38.8 0.0 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mito_carr PF00153.27 OAG37053.1 - 6.6e-55 183.0 0.7 1.6e-18 66.4 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein RNase_PH PF01138.21 OAG37054.1 - 8.3e-10 39.3 0.0 1.6e-09 38.4 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 NAD_kinase PF01513.21 OAG37055.1 - 6.3e-79 265.2 0.0 8.5e-79 264.8 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase DEAD PF00270.29 OAG37057.1 - 4.8e-41 140.4 0.1 8.3e-41 139.7 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAG37057.1 - 4.6e-33 113.9 0.0 9e-33 112.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 OAG37057.1 - 0.014 15.1 0.2 0.023 14.4 0.2 1.4 1 1 0 1 1 1 0 AAA domain ResIII PF04851.15 OAG37057.1 - 0.031 14.3 0.0 0.058 13.4 0.0 1.5 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit TniB PF05621.11 OAG37057.1 - 0.091 12.2 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein p450 PF00067.22 OAG37058.1 - 3.9e-68 230.3 0.0 1.9e-67 228.0 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 adh_short PF00106.25 OAG37059.1 - 3.8e-47 160.3 2.4 4.2e-47 160.1 2.4 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG37059.1 - 1.9e-46 158.5 3.0 2.1e-46 158.4 3.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG37059.1 - 1.3e-12 48.0 1.0 2.1e-12 47.3 1.0 1.3 1 1 0 1 1 1 1 KR domain Peripla_BP_4 PF13407.6 OAG37059.1 - 0.00084 19.0 1.3 0.0011 18.6 1.3 1.3 1 0 0 1 1 1 1 Periplasmic binding protein domain Sacchrp_dh_NADP PF03435.18 OAG37059.1 - 0.0018 18.5 0.6 0.0038 17.5 0.6 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Ldh_1_N PF00056.23 OAG37059.1 - 0.0075 16.4 0.8 0.013 15.6 0.8 1.5 1 1 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain adh_short PF00106.25 OAG37060.1 - 1e-16 61.0 0.0 1.3e-16 60.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG37060.1 - 2.9e-12 46.7 0.0 3.7e-12 46.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG37060.1 - 8.6e-05 22.5 0.0 0.0001 22.2 0.0 1.1 1 0 0 1 1 1 1 KR domain Abhydrolase_1 PF00561.20 OAG37061.1 - 1.3e-19 70.9 0.3 2e-15 57.1 0.1 2.0 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG37061.1 - 5.6e-16 59.8 0.3 7.5e-16 59.4 0.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG37061.1 - 2.4e-07 30.3 0.0 1.1e-06 28.1 0.0 1.8 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 OAG37061.1 - 0.029 13.3 0.0 0.047 12.6 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme EHN PF06441.12 OAG37061.1 - 0.037 14.4 0.0 0.078 13.4 0.0 1.6 1 0 0 1 1 1 0 Epoxide hydrolase N terminus DUF1057 PF06342.12 OAG37061.1 - 0.098 11.7 0.0 0.14 11.2 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) adh_short PF00106.25 OAG37062.1 - 7.1e-35 120.2 0.0 1e-34 119.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG37062.1 - 4.1e-27 95.3 0.0 6.5e-27 94.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG37062.1 - 2.6e-06 27.5 0.0 5.2e-05 23.2 0.0 2.3 1 1 0 1 1 1 1 KR domain Lactamase_B_3 PF13483.6 OAG37062.1 - 0.0001 22.3 0.0 0.00022 21.2 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 OAG37062.1 - 0.022 14.2 0.0 0.046 13.2 0.0 1.5 1 0 0 1 1 1 0 Beta-lactamase superfamily domain LCE PF14672.6 OAG37062.1 - 6 7.5 9.8 1.6 9.4 5.8 2.1 2 0 0 2 2 2 0 Late cornified envelope DUF3818 PF12825.7 OAG37063.1 - 2.5e-53 181.3 4.8 4e-32 111.6 0.2 2.2 1 1 1 2 2 2 2 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 OAG37063.1 - 1.6e-31 109.0 0.0 3.8e-31 107.8 0.0 1.7 1 0 0 1 1 1 1 PX-associated Arrestin_C PF02752.22 OAG37064.1 - 3.5e-15 56.6 0.1 7.4e-15 55.6 0.1 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain WD40 PF00400.32 OAG37064.1 - 2.9e-11 43.7 10.8 0.00054 20.7 0.5 5.6 4 0 0 4 4 4 3 WD domain, G-beta repeat Arrestin_N PF00339.29 OAG37064.1 - 2.3e-10 40.7 0.0 4.4e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain ANAPC4_WD40 PF12894.7 OAG37064.1 - 1e-07 32.1 0.0 0.13 12.5 0.0 4.5 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OAG37064.1 - 0.0014 18.6 0.0 0.023 14.6 0.0 2.3 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.12 OAG37064.1 - 0.0027 15.8 0.0 0.0065 14.5 0.0 1.6 1 1 1 2 2 2 1 IKI3 family LDB19 PF13002.7 OAG37064.1 - 0.026 14.2 0.0 0.054 13.2 0.0 1.6 1 0 0 1 1 1 0 Arrestin_N terminal like PD40 PF07676.12 OAG37064.1 - 0.033 14.1 0.0 4.6 7.3 0.0 2.8 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 OAG37064.1 - 0.1 11.1 0.0 0.34 9.4 0.0 1.8 2 0 0 2 2 2 0 Cytochrome D1 heme domain WD40_like PF17005.5 OAG37064.1 - 0.13 11.5 0.0 12 5.1 0.0 2.6 3 0 0 3 3 3 0 WD40-like domain Endonuclease_NS PF01223.23 OAG37065.1 - 1e-60 205.4 0.0 1.3e-60 205.0 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease SOBP PF15279.6 OAG37065.1 - 1.6 9.3 8.5 2.6 8.6 8.5 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein Zip PF02535.22 OAG37066.1 - 1.5e-24 86.8 9.9 6.5e-16 58.5 5.2 2.0 2 0 0 2 2 2 2 ZIP Zinc transporter AAA PF00004.29 OAG37067.1 - 3.6e-17 63.0 0.0 6.1e-17 62.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 OAG37067.1 - 0.0049 16.6 0.0 0.0088 15.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 OAG37067.1 - 0.017 15.5 0.1 0.067 13.6 0.1 2.1 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 OAG37067.1 - 0.018 15.3 0.6 0.48 10.7 0.0 2.8 1 1 2 3 3 3 0 AAA domain AAA_5 PF07728.14 OAG37067.1 - 0.039 13.9 0.0 0.088 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Zot PF05707.12 OAG37067.1 - 0.048 13.3 0.0 0.38 10.4 0.0 2.2 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) AAA_17 PF13207.6 OAG37067.1 - 0.049 14.0 0.0 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain DnaB_C PF03796.15 OAG37067.1 - 0.076 12.3 0.1 0.2 11.0 0.0 1.7 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain Pectate_lyase_3 PF12708.7 OAG37069.1 - 5e-79 265.1 19.0 3e-70 236.4 8.4 2.7 3 0 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 OAG37069.1 - 6.5e-06 25.8 1.5 0.0079 15.9 0.3 2.6 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Beta_helix PF13229.6 OAG37069.1 - 0.006 16.4 5.2 0.023 14.6 5.1 2.0 1 1 0 1 1 1 1 Right handed beta helix region NosD PF05048.13 OAG37069.1 - 0.05 12.9 3.0 0.098 11.9 3.0 1.4 1 0 0 1 1 1 0 Periplasmic copper-binding protein (NosD) Period_C PF12114.8 OAG37069.1 - 0.16 11.6 0.0 0.3 10.7 0.0 1.3 1 0 0 1 1 1 0 Period protein 2/3C-terminal region AMP-binding PF00501.28 OAG37070.1 - 1.4e-88 297.3 0.0 3.2e-88 296.2 0.0 1.5 2 0 0 2 2 2 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG37070.1 - 0.0042 18.0 0.8 0.011 16.6 0.8 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Methyltransf_16 PF10294.9 OAG37071.1 - 7.5e-14 51.8 0.1 4.5e-13 49.3 0.1 1.9 1 1 0 1 1 1 1 Lysine methyltransferase IBN_N PF03810.19 OAG37072.1 - 1.8e-17 63.0 1.0 2.5e-14 52.9 0.0 3.9 3 0 0 3 3 3 1 Importin-beta N-terminal domain Cse1 PF08506.10 OAG37072.1 - 3.2e-11 42.7 0.0 6.5e-11 41.7 0.0 1.5 1 0 0 1 1 1 1 Cse1 RTP1_C1 PF10363.9 OAG37072.1 - 0.0018 18.5 0.5 0.034 14.3 0.2 2.8 2 0 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_2 PF13646.6 OAG37072.1 - 0.0053 17.1 2.4 5.1 7.6 0.0 4.3 4 0 0 4 4 4 1 HEAT repeats Xpo1 PF08389.12 OAG37072.1 - 0.02 15.0 3.4 0.66 10.0 0.0 3.5 3 0 0 3 3 3 0 Exportin 1-like protein Importin_rep_6 PF18829.1 OAG37072.1 - 0.075 13.2 1.1 0.16 12.1 0.0 2.2 2 0 0 2 2 2 0 Importin repeat 6 GRIP PF01465.20 OAG37072.1 - 0.078 12.9 0.0 0.31 11.0 0.0 2.1 1 1 0 1 1 1 0 GRIP domain zf-RanBP PF00641.18 OAG37073.1 - 1e-19 69.5 10.0 7.8e-11 41.1 1.7 2.3 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others RRM_1 PF00076.22 OAG37073.1 - 1.4e-07 31.2 0.0 2.4e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNase_T PF00929.24 OAG37073.1 - 1.9e-07 31.8 0.0 2.9e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Exonuclease zf-ribbon_3 PF13248.6 OAG37073.1 - 0.51 9.8 5.2 1.1 8.7 0.4 2.9 3 0 0 3 3 3 0 zinc-ribbon domain Oxidored_molyb PF00174.19 OAG37074.1 - 1.4e-53 181.1 0.0 1.9e-53 180.6 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 OAG37074.1 - 6.5e-18 65.1 0.1 1.4e-17 64.0 0.1 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Peptidase_M20 PF01546.28 OAG37075.1 - 2.8e-29 102.3 0.0 4.4e-29 101.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 OAG37075.1 - 3e-05 23.9 0.0 5.1e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 OAG37075.1 - 0.0003 20.6 0.0 0.00061 19.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 S10_plectin PF03501.15 OAG37076.1 - 2.4e-41 139.7 0.1 3e-41 139.4 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain Ribosomal_S8e PF01201.22 OAG37077.1 - 1.4e-54 183.9 1.7 1.6e-54 183.8 1.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S8e DUF600 PF04634.12 OAG37078.1 - 0.026 14.6 0.0 0.045 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF600 RE_Bpu10I PF09549.10 OAG37078.1 - 0.084 12.5 0.1 0.11 12.1 0.1 1.2 1 0 0 1 1 1 0 Bpu10I restriction endonuclease ADH_N PF08240.12 OAG37079.1 - 2e-35 120.9 0.9 2e-35 120.9 0.9 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG37079.1 - 2.9e-15 56.4 0.0 4.7e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 OAG37079.1 - 9.6e-12 44.8 0.0 1.5e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 OAG37079.1 - 1.7e-07 32.3 0.0 2.9e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FAD_binding_3 PF01494.19 OAG37079.1 - 0.016 14.5 0.2 0.027 13.7 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain HECT PF00632.25 OAG37080.1 - 8.5e-72 242.2 0.0 1.2e-71 241.7 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) ITAM_Cys-rich PF10538.9 OAG37080.1 - 3.9 7.3 5.3 1 9.2 1.4 2.1 2 0 0 2 2 2 0 Immunoreceptor tyrosine-based activation motif GMC_oxred_N PF00732.19 OAG37081.1 - 8.3e-46 156.7 0.0 1.1e-45 156.3 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAG37081.1 - 2.4e-36 125.4 0.1 4.7e-36 124.5 0.1 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 OAG37081.1 - 3.2e-06 26.4 0.3 7.3e-06 25.3 0.1 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 OAG37081.1 - 0.00026 21.1 0.2 0.00097 19.3 0.2 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 OAG37081.1 - 0.00057 18.7 0.5 0.0077 15.0 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_9 PF13454.6 OAG37081.1 - 0.00089 19.3 0.2 0.14 12.1 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.24 OAG37081.1 - 0.003 17.2 0.2 0.02 14.5 0.0 2.2 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 OAG37081.1 - 0.0035 16.6 0.1 0.98 8.6 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAG37081.1 - 0.0048 16.2 0.0 0.044 13.0 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAG37081.1 - 0.0061 15.7 0.1 0.014 14.5 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.22 OAG37081.1 - 0.044 12.9 0.2 6.4 5.7 0.1 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A UCR_Fe-S_N PF10399.9 OAG37081.1 - 0.1 12.0 0.4 0.27 10.6 0.4 1.8 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal ApbA PF02558.16 OAG37081.1 - 0.11 12.2 0.1 0.22 11.2 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA MMR_HSR1 PF01926.23 OAG37082.1 - 1.3e-05 25.2 0.0 0.11 12.6 0.0 2.3 2 0 0 2 2 2 2 50S ribosome-binding GTPase ADH_zinc_N_2 PF13602.6 OAG37083.1 - 1.3e-17 65.1 0.0 2.2e-17 64.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 OAG37083.1 - 3.9e-11 43.0 0.1 6.9e-11 42.2 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG37083.1 - 4.4e-09 36.2 0.1 1.4e-07 31.3 0.0 2.5 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain CENP-Q PF13094.6 OAG37084.1 - 0.0029 17.8 0.5 0.0034 17.6 0.5 1.1 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit Uds1 PF15456.6 OAG37084.1 - 0.011 15.9 1.7 0.014 15.6 1.7 1.2 1 0 0 1 1 1 0 Up-regulated During Septation SlyX PF04102.12 OAG37084.1 - 0.02 15.5 1.8 0.037 14.7 1.8 1.4 1 0 0 1 1 1 0 SlyX Herpes_UL6 PF01763.16 OAG37084.1 - 0.067 11.7 0.1 0.07 11.6 0.1 1.0 1 0 0 1 1 1 0 Herpesvirus UL6 like Bromodomain PF00439.25 OAG37085.1 - 5.4e-07 29.6 0.0 2.3e-05 24.4 0.0 2.5 2 0 0 2 2 2 2 Bromodomain PI-PLC-X PF00388.19 OAG37086.1 - 1.8e-59 199.5 0.0 3.1e-59 198.7 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 OAG37086.1 - 2e-40 137.7 0.2 4.1e-40 136.7 0.2 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain PH_12 PF16457.5 OAG37086.1 - 0.00088 19.8 0.1 0.0019 18.7 0.1 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain CATSPERB PF15149.6 OAG37086.1 - 0.0097 14.5 0.1 0.018 13.6 0.1 1.3 1 0 0 1 1 1 1 Cation channel sperm-associated protein subunit beta protein family EF-hand_7 PF13499.6 OAG37086.1 - 0.061 13.8 0.3 0.15 12.5 0.3 1.7 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_6 PF13405.6 OAG37086.1 - 0.17 11.9 0.2 0.72 9.9 0.3 2.0 2 0 0 2 2 2 0 EF-hand domain DUF3431 PF11913.8 OAG37087.1 - 2.7e-68 230.0 0.0 3.6e-68 229.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) DUF4896 PF16237.5 OAG37087.1 - 0.35 10.7 4.4 1 9.3 1.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4896) Mcp5_PH PF12814.7 OAG37088.1 - 0.07 13.2 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology LRR_4 PF12799.7 OAG37089.1 - 0.2 12.2 5.0 5.8 7.5 0.2 4.9 6 0 0 6 6 6 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 OAG37089.1 - 7.9 6.8 12.2 20 5.6 0.0 5.8 7 0 0 7 7 7 0 Leucine Rich repeat Ribosomal_L5e PF17144.4 OAG37090.1 - 4.1e-81 270.8 0.3 4.1e-81 270.8 0.3 1.5 2 0 0 2 2 2 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 OAG37090.1 - 1.1e-34 119.2 8.3 1.1e-34 119.2 8.3 2.0 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Thr_synth_N PF14821.6 OAG37090.1 - 0.049 13.9 0.2 0.87 9.8 0.0 2.5 2 1 0 2 2 2 0 Threonine synthase N terminus MscS_porin PF12795.7 OAG37091.1 - 3.4 7.2 13.6 0.055 13.0 6.0 1.9 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain adh_short PF00106.25 OAG37093.1 - 1.9e-16 60.1 0.0 1.1e-15 57.6 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG37093.1 - 3.9e-13 49.5 0.0 5.8e-12 45.7 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG37093.1 - 6e-07 29.5 0.0 1e-06 28.8 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG37093.1 - 9.9e-06 25.2 0.0 1.3e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 OAG37093.1 - 6e-05 23.0 0.0 8.8e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Glyco_transf_4 PF13439.6 OAG37093.1 - 0.00071 19.6 0.0 0.0011 19.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase Family 4 p450 PF00067.22 OAG37094.1 - 1.2e-44 152.9 0.0 1.7e-44 152.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Ovate PF04844.13 OAG37094.1 - 0.061 13.3 0.1 0.14 12.2 0.1 1.5 1 0 0 1 1 1 0 Transcriptional repressor, ovate NmrA PF05368.13 OAG37095.1 - 1e-39 136.5 0.2 1.9e-39 135.6 0.2 1.3 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG37095.1 - 1.9e-14 54.0 0.3 2.7e-14 53.5 0.3 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAG37095.1 - 0.00016 21.2 0.0 0.00025 20.6 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OAG37095.1 - 0.0002 20.5 0.0 0.00038 19.5 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.18 OAG37095.1 - 0.15 12.4 0.1 0.27 11.5 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain Amidase PF01425.21 OAG37096.1 - 2.3e-73 247.7 0.1 2e-72 244.6 0.1 1.9 1 1 0 1 1 1 1 Amidase Fungal_trans_2 PF11951.8 OAG37097.1 - 1.2e-08 34.2 1.3 1.5e-07 30.5 0.2 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Ceramidase_alk PF04734.13 OAG37099.1 - 6.8e-213 707.9 0.0 7.9e-213 707.7 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 OAG37099.1 - 2.2e-56 190.3 0.0 3.2e-56 189.8 0.0 1.3 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal BCAS2 PF05700.11 OAG37100.1 - 6.1e-54 182.9 0.7 7.1e-54 182.6 0.7 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) GMC_oxred_N PF00732.19 OAG37101.1 - 2.2e-76 257.1 0.0 2.9e-76 256.7 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAG37101.1 - 4.9e-34 117.9 0.0 1.3e-33 116.5 0.0 1.7 1 1 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 OAG37101.1 - 0.00017 20.8 0.0 0.19 10.8 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 OAG37101.1 - 0.0019 17.4 0.0 0.0029 16.7 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 OAG37101.1 - 0.022 14.4 0.4 0.11 12.0 0.4 2.1 1 1 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.17 OAG37101.1 - 0.039 13.2 0.0 0.073 12.3 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.14 OAG37101.1 - 0.21 10.8 0.0 0.38 9.9 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Kelch_5 PF13854.6 OAG37102.1 - 3.9e-17 61.8 9.2 2.5e-07 30.5 0.1 4.7 4 0 0 4 4 4 3 Kelch motif Kelch_3 PF13415.6 OAG37102.1 - 7.1e-09 35.7 15.2 0.11 12.8 0.2 6.2 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_4 PF13418.6 OAG37102.1 - 1.1e-07 31.7 15.5 0.012 15.6 0.3 5.7 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_1 PF01344.25 OAG37102.1 - 3.4e-07 29.7 8.6 0.0053 16.3 1.2 4.6 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.6 OAG37102.1 - 9.5e-07 28.9 20.6 0.017 15.4 0.7 5.6 4 1 1 5 5 5 3 Kelch motif Kelch_2 PF07646.15 OAG37102.1 - 3.8e-06 26.7 10.4 0.0019 18.1 0.5 4.5 5 0 0 5 5 5 2 Kelch motif SKG6 PF08693.10 OAG37102.1 - 0.34 10.4 7.5 1.1 8.8 7.5 1.9 1 0 0 1 1 1 0 Transmembrane alpha-helix domain MFS_1 PF07690.16 OAG37104.1 - 5.2e-39 134.2 31.1 5.9e-37 127.4 32.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG37104.1 - 3.3e-12 46.0 10.2 3.3e-12 46.0 10.2 2.1 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 OAG37104.1 - 6.9e-07 28.1 4.4 1.1e-06 27.4 4.4 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) HemY_N PF07219.13 OAG37104.1 - 0.044 14.0 0.1 0.21 11.8 0.1 2.2 1 0 0 1 1 1 0 HemY protein N-terminus HDV_ag PF01517.18 OAG37104.1 - 2.6 7.8 9.4 0.72 9.6 6.3 1.5 2 0 0 2 2 2 0 Hepatitis delta virus delta antigen Ribosomal_L27A PF00828.19 OAG37106.1 - 2.1e-16 60.7 0.0 2.3e-16 60.6 0.0 1.0 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Drc1-Sld2 PF11719.8 OAG37107.1 - 1.8e-67 228.9 12.6 2.4e-67 228.5 12.6 1.1 1 0 0 1 1 1 1 DNA replication and checkpoint protein Sec1 PF00995.23 OAG37108.1 - 2.4e-126 423.3 0.0 2.8e-126 423.1 0.0 1.0 1 0 0 1 1 1 1 Sec1 family UAE_UbL PF14732.6 OAG37108.1 - 0.12 13.0 0.0 1 10.0 0.0 2.4 2 0 0 2 2 2 0 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain DUF1043 PF06295.12 OAG37108.1 - 0.65 10.0 2.1 0.95 9.5 0.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) zf_CCCH_4 PF18345.1 OAG37109.1 - 3.2e-06 27.0 2.9 5.7e-06 26.2 2.9 1.4 1 0 0 1 1 1 1 Zinc finger domain Torus PF16131.5 OAG37109.1 - 0.0015 19.2 1.3 0.0055 17.4 1.3 2.0 1 0 0 1 1 1 1 Torus domain zf-CCCH_4 PF18044.1 OAG37109.1 - 0.0028 17.4 1.1 0.0046 16.7 1.1 1.3 1 0 0 1 1 1 1 CCCH-type zinc finger Med26 PF08711.11 OAG37109.1 - 0.0034 17.4 0.4 0.012 15.6 0.3 2.0 2 0 0 2 2 2 1 TFIIS helical bundle-like domain zf-CCCH PF00642.24 OAG37109.1 - 0.01 15.7 2.1 0.017 15.1 2.1 1.3 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 OAG37109.1 - 0.014 15.6 0.8 0.034 14.4 0.8 1.5 1 0 0 1 1 1 0 Zinc-finger containing family AT_hook PF02178.19 OAG37109.1 - 0.033 14.0 2.1 0.12 12.3 2.1 2.1 1 0 0 1 1 1 0 AT hook motif zf-CCCH_2 PF14608.6 OAG37109.1 - 0.1 13.1 0.5 0.18 12.3 0.5 1.4 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger ArsA_ATPase PF02374.15 OAG37110.1 - 1.5e-111 372.5 0.0 1.7e-111 372.3 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 OAG37110.1 - 6.7e-15 55.4 0.2 4.3e-13 49.6 0.0 2.6 2 1 0 2 2 2 1 AAA domain CbiA PF01656.23 OAG37110.1 - 1.1e-12 48.1 0.0 2.2e-12 47.1 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Fer4_NifH PF00142.18 OAG37110.1 - 1.5e-06 27.9 0.1 3.8e-06 26.6 0.0 1.7 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.22 OAG37110.1 - 2.2e-06 27.4 0.1 0.00042 20.0 0.1 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain ParA PF10609.9 OAG37110.1 - 9.9e-06 25.2 2.0 0.00011 21.8 0.1 2.6 3 0 0 3 3 3 1 NUBPL iron-transfer P-loop NTPase CBP_BcsQ PF06564.12 OAG37110.1 - 0.00016 21.3 0.3 0.00065 19.2 0.0 2.1 3 0 0 3 3 3 1 Cellulose biosynthesis protein BcsQ AAA_25 PF13481.6 OAG37110.1 - 0.0061 16.2 0.2 0.017 14.7 0.2 1.9 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 OAG37110.1 - 0.024 13.9 0.0 0.043 13.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin PhoH PF02562.16 OAG37110.1 - 0.025 14.0 0.0 0.071 12.5 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein NB-ARC PF00931.22 OAG37110.1 - 0.057 12.6 0.0 0.12 11.5 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain ATPase PF06745.13 OAG37110.1 - 0.094 12.0 0.2 0.33 10.2 0.0 1.8 2 0 0 2 2 2 0 KaiC AAA_16 PF13191.6 OAG37110.1 - 0.11 12.8 0.0 0.19 12.1 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain MFS_1 PF07690.16 OAG37112.1 - 3.5e-41 141.3 17.7 4.4e-41 141.0 17.7 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG37112.1 - 2.6e-12 46.4 3.8 2.6e-11 43.0 3.8 2.3 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 OAG37112.1 - 3.3e-06 25.8 0.3 4.9e-06 25.3 0.3 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG37113.1 - 4.4e-34 117.9 17.6 7.1e-20 71.2 6.0 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 OAG37113.1 - 1.3e-06 27.3 24.1 0.0077 14.8 14.3 3.7 2 2 1 3 3 3 3 MFS/sugar transport protein MFS_1_like PF12832.7 OAG37113.1 - 1.6e-06 27.3 9.0 1.6e-06 27.3 9.0 2.6 2 1 1 3 3 3 2 MFS_1 like family Sugar_tr PF00083.24 OAG37113.1 - 4.5e-06 25.8 17.0 0.0019 17.2 9.3 3.0 3 1 0 3 3 3 2 Sugar (and other) transporter MFS_5 PF05631.14 OAG37113.1 - 0.0013 17.7 2.3 0.0023 16.9 2.3 1.3 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM OATP PF03137.20 OAG37113.1 - 0.0022 16.4 9.0 0.45 8.7 4.7 3.0 1 1 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family MFS_3 PF05977.13 OAG37113.1 - 0.13 10.7 10.4 0.092 11.1 1.3 2.2 2 0 0 2 2 2 0 Transmembrane secretion effector ECH_1 PF00378.20 OAG37114.1 - 1.7e-38 132.4 0.0 3.1e-38 131.5 0.0 1.3 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAG37114.1 - 7.7e-31 107.8 0.0 1.6e-30 106.7 0.0 1.4 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase HNH_2 PF13391.6 OAG37115.1 - 1.7e-12 47.3 0.0 3.7e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease MARVEL PF01284.23 OAG37116.1 - 7.2e-28 97.4 13.9 9e-28 97.1 13.9 1.0 1 0 0 1 1 1 1 Membrane-associating domain DUF2070 PF09843.9 OAG37116.1 - 0.071 11.4 4.4 0.077 11.3 4.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Pyr_redox_2 PF07992.14 OAG37117.1 - 1.6e-67 227.8 8.4 1.6e-67 227.8 8.4 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 OAG37117.1 - 2e-39 134.2 0.1 6.7e-39 132.6 0.1 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 OAG37117.1 - 2e-21 76.3 2.1 2e-21 76.3 2.1 2.8 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OAG37117.1 - 1.4e-08 34.3 8.9 4.3e-07 29.4 2.6 2.5 2 1 0 2 2 2 2 Glucose inhibited division protein A NAD_binding_8 PF13450.6 OAG37117.1 - 6.5e-07 29.5 4.4 0.012 15.9 0.7 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 OAG37117.1 - 7.8e-07 28.8 9.7 9.1e-07 28.6 0.2 2.7 2 1 1 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 OAG37117.1 - 9e-07 28.4 0.3 9e-07 28.4 0.3 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAG37117.1 - 1.2e-06 27.5 14.0 0.0081 14.9 1.3 4.2 4 0 0 4 4 4 4 HI0933-like protein FAD_binding_2 PF00890.24 OAG37117.1 - 5.7e-06 25.7 9.2 0.00012 21.3 2.3 3.3 3 0 0 3 3 3 1 FAD binding domain K_oxygenase PF13434.6 OAG37117.1 - 7.9e-06 25.2 0.2 0.082 12.0 0.0 2.4 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.21 OAG37117.1 - 2.7e-05 23.6 3.2 0.0027 17.0 0.6 2.9 2 1 1 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 OAG37117.1 - 0.0025 17.5 13.3 0.36 10.4 1.9 4.0 4 0 0 4 4 4 2 FAD dependent oxidoreductase 3HCDH_N PF02737.18 OAG37117.1 - 0.039 13.8 1.5 0.093 12.6 1.5 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 OAG37117.1 - 0.083 13.3 0.7 0.71 10.3 0.2 2.6 2 0 0 2 2 2 0 Putative NAD(P)-binding Lycopene_cycl PF05834.12 OAG37117.1 - 0.13 11.2 4.0 2.7 6.9 0.3 2.6 2 1 0 2 2 2 0 Lycopene cyclase protein FAD_binding_3 PF01494.19 OAG37117.1 - 0.79 8.9 10.0 1 8.5 2.7 2.9 2 1 0 2 2 2 0 FAD binding domain Amidohydro_2 PF04909.14 OAG37120.1 - 7.2e-09 35.8 0.0 1.5e-08 34.8 0.0 1.4 1 1 0 1 1 1 1 Amidohydrolase CoA_binding_2 PF13380.6 OAG37120.1 - 0.0011 19.5 0.1 0.0024 18.3 0.1 1.6 1 0 0 1 1 1 1 CoA binding domain Amidohydro_1 PF01979.20 OAG37120.1 - 0.0034 16.7 0.0 0.0065 15.8 0.0 1.5 1 1 0 1 1 1 1 Amidohydrolase family GTP_EFTU PF00009.27 OAG37122.1 - 2e-32 112.3 5.3 1.6e-30 106.1 5.3 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 OAG37122.1 - 1.5e-23 82.9 0.7 5.2e-23 81.2 0.7 1.9 1 0 0 1 1 1 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 OAG37122.1 - 1.4e-08 34.8 0.2 3.7e-08 33.5 0.2 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OAG37122.1 - 2.8e-05 23.7 0.2 5.4e-05 22.8 0.2 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU_D2 PF03144.25 OAG37122.1 - 4.5e-05 23.8 2.3 0.14 12.6 0.1 3.5 3 0 0 3 3 3 2 Elongation factor Tu domain 2 IF2_N PF04760.15 OAG37122.1 - 0.00013 21.7 0.0 0.00037 20.2 0.0 1.9 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region Arf PF00025.21 OAG37122.1 - 0.00019 21.0 0.0 0.00035 20.1 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OAG37122.1 - 0.0002 21.3 1.1 0.0015 18.4 0.2 2.3 1 1 1 2 2 2 1 RsgA GTPase Ras PF00071.22 OAG37122.1 - 0.00066 19.3 0.1 0.0013 18.3 0.1 1.5 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 OAG37122.1 - 0.011 15.2 0.2 0.033 13.6 0.2 1.7 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF2326 PF10088.9 OAG37122.1 - 0.014 15.2 0.1 0.038 13.7 0.2 1.6 2 0 0 2 2 2 0 Uncharacterised protein conserved in bacteria (DUF2326) MMR_HSR1_Xtn PF16897.5 OAG37122.1 - 0.031 14.3 0.1 0.075 13.1 0.1 1.6 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain TniB PF05621.11 OAG37122.1 - 0.041 13.3 0.0 0.084 12.3 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein Roc PF08477.13 OAG37122.1 - 0.087 13.0 0.1 0.16 12.2 0.1 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase DUF1492 PF07374.11 OAG37122.1 - 0.52 10.5 2.3 0.74 10.0 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1492) Mito_carr PF00153.27 OAG37123.1 - 2.3e-57 190.9 1.3 1.8e-18 66.2 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Fer4 PF00037.27 OAG37124.1 - 1.7e-13 49.8 16.1 2.1e-08 33.6 3.5 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 OAG37124.1 - 5.4e-13 49.3 8.7 8.9e-13 48.6 8.7 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 OAG37124.1 - 1.3e-09 38.9 6.4 3.4e-05 24.7 0.3 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 OAG37124.1 - 1.9e-09 37.5 4.5 0.00065 19.8 0.3 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 OAG37124.1 - 2.5e-09 37.1 20.5 1.2e-06 28.5 11.5 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 OAG37124.1 - 3.1e-08 33.7 9.2 5.1e-08 32.9 9.2 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 OAG37124.1 - 1.1e-07 32.2 19.4 1.7e-05 25.2 10.6 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 OAG37124.1 - 4.1e-06 26.6 11.7 0.0082 16.2 1.7 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 OAG37124.1 - 5.5e-06 26.5 9.7 0.00031 21.0 1.1 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.7 OAG37124.1 - 1.6e-05 24.7 16.3 0.0069 16.4 4.8 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 OAG37124.1 - 0.00025 21.5 12.0 0.0071 16.9 12.5 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_3 PF12798.7 OAG37124.1 - 0.0076 17.1 14.9 0.018 15.9 3.5 2.3 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_13 PF13370.6 OAG37124.1 - 0.012 16.1 14.4 0.33 11.5 3.6 2.6 2 1 1 3 3 3 0 4Fe-4S single cluster domain of Ferredoxin I c-SKI_SMAD_bind PF08782.10 OAG37124.1 - 0.03 14.5 4.7 1.4 9.2 0.3 2.2 1 1 1 2 2 2 0 c-SKI Smad4 binding domain Fer4_18 PF13746.6 OAG37124.1 - 0.11 12.6 8.9 65 3.8 8.6 2.2 1 1 0 1 1 1 0 4Fe-4S dicluster domain hGDE_central PF14702.6 OAG37124.1 - 0.18 11.5 0.0 0.26 10.9 0.0 1.1 1 0 0 1 1 1 0 Central domain of human glycogen debranching enzyme Fer4_22 PF17179.4 OAG37124.1 - 0.3 12.0 10.8 3 8.8 1.7 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain EPF PF17181.4 OAG37124.1 - 0.62 10.1 5.2 0.41 10.7 0.4 2.2 2 0 0 2 2 2 0 Epidermal patterning factor proteins ETF_QO PF05187.13 OAG37124.1 - 0.78 9.9 5.8 0.92 9.7 2.2 2.1 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_15 PF13459.6 OAG37124.1 - 1.3 9.8 11.8 7.6 7.4 4.3 3.0 2 1 0 2 2 2 0 4Fe-4S single cluster domain CoA_transf_3 PF02515.17 OAG37125.1 - 2.7e-107 359.1 0.0 3.1e-107 358.9 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III Acyl-CoA_dh_1 PF00441.24 OAG37126.1 - 5.8e-36 124.0 10.2 1.1e-35 123.1 10.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 OAG37126.1 - 3.8e-23 82.3 2.1 3.8e-23 82.3 0.1 2.0 2 1 1 3 3 3 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 OAG37126.1 - 3.8e-18 65.5 0.0 7.1e-18 64.6 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 OAG37126.1 - 4.4e-14 52.9 6.4 4.4e-14 52.9 6.4 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Glucosaminidase PF01832.20 OAG37126.1 - 0.19 12.2 0.3 1.3 9.6 0.0 2.1 2 0 0 2 2 2 0 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase Rick_17kDa_Anti PF05433.15 OAG37127.1 - 4.1e-05 23.4 15.5 4.1e-05 23.4 15.5 2.0 2 0 0 2 2 2 1 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.6 OAG37127.1 - 0.0045 17.0 13.5 0.0045 17.0 13.5 1.7 2 0 0 2 2 2 1 Glycine zipper Gly-zipper_YMGG PF13441.6 OAG37127.1 - 0.0063 16.2 14.0 0.012 15.3 14.0 1.5 1 0 0 1 1 1 1 YMGG-like Gly-zipper TraT PF05818.12 OAG37127.1 - 0.039 13.6 1.9 0.058 13.1 1.9 1.5 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein DUF2076 PF09849.9 OAG37127.1 - 0.11 12.5 13.6 0.17 11.9 13.6 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Sugar_tr PF00083.24 OAG37128.1 - 1.3e-86 291.3 18.1 1.5e-86 291.1 18.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG37128.1 - 5.5e-18 65.0 31.4 8.4e-13 48.0 9.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 OAG37128.1 - 0.0041 16.0 12.3 0.1 11.4 0.3 2.4 1 1 1 2 2 2 2 MFS_1 like family ABM PF03992.16 OAG37129.1 - 0.00024 21.1 4.1 0.00046 20.2 2.2 2.1 2 0 0 2 2 2 1 Antibiotic biosynthesis monooxygenase AtuA PF07287.11 OAG37130.1 - 3e-116 388.0 0.1 6.1e-115 383.7 0.1 2.0 1 1 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA EthD PF07110.11 OAG37131.1 - 0.0047 18.1 0.0 5.5 8.2 0.0 2.4 2 0 0 2 2 2 2 EthD domain DUF4286 PF14114.6 OAG37131.1 - 0.05 14.1 0.0 19 5.8 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4286) p450 PF00067.22 OAG37132.1 - 1.4e-56 192.2 0.0 1.8e-56 191.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Skp1 PF01466.19 OAG37132.1 - 0.17 12.0 0.0 0.4 10.8 0.0 1.6 1 0 0 1 1 1 0 Skp1 family, dimerisation domain DUF3425 PF11905.8 OAG37133.1 - 5.2e-05 23.2 0.1 0.00022 21.2 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 OAG37133.1 - 0.0092 16.1 12.8 0.013 15.6 9.4 2.3 1 1 1 2 2 2 1 bZIP transcription factor Seryl_tRNA_N PF02403.22 OAG37133.1 - 0.099 12.9 3.7 0.18 12.0 3.7 1.5 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Uso1_p115_C PF04871.13 OAG37133.1 - 3.2 8.1 8.5 1.1 9.6 5.6 1.7 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Fungal_trans PF04082.18 OAG37134.1 - 1.6e-23 83.1 0.0 2.7e-23 82.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain FMO-like PF00743.19 OAG37135.1 - 1.3e-20 73.4 0.1 2.2e-20 72.6 0.1 1.3 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OAG37135.1 - 5.1e-10 39.4 0.0 1.7e-09 37.8 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 OAG37135.1 - 1.2e-05 24.7 0.0 0.00011 21.6 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAG37135.1 - 0.001 18.8 0.0 0.0046 16.6 0.0 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 OAG37135.1 - 0.0018 17.5 0.0 0.0071 15.5 0.0 1.9 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 OAG37135.1 - 0.0075 15.5 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAG37135.1 - 0.008 16.2 0.0 0.015 15.3 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding Thi4 PF01946.17 OAG37135.1 - 0.086 12.1 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Abhydrolase_3 PF07859.13 OAG37136.1 - 4e-51 173.9 0.0 5.1e-51 173.5 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 OAG37136.1 - 5e-15 55.4 0.1 1.7e-14 53.6 0.1 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.7 OAG37136.1 - 0.00059 20.5 0.7 0.00059 20.5 0.7 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Say1_Mug180 PF10340.9 OAG37136.1 - 0.00067 18.6 0.0 0.00094 18.1 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase AMP-binding PF00501.28 OAG37137.1 - 1.9e-93 313.3 0.0 2.6e-93 312.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG37137.1 - 1.4e-12 48.4 0.1 3.2e-12 47.3 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain adh_short_C2 PF13561.6 OAG37139.1 - 9.1e-46 156.3 0.0 1.2e-45 155.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG37139.1 - 5.1e-39 133.8 0.0 1.1e-38 132.6 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 OAG37139.1 - 3e-13 50.1 0.0 5.2e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG37139.1 - 0.0004 19.9 0.0 0.27 10.6 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAG37139.1 - 0.005 16.3 0.0 0.98 8.8 0.0 2.2 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase B12-binding PF02310.19 OAG37139.1 - 0.028 14.5 0.1 0.059 13.4 0.1 1.5 1 0 0 1 1 1 0 B12 binding domain Acyl-CoA_dh_1 PF00441.24 OAG37140.1 - 1.1e-21 77.6 1.4 2.1e-21 76.7 1.4 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 OAG37140.1 - 3.9e-13 49.4 0.0 7.6e-13 48.5 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 OAG37140.1 - 8.7e-12 45.7 0.0 1.6e-11 44.9 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 OAG37140.1 - 3.2e-06 27.5 0.1 6.7e-06 26.4 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Zn_clus PF00172.18 OAG37141.1 - 4.2e-07 30.0 10.6 8.1e-07 29.1 10.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAG37141.1 - 6.4e-06 25.4 0.6 3.4e-05 23.0 0.6 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG37142.1 - 1.4e-08 34.7 12.2 2.4e-08 33.9 12.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3425 PF11905.8 OAG37142.1 - 0.00012 22.1 0.0 0.00021 21.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) SnoaL_2 PF12680.7 OAG37143.1 - 0.00048 20.7 0.0 0.00077 20.1 0.0 1.4 1 1 0 1 1 1 1 SnoaL-like domain RAC_head PF16717.5 OAG37144.1 - 3.9e-29 101.5 3.8 3.9e-29 101.5 3.8 3.2 3 1 0 3 3 3 1 Ribosome-associated complex head domain DnaJ PF00226.31 OAG37144.1 - 4.5e-19 68.3 1.8 1.6e-18 66.6 1.8 2.0 1 0 0 1 1 1 1 DnaJ domain Phage_head_fibr PF11133.8 OAG37144.1 - 0.018 14.4 2.1 0.028 13.8 2.1 1.2 1 0 0 1 1 1 0 Head fiber protein Endonuc_Holl PF10107.9 OAG37144.1 - 0.057 13.3 9.9 0.18 11.7 9.9 1.9 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase Radial_spoke_3 PF06098.11 OAG37144.1 - 1.1 8.4 21.5 0.061 12.6 15.0 2.1 2 0 0 2 2 2 0 Radial spoke protein 3 Complex1_LYR PF05347.15 OAG37145.1 - 0.0032 17.5 0.0 0.0053 16.8 0.0 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Phage_TAC_12 PF12363.8 OAG37145.1 - 0.12 12.8 0.0 0.16 12.4 0.0 1.1 1 0 0 1 1 1 0 Phage tail assembly chaperone protein, TAC RRM_1 PF00076.22 OAG37146.1 - 3e-09 36.6 0.0 5.2e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 OAG37146.1 - 0.0071 16.3 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Sterol_MT_C PF08498.10 OAG37147.1 - 2.9e-28 97.9 0.2 5.1e-28 97.2 0.2 1.4 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 OAG37147.1 - 5.2e-18 65.5 0.0 9.4e-18 64.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG37147.1 - 7.8e-17 61.8 0.0 1.4e-16 60.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG37147.1 - 8.3e-15 54.9 0.0 1.5e-14 54.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 OAG37147.1 - 3.6e-10 39.6 0.0 5.3e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 OAG37147.1 - 1.4e-09 38.0 0.0 2.2e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG37147.1 - 2.3e-09 37.9 0.0 4.9e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAG37147.1 - 3.2e-07 29.9 0.0 5.2e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_29 PF03141.16 OAG37147.1 - 0.00039 19.1 0.0 0.00052 18.7 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PCMT PF01135.19 OAG37147.1 - 0.0024 17.7 0.0 0.0036 17.1 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 OAG37147.1 - 0.0058 16.1 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_15 PF09445.10 OAG37147.1 - 0.04 13.5 0.0 0.064 12.8 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase RrnaAD PF00398.20 OAG37147.1 - 0.073 12.1 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase MTS PF05175.14 OAG37147.1 - 0.085 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Asp PF00026.23 OAG37148.1 - 1.9e-62 211.5 4.0 2.8e-62 210.9 4.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OAG37148.1 - 9.5e-10 39.0 0.6 6.8e-07 29.7 0.6 3.1 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.6 OAG37148.1 - 6.3e-05 23.5 0.1 0.35 11.5 0.1 3.9 3 1 0 3 3 3 2 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 OAG37148.1 - 0.0022 18.6 5.7 0.7 10.6 0.3 4.1 3 1 0 3 3 3 2 Aspartyl protease LrgB PF04172.16 OAG37148.1 - 0.12 11.9 1.5 0.26 10.8 1.5 1.5 1 0 0 1 1 1 0 LrgB-like family TAXi_C PF14541.6 OAG37148.1 - 0.13 12.1 0.0 0.28 10.9 0.0 1.6 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal Amidohydro_2 PF04909.14 OAG37149.1 - 4.6e-34 118.5 0.3 5.7e-34 118.2 0.3 1.1 1 0 0 1 1 1 1 Amidohydrolase GPP34 PF05719.11 OAG37150.1 - 2.8e-68 230.0 0.3 4.6e-68 229.3 0.3 1.3 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) SpoIID PF08486.10 OAG37150.1 - 0.14 12.7 0.0 0.3 11.7 0.0 1.5 1 0 0 1 1 1 0 Stage II sporulation protein DUF347 PF03988.12 OAG37152.1 - 5 7.4 7.4 1.2 9.3 0.1 2.9 3 0 0 3 3 3 0 Repeat of Unknown Function (DUF347) Ank_4 PF13637.6 OAG37153.1 - 2.8e-31 107.5 13.7 1.2e-06 28.9 0.0 8.7 7 1 1 8 8 8 7 Ankyrin repeats (many copies) Ank_2 PF12796.7 OAG37153.1 - 2e-30 105.2 15.0 4.3e-09 36.8 0.3 7.5 5 1 2 8 8 8 5 Ankyrin repeats (3 copies) Ank PF00023.30 OAG37153.1 - 1e-23 82.6 23.8 0.001 19.4 0.0 12.0 12 0 0 12 12 12 6 Ankyrin repeat Ank_5 PF13857.6 OAG37153.1 - 6.1e-22 77.4 25.6 9.4e-06 25.8 0.2 10.0 8 1 2 10 10 10 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG37153.1 - 3e-19 67.1 21.4 0.015 15.7 0.1 11.6 11 0 0 11 11 11 6 Ankyrin repeat Fer4_15 PF13459.6 OAG37153.1 - 0.033 14.9 0.0 0.33 11.7 0.0 2.5 2 0 0 2 2 2 0 4Fe-4S single cluster domain GDPD_2 PF13653.6 OAG37153.1 - 0.071 13.6 0.0 38 4.9 0.0 3.6 3 0 0 3 3 3 0 Glycerophosphoryl diester phosphodiesterase family DUF4470 PF14737.6 OAG37154.1 - 1.4e-15 57.2 0.1 6.9e-15 55.0 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4470) DDE_Tnp_IS240 PF13610.6 OAG37155.1 - 0.5 10.6 9.4 6.6 7.0 0.0 3.1 2 1 0 3 3 3 0 DDE domain DUF4407 PF14362.6 OAG37155.1 - 1.2 8.4 32.0 4.5e+03 -3.3 31.6 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3782 PF12644.7 OAG37155.1 - 1.8 8.8 0.0 1.8 8.8 0.0 4.7 4 1 0 4 4 4 0 Protein of unknown function (DUF3782) Filament PF00038.21 OAG37155.1 - 1.9 8.0 40.6 8.2 5.9 38.8 2.5 1 1 0 1 1 1 0 Intermediate filament protein V_ATPase_I PF01496.19 OAG37155.1 - 3.7 5.4 15.5 5.9 4.7 15.5 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF5401 PF17380.2 OAG37155.1 - 4.2 5.3 29.9 5.7 4.9 29.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5401) Ank_2 PF12796.7 OAG37156.1 - 0.0023 18.5 0.0 0.0031 18.1 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OAG37156.1 - 0.0061 17.0 0.0 3.6 8.4 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeat zf-C2H2_jaz PF12171.8 OAG37157.1 - 3.2e-12 46.4 0.5 3.3e-05 24.0 0.1 2.9 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OAG37157.1 - 4.2e-10 39.7 2.0 0.00024 21.4 0.1 2.7 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 OAG37157.1 - 2.2e-07 31.1 12.3 0.0051 17.5 0.2 5.2 5 0 0 5 5 5 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 OAG37157.1 - 1.7e-06 27.8 2.4 0.0021 18.0 0.2 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 OAG37157.1 - 4.9e-06 26.7 3.6 0.00065 20.0 0.2 4.4 5 0 0 5 5 5 2 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 OAG37157.1 - 1.1e-05 25.6 3.6 0.058 13.7 0.1 2.7 2 1 1 3 3 2 2 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.6 OAG37157.1 - 0.00084 19.2 4.9 0.057 13.3 0.2 3.4 3 0 0 3 3 3 1 zinc-finger of a C2HC-type zf-C2H2_8 PF15909.5 OAG37157.1 - 0.0062 16.8 2.0 0.0064 16.8 0.6 1.8 2 0 0 2 2 2 1 C2H2-type zinc ribbon zf_C2H2_ZHX PF18387.1 OAG37157.1 - 0.029 14.0 1.5 2.6 7.8 0.1 2.7 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain DUF629 PF04780.12 OAG37157.1 - 0.043 12.3 1.1 0.41 9.1 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF629) zf-C2HE PF16278.5 OAG37157.1 - 0.068 13.6 7.0 1.1 9.7 0.4 3.1 2 1 1 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger DUF2197 PF09963.9 OAG37157.1 - 0.12 12.6 0.1 0.12 12.6 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) zf-3CxxC_2 PF17180.4 OAG37157.1 - 0.23 12.2 2.1 1.5 9.6 0.1 2.9 3 0 0 3 3 3 0 Zinc-binding domain zf-LYAR PF08790.11 OAG37157.1 - 0.26 11.2 3.0 0.66 9.9 0.1 2.6 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger CpXC PF14353.6 OAG37157.1 - 0.34 11.0 1.8 3.9 7.6 0.2 2.4 2 0 0 2 2 2 0 CpXC protein HNH_5 PF14279.6 OAG37157.1 - 0.47 10.3 4.0 15 5.5 0.9 3.2 2 1 0 2 2 2 0 HNH endonuclease C1_4 PF07975.12 OAG37157.1 - 0.69 10.2 4.4 0.32 11.3 1.4 1.9 2 0 0 2 2 2 0 TFIIH C1-like domain zf-AN1 PF01428.16 OAG37157.1 - 1.6 8.9 6.8 6.2 7.1 0.1 3.0 3 0 0 3 3 3 0 AN1-like Zinc finger LIM PF00412.22 OAG37157.1 - 5.1 7.4 7.4 1.3 9.3 0.4 2.7 3 1 0 3 3 3 0 LIM domain Zn-ribbon_8 PF09723.10 OAG37157.1 - 9.4 6.4 10.6 16 5.7 0.3 3.1 2 1 1 3 3 3 0 Zinc ribbon domain Ribosomal_S2 PF00318.20 OAG37158.1 - 6e-65 218.5 0.1 3.7e-64 215.9 0.1 2.0 1 1 0 1 1 1 1 Ribosomal protein S2 DUF2528 PF10800.8 OAG37158.1 - 0.072 13.7 0.0 0.16 12.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2528) RNase_H PF00075.24 OAG37159.1 - 5e-14 52.7 0.0 7.8e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.6 OAG37159.1 - 0.081 12.7 0.0 4.9 7.0 0.0 2.3 2 0 0 2 2 2 0 Reverse transcriptase-like GGACT PF06094.12 OAG37160.1 - 1.1e-08 35.7 0.9 1e-07 32.6 0.0 2.3 2 0 0 2 2 2 1 Gamma-glutamyl cyclotransferase, AIG2-like FMN_dh PF01070.18 OAG37162.1 - 7e-113 377.2 0.0 8.4e-113 376.9 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 OAG37162.1 - 6.6e-20 71.0 0.0 1.2e-19 70.2 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain IMPDH PF00478.25 OAG37162.1 - 3.5e-06 26.3 0.0 0.00036 19.6 0.0 2.9 2 1 1 3 3 3 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 OAG37162.1 - 0.00074 19.0 0.0 0.0012 18.3 0.0 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase Glu_synthase PF01645.17 OAG37162.1 - 0.0062 15.7 0.0 0.011 14.9 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase HpcH_HpaI PF03328.14 OAG37163.1 - 3.3e-35 121.2 0.0 4.4e-35 120.8 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family TauD PF02668.16 OAG37164.1 - 3.4e-52 177.9 1.1 4e-52 177.6 1.1 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family TRI12 PF06609.13 OAG37165.1 - 1.6e-76 258.0 21.4 2.1e-76 257.6 21.4 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG37165.1 - 6.6e-28 97.7 61.6 4e-26 91.8 51.5 3.1 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG37165.1 - 3.7e-14 52.4 8.4 3.7e-14 52.4 8.4 3.7 2 1 1 4 4 4 1 Sugar (and other) transporter DUF4149 PF13664.6 OAG37165.1 - 0.009 16.3 1.8 0.009 16.3 1.8 4.0 5 0 0 5 5 5 1 Domain of unknown function (DUF4149) DUF1769 PF08588.10 OAG37166.1 - 5.6e-28 96.9 0.1 1.5e-27 95.6 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) MFS_1 PF07690.16 OAG37167.1 - 3.2e-06 26.3 68.0 1.9e-05 23.8 58.1 3.1 1 1 0 1 1 1 1 Major Facilitator Superfamily p450 PF00067.22 OAG37169.1 - 1.6e-46 159.0 0.0 6e-46 157.1 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 TPR_12 PF13424.6 OAG37170.1 - 2.5e-21 75.7 7.9 1.4e-07 31.7 0.0 7.4 3 1 4 7 7 7 5 Tetratricopeptide repeat TPR_10 PF13374.6 OAG37170.1 - 4.3e-18 64.6 11.6 0.0017 18.1 0.0 8.7 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_19 PF14559.6 OAG37170.1 - 3.1e-08 34.0 1.2 0.27 11.8 0.0 5.8 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 OAG37170.1 - 6.9e-07 28.9 3.0 0.29 11.3 0.0 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat Abhydrolase_6 PF12697.7 OAG37170.1 - 3.9e-05 24.3 0.3 0.00043 20.9 0.0 2.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family TPR_2 PF07719.17 OAG37170.1 - 0.0021 18.0 0.9 5.8 7.3 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat NB-ARC PF00931.22 OAG37170.1 - 0.0023 17.2 0.0 0.067 12.4 0.0 2.8 2 1 0 2 2 2 1 NB-ARC domain AAA_16 PF13191.6 OAG37170.1 - 0.031 14.7 0.4 0.13 12.6 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_33 PF13671.6 OAG37170.1 - 0.059 13.5 0.2 0.29 11.3 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 OAG37170.1 - 0.087 13.1 0.0 0.37 11.1 0.0 2.1 1 0 0 1 1 1 0 AAA domain PPR PF01535.20 OAG37170.1 - 0.13 12.5 2.4 19 5.8 0.0 4.2 4 0 0 4 4 4 0 PPR repeat TPR_17 PF13431.6 OAG37170.1 - 0.27 11.7 1.9 1.7 9.2 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat CCDC84 PF14968.6 OAG37172.1 - 0.082 12.5 3.8 0.096 12.3 3.8 1.1 1 0 0 1 1 1 0 Coiled coil protein 84 V-ATPase_G_2 PF16999.5 OAG37172.1 - 1.8 9.0 6.9 2.2 8.8 0.7 2.3 1 1 1 2 2 2 0 Vacuolar (H+)-ATPase G subunit RIFIN PF02009.16 OAG37172.1 - 2.8 7.7 8.8 3.5 7.4 8.8 1.1 1 0 0 1 1 1 0 Rifin Fungal_trans_2 PF11951.8 OAG37173.1 - 1.7e-14 53.5 0.1 3.8e-14 52.3 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain WW PF00397.26 OAG37174.1 - 1e-11 44.7 0.6 2.3e-11 43.6 0.6 1.7 1 0 0 1 1 1 1 WW domain DUF4585 PF15232.6 OAG37174.1 - 0.0071 16.4 0.0 0.033 14.2 0.0 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4585) GST_N_3 PF13417.6 OAG37175.1 - 1e-16 61.1 0.0 1.8e-16 60.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OAG37175.1 - 2.4e-14 53.3 0.0 5e-14 52.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 OAG37175.1 - 5.9e-13 49.0 0.0 1.3e-12 47.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_5 PF16865.5 OAG37175.1 - 0.00036 21.1 0.0 0.00067 20.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 OAG37175.1 - 0.00085 19.5 0.0 0.0017 18.5 0.0 1.6 1 0 0 1 1 1 1 Glutaredoxin GST_C PF00043.25 OAG37175.1 - 0.0035 17.5 0.1 0.0061 16.8 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Abhydrolase_1 PF00561.20 OAG37176.1 - 6.9e-27 94.7 0.2 3.4e-26 92.4 0.2 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAG37176.1 - 1.9e-23 83.0 0.2 7.7e-16 58.1 0.1 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OAG37176.1 - 3e-19 70.5 0.0 4e-19 70.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 OAG37176.1 - 4e-07 29.7 0.1 0.005 16.3 0.0 2.4 2 1 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_5 PF12695.7 OAG37176.1 - 7e-07 29.1 0.0 0.00052 19.8 0.0 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase family Ndr PF03096.14 OAG37176.1 - 0.00044 19.0 0.0 0.0082 14.9 0.0 2.0 2 0 0 2 2 2 1 Ndr family Ser_hydrolase PF06821.13 OAG37176.1 - 0.0005 20.0 0.0 0.014 15.3 0.0 2.4 2 1 0 2 2 2 1 Serine hydrolase Abhydrolase_4 PF08386.10 OAG37176.1 - 0.00065 19.8 0.0 0.0091 16.1 0.0 2.6 3 0 0 3 3 3 1 TAP-like protein Abhydrolase_2 PF02230.16 OAG37176.1 - 0.002 18.0 0.0 0.022 14.5 0.0 2.4 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase BAAT_C PF08840.11 OAG37176.1 - 0.014 15.4 0.1 0.062 13.2 0.1 1.9 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF915 PF06028.11 OAG37176.1 - 0.016 14.5 0.0 0.052 12.9 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) AIB PF15334.6 OAG37176.1 - 0.021 14.2 0.2 0.03 13.6 0.2 1.1 1 0 0 1 1 1 0 Aurora kinase A and ninein interacting protein PGAP1 PF07819.13 OAG37176.1 - 0.022 14.5 0.0 0.24 11.1 0.0 2.2 2 1 0 2 2 2 0 PGAP1-like protein FSH1 PF03959.13 OAG37176.1 - 0.029 14.1 0.0 0.042 13.5 0.0 1.5 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Chlorophyllase2 PF12740.7 OAG37176.1 - 0.032 13.2 0.0 0.092 11.6 0.0 1.7 1 1 0 1 1 1 0 Chlorophyllase enzyme PAF-AH_p_II PF03403.13 OAG37176.1 - 0.038 12.5 0.1 3.2 6.2 0.0 2.7 2 1 1 3 3 3 0 Platelet-activating factor acetylhydrolase, isoform II MTD PF01993.18 OAG37176.1 - 0.04 13.2 0.0 0.06 12.7 0.0 1.2 1 0 0 1 1 1 0 methylene-5,6,7,8-tetrahydromethanopterin dehydrogenase DLH PF01738.18 OAG37176.1 - 0.042 13.4 0.0 0.13 11.8 0.0 1.7 2 0 0 2 2 2 0 Dienelactone hydrolase family DUF1749 PF08538.10 OAG37176.1 - 0.14 11.2 0.0 0.69 8.9 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1749) HSP20 PF00011.21 OAG37177.1 - 1.1e-17 64.0 0.3 1.8e-11 44.1 0.0 2.2 2 0 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 OAG37177.1 - 9.6e-07 28.3 0.0 0.046 13.3 0.0 2.3 2 0 0 2 2 2 2 HSP20-like domain found in ArsA SMYLE_N PF18615.1 OAG37177.1 - 0.15 11.6 2.5 0.21 11.1 2.5 1.2 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain BUD22 PF09073.10 OAG37182.1 - 0.0034 16.8 9.1 0.0034 16.8 9.1 2.5 3 0 0 3 3 3 1 BUD22 DUF4746 PF15928.5 OAG37182.1 - 0.1 12.0 10.5 0.22 10.9 10.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) tRNA_bind_2 PF13725.6 OAG37182.1 - 1.8 8.2 12.3 1.5 8.5 10.2 1.9 2 0 0 2 2 2 0 Possible tRNA binding domain CobT PF06213.12 OAG37182.1 - 3.4 7.0 23.1 7.3 5.9 17.2 2.4 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT Zip PF02535.22 OAG37182.1 - 7.5 5.7 9.5 0.23 10.7 2.9 1.7 2 0 0 2 2 2 0 ZIP Zinc transporter Asp-B-Hydro_N PF05279.11 OAG37182.1 - 7.5 6.5 19.6 16 5.4 19.6 1.5 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region TPP_enzyme_N PF02776.18 OAG37184.1 - 1.9e-24 86.2 1.4 2.8e-24 85.6 0.4 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 OAG37184.1 - 1.3e-16 60.7 0.1 1.5e-15 57.3 0.0 2.4 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 OAG37184.1 - 9.3e-16 57.8 0.0 2.1e-15 56.6 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain MmgE_PrpD PF03972.14 OAG37185.1 - 3.8e-100 335.5 0.0 4.6e-100 335.2 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family 2OG-FeII_Oxy PF03171.20 OAG37186.1 - 1.8e-16 60.5 0.1 4.5e-16 59.2 0.1 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 OAG37186.1 - 5.9e-14 52.8 0.0 1e-13 52.0 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal DUF5463 PF17551.2 OAG37187.1 - 1.3 9.0 3.8 2.7 8.0 0.5 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5463) MFS_1 PF07690.16 OAG37188.1 - 1.7e-32 112.7 29.6 2.5e-32 112.2 29.6 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG37188.1 - 7.5e-09 35.0 19.4 2.3e-08 33.4 19.4 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter 60KD_IMP PF02096.20 OAG37188.1 - 0.046 13.6 1.0 0.75 9.7 0.1 2.5 2 0 0 2 2 2 0 60Kd inner membrane protein SVIP PF15811.5 OAG37188.1 - 0.16 12.4 0.3 0.32 11.5 0.3 1.4 1 0 0 1 1 1 0 Small VCP/p97-interacting protein MFS_4 PF06779.14 OAG37188.1 - 1.5 8.0 21.5 0.24 10.7 9.2 2.3 1 1 1 2 2 2 0 Uncharacterised MFS-type transporter YbfB Sugar_tr PF00083.24 OAG37189.1 - 1.8e-78 264.4 18.1 6.2e-78 262.7 18.1 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG37189.1 - 1.3e-22 80.3 32.5 0.01 14.8 18.8 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 OAG37189.1 - 0.00012 20.7 1.0 0.00012 20.7 1.0 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Rick_17kDa_Anti PF05433.15 OAG37189.1 - 0.069 13.0 1.2 0.88 9.5 0.1 2.6 2 0 0 2 2 2 0 Glycine zipper 2TM domain ANTH PF07651.16 OAG37190.1 - 5.3e-60 202.8 0.0 6.6e-60 202.4 0.0 1.1 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.20 OAG37190.1 - 1.9e-06 28.0 0.0 3.1e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 ENTH domain Pkinase PF00069.25 OAG37191.1 - 2.5e-40 138.5 0.0 1.3e-39 136.2 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG37191.1 - 6.4e-26 91.2 0.0 9.7e-26 90.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OAG37191.1 - 0.032 14.2 0.3 0.18 11.7 0.1 2.4 2 1 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 OAG37191.1 - 0.046 13.1 0.0 0.084 12.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OAG37191.1 - 0.092 12.0 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Cation_efflux PF01545.21 OAG37192.1 - 7.9e-26 91.0 12.9 1e-25 90.7 12.9 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 OAG37192.1 - 9.1e-07 28.9 0.0 1.9e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter IncD PF17628.2 OAG37192.1 - 0.12 12.1 0.3 0.25 11.1 0.3 1.4 1 0 0 1 1 1 0 Inclusion membrane protein D Glyco_hydro_79C PF16862.5 OAG37193.1 - 1.3e-20 74.2 0.3 1.3e-20 74.2 0.3 2.5 3 0 0 3 3 3 1 Glycosyl hydrolase family 79 C-terminal beta domain Nepo_coat PF03391.15 OAG37193.1 - 0.067 12.7 2.8 0.15 11.6 2.8 1.6 1 0 0 1 1 1 0 Nepovirus coat protein, central domain DUF1180 PF06679.12 OAG37193.1 - 5.2 7.5 6.0 11 6.4 6.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) AF-4 PF05110.13 OAG37193.1 - 7 4.6 12.5 9.6 4.1 12.5 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein PRP9_N PF16958.5 OAG37194.1 - 0.0048 16.9 1.6 0.0073 16.3 1.6 1.2 1 0 0 1 1 1 1 Pre-mRNA-splicing factor PRP9 N-terminus Mid2 PF04478.12 OAG37196.1 - 6.2e-06 26.1 0.1 9.1e-06 25.6 0.1 1.4 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Protocadherin PF08374.11 OAG37196.1 - 0.00063 19.8 0.5 0.0047 16.9 0.2 1.9 1 1 1 2 2 2 1 Protocadherin CD34_antigen PF06365.12 OAG37196.1 - 0.00067 19.3 0.2 0.001 18.7 0.2 1.2 1 1 0 1 1 1 1 CD34/Podocalyxin family DUF2207 PF09972.9 OAG37196.1 - 0.0058 15.4 0.0 0.0067 15.3 0.0 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) DAG1 PF05454.11 OAG37196.1 - 0.0062 16.0 0.1 0.0076 15.7 0.1 1.2 1 0 0 1 1 1 1 Dystroglycan (Dystrophin-associated glycoprotein 1) Adeno_E3_CR2 PF02439.15 OAG37196.1 - 0.0066 16.2 7.2 0.012 15.4 7.2 1.3 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 MLANA PF14991.6 OAG37196.1 - 0.008 16.5 0.1 0.01 16.1 0.1 1.3 1 0 0 1 1 1 1 Protein melan-A Synaptobrevin PF00957.21 OAG37196.1 - 0.013 15.2 0.1 0.024 14.4 0.1 1.4 1 0 0 1 1 1 0 Synaptobrevin DUF4446 PF14584.6 OAG37196.1 - 0.013 15.4 0.1 0.021 14.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) EphA2_TM PF14575.6 OAG37196.1 - 0.017 16.0 0.2 0.027 15.4 0.2 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Peptidase_M56 PF05569.11 OAG37196.1 - 0.021 14.0 0.0 0.027 13.7 0.0 1.1 1 0 0 1 1 1 0 BlaR1 peptidase M56 DUF4514 PF14986.6 OAG37196.1 - 0.022 14.7 0.4 0.039 13.9 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4514) Rhabdo_glycop PF00974.18 OAG37196.1 - 0.027 12.9 0.1 0.036 12.5 0.1 1.2 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein YibE_F PF07907.11 OAG37196.1 - 0.028 13.9 0.0 0.035 13.6 0.0 1.2 1 0 0 1 1 1 0 YibE/F-like protein Shisa PF13908.6 OAG37196.1 - 0.029 14.6 0.1 0.036 14.3 0.1 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF3852 PF12963.7 OAG37196.1 - 0.037 14.4 0.0 0.059 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3852) NDUF_B4 PF07225.12 OAG37196.1 - 0.055 13.4 0.0 0.09 12.7 0.0 1.4 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) LRR19-TM PF15176.6 OAG37196.1 - 0.07 13.1 0.1 0.1 12.6 0.1 1.3 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain Coiled-coil_56 PF09813.9 OAG37196.1 - 0.071 13.2 0.3 0.23 11.6 0.1 1.8 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 56 DUF5305 PF17231.2 OAG37196.1 - 0.078 12.4 0.0 0.089 12.2 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5305) TMEM52 PF14979.6 OAG37196.1 - 0.078 12.9 0.1 0.1 12.5 0.1 1.3 1 0 0 1 1 1 0 Transmembrane 52 PRIMA1 PF16101.5 OAG37196.1 - 0.096 12.7 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 DUF4448 PF14610.6 OAG37196.1 - 0.1 12.4 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Orf78 PF06024.12 OAG37196.1 - 0.12 12.7 0.1 0.19 12.0 0.1 1.4 1 1 0 1 1 1 0 Orf78 (ac78) TMEM154 PF15102.6 OAG37196.1 - 0.13 12.2 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 TMEM154 protein family E1-N PF14463.6 OAG37196.1 - 0.13 12.1 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 E1 N-terminal domain Miga PF10265.9 OAG37196.1 - 0.15 11.0 0.0 0.17 10.8 0.0 1.0 1 0 0 1 1 1 0 Mitoguardin Glycophorin_A PF01102.18 OAG37196.1 - 0.18 12.1 1.3 0.24 11.6 0.7 1.5 1 1 0 1 1 1 0 Glycophorin A Glyco_hydro_16 PF00722.21 OAG37197.1 - 1.7e-41 141.6 2.4 2.4e-41 141.1 2.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 ADH_N PF08240.12 OAG37198.1 - 6.6e-10 38.8 0.4 2.7e-08 33.6 0.0 2.6 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG37198.1 - 4.1e-08 33.3 0.2 7.5e-08 32.4 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAPRTase PF04095.16 OAG37199.1 - 6.3e-61 206.1 0.0 7.4e-33 114.1 0.0 3.0 2 1 1 3 3 3 2 Nicotinate phosphoribosyltransferase (NAPRTase) family NAPRTase_N PF17767.1 OAG37199.1 - 3.1e-36 124.5 0.1 5e-36 123.8 0.1 1.3 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain Syntaxin PF00804.25 OAG37200.1 - 2.4e-21 76.3 10.7 7e-21 74.8 10.7 1.7 1 1 0 1 1 1 1 Syntaxin SNARE PF05739.19 OAG37200.1 - 2.7e-11 43.3 1.9 4.6e-11 42.5 0.3 2.2 2 0 0 2 2 2 1 SNARE domain Syntaxin_2 PF14523.6 OAG37200.1 - 0.0031 17.9 4.8 0.014 15.7 0.5 2.5 2 1 0 2 2 2 1 Syntaxin-like protein DUF1634 PF07843.11 OAG37200.1 - 0.0097 16.0 0.3 0.016 15.3 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1634) HHH_2 PF12826.7 OAG37200.1 - 0.015 15.3 1.0 0.051 13.7 0.2 2.3 2 1 1 3 3 3 0 Helix-hairpin-helix motif DUF4094 PF13334.6 OAG37200.1 - 0.029 14.8 2.0 0.18 12.2 0.6 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4094) Laminin_II PF06009.12 OAG37200.1 - 0.24 11.4 7.3 1 9.4 1.5 2.5 2 1 1 3 3 3 0 Laminin Domain II Chordopox_A33R PF05966.12 OAG37200.1 - 0.74 9.1 2.7 4.3 6.6 0.6 2.2 2 0 0 2 2 2 0 Chordopoxvirus A33R protein BLOC1_2 PF10046.9 OAG37200.1 - 1.3 9.4 4.9 4.6 7.6 0.9 3.2 3 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF2116 PF09889.9 OAG37200.1 - 1.5 8.9 3.2 4.9 7.2 3.2 1.8 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) BolA PF01722.18 OAG37201.1 - 2.5e-28 98.1 0.2 3.1e-28 97.9 0.2 1.1 1 0 0 1 1 1 1 BolA-like protein Cofilin_ADF PF00241.20 OAG37201.1 - 0.04 13.7 0.0 0.05 13.4 0.0 1.3 1 0 0 1 1 1 0 Cofilin/tropomyosin-type actin-binding protein PI-PLC-X PF00388.19 OAG37202.1 - 2e-50 170.2 0.0 3.1e-50 169.5 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 OAG37202.1 - 1.1e-38 132.2 0.0 1.8e-38 131.4 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 OAG37202.1 - 0.023 15.0 0.0 0.05 13.9 0.0 1.5 1 0 0 1 1 1 0 C2 domain AMP-binding PF00501.28 OAG37203.1 - 3.8e-68 230.0 0.0 6.9e-68 229.2 0.0 1.3 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG37203.1 - 1.3e-14 54.9 0.1 2.8e-14 53.8 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain COesterase PF00135.28 OAG37204.1 - 1.2e-77 261.9 0.0 1.9e-77 261.3 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAG37204.1 - 1e-07 32.0 0.3 8.4e-07 29.1 0.3 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OAG37204.1 - 0.017 14.6 0.2 0.032 13.7 0.2 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family MFS_1 PF07690.16 OAG37205.1 - 5.5e-37 127.5 26.9 8.4e-37 126.9 26.9 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Cytochrom_B561 PF03188.16 OAG37205.1 - 0.016 15.4 8.5 0.52 10.4 0.3 3.5 4 0 0 4 4 4 0 Eukaryotic cytochrome b561 Peptidase_A8 PF01252.18 OAG37205.1 - 1.2 9.4 10.4 2 8.6 0.5 3.4 3 1 1 4 4 4 0 Signal peptidase (SPase) II peroxidase PF00141.23 OAG37207.1 - 3.6e-50 170.8 0.0 8e-50 169.7 0.0 1.6 1 0 0 1 1 1 1 Peroxidase LPD29 PF18847.1 OAG37208.1 - 0.06 14.3 0.0 0.17 12.9 0.0 1.7 1 0 0 1 1 1 0 Large polyvalent protein associated domain 29 MCM3AP_GANP PF16769.5 OAG37208.1 - 4.4 5.4 6.0 6.4 4.9 6.0 1.2 1 0 0 1 1 1 0 MCM3AP domain of GANP SurE PF01975.17 OAG37210.1 - 2.2e-34 118.9 0.0 4.1e-34 118.1 0.0 1.4 1 0 0 1 1 1 1 Survival protein SurE Fungal_trans PF04082.18 OAG37211.1 - 2.9e-07 29.8 0.4 4.9e-07 29.0 0.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain HD_4 PF13328.6 OAG37211.1 - 0.15 11.8 0.0 0.45 10.2 0.0 1.8 2 0 0 2 2 2 0 HD domain TPR_2 PF07719.17 OAG37212.1 - 4.7e-05 23.2 8.2 0.024 14.7 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 OAG37212.1 - 0.0038 17.7 1.2 0.0038 17.7 1.2 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 OAG37212.1 - 0.013 15.8 4.2 0.74 10.1 1.1 2.9 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 OAG37212.1 - 0.14 12.0 4.1 1.3 8.9 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 OAG37212.1 - 0.28 11.3 4.3 4.3 7.5 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 OAG37212.1 - 0.3 11.8 3.3 1.9 9.3 0.5 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat MFS_1 PF07690.16 OAG37213.1 - 3e-29 102.1 48.8 6.6e-15 54.9 21.4 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 OAG37213.1 - 3.5e-07 29.1 42.7 1.1e-06 27.5 16.2 3.5 1 1 2 3 3 3 3 MFS/sugar transport protein AFOR_C PF01314.18 OAG37213.1 - 0.12 11.3 0.0 0.17 10.8 0.0 1.1 1 0 0 1 1 1 0 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 Sugar_tr PF00083.24 OAG37214.1 - 3.6e-70 237.1 22.3 4.2e-70 236.8 22.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG37214.1 - 6.9e-26 91.0 18.6 6.9e-26 91.0 18.6 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_3 PF05977.13 OAG37214.1 - 0.0067 14.9 2.4 0.0088 14.5 0.4 1.9 2 0 0 2 2 2 1 Transmembrane secretion effector FMO-like PF00743.19 OAG37215.1 - 3.4e-11 42.3 0.2 1.5e-10 40.2 0.0 2.1 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OAG37215.1 - 1.6e-09 37.8 0.0 5.2e-09 36.2 0.0 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 OAG37215.1 - 4.9e-07 29.3 0.4 0.00089 18.6 0.0 3.1 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG37215.1 - 3.9e-05 23.0 1.0 0.047 12.8 0.0 3.7 3 1 1 4 4 4 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 OAG37215.1 - 0.0087 16.1 0.1 0.086 12.8 0.0 2.5 3 0 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.17 OAG37215.1 - 0.053 12.8 0.0 0.46 9.7 0.0 2.1 2 0 0 2 2 2 0 Thi4 family Shikimate_DH PF01488.20 OAG37215.1 - 0.19 11.8 0.1 1.8 8.6 0.0 2.4 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase DUF2408 PF10303.9 OAG37216.1 - 1.2e-47 161.8 6.9 3e-31 108.8 1.7 5.0 3 2 1 4 4 4 3 Protein of unknown function (DUF2408) Baculo_PEP_C PF04513.12 OAG37216.1 - 0.00071 19.6 0.5 0.012 15.7 0.1 2.8 3 1 0 3 3 3 1 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_lid_8 PF17868.1 OAG37216.1 - 0.013 15.4 0.6 0.19 11.6 0.0 3.1 3 0 0 3 3 3 0 AAA lid domain PTRF_SDPR PF15237.6 OAG37216.1 - 0.024 14.3 0.2 0.059 13.0 0.2 1.6 1 0 0 1 1 1 0 PTRF/SDPR family EzrA PF06160.12 OAG37216.1 - 0.027 12.7 2.9 0.14 10.3 0.2 2.5 2 1 0 2 2 2 0 Septation ring formation regulator, EzrA HisKA_3 PF07730.13 OAG37216.1 - 0.047 14.2 0.9 0.67 10.5 0.2 2.9 3 0 0 3 3 3 0 Histidine kinase NPV_P10 PF05531.12 OAG37216.1 - 0.065 13.7 1.2 4.9 7.7 0.0 3.7 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.12 OAG37216.1 - 0.11 12.5 1.0 0.85 9.7 0.0 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Rx_N PF18052.1 OAG37216.1 - 0.11 12.7 5.1 9.7 6.5 0.1 3.4 3 0 0 3 3 3 0 Rx N-terminal domain Wbp11 PF09429.10 OAG37216.1 - 2 8.9 5.1 8 6.9 0.2 3.0 3 0 0 3 3 3 0 WW domain binding protein 11 DUF4201 PF13870.6 OAG37216.1 - 2.5 7.8 9.0 6.3 6.5 1.8 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4201) THOC7 PF05615.13 OAG37216.1 - 3.5 7.9 7.9 5.9 7.2 0.2 2.5 2 1 0 2 2 2 0 Tho complex subunit 7 COMM_domain PF07258.14 OAG37216.1 - 4.5 7.5 8.2 11 6.2 0.2 3.6 3 0 0 3 3 3 0 COMM domain Glyco_hydro_88 PF07470.13 OAG37217.1 - 8.7e-14 51.3 0.0 1.5e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Amidohydro_3 PF07969.11 OAG37218.1 - 2.4e-31 109.7 3.5 7.9e-29 101.4 3.5 2.1 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 OAG37218.1 - 3.7e-12 46.2 3.2 1.5e-10 40.9 0.6 2.6 2 1 0 2 2 2 2 Amidohydrolase family HATPase_c PF02518.26 OAG37219.1 - 8.8e-25 87.4 0.0 1.5e-24 86.6 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 OAG37219.1 - 5.9e-19 68.3 0.1 4.4e-18 65.5 0.1 2.4 1 1 0 1 1 1 1 Response regulator receiver domain PAS_4 PF08448.10 OAG37219.1 - 1e-08 35.4 0.0 0.0016 18.7 0.0 2.9 2 0 0 2 2 2 2 PAS fold HisKA PF00512.25 OAG37219.1 - 3.4e-08 33.4 0.0 3.4e-08 33.4 0.0 1.9 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.6 OAG37219.1 - 1.5e-06 28.5 0.0 5e-06 26.9 0.0 1.9 1 0 0 1 1 1 1 GAF domain PAS_9 PF13426.7 OAG37219.1 - 1.3e-05 25.4 0.0 5.9e-05 23.3 0.0 2.2 2 1 0 2 2 1 1 PAS domain PAS_8 PF13188.7 OAG37219.1 - 7e-05 22.8 0.0 0.0002 21.3 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS_3 PF08447.12 OAG37219.1 - 7.1e-05 23.0 0.1 0.00026 21.2 0.2 1.9 2 0 0 2 2 2 1 PAS fold GAF_3 PF13492.6 OAG37219.1 - 0.00014 22.2 0.0 0.00029 21.2 0.0 1.4 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 OAG37219.1 - 0.00016 22.3 0.0 0.00057 20.5 0.0 2.0 2 0 0 2 2 1 1 GAF domain PAS PF00989.25 OAG37219.1 - 0.0025 17.8 0.0 0.0094 15.9 0.0 2.0 2 0 0 2 2 2 1 PAS fold HATPase_c_3 PF13589.6 OAG37219.1 - 0.21 11.4 0.0 0.5 10.2 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PrsW-protease PF13367.6 OAG37221.1 - 1.2e-16 60.7 12.5 1.9e-16 60.1 6.1 2.2 2 0 0 2 2 2 2 PrsW family intramembrane metalloprotease DUF1294 PF06961.13 OAG37221.1 - 0.02 15.1 0.1 0.071 13.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1294) TctB PF07331.11 OAG37221.1 - 1.1 9.5 13.7 0.22 11.8 0.9 3.2 1 1 1 2 2 2 0 Tripartite tricarboxylate transporter TctB family Rtt106 PF08512.12 OAG37222.1 - 1.2e-29 102.5 0.0 2e-29 101.8 0.0 1.4 1 0 0 1 1 1 1 Histone chaperone Rttp106-like PH_18 PF18469.1 OAG37222.1 - 1.1e-07 31.9 0.0 2.3e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain G-patch PF01585.23 OAG37223.1 - 4.5e-11 42.5 0.5 9.8e-11 41.4 0.5 1.6 1 0 0 1 1 1 1 G-patch domain RRM_1 PF00076.22 OAG37223.1 - 0.0001 22.0 0.0 0.0002 21.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AMP-binding PF00501.28 OAG37224.1 - 3.6e-90 302.6 0.0 4.5e-90 302.3 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG37224.1 - 4.9e-11 43.4 1.7 9.8e-11 42.5 0.3 2.3 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain GH3 PF03321.13 OAG37224.1 - 0.0005 19.1 0.0 0.00095 18.1 0.0 1.4 1 0 0 1 1 1 1 GH3 auxin-responsive promoter YCII PF03795.14 OAG37225.1 - 6.6e-12 45.7 0.0 8e-12 45.4 0.0 1.0 1 0 0 1 1 1 1 YCII-related domain Sod_Cu PF00080.20 OAG37226.1 - 5.1e-11 42.9 0.5 8.3e-11 42.2 0.5 1.3 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Sld5 PF05916.11 OAG37227.1 - 6.2e-13 49.2 0.0 8.6e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein FANCL_C PF11793.8 OAG37228.1 - 3.3e-07 30.4 6.9 6.8e-07 29.4 6.9 1.5 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING_2 PF13639.6 OAG37228.1 - 0.00075 19.8 11.4 0.0016 18.7 11.4 1.6 1 1 0 1 1 1 1 Ring finger domain zf-ANAPC11 PF12861.7 OAG37228.1 - 0.003 17.6 2.4 0.0066 16.5 2.4 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 OAG37228.1 - 0.0036 17.6 10.1 0.0061 16.8 10.1 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-Di19 PF05605.12 OAG37228.1 - 0.053 13.8 6.4 2.8 8.3 0.1 2.5 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding HMG_box PF00505.19 OAG37229.1 - 2.6e-10 40.6 0.4 4.4e-10 39.8 0.4 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box DUF1390 PF07150.11 OAG37231.1 - 0.069 12.9 2.0 2.7 7.6 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1390) SURF4 PF02077.15 OAG37232.1 - 2.1e-94 316.0 9.2 2.4e-94 315.9 9.2 1.0 1 0 0 1 1 1 1 SURF4 family HR_lesion PF05514.11 OAG37232.1 - 0.96 9.6 7.7 1.5 9.0 1.9 2.8 3 0 0 3 3 3 0 HR-like lesion-inducing VIT1 PF01988.19 OAG37234.1 - 0.068 13.0 0.8 1.1 9.0 0.2 2.1 2 0 0 2 2 2 0 VIT family DUF4191 PF13829.6 OAG37234.1 - 0.91 8.8 4.2 1.1 8.6 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) IU_nuc_hydro PF01156.19 OAG37236.1 - 4.4e-58 197.3 0.0 9.4e-58 196.2 0.0 1.4 1 1 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase C_LFY_FLO PF17538.2 OAG37236.1 - 0.073 12.6 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 DNA Binding Domain (C-terminal) Leafy/Floricaula GST_C_2 PF13410.6 OAG37237.1 - 7.6e-10 38.7 0.2 7.6e-10 38.7 0.2 2.3 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OAG37237.1 - 2.7e-08 33.9 0.1 4.3e-08 33.3 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OAG37237.1 - 4.6e-07 30.0 0.0 9.9e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 OAG37237.1 - 6.9e-06 26.4 0.0 1.2e-05 25.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 OAG37237.1 - 5e-05 23.6 0.0 0.00012 22.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OAG37237.1 - 0.00083 19.6 0.0 0.0017 18.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Cons_hypoth95 PF03602.15 OAG37237.1 - 0.04 13.6 0.0 0.064 12.9 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 UPF0444 PF15475.6 OAG37237.1 - 0.1 12.9 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 Transmembrane protein C12orf23, UPF0444 DUF936 PF06075.12 OAG37238.1 - 2.2 7.1 26.9 2.8 6.8 26.9 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) SET PF00856.28 OAG37239.1 - 0.021 15.2 0.0 0.028 14.8 0.0 1.3 1 0 0 1 1 1 0 SET domain EB1_binding PF05937.11 OAG37239.1 - 0.17 12.5 1.9 0.29 11.7 1.9 1.4 1 0 0 1 1 1 0 EB-1 Binding Domain Arginase PF00491.21 OAG37240.1 - 5.3e-72 242.7 0.0 6.9e-72 242.3 0.0 1.1 1 0 0 1 1 1 1 Arginase family MatE PF01554.18 OAG37241.1 - 3e-45 153.8 27.1 2.7e-25 88.9 4.2 2.2 2 0 0 2 2 2 2 MatE Fungal_trans_2 PF11951.8 OAG37242.1 - 4.8e-38 131.0 0.4 7.3e-38 130.4 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aminotran_5 PF00266.19 OAG37242.1 - 7.4e-30 104.1 0.0 1.1e-29 103.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V MFS_1 PF07690.16 OAG37243.1 - 2.2e-48 165.0 36.1 7.2e-48 163.3 30.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG37243.1 - 3.6e-14 52.5 6.9 3.6e-14 52.5 6.9 2.7 3 1 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 OAG37243.1 - 1.9e-10 39.8 1.4 3.3e-10 39.0 1.4 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) CPP1-like PF11833.8 OAG37243.1 - 1.7 8.3 3.6 18 4.9 0.0 2.9 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Aminotran_1_2 PF00155.21 OAG37244.1 - 1.6e-40 139.5 0.0 2.1e-40 139.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 OAG37244.1 - 0.0017 17.7 0.0 0.0035 16.7 0.0 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 OAG37244.1 - 0.0035 15.9 0.0 0.0062 15.1 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme MFS_1 PF07690.16 OAG37245.1 - 1.1e-16 60.7 18.5 1.8e-16 60.0 18.5 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily CBM_2 PF00553.19 OAG37245.1 - 0.024 15.0 0.8 0.052 13.9 0.8 1.5 1 0 0 1 1 1 0 Cellulose binding domain Ferric_reduct PF01794.19 OAG37246.1 - 1.4e-20 73.7 18.2 3.3e-20 72.5 18.2 1.7 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 OAG37246.1 - 2.1e-19 70.2 0.0 3.2e-19 69.6 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 OAG37246.1 - 1.1e-09 38.4 0.0 0.00088 19.3 0.0 2.4 2 0 0 2 2 2 2 FAD-binding domain Fasciclin PF02469.22 OAG37247.1 - 7e-32 110.3 0.1 1.3e-21 77.2 0.1 2.3 2 0 0 2 2 2 2 Fasciclin domain Fungal_trans PF04082.18 OAG37248.1 - 1.5e-07 30.7 0.1 3.7e-07 29.4 0.1 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Pkinase PF00069.25 OAG37249.1 - 3.4e-06 26.6 0.2 5e-06 26.1 0.0 1.3 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG37249.1 - 0.00062 19.1 0.0 0.00087 18.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase CFEM PF05730.11 OAG37250.1 - 1.7 8.8 13.5 3.2 7.9 12.4 2.1 1 1 1 2 2 2 0 CFEM domain K_channel_TID PF07941.11 OAG37252.1 - 2.7 8.5 14.7 0.65 10.5 0.8 2.1 1 1 1 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain DUF4266 PF14086.6 OAG37252.1 - 2.8 9.0 6.6 5.7 8.0 6.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4266) PCI PF01399.27 OAG37253.1 - 4.9e-21 75.2 0.0 1.7e-20 73.5 0.0 1.9 1 0 0 1 1 1 1 PCI domain RPN5_C PF18098.1 OAG37253.1 - 6.5e-13 48.6 0.2 1.6e-12 47.3 0.2 1.8 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain DUF5063 PF16702.5 OAG37253.1 - 0.11 12.9 4.2 0.21 12.0 3.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5063) ATP-sulfurylase PF01747.17 OAG37254.1 - 1.3e-85 286.2 0.1 1.9e-85 285.7 0.1 1.2 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.20 OAG37254.1 - 2.1e-55 187.0 0.0 3.3e-55 186.3 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.6 OAG37254.1 - 2.8e-52 176.6 0.0 4.3e-52 176.0 0.0 1.3 1 0 0 1 1 1 1 PUA-like domain CPT PF07931.12 OAG37254.1 - 0.15 11.9 0.0 0.55 10.1 0.0 2.0 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein PAPS_reduct PF01507.19 OAG37255.1 - 5.6e-46 156.7 0.2 1e-45 155.9 0.0 1.5 2 0 0 2 2 2 1 Phosphoadenosine phosphosulfate reductase family HAD PF12710.7 OAG37256.1 - 2.2e-21 77.1 0.0 3.4e-21 76.5 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OAG37256.1 - 7.5e-17 62.3 0.0 1e-16 61.9 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 OAG37256.1 - 9.2e-10 38.7 0.1 2.7e-09 37.2 0.0 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 OAG37256.1 - 0.013 15.5 0.0 6.4 6.8 0.0 2.8 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 OAG37256.1 - 0.018 14.5 0.0 0.096 12.1 0.0 2.0 1 1 0 1 1 1 0 Putative Phosphatase DUF705 PF05152.12 OAG37256.1 - 0.17 11.3 0.0 0.24 10.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF705) DUF4287 PF14117.6 OAG37256.1 - 0.17 12.0 0.1 0.37 11.0 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4287) SP_C-Propep PF08999.10 OAG37257.1 - 0.074 12.8 0.5 0.22 11.3 0.3 1.8 2 0 0 2 2 2 0 Surfactant protein C, N terminal propeptide SprA-related PF12118.8 OAG37257.1 - 0.23 10.6 11.8 0.51 9.4 11.8 1.5 1 0 0 1 1 1 0 SprA-related family hEGF PF12661.7 OAG37257.1 - 0.7 10.6 4.9 1.7 9.4 4.9 1.7 1 0 0 1 1 1 0 Human growth factor-like EGF EGF_2 PF07974.13 OAG37257.1 - 1.8 9.0 9.9 3.7 8.0 9.9 1.5 1 0 0 1 1 1 0 EGF-like domain TMEM154 PF15102.6 OAG37257.1 - 3 7.7 9.8 6.3 6.7 0.2 2.6 2 0 0 2 2 2 0 TMEM154 protein family ATP-synt_D PF01813.17 OAG37259.1 - 0.00082 19.2 0.1 0.0085 15.9 0.0 2.2 2 0 0 2 2 2 1 ATP synthase subunit D Complex1_LYR PF05347.15 OAG37260.1 - 6.2e-21 74.2 3.9 1.3e-20 73.2 3.9 1.6 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 OAG37260.1 - 2.2e-06 28.3 1.9 5.1e-06 27.1 1.9 1.6 1 0 0 1 1 1 1 Complex1_LYR-like DUF1761 PF08570.10 OAG37261.1 - 1.2e-26 93.4 3.1 1.3e-26 93.3 3.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1761) Methyltransf_16 PF10294.9 OAG37262.1 - 6.6e-45 153.0 0.0 9.3e-45 152.5 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 OAG37262.1 - 0.031 14.1 0.0 0.044 13.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.16 OAG37262.1 - 0.039 13.7 0.0 0.051 13.3 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein MTS PF05175.14 OAG37262.1 - 0.2 11.2 0.0 0.3 10.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain DUF2553 PF10830.8 OAG37263.1 - 0.033 15.0 0.4 0.073 13.9 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2553) Baculo_PEP_C PF04513.12 OAG37263.1 - 0.48 10.5 2.8 0.65 10.0 1.0 2.0 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus GAS PF13851.6 OAG37263.1 - 3 7.1 13.2 0.73 9.1 9.7 1.8 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding Aminotran_4 PF01063.19 OAG37264.1 - 3.5e-24 85.9 0.0 5.4e-24 85.3 0.0 1.3 1 0 0 1 1 1 1 Amino-transferase class IV Glutaredoxin PF00462.24 OAG37265.1 - 1.3e-15 57.4 0.0 3.7e-15 55.9 0.0 1.8 2 0 0 2 2 2 1 Glutaredoxin Flavoprotein PF02441.19 OAG37266.1 - 8.1e-46 155.6 0.0 9.6e-46 155.4 0.0 1.1 1 0 0 1 1 1 1 Flavoprotein UbiA PF01040.18 OAG37267.1 - 3.1e-39 134.8 10.2 3.7e-39 134.5 10.2 1.0 1 0 0 1 1 1 1 UbiA prenyltransferase family JmjC PF02373.22 OAG37268.1 - 4.4e-10 40.0 0.8 6.2e-09 36.3 0.8 2.3 1 1 0 1 1 1 1 JmjC domain, hydroxylase zf-4CXXC_R1 PF10497.9 OAG37268.1 - 2e-07 31.1 6.9 2e-07 31.1 6.9 2.6 2 0 0 2 2 2 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Cupin_2 PF07883.11 OAG37268.1 - 0.0016 18.1 0.0 0.0047 16.6 0.0 1.8 1 0 0 1 1 1 1 Cupin domain DUF1279 PF06916.13 OAG37269.1 - 3.6e-25 88.3 0.0 5.3e-25 87.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) Coa1 PF08695.10 OAG37270.1 - 7.9e-37 125.6 0.7 9.6e-37 125.3 0.0 1.4 2 0 0 2 2 2 1 Cytochrome oxidase complex assembly protein 1 Amidohydro_1 PF01979.20 OAG37271.1 - 1.4e-39 136.4 0.0 1.6e-39 136.2 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 OAG37271.1 - 5.3e-17 62.4 0.0 1.7e-10 41.0 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Fungal_trans_2 PF11951.8 OAG37272.1 - 3.5e-40 138.0 0.8 4.3e-40 137.7 0.8 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG37272.1 - 6e-09 35.9 4.6 1.5e-08 34.6 3.9 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RBD PF02196.15 OAG37273.1 - 0.11 12.6 0.3 4.9 7.3 0.0 2.9 3 0 0 3 3 3 0 Raf-like Ras-binding domain Ribosomal_L2_C PF03947.18 OAG37274.1 - 1.4e-45 154.6 1.2 1.1e-44 151.7 1.2 2.3 1 1 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Fungal_trans PF04082.18 OAG37274.1 - 1.1e-26 93.4 0.7 2e-26 92.6 0.7 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ribosomal_L2 PF00181.23 OAG37274.1 - 1.7e-25 88.8 1.0 3.1e-25 87.9 1.0 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain TPR_16 PF13432.6 OAG37275.1 - 4.5e-06 27.2 2.2 0.74 10.5 0.1 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 OAG37275.1 - 0.00022 21.5 10.5 0.17 12.2 0.0 5.2 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 OAG37275.1 - 0.00076 19.5 0.1 7.5 7.0 0.0 4.8 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 OAG37275.1 - 0.0011 18.6 0.0 1.7 8.4 0.0 3.6 3 0 0 3 3 3 1 TPR repeat TPR_2 PF07719.17 OAG37275.1 - 0.003 17.5 7.5 3.3 8.0 0.0 5.5 7 0 0 7 7 7 1 Tetratricopeptide repeat DUF5082 PF16888.5 OAG37275.1 - 0.0052 17.1 0.1 0.013 15.8 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF5082) TPR_14 PF13428.6 OAG37275.1 - 0.0069 17.1 10.5 3.1 8.8 0.0 5.3 3 2 2 5 5 5 1 Tetratricopeptide repeat Arm_APC_u3 PF16629.5 OAG37275.1 - 0.1 12.2 0.1 0.16 11.6 0.1 1.2 1 0 0 1 1 1 0 Armadillo-associated region on APC Telomere_reg-2 PF10193.9 OAG37275.1 - 0.11 13.0 0.7 17 5.9 0.1 3.0 4 0 0 4 4 4 0 Telomere length regulation protein TPR_7 PF13176.6 OAG37275.1 - 0.66 10.1 6.9 18 5.7 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat RRN3 PF05327.11 OAG37275.1 - 8.5 4.8 7.3 16 3.9 7.3 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 NmrA PF05368.13 OAG37276.1 - 6e-20 71.8 0.0 7.8e-20 71.4 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG37276.1 - 5.2e-09 36.3 0.0 1e-08 35.3 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding DUF5624 PF18538.1 OAG37276.1 - 0.00012 22.1 0.1 0.013 15.5 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF5624) Semialdhyde_dh PF01118.24 OAG37276.1 - 0.02 15.3 0.0 0.042 14.3 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 OAG37276.1 - 0.033 14.4 0.1 0.24 11.7 0.0 2.3 2 1 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_4 PF07993.12 OAG37276.1 - 0.07 12.3 0.0 0.098 11.8 0.0 1.2 1 0 0 1 1 1 0 Male sterility protein Mito_carr PF00153.27 OAG37277.1 - 1.7e-41 140.0 2.8 7.6e-17 61.0 0.1 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 OAG37277.1 - 0.11 11.7 0.4 0.66 9.1 0.1 2.0 2 0 0 2 2 2 0 Gammaproteobacterial serine protease Stomoxyn PF11585.8 OAG37277.1 - 0.36 10.9 1.7 1.1 9.3 1.7 1.8 1 0 0 1 1 1 0 Insect antimicrobial peptide, stomoxyn JAB PF01398.21 OAG37278.1 - 7.7e-10 38.8 0.2 1.5e-08 34.6 0.2 2.4 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease WLM PF08325.10 OAG37279.1 - 0.04 14.0 0.2 0.04 14.0 0.2 1.6 2 0 0 2 2 2 0 WLM domain Neugrin PF06413.11 OAG37279.1 - 0.068 13.2 2.8 0.075 13.0 2.8 1.2 1 0 0 1 1 1 0 Neugrin zf-C2H2 PF00096.26 OAG37280.1 - 7e-10 38.8 16.6 0.00015 22.1 0.3 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-met PF12874.7 OAG37280.1 - 3.9e-08 33.4 3.2 0.0054 17.1 0.2 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 OAG37280.1 - 1.4e-05 25.5 15.2 0.0051 17.5 0.3 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OAG37280.1 - 0.00027 21.1 11.1 0.022 15.0 0.5 3.0 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 OAG37280.1 - 0.0013 18.7 4.3 0.0079 16.2 0.4 2.7 2 0 0 2 2 2 1 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OAG37280.1 - 0.0046 17.3 5.7 1.6 9.3 0.0 3.7 4 0 0 4 4 4 2 Zinc-finger double domain zf_C2H2_ZHX PF18387.1 OAG37280.1 - 0.016 14.8 0.7 0.035 13.7 0.7 1.6 1 0 0 1 1 1 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-H2C2_5 PF13909.6 OAG37280.1 - 0.025 14.4 9.3 0.24 11.2 0.1 3.4 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2H2_11 PF16622.5 OAG37280.1 - 0.11 12.2 1.1 1 9.2 0.1 2.3 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_2 PF12756.7 OAG37280.1 - 0.33 11.3 6.8 21 5.5 0.2 3.0 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-MYST PF17772.1 OAG37280.1 - 1.1 8.9 6.5 0.14 11.8 1.1 2.3 3 0 0 3 3 3 0 MYST family zinc finger domain zf-TRAF PF02176.18 OAG37280.1 - 4.2 8.1 9.1 5.5 7.8 4.3 2.7 1 1 2 3 3 3 0 TRAF-type zinc finger Zn-ribbon_8 PF09723.10 OAG37280.1 - 4.2 7.6 9.6 1.8 8.7 2.5 2.9 2 1 1 3 3 3 0 Zinc ribbon domain TPR_12 PF13424.6 OAG37282.1 - 1.4e-35 121.4 8.7 1.1e-13 51.2 0.2 4.9 2 2 2 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.6 OAG37282.1 - 5.2e-29 99.3 6.3 3.8e-09 36.1 0.1 6.7 6 0 0 6 6 6 5 Tetratricopeptide repeat NACHT PF05729.12 OAG37282.1 - 1.2e-11 44.8 0.0 3.1e-11 43.5 0.0 1.7 1 0 0 1 1 1 1 NACHT domain TPR_7 PF13176.6 OAG37282.1 - 1.4e-09 37.3 5.3 0.0095 15.9 0.0 5.2 5 0 0 5 5 4 2 Tetratricopeptide repeat AAA_16 PF13191.6 OAG37282.1 - 7e-07 29.8 0.4 2.5e-06 28.0 0.0 2.2 2 0 0 2 2 1 1 AAA ATPase domain vWA-TerF-like PF10138.9 OAG37282.1 - 2.7e-06 27.6 0.0 5.4e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 vWA found in TerF C terminus TPR_MalT PF17874.1 OAG37282.1 - 4.6e-05 23.0 4.5 0.055 12.8 0.3 2.5 1 1 1 2 2 2 2 MalT-like TPR region TPR_2 PF07719.17 OAG37282.1 - 0.00017 21.4 0.4 3.8 7.9 0.0 4.7 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 OAG37282.1 - 0.00033 20.4 0.0 11 6.0 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat NB-ARC PF00931.22 OAG37282.1 - 0.00035 19.8 0.0 0.00063 19.0 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain TPR_8 PF13181.6 OAG37282.1 - 0.0044 17.1 0.4 0.75 10.2 0.2 3.7 3 1 0 3 3 3 1 Tetratricopeptide repeat AAA_22 PF13401.6 OAG37282.1 - 0.0056 17.0 0.0 0.021 15.1 0.0 2.1 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 OAG37282.1 - 0.012 16.0 0.0 0.041 14.3 0.0 2.0 1 0 0 1 1 1 0 RNA helicase AAA_19 PF13245.6 OAG37282.1 - 0.017 15.5 0.0 0.042 14.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 OAG37282.1 - 0.019 14.9 0.0 0.056 13.4 0.0 1.7 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA PF00004.29 OAG37282.1 - 0.083 13.3 0.0 0.22 11.9 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ResIII PF04851.15 OAG37282.1 - 0.1 12.6 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Rad17 PF03215.15 OAG37282.1 - 0.1 12.5 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain p47_phox_C PF08944.11 OAG37282.1 - 1.2 8.6 8.5 3.8 7.0 8.5 1.9 1 0 0 1 1 1 0 NADPH oxidase subunit p47Phox, C terminal domain PUMA PF15826.5 OAG37283.1 - 0.067 13.4 0.4 0.089 13.0 0.4 1.2 1 0 0 1 1 1 0 Bcl-2-binding component 3, p53 upregulated modulator of apoptosis PTPLA PF04387.14 OAG37284.1 - 2.2e-54 183.6 5.2 2.2e-54 183.6 5.2 1.6 2 0 0 2 2 2 1 Protein tyrosine phosphatase-like protein, PTPLA MatE PF01554.18 OAG37285.1 - 6.2e-46 156.0 26.5 4.8e-37 127.1 9.6 2.5 2 0 0 2 2 2 2 MatE Gate PF07670.14 OAG37286.1 - 0.26 11.6 6.5 0.81 10.0 3.3 2.7 2 1 0 2 2 2 0 Nucleoside recognition AA_permease_2 PF13520.6 OAG37287.1 - 1.1e-64 218.9 59.0 1.6e-64 218.4 59.0 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAG37287.1 - 6e-19 68.0 48.8 8e-19 67.6 48.8 1.1 1 0 0 1 1 1 1 Amino acid permease Gram_pos_anchor PF00746.21 OAG37287.1 - 0.71 9.9 2.5 51 3.9 0.0 2.8 2 0 0 2 2 2 0 LPXTG cell wall anchor motif RL10P_insert PF17777.1 OAG37288.1 - 1.3e-26 92.4 0.0 2.6e-26 91.4 0.0 1.5 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 OAG37288.1 - 3.4e-16 59.2 0.0 5.2e-16 58.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 Aldolase_II PF00596.21 OAG37289.1 - 2.4e-28 99.3 0.2 3e-28 99.0 0.2 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain RelA_SpoT PF04607.17 OAG37290.1 - 5.9e-12 45.9 0.1 1.1e-11 45.0 0.1 1.4 1 0 0 1 1 1 1 Region found in RelA / SpoT proteins CorA PF01544.18 OAG37291.1 - 1.7e-07 30.9 0.0 2.6e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein PXPV PF12778.7 OAG37292.1 - 0.02 14.8 13.9 0.29 11.0 0.2 3.3 2 1 0 2 2 2 0 PXPV repeat (3 copies) Sugar_tr PF00083.24 OAG37293.1 - 1.3e-83 281.4 19.6 1.5e-83 281.2 19.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG37293.1 - 5.2e-24 84.8 15.2 5.2e-24 84.8 15.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 OAG37293.1 - 4.8e-06 25.3 12.3 1.5e-05 23.6 1.0 2.3 2 1 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) GTP_EFTU PF00009.27 OAG37294.1 - 5e-59 199.1 0.0 8.1e-59 198.4 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 OAG37294.1 - 1.7e-14 53.6 0.0 4e-14 52.4 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 OAG37294.1 - 3e-08 33.6 0.0 7e-08 32.5 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 OAG37294.1 - 2.4e-07 31.0 0.0 8.3e-07 29.3 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_IV PF03764.18 OAG37294.1 - 0.0036 17.1 0.0 0.036 13.8 0.0 2.6 2 0 0 2 2 2 1 Elongation factor G, domain IV MMR_HSR1 PF01926.23 OAG37294.1 - 0.031 14.3 0.0 0.11 12.6 0.0 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase MPM1 PF17234.2 OAG37294.1 - 0.18 12.0 0.4 0.45 10.8 0.4 1.6 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 Tannase PF07519.11 OAG37295.1 - 0.18 10.7 0.0 0.31 9.9 0.0 1.3 1 0 0 1 1 1 0 Tannase and feruloyl esterase FAD_binding_3 PF01494.19 OAG37296.1 - 3.5e-15 56.1 0.6 6.1e-15 55.3 0.6 1.4 1 1 0 1 1 1 1 FAD binding domain Fibrinogen_aC PF12160.8 OAG37296.1 - 0.045 13.6 0.1 0.081 12.8 0.1 1.3 1 0 0 1 1 1 0 Fibrinogen alpha C domain 7TMR-DISMED2 PF07696.11 OAG37296.1 - 0.055 13.5 0.2 0.15 12.1 0.1 1.7 2 0 0 2 2 2 0 7TMR-DISM extracellular 2 Pyr_redox PF00070.27 OAG37296.1 - 0.17 12.5 0.0 1.2 9.7 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_23 PF13489.6 OAG37297.1 - 1e-25 90.5 0.0 1.5e-25 90.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG37297.1 - 1.5e-11 44.8 0.0 3.8e-11 43.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG37297.1 - 8e-10 39.2 0.0 1.7e-09 38.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG37297.1 - 1.7e-08 35.1 0.0 2.1e-07 31.6 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG37297.1 - 3e-08 33.6 0.0 5.2e-07 29.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 OAG37297.1 - 0.0025 17.2 0.0 0.15 11.4 0.0 2.3 2 0 0 2 2 2 1 O-methyltransferase domain Ubie_methyltran PF01209.18 OAG37297.1 - 0.0031 16.9 0.0 0.42 9.9 0.0 2.9 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.9 OAG37297.1 - 0.0075 16.0 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 OAG37297.1 - 0.0077 15.8 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 OAG37297.1 - 0.12 11.7 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) ADH_N PF08240.12 OAG37298.1 - 4.3e-21 74.9 2.7 4.9e-19 68.2 2.7 2.5 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG37298.1 - 2.8e-13 50.0 0.9 5e-13 49.2 0.5 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAG37298.1 - 6e-05 24.1 0.0 0.00012 23.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.14 OAG37298.1 - 0.01 15.4 0.1 0.018 14.6 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.18 OAG37298.1 - 0.028 14.3 2.4 0.063 13.2 0.5 2.1 1 1 1 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Glu_dehyd_C PF16912.5 OAG37298.1 - 0.029 13.8 1.9 0.054 13.0 1.9 1.4 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus 2-Hacid_dh_C PF02826.19 OAG37298.1 - 0.078 12.3 0.2 0.078 12.3 0.2 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain EXOSC1 PF10447.9 OAG37299.1 - 6.9e-18 65.3 2.8 9.8e-16 58.3 2.8 2.3 1 1 0 1 1 1 1 Exosome component EXOSC1/CSL4 ECR1_N PF14382.6 OAG37299.1 - 2.6e-10 39.9 0.3 5.7e-10 38.8 0.3 1.6 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region Arm PF00514.23 OAG37300.1 - 1.1e-76 250.8 28.8 8.7e-13 47.8 0.1 11.4 11 1 1 12 12 12 9 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 OAG37300.1 - 8.1e-20 70.9 12.2 1.6e-06 28.5 0.3 7.6 6 2 2 8 8 8 5 HEAT-like repeat HEAT_2 PF13646.6 OAG37300.1 - 3.1e-18 65.9 6.9 0.0019 18.6 0.1 7.4 4 2 2 7 7 7 5 HEAT repeats HEAT PF02985.22 OAG37300.1 - 1.2e-16 59.4 12.6 0.066 13.5 0.0 9.2 10 0 0 10 10 10 5 HEAT repeat KAP PF05804.12 OAG37300.1 - 1.4e-11 43.4 0.2 3.5e-11 42.0 0.1 1.6 1 1 1 2 2 2 1 Kinesin-associated protein (KAP) Arm_2 PF04826.13 OAG37300.1 - 9.9e-11 41.6 5.2 1.9e-05 24.3 1.0 3.0 1 1 2 3 3 3 3 Armadillo-like Adaptin_N PF01602.20 OAG37300.1 - 2.6e-10 39.5 9.7 6.5e-06 25.0 0.2 3.0 2 1 1 3 3 3 2 Adaptin N terminal region V-ATPase_H_N PF03224.14 OAG37300.1 - 3.7e-07 29.7 1.7 0.00025 20.4 1.0 3.2 2 1 1 3 3 3 2 V-ATPase subunit H Cnd1 PF12717.7 OAG37300.1 - 6.1e-06 26.4 6.9 0.027 14.5 0.2 5.1 1 1 4 6 6 6 2 non-SMC mitotic condensation complex subunit 1 DUF3361 PF11841.8 OAG37300.1 - 1.5e-05 25.0 6.2 0.85 9.5 0.5 4.3 2 1 1 3 3 3 2 Domain of unknown function (DUF3361) V-ATPase_H_C PF11698.8 OAG37300.1 - 0.00021 21.4 3.8 36 4.5 0.0 5.4 2 1 6 8 8 8 0 V-ATPase subunit H Atx10homo_assoc PF09759.9 OAG37300.1 - 0.00096 19.1 4.9 2.6 8.1 0.0 4.9 4 1 2 6 6 6 1 Spinocerebellar ataxia type 10 protein domain IFRD PF05004.13 OAG37300.1 - 0.0024 17.0 1.9 3 6.9 0.2 4.3 2 2 1 3 3 3 2 Interferon-related developmental regulator (IFRD) HEAT_PBS PF03130.16 OAG37300.1 - 0.0031 18.0 10.3 7.4 7.6 0.5 6.9 7 0 0 7 7 6 1 PBS lyase HEAT-like repeat Vac14_Fab1_bd PF12755.7 OAG37300.1 - 0.12 13.0 0.1 2.2 8.9 0.0 3.1 2 1 1 4 4 3 0 Vacuolar 14 Fab1-binding region UNC45-central PF11701.8 OAG37300.1 - 0.12 12.3 1.3 11 5.9 0.0 3.4 2 2 1 4 4 4 0 Myosin-binding striated muscle assembly central IBB PF01749.20 OAG37300.1 - 2.2 8.8 4.2 37 4.9 0.1 3.7 4 0 0 4 4 3 0 Importin beta binding domain U1snRNP70_N PF12220.8 OAG37301.1 - 2.6e-23 82.4 6.6 2.6e-23 82.4 6.6 2.3 2 1 0 2 2 2 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.22 OAG37301.1 - 1.4e-12 47.3 0.0 2.7e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OAG37301.1 - 3.7e-05 23.8 0.0 7.6e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif eRF1_1 PF03463.15 OAG37301.1 - 0.28 11.2 3.5 0.57 10.2 3.0 1.7 1 1 0 1 1 1 0 eRF1 domain 1 WD40 PF00400.32 OAG37302.1 - 6.5e-66 216.7 30.3 1.6e-10 41.3 0.2 7.2 7 0 0 7 7 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG37302.1 - 5.9e-26 90.6 5.6 0.0068 16.7 0.0 7.5 3 1 5 8 8 7 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OAG37302.1 - 6.7e-20 71.3 1.0 0.059 12.3 0.0 6.2 1 1 5 6 6 6 6 WD40 region of Ge1, enhancer of mRNA-decapping protein NACHT PF05729.12 OAG37302.1 - 5e-11 42.8 0.2 1.7e-10 41.1 0.0 2.0 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 OAG37302.1 - 2.5e-07 31.2 0.1 2.5e-07 31.2 0.1 2.8 3 1 0 3 3 3 1 AAA ATPase domain NACHT_N PF17100.5 OAG37302.1 - 3.6e-07 30.3 0.5 7.7e-07 29.2 0.2 1.6 1 1 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase WD40_like PF17005.5 OAG37302.1 - 7.1e-06 25.6 0.1 0.6 9.4 0.0 4.1 1 1 3 4 4 4 2 WD40-like domain potato_inhibit PF00280.18 OAG37302.1 - 7e-05 23.4 0.0 15 6.3 0.0 5.6 1 1 5 6 6 6 0 Potato inhibitor I family Nup160 PF11715.8 OAG37302.1 - 0.00012 20.9 20.2 3.5 6.1 0.1 6.5 2 1 5 7 7 7 6 Nucleoporin Nup120/160 AAA_22 PF13401.6 OAG37302.1 - 0.0012 19.1 0.1 0.0096 16.2 0.0 2.5 3 1 0 3 3 2 1 AAA domain DUF642 PF04862.12 OAG37302.1 - 0.0024 17.6 0.2 1.1 9.0 0.0 4.1 2 1 3 5 5 5 1 Protein of unknown function (DUF642) PD40 PF07676.12 OAG37302.1 - 0.0068 16.3 14.5 63 3.7 0.3 7.1 7 0 0 7 7 7 0 WD40-like Beta Propeller Repeat RNA_helicase PF00910.22 OAG37302.1 - 0.04 14.3 0.0 0.099 13.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA PF00004.29 OAG37302.1 - 0.069 13.6 0.0 0.23 11.9 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Gln_amidase PF15644.6 OAG37302.1 - 3.9 8.5 5.4 2.7 9.0 0.1 3.6 5 0 0 5 5 2 0 Papain fold toxin 1, glutamine deamidase FAD_binding_4 PF01565.23 OAG37303.1 - 4.5e-23 81.5 3.2 1.2e-22 80.2 3.2 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 OAG37303.1 - 3.9e-13 49.3 0.0 9e-13 48.1 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like L51_S25_CI-B8 PF05047.16 OAG37304.1 - 1.5e-08 34.4 0.1 2.2e-08 33.9 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain zf-RING_UBOX PF13445.6 OAG37305.1 - 0.00024 21.1 0.2 0.00049 20.1 0.2 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 OAG37305.1 - 0.00057 19.8 0.4 0.0012 18.8 0.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 OAG37305.1 - 0.0036 17.1 0.2 0.0071 16.2 0.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAG37305.1 - 0.0061 16.9 0.6 0.013 15.8 0.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 OAG37305.1 - 0.01 15.7 1.9 0.024 14.5 1.9 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OAG37305.1 - 0.022 14.6 2.7 0.16 11.9 3.2 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OAG37305.1 - 0.043 13.7 2.5 0.93 9.4 3.5 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Lar_restr_allev PF14354.6 OAG37305.1 - 0.15 12.4 1.7 0.35 11.3 1.7 1.6 1 0 0 1 1 1 0 Restriction alleviation protein Lar zf-C3HC4_4 PF15227.6 OAG37305.1 - 0.25 11.5 2.3 0.3 11.3 0.3 2.0 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Prp19 PF08606.11 OAG37306.1 - 1.9e-30 104.6 3.8 3.4e-30 103.8 3.8 1.4 1 0 0 1 1 1 1 Prp19/Pso4-like ANAPC4_WD40 PF12894.7 OAG37306.1 - 3.9e-16 59.1 0.0 6.3e-06 26.4 0.0 3.9 1 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OAG37306.1 - 5.8e-14 52.3 1.9 8.6e-05 23.2 0.0 4.6 4 0 0 4 4 4 3 WD domain, G-beta repeat eIF2A PF08662.11 OAG37306.1 - 8.9e-05 22.5 0.0 0.0017 18.3 0.0 2.4 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 OAG37306.1 - 0.001 18.1 0.0 0.0039 16.2 0.0 1.9 1 1 0 1 1 1 1 WD40 region of Ge1, enhancer of mRNA-decapping protein V_ATPase_I_N PF18670.1 OAG37306.1 - 0.0029 18.0 0.2 0.0075 16.7 0.2 1.7 1 0 0 1 1 1 1 V-type ATPase subunit I, N-terminal domain DUF3450 PF11932.8 OAG37306.1 - 0.0077 15.6 1.1 0.019 14.3 1.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) PQQ PF01011.21 OAG37306.1 - 0.043 13.8 0.0 0.12 12.4 0.0 1.8 1 0 0 1 1 1 0 PQQ enzyme repeat Frtz PF11768.8 OAG37306.1 - 0.097 11.0 0.0 0.89 7.8 0.0 2.2 2 1 1 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz Na_H_Exchanger PF00999.21 OAG37307.1 - 2.5e-30 105.5 26.0 5.1e-24 84.8 23.3 2.2 2 0 0 2 2 2 2 Sodium/hydrogen exchanger family RCDG1 PF15725.5 OAG37307.1 - 0.51 10.8 4.5 13 6.3 0.2 2.8 2 0 0 2 2 2 0 Renal cancer differentiation gene 1 protein AA_permease_2 PF13520.6 OAG37310.1 - 5.8e-54 183.5 45.3 7e-54 183.3 45.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAG37310.1 - 4.2e-21 75.1 41.9 9.1e-21 74.0 41.9 1.5 1 1 0 1 1 1 1 Amino acid permease Acetyltransf_1 PF00583.25 OAG37311.1 - 5.2e-12 46.0 0.0 3.2e-11 43.5 0.0 2.0 1 1 1 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OAG37311.1 - 2e-09 37.8 0.0 4.2e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OAG37311.1 - 2.4e-08 34.0 0.0 4e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 OAG37311.1 - 1.1e-06 28.8 0.0 1.5e-05 25.1 0.0 2.5 2 1 1 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 OAG37311.1 - 0.00034 20.7 0.0 0.00066 19.8 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 OAG37311.1 - 0.0015 18.5 0.0 0.0027 17.7 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein AA_permease_2 PF13520.6 OAG37313.1 - 7.5e-60 202.9 46.4 9.3e-60 202.6 46.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAG37313.1 - 7.7e-29 100.6 37.2 1e-28 100.2 37.2 1.1 1 0 0 1 1 1 1 Amino acid permease Ac76 PF05814.11 OAG37313.1 - 1.2 9.2 4.6 5.3 7.1 0.6 3.2 2 0 0 2 2 2 0 Orf76 (Ac76) NACHT PF05729.12 OAG37314.1 - 1.1e-06 28.7 0.0 4.7e-06 26.6 0.0 2.1 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 OAG37314.1 - 0.00013 22.2 0.0 0.0024 18.2 0.0 2.7 3 0 0 3 3 3 1 AAA domain DUF2075 PF09848.9 OAG37314.1 - 0.0085 15.4 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.6 OAG37314.1 - 0.011 16.2 0.0 0.042 14.2 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain Homeodomain PF00046.29 OAG37315.1 - 5.4e-18 64.6 4.8 1.2e-17 63.5 4.8 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 OAG37315.1 - 1.4e-05 24.9 1.5 4.1e-05 23.4 1.5 1.8 1 0 0 1 1 1 1 Homeobox KN domain PhoLip_ATPase_C PF16212.5 OAG37316.1 - 6.2e-60 203.0 18.8 6.2e-60 203.0 18.8 2.4 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 OAG37316.1 - 2.1e-22 78.6 0.0 5.5e-22 77.2 0.0 1.7 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 OAG37316.1 - 1.7e-14 54.7 0.2 2.4e-05 24.7 0.1 3.7 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 OAG37316.1 - 2e-10 40.6 0.0 1.3e-09 38.0 0.0 2.3 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 OAG37316.1 - 5.4e-10 39.1 0.2 2.2e-09 37.1 0.1 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 OAG37316.1 - 0.00066 19.5 0.0 0.0015 18.3 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase adh_short_C2 PF13561.6 OAG37318.1 - 8.5e-43 146.6 0.3 1.1e-42 146.3 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG37318.1 - 2.3e-34 118.6 0.3 2.9e-34 118.2 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG37318.1 - 3.6e-06 27.0 0.1 5.1e-06 26.5 0.1 1.2 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.17 OAG37318.1 - 0.0011 19.4 0.2 0.004 17.7 0.1 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Mur_ligase_C PF02875.21 OAG37318.1 - 0.03 14.6 0.1 11 6.3 0.0 2.4 2 0 0 2 2 2 0 Mur ligase family, glutamate ligase domain THF_DHG_CYH_C PF02882.19 OAG37318.1 - 0.041 13.2 0.1 0.13 11.6 0.1 1.8 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Peptidase_M16_C PF05193.21 OAG37319.1 - 1.9e-50 171.4 0.0 4.8e-50 170.1 0.0 1.7 1 1 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 OAG37319.1 - 1.7e-39 135.2 0.0 2.7e-39 134.5 0.0 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) zf-RING_11 PF17123.5 OAG37320.1 - 1.4e-12 47.1 4.8 2.6e-12 46.3 4.8 1.4 1 0 0 1 1 1 1 RING-like zinc finger FHA PF00498.26 OAG37320.1 - 7.1e-12 45.5 0.0 1.4e-11 44.5 0.0 1.6 1 0 0 1 1 1 1 FHA domain zf-RING_2 PF13639.6 OAG37320.1 - 1.3e-07 31.8 6.3 2.6e-07 30.9 6.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 OAG37320.1 - 0.00068 19.5 5.2 0.0012 18.8 5.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 OAG37320.1 - 0.0011 18.7 6.9 0.0024 17.7 6.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Yop-YscD_cpl PF16697.5 OAG37320.1 - 0.0014 18.9 0.0 0.0031 17.8 0.0 1.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain zf-C3HC4 PF00097.25 OAG37320.1 - 0.0014 18.5 6.2 0.0029 17.5 6.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 OAG37320.1 - 0.003 17.4 4.0 0.0055 16.6 4.0 1.5 1 0 0 1 1 1 1 PHD-finger zf-RING_UBOX PF13445.6 OAG37320.1 - 0.0058 16.6 6.8 0.012 15.6 6.8 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 OAG37320.1 - 0.0074 16.6 3.4 0.023 15.0 3.4 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 OAG37320.1 - 0.023 14.6 4.0 0.04 13.8 4.0 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 OAG37320.1 - 0.055 13.5 1.5 0.13 12.3 1.5 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING-like PF08746.11 OAG37320.1 - 0.48 10.8 4.2 0.93 9.9 4.2 1.5 1 0 0 1 1 1 0 RING-like domain Alb1 PF09135.11 OAG37322.1 - 2.8e-21 76.4 8.3 2.8e-21 76.4 8.3 1.9 2 0 0 2 2 2 1 Alb1 Vps16_N PF04841.13 OAG37323.1 - 7.4e-98 328.0 0.0 9.7e-98 327.6 0.0 1.1 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.12 OAG37323.1 - 7e-87 291.5 0.0 9.8e-87 291.0 0.0 1.2 1 0 0 1 1 1 1 Vps16, C-terminal region ANAPC4_WD40 PF12894.7 OAG37323.1 - 0.0016 18.7 0.0 1.6 9.1 0.0 2.6 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain lci PF12197.8 OAG37323.1 - 0.074 12.9 0.1 0.16 11.8 0.1 1.6 1 0 0 1 1 1 0 Bacillus cereus group antimicrobial protein RCC1_2 PF13540.6 OAG37323.1 - 0.074 12.9 1.6 13 5.7 0.0 3.5 4 0 0 4 4 4 0 Regulator of chromosome condensation (RCC1) repeat AAA_lid_2 PF17863.1 OAG37324.1 - 3.6e-08 33.1 1.6 3.7e-08 33.1 0.0 1.8 2 0 0 2 2 2 1 AAA lid domain Abhydrolase_3 PF07859.13 OAG37325.1 - 7.8e-52 176.2 0.0 9.9e-52 175.9 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 OAG37325.1 - 1.3e-08 34.2 0.8 2.5e-08 33.2 0.8 1.4 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 OAG37325.1 - 0.00099 18.6 0.1 0.0066 15.9 0.1 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family AXE1 PF05448.12 OAG37325.1 - 0.0034 16.1 0.5 0.016 13.9 0.1 2.0 1 1 1 2 2 2 1 Acetyl xylan esterase (AXE1) Say1_Mug180 PF10340.9 OAG37325.1 - 0.0091 14.9 0.0 0.012 14.5 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase DLH PF01738.18 OAG37325.1 - 0.011 15.3 0.0 0.051 13.1 0.0 2.0 2 0 0 2 2 2 0 Dienelactone hydrolase family Glyco_hydro_125 PF06824.11 OAG37326.1 - 5.3e-171 569.1 0.0 6.1e-171 568.9 0.0 1.0 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) CDC27 PF09507.10 OAG37327.1 - 1.1e-71 242.5 31.9 1.2e-70 239.1 31.9 1.9 1 1 0 1 1 1 1 DNA polymerase subunit Cdc27 Fungal_trans PF04082.18 OAG37328.1 - 2.8e-12 46.2 1.9 2.8e-11 43.0 0.1 2.4 2 1 0 2 2 2 2 Fungal specific transcription factor domain DUF829 PF05705.14 OAG37329.1 - 3.2e-29 102.5 0.0 1.1e-16 61.5 0.0 2.1 2 0 0 2 2 2 2 Eukaryotic protein of unknown function (DUF829) K_channel_TID PF07941.11 OAG37329.1 - 0.076 13.5 8.6 0.86 10.1 0.1 3.1 3 0 0 3 3 3 0 Potassium channel Kv1.4 tandem inactivation domain CAP_N PF01213.19 OAG37329.1 - 3.7 6.9 10.5 0.21 11.1 5.1 1.7 2 1 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal FAD_oxidored PF12831.7 OAG37330.1 - 8e-64 216.6 0.5 1.7e-62 212.2 0.5 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OAG37330.1 - 4.9e-05 22.6 1.9 9e-05 21.7 1.9 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 OAG37330.1 - 6.1e-05 23.5 0.4 0.00015 22.2 0.4 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAG37330.1 - 0.0002 20.7 0.1 0.00033 20.0 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OAG37330.1 - 0.0004 19.6 0.8 0.00065 18.9 0.8 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A DAO PF01266.24 OAG37330.1 - 0.00045 19.9 2.1 0.0009 18.9 2.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 OAG37330.1 - 0.002 17.4 0.1 0.0037 16.6 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_8 PF13450.6 OAG37330.1 - 0.0043 17.3 0.8 0.013 15.7 0.8 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DUF5329 PF17263.2 OAG37330.1 - 0.025 14.7 0.1 0.05 13.8 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5329) HI0933_like PF03486.14 OAG37330.1 - 0.043 12.5 0.3 0.066 11.9 0.3 1.2 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.17 OAG37330.1 - 0.22 10.7 0.2 0.39 9.9 0.2 1.3 1 0 0 1 1 1 0 Thi4 family Aldedh PF00171.22 OAG37331.1 - 7.6e-79 265.4 0.0 9.7e-79 265.0 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Fungal_trans PF04082.18 OAG37332.1 - 5.3e-07 28.9 0.1 5.1e-06 25.7 0.1 2.6 2 1 0 2 2 2 1 Fungal specific transcription factor domain MFS_1 PF07690.16 OAG37333.1 - 6.3e-35 120.7 30.9 6.3e-35 120.7 30.9 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 OAG37333.1 - 0.00098 18.1 5.7 0.00098 18.1 5.7 2.2 2 0 0 2 2 2 1 MFS_1 like family PetG PF02529.15 OAG37333.1 - 4.2 7.3 7.2 0.26 11.2 0.2 2.7 3 1 0 3 3 3 0 Cytochrome B6-F complex subunit 5 CMD PF02627.20 OAG37334.1 - 6.8e-12 45.3 0.0 8.8e-12 44.9 0.0 1.2 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family FAD_binding_3 PF01494.19 OAG37335.1 - 2.4e-27 96.1 0.0 5.9e-27 94.8 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 OAG37335.1 - 7.1e-05 22.2 0.0 0.00015 21.1 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG37335.1 - 0.00014 22.0 0.1 0.0028 17.8 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 OAG37335.1 - 0.00027 20.1 0.1 2.4 7.1 0.0 3.0 3 0 0 3 3 3 3 Lycopene cyclase protein SE PF08491.10 OAG37335.1 - 0.0051 15.9 0.0 0.042 12.9 0.0 2.0 2 0 0 2 2 2 1 Squalene epoxidase Pyr_redox PF00070.27 OAG37335.1 - 0.012 16.1 0.1 6.7 7.3 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG37335.1 - 0.017 14.4 0.0 0.26 10.5 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAG37335.1 - 0.02 14.0 0.1 0.031 13.4 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 OAG37335.1 - 0.12 11.0 0.0 3.6 6.2 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_3 PF13738.6 OAG37336.1 - 3.8e-12 46.1 0.1 1.5e-05 24.4 0.0 3.6 4 1 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG37336.1 - 3.4e-08 33.0 0.1 1.9e-06 27.3 0.1 3.1 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 OAG37336.1 - 3.4e-07 30.4 0.9 5.6e-07 29.7 0.0 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAG37336.1 - 6.4e-06 25.6 0.0 0.00011 21.5 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 OAG37336.1 - 4.9e-05 22.0 0.8 0.0024 16.4 0.8 2.6 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Thi4 PF01946.17 OAG37336.1 - 0.0055 16.0 0.1 0.36 10.0 0.0 2.8 3 0 0 3 3 3 1 Thi4 family NAD_binding_9 PF13454.6 OAG37336.1 - 0.0069 16.4 0.4 0.16 12.0 0.0 2.7 3 0 0 3 3 3 1 FAD-NAD(P)-binding Shikimate_DH PF01488.20 OAG37336.1 - 0.012 15.7 0.0 2.3 8.3 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 OAG37336.1 - 0.036 14.6 0.9 0.38 11.3 0.0 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase DLH PF01738.18 OAG37337.1 - 4.6e-10 39.4 0.0 3.6e-09 36.5 0.0 2.2 1 1 0 1 1 1 1 Dienelactone hydrolase family Glyco_transf_22 PF03901.17 OAG37338.1 - 1.4e-29 103.6 6.7 1.4e-29 103.6 6.7 1.4 2 0 0 2 2 2 1 Alg9-like mannosyltransferase family Med6 PF04934.14 OAG37339.1 - 2.4e-33 114.8 0.0 4.4e-33 113.9 0.0 1.4 1 0 0 1 1 1 1 MED6 mediator sub complex component UBA PF00627.31 OAG37339.1 - 1.5e-24 85.5 0.9 1.2e-13 50.6 0.1 2.5 2 0 0 2 2 2 2 UBA/TS-N domain XPC-binding PF09280.11 OAG37339.1 - 2.1e-22 78.6 12.8 3.9e-22 77.8 12.8 1.5 1 0 0 1 1 1 1 XPC-binding domain ubiquitin PF00240.23 OAG37339.1 - 1e-20 73.2 0.1 1.8e-20 72.4 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 OAG37339.1 - 1.4e-06 28.0 0.1 2.4e-06 27.3 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 OAG37339.1 - 0.0098 16.0 0.0 0.023 14.8 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 OAG37339.1 - 0.016 15.7 0.0 0.038 14.5 0.0 1.6 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain UBA_3 PF09288.10 OAG37339.1 - 0.2 11.5 0.0 4.7 7.1 0.0 2.4 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain Ubiquitin_5 PF18037.1 OAG37339.1 - 0.2 12.0 0.1 0.41 11.0 0.1 1.4 1 0 0 1 1 1 0 Ubiquitin-like domain Chorismate_bind PF00425.18 OAG37340.1 - 7e-63 212.6 0.2 2.4e-62 210.8 0.2 1.9 1 1 0 1 1 1 1 chorismate binding enzyme GATase PF00117.28 OAG37340.1 - 7.1e-27 94.4 0.0 4.5e-18 65.7 0.0 2.4 2 0 0 2 2 2 2 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.13 OAG37340.1 - 7.9e-15 55.3 0.0 2.9e-14 53.5 0.0 2.0 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.13 OAG37340.1 - 6.2e-09 35.9 0.3 0.0018 18.1 0.1 2.5 2 0 0 2 2 2 2 Peptidase C26 Methyltransf_25 PF13649.6 OAG37341.1 - 6.1e-22 78.1 0.0 1.3e-21 77.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG37341.1 - 1.2e-21 77.1 0.0 2.3e-21 76.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG37341.1 - 1.2e-19 70.6 0.0 2.6e-19 69.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG37341.1 - 3.1e-14 53.5 0.0 6.7e-14 52.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAG37341.1 - 1.3e-11 44.6 0.0 2e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAG37341.1 - 1.8e-11 43.8 0.0 3.1e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 OAG37341.1 - 2e-06 27.5 0.0 3.9e-06 26.5 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 OAG37341.1 - 0.00051 19.9 0.0 0.0008 19.2 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CheR PF01739.18 OAG37341.1 - 0.00067 19.2 0.1 0.1 12.1 0.0 2.5 1 1 1 2 2 2 1 CheR methyltransferase, SAM binding domain Methyltransf_4 PF02390.17 OAG37341.1 - 0.0015 18.1 0.0 0.019 14.4 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_32 PF13679.6 OAG37341.1 - 0.0025 17.8 0.0 0.0041 17.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 OAG37341.1 - 0.0038 16.2 0.0 0.0082 15.1 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_18 PF12847.7 OAG37341.1 - 0.0083 16.1 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 OAG37341.1 - 0.0091 15.6 0.0 0.066 12.8 0.0 2.0 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW CMAS PF02353.20 OAG37341.1 - 0.0093 15.3 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase DUF938 PF06080.12 OAG37341.1 - 0.011 15.5 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF938) PrmA PF06325.13 OAG37341.1 - 0.036 13.5 0.0 0.052 12.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) NodS PF05401.11 OAG37341.1 - 0.041 13.5 0.0 0.2 11.2 0.0 1.9 1 1 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_8 PF05148.15 OAG37341.1 - 0.053 13.4 0.0 0.34 10.7 0.0 2.0 2 0 0 2 2 2 0 Hypothetical methyltransferase Methyltr_RsmB-F PF01189.17 OAG37341.1 - 0.098 12.3 0.1 0.16 11.5 0.1 1.3 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 OAG37341.1 - 0.11 12.6 0.0 0.52 10.4 0.0 1.9 1 1 0 1 1 1 0 FtsJ-like methyltransferase DUF3684 PF12449.8 OAG37342.1 - 0 1385.3 0.0 0 1385.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) HATPase_c_3 PF13589.6 OAG37342.1 - 1.6e-05 24.7 0.0 3.4e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase WLM PF08325.10 OAG37342.1 - 0.32 11.0 2.7 0.22 11.5 0.3 1.9 2 0 0 2 2 2 0 WLM domain TRAPPC9-Trs120 PF08626.11 OAG37343.1 - 7.2e-302 1004.2 0.0 8.7e-302 1003.9 0.0 1.0 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit PAC3 PF10178.9 OAG37344.1 - 5.3e-09 36.1 0.0 7.4e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 Proteasome assembly chaperone 3 HA2 PF04408.23 OAG37345.1 - 2.9e-20 72.6 0.1 2.9e-20 72.6 0.1 3.3 3 0 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.31 OAG37345.1 - 6.2e-12 45.8 0.4 9.8e-11 42.0 0.0 3.1 4 0 0 4 4 4 1 Helicase conserved C-terminal domain DEAD PF00270.29 OAG37345.1 - 3.1e-09 36.9 0.0 6.1e-08 32.6 0.0 2.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.16 OAG37345.1 - 1.5e-07 31.7 0.0 3.1e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_19 PF13245.6 OAG37345.1 - 0.0011 19.3 0.1 0.0028 18.0 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 OAG37345.1 - 0.0019 18.5 0.0 0.0085 16.4 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 OAG37345.1 - 0.0048 16.6 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 OAG37345.1 - 0.0055 16.7 0.5 0.8 9.7 0.0 3.0 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit T2SSE PF00437.20 OAG37345.1 - 0.046 12.8 0.1 0.14 11.2 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein DUF2075 PF09848.9 OAG37345.1 - 0.049 12.9 2.2 0.055 12.7 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_23 PF13476.6 OAG37345.1 - 0.65 10.5 19.1 0.8 10.2 0.0 3.8 4 0 0 4 4 4 0 AAA domain APH PF01636.23 OAG37346.1 - 5.6e-15 55.9 0.0 7e-14 52.3 0.0 2.4 2 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 OAG37346.1 - 0.00084 19.0 0.0 0.0025 17.5 0.0 1.8 2 0 0 2 2 2 1 Choline/ethanolamine kinase DUF1679 PF07914.11 OAG37346.1 - 0.0047 15.9 0.0 0.0098 14.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) Asp PF00026.23 OAG37347.1 - 2e-06 27.4 0.7 5.9e-06 25.9 0.7 1.8 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Mid2 PF04478.12 OAG37347.1 - 0.004 17.0 0.2 0.0079 16.0 0.2 1.4 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor CusF_Ec PF11604.8 OAG37347.1 - 0.029 14.3 0.0 0.061 13.3 0.0 1.5 1 0 0 1 1 1 0 Copper binding periplasmic protein CusF Gram_pos_anchor PF00746.21 OAG37347.1 - 0.047 13.6 0.9 0.17 11.9 0.9 2.0 1 0 0 1 1 1 0 LPXTG cell wall anchor motif TMEM154 PF15102.6 OAG37347.1 - 0.1 12.5 0.0 0.28 11.1 0.0 1.7 2 0 0 2 2 2 0 TMEM154 protein family p450 PF00067.22 OAG37348.1 - 1.6e-50 172.2 0.0 4.1e-50 170.9 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 adh_short_C2 PF13561.6 OAG37349.1 - 2.1e-62 210.8 0.1 2.4e-62 210.6 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG37349.1 - 1.2e-41 142.3 0.1 1.5e-41 142.1 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG37349.1 - 5.9e-13 49.1 0.1 8.7e-13 48.6 0.1 1.2 1 0 0 1 1 1 1 KR domain Phosphodiest PF01663.22 OAG37350.1 - 3.6e-15 56.4 0.1 5.8e-15 55.7 0.1 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 OAG37350.1 - 4.6e-05 22.9 0.7 9.2e-05 21.9 0.7 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 OAG37350.1 - 0.00046 19.7 0.0 0.00081 18.9 0.0 1.5 1 0 0 1 1 1 1 Sulfatase PglZ PF08665.12 OAG37350.1 - 0.002 18.3 1.6 0.19 11.8 0.1 2.3 2 0 0 2 2 2 2 PglZ domain Gly-zipper_YMGG PF13441.6 OAG37350.1 - 1.2 9.0 6.0 2.7 7.8 6.0 1.6 1 0 0 1 1 1 0 YMGG-like Gly-zipper Gly-zipper_Omp PF13488.6 OAG37350.1 - 6.3 6.9 12.1 14 5.8 12.1 1.6 1 0 0 1 1 1 0 Glycine zipper zf-CCCH PF00642.24 OAG37351.1 - 1.9e-08 34.0 2.5 3.4e-08 33.2 2.5 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-RING_UBOX PF13445.6 OAG37351.1 - 1.4e-07 31.4 5.8 2.8e-07 30.4 5.8 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 OAG37351.1 - 7.7e-07 28.9 5.3 1.5e-06 28.0 5.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OAG37351.1 - 4.8e-06 26.3 8.2 8.9e-06 25.5 8.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAG37351.1 - 5.1e-06 26.4 8.0 9.1e-06 25.5 8.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 OAG37351.1 - 5.5e-06 26.2 9.5 1e-05 25.3 9.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf_CCCH_4 PF18345.1 OAG37351.1 - 1.8e-05 24.6 6.2 3.5e-05 23.7 6.2 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-RING_10 PF16685.5 OAG37351.1 - 2.8e-05 24.2 2.9 2.8e-05 24.2 2.9 1.7 2 0 0 2 2 1 1 zinc RING finger of MSL2 zf-RING_2 PF13639.6 OAG37351.1 - 0.00012 22.4 6.5 0.00021 21.5 6.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-CCCH_4 PF18044.1 OAG37351.1 - 0.00019 21.1 2.6 0.00019 21.1 2.6 1.7 2 0 0 2 2 1 1 CCCH-type zinc finger Prok-RING_4 PF14447.6 OAG37351.1 - 0.0064 16.3 6.1 0.012 15.4 6.1 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 DUF903 PF06004.12 OAG37351.1 - 0.015 15.2 0.3 0.062 13.2 0.0 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF903) zf-C3HC4_4 PF15227.6 OAG37351.1 - 0.032 14.4 7.9 0.077 13.2 7.9 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-CCCH_2 PF14608.6 OAG37351.1 - 0.081 13.4 3.6 0.17 12.4 3.6 1.6 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger zf-rbx1 PF12678.7 OAG37351.1 - 0.12 12.7 3.4 0.25 11.7 3.4 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain Cript PF10235.9 OAG37351.1 - 3 8.5 8.2 1.9 9.1 5.7 2.1 1 1 1 2 2 2 0 Microtubule-associated protein CRIPT CN_hydrolase PF00795.22 OAG37352.1 - 1.2e-17 64.1 0.1 6.1e-16 58.5 0.0 2.2 2 0 0 2 2 2 2 Carbon-nitrogen hydrolase HLH PF00010.26 OAG37353.1 - 9.8e-11 41.4 0.8 1.7e-10 40.7 0.8 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain TACC_C PF05010.14 OAG37353.1 - 0.033 14.0 0.3 0.044 13.6 0.3 1.1 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF724 PF05266.14 OAG37353.1 - 0.069 13.0 0.1 0.091 12.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) NleF_casp_inhib PF16809.5 OAG37353.1 - 0.069 13.1 0.2 0.12 12.3 0.2 1.4 1 0 0 1 1 1 0 NleF caspase inhibitor APG6_N PF17675.1 OAG37353.1 - 0.69 10.4 3.2 1.1 9.8 3.2 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF2235 PF09994.9 OAG37354.1 - 7.4e-75 252.0 0.0 9.8e-75 251.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) But2 PF09792.9 OAG37355.1 - 8.2e-38 130.0 0.5 1.1e-37 129.6 0.5 1.2 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain GATase_6 PF13522.6 OAG37356.1 - 1.1e-14 54.8 0.0 3.4e-14 53.2 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_7 PF13537.6 OAG37356.1 - 1.1e-12 47.9 0.0 2.8e-12 46.6 0.0 1.8 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 OAG37356.1 - 1.4e-08 34.4 0.1 2.8e-08 33.5 0.1 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.6 OAG37356.1 - 0.0043 16.0 0.0 0.015 14.2 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferases class-II PRTase_2 PF15609.6 OAG37356.1 - 0.037 13.5 0.0 0.1 12.1 0.0 1.6 1 1 0 1 1 1 0 Phosphoribosyl transferase DNA_photolyase PF00875.18 OAG37356.1 - 0.14 12.2 0.1 1.1 9.3 0.0 2.1 2 0 0 2 2 2 0 DNA photolyase DUF4733 PF15878.5 OAG37356.1 - 0.15 12.6 0.0 0.51 10.8 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4733) DNA_methylase PF00145.17 OAG37357.1 - 5.1e-42 144.4 0.1 2.4e-29 102.7 0.0 2.2 1 1 1 2 2 2 2 C-5 cytosine-specific DNA methylase WavE PF07507.11 OAG37357.1 - 0.039 13.1 0.0 0.061 12.5 0.0 1.2 1 0 0 1 1 1 0 WavE lipopolysaccharide synthesis Cons_hypoth95 PF03602.15 OAG37357.1 - 0.04 13.6 0.0 0.071 12.7 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 BAH PF01426.18 OAG37357.1 - 0.14 12.0 0.0 4.2 7.2 0.3 2.7 1 1 1 2 2 2 0 BAH domain RNase_PH PF01138.21 OAG37358.1 - 3.4e-15 56.7 0.1 1.1e-14 55.0 0.1 1.8 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 FAD_binding_3 PF01494.19 OAG37359.1 - 4.2e-71 240.0 0.0 5.9e-71 239.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 OAG37359.1 - 4.2e-46 157.0 0.1 9.2e-46 155.9 0.0 1.6 2 0 0 2 2 2 1 Phenol hydroxylase, C-terminal dimerisation domain DAO PF01266.24 OAG37359.1 - 7e-05 22.6 0.4 0.0018 17.9 0.3 2.8 1 1 1 2 2 2 1 FAD dependent oxidoreductase SE PF08491.10 OAG37359.1 - 0.0035 16.4 0.0 0.025 13.6 0.0 2.0 1 1 0 1 1 1 1 Squalene epoxidase Thi4 PF01946.17 OAG37359.1 - 0.0061 15.8 0.0 0.0093 15.2 0.0 1.2 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 OAG37359.1 - 0.0068 15.5 0.1 0.014 14.5 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 OAG37359.1 - 0.016 14.4 0.0 0.031 13.5 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG37359.1 - 0.035 14.3 0.1 0.14 12.4 0.0 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 OAG37359.1 - 0.12 11.2 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Phosphodiest PF01663.22 OAG37360.1 - 3.4e-13 49.9 1.6 2.4e-09 37.3 0.1 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 OAG37360.1 - 0.0096 15.3 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 1 Sulfatase Methyltransf_23 PF13489.6 OAG37361.1 - 9.1e-21 74.4 0.0 1.3e-20 73.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG37361.1 - 3.2e-10 40.6 0.0 8.1e-10 39.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG37361.1 - 7.8e-08 32.9 0.0 1.4e-07 32.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG37361.1 - 2.5e-07 30.6 0.0 3.2e-06 27.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG37361.1 - 1.4e-06 29.0 0.0 3.6e-06 27.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAG37361.1 - 0.0026 17.1 0.0 0.052 12.9 0.0 2.4 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 OAG37361.1 - 0.004 17.3 0.0 0.0076 16.4 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_16 PF10294.9 OAG37361.1 - 0.017 14.8 0.0 0.029 14.1 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase MTS PF05175.14 OAG37361.1 - 0.036 13.6 0.0 0.064 12.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain DUF938 PF06080.12 OAG37361.1 - 0.059 13.1 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_4 PF02390.17 OAG37361.1 - 0.099 12.1 0.0 0.26 10.8 0.0 1.6 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_2 PF00891.18 OAG37361.1 - 0.16 11.3 0.0 0.33 10.2 0.0 1.5 1 0 0 1 1 1 0 O-methyltransferase domain p450 PF00067.22 OAG37362.1 - 7.8e-67 226.0 0.0 1e-66 225.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 RAI1 PF08652.11 OAG37363.1 - 1.5e-24 85.9 0.0 4e-24 84.6 0.0 1.7 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease CEP76-C2 PF15627.6 OAG37363.1 - 0.051 13.1 0.1 0.13 11.8 0.0 1.7 2 0 0 2 2 2 0 CEP76 C2 domain IPPT PF01715.17 OAG37364.1 - 3.6e-60 203.6 0.3 5.4e-60 203.0 0.3 1.2 1 0 0 1 1 1 1 IPP transferase AAA_33 PF13671.6 OAG37364.1 - 3.9e-06 27.1 1.3 0.00023 21.3 0.1 3.2 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 OAG37364.1 - 7.8e-05 23.2 0.5 0.011 16.2 0.5 2.7 1 1 0 1 1 1 1 AAA domain IPT PF01745.16 OAG37364.1 - 0.00021 20.8 0.0 0.00035 20.0 0.0 1.4 1 0 0 1 1 1 1 Isopentenyl transferase zf-C2H2_jaz PF12171.8 OAG37364.1 - 0.00025 21.2 0.4 0.00046 20.4 0.4 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OAG37364.1 - 0.00073 19.9 0.4 0.0014 19.0 0.4 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type AAA_16 PF13191.6 OAG37364.1 - 0.0036 17.7 1.7 0.017 15.5 1.4 2.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.6 OAG37364.1 - 0.0053 17.0 0.9 0.058 13.6 0.0 2.8 2 1 1 3 3 3 1 AAA domain zf-C2H2_2 PF12756.7 OAG37364.1 - 0.011 16.0 0.1 0.022 15.1 0.1 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) AAA_22 PF13401.6 OAG37364.1 - 0.015 15.6 0.0 0.052 13.8 0.0 2.0 2 0 0 2 2 1 0 AAA domain NACHT PF05729.12 OAG37364.1 - 0.021 14.8 0.0 2.8 7.8 0.0 2.3 2 0 0 2 2 2 0 NACHT domain AAA_5 PF07728.14 OAG37364.1 - 0.034 14.2 0.0 0.081 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Hpr_kinase_C PF07475.12 OAG37364.1 - 0.049 13.2 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain AAA PF00004.29 OAG37364.1 - 0.051 14.0 0.0 0.17 12.3 0.0 1.9 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) zf-C2H2_6 PF13912.6 OAG37364.1 - 0.057 13.4 0.4 0.11 12.5 0.4 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger Ploopntkinase3 PF18751.1 OAG37364.1 - 0.063 13.2 0.8 0.41 10.5 0.0 2.4 2 1 0 2 2 2 0 P-loop Nucleotide Kinase3 RNA_helicase PF00910.22 OAG37364.1 - 0.15 12.5 0.0 0.36 11.2 0.0 1.7 1 0 0 1 1 1 0 RNA helicase PhoH PF02562.16 OAG37364.1 - 0.15 11.4 0.0 0.29 10.6 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein Torus PF16131.5 OAG37365.1 - 2.9e-43 147.0 1.8 5.5e-43 146.1 0.0 2.3 3 0 0 3 3 3 1 Torus domain RRM_1 PF00076.22 OAG37365.1 - 1.8e-07 30.9 0.0 3.7e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 OAG37365.1 - 0.00015 21.7 1.9 0.00027 20.9 1.9 1.5 1 0 0 1 1 1 1 Zinc finger domain Nup35_RRM_2 PF14605.6 OAG37365.1 - 0.011 15.7 0.0 0.021 14.8 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif zf-CCCH PF00642.24 OAG37365.1 - 0.11 12.5 2.2 0.19 11.7 2.2 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Glyco_hydro_63 PF03200.16 OAG37366.1 - 7.9e-167 555.9 0.6 1.5e-165 551.7 0.0 2.5 2 1 0 2 2 2 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 OAG37366.1 - 9.3e-81 271.2 0.0 3.7e-80 269.3 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 63 N-terminal domain Trehalase PF01204.18 OAG37366.1 - 0.055 12.3 0.0 0.098 11.5 0.0 1.3 1 0 0 1 1 1 0 Trehalase TEX33 PF15400.6 OAG37366.1 - 0.069 13.6 0.0 0.18 12.3 0.0 1.6 2 0 0 2 2 2 0 Testis-expressed sequence 33 protein family Pkinase PF00069.25 OAG37367.1 - 2.5e-69 233.6 0.0 1.6e-34 119.5 0.0 3.6 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 OAG37367.1 - 3.1e-36 125.0 0.0 7.8e-16 58.1 0.0 3.4 3 0 0 3 3 3 3 Protein tyrosine kinase HGTP_anticodon2 PF12745.7 OAG37367.1 - 1e-18 67.8 1.2 4e-17 62.6 0.0 2.4 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs tRNA-synt_His PF13393.6 OAG37367.1 - 7.8e-15 54.9 0.6 3.9e-13 49.4 0.0 2.3 2 0 0 2 2 2 1 Histidyl-tRNA synthetase RWD PF05773.22 OAG37367.1 - 7e-12 45.7 0.3 2.9e-11 43.7 0.1 2.2 2 0 0 2 2 2 1 RWD domain APH PF01636.23 OAG37367.1 - 0.00018 21.5 0.0 0.00072 19.6 0.0 2.0 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 OAG37367.1 - 0.028 13.8 0.0 0.16 11.3 0.0 2.2 2 0 0 2 2 2 0 Kinase-like DUF1682 PF07946.14 OAG37367.1 - 0.71 9.0 8.9 1.2 8.3 8.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) MMR_HSR1_Xtn PF16897.5 OAG37368.1 - 1e-34 118.7 0.9 2.5e-34 117.5 0.4 1.9 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 OAG37368.1 - 2.3e-21 75.6 0.5 4.2e-21 74.8 0.1 1.7 2 0 0 2 2 2 1 TGS domain MMR_HSR1 PF01926.23 OAG37368.1 - 3.5e-21 75.4 0.0 7.1e-21 74.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OAG37368.1 - 1.5e-13 50.6 0.0 2.5e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 OAG37368.1 - 2.9e-05 24.2 0.2 0.062 13.4 0.0 2.4 1 1 1 2 2 2 2 Dynamin family AIG1 PF04548.16 OAG37368.1 - 0.024 14.0 0.0 0.038 13.3 0.0 1.3 1 0 0 1 1 1 0 AIG1 family MeaB PF03308.16 OAG37368.1 - 0.066 12.2 0.2 0.18 10.8 0.1 1.8 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MCM PF00493.23 OAG37368.1 - 0.1 11.7 0.0 0.21 10.6 0.0 1.5 2 0 0 2 2 2 0 MCM P-loop domain AAA_18 PF13238.6 OAG37368.1 - 0.13 12.8 0.0 3.6 8.1 0.0 2.6 2 2 0 2 2 2 0 AAA domain DAO PF01266.24 OAG37369.1 - 1.5e-65 222.2 1.1 1.8e-65 221.8 1.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG37369.1 - 0.00019 20.8 0.1 0.019 14.2 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG37369.1 - 0.00078 19.6 0.6 0.002 18.3 0.6 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 OAG37369.1 - 0.0059 15.5 0.3 0.13 11.1 0.2 2.0 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox PF00070.27 OAG37369.1 - 0.0066 17.0 0.1 0.021 15.4 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OAG37369.1 - 0.018 14.1 0.0 1.3 8.0 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Mqo PF06039.15 OAG37369.1 - 0.065 11.8 0.0 3 6.3 0.0 2.0 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) MCRA PF06100.11 OAG37369.1 - 0.3 9.8 0.2 0.45 9.2 0.2 1.2 1 0 0 1 1 1 0 MCRA family CRT10 PF08728.10 OAG37370.1 - 1.6e-18 66.3 0.0 1.3e-12 46.7 0.0 2.4 2 0 0 2 2 2 2 CRT10 MMtag PF10159.9 OAG37371.1 - 5.8e-34 116.2 3.2 8.4e-34 115.7 3.2 1.2 1 0 0 1 1 1 1 Multiple myeloma tumor-associated adh_short PF00106.25 OAG37372.1 - 4.2e-16 59.0 0.0 2.2e-15 56.6 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG37372.1 - 1.7e-10 40.8 0.0 3.8e-10 39.7 0.0 1.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase CLPTM1 PF05602.12 OAG37373.1 - 8.6e-162 539.0 0.3 1.1e-161 538.7 0.3 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) Sporozoite_P67 PF05642.11 OAG37373.1 - 0.016 13.4 1.2 0.028 12.5 0.4 1.7 2 0 0 2 2 2 0 Sporozoite P67 surface antigen 2TM PF13239.6 OAG37373.1 - 0.37 11.1 2.0 2.8 8.3 0.1 2.9 2 0 0 2 2 2 0 2TM domain Mid1 PF12929.7 OAG37374.1 - 1.4e-158 528.6 0.9 1.6e-158 528.4 0.9 1.1 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.22 OAG37374.1 - 0.0042 17.7 8.0 0.21 12.2 3.7 2.8 2 1 0 2 2 2 2 Fz domain EST1_DNA_bind PF10373.9 OAG37376.1 - 3.4e-07 30.0 0.0 1.1e-06 28.4 0.0 1.9 2 0 0 2 2 2 1 Est1 DNA/RNA binding domain Spt20 PF12090.8 OAG37376.1 - 0.29 10.7 10.9 0.58 9.7 10.9 1.4 1 0 0 1 1 1 0 Spt20 family PIG-X PF08320.12 OAG37378.1 - 2.1e-64 217.3 0.0 3e-64 216.8 0.0 1.3 1 0 0 1 1 1 1 PIG-X / PBN1 SecE PF00584.20 OAG37379.1 - 0.11 12.4 0.3 0.24 11.4 0.3 1.5 1 0 0 1 1 1 0 SecE/Sec61-gamma subunits of protein translocation complex FSH1 PF03959.13 OAG37380.1 - 4.7e-26 91.8 0.0 6.6e-26 91.3 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 OAG37380.1 - 0.0092 15.8 0.1 0.026 14.3 0.1 1.8 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 OAG37380.1 - 0.01 16.4 0.0 0.027 15.1 0.0 1.6 1 1 1 2 2 2 0 Alpha/beta hydrolase family adh_short_C2 PF13561.6 OAG37381.1 - 3.1e-30 105.5 0.0 3.9e-30 105.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG37381.1 - 2.7e-24 85.7 0.0 3.5e-24 85.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG37381.1 - 1.3e-06 28.4 0.0 2.6e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OAG37381.1 - 0.0077 15.4 0.0 0.0097 15.1 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_7 PF13241.6 OAG37381.1 - 0.009 16.4 0.0 0.13 12.7 0.0 2.1 2 0 0 2 2 2 1 Putative NAD(P)-binding ADH_zinc_N PF00107.26 OAG37381.1 - 0.022 14.8 0.0 0.036 14.1 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Epimerase PF01370.21 OAG37381.1 - 0.03 13.8 0.0 0.047 13.1 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.19 OAG37381.1 - 0.06 12.7 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain WD40 PF00400.32 OAG37382.1 - 1.4e-17 63.7 6.0 0.0036 18.1 0.0 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG37382.1 - 7.8e-06 26.1 0.0 0.0025 18.1 0.0 3.3 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OAG37382.1 - 0.0019 17.2 0.3 3.7 6.4 0.1 3.6 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Peptidase_C25_C PF03785.14 OAG37382.1 - 0.018 14.9 0.0 0.05 13.4 0.0 1.7 1 0 0 1 1 1 0 Peptidase family C25, C terminal ig-like domain Roughex PF06020.11 OAG37382.1 - 4.5 6.3 4.9 6.5 5.7 4.9 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Pkinase PF00069.25 OAG37383.1 - 1.1e-67 228.2 0.8 1.2e-66 224.8 0.8 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG37383.1 - 4.9e-51 173.5 1.1 5.5e-51 173.3 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase PBD PF00786.28 OAG37383.1 - 8e-24 83.8 1.0 2.1e-23 82.4 0.1 2.3 2 0 0 2 2 2 1 P21-Rho-binding domain PH_11 PF15413.6 OAG37383.1 - 1.3e-09 38.4 0.0 4.1e-09 36.8 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain Haspin_kinase PF12330.8 OAG37383.1 - 3e-06 26.4 0.5 6.4e-06 25.4 0.5 1.6 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 OAG37383.1 - 1.3e-05 24.7 0.0 2.4e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OAG37383.1 - 6.4e-05 21.9 0.0 6.4e-05 21.9 0.0 2.2 2 1 0 2 2 1 1 Fungal protein kinase PH PF00169.29 OAG37383.1 - 0.00012 22.6 0.0 0.00031 21.2 0.0 1.7 1 0 0 1 1 1 1 PH domain KIND PF16474.5 OAG37383.1 - 0.027 14.4 0.0 0.063 13.2 0.0 1.6 1 0 0 1 1 1 0 Kinase non-catalytic C-lobe domain Seadorna_VP7 PF07387.11 OAG37383.1 - 0.034 13.2 0.1 0.058 12.4 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 OAG37383.1 - 0.087 12.7 4.8 0.6 10.0 0.3 3.0 2 1 1 3 3 3 0 Phosphotransferase enzyme family MFS_1 PF07690.16 OAG37384.1 - 6.6e-29 100.9 45.6 5.2e-28 98.0 24.6 2.5 2 1 1 3 3 3 2 Major Facilitator Superfamily LtrA PF06772.11 OAG37385.1 - 1.5e-27 96.8 10.0 2.4e-27 96.1 10.0 1.2 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) S_2TMBeta PF18153.1 OAG37385.1 - 1.2 8.9 6.2 1.2 8.9 4.0 2.1 2 0 0 2 2 2 0 SMODS-associating 2TM, beta-strand rich effector domain HTH_Tnp_1 PF01527.20 OAG37386.1 - 0.071 13.4 0.0 0.37 11.2 0.0 2.3 1 0 0 1 1 1 0 Transposase adh_short_C2 PF13561.6 OAG37387.1 - 2.4e-56 190.9 0.0 3.1e-56 190.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG37387.1 - 2.7e-48 164.0 0.1 3.3e-48 163.7 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG37387.1 - 3.1e-14 53.3 0.1 4.5e-14 52.8 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG37387.1 - 0.00027 20.5 0.0 0.00069 19.1 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 OAG37388.1 - 4.2e-31 107.9 0.0 5.8e-31 107.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG37388.1 - 1.2e-20 74.1 0.0 1.8e-20 73.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 OAG37388.1 - 0.0051 16.3 0.1 0.03 13.8 0.0 2.1 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OAG37388.1 - 0.061 12.3 0.0 0.089 11.8 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Phage_holin_2_2 PF10746.9 OAG37388.1 - 0.17 11.5 0.2 1.4 8.6 0.0 2.3 2 0 0 2 2 2 0 Phage holin T7 family, holin superfamily II tRNA_bind PF01588.20 OAG37389.1 - 6.9e-19 67.8 0.1 5e-18 65.0 0.1 2.1 1 1 0 1 1 1 1 Putative tRNA binding domain Med3 PF11593.8 OAG37389.1 - 0.3 10.2 12.9 0.44 9.7 12.9 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal SNARE PF05739.19 OAG37390.1 - 2.2e-08 34.0 0.3 4.2e-08 33.1 0.3 1.5 1 0 0 1 1 1 1 SNARE domain Use1 PF09753.9 OAG37390.1 - 0.00014 21.7 1.1 0.00021 21.1 1.1 1.3 1 0 0 1 1 1 1 Membrane fusion protein Use1 T3SSipB PF16535.5 OAG37390.1 - 0.094 13.2 0.1 0.094 13.2 0.1 2.4 2 1 0 2 2 2 0 Type III cell invasion protein SipB DUF4407 PF14362.6 OAG37390.1 - 0.76 9.1 9.8 16 4.7 9.6 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) zf-TRAF PF02176.18 OAG37391.1 - 3.7e-07 30.7 23.8 3.5e-05 24.4 6.6 3.8 2 2 2 4 4 4 3 TRAF-type zinc finger zf-C3HC4 PF00097.25 OAG37391.1 - 1.2e-06 28.3 10.2 1.2e-06 28.3 10.2 3.2 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAG37391.1 - 1.3e-06 28.3 10.6 4e-06 26.7 10.6 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 OAG37391.1 - 6.2e-06 26.3 10.8 6.2e-06 26.3 10.8 2.4 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 OAG37391.1 - 0.00026 20.9 10.5 0.00026 20.9 10.5 3.0 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 OAG37391.1 - 0.0007 19.4 9.3 0.0007 19.4 9.3 4.2 3 2 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAG37391.1 - 0.00086 19.6 10.7 0.00086 19.6 10.7 3.4 3 1 1 4 4 4 1 Ring finger domain zf-C3HC4_3 PF13920.6 OAG37391.1 - 0.0012 18.7 10.2 0.0012 18.7 10.2 2.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 OAG37391.1 - 0.022 14.5 11.4 0.14 12.0 11.4 2.4 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DNA_RNApol_7kD PF03604.13 OAG37391.1 - 0.45 10.2 3.9 2.7 7.7 2.6 2.7 1 1 1 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit DUF1664 PF07889.12 OAG37391.1 - 0.6 10.2 2.9 3 7.9 1.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) JAKMIP_CC3 PF16034.5 OAG37391.1 - 1.1 9.2 5.6 0.23 11.4 1.8 1.7 2 0 0 2 2 2 0 JAKMIP CC3 domain zf_UBZ PF18439.1 OAG37391.1 - 1.6 8.4 6.9 4.3 7.0 0.1 4.2 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger PspA_IM30 PF04012.12 OAG37391.1 - 2.3 7.8 7.4 0.11 12.1 0.4 2.1 2 1 1 3 3 3 0 PspA/IM30 family Pkip-1 PF06878.11 OAG37391.1 - 2.5 8.2 4.2 1.5 8.9 0.4 2.1 2 0 0 2 2 2 0 Pkip-1 protein Pyridox_ox_2 PF12900.7 OAG37392.1 - 1.7e-29 102.6 0.0 8.8e-29 100.3 0.0 1.9 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase YflT PF11181.8 OAG37393.1 - 0.012 16.1 0.2 0.039 14.5 0.2 1.9 1 1 0 1 1 1 0 Heat induced stress protein YflT TFIIA_gamma_C PF02751.14 OAG37394.1 - 1.1e-24 86.3 1.5 1.7e-24 85.7 1.5 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.16 OAG37394.1 - 4.9e-20 71.3 0.1 8.3e-20 70.5 0.1 1.4 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain DUF4820 PF16091.5 OAG37395.1 - 0.027 13.9 1.2 0.03 13.7 1.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) GILT PF03227.16 OAG37396.1 - 4.4e-19 68.7 0.4 9.5e-19 67.6 0.4 1.6 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) Hexokinase_1 PF00349.21 OAG37397.1 - 6e-58 196.0 0.0 7.8e-58 195.6 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.16 OAG37397.1 - 2.9e-43 148.0 0.0 5.5e-43 147.1 0.0 1.4 1 1 0 1 1 1 1 Hexokinase AAA_6 PF12774.7 OAG37400.1 - 3.3e-126 420.7 0.0 1.9e-125 418.2 0.0 2.4 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N1 PF08385.12 OAG37400.1 - 1.9e-115 386.7 7.3 1.9e-115 386.7 7.3 4.5 5 0 0 5 5 5 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 OAG37400.1 - 1.8e-103 346.8 7.7 1.8e-103 346.8 7.7 5.4 4 2 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 OAG37400.1 - 7.8e-73 244.2 0.4 7.8e-73 244.2 0.4 5.1 6 0 0 6 6 4 1 ATP-binding dynein motor region AAA_8 PF12780.7 OAG37400.1 - 2.8e-65 220.2 0.0 6.9e-65 218.9 0.0 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_7 PF12775.7 OAG37400.1 - 8.7e-41 139.4 0.0 1.9e-35 122.0 0.0 4.6 4 0 0 4 4 4 2 P-loop containing dynein motor region MT PF12777.7 OAG37400.1 - 8e-39 133.6 8.7 2.5e-38 132.0 8.7 1.9 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 OAG37400.1 - 2.2e-34 118.1 2.8 5.3e-30 104.0 0.0 4.7 4 0 0 4 4 4 2 Dynein heavy chain region D6 P-loop domain AAA_lid_11 PF18198.1 OAG37400.1 - 9.7e-29 100.3 0.0 2.8e-28 98.8 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 OAG37400.1 - 1.9e-28 99.2 0.3 2.4e-10 40.5 0.0 6.9 5 1 0 5 5 5 4 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 OAG37400.1 - 1.8e-17 63.6 0.5 3.1e-15 56.4 0.0 3.3 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA PF00004.29 OAG37400.1 - 1.4e-12 48.2 0.0 0.00077 19.9 0.0 5.0 5 0 0 5 5 4 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OAG37400.1 - 3e-11 43.8 5.6 0.062 13.6 0.0 7.2 8 0 0 8 8 5 2 AAA domain AAA_33 PF13671.6 OAG37400.1 - 5.1e-09 36.4 3.3 0.32 11.1 0.0 5.6 5 0 0 5 5 4 3 AAA domain AAA_16 PF13191.6 OAG37400.1 - 1.2e-08 35.5 7.0 1.8 8.9 0.0 8.8 9 0 0 9 9 7 1 AAA ATPase domain AAA_18 PF13238.6 OAG37400.1 - 2.9e-08 34.3 0.7 0.082 13.5 0.0 6.0 5 0 0 5 5 5 1 AAA domain AAA_lid_1 PF17857.1 OAG37400.1 - 6.2e-06 26.4 0.1 0.00053 20.2 0.0 3.5 3 0 0 3 3 3 1 AAA+ lid domain T2SSE PF00437.20 OAG37400.1 - 6.8e-06 25.3 0.0 0.055 12.5 0.0 3.5 3 0 0 3 3 3 2 Type II/IV secretion system protein ABC_tran PF00005.27 OAG37400.1 - 2.3e-05 24.9 0.1 3 8.3 0.0 5.3 4 0 0 4 4 4 1 ABC transporter AAA_29 PF13555.6 OAG37400.1 - 0.0002 21.0 0.1 0.76 9.6 0.0 3.6 3 0 0 3 3 3 1 P-loop containing region of AAA domain Mg_chelatase PF01078.21 OAG37400.1 - 0.0003 20.2 0.4 0.83 9.0 0.0 3.9 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI FtsK_SpoIIIE PF01580.18 OAG37400.1 - 0.00036 20.0 0.0 0.22 10.8 0.0 3.6 3 0 0 3 3 3 1 FtsK/SpoIIIE family BRE1 PF08647.11 OAG37400.1 - 0.00037 20.5 3.8 0.00037 20.5 3.8 4.7 3 0 0 3 3 2 1 BRE1 E3 ubiquitin ligase AAA_19 PF13245.6 OAG37400.1 - 0.00084 19.7 0.2 0.52 10.6 0.0 3.8 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.6 OAG37400.1 - 0.0015 18.1 0.0 0.22 11.1 0.0 3.3 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 OAG37400.1 - 0.0053 16.1 0.1 2.5 7.3 0.0 4.1 4 0 0 4 4 3 1 Zeta toxin IstB_IS21 PF01695.17 OAG37400.1 - 0.0059 16.4 0.2 1.1 9.0 0.0 4.1 5 0 0 5 5 4 1 IstB-like ATP binding protein AAA_24 PF13479.6 OAG37400.1 - 0.0069 16.1 0.3 24 4.5 0.0 4.2 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.6 OAG37400.1 - 0.014 15.1 3.7 37 4.0 0.0 5.3 6 0 0 6 6 5 0 AAA domain AAA_28 PF13521.6 OAG37400.1 - 0.061 13.6 0.4 5.3 7.3 0.0 3.7 3 0 0 3 3 3 0 AAA domain PduV-EutP PF10662.9 OAG37400.1 - 0.095 12.4 0.3 4.9 6.9 0.1 3.5 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation DUF4581 PF15167.6 OAG37400.1 - 0.15 12.2 0.0 0.41 10.8 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4581) TsaE PF02367.17 OAG37400.1 - 0.24 11.4 1.3 14 5.7 0.0 3.7 4 0 0 4 4 4 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE FAD-oxidase_C PF02913.19 OAG37400.1 - 3.4 7.2 7.0 0.37 10.4 0.0 3.0 3 0 0 3 3 2 0 FAD linked oxidases, C-terminal domain Sec7 PF01369.20 OAG37401.1 - 3.8e-63 212.5 0.0 5.7e-63 211.9 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 OAG37401.1 - 1.4e-19 70.5 0.0 1.7e-18 67.0 0.0 2.8 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Ribonuclease_3 PF00636.26 OAG37402.1 - 1.7e-36 125.0 0.0 5e-18 65.7 0.0 3.0 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 OAG37402.1 - 2.4e-18 66.6 0.0 2.2e-06 27.8 0.0 4.0 3 1 0 3 3 3 3 Ribonuclease-III-like Helicase_C PF00271.31 OAG37402.1 - 2e-16 60.3 0.0 5.5e-16 58.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG37402.1 - 2.3e-15 57.0 0.0 4.7e-15 56.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 OAG37402.1 - 1.1e-12 48.1 0.0 1.8e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Dicer_dimer PF03368.14 OAG37402.1 - 1.2e-11 44.6 0.0 9.3e-11 41.7 0.0 2.3 2 0 0 2 2 2 1 Dicer dimerisation domain AAA_22 PF13401.6 OAG37402.1 - 0.0056 17.0 0.0 0.026 14.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain DND1_DSRM PF14709.7 OAG37402.1 - 0.091 13.0 0.0 0.22 11.8 0.0 1.6 1 0 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 EF-hand_6 PF13405.6 OAG37403.1 - 9.8e-09 34.5 0.3 0.0012 18.6 0.1 2.8 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 OAG37403.1 - 2.8e-05 24.5 1.1 0.0031 17.9 0.0 2.4 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 OAG37403.1 - 0.0015 17.9 0.0 0.12 12.0 0.0 2.4 2 0 0 2 2 2 2 EF hand Met_10 PF02475.16 OAG37404.1 - 0.017 14.9 0.0 0.045 13.5 0.0 1.6 1 1 0 1 1 1 0 Met-10+ like-protein HTH_8 PF02954.19 OAG37404.1 - 0.29 11.0 1.1 7.2 6.5 0.1 2.4 2 0 0 2 2 2 0 Bacterial regulatory protein, Fis family Mannosyl_trans3 PF11051.8 OAG37405.1 - 3.9e-62 210.1 0.0 3e-61 207.2 0.0 2.3 1 1 0 1 1 1 1 Mannosyltransferase putative MFS_1 PF07690.16 OAG37406.1 - 3.5e-21 75.5 44.1 3.2e-14 52.6 12.8 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Dynamin_N PF00350.23 OAG37407.1 - 4.2e-17 62.7 0.0 2.5e-16 60.2 0.0 2.3 2 1 0 2 2 1 1 Dynamin family ABC_tran PF00005.27 OAG37407.1 - 4.2e-07 30.5 0.1 2.6e-06 28.0 0.0 2.4 2 0 0 2 2 1 1 ABC transporter MMR_HSR1 PF01926.23 OAG37407.1 - 6.9e-07 29.3 0.0 1.8e-05 24.8 0.0 2.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 OAG37407.1 - 0.0023 18.2 0.6 3 8.1 0.0 4.1 4 1 0 4 4 4 1 AAA domain RsgA_GTPase PF03193.16 OAG37407.1 - 0.0032 17.4 0.1 0.012 15.6 0.0 1.9 2 0 0 2 2 2 1 RsgA GTPase DUF724 PF05266.14 OAG37407.1 - 0.017 15.0 4.9 0.21 11.4 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF724) Zeta_toxin PF06414.12 OAG37407.1 - 0.026 13.8 0.2 0.14 11.4 0.1 2.1 2 0 0 2 2 2 0 Zeta toxin AAA_16 PF13191.6 OAG37407.1 - 0.047 14.1 3.8 0.15 12.4 0.0 3.5 5 0 0 5 5 4 0 AAA ATPase domain AIG1 PF04548.16 OAG37407.1 - 0.054 12.8 1.2 0.13 11.6 0.1 2.2 3 0 0 3 3 3 0 AIG1 family NB-ARC PF00931.22 OAG37407.1 - 0.059 12.5 0.2 0.61 9.2 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain AAA_29 PF13555.6 OAG37407.1 - 0.065 13.0 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF815 PF05673.13 OAG37407.1 - 0.074 12.2 0.1 0.48 9.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) C8 PF08742.11 OAG37407.1 - 0.11 12.9 0.4 0.68 10.4 0.1 2.5 2 0 0 2 2 1 0 C8 domain T2SSE PF00437.20 OAG37407.1 - 0.12 11.4 1.0 0.26 10.3 0.1 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein IIGP PF05049.13 OAG37407.1 - 0.25 10.4 2.7 0.25 10.4 0.1 2.2 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) DUF842 PF05811.13 OAG37407.1 - 0.25 11.0 8.0 4.3 7.0 0.6 3.6 3 0 0 3 3 3 0 Eukaryotic protein of unknown function (DUF842) SMC_N PF02463.19 OAG37407.1 - 0.49 9.8 0.0 0.49 9.8 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain SIMPL PF04402.14 OAG37407.1 - 0.88 10.0 7.5 0.13 12.7 0.2 3.1 4 0 0 4 4 3 0 Protein of unknown function (DUF541) Succ_DH_flav_C PF02910.20 OAG37407.1 - 1.8 8.6 11.6 0.11 12.5 1.4 3.8 5 1 0 5 5 4 0 Fumarate reductase flavoprotein C-term DUF87 PF01935.17 OAG37407.1 - 3.2 7.8 6.2 11 6.0 0.2 3.6 3 0 0 3 3 3 0 Helicase HerA, central domain DUF4140 PF13600.6 OAG37407.1 - 5.6 7.5 9.6 17 5.9 0.5 3.4 3 0 0 3 3 2 0 N-terminal domain of unknown function (DUF4140) Tektin PF03148.14 OAG37407.1 - 7.2 5.3 13.0 0.087 11.6 0.9 3.2 4 0 0 4 4 4 0 Tektin family ANAPC4_WD40 PF12894.7 OAG37408.1 - 0.0015 18.8 0.0 0.28 11.5 0.0 3.5 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OAG37408.1 - 0.0017 19.2 0.0 0.13 13.2 0.0 3.5 4 0 0 4 4 4 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 OAG37408.1 - 0.021 13.9 0.0 0.41 9.6 0.0 2.2 2 0 0 2 2 2 0 Coatomer WD associated region MMS1_N PF10433.9 OAG37408.1 - 0.09 11.4 0.0 0.56 8.8 0.0 2.1 3 0 0 3 3 3 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term Mlh1_C PF16413.5 OAG37409.1 - 1.2e-100 336.4 0.0 2.2e-100 335.5 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 OAG37409.1 - 4.3e-33 113.5 0.0 1e-32 112.3 0.0 1.7 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 OAG37409.1 - 4.2e-13 49.3 0.1 1.9e-12 47.2 0.0 2.1 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 OAG37409.1 - 6.8e-07 29.8 0.0 4.5e-06 27.1 0.0 2.4 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_pol_phi PF04931.13 OAG37409.1 - 1.5 6.8 2.9 2.5 6.1 2.9 1.2 1 0 0 1 1 1 0 DNA polymerase phi Glyco_hydro_cc PF11790.8 OAG37410.1 - 2.4e-41 141.9 1.5 3.7e-41 141.3 1.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core PilN PF05137.13 OAG37410.1 - 0.11 12.7 0.1 0.72 10.0 0.0 2.3 2 0 0 2 2 2 0 Fimbrial assembly protein (PilN) MOR2-PAG1_N PF14222.6 OAG37411.1 - 5.9e-185 616.4 0.0 9.7e-185 615.7 0.0 1.4 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.6 OAG37411.1 - 1.5e-83 280.5 0.2 1.5e-83 280.5 0.2 2.3 2 0 0 2 2 2 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.6 OAG37411.1 - 1.2e-30 106.0 18.3 4.4e-13 47.8 0.4 4.0 1 1 1 3 3 3 3 Cell morphogenesis central region FAD_binding_1 PF00667.20 OAG37412.1 - 2.3e-66 223.5 0.0 3.4e-66 223.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 OAG37412.1 - 1.8e-36 125.5 0.6 3.6e-36 124.5 0.6 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 OAG37412.1 - 2.1e-20 73.4 0.0 1.8e-19 70.4 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Kinetochor_Ybp2 PF08568.10 OAG37413.1 - 4e-69 233.7 0.1 9e-69 232.6 0.0 1.5 2 0 0 2 2 2 1 Uncharacterised protein family, YAP/Alf4/glomulin Zn_clus PF00172.18 OAG37414.1 - 2e-05 24.6 15.5 3.1e-05 24.0 15.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DEAD PF00270.29 OAG37415.1 - 9.6e-47 159.0 0.0 1.7e-46 158.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.6 OAG37415.1 - 2.2e-23 82.2 0.0 5e-23 81.1 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.31 OAG37415.1 - 2.8e-23 82.4 0.0 1.9e-22 79.7 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG37415.1 - 8.9e-09 35.6 0.0 4e-08 33.4 0.0 2.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DnaJ PF00226.31 OAG37416.1 - 2.2e-14 53.3 2.2 3.9e-14 52.5 0.4 2.4 2 0 0 2 2 2 1 DnaJ domain VIR_N PF15912.5 OAG37416.1 - 1.3 8.6 5.1 1.7 8.2 5.1 1.3 1 0 0 1 1 1 0 Virilizer, N-terminal PAPS_reduct PF01507.19 OAG37417.1 - 1.6e-18 67.4 0.1 1.5e-07 31.6 0.0 3.5 4 0 0 4 4 4 3 Phosphoadenosine phosphosulfate reductase family FANCI_S3 PF14677.6 OAG37417.1 - 0.05 13.3 0.1 0.082 12.6 0.1 1.3 1 0 0 1 1 1 0 FANCI solenoid 3 Mito_carr PF00153.27 OAG37418.1 - 4.8e-61 202.7 0.4 3.7e-21 74.9 0.0 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 OAG37418.1 - 0.046 12.9 0.0 1.3 8.2 0.0 2.4 2 0 0 2 2 2 0 Gammaproteobacterial serine protease PT-VENN PF04829.13 OAG37418.1 - 9.8 6.3 5.9 59 3.8 0.1 3.3 3 0 0 3 3 3 0 Pre-toxin domain with VENN motif Git3 PF11710.8 OAG37419.1 - 1.3e-60 204.7 19.8 2.3e-60 203.8 19.8 1.4 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 GPR_Gpa2_C PF11970.8 OAG37419.1 - 1.8e-23 82.4 3.3 1.8e-23 82.4 3.3 2.3 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term 7tm_1 PF00001.21 OAG37419.1 - 4.3e-10 39.4 0.8 6.7e-10 38.7 0.8 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF4690 PF15756.5 OAG37419.1 - 0.035 14.7 0.0 0.12 13.0 0.0 1.9 1 0 0 1 1 1 0 Small Novel Rich in Cartilage PRIMA1 PF16101.5 OAG37419.1 - 0.14 12.2 1.6 18 5.4 0.3 3.1 3 0 0 3 3 3 0 Proline-rich membrane anchor 1 Orf78 PF06024.12 OAG37419.1 - 0.21 11.9 2.3 1.4 9.3 0.0 2.8 2 0 0 2 2 2 0 Orf78 (ac78) MT-A70 PF05063.14 OAG37420.1 - 1.7e-28 99.7 0.0 3.1e-28 98.8 0.0 1.4 1 0 0 1 1 1 1 MT-A70 Peptidase_C12 PF01088.21 OAG37421.1 - 2.9e-55 187.3 0.0 3.5e-55 187.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 RsfS PF02410.15 OAG37422.1 - 7.5e-12 45.5 0.0 6.3e-11 42.6 0.0 2.1 1 1 0 1 1 1 1 Ribosomal silencing factor during starvation CC2-LZ PF16516.5 OAG37423.1 - 0.00041 20.7 9.9 0.0016 18.7 5.4 2.5 2 0 0 2 2 2 1 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator GAS PF13851.6 OAG37423.1 - 0.0012 18.2 8.0 0.0012 18.2 8.0 1.9 2 0 0 2 2 2 1 Growth-arrest specific micro-tubule binding DivIC PF04977.15 OAG37423.1 - 0.023 14.4 7.4 0.023 14.4 7.4 2.0 2 1 0 2 2 2 0 Septum formation initiator XhlA PF10779.9 OAG37423.1 - 0.025 14.8 5.2 0.087 13.0 5.2 2.0 1 0 0 1 1 1 0 Haemolysin XhlA DUF3584 PF12128.8 OAG37423.1 - 0.12 9.9 16.0 0.12 9.8 16.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) YnfE PF17452.2 OAG37423.1 - 0.14 12.5 2.7 0.37 11.1 2.4 2.0 1 1 0 1 1 1 0 Uncharacterized YnfE-like HrpB2 PF09487.10 OAG37423.1 - 0.27 11.6 5.4 0.83 10.1 3.0 2.5 2 1 0 2 2 2 0 Bacterial type III secretion protein (HrpB2) SlyX PF04102.12 OAG37423.1 - 0.66 10.6 10.9 0.39 11.4 7.0 2.5 2 1 0 2 2 2 0 SlyX DUF16 PF01519.16 OAG37423.1 - 4.8 7.7 9.4 1.5 9.4 5.8 2.0 1 1 1 2 2 2 0 Protein of unknown function DUF16 Spc7 PF08317.11 OAG37423.1 - 5.5 5.8 14.9 1.1 8.0 10.1 1.9 1 1 1 2 2 2 0 Spc7 kinetochore protein Exonuc_VII_L PF02601.15 OAG37423.1 - 5.8 6.4 11.6 7 6.1 11.1 1.6 1 1 0 1 1 1 0 Exonuclease VII, large subunit TMPIT PF07851.13 OAG37423.1 - 6.4 5.9 10.7 3.9 6.6 8.5 1.7 1 1 1 2 2 2 0 TMPIT-like protein Golgin_A5 PF09787.9 OAG37423.1 - 8.2 5.8 15.1 11 5.4 13.8 1.7 1 1 1 2 2 2 0 Golgin subfamily A member 5 TMF_DNA_bd PF12329.8 OAG37423.1 - 8.9 6.4 15.7 0.38 10.8 9.2 2.1 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding Arb2 PF09757.9 OAG37424.1 - 2.4e-85 285.8 0.7 4.2e-85 285.0 0.7 1.4 1 1 0 1 1 1 1 Arb2 domain Hist_deacetyl PF00850.19 OAG37424.1 - 8.1e-82 275.1 0.0 1.3e-81 274.5 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain B-block_TFIIIC PF04182.12 OAG37424.1 - 0.11 12.7 0.0 0.25 11.5 0.0 1.6 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC Gp_dh_C PF02800.20 OAG37425.1 - 9.4e-72 239.8 0.0 1.3e-71 239.3 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 OAG37425.1 - 1.1e-37 128.4 0.1 3.1e-37 127.0 0.1 1.8 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 OAG37425.1 - 0.052 13.7 0.1 0.18 12.0 0.0 1.9 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Pho88 PF10032.9 OAG37426.1 - 1.7e-82 275.1 0.0 1.9e-82 275.0 0.0 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) DUF4512 PF14975.6 OAG37426.1 - 0.09 13.6 0.0 0.25 12.2 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4512) DUF1368 PF07112.11 OAG37426.1 - 0.18 10.6 0.1 0.24 10.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1368) NUDIX_2 PF13869.6 OAG37427.1 - 3.2e-79 264.9 0.0 3.9e-79 264.6 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase Abhydrolase_3 PF07859.13 OAG37428.1 - 2.2e-24 86.5 0.0 4e-24 85.6 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 OAG37428.1 - 6.8e-06 25.2 0.0 1e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_M16_M PF16187.5 OAG37429.1 - 9.4e-93 310.5 1.5 1.9e-92 309.6 1.5 1.5 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16_C PF05193.21 OAG37429.1 - 1.1e-31 110.3 0.4 1.9e-19 70.4 0.0 4.1 4 0 0 4 4 4 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 OAG37429.1 - 1.5e-31 109.4 1.7 2.2e-31 108.9 0.5 2.0 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Abhydrolase_1 PF00561.20 OAG37431.1 - 5.4e-13 49.2 0.0 1.8e-12 47.4 0.0 1.8 2 1 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAG37431.1 - 2e-07 30.6 0.0 3.3e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OAG37431.1 - 5.3e-06 27.2 0.0 8.3e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family GH101_N PF17995.1 OAG37431.1 - 0.03 14.0 0.0 0.045 13.4 0.0 1.2 1 0 0 1 1 1 0 Endo-alpha-N-acetylgalactosaminidase N-terminal Abhydrolase_2 PF02230.16 OAG37431.1 - 0.035 13.9 0.0 0.23 11.2 0.0 2.0 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Ndr PF03096.14 OAG37431.1 - 0.055 12.2 0.0 0.088 11.5 0.0 1.3 1 0 0 1 1 1 0 Ndr family DUF3141 PF11339.8 OAG37431.1 - 0.076 11.4 0.0 0.4 9.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3141) adh_short PF00106.25 OAG37432.1 - 2e-18 66.6 0.0 1.9e-14 53.6 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAG37432.1 - 2.2e-10 40.5 0.0 2.1e-08 34.0 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG37432.1 - 1e-08 35.3 0.0 2.8e-08 33.9 0.0 1.8 1 1 1 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 OAG37432.1 - 0.0033 16.6 0.0 0.0046 16.1 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 OAG37432.1 - 0.069 13.4 0.0 0.38 11.0 0.0 2.2 3 0 0 3 3 3 0 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 OAG37432.1 - 0.16 12.0 0.0 0.39 10.8 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Ras PF00071.22 OAG37433.1 - 5.9e-31 107.2 0.1 7.7e-31 106.9 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAG37433.1 - 1.9e-23 82.9 0.1 3.5e-23 82.1 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAG37433.1 - 1.3e-06 28.0 0.1 1.9e-06 27.4 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OAG37433.1 - 5.1e-05 22.8 0.2 7.2e-05 22.2 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DLIC PF05783.11 OAG37433.1 - 0.00024 20.1 1.0 0.2 10.4 0.0 2.4 2 1 1 3 3 3 2 Dynein light intermediate chain (DLIC) G-alpha PF00503.20 OAG37433.1 - 0.21 10.7 2.2 0.42 9.7 0.1 2.2 1 1 1 3 3 3 0 G-protein alpha subunit Pex14_N PF04695.13 OAG37433.1 - 2.6 8.7 7.2 4.2 8.0 7.2 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF202 PF02656.15 OAG37434.1 - 5e-18 65.3 0.5 5e-18 65.3 0.5 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) TM140 PF14985.6 OAG37434.1 - 0.035 13.7 0.5 0.048 13.2 0.5 1.3 1 0 0 1 1 1 0 TM140 protein family Tetraspanin PF00335.20 OAG37434.1 - 0.049 13.3 0.8 0.18 11.5 0.7 1.8 2 0 0 2 2 2 0 Tetraspanin family ELO PF01151.18 OAG37434.1 - 0.065 12.8 1.1 0.11 12.0 0.1 1.7 1 1 0 1 1 1 0 GNS1/SUR4 family Colicin_V PF02674.16 OAG37434.1 - 0.12 12.3 5.0 0.99 9.4 5.4 1.9 1 1 1 2 2 2 0 Colicin V production protein Yip1 PF04893.17 OAG37434.1 - 0.87 9.3 6.7 0.59 9.8 2.9 2.0 1 1 1 2 2 2 0 Yip1 domain DUF2721 PF11026.8 OAG37434.1 - 2.7 7.9 9.6 5 7.0 2.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2721) MatE PF01554.18 OAG37435.1 - 1.5e-57 193.7 28.3 1.6e-34 118.9 11.4 2.3 2 0 0 2 2 2 2 MatE NUDIX PF00293.28 OAG37436.1 - 5.3e-25 88.0 0.0 8.9e-25 87.2 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain IPK PF03770.16 OAG37437.1 - 6.6e-56 189.3 0.0 1.1e-55 188.5 0.0 1.4 1 0 0 1 1 1 1 Inositol polyphosphate kinase Pam17 PF08566.10 OAG37437.1 - 0.036 13.9 0.0 0.077 12.8 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial import protein Pam17 Fungal_trans_2 PF11951.8 OAG37439.1 - 2.5e-07 29.9 1.3 6.7e-07 28.5 1.3 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG37439.1 - 7.2e-05 22.8 13.8 7.2e-05 22.8 13.8 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NOT2_3_5 PF04153.18 OAG37439.1 - 0.058 13.5 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 NOT2 / NOT3 / NOT5 family DUF1192 PF06698.11 OAG37439.1 - 0.13 12.4 0.2 0.32 11.1 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) gag-asp_proteas PF13975.6 OAG37441.1 - 0.17 12.4 0.0 0.37 11.4 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease COX15-CtaA PF02628.15 OAG37443.1 - 9.5e-102 340.4 3.8 1.5e-101 339.7 3.8 1.2 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein Fumerase PF05681.14 OAG37443.1 - 0.033 13.6 0.4 0.049 13.1 0.4 1.1 1 0 0 1 1 1 0 Fumarate hydratase (Fumerase) ETF_alpha PF00766.19 OAG37443.1 - 0.11 12.5 0.4 8.5 6.5 0.1 2.6 2 0 0 2 2 2 0 Electron transfer flavoprotein FAD-binding domain NADH-u_ox-rdase PF10785.9 OAG37443.1 - 1.2 9.8 5.1 2.6 8.8 0.2 3.3 3 1 0 3 3 3 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit KCH PF16944.5 OAG37444.1 - 1.7e-101 339.2 1.0 2e-101 339.0 1.0 1.1 1 0 0 1 1 1 1 Fungal potassium channel Virul_fac_BrkB PF03631.15 OAG37444.1 - 1.3 8.6 12.6 0.16 11.6 3.0 2.1 2 0 0 2 2 2 0 Virulence factor BrkB Oxidored_FMN PF00724.20 OAG37445.1 - 1.1e-58 199.2 0.0 1.3e-58 198.9 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family BTB PF00651.31 OAG37447.1 - 6e-08 32.9 0.0 1e-07 32.1 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain MATH PF00917.26 OAG37447.1 - 0.07 13.3 0.0 0.49 10.6 0.0 2.1 2 0 0 2 2 2 0 MATH domain DUF747 PF05346.11 OAG37448.1 - 1.8e-119 399.0 8.8 2.4e-119 398.5 8.8 1.2 1 0 0 1 1 1 1 Eukaryotic membrane protein family Caveolin PF01146.17 OAG37448.1 - 5.8 6.9 7.1 0.39 10.7 0.6 2.3 2 0 0 2 2 2 0 Caveolin tRNA-synt_2 PF00152.20 OAG37449.1 - 4.1e-78 262.6 0.3 5.7e-78 262.2 0.3 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 OAG37449.1 - 1e-11 44.7 0.0 2.7e-11 43.3 0.0 1.8 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 OAG37449.1 - 5.1e-05 22.9 0.2 0.27 10.7 0.1 2.6 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) SWIRM PF04433.17 OAG37449.1 - 0.22 11.9 0.9 1.9 8.9 0.2 2.8 3 0 0 3 3 3 0 SWIRM domain MAPEG PF01124.18 OAG37450.1 - 2.4e-24 85.7 1.9 2.8e-24 85.5 1.9 1.0 1 0 0 1 1 1 1 MAPEG family CbtB PF09489.10 OAG37450.1 - 0.36 11.0 0.1 0.36 11.0 0.1 1.8 2 0 0 2 2 2 0 Probable cobalt transporter subunit (CbtB) NTP_transferase PF00483.23 OAG37451.1 - 1.3e-31 110.1 0.0 1.9e-31 109.5 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 OAG37451.1 - 1.8e-09 36.9 4.8 4.1e-06 26.3 0.0 3.5 3 0 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 OAG37451.1 - 8.3e-08 32.7 0.0 1.2e-07 32.2 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.19 OAG37451.1 - 0.028 14.2 0.0 0.049 13.4 0.0 1.3 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase DUF2968 PF11180.8 OAG37451.1 - 0.23 11.1 0.1 0.36 10.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Pyrid_ox_like PF16242.5 OAG37452.1 - 3.7e-24 85.0 0.3 5.4e-24 84.5 0.3 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like Putative_PNPOx PF01243.20 OAG37452.1 - 3.8e-07 30.2 0.0 6.6e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase MFS_1 PF07690.16 OAG37453.1 - 3.7e-29 101.8 21.3 3.7e-29 101.8 21.3 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily SAP PF02037.27 OAG37454.1 - 9.2e-13 47.6 0.0 1.6e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 SAP domain Tho1_MOS11_C PF18592.1 OAG37454.1 - 0.0067 16.2 7.1 0.019 14.7 1.5 3.3 2 1 1 3 3 3 2 Tho1/MOS11 C-terminal domain DUF3597 PF12200.8 OAG37454.1 - 0.078 13.5 4.6 0.16 12.5 4.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3597) DUF2868 PF11067.8 OAG37454.1 - 0.41 10.1 3.3 0.53 9.7 3.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) DUF737 PF05300.11 OAG37454.1 - 1 9.7 7.0 1.6 9.1 7.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF737) DUF4551 PF15087.6 OAG37454.1 - 5.3 5.8 4.8 7.3 5.3 4.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) GFA PF04828.14 OAG37455.1 - 2.8e-08 34.0 0.0 4.5e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Methyltransf_11 PF08241.12 OAG37456.1 - 0.00084 19.9 0.0 0.0024 18.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG37456.1 - 0.008 16.9 0.0 0.018 15.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Pkinase PF00069.25 OAG37457.1 - 3.9e-75 252.6 0.0 4.5e-75 252.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG37457.1 - 1.5e-36 126.0 0.0 1.9e-36 125.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OAG37457.1 - 0.00016 20.7 0.1 0.067 12.1 0.0 2.2 2 0 0 2 2 2 2 Haspin like kinase domain APH PF01636.23 OAG37457.1 - 0.0028 17.6 0.4 0.0087 16.0 0.2 1.9 2 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 OAG37457.1 - 0.011 15.1 0.9 0.021 14.2 0.9 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OAG37457.1 - 0.062 12.6 0.3 0.16 11.3 0.1 1.8 2 1 0 2 2 2 0 Kinase-like DisA-linker PF10635.9 OAG37457.1 - 0.079 12.7 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 DisA bacterial checkpoint controller linker region Choline_kinase PF01633.20 OAG37457.1 - 0.15 11.7 0.1 0.22 11.1 0.1 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase E1_dh PF00676.20 OAG37458.1 - 3e-114 381.0 0.1 3.6e-114 380.8 0.1 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 OAG37458.1 - 0.00013 21.3 0.0 0.00019 20.7 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase DUF155 PF02582.14 OAG37459.1 - 2.5e-52 177.5 0.1 4.1e-52 176.8 0.1 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Hep_59 PF07052.11 OAG37460.1 - 0.014 16.2 2.0 0.021 15.6 0.0 2.1 2 1 0 2 2 2 0 Hepatocellular carcinoma-associated antigen 59 KOW PF00467.29 OAG37461.1 - 0.04 13.9 0.1 0.04 13.9 0.1 2.5 3 0 0 3 3 3 0 KOW motif Ribosomal_L12 PF00542.19 OAG37462.1 - 1.8e-20 73.0 3.6 1.8e-20 73.0 3.6 2.3 3 0 0 3 3 3 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 OAG37462.1 - 7.5e-11 41.6 12.3 7.5e-11 41.6 12.3 2.4 2 1 0 2 2 2 1 Ribosomal protein L7/L12 dimerisation domain Ribosomal_60s PF00428.19 OAG37462.1 - 0.026 15.1 7.1 0.026 15.1 7.1 1.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein P5CR_dimer PF14748.6 OAG37463.1 - 3e-33 114.1 3.0 3e-33 114.1 3.0 1.7 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 OAG37463.1 - 1.6e-11 44.6 0.4 1.3e-09 38.5 0.0 2.6 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent CTK3 PF12243.8 OAG37464.1 - 4.1e-40 136.6 0.0 5.8e-40 136.1 0.0 1.2 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.8 OAG37464.1 - 2.3e-16 59.7 7.4 2.3e-16 59.7 7.4 1.8 2 0 0 2 2 2 1 CTD kinase subunit gamma CTK3 C-terminus Hat1_N PF10394.9 OAG37465.1 - 8.5e-45 152.9 0.0 1.4e-44 152.1 0.0 1.4 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus DUF485 PF04341.12 OAG37466.1 - 3.5 7.6 6.7 0.86 9.6 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function, DUF485 Zip PF02535.22 OAG37467.1 - 5.4e-36 124.5 19.5 1.6e-27 96.7 11.6 3.0 2 1 0 2 2 2 2 ZIP Zinc transporter DUF3899 PF13038.6 OAG37467.1 - 0.03 14.8 0.4 16 6.1 0.0 4.2 4 0 0 4 4 4 0 Domain of unknown function (DUF3899) PDR_assoc PF08370.11 OAG37467.1 - 0.064 13.0 0.4 0.27 11.0 0.0 2.2 2 0 0 2 2 2 0 Plant PDR ABC transporter associated DUF4395 PF14340.6 OAG37467.1 - 0.91 9.9 6.8 1.3 9.3 0.0 3.7 4 1 1 5 5 5 0 Domain of unknown function (DUF4395) WD40 PF00400.32 OAG37468.1 - 1.4e-38 130.2 23.7 5.4e-07 30.2 0.1 7.8 8 0 0 8 8 8 6 WD domain, G-beta repeat F-box-like PF12937.7 OAG37468.1 - 4.8e-12 45.6 0.8 9.9e-12 44.6 0.8 1.6 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 OAG37468.1 - 2.4e-09 37.4 1.5 0.072 13.4 0.0 5.5 1 1 6 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OAG37468.1 - 1e-07 31.0 6.5 0.38 9.3 0.5 5.8 1 1 5 6 6 6 4 Nucleoporin Nup120/160 WD40_like PF17005.5 OAG37468.1 - 1.2e-06 28.1 0.0 0.037 13.4 0.0 2.9 1 1 1 3 3 3 2 WD40-like domain F-box PF00646.33 OAG37468.1 - 0.00013 21.7 1.4 0.00033 20.5 1.4 1.8 1 0 0 1 1 1 1 F-box domain F-box_5 PF18511.1 OAG37468.1 - 0.015 14.9 0.1 0.036 13.6 0.1 1.7 1 0 0 1 1 1 0 F-box PQQ_2 PF13360.6 OAG37468.1 - 0.047 13.3 3.3 0.11 12.0 1.2 2.5 1 1 0 2 2 2 0 PQQ-like domain Mito_carr PF00153.27 OAG37469.1 - 1.6e-48 162.6 1.9 1.5e-16 60.1 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Fungal_trans PF04082.18 OAG37470.1 - 5.4e-09 35.5 0.8 4.9e-08 32.3 0.1 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain ABM PF03992.16 OAG37471.1 - 0.0072 16.4 0.3 0.2 11.8 0.1 2.8 2 1 0 2 2 2 1 Antibiotic biosynthesis monooxygenase VWA_2 PF13519.6 OAG37471.1 - 0.06 14.0 0.2 0.3 11.8 0.1 2.1 1 1 1 2 2 2 0 von Willebrand factor type A domain DUF1996 PF09362.10 OAG37472.1 - 2.3e-61 207.8 1.9 2.3e-61 207.8 1.9 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1996) Fibrinogen_C PF00147.18 OAG37472.1 - 0.089 12.6 0.2 0.17 11.7 0.2 1.4 1 0 0 1 1 1 0 Fibrinogen beta and gamma chains, C-terminal globular domain Homeobox_KN PF05920.11 OAG37474.1 - 4.3e-12 45.7 0.1 9.6e-12 44.6 0.1 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 OAG37474.1 - 0.0013 18.5 0.0 0.0026 17.6 0.0 1.5 1 0 0 1 1 1 1 Homeodomain Totivirus_coat PF05518.11 OAG37474.1 - 0.36 8.8 1.7 0.49 8.4 1.7 1.1 1 0 0 1 1 1 0 Totivirus coat protein FAD_binding_1 PF00667.20 OAG37475.1 - 3.6e-46 157.5 0.0 5.2e-46 157.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 OAG37475.1 - 5.7e-09 36.6 0.0 1.5e-08 35.2 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain GrpB PF04229.14 OAG37476.1 - 1.3e-48 165.2 0.0 1.6e-48 165.0 0.0 1.0 1 0 0 1 1 1 1 GrpB protein Goodbye PF17109.5 OAG37477.1 - 1.8e-05 25.2 0.0 0.00022 21.7 0.0 2.7 3 0 0 3 3 3 1 fungal STAND N-terminal Goodbye domain NACHT_N PF17100.5 OAG37477.1 - 0.0068 16.3 4.4 0.09 12.6 0.1 3.0 2 1 0 2 2 2 1 N-terminal domain of NWD NACHT-NTPase Xpo1 PF08389.12 OAG37477.1 - 0.036 14.1 1.3 0.1 12.6 1.3 1.7 1 0 0 1 1 1 0 Exportin 1-like protein TPR_14 PF13428.6 OAG37477.1 - 0.14 13.0 2.0 0.6 11.1 0.2 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 OAG37477.1 - 0.22 11.7 1.2 0.59 10.3 0.4 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 OAG37477.1 - 0.6 10.4 2.4 0.63 10.3 0.2 2.3 3 0 0 3 3 3 0 Tetratricopeptide repeat AAA PF00004.29 OAG37479.1 - 5.5e-17 62.4 0.0 9.1e-17 61.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OAG37479.1 - 7.1e-05 23.1 0.8 0.00031 21.0 0.1 2.2 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 OAG37479.1 - 0.0027 18.1 0.0 0.007 16.8 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 OAG37479.1 - 0.0038 17.2 0.0 0.0083 16.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 OAG37479.1 - 0.062 13.0 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 OAG37479.1 - 0.069 12.8 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_33 PF13671.6 OAG37479.1 - 0.14 12.3 0.1 0.38 10.9 0.1 1.8 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 OAG37479.1 - 0.16 11.8 0.0 0.92 9.4 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Fungal_trans PF04082.18 OAG37480.1 - 1.2e-15 57.2 0.1 1.6e-15 56.9 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain NAD_binding_10 PF13460.6 OAG37482.1 - 2.7e-10 40.5 1.1 3.8e-08 33.4 0.4 3.5 2 1 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 OAG37482.1 - 4.8e-06 26.2 0.0 7.2e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 OAG37482.1 - 1.1e-05 24.7 0.0 1.7e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 OAG37482.1 - 0.00017 20.9 0.0 0.00026 20.2 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 OAG37482.1 - 0.0094 15.4 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Semialdhyde_dh PF01118.24 OAG37482.1 - 0.015 15.8 0.0 0.035 14.5 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Med20 PF08612.11 OAG37483.1 - 5.6e-22 78.2 0.0 6e-22 78.1 0.0 1.1 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex Glyco_hydro_47 PF01532.20 OAG37484.1 - 8.8e-184 611.7 0.0 1.2e-183 611.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_127 PF07944.12 OAG37484.1 - 0.0074 14.8 0.0 0.18 10.3 0.0 2.1 2 0 0 2 2 2 2 Beta-L-arabinofuranosidase, GH127 CbtB PF09489.10 OAG37484.1 - 0.037 14.1 1.1 0.27 11.4 0.5 2.3 2 0 0 2 2 2 0 Probable cobalt transporter subunit (CbtB) CTD_bind PF04818.13 OAG37485.1 - 1.6e-19 70.5 0.0 3.7e-19 69.3 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase II-binding domain. CREPT PF16566.5 OAG37485.1 - 0.061 13.5 0.7 0.12 12.5 0.7 1.5 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour Clathrin_lg_ch PF01086.17 OAG37486.1 - 9.5e-70 235.2 4.8 1.1e-69 235.1 4.8 1.0 1 0 0 1 1 1 1 Clathrin light chain CdiI_2 PF18593.1 OAG37487.1 - 0.031 14.9 0.1 1.4 9.6 0.0 2.8 2 0 0 2 2 2 0 CdiI immunity protein RCDG1 PF15725.5 OAG37487.1 - 0.074 13.5 2.6 0.43 11.0 2.6 2.4 1 0 0 1 1 1 0 Renal cancer differentiation gene 1 protein NYD-SP28_assoc PF14775.6 OAG37487.1 - 0.14 12.2 5.8 0.18 11.9 0.7 3.3 3 0 0 3 3 3 0 Sperm tail C-terminal domain CAP_N PF01213.19 OAG37487.1 - 1 8.8 8.8 1.9 7.9 7.0 2.4 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal DUF4936 PF16290.5 OAG37487.1 - 2.6 8.8 5.7 7 7.4 0.1 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4936) ATG16 PF08614.11 OAG37487.1 - 9.5 6.4 19.6 1.1 9.5 3.4 3.8 3 2 0 3 3 3 0 Autophagy protein 16 (ATG16) Ank PF00023.30 OAG37488.1 - 0.032 14.7 0.0 0.1 13.1 0.0 1.9 2 0 0 2 2 2 0 Ankyrin repeat adh_short PF00106.25 OAG37489.1 - 4.1e-50 170.0 0.9 4.9e-50 169.7 0.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG37489.1 - 7.2e-48 163.2 1.5 1.1e-47 162.5 1.5 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG37489.1 - 3.2e-09 36.9 0.6 5.7e-09 36.1 0.6 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG37489.1 - 0.00043 19.8 0.2 0.0015 18.1 0.2 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family VBS PF08913.10 OAG37489.1 - 0.036 14.5 0.1 0.063 13.7 0.1 1.4 1 0 0 1 1 1 0 Vinculin Binding Site Indigoidine_A PF04227.12 OAG37490.1 - 2.4e-119 398.0 0.1 4.1e-119 397.3 0.1 1.4 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.24 OAG37490.1 - 1.4e-21 77.1 0.1 3.8e-12 46.1 0.1 2.7 3 0 0 3 3 3 2 pfkB family carbohydrate kinase DFP PF04127.15 OAG37490.1 - 0.19 11.6 1.1 1 9.2 1.1 2.1 2 1 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein SnoaL_2 PF12680.7 OAG37491.1 - 9.5e-10 39.0 0.2 3.3e-09 37.3 0.2 2.0 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 OAG37491.1 - 1.1e-05 25.2 0.1 2.3e-05 24.2 0.1 1.5 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase DUF3328 PF11807.8 OAG37494.1 - 3e-53 180.8 0.0 3.8e-53 180.5 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) SIS PF01380.22 OAG37495.1 - 5.1e-11 42.5 0.1 3.7e-10 39.8 0.0 2.0 2 0 0 2 2 2 1 SIS domain zf-C2H2_jaz PF12171.8 OAG37496.1 - 7.9e-05 22.8 0.0 0.00012 22.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding OrsD PF12013.8 OAG37496.1 - 0.00053 20.4 0.4 0.0015 19.0 0.0 2.0 2 0 0 2 2 2 1 Orsellinic acid/F9775 biosynthesis cluster protein D zf-met PF12874.7 OAG37496.1 - 0.00077 19.8 0.2 0.0012 19.1 0.2 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 OAG37496.1 - 0.03 14.6 0.2 0.078 13.3 0.2 1.6 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Fzo_mitofusin PF04799.13 OAG37496.1 - 0.31 10.6 1.5 0.59 9.7 1.5 1.4 1 0 0 1 1 1 0 fzo-like conserved region ASD2 PF08687.11 OAG37496.1 - 1.6 8.2 12.2 0.2 11.2 7.1 1.9 1 1 1 2 2 2 0 Apx/Shroom domain ASD2 DASH_Spc19 PF08287.11 OAG37496.1 - 6.9 6.5 12.5 0.08 12.8 2.6 2.4 2 1 0 2 2 2 0 Spc19 SPOC PF07744.13 OAG37497.1 - 1.9e-19 70.1 0.0 3.8e-19 69.1 0.0 1.5 1 0 0 1 1 1 1 SPOC domain TFIIS_M PF07500.14 OAG37497.1 - 3.6e-19 69.3 0.1 6e-19 68.6 0.1 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain PHD PF00628.29 OAG37497.1 - 5.7e-09 35.7 11.9 1.1e-08 34.8 11.9 1.5 1 0 0 1 1 1 1 PHD-finger zinc_ribbon_10 PF10058.9 OAG37497.1 - 0.024 14.4 6.9 0.049 13.4 6.9 1.5 1 0 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein PHD_2 PF13831.6 OAG37497.1 - 0.42 10.2 6.4 0.83 9.3 6.4 1.5 1 0 0 1 1 1 0 PHD-finger NAD_binding_2 PF03446.15 OAG37497.1 - 0.59 10.3 2.4 0.42 10.8 0.5 1.7 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase WW PF00397.26 OAG37498.1 - 1.4e-13 50.6 4.3 1.6e-09 37.7 3.8 2.6 2 0 0 2 2 2 2 WW domain FF PF01846.19 OAG37498.1 - 8.4e-12 45.1 5.9 6.7e-10 39.0 0.0 2.7 2 0 0 2 2 2 2 FF domain Proteasome PF00227.26 OAG37499.1 - 7.9e-61 204.9 0.1 9.7e-61 204.6 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 OAG37499.1 - 2.6e-13 49.4 0.1 8.7e-13 47.7 0.1 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DUF5624 PF18538.1 OAG37499.1 - 0.011 15.8 0.3 0.031 14.4 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5624) Nitrate_red_gam PF02665.14 OAG37499.1 - 0.018 14.6 0.0 0.025 14.1 0.0 1.1 1 0 0 1 1 1 0 Nitrate reductase gamma subunit Methyltransf_11 PF08241.12 OAG37500.1 - 1.6e-06 28.7 0.0 6.7e-06 26.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG37500.1 - 0.023 15.4 0.0 0.088 13.5 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain TcdB_toxin_midN PF12256.8 OAG37500.1 - 0.13 11.7 0.7 4 6.8 0.6 2.3 2 0 0 2 2 2 0 Insecticide toxin TcdB middle/N-terminal region Isochorismatase PF00857.20 OAG37501.1 - 1.4e-19 70.9 0.0 5.4e-19 69.0 0.0 1.8 1 1 0 1 1 1 1 Isochorismatase family EF-hand_6 PF13405.6 OAG37502.1 - 0.00039 20.1 0.0 0.0014 18.4 0.0 1.9 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 OAG37502.1 - 0.0014 19.0 0.0 0.02 15.3 0.1 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 OAG37502.1 - 0.0042 16.5 0.0 0.015 14.8 0.0 2.0 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 OAG37502.1 - 0.023 14.5 0.0 0.1 12.5 0.0 1.9 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_5 PF13202.6 OAG37502.1 - 0.034 13.6 0.0 0.083 12.4 0.0 1.6 1 0 0 1 1 1 0 EF hand Gasdermin_C PF17708.1 OAG37502.1 - 0.15 12.2 0.0 0.19 11.8 0.0 1.2 1 0 0 1 1 1 0 Gasdermin PUB domain Ribonuclease_3 PF00636.26 OAG37503.1 - 9.6e-32 109.7 0.0 2.7e-17 63.3 0.0 3.0 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 OAG37503.1 - 1.3e-22 80.3 1.1 1.3e-10 41.5 0.0 4.8 5 0 0 5 5 5 2 Ribonuclease-III-like Dicer_dimer PF03368.14 OAG37503.1 - 5e-19 68.3 0.2 2.6e-18 65.9 0.0 2.3 2 0 0 2 2 2 1 Dicer dimerisation domain Helicase_C PF00271.31 OAG37503.1 - 1.1e-11 45.1 0.0 3.7e-11 43.4 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 OAG37503.1 - 6.4e-09 35.8 0.0 1.5e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase dsrm PF00035.26 OAG37503.1 - 0.0032 18.1 0.3 0.047 14.4 0.1 2.6 2 0 0 2 2 2 1 Double-stranded RNA binding motif AAA_22 PF13401.6 OAG37503.1 - 0.0078 16.5 0.0 0.023 14.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 OAG37503.1 - 0.0079 16.2 0.0 0.018 15.0 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DNA_pol3_delta2 PF13177.6 OAG37504.1 - 3e-10 40.1 0.0 5.5e-10 39.3 0.0 1.4 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 OAG37504.1 - 5.4e-06 26.9 0.1 1.5e-05 25.5 0.1 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 OAG37504.1 - 0.00079 19.8 0.0 0.002 18.5 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA_22 PF13401.6 OAG37504.1 - 0.001 19.4 0.3 0.0059 16.9 0.2 2.3 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 OAG37504.1 - 0.0085 15.8 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OAG37504.1 - 0.029 14.7 0.7 0.23 11.8 0.2 2.5 2 1 0 2 2 2 0 AAA ATPase domain AAA_24 PF13479.6 OAG37504.1 - 0.086 12.6 0.1 0.22 11.3 0.1 1.6 1 1 0 1 1 1 0 AAA domain RuvB_N PF05496.12 OAG37504.1 - 0.11 12.2 0.0 1.8 8.3 0.0 2.3 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_29 PF13555.6 OAG37504.1 - 0.14 11.9 0.1 1.7 8.4 0.0 2.5 2 1 1 3 3 3 0 P-loop containing region of AAA domain DNA_pol3_delta PF06144.13 OAG37504.1 - 0.16 11.7 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase III, delta subunit Rad17 PF03215.15 OAG37504.1 - 0.17 11.8 0.0 0.26 11.2 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain Resolvase PF00239.21 OAG37504.1 - 0.31 11.2 2.6 0.82 9.8 0.4 2.6 3 1 1 4 4 4 0 Resolvase, N terminal domain RINGv PF12906.7 OAG37506.1 - 5.7e-06 26.4 3.8 8.1e-06 25.9 1.7 2.1 2 0 0 2 2 2 1 RING-variant domain UPF0547 PF10571.9 OAG37506.1 - 5.7 7.1 5.7 1.2 9.2 1.3 2.0 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 p450 PF00067.22 OAG37507.1 - 3.9e-53 180.8 0.0 9.3e-53 179.6 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 AAA_11 PF13086.6 OAG37509.1 - 3e-59 200.9 1.4 3.2e-59 200.8 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_12 PF13087.6 OAG37509.1 - 6.6e-58 195.6 0.0 8.4e-57 192.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 OAG37509.1 - 4.1e-12 46.2 0.0 1e-10 41.7 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OAG37509.1 - 1.2e-10 41.9 0.0 7.2e-10 39.4 0.0 2.3 2 1 0 2 2 2 1 AAA domain DUF2075 PF09848.9 OAG37509.1 - 5.9e-10 38.9 0.2 4e-09 36.2 0.2 2.0 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 OAG37509.1 - 2e-06 27.9 0.0 6.2e-06 26.3 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 OAG37509.1 - 2.5e-06 27.2 0.0 7e-06 25.8 0.0 1.6 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.18 OAG37509.1 - 1.3e-05 25.0 0.0 0.25 11.0 0.0 3.3 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.14 OAG37509.1 - 4.9e-05 23.3 0.0 0.031 14.1 0.0 3.2 2 1 0 2 2 2 1 Helicase AAA_22 PF13401.6 OAG37509.1 - 6e-05 23.3 0.4 0.0034 17.6 0.1 3.0 2 1 0 2 2 1 1 AAA domain PIF1 PF05970.14 OAG37509.1 - 0.00038 19.8 0.0 0.52 9.4 0.0 2.2 2 0 0 2 2 2 2 PIF1-like helicase AAA_5 PF07728.14 OAG37509.1 - 0.0011 19.0 0.0 0.03 14.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OAG37509.1 - 0.0017 18.8 0.0 0.0051 17.2 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain PhoH PF02562.16 OAG37509.1 - 0.0018 17.8 0.0 0.035 13.6 0.0 2.6 3 0 0 3 3 3 1 PhoH-like protein 4HB_MCP_1 PF12729.7 OAG37509.1 - 0.0086 15.6 0.9 0.096 12.2 0.0 2.2 2 0 0 2 2 2 1 Four helix bundle sensory module for signal transduction DEAD PF00270.29 OAG37509.1 - 0.011 15.6 0.1 0.33 10.7 0.1 2.5 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA_10 PF12846.7 OAG37509.1 - 0.014 14.4 0.0 0.024 13.6 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA PF00004.29 OAG37509.1 - 0.016 15.6 0.0 0.064 13.7 0.0 2.0 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) UvrD_C PF13361.6 OAG37509.1 - 0.017 14.5 1.0 2.1 7.6 0.0 2.7 2 2 1 3 3 3 0 UvrD-like helicase C-terminal domain AAA_25 PF13481.6 OAG37509.1 - 0.019 14.6 0.0 0.25 10.9 0.0 2.6 2 1 0 3 3 3 0 AAA domain NTPase_1 PF03266.15 OAG37509.1 - 0.02 14.8 0.3 1.5 8.7 0.0 2.5 2 0 0 2 2 2 0 NTPase AAA_24 PF13479.6 OAG37509.1 - 0.02 14.6 0.0 0.16 11.7 0.0 2.3 1 1 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.9 OAG37509.1 - 0.024 13.6 0.0 0.044 12.7 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain T2SSE PF00437.20 OAG37509.1 - 0.061 12.4 0.0 0.13 11.3 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein Zot PF05707.12 OAG37509.1 - 0.077 12.6 0.0 0.36 10.5 0.0 2.0 1 1 1 2 2 2 0 Zonular occludens toxin (Zot) TK PF00265.18 OAG37509.1 - 0.13 12.2 0.0 4.8 7.0 0.0 2.4 2 0 0 2 2 2 0 Thymidine kinase ABC_tran PF00005.27 OAG37509.1 - 0.14 12.7 0.0 0.61 10.6 0.0 2.2 2 0 0 2 2 1 0 ABC transporter Flavi_DEAD PF07652.14 OAG37509.1 - 0.15 12.0 0.1 0.75 9.8 0.0 2.2 3 0 0 3 3 2 0 Flavivirus DEAD domain CLZ PF16526.5 OAG37510.1 - 0.0024 18.2 0.8 0.19 12.1 0.5 2.4 2 0 0 2 2 2 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels EzrA PF06160.12 OAG37510.1 - 0.045 11.9 0.2 0.065 11.4 0.2 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA FliT PF05400.13 OAG37510.1 - 0.047 14.5 0.8 0.047 14.5 0.8 1.9 2 0 0 2 2 2 0 Flagellar protein FliT Tiam_CC_Ex PF18385.1 OAG37510.1 - 0.08 13.3 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 T-lymphoma invasion and metastasis CC-Ex domain XkdW PF09636.10 OAG37510.1 - 0.13 12.4 0.2 0.5 10.5 0.1 2.0 2 0 0 2 2 2 0 XkdW protein OmpH PF03938.14 OAG37510.1 - 0.16 12.3 1.3 0.29 11.4 1.3 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) PIG-F PF06699.11 OAG37511.1 - 1e-48 165.9 5.8 1.3e-48 165.5 5.8 1.1 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F Cyclin_N PF00134.23 OAG37512.1 - 1.8e-11 43.9 0.0 3.3e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 OAG37512.1 - 1.3e-07 32.1 0.0 3.1e-07 30.9 0.0 1.6 2 0 0 2 2 2 1 Cyclin DUF3149 PF11346.8 OAG37514.1 - 0.16 11.6 4.8 0.24 11.0 4.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) Hexapep PF00132.24 OAG37516.1 - 3e-11 42.6 4.9 1.5e-05 24.6 1.1 4.7 3 1 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 OAG37516.1 - 0.0033 17.1 0.6 0.025 14.3 0.3 2.6 4 0 0 4 4 4 1 Hexapeptide repeat of succinyl-transferase Protoglobin PF11563.8 OAG37517.1 - 3.6e-48 163.4 0.2 4.6e-48 163.1 0.2 1.1 1 0 0 1 1 1 1 Protoglobin Lactamase_B_2 PF12706.7 OAG37518.1 - 4.6e-23 81.8 0.0 1.4e-22 80.2 0.0 1.8 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 OAG37518.1 - 3.9e-06 26.8 0.0 1.4e-05 25.1 0.0 1.9 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 OAG37518.1 - 0.1 12.6 0.0 0.25 11.3 0.0 1.6 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily Herpes_DNAp_acc PF04929.12 OAG37519.1 - 7.5 5.4 7.7 11 4.9 7.7 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Amino_oxidase PF01593.24 OAG37520.1 - 3.2e-47 161.9 0.0 4.8e-47 161.3 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OAG37520.1 - 9.9e-16 57.7 0.1 2.6e-15 56.4 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAG37520.1 - 5.6e-07 29.1 0.8 1.2e-06 28.0 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAG37520.1 - 3.1e-06 27.0 3.6 1.7e-05 24.6 3.6 2.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 OAG37520.1 - 3.8e-06 27.4 0.4 1.8e-05 25.2 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAG37520.1 - 0.00013 20.8 0.2 0.00026 19.9 0.2 1.4 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 OAG37520.1 - 0.00023 20.4 0.5 0.00036 19.7 0.5 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 OAG37520.1 - 0.00032 20.2 0.1 0.00048 19.6 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 OAG37520.1 - 0.00054 19.3 0.7 0.00093 18.5 0.7 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 OAG37520.1 - 0.00062 19.1 0.2 0.0012 18.2 0.2 1.4 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 OAG37520.1 - 0.0011 18.2 0.3 0.0016 17.6 0.3 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 OAG37520.1 - 0.0032 16.8 0.0 0.0051 16.1 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 OAG37520.1 - 0.0036 17.2 0.1 0.0081 16.1 0.1 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 OAG37520.1 - 0.041 12.9 0.4 0.084 11.9 0.5 1.4 2 0 0 2 2 2 0 Lycopene cyclase protein Homeodomain PF00046.29 OAG37521.1 - 2.5e-14 52.9 1.3 4.5e-14 52.0 1.3 1.4 1 0 0 1 1 1 1 Homeodomain NAD_binding_10 PF13460.6 OAG37522.1 - 1e-10 41.8 0.0 7.3e-08 32.5 0.0 2.9 3 0 0 3 3 3 2 NAD(P)H-binding NmrA PF05368.13 OAG37522.1 - 1.1e-08 34.9 0.0 1.7e-07 31.0 0.0 2.1 1 1 0 1 1 1 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 OAG37522.1 - 0.0055 17.0 0.0 0.013 15.8 0.0 1.6 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 OAG37522.1 - 0.011 16.2 0.0 0.022 15.2 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 OAG37522.1 - 0.055 13.5 0.1 0.084 12.9 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ADH_zinc_N PF00107.26 OAG37523.1 - 8.3e-10 38.7 0.0 3.3e-09 36.8 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG37523.1 - 3.3e-05 23.7 0.2 0.00058 19.7 0.0 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 OAG37523.1 - 0.022 15.8 0.0 0.052 14.6 0.0 1.7 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Abhydrolase_1 PF00561.20 OAG37524.1 - 9.1e-23 81.2 0.2 4.5e-22 78.9 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG37524.1 - 1.3e-17 65.2 0.1 2.5e-15 57.7 0.1 2.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG37524.1 - 2.3e-17 63.1 0.0 8.4e-16 58.0 0.0 2.3 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Esterase PF00756.20 OAG37524.1 - 6.5e-07 29.3 0.0 1.9e-06 27.7 0.0 1.8 1 0 0 1 1 1 1 Putative esterase DUF915 PF06028.11 OAG37524.1 - 0.00012 21.6 0.0 0.00023 20.6 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) LIDHydrolase PF10230.9 OAG37524.1 - 0.0015 18.1 0.0 0.0032 17.1 0.0 1.5 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_2 PF02230.16 OAG37524.1 - 0.0033 17.2 0.0 1.5 8.5 0.0 3.0 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Chlorophyllase2 PF12740.7 OAG37524.1 - 0.0054 15.7 0.0 0.0092 14.9 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 OAG37524.1 - 0.046 12.7 0.0 0.076 12.0 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase BAAT_C PF08840.11 OAG37524.1 - 0.049 13.6 0.0 0.87 9.5 0.0 2.2 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal PGAP1 PF07819.13 OAG37524.1 - 0.066 12.9 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_3 PF07859.13 OAG37524.1 - 0.073 12.9 0.0 0.29 10.9 0.0 1.9 2 0 0 2 2 2 0 alpha/beta hydrolase fold Lipase_3 PF01764.25 OAG37524.1 - 0.14 12.0 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Peptidase_S9 PF00326.21 OAG37524.1 - 0.15 11.5 0.0 0.43 10.0 0.0 1.8 1 0 0 1 1 1 0 Prolyl oligopeptidase family Thioesterase PF00975.20 OAG37524.1 - 0.29 11.2 1.4 1.4 9.0 0.3 2.6 2 1 0 2 2 2 0 Thioesterase domain Spo7 PF03907.13 OAG37525.1 - 2.9e-83 278.7 0.3 2.9e-83 278.7 0.3 1.8 2 0 0 2 2 2 1 Spo7-like protein PAP2 PF01569.21 OAG37526.1 - 5.3e-23 81.3 2.2 5.3e-23 81.3 2.2 1.8 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 OAG37526.1 - 0.12 12.0 8.9 2.1 8.0 8.9 2.5 1 1 0 1 1 1 0 PAP2 superfamily SET PF00856.28 OAG37527.1 - 0.0011 19.4 0.0 0.0066 16.8 0.0 2.1 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.18 OAG37527.1 - 0.0038 17.3 4.8 0.0094 16.0 4.8 1.7 1 0 0 1 1 1 1 MYND finger FSIP1 PF15554.6 OAG37527.1 - 0.088 11.9 0.0 0.13 11.4 0.0 1.1 1 0 0 1 1 1 0 FSIP1 family zf-CRD PF17979.1 OAG37527.1 - 0.41 10.7 2.9 0.82 9.8 2.9 1.4 1 0 0 1 1 1 0 Cysteine rich domain with multizinc binding regions PS_Dcarbxylase PF02666.15 OAG37528.1 - 2.5e-54 183.9 0.0 3.3e-54 183.5 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Ank_2 PF12796.7 OAG37529.1 - 2.3e-15 57.0 4.1 3.6e-12 46.7 1.2 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAG37529.1 - 7.3e-15 55.1 4.1 5.6e-10 39.5 0.6 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG37529.1 - 3.9e-10 39.1 4.5 0.00023 21.4 0.1 4.2 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 OAG37529.1 - 6.2e-07 29.6 3.5 2.5e-05 24.4 0.2 3.4 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 OAG37529.1 - 4.2e-06 26.9 14.5 0.0012 19.2 1.1 3.8 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.7 OAG37530.1 - 1.2e-44 150.7 0.4 1.6e-11 44.6 0.0 5.1 2 1 4 6 6 6 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OAG37530.1 - 6.9e-35 115.1 1.6 9.2e-05 22.6 0.1 8.1 8 0 0 8 8 8 7 Ankyrin repeat Ank PF00023.30 OAG37530.1 - 6e-32 108.7 4.0 3e-08 33.8 0.1 7.9 8 0 0 8 8 8 5 Ankyrin repeat Ank_4 PF13637.6 OAG37530.1 - 1.9e-29 101.6 2.9 1.3e-07 32.0 0.0 6.5 3 1 5 8 8 8 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 OAG37530.1 - 1.1e-26 92.5 1.3 2.8e-07 30.7 0.0 6.0 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Pkinase PF00069.25 OAG37531.1 - 0.00074 19.0 0.0 0.001 18.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Beta-lactamase PF00144.24 OAG37532.1 - 9.4e-36 123.7 0.2 1.2e-35 123.3 0.2 1.1 1 0 0 1 1 1 1 Beta-lactamase WD40 PF00400.32 OAG37533.1 - 3.4e-19 68.8 19.3 5.6e-07 30.2 0.5 6.6 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG37533.1 - 0.0045 17.3 0.1 0.053 13.8 0.0 2.6 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain APG6_N PF17675.1 OAG37534.1 - 0.0024 18.4 26.1 0.032 14.8 7.3 3.3 1 1 3 4 4 4 3 Apg6 coiled-coil region Leu_zip PF15294.6 OAG37534.1 - 0.0048 16.5 10.6 0.15 11.5 1.6 2.4 1 1 1 2 2 2 2 Leucine zipper Tropomyosin_1 PF12718.7 OAG37534.1 - 0.0074 16.5 20.7 0.011 15.9 12.8 2.7 1 1 1 2 2 2 1 Tropomyosin like Mei5 PF10376.9 OAG37534.1 - 0.018 14.9 8.4 0.013 15.4 7.0 1.6 1 1 0 1 1 1 0 Double-strand recombination repair protein Prefoldin PF02996.17 OAG37534.1 - 0.053 13.4 12.6 5.7 6.9 0.1 4.2 3 1 1 4 4 4 0 Prefoldin subunit PI3K_P85_iSH2 PF16454.5 OAG37534.1 - 0.055 13.1 15.8 0.18 11.4 7.0 3.4 2 1 1 3 3 3 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain HMMR_N PF15905.5 OAG37534.1 - 0.077 12.5 15.1 0.21 11.0 15.1 1.7 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal ATG16 PF08614.11 OAG37534.1 - 0.091 13.0 27.0 1.2 9.3 1.9 3.3 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) DUF3450 PF11932.8 OAG37534.1 - 0.43 9.8 19.9 3.1 7.0 10.7 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) DUF724 PF05266.14 OAG37534.1 - 0.52 10.1 14.7 0.025 14.4 3.2 2.7 2 1 0 3 3 3 0 Protein of unknown function (DUF724) JIP_LZII PF16471.5 OAG37534.1 - 0.68 10.2 16.5 0.57 10.4 1.5 4.3 3 2 2 5 5 5 0 JNK-interacting protein leucine zipper II KASH_CCD PF14662.6 OAG37534.1 - 0.7 9.7 19.2 0.2 11.5 5.8 3.6 3 1 1 4 4 4 0 Coiled-coil region of CCDC155 or KASH Fez1 PF06818.15 OAG37534.1 - 0.71 10.3 19.2 21 5.5 19.2 2.1 1 1 0 1 1 1 0 Fez1 GAS PF13851.6 OAG37534.1 - 0.78 9.0 21.9 0.23 10.8 8.7 3.0 2 1 0 3 3 3 0 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.9 OAG37534.1 - 0.91 9.5 23.6 2 8.4 9.3 3.4 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MbeD_MobD PF04899.12 OAG37534.1 - 1.9 8.7 12.1 2.6 8.2 5.4 3.2 3 0 0 3 3 3 0 MbeD/MobD like Pox_A_type_inc PF04508.12 OAG37534.1 - 2.9 7.9 9.1 15 5.6 0.3 3.1 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat DUF5082 PF16888.5 OAG37534.1 - 3 8.2 19.5 3.1 8.1 1.9 4.2 2 1 1 4 4 4 0 Domain of unknown function (DUF5082) UPF0242 PF06785.11 OAG37534.1 - 3.5 7.7 15.8 29 4.7 0.2 2.6 1 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF4164 PF13747.6 OAG37534.1 - 5 7.5 20.0 0.41 10.9 4.9 3.7 3 1 1 4 4 4 0 Domain of unknown function (DUF4164) DivIC PF04977.15 OAG37534.1 - 5 7.0 21.1 1.1 9.1 3.3 4.2 4 0 0 4 4 4 0 Septum formation initiator Prefoldin_2 PF01920.20 OAG37534.1 - 6.2 6.8 19.8 4.2 7.4 1.4 4.1 3 1 1 4 4 4 0 Prefoldin subunit HetR_C PF18460.1 OAG37534.1 - 6.3 6.8 5.8 6.6 6.7 0.3 2.9 3 0 0 3 3 3 0 Heterocyst differentiation regulator C-terminal Hood domain DUF4472 PF14739.6 OAG37534.1 - 6.4 7.6 21.4 0.84 10.4 1.1 3.9 2 1 1 4 4 4 0 Domain of unknown function (DUF4472) DASH_Dam1 PF08653.10 OAG37534.1 - 6.9 6.6 6.5 22 5.0 0.0 3.6 4 0 0 4 4 4 0 DASH complex subunit Dam1 TSC22 PF01166.18 OAG37534.1 - 7.7 6.9 9.3 5.9 7.3 0.3 3.7 4 0 0 4 4 4 0 TSC-22/dip/bun family Jnk-SapK_ap_N PF09744.9 OAG37534.1 - 9.1 6.5 24.8 6.8 6.9 7.3 3.3 2 1 1 3 3 3 0 JNK_SAPK-associated protein-1 CsoS2_M PF12288.8 OAG37535.1 - 0.011 15.2 3.5 0.011 15.2 3.5 1.9 1 1 1 2 2 2 0 Carboxysome shell peptide mid-region Methyltransf_25 PF13649.6 OAG37536.1 - 1.2e-12 48.4 0.0 3e-12 47.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG37536.1 - 1.5e-11 44.8 0.0 3.7e-11 43.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAG37536.1 - 3.4e-10 39.7 0.0 8.6e-10 38.3 0.0 1.6 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 OAG37536.1 - 6.9e-08 32.5 0.0 2.2e-07 30.9 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG37536.1 - 3.8e-06 26.8 0.0 6.1e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG37536.1 - 0.0001 23.0 0.0 0.0002 22.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OAG37536.1 - 0.0021 17.7 0.0 0.0057 16.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase small domain RrnaAD PF00398.20 OAG37536.1 - 0.095 11.8 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase COPIIcoated_ERV PF07970.12 OAG37538.1 - 1.2e-35 123.4 0.0 2.4e-35 122.4 0.0 1.4 1 1 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 OAG37538.1 - 2.9e-24 85.2 0.0 4.5e-24 84.6 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) RabGAP-TBC PF00566.18 OAG37539.1 - 4.9e-32 111.3 0.0 1.2e-31 110.1 0.0 1.6 1 1 0 1 1 1 1 Rab-GTPase-TBC domain MatE PF01554.18 OAG37540.1 - 3.4e-50 169.8 22.4 5e-31 107.5 4.4 2.2 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 OAG37540.1 - 2.3e-05 24.5 8.2 2.3e-05 24.5 8.2 4.0 2 2 1 4 4 4 2 Polysaccharide biosynthesis C-terminal domain TPP_enzyme_N PF02776.18 OAG37541.1 - 5.1e-31 107.6 0.2 1.4e-30 106.2 0.2 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 OAG37541.1 - 1.2e-17 63.9 0.0 2.1e-17 63.1 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 OAG37541.1 - 3.3e-14 52.9 0.0 7.1e-14 51.9 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain SRP68 PF16969.5 OAG37542.1 - 2e-176 588.3 3.2 2.2e-176 588.2 3.2 1.0 1 0 0 1 1 1 1 RNA-binding signal recognition particle 68 TPR_2 PF07719.17 OAG37542.1 - 0.041 14.0 2.9 6.5 7.1 0.5 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat T3SSipB PF16535.5 OAG37542.1 - 6.7 7.2 10.3 0.61 10.5 0.4 3.0 3 0 0 3 3 3 0 Type III cell invasion protein SipB PPR_2 PF13041.6 OAG37543.1 - 1.4e-22 79.6 2.4 1.5e-07 31.5 0.0 8.1 7 1 3 10 10 10 4 PPR repeat family PPR PF01535.20 OAG37543.1 - 6.4e-18 63.7 0.0 0.00056 20.0 0.0 9.9 11 0 0 11 11 11 3 PPR repeat PPR_3 PF13812.6 OAG37543.1 - 1.9e-17 63.1 0.0 5.6e-07 29.5 0.0 6.6 5 1 3 8 8 8 6 Pentatricopeptide repeat domain PPR_long PF17177.4 OAG37543.1 - 9.5e-13 48.0 0.2 9.3e-08 31.7 0.0 4.9 2 2 5 7 7 7 4 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 OAG37543.1 - 7.4e-10 38.4 0.0 0.0075 16.0 0.0 5.8 7 0 0 7 7 7 2 PPR repeat HTH_43 PF09904.9 OAG37544.1 - 0.081 12.9 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn helix PPDK_N PF01326.19 OAG37544.1 - 0.17 11.1 0.0 0.31 10.3 0.0 1.4 1 0 0 1 1 1 0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain Choline_transpo PF04515.12 OAG37545.1 - 9e-81 271.6 24.4 9e-81 271.6 24.4 2.1 2 0 0 2 2 2 2 Plasma-membrane choline transporter Pex14_N PF04695.13 OAG37545.1 - 0.02 15.6 7.1 0.044 14.4 7.1 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region zf-C2H2 PF00096.26 OAG37546.1 - 4e-05 23.8 13.8 0.17 12.4 0.6 5.0 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-C2H2_aberr PF17017.5 OAG37546.1 - 0.00089 19.4 1.6 0.00095 19.4 0.1 1.7 2 0 0 2 2 2 1 Aberrant zinc-finger DUF1644 PF07800.12 OAG37546.1 - 0.026 14.6 1.2 0.026 14.6 1.2 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1644) zf-C2H2_4 PF13894.6 OAG37546.1 - 0.35 11.8 13.2 11 7.1 0.1 4.4 4 1 0 4 4 4 0 C2H2-type zinc finger DUF3425 PF11905.8 OAG37547.1 - 3.1e-09 36.8 0.2 6.6e-09 35.8 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Zn_clus PF00172.18 OAG37547.1 - 5.8e-09 35.9 4.2 9.9e-09 35.2 4.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain F-box-like PF12937.7 OAG37548.1 - 0.0018 18.1 0.3 0.016 15.1 0.3 2.5 1 1 0 1 1 1 1 F-box-like Meth_synt_2 PF01717.18 OAG37549.1 - 4.1e-11 42.7 0.0 6.5e-07 28.9 0.0 2.4 2 1 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 OAG37549.1 - 0.1 12.1 0.0 0.34 10.4 0.0 1.8 2 0 0 2 2 2 0 Cobalamin-independent synthase, N-terminal domain Gly-zipper_Omp PF13488.6 OAG37551.1 - 0.0016 18.4 4.2 0.0028 17.6 4.2 1.3 1 0 0 1 1 1 1 Glycine zipper Bacteriocin_IIc PF10439.9 OAG37551.1 - 0.14 12.3 7.9 0.2 11.8 7.9 1.2 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Rick_17kDa_Anti PF05433.15 OAG37551.1 - 0.23 11.3 11.9 0.37 10.7 11.9 1.4 1 0 0 1 1 1 0 Glycine zipper 2TM domain Gly-zipper_YMGG PF13441.6 OAG37551.1 - 0.24 11.2 7.6 0.42 10.4 7.6 1.4 1 0 0 1 1 1 0 YMGG-like Gly-zipper Ribonucleas_3_3 PF14622.6 OAG37552.1 - 2.4e-07 31.0 0.2 0.0018 18.4 0.1 2.6 2 1 0 2 2 2 2 Ribonuclease-III-like dsrm PF00035.26 OAG37552.1 - 5.8e-07 30.1 0.1 1.5e-06 28.8 0.0 1.7 2 0 0 2 2 2 1 Double-stranded RNA binding motif Ribonuclease_3 PF00636.26 OAG37552.1 - 0.014 16.1 0.0 0.19 12.4 0.0 2.4 1 1 0 1 1 1 0 Ribonuclease III domain Fungal_trans PF04082.18 OAG37554.1 - 5.5e-13 48.6 0.9 1.3e-12 47.3 0.1 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain ADH_zinc_N PF00107.26 OAG37555.1 - 3.1e-10 40.1 0.2 5.3e-10 39.4 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG37555.1 - 2.9e-09 36.8 0.0 5.6e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PfkB PF00294.24 OAG37556.1 - 1.8e-08 34.0 0.0 3e-08 33.3 0.0 1.6 1 1 0 1 1 1 1 pfkB family carbohydrate kinase PALP PF00291.25 OAG37557.1 - 2.8e-61 207.5 0.0 3.1e-61 207.3 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PTH2 PF01981.16 OAG37558.1 - 4.3e-41 139.9 0.2 5.8e-41 139.5 0.2 1.2 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 GCIP PF13324.6 OAG37558.1 - 0.013 15.2 1.3 0.016 14.8 1.3 1.1 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting VEFS-Box PF09733.9 OAG37558.1 - 0.036 13.9 1.0 0.052 13.4 1.0 1.2 1 0 0 1 1 1 0 VEFS-Box of polycomb protein DUF688 PF05097.12 OAG37558.1 - 1.4 8.0 4.4 1.9 7.5 4.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF688) DNA_pol_phi PF04931.13 OAG37558.1 - 2.9 5.9 7.8 3.5 5.6 7.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 OAG37558.1 - 3.3 7.0 10.0 5.2 6.3 10.0 1.3 1 0 0 1 1 1 0 NOA36 protein Cupin_2 PF07883.11 OAG37559.1 - 2.1e-11 43.4 0.4 3.2e-11 42.8 0.4 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 OAG37559.1 - 0.00043 19.9 0.0 0.00059 19.5 0.0 1.2 1 0 0 1 1 1 1 Cupin MannoseP_isomer PF01050.18 OAG37559.1 - 0.0044 16.9 0.0 0.0056 16.6 0.0 1.1 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase MBOAT PF03062.19 OAG37561.1 - 7.3e-49 167.0 14.8 1.2e-48 166.3 14.8 1.3 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family DUF3951 PF13131.6 OAG37561.1 - 0.011 15.9 0.3 0.011 15.9 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3951) T4SS_CagC PF16943.5 OAG37561.1 - 0.052 13.7 0.3 0.11 12.7 0.3 1.5 1 0 0 1 1 1 0 Cag pathogenicity island, type IV secretory system GST_N_2 PF13409.6 OAG37562.1 - 3.2e-23 81.8 0.1 7.3e-23 80.7 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAG37562.1 - 1.1e-09 38.1 0.0 2.3e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 OAG37562.1 - 1.5e-05 25.3 0.2 0.00078 19.8 0.2 2.6 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OAG37562.1 - 0.0041 17.3 0.0 0.009 16.2 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OAG37562.1 - 0.08 13.1 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 OAG37562.1 - 0.14 12.7 0.0 0.26 11.9 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain adh_short PF00106.25 OAG37563.1 - 7.3e-20 71.3 0.0 4.9e-16 58.8 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAG37563.1 - 2.5e-10 40.3 0.0 8.3e-08 32.1 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG37563.1 - 9.1e-07 29.0 0.0 1.6e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OAG37563.1 - 0.0042 16.3 0.0 0.006 15.7 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 OAG37563.1 - 0.02 15.1 0.0 0.041 14.1 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 OAG37563.1 - 0.027 14.5 0.0 0.046 13.8 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.6 OAG37563.1 - 0.043 13.7 0.0 0.071 13.0 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding Aldedh PF00171.22 OAG37564.1 - 1.2e-143 479.0 0.0 1.4e-143 478.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Peptidase_M20 PF01546.28 OAG37565.1 - 5.7e-08 32.7 0.1 1e-07 31.9 0.1 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 OAG37565.1 - 0.0043 16.9 0.0 0.031 14.2 0.0 2.2 2 0 0 2 2 2 1 Peptidase dimerisation domain Zn_clus PF00172.18 OAG37566.1 - 3.3e-07 30.3 11.4 5e-07 29.7 11.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 OAG37567.1 - 5.9e-31 107.7 33.7 4.8e-30 104.7 33.8 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 OAG37567.1 - 1.1e-05 25.0 18.1 3.7e-05 23.2 3.8 2.3 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB DUF2417 PF10329.9 OAG37567.1 - 0.97 8.8 3.8 1.7 8.0 3.2 1.7 2 0 0 2 2 2 0 Region of unknown function (DUF2417) Hexapep PF00132.24 OAG37568.1 - 3.4e-13 48.8 7.1 1e-05 25.0 3.0 4.8 4 1 1 5 5 5 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 OAG37568.1 - 0.0026 17.5 2.3 3.4 7.5 0.2 4.3 3 2 1 4 4 4 2 Hexapeptide repeat of succinyl-transferase WLM PF08325.10 OAG37569.1 - 6.4e-28 98.1 0.5 2.1e-27 96.5 0.5 1.9 1 1 0 1 1 1 1 WLM domain DUF45 PF01863.17 OAG37569.1 - 2.2e-07 31.1 0.4 5.3e-07 29.9 0.4 1.6 1 0 0 1 1 1 1 Protein of unknown function DUF45 Zn_ribbon_17 PF17120.5 OAG37569.1 - 0.32 10.7 6.1 0.04 13.6 2.0 1.7 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RanBP PF00641.18 OAG37569.1 - 4.7 6.6 10.8 0.39 10.1 3.5 2.6 3 0 0 3 3 3 0 Zn-finger in Ran binding protein and others CAP59_mtransfer PF11735.8 OAG37570.1 - 4e-68 229.7 0.0 5.2e-68 229.3 0.0 1.2 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Acyl-CoA_dh_1 PF00441.24 OAG37571.1 - 8.9e-14 52.0 1.0 2.5e-08 34.3 0.0 2.4 2 0 0 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 OAG37571.1 - 4.3e-11 42.9 0.0 1.7e-10 40.9 0.0 2.0 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain AidB_N PF18158.1 OAG37571.1 - 1e-09 38.5 0.0 4.7e-09 36.3 0.0 2.1 2 0 0 2 2 2 1 Adaptive response protein AidB N-terminal domain GTP_EFTU PF00009.27 OAG37572.1 - 5.3e-06 26.1 0.0 6.6e-05 22.5 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OAG37572.1 - 0.0071 16.3 0.0 2.1 8.2 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OAG37572.1 - 0.048 13.7 0.0 0.17 12.0 0.0 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.6 OAG37572.1 - 0.052 13.9 1.9 0.087 13.2 0.6 2.1 2 1 0 2 2 2 0 AAA ATPase domain Pkr1 PF08636.10 OAG37573.1 - 2.3e-31 107.8 4.5 3e-31 107.4 4.5 1.1 1 0 0 1 1 1 1 ER protein Pkr1 MSA-2c PF12238.8 OAG37573.1 - 0.03 14.4 2.4 0.039 14.0 2.4 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c FHIPEP PF00771.20 OAG37573.1 - 0.1 11.0 0.0 0.12 10.8 0.0 1.1 1 0 0 1 1 1 0 FHIPEP family OAD_gamma PF04277.13 OAG37573.1 - 0.37 11.4 3.4 1.3 9.7 3.4 2.1 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain F-box-like PF12937.7 OAG37575.1 - 0.00036 20.4 0.2 0.0011 18.8 0.2 1.9 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 OAG37576.1 - 2.9e-05 23.9 0.1 8.5e-05 22.4 0.0 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 OAG37576.1 - 0.004 17.0 0.4 0.019 14.8 0.1 2.3 3 0 0 3 3 3 1 F-box domain F-box_4 PF15966.5 OAG37576.1 - 0.0067 16.3 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 F-box HemY_N PF07219.13 OAG37576.1 - 0.17 12.1 0.0 0.33 11.2 0.0 1.3 1 0 0 1 1 1 0 HemY protein N-terminus Complex1_LYR_2 PF13233.6 OAG37577.1 - 2.8e-18 66.4 0.2 4.6e-18 65.7 0.2 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 OAG37577.1 - 1.8e-09 37.5 0.1 3.4e-09 36.6 0.1 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) TauD PF02668.16 OAG37578.1 - 3.6e-26 92.5 0.0 5e-26 92.1 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Fungal_trans_2 PF11951.8 OAG37579.1 - 1.1e-10 40.9 0.0 2.1e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cullin PF00888.22 OAG37580.1 - 4e-21 75.3 0.0 6.6e-21 74.6 0.0 1.2 1 0 0 1 1 1 1 Cullin family ANAPC2 PF08672.11 OAG37580.1 - 3.3e-20 72.4 0.0 7.3e-20 71.2 0.0 1.7 1 0 0 1 1 1 1 Anaphase promoting complex (APC) subunit 2 PIR PF00399.19 OAG37582.1 - 4.6e-76 249.0 156.5 3.5e-07 29.6 3.7 14.4 10 4 4 14 14 14 14 Yeast PIR protein repeat HA2 PF04408.23 OAG37583.1 - 4.5e-24 84.8 0.1 1.2e-23 83.4 0.1 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 OAG37583.1 - 2e-13 50.5 0.0 4.7e-13 49.3 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 OAG37583.1 - 2.2e-12 47.3 0.0 4.8e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 OAG37583.1 - 1.1e-05 25.7 0.0 3.4e-05 24.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 OAG37583.1 - 0.00011 22.0 0.0 0.00024 20.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_29 PF13555.6 OAG37583.1 - 0.0088 15.8 0.1 0.029 14.1 0.0 1.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain T2SSE PF00437.20 OAG37583.1 - 0.021 13.9 0.0 0.042 12.9 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_19 PF13245.6 OAG37583.1 - 0.047 14.0 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 OAG37583.1 - 0.058 12.8 0.0 0.19 11.1 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein ABC_tran PF00005.27 OAG37583.1 - 0.063 13.8 0.0 0.22 12.0 0.0 2.0 1 0 0 1 1 1 0 ABC transporter DEAD PF00270.29 OAG37584.1 - 3.5e-30 105.1 0.0 7.1e-30 104.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAG37584.1 - 5.1e-16 59.0 0.2 2.9e-15 56.6 0.1 2.3 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG37584.1 - 3.7e-06 27.1 0.1 2.8e-05 24.2 0.0 2.5 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Nefa_Nip30_N PF10187.9 OAG37584.1 - 0.44 10.9 6.0 0.2 12.0 0.7 2.4 2 0 0 2 2 2 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 PH PF00169.29 OAG37585.1 - 4e-09 36.9 0.0 9.9e-09 35.7 0.0 1.7 1 0 0 1 1 1 1 PH domain Anillin PF08174.11 OAG37585.1 - 0.00011 22.6 0.1 0.0003 21.2 0.0 1.9 2 0 0 2 2 2 1 Cell division protein anillin Orthopox_F8 PF05886.11 OAG37585.1 - 0.063 13.4 0.1 0.31 11.2 0.1 2.2 1 0 0 1 1 1 0 Orthopoxvirus F8 protein Aldolase_II PF00596.21 OAG37586.1 - 2.9e-46 157.8 0.2 3.6e-46 157.4 0.2 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain AOX PF01786.17 OAG37588.1 - 3.9e-95 317.5 0.2 4.7e-95 317.2 0.2 1.1 1 0 0 1 1 1 1 Alternative oxidase KAR9 PF08580.10 OAG37589.1 - 3.6e-159 531.5 30.5 4.3e-159 531.2 28.2 2.1 1 1 0 1 1 1 1 Yeast cortical protein KAR9 PLU-1 PF08429.11 OAG37589.1 - 0.00018 20.8 2.4 0.15 11.2 0.1 3.2 2 1 1 3 3 3 2 PLU-1-like protein Helo_like_N PF17111.5 OAG37589.1 - 0.069 12.5 2.3 1.8 7.9 0.1 2.6 2 0 0 2 2 2 0 Fungal N-terminal domain of STAND proteins RuvA_C PF07499.13 OAG37589.1 - 0.21 12.1 0.7 0.58 10.7 0.7 1.8 1 0 0 1 1 1 0 RuvA, C-terminal domain DUF4332 PF14229.6 OAG37589.1 - 0.3 11.3 4.4 0.36 11.1 0.6 2.8 4 0 0 4 4 4 0 Domain of unknown function (DUF4332) DNA_repr_REX1B PF14966.6 OAG37589.1 - 0.48 11.1 1.8 31 5.3 0.2 2.9 2 0 0 2 2 2 0 DNA repair REX1-B DUF4611 PF15387.6 OAG37589.1 - 2.1 8.6 6.7 30 4.9 3.6 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) DUF2353 PF09789.9 OAG37589.1 - 6 6.1 7.4 1.1 8.6 2.2 2.0 2 0 0 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) F-box-like PF12937.7 OAG37590.1 - 6.4e-06 26.0 0.3 1.3e-05 24.9 0.3 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAG37590.1 - 0.0004 20.2 0.2 0.00086 19.1 0.2 1.5 1 0 0 1 1 1 1 F-box domain BRO1 PF03097.18 OAG37590.1 - 0.018 13.9 0.4 0.033 13.0 0.4 1.3 1 0 0 1 1 1 0 BRO1-like domain TPR_2 PF07719.17 OAG37590.1 - 0.035 14.2 0.1 0.3 11.3 0.2 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat MIT PF04212.18 OAG37590.1 - 0.062 13.4 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain Mito_carr PF00153.27 OAG37591.1 - 2.3e-60 200.5 2.0 6.1e-21 74.1 0.0 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 OAG37591.1 - 0.015 14.5 1.9 0.18 10.9 0.1 2.5 3 0 0 3 3 3 0 Gammaproteobacterial serine protease DUF295 PF03478.18 OAG37591.1 - 0.082 12.5 0.6 14 5.4 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF295) VWA PF00092.28 OAG37592.1 - 5.5e-12 46.3 0.4 1.4e-11 45.0 0.2 1.7 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_2 PF13519.6 OAG37592.1 - 2.1e-11 44.4 0.0 6.3e-11 42.9 0.0 1.9 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 OAG37592.1 - 0.0033 16.8 0.5 1.1 8.6 0.1 2.3 2 0 0 2 2 2 2 VWA domain containing CoxE-like protein MARVEL PF01284.23 OAG37593.1 - 1.5e-09 38.1 11.1 8.8e-08 32.3 7.6 2.1 2 0 0 2 2 2 2 Membrane-associating domain DUF4328 PF14219.6 OAG37593.1 - 0.5 9.9 0.0 0.5 9.9 0.0 3.3 3 1 1 4 4 4 0 Domain of unknown function (DUF4328) DHHC PF01529.20 OAG37594.1 - 7.1e-31 107.1 6.3 7.1e-31 107.1 6.3 2.0 3 0 0 3 3 3 1 DHHC palmitoyltransferase zf-UBR PF02207.20 OAG37594.1 - 0.18 12.0 6.4 0.29 11.3 6.4 1.2 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) Rad17 PF03215.15 OAG37595.1 - 2.1e-23 83.2 0.0 4.1e-23 82.3 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain Peptidase_M16 PF00675.20 OAG37595.1 - 0.00087 19.3 0.0 0.0022 18.0 0.0 1.7 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) AAA_16 PF13191.6 OAG37595.1 - 0.001 19.5 0.1 0.0025 18.2 0.1 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 OAG37595.1 - 0.0022 17.8 0.2 0.0089 15.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 OAG37595.1 - 0.0032 17.9 0.0 0.0088 16.5 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OAG37595.1 - 0.0037 17.5 0.0 0.013 15.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 OAG37595.1 - 0.009 15.1 0.0 0.016 14.3 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein RuvB_N PF05496.12 OAG37595.1 - 0.023 14.4 0.0 0.042 13.6 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 OAG37595.1 - 0.076 13.0 0.1 0.15 12.0 0.1 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 OAG37595.1 - 0.11 13.0 0.2 0.44 11.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 OAG37595.1 - 0.22 11.1 0.3 0.37 10.4 0.3 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Nbs1_C PF08599.10 OAG37595.1 - 0.93 9.7 4.4 2.3 8.4 0.8 2.6 2 0 0 2 2 2 0 DNA damage repair protein Nbs1 VTC PF09359.10 OAG37596.1 - 3.7e-100 334.9 0.1 3.7e-100 334.9 0.1 1.5 2 0 0 2 2 2 1 VTC domain DUF202 PF02656.15 OAG37596.1 - 8.4e-12 45.4 3.7 8.4e-12 45.4 3.7 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF202) SPX PF03105.19 OAG37596.1 - 1.8e-11 44.6 24.1 3.3e-06 27.3 0.1 4.2 3 1 1 4 4 4 3 SPX domain DUF2294 PF10057.9 OAG37596.1 - 0.027 14.6 0.5 1.7 8.8 0.1 2.8 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2294) LXG PF04740.12 OAG37596.1 - 0.79 9.4 7.5 0.11 12.2 2.7 2.0 2 1 0 2 2 2 0 LXG domain of WXG superfamily F-box-like PF12937.7 OAG37597.1 - 6.3e-07 29.2 0.5 1.4e-06 28.1 0.5 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAG37597.1 - 0.00014 21.7 0.1 0.0004 20.2 0.1 1.8 1 0 0 1 1 1 1 F-box domain F-box-like_2 PF13013.6 OAG37597.1 - 0.067 13.2 0.0 0.22 11.5 0.0 1.9 1 0 0 1 1 1 0 F-box-like domain 2Fe-2S_thioredx PF01257.19 OAG37598.1 - 4.7e-59 198.4 0.3 5.8e-59 198.1 0.3 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin Ribophorin_I PF04597.14 OAG37599.1 - 8.4e-150 499.8 0.2 9.6e-150 499.6 0.2 1.0 1 0 0 1 1 1 1 Ribophorin I DNA_pol_B_thumb PF14791.6 OAG37600.1 - 2.3e-21 75.7 0.6 1.6e-20 73.0 0.2 2.5 3 0 0 3 3 3 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.9 OAG37600.1 - 3.7e-20 71.5 0.4 8.6e-20 70.3 0.4 1.7 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda DNA_pol_B_palm PF14792.6 OAG37600.1 - 5.3e-16 58.9 0.1 1.4e-15 57.4 0.1 1.8 1 1 0 1 1 1 1 DNA polymerase beta palm HHH_8 PF14716.6 OAG37600.1 - 2.2e-08 34.3 0.0 1.1e-07 32.1 0.0 2.2 3 0 0 3 3 3 1 Helix-hairpin-helix domain BRCT_2 PF16589.5 OAG37600.1 - 0.0014 19.0 0.0 0.043 14.2 0.0 2.3 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain HHH_5 PF14520.6 OAG37600.1 - 0.0092 16.6 0.0 0.16 12.6 0.0 2.4 2 0 0 2 2 2 1 Helix-hairpin-helix domain CRISPR_assoc PF08798.11 OAG37600.1 - 0.086 12.9 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 CRISPR associated protein NTP_transf_2 PF01909.23 OAG37600.1 - 0.13 12.6 0.1 0.33 11.3 0.1 1.7 1 0 0 1 1 1 0 Nucleotidyltransferase domain HEPN_RES_NTD1 PF18870.1 OAG37600.1 - 0.15 12.2 0.0 0.33 11.2 0.0 1.5 1 0 0 1 1 1 0 HEPN/RES N-terminal domain 1 PBP1_TM PF14812.6 OAG37600.1 - 0.29 11.5 4.4 3.1 8.2 0.4 2.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TPR_12 PF13424.6 OAG37601.1 - 0.18 12.1 4.5 7.4 6.9 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat HECT PF00632.25 OAG37604.1 - 2e-70 237.7 0.0 4.6e-70 236.5 0.0 1.6 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) AZUL PF16558.5 OAG37604.1 - 3.8e-17 62.3 2.1 8.8e-17 61.1 2.1 1.6 1 0 0 1 1 1 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A Tim17 PF02466.19 OAG37605.1 - 1.2e-31 109.3 7.7 1.8e-31 108.8 7.7 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family TraQ PF09679.10 OAG37606.1 - 0.0012 18.7 0.1 0.0039 17.1 0.1 1.8 1 0 0 1 1 1 1 Type-F conjugative transfer system pilin chaperone (TraQ) LMBR1 PF04791.16 OAG37606.1 - 1.1 8.1 2.6 2 7.3 2.6 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein Thiamine_BP PF01910.17 OAG37607.1 - 6.3e-32 109.4 0.1 7.5e-32 109.1 0.1 1.1 1 0 0 1 1 1 1 Thiamine-binding protein PspB PF06667.12 OAG37607.1 - 0.11 12.5 0.1 0.17 11.9 0.1 1.4 1 0 0 1 1 1 0 Phage shock protein B DUF1335 PF07056.11 OAG37607.1 - 0.17 12.0 0.0 0.6 10.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1335) DUF3425 PF11905.8 OAG37608.1 - 7.2e-12 45.4 0.0 2.2e-11 43.8 0.0 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) Fungal_trans PF04082.18 OAG37609.1 - 3.4e-12 46.0 0.4 6.7e-12 45.0 0.4 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG37609.1 - 5.6e-05 23.2 8.0 5.6e-05 23.2 8.0 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.26 OAG37609.1 - 0.00033 20.9 4.7 0.00033 20.9 4.7 3.1 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAG37609.1 - 0.018 15.8 4.0 0.018 15.8 4.0 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_6 PF13912.6 OAG37609.1 - 0.11 12.5 8.7 0.037 14.0 1.4 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger DUF2039 PF10217.9 OAG37609.1 - 0.41 11.0 5.6 0.99 9.8 5.6 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) zf-BED PF02892.15 OAG37609.1 - 2.1 8.4 8.0 0.22 11.6 1.3 2.8 3 0 0 3 3 3 0 BED zinc finger FMO-like PF00743.19 OAG37610.1 - 6.5e-13 47.9 0.8 9.1e-12 44.2 0.4 2.6 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 OAG37610.1 - 1.1e-10 41.3 0.5 3.3e-05 23.2 0.0 3.6 3 1 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 OAG37610.1 - 1.1e-07 32.0 0.0 2.8e-07 30.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAG37610.1 - 6e-07 29.0 0.0 0.00022 20.6 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG37610.1 - 6.2e-05 22.4 0.1 0.0018 17.6 0.1 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAG37610.1 - 0.19 11.7 2.6 0.22 11.5 0.0 2.4 4 0 0 4 4 4 0 FAD-NAD(P)-binding DAO PF01266.24 OAG37610.1 - 0.2 11.2 3.3 2.1 7.8 0.0 2.9 1 1 1 4 4 4 0 FAD dependent oxidoreductase GIDA PF01134.22 OAG37610.1 - 0.25 10.4 0.1 23 3.9 0.0 2.4 2 0 0 2 2 2 0 Glucose inhibited division protein A Fungal_trans PF04082.18 OAG37611.1 - 5.4e-17 61.7 0.2 1.1e-16 60.7 0.1 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain V-SNARE PF05008.15 OAG37612.1 - 3.3e-05 24.2 0.1 5.1e-05 23.6 0.1 1.3 1 0 0 1 1 1 1 Vesicle transport v-SNARE protein N-terminus ubiquitin PF00240.23 OAG37613.1 - 3.9e-14 52.1 0.1 5.4e-13 48.5 0.1 2.2 1 1 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 OAG37613.1 - 0.00015 21.5 0.0 0.00034 20.4 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 OAG37613.1 - 0.2 12.1 0.1 0.34 11.4 0.1 1.3 1 0 0 1 1 1 0 Ubiquitin-like domain Sugar_tr PF00083.24 OAG37614.1 - 2.5e-77 260.7 30.2 2.8e-77 260.5 30.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG37614.1 - 3.2e-29 102.0 29.0 3.2e-29 102.0 29.0 2.0 1 1 0 2 2 2 1 Major Facilitator Superfamily DUF3593 PF12159.8 OAG37614.1 - 0.38 10.8 5.5 0.2 11.7 0.4 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3593) TMEM215 PF15746.5 OAG37614.1 - 0.69 9.3 1.8 4.8 6.6 0.5 2.2 2 0 0 2 2 2 0 TMEM215 family FMO-like PF00743.19 OAG37615.1 - 1.2e-13 50.4 0.9 3.4e-12 45.6 0.2 2.6 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 OAG37615.1 - 8.1e-08 31.8 0.0 0.0062 15.7 0.0 4.1 4 1 0 4 4 4 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 OAG37615.1 - 2e-07 31.1 0.0 7e-07 29.4 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAG37615.1 - 0.00041 19.7 0.0 0.034 13.4 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAG37615.1 - 0.00072 19.6 0.0 0.25 11.3 0.0 3.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 OAG37615.1 - 0.011 15.0 0.2 0.49 9.6 0.0 3.1 2 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Malic_M PF03949.15 OAG37615.1 - 0.025 13.8 0.2 1.1 8.5 0.0 2.3 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain NAD_Gly3P_dh_N PF01210.23 OAG37615.1 - 0.044 13.8 0.1 2 8.4 0.0 2.3 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Mqo PF06039.15 OAG37615.1 - 0.047 12.2 0.0 0.57 8.7 0.0 2.0 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) Thi4 PF01946.17 OAG37615.1 - 0.13 11.5 0.1 1.2 8.3 0.0 2.2 2 0 0 2 2 2 0 Thi4 family p450 PF00067.22 OAG37616.1 - 2.9e-58 197.8 0.0 3.7e-58 197.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Cyclase PF04199.13 OAG37617.1 - 1.6e-15 57.6 0.0 3.8e-15 56.3 0.0 1.4 1 1 0 1 1 1 1 Putative cyclase adh_short_C2 PF13561.6 OAG37618.1 - 2.9e-54 184.1 0.0 3.5e-54 183.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG37618.1 - 1.4e-44 152.0 0.2 1.7e-44 151.6 0.2 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG37618.1 - 1.6e-07 31.5 0.6 7.9e-07 29.2 0.6 1.9 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 OAG37618.1 - 0.021 13.8 0.0 0.03 13.3 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 OAG37618.1 - 0.041 13.4 0.0 1.1 8.6 0.0 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 OAG37619.1 - 6e-53 179.6 0.0 8.9e-53 179.1 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 OAG37619.1 - 6.7e-50 169.9 0.0 9.7e-50 169.4 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 OAG37619.1 - 2.8e-11 43.3 0.0 5.3e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 OAG37619.1 - 1e-06 29.0 0.1 2.9e-06 27.5 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.19 OAG37619.1 - 1.7e-05 24.0 0.0 6.3e-05 22.1 0.0 2.0 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 OAG37619.1 - 0.0013 18.2 0.0 0.003 17.0 0.0 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 OAG37619.1 - 0.0072 15.5 0.0 0.013 14.7 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.25 OAG37620.1 - 7.7e-19 67.9 0.0 1.6e-15 57.1 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAG37620.1 - 1.1e-10 41.5 0.0 4.5e-07 29.7 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG37620.1 - 6.2e-06 26.2 0.0 1.2e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 KR domain MFS_1 PF07690.16 OAG37621.1 - 2.3e-32 112.3 23.6 2.3e-32 112.3 23.6 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily AMP-binding PF00501.28 OAG37622.1 - 5.6e-58 196.5 0.0 7.4e-58 196.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG37622.1 - 2.6e-13 50.7 0.0 5.5e-13 49.7 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF1774 PF08611.10 OAG37625.1 - 1.7e-35 121.2 1.9 5.4e-35 119.6 1.9 1.9 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1774) Peptidase_M28 PF04389.17 OAG37626.1 - 3.4e-30 105.2 0.1 9.1e-30 103.8 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M28 Peptidase_M20 PF01546.28 OAG37626.1 - 1.1e-06 28.6 0.1 1.9e-06 27.7 0.1 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 R3H-assoc PF13902.6 OAG37627.1 - 2e-21 76.8 4.8 1.3e-20 74.1 4.7 2.2 2 0 0 2 2 2 1 R3H-associated N-terminal domain DND1_DSRM PF14709.7 OAG37629.1 - 0.07 13.4 0.0 0.13 12.5 0.0 1.4 1 1 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 TGT PF01702.18 OAG37630.1 - 4.3e-146 486.6 0.0 5e-146 486.4 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase ApbA_C PF08546.11 OAG37631.1 - 9.7e-27 93.7 0.0 1.7e-26 92.8 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 OAG37631.1 - 1.9e-24 86.0 0.0 2.8e-24 85.5 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Hist_deacetyl PF00850.19 OAG37632.1 - 1.4e-47 162.7 0.2 2.2e-47 162.1 0.2 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Cyclase PF04199.13 OAG37633.1 - 5.5e-15 55.8 0.1 7.4e-15 55.4 0.1 1.2 1 0 0 1 1 1 1 Putative cyclase Sugar_tr PF00083.24 OAG37634.1 - 5.1e-68 230.0 17.2 5.7e-68 229.8 17.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG37634.1 - 3e-17 62.6 32.1 3.4e-09 36.1 15.7 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily Popeye PF04831.13 OAG37634.1 - 0.34 11.1 0.0 0.34 11.1 0.0 3.4 3 1 1 4 4 4 0 Popeye protein conserved region NmrA PF05368.13 OAG37635.1 - 5.7e-28 98.1 0.0 7.4e-28 97.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG37635.1 - 9.5e-14 51.7 0.0 4.2e-13 49.6 0.0 2.0 1 1 1 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 OAG37635.1 - 0.05 13.1 0.0 0.26 10.7 0.0 2.0 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 OAG37635.1 - 0.05 13.7 0.0 0.11 12.6 0.0 1.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Semialdhyde_dh PF01118.24 OAG37635.1 - 0.051 14.0 0.1 0.4 11.1 0.1 2.4 3 0 0 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 OAG37635.1 - 0.054 13.6 0.1 0.12 12.5 0.1 1.6 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Sugar_tr PF00083.24 OAG37636.1 - 8.4e-85 285.3 23.2 9.7e-85 285.1 23.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG37636.1 - 4e-31 108.2 39.9 2.9e-27 95.5 20.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_5 PF05631.14 OAG37636.1 - 0.00066 18.7 0.7 0.00066 18.7 0.7 2.2 2 0 0 2 2 2 1 Sugar-tranasporters, 12 TM Fungal_trans PF04082.18 OAG37637.1 - 8.1e-17 61.1 4.3 2e-16 59.8 4.3 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Abhydrolase_3 PF07859.13 OAG37638.1 - 5.2e-47 160.4 0.0 8e-47 159.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Epimerase PF01370.21 OAG37638.1 - 7.7e-06 25.5 0.0 1e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family COesterase PF00135.28 OAG37638.1 - 0.0011 17.9 0.2 0.0036 16.2 0.0 1.7 2 0 0 2 2 2 1 Carboxylesterase family GDP_Man_Dehyd PF16363.5 OAG37638.1 - 0.016 14.6 0.0 0.071 12.5 0.0 1.8 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Say1_Mug180 PF10340.9 OAG37638.1 - 0.022 13.6 0.0 0.23 10.3 0.0 2.0 2 0 0 2 2 2 0 Steryl acetyl hydrolase NAD_binding_10 PF13460.6 OAG37638.1 - 0.027 14.3 0.0 0.045 13.6 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding Hydrolase_4 PF12146.8 OAG37638.1 - 0.032 13.5 0.0 6.5 6.0 0.0 2.4 1 1 0 2 2 2 0 Serine aminopeptidase, S33 Acyl-CoA_dh_M PF02770.19 OAG37638.1 - 0.11 12.7 0.0 0.29 11.4 0.0 1.7 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, middle domain FMO-like PF00743.19 OAG37639.1 - 5.4e-20 71.3 1.2 4.1e-17 61.8 0.6 2.6 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OAG37639.1 - 2.4e-09 37.3 0.0 1.1e-08 35.1 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 OAG37639.1 - 2.3e-06 27.0 0.1 8e-05 21.9 0.1 2.3 1 1 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 OAG37639.1 - 0.00068 19.0 0.1 0.0026 17.1 0.0 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAG37639.1 - 0.00099 18.4 0.0 0.019 14.2 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAG37639.1 - 0.013 15.4 0.3 1.2 9.1 0.0 2.7 3 0 0 3 3 3 0 FAD-NAD(P)-binding Thi4 PF01946.17 OAG37639.1 - 0.095 11.9 0.0 10 5.3 0.0 2.2 2 0 0 2 2 2 0 Thi4 family ARL2_Bind_BART PF11527.8 OAG37639.1 - 0.23 11.6 1.1 0.41 10.8 0.2 1.8 2 0 0 2 2 2 0 The ARF-like 2 binding protein BART APH PF01636.23 OAG37640.1 - 3.3e-05 23.9 0.0 6.5e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family APH PF01636.23 OAG37641.1 - 2.3e-10 40.8 0.2 3.2e-09 37.1 0.0 2.6 2 1 0 2 2 2 1 Phosphotransferase enzyme family DUF1679 PF07914.11 OAG37641.1 - 1e-05 24.6 0.0 4.1e-05 22.6 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1679) Choline_kinase PF01633.20 OAG37641.1 - 0.019 14.5 0.1 0.16 11.6 0.0 2.0 2 0 0 2 2 2 0 Choline/ethanolamine kinase EcKinase PF02958.20 OAG37641.1 - 0.052 12.8 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 Ecdysteroid kinase Chitin_synth_1 PF01644.17 OAG37643.1 - 3.5e-78 261.2 0.2 5e-78 260.7 0.2 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 OAG37643.1 - 1e-27 95.9 0.2 2.4e-27 94.7 0.2 1.7 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 OAG37643.1 - 2.7e-21 75.8 0.5 2.5e-19 69.3 0.0 2.4 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 OAG37643.1 - 9.7e-07 28.9 0.2 9.7e-07 28.9 0.2 2.0 2 0 0 2 2 2 1 Glycosyl transferase family group 2 DUF4106 PF13388.6 OAG37644.1 - 0.24 10.6 5.5 0.53 9.5 5.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Fungal_trans PF04082.18 OAG37645.1 - 6e-12 45.2 0.7 1.4e-11 44.0 0.7 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain QCR10 PF09796.9 OAG37645.1 - 0.088 12.9 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Nuc_recep-AF1 PF11825.8 OAG37645.1 - 0.089 12.8 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Nuclear/hormone receptor activator site AF-1 DNA_pol_B PF00136.21 OAG37648.1 - 1.5e-119 399.7 3.8 3.3e-118 395.3 2.0 2.2 2 0 0 2 2 2 2 DNA polymerase family B zf-DNA_Pol PF08996.10 OAG37648.1 - 1.2e-69 233.7 3.8 2.8e-69 232.6 3.8 1.7 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.19 OAG37648.1 - 4.8e-40 137.7 0.0 1.1e-39 136.5 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.8 OAG37648.1 - 6e-25 87.1 7.0 6e-25 87.1 7.0 3.2 4 0 0 4 4 4 1 DNA polymerase alpha subunit p180 N terminal DNA_pol_B_2 PF03175.13 OAG37648.1 - 0.00099 18.1 0.4 0.0023 16.9 0.0 1.7 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral Phos_pyr_kin PF08543.12 OAG37649.1 - 1.1e-79 267.3 1.0 1.5e-79 266.9 1.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.16 OAG37649.1 - 3.4e-43 147.9 1.3 1.5e-39 136.0 0.3 2.2 1 1 1 2 2 2 2 TENA/THI-4/PQQC family PfkB PF00294.24 OAG37649.1 - 0.00026 20.4 0.2 0.0034 16.7 0.1 2.3 2 1 0 2 2 2 1 pfkB family carbohydrate kinase HK PF02110.15 OAG37649.1 - 0.0011 18.4 0.8 0.005 16.3 0.1 2.0 2 0 0 2 2 2 1 Hydroxyethylthiazole kinase family Methyltransf_28 PF02636.17 OAG37650.1 - 6.5e-74 248.9 0.0 1.8e-73 247.4 0.0 1.8 2 0 0 2 2 2 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PPR_2 PF13041.6 OAG37650.1 - 4.1e-24 84.5 0.0 8.5e-19 67.5 0.0 2.8 2 0 0 2 2 2 2 PPR repeat family PPR PF01535.20 OAG37650.1 - 2.6e-05 24.2 0.0 0.0062 16.7 0.0 4.1 3 0 0 3 3 3 1 PPR repeat PPR_3 PF13812.6 OAG37650.1 - 7e-05 22.8 0.0 0.032 14.3 0.0 3.3 3 1 1 4 4 4 1 Pentatricopeptide repeat domain PPR_1 PF12854.7 OAG37650.1 - 0.0001 21.9 0.0 0.57 9.9 0.0 4.0 3 1 0 3 3 3 2 PPR repeat PPR_long PF17177.4 OAG37650.1 - 0.014 14.8 0.0 0.032 13.6 0.0 1.5 1 0 0 1 1 1 0 Pentacotripeptide-repeat region of PRORP FOXP-CC PF16159.5 OAG37651.1 - 0.11 13.2 0.9 0.22 12.2 0.9 1.5 1 1 0 1 1 1 0 FOXP coiled-coil domain zf-C2H2 PF00096.26 OAG37651.1 - 0.16 12.5 0.2 0.29 11.7 0.2 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type DUF5075 PF16825.5 OAG37651.1 - 0.2 11.4 1.5 0.42 10.3 1.5 1.5 1 0 0 1 1 1 0 IGP family C-type lectin domain YabA PF06156.13 OAG37651.1 - 7.3 7.3 6.4 2.4 8.8 0.2 2.1 1 1 1 2 2 2 0 Initiation control protein YabA Peptidase_S8 PF00082.22 OAG37654.1 - 8.2e-14 51.6 0.0 1.7e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 Subtilase family TPR_10 PF13374.6 OAG37654.1 - 0.00065 19.5 0.3 0.61 10.0 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 OAG37654.1 - 0.0027 17.9 0.0 1.5 9.2 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat pP_pnuc_1 PF18165.1 OAG37654.1 - 0.055 13.4 2.0 0.17 11.8 0.1 2.5 3 1 0 3 3 3 0 Predicted pPIWI-associating nuclease YoeB_toxin PF06769.14 OAG37654.1 - 0.064 13.3 0.6 0.81 9.8 0.0 2.7 3 0 0 3 3 3 0 YoeB-like toxin of bacterial type II toxin-antitoxin system FliT PF05400.13 OAG37654.1 - 0.72 10.7 3.3 11 6.9 0.0 3.4 3 0 0 3 3 3 0 Flagellar protein FliT DEAD PF00270.29 OAG37655.1 - 6.5e-50 169.3 0.0 1.4e-48 165.0 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAG37655.1 - 5.9e-31 107.1 0.0 2e-30 105.4 0.0 1.9 2 1 1 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG37655.1 - 3.9e-05 23.7 0.0 0.00012 22.1 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 OAG37655.1 - 0.0024 18.2 0.0 0.97 9.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain Helicase_C_2 PF13307.6 OAG37655.1 - 0.0051 17.0 0.0 0.0091 16.2 0.0 1.4 1 0 0 1 1 1 1 Helicase C-terminal domain UTP25 PF06862.12 OAG37655.1 - 0.007 15.2 0.1 1.1 7.9 0.0 2.3 2 0 0 2 2 2 2 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 ERCC3_RAD25_C PF16203.5 OAG37655.1 - 0.012 14.8 0.1 0.018 14.3 0.1 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase DUF5335 PF17269.2 OAG37655.1 - 0.037 13.9 0.1 0.064 13.1 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5335) AAA_22 PF13401.6 OAG37655.1 - 0.25 11.6 0.5 34 4.7 0.0 3.2 4 0 0 4 4 4 0 AAA domain GFA PF04828.14 OAG37656.1 - 1.7e-05 25.0 0.2 1.7e-05 25.0 0.2 1.7 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Zn_ribbon_SprT PF17283.2 OAG37656.1 - 0.067 13.1 0.6 0.067 13.1 0.6 2.9 3 0 0 3 3 3 0 SprT-like zinc ribbon domain Tnp_zf-ribbon_2 PF13842.6 OAG37656.1 - 0.13 13.1 5.0 0.51 11.2 0.2 2.4 2 0 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon p450 PF00067.22 OAG37657.1 - 2.2e-49 168.5 0.0 4.6e-49 167.4 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 ScsC_N PF18312.1 OAG37657.1 - 0.011 15.5 0.3 0.011 15.5 0.3 2.2 3 0 0 3 3 3 0 Copper resistance protein ScsC N-terminal domain Ribosomal_L30_N PF08079.12 OAG37658.1 - 8.1e-26 90.1 14.2 1.7e-25 89.0 14.2 1.6 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 OAG37658.1 - 7.6e-18 64.1 3.0 2e-17 62.8 3.0 1.8 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e MPM1 PF17234.2 OAG37658.1 - 0.066 13.5 0.2 0.11 12.7 0.2 1.3 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 EAP30 PF04157.16 OAG37659.1 - 1.9e-68 230.3 0.1 2.1e-68 230.1 0.1 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family Chlorophyllase PF07224.11 OAG37659.1 - 0.13 11.2 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase SNF2_N PF00176.23 OAG37660.1 - 2.2e-64 217.4 0.0 4.4e-64 216.4 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OAG37660.1 - 7e-19 68.2 0.0 2.3e-18 66.5 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG37660.1 - 4e-05 23.7 0.0 0.00019 21.5 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit TFIIF_beta PF02270.15 OAG37660.1 - 0.011 15.9 0.0 0.026 14.6 0.0 1.6 1 0 0 1 1 1 0 TFIIF, beta subunit HTH domain FapA PF03961.13 OAG37660.1 - 0.14 10.7 4.2 0.24 10.0 4.2 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Pkinase PF00069.25 OAG37661.1 - 3.5e-50 170.8 0.1 1.6e-49 168.7 0.1 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG37661.1 - 2.2e-23 82.8 0.1 6.5e-23 81.3 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 OAG37661.1 - 0.00044 20.2 0.1 0.00044 20.2 0.1 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 OAG37661.1 - 0.0028 17.3 0.1 0.011 15.4 0.1 1.9 1 1 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 OAG37661.1 - 0.69 9.5 2.7 0.33 10.5 0.2 1.7 2 0 0 2 2 2 0 Choline/ethanolamine kinase eIF-3c_N PF05470.12 OAG37662.1 - 6.7e-171 569.6 48.1 3.5e-134 448.3 3.8 3.3 1 1 2 3 3 3 2 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 OAG37662.1 - 1.5e-14 54.4 0.6 2.2e-12 47.4 0.0 3.3 2 0 0 2 2 2 1 PCI domain DUF1385 PF07136.11 OAG37662.1 - 0.024 13.9 0.0 0.085 12.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1385) SDA1 PF05285.12 OAG37662.1 - 5.9 6.2 33.5 12 5.3 33.5 1.4 1 0 0 1 1 1 0 SDA1 SLAC1 PF03595.17 OAG37663.1 - 1.9e-59 201.5 56.2 2.2e-59 201.3 56.2 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Gemini_mov PF01708.16 OAG37664.1 - 0.13 12.0 1.0 0.3 10.9 0.0 2.1 2 0 0 2 2 2 0 Geminivirus putative movement protein Pkinase PF00069.25 OAG37665.1 - 1.8e-40 139.0 0.0 2.2e-22 79.7 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAG37665.1 - 1.6e-13 50.6 0.1 5.3e-09 35.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAG37665.1 - 0.053 12.3 0.1 0.078 11.7 0.1 1.4 1 1 0 1 1 1 0 Fungal protein kinase Metallophos PF00149.28 OAG37666.1 - 1.8e-11 44.9 1.2 2.9e-11 44.3 1.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OAG37666.1 - 6e-06 26.6 0.0 3.9e-05 23.9 0.0 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DAGK_cat PF00781.24 OAG37668.1 - 2.7e-10 39.9 0.0 4.4e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain HET PF06985.11 OAG37669.1 - 1.3e-27 96.9 0.1 5.3e-26 91.7 0.0 2.5 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Nop14 PF04147.12 OAG37669.1 - 0.046 11.9 22.3 0.069 11.4 22.3 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 OAG37669.1 - 0.065 11.5 16.0 0.095 11.0 16.0 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4746 PF15928.5 OAG37669.1 - 0.065 12.6 8.4 0.11 12.0 8.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) RNA_pol_Rpc4 PF05132.14 OAG37669.1 - 0.087 13.3 0.6 0.15 12.5 0.6 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 Pinin_SDK_memA PF04696.13 OAG37669.1 - 0.093 12.8 11.2 0.19 11.8 11.2 1.4 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region THOC2_N PF16134.5 OAG37669.1 - 0.13 10.8 4.6 0.19 10.3 4.6 1.1 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus BUD22 PF09073.10 OAG37669.1 - 0.43 9.9 17.2 0.7 9.2 17.2 1.2 1 0 0 1 1 1 0 BUD22 Mpp10 PF04006.12 OAG37669.1 - 0.75 8.2 23.7 1.2 7.6 23.7 1.1 1 0 0 1 1 1 0 Mpp10 protein SDA1 PF05285.12 OAG37669.1 - 0.97 8.8 24.7 1.7 8.0 24.7 1.3 1 0 0 1 1 1 0 SDA1 NOA36 PF06524.12 OAG37669.1 - 1 8.6 19.9 2.1 7.6 19.9 1.5 1 0 0 1 1 1 0 NOA36 protein CDC27 PF09507.10 OAG37669.1 - 1.1 8.6 14.7 1.7 8.0 14.7 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 EIIBC-GUT_N PF03612.14 OAG37669.1 - 1.3 8.8 3.7 7.1 6.3 4.0 1.9 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus DUF2722 PF10846.8 OAG37669.1 - 2.5 6.9 9.7 4.6 6.1 9.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) CPSF100_C PF13299.6 OAG37669.1 - 2.7 8.1 8.0 6.7 6.9 8.0 1.6 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal RR_TM4-6 PF06459.12 OAG37669.1 - 4.5 7.0 13.7 8.8 6.1 13.7 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RPA43_OB PF17875.1 OAG37669.1 - 5 7.8 10.1 10 6.7 9.3 1.9 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I TFB6 PF17110.5 OAG37669.1 - 9 6.0 11.3 70 3.1 12.3 2.0 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH Paf1 PF03985.13 OAG37669.1 - 9.2 5.1 24.9 14 4.6 24.9 1.2 1 0 0 1 1 1 0 Paf1 GMC_oxred_N PF00732.19 OAG37670.1 - 4.2e-66 223.3 0.0 1.7e-65 221.4 0.0 1.8 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAG37670.1 - 1.9e-34 119.3 0.0 4.5e-34 118.1 0.0 1.7 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 OAG37670.1 - 1.8e-06 27.3 1.1 0.025 13.7 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 OAG37670.1 - 0.00053 19.1 0.9 0.0017 17.5 0.2 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 OAG37670.1 - 0.0064 16.7 0.0 0.017 15.3 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 OAG37670.1 - 0.0073 15.6 0.4 0.017 14.4 0.1 1.7 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 OAG37670.1 - 0.078 12.5 3.2 0.28 10.7 0.9 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase DUF5586 PF17824.1 OAG37671.1 - 3.7 6.5 9.3 9.8 5.2 3.2 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5586) FAM104 PF15434.6 OAG37671.1 - 4.3 7.9 6.8 4.1 8.0 2.5 2.3 2 0 0 2 2 2 0 Family 104 PGI PF00342.19 OAG37672.1 - 1.9e-235 782.0 1.4 2.2e-235 781.8 1.4 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase Arc_PepC PF06819.11 OAG37672.1 - 0.062 13.4 1.5 0.33 11.1 0.6 2.3 2 0 0 2 2 2 0 Archaeal Peptidase A24 C-terminal Domain RNase_T PF00929.24 OAG37673.1 - 0.014 16.0 0.0 0.19 12.3 0.0 2.4 2 0 0 2 2 2 0 Exonuclease BTK PF00779.19 OAG37673.1 - 0.052 13.4 0.8 0.12 12.2 0.8 1.6 1 0 0 1 1 1 0 BTK motif His_Phos_2 PF00328.22 OAG37674.1 - 4.2e-109 365.4 0.0 8e-109 364.5 0.0 1.5 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 OAG37674.1 - 5.2e-20 71.4 0.0 2.4e-17 62.9 0.0 2.6 1 1 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 OAG37674.1 - 4.2e-08 33.0 0.0 1e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Utp21 PF04192.12 OAG37675.1 - 4.3e-66 222.7 0.8 6.5e-66 222.2 0.8 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain ANAPC4_WD40 PF12894.7 OAG37675.1 - 1.4e-13 50.9 0.0 0.00021 21.5 0.0 6.0 2 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OAG37675.1 - 6.9e-11 42.5 21.9 0.0012 19.6 0.5 9.2 10 0 0 10 10 10 2 WD domain, G-beta repeat Utp12 PF04003.12 OAG37675.1 - 5.4e-05 23.5 0.0 0.00016 21.9 0.0 1.9 1 0 0 1 1 1 1 Dip2/Utp12 Family PQQ PF01011.21 OAG37675.1 - 0.046 13.7 0.0 14 5.8 0.0 3.0 2 0 0 2 2 2 0 PQQ enzyme repeat Coatomer_WDAD PF04053.14 OAG37675.1 - 0.2 10.6 0.0 0.79 8.7 0.0 1.8 2 0 0 2 2 2 0 Coatomer WD associated region Med13_C PF06333.12 OAG37675.1 - 5.9 6.0 8.1 0.17 11.1 0.1 2.3 2 1 0 2 2 2 0 Mediator complex subunit 13 C-terminal domain Fungal_trans_2 PF11951.8 OAG37678.1 - 0.027 13.3 0.4 0.041 12.7 0.4 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain adh_short_C2 PF13561.6 OAG37679.1 - 2.1e-52 178.0 3.1 2.6e-52 177.7 3.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG37679.1 - 1.4e-48 164.9 4.6 1.8e-48 164.6 4.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG37679.1 - 1.1e-08 35.2 0.6 1.8e-08 34.5 0.6 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OAG37679.1 - 0.013 14.6 0.7 0.018 14.2 0.7 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Epimerase PF01370.21 OAG37679.1 - 0.029 13.8 0.4 0.065 12.7 0.1 1.7 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family NAD_binding_7 PF13241.6 OAG37679.1 - 0.067 13.6 0.3 0.12 12.8 0.3 1.6 1 1 0 1 1 1 0 Putative NAD(P)-binding Sugar_tr PF00083.24 OAG37680.1 - 1.9e-85 287.5 18.3 2.2e-85 287.3 18.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG37680.1 - 3.3e-34 118.4 54.3 1.4e-29 103.2 23.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Amastin PF07344.11 OAG37680.1 - 0.15 11.9 7.4 3.9 7.3 1.7 2.6 2 0 0 2 2 2 0 Amastin surface glycoprotein Ni_hydr_CYTB PF01292.20 OAG37680.1 - 0.6 9.7 5.5 0.18 11.4 0.6 2.6 2 1 1 3 3 3 0 Prokaryotic cytochrome b561 Profilin PF00235.19 OAG37681.1 - 5.9e-53 178.5 0.5 6.6e-53 178.3 0.5 1.0 1 0 0 1 1 1 1 Profilin Tox-ODYAM1 PF15642.6 OAG37681.1 - 0.081 11.9 0.1 0.088 11.8 0.1 1.1 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus Ras PF00071.22 OAG37682.1 - 1.2e-64 216.8 0.0 1.5e-64 216.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAG37682.1 - 1.2e-33 115.8 0.1 1.7e-33 115.4 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAG37682.1 - 5.1e-13 48.8 0.0 6.3e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OAG37682.1 - 5.2e-05 22.9 0.0 0.0001 21.9 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OAG37682.1 - 0.00024 20.5 0.0 0.00031 20.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 OAG37682.1 - 0.0018 18.2 0.0 1.7 8.5 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OAG37682.1 - 0.0035 17.4 0.0 0.0076 16.3 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 OAG37682.1 - 0.023 14.1 0.0 0.027 13.9 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 OAG37682.1 - 0.049 13.2 0.0 0.21 11.1 0.0 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_22 PF13401.6 OAG37682.1 - 0.12 12.7 0.1 0.53 10.6 0.1 2.0 1 1 0 1 1 1 0 AAA domain NCA2 PF08637.10 OAG37683.1 - 1.6e-108 362.3 0.3 3.1e-108 361.3 0.3 1.5 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 Rox3 PF08633.10 OAG37683.1 - 0.12 12.7 0.0 0.22 11.8 0.0 1.3 1 0 0 1 1 1 0 Rox3 mediator complex subunit MIF4G_like PF09088.11 OAG37684.1 - 3.9e-90 300.7 0.2 5.7e-90 300.2 0.2 1.2 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.11 OAG37684.1 - 3.4e-71 239.9 0.1 4.7e-71 239.4 0.1 1.2 1 0 0 1 1 1 1 MIF4G like MIF4G PF02854.19 OAG37684.1 - 0.0014 18.3 0.0 0.0027 17.4 0.0 1.4 1 0 0 1 1 1 1 MIF4G domain HhH-GPD PF00730.25 OAG37685.1 - 0.00019 21.8 0.0 0.00024 21.5 0.0 1.2 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Sugar_tr PF00083.24 OAG37686.1 - 1.2e-89 301.3 24.3 1.4e-89 301.1 24.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG37686.1 - 1.9e-22 79.7 43.6 2.4e-15 56.3 16.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Lactamase_B PF00753.27 OAG37687.1 - 3.2e-07 30.6 0.1 6e-07 29.7 0.1 1.7 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OAG37687.1 - 0.00065 19.3 0.0 0.0016 18.0 0.0 1.7 2 0 0 2 2 2 1 Beta-lactamase superfamily domain FAD_binding_3 PF01494.19 OAG37688.1 - 7.3e-19 68.2 0.0 2e-10 40.5 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Amino_oxidase PF01593.24 OAG37688.1 - 0.00083 18.8 0.0 0.0037 16.6 0.0 1.9 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 OAG37688.1 - 0.073 13.6 0.7 18 6.0 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAG37688.1 - 0.087 12.0 0.1 6.3 5.9 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG37688.1 - 0.19 10.9 0.2 15 4.7 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Abhydrolase_6 PF12697.7 OAG37689.1 - 4e-19 70.1 0.2 8.8e-19 69.0 0.2 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAG37689.1 - 1.2e-17 64.5 0.0 8.4e-17 61.7 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAG37689.1 - 5.4e-11 42.2 0.0 1.1e-09 37.9 0.0 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 OAG37689.1 - 0.00087 19.2 0.0 0.31 10.8 0.0 2.6 2 1 1 3 3 3 2 Phospholipase/Carboxylesterase DsbC PF11412.8 OAG37689.1 - 0.035 14.2 0.1 0.56 10.3 0.0 2.5 2 1 1 3 3 3 0 Disulphide bond corrector protein DsbC ADH_N PF08240.12 OAG37690.1 - 5.4e-29 100.3 0.2 1.1e-28 99.3 0.1 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG37690.1 - 1.3e-16 60.7 1.5 2.6e-16 59.8 1.5 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAG37690.1 - 7.2e-10 40.0 0.1 1.2e-09 39.3 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Sacchrp_dh_NADP PF03435.18 OAG37690.1 - 0.002 18.4 0.8 0.0032 17.7 0.8 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Methyltransf_25 PF13649.6 OAG37690.1 - 0.051 14.3 0.1 0.095 13.4 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain Sugar_tr PF00083.24 OAG37691.1 - 7.5e-68 229.4 16.5 8.6e-68 229.2 16.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG37691.1 - 8e-28 97.4 43.9 4e-24 85.2 26.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily FMO-like PF00743.19 OAG37692.1 - 3.1e-14 52.3 0.0 1.1e-13 50.5 0.0 1.9 3 0 0 3 3 3 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 OAG37692.1 - 6.5e-13 48.6 0.0 5.6e-11 42.2 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG37692.1 - 3.2e-09 36.5 0.0 1.1e-08 34.8 0.0 1.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG37692.1 - 5.7e-08 32.9 0.0 5.6e-06 26.5 0.0 3.2 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 OAG37692.1 - 0.00073 19.6 0.1 0.11 12.5 0.1 3.4 3 1 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 OAG37692.1 - 0.0019 18.7 0.2 1.8 9.1 0.3 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAG37692.1 - 0.002 17.7 2.4 0.016 14.8 0.1 2.9 2 1 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 OAG37692.1 - 0.0064 15.6 0.0 0.69 8.9 0.0 2.3 2 0 0 2 2 2 1 Lycopene cyclase protein K_oxygenase PF13434.6 OAG37692.1 - 0.057 12.6 0.2 0.13 11.4 0.0 1.6 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Shikimate_DH PF01488.20 OAG37692.1 - 0.063 13.3 0.0 0.35 10.9 0.0 2.1 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 OAG37692.1 - 0.095 13.1 0.0 0.51 10.8 0.0 2.2 2 0 0 2 2 2 0 Putative NAD(P)-binding rve_3 PF13683.6 OAG37692.1 - 0.14 11.9 0.2 0.33 10.8 0.2 1.6 1 0 0 1 1 1 0 Integrase core domain GIDA PF01134.22 OAG37692.1 - 0.18 10.8 0.0 5.1 6.1 0.1 2.6 3 0 0 3 3 3 0 Glucose inhibited division protein A 2-Hacid_dh_C PF02826.19 OAG37692.1 - 0.2 11.0 0.0 0.36 10.2 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HI0933_like PF03486.14 OAG37692.1 - 0.25 10.0 0.2 20 3.7 0.1 2.8 3 0 0 3 3 3 0 HI0933-like protein adh_short PF00106.25 OAG37693.1 - 5.9e-46 156.4 2.2 7.2e-46 156.1 2.2 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG37693.1 - 6.7e-44 150.2 2.4 8.2e-44 149.9 2.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG37693.1 - 1.1e-13 51.5 0.5 1.5e-13 51.0 0.5 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 OAG37693.1 - 0.011 15.6 2.3 0.018 14.9 2.3 1.4 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltrans_RNA PF04452.14 OAG37693.1 - 0.016 14.6 0.1 0.022 14.1 0.1 1.2 1 0 0 1 1 1 0 RNA methyltransferase 2-Hacid_dh_C PF02826.19 OAG37693.1 - 0.037 13.4 0.3 0.059 12.7 0.3 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 OAG37693.1 - 0.066 12.8 0.4 0.1 12.2 0.4 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AdoHcyase_NAD PF00670.21 OAG37693.1 - 0.1 12.7 4.2 0.16 12.0 4.2 1.4 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Fungal_trans PF04082.18 OAG37694.1 - 4e-07 29.3 0.0 7e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain SPX PF03105.19 OAG37694.1 - 0.054 13.4 0.2 0.066 13.1 0.2 1.3 1 0 0 1 1 1 0 SPX domain Pkinase PF00069.25 OAG37695.1 - 1.3e-65 221.4 0.0 1.5e-65 221.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG37695.1 - 3e-25 89.0 0.0 3.9e-25 88.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAG37695.1 - 1.7e-06 27.6 0.0 1.2e-05 24.8 0.0 2.0 1 1 1 2 2 2 1 Kinase-like APH PF01636.23 OAG37695.1 - 0.00054 19.9 0.2 0.0068 16.4 0.0 2.4 2 1 1 3 3 3 1 Phosphotransferase enzyme family DUF1229 PF06797.11 OAG37695.1 - 0.0058 16.9 0.2 0.009 16.2 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1229) Kdo PF06293.14 OAG37695.1 - 0.12 11.8 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 OAG37695.1 - 0.13 11.8 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Porin_3 PF01459.22 OAG37696.1 - 1.6e-75 254.1 0.0 2e-75 253.8 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic porin Zds_C PF08632.10 OAG37696.1 - 0.0038 16.9 0.0 0.0086 15.8 0.0 1.5 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term 6PF2K PF01591.18 OAG37697.1 - 3.5e-62 209.6 0.0 5.8e-62 208.9 0.0 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 OAG37697.1 - 1.2e-19 70.7 0.1 5e-19 68.7 0.1 1.9 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) GSDH PF07995.11 OAG37697.1 - 0.07 12.4 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 Glucose / Sorbosone dehydrogenase Urm1 PF09138.11 OAG37698.1 - 7.1e-35 119.3 0.0 8e-35 119.1 0.0 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.20 OAG37698.1 - 0.014 16.0 0.0 0.018 15.7 0.0 1.2 1 0 0 1 1 1 0 ThiS family DUF2614 PF11023.8 OAG37699.1 - 0.28 11.3 2.6 0.28 11.3 0.6 1.9 2 0 0 2 2 2 0 Zinc-ribbon containing domain RTA1 PF04479.13 OAG37700.1 - 1.3e-36 126.2 7.1 1.5e-35 122.7 7.1 2.1 1 1 0 1 1 1 1 RTA1 like protein DUF2878 PF11086.8 OAG37700.1 - 0.11 12.7 4.6 0.065 13.4 1.7 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2878) WD40 PF00400.32 OAG37701.1 - 3e-32 110.1 36.8 3.1e-05 24.7 0.4 13.2 14 0 0 14 14 14 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG37701.1 - 1.9e-11 44.1 2.7 0.42 11.0 0.1 7.4 6 1 0 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OAG37701.1 - 3.7e-06 26.1 0.2 1.1 8.2 0.0 5.7 7 0 0 7 7 7 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 OAG37701.1 - 0.011 14.5 0.0 0.021 13.6 0.0 1.4 1 0 0 1 1 1 0 Nup133 N terminal like SGL PF08450.12 OAG37701.1 - 0.073 12.6 0.0 0.18 11.3 0.0 1.7 1 0 0 1 1 1 0 SMP-30/Gluconolactonase/LRE-like region ABC_tran PF00005.27 OAG37702.1 - 5.3e-15 56.1 0.3 1.3e-08 35.4 0.1 2.2 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 OAG37702.1 - 1.3e-10 41.6 0.8 0.00015 21.7 0.2 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 OAG37702.1 - 0.002 17.8 0.3 0.0046 16.7 0.3 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF3584 PF12128.8 OAG37702.1 - 0.0039 14.8 0.4 0.0052 14.4 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) AAA_25 PF13481.6 OAG37702.1 - 0.0079 15.8 0.1 0.017 14.7 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 OAG37702.1 - 0.0085 16.6 0.3 0.013 16.0 0.3 1.2 1 0 0 1 1 1 1 AAA domain PduV-EutP PF10662.9 OAG37702.1 - 0.013 15.2 0.0 0.02 14.7 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_15 PF13175.6 OAG37702.1 - 0.02 14.6 0.2 0.03 14.0 0.2 1.1 1 0 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 OAG37702.1 - 0.038 13.9 0.1 0.06 13.3 0.1 1.2 1 0 0 1 1 1 0 RsgA GTPase AAA_28 PF13521.6 OAG37702.1 - 0.043 14.1 0.2 0.073 13.3 0.2 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 OAG37702.1 - 0.053 13.9 0.1 0.092 13.1 0.1 1.4 1 0 0 1 1 1 0 AAA ATPase domain SMC_N PF02463.19 OAG37702.1 - 0.054 12.9 0.0 5.2 6.4 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain SRP54 PF00448.22 OAG37702.1 - 0.085 12.5 0.1 0.14 11.8 0.1 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_22 PF13401.6 OAG37702.1 - 0.11 12.8 0.1 0.18 12.1 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_13 PF13166.6 OAG37702.1 - 0.14 10.7 0.1 0.19 10.3 0.1 1.1 1 0 0 1 1 1 0 AAA domain DLIC PF05783.11 OAG37702.1 - 0.2 10.4 0.1 0.34 9.7 0.1 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) SH3_9 PF14604.6 OAG37703.1 - 1.2e-14 53.9 0.1 2.6e-14 52.8 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 OAG37703.1 - 7.8e-14 51.0 0.1 1.5e-13 50.1 0.1 1.5 1 0 0 1 1 1 1 SH3 domain BAR PF03114.18 OAG37703.1 - 1.3e-12 47.9 4.3 2.1e-12 47.2 4.3 1.3 1 1 0 1 1 1 1 BAR domain SH3_2 PF07653.17 OAG37703.1 - 1.4e-09 37.4 0.0 2.6e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain PIN_8 PF18476.1 OAG37703.1 - 0.0072 16.2 0.7 0.018 14.9 0.7 1.6 1 0 0 1 1 1 1 PIN like domain Fib_alpha PF08702.10 OAG37703.1 - 0.042 14.0 3.8 0.092 12.9 3.8 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family GAS PF13851.6 OAG37703.1 - 0.053 12.9 11.2 0.18 11.2 8.1 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Tnp_22_trimer PF17489.2 OAG37703.1 - 0.09 12.8 0.3 0.2 11.7 0.3 1.5 1 0 0 1 1 1 0 L1 transposable element trimerization domain CCDC-167 PF15188.6 OAG37703.1 - 7.1 7.0 7.4 3.8 7.9 3.3 2.2 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 DUF2439 PF10382.9 OAG37704.1 - 1.5e-26 92.5 0.2 2.5e-26 91.8 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) DIOX_N PF14226.6 OAG37705.1 - 4e-23 82.4 0.8 1.6e-22 80.5 0.8 1.9 1 1 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OAG37705.1 - 2e-19 69.9 0.1 1.2e-18 67.4 0.0 2.3 2 1 1 3 3 3 1 2OG-Fe(II) oxygenase superfamily SE PF08491.10 OAG37706.1 - 1.3e-105 352.4 0.0 1.8e-105 352.0 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.19 OAG37706.1 - 8.4e-13 48.3 0.0 1.8e-10 40.6 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 OAG37706.1 - 4.2e-10 39.7 0.6 1.8e-07 31.1 0.2 2.4 2 1 1 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OAG37706.1 - 2.9e-07 29.9 2.1 6.6e-05 22.2 1.3 2.1 2 0 0 2 2 2 2 FAD binding domain GIDA PF01134.22 OAG37706.1 - 2.2e-05 23.7 0.1 0.005 16.0 0.1 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A NAD_binding_8 PF13450.6 OAG37706.1 - 0.00011 22.3 0.5 0.00029 21.0 0.5 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAG37706.1 - 0.00055 19.3 0.0 0.00089 18.6 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAG37706.1 - 0.00081 19.9 0.2 0.0016 18.9 0.2 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 OAG37706.1 - 0.0013 18.1 0.8 0.0021 17.5 0.8 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 OAG37706.1 - 0.0014 17.9 0.0 0.0082 15.4 0.0 1.9 2 0 0 2 2 2 1 Thi4 family ApbA PF02558.16 OAG37706.1 - 0.002 17.8 0.2 0.0052 16.4 0.1 1.7 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA Lycopene_cycl PF05834.12 OAG37706.1 - 0.0033 16.5 0.5 0.0059 15.7 0.5 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein 3HCDH_N PF02737.18 OAG37706.1 - 0.017 15.0 0.0 0.028 14.3 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ThiF PF00899.21 OAG37706.1 - 0.019 14.3 0.0 0.04 13.3 0.0 1.4 1 0 0 1 1 1 0 ThiF family HI0933_like PF03486.14 OAG37706.1 - 0.026 13.2 0.2 0.038 12.7 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein UDPG_MGDP_dh_N PF03721.14 OAG37706.1 - 0.06 12.9 0.1 0.096 12.2 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AlaDh_PNT_C PF01262.21 OAG37706.1 - 0.14 11.4 0.2 0.26 10.6 0.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 OAG37706.1 - 0.16 12.1 0.0 0.29 11.2 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase PAP_assoc PF03828.19 OAG37707.1 - 4.7e-17 61.9 0.1 1.2e-16 60.7 0.1 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 OAG37707.1 - 2e-07 31.2 0.0 3.7e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 OAG37707.1 - 0.0013 18.8 0.0 0.0025 17.9 0.0 1.4 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase CALM_bind PF16025.5 OAG37708.1 - 0.14 12.6 5.1 0.32 11.5 5.1 1.6 1 0 0 1 1 1 0 Calcium-dependent calmodulin binding Zwint PF15556.6 OAG37708.1 - 0.56 9.7 4.6 0.84 9.1 4.6 1.2 1 0 0 1 1 1 0 ZW10 interactor GFO_IDH_MocA PF01408.22 OAG37709.1 - 1.7e-18 67.6 0.0 2.8e-18 66.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 OAG37709.1 - 1.4e-08 34.7 0.2 1.4e-07 31.5 0.0 2.4 3 0 0 3 3 3 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 OAG37709.1 - 0.011 16.4 0.0 0.019 15.6 0.0 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.24 OAG37709.1 - 0.1 13.0 0.0 0.18 12.3 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Redoxin PF08534.10 OAG37709.1 - 0.11 12.3 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Redoxin MFS_1 PF07690.16 OAG37710.1 - 1.2e-35 123.0 24.3 1.7e-35 122.6 23.3 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily YfhO PF09586.10 OAG37710.1 - 0.18 10.0 5.5 0.049 11.9 1.7 1.9 3 0 0 3 3 3 0 Bacterial membrane protein YfhO DUF485 PF04341.12 OAG37710.1 - 0.97 9.4 4.2 14 5.7 0.2 3.7 3 0 0 3 3 3 0 Protein of unknown function, DUF485 DUF2427 PF10348.9 OAG37710.1 - 4.3 7.2 7.9 4 7.3 0.1 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF2427) Bot1p PF12298.8 OAG37711.1 - 1.6e-46 158.6 0.2 1.6e-46 158.6 0.2 1.9 2 0 0 2 2 2 1 Eukaryotic mitochondrial regulator protein Glyco_hydro_43 PF04616.14 OAG37711.1 - 9.6e-28 97.3 0.0 1.4e-27 96.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Dynactin_p22 PF07426.11 OAG37713.1 - 0.00097 19.0 0.4 0.00097 19.0 0.4 2.3 2 1 0 2 2 2 1 Dynactin subunit p22 HALZ PF02183.18 OAG37713.1 - 2.7 8.3 5.8 4.5 7.6 0.4 2.4 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF4140 PF13600.6 OAG37713.1 - 4.2 7.9 8.9 2.2 8.8 0.5 3.0 3 1 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) SH3_1 PF00018.28 OAG37714.1 - 1.5e-09 37.3 0.3 5.5e-09 35.5 0.1 1.9 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 OAG37714.1 - 7.5e-07 28.9 0.0 1.3e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 OAG37714.1 - 1.1e-05 25.1 0.0 1.9e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain TMEM220 PF15071.6 OAG37714.1 - 0.008 16.9 3.4 0.015 16.0 3.4 1.6 1 1 0 1 1 1 1 Transmembrane family 220, helix YhhN PF07947.14 OAG37714.1 - 0.0082 15.8 11.4 0.012 15.2 11.4 1.2 1 0 0 1 1 1 1 YhhN family DUF2569 PF10754.9 OAG37714.1 - 0.099 13.1 9.3 0.2 12.1 9.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2569) DUF1129 PF06570.11 OAG37714.1 - 5.1 6.5 11.0 0.11 11.9 4.3 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) MARVEL PF01284.23 OAG37715.1 - 4.2e-10 39.8 5.0 6.5e-10 39.2 5.0 1.3 1 0 0 1 1 1 1 Membrane-associating domain RRM_1 PF00076.22 OAG37716.1 - 3.7e-33 113.1 0.3 3.9e-17 61.8 0.0 3.3 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OAG37716.1 - 0.00053 20.0 0.0 0.1 12.8 0.0 2.5 2 1 0 2 2 2 1 RNA recognition motif RRM_5 PF13893.6 OAG37716.1 - 0.0011 18.5 0.0 0.56 9.8 0.0 3.0 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.15 OAG37716.1 - 0.0016 18.4 0.8 1 9.4 0.1 2.4 2 0 0 2 2 2 2 DbpA RNA binding domain PHM7_cyt PF14703.6 OAG37716.1 - 0.0051 17.1 0.1 7.3 6.8 0.0 3.3 2 2 1 3 3 3 1 Cytosolic domain of 10TM putative phosphate transporter DUF4783 PF16022.5 OAG37716.1 - 0.02 15.1 0.0 0.23 11.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4783) Limkain-b1 PF11608.8 OAG37716.1 - 0.072 13.2 0.2 21 5.2 0.0 2.7 3 0 0 3 3 3 0 Limkain b1 DUF4944 PF16302.5 OAG37716.1 - 0.1 12.6 0.3 33 4.5 0.0 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4944) DUF1743 PF08489.11 OAG37716.1 - 0.11 12.5 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1743) API5 PF05918.11 OAG37716.1 - 0.89 8.3 4.0 1.3 7.7 4.0 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) FXMRP1_C_core PF12235.8 OAG37716.1 - 2.1 9.0 7.9 0.39 11.4 3.5 2.2 2 0 0 2 2 2 0 Fragile X-related 1 protein core C terminal Aldedh PF00171.22 OAG37717.1 - 4.1e-179 595.9 0.1 4.6e-179 595.7 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Fungal_trans PF04082.18 OAG37718.1 - 1.2e-25 90.1 0.1 2e-25 89.4 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain GMC_oxred_N PF00732.19 OAG37719.1 - 1.4e-54 185.4 0.0 1.9e-54 185.0 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAG37719.1 - 1e-33 116.9 0.0 1.6e-33 116.2 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 OAG37719.1 - 1.4e-06 27.7 0.6 0.0047 16.1 0.6 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 OAG37719.1 - 0.00071 18.7 0.3 0.0012 18.0 0.3 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 OAG37719.1 - 0.00093 19.4 0.3 0.0033 17.6 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAG37719.1 - 0.0047 16.5 2.0 0.011 15.4 2.0 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 OAG37719.1 - 0.0077 15.5 0.1 0.015 14.6 0.1 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 OAG37719.1 - 0.013 14.8 0.0 0.67 9.2 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAG37719.1 - 0.034 13.4 0.0 0.056 12.7 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OAG37719.1 - 0.057 12.5 0.5 0.75 8.8 0.1 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A adh_short_C2 PF13561.6 OAG37720.1 - 3.5e-67 226.4 1.2 3.9e-67 226.2 1.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG37720.1 - 6.2e-40 136.7 0.1 7.5e-40 136.5 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG37720.1 - 1.4e-11 44.7 0.3 1.7e-11 44.3 0.3 1.3 1 0 0 1 1 1 1 KR domain Fungal_trans PF04082.18 OAG37721.1 - 3.2e-16 59.2 0.0 5.2e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.18 OAG37722.1 - 1.4e-09 37.4 0.5 3.5e-09 36.1 0.2 1.8 1 1 1 2 2 2 1 Fungal specific transcription factor domain Dymeclin PF09742.9 OAG37722.1 - 0.088 11.2 1.5 0.15 10.4 0.4 1.7 1 1 1 2 2 2 0 Dyggve-Melchior-Clausen syndrome protein Sugar_tr PF00083.24 OAG37723.1 - 9.3e-92 308.2 29.2 1.1e-91 308.0 29.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG37723.1 - 1.8e-20 73.2 65.5 5.9e-18 64.9 37.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily FMO-like PF00743.19 OAG37724.1 - 4.3e-16 58.4 0.0 3.2e-13 48.9 0.0 3.8 3 1 0 3 3 3 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OAG37724.1 - 9.5e-12 45.0 0.1 4.2e-11 42.9 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAG37724.1 - 3.2e-11 43.0 0.0 6.5e-08 32.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG37724.1 - 2.6e-08 33.4 0.0 6.1e-05 22.3 0.0 3.8 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 OAG37724.1 - 1.1e-06 28.2 0.0 0.00015 21.1 0.0 3.0 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAG37724.1 - 0.00055 19.9 0.5 0.014 15.4 0.0 2.7 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.24 OAG37724.1 - 0.012 15.2 3.6 0.24 10.9 0.0 3.1 2 1 0 3 3 3 0 FAD dependent oxidoreductase HI0933_like PF03486.14 OAG37724.1 - 0.1 11.3 0.3 0.6 8.7 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein M60-like_N PF17291.2 OAG37724.1 - 0.11 12.4 0.0 0.37 10.7 0.0 1.8 2 0 0 2 2 2 0 N-terminal domain of M60-like peptidases Tubulin_2 PF13809.6 OAG37724.1 - 0.2 10.8 0.0 0.39 9.8 0.0 1.5 1 0 0 1 1 1 0 Tubulin like eIF-3c_N PF05470.12 OAG37724.1 - 0.23 9.7 0.6 4.6 5.4 0.0 2.0 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Peptidase_M3_N PF08439.10 OAG37724.1 - 0.48 10.7 1.6 1.2 9.5 1.6 1.7 1 0 0 1 1 1 0 Oligopeptidase F Striatin PF08232.12 OAG37725.1 - 4.7e-05 24.0 3.0 4.7e-05 24.0 3.0 2.4 3 0 0 3 3 3 1 Striatin family BBP1_C PF15272.6 OAG37725.1 - 0.018 14.9 0.1 0.018 14.9 0.1 1.8 3 0 0 3 3 3 0 Spindle pole body component BBP1, C-terminal DUF3987 PF13148.6 OAG37725.1 - 0.042 12.9 1.6 0.076 12.0 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) DUF724 PF05266.14 OAG37725.1 - 0.05 13.4 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF724) CALCOCO1 PF07888.11 OAG37725.1 - 0.17 10.7 4.5 0.036 13.0 1.3 1.4 2 0 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like Pox_A_type_inc PF04508.12 OAG37725.1 - 0.42 10.6 4.6 0.094 12.6 0.9 2.0 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat PhyH PF05721.13 OAG37726.1 - 9.3e-26 91.4 0.0 1.3e-25 90.9 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF3400 PF11880.8 OAG37726.1 - 0.064 12.8 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3400) HsdM_N PF12161.8 OAG37726.1 - 0.16 12.6 0.1 3.5 8.2 0.1 2.5 2 1 0 2 2 2 0 HsdM N-terminal domain Glyco_transf_28 PF03033.20 OAG37727.1 - 4.5e-19 68.9 0.1 1.7e-18 67.0 0.1 2.0 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 OAG37727.1 - 4.3e-07 29.1 0.0 6.8e-07 28.4 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 OAG37727.1 - 0.00056 19.9 0.0 0.0014 18.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain T5orf172 PF10544.9 OAG37728.1 - 2.4e-23 82.6 1.0 1e-22 80.6 1.0 2.1 1 0 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 OAG37728.1 - 1.2e-21 77.1 0.4 2.7e-21 76.0 0.4 1.6 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 CCDC144C PF14915.6 OAG37729.1 - 0.14 11.2 9.4 0.27 10.3 9.4 1.4 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region AMP-binding PF00501.28 OAG37730.1 - 4e-71 239.8 0.0 9.3e-71 238.6 0.0 1.6 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG37730.1 - 6.9e-13 49.4 0.4 2.4e-07 31.7 0.0 2.6 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain Thump_like PF18096.1 OAG37730.1 - 0.089 12.7 0.0 0.24 11.3 0.0 1.7 1 0 0 1 1 1 0 THUMP domain-like Fungal_trans PF04082.18 OAG37731.1 - 4.7e-27 94.7 0.3 4.7e-27 94.7 0.3 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain AAA_12 PF13087.6 OAG37732.1 - 5.1e-30 104.6 0.0 8.4e-30 103.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 OAG37732.1 - 3.3e-23 82.8 0.0 2.2e-22 80.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 OAG37732.1 - 1.9e-13 50.6 0.0 2e-06 27.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 OAG37732.1 - 4.7e-12 46.5 0.0 9.9e-12 45.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 OAG37732.1 - 1.3e-05 25.1 0.0 0.86 9.3 0.0 3.3 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.6 OAG37732.1 - 2.9e-05 23.8 0.0 7.8e-05 22.4 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain DUF2075 PF09848.9 OAG37732.1 - 9.8e-05 21.7 0.9 0.28 10.4 0.0 3.3 3 1 0 3 3 3 2 Uncharacterized conserved protein (DUF2075) UvrD-helicase PF00580.21 OAG37732.1 - 0.00071 19.2 0.0 0.0046 16.5 0.0 2.1 1 1 1 2 2 2 1 UvrD/REP helicase N-terminal domain Helicase_RecD PF05127.14 OAG37732.1 - 0.0015 18.5 0.3 0.78 9.6 0.1 2.4 2 0 0 2 2 2 2 Helicase AAA_22 PF13401.6 OAG37732.1 - 0.0019 18.5 0.0 0.075 13.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OAG37732.1 - 0.0042 17.5 0.1 0.01 16.2 0.1 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 OAG37732.1 - 0.029 14.5 0.1 0.2 11.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain adh_short PF00106.25 OAG37734.1 - 1.1e-15 57.6 0.0 3e-15 56.2 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG37734.1 - 5.9e-09 35.8 0.0 8.6e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG37734.1 - 4.5e-07 30.0 0.0 6.5e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 KR domain RraA-like PF03737.15 OAG37735.1 - 3.2e-37 128.0 0.0 4.4e-37 127.5 0.0 1.2 1 0 0 1 1 1 1 Aldolase/RraA CfAFP PF05264.11 OAG37735.1 - 0.15 12.1 0.0 0.21 11.5 0.0 1.2 1 0 0 1 1 1 0 Choristoneura fumiferana antifreeze protein (CfAFP) ABM PF03992.16 OAG37736.1 - 5.8e-08 32.7 0.0 0.0002 21.4 0.0 3.0 3 0 0 3 3 3 2 Antibiotic biosynthesis monooxygenase Glyco_tranf_2_3 PF13641.6 OAG37737.1 - 9.9e-19 68.1 0.0 1.5e-18 67.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 OAG37737.1 - 3.1e-14 53.4 0.8 3.1e-14 53.4 0.8 3.2 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 OAG37737.1 - 2.1e-13 50.4 0.0 3.9e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Cellulose_synt PF03552.14 OAG37737.1 - 3.3e-10 39.1 4.3 3.4e-07 29.2 3.4 2.5 1 1 2 3 3 3 2 Cellulose synthase Glyco_transf_21 PF13506.6 OAG37737.1 - 8.7e-10 38.3 0.0 1.4e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Chitin_synth_2 PF03142.15 OAG37737.1 - 0.029 13.0 4.4 0.059 12.0 0.2 2.8 2 1 1 3 3 3 0 Chitin synthase Glyco_hydro_12 PF01670.16 OAG37738.1 - 8.7e-17 61.8 3.2 6.7e-16 58.9 3.2 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 12 Ldi PF18566.1 OAG37739.1 - 5.5e-82 275.8 0.0 8.9e-82 275.1 0.0 1.3 1 0 0 1 1 1 1 Linalool dehydratase/isomerase Aldedh PF00171.22 OAG37740.1 - 1.1e-149 498.9 0.0 1.3e-149 498.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family TarH PF02203.15 OAG37740.1 - 0.11 12.4 0.1 0.21 11.5 0.1 1.4 1 0 0 1 1 1 0 Tar ligand binding domain homologue DUF1487 PF07368.11 OAG37740.1 - 0.22 10.9 0.2 0.62 9.5 0.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1487) HEAT_2 PF13646.6 OAG37741.1 - 1.3e-09 38.3 10.4 0.18 12.2 0.0 7.5 6 2 2 8 8 8 5 HEAT repeats HEAT PF02985.22 OAG37741.1 - 1e-07 31.6 22.9 1.8 9.0 0.1 10.7 11 0 0 11 11 11 2 HEAT repeat HEAT_EZ PF13513.6 OAG37741.1 - 4.4e-05 23.9 9.9 17 6.0 0.0 7.9 5 1 0 6 6 6 2 HEAT-like repeat Adaptin_N PF01602.20 OAG37741.1 - 0.00031 19.5 0.3 1.7 7.1 0.0 4.6 3 2 0 4 4 4 1 Adaptin N terminal region CLASP_N PF12348.8 OAG37741.1 - 0.00035 20.2 1.3 2.3 7.7 0.0 4.3 3 1 1 4 4 4 2 CLASP N terminal Condensin2nSMC PF12422.8 OAG37741.1 - 0.019 15.2 0.4 12 6.0 0.0 4.4 4 0 0 4 4 4 0 Condensin II non structural maintenance of chromosomes subunit RTP1_C1 PF10363.9 OAG37741.1 - 0.028 14.6 0.2 52 4.1 0.0 4.2 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 Vac14_Fab1_bd PF12755.7 OAG37741.1 - 0.1 13.2 0.0 0.91 10.2 0.0 2.8 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region DUF3336 PF11815.8 OAG37742.1 - 1.1e-25 89.9 0.0 2e-25 89.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 OAG37742.1 - 4e-20 72.9 0.0 1.1e-19 71.5 0.0 1.7 2 0 0 2 2 2 1 Patatin-like phospholipase mRNA_triPase PF02940.15 OAG37743.1 - 2.7e-52 177.7 0.0 3.9e-52 177.1 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain RPN2_C PF18004.1 OAG37744.1 - 1.2e-55 187.8 7.4 1.2e-55 187.8 7.4 2.4 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 OAG37744.1 - 7e-33 111.4 10.2 2.6e-09 37.1 0.0 8.5 8 0 0 8 8 8 6 Proteasome/cyclosome repeat HEAT_2 PF13646.6 OAG37744.1 - 1.9e-19 69.8 0.7 3.4e-14 53.0 0.1 4.5 2 1 2 4 4 4 3 HEAT repeats HEAT PF02985.22 OAG37744.1 - 7.7e-07 28.8 0.0 1.6 9.2 0.0 5.9 5 0 0 5 5 5 1 HEAT repeat HEAT_EZ PF13513.6 OAG37744.1 - 2.5e-06 27.9 1.5 0.0001 22.7 0.1 4.2 3 1 1 4 4 4 2 HEAT-like repeat Cnd1 PF12717.7 OAG37744.1 - 0.058 13.4 0.2 1.1 9.2 0.0 2.7 1 1 1 2 2 2 0 non-SMC mitotic condensation complex subunit 1 HEAT_PBS PF03130.16 OAG37744.1 - 0.1 13.3 1.8 1.7 9.6 0.1 3.6 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat Ribosomal_S8 PF00410.19 OAG37745.1 - 4.4e-15 55.8 0.0 4.1e-14 52.6 0.0 2.1 1 1 0 1 1 1 1 Ribosomal protein S8 Amidoligase_2 PF12224.8 OAG37746.1 - 2.6e-13 50.2 2.0 2.2e-06 27.6 0.4 3.0 2 1 0 2 2 2 2 Putative amidoligase enzyme MFS_1 PF07690.16 OAG37747.1 - 2.5e-24 85.9 29.1 2.5e-24 85.9 29.1 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily PBP PF01161.20 OAG37749.1 - 3.9e-11 43.4 0.1 6.6e-11 42.7 0.1 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein SSP160 PF06933.11 OAG37749.1 - 0.86 7.7 19.5 1.2 7.2 19.5 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 NUDE_C PF04880.13 OAG37749.1 - 9.9 6.6 7.9 16 5.9 7.9 1.3 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region F-box-like PF12937.7 OAG37750.1 - 0.00015 21.6 0.7 0.00085 19.2 0.1 2.3 2 0 0 2 2 2 1 F-box-like DZR PF12773.7 OAG37750.1 - 0.17 11.9 3.8 0.37 10.8 3.8 1.6 1 0 0 1 1 1 0 Double zinc ribbon ADH_zinc_N PF00107.26 OAG37751.1 - 2e-18 66.6 0.1 1.2e-17 64.1 0.0 2.4 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAG37751.1 - 5.3e-12 46.9 0.0 1.1e-11 45.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG37751.1 - 5.7e-07 29.4 0.0 8.3e-06 25.7 0.0 2.5 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain SnoaL_2 PF12680.7 OAG37751.1 - 0.0017 19.0 0.1 0.0042 17.7 0.1 1.7 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 OAG37751.1 - 0.023 15.1 0.0 0.051 14.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) Fungal_trans PF04082.18 OAG37752.1 - 0.0023 17.0 0.0 0.0052 15.9 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 OAG37753.1 - 3.2e-24 85.5 25.7 4.6e-24 85.0 21.3 2.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Phage_holin_2_4 PF16082.5 OAG37753.1 - 0.11 12.3 0.6 4 7.3 0.0 2.8 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like DUF4748 PF15932.5 OAG37753.1 - 0.12 12.1 3.4 0.5 10.2 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4748) Glyco_hydro_125 PF06824.11 OAG37754.1 - 3.4e-18 65.8 0.1 9.8e-18 64.2 0.0 1.7 2 1 1 3 3 3 1 Metal-independent alpha-mannosidase (GH125) ADH_zinc_N PF00107.26 OAG37755.1 - 4.1e-17 62.4 0.2 7.8e-17 61.5 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG37755.1 - 9.9e-16 57.6 1.7 2.4e-15 56.3 1.7 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 OAG37755.1 - 0.00017 22.7 0.0 0.00035 21.6 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 OAG37755.1 - 0.00063 19.1 1.1 0.00063 19.1 1.1 1.8 2 1 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 OAG37755.1 - 0.028 13.8 0.1 0.044 13.2 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PucR PF07905.11 OAG37755.1 - 0.047 14.0 0.0 0.089 13.1 0.0 1.5 1 0 0 1 1 1 0 Purine catabolism regulatory protein-like family NAD_binding_7 PF13241.6 OAG37755.1 - 0.054 13.9 0.4 0.095 13.2 0.4 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding ACP_syn_III_C PF08541.10 OAG37755.1 - 0.15 12.3 0.5 0.4 10.9 0.1 1.9 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ThiF PF00899.21 OAG37755.1 - 0.17 11.2 2.4 0.19 11.1 1.6 1.5 1 1 0 1 1 1 0 ThiF family APG5 PF04106.12 OAG37757.1 - 3.7e-59 200.1 0.0 4.7e-59 199.7 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg5 DUF3602 PF12223.8 OAG37759.1 - 1.6e-07 31.8 10.2 0.00039 21.0 3.9 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF3602) KdgM PF06178.13 OAG37759.1 - 0.0091 15.6 0.1 0.012 15.2 0.1 1.1 1 0 0 1 1 1 1 Oligogalacturonate-specific porin protein (KdgM) DUF1686 PF07937.11 OAG37760.1 - 0.044 13.7 0.8 4 7.3 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1686) GST_N_3 PF13417.6 OAG37761.1 - 5.5e-13 49.1 0.0 1.1e-12 48.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAG37761.1 - 1.6e-10 40.9 0.1 2.8e-10 40.0 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 OAG37761.1 - 1.2e-05 25.5 0.0 2.4e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 OAG37761.1 - 2.7e-05 24.3 0.0 4.7e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain FmiP_Thoc5 PF09766.9 OAG37762.1 - 1.8e-23 83.4 11.0 2.3e-23 83.1 11.0 1.1 1 0 0 1 1 1 1 Fms-interacting protein/Thoc5 TolA_bind_tri PF16331.5 OAG37762.1 - 0.026 14.6 5.4 0.026 14.6 5.4 2.2 3 0 0 3 3 3 0 TolA binding protein trimerisation Laminin_II PF06009.12 OAG37762.1 - 3.7 7.6 8.6 9.1 6.3 0.4 2.1 2 0 0 2 2 2 0 Laminin Domain II Med30 PF11315.8 OAG37762.1 - 5 7.3 11.3 0.64 10.2 3.4 2.6 2 1 1 3 3 3 0 Mediator complex subunit 30 Methyltransf_25 PF13649.6 OAG37763.1 - 3.3e-15 56.5 0.0 7e-15 55.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG37763.1 - 4.2e-14 53.1 0.0 1.2e-13 51.6 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAG37763.1 - 1.5e-12 47.7 0.0 2.7e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG37763.1 - 3.5e-11 43.6 0.0 7.8e-11 42.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG37763.1 - 1.9e-09 37.5 0.0 2.9e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAG37763.1 - 4.3e-07 29.5 0.0 6.3e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_24 PF13578.6 OAG37763.1 - 0.00015 22.7 0.0 0.00033 21.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OAG37763.1 - 0.0034 17.0 0.0 0.0054 16.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_8 PF05148.15 OAG37763.1 - 0.008 16.0 0.0 0.16 11.8 0.0 2.2 1 1 0 1 1 1 1 Hypothetical methyltransferase UPF0020 PF01170.18 OAG37763.1 - 0.05 13.3 0.0 0.086 12.5 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 CMAS PF02353.20 OAG37763.1 - 0.061 12.6 0.0 0.097 11.9 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.17 OAG37763.1 - 0.063 12.7 0.0 0.29 10.6 0.0 2.0 1 1 0 1 1 1 0 Putative methyltransferase TPMT PF05724.11 OAG37763.1 - 0.074 12.7 0.0 0.19 11.3 0.0 1.6 1 1 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) HlyIII PF03006.20 OAG37764.1 - 5.9e-61 206.0 22.7 7.3e-61 205.7 22.7 1.1 1 0 0 1 1 1 1 Haemolysin-III related Tex_N PF09371.10 OAG37764.1 - 0.035 13.8 0.0 0.061 13.0 0.0 1.3 1 0 0 1 1 1 0 Tex-like protein N-terminal domain MFS_1 PF07690.16 OAG37765.1 - 6.5e-23 81.2 37.8 6.5e-23 81.2 37.8 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily FixS PF03597.15 OAG37765.1 - 0.88 9.3 4.4 3.8 7.3 0.5 3.1 2 0 0 2 2 2 0 Cytochrome oxidase maturation protein cbb3-type NAD_binding_8 PF13450.6 OAG37766.1 - 3.1e-12 46.5 0.0 1.3e-11 44.5 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAG37766.1 - 2.1e-08 33.8 0.0 5.2e-07 29.2 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG37766.1 - 8e-08 31.9 0.0 7.5e-06 25.4 0.3 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 OAG37766.1 - 2.4e-07 29.6 0.0 2.9e-05 22.7 0.0 2.4 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 OAG37766.1 - 6.3e-07 28.8 0.0 0.0002 20.6 0.0 3.0 3 1 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 OAG37766.1 - 3.3e-05 23.9 0.0 0.0049 16.9 0.0 3.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.24 OAG37766.1 - 0.00048 19.8 0.0 0.0049 16.5 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Bac_luciferase PF00296.20 OAG37767.1 - 1.4e-57 195.5 0.0 1.8e-57 195.1 0.0 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase Fungal_trans_2 PF11951.8 OAG37768.1 - 4.6e-06 25.7 0.1 6.2e-06 25.3 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 OAG37772.1 - 4.5e-16 58.7 28.2 5e-11 42.1 23.9 2.6 2 1 0 2 2 2 2 Major Facilitator Superfamily Glycos_transf_2 PF00535.26 OAG37772.1 - 0.00018 21.4 0.0 0.00033 20.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 OAG37772.1 - 0.00088 19.2 0.0 0.0079 16.1 0.0 2.2 1 1 0 1 1 1 1 Glycosyltransferase like family 2 OATP PF03137.20 OAG37772.1 - 0.00089 17.7 3.4 0.0033 15.8 1.2 2.5 2 1 1 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family Glyco_transf_21 PF13506.6 OAG37772.1 - 0.0023 17.4 0.0 0.005 16.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_5 PF13712.6 OAG37772.1 - 0.16 11.6 0.0 0.28 10.9 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase like family Herpes_pp38 PF04846.13 OAG37772.1 - 0.18 11.7 4.2 4.2 7.4 0.5 3.2 2 0 0 2 2 2 0 Herpesvirus pp38 phosphoprotein DUF1100 PF06500.11 OAG37773.1 - 6e-09 35.2 0.0 0.00032 19.6 0.0 2.1 2 0 0 2 2 2 2 Alpha/beta hydrolase of unknown function (DUF1100) Peptidase_S15 PF02129.18 OAG37773.1 - 3.8e-08 33.3 0.0 5.9e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.20 OAG37773.1 - 7.1e-06 25.8 0.0 3.5e-05 23.6 0.0 1.9 1 1 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 OAG37773.1 - 2.5e-05 23.8 0.0 4.9e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 OAG37773.1 - 0.0025 17.5 0.0 0.17 11.5 0.0 2.2 1 1 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAG37773.1 - 0.0068 15.7 0.2 0.3 10.3 0.2 2.2 1 1 0 2 2 2 1 Serine aminopeptidase, S33 BAAT_C PF08840.11 OAG37773.1 - 0.13 12.2 0.0 0.23 11.3 0.0 1.4 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF4286 PF14114.6 OAG37774.1 - 0.075 13.5 0.0 10 6.7 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4286) Peptidase_M20 PF01546.28 OAG37775.1 - 1.5e-08 34.6 0.2 2.6e-08 33.8 0.2 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 OAG37775.1 - 9.5e-07 28.7 0.1 3e-06 27.1 0.1 1.8 1 0 0 1 1 1 1 Peptidase dimerisation domain Ferritin_2 PF13668.6 OAG37777.1 - 1.3e-12 48.1 0.0 2.3e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 Ferritin-like domain Spuma_A9PTase PF03539.14 OAG37777.1 - 0.043 14.0 0.1 0.069 13.3 0.1 1.2 1 0 0 1 1 1 0 Spumavirus aspartic protease (A9) TrfA PF07042.11 OAG37778.1 - 0.0087 15.1 0.0 0.015 14.4 0.0 1.3 1 0 0 1 1 1 1 TrfA protein ZapB PF06005.12 OAG37778.1 - 0.047 14.1 0.5 0.09 13.2 0.5 1.4 1 0 0 1 1 1 0 Cell division protein ZapB bZIP_1 PF00170.21 OAG37780.1 - 4.6e-08 33.0 14.6 6.7e-08 32.5 14.6 1.3 1 0 0 1 1 1 1 bZIP transcription factor SNF2_N PF00176.23 OAG37781.1 - 6.8e-64 215.8 0.0 1.3e-63 214.9 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-C3HC4_3 PF13920.6 OAG37781.1 - 6.8e-08 32.3 8.4 2.2e-07 30.6 8.4 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OAG37781.1 - 2.2e-07 30.6 10.3 2.2e-07 30.6 10.3 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAG37781.1 - 9.4e-07 29.1 10.8 2.7e-06 27.6 10.8 1.9 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 OAG37781.1 - 2.7e-06 27.1 9.7 2.7e-06 27.1 9.7 1.9 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 OAG37781.1 - 3.8e-06 26.7 10.4 1.5e-05 24.8 10.4 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Helicase_C PF00271.31 OAG37781.1 - 5.2e-06 26.8 0.2 2.3e-05 24.7 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.6 OAG37781.1 - 0.00032 20.6 9.7 0.00032 20.6 9.7 2.0 2 0 0 2 2 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 OAG37781.1 - 0.0043 17.0 5.9 0.0043 17.0 5.9 2.5 2 1 1 3 3 2 1 RING-type zinc-finger zf-UDP PF14569.6 OAG37781.1 - 0.049 13.7 2.5 0.19 11.8 2.5 2.0 1 0 0 1 1 1 0 Zinc-binding RING-finger DASH_Dad4 PF08650.10 OAG37781.1 - 0.14 12.1 0.5 0.62 10.1 0.5 2.1 1 0 0 1 1 1 0 DASH complex subunit Dad4 zf-P11 PF03854.14 OAG37781.1 - 0.49 10.1 6.7 1.1 9.0 6.7 1.5 1 0 0 1 1 1 0 P-11 zinc finger zf-C3HC4_4 PF15227.6 OAG37781.1 - 1.1 9.5 15.4 0.04 14.1 9.2 1.9 2 0 0 2 2 1 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 OAG37781.1 - 3.8 7.9 11.4 15 5.9 11.4 2.1 1 1 0 1 1 1 0 RING-H2 zinc finger domain Tup_N PF08581.10 OAG37781.1 - 7.3 7.0 9.7 0.19 12.1 0.7 3.0 3 0 0 3 3 2 0 Tup N-terminal Abhydrolase_6 PF12697.7 OAG37782.1 - 5.2e-10 40.3 0.5 5.2e-10 40.3 0.5 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAG37782.1 - 2.3e-07 30.7 0.0 4.6e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAG37782.1 - 4.7e-07 29.3 0.0 1.2e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 OAG37782.1 - 0.0059 16.5 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold F-box PF00646.33 OAG37782.1 - 0.04 13.8 0.0 0.15 12.0 0.0 2.1 2 0 0 2 2 2 0 F-box domain Raffinose_syn PF05691.12 OAG37784.1 - 6.7e-57 192.8 0.8 1.9e-54 184.7 0.8 3.0 1 1 0 1 1 1 1 Raffinose synthase or seed imbibition protein Sip1 Melibiase PF02065.18 OAG37784.1 - 0.084 11.8 0.2 0.13 11.2 0.2 1.2 1 0 0 1 1 1 0 Melibiase ABC_tran PF00005.27 OAG37786.1 - 4e-47 160.2 1.1 2.5e-22 79.9 0.0 3.0 3 0 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 OAG37786.1 - 2.4e-21 75.5 6.1 2.4e-21 75.5 6.1 4.0 4 1 1 5 5 3 1 ABC transporter AAA_21 PF13304.6 OAG37786.1 - 2.4e-13 50.6 9.9 0.0043 16.9 0.1 5.1 4 1 0 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OAG37786.1 - 7.3e-11 41.9 0.3 0.027 13.9 0.0 4.5 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 OAG37786.1 - 1.1e-06 29.0 0.0 0.0063 16.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 OAG37786.1 - 3.5e-06 27.0 0.2 0.046 13.6 0.1 2.9 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OAG37786.1 - 6.6e-06 26.2 0.0 0.047 13.8 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 OAG37786.1 - 6.7e-06 26.6 1.4 0.059 13.8 0.2 2.9 3 0 0 3 3 2 2 AAA ATPase domain AAA_23 PF13476.6 OAG37786.1 - 9.5e-06 26.2 15.9 0.032 14.7 0.0 5.1 5 0 0 5 5 5 2 AAA domain AAA_29 PF13555.6 OAG37786.1 - 1.1e-05 25.1 0.2 0.15 11.8 0.0 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_30 PF13604.6 OAG37786.1 - 0.0001 22.1 0.1 0.017 14.8 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 OAG37786.1 - 0.00016 22.2 4.0 0.27 11.8 0.0 3.2 4 0 0 4 4 2 2 AAA domain AAA_33 PF13671.6 OAG37786.1 - 0.00017 21.8 1.2 0.37 11.0 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_24 PF13479.6 OAG37786.1 - 0.00025 20.8 2.5 0.57 9.9 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA PF00004.29 OAG37786.1 - 0.00098 19.6 0.1 0.87 10.0 0.1 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 OAG37786.1 - 0.0018 18.1 13.2 0.3 10.8 0.0 4.7 4 1 0 4 4 4 2 AAA ATPase domain AAA_28 PF13521.6 OAG37786.1 - 0.0019 18.5 5.1 0.11 12.8 0.1 3.0 3 0 0 3 3 2 1 AAA domain NACHT PF05729.12 OAG37786.1 - 0.0026 17.7 0.6 0.85 9.5 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_14 PF13173.6 OAG37786.1 - 0.0027 17.7 0.0 3.9 7.5 0.0 3.1 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 OAG37786.1 - 0.0039 17.6 0.0 2.1 8.8 0.0 2.6 2 0 0 2 2 2 1 RNA helicase MobB PF03205.14 OAG37786.1 - 0.014 15.3 0.0 0.4 10.6 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.12 OAG37786.1 - 0.015 14.6 1.0 2.8 7.2 0.0 2.9 3 0 0 3 3 3 0 Zeta toxin NTPase_1 PF03266.15 OAG37786.1 - 0.017 15.0 0.0 1.6 8.6 0.0 2.8 2 0 0 2 2 2 0 NTPase AAA_27 PF13514.6 OAG37786.1 - 0.021 14.4 3.8 3.5 7.2 0.0 3.5 4 0 0 4 4 3 0 AAA domain MeaB PF03308.16 OAG37786.1 - 0.023 13.7 3.5 2.5 7.0 0.1 2.9 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Roc PF08477.13 OAG37786.1 - 0.033 14.4 0.1 7.1 6.9 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 OAG37786.1 - 0.035 13.7 2.7 0.98 9.0 0.3 2.8 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 OAG37786.1 - 0.044 13.3 0.0 5.5 6.5 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region Rad17 PF03215.15 OAG37786.1 - 0.045 13.7 0.1 3.4 7.6 0.0 3.0 2 1 1 3 3 3 0 Rad17 P-loop domain ATP-synt_ab PF00006.25 OAG37786.1 - 0.05 13.3 0.0 1.3 8.6 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_5 PF07728.14 OAG37786.1 - 0.058 13.4 0.1 7.9 6.5 0.0 2.8 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) TsaE PF02367.17 OAG37786.1 - 0.061 13.3 0.0 10 6.1 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Dynamin_N PF00350.23 OAG37786.1 - 0.076 13.1 9.4 1.8 8.6 0.0 3.7 3 1 0 4 4 3 0 Dynamin family NB-ARC PF00931.22 OAG37786.1 - 0.08 12.1 0.0 14 4.8 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain Arf PF00025.21 OAG37786.1 - 0.27 10.7 1.1 2.9 7.3 0.0 2.6 3 0 0 3 3 3 0 ADP-ribosylation factor family DUF87 PF01935.17 OAG37786.1 - 1.3 9.1 13.0 1.7 8.7 0.0 4.5 5 0 0 5 5 4 0 Helicase HerA, central domain SGL PF08450.12 OAG37787.1 - 0.00017 21.3 0.8 0.23 11.0 0.1 2.6 2 1 1 3 3 3 2 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 OAG37787.1 - 0.00032 20.6 0.3 2.3 8.4 0.0 3.9 3 0 0 3 3 3 2 NHL repeat Lactonase PF10282.9 OAG37787.1 - 0.074 12.3 0.2 2.1 7.5 0.0 2.2 1 1 0 2 2 2 0 Lactonase, 7-bladed beta-propeller Mitofilin PF09731.9 OAG37789.1 - 8.8e-141 470.8 25.7 2.1e-119 400.2 21.7 2.1 2 0 0 2 2 2 2 Mitochondrial inner membrane protein DUF4559 PF15112.6 OAG37789.1 - 0.024 14.3 7.1 0.043 13.5 7.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) HsbA PF12296.8 OAG37789.1 - 1.1 9.7 6.6 0.075 13.5 0.6 2.2 2 0 0 2 2 2 0 Hydrophobic surface binding protein A Focal_AT PF03623.13 OAG37789.1 - 5.9 6.9 7.0 3.4 7.7 1.0 2.4 1 1 1 2 2 2 0 Focal adhesion targeting region Pescadillo_N PF06732.11 OAG37790.1 - 8.4e-121 402.7 0.2 8.4e-121 402.7 0.2 1.7 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT_2 PF16589.5 OAG37790.1 - 1.8e-05 25.0 0.1 0.0002 21.7 0.1 2.6 1 1 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 OAG37790.1 - 0.00052 20.3 0.0 0.005 17.2 0.0 2.5 2 1 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 OAG37790.1 - 0.13 12.6 0.2 0.8 10.0 0.2 2.4 1 1 0 1 1 1 0 DNA ligase 3 BRCT domain PIG-U PF06728.13 OAG37791.1 - 9.1e-104 347.5 24.8 1.1e-103 347.3 24.8 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U 8TM_micro PF17028.5 OAG37791.1 - 0.35 10.5 4.0 0.98 9.1 4.0 1.7 1 1 0 1 1 1 0 8TM Microsporidial transmembrane domain Acetyltransf_1 PF00583.25 OAG37792.1 - 3.1e-15 56.4 0.0 4.5e-15 55.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OAG37792.1 - 7.5e-09 35.9 0.1 1.1e-08 35.3 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OAG37792.1 - 1.9e-08 34.3 0.0 2.7e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAG37792.1 - 5.7e-05 23.0 0.0 0.00011 22.2 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 OAG37792.1 - 0.028 14.5 0.0 0.052 13.7 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_15 PF17013.5 OAG37792.1 - 0.14 11.6 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 Putative acetyl-transferase Aldedh PF00171.22 OAG37793.1 - 1.2e-165 551.5 0.4 1.3e-165 551.4 0.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Dynamin_N PF00350.23 OAG37794.1 - 7e-09 36.0 0.0 2.7e-07 30.8 0.0 2.7 1 1 1 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 OAG37794.1 - 3.1e-07 30.5 0.0 0.026 14.6 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OAG37794.1 - 0.0016 18.4 3.0 0.0067 16.3 0.0 2.7 3 0 0 3 3 3 1 RsgA GTPase ABC_tran PF00005.27 OAG37794.1 - 0.018 15.6 0.6 0.059 13.9 0.0 2.1 2 0 0 2 2 2 0 ABC transporter AAA_16 PF13191.6 OAG37794.1 - 0.028 14.8 4.9 0.19 12.1 1.5 3.6 2 1 0 2 2 2 0 AAA ATPase domain P22_AR_N PF10547.9 OAG37794.1 - 0.035 14.4 1.4 2.8 8.3 0.8 2.6 2 0 0 2 2 2 0 P22_AR N-terminal domain DIL PF01843.19 OAG37794.1 - 0.043 14.1 0.9 1.1 9.6 0.0 2.8 3 0 0 3 3 3 0 DIL domain AIG1 PF04548.16 OAG37794.1 - 0.073 12.4 0.0 0.17 11.2 0.0 1.6 1 0 0 1 1 1 0 AIG1 family MerR-DNA-bind PF09278.11 OAG37794.1 - 0.11 13.0 2.5 2.4 8.8 0.2 3.2 2 0 0 2 2 2 0 MerR, DNA binding CTD_bind PF04818.13 OAG37794.1 - 4.6 8.2 4.8 14 6.6 0.0 2.9 3 0 0 3 3 3 0 RNA polymerase II-binding domain. Ank_4 PF13637.6 OAG37795.1 - 3e-75 247.7 1.7 8.4e-11 42.2 0.0 12.5 2 2 12 14 14 14 14 Ankyrin repeats (many copies) Ank_2 PF12796.7 OAG37795.1 - 1.9e-73 243.1 1.4 1.5e-13 51.1 0.0 7.1 2 2 4 7 7 7 7 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OAG37795.1 - 8.4e-61 194.7 0.1 0.00089 19.5 0.0 15.2 15 0 0 15 15 15 14 Ankyrin repeat Ank_5 PF13857.6 OAG37795.1 - 7.6e-58 191.8 9.2 2.7e-08 33.9 0.0 11.5 3 2 9 12 12 12 12 Ankyrin repeats (many copies) Ank PF00023.30 OAG37795.1 - 4.2e-54 178.8 10.9 0.00096 19.5 0.0 14.9 14 1 1 15 15 15 13 Ankyrin repeat Shigella_OspC PF06128.11 OAG37795.1 - 7.2e-05 22.7 0.4 0.1 12.3 0.1 5.0 5 2 3 8 8 8 1 Shigella flexneri OspC protein DUF4646 PF15496.6 OAG37795.1 - 0.016 15.8 0.5 6.5 7.4 0.0 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4646) NAD_binding_10 PF13460.6 OAG37796.1 - 2.8e-15 56.7 1.3 5.5e-15 55.7 1.3 1.6 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 OAG37796.1 - 3.7e-12 46.3 0.2 5.2e-12 45.8 0.2 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 OAG37796.1 - 1.9e-08 34.1 0.1 5e-06 26.2 0.1 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 OAG37796.1 - 4.5e-05 23.5 0.3 7.2e-05 22.9 0.3 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 OAG37796.1 - 0.00089 19.5 0.3 0.0016 18.7 0.3 1.4 1 0 0 1 1 1 1 TrkA-N domain KR PF08659.10 OAG37796.1 - 0.0018 18.2 0.1 0.0027 17.6 0.1 1.3 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 OAG37796.1 - 0.0034 16.5 0.3 0.049 12.7 0.2 2.1 2 0 0 2 2 2 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 OAG37796.1 - 0.0035 16.5 0.1 0.012 14.8 0.1 1.8 1 1 1 2 2 2 1 Polysaccharide biosynthesis protein F420_oxidored PF03807.17 OAG37796.1 - 0.0036 17.9 0.2 0.0099 16.4 0.2 1.8 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent DapB_N PF01113.20 OAG37796.1 - 0.0089 16.1 0.3 0.018 15.2 0.3 1.5 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus ApbA PF02558.16 OAG37796.1 - 0.0093 15.6 0.1 0.017 14.8 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Sacchrp_dh_NADP PF03435.18 OAG37796.1 - 0.0096 16.2 0.3 0.016 15.4 0.3 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 OAG37796.1 - 0.019 15.4 0.2 0.033 14.6 0.2 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain LpxI_N PF17930.1 OAG37796.1 - 0.082 12.8 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 LpxI N-terminal domain GDP_Man_Dehyd PF16363.5 OAG37796.1 - 0.088 12.2 0.3 11 5.4 0.0 2.6 2 1 1 3 3 3 0 GDP-mannose 4,6 dehydratase Fungal_trans_2 PF11951.8 OAG37797.1 - 8.7e-56 189.4 0.1 1.2e-55 188.9 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aldedh PF00171.22 OAG37798.1 - 4.2e-171 569.5 0.3 5.1e-171 569.2 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF3606 PF12244.8 OAG37798.1 - 0.14 12.1 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) FMO-like PF00743.19 OAG37799.1 - 2.9e-18 65.6 0.0 8.1e-18 64.1 0.0 1.6 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OAG37799.1 - 3.4e-18 65.9 0.0 2.8e-17 62.9 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG37799.1 - 1.4e-10 40.9 0.1 3.8e-09 36.2 0.0 2.4 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 OAG37799.1 - 7e-10 38.6 0.0 2.1e-08 33.8 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAG37799.1 - 2.5e-06 27.3 0.3 0.008 15.8 0.0 2.3 1 1 1 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAG37799.1 - 6.7e-06 26.2 0.0 0.00034 20.8 0.1 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain 2-Hacid_dh_C PF02826.19 OAG37799.1 - 0.0044 16.4 0.0 0.0097 15.3 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 OAG37799.1 - 0.008 16.3 0.0 0.041 13.9 0.0 2.1 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 OAG37799.1 - 0.024 13.9 2.8 0.76 9.0 0.0 3.0 3 1 1 4 4 4 0 FAD binding domain FAD_binding_2 PF00890.24 OAG37799.1 - 0.026 13.6 0.0 0.047 12.8 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.6 OAG37799.1 - 0.1 12.6 0.1 33 4.4 0.0 3.2 3 0 0 3 3 3 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 OAG37799.1 - 0.15 12.6 0.2 37 5.0 0.1 2.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAG37799.1 - 0.17 11.1 0.0 0.42 9.8 0.0 1.6 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 OAG37799.1 - 0.33 9.6 0.7 1.1 7.9 0.1 2.1 3 0 0 3 3 3 0 HI0933-like protein Sugar_tr PF00083.24 OAG37800.1 - 1.3e-75 255.0 19.8 1.7e-75 254.7 19.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG37800.1 - 2.1e-26 92.7 34.4 1.2e-20 73.8 10.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily 4HBT PF03061.22 OAG37802.1 - 0.00012 22.3 0.0 0.00022 21.5 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily MRP-S23 PF10484.9 OAG37802.1 - 0.1 12.9 0.1 0.15 12.4 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein S23 DUF1856 PF08983.10 OAG37802.1 - 0.15 12.3 0.0 0.27 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1856) Ank_2 PF12796.7 OAG37804.1 - 5.6e-32 110.2 4.2 8.5e-10 39.1 0.0 6.1 1 1 6 8 8 8 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAG37804.1 - 2.2e-29 101.4 3.8 5.5e-10 39.6 0.0 8.6 5 3 2 8 8 8 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 OAG37804.1 - 1.8e-26 91.9 10.5 1.8e-05 24.9 0.0 7.7 7 1 1 8 8 8 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG37804.1 - 1.7e-22 77.0 9.9 0.019 15.4 0.0 9.7 10 0 0 10 10 8 6 Ankyrin repeat Ank PF00023.30 OAG37804.1 - 5.2e-19 67.8 6.4 0.0038 17.6 0.0 9.4 10 0 0 10 10 8 4 Ankyrin repeat SPRY PF00622.28 OAG37804.1 - 1.1e-13 51.3 0.0 3.7e-13 49.6 0.0 2.0 2 0 0 2 2 1 1 SPRY domain NACHT PF05729.12 OAG37804.1 - 2.9e-09 37.1 0.1 1e-08 35.3 0.0 2.0 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 OAG37804.1 - 5.2e-07 30.2 0.2 2.5e-06 28.0 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain KAP_NTPase PF07693.14 OAG37804.1 - 1.5e-06 27.7 1.6 0.0066 15.7 1.6 2.4 1 1 0 1 1 1 1 KAP family P-loop domain DUF4211 PF13926.6 OAG37804.1 - 4e-05 23.7 0.0 0.071 13.2 0.0 2.8 2 0 0 2 2 2 2 Domain of unknown function (DUF4211) NB-ARC PF00931.22 OAG37804.1 - 0.0011 18.2 0.0 0.0011 18.2 0.0 1.7 2 0 0 2 2 2 1 NB-ARC domain AAA_22 PF13401.6 OAG37804.1 - 0.031 14.6 1.6 0.086 13.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF2791 PF10923.8 OAG37804.1 - 0.032 13.1 0.3 0.073 11.9 0.3 1.6 1 1 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) ABC_tran PF00005.27 OAG37804.1 - 0.074 13.6 3.6 0.27 11.7 0.0 2.8 2 0 0 2 2 2 0 ABC transporter ATPase_2 PF01637.18 OAG37804.1 - 0.12 12.3 0.9 0.35 10.7 0.1 2.1 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA PF00004.29 OAG37804.1 - 0.13 12.7 0.2 1.1 9.7 0.2 2.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.18 OAG37804.1 - 0.16 11.3 1.6 0.19 11.0 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_14 PF13173.6 OAG37804.1 - 0.44 10.6 2.7 3.9 7.5 0.2 3.3 2 1 0 2 2 2 0 AAA domain YebO PF13974.6 OAG37804.1 - 1.8 8.7 5.9 6.3 7.0 4.6 2.6 2 0 0 2 2 2 0 YebO-like protein PDE4_UCR PF18100.1 OAG37804.1 - 3.3 8.4 5.0 1.1 9.9 0.1 2.7 3 0 0 3 3 3 0 Phosphodiesterase 4 upstream conserved regions (UCR) Acid_PPase PF12689.7 OAG37805.1 - 1.4e-56 191.0 0.0 1.6e-56 190.7 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase Pyr_redox_2 PF07992.14 OAG37806.1 - 2.8e-09 36.6 0.0 0.0058 15.9 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG37806.1 - 0.0057 16.9 0.0 0.014 15.6 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 OAG37806.1 - 0.021 14.8 0.0 0.11 12.4 0.0 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 OAG37806.1 - 0.044 13.0 0.0 0.093 12.0 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 OAG37806.1 - 0.21 10.2 0.0 0.34 9.6 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein DUF1793 PF08760.11 OAG37807.1 - 3e-70 236.0 0.3 8.1e-70 234.6 0.3 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) DUF4965 PF16335.5 OAG37807.1 - 3.3e-61 206.0 0.4 1e-47 162.0 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4965) DUF5127 PF17168.4 OAG37807.1 - 2.1e-47 161.8 1.0 3.3e-47 161.2 1.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4964 PF16334.5 OAG37807.1 - 4.6e-05 22.9 0.0 9.5e-05 21.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4964) SBF PF01758.16 OAG37808.1 - 9.4e-39 133.1 1.6 9.4e-39 133.1 1.6 2.4 2 2 1 3 3 3 1 Sodium Bile acid symporter family SBF_like PF13593.6 OAG37808.1 - 2e-09 37.2 6.4 2e-09 37.2 6.4 1.9 1 1 0 2 2 2 1 SBF-like CPA transporter family (DUF4137) bZIP_1 PF00170.21 OAG37809.1 - 0.38 10.9 6.6 0.49 10.5 5.0 1.8 1 1 0 2 2 2 0 bZIP transcription factor Acyl-CoA_dh_1 PF00441.24 OAG37810.1 - 7.2e-29 100.9 0.3 1.2e-28 100.2 0.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 OAG37810.1 - 9.1e-20 70.7 0.0 1.6e-19 69.8 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 OAG37810.1 - 1.7e-15 57.7 0.0 4.8e-15 56.2 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 OAG37810.1 - 2.1e-11 44.2 0.5 3.5e-11 43.5 0.5 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain SWIRM-assoc_3 PF16498.5 OAG37810.1 - 0.12 12.7 0.8 0.71 10.2 0.0 2.6 2 1 1 3 3 3 0 SWIRM-associated domain at the C-terminal CN_hydrolase PF00795.22 OAG37811.1 - 6e-37 127.4 0.2 8.3e-37 126.9 0.2 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Mito_carr PF00153.27 OAG37812.1 - 3e-72 238.6 1.2 5.3e-25 87.2 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PT-VENN PF04829.13 OAG37812.1 - 0.72 10.0 0.0 0.72 10.0 0.0 2.3 3 0 0 3 3 3 0 Pre-toxin domain with VENN motif Pkinase PF00069.25 OAG37813.1 - 1.3e-21 77.2 0.0 1.9e-21 76.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG37813.1 - 4.8e-10 39.2 0.0 1e-09 38.1 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 OAG37813.1 - 2.2e-06 27.8 0.5 0.0061 16.5 0.0 2.7 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OAG37813.1 - 5.1e-06 25.5 0.0 7.8e-06 24.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OAG37813.1 - 0.0023 17.3 0.0 0.0034 16.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family ABC1 PF03109.16 OAG37813.1 - 0.014 15.6 0.0 0.029 14.6 0.0 1.4 1 0 0 1 1 1 0 ABC1 family HET PF06985.11 OAG37815.1 - 1.7e-34 119.3 0.0 5e-34 117.7 0.0 1.8 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Abhydrolase_1 PF00561.20 OAG37816.1 - 1.5e-18 67.4 0.0 3.4e-18 66.2 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 OAG37816.1 - 4.5e-17 62.1 0.0 9.4e-17 61.0 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein HMMR_N PF15905.5 OAG37817.1 - 0.00055 19.5 0.6 0.00084 18.9 0.6 1.4 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal AAA_13 PF13166.6 OAG37817.1 - 0.0015 17.3 0.3 0.0019 16.9 0.3 1.1 1 0 0 1 1 1 1 AAA domain DUF4407 PF14362.6 OAG37817.1 - 0.002 17.5 1.5 0.0034 16.8 1.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) FlaC_arch PF05377.11 OAG37817.1 - 0.04 14.3 3.5 6.7 7.2 0.0 3.9 2 2 2 4 4 4 0 Flagella accessory protein C (FlaC) Kre28 PF17097.5 OAG37817.1 - 0.063 12.2 2.5 0.1 11.6 0.1 2.1 2 0 0 2 2 2 0 Spindle pole body component MAD PF05557.13 OAG37817.1 - 0.068 11.5 10.3 0.03 12.7 1.3 2.1 2 0 0 2 2 2 0 Mitotic checkpoint protein DUF948 PF06103.11 OAG37817.1 - 0.1 12.9 0.8 0.43 10.9 0.1 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Mod_r PF07200.13 OAG37817.1 - 0.12 12.5 3.6 0.47 10.5 0.1 2.6 2 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Lipoprotein_7 PF01540.16 OAG37817.1 - 0.14 11.4 0.2 1.4 8.1 0.1 2.0 2 0 0 2 2 2 0 Adhesin lipoprotein CHASE3 PF05227.13 OAG37817.1 - 0.18 11.7 12.5 0.22 11.5 0.6 2.4 2 0 0 2 2 2 0 CHASE3 domain DUF1192 PF06698.11 OAG37817.1 - 0.19 11.8 0.1 0.19 11.8 0.1 3.4 4 0 0 4 4 3 0 Protein of unknown function (DUF1192) HIP1_clath_bdg PF16515.5 OAG37817.1 - 0.2 12.3 8.9 0.52 10.9 0.2 2.8 2 1 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Spc7 PF08317.11 OAG37817.1 - 0.22 10.4 12.2 1.6 7.5 0.5 2.3 1 1 0 2 2 2 0 Spc7 kinetochore protein DUF1664 PF07889.12 OAG37817.1 - 0.29 11.2 4.5 2.2 8.3 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Tropomyosin_1 PF12718.7 OAG37817.1 - 0.5 10.5 11.1 0.038 14.1 3.3 2.3 2 1 0 2 2 2 0 Tropomyosin like DUF641 PF04859.12 OAG37817.1 - 0.59 10.5 10.7 2.3 8.5 1.2 3.3 3 1 1 4 4 3 0 Plant protein of unknown function (DUF641) ABC_tran_CTD PF16326.5 OAG37817.1 - 0.77 10.0 0.0 0.77 10.0 0.0 3.9 3 1 1 4 4 4 0 ABC transporter C-terminal domain OmpH PF03938.14 OAG37817.1 - 1.1 9.6 8.5 1.9 8.8 3.4 2.8 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) DUF4200 PF13863.6 OAG37817.1 - 1.1 9.7 11.5 3.3 8.2 2.8 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) DUF724 PF05266.14 OAG37817.1 - 1.1 9.0 4.7 2.1 8.2 1.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Bap31_Bap29_C PF18035.1 OAG37817.1 - 1.5 8.9 6.9 0.97 9.5 0.4 3.2 2 2 0 3 3 3 0 Bap31/Bap29 cytoplasmic coiled-coil domain GAS PF13851.6 OAG37817.1 - 1.5 8.1 9.8 2.6 7.4 0.5 2.7 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding Fez1 PF06818.15 OAG37817.1 - 1.6 9.1 11.4 6.3 7.2 11.1 2.0 1 1 0 1 1 1 0 Fez1 PRKG1_interact PF15898.5 OAG37817.1 - 1.6 9.7 10.7 6.2 7.8 0.8 2.9 2 1 0 2 2 2 0 cGMP-dependent protein kinase interacting domain UPF0242 PF06785.11 OAG37817.1 - 1.7 8.7 5.1 3.9 7.5 4.3 1.9 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus BRE1 PF08647.11 OAG37817.1 - 2 8.5 8.8 13 6.0 2.2 2.9 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase Cep57_CLD_2 PF14197.6 OAG37817.1 - 2.1 8.5 16.9 4.4 7.5 9.1 3.7 1 1 1 2 2 1 0 Centrosome localisation domain of PPC89 CENP-F_leu_zip PF10473.9 OAG37817.1 - 3 7.9 14.6 0.12 12.4 1.4 2.9 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Atg14 PF10186.9 OAG37817.1 - 3.2 6.8 6.7 9.1 5.3 2.4 2.5 2 1 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 S4 PF01479.25 OAG37818.1 - 9.7e-12 44.4 0.9 9.7e-12 44.4 0.9 2.5 3 0 0 3 3 3 1 S4 domain Ribosomal_S4 PF00163.19 OAG37818.1 - 7.5e-06 26.8 0.2 1.6e-05 25.7 0.2 1.6 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain Ribosomal_L21e PF01157.18 OAG37819.1 - 3.9e-48 161.5 7.3 6.4e-48 160.8 5.6 1.8 2 0 0 2 2 2 1 Ribosomal protein L21e LRS4 PF10422.9 OAG37819.1 - 0.016 14.8 0.0 0.02 14.5 0.0 1.1 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 RdRP PF05183.12 OAG37820.1 - 4.2e-184 613.5 0.0 5.5e-184 613.1 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase RRM_1 PF00076.22 OAG37820.1 - 0.015 15.1 0.0 0.066 13.0 0.0 2.1 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Hypoth_Ymh PF09509.10 OAG37820.1 - 0.026 14.4 0.1 0.15 12.0 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (Hypoth_ymh) FGE-sulfatase PF03781.16 OAG37820.1 - 0.13 11.8 0.1 0.25 10.9 0.1 1.4 1 0 0 1 1 1 0 Sulfatase-modifying factor enzyme 1 Cupin_2 PF07883.11 OAG37821.1 - 5.5e-22 77.3 2.2 1.1e-11 44.3 0.5 2.4 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.19 OAG37821.1 - 6.5e-05 22.9 2.3 0.13 12.1 0.0 2.3 2 0 0 2 2 2 2 AraC-like ligand binding domain Cupin_1 PF00190.22 OAG37821.1 - 0.00029 20.5 0.1 0.58 9.8 0.0 2.5 2 1 0 2 2 2 2 Cupin Cupin_3 PF05899.12 OAG37821.1 - 0.00087 18.9 0.1 0.38 10.5 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) MannoseP_isomer PF01050.18 OAG37821.1 - 0.0014 18.6 0.0 0.35 10.7 0.0 2.2 2 0 0 2 2 2 2 Mannose-6-phosphate isomerase CENP-C_C PF11699.8 OAG37821.1 - 0.0031 17.7 0.0 0.1 12.8 0.0 2.2 2 0 0 2 2 2 1 Mif2/CENP-C like DMSP_lyase PF16867.5 OAG37821.1 - 0.011 15.4 0.4 1.6 8.3 0.0 2.1 2 0 0 2 2 2 0 Dimethlysulfonioproprionate lyase Fungal_trans PF04082.18 OAG37822.1 - 6.2e-17 61.5 1.4 1e-16 60.8 1.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cyclase PF04199.13 OAG37823.1 - 2e-14 54.0 0.1 4.1e-14 53.0 0.1 1.3 1 1 0 1 1 1 1 Putative cyclase Abhydrolase_3 PF07859.13 OAG37824.1 - 1.6e-52 178.5 0.1 1.9e-52 178.2 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 OAG37824.1 - 1.5e-14 53.7 0.0 1.8e-14 53.4 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_2 PF02230.16 OAG37824.1 - 0.002 18.0 0.1 0.0048 16.7 0.0 1.6 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 OAG37824.1 - 0.12 11.8 0.0 0.29 10.6 0.0 1.7 1 1 0 1 1 1 0 Prolyl oligopeptidase family UPF0227 PF05728.12 OAG37824.1 - 0.15 12.0 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) ComA PF02679.15 OAG37824.1 - 0.15 11.5 0.0 0.25 10.8 0.0 1.2 1 0 0 1 1 1 0 (2R)-phospho-3-sulfolactate synthase (ComA) PGA_cap PF09587.10 OAG37824.1 - 0.16 11.4 0.3 1.1 8.6 0.0 2.0 2 0 0 2 2 2 0 Bacterial capsule synthesis protein PGA_cap Pyr_redox_3 PF13738.6 OAG37825.1 - 2.6e-13 49.9 0.0 2.5e-10 40.1 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 OAG37825.1 - 1.3e-10 40.3 0.0 1.1e-07 30.7 0.0 2.5 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 OAG37825.1 - 1.1e-09 37.9 0.0 3.2e-07 29.9 0.0 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG37825.1 - 7.8e-07 29.2 0.4 6.4e-06 26.3 0.1 2.6 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.20 OAG37825.1 - 7.1e-06 26.1 0.0 0.077 13.1 0.1 2.4 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase Lycopene_cycl PF05834.12 OAG37825.1 - 9.7e-06 24.9 0.0 0.0026 16.9 0.0 3.6 3 1 0 3 3 3 1 Lycopene cyclase protein DAO PF01266.24 OAG37825.1 - 9.6e-05 22.1 4.5 0.00032 20.4 1.0 2.8 2 1 1 3 3 3 1 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.19 OAG37825.1 - 0.00023 20.6 0.1 0.002 17.5 0.0 2.3 3 0 0 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 OAG37825.1 - 0.0004 19.6 0.2 0.00059 19.0 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 OAG37825.1 - 0.00044 20.3 0.2 0.082 12.9 0.1 3.3 3 0 0 3 3 3 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 OAG37825.1 - 0.0011 18.1 0.0 0.63 9.1 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) TrkA_N PF02254.18 OAG37825.1 - 0.0026 18.0 0.4 1.3 9.3 0.2 3.4 3 0 0 3 3 3 1 TrkA-N domain GMC_oxred_N PF00732.19 OAG37825.1 - 0.0089 15.4 0.0 0.016 14.6 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox PF00070.27 OAG37825.1 - 0.011 16.2 0.8 1.7 9.2 1.1 2.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DltD PF04914.12 OAG37825.1 - 0.011 15.1 0.1 0.034 13.5 0.0 1.7 2 0 0 2 2 2 0 DltD protein Thi4 PF01946.17 OAG37825.1 - 0.017 14.4 0.1 0.035 13.3 0.1 1.5 1 0 0 1 1 1 0 Thi4 family NAD_binding_2 PF03446.15 OAG37825.1 - 0.056 13.6 0.0 0.19 11.9 0.0 1.9 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase FAD_binding_3 PF01494.19 OAG37825.1 - 0.11 11.7 1.4 0.23 10.7 0.8 1.8 2 0 0 2 2 2 0 FAD binding domain F420_oxidored PF03807.17 OAG37825.1 - 0.14 12.7 0.1 13 6.4 0.0 2.6 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent ThiF PF00899.21 OAG37825.1 - 0.15 11.4 0.5 4.5 6.5 0.1 2.3 2 0 0 2 2 2 0 ThiF family CMD PF02627.20 OAG37827.1 - 1.3e-16 60.4 0.0 1.2e-08 34.8 0.0 2.3 2 0 0 2 2 2 2 Carboxymuconolactone decarboxylase family IF2_N PF04760.15 OAG37827.1 - 0.083 12.7 1.8 1.6 8.6 0.4 2.5 2 0 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region Pyr_redox_2 PF07992.14 OAG37828.1 - 1.4e-10 40.9 0.0 4.9e-06 26.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 OAG37828.1 - 3.8e-09 35.5 0.1 1.3e-07 30.4 0.0 2.8 3 1 0 3 3 3 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OAG37828.1 - 4.2e-09 36.5 0.0 1.1e-08 35.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 OAG37828.1 - 1.7e-07 31.4 0.4 1.7e-05 24.8 0.0 3.4 3 1 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.24 OAG37828.1 - 6.8e-05 22.6 0.0 0.082 12.5 0.0 2.8 2 1 1 3 3 3 2 FAD dependent oxidoreductase K_oxygenase PF13434.6 OAG37828.1 - 0.00011 21.5 0.0 0.013 14.7 0.0 3.2 2 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 OAG37828.1 - 0.13 11.5 0.0 2 7.6 0.0 2.3 2 0 0 2 2 2 0 Thi4 family adh_short PF00106.25 OAG37829.1 - 1.2e-57 194.6 0.5 1.5e-57 194.2 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG37829.1 - 3.9e-56 190.2 1.1 6.1e-56 189.6 1.1 1.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG37829.1 - 8.7e-17 61.6 0.3 1.5e-16 60.8 0.2 1.4 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 OAG37829.1 - 0.0083 15.6 0.1 0.013 15.0 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family ATP_bind_2 PF03668.15 OAG37829.1 - 0.076 12.3 0.1 0.11 11.8 0.1 1.2 1 0 0 1 1 1 0 P-loop ATPase protein family Aldedh PF00171.22 OAG37830.1 - 2.6e-155 517.5 0.1 2.9e-155 517.3 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 OAG37830.1 - 3.8e-05 22.9 0.1 8.1e-05 21.8 0.1 1.4 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.11 OAG37830.1 - 0.028 13.9 0.0 4.7 6.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) ADH_N PF08240.12 OAG37831.1 - 5.4e-25 87.4 1.4 9.2e-25 86.6 1.4 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG37831.1 - 1.6e-21 76.6 0.0 2.6e-21 76.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAG37831.1 - 1.2e-05 26.3 0.0 2.9e-05 25.1 0.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 OAG37831.1 - 0.11 12.4 0.0 0.33 10.9 0.0 1.8 2 0 0 2 2 2 0 N-terminal domain of oxidoreductase Cyclase PF04199.13 OAG37833.1 - 1.1e-13 51.6 0.0 1.5e-13 51.1 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase Connexin50 PF03509.14 OAG37833.1 - 0.19 12.5 0.0 0.33 11.8 0.0 1.4 1 0 0 1 1 1 0 Gap junction alpha-8 protein (Cx50) AtuA PF07287.11 OAG37834.1 - 3e-125 417.6 0.0 4.4e-125 417.1 0.0 1.2 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA adh_short PF00106.25 OAG37834.1 - 3.4e-51 173.5 0.9 4.8e-51 173.0 0.2 1.6 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG37834.1 - 5.2e-49 166.9 0.2 2.1e-48 164.9 0.3 1.8 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG37834.1 - 4e-11 43.2 1.0 7.5e-11 42.3 1.0 1.3 1 0 0 1 1 1 1 KR domain FAD_binding_2 PF00890.24 OAG37835.1 - 3.9e-62 210.7 0.1 5.3e-62 210.2 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAG37835.1 - 7e-11 42.3 0.4 1.2e-10 41.6 0.4 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 OAG37835.1 - 3.4e-09 36.6 0.0 8.4e-09 35.3 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 OAG37835.1 - 1.1e-05 24.8 0.5 3.5e-05 23.2 0.4 1.8 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.14 OAG37835.1 - 6.3e-05 22.3 0.1 0.001 18.3 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG37835.1 - 0.0003 20.9 1.2 0.00099 19.3 1.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 OAG37835.1 - 0.0021 16.8 0.7 0.0021 16.8 0.7 1.5 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 OAG37835.1 - 0.046 12.8 0.4 0.074 12.1 0.4 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A TRI12 PF06609.13 OAG37836.1 - 7.3e-37 127.1 21.5 8.7e-37 126.8 21.5 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG37836.1 - 6.2e-20 71.4 44.8 6.2e-20 71.4 44.8 2.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG37836.1 - 2.5e-16 59.6 8.2 2.5e-16 59.6 8.2 3.0 2 1 0 3 3 3 1 Sugar (and other) transporter p450 PF00067.22 OAG37837.1 - 2.2e-67 227.8 0.0 2.7e-67 227.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Acyl_transf_3 PF01757.22 OAG37838.1 - 2e-36 125.8 27.0 3.4e-36 125.0 27.0 1.4 1 1 0 1 1 1 1 Acyltransferase family AA_permease_2 PF13520.6 OAG37839.1 - 7.3e-22 77.8 13.5 9.1e-22 77.5 13.5 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAG37839.1 - 1.2e-07 30.7 12.8 1.4e-07 30.5 12.8 1.1 1 0 0 1 1 1 1 Amino acid permease YwiC PF14256.6 OAG37839.1 - 0.24 11.7 5.4 0.26 11.6 1.8 2.2 2 1 0 2 2 2 0 YwiC-like protein Sugar_tr PF00083.24 OAG37841.1 - 8.5e-125 417.1 26.7 1e-124 416.9 26.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG37841.1 - 4.9e-19 68.5 24.1 4.9e-19 68.5 24.1 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2530 PF10745.9 OAG37841.1 - 0.96 9.7 6.1 1.9 8.7 2.2 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2530) LapA_dom PF06305.11 OAG37841.1 - 4 7.3 6.6 12 5.8 0.3 3.7 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain SGL PF08450.12 OAG37842.1 - 0.0019 17.8 0.0 0.92 9.0 0.0 2.3 1 1 0 2 2 2 2 SMP-30/Gluconolactonase/LRE-like region MFS_1 PF07690.16 OAG37843.1 - 5.6e-24 84.7 26.1 5.6e-24 84.7 26.1 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily adh_short PF00106.25 OAG37844.1 - 4.9e-25 88.1 0.4 1.2e-12 47.7 0.1 2.1 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAG37844.1 - 3.1e-19 69.5 0.1 2.6e-10 40.3 0.1 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG37844.1 - 3.1e-07 30.5 0.1 5.2e-05 23.2 0.0 2.4 1 1 1 2 2 2 2 KR domain Epimerase PF01370.21 OAG37844.1 - 9.5e-05 22.0 0.0 0.00012 21.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 OAG37844.1 - 0.061 13.6 0.0 0.098 12.9 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain SnoaL_2 PF12680.7 OAG37845.1 - 0.015 15.9 0.0 0.021 15.4 0.0 1.3 1 0 0 1 1 1 0 SnoaL-like domain EthD PF07110.11 OAG37846.1 - 2.2e-21 76.8 0.1 2.7e-21 76.5 0.1 1.1 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 OAG37846.1 - 3e-06 27.7 0.0 4.1e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Methylmuconolactone methyl-isomerase p450 PF00067.22 OAG37847.1 - 1.4e-61 208.6 0.0 1.9e-61 208.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Stirrup PF09061.6 OAG37847.1 - 0.14 12.4 0.1 0.4 10.9 0.0 1.8 2 0 0 2 2 2 0 Stirrup EthD PF07110.11 OAG37848.1 - 7.2e-18 65.5 0.1 9.3e-18 65.2 0.1 1.1 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 OAG37848.1 - 4e-05 24.0 0.0 5.8e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Methylmuconolactone methyl-isomerase Fungal_trans PF04082.18 OAG37850.1 - 1.2e-18 67.1 0.1 2e-18 66.4 0.1 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Isochorismatase PF00857.20 OAG37851.1 - 2.6e-20 73.3 0.0 3e-20 73.1 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family BLM10_mid PF16507.5 OAG37852.1 - 3.6e-208 692.5 0.0 5.7e-208 691.8 0.0 1.3 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 OAG37852.1 - 1.4e-28 98.6 0.0 4.8e-28 96.9 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) BLM10_N PF16547.5 OAG37852.1 - 7e-23 80.7 0.0 1.6e-22 79.5 0.0 1.7 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, N-terminal HEAT PF02985.22 OAG37852.1 - 0.00045 20.2 0.1 2 8.9 0.0 4.4 3 0 0 3 3 3 1 HEAT repeat CLASP_N PF12348.8 OAG37852.1 - 0.0034 17.0 0.2 0.67 9.5 0.0 2.9 2 0 0 2 2 2 1 CLASP N terminal HEAT_2 PF13646.6 OAG37852.1 - 0.014 15.8 0.1 3.3 8.2 0.0 4.2 4 0 0 4 4 4 0 HEAT repeats V_ATPase_I PF01496.19 OAG37853.1 - 3.2e-299 994.5 0.1 4.1e-299 994.2 0.1 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Ribosomal_L40e PF01020.17 OAG37853.1 - 1.3e-30 105.1 12.0 2.1e-30 104.3 12.0 1.4 1 0 0 1 1 1 1 Ribosomal L40e family ubiquitin PF00240.23 OAG37853.1 - 4.3e-30 103.3 0.4 8.8e-30 102.3 0.4 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 OAG37853.1 - 2.9e-12 46.2 0.3 8e-12 44.8 0.3 1.8 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 OAG37853.1 - 0.00064 20.1 0.1 0.0024 18.3 0.1 1.9 1 0 0 1 1 1 1 Ubiquitin-like domain CheZ PF04344.13 OAG37853.1 - 0.012 15.5 0.7 0.043 13.7 0.1 2.1 2 0 0 2 2 2 0 Chemotaxis phosphatase, CheZ Filament PF00038.21 OAG37853.1 - 0.013 15.1 2.4 1.3 8.6 0.5 2.3 2 0 0 2 2 2 0 Intermediate filament protein Ubiquitin_5 PF18037.1 OAG37853.1 - 0.055 13.8 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-like domain TBK1_ULD PF18396.1 OAG37853.1 - 0.061 13.3 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain DUF5344 PF17279.2 OAG37853.1 - 0.12 12.9 0.3 30 5.3 0.0 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5344) Baculo_PEP_C PF04513.12 OAG37853.1 - 0.12 12.4 0.5 0.64 10.1 0.1 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DivIC PF04977.15 OAG37853.1 - 0.48 10.2 1.7 3.8 7.4 0.5 2.6 2 0 0 2 2 2 0 Septum formation initiator Yip1 PF04893.17 OAG37854.1 - 6.7e-11 42.2 13.9 1e-10 41.6 13.9 1.4 1 1 0 1 1 1 1 Yip1 domain YIF1 PF03878.15 OAG37854.1 - 0.02 14.4 2.6 0.16 11.5 2.6 2.1 1 1 0 1 1 1 0 YIF1 RabGAP-TBC PF00566.18 OAG37855.1 - 1.6e-11 44.3 0.9 2.1e-11 43.9 0.0 1.6 2 0 0 2 2 2 1 Rab-GTPase-TBC domain MMS1_N PF10433.9 OAG37856.1 - 2e-48 165.2 0.0 3.6e-47 161.1 0.0 2.2 2 0 0 2 2 2 2 Mono-functional DNA-alkylating methyl methanesulfonate N-term GTP_EFTU PF00009.27 OAG37857.1 - 3.5e-32 111.5 1.7 6.9e-32 110.6 0.0 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 OAG37857.1 - 5.7e-21 74.6 0.1 1.6e-20 73.2 0.1 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 OAG37857.1 - 1.5e-10 41.3 2.1 1.6e-09 38.0 0.0 3.2 3 0 0 3 3 3 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.6 OAG37857.1 - 3e-09 36.7 0.3 1.1e-08 34.8 0.3 2.0 1 1 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.23 OAG37857.1 - 7.5e-08 32.4 0.3 5.6e-06 26.4 0.0 3.4 3 0 0 3 3 3 1 50S ribosome-binding GTPase Roc PF08477.13 OAG37857.1 - 0.0004 20.6 0.0 0.0012 19.1 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 OAG37857.1 - 0.0018 18.1 0.0 0.008 16.0 0.0 2.1 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 OAG37857.1 - 0.1 12.5 0.3 1.6 8.6 0.2 2.9 2 1 0 2 2 2 0 RsgA GTPase p450 PF00067.22 OAG37858.1 - 2.3e-54 184.9 0.0 3.5e-54 184.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 TauD PF02668.16 OAG37859.1 - 1.5e-41 143.0 6.5 1.1e-34 120.5 1.9 2.2 1 1 1 2 2 2 2 Taurine catabolism dioxygenase TauD, TfdA family YebG PF07130.12 OAG37859.1 - 0.037 13.9 0.1 0.1 12.5 0.1 1.7 1 0 0 1 1 1 0 YebG protein ACOX PF01756.19 OAG37860.1 - 7.3e-38 129.9 0.2 1.6e-37 128.8 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 OAG37860.1 - 2.2e-23 83.2 0.5 4.4e-23 82.2 0.5 1.6 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 OAG37860.1 - 4.5e-08 33.2 0.0 8.9e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain NMO PF03060.15 OAG37861.1 - 8.8e-59 199.5 0.0 2.1e-58 198.3 0.0 1.5 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 OAG37861.1 - 6.5e-14 51.7 0.1 1.6e-06 27.3 0.3 2.1 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 OAG37861.1 - 0.0067 15.5 0.4 0.011 14.8 0.4 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase DUF1729 PF08354.10 OAG37861.1 - 0.014 14.3 0.0 0.021 13.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1729) NanE PF04131.14 OAG37861.1 - 0.075 12.2 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase adh_short PF00106.25 OAG37862.1 - 2.2e-28 99.1 0.0 3.2e-28 98.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG37862.1 - 2.9e-21 76.1 0.0 4.5e-21 75.5 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG37862.1 - 7.2e-06 26.0 0.0 0.00025 21.0 0.1 2.3 2 0 0 2 2 2 1 KR domain AlaDh_PNT_C PF01262.21 OAG37862.1 - 0.0012 18.2 0.9 0.0019 17.6 0.9 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain THF_DHG_CYH_C PF02882.19 OAG37862.1 - 0.024 13.9 0.2 0.046 13.0 0.0 1.5 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DeoC PF01791.9 OAG37862.1 - 0.05 13.2 0.5 0.072 12.7 0.1 1.4 2 0 0 2 2 2 0 DeoC/LacD family aldolase Methyltransf_31 PF13847.6 OAG37862.1 - 0.088 12.6 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Fungal_trans PF04082.18 OAG37863.1 - 7.1e-14 51.5 0.1 1e-13 51.0 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG37863.1 - 2.9e-05 24.1 8.6 2.9e-05 24.1 8.6 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_C42 PF05533.12 OAG37863.1 - 0.084 12.9 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Beet yellows virus-type papain-like endopeptidase C42 DUF4719 PF15843.5 OAG37863.1 - 0.094 12.8 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4719) adh_short_C2 PF13561.6 OAG37864.1 - 2.9e-68 229.9 1.1 3.3e-68 229.7 1.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG37864.1 - 4.2e-51 173.2 1.3 5e-51 173.0 1.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG37864.1 - 2.3e-13 50.5 2.0 3.2e-13 50.0 2.0 1.1 1 0 0 1 1 1 1 KR domain Ldh_1_N PF00056.23 OAG37864.1 - 0.027 14.5 0.4 0.045 13.8 0.4 1.3 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 OAG37864.1 - 0.21 11.5 1.7 0.16 11.8 0.2 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sugar_tr PF00083.24 OAG37865.1 - 2e-79 267.6 26.1 2.3e-79 267.4 26.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG37865.1 - 6.8e-23 81.2 53.4 2.2e-16 59.7 24.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Abhydrolase_3 PF07859.13 OAG37866.1 - 6.7e-30 104.5 0.0 8.8e-30 104.1 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 OAG37866.1 - 3e-10 39.5 0.0 4.7e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 OAG37866.1 - 0.083 12.4 0.1 6.9 6.1 0.1 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family COesterase PF00135.28 OAG37866.1 - 0.14 10.9 0.1 2.9 6.7 0.0 2.1 2 0 0 2 2 2 0 Carboxylesterase family ECH_1 PF00378.20 OAG37867.1 - 9.8e-39 133.2 0.0 1.8e-38 132.3 0.0 1.3 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAG37867.1 - 1.4e-26 93.8 0.0 2.2e-23 83.3 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase SPO22 PF08631.10 OAG37867.1 - 0.12 11.9 0.0 0.16 11.4 0.0 1.1 1 0 0 1 1 1 0 Meiosis protein SPO22/ZIP4 like FMO-like PF00743.19 OAG37868.1 - 1.8e-16 59.7 0.7 2.4e-14 52.7 0.2 2.5 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OAG37868.1 - 2.5e-10 40.5 0.1 3.5e-09 36.8 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 OAG37868.1 - 5.3e-09 35.7 0.0 1.2e-07 31.3 0.0 2.5 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 OAG37868.1 - 6.3e-05 22.4 0.1 0.00038 19.8 0.0 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAG37868.1 - 0.00019 20.7 0.0 0.00082 18.7 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAG37868.1 - 0.0029 17.6 0.2 0.3 11.0 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.17 OAG37868.1 - 0.039 13.2 0.1 12 5.1 0.0 2.7 3 0 0 3 3 3 0 Thi4 family Malic_M PF03949.15 OAG37868.1 - 0.069 12.4 0.1 0.28 10.4 0.1 1.8 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain HI0933_like PF03486.14 OAG37868.1 - 0.08 11.6 0.0 6.4 5.4 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein NAD_Gly3P_dh_N PF01210.23 OAG37868.1 - 0.081 12.9 0.7 1 9.3 0.3 2.4 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Shikimate_DH PF01488.20 OAG37868.1 - 0.19 11.8 0.0 3.9 7.5 0.0 2.5 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase SGL PF08450.12 OAG37869.1 - 1.2e-08 34.9 0.2 5e-08 32.8 0.2 2.1 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Lactamase_B PF00753.27 OAG37870.1 - 4.3e-11 43.2 0.2 9.3e-11 42.1 0.2 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OAG37870.1 - 0.00015 21.3 0.0 0.00015 21.3 0.0 2.1 3 0 0 3 3 3 1 Beta-lactamase superfamily domain AMP-binding PF00501.28 OAG37871.1 - 7e-75 252.2 0.0 9.3e-75 251.8 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG37871.1 - 1.1e-13 52.0 0.0 2.5e-13 50.8 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Thiolase_N PF00108.23 OAG37872.1 - 4.8e-13 49.1 0.0 1.6e-11 44.1 0.0 2.2 1 1 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 OAG37872.1 - 2.5e-09 36.8 0.3 2.4e-08 33.6 0.1 2.5 2 1 1 3 3 3 1 Thiolase, C-terminal domain ACP_syn_III PF08545.10 OAG37872.1 - 7e-06 25.8 0.0 0.00056 19.7 0.0 2.6 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.26 OAG37872.1 - 0.039 13.5 0.0 0.085 12.4 0.0 1.5 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain adh_short_C2 PF13561.6 OAG37873.1 - 4.3e-38 131.2 1.8 1.8e-24 86.6 0.1 3.0 1 1 2 3 3 3 3 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG37873.1 - 1.2e-35 122.8 1.4 3.2e-27 95.3 0.0 2.1 1 1 1 2 2 2 2 short chain dehydrogenase KR PF08659.10 OAG37873.1 - 6e-11 42.6 0.2 5.4e-08 33.0 0.0 2.1 1 1 1 2 2 2 2 KR domain DAO PF01266.24 OAG37874.1 - 2.2e-58 198.5 0.5 2.6e-58 198.3 0.5 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAG37874.1 - 0.00019 21.6 0.5 0.00053 20.2 0.5 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 OAG37874.1 - 0.0044 16.3 0.0 0.0086 15.3 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 OAG37874.1 - 0.025 13.8 0.4 0.075 12.3 0.2 1.9 3 0 0 3 3 3 0 FAD binding domain FAD_oxidored PF12831.7 OAG37874.1 - 0.033 13.6 0.0 0.047 13.1 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase ApbA PF02558.16 OAG37874.1 - 0.048 13.3 0.2 0.085 12.5 0.2 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.14 OAG37874.1 - 0.049 12.8 0.6 0.091 12.0 0.2 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG37874.1 - 0.052 12.8 0.3 0.073 12.3 0.3 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAG37874.1 - 0.055 14.0 0.2 0.15 12.6 0.2 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAG37874.1 - 0.072 11.8 0.4 0.1 11.3 0.4 1.1 1 0 0 1 1 1 0 HI0933-like protein TrkA_N PF02254.18 OAG37874.1 - 0.14 12.4 0.1 0.25 11.6 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_9 PF13454.6 OAG37874.1 - 0.14 12.1 0.2 0.23 11.4 0.2 1.3 1 0 0 1 1 1 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 OAG37874.1 - 0.22 10.6 0.4 0.35 9.8 0.4 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_2 PF00890.24 OAG37874.1 - 0.3 10.1 1.8 0.56 9.2 1.8 1.3 1 0 0 1 1 1 0 FAD binding domain FAD_binding_3 PF01494.19 OAG37875.1 - 3.3e-26 92.4 0.0 5.7e-09 35.7 0.0 3.0 3 0 0 3 3 3 3 FAD binding domain Pyr_redox PF00070.27 OAG37875.1 - 3.1e-06 27.6 0.2 0.0044 17.6 0.0 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG37875.1 - 6.8e-06 26.2 0.0 1.8e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAG37875.1 - 3.6e-05 23.1 0.0 0.0094 15.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAG37875.1 - 5.4e-05 22.9 0.0 0.0013 18.4 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 OAG37875.1 - 0.0045 16.1 0.0 0.021 13.9 0.0 2.0 3 0 0 3 3 3 1 Lycopene cyclase protein Amino_oxidase PF01593.24 OAG37875.1 - 0.0053 16.1 0.7 1.3 8.2 0.0 2.5 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase IlvN PF07991.12 OAG37875.1 - 0.0053 16.3 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain HI0933_like PF03486.14 OAG37875.1 - 0.0057 15.4 0.0 0.0098 14.6 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 OAG37875.1 - 0.012 14.7 0.0 0.019 14.1 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 OAG37875.1 - 0.016 14.5 0.0 0.051 12.8 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 OAG37875.1 - 0.023 14.3 0.0 0.053 13.2 0.0 1.6 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.23 OAG37875.1 - 0.028 14.4 0.0 0.049 13.6 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Shikimate_DH PF01488.20 OAG37875.1 - 0.039 14.0 0.0 0.067 13.2 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Glu_dehyd_C PF16912.5 OAG37875.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus PALP PF00291.25 OAG37875.1 - 0.2 11.0 0.0 0.32 10.3 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme Methyltransf_23 PF13489.6 OAG37876.1 - 3.8e-31 108.2 0.0 5.4e-31 107.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG37876.1 - 1.9e-14 54.1 0.0 3.9e-14 53.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG37876.1 - 1.3e-12 47.7 0.0 6.9e-12 45.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG37876.1 - 2.5e-11 44.1 0.0 5e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG37876.1 - 9.9e-11 42.3 0.0 6.2e-10 39.7 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain FtsJ PF01728.19 OAG37876.1 - 7.8e-05 22.9 0.0 0.00012 22.2 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Ubie_methyltran PF01209.18 OAG37876.1 - 0.00014 21.3 0.0 0.00056 19.3 0.0 1.9 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 OAG37876.1 - 0.00017 21.2 0.0 0.00027 20.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Met_10 PF02475.16 OAG37876.1 - 0.00059 19.6 0.0 0.00085 19.1 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_4 PF02390.17 OAG37876.1 - 0.00061 19.3 0.0 0.0038 16.7 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_16 PF10294.9 OAG37876.1 - 0.00088 19.0 0.0 0.0016 18.2 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_2 PF00891.18 OAG37876.1 - 0.0094 15.3 0.0 0.03 13.6 0.0 1.9 2 1 0 2 2 2 1 O-methyltransferase domain Cons_hypoth95 PF03602.15 OAG37876.1 - 0.032 13.9 0.0 0.051 13.2 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 DUF938 PF06080.12 OAG37876.1 - 0.05 13.4 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF938) PrmA PF06325.13 OAG37876.1 - 0.14 11.6 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) CheR PF01739.18 OAG37876.1 - 0.15 11.5 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain LRR_6 PF13516.6 OAG37877.1 - 0.023 14.7 5.6 25 5.3 0.1 5.7 6 0 0 6 6 6 0 Leucine Rich repeat Gly_transf_sug PF04488.15 OAG37878.1 - 3.2e-21 75.8 0.0 5.8e-21 75.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 OAG37878.1 - 1 8.6 2.4 1 8.6 0.3 1.8 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain SKG6 PF08693.10 OAG37879.1 - 0.0041 16.5 0.9 0.0093 15.4 0.9 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Mid2 PF04478.12 OAG37879.1 - 0.033 14.0 0.0 0.098 12.5 0.0 1.8 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor FerA PF08165.11 OAG37879.1 - 0.18 11.7 0.0 0.35 10.8 0.0 1.4 1 0 0 1 1 1 0 FerA (NUC095) domain Abhydrolase_1 PF00561.20 OAG37882.1 - 2.5e-12 47.0 0.5 6.5e-11 42.4 0.1 2.6 2 1 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAG37882.1 - 2.4e-09 36.8 0.0 7.6e-09 35.2 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Cohesin_load PF10345.9 OAG37883.1 - 1.7e-100 337.2 1.0 2.1e-100 336.9 1.0 1.0 1 0 0 1 1 1 1 Cohesin loading factor TPR_12 PF13424.6 OAG37883.1 - 0.0003 21.0 6.4 0.062 13.6 0.5 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 OAG37883.1 - 0.0075 17.0 6.1 1.3 10.0 0.1 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 OAG37883.1 - 0.035 14.3 0.8 0.35 11.2 0.3 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 OAG37883.1 - 0.038 14.6 5.6 0.59 10.8 0.1 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 OAG37883.1 - 0.04 14.5 3.3 12 6.9 0.3 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 OAG37883.1 - 0.069 13.0 0.4 0.069 13.0 0.4 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 OAG37883.1 - 0.09 12.6 1.0 7.4 6.6 0.3 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 OAG37883.1 - 0.49 11.2 2.2 56 4.7 0.3 3.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 OAG37883.1 - 3 8.2 16.3 0.73 10.1 0.3 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat NIF PF03031.18 OAG37884.1 - 9.1e-19 67.8 0.0 1.5e-18 67.1 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase RRP36 PF06102.12 OAG37885.1 - 2.9e-38 131.4 26.9 2.9e-38 131.4 26.9 2.0 2 1 0 2 2 2 1 rRNA biogenesis protein RRP36 ADH_N PF08240.12 OAG37886.1 - 4.9e-18 65.0 3.1 9.1e-18 64.1 3.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG37886.1 - 7.1e-13 48.7 0.2 1.8e-12 47.4 0.2 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Amdase PF17645.1 OAG37886.1 - 0.018 14.7 0.0 2.6 7.6 0.0 2.3 2 0 0 2 2 2 0 Arylmalonate decarboxylase adh_short PF00106.25 OAG37886.1 - 0.032 13.7 0.3 0.072 12.5 0.3 1.6 1 0 0 1 1 1 0 short chain dehydrogenase Methyltransf_25 PF13649.6 OAG37886.1 - 0.054 14.2 0.6 4.5 8.1 0.1 2.8 1 1 1 2 2 2 0 Methyltransferase domain RNA_pol_L_2 PF13656.6 OAG37888.1 - 2.4e-29 100.9 0.0 3.5e-29 100.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 OAG37888.1 - 5.4e-10 38.6 0.0 1.2e-09 37.4 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb3/Rpb11 dimerisation domain AdoMet_dc PF02675.15 OAG37888.1 - 0.0051 17.0 0.0 0.0086 16.3 0.0 1.4 1 1 0 1 1 1 1 S-adenosylmethionine decarboxylase DUF4726 PF15855.5 OAG37888.1 - 0.21 11.8 0.0 0.29 11.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4726) IGPD PF00475.18 OAG37889.1 - 2.7e-56 189.9 0.2 3.1e-55 186.5 0.4 1.9 2 0 0 2 2 2 1 Imidazoleglycerol-phosphate dehydratase Arena_RNA_pol PF06317.11 OAG37889.1 - 0.072 10.3 0.0 0.095 9.9 0.0 1.0 1 0 0 1 1 1 0 Arenavirus RNA polymerase DER1 PF04511.15 OAG37890.1 - 7.8e-52 176.0 3.8 9e-52 175.8 3.8 1.0 1 0 0 1 1 1 1 Der1-like family EF1G PF00647.19 OAG37891.1 - 1.3e-47 160.3 0.0 2.5e-47 159.4 0.0 1.5 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_N PF02798.20 OAG37891.1 - 6.5e-11 42.4 1.0 2.7e-10 40.5 0.0 2.5 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OAG37891.1 - 1e-10 41.7 0.0 1e-10 41.7 0.0 2.2 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 OAG37891.1 - 2.3e-07 31.1 0.2 3e-06 27.5 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAG37891.1 - 1.2e-05 25.2 0.0 3.5e-05 23.7 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 OAG37891.1 - 9.9e-05 22.6 0.1 0.00073 19.8 0.0 2.4 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 OAG37891.1 - 0.0012 18.9 0.0 0.0034 17.5 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Ribosomal_S9 PF00380.19 OAG37892.1 - 2e-40 138.1 0.1 3.1e-40 137.4 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Pyr_redox_2 PF07992.14 OAG37894.1 - 1.7e-11 43.9 0.0 5.7e-10 38.9 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 OAG37894.1 - 2.7e-10 39.3 0.0 1.3e-09 37.0 0.0 1.9 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OAG37894.1 - 1.7e-09 37.4 0.0 5.2e-09 35.8 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG37894.1 - 1.5e-06 28.3 0.0 3.4e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 OAG37894.1 - 3.1e-06 27.2 0.1 0.00044 20.3 0.1 2.5 1 1 0 1 1 1 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 OAG37894.1 - 7.6e-06 25.3 0.0 2e-05 23.9 0.0 1.6 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 OAG37894.1 - 0.0067 16.1 7.2 0.12 11.9 0.1 3.0 1 1 1 2 2 2 2 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 OAG37894.1 - 0.0079 15.5 0.1 0.014 14.7 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 OAG37894.1 - 0.013 14.2 0.1 0.74 8.4 0.1 2.2 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.17 OAG37894.1 - 0.024 13.9 0.0 0.51 9.5 0.0 2.1 2 0 0 2 2 2 0 Thi4 family Pyr_redox PF00070.27 OAG37894.1 - 0.032 14.8 0.2 13 6.4 0.0 2.7 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OAG37894.1 - 0.12 11.4 0.0 0.7 8.9 0.0 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_2 PF00890.24 OAG37894.1 - 0.14 11.2 1.2 0.25 10.4 1.2 1.3 1 0 0 1 1 1 0 FAD binding domain Erf4 PF10256.9 OAG37895.1 - 4.4e-38 129.9 0.0 6.2e-38 129.5 0.0 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family CFEM PF05730.11 OAG37896.1 - 1.4e-06 28.3 10.1 3.1e-06 27.2 10.1 1.6 1 0 0 1 1 1 1 CFEM domain DNA_pol3_delta2 PF13177.6 OAG37897.1 - 2.4e-13 50.2 0.0 7.3e-10 38.9 0.0 2.2 1 1 1 2 2 2 2 DNA polymerase III, delta subunit Rep_fac_C PF08542.11 OAG37897.1 - 4.5e-12 46.2 0.3 3e-10 40.4 0.1 2.8 2 1 0 2 2 1 1 Replication factor C C-terminal domain AAA PF00004.29 OAG37897.1 - 4.8e-11 43.2 0.0 7.9e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 OAG37897.1 - 2.4e-07 30.8 0.0 4.2e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OAG37897.1 - 6.1e-06 26.7 0.0 0.00027 21.4 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 OAG37897.1 - 2.8e-05 23.9 0.0 6.4e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_3 PF07726.11 OAG37897.1 - 3.7e-05 23.6 0.0 7.2e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 OAG37897.1 - 6e-05 22.9 0.0 9.4e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 OAG37897.1 - 0.00018 21.8 0.0 0.34 11.2 0.1 2.4 1 1 1 2 2 2 2 AAA domain DNA_pol3_delta PF06144.13 OAG37897.1 - 0.0024 17.7 0.0 0.004 16.9 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Mg_chelatase PF01078.21 OAG37897.1 - 0.0043 16.5 0.0 0.029 13.7 0.0 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI MeaB PF03308.16 OAG37897.1 - 0.0044 16.0 0.0 0.0081 15.2 0.0 1.5 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Rad17 PF03215.15 OAG37897.1 - 0.005 16.8 0.0 0.009 16.0 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_assoc_2 PF16193.5 OAG37897.1 - 0.0058 16.9 0.1 0.029 14.7 0.0 2.2 2 0 0 2 2 2 1 AAA C-terminal domain NTPase_1 PF03266.15 OAG37897.1 - 0.022 14.7 0.0 0.063 13.2 0.0 1.8 1 0 0 1 1 1 0 NTPase AAA_19 PF13245.6 OAG37897.1 - 0.026 14.9 0.3 0.1 12.9 0.2 2.1 2 1 0 2 2 1 0 AAA domain KTI12 PF08433.10 OAG37897.1 - 0.031 13.7 0.0 0.058 12.8 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_11 PF13086.6 OAG37897.1 - 0.042 13.6 0.0 0.064 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 OAG37897.1 - 0.045 13.5 0.0 0.079 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 OAG37897.1 - 0.089 12.4 0.1 0.66 9.5 0.1 2.4 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 OAG37897.1 - 0.096 12.1 0.0 4.6 6.6 0.0 2.4 2 0 0 2 2 2 0 Bacterial TniB protein NmrA PF05368.13 OAG37898.1 - 9.7e-19 67.8 0.0 1.4e-18 67.3 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG37898.1 - 2.3e-17 63.5 0.0 4e-17 62.7 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAG37898.1 - 0.0013 18.3 0.0 0.003 17.1 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OAG37898.1 - 0.0077 15.3 0.0 0.05 12.6 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.17 OAG37898.1 - 0.095 13.3 0.0 0.22 12.1 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.18 OAG37898.1 - 0.11 12.7 0.0 0.58 10.4 0.0 2.2 2 0 0 2 2 2 0 TrkA-N domain NAD_binding_4 PF07993.12 OAG37898.1 - 0.18 10.9 0.1 0.33 10.1 0.1 1.4 1 0 0 1 1 1 0 Male sterility protein DUF4464 PF14713.6 OAG37900.1 - 0.046 13.3 0.5 0.059 12.9 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4464) MFS_3 PF05977.13 OAG37901.1 - 0.021 13.3 2.0 0.024 13.0 2.0 1.1 1 0 0 1 1 1 0 Transmembrane secretion effector NUDIX PF00293.28 OAG37902.1 - 6.6e-07 29.4 0.0 1.6e-06 28.2 0.0 1.7 1 1 0 1 1 1 1 NUDIX domain tRNA-synt_1e PF01406.19 OAG37903.1 - 3.4e-111 371.4 0.3 4.9e-111 370.9 0.3 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 OAG37903.1 - 0.00011 21.1 0.6 0.14 10.9 0.2 2.6 2 0 0 2 2 2 2 tRNA synthetases class I (M) DALR_2 PF09190.11 OAG37903.1 - 0.02 15.4 0.1 0.02 15.4 0.1 2.1 2 0 0 2 2 2 0 DALR domain tRNA-synt_1f PF01921.18 OAG37903.1 - 0.035 13.0 1.5 0.48 9.3 0.3 2.6 3 1 0 3 3 3 0 tRNA synthetases class I (K) Arylsulfotran_2 PF14269.6 OAG37904.1 - 1.1e-54 185.8 0.6 2.2e-54 184.9 0.6 1.5 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 OAG37904.1 - 3.9e-18 65.5 0.0 1.2e-17 63.9 0.0 1.6 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Phage_holin_3_6 PF07332.11 OAG37904.1 - 0.14 12.2 1.9 4.9 7.2 0.1 2.2 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III RTA1 PF04479.13 OAG37905.1 - 3.3e-55 186.9 12.0 3.3e-55 186.9 12.0 1.6 1 1 1 2 2 2 1 RTA1 like protein GCD14 PF08704.10 OAG37906.1 - 1.4e-61 208.4 0.1 9.1e-37 127.1 0.2 2.7 2 0 0 2 2 2 2 tRNA methyltransferase complex GCD14 subunit Abhydrolase_1 PF00561.20 OAG37907.1 - 9.8e-19 68.0 0.0 5.9e-17 62.2 0.0 3.1 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 OAG37907.1 - 5.9e-17 61.7 0.0 1.1e-16 60.8 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein IMS PF00817.20 OAG37908.1 - 7.4e-39 133.1 0.0 1.2e-38 132.5 0.0 1.3 1 0 0 1 1 1 1 impB/mucB/samB family zf_UBZ PF18439.1 OAG37908.1 - 9e-15 54.0 1.6 1.7e-14 53.1 1.6 1.5 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger IMS_C PF11799.8 OAG37908.1 - 6.2e-12 46.2 0.0 1.3e-11 45.2 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 OAG37908.1 - 0.019 15.3 0.0 0.041 14.2 0.0 1.5 1 0 0 1 1 1 0 IMS family HHH motif DUF3862 PF12978.7 OAG37908.1 - 0.05 13.4 0.0 0.13 12.0 0.0 1.6 2 0 0 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3862) Chromo_shadow PF01393.19 OAG37908.1 - 0.069 13.3 0.1 0.15 12.2 0.1 1.5 1 0 0 1 1 1 0 Chromo shadow domain DUF2197 PF09963.9 OAG37908.1 - 0.093 13.0 0.0 0.24 11.7 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2197) zf-B_box PF00643.24 OAG37908.1 - 0.14 12.3 0.5 0.28 11.4 0.5 1.4 1 0 0 1 1 1 0 B-box zinc finger Acyl-CoA_dh_1 PF00441.24 OAG37909.1 - 6.9e-43 146.4 0.4 1.1e-42 145.8 0.4 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 OAG37909.1 - 4.6e-31 107.8 0.0 9.4e-31 106.8 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 OAG37909.1 - 1.6e-27 95.5 0.2 3.2e-27 94.6 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 OAG37909.1 - 2.1e-14 53.9 0.0 4.2e-14 53.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 OAG37909.1 - 2.9e-05 23.9 0.3 0.00013 21.7 0.3 2.0 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Oxidored_FMN PF00724.20 OAG37909.1 - 0.17 11.2 0.2 0.26 10.5 0.2 1.2 1 0 0 1 1 1 0 NADH:flavin oxidoreductase / NADH oxidase family HAD PF12710.7 OAG37910.1 - 8.8e-24 84.9 0.0 1.3e-23 84.4 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 OAG37910.1 - 0.00063 19.2 0.0 0.0018 17.7 0.0 1.6 1 1 0 1 1 1 1 Putative Phosphatase UMPH-1 PF05822.12 OAG37910.1 - 0.00088 18.9 0.0 0.0016 18.0 0.0 1.5 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) Hydrolase PF00702.26 OAG37910.1 - 0.018 15.3 0.2 0.071 13.4 0.1 2.0 1 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase TPR_11 PF13414.6 OAG37910.1 - 0.1 12.3 0.0 19 5.1 0.0 2.3 2 0 0 2 2 2 0 TPR repeat TYW3 PF02676.14 OAG37911.1 - 1.1e-62 211.1 0.0 2.2e-62 210.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase TYW3 Methyltransf_23 PF13489.6 OAG37912.1 - 1.8e-12 47.4 0.0 3.5e-12 46.5 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG37912.1 - 8.8e-10 39.2 0.0 2.3e-06 28.2 0.0 2.7 1 1 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 OAG37912.1 - 1.3e-09 38.5 0.1 8.4e-08 32.8 0.1 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG37912.1 - 2e-09 37.4 0.0 1.1e-05 25.2 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 OAG37912.1 - 3e-09 37.5 0.0 1.6e-08 35.1 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAG37912.1 - 8.1e-08 31.9 0.0 0.0056 16.0 0.0 2.2 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family RrnaAD PF00398.20 OAG37912.1 - 0.0033 16.5 0.0 0.016 14.3 0.0 1.8 1 1 1 2 2 2 1 Ribosomal RNA adenine dimethylase Pox_MCEL PF03291.16 OAG37912.1 - 0.0035 16.5 0.0 0.0049 16.0 0.0 1.3 1 0 0 1 1 1 1 mRNA capping enzyme TPMT PF05724.11 OAG37912.1 - 0.01 15.5 0.0 0.022 14.4 0.0 1.6 2 0 0 2 2 2 0 Thiopurine S-methyltransferase (TPMT) Ntox25 PF15530.6 OAG37912.1 - 0.12 12.5 0.0 0.19 11.9 0.0 1.2 1 0 0 1 1 1 0 Bacterial toxin 25 DUF2461 PF09365.10 OAG37913.1 - 8.3e-79 264.4 0.0 1.3e-78 263.8 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein (DUF2461) CDC45 PF02724.14 OAG37913.1 - 0.15 10.3 7.5 0.19 9.9 7.5 1.2 1 0 0 1 1 1 0 CDC45-like protein SURF2 PF05477.11 OAG37913.1 - 0.4 10.3 11.0 0.73 9.5 11.0 1.4 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) DUF5427 PF10310.9 OAG37913.1 - 0.65 8.9 13.9 1.1 8.1 13.9 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Presenilin PF01080.17 OAG37913.1 - 3.2 6.4 8.9 4.7 5.9 8.9 1.1 1 0 0 1 1 1 0 Presenilin DNA_pol_phi PF04931.13 OAG37913.1 - 4.4 5.3 11.3 7.1 4.6 11.3 1.3 1 0 0 1 1 1 0 DNA polymerase phi Zn_clus PF00172.18 OAG37914.1 - 7.4e-08 32.4 7.6 1.1e-07 31.9 7.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SOG2 PF10428.9 OAG37914.1 - 2.5 7.2 16.9 4.1 6.5 16.9 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein ARPC4 PF05856.12 OAG37916.1 - 4.7e-78 260.5 3.9 5.6e-78 260.3 3.9 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) UCH PF00443.29 OAG37917.1 - 9.1e-50 169.5 0.0 1.2e-49 169.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OAG37917.1 - 1.2e-11 44.8 5.9 6.3e-09 35.9 5.9 2.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 OAG37917.1 - 3.1e-08 33.3 0.1 8.8e-08 31.8 0.1 1.8 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S30 PF04758.14 OAG37918.1 - 4.1e-26 90.9 10.7 6.9e-26 90.2 10.7 1.4 1 0 0 1 1 1 1 Ribosomal protein S30 4HBT PF03061.22 OAG37918.1 - 0.041 14.2 0.0 7.3 7.0 0.0 2.7 2 0 0 2 2 2 0 Thioesterase superfamily CPP1-like PF11833.8 OAG37918.1 - 0.36 10.5 0.9 0.6 9.7 0.0 1.7 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like TRI12 PF06609.13 OAG37919.1 - 7.8e-33 113.8 28.7 1e-32 113.4 28.7 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG37919.1 - 1.3e-21 77.0 50.0 1.3e-21 77.0 50.0 1.7 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG37919.1 - 5.3e-11 42.0 38.1 9.7e-11 41.2 16.1 3.0 2 1 0 2 2 2 2 Sugar (and other) transporter SET PF00856.28 OAG37920.1 - 5.6e-17 62.6 0.0 1.4e-15 58.1 0.0 2.1 1 1 0 1 1 1 1 SET domain SAF PF08666.12 OAG37920.1 - 0.0038 17.8 0.0 0.69 10.6 0.0 2.3 2 0 0 2 2 2 2 SAF domain Glu_cyclase_2 PF05096.12 OAG37920.1 - 0.037 13.5 0.0 0.061 12.8 0.0 1.3 1 0 0 1 1 1 0 Glutamine cyclotransferase DUF3918 PF13056.6 OAG37920.1 - 0.18 11.5 0.2 0.31 10.7 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3918) Pyr_redox_2 PF07992.14 OAG37921.1 - 1.2e-28 100.2 0.0 1.7e-28 99.7 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAG37921.1 - 1.1e-09 38.7 0.7 1.6e-07 31.8 0.7 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG37921.1 - 1.9e-08 33.9 0.1 8.3e-08 31.8 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAG37921.1 - 0.0016 18.4 0.1 8.6 6.3 0.0 3.5 3 0 0 3 3 3 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 OAG37921.1 - 0.17 10.9 1.0 6.5 5.7 0.0 2.8 2 1 1 3 3 3 0 Lycopene cyclase protein Trp_halogenase PF04820.14 OAG37921.1 - 0.45 9.3 5.0 3.3 6.4 0.1 2.4 3 0 0 3 3 3 0 Tryptophan halogenase DAO PF01266.24 OAG37921.1 - 0.54 9.8 5.1 13 5.2 0.1 3.4 2 1 2 4 4 4 0 FAD dependent oxidoreductase DUF3597 PF12200.8 OAG37921.1 - 3.1 8.4 4.5 5.8 7.5 4.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3597) Lyase_1 PF00206.20 OAG37922.1 - 2.1e-114 382.2 0.0 3e-114 381.6 0.0 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 OAG37922.1 - 7.8e-21 74.2 0.0 1.9e-20 73.0 0.0 1.7 1 0 0 1 1 1 1 Fumarase C C-terminus Antimicrobial_2 PF08023.12 OAG37922.1 - 0.15 12.6 3.3 1.9 9.1 0.0 3.4 3 0 0 3 3 3 0 Frog antimicrobial peptide Fungal_trans PF04082.18 OAG37923.1 - 8.3e-16 57.8 1.7 2.4e-15 56.3 0.2 2.4 2 1 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 OAG37923.1 - 6.2e-11 42.1 7.7 6.3e-05 23.2 0.2 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OAG37923.1 - 1e-08 35.2 1.8 1e-08 35.2 1.8 3.5 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 OAG37923.1 - 1.2e-08 35.1 7.4 0.0022 18.7 2.1 3.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OAG37923.1 - 1.5e-05 25.1 0.2 0.28 11.5 0.0 2.9 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 OAG37923.1 - 0.00021 21.5 3.5 0.00048 20.4 3.5 1.6 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2HC_2 PF13913.6 OAG37923.1 - 0.0095 15.8 4.1 1.6 8.7 1.3 2.4 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-met PF12874.7 OAG37923.1 - 0.069 13.6 1.0 7.3 7.1 0.1 2.9 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf_C2H2_ZHX PF18387.1 OAG37923.1 - 0.83 9.3 4.0 0.41 10.3 0.4 2.3 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_6 PF13912.6 OAG37923.1 - 0.84 9.7 4.3 0.72 9.9 0.1 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger MelC1 PF06236.11 OAG37925.1 - 0.012 15.7 0.1 2 8.5 0.0 3.5 3 0 0 3 3 3 0 Tyrosinase co-factor MelC1 Exo_endo_phos PF03372.23 OAG37926.1 - 3.5e-06 26.7 0.0 1.1e-05 25.1 0.0 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family FAD_binding_4 PF01565.23 OAG37927.1 - 2.9e-22 78.9 0.9 6.9e-22 77.7 0.9 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 OAG37927.1 - 0.0008 19.5 0.0 0.0019 18.3 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like CitMHS PF03600.16 OAG37928.1 - 0.02 14.1 2.8 0.027 13.7 2.8 1.3 1 0 0 1 1 1 0 Citrate transporter p450 PF00067.22 OAG37929.1 - 2.7e-54 184.6 0.0 3.6e-54 184.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF3196 PF11428.8 OAG37929.1 - 0.17 11.3 0.0 0.29 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3196) WSC PF01822.19 OAG37931.1 - 8.1e-07 29.1 12.9 8.1e-07 29.1 12.9 1.9 2 0 0 2 2 2 1 WSC domain Podoplanin PF05808.11 OAG37931.1 - 0.00027 21.1 6.4 0.00027 21.1 6.4 2.4 1 1 1 2 2 2 1 Podoplanin Rax2 PF12768.7 OAG37931.1 - 0.0029 17.1 0.9 0.0064 16.0 0.9 1.6 1 1 0 1 1 1 1 Cortical protein marker for cell polarity LapA_dom PF06305.11 OAG37931.1 - 0.018 14.8 0.3 0.036 13.9 0.3 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain AMP-binding PF00501.28 OAG37932.1 - 3.4e-81 273.0 0.0 4.4e-81 272.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG37932.1 - 2.6e-14 54.0 0.8 5.6e-14 52.9 0.8 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain 7TM_GPCR_Srv PF10323.9 OAG37932.1 - 0.054 12.9 0.2 0.085 12.2 0.2 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv BTHB PF18410.1 OAG37932.1 - 0.16 11.8 0.0 0.38 10.6 0.0 1.6 1 0 0 1 1 1 0 Basic tilted helix bundle domain RNA_pol_3_Rpc31 PF11705.8 OAG37933.1 - 1.3e-38 133.5 55.8 6.3e-33 114.9 55.8 2.5 1 1 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 TIMELESS_C PF05029.13 OAG37933.1 - 0.11 11.6 30.2 0.17 11.0 30.2 1.2 1 0 0 1 1 1 0 Timeless protein C terminal region TFIIA PF03153.13 OAG37933.1 - 9.2 6.1 24.0 11 5.8 24.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Aminotran_5 PF00266.19 OAG37935.1 - 4.7e-26 91.6 0.0 1.4e-19 70.3 0.0 2.3 1 1 1 2 2 2 2 Aminotransferase class-V RFC1 PF08519.12 OAG37935.1 - 0.077 13.2 0.0 0.54 10.4 0.0 2.1 2 0 0 2 2 2 0 Replication factor RFC1 C terminal domain Abhydrolase_6 PF12697.7 OAG37936.1 - 7.3e-06 26.7 0.5 1.1e-05 26.2 0.5 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 OAG37936.1 - 0.033 13.8 0.2 0.069 12.8 0.1 1.5 2 0 0 2 2 2 0 Putative esterase Ribosomal_L16 PF00252.18 OAG37938.1 - 2.3e-31 108.6 0.0 3.1e-31 108.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Amidase PF01425.21 OAG37939.1 - 3.2e-94 316.4 0.1 3.7e-94 316.2 0.1 1.0 1 0 0 1 1 1 1 Amidase LamB_YcsF PF03746.16 OAG37941.1 - 4.4e-84 281.9 0.0 5e-84 281.7 0.0 1.0 1 0 0 1 1 1 1 LamB/YcsF family HRI1 PF16815.5 OAG37942.1 - 6e-29 101.4 0.6 7.1e-29 101.2 0.6 1.0 1 0 0 1 1 1 1 Protein HRI1 Aa_trans PF01490.18 OAG37943.1 - 3.4e-27 95.2 33.2 4.8e-27 94.7 33.2 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein TetR_C_22 PF17928.1 OAG37944.1 - 0.1 12.9 0.1 0.31 11.4 0.1 1.8 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain DUF3112 PF11309.8 OAG37945.1 - 6.7e-10 38.8 3.7 8.6e-05 22.1 0.1 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF3112) MIG-14_Wnt-bd PF06664.12 OAG37945.1 - 0.0053 16.0 14.8 1.1 8.4 14.8 2.1 1 1 0 1 1 1 1 Wnt-binding factor required for Wnt secretion DUF2157 PF09925.9 OAG37945.1 - 0.97 9.2 7.9 2.2 8.0 0.1 2.9 1 1 2 3 3 3 0 Predicted membrane protein (DUF2157) RFC1 PF08519.12 OAG37946.1 - 2.2e-58 196.9 0.0 1.4e-57 194.2 0.0 2.3 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain BRCT PF00533.26 OAG37946.1 - 9.1e-14 51.6 0.0 2.9e-13 50.0 0.0 2.0 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.29 OAG37946.1 - 1.5e-09 38.4 0.0 3.7e-09 37.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 OAG37946.1 - 1.3e-06 28.5 0.0 3.1e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 OAG37946.1 - 0.00046 20.5 0.0 0.0019 18.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OAG37946.1 - 0.00063 20.2 1.4 0.0029 18.0 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 OAG37946.1 - 0.0035 17.5 1.1 0.0069 16.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 OAG37946.1 - 0.0045 16.7 0.1 0.014 15.2 0.1 1.8 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 OAG37946.1 - 0.0047 16.7 0.0 0.0097 15.7 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 OAG37946.1 - 0.012 16.2 0.2 0.012 16.2 0.2 2.4 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 OAG37946.1 - 0.02 14.8 0.0 2.9 7.8 0.0 2.7 3 0 0 3 3 3 0 NACHT domain PTCB-BRCT PF12738.7 OAG37946.1 - 0.026 14.5 0.0 0.06 13.3 0.0 1.7 1 0 0 1 1 1 0 twin BRCT domain AAA_14 PF13173.6 OAG37946.1 - 0.06 13.4 0.0 0.18 11.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 OAG37946.1 - 0.074 13.0 0.0 0.24 11.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 OAG37946.1 - 0.73 10.1 4.8 0.36 11.1 0.1 2.6 2 0 0 2 2 2 0 AAA domain Arrestin_N PF00339.29 OAG37947.1 - 7.3e-10 39.1 0.0 2e-09 37.7 0.0 1.7 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain DUF3449 PF11931.8 OAG37948.1 - 2.5e-72 242.5 0.0 7.4e-72 241.0 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) SF3A3 PF16837.5 OAG37948.1 - 1.5e-26 92.7 1.6 2.6e-26 92.0 0.3 2.1 3 0 0 3 3 3 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 SF3a60_bindingd PF12108.8 OAG37948.1 - 9e-15 54.3 0.4 1.8e-14 53.3 0.4 1.5 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-met PF12874.7 OAG37948.1 - 7.7e-09 35.7 2.8 2.4e-07 30.9 0.5 2.3 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 OAG37948.1 - 1.1e-06 28.8 0.6 1.1e-06 28.8 0.6 2.7 2 1 0 2 2 2 1 Zinc-finger double-stranded RNA-binding PRP9_N PF16958.5 OAG37948.1 - 9.4e-05 22.5 7.8 0.049 13.7 0.4 3.1 2 1 1 3 3 3 2 Pre-mRNA-splicing factor PRP9 N-terminus zf-C2H2_2 PF12756.7 OAG37948.1 - 0.00056 20.2 0.2 0.017 15.5 0.1 2.4 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 OAG37948.1 - 0.031 15.1 1.6 1.4 9.9 0.1 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 OAG37948.1 - 0.34 11.5 4.8 0.32 11.5 0.6 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type Cnd3 PF12719.7 OAG37949.1 - 9.4e-44 149.8 4.3 5.1e-43 147.3 0.2 3.3 3 1 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 OAG37949.1 - 3.6e-09 36.9 12.8 6.1e-05 23.3 4.8 5.2 3 1 1 5 5 5 2 HEAT repeats HEAT PF02985.22 OAG37949.1 - 2.4e-06 27.3 15.7 0.04 14.2 0.0 7.3 7 0 0 7 7 7 3 HEAT repeat Cnd1 PF12717.7 OAG37949.1 - 0.00068 19.7 1.0 0.11 12.5 0.4 3.9 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 OAG37949.1 - 0.0027 18.2 12.8 0.012 16.1 0.5 5.4 6 0 0 6 6 6 1 HEAT-like repeat APH PF01636.23 OAG37950.1 - 0.14 12.0 0.2 7.3 6.4 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family zf-BED PF02892.15 OAG37950.1 - 0.64 10.1 3.9 2.6 8.1 0.2 2.6 2 0 0 2 2 2 0 BED zinc finger PqqA PF08042.11 OAG37951.1 - 0.43 10.7 4.8 14 5.9 0.2 3.1 3 0 0 3 3 3 0 PqqA family Sugar_tr PF00083.24 OAG37952.1 - 3.3e-79 266.9 22.9 3.8e-79 266.7 22.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG37952.1 - 9.6e-32 110.3 46.8 6.6e-29 100.9 26.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 OAG37952.1 - 2.5e-09 36.2 10.8 1e-05 24.2 3.7 2.2 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 OAG37952.1 - 0.001 17.5 1.8 0.0019 16.5 1.8 1.5 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family PUCC PF03209.15 OAG37952.1 - 0.0015 17.6 11.2 0.0015 17.6 11.2 2.1 2 0 0 2 2 2 1 PUCC protein AP_endonuc_2 PF01261.24 OAG37953.1 - 1.2e-25 90.3 0.1 1.5e-25 89.9 0.1 1.1 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Fungal_trans PF04082.18 OAG37954.1 - 2.3e-29 102.3 0.3 3.2e-29 101.8 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short_C2 PF13561.6 OAG37955.1 - 1.5e-48 165.4 0.5 7.1e-47 159.9 0.5 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG37955.1 - 3.2e-34 118.1 2.3 2.4e-33 115.3 2.3 1.9 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG37955.1 - 1.3e-07 31.7 0.0 2.5e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 OAG37955.1 - 0.00089 18.3 0.1 0.0017 17.4 0.1 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 OAG37955.1 - 0.029 13.8 0.1 0.12 11.9 0.1 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.26 OAG37955.1 - 0.031 14.3 0.0 0.062 13.3 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Pkinase PF00069.25 OAG37956.1 - 6.7e-53 179.7 0.0 9.3e-53 179.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG37956.1 - 7.8e-19 68.0 0.3 1.4e-18 67.1 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 OAG37956.1 - 0.08 12.9 0.1 0.08 12.9 0.1 2.1 2 1 1 3 3 3 0 Phosphotransferase enzyme family RIO1 PF01163.22 OAG37956.1 - 0.16 11.6 0.1 0.31 10.6 0.1 1.4 1 0 0 1 1 1 0 RIO1 family Pex24p PF06398.11 OAG37957.1 - 8.8e-84 281.6 0.0 1.1e-83 281.2 0.0 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin PRT_C PF08372.10 OAG37957.1 - 0.1 12.3 0.6 0.28 10.9 0.6 1.7 1 0 0 1 1 1 0 Plant phosphoribosyltransferase C-terminal DUF3292 PF11696.8 OAG37957.1 - 1.1 7.6 13.0 0.12 10.7 0.8 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3292) STE2 PF02116.15 OAG37958.1 - 2.4e-17 63.2 19.5 3.4e-17 62.7 19.5 1.1 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR DUF5134 PF17197.4 OAG37958.1 - 0.12 12.2 2.7 0.44 10.4 2.7 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF5134) DUF1996 PF09362.10 OAG37960.1 - 1.3e-88 297.0 1.3 1.8e-88 296.5 1.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) WSC PF01822.19 OAG37960.1 - 9.4e-19 67.4 9.5 3.1e-18 65.7 9.5 2.0 1 0 0 1 1 1 1 WSC domain Band_7 PF01145.25 OAG37961.1 - 5e-25 88.5 10.3 5.8e-25 88.3 9.0 1.7 1 1 1 2 2 2 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 OAG37961.1 - 0.0046 16.1 5.2 0.0066 15.6 5.2 1.3 1 0 0 1 1 1 1 SigmaW regulon antibacterial DUF1754 PF08555.10 OAG37962.1 - 7.9e-12 45.8 20.4 7.9e-12 45.8 20.4 3.2 3 1 0 3 3 3 1 Eukaryotic family of unknown function (DUF1754) BCDHK_Adom3 PF10436.9 OAG37963.1 - 1.3e-74 249.4 0.0 1.9e-74 248.9 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 OAG37963.1 - 3.7e-09 37.1 0.0 6.9e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 OAG37963.1 - 0.05 13.4 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Lipase_GDSL PF00657.22 OAG37964.1 - 0.0082 16.1 0.0 0.047 13.7 0.0 2.0 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DUF5605 PF18310.1 OAG37964.1 - 0.18 11.7 0.7 1.2 9.1 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5605) LSM PF01423.22 OAG37965.1 - 2.7e-13 49.4 0.0 4.8e-13 48.6 0.0 1.4 1 1 0 1 1 1 1 LSM domain adh_short PF00106.25 OAG37966.1 - 2.8e-18 66.1 1.4 2.6e-15 56.4 0.6 2.4 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAG37966.1 - 8.2e-10 38.6 0.8 1e-07 31.8 0.5 2.3 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG37966.1 - 1.1e-09 38.4 0.4 2.2e-09 37.5 0.2 1.6 2 0 0 2 2 2 1 KR domain NAD_binding_4 PF07993.12 OAG37966.1 - 0.014 14.6 0.0 0.13 11.4 0.0 2.2 1 1 0 1 1 1 0 Male sterility protein Polysacc_synt_2 PF02719.15 OAG37966.1 - 0.024 13.8 0.0 0.043 12.9 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein zf-BED PF02892.15 OAG37967.1 - 0.11 12.5 0.1 0.24 11.4 0.1 1.5 1 0 0 1 1 1 0 BED zinc finger His_Phos_1 PF00300.22 OAG37968.1 - 4.2e-27 95.1 0.4 6.4e-27 94.5 0.4 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) SAM_2 PF07647.17 OAG37969.1 - 1.7e-08 34.4 0.1 2e-06 27.8 0.1 2.4 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 OAG37969.1 - 0.00023 21.6 0.1 0.00055 20.3 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF4508 PF14969.6 OAG37969.1 - 0.15 12.3 1.6 2.1 8.6 1.6 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4508) Rab5ip PF07019.12 OAG37970.1 - 3.5e-23 82.0 3.9 4.4e-23 81.7 3.9 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) HSP70 PF00012.20 OAG37972.1 - 1.7e-269 895.1 16.5 1.9e-269 894.9 16.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 OAG37972.1 - 7.1e-14 51.4 10.5 1.3e-12 47.2 3.9 2.9 3 0 0 3 3 3 2 MreB/Mbl protein FGGY_C PF02782.16 OAG37972.1 - 0.00014 21.6 0.1 0.00036 20.3 0.1 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DUF4363 PF14276.6 OAG37972.1 - 0.048 13.8 5.3 0.098 12.8 5.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4363) Med9 PF07544.13 OAG37972.1 - 0.43 10.7 6.5 0.55 10.4 1.1 3.1 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 RRN3 PF05327.11 OAG37972.1 - 0.57 8.7 6.1 0.89 8.0 6.1 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 FtsA PF14450.6 OAG37972.1 - 0.98 9.9 10.9 2.4 8.7 0.4 4.1 3 3 0 3 3 3 0 Cell division protein FtsA TBCC_N PF16752.5 OAG37972.1 - 2.9 8.4 9.6 0.36 11.3 4.8 1.9 2 0 0 2 2 2 0 Tubulin-specific chaperone C N-terminal domain DUF2415 PF10313.9 OAG37973.1 - 2.8e-13 49.5 0.1 1.7e-12 47.0 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised protein domain (DUF2415) WD40 PF00400.32 OAG37973.1 - 4.3e-06 27.4 0.3 12 7.0 0.1 5.6 5 0 0 5 5 5 3 WD domain, G-beta repeat Ge1_WD40 PF16529.5 OAG37973.1 - 0.07 12.1 0.0 0.69 8.8 0.0 2.4 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Ribosomal_L21p PF00829.21 OAG37974.1 - 3.8e-05 23.9 0.0 6.9e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein HET PF06985.11 OAG37975.1 - 2.4e-24 86.3 0.0 4.8e-24 85.4 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) NmrA PF05368.13 OAG37976.1 - 1.3e-13 51.0 0.0 2e-13 50.5 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG37976.1 - 9.8e-13 48.4 0.0 1.5e-12 47.8 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAG37976.1 - 0.0018 17.8 0.1 0.033 13.6 0.0 2.3 1 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OAG37976.1 - 0.0033 16.5 0.0 0.0052 15.8 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.18 OAG37976.1 - 0.0062 16.8 0.0 0.019 15.2 0.0 1.8 2 1 0 2 2 2 1 TrkA-N domain F420_oxidored PF03807.17 OAG37976.1 - 0.0084 16.7 0.0 0.015 15.8 0.0 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent PNP_UDP_1 PF01048.20 OAG37976.1 - 0.15 11.3 0.0 0.25 10.5 0.0 1.3 1 0 0 1 1 1 0 Phosphorylase superfamily NUC173 PF08161.12 OAG37977.1 - 2.7e-72 242.7 0.0 1e-70 237.6 0.0 3.1 2 0 0 2 2 2 1 NUC173 domain HEAT PF02985.22 OAG37977.1 - 0.00023 21.1 0.6 0.35 11.2 0.0 4.2 3 0 0 3 3 3 1 HEAT repeat CLASP_N PF12348.8 OAG37977.1 - 0.012 15.1 0.0 4.1 6.9 0.0 3.9 4 0 0 4 4 4 0 CLASP N terminal Nipped-B_C PF12830.7 OAG37977.1 - 0.037 14.0 0.4 0.15 11.9 0.0 2.3 2 0 0 2 2 2 0 Sister chromatid cohesion C-terminus SKN1 PF03935.15 OAG37979.1 - 1.5e-211 703.2 7.2 2.6e-209 695.8 7.2 2.0 1 1 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) DUF2833 PF11090.8 OAG37979.1 - 0.18 12.2 0.2 0.49 10.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2833) NuiA PF07924.11 OAG37980.1 - 0.00038 20.9 1.7 0.36 11.2 0.0 2.2 1 1 0 2 2 2 2 Nuclease A inhibitor-like protein DUF5066 PF16728.5 OAG37980.1 - 0.2 11.0 0.0 0.29 10.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5066) Ribosomal_L3 PF00297.22 OAG37981.1 - 6.6e-161 535.4 9.8 7.5e-161 535.2 9.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 TPR_1 PF00515.28 OAG37982.1 - 1.8e-48 160.5 36.7 5.4e-08 32.3 0.1 11.2 12 1 0 12 12 12 9 Tetratricopeptide repeat TPR_2 PF07719.17 OAG37982.1 - 1.6e-45 149.6 23.8 4.2e-06 26.4 0.0 10.6 11 0 0 11 11 11 9 Tetratricopeptide repeat TPR_8 PF13181.6 OAG37982.1 - 5.3e-38 126.1 20.4 6.2e-08 32.3 0.0 10.8 10 1 0 10 10 10 8 Tetratricopeptide repeat TPR_16 PF13432.6 OAG37982.1 - 1.5e-25 89.6 9.7 2.4e-05 24.9 0.1 6.7 6 1 1 7 7 7 5 Tetratricopeptide repeat TPR_14 PF13428.6 OAG37982.1 - 2.4e-25 87.0 16.3 1.4e-05 25.5 0.1 9.2 4 3 6 10 10 10 8 Tetratricopeptide repeat TPR_19 PF14559.6 OAG37982.1 - 8.1e-24 83.9 15.1 0.0001 22.7 0.1 7.4 6 2 1 7 7 7 5 Tetratricopeptide repeat TPR_11 PF13414.6 OAG37982.1 - 6.9e-23 80.1 30.6 2e-05 24.2 0.1 9.5 6 2 3 9 9 9 6 TPR repeat TPR_17 PF13431.6 OAG37982.1 - 1.4e-20 72.1 18.6 0.001 19.3 0.1 10.1 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_12 PF13424.6 OAG37982.1 - 2.3e-20 72.7 24.0 4.2e-05 23.8 0.6 8.2 4 2 3 7 7 7 5 Tetratricopeptide repeat TPR_6 PF13174.6 OAG37982.1 - 2.4e-19 68.6 19.9 0.00073 20.0 0.0 9.7 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_7 PF13176.6 OAG37982.1 - 2.9e-16 58.2 17.3 0.048 13.7 0.0 9.6 9 1 0 9 9 9 4 Tetratricopeptide repeat TPR_9 PF13371.6 OAG37982.1 - 2.4e-14 53.2 12.5 0.00076 19.6 0.2 6.7 2 2 6 8 8 8 6 Tetratricopeptide repeat ANAPC3 PF12895.7 OAG37982.1 - 3.8e-10 39.8 10.9 1.4e-06 28.4 1.7 4.5 4 1 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 OAG37982.1 - 6.1e-09 35.5 14.7 0.0082 15.4 1.4 5.6 1 1 4 5 5 5 4 Tetratricopeptide repeat TPR_21 PF09976.9 OAG37982.1 - 1.2e-07 31.6 8.1 0.021 14.6 0.0 4.4 4 2 0 5 5 4 3 Tetratricopeptide repeat-like domain Fis1_TPR_C PF14853.6 OAG37982.1 - 0.00014 21.8 0.7 0.063 13.3 0.0 4.2 4 0 0 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat DUF2225 PF09986.9 OAG37982.1 - 0.13 11.9 5.7 3.5 7.3 0.1 3.4 3 1 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) BTAD PF03704.17 OAG37982.1 - 0.15 12.5 7.7 12 6.3 0.5 3.8 3 1 0 3 3 3 0 Bacterial transcriptional activator domain ChAPs PF09295.10 OAG37982.1 - 0.25 10.3 3.6 0.92 8.4 0.3 3.0 3 1 1 4 4 4 0 ChAPs (Chs5p-Arf1p-binding proteins) DUF410 PF04190.13 OAG37982.1 - 0.28 10.9 4.3 5.5 6.7 0.4 3.1 1 1 1 2 2 2 0 Protein of unknown function (DUF410) TPR_10 PF13374.6 OAG37982.1 - 1.3 9.0 18.8 12 5.9 0.2 6.5 9 0 0 9 9 8 0 Tetratricopeptide repeat MIT PF04212.18 OAG37982.1 - 1.9 8.6 24.7 8.5 6.5 0.3 7.5 7 1 1 8 8 8 0 MIT (microtubule interacting and transport) domain TPR_20 PF14561.6 OAG37982.1 - 2.1 8.8 9.9 1.7 9.1 0.0 4.7 5 1 1 6 6 5 0 Tetratricopeptide repeat Proteasome PF00227.26 OAG37984.1 - 2.2e-56 190.4 0.0 2.4e-32 112.0 0.0 2.1 2 0 0 2 2 2 2 Proteasome subunit UQ_con PF00179.26 OAG37984.1 - 1.2e-36 125.5 0.0 2e-36 124.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OAG37984.1 - 0.12 12.1 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Prokaryotic E2 family B HhH-GPD PF00730.25 OAG37985.1 - 3.7e-17 62.7 0.0 8.6e-17 61.6 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 OAG37985.1 - 2.1e-07 30.4 0.0 4.7e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif SARAF PF06682.12 OAG37986.1 - 0.11 12.2 0.0 0.12 12.0 0.0 1.1 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis End3 PF12761.7 OAG37987.1 - 1.1e-65 221.6 2.4 1.8e-65 220.9 2.4 1.4 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_4 PF12763.7 OAG37987.1 - 6.3e-49 164.2 0.0 6.3e-46 154.6 0.1 2.4 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 OAG37987.1 - 1.1e-08 34.0 0.1 2.7e-07 29.6 0.2 2.6 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 OAG37987.1 - 4.2e-08 33.5 0.3 2.5e-06 27.8 0.0 3.1 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 OAG37987.1 - 1.3e-05 24.7 0.3 0.00044 19.9 0.2 3.0 3 0 0 3 3 3 1 EF-hand domain EF-hand_8 PF13833.6 OAG37987.1 - 1.8e-05 24.5 0.1 0.0032 17.3 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 OAG37987.1 - 0.0031 16.9 0.2 0.0096 15.4 0.2 1.9 1 0 0 1 1 1 1 EF hand Urb2 PF10441.9 OAG37988.1 - 4.5e-56 190.0 0.0 4.5e-56 190.0 0.0 3.8 4 1 0 4 4 4 1 Urb2/Npa2 family F-box_4 PF15966.5 OAG37989.1 - 0.018 14.9 0.0 0.037 13.9 0.0 1.4 1 0 0 1 1 1 0 F-box F-box PF00646.33 OAG37989.1 - 0.051 13.5 0.0 0.099 12.5 0.0 1.5 1 0 0 1 1 1 0 F-box domain BAR PF03114.18 OAG37990.1 - 1.5e-64 217.9 7.1 1.9e-64 217.6 7.1 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 OAG37990.1 - 2.2e-15 56.0 0.1 5.3e-15 54.7 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 OAG37990.1 - 2.1e-08 33.7 0.1 8.7e-08 31.7 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.6 OAG37990.1 - 2.2e-08 33.8 0.0 4.7e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain APG6_N PF17675.1 OAG37990.1 - 0.55 10.7 11.9 2.1 8.8 5.7 2.4 2 0 0 2 2 2 0 Apg6 coiled-coil region TMPIT PF07851.13 OAG37990.1 - 0.63 9.2 8.5 0.43 9.8 0.3 2.1 1 1 1 2 2 2 0 TMPIT-like protein BRE1 PF08647.11 OAG37990.1 - 1 9.5 11.5 0.6 10.2 1.2 2.7 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase Com_YlbF PF06133.11 OAG37990.1 - 6.1 7.5 12.5 5.6 7.6 0.4 2.7 2 1 0 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA Aminotran_5 PF00266.19 OAG37991.1 - 7.4e-91 304.9 0.0 9.2e-91 304.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 OAG37991.1 - 3e-07 29.9 0.0 6.9e-07 28.8 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 OAG37991.1 - 1.4e-06 27.9 0.0 2.6e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 OAG37991.1 - 5.6e-05 22.6 0.0 0.00018 20.9 0.0 1.8 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 OAG37991.1 - 0.01 14.4 0.0 0.016 13.8 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme TOH_N PF12549.8 OAG37991.1 - 0.19 11.6 0.9 0.55 10.2 0.9 1.8 1 0 0 1 1 1 0 Tyrosine hydroxylase N terminal ADH_zinc_N PF00107.26 OAG37992.1 - 3.6e-19 69.0 0.2 5.6e-19 68.4 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 OAG37992.1 - 2.1e-08 33.9 0.5 5e-08 32.7 0.5 1.6 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 OAG37992.1 - 3.3e-07 31.4 0.0 6.5e-07 30.5 0.0 1.4 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Pyr_redox_2 PF07992.14 OAG37992.1 - 0.0018 17.6 0.3 0.0095 15.2 0.3 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 OAG37992.1 - 0.017 14.7 0.0 0.025 14.2 0.0 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AlaDh_PNT_C PF01262.21 OAG37992.1 - 0.061 12.6 0.6 0.085 12.1 0.6 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Zn_clus PF00172.18 OAG37993.1 - 1.5e-08 34.6 12.5 2.5e-08 33.9 12.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAG37993.1 - 8.6e-06 25.0 0.6 2e-05 23.7 0.6 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain MSA-2c PF12238.8 OAG37993.1 - 4.6 7.2 5.8 7.8 6.4 5.8 1.3 1 0 0 1 1 1 0 Merozoite surface antigen 2c FAA_hydrolase PF01557.18 OAG37995.1 - 5.9e-43 147.1 0.0 1.3e-42 145.9 0.0 1.5 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 OAG37995.1 - 3.5e-26 91.5 0.0 1.4e-25 89.6 0.0 2.0 2 0 0 2 2 2 1 Fumarylacetoacetase N-terminal Fungal_trans PF04082.18 OAG37995.1 - 2.7e-18 66.0 2.7 5.7e-18 64.9 2.7 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Amidohydro_1 PF01979.20 OAG37996.1 - 1.2e-26 93.9 0.0 2.9e-26 92.6 0.0 1.7 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 OAG37996.1 - 1e-14 54.9 0.3 7.2e-08 32.3 0.0 3.0 2 1 1 3 3 3 2 Amidohydrolase family Cu-oxidase_4 PF02578.15 OAG37996.1 - 0.13 11.9 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Multi-copper polyphenol oxidoreductase laccase Urease_alpha PF00449.20 OAG37996.1 - 0.13 12.6 2.4 0.13 12.6 0.3 2.1 2 0 0 2 2 2 0 Urease alpha-subunit, N-terminal domain Transp_cyt_pur PF02133.15 OAG37997.1 - 2.5e-83 280.3 41.8 3.1e-83 280.0 41.8 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin PhyH PF05721.13 OAG37998.1 - 5.3e-20 72.6 0.1 5.3e-17 62.8 0.1 2.2 1 1 1 2 2 2 2 Phytanoyl-CoA dioxygenase (PhyH) GFA PF04828.14 OAG37999.1 - 2e-22 79.3 0.2 2.6e-22 79.0 0.2 1.1 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Tetraspanin PF00335.20 OAG38000.1 - 0.0025 17.5 0.0 0.003 17.3 0.0 1.2 1 0 0 1 1 1 1 Tetraspanin family Piwi PF02171.17 OAG38001.1 - 5.9e-75 252.3 0.0 2.8e-74 250.1 0.0 1.9 1 1 0 1 1 1 1 Piwi domain ArgoL1 PF08699.10 OAG38001.1 - 6.6e-12 44.9 1.4 4.6e-11 42.2 0.0 2.9 3 0 0 3 3 3 1 Argonaute linker 1 domain ArgoN PF16486.5 OAG38001.1 - 1.2e-11 45.4 0.1 2.2e-11 44.5 0.1 1.5 1 0 0 1 1 1 1 N-terminal domain of argonaute PAZ PF02170.22 OAG38001.1 - 1.9e-10 40.7 0.1 1.4e-09 37.9 0.0 2.4 2 1 0 2 2 2 1 PAZ domain ArgoL2 PF16488.5 OAG38001.1 - 6e-06 26.5 0.0 1.5e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 Argonaute linker 2 domain ArgoMid PF16487.5 OAG38001.1 - 0.013 15.8 0.0 0.031 14.5 0.0 1.7 1 0 0 1 1 1 0 Mid domain of argonaute CagZ PF09053.10 OAG38001.1 - 0.13 11.8 0.2 0.25 11.0 0.2 1.3 1 0 0 1 1 1 0 CagZ Abhydrolase_1 PF00561.20 OAG38002.1 - 6.8e-20 71.8 0.0 9.3e-20 71.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG38002.1 - 4e-11 43.9 0.0 4.8e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG38002.1 - 1.8e-07 30.7 0.0 6.1e-06 25.7 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 OAG38002.1 - 0.026 14.1 0.0 0.083 12.5 0.0 1.8 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Mito_carr PF00153.27 OAG38003.1 - 5.4e-35 119.2 6.2 2.1e-14 53.2 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein CFIA_Pcf11 PF11526.8 OAG38004.1 - 3e-07 30.8 0.0 7.6e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 Subunit of cleavage factor IA Pcf11 CTD_bind PF04818.13 OAG38004.1 - 1.1e-06 29.4 0.0 3.6e-06 27.7 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase II-binding domain. VHS PF00790.19 OAG38004.1 - 0.0018 18.1 0.0 0.0037 17.1 0.0 1.5 1 0 0 1 1 1 1 VHS domain zf-ISL3 PF14690.6 OAG38004.1 - 0.093 13.4 0.2 0.18 12.5 0.2 1.4 1 0 0 1 1 1 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-C2H2_11 PF16622.5 OAG38004.1 - 0.13 12.0 0.1 0.28 11.0 0.1 1.5 1 0 0 1 1 1 0 zinc-finger C2H2-type zf_UBZ PF18439.1 OAG38004.1 - 0.25 11.0 2.0 1.3 8.7 2.0 2.0 1 1 0 1 1 1 0 Ubiquitin-Binding Zinc Finger Inhibitor_I9 PF05922.16 OAG38005.1 - 0.0041 17.7 0.0 0.005 17.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase inhibitor I9 Glyco_transf_28 PF03033.20 OAG38005.1 - 0.11 12.6 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 28 N-terminal domain HOOK PF05622.12 OAG38006.1 - 1.9e-31 109.0 41.0 8.7e-27 93.6 25.7 2.6 2 1 0 2 2 2 2 HOOK protein CtsR_C PF17727.1 OAG38006.1 - 1.5e-05 25.0 3.8 0.11 12.6 0.3 2.6 2 0 0 2 2 2 2 CtsR C-terminal dimerization domain KxDL PF10241.9 OAG38006.1 - 0.0013 19.0 1.1 0.0013 19.0 1.1 5.5 5 1 1 6 6 6 2 Uncharacterized conserved protein HrpB7 PF09486.10 OAG38006.1 - 1 9.7 43.3 0.046 14.1 15.9 5.0 2 2 2 4 4 4 0 Bacterial type III secretion protein (HrpB7) Lactamase_B_2 PF12706.7 OAG38008.1 - 0.0083 15.7 0.9 0.031 13.8 0.9 1.9 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 OAG38008.1 - 0.067 13.2 4.5 0.12 12.3 4.5 1.8 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.6 OAG38008.1 - 0.09 12.7 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain NAD_binding_2 PF03446.15 OAG38009.1 - 3.8e-30 105.2 1.4 6.8e-30 104.3 1.4 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 OAG38009.1 - 4.2e-21 75.4 0.2 2.9e-20 72.7 0.0 2.2 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase OCD_Mu_crystall PF02423.15 OAG38009.1 - 6.1e-05 22.1 0.0 0.00013 21.1 0.0 1.5 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family F420_oxidored PF03807.17 OAG38009.1 - 0.047 14.3 0.1 0.14 12.8 0.1 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Fungal_trans PF04082.18 OAG38010.1 - 1.8e-10 40.3 0.6 7.2e-10 38.3 0.6 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 OAG38010.1 - 4.2e-07 30.1 12.0 0.0059 17.0 0.7 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OAG38010.1 - 2.4e-06 27.7 3.1 2.4e-06 27.7 3.1 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 OAG38010.1 - 5.4e-05 23.7 11.2 0.015 16.1 4.1 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OAG38010.1 - 0.021 15.1 3.6 0.085 13.2 1.2 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding PglL_A PF15864.5 OAG38010.1 - 2.2 8.1 5.1 0.27 11.0 0.2 2.1 2 0 0 2 2 2 0 Protein glycosylation ligase Lactamase_B PF00753.27 OAG38011.1 - 3.4e-11 43.5 3.8 1.1e-10 41.9 3.8 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OAG38011.1 - 0.038 13.5 1.2 0.098 12.2 0.9 1.9 1 1 0 1 1 1 0 Beta-lactamase superfamily domain MFS_1 PF07690.16 OAG38012.1 - 1e-38 133.2 21.4 1e-38 133.2 21.4 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 OAG38012.1 - 0.037 12.3 9.4 0.069 11.4 5.3 2.8 2 2 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Alpha-amylase PF00128.24 OAG38013.1 - 7.5e-24 84.9 1.5 1.9e-23 83.6 1.5 1.6 1 1 0 1 1 1 1 Alpha amylase, catalytic domain DUF1939 PF09154.10 OAG38013.1 - 0.01 16.0 0.1 0.022 14.9 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1939) Glyco_hydro_70 PF02324.16 OAG38013.1 - 0.011 14.0 0.0 4.7 5.3 0.0 2.9 3 0 0 3 3 3 0 Glycosyl hydrolase family 70 Tannase PF07519.11 OAG38014.1 - 8.2e-99 331.6 2.4 9.5e-99 331.4 2.4 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.21 OAG38014.1 - 9.4e-05 22.0 0.1 0.027 14.0 0.1 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 OAG38014.1 - 0.00013 21.3 0.0 0.0051 16.1 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 ADK PF00406.22 OAG38015.1 - 1.5e-59 200.4 0.0 2.1e-59 200.0 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 OAG38015.1 - 1.1e-21 77.7 0.2 2.9e-21 76.3 0.0 1.7 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 OAG38015.1 - 1.6e-16 60.0 0.0 3.2e-16 59.0 0.0 1.6 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 OAG38015.1 - 9.9e-05 22.9 0.0 0.00019 22.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 OAG38015.1 - 0.00056 20.1 0.0 0.00094 19.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain GFO_IDH_MocA PF01408.22 OAG38016.1 - 3.5e-14 53.6 0.0 5.9e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold RRM_1 PF00076.22 OAG38017.1 - 4.4e-18 64.9 0.0 5.2e-13 48.6 0.0 3.1 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.15 OAG38017.1 - 0.089 12.8 0.0 0.31 11.1 0.0 1.9 2 0 0 2 2 2 0 DbpA RNA binding domain GST_N_3 PF13417.6 OAG38018.1 - 3.1e-15 56.3 0.0 5.8e-15 55.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 OAG38018.1 - 7.5e-12 45.4 0.0 1.3e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OAG38018.1 - 3.9e-11 43.0 0.1 7.8e-11 42.0 0.1 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 OAG38018.1 - 4.1e-10 39.8 0.0 9.7e-10 38.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAG38018.1 - 8.5e-10 38.5 0.7 2.5e-09 37.0 0.1 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OAG38018.1 - 1.9e-06 28.0 0.0 3.1e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 OAG38018.1 - 0.0028 17.4 0.0 0.0056 16.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 OAG38018.1 - 0.14 13.0 0.0 0.34 11.7 0.0 1.8 1 1 0 1 1 1 0 Glutathione S-transferase N-terminal domain Abhydrolase_1 PF00561.20 OAG38019.1 - 2.2e-22 80.0 0.0 3.4e-15 56.4 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG38019.1 - 2.2e-19 70.9 2.4 2.7e-19 70.7 2.4 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG38019.1 - 6.9e-19 68.0 0.0 9.5e-19 67.6 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 OAG38019.1 - 4e-15 55.3 0.0 6.2e-15 54.7 0.0 1.3 1 1 0 1 1 1 1 Ndr family DUF1057 PF06342.12 OAG38019.1 - 1.6e-05 24.1 0.0 2e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Abhydrolase_5 PF12695.7 OAG38019.1 - 0.0041 16.9 0.0 2.7 7.8 0.0 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 OAG38019.1 - 0.0055 16.8 0.0 0.012 15.7 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein UPF0227 PF05728.12 OAG38019.1 - 0.072 13.0 0.0 0.46 10.4 0.0 2.2 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0227) FSH1 PF03959.13 OAG38019.1 - 0.18 11.5 0.0 0.36 10.5 0.0 1.5 2 0 0 2 2 2 0 Serine hydrolase (FSH1) BAAT_C PF08840.11 OAG38019.1 - 0.21 11.5 0.0 0.72 9.7 0.0 1.7 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal IGPS PF00218.21 OAG38020.1 - 2e-86 289.3 0.0 4.9e-86 288.0 0.0 1.6 1 1 0 1 1 1 1 Indole-3-glycerol phosphate synthase GATase PF00117.28 OAG38020.1 - 2.5e-46 157.8 0.0 4.9e-46 156.9 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I PRAI PF00697.22 OAG38020.1 - 3.4e-45 154.2 0.0 1.4e-40 139.2 0.0 2.6 2 1 1 3 3 3 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase Peptidase_C26 PF07722.13 OAG38020.1 - 8.2e-06 25.7 0.4 3.3e-05 23.7 0.4 1.9 1 1 0 1 1 1 1 Peptidase C26 Peripla_BP_2 PF01497.18 OAG38020.1 - 0.033 13.8 0.0 0.071 12.6 0.0 1.6 1 0 0 1 1 1 0 Periplasmic binding protein QRPTase_C PF01729.19 OAG38020.1 - 0.05 13.4 1.0 1.8 8.4 0.1 3.0 2 1 1 3 3 3 0 Quinolinate phosphoribosyl transferase, C-terminal domain p450 PF00067.22 OAG38021.1 - 9.2e-59 199.4 0.0 6.3e-58 196.6 0.0 1.8 2 0 0 2 2 2 1 Cytochrome P450 polyprenyl_synt PF00348.17 OAG38022.1 - 1.3e-65 221.0 0.0 1.6e-65 220.8 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Translin PF01997.16 OAG38022.1 - 0.017 15.1 0.0 0.039 13.9 0.0 1.6 1 1 0 1 1 1 0 Translin family CDC14 PF08045.11 OAG38023.1 - 1.4e-119 398.4 0.0 1.7e-119 398.1 0.0 1.0 1 0 0 1 1 1 1 Cell division control protein 14, SIN component Methyltransf_25 PF13649.6 OAG38024.1 - 3.2e-16 59.8 0.0 5.2e-16 59.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG38024.1 - 1.2e-15 57.9 0.0 2e-15 57.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG38024.1 - 4.7e-14 52.9 0.0 8.6e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG38024.1 - 1.2e-12 47.8 0.0 1.6e-12 47.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAG38024.1 - 5.1e-11 42.7 0.0 6.5e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 OAG38024.1 - 3.9e-09 36.2 0.0 4.6e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 OAG38024.1 - 9.7e-07 28.4 0.0 1.5e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 OAG38024.1 - 1.4e-06 28.3 0.0 1.7e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 OAG38024.1 - 3.3e-05 23.5 0.0 0.00011 21.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_5 PF01795.19 OAG38024.1 - 0.00012 21.7 0.0 0.00096 18.7 0.0 1.9 1 1 1 2 2 2 1 MraW methylase family PrmA PF06325.13 OAG38024.1 - 0.00012 21.6 0.0 0.00018 21.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.18 OAG38024.1 - 0.00014 21.2 0.0 0.00019 20.8 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_18 PF12847.7 OAG38024.1 - 0.00048 20.1 0.0 0.00089 19.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_33 PF10017.9 OAG38024.1 - 0.00061 19.0 0.0 0.0019 17.4 0.0 1.7 2 0 0 2 2 2 1 Histidine-specific methyltransferase, SAM-dependent Methyltransf_32 PF13679.6 OAG38024.1 - 0.0021 18.0 0.0 0.0031 17.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 OAG38024.1 - 0.013 15.7 0.0 0.09 12.9 0.0 2.1 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_PK PF05891.12 OAG38024.1 - 0.015 14.8 0.0 0.021 14.3 0.0 1.2 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Methyltransf_8 PF05148.15 OAG38024.1 - 0.034 14.0 0.0 0.78 9.5 0.0 2.1 1 1 0 1 1 1 0 Hypothetical methyltransferase RrnaAD PF00398.20 OAG38024.1 - 0.036 13.1 0.0 0.045 12.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_7 PF03492.15 OAG38024.1 - 0.062 12.5 0.0 0.16 11.2 0.0 1.6 2 0 0 2 2 2 0 SAM dependent carboxyl methyltransferase AviRa PF11599.8 OAG38024.1 - 0.091 12.2 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 RRNA methyltransferase AviRa TehB PF03848.14 OAG38024.1 - 0.098 12.0 0.0 0.17 11.3 0.0 1.5 1 1 0 1 1 1 0 Tellurite resistance protein TehB AhpC-TSA_2 PF13911.6 OAG38026.1 - 1.1e-12 48.0 0.0 2.4e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme Fungal_trans PF04082.18 OAG38027.1 - 1.1e-15 57.4 0.2 1.6e-15 56.9 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain TRI12 PF06609.13 OAG38028.1 - 2.4e-48 165.0 18.3 3e-48 164.6 18.3 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG38028.1 - 1.8e-14 53.4 58.6 5.5e-14 51.9 52.0 2.8 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG38028.1 - 1.9e-10 40.2 11.0 1.9e-10 40.2 11.0 3.0 3 0 0 3 3 3 1 Sugar (and other) transporter SH3_10 PF17902.1 OAG38029.1 - 0.12 12.5 0.0 10 6.3 0.0 2.6 2 0 0 2 2 2 0 SH3 domain UPF1_Zn_bind PF09416.10 OAG38030.1 - 1.4e-72 242.6 3.8 1.7e-72 242.4 2.3 1.9 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.6 OAG38030.1 - 2.8e-60 203.4 0.0 6.1e-60 202.3 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 OAG38030.1 - 2.3e-54 184.9 2.5 6.9e-31 108.0 0.2 2.4 1 1 1 2 2 2 2 AAA domain DUF5599 PF18141.1 OAG38030.1 - 2.2e-33 114.3 0.0 4.2e-33 113.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5599) AAA_30 PF13604.6 OAG38030.1 - 2.5e-13 50.2 0.2 3e-12 46.6 0.2 2.4 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OAG38030.1 - 4.4e-11 43.3 0.0 2.6e-10 40.8 0.0 2.3 2 1 0 2 2 2 1 AAA domain ResIII PF04851.15 OAG38030.1 - 5.7e-06 26.4 0.0 1.1e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 OAG38030.1 - 0.00017 21.4 0.1 0.45 10.2 0.0 2.8 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 OAG38030.1 - 0.00054 19.3 0.2 0.009 15.3 0.0 2.5 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.14 OAG38030.1 - 0.0012 18.8 0.0 0.0024 17.7 0.0 1.6 1 0 0 1 1 1 1 Helicase UvrD-helicase PF00580.21 OAG38030.1 - 0.0014 18.2 0.1 0.036 13.6 0.0 2.6 2 1 1 3 3 3 1 UvrD/REP helicase N-terminal domain PIF1 PF05970.14 OAG38030.1 - 0.0022 17.2 0.1 0.55 9.3 0.0 2.2 2 0 0 2 2 2 2 PIF1-like helicase DEAD PF00270.29 OAG38030.1 - 0.006 16.4 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_10 PF12846.7 OAG38030.1 - 0.033 13.1 0.0 0.051 12.5 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain Ribosomal_S13_N PF08069.12 OAG38030.1 - 0.074 13.1 0.0 0.2 11.7 0.0 1.7 1 0 0 1 1 1 0 Ribosomal S13/S15 N-terminal domain AAA_22 PF13401.6 OAG38030.1 - 0.12 12.6 0.0 0.38 11.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 OAG38030.1 - 0.15 11.4 0.0 0.44 9.8 0.0 1.8 2 0 0 2 2 2 0 KaiC zf-UBP PF02148.19 OAG38030.1 - 1.6 9.1 7.0 4.3 7.7 7.0 1.7 1 0 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein Brix PF04427.18 OAG38031.1 - 4.8e-30 105.1 0.1 6.1e-30 104.8 0.1 1.1 1 0 0 1 1 1 1 Brix domain Nup188_C PF18378.1 OAG38033.1 - 2.4e-70 237.2 0.5 5.4e-70 236.1 0.5 1.6 1 0 0 1 1 1 1 Nuclear pore protein NUP188 C-terminal domain Nup188 PF10487.9 OAG38033.1 - 9.4e-52 176.1 0.6 1.7e-39 135.5 1.2 2.6 3 0 0 3 3 3 2 Nucleoporin subcomplex protein binding to Pom34 DUF1904 PF08921.11 OAG38033.1 - 0.17 12.2 0.0 0.6 10.4 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1904) AMP-binding PF00501.28 OAG38034.1 - 8.3e-88 294.8 0.0 1.1e-87 294.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG38034.1 - 8.2e-16 58.8 0.3 2.1e-15 57.4 0.3 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Fungal_trans PF04082.18 OAG38035.1 - 7.2e-15 54.7 0.1 1.1e-14 54.2 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Nebulin PF00880.18 OAG38035.1 - 0.026 14.5 0.2 0.059 13.3 0.2 1.6 1 0 0 1 1 1 0 Nebulin repeat CoA_transf_3 PF02515.17 OAG38036.1 - 7.8e-36 123.9 0.0 4.1e-35 121.6 0.0 2.0 2 0 0 2 2 2 1 CoA-transferase family III AMP-binding PF00501.28 OAG38037.1 - 1.9e-73 247.5 0.0 2.3e-73 247.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG38037.1 - 2.6e-16 60.3 0.0 6.8e-16 59.0 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain TauD PF02668.16 OAG38038.1 - 2e-58 198.3 0.1 2.4e-58 198.0 0.1 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Sugar_tr PF00083.24 OAG38039.1 - 1.1e-79 268.5 18.4 1.2e-79 268.3 18.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG38039.1 - 1.7e-21 76.5 44.3 1.9e-15 56.7 21.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2070 PF09843.9 OAG38039.1 - 0.65 8.2 8.8 0.0079 14.5 1.5 1.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) DUF4188 PF13826.6 OAG38040.1 - 2e-31 108.8 0.2 3.1e-31 108.2 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4188) DUF3291 PF11695.8 OAG38040.1 - 0.00093 18.9 0.1 0.0016 18.2 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3291) Dehydratase_hem PF13816.6 OAG38040.1 - 0.0032 16.9 0.5 0.0047 16.4 0.5 1.2 1 0 0 1 1 1 1 Haem-containing dehydratase FA_desaturase PF00487.24 OAG38041.1 - 1.4e-23 84.0 21.5 3.4e-23 82.8 21.5 1.5 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 OAG38041.1 - 4.6e-07 30.1 0.0 3.8e-06 27.1 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3474) TRAPPC10 PF12584.8 OAG38042.1 - 1.1e-10 41.4 0.0 2.5e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 TetR_C_30 PF17939.1 OAG38042.1 - 0.0045 17.2 0.0 0.016 15.5 0.0 1.9 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain RVT_1 PF00078.27 OAG38043.1 - 0.00022 20.8 0.0 0.00045 19.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SWIM PF04434.17 OAG38044.1 - 4.9e-05 22.9 2.6 0.049 13.3 0.0 2.3 2 0 0 2 2 2 2 SWIM zinc finger MitMem_reg PF13012.6 OAG38045.1 - 3e-37 127.5 0.1 5e-37 126.8 0.1 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 OAG38045.1 - 1.1e-31 109.3 0.5 1.4e-30 105.7 0.0 2.2 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease BSP_II PF05432.11 OAG38045.1 - 0.018 14.7 11.3 0.027 14.2 11.3 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Connexin PF00029.19 OAG38045.1 - 0.028 14.2 0.8 0.048 13.4 0.8 1.3 1 0 0 1 1 1 0 Connexin DUF2999 PF11212.8 OAG38045.1 - 0.057 13.7 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2999) FAM176 PF14851.6 OAG38045.1 - 0.27 10.9 2.1 0.57 9.8 2.1 1.5 1 0 0 1 1 1 0 FAM176 family p450 PF00067.22 OAG38046.1 - 3.7e-60 204.0 0.0 1.3e-57 195.6 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 Cu-oxidase_2 PF07731.14 OAG38047.1 - 1.4e-37 128.4 7.7 7.7e-36 122.9 0.5 3.2 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 OAG38047.1 - 8.2e-36 122.6 2.8 8.2e-36 122.6 2.8 3.3 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.22 OAG38047.1 - 2.5e-28 99.2 3.5 6.7e-28 97.8 0.1 3.1 3 0 0 3 3 3 1 Multicopper oxidase Fungal_trans PF04082.18 OAG38048.1 - 0.0002 20.5 3.0 0.00033 19.8 3.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cas_Csy4 PF09618.10 OAG38049.1 - 0.13 12.4 0.1 0.13 12.4 0.1 1.8 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Csy4) DUF5320 PF17253.2 OAG38049.1 - 0.21 12.7 5.3 0.14 13.3 1.4 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5320) Keratin_2_head PF16208.5 OAG38049.1 - 0.31 11.2 12.5 0.49 10.5 12.5 1.2 1 0 0 1 1 1 0 Keratin type II head Pkinase PF00069.25 OAG38050.1 - 8e-19 68.0 0.0 1.5e-18 67.1 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG38050.1 - 6.2e-05 22.4 0.0 6.7e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OAG38050.1 - 0.041 13.8 0.0 0.058 13.3 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ank_4 PF13637.6 OAG38051.1 - 6.3e-12 45.8 0.1 0.0028 18.2 0.0 4.3 4 2 1 5 5 5 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 OAG38051.1 - 5.6e-11 42.9 0.0 0.00028 21.4 0.0 2.6 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OAG38051.1 - 1.4e-09 37.4 0.0 0.56 11.0 0.0 5.4 6 0 0 6 6 6 2 Ankyrin repeat Ank_5 PF13857.6 OAG38051.1 - 6.1e-07 29.6 0.0 0.17 12.3 0.0 4.4 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 OAG38051.1 - 0.00083 19.7 0.0 8.6 7.0 0.0 4.7 5 0 0 5 5 5 1 Ankyrin repeat SnoaL_2 PF12680.7 OAG38052.1 - 0.00015 22.3 0.1 0.00035 21.1 0.1 1.6 1 1 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 OAG38052.1 - 0.0011 19.4 0.1 0.0014 19.0 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_4 PF13577.6 OAG38052.1 - 0.03 14.5 0.0 0.048 13.8 0.0 1.3 1 0 0 1 1 1 0 SnoaL-like domain FAA_hydrolase PF01557.18 OAG38053.1 - 2.6e-53 180.9 0.0 3.3e-53 180.6 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family p450 PF00067.22 OAG38054.1 - 5.7e-60 203.4 0.0 7e-60 203.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_3 PF01494.19 OAG38055.1 - 3.5e-18 66.0 1.7 2.2e-17 63.4 1.7 2.1 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 OAG38055.1 - 4e-07 29.6 0.4 8e-05 22.0 0.1 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAG38055.1 - 1.6e-05 25.4 0.4 0.004 17.7 0.2 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAG38055.1 - 3.8e-05 23.4 3.7 0.029 14.0 0.7 2.3 1 1 1 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAG38055.1 - 5e-05 23.5 0.2 0.00014 22.0 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 OAG38055.1 - 0.00016 20.9 0.3 0.0019 17.4 0.2 2.2 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 OAG38055.1 - 0.0014 17.4 0.1 0.024 13.4 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 OAG38055.1 - 0.0093 15.1 0.1 0.014 14.5 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 OAG38055.1 - 0.024 13.9 0.0 0.048 13.0 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 OAG38055.1 - 0.12 11.5 0.2 0.22 10.7 0.2 1.3 1 0 0 1 1 1 0 Thi4 family FAD_binding_3 PF01494.19 OAG38056.1 - 1.4e-69 235.0 0.0 1.9e-69 234.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 OAG38056.1 - 4.5e-05 22.8 0.0 0.0038 16.5 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAG38056.1 - 6.2e-05 23.5 0.1 0.0021 18.6 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG38056.1 - 0.02 15.1 0.1 0.051 13.8 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAG38056.1 - 0.022 14.4 3.4 0.77 9.3 0.0 3.4 2 1 1 4 4 4 0 FAD dependent oxidoreductase HI0933_like PF03486.14 OAG38056.1 - 0.061 12.0 0.0 0.14 10.8 0.0 1.5 1 0 0 1 1 1 0 HI0933-like protein FAD_oxidored PF12831.7 OAG38056.1 - 0.07 12.5 0.2 0.29 10.4 0.2 2.0 1 1 0 1 1 1 0 FAD dependent oxidoreductase Glu_dehyd_C PF16912.5 OAG38056.1 - 0.11 11.9 0.0 0.43 10.0 0.0 1.9 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus 2-Hacid_dh_C PF02826.19 OAG38056.1 - 0.12 11.7 0.0 0.37 10.1 0.0 1.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 OAG38056.1 - 0.14 11.4 0.0 0.24 10.6 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase LpxI_N PF17930.1 OAG38056.1 - 0.17 11.8 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 LpxI N-terminal domain NAD_binding_7 PF13241.6 OAG38056.1 - 0.17 12.3 0.0 0.75 10.3 0.0 2.1 2 1 0 2 2 2 0 Putative NAD(P)-binding Shikimate_DH PF01488.20 OAG38056.1 - 0.21 11.6 0.4 3.9 7.5 0.0 2.9 4 0 0 4 4 4 0 Shikimate / quinate 5-dehydrogenase Glyoxalase PF00903.25 OAG38057.1 - 1.5e-12 47.8 0.0 2e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily p450 PF00067.22 OAG38058.1 - 3.8e-63 213.9 0.0 4.3e-63 213.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short_C2 PF13561.6 OAG38059.1 - 3.6e-40 138.0 0.4 9.1e-40 136.7 0.4 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG38059.1 - 1.2e-33 116.2 0.1 2e-33 115.5 0.1 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG38059.1 - 7.7e-07 29.2 0.0 1.2e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG38059.1 - 0.027 14.0 0.2 0.51 9.8 0.1 2.5 1 1 1 2 2 2 0 NAD dependent epimerase/dehydratase family Sugar_tr PF00083.24 OAG38060.1 - 2.2e-79 267.4 25.1 2.5e-79 267.2 25.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG38060.1 - 1.8e-32 112.7 65.5 5.1e-27 94.7 29.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily SnoaL_3 PF13474.6 OAG38061.1 - 9.1e-10 38.8 0.1 1.4e-09 38.2 0.1 1.3 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 OAG38061.1 - 0.00024 21.5 0.0 0.0004 20.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) Fungal_trans PF04082.18 OAG38062.1 - 5e-11 42.1 0.5 8.7e-11 41.3 0.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain COQ9 PF08511.11 OAG38062.1 - 0.12 12.2 0.1 0.29 10.9 0.1 1.6 1 0 0 1 1 1 0 COQ9 EthD PF07110.11 OAG38063.1 - 2.7e-28 98.9 0.2 2.7e-14 54.1 0.0 2.1 2 0 0 2 2 2 2 EthD domain MmlI PF09448.10 OAG38063.1 - 3.5e-21 75.8 0.2 1.1e-09 38.8 0.1 2.1 2 0 0 2 2 2 2 Methylmuconolactone methyl-isomerase adh_short_C2 PF13561.6 OAG38065.1 - 2.9e-37 128.5 0.1 1.2e-34 119.9 0.1 2.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG38065.1 - 7.4e-35 120.2 0.0 2e-34 118.8 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase FMO-like PF00743.19 OAG38065.1 - 5.2e-12 45.0 0.6 4e-10 38.7 0.2 2.7 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like KR PF08659.10 OAG38065.1 - 3.8e-11 43.2 0.0 6.9e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 KR domain K_oxygenase PF13434.6 OAG38065.1 - 1.5e-06 27.6 0.2 0.16 11.1 0.0 3.7 4 0 0 4 4 4 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 OAG38065.1 - 1.8e-05 24.9 0.0 6.2e-05 23.2 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAG38065.1 - 8.1e-05 22.0 0.0 0.03 13.6 0.0 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAG38065.1 - 0.0074 16.3 0.0 0.09 12.8 0.0 2.6 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 OAG38065.1 - 0.031 13.5 0.0 0.18 11.1 0.0 2.2 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.19 OAG38066.1 - 1.7e-62 211.4 0.0 2.2e-62 211.1 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAG38066.1 - 4.2e-32 111.6 0.1 8.1e-32 110.7 0.1 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 OAG38066.1 - 0.00023 20.4 1.6 0.0013 17.9 1.5 1.9 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 OAG38066.1 - 0.00053 20.2 0.3 0.00053 20.2 0.3 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 OAG38066.1 - 0.0016 17.5 0.3 0.0033 16.5 0.3 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 OAG38066.1 - 0.002 17.8 6.0 0.005 16.5 4.3 2.3 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG38066.1 - 0.0048 16.2 0.0 0.01 15.1 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAG38066.1 - 0.0052 16.0 0.0 0.02 14.1 0.0 1.8 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 OAG38066.1 - 0.11 11.2 0.6 0.4 9.3 0.1 1.9 2 0 0 2 2 2 0 HI0933-like protein Trp_halogenase PF04820.14 OAG38066.1 - 0.23 10.3 0.1 0.34 9.7 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase RdRP PF05183.12 OAG38067.1 - 2.4e-172 574.6 0.0 3.1e-172 574.3 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase Cys_Met_Meta_PP PF01053.20 OAG38068.1 - 8.4e-62 208.9 0.0 2.2e-61 207.5 0.0 1.7 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 OAG38068.1 - 0.017 14.1 0.0 0.03 13.3 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V Aminotran_1_2 PF00155.21 OAG38068.1 - 0.024 13.8 0.0 0.04 13.1 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II SelA PF03841.13 OAG38068.1 - 0.079 11.9 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 L-seryl-tRNA selenium transferase 4HBT PF03061.22 OAG38070.1 - 2.5e-10 40.6 0.0 3.5e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 OAG38070.1 - 0.00012 22.5 0.0 0.00015 22.1 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT_2 PF13279.6 OAG38070.1 - 0.07 13.6 0.0 0.082 13.4 0.0 1.2 1 0 0 1 1 1 0 Thioesterase-like superfamily MFS_1 PF07690.16 OAG38072.1 - 9.9e-19 67.5 82.4 4.8e-18 65.2 51.6 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 OAG38072.1 - 5.4e-18 64.7 23.3 7.6e-18 64.3 23.3 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ThrE PF06738.12 OAG38072.1 - 0.039 13.3 0.1 0.039 13.3 0.1 3.7 4 1 0 4 4 4 0 Putative threonine/serine exporter DUF4017 PF13209.6 OAG38072.1 - 0.11 12.4 5.6 0.15 12.0 1.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4017) Aminotran_3 PF00202.21 OAG38073.1 - 8e-120 400.2 0.0 9.9e-120 399.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 OAG38073.1 - 0.00035 19.9 0.0 0.0018 17.5 0.0 1.8 1 1 1 2 2 2 1 Aminotransferase class I and II DUF3301 PF11743.8 OAG38073.1 - 0.11 12.2 0.0 0.26 11.0 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3301) Peroxidase_2 PF01328.17 OAG38074.1 - 9.1e-44 150.2 0.0 1.2e-43 149.8 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 Ribonuclease_T2 PF00445.18 OAG38074.1 - 0.18 12.1 0.0 0.26 11.5 0.0 1.1 1 0 0 1 1 1 0 Ribonuclease T2 family An_peroxidase PF03098.15 OAG38075.1 - 6.8e-118 394.5 0.0 8.4e-118 394.2 0.0 1.0 1 0 0 1 1 1 1 Animal haem peroxidase zf-CCCH PF00642.24 OAG38076.1 - 3.2e-08 33.3 20.0 3e-07 30.2 2.5 3.1 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.22 OAG38076.1 - 0.0015 18.3 0.0 0.0023 17.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Torus PF16131.5 OAG38076.1 - 0.0044 17.7 1.6 0.5 11.1 0.2 2.5 2 0 0 2 2 2 2 Torus domain zf_CCCH_4 PF18345.1 OAG38076.1 - 0.0058 16.7 3.3 0.0058 16.7 3.3 3.3 3 0 0 3 3 3 1 Zinc finger domain zf-CCCH_3 PF15663.5 OAG38076.1 - 3.1 8.1 8.4 0.46 10.7 1.3 2.4 2 2 0 2 2 2 0 Zinc-finger containing family Glyco_hydro_31 PF01055.26 OAG38077.1 - 6.9e-56 190.3 6.6 9.8e-56 189.8 6.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 COX5B PF01215.19 OAG38078.1 - 5.1e-51 171.7 0.0 7.2e-51 171.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb 7TM_GPCR_Sra PF02117.16 OAG38079.1 - 0.031 13.1 0.3 0.054 12.3 0.1 1.4 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Sra MgtE PF01769.16 OAG38079.1 - 0.096 13.1 1.2 0.17 12.3 1.2 1.3 1 0 0 1 1 1 0 Divalent cation transporter CcmF_C PF16327.5 OAG38079.1 - 0.12 11.7 0.8 0.18 11.1 0.8 1.1 1 0 0 1 1 1 0 Cytochrome c-type biogenesis protein CcmF C-terminal Aldo_ket_red PF00248.21 OAG38080.1 - 1.2e-38 133.0 0.0 9.5e-28 97.2 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family ER_lumen_recept PF00810.18 OAG38081.1 - 1.3e-44 152.6 9.6 2.1e-44 151.9 9.6 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.14 OAG38081.1 - 0.0079 15.9 8.2 0.03 14.1 0.0 3.2 3 1 0 3 3 3 2 PQ loop repeat Amidase PF01425.21 OAG38082.1 - 6.9e-28 97.8 0.2 1.2e-27 97.0 0.2 1.3 1 0 0 1 1 1 1 Amidase YfcL PF08891.11 OAG38082.1 - 0.018 15.4 0.0 0.18 12.1 0.0 2.3 2 0 0 2 2 2 0 YfcL protein Aldo_ket_red PF00248.21 OAG38083.1 - 5.5e-58 196.5 0.0 6.3e-58 196.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Glyco_hydro_76 PF03663.14 OAG38084.1 - 1.5e-22 80.6 4.2 3.8e-22 79.3 0.2 3.0 2 1 0 2 2 2 1 Glycosyl hydrolase family 76 FAA_hydrolase PF01557.18 OAG38085.1 - 1.4e-51 175.3 0.0 1.9e-51 174.8 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 OAG38085.1 - 3.3e-25 88.3 0.0 2.2e-24 85.7 0.0 2.0 2 0 0 2 2 2 1 Fumarylacetoacetase N-terminal Nha1_C PF08619.10 OAG38086.1 - 0.64 9.2 2.3 0.69 9.1 0.2 1.9 2 0 0 2 2 2 0 Alkali metal cation/H+ antiporter Nha1 C terminus PAF-AH_p_II PF03403.13 OAG38087.1 - 5.4e-56 189.7 0.0 4e-52 177.0 0.0 2.8 2 1 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 OAG38087.1 - 8.2e-08 31.5 0.0 2.3e-06 26.7 0.0 2.3 2 0 0 2 2 2 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 OAG38087.1 - 0.00016 21.0 0.1 0.028 13.7 0.1 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Chlorophyllase PF07224.11 OAG38087.1 - 0.00075 18.6 0.0 0.0021 17.1 0.0 1.6 2 0 0 2 2 2 1 Chlorophyllase DLH PF01738.18 OAG38087.1 - 0.11 12.0 0.0 1.7 8.1 0.0 2.3 2 1 0 3 3 3 0 Dienelactone hydrolase family Beta-lactamase PF00144.24 OAG38088.1 - 3e-64 217.4 0.1 3.4e-64 217.2 0.1 1.0 1 0 0 1 1 1 1 Beta-lactamase AA_permease PF00324.21 OAG38089.1 - 2.8e-121 405.4 33.0 3.2e-121 405.3 33.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAG38089.1 - 2.5e-33 115.6 37.1 3.2e-33 115.2 37.1 1.0 1 0 0 1 1 1 1 Amino acid permease p450 PF00067.22 OAG38090.1 - 9.8e-62 209.2 0.0 1.5e-61 208.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 FAD-oxidase_C PF02913.19 OAG38090.1 - 6.4e-55 186.5 0.1 1e-54 185.8 0.1 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 OAG38090.1 - 3.3e-33 114.3 0.0 6.3e-33 113.4 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Pkinase PF00069.25 OAG38091.1 - 3.2e-09 36.5 0.0 1.2e-08 34.6 0.0 1.7 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG38091.1 - 1.9e-05 24.1 0.0 3e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase FAD_binding_3 PF01494.19 OAG38092.1 - 1.4e-79 267.9 0.0 1.9e-79 267.4 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain bMG5 PF17972.1 OAG38092.1 - 0.14 12.5 0.0 0.29 11.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial Alpha-2-macroglobulin MG5 domain Fungal_trans PF04082.18 OAG38093.1 - 2.1e-10 40.1 0.7 3.4e-10 39.4 0.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 OAG38094.1 - 3.1e-20 72.4 32.0 4.7e-20 71.8 32.0 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Mito_carr PF00153.27 OAG38095.1 - 1.2e-52 175.8 4.8 1.6e-19 69.6 0.1 3.9 3 1 1 4 4 4 3 Mitochondrial carrier protein RIIa PF02197.17 OAG38095.1 - 0.019 14.6 0.0 1.2 8.9 0.0 2.4 2 0 0 2 2 2 0 Regulatory subunit of type II PKA R-subunit CoA_transf_3 PF02515.17 OAG38096.1 - 4.5e-111 371.5 0.0 5.3e-111 371.3 0.0 1.1 1 0 0 1 1 1 1 CoA-transferase family III HPIP_like PF18524.1 OAG38096.1 - 0.14 12.0 0.1 0.25 11.2 0.1 1.3 1 0 0 1 1 1 0 High potential iron-sulfur protein like CoA_trans PF01144.23 OAG38097.1 - 2.7e-96 321.2 0.2 1.5e-59 201.0 0.0 2.0 2 0 0 2 2 2 2 Coenzyme A transferase Lyase_1 PF00206.20 OAG38098.1 - 1e-45 156.5 0.1 3.3e-45 154.8 0.1 1.7 1 1 0 1 1 1 1 Lyase ADSL_C PF10397.9 OAG38098.1 - 1.6e-19 70.2 0.0 8.5e-19 67.9 0.0 2.2 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminus HTH_24 PF13412.6 OAG38098.1 - 0.11 12.1 0.0 0.29 10.7 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding YgaB PF14182.6 OAG38098.1 - 0.15 12.5 0.1 1.9 8.9 0.1 2.5 2 0 0 2 2 2 0 YgaB-like protein NmrA PF05368.13 OAG38099.1 - 8.7e-45 153.1 0.0 1.1e-44 152.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG38099.1 - 9.7e-14 51.7 0.0 2.1e-13 50.6 0.0 1.5 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 OAG38099.1 - 0.00077 19.0 0.0 0.0013 18.3 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Calpain_III PF01067.22 OAG38099.1 - 0.12 12.6 0.0 0.23 11.7 0.0 1.3 1 0 0 1 1 1 0 Calpain large subunit, domain III Dioxygenase_C PF00775.21 OAG38100.1 - 3.6e-37 127.6 0.0 4.6e-37 127.2 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 OAG38100.1 - 9.5e-29 99.1 0.0 1.6e-28 98.4 0.0 1.4 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 OAG38100.1 - 0.00073 19.8 0.0 0.0018 18.5 0.0 1.7 1 1 0 1 1 1 1 Carboxypeptidase regulatory-like domain DUF1416 PF07210.12 OAG38100.1 - 0.031 14.2 0.0 5.1 7.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1416) DUF1719 PF08224.11 OAG38100.1 - 0.13 11.4 0.1 0.19 10.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1719) DUF2202 PF09968.9 OAG38100.1 - 0.13 12.1 0.1 0.78 9.6 0.0 2.2 3 0 0 3 3 3 0 Uncharacterized protein domain (DUF2202) Nitroreductase PF00881.24 OAG38101.1 - 2.1e-12 47.4 0.0 2.4e-12 47.2 0.0 1.0 1 0 0 1 1 1 1 Nitroreductase family Thiolase_N PF00108.23 OAG38102.1 - 1.3e-74 250.9 0.2 3.2e-73 246.3 0.0 2.0 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 OAG38102.1 - 2.1e-43 146.9 0.1 5.5e-43 145.5 0.1 1.7 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 OAG38102.1 - 9.3e-06 25.4 0.3 2.3e-05 24.1 0.3 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Prolactin_RP PF15172.6 OAG38102.1 - 0.12 12.0 0.0 0.31 10.7 0.0 1.6 1 0 0 1 1 1 0 Prolactin-releasing peptide Fe-ADH PF00465.19 OAG38103.1 - 2.7e-60 204.1 0.0 3.5e-60 203.8 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 OAG38103.1 - 9.4e-09 35.3 0.0 0.00029 20.6 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Fungal_trans PF04082.18 OAG38104.1 - 2e-13 50.0 0.3 9.2e-13 47.8 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain p450 PF00067.22 OAG38105.1 - 1.9e-45 155.5 0.0 1.2e-42 146.3 0.0 2.4 2 1 0 2 2 2 2 Cytochrome P450 MFS_1 PF07690.16 OAG38106.1 - 4.3e-40 137.7 29.9 2.2e-39 135.4 24.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG38106.1 - 4e-14 52.3 10.4 4e-14 52.3 10.4 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter PUCC PF03209.15 OAG38106.1 - 0.00055 19.0 9.7 0.00055 19.0 9.7 2.5 3 0 0 3 3 3 1 PUCC protein OATP PF03137.20 OAG38106.1 - 0.02 13.2 7.3 0.26 9.5 7.4 2.6 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family PSI_PsaJ PF01701.18 OAG38106.1 - 0.058 13.9 0.1 0.18 12.3 0.1 1.8 1 0 0 1 1 1 0 Photosystem I reaction centre subunit IX / PsaJ CoA_binding_3 PF13727.6 OAG38106.1 - 2.7 8.0 7.2 0.2 11.7 0.3 2.4 3 0 0 3 3 3 0 CoA-binding domain Fungal_trans_2 PF11951.8 OAG38107.1 - 2.2e-53 181.4 0.7 2.7e-53 181.2 0.7 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG38107.1 - 1.1e-05 25.4 15.7 2e-05 24.6 15.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fe_dep_repr_C PF02742.15 OAG38107.1 - 0.064 13.3 0.0 0.33 11.1 0.0 2.2 2 0 0 2 2 2 0 Iron dependent repressor, metal binding and dimerisation domain Rep_fac-A_C PF08646.10 OAG38107.1 - 0.29 10.9 1.9 0.6 9.8 1.9 1.4 1 0 0 1 1 1 0 Replication factor-A C terminal domain HRI1 PF16815.5 OAG38108.1 - 3.1e-29 102.3 0.1 4.6e-29 101.8 0.1 1.2 1 0 0 1 1 1 1 Protein HRI1 adh_short PF00106.25 OAG38109.1 - 2.7e-22 79.2 0.0 2.2e-17 63.2 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAG38109.1 - 1.6e-14 54.0 0.0 1.1e-10 41.5 0.0 2.2 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG38109.1 - 3.7e-10 40.0 0.0 5.5e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG38109.1 - 0.03 13.8 0.0 0.053 13.0 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family FlgD_ig PF13860.6 OAG38109.1 - 0.048 13.5 0.5 0.084 12.8 0.5 1.4 1 0 0 1 1 1 0 FlgD Ig-like domain Amidase PF01425.21 OAG38110.1 - 9.1e-88 295.2 0.0 1.2e-87 294.7 0.0 1.2 1 0 0 1 1 1 1 Amidase DUF2235 PF09994.9 OAG38111.1 - 3.5e-82 276.0 0.0 4.6e-82 275.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) PAP_central PF04928.17 OAG38112.1 - 8.7e-99 329.5 0.0 1.1e-98 329.1 0.0 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 OAG38112.1 - 2.6e-48 163.9 0.1 4.3e-48 163.2 0.1 1.3 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 OAG38112.1 - 1.6e-09 38.0 0.0 4.3e-09 36.5 0.0 1.8 1 1 0 1 1 1 1 Nucleotidyltransferase domain Aconitase_B_N PF11791.8 OAG38112.1 - 0.14 12.2 0.1 0.31 11.1 0.1 1.5 1 0 0 1 1 1 0 Aconitate B N-terminal domain Pro_CA PF00484.19 OAG38113.1 - 1.5e-14 54.6 0.1 3.6e-14 53.3 0.1 1.6 1 1 0 1 1 1 1 Carbonic anhydrase Sipho_Gp37 PF14594.6 OAG38114.1 - 0.23 10.4 0.0 0.38 9.7 0.0 1.2 1 0 0 1 1 1 0 Siphovirus ReqiPepy6 Gp37-like protein CAP59_mtransfer PF11735.8 OAG38115.1 - 1.6e-73 247.4 0.0 2.1e-73 247.0 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 CENP-B_dimeris PF09026.10 OAG38116.1 - 6.9 7.1 9.6 1.2 9.6 2.5 2.6 2 0 0 2 2 2 0 Centromere protein B dimerisation domain SSF PF00474.17 OAG38117.1 - 1.1e-07 31.1 26.0 5e-07 28.9 26.0 2.0 1 1 0 1 1 1 1 Sodium:solute symporter family Flavin_Reduct PF01613.18 OAG38118.1 - 9.1e-16 58.3 0.0 1.3e-15 57.8 0.0 1.2 1 0 0 1 1 1 1 Flavin reductase like domain Dmrt1 PF12374.8 OAG38118.1 - 0.077 13.4 0.5 1.3 9.6 0.1 2.6 2 1 0 2 2 2 0 Double-sex mab3 related transcription factor 1 Abhydrolase_1 PF00561.20 OAG38119.1 - 3.4e-14 53.1 0.1 2.8e-13 50.1 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAG38119.1 - 0.00017 20.9 0.0 0.0036 16.6 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Muraidase PF11860.8 OAG38119.1 - 0.0059 16.9 0.0 0.03 14.6 0.0 2.0 1 1 0 1 1 1 1 N-acetylmuramidase Esterase PF00756.20 OAG38119.1 - 0.026 14.2 0.1 0.063 12.9 0.1 1.6 1 1 0 1 1 1 0 Putative esterase Abhydrolase_6 PF12697.7 OAG38119.1 - 0.034 14.8 0.0 0.047 14.3 0.0 1.3 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF1349 PF07081.11 OAG38120.1 - 5.5e-27 94.6 0.0 6.8e-27 94.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) HEAT PF02985.22 OAG38121.1 - 9.5e-08 31.7 0.4 0.098 13.0 0.0 5.6 5 0 0 5 5 5 2 HEAT repeat HEAT_EZ PF13513.6 OAG38121.1 - 0.00035 21.0 0.6 0.33 11.5 0.1 4.0 3 0 0 3 3 3 1 HEAT-like repeat HEAT_2 PF13646.6 OAG38121.1 - 0.0035 17.7 1.8 0.15 12.5 0.1 4.3 4 1 0 4 4 4 1 HEAT repeats Adaptin_N PF01602.20 OAG38121.1 - 0.04 12.5 0.0 1.2 7.6 0.0 2.9 3 0 0 3 3 3 0 Adaptin N terminal region PXA PF02194.15 OAG38121.1 - 0.15 12.0 0.3 34 4.3 0.0 4.0 4 0 0 4 4 4 0 PXA domain Polyketide_cyc2 PF10604.9 OAG38122.1 - 2.7e-12 47.2 1.0 3.5e-12 46.8 1.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 OAG38122.1 - 1e-05 25.7 0.5 1.4e-05 25.3 0.5 1.3 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Piwi PF02171.17 OAG38123.1 - 2.1e-49 168.4 0.0 3.1e-49 167.8 0.0 1.3 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 OAG38123.1 - 1.2e-09 38.9 0.1 7.5e-09 36.3 0.1 2.2 2 0 0 2 2 2 1 N-terminal domain of argonaute ArgoMid PF16487.5 OAG38123.1 - 0.00062 20.0 0.8 0.0019 18.4 0.2 2.1 2 0 0 2 2 2 1 Mid domain of argonaute ArgoL1 PF08699.10 OAG38123.1 - 0.012 15.3 0.0 0.078 12.7 0.0 2.4 3 0 0 3 3 3 0 Argonaute linker 1 domain ArgoL2 PF16488.5 OAG38123.1 - 0.014 15.7 0.0 0.052 13.9 0.0 2.1 1 0 0 1 1 1 0 Argonaute linker 2 domain OxoGdeHyase_C PF16870.5 OAG38123.1 - 0.078 12.7 0.2 0.15 11.8 0.2 1.3 1 0 0 1 1 1 0 2-oxoglutarate dehydrogenase C-terminal NRDE-2 PF08424.10 OAG38124.1 - 1.2e-84 284.3 0.1 1.2e-84 284.3 0.1 3.2 3 0 0 3 3 3 1 NRDE-2, necessary for RNA interference BP28CT PF08146.12 OAG38124.1 - 2.7e-32 111.8 0.3 1.3e-31 109.6 0.1 2.4 2 0 0 2 2 2 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.8 OAG38124.1 - 1e-13 51.6 0.2 1e-13 51.6 0.2 4.8 5 0 0 5 5 5 1 U3 small nucleolar RNA-associated protein 10 HEAT PF02985.22 OAG38124.1 - 7.6e-05 22.6 6.5 0.053 13.8 0.1 5.7 5 0 0 5 5 4 1 HEAT repeat TPR_14 PF13428.6 OAG38124.1 - 0.00093 19.8 8.6 0.25 12.3 1.7 6.3 4 1 1 5 5 5 1 Tetratricopeptide repeat HEAT_EZ PF13513.6 OAG38124.1 - 0.02 15.4 0.4 0.02 15.4 0.4 5.2 6 0 0 6 6 6 0 HEAT-like repeat DUF2967 PF11179.8 OAG38124.1 - 0.024 12.8 0.0 0.041 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) TPR_2 PF07719.17 OAG38124.1 - 0.071 13.3 2.2 2.6 8.4 0.4 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 OAG38124.1 - 0.22 12.1 4.9 5.3 7.6 0.1 4.5 3 0 0 3 3 3 0 Tetratricopeptide repeat HEAT_2 PF13646.6 OAG38124.1 - 6.1 7.3 16.0 0.58 10.6 0.2 5.2 6 0 0 6 6 5 0 HEAT repeats TPR_16 PF13432.6 OAG38124.1 - 9.6 7.0 6.4 3.4 8.4 1.4 3.0 3 1 0 3 3 3 0 Tetratricopeptide repeat Fungal_trans PF04082.18 OAG38125.1 - 4.2e-08 32.6 0.1 6.6e-08 31.9 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG38125.1 - 6.2e-05 23.0 10.2 0.00012 22.1 10.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.22 OAG38127.1 - 6.4e-46 157.1 0.0 1e-44 153.1 0.0 2.1 1 1 0 1 1 1 1 Cytochrome P450 HSP20 PF00011.21 OAG38128.1 - 3e-09 36.9 0.2 6.5e-09 35.9 0.2 1.6 1 0 0 1 1 1 1 Hsp20/alpha crystallin family DUF2981 PF11200.8 OAG38128.1 - 2 8.1 4.1 3.7 7.2 4.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) Glyco_tranf_2_3 PF13641.6 OAG38129.1 - 5.5e-33 114.8 0.1 7.7e-33 114.3 0.1 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 OAG38129.1 - 2.9e-11 43.5 0.0 5.1e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 OAG38129.1 - 8.6e-10 38.4 0.0 5.3e-09 35.8 0.0 2.1 1 1 0 1 1 1 1 Glycosyl transferase family 21 Ion_trans_2 PF07885.16 OAG38130.1 - 6.5e-30 102.9 21.7 2.3e-17 62.7 3.9 3.2 3 0 0 3 3 3 2 Ion channel DUF2198 PF09964.9 OAG38130.1 - 0.028 14.5 0.4 1.4 9.1 0.0 2.8 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2198) VWA_CoxE PF05762.14 OAG38130.1 - 0.11 11.9 0.2 0.2 11.0 0.2 1.3 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein Ion_trans PF00520.31 OAG38130.1 - 0.82 8.8 14.6 0.21 10.8 3.4 2.8 2 1 1 3 3 3 0 Ion transport protein DUF2207 PF09972.9 OAG38130.1 - 1.3 7.7 3.5 0.89 8.2 0.0 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Mst1_SARAH PF11629.8 OAG38131.1 - 0.041 14.0 0.0 0.099 12.7 0.0 1.6 1 0 0 1 1 1 0 C terminal SARAH domain of Mst1 RCC_reductase PF06405.11 OAG38131.1 - 0.15 11.2 0.0 0.3 10.2 0.0 1.4 1 0 0 1 1 1 0 Red chlorophyll catabolite reductase (RCC reductase) Stc1 PF12898.7 OAG38132.1 - 8.9e-16 58.2 5.2 2.3e-15 56.9 5.2 1.7 1 0 0 1 1 1 1 Stc1 domain RAP1 PF07218.11 OAG38132.1 - 9.7 4.3 6.4 11 4.2 6.4 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Pkinase PF00069.25 OAG38133.1 - 4.7e-57 193.4 0.0 7e-57 192.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG38133.1 - 1.1e-30 106.8 0.0 5.4e-29 101.3 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OAG38133.1 - 0.0023 17.0 0.0 0.0039 16.2 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Pox_ser-thr_kin PF05445.11 OAG38133.1 - 0.034 13.1 0.0 0.052 12.5 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF3275 PF11679.8 OAG38133.1 - 0.25 11.3 1.0 0.75 9.7 1.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) Siah-Interact_N PF09032.11 OAG38134.1 - 4.9 7.5 7.6 0.7 10.2 1.1 2.7 3 0 0 3 3 3 0 Siah interacting protein, N terminal GTP_cyclohydro2 PF00925.20 OAG38135.1 - 3.7e-57 192.5 0.0 5.6e-52 175.6 0.0 2.1 2 0 0 2 2 2 2 GTP cyclohydrolase II DUF1325 PF07039.11 OAG38137.1 - 1.3e-19 70.6 2.2 2.1e-19 69.9 2.2 1.3 1 0 0 1 1 1 1 SGF29 tudor-like domain LBR_tudor PF09465.10 OAG38137.1 - 0.039 13.8 0.1 0.12 12.2 0.1 1.9 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain zf-C4H2 PF10146.9 OAG38137.1 - 0.044 14.1 1.5 0.086 13.1 1.5 1.6 1 1 0 1 1 1 0 Zinc finger-containing protein 53-BP1_Tudor PF09038.10 OAG38137.1 - 0.088 12.8 0.1 0.45 10.5 0.0 2.1 2 0 0 2 2 2 0 Tumour suppressor p53-binding protein-1 Tudor CAP18_C PF12153.8 OAG38137.1 - 0.092 12.6 0.2 0.17 11.7 0.2 1.4 1 0 0 1 1 1 0 LPS binding domain of CAP18 (C terminal) PMI_typeI PF01238.21 OAG38138.1 - 1e-136 456.0 0.0 1.2e-136 455.8 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I p450 PF00067.22 OAG38139.1 - 5.1e-23 81.5 0.1 4.1e-22 78.6 0.1 1.9 1 1 0 1 1 1 1 Cytochrome P450 GFO_IDH_MocA PF01408.22 OAG38140.1 - 3.1e-21 76.4 0.0 5.4e-21 75.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 OAG38140.1 - 0.0015 18.5 0.0 0.0028 17.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 OAG38140.1 - 0.0032 18.1 0.3 0.0081 16.8 0.3 1.6 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Cytochrom_C PF00034.21 OAG38141.1 - 1e-10 42.6 0.2 5.5e-10 40.3 0.0 1.9 2 0 0 2 2 2 1 Cytochrome c Cytochrome_CBB3 PF13442.6 OAG38141.1 - 3.2e-07 30.6 0.4 1.9e-06 28.1 0.4 2.0 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 OAG38141.1 - 0.0011 18.7 0.2 0.0048 16.6 0.2 1.9 2 0 0 2 2 2 1 Cytochrome c-550 domain Cytochrome-c551 PF10643.9 OAG38141.1 - 0.13 11.8 0.0 0.16 11.5 0.0 1.1 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 SHE3 PF17078.5 OAG38142.1 - 0.099 12.3 0.9 1 9.0 0.1 2.4 2 1 1 3 3 3 0 SWI5-dependent HO expression protein 3 CRM1_C PF08767.11 OAG38142.1 - 0.12 11.5 0.7 2.4 7.2 0.1 2.1 2 0 0 2 2 2 0 CRM1 C terminal RNase_PH PF01138.21 OAG38143.1 - 1.3e-15 58.1 0.0 4e-15 56.5 0.0 1.8 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 OAG38143.1 - 0.0011 19.0 0.1 0.0021 18.1 0.1 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 DJ-1_PfpI PF01965.24 OAG38144.1 - 7.4e-14 51.9 0.0 1.3e-13 51.1 0.0 1.4 1 1 0 1 1 1 1 DJ-1/PfpI family IDO PF01231.18 OAG38145.1 - 1.3e-99 334.0 0.0 1.9e-98 330.1 0.0 2.1 1 1 0 1 1 1 1 Indoleamine 2,3-dioxygenase Trp_dioxygenase PF03301.13 OAG38145.1 - 0.0094 15.3 0.2 2.5 7.3 0.0 3.1 2 1 1 3 3 3 2 Tryptophan 2,3-dioxygenase Spermine_synth PF01564.17 OAG38147.1 - 9.1e-71 237.2 0.0 1.5e-70 236.5 0.0 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 OAG38147.1 - 6.6e-24 83.6 0.1 1.1e-23 82.8 0.1 1.4 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 OAG38147.1 - 0.00078 20.1 0.0 0.0014 19.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG38147.1 - 0.027 15.2 0.4 0.12 13.1 0.0 2.3 3 0 0 3 3 3 0 Methyltransferase domain Methyltransf_18 PF12847.7 OAG38147.1 - 0.027 14.4 0.0 0.049 13.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DUF43 PF01861.16 OAG38147.1 - 0.044 13.0 0.0 0.068 12.4 0.0 1.2 1 0 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain Myb_DNA-binding PF00249.31 OAG38147.1 - 0.15 12.3 0.1 0.4 10.9 0.1 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain TRI12 PF06609.13 OAG38148.1 - 2.3e-39 135.3 17.1 2.8e-39 135.0 17.1 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG38148.1 - 1.5e-24 86.6 44.2 1.5e-24 86.6 44.2 2.4 2 2 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG38148.1 - 4.5e-08 32.4 10.0 4.5e-08 32.4 10.0 3.3 3 1 1 4 4 4 1 Sugar (and other) transporter Phage_holin_3_5 PF16085.5 OAG38148.1 - 0.088 13.0 6.6 1.4 9.1 0.0 3.3 3 0 0 3 3 3 0 Bacteriophage holin Hol, superfamily III p450 PF00067.22 OAG38149.1 - 7.5e-66 222.8 0.0 9e-66 222.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Molybdopterin PF00384.22 OAG38149.1 - 0.086 11.8 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Molybdopterin oxidoreductase QSregVF_b PF12843.7 OAG38149.1 - 0.11 12.4 0.1 0.32 10.9 0.1 1.7 1 0 0 1 1 1 0 Putative quorum-sensing-regulated virulence factor Mus7 PF09462.10 OAG38151.1 - 2.3e-25 89.5 2.4 5.5e-23 81.7 2.4 2.2 1 1 0 1 1 1 1 Mus7/MMS22 family PAPA-1 PF04795.12 OAG38152.1 - 2.3e-21 76.4 3.2 2.3e-21 76.4 3.2 3.6 3 1 0 3 3 3 1 PAPA-1-like conserved region RNA_pol_3_Rpc31 PF11705.8 OAG38152.1 - 0.0077 16.5 6.3 0.0077 16.5 6.3 4.2 4 1 0 4 4 4 1 DNA-directed RNA polymerase III subunit Rpc31 Pex14_N PF04695.13 OAG38153.1 - 2.8e-38 132.0 3.6 2.8e-38 132.0 3.6 3.4 3 1 1 4 4 4 1 Peroxisomal membrane anchor protein (Pex14p) conserved region SRA1 PF07304.11 OAG38154.1 - 6.3e-09 35.8 0.0 6.3e-09 35.8 0.0 4.0 4 1 0 4 4 4 1 Steroid receptor RNA activator (SRA1) Sec16_C PF12931.7 OAG38154.1 - 0.0029 17.3 0.2 0.028 14.1 0.2 2.3 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 Prp18 PF02840.15 OAG38154.1 - 0.0035 17.4 0.0 0.0084 16.2 0.0 1.6 1 0 0 1 1 1 1 Prp18 domain WD40 PF00400.32 OAG38154.1 - 0.011 16.6 10.3 0.013 16.3 0.2 5.0 6 0 0 6 6 6 0 WD domain, G-beta repeat RRM_1 PF00076.22 OAG38155.1 - 5.3e-16 58.2 0.0 8e-16 57.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OAG38155.1 - 0.0016 18.0 0.0 0.0043 16.6 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 OAG38155.1 - 0.063 13.3 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif NUDIX PF00293.28 OAG38156.1 - 1.1e-18 67.6 0.5 1.3e-18 67.3 0.5 1.1 1 0 0 1 1 1 1 NUDIX domain DUF4913 PF16259.5 OAG38156.1 - 0.014 15.5 1.3 3.8 7.6 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4913) ATE_C PF04377.15 OAG38157.1 - 3.7e-47 160.3 2.3 5.8e-47 159.7 2.3 1.3 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus Acetyltransf_6 PF13480.7 OAG38157.1 - 0.043 14.0 0.8 0.085 13.0 0.8 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain GrpE PF01025.19 OAG38158.1 - 1.3e-41 142.0 2.5 2.4e-41 141.2 2.5 1.4 1 1 0 1 1 1 1 GrpE Syntaxin PF00804.25 OAG38158.1 - 0.0098 15.6 1.1 0.014 15.0 1.1 1.2 1 0 0 1 1 1 1 Syntaxin ALMS_motif PF15309.6 OAG38158.1 - 0.015 15.8 1.8 0.015 15.8 1.8 1.6 2 0 0 2 2 2 0 ALMS motif CCD48 PF15799.5 OAG38158.1 - 0.045 12.1 3.0 0.059 11.7 3.0 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 48 WDCP PF15390.6 OAG38158.1 - 0.34 9.3 1.1 0.45 8.8 1.1 1.2 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family tRNA-synt_2d PF01409.20 OAG38159.1 - 3.6e-48 164.2 0.0 3.6e-26 92.1 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 OAG38159.1 - 1.3e-25 89.6 0.0 4.9e-25 87.8 0.0 2.0 1 1 0 1 1 1 1 Ferredoxin-fold anticodon binding domain Mito_carr PF00153.27 OAG38160.1 - 3.4e-55 184.0 1.5 1.3e-19 69.9 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Calcipressin PF04847.12 OAG38161.1 - 4.2e-36 124.4 0.2 1.2e-35 123.0 0.2 1.7 1 1 0 1 1 1 1 Calcipressin FMO-like PF00743.19 OAG38162.1 - 1.9e-20 72.8 0.2 3.2e-18 65.5 0.1 2.5 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 OAG38162.1 - 3.1e-10 39.8 0.0 1e-06 28.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG38162.1 - 1.8e-09 37.2 0.0 2.2e-05 23.8 0.0 3.2 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 OAG38162.1 - 1.5e-07 31.6 0.0 3.6e-07 30.3 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 OAG38162.1 - 3.8e-05 23.1 0.0 0.0011 18.3 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAG38162.1 - 0.024 14.6 0.0 0.36 10.8 0.0 2.5 3 0 0 3 3 3 0 FAD-NAD(P)-binding Shikimate_DH PF01488.20 OAG38162.1 - 0.034 14.2 0.0 4.4 7.4 0.0 3.1 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase PS_pyruv_trans PF04230.13 OAG38162.1 - 0.038 13.9 0.3 0.13 12.2 0.1 2.0 1 1 1 2 2 2 0 Polysaccharide pyruvyl transferase Flavodoxin_1 PF00258.25 OAG38162.1 - 0.04 14.1 0.0 0.87 9.8 0.0 2.4 2 0 0 2 2 2 0 Flavodoxin Cupin_2 PF07883.11 OAG38163.1 - 6.2e-16 57.9 0.0 9.8e-16 57.2 0.0 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 OAG38163.1 - 5.8e-06 26.2 0.0 8.7e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.22 OAG38163.1 - 8.1e-05 22.3 0.0 0.00012 21.8 0.0 1.2 1 0 0 1 1 1 1 Cupin ARD PF03079.14 OAG38163.1 - 0.00024 21.3 0.7 0.00044 20.5 0.0 1.7 2 0 0 2 2 2 1 ARD/ARD' family Cupin_3 PF05899.12 OAG38163.1 - 0.0069 16.1 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF861) JmjC PF02373.22 OAG38163.1 - 0.025 15.0 0.0 0.041 14.3 0.0 1.3 1 0 0 1 1 1 0 JmjC domain, hydroxylase Cupin_6 PF12852.7 OAG38163.1 - 0.034 13.9 0.0 0.039 13.7 0.0 1.1 1 0 0 1 1 1 0 Cupin GPI PF06560.11 OAG38163.1 - 0.054 12.8 0.0 0.089 12.1 0.0 1.4 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) EutQ PF06249.12 OAG38163.1 - 0.082 12.7 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutQ WGG PF10273.9 OAG38164.1 - 4.1e-24 85.0 0.4 8.4e-24 84.0 0.4 1.5 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 Nop25 PF09805.9 OAG38164.1 - 0.12 12.8 2.7 0.18 12.2 2.7 1.3 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) SDA1 PF05285.12 OAG38164.1 - 0.21 11.0 8.4 0.25 10.7 8.4 1.1 1 0 0 1 1 1 0 SDA1 adh_short_C2 PF13561.6 OAG38165.1 - 7.9e-52 176.1 1.5 1.1e-51 175.7 1.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG38165.1 - 2.8e-40 137.9 1.5 3.6e-40 137.5 1.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG38165.1 - 9.8e-13 48.4 1.0 1.3e-12 48.0 1.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG38165.1 - 0.00058 19.4 0.2 0.00087 18.8 0.2 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAG38165.1 - 0.054 12.9 0.0 0.5 9.7 0.0 2.0 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase ELFV_dehydrog PF00208.21 OAG38165.1 - 0.085 12.6 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Ammonium_transp PF00909.21 OAG38166.1 - 2.6e-109 365.5 26.7 3e-109 365.3 26.7 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Gln-synt_C PF00120.24 OAG38167.1 - 2.4e-16 59.7 0.0 1.4e-12 47.3 0.0 2.2 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 OAG38167.1 - 7.5e-14 51.2 0.0 1.5e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Glyco_transf_28 PF03033.20 OAG38168.1 - 4.9e-15 55.8 0.0 1.3e-14 54.5 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 OAG38168.1 - 1.8e-05 23.7 0.0 3.5e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 OAG38168.1 - 0.00011 22.3 0.0 0.00024 21.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain ATG_C PF09333.11 OAG38168.1 - 0.001 19.4 0.0 0.006 16.9 0.0 2.3 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain HECT PF00632.25 OAG38171.1 - 1.1e-76 258.3 0.0 1.8e-76 257.6 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Arm PF00514.23 OAG38171.1 - 0.015 15.3 11.0 15 5.8 0.0 6.7 8 0 0 8 8 8 0 Armadillo/beta-catenin-like repeat CTP_transf_like PF01467.26 OAG38172.1 - 3.9e-26 92.0 0.0 5.2e-26 91.6 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase-like Ubie_methyltran PF01209.18 OAG38174.1 - 1.4e-75 253.6 0.0 1.6e-75 253.4 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 OAG38174.1 - 5.3e-17 62.3 0.0 9.7e-17 61.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG38174.1 - 1.4e-14 54.2 0.0 1.6e-14 53.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG38174.1 - 9.2e-14 51.9 0.0 1.9e-13 50.9 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG38174.1 - 2.7e-07 31.2 0.0 3.9e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAG38174.1 - 3e-07 30.4 0.0 3.9e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 OAG38174.1 - 0.0038 17.2 0.0 0.0046 17.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 OAG38174.1 - 0.15 11.9 0.0 0.64 9.8 0.0 2.0 3 0 0 3 3 3 0 Hypothetical methyltransferase E1_dh PF00676.20 OAG38175.1 - 4.2e-90 301.7 0.0 5.1e-90 301.4 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component Glyco_hydro_16 PF00722.21 OAG38176.1 - 6.2e-43 146.3 4.7 1e-42 145.6 4.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 zf-C2H2_2 PF12756.7 OAG38178.1 - 8.1e-36 122.4 15.5 1.5e-29 102.3 3.2 3.5 2 1 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 OAG38178.1 - 5e-11 42.6 17.2 1e-07 32.0 1.3 4.3 4 1 1 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OAG38178.1 - 8.4e-07 29.2 3.0 8.4e-07 29.2 3.0 3.2 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 OAG38178.1 - 0.0056 17.4 13.3 3.7 8.6 0.1 5.2 5 0 0 5 5 5 2 C2H2-type zinc finger zf-C2H2 PF00096.26 OAG38178.1 - 0.068 13.7 18.5 0.33 11.5 0.3 4.8 4 1 1 5 5 5 0 Zinc finger, C2H2 type Mso1_Sec1_bdg PF14475.6 OAG38178.1 - 0.12 12.0 1.1 0.47 10.1 0.7 2.3 2 0 0 2 2 2 0 Sec1-binding region of Mso1 Cytochrome_CBB3 PF13442.6 OAG38178.1 - 1.8 9.0 4.9 26 5.2 0.8 3.0 2 0 0 2 2 2 0 Cytochrome C oxidase, cbb3-type, subunit III TTRAP PF14203.6 OAG38179.1 - 0.5 10.4 8.9 0.18 11.8 0.9 3.7 3 0 0 3 3 3 0 Putative tranposon-transfer assisting protein SKG6 PF08693.10 OAG38180.1 - 0.0028 17.0 4.3 0.007 15.8 4.3 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Insulin_TMD PF17870.1 OAG38180.1 - 0.014 15.5 0.4 0.024 14.7 0.4 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment LapA_dom PF06305.11 OAG38180.1 - 0.014 15.2 1.2 0.024 14.4 1.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain SPP PF06550.11 OAG38180.1 - 0.02 14.3 0.2 0.028 13.9 0.2 1.1 1 0 0 1 1 1 0 Signal-peptide peptidase, presenilin aspartyl protease TMEM154 PF15102.6 OAG38180.1 - 0.11 12.4 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 TMEM154 protein family Amnionless PF14828.6 OAG38180.1 - 0.12 11.1 0.0 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 Amnionless COX6C PF02937.15 OAG38180.1 - 0.16 12.2 0.3 0.29 11.3 0.3 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIc zf-UBR PF02207.20 OAG38181.1 - 1.4e-18 66.8 12.8 4.5e-18 65.2 12.8 2.0 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 OAG38181.1 - 0.0014 18.4 0.1 0.0079 16.0 0.0 2.2 2 0 0 2 2 2 1 ATP-dependent Clp protease adaptor protein ClpS zf-RING_2 PF13639.6 OAG38181.1 - 0.019 15.3 1.0 0.019 15.3 1.0 3.8 3 1 0 3 3 3 0 Ring finger domain Acetyltransf_11 PF13720.6 OAG38181.1 - 0.15 12.6 0.2 0.84 10.1 0.0 2.4 2 0 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Rhabdo_ncap PF00945.18 OAG38181.1 - 1.8 7.4 3.3 12 4.6 0.0 2.3 2 0 0 2 2 2 0 Rhabdovirus nucleocapsid protein RPAP1_C PF08620.10 OAG38182.1 - 0.0016 18.5 0.9 0.0016 18.5 0.9 3.4 2 2 1 3 3 3 1 RPAP1-like, C-terminal UCR_UQCRX_QCR9 PF05365.12 OAG38183.1 - 1.3e-24 85.8 2.3 1.7e-24 85.5 2.3 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Mago-bind PF09282.10 OAG38185.1 - 8.4e-14 51.1 3.6 1.6e-13 50.3 3.6 1.5 1 0 0 1 1 1 1 Mago binding Flagellin_N PF00669.20 OAG38185.1 - 0.34 11.0 5.2 0.51 10.4 5.2 1.2 1 0 0 1 1 1 0 Bacterial flagellin N-terminal helical region Amino_oxidase PF01593.24 OAG38186.1 - 3.6e-10 39.7 0.4 2.2e-09 37.1 0.4 1.9 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 OAG38186.1 - 0.11 11.7 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAG38186.1 - 0.2 12.2 0.1 0.54 10.9 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Chitin_synth_2 PF03142.15 OAG38187.1 - 6.6e-289 958.9 0.2 1.2e-288 958.0 0.0 1.5 2 0 0 2 2 2 1 Chitin synthase Glyco_trans_2_3 PF13632.6 OAG38187.1 - 1.9e-12 47.5 4.4 1.2e-11 44.9 4.4 2.4 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 OAG38187.1 - 3e-11 43.6 0.0 1e-08 35.4 0.0 2.5 2 1 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 OAG38187.1 - 0.00023 20.7 0.1 0.0031 17.0 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 OAG38187.1 - 0.0054 16.6 0.0 0.084 12.7 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 2 Sel1 PF08238.12 OAG38188.1 - 6.8e-37 125.1 29.0 6e-06 26.8 0.1 7.4 7 0 0 7 7 7 7 Sel1 repeat MFS_1 PF07690.16 OAG38189.1 - 1e-38 133.2 26.6 1e-38 133.2 26.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG38189.1 - 9.5e-09 34.6 26.2 1.4e-08 34.1 26.2 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_4 PF06779.14 OAG38189.1 - 0.0001 21.7 2.6 0.0001 21.7 2.6 2.2 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB GTA_TIM PF13547.6 OAG38191.1 - 0.064 12.5 0.0 0.09 12.0 0.0 1.2 1 0 0 1 1 1 0 GTA TIM-barrel-like domain Dexa_ind PF15198.6 OAG38191.1 - 0.084 13.0 0.1 0.18 11.9 0.1 1.5 1 0 0 1 1 1 0 Dexamethasone-induced AnmK PF03702.14 OAG38192.1 - 3.5e-71 240.3 0.0 2.2e-68 231.1 0.0 2.0 1 1 0 1 1 1 1 Anhydro-N-acetylmuramic acid kinase Ank_5 PF13857.6 OAG38192.1 - 0.011 16.1 0.1 1.5 9.2 0.0 3.0 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Sugar_tr PF00083.24 OAG38193.1 - 1.3e-79 268.2 30.8 1.6e-79 267.9 30.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG38193.1 - 1.3e-18 67.1 24.5 1.3e-18 67.1 24.5 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Aldo_ket_red PF00248.21 OAG38194.1 - 1.2e-69 234.7 0.0 1.4e-69 234.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family RHH_1 PF01402.21 OAG38194.1 - 0.54 10.3 2.3 1.2 9.2 0.0 2.6 3 0 0 3 3 3 0 Ribbon-helix-helix protein, copG family Amidase PF01425.21 OAG38195.1 - 1.7e-88 297.6 0.0 2.1e-88 297.3 0.0 1.1 1 0 0 1 1 1 1 Amidase Polysacc_deac_1 PF01522.21 OAG38196.1 - 3e-13 49.7 0.0 5.5e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Fungal_trans PF04082.18 OAG38197.1 - 2.4e-26 92.4 0.1 3.6e-26 91.8 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG38197.1 - 9.8e-09 35.2 7.9 2.1e-08 34.1 7.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 OAG38197.1 - 0.027 13.3 1.2 0.13 11.1 1.2 1.9 1 1 0 1 1 1 0 Fungal specific transcription factor domain Dicer_N PF17895.1 OAG38197.1 - 0.14 12.0 0.0 1.6 8.5 0.0 2.4 2 0 0 2 2 2 0 Giardia Dicer N-terminal domain Transp_cyt_pur PF02133.15 OAG38198.1 - 1.6e-92 310.6 36.8 1.9e-92 310.3 36.8 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin MFS_1 PF07690.16 OAG38199.1 - 8.5e-42 143.3 44.3 3.1e-41 141.5 43.2 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 OAG38199.1 - 1.2e-16 60.3 17.3 4.5e-16 58.4 17.3 1.8 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 OAG38199.1 - 2.5e-15 56.3 3.3 2.5e-15 56.3 3.3 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter YlaH PF14036.6 OAG38199.1 - 0.065 13.6 0.8 0.25 11.7 0.1 2.3 2 0 0 2 2 2 0 YlaH-like protein AA_permease_2 PF13520.6 OAG38200.1 - 4.6e-67 226.7 44.4 6e-67 226.3 44.4 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAG38200.1 - 1.1e-16 60.5 42.4 1.4e-16 60.2 42.4 1.0 1 0 0 1 1 1 1 Amino acid permease OTT_1508_deam PF14441.6 OAG38201.1 - 9.8e-20 70.3 0.1 2e-19 69.4 0.1 1.5 1 0 0 1 1 1 1 OTT_1508-like deaminase Opiods_neuropep PF01160.18 OAG38201.1 - 0.17 12.0 1.1 0.54 10.4 1.1 1.9 1 0 0 1 1 1 0 Vertebrate endogenous opioids neuropeptide AA_permease_2 PF13520.6 OAG38202.1 - 8.9e-40 136.8 52.5 9.6e-21 74.1 27.3 2.0 1 1 1 2 2 2 2 Amino acid permease AA_permease PF00324.21 OAG38202.1 - 7.7e-15 54.4 48.2 5.8e-08 31.8 18.1 2.1 1 1 1 2 2 2 2 Amino acid permease Colicin_V PF02674.16 OAG38202.1 - 0.7 9.9 34.1 0.17 11.9 5.0 4.3 3 1 1 4 4 4 0 Colicin V production protein WXG100 PF06013.12 OAG38204.1 - 0.014 15.6 1.4 1.2 9.4 0.0 2.8 3 0 0 3 3 3 0 Proteins of 100 residues with WXG Exonuc_VII_L PF02601.15 OAG38204.1 - 0.28 10.7 2.3 0.43 10.1 2.3 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit KLRAQ PF10205.9 OAG38204.1 - 0.45 10.8 4.9 0.96 9.7 4.9 1.6 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein Csm1_N PF18504.1 OAG38204.1 - 0.46 10.9 6.8 0.14 12.5 1.3 2.9 2 1 1 3 3 3 0 Csm1 N-terminal domain PKcGMP_CC PF16808.5 OAG38204.1 - 0.96 9.4 8.6 1.8 8.5 5.6 2.4 1 1 1 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Acyltransferase PF01553.21 OAG38205.1 - 3.1e-09 36.6 0.0 0.0023 17.6 0.0 2.3 2 0 0 2 2 2 2 Acyltransferase End_N_terminal PF12218.8 OAG38205.1 - 0.15 11.7 0.0 0.34 10.6 0.0 1.5 1 0 0 1 1 1 0 N terminal extension of bacteriophage endosialidase WD40 PF00400.32 OAG38206.1 - 1.4e-30 104.8 14.3 5.6e-05 23.8 0.0 7.8 8 0 0 8 8 8 5 WD domain, G-beta repeat F-box-like PF12937.7 OAG38206.1 - 5.2e-13 48.7 0.1 9.8e-13 47.8 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAG38206.1 - 1.1e-07 31.5 0.0 2.5e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 F-box domain ANAPC4_WD40 PF12894.7 OAG38206.1 - 3.3e-07 30.5 0.1 0.15 12.4 0.0 4.1 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OAG38206.1 - 0.00076 18.2 1.4 1.2 7.7 0.6 3.0 2 1 1 3 3 3 2 Nucleoporin Nup120/160 MgtE_N PF03448.17 OAG38206.1 - 0.019 15.5 0.1 0.048 14.3 0.1 1.6 1 0 0 1 1 1 0 MgtE intracellular N domain F-box_4 PF15966.5 OAG38206.1 - 0.033 14.1 0.0 0.078 12.9 0.0 1.6 1 0 0 1 1 1 0 F-box PALB2_WD40 PF16756.5 OAG38206.1 - 0.13 11.2 0.0 8.9 5.1 0.0 2.3 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain Prenyltransf PF01255.19 OAG38207.1 - 3.1e-83 278.7 0.7 1.1e-82 276.9 0.7 1.7 1 1 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Peptidase_M41 PF01434.18 OAG38209.1 - 3.3e-55 186.9 0.2 5.6e-55 186.1 0.2 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 OAG38209.1 - 3.9e-43 147.0 0.0 1.2e-42 145.5 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OAG38209.1 - 1e-10 41.3 0.1 2.8e-10 39.8 0.1 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 OAG38209.1 - 4.1e-06 26.8 0.0 1.3e-05 25.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OAG38209.1 - 1.8e-05 25.2 0.1 0.00011 22.6 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OAG38209.1 - 0.00013 22.3 0.0 0.011 16.1 0.0 2.8 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 OAG38209.1 - 0.00014 21.6 0.0 0.0003 20.5 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 OAG38209.1 - 0.00029 20.1 0.0 0.0007 18.9 0.0 1.6 2 0 0 2 2 2 1 TIP49 P-loop domain DUF815 PF05673.13 OAG38209.1 - 0.0012 18.1 0.0 0.003 16.8 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 OAG38209.1 - 0.0017 18.1 0.0 0.0032 17.2 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.6 OAG38209.1 - 0.0032 17.6 0.0 0.0071 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 OAG38209.1 - 0.0037 16.7 0.3 0.0081 15.6 0.3 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI FumaraseC_C PF10415.9 OAG38209.1 - 0.01 16.3 1.1 0.028 14.8 1.1 1.8 1 0 0 1 1 1 0 Fumarase C C-terminus AAA_18 PF13238.6 OAG38209.1 - 0.023 15.2 0.1 0.098 13.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 OAG38209.1 - 0.024 14.6 0.1 0.18 11.7 0.1 2.2 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.6 OAG38209.1 - 0.026 14.7 1.1 0.047 13.9 0.0 2.0 2 0 0 2 2 1 0 AAA domain AAA_14 PF13173.6 OAG38209.1 - 0.028 14.5 0.0 0.085 12.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 OAG38209.1 - 0.038 13.6 0.3 0.54 9.8 0.1 2.4 1 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 OAG38209.1 - 0.048 12.9 2.0 0.24 10.7 0.6 2.3 1 1 1 2 2 2 0 Zeta toxin TniB PF05621.11 OAG38209.1 - 0.081 12.3 0.0 0.24 10.8 0.0 1.8 1 0 0 1 1 1 0 Bacterial TniB protein TsaE PF02367.17 OAG38209.1 - 0.092 12.8 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 OAG38209.1 - 0.094 12.2 0.1 0.26 10.8 0.1 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_30 PF13604.6 OAG38209.1 - 0.1 12.3 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain FliG_N PF14842.6 OAG38209.1 - 0.59 10.7 3.3 1.3 9.6 3.3 1.6 1 0 0 1 1 1 0 FliG N-terminal domain DUF3552 PF12072.8 OAG38209.1 - 0.74 9.2 9.2 0.09 12.2 3.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) DUF4448 PF14610.6 OAG38210.1 - 0.065 13.0 0.1 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DUF4381 PF14316.6 OAG38210.1 - 0.09 13.0 0.1 0.15 12.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Peptidase_M56 PF05569.11 OAG38210.1 - 0.16 11.2 0.0 0.24 10.6 0.0 1.2 1 0 0 1 1 1 0 BlaR1 peptidase M56 SKG6 PF08693.10 OAG38210.1 - 0.3 10.5 5.9 0.73 9.3 5.9 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF1223 PF06764.11 OAG38211.1 - 7.2e-50 169.8 0.0 8.6e-50 169.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1223) Pkinase PF00069.25 OAG38212.1 - 8.2e-24 84.4 0.0 1.6e-23 83.5 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG38212.1 - 0.00014 21.3 0.0 0.00037 19.9 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OAG38212.1 - 0.039 13.9 0.4 0.82 9.5 0.1 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family K_trans PF02705.16 OAG38213.1 - 1.1e-169 565.4 8.5 4.4e-162 540.3 2.5 2.0 1 1 1 2 2 2 2 K+ potassium transporter Na_H_Exchanger PF00999.21 OAG38214.1 - 2.5e-39 135.2 29.0 3.1e-39 134.8 29.0 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family TauD PF02668.16 OAG38215.1 - 3.7e-57 194.1 0.9 4.3e-57 193.9 0.9 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family adh_short PF00106.25 OAG38216.1 - 0.0018 17.7 0.0 0.051 13.0 0.0 2.8 1 1 0 1 1 1 1 short chain dehydrogenase FGGY_C PF02782.16 OAG38217.1 - 6.3e-71 238.2 0.3 1.1e-70 237.4 0.3 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 OAG38217.1 - 8.8e-61 205.6 0.0 1.2e-60 205.1 0.0 1.1 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain DUF3429 PF11911.8 OAG38218.1 - 3.3e-43 147.4 12.7 4.4e-43 147.0 12.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) COX6A PF02046.15 OAG38219.1 - 1.5e-52 176.8 0.1 1.8e-52 176.5 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa ANAPC5 PF12862.7 OAG38220.1 - 3e-35 120.2 3.8 8e-35 118.8 3.8 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 5 TPR_19 PF14559.6 OAG38220.1 - 0.0055 17.2 9.3 0.62 10.6 0.0 4.2 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 OAG38220.1 - 0.02 14.7 8.9 0.16 11.9 1.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 OAG38220.1 - 0.12 13.1 14.3 6.2 7.7 0.2 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 OAG38220.1 - 0.16 12.3 17.5 1.2 9.4 4.2 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 OAG38220.1 - 5.8 7.2 7.0 13 6.0 0.2 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat SAICAR_synt PF01259.18 OAG38221.1 - 1.9e-102 342.2 0.0 2.2e-102 342.0 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase CIA30 PF08547.12 OAG38222.1 - 5.1e-40 137.1 0.0 1.1e-39 136.0 0.0 1.5 1 1 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) RRM_1 PF00076.22 OAG38223.1 - 3.6e-26 90.8 0.1 6.9e-14 51.4 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 OAG38223.1 - 0.009 16.2 0.0 6.3 7.1 0.0 2.3 2 0 0 2 2 2 2 RRM-like domain Ank_4 PF13637.6 OAG38224.1 - 2.6e-10 40.6 0.8 1.2e-06 28.9 0.1 3.4 3 1 1 4 4 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 OAG38224.1 - 2.2e-08 34.6 1.0 0.0015 19.1 0.0 2.9 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OAG38224.1 - 2.1e-06 27.6 2.7 0.0094 16.4 0.1 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 OAG38224.1 - 2.4e-06 27.7 3.1 0.00014 22.1 0.3 3.7 2 1 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 OAG38224.1 - 2.4e-05 24.5 0.9 9.9e-05 22.6 0.2 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) KilA-N PF04383.13 OAG38224.1 - 4.9e-05 23.1 0.2 0.0003 20.6 0.2 2.2 1 1 0 1 1 1 1 KilA-N domain TMF_TATA_bd PF12325.8 OAG38224.1 - 0.00012 22.3 3.5 0.00012 22.3 3.5 2.4 3 0 0 3 3 3 1 TATA element modulatory factor 1 TATA binding DUF4201 PF13870.6 OAG38224.1 - 0.014 15.2 4.7 0.03 14.1 4.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) FliJ PF02050.16 OAG38224.1 - 0.076 13.2 5.9 0.21 11.8 5.9 1.8 1 0 0 1 1 1 0 Flagellar FliJ protein 3HCDH_N PF02737.18 OAG38224.1 - 0.13 12.2 0.2 0.24 11.3 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Tup_N PF08581.10 OAG38224.1 - 1.5 9.2 10.4 0.45 10.9 0.7 3.4 4 0 0 4 4 4 0 Tup N-terminal ADH_zinc_N_2 PF13602.6 OAG38226.1 - 2.3e-28 99.9 0.0 3.8e-28 99.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 OAG38226.1 - 4.8e-17 62.2 0.0 9.2e-17 61.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Acetyltransf_7 PF13508.7 OAG38227.1 - 7.9e-09 35.8 0.0 1.2e-08 35.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAG38227.1 - 1.2e-08 35.2 0.0 2.3e-08 34.3 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OAG38227.1 - 1e-06 28.7 0.0 1.4e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Abhydrolase_3 PF07859.13 OAG38228.1 - 6.4e-33 114.4 0.0 8.7e-33 114.0 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 OAG38228.1 - 1.1e-06 27.8 0.0 1.5e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_2 PF02230.16 OAG38228.1 - 0.15 11.8 0.0 0.24 11.2 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase adh_short_C2 PF13561.6 OAG38229.1 - 2.9e-49 167.8 0.1 3.5e-49 167.5 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG38229.1 - 5.2e-41 140.2 0.1 6.8e-41 139.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG38229.1 - 1.8e-10 41.0 0.1 4.2e-09 36.6 0.1 2.0 2 0 0 2 2 2 1 KR domain ING PF12998.7 OAG38230.1 - 3.3e-10 40.4 0.9 0.00067 20.2 0.0 2.7 3 0 0 3 3 3 2 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 OAG38230.1 - 1.3e-05 25.0 8.5 2.2e-05 24.3 8.5 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 OAG38230.1 - 0.039 13.5 3.3 0.073 12.6 3.3 1.4 1 0 0 1 1 1 0 PHD-finger zf-HC5HC2H PF13771.6 OAG38230.1 - 0.21 11.9 1.4 0.46 10.8 1.4 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain Drf_GBD PF06371.13 OAG38231.1 - 3.2e-13 49.7 0.4 1.3e-07 31.4 0.0 2.3 2 0 0 2 2 2 2 Diaphanous GTPase-binding Domain GREB1 PF15782.5 OAG38231.1 - 5.5 4.0 6.6 8.4 3.4 6.6 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Sugar_tr PF00083.24 OAG38233.1 - 1.7e-38 132.7 24.4 1.4e-37 129.6 24.4 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG38233.1 - 7.8e-29 100.7 31.5 4.2e-23 81.8 18.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Mito_carr PF00153.27 OAG38235.1 - 6.6e-56 186.2 2.0 3.2e-20 71.9 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 OAG38235.1 - 0.15 11.2 9.8 7.1 5.7 0.1 4.0 2 2 1 4 4 4 0 Gammaproteobacterial serine protease PT-VENN PF04829.13 OAG38235.1 - 3.3 7.8 5.0 46 4.2 0.0 3.5 4 0 0 4 4 4 0 Pre-toxin domain with VENN motif SWIRM PF04433.17 OAG38236.1 - 2.2e-31 108.0 0.1 5.2e-31 106.8 0.1 1.7 1 0 0 1 1 1 1 SWIRM domain SWIRM-assoc_1 PF16495.5 OAG38236.1 - 4.1e-30 103.6 8.6 1.2e-29 102.1 8.6 1.8 1 0 0 1 1 1 1 SWIRM-associated region 1 Myb_DNA-binding PF00249.31 OAG38236.1 - 1.2e-11 44.5 0.1 2.4e-11 43.6 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OAG38236.1 - 3.2e-08 33.7 0.1 6.5e-08 32.7 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OAG38236.1 - 0.011 15.6 0.8 0.041 13.8 0.0 2.2 2 0 0 2 2 2 0 Myb DNA-binding like ZZ PF00569.17 OAG38236.1 - 0.066 13.0 0.2 0.066 13.0 0.2 1.9 2 0 0 2 2 2 0 Zinc finger, ZZ type AAA_9 PF12781.7 OAG38236.1 - 0.12 11.5 1.2 0.2 10.7 1.2 1.3 1 0 0 1 1 1 0 ATP-binding dynein motor region BTB PF00651.31 OAG38237.1 - 1.4e-05 25.3 0.0 2.2e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain AAA PF00004.29 OAG38238.1 - 2e-12 47.7 0.2 9.3e-12 45.5 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OAG38238.1 - 1.2e-06 28.8 0.0 5.5e-06 26.7 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 OAG38238.1 - 1.5e-05 25.0 0.0 5.5e-05 23.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OAG38238.1 - 2.3e-05 24.9 0.0 0.00093 19.6 0.0 3.1 2 1 1 3 3 3 1 AAA ATPase domain Rad17 PF03215.15 OAG38238.1 - 2.4e-05 24.4 0.2 0.00022 21.2 0.0 2.2 2 0 0 2 2 2 1 Rad17 P-loop domain RuvB_N PF05496.12 OAG38238.1 - 8.7e-05 22.3 0.0 0.00018 21.3 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 OAG38238.1 - 0.00038 20.6 0.2 0.0021 18.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 OAG38238.1 - 0.00066 19.7 0.0 0.002 18.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 OAG38238.1 - 0.0067 15.7 0.0 0.017 14.4 0.0 1.7 1 0 0 1 1 1 1 Zeta toxin AAA_30 PF13604.6 OAG38238.1 - 0.022 14.5 0.1 0.049 13.4 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 OAG38238.1 - 0.037 14.6 0.0 0.15 12.6 0.0 2.1 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 OAG38238.1 - 0.042 13.8 0.0 0.13 12.2 0.0 1.8 2 0 0 2 2 2 0 NTPase AAA_24 PF13479.6 OAG38238.1 - 0.09 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 OAG38238.1 - 0.12 12.3 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_19 PF13245.6 OAG38238.1 - 0.14 12.5 0.1 0.83 10.0 0.0 2.3 3 0 0 3 3 2 0 AAA domain TsaE PF02367.17 OAG38238.1 - 0.15 12.1 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_membrane_2 PF06472.15 OAG38239.1 - 2.2e-103 345.4 1.7 3.5e-103 344.7 1.7 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 OAG38239.1 - 3.8e-18 66.3 0.0 9.2e-18 65.1 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 OAG38239.1 - 5.2e-05 23.2 0.1 0.00015 21.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 OAG38239.1 - 0.0083 16.7 0.5 0.0083 16.7 0.5 2.7 2 1 0 2 2 2 1 AAA domain SMC_N PF02463.19 OAG38239.1 - 0.0089 15.5 0.2 0.14 11.6 0.1 2.4 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 OAG38239.1 - 0.017 14.9 0.0 0.037 13.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_27 PF13514.6 OAG38239.1 - 0.019 14.6 1.2 0.48 10.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain Reticulon PF02453.17 OAG38239.1 - 0.035 14.1 0.5 0.16 11.9 0.5 2.0 1 1 0 1 1 1 0 Reticulon RuvB_N PF05496.12 OAG38239.1 - 0.084 12.6 0.0 1.4 8.6 0.0 2.8 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 OAG38239.1 - 0.11 12.4 0.1 0.27 11.1 0.1 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain Mg_chelatase PF01078.21 OAG38239.1 - 0.15 11.5 0.0 0.29 10.5 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_15 PF13175.6 OAG38239.1 - 0.17 11.6 0.1 0.43 10.2 0.1 1.6 1 0 0 1 1 1 0 AAA ATPase domain Hemerythrin PF01814.23 OAG38241.1 - 8.1e-07 29.7 0.2 1.6e-06 28.8 0.2 1.5 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain HAD_2 PF13419.6 OAG38242.1 - 2e-09 37.8 0.0 2.8e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OAG38242.1 - 1.9e-08 34.8 0.0 2e-07 31.5 0.0 1.9 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase ERbeta_N PF12497.8 OAG38243.1 - 0.084 12.7 0.1 0.23 11.2 0.1 1.7 1 0 0 1 1 1 0 Estrogen receptor beta Ank_2 PF12796.7 OAG38245.1 - 2.2e-65 217.2 9.9 1.1e-12 48.4 0.0 7.8 3 1 4 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAG38245.1 - 1.4e-59 197.8 23.5 6.5e-11 42.5 0.1 11.8 3 1 10 13 13 12 12 Ankyrin repeats (many copies) Ank PF00023.30 OAG38245.1 - 6.4e-55 181.3 18.2 6.9e-05 23.1 0.0 13.5 13 0 0 13 13 13 11 Ankyrin repeat Ank_3 PF13606.6 OAG38245.1 - 4e-51 165.0 2.2 0.0011 19.2 0.0 13.4 14 0 0 14 14 14 10 Ankyrin repeat Ank_5 PF13857.6 OAG38245.1 - 1e-43 146.8 16.1 2.8e-05 24.3 0.1 10.5 4 2 6 10 10 10 9 Ankyrin repeats (many copies) Helo_like_N PF17111.5 OAG38245.1 - 6.1e-09 35.5 3.5 1.2e-08 34.6 3.5 1.5 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins NACHT PF05729.12 OAG38245.1 - 2.5e-06 27.5 0.1 8.2e-06 25.8 0.1 1.9 1 0 0 1 1 1 1 NACHT domain SesA PF17107.5 OAG38245.1 - 0.00022 21.4 0.6 0.001 19.2 0.1 2.4 2 0 0 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases Vps35 PF03635.17 OAG38245.1 - 0.016 13.7 0.9 0.028 13.0 0.9 1.2 1 0 0 1 1 1 0 Vacuolar protein sorting-associated protein 35 DUF1857 PF08982.11 OAG38245.1 - 0.15 11.9 0.1 0.39 10.6 0.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1857) Arg_repressor PF01316.21 OAG38245.1 - 0.74 9.6 2.8 49 3.8 0.1 4.4 5 0 0 5 5 5 0 Arginine repressor, DNA binding domain Chitin_synth_2 PF03142.15 OAG38246.1 - 2.4e-230 765.7 0.0 3.1e-230 765.3 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase DEK_C PF08766.11 OAG38246.1 - 2.2e-15 56.3 0.1 1e-14 54.2 0.1 2.1 2 0 0 2 2 2 1 DEK C terminal domain Cyt-b5 PF00173.28 OAG38246.1 - 2.7e-13 49.9 0.7 5.1e-09 36.2 0.0 2.8 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_tranf_2_3 PF13641.6 OAG38246.1 - 7.7e-12 45.6 0.0 3e-11 43.6 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 OAG38246.1 - 7.8e-12 45.5 2.2 2.4e-11 43.9 2.2 1.9 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Myosin_head PF00063.21 OAG38246.1 - 1.1e-07 30.5 0.0 2.5e-07 29.4 0.0 1.4 2 0 0 2 2 2 1 Myosin head (motor domain) Glyco_transf_21 PF13506.6 OAG38246.1 - 0.00043 19.8 0.0 0.0012 18.3 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 OAG38246.1 - 0.0058 16.4 0.0 0.65 9.8 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 Chitin_synth_2 PF03142.15 OAG38247.1 - 1.1e-246 819.5 0.9 1.5e-246 819.1 0.9 1.2 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 OAG38247.1 - 3.9e-74 250.1 0.0 1.8e-73 247.9 0.0 1.8 1 1 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.28 OAG38247.1 - 8.9e-17 61.0 0.1 7.5e-14 51.6 0.0 3.3 2 1 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain PLDc_2 PF13091.6 OAG38247.1 - 7.8e-14 51.7 0.1 7.5e-06 25.9 0.0 3.1 2 0 0 2 2 2 2 PLD-like domain DEK_C PF08766.11 OAG38247.1 - 9.9e-14 51.0 0.2 2.5e-13 49.7 0.2 1.7 1 0 0 1 1 1 1 DEK C terminal domain Glyco_trans_2_3 PF13632.6 OAG38247.1 - 4.8e-13 49.5 2.9 1.1e-12 48.2 2.9 1.7 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 OAG38247.1 - 4.1e-11 43.2 0.1 7.2e-10 39.1 0.1 2.5 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 OAG38247.1 - 5.3e-05 23.1 0.0 0.035 13.9 0.0 2.7 2 0 0 2 2 2 2 Glycosyl transferase family 2 PLDc PF00614.22 OAG38247.1 - 0.021 15.0 0.3 0.78 10.0 0.0 3.0 2 0 0 2 2 2 0 Phospholipase D Active site motif Glyco_transf_21 PF13506.6 OAG38247.1 - 0.036 13.6 0.7 0.7 9.3 0.6 2.7 2 1 0 2 2 2 0 Glycosyl transferase family 21 AAA_22 PF13401.6 OAG38247.1 - 0.04 14.2 0.0 0.14 12.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 OAG38247.1 - 0.15 12.0 0.0 0.34 10.8 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase PSDC PF12588.8 OAG38248.1 - 1.3e-41 141.9 0.0 2.1e-41 141.2 0.0 1.4 1 0 0 1 1 1 1 Phophatidylserine decarboxylase PS_Dcarbxylase PF02666.15 OAG38248.1 - 3.4e-35 121.4 0.0 4.7e-35 120.9 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase RnfC_N PF13375.6 OAG38248.1 - 0.00021 21.2 0.0 0.15 12.0 0.0 2.4 2 0 0 2 2 2 2 RnfC Barrel sandwich hybrid domain TPP_enzyme_N PF02776.18 OAG38249.1 - 8e-38 129.7 0.0 1.9e-36 125.3 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 OAG38249.1 - 1.1e-19 70.7 0.0 2.4e-19 69.6 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 OAG38249.1 - 5.5e-09 35.9 0.0 1.5e-08 34.5 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain Sugar_tr PF00083.24 OAG38250.1 - 3e-119 398.8 23.7 3.5e-119 398.6 23.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG38250.1 - 2.2e-24 86.1 50.6 9.5e-20 70.8 25.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MCM PF00493.23 OAG38251.1 - 3.7e-98 327.1 0.1 6.5e-98 326.3 0.1 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 OAG38251.1 - 5.5e-31 107.0 0.0 1e-30 106.2 0.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 OAG38251.1 - 1.8e-24 86.0 1.9 4.1e-24 84.8 1.9 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 OAG38251.1 - 1.2e-10 41.8 0.0 3.5e-10 40.4 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 OAG38251.1 - 1.2e-06 28.1 0.0 1.4e-05 24.6 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 OAG38251.1 - 0.0044 16.9 0.0 0.013 15.4 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 OAG38251.1 - 0.1 12.3 0.0 0.25 11.0 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF2937 PF11157.8 OAG38252.1 - 0.11 12.3 4.7 0.18 11.5 4.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) Transket_pyr PF02779.24 OAG38254.1 - 1.6e-65 220.1 0.0 3.2e-65 219.1 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 OAG38254.1 - 6.8e-59 199.3 0.0 1e-58 198.7 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 OAG38254.1 - 9.3e-58 194.2 0.0 2.4e-57 192.9 0.0 1.7 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 OAG38254.1 - 1.3e-20 72.7 1.3 2.7e-20 71.7 1.3 1.6 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus DUF2680 PF10925.8 OAG38254.1 - 0.11 12.5 0.5 1.1 9.4 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2680) Nramp PF01566.18 OAG38256.1 - 3.2e-90 302.7 16.3 3.2e-90 302.7 16.3 1.4 2 0 0 2 2 2 1 Natural resistance-associated macrophage protein Translin PF01997.16 OAG38257.1 - 9.6e-48 162.9 0.1 1.3e-47 162.5 0.1 1.1 1 0 0 1 1 1 1 Translin family FleQ PF06490.11 OAG38257.1 - 0.11 12.9 0.1 0.23 11.8 0.1 1.5 1 0 0 1 1 1 0 Flagellar regulatory protein FleQ MMR_HSR1_C PF08438.10 OAG38260.1 - 4.3e-37 127.1 0.0 7.2e-37 126.4 0.0 1.4 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.23 OAG38260.1 - 2.4e-20 72.7 0.0 6.6e-20 71.3 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OAG38260.1 - 5e-09 35.9 0.0 1.4e-07 31.1 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 OAG38260.1 - 0.011 15.3 0.3 1.4 8.4 0.1 2.6 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 OAG38260.1 - 0.052 13.6 0.5 0.15 12.1 0.3 1.9 2 0 0 2 2 2 0 Dynamin family AAA_18 PF13238.6 OAG38260.1 - 0.086 13.4 0.1 3 8.4 0.0 2.6 2 1 0 2 2 2 0 AAA domain Ploopntkinase3 PF18751.1 OAG38260.1 - 0.13 12.1 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 AAA_33 PF13671.6 OAG38260.1 - 0.14 12.3 0.1 8.8 6.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.10 OAG38260.1 - 0.15 11.5 0.0 0.29 10.5 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 adh_short PF00106.25 OAG38262.1 - 5.3e-90 300.1 19.1 4.1e-48 163.4 5.5 3.6 3 1 0 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAG38262.1 - 1.2e-69 234.5 16.5 4.5e-37 127.9 5.7 3.0 2 2 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG38262.1 - 8.6e-31 107.2 7.9 5.4e-15 55.8 1.5 2.4 2 0 0 2 2 2 2 KR domain MaoC_dehydratas PF01575.19 OAG38262.1 - 8.2e-28 96.4 0.0 1.6e-27 95.5 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain PglL_A PF15864.5 OAG38262.1 - 4.8 7.0 6.4 5.4 6.8 1.0 2.6 2 0 0 2 2 2 0 Protein glycosylation ligase Fungal_trans PF04082.18 OAG38263.1 - 2.4e-40 138.3 3.5 4.3e-40 137.4 3.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG38263.1 - 5.1e-08 32.9 14.7 9.8e-08 32.0 14.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Lzipper-MIP1 PF14389.6 OAG38263.1 - 0.03 14.6 1.1 0.14 12.5 1.1 2.1 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 NYD-SP28 PF14772.6 OAG38263.1 - 0.08 13.0 1.1 0.44 10.6 0.1 2.4 2 0 0 2 2 2 0 Sperm tail bZIP_1 PF00170.21 OAG38263.1 - 0.17 12.0 0.1 0.62 10.2 0.1 1.9 1 0 0 1 1 1 0 bZIP transcription factor SET PF00856.28 OAG38264.1 - 8.2e-06 26.3 0.0 2e-05 25.1 0.0 1.7 2 0 0 2 2 2 1 SET domain Stealth_CR2 PF11380.8 OAG38265.1 - 0.049 13.8 0.0 0.074 13.2 0.0 1.3 1 0 0 1 1 1 0 Stealth protein CR2, conserved region 2 Aspzincin_M35 PF14521.6 OAG38266.1 - 0.07 13.7 0.2 0.88 10.1 0.1 2.6 4 0 0 4 4 4 0 Lysine-specific metallo-endopeptidase Zn_clus PF00172.18 OAG38269.1 - 0.039 14.1 13.8 0.081 13.1 13.8 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain ABC_tran PF00005.27 OAG38270.1 - 7.3e-30 104.3 0.0 1.2e-29 103.6 0.0 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 OAG38270.1 - 1.3e-08 34.5 0.1 7.4e-07 28.8 0.1 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 OAG38270.1 - 0.00011 22.2 0.1 0.00028 20.8 0.1 1.8 1 1 0 1 1 1 1 RsgA GTPase Zeta_toxin PF06414.12 OAG38270.1 - 0.0061 15.9 0.0 0.012 14.9 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_23 PF13476.6 OAG38270.1 - 0.038 14.5 0.0 0.09 13.3 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 OAG38270.1 - 0.041 13.6 0.1 0.11 12.3 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.29 OAG38270.1 - 0.062 13.7 0.0 0.33 11.4 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OAG38270.1 - 0.082 13.3 0.1 0.21 11.9 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 OAG38270.1 - 0.13 11.8 0.0 0.32 10.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region MFS_1 PF07690.16 OAG38272.1 - 2.4e-34 118.8 21.1 1.8e-33 115.9 21.9 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily Abhydrolase_9_N PF15420.6 OAG38272.1 - 0.0031 17.5 0.4 0.0031 17.5 0.4 2.8 2 1 0 2 2 2 1 Alpha/beta-hydrolase family N-terminus FAM176 PF14851.6 OAG38272.1 - 0.0035 17.0 0.3 0.02 14.5 0.0 2.2 2 0 0 2 2 2 1 FAM176 family FMO-like PF00743.19 OAG38273.1 - 1.4e-38 132.6 0.0 6.3e-18 64.5 0.0 3.3 3 1 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OAG38273.1 - 1.7e-15 57.0 0.0 2.1e-08 33.8 0.0 3.3 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAG38273.1 - 6.3e-15 55.2 0.0 2.2e-13 50.1 0.0 2.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAG38273.1 - 5.3e-10 39.4 1.3 2.1e-07 30.9 0.4 3.0 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 OAG38273.1 - 1.7e-09 37.9 2.3 7.9e-06 25.9 0.1 4.0 4 1 0 4 4 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 OAG38273.1 - 4.5e-09 36.4 0.0 1.9e-08 34.4 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 OAG38273.1 - 1.5e-07 30.9 0.0 0.0033 16.6 0.0 3.7 3 1 1 4 4 4 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 OAG38273.1 - 1.6e-06 28.6 0.8 0.00011 22.6 0.2 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 OAG38273.1 - 1.2e-05 24.8 0.3 0.005 16.2 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Shikimate_DH PF01488.20 OAG38273.1 - 1.7e-05 24.9 0.2 0.011 15.8 0.1 2.7 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.14 OAG38273.1 - 3.6e-05 22.7 0.4 0.0071 15.1 0.3 2.3 2 0 0 2 2 2 2 HI0933-like protein Thi4 PF01946.17 OAG38273.1 - 0.00083 18.7 0.1 0.0018 17.5 0.1 1.5 1 0 0 1 1 1 1 Thi4 family NAD_binding_2 PF03446.15 OAG38273.1 - 0.001 19.2 0.3 0.034 14.3 0.0 2.8 3 0 0 3 3 3 1 NAD binding domain of 6-phosphogluconate dehydrogenase FAD_binding_2 PF00890.24 OAG38273.1 - 0.0017 17.5 0.2 0.0072 15.5 0.3 1.8 2 0 0 2 2 2 1 FAD binding domain 3HCDH_N PF02737.18 OAG38273.1 - 0.004 17.1 0.3 0.0084 16.0 0.3 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.7 OAG38273.1 - 0.0043 16.4 1.3 0.021 14.2 0.3 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 OAG38273.1 - 0.0053 16.1 0.5 0.01 15.1 0.5 1.4 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 OAG38273.1 - 0.0077 15.5 0.2 0.048 12.9 0.1 2.1 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 OAG38273.1 - 0.032 13.6 0.0 7 6.0 0.0 2.5 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 OAG38273.1 - 0.052 13.2 0.5 0.16 11.6 0.5 1.8 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA GIDA PF01134.22 OAG38273.1 - 0.059 12.4 2.2 0.073 12.1 0.7 1.9 3 0 0 3 3 3 0 Glucose inhibited division protein A NAD_binding_7 PF13241.6 OAG38273.1 - 0.095 13.2 0.0 1.1 9.7 0.0 2.5 2 1 0 2 2 2 0 Putative NAD(P)-binding IlvN PF07991.12 OAG38273.1 - 0.099 12.2 0.0 0.27 10.8 0.0 1.7 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain TauD PF02668.16 OAG38274.1 - 1.1e-58 199.1 0.1 1.4e-58 198.8 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Corona_5a PF06336.11 OAG38276.1 - 0.086 12.8 0.1 0.16 11.9 0.1 1.4 1 0 0 1 1 1 0 Coronavirus 5a protein APH PF01636.23 OAG38277.1 - 1.7e-14 54.3 0.9 2.7e-14 53.7 0.7 1.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 OAG38277.1 - 0.00061 19.4 0.0 0.00088 18.9 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 OAG38277.1 - 0.0094 15.6 0.0 0.012 15.2 0.0 1.1 1 0 0 1 1 1 1 RIO1 family F-box PF00646.33 OAG38279.1 - 0.17 11.8 3.9 0.28 11.1 0.2 2.7 2 0 0 2 2 2 0 F-box domain DUF507 PF04368.13 OAG38280.1 - 0.11 12.4 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF507) NPV_P10 PF05531.12 OAG38280.1 - 0.2 12.2 2.2 9.9 6.7 0.7 2.6 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Pkinase_fungal PF17667.1 OAG38281.1 - 3.6e-134 447.6 0.0 9.3e-134 446.2 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Pkinase PF00069.25 OAG38281.1 - 4.9e-06 26.1 0.0 9.4e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 OAG38281.1 - 0.0096 15.9 0.0 0.067 13.1 0.0 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family MauJ PF17419.2 OAG38281.1 - 0.018 14.5 0.0 0.032 13.7 0.0 1.3 1 0 0 1 1 1 0 Methylamine utilization protein MauJ TPR_14 PF13428.6 OAG38281.1 - 0.038 14.8 0.5 0.34 11.9 0.2 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat F-box-like PF12937.7 OAG38282.1 - 0.0015 18.4 2.2 0.0029 17.5 0.2 2.7 3 0 0 3 3 3 1 F-box-like LRR_4 PF12799.7 OAG38282.1 - 0.079 13.4 0.5 15 6.2 0.0 3.3 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) Amidase_5 PF05382.13 OAG38285.1 - 0.0086 16.0 0.1 0.011 15.7 0.1 1.3 1 1 0 1 1 1 1 Bacteriophage peptidoglycan hydrolase Phenyl_P_gamma PF09662.10 OAG38287.1 - 0.013 15.6 0.0 0.022 14.9 0.0 1.4 1 0 0 1 1 1 0 Phenylphosphate carboxylase gamma subunit (Phenyl_P_gamma) CBFD_NFYB_HMF PF00808.23 OAG38290.1 - 8.6e-19 67.6 0.2 1.7e-18 66.7 0.2 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 OAG38290.1 - 1.2e-05 25.7 0.1 1.2e-05 25.7 0.1 2.1 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.13 OAG38290.1 - 0.00037 20.4 0.2 0.0022 17.9 0.1 2.0 2 0 0 2 2 2 1 Bromodomain associated LRRC37 PF15779.5 OAG38290.1 - 0.039 14.3 0.2 0.14 12.5 0.0 1.9 2 0 0 2 2 2 0 Leucine-rich repeat-containing protein 37 family CTD_bind PF04818.13 OAG38291.1 - 0.015 16.1 0.9 0.35 11.7 0.1 2.4 2 1 0 2 2 2 0 RNA polymerase II-binding domain. ABC_tran PF00005.27 OAG38294.1 - 2.3e-31 109.1 0.0 4.1e-31 108.3 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 OAG38294.1 - 1e-11 45.0 1.1 1.2e-11 44.8 0.3 1.5 2 0 0 2 2 2 1 ABC transporter transmembrane region AAA_16 PF13191.6 OAG38294.1 - 0.00082 19.8 0.0 0.0017 18.8 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 OAG38294.1 - 0.0062 16.6 0.0 0.016 15.3 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF87 PF01935.17 OAG38294.1 - 0.01 16.0 0.0 0.018 15.2 0.0 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain SMC_N PF02463.19 OAG38294.1 - 0.027 13.9 0.5 0.32 10.4 0.5 2.1 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain PRK PF00485.18 OAG38294.1 - 0.037 13.8 0.0 0.071 12.8 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_22 PF13401.6 OAG38294.1 - 0.038 14.3 0.0 0.094 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 OAG38294.1 - 0.048 14.2 0.0 0.15 12.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain DLIC PF05783.11 OAG38294.1 - 0.058 12.2 0.0 0.095 11.5 0.0 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) AAA_29 PF13555.6 OAG38294.1 - 0.11 12.3 0.1 0.37 10.6 0.1 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain Roc PF08477.13 OAG38294.1 - 0.11 12.8 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase NACHT PF05729.12 OAG38294.1 - 0.11 12.4 0.0 0.36 10.7 0.0 1.9 2 0 0 2 2 2 0 NACHT domain AAA_7 PF12775.7 OAG38294.1 - 0.17 11.4 0.0 0.29 10.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 OAG38294.1 - 0.18 11.5 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 OAG38294.1 - 0.21 11.7 0.1 0.85 9.8 0.1 1.8 1 1 1 2 2 2 0 AAA domain DIMCO_N PF16844.5 OAG38295.1 - 0.059 13.7 0.4 0.2 12.0 0.1 1.9 2 0 0 2 2 2 0 Dinitrogenase iron-molybdenum cofactor, N-terminal Pkinase PF00069.25 OAG38297.1 - 2.8e-28 99.0 0.0 5.1e-28 98.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG38297.1 - 2.6e-13 49.9 0.0 5.2e-13 48.9 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase CENP-F_leu_zip PF10473.9 OAG38298.1 - 0.00011 22.3 7.0 0.00011 22.3 7.0 3.9 2 1 0 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.11 OAG38298.1 - 0.0046 15.9 4.2 0.0046 15.9 4.2 4.5 2 1 2 4 4 4 3 Spc7 kinetochore protein FlaC_arch PF05377.11 OAG38298.1 - 0.37 11.2 11.8 6.4 7.3 0.1 5.7 5 0 0 5 5 5 0 Flagella accessory protein C (FlaC) MscS_porin PF12795.7 OAG38298.1 - 0.78 9.2 66.3 0.088 12.3 18.0 3.7 2 1 1 3 3 3 0 Mechanosensitive ion channel porin domain YfhO PF09586.10 OAG38298.1 - 1.2 7.2 8.1 1.6 6.9 8.1 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO HALZ PF02183.18 OAG38298.1 - 1.4 9.2 8.2 12 6.2 0.0 4.5 4 0 0 4 4 4 0 Homeobox associated leucine zipper Ferrochelatase PF00762.19 OAG38301.1 - 7.5e-100 334.1 0.0 8.8e-100 333.9 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase Ku PF02735.16 OAG38302.1 - 1.4e-44 152.3 0.0 3.5e-44 150.9 0.0 1.7 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 OAG38302.1 - 1.3e-33 116.6 0.0 1.9e-33 116.0 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 OAG38302.1 - 2.7e-26 92.1 0.2 1.1e-25 90.2 0.2 2.1 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm SAP PF02037.27 OAG38302.1 - 5.2e-11 42.0 0.0 9.8e-11 41.2 0.0 1.5 1 0 0 1 1 1 1 SAP domain FRG1 PF06229.12 OAG38302.1 - 0.031 14.0 0.1 0.42 10.3 0.0 2.2 2 0 0 2 2 2 0 FRG1-like domain Abhydrolase_1 PF00561.20 OAG38303.1 - 1e-23 84.3 0.2 5.8e-23 81.8 0.2 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 OAG38303.1 - 1.1e-22 79.3 0.0 2.3e-22 78.3 0.0 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Hydrolase_4 PF12146.8 OAG38303.1 - 7.2e-06 25.4 0.0 0.00093 18.5 0.0 2.6 2 1 0 2 2 2 1 Serine aminopeptidase, S33 FSH1 PF03959.13 OAG38303.1 - 0.00036 20.2 0.0 0.18 11.4 0.0 2.3 2 0 0 2 2 2 2 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 OAG38303.1 - 0.16 11.8 0.0 18 5.1 0.0 2.4 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Asp PF00026.23 OAG38304.1 - 8.6e-72 242.2 2.4 1.2e-71 241.8 2.4 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OAG38304.1 - 1.9e-12 47.8 3.0 6.7e-07 29.7 0.2 3.2 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 OAG38304.1 - 1.4e-06 28.9 1.0 0.031 14.9 0.2 3.8 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 OAG38304.1 - 0.00025 21.6 0.1 0.17 12.4 0.0 3.4 2 1 0 2 2 2 1 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 OAG38304.1 - 0.0091 15.8 0.3 0.05 13.4 0.0 2.3 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal TPR_14 PF13428.6 OAG38305.1 - 2.8e-05 24.6 10.2 0.21 12.5 0.1 5.7 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.6 OAG38305.1 - 0.00019 21.4 3.5 0.45 10.8 0.0 5.6 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_19 PF14559.6 OAG38305.1 - 0.0022 18.5 6.9 2.7 8.6 0.0 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 OAG38305.1 - 0.0072 16.6 0.2 3 8.4 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 OAG38305.1 - 0.018 15.1 12.8 5.4 7.4 0.1 5.9 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_6 PF13174.6 OAG38305.1 - 0.15 12.8 3.8 6.1 7.7 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 OAG38305.1 - 0.16 12.2 15.3 0.7 10.2 0.5 6.3 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_16 PF13432.6 OAG38305.1 - 0.69 10.6 9.0 5 7.9 0.1 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 OAG38305.1 - 1.7 8.9 9.0 30 5.0 0.2 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_4 PF07721.14 OAG38305.1 - 5.8 7.9 6.2 4.1 8.3 1.1 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat RIX1 PF08167.12 OAG38306.1 - 8.3e-42 143.1 6.4 3.4e-41 141.1 3.8 2.8 3 0 0 3 3 3 1 rRNA processing/ribosome biogenesis DUF4455 PF14643.6 OAG38306.1 - 0.16 10.6 0.2 0.31 9.7 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4455) SNF2_N PF00176.23 OAG38307.1 - 1e-68 231.6 0.1 1.5e-68 231.1 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.11 OAG38307.1 - 2e-16 59.7 0.0 3.8e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.31 OAG38307.1 - 1e-13 51.6 0.0 2.7e-13 50.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.6 OAG38307.1 - 1.2e-09 37.9 14.1 3e-09 36.6 14.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OAG38307.1 - 2.3e-08 33.8 11.8 2.3e-08 33.8 11.8 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAG38307.1 - 1.6e-07 31.5 13.3 1.6e-07 31.5 13.3 2.0 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 OAG38307.1 - 4.1e-07 29.9 9.7 1.2e-06 28.4 9.7 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OAG38307.1 - 8.7e-07 28.7 13.8 8.7e-07 28.7 13.8 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAG38307.1 - 5.9e-06 26.1 11.5 1.3e-05 25.1 11.5 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 OAG38307.1 - 8.8e-06 25.8 11.9 1.8e-05 24.8 11.9 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 OAG38307.1 - 4.5e-05 23.6 8.6 0.00011 22.5 8.6 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 OAG38307.1 - 7e-05 22.6 11.8 0.00015 21.5 11.8 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 DEAD PF00270.29 OAG38307.1 - 0.00051 19.9 0.0 0.0011 18.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 OAG38307.1 - 0.00079 18.7 0.8 0.025 13.8 0.0 3.4 4 1 0 4 4 4 1 Class II histone deacetylase complex subunits 2 and 3 zf-ANAPC11 PF12861.7 OAG38307.1 - 0.0024 17.9 2.1 0.0061 16.6 2.1 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger U-box PF04564.15 OAG38307.1 - 0.011 16.0 0.0 0.036 14.2 0.0 1.9 1 0 0 1 1 1 0 U-box domain zf-RING_10 PF16685.5 OAG38307.1 - 0.012 15.7 9.0 0.03 14.4 9.0 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 DUF2913 PF11140.8 OAG38307.1 - 0.015 15.1 0.3 0.015 15.1 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2913) zf-RING_4 PF14570.6 OAG38307.1 - 0.045 13.6 10.3 0.089 12.6 10.3 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Topoisom_I_N PF02919.15 OAG38307.1 - 0.075 12.5 0.7 4.2 6.8 0.8 2.4 2 0 0 2 2 2 0 Eukaryotic DNA topoisomerase I, DNA binding fragment zf-RING_6 PF14835.6 OAG38307.1 - 0.12 12.3 5.7 0.26 11.2 5.7 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DUF1272 PF06906.11 OAG38307.1 - 0.17 12.0 6.9 0.39 10.8 6.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-RING_11 PF17123.5 OAG38307.1 - 0.2 11.4 8.2 0.91 9.3 8.2 2.3 1 0 0 1 1 1 0 RING-like zinc finger zf-Nse PF11789.8 OAG38307.1 - 0.29 11.0 10.2 0.23 11.3 8.2 1.9 2 0 0 2 2 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_5 PF17121.5 OAG38307.1 - 0.71 9.8 4.5 3.1 7.8 4.5 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Glyco_transf_8 PF01501.20 OAG38308.1 - 2.3e-22 79.8 0.0 6.8e-22 78.2 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 OAG38308.1 - 0.26 10.6 0.0 0.26 10.6 0.0 1.8 2 0 0 2 2 2 0 Mannosyltransferase putative Presenilin PF01080.17 OAG38308.1 - 0.36 9.5 2.3 0.52 9.0 2.3 1.2 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 OAG38308.1 - 0.57 9.3 7.2 0.82 8.8 7.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter FAM76 PF16046.5 OAG38308.1 - 5.8 6.2 7.6 9.6 5.5 7.6 1.2 1 0 0 1 1 1 0 FAM76 protein V_ATPase_I PF01496.19 OAG38308.1 - 8.6 4.1 5.7 12 3.6 5.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ferric_reduct PF01794.19 OAG38309.1 - 2e-17 63.5 12.4 2e-17 63.5 12.4 2.1 1 1 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 OAG38309.1 - 2.3e-12 47.3 0.0 3.7e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 OAG38309.1 - 0.0012 18.9 0.0 0.0027 17.8 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain BatA PF07584.11 OAG38309.1 - 8.4 6.8 10.9 0.37 11.2 0.3 3.7 4 0 0 4 4 4 0 Aerotolerance regulator N-terminal Abhydrolase_1 PF00561.20 OAG38311.1 - 2.9e-15 56.6 0.0 2e-13 50.6 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG38311.1 - 6.7e-14 53.0 0.0 3.7e-13 50.6 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG38311.1 - 6.1e-07 28.9 0.0 2.3e-05 23.8 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 EHN PF06441.12 OAG38311.1 - 0.0038 17.6 0.7 0.0081 16.5 0.1 1.9 2 0 0 2 2 2 1 Epoxide hydrolase N terminus CYSTM PF12734.7 OAG38312.1 - 2.1 8.8 57.0 5.3e+03 -2.2 57.0 4.5 1 1 0 1 1 1 0 Cysteine-rich TM module stress tolerance Tmemb_cc2 PF10267.9 OAG38313.1 - 0.022 13.9 3.7 0.033 13.4 3.7 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Pro_CA PF00484.19 OAG38313.1 - 0.03 14.6 0.6 0.057 13.7 0.6 1.5 1 0 0 1 1 1 0 Carbonic anhydrase BLOC1_2 PF10046.9 OAG38313.1 - 0.084 13.2 0.5 4.2 7.7 0.0 2.4 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Phage_Mu_Gam PF07352.12 OAG38313.1 - 0.085 12.8 0.6 0.15 12.0 0.6 1.3 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein Fib_alpha PF08702.10 OAG38313.1 - 0.15 12.3 4.5 0.34 11.1 3.8 1.9 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF3375 PF11855.8 OAG38313.1 - 0.18 10.7 7.8 0.026 13.5 3.9 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3375) HIP1_clath_bdg PF16515.5 OAG38313.1 - 0.93 10.1 4.7 0.67 10.6 2.8 1.7 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 PhoU PF01895.19 OAG38313.1 - 1.2 9.6 5.4 0.25 11.8 1.3 2.0 2 0 0 2 2 2 0 PhoU domain VWA_3_C PF18571.1 OAG38313.1 - 2.2 8.2 4.3 3.2 7.7 3.0 1.9 2 0 0 2 2 2 0 von Willebrand factor type A C-terminal domain DUF4482 PF14818.6 OAG38313.1 - 3.2 8.6 12.0 38 5.1 7.5 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4482) Rotamase_3 PF13616.6 OAG38314.1 - 8.7e-05 23.1 0.6 0.0002 21.9 0.6 1.5 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 OAG38314.1 - 0.034 15.1 0.5 0.065 14.2 0.3 1.6 1 1 0 1 1 1 0 PPIC-type PPIASE domain SNF2_N PF00176.23 OAG38315.1 - 1.6e-64 217.8 2.1 3.2e-64 216.8 2.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.6 OAG38315.1 - 7.2e-48 162.3 19.4 7.2e-48 162.3 19.4 4.6 5 1 0 5 5 5 1 DNA-binding domain Helicase_C PF00271.31 OAG38315.1 - 1.2e-19 70.6 0.0 8.5e-19 67.9 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG38315.1 - 7.4e-07 29.3 0.0 7.4e-07 29.3 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 OAG38315.1 - 0.0017 18.2 0.1 0.0055 16.5 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 OAG38315.1 - 0.067 12.3 0.0 0.067 12.3 0.0 2.7 3 0 0 3 3 3 0 Class II histone deacetylase complex subunits 2 and 3 AA_permease_2 PF13520.6 OAG38316.1 - 8.6e-53 179.7 52.6 2.3e-52 178.3 52.6 1.6 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAG38316.1 - 1.2e-15 57.1 47.8 2.2e-15 56.2 47.8 1.4 1 1 0 1 1 1 1 Amino acid permease Pkinase PF00069.25 OAG38317.1 - 1.4e-50 172.1 0.0 4.2e-45 154.2 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAG38317.1 - 2.3e-19 69.7 0.1 5e-17 62.0 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase FHA PF00498.26 OAG38317.1 - 1.3e-10 41.5 0.1 3.2e-10 40.2 0.1 1.7 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.6 OAG38317.1 - 1.4e-07 31.1 0.0 4.5e-07 29.5 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 OAG38317.1 - 5.1e-07 28.8 0.1 1.9e-06 26.9 0.1 1.9 1 1 1 2 2 2 1 Fungal protein kinase Yop-YscD_cpl PF16697.5 OAG38317.1 - 0.00061 20.1 0.0 0.0016 18.7 0.0 1.7 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Kdo PF06293.14 OAG38317.1 - 0.0047 16.3 0.0 0.011 15.0 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Synthase_beta PF11421.8 OAG38317.1 - 0.073 13.8 7.7 0.28 11.9 2.5 3.4 2 0 0 2 2 2 0 ATP synthase F1 beta subunit Pox_ser-thr_kin PF05445.11 OAG38317.1 - 0.15 11.0 0.2 1.2 8.0 0.0 2.2 3 0 0 3 3 3 0 Poxvirus serine/threonine protein kinase Peptidase_M20 PF01546.28 OAG38318.1 - 3.3e-17 62.9 0.2 5.5e-17 62.1 0.2 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 OAG38318.1 - 3.5e-14 52.7 0.1 1.1e-13 51.1 0.1 1.8 1 0 0 1 1 1 1 Peptidase dimerisation domain Pyridox_ox_2 PF12900.7 OAG38319.1 - 3.8e-38 130.7 0.0 5.1e-38 130.2 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase tRNA-synt_1b PF00579.25 OAG38320.1 - 3.8e-28 98.7 0.0 8.1e-28 97.6 0.0 1.4 2 0 0 2 2 2 1 tRNA synthetases class I (W and Y) F-box-like_2 PF13013.6 OAG38321.1 - 0.054 13.5 0.0 0.088 12.8 0.0 1.6 1 1 0 1 1 1 0 F-box-like domain DIOX_N PF14226.6 OAG38322.1 - 1e-09 39.2 0.0 1.6e-09 38.5 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OAG38322.1 - 1.7e-09 38.1 0.0 4.9e-09 36.6 0.0 1.8 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Haem_oxygenas_2 PF14518.6 OAG38323.1 - 3.4e-34 118.2 0.1 3.4e-34 118.2 0.1 1.9 2 0 0 2 2 2 1 Iron-containing redox enzyme RNA_pol_I_A49 PF06870.12 OAG38325.1 - 9.2e-73 245.3 0.0 1.1e-72 245.1 0.0 1.0 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor OxoDH_E1alpha_N PF12573.8 OAG38325.1 - 0.099 12.4 1.0 0.26 11.1 1.0 1.7 1 0 0 1 1 1 0 2-oxoisovalerate dehydrogenase E1 alpha subunit N terminal Aminotran_1_2 PF00155.21 OAG38326.1 - 1.8e-85 287.3 0.0 2.5e-85 286.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 OAG38326.1 - 3.4e-06 25.8 0.0 5.7e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 OAG38326.1 - 7.5e-06 25.5 0.1 1.5e-05 24.5 0.1 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 OAG38326.1 - 8.1e-06 25.0 0.0 1.4e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 OAG38326.1 - 0.0039 16.5 0.2 0.0092 15.3 0.1 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase 5_nucleotid_C PF02872.18 OAG38327.1 - 2.4e-35 122.1 0.0 4.4e-35 121.2 0.0 1.4 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 OAG38327.1 - 4.8e-06 27.2 0.0 7.2e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase MFS_1 PF07690.16 OAG38329.1 - 1.8e-43 148.8 31.3 2.1e-37 128.8 9.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG38329.1 - 3.5e-09 36.0 11.7 2.9e-08 33.0 0.9 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.7 OAG38329.1 - 0.0012 17.8 5.1 0.0012 17.8 5.1 2.6 1 1 1 2 2 2 1 MFS_1 like family MFS_2 PF13347.6 OAG38329.1 - 0.0022 16.7 0.9 0.0022 16.7 0.9 2.7 2 1 0 2 2 2 1 MFS/sugar transport protein Folate_carrier PF01770.18 OAG38329.1 - 0.021 13.6 0.1 0.037 12.8 0.1 1.3 1 0 0 1 1 1 0 Reduced folate carrier FAD_binding_3 PF01494.19 OAG38330.1 - 3.4e-49 168.0 0.0 4.6e-49 167.5 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 OAG38330.1 - 0.0002 20.7 0.2 0.0057 16.0 0.2 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAG38330.1 - 0.00031 20.4 0.1 0.21 11.1 0.2 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAG38330.1 - 0.00046 20.4 1.3 0.00087 19.5 0.4 2.0 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 OAG38330.1 - 0.0033 16.2 0.0 0.015 14.0 0.1 1.8 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 OAG38330.1 - 0.0069 15.6 0.1 0.014 14.6 0.1 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 OAG38330.1 - 0.015 14.5 0.0 0.029 13.6 0.0 1.4 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAG38330.1 - 0.019 15.5 0.0 0.28 11.8 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAG38330.1 - 0.022 13.8 0.5 0.078 12.0 0.6 1.8 1 1 1 2 2 2 0 FAD binding domain FAD_oxidored PF12831.7 OAG38330.1 - 0.039 13.3 0.0 0.11 11.8 0.0 1.7 1 1 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 OAG38330.1 - 0.056 12.5 0.0 0.16 11.0 0.1 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein Amino_oxidase PF01593.24 OAG38330.1 - 0.069 12.4 0.1 0.64 9.2 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 OAG38330.1 - 0.15 12.1 0.0 0.86 9.6 0.1 2.2 3 0 0 3 3 3 0 FAD-NAD(P)-binding CNH PF00780.22 OAG38331.1 - 1.7e-65 221.4 0.0 2.6e-65 220.8 0.0 1.2 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.20 OAG38331.1 - 7.6e-31 107.8 0.0 2.7e-30 106.0 0.0 1.9 2 0 0 2 2 2 1 RhoGEF domain PH_5 PF15405.6 OAG38331.1 - 1.8e-12 47.5 0.0 2e-10 40.9 0.0 2.9 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 OAG38331.1 - 1.4e-06 28.7 0.0 0.00031 21.2 0.0 2.8 2 0 0 2 2 2 1 PH domain RabGAP-TBC PF00566.18 OAG38332.1 - 3.9e-46 157.4 0.0 6.3e-46 156.7 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_6 PF13405.6 OAG38332.1 - 0.0059 16.4 1.5 0.58 10.2 0.2 3.7 3 0 0 3 3 3 1 EF-hand domain GRAM PF02893.20 OAG38332.1 - 0.0093 15.8 0.0 0.023 14.6 0.0 1.7 1 1 0 1 1 1 1 GRAM domain GCIP PF13324.6 OAG38332.1 - 8.4 5.9 6.7 17 4.9 6.7 1.4 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Peptidase_C2 PF00648.21 OAG38333.1 - 4.2e-66 223.0 7.5 1.1e-64 218.4 7.5 2.3 1 1 0 1 1 1 1 Calpain family cysteine protease C2-C2_1 PF11618.8 OAG38333.1 - 0.15 12.1 0.1 0.27 11.3 0.1 1.3 1 0 0 1 1 1 0 First C2 domain of RPGR-interacting protein 1 ABC_membrane PF00664.23 OAG38334.1 - 5.3e-80 269.0 23.6 1.5e-40 139.6 7.0 2.8 2 1 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 OAG38334.1 - 9.1e-51 172.0 0.3 1.8e-29 103.0 0.0 2.9 3 0 0 3 3 3 2 ABC transporter SMC_N PF02463.19 OAG38334.1 - 6.2e-11 42.2 3.7 0.0015 18.0 0.1 4.4 2 2 1 4 4 4 3 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 OAG38334.1 - 5.2e-06 26.5 2.8 0.038 14.1 0.0 3.0 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_23 PF13476.6 OAG38334.1 - 2.5e-05 24.9 0.4 0.0019 18.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 OAG38334.1 - 3.7e-05 23.4 0.1 0.071 12.9 0.0 3.0 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 OAG38334.1 - 4e-05 23.6 0.2 0.019 14.8 0.0 3.1 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 OAG38334.1 - 7.6e-05 22.7 0.2 0.038 13.9 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 OAG38334.1 - 0.00012 22.6 0.6 0.12 12.7 0.3 2.6 2 0 0 2 2 2 2 AAA ATPase domain Dynamin_N PF00350.23 OAG38334.1 - 0.0017 18.4 0.3 0.28 11.2 0.0 2.6 2 0 0 2 2 2 1 Dynamin family AAA_27 PF13514.6 OAG38334.1 - 0.0086 15.7 0.1 0.046 13.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 OAG38334.1 - 0.01 16.2 0.0 0.59 10.6 0.0 2.9 2 0 0 2 2 2 0 RNA helicase AAA_15 PF13175.6 OAG38334.1 - 0.02 14.6 0.7 0.31 10.7 0.1 2.2 2 0 0 2 2 2 0 AAA ATPase domain DUF87 PF01935.17 OAG38334.1 - 0.025 14.7 0.8 2.2 8.3 0.0 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain IstB_IS21 PF01695.17 OAG38334.1 - 0.044 13.5 0.6 6.3 6.5 0.0 2.8 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_30 PF13604.6 OAG38334.1 - 0.048 13.4 1.7 0.72 9.5 0.0 2.8 2 1 0 2 2 2 0 AAA domain Roc PF08477.13 OAG38334.1 - 0.085 13.1 0.1 14 5.9 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 OAG38334.1 - 0.13 12.5 3.7 4.4 7.6 0.1 3.3 2 1 0 2 2 2 0 AAA domain GTP_EFTU PF00009.27 OAG38334.1 - 0.16 11.5 0.1 9.3 5.7 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain 60KD_IMP PF02096.20 OAG38334.1 - 3.8 7.4 8.4 0.73 9.7 3.8 2.1 2 0 0 2 2 2 0 60Kd inner membrane protein MWFE PF15879.5 OAG38334.1 - 8.1 6.7 5.5 8.8 6.6 0.2 3.2 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase MWFE subunit DUF2841 PF11001.8 OAG38335.1 - 8.2e-33 113.1 1.8 1.3e-32 112.4 1.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) DHR10 PF18595.1 OAG38335.1 - 2.3 8.3 5.3 3.9 7.6 5.3 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain SAC3_GANP PF03399.16 OAG38336.1 - 7e-94 314.5 0.0 1e-93 314.0 0.0 1.2 1 0 0 1 1 1 1 SAC3/GANP family PAM2 PF07145.15 OAG38336.1 - 0.072 12.8 0.6 0.32 10.8 0.6 2.2 1 0 0 1 1 1 0 Ataxin-2 C-terminal region DinB PF05163.12 OAG38336.1 - 5.7 6.8 5.4 1.1 9.1 0.4 2.3 2 0 0 2 2 2 0 DinB family Acyl-CoA_dh_1 PF00441.24 OAG38337.1 - 1.1e-27 97.1 0.9 2e-27 96.3 0.9 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 OAG38337.1 - 2.1e-18 66.3 0.0 3.6e-18 65.5 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 OAG38337.1 - 6.8e-15 55.7 0.0 1.7e-14 54.4 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 OAG38337.1 - 4e-12 46.6 0.7 4e-12 46.6 0.7 1.5 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Pkinase PF00069.25 OAG38338.1 - 9.7e-51 172.7 0.0 1.4e-50 172.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG38338.1 - 1e-29 103.6 0.0 1.5e-29 103.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAG38338.1 - 1.8e-12 47.2 0.0 1.2e-09 38.0 0.0 3.0 2 1 1 3 3 3 2 Kinase-like Kdo PF06293.14 OAG38338.1 - 0.00092 18.6 0.0 0.0019 17.6 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PIP49_C PF12260.8 OAG38338.1 - 0.12 12.0 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 PLDc_2 PF13091.6 OAG38339.1 - 2.1e-12 47.1 0.0 5.4e-06 26.3 0.0 3.2 3 0 0 3 3 3 2 PLD-like domain PLDc PF00614.22 OAG38339.1 - 1.8e-06 27.8 0.3 0.088 13.0 0.0 3.4 3 1 0 3 3 3 2 Phospholipase D Active site motif Sigma54_AID PF00309.20 OAG38339.1 - 0.65 9.9 2.7 1.3 8.9 2.7 1.5 1 0 0 1 1 1 0 Sigma-54 factor, Activator interacting domain (AID) Sad1_UNC PF07738.13 OAG38340.1 - 1e-32 112.9 0.1 1.7e-32 112.2 0.1 1.4 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Sugar_tr PF00083.24 OAG38341.1 - 1.5e-85 287.8 31.3 1.7e-85 287.6 31.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG38341.1 - 7.4e-17 61.3 37.3 7.4e-17 61.3 37.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 OAG38341.1 - 0.00025 19.7 7.1 0.00025 19.7 7.1 3.2 2 2 0 3 3 3 1 MFS/sugar transport protein DUF4131 PF13567.6 OAG38341.1 - 0.5 10.0 7.5 3.2 7.4 3.3 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) Abhydrolase_3 PF07859.13 OAG38342.1 - 1.9e-49 168.4 0.1 2.7e-49 167.9 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OAG38342.1 - 0.00011 21.7 0.1 0.0096 15.4 0.1 2.2 1 1 0 2 2 2 2 Prolyl oligopeptidase family COesterase PF00135.28 OAG38342.1 - 0.00031 19.7 0.2 0.002 17.0 0.2 1.9 1 1 0 1 1 1 1 Carboxylesterase family AXE1 PF05448.12 OAG38342.1 - 0.013 14.2 0.1 0.02 13.6 0.1 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) DLH PF01738.18 OAG38342.1 - 0.12 11.9 0.2 1.3 8.6 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family MFS_1 PF07690.16 OAG38344.1 - 8.9e-34 117.0 39.8 8.9e-34 117.0 39.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 OAG38344.1 - 0.048 11.9 5.5 1.6 6.9 2.9 2.4 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family MMR_HSR1 PF01926.23 OAG38345.1 - 4.8e-17 62.1 0.3 5.5e-15 55.5 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OAG38345.1 - 3.7e-08 33.5 0.5 0.00052 19.9 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 OAG38345.1 - 7e-08 32.2 0.1 1.2e-05 24.9 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B Dynamin_N PF00350.23 OAG38345.1 - 0.00027 21.0 2.9 0.052 13.6 0.3 3.3 3 1 0 3 3 3 2 Dynamin family AIG1 PF04548.16 OAG38345.1 - 0.0029 16.9 0.1 0.01 15.2 0.1 1.9 1 0 0 1 1 1 1 AIG1 family cobW PF02492.19 OAG38345.1 - 0.044 13.4 0.3 0.22 11.1 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 OAG38345.1 - 0.063 12.3 0.1 0.53 9.2 0.0 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB LTV PF04180.14 OAG38346.1 - 3.1e-113 379.4 11.3 3.5e-113 379.2 11.3 1.0 1 0 0 1 1 1 1 Low temperature viability protein NDUFA12 PF05071.16 OAG38347.1 - 9.2e-32 109.8 1.0 1.1e-31 109.5 1.0 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 UCH_1 PF13423.6 OAG38348.1 - 2.4e-12 47.1 0.0 1.6e-06 28.0 0.0 2.6 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Beta-lactamase PF00144.24 OAG38349.1 - 1.6e-45 155.8 0.0 4e-45 154.5 0.0 1.5 1 1 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.20 OAG38349.1 - 0.043 13.3 0.0 0.065 12.7 0.0 1.2 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase Ribosomal_L5_C PF00673.21 OAG38350.1 - 2.3e-28 98.2 0.0 3.6e-28 97.6 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 OAG38350.1 - 5.3e-06 26.7 0.0 9.2e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L5 EST1_DNA_bind PF10373.9 OAG38351.1 - 3.1e-42 145.0 0.1 9.3e-42 143.4 0.0 1.8 2 0 0 2 2 2 1 Est1 DNA/RNA binding domain EST1 PF10374.9 OAG38351.1 - 5.5e-22 78.9 2.4 6.9e-22 78.6 0.4 2.2 3 0 0 3 3 3 1 Telomerase activating protein Est1 TPR_17 PF13431.6 OAG38351.1 - 0.0043 17.3 0.1 0.013 15.9 0.1 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat PfkB PF00294.24 OAG38352.1 - 4e-63 213.5 0.0 4.5e-63 213.4 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 OAG38352.1 - 0.014 14.8 0.0 0.028 13.8 0.0 1.4 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase DUF1770 PF08589.10 OAG38353.1 - 8e-31 106.9 2.3 1.2e-30 106.4 2.3 1.2 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1770) Ribosomal_L24e PF01246.20 OAG38354.1 - 2.2e-27 95.1 0.3 2.2e-27 95.1 0.3 1.8 2 0 0 2 2 2 1 Ribosomal protein L24e DUF775 PF05603.12 OAG38354.1 - 0.17 11.4 1.7 0.21 11.1 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF775) UQ_con PF00179.26 OAG38356.1 - 3.5e-48 162.8 0.0 3.9e-48 162.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OAG38356.1 - 0.00074 19.2 0.0 0.001 18.8 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 OAG38356.1 - 0.016 15.1 0.1 0.03 14.2 0.1 1.5 1 1 0 1 1 1 0 UEV domain RWD PF05773.22 OAG38356.1 - 0.06 13.6 0.2 0.083 13.2 0.2 1.5 1 1 0 1 1 1 0 RWD domain FAD_binding_3 PF01494.19 OAG38357.1 - 2e-40 139.1 0.0 6e-40 137.6 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain WD40 PF00400.32 OAG38358.1 - 8.8e-06 26.4 17.3 0.0016 19.2 0.2 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat Zn_ribbon_17 PF17120.5 OAG38358.1 - 0.0091 15.6 5.4 0.029 14.0 3.4 2.3 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type COesterase PF00135.28 OAG38359.1 - 9.9e-85 285.3 0.0 1.3e-84 284.9 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family MFS_1 PF07690.16 OAG38360.1 - 5.3e-21 74.9 38.6 1.8e-20 73.2 24.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG38360.1 - 3.7e-17 62.3 15.5 4.8e-17 62.0 15.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Ni_hydr_CYTB PF01292.20 OAG38360.1 - 0.012 15.3 0.4 0.012 15.3 0.4 2.6 1 1 1 2 2 2 0 Prokaryotic cytochrome b561 DUF4405 PF14358.6 OAG38360.1 - 0.058 13.9 8.0 0.072 13.7 0.7 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4405) BLACT_WH PF17778.1 OAG38360.1 - 0.21 11.6 0.4 0.86 9.6 0.0 2.0 2 0 0 2 2 2 0 Beta-lactamase associated winged helix domain TauD PF02668.16 OAG38361.1 - 2.5e-55 188.2 2.0 3.5e-55 187.7 2.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Sugar_tr PF00083.24 OAG38362.1 - 6.2e-45 153.9 34.1 2.1e-43 148.8 34.1 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG38362.1 - 3.1e-10 39.5 42.4 4e-10 39.2 41.1 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Pet127 PF08634.10 OAG38363.1 - 1.2e-113 379.1 0.1 1.6e-113 378.7 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial protein Pet127 DNA_pol_phi PF04931.13 OAG38363.1 - 0.38 8.8 2.5 0.54 8.3 2.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi adh_short PF00106.25 OAG38364.1 - 6.4e-26 91.0 0.1 3.6e-25 88.6 0.1 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG38364.1 - 1.2e-15 57.7 0.0 1.8e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 OAG38364.1 - 6.5e-09 35.9 0.1 8e-09 35.7 0.1 1.1 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAG38364.1 - 1e-07 31.7 0.0 1.3e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 OAG38364.1 - 0.00018 21.5 0.2 0.0014 18.6 0.2 2.1 1 1 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 OAG38364.1 - 0.18 11.1 0.0 0.47 9.8 0.0 1.7 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase GARS_A PF01071.19 OAG38365.1 - 1.8e-82 275.9 0.0 3.1e-82 275.1 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain AIRS_C PF02769.22 OAG38365.1 - 7.6e-36 123.6 0.2 1.7e-35 122.5 0.2 1.6 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_N PF02844.15 OAG38365.1 - 1.8e-33 115.2 0.1 7.2e-33 113.2 0.1 2.2 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.16 OAG38365.1 - 2.1e-25 88.8 0.4 5.7e-25 87.4 0.4 1.8 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.24 OAG38365.1 - 2.7e-13 50.4 2.7 6.4e-13 49.2 1.7 2.2 2 0 0 2 2 1 1 AIR synthase related protein, N-terminal domain ATP-grasp_3 PF02655.14 OAG38365.1 - 4.7e-05 23.5 0.0 0.00018 21.6 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp PF02222.22 OAG38365.1 - 9.5e-05 22.0 0.0 0.00017 21.2 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 OAG38365.1 - 0.00051 19.7 0.0 0.0045 16.6 0.0 2.2 2 0 0 2 2 2 1 RimK-like ATP-grasp domain ATPgrasp_ST PF14397.6 OAG38365.1 - 0.0016 17.7 0.0 0.03 13.6 0.0 2.2 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp ATP-grasp_4 PF13535.6 OAG38365.1 - 0.028 14.0 0.0 0.057 13.0 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain CPSase_L_D2 PF02786.17 OAG38365.1 - 0.028 13.9 0.0 0.067 12.7 0.0 1.6 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_2 PF08442.10 OAG38365.1 - 0.053 13.1 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain GCV_T_C PF08669.11 OAG38365.1 - 0.091 12.7 0.2 0.87 9.6 0.0 2.5 2 0 0 2 2 2 0 Glycine cleavage T-protein C-terminal barrel domain GHMP_kinases_N PF00288.26 OAG38366.1 - 4.9e-11 42.7 0.2 9.3e-11 41.8 0.2 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 OAG38366.1 - 0.00045 20.5 0.0 0.00089 19.6 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal Actin PF00022.19 OAG38367.1 - 6.6e-144 479.5 0.0 2.7e-143 477.5 0.0 1.7 1 1 0 1 1 1 1 Actin Fes1 PF08609.10 OAG38368.1 - 2.2e-29 102.2 0.9 1.1e-26 93.6 0.3 2.7 3 0 0 3 3 3 2 Nucleotide exchange factor Fes1 HEAT_2 PF13646.6 OAG38368.1 - 5.2e-06 26.8 2.7 2.1e-05 24.8 1.0 2.5 2 2 0 2 2 2 1 HEAT repeats HEAT PF02985.22 OAG38368.1 - 1.4e-05 24.9 0.7 0.12 12.7 0.1 3.3 3 0 0 3 3 3 2 HEAT repeat HEAT_EZ PF13513.6 OAG38368.1 - 7.5e-05 23.1 1.1 0.00031 21.2 1.1 2.2 1 0 0 1 1 1 1 HEAT-like repeat Arm PF00514.23 OAG38368.1 - 0.00055 19.9 1.3 0.12 12.5 0.1 3.1 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat UPF0220 PF05255.11 OAG38369.1 - 9e-73 243.3 6.6 1e-72 243.1 6.6 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) Vps55 PF04133.14 OAG38370.1 - 4.6e-41 139.5 9.3 5.1e-41 139.3 9.3 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 DUF4349 PF14257.6 OAG38370.1 - 1.2 8.5 4.9 0.22 10.9 1.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4349) Proteasome PF00227.26 OAG38371.1 - 7.2e-50 169.1 0.1 9e-50 168.8 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 OAG38371.1 - 4.9e-12 45.3 0.3 4.9e-12 45.3 0.3 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature UPF0113 PF03657.13 OAG38371.1 - 0.06 13.6 0.1 8.8 6.7 0.0 2.8 3 0 0 3 3 3 0 UPF0113 PUA domain Lysine_decarbox PF03641.14 OAG38372.1 - 6.4e-31 107.2 0.1 1.2e-30 106.3 0.1 1.4 1 1 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 OAG38372.1 - 0.00014 21.5 0.0 0.0035 16.9 0.0 2.2 2 0 0 2 2 2 1 SLOG cluster4 family RNA_pol_I_A49 PF06870.12 OAG38372.1 - 0.098 11.5 0.0 0.12 11.2 0.0 1.1 1 0 0 1 1 1 0 A49-like RNA polymerase I associated factor DAGK_cat PF00781.24 OAG38372.1 - 0.13 11.9 0.0 2.2 7.9 0.0 2.2 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain SKG6 PF08693.10 OAG38373.1 - 0.0028 17.0 0.6 0.0069 15.8 0.6 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain NUDIX PF00293.28 OAG38375.1 - 2.1e-14 53.7 0.1 7.7e-14 51.9 0.0 1.7 2 0 0 2 2 2 1 NUDIX domain Glycos_transf_2 PF00535.26 OAG38376.1 - 4.5e-23 81.9 0.0 1.5e-21 76.9 0.0 2.7 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 OAG38376.1 - 3.8e-05 23.7 0.0 0.072 13.0 0.0 2.6 3 0 0 3 3 3 2 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 OAG38376.1 - 0.014 14.9 0.0 4.8 6.6 0.0 2.2 2 0 0 2 2 2 0 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 OAG38376.1 - 0.046 14.2 0.0 0.11 13.0 0.0 1.6 1 1 0 1 1 1 0 Glycosyl transferase family 2 SLC3A2_N PF16028.5 OAG38376.1 - 0.45 10.1 3.1 0.31 10.6 0.4 2.0 2 0 0 2 2 2 0 Solute carrier family 3 member 2 N-terminus Peroxin-3 PF04882.12 OAG38377.1 - 1.6e-156 522.0 0.0 1.9e-156 521.7 0.0 1.0 1 0 0 1 1 1 1 Peroxin-3 TB2_DP1_HVA22 PF03134.19 OAG38378.1 - 3.4e-27 94.2 9.3 3.4e-27 94.2 9.3 1.5 2 0 0 2 2 2 1 TB2/DP1, HVA22 family DUF5592 PF17332.2 OAG38378.1 - 3.5 8.3 7.6 0.49 11.0 2.8 1.9 1 1 1 2 2 2 0 Family of unknown function (DUF5592) RFX_DNA_binding PF02257.15 OAG38379.1 - 1.3e-27 96.2 0.1 3.1e-27 95.0 0.1 1.6 1 0 0 1 1 1 1 RFX DNA-binding domain Herpes_ori_bp PF02399.15 OAG38379.1 - 0.036 12.1 0.0 0.057 11.5 0.0 1.2 1 0 0 1 1 1 0 Origin of replication binding protein Spermine_synth PF01564.17 OAG38380.1 - 3.5e-05 23.3 0.0 5.6e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Methyltransf_23 PF13489.6 OAG38380.1 - 0.053 13.4 0.0 0.096 12.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_30 PF05430.11 OAG38380.1 - 0.089 12.7 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase ILVD_EDD PF00920.21 OAG38381.1 - 4.1e-154 514.0 0.0 4.9e-154 513.8 0.0 1.1 1 0 0 1 1 1 1 Dehydratase family Tcp11 PF05794.13 OAG38382.1 - 4.5e-94 316.0 1.9 6.3e-94 315.6 1.9 1.1 1 0 0 1 1 1 1 T-complex protein 11 ADH_zinc_N PF00107.26 OAG38383.1 - 9.5e-08 32.1 0.4 1.8e-07 31.2 0.4 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG38383.1 - 9.8e-06 25.4 0.0 1.8e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 OAG38383.1 - 0.11 12.4 0.0 0.27 11.2 0.0 1.7 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase Biotin_lipoyl PF00364.22 OAG38384.1 - 8.6e-22 76.8 0.4 1.6e-21 75.9 0.4 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 OAG38384.1 - 1.7e-08 34.6 0.1 8.9e-08 32.3 0.1 2.3 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 OAG38384.1 - 9e-05 22.2 0.0 0.0013 18.5 0.0 2.6 2 1 0 2 2 2 1 Biotin-lipoyl like HlyD_3 PF13437.6 OAG38384.1 - 0.051 14.3 0.5 1.5 9.6 0.0 2.9 2 1 1 3 3 3 0 HlyD family secretion protein WD40 PF00400.32 OAG38385.1 - 3.6e-23 81.4 13.4 0.00016 22.4 0.1 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG38385.1 - 7.2e-14 51.9 3.8 1.3e-05 25.4 0.1 4.1 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OAG38385.1 - 4.9e-06 26.5 0.1 0.084 12.7 0.0 3.1 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 OAG38385.1 - 0.0075 15.3 0.0 0.03 13.3 0.0 1.9 2 0 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PALB2_WD40 PF16756.5 OAG38385.1 - 0.18 10.7 1.0 13 4.6 0.1 2.3 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain Peptidase_M18 PF02127.15 OAG38386.1 - 3.3e-165 550.1 0.0 5.9e-165 549.3 0.0 1.4 1 1 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Hydrolase_6 PF13344.6 OAG38387.1 - 7.8e-31 106.2 0.0 1.3e-30 105.5 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OAG38387.1 - 2.5e-15 56.3 0.1 5.4e-15 55.2 0.1 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 OAG38387.1 - 8.1e-12 45.9 0.0 0.00018 21.9 0.0 2.3 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 OAG38387.1 - 1.2e-05 25.4 0.0 0.025 14.6 0.0 2.2 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase PNK3P PF08645.11 OAG38387.1 - 0.039 13.6 0.0 1.5 8.5 0.0 2.3 2 0 0 2 2 2 0 Polynucleotide kinase 3 phosphatase Acid_phosphat_B PF03767.14 OAG38387.1 - 0.072 12.7 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) Glyco_hydro_cc PF11790.8 OAG38388.1 - 3.7e-45 154.4 0.0 4e-45 154.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core DUF2838 PF10998.8 OAG38390.1 - 1.9e-42 144.0 11.0 1.9e-42 144.0 11.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2838) OmpH PF03938.14 OAG38390.1 - 0.037 14.4 2.4 0.038 14.3 0.7 1.7 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Curto_V3 PF07436.11 OAG38390.1 - 0.061 13.7 0.0 0.19 12.1 0.0 1.8 1 0 0 1 1 1 0 Curtovirus V3 protein SMC_N PF02463.19 OAG38391.1 - 9.2e-59 198.5 0.0 6.7e-58 195.7 0.0 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 OAG38391.1 - 2.5e-29 102.0 0.0 1.3e-28 99.7 0.0 2.3 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 OAG38391.1 - 6.7e-13 49.1 9.3 1.6e-06 28.2 0.0 4.0 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 OAG38391.1 - 7.2e-12 45.7 5.6 7.2e-12 45.7 5.6 4.6 3 3 1 4 4 3 1 AAA ATPase domain AAA_23 PF13476.6 OAG38391.1 - 5.5e-10 40.1 22.6 5.5e-10 40.1 22.6 6.2 3 2 2 5 5 3 2 AAA domain AAA_29 PF13555.6 OAG38391.1 - 8.7e-09 35.0 0.0 1.8e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Spc7 PF08317.11 OAG38391.1 - 0.00039 19.4 11.3 0.00039 19.4 11.3 6.3 4 2 2 6 6 6 3 Spc7 kinetochore protein SbcCD_C PF13558.6 OAG38391.1 - 0.0023 18.1 0.0 0.013 15.7 0.0 2.4 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit DUF724 PF05266.14 OAG38391.1 - 0.006 16.4 4.2 0.006 16.4 4.2 7.9 5 2 4 9 9 9 2 Protein of unknown function (DUF724) ABC_tran PF00005.27 OAG38391.1 - 0.37 11.3 0.1 0.37 11.3 0.1 6.0 4 2 0 4 4 2 0 ABC transporter Baculo_PEP_C PF04513.12 OAG38391.1 - 1.7 8.7 28.8 0.54 10.3 1.1 6.4 5 3 3 8 8 8 0 Baculovirus polyhedron envelope protein, PEP, C terminus GAIN_A PF18619.1 OAG38391.1 - 1.7 8.9 6.7 0.86 9.9 0.2 3.4 3 0 0 3 3 3 0 GPCR-Autoproteolysis-INducing (GAIN) subdomain A DUF3037 PF11236.8 OAG38391.1 - 5.8 7.4 29.0 0.19 12.2 5.1 6.2 3 2 2 5 5 5 0 Protein of unknown function (DUF3037) LETM1 PF07766.13 OAG38392.1 - 1e-105 352.9 0.7 1e-105 352.9 0.7 2.1 2 0 0 2 2 2 1 LETM1-like protein SAP PF02037.27 OAG38392.1 - 4.9e-05 23.0 1.0 0.0029 17.3 0.0 3.7 4 0 0 4 4 4 1 SAP domain ASD2 PF08687.11 OAG38392.1 - 8.6 5.8 27.4 0.31 10.5 7.2 2.6 2 0 0 2 2 2 0 Apx/Shroom domain ASD2 PWI PF01480.17 OAG38393.1 - 2.1e-31 108.0 0.1 3.5e-31 107.3 0.1 1.4 1 0 0 1 1 1 1 PWI domain CSD2 PF17876.1 OAG38393.1 - 0.094 12.9 0.0 0.26 11.5 0.0 1.7 1 0 0 1 1 1 0 Cold shock domain zf-C2H2 PF00096.26 OAG38395.1 - 0.0003 21.1 20.6 0.014 15.9 1.7 4.9 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OAG38395.1 - 0.067 13.7 0.3 0.067 13.7 0.3 3.1 4 0 0 4 4 4 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 OAG38395.1 - 0.34 11.9 20.1 0.48 11.4 1.8 4.7 4 0 0 4 4 4 0 C2H2-type zinc finger zf-CHCC PF10276.9 OAG38395.1 - 0.47 10.6 4.9 11 6.2 0.5 2.4 2 0 0 2 2 2 0 Zinc-finger domain zf-C2H2_jaz PF12171.8 OAG38395.1 - 3.8 7.9 13.5 0.15 12.4 3.9 3.1 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding DSPc PF00782.20 OAG38396.1 - 1.1e-05 25.3 0.0 1.3e-05 25.0 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain DSPc PF00782.20 OAG38397.1 - 0.011 15.6 0.0 0.018 14.9 0.0 1.3 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Vfa1 PF08432.10 OAG38398.1 - 2.6e-58 197.3 15.6 3e-58 197.2 15.6 1.0 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 Sec16 PF12932.7 OAG38398.1 - 0.013 16.1 0.6 0.025 15.2 0.6 1.6 1 0 0 1 1 1 0 Vesicle coat trafficking protein Sec16 mid-region DUF5093 PF17011.5 OAG38398.1 - 0.033 14.5 4.8 0.056 13.7 4.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5093) U79_P34 PF03064.16 OAG38398.1 - 0.045 13.1 11.8 0.053 12.9 11.8 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Rrn6 PF10214.9 OAG38398.1 - 0.048 12.2 3.8 0.052 12.0 3.8 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor RXT2_N PF08595.11 OAG38398.1 - 0.083 12.9 8.0 0.11 12.5 8.0 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal PPL5 PF18168.1 OAG38398.1 - 0.15 11.3 8.9 0.18 11.1 8.9 1.1 1 0 0 1 1 1 0 Prim-pol family 5 DUF913 PF06025.12 OAG38398.1 - 0.38 9.7 2.3 0.44 9.5 2.3 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) GNAT_acetyltr_2 PF13718.6 OAG38398.1 - 0.44 9.9 2.5 0.57 9.5 2.5 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase 2 Connexin PF00029.19 OAG38398.1 - 0.57 9.9 4.0 0.75 9.5 4.0 1.3 1 0 0 1 1 1 0 Connexin FAM176 PF14851.6 OAG38398.1 - 2.9 7.5 8.5 3.9 7.1 8.5 1.4 1 0 0 1 1 1 0 FAM176 family Paramyxo_ncap PF00973.19 OAG38398.1 - 5.1 5.9 7.3 6.4 5.6 7.3 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein MRP-S25 PF13741.6 OAG38399.1 - 1.7e-72 243.7 0.8 2.1e-72 243.4 0.8 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.9 OAG38399.1 - 0.022 15.0 3.6 2.8 8.2 0.1 3.1 3 1 0 3 3 3 0 Mitochondrial ribosomal protein S23 PPR_2 PF13041.6 OAG38400.1 - 2.3e-10 40.5 1.5 0.072 13.3 0.0 5.1 4 1 1 5 5 5 4 PPR repeat family PPR PF01535.20 OAG38400.1 - 4.1e-05 23.5 0.5 0.11 12.7 0.0 4.1 4 0 0 4 4 4 2 PPR repeat PPR_3 PF13812.6 OAG38400.1 - 0.0024 17.9 0.3 0.53 10.4 0.0 3.1 4 0 0 4 4 4 1 Pentatricopeptide repeat domain PPR_long PF17177.4 OAG38400.1 - 0.007 15.7 0.2 0.02 14.3 0.0 1.8 2 0 0 2 2 2 1 Pentacotripeptide-repeat region of PRORP FMN_dh PF01070.18 OAG38401.1 - 1.1e-107 360.1 0.0 1.3e-107 359.8 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 OAG38401.1 - 8.2e-18 64.3 0.0 1.6e-17 63.4 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 OAG38401.1 - 0.00025 20.3 0.1 0.00041 19.6 0.1 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase TatD_DNase PF01026.21 OAG38402.1 - 2.6e-51 174.4 0.0 3.1e-51 174.2 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase Y_phosphatase2 PF03162.13 OAG38403.1 - 4.1e-40 137.1 0.0 5.8e-40 136.6 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 OAG38403.1 - 4.2e-08 33.4 0.0 1.1e-07 32.1 0.0 1.7 1 1 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 OAG38403.1 - 0.00032 20.5 0.0 0.00043 20.1 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 OAG38403.1 - 0.12 11.9 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase PDZ_1 PF12812.7 OAG38404.1 - 5.3e-46 154.5 0.2 1.2e-28 99.0 0.0 3.4 3 0 0 3 3 3 2 PDZ-like domain Trypsin_2 PF13365.6 OAG38404.1 - 2.8e-25 90.0 2.3 1.8e-21 77.6 0.1 3.2 3 0 0 3 3 3 2 Trypsin-like peptidase domain PDZ_6 PF17820.1 OAG38404.1 - 2.2e-14 53.0 1.5 5e-08 32.7 0.2 3.8 3 0 0 3 3 3 3 PDZ domain PDZ_2 PF13180.6 OAG38404.1 - 2.7e-14 53.2 6.1 5e-06 26.7 0.1 4.8 5 0 0 5 5 5 3 PDZ domain PDZ PF00595.24 OAG38404.1 - 1e-10 41.8 0.1 0.0001 22.6 0.0 3.8 4 0 0 4 4 4 3 PDZ domain Tricorn_PDZ PF14685.6 OAG38404.1 - 0.015 15.3 1.7 6.7 6.8 0.1 3.8 4 0 0 4 4 4 0 Tricorn protease PDZ domain Peptidase_S46 PF10459.9 OAG38404.1 - 0.068 11.8 0.2 0.12 11.0 0.2 1.3 1 0 0 1 1 1 0 Peptidase S46 AMP-binding PF00501.28 OAG38405.1 - 7e-69 232.4 0.0 9.1e-69 232.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG38405.1 - 0.00014 22.8 0.0 0.00032 21.6 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DAO PF01266.24 OAG38406.1 - 4.1e-38 131.9 0.0 4.7e-38 131.7 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 OAG38406.1 - 1.7e-06 28.1 0.3 0.049 13.6 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 OAG38406.1 - 8.6e-06 25.9 0.0 2e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 OAG38406.1 - 1.2e-05 24.6 0.1 0.00052 19.2 0.1 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 OAG38406.1 - 0.00012 21.4 0.1 0.0011 18.2 0.1 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 OAG38406.1 - 0.0054 15.6 0.0 1.7 7.4 0.0 2.1 2 0 0 2 2 2 2 Tryptophan halogenase K_oxygenase PF13434.6 OAG38406.1 - 0.056 12.6 0.0 0.42 9.7 0.0 2.0 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Pyridox_oxase_2 PF12766.7 OAG38407.1 - 1.4e-25 89.8 0.0 2.3e-25 89.1 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Ctr PF04145.15 OAG38408.1 - 1.5e-28 100.3 0.0 1.8e-28 100.0 0.0 1.1 1 0 0 1 1 1 1 Ctr copper transporter family adh_short PF00106.25 OAG38409.1 - 3.6e-26 91.8 0.2 1.5e-24 86.5 0.2 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG38409.1 - 7.3e-12 45.3 0.1 1.8e-10 40.8 0.1 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG38409.1 - 1.6e-10 41.2 0.1 2.8e-10 40.4 0.1 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OAG38409.1 - 0.00014 21.1 0.0 0.00035 19.8 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 OAG38409.1 - 0.00097 18.7 0.0 0.0015 18.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 OAG38409.1 - 0.025 14.8 0.0 0.06 13.6 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 OAG38410.1 - 7.3e-18 64.9 0.0 1.1e-17 64.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 OAG38410.1 - 5.1e-10 39.0 0.0 1.9e-09 37.1 0.0 1.8 2 0 0 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.19 OAG38410.1 - 4.3e-08 32.5 0.0 8.2e-08 31.6 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 OAG38410.1 - 1.2e-06 28.1 0.3 5e-06 26.2 0.3 1.9 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 OAG38410.1 - 0.046 13.2 0.3 5.5 6.4 0.1 2.2 2 0 0 2 2 2 0 short chain dehydrogenase KR PF08659.10 OAG38410.1 - 0.053 13.4 0.2 0.15 12.0 0.2 1.6 1 1 0 1 1 1 0 KR domain NmrA PF05368.13 OAG38410.1 - 0.077 12.5 0.1 8.1 5.9 0.1 2.6 3 0 0 3 3 3 0 NmrA-like family Fungal_trans_2 PF11951.8 OAG38411.1 - 3.2e-57 194.1 0.2 5.4e-57 193.3 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain NicO PF03824.16 OAG38412.1 - 0.12 11.6 1.2 0.15 11.4 1.2 1.1 1 0 0 1 1 1 0 High-affinity nickel-transport protein EutQ PF06249.12 OAG38413.1 - 4.3e-10 39.6 0.0 5.3e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Cupin_3 PF05899.12 OAG38413.1 - 6.2e-09 35.4 0.0 9e-09 34.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_2 PF07883.11 OAG38413.1 - 0.00038 20.1 0.1 0.00053 19.7 0.1 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 OAG38413.1 - 0.024 14.2 0.0 0.038 13.6 0.0 1.3 1 0 0 1 1 1 0 Cupin Abhydrolase_2 PF02230.16 OAG38414.1 - 1.7e-60 204.5 0.0 2.1e-60 204.2 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 OAG38414.1 - 3.3e-07 29.8 0.3 0.0023 17.2 0.0 3.1 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 OAG38414.1 - 1.6e-05 24.5 0.2 0.00034 20.2 0.0 2.3 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 OAG38414.1 - 0.00024 21.8 0.0 0.00059 20.5 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.13 OAG38414.1 - 0.0026 17.4 0.0 0.013 15.2 0.0 2.1 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.20 OAG38414.1 - 0.013 15.1 0.5 0.21 11.2 0.3 2.6 1 1 1 2 2 2 0 alpha/beta hydrolase fold DLH PF01738.18 OAG38414.1 - 0.015 14.8 0.0 0.021 14.4 0.0 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family DUF1581 PF07619.11 OAG38414.1 - 0.029 14.5 0.0 0.048 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1581) Ammonium_transp PF00909.21 OAG38414.1 - 0.057 12.1 0.1 0.083 11.6 0.1 1.1 1 0 0 1 1 1 0 Ammonium Transporter Family Abhydrolase_3 PF07859.13 OAG38414.1 - 0.06 13.2 0.1 3.1 7.6 0.0 2.2 1 1 1 2 2 2 0 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 OAG38414.1 - 0.065 12.8 0.1 0.86 9.2 0.0 2.1 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region Cutinase PF01083.22 OAG38414.1 - 0.23 11.4 0.0 0.4 10.6 0.0 1.3 1 0 0 1 1 1 0 Cutinase NAC PF01849.18 OAG38415.1 - 4.5e-24 84.2 0.4 1.1e-23 83.0 0.4 1.7 1 0 0 1 1 1 1 NAC domain FMO-like PF00743.19 OAG38417.1 - 1.5e-14 53.3 0.2 8.6e-13 47.5 0.2 2.6 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OAG38417.1 - 3.1e-09 36.9 0.0 2e-08 34.3 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 OAG38417.1 - 3.2e-05 23.2 0.1 0.00021 20.6 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 OAG38417.1 - 8.1e-05 22.0 0.0 0.33 10.1 0.0 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAG38417.1 - 0.00011 22.0 0.0 0.0015 18.2 0.0 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 OAG38417.1 - 0.016 14.5 0.0 1.1 8.4 0.0 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FB_lectin PF07367.11 OAG38417.1 - 0.036 14.0 0.2 0.036 14.0 0.2 2.5 4 0 0 4 4 4 0 Fungal fruit body lectin DUF4211 PF13926.6 OAG38417.1 - 0.1 12.6 0.4 14 5.7 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4211) Glyco_hydro_3_C PF01915.22 OAG38418.1 - 4e-43 147.8 0.0 9.3e-43 146.6 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 OAG38418.1 - 3.8e-39 134.9 0.0 5.6e-39 134.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 OAG38418.1 - 5.4e-22 77.7 0.1 1e-21 76.8 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain MmgE_PrpD PF03972.14 OAG38419.1 - 5.3e-144 480.0 0.0 6e-144 479.8 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family Pkinase PF00069.25 OAG38420.1 - 3.6e-59 200.3 0.0 3.6e-58 197.0 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG38420.1 - 1.2e-28 100.1 0.2 1.6e-19 70.2 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 OAG38420.1 - 3.2e-05 24.0 5.5 0.2 11.6 0.1 3.7 2 1 2 4 4 4 3 Phosphotransferase enzyme family Pkinase_C PF00433.24 OAG38420.1 - 0.00035 21.2 0.5 0.00035 21.2 0.5 2.2 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.6 OAG38420.1 - 0.0014 18.0 0.1 0.0085 15.4 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 OAG38420.1 - 0.025 13.5 0.0 0.054 12.4 0.0 1.5 1 1 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 OAG38420.1 - 0.057 12.8 0.0 0.14 11.5 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family LRR_4 PF12799.7 OAG38421.1 - 0.11 13.0 2.3 14 6.3 0.0 4.1 3 1 2 5 5 5 0 Leucine Rich repeats (2 copies) CarboxypepD_reg PF13620.6 OAG38422.1 - 0.14 12.5 0.5 0.37 11.1 0.5 1.7 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain Peptidase_M41 PF01434.18 OAG38423.1 - 4.4e-66 222.4 0.0 9.1e-66 221.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 OAG38423.1 - 3.8e-43 147.1 0.0 1.2e-42 145.5 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OAG38423.1 - 6.9e-12 45.0 0.1 1.9e-11 43.6 0.1 1.8 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 OAG38423.1 - 1.4e-07 31.8 0.0 3.5e-07 30.5 0.0 1.7 1 0 0 1 1 1 1 FtsH Extracellular AAA_5 PF07728.14 OAG38423.1 - 0.00048 20.1 0.0 0.0017 18.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OAG38423.1 - 0.0021 18.4 0.2 0.15 12.4 0.2 2.8 1 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 OAG38423.1 - 0.0029 17.3 0.0 0.045 13.5 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Phage_Gp15 PF06854.11 OAG38423.1 - 0.0033 17.4 0.2 0.0066 16.4 0.2 1.4 1 0 0 1 1 1 1 Bacteriophage Gp15 protein AAA_22 PF13401.6 OAG38423.1 - 0.009 16.3 0.7 1.1 9.5 0.1 3.5 4 0 0 4 4 4 1 AAA domain TIP49 PF06068.13 OAG38423.1 - 0.0093 15.2 0.0 0.016 14.4 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_17 PF13207.6 OAG38423.1 - 0.093 13.2 1.0 0.4 11.1 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_2 PF07724.14 OAG38423.1 - 0.14 12.2 1.1 0.35 11.0 0.0 2.2 2 1 0 2 2 2 0 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 OAG38423.1 - 0.2 11.4 0.3 0.41 10.3 0.0 1.7 2 0 0 2 2 1 0 IstB-like ATP binding protein AAA_28 PF13521.6 OAG38423.1 - 0.25 11.6 1.3 1.4 9.2 0.0 2.7 3 0 0 3 3 3 0 AAA domain TipAS PF07739.13 OAG38423.1 - 2.2 8.8 8.3 28 5.3 2.2 3.3 3 0 0 3 3 3 0 TipAS antibiotic-recognition domain TbpB_A PF17484.2 OAG38423.1 - 3.1 8.5 11.1 0.27 12.0 3.6 2.3 2 0 0 2 2 2 0 N-Lobe handle Tf-binding protein B Gcn1_N PF12074.8 OAG38424.1 - 6.1e-89 298.8 2.4 6.1e-89 298.8 2.4 3.7 6 0 0 6 6 6 1 Generalcontrol nonderepressible 1 (Gcn1) N-terminal HEAT PF02985.22 OAG38424.1 - 1.9e-30 102.3 42.3 0.018 15.3 0.0 23.8 25 0 0 25 25 24 7 HEAT repeat HEAT_EZ PF13513.6 OAG38424.1 - 2.6e-28 98.0 45.0 2.6e-07 31.0 0.0 19.6 15 5 7 22 22 20 9 HEAT-like repeat HEAT_2 PF13646.6 OAG38424.1 - 9.4e-27 93.2 62.5 2.6e-07 31.0 1.5 17.3 10 4 8 19 19 18 7 HEAT repeats Cnd1 PF12717.7 OAG38424.1 - 3.6e-16 59.6 3.9 0.03 14.3 0.1 10.3 8 2 2 10 10 10 3 non-SMC mitotic condensation complex subunit 1 ParcG PF10274.9 OAG38424.1 - 5.8e-12 46.1 0.9 0.00019 21.6 0.0 6.8 6 1 2 8 8 7 2 Parkin co-regulated protein CLASP_N PF12348.8 OAG38424.1 - 4e-11 42.9 0.0 0.7 9.4 0.0 7.3 5 1 2 8 8 8 4 CLASP N terminal Vac14_Fab1_bd PF12755.7 OAG38424.1 - 8.8e-11 42.3 0.0 1.7 9.3 0.0 8.2 7 2 1 8 8 8 3 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 OAG38424.1 - 9.1e-06 24.5 11.0 1.8 7.0 0.4 7.5 7 2 2 9 9 9 2 Adaptin N terminal region Cohesin_HEAT PF12765.7 OAG38424.1 - 0.00069 19.9 15.2 1.3 9.4 0.1 6.7 7 0 0 7 7 7 3 HEAT repeat associated with sister chromatid cohesion MMS19_C PF12460.8 OAG38424.1 - 0.0012 18.0 11.8 0.24 10.5 0.1 6.7 6 2 2 8 8 8 2 RNAPII transcription regulator C-terminal TFCD_C PF12612.8 OAG38424.1 - 0.0017 18.2 1.4 0.017 15.0 0.0 3.4 4 0 0 4 4 4 1 Tubulin folding cofactor D C terminal TIP120 PF08623.10 OAG38424.1 - 0.0023 17.7 0.9 1.1 9.0 0.0 4.9 5 1 1 6 6 6 1 TATA-binding protein interacting (TIP20) Ipi1_N PF12333.8 OAG38424.1 - 0.0067 17.0 0.1 0.4 11.3 0.1 3.9 3 0 0 3 3 3 1 Rix1 complex component involved in 60S ribosome maturation Vitellogenin_N PF01347.22 OAG38424.1 - 0.023 13.1 0.0 0.16 10.3 0.0 2.3 2 0 0 2 2 2 0 Lipoprotein amino terminal region Arm PF00514.23 OAG38424.1 - 0.031 14.3 8.1 24 5.2 0.1 8.0 9 0 0 9 9 8 0 Armadillo/beta-catenin-like repeat Tti2 PF10521.9 OAG38424.1 - 0.098 12.2 0.2 10 5.5 0.0 4.3 5 0 0 5 5 5 0 Tti2 family MitMem_reg PF13012.6 OAG38426.1 - 1.4e-07 31.9 0.2 4.6e-07 30.2 0.2 1.8 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 OAG38426.1 - 0.00028 20.8 0.0 0.00048 20.1 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Proteasom_PSMB PF10508.9 OAG38427.1 - 0.003 16.1 0.0 0.0043 15.6 0.0 1.2 1 0 0 1 1 1 1 Proteasome non-ATPase 26S subunit TrmO_C PF18389.1 OAG38427.1 - 0.12 12.5 0.9 1.7 8.8 0.1 2.9 3 0 0 3 3 3 0 TrmO C-terminal domain XPC-binding PF09280.11 OAG38427.1 - 2.8 7.7 5.8 7 6.5 2.2 2.6 2 0 0 2 2 2 0 XPC-binding domain adh_short_C2 PF13561.6 OAG38429.1 - 1.3e-60 204.9 0.1 1.5e-60 204.7 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG38429.1 - 1.7e-44 151.6 0.0 2.2e-44 151.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG38429.1 - 1.6e-10 41.2 0.6 2.5e-10 40.6 0.6 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 OAG38429.1 - 0.00035 20.5 0.0 0.00055 19.9 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_25 PF13649.6 OAG38429.1 - 0.0014 19.3 0.0 0.0029 18.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.21 OAG38429.1 - 0.0077 15.7 0.0 0.011 15.2 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 OAG38429.1 - 0.024 13.7 0.0 0.044 12.9 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 OAG38429.1 - 0.041 12.9 0.0 0.11 11.5 0.0 1.7 1 1 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 OAG38429.1 - 0.076 12.9 1.4 0.19 11.6 0.2 2.0 2 1 0 2 2 2 0 NAD(P)H-binding THF_DHG_CYH_C PF02882.19 OAG38429.1 - 0.099 12.0 0.0 0.23 10.8 0.0 1.6 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain UDPG_MGDP_dh_N PF03721.14 OAG38429.1 - 0.14 11.7 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_23 PF13489.6 OAG38429.1 - 0.16 11.8 0.0 0.42 10.4 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.12 OAG38429.1 - 0.17 12.7 0.0 0.41 11.4 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Gln-synt_C PF00120.24 OAG38430.1 - 7.9e-83 278.3 0.0 1e-82 278.0 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain SET PF00856.28 OAG38431.1 - 1.1e-18 68.1 0.5 2.9e-18 66.8 0.0 2.0 2 1 0 2 2 2 1 SET domain 2-Hacid_dh_C PF02826.19 OAG38432.1 - 5e-52 175.8 0.0 7.7e-52 175.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 OAG38432.1 - 3.4e-20 72.1 0.0 4.1e-20 71.8 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 OAG38432.1 - 0.0015 18.7 0.0 0.0024 18.1 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Fungal_trans PF04082.18 OAG38433.1 - 6.5e-21 74.5 0.1 9.8e-21 74.0 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain PhyH PF05721.13 OAG38434.1 - 4e-08 33.8 0.0 5.9e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 OAG38434.1 - 1.3e-06 27.5 0.1 0.015 14.1 0.0 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF1479) PHZA_PHZB PF03284.13 OAG38434.1 - 0.063 12.9 0.1 0.17 11.5 0.1 1.7 1 0 0 1 1 1 0 Phenazine biosynthesis protein A/B PsiA PF06952.11 OAG38434.1 - 0.074 12.3 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 PsiA protein Epimerase PF01370.21 OAG38435.1 - 9.7e-16 58.0 0.0 1.4e-15 57.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAG38435.1 - 1.8e-09 37.5 0.1 5.6e-06 26.0 0.0 2.1 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 OAG38435.1 - 3e-08 33.0 0.0 4.1e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 OAG38435.1 - 8.1e-06 25.2 0.0 0.022 13.9 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 OAG38435.1 - 1.4e-05 24.4 0.0 0.00013 21.2 0.0 2.0 1 1 0 1 1 1 1 RmlD substrate binding domain Ldh_1_N PF00056.23 OAG38435.1 - 0.026 14.6 0.0 0.052 13.6 0.0 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain F_bP_aldolase PF01116.20 OAG38436.1 - 1.1e-79 267.8 0.0 1.3e-79 267.7 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Ferric_reduct PF01794.19 OAG38437.1 - 1.9e-19 70.0 16.3 4.7e-19 68.7 16.3 1.7 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 OAG38437.1 - 2.9e-19 69.7 0.0 4.4e-19 69.1 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 OAG38437.1 - 5e-15 55.5 0.0 1e-14 54.6 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain HET PF06985.11 OAG38439.1 - 6.2e-33 114.2 0.0 1e-32 113.5 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) T5orf172 PF10544.9 OAG38440.1 - 5.2e-08 33.4 4.4 7.4e-08 32.9 0.0 2.7 3 0 0 3 3 3 1 T5orf172 domain MUG113 PF13455.6 OAG38440.1 - 0.026 15.2 0.4 0.09 13.5 0.0 2.0 2 0 0 2 2 2 0 Meiotically up-regulated gene 113 DUF4551 PF15087.6 OAG38440.1 - 0.4 9.4 2.4 0.71 8.6 2.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) TEA PF01285.18 OAG38441.1 - 4.1e-27 94.1 0.1 1e-26 92.8 0.1 1.7 1 0 0 1 1 1 1 TEA/ATTS domain RVP_2 PF08284.11 OAG38441.1 - 0.27 11.0 0.5 1.5 8.6 0.0 2.1 2 0 0 2 2 2 0 Retroviral aspartyl protease RRM_1 PF00076.22 OAG38442.1 - 2.3e-69 229.2 0.1 1.3e-17 63.4 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OAG38442.1 - 1.6e-05 24.7 0.0 0.07 13.0 0.0 4.7 5 0 0 5 5 5 1 Occluded RNA-recognition motif RRM_5 PF13893.6 OAG38442.1 - 4.2e-05 23.1 0.0 1.2 8.8 0.0 4.5 5 0 0 5 5 5 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OAG38442.1 - 0.0016 18.5 0.0 13 5.9 0.0 4.2 4 0 0 4 4 4 1 RNA recognition motif Limkain-b1 PF11608.8 OAG38442.1 - 0.0031 17.6 0.4 2.5 8.2 0.0 4.9 5 2 0 5 5 5 1 Limkain b1 Nup35_RRM_2 PF14605.6 OAG38442.1 - 0.0039 17.1 0.0 6.5 6.8 0.0 3.4 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif SET_assoc PF11767.8 OAG38442.1 - 0.027 14.1 0.0 32 4.3 0.0 4.0 4 0 0 4 4 4 0 Histone lysine methyltransferase SET associated RRM_Rrp7 PF17799.1 OAG38442.1 - 0.044 13.6 0.1 3.8 7.3 0.0 3.3 3 0 0 3 3 3 0 Rrp7 RRM-like N-terminal domain MmgE_PrpD PF03972.14 OAG38443.1 - 8.3e-70 235.5 2.3 1e-69 235.2 2.3 1.0 1 0 0 1 1 1 1 MmgE/PrpD family 2-oxoacid_dh PF00198.23 OAG38444.1 - 3.2e-68 229.7 0.3 4.2e-67 226.0 0.1 2.0 2 0 0 2 2 2 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 OAG38444.1 - 1.2e-18 66.6 0.7 3.7e-18 65.1 0.1 2.1 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.17 OAG38444.1 - 6.4e-15 55.2 0.2 1.3e-14 54.2 0.2 1.6 1 0 0 1 1 1 1 e3 binding domain E1_dh PF00676.20 OAG38445.1 - 3.5e-85 285.6 0.0 2.9e-84 282.6 0.0 1.9 1 1 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 OAG38445.1 - 7.2e-06 25.9 0.5 5.2e-05 23.1 0.4 2.1 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 OAG38445.1 - 0.001 18.4 0.0 0.0018 17.5 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Transket_pyr PF02779.24 OAG38446.1 - 4.3e-42 143.8 0.0 8e-42 142.9 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 OAG38446.1 - 2.9e-33 114.4 0.0 8.3e-33 112.9 0.0 1.7 2 0 0 2 2 2 1 Transketolase, C-terminal domain PFOR_II PF17147.4 OAG38446.1 - 0.07 13.4 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 Pyruvate:ferredoxin oxidoreductase core domain II Fungal_trans PF04082.18 OAG38447.1 - 3.1e-23 82.2 0.2 4.9e-23 81.5 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG38447.1 - 9e-07 28.9 11.4 9e-07 28.9 11.4 2.1 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_3 PF01494.19 OAG38448.1 - 8.5e-63 212.7 0.0 1.1e-62 212.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 OAG38448.1 - 9.5e-05 21.9 0.1 0.0089 15.4 0.2 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 OAG38448.1 - 0.00013 20.9 0.0 0.00019 20.3 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 OAG38448.1 - 0.00025 20.2 0.1 0.00043 19.5 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 OAG38448.1 - 0.00033 19.9 0.0 0.00063 18.9 0.0 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 OAG38448.1 - 0.00034 19.9 0.0 0.00063 19.1 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG38448.1 - 0.00054 20.1 0.1 0.0019 18.4 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 OAG38448.1 - 0.00061 19.1 0.0 0.0014 17.9 0.0 1.6 2 0 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.6 OAG38448.1 - 0.0018 17.6 0.0 0.0032 16.8 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 OAG38448.1 - 0.0039 16.1 0.0 0.011 14.7 0.0 1.7 2 0 0 2 2 2 1 Tryptophan halogenase DAO PF01266.24 OAG38448.1 - 0.0066 16.1 1.0 0.02 14.5 0.1 2.2 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 OAG38448.1 - 0.013 16.1 0.1 0.048 14.2 0.0 2.1 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OAG38448.1 - 0.09 11.8 1.2 0.23 10.4 1.2 1.8 1 1 0 1 1 1 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 OAG38448.1 - 0.13 11.5 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Aldedh PF00171.22 OAG38449.1 - 9e-136 453.0 0.4 1e-135 452.9 0.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 OAG38449.1 - 0.0046 16.4 0.0 0.0078 15.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1487) TRI12 PF06609.13 OAG38450.1 - 8.8e-21 73.9 16.4 1.2e-20 73.5 16.4 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG38450.1 - 1.9e-16 59.9 50.2 9.6e-15 54.3 45.7 3.0 2 1 0 2 2 2 2 Major Facilitator Superfamily Aa_trans PF01490.18 OAG38451.1 - 1.2e-32 113.1 33.4 1.2e-32 113.1 33.4 2.0 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein Pox_A14 PF05767.12 OAG38451.1 - 0.7 10.1 8.7 1.4 9.1 0.1 3.1 2 1 0 2 2 2 0 Poxvirus virion envelope protein A14 Pyr_redox_2 PF07992.14 OAG38452.1 - 1.4e-14 54.1 0.0 8.5e-10 38.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG38452.1 - 5.5e-14 52.1 0.0 1.7e-11 44.0 0.0 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 OAG38452.1 - 1.8e-10 39.8 0.0 1.6e-09 36.8 0.0 2.2 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OAG38452.1 - 1.5e-05 25.1 0.3 5.7e-05 23.3 0.2 2.1 1 1 1 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 OAG38452.1 - 2.2e-05 23.8 0.0 0.002 17.3 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Shikimate_DH PF01488.20 OAG38452.1 - 5e-05 23.4 0.0 0.032 14.3 0.0 2.4 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.24 OAG38452.1 - 9.5e-05 21.7 0.0 0.00036 19.8 0.0 2.0 3 0 0 3 3 3 1 FAD binding domain DAO PF01266.24 OAG38452.1 - 0.0013 18.4 0.6 0.19 11.2 0.2 2.6 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 OAG38452.1 - 0.0017 17.7 0.6 0.036 13.3 0.6 2.3 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.22 OAG38452.1 - 0.0061 15.7 0.1 9.1 5.2 0.0 3.0 3 0 0 3 3 3 2 Glucose inhibited division protein A mRNA_cap_C PF03919.15 OAG38452.1 - 0.051 14.2 0.3 0.43 11.2 0.0 2.3 2 0 0 2 2 2 0 mRNA capping enzyme, C-terminal domain ArAE_2_N PF10337.9 OAG38453.1 - 3.7e-37 128.5 10.1 5.1e-36 124.7 10.1 2.6 1 1 0 1 1 1 1 Putative ER transporter, 6TM, N-terminal FUSC_2 PF13515.6 OAG38453.1 - 5.9e-15 55.5 14.1 5.9e-15 55.5 14.1 3.4 3 1 0 3 3 3 1 Fusaric acid resistance protein-like ArAE_2 PF10334.9 OAG38453.1 - 1.9e-06 27.9 0.1 0.1 12.4 0.0 2.8 3 1 0 3 3 3 2 Aromatic acid exporter family member 2 Phage_Gp17 PF17549.2 OAG38453.1 - 0.11 12.6 0.1 0.19 11.7 0.1 1.3 1 0 0 1 1 1 0 Gene Product 17 CorA PF01544.18 OAG38454.1 - 0.00012 21.5 3.2 0.00043 19.7 3.3 1.9 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF2207 PF09972.9 OAG38454.1 - 0.00044 19.1 0.1 0.00064 18.6 0.1 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) Ank_2 PF12796.7 OAG38454.1 - 0.0027 18.3 0.0 0.0072 16.9 0.0 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAG38454.1 - 0.016 15.8 0.0 0.14 12.8 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Cytochrom_B562 PF07361.11 OAG38454.1 - 0.19 12.4 4.5 4.4 8.0 1.5 2.5 1 1 0 2 2 2 0 Cytochrome b562 Spc7 PF08317.11 OAG38454.1 - 0.26 10.2 3.3 0.44 9.4 3.3 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein TRAM1 PF08390.11 OAG38455.1 - 0.0079 15.8 2.1 0.015 15.0 2.1 1.4 1 0 0 1 1 1 1 TRAM1-like protein HET PF06985.11 OAG38456.1 - 3e-07 30.9 0.0 1.5e-05 25.4 0.0 2.6 1 1 1 2 2 2 1 Heterokaryon incompatibility protein (HET) Toxin_12 PF07740.12 OAG38456.1 - 0.015 16.0 3.2 0.041 14.6 3.2 1.8 1 0 0 1 1 1 0 Ion channel inhibitory toxin GTP_CH_N PF12471.8 OAG38457.1 - 7.8e-89 296.5 0.0 1.1e-88 296.1 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.20 OAG38457.1 - 2.4e-18 66.3 0.0 3.7e-18 65.7 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase II GntR PF00392.21 OAG38457.1 - 0.05 13.3 0.1 1.9 8.2 0.0 2.7 3 0 0 3 3 3 0 Bacterial regulatory proteins, gntR family DUF1688 PF07958.11 OAG38458.1 - 4e-148 493.6 0.0 4.4e-148 493.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) Q_salvage PF10343.9 OAG38458.1 - 0.011 15.3 0.0 3.5 7.1 0.0 2.3 2 0 0 2 2 2 0 Potential Queuosine, Q, salvage protein family UPRTase PF14681.6 OAG38459.1 - 5.9e-55 185.9 0.2 1.7e-50 171.4 0.0 2.0 1 1 1 2 2 2 2 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 OAG38459.1 - 3.2e-06 26.7 0.0 5e-06 26.1 0.0 1.3 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Aldedh PF00171.22 OAG38460.1 - 2.2e-129 432.0 0.3 2.8e-129 431.7 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 OAG38460.1 - 6e-05 22.3 0.0 0.00011 21.4 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) OmdA PF13376.6 OAG38460.1 - 0.038 14.0 0.1 0.081 12.9 0.1 1.6 1 0 0 1 1 1 0 Bacteriocin-protection, YdeI or OmpD-Associated Pribosyltran_N PF13793.6 OAG38461.1 - 3.1e-41 140.0 0.0 3.5e-40 136.6 0.0 2.2 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 OAG38461.1 - 4.1e-31 108.4 5.2 4.3e-29 101.8 0.9 2.7 2 1 1 3 3 3 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 OAG38461.1 - 2.6e-09 36.8 1.0 4.9e-09 35.9 1.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 OAG38461.1 - 0.012 15.1 0.4 0.021 14.2 0.4 1.4 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Pam17 PF08566.10 OAG38461.1 - 0.15 11.9 0.0 0.43 10.4 0.0 1.7 1 0 0 1 1 1 0 Mitochondrial import protein Pam17 UPRTase PF14681.6 OAG38462.1 - 1.3e-59 201.2 0.0 1.6e-59 200.8 0.0 1.1 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 OAG38462.1 - 0.00049 19.7 0.1 0.00062 19.3 0.1 1.4 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Transp_cyt_pur PF02133.15 OAG38463.1 - 1.2e-125 419.8 38.3 1.4e-125 419.5 38.3 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin MOSC PF03473.17 OAG38464.1 - 2.7e-24 85.6 0.0 6.2e-24 84.5 0.0 1.6 1 0 0 1 1 1 1 MOSC domain Fer2 PF00111.27 OAG38464.1 - 3.2e-14 52.6 0.5 6.9e-14 51.6 0.5 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain 3-alpha PF03475.14 OAG38464.1 - 9.4e-08 31.8 0.0 2e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 3-alpha domain NAD_binding_1 PF00175.21 OAG38464.1 - 0.00014 22.4 0.1 0.008 16.8 0.0 2.8 2 1 0 2 2 2 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 OAG38464.1 - 0.00016 21.8 0.1 0.21 11.7 0.0 2.4 1 1 1 2 2 2 2 Ferric reductase NAD binding domain Fer2_4 PF13510.6 OAG38464.1 - 0.015 15.3 0.1 0.039 14.0 0.1 1.7 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain DIOX_N PF14226.6 OAG38465.1 - 1.9e-36 125.4 0.0 3e-36 124.7 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OAG38465.1 - 8.6e-23 80.7 0.0 3e-22 79.0 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily FAD_oxidored PF12831.7 OAG38465.1 - 1.3e-15 57.7 0.1 2e-15 57.1 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase HNH_2 PF13391.6 OAG38467.1 - 4.5e-15 55.5 0.1 2.6e-14 53.1 0.0 2.0 2 0 0 2 2 2 1 HNH endonuclease Dynein_light PF01221.18 OAG38468.1 - 1.5e-40 137.4 1.5 1.7e-40 137.2 1.5 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 RhoGEF67_u1 PF16615.5 OAG38468.1 - 0.058 13.9 0.0 0.088 13.3 0.0 1.2 1 0 0 1 1 1 0 Unstructured region one on RhoGEF 6 and 7 MFS_1 PF07690.16 OAG38469.1 - 3.1e-46 157.9 37.6 3.1e-46 157.9 37.6 1.8 3 0 0 3 3 3 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG38469.1 - 3.8e-09 35.9 27.5 1.7e-08 33.8 26.6 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 OAG38469.1 - 0.0017 16.9 5.0 0.0027 16.2 5.0 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 OAG38469.1 - 0.29 10.4 16.7 0.044 13.1 8.4 2.4 2 0 0 2 2 2 0 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 OAG38469.1 - 0.6 8.3 4.9 0.24 9.6 0.5 2.2 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Ank_2 PF12796.7 OAG38470.1 - 2.2e-60 201.2 0.4 1.6e-12 47.9 0.0 5.2 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OAG38470.1 - 4.2e-27 93.8 2.0 1.1e-07 32.0 0.1 6.9 2 1 6 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG38470.1 - 3.8e-24 82.1 0.1 0.041 14.4 0.0 8.3 8 0 0 8 8 8 6 Ankyrin repeat Ank_4 PF13637.6 OAG38470.1 - 6e-23 80.9 0.2 1.3e-07 32.0 0.0 6.2 4 1 2 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 OAG38470.1 - 4.4e-21 74.3 1.0 0.025 15.0 0.0 8.0 7 1 0 7 7 7 5 Ankyrin repeat AAA_22 PF13401.6 OAG38470.1 - 1.4e-07 31.8 0.0 5.3e-07 30.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 OAG38470.1 - 0.00012 22.0 0.0 0.00031 20.7 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 OAG38470.1 - 0.017 15.5 0.0 0.1 13.0 0.0 2.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.6 OAG38470.1 - 0.077 13.3 0.0 0.27 11.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain GST_N_2 PF13409.6 OAG38471.1 - 5.8e-07 29.7 0.0 1.1e-06 28.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 OAG38471.1 - 4.4e-06 27.0 0.0 1.1e-05 25.7 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 OAG38471.1 - 0.021 15.0 0.0 0.042 14.1 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OAG38471.1 - 0.073 13.1 0.2 0.17 11.9 0.2 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OAG38471.1 - 0.15 12.3 0.0 0.33 11.2 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Helo_like_N PF17111.5 OAG38472.1 - 0.00057 19.3 0.1 0.0012 18.3 0.1 1.6 1 1 0 1 1 1 1 Fungal N-terminal domain of STAND proteins adh_short_C2 PF13561.6 OAG38474.1 - 2.5e-48 164.7 0.0 2.8e-48 164.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG38474.1 - 1.3e-44 152.0 0.1 1.6e-44 151.7 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG38474.1 - 7.5e-10 39.0 0.1 1.1e-09 38.4 0.1 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OAG38474.1 - 0.00024 20.4 0.0 0.00033 19.9 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 OAG38474.1 - 0.0014 18.1 0.1 0.0025 17.3 0.1 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 OAG38474.1 - 0.0068 15.9 0.0 0.015 14.7 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 OAG38474.1 - 0.02 14.8 0.0 0.031 14.2 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding Fungal_trans PF04082.18 OAG38475.1 - 1.8e-07 30.5 0.1 1.2e-06 27.7 0.1 2.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG38475.1 - 9.2e-06 25.7 9.4 1.6e-05 24.9 9.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_30 PF02055.16 OAG38476.1 - 3.2e-20 72.4 0.1 4.2e-20 72.0 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_30C PF17189.4 OAG38476.1 - 0.00045 20.4 2.3 0.00057 20.1 0.0 2.3 2 0 0 2 2 2 1 Glycosyl hydrolase family 30 beta sandwich domain YEATS PF03366.16 OAG38478.1 - 2e-12 46.9 0.5 3.8e-12 46.0 0.5 1.5 1 0 0 1 1 1 1 YEATS family Cyt-b5 PF00173.28 OAG38479.1 - 3.9e-18 65.4 1.0 7e-17 61.3 0.0 2.5 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.13 OAG38479.1 - 2e-10 41.1 24.4 3.5e-10 40.3 23.8 1.7 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Anth_synt_I_N PF04715.13 OAG38479.1 - 0.039 14.1 0.2 0.071 13.3 0.2 1.4 1 0 0 1 1 1 0 Anthranilate synthase component I, N terminal region Glyco_hydro_61 PF03443.14 OAG38480.1 - 0.0032 17.5 0.2 3 7.7 0.0 3.4 2 1 1 3 3 3 2 Glycosyl hydrolase family 61 NmrA PF05368.13 OAG38481.1 - 1.1e-37 129.8 0.0 1.4e-37 129.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG38481.1 - 4.6e-18 65.7 0.0 6e-18 65.4 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAG38481.1 - 1.7e-08 34.2 0.0 6.6e-08 32.3 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OAG38481.1 - 0.0093 15.0 0.0 0.014 14.5 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 OAG38481.1 - 0.026 13.9 0.0 0.042 13.2 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 OAG38481.1 - 0.045 12.9 0.0 1.2 8.3 0.0 2.2 2 0 0 2 2 2 0 Male sterility protein DapB_N PF01113.20 OAG38481.1 - 0.054 13.6 0.0 0.17 12.0 0.0 1.8 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus TMEM171 PF15471.6 OAG38481.1 - 0.068 12.2 0.0 0.12 11.3 0.0 1.4 1 0 0 1 1 1 0 Transmembrane protein family 171 Polysacc_synt_2 PF02719.15 OAG38481.1 - 0.11 11.6 0.0 9.5 5.3 0.0 2.2 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein ADH_N PF08240.12 OAG38482.1 - 1.6e-24 85.9 0.2 3.1e-24 84.9 0.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 OAG38482.1 - 1.6e-14 53.9 0.4 4.8e-08 32.7 0.2 2.4 1 1 1 2 2 2 2 Glucose dehydrogenase C-terminus ADH_zinc_N PF00107.26 OAG38482.1 - 4.2e-14 52.6 0.2 7.2e-14 51.9 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ThiF PF00899.21 OAG38482.1 - 0.0011 18.4 2.1 0.0019 17.6 2.1 1.3 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 OAG38482.1 - 0.03 14.4 0.2 0.057 13.5 0.2 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DAO PF01266.24 OAG38482.1 - 0.04 13.5 0.3 0.058 13.0 0.3 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 OAG38482.1 - 0.076 12.3 1.5 0.12 11.6 1.5 1.2 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 OAG38482.1 - 0.12 11.1 0.6 0.17 10.6 0.6 1.2 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_8 PF13450.6 OAG38482.1 - 0.17 12.1 1.1 0.39 11.0 1.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain 2-Hacid_dh_C PF02826.19 OAG38483.1 - 4.5e-55 185.8 0.0 6.7e-55 185.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 OAG38483.1 - 3.8e-17 62.2 0.0 4.6e-17 61.9 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 OAG38483.1 - 0.00028 21.1 0.1 0.00063 20.0 0.1 1.6 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 OAG38483.1 - 0.14 12.2 0.1 0.64 10.1 0.1 2.1 2 1 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ABC_membrane_2 PF06472.15 OAG38484.1 - 2e-90 302.9 0.5 2.8e-90 302.4 0.5 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 OAG38484.1 - 9.6e-15 55.3 0.0 1.8e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 ABC transporter PLU-1 PF08429.11 OAG38484.1 - 0.023 13.9 0.0 5.3 6.1 0.1 2.2 2 0 0 2 2 2 0 PLU-1-like protein AAA_29 PF13555.6 OAG38484.1 - 0.1 12.3 0.2 0.77 9.6 0.2 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain Helo_like_N PF17111.5 OAG38485.1 - 0.028 13.8 4.2 0.032 13.6 3.5 1.4 1 1 0 1 1 1 0 Fungal N-terminal domain of STAND proteins PBECR5 PF18814.1 OAG38485.1 - 0.057 13.3 9.9 0.084 12.8 9.9 1.1 1 0 0 1 1 1 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease5 DUF1798 PF08807.10 OAG38485.1 - 0.69 10.1 10.9 2.9 8.1 2.5 2.3 1 1 1 2 2 2 0 Bacterial domain of unknown function (DUF1798) BshC PF10079.9 OAG38485.1 - 1.1 8.0 10.3 1.5 7.5 10.3 1.1 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC adh_short PF00106.25 OAG38486.1 - 1.2e-14 54.2 0.0 3.7e-14 52.6 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 OAG38486.1 - 1.4e-09 38.1 0.0 3.6e-09 36.8 0.0 1.6 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.6 OAG38486.1 - 2.2e-08 34.0 0.0 4e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 OAG38486.1 - 0.011 15.2 0.0 0.018 14.5 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family AMP-binding PF00501.28 OAG38487.1 - 4.9e-60 203.3 0.0 7.3e-60 202.7 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG38487.1 - 0.0044 18.0 0.0 0.012 16.6 0.0 1.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain HAMP_N3 PF18575.1 OAG38487.1 - 0.22 11.1 0.2 0.43 10.2 0.2 1.4 1 0 0 1 1 1 0 HAMP N-terminal domain 3 Fungal_trans PF04082.18 OAG38488.1 - 0.012 14.6 0.0 0.021 13.9 0.0 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain MFS_1 PF07690.16 OAG38489.1 - 1.6e-31 109.5 30.1 2.4e-31 108.9 30.1 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Ac110_PIF PF07280.11 OAG38489.1 - 0.014 15.2 0.2 0.044 13.6 0.2 1.9 1 0 0 1 1 1 0 Per os infectivity factor AC110 Glyco_hydro_31 PF01055.26 OAG38490.1 - 9e-90 301.9 1.4 1.1e-89 301.6 1.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 OAG38490.1 - 1.1e-10 41.6 0.1 5.8e-10 39.4 0.0 2.3 2 0 0 2 2 2 1 Galactose mutarotase-like MFS_1 PF07690.16 OAG38491.1 - 4.1e-17 62.1 52.6 1.6e-16 60.2 48.9 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 OAG38491.1 - 8.4e-10 37.7 11.4 8.4e-10 37.7 11.4 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) SNF2_N PF00176.23 OAG38492.1 - 7.4e-62 209.1 0.1 7.4e-62 209.1 0.1 2.0 2 1 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OAG38492.1 - 1.9e-16 60.4 0.0 4e-16 59.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.6 OAG38492.1 - 1.9e-07 30.8 2.7 3.5e-07 30.0 2.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAG38492.1 - 3.3e-07 30.1 4.7 6.3e-07 29.2 4.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAG38492.1 - 8.1e-07 29.0 4.3 1.8e-06 27.9 4.3 1.6 1 0 0 1 1 1 1 RING-type zinc-finger ResIII PF04851.15 OAG38492.1 - 1.1e-06 28.8 0.0 5.3e-06 26.6 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-C3HC4_2 PF13923.6 OAG38492.1 - 2.4e-06 27.2 5.1 6.2e-06 26.0 5.1 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAG38492.1 - 7.2e-06 26.2 4.8 1.5e-05 25.2 4.8 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 OAG38492.1 - 1.8e-05 24.6 4.6 3.4e-05 23.7 4.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 OAG38492.1 - 3.4e-05 23.9 7.5 6.1e-05 23.1 7.5 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 OAG38492.1 - 0.0006 19.6 5.7 0.0015 18.4 5.7 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 AAA_34 PF13872.6 OAG38492.1 - 0.0021 17.0 0.1 0.0064 15.4 0.0 1.7 2 0 0 2 2 2 1 P-loop containing NTP hydrolase pore-1 PhoH PF02562.16 OAG38492.1 - 0.023 14.2 0.0 0.046 13.2 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Baculo_IE-1 PF05290.11 OAG38492.1 - 0.025 14.5 0.4 0.05 13.5 0.4 1.4 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-RING_4 PF14570.6 OAG38492.1 - 0.037 13.8 4.7 0.09 12.6 4.7 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain ERCC3_RAD25_C PF16203.5 OAG38492.1 - 0.042 13.1 0.0 0.091 12.0 0.0 1.5 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase NOA36 PF06524.12 OAG38492.1 - 0.059 12.7 16.0 0.12 11.7 16.0 1.4 1 0 0 1 1 1 0 NOA36 protein FYVE PF01363.21 OAG38492.1 - 0.075 13.2 2.0 0.17 12.0 2.0 1.6 1 0 0 1 1 1 0 FYVE zinc finger Gin PF10764.9 OAG38492.1 - 0.2 11.6 1.2 0.49 10.4 1.2 1.7 1 0 0 1 1 1 0 Inhibitor of sigma-G Gin DNA_pol_phi PF04931.13 OAG38492.1 - 2.7 6.0 11.4 5.4 5.0 11.4 1.6 1 0 0 1 1 1 0 DNA polymerase phi YL1 PF05764.13 OAG38492.1 - 4.3 7.4 33.3 1.1 9.3 17.9 2.5 2 0 0 2 2 2 0 YL1 nuclear protein adh_short PF00106.25 OAG38493.1 - 3.1e-25 88.8 0.0 3.9e-25 88.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG38493.1 - 7.2e-17 61.7 0.0 9.4e-17 61.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG38493.1 - 0.00012 22.0 0.0 0.031 14.2 0.0 2.2 2 0 0 2 2 2 2 KR domain DUF1776 PF08643.10 OAG38493.1 - 0.0016 17.8 0.0 0.0032 16.9 0.0 1.4 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) 3HCDH_N PF02737.18 OAG38493.1 - 0.083 12.8 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain LysM PF01476.20 OAG38494.1 - 0.00011 22.1 0.0 0.00022 21.2 0.0 1.5 1 0 0 1 1 1 1 LysM domain UBA_4 PF14555.6 OAG38494.1 - 0.0051 16.6 0.1 0.0085 15.9 0.1 1.3 1 0 0 1 1 1 1 UBA-like domain DUF2156 PF09924.9 OAG38495.1 - 4e-30 104.8 0.0 5.8e-30 104.3 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2156) ubiquitin PF00240.23 OAG38496.1 - 7.1e-08 32.1 0.0 1.6e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 OAG38496.1 - 0.00016 22.2 0.0 0.00048 20.7 0.0 1.7 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain TFIIA PF03153.13 OAG38496.1 - 1.6 8.6 17.3 0.004 17.2 3.3 2.4 1 1 1 2 2 2 0 Transcription factor IIA, alpha/beta subunit PS_Dcarbxylase PF02666.15 OAG38497.1 - 1.4e-79 266.3 0.0 6.4e-78 260.9 0.0 2.2 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase FMN_dh PF01070.18 OAG38499.1 - 1.8e-117 392.3 0.0 2.1e-117 392.1 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 OAG38499.1 - 1.3e-06 27.7 0.5 2.2e-05 23.6 0.2 2.4 2 1 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 OAG38499.1 - 3.7e-05 23.0 0.3 0.00013 21.2 0.1 1.8 1 1 1 2 2 2 1 Conserved region in glutamate synthase His_biosynth PF00977.21 OAG38499.1 - 0.0023 17.5 0.4 0.33 10.4 0.0 3.1 3 1 1 4 4 4 2 Histidine biosynthesis protein ThiG PF05690.14 OAG38499.1 - 0.017 14.4 0.0 8.8 5.6 0.0 3.1 2 1 1 3 3 3 0 Thiazole biosynthesis protein ThiG DUF3433 PF11915.8 OAG38501.1 - 4.3e-33 113.6 15.1 1.5e-26 92.6 2.2 3.3 4 0 0 4 4 4 2 Protein of unknown function (DUF3433) CadC_C1 PF18500.1 OAG38501.1 - 0.084 13.0 0.8 2.2 8.4 0.0 2.6 2 0 0 2 2 2 0 CadC C-terminal domain 1 DUF682 PF05081.12 OAG38503.1 - 0.16 11.7 0.0 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF682) DUF3425 PF11905.8 OAG38505.1 - 5.3e-15 55.5 0.1 1.7e-14 53.9 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Fungal_trans_2 PF11951.8 OAG38505.1 - 0.0012 17.7 2.0 0.0024 16.7 0.1 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain Peptidase_C97 PF05903.14 OAG38505.1 - 0.14 11.9 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 PPPDE putative peptidase domain Sugar_tr PF00083.24 OAG38506.1 - 2.7e-83 280.4 21.8 3.1e-83 280.1 21.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG38506.1 - 4.2e-28 98.3 40.4 7.2e-22 77.8 20.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 OAG38509.1 - 9e-19 67.6 32.6 1.3e-18 67.1 32.6 1.2 1 1 0 1 1 1 1 Major Facilitator Superfamily Sec62 PF03839.16 OAG38509.1 - 0.045 13.2 1.2 0.14 11.7 1.2 1.8 1 0 0 1 1 1 0 Translocation protein Sec62 Tri3 PF07428.11 OAG38510.1 - 4e-06 26.0 0.0 0.0068 15.4 0.0 2.2 2 0 0 2 2 2 2 15-O-acetyltransferase Tri3 DUF4681 PF15732.5 OAG38510.1 - 0.0043 17.3 0.0 0.0076 16.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4681) Oxidored_FMN PF00724.20 OAG38511.1 - 7.2e-79 265.5 0.0 8.3e-79 265.3 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family FMO-like PF00743.19 OAG38512.1 - 3.9e-29 101.5 0.0 2.8e-14 52.5 0.0 3.1 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OAG38512.1 - 6e-13 48.7 0.0 6.2e-08 32.3 0.0 3.2 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAG38512.1 - 1.2e-06 28.0 0.0 1.4e-05 24.4 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAG38512.1 - 2.2e-05 24.5 0.1 0.00091 19.3 0.0 2.7 2 0 0 2 2 2 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 OAG38512.1 - 4e-05 22.9 0.2 0.051 12.7 0.0 3.4 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 OAG38512.1 - 0.005 17.0 0.0 0.013 15.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 OAG38512.1 - 0.026 13.8 0.1 0.096 11.9 0.0 1.8 2 0 0 2 2 2 0 Thi4 family DAO PF01266.24 OAG38512.1 - 0.027 14.0 0.1 2.6 7.5 0.1 2.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase p450 PF00067.22 OAG38513.1 - 3.3e-63 214.0 0.0 4.3e-63 213.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 OAG38514.1 - 7.6e-33 113.9 26.6 7.6e-33 113.9 26.6 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Cg6151-P PF10233.9 OAG38514.1 - 0.14 12.5 4.0 0.4 11.0 4.0 1.8 1 0 0 1 1 1 0 Uncharacterized conserved protein CG6151-P ATP19 PF11022.8 OAG38514.1 - 0.18 12.2 0.0 0.58 10.6 0.0 1.8 1 0 0 1 1 1 0 ATP synthase subunit K Fungal_trans PF04082.18 OAG38515.1 - 1.1e-29 103.3 6.8 1.7e-29 102.7 6.8 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain bZIP_Maf PF03131.17 OAG38516.1 - 0.015 15.8 3.9 0.028 14.9 3.9 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor bZIP_1 PF00170.21 OAG38516.1 - 1 9.5 7.2 1.8 8.7 7.2 1.3 1 0 0 1 1 1 0 bZIP transcription factor adh_short PF00106.25 OAG38517.1 - 5.5e-40 136.9 0.5 7.7e-40 136.4 0.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG38517.1 - 4.6e-24 85.3 0.4 7.8e-24 84.5 0.4 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 OAG38517.1 - 9.1e-07 28.9 0.0 1.5e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 OAG38517.1 - 0.00021 20.9 0.1 0.00033 20.3 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family PALP PF00291.25 OAG38517.1 - 0.00037 20.0 0.8 0.0077 15.7 0.3 2.1 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme ADH_zinc_N PF00107.26 OAG38517.1 - 0.00076 19.5 0.2 0.0013 18.7 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ApbA PF02558.16 OAG38517.1 - 0.001 18.7 0.1 0.0016 18.1 0.1 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA DUF1776 PF08643.10 OAG38517.1 - 0.0012 18.3 0.0 0.058 12.8 0.0 2.1 1 1 1 2 2 2 1 Fungal family of unknown function (DUF1776) FAD_binding_3 PF01494.19 OAG38517.1 - 0.0016 17.8 0.0 0.0022 17.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Epimerase PF01370.21 OAG38517.1 - 0.0028 17.2 0.6 0.0064 16.0 0.6 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_2 PF03446.15 OAG38517.1 - 0.01 16.0 0.1 0.027 14.7 0.0 1.6 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase DFP PF04127.15 OAG38517.1 - 0.019 14.8 0.5 0.035 13.9 0.5 1.4 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein RmlD_sub_bind PF04321.17 OAG38517.1 - 0.023 13.8 0.1 0.039 13.0 0.1 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain 2-Hacid_dh_C PF02826.19 OAG38517.1 - 0.03 13.7 0.0 0.059 12.7 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 OAG38517.1 - 0.046 14.0 0.0 0.076 13.3 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain adh_short_C2 PF13561.6 OAG38518.1 - 2.4e-36 125.5 2.8 8.1e-36 123.7 2.8 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG38518.1 - 6.1e-31 107.4 1.0 1.2e-30 106.5 1.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG38518.1 - 0.0002 21.3 0.3 0.0002 21.3 0.3 1.4 2 0 0 2 2 2 1 KR domain Thiolase_N PF00108.23 OAG38519.1 - 7.1e-10 38.7 0.0 2.4e-07 30.4 0.0 2.5 3 0 0 3 3 3 2 Thiolase, N-terminal domain Thiolase_C PF02803.18 OAG38519.1 - 1.4e-09 37.7 0.1 4.5e-09 36.0 0.1 1.9 1 1 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III PF08545.10 OAG38519.1 - 7.3e-06 25.7 0.0 0.00098 18.9 0.0 2.6 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Ketoacyl-synt_C PF02801.22 OAG38519.1 - 0.0044 17.0 0.1 0.063 13.3 0.0 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain ketoacyl-synt PF00109.26 OAG38519.1 - 0.012 15.2 0.4 0.15 11.6 0.0 2.5 2 1 0 3 3 3 0 Beta-ketoacyl synthase, N-terminal domain DUF3433 PF11915.8 OAG38520.1 - 3e-18 66.1 4.2 8.4e-13 48.6 0.8 3.1 2 1 0 2 2 2 2 Protein of unknown function (DUF3433) DIOX_N PF14226.6 OAG38521.1 - 3e-28 99.0 0.0 4.1e-28 98.5 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OAG38521.1 - 4.6e-25 88.0 0.0 1.1e-24 86.8 0.0 1.6 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily APH PF01636.23 OAG38522.1 - 0.062 13.2 1.0 0.18 11.7 1.0 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family Methyltransf_23 PF13489.6 OAG38523.1 - 6.9e-16 58.5 0.0 1.5e-15 57.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG38523.1 - 3e-07 31.0 0.0 6.5e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG38523.1 - 2.3e-05 24.3 0.0 0.00011 22.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG38523.1 - 0.0056 17.3 0.0 0.013 16.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG38523.1 - 0.019 15.7 0.0 0.048 14.4 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 OAG38523.1 - 0.024 14.2 0.0 0.091 12.3 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase small domain FtsJ PF01728.19 OAG38523.1 - 0.034 14.3 0.0 0.05 13.7 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase PrmA PF06325.13 OAG38523.1 - 0.17 11.3 0.3 0.44 9.9 0.1 1.7 1 1 1 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Actin PF00022.19 OAG38524.1 - 6.7e-130 433.4 0.0 7.5e-130 433.2 0.0 1.0 1 0 0 1 1 1 1 Actin 5HT_transport_N PF03491.13 OAG38524.1 - 0.18 12.0 0.0 0.44 10.8 0.0 1.6 1 0 0 1 1 1 0 Serotonin (5-HT) neurotransmitter transporter, N-terminus Peripla_BP_5 PF13433.6 OAG38526.1 - 0.0048 15.9 0.4 0.007 15.4 0.2 1.3 1 1 1 2 2 2 1 Periplasmic binding protein domain Tudor_RapA PF18337.1 OAG38526.1 - 0.14 12.3 0.0 0.27 11.4 0.0 1.4 1 0 0 1 1 1 0 RapA N-terminal Tudor like domain rRNA_processing PF08524.11 OAG38526.1 - 0.23 11.5 21.7 1.1 9.3 21.6 1.8 1 1 0 1 1 1 0 rRNA processing DUF4210 PF13915.6 OAG38527.1 - 2.6e-32 111.2 0.2 5.4e-32 110.2 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.6 OAG38527.1 - 9e-24 83.4 0.5 2.5e-23 82.0 0.5 1.8 1 0 0 1 1 1 1 Chromosome segregation during meiosis KH_1 PF00013.29 OAG38528.1 - 9.9e-33 111.8 4.6 2.6e-07 30.3 0.0 7.4 7 0 0 7 7 7 7 KH domain SUV3_C PF12513.8 OAG38528.1 - 0.048 13.6 0.0 0.13 12.2 0.0 1.8 1 0 0 1 1 1 0 Mitochondrial degradasome RNA helicase subunit C terminal Dynactin PF12455.8 OAG38529.1 - 9.1e-73 245.0 8.7 9.1e-73 245.0 8.7 4.5 4 2 0 4 4 4 1 Dynein associated protein CAP_GLY PF01302.25 OAG38529.1 - 1.3e-23 82.8 0.7 2.4e-23 81.9 0.7 1.4 1 0 0 1 1 1 1 CAP-Gly domain MAD PF05557.13 OAG38529.1 - 0.00063 18.2 87.8 0.0063 15.0 57.3 2.6 3 0 0 3 3 3 2 Mitotic checkpoint protein TSC22 PF01166.18 OAG38529.1 - 0.2 12.0 0.1 0.2 12.0 0.1 9.3 8 2 1 9 9 9 0 TSC-22/dip/bun family Na_Ca_ex PF01699.24 OAG38530.1 - 2.5e-45 154.1 36.2 1.2e-23 83.7 15.6 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Ribosomal_S7 PF00177.21 OAG38531.1 - 3.5e-30 104.6 0.1 8.2e-30 103.4 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein S7p/S5e DUF2285 PF10074.9 OAG38531.1 - 0.026 15.2 2.4 0.09 13.4 2.4 1.9 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2285) Amastin PF07344.11 OAG38532.1 - 8.8 6.1 13.8 0.21 11.4 1.9 2.6 2 1 0 2 2 2 0 Amastin surface glycoprotein DUF3237 PF11578.8 OAG38533.1 - 1.6e-17 63.8 0.0 2.4e-17 63.1 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3237) adh_short_C2 PF13561.6 OAG38534.1 - 3.2e-67 226.5 1.4 3.7e-67 226.3 1.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG38534.1 - 2e-47 161.2 2.3 2.6e-47 160.8 2.3 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG38534.1 - 1.2e-12 48.1 2.9 1.6e-12 47.7 2.9 1.1 1 0 0 1 1 1 1 KR domain AhpC-TSA PF00578.21 OAG38534.1 - 0.17 11.8 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 AhpC/TSA family FMO-like PF00743.19 OAG38535.1 - 1.6e-15 56.6 0.0 5.9e-12 44.8 0.0 2.2 1 1 1 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OAG38535.1 - 3.1e-07 30.5 0.0 9.3e-07 29.0 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 OAG38535.1 - 5.3e-06 25.8 0.0 0.0086 15.3 0.0 3.0 3 1 0 4 4 4 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 OAG38535.1 - 8e-06 25.3 0.0 0.0068 15.7 0.0 3.3 2 1 2 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAG38535.1 - 4.6e-05 23.2 0.0 0.00022 20.9 0.0 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG38535.1 - 7.6e-05 22.1 0.0 0.00049 19.4 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAG38535.1 - 0.0026 17.0 0.0 0.054 12.7 0.0 2.2 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.22 OAG38535.1 - 0.0042 16.2 0.0 0.82 8.7 0.0 3.0 3 0 0 3 3 3 1 Glucose inhibited division protein A HI0933_like PF03486.14 OAG38535.1 - 0.011 14.4 0.0 0.034 12.9 0.0 1.7 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_9 PF13454.6 OAG38535.1 - 0.012 15.6 0.3 0.044 13.8 0.0 2.2 3 0 0 3 3 3 0 FAD-NAD(P)-binding PRMT5 PF05185.16 OAG38535.1 - 0.5 10.2 3.0 7 6.5 0.1 2.9 2 1 1 3 3 3 0 PRMT5 arginine-N-methyltransferase Sugar_tr PF00083.24 OAG38536.1 - 5.8e-84 282.5 24.2 6.7e-84 282.3 24.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG38536.1 - 1.2e-23 83.7 34.0 6.5e-18 64.8 20.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily RPAP1_N PF08621.10 OAG38536.1 - 0.055 13.2 0.2 0.11 12.3 0.2 1.4 1 0 0 1 1 1 0 RPAP1-like, N-terminal Kinocilin PF15033.6 OAG38536.1 - 0.13 12.0 1.5 0.38 10.4 1.5 1.7 1 0 0 1 1 1 0 Kinocilin protein Phage_holin_3_2 PF04550.12 OAG38536.1 - 1.7 9.2 5.3 3.1 8.4 3.5 2.4 2 1 0 2 2 2 0 Phage holin family 2 adh_short PF00106.25 OAG38537.1 - 4.6e-15 55.6 0.0 6.9e-15 55.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG38537.1 - 4.4e-11 42.8 0.0 6.3e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Fungal_trans PF04082.18 OAG38538.1 - 7.4e-16 58.0 0.1 1.3e-15 57.1 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short_C2 PF13561.6 OAG38539.1 - 7.9e-66 222.0 3.3 8.9e-66 221.8 3.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG38539.1 - 3.3e-48 163.7 1.8 4.2e-48 163.4 1.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG38539.1 - 1.4e-09 38.2 1.6 2.1e-09 37.5 1.6 1.2 1 0 0 1 1 1 1 KR domain Ubie_methyltran PF01209.18 OAG38539.1 - 0.066 12.5 0.1 0.1 11.9 0.1 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family DUF2034 PF10356.9 OAG38540.1 - 1.9e-25 89.4 0.0 3.2e-21 75.6 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2034) Mrr_cat PF04471.12 OAG38540.1 - 4.8e-07 29.8 0.1 6e-06 26.3 0.0 2.5 2 1 0 2 2 2 1 Restriction endonuclease Carn_acyltransf PF00755.20 OAG38541.1 - 1.2e-197 658.2 0.0 1.3e-197 658.0 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase MutL_C PF08676.11 OAG38542.1 - 2.3e-24 85.9 0.1 8.7e-24 84.0 0.0 2.1 2 0 0 2 2 2 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 OAG38542.1 - 1.4e-21 76.4 0.2 1.3e-20 73.2 0.0 2.7 3 0 0 3 3 3 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 OAG38542.1 - 1.5e-10 41.0 0.0 5.1e-10 39.3 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 OAG38542.1 - 4.7e-05 23.8 0.0 0.00013 22.5 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase F-box-like PF12937.7 OAG38543.1 - 0.003 17.4 0.0 0.0088 15.9 0.0 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAG38543.1 - 0.041 13.8 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 F-box domain NAD_binding_2 PF03446.15 OAG38544.1 - 4.9e-30 104.8 0.3 8e-30 104.1 0.3 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 OAG38544.1 - 9e-20 71.1 0.0 1.8e-19 70.2 0.0 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Creatinase_N PF01321.18 OAG38544.1 - 0.16 12.6 0.0 0.28 11.8 0.0 1.4 1 0 0 1 1 1 0 Creatinase/Prolidase N-terminal domain Complex1_LYR_2 PF13233.6 OAG38545.1 - 9.1e-22 77.6 0.8 1.1e-21 77.3 0.8 1.1 1 0 0 1 1 1 1 Complex1_LYR-like DUF3819 PF12842.7 OAG38545.1 - 0.11 12.4 0.0 0.15 12.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3819) Clr5 PF14420.6 OAG38546.1 - 2.4e-07 30.9 0.7 5e-07 29.8 0.7 1.5 1 0 0 1 1 1 1 Clr5 domain TPR_12 PF13424.6 OAG38546.1 - 0.012 15.9 0.2 2.5 8.5 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Clr5 PF14420.6 OAG38547.1 - 2.6e-13 50.0 0.4 6.4e-13 48.7 0.4 1.7 1 0 0 1 1 1 1 Clr5 domain TPR_12 PF13424.6 OAG38547.1 - 1.2 9.5 7.1 3.7 7.9 0.1 3.5 3 1 0 3 3 3 0 Tetratricopeptide repeat Clr5 PF14420.6 OAG38548.1 - 2.7e-15 56.3 0.4 6.2e-15 55.2 0.4 1.7 1 0 0 1 1 1 1 Clr5 domain GPI-anchored PF10342.9 OAG38549.1 - 1.2e-07 32.4 1.0 1.2e-07 32.4 1.0 2.3 1 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family ENTH PF01417.20 OAG38550.1 - 3.8e-48 162.6 0.0 5.9e-48 162.0 0.0 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 OAG38550.1 - 0.00029 19.9 0.0 0.00042 19.4 0.0 1.2 1 0 0 1 1 1 1 ANTH domain DUF1720 PF08226.11 OAG38550.1 - 0.00039 20.8 39.0 0.00039 20.8 39.0 5.6 1 1 2 3 3 3 1 Domain of unknown function (DUF1720) DUF4264 PF14084.6 OAG38550.1 - 0.07 12.8 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4264) ABM PF03992.16 OAG38551.1 - 3.9e-06 26.9 1.4 0.00025 21.1 0.3 2.8 2 1 0 2 2 2 2 Antibiotic biosynthesis monooxygenase Ribonuclease_T2 PF00445.18 OAG38552.1 - 1.1e-36 126.7 0.0 1.8e-36 126.1 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family DUF1751 PF08551.10 OAG38553.1 - 2.9e-25 88.7 1.9 5.3e-25 87.9 1.9 1.4 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.22 OAG38553.1 - 2.8e-05 24.1 5.1 2.8e-05 24.1 5.1 1.5 2 0 0 2 2 2 1 Rhomboid family WD40 PF00400.32 OAG38554.1 - 2.5e-08 34.4 2.6 0.097 13.6 0.0 4.9 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG38554.1 - 1.2e-07 31.9 0.0 5.3e-05 23.4 0.0 3.7 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 OAG38554.1 - 0.00042 20.2 0.7 0.0015 18.5 0.2 2.2 2 0 0 2 2 2 1 LisH Ge1_WD40 PF16529.5 OAG38554.1 - 0.018 14.0 0.0 9.9 5.0 0.0 2.9 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 OAG38554.1 - 0.072 13.0 0.0 0.26 11.2 0.0 2.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A Rootletin PF15035.6 OAG38555.1 - 0.0064 16.5 11.1 0.0064 16.5 11.1 1.6 2 0 0 2 2 2 1 Ciliary rootlet component, centrosome cohesion YabA PF06156.13 OAG38555.1 - 0.01 16.5 4.5 0.01 16.5 4.5 2.1 2 1 0 2 2 2 0 Initiation control protein YabA WD40_alt PF14077.6 OAG38555.1 - 0.025 14.4 0.2 0.071 13.0 0.2 1.7 1 0 0 1 1 1 0 Alternative WD40 repeat motif DUF29 PF01724.16 OAG38555.1 - 0.12 12.6 6.5 0.08 13.2 3.1 2.0 2 0 0 2 2 2 0 Domain of unknown function DUF29 SHE3 PF17078.5 OAG38555.1 - 0.67 9.6 11.4 2.7 7.6 9.5 2.1 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 DUF1664 PF07889.12 OAG38555.1 - 0.95 9.5 10.6 3.1 7.9 3.7 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF2924 PF11149.8 OAG38555.1 - 1.3 9.4 4.3 0.92 9.9 1.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2924) TSNAXIP1_N PF15739.5 OAG38555.1 - 1.4 9.4 11.9 0.1 13.0 5.3 2.4 3 0 0 3 3 3 0 Translin-associated factor X-interacting N-terminus CENP-H PF05837.12 OAG38555.1 - 1.4 9.4 17.6 0.053 13.9 7.4 2.7 1 1 0 2 2 2 0 Centromere protein H (CENP-H) Nup54 PF13874.6 OAG38555.1 - 1.4 9.0 16.0 0.099 12.7 9.5 2.2 3 0 0 3 3 3 0 Nucleoporin complex subunit 54 Ax_dynein_light PF10211.9 OAG38555.1 - 1.6 8.6 12.3 0.088 12.8 5.9 2.0 2 0 0 2 2 2 0 Axonemal dynein light chain ZapB PF06005.12 OAG38555.1 - 2.3 8.7 13.6 0.13 12.7 3.8 3.3 2 1 2 4 4 4 0 Cell division protein ZapB Atg14 PF10186.9 OAG38555.1 - 2.6 7.1 10.9 3.9 6.5 10.9 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DivIC PF04977.15 OAG38555.1 - 3.6 7.4 9.6 0.2 11.4 3.6 2.0 2 1 0 2 2 2 0 Septum formation initiator Spc7 PF08317.11 OAG38555.1 - 4.6 6.0 18.1 0.15 10.9 9.8 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein Herpes_UL6 PF01763.16 OAG38555.1 - 4.9 5.6 7.8 1.6 7.1 4.7 1.6 2 1 1 3 3 3 0 Herpesvirus UL6 like Chorismate_bind PF00425.18 OAG38556.1 - 1.5e-89 300.0 0.0 2.3e-89 299.4 0.0 1.3 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 OAG38556.1 - 5.6e-29 101.2 0.0 2.5e-25 89.3 0.0 3.6 3 1 0 3 3 3 3 Anthranilate synthase component I, N terminal region Ribosomal_S6e PF01092.19 OAG38557.1 - 5.9e-59 197.5 1.0 8.8e-59 196.9 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein S6e Pribosyltran_N PF13793.6 OAG38558.1 - 3.8e-43 146.1 0.2 9.2e-43 144.9 0.1 1.7 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 OAG38558.1 - 2.8e-34 118.8 0.5 2.7e-28 99.3 0.5 2.6 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 OAG38558.1 - 1.1e-15 57.6 0.3 5.4e-15 55.3 0.1 2.0 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 OAG38558.1 - 0.0037 16.7 0.1 0.0074 15.8 0.1 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase DUF1719 PF08224.11 OAG38559.1 - 0.12 11.4 8.3 0.25 10.4 8.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1719) Nop14 PF04147.12 OAG38559.1 - 0.84 7.8 6.5 0.99 7.5 6.5 1.1 1 0 0 1 1 1 0 Nop14-like family Fungal_trans_2 PF11951.8 OAG38560.1 - 5.4e-05 22.2 0.2 0.00011 21.2 0.1 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain RPN7 PF10602.9 OAG38560.1 - 0.083 12.6 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 26S proteasome subunit RPN7 ADH_zinc_N PF00107.26 OAG38561.1 - 9.5e-11 41.8 0.1 2.4e-10 40.5 0.1 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG38561.1 - 1.1e-06 28.5 0.0 1e-05 25.4 0.0 2.3 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 OAG38561.1 - 0.00046 21.2 0.6 0.0092 17.0 0.2 2.7 1 1 1 2 2 2 1 Zinc-binding dehydrogenase adh_short PF00106.25 OAG38561.1 - 0.017 14.6 0.1 0.028 13.9 0.1 1.3 1 0 0 1 1 1 0 short chain dehydrogenase Polysacc_synt_2 PF02719.15 OAG38561.1 - 0.078 12.1 0.0 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein zinc_ribbon_5 PF13719.6 OAG38562.1 - 0.047 13.4 0.2 0.094 12.5 0.2 1.4 1 0 0 1 1 1 0 zinc-ribbon domain PHP PF02811.19 OAG38562.1 - 0.083 13.2 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 PHP domain WW_like PF17890.1 OAG38564.1 - 0.013 15.5 0.4 0.044 13.9 0.4 1.9 1 0 0 1 1 1 0 Peptidoglycan hydrolase LytB WW-like domain ADH_zinc_N PF00107.26 OAG38565.1 - 4.4e-22 78.5 0.6 4.4e-22 78.5 0.6 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAG38565.1 - 4.7e-12 47.1 0.1 1.4e-11 45.5 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG38565.1 - 1.5e-08 34.4 0.0 4.7e-08 32.9 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 OAG38565.1 - 0.00073 19.1 0.1 0.00099 18.6 0.1 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus NIL PF09383.10 OAG38565.1 - 0.046 13.6 0.0 0.15 11.9 0.0 1.9 2 0 0 2 2 2 0 NIL domain adh_short PF00106.25 OAG38565.1 - 0.17 11.3 1.8 0.64 9.4 1.6 2.1 1 1 0 1 1 1 0 short chain dehydrogenase Aminotran_5 PF00266.19 OAG38566.1 - 1.2e-22 80.4 0.0 3.5e-22 78.9 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 OAG38566.1 - 1.2e-05 24.7 0.0 4.3e-05 22.8 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class I and II SepSecS PF05889.13 OAG38566.1 - 0.0097 14.6 0.0 0.015 14.0 0.0 1.2 1 0 0 1 1 1 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Cys_Met_Meta_PP PF01053.20 OAG38566.1 - 0.033 12.7 0.0 0.11 11.0 0.0 1.7 1 1 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 OAG38566.1 - 0.04 13.2 0.0 8.9 5.5 0.0 2.1 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Rieske PF00355.26 OAG38566.1 - 0.11 12.4 0.1 3 7.8 0.1 2.3 2 0 0 2 2 2 0 Rieske [2Fe-2S] domain F-box-like PF12937.7 OAG38567.1 - 3.8e-07 29.9 0.1 1.5e-06 28.0 0.1 2.1 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.6 OAG38567.1 - 9e-06 25.4 3.2 3 8.1 0.2 5.8 5 0 0 5 5 5 2 Leucine Rich repeat F-box PF00646.33 OAG38567.1 - 0.0018 18.1 0.1 0.048 13.5 0.2 3.3 2 1 0 2 2 2 1 F-box domain HET PF06985.11 OAG38568.1 - 3.3e-24 85.9 0.0 6.3e-24 85.0 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Fungal_trans PF04082.18 OAG38569.1 - 1.3e-18 67.0 0.1 2.1e-18 66.3 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG38569.1 - 3.3e-08 33.5 12.2 5.9e-08 32.7 12.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Opy2 PF09463.10 OAG38569.1 - 3.5 8.0 9.0 0.4 11.0 4.1 1.9 2 0 0 2 2 2 0 Opy2 protein DHquinase_I PF01487.15 OAG38570.1 - 3.2e-21 76.6 0.0 6e-21 75.8 0.0 1.4 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.22 OAG38570.1 - 9e-17 61.6 0.1 2.4e-16 60.2 0.0 1.7 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.11 OAG38570.1 - 4.8e-14 52.4 0.0 1.1e-13 51.2 0.0 1.7 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 OAG38570.1 - 1.1e-08 34.6 0.2 2.4e-08 33.6 0.2 1.6 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 OAG38570.1 - 6.7e-08 32.7 0.0 1.3e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 OAG38570.1 - 0.14 12.6 0.0 0.3 11.6 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Complex1_51K PF01512.17 OAG38571.1 - 3.9e-45 153.4 0.0 6e-45 152.8 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 OAG38571.1 - 1e-28 99.2 0.3 2.2e-28 98.2 0.3 1.6 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 OAG38571.1 - 1.5e-09 37.5 0.0 3.7e-09 36.3 0.0 1.7 1 0 0 1 1 1 1 SLBB domain DUF3568 PF12092.8 OAG38571.1 - 0.17 12.0 0.2 0.34 11.0 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3568) SET PF00856.28 OAG38572.1 - 0.012 16.0 0.0 0.021 15.2 0.0 1.5 1 0 0 1 1 1 0 SET domain Peptidase_M20 PF01546.28 OAG38573.1 - 1.6e-30 106.3 0.1 2.4e-30 105.8 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 OAG38573.1 - 0.00016 21.5 0.1 0.00041 20.2 0.1 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 OAG38573.1 - 0.00051 19.8 0.0 0.00097 18.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 ANAPC15 PF15243.6 OAG38573.1 - 0.038 14.4 0.0 0.069 13.6 0.0 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 Glyco_transf_34 PF05637.12 OAG38574.1 - 3.2e-54 184.2 0.1 4.6e-54 183.7 0.1 1.2 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family 3-PAP PF12578.8 OAG38574.1 - 0.099 12.4 0.1 0.48 10.2 0.0 2.0 2 0 0 2 2 2 0 Myotubularin-associated protein Steroid_dh PF02544.16 OAG38576.1 - 9.4e-32 110.1 0.3 1.3e-31 109.6 0.3 1.2 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.13 OAG38576.1 - 0.00013 22.3 0.1 0.00028 21.2 0.1 1.6 1 0 0 1 1 1 1 Phospholipid methyltransferase DUF1295 PF06966.12 OAG38576.1 - 0.016 14.8 1.3 0.029 13.9 1.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1295) An_peroxidase PF03098.15 OAG38577.1 - 6.9e-39 133.8 0.0 1.9e-27 96.0 0.0 3.3 1 1 1 2 2 2 2 Animal haem peroxidase Imm43 PF15570.6 OAG38577.1 - 0.0067 16.4 0.1 0.017 15.1 0.1 1.6 1 0 0 1 1 1 1 Immunity protein 43 DUF913 PF06025.12 OAG38578.1 - 4.2e-98 328.7 0.0 4.2e-98 328.7 0.0 5.7 6 1 0 6 6 6 1 Domain of Unknown Function (DUF913) HECT PF00632.25 OAG38578.1 - 5.1e-92 308.6 0.0 1.2e-91 307.4 0.0 1.6 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF908 PF06012.12 OAG38578.1 - 8.6e-70 235.9 0.0 8.6e-70 235.9 0.0 2.6 3 0 0 3 3 3 1 Domain of Unknown Function (DUF908) UBM PF14377.6 OAG38578.1 - 1.1e-23 81.8 14.1 4.2e-08 32.4 0.3 3.8 3 0 0 3 3 3 3 Ubiquitin binding region Ribosomal_L7Ae PF01248.26 OAG38578.1 - 1.7e-19 69.3 0.6 3.8e-19 68.2 0.6 1.5 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family UBA PF00627.31 OAG38578.1 - 0.1 12.5 0.0 0.24 11.3 0.0 1.7 1 0 0 1 1 1 0 UBA/TS-N domain HALZ PF02183.18 OAG38579.1 - 5.6e-05 23.3 2.3 0.53 10.5 0.0 3.0 2 1 0 2 2 2 2 Homeobox associated leucine zipper Cnd1 PF12717.7 OAG38579.1 - 0.0025 17.9 4.2 0.35 10.9 0.1 3.1 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 OAG38579.1 - 0.0027 16.3 0.7 0.013 14.1 0.7 2.3 1 1 0 1 1 1 1 Adaptin N terminal region CLASP_N PF12348.8 OAG38579.1 - 0.0046 16.5 0.1 0.14 11.7 0.0 2.5 2 1 0 2 2 2 1 CLASP N terminal APG6_N PF17675.1 OAG38579.1 - 0.0052 17.3 7.1 0.019 15.5 7.1 2.0 1 0 0 1 1 1 1 Apg6 coiled-coil region TPR_MLP1_2 PF07926.12 OAG38579.1 - 0.0094 16.0 6.6 0.04 14.0 6.6 2.1 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein DivIC PF04977.15 OAG38579.1 - 0.01 15.6 11.8 0.37 10.6 4.0 3.0 2 1 1 3 3 3 0 Septum formation initiator HEAT PF02985.22 OAG38579.1 - 0.035 14.4 0.2 28 5.3 0.2 4.2 4 0 0 4 4 4 0 HEAT repeat Syntaxin PF00804.25 OAG38579.1 - 0.051 13.2 3.6 0.15 11.7 3.6 1.7 1 0 0 1 1 1 0 Syntaxin bZIP_1 PF00170.21 OAG38579.1 - 0.069 13.3 9.2 1.5 9.0 3.5 2.9 2 0 0 2 2 2 0 bZIP transcription factor Golgin_A5 PF09787.9 OAG38579.1 - 0.076 12.5 5.9 0.15 11.5 5.9 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 NRBF2 PF08961.10 OAG38579.1 - 0.093 12.3 7.7 0.65 9.6 0.7 2.6 1 1 1 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator Vac14_Fab1_bd PF12755.7 OAG38579.1 - 0.097 13.3 0.0 50 4.6 0.0 3.7 2 1 1 3 3 3 0 Vacuolar 14 Fab1-binding region UPF0242 PF06785.11 OAG38579.1 - 0.62 10.1 4.7 1.9 8.5 4.7 1.8 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Atg14 PF10186.9 OAG38579.1 - 0.72 8.9 5.2 0.68 9.0 4.0 1.6 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Spc7 PF08317.11 OAG38579.1 - 0.94 8.3 8.3 1.9 7.3 8.3 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein Cep57_CLD_2 PF14197.6 OAG38579.1 - 1.4 9.0 14.7 0.51 10.5 6.2 3.2 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 ADIP PF11559.8 OAG38579.1 - 1.5 8.9 8.4 4.8 7.2 8.4 1.8 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding Mod_r PF07200.13 OAG38579.1 - 1.5 8.9 7.7 3.6 7.7 5.3 2.3 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Spc24 PF08286.11 OAG38579.1 - 3.8 7.8 5.5 24 5.2 0.1 2.8 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 TSC22 PF01166.18 OAG38579.1 - 5.4 7.4 5.2 13 6.1 1.4 2.6 2 0 0 2 2 2 0 TSC-22/dip/bun family JIP_LZII PF16471.5 OAG38579.1 - 6.2 7.1 7.9 9 6.5 1.6 2.7 1 1 1 2 2 2 0 JNK-interacting protein leucine zipper II TMF_DNA_bd PF12329.8 OAG38579.1 - 6.8 6.8 10.8 2.7 8.1 6.9 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding WD40 PF00400.32 OAG38580.1 - 1.8e-48 161.5 31.1 1.7e-07 31.8 0.2 9.1 8 1 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG38580.1 - 4.4e-11 42.9 0.0 0.11 12.8 0.1 5.5 4 2 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OAG38580.1 - 2.5e-05 23.1 0.0 0.0016 17.2 0.0 3.2 3 1 0 3 3 3 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 OAG38580.1 - 4.4e-05 22.4 0.1 1 8.0 0.0 3.2 3 0 0 3 3 3 3 Nup133 N terminal like bZIP_2 PF07716.15 OAG38580.1 - 0.0082 16.2 0.4 0.017 15.2 0.4 1.5 1 0 0 1 1 1 1 Basic region leucine zipper DivIC PF04977.15 OAG38580.1 - 0.12 12.1 0.2 0.22 11.3 0.2 1.3 1 0 0 1 1 1 0 Septum formation initiator bZIP_1 PF00170.21 OAG38580.1 - 0.16 12.1 0.4 0.36 11.0 0.4 1.5 1 0 0 1 1 1 0 bZIP transcription factor DUF5595 PF18077.1 OAG38580.1 - 0.22 11.6 0.3 0.38 10.9 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5595) CPSase_L_D2 PF02786.17 OAG38582.1 - 2.2e-54 184.2 0.0 4.1e-54 183.3 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.19 OAG38582.1 - 1.6e-34 118.2 0.0 5.2e-34 116.6 0.0 1.9 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_carb_N PF00289.22 OAG38582.1 - 2e-27 95.9 0.0 4.4e-27 94.8 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_lipoyl PF00364.22 OAG38582.1 - 1.4e-11 44.0 3.8 1.4e-11 44.0 3.8 2.6 3 1 0 3 3 2 1 Biotin-requiring enzyme ATP-grasp PF02222.22 OAG38582.1 - 1.1e-06 28.3 0.1 2.1e-06 27.4 0.1 1.3 1 0 0 1 1 1 1 ATP-grasp domain RnfC_N PF13375.6 OAG38582.1 - 0.0001 22.2 0.1 0.00034 20.5 0.0 1.9 2 0 0 2 2 2 1 RnfC Barrel sandwich hybrid domain Dala_Dala_lig_C PF07478.13 OAG38582.1 - 0.00019 21.0 0.0 0.00036 20.1 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus DUF2118 PF09891.9 OAG38582.1 - 0.00035 20.6 0.2 0.00076 19.5 0.2 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2118) ATP-grasp_3 PF02655.14 OAG38582.1 - 0.0018 18.3 0.0 0.0035 17.4 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 OAG38582.1 - 0.0051 16.6 0.4 0.077 12.8 0.0 2.5 2 0 0 2 2 2 1 Biotin-lipoyl like ATPgrasp_ST PF14397.6 OAG38582.1 - 0.047 12.9 0.0 0.17 11.1 0.0 1.8 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp PIN_6 PF17146.4 OAG38582.1 - 0.067 13.7 0.1 0.22 12.0 0.1 1.8 1 0 0 1 1 1 0 PIN domain of ribonuclease ATPgrasp_Ter PF15632.6 OAG38582.1 - 0.079 12.7 0.0 0.23 11.2 0.0 1.7 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon DUF1997 PF09366.10 OAG38582.1 - 0.17 12.0 0.1 0.54 10.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1997) Carboxyl_trans PF01039.22 OAG38583.1 - 1.9e-68 231.3 0.0 3.3e-68 230.5 0.0 1.3 1 1 0 1 1 1 1 Carboxyl transferase domain BCDHK_Adom3 PF10436.9 OAG38584.1 - 9e-46 155.7 0.0 1.3e-45 155.1 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 OAG38584.1 - 5.6e-11 42.9 0.0 4e-10 40.2 0.0 2.3 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 OAG38584.1 - 0.11 12.4 0.0 0.61 10.1 0.0 2.1 1 1 0 1 1 1 0 Histidine kinase-like ATPase domain Epimerase PF01370.21 OAG38585.1 - 5.4e-10 39.2 0.2 7.8e-09 35.3 0.2 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 OAG38585.1 - 2e-07 31.1 0.0 2.9e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 OAG38585.1 - 5.3e-07 28.9 0.0 2.2e-06 26.9 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 OAG38585.1 - 2.5e-06 27.2 0.1 3.8e-06 26.6 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family TrkA_N PF02254.18 OAG38585.1 - 0.00086 19.6 0.2 0.0015 18.7 0.2 1.4 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_2 PF03446.15 OAG38585.1 - 0.0069 16.6 0.0 0.011 15.9 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 OAG38585.1 - 0.012 15.7 0.1 0.023 14.8 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 OAG38585.1 - 0.012 15.9 0.1 0.034 14.4 0.1 1.8 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Polysacc_synt_2 PF02719.15 OAG38585.1 - 0.022 13.9 0.0 0.038 13.1 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein ApbA PF02558.16 OAG38585.1 - 0.029 14.0 0.0 0.047 13.3 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA GDP_Man_Dehyd PF16363.5 OAG38585.1 - 0.083 12.3 0.0 0.57 9.5 0.0 2.0 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase AlaDh_PNT_C PF01262.21 OAG38585.1 - 0.089 12.1 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DIOX_N PF14226.6 OAG38586.1 - 8.9e-16 58.7 0.0 2e-15 57.6 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OAG38586.1 - 3.7e-13 49.8 0.0 7.6e-13 48.8 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily NP1-WLL PF11733.8 OAG38586.1 - 0.26 11.0 0.7 21 4.8 0.2 2.2 2 0 0 2 2 2 0 Non-capsid protein NP1 MFS_1 PF07690.16 OAG38587.1 - 7.8e-28 97.4 37.6 1.1e-27 96.9 37.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily PMP1_2 PF08114.11 OAG38587.1 - 0.0096 15.6 0.1 0.044 13.5 0.1 2.1 1 0 0 1 1 1 1 ATPase proteolipid family Zn_clus PF00172.18 OAG38588.1 - 2.8e-10 40.1 9.2 4.8e-10 39.4 9.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_6 PF12697.7 OAG38589.1 - 6.2e-14 53.1 0.2 8.8e-14 52.6 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAG38589.1 - 2e-06 27.6 0.0 8.9e-06 25.5 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF3089 PF11288.8 OAG38589.1 - 0.057 13.0 0.0 0.13 11.8 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3089) Chlorophyllase2 PF12740.7 OAG38589.1 - 0.24 10.3 0.2 0.36 9.7 0.0 1.3 2 0 0 2 2 2 0 Chlorophyllase enzyme MmgE_PrpD PF03972.14 OAG38590.1 - 4e-109 365.1 0.4 4.9e-109 364.8 0.4 1.0 1 0 0 1 1 1 1 MmgE/PrpD family MFS_1 PF07690.16 OAG38591.1 - 6.1e-13 48.4 29.2 6.1e-13 48.4 29.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_2_4 PF16082.5 OAG38591.1 - 1.9 8.3 6.6 9.2 6.1 0.1 2.8 2 1 0 2 2 2 0 Bacteriophage holin family, superfamily II-like Helitron_like_N PF14214.6 OAG38593.1 - 4.1e-37 128.3 2.8 4.5e-37 128.1 1.5 1.8 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.14 OAG38593.1 - 4e-29 101.9 0.1 5e-24 85.1 0.0 2.5 2 1 0 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 OAG38593.1 - 3.6e-13 49.7 0.0 2.1e-12 47.2 0.0 2.2 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.6 OAG38593.1 - 1.2e-07 32.2 0.0 3.8e-07 30.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 OAG38593.1 - 0.00034 20.4 0.2 0.00083 19.1 0.2 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.14 OAG38593.1 - 0.0025 15.9 0.1 0.029 12.3 0.1 2.1 2 0 0 2 2 2 1 Helicase AAA_11 PF13086.6 OAG38593.1 - 0.0046 16.8 0.2 1 9.1 0.0 2.7 1 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 OAG38593.1 - 0.0083 16.4 0.0 0.026 14.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain Helicase_RecD PF05127.14 OAG38593.1 - 0.031 14.1 0.0 0.083 12.7 0.0 1.7 1 0 0 1 1 1 0 Helicase FAD_binding_2 PF00890.24 OAG38595.1 - 1.1e-37 130.2 6.4 1.5e-36 126.4 6.4 2.0 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 OAG38595.1 - 8.6e-07 28.5 0.4 0.00017 20.9 0.4 3.1 2 2 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAG38595.1 - 1.1e-05 25.1 1.7 2.4e-05 24.1 1.7 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 OAG38595.1 - 5.3e-05 22.8 2.5 5.3e-05 22.8 2.5 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase HI0933_like PF03486.14 OAG38595.1 - 0.00013 20.9 2.3 0.0002 20.2 0.4 2.3 3 0 0 3 3 3 1 HI0933-like protein AlaDh_PNT_C PF01262.21 OAG38595.1 - 0.001 18.4 0.1 0.001 18.4 0.1 2.0 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 OAG38595.1 - 0.0016 17.7 0.0 0.0078 15.5 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OAG38595.1 - 0.004 16.3 5.6 0.0097 15.0 1.0 3.1 3 1 0 3 3 3 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 OAG38595.1 - 0.0064 15.6 0.1 0.01 14.9 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 OAG38595.1 - 0.0082 16.3 1.1 0.022 14.9 0.3 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 OAG38595.1 - 0.041 14.5 0.2 0.11 13.1 0.2 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 OAG38595.1 - 0.067 13.6 0.0 0.15 12.5 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Thi4 PF01946.17 OAG38595.1 - 0.27 10.5 0.0 0.27 10.5 0.0 1.8 2 0 0 2 2 2 0 Thi4 family CLN3 PF02487.17 OAG38596.1 - 2.6e-162 540.4 2.3 3e-162 540.2 2.3 1.0 1 0 0 1 1 1 1 CLN3 protein MFS_1 PF07690.16 OAG38596.1 - 0.00088 18.3 5.6 0.0081 15.1 0.8 3.1 2 1 1 3 3 3 2 Major Facilitator Superfamily Rxt3 PF08642.10 OAG38597.1 - 3.9e-28 98.8 0.0 5.7e-27 95.0 0.0 2.6 1 1 0 1 1 1 1 Histone deacetylation protein Rxt3 LCCL PF03815.19 OAG38597.1 - 0.00057 19.9 0.0 0.0041 17.2 0.0 2.1 1 1 0 1 1 1 1 LCCL domain vATP-synt_E PF01991.18 OAG38600.1 - 3.7e-65 219.1 12.3 4.4e-65 218.8 12.3 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit Peptidase_M61 PF05299.12 OAG38600.1 - 0.16 12.4 0.3 0.68 10.4 0.0 2.1 1 1 2 3 3 3 0 M61 glycyl aminopeptidase DUF3574 PF12098.8 OAG38600.1 - 0.2 11.5 1.7 0.32 10.8 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3574) Hydantoinase_A PF01968.18 OAG38600.1 - 0.48 9.6 4.1 2.9 7.1 4.1 2.0 1 1 0 1 1 1 0 Hydantoinase/oxoprolinase Mg_trans_NIPA PF05653.14 OAG38601.1 - 1.8e-15 56.8 12.0 5e-08 32.4 1.8 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA PUNUT PF16913.5 OAG38601.1 - 2.6e-05 23.6 0.2 2.6e-05 23.6 0.2 2.1 2 0 0 2 2 2 1 Purine nucleobase transmembrane transport EamA PF00892.20 OAG38601.1 - 0.0051 17.0 2.9 0.0051 17.0 2.9 3.5 3 2 0 3 3 3 1 EamA-like transporter family K1 PF02960.14 OAG38601.1 - 0.061 13.4 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 K1 glycoprotein TMEM72 PF16054.5 OAG38601.1 - 0.4 10.4 3.4 1.8 8.2 0.8 2.4 2 0 0 2 2 2 0 Transmembrane protein family 72 DUF5315 PF17242.2 OAG38602.1 - 2.4e-22 78.5 3.0 2.4e-22 78.5 3.0 1.8 2 0 0 2 2 2 1 Disordered region of unknown function (DUF5315) DUF4619 PF15398.6 OAG38602.1 - 0.029 13.9 1.0 0.056 13.0 1.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4619) DUF3199 PF11436.8 OAG38602.1 - 0.035 14.1 0.1 0.055 13.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3199) Ribosom_S12_S23 PF00164.25 OAG38603.1 - 6.3e-51 170.8 0.7 8.2e-51 170.4 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 CTP_transf_like PF01467.26 OAG38604.1 - 2.2e-29 102.5 0.0 4.4e-29 101.5 0.0 1.5 1 0 0 1 1 1 1 Cytidylyltransferase-like Arena_RNA_pol PF06317.11 OAG38604.1 - 0.23 8.6 0.1 0.31 8.2 0.1 1.0 1 0 0 1 1 1 0 Arenavirus RNA polymerase PP2C PF00481.21 OAG38605.1 - 8.5e-81 271.4 0.0 1.5e-80 270.6 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C Acetyltransf_1 PF00583.25 OAG38605.1 - 2.1e-14 53.7 0.0 4.5e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OAG38605.1 - 6.1e-08 33.0 0.0 1.4e-07 31.9 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain He_PIG PF05345.12 OAG38605.1 - 9.6e-08 32.1 18.5 0.0028 17.8 1.5 4.7 4 0 0 4 4 4 2 Putative Ig domain Acetyltransf_10 PF13673.7 OAG38605.1 - 1.4e-06 28.2 0.0 2.9e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAG38605.1 - 8.7e-05 22.4 0.2 0.00029 20.8 0.0 1.9 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_6 PF13480.7 OAG38605.1 - 0.0014 18.8 0.0 0.0031 17.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain SUR7 PF06687.12 OAG38606.1 - 7.9e-36 123.7 5.7 1e-35 123.3 5.7 1.1 1 0 0 1 1 1 1 SUR7/PalI family DUF373 PF04123.13 OAG38606.1 - 0.009 15.5 4.6 0.015 14.8 4.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF373) Hum_adeno_E3A PF05393.11 OAG38606.1 - 0.094 12.7 0.0 0.34 10.9 0.0 2.0 2 0 0 2 2 2 0 Human adenovirus early E3A glycoprotein Fig1 PF12351.8 OAG38606.1 - 9.6 6.1 15.2 0.28 11.1 9.0 1.6 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 Mannitol_dh_C PF08125.13 OAG38607.1 - 1.6e-43 149.0 0.0 2.6e-43 148.3 0.0 1.4 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.23 OAG38607.1 - 7.2e-22 78.2 0.7 3.5e-21 75.9 0.1 2.2 2 1 1 3 3 3 1 Mannitol dehydrogenase Rossmann domain 3HCDH_N PF02737.18 OAG38607.1 - 0.00063 19.7 1.5 0.0059 16.5 0.1 2.9 4 0 0 4 4 4 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 OAG38607.1 - 0.00092 18.8 0.7 0.0024 17.5 0.3 1.9 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.16 OAG38607.1 - 0.0049 16.5 0.1 0.14 11.8 0.0 2.3 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA NAD_binding_10 PF13460.6 OAG38607.1 - 0.027 14.3 1.4 12 5.8 0.4 3.1 2 1 0 2 2 2 0 NAD(P)H-binding NAD_Gly3P_dh_N PF01210.23 OAG38607.1 - 0.043 13.8 0.3 4.6 7.2 0.1 3.1 2 1 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UPF0052 PF01933.18 OAG38607.1 - 0.088 12.0 0.4 0.17 11.1 0.4 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0052 Pkinase PF00069.25 OAG38608.1 - 1.5e-10 40.9 0.0 6.7e-07 28.9 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAG38608.1 - 0.027 13.8 0.0 0.21 10.8 0.0 2.0 2 0 0 2 2 2 0 Protein tyrosine kinase DUF3425 PF11905.8 OAG38609.1 - 3.7e-13 49.5 0.1 8.1e-13 48.4 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Zn_clus PF00172.18 OAG38609.1 - 4.2e-07 30.0 5.8 7.6e-07 29.2 5.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.25 OAG38610.1 - 5.1e-25 88.1 0.0 7.3e-25 87.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG38610.1 - 3.6e-20 72.5 0.0 7.6e-20 71.5 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase GCV_T PF01571.21 OAG38610.1 - 0.12 11.8 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Aminomethyltransferase folate-binding domain KR PF08659.10 OAG38610.1 - 0.12 12.3 0.1 0.23 11.4 0.1 1.4 1 0 0 1 1 1 0 KR domain ECH_1 PF00378.20 OAG38611.1 - 8.4e-46 156.3 0.0 1.4e-45 155.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAG38611.1 - 1.4e-27 97.1 0.1 4.5e-23 82.3 0.2 2.1 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase SRF-TF PF00319.18 OAG38612.1 - 3.3e-21 74.5 0.1 4.7e-21 74.0 0.1 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) adh_short PF00106.25 OAG38613.1 - 7.2e-07 28.9 0.0 0.015 14.8 0.0 2.4 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAG38613.1 - 0.0096 15.5 0.0 0.057 13.0 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Tetraspanin PF00335.20 OAG38614.1 - 2.3e-05 24.2 13.5 0.00022 21.0 14.7 1.9 1 1 1 2 2 2 1 Tetraspanin family Ferric_reduct PF01794.19 OAG38614.1 - 0.0022 18.1 5.8 0.0053 16.9 3.8 2.0 2 0 0 2 2 2 1 Ferric reductase like transmembrane component Fungal_trans_2 PF11951.8 OAG38615.1 - 1.3e-09 37.3 2.6 1.9e-09 36.8 2.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG38615.1 - 4.4e-06 26.7 10.0 8.7e-06 25.8 10.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DbpA PF03880.15 OAG38616.1 - 0.0049 16.8 0.0 0.013 15.5 0.0 1.7 1 0 0 1 1 1 1 DbpA RNA binding domain Peptidase_S49_N PF08496.10 OAG38617.1 - 0.002 18.2 10.1 0.0048 17.0 5.2 2.2 2 0 0 2 2 2 1 Peptidase family S49 N-terminal zf-C3HC4_3 PF13920.6 OAG38617.1 - 0.27 11.1 5.0 1.5 8.8 2.6 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) U1snRNP70_N PF12220.8 OAG38617.1 - 5.7 7.7 13.9 20 5.9 0.7 3.0 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF2046 PF09755.9 OAG38618.1 - 0.0037 16.5 1.2 0.066 12.4 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein H4 (DUF2046) DUF1640 PF07798.11 OAG38618.1 - 0.02 15.0 5.6 0.23 11.5 1.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) APG6_N PF17675.1 OAG38618.1 - 0.051 14.1 6.7 0.067 13.7 2.3 2.2 2 0 0 2 2 2 0 Apg6 coiled-coil region CENP-F_N PF10481.9 OAG38618.1 - 0.055 13.1 10.9 0.1 12.3 10.9 1.4 1 0 0 1 1 1 0 Cenp-F N-terminal domain Cnn_1N PF07989.11 OAG38618.1 - 0.12 12.5 3.9 0.17 12.1 1.2 2.2 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 DUF4140 PF13600.6 OAG38618.1 - 0.15 12.5 7.5 0.46 10.9 2.2 2.6 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) HIP1_clath_bdg PF16515.5 OAG38618.1 - 0.44 11.2 12.4 2.2 9.0 4.5 2.6 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Csm1_N PF18504.1 OAG38618.1 - 0.48 10.8 8.3 0.3 11.5 3.1 2.3 2 0 0 2 2 2 0 Csm1 N-terminal domain DUF3450 PF11932.8 OAG38618.1 - 0.83 8.9 8.0 0.46 9.7 3.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) SlyX PF04102.12 OAG38618.1 - 0.84 10.3 7.0 6.9 7.4 2.5 2.4 2 0 0 2 2 2 0 SlyX FlaC_arch PF05377.11 OAG38618.1 - 1.3 9.5 4.0 1.1 9.7 0.2 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) HALZ PF02183.18 OAG38618.1 - 1.3 9.3 6.7 0.34 11.2 2.1 2.3 2 0 0 2 2 2 0 Homeobox associated leucine zipper DegS PF05384.11 OAG38618.1 - 2.3 7.7 10.0 0.3 10.6 5.0 1.9 2 0 0 2 2 2 0 Sensor protein DegS DivIC PF04977.15 OAG38618.1 - 4.4 7.1 10.6 2.1 8.2 5.8 2.3 2 0 0 2 2 2 0 Septum formation initiator GreA_GreB_N PF03449.15 OAG38618.1 - 4.5 7.5 10.6 0.32 11.2 4.6 2.0 2 0 0 2 2 2 0 Transcription elongation factor, N-terminal Calc_CGRP_IAPP PF00214.19 OAG38618.1 - 9.8 6.6 9.7 0.85 10.0 1.2 2.4 2 0 0 2 2 2 0 Calcitonin / CGRP / IAPP family AIM5 PF17050.5 OAG38619.1 - 1.4e-19 70.7 0.9 2.8e-19 69.7 0.9 1.5 1 0 0 1 1 1 1 Altered inheritance of mitochondria 5 Apolipoprotein PF01442.18 OAG38619.1 - 0.0035 17.2 2.1 0.0064 16.4 2.1 1.4 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF3865 PF12981.7 OAG38619.1 - 0.044 13.7 0.2 0.062 13.2 0.2 1.1 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3865) MT0933_antitox PF14013.6 OAG38619.1 - 0.062 13.6 7.6 0.13 12.6 7.6 1.5 1 0 0 1 1 1 0 MT0933-like antitoxin protein RapA_C PF12137.8 OAG38619.1 - 0.063 12.3 0.5 0.12 11.4 0.3 1.5 1 1 1 2 2 2 0 RNA polymerase recycling family C-terminal YtxH PF12732.7 OAG38619.1 - 1.6 9.3 12.8 0.07 13.7 3.1 2.7 2 1 1 3 3 3 0 YtxH-like protein AMP-binding PF00501.28 OAG38620.1 - 6.8e-73 245.7 0.0 9e-73 245.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG38620.1 - 1.7e-15 57.8 0.1 6.1e-15 56.0 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Ribosomal_L17 PF01196.19 OAG38621.1 - 2.3e-29 102.2 0.0 3.8e-29 101.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L17 VasI PF11319.8 OAG38621.1 - 0.0089 15.7 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 Type VI secretion system VasI, EvfG, VC_A0118 HEM4 PF02602.15 OAG38621.1 - 0.036 13.4 0.1 0.057 12.8 0.1 1.3 1 0 0 1 1 1 0 Uroporphyrinogen-III synthase HemD EssA PF10661.9 OAG38621.1 - 0.41 10.5 6.1 0.83 9.5 6.1 1.5 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA IF-2B PF01008.17 OAG38622.1 - 1.7e-41 142.3 0.0 1e-38 133.2 0.0 2.2 1 1 0 1 1 1 1 Initiation factor 2 subunit family NIF PF03031.18 OAG38623.1 - 4.5e-58 195.5 0.0 6.4e-58 194.9 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase EamA PF00892.20 OAG38624.1 - 5.4e-11 42.8 24.9 1.4e-06 28.5 8.6 3.2 3 0 0 3 3 3 3 EamA-like transporter family SUZ PF12752.7 OAG38625.1 - 2.2e-14 53.9 0.8 2.2e-14 53.9 0.8 5.1 4 0 0 4 4 4 1 SUZ domain R3H PF01424.22 OAG38625.1 - 3.2e-05 23.8 0.0 8e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 R3H domain zf-CCHC_3 PF13917.6 OAG38626.1 - 0.00046 20.1 0.5 0.00084 19.3 0.5 1.4 1 0 0 1 1 1 1 Zinc knuckle cwf18 PF08315.12 OAG38627.1 - 2.1e-42 145.0 6.8 2.1e-42 145.0 6.8 1.9 2 1 0 2 2 2 1 cwf18 pre-mRNA splicing factor PPR_2 PF13041.6 OAG38628.1 - 8.1e-08 32.3 0.0 0.05 13.8 0.0 4.0 3 1 1 4 4 4 3 PPR repeat family PPR_long PF17177.4 OAG38628.1 - 1.8e-05 24.2 0.1 0.00077 18.9 0.0 2.5 3 0 0 3 3 3 1 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 OAG38628.1 - 4.8e-05 23.3 2.3 0.28 11.5 0.0 4.5 4 1 0 4 4 4 1 PPR repeat PPR_3 PF13812.6 OAG38628.1 - 0.05 13.7 0.0 3.3 7.8 0.0 3.1 2 1 1 3 3 3 0 Pentatricopeptide repeat domain PHD PF00628.29 OAG38629.1 - 2.3e-05 24.2 4.4 2.3e-05 24.2 4.4 2.2 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.6 OAG38629.1 - 0.2 11.2 5.1 0.15 11.6 1.3 2.6 2 0 0 2 2 2 0 PHD-finger Prok-RING_1 PF14446.6 OAG38629.1 - 0.3 11.0 8.0 0.029 14.3 1.3 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 C1_2 PF03107.16 OAG38629.1 - 0.51 10.7 3.7 0.59 10.5 1.0 2.3 2 0 0 2 2 2 0 C1 domain Torus PF16131.5 OAG38629.1 - 10 6.9 10.1 11 6.8 3.0 3.1 1 1 1 2 2 2 0 Torus domain TFIID-18kDa PF02269.16 OAG38630.1 - 1.5e-17 63.4 0.0 1.8e-16 59.9 0.1 2.2 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit MitMem_reg PF13012.6 OAG38631.1 - 1.6e-18 67.1 0.2 2.7e-18 66.4 0.2 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 OAG38631.1 - 3.9e-18 65.6 0.0 6.1e-18 64.9 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease UPF0172 PF03665.13 OAG38631.1 - 6e-05 23.2 0.2 0.00016 21.8 0.0 1.7 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0172) BTB PF00651.31 OAG38632.1 - 1.2e-24 86.7 0.1 4.8e-12 46.1 0.2 2.8 3 0 0 3 3 3 2 BTB/POZ domain Ank PF00023.30 OAG38632.1 - 6.4e-08 32.7 0.1 0.0014 19.0 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 OAG38632.1 - 7.3e-08 32.9 0.1 1.6e-07 31.8 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OAG38632.1 - 1.4e-07 31.6 0.0 4.5e-07 30.0 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 OAG38632.1 - 3.9e-07 30.5 0.1 1.3e-06 28.9 0.1 2.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG38632.1 - 8.5e-05 22.7 0.3 0.092 13.3 0.0 3.1 2 0 0 2 2 2 1 Ankyrin repeat DUF3342 PF11822.8 OAG38632.1 - 0.0021 18.2 0.0 0.0067 16.6 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3342) Senescence_reg PF04520.13 OAG38632.1 - 0.21 12.4 4.6 0.28 12.0 0.4 2.3 2 0 0 2 2 2 0 Senescence regulator DUF3275 PF11679.8 OAG38632.1 - 0.49 10.4 3.1 1.4 8.8 3.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) DEAD PF00270.29 OAG38633.1 - 1.1e-36 126.3 0.0 1.8e-36 125.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAG38633.1 - 2.5e-25 89.0 0.0 1.4e-23 83.3 0.1 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG38633.1 - 4.9e-07 29.9 0.0 9.3e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 OAG38633.1 - 0.0037 16.7 0.1 0.024 14.0 0.0 2.0 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit Rpr2 PF04032.16 OAG38634.1 - 1.3e-21 76.7 0.2 2.1e-21 76.0 0.2 1.4 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain HNH_5 PF14279.6 OAG38634.1 - 0.088 12.7 1.9 0.57 10.1 1.9 2.1 1 1 1 2 2 2 0 HNH endonuclease Prim_Zn_Ribbon PF08273.12 OAG38634.1 - 0.15 12.4 2.0 0.57 10.5 0.6 2.1 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase BORCS6 PF10157.9 OAG38635.1 - 3.6e-06 27.3 0.1 5.1e-06 26.8 0.1 1.2 1 0 0 1 1 1 1 BLOC-1-related complex sub-unit 6 EzrA PF06160.12 OAG38635.1 - 0.00049 18.4 0.0 0.00065 18.0 0.0 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA DHR10 PF18595.1 OAG38635.1 - 0.0014 18.6 2.5 0.0033 17.5 2.3 1.7 1 1 0 1 1 1 1 Designed helical repeat protein 10 domain DUF1515 PF07439.11 OAG38635.1 - 0.0045 17.0 1.8 0.0078 16.2 1.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1515) DUF1664 PF07889.12 OAG38635.1 - 0.0048 16.9 0.8 0.085 12.9 0.5 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF1664) AIP3 PF03915.13 OAG38635.1 - 0.01 14.9 0.2 0.013 14.6 0.2 1.2 1 0 0 1 1 1 0 Actin interacting protein 3 Laminin_II PF06009.12 OAG38635.1 - 0.021 14.9 1.0 0.021 14.9 1.0 1.6 2 0 0 2 2 2 0 Laminin Domain II MAD PF05557.13 OAG38635.1 - 0.029 12.8 0.2 0.037 12.4 0.2 1.2 1 0 0 1 1 1 0 Mitotic checkpoint protein NOG1_N PF17835.1 OAG38635.1 - 0.032 14.2 0.6 0.14 12.1 0.2 2.0 1 1 0 2 2 2 0 NOG1 N-terminal helical domain T3SSipB PF16535.5 OAG38635.1 - 0.044 14.3 0.0 0.6 10.6 0.1 2.1 1 1 1 2 2 2 0 Type III cell invasion protein SipB BLOC1_2 PF10046.9 OAG38635.1 - 0.048 14.0 2.1 0.97 9.8 0.7 2.5 2 1 0 2 2 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CK2S PF15011.6 OAG38635.1 - 0.048 13.5 0.2 3.3 7.6 0.0 2.3 1 1 1 2 2 2 0 Casein Kinase 2 substrate CorA PF01544.18 OAG38635.1 - 0.048 13.0 3.8 1.6 8.0 5.5 2.0 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein Fzo_mitofusin PF04799.13 OAG38635.1 - 0.05 13.2 0.9 3 7.4 0.1 2.2 1 1 1 2 2 2 0 fzo-like conserved region DUF948 PF06103.11 OAG38635.1 - 0.064 13.5 0.2 0.19 12.0 0.2 1.9 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) CLZ PF16526.5 OAG38635.1 - 0.079 13.3 1.6 18 5.8 0.1 2.8 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Snapin_Pallidin PF14712.6 OAG38635.1 - 0.094 13.1 0.5 0.094 13.1 0.5 2.9 2 1 0 2 2 2 0 Snapin/Pallidin DUF5082 PF16888.5 OAG38635.1 - 0.098 12.9 1.8 0.32 11.3 1.8 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) SseC PF04888.12 OAG38635.1 - 0.11 12.1 0.1 0.19 11.3 0.1 1.4 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Baculo_PEP_C PF04513.12 OAG38635.1 - 0.11 12.6 0.2 0.37 10.8 0.2 1.8 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Vps53_N PF04100.12 OAG38635.1 - 0.14 11.1 0.6 0.21 10.5 0.6 1.2 1 0 0 1 1 1 0 Vps53-like, N-terminal NPV_P10 PF05531.12 OAG38635.1 - 0.15 12.6 0.1 0.83 10.2 0.0 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Syntaxin-6_N PF09177.11 OAG38635.1 - 0.23 12.0 2.2 0.62 10.6 2.2 1.8 1 1 0 1 1 1 0 Syntaxin 6, N-terminal Trimer_CC PF08954.11 OAG38635.1 - 2.9 7.5 10.1 5.3 6.7 0.1 3.7 3 1 0 3 3 3 0 Trimerisation motif Wbp11 PF09429.10 OAG38636.1 - 4.5e-20 71.8 16.4 4.5e-20 71.8 16.4 2.1 2 0 0 2 2 2 1 WW domain binding protein 11 Atg14 PF10186.9 OAG38636.1 - 0.34 10.0 8.7 0.51 9.4 8.7 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF5560 PF17715.1 OAG38636.1 - 2.8 7.4 5.7 6.2 6.2 5.7 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5560) Pkinase PF00069.25 OAG38637.1 - 7.4e-55 186.1 0.1 1.1e-34 120.0 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAG38637.1 - 6.8e-36 123.9 0.0 1.3e-25 90.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 OAG38637.1 - 0.012 14.9 0.0 0.027 13.8 0.0 1.5 1 0 0 1 1 1 0 Kinase-like NCA2 PF08637.10 OAG38637.1 - 0.055 12.6 0.0 0.13 11.4 0.0 1.6 1 0 0 1 1 1 0 ATP synthase regulation protein NCA2 Pkinase_fungal PF17667.1 OAG38637.1 - 0.064 12.0 0.1 0.2 10.4 0.0 1.8 2 0 0 2 2 2 0 Fungal protein kinase APH PF01636.23 OAG38637.1 - 0.075 12.9 1.8 2.2 8.1 0.0 2.6 3 0 0 3 3 3 0 Phosphotransferase enzyme family zf-C2H2 PF00096.26 OAG38638.1 - 5e-08 33.0 13.4 7.4e-05 23.0 2.4 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OAG38638.1 - 3.9e-05 23.9 1.9 3.9e-05 23.9 1.9 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 OAG38638.1 - 0.00033 21.3 11.7 0.048 14.5 1.8 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 OAG38638.1 - 0.0013 19.0 1.1 0.015 15.7 0.2 2.3 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 OAG38638.1 - 0.0053 17.0 3.5 0.14 12.5 0.2 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 OAG38638.1 - 0.09 12.8 0.4 0.09 12.8 0.4 1.9 2 0 0 2 2 2 0 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 OAG38638.1 - 0.26 11.4 4.1 6.5 7.0 0.8 2.4 2 0 0 2 2 2 0 Zinc ribbon domain Zn_ribbon_SprT PF17283.2 OAG38638.1 - 2 8.4 10.4 0.15 12.0 4.7 1.9 2 0 0 2 2 2 0 SprT-like zinc ribbon domain GET2 PF08690.10 OAG38639.1 - 1.6 8.4 4.5 1.9 8.1 4.5 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 DTHCT PF08070.11 OAG38640.1 - 0.044 14.5 8.5 0.073 13.8 8.5 1.3 1 0 0 1 1 1 0 DTHCT (NUC029) region Sugar_tr PF00083.24 OAG38641.1 - 1.5e-79 268.0 28.4 1.8e-79 267.7 28.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG38641.1 - 1.4e-26 93.3 43.4 4.5e-26 91.6 23.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PhyH PF05721.13 OAG38642.1 - 1.7e-16 61.1 0.1 2.2e-16 60.8 0.1 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 OAG38642.1 - 0.045 14.2 0.0 0.087 13.3 0.0 1.5 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase Pkinase PF00069.25 OAG38644.1 - 4.5e-29 101.6 0.0 8.7e-29 100.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG38644.1 - 3.6e-16 59.2 0.0 5.9e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OAG38644.1 - 1.5 8.7 8.9 0.042 13.8 1.0 2.4 3 1 0 3 3 3 0 Phosphotransferase enzyme family CorA PF01544.18 OAG38646.1 - 1e-18 67.7 0.1 2.1e-18 66.7 0.1 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein ABC2_membrane_3 PF12698.7 OAG38646.1 - 0.064 12.4 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein CK2S PF15011.6 OAG38646.1 - 0.18 11.7 8.6 0.16 11.8 0.4 3.2 4 0 0 4 4 4 0 Casein Kinase 2 substrate UTP25 PF06862.12 OAG38647.1 - 8.9e-178 591.9 0.0 1.1e-177 591.5 0.0 1.1 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 DUF2895 PF11444.8 OAG38647.1 - 0.12 11.7 0.0 0.26 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2895) Hydrolase_6 PF13344.6 OAG38648.1 - 4.4e-21 74.9 0.0 9.8e-21 73.8 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OAG38648.1 - 9.8e-19 67.2 0.0 5.6e-18 64.8 0.0 2.2 1 1 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 OAG38648.1 - 0.0056 17.0 0.0 4.2 7.6 0.0 2.6 2 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 OAG38648.1 - 0.074 13.1 0.0 3.1 7.8 0.0 2.3 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Alpha-amylase PF00128.24 OAG38649.1 - 6.2e-19 68.7 2.7 1e-18 68.0 1.0 2.2 2 1 0 2 2 2 1 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.11 OAG38649.1 - 1.9e-13 50.7 0.0 3.4e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 OAG38649.1 - 6.8e-06 25.7 0.0 1.4e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 SMI1_KNR4 PF09346.10 OAG38650.1 - 1.2e-34 119.5 0.0 2e-34 118.9 0.0 1.4 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) Abhydrolase_1 PF00561.20 OAG38650.1 - 0.091 12.4 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold SUKH_5 PF14567.6 OAG38650.1 - 0.13 11.9 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 SMI1-KNR4 cell-wall Bmt2 PF11968.8 OAG38651.1 - 4.7e-66 222.8 0.0 2.5e-34 119.1 0.0 2.5 2 2 0 2 2 2 2 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 Nop14 PF04147.12 OAG38651.1 - 0.094 10.9 7.8 0.13 10.5 7.8 1.3 1 0 0 1 1 1 0 Nop14-like family Zip PF02535.22 OAG38651.1 - 0.64 9.2 3.1 11 5.2 0.5 2.1 2 0 0 2 2 2 0 ZIP Zinc transporter Cwf_Cwc_15 PF04889.12 OAG38651.1 - 2.1 8.0 15.5 4.2 7.0 15.5 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein FAM176 PF14851.6 OAG38651.1 - 4 7.1 6.4 12 5.5 6.4 1.9 1 0 0 1 1 1 0 FAM176 family Kin17_mid PF10357.9 OAG38652.1 - 9.8e-52 174.2 1.4 1.8e-51 173.3 1.4 1.5 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein zf-C2H2_jaz PF12171.8 OAG38652.1 - 0.00025 21.2 0.9 0.00054 20.2 0.9 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OAG38652.1 - 0.001 19.4 2.2 0.0021 18.4 2.2 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 OAG38652.1 - 0.02 15.2 4.3 0.023 15.0 0.3 2.3 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Cytochrom_B558a PF05038.13 OAG38652.1 - 0.11 12.0 2.7 0.19 11.3 2.7 1.5 1 0 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit DIOX_N PF14226.6 OAG38653.1 - 8.8e-20 71.6 0.1 1.8e-19 70.6 0.1 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OAG38653.1 - 2.6e-12 47.1 0.0 5.3e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CorA PF01544.18 OAG38654.1 - 8.1e-46 156.7 0.0 1.4e-45 155.8 0.0 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein YmdB PF13277.6 OAG38654.1 - 0.13 11.6 0.2 0.2 11.0 0.2 1.2 1 0 0 1 1 1 0 YmdB-like protein zf-rbx1 PF12678.7 OAG38655.1 - 4.7e-25 87.6 12.7 7e-25 87.1 12.7 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 OAG38655.1 - 4.3e-17 62.0 10.0 5.7e-17 61.6 10.0 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 OAG38655.1 - 5.8e-06 26.5 15.2 0.0002 21.6 15.2 2.2 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 OAG38655.1 - 7.8e-05 22.4 3.4 7.8e-05 22.4 3.4 2.3 1 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAG38655.1 - 0.0016 18.3 11.5 0.023 14.5 11.5 2.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 OAG38655.1 - 0.12 12.6 8.4 0.49 10.6 8.6 1.8 1 1 1 2 2 2 0 FANCL C-terminal domain zf-C3HC4_3 PF13920.6 OAG38655.1 - 0.3 11.0 10.4 0.65 9.9 4.0 2.4 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAG38655.1 - 0.36 10.9 7.2 1.2 9.2 7.2 1.9 1 1 0 1 1 1 0 RING-type zinc-finger Zn_ribbon_17 PF17120.5 OAG38655.1 - 0.53 9.9 14.7 0.13 11.9 4.8 2.2 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 OAG38655.1 - 1.2 9.0 17.1 98 2.8 17.1 2.5 1 1 0 1 1 1 0 RING-like zinc finger PNRC PF15365.6 OAG38656.1 - 2.1e-08 33.7 6.4 2.1e-08 33.7 6.4 3.5 4 0 0 4 4 4 1 Proline-rich nuclear receptor coactivator motif G10 PF01125.17 OAG38657.1 - 9.8e-65 216.8 1.8 1.1e-64 216.6 1.8 1.1 1 0 0 1 1 1 1 G10 protein Ribosomal_L23eN PF03939.13 OAG38658.1 - 7.9e-27 93.2 10.0 2e-26 92.0 10.0 1.7 1 0 0 1 1 1 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 OAG38658.1 - 1.4e-15 57.4 1.1 1.4e-15 57.4 1.1 1.9 2 0 0 2 2 2 1 Ribosomal protein L23 P2 PF07194.11 OAG38658.1 - 0.023 14.8 0.2 0.044 13.8 0.2 1.5 1 0 0 1 1 1 0 P2 response regulator binding domain Thioredoxin PF00085.20 OAG38659.1 - 4.1e-05 23.5 0.0 6.3e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 OAG38659.1 - 0.27 10.5 0.0 0.44 9.9 0.0 1.3 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family EamA PF00892.20 OAG38660.1 - 0.004 17.3 9.0 0.004 17.3 9.0 2.3 2 0 0 2 2 2 2 EamA-like transporter family KH_1 PF00013.29 OAG38661.1 - 3.1e-10 39.7 0.1 2.4e-07 30.5 0.0 2.6 2 0 0 2 2 2 2 KH domain DUF2431 PF10354.9 OAG38662.1 - 1.7e-61 207.3 0.0 2.6e-61 206.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) Nop25 PF09805.9 OAG38662.1 - 0.11 13.0 0.1 0.11 13.0 0.1 1.8 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) Fungal_trans PF04082.18 OAG38663.1 - 0.0008 18.5 2.4 0.0016 17.5 2.4 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain AMP-binding PF00501.28 OAG38664.1 - 4.4e-87 292.4 0.0 5.7e-87 292.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG38664.1 - 5.6e-12 46.5 0.1 1.8e-11 44.9 0.1 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain SH3_12 PF18129.1 OAG38664.1 - 0.082 13.0 0.4 0.35 11.0 0.0 2.1 2 0 0 2 2 2 0 Xrn1 SH3-like domain p450 PF00067.22 OAG38665.1 - 2.8e-61 207.7 0.0 9e-61 206.0 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 EcKinase PF02958.20 OAG38667.1 - 1.8e-30 106.3 0.0 3.2e-30 105.5 0.0 1.4 1 0 0 1 1 1 1 Ecdysteroid kinase APH PF01636.23 OAG38667.1 - 4.1e-15 56.4 0.2 1.3e-14 54.8 0.2 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family DUF1679 PF07914.11 OAG38667.1 - 1.2e-09 37.6 0.0 1.7e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) Lgl_C PF08596.10 OAG38669.1 - 3.4e-117 391.5 0.0 1.4e-116 389.4 0.0 2.1 3 0 0 3 3 3 1 Lethal giant larvae(Lgl) like, C-terminal ANAPC4_WD40 PF12894.7 OAG38669.1 - 2.1e-08 34.4 0.0 1.5 9.1 0.0 5.6 5 2 0 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OAG38669.1 - 3.9e-06 27.5 0.2 0.067 14.1 0.2 3.8 2 0 0 2 2 2 2 WD domain, G-beta repeat PAR1 PF06521.11 OAG38670.1 - 0.16 11.6 0.0 0.29 10.8 0.0 1.3 1 0 0 1 1 1 0 PAR1 protein SNF2_N PF00176.23 OAG38671.1 - 2.2e-64 217.4 0.4 3.4e-64 216.8 0.4 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OAG38671.1 - 3.9e-13 49.7 0.0 1.2e-12 48.1 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.6 OAG38671.1 - 0.00027 20.8 5.4 0.00027 20.8 5.4 2.1 2 0 0 2 2 2 1 zinc-RING finger domain ERCC3_RAD25_C PF16203.5 OAG38671.1 - 0.043 13.0 0.0 0.088 12.0 0.0 1.5 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase zf-C3HC4 PF00097.25 OAG38671.1 - 0.12 12.3 5.8 0.35 10.8 5.8 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) IBR PF01485.21 OAG38671.1 - 1.9 8.7 6.3 4.8 7.5 1.1 2.9 3 0 0 3 3 3 0 IBR domain, a half RING-finger domain zf-RING_UBOX PF13445.6 OAG38671.1 - 3.6 7.7 5.7 1.7 8.7 2.4 2.2 2 0 0 2 2 2 0 RING-type zinc-finger Ank_4 PF13637.6 OAG38672.1 - 6.3e-26 90.4 8.4 1.5e-06 28.7 0.0 7.0 5 1 1 6 6 6 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 OAG38672.1 - 3.3e-18 66.1 3.3 7.6e-08 32.8 0.1 5.6 4 1 1 5 5 5 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OAG38672.1 - 2.5e-11 43.6 6.5 0.087 13.2 0.0 7.0 7 1 1 8 8 8 3 Ankyrin repeats (many copies) Ank PF00023.30 OAG38672.1 - 2.1e-09 37.4 5.9 1.8 9.1 0.0 6.9 6 0 0 6 6 6 3 Ankyrin repeat NACHT PF05729.12 OAG38672.1 - 2.8e-09 37.1 0.0 9.1e-09 35.4 0.0 1.9 1 0 0 1 1 1 1 NACHT domain Ank_3 PF13606.6 OAG38672.1 - 2.9e-05 24.1 7.1 25 5.9 0.0 8.6 9 1 0 9 9 9 0 Ankyrin repeat AAA_22 PF13401.6 OAG38672.1 - 4.5e-05 23.7 0.0 0.00013 22.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OAG38672.1 - 8.9e-05 22.9 0.0 0.00031 21.2 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain DUF2075 PF09848.9 OAG38672.1 - 0.028 13.7 0.0 0.044 13.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) KAP_NTPase PF07693.14 OAG38672.1 - 0.15 11.3 0.7 0.42 9.8 0.1 1.9 2 1 1 3 3 3 0 KAP family P-loop domain NB-ARC PF00931.22 OAG38672.1 - 0.15 11.2 0.0 0.31 10.2 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain PIF1 PF05970.14 OAG38672.1 - 0.2 10.8 0.0 0.4 9.8 0.0 1.4 1 0 0 1 1 1 0 PIF1-like helicase Asp-B-Hydro_N PF05279.11 OAG38673.1 - 1.8 8.5 25.6 1.9 8.5 12.3 2.2 2 0 0 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region Pkinase PF00069.25 OAG38674.1 - 6.5e-65 219.1 0.0 9e-65 218.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG38674.1 - 1.5e-44 152.3 0.0 2.3e-44 151.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAG38674.1 - 3.3e-12 46.3 0.0 1.8e-07 30.8 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 OAG38674.1 - 0.002 17.5 0.0 0.0039 16.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OAG38674.1 - 0.0026 16.6 0.7 0.0056 15.5 0.7 1.6 1 1 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OAG38674.1 - 0.026 14.4 0.0 0.06 13.3 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family SAM_3 PF18016.1 OAG38675.1 - 0.064 13.1 0.2 0.16 11.8 0.2 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) TPP_enzyme_N PF02776.18 OAG38676.1 - 1.6e-26 92.9 0.0 2.8e-26 92.2 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 OAG38676.1 - 5.3e-21 74.8 0.0 1.3e-20 73.5 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 OAG38676.1 - 9.2e-15 54.7 0.0 7e-14 51.9 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.20 OAG38676.1 - 0.0006 18.9 0.1 0.00093 18.2 0.1 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component p450 PF00067.22 OAG38677.1 - 1.7e-80 271.0 0.0 2.3e-80 270.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_3 PF01494.19 OAG38678.1 - 5.6e-78 262.6 0.0 7e-78 262.3 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 OAG38678.1 - 0.0035 16.6 0.0 0.052 12.8 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG38678.1 - 0.025 13.8 0.0 0.07 12.4 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Polysacc_deac_1 PF01522.21 OAG38678.1 - 0.04 13.8 0.0 9.5 6.1 0.0 2.3 2 0 0 2 2 2 0 Polysaccharide deacetylase Pyr_redox PF00070.27 OAG38678.1 - 0.069 13.7 0.1 0.39 11.3 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 OAG38678.1 - 0.083 12.2 0.0 0.44 9.8 0.0 2.0 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OAG38678.1 - 0.11 12.7 0.2 0.58 10.4 0.2 2.3 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Glyoxalase PF00903.25 OAG38679.1 - 3.3e-13 49.9 0.0 4.5e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 OAG38679.1 - 4.6e-05 24.2 0.0 7.3e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase-like domain p450 PF00067.22 OAG38680.1 - 2.9e-70 237.3 0.0 3.8e-70 236.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_2 PF00703.21 OAG38681.1 - 6e-12 46.2 0.1 1.6e-11 44.8 0.1 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Mannosidase_ig PF17786.1 OAG38681.1 - 5.1e-08 33.4 0.8 4.4e-07 30.4 0.1 2.5 2 0 0 2 2 2 1 Mannosidase Ig/CBM-like domain Ig_mannosidase PF17753.1 OAG38681.1 - 5.5e-06 26.0 0.3 2.9e-05 23.7 0.0 2.3 2 0 0 2 2 2 1 Ig-fold domain Ig_GlcNase PF18368.1 OAG38681.1 - 0.0085 16.2 0.2 0.51 10.5 0.0 2.5 2 0 0 2 2 2 1 Exo-beta-D-glucosaminidase Ig-fold domain Glyco_hydro_2_N PF02837.18 OAG38681.1 - 0.013 15.4 0.0 0.025 14.5 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, sugar binding domain His_Phos_2 PF00328.22 OAG38682.1 - 2.2e-62 211.6 0.0 3.4e-62 211.0 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) GMC_oxred_N PF00732.19 OAG38682.1 - 4.5e-50 170.7 0.0 8.2e-50 169.8 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAG38682.1 - 1.6e-38 132.4 0.1 3.6e-38 131.3 0.1 1.6 1 0 0 1 1 1 1 GMC oxidoreductase MFS_1 PF07690.16 OAG38682.1 - 8.7e-25 87.4 40.2 2.5e-24 85.8 36.2 2.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Fungal_trans PF04082.18 OAG38682.1 - 6.9e-13 48.2 0.0 1.2e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain NAD_binding_8 PF13450.6 OAG38682.1 - 0.00073 19.7 1.4 0.22 11.8 0.6 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Pox_A14 PF05767.12 OAG38682.1 - 0.068 13.3 0.1 2.9 8.1 0.1 2.7 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 FGGY_C PF02782.16 OAG38683.1 - 2.7e-72 242.7 1.1 4.7e-72 241.9 1.1 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 OAG38683.1 - 4.8e-69 232.6 0.0 6.5e-69 232.2 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.20 OAG38683.1 - 0.0093 15.5 0.2 1.3 8.4 0.0 2.2 2 0 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family MIP PF00230.20 OAG38684.1 - 8.4e-55 185.9 3.5 1.1e-54 185.5 3.5 1.1 1 0 0 1 1 1 1 Major intrinsic protein Glyco_hydro_16 PF00722.21 OAG38685.1 - 4.1e-08 32.9 0.2 1.9e-07 30.7 0.0 2.3 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 SAP130_C PF16014.5 OAG38685.1 - 9.3 5.2 12.0 16 4.4 12.0 1.4 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus Fungal_trans PF04082.18 OAG38686.1 - 1.1e-05 24.7 0.3 2.1e-05 23.7 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG38686.1 - 2.2e-05 24.5 8.8 4.8e-05 23.4 8.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ILVD_EDD PF00920.21 OAG38687.1 - 2e-210 699.8 1.2 2.3e-210 699.6 1.2 1.0 1 0 0 1 1 1 1 Dehydratase family Cyclase PF04199.13 OAG38688.1 - 6.6e-14 52.3 0.1 1.1e-13 51.6 0.1 1.4 1 0 0 1 1 1 1 Putative cyclase Vps54 PF07928.12 OAG38689.1 - 4.2e-52 176.1 0.2 4.2e-52 176.1 0.2 2.7 3 0 0 3 3 3 1 Vps54-like protein Vps54_N PF10475.9 OAG38689.1 - 1.8e-06 27.5 1.5 1.8e-06 27.5 1.5 2.2 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex Sec8_exocyst PF04048.14 OAG38689.1 - 0.021 14.7 1.2 0.078 12.9 1.2 2.0 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain LUC7 PF03194.15 OAG38689.1 - 0.021 14.5 3.3 0.019 14.7 1.4 1.9 2 0 0 2 2 2 0 LUC7 N_terminus BLOC1_2 PF10046.9 OAG38689.1 - 1 9.7 4.9 4.4 7.7 1.6 3.4 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FUSC PF04632.12 OAG38689.1 - 3.2 6.2 7.4 6.2 5.2 7.4 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family PAN_4 PF14295.6 OAG38690.1 - 0.0055 16.6 1.8 0.2 11.6 0.4 2.9 2 0 0 2 2 2 2 PAN domain MFS_1 PF07690.16 OAG38691.1 - 2.4e-34 118.8 32.0 2.4e-34 118.8 32.0 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily FAM209 PF15206.6 OAG38691.1 - 0.11 12.2 0.1 0.18 11.6 0.1 1.2 1 0 0 1 1 1 0 FAM209 family OATP PF03137.20 OAG38691.1 - 4.7 5.4 9.1 41 2.3 9.1 2.3 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family MCM PF00493.23 OAG38692.1 - 1.3e-104 348.2 0.2 3.4e-104 346.8 0.0 1.7 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 OAG38692.1 - 1.5e-35 121.7 0.2 3.5e-35 120.6 0.2 1.6 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 OAG38692.1 - 1e-26 93.2 1.1 2.5e-26 91.9 1.1 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 OAG38692.1 - 1.5e-15 57.6 0.5 3.3e-15 56.6 0.5 1.5 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 OAG38692.1 - 1.3e-06 28.0 0.0 0.00026 20.4 0.0 2.3 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 OAG38692.1 - 2.5e-05 24.3 0.0 5.8e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 OAG38692.1 - 0.00031 20.6 0.1 0.0013 18.6 0.0 2.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 OAG38692.1 - 0.03 14.0 0.0 0.97 9.1 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA PF00004.29 OAG38692.1 - 0.12 12.8 0.2 0.54 10.7 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Velvet PF11754.8 OAG38693.1 - 7.5e-06 26.1 0.0 8.3e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 Velvet factor Pkinase PF00069.25 OAG38694.1 - 5.2e-45 153.9 0.0 7.6e-42 143.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAG38694.1 - 5.1e-26 91.5 0.0 9.8e-26 90.6 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAG38694.1 - 0.00046 19.1 0.0 0.00071 18.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OAG38694.1 - 0.013 14.9 0.0 0.02 14.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OAG38694.1 - 0.083 12.2 0.1 0.28 10.5 0.1 1.8 1 1 0 1 1 1 0 Kinase-like DNA_alkylation PF08713.11 OAG38694.1 - 0.19 11.4 0.0 2.9 7.6 0.0 2.1 2 0 0 2 2 2 0 DNA alkylation repair enzyme PhyH PF05721.13 OAG38695.1 - 5.8e-26 92.1 0.1 9.3e-26 91.4 0.1 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) ADH_N PF08240.12 OAG38696.1 - 4.6e-20 71.5 0.3 7.8e-20 70.8 0.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG38696.1 - 6.1e-20 71.5 0.1 1.2e-19 70.6 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 OAG38696.1 - 9.1e-09 35.1 0.3 1.5e-08 34.4 0.3 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 OAG38696.1 - 2.7e-05 25.2 0.0 4.9e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 OAG38696.1 - 0.11 11.8 3.5 0.22 10.8 3.5 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DLH PF01738.18 OAG38698.1 - 1.5e-30 106.4 0.0 1.8e-30 106.1 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 OAG38698.1 - 0.0066 15.9 0.1 0.033 13.7 0.0 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family LIDHydrolase PF10230.9 OAG38698.1 - 0.0085 15.7 0.0 0.011 15.3 0.0 1.1 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase BAAT_C PF08840.11 OAG38698.1 - 0.14 12.0 0.1 8.7 6.2 0.1 2.1 1 1 1 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S15 PF02129.18 OAG38698.1 - 0.18 11.4 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Acyl-CoA_dh_1 PF00441.24 OAG38699.1 - 1e-36 126.4 1.8 1.8e-36 125.6 1.8 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 OAG38699.1 - 1.6e-16 60.2 0.1 4.3e-16 58.9 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 OAG38699.1 - 1.7e-11 44.5 0.3 2.9e-11 43.8 0.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 OAG38699.1 - 1.5e-07 32.1 0.0 1e-06 29.4 0.0 2.3 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain HpaB_N PF11794.8 OAG38699.1 - 0.00031 20.5 0.1 0.0009 19.0 0.1 1.7 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal PLDc PF00614.22 OAG38701.1 - 0.2 11.9 8.1 4.5 7.6 0.3 5.5 6 0 0 6 6 6 0 Phospholipase D Active site motif Metallophos PF00149.28 OAG38702.1 - 1.9e-11 44.9 2.2 4.2e-11 43.7 2.2 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase 5_nucleotid_C PF02872.18 OAG38702.1 - 0.008 16.4 0.0 0.015 15.5 0.0 1.4 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain p450 PF00067.22 OAG38703.1 - 4.1e-49 167.6 0.0 6.6e-49 166.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Aminotran_1_2 PF00155.21 OAG38703.1 - 8.4e-07 28.5 0.0 4e-06 26.3 0.0 2.1 1 1 0 1 1 1 1 Aminotransferase class I and II Methyltransf_23 PF13489.6 OAG38704.1 - 4.8e-16 59.0 0.0 6.6e-16 58.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG38704.1 - 5.9e-09 36.5 0.0 1.4e-08 35.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG38704.1 - 3.3e-07 30.9 0.0 6.2e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG38704.1 - 7.2e-07 29.9 0.0 6.8e-06 26.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG38704.1 - 3.6e-05 23.6 0.0 0.00058 19.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 OAG38704.1 - 0.0048 17.0 0.0 0.0062 16.7 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_4 PF02390.17 OAG38704.1 - 0.022 14.2 0.0 0.037 13.5 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase PrmA PF06325.13 OAG38704.1 - 0.026 13.9 0.0 0.04 13.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 OAG38704.1 - 0.053 13.1 0.0 0.093 12.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain HTH_51 PF18558.1 OAG38704.1 - 0.14 12.1 0.0 1.9 8.4 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain LCCL PF03815.19 OAG38705.1 - 3e-21 75.3 0.1 4.9e-21 74.7 0.1 1.3 1 0 0 1 1 1 1 LCCL domain Zn_clus PF00172.18 OAG38706.1 - 2.6e-07 30.6 7.9 6.3e-07 29.4 7.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 OAG38706.1 - 1.3e-05 24.3 0.1 7.9e-05 21.6 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain CLN6 PF15156.6 OAG38706.1 - 0.017 14.5 0.0 0.026 13.8 0.0 1.1 1 0 0 1 1 1 0 Ceroid-lipofuscinosis neuronal protein 6 CALM_bind PF16025.5 OAG38706.1 - 0.074 13.5 0.0 0.16 12.5 0.0 1.5 1 0 0 1 1 1 0 Calcium-dependent calmodulin binding AMP-binding PF00501.28 OAG38707.1 - 1.5e-86 290.6 0.0 1.9e-86 290.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Cys_Met_Meta_PP PF01053.20 OAG38708.1 - 5.2e-146 486.1 0.0 5.9e-146 485.9 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 OAG38708.1 - 5.6e-10 38.9 0.0 9.1e-10 38.2 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 OAG38708.1 - 5.5e-08 32.5 0.2 1e-07 31.6 0.2 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 OAG38708.1 - 0.00011 21.3 0.2 0.00017 20.7 0.2 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 OAG38708.1 - 0.00051 19.4 0.0 0.00077 18.8 0.0 1.3 1 1 0 1 1 1 1 Beta-eliminating lyase SepSecS PF05889.13 OAG38708.1 - 0.0019 17.0 0.0 0.0027 16.5 0.0 1.2 1 0 0 1 1 1 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Met_gamma_lyase PF06838.11 OAG38708.1 - 0.039 12.5 0.0 0.054 12.0 0.0 1.2 1 0 0 1 1 1 0 Methionine gamma-lyase Dynactin_p22 PF07426.11 OAG38708.1 - 0.24 11.3 0.0 0.38 10.6 0.0 1.2 1 0 0 1 1 1 0 Dynactin subunit p22 MFS_1 PF07690.16 OAG38709.1 - 6.8e-52 176.5 26.0 2.3e-39 135.3 9.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 OAG38709.1 - 5.5e-10 38.4 21.8 6.5e-06 25.0 1.9 3.0 2 1 1 3 3 3 3 MFS/sugar transport protein Sugar_tr PF00083.24 OAG38709.1 - 3e-07 29.7 6.2 3e-07 29.7 6.2 2.7 1 1 1 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 OAG38709.1 - 3.5e-06 25.6 0.2 0.00042 18.7 0.2 2.4 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.7 OAG38709.1 - 0.00034 19.6 5.9 0.0031 16.4 2.1 2.7 2 1 1 3 3 3 1 MFS_1 like family Mem_trans PF03547.18 OAG38709.1 - 0.039 12.3 0.2 0.13 10.6 0.0 1.8 2 0 0 2 2 2 0 Membrane transport protein MerT PF02411.15 OAG38709.1 - 0.063 13.3 0.4 0.063 13.3 0.4 2.7 2 0 0 2 2 2 0 MerT mercuric transport protein PTR2 PF00854.21 OAG38709.1 - 0.26 10.1 2.9 3.8 6.2 0.7 2.3 2 0 0 2 2 2 0 POT family DUF4271 PF14093.6 OAG38709.1 - 6.6 6.6 7.8 18 5.2 0.0 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF4271) MARVEL PF01284.23 OAG38710.1 - 2e-16 60.3 16.8 2.3e-16 60.1 16.8 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF1440 PF07274.12 OAG38710.1 - 0.28 11.5 5.2 0.14 12.5 2.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1440) UL45 PF05473.12 OAG38710.1 - 0.31 10.6 1.1 0.58 9.8 1.1 1.4 1 0 0 1 1 1 0 UL45 protein, carbohydrate-binding C-type lectin-like DUF3611 PF12263.8 OAG38710.1 - 0.33 10.8 6.8 2 8.3 0.1 2.5 1 1 1 3 3 3 0 Protein of unknown function (DUF3611) DUF202 PF02656.15 OAG38710.1 - 5.8 7.4 12.6 0.39 11.2 3.4 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF202) EF-hand_4 PF12763.7 OAG38711.1 - 1.2e-32 112.0 0.0 3.3e-12 46.3 0.0 3.5 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.6 OAG38711.1 - 4.8e-08 33.3 0.0 0.00035 21.0 0.0 4.0 4 0 0 4 4 3 1 EF-hand domain pair EF-hand_1 PF00036.32 OAG38711.1 - 4.1e-07 29.1 0.0 0.28 10.8 0.0 4.7 4 0 0 4 4 4 2 EF hand Spc7 PF08317.11 OAG38711.1 - 0.00036 19.5 38.6 0.0014 17.6 27.8 2.1 1 1 1 2 2 2 2 Spc7 kinetochore protein DUF724 PF05266.14 OAG38711.1 - 0.00051 19.9 10.5 0.00051 19.9 10.5 3.2 1 1 2 3 3 3 1 Protein of unknown function (DUF724) EF-hand_6 PF13405.6 OAG38711.1 - 0.0017 18.1 0.1 30 4.9 0.1 4.5 4 0 0 4 4 4 0 EF-hand domain MbeD_MobD PF04899.12 OAG38711.1 - 0.0029 17.7 16.8 0.029 14.5 3.9 4.4 3 1 2 5 5 4 2 MbeD/MobD like UBA PF00627.31 OAG38711.1 - 0.0039 17.1 0.0 0.0082 16.0 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain Macoilin PF09726.9 OAG38711.1 - 0.0079 14.8 29.7 0.014 14.0 29.7 1.3 1 0 0 1 1 1 1 Macoilin family DUF3584 PF12128.8 OAG38711.1 - 0.12 9.9 33.6 0.18 9.3 33.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) EF-hand_8 PF13833.6 OAG38711.1 - 0.16 11.8 0.2 32 4.5 0.0 3.4 4 0 0 4 4 4 0 EF-hand domain pair Mating_N PF12731.7 OAG38711.1 - 0.36 11.0 4.5 7.5 6.7 1.0 2.5 2 0 0 2 2 2 0 Mating-type protein beta 1 GOLGA2L5 PF15070.6 OAG38711.1 - 0.59 8.7 28.1 0.88 8.1 28.1 1.1 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 APG6_N PF17675.1 OAG38711.1 - 0.59 10.7 44.6 1.2 9.6 18.7 3.0 1 1 2 3 3 3 0 Apg6 coiled-coil region LPP PF04728.13 OAG38711.1 - 0.74 10.3 25.3 0.19 12.1 1.3 4.3 2 1 0 3 3 3 0 Lipoprotein leucine-zipper Lebercilin PF15619.6 OAG38711.1 - 0.76 9.4 40.6 1.4 8.5 40.0 1.7 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease GAS PF13851.6 OAG38711.1 - 1.2 8.5 39.4 3.4 7.0 20.4 2.7 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding PRKG1_interact PF15898.5 OAG38711.1 - 1.4 9.8 35.7 0.046 14.6 13.8 3.8 1 1 2 3 3 3 0 cGMP-dependent protein kinase interacting domain EzrA PF06160.12 OAG38711.1 - 1.4 7.0 26.4 2.6 6.1 26.4 1.3 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Golgin_A5 PF09787.9 OAG38711.1 - 1.8 7.9 39.3 0.04 13.4 23.8 2.2 1 1 1 2 2 2 0 Golgin subfamily A member 5 Csm1_N PF18504.1 OAG38711.1 - 2.2 8.7 34.5 0.16 12.3 2.8 4.4 3 1 1 4 4 4 0 Csm1 N-terminal domain CENP-F_leu_zip PF10473.9 OAG38711.1 - 4.3 7.3 41.2 5.2 7.1 13.7 3.3 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.12 OAG38711.1 - 8.7 6.4 23.4 0.85 9.7 8.6 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) IFT57 PF10498.9 OAG38711.1 - 9 5.1 33.3 0.16 10.9 18.5 2.3 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 Tubulin PF00091.25 OAG38712.1 - 8.9e-54 182.7 0.0 1.4e-53 182.0 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 OAG38712.1 - 2.5e-51 173.1 0.2 4.2e-51 172.4 0.2 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 OAG38712.1 - 0.0015 18.2 0.0 0.0038 16.9 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain Pga1 PF10333.9 OAG38713.1 - 0.00094 19.1 0.0 0.0013 18.6 0.0 1.3 1 0 0 1 1 1 1 GPI-Mannosyltransferase II co-activator Fungal_trans PF04082.18 OAG38714.1 - 1.5e-08 34.1 0.0 2.3e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG38714.1 - 2.9e-05 24.1 15.5 4.7e-05 23.4 15.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dioxygenase_C PF00775.21 OAG38715.1 - 8e-44 149.2 0.1 1.5e-40 138.6 0.1 2.2 1 1 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 OAG38715.1 - 6.6e-27 93.2 0.2 1.1e-26 92.4 0.2 1.4 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 OAG38715.1 - 0.0009 19.5 0.1 0.34 11.2 0.0 2.6 3 0 0 3 3 3 2 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 OAG38715.1 - 0.025 14.6 0.1 9.5 6.3 0.0 3.4 3 0 0 3 3 3 0 CarboxypepD_reg-like domain Lipase_C PF18067.1 OAG38715.1 - 0.083 13.4 0.0 0.22 12.1 0.0 1.7 1 0 0 1 1 1 0 Lipase C-terminal domain PglZ PF08665.12 OAG38715.1 - 0.12 12.4 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 PglZ domain Methyltr_RsmB-F PF01189.17 OAG38716.1 - 1.3e-75 253.5 0.0 2.3e-75 252.7 0.0 1.4 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 OAG38716.1 - 1.8e-07 31.6 0.0 4.9e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF FtsJ PF01728.19 OAG38716.1 - 0.015 15.5 0.0 0.036 14.2 0.0 1.6 1 0 0 1 1 1 0 FtsJ-like methyltransferase Zn_clus PF00172.18 OAG38717.1 - 3.3e-08 33.5 9.3 6.5e-08 32.6 9.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fe_dep_repr_C PF02742.15 OAG38717.1 - 0.018 15.1 0.0 0.063 13.4 0.0 1.9 2 0 0 2 2 2 0 Iron dependent repressor, metal binding and dimerisation domain Glycogen_syn PF05693.13 OAG38718.1 - 0 1065.0 0.0 0 1056.4 0.0 2.0 1 1 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.20 OAG38718.1 - 0.00011 21.8 0.0 0.023 14.2 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 OAG38718.1 - 0.00051 20.5 0.0 0.19 12.2 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 OAG38718.1 - 0.001 19.5 0.1 0.0025 18.3 0.1 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 OAG38718.1 - 0.002 18.1 0.1 0.0042 17.1 0.1 1.6 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Sulfatase PF00884.23 OAG38719.1 - 1.9e-45 155.6 1.3 4.6e-45 154.3 0.3 1.9 1 1 1 2 2 2 1 Sulfatase DUF4976 PF16347.5 OAG38719.1 - 0.0021 18.3 0.3 0.0055 16.9 0.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4976) polyprenyl_synt PF00348.17 OAG38720.1 - 1e-89 300.0 0.0 1.3e-89 299.7 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase XPA_C PF05181.12 OAG38721.1 - 6.2e-26 90.1 2.1 1.3e-25 89.1 2.1 1.5 1 0 0 1 1 1 1 XPA protein C-terminus XPA_N PF01286.18 OAG38721.1 - 3.6e-05 23.7 1.7 3.6e-05 23.7 1.7 1.9 2 0 0 2 2 2 1 XPA protein N-terminal DZR PF12773.7 OAG38721.1 - 0.078 13.0 0.4 2.3 8.3 0.2 2.5 2 0 0 2 2 2 0 Double zinc ribbon zf-C3HC4_3 PF13920.6 OAG38721.1 - 0.096 12.6 1.7 0.31 11.0 0.2 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) ADD_DNMT3 PF17980.1 OAG38721.1 - 0.31 11.1 1.7 0.54 10.3 0.1 2.0 2 0 0 2 2 2 0 Cysteine rich ADD domain in DNMT3 zf-dskA_traR PF01258.17 OAG38721.1 - 1.3 9.0 4.2 1.1e+02 2.9 0.0 3.4 3 0 0 3 3 3 0 Prokaryotic dksA/traR C4-type zinc finger YhfH PF14149.6 OAG38721.1 - 6 6.9 7.3 0.64 10.0 0.1 2.6 3 0 0 3 3 3 0 YhfH-like protein Striatin PF08232.12 OAG38722.1 - 2e-42 145.4 6.3 2e-42 145.4 6.3 1.8 2 0 0 2 2 2 1 Striatin family WD40 PF00400.32 OAG38722.1 - 1.7e-24 85.6 24.8 2.3e-05 25.0 0.1 8.9 9 1 0 9 9 9 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG38722.1 - 1.6e-05 25.1 0.1 1.3 9.4 0.0 5.3 4 1 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OAG38722.1 - 0.0018 18.2 0.0 0.0054 16.6 0.0 1.8 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A DUF4482 PF14818.6 OAG38722.1 - 2.6 8.9 9.0 0.23 12.3 3.9 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4482) 4HBT PF03061.22 OAG38723.1 - 1e-08 35.4 0.1 1.9e-08 34.5 0.1 1.4 1 0 0 1 1 1 1 Thioesterase superfamily adh_short PF00106.25 OAG38724.1 - 3.5e-42 144.1 0.0 4.3e-42 143.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG38724.1 - 7.1e-41 140.3 0.0 8.9e-41 140.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG38724.1 - 0.0048 16.8 0.1 0.035 14.0 0.1 2.0 1 1 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.8 OAG38724.1 - 0.043 13.6 1.1 0.12 12.2 0.0 2.0 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase p450 PF00067.22 OAG38725.1 - 1.3e-53 182.4 0.0 1.4e-33 116.4 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 TRI12 PF06609.13 OAG38726.1 - 2.6e-49 168.2 20.7 3.4e-49 167.8 20.7 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG38726.1 - 3.8e-29 101.7 49.3 3.8e-29 101.7 49.3 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG38726.1 - 9.7e-06 24.7 35.4 0.00016 20.7 17.6 2.7 2 1 0 2 2 2 2 Sugar (and other) transporter SPC12 PF06645.13 OAG38726.1 - 6.6 6.9 9.7 4.5 7.4 1.7 4.0 3 0 0 3 3 3 0 Microsomal signal peptidase 12 kDa subunit (SPC12) Cupin_2 PF07883.11 OAG38727.1 - 8.3e-09 35.0 0.2 1.2e-08 34.5 0.2 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.7 OAG38727.1 - 0.00017 21.3 0.2 0.00021 21.1 0.2 1.2 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.19 OAG38727.1 - 0.00035 20.5 0.1 0.00045 20.1 0.1 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.22 OAG38727.1 - 0.0096 15.5 0.0 0.015 14.9 0.0 1.4 1 1 0 1 1 1 1 Cupin TFIID_30kDa PF03540.13 OAG38727.1 - 0.14 12.1 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID 23-30kDa subunit Ldi PF18566.1 OAG38728.1 - 3.5e-71 240.3 0.0 6e-71 239.5 0.0 1.4 1 1 0 1 1 1 1 Linalool dehydratase/isomerase AA_permease_2 PF13520.6 OAG38729.1 - 1.3e-91 307.6 35.4 1.6e-91 307.3 35.4 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAG38729.1 - 2e-19 69.6 27.2 2.7e-19 69.1 27.2 1.2 1 1 0 1 1 1 1 Amino acid permease Dynamin_N PF00350.23 OAG38730.1 - 7.1e-29 101.0 0.8 2e-28 99.6 0.0 2.2 3 0 0 3 3 3 1 Dynamin family Dynamin_M PF01031.20 OAG38730.1 - 3.4e-24 85.6 0.1 5.6e-24 84.8 0.1 1.4 1 0 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.23 OAG38730.1 - 5.2e-05 23.3 0.0 0.00071 19.6 0.0 2.6 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_21 PF13304.6 OAG38730.1 - 0.0018 18.2 0.3 0.035 13.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system DUF2267 PF10025.9 OAG38730.1 - 0.049 13.9 1.4 3.7 7.9 0.0 3.6 4 0 0 4 4 4 0 Uncharacterized conserved protein (DUF2267) MCM3AP_GANP PF16769.5 OAG38730.1 - 0.05 11.9 0.0 0.099 10.9 0.0 1.6 1 1 0 1 1 1 0 MCM3AP domain of GANP CDT1 PF08839.11 OAG38730.1 - 0.078 13.3 0.6 5.6 7.2 0.1 2.5 2 0 0 2 2 2 0 DNA replication factor CDT1 like AAA_15 PF13175.6 OAG38730.1 - 0.082 12.6 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 OAG38730.1 - 0.084 12.6 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain T3SS_LEE_assoc PF13327.6 OAG38730.1 - 0.097 12.7 0.2 0.36 10.8 0.1 1.9 2 0 0 2 2 2 0 Type III secretion system subunit DUF1690 PF07956.11 OAG38730.1 - 0.93 9.9 6.0 0.66 10.4 0.2 3.1 3 0 0 3 3 3 0 Protein of Unknown function (DUF1690) DUF3405 PF11885.8 OAG38731.1 - 8.5e-130 433.8 0.5 1.1e-129 433.4 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) Catalase PF00199.19 OAG38732.1 - 1.8e-05 24.1 0.0 0.00045 19.4 0.0 2.0 2 0 0 2 2 2 2 Catalase p450 PF00067.22 OAG38733.1 - 9e-65 219.2 0.0 2.4e-64 217.8 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 ADH_zinc_N PF00107.26 OAG38734.1 - 4.3e-15 55.8 0.1 6.8e-15 55.2 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAG38734.1 - 6.1e-10 40.3 0.0 1.1e-09 39.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG38734.1 - 4.9e-08 32.8 0.0 5.5e-07 29.4 0.0 2.4 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.6 OAG38734.1 - 0.0023 17.8 0.6 0.0039 17.1 0.6 1.4 1 0 0 1 1 1 1 NAD(P)H-binding AlaDh_PNT_C PF01262.21 OAG38734.1 - 0.033 13.5 0.2 0.05 12.9 0.2 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NmrA PF05368.13 OAG38734.1 - 0.099 12.2 0.6 0.15 11.6 0.6 1.2 1 0 0 1 1 1 0 NmrA-like family LigB PF02900.18 OAG38735.1 - 6.5e-13 48.4 0.0 1e-12 47.8 0.0 1.2 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase NAD_binding_8 PF13450.6 OAG38736.1 - 5e-07 29.8 0.0 7.4e-06 26.1 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAG38736.1 - 5.4e-07 29.1 0.0 7.8e-06 25.3 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 OAG38736.1 - 2.4e-05 23.0 0.0 0.00012 20.6 0.0 2.0 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OAG38736.1 - 0.00012 21.5 0.3 0.00083 18.7 0.2 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG38736.1 - 0.0027 16.9 0.0 0.011 14.9 0.0 1.8 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 OAG38736.1 - 0.0082 16.1 0.0 0.11 12.5 0.0 2.6 2 1 0 2 2 2 1 FAD-NAD(P)-binding 2-Hacid_dh_C PF02826.19 OAG38736.1 - 0.018 14.4 0.0 0.037 13.4 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 OAG38736.1 - 0.075 13.1 0.0 0.46 10.6 0.0 2.1 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Fungal_trans PF04082.18 OAG38737.1 - 4.3e-22 78.4 1.2 8.5e-22 77.4 1.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG38737.1 - 9.9e-07 28.8 10.5 1.8e-06 28.0 10.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2730 PF10805.8 OAG38737.1 - 0.061 13.4 0.2 0.16 12.1 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) CRM1_repeat PF18777.1 OAG38737.1 - 0.085 12.4 0.1 0.77 9.3 0.0 2.5 2 0 0 2 2 2 0 Chromosome region maintenance or exportin repeat FAD_binding_3 PF01494.19 OAG38738.1 - 2.6e-22 79.6 0.4 1.2e-21 77.3 0.4 1.8 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAG38738.1 - 3.3e-10 40.1 0.2 1.1e-06 28.5 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OAG38738.1 - 4.7e-09 35.8 0.1 7.7e-09 35.1 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 OAG38738.1 - 1.2e-08 34.6 0.7 6.4e-07 28.9 0.2 2.2 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAG38738.1 - 3e-08 34.1 0.1 3.3e-07 30.8 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAG38738.1 - 3.9e-07 29.1 0.1 7.6e-07 28.2 0.1 1.5 1 1 0 1 1 1 1 HI0933-like protein GIDA PF01134.22 OAG38738.1 - 1.1e-06 28.1 0.6 1.4e-06 27.6 0.6 1.3 1 1 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 OAG38738.1 - 6.2e-06 26.4 0.1 1.7e-05 24.9 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 OAG38738.1 - 1.4e-05 24.5 0.5 7.4e-05 22.1 0.1 2.0 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAG38738.1 - 7.4e-05 22.1 0.0 0.00013 21.3 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 OAG38738.1 - 0.00017 20.8 0.2 0.00025 20.2 0.2 1.4 1 1 0 1 1 1 1 Lycopene cyclase protein FAD_oxidored PF12831.7 OAG38738.1 - 0.0002 20.8 0.4 0.00037 20.0 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 OAG38738.1 - 0.0077 15.6 0.0 0.039 13.3 0.0 2.0 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase UDPG_MGDP_dh_N PF03721.14 OAG38738.1 - 0.011 15.3 0.3 0.074 12.6 0.1 2.1 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.16 OAG38738.1 - 0.026 14.2 0.0 0.053 13.2 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 OAG38738.1 - 0.028 14.7 0.1 0.084 13.1 0.1 1.9 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_7 PF13241.6 OAG38738.1 - 0.043 14.2 0.0 0.068 13.6 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding AlaDh_PNT_C PF01262.21 OAG38738.1 - 0.05 12.9 0.1 0.08 12.2 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 OAG38738.1 - 0.07 13.0 0.2 0.18 11.7 0.1 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 OAG38738.1 - 0.11 12.5 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Cu-oxidase_3 PF07732.15 OAG38739.1 - 2.5e-36 124.3 0.6 2.5e-36 124.3 0.6 2.4 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.22 OAG38739.1 - 1.3e-25 90.4 0.0 2.4e-25 89.5 0.0 1.5 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 OAG38739.1 - 1.7e-09 37.5 5.6 1.3e-05 25.0 0.0 3.8 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 OAG38740.1 - 7.4e-22 77.6 0.0 9.9e-22 77.2 0.0 1.2 1 0 0 1 1 1 1 Multicopper oxidase MFS_1 PF07690.16 OAG38741.1 - 5e-45 154.0 31.2 5e-45 154.0 31.2 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG38741.1 - 8.9e-17 61.1 3.1 8.9e-17 61.1 3.1 2.1 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 OAG38741.1 - 2.3e-11 42.9 0.9 3.5e-11 42.3 0.9 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 OAG38741.1 - 1.1e-07 31.5 3.8 1.1e-07 31.5 3.8 2.7 2 2 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 OAG38741.1 - 0.0087 14.4 0.4 0.0087 14.4 0.4 2.7 3 1 0 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family DUF2545 PF10810.8 OAG38741.1 - 0.28 11.3 10.9 0.034 14.3 3.5 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2545) Aldedh PF00171.22 OAG38742.1 - 1.5e-05 23.7 0.0 2.1e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family HMA PF00403.26 OAG38743.1 - 2.1e-09 37.7 0.0 2.8e-09 37.3 0.0 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain Fungal_trans_2 PF11951.8 OAG38744.1 - 8.9e-07 28.0 1.7 9.8e-07 27.9 0.5 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Abhydrolase_3 PF07859.13 OAG38745.1 - 3.2e-10 40.2 0.0 4.4e-09 36.5 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 OAG38745.1 - 5.5e-07 28.8 0.0 1.1e-06 27.8 0.0 1.4 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 OAG38745.1 - 1.8e-05 24.4 0.0 0.00018 21.1 0.0 2.2 1 1 0 1 1 1 1 Prolyl oligopeptidase family Say1_Mug180 PF10340.9 OAG38745.1 - 0.00031 19.7 0.0 0.00044 19.2 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_6 PF12697.7 OAG38745.1 - 0.0061 17.2 2.0 0.015 15.9 2.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family FAD_binding_3 PF01494.19 OAG38746.1 - 3.5e-16 59.4 0.2 1.3e-15 57.5 0.2 1.8 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAG38746.1 - 9.5e-10 38.6 3.7 5.3e-05 23.0 1.4 2.3 1 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 OAG38746.1 - 4.4e-08 33.6 0.5 2.4e-05 24.8 0.2 3.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAG38746.1 - 6.1e-08 32.2 1.2 1.4e-06 27.8 0.3 2.3 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG38746.1 - 1.8e-07 31.3 0.9 5.2e-07 29.8 0.9 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 OAG38746.1 - 1.2e-05 24.6 2.4 4.1e-05 22.8 1.9 1.9 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 OAG38746.1 - 3.7e-05 22.6 0.8 8.9e-05 21.4 0.5 1.6 2 0 0 2 2 2 1 HI0933-like protein Amino_oxidase PF01593.24 OAG38746.1 - 0.00043 19.7 0.3 0.0019 17.6 0.3 2.0 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Thi4 PF01946.17 OAG38746.1 - 0.0012 18.2 0.1 0.0022 17.3 0.1 1.4 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 OAG38746.1 - 0.0017 17.5 0.1 0.0024 17.0 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 OAG38746.1 - 0.0044 16.3 0.2 0.0085 15.4 0.2 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 OAG38746.1 - 0.016 14.5 0.7 0.024 13.9 0.2 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OAG38746.1 - 0.02 14.0 0.3 0.034 13.2 0.3 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein CoA_transf_3 PF02515.17 OAG38746.1 - 0.088 11.9 0.4 0.13 11.3 0.4 1.2 1 0 0 1 1 1 0 CoA-transferase family III FAD_oxidored PF12831.7 OAG38746.1 - 0.2 10.9 1.7 0.41 9.9 1.7 1.6 1 1 0 1 1 1 0 FAD dependent oxidoreductase Trp_halogenase PF04820.14 OAG38746.1 - 0.27 10.0 2.0 1.9 7.2 0.4 2.1 2 0 0 2 2 2 0 Tryptophan halogenase TRI12 PF06609.13 OAG38747.1 - 1e-51 176.1 24.7 2.9e-50 171.3 24.7 2.0 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG38747.1 - 3.9e-31 108.3 48.4 1.9e-28 99.4 47.7 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG38747.1 - 6.7e-09 35.1 11.9 6.7e-09 35.1 11.9 2.1 2 1 0 2 2 2 1 Sugar (and other) transporter p450 PF00067.22 OAG38748.1 - 1.6e-68 231.6 0.0 1.9e-68 231.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 NmrA PF05368.13 OAG38749.1 - 4.8e-28 98.3 0.2 7.1e-28 97.7 0.2 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG38749.1 - 2.2e-21 76.6 0.1 3.1e-21 76.1 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAG38749.1 - 0.00026 20.5 0.5 0.0046 16.5 0.2 2.7 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 OAG38749.1 - 0.044 13.8 0.1 0.081 13.0 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase p450 PF00067.22 OAG38750.1 - 1.9e-63 214.8 0.1 1.5e-50 172.3 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 Alpha-amylase PF00128.24 OAG38751.1 - 5.1e-15 55.9 0.0 6.9e-14 52.1 0.0 2.1 2 0 0 2 2 2 1 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.18 OAG38751.1 - 0.061 13.8 0.0 0.18 12.3 0.0 1.7 1 0 0 1 1 1 0 Alpha amylase, C-terminal all-beta domain AAA_16 PF13191.6 OAG38753.1 - 4.1e-10 40.3 1.8 6.4e-10 39.7 0.1 2.2 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 OAG38753.1 - 1.8e-09 37.7 0.1 1.2e-08 35.0 0.1 2.3 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 OAG38753.1 - 1.1e-06 29.0 0.2 1.3e-05 25.5 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 OAG38753.1 - 3.2e-05 24.5 0.0 0.00023 21.7 0.0 2.6 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 OAG38753.1 - 0.0026 17.7 0.3 0.99 9.3 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA PF00004.29 OAG38753.1 - 0.0041 17.5 0.1 0.21 12.0 0.0 3.3 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 OAG38753.1 - 0.015 15.7 0.2 0.19 12.2 0.0 2.5 2 0 0 2 2 2 0 RNA helicase Baculo_PEP_C PF04513.12 OAG38753.1 - 0.03 14.4 1.4 0.12 12.4 1.4 2.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus ATPase_2 PF01637.18 OAG38753.1 - 0.031 14.2 0.0 0.1 12.5 0.0 1.8 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea Viral_helicase1 PF01443.18 OAG38753.1 - 0.036 13.8 0.0 0.081 12.6 0.0 1.6 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 OAG38753.1 - 0.045 13.5 0.0 0.14 11.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 OAG38753.1 - 0.047 13.1 0.0 0.77 9.1 0.0 2.5 2 0 0 2 2 2 0 Bacterial TniB protein AAA_29 PF13555.6 OAG38753.1 - 0.05 13.3 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 OAG38753.1 - 0.063 12.6 0.0 0.14 11.4 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.6 OAG38753.1 - 0.079 13.1 0.0 0.36 11.0 0.0 2.2 1 0 0 1 1 1 0 AAA domain PLAC9 PF15205.6 OAG38753.1 - 0.15 12.5 0.0 5.4 7.5 0.0 3.0 3 0 0 3 3 3 0 Placenta-specific protein 9 Kinesin PF00225.23 OAG38754.1 - 3.4e-85 285.9 0.1 5e-85 285.4 0.1 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 OAG38754.1 - 1.3e-24 86.8 0.0 2.5e-24 85.9 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding HHH_3 PF12836.7 OAG38754.1 - 0.00016 21.8 0.0 0.00068 19.9 0.0 2.1 1 1 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.6 OAG38754.1 - 0.00024 21.6 0.0 0.00066 20.2 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH PF00633.23 OAG38754.1 - 0.042 13.7 0.0 2 8.4 0.0 2.8 2 0 0 2 2 2 0 Helix-hairpin-helix motif RNA_pol_A_CTD PF03118.15 OAG38754.1 - 0.058 13.2 0.4 0.66 9.8 0.0 2.8 3 1 0 3 3 3 0 Bacterial RNA polymerase, alpha chain C terminal domain PGA2 PF07543.12 OAG38754.1 - 2.1 8.3 9.4 4.3 7.3 9.4 1.5 1 0 0 1 1 1 0 Protein trafficking PGA2 CDC45 PF02724.14 OAG38754.1 - 5.3 5.2 13.8 8.3 4.6 13.8 1.2 1 0 0 1 1 1 0 CDC45-like protein Abhydrolase_1 PF00561.20 OAG38757.1 - 2.1e-13 50.5 0.0 8.1e-12 45.3 0.1 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG38757.1 - 4.3e-10 40.6 3.2 7.2e-10 39.8 3.2 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG38757.1 - 0.00013 21.3 0.1 0.00033 20.0 0.1 1.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Esterase PF00756.20 OAG38757.1 - 0.00098 18.8 0.1 0.0012 18.6 0.1 1.2 1 0 0 1 1 1 1 Putative esterase DLH PF01738.18 OAG38757.1 - 0.11 12.0 0.2 0.33 10.5 0.2 1.8 1 1 1 2 2 2 0 Dienelactone hydrolase family LpxD PF04613.14 OAG38757.1 - 0.15 11.9 0.0 11 5.9 0.0 2.4 2 0 0 2 2 2 0 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD Cnn_1N PF07989.11 OAG38758.1 - 3.7e-24 84.7 8.5 3.7e-24 84.7 8.5 17.4 5 3 11 17 17 17 5 Centrosomin N-terminal motif 1 PACT_coil_coil PF10495.9 OAG38758.1 - 2.7e-19 69.5 0.5 2.7e-19 69.5 0.5 4.6 3 2 1 4 4 4 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein Fez1 PF06818.15 OAG38758.1 - 3e-08 34.3 202.1 0.0014 19.1 14.3 8.1 1 1 6 7 7 7 5 Fez1 GAS PF13851.6 OAG38758.1 - 0.0029 17.0 18.7 0.0029 17.0 18.7 11.6 2 2 9 12 12 12 4 Growth-arrest specific micro-tubule binding TMF_TATA_bd PF12325.8 OAG38758.1 - 0.0075 16.5 14.6 0.0075 16.5 14.6 13.0 2 2 10 12 12 12 2 TATA element modulatory factor 1 TATA binding SlyX PF04102.12 OAG38758.1 - 0.18 12.4 0.1 0.18 12.4 0.1 18.4 4 2 14 20 20 20 0 SlyX SGT1 PF07093.11 OAG38759.1 - 4.1e-95 319.4 9.2 6.2e-86 289.1 0.0 2.1 1 1 1 2 2 2 2 SGT1 protein CDC45 PF02724.14 OAG38759.1 - 1.7 6.9 5.0 2.9 6.1 5.0 1.3 1 0 0 1 1 1 0 CDC45-like protein EHN PF06441.12 OAG38760.1 - 5.5e-33 113.6 0.0 1.8e-32 111.9 0.0 1.9 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 OAG38760.1 - 4e-13 49.6 0.3 7.8e-13 48.7 0.1 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG38760.1 - 0.011 16.4 4.3 0.032 14.9 4.3 1.9 1 1 0 1 1 1 0 Alpha/beta hydrolase family JAB PF01398.21 OAG38761.1 - 2.1e-14 53.5 0.0 3.9e-14 52.6 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease USP8_dimer PF08969.11 OAG38761.1 - 1.6e-11 44.4 0.5 1.6e-11 44.4 0.5 1.6 2 0 0 2 2 2 1 USP8 dimerisation domain Prok-JAB PF14464.6 OAG38761.1 - 3.8e-05 23.4 0.2 0.00012 21.9 0.0 1.9 2 0 0 2 2 2 1 Prokaryotic homologs of the JAB domain WSC PF01822.19 OAG38762.1 - 4e-14 52.5 7.4 8.9e-14 51.4 7.4 1.6 1 0 0 1 1 1 1 WSC domain SKG6 PF08693.10 OAG38762.1 - 8.4e-09 34.7 3.9 2.1e-08 33.4 3.9 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Trp_oprn_chp PF09534.10 OAG38762.1 - 0.017 14.9 0.3 0.05 13.4 0.1 1.9 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Nitrate_red_gam PF02665.14 OAG38762.1 - 0.023 14.2 0.1 0.037 13.6 0.1 1.2 1 0 0 1 1 1 0 Nitrate reductase gamma subunit DUF4448 PF14610.6 OAG38762.1 - 0.025 14.4 0.0 0.035 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Gram_pos_anchor PF00746.21 OAG38762.1 - 0.048 13.6 4.1 0.28 11.2 4.1 2.3 1 1 0 1 1 1 0 LPXTG cell wall anchor motif EphA2_TM PF14575.6 OAG38762.1 - 0.078 13.9 0.1 0.26 12.2 0.0 1.9 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Mid2 PF04478.12 OAG38762.1 - 0.3 10.9 1.8 0.46 10.3 1.3 1.6 1 1 0 1 1 1 0 Mid2 like cell wall stress sensor TBCC PF07986.12 OAG38763.1 - 6.6e-33 113.0 1.2 1.2e-32 112.1 1.2 1.4 1 0 0 1 1 1 1 Tubulin binding cofactor C TBCC_N PF16752.5 OAG38763.1 - 1.1e-07 32.2 0.0 2.1e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Tubulin-specific chaperone C N-terminal domain Peripla_BP_2 PF01497.18 OAG38763.1 - 0.05 13.2 0.0 0.095 12.2 0.0 1.5 1 0 0 1 1 1 0 Periplasmic binding protein RTX PF02382.15 OAG38763.1 - 0.15 11.7 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 N-terminal domain in RTX protein RrnaAD PF00398.20 OAG38764.1 - 6e-06 25.5 0.0 1.7e-05 24.1 0.0 1.8 1 1 0 1 1 1 1 Ribosomal RNA adenine dimethylase DUF1722 PF08349.11 OAG38764.1 - 0.0041 17.4 0.3 0.012 15.9 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1722) Isochorismatase PF00857.20 OAG38765.1 - 3.6e-20 72.9 0.0 1.1e-17 64.7 0.0 2.1 1 1 0 1 1 1 1 Isochorismatase family zf-C2H2_assoc2 PF16624.5 OAG38765.1 - 0.014 16.4 0.5 0.028 15.4 0.5 1.5 1 0 0 1 1 1 0 Unstructured region upstream of a zinc-finger Ank_2 PF12796.7 OAG38767.1 - 2.7e-74 245.8 10.1 4.4e-16 59.2 0.1 8.3 3 1 4 9 9 9 8 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OAG38767.1 - 3.8e-52 168.2 9.0 0.0018 18.6 0.0 16.1 16 0 0 16 16 16 11 Ankyrin repeat Ank_4 PF13637.6 OAG38767.1 - 3.4e-51 171.0 15.1 1e-07 32.3 0.0 11.5 6 3 6 13 13 13 11 Ankyrin repeats (many copies) Ank_5 PF13857.6 OAG38767.1 - 2.2e-47 158.5 15.4 3.5e-07 30.4 0.2 12.3 7 2 5 12 12 12 11 Ankyrin repeats (many copies) Ank PF00023.30 OAG38767.1 - 6.9e-45 149.6 33.0 8.3e-06 26.0 0.0 14.3 15 0 0 15 15 15 10 Ankyrin repeat zf-C3HC4 PF00097.25 OAG38767.1 - 0.00015 21.5 8.9 0.00032 20.5 8.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OAG38767.1 - 0.0015 18.3 7.9 0.0033 17.2 7.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OAG38767.1 - 0.0089 15.8 9.8 0.021 14.7 9.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAG38767.1 - 0.029 14.7 9.1 0.07 13.5 9.1 1.7 1 0 0 1 1 1 0 Ring finger domain Prok-RING_4 PF14447.6 OAG38767.1 - 0.045 13.6 9.5 0.099 12.5 8.6 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 OAG38767.1 - 0.093 12.7 8.6 0.26 11.3 8.6 1.8 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 OAG38767.1 - 0.3 11.2 8.1 0.71 9.9 8.1 1.7 1 0 0 1 1 1 0 RING-type zinc-finger Ank_2 PF12796.7 OAG38768.1 - 2e-34 118.0 2.6 1.2e-07 32.2 0.0 5.8 3 1 1 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OAG38768.1 - 3.6e-29 100.4 4.8 9.8e-06 25.8 0.1 7.2 5 2 2 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG38768.1 - 3.3e-25 85.4 2.4 0.00044 20.5 0.0 9.2 10 0 0 10 10 10 5 Ankyrin repeat Ank_4 PF13637.6 OAG38768.1 - 2.1e-24 85.6 3.0 5.4e-05 23.7 0.2 7.4 6 2 1 7 7 7 5 Ankyrin repeats (many copies) Pkinase_Tyr PF07714.17 OAG38768.1 - 1.5e-21 76.9 0.0 2.9e-21 75.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OAG38768.1 - 4.3e-21 75.5 0.0 6.6e-21 74.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Ank PF00023.30 OAG38768.1 - 1.9e-19 69.1 10.6 0.036 14.5 0.3 8.9 8 0 0 8 8 8 6 Ankyrin repeat Pkinase_fungal PF17667.1 OAG38768.1 - 0.21 10.3 0.0 0.36 9.6 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Peptidase_M20 PF01546.28 OAG38769.1 - 6.5e-30 104.4 0.0 1.2e-29 103.5 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 OAG38769.1 - 4.3e-15 55.6 0.0 8.7e-15 54.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 OAG38769.1 - 0.00069 19.4 0.0 0.0012 18.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 HeLo PF14479.6 OAG38770.1 - 2.7e-28 99.2 0.0 5.5e-28 98.2 0.0 1.4 1 0 0 1 1 1 1 Prion-inhibition and propagation Pkinase PF00069.25 OAG38770.1 - 0.00087 18.7 0.0 0.002 17.6 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain RFamide_26RFa PF11109.8 OAG38771.1 - 0.48 10.9 2.5 0.64 10.5 0.6 2.2 1 1 1 2 2 2 0 Orexigenic neuropeptide Qrfp/P518 SIL1 PF16782.5 OAG38772.1 - 0.024 13.9 0.4 3.9 6.6 0.0 2.2 2 0 0 2 2 2 0 Nucleotide exchange factor SIL1 PCI PF01399.27 OAG38772.1 - 0.03 14.8 0.0 0.078 13.5 0.0 1.6 1 0 0 1 1 1 0 PCI domain Paf67 PF10255.9 OAG38772.1 - 0.035 13.1 1.3 0.055 12.5 0.4 1.7 2 0 0 2 2 2 0 RNA polymerase I-associated factor PAF67 TPR_8 PF13181.6 OAG38772.1 - 0.14 12.4 1.6 0.55 10.6 0.1 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Terminase_6C PF17289.2 OAG38772.1 - 0.16 12.1 0.1 0.29 11.2 0.1 1.4 1 0 0 1 1 1 0 Terminase RNaseH-like domain TPR_2 PF07719.17 OAG38772.1 - 0.33 11.2 1.6 2.3 8.5 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat adh_short PF00106.25 OAG38773.1 - 2.3e-20 72.9 0.0 2.8e-20 72.6 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG38773.1 - 6.8e-15 55.3 0.0 8.2e-15 55.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG38773.1 - 3.4e-09 36.9 0.0 3.9e-09 36.7 0.0 1.0 1 0 0 1 1 1 1 KR domain UL20 PF17582.2 OAG38773.1 - 0.17 11.1 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL20 NifU_N PF01592.16 OAG38774.1 - 9.6e-55 184.2 0.1 1.6e-54 183.5 0.1 1.3 1 0 0 1 1 1 1 NifU-like N terminal domain PC4 PF02229.16 OAG38775.1 - 1.2e-23 82.5 0.8 1.9e-23 81.8 0.8 1.4 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) HBS1_N PF08938.10 OAG38775.1 - 0.062 13.6 1.7 0.28 11.5 0.0 2.3 2 1 0 2 2 2 0 HBS1 N-terminus Hydantoinase_B PF02538.14 OAG38776.1 - 9.5e-224 743.6 0.1 1.3e-223 743.1 0.1 1.2 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 OAG38776.1 - 3.2e-105 351.6 0.2 7.5e-105 350.4 0.2 1.7 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 OAG38776.1 - 7e-60 201.8 2.0 1.8e-58 197.2 0.0 2.9 3 0 0 3 3 3 1 Hydantoinase/oxoprolinase N-terminal region Pkinase PF00069.25 OAG38777.1 - 2.5e-69 233.6 0.0 3.3e-69 233.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG38777.1 - 2.7e-42 144.9 0.0 3.5e-42 144.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAG38777.1 - 1.1e-06 28.3 0.0 5.1e-06 26.0 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 OAG38777.1 - 0.00029 20.3 0.1 0.00061 19.2 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OAG38777.1 - 0.0033 16.4 0.0 0.0052 15.8 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 OAG38777.1 - 0.023 14.3 0.2 0.28 10.8 0.0 2.4 2 1 0 3 3 3 0 RIO1 family FTA2 PF13095.6 OAG38777.1 - 0.063 12.9 0.1 0.27 10.8 0.0 1.9 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 OAG38777.1 - 0.089 12.7 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family TIP41 PF04176.13 OAG38778.1 - 8.1e-69 230.5 0.0 9.9e-69 230.2 0.0 1.1 1 0 0 1 1 1 1 TIP41-like family SKG6 PF08693.10 OAG38779.1 - 1.6e-05 24.2 0.0 4.5e-05 22.8 0.0 1.9 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Rax2 PF12768.7 OAG38779.1 - 0.0021 17.6 0.5 0.0021 17.6 0.5 1.6 2 0 0 2 2 2 1 Cortical protein marker for cell polarity VSP PF03302.13 OAG38779.1 - 0.69 8.7 7.2 0.023 13.5 1.1 1.5 2 0 0 2 2 2 0 Giardia variant-specific surface protein Plasmodium_Vir PF05795.11 OAG38779.1 - 0.9 8.9 2.9 0.46 9.8 0.5 1.6 1 1 1 2 2 2 0 Plasmodium vivax Vir protein Fungal_trans_2 PF11951.8 OAG38780.1 - 6.2e-15 54.9 0.0 1.2e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2 PF09337.10 OAG38780.1 - 6.9e-15 55.0 3.0 1.7e-14 53.7 3.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger Integrase_H2C2 PF17921.1 OAG38780.1 - 5.1e-11 42.5 0.5 1.3e-10 41.2 0.5 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain Acetyltransf_1 PF00583.25 OAG38780.1 - 0.00011 22.4 0.0 0.00024 21.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 OAG38780.1 - 0.0044 17.7 0.0 0.0096 16.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OAG38780.1 - 0.022 15.2 0.0 0.05 14.0 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PA14 PF07691.12 OAG38780.1 - 0.069 13.0 0.1 0.14 12.0 0.1 1.4 1 0 0 1 1 1 0 PA14 domain Acetyltransf_4 PF13420.7 OAG38780.1 - 0.12 12.5 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Amidase PF01425.21 OAG38781.1 - 1.1e-94 318.0 0.0 1.6e-94 317.4 0.0 1.2 1 0 0 1 1 1 1 Amidase DAO PF01266.24 OAG38782.1 - 5.5e-35 121.6 1.4 6.6e-35 121.3 1.4 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 OAG38782.1 - 0.00015 21.1 0.0 0.00029 20.1 0.0 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 OAG38782.1 - 0.00036 20.7 0.1 0.001 19.2 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 OAG38782.1 - 0.00089 18.4 0.1 0.0014 17.8 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 OAG38782.1 - 0.00095 18.5 0.1 0.0014 18.0 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAG38782.1 - 0.002 18.2 0.2 0.019 15.0 0.1 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding Mqo PF06039.15 OAG38782.1 - 0.0028 16.3 0.1 0.0038 15.8 0.1 1.1 1 0 0 1 1 1 1 Malate:quinone oxidoreductase (Mqo) MdcE PF06833.11 OAG38782.1 - 0.0031 17.0 0.0 0.0046 16.5 0.0 1.2 1 0 0 1 1 1 1 Malonate decarboxylase gamma subunit (MdcE) Pyr_redox_3 PF13738.6 OAG38782.1 - 0.01 15.1 0.0 1.6 7.9 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAG38782.1 - 0.023 13.8 0.2 0.046 12.8 0.2 1.5 1 0 0 1 1 1 0 FAD binding domain K_oxygenase PF13434.6 OAG38782.1 - 0.029 13.5 0.0 0.043 13.0 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) MCRA PF06100.11 OAG38782.1 - 0.044 12.6 0.3 0.063 12.1 0.3 1.1 1 0 0 1 1 1 0 MCRA family MFS_1 PF07690.16 OAG38783.1 - 1.7e-26 93.0 29.7 1e-25 90.4 23.0 2.9 1 1 2 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG38783.1 - 1.4e-06 27.5 9.3 1.4e-06 27.5 9.3 3.3 3 0 0 3 3 3 2 Sugar (and other) transporter Trp_oprn_chp PF09534.10 OAG38783.1 - 2.2 8.0 6.4 11 5.8 3.7 2.4 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) PMP1_2 PF08114.11 OAG38783.1 - 7.5 6.4 9.2 0.54 10.0 0.6 3.0 3 0 0 3 3 3 0 ATPase proteolipid family Kelch_1 PF01344.25 OAG38784.1 - 0.0014 18.1 0.7 1.6 8.4 0.0 3.7 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.15 OAG38784.1 - 0.0048 16.8 0.2 0.077 13.0 0.0 3.0 4 0 0 4 4 4 1 Kelch motif Kelch_6 PF13964.6 OAG38784.1 - 0.0082 16.4 0.6 22 5.5 0.0 3.6 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.6 OAG38784.1 - 0.043 13.8 2.2 6.3 6.9 0.3 3.1 3 0 0 3 3 3 0 Galactose oxidase, central domain Kelch_5 PF13854.6 OAG38784.1 - 4.7 7.3 0.0 4.7 7.3 0.0 3.6 5 1 1 6 6 6 0 Kelch motif Kelch_5 PF13854.6 OAG38785.1 - 6.5e-11 42.0 0.6 3.4e-09 36.5 0.4 2.6 2 0 0 2 2 2 1 Kelch motif Herpes_gE PF02480.16 OAG38785.1 - 0.059 12.1 0.1 0.087 11.6 0.1 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Kelch_4 PF13418.6 OAG38785.1 - 4.7 7.3 10.6 0.15 12.1 1.2 3.0 3 0 0 3 3 3 0 Galactose oxidase, central domain Cpn60_TCP1 PF00118.24 OAG38786.1 - 1.3e-154 515.5 4.0 1.5e-154 515.3 4.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Rep_fac_C PF08542.11 OAG38786.1 - 0.034 14.6 0.0 2.5 8.5 0.0 2.9 2 0 0 2 2 2 0 Replication factor C C-terminal domain Peptidase_C14 PF00656.22 OAG38787.1 - 4.6e-61 206.9 0.0 6e-61 206.5 0.0 1.1 1 0 0 1 1 1 1 Caspase domain F-box-like PF12937.7 OAG38788.1 - 0.00082 19.2 1.4 0.002 18.0 1.4 1.6 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 OAG38788.1 - 0.0099 16.3 9.6 1.5 9.4 0.0 6.0 6 1 1 7 7 7 1 Leucine Rich repeats (2 copies) NUFIP1 PF10453.9 OAG38788.1 - 0.18 11.7 0.5 0.35 10.7 0.5 1.4 1 0 0 1 1 1 0 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) LRR_1 PF00560.33 OAG38788.1 - 0.19 12.4 0.3 15 6.6 0.1 3.9 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_6 PF13516.6 OAG38788.1 - 1.1 9.5 9.1 0.53 10.5 0.1 3.9 5 0 0 5 5 5 0 Leucine Rich repeat Folliculin PF11704.8 OAG38789.1 - 7.8e-48 162.8 0.0 1.6e-47 161.8 0.0 1.6 1 0 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport CLP1_P PF16575.5 OAG38790.1 - 1.7e-10 41.0 0.0 3.2e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop RNA_polI_A34 PF08208.11 OAG38791.1 - 3.7e-28 99.0 5.6 3.7e-28 99.0 5.6 2.9 2 1 0 2 2 2 1 DNA-directed RNA polymerase I subunit RPA34.5 SRP-alpha_N PF04086.13 OAG38791.1 - 5.1 6.9 31.0 3.1 7.6 7.0 2.1 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal DUF780 PF05611.11 OAG38791.1 - 6 7.7 7.4 2.7 8.8 2.5 2.4 2 0 0 2 2 2 0 Caenorhabditis elegans protein of unknown function (DUF780) NOA36 PF06524.12 OAG38791.1 - 8.3 5.6 13.1 17 4.6 13.1 1.4 1 0 0 1 1 1 0 NOA36 protein Macoilin PF09726.9 OAG38791.1 - 9.6 4.6 18.1 3.3 6.1 0.3 2.2 2 0 0 2 2 2 0 Macoilin family SHMT PF00464.19 OAG38792.1 - 5.3e-209 693.7 0.0 6.2e-209 693.5 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.21 OAG38792.1 - 4.9e-07 29.3 0.0 1.1e-06 28.2 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II Baculo_DNA_bind PF04786.12 OAG38792.1 - 0.053 12.9 0.0 0.094 12.1 0.0 1.3 1 0 0 1 1 1 0 ssDNA binding protein Cys_Met_Meta_PP PF01053.20 OAG38792.1 - 0.056 12.0 0.0 0.092 11.3 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 OAG38792.1 - 0.15 11.4 0.0 0.31 10.3 0.0 1.5 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Med9 PF07544.13 OAG38793.1 - 3.5e-13 49.4 0.0 1.1e-12 47.8 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 SlyX PF04102.12 OAG38793.1 - 0.0024 18.4 0.4 0.0024 18.4 0.4 2.9 2 2 0 2 2 2 1 SlyX SMN PF06003.12 OAG38793.1 - 0.0076 15.5 0.3 0.0076 15.5 0.3 1.5 2 0 0 2 2 2 1 Survival motor neuron protein (SMN) HrpB7 PF09486.10 OAG38793.1 - 0.0076 16.7 1.4 0.0076 16.7 1.4 1.6 2 0 0 2 2 2 1 Bacterial type III secretion protein (HrpB7) BST2 PF16716.5 OAG38793.1 - 0.016 15.8 6.8 0.15 12.6 3.0 2.8 2 1 1 3 3 3 0 Bone marrow stromal antigen 2 SOG2 PF10428.9 OAG38793.1 - 0.06 12.5 6.8 0.064 12.4 6.8 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Spc42p PF11544.8 OAG38793.1 - 0.15 12.1 0.0 0.15 12.1 0.0 2.0 3 0 0 3 3 3 0 Spindle pole body component Spc42p Med21 PF11221.8 OAG38793.1 - 0.18 12.0 0.1 0.18 12.0 0.1 2.7 2 1 0 2 2 2 0 Subunit 21 of Mediator complex EthD PF07110.11 OAG38794.1 - 3.6e-18 66.5 0.1 1.1e-17 65.0 0.1 1.6 1 1 0 1 1 1 1 EthD domain MmlI PF09448.10 OAG38794.1 - 0.00089 19.7 0.0 0.0018 18.7 0.0 1.5 1 1 0 1 1 1 1 Methylmuconolactone methyl-isomerase BTHB PF18410.1 OAG38794.1 - 0.059 13.2 0.1 0.097 12.5 0.1 1.3 1 0 0 1 1 1 0 Basic tilted helix bundle domain LANC_like PF05147.13 OAG38795.1 - 1.2e-29 103.0 0.0 5.1e-29 100.9 0.0 1.8 1 1 0 1 1 1 1 Lanthionine synthetase C-like protein Lipocalin_5 PF13924.6 OAG38796.1 - 6.9e-26 90.7 0.0 7.9e-26 90.5 0.0 1.0 1 0 0 1 1 1 1 Lipocalin-like domain adh_short PF00106.25 OAG38797.1 - 3e-19 69.3 0.0 7.4e-19 68.0 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG38797.1 - 1.5e-18 67.2 0.0 2.2e-18 66.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase HET PF06985.11 OAG38798.1 - 4.1e-26 92.1 0.6 7.7e-26 91.2 0.6 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) NUDIX PF00293.28 OAG38799.1 - 3.5e-10 40.0 0.1 6.9e-10 39.1 0.1 1.5 1 0 0 1 1 1 1 NUDIX domain ATP_transf PF09830.9 OAG38800.1 - 1.5e-19 69.9 1.1 3e-19 68.9 1.1 1.5 1 0 0 1 1 1 1 ATP adenylyltransferase SIR2_2 PF13289.6 OAG38801.1 - 4.4e-05 23.6 0.0 0.0003 20.9 0.0 2.5 2 1 0 2 2 2 1 SIR2-like domain SHNi-TPR PF10516.9 OAG38801.1 - 0.18 11.3 0.6 0.38 10.2 0.6 1.6 1 0 0 1 1 1 0 SHNi-TPR RNA12 PF10443.9 OAG38801.1 - 0.21 10.3 0.0 0.43 9.3 0.0 1.4 1 0 0 1 1 1 0 RNA12 protein Zn_clus PF00172.18 OAG38802.1 - 8.9e-07 28.9 7.3 1.5e-06 28.2 7.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SF3b1 PF08920.10 OAG38803.1 - 8.3e-31 106.9 10.3 2.5e-29 102.2 10.3 3.0 1 1 0 1 1 1 1 Splicing factor 3B subunit 1 HEAT_EZ PF13513.6 OAG38803.1 - 1.9e-12 47.4 2.0 0.012 16.1 0.0 7.5 7 1 1 8 8 8 2 HEAT-like repeat HEAT_2 PF13646.6 OAG38803.1 - 1.2e-11 44.8 9.4 0.21 12.0 0.1 8.7 5 2 4 10 10 10 4 HEAT repeats HEAT PF02985.22 OAG38803.1 - 4.2e-09 35.9 9.2 0.087 13.1 0.3 8.8 8 0 0 8 8 8 2 HEAT repeat Cnd1 PF12717.7 OAG38803.1 - 2.2e-07 31.1 3.0 0.18 11.9 0.0 6.1 5 2 2 7 7 7 1 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 OAG38803.1 - 3.3e-06 27.6 0.2 1.8 9.2 0.0 5.5 5 0 0 5 5 5 1 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 OAG38803.1 - 3.4e-06 25.9 1.2 0.0033 16.0 0.1 3.3 3 1 0 3 3 3 2 Adaptin N terminal region NUC173 PF08161.12 OAG38803.1 - 0.00013 21.7 0.3 1.1 8.9 0.0 4.3 4 1 1 5 5 5 2 NUC173 domain DUF3385 PF11865.8 OAG38803.1 - 0.00015 21.7 1.5 0.023 14.6 0.0 4.7 5 1 1 6 6 6 1 Domain of unknown function (DUF3385) UNC45-central PF11701.8 OAG38803.1 - 0.00034 20.6 0.0 0.0012 18.8 0.0 1.9 2 0 0 2 2 2 1 Myosin-binding striated muscle assembly central CLASP_N PF12348.8 OAG38803.1 - 0.0022 17.6 0.5 0.9 9.1 0.0 3.6 4 0 0 4 4 4 1 CLASP N terminal DRIM PF07539.12 OAG38803.1 - 0.036 12.4 0.4 6.4 4.9 0.0 3.8 2 1 2 4 4 4 0 Down-regulated in metastasis MMS19_C PF12460.8 OAG38803.1 - 0.085 11.9 0.0 7.3 5.6 0.0 3.3 3 1 1 4 4 4 0 RNAPII transcription regulator C-terminal RasGAP PF00616.19 OAG38804.1 - 1.5e-31 109.8 0.0 3.4e-20 72.6 0.0 2.7 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase C2 PF00168.30 OAG38804.1 - 0.11 12.7 0.5 0.55 10.6 0.0 2.4 2 1 0 2 2 2 0 C2 domain PPR_2 PF13041.6 OAG38805.1 - 0.00029 20.9 0.0 0.00058 20.0 0.0 1.4 1 0 0 1 1 1 1 PPR repeat family PCRF PF03462.18 OAG38806.1 - 1.1e-50 172.3 0.0 2.6e-50 171.0 0.0 1.7 1 0 0 1 1 1 1 PCRF domain RF-1 PF00472.20 OAG38806.1 - 1.7e-35 121.4 1.8 4.7e-35 120.0 1.8 1.8 1 0 0 1 1 1 1 RF-1 domain zf-CCCH_4 PF18044.1 OAG38806.1 - 1e-06 28.4 2.3 1.7e-06 27.7 2.3 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 OAG38806.1 - 2.9e-05 23.8 1.6 4.9e-05 23.1 1.6 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 OAG38806.1 - 0.00047 20.8 0.3 0.0011 19.6 0.3 1.6 1 0 0 1 1 1 1 Torus domain zf_CCCH_4 PF18345.1 OAG38806.1 - 0.00064 19.7 6.7 0.0012 18.9 6.7 1.4 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_2 PF14608.6 OAG38806.1 - 0.28 11.7 3.1 0.51 10.9 3.1 1.4 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger eIF3_N PF09440.10 OAG38807.1 - 6.8e-43 146.3 7.5 1.1e-42 145.7 6.2 2.0 2 0 0 2 2 2 1 eIF3 subunit 6 N terminal domain PCI PF01399.27 OAG38807.1 - 2.6e-13 50.4 0.0 1.1e-12 48.4 0.0 2.1 1 0 0 1 1 1 1 PCI domain DUF148 PF02520.17 OAG38807.1 - 0.4 10.8 5.1 1.2 9.3 0.7 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF148 Img2 PF05046.14 OAG38808.1 - 1.1e-23 83.3 0.1 1.4e-23 83.0 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) ARID PF01388.21 OAG38809.1 - 3.1e-20 72.6 0.0 7.4e-20 71.4 0.0 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain AAA PF00004.29 OAG38810.1 - 4.4e-45 153.3 0.7 1.4e-44 151.7 0.0 2.1 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 OAG38810.1 - 3.2e-10 39.8 0.1 2.1e-09 37.2 0.0 2.2 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 OAG38810.1 - 7.8e-09 35.6 0.1 2.8e-08 33.9 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 OAG38810.1 - 6.3e-08 32.9 0.0 1.3e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 OAG38810.1 - 1.9e-07 31.6 0.5 3.7e-05 24.2 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain DUF815 PF05673.13 OAG38810.1 - 4.3e-06 26.1 0.0 8e-06 25.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 OAG38810.1 - 4.1e-05 23.9 1.3 0.0081 16.4 0.1 2.6 1 1 0 2 2 2 1 AAA domain AAA_7 PF12775.7 OAG38810.1 - 7e-05 22.4 0.0 0.0078 15.7 0.1 2.9 2 1 0 2 2 2 1 P-loop containing dynein motor region RuvB_N PF05496.12 OAG38810.1 - 0.00039 20.2 0.0 0.0011 18.7 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_lid_3 PF17862.1 OAG38810.1 - 0.00044 20.0 0.1 0.00099 18.9 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_18 PF13238.6 OAG38810.1 - 0.00084 19.9 0.0 0.0026 18.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 OAG38810.1 - 0.00095 19.4 0.0 0.002 18.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 OAG38810.1 - 0.0012 19.3 0.0 0.0031 17.9 0.0 1.7 1 0 0 1 1 1 1 RNA helicase TIP49 PF06068.13 OAG38810.1 - 0.0012 18.1 0.0 0.0024 17.1 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain TsaE PF02367.17 OAG38810.1 - 0.0015 18.5 0.0 0.024 14.6 0.0 2.2 1 1 1 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 OAG38810.1 - 0.0023 17.9 0.0 0.0087 16.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 OAG38810.1 - 0.0026 17.7 0.0 0.012 15.5 0.0 2.0 2 0 0 2 2 2 1 NTPase AAA_30 PF13604.6 OAG38810.1 - 0.0057 16.4 0.1 0.014 15.2 0.1 1.7 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 OAG38810.1 - 0.0067 16.4 0.5 0.11 12.4 0.0 2.8 4 0 0 4 4 2 1 NACHT domain AAA_3 PF07726.11 OAG38810.1 - 0.0068 16.3 0.0 0.02 14.8 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 OAG38810.1 - 0.0083 15.5 0.0 0.019 14.3 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 OAG38810.1 - 0.0095 16.1 0.0 0.02 15.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain TniB PF05621.11 OAG38810.1 - 0.011 15.2 0.0 0.55 9.6 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein IstB_IS21 PF01695.17 OAG38810.1 - 0.014 15.2 0.1 0.043 13.5 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_24 PF13479.6 OAG38810.1 - 0.023 14.4 0.2 0.051 13.3 0.2 1.7 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 OAG38810.1 - 0.044 13.7 1.1 0.23 11.4 0.1 2.5 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea ATPase PF06745.13 OAG38810.1 - 0.05 12.9 1.1 0.56 9.5 0.0 2.4 3 0 0 3 3 2 0 KaiC AAA_11 PF13086.6 OAG38810.1 - 0.057 13.2 0.1 0.14 11.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain Bac_DnaA PF00308.18 OAG38810.1 - 0.071 12.9 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein Sigma54_activat PF00158.26 OAG38810.1 - 0.084 12.6 0.2 1.4 8.6 0.0 2.5 2 1 0 2 2 2 0 Sigma-54 interaction domain AFG1_ATPase PF03969.16 OAG38810.1 - 0.089 11.7 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 AFG1-like ATPase Viral_Hsp90 PF03225.14 OAG38810.1 - 0.12 10.8 0.0 0.19 10.2 0.0 1.2 1 0 0 1 1 1 0 Viral heat shock protein Hsp90 homologue AAA_19 PF13245.6 OAG38810.1 - 0.13 12.6 0.1 0.41 11.0 0.1 1.8 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 OAG38810.1 - 0.14 11.7 1.8 0.23 11.0 0.2 2.1 2 1 1 3 3 3 0 AAA domain AAA_29 PF13555.6 OAG38810.1 - 0.18 11.6 0.0 0.35 10.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Parvo_NS1 PF01057.17 OAG38810.1 - 0.21 10.7 0.0 0.39 9.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Aft1_HRA PF11786.8 OAG38811.1 - 1.9e-25 89.0 7.2 1.9e-25 89.0 7.2 3.2 2 1 1 3 3 3 1 Aft1 HRA domain Aft1_OSA PF11785.8 OAG38811.1 - 4.9e-16 58.9 10.6 4.9e-16 58.9 10.6 3.3 3 1 1 4 4 4 1 Aft1 osmotic stress response (OSM) domain Aft1_HRR PF11787.8 OAG38811.1 - 2.5e-15 57.4 7.5 2.5e-15 57.4 7.5 4.8 3 3 0 3 3 3 1 Aft1 HRR domain bZIP_1 PF00170.21 OAG38811.1 - 4.6e-11 42.7 6.3 7.6e-11 42.0 6.3 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 OAG38811.1 - 5.4e-06 26.4 6.0 1.2e-05 25.3 6.0 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 OAG38811.1 - 0.0021 18.5 4.2 0.0062 17.0 4.2 1.8 1 0 0 1 1 1 1 bZIP Maf transcription factor CDO_I PF05995.12 OAG38811.1 - 0.053 12.8 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 Cysteine dioxygenase type I DivIC PF04977.15 OAG38811.1 - 0.092 12.5 1.3 0.19 11.5 1.3 1.4 1 0 0 1 1 1 0 Septum formation initiator Pyridoxal_deC PF00282.19 OAG38812.1 - 8.1e-70 235.4 0.0 1.5e-67 227.9 0.0 2.8 2 1 0 2 2 2 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 OAG38812.1 - 7e-05 22.2 0.0 0.00012 21.5 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 OAG38812.1 - 0.0006 18.9 0.0 0.0011 18.0 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V PUF PF00806.19 OAG38813.1 - 5.9e-12 44.6 0.0 0.088 12.5 0.0 7.6 9 0 0 9 9 9 4 Pumilio-family RNA binding repeat Prefoldin_2 PF01920.20 OAG38814.1 - 1.8e-19 69.7 11.5 2.2e-19 69.4 11.5 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_3 PF13758.6 OAG38814.1 - 0.0021 18.1 2.7 0.0025 17.8 2.3 1.3 1 1 0 1 1 1 1 Prefoldin subunit Fib_alpha PF08702.10 OAG38814.1 - 0.031 14.5 10.7 0.11 12.7 10.7 1.7 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family EAP30 PF04157.16 OAG38814.1 - 0.1 11.9 4.2 0.048 12.9 2.0 1.4 1 1 0 1 1 1 0 EAP30/Vps36 family NPV_P10 PF05531.12 OAG38814.1 - 0.12 12.9 11.6 0.31 11.5 4.0 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.12 OAG38814.1 - 0.32 11.1 10.6 0.84 9.7 1.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DHR10 PF18595.1 OAG38814.1 - 0.34 11.0 18.2 0.073 13.1 5.8 2.2 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain DUF4510 PF14971.6 OAG38814.1 - 0.39 11.1 6.8 9.9 6.5 6.8 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4510) DUF4201 PF13870.6 OAG38814.1 - 0.4 10.4 12.5 0.65 9.7 3.2 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4201) YabA PF06156.13 OAG38814.1 - 0.52 11.0 9.7 4.1 8.1 1.2 2.1 2 0 0 2 2 2 0 Initiation control protein YabA Spc7 PF08317.11 OAG38814.1 - 1.1 8.1 16.1 4 6.2 16.1 1.7 1 1 0 1 1 1 0 Spc7 kinetochore protein PEP-utilisers_N PF05524.13 OAG38814.1 - 1.2 9.3 11.4 2.9 8.1 3.6 2.1 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal DUF4407 PF14362.6 OAG38814.1 - 1.2 8.4 10.7 1.5 8.1 10.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FlxA PF14282.6 OAG38814.1 - 1.3 9.0 18.7 0.12 12.4 3.3 2.2 2 0 0 2 2 2 0 FlxA-like protein Prefoldin PF02996.17 OAG38814.1 - 1.4 8.9 12.7 1 9.3 1.7 2.2 2 0 0 2 2 2 0 Prefoldin subunit Tropomyosin_1 PF12718.7 OAG38814.1 - 2.2 8.4 15.5 4.7 7.4 2.2 2.1 2 0 0 2 2 2 0 Tropomyosin like Rx_N PF18052.1 OAG38814.1 - 4.3 7.7 10.2 12 6.3 3.4 2.1 2 0 0 2 2 2 0 Rx N-terminal domain DUF2203 PF09969.9 OAG38814.1 - 6.6 7.5 7.7 16 6.2 7.7 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) BRE1 PF08647.11 OAG38814.1 - 7.5 6.7 16.6 1.4 9.0 2.8 2.4 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase RF-1 PF00472.20 OAG38814.1 - 8.3 6.4 10.8 1.3 9.0 2.6 2.1 2 0 0 2 2 2 0 RF-1 domain APG6_N PF17675.1 OAG38814.1 - 9.5 6.8 19.1 7.1 7.2 4.5 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region AAA PF00004.29 OAG38815.1 - 6.1e-42 143.2 0.0 1e-41 142.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 OAG38815.1 - 2.3e-31 107.6 0.2 8.5e-31 105.8 0.1 2.1 3 0 0 3 3 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 OAG38815.1 - 1.1e-21 76.6 3.8 2.6e-21 75.4 3.8 1.7 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 OAG38815.1 - 5.4e-06 26.1 0.0 5.7e-05 22.8 0.0 2.4 2 0 0 2 2 2 1 AAA+ lid domain RuvB_N PF05496.12 OAG38815.1 - 1.1e-05 25.3 0.0 2.1e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 OAG38815.1 - 1.3e-05 25.6 0.0 0.00016 22.1 0.0 2.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 OAG38815.1 - 2.5e-05 24.3 0.0 0.00012 22.0 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 OAG38815.1 - 3.2e-05 23.3 0.0 5.4e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain RNA_helicase PF00910.22 OAG38815.1 - 6.3e-05 23.3 0.0 0.011 16.1 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_22 PF13401.6 OAG38815.1 - 8.4e-05 22.9 0.1 0.019 15.2 0.0 2.8 2 1 1 3 3 2 1 AAA domain IstB_IS21 PF01695.17 OAG38815.1 - 8.4e-05 22.4 0.0 0.00018 21.3 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 OAG38815.1 - 0.00025 21.6 0.0 0.0022 18.5 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.6 OAG38815.1 - 0.00036 20.6 0.0 0.0007 19.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 OAG38815.1 - 0.00048 19.4 0.0 0.0014 17.9 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF815) AAA_2 PF07724.14 OAG38815.1 - 0.00062 19.9 0.0 0.0081 16.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_24 PF13479.6 OAG38815.1 - 0.00096 18.9 0.0 0.011 15.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 OAG38815.1 - 0.0016 18.6 0.0 0.004 17.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 OAG38815.1 - 0.0031 17.9 0.1 0.037 14.4 0.0 2.7 3 0 0 3 3 2 1 AAA domain AAA_25 PF13481.6 OAG38815.1 - 0.0056 16.3 0.6 0.49 9.9 0.1 3.1 2 2 1 3 3 3 1 AAA domain AAA_7 PF12775.7 OAG38815.1 - 0.014 14.9 0.1 0.075 12.5 0.0 2.2 2 1 0 2 2 2 0 P-loop containing dynein motor region ATPase PF06745.13 OAG38815.1 - 0.018 14.4 0.1 7.1 5.9 0.0 3.1 2 1 1 3 3 3 0 KaiC Torsin PF06309.11 OAG38815.1 - 0.018 15.1 0.0 0.085 13.0 0.0 2.0 2 0 0 2 2 2 0 Torsin Mg_chelatase PF01078.21 OAG38815.1 - 0.026 13.9 0.0 0.081 12.3 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Parvo_NS1 PF01057.17 OAG38815.1 - 0.044 12.9 0.0 0.096 11.8 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ATPase_2 PF01637.18 OAG38815.1 - 0.063 13.2 0.1 1.4 8.8 0.0 2.4 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea NACHT PF05729.12 OAG38815.1 - 0.081 12.8 0.0 0.67 9.8 0.0 2.2 1 1 1 2 2 2 0 NACHT domain PhoH PF02562.16 OAG38815.1 - 0.084 12.3 0.1 0.16 11.4 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein CPT PF07931.12 OAG38815.1 - 0.12 12.2 0.0 0.52 10.1 0.0 1.9 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Use1 PF09753.9 OAG38815.1 - 0.13 12.0 0.2 0.23 11.1 0.2 1.4 1 0 0 1 1 1 0 Membrane fusion protein Use1 AFG1_ATPase PF03969.16 OAG38815.1 - 0.16 10.8 0.0 0.4 9.5 0.0 1.6 1 0 0 1 1 1 0 AFG1-like ATPase Cytidylate_kin PF02224.18 OAG38815.1 - 0.35 10.6 2.4 0.51 10.0 0.0 2.4 3 1 1 4 4 3 0 Cytidylate kinase Zeta_toxin PF06414.12 OAG38815.1 - 1.3 8.2 4.1 1.5 8.0 0.1 2.9 3 1 1 4 4 4 0 Zeta toxin XFP_N PF09364.10 OAG38816.1 - 4.5e-170 565.3 0.0 6e-170 564.9 0.0 1.2 1 0 0 1 1 1 1 XFP N-terminal domain XFP_C PF09363.10 OAG38816.1 - 6.7e-85 283.6 0.0 9.6e-85 283.1 0.0 1.2 1 0 0 1 1 1 1 XFP C-terminal domain XFP PF03894.15 OAG38816.1 - 3.4e-81 271.2 0.0 5.1e-81 270.6 0.0 1.3 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase COesterase PF00135.28 OAG38818.1 - 2.3e-84 284.1 0.0 3.1e-84 283.7 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAG38818.1 - 1.7e-06 28.0 0.8 2.5e-05 24.2 0.8 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold ELYS PF13934.6 OAG38819.1 - 1.1e-54 185.7 0.8 1.3e-54 185.5 0.8 1.1 1 0 0 1 1 1 1 Nuclear pore complex assembly Epimerase PF01370.21 OAG38820.1 - 0.00058 19.4 0.0 0.00075 19.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 OAG38820.1 - 0.00076 19.4 0.0 0.0011 18.9 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 OAG38820.1 - 0.074 12.2 0.0 2.6 7.2 0.0 2.3 2 0 0 2 2 2 0 Male sterility protein TRP PF06011.12 OAG38822.1 - 2.5e-164 547.1 33.6 3e-164 546.8 33.6 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 OAG38822.1 - 3.9e-41 140.7 1.5 6.5e-41 139.9 1.5 1.4 1 0 0 1 1 1 1 ML-like domain DUF4106 PF13388.6 OAG38822.1 - 0.51 9.5 5.5 0.94 8.6 5.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) zf-PHD-like PF15446.6 OAG38823.1 - 9.4e-67 223.8 13.7 9.4e-67 223.8 13.7 1.9 2 0 0 2 2 1 1 PHD/FYVE-zinc-finger like domain SNF2_N PF00176.23 OAG38823.1 - 1e-51 175.7 0.1 1.9e-51 174.9 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-CCCH_6 PF18585.1 OAG38823.1 - 5.4e-27 93.4 1.3 1.9e-26 91.7 1.3 2.1 1 0 0 1 1 1 1 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 Helicase_C PF00271.31 OAG38823.1 - 1e-18 67.7 0.0 3.1e-18 66.1 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 OAG38823.1 - 5e-07 29.2 0.5 1.5e-06 27.6 0.5 1.7 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.15 OAG38823.1 - 1.9e-06 28.0 0.0 4.3e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PHD PF00628.29 OAG38823.1 - 0.00017 21.4 5.4 0.00017 21.4 5.4 3.7 3 2 0 3 3 2 1 PHD-finger Chromo PF00385.24 OAG38823.1 - 0.0002 21.2 4.9 0.029 14.3 0.3 3.4 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain DUF1087 PF06465.13 OAG38823.1 - 0.00075 19.5 0.1 0.0027 17.7 0.1 2.0 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1087) SnAC PF14619.6 OAG38823.1 - 0.0037 17.9 0.1 0.0037 17.9 0.1 3.8 4 1 0 4 4 3 1 Snf2-ATP coupling, chromatin remodelling complex DUF4537 PF15057.6 OAG38823.1 - 0.066 13.2 0.0 13 5.9 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4537) DEAD PF00270.29 OAG38823.1 - 0.071 12.9 0.0 0.23 11.2 0.0 1.9 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA_22 PF13401.6 OAG38823.1 - 0.084 13.1 0.0 0.45 10.8 0.0 2.3 2 0 0 2 2 1 0 AAA domain SpoU_methylase PF00588.19 OAG38824.1 - 1.4e-23 83.6 0.0 3.2e-23 82.5 0.0 1.6 2 0 0 2 2 2 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 OAG38824.1 - 0.0021 18.3 0.0 0.045 14.0 0.0 2.5 1 1 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding Glyco_hydro_36 PF17167.4 OAG38824.1 - 0.12 11.0 0.0 0.16 10.6 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase 36 superfamily, catalytic domain Phage-Gp8 PF09215.10 OAG38825.1 - 0.11 11.5 0.0 0.16 11.0 0.0 1.1 1 0 0 1 1 1 0 Bacteriophage T4, Gp8 Ammonium_transp PF00909.21 OAG38826.1 - 1.4e-65 221.6 23.0 3.4e-35 121.5 9.2 2.5 2 1 0 2 2 2 2 Ammonium Transporter Family Patatin PF01734.22 OAG38827.1 - 6.3e-22 78.8 0.7 6.3e-22 78.8 0.7 2.6 3 0 0 3 3 3 1 Patatin-like phospholipase RsgA_GTPase PF03193.16 OAG38827.1 - 0.001 19.0 0.3 0.0024 17.8 0.1 1.7 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 OAG38827.1 - 0.0027 18.1 1.4 0.1 13.0 0.4 3.4 3 1 0 3 3 3 1 AAA ATPase domain zf-C3HC4 PF00097.25 OAG38827.1 - 0.0084 16.0 5.0 0.027 14.4 5.0 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) AAA_29 PF13555.6 OAG38827.1 - 0.011 15.4 0.1 0.038 13.7 0.1 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 OAG38827.1 - 0.011 15.8 0.5 0.033 14.3 0.5 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.27 OAG38827.1 - 0.018 15.5 0.0 0.045 14.3 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_33 PF13671.6 OAG38827.1 - 0.035 14.3 0.3 0.25 11.5 0.0 2.7 2 1 1 3 3 3 0 AAA domain AAA_21 PF13304.6 OAG38827.1 - 0.038 13.8 0.0 0.11 12.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OAG38827.1 - 0.12 11.8 0.1 0.27 10.7 0.1 1.5 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain zf-C3HC4_4 PF15227.6 OAG38827.1 - 0.27 11.4 5.8 1.1 9.4 5.8 2.1 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Fig1 PF12351.8 OAG38828.1 - 1.3e-58 198.1 6.4 1.3e-58 198.1 6.4 2.0 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.12 OAG38828.1 - 4.4e-07 29.7 8.8 6.5e-07 29.2 8.8 1.2 1 0 0 1 1 1 1 SUR7/PalI family DUF898 PF05987.13 OAG38828.1 - 0.13 11.2 13.5 0.35 9.9 13.5 1.7 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF898) XPG_I PF00867.18 OAG38829.1 - 8.5e-22 77.3 0.0 1.9e-21 76.2 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 OAG38829.1 - 7.5e-20 71.3 0.0 1.8e-19 70.1 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.7 OAG38829.1 - 0.00025 20.6 0.0 0.00046 19.7 0.0 1.4 1 0 0 1 1 1 1 XPG domain containing 5_3_exonuc PF01367.20 OAG38829.1 - 0.013 16.0 0.0 0.045 14.4 0.0 1.8 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold Tma16 PF11176.8 OAG38830.1 - 2.3e-45 154.0 2.3 2.9e-45 153.7 2.3 1.1 1 0 0 1 1 1 1 Translation machinery-associated protein 16 DUF769 PF05590.11 OAG38830.1 - 0.13 11.7 0.1 0.15 11.5 0.1 1.2 1 0 0 1 1 1 0 Xylella fastidiosa protein of unknown function (DUF769) MAM33 PF02330.16 OAG38831.1 - 5.7e-62 209.4 0.6 7.8e-62 209.0 0.6 1.1 1 0 0 1 1 1 1 Mitochondrial glycoprotein p450 PF00067.22 OAG38832.1 - 1e-53 182.7 0.0 2.2e-53 181.6 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 CHAT PF12770.7 OAG38834.1 - 1.6e-31 109.8 0.2 3.8e-31 108.6 0.2 1.7 1 0 0 1 1 1 1 CHAT domain TPR_12 PF13424.6 OAG38834.1 - 0.00047 20.4 19.2 3 8.2 0.0 7.9 6 3 4 10 10 10 3 Tetratricopeptide repeat TPR_10 PF13374.6 OAG38834.1 - 0.0059 16.4 27.5 1.6 8.7 0.0 9.2 10 1 0 10 10 10 2 Tetratricopeptide repeat ER PF01133.17 OAG38834.1 - 0.0087 16.1 0.0 0.84 9.7 0.0 3.2 3 0 0 3 3 3 1 Enhancer of rudimentary DUF2388 PF09498.10 OAG38834.1 - 0.019 15.0 0.5 0.72 9.9 0.2 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2388) DUF1079 PF06435.11 OAG38834.1 - 0.03 14.5 1.4 3 8.2 0.0 3.0 2 0 0 2 2 2 0 Repeat of unknown function (DUF1079) TPR_2 PF07719.17 OAG38834.1 - 0.034 14.3 0.1 3.4 8.0 0.0 4.2 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 OAG38834.1 - 0.051 13.3 0.6 1.8 8.3 0.0 3.7 5 0 0 5 5 5 0 TPR repeat SMBP PF16785.5 OAG38834.1 - 0.056 13.7 14.1 0.71 10.1 0.0 5.5 5 1 1 6 6 5 0 Small metal-binding protein TPR_14 PF13428.6 OAG38834.1 - 0.076 13.9 6.6 1.7 9.6 0.0 5.9 6 0 0 6 6 5 0 Tetratricopeptide repeat RXLR_WY PF18634.1 OAG38834.1 - 0.17 11.8 1.1 0.47 10.4 0.1 2.2 2 0 0 2 2 2 0 RXLR phytopathogen effector protein WY-domain DDRGK PF09756.9 OAG38834.1 - 1.1 8.9 7.2 1.6 8.3 1.1 2.5 2 0 0 2 2 2 0 DDRGK domain Peptidase_C14 PF00656.22 OAG38835.1 - 2.7e-23 83.2 0.0 4.3e-23 82.5 0.0 1.3 1 0 0 1 1 1 1 Caspase domain Peptidase_C13 PF01650.18 OAG38835.1 - 0.011 15.3 0.0 0.023 14.2 0.0 1.5 1 1 0 1 1 1 0 Peptidase C13 family CHAT PF12770.7 OAG38835.1 - 0.049 13.0 0.0 0.084 12.3 0.0 1.3 1 0 0 1 1 1 0 CHAT domain DIOX_N PF14226.6 OAG38836.1 - 2.3e-28 99.3 0.0 3.6e-28 98.7 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OAG38836.1 - 2.5e-17 63.2 0.0 3.9e-17 62.6 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF917 PF06032.12 OAG38837.1 - 4.1e-113 377.8 1.9 8.7e-113 376.7 1.9 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF917) Hydant_A_N PF05378.13 OAG38837.1 - 1.9e-30 105.9 0.0 4.6e-29 101.4 0.0 2.8 3 0 0 3 3 3 1 Hydantoinase/oxoprolinase N-terminal region Hydantoinase_A PF01968.18 OAG38837.1 - 3.5e-20 72.4 6.1 1.4e-16 60.6 0.2 4.2 3 1 0 3 3 3 2 Hydantoinase/oxoprolinase ROK PF00480.20 OAG38837.1 - 0.0068 15.9 0.5 0.019 14.5 0.5 1.7 1 0 0 1 1 1 1 ROK family Radical_SAM PF04055.21 OAG38837.1 - 0.06 13.7 0.1 0.19 12.1 0.1 1.8 1 0 0 1 1 1 0 Radical SAM superfamily BcrAD_BadFG PF01869.20 OAG38837.1 - 0.17 11.4 5.2 0.2 11.2 0.6 2.9 2 1 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family StbA PF06406.11 OAG38837.1 - 0.27 10.4 2.4 6.8 5.8 0.0 2.7 3 0 0 3 3 3 0 StbA protein FMO-like PF00743.19 OAG38838.1 - 2.9e-18 65.6 0.2 3.8e-17 61.9 0.2 2.2 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like GYF PF02213.16 OAG38838.1 - 4.7e-17 61.4 0.4 9.8e-17 60.4 0.4 1.6 1 0 0 1 1 1 1 GYF domain Pyr_redox_2 PF07992.14 OAG38838.1 - 6.2e-11 42.1 0.0 3.1e-08 33.2 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG38838.1 - 9.4e-11 41.5 0.0 3.8e-10 39.5 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG38838.1 - 2.7e-10 39.9 0.2 4.2e-08 32.7 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 OAG38838.1 - 9.5e-08 32.2 0.0 3.1e-07 30.5 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAG38838.1 - 1.6e-05 24.6 0.0 6.9e-05 22.6 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Shikimate_DH PF01488.20 OAG38838.1 - 0.002 18.2 0.0 0.25 11.4 0.0 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.6 OAG38838.1 - 0.01 15.8 0.1 0.2 11.6 0.0 3.1 4 0 0 4 4 4 0 FAD-NAD(P)-binding Thi4 PF01946.17 OAG38838.1 - 0.021 14.1 0.1 0.037 13.3 0.1 1.3 1 0 0 1 1 1 0 Thi4 family V-SNARE_C PF12352.8 OAG38839.1 - 9e-14 51.5 0.5 3.5e-13 49.6 0.1 2.2 2 1 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 OAG38839.1 - 0.0021 17.9 0.1 0.0067 16.3 0.0 1.9 2 1 0 2 2 2 1 Sec20 KxDL PF10241.9 OAG38839.1 - 0.0098 16.2 6.7 0.033 14.5 3.3 2.7 2 1 1 3 3 3 1 Uncharacterized conserved protein Sigma70_r4 PF04545.16 OAG38839.1 - 0.053 13.1 1.1 0.079 12.5 0.1 1.9 2 0 0 2 2 2 0 Sigma-70, region 4 DUF4698 PF15769.5 OAG38839.1 - 0.057 12.5 0.1 0.076 12.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4698) DUF4047 PF13256.6 OAG38839.1 - 0.084 13.1 0.1 0.14 12.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) DUF4407 PF14362.6 OAG38839.1 - 0.3 10.4 6.0 0.63 9.3 6.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF5353 PF17304.2 OAG38840.1 - 1.6e-32 111.0 1.4 2.1e-32 110.7 1.4 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5353) Remorin_C PF03763.13 OAG38840.1 - 0.001 18.9 5.6 0.0015 18.4 5.6 1.2 1 0 0 1 1 1 1 Remorin, C-terminal region DUF883 PF05957.13 OAG38840.1 - 0.095 13.3 0.5 0.095 13.3 0.5 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Pex19 PF04614.12 OAG38840.1 - 0.11 12.3 5.3 0.14 11.9 5.3 1.1 1 0 0 1 1 1 0 Pex19 protein family DUF4337 PF14235.6 OAG38840.1 - 1.1 9.3 6.9 1.5 8.9 6.7 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4337) YtxH PF12732.7 OAG38840.1 - 1.7 9.2 9.1 5.7 7.6 8.9 2.0 1 1 0 1 1 1 0 YtxH-like protein Aa_trans PF01490.18 OAG38841.1 - 2.9e-35 121.8 22.6 3.8e-35 121.4 22.6 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF2613 PF11021.8 OAG38841.1 - 0.0083 16.2 1.7 0.059 13.5 0.5 2.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2613) Bap31 PF05529.12 OAG38841.1 - 2.7 7.8 5.9 0.56 10.1 1.9 2.0 2 0 0 2 2 2 0 Bap31/Bap29 transmembrane region GTA_holin_3TM PF11351.8 OAG38841.1 - 3.1 8.4 4.6 2.6 8.6 0.9 2.4 2 0 0 2 2 2 0 Holin of 3TMs, for gene-transfer release 6PF2K PF01591.18 OAG38842.1 - 1.2e-75 253.7 1.0 1.7e-75 253.2 1.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 OAG38842.1 - 1e-40 139.5 0.0 1.5e-40 139.0 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) KTI12 PF08433.10 OAG38842.1 - 2.1e-07 30.7 0.1 3.3e-07 30.0 0.1 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 OAG38842.1 - 0.00025 21.2 0.0 0.00054 20.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain GRDP-like PF07173.12 OAG38844.1 - 0.36 11.5 2.1 2.2 8.9 0.3 2.5 2 0 0 2 2 2 0 Glycine-rich domain-containing protein-like DUF1127 PF06568.11 OAG38844.1 - 8.4 6.2 11.0 14 5.5 0.5 4.0 3 1 1 4 4 4 0 Domain of unknown function (DUF1127) Sugar_tr PF00083.24 OAG38845.1 - 2.2e-75 254.3 15.1 3.2e-75 253.7 15.1 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG38845.1 - 5e-12 45.4 40.4 1.8e-10 40.3 13.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily FBPase PF00316.20 OAG38846.1 - 5e-69 231.6 0.1 6.6e-69 231.2 0.1 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Cnl2_NKP2 PF09447.10 OAG38847.1 - 3e-20 72.1 0.7 5.8e-20 71.2 0.7 1.5 1 0 0 1 1 1 1 Cnl2/NKP2 family protein DUF3135 PF11333.8 OAG38847.1 - 0.006 16.8 0.1 0.014 15.6 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3135) HalX PF08663.10 OAG38847.1 - 0.015 15.6 0.1 0.063 13.6 0.1 2.1 1 0 0 1 1 1 0 HalX domain TMF_TATA_bd PF12325.8 OAG38847.1 - 0.051 13.8 2.2 0.86 9.8 0.1 2.9 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding Methyltransf_32 PF13679.6 OAG38847.1 - 0.15 12.1 0.1 0.26 11.2 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase domain Tudor-knot PF11717.8 OAG38848.1 - 2e-06 27.6 0.7 4.5e-06 26.5 0.7 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain VWA_N2 PF16164.5 OAG38848.1 - 0.023 14.8 1.5 0.065 13.4 1.5 1.7 1 0 0 1 1 1 0 VWA N-terminal Zn_clus PF00172.18 OAG38848.1 - 0.77 9.9 7.2 1.6 8.9 6.7 1.8 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Mitofilin PF09731.9 OAG38848.1 - 0.95 8.2 14.6 1.6 7.5 14.6 1.3 1 0 0 1 1 1 0 Mitochondrial inner membrane protein MRG PF05712.13 OAG38849.1 - 2.1e-56 190.4 0.0 2.3e-56 190.2 0.0 1.0 1 0 0 1 1 1 1 MRG Aha1_N PF09229.11 OAG38850.1 - 1.2e-40 138.9 0.2 2.6e-40 137.8 0.1 1.6 2 0 0 2 2 2 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 OAG38850.1 - 4.2e-19 69.0 0.8 7e-19 68.3 0.8 1.4 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein DUF726 PF05277.12 OAG38851.1 - 5.2e-123 410.3 2.2 9.2e-123 409.5 2.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Thioesterase PF00975.20 OAG38851.1 - 0.043 13.9 0.7 0.19 11.8 0.0 2.4 2 1 0 2 2 2 0 Thioesterase domain Phage_holin_3_6 PF07332.11 OAG38851.1 - 0.81 9.7 5.5 0.55 10.3 2.7 2.2 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III CRF PF00473.17 OAG38851.1 - 4.5 7.4 4.9 4.3 7.5 1.8 2.7 2 0 0 2 2 2 0 Corticotropin-releasing factor family DUF4097 PF13349.6 OAG38852.1 - 5.9e-09 35.6 1.7 1.1e-07 31.5 1.7 2.1 1 1 0 1 1 1 1 Putative adhesin ATP-synt_ab_Xtn PF16886.5 OAG38852.1 - 0.015 15.2 0.1 0.043 13.7 0.0 1.7 2 0 0 2 2 2 0 ATPsynthase alpha/beta subunit N-term extension 4HBT PF03061.22 OAG38854.1 - 6.8e-10 39.2 0.3 6.8e-10 39.2 0.3 1.6 2 0 0 2 2 2 1 Thioesterase superfamily 4HBT_3 PF13622.6 OAG38854.1 - 1.6e-07 31.9 0.1 2.6e-07 31.1 0.0 1.4 2 0 0 2 2 2 1 Thioesterase-like superfamily Cutinase PF01083.22 OAG38855.1 - 1.6e-25 90.1 0.3 1.6e-25 90.1 0.3 2.1 2 0 0 2 2 2 1 Cutinase DIOX_N PF14226.6 OAG38856.1 - 1.5e-20 74.1 0.2 3.7e-20 72.8 0.1 1.7 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OAG38856.1 - 4e-16 59.3 0.1 8.3e-16 58.3 0.1 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Syntaxin-18_N PF10496.9 OAG38856.1 - 0.048 13.9 0.1 0.094 13.0 0.1 1.5 1 0 0 1 1 1 0 SNARE-complex protein Syntaxin-18 N-terminus DUF4227 PF14004.6 OAG38856.1 - 0.19 11.7 0.2 7.9 6.5 0.0 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF4227) adh_short PF00106.25 OAG38857.1 - 1.9e-36 125.4 0.0 2.6e-36 124.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG38857.1 - 1.5e-30 106.5 0.0 2.1e-30 106.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG38857.1 - 0.0034 17.3 0.2 0.057 13.3 0.2 2.1 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG38857.1 - 0.088 12.3 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Exotox-A_bind PF09101.10 OAG38857.1 - 0.22 10.8 0.0 0.33 10.2 0.0 1.2 1 0 0 1 1 1 0 Exotoxin A binding Fungal_trans PF04082.18 OAG38858.1 - 7.6e-10 38.3 0.0 1.5e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short_C2 PF13561.6 OAG38859.1 - 4.8e-50 170.3 0.0 1.5e-48 165.4 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG38859.1 - 1e-36 126.3 0.9 4.8e-36 124.1 0.9 1.8 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG38859.1 - 1.1e-06 28.7 0.2 1.5e-06 28.2 0.2 1.2 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 OAG38859.1 - 0.018 14.0 0.2 0.027 13.5 0.2 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 OAG38859.1 - 0.03 13.8 0.2 0.058 12.8 0.1 1.5 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family FMO-like PF00743.19 OAG38860.1 - 9.7e-08 30.9 0.2 0.0015 17.1 0.1 3.1 2 1 1 3 3 3 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 OAG38860.1 - 8.9e-07 28.4 0.5 1.2 8.1 0.0 4.1 4 0 0 4 4 4 3 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 OAG38860.1 - 3.8e-06 27.0 0.0 1.1e-05 25.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAG38860.1 - 4.1e-05 22.9 0.0 0.0014 17.9 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAG38860.1 - 0.033 14.2 0.0 0.24 11.4 0.0 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 OAG38860.1 - 0.062 12.5 0.0 0.16 11.2 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAG38860.1 - 0.16 11.5 0.0 0.56 9.7 0.0 2.0 2 1 0 2 2 2 0 FAD dependent oxidoreductase adh_short PF00106.25 OAG38861.1 - 4e-32 111.3 0.0 5.5e-32 110.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG38861.1 - 9.6e-29 100.6 0.0 1.3e-28 100.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 3HCDH_N PF02737.18 OAG38861.1 - 0.0056 16.6 0.1 0.0088 15.9 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_25 PF13649.6 OAG38861.1 - 0.034 14.9 0.1 0.12 13.1 0.1 1.9 2 0 0 2 2 2 0 Methyltransferase domain KR PF08659.10 OAG38861.1 - 0.068 13.1 0.1 0.61 10.0 0.1 2.2 1 1 0 1 1 1 0 KR domain Epimerase PF01370.21 OAG38861.1 - 0.091 12.2 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Beta-lactamase PF00144.24 OAG38862.1 - 1.5e-25 90.2 0.0 6.1e-13 48.7 0.0 2.3 1 1 1 2 2 2 2 Beta-lactamase Beta-lactamase2 PF13354.6 OAG38862.1 - 0.015 14.9 0.0 0.032 13.8 0.0 1.5 1 1 0 1 1 1 0 Beta-lactamase enzyme family FMO-like PF00743.19 OAG38863.1 - 8.9e-11 40.9 0.1 1.5e-09 36.8 0.0 2.3 1 1 1 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 OAG38863.1 - 3.9e-08 32.8 0.6 0.00077 18.7 0.1 3.1 1 1 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 OAG38863.1 - 1.8e-06 28.1 0.0 3.7e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAG38863.1 - 1.3e-05 24.6 0.0 0.00075 18.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG38863.1 - 0.00013 21.3 0.0 0.03 13.6 0.0 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAG38863.1 - 0.00022 21.2 0.3 0.003 17.5 0.0 2.6 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.24 OAG38863.1 - 0.00049 19.8 2.1 0.0066 16.1 0.4 3.3 2 1 1 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.17 OAG38863.1 - 0.0057 15.9 0.0 0.021 14.1 0.0 1.8 2 0 0 2 2 2 1 Thi4 family DUF2065 PF09838.9 OAG38863.1 - 0.18 11.8 0.1 0.4 10.7 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2065) Cyclase PF04199.13 OAG38864.1 - 3.3e-11 43.6 0.6 6.6e-11 42.6 0.5 1.5 1 1 0 1 1 1 1 Putative cyclase AtuA PF07287.11 OAG38865.1 - 3.4e-122 407.5 0.0 4.5e-122 407.1 0.0 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA Fungal_trans PF04082.18 OAG38866.1 - 3.5e-16 59.0 0.2 5.4e-16 58.4 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain p450 PF00067.22 OAG38867.1 - 4.2e-46 157.6 0.0 8e-46 156.7 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 NEMO PF11577.8 OAG38867.1 - 0.12 12.4 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 NF-kappa-B essential modulator NEMO DUF4363 PF14276.6 OAG38867.1 - 0.16 12.1 1.3 0.29 11.3 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4363) Sugar_tr PF00083.24 OAG38868.1 - 4.2e-73 246.7 26.6 4.7e-73 246.6 26.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG38868.1 - 1.4e-24 86.7 39.2 1.7e-21 76.5 26.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Acyl-CoA_dh_M PF02770.19 OAG38869.1 - 2.9e-11 43.4 0.1 5e-11 42.7 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 OAG38869.1 - 4.2e-05 24.2 0.0 0.00011 22.9 0.0 1.8 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Cyt-b5 PF00173.28 OAG38869.1 - 0.00034 20.7 0.0 0.0014 18.8 0.0 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FMO-like PF00743.19 OAG38870.1 - 2.3e-17 62.6 1.4 5.2e-15 54.9 0.2 2.8 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OAG38870.1 - 4.2e-11 42.9 0.0 4.2e-11 42.9 0.0 2.2 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAG38870.1 - 2.1e-10 40.3 0.0 2.4e-07 30.3 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG38870.1 - 6.1e-10 38.8 0.3 2.5e-08 33.4 0.0 2.7 4 0 0 4 4 4 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 OAG38870.1 - 7.3e-07 29.1 0.9 0.068 12.7 0.1 3.3 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 OAG38870.1 - 1e-06 28.9 0.1 0.00015 21.8 0.0 3.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 OAG38870.1 - 2.2e-06 27.2 0.0 0.00022 20.6 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAG38870.1 - 0.027 15.0 0.6 5 7.8 0.0 3.0 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.15 OAG38870.1 - 0.29 9.7 0.4 12 4.3 0.1 2.2 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) GIDA PF01134.22 OAG38870.1 - 1.9 7.5 4.2 46 2.9 0.0 3.3 4 0 0 4 4 4 0 Glucose inhibited division protein A Sugar_tr PF00083.24 OAG38871.1 - 3.6e-83 279.9 15.1 4.5e-83 279.6 15.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG38871.1 - 9.1e-20 70.9 29.9 9.1e-20 70.9 29.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Cyclin_C_2 PF16899.5 OAG38872.1 - 4.6e-27 94.4 0.2 7.7e-23 80.9 0.0 2.5 2 0 0 2 2 2 2 Cyclin C-terminal domain Cyclin_N PF00134.23 OAG38872.1 - 1.7e-06 27.8 0.0 2.9e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain adh_short PF00106.25 OAG38873.1 - 1.3e-42 145.5 0.0 1.8e-42 145.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG38873.1 - 1.6e-32 113.0 0.0 2.1e-32 112.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG38873.1 - 9.5e-05 22.4 0.1 0.00072 19.5 0.0 2.1 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 OAG38873.1 - 0.0065 16.0 0.0 0.0096 15.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family B12-binding PF02310.19 OAG38873.1 - 0.0093 16.0 0.0 0.021 14.9 0.0 1.6 1 0 0 1 1 1 1 B12 binding domain NAD_binding_10 PF13460.6 OAG38873.1 - 0.013 15.4 0.0 0.018 15.0 0.0 1.2 1 0 0 1 1 1 0 NAD(P)H-binding TrkA_N PF02254.18 OAG38873.1 - 0.024 14.9 0.0 0.042 14.1 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain Shikimate_DH PF01488.20 OAG38873.1 - 0.059 13.4 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ADH_zinc_N PF00107.26 OAG38873.1 - 0.14 12.1 0.2 0.45 10.5 0.1 1.8 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Pyr_redox_3 PF13738.6 OAG38874.1 - 5.1e-15 55.5 0.0 1.3e-12 47.6 0.0 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 OAG38874.1 - 3.2e-11 42.3 0.0 2.1e-09 36.4 0.0 2.6 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 OAG38874.1 - 3.5e-10 39.6 0.0 4e-06 26.3 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG38874.1 - 3.5e-07 29.7 0.0 0.00033 19.9 0.0 2.7 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 OAG38874.1 - 7.2e-06 26.1 2.2 7.2e-06 26.1 0.0 2.2 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.20 OAG38874.1 - 9.1e-06 25.8 0.0 0.19 11.8 0.0 2.5 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 OAG38874.1 - 0.00011 21.5 0.0 0.014 14.6 0.1 2.3 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 OAG38874.1 - 0.0096 15.5 0.3 1.1 8.7 0.1 3.1 2 1 1 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OAG38874.1 - 0.037 13.1 0.0 0.065 12.3 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain ThiF PF00899.21 OAG38874.1 - 0.086 12.2 0.0 5.4 6.3 0.0 2.3 2 0 0 2 2 2 0 ThiF family NAD_binding_4 PF07993.12 OAG38875.1 - 5.8e-73 245.2 0.0 8.9e-73 244.6 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 OAG38875.1 - 1e-69 235.2 0.0 3.1e-69 233.6 0.0 1.8 2 0 0 2 2 2 1 AMP-binding enzyme Epimerase PF01370.21 OAG38875.1 - 1.2e-08 34.8 0.0 2.1e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Condensation PF00668.20 OAG38875.1 - 6.1e-08 31.8 0.0 7.1e-07 28.3 0.0 2.4 1 1 0 1 1 1 1 Condensation domain 3Beta_HSD PF01073.19 OAG38875.1 - 2.4e-07 30.1 0.0 1.1e-06 27.9 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family PP-binding PF00550.25 OAG38875.1 - 1.9e-06 28.1 0.0 5.4e-06 26.7 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.6 OAG38875.1 - 2.1e-06 28.6 0.0 1.4e-05 26.0 0.0 2.4 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Polysacc_synt_2 PF02719.15 OAG38875.1 - 0.03 13.4 0.0 0.65 9.1 0.0 2.2 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 OAG38875.1 - 0.094 12.6 0.0 1.7 8.5 0.0 2.5 1 1 0 1 1 1 0 NAD(P)H-binding Pkinase_Tyr PF07714.17 OAG38877.1 - 2.7e-08 33.4 0.0 5.1e-07 29.2 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OAG38877.1 - 2e-07 30.7 0.0 3.1e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 OAG38877.1 - 0.0045 17.0 0.0 0.0062 16.5 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 OAG38877.1 - 0.15 11.7 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Sugar_tr PF00083.24 OAG38879.1 - 1.8e-93 313.8 16.1 2.4e-93 313.5 16.1 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG38879.1 - 1.1e-10 41.0 41.8 9.2e-06 24.8 14.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PRAI PF00697.22 OAG38879.1 - 0.24 11.1 0.0 0.36 10.6 0.0 1.2 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase SNF2_N PF00176.23 OAG38880.1 - 5.7e-65 219.3 0.2 9.9e-65 218.5 0.2 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OAG38880.1 - 4.7e-20 72.0 0.5 1.3e-18 67.3 0.1 3.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG38880.1 - 5.8e-10 39.4 1.3 1.3e-09 38.3 0.0 2.3 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit HSA PF07529.13 OAG38880.1 - 5.7e-07 29.8 16.3 8.5e-07 29.2 14.3 2.5 2 0 0 2 2 2 1 HSA DEAD PF00270.29 OAG38880.1 - 1.1e-05 25.3 0.0 4e-05 23.5 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase DEAD_2 PF06733.15 OAG38880.1 - 0.074 12.7 0.4 0.22 11.1 0.0 2.0 2 0 0 2 2 2 0 DEAD_2 NDUF_B8 PF05821.11 OAG38881.1 - 2.2e-10 40.7 0.1 2.8e-10 40.3 0.1 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) DUF4988 PF16378.5 OAG38882.1 - 0.091 12.4 0.2 0.14 11.8 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function zf-Mss51 PF13824.6 OAG38883.1 - 3.6e-29 100.6 5.7 6.4e-29 99.8 5.7 1.4 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.18 OAG38883.1 - 0.00041 20.4 0.3 0.00077 19.5 0.3 1.4 1 0 0 1 1 1 1 MYND finger DUF4902 PF16245.5 OAG38883.1 - 0.16 11.9 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4902) APH PF01636.23 OAG38885.1 - 5e-13 49.5 0.0 3.4e-12 46.8 0.0 2.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Transp_cyt_pur PF02133.15 OAG38886.1 - 8.6e-85 285.1 39.9 1.4e-77 261.3 35.5 2.0 2 0 0 2 2 2 2 Permease for cytosine/purines, uracil, thiamine, allantoin adh_short PF00106.25 OAG38887.1 - 5.5e-42 143.4 0.0 8.9e-42 142.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG38887.1 - 1.7e-27 96.5 0.0 2.4e-27 96.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG38887.1 - 2.1e-06 27.8 0.0 3e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 OAG38887.1 - 0.00025 20.5 0.0 0.00031 20.2 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.6 OAG38887.1 - 0.0016 18.4 0.1 0.0073 16.2 0.0 2.0 2 0 0 2 2 2 1 NAD(P)H-binding NAD_binding_10 PF13460.6 OAG38888.1 - 1.2e-14 54.6 0.0 1.9e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 OAG38888.1 - 6.3e-14 52.1 0.0 9.3e-12 45.0 0.1 2.1 2 0 0 2 2 2 2 NmrA-like family Epimerase PF01370.21 OAG38888.1 - 1.3e-06 28.0 1.1 0.0002 20.9 0.4 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 OAG38888.1 - 0.00026 21.3 0.2 0.00045 20.5 0.2 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain DapB_N PF01113.20 OAG38888.1 - 0.0013 18.9 1.0 0.0059 16.7 1.0 1.9 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus KR PF08659.10 OAG38888.1 - 0.003 17.5 0.1 0.0058 16.6 0.1 1.4 1 0 0 1 1 1 1 KR domain TrkA_N PF02254.18 OAG38888.1 - 0.011 16.0 0.3 0.018 15.3 0.3 1.3 1 0 0 1 1 1 0 TrkA-N domain Semialdhyde_dh PF01118.24 OAG38888.1 - 0.036 14.5 0.1 0.062 13.7 0.1 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain PglD_N PF17836.1 OAG38888.1 - 0.06 14.0 0.0 0.14 12.8 0.0 1.6 1 0 0 1 1 1 0 PglD N-terminal domain DXP_reductoisom PF02670.16 OAG38888.1 - 0.087 13.5 0.2 0.35 11.6 0.1 1.9 1 1 1 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase RmlD_sub_bind PF04321.17 OAG38888.1 - 0.14 11.2 0.1 0.21 10.7 0.1 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Ifi-6-16 PF06140.13 OAG38890.1 - 0.0088 15.9 15.4 0.0088 15.9 15.4 3.1 1 1 2 3 3 3 2 Interferon-induced 6-16 family ADH_zinc_N PF00107.26 OAG38891.1 - 3.3e-30 104.7 0.2 5.4e-30 104.0 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAG38891.1 - 1.2e-11 45.8 0.0 2.1e-11 45.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG38891.1 - 1.4e-05 24.9 0.1 0.00012 21.9 0.0 2.6 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain HupF_HypC PF01455.18 OAG38891.1 - 0.0075 16.4 0.6 0.034 14.3 0.3 2.2 1 1 1 2 2 2 1 HupF/HypC family AlaDh_PNT_C PF01262.21 OAG38891.1 - 0.018 14.4 1.1 0.027 13.8 1.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Ribonuc_L-PSP PF01042.21 OAG38892.1 - 2.8e-39 133.9 0.0 3.1e-39 133.7 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP CoA_transf_3 PF02515.17 OAG38893.1 - 3.2e-108 362.1 0.0 3.9e-108 361.9 0.0 1.1 1 0 0 1 1 1 1 CoA-transferase family III TRI12 PF06609.13 OAG38893.1 - 8.9e-16 57.4 9.2 2.2e-07 29.7 4.4 3.0 1 1 2 3 3 3 3 Fungal trichothecene efflux pump (TRI12) Abhydrolase_3 PF07859.13 OAG38895.1 - 1.6e-52 178.4 0.0 2e-52 178.1 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 OAG38895.1 - 0.00042 19.3 0.1 0.001 18.1 0.1 1.5 1 1 0 1 1 1 1 Carboxylesterase family DLH PF01738.18 OAG38895.1 - 0.0015 18.1 0.0 0.016 14.8 0.0 2.2 2 0 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 OAG38895.1 - 0.0046 16.5 0.1 0.049 13.1 0.1 2.4 2 1 0 2 2 2 1 Prolyl oligopeptidase family Abhydro_lipase PF04083.16 OAG38895.1 - 0.076 12.6 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region AXE1 PF05448.12 OAG38895.1 - 0.077 11.7 0.0 0.15 10.7 0.0 1.4 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) AtuA PF07287.11 OAG38896.1 - 3.3e-14 52.4 0.0 4.2e-14 52.0 0.0 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA Fungal_trans PF04082.18 OAG38897.1 - 2.1e-13 49.9 0.1 4.2e-13 48.9 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain CPSase_L_D2 PF02786.17 OAG38898.1 - 1.7e-66 223.7 0.0 2.5e-66 223.2 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 OAG38898.1 - 2.2e-36 124.8 0.1 8.4e-36 122.9 0.0 2.0 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 OAG38898.1 - 7.5e-33 112.9 0.0 1.8e-32 111.7 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 OAG38898.1 - 8.7e-12 44.7 0.9 2.1e-11 43.5 0.9 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 OAG38898.1 - 7.5e-09 35.4 0.0 1.4e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 OAG38898.1 - 5.1e-07 29.4 0.1 1.5e-06 27.9 0.0 1.7 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_3 PF02655.14 OAG38898.1 - 1.5e-05 25.1 0.0 3.8e-05 23.8 0.0 1.7 2 0 0 2 2 2 1 ATP-grasp domain DUF3182 PF11379.8 OAG38898.1 - 0.0061 15.6 0.0 0.01 14.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3182) PK_C PF02887.16 OAG38898.1 - 0.056 13.7 0.2 0.51 10.6 0.2 2.5 3 0 0 3 3 3 0 Pyruvate kinase, alpha/beta domain Carboxyl_trans PF01039.22 OAG38899.1 - 3.3e-96 322.9 0.0 7.8e-60 202.9 0.0 2.0 2 0 0 2 2 2 2 Carboxyl transferase domain HMGL-like PF00682.19 OAG38900.1 - 7.3e-52 176.5 0.0 1.2e-51 175.9 0.0 1.3 1 0 0 1 1 1 1 HMGL-like ECH_1 PF00378.20 OAG38900.1 - 2.2e-40 138.6 0.3 3.8e-40 137.8 0.0 1.6 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAG38900.1 - 8e-31 107.8 0.0 1.1e-30 107.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase FlbD PF06289.11 OAG38900.1 - 0.17 11.5 0.0 0.49 10.0 0.0 1.8 1 0 0 1 1 1 0 Flagellar and Swarming motility proteins Acyl-CoA_dh_1 PF00441.24 OAG38901.1 - 2.8e-27 95.8 0.4 3.7e-27 95.4 0.4 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 OAG38901.1 - 2.8e-25 88.3 0.2 4.7e-25 87.6 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 OAG38901.1 - 3.5e-23 82.4 0.0 2.9e-22 79.5 0.0 2.3 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain AMP-binding PF00501.28 OAG38902.1 - 4.6e-90 302.2 0.0 6.1e-90 301.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG38902.1 - 2e-11 44.7 0.9 4.5e-11 43.6 0.3 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Fungal_trans PF04082.18 OAG38903.1 - 9.8e-12 44.4 0.1 1.7e-11 43.7 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAD_binding_4 PF01565.23 OAG38904.1 - 5.3e-27 94.3 0.0 1e-26 93.3 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.19 OAG38904.1 - 5e-19 68.9 0.0 7.1e-19 68.4 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain ADSL_C PF10397.9 OAG38904.1 - 0.13 12.8 0.0 0.42 11.2 0.0 1.8 1 0 0 1 1 1 0 Adenylosuccinate lyase C-terminus p450 PF00067.22 OAG38905.1 - 1.8e-73 247.9 0.0 2.2e-73 247.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ADH_N PF08240.12 OAG38907.1 - 2.1e-30 104.8 0.5 3.9e-30 103.9 0.5 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG38907.1 - 2.3e-16 60.0 0.0 4e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 OAG38907.1 - 3.5e-07 29.9 0.1 9e-07 28.6 0.1 1.6 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 OAG38907.1 - 1.5e-05 24.4 0.1 2.3e-05 23.8 0.1 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.6 OAG38907.1 - 0.00034 21.7 0.0 0.00067 20.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AMP-binding PF00501.28 OAG38908.1 - 6.5e-65 219.4 0.5 2.8e-35 121.7 0.0 4.3 2 2 0 2 2 2 2 AMP-binding enzyme DMAP_binding PF06464.11 OAG38908.1 - 3.7e-10 40.6 0.1 2.3e-09 38.1 0.1 2.3 2 0 0 2 2 2 1 DMAP1-binding Domain Pribosyltran PF00156.27 OAG38909.1 - 6e-12 45.4 0.0 8.3e-12 44.9 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 OAG38909.1 - 0.056 12.9 0.0 0.076 12.4 0.0 1.2 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase DUF4148 PF13663.6 OAG38909.1 - 0.24 11.6 0.8 0.4 10.9 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) DEAD PF00270.29 OAG38910.1 - 2.9e-46 157.4 0.2 9.1e-46 155.8 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAG38910.1 - 3.5e-27 95.0 0.7 2.7e-25 88.9 0.2 3.3 4 0 0 4 4 4 1 Helicase conserved C-terminal domain UTP25 PF06862.12 OAG38910.1 - 0.021 13.6 0.7 1.9 7.2 0.0 3.0 3 1 1 4 4 4 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Trp_repressor PF01371.19 OAG38910.1 - 0.045 13.9 0.4 0.11 12.7 0.4 1.6 1 0 0 1 1 1 0 Trp repressor protein AAA_22 PF13401.6 OAG38910.1 - 0.057 13.7 0.1 0.19 12.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain Phage_integrase PF00589.22 OAG38910.1 - 0.094 12.5 0.5 0.26 11.0 0.0 2.0 2 0 0 2 2 2 0 Phage integrase family PAD PF03068.15 OAG38910.1 - 0.45 9.5 6.1 0.67 8.9 0.5 2.2 2 0 0 2 2 2 0 Protein-arginine deiminase (PAD) MCPsignal PF00015.21 OAG38910.1 - 0.48 10.2 10.8 0.012 15.4 3.8 1.8 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Abhydrolase_6 PF12697.7 OAG38911.1 - 2.3e-23 84.0 0.1 4.2e-23 83.1 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAG38911.1 - 1.1e-11 44.9 0.1 5.3e-11 42.7 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAG38911.1 - 2e-07 30.6 0.0 3.1e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 OAG38911.1 - 0.025 14.3 0.0 0.041 13.6 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Peptidase_S9 PF00326.21 OAG38911.1 - 0.028 13.9 0.0 6.3 6.2 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family LIDHydrolase PF10230.9 OAG38911.1 - 0.038 13.6 0.0 0.06 12.9 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase DLH PF01738.18 OAG38911.1 - 0.04 13.5 0.0 2.9 7.4 0.0 2.3 2 0 0 2 2 2 0 Dienelactone hydrolase family Abhydrolase_5 PF12695.7 OAG38911.1 - 0.066 13.0 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2417 PF10329.9 OAG38912.1 - 3.7e-81 272.0 0.6 5.1e-81 271.6 0.6 1.1 1 0 0 1 1 1 1 Region of unknown function (DUF2417) Spo7 PF03907.13 OAG38912.1 - 0.00077 19.0 1.5 0.00077 19.0 1.5 1.7 2 0 0 2 2 2 1 Spo7-like protein DUF2070 PF09843.9 OAG38912.1 - 0.013 13.8 9.9 0.018 13.3 9.9 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Trp_oprn_chp PF09534.10 OAG38912.1 - 1.6 8.5 7.9 1.3 8.8 5.3 2.0 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF4267 PF14087.6 OAG38912.1 - 1.7 8.8 5.3 1.7 8.7 2.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4267) DuoxA PF10204.9 OAG38912.1 - 2.9 6.8 9.6 0.065 12.2 2.3 1.9 1 1 1 2 2 2 0 Dual oxidase maturation factor NPL4 PF05021.15 OAG38913.1 - 1.4e-134 448.3 0.0 1.8e-134 448.0 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.15 OAG38913.1 - 2.8e-71 238.3 0.3 4.1e-71 237.8 0.3 1.2 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.8 OAG38913.1 - 0.049 14.1 0.0 0.61 10.6 0.0 2.3 1 1 0 1 1 1 0 Nuclear pore localisation protein NPL4 DUF2729 PF10870.8 OAG38913.1 - 0.19 11.6 0.0 1.2 9.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2729) PDEase_I PF00233.19 OAG38914.1 - 1.1e-66 225.0 0.0 2e-66 224.1 0.0 1.5 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase SGL PF08450.12 OAG38915.1 - 5.8e-69 232.4 0.2 7.1e-69 232.1 0.2 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region DUF5074 PF16819.5 OAG38915.1 - 0.0096 16.0 0.0 0.15 12.1 0.0 2.4 1 1 1 2 2 2 1 Domain of unknown function (DUF5074) Arylesterase PF01731.20 OAG38915.1 - 0.15 12.2 0.0 0.5 10.6 0.0 1.8 2 0 0 2 2 2 0 Arylesterase UBA_4 PF14555.6 OAG38916.1 - 0.065 13.1 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 UBA-like domain DAHP_synth_2 PF01474.16 OAG38917.1 - 2.4e-191 636.0 0.0 2e-190 633.0 0.0 1.9 1 1 0 1 1 1 1 Class-II DAHP synthetase family Glyco_hydro_17 PF00332.18 OAG38919.1 - 8.2e-05 22.3 1.9 0.00018 21.2 0.8 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 17 Acyl-CoA_dh_1 PF00441.24 OAG38920.1 - 2.6e-41 141.3 0.3 3.7e-41 140.8 0.3 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 OAG38920.1 - 1.3e-20 73.3 0.1 2.3e-20 72.6 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 OAG38920.1 - 3.8e-19 69.4 0.0 8.8e-19 68.2 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Cyt-b5 PF00173.28 OAG38920.1 - 2.2e-13 50.2 0.2 3.9e-13 49.3 0.2 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_2 PF08028.11 OAG38920.1 - 3.2e-09 37.2 0.0 4.9e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain RecG_wedge PF17191.4 OAG38920.1 - 0.055 13.1 0.1 0.093 12.3 0.1 1.3 1 0 0 1 1 1 0 RecG wedge domain Kelch_3 PF13415.6 OAG38921.1 - 1.8e-14 53.6 2.1 1.1e-08 35.1 0.0 5.3 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_5 PF13854.6 OAG38921.1 - 5.2e-14 51.8 3.8 2.4e-05 24.2 0.0 4.0 4 0 0 4 4 4 3 Kelch motif Kelch_4 PF13418.6 OAG38921.1 - 3.5e-13 49.3 2.1 8.5e-05 22.5 0.0 4.9 4 1 0 4 4 4 2 Galactose oxidase, central domain Kelch_6 PF13964.6 OAG38921.1 - 2.6e-12 46.6 6.5 0.0071 16.6 0.0 5.7 3 1 1 4 4 4 3 Kelch motif Kelch_1 PF01344.25 OAG38921.1 - 1.6e-09 37.2 0.2 0.0061 16.1 0.0 4.7 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.15 OAG38921.1 - 1.8e-07 30.8 3.9 0.00018 21.3 0.0 4.8 5 1 0 5 5 5 2 Kelch motif BTB PF00651.31 OAG38921.1 - 0.0017 18.6 0.1 0.18 12.0 0.0 2.5 3 0 0 3 3 3 1 BTB/POZ domain AhpC-TSA PF00578.21 OAG38922.1 - 6.6e-31 106.8 0.0 9.6e-31 106.3 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 OAG38922.1 - 1.3e-13 50.9 0.0 1.7e-13 50.5 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 OAG38922.1 - 4.8e-12 45.5 0.3 9.1e-12 44.6 0.3 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Ank_5 PF13857.6 OAG38923.1 - 1.4e-10 41.2 0.9 2.8e-07 30.7 0.3 2.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 OAG38923.1 - 1.6e-09 38.2 0.0 3e-09 37.4 0.0 1.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAG38923.1 - 1.3e-07 32.1 0.1 0.013 16.0 0.0 3.1 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG38923.1 - 4.9e-07 29.6 0.0 0.001 19.3 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 OAG38923.1 - 2.8e-06 27.5 0.8 0.00033 21.0 0.5 2.4 2 0 0 2 2 2 1 Ankyrin repeat eIF-4B PF06273.11 OAG38924.1 - 0.026 13.6 0.7 0.031 13.3 0.7 1.1 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B GMC_oxred_N PF00732.19 OAG38925.1 - 7.9e-68 229.0 0.0 1.2e-67 228.4 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAG38925.1 - 1.1e-36 126.5 0.0 2e-36 125.7 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 OAG38925.1 - 1.2e-06 27.9 0.9 0.0004 19.6 0.3 2.4 3 0 0 3 3 3 2 FAD binding domain DAO PF01266.24 OAG38925.1 - 1.3e-05 24.9 0.5 0.0015 18.2 0.2 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG38925.1 - 3.4e-05 23.2 0.0 0.016 14.4 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OAG38925.1 - 4.4e-05 22.7 0.2 7.4e-05 22.0 0.2 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 OAG38925.1 - 9.6e-05 22.5 0.1 0.00023 21.3 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 OAG38925.1 - 0.00059 19.1 0.0 0.0015 17.9 0.0 1.6 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 OAG38925.1 - 0.011 15.0 0.0 2 7.6 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAG38925.1 - 0.019 13.7 0.1 0.033 12.9 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.27 OAG38925.1 - 0.037 14.6 0.2 2.3 8.8 0.2 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Imm40 PF15569.6 OAG38925.1 - 0.14 12.3 0.0 0.4 10.8 0.0 1.8 1 1 0 1 1 1 0 Immunity protein 40 FAD_oxidored PF12831.7 OAG38925.1 - 0.29 10.4 0.9 15 4.8 0.0 2.4 2 0 0 2 2 2 0 FAD dependent oxidoreductase GTP_EFTU PF00009.27 OAG38926.1 - 2e-58 197.1 0.3 3.8e-58 196.2 0.3 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 OAG38926.1 - 3.4e-34 116.7 0.0 9.1e-34 115.4 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.18 OAG38926.1 - 5.7e-33 113.3 0.1 1e-32 112.4 0.1 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 OAG38926.1 - 1.1e-21 76.7 0.0 4.8e-21 74.6 0.0 2.2 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 OAG38926.1 - 8e-13 48.6 0.1 2.1e-12 47.2 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 OAG38926.1 - 2.2e-07 30.7 0.1 8.7e-07 28.8 0.0 2.0 2 0 0 2 2 2 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 OAG38926.1 - 0.11 12.6 0.0 0.27 11.3 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase Methyltransf_3 PF01596.17 OAG38928.1 - 2e-23 82.7 0.0 2.7e-23 82.3 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 OAG38928.1 - 8e-11 42.9 0.0 1.3e-10 42.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG38928.1 - 0.019 15.6 0.0 0.05 14.3 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 OAG38928.1 - 0.058 13.2 0.0 0.085 12.7 0.0 1.3 1 1 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.15 OAG38928.1 - 0.075 12.7 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 K_trans PF02705.16 OAG38929.1 - 2.5e-178 593.9 15.8 1.1e-144 482.9 16.7 2.0 2 0 0 2 2 2 2 K+ potassium transporter Syja_N PF02383.18 OAG38930.1 - 2.9e-91 306.1 0.0 3.7e-91 305.8 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain Ras PF00071.22 OAG38931.1 - 2.3e-59 199.6 0.4 2.6e-59 199.4 0.4 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAG38931.1 - 1.7e-36 125.0 0.2 4e-36 123.9 0.1 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAG38931.1 - 7.3e-15 54.9 0.1 9e-15 54.6 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OAG38931.1 - 1e-06 28.8 0.0 1.7e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OAG38931.1 - 2e-06 27.3 0.1 2.5e-06 27.0 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 OAG38931.1 - 3e-06 26.9 0.0 4.2e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OAG38931.1 - 0.0001 22.2 1.2 0.28 11.1 0.0 2.4 1 1 2 3 3 3 2 RsgA GTPase AAA_16 PF13191.6 OAG38931.1 - 0.013 15.9 0.1 0.022 15.2 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 OAG38931.1 - 0.045 14.0 0.1 2.7 8.3 0.0 2.3 1 1 1 2 2 2 0 AAA domain TniB PF05621.11 OAG38931.1 - 0.11 11.9 0.0 0.44 9.9 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein TLD PF07534.16 OAG38932.1 - 1.5e-20 73.8 0.0 3.1e-20 72.8 0.0 1.5 1 0 0 1 1 1 1 TLD DUF1773 PF08593.10 OAG38932.1 - 0.048 14.7 0.0 0.21 12.6 0.0 2.2 1 0 0 1 1 1 0 Domain of unknown function Mur_ligase_M PF08245.12 OAG38933.1 - 2.9e-05 24.1 0.8 0.00073 19.6 0.8 2.8 1 1 0 1 1 1 1 Mur ligase middle domain Kelch_5 PF13854.6 OAG38934.1 - 2.4e-14 52.9 6.7 1.3e-12 47.4 0.1 4.1 4 0 0 4 4 4 1 Kelch motif Kelch_2 PF07646.15 OAG38934.1 - 0.0013 18.6 0.4 3.2 7.9 0.0 4.5 4 0 0 4 4 4 1 Kelch motif Kelch_6 PF13964.6 OAG38934.1 - 0.0018 18.5 4.6 0.086 13.2 0.1 4.3 4 0 0 4 4 4 1 Kelch motif Kelch_4 PF13418.6 OAG38934.1 - 0.0022 18.0 9.1 0.21 11.6 0.1 5.5 5 1 0 5 5 5 1 Galactose oxidase, central domain Rax2 PF12768.7 OAG38934.1 - 0.0072 15.8 0.1 0.023 14.2 0.0 1.8 2 0 0 2 2 2 1 Cortical protein marker for cell polarity SKG6 PF08693.10 OAG38934.1 - 0.0082 15.5 0.3 0.03 13.7 0.3 2.1 1 0 0 1 1 1 1 Transmembrane alpha-helix domain EphA2_TM PF14575.6 OAG38934.1 - 0.03 15.2 0.0 0.067 14.1 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Kelch_1 PF01344.25 OAG38934.1 - 0.03 13.9 7.4 0.11 12.1 0.1 4.5 4 1 0 4 4 4 0 Kelch motif SRTM1 PF15872.5 OAG38934.1 - 0.034 14.3 0.6 0.13 12.4 0.6 1.9 1 0 0 1 1 1 0 Serine-rich and transmembrane domain-containing protein 1 Amnionless PF14828.6 OAG38934.1 - 0.084 11.7 0.0 0.19 10.6 0.0 1.5 1 0 0 1 1 1 0 Amnionless Stevor PF17410.2 OAG38934.1 - 0.21 11.1 0.0 0.32 10.5 0.0 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame RIFIN PF02009.16 OAG38934.1 - 0.26 11.2 0.1 0.42 10.5 0.1 1.2 1 0 0 1 1 1 0 Rifin Abhydrolase_1 PF00561.20 OAG38936.1 - 1.1e-26 94.0 0.0 2.7e-24 86.2 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAG38936.1 - 9.8e-24 83.9 0.0 1.7e-23 83.2 0.0 1.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OAG38936.1 - 1.2e-21 78.4 0.0 1.4e-21 78.1 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 OAG38936.1 - 1.7e-10 41.4 0.0 1.9e-10 41.2 0.0 1.1 1 0 0 1 1 1 1 Thioesterase domain Ser_hydrolase PF06821.13 OAG38936.1 - 1.5e-08 34.7 0.0 0.00014 21.7 0.0 2.1 2 0 0 2 2 2 2 Serine hydrolase Esterase PF00756.20 OAG38936.1 - 5.5e-07 29.5 0.0 8.2e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.16 OAG38936.1 - 5e-06 26.5 0.1 0.013 15.3 0.0 3.0 1 1 2 3 3 3 1 Phospholipase/Carboxylesterase DLH PF01738.18 OAG38936.1 - 8.7e-06 25.4 0.0 0.0033 17.0 0.0 2.5 1 1 1 3 3 3 1 Dienelactone hydrolase family PGAP1 PF07819.13 OAG38936.1 - 1.2e-05 25.2 0.1 0.0021 17.8 0.0 2.2 1 1 1 2 2 2 1 PGAP1-like protein DUF915 PF06028.11 OAG38936.1 - 8.8e-05 21.9 0.0 0.18 11.1 0.0 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase of unknown function (DUF915) BAAT_C PF08840.11 OAG38936.1 - 0.00012 22.1 0.0 0.00064 19.7 0.0 1.9 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Palm_thioest PF02089.15 OAG38936.1 - 0.00043 20.2 0.0 0.00052 19.9 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_5 PF12695.7 OAG38936.1 - 0.00063 19.5 0.0 0.023 14.5 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family LIDHydrolase PF10230.9 OAG38936.1 - 0.0069 16.0 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Ndr PF03096.14 OAG38936.1 - 0.012 14.3 0.0 0.016 13.9 0.0 1.2 1 0 0 1 1 1 0 Ndr family UPF0227 PF05728.12 OAG38936.1 - 0.017 15.1 0.0 0.047 13.6 0.0 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0227) Abhydrolase_3 PF07859.13 OAG38936.1 - 0.018 14.9 0.0 0.026 14.4 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Lipase_3 PF01764.25 OAG38936.1 - 0.026 14.4 0.0 0.043 13.7 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Chlorophyllase2 PF12740.7 OAG38936.1 - 0.039 12.9 0.1 0.13 11.2 0.2 2.0 2 1 0 2 2 2 0 Chlorophyllase enzyme DUF676 PF05057.14 OAG38936.1 - 0.048 13.2 0.0 0.072 12.6 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Ribosomal_L36 PF00444.18 OAG38937.1 - 1.6e-20 73.0 7.8 2.2e-20 72.5 7.8 1.2 1 0 0 1 1 1 1 Ribosomal protein L36 NMT_C PF02799.15 OAG38938.1 - 1e-82 276.8 0.0 1.5e-82 276.2 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 OAG38938.1 - 5.1e-70 234.4 0.1 5.3e-69 231.1 0.0 2.1 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_9 PF13527.7 OAG38938.1 - 0.00023 21.3 0.1 0.0093 16.0 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAG38938.1 - 0.15 12.3 0.0 0.3 11.3 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family F-box-like PF12937.7 OAG38939.1 - 2.2e-05 24.2 0.1 9.3e-05 22.2 0.0 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 OAG38939.1 - 0.0018 18.1 0.0 0.0043 16.9 0.0 1.6 1 0 0 1 1 1 1 F-box domain XPG_N PF00752.17 OAG38940.1 - 3e-35 120.7 0.0 8e-35 119.4 0.0 1.8 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 OAG38940.1 - 1.3e-24 86.3 0.1 4.1e-24 84.8 0.0 2.0 2 0 0 2 2 2 1 XPG I-region 5_3_exonuc PF01367.20 OAG38940.1 - 0.0003 21.3 0.0 0.00093 19.8 0.0 1.8 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold UIM PF02809.20 OAG38940.1 - 0.00039 20.1 3.0 0.00039 20.1 3.0 3.6 3 0 0 3 3 3 1 Ubiquitin interaction motif HHH_5 PF14520.6 OAG38940.1 - 0.088 13.4 0.0 0.27 11.9 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix domain HHH PF00633.23 OAG38940.1 - 4.1 7.5 5.2 0.97 9.4 0.2 2.6 3 0 0 3 3 3 0 Helix-hairpin-helix motif WD40 PF00400.32 OAG38941.1 - 9.2e-16 58.0 10.5 6.1e-05 23.7 0.1 7.0 6 1 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG38941.1 - 6.1e-12 45.7 0.0 1.1e-07 32.0 0.0 4.5 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 OAG38941.1 - 3.1e-05 23.8 3.0 0.56 10.2 0.1 4.5 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat HIRA_B PF09453.10 OAG38941.1 - 0.00031 20.5 0.2 0.00088 19.1 0.2 1.8 1 0 0 1 1 1 1 HIRA B motif eIF2A PF08662.11 OAG38941.1 - 0.00073 19.5 0.2 0.086 12.7 0.0 3.0 2 1 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 OAG38941.1 - 0.018 14.4 0.0 0.033 13.5 0.0 1.4 1 0 0 1 1 1 0 WD40-like domain PSII_BNR PF14870.6 OAG38941.1 - 0.052 12.8 0.0 0.094 12.0 0.0 1.3 1 0 0 1 1 1 0 Photosynthesis system II assembly factor YCF48 Metallophos PF00149.28 OAG38942.1 - 1.2e-35 123.9 0.2 1.7e-35 123.4 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 OAG38942.1 - 3.7e-16 59.3 0.0 6.9e-16 58.4 0.0 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain LSM PF01423.22 OAG38943.1 - 9.6e-10 38.0 0.0 1.3e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 OAG38943.1 - 2.1e-06 27.8 0.1 6.4e-06 26.2 0.1 1.7 1 1 0 1 1 1 1 Ataxin 2 SM domain Sox_N PF12444.8 OAG38944.1 - 3.7 8.8 9.5 2 9.6 6.0 2.1 2 0 0 2 2 2 0 Sox developmental protein N terminal N-SET PF11764.8 OAG38945.1 - 2.5e-44 151.4 0.1 2.5e-44 151.4 0.1 2.5 3 0 0 3 3 3 1 COMPASS (Complex proteins associated with Set1p) component N SET_assoc PF11767.8 OAG38945.1 - 6.1e-24 83.5 0.5 1.2e-23 82.5 0.5 1.5 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated SET PF00856.28 OAG38945.1 - 9.5e-21 74.9 0.1 9.5e-21 74.9 0.1 3.1 2 1 0 2 2 2 1 SET domain RRM_1 PF00076.22 OAG38945.1 - 0.00023 20.9 0.1 0.00068 19.4 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Trm112p PF03966.16 OAG38946.1 - 5.5e-15 55.7 0.0 1.2e-14 54.6 0.0 1.6 1 1 0 1 1 1 1 Trm112p-like protein DEK_C PF08766.11 OAG38947.1 - 0.2 11.6 0.0 0.46 10.4 0.0 1.6 1 0 0 1 1 1 0 DEK C terminal domain Gpr1_Fun34_YaaH PF01184.19 OAG38948.1 - 3.3e-90 301.2 17.9 3.9e-90 301.0 17.9 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Memo PF01875.17 OAG38949.1 - 9.5e-63 211.9 0.0 1.1e-62 211.6 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein zf-RING_2 PF13639.6 OAG38951.1 - 0.0005 20.3 8.4 0.0011 19.2 8.4 1.6 1 0 0 1 1 1 1 Ring finger domain Rad50_zn_hook PF04423.14 OAG38951.1 - 0.017 14.9 0.1 0.047 13.5 0.1 1.7 1 0 0 1 1 1 0 Rad50 zinc hook motif zf-ANAPC11 PF12861.7 OAG38951.1 - 0.022 14.8 3.1 0.038 14.0 3.1 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF2256 PF10013.9 OAG38951.1 - 0.026 14.7 2.1 4.9 7.3 0.2 2.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) Prok-RING_1 PF14446.6 OAG38951.1 - 0.035 14.0 8.3 0.05 13.5 6.5 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 FANCL_C PF11793.8 OAG38951.1 - 0.19 11.9 6.9 0.37 11.0 6.9 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain zf-rbx1 PF12678.7 OAG38951.1 - 0.24 11.7 7.2 0.63 10.4 7.2 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-HC2 PF13490.6 OAG38951.1 - 1.3 9.3 6.9 0.37 11.1 1.0 2.8 3 0 0 3 3 3 0 Putative zinc-finger zf-C3HC4_3 PF13920.6 OAG38951.1 - 1.9 8.4 9.0 8.1 6.4 9.3 1.8 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Cyt-b5 PF00173.28 OAG38952.1 - 9.2e-17 61.0 0.0 1.5e-16 60.3 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FKBP_C PF00254.28 OAG38953.1 - 9.4e-32 109.2 0.0 1.1e-31 108.9 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase EssA PF10661.9 OAG38954.1 - 0.043 13.7 0.1 0.063 13.1 0.1 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA MAGI_u5 PF16666.5 OAG38955.1 - 2.1 8.5 10.3 1.5 9.0 8.8 1.5 2 0 0 2 2 2 0 Unstructured region on MAGI UvrD_C PF13361.6 OAG38956.1 - 2.7e-60 204.6 0.2 1.6e-58 198.8 0.0 2.4 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.21 OAG38956.1 - 1.4e-59 202.2 1.9 1.1e-57 196.0 0.0 3.6 3 1 0 3 3 3 1 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 OAG38956.1 - 2.8e-32 112.1 0.0 2.8e-31 108.8 0.0 2.7 3 0 0 3 3 3 1 AAA domain UvrD_C_2 PF13538.6 OAG38956.1 - 1.2e-13 50.7 0.7 2.8e-13 49.5 0.0 2.0 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 OAG38956.1 - 1.3e-09 38.0 0.2 6.1e-05 22.8 0.0 3.2 3 0 0 3 3 3 2 AAA domain Viral_helicase1 PF01443.18 OAG38956.1 - 4.9e-07 29.7 0.4 0.012 15.3 0.1 3.1 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_12 PF13087.6 OAG38956.1 - 6e-05 22.8 0.1 0.0019 17.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 OAG38956.1 - 0.00072 19.4 0.5 0.003 17.4 0.0 2.3 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 OAG38956.1 - 0.0093 16.2 0.2 3.3 8.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain TetR_C_35 PF18556.1 OAG38956.1 - 0.14 12.3 0.0 0.47 10.6 0.0 1.9 1 0 0 1 1 1 0 Bacterial Tetracyclin repressor, C-terminal domain FAD_binding_3 PF01494.19 OAG38958.1 - 1.8e-16 60.4 0.2 4.3e-09 36.1 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 OAG38958.1 - 1.2e-08 34.5 2.4 0.0013 18.0 1.7 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAG38958.1 - 7.4e-08 32.4 8.9 0.0046 16.6 0.0 2.4 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAG38958.1 - 7.6e-07 29.3 1.8 2.3e-06 27.7 1.8 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 OAG38958.1 - 0.00011 22.7 0.8 0.028 15.0 0.4 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAG38958.1 - 0.0004 20.4 0.4 0.00091 19.2 0.0 1.8 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 OAG38958.1 - 0.00095 18.4 6.2 0.0018 17.5 5.3 1.8 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 OAG38958.1 - 0.001 17.8 4.2 0.063 12.0 3.3 2.1 2 0 0 2 2 2 1 HI0933-like protein Trp_halogenase PF04820.14 OAG38958.1 - 0.0012 17.8 2.8 0.33 9.7 2.8 2.3 2 0 0 2 2 2 2 Tryptophan halogenase GIDA PF01134.22 OAG38958.1 - 0.002 17.3 5.4 0.015 14.4 5.9 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A Amino_oxidase PF01593.24 OAG38958.1 - 0.002 17.5 0.2 1.8 7.8 0.2 2.4 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 OAG38958.1 - 0.0023 17.1 2.2 0.14 11.2 0.0 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 OAG38958.1 - 0.0026 17.1 3.1 0.22 10.7 5.4 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAG38958.1 - 0.0059 15.9 1.9 0.011 15.0 1.9 1.3 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 OAG38958.1 - 0.0097 15.3 5.9 0.021 14.2 5.9 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase SE PF08491.10 OAG38958.1 - 0.068 12.2 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Squalene epoxidase 3HCDH_N PF02737.18 OAG38958.1 - 0.33 10.8 1.4 0.58 10.0 1.4 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 OAG38958.1 - 0.45 9.8 2.2 0.91 8.8 2.2 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Glyco_hydro_36C PF16874.5 OAG38959.1 - 0.0021 18.5 0.1 0.81 10.2 0.0 2.5 3 0 0 3 3 3 2 Glycosyl hydrolase family 36 C-terminal domain IBR PF01485.21 OAG38960.1 - 3.3e-14 52.8 36.3 2.6e-09 37.1 3.8 3.6 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain zf-CCCH PF00642.24 OAG38960.1 - 3.4e-11 42.8 12.6 2.4e-05 24.1 2.6 2.8 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 OAG38960.1 - 5.3e-11 42.2 19.0 2.1e-05 24.4 5.6 2.9 2 0 0 2 2 2 2 Zinc finger domain Torus PF16131.5 OAG38960.1 - 1.6e-10 41.6 5.0 0.00029 21.5 0.3 2.9 1 1 1 2 2 2 2 Torus domain zf-CCCH_4 PF18044.1 OAG38960.1 - 7.9e-09 35.1 16.3 0.00012 21.8 4.4 2.9 2 0 0 2 2 2 2 CCCH-type zinc finger zf-C3HC4_4 PF15227.6 OAG38960.1 - 2e-05 24.6 12.2 2e-05 24.6 12.2 4.1 4 1 0 4 4 4 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 OAG38960.1 - 0.0064 16.5 14.4 0.0064 16.5 14.4 3.7 3 1 0 3 3 3 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 OAG38960.1 - 0.0092 15.8 10.5 0.0092 15.8 10.5 4.5 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH_2 PF14608.6 OAG38960.1 - 0.28 11.7 22.9 0.075 13.5 4.5 3.6 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger Cyclin_N PF00134.23 OAG38961.1 - 3.1e-38 130.4 0.7 2.6e-36 124.2 0.2 2.2 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 OAG38961.1 - 1.1e-07 32.0 0.2 2.9e-07 30.6 0.2 1.8 1 1 0 1 1 1 1 Cyclin, C-terminal domain Sugar_tr PF00083.24 OAG38963.1 - 5.7e-92 308.9 21.4 7e-92 308.6 21.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG38963.1 - 4.5e-28 98.2 50.8 4.3e-22 78.5 28.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 OAG38963.1 - 0.0032 15.8 4.8 0.006 14.9 1.1 2.3 2 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family Phage_holin_3_2 PF04550.12 OAG38963.1 - 1.7 9.2 8.6 0.25 11.9 3.4 2.3 2 0 0 2 2 2 0 Phage holin family 2 FAD_oxidored PF12831.7 OAG38965.1 - 3.4e-90 303.5 0.0 4.5e-90 303.1 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAG38965.1 - 3.3e-08 33.7 0.3 3.1e-07 30.5 0.2 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAG38965.1 - 2.6e-05 24.0 0.0 6.8e-05 22.6 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OAG38965.1 - 4.3e-05 22.8 0.3 8.6e-05 21.8 0.3 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 OAG38965.1 - 0.00011 21.6 0.0 0.00019 20.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OAG38965.1 - 0.0089 15.2 0.3 0.014 14.5 0.3 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.17 OAG38965.1 - 0.075 12.3 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 OAG38965.1 - 0.14 10.8 0.2 0.21 10.3 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein Fungal_trans PF04082.18 OAG38966.1 - 6.1e-19 68.1 0.3 9e-19 67.5 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.18 OAG38967.1 - 1.9e-20 73.0 1.4 9.3e-15 54.4 0.4 3.0 1 1 1 2 2 2 2 Fungal specific transcription factor domain PQ-loop PF04193.14 OAG38968.1 - 1.1e-24 85.9 7.0 1.4e-15 56.8 1.4 2.5 2 0 0 2 2 2 2 PQ loop repeat tRNA-synt_2 PF00152.20 OAG38969.1 - 1.1e-87 294.1 0.0 1.5e-87 293.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) Aminotran_1_2 PF00155.21 OAG38969.1 - 2.5e-17 63.1 0.0 3.9e-17 62.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 OAG38969.1 - 1.3e-07 30.5 0.0 2e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 OAG38969.1 - 8.1e-06 25.0 0.0 1.3e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 OAG38969.1 - 9.2e-05 21.8 0.0 0.00034 20.0 0.0 1.7 2 0 0 2 2 2 1 Beta-eliminating lyase ABC2_membrane PF01061.24 OAG38970.1 - 2.1e-34 118.8 20.5 4.3e-34 117.8 20.5 1.5 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 OAG38970.1 - 2.5e-26 92.8 0.1 4.6e-26 92.0 0.1 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 OAG38970.1 - 5.6e-06 25.7 24.4 5.6e-06 25.7 24.4 2.1 1 1 1 2 2 2 1 ABC-2 family transporter protein AAA_21 PF13304.6 OAG38970.1 - 3.7e-05 23.7 0.0 0.29 10.9 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 OAG38970.1 - 0.0012 18.6 0.0 0.0023 17.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 OAG38970.1 - 0.0049 16.8 0.3 0.011 15.6 0.1 1.7 2 0 0 2 2 2 1 RsgA GTPase SMC_N PF02463.19 OAG38970.1 - 0.042 13.3 0.0 0.18 11.2 0.0 1.9 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 OAG38970.1 - 0.06 13.8 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 OAG38970.1 - 0.11 12.8 0.0 0.23 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 OAG38970.1 - 0.11 12.6 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 OAG38970.1 - 0.12 13.0 0.0 0.24 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain hEGF PF12661.7 OAG38970.1 - 0.46 11.2 14.9 0.17 12.5 3.0 4.1 3 0 0 3 3 3 0 Human growth factor-like EGF Ogr_Delta PF04606.12 OAG38970.1 - 4.6 7.3 9.3 4.7 7.3 7.0 2.3 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger MaoC_dehydratas PF01575.19 OAG38971.1 - 0.046 13.3 0.0 0.076 12.6 0.0 1.3 1 0 0 1 1 1 0 MaoC like domain zf-4CXXC_R1 PF10497.9 OAG38972.1 - 1.6e-06 28.3 14.0 1.6e-06 28.3 14.0 2.4 2 0 0 2 2 2 1 Zinc-finger domain of monoamine-oxidase A repressor R1 ZZ PF00569.17 OAG38972.1 - 9.1e-05 22.2 9.4 9.1e-05 22.2 9.4 2.9 3 0 0 3 3 3 1 Zinc finger, ZZ type JmjC PF02373.22 OAG38972.1 - 0.0024 18.3 0.0 0.0053 17.2 0.0 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase FlxA PF14282.6 OAG38972.1 - 0.13 12.3 0.1 0.23 11.4 0.1 1.3 1 0 0 1 1 1 0 FlxA-like protein Cupin_2 PF07883.11 OAG38972.1 - 0.18 11.6 0.0 0.31 10.8 0.0 1.3 1 0 0 1 1 1 0 Cupin domain AA_permease PF00324.21 OAG38973.1 - 1.9e-112 376.3 42.0 2.3e-112 376.0 42.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAG38973.1 - 9.3e-27 93.9 45.0 1.2e-26 93.6 45.0 1.1 1 0 0 1 1 1 1 Amino acid permease Smim3 PF17307.2 OAG38973.1 - 0.15 11.6 2.1 0.53 9.8 2.1 1.9 1 0 0 1 1 1 0 Small integral membrane protein 3 p450 PF00067.22 OAG38974.1 - 6.8e-59 199.8 0.0 3.6e-58 197.4 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 Importin_rep_4 PF18808.1 OAG38975.1 - 1.3e-34 118.3 4.4 6.6e-34 116.1 1.3 3.7 3 1 1 4 4 3 1 Importin repeat HEAT_EZ PF13513.6 OAG38975.1 - 4.5e-21 74.9 7.4 2e-08 34.5 0.1 8.9 9 0 0 9 9 9 2 HEAT-like repeat Importin_rep_5 PF18816.1 OAG38975.1 - 8.6e-21 74.0 3.5 3e-20 72.3 3.5 2.0 1 0 0 1 1 1 1 Importin repeat HEAT PF02985.22 OAG38975.1 - 3.4e-18 64.2 10.8 0.0044 17.2 0.0 11.8 14 0 0 14 14 11 3 HEAT repeat HEAT_2 PF13646.6 OAG38975.1 - 4.4e-18 65.5 5.0 5.4e-05 23.5 0.0 8.1 5 2 2 7 7 7 4 HEAT repeats Importin_rep_6 PF18829.1 OAG38975.1 - 5.3e-13 49.0 2.0 8.2e-12 45.2 0.1 3.2 3 0 0 3 3 3 1 Importin repeat 6 Vac14_Fab1_bd PF12755.7 OAG38975.1 - 1.6e-10 41.4 0.0 0.052 14.1 0.0 6.7 6 1 3 9 9 7 2 Vacuolar 14 Fab1-binding region DUF3385 PF11865.8 OAG38975.1 - 4.5e-09 36.4 0.8 0.051 13.5 0.0 6.8 5 3 1 6 6 6 1 Domain of unknown function (DUF3385) MMS19_C PF12460.8 OAG38975.1 - 8.7e-08 31.7 0.3 5.7e-07 29.0 0.4 2.5 1 1 1 2 2 2 1 RNAPII transcription regulator C-terminal RIX1 PF08167.12 OAG38975.1 - 3.9e-06 26.7 0.0 0.00036 20.3 0.0 3.3 2 1 1 3 3 2 1 rRNA processing/ribosome biogenesis CLASP_N PF12348.8 OAG38975.1 - 8.2e-06 25.5 0.0 0.022 14.3 0.0 4.6 4 1 1 5 5 5 1 CLASP N terminal Cnd1 PF12717.7 OAG38975.1 - 1e-05 25.7 0.0 0.14 12.2 0.0 5.1 4 3 1 5 5 4 1 non-SMC mitotic condensation complex subunit 1 Xpo1 PF08389.12 OAG38975.1 - 1.7e-05 24.9 0.5 0.13 12.3 0.0 4.5 4 0 0 4 4 4 1 Exportin 1-like protein Arm PF00514.23 OAG38975.1 - 2.9e-05 23.9 6.9 0.04 14.0 0.0 5.2 5 0 0 5 5 4 1 Armadillo/beta-catenin-like repeat DRIM PF07539.12 OAG38975.1 - 0.00012 20.6 0.3 0.04 12.2 0.2 3.6 3 1 0 4 4 4 1 Down-regulated in metastasis Adaptin_N PF01602.20 OAG38975.1 - 0.00054 18.6 0.5 0.43 9.1 0.1 3.7 3 0 0 3 3 3 1 Adaptin N terminal region RTP1_C1 PF10363.9 OAG38975.1 - 0.0033 17.6 2.4 0.17 12.1 0.3 4.5 5 1 2 7 7 6 1 Required for nuclear transport of RNA pol II C-terminus 1 IBN_N PF03810.19 OAG38975.1 - 0.01 15.8 0.1 0.13 12.2 0.0 3.2 2 0 0 2 2 1 0 Importin-beta N-terminal domain Cohesin_HEAT PF12765.7 OAG38975.1 - 0.022 15.1 0.0 1.4 9.3 0.0 3.2 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion DUF4042 PF13251.6 OAG38975.1 - 0.024 14.3 0.0 17 5.1 0.0 4.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4042) TFCD_C PF12612.8 OAG38975.1 - 0.043 13.6 0.0 16 5.3 0.0 3.1 2 0 0 2 2 2 0 Tubulin folding cofactor D C terminal Sec6 PF06046.13 OAG38975.1 - 0.065 11.6 0.5 0.18 10.2 0.5 1.7 1 0 0 1 1 1 0 Exocyst complex component Sec6 YihI PF04220.12 OAG38975.1 - 0.074 12.8 0.5 0.22 11.2 0.5 1.8 1 0 0 1 1 1 0 Der GTPase activator (YihI) MIF4G_like_2 PF09090.11 OAG38975.1 - 0.078 12.4 0.2 0.28 10.6 0.1 2.0 2 0 0 2 2 2 0 MIF4G like V-ATPase_H_N PF03224.14 OAG38975.1 - 0.13 11.5 1.3 0.82 8.9 0.1 2.8 3 0 0 3 3 3 0 V-ATPase subunit H Bromodomain PF00439.25 OAG38976.1 - 3.1e-19 68.8 0.2 7.8e-19 67.5 0.2 1.7 1 0 0 1 1 1 1 Bromodomain Bromo_TP PF07524.13 OAG38976.1 - 5.3e-05 23.1 0.0 0.00011 22.1 0.0 1.5 1 0 0 1 1 1 1 Bromodomain associated PBP1_TM PF14812.6 OAG38976.1 - 3.2 8.2 19.6 0.043 14.2 4.7 3.2 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal VanZ PF04892.12 OAG38977.1 - 6.1e-06 26.9 0.6 9e-06 26.4 0.6 1.3 1 0 0 1 1 1 1 VanZ like family Acyl_transf_3 PF01757.22 OAG38977.1 - 0.0043 16.2 0.9 0.005 16.0 0.9 1.1 1 0 0 1 1 1 1 Acyltransferase family DUF4611 PF15387.6 OAG38977.1 - 0.54 10.5 2.7 0.97 9.7 2.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) NAD_binding_6 PF08030.12 OAG38978.1 - 6.9e-32 110.7 0.0 1.6e-31 109.5 0.0 1.6 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 OAG38978.1 - 8.5e-21 74.1 0.0 1.8e-20 73.1 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 OAG38978.1 - 1.9e-18 66.8 11.1 6.5e-18 65.0 8.3 2.3 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.21 OAG38978.1 - 0.13 12.9 0.0 0.48 11.1 0.0 2.0 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain MIS13 PF08202.11 OAG38979.1 - 1.3e-42 146.2 0.0 2.4e-42 145.3 0.0 1.5 1 0 0 1 1 1 1 Mis12-Mtw1 protein family pPIWI_RE_Y PF18156.1 OAG38979.1 - 0.039 14.4 0.5 0.23 11.9 0.0 2.4 3 0 0 3 3 3 0 pPIWI_RE three-gene island domain Y FAD_binding_3 PF01494.19 OAG38980.1 - 8.2e-08 31.9 3.6 1.5e-05 24.4 0.1 3.0 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.24 OAG38980.1 - 0.0084 15.7 2.4 0.036 13.7 1.0 2.2 1 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG38980.1 - 0.087 12.0 0.3 0.59 9.3 0.2 2.3 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Cwf_Cwc_15 PF04889.12 OAG38981.1 - 0.00052 19.8 7.5 0.00052 19.8 7.5 1.9 2 0 0 2 2 2 1 Cwf15/Cwc15 cell cycle control protein TFIIF_alpha PF05793.12 OAG38981.1 - 0.0041 15.8 1.3 0.0041 15.8 1.3 2.7 3 0 0 3 3 3 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) ADH_zinc_N PF00107.26 OAG38983.1 - 6.4e-22 77.9 0.1 6.4e-22 77.9 0.1 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG38983.1 - 1.2e-17 63.7 0.6 1.2e-17 63.7 0.6 2.3 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 OAG38983.1 - 1.1e-06 28.3 0.2 2.4e-06 27.2 0.0 1.7 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 OAG38983.1 - 4e-05 24.7 0.0 9.4e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 OAG38983.1 - 0.037 14.0 0.0 0.094 12.7 0.0 1.8 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-associated TrkA_N PF02254.18 OAG38983.1 - 0.051 13.8 0.1 0.051 13.8 0.1 1.8 2 0 0 2 2 2 0 TrkA-N domain RIFIN PF02009.16 OAG38983.1 - 0.16 11.9 4.3 0.27 11.1 4.3 1.3 1 0 0 1 1 1 0 Rifin 4HBT PF03061.22 OAG38984.1 - 1.1e-07 32.1 0.0 1.6e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily LssY_C PF14067.6 OAG38984.1 - 0.099 12.2 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 LssY C-terminus DUF3659 PF12396.8 OAG38984.1 - 0.11 12.4 0.1 0.19 11.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3659) PBP PF01161.20 OAG38985.1 - 5.2e-14 52.7 0.0 6.2e-14 52.4 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein MFS_1 PF07690.16 OAG38986.1 - 4.6e-48 163.9 21.2 1.4e-45 155.8 22.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG38986.1 - 1.9e-05 23.8 22.9 0.00079 18.4 23.7 2.7 1 1 1 2 2 2 2 Sugar (and other) transporter OATP PF03137.20 OAG38986.1 - 0.056 11.7 5.8 1.3 7.2 1.2 2.7 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF4834 PF16118.5 OAG38986.1 - 0.085 13.8 0.0 0.58 11.2 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) OAD_gamma PF04277.13 OAG38986.1 - 0.11 13.1 1.2 2.7 8.6 0.0 2.8 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain DUF3054 PF11255.8 OAG38986.1 - 8.3 7.0 12.8 1.5 9.3 7.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3054) CH PF00307.31 OAG38988.1 - 4.8e-08 33.2 0.0 0.00094 19.3 0.0 2.6 2 0 0 2 2 2 2 Calponin homology (CH) domain IQ PF00612.27 OAG38988.1 - 0.018 14.8 4.3 0.055 13.3 4.3 1.8 1 0 0 1 1 1 0 IQ calmodulin-binding motif DUF2335 PF10097.9 OAG38988.1 - 2.2 8.3 4.8 1.5 8.8 2.2 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2335) ERO1 PF04137.15 OAG38989.1 - 1.9e-132 441.8 0.1 2.5e-132 441.4 0.1 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) PH PF00169.29 OAG38990.1 - 2e-06 28.3 0.2 4.2e-06 27.2 0.2 1.5 1 0 0 1 1 1 1 PH domain TFIIA PF03153.13 OAG38990.1 - 4.1 7.3 25.0 6.9 6.6 25.0 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit WD40 PF00400.32 OAG38991.1 - 5.2e-11 42.9 12.0 8.6e-05 23.2 0.1 4.3 5 0 0 5 5 5 3 WD domain, G-beta repeat DSHCT PF08148.12 OAG38992.1 - 1.8e-51 174.0 0.4 4.9e-51 172.7 0.4 1.8 1 0 0 1 1 1 1 DSHCT (NUC185) domain Ski2_N PF17911.1 OAG38992.1 - 1.5e-38 131.7 0.1 9.2e-38 129.1 0.1 2.1 2 0 0 2 2 2 1 Ski2 N-terminal region rRNA_proc-arch PF13234.6 OAG38992.1 - 7.8e-21 75.2 0.4 1.3e-20 74.5 0.4 1.4 1 0 0 1 1 1 1 rRNA-processing arch domain DEAD PF00270.29 OAG38992.1 - 8.8e-19 67.9 0.0 1.9e-18 66.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAG38992.1 - 1.3e-06 28.7 0.0 7.1e-06 26.3 0.0 2.4 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG38992.1 - 1.2e-05 25.4 0.0 2.6e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Lactamase_B_5 PF14597.6 OAG38993.1 - 0.06 12.8 0.0 0.086 12.3 0.0 1.2 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily DUF1533 PF07550.11 OAG38993.1 - 0.085 12.8 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1533) Ribosomal_S8e PF01201.22 OAG38994.1 - 2.5e-46 157.3 0.2 4.4e-46 156.5 0.2 1.4 1 1 0 1 1 1 1 Ribosomal protein S8e PilO PF04350.13 OAG38994.1 - 0.18 11.9 1.8 0.3 11.3 1.8 1.3 1 0 0 1 1 1 0 Pilus assembly protein, PilO Pannexin_like PF12534.8 OAG38994.1 - 1.2 8.2 4.8 1.7 7.7 4.8 1.1 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 Mo-co_dimer PF03404.16 OAG38995.1 - 1.1e-59 200.4 0.0 2e-59 199.5 0.0 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Oxidored_molyb PF00174.19 OAG38995.1 - 8.7e-55 185.0 0.0 1.5e-54 184.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain FAD_binding_6 PF00970.24 OAG38995.1 - 5e-32 110.2 0.0 8.7e-32 109.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 OAG38995.1 - 9.5e-29 100.2 0.0 2.3e-28 99.0 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.28 OAG38995.1 - 4e-20 71.7 0.0 8.1e-20 70.7 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 OAG38995.1 - 0.00083 19.5 0.0 0.034 14.3 0.0 2.5 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Pyr_redox_2 PF07992.14 OAG38996.1 - 3.3e-48 164.4 0.6 4.8e-48 163.9 0.6 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NIR_SIR PF01077.22 OAG38996.1 - 4.3e-20 71.8 0.0 7.6e-20 71.0 0.0 1.4 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Pyr_redox PF00070.27 OAG38996.1 - 5.7e-16 58.8 6.4 5.5e-15 55.7 0.8 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Fer2_BFD PF04324.15 OAG38996.1 - 6.4e-15 55.2 3.3 3e-11 43.5 3.7 2.6 2 0 0 2 2 2 2 BFD-like [2Fe-2S] binding domain Rieske PF00355.26 OAG38996.1 - 5.5e-12 45.5 0.5 3.9e-11 42.7 0.0 2.6 3 0 0 3 3 3 1 Rieske [2Fe-2S] domain NIR_SIR_ferr PF03460.17 OAG38996.1 - 1.4e-09 37.7 0.0 4.2e-09 36.1 0.0 1.9 2 0 0 2 2 2 1 Nitrite/Sulfite reductase ferredoxin-like half domain Rieske_2 PF13806.6 OAG38996.1 - 4.1e-08 33.1 0.0 1.5e-07 31.3 0.0 2.1 2 0 0 2 2 1 1 Rieske-like [2Fe-2S] domain Rubredoxin_C PF18267.1 OAG38996.1 - 0.0001 22.2 0.1 1 9.3 0.0 3.7 3 0 0 3 3 3 2 Rubredoxin NAD+ reductase C-terminal domain NAD_binding_9 PF13454.6 OAG38996.1 - 0.00023 21.2 0.4 2.4 8.1 0.0 3.4 2 1 1 3 3 3 2 FAD-NAD(P)-binding NAD_binding_7 PF13241.6 OAG38996.1 - 0.07 13.6 0.2 2.9 8.4 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding AlaDh_PNT_C PF01262.21 OAG38996.1 - 0.093 12.0 1.4 2.9 7.1 0.2 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain K_oxygenase PF13434.6 OAG38996.1 - 0.094 11.8 0.0 0.99 8.5 0.0 2.0 1 1 1 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.22 OAG38996.1 - 0.26 10.3 1.3 47 2.9 0.0 3.0 2 1 1 3 3 3 0 Glucose inhibited division protein A TrkA_N PF02254.18 OAG38996.1 - 0.26 11.5 0.7 19 5.6 0.1 2.5 2 0 0 2 2 2 0 TrkA-N domain FAD_binding_2 PF00890.24 OAG38996.1 - 0.64 9.0 2.5 7.9 5.4 0.0 2.6 1 1 2 3 3 3 0 FAD binding domain Vps62 PF06101.11 OAG38997.1 - 3.5e-12 45.4 0.2 5.6e-11 41.4 0.0 2.2 2 0 0 2 2 2 1 Vacuolar protein sorting-associated protein 62 S1FA PF04689.13 OAG38997.1 - 0.048 13.8 0.1 0.048 13.8 0.1 2.0 2 0 0 2 2 2 0 DNA binding protein S1FA TMIE PF16038.5 OAG38997.1 - 0.076 12.9 0.2 0.12 12.2 0.2 1.3 1 0 0 1 1 1 0 TMIE protein Comm PF15957.5 OAG38997.1 - 0.15 12.4 0.0 0.44 10.9 0.0 1.7 2 0 0 2 2 2 0 Commissureless tRNA-synt_2 PF00152.20 OAG39000.1 - 1e-66 225.2 0.0 1.2e-64 218.4 0.0 2.2 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.9 OAG39000.1 - 3.7e-20 72.1 0.2 5.4e-20 71.6 0.2 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2156) tRNA_anti-codon PF01336.25 OAG39000.1 - 3.6e-06 26.9 0.6 7e-06 26.0 0.6 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DUF4853 PF16145.5 OAG39000.1 - 0.1 12.7 0.2 0.43 10.7 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4853) NACHT_N PF17100.5 OAG39001.1 - 3.3e-60 203.7 0.1 6.1e-60 202.8 0.1 1.5 1 0 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase Ank_2 PF12796.7 OAG39001.1 - 1.8e-40 137.4 2.4 1.1e-12 48.3 0.0 8.9 6 3 2 9 9 9 8 Ankyrin repeats (3 copies) Ank PF00023.30 OAG39001.1 - 1.4e-37 126.5 8.8 2e-06 28.0 0.0 13.7 13 1 0 13 13 13 7 Ankyrin repeat Ank_4 PF13637.6 OAG39001.1 - 1e-36 124.8 13.8 2.2e-09 37.6 0.1 12.7 8 3 3 12 12 12 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 OAG39001.1 - 9.3e-34 115.1 12.6 2.7e-11 43.5 0.3 10.0 10 0 0 10 10 10 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG39001.1 - 9.2e-25 84.0 5.9 6.6e-05 23.0 0.0 13.5 14 0 0 14 14 14 3 Ankyrin repeat NACHT PF05729.12 OAG39001.1 - 0.0001 22.3 0.3 0.00035 20.5 0.0 2.0 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 OAG39001.1 - 0.0038 17.6 2.0 0.0073 16.7 0.0 2.5 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 OAG39001.1 - 0.015 15.5 0.0 0.069 13.4 0.0 2.1 1 0 0 1 1 1 0 AAA domain FdhE PF04216.12 OAG39001.1 - 0.88 9.4 9.1 1.2 8.9 0.2 3.9 4 0 0 4 4 4 0 Protein involved in formate dehydrogenase formation Pkinase PF00069.25 OAG39002.1 - 3e-36 125.2 0.0 5.3e-36 124.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG39002.1 - 4.1e-22 78.7 0.0 6e-22 78.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAG39002.1 - 0.022 13.6 0.0 0.038 12.8 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase UBA_5 PF16577.5 OAG39002.1 - 0.13 12.4 0.0 0.34 11.1 0.0 1.7 1 0 0 1 1 1 0 UBA domain SH3BGR PF04908.15 OAG39005.1 - 0.0013 18.8 0.4 0.013 15.7 0.0 2.8 3 0 0 3 3 3 1 SH3-binding, glutamic acid-rich protein GMC_oxred_N PF00732.19 OAG39006.1 - 1.1e-48 166.1 0.0 1.4e-48 165.8 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAG39006.1 - 1.4e-36 126.2 0.0 2.2e-36 125.6 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 OAG39006.1 - 5.4e-06 25.7 0.0 0.046 12.8 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 OAG39006.1 - 7.9e-05 22.8 0.1 0.00051 20.2 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 OAG39006.1 - 9e-05 21.7 0.0 0.00015 20.9 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 OAG39006.1 - 0.00022 20.9 0.1 0.011 15.4 0.0 2.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 OAG39006.1 - 0.003 16.8 0.0 0.31 10.2 0.0 2.4 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.14 OAG39006.1 - 0.0051 16.1 0.0 0.017 14.4 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAG39006.1 - 0.009 16.5 0.2 1.4 9.5 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 OAG39006.1 - 0.032 13.1 0.0 0.048 12.5 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Aldedh PF00171.22 OAG39007.1 - 5.8e-156 519.6 0.0 7e-156 519.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Glucosamine_iso PF01182.20 OAG39008.1 - 1.5e-21 77.4 0.0 2.3e-21 76.7 0.0 1.3 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Glyco_hydro_3 PF00933.21 OAG39009.1 - 2.3e-69 234.2 0.0 3.7e-69 233.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Acetyltransf_1 PF00583.25 OAG39009.1 - 7.7e-06 26.1 0.0 2.1e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_6 PF13480.7 OAG39009.1 - 0.0039 17.4 0.1 0.21 11.7 0.0 3.3 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OAG39009.1 - 0.012 15.6 0.0 0.035 14.0 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Glyco_hydro_3_C PF01915.22 OAG39009.1 - 0.024 14.6 0.0 0.046 13.7 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain Acetyltransf_7 PF13508.7 OAG39009.1 - 0.058 13.8 0.0 0.2 12.1 0.0 2.0 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain NDT80_PhoG PF05224.12 OAG39010.1 - 5.5e-38 131.1 0.0 8.3e-38 130.5 0.0 1.3 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family cobW PF02492.19 OAG39012.1 - 1.2e-48 165.1 5.8 5e-36 123.9 1.0 2.3 1 1 1 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 OAG39012.1 - 1.1e-20 73.4 0.0 6.1e-15 54.9 0.0 2.7 2 0 0 2 2 2 2 Cobalamin synthesis protein cobW C-terminal domain AAA_16 PF13191.6 OAG39012.1 - 0.00061 20.2 0.8 0.011 16.1 0.1 2.7 2 1 0 2 2 2 1 AAA ATPase domain Viral_helicase1 PF01443.18 OAG39012.1 - 0.002 17.9 0.0 0.0038 17.0 0.0 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase CPSF100_C PF13299.6 OAG39012.1 - 0.017 15.3 0.0 0.044 14.0 0.0 1.6 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal AAA_22 PF13401.6 OAG39012.1 - 0.023 15.0 0.0 0.069 13.4 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 OAG39012.1 - 0.026 15.0 0.6 0.24 11.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 OAG39012.1 - 0.031 13.3 0.0 0.063 12.3 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF4637 PF15470.6 OAG39012.1 - 0.046 13.5 4.4 0.088 12.5 4.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) AAA_33 PF13671.6 OAG39012.1 - 0.054 13.6 0.0 0.13 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain MobB PF03205.14 OAG39012.1 - 0.078 12.9 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Nop14 PF04147.12 OAG39012.1 - 0.079 11.2 8.5 0.11 10.7 8.5 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 OAG39012.1 - 0.19 10.0 6.4 0.27 9.5 6.4 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 OAG39012.1 - 7.8 5.8 13.7 12 5.2 13.7 1.2 1 0 0 1 1 1 0 SDA1 APH PF01636.23 OAG39013.1 - 9.9e-10 38.7 0.0 1.9e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family APH PF01636.23 OAG39016.1 - 4.6e-06 26.7 0.3 6.2e-06 26.3 0.3 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 OAG39016.1 - 0.12 11.7 0.0 0.15 11.4 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain zf-C2H2_4 PF13894.6 OAG39017.1 - 2.3e-12 46.6 23.4 0.022 15.5 0.0 7.6 7 0 0 7 7 7 4 C2H2-type zinc finger zf-C2H2 PF00096.26 OAG39017.1 - 0.00015 22.1 21.4 0.83 10.2 0.1 6.7 7 0 0 7 7 7 3 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 OAG39017.1 - 0.00069 19.9 26.7 0.58 10.5 5.2 5.7 3 2 3 7 7 7 4 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 OAG39017.1 - 0.023 15.0 1.1 0.023 15.0 1.1 6.8 7 0 0 7 7 7 0 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 OAG39017.1 - 0.13 12.2 0.4 0.13 12.2 0.4 4.4 5 0 0 5 5 5 0 zinc-finger of a C2HC-type Zn_ribbon_SprT PF17283.2 OAG39017.1 - 0.63 10.0 0.1 0.63 10.0 0.1 5.0 4 2 0 4 4 4 0 SprT-like zinc ribbon domain zinc_ribbon_10 PF10058.9 OAG39017.1 - 0.9 9.3 18.6 0.37 10.6 0.4 4.6 4 0 0 4 4 4 0 Predicted integral membrane zinc-ribbon metal-binding protein zf-met PF12874.7 OAG39017.1 - 5.8 7.4 23.8 10 6.7 0.0 6.5 7 0 0 7 7 7 0 Zinc-finger of C2H2 type zf-ribbon_3 PF13248.6 OAG39017.1 - 8 6.0 17.1 36 4.0 0.3 6.1 6 0 0 6 6 6 0 zinc-ribbon domain Ribul_P_3_epim PF00834.19 OAG39020.1 - 3.1e-62 209.5 0.0 4.3e-61 205.8 0.0 2.0 1 1 0 1 1 1 1 Ribulose-phosphate 3 epimerase family OMPdecase PF00215.24 OAG39020.1 - 0.034 13.7 0.0 0.044 13.4 0.0 1.3 1 0 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family QRPTase_C PF01729.19 OAG39020.1 - 0.051 13.4 0.0 0.089 12.6 0.0 1.4 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain ThiG PF05690.14 OAG39020.1 - 0.063 12.6 0.1 0.1 11.9 0.1 1.3 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG Melibiase PF02065.18 OAG39020.1 - 0.22 10.5 0.0 13 4.7 0.0 2.1 1 1 0 2 2 2 0 Melibiase EHN PF06441.12 OAG39021.1 - 9.6e-35 119.2 2.4 7.8e-34 116.3 0.1 2.4 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 OAG39021.1 - 2e-10 40.8 0.0 3.4e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG39021.1 - 3 8.4 9.4 1.3 9.6 4.8 2.4 2 1 0 2 2 2 0 Alpha/beta hydrolase family Acyltransferase PF01553.21 OAG39024.1 - 7.3e-28 96.9 0.0 1.4e-27 96.0 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 OAG39024.1 - 1e-11 44.7 0.0 2.3e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase C-terminus DENN PF02141.21 OAG39026.1 - 6.1e-54 182.8 0.1 1.2e-53 181.9 0.1 1.5 1 0 0 1 1 1 1 DENN (AEX-3) domain dDENN PF03455.19 OAG39026.1 - 7.4e-11 41.9 0.1 1.7e-10 40.7 0.1 1.7 1 0 0 1 1 1 1 dDENN domain uDENN PF03456.18 OAG39026.1 - 1.6e-08 35.1 0.1 4.5e-08 33.7 0.1 1.8 1 0 0 1 1 1 1 uDENN domain DUF974 PF06159.13 OAG39027.1 - 6.1e-79 265.3 0.0 7e-79 265.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF974) Arylsulfotran_2 PF14269.6 OAG39029.1 - 6e-74 249.1 4.7 8e-74 248.7 4.7 1.1 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 OAG39029.1 - 3.3e-18 65.7 0.6 4.4e-17 62.0 0.6 2.1 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) PQQ PF01011.21 OAG39029.1 - 0.8 9.7 6.6 1.5 8.9 0.1 3.7 4 0 0 4 4 4 0 PQQ enzyme repeat MFS_1 PF07690.16 OAG39030.1 - 1.5e-44 152.4 34.4 1.2e-43 149.4 34.3 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily UPF0227 PF05728.12 OAG39030.1 - 0.16 11.9 0.1 0.3 11.0 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Ank_2 PF12796.7 OAG39031.1 - 4.5e-52 174.6 0.6 2.3e-14 53.8 0.0 5.1 1 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAG39031.1 - 4.4e-50 167.4 0.0 4.2e-08 33.6 0.0 8.0 3 1 5 8 8 8 8 Ankyrin repeats (many copies) Ank PF00023.30 OAG39031.1 - 2.1e-41 138.6 4.3 0.0053 17.2 0.0 11.6 11 0 0 11 11 11 9 Ankyrin repeat Ank_3 PF13606.6 OAG39031.1 - 6.9e-33 109.0 0.1 0.0085 16.5 0.0 11.7 11 0 0 11 11 11 7 Ankyrin repeat Ank_5 PF13857.6 OAG39031.1 - 5.8e-22 77.5 5.2 0.00018 21.8 0.1 9.0 1 1 10 11 11 11 9 Ankyrin repeats (many copies) NACHT PF05729.12 OAG39031.1 - 2.9e-09 37.1 0.0 5.2e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 OAG39031.1 - 2.8e-07 31.1 0.0 9.5e-07 29.3 0.0 1.9 2 0 0 2 2 1 1 AAA ATPase domain DUF676 PF05057.14 OAG39031.1 - 7.2e-05 22.4 0.0 0.00015 21.3 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) ABC_tran PF00005.27 OAG39031.1 - 0.00028 21.4 0.0 0.00071 20.1 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_22 PF13401.6 OAG39031.1 - 0.0017 18.6 0.0 0.0047 17.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain PGAP1 PF07819.13 OAG39031.1 - 0.0028 17.4 0.0 0.0063 16.3 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein AAA_29 PF13555.6 OAG39031.1 - 0.0054 16.5 0.1 0.012 15.4 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Abhydrolase_6 PF12697.7 OAG39031.1 - 0.0067 17.1 2.1 0.039 14.5 0.0 3.1 3 1 1 4 4 3 1 Alpha/beta hydrolase family KAP_NTPase PF07693.14 OAG39031.1 - 0.0081 15.4 0.0 3.8 6.7 0.0 2.2 2 0 0 2 2 2 2 KAP family P-loop domain Hydrolase_4 PF12146.8 OAG39031.1 - 0.017 14.4 0.0 0.045 13.0 0.0 1.7 2 0 0 2 2 2 0 Serine aminopeptidase, S33 NTPase_1 PF03266.15 OAG39031.1 - 0.024 14.5 0.0 0.05 13.5 0.0 1.5 1 0 0 1 1 1 0 NTPase RNA_helicase PF00910.22 OAG39031.1 - 0.035 14.5 0.0 0.081 13.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Ploopntkinase3 PF18751.1 OAG39031.1 - 0.074 13.0 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 HicA_toxin PF07927.12 OAG39031.1 - 0.076 13.1 7.6 1.4e+02 2.7 0.0 6.5 7 0 0 7 7 6 0 HicA toxin of bacterial toxin-antitoxin, MMR_HSR1 PF01926.23 OAG39031.1 - 0.095 12.8 0.0 0.29 11.2 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_23 PF13476.6 OAG39031.1 - 0.11 13.0 0.0 0.23 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Biotin_lipoyl_2 PF13533.6 OAG39031.1 - 0.12 12.2 6.0 85 3.1 0.0 5.8 6 0 0 6 6 6 0 Biotin-lipoyl like AAA_18 PF13238.6 OAG39031.1 - 0.17 12.4 0.2 0.81 10.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain MFS_1 PF07690.16 OAG39034.1 - 1.9e-24 86.3 15.5 3e-24 85.6 15.5 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 OAG39034.1 - 2.5 7.8 7.1 0.18 11.5 0.4 2.5 3 1 1 4 4 4 0 Ion channel regulatory protein UNC-93 DUF308 PF03729.13 OAG39034.1 - 8.8 6.7 12.6 0.62 10.4 6.1 2.5 2 0 0 2 2 2 0 Short repeat of unknown function (DUF308) HET PF06985.11 OAG39035.1 - 6.8e-32 110.8 0.8 6.8e-32 110.8 0.8 2.4 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Fungal_trans PF04082.18 OAG39036.1 - 3.6e-16 59.0 4.5 5.3e-16 58.5 4.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain APH PF01636.23 OAG39037.1 - 5.1e-21 75.7 0.0 9.1e-21 74.9 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 OAG39037.1 - 0.00021 20.7 0.0 0.00033 20.1 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.20 OAG39037.1 - 0.032 13.8 0.0 0.83 9.2 0.0 2.1 2 0 0 2 2 2 0 Choline/ethanolamine kinase DASH_Dad2 PF08654.10 OAG39040.1 - 2.6e-28 98.4 0.0 3.9e-28 97.8 0.0 1.3 1 0 0 1 1 1 1 DASH complex subunit Dad2 IFT20 PF14931.6 OAG39040.1 - 0.21 11.8 2.9 0.97 9.6 2.9 1.8 1 1 1 2 2 2 0 Intraflagellar transport complex B, subunit 20 Shugoshin_N PF07558.11 OAG39041.1 - 6.4e-19 67.6 6.1 1.5e-18 66.4 6.1 1.7 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region Shugoshin_C PF07557.11 OAG39041.1 - 5.3e-09 35.7 4.3 5.3e-09 35.7 4.3 2.5 2 0 0 2 2 2 1 Shugoshin C terminus GIT_CC PF16559.5 OAG39041.1 - 0.0083 16.0 1.3 0.023 14.6 1.3 1.7 1 0 0 1 1 1 1 GIT coiled-coil Rho guanine nucleotide exchange factor ADIP PF11559.8 OAG39041.1 - 0.021 14.9 6.9 0.076 13.1 6.9 2.0 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DivIVA PF05103.13 OAG39041.1 - 0.052 13.6 3.2 0.18 11.9 3.2 1.9 1 0 0 1 1 1 0 DivIVA protein DivIC PF04977.15 OAG39041.1 - 0.48 10.2 4.4 0.76 9.6 1.6 2.7 1 1 1 2 2 2 0 Septum formation initiator ZapB PF06005.12 OAG39041.1 - 2.3 8.7 7.2 15 6.1 7.2 2.5 1 1 0 1 1 1 0 Cell division protein ZapB Med21 PF11221.8 OAG39042.1 - 1.3e-37 129.3 8.5 7.3e-37 126.8 8.5 1.8 1 1 0 1 1 1 1 Subunit 21 of Mediator complex Transketolase_N PF00456.21 OAG39043.1 - 2.2e-120 401.6 0.0 3e-120 401.2 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 OAG39043.1 - 3.5e-38 131.1 0.1 5.8e-38 130.3 0.1 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain DXP_synthase_N PF13292.6 OAG39043.1 - 1.5e-06 27.7 0.0 2.6e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Transketolase_C PF02780.20 OAG39043.1 - 2.1e-06 27.7 0.0 5.1e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain TPP_enzyme_C PF02775.21 OAG39043.1 - 0.00036 20.3 0.3 0.0014 18.4 0.3 2.0 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.20 OAG39043.1 - 0.038 12.9 0.0 0.065 12.2 0.0 1.3 1 0 0 1 1 1 0 Dehydrogenase E1 component PAAR_motif PF05488.13 OAG39043.1 - 0.41 10.9 2.5 6.1 7.1 0.1 2.5 2 0 0 2 2 2 0 PAAR motif Aldo_ket_red PF00248.21 OAG39044.1 - 9e-42 143.3 0.0 1.3e-41 142.7 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family ADH_N PF08240.12 OAG39045.1 - 3.9e-28 97.5 2.6 6.6e-28 96.8 2.6 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG39045.1 - 1.6e-12 47.5 0.0 3.4e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 OAG39045.1 - 6.3e-12 45.4 0.3 3.1e-06 26.8 0.0 2.3 1 1 1 2 2 2 2 Glucose dehydrogenase C-terminus Sugar_tr PF00083.24 OAG39047.1 - 3.7e-66 223.9 23.1 4.4e-66 223.6 23.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG39047.1 - 1.2e-17 63.9 21.6 7.9e-17 61.2 19.8 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 OAG39047.1 - 9.7e-06 24.7 11.3 0.00012 21.1 0.3 2.5 2 1 0 2 2 2 2 MFS_1 like family DUF1593 PF07632.11 OAG39048.1 - 3.3e-95 318.4 0.0 4.8e-95 317.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1593) REJ PF02010.15 OAG39048.1 - 2.6e-06 26.5 0.0 4.4e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 REJ domain Fungal_trans_2 PF11951.8 OAG39049.1 - 4.7e-14 52.0 0.4 1.3e-13 50.5 0.4 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain HECT PF00632.25 OAG39050.1 - 1.2e-82 277.9 0.0 2.3e-82 277.0 0.0 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.27 OAG39050.1 - 0.039 13.8 0.2 0.16 11.9 0.2 2.2 1 0 0 1 1 1 0 IQ calmodulin-binding motif SPX PF03105.19 OAG39051.1 - 8.7e-43 147.7 2.5 4.2e-30 105.9 0.6 2.2 1 1 1 2 2 2 2 SPX domain Na_sulph_symp PF00939.19 OAG39051.1 - 4.8e-30 105.0 42.9 6.9e-30 104.5 42.9 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region Abhydrolase_3 PF07859.13 OAG39051.1 - 2.2e-24 86.5 0.0 3.5e-24 85.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold CitMHS PF03600.16 OAG39051.1 - 3e-23 82.5 50.2 2e-17 63.4 20.4 2.9 2 1 1 3 3 3 2 Citrate transporter Say1_Mug180 PF10340.9 OAG39051.1 - 3e-15 56.0 2.3 3.2e-15 55.9 0.0 2.1 3 0 0 3 3 3 1 Steryl acetyl hydrolase RTA1 PF04479.13 OAG39052.1 - 1.7e-60 204.2 7.0 2.5e-60 203.6 7.0 1.2 1 0 0 1 1 1 1 RTA1 like protein Zn_clus PF00172.18 OAG39053.1 - 1.1e-07 31.9 7.7 1.1e-07 31.9 7.7 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 OAG39053.1 - 2.7e-07 29.8 2.2 3e-05 23.0 0.3 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain DUF1100 PF06500.11 OAG39054.1 - 0.00012 21.0 0.0 0.00034 19.5 0.0 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF1100) LIP PF03583.14 OAG39054.1 - 0.00021 20.8 0.0 0.00095 18.6 0.0 1.9 2 0 0 2 2 2 1 Secretory lipase Abhydrolase_6 PF12697.7 OAG39054.1 - 0.00021 22.0 6.0 0.00021 22.0 6.0 2.1 1 1 0 2 2 2 1 Alpha/beta hydrolase family DLH PF01738.18 OAG39054.1 - 0.0041 16.7 0.1 0.1 12.2 0.0 2.4 2 1 0 2 2 2 1 Dienelactone hydrolase family AXE1 PF05448.12 OAG39054.1 - 0.024 13.3 0.1 0.12 11.0 0.0 2.1 3 0 0 3 3 3 0 Acetyl xylan esterase (AXE1) Abhydrolase_1 PF00561.20 OAG39054.1 - 0.026 14.2 0.9 0.1 12.2 0.1 2.4 2 1 0 2 2 2 0 alpha/beta hydrolase fold BAAT_C PF08840.11 OAG39054.1 - 0.057 13.3 0.0 0.62 10.0 0.0 2.0 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Aldo_ket_red PF00248.21 OAG39056.1 - 3.8e-46 157.6 0.0 6.1e-37 127.4 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family Glu-tRNAGln PF02686.15 OAG39057.1 - 1.4e-08 34.9 0.3 3.2e-08 33.7 0.3 1.6 1 0 0 1 1 1 1 Glu-tRNAGln amidotransferase C subunit SNAP PF14938.6 OAG39058.1 - 8.8e-113 376.4 14.0 1e-112 376.2 14.0 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 OAG39058.1 - 4.7e-06 26.8 15.2 0.0081 16.4 2.8 4.1 2 2 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 OAG39058.1 - 0.0013 18.6 8.4 3.6 7.8 0.1 5.6 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 OAG39058.1 - 0.038 14.2 10.9 1.3 9.4 0.4 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 OAG39058.1 - 0.24 12.1 15.3 15 6.5 0.4 5.4 4 1 2 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 OAG39058.1 - 6.5 7.1 23.2 6.1 7.2 0.7 6.2 5 2 3 8 8 8 0 Tetratricopeptide repeat NSF PF02071.20 OAG39058.1 - 7.9 7.7 16.8 0.92 10.5 0.3 5.5 5 0 0 5 5 5 0 Aromatic-di-Alanine (AdAR) repeat PI3_PI4_kinase PF00454.27 OAG39059.1 - 2.4e-41 142.2 0.0 3.8e-41 141.6 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase EF-1_beta_acid PF10587.9 OAG39059.1 - 0.22 12.0 7.1 0.083 13.4 3.2 2.3 2 0 0 2 2 2 0 Eukaryotic elongation factor 1 beta central acidic region GATA PF00320.27 OAG39060.1 - 2e-15 56.1 2.6 4e-15 55.1 2.6 1.5 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.12 OAG39060.1 - 0.017 14.7 0.3 0.033 13.7 0.3 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding FAM76 PF16046.5 OAG39060.1 - 2.8 7.2 9.0 38 3.5 9.2 2.2 1 1 0 1 1 1 0 FAM76 protein AMP-binding PF00501.28 OAG39061.1 - 1.5e-72 244.6 0.0 1.8e-72 244.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG39061.1 - 1.3e-17 64.5 0.8 2.5e-17 63.6 0.8 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF2773 PF10971.8 OAG39061.1 - 0.13 12.4 0.1 0.38 10.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2773) Na_Ca_ex PF01699.24 OAG39062.1 - 1.8e-33 115.7 34.3 3.2e-18 66.1 16.3 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Ost5 PF05251.12 OAG39062.1 - 0.011 16.0 2.1 0.011 16.0 2.1 4.3 4 1 1 5 5 5 0 Oligosaccharyltransferase subunit 5 Rgp1 PF08737.10 OAG39063.1 - 3.3e-123 411.9 0.0 6.1e-123 411.1 0.0 1.4 1 0 0 1 1 1 1 Rgp1 Arrestin_N PF00339.29 OAG39063.1 - 0.0024 17.9 0.0 0.0047 17.0 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 OAG39063.1 - 0.14 12.6 0.0 2.4 8.6 0.0 2.6 2 0 0 2 2 2 0 Arrestin (or S-antigen), C-terminal domain Diphthamide_syn PF01866.17 OAG39064.1 - 6.5e-116 387.0 0.0 8.2e-116 386.7 0.0 1.0 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Rhomboid PF01694.22 OAG39065.1 - 4.6e-06 26.7 2.1 4.6e-06 26.7 2.1 1.6 2 0 0 2 2 2 1 Rhomboid family DUF1751 PF08551.10 OAG39065.1 - 9.6e-05 22.9 2.9 0.00018 22.0 2.9 1.4 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) BSD PF03909.17 OAG39066.1 - 4.4e-24 84.3 6.2 2.1e-13 50.0 0.6 3.0 3 0 0 3 3 3 2 BSD domain PH_TFIIH PF08567.11 OAG39066.1 - 4.6e-24 84.6 0.0 1e-23 83.4 0.0 1.6 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain PTB PF08416.13 OAG39066.1 - 0.1 12.8 0.1 3.5 7.8 0.1 2.8 3 0 0 3 3 3 0 Phosphotyrosine-binding domain Pkinase PF00069.25 OAG39067.1 - 1.2e-22 80.5 0.0 5.1e-12 45.7 0.0 2.6 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAG39067.1 - 1.2e-06 28.0 0.0 0.013 14.8 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase TRI12 PF06609.13 OAG39068.1 - 6.9e-75 252.6 21.9 8.6e-75 252.3 21.9 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG39068.1 - 1.1e-23 83.7 55.8 2.6e-22 79.2 51.6 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG39068.1 - 9.1e-11 41.3 9.9 9.1e-11 41.3 9.9 2.9 4 0 0 4 4 4 2 Sugar (and other) transporter Pox_A14 PF05767.12 OAG39068.1 - 2.7 8.2 8.2 0.33 11.1 1.5 2.8 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 adh_short_C2 PF13561.6 OAG39069.1 - 5.5e-65 219.2 0.1 7e-65 218.9 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG39069.1 - 1e-47 162.2 0.1 1.2e-47 161.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG39069.1 - 2.1e-13 50.6 0.3 2.9e-13 50.1 0.3 1.1 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 OAG39069.1 - 0.0074 16.2 0.2 0.012 15.6 0.2 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ldh_1_N PF00056.23 OAG39069.1 - 0.02 15.0 0.3 0.035 14.2 0.3 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Methyltransf_25 PF13649.6 OAG39069.1 - 0.028 15.1 0.1 0.058 14.1 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain Fungal_trans PF04082.18 OAG39070.1 - 9.9e-18 64.1 0.2 1.5e-17 63.5 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain SGL PF08450.12 OAG39071.1 - 2.2e-09 37.3 0.0 6.3e-09 35.8 0.0 1.7 2 0 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region MFS_1 PF07690.16 OAG39072.1 - 2.2e-15 56.5 51.5 2.9e-10 39.6 40.4 3.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_S28 PF05577.12 OAG39073.1 - 7.1e-40 137.1 0.0 1.1e-39 136.5 0.0 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase S28 SSP160 PF06933.11 OAG39074.1 - 2 6.5 18.8 2.5 6.2 18.8 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 FSA_C PF10479.9 OAG39074.1 - 6.4 4.8 11.3 8.1 4.4 11.3 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus DUF4381 PF14316.6 OAG39075.1 - 0.003 17.8 1.0 0.0061 16.8 1.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4381) LapA_dom PF06305.11 OAG39075.1 - 0.025 14.4 2.7 0.047 13.5 2.7 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain SF1-HH PF16275.5 OAG39076.1 - 0.092 13.1 0.0 0.15 12.4 0.0 1.3 1 0 0 1 1 1 0 Splicing factor 1 helix-hairpin domain NHL PF01436.21 OAG39076.1 - 0.19 11.9 0.1 0.53 10.4 0.0 1.8 2 0 0 2 2 2 0 NHL repeat Far-17a_AIG1 PF04750.14 OAG39077.1 - 1.8e-55 187.4 9.1 2e-55 187.2 9.1 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein Fungal_trans_2 PF11951.8 OAG39078.1 - 3.3e-63 213.8 0.3 5.1e-63 213.2 0.3 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pam17 PF08566.10 OAG39079.1 - 1.1e-58 197.8 0.0 1.4e-58 197.3 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 Colicin_V PF02674.16 OAG39079.1 - 0.071 13.1 0.1 0.1 12.6 0.1 1.2 1 0 0 1 1 1 0 Colicin V production protein FixQ PF05545.11 OAG39081.1 - 0.028 14.4 0.8 0.12 12.4 0.2 2.4 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ TMEM192 PF14802.6 OAG39081.1 - 0.045 12.9 0.6 2.4 7.2 0.3 2.2 2 0 0 2 2 2 0 TMEM192 family CytochromB561_N PF09786.9 OAG39081.1 - 0.18 10.8 4.3 0.075 12.0 0.1 2.2 2 0 0 2 2 2 0 Cytochrome B561, N terminal AICARFT_IMPCHas PF01808.18 OAG39083.1 - 3.1e-92 309.2 0.0 4.6e-92 308.6 0.0 1.3 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 OAG39083.1 - 2.7e-13 49.9 0.1 4.8e-13 49.1 0.1 1.5 1 0 0 1 1 1 1 MGS-like domain Dis3l2_C_term PF17877.1 OAG39083.1 - 0.056 13.8 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 DIS3-like exonuclease 2 C terminal p450 PF00067.22 OAG39084.1 - 1.6e-55 188.7 0.0 2.4e-55 188.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PPTA PF01239.22 OAG39085.1 - 7.4e-37 124.0 20.1 5.6e-08 32.3 1.8 5.3 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat GHMP_kinases_N PF00288.26 OAG39086.1 - 2.5e-16 59.7 0.0 7.1e-16 58.2 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 OAG39086.1 - 1.4e-06 28.6 0.0 2.9e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.9 OAG39086.1 - 0.0087 15.6 0.1 0.017 14.6 0.1 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature Ric8 PF10165.9 OAG39087.1 - 1.3e-113 380.4 2.9 1.5e-113 380.2 2.9 1.0 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn Rif1_N PF12231.8 OAG39088.1 - 1.4e-112 376.4 1.7 2.5e-112 375.6 1.7 1.4 1 0 0 1 1 1 1 Rap1-interacting factor 1 N terminal MPC PF03650.13 OAG39089.1 - 5.4e-30 103.8 0.2 1.2e-18 67.3 0.0 2.2 2 0 0 2 2 2 2 Mitochondrial pyruvate carriers DUF1122 PF06557.11 OAG39089.1 - 0.14 11.6 1.2 0.21 11.0 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1122) CPSase_L_D2 PF02786.17 OAG39090.1 - 3.7e-82 274.9 0.1 5.7e-82 274.3 0.1 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 OAG39090.1 - 7.4e-71 238.0 0.1 1.4e-70 237.1 0.1 1.5 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_carb_N PF00289.22 OAG39090.1 - 7.8e-39 132.6 0.1 1.5e-38 131.7 0.1 1.5 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 OAG39090.1 - 1.3e-30 105.7 0.0 3.2e-30 104.4 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 OAG39090.1 - 6e-26 91.6 0.0 2.8e-25 89.4 0.0 2.0 1 1 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 OAG39090.1 - 3.3e-18 65.3 3.8 3.3e-18 65.3 3.8 2.3 2 0 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 OAG39090.1 - 7.3e-10 38.7 0.0 1.4e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.6 OAG39090.1 - 1.9e-09 37.2 2.4 8.3e-05 22.3 0.1 3.3 2 1 1 3 3 3 2 Biotin-lipoyl like ATP-grasp PF02222.22 OAG39090.1 - 1.9e-07 30.8 0.1 4.3e-07 29.7 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 OAG39090.1 - 4.4e-05 23.6 0.0 8.2e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 OAG39090.1 - 8.9e-05 22.2 0.0 0.00022 20.9 0.0 1.6 1 1 0 1 1 1 1 RimK-like ATP-grasp domain HlyD_3 PF13437.6 OAG39090.1 - 0.0017 19.0 0.3 0.96 10.2 0.0 3.0 3 0 0 3 3 3 1 HlyD family secretion protein HlyD_D23 PF16576.5 OAG39090.1 - 0.0026 17.0 0.1 0.17 11.1 0.0 2.3 1 1 1 2 2 2 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion ATP-grasp_4 PF13535.6 OAG39090.1 - 0.017 14.7 0.1 0.048 13.3 0.0 1.9 2 0 0 2 2 2 0 ATP-grasp domain GARS_A PF01071.19 OAG39090.1 - 0.027 14.2 0.0 0.056 13.2 0.0 1.5 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain DUF2118 PF09891.9 OAG39090.1 - 0.037 14.0 0.1 0.12 12.4 0.1 1.9 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) ATPgrasp_ST PF14397.6 OAG39090.1 - 0.071 12.4 0.0 0.17 11.1 0.0 1.5 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp GCV_H PF01597.19 OAG39090.1 - 0.093 12.6 1.3 0.5 10.3 0.4 2.7 2 1 1 3 3 3 0 Glycine cleavage H-protein RnfC_N PF13375.6 OAG39090.1 - 0.17 11.9 1.2 1.4 9.0 1.3 2.2 1 1 1 2 2 2 0 RnfC Barrel sandwich hybrid domain Clathrin PF00637.20 OAG39091.1 - 4.8e-201 658.7 36.8 2.2e-33 115.1 0.9 8.2 8 0 0 8 8 8 7 Region in Clathrin and VPS Clathrin_H_link PF13838.6 OAG39091.1 - 3.3e-33 113.4 3.4 1.2e-32 111.6 0.7 3.4 3 1 1 4 4 4 1 Clathrin-H-link Clathrin_propel PF01394.20 OAG39091.1 - 1.4e-27 94.6 2.1 8.2e-07 29.0 0.1 6.3 6 0 0 6 6 6 5 Clathrin propeller repeat TPR_7 PF13176.6 OAG39091.1 - 7.1e-05 22.6 9.4 7.6 6.8 0.0 7.7 7 0 0 7 7 7 1 Tetratricopeptide repeat Vps39_1 PF10366.9 OAG39091.1 - 0.00017 21.8 5.3 3.1 8.1 0.0 5.8 5 0 0 5 5 4 1 Vacuolar sorting protein 39 domain 1 TPR_1 PF00515.28 OAG39091.1 - 0.00023 20.8 3.3 4.7 7.2 0.0 5.7 5 0 0 5 5 5 2 Tetratricopeptide repeat Clathrin-link PF09268.10 OAG39091.1 - 0.00037 19.8 3.0 0.0039 16.5 1.1 2.6 2 0 0 2 2 2 1 Clathrin, heavy-chain linker TPR_14 PF13428.6 OAG39091.1 - 0.0013 19.4 16.1 9.7 7.3 0.0 9.9 11 1 1 12 12 11 1 Tetratricopeptide repeat TPR_8 PF13181.6 OAG39091.1 - 0.0035 17.4 2.6 3.3 8.1 0.0 5.7 5 0 0 5 5 4 1 Tetratricopeptide repeat Coatomer_WDAD PF04053.14 OAG39091.1 - 0.0039 16.3 9.4 0.47 9.4 0.2 4.0 3 0 0 3 3 3 2 Coatomer WD associated region TPR_12 PF13424.6 OAG39091.1 - 0.0075 16.5 11.1 5.4 7.4 0.0 6.9 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_2 PF07719.17 OAG39091.1 - 0.011 15.8 12.4 7.2 7.0 0.0 7.6 8 0 0 8 8 7 0 Tetratricopeptide repeat 6PF2K PF01591.18 OAG39091.1 - 0.019 14.2 1.1 0.14 11.5 0.2 2.4 2 0 0 2 2 2 0 6-phosphofructo-2-kinase DUF1400 PF07176.11 OAG39091.1 - 0.1 12.9 3.2 12 6.2 0.1 4.0 3 0 0 3 3 3 0 Alpha/beta hydrolase of unknown function (DUF1400) DUF1720 PF08226.11 OAG39091.1 - 0.26 11.7 8.3 0.13 12.7 4.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1720) TPR_10 PF13374.6 OAG39091.1 - 5.2 7.1 10.6 68 3.5 0.0 6.3 8 0 0 8 8 8 0 Tetratricopeptide repeat ADK PF00406.22 OAG39092.1 - 1.5e-44 151.7 0.0 1.8e-44 151.5 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 OAG39092.1 - 1.1e-34 119.8 0.0 1.4e-34 119.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 OAG39092.1 - 3e-11 44.0 0.0 3.9e-11 43.6 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 OAG39092.1 - 4.9e-07 30.0 0.1 6.8e-06 26.3 0.1 2.1 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 OAG39092.1 - 0.0011 18.6 0.3 0.96 9.1 0.0 2.2 2 0 0 2 2 2 2 Thymidylate kinase Ploopntkinase3 PF18751.1 OAG39092.1 - 0.12 12.3 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 WD40 PF00400.32 OAG39093.1 - 2.7e-09 37.5 0.0 0.073 14.0 0.1 5.7 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG39093.1 - 0.00073 19.8 0.1 2.4 8.5 0.0 4.2 5 0 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain BBS1 PF14779.6 OAG39093.1 - 0.046 13.1 0.0 0.32 10.4 0.0 2.1 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 1 Myb_DNA-bind_6 PF13921.6 OAG39094.1 - 5.3e-16 58.6 2.8 7.2e-16 58.2 0.0 2.6 3 0 0 3 3 3 1 Myb-like DNA-binding domain HSA PF07529.13 OAG39094.1 - 2.6e-10 40.4 0.2 2.6e-10 40.4 0.2 4.7 6 0 0 6 6 6 1 HSA Myb_DNA-binding PF00249.31 OAG39094.1 - 0.00012 22.2 0.1 0.00032 20.8 0.1 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain PCI PF01399.27 OAG39095.1 - 3.1e-12 46.9 0.1 1e-11 45.2 0.0 1.9 2 0 0 2 2 2 1 PCI domain eIF3m_C_helix PF18005.1 OAG39095.1 - 2e-10 40.2 2.7 4.2e-10 39.1 2.7 1.6 1 0 0 1 1 1 1 eIF3 subunit M, C-terminal helix MAT1 PF06391.13 OAG39096.1 - 3.6e-22 79.2 6.5 4.6e-22 78.9 6.5 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_5 PF17121.5 OAG39096.1 - 5.8e-16 58.1 6.7 9.6e-16 57.4 6.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAG39096.1 - 5.2e-05 23.0 3.5 0.00011 22.0 3.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OAG39096.1 - 0.0005 19.9 5.9 0.00063 19.5 0.4 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAG39096.1 - 0.0048 16.8 8.6 0.03 14.3 8.7 2.0 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 OAG39096.1 - 0.005 16.7 6.3 0.011 15.6 6.3 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAG39096.1 - 0.018 15.4 6.4 0.031 14.6 6.4 1.4 1 0 0 1 1 1 0 Ring finger domain zf-RING_UBOX PF13445.6 OAG39096.1 - 0.046 13.8 6.1 0.09 12.8 6.1 1.5 1 0 0 1 1 1 0 RING-type zinc-finger Prok-RING_4 PF14447.6 OAG39096.1 - 0.18 11.7 7.4 0.14 12.1 1.8 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 OAG39096.1 - 0.71 9.5 7.1 1.5 8.5 7.1 1.5 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type Prefoldin_3 PF13758.6 OAG39097.1 - 1.2e-20 73.4 0.0 4.7e-20 71.5 0.0 2.1 1 0 0 1 1 1 1 Prefoldin subunit DUF3835 PF12927.7 OAG39097.1 - 3e-19 69.6 2.8 2.2e-18 66.9 0.3 4.0 4 1 0 4 4 4 2 Domain of unknown function (DUF3835) HR1 PF02185.16 OAG39097.1 - 0.63 10.2 6.6 0.34 11.0 0.4 3.1 3 0 0 3 3 3 0 Hr1 repeat MFS_1 PF07690.16 OAG39098.1 - 5.7e-44 150.5 48.2 2.4e-42 145.2 47.2 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 OAG39098.1 - 5e-14 51.6 26.2 1.2e-13 50.3 26.2 1.7 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 OAG39098.1 - 2.5e-09 36.5 12.4 2.5e-09 36.5 12.4 3.6 3 1 1 4 4 4 3 Sugar (and other) transporter Acetyltransf_3 PF13302.7 OAG39099.1 - 2.2e-15 57.5 0.0 2.8e-15 57.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAG39099.1 - 5e-07 30.0 0.0 7.2e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 OAG39099.1 - 0.0011 19.1 0.0 0.0014 18.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain AT_hook PF02178.19 OAG39101.1 - 0.00068 19.2 5.8 0.046 13.6 1.0 3.1 2 0 0 2 2 2 2 AT hook motif Aldose_epim PF01263.20 OAG39102.1 - 3.7e-43 148.0 0.0 4.1e-43 147.8 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase DUF4360 PF14273.6 OAG39102.1 - 0.017 15.0 0.1 0.027 14.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4360) DUF4432 PF14486.6 OAG39102.1 - 0.13 11.0 0.0 0.2 10.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4432) Sigma70_r4_2 PF08281.12 OAG39103.1 - 0.049 13.3 0.0 0.077 12.7 0.0 1.3 1 0 0 1 1 1 0 Sigma-70, region 4 DUF3235 PF11574.8 OAG39103.1 - 0.16 12.8 2.5 0.31 11.9 2.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3235) DUF1330 PF07045.11 OAG39104.1 - 0.16 12.3 0.0 0.26 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1330) RNA_polI_A14 PF08203.11 OAG39105.1 - 0.00029 21.5 0.0 0.00029 21.5 0.0 3.1 2 1 1 3 3 3 1 Yeast RNA polymerase I subunit RPA14 SHR3_chaperone PF08229.11 OAG39106.1 - 5.5e-77 257.0 0.0 6.5e-77 256.8 0.0 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 MFS_1 PF07690.16 OAG39106.1 - 0.029 13.3 3.9 0.19 10.6 5.1 1.6 2 0 0 2 2 2 0 Major Facilitator Superfamily Phage_Gp23 PF10669.9 OAG39106.1 - 0.2 12.0 1.1 0.34 11.2 0.2 1.8 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) Helo_like_N PF17111.5 OAG39107.1 - 0.00016 21.1 1.7 0.00016 21.1 1.7 2.7 1 1 1 3 3 3 1 Fungal N-terminal domain of STAND proteins Apolipoprotein PF01442.18 OAG39107.1 - 0.016 15.1 6.4 0.033 14.1 0.6 2.5 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain APC1_C PF18122.1 OAG39107.1 - 0.096 12.6 0.6 0.49 10.3 0.0 2.4 3 0 0 3 3 3 0 Anaphase-promoting complex sub unit 1 C-terminal domain KELK PF15796.5 OAG39107.1 - 0.14 12.6 4.4 0.24 11.9 0.3 3.2 3 0 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Laminin_II PF06009.12 OAG39107.1 - 0.97 9.4 5.6 1.4 8.9 0.6 3.4 3 1 1 4 4 4 0 Laminin Domain II NPV_P10 PF05531.12 OAG39107.1 - 1.3 9.5 8.3 6.2 7.4 0.4 4.4 4 3 1 5 5 5 0 Nucleopolyhedrovirus P10 protein Cor1 PF04803.12 OAG39107.1 - 2.1 8.5 5.7 7.1 6.8 0.0 3.6 4 0 0 4 4 4 0 Cor1/Xlr/Xmr conserved region Peptidase_M48_N PF16491.5 OAG39109.1 - 1.2e-65 220.9 9.0 1.2e-65 220.9 9.0 1.7 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 OAG39109.1 - 1.4e-47 162.0 0.0 2.9e-47 161.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M48 BATS PF06968.13 OAG39109.1 - 6.5e-23 80.7 0.0 1.5e-22 79.5 0.0 1.7 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 OAG39109.1 - 3.3e-13 50.3 0.1 6.9e-13 49.3 0.1 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Peptidase_M56 PF05569.11 OAG39109.1 - 0.0033 16.7 0.1 0.0069 15.6 0.1 1.5 1 0 0 1 1 1 1 BlaR1 peptidase M56 DUF4538 PF15061.6 OAG39109.1 - 0.015 15.0 0.7 0.042 13.6 0.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4538) DUF1640 PF07798.11 OAG39110.1 - 1.2e-48 165.5 13.4 1.6e-48 165.1 13.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) FapA PF03961.13 OAG39110.1 - 0.38 9.3 2.1 0.48 9.0 2.1 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF1676 PF07898.13 OAG39110.1 - 1.9 8.5 4.9 2.9 7.9 4.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) SKA2 PF16740.5 OAG39111.1 - 0.0021 17.8 3.7 0.0028 17.4 1.8 2.3 2 0 0 2 2 2 1 Spindle and kinetochore-associated protein 2 Paralemmin PF03285.15 OAG39111.1 - 0.087 12.4 0.8 0.21 11.2 0.8 1.7 1 0 0 1 1 1 0 Paralemmin GAS PF13851.6 OAG39111.1 - 0.21 10.9 6.1 0.69 9.2 0.8 2.7 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Lzipper-MIP1 PF14389.6 OAG39111.1 - 0.55 10.6 7.2 0.2 12.0 1.8 2.8 2 1 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Filament PF00038.21 OAG39111.1 - 1.2 8.7 12.9 0.033 13.8 4.0 2.5 2 1 0 2 2 2 0 Intermediate filament protein Fmp27_WPPW PF10359.9 OAG39111.1 - 2.7 6.8 8.0 0.55 9.0 3.3 1.9 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain Seryl_tRNA_N PF02403.22 OAG39111.1 - 3.8 7.8 6.6 1.4 9.2 2.0 2.5 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Jnk-SapK_ap_N PF09744.9 OAG39111.1 - 4 7.7 11.8 3.1 8.0 2.1 2.8 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 adh_short PF00106.25 OAG39113.1 - 1.2e-32 113.0 0.2 1.8e-32 112.4 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG39113.1 - 2.6e-22 79.5 0.3 3.6e-22 79.1 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG39113.1 - 0.00027 20.9 0.1 0.003 17.5 0.0 2.3 2 0 0 2 2 2 1 KR domain Ilm1 PF10311.9 OAG39114.1 - 5.3e-21 75.0 1.5 5.2e-11 42.5 0.4 2.7 2 1 0 2 2 2 2 Increased loss of mitochondrial DNA protein 1 Ndc1_Nup PF09531.10 OAG39114.1 - 0.34 9.5 6.2 0.023 13.4 0.8 1.7 2 1 0 2 2 2 0 Nucleoporin protein Ndc1-Nup CFEM PF05730.11 OAG39115.1 - 3.4e-10 39.9 14.3 3.4e-10 39.9 14.3 1.9 2 0 0 2 2 2 1 CFEM domain Miga PF10265.9 OAG39115.1 - 3.1 6.7 10.6 3.9 6.3 10.6 1.1 1 0 0 1 1 1 0 Mitoguardin HET PF06985.11 OAG39116.1 - 1.4e-22 80.6 0.0 3.3e-22 79.4 0.0 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.16 OAG39117.1 - 3.1e-28 98.7 29.8 3.1e-28 98.7 29.8 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG39117.1 - 2.7e-07 29.8 12.4 2.7e-07 29.8 12.4 2.1 2 1 1 3 3 3 1 Sugar (and other) transporter 14-3-3 PF00244.20 OAG39118.1 - 6.8e-108 359.3 2.7 8e-108 359.1 2.7 1.0 1 0 0 1 1 1 1 14-3-3 protein E1-E2_ATPase PF00122.20 OAG39119.1 - 1e-52 178.3 5.7 2e-51 174.1 2.1 2.7 2 0 0 2 2 2 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 OAG39119.1 - 6.1e-45 153.2 5.8 6.1e-45 153.2 5.8 2.2 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 OAG39119.1 - 5.5e-22 79.1 1.7 5.5e-22 79.1 1.7 2.2 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 OAG39119.1 - 4e-20 71.3 0.1 1.3e-19 69.6 0.0 1.9 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 OAG39119.1 - 8.2e-18 64.3 0.0 2e-17 63.0 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 OAG39119.1 - 8.8e-09 35.5 2.6 2.6e-06 27.4 1.0 3.1 4 0 0 4 4 4 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 OAG39119.1 - 1.1e-05 26.0 0.0 6.1e-05 23.5 0.0 2.4 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase WD40 PF00400.32 OAG39120.1 - 8.5e-13 48.6 9.2 1.4e-05 25.7 0.2 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat DUF4831 PF16115.5 OAG39120.1 - 0.067 12.2 1.1 0.33 9.9 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4831) DUF4834 PF16118.5 OAG39120.1 - 4.3 8.4 5.7 10 7.2 5.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Spt20 PF12090.8 OAG39120.1 - 4.7 6.7 24.9 2 8.0 21.9 1.9 2 0 0 2 2 2 0 Spt20 family PAT1 PF09770.9 OAG39120.1 - 10 4.3 14.0 16 3.6 14.0 1.4 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CTP_transf_like PF01467.26 OAG39121.1 - 0.0025 18.0 0.9 0.17 12.1 0.2 2.3 2 0 0 2 2 2 2 Cytidylyltransferase-like FAD_syn PF06574.12 OAG39121.1 - 0.077 12.9 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 FAD synthetase zf-C2H2 PF00096.26 OAG39122.1 - 0.19 12.2 0.4 0.39 11.3 0.4 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type Prenyltrans PF00432.21 OAG39123.1 - 8.5e-57 188.6 6.3 6.2e-13 48.3 0.0 6.1 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 OAG39123.1 - 1.2e-06 27.8 0.0 0.047 12.8 0.0 3.5 2 2 2 4 4 4 2 Squalene-hopene cyclase N-terminal domain SQHop_cyclase_C PF13243.6 OAG39123.1 - 1.8e-06 27.3 0.0 0.041 13.0 0.0 3.1 1 1 2 3 3 3 3 Squalene-hopene cyclase C-terminal domain RhoGAP PF00620.27 OAG39124.1 - 1.5e-29 102.8 0.0 2.4e-29 102.1 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain TAF4 PF05236.14 OAG39124.1 - 0.48 10.1 5.6 1.2 8.8 5.6 1.6 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family RRS1 PF04939.12 OAG39125.1 - 1.2e-54 184.6 0.6 1.5e-54 184.2 0.6 1.1 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) CBS PF00571.28 OAG39127.1 - 4.5e-35 119.9 4.6 5.7e-09 36.3 0.0 5.2 5 0 0 5 5 5 4 CBS domain PB1 PF00564.24 OAG39127.1 - 1.5e-10 40.9 0.1 5.3e-10 39.1 0.0 2.1 2 0 0 2 2 2 1 PB1 domain AAA PF00004.29 OAG39128.1 - 5.1e-56 188.7 0.0 2.7e-43 147.6 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.11 OAG39128.1 - 2.3e-28 98.4 1.5 7.8e-28 96.7 1.6 1.9 2 0 0 2 2 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_lid_3 PF17862.1 OAG39128.1 - 3.9e-13 49.0 0.0 1.7e-07 30.9 0.0 2.6 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 OAG39128.1 - 3e-10 40.7 5.7 0.00023 21.6 0.2 4.7 3 2 0 4 4 4 2 AAA ATPase domain AAA_2 PF07724.14 OAG39128.1 - 5.6e-09 36.3 0.0 0.0008 19.6 0.0 2.8 3 0 0 3 3 3 2 AAA domain (Cdc48 subfamily) NACHT PF05729.12 OAG39128.1 - 4.3e-06 26.7 0.1 0.0034 17.3 0.0 3.1 3 0 0 3 3 3 1 NACHT domain TIP49 PF06068.13 OAG39128.1 - 7e-06 25.5 0.0 0.0074 15.5 0.0 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain RuvB_N PF05496.12 OAG39128.1 - 9.9e-06 25.4 0.0 0.015 15.0 0.0 2.7 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 OAG39128.1 - 3.8e-05 23.7 0.0 0.43 10.6 0.0 3.0 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 OAG39128.1 - 0.00013 21.7 0.0 0.19 11.4 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein TsaE PF02367.17 OAG39128.1 - 0.00019 21.4 0.0 0.25 11.3 0.0 2.8 3 0 0 3 3 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 OAG39128.1 - 0.00027 21.2 1.0 1.2 9.4 0.2 3.1 2 2 1 3 3 3 2 AAA domain AAA_14 PF13173.6 OAG39128.1 - 0.00027 20.9 0.0 1.3 9.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 OAG39128.1 - 0.001 19.6 0.0 1.6 9.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 OAG39128.1 - 0.0012 19.2 0.0 2.7 8.4 0.0 2.5 2 0 0 2 2 2 2 RNA helicase Mg_chelatase PF01078.21 OAG39128.1 - 0.0016 17.9 0.0 0.79 9.1 0.1 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 OAG39128.1 - 0.0016 17.7 0.0 0.68 9.2 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_7 PF12775.7 OAG39128.1 - 0.002 17.6 0.0 0.16 11.5 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region ABC_tran PF00005.27 OAG39128.1 - 0.0026 18.3 0.0 3.2 8.3 0.0 2.7 2 0 0 2 2 2 1 ABC transporter AAA_33 PF13671.6 OAG39128.1 - 0.0056 16.8 0.0 0.64 10.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 OAG39128.1 - 0.0073 16.2 0.0 0.18 11.7 0.0 2.3 2 0 0 2 2 2 1 NTPase Sigma54_activat PF00158.26 OAG39128.1 - 0.011 15.4 0.0 1.2 8.8 0.0 2.7 2 1 0 2 2 2 0 Sigma-54 interaction domain Vps4_C PF09336.10 OAG39128.1 - 0.019 14.9 0.1 6.5 6.8 0.0 2.6 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain cobW PF02492.19 OAG39128.1 - 0.019 14.5 0.2 0.27 10.8 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.6 OAG39128.1 - 0.03 14.5 0.0 6.9 6.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 OAG39128.1 - 0.041 14.2 0.0 0.61 10.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 OAG39128.1 - 0.056 13.2 0.0 1.4 8.6 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation T2SSE PF00437.20 OAG39128.1 - 0.064 12.3 0.4 0.36 9.9 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_17 PF13207.6 OAG39128.1 - 0.076 13.4 0.0 3.4 8.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 OAG39128.1 - 0.14 11.8 4.2 1.4 8.4 0.1 3.6 2 2 2 4 4 4 0 AAA domain APS_kinase PF01583.20 OAG39128.1 - 0.14 12.0 0.1 0.92 9.4 0.0 2.2 2 0 0 2 2 2 0 Adenylylsulphate kinase ATPase PF06745.13 OAG39128.1 - 0.15 11.4 0.0 13 5.1 0.0 2.3 2 0 0 2 2 2 0 KaiC DUF815 PF05673.13 OAG39128.1 - 0.19 10.9 0.0 3.5 6.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_24 PF13479.6 OAG39128.1 - 0.2 11.4 0.1 17 5.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain MCM PF00493.23 OAG39129.1 - 1.3e-103 345.0 0.0 2e-103 344.3 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 OAG39129.1 - 4.3e-31 107.4 0.3 8e-31 106.5 0.3 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_N PF14551.6 OAG39129.1 - 3.7e-21 75.7 1.7 9.6e-21 74.3 1.7 1.7 1 0 0 1 1 1 1 MCM N-terminal domain MCM_lid PF17855.1 OAG39129.1 - 2e-20 73.0 0.2 5.6e-20 71.6 0.2 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 OAG39129.1 - 5.8e-07 29.1 0.0 5.6e-05 22.6 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 OAG39129.1 - 3.5e-06 27.1 0.0 1.4e-05 25.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_lid_2 PF17863.1 OAG39129.1 - 0.016 15.1 0.0 0.052 13.4 0.0 1.8 1 0 0 1 1 1 0 AAA lid domain AAA_3 PF07726.11 OAG39129.1 - 0.034 14.0 0.0 0.12 12.3 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase_C PF13335.6 OAG39129.1 - 0.035 14.7 0.0 0.14 12.8 0.0 2.0 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI C-terminal ApoLp-III PF07464.11 OAG39129.1 - 0.087 12.9 1.0 0.17 12.0 0.2 1.8 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Cyclase PF04199.13 OAG39130.1 - 3.8e-14 53.1 0.1 6.7e-14 52.3 0.1 1.4 1 0 0 1 1 1 1 Putative cyclase DAP3 PF10236.9 OAG39131.1 - 3.3e-78 263.0 0.0 4.4e-78 262.6 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.6 OAG39131.1 - 0.028 14.8 0.1 0.082 13.3 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.6 OAG39131.1 - 0.032 14.0 0.0 0.19 11.5 0.0 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain Ribosomal_S26e PF01283.19 OAG39132.1 - 1.7e-50 170.0 9.4 2e-50 169.7 9.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S26e Fer4_7 PF12838.7 OAG39132.1 - 0.023 15.3 1.2 0.59 10.8 0.4 2.3 2 1 0 2 2 2 0 4Fe-4S dicluster domain DUF4668 PF15701.5 OAG39132.1 - 0.088 12.6 0.3 0.16 11.7 0.2 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4668) Q_salvage PF10343.9 OAG39132.1 - 0.1 12.2 0.0 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 Potential Queuosine, Q, salvage protein family zf_CopZ PF18423.1 OAG39132.1 - 0.12 12.4 1.8 0.14 12.1 0.0 2.0 3 0 0 3 3 3 0 Zinc binding domain Pkinase PF00069.25 OAG39133.1 - 3.9e-58 196.9 0.0 1.3e-57 195.1 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG39133.1 - 5.7e-28 97.9 0.0 8.2e-28 97.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OAG39133.1 - 0.00098 18.2 0.0 0.0014 17.7 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OAG39133.1 - 0.096 12.6 0.1 0.17 11.7 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family CBF PF03914.17 OAG39133.1 - 0.1 12.7 0.0 0.24 11.4 0.0 1.7 2 0 0 2 2 2 0 CBF/Mak21 family Sugar_tr PF00083.24 OAG39134.1 - 4.3e-95 319.2 18.0 5.2e-95 319.0 18.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG39134.1 - 3.4e-31 108.5 45.9 2.3e-21 76.1 17.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily BRI3BP PF14965.6 OAG39134.1 - 4.9 6.6 10.9 15 5.1 10.9 1.8 1 1 0 1 1 1 0 Negative regulator of p53/TP53 COesterase PF00135.28 OAG39135.1 - 1.8e-74 251.5 0.1 2.5e-74 251.0 0.1 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAG39135.1 - 1.6e-06 28.1 0.2 1.6e-05 24.9 0.2 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold CFEM PF05730.11 OAG39136.1 - 0.0029 17.7 3.0 0.016 15.3 0.2 2.6 2 0 0 2 2 2 1 CFEM domain CFEM PF05730.11 OAG39137.1 - 0.005 16.9 16.5 0.015 15.4 2.7 2.8 3 0 0 3 3 3 2 CFEM domain FMO-like PF00743.19 OAG39138.1 - 2.5e-10 39.4 1.3 1.1e-09 37.3 0.1 2.3 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 OAG39138.1 - 9e-05 21.8 0.0 0.00035 19.8 0.0 1.9 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 OAG39138.1 - 0.00032 20.0 0.0 0.022 14.0 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG39138.1 - 0.0016 17.8 0.0 0.0067 15.7 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG39138.1 - 0.0093 16.2 0.0 0.025 14.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 OAG39138.1 - 0.013 14.8 0.0 5.4 6.2 0.0 2.3 2 0 0 2 2 2 0 Thi4 family FMO-like PF00743.19 OAG39139.1 - 5.4e-19 68.0 0.7 3.3e-17 62.1 0.3 2.6 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OAG39139.1 - 1.3e-06 28.5 0.0 3.3e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 OAG39139.1 - 0.00017 20.9 0.0 0.0081 15.3 0.0 2.3 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 OAG39139.1 - 0.018 14.3 0.2 0.92 8.7 0.0 2.6 2 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG39139.1 - 0.038 13.2 0.0 0.77 9.0 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Amidase PF01425.21 OAG39140.1 - 3.6e-93 313.0 0.0 4.8e-93 312.6 0.0 1.2 1 0 0 1 1 1 1 Amidase p450 PF00067.22 OAG39141.1 - 5.1e-71 239.8 0.0 6.5e-71 239.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 adh_short_C2 PF13561.6 OAG39142.1 - 4.3e-48 163.9 0.0 5.7e-48 163.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG39142.1 - 1.2e-39 135.8 0.0 1.4e-39 135.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG39142.1 - 9.7e-12 45.1 0.0 2.2e-11 44.0 0.0 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG39142.1 - 3e-06 26.9 0.0 1e-05 25.1 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OAG39142.1 - 0.016 14.2 0.0 0.028 13.4 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF3425 PF11905.8 OAG39143.1 - 3.3e-08 33.5 0.2 4.4e-07 29.9 0.2 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 OAG39143.1 - 2.6e-05 24.2 3.0 0.0003 20.8 3.0 2.3 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 OAG39143.1 - 0.025 14.6 2.4 0.046 13.8 0.3 2.2 2 0 0 2 2 2 0 Basic region leucine zipper AtuA PF07287.11 OAG39144.1 - 1.1e-115 386.2 0.0 1.3e-115 385.9 0.0 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA SnoaL_4 PF13577.6 OAG39145.1 - 3.2e-21 75.8 0.0 3.6e-21 75.6 0.0 1.0 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_2 PF12680.7 OAG39145.1 - 0.027 15.1 0.0 0.039 14.6 0.0 1.3 1 1 0 1 1 1 0 SnoaL-like domain Scytalone_dh PF02982.14 OAG39145.1 - 0.03 14.1 0.0 0.051 13.4 0.0 1.3 1 0 0 1 1 1 0 Scytalone dehydratase Lumazine_bd_2 PF12893.7 OAG39145.1 - 0.034 14.8 0.0 0.056 14.1 0.0 1.4 1 0 0 1 1 1 0 Putative lumazine-binding Beta-lactamase PF00144.24 OAG39146.1 - 2.5e-38 132.1 0.0 3.9e-38 131.5 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase adh_short_C2 PF13561.6 OAG39147.1 - 7.9e-43 146.7 0.4 5.8e-34 117.7 0.2 2.9 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG39147.1 - 2.4e-38 131.6 0.1 1.7e-37 128.8 0.1 1.9 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG39147.1 - 8.5e-06 25.8 0.5 8.9e-05 22.5 0.5 2.1 1 1 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.8 OAG39147.1 - 0.00041 20.1 0.1 0.0027 17.4 0.0 2.2 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.21 OAG39147.1 - 0.031 13.7 0.0 0.048 13.1 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family bZIP_1 PF00170.21 OAG39148.1 - 6.9e-07 29.3 5.3 1.4e-06 28.3 5.3 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 OAG39148.1 - 0.015 15.3 7.5 0.41 10.8 1.2 2.2 2 0 0 2 2 2 0 Basic region leucine zipper YabA PF06156.13 OAG39148.1 - 0.052 14.2 0.7 0.099 13.3 0.6 1.5 1 1 0 1 1 1 0 Initiation control protein YabA GrpE PF01025.19 OAG39148.1 - 0.097 12.3 1.1 0.13 11.9 0.4 1.4 1 1 0 1 1 1 0 GrpE adh_short_C2 PF13561.6 OAG39149.1 - 1.6e-61 207.9 0.0 1.9e-61 207.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG39149.1 - 6.6e-50 169.3 0.1 7.6e-50 169.1 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG39149.1 - 9.4e-06 25.6 0.2 1.8e-05 24.7 0.2 1.5 1 1 0 1 1 1 1 KR domain Methyltransf_16 PF10294.9 OAG39149.1 - 0.024 14.4 0.0 0.034 13.9 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase AdoHcyase_NAD PF00670.21 OAG39149.1 - 0.043 13.9 0.2 0.067 13.3 0.2 1.3 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 3HCDH_N PF02737.18 OAG39149.1 - 0.054 13.4 0.2 0.1 12.5 0.2 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TRI12 PF06609.13 OAG39150.1 - 2.2e-148 495.4 19.2 2.7e-148 495.1 19.2 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG39150.1 - 1.3e-20 73.7 53.6 4.6e-18 65.3 27.1 3.0 2 1 1 3 3 3 2 Major Facilitator Superfamily TMEM141 PF15110.6 OAG39150.1 - 0.25 12.0 2.5 0.27 11.8 0.1 2.4 2 0 0 2 2 2 0 TMEM141 protein family Hydrolase_like PF13242.6 OAG39151.1 - 0.01 15.9 0.0 0.02 14.9 0.0 1.5 1 0 0 1 1 1 0 HAD-hyrolase-like Hydrolase PF00702.26 OAG39151.1 - 0.02 15.2 0.1 0.061 13.6 0.0 1.8 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 OAG39151.1 - 0.02 15.0 0.0 0.13 12.3 0.0 2.2 3 0 0 3 3 3 0 Haloacid dehalogenase-like hydrolase Methyltransf_31 PF13847.6 OAG39152.1 - 9.1e-11 41.8 0.0 3.3e-10 39.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG39152.1 - 3.4e-09 37.3 0.0 8.5e-09 36.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG39152.1 - 3.4e-08 34.0 0.0 6.6e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG39152.1 - 1.9e-07 31.8 0.0 4.6e-07 30.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAG39152.1 - 3e-07 30.4 0.0 7.2e-07 29.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAG39152.1 - 0.00038 19.9 0.0 0.0027 17.1 0.0 2.0 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 OAG39152.1 - 0.047 13.2 0.0 0.074 12.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_4 PF02390.17 OAG39152.1 - 0.049 13.1 0.0 0.14 11.6 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase CheR PF01739.18 OAG39152.1 - 0.15 11.5 0.1 0.38 10.2 0.0 1.6 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain Amidase PF01425.21 OAG39153.1 - 2.6e-86 290.4 0.3 4.1e-86 289.7 0.3 1.2 1 0 0 1 1 1 1 Amidase Aa_trans PF01490.18 OAG39154.1 - 7.9e-24 84.1 35.4 9.3e-24 83.9 35.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Fungal_trans_2 PF11951.8 OAG39155.1 - 2.2e-13 49.8 0.3 3.2e-13 49.3 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain RIBIOP_C PF04950.12 OAG39156.1 - 4.3e-97 325.1 0.0 4.3e-97 325.1 0.0 2.2 2 0 0 2 2 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 OAG39156.1 - 1.3e-28 98.9 0.0 4.6e-28 97.1 0.0 2.1 1 0 0 1 1 1 1 AARP2CN (NUC121) domain AAA_22 PF13401.6 OAG39156.1 - 0.00015 22.0 0.3 0.00068 19.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 OAG39156.1 - 0.0004 20.5 0.1 0.0015 18.6 0.1 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.6 OAG39156.1 - 0.00079 19.6 0.0 0.0027 17.9 0.0 2.0 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 OAG39156.1 - 0.00079 19.4 0.0 0.0016 18.4 0.0 1.5 1 0 0 1 1 1 1 NACHT domain GTP_EFTU PF00009.27 OAG39156.1 - 0.00084 18.9 0.0 0.13 11.8 0.0 2.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 OAG39156.1 - 0.00088 19.7 0.0 0.0035 17.7 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 OAG39156.1 - 0.0046 17.3 0.0 0.012 16.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 OAG39156.1 - 0.0083 16.6 0.8 0.027 15.0 0.0 2.2 2 0 0 2 2 1 1 ABC transporter AAA PF00004.29 OAG39156.1 - 0.011 16.2 0.0 0.025 15.0 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.9 OAG39156.1 - 0.011 15.4 0.1 0.091 12.5 0.1 2.1 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation MobB PF03205.14 OAG39156.1 - 0.012 15.5 0.8 0.18 11.7 0.0 2.9 2 1 1 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B NB-ARC PF00931.22 OAG39156.1 - 0.013 14.7 0.0 0.028 13.6 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_28 PF13521.6 OAG39156.1 - 0.023 14.9 2.9 0.061 13.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.14 OAG39156.1 - 0.029 13.6 0.0 0.058 12.6 0.0 1.5 1 0 0 1 1 1 0 KAP family P-loop domain Viral_helicase1 PF01443.18 OAG39156.1 - 0.046 13.4 0.0 0.095 12.4 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.22 OAG39156.1 - 0.051 14.0 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.6 OAG39156.1 - 0.052 13.1 0.9 0.21 11.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 OAG39156.1 - 0.054 13.1 0.1 0.11 12.1 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 OAG39156.1 - 0.058 13.3 0.0 0.21 11.5 0.0 1.9 1 0 0 1 1 1 0 RsgA GTPase AAA_18 PF13238.6 OAG39156.1 - 0.09 13.3 6.5 0.095 13.3 0.1 3.1 3 0 0 3 3 2 0 AAA domain AAA_7 PF12775.7 OAG39156.1 - 0.093 12.2 0.1 0.27 10.7 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region Roc PF08477.13 OAG39156.1 - 0.12 12.6 0.0 0.33 11.2 0.0 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase NTPase_1 PF03266.15 OAG39156.1 - 0.12 12.2 0.2 0.23 11.4 0.2 1.4 1 0 0 1 1 1 0 NTPase AAA_14 PF13173.6 OAG39156.1 - 0.15 12.1 0.1 0.53 10.3 0.1 1.9 1 0 0 1 1 1 0 AAA domain Whi5 PF08528.11 OAG39157.1 - 2.7e-13 49.2 0.2 5.4e-13 48.3 0.2 1.6 1 0 0 1 1 1 1 Whi5 like CAP PF00188.26 OAG39158.1 - 4.1e-20 72.9 3.9 5e-20 72.6 3.9 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family GST_N_3 PF13417.6 OAG39159.1 - 1.8e-07 31.5 0.0 4.3e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OAG39159.1 - 0.00012 22.3 0.0 0.00026 21.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OAG39159.1 - 0.031 14.5 0.8 0.17 12.1 0.8 2.1 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OAG39159.1 - 0.063 13.3 0.3 0.16 12.0 0.3 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 OAG39159.1 - 0.085 13.2 0.0 0.22 11.9 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain adh_short_C2 PF13561.6 OAG39160.1 - 2.2e-52 178.0 4.6 2.8e-48 164.5 4.6 3.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG39160.1 - 3.9e-44 150.5 1.2 2e-40 138.4 1.2 2.9 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG39160.1 - 0.0016 18.4 2.7 0.34 10.8 2.1 3.1 2 1 0 2 2 2 1 KR domain Epimerase PF01370.21 OAG39160.1 - 0.041 13.3 0.1 1.3 8.4 0.0 2.5 2 2 0 2 2 2 0 NAD dependent epimerase/dehydratase family AAA PF00004.29 OAG39161.1 - 1.2e-16 61.3 0.0 2.9e-16 60.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 OAG39161.1 - 0.0031 17.5 0.0 0.0084 16.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 OAG39161.1 - 0.0045 17.3 0.6 0.032 14.5 0.1 2.5 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 OAG39161.1 - 0.031 14.5 0.2 0.44 10.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 OAG39161.1 - 0.067 12.9 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 OAG39161.1 - 0.069 13.5 1.2 0.26 11.7 0.2 2.2 1 1 1 2 2 2 0 AAA ATPase domain AAA_11 PF13086.6 OAG39161.1 - 0.15 11.9 0.0 0.15 11.9 0.0 2.8 2 0 0 2 2 2 0 AAA domain ADH_zinc_N PF00107.26 OAG39163.1 - 7.1e-15 55.1 0.0 1.1e-14 54.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 OAG39163.1 - 2.8e-10 40.1 0.0 6.8e-10 38.8 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 OAG39163.1 - 0.00011 23.3 0.0 0.00019 22.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase IBR PF01485.21 OAG39164.1 - 2.3e-09 37.4 31.5 6.8e-07 29.4 8.0 3.3 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain Ldh_1_C PF02866.18 OAG39165.1 - 1.8e-48 164.6 0.0 3.9e-48 163.5 0.0 1.5 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 OAG39165.1 - 3.7e-43 147.0 0.0 5.5e-43 146.4 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 OAG39165.1 - 0.0002 20.4 0.0 0.00028 20.0 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 OAG39165.1 - 0.075 13.5 0.1 0.24 11.8 0.0 1.9 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain MFS_1 PF07690.16 OAG39166.1 - 1.2e-23 83.7 20.9 1.2e-23 83.7 20.9 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 OAG39166.1 - 0.0011 17.5 2.0 0.0016 17.0 2.0 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) UCH PF00443.29 OAG39167.1 - 5.5e-75 252.2 0.0 8.1e-75 251.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 OAG39167.1 - 2.2e-14 53.8 0.0 1.1e-13 51.6 0.0 2.3 2 0 0 2 2 2 1 DUSP domain UCH_1 PF13423.6 OAG39167.1 - 1.1e-12 48.2 0.7 0.00018 21.2 0.0 3.3 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase PX PF00787.24 OAG39168.1 - 1.7e-17 63.4 0.0 6.5e-17 61.5 0.0 2.0 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 OAG39168.1 - 4.2e-11 42.9 8.2 6.7e-07 29.1 0.4 2.1 2 0 0 2 2 2 2 Vps5 C terminal like Adeno_E3_CR2 PF02439.15 OAG39169.1 - 3.6 7.4 6.5 0.2 11.4 1.0 1.8 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 DUF2428 PF10350.9 OAG39170.1 - 2.4e-51 174.6 2.0 7.7e-51 173.0 2.0 1.9 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) Nipped-B_C PF12830.7 OAG39170.1 - 0.0077 16.2 0.1 0.04 13.8 0.0 2.3 3 0 0 3 3 3 1 Sister chromatid cohesion C-terminus HEAT PF02985.22 OAG39170.1 - 0.028 14.6 8.5 6.3 7.3 0.3 6.3 6 0 0 6 6 6 0 HEAT repeat HEAT_2 PF13646.6 OAG39170.1 - 0.031 14.6 1.1 5.4 7.5 0.1 3.6 3 0 0 3 3 3 0 HEAT repeats Tim17 PF02466.19 OAG39171.1 - 4.1e-28 98.0 2.9 6.5e-28 97.3 2.9 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF2953 PF11167.8 OAG39171.1 - 1.1 9.4 3.2 9.1 6.5 1.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2953) NAD_binding_10 PF13460.6 OAG39172.1 - 1.2e-10 41.6 0.0 1.3e-09 38.2 0.0 2.5 1 1 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 OAG39172.1 - 3.3e-06 26.3 0.0 2.1e-05 23.7 0.0 1.9 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 OAG39172.1 - 5.8e-06 25.9 0.0 2.2e-05 24.1 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 OAG39172.1 - 0.0015 17.7 0.1 0.077 12.1 0.0 2.9 2 1 0 2 2 2 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 OAG39172.1 - 0.0072 15.5 0.0 0.067 12.3 0.0 2.2 2 0 0 2 2 2 1 Male sterility protein GDP_Man_Dehyd PF16363.5 OAG39172.1 - 0.039 13.4 0.0 0.056 12.8 0.0 1.1 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase SYF2 PF08231.12 OAG39173.1 - 7.4e-48 162.9 17.3 7.4e-48 162.9 17.3 2.0 2 0 0 2 2 2 1 SYF2 splicing factor TetR_C_24 PF17932.1 OAG39173.1 - 0.017 15.4 1.6 0.11 12.8 0.4 2.5 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain DAO PF01266.24 OAG39174.1 - 9.1e-29 101.1 0.1 1e-28 100.9 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAG39174.1 - 0.00037 20.7 0.0 0.00089 19.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAG39174.1 - 0.0011 18.2 0.0 0.002 17.4 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Sacchrp_dh_NADP PF03435.18 OAG39174.1 - 0.0046 17.2 0.1 0.02 15.1 0.0 1.9 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain FAD_binding_3 PF01494.19 OAG39174.1 - 0.0051 16.1 0.0 0.0082 15.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 OAG39174.1 - 0.012 14.8 0.0 0.022 14.0 0.0 1.3 1 0 0 1 1 1 0 Thi4 family LPD38 PF18857.1 OAG39174.1 - 0.035 14.3 0.0 0.095 12.8 0.0 1.7 2 0 0 2 2 2 0 Large polyvalent protein associated domain 38 Trp_halogenase PF04820.14 OAG39174.1 - 0.046 12.6 0.0 0.066 12.0 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase FAD_binding_2 PF00890.24 OAG39174.1 - 0.067 12.3 0.0 0.29 10.2 0.0 1.8 2 0 0 2 2 2 0 FAD binding domain YEATS PF03366.16 OAG39175.1 - 3.5e-35 119.8 1.5 5.7e-35 119.1 1.5 1.4 1 0 0 1 1 1 1 YEATS family Velvet PF11754.8 OAG39177.1 - 1.5e-41 143.0 1.7 3.6e-39 135.2 0.0 3.0 2 1 0 2 2 2 1 Velvet factor Mucin PF01456.17 OAG39177.1 - 5.4 7.0 8.8 0.48 10.4 2.3 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein RNA_pol_3_Rpc31 PF11705.8 OAG39177.1 - 7.2 6.8 8.2 1.2 9.3 0.5 2.9 3 0 0 3 3 3 0 DNA-directed RNA polymerase III subunit Rpc31 Glyoxalase PF00903.25 OAG39178.1 - 1.5e-10 41.4 0.1 4.2e-10 39.9 0.1 1.7 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 OAG39178.1 - 3.5e-08 33.7 0.0 4.4e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 OAG39178.1 - 7.8e-05 22.6 0.0 0.00055 19.9 0.0 2.0 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_3 PF13468.6 OAG39178.1 - 0.00085 19.5 0.1 0.018 15.1 0.1 2.0 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_6 PF18029.1 OAG39178.1 - 0.0009 20.0 0.0 0.0022 18.8 0.0 1.7 1 1 0 1 1 1 1 Glyoxalase-like domain Pyr_redox PF00070.27 OAG39178.1 - 0.011 16.2 0.0 0.019 15.5 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase PrpR_N PF06506.11 OAG39178.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Propionate catabolism activator Lipase_3 PF01764.25 OAG39180.1 - 1.9e-18 66.7 0.0 3.7e-18 65.8 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 OAG39180.1 - 0.0061 17.2 1.1 0.011 16.3 0.2 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family TGBp3 PF02495.17 OAG39180.1 - 0.069 12.8 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Triple gene block 3 Transp_cyt_pur PF02133.15 OAG39183.1 - 1.6e-75 254.6 32.7 1.9e-75 254.3 32.7 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Amidase PF01425.21 OAG39184.1 - 2.6e-71 240.9 0.0 3.3e-71 240.6 0.0 1.1 1 0 0 1 1 1 1 Amidase Isochorismatase PF00857.20 OAG39184.1 - 5.3e-36 124.4 0.0 3.4e-35 121.8 0.0 2.1 2 0 0 2 2 2 1 Isochorismatase family Ovate PF04844.13 OAG39184.1 - 0.056 13.4 0.1 0.14 12.1 0.1 1.6 1 0 0 1 1 1 0 Transcriptional repressor, ovate Zn_clus PF00172.18 OAG39185.1 - 0.00052 20.1 8.0 0.00079 19.5 8.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAM199X PF15814.5 OAG39185.1 - 0.019 14.1 0.9 0.022 13.8 0.9 1.1 1 0 0 1 1 1 0 Protein family FAM199X Fungal_trans PF04082.18 OAG39186.1 - 9.7e-24 83.8 0.1 1.5e-23 83.2 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Beta-lactamase PF00144.24 OAG39187.1 - 2.6e-66 224.1 0.1 3.2e-66 223.8 0.1 1.0 1 0 0 1 1 1 1 Beta-lactamase Fungal_trans_2 PF11951.8 OAG39188.1 - 0.012 14.4 0.3 0.012 14.4 0.3 2.0 2 0 0 2 2 2 0 Fungal specific transcription factor domain Atg8 PF02991.16 OAG39189.1 - 9.7e-51 170.3 0.2 1.1e-50 170.1 0.2 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 OAG39189.1 - 3.7e-06 27.2 0.0 4.5e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Coprogen_oxidas PF01218.18 OAG39190.1 - 7.8e-136 451.6 0.0 9.4e-136 451.3 0.0 1.1 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase Cu-oxidase_3 PF07732.15 OAG39191.1 - 3.5e-42 143.2 14.7 6.9e-41 139.0 2.8 3.8 4 0 0 4 4 4 3 Multicopper oxidase Cu-oxidase PF00394.22 OAG39191.1 - 2.6e-38 131.6 0.0 4.9e-35 121.0 0.0 2.5 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 OAG39191.1 - 1e-37 128.9 13.6 2.4e-32 111.5 2.7 4.2 3 1 0 3 3 3 3 Multicopper oxidase Atg29_N PF18388.1 OAG39192.1 - 2e-27 94.8 1.0 4e-27 93.8 1.0 1.5 1 0 0 1 1 1 1 Atg29 N-terminal domain Prok-RING_2 PF14445.6 OAG39193.1 - 0.86 9.8 4.9 0.62 10.3 1.1 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 2 Glyco_hydro_16 PF00722.21 OAG39194.1 - 3e-06 26.8 0.0 4.4e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.15 OAG39194.1 - 0.071 11.5 0.0 0.11 10.9 0.0 1.1 1 0 0 1 1 1 0 Beta-glucan synthesis-associated protein (SKN1) Ferritin_2 PF13668.6 OAG39195.1 - 8.4e-18 64.9 0.0 1.7e-17 63.9 0.0 1.4 1 0 0 1 1 1 1 Ferritin-like domain ATF7IP_BD PF16788.5 OAG39196.1 - 1 9.4 3.0 2.2 8.4 3.0 1.5 1 0 0 1 1 1 0 ATF-interacting protein binding domain Tmemb_9 PF05434.11 OAG39198.1 - 0.0078 16.1 0.1 0.0078 16.1 0.1 1.7 2 0 0 2 2 2 1 TMEM9 RNA_capsid PF03035.14 OAG39198.1 - 0.013 15.5 0.3 0.021 14.9 0.3 1.4 1 0 0 1 1 1 0 Calicivirus putative RNA polymerase/capsid protein AAL_decarboxy PF03306.13 OAG39200.1 - 5.4e-66 222.1 0.1 6.4e-66 221.8 0.1 1.1 1 0 0 1 1 1 1 Alpha-acetolactate decarboxylase TPP_enzyme_N PF02776.18 OAG39201.1 - 2.9e-43 147.4 0.7 1.8e-42 144.9 1.8 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 OAG39201.1 - 9.7e-32 109.9 1.1 4.2e-31 107.8 0.1 2.3 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 OAG39201.1 - 2.1e-21 76.1 0.0 4.2e-21 75.1 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain DUF1194 PF06707.11 OAG39201.1 - 0.055 12.7 0.0 0.099 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1194) Transferase PF02458.15 OAG39204.1 - 1.5e-12 47.0 0.0 2.2e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 Transferase family Asp PF00026.23 OAG39205.1 - 2e-32 112.9 0.0 4.6e-32 111.7 0.0 1.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OAG39205.1 - 0.0012 19.1 0.2 0.41 10.9 0.2 2.5 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 OAG39205.1 - 0.0022 18.6 1.7 1.1 9.9 0.1 2.9 3 0 0 3 3 3 2 Aspartyl protease TAXi_C PF14541.6 OAG39205.1 - 0.011 15.5 0.1 0.035 13.9 0.0 1.8 1 1 1 2 2 2 0 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 OAG39205.1 - 0.021 15.4 0.5 3.8 8.1 0.0 2.8 3 0 0 3 3 3 0 gag-polyprotein putative aspartyl protease DXP_synthase_N PF13292.6 OAG39205.1 - 0.78 8.9 1.8 0.56 9.4 0.2 1.4 2 0 0 2 2 2 0 1-deoxy-D-xylulose-5-phosphate synthase Mob1_phocein PF03637.17 OAG39206.1 - 6e-46 156.6 0.0 1.8e-45 155.0 0.0 1.7 1 1 0 1 1 1 1 Mob1/phocein family Leo1 PF04004.13 OAG39207.1 - 6e-33 114.0 0.1 6e-33 114.0 0.1 2.0 2 0 0 2 2 2 1 Leo1-like protein BAH PF01426.18 OAG39208.1 - 7.8e-18 64.5 0.0 1.5e-17 63.6 0.0 1.5 1 0 0 1 1 1 1 BAH domain zf-HC5HC2H_2 PF13832.6 OAG39208.1 - 3.5e-16 59.3 0.0 3.5e-16 59.3 0.0 3.7 3 1 0 3 3 3 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 OAG39208.1 - 1.2e-13 51.1 0.1 1.2e-13 51.1 0.1 4.2 4 0 0 4 4 4 2 PHD-like zinc-binding domain PHD PF00628.29 OAG39208.1 - 9.5e-12 44.6 41.7 6.2e-07 29.2 5.0 5.7 6 0 0 6 6 6 2 PHD-finger PHD_2 PF13831.6 OAG39208.1 - 4.3e-09 35.8 3.3 4.3e-09 35.8 3.3 4.2 5 0 0 5 5 5 1 PHD-finger C1_1 PF00130.22 OAG39208.1 - 0.00066 19.5 3.8 0.00066 19.5 3.8 6.3 6 1 1 7 7 7 2 Phorbol esters/diacylglycerol binding domain (C1 domain) DNA_primase_lrg PF04104.14 OAG39208.1 - 0.041 13.3 0.7 0.11 11.9 0.7 1.6 1 0 0 1 1 1 0 Eukaryotic and archaeal DNA primase, large subunit Myb_DNA-binding PF00249.31 OAG39208.1 - 0.058 13.6 0.1 0.23 11.7 0.1 2.1 2 0 0 2 2 2 0 Myb-like DNA-binding domain LsmAD PF06741.13 OAG39208.1 - 0.08 13.5 0.2 0.08 13.5 0.2 2.5 3 0 0 3 3 3 0 LsmAD domain Actin_micro PF17003.5 OAG39208.1 - 0.33 10.1 2.3 9.8 5.2 0.1 2.2 2 0 0 2 2 2 0 Putative actin-like family DEAD PF00270.29 OAG39209.1 - 5.6e-15 55.5 0.0 1.4e-14 54.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAG39209.1 - 1.8e-06 28.3 0.0 4.7e-06 26.9 0.0 1.8 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG39209.1 - 4.3e-06 26.8 0.0 7.1e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF4332 PF14229.6 OAG39209.1 - 0.0032 17.7 0.2 0.0096 16.2 0.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4332) HHH_5 PF14520.6 OAG39209.1 - 0.014 16.0 0.0 0.068 13.8 0.0 2.2 2 0 0 2 2 2 0 Helix-hairpin-helix domain FMN_red PF03358.15 OAG39210.1 - 1.3e-08 34.8 0.0 1.6e-08 34.4 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_1 PF00258.25 OAG39210.1 - 0.00024 21.3 0.3 0.00064 19.9 0.3 1.8 1 1 0 1 1 1 1 Flavodoxin Flavodoxin_2 PF02525.17 OAG39210.1 - 0.016 14.9 0.0 0.02 14.6 0.0 1.1 1 0 0 1 1 1 0 Flavodoxin-like fold Flavodoxin_5 PF12724.7 OAG39210.1 - 0.19 12.0 0.1 4 7.7 0.0 2.1 1 1 1 2 2 2 0 Flavodoxin domain Zn_clus PF00172.18 OAG39211.1 - 3.2e-08 33.6 10.6 6.9e-08 32.5 10.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain APH PF01636.23 OAG39212.1 - 4.9e-38 131.4 0.0 7.1e-38 130.9 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 OAG39212.1 - 3.9e-05 23.3 0.0 0.077 12.6 0.1 2.3 2 0 0 2 2 2 2 RIO1 family EcKinase PF02958.20 OAG39212.1 - 8.7e-05 22.0 0.0 0.00015 21.2 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase Pkinase PF00069.25 OAG39212.1 - 0.095 12.0 0.0 5.6 6.2 0.0 2.2 2 0 0 2 2 2 0 Protein kinase domain AMP-binding PF00501.28 OAG39213.1 - 2.3e-59 201.1 0.0 3e-59 200.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG39213.1 - 2.2e-12 47.8 0.4 6.6e-12 46.2 0.1 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ATXN-1_C PF12547.8 OAG39213.1 - 0.11 12.9 0.5 0.11 12.9 0.5 1.8 2 0 0 2 2 2 0 Capicua transcriptional repressor modulator MaoC_dehydratas PF01575.19 OAG39214.1 - 1.7e-27 95.4 0.0 5.5e-27 93.8 0.0 1.8 2 0 0 2 2 2 1 MaoC like domain MaoC_dehydrat_N PF13452.6 OAG39214.1 - 6.1e-10 39.3 0.1 0.00086 19.4 0.1 2.3 2 0 0 2 2 2 2 N-terminal half of MaoC dehydratase Cupin_7 PF12973.7 OAG39214.1 - 0.12 12.3 0.2 0.22 11.5 0.2 1.4 1 0 0 1 1 1 0 ChrR Cupin-like domain ECH_1 PF00378.20 OAG39215.1 - 1.5e-36 126.0 0.0 1.8e-36 125.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAG39215.1 - 2e-16 60.4 0.0 2.5e-16 60.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase DEAD PF00270.29 OAG39216.1 - 1.6e-52 177.9 0.0 3.1e-52 176.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAG39216.1 - 2.8e-33 114.6 0.2 9.1e-29 100.0 0.0 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 OAG39216.1 - 1.6e-09 38.0 0.0 3.4e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 OAG39216.1 - 1.1e-06 28.1 0.1 2.9e-05 23.4 0.1 2.2 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase AAA_30 PF13604.6 OAG39216.1 - 0.0041 16.9 0.0 0.0088 15.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain Helicase_RecD PF05127.14 OAG39216.1 - 0.0056 16.6 0.2 0.014 15.2 0.0 1.7 2 0 0 2 2 2 1 Helicase CMS1 PF14617.6 OAG39216.1 - 0.15 11.4 3.3 1.5 8.1 0.0 2.5 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit Rft-1 PF04506.13 OAG39217.1 - 3.5e-113 379.1 10.9 1.7e-111 373.5 10.9 2.0 1 1 0 1 1 1 1 Rft protein Proteasome PF00227.26 OAG39218.1 - 7.6e-45 152.7 0.1 1.1e-44 152.3 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 OAG39218.1 - 3.2e-15 55.2 3.0 3.2e-15 55.2 3.0 1.8 2 0 0 2 2 2 1 Proteasome beta subunits C terminal Sugar_tr PF00083.24 OAG39219.1 - 1.2e-79 268.3 24.4 1.4e-79 268.1 24.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG39219.1 - 7.8e-33 113.9 47.4 2.5e-25 89.2 24.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily NUP214 PF16755.5 OAG39220.1 - 2.2e-10 40.3 0.0 7.7e-10 38.5 0.0 1.8 1 1 0 1 1 1 1 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 ANAPC4_WD40 PF12894.7 OAG39220.1 - 0.00076 19.7 0.0 0.042 14.1 0.0 2.6 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain KH_1 PF00013.29 OAG39221.1 - 1.5e-42 143.2 3.2 4.9e-18 64.7 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 OAG39221.1 - 1.2e-10 41.0 1.0 0.0099 15.7 0.2 3.2 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 OAG39221.1 - 3e-05 24.0 6.7 0.22 11.6 0.1 3.3 3 0 0 3 3 3 3 NusA-like KH domain MOEP19 PF16005.5 OAG39221.1 - 0.0001 22.2 0.0 0.014 15.4 0.0 2.3 2 0 0 2 2 2 2 KH-like RNA-binding domain KH_4 PF13083.6 OAG39221.1 - 0.00018 21.3 0.0 0.79 9.6 0.0 3.2 3 0 0 3 3 3 2 KH domain Meth_synt_2 PF01717.18 OAG39222.1 - 8.1e-09 35.2 0.0 2.9e-06 26.8 0.0 2.9 2 1 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Oberon_cc PF16312.5 OAG39222.1 - 0.017 15.0 0.7 0.15 12.0 0.0 2.5 3 0 0 3 3 3 0 Coiled-coil region of Oberon Sugar_tr PF00083.24 OAG39223.1 - 1.7e-72 244.7 26.7 2.7e-58 197.9 17.3 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 OAG39223.1 - 1.7e-21 76.6 26.8 6.6e-20 71.3 21.6 3.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Ost4 PF10215.9 OAG39223.1 - 0.079 12.8 0.6 0.82 9.5 0.1 2.9 2 0 0 2 2 2 0 Oligosaccaryltransferase adh_short_C2 PF13561.6 OAG39224.1 - 7.4e-56 189.3 2.2 1.5e-54 185.0 2.2 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG39224.1 - 1.7e-47 161.4 3.4 2.3e-47 161.0 3.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG39224.1 - 0.001 19.0 0.7 0.0032 17.4 0.7 1.7 1 1 1 2 2 2 1 KR domain Epimerase PF01370.21 OAG39224.1 - 0.024 14.1 0.3 0.24 10.8 0.3 2.2 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family UPF0146 PF03686.13 OAG39224.1 - 0.093 12.6 0.1 0.18 11.6 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) 3HCDH_N PF02737.18 OAG39224.1 - 0.1 12.5 0.3 0.1 12.5 0.3 2.2 2 1 1 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DLH PF01738.18 OAG39225.1 - 5.6e-22 78.4 0.0 6.6e-22 78.1 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Gpr1_Fun34_YaaH PF01184.19 OAG39226.1 - 2.4e-31 109.0 20.4 3.4e-31 108.5 20.4 1.2 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF2909 PF11137.8 OAG39227.1 - 0.18 11.8 0.8 0.38 10.7 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2909) DSPc PF00782.20 OAG39230.1 - 2.9e-09 36.8 0.0 5.1e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 OAG39230.1 - 0.00022 20.9 0.0 0.00034 20.3 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 OAG39230.1 - 0.02 15.0 0.0 0.04 14.0 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 OAG39230.1 - 0.069 13.1 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family PTEN_C2 PF10409.9 OAG39230.1 - 0.11 12.2 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 C2 domain of PTEN tumour-suppressor protein MFS_1 PF07690.16 OAG39231.1 - 9.5e-27 93.8 56.0 1.7e-19 70.0 43.8 3.3 2 1 1 3 3 3 2 Major Facilitator Superfamily MMM1 PF10296.9 OAG39232.1 - 1.5e-129 431.9 0.0 1.8e-129 431.5 0.0 1.1 1 0 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 DUF2683 PF10884.8 OAG39232.1 - 0.017 15.4 0.0 0.039 14.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2683) ARD PF03079.14 OAG39234.1 - 2.4e-45 154.5 0.6 2.9e-45 154.2 0.6 1.1 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 OAG39234.1 - 1.2e-08 34.5 0.0 2.1e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 OAG39234.1 - 1.9e-05 24.6 0.0 3.3e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain adh_short PF00106.25 OAG39235.1 - 1e-28 100.1 0.0 1.7e-28 99.4 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG39235.1 - 4.8e-19 68.8 0.0 6.5e-19 68.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG39235.1 - 1.7e-08 34.6 0.0 2.8e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG39235.1 - 0.00015 21.3 0.0 0.00032 20.2 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 OAG39235.1 - 0.032 13.4 0.0 0.046 12.8 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 OAG39235.1 - 0.033 13.3 0.0 0.064 12.4 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain DapB_N PF01113.20 OAG39235.1 - 0.067 13.3 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NmrA PF05368.13 OAG39235.1 - 0.099 12.2 1.3 0.12 11.9 0.0 1.7 2 0 0 2 2 2 0 NmrA-like family Dicty_REP PF05086.12 OAG39235.1 - 0.5 8.3 1.8 0.67 7.9 1.8 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein BRE1 PF08647.11 OAG39236.1 - 2.8e-25 88.2 10.9 2.8e-25 88.2 10.9 6.8 5 1 0 6 6 6 1 BRE1 E3 ubiquitin ligase zf-C3HC4_2 PF13923.6 OAG39236.1 - 1.7e-09 37.3 8.1 3.1e-09 36.5 8.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OAG39236.1 - 1.1e-08 34.8 7.0 2e-08 34.0 7.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAG39236.1 - 1.8e-07 30.9 10.7 3.2e-07 30.1 10.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) APG6_N PF17675.1 OAG39236.1 - 5e-07 30.3 98.4 0.00074 20.0 2.7 7.1 2 1 5 7 7 7 3 Apg6 coiled-coil region zf-RING_UBOX PF13445.6 OAG39236.1 - 6.2e-07 29.3 5.1 1.4e-06 28.2 5.1 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 OAG39236.1 - 5.6e-06 26.6 6.9 9.6e-06 25.8 6.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 OAG39236.1 - 1e-05 25.4 9.8 1.7e-05 24.7 9.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 OAG39236.1 - 1.9e-05 24.4 6.8 3.3e-05 23.7 6.8 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 DUF1272 PF06906.11 OAG39236.1 - 0.00034 20.6 5.5 0.00071 19.6 5.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1272) KxDL PF10241.9 OAG39236.1 - 0.0014 18.8 8.4 0.0014 18.8 8.4 7.7 6 3 2 9 9 8 1 Uncharacterized conserved protein zf-C3HC4_4 PF15227.6 OAG39236.1 - 0.0022 18.1 6.0 0.0042 17.2 6.0 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING ADIP PF11559.8 OAG39236.1 - 0.0069 16.5 7.1 0.0069 16.5 7.1 7.1 5 2 1 6 6 6 3 Afadin- and alpha -actinin-Binding DZR PF12773.7 OAG39236.1 - 0.0076 16.2 6.8 0.015 15.4 6.8 1.4 1 0 0 1 1 1 1 Double zinc ribbon zf-RING_10 PF16685.5 OAG39236.1 - 0.017 15.3 4.4 0.1 12.8 5.2 2.0 2 0 0 2 2 1 0 zinc RING finger of MSL2 zf-RING_4 PF14570.6 OAG39236.1 - 0.049 13.4 5.5 0.098 12.5 5.3 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-ribbon_3 PF13248.6 OAG39236.1 - 0.19 11.2 3.4 0.43 10.1 0.9 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-rbx1 PF12678.7 OAG39236.1 - 0.25 11.7 8.0 0.099 12.9 4.9 2.0 2 0 0 2 2 1 0 RING-H2 zinc finger domain ATG16 PF08614.11 OAG39236.1 - 1.6 8.9 100.1 0.015 15.6 29.1 5.9 2 1 3 6 6 6 0 Autophagy protein 16 (ATG16) FYVE PF01363.21 OAG39236.1 - 7.3 6.8 9.9 7.6 6.7 5.1 2.5 1 1 1 2 2 2 0 FYVE zinc finger CENP-F_leu_zip PF10473.9 OAG39236.1 - 9 6.3 79.4 1.5 8.8 25.6 6.6 3 1 3 6 6 6 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Myb_DNA-bind_7 PF15963.5 OAG39237.1 - 4.5e-19 68.1 0.0 1.9e-18 66.1 0.0 2.2 1 0 0 1 1 1 1 Myb DNA-binding like UreF PF01730.16 OAG39238.1 - 6.2e-23 81.8 0.3 9e-23 81.3 0.3 1.2 1 0 0 1 1 1 1 UreF ABC1 PF03109.16 OAG39239.1 - 1.8e-33 115.2 0.0 3.3e-33 114.4 0.0 1.4 1 0 0 1 1 1 1 ABC1 family NAD_binding_4 PF07993.12 OAG39240.1 - 0.00046 19.4 0.0 0.064 12.4 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein Epimerase PF01370.21 OAG39240.1 - 0.00052 19.6 0.0 0.00075 19.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family MFS_2 PF13347.6 OAG39241.1 - 4.1e-12 45.4 4.4 4.1e-12 45.4 4.4 2.6 3 0 0 3 3 3 1 MFS/sugar transport protein MFS_1 PF07690.16 OAG39241.1 - 5.7e-09 35.4 14.3 5.7e-09 35.4 14.3 2.9 2 1 0 3 3 3 1 Major Facilitator Superfamily PUCC PF03209.15 OAG39241.1 - 0.001 18.1 1.9 0.002 17.2 1.1 1.8 2 0 0 2 2 2 1 PUCC protein BT1 PF03092.16 OAG39241.1 - 0.026 12.8 2.5 1.1 7.4 0.1 2.3 2 0 0 2 2 2 0 BT1 family DUF1146 PF06612.11 OAG39241.1 - 0.23 11.5 3.2 0.27 11.3 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1146) YfzA PF14118.6 OAG39241.1 - 1.8 9.0 4.9 1.5 9.2 0.1 2.9 3 0 0 3 3 3 0 YfzA-like protein Ligase_CoA PF00549.19 OAG39242.1 - 3e-23 82.3 0.3 4.9e-23 81.6 0.3 1.3 1 0 0 1 1 1 1 CoA-ligase CoA_binding PF02629.19 OAG39242.1 - 8.9e-20 71.2 4.2 1.3e-19 70.6 0.7 2.4 2 0 0 2 2 2 1 CoA binding domain Succ_CoA_lig PF13607.6 OAG39242.1 - 7.9e-08 32.2 0.1 1.4e-07 31.4 0.1 1.4 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 OAG39242.1 - 0.0031 18.0 0.1 0.0075 16.7 0.1 1.7 1 0 0 1 1 1 1 CoA binding domain Sugar_tr PF00083.24 OAG39243.1 - 3.7e-106 355.7 30.5 4.2e-106 355.5 30.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG39243.1 - 2.3e-33 115.6 24.8 2.3e-33 115.6 24.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 OAG39243.1 - 3.9e-06 25.6 4.6 3.9e-06 25.6 4.6 2.4 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) V-SNARE PF05008.15 OAG39243.1 - 0.037 14.4 0.3 0.066 13.6 0.3 1.4 1 0 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus Sensor_TM1 PF13755.6 OAG39243.1 - 0.4 10.4 0.1 0.4 10.4 0.1 2.6 3 0 0 3 3 3 0 Sensor N-terminal transmembrane domain Fungal_trans_2 PF11951.8 OAG39244.1 - 4.8e-09 35.5 0.0 6.6e-09 35.1 0.0 1.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain Holin_2-3 PF13272.6 OAG39244.1 - 0.48 10.7 1.5 3.2 8.1 0.1 2.5 2 0 0 2 2 2 0 Putative 2/3 transmembrane domain holin p450 PF00067.22 OAG39245.1 - 1.6e-55 188.7 0.0 2.1e-55 188.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 APG17 PF04108.12 OAG39245.1 - 0.017 14.3 0.0 0.024 13.8 0.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg17 Radical_SAM_C PF16199.5 OAG39246.1 - 2e-32 111.0 0.0 3.9e-32 110.1 0.0 1.5 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 OAG39246.1 - 2.5e-19 70.3 0.0 6.3e-19 69.0 0.0 1.6 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 OAG39246.1 - 9.9e-12 45.1 0.0 2.2e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OAG39246.1 - 9.1e-09 35.3 0.6 1.3e-06 28.4 0.0 3.4 3 1 0 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OAG39246.1 - 0.0055 17.1 0.0 0.012 16.0 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain TP_methylase PF00590.20 OAG39247.1 - 5.5e-49 167.0 0.4 9.2e-49 166.3 0.4 1.4 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.6 OAG39247.1 - 2.4e-12 47.2 0.0 4.5e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 OAG39247.1 - 5.7e-11 41.9 0.1 1.4e-07 31.0 0.0 3.5 3 0 0 3 3 3 2 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 OAG39247.1 - 8.2e-11 41.2 0.2 2.2e-10 39.8 0.2 1.8 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central adh_short PF00106.25 OAG39248.1 - 1.8e-32 112.4 0.0 3.3e-32 111.5 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG39248.1 - 1.1e-22 80.7 0.0 4.8e-22 78.7 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Glyco_transf_90 PF05686.12 OAG39248.1 - 2.1e-18 66.5 2.3 1.2e-14 54.1 0.5 2.9 2 1 0 2 2 2 2 Glycosyl transferase family 90 KR PF08659.10 OAG39248.1 - 7.8e-06 25.9 0.0 0.093 12.6 0.0 2.7 2 0 0 2 2 2 2 KR domain MHC2-interact PF09307.10 OAG39248.1 - 0.11 12.5 0.4 0.24 11.4 0.4 1.5 1 0 0 1 1 1 0 CLIP, MHC2 interacting HEAT PF02985.22 OAG39249.1 - 1.2e-37 124.6 16.0 0.014 15.6 0.1 13.1 14 0 0 14 14 14 10 HEAT repeat HEAT_2 PF13646.6 OAG39249.1 - 9.9e-37 125.2 7.2 1.8e-10 41.1 0.0 8.1 4 2 4 8 8 8 7 HEAT repeats Vac14_Fab1_bd PF12755.7 OAG39249.1 - 4.6e-14 52.8 3.3 0.00022 21.8 0.1 7.2 6 2 3 9 9 9 3 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 OAG39249.1 - 1.6e-12 47.6 10.6 0.0043 17.5 0.0 8.3 6 3 3 9 9 9 2 HEAT-like repeat Cnd1 PF12717.7 OAG39249.1 - 1.4e-10 41.5 10.0 0.0046 17.0 0.1 6.1 5 1 1 7 7 7 3 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 OAG39249.1 - 4.3e-07 29.7 1.7 0.087 12.4 0.1 4.4 3 1 1 4 4 4 2 CLASP N terminal RTP1_C1 PF10363.9 OAG39249.1 - 6e-07 29.6 4.5 0.19 11.9 0.1 4.6 4 1 1 5 5 5 3 Required for nuclear transport of RNA pol II C-terminus 1 Adaptin_N PF01602.20 OAG39249.1 - 2.4e-05 23.1 10.6 0.091 11.3 0.1 4.6 2 2 0 4 4 4 2 Adaptin N terminal region TetR_C_16 PF17920.1 OAG39249.1 - 0.0081 16.4 0.1 9.9 6.4 0.0 3.4 1 1 1 2 2 2 1 Tetracyclin repressor-like, C-terminal domain Proteasom_PSMB PF10508.9 OAG39249.1 - 0.09 11.3 2.6 0.46 8.9 0.0 2.5 2 1 0 2 2 2 0 Proteasome non-ATPase 26S subunit IFRD PF05004.13 OAG39249.1 - 0.097 11.8 0.5 1.1 8.3 0.1 2.9 2 1 0 2 2 2 0 Interferon-related developmental regulator (IFRD) M11L PF11099.8 OAG39249.1 - 0.15 12.3 0.3 17 5.7 0.0 3.3 2 2 1 4 4 4 0 Apoptosis regulator M11L like Arm PF00514.23 OAG39249.1 - 0.76 9.9 5.0 5.3 7.2 0.0 4.0 6 0 0 6 6 5 0 Armadillo/beta-catenin-like repeat API5 PF05918.11 OAG39249.1 - 2.3 6.9 9.0 0.57 8.9 0.2 3.7 5 0 0 5 5 5 0 Apoptosis inhibitory protein 5 (API5) tRNA_synthFbeta PF17759.1 OAG39250.1 - 9e-48 162.5 0.0 1.5e-47 161.9 0.0 1.3 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 OAG39250.1 - 8e-32 109.3 0.3 7.5e-30 103.0 0.1 2.6 2 0 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 OAG39250.1 - 7e-26 90.9 0.1 1.2e-25 90.2 0.1 1.4 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 OAG39250.1 - 2.6e-18 66.1 0.0 5.9e-16 58.5 0.0 2.6 2 0 0 2 2 2 2 tRNA synthetase B5 domain Polysacc_deac_3 PF15421.6 OAG39250.1 - 0.068 11.7 0.0 0.12 10.9 0.0 1.2 1 0 0 1 1 1 0 Putative polysaccharide deacetylase Ribosomal_S3_C PF00189.20 OAG39251.1 - 1.3e-24 86.5 0.1 6.5e-24 84.3 0.1 2.1 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 OAG39251.1 - 8.9e-12 44.7 0.1 1.5e-11 43.9 0.1 1.4 1 0 0 1 1 1 1 KH domain CoA_binding_2 PF13380.6 OAG39251.1 - 0.11 13.0 0.9 0.43 11.1 0.2 2.1 3 0 0 3 3 3 0 CoA binding domain UN_NPL4 PF11543.8 OAG39251.1 - 0.13 12.7 0.0 0.25 11.8 0.0 1.4 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Coilin_N PF15862.5 OAG39251.1 - 0.2 11.4 0.0 0.41 10.5 0.0 1.4 1 0 0 1 1 1 0 Coilin N-terminus DEAD PF00270.29 OAG39252.1 - 2.5e-43 147.9 0.0 2.9e-42 144.4 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAG39252.1 - 5.5e-25 87.9 0.0 1.9e-24 86.1 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AA_permease_2 PF13520.6 OAG39253.1 - 5.6e-51 173.7 56.6 6.9e-51 173.4 56.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAG39253.1 - 6.7e-14 51.3 45.7 1e-13 50.7 45.7 1.2 1 0 0 1 1 1 1 Amino acid permease IF2_assoc PF08364.11 OAG39253.1 - 0.095 13.0 0.2 0.17 12.2 0.2 1.3 1 0 0 1 1 1 0 Bacterial translation initiation factor IF-2 associated region Epiglycanin_C PF14654.6 OAG39253.1 - 0.24 11.5 2.6 0.22 11.6 0.4 2.1 2 0 0 2 2 2 0 Mucin, catalytic, TM and cytoplasmic tail region T_cell_tran_alt PF15128.6 OAG39254.1 - 0.026 14.3 0.0 0.056 13.3 0.0 1.5 1 0 0 1 1 1 0 T-cell leukemia translocation-altered DUF4407 PF14362.6 OAG39255.1 - 0.21 10.9 0.9 0.27 10.6 0.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF5401 PF17380.2 OAG39255.1 - 2.7 5.9 9.0 3.8 5.5 9.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) Glyoxal_oxid_N PF07250.11 OAG39256.1 - 1.8e-45 155.1 0.1 9.2e-45 152.7 0.0 2.2 2 1 0 2 2 2 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 OAG39256.1 - 8.5e-16 58.0 0.1 1.6e-15 57.2 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_3 PF13415.6 OAG39256.1 - 0.0038 17.5 0.1 0.11 12.8 0.1 3.3 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_4 PF13418.6 OAG39256.1 - 0.049 13.7 0.8 49 4.0 0.0 4.1 4 0 0 4 4 4 0 Galactose oxidase, central domain DNA_pol3_chi PF04364.13 OAG39256.1 - 0.11 12.7 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase III chi subunit, HolC DUF5122 PF17164.4 OAG39256.1 - 0.71 10.2 4.1 2.1 8.7 0.1 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF5122) beta-propeller HEAT PF02985.22 OAG39258.1 - 0.025 14.8 1.6 17 6.0 0.0 3.9 3 0 0 3 3 3 0 HEAT repeat adh_short_C2 PF13561.6 OAG39259.1 - 2.4e-43 148.3 2.5 3e-43 148.0 2.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG39259.1 - 5.3e-34 117.4 4.0 7.4e-34 116.9 4.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG39259.1 - 2e-09 37.6 1.7 3e-09 37.1 1.7 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG39259.1 - 0.00012 21.7 0.3 0.002 17.6 0.3 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 OAG39259.1 - 0.0014 18.1 0.0 0.0029 17.0 0.0 1.5 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) GDP_Man_Dehyd PF16363.5 OAG39259.1 - 0.033 13.6 0.1 1.6 8.1 0.0 2.1 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 OAG39259.1 - 0.049 12.7 0.6 0.07 12.2 0.6 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.8 OAG39259.1 - 0.17 11.7 1.9 0.38 10.5 1.9 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase SnoaL_2 PF12680.7 OAG39260.1 - 2.5e-05 24.8 0.2 3.1e-05 24.5 0.2 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 OAG39260.1 - 0.031 14.1 0.5 0.16 11.8 0.5 1.9 1 1 0 1 1 1 0 SnoaL-like polyketide cyclase Pyr_redox_2 PF07992.14 OAG39261.1 - 3.7e-33 115.0 0.0 8.5e-31 107.3 0.0 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAG39261.1 - 4.4e-12 46.4 0.0 2.5e-08 34.4 0.0 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG39261.1 - 0.00017 21.8 0.0 0.25 11.6 0.0 2.8 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 OAG39261.1 - 0.0034 16.7 0.1 0.43 9.8 0.0 2.4 2 0 0 2 2 2 2 FAD binding domain FAD_binding_2 PF00890.24 OAG39261.1 - 0.035 13.2 0.0 0.79 8.7 0.0 2.5 3 0 0 3 3 3 0 FAD binding domain FHA PF00498.26 OAG39262.1 - 1.3e-16 60.7 0.3 2.5e-16 59.8 0.0 1.7 2 0 0 2 2 1 1 FHA domain Yop-YscD_cpl PF16697.5 OAG39262.1 - 0.00016 21.9 0.0 0.00043 20.5 0.0 1.7 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Spc29 PF17082.5 OAG39262.1 - 0.00075 19.4 2.5 0.00075 19.4 2.5 1.9 1 1 0 1 1 1 1 Spindle Pole Component 29 YhfZ_C PF14503.6 OAG39262.1 - 0.0047 16.5 0.0 0.01 15.4 0.0 1.4 1 0 0 1 1 1 1 YhfZ C-terminal domain OmpH PF03938.14 OAG39262.1 - 0.017 15.4 7.3 0.017 15.4 7.3 2.6 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) DUF2937 PF11157.8 OAG39262.1 - 0.68 9.6 7.9 0.28 10.9 4.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) Fib_alpha PF08702.10 OAG39262.1 - 0.93 9.7 10.1 0.047 13.9 2.4 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Tropomyosin_1 PF12718.7 OAG39262.1 - 1.5 9.0 31.9 0.068 13.3 13.0 2.7 2 1 1 3 3 2 0 Tropomyosin like XhlA PF10779.9 OAG39262.1 - 2.9 8.2 7.5 0.69 10.2 0.5 2.5 2 0 0 2 2 2 0 Haemolysin XhlA Jnk-SapK_ap_N PF09744.9 OAG39262.1 - 4 7.7 25.9 0.56 10.4 12.1 2.4 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 TolA_bind_tri PF16331.5 OAG39262.1 - 7 6.8 18.4 0.45 10.6 3.6 2.9 3 0 0 3 3 3 0 TolA binding protein trimerisation Syntaxin-5_N PF11416.8 OAG39263.1 - 3.2e-10 38.9 1.5 3.2e-10 38.9 1.5 2.0 2 0 0 2 2 2 1 Syntaxin-5 N-terminal, Sly1p-binding domain SNARE PF05739.19 OAG39263.1 - 1e-09 38.3 0.1 1e-09 38.3 0.1 1.7 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.25 OAG39263.1 - 2.3e-05 24.2 6.0 7.8e-05 22.4 0.1 2.9 2 1 1 3 3 3 1 Syntaxin KxDL PF10241.9 OAG39263.1 - 0.00077 19.7 5.2 0.11 12.8 0.1 3.3 4 0 0 4 4 4 2 Uncharacterized conserved protein NPV_P10 PF05531.12 OAG39263.1 - 0.0063 16.9 4.9 0.82 10.2 0.4 3.5 3 0 0 3 3 3 1 Nucleopolyhedrovirus P10 protein Syntaxin-18_N PF10496.9 OAG39263.1 - 0.02 15.1 2.5 0.073 13.3 0.1 2.7 2 1 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus DUF16 PF01519.16 OAG39263.1 - 0.88 10.1 4.7 0.4 11.2 0.2 2.4 2 1 0 2 2 2 0 Protein of unknown function DUF16 Sas10_Utp3 PF04000.15 OAG39266.1 - 7.4e-17 61.7 1.1 7.4e-17 61.7 1.1 2.5 3 0 0 3 3 3 1 Sas10/Utp3/C1D family SRP-alpha_N PF04086.13 OAG39266.1 - 2.1 8.2 22.1 2.8 7.8 22.1 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal ApbA_C PF08546.11 OAG39267.1 - 3e-31 108.2 0.0 4.4e-31 107.7 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 OAG39267.1 - 4e-23 81.8 0.0 4.6e-22 78.3 0.0 2.2 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA DUF3433 PF11915.8 OAG39272.1 - 6.3e-31 106.7 13.1 1.7e-23 82.9 2.4 3.8 5 0 0 5 5 5 2 Protein of unknown function (DUF3433) Virul_fac_BrkB PF03631.15 OAG39272.1 - 0.12 12.0 38.2 0.17 11.4 3.5 4.1 4 0 0 4 4 4 0 Virulence factor BrkB DUF3377 PF11857.8 OAG39272.1 - 2.6 8.0 4.9 16 5.5 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3377) COesterase PF00135.28 OAG39273.1 - 3.8e-08 32.7 0.1 7.2e-08 31.7 0.1 1.3 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAG39273.1 - 1.9e-07 31.2 0.0 2.8e-07 30.6 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 OAG39273.1 - 0.0007 18.6 0.0 0.0085 15.0 0.0 2.0 2 0 0 2 2 2 1 Steryl acetyl hydrolase Cyclase PF04199.13 OAG39274.1 - 2.1e-18 66.8 0.1 3e-18 66.4 0.1 1.2 1 0 0 1 1 1 1 Putative cyclase LPD22 PF18834.1 OAG39274.1 - 0.066 13.4 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Large polyvalent protein associated domain 22 TRI12 PF06609.13 OAG39275.1 - 2.1e-42 145.4 20.9 2.6e-42 145.1 20.9 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG39275.1 - 3.2e-10 39.5 42.3 3.2e-10 39.5 42.3 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF3278 PF11683.8 OAG39275.1 - 0.013 15.6 0.2 1.2 9.2 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3278) LapA_dom PF06305.11 OAG39275.1 - 1.1 9.1 3.7 2.5 8.0 0.5 3.2 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain DUF3087 PF11286.8 OAG39275.1 - 2.2 7.7 3.8 4.4 6.7 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3087) ADH_zinc_N PF00107.26 OAG39276.1 - 2.2e-21 76.2 0.1 4.1e-21 75.3 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAG39276.1 - 6.6e-15 56.3 0.0 1.5e-14 55.2 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG39276.1 - 2.2e-07 30.8 0.0 4.7e-07 29.7 0.0 1.6 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 OAG39276.1 - 0.00077 18.8 0.3 0.0013 18.1 0.3 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain PALP PF00291.25 OAG39276.1 - 0.0018 17.7 1.0 0.0035 16.8 1.0 1.5 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme TrkA_N PF02254.18 OAG39276.1 - 0.013 15.8 0.1 0.029 14.6 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain SIS_2 PF13580.6 OAG39276.1 - 0.065 13.2 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 SIS domain LDcluster4 PF18306.1 OAG39276.1 - 0.4 10.2 2.5 5.5 6.6 0.6 2.2 2 0 0 2 2 2 0 SLOG cluster4 family adh_short PF00106.25 OAG39277.1 - 1.5e-21 76.8 0.0 2.2e-21 76.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG39277.1 - 2.6e-15 56.6 0.1 4e-15 56.0 0.1 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG39277.1 - 6e-06 26.3 0.5 0.00012 22.0 0.5 2.2 1 1 0 1 1 1 1 KR domain Sugar_tr PF00083.24 OAG39278.1 - 3.7e-68 230.4 16.2 4.5e-68 230.2 16.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG39278.1 - 1.8e-26 92.9 18.3 1.8e-26 92.9 18.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Pyr_redox_3 PF13738.6 OAG39279.1 - 5.2e-10 39.1 0.2 2e-08 33.8 0.1 3.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 OAG39279.1 - 2.8e-09 36.0 0.0 2.4e-08 32.9 0.0 2.3 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 OAG39279.1 - 3e-09 36.5 0.0 4.3e-06 26.2 0.0 2.9 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG39279.1 - 2.3e-08 34.1 0.1 1.9e-07 31.2 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.20 OAG39279.1 - 4.2e-06 26.9 0.3 0.0048 17.0 0.0 2.8 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.6 OAG39279.1 - 8e-06 25.9 0.2 0.15 12.1 0.0 3.1 3 0 0 3 3 3 2 FAD-NAD(P)-binding DAO PF01266.24 OAG39279.1 - 1.1e-05 25.2 1.0 0.018 14.6 0.0 3.3 3 1 0 3 3 3 2 FAD dependent oxidoreductase ThiF PF00899.21 OAG39279.1 - 1.2e-05 24.9 0.0 0.012 14.9 0.0 2.3 2 0 0 2 2 2 2 ThiF family K_oxygenase PF13434.6 OAG39279.1 - 2.9e-05 23.4 0.0 0.015 14.5 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 OAG39279.1 - 0.0008 18.7 0.1 0.0042 16.4 0.1 2.0 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 OAG39279.1 - 0.0016 19.0 0.0 2.2 8.9 0.0 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAG39279.1 - 0.0027 16.9 0.0 0.0056 15.8 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 OAG39279.1 - 0.017 14.2 0.6 0.95 8.4 0.0 3.1 2 2 0 2 2 2 0 Lycopene cyclase protein TnpV PF14198.6 OAG39279.1 - 0.023 14.7 0.2 1.5 8.8 0.1 2.7 2 0 0 2 2 2 0 Transposon-encoded protein TnpV SmpA_OmlA PF04355.13 OAG39279.1 - 0.039 13.8 0.0 0.21 11.4 0.0 2.1 2 0 0 2 2 2 0 SmpA / OmlA family Thi4 PF01946.17 OAG39279.1 - 0.074 12.3 0.3 0.91 8.7 0.0 2.4 3 0 0 3 3 3 0 Thi4 family 2-Hacid_dh_C PF02826.19 OAG39279.1 - 0.08 12.3 0.0 0.25 10.7 0.0 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 OAG39279.1 - 0.085 13.0 0.0 0.39 10.9 0.0 2.1 2 0 0 2 2 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Fungal_trans PF04082.18 OAG39280.1 - 7.2e-11 41.6 0.0 1.5e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.25 OAG39281.1 - 1.6e-21 76.6 0.0 2.6e-12 46.6 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAG39281.1 - 6.4e-13 48.8 0.1 9.1e-06 25.4 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG39281.1 - 0.00015 21.8 0.2 0.0078 16.1 0.1 2.8 2 1 0 2 2 2 1 KR domain Sugar_tr PF00083.24 OAG39282.1 - 7.8e-83 278.8 26.5 9.2e-83 278.6 26.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG39282.1 - 1.9e-22 79.7 72.2 5.5e-19 68.3 41.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily FMO-like PF00743.19 OAG39283.1 - 1.1e-20 73.6 0.0 2.8e-19 68.9 0.0 2.1 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OAG39283.1 - 1.4e-10 41.2 0.0 4.1e-10 39.7 0.0 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 OAG39283.1 - 1.4e-08 34.3 0.0 1.9e-05 24.1 0.0 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG39283.1 - 4.1e-06 26.2 0.1 0.0064 15.7 0.0 3.2 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 OAG39283.1 - 6e-06 25.7 0.0 0.12 11.6 0.0 3.0 2 1 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAG39283.1 - 1e-05 25.6 0.2 0.048 13.7 0.0 3.3 3 0 0 3 3 3 2 FAD-NAD(P)-binding Thi4 PF01946.17 OAG39283.1 - 0.0063 15.8 0.2 0.61 9.3 0.0 2.9 3 0 0 3 3 3 1 Thi4 family Amino_oxidase PF01593.24 OAG39283.1 - 0.034 13.5 0.2 16 4.7 0.2 3.0 2 1 1 3 3 3 0 Flavin containing amine oxidoreductase DAO PF01266.24 OAG39283.1 - 0.034 13.7 0.3 0.82 9.2 0.1 2.6 2 1 1 3 3 3 0 FAD dependent oxidoreductase Cyclase PF04199.13 OAG39284.1 - 0.00014 22.1 0.0 0.035 14.3 0.0 2.3 1 1 1 2 2 2 2 Putative cyclase adh_short PF00106.25 OAG39285.1 - 1.4e-30 106.2 0.0 2.3e-30 105.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG39285.1 - 1e-20 74.4 0.0 1.6e-20 73.7 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG39285.1 - 6.9e-07 29.4 0.1 2.2e-06 27.7 0.0 1.7 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 OAG39285.1 - 0.096 12.1 0.0 1.5 8.2 0.0 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Methyltransf_25 PF13649.6 OAG39285.1 - 0.14 12.9 0.0 0.28 11.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain CMD PF02627.20 OAG39286.1 - 4.4e-07 29.9 0.0 0.0011 19.0 0.0 2.5 2 0 0 2 2 2 2 Carboxymuconolactone decarboxylase family Raf1_HTH PF18579.1 OAG39286.1 - 0.13 12.0 0.1 7.2 6.4 0.0 2.5 2 0 0 2 2 2 0 Rubisco accumulation factor 1 helix turn helix domain CMD PF02627.20 OAG39287.1 - 3.5e-19 68.6 0.1 4.8e-09 36.1 0.0 2.3 2 0 0 2 2 2 2 Carboxymuconolactone decarboxylase family Abhydrolase_1 PF00561.20 OAG39289.1 - 9.6e-24 84.4 0.0 1.4e-17 64.2 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG39289.1 - 6.4e-14 53.1 0.4 8.8e-14 52.6 0.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG39289.1 - 1.3e-09 37.6 0.0 1.5e-07 30.9 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 OAG39289.1 - 4.6e-05 23.5 0.0 8.4e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein TRI12 PF06609.13 OAG39290.1 - 2e-42 145.4 21.0 2.6e-42 145.1 21.0 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG39290.1 - 1e-14 54.3 53.5 1.3e-14 54.0 51.2 2.4 1 1 1 2 2 2 1 Major Facilitator Superfamily NAD_binding_2 PF03446.15 OAG39292.1 - 1e-31 110.2 0.0 1.5e-31 109.7 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 OAG39292.1 - 3.2e-22 79.0 0.0 6.2e-22 78.1 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 OAG39292.1 - 4.8e-05 23.9 0.9 9.3e-05 22.9 0.0 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent OCD_Mu_crystall PF02423.15 OAG39292.1 - 0.00047 19.2 0.0 0.00074 18.5 0.0 1.3 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family GFO_IDH_MocA PF01408.22 OAG39292.1 - 0.061 14.2 0.0 0.11 13.3 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold adh_short_C2 PF13561.6 OAG39293.1 - 4.4e-46 157.3 0.3 5.8e-46 156.9 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG39293.1 - 1e-45 155.6 0.3 1.4e-45 155.1 0.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG39293.1 - 8.8e-07 29.0 0.0 2.8e-06 27.4 0.0 1.7 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 OAG39293.1 - 0.00047 19.7 0.0 0.00069 19.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAG39293.1 - 0.053 12.9 0.0 0.077 12.4 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Urocanase PF01175.18 OAG39293.1 - 0.066 12.8 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Urocanase Rossmann-like domain adh_short_C2 PF13561.6 OAG39294.1 - 3.7e-57 193.6 1.8 4.5e-57 193.3 1.8 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG39294.1 - 1.2e-44 152.2 1.1 1.3e-44 152.0 1.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG39294.1 - 0.00047 20.1 0.4 0.00087 19.2 0.4 1.4 1 1 0 1 1 1 1 KR domain SWIRM-assoc_3 PF16498.5 OAG39294.1 - 0.0027 17.9 0.6 0.0061 16.8 0.6 1.6 1 0 0 1 1 1 1 SWIRM-associated domain at the C-terminal Abhydrolase_3 PF07859.13 OAG39295.1 - 6.9e-38 130.6 0.0 1.2e-37 129.9 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 OAG39295.1 - 1.8e-07 30.4 0.5 7.1e-07 28.5 0.5 1.7 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_2 PF02230.16 OAG39295.1 - 0.0003 20.7 0.0 0.00049 20.0 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Cutinase PF01083.22 OAG39295.1 - 0.003 17.5 0.0 0.0044 17.0 0.0 1.2 1 0 0 1 1 1 1 Cutinase Peptidase_S9 PF00326.21 OAG39295.1 - 0.0062 16.0 0.0 0.017 14.6 0.0 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 OAG39295.1 - 0.023 15.3 0.1 0.032 14.8 0.1 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family FAD_binding_3 PF01494.19 OAG39296.1 - 0.00032 20.0 0.0 0.00044 19.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain ZYG-11_interact PF05884.12 OAG39297.1 - 8.6 5.7 10.8 12 5.2 10.8 1.1 1 0 0 1 1 1 0 Interactor of ZYG-11 Fig1 PF12351.8 OAG39298.1 - 9.4e-09 35.5 2.1 9.4e-09 35.5 2.1 3.1 2 1 1 3 3 3 1 Ca2+ regulator and membrane fusion protein Fig1 Cluap1 PF10234.9 OAG39298.1 - 0.81 9.0 3.1 1.3 8.4 3.1 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 SUR7 PF06687.12 OAG39299.1 - 5.3e-23 81.8 13.7 6.6e-23 81.5 13.7 1.0 1 0 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.8 OAG39299.1 - 1.5 8.7 19.4 0.22 11.4 14.6 1.8 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 TcpE PF12648.7 OAG39299.1 - 4.7 7.8 7.0 3.5 8.2 4.0 2.2 2 0 0 2 2 2 0 TcpE family Big_7 PF17957.1 OAG39303.1 - 0.44 11.3 3.0 0.37 11.6 0.6 2.1 2 0 0 2 2 2 0 Bacterial Ig domain Aldedh PF00171.22 OAG39304.1 - 1.2e-153 512.0 0.1 1.3e-153 511.8 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 OAG39304.1 - 0.0036 16.8 0.0 0.012 15.1 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) Toluene_X PF03349.16 OAG39304.1 - 0.046 12.3 0.0 0.074 11.6 0.0 1.2 1 0 0 1 1 1 0 Outer membrane protein transport protein (OMPP1/FadL/TodX) FAD_binding_3 PF01494.19 OAG39305.1 - 9e-20 71.2 0.0 4.2e-11 42.7 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 OAG39305.1 - 2.4e-09 37.2 2.8 2e-05 24.4 0.0 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OAG39305.1 - 5.5e-08 32.3 2.4 8.4e-08 31.7 1.9 1.6 1 1 1 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 OAG39305.1 - 9e-07 28.4 1.0 0.0022 17.3 0.3 2.1 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG39305.1 - 7.2e-06 26.1 0.8 1.7e-05 24.9 0.3 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 OAG39305.1 - 1.2e-05 24.2 0.3 0.00028 19.7 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 OAG39305.1 - 0.0005 19.4 1.1 0.00086 18.6 1.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Kdo PF06293.14 OAG39305.1 - 0.008 15.6 0.0 0.024 14.0 0.0 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FAD_oxidored PF12831.7 OAG39305.1 - 0.0081 15.6 0.2 0.013 14.9 0.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 OAG39305.1 - 0.02 13.9 0.2 0.12 11.4 0.2 1.9 1 1 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.17 OAG39305.1 - 0.041 13.1 0.5 0.071 12.3 0.5 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.27 OAG39305.1 - 0.052 14.1 0.1 2.8 8.6 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OAG39305.1 - 0.13 11.3 0.8 0.41 9.7 0.9 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A FMN_dh PF01070.18 OAG39306.1 - 8e-101 337.5 0.0 9.4e-101 337.3 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 OAG39306.1 - 0.00048 19.4 0.3 0.00094 18.4 0.2 1.5 2 0 0 2 2 2 1 Conserved region in glutamate synthase IMPDH PF00478.25 OAG39306.1 - 0.00064 18.8 1.9 0.0018 17.4 0.7 2.0 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain Flag1_repress PF03614.13 OAG39306.1 - 0.019 14.7 0.0 0.21 11.4 0.1 2.1 2 0 0 2 2 2 0 Repressor of phase-1 flagellin His_biosynth PF00977.21 OAG39306.1 - 0.076 12.5 0.4 3.5 7.0 0.1 2.4 1 1 1 2 2 2 0 Histidine biosynthesis protein Pkinase PF00069.25 OAG39307.1 - 3.5e-63 213.5 0.0 4.2e-63 213.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG39307.1 - 8.2e-36 123.6 0.0 1.1e-35 123.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAG39307.1 - 9.2e-07 28.5 0.0 1.5e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OAG39307.1 - 0.00043 19.2 0.0 0.00062 18.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 OAG39307.1 - 0.12 11.9 0.0 3.4 7.2 0.0 2.1 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 KH_1 PF00013.29 OAG39308.1 - 5.8e-42 141.4 8.5 1.4e-16 60.1 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 OAG39308.1 - 4.5e-10 39.2 10.0 0.014 15.2 0.5 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 OAG39308.1 - 5.2e-09 35.8 5.5 0.014 15.3 0.4 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 OAG39308.1 - 0.00062 19.8 6.1 0.29 11.2 0.1 3.4 3 0 0 3 3 3 2 NusA-like KH domain MOEP19 PF16005.5 OAG39308.1 - 0.032 14.2 0.0 13 5.9 0.0 2.5 3 0 0 3 3 3 0 KH-like RNA-binding domain ADH_N PF08240.12 OAG39309.1 - 1.5e-29 102.1 0.9 2.2e-29 101.5 0.9 1.2 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG39309.1 - 7.3e-14 51.9 0.0 1.1e-13 51.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 OAG39309.1 - 0.0024 17.8 0.3 0.0024 17.8 0.3 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-associated Yippee-Mis18 PF03226.14 OAG39310.1 - 2.6e-19 69.3 0.7 3e-19 69.2 0.7 1.0 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.8 OAG39310.1 - 0.00043 20.5 1.5 0.00058 20.1 1.5 1.2 1 0 0 1 1 1 1 C-terminal domain of RIG-I CpXC PF14353.6 OAG39310.1 - 0.025 14.6 0.1 0.068 13.2 0.0 1.7 2 0 0 2 2 2 0 CpXC protein Eapp_C PF10238.9 OAG39310.1 - 0.075 13.1 2.1 1.2 9.2 0.3 2.1 1 1 1 2 2 2 0 E2F-associated phosphoprotein HECT_2 PF09814.9 OAG39310.1 - 0.16 10.8 0.7 0.61 8.9 0.0 1.8 1 1 1 2 2 2 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Evr1_Alr PF04777.13 OAG39310.1 - 0.21 12.1 1.3 5 7.6 0.1 2.1 1 1 1 2 2 2 0 Erv1 / Alr family RabGAP-TBC PF00566.18 OAG39312.1 - 6.6e-35 120.7 0.1 1e-34 120.1 0.1 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Pox_Ag35 PF03286.14 OAG39312.1 - 3.2 7.5 7.7 0.29 10.9 0.9 2.3 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Pkinase PF00069.25 OAG39313.1 - 2.1e-51 174.8 0.0 3.2e-50 171.0 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG39313.1 - 3e-17 62.8 0.0 5e-17 62.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OAG39313.1 - 7.1e-05 22.8 0.3 0.024 14.5 0.1 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 OAG39313.1 - 0.0025 17.2 0.0 0.0052 16.1 0.0 1.5 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 OAG39313.1 - 0.0029 17.2 0.0 0.0073 15.9 0.0 1.6 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 OAG39313.1 - 0.0045 16.0 0.0 0.0073 15.3 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 OAG39313.1 - 0.006 15.4 0.0 0.0089 14.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase LRR_6 PF13516.6 OAG39314.1 - 1.4e-13 49.7 0.4 0.0075 16.2 0.0 5.8 6 0 0 6 6 6 4 Leucine Rich repeat F-box-like PF12937.7 OAG39314.1 - 5.9e-10 38.9 0.1 1.5e-09 37.6 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAG39314.1 - 2.9e-06 27.0 0.1 1e-05 25.2 0.1 1.9 1 0 0 1 1 1 1 F-box domain LRR_4 PF12799.7 OAG39314.1 - 0.0063 16.9 0.1 0.0063 16.9 0.1 5.9 4 2 2 6 6 6 1 Leucine Rich repeats (2 copies) EF-hand_8 PF13833.6 OAG39314.1 - 0.15 12.0 1.2 2.4 8.1 0.0 3.2 4 0 0 4 4 4 0 EF-hand domain pair LRR_1 PF00560.33 OAG39314.1 - 4.1 8.3 15.6 12 6.9 0.0 6.2 7 0 0 7 7 7 0 Leucine Rich Repeat MBOAT PF03062.19 OAG39316.1 - 1.9e-31 109.7 21.2 1.1e-30 107.2 21.1 2.0 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Ring_hydroxyl_A PF00848.19 OAG39316.1 - 1.2e-23 84.2 2.1 8.1e-11 42.3 0.0 2.4 1 1 1 2 2 2 2 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.26 OAG39316.1 - 1.1e-12 47.7 0.0 2.1e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pex14_N PF04695.13 OAG39316.1 - 0.0028 18.3 0.0 0.012 16.3 0.0 1.9 2 0 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Flavodoxin_2 PF02525.17 OAG39317.1 - 3.7e-46 157.3 0.0 4.5e-46 157.1 0.0 1.0 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 OAG39317.1 - 5.3e-16 58.7 0.0 7.2e-16 58.3 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_4 PF12682.7 OAG39317.1 - 0.049 13.3 0.2 0.084 12.6 0.2 1.3 1 0 0 1 1 1 0 Flavodoxin Fungal_trans_2 PF11951.8 OAG39318.1 - 3.6e-17 62.2 1.7 6.9e-16 58.0 1.7 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Adaptin_N PF01602.20 OAG39319.1 - 9.8e-142 473.2 3.1 1.3e-141 472.8 3.1 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 OAG39319.1 - 7e-21 74.6 0.0 1.8e-20 73.3 0.0 1.8 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 OAG39319.1 - 8e-08 32.5 5.5 0.00043 20.4 0.0 4.3 2 2 2 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 OAG39319.1 - 1.3e-06 28.7 1.3 0.068 13.6 0.0 4.7 5 1 0 5 5 5 2 HEAT repeats DUF3730 PF12530.8 OAG39319.1 - 0.00019 21.1 0.0 0.0069 16.0 0.0 2.6 1 1 1 2 2 2 1 Protein of unknown function (DUF3730) HEAT PF02985.22 OAG39319.1 - 0.0045 17.1 1.8 6.4 7.3 0.1 4.4 4 0 0 4 4 4 1 HEAT repeat Arm PF00514.23 OAG39319.1 - 0.13 12.3 0.1 98 3.2 0.1 4.6 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat p450 PF00067.22 OAG39320.1 - 1.4e-66 225.1 0.0 1.8e-66 224.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 EamA PF00892.20 OAG39322.1 - 9.2e-12 45.3 23.7 2.8e-06 27.5 2.5 2.5 2 0 0 2 2 2 2 EamA-like transporter family Nuc_sug_transp PF04142.15 OAG39322.1 - 1.5e-08 34.2 0.3 1.5e-08 34.2 0.3 1.8 1 1 1 2 2 2 1 Nucleotide-sugar transporter TPT PF03151.16 OAG39322.1 - 3.3e-06 26.7 6.2 2.1e-05 24.0 0.2 2.5 2 0 0 2 2 2 2 Triose-phosphate Transporter family UAA PF08449.11 OAG39322.1 - 5.3e-05 22.6 9.5 5.3e-05 22.6 9.5 1.6 2 0 0 2 2 2 1 UAA transporter family DMT_6 PF04342.12 OAG39322.1 - 0.41 10.9 5.4 4 7.7 1.0 2.7 2 0 0 2 2 2 0 Putative member of DMT superfamily (DUF486) Fumble PF03630.14 OAG39323.1 - 6.1e-144 479.2 0.6 7.9e-144 478.9 0.6 1.1 1 0 0 1 1 1 1 Fumble adh_short_C2 PF13561.6 OAG39324.1 - 5.4e-27 94.9 0.1 7.5e-27 94.4 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG39324.1 - 4.5e-24 85.0 0.2 5.6e-24 84.7 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG39324.1 - 5.7e-05 23.1 0.2 8.9e-05 22.5 0.2 1.2 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 OAG39324.1 - 0.0022 17.4 0.0 0.0043 16.4 0.0 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ADH_zinc_N PF00107.26 OAG39324.1 - 0.015 15.3 0.2 0.034 14.1 0.2 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Sacchrp_dh_NADP PF03435.18 OAG39324.1 - 0.021 15.1 0.1 0.033 14.4 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_7 PF13241.6 OAG39324.1 - 0.023 15.1 0.0 0.051 14.0 0.1 1.6 2 0 0 2 2 2 0 Putative NAD(P)-binding Pyr_redox_2 PF07992.14 OAG39324.1 - 0.036 13.3 0.1 0.057 12.6 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 OAG39324.1 - 0.058 13.3 0.1 0.1 12.4 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.27 OAG39324.1 - 0.12 13.0 0.5 0.26 11.9 0.5 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase CMS1 PF14617.6 OAG39325.1 - 5.7e-54 183.1 0.1 6.9e-54 182.8 0.1 1.1 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.29 OAG39325.1 - 0.001 18.9 0.0 0.0019 18.0 0.0 1.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase dCMP_cyt_deam_1 PF00383.23 OAG39326.1 - 2.8e-09 36.7 0.1 4.5e-09 36.1 0.1 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 OAG39326.1 - 8.9e-08 32.0 0.0 1.3e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 MafB19-like deaminase SNAD4 PF18750.1 OAG39326.1 - 0.031 14.4 0.3 0.057 13.6 0.3 1.3 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 LcrG PF07216.12 OAG39326.1 - 0.21 11.5 0.0 0.37 10.7 0.0 1.4 1 0 0 1 1 1 0 LcrG protein DEAD PF00270.29 OAG39327.1 - 5.2e-42 143.6 0.0 1.1e-41 142.6 0.0 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAG39327.1 - 5.5e-30 104.0 0.0 1.4e-29 102.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG39327.1 - 5.5e-06 26.5 0.0 3.2e-05 24.0 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 OAG39327.1 - 0.034 12.9 0.0 0.048 12.4 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain AAA_22 PF13401.6 OAG39327.1 - 0.075 13.3 0.0 0.5 10.6 0.0 2.4 2 1 0 2 2 2 0 AAA domain ERCC3_RAD25_C PF16203.5 OAG39327.1 - 0.089 12.0 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Glyco_transf_28 PF03033.20 OAG39328.1 - 1.3e-22 80.3 0.0 3.2e-22 79.1 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 OAG39328.1 - 1.9e-05 23.7 0.0 3e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 OAG39328.1 - 0.0057 16.7 0.0 0.018 15.0 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase family 28 C-terminal domain ATG_C PF09333.11 OAG39328.1 - 0.019 15.3 2.9 0.11 12.8 0.1 3.2 3 1 0 3 3 3 0 Autophagy-related protein C terminal domain VPS13_C PF16909.5 OAG39328.1 - 0.24 11.1 4.5 0.12 12.2 0.2 2.3 2 0 0 2 2 2 0 Vacuolar-sorting-associated 13 protein C-terminal GFA PF04828.14 OAG39329.1 - 0.00023 21.4 0.1 0.00023 21.4 0.1 1.7 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme SOR_SNZ PF01680.17 OAG39330.1 - 2.8e-107 357.1 7.4 4e-107 356.7 7.4 1.2 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.14 OAG39330.1 - 4.8e-07 29.3 9.9 8e-06 25.3 2.3 2.5 2 1 0 2 2 2 2 Thiazole biosynthesis protein ThiG Dus PF01207.17 OAG39330.1 - 5.2e-05 22.5 0.5 0.1 11.7 0.1 2.6 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 OAG39330.1 - 0.00026 20.5 0.7 0.15 11.5 0.0 2.8 2 1 1 3 3 3 2 Histidine biosynthesis protein NanE PF04131.14 OAG39330.1 - 0.0029 16.8 1.1 0.049 12.8 0.0 2.8 2 2 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase Ribosomal_L29 PF00831.23 OAG39330.1 - 0.011 15.7 0.2 0.072 13.1 0.1 2.1 2 0 0 2 2 2 0 Ribosomal L29 protein IGPS PF00218.21 OAG39330.1 - 0.014 14.6 0.2 0.4 9.8 0.0 2.4 2 1 0 2 2 2 0 Indole-3-glycerol phosphate synthase TetR_C_27 PF17935.1 OAG39330.1 - 0.014 15.4 0.0 0.036 14.1 0.0 1.6 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain NMO PF03060.15 OAG39330.1 - 0.095 12.1 10.7 0.097 12.0 3.3 2.2 2 0 0 2 2 2 0 Nitronate monooxygenase Fungal_trans PF04082.18 OAG39331.1 - 3e-13 49.4 0.1 1e-12 47.7 0.1 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain AA_permease PF00324.21 OAG39332.1 - 3.1e-123 411.9 38.3 3.7e-123 411.7 38.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAG39332.1 - 4e-35 121.5 40.1 5e-35 121.1 40.1 1.1 1 0 0 1 1 1 1 Amino acid permease Aminotran_3 PF00202.21 OAG39333.1 - 9.9e-85 284.6 0.0 1.3e-84 284.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III NUMOD1 PF07453.13 OAG39333.1 - 0.14 12.5 0.0 0.51 10.7 0.0 2.0 2 0 0 2 2 2 0 NUMOD1 domain DUF3425 PF11905.8 OAG39334.1 - 3.8e-10 39.8 1.3 6.4e-10 39.1 0.1 2.0 2 1 0 2 2 2 1 Domain of unknown function (DUF3425) CCDC-167 PF15188.6 OAG39334.1 - 0.89 9.9 4.4 5.9 7.3 4.4 2.1 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 Glyoxalase PF00903.25 OAG39335.1 - 2.9e-13 50.1 0.0 3.9e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 OAG39335.1 - 1.5e-11 45.0 0.0 3.9e-11 43.7 0.0 1.6 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.6 OAG39335.1 - 3.1e-10 40.3 0.0 4.4e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 OAG39335.1 - 0.00031 20.9 0.2 0.0079 16.3 0.1 2.1 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_2 PF12681.7 OAG39335.1 - 0.0079 16.1 0.0 0.71 9.8 0.0 2.1 2 0 0 2 2 2 2 Glyoxalase-like domain Fungal_trans PF04082.18 OAG39336.1 - 2.8e-11 43.0 1.7 3.2e-11 42.8 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG39336.1 - 4.2e-07 30.0 8.0 9.1e-07 28.9 8.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sporozoite_P67 PF05642.11 OAG39336.1 - 0.085 10.9 8.9 0.16 10.0 8.9 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SSP160 PF06933.11 OAG39336.1 - 1.6 6.8 15.8 2.4 6.2 15.8 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 NmrA PF05368.13 OAG39337.1 - 1.1e-07 31.7 0.0 3e-07 30.2 0.0 1.7 1 1 0 1 1 1 1 NmrA-like family AMP-binding PF00501.28 OAG39338.1 - 2.1e-90 303.3 0.0 2.8e-90 303.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG39338.1 - 1.1e-11 45.5 0.2 2.3e-11 44.5 0.2 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Rho_RNA_bind PF07497.12 OAG39338.1 - 0.11 12.4 0.0 0.4 10.6 0.0 1.9 1 0 0 1 1 1 0 Rho termination factor, RNA-binding domain NAD_binding_8 PF13450.6 OAG39339.1 - 5.5e-14 52.2 0.0 1.3e-13 50.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.19 OAG39339.1 - 4.7e-13 48.4 0.1 7.8e-10 37.8 0.1 2.7 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 OAG39339.1 - 1.9e-07 30.6 0.0 0.00047 19.5 0.0 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAG39339.1 - 7.3e-05 22.5 0.0 0.041 13.5 0.0 2.7 2 1 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 OAG39339.1 - 0.0024 17.9 0.0 0.021 14.8 0.0 2.4 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 OAG39339.1 - 0.0054 16.0 0.0 0.13 11.5 0.0 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG39339.1 - 0.015 14.5 0.0 1 8.5 0.0 2.6 3 0 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 OAG39339.1 - 0.15 10.7 0.0 0.24 10.1 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.22 OAG39339.1 - 0.17 10.9 0.0 3.1 6.8 0.0 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A Thi4 PF01946.17 OAG39339.1 - 0.19 10.9 0.0 0.43 9.8 0.0 1.5 1 0 0 1 1 1 0 Thi4 family TRI12 PF06609.13 OAG39340.1 - 1.1e-79 268.5 21.5 1.3e-79 268.3 21.5 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG39340.1 - 1.7e-24 86.4 49.9 1.7e-24 86.4 49.9 3.1 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG39340.1 - 8.7e-18 64.4 2.2 8.7e-18 64.4 2.2 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter Aldolase_II PF00596.21 OAG39341.1 - 8.9e-49 165.9 0.0 1.1e-48 165.6 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain ScdA_N PF04405.14 OAG39341.1 - 0.12 12.0 0.1 0.27 10.9 0.1 1.6 1 0 0 1 1 1 0 Domain of Unknown function (DUF542) adh_short PF00106.25 OAG39342.1 - 1.2e-30 106.5 0.0 1.7e-30 106.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG39342.1 - 8.1e-22 77.9 0.0 1.3e-21 77.2 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase TrkA_N PF02254.18 OAG39342.1 - 0.012 15.8 0.0 0.026 14.8 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain DUF3924 PF13062.6 OAG39342.1 - 0.033 14.1 0.1 0.2 11.6 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3924) NAD_binding_2 PF03446.15 OAG39342.1 - 0.084 13.0 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase ADH_N PF08240.12 OAG39343.1 - 2e-22 79.2 3.7 6e-22 77.6 3.4 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG39343.1 - 6.9e-21 74.6 0.0 1.3e-20 73.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 OAG39343.1 - 1.3e-10 41.2 0.0 1.9e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 OAG39343.1 - 2.4e-05 25.4 0.0 4.3e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Sacchrp_dh_NADP PF03435.18 OAG39343.1 - 0.0032 17.7 0.1 0.0082 16.4 0.1 1.6 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain ADH_N_assoc PF13823.6 OAG39343.1 - 0.14 12.1 0.2 0.46 10.5 0.2 1.9 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-associated FAD_binding_3 PF01494.19 OAG39343.1 - 0.19 10.9 0.2 0.28 10.4 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain 2-Hacid_dh_C PF02826.19 OAG39343.1 - 0.21 10.9 0.0 0.35 10.2 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox PF00070.27 OAG39343.1 - 0.39 11.3 2.0 1.2 9.7 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 OAG39343.1 - 0.75 9.0 4.4 0.16 11.3 1.2 1.5 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain AMP-binding PF00501.28 OAG39344.1 - 1.7e-53 181.7 0.0 2.3e-53 181.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG39344.1 - 0.00063 20.7 0.0 0.0017 19.3 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 OAG39344.1 - 0.00097 19.0 0.0 0.0054 16.6 0.0 2.3 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus Thiolase_N PF00108.23 OAG39345.1 - 3.7e-60 203.5 0.0 4.5e-60 203.2 0.0 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 OAG39345.1 - 1.3e-39 134.7 0.0 2.5e-39 133.7 0.0 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III PF08545.10 OAG39345.1 - 0.0037 17.1 0.0 0.23 11.3 0.0 2.4 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.26 OAG39345.1 - 0.0052 16.4 0.1 0.016 14.8 0.1 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ADH_N PF08240.12 OAG39346.1 - 4.8e-21 74.7 1.0 2.7e-20 72.3 0.4 2.3 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG39346.1 - 1.2e-15 57.6 0.2 2.4e-15 56.6 0.1 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ELFV_dehydrog PF00208.21 OAG39346.1 - 0.027 14.2 0.1 0.04 13.6 0.1 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase FAD_binding_3 PF01494.19 OAG39347.1 - 7.9e-16 58.2 0.0 1.5e-15 57.4 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAG39347.1 - 2.8e-11 43.6 1.4 0.0001 22.1 1.5 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG39347.1 - 1.8e-09 37.3 0.2 1.1e-05 24.8 0.2 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG39347.1 - 2.1e-09 37.4 0.1 4.5e-09 36.4 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 OAG39347.1 - 1e-07 31.4 0.6 2.2e-07 30.3 0.6 1.6 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.24 OAG39347.1 - 1.5e-06 27.8 0.2 0.013 14.8 0.1 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase HI0933_like PF03486.14 OAG39347.1 - 1.7e-06 27.0 0.4 7.9e-05 21.5 0.3 2.2 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 OAG39347.1 - 6.5e-06 26.6 0.0 6e-05 23.5 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 OAG39347.1 - 1e-05 25.1 0.0 1.5e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 OAG39347.1 - 3.7e-05 22.9 0.3 0.12 11.3 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein Trp_halogenase PF04820.14 OAG39347.1 - 6.6e-05 21.9 3.3 0.099 11.5 0.0 2.3 1 1 0 2 2 2 2 Tryptophan halogenase GIDA PF01134.22 OAG39347.1 - 0.00013 21.2 0.3 0.00042 19.5 0.3 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.17 OAG39347.1 - 0.00017 21.0 0.0 0.00032 20.0 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 OAG39347.1 - 0.0072 15.6 0.2 0.032 13.5 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAG39347.1 - 0.011 15.7 0.4 0.1 12.6 0.4 2.3 1 1 0 1 1 1 0 FAD-NAD(P)-binding DUF1188 PF06690.11 OAG39347.1 - 0.021 14.4 0.0 0.035 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) AlaDh_PNT_C PF01262.21 OAG39347.1 - 0.069 12.4 0.2 0.14 11.4 0.2 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain MCRA PF06100.11 OAG39347.1 - 0.14 11.0 0.1 0.23 10.2 0.1 1.2 1 0 0 1 1 1 0 MCRA family Cupin_2 PF07883.11 OAG39348.1 - 6.6e-26 89.8 0.5 3.6e-16 58.6 0.1 2.3 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.19 OAG39348.1 - 2.1e-07 30.9 0.2 0.0094 15.9 0.1 2.2 2 0 0 2 2 2 2 AraC-like ligand binding domain Cupin_3 PF05899.12 OAG39348.1 - 1.4e-05 24.7 0.1 0.14 11.9 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) CENP-C_C PF11699.8 OAG39348.1 - 0.00017 21.7 0.0 0.0011 19.1 0.0 2.0 2 0 0 2 2 2 1 Mif2/CENP-C like ARD PF03079.14 OAG39348.1 - 0.0027 17.9 0.1 0.21 11.8 0.0 2.5 3 0 0 3 3 3 1 ARD/ARD' family SPT2 PF08243.11 OAG39349.1 - 1.1e-08 35.5 11.2 1.1e-08 35.5 11.2 2.1 2 0 0 2 2 2 1 SPT2 chromatin protein Ribosomal_60s PF00428.19 OAG39350.1 - 3.4e-26 91.7 10.3 4e-26 91.4 10.3 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein RibD_C PF01872.17 OAG39350.1 - 0.14 12.0 0.0 0.19 11.5 0.0 1.2 1 0 0 1 1 1 0 RibD C-terminal domain Cytomega_UL84 PF06284.11 OAG39350.1 - 0.17 10.3 1.3 0.18 10.2 1.3 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein Ribosomal_S19 PF00203.21 OAG39351.1 - 4.4e-34 116.2 0.2 6.1e-34 115.8 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 DUF4187 PF13821.6 OAG39353.1 - 2.4e-22 78.5 5.6 8.8e-22 76.6 5.6 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.23 OAG39353.1 - 6.9e-08 32.3 0.4 2.2e-07 30.7 0.4 1.9 1 1 0 1 1 1 1 G-patch domain DUF3533 PF12051.8 OAG39354.1 - 1.4e-113 379.7 6.6 1.7e-113 379.4 6.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) Neurensin PF14927.6 OAG39354.1 - 0.19 11.5 1.6 2 8.1 0.3 2.9 3 0 0 3 3 3 0 Neurensin VIT1 PF01988.19 OAG39354.1 - 0.56 10.0 2.4 25 4.6 2.1 2.6 2 1 0 2 2 2 0 VIT family Nop14 PF04147.12 OAG39355.1 - 4.9e-271 901.9 27.0 5.8e-271 901.6 27.0 1.0 1 0 0 1 1 1 1 Nop14-like family Noc2 PF03715.13 OAG39355.1 - 0.019 14.2 0.0 0.059 12.6 0.0 1.8 1 0 0 1 1 1 0 Noc2p family adh_short PF00106.25 OAG39356.1 - 3.5e-36 124.5 0.2 5.2e-36 123.9 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG39356.1 - 1.9e-23 83.2 0.1 2.6e-23 82.8 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 OAG39356.1 - 2.3e-06 27.2 0.0 4.7e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) KR PF08659.10 OAG39356.1 - 2.5e-06 27.6 0.2 4.3e-06 26.8 0.2 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 OAG39356.1 - 0.0003 20.7 0.1 0.00044 20.2 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAG39356.1 - 0.027 13.9 0.0 0.048 13.1 0.0 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NmrA PF05368.13 OAG39356.1 - 0.028 14.0 0.3 0.048 13.2 0.3 1.3 1 0 0 1 1 1 0 NmrA-like family ADH_zinc_N PF00107.26 OAG39356.1 - 0.044 13.8 0.1 0.091 12.7 0.1 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Eno-Rase_NADH_b PF12242.8 OAG39356.1 - 0.049 13.4 0.1 0.21 11.4 0.1 2.0 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Sec66 PF09802.9 OAG39357.1 - 2.7e-69 232.4 0.0 3.3e-69 232.1 0.0 1.1 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 Nnf1 PF03980.14 OAG39357.1 - 0.019 15.4 0.1 4.6 7.7 0.0 3.1 3 0 0 3 3 3 0 Nnf1 DUF4407 PF14362.6 OAG39357.1 - 0.049 13.0 0.0 0.069 12.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Med3 PF11593.8 OAG39357.1 - 0.65 9.1 10.6 0.82 8.8 10.6 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal CCDC53 PF10152.9 OAG39357.1 - 1.3 9.4 4.5 2.7 8.4 4.5 1.5 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex TPR_MLP1_2 PF07926.12 OAG39357.1 - 1.7 8.7 8.0 0.31 11.1 3.3 1.9 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein CENP-U PF13097.6 OAG39357.1 - 5.4 6.9 8.6 0.17 11.8 2.6 1.6 2 0 0 2 2 2 0 CENP-A nucleosome associated complex (NAC) subunit PPR_2 PF13041.6 OAG39358.1 - 1e-06 28.8 0.0 0.21 11.8 0.0 5.3 5 1 1 6 6 6 2 PPR repeat family PPR PF01535.20 OAG39358.1 - 0.0014 18.7 0.0 39 4.8 0.0 5.4 5 0 0 5 5 5 1 PPR repeat Profilin PF00235.19 OAG39358.1 - 0.1 12.9 0.2 6.9 7.0 0.0 3.0 3 0 0 3 3 3 0 Profilin TPR_4 PF07721.14 OAG39358.1 - 2.5 9.0 7.9 31 5.6 0.4 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat ORC_WH_C PF18137.1 OAG39359.1 - 1.1e-27 96.8 0.0 2.9e-27 95.5 0.0 1.8 1 0 0 1 1 1 1 Origin recognition complex winged helix C-terminal ORC3_N PF07034.11 OAG39359.1 - 3.7e-19 69.0 3.8 1e-12 47.8 0.5 2.4 1 1 1 2 2 2 2 Origin recognition complex (ORC) subunit 3 N-terminus RsbRD_N PF14361.6 OAG39359.1 - 0.019 15.6 1.6 0.91 10.2 0.1 3.7 4 0 0 4 4 4 0 RsbT co-antagonist protein rsbRD N-terminal domain CENP-B_dimeris PF09026.10 OAG39359.1 - 0.16 12.4 3.4 0.93 9.9 4.2 1.9 2 0 0 2 2 2 0 Centromere protein B dimerisation domain zf-C2H2 PF00096.26 OAG39360.1 - 9.1e-05 22.7 8.5 0.0012 19.2 2.1 8.3 8 1 0 8 8 8 4 Zinc finger, C2H2 type zf-C2H2_aberr PF17017.5 OAG39360.1 - 0.00017 21.8 1.7 0.00017 21.8 1.7 2.8 2 1 0 2 2 2 1 Aberrant zinc-finger zf-H2C2_5 PF13909.6 OAG39360.1 - 0.0014 18.4 1.2 0.0014 18.4 1.2 5.9 5 0 0 5 5 5 2 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 OAG39360.1 - 0.0055 17.4 54.4 0.14 13.1 0.2 8.8 8 0 0 8 8 8 4 C2H2-type zinc finger zf-C2H2 PF00096.26 OAG39361.1 - 2 9.1 28.5 0.97 10.0 0.7 4.7 4 0 0 4 4 4 0 Zinc finger, C2H2 type FOXP-CC PF16159.5 OAG39361.1 - 2.5 8.8 13.6 0.88 10.2 1.0 3.6 2 1 1 3 3 3 0 FOXP coiled-coil domain FAM176 PF14851.6 OAG39361.1 - 2.9 7.5 9.1 0.77 9.4 4.1 2.5 2 0 0 2 2 2 0 FAM176 family DUF3999 PF13163.6 OAG39363.1 - 0.063 12.5 0.0 0.092 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3999) Carb_kinase PF01256.17 OAG39364.1 - 1.2e-51 175.6 0.0 1.5e-51 175.2 0.0 1.1 1 0 0 1 1 1 1 Carbohydrate kinase Epimerase PF01370.21 OAG39365.1 - 1.2e-16 60.9 0.1 1.9e-16 60.3 0.1 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OAG39365.1 - 4.5e-11 42.3 0.0 5.9e-11 41.9 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 OAG39365.1 - 4.5e-10 39.7 0.1 1.2e-09 38.3 0.1 1.8 1 1 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 OAG39365.1 - 3.9e-08 32.8 0.1 9.8e-08 31.5 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.25 OAG39365.1 - 6.5e-07 29.0 0.2 0.0003 20.3 0.0 2.7 2 1 0 2 2 2 2 short chain dehydrogenase GDP_Man_Dehyd PF16363.5 OAG39365.1 - 0.00035 20.1 0.0 0.00063 19.2 0.0 1.3 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 OAG39365.1 - 0.001 18.3 0.0 0.01 15.0 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.13 OAG39365.1 - 0.0014 18.2 0.0 0.0022 17.6 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family DUF3807 PF12720.7 OAG39366.1 - 5.8e-28 98.4 3.3 7.5e-28 98.0 3.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3807) E1-E2_ATPase PF00122.20 OAG39367.1 - 2.5e-37 128.1 2.1 1e-35 122.9 0.1 3.4 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 OAG39367.1 - 5.1e-16 59.6 0.0 1.4e-15 58.2 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 OAG39367.1 - 2.1e-11 43.3 0.0 4.4e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 OAG39367.1 - 0.0031 17.3 0.1 0.0058 16.4 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 OAG39367.1 - 0.0035 17.4 0.0 0.0074 16.3 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Nrf1_activ_bdg PF10492.9 OAG39368.1 - 0.12 13.1 2.7 0.32 11.7 2.7 1.8 1 0 0 1 1 1 0 Nrf1 activator activation site binding domain Abhydrolase_3 PF07859.13 OAG39369.1 - 2.1e-39 135.6 0.0 2.2e-37 129.0 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 OAG39369.1 - 6.1e-08 32.0 0.1 3.1e-07 29.6 0.1 1.8 1 1 0 1 1 1 1 Carboxylesterase family tRNA-synt_2 PF00152.20 OAG39370.1 - 2.1e-71 240.6 0.0 3.3e-71 240.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.9 OAG39370.1 - 5e-17 61.9 0.0 7.2e-17 61.3 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2156) tRNA_anti-codon PF01336.25 OAG39370.1 - 0.0069 16.3 0.1 0.015 15.3 0.1 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain MCM_N PF14551.6 OAG39370.1 - 0.014 16.0 0.1 0.05 14.2 0.1 2.0 1 0 0 1 1 1 0 MCM N-terminal domain tRNA-synt_2d PF01409.20 OAG39370.1 - 0.022 14.2 0.4 4.5 6.7 0.0 2.4 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) WLM PF08325.10 OAG39371.1 - 1.1e-61 208.3 0.2 2.2e-61 207.3 0.1 1.6 2 0 0 2 2 2 1 WLM domain zf-RanBP PF00641.18 OAG39371.1 - 0.00049 19.4 0.4 0.00049 19.4 0.4 3.0 3 0 0 3 3 3 2 Zn-finger in Ran binding protein and others DUF45 PF01863.17 OAG39371.1 - 0.024 14.7 2.5 0.024 14.7 2.5 2.1 2 0 0 2 2 2 0 Protein of unknown function DUF45 DZR PF12773.7 OAG39371.1 - 0.77 9.8 7.0 9.8 6.3 6.2 2.5 2 1 1 3 3 3 0 Double zinc ribbon C1_2 PF03107.16 OAG39371.1 - 1 9.7 4.0 13 6.2 0.1 2.9 2 1 1 3 3 3 0 C1 domain zf-Sec23_Sec24 PF04810.15 OAG39371.1 - 3.9 7.6 10.6 0.76 9.9 0.1 3.1 2 1 0 2 2 2 0 Sec23/Sec24 zinc finger DUF1776 PF08643.10 OAG39372.1 - 2.3e-44 151.9 0.0 4.1e-23 82.2 0.0 2.1 1 1 1 2 2 2 2 Fungal family of unknown function (DUF1776) Clr5 PF14420.6 OAG39373.1 - 6e-19 68.0 0.5 1.6e-18 66.6 0.5 1.8 1 0 0 1 1 1 1 Clr5 domain zf-C2H2 PF00096.26 OAG39375.1 - 1e-09 38.3 11.6 2.2e-05 24.7 4.5 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OAG39375.1 - 2.5e-09 37.2 14.1 3.7e-05 23.9 0.4 3.6 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 OAG39375.1 - 9.4e-07 29.2 10.9 0.0013 19.4 3.2 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 OAG39375.1 - 5.5e-06 26.6 1.3 1.8e-05 25.0 1.3 1.9 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 OAG39375.1 - 0.00011 22.1 9.4 0.00012 22.0 2.4 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OAG39375.1 - 0.00074 19.7 1.8 0.00074 19.7 1.8 2.8 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 OAG39375.1 - 0.063 13.6 1.2 0.063 13.6 1.2 2.2 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.6 OAG39375.1 - 0.11 12.5 4.2 2.9 7.9 0.4 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Actin_micro PF17003.5 OAG39375.1 - 0.17 11.0 0.4 0.25 10.5 0.4 1.2 1 0 0 1 1 1 0 Putative actin-like family zf-C2H2_11 PF16622.5 OAG39375.1 - 0.36 10.6 7.2 6.6 6.6 0.8 2.8 2 0 0 2 2 2 0 zinc-finger C2H2-type Sec1 PF00995.23 OAG39377.1 - 1.7e-115 387.4 0.0 2.2e-115 387.1 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Exo_endo_phos PF03372.23 OAG39378.1 - 3.3e-07 30.1 0.0 6.6e-07 29.1 0.0 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Mito_carr PF00153.27 OAG39380.1 - 9.9e-59 195.3 1.0 2.3e-22 78.7 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Cgr1 PF03879.14 OAG39381.1 - 5.9e-31 107.0 30.7 6.5e-31 106.9 30.7 1.0 1 0 0 1 1 1 1 Cgr1 family Caldesmon PF02029.15 OAG39381.1 - 0.027 13.2 18.9 0.029 13.1 18.9 1.0 1 0 0 1 1 1 0 Caldesmon DUF262 PF03235.14 OAG39381.1 - 0.27 11.4 7.3 0.28 11.3 7.3 1.0 1 0 0 1 1 1 0 Protein of unknown function DUF262 DUF4192 PF13830.6 OAG39381.1 - 2.2 8.3 8.0 2.7 8.0 8.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) COX16 PF14138.6 OAG39381.1 - 6.9 7.3 12.3 10 6.7 12.3 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 Pal1 PF08316.11 OAG39382.1 - 3.2e-07 31.2 1.1 1.4e-06 29.1 0.2 2.5 2 1 0 2 2 2 1 Pal1 cell morphology protein 4HBT_2 PF13279.6 OAG39383.1 - 2.5e-26 92.6 0.0 3.7e-26 92.0 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 OAG39383.1 - 0.17 12.2 0.0 0.31 11.4 0.0 1.4 1 0 0 1 1 1 0 Thioesterase superfamily adh_short_C2 PF13561.6 OAG39385.1 - 1.3e-53 182.0 0.7 1.6e-53 181.6 0.7 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG39385.1 - 3e-39 134.5 0.2 4.7e-39 133.9 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG39385.1 - 4.1e-07 30.1 1.3 1.9e-06 27.9 1.2 2.1 1 1 0 1 1 1 1 KR domain Pkinase PF00069.25 OAG39386.1 - 4.3e-68 229.5 0.0 5.7e-68 229.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG39386.1 - 9.4e-36 123.4 0.0 1.5e-35 122.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAG39386.1 - 1.2e-05 24.8 0.0 1.6e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OAG39386.1 - 0.0018 17.7 0.0 0.0034 16.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OAG39386.1 - 0.0033 16.3 0.0 0.0061 15.4 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 OAG39386.1 - 0.0039 16.8 1.4 2.2 7.8 0.0 2.9 3 0 0 3 3 3 2 Kinetochore Sim4 complex subunit FTA2 YrbL-PhoP_reg PF10707.9 OAG39386.1 - 0.022 14.3 0.0 0.082 12.4 0.0 2.1 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Haem_degrading PF03928.14 OAG39387.1 - 7.5e-30 103.4 0.2 8.7e-30 103.2 0.2 1.0 1 0 0 1 1 1 1 Haem-degrading adh_short PF00106.25 OAG39388.1 - 9.1e-34 116.6 0.0 1.2e-33 116.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG39388.1 - 2.5e-25 89.4 0.0 3.3e-25 89.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG39388.1 - 5.5e-05 23.2 0.0 9e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 OAG39388.1 - 0.00015 22.0 0.1 0.00025 21.3 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 OAG39388.1 - 0.0006 19.3 0.0 0.00092 18.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 OAG39388.1 - 0.011 15.6 0.2 0.017 15.0 0.2 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 OAG39388.1 - 0.037 14.1 0.0 0.058 13.5 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 OAG39388.1 - 0.049 13.9 0.0 0.078 13.2 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain NmrA PF05368.13 OAG39388.1 - 0.055 13.0 0.4 0.088 12.3 0.4 1.3 1 0 0 1 1 1 0 NmrA-like family Amino_oxidase PF01593.24 OAG39390.1 - 2.7e-58 198.3 0.0 7.5e-58 196.9 0.0 1.6 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OAG39390.1 - 6.6e-13 48.7 0.3 1.3e-12 47.7 0.3 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAG39390.1 - 3.7e-07 29.7 0.0 2.2e-06 27.1 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAG39390.1 - 8.6e-07 28.9 0.5 1.4e-06 28.2 0.5 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 OAG39390.1 - 2e-06 27.3 0.6 3.1e-06 26.7 0.6 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 OAG39390.1 - 2.6e-06 26.8 0.9 1.2e-05 24.6 0.9 2.0 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 OAG39390.1 - 9e-06 25.1 0.8 1.7e-05 24.2 0.8 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 OAG39390.1 - 0.00018 22.0 0.4 0.0019 18.7 0.8 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAG39390.1 - 0.00033 20.0 0.1 0.00084 18.6 0.1 1.6 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 OAG39390.1 - 0.00045 19.0 0.2 0.00074 18.3 0.2 1.3 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.22 OAG39390.1 - 0.00064 18.9 0.3 0.00064 18.9 0.3 1.6 2 0 0 2 2 2 1 Glucose inhibited division protein A K_oxygenase PF13434.6 OAG39390.1 - 0.0056 15.9 0.1 0.13 11.4 0.0 2.5 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.12 OAG39390.1 - 0.0084 15.2 0.2 0.012 14.7 0.2 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_oxidored PF12831.7 OAG39390.1 - 0.0091 15.4 0.1 0.012 15.0 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 OAG39390.1 - 0.027 13.7 0.2 0.045 13.0 0.2 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 OAG39390.1 - 0.036 14.0 0.2 0.06 13.2 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 OAG39390.1 - 0.21 11.9 0.4 0.46 10.7 0.4 1.6 1 0 0 1 1 1 0 TrkA-N domain MFS_1 PF07690.16 OAG39391.1 - 2.6e-27 95.7 19.9 2.6e-27 95.7 19.9 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Coiled-coil_56 PF09813.9 OAG39391.1 - 0.0026 17.8 0.0 0.0056 16.7 0.0 1.5 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 Gly-zipper_Omp PF13488.6 OAG39391.1 - 0.14 12.2 1.5 0.45 10.5 0.2 2.5 2 0 0 2 2 2 0 Glycine zipper Sds3 PF08598.11 OAG39392.1 - 4.8e-18 66.0 4.1 4.8e-18 66.0 4.1 2.9 2 2 0 2 2 2 1 Sds3-like RRM_1 PF00076.22 OAG39393.1 - 8.7e-14 51.1 0.1 2.3e-11 43.3 0.0 2.9 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNase_T PF00929.24 OAG39394.1 - 1.9e-07 31.8 0.0 2.4e-06 28.2 0.0 2.5 1 1 0 1 1 1 1 Exonuclease STT3 PF02516.14 OAG39395.1 - 3.6e-143 478.0 35.6 3.3e-138 461.7 33.3 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit Arylsulfotran_2 PF14269.6 OAG39396.1 - 2.6e-59 201.1 5.7 3.7e-59 200.6 5.7 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 OAG39396.1 - 1.3e-18 67.1 1.5 3.4e-18 65.7 1.5 1.5 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) PGA2 PF07543.12 OAG39397.1 - 1.5e-17 63.9 0.5 2.4e-17 63.2 0.5 1.3 1 0 0 1 1 1 1 Protein trafficking PGA2 Crl PF07417.12 OAG39397.1 - 0.00052 20.1 0.1 0.0011 19.1 0.0 1.5 2 0 0 2 2 2 1 Sigma factor-binding transcriptional regulator Crl Tyrosinase PF00264.20 OAG39398.1 - 8.1e-47 160.4 3.2 1.5e-46 159.5 3.2 1.4 1 0 0 1 1 1 1 Common central domain of tyrosinase Tyosinase_C PF18132.1 OAG39398.1 - 2.6e-26 92.7 0.0 4.5e-26 91.9 0.0 1.4 1 0 0 1 1 1 1 Tyosinase C-terminal domain GPI-anchored PF10342.9 OAG39399.1 - 8.2e-15 55.3 0.3 8.2e-15 55.3 0.3 2.2 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family SHE3 PF17078.5 OAG39400.1 - 2.4e-07 30.7 24.1 8.9e-06 25.6 24.1 2.1 1 1 0 1 1 1 1 SWI5-dependent HO expression protein 3 ADIP PF11559.8 OAG39400.1 - 0.00023 21.3 32.0 0.015 15.4 5.2 2.7 2 1 0 2 2 2 2 Afadin- and alpha -actinin-Binding CENP-F_leu_zip PF10473.9 OAG39400.1 - 0.0087 16.1 23.5 0.16 12.0 13.0 2.5 2 0 0 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Matrilin_ccoil PF10393.9 OAG39400.1 - 0.044 13.6 4.7 0.12 12.2 0.0 3.0 3 0 0 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin RasGAP_C PF03836.15 OAG39400.1 - 0.21 11.7 15.2 1.8 8.7 7.0 2.4 2 0 0 2 2 2 0 RasGAP C-terminus APG6_N PF17675.1 OAG39400.1 - 1.1 9.8 35.8 0.037 14.6 18.5 2.6 1 1 0 2 2 2 0 Apg6 coiled-coil region YabA PF06156.13 OAG39400.1 - 2.2 8.9 20.8 1.4 9.6 11.3 3.1 2 2 0 2 2 2 0 Initiation control protein YabA DUF641 PF04859.12 OAG39400.1 - 2.3 8.6 24.3 1.2 9.5 3.2 2.8 2 1 0 2 2 2 0 Plant protein of unknown function (DUF641) TMPIT PF07851.13 OAG39400.1 - 3 7.0 19.4 4.4 6.5 2.9 2.1 2 0 0 2 2 2 0 TMPIT-like protein ZnuA PF01297.17 OAG39400.1 - 3.4 7.0 9.8 2.1 7.7 3.3 2.1 2 0 0 2 2 2 0 Zinc-uptake complex component A periplasmic Uso1_p115_C PF04871.13 OAG39400.1 - 4.9 7.5 27.9 2.1 8.8 17.2 2.5 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Lebercilin PF15619.6 OAG39400.1 - 9.1 5.9 37.9 16 5.1 33.2 2.1 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease SlyX PF04102.12 OAG39400.1 - 9.9 6.9 31.5 0.25 12.0 2.6 4.8 2 2 3 5 5 5 0 SlyX IL31 PF15209.6 OAG39401.1 - 0.17 11.7 0.1 0.46 10.3 0.1 1.7 1 0 0 1 1 1 0 Interleukin 31 Ank_2 PF12796.7 OAG39402.1 - 8.4e-74 244.2 5.1 9.2e-11 42.2 0.0 8.0 1 1 6 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAG39402.1 - 5.6e-65 214.9 4.5 3.3e-11 43.5 0.1 9.3 5 3 4 9 9 9 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 OAG39402.1 - 1.9e-51 171.4 11.2 5.3e-08 33.0 0.1 10.8 3 2 8 11 11 11 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG39402.1 - 6.9e-51 164.3 3.3 0.001 19.4 0.1 13.4 13 1 1 14 14 14 10 Ankyrin repeat Ank PF00023.30 OAG39402.1 - 8.8e-51 168.2 8.3 6.1e-05 23.3 0.1 12.2 10 1 0 10 10 10 10 Ankyrin repeat Helo_like_N PF17111.5 OAG39402.1 - 2.2e-12 46.8 0.8 2.2e-12 46.8 0.8 1.9 2 0 0 2 2 2 1 Fungal N-terminal domain of STAND proteins NACHT PF05729.12 OAG39402.1 - 2e-08 34.3 0.0 7.1e-08 32.5 0.0 1.9 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 OAG39402.1 - 0.00023 21.6 0.1 0.0025 18.2 0.0 2.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 OAG39402.1 - 0.00027 21.2 0.0 0.0013 19.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain Elong_Iki1 PF10483.9 OAG39402.1 - 0.04 13.4 0.0 0.092 12.2 0.0 1.5 1 0 0 1 1 1 0 Elongator subunit Iki1 EutK_C PF16365.5 OAG39402.1 - 2.9 8.0 6.0 6.4 6.9 0.1 3.8 4 0 0 4 4 4 0 Ethanolamine utilization protein EutK C-terminus Metallophos PF00149.28 OAG39403.1 - 3e-07 31.2 0.1 2.1e-05 25.1 0.0 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Cation_efflux PF01545.21 OAG39404.1 - 1.5e-51 175.0 6.2 1e-50 172.3 6.2 1.9 1 1 0 1 1 1 1 Cation efflux family DUF202 PF02656.15 OAG39405.1 - 2.5e-09 37.4 0.7 2.5e-09 37.4 0.7 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF202) PIG-Y PF15159.6 OAG39405.1 - 2.4 9.1 6.2 13 6.8 6.2 2.2 1 1 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y SIR2 PF02146.17 OAG39406.1 - 1.4e-32 113.0 0.0 7.7e-32 110.6 0.0 1.9 2 0 0 2 2 2 1 Sir2 family MFS_1 PF07690.16 OAG39407.1 - 4.7e-18 65.2 22.8 6.6e-18 64.8 21.1 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily ALMT PF11744.8 OAG39408.1 - 7.9 5.2 8.8 0.13 11.1 1.1 1.7 2 0 0 2 2 2 0 Aluminium activated malate transporter DUF3273 PF11677.8 OAG39409.1 - 0.0085 15.4 1.9 0.013 14.9 1.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3273) DUF4199 PF13858.6 OAG39409.1 - 1.5 9.2 7.6 2.6 8.4 7.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) Nnf1 PF03980.14 OAG39410.1 - 2e-28 99.0 4.3 2e-28 99.0 4.3 1.8 1 1 0 1 1 1 1 Nnf1 UBN_AB PF14075.6 OAG39410.1 - 0.014 15.1 0.3 0.021 14.5 0.2 1.3 1 1 0 1 1 1 0 Ubinuclein conserved middle domain BAG6 PF12057.8 OAG39410.1 - 0.025 14.2 0.1 0.043 13.5 0.1 1.4 1 0 0 1 1 1 0 BCL2-associated athanogene 6 Metallophos_2 PF12850.7 OAG39410.1 - 0.035 14.3 0.1 0.052 13.7 0.1 1.2 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Syntaxin-6_N PF09177.11 OAG39410.1 - 0.14 12.7 2.3 0.2 12.3 1.5 1.9 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Abhydrolase_6 PF12697.7 OAG39411.1 - 9e-05 23.2 1.6 0.00019 22.1 1.6 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.11 OAG39411.1 - 0.0028 17.1 0.1 0.019 14.3 0.1 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Lipase_3 PF01764.25 OAG39411.1 - 0.0088 15.9 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) LIDHydrolase PF10230.9 OAG39411.1 - 0.0092 15.6 0.1 1.7 8.1 0.0 2.2 2 0 0 2 2 2 2 Lipid-droplet associated hydrolase Hydrolase_4 PF12146.8 OAG39411.1 - 0.022 14.0 0.0 0.046 13.0 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 OAG39411.1 - 0.17 11.8 0.0 0.17 11.8 0.0 2.4 4 0 0 4 4 4 0 alpha/beta hydrolase fold RRM_1 PF00076.22 OAG39413.1 - 1.5e-23 82.4 0.1 2.2e-23 81.8 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OAG39413.1 - 0.00043 20.3 0.0 0.00071 19.6 0.0 1.4 1 1 0 1 1 1 1 RNA recognition motif ChaC PF04752.12 OAG39414.1 - 4.2e-45 154.0 0.1 1.7e-28 99.9 0.0 2.0 1 1 1 2 2 2 2 ChaC-like protein EF-hand_6 PF13405.6 OAG39415.1 - 4.8e-15 54.1 0.6 1.7e-05 24.4 0.0 4.0 4 0 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.32 OAG39415.1 - 7.9e-13 47.0 2.4 1.2e-05 24.5 0.0 4.6 4 1 0 4 4 4 2 EF hand EF-hand_7 PF13499.6 OAG39415.1 - 3.8e-11 43.3 0.1 5.9e-07 29.8 1.7 3.1 2 2 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 OAG39415.1 - 3.7e-09 35.7 3.7 8.6e-05 21.9 0.1 3.4 3 1 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 OAG39415.1 - 1.6e-07 31.0 0.1 0.0021 17.9 0.0 3.1 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_14 PF17959.1 OAG39415.1 - 0.073 13.4 0.0 0.16 12.3 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain UCH PF00443.29 OAG39416.1 - 3.6e-55 187.2 0.0 3.6e-55 187.2 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OAG39416.1 - 9.8e-21 74.7 0.1 1.6e-13 50.9 0.0 2.5 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase YSIRK_signal PF04650.17 OAG39416.1 - 0.00033 20.4 1.6 0.00058 19.7 1.6 1.4 1 0 0 1 1 1 1 YSIRK type signal peptide PA26 PF04636.13 OAG39416.1 - 1.7 7.5 5.9 3.1 6.6 5.9 1.3 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) NusB PF01029.18 OAG39416.1 - 1.8 8.8 8.8 12 6.1 6.5 2.3 2 0 0 2 2 2 0 NusB family DUF4407 PF14362.6 OAG39416.1 - 6.8 5.9 10.1 11 5.3 10.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Yos1 PF08571.10 OAG39417.1 - 1.8e-18 66.6 0.0 2.4e-18 66.1 0.0 1.1 1 0 0 1 1 1 1 Yos1-like Cupin_2 PF07883.11 OAG39418.1 - 4.8e-08 32.6 0.1 8e-08 31.9 0.1 1.3 1 0 0 1 1 1 1 Cupin domain CDO_I PF05995.12 OAG39418.1 - 0.023 14.0 0.0 0.46 9.8 0.0 2.1 1 1 0 1 1 1 0 Cysteine dioxygenase type I Glyco_transf_22 PF03901.17 OAG39419.1 - 2e-37 129.4 20.5 2.4e-37 129.2 20.5 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Dynamitin PF04912.14 OAG39420.1 - 1.1e-59 202.8 32.2 3.1e-57 194.7 32.2 3.4 1 1 0 1 1 1 1 Dynamitin Spt20 PF12090.8 OAG39420.1 - 0.00087 19.0 7.0 0.0014 18.3 7.0 1.3 1 0 0 1 1 1 1 Spt20 family HWE_HK PF07536.14 OAG39420.1 - 0.6 10.8 13.9 5.6 7.7 2.5 4.1 2 1 2 4 4 4 0 HWE histidine kinase APG6_N PF17675.1 OAG39420.1 - 1.3 9.6 26.0 1 9.9 15.9 3.8 4 0 0 4 4 4 0 Apg6 coiled-coil region TFB6 PF17110.5 OAG39420.1 - 2.1 8.1 6.4 4.7 6.9 6.4 1.6 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Phage_Gp23 PF10669.9 OAG39420.1 - 5.1 7.5 7.6 14 6.0 7.6 1.7 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) PX PF00787.24 OAG39421.1 - 1.6e-16 60.3 1.0 5.7e-16 58.5 0.3 2.1 2 0 0 2 2 2 1 PX domain Vps5 PF09325.10 OAG39421.1 - 6.9e-13 48.7 5.9 7.5e-07 28.9 0.1 2.1 1 1 1 2 2 2 2 Vps5 C terminal like BAR PF03114.18 OAG39421.1 - 0.0046 16.6 5.6 0.084 12.5 5.6 2.3 1 1 0 1 1 1 1 BAR domain ADIP PF11559.8 OAG39421.1 - 0.0093 16.1 5.3 0.2 11.7 0.1 3.1 3 0 0 3 3 3 1 Afadin- and alpha -actinin-Binding CHAD PF05235.14 OAG39421.1 - 0.016 15.2 0.3 0.032 14.2 0.3 1.5 1 0 0 1 1 1 0 CHAD domain DASH_Dad3 PF08656.10 OAG39421.1 - 0.019 15.0 0.1 0.1 12.7 0.0 2.3 2 1 0 2 2 2 0 DASH complex subunit Dad3 Sec34 PF04136.15 OAG39421.1 - 0.028 14.3 0.0 0.1 12.5 0.0 1.9 1 1 0 1 1 1 0 Sec34-like family Spc7 PF08317.11 OAG39421.1 - 0.045 12.6 2.4 0.081 11.8 0.2 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein Occludin_ELL PF07303.13 OAG39421.1 - 0.045 14.5 3.3 0.28 11.9 0.0 3.2 4 0 0 4 4 4 0 Occludin homology domain CorA PF01544.18 OAG39422.1 - 0.0015 18.0 5.3 0.017 14.5 5.3 2.4 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein TPR_1 PF00515.28 OAG39423.1 - 2e-22 78.0 6.9 2.5e-05 23.9 0.0 6.1 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 OAG39423.1 - 8.2e-22 75.5 5.3 0.00033 20.5 0.1 6.2 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_11 PF13414.6 OAG39423.1 - 1.5e-18 66.2 4.6 1.9e-06 27.5 0.0 4.9 4 1 1 5 5 5 3 TPR repeat TPR_14 PF13428.6 OAG39423.1 - 4.9e-16 58.0 6.6 0.00011 22.7 1.2 6.0 4 1 2 6 6 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 OAG39423.1 - 8.5e-16 58.3 5.2 3.8e-06 27.5 2.3 4.2 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_17 PF13431.6 OAG39423.1 - 5.2e-15 54.7 3.4 0.013 15.8 0.2 5.3 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 OAG39423.1 - 6e-15 54.1 1.2 0.00037 20.5 0.0 5.7 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 OAG39423.1 - 6.7e-13 48.9 3.7 0.0067 16.9 0.3 4.5 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 OAG39423.1 - 4e-10 39.0 0.7 0.28 11.3 0.0 6.1 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_20 PF14561.6 OAG39423.1 - 2.2e-09 37.5 0.8 0.0024 18.2 0.1 4.1 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_9 PF13371.6 OAG39423.1 - 2.2e-09 37.3 3.0 0.00022 21.3 1.1 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 OAG39423.1 - 3.3e-09 36.9 3.1 0.77 10.1 0.3 4.4 3 1 0 4 4 4 3 Tetratricopeptide repeat ANAPC3 PF12895.7 OAG39423.1 - 2.9e-06 27.4 0.8 0.26 11.6 0.0 3.5 2 2 2 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TOM20_plant PF06552.12 OAG39423.1 - 0.00068 19.4 2.0 3.6 7.3 0.0 4.2 4 1 1 5 5 5 2 Plant specific mitochondrial import receptor subunit TOM20 TPR_15 PF13429.6 OAG39423.1 - 0.0045 16.2 0.3 0.28 10.3 0.2 2.6 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 OAG39423.1 - 0.0078 16.8 6.1 11 6.9 0.0 5.9 7 0 0 7 7 6 0 Tetratricopeptide repeat NatB_MDM20 PF09797.9 OAG39423.1 - 0.046 12.7 0.1 0.075 12.0 0.1 1.2 1 0 0 1 1 1 0 N-acetyltransferase B complex (NatB) non catalytic subunit DUF1641 PF07849.11 OAG39423.1 - 0.14 12.1 0.2 0.25 11.2 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1641) p450 PF00067.22 OAG39424.1 - 2e-55 188.4 0.0 2.4e-55 188.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 RRM_1 PF00076.22 OAG39425.1 - 2e-34 117.2 0.1 1.3e-19 69.8 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Telomere_reg-2 PF10193.9 OAG39425.1 - 4.9e-24 84.9 0.0 1.8e-23 83.1 0.0 2.0 1 0 0 1 1 1 1 Telomere length regulation protein Limkain-b1 PF11608.8 OAG39425.1 - 0.00047 20.2 0.1 0.3 11.2 0.0 2.9 2 0 0 2 2 2 2 Limkain b1 ThiF PF00899.21 OAG39426.1 - 1.9e-68 230.5 0.0 2.5e-68 230.1 0.0 1.1 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.10 OAG39426.1 - 2.2e-30 104.6 0.0 4.3e-30 103.7 0.0 1.5 1 0 0 1 1 1 1 E2 binding domain Shikimate_DH PF01488.20 OAG39426.1 - 7.5e-05 22.8 0.2 0.00022 21.3 0.0 1.9 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 OAG39426.1 - 0.063 13.5 0.2 0.71 10.1 0.1 2.6 3 0 0 3 3 3 0 Saccharopine dehydrogenase NADP binding domain Prolamin_like PF05617.11 OAG39426.1 - 0.072 13.3 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Prolamin-like Pyr_redox PF00070.27 OAG39426.1 - 0.088 13.4 0.0 0.19 12.3 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Ecm33 PF12454.8 OAG39426.1 - 0.13 12.5 2.3 0.26 11.5 2.3 1.5 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein NAD_binding_7 PF13241.6 OAG39426.1 - 0.15 12.5 0.0 0.34 11.4 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding RNA_pol_A_bac PF01000.26 OAG39427.1 - 2.2e-24 86.0 0.0 4.9e-24 84.9 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 OAG39427.1 - 2.4e-20 71.7 0.0 4.3e-20 70.9 0.0 1.4 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Complex1_49kDa PF00346.19 OAG39428.1 - 1e-123 411.8 0.0 1.4e-123 411.3 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.19 OAG39428.1 - 0.0081 15.1 0.0 0.012 14.6 0.0 1.2 1 0 0 1 1 1 1 Nickel-dependent hydrogenase Tubulin_3 PF14881.6 OAG39429.1 - 6.7e-64 214.9 1.4 1.1e-63 214.2 0.0 2.1 2 0 0 2 2 2 1 Tubulin domain Misat_Tub_SegII PF10644.9 OAG39429.1 - 4.6e-38 130.1 0.0 2.4e-37 127.8 0.0 2.3 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin PF00091.25 OAG39429.1 - 0.0027 17.9 0.0 0.24 11.6 0.0 2.3 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain TryThrA_C PF12319.8 OAG39429.1 - 0.0062 16.1 19.1 0.03 13.8 8.4 2.3 1 1 1 2 2 2 2 Tryptophan-Threonine-rich plasmodium antigen C terminal GP57 PF17594.2 OAG39429.1 - 0.077 12.8 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Phage Tail fiber assembly helper gene product 57 HSP70 PF00012.20 OAG39430.1 - 1.2e-61 208.7 2.5 6e-57 193.2 0.1 2.3 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 OAG39430.1 - 0.013 14.4 0.0 0.029 13.2 0.0 1.5 1 0 0 1 1 1 0 MreB/Mbl protein AbiEi_3_N PF17194.4 OAG39430.1 - 0.055 13.5 0.3 0.16 12.0 0.0 1.9 2 0 0 2 2 2 0 Transcriptional regulator, AbiEi antitoxin N-terminal domain HSP70 PF00012.20 OAG39431.1 - 2.5e-10 39.2 0.5 1.8e-09 36.3 0.2 1.9 2 0 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 OAG39431.1 - 0.065 12.0 0.1 0.28 10.0 0.0 1.8 2 0 0 2 2 2 0 MreB/Mbl protein Pex14_N PF04695.13 OAG39431.1 - 5 7.8 11.8 11 6.6 11.8 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region N2227 PF07942.12 OAG39432.1 - 1.8e-83 279.9 0.0 2.2e-83 279.6 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.6 OAG39432.1 - 0.025 14.4 0.0 0.061 13.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 OAG39432.1 - 0.11 13.1 0.0 9.8 6.9 0.0 2.4 1 1 0 2 2 2 0 Methyltransferase domain PAC4 PF16093.5 OAG39433.1 - 3.2e-20 72.1 0.1 4.2e-20 71.7 0.1 1.2 1 0 0 1 1 1 1 Proteasome assembly chaperone 4 POC3_POC4 PF10448.9 OAG39433.1 - 0.062 13.3 0.0 0.074 13.1 0.0 1.1 1 0 0 1 1 1 0 20S proteasome chaperone assembly proteins 3 and 4 Fungal_trans PF04082.18 OAG39434.1 - 2.9e-20 72.4 0.1 4.9e-20 71.7 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG39434.1 - 8.1e-07 29.1 13.4 1.7e-06 28.1 13.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1479 PF07350.12 OAG39435.1 - 1.1e-116 390.1 0.0 1.2e-116 389.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) Sugar_tr PF00083.24 OAG39436.1 - 1.6e-80 271.2 22.5 1.9e-80 270.9 22.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG39436.1 - 2e-21 76.3 31.4 2e-21 76.3 31.4 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_Coat_Gp8 PF05371.12 OAG39436.1 - 6.5 6.6 7.4 1.1 9.1 0.1 3.0 3 0 0 3 3 3 0 Phage major coat protein, Gp8 UPF0182 PF03699.13 OAG39436.1 - 9.2 4.3 10.3 0.86 7.7 2.2 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0182) Fungal_trans PF04082.18 OAG39437.1 - 4.2e-13 48.9 0.0 6.9e-13 48.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.18 OAG39438.1 - 8.9e-14 51.2 0.1 1.5e-13 50.4 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG39438.1 - 3.3e-05 23.9 12.4 5.8e-05 23.1 12.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Epimerase PF01370.21 OAG39439.1 - 1e-14 54.6 0.0 2.1e-14 53.6 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OAG39439.1 - 1.6e-14 53.6 0.0 2.3e-14 53.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 OAG39439.1 - 1.1e-10 41.1 0.0 0.0002 20.6 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein GDP_Man_Dehyd PF16363.5 OAG39439.1 - 1.6e-07 31.1 0.0 3.5e-07 29.9 0.0 1.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 OAG39439.1 - 2.7e-07 30.6 0.0 3.9e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 OAG39439.1 - 1.6e-06 28.2 0.0 3.7e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 OAG39439.1 - 0.0005 19.6 0.1 0.0063 16.0 0.0 2.5 3 0 0 3 3 3 1 short chain dehydrogenase Polysacc_synt_2 PF02719.15 OAG39439.1 - 0.0035 16.5 0.1 0.0077 15.4 0.0 1.5 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NmrA PF05368.13 OAG39439.1 - 0.057 13.0 0.0 0.18 11.4 0.1 1.8 2 0 0 2 2 2 0 NmrA-like family adh_short_C2 PF13561.6 OAG39439.1 - 0.06 12.9 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Glyco_hydro_47 PF01532.20 OAG39440.1 - 2.6e-112 376.0 0.0 3.8e-112 375.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Sigma70_r2 PF04542.14 OAG39440.1 - 0.25 11.1 0.6 30 4.5 0.0 3.1 3 0 0 3 3 3 0 Sigma-70 region 2 DUF2949 PF11165.8 OAG39441.1 - 0.054 13.8 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2949) KfrA_N PF11740.8 OAG39441.1 - 0.055 14.2 0.8 0.055 14.2 0.8 1.8 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term APH PF01636.23 OAG39442.1 - 1.3e-12 48.1 0.1 2.1e-12 47.5 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family DivIC PF04977.15 OAG39443.1 - 0.034 13.9 0.1 0.046 13.5 0.1 1.2 1 0 0 1 1 1 0 Septum formation initiator HTH_31 PF13560.6 OAG39443.1 - 0.07 13.5 0.1 0.11 12.9 0.1 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain Clr5 PF14420.6 OAG39444.1 - 1.2e-15 57.5 0.3 3.8e-15 55.9 0.3 1.9 1 0 0 1 1 1 1 Clr5 domain Rnk_N PF14760.6 OAG39444.1 - 0.019 15.4 0.8 13 6.3 0.0 4.3 4 0 0 4 4 4 0 Rnk N-terminus HTH_33 PF13592.6 OAG39444.1 - 0.053 13.2 0.1 0.14 11.8 0.1 1.7 1 0 0 1 1 1 0 Winged helix-turn helix F-box-like PF12937.7 OAG39446.1 - 7.5e-08 32.2 0.7 1.5e-07 31.2 0.7 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAG39446.1 - 0.00062 19.6 2.8 0.0012 18.7 2.8 1.5 1 0 0 1 1 1 1 F-box domain GalP_UDP_transf PF01087.22 OAG39447.1 - 1.5e-67 227.6 0.0 2.4e-66 223.7 0.0 2.1 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.17 OAG39447.1 - 8e-59 198.1 0.0 1.6e-58 197.1 0.0 1.4 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain HIT PF01230.23 OAG39447.1 - 0.0026 18.5 0.0 0.0064 17.2 0.0 1.7 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 OAG39447.1 - 0.017 15.6 0.0 0.036 14.6 0.0 1.5 1 0 0 1 1 1 0 Scavenger mRNA decapping enzyme C-term binding Erg28 PF03694.13 OAG39448.1 - 3.7e-36 123.9 0.4 4.4e-36 123.6 0.4 1.1 1 0 0 1 1 1 1 Erg28 like protein CrgA PF06781.12 OAG39448.1 - 0.14 12.2 3.0 0.53 10.4 0.3 2.6 1 1 2 3 3 3 0 Cell division protein CrgA adh_short PF00106.25 OAG39449.1 - 1.6e-38 132.1 0.0 2.2e-38 131.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG39449.1 - 4.4e-23 82.1 0.0 5.8e-23 81.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG39449.1 - 5e-05 23.3 0.1 0.00015 21.7 0.1 1.8 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 OAG39449.1 - 0.047 13.6 0.0 0.078 12.9 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding Ank_2 PF12796.7 OAG39450.1 - 2.2e-22 79.4 2.0 8.5e-08 32.7 0.0 3.2 2 1 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAG39450.1 - 2.5e-22 79.0 5.0 7.8e-08 32.7 0.2 5.3 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 OAG39450.1 - 2.9e-22 78.1 1.6 1.2e-06 28.6 0.0 4.5 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 OAG39450.1 - 4.8e-21 74.6 3.9 7.5e-07 29.3 0.2 4.7 3 2 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG39450.1 - 1.4e-17 61.9 2.0 0.0037 17.6 0.0 6.0 6 0 0 6 6 6 4 Ankyrin repeat AMMECR1 PF01871.17 OAG39451.1 - 8.3e-40 136.1 0.0 1.7e-39 135.1 0.0 1.4 1 0 0 1 1 1 1 AMMECR1 YL1 PF05764.13 OAG39451.1 - 0.0059 16.7 6.4 0.0085 16.2 6.4 1.2 1 0 0 1 1 1 1 YL1 nuclear protein Apt1 PF10351.9 OAG39451.1 - 0.017 14.0 4.0 0.017 14.0 4.0 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Peptidase_S64 PF08192.11 OAG39451.1 - 0.69 8.3 11.7 0.87 8.0 11.7 1.0 1 0 0 1 1 1 0 Peptidase family S64 PI3K_1B_p101 PF10486.9 OAG39451.1 - 0.77 7.5 10.2 1 7.0 10.2 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit SDA1 PF05285.12 OAG39451.1 - 1.1 8.6 12.3 1.5 8.1 12.3 1.1 1 0 0 1 1 1 0 SDA1 GREB1 PF15782.5 OAG39451.1 - 1.4 5.9 4.8 1.8 5.6 4.8 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Sporozoite_P67 PF05642.11 OAG39451.1 - 2.1 6.3 10.3 3.3 5.7 10.3 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DNA_pol_phi PF04931.13 OAG39451.1 - 2.4 6.1 8.4 3.3 5.7 8.4 1.2 1 0 0 1 1 1 0 DNA polymerase phi BUD22 PF09073.10 OAG39451.1 - 2.6 7.3 19.4 4.2 6.6 19.4 1.2 1 0 0 1 1 1 0 BUD22 Macoilin PF09726.9 OAG39451.1 - 3.8 6.0 9.3 4.8 5.6 9.3 1.0 1 0 0 1 1 1 0 Macoilin family CDC45 PF02724.14 OAG39451.1 - 3.8 5.7 8.5 4.9 5.3 8.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 OAG39451.1 - 4.2 5.5 10.7 5.3 5.1 10.7 1.0 1 0 0 1 1 1 0 Nop14-like family TFIIF_alpha PF05793.12 OAG39451.1 - 4.4 5.8 15.4 6.8 5.2 15.4 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Lin-8 PF03353.15 OAG39451.1 - 8 5.9 10.2 12 5.4 10.2 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist polyprenyl_synt PF00348.17 OAG39452.1 - 1.7e-71 240.3 0.0 8.9e-71 237.9 0.0 1.9 1 1 0 1 1 1 1 Polyprenyl synthetase HEPPP_synt_1 PF07307.11 OAG39452.1 - 0.1 12.2 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 Takusan PF04822.13 OAG39453.1 - 0.0074 16.2 1.5 0.0074 16.2 1.5 1.6 1 1 1 2 2 2 1 Takusan Helo_like_N PF17111.5 OAG39453.1 - 0.013 14.9 1.3 0.029 13.7 1.3 1.6 1 1 0 1 1 1 0 Fungal N-terminal domain of STAND proteins TPD52 PF04201.15 OAG39453.1 - 0.019 14.6 0.7 0.024 14.3 0.7 1.1 1 0 0 1 1 1 0 Tumour protein D52 family Stathmin PF00836.19 OAG39453.1 - 0.021 14.8 0.5 0.028 14.4 0.5 1.2 1 0 0 1 1 1 0 Stathmin family URO-D PF01208.17 OAG39453.1 - 0.029 13.5 0.0 0.052 12.7 0.0 1.4 2 0 0 2 2 2 0 Uroporphyrinogen decarboxylase (URO-D) CcmD PF04995.14 OAG39453.1 - 1 9.5 4.1 6.7 6.9 0.2 2.4 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) Ank_5 PF13857.6 OAG39454.1 - 1.3e-07 31.8 0.0 3e-05 24.2 0.0 3.4 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 OAG39454.1 - 8.7e-05 23.0 0.0 0.0017 18.9 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 OAG39454.1 - 0.0083 16.5 0.0 0.12 12.8 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 OAG39454.1 - 0.03 14.9 0.0 0.41 11.4 0.0 2.8 2 0 0 2 2 2 0 Ankyrin repeat PhzC-PhzF PF02567.16 OAG39455.1 - 4.5e-26 92.0 0.1 1e-22 80.9 0.0 2.2 2 0 0 2 2 2 2 Phenazine biosynthesis-like protein Fungal_trans_2 PF11951.8 OAG39455.1 - 0.033 13.0 0.2 0.063 12.1 0.2 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain p450 PF00067.22 OAG39457.1 - 2.6e-56 191.3 0.0 4.2e-56 190.6 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 DUF899 PF05988.12 OAG39458.1 - 5.2e-73 245.1 0.0 6.4e-73 244.8 0.0 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF899) Redoxin PF08534.10 OAG39458.1 - 0.019 14.7 0.0 0.033 13.9 0.0 1.3 1 0 0 1 1 1 0 Redoxin AhpC-TSA PF00578.21 OAG39458.1 - 0.048 13.6 0.0 0.08 12.9 0.0 1.3 1 0 0 1 1 1 0 AhpC/TSA family Fungal_trans_2 PF11951.8 OAG39459.1 - 0.00025 20.0 0.5 0.0005 19.0 0.1 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain MFS_1 PF07690.16 OAG39460.1 - 9.9e-35 120.1 30.3 9.9e-35 120.1 30.3 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily ThrE PF06738.12 OAG39460.1 - 0.24 10.8 10.5 1.8 7.9 0.0 3.2 3 0 0 3 3 3 0 Putative threonine/serine exporter Methyltransf_16 PF10294.9 OAG39461.1 - 1.7e-20 73.5 0.0 2.9e-20 72.7 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 OAG39461.1 - 0.00022 21.1 0.0 0.00031 20.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG39461.1 - 0.17 12.6 0.0 0.64 10.8 0.0 2.1 2 1 0 2 2 2 0 Methyltransferase domain Ribosomal_L50 PF10501.9 OAG39462.1 - 1e-06 28.8 0.1 2.4e-06 27.7 0.1 1.7 1 0 0 1 1 1 1 Ribosomal subunit 39S Thiolase_N PF00108.23 OAG39463.1 - 1.6e-74 250.5 0.3 2.2e-74 250.1 0.3 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 OAG39463.1 - 3e-41 139.9 2.0 3.2e-41 139.8 0.1 2.0 3 0 0 3 3 3 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 OAG39463.1 - 0.00056 19.6 1.6 0.0015 18.1 0.7 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Sec63 PF02889.16 OAG39465.1 - 5.6e-161 533.6 0.1 5.1e-92 307.7 0.0 2.6 3 0 0 3 3 3 2 Sec63 Brl domain DEAD PF00270.29 OAG39465.1 - 4.3e-49 166.7 0.2 4.9e-28 98.1 0.0 3.2 4 0 0 4 4 4 2 DEAD/DEAH box helicase Helicase_PWI PF18149.1 OAG39465.1 - 5.4e-31 107.0 0.8 1.9e-30 105.3 0.8 2.0 1 0 0 1 1 1 1 N-terminal helicase PWI domain ResIII PF04851.15 OAG39465.1 - 5.7e-25 88.3 0.0 2e-14 54.0 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 OAG39465.1 - 2.2e-10 40.9 0.0 1.2e-06 28.8 0.0 3.7 2 2 0 2 2 2 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 OAG39465.1 - 5.2e-08 33.2 0.0 0.00072 19.8 0.0 3.0 2 0 0 2 2 2 2 AAA domain T2SSE PF00437.20 OAG39465.1 - 0.0013 17.9 0.0 0.69 8.9 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein PhoH PF02562.16 OAG39465.1 - 0.0021 17.5 0.0 0.11 12.0 0.0 2.6 2 0 0 2 2 2 1 PhoH-like protein AAA_19 PF13245.6 OAG39465.1 - 0.025 14.9 0.2 13 6.2 0.0 3.5 3 0 0 3 3 3 0 AAA domain TFIIE_alpha PF02002.17 OAG39465.1 - 0.069 13.0 0.2 32 4.4 0.0 3.5 3 0 0 3 3 3 0 TFIIE alpha subunit Pkinase PF00069.25 OAG39466.1 - 9.6e-35 120.2 0.0 2.4e-18 66.4 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAG39466.1 - 1.4e-11 44.2 0.0 0.00078 18.8 0.0 3.8 3 1 0 3 3 3 2 Protein tyrosine kinase APH PF01636.23 OAG39466.1 - 3.9e-06 27.0 0.4 2.4e-05 24.4 0.2 2.2 2 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 OAG39466.1 - 0.093 12.3 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase PWWP PF00855.17 OAG39467.1 - 9.3e-17 61.2 0.0 9.3e-17 61.2 0.0 3.1 2 1 0 2 2 2 1 PWWP domain DNA_mis_repair PF01119.19 OAG39467.1 - 0.00042 20.0 0.0 0.015 15.0 0.0 2.3 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain Rad60-SLD PF11976.8 OAG39467.1 - 0.21 11.5 0.1 0.21 11.5 0.1 2.4 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like PAP2_3 PF14378.6 OAG39468.1 - 1.1e-31 110.0 19.1 1.9e-16 60.3 0.1 3.5 4 0 0 4 4 4 3 PAP2 superfamily PAP2 PF01569.21 OAG39468.1 - 0.046 13.5 2.3 0.064 13.0 0.2 2.3 1 1 2 3 3 3 0 PAP2 superfamily Ank_2 PF12796.7 OAG39469.1 - 3.1e-42 143.0 1.5 4.5e-09 36.8 0.0 6.1 2 1 3 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAG39469.1 - 6.4e-29 100.0 10.2 5.4e-06 26.9 0.0 7.9 5 2 2 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG39469.1 - 5e-21 72.6 3.2 1.6 9.6 0.0 11.5 11 0 0 11 11 11 5 Ankyrin repeat Ank_5 PF13857.6 OAG39469.1 - 1.3e-20 73.2 7.5 3.4e-05 24.0 0.1 8.8 4 2 5 9 9 9 6 Ankyrin repeats (many copies) Ank PF00023.30 OAG39469.1 - 1.1e-17 63.6 5.6 0.012 16.0 0.0 9.3 9 1 1 10 10 10 5 Ankyrin repeat RTC_insert PF05189.13 OAG39470.1 - 4e-31 107.6 0.0 8.6e-31 106.5 0.0 1.6 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain RTC PF01137.21 OAG39470.1 - 5e-25 88.0 0.0 6.3e-25 87.7 0.0 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase 3-HAO PF06052.12 OAG39471.1 - 2.8e-55 186.1 0.0 3.2e-55 185.9 0.0 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Auxin_BP PF02041.16 OAG39471.1 - 0.0039 16.9 0.1 0.0055 16.4 0.1 1.2 1 0 0 1 1 1 1 Auxin binding protein Cupin_2 PF07883.11 OAG39471.1 - 0.0054 16.4 0.1 0.0092 15.7 0.1 1.4 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 OAG39471.1 - 0.11 12.3 0.1 0.19 11.6 0.1 1.3 1 0 0 1 1 1 0 AraC-like ligand binding domain FAM220 PF15487.6 OAG39471.1 - 0.19 11.4 0.0 0.27 10.9 0.0 1.1 1 0 0 1 1 1 0 FAM220 family zf-RRN7 PF11781.8 OAG39471.1 - 0.25 11.0 0.8 0.43 10.3 0.8 1.4 1 0 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 MutS_V PF00488.21 OAG39472.1 - 4.4e-70 235.6 0.0 7.3e-70 234.8 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 OAG39472.1 - 4.4e-40 137.9 6.2 9.1e-40 136.9 6.2 1.6 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 OAG39472.1 - 9.7e-19 67.7 0.0 2.4e-18 66.4 0.0 1.6 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 OAG39472.1 - 3.5e-08 33.8 0.0 1.5e-07 31.8 0.0 2.0 2 0 0 2 2 2 1 MutS domain II TF_AP-2 PF03299.14 OAG39472.1 - 0.081 12.9 0.1 0.18 11.8 0.1 1.5 1 0 0 1 1 1 0 Transcription factor AP-2 AAA_29 PF13555.6 OAG39472.1 - 0.1 12.4 0.0 0.28 11.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF2046 PF09755.9 OAG39472.1 - 0.11 11.7 4.4 0.097 11.9 3.1 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein H4 (DUF2046) adh_short PF00106.25 OAG39473.1 - 2.7e-30 105.3 0.0 4e-30 104.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG39473.1 - 3.3e-17 62.8 0.1 5.8e-17 62.0 0.1 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG39473.1 - 9e-13 48.5 0.2 1.4e-12 47.9 0.2 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OAG39473.1 - 0.00012 21.3 0.1 0.00017 20.8 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Rtf2 PF04641.12 OAG39474.1 - 1.8e-58 198.0 9.4 3.3e-58 197.1 9.2 1.4 1 1 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.8 OAG39474.1 - 1.8e-08 34.1 0.0 0.0012 18.6 0.0 2.4 1 1 1 2 2 2 2 Zinc-finger of the MIZ type in Nse subunit zf-RING_5 PF14634.6 OAG39474.1 - 0.00036 20.4 0.2 0.0007 19.5 0.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 OAG39474.1 - 0.0007 19.6 2.2 0.0013 18.7 0.3 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 OAG39474.1 - 0.0079 16.5 0.6 0.013 15.8 0.1 1.6 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 OAG39474.1 - 0.02 14.7 0.5 0.043 13.7 0.5 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OAG39474.1 - 0.042 13.7 0.5 0.14 12.0 0.1 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) ADK_lid PF05191.14 OAG39474.1 - 0.064 13.3 0.9 0.44 10.6 0.3 2.5 3 0 0 3 3 3 0 Adenylate kinase, active site lid zf-NOSIP PF15906.5 OAG39474.1 - 0.14 12.3 0.0 0.33 11.1 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein Epimerase PF01370.21 OAG39475.1 - 1.5e-19 70.4 0.0 2.2e-19 69.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OAG39475.1 - 1.7e-12 47.0 0.0 2.4e-12 46.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 OAG39475.1 - 2.4e-12 46.9 0.0 5.2e-12 45.8 0.0 1.5 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 OAG39475.1 - 1.5e-09 37.4 0.0 4.3e-09 35.9 0.0 1.7 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 OAG39475.1 - 8.8e-07 29.0 0.0 1.8e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 OAG39475.1 - 0.00011 21.8 0.0 0.00048 19.6 0.0 2.2 2 1 0 2 2 2 1 short chain dehydrogenase Polysacc_synt_2 PF02719.15 OAG39475.1 - 0.0002 20.6 0.0 0.00078 18.7 0.0 1.7 1 1 1 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.10 OAG39475.1 - 0.00046 20.1 0.0 0.00083 19.3 0.0 1.4 1 0 0 1 1 1 1 KR domain NmrA PF05368.13 OAG39475.1 - 0.0027 17.3 0.0 0.061 12.9 0.0 2.2 2 0 0 2 2 2 1 NmrA-like family adh_short_C2 PF13561.6 OAG39475.1 - 0.14 11.7 0.0 0.57 9.7 0.0 1.8 1 1 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase MFS_1 PF07690.16 OAG39476.1 - 3.2e-37 128.3 48.0 3.4e-35 121.6 51.7 2.1 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF3824 PF12868.7 OAG39476.1 - 0.021 15.5 0.2 0.038 14.7 0.2 1.3 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) Zn_clus PF00172.18 OAG39477.1 - 0.02 15.0 6.2 0.04 14.1 6.2 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldedh PF00171.22 OAG39478.1 - 2.3e-157 524.2 0.1 2.6e-157 524.1 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 OAG39478.1 - 0.00011 21.7 0.0 0.14 11.6 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) LuxC PF05893.14 OAG39478.1 - 0.00037 19.7 0.0 0.00059 19.0 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) OmdA PF13376.6 OAG39478.1 - 0.11 12.6 0.8 0.24 11.4 0.8 1.5 1 0 0 1 1 1 0 Bacteriocin-protection, YdeI or OmpD-Associated ECH_1 PF00378.20 OAG39479.1 - 1.1e-72 244.4 0.1 1.4e-72 244.1 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAG39479.1 - 3.3e-35 122.2 0.2 4.7e-35 121.6 0.2 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Rer1 PF03248.13 OAG39480.1 - 7.6e-80 266.6 4.9 8.8e-80 266.4 4.9 1.0 1 0 0 1 1 1 1 Rer1 family DUF4400 PF14348.6 OAG39480.1 - 0.35 10.3 4.4 0.61 9.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4400) FAD_binding_1 PF00667.20 OAG39483.1 - 1.2e-52 178.7 0.0 1.7e-52 178.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 OAG39483.1 - 1.3e-25 90.3 0.0 2.3e-25 89.5 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 OAG39483.1 - 3.1e-19 69.6 0.1 7.3e-19 68.4 0.1 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain MFS_1 PF07690.16 OAG39485.1 - 2.3e-14 53.1 38.4 2.3e-14 53.1 38.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG39485.1 - 1.4e-05 24.1 9.2 1.4e-05 24.1 9.2 2.6 2 1 1 3 3 3 1 Sugar (and other) transporter KH_8 PF17903.1 OAG39486.1 - 2.9e-28 97.8 0.0 7.1e-28 96.5 0.0 1.7 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 OAG39486.1 - 0.042 13.7 0.0 0.11 12.3 0.0 1.8 1 0 0 1 1 1 0 KH domain DUF4746 PF15928.5 OAG39486.1 - 0.095 12.1 9.8 0.13 11.7 9.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Lon_C PF05362.13 OAG39488.1 - 3e-63 213.1 0.0 6.8e-63 211.9 0.0 1.6 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 OAG39488.1 - 2.2e-34 119.2 0.0 6.2e-34 117.7 0.0 1.8 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 OAG39488.1 - 8.4e-22 78.0 0.0 2e-21 76.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 OAG39488.1 - 1.3e-06 28.5 0.0 2.6e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 OAG39488.1 - 3.1e-06 27.4 0.0 9.5e-06 25.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) ChlI PF13541.6 OAG39488.1 - 4.3e-06 26.6 0.0 1.3e-05 25.0 0.0 1.9 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_22 PF13401.6 OAG39488.1 - 3.3e-05 24.2 0.0 0.00047 20.4 0.0 2.5 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 OAG39488.1 - 5e-05 23.1 0.0 0.00066 19.5 0.0 2.7 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_PrkA PF08298.11 OAG39488.1 - 5.5e-05 22.2 0.0 0.00011 21.3 0.0 1.4 1 0 0 1 1 1 1 PrkA AAA domain AAA_18 PF13238.6 OAG39488.1 - 0.0013 19.3 3.3 0.076 13.6 0.0 3.8 4 0 0 4 4 3 1 AAA domain AAA_16 PF13191.6 OAG39488.1 - 0.0015 18.9 3.8 0.0026 18.2 0.1 2.8 3 1 1 4 4 3 1 AAA ATPase domain SKI PF01202.22 OAG39488.1 - 0.0056 16.8 0.1 0.49 10.5 0.0 2.7 2 0 0 2 2 2 1 Shikimate kinase IstB_IS21 PF01695.17 OAG39488.1 - 0.0097 15.6 0.0 0.068 12.9 0.0 2.1 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_14 PF13173.6 OAG39488.1 - 0.019 15.0 0.0 0.053 13.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 OAG39488.1 - 0.049 13.5 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase AAA_30 PF13604.6 OAG39488.1 - 0.052 13.3 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 OAG39488.1 - 0.06 13.7 0.0 0.21 12.0 0.0 2.0 1 0 0 1 1 1 0 RNA helicase NTPase_1 PF03266.15 OAG39488.1 - 0.063 13.2 0.2 1.4 8.8 0.0 2.9 2 1 1 3 3 3 0 NTPase AAA_7 PF12775.7 OAG39488.1 - 0.11 12.0 0.6 0.24 10.9 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region DNTTIP1_dimer PF18192.1 OAG39488.1 - 0.2 12.1 2.1 3.6 8.0 0.3 3.0 2 1 0 2 2 2 0 DNTTIP1 dimerisation domain ABC_tran PF00005.27 OAG39488.1 - 0.78 10.3 4.1 0.84 10.2 0.1 2.8 3 0 0 3 3 3 0 ABC transporter DUF445 PF04286.12 OAG39488.1 - 1.3 8.8 7.1 0.57 9.9 2.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF445) DnaJ_C PF01556.18 OAG39489.1 - 1.9e-36 125.4 0.0 2.6e-36 124.9 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 OAG39489.1 - 4e-22 78.1 2.7 4e-22 78.1 2.7 1.9 2 0 0 2 2 2 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 OAG39489.1 - 3.7e-11 43.2 17.6 6.6e-11 42.4 17.6 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 OAG39489.1 - 0.94 9.5 17.1 0.14 12.1 3.1 3.3 1 1 2 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein BRO1 PF03097.18 OAG39490.1 - 1e-130 436.1 5.2 1e-130 436.1 5.2 2.4 3 0 0 3 3 3 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 OAG39490.1 - 1.9e-72 244.0 20.6 1.9e-72 244.0 20.6 1.9 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV zf-H2C2_2 PF13465.6 OAG39491.1 - 5.8e-06 26.5 10.2 2.2e-05 24.6 3.0 4.2 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2 PF00096.26 OAG39491.1 - 1.2e-05 25.5 24.5 0.00069 19.9 4.5 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 OAG39491.1 - 0.01 15.8 1.0 6.3 6.9 0.0 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OAG39491.1 - 0.02 15.2 1.4 0.11 12.8 0.2 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 OAG39491.1 - 0.027 15.3 20.4 0.048 14.5 3.0 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger FOXP-CC PF16159.5 OAG39491.1 - 0.04 14.6 2.4 0.1 13.2 0.3 2.6 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-H2C2_5 PF13909.6 OAG39491.1 - 5.2 6.9 14.2 3 7.7 0.2 3.7 3 0 0 3 3 3 0 C2H2-type zinc-finger domain FAM70 PF14967.6 OAG39491.1 - 6.9 6.0 9.9 1.1 8.6 4.0 2.0 2 0 0 2 2 2 0 FAM70 protein SAP30_Sin3_bdg PF13867.6 OAG39492.1 - 2e-08 34.4 0.0 1.1e-07 32.1 0.0 2.1 2 0 0 2 2 2 1 Sin3 binding region of histone deacetylase complex subunit SAP30 DUF4859 PF16151.5 OAG39492.1 - 0.0032 17.3 0.0 0.0076 16.1 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4859) PIG-S PF10510.9 OAG39492.1 - 0.027 13.3 1.0 0.034 13.0 1.0 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-glycan biosynthesis class S protein Pkinase_Tyr PF07714.17 OAG39493.1 - 8.6e-12 44.9 0.0 1.2e-10 41.2 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OAG39493.1 - 3.2e-11 43.1 0.0 4.6e-10 39.3 0.0 2.5 1 1 0 1 1 1 1 Protein kinase domain KIAA1328 PF15369.6 OAG39493.1 - 0.077 12.8 0.6 0.13 12.1 0.6 1.2 1 0 0 1 1 1 0 Uncharacterised protein KIAA1328 cobW PF02492.19 OAG39494.1 - 1.4e-42 145.2 0.1 3.4e-29 101.7 0.0 2.2 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 OAG39494.1 - 6.8e-05 22.7 0.0 0.00013 21.8 0.0 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain RsgA_GTPase PF03193.16 OAG39494.1 - 0.00088 19.2 0.1 0.36 10.7 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 OAG39494.1 - 0.0045 17.5 0.8 0.0081 16.7 0.8 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OAG39494.1 - 0.015 15.7 0.1 0.041 14.3 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain MMR_HSR1 PF01926.23 OAG39494.1 - 0.077 13.1 1.2 0.74 9.9 0.1 2.9 4 0 0 4 4 4 0 50S ribosome-binding GTPase TsaE PF02367.17 OAG39494.1 - 0.11 12.5 0.1 0.21 11.6 0.1 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 OAG39494.1 - 0.11 13.0 0.2 0.29 11.7 0.2 1.6 1 0 0 1 1 1 0 ABC transporter MeaB PF03308.16 OAG39494.1 - 0.12 11.4 0.6 3.6 6.5 0.0 2.8 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 OAG39494.1 - 0.13 12.5 0.0 0.46 10.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 OAG39494.1 - 0.14 11.9 1.9 0.14 11.9 0.2 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_18 PF13238.6 OAG39494.1 - 0.17 12.4 0.1 0.36 11.4 0.1 1.5 1 0 0 1 1 1 0 AAA domain Mob1_phocein PF03637.17 OAG39495.1 - 1.2e-22 80.8 0.4 1.2e-22 80.8 0.4 1.6 2 0 0 2 2 2 1 Mob1/phocein family CxC6 PF18721.1 OAG39495.1 - 0.039 14.2 4.1 0.079 13.2 4.1 1.4 1 0 0 1 1 1 0 CxC6 like cysteine cluster associated with KDZ transposases BAR_2 PF10455.9 OAG39496.1 - 2.4e-57 194.3 4.1 3.9e-57 193.6 4.1 1.3 1 1 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 OAG39496.1 - 4e-21 75.8 5.1 9.1e-15 54.9 0.7 2.1 2 0 0 2 2 2 2 BAR domain BAR_3 PF16746.5 OAG39496.1 - 0.044 13.5 1.4 0.75 9.5 0.0 2.4 2 1 0 2 2 2 0 BAR domain of APPL family Arfaptin PF06456.13 OAG39496.1 - 0.05 13.2 1.8 0.14 11.7 0.1 2.3 2 0 0 2 2 2 0 Arfaptin-like domain GCP_C_terminal PF04130.13 OAG39496.1 - 0.14 11.6 0.5 8.5 5.7 0.0 2.1 2 0 0 2 2 2 0 Gamma tubulin complex component C-terminal TFIID_20kDa PF03847.13 OAG39498.1 - 3.6e-24 85.0 0.1 5.5e-24 84.4 0.1 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A ERp29 PF07749.12 OAG39498.1 - 0.024 15.5 0.0 0.024 15.5 0.0 2.9 4 0 0 4 4 4 0 Endoplasmic reticulum protein ERp29, C-terminal domain Cdh1_DBD_1 PF18196.1 OAG39498.1 - 0.037 14.3 1.6 0.037 14.3 1.6 2.4 2 1 1 3 3 3 0 Chromodomain helicase DNA-binding domain 1 TFIID-18kDa PF02269.16 OAG39498.1 - 0.17 11.9 0.0 0.39 10.8 0.0 1.5 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit Adaptin_binding PF10199.9 OAG39498.1 - 2.1 9.0 9.9 0.2 12.2 4.6 2.0 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 DUF1744 PF08490.12 OAG39499.1 - 7.9e-149 495.6 0.8 1.3e-148 494.9 0.8 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 OAG39499.1 - 5.8e-81 272.2 0.1 9.3e-81 271.6 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 OAG39499.1 - 1.8e-16 59.9 0.1 1.8e-13 50.1 0.0 3.7 3 1 0 3 3 3 2 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 OAG39499.1 - 6e-07 29.4 0.1 2.1e-06 27.6 0.1 1.9 1 1 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 OAG39499.1 - 6.3e-05 23.0 0.1 0.00037 20.5 0.0 2.4 2 0 0 2 2 2 1 RNase_H superfamily UPF1_Zn_bind PF09416.10 OAG39499.1 - 0.013 15.5 0.5 0.072 13.1 0.0 2.6 3 0 0 3 3 3 0 RNA helicase (UPF2 interacting domain) DUF3767 PF12597.8 OAG39500.1 - 5.1e-07 29.4 0.0 8.9e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) Nop PF01798.18 OAG39502.1 - 1.9e-88 295.8 0.1 4e-88 294.8 0.1 1.6 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 OAG39502.1 - 5.3e-19 68.4 0.0 2.6e-18 66.2 0.0 2.3 1 0 0 1 1 1 1 NOP5NT (NUC127) domain DMT_YdcZ PF04657.13 OAG39502.1 - 0.052 13.8 0.1 0.088 13.1 0.1 1.2 1 0 0 1 1 1 0 Putative inner membrane exporter, YdcZ Cpn60_TCP1 PF00118.24 OAG39503.1 - 4.7e-159 530.1 0.5 5.3e-159 530.0 0.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Herpes_UL6 PF01763.16 OAG39503.1 - 0.048 12.2 0.0 0.072 11.6 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL6 like Pkinase PF00069.25 OAG39504.1 - 5.5e-55 186.6 0.0 7.4e-55 186.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG39504.1 - 7.9e-21 74.5 0.0 1.1e-20 74.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAG39504.1 - 2e-07 30.6 0.0 2.8e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OAG39504.1 - 0.00013 20.8 0.0 0.00021 20.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OAG39504.1 - 0.00052 20.0 0.1 0.00081 19.4 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 OAG39504.1 - 0.00065 19.1 0.0 0.0011 18.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family ATPase PF06745.13 OAG39505.1 - 9.1e-06 25.2 0.0 4.5e-05 22.9 0.0 2.0 2 1 0 2 2 2 1 KaiC Rad51 PF08423.11 OAG39505.1 - 3.7e-05 23.1 0.0 0.00019 20.8 0.0 2.0 1 1 0 1 1 1 1 Rad51 AAA_25 PF13481.6 OAG39505.1 - 0.00085 19.0 0.0 0.0024 17.5 0.0 1.7 2 0 0 2 2 2 1 AAA domain MeaB PF03308.16 OAG39505.1 - 0.0066 15.5 0.0 0.014 14.4 0.0 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB RecA PF00154.21 OAG39505.1 - 0.0078 15.7 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA PF00004.29 OAG39505.1 - 0.011 16.2 0.0 0.28 11.6 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DnaB_C PF03796.15 OAG39505.1 - 0.015 14.6 0.0 0.031 13.6 0.0 1.5 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain NB-ARC PF00931.22 OAG39505.1 - 0.028 13.6 0.1 1.4 8.1 0.0 2.2 1 1 1 2 2 2 0 NB-ARC domain AAA_24 PF13479.6 OAG39505.1 - 0.036 13.8 0.0 0.057 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 OAG39505.1 - 0.071 13.4 0.0 0.24 11.7 0.0 2.0 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 OAG39505.1 - 0.11 11.9 0.0 0.4 10.1 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein AAA_33 PF13671.6 OAG39505.1 - 0.53 10.4 2.1 5.3 7.2 2.1 2.2 1 1 0 1 1 1 0 AAA domain adh_short PF00106.25 OAG39506.1 - 6.9e-29 100.7 0.0 8.2e-21 74.4 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAG39506.1 - 1.4e-16 60.8 0.0 5.7e-12 45.7 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG39506.1 - 7.8e-09 35.7 0.0 1.2e-08 35.1 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 OAG39506.1 - 0.045 13.6 0.1 0.14 12.0 0.1 1.8 2 0 0 2 2 2 0 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 OAG39506.1 - 0.16 11.3 0.1 0.27 10.6 0.1 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Sugar_tr PF00083.24 OAG39509.1 - 4.8e-94 315.8 20.6 9.7e-94 314.8 20.6 1.5 1 1 1 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG39509.1 - 4.6e-14 52.1 41.3 4.8e-13 48.8 28.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ADH_N PF08240.12 OAG39510.1 - 1.6e-17 63.4 0.2 3.2e-17 62.4 0.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG39510.1 - 1.8e-16 60.3 0.0 2.7e-16 59.8 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_25 PF13649.6 OAG39510.1 - 0.0041 17.8 0.8 0.029 15.1 0.8 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG39510.1 - 0.0097 16.5 0.1 0.035 14.8 0.1 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG39510.1 - 0.01 15.7 0.2 0.018 14.8 0.2 1.5 1 1 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 OAG39510.1 - 0.067 12.7 0.1 0.11 12.0 0.1 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 Prot_ATP_ID_OB PF16450.5 OAG39510.1 - 0.16 11.9 0.0 2.5 8.1 0.0 2.4 2 0 0 2 2 2 0 Proteasomal ATPase OB C-terminal domain Methyltransf_12 PF08242.12 OAG39510.1 - 0.22 12.3 0.4 1.8 9.3 0.4 2.3 1 1 0 1 1 1 0 Methyltransferase domain DAO PF01266.24 OAG39511.1 - 7.1e-05 22.5 0.0 0.00011 22.0 0.0 1.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAG39511.1 - 0.0008 19.6 0.1 0.0035 17.5 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 OAG39511.1 - 0.0011 18.3 0.0 0.0015 17.8 0.0 1.2 1 0 0 1 1 1 1 Thi4 family adh_short PF00106.25 OAG39511.1 - 0.047 13.2 0.0 0.057 12.9 0.0 1.2 1 0 0 1 1 1 0 short chain dehydrogenase HECW1_helix PF18436.1 OAG39511.1 - 0.073 13.2 0.1 0.2 11.8 0.0 1.7 2 0 0 2 2 2 0 Helical box domain of E3 ubiquitin-protein ligase HECW1 ApbA PF02558.16 OAG39511.1 - 0.086 12.5 0.0 0.088 12.4 0.0 1.1 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.6 OAG39511.1 - 0.15 11.3 0.0 0.19 10.9 0.0 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 OAG39511.1 - 0.19 11.8 0.0 0.25 11.4 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Abhydrolase_6 PF12697.7 OAG39512.1 - 1.2e-12 48.9 7.1 1.5e-12 48.6 7.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAG39512.1 - 3e-11 43.5 0.6 4.4e-11 42.9 0.6 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAG39512.1 - 2.8e-05 23.5 0.1 3.8e-05 23.1 0.1 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 OAG39512.1 - 0.083 12.5 0.5 0.1 12.3 0.5 1.4 1 1 0 1 1 1 0 Putative esterase Amidohydro_1 PF01979.20 OAG39513.1 - 0.025 13.9 0.0 0.027 13.8 0.0 1.1 1 0 0 1 1 1 0 Amidohydrolase family MFS_1 PF07690.16 OAG39514.1 - 1.5e-37 129.4 28.2 2.1e-37 128.9 28.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Trp_oprn_chp PF09534.10 OAG39514.1 - 0.05 13.4 0.1 0.75 9.6 0.0 2.2 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Hum_adeno_E3A PF05393.11 OAG39514.1 - 0.11 12.5 0.3 2.9 7.9 0.0 2.4 2 0 0 2 2 2 0 Human adenovirus early E3A glycoprotein Phage_holin_3_3 PF16083.5 OAG39514.1 - 6 7.1 12.7 0.39 10.9 0.4 3.2 4 0 0 4 4 4 0 LydA holin phage, holin superfamily III ADH_zinc_N PF00107.26 OAG39515.1 - 1.5e-24 86.4 0.7 2e-24 86.0 0.1 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAG39515.1 - 1.7e-16 61.5 0.0 5.3e-16 59.9 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG39515.1 - 4.3e-08 33.0 0.0 1.3e-07 31.5 0.0 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.18 OAG39515.1 - 0.025 14.8 0.0 0.047 14.0 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain AlaDh_PNT_C PF01262.21 OAG39515.1 - 0.039 13.3 0.1 0.062 12.6 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DUF5423 PF17461.2 OAG39515.1 - 0.12 11.2 0.1 0.19 10.5 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5423) PEP_mutase PF13714.6 OAG39516.1 - 2.4e-44 151.6 1.8 2.8e-44 151.4 1.8 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 OAG39516.1 - 3.1e-16 59.0 0.4 4.2e-16 58.5 0.4 1.2 1 0 0 1 1 1 1 Isocitrate lyase family Pantoate_transf PF02548.15 OAG39516.1 - 0.011 15.2 0.1 0.023 14.1 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate hydroxymethyltransferase 6PGD PF00393.19 OAG39516.1 - 0.035 13.5 0.0 0.054 12.9 0.0 1.2 1 0 0 1 1 1 0 6-phosphogluconate dehydrogenase, C-terminal domain Cupin_2 PF07883.11 OAG39517.1 - 1.3e-08 34.4 0.0 2.4e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Cupin domain DIOX_N PF14226.6 OAG39518.1 - 8.2e-19 68.5 0.0 1.6e-18 67.5 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OAG39518.1 - 3.8e-13 49.8 0.0 7.8e-13 48.8 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF4473 PF14747.6 OAG39518.1 - 0.038 14.6 0.0 1.1 9.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4473) MmgE_PrpD PF03972.14 OAG39519.1 - 6.5e-52 176.5 0.1 8.2e-52 176.2 0.1 1.0 1 0 0 1 1 1 1 MmgE/PrpD family YitT_membrane PF02588.15 OAG39519.1 - 0.15 11.4 0.1 0.45 9.8 0.1 1.8 2 0 0 2 2 2 0 Uncharacterised 5xTM membrane BCR, YitT family COG1284 FAD_binding_4 PF01565.23 OAG39521.1 - 3.3e-17 62.5 0.0 5e-17 61.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain FixP_N PF14715.6 OAG39522.1 - 8.2 6.3 12.9 0.77 9.6 0.2 3.7 3 0 0 3 3 3 0 N-terminal domain of cytochrome oxidase-cbb3, FixP MFS_1 PF07690.16 OAG39523.1 - 9.1e-37 126.8 25.2 9.1e-37 126.8 25.2 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily WD40_4 PF16300.5 OAG39523.1 - 2.8e-19 68.7 0.1 5.3e-19 67.8 0.1 1.5 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 OAG39523.1 - 3.5e-12 46.6 0.9 0.00048 20.9 0.1 4.6 4 0 0 4 4 4 2 WD domain, G-beta repeat DUF1899 PF08953.11 OAG39523.1 - 4e-11 42.6 0.1 1.5e-10 40.8 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1899) MFS_4 PF06779.14 OAG39523.1 - 4e-06 26.4 5.6 4e-06 26.4 5.6 1.7 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB ANAPC4_WD40 PF12894.7 OAG39523.1 - 1.4e-05 25.3 0.0 0.0035 17.6 0.0 2.9 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain DUF1230 PF06799.11 OAG39523.1 - 0.023 14.8 0.4 0.023 14.8 0.4 1.9 2 0 0 2 2 2 0 Conserved in the green lineage and diatoms 27 BRE1 PF08647.11 OAG39523.1 - 0.12 12.4 0.4 0.25 11.4 0.4 1.5 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase Nup160 PF11715.8 OAG39523.1 - 0.18 10.4 0.1 0.54 8.8 0.1 1.7 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Fib_alpha PF08702.10 OAG39523.1 - 0.21 11.8 0.6 0.36 11.0 0.2 1.6 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family FlaC_arch PF05377.11 OAG39523.1 - 0.46 10.9 1.2 1.1 9.7 1.2 1.6 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Peptidase_M20 PF01546.28 OAG39524.1 - 4.1e-30 105.0 0.5 6.8e-30 104.3 0.2 1.5 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.17 OAG39524.1 - 0.062 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M28 M20_dimer PF07687.14 OAG39524.1 - 0.074 13.0 0.0 0.2 11.6 0.0 1.8 1 0 0 1 1 1 0 Peptidase dimerisation domain Zn_clus PF00172.18 OAG39525.1 - 4.7e-07 29.8 5.6 1.2e-06 28.5 5.6 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.25 OAG39526.1 - 2.1e-21 76.5 0.0 3.6e-21 75.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG39526.1 - 2.1e-17 63.3 0.0 4.8e-17 62.1 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_2 PF12796.7 OAG39526.1 - 3.4e-15 56.4 0.2 5.4e-05 23.7 0.0 4.9 3 2 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAG39526.1 - 2.7e-14 53.3 2.1 0.00015 22.2 0.0 6.5 2 2 3 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG39526.1 - 2.6e-11 42.7 0.3 0.6 10.8 0.0 7.1 7 0 0 7 7 7 3 Ankyrin repeat Ank_5 PF13857.6 OAG39526.1 - 1.6e-09 37.8 1.4 6.6e-08 32.7 0.1 3.8 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank PF00023.30 OAG39526.1 - 7.9e-05 22.9 7.2 6.2 7.5 0.0 7.2 8 0 0 8 8 8 2 Ankyrin repeat Kdo PF06293.14 OAG39526.1 - 0.089 12.1 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HeLo PF14479.6 OAG39527.1 - 4.7e-11 42.9 0.0 7.5e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Prion-inhibition and propagation Pkinase_Tyr PF07714.17 OAG39527.1 - 0.00069 19.0 0.0 0.14 11.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 OAG39527.1 - 0.014 14.8 0.0 0.076 12.4 0.0 1.9 1 1 0 1 1 1 0 Protein kinase domain ADH_N PF08240.12 OAG39528.1 - 1.4e-19 69.9 1.6 2.8e-19 69.0 1.6 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG39528.1 - 4.8e-16 58.9 0.0 1.1e-15 57.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 OAG39528.1 - 0.02 14.2 0.0 0.061 12.6 0.0 1.7 1 1 1 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Methyltransf_31 PF13847.6 OAG39528.1 - 0.12 12.1 0.0 0.25 11.1 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain ADH_zinc_N_2 PF13602.6 OAG39528.1 - 0.2 12.7 0.0 0.68 11.0 0.0 1.8 1 1 1 2 2 2 0 Zinc-binding dehydrogenase Rubredoxin_2 PF18073.1 OAG39528.1 - 3.1 7.6 7.7 7.1 6.4 4.6 2.6 2 1 0 2 2 2 0 Rubredoxin metal binding domain NAD_binding_2 PF03446.15 OAG39529.1 - 1.1e-27 97.1 0.0 1.7e-27 96.5 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 OAG39529.1 - 2.2e-18 66.7 0.0 3.4e-18 66.0 0.0 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 OAG39529.1 - 0.021 15.4 0.0 0.061 13.9 0.0 1.9 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent MFS_1 PF07690.16 OAG39530.1 - 1.9e-34 119.1 59.1 2e-34 119.1 57.5 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 OAG39530.1 - 2.6e-13 49.3 12.5 4e-13 48.7 12.5 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 OAG39530.1 - 2e-10 40.1 9.7 2e-10 40.1 9.7 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter Phage_holin_3_1 PF05106.12 OAG39530.1 - 1.5 9.3 5.8 0.43 11.0 1.4 2.4 2 0 0 2 2 2 0 Phage holin family (Lysis protein S) zf-C3HC4 PF00097.25 OAG39532.1 - 2.5e-07 30.4 6.9 2.5e-07 30.4 6.9 4.7 4 2 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OAG39532.1 - 8e-07 28.8 4.0 8e-07 28.8 4.0 4.9 7 1 1 8 8 7 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAG39532.1 - 1.1e-05 25.7 6.9 1.1e-05 25.7 6.9 4.8 5 1 0 5 5 3 1 Ring finger domain zf-RING_UBOX PF13445.6 OAG39532.1 - 1.6e-05 24.8 5.8 1.6e-05 24.8 5.8 3.7 4 0 0 4 4 4 1 RING-type zinc-finger zf-RING_6 PF14835.6 OAG39532.1 - 6.5e-05 22.7 1.0 6.5e-05 22.7 1.0 3.0 3 0 0 3 3 1 1 zf-RING of BARD1-type protein zf-RING_5 PF14634.6 OAG39532.1 - 0.0002 21.3 5.8 0.0002 21.3 5.8 4.7 6 0 0 6 6 4 1 zinc-RING finger domain SH3_9 PF14604.6 OAG39532.1 - 0.0066 16.3 0.2 0.0066 16.3 0.2 2.4 2 0 0 2 2 2 1 Variant SH3 domain zf-C3HC4_4 PF15227.6 OAG39532.1 - 0.0077 16.4 7.8 0.0077 16.4 7.8 3.8 3 1 1 4 4 3 1 zinc finger of C3HC4-type, RING SH3_1 PF00018.28 OAG39532.1 - 0.027 14.1 0.1 0.066 12.8 0.1 1.6 1 0 0 1 1 1 0 SH3 domain SH3_2 PF07653.17 OAG39532.1 - 0.047 13.4 1.0 0.086 12.5 0.1 1.9 2 0 0 2 2 2 0 Variant SH3 domain C1_2 PF03107.16 OAG39532.1 - 0.92 9.9 0.0 0.92 9.9 0.0 5.0 5 1 0 5 5 5 0 C1 domain Sugar_tr PF00083.24 OAG39533.1 - 4e-108 362.2 22.9 4.8e-108 361.9 22.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG39533.1 - 3.7e-28 98.5 30.8 1.1e-25 90.3 23.5 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Acetyltransf_1 PF00583.25 OAG39534.1 - 1.9e-10 41.0 0.1 4.7e-09 36.5 0.1 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OAG39534.1 - 4.4e-10 39.8 0.0 7.5e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OAG39534.1 - 6.2e-08 32.6 0.0 1.3e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 OAG39534.1 - 0.00062 19.9 0.0 0.0027 17.8 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain EBP PF05241.12 OAG39535.1 - 1.5e-63 213.5 2.9 1.8e-63 213.2 2.9 1.0 1 0 0 1 1 1 1 Emopamil binding protein Fungal_trans PF04082.18 OAG39536.1 - 3e-10 39.6 1.5 5.4e-10 38.7 1.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG39536.1 - 1.5e-05 25.0 13.2 2.5e-05 24.3 13.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short_C2 PF13561.6 OAG39537.1 - 4.1e-56 190.2 0.0 1.5e-54 185.1 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG39537.1 - 1.1e-40 139.1 0.0 2.8e-40 137.9 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG39537.1 - 2.9e-14 53.4 0.0 4.7e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG39537.1 - 0.00068 19.2 0.0 0.0015 18.1 0.0 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 OAG39537.1 - 0.0011 18.2 0.0 0.0015 17.7 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 OAG39537.1 - 0.032 14.5 0.0 0.055 13.7 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Peptidase_M48 PF01435.18 OAG39538.1 - 3.4e-32 111.8 0.0 5.3e-32 111.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 PRCC PF10253.9 OAG39539.1 - 5.6e-37 128.6 10.1 5.6e-37 128.6 10.1 2.4 1 1 1 2 2 2 1 Mitotic checkpoint regulator, MAD2B-interacting DUF1957 PF09210.11 OAG39540.1 - 0.086 13.3 0.1 0.14 12.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1957) AAA_5 PF07728.14 OAG39541.1 - 1.9e-122 403.7 0.0 1.8e-22 79.8 0.0 9.6 9 0 0 9 9 9 9 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 OAG39541.1 - 7.4e-44 148.3 6.0 5.5e-16 58.7 0.0 5.9 6 0 0 6 6 4 4 Midasin AAA lid domain AAA_3 PF07726.11 OAG39541.1 - 3e-31 108.0 0.0 4.3e-12 46.0 0.0 7.5 8 0 0 8 8 7 3 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 OAG39541.1 - 1.1e-29 103.2 0.1 7.8e-06 25.5 0.0 7.1 7 0 0 7 7 7 6 P-loop containing dynein motor region AAA_lid_5 PF17865.1 OAG39541.1 - 1.1e-28 99.4 0.8 1.4e-26 92.7 0.1 3.4 4 0 0 4 4 2 1 Midasin AAA lid domain AAA PF00004.29 OAG39541.1 - 3.3e-28 98.8 0.0 4.4e-05 23.9 0.0 6.9 6 0 0 6 6 6 5 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OAG39541.1 - 4.1e-23 82.6 23.8 0.0014 19.1 0.1 10.2 10 1 0 10 10 7 6 AAA ATPase domain Dynein_heavy PF03028.15 OAG39541.1 - 5.1e-21 75.0 0.0 0.00058 19.9 0.0 6.9 6 0 0 6 6 6 5 Dynein heavy chain region D6 P-loop domain AAA_18 PF13238.6 OAG39541.1 - 3.3e-20 73.0 0.9 0.00013 22.5 0.0 7.2 6 0 0 6 6 6 4 AAA domain AAA_6 PF12774.7 OAG39541.1 - 1.8e-18 66.6 0.0 0.011 14.7 0.0 7.9 8 0 0 8 8 7 4 Hydrolytic ATP binding site of dynein motor region TsaE PF02367.17 OAG39541.1 - 1.3e-16 60.7 0.0 0.31 11.0 0.0 6.7 6 0 0 6 6 6 4 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 OAG39541.1 - 2.3e-16 60.3 0.1 0.0085 16.4 0.0 7.5 7 0 0 7 7 6 2 AAA domain Sigma54_activat PF00158.26 OAG39541.1 - 1.4e-15 57.4 0.0 0.02 14.6 0.0 6.9 7 0 0 7 7 6 3 Sigma-54 interaction domain ABC_tran PF00005.27 OAG39541.1 - 1.8e-14 54.4 0.1 0.15 12.5 0.0 7.5 7 0 0 7 7 7 3 ABC transporter AAA_14 PF13173.6 OAG39541.1 - 3.8e-14 52.9 0.0 0.089 12.8 0.0 7.5 7 0 0 7 7 7 3 AAA domain AAA_33 PF13671.6 OAG39541.1 - 6.3e-14 52.3 0.3 0.051 13.7 0.0 7.9 7 0 0 7 7 7 2 AAA domain AAA_30 PF13604.6 OAG39541.1 - 2.4e-12 47.0 0.0 0.77 9.4 0.0 7.2 6 1 0 6 6 6 2 AAA domain T2SSE PF00437.20 OAG39541.1 - 5.8e-12 45.2 0.2 0.017 14.2 0.0 6.3 6 0 0 6 6 6 2 Type II/IV secretion system protein RsgA_GTPase PF03193.16 OAG39541.1 - 6.8e-12 45.6 0.4 0.082 12.8 0.0 6.2 6 0 0 6 6 6 2 RsgA GTPase RNA_helicase PF00910.22 OAG39541.1 - 1.3e-11 44.8 0.6 3.5 8.1 0.0 6.8 6 0 0 6 6 6 0 RNA helicase NACHT PF05729.12 OAG39541.1 - 1.6e-11 44.4 1.5 0.41 10.5 0.1 6.4 6 0 0 6 6 5 3 NACHT domain Mg_chelatase PF01078.21 OAG39541.1 - 2.3e-11 43.5 0.2 3.4 7.0 0.0 9.5 10 0 0 10 10 10 0 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 OAG39541.1 - 3.2e-11 43.2 0.1 0.43 10.3 0.0 6.4 6 0 0 6 6 6 2 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activ_2 PF14532.6 OAG39541.1 - 8e-11 42.2 0.0 0.018 15.2 0.0 6.0 5 0 0 5 5 5 1 Sigma-54 interaction domain Zeta_toxin PF06414.12 OAG39541.1 - 6.9e-10 38.5 0.1 0.83 8.9 0.0 6.9 6 0 0 6 6 6 1 Zeta toxin AAA_29 PF13555.6 OAG39541.1 - 1.3e-09 37.7 0.1 1 9.2 0.0 6.3 6 0 0 6 6 6 2 P-loop containing region of AAA domain AAA_28 PF13521.6 OAG39541.1 - 8.8e-09 35.8 1.8 0.092 13.0 0.0 6.5 6 0 0 6 6 6 1 AAA domain IstB_IS21 PF01695.17 OAG39541.1 - 1.3e-08 34.8 0.0 0.96 9.2 0.0 5.8 6 0 0 6 6 5 1 IstB-like ATP binding protein AAA_19 PF13245.6 OAG39541.1 - 4.1e-08 33.7 0.7 5 7.5 0.0 6.1 5 0 0 5 5 5 0 AAA domain Rad17 PF03215.15 OAG39541.1 - 1.5e-07 31.5 0.4 0.23 11.4 0.0 5.9 6 0 0 6 6 6 1 Rad17 P-loop domain AAA_25 PF13481.6 OAG39541.1 - 2.2e-07 30.6 1.2 0.92 9.0 0.0 5.6 5 0 0 5 5 5 1 AAA domain MCM PF00493.23 OAG39541.1 - 2.8e-07 29.9 0.0 5.8 5.9 0.0 6.4 6 0 0 6 6 6 0 MCM P-loop domain ATPase_2 PF01637.18 OAG39541.1 - 3.7e-07 30.3 0.0 1.3 8.9 0.0 5.4 6 0 0 6 6 5 2 ATPase domain predominantly from Archaea PduV-EutP PF10662.9 OAG39541.1 - 8.7e-07 28.8 0.2 0.71 9.6 0.0 5.1 6 0 0 6 6 4 1 Ethanolamine utilisation - propanediol utilisation DUF815 PF05673.13 OAG39541.1 - 1.1e-06 28.0 0.6 2 7.5 0.0 5.6 6 0 0 6 6 6 2 Protein of unknown function (DUF815) Roc PF08477.13 OAG39541.1 - 1.7e-06 28.3 1.8 5.9 7.1 0.1 6.2 6 0 0 6 6 6 0 Ras of Complex, Roc, domain of DAPkinase NTPase_1 PF03266.15 OAG39541.1 - 5.4e-06 26.4 2.7 3.3 7.6 0.3 5.5 5 0 0 5 5 5 0 NTPase TniB PF05621.11 OAG39541.1 - 2.2e-05 23.9 0.0 21 4.5 0.0 5.9 6 0 0 6 6 6 0 Bacterial TniB protein TIP49 PF06068.13 OAG39541.1 - 3e-05 23.4 0.2 0.046 12.9 0.0 4.7 6 0 0 6 6 6 1 TIP49 P-loop domain AAA_24 PF13479.6 OAG39541.1 - 4.6e-05 23.2 0.0 2 8.1 0.0 5.4 6 0 0 6 6 6 1 AAA domain MMR_HSR1 PF01926.23 OAG39541.1 - 0.00015 21.8 1.5 28 4.8 0.0 6.1 6 0 0 6 6 5 0 50S ribosome-binding GTPase PhoH PF02562.16 OAG39541.1 - 0.00027 20.4 0.2 2.1 7.8 0.0 4.4 5 0 0 5 5 5 1 PhoH-like protein SRP54 PF00448.22 OAG39541.1 - 0.00043 20.0 1.2 11 5.5 0.1 4.8 5 0 0 5 5 5 0 SRP54-type protein, GTPase domain dNK PF01712.19 OAG39541.1 - 0.00058 19.8 3.2 3.6 7.4 0.0 5.0 5 0 0 5 5 4 0 Deoxynucleoside kinase AAA_8 PF12780.7 OAG39541.1 - 0.00064 19.1 0.0 22 4.2 0.0 5.9 6 0 0 6 6 6 0 P-loop containing dynein motor region D4 Bac_DnaA PF00308.18 OAG39541.1 - 0.00073 19.4 0.0 3.5 7.4 0.0 4.3 4 0 0 4 4 4 0 Bacterial dnaA protein cobW PF02492.19 OAG39541.1 - 0.00074 19.1 1.2 1 8.9 0.0 4.6 5 0 0 5 5 4 1 CobW/HypB/UreG, nucleotide-binding domain CPT PF07931.12 OAG39541.1 - 0.00078 19.3 2.2 1.7 8.5 0.0 5.5 5 1 0 5 5 4 1 Chloramphenicol phosphotransferase-like protein Cytidylate_kin PF02224.18 OAG39541.1 - 0.001 18.9 0.6 1.6 8.4 0.0 3.8 3 0 0 3 3 3 1 Cytidylate kinase CbiA PF01656.23 OAG39541.1 - 0.0014 18.7 0.0 2.5 8.2 0.0 3.9 3 0 0 3 3 3 1 CobQ/CobB/MinD/ParA nucleotide binding domain FtsK_SpoIIIE PF01580.18 OAG39541.1 - 0.0025 17.2 0.1 2.7 7.3 0.0 4.4 6 0 0 6 6 4 1 FtsK/SpoIIIE family SRPRB PF09439.10 OAG39541.1 - 0.0073 15.7 0.2 13 5.2 0.0 4.9 6 0 0 6 6 6 0 Signal recognition particle receptor beta subunit Viral_helicase1 PF01443.18 OAG39541.1 - 0.0076 16.0 0.0 7.1 6.3 0.0 4.6 5 0 0 5 5 4 0 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.22 OAG39541.1 - 0.0081 15.4 0.1 22 4.1 0.0 4.7 5 0 0 5 5 5 0 NB-ARC domain ATP_bind_1 PF03029.17 OAG39541.1 - 0.013 15.3 10.6 5.8 6.6 0.1 5.4 6 0 0 6 6 4 0 Conserved hypothetical ATP binding protein AAA_21 PF13304.6 OAG39541.1 - 0.046 13.5 1.1 1.5 8.6 0.0 3.9 4 1 0 4 4 3 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF4924 PF16271.5 OAG39541.1 - 0.12 12.4 0.0 0.68 9.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4924) Rad51 PF08423.11 OAG39541.1 - 0.14 11.4 0.0 9.2 5.4 0.0 2.7 2 0 0 2 2 2 0 Rad51 KTI12 PF08433.10 OAG39541.1 - 0.15 11.5 0.0 48 3.3 0.0 3.7 3 0 0 3 3 3 0 Chromatin associated protein KTI12 PH_10 PF15411.6 OAG39542.1 - 6.2e-25 87.8 0.1 1.1e-24 87.0 0.1 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain VWA PF00092.28 OAG39542.1 - 2.4e-13 50.7 0.0 4.1e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 OAG39542.1 - 5.2e-07 29.7 0.1 3.9e-06 26.9 0.1 2.3 1 1 0 1 1 1 1 von Willebrand factor type A domain zf-RING_2 PF13639.6 OAG39542.1 - 6.4e-05 23.2 3.0 0.00012 22.3 3.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 OAG39542.1 - 0.00039 20.3 3.8 0.00077 19.4 3.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 OAG39542.1 - 0.00076 19.1 3.0 0.0015 18.1 3.0 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_2 PF13923.6 OAG39542.1 - 0.00088 19.1 3.3 0.0018 18.0 3.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.11 OAG39542.1 - 0.00094 19.4 3.9 0.0016 18.7 3.9 1.4 1 0 0 1 1 1 1 RING-like domain zf-C3HC4 PF00097.25 OAG39542.1 - 0.0015 18.4 3.3 0.003 17.4 3.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OAG39542.1 - 0.018 15.3 1.3 0.04 14.2 1.3 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain PH PF00169.29 OAG39542.1 - 0.11 13.1 0.0 0.25 11.9 0.0 1.6 1 0 0 1 1 1 0 PH domain Prok-RING_4 PF14447.6 OAG39542.1 - 0.26 11.2 2.4 0.46 10.4 2.4 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 OAG39542.1 - 0.67 10.0 3.4 1.6 8.8 3.4 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3H2C3 PF17122.5 OAG39542.1 - 0.74 9.9 4.2 2 8.5 4.2 1.8 1 1 0 1 1 1 0 Zinc-finger Arm_vescicular PF18770.1 OAG39543.1 - 0.13 12.2 0.1 0.37 10.7 0.1 1.7 1 0 0 1 1 1 0 Armadillo tether-repeat of vescicular transport factor Voltage_CLC PF00654.20 OAG39544.1 - 2.8e-87 293.3 33.2 8.7e-87 291.6 31.9 1.9 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 OAG39544.1 - 0.001 19.5 0.0 2.6 8.6 0.0 2.6 2 0 0 2 2 2 2 CBS domain Cpn60_TCP1 PF00118.24 OAG39545.1 - 3.7e-150 500.8 9.3 4.2e-150 500.6 9.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family RXT2_N PF08595.11 OAG39545.1 - 0.0056 16.7 3.3 0.013 15.5 3.3 1.6 1 0 0 1 1 1 1 RXT2-like, N-terminal FAM176 PF14851.6 OAG39545.1 - 0.016 14.9 2.9 0.036 13.7 2.9 1.5 1 0 0 1 1 1 0 FAM176 family Pox_Ag35 PF03286.14 OAG39545.1 - 0.02 14.7 2.2 0.047 13.5 2.2 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein TetR_C_14 PF17754.1 OAG39545.1 - 0.036 14.0 0.9 5.8 6.9 0.1 2.5 2 0 0 2 2 2 0 MftR C-terminal domain EAL PF00563.20 OAG39545.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 EAL domain TFB6 PF17110.5 OAG39545.1 - 0.14 11.9 2.1 0.41 10.4 2.1 1.8 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Sporozoite_P67 PF05642.11 OAG39545.1 - 0.25 9.4 4.4 0.42 8.6 4.4 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Nucleo_P87 PF07267.11 OAG39545.1 - 0.28 10.0 1.5 0.52 9.1 1.5 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 NOA36 PF06524.12 OAG39545.1 - 0.81 9.0 11.0 1.3 8.3 11.0 1.2 1 0 0 1 1 1 0 NOA36 protein Sigma70_ner PF04546.13 OAG39545.1 - 1.3 8.9 6.3 0.49 10.2 3.0 1.8 2 0 0 2 2 2 0 Sigma-70, non-essential region Nop14 PF04147.12 OAG39545.1 - 1.5 6.9 7.2 2.1 6.4 7.2 1.1 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 OAG39545.1 - 3.6 5.6 11.9 6.7 4.7 11.9 1.3 1 0 0 1 1 1 0 DNA polymerase phi DUF2457 PF10446.9 OAG39545.1 - 4.1 6.4 11.7 6.7 5.7 11.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) HMG_box PF00505.19 OAG39546.1 - 0.00045 20.6 0.4 0.00081 19.8 0.4 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box PLN_propep PF16485.5 OAG39546.1 - 0.14 11.9 1.0 4.3 7.1 0.1 2.4 2 0 0 2 2 2 0 Protealysin propeptide MDMPI_N PF11716.8 OAG39546.1 - 9.4 6.9 7.5 2.7 8.7 3.5 2.1 2 0 0 2 2 2 0 Mycothiol maleylpyruvate isomerase N-terminal domain DUF4238 PF14022.6 OAG39549.1 - 2.7e-44 151.7 1.1 3.5e-44 151.4 1.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4238) Vps62 PF06101.11 OAG39550.1 - 6.8e-15 54.4 1.1 1.3e-14 53.4 0.3 1.9 2 0 0 2 2 2 1 Vacuolar protein sorting-associated protein 62 Haspin_kinase PF12330.8 OAG39552.1 - 2.2e-33 115.7 0.0 3.3e-33 115.1 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Nucleoside_tran PF01733.18 OAG39553.1 - 2.2e-51 175.1 7.0 3.5e-51 174.4 7.0 1.3 1 0 0 1 1 1 1 Nucleoside transporter MFS_1 PF07690.16 OAG39553.1 - 1.7e-08 33.8 30.2 0.00022 20.3 5.6 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily SKG6 PF08693.10 OAG39554.1 - 0.0071 15.7 1.0 0.015 14.7 1.0 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF347 PF03988.12 OAG39554.1 - 0.027 14.6 0.1 0.027 14.6 0.1 1.4 2 0 0 2 2 2 0 Repeat of Unknown Function (DUF347) ABC1 PF03109.16 OAG39555.1 - 4.1e-22 78.6 0.0 1.1e-21 77.2 0.0 1.7 1 0 0 1 1 1 1 ABC1 family CobW_C PF07683.14 OAG39555.1 - 0.046 13.7 0.1 0.18 11.8 0.1 2.0 2 0 0 2 2 2 0 Cobalamin synthesis protein cobW C-terminal domain Annexin PF00191.20 OAG39556.1 - 4.6e-16 58.6 0.2 0.00092 19.2 0.1 4.6 4 0 0 4 4 4 4 Annexin ArgoL1 PF08699.10 OAG39556.1 - 0.15 11.7 0.0 0.37 10.5 0.0 1.6 1 0 0 1 1 1 0 Argonaute linker 1 domain adh_short_C2 PF13561.6 OAG39557.1 - 2.8e-50 171.1 0.0 3.6e-50 170.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG39557.1 - 9.8e-35 119.8 0.0 2e-34 118.8 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 OAG39557.1 - 0.00015 21.8 0.1 0.00046 20.1 0.1 1.9 1 1 0 1 1 1 1 KR domain GTP_EFTU PF00009.27 OAG39558.1 - 9e-55 185.2 0.0 1.4e-54 184.6 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 OAG39558.1 - 5e-42 142.7 0.0 1.1e-41 141.6 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 OAG39558.1 - 3.4e-14 53.0 1.6 3.4e-14 53.0 1.6 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 TFIIS_C PF01096.18 OAG39558.1 - 3.3e-11 42.8 0.2 3.3e-11 42.8 0.2 2.6 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) MMR_HSR1 PF01926.23 OAG39558.1 - 0.0018 18.3 0.1 0.036 14.2 0.1 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase RNA_POL_M_15KD PF02150.16 OAG39558.1 - 0.17 11.8 7.2 0.67 9.9 7.2 1.9 1 1 0 1 1 1 0 RNA polymerases M/15 Kd subunit GTP_EFTU_D4 PF14578.6 OAG39558.1 - 0.83 9.6 4.0 0.38 10.7 1.0 2.0 2 0 0 2 2 2 0 Elongation factor Tu domain 4 Ank_2 PF12796.7 OAG39559.1 - 3.1e-11 43.7 0.1 2.5e-05 24.8 0.1 1.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OAG39559.1 - 1e-08 35.2 0.1 0.23 11.8 0.1 3.8 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG39559.1 - 5.8e-07 29.3 0.1 0.055 14.0 0.1 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 OAG39559.1 - 0.0044 17.6 0.0 0.019 15.5 0.0 2.1 3 0 0 3 3 3 1 Ankyrin repeats (many copies) GAT PF03127.14 OAG39559.1 - 0.0071 16.6 0.1 0.027 14.8 0.0 1.9 2 0 0 2 2 2 1 GAT domain Ank PF00023.30 OAG39559.1 - 0.0085 16.5 0.0 3.6 8.2 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat MFS_1 PF07690.16 OAG39560.1 - 3.1e-51 174.4 57.4 3.3e-51 174.3 56.0 1.7 2 1 0 2 2 2 1 Major Facilitator Superfamily Ferric_reduct PF01794.19 OAG39561.1 - 5.3e-21 75.0 11.1 5.3e-21 75.0 11.1 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 OAG39561.1 - 9.6e-14 51.4 0.0 2.2e-07 30.9 0.0 2.4 2 0 0 2 2 2 2 FAD-binding domain NAD_binding_6 PF08030.12 OAG39561.1 - 1.3e-13 51.4 0.3 5.6e-11 42.8 0.2 2.7 2 1 0 2 2 2 1 Ferric reductase NAD binding domain ATP-synt_I PF03899.15 OAG39561.1 - 0.015 15.7 2.4 0.015 15.7 2.4 3.2 4 0 0 4 4 4 0 ATP synthase I chain Aldolase_II PF00596.21 OAG39562.1 - 4.4e-51 173.5 0.4 5.6e-51 173.1 0.4 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain BRO1 PF03097.18 OAG39563.1 - 9.3e-117 390.1 0.2 1.1e-115 386.5 0.0 2.2 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 OAG39563.1 - 6.2e-85 285.1 14.4 6.2e-85 285.1 14.4 1.7 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV DUF4770 PF15994.5 OAG39563.1 - 1.4 9.2 4.7 16 5.6 0.4 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4770) Vac7 PF12751.7 OAG39564.1 - 0.11 11.9 0.1 0.14 11.6 0.1 1.1 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 Sigma_reg_N PF13800.6 OAG39564.1 - 0.13 12.5 0.1 0.19 12.1 0.1 1.2 1 0 0 1 1 1 0 Sigma factor regulator N-terminal Herpes_US9 PF06072.11 OAG39564.1 - 0.22 11.4 1.4 0.53 10.2 1.4 1.6 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 SNARE PF05739.19 OAG39564.1 - 0.6 10.2 4.4 0.56 10.2 2.4 1.8 2 0 0 2 2 2 0 SNARE domain Fungal_trans_2 PF11951.8 OAG39565.1 - 0.0053 15.6 0.0 0.026 13.4 0.0 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain bZIP_1 PF00170.21 OAG39566.1 - 4.6e-07 29.8 11.4 4.6e-07 29.8 11.4 1.7 1 1 1 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 OAG39566.1 - 7.8e-05 22.7 19.2 0.00037 20.5 11.1 2.2 1 1 1 2 2 2 2 Basic region leucine zipper SlyX PF04102.12 OAG39566.1 - 0.00025 21.6 4.8 0.00025 21.6 4.8 1.6 1 1 0 1 1 1 1 SlyX bZIP_Maf PF03131.17 OAG39566.1 - 0.00053 20.4 11.3 0.00087 19.8 11.3 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor Spc29 PF17082.5 OAG39566.1 - 0.0034 17.3 1.9 0.0072 16.2 1.8 1.6 1 1 0 1 1 1 1 Spindle Pole Component 29 Herpes_UL25 PF01499.16 OAG39566.1 - 0.042 12.4 6.1 0.057 11.9 6.1 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family Nup54 PF13874.6 OAG39566.1 - 0.078 13.1 7.4 0.12 12.5 7.4 1.2 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 LMBR1 PF04791.16 OAG39566.1 - 0.093 11.6 1.6 0.1 11.5 1.6 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein JIP_LZII PF16471.5 OAG39566.1 - 0.13 12.4 3.1 0.46 10.7 3.1 1.9 1 1 0 1 1 1 0 JNK-interacting protein leucine zipper II Phasin PF05597.11 OAG39566.1 - 0.17 11.9 4.1 0.26 11.3 4.1 1.3 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DivIC PF04977.15 OAG39566.1 - 0.59 9.9 11.6 0.13 12.0 2.4 2.2 1 1 1 2 2 2 0 Septum formation initiator Spc7 PF08317.11 OAG39566.1 - 0.62 8.9 8.5 0.94 8.3 8.5 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Med9 PF07544.13 OAG39566.1 - 0.91 9.7 5.6 1.7 8.8 5.6 1.6 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Shugoshin_N PF07558.11 OAG39566.1 - 1.4 8.9 8.6 3.8 7.5 1.2 2.6 2 1 1 3 3 3 0 Shugoshin N-terminal coiled-coil region FAD_binding_3 PF01494.19 OAG39568.1 - 1.5e-23 83.6 0.0 6.7e-23 81.5 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 OAG39568.1 - 5.9e-08 32.8 1.4 1.3e-07 31.7 0.7 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAG39568.1 - 6.5e-08 32.5 9.3 0.0019 17.9 5.9 2.7 1 1 2 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG39568.1 - 2.1e-07 30.5 2.0 6.4e-06 25.6 2.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 OAG39568.1 - 1.3e-06 28.1 0.8 1.9e-06 27.5 0.8 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 OAG39568.1 - 3e-06 26.2 1.6 0.00042 19.2 2.6 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 OAG39568.1 - 3.1e-06 27.6 0.2 0.0004 20.9 0.3 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAG39568.1 - 3.9e-06 26.2 6.8 3.9e-06 26.2 6.8 1.5 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.22 OAG39568.1 - 0.0003 20.0 5.0 0.0021 17.2 6.2 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 OAG39568.1 - 0.00033 20.0 1.0 0.0036 16.6 1.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 OAG39568.1 - 0.00094 18.3 0.0 0.0014 17.7 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase Thi4 PF01946.17 OAG39568.1 - 0.0021 17.3 2.1 0.0034 16.6 2.1 1.2 1 0 0 1 1 1 1 Thi4 family Trp_halogenase PF04820.14 OAG39568.1 - 0.0025 16.7 4.6 0.75 8.6 0.0 2.1 1 1 0 2 2 2 2 Tryptophan halogenase Amino_oxidase PF01593.24 OAG39568.1 - 0.0046 16.3 0.8 0.094 12.0 0.8 2.6 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase Rossmann-like PF10727.9 OAG39568.1 - 0.0073 16.2 2.7 0.024 14.5 1.0 2.4 3 0 0 3 3 3 1 Rossmann-like domain 3HCDH_N PF02737.18 OAG39568.1 - 0.032 14.1 2.6 0.054 13.4 2.6 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 OAG39568.1 - 0.084 12.2 3.4 0.16 11.2 3.4 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain MCRA PF06100.11 OAG39568.1 - 0.15 10.8 0.5 0.3 9.8 0.5 1.4 2 0 0 2 2 2 0 MCRA family NAD_Gly3P_dh_N PF01210.23 OAG39568.1 - 0.21 11.6 0.2 0.34 10.9 0.2 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UDPG_MGDP_dh_N PF03721.14 OAG39568.1 - 0.28 10.7 0.2 0.43 10.1 0.2 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Lycopene_cycl PF05834.12 OAG39568.1 - 0.41 9.7 2.0 1.8 7.5 2.7 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein Aa_trans PF01490.18 OAG39569.1 - 1.2e-45 155.9 33.2 1.4e-45 155.8 33.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein HMGL-like PF00682.19 OAG39570.1 - 1.7e-75 254.0 0.0 3.2e-75 253.1 0.0 1.5 1 0 0 1 1 1 1 HMGL-like DAO PF01266.24 OAG39570.1 - 7.2e-51 173.8 0.1 1.7e-50 172.6 0.1 1.7 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 OAG39570.1 - 7.3e-44 148.7 0.1 1.5e-43 147.7 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase LeuA_dimer PF08502.10 OAG39570.1 - 3.8e-22 78.6 0.3 1.5e-21 76.7 0.3 2.0 1 1 0 1 1 1 1 LeuA allosteric (dimerisation) domain FAD_binding_2 PF00890.24 OAG39570.1 - 4.4e-08 32.6 0.7 1.6e-07 30.8 0.7 1.9 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 OAG39570.1 - 2.2e-05 24.0 0.3 0.00017 21.1 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG39570.1 - 0.0008 18.7 0.1 0.0034 16.7 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG39570.1 - 0.0041 17.3 0.8 0.018 15.3 0.2 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.18 OAG39570.1 - 0.013 15.4 1.2 0.023 14.6 0.2 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.22 OAG39570.1 - 0.019 14.0 0.4 0.055 12.5 0.4 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A HI0933_like PF03486.14 OAG39570.1 - 0.078 11.7 0.4 0.14 10.8 0.4 1.3 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.27 OAG39570.1 - 0.19 12.3 2.1 0.38 11.3 0.1 2.7 4 0 0 4 4 2 0 Pyridine nucleotide-disulphide oxidoreductase TRAPP PF04051.16 OAG39573.1 - 1.8e-34 118.5 0.0 2.3e-34 118.2 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component DUF4250 PF14056.6 OAG39573.1 - 0.061 13.3 0.1 0.12 12.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4250) WD40 PF00400.32 OAG39574.1 - 1.4e-38 130.2 11.0 4.8e-07 30.4 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG39574.1 - 3.5e-10 40.0 0.1 0.4 11.0 0.0 4.9 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 OAG39574.1 - 0.0058 15.4 0.1 1 8.0 0.0 2.3 2 0 0 2 2 2 2 Nup133 N terminal like Ge1_WD40 PF16529.5 OAG39574.1 - 0.064 12.2 0.0 9.4 5.1 0.0 2.5 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF2207 PF09972.9 OAG39576.1 - 0.12 11.1 0.0 0.17 10.7 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) HSD3 PF15244.6 OAG39576.1 - 0.27 10.7 2.7 0.54 9.7 2.7 1.4 1 0 0 1 1 1 0 Spermatogenesis-associated protein 7, or HSD3 DUF3382 PF11862.8 OAG39576.1 - 0.29 11.4 1.9 0.31 11.3 0.7 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3382) 7TM_GPCR_Srab PF10292.9 OAG39576.1 - 2.3 7.0 5.2 3.3 6.5 5.2 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR receptor class ab chemoreceptor Phytase-like PF13449.6 OAG39577.1 - 1.3e-37 130.3 0.0 2.1e-37 129.6 0.0 1.3 1 0 0 1 1 1 1 Esterase-like activity of phytase LVIVD PF08309.11 OAG39577.1 - 0.12 11.7 4.9 0.61 9.4 0.4 3.4 4 0 0 4 4 4 0 LVIVD repeat RskA PF10099.9 OAG39578.1 - 0.02 15.2 0.0 0.043 14.1 0.0 1.5 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Zip PF02535.22 OAG39578.1 - 0.041 13.1 2.4 0.015 14.5 0.6 1.5 2 0 0 2 2 2 0 ZIP Zinc transporter Peroxin-3 PF04882.12 OAG39578.1 - 0.073 12.1 3.7 0.07 12.1 2.4 1.7 2 1 0 2 2 2 0 Peroxin-3 SET PF00856.28 OAG39579.1 - 7e-13 49.3 0.0 1.6e-12 48.1 0.0 1.6 1 0 0 1 1 1 1 SET domain Glyoxalase PF00903.25 OAG39580.1 - 4.5e-12 46.3 0.0 7.4e-12 45.6 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 OAG39580.1 - 1.1e-10 41.7 0.0 2.2e-10 40.8 0.0 1.5 1 1 1 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 OAG39580.1 - 0.023 14.6 0.0 0.19 11.6 0.0 2.2 2 1 0 2 2 2 0 Glyoxalase-like domain DUF1674 PF07896.12 OAG39581.1 - 8.2e-20 71.0 3.8 2.2e-19 69.7 3.2 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1674) Aminotran_3 PF00202.21 OAG39583.1 - 3.9e-111 371.6 0.0 5e-111 371.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III DUF3185 PF11381.8 OAG39583.1 - 0.022 14.8 0.0 0.07 13.2 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3185) Aminotran_1_2 PF00155.21 OAG39583.1 - 0.038 13.2 0.0 0.07 12.3 0.0 1.6 1 1 0 1 1 1 0 Aminotransferase class I and II DUF1989 PF09347.10 OAG39584.1 - 1.4e-63 213.5 0.0 1.8e-63 213.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) Zn_clus PF00172.18 OAG39585.1 - 5.8e-08 32.7 7.8 5.8e-08 32.7 7.8 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Beta-lactamase PF00144.24 OAG39586.1 - 6.4e-42 144.0 1.5 1.2e-41 143.0 1.5 1.4 1 0 0 1 1 1 1 Beta-lactamase MtrC PF04211.13 OAG39587.1 - 0.051 12.6 0.8 4.9 6.1 0.0 2.1 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit C HET PF06985.11 OAG39588.1 - 2.4e-13 50.7 0.0 5.9e-13 49.4 0.0 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Trp_syntA PF00290.20 OAG39590.1 - 8.5e-94 313.2 0.0 1.4e-93 312.5 0.0 1.3 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.25 OAG39590.1 - 1.6e-50 172.2 1.1 2.8e-50 171.4 1.1 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF1308 PF07000.11 OAG39590.1 - 0.18 11.7 0.1 0.9 9.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1308) TRI5 PF06330.11 OAG39591.1 - 1.8e-18 66.5 0.0 2.8e-18 66.0 0.0 1.2 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) adh_short_C2 PF13561.6 OAG39592.1 - 4.7e-55 186.7 4.1 5.8e-55 186.4 4.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG39592.1 - 1.3e-44 152.0 1.2 1.7e-44 151.6 1.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG39592.1 - 1.8e-05 24.7 0.1 3.1e-05 24.0 0.1 1.4 1 0 0 1 1 1 1 KR domain SWIRM-assoc_3 PF16498.5 OAG39592.1 - 0.0046 17.2 1.4 0.019 15.2 0.3 2.2 2 0 0 2 2 2 1 SWIRM-associated domain at the C-terminal Methyltransf_25 PF13649.6 OAG39592.1 - 0.011 16.4 0.0 0.022 15.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain NAD_binding_10 PF13460.6 OAG39592.1 - 0.18 11.7 2.5 0.33 10.8 2.4 1.5 1 1 0 1 1 1 0 NAD(P)H-binding Sugar_tr PF00083.24 OAG39593.1 - 1.5e-78 264.7 24.7 1.8e-78 264.5 24.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG39593.1 - 9.4e-21 74.1 46.0 1.2e-13 50.8 17.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Acyl-CoA_dh_1 PF00441.24 OAG39595.1 - 2.5e-29 102.5 0.9 3.3e-29 102.0 0.9 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 OAG39595.1 - 8.6e-19 67.5 0.1 1.6e-18 66.7 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 OAG39595.1 - 4.1e-14 53.2 0.0 1.2e-13 51.6 0.0 1.8 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Aldo_ket_red PF00248.21 OAG39596.1 - 2.3e-73 247.0 0.0 2.7e-73 246.7 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Coatomer_E PF04733.14 OAG39597.1 - 5.8e-54 183.5 9.9 6.6e-54 183.3 10.0 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.6 OAG39597.1 - 2.4e-05 24.8 23.2 0.001 19.5 2.3 4.1 4 1 0 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 OAG39597.1 - 0.00012 22.2 0.9 0.4 10.9 0.0 2.9 2 1 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 OAG39597.1 - 0.00048 20.7 16.9 0.014 16.0 0.2 4.2 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 OAG39597.1 - 0.0031 17.5 4.3 0.14 12.3 0.0 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 OAG39597.1 - 0.01 15.6 0.5 1.9 8.4 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 OAG39597.1 - 0.019 15.1 0.6 0.17 12.2 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 OAG39597.1 - 0.032 14.5 11.2 0.22 11.8 0.2 4.4 1 1 1 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 OAG39597.1 - 0.12 13.1 0.6 0.12 13.1 0.6 5.4 6 1 0 6 6 5 0 Tetratricopeptide repeat Type_III_YscG PF09477.10 OAG39597.1 - 0.13 12.4 5.4 1 9.4 2.0 2.6 1 1 0 2 2 2 0 Bacterial type II secretion system chaperone protein (type_III_yscG) TPR_6 PF13174.6 OAG39597.1 - 0.21 12.3 5.1 5.2 7.9 0.1 4.2 5 0 0 5 5 3 0 Tetratricopeptide repeat ANAPC5 PF12862.7 OAG39597.1 - 3.5 7.8 6.6 1.1 9.4 0.1 3.1 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 5 DUF3425 PF11905.8 OAG39598.1 - 2.5e-23 82.4 3.4 4.5e-23 81.6 3.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 OAG39598.1 - 0.0028 17.7 9.1 0.0055 16.8 7.0 2.2 1 1 1 2 2 2 1 bZIP transcription factor DUF429 PF04250.13 OAG39598.1 - 0.087 12.6 0.5 0.16 11.8 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF429) COG5 PF10392.9 OAG39598.1 - 0.23 11.7 1.8 0.52 10.5 1.8 1.5 1 0 0 1 1 1 0 Golgi transport complex subunit 5 bZIP_2 PF07716.15 OAG39598.1 - 1 9.5 10.5 0.069 13.2 4.6 1.9 2 0 0 2 2 2 0 Basic region leucine zipper BMFP PF04380.13 OAG39598.1 - 4.7 7.8 8.2 2 9.0 1.4 2.6 3 0 0 3 3 3 0 Membrane fusogenic activity LRR_8 PF13855.6 OAG39599.1 - 0.55 10.0 3.1 11 5.8 0.6 3.2 3 0 0 3 3 3 0 Leucine rich repeat tRNA-synt_1 PF00133.22 OAG39600.1 - 1.8e-43 148.7 0.0 4.2e-25 88.0 0.0 5.7 2 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.6 OAG39600.1 - 6.7e-39 133.3 0.0 1.1e-38 132.7 0.0 1.3 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.11 OAG39600.1 - 1.2e-27 96.7 0.2 1.5e-19 70.0 0.0 4.2 3 1 1 4 4 4 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 OAG39600.1 - 2.7e-09 37.1 0.0 5.4e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 OAG39600.1 - 0.0034 16.8 0.0 1.4 8.1 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Ank_2 PF12796.7 OAG39602.1 - 9.1e-39 131.9 4.6 9.9e-13 48.5 0.1 6.3 1 1 4 6 6 6 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OAG39602.1 - 3.4e-31 106.9 8.1 2.2e-09 37.4 0.2 7.4 5 1 2 7 7 7 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 OAG39602.1 - 2.6e-25 88.5 11.9 9.5e-07 29.3 0.3 7.6 5 1 2 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG39602.1 - 8.9e-20 68.7 9.4 0.0053 17.2 0.0 9.6 9 1 0 9 9 9 4 Ankyrin repeat Ank PF00023.30 OAG39602.1 - 2.1e-17 62.7 6.9 0.00061 20.1 0.0 8.1 8 0 0 8 8 8 3 Ankyrin repeat NACHT PF05729.12 OAG39602.1 - 2.5e-09 37.2 0.0 9.9e-09 35.3 0.0 2.0 2 0 0 2 2 2 1 NACHT domain AAA PF00004.29 OAG39602.1 - 0.0059 17.0 0.0 0.02 15.3 0.0 2.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OAG39602.1 - 0.014 15.8 0.0 0.096 13.1 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 OAG39602.1 - 0.048 13.9 0.0 0.16 12.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 OAG39602.1 - 0.076 12.3 0.0 0.2 10.9 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin NB-ARC PF00931.22 OAG39602.1 - 0.077 12.2 0.1 0.26 10.5 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain Rx_N PF18052.1 OAG39602.1 - 0.21 11.9 0.7 0.58 10.5 0.4 1.8 1 1 0 1 1 1 0 Rx N-terminal domain GIDA PF01134.22 OAG39603.1 - 4e-156 520.0 0.0 4.8e-156 519.8 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 OAG39603.1 - 2.5e-65 220.6 0.0 3.5e-65 220.1 0.0 1.2 1 0 0 1 1 1 1 GidA associated domain FAD_oxidored PF12831.7 OAG39603.1 - 4.4e-08 32.9 0.4 8e-08 32.0 0.4 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG39603.1 - 3.2e-06 26.6 0.4 8.9e-06 25.1 0.4 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAG39603.1 - 0.00021 20.5 1.5 0.00046 19.4 1.5 1.6 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 OAG39603.1 - 0.0067 15.8 0.3 0.013 14.8 0.3 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 OAG39603.1 - 0.037 12.7 3.1 0.14 10.8 0.5 2.4 3 0 0 3 3 3 0 HI0933-like protein K_oxygenase PF13434.6 OAG39603.1 - 0.15 11.1 0.0 0.41 9.7 0.0 1.6 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 OAG39603.1 - 0.2 10.9 0.0 0.57 9.4 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase CDP-OH_P_transf PF01066.21 OAG39604.1 - 1.8e-13 51.0 1.0 1.8e-13 51.0 1.0 2.2 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Sec1 PF00995.23 OAG39605.1 - 1e-132 444.4 0.3 1.2e-132 444.1 0.3 1.1 1 0 0 1 1 1 1 Sec1 family B12-binding PF02310.19 OAG39605.1 - 0.12 12.4 0.1 0.35 10.9 0.1 1.7 1 0 0 1 1 1 0 B12 binding domain MBOAT PF03062.19 OAG39606.1 - 1.5e-57 195.6 3.6 3.2e-57 194.5 3.6 1.5 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Gti1_Pac2 PF09729.9 OAG39608.1 - 2.1e-63 213.7 0.0 4.7e-63 212.6 0.0 1.6 1 0 0 1 1 1 1 Gti1/Pac2 family Tyr-DNA_phospho PF06087.12 OAG39609.1 - 5.1e-55 187.1 0.0 5e-34 117.9 0.0 2.2 2 0 0 2 2 2 2 Tyrosyl-DNA phosphodiesterase UIM PF02809.20 OAG39609.1 - 0.0021 17.9 3.8 0.0021 17.9 3.8 2.1 2 0 0 2 2 2 1 Ubiquitin interaction motif SARAF PF06682.12 OAG39610.1 - 2.5e-97 326.5 0.7 3e-97 326.2 0.7 1.0 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis cNMP_binding PF00027.29 OAG39611.1 - 2.7e-29 101.1 2.4 9.1e-18 64.1 0.0 5.6 6 0 0 6 6 6 4 Cyclic nucleotide-binding domain Patatin PF01734.22 OAG39611.1 - 3.4e-17 63.3 5.2 1.7e-16 61.0 4.3 2.7 2 1 0 2 2 2 1 Patatin-like phospholipase Amidohydro_1 PF01979.20 OAG39612.1 - 2.7e-69 234.1 0.0 3.1e-69 233.9 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 OAG39612.1 - 1.7e-06 27.8 0.4 0.00059 19.4 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family SGIII PF15467.6 OAG39612.1 - 0.01 15.1 0.0 0.013 14.8 0.0 1.1 1 0 0 1 1 1 0 Secretogranin-3 A_deaminase PF00962.22 OAG39612.1 - 0.064 12.6 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Adenosine/AMP deaminase TIMELESS PF04821.14 OAG39613.1 - 1.8e-83 280.0 0.0 4.4e-83 278.7 0.0 1.8 1 0 0 1 1 1 1 Timeless protein TIMELESS_C PF05029.13 OAG39613.1 - 7e-32 111.3 19.0 7e-32 111.3 19.0 4.2 2 1 1 3 3 3 1 Timeless protein C terminal region 3HCDH_N PF02737.18 OAG39614.1 - 5.1e-53 179.6 1.7 6.7e-53 179.2 1.7 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 OAG39614.1 - 1.6e-33 115.2 0.0 3.9e-33 113.9 0.0 1.7 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Sacchrp_dh_NADP PF03435.18 OAG39614.1 - 0.00013 22.3 0.1 0.00023 21.4 0.1 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_2 PF03446.15 OAG39614.1 - 0.00068 19.8 0.5 0.0026 17.9 0.4 1.9 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase UDPG_MGDP_dh_N PF03721.14 OAG39614.1 - 0.0045 16.6 0.5 0.038 13.6 0.5 2.0 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox_2 PF07992.14 OAG39614.1 - 0.0062 15.8 0.0 0.0082 15.4 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 OAG39614.1 - 0.009 15.4 0.2 0.046 13.1 0.2 2.0 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DAO PF01266.24 OAG39614.1 - 0.061 12.9 0.1 0.095 12.3 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 OAG39614.1 - 0.13 12.8 0.0 0.28 11.8 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase EI24 PF07264.11 OAG39615.1 - 3.2e-10 40.5 0.1 5.4e-09 36.5 0.1 2.1 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) adh_short_C2 PF13561.6 OAG39617.1 - 6.1e-48 163.4 0.0 6.9e-48 163.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG39617.1 - 1.2e-40 139.0 0.3 1.4e-40 138.8 0.3 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG39617.1 - 2.7e-10 40.5 0.1 4.6e-10 39.7 0.1 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG39617.1 - 4.8e-05 22.9 0.0 0.00054 19.5 0.0 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 OAG39617.1 - 0.093 11.8 0.0 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain HHH_5 PF14520.6 OAG39617.1 - 0.19 12.3 0.6 0.35 11.5 0.6 1.4 1 0 0 1 1 1 0 Helix-hairpin-helix domain DUF3333 PF11812.8 OAG39619.1 - 0.075 13.2 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3333) p450 PF00067.22 OAG39620.1 - 1.2e-59 202.3 0.0 1.5e-59 202.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pirin_C_2 PF17954.1 OAG39621.1 - 0.051 13.7 0.0 0.08 13.1 0.0 1.3 1 0 0 1 1 1 0 Quercetinase C-terminal cupin domain Inp1 PF12634.7 OAG39622.1 - 1.8e-35 121.9 0.1 8.5e-35 119.7 0.0 2.2 2 0 0 2 2 2 1 Inheritance of peroxisomes protein 1 SRP14 PF02290.15 OAG39623.1 - 3.2e-25 88.3 1.7 3.2e-25 88.3 1.7 1.8 2 1 0 2 2 2 1 Signal recognition particle 14kD protein MIF4G PF02854.19 OAG39624.1 - 3.9e-22 78.9 4.7 6.3e-22 78.3 4.7 1.3 1 0 0 1 1 1 1 MIF4G domain MA3 PF02847.17 OAG39624.1 - 9.2e-18 64.3 0.8 3.9e-17 62.2 0.0 2.5 3 0 0 3 3 3 1 MA3 domain SOG2 PF10428.9 OAG39625.1 - 0.031 13.5 0.1 0.036 13.3 0.1 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein adh_short_C2 PF13561.6 OAG39626.1 - 6.7e-37 127.3 0.6 9.2e-37 126.8 0.6 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG39626.1 - 1.2e-36 126.1 0.1 1.6e-36 125.6 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG39626.1 - 2.5e-08 34.0 0.4 4.4e-08 33.2 0.4 1.3 1 0 0 1 1 1 1 KR domain Prenyltransf PF01255.19 OAG39626.1 - 0.021 14.3 0.0 0.032 13.8 0.0 1.2 1 0 0 1 1 1 0 Putative undecaprenyl diphosphate synthase Amidase PF01425.21 OAG39626.1 - 0.032 13.2 0.4 0.057 12.4 0.1 1.5 2 0 0 2 2 2 0 Amidase Kelch_4 PF13418.6 OAG39627.1 - 8.3e-24 83.3 5.2 5.2e-10 39.2 0.0 6.6 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_3 PF13415.6 OAG39627.1 - 8.7e-19 67.3 2.3 0.00065 19.9 0.0 6.6 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_6 PF13964.6 OAG39627.1 - 3.7e-15 55.6 2.6 0.00058 20.1 0.1 5.7 5 1 1 6 6 6 5 Kelch motif Kelch_1 PF01344.25 OAG39627.1 - 1.4e-11 43.8 0.2 0.00098 18.7 0.0 5.7 6 0 0 6 6 6 3 Kelch motif Kelch_2 PF07646.15 OAG39627.1 - 1e-08 34.8 7.3 0.002 18.0 0.4 5.8 6 1 0 6 6 6 3 Kelch motif Kelch_5 PF13854.6 OAG39627.1 - 6e-07 29.3 0.4 0.39 10.8 0.0 5.2 5 0 0 5 5 5 2 Kelch motif PQQ_3 PF13570.6 OAG39627.1 - 0.012 16.1 2.1 4.2 8.0 0.1 4.1 4 1 0 4 4 4 0 PQQ-like domain TFIIA_gamma_C PF02751.14 OAG39627.1 - 0.49 10.6 1.7 36 4.6 0.0 3.4 4 0 0 4 4 4 0 Transcription initiation factor IIA, gamma subunit NACHT PF05729.12 OAG39628.1 - 5.5e-10 39.4 0.0 1.7e-09 37.8 0.0 1.9 1 0 0 1 1 1 1 NACHT domain TPR_12 PF13424.6 OAG39628.1 - 3.8e-08 33.5 25.0 0.023 15.0 0.3 9.9 10 1 1 11 11 11 4 Tetratricopeptide repeat AAA_16 PF13191.6 OAG39628.1 - 1.8e-06 28.5 0.0 9e-06 26.2 0.0 2.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OAG39628.1 - 1.1e-05 25.7 0.1 9.6e-05 22.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain TPR_19 PF14559.6 OAG39628.1 - 0.00013 22.4 0.1 2.8 8.5 0.0 5.1 4 1 0 4 4 4 1 Tetratricopeptide repeat AAA PF00004.29 OAG39628.1 - 0.0099 16.3 0.2 0.15 12.5 0.0 3.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 OAG39628.1 - 0.011 14.8 0.0 0.029 13.4 0.0 1.7 1 0 0 1 1 1 0 Type II/IV secretion system protein TPR_7 PF13176.6 OAG39628.1 - 0.055 13.5 3.7 14 6.0 0.0 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat ACT PF01842.25 OAG39628.1 - 0.25 11.1 2.3 2 8.3 0.1 3.1 3 0 0 3 3 3 0 ACT domain TPR_10 PF13374.6 OAG39628.1 - 7 6.7 9.5 60 3.7 0.1 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat AA_permease PF00324.21 OAG39629.1 - 1.7e-139 465.5 41.2 2e-139 465.3 41.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAG39629.1 - 1.7e-37 129.3 47.8 2.4e-37 128.8 47.8 1.2 1 0 0 1 1 1 1 Amino acid permease NAD_binding_8 PF13450.6 OAG39630.1 - 5.1e-14 52.2 0.3 3.6e-13 49.5 0.2 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAG39630.1 - 1.1e-08 35.1 0.0 6.3e-08 32.6 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG39630.1 - 9.8e-06 25.0 0.0 2.1e-05 23.9 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAG39630.1 - 0.00017 20.8 0.0 0.00028 20.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.24 OAG39630.1 - 0.00039 19.8 0.2 0.047 13.0 0.0 3.1 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 OAG39630.1 - 0.00041 20.4 0.0 0.0043 17.1 0.0 2.5 3 0 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.17 OAG39630.1 - 0.0022 17.3 0.0 0.0037 16.5 0.0 1.2 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 OAG39630.1 - 0.0067 15.2 0.0 0.019 13.7 0.0 1.6 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 OAG39630.1 - 0.0085 16.6 0.0 1.8 9.2 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 OAG39630.1 - 0.032 13.5 0.0 0.08 12.2 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.12 OAG39630.1 - 0.047 12.7 0.0 0.072 12.1 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_7 PF13241.6 OAG39630.1 - 0.11 12.9 0.0 0.25 11.8 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding FAD_oxidored PF12831.7 OAG39630.1 - 0.13 11.6 0.0 0.29 10.5 0.0 1.6 1 0 0 1 1 1 0 FAD dependent oxidoreductase ApbA PF02558.16 OAG39630.1 - 0.14 11.8 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pro_isomerase PF00160.21 OAG39631.1 - 3.5e-47 160.6 0.2 5.3e-47 160.0 0.2 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_2 PF07719.17 OAG39631.1 - 8.7e-08 31.7 10.7 8.8e-07 28.6 1.7 3.8 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 OAG39631.1 - 1.5e-07 30.9 10.3 1.1e-06 28.2 0.9 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 OAG39631.1 - 4.7e-06 26.2 7.6 0.00045 19.8 0.8 3.1 2 0 0 2 2 2 2 TPR repeat TPR_12 PF13424.6 OAG39631.1 - 1.1e-05 25.6 5.7 1.4e-05 25.3 1.0 2.7 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 OAG39631.1 - 1.9e-05 24.5 0.5 1.9e-05 24.5 0.5 3.9 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 OAG39631.1 - 0.00017 22.1 5.7 0.0015 19.2 4.6 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_15 PF13429.6 OAG39631.1 - 0.0063 15.8 8.1 0.045 13.0 2.1 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 OAG39631.1 - 0.0086 16.2 2.0 0.05 13.8 0.8 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 OAG39631.1 - 0.015 15.9 4.1 0.015 15.9 4.1 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 OAG39631.1 - 0.05 14.1 2.1 0.05 14.1 2.1 3.1 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 OAG39631.1 - 0.14 12.6 1.6 18 6.0 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 OAG39631.1 - 4.5 7.5 5.3 1.7 8.9 0.5 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat HHV-1_VABD PF16852.5 OAG39633.1 - 0.043 13.8 0.2 9.3 6.4 0.0 2.7 2 0 0 2 2 2 0 Herpes viral adaptor-to-host cellular mRNA binding domain Aldo_ket_red PF00248.21 OAG39635.1 - 9e-49 166.2 0.0 1.1e-48 166.0 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Plus-3 PF03126.18 OAG39637.1 - 8.9e-26 90.6 0.0 9.4e-25 87.3 0.0 2.3 2 0 0 2 2 2 1 Plus-3 domain Endotoxin_C2 PF18449.1 OAG39637.1 - 0.023 15.0 1.7 0.07 13.5 1.7 1.9 1 0 0 1 1 1 0 Delta endotoxin COQ7 PF03232.13 OAG39638.1 - 2.9e-70 235.5 0.1 3.5e-70 235.2 0.1 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.17 OAG39638.1 - 6.2e-06 26.7 0.0 2e-05 25.0 0.0 1.8 1 1 0 1 1 1 1 Rubrerythrin Crr6 PF08847.11 OAG39638.1 - 0.028 14.1 0.0 0.068 12.8 0.0 1.6 1 1 0 1 1 1 0 Chlororespiratory reduction 6 KAP_NTPase PF07693.14 OAG39638.1 - 0.15 11.3 0.0 0.21 10.8 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain Pkinase PF00069.25 OAG39640.1 - 2.7e-14 53.2 0.0 2.2e-10 40.4 0.0 3.0 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAG39640.1 - 2.1e-06 27.2 0.0 0.00013 21.3 0.0 3.0 1 1 0 1 1 1 1 Protein tyrosine kinase Ada3 PF10198.9 OAG39641.1 - 3.1e-46 156.8 0.0 3.1e-46 156.8 0.0 2.4 2 0 0 2 2 2 1 Histone acetyltransferases subunit 3 YqfQ PF14181.6 OAG39641.1 - 2.3 8.4 11.0 8.7 6.5 11.0 2.0 1 0 0 1 1 1 0 YqfQ-like protein zf-RING_2 PF13639.6 OAG39642.1 - 1.8e-12 47.3 5.5 3.1e-12 46.6 5.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 OAG39642.1 - 4.6e-09 35.8 3.0 8.4e-09 35.0 3.0 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 OAG39642.1 - 5.7e-09 35.7 4.7 9.8e-09 34.9 4.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAG39642.1 - 4.8e-07 29.6 3.7 8.2e-07 28.8 3.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OAG39642.1 - 3.6e-05 24.0 7.4 0.0002 21.6 7.5 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 OAG39642.1 - 3.8e-05 23.6 3.3 5.9e-05 22.9 3.3 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 OAG39642.1 - 4.2e-05 23.5 6.3 9.2e-05 22.4 6.3 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 OAG39642.1 - 0.00012 21.9 2.3 0.0002 21.1 2.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 OAG39642.1 - 0.0023 17.7 3.3 0.0055 16.5 3.3 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-ANAPC11 PF12861.7 OAG39642.1 - 0.0024 17.9 0.7 0.0051 16.8 0.7 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 OAG39642.1 - 0.011 15.5 10.6 0.43 10.5 10.5 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 OAG39642.1 - 0.022 14.9 6.1 0.043 14.0 6.1 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING TMEM154 PF15102.6 OAG39642.1 - 0.039 13.9 1.4 0.056 13.3 0.8 1.5 1 1 0 1 1 1 0 TMEM154 protein family zf-RING_4 PF14570.6 OAG39642.1 - 0.039 13.7 3.2 0.073 12.9 3.2 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PspB PF06667.12 OAG39642.1 - 0.11 12.5 0.7 0.23 11.6 0.7 1.5 1 0 0 1 1 1 0 Phage shock protein B zf-RING-like PF08746.11 OAG39642.1 - 0.18 12.1 2.5 0.38 11.1 2.5 1.6 1 1 0 1 1 1 0 RING-like domain Zn_ribbon_17 PF17120.5 OAG39642.1 - 0.18 11.4 1.4 0.38 10.4 1.4 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type LapA_dom PF06305.11 OAG39642.1 - 0.19 11.5 1.3 0.47 10.3 1.3 1.6 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Baculo_11_kDa PF06143.11 OAG39642.1 - 0.25 11.0 1.6 0.47 10.1 1.6 1.4 1 0 0 1 1 1 0 Baculovirus 11 kDa family FANCL_C PF11793.8 OAG39642.1 - 0.25 11.6 2.4 0.68 10.2 2.4 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain SIT PF15330.6 OAG39642.1 - 0.27 11.7 1.0 0.55 10.7 1.0 1.5 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT PHD PF00628.29 OAG39642.1 - 1.1 9.2 3.0 1.9 8.4 3.0 1.4 1 0 0 1 1 1 0 PHD-finger DUF4381 PF14316.6 OAG39642.1 - 1.5 9.0 4.9 1.8 8.8 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) zf-C3H2C3 PF17122.5 OAG39642.1 - 7 6.8 7.2 0.47 10.5 1.5 2.1 2 0 0 2 2 2 0 Zinc-finger FRG1 PF06229.12 OAG39643.1 - 2.9e-40 138.0 3.1 4.1e-40 137.6 3.1 1.2 1 0 0 1 1 1 1 FRG1-like domain APH PF01636.23 OAG39644.1 - 2.7e-08 34.0 0.1 3.5e-08 33.7 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 OAG39644.1 - 0.0019 17.8 0.0 0.0023 17.5 0.0 1.1 1 0 0 1 1 1 1 Choline/ethanolamine kinase Cupin_2 PF07883.11 OAG39645.1 - 1.4e-07 31.1 0.2 5.2e-06 26.1 0.2 2.4 1 1 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 OAG39645.1 - 1.3e-06 28.1 0.0 4.4e-06 26.4 0.0 1.7 2 0 0 2 2 2 1 Cupin Cupin_3 PF05899.12 OAG39645.1 - 0.014 15.1 0.1 0.079 12.7 0.1 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF861) Cupin_6 PF12852.7 OAG39645.1 - 0.02 14.6 0.5 0.14 11.8 0.4 2.0 1 1 0 1 1 1 0 Cupin MFS_1 PF07690.16 OAG39646.1 - 2.4e-16 59.6 53.7 4.5e-16 58.7 47.1 3.1 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 OAG39646.1 - 6.5e-07 28.1 11.1 6.5e-07 28.1 11.1 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Orf78 PF06024.12 OAG39646.1 - 0.045 14.1 0.0 0.19 12.0 0.0 2.1 1 0 0 1 1 1 0 Orf78 (ac78) GCP_C_terminal PF04130.13 OAG39647.1 - 1e-94 317.5 3.6 2.7e-94 316.1 3.6 1.8 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 OAG39647.1 - 8.1e-80 268.7 0.1 1.3e-78 264.8 0.0 2.3 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal p450 PF00067.22 OAG39648.1 - 2e-31 109.2 0.0 2.7e-31 108.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 ECM11 PF15463.6 OAG39648.1 - 0.17 12.5 0.1 0.45 11.1 0.1 1.7 1 0 0 1 1 1 0 Extracellular mutant protein 11 HET PF06985.11 OAG39649.1 - 2.9e-30 105.6 0.2 5.1e-30 104.7 0.2 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Gti1_Pac2 PF09729.9 OAG39650.1 - 3e-44 151.3 6.1 8.9e-38 130.2 0.1 2.8 2 1 1 3 3 3 2 Gti1/Pac2 family DUF2434 PF10361.9 OAG39651.1 - 5.2e-99 330.9 2.5 7.7e-99 330.4 2.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2434) tRNA-synt_2 PF00152.20 OAG39652.1 - 1.7e-62 211.3 0.0 3.6e-62 210.2 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 OAG39652.1 - 3.5e-10 39.7 0.0 6e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 OAG39652.1 - 0.0087 15.6 0.2 4 6.9 0.1 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) SAP30_Sin3_bdg PF13867.6 OAG39652.1 - 0.042 14.2 0.0 0.11 12.8 0.0 1.7 1 0 0 1 1 1 0 Sin3 binding region of histone deacetylase complex subunit SAP30 COesterase PF00135.28 OAG39653.1 - 6.7e-67 226.5 0.0 1e-66 225.9 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAG39653.1 - 3.3e-05 23.9 0.1 0.00045 20.1 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Toxin_29 PF08116.11 OAG39654.1 - 0.053 13.5 0.7 0.34 10.9 0.0 2.5 2 0 0 2 2 2 0 PhTx neurotoxin family NOA36 PF06524.12 OAG39655.1 - 0.88 8.8 3.3 1.3 8.3 3.3 1.1 1 0 0 1 1 1 0 NOA36 protein DUF4611 PF15387.6 OAG39655.1 - 3 8.1 5.3 6.3 7.1 5.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) NIF PF03031.18 OAG39656.1 - 2.3e-27 95.7 0.0 4.9e-27 94.6 0.0 1.5 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase BRCT PF00533.26 OAG39656.1 - 4.7e-10 39.7 0.0 1e-09 38.7 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 OAG39656.1 - 7.5e-10 38.6 0.5 1.6e-09 37.6 0.5 1.5 1 0 0 1 1 1 1 twin BRCT domain BRCT_2 PF16589.5 OAG39656.1 - 2.7e-05 24.5 0.1 0.00016 22.0 0.0 2.2 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 OAG39656.1 - 0.0027 18.0 1.0 0.0058 16.9 0.1 2.0 2 0 0 2 2 2 1 DNA ligase 3 BRCT domain BRCT_3 PF18428.1 OAG39656.1 - 0.054 13.6 0.1 0.13 12.4 0.1 1.6 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain Asp PF00026.23 OAG39657.1 - 8.1e-106 354.0 0.0 9.4e-106 353.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OAG39657.1 - 1.4e-14 54.8 1.6 2.1e-12 47.6 0.7 2.7 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 OAG39657.1 - 0.003 17.3 0.0 0.027 14.3 0.0 2.2 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 OAG39657.1 - 0.0051 17.4 0.2 5.1 7.8 0.1 3.3 2 2 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 OAG39657.1 - 0.011 16.3 0.0 8.2 7.1 0.0 3.3 2 2 0 2 2 2 0 gag-polyprotein putative aspartyl protease DUF2373 PF10180.9 OAG39658.1 - 6.6e-24 83.5 0.3 1.4e-23 82.4 0.3 1.6 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) Proteasome PF00227.26 OAG39659.1 - 2.5e-49 167.4 0.0 3.5e-49 166.9 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 OAG39659.1 - 5e-13 48.5 0.3 8.3e-13 47.8 0.3 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Amidase_5 PF05382.13 OAG39659.1 - 0.16 11.9 0.0 2.9 7.8 0.0 2.2 2 0 0 2 2 2 0 Bacteriophage peptidoglycan hydrolase TM231 PF10149.9 OAG39660.1 - 0.16 11.3 0.0 0.21 10.9 0.0 1.1 1 0 0 1 1 1 0 Transmembrane protein 231 adh_short PF00106.25 OAG39661.1 - 3e-35 121.4 0.0 3.1e-34 118.1 0.0 2.0 1 1 1 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG39661.1 - 7.2e-26 91.2 0.0 1.6e-25 90.0 0.0 1.5 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 OAG39661.1 - 3.9e-11 42.9 0.0 4.9e-10 39.3 0.0 2.0 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) KR PF08659.10 OAG39661.1 - 9.7e-07 28.9 0.0 2e-06 27.9 0.0 1.5 2 0 0 2 2 2 1 KR domain NmrA PF05368.13 OAG39661.1 - 0.052 13.1 0.0 0.075 12.6 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family Epimerase PF01370.21 OAG39661.1 - 0.098 12.1 0.0 0.57 9.6 0.0 2.2 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.26 OAG39661.1 - 0.13 12.2 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase FMO-like PF00743.19 OAG39662.1 - 4e-15 55.2 0.5 1.7e-14 53.1 0.0 2.1 3 0 0 3 3 3 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OAG39662.1 - 2.1e-09 37.1 0.0 7.7e-08 31.9 0.0 2.7 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAG39662.1 - 4.2e-08 32.8 0.0 0.00016 21.0 0.0 3.1 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG39662.1 - 1.1e-07 32.0 0.0 4.1e-07 30.1 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 OAG39662.1 - 3.2e-06 26.5 0.2 7.9e-05 22.0 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 OAG39662.1 - 0.075 13.6 0.0 2.3 8.8 0.0 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase RPAP1_C PF08620.10 OAG39663.1 - 1.6e-26 92.2 0.0 4.7e-26 90.7 0.0 1.8 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.10 OAG39663.1 - 1.7e-15 56.5 6.5 4e-15 55.3 6.5 1.7 1 0 0 1 1 1 1 RPAP1-like, N-terminal Fn_bind PF02986.14 OAG39663.1 - 1.5 8.7 4.1 0.7 9.7 0.5 2.4 2 0 0 2 2 2 0 Fibronectin binding repeat HUN PF08729.10 OAG39664.1 - 9.8e-08 31.9 0.0 1.9e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 HPC2 and ubinuclein domain PAS_9 PF13426.7 OAG39665.1 - 9.2e-25 86.9 0.0 1.1e-15 57.8 0.0 3.8 4 0 0 4 4 4 3 PAS domain PAS_3 PF08447.12 OAG39665.1 - 6.3e-19 68.1 0.0 2.6e-10 40.5 0.0 4.1 4 0 0 4 4 4 3 PAS fold GATA PF00320.27 OAG39665.1 - 1.9e-14 53.0 7.9 3.8e-14 52.0 7.9 1.6 1 0 0 1 1 1 1 GATA zinc finger PAS PF00989.25 OAG39665.1 - 1.4e-10 41.2 0.0 0.051 13.6 0.0 3.5 3 0 0 3 3 3 3 PAS fold PAS_11 PF14598.6 OAG39665.1 - 3.3e-08 33.6 0.0 0.012 15.8 0.0 2.8 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.10 OAG39665.1 - 4e-07 30.3 0.0 0.019 15.2 0.0 3.6 3 0 0 3 3 3 2 PAS fold Cytochrom_C_2 PF01322.20 OAG39665.1 - 0.16 12.9 0.7 0.41 11.5 0.1 1.9 2 0 0 2 2 2 0 Cytochrome C' DUF3176 PF11374.8 OAG39666.1 - 6e-30 103.6 0.2 1.7e-29 102.2 0.2 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) DUF1129 PF06570.11 OAG39666.1 - 0.055 12.9 0.2 0.15 11.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) Ras PF00071.22 OAG39667.1 - 1.9e-38 131.6 0.0 1.8e-24 86.2 0.0 2.0 2 0 0 2 2 2 2 Ras family Roc PF08477.13 OAG39667.1 - 4.6e-12 46.2 0.0 9.9e-12 45.1 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAG39667.1 - 0.00063 19.2 0.1 0.0027 17.2 0.1 1.9 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OAG39667.1 - 0.0042 17.1 0.0 0.0065 16.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OAG39667.1 - 0.023 14.2 0.0 0.39 10.2 0.0 2.6 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain PRK PF00485.18 OAG39667.1 - 0.087 12.6 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family PLDc PF00614.22 OAG39668.1 - 1.4e-17 63.0 0.4 1.6e-08 34.4 0.3 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 OAG39668.1 - 1.6e-13 50.7 0.1 5.7e-07 29.5 0.0 3.2 3 1 0 3 3 3 2 PLD-like domain PX PF00787.24 OAG39668.1 - 1.7e-11 44.1 0.1 5e-11 42.6 0.1 1.8 1 0 0 1 1 1 1 PX domain PGA2 PF07543.12 OAG39668.1 - 1.3 9.0 5.3 2.7 8.0 2.0 3.0 2 0 0 2 2 2 0 Protein trafficking PGA2 IRF PF00605.17 OAG39669.1 - 0.16 12.3 0.2 0.32 11.3 0.2 1.4 1 0 0 1 1 1 0 Interferon regulatory factor transcription factor MFS_1 PF07690.16 OAG39670.1 - 7.3e-34 117.2 19.9 7.3e-34 117.2 19.9 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1772 PF08592.11 OAG39670.1 - 1.5 9.2 5.5 29 5.0 1.8 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1772) Acetyltransf_13 PF13880.6 OAG39671.1 - 1.3e-29 101.9 0.0 2.4e-29 101.1 0.0 1.5 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.6 OAG39671.1 - 8.7e-14 51.1 0.2 1.6e-13 50.2 0.2 1.5 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Fungal_trans PF04082.18 OAG39672.1 - 0.0001 21.5 1.4 0.00015 20.9 1.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG39672.1 - 0.003 17.7 1.4 0.0055 16.8 1.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain COesterase PF00135.28 OAG39673.1 - 1.1e-38 133.4 0.0 4.3e-29 101.8 0.0 3.0 2 1 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 OAG39673.1 - 0.015 15.1 0.1 0.052 13.4 0.0 1.8 2 0 0 2 2 2 0 alpha/beta hydrolase fold 2-oxoacid_dh PF00198.23 OAG39674.1 - 1e-79 267.3 0.3 1.5e-79 266.7 0.3 1.3 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 OAG39674.1 - 1.4e-18 66.5 1.8 2.5e-18 65.7 1.8 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 OAG39674.1 - 0.00041 20.1 0.1 0.0024 17.7 0.0 2.1 1 1 1 2 2 2 1 Biotin-lipoyl like HlyD_3 PF13437.6 OAG39674.1 - 0.001 19.8 0.2 0.041 14.6 0.0 2.4 1 1 1 2 2 2 1 HlyD family secretion protein RnfC_N PF13375.6 OAG39674.1 - 0.0012 18.7 0.5 1.7 8.7 0.0 2.7 1 1 1 2 2 2 2 RnfC Barrel sandwich hybrid domain HlyD_D23 PF16576.5 OAG39674.1 - 0.034 13.4 0.1 0.13 11.5 0.1 1.7 1 1 0 1 1 1 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion GCV_H PF01597.19 OAG39674.1 - 0.1 12.5 0.5 0.27 11.1 0.4 1.8 1 1 0 1 1 1 0 Glycine cleavage H-protein DUF3391 PF11871.8 OAG39674.1 - 0.56 10.7 6.1 1.3 9.5 6.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) Mitofilin PF09731.9 OAG39674.1 - 9.3 5.0 8.9 12 4.6 8.9 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Ndc1_Nup PF09531.10 OAG39674.1 - 10 4.7 5.9 14 4.2 5.9 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Complex1_LYR PF05347.15 OAG39675.1 - 7.6e-09 35.5 2.1 1.2e-08 34.8 2.1 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Histone_H2A_C PF16211.5 OAG39676.1 - 2e-21 75.4 2.6 3.7e-21 74.5 2.6 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 OAG39676.1 - 1.3e-16 61.2 0.0 1.7e-16 60.7 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 OAG39676.1 - 9.8e-06 25.8 0.0 1.3e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 OAG39677.1 - 3.8e-21 75.8 0.3 4.7e-21 75.5 0.3 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 OAG39677.1 - 4.8e-05 23.6 0.0 0.00011 22.4 0.0 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 OAG39677.1 - 0.00028 21.3 0.0 0.00046 20.6 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A DUF1018 PF06252.12 OAG39677.1 - 0.055 14.5 0.4 0.075 14.0 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) RP-C PF03428.13 OAG39677.1 - 0.073 12.7 0.1 0.17 11.6 0.1 1.6 1 1 0 1 1 1 0 Replication protein C N-terminal domain Peptidase_C54 PF03416.19 OAG39678.1 - 2.2e-97 325.8 0.0 2.7e-97 325.5 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 G-patch PF01585.23 OAG39679.1 - 2.4e-09 36.9 1.5 2.4e-09 36.9 1.5 2.2 2 0 0 2 2 2 1 G-patch domain R3H PF01424.22 OAG39679.1 - 2.3e-08 33.9 0.0 5.4e-08 32.7 0.0 1.7 1 0 0 1 1 1 1 R3H domain G-patch_2 PF12656.7 OAG39679.1 - 0.0025 17.9 1.3 0.0098 16.0 1.3 2.1 1 0 0 1 1 1 1 G-patch domain FAD_binding_3 PF01494.19 OAG39680.1 - 5.6e-17 62.0 0.0 8.5e-17 61.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 OAG39680.1 - 8e-06 25.3 0.4 0.024 13.9 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 OAG39680.1 - 4.8e-05 22.4 1.0 0.019 13.8 0.1 2.5 3 0 0 3 3 3 2 Tryptophan halogenase DAO PF01266.24 OAG39680.1 - 6.4e-05 22.7 0.9 0.00034 20.3 0.2 2.1 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 OAG39680.1 - 0.0022 18.0 0.4 0.15 12.1 0.1 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 OAG39680.1 - 0.0034 17.9 0.2 2.9 8.5 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG39680.1 - 0.0046 17.2 0.1 0.013 15.8 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 OAG39680.1 - 0.093 11.8 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 OAG39680.1 - 0.13 11.2 0.3 2.5 7.1 0.2 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 OAG39680.1 - 0.14 11.4 0.0 13 5.0 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAG39680.1 - 0.23 10.7 0.2 0.35 10.1 0.2 1.2 1 0 0 1 1 1 0 Thi4 family CBM_1 PF00734.18 OAG39681.1 - 6.7e-14 51.6 13.5 2.2e-13 49.9 13.5 2.0 1 0 0 1 1 1 1 Fungal cellulose binding domain DPBB_1 PF03330.18 OAG39681.1 - 0.0011 19.2 0.0 0.003 17.8 0.0 1.8 1 1 0 1 1 1 1 Lytic transglycolase HD PF01966.22 OAG39682.1 - 1.4e-06 28.5 0.0 2.2e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 HD domain Methyltransf_23 PF13489.6 OAG39683.1 - 8.5e-06 25.7 0.0 1.5e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG39683.1 - 0.01 16.6 0.0 0.058 14.1 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain CheR PF01739.18 OAG39683.1 - 0.25 10.8 0.0 0.46 9.9 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain MFS_1 PF07690.16 OAG39684.1 - 3.5e-33 115.0 30.5 3.5e-33 115.0 30.5 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Acetyltransf_7 PF13508.7 OAG39685.1 - 5.9e-08 33.0 0.0 1.1e-07 32.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OAG39685.1 - 6.1e-07 29.4 0.0 1e-06 28.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAG39685.1 - 1.4e-06 28.5 0.1 3.1e-06 27.4 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 OAG39685.1 - 0.0013 18.8 0.0 0.0035 17.4 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain AA_permease_2 PF13520.6 OAG39687.1 - 5e-51 173.9 54.8 5.7e-51 173.7 54.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAG39687.1 - 3.2e-27 95.3 43.4 4e-27 94.9 43.4 1.0 1 0 0 1 1 1 1 Amino acid permease Aldedh PF00171.22 OAG39688.1 - 1.8e-145 485.0 0.0 2.2e-145 484.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Fungal_trans PF04082.18 OAG39689.1 - 2.1e-61 207.3 0.1 3.2e-61 206.7 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 OAG39689.1 - 0.00035 20.9 10.2 0.0094 16.4 1.2 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type DUF5570 PF17731.1 OAG39689.1 - 0.01 15.9 0.0 0.023 14.8 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5570) zf-H2C2_2 PF13465.6 OAG39689.1 - 0.19 12.2 5.9 0.29 11.6 1.7 3.0 3 0 0 3 3 3 0 Zinc-finger double domain MR_MLE_C PF13378.6 OAG39690.1 - 8e-55 185.8 0.1 1e-54 185.4 0.1 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 OAG39690.1 - 2.8e-20 72.7 0.0 5.1e-20 71.8 0.0 1.4 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain SET PF00856.28 OAG39691.1 - 6.1e-11 43.0 0.0 6.2e-10 39.7 0.0 2.4 1 1 0 1 1 1 1 SET domain Helo_like_N PF17111.5 OAG39692.1 - 3.9e-10 39.5 0.7 6.9e-10 38.7 0.7 1.4 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins adh_short_C2 PF13561.6 OAG39693.1 - 2.1e-52 178.0 1.3 4.4e-47 160.6 0.0 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG39693.1 - 1e-46 158.9 0.9 4.5e-38 130.7 0.0 2.1 1 1 1 2 2 2 2 short chain dehydrogenase KR PF08659.10 OAG39693.1 - 1.2e-08 35.1 1.3 3e-08 33.8 1.3 1.7 1 1 0 1 1 1 1 KR domain Glyco_transf_5 PF08323.11 OAG39693.1 - 0.00041 20.1 0.0 0.041 13.6 0.0 2.5 3 0 0 3 3 3 1 Starch synthase catalytic domain Epimerase PF01370.21 OAG39693.1 - 0.053 13.0 0.1 0.1 12.1 0.1 1.6 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Glyco_transf_4 PF13439.6 OAG39693.1 - 0.072 13.1 0.1 2.4 8.1 0.0 2.7 3 0 0 3 3 3 0 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 OAG39693.1 - 0.23 11.9 3.6 23 5.4 0.6 3.0 2 1 0 3 3 3 0 Glycosyl transferase 4-like domain DDE_1 PF03184.19 OAG39694.1 - 0.01 15.5 0.0 0.018 14.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 OAG39694.1 - 0.034 14.2 0.0 0.065 13.3 0.0 1.5 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain Ank_2 PF12796.7 OAG39695.1 - 1.8e-45 153.4 0.7 5.5e-13 49.3 0.0 4.7 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAG39695.1 - 2.3e-33 114.2 0.0 1.1e-07 32.3 0.0 7.2 1 1 6 7 7 7 6 Ankyrin repeats (many copies) Ank PF00023.30 OAG39695.1 - 1.5e-22 79.0 2.1 0.039 14.4 0.0 7.8 7 0 0 7 7 7 6 Ankyrin repeat Ank_3 PF13606.6 OAG39695.1 - 5.9e-20 69.2 0.0 0.48 11.1 0.0 7.6 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 OAG39695.1 - 1.9e-15 56.7 0.4 0.0028 17.9 0.0 6.6 2 1 5 7 7 7 6 Ankyrin repeats (many copies) NACHT PF05729.12 OAG39695.1 - 7.7e-09 35.7 0.1 1.7e-08 34.6 0.1 1.6 1 0 0 1 1 1 1 NACHT domain Helo_like_N PF17111.5 OAG39695.1 - 9.9e-09 34.9 0.1 2.1e-08 33.8 0.1 1.5 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins AAA_16 PF13191.6 OAG39695.1 - 1.1e-06 29.1 0.2 3.3e-06 27.6 0.2 1.8 1 0 0 1 1 1 1 AAA ATPase domain Baculo_PEP_C PF04513.12 OAG39695.1 - 0.00052 20.1 0.7 1.8 8.6 0.0 3.0 3 0 0 3 3 3 2 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_22 PF13401.6 OAG39695.1 - 0.0062 16.8 0.3 0.037 14.3 0.0 2.4 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.6 OAG39695.1 - 0.0069 16.4 0.0 0.5 10.4 0.0 2.9 2 1 0 2 2 2 1 AAA domain SesA PF17107.5 OAG39695.1 - 0.024 14.8 0.1 0.071 13.3 0.1 1.8 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases PIN_8 PF18476.1 OAG39695.1 - 0.031 14.1 1.1 0.12 12.2 1.3 1.9 2 0 0 2 2 2 0 PIN like domain RTC4 PF14474.6 OAG39695.1 - 0.052 13.7 1.8 3.7 7.7 0.1 2.8 2 0 0 2 2 2 0 RTC4-like domain ATPase_2 PF01637.18 OAG39695.1 - 0.064 13.2 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Nse4-Nse3_bdg PF15412.6 OAG39695.1 - 0.11 12.6 2.9 2.6 8.2 0.0 4.0 5 0 0 5 5 4 0 Binding domain of Nse4/EID3 to Nse3-MAGE NB-ARC PF00931.22 OAG39695.1 - 0.11 11.6 0.0 0.37 9.9 0.0 1.8 1 0 0 1 1 1 0 NB-ARC domain NPV_P10 PF05531.12 OAG39695.1 - 0.47 10.9 3.5 7.4 7.1 0.1 3.2 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein YajC PF02699.15 OAG39695.1 - 1.4 8.9 7.5 4.1 7.3 0.4 3.9 3 1 1 4 4 4 0 Preprotein translocase subunit Methyltransf_23 PF13489.6 OAG39697.1 - 1.8e-22 79.9 0.0 2.6e-22 79.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG39697.1 - 2.8e-10 40.8 0.0 6e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG39697.1 - 1.3e-07 31.5 0.0 2.7e-06 27.3 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG39697.1 - 1.5e-07 31.9 0.0 3e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG39697.1 - 2.3e-05 25.1 0.0 7.7e-05 23.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 OAG39697.1 - 0.013 14.9 0.0 0.018 14.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 OAG39697.1 - 0.02 14.5 0.0 0.05 13.1 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_16 PF10294.9 OAG39697.1 - 0.061 13.0 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase DUF938 PF06080.12 OAG39697.1 - 0.16 11.7 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) p450 PF00067.22 OAG39698.1 - 8.2e-62 209.4 0.0 9.9e-62 209.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PLDc_2 PF13091.6 OAG39699.1 - 2.2e-19 69.7 0.0 3.5e-13 49.6 0.0 3.6 2 2 0 2 2 2 2 PLD-like domain PLDc PF00614.22 OAG39699.1 - 1.2e-05 25.3 0.1 0.015 15.5 0.0 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif Regulator_TrmB PF11495.8 OAG39699.1 - 0.07 12.3 0.3 6.8 5.8 0.0 3.2 4 0 0 4 4 4 0 Archaeal transcriptional regulator TrmB FAM83 PF07894.12 OAG39699.1 - 0.073 12.6 0.3 30 4.1 0.0 3.0 3 0 0 3 3 3 0 FAM83 A-H GH3 PF03321.13 OAG39699.1 - 0.097 11.5 0.1 0.14 11.0 0.1 1.1 1 0 0 1 1 1 0 GH3 auxin-responsive promoter CT_A_B PF02626.15 OAG39700.1 - 2.5e-76 256.8 0.0 5e-76 255.8 0.0 1.5 2 0 0 2 2 2 1 Carboxyltransferase domain, subdomain A and B CPSase_L_D2 PF02786.17 OAG39700.1 - 5.4e-58 196.0 0.0 9.2e-58 195.2 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 OAG39700.1 - 2.2e-38 131.2 0.0 7.3e-38 129.5 0.0 1.9 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 OAG39700.1 - 1.4e-34 118.4 0.0 6.3e-34 116.3 0.0 2.0 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain CT_C_D PF02682.16 OAG39700.1 - 2.4e-22 79.7 0.0 4.7e-22 78.7 0.0 1.4 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain C and D Biotin_lipoyl PF00364.22 OAG39700.1 - 2.7e-11 43.1 2.3 5.7e-11 42.1 1.5 2.0 2 0 0 2 2 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 OAG39700.1 - 5.6e-07 29.3 0.0 1.3e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.6 OAG39700.1 - 6.9e-05 22.6 0.5 0.36 10.7 0.1 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp PF02222.22 OAG39700.1 - 0.0037 16.8 0.0 0.0075 15.8 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 OAG39700.1 - 0.0038 16.8 0.0 0.016 14.8 0.0 2.0 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_5 PF13549.6 OAG39700.1 - 0.045 13.2 0.2 0.12 11.8 0.0 1.8 2 0 0 2 2 2 0 ATP-grasp domain Glyco_hydro_4C PF11975.8 OAG39700.1 - 0.17 11.9 0.6 28 4.7 0.7 2.3 2 0 0 2 2 2 0 Family 4 glycosyl hydrolase C-terminal domain APG6_N PF17675.1 OAG39700.1 - 1.4 9.4 8.4 4.1 7.9 8.4 1.7 1 0 0 1 1 1 0 Apg6 coiled-coil region LamB_YcsF PF03746.16 OAG39701.1 - 2.7e-83 279.3 0.0 3e-83 279.2 0.0 1.0 1 0 0 1 1 1 1 LamB/YcsF family Homeobox_KN PF05920.11 OAG39702.1 - 1.2e-16 60.4 0.8 3.6e-16 58.8 0.5 2.1 2 0 0 2 2 2 1 Homeobox KN domain HTH_Tnp_Tc5 PF03221.16 OAG39702.1 - 0.0001 22.3 0.3 0.00028 20.9 0.3 1.8 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Homeodomain PF00046.29 OAG39702.1 - 0.00033 20.4 0.2 0.00033 20.4 0.2 2.0 2 0 0 2 2 2 1 Homeodomain zf-C2H2_4 PF13894.6 OAG39702.1 - 0.007 17.1 1.1 0.007 17.1 1.1 4.8 5 0 0 5 5 5 2 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 OAG39702.1 - 0.046 14.4 7.8 1.6 9.4 0.2 2.3 2 0 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-C2H2 PF00096.26 OAG39702.1 - 0.1 13.1 19.1 0.18 12.3 0.9 4.4 4 0 0 4 4 4 0 Zinc finger, C2H2 type Init_tRNA_PT PF04179.12 OAG39702.1 - 0.14 12.5 0.0 0.29 11.5 0.0 1.5 1 0 0 1 1 1 0 Rit1 DUSP-like domain Elf1 PF05129.13 OAG39702.1 - 3.1 7.9 6.2 8.2 6.5 3.4 2.6 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like zf-C2H2_2 PF12756.7 OAG39702.1 - 4.4 7.7 7.7 1e+02 3.3 0.3 3.2 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) C5HCH PF17982.1 OAG39702.1 - 4.5 7.5 7.8 4.8 7.4 0.1 3.2 3 0 0 3 3 3 0 NSD Cys-His rich domain DUF2207 PF09972.9 OAG39703.1 - 0.14 10.8 0.0 0.2 10.3 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) UQ_con PF00179.26 OAG39704.1 - 9.1e-11 41.6 0.0 1.6e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 OAG39704.1 - 0.03 14.6 0.0 0.067 13.5 0.0 1.5 1 0 0 1 1 1 0 RWD domain Phage_Coat_B PF05356.11 OAG39705.1 - 0.18 11.7 0.9 0.74 9.8 0.2 2.3 2 0 0 2 2 2 0 Phage Coat protein B 2OG-FeII_Oxy_2 PF13532.6 OAG39706.1 - 9.9e-35 120.5 0.0 1.4e-34 120.0 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-GRF PF06839.12 OAG39706.1 - 3.2e-09 36.7 8.0 6.8e-09 35.7 8.0 1.5 1 0 0 1 1 1 1 GRF zinc finger TPK_catalytic PF04263.16 OAG39706.1 - 0.12 12.4 0.0 1.2 9.2 0.0 2.1 2 0 0 2 2 2 0 Thiamin pyrophosphokinase, catalytic domain DMA PF03474.14 OAG39706.1 - 0.12 12.0 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 DMRTA motif WD40 PF00400.32 OAG39707.1 - 6.6e-17 61.6 16.8 0.0032 18.3 0.1 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.8 OAG39707.1 - 0.0021 16.8 0.4 0.21 10.2 0.1 2.3 1 1 0 2 2 2 2 Nucleoporin Nup120/160 PQQ_3 PF13570.6 OAG39707.1 - 0.063 13.8 0.4 4 8.1 0.1 3.3 3 0 0 3 3 3 0 PQQ-like domain eIF2A PF08662.11 OAG39707.1 - 0.068 13.0 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A Ribonuclease PF00545.20 OAG39708.1 - 5.6e-06 27.0 0.0 8.2e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 ribonuclease Ccdc124 PF06244.12 OAG39709.1 - 1.2e-28 100.2 25.2 7.3e-27 94.5 25.2 2.3 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 SWI-SNF_Ssr4 PF08549.10 OAG39709.1 - 3.6 6.1 16.3 4.8 5.7 16.3 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Ndc1_Nup PF09531.10 OAG39709.1 - 7.3 5.2 5.9 7.1 5.2 5.9 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TFIID-18kDa PF02269.16 OAG39710.1 - 1.3e-23 82.8 2.7 4.3e-13 49.1 0.3 3.2 2 1 1 3 3 3 2 Transcription initiation factor IID, 18kD subunit ALMS_repeat PF18727.1 OAG39710.1 - 0.14 12.0 0.1 0.32 10.9 0.1 1.5 1 0 0 1 1 1 0 Alstrom syndrome repeat Cadherin_C PF01049.17 OAG39710.1 - 0.18 12.1 4.0 0.39 11.1 0.8 2.4 2 0 0 2 2 2 0 Cadherin cytoplasmic region TP_methylase PF00590.20 OAG39711.1 - 2.9e-22 79.6 0.1 7.4e-22 78.3 0.1 1.6 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Radial_spoke PF04712.12 OAG39712.1 - 0.022 13.7 0.3 0.035 13.1 0.3 1.3 1 0 0 1 1 1 0 Radial spokehead-like protein CDC45 PF02724.14 OAG39712.1 - 0.21 9.9 0.5 0.28 9.5 0.5 1.3 1 0 0 1 1 1 0 CDC45-like protein RRM_1 PF00076.22 OAG39713.1 - 4.4e-27 93.7 0.0 1.2e-13 50.6 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OAG39713.1 - 0.00055 19.7 0.0 0.062 13.2 0.0 2.1 2 0 0 2 2 2 2 Occluded RNA-recognition motif RRM_3 PF08777.11 OAG39713.1 - 0.036 14.1 0.0 0.25 11.4 0.0 1.9 2 0 0 2 2 2 0 RNA binding motif CSD PF00313.22 OAG39713.1 - 0.13 12.1 0.2 0.39 10.6 0.0 1.8 2 0 0 2 2 2 0 'Cold-shock' DNA-binding domain Cupin_8 PF13621.6 OAG39714.1 - 4.6e-38 131.4 0.0 6.7e-38 130.8 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 OAG39714.1 - 3.4e-06 26.8 0.0 0.0021 17.6 0.0 2.2 2 0 0 2 2 2 2 Cupin superfamily protein JmjC PF02373.22 OAG39714.1 - 0.00028 21.3 0.0 0.00058 20.3 0.0 1.5 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 OAG39714.1 - 0.088 12.5 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 Cupin domain AA_permease_2 PF13520.6 OAG39715.1 - 2e-63 214.7 51.7 2.5e-63 214.4 51.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAG39715.1 - 3.6e-18 65.4 42.0 4.8e-18 65.0 42.0 1.1 1 0 0 1 1 1 1 Amino acid permease FAD_binding_4 PF01565.23 OAG39716.1 - 1e-26 93.3 8.7 2e-26 92.4 8.7 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 OAG39716.1 - 2.2e-09 37.3 2.3 6.6e-09 35.7 2.3 1.8 1 0 0 1 1 1 1 Berberine and berberine like AroM PF07302.11 OAG39716.1 - 0.15 11.4 0.4 0.44 9.9 0.2 1.7 2 0 0 2 2 2 0 AroM protein ABC_membrane PF00664.23 OAG39717.1 - 1.8e-79 267.3 32.2 1e-42 146.7 9.2 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 OAG39717.1 - 3e-61 205.9 0.0 4e-30 105.1 0.0 3.2 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 OAG39717.1 - 2.6e-17 63.0 0.8 3e-07 30.1 0.3 3.4 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 OAG39717.1 - 5.3e-08 33.4 1.1 0.024 15.0 0.0 3.6 3 1 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 OAG39717.1 - 6.5e-08 32.9 1.3 0.0066 16.7 0.0 3.8 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.6 OAG39717.1 - 1.3e-07 31.3 0.6 0.0005 19.8 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_ATPase PF09818.9 OAG39717.1 - 1.5e-07 30.6 0.3 0.079 11.7 0.0 3.2 3 0 0 3 3 3 2 Predicted ATPase of the ABC class RsgA_GTPase PF03193.16 OAG39717.1 - 4.3e-07 30.0 0.0 0.016 15.1 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_30 PF13604.6 OAG39717.1 - 3.7e-05 23.5 0.4 0.35 10.6 0.0 3.7 4 0 0 4 4 4 2 AAA domain AAA_15 PF13175.6 OAG39717.1 - 6.8e-05 22.7 0.0 0.31 10.7 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 OAG39717.1 - 0.00013 21.9 0.0 0.47 10.2 0.0 3.2 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system Rad17 PF03215.15 OAG39717.1 - 0.00021 21.3 0.0 0.64 9.9 0.0 2.4 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_23 PF13476.6 OAG39717.1 - 0.00028 21.5 0.1 0.0098 16.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 OAG39717.1 - 0.00062 19.4 0.0 1.4 8.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 OAG39717.1 - 0.0011 19.5 0.6 38 4.7 0.0 4.3 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 OAG39717.1 - 0.0019 18.2 0.0 5 7.1 0.0 3.3 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 OAG39717.1 - 0.0024 17.4 0.0 2.7 7.4 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_14 PF13173.6 OAG39717.1 - 0.0033 17.5 0.0 1.3 9.1 0.0 3.3 4 0 0 4 4 3 1 AAA domain PRK PF00485.18 OAG39717.1 - 0.0044 16.8 0.0 2.1 8.1 0.0 2.3 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family SbcCD_C PF13558.6 OAG39717.1 - 0.0092 16.2 1.5 2.8 8.2 0.2 3.7 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit ATP-synt_ab PF00006.25 OAG39717.1 - 0.01 15.5 0.0 0.92 9.1 0.0 2.6 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_18 PF13238.6 OAG39717.1 - 0.026 15.1 0.0 5.8 7.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 OAG39717.1 - 0.03 13.9 0.0 8.6 5.9 0.0 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Zeta_toxin PF06414.12 OAG39717.1 - 0.033 13.5 0.3 2.9 7.1 0.0 2.9 3 0 0 3 3 3 0 Zeta toxin AAA_33 PF13671.6 OAG39717.1 - 0.038 14.1 0.0 1.9 8.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 OAG39717.1 - 0.1 12.8 0.0 13 6.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 OAG39717.1 - 0.11 12.2 0.4 18 5.0 0.2 2.4 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 OAG39717.1 - 0.16 12.0 0.2 1.5 8.9 0.1 2.2 2 0 0 2 2 2 0 Helicase HerA, central domain MMR_HSR1 PF01926.23 OAG39717.1 - 0.17 12.0 0.0 17 5.5 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase RNA_helicase PF00910.22 OAG39717.1 - 0.2 12.1 0.0 32 5.0 0.0 2.6 2 0 0 2 2 2 0 RNA helicase Fungal_trans PF04082.18 OAG39718.1 - 0.0053 15.8 0.0 0.0083 15.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain ADH_zinc_N PF00107.26 OAG39719.1 - 3.3e-11 43.3 0.0 6e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAG39719.1 - 3.6e-10 41.0 0.0 7.7e-10 39.9 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG39719.1 - 6.9e-06 25.9 0.4 0.00015 21.6 0.2 2.5 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.6 OAG39719.1 - 0.0041 17.0 0.5 0.007 16.3 0.5 1.3 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 OAG39719.1 - 0.0043 16.5 0.2 0.0072 15.8 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase ADH_N_2 PF16884.5 OAG39719.1 - 0.0093 15.9 0.0 0.023 14.6 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase Epimerase PF01370.21 OAG39719.1 - 0.043 13.3 0.0 0.059 12.8 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 OAG39719.1 - 0.12 11.5 0.1 0.17 11.0 0.1 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Pro-kuma_activ PF09286.11 OAG39720.1 - 4.6e-31 108.0 0.0 8.7e-31 107.1 0.0 1.5 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 OAG39720.1 - 1.8e-05 24.2 0.0 3e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Subtilase family SecIII_SopE_N PF05364.14 OAG39720.1 - 0.016 15.3 0.1 0.057 13.5 0.1 1.9 1 0 0 1 1 1 0 Salmonella type III secretion SopE effector N-terminus Kinesin PF00225.23 OAG39721.1 - 3.7e-107 358.1 0.2 3.7e-107 358.1 0.2 1.9 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 OAG39721.1 - 1.8e-27 96.1 0.1 6.1e-27 94.4 0.1 1.9 1 0 0 1 1 1 1 Microtubule binding DUF3682 PF12446.8 OAG39721.1 - 0.54 10.7 3.2 1.9 9.0 3.2 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) Abhydrolase_6 PF12697.7 OAG39722.1 - 4.7e-10 40.5 1.7 5.6e-10 40.2 1.7 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAG39722.1 - 4.6e-09 36.3 0.0 8.1e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold His_Phos_1 PF00300.22 OAG39723.1 - 0.0032 17.2 0.9 4.3 7.0 0.0 3.6 3 1 0 3 3 3 3 Histidine phosphatase superfamily (branch 1) Thiolase_N PF00108.23 OAG39724.1 - 2.4e-90 302.4 2.0 4.2e-90 301.6 2.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 OAG39724.1 - 7e-39 132.3 0.6 2.1e-38 130.8 0.6 1.8 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 OAG39724.1 - 0.00018 21.2 2.9 0.0015 18.2 2.9 2.3 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 OAG39724.1 - 0.038 13.8 2.8 7.2 6.5 0.0 3.1 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III UQ_con PF00179.26 OAG39725.1 - 2e-51 173.3 0.0 2.3e-51 173.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OAG39725.1 - 0.00088 19.0 0.0 0.00098 18.8 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 OAG39725.1 - 0.061 13.6 0.0 0.099 12.9 0.0 1.5 1 1 0 1 1 1 0 RWD domain Peptidase_C1_2 PF03051.15 OAG39726.1 - 5.1e-158 526.4 0.0 6.2e-158 526.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.23 OAG39726.1 - 4.2e-09 36.8 0.1 0.00043 20.5 0.0 2.6 2 1 0 2 2 2 2 Papain family cysteine protease DUF4296 PF14129.6 OAG39726.1 - 0.093 13.3 0.0 0.24 12.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4296) MLANA PF14991.6 OAG39728.1 - 0.026 14.8 0.1 0.057 13.7 0.1 1.5 1 0 0 1 1 1 0 Protein melan-A Kringle PF00051.18 OAG39728.1 - 0.12 12.7 0.9 0.27 11.6 0.9 1.6 1 0 0 1 1 1 0 Kringle domain TFR_dimer PF04253.15 OAG39729.1 - 9.4e-27 93.5 0.0 9.3e-26 90.3 0.0 2.1 2 0 0 2 2 2 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 OAG39729.1 - 1.4e-24 86.8 0.0 2.4e-24 86.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 OAG39729.1 - 2.3e-09 37.1 0.2 8.3e-09 35.4 0.2 1.9 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 OAG39729.1 - 0.0033 17.1 0.0 0.0058 16.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Nicastrin PF05450.15 OAG39729.1 - 0.047 13.1 0.0 0.094 12.2 0.0 1.4 1 0 0 1 1 1 0 Nicastrin Fungal_trans_2 PF11951.8 OAG39730.1 - 0.0022 16.9 0.4 0.0081 15.0 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain FAD_binding_3 PF01494.19 OAG39732.1 - 1e-24 87.5 0.0 1.6e-24 86.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAG39732.1 - 2.1e-09 37.4 1.2 1.3e-06 28.3 1.0 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG39732.1 - 8.7e-08 31.7 0.0 0.0073 15.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OAG39732.1 - 3.2e-06 26.5 0.3 2e-05 23.8 0.4 2.0 1 1 0 1 1 1 1 Lycopene cyclase protein Amino_oxidase PF01593.24 OAG39732.1 - 3.8e-06 26.5 0.2 0.0061 15.9 0.0 2.7 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OAG39732.1 - 4.5e-06 26.8 0.2 1.1e-05 25.6 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 OAG39732.1 - 2.7e-05 23.4 0.1 4.3e-05 22.8 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 OAG39732.1 - 0.00021 20.6 0.0 0.014 14.7 0.0 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 OAG39732.1 - 0.0025 17.5 0.0 0.0054 16.4 0.0 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA GIDA PF01134.22 OAG39732.1 - 0.003 16.7 0.1 0.0053 15.9 0.1 1.5 1 1 0 1 1 1 1 Glucose inhibited division protein A Trp_halogenase PF04820.14 OAG39732.1 - 0.0057 15.6 1.2 0.34 9.7 0.0 2.3 2 0 0 2 2 2 1 Tryptophan halogenase HI0933_like PF03486.14 OAG39732.1 - 0.012 14.4 0.0 0.073 11.8 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_9 PF13454.6 OAG39732.1 - 0.015 15.3 0.1 1.9 8.5 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding Thi4 PF01946.17 OAG39732.1 - 0.04 13.1 0.1 0.069 12.4 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.27 OAG39732.1 - 0.15 12.7 0.1 0.71 10.5 0.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF123 PF01986.16 OAG39733.1 - 0.00053 20.4 0.0 0.00077 19.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF123 Rep_2 PF01719.17 OAG39734.1 - 0.066 13.0 0.0 0.093 12.5 0.0 1.1 1 0 0 1 1 1 0 Plasmid replication protein PNP_UDP_1 PF01048.20 OAG39735.1 - 5.3e-13 48.8 0.6 1.2e-12 47.7 0.6 1.5 1 1 0 1 1 1 1 Phosphorylase superfamily SMODS PF18144.1 OAG39735.1 - 0.071 13.3 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Second Messenger Oligonucleotide or Dinucleotide Synthetase domain MFS_1 PF07690.16 OAG39736.1 - 7.7e-30 104.0 27.4 7.7e-30 104.0 27.4 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF1673 PF07895.11 OAG39736.1 - 0.63 9.7 2.7 6.4 6.4 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1673) GPHR_N PF12537.8 OAG39736.1 - 4.8 7.3 4.9 4.5 7.4 0.7 2.6 2 0 0 2 2 2 0 The Golgi pH Regulator (GPHR) Family N-terminal Fungal_trans_2 PF11951.8 OAG39737.1 - 2.9e-08 33.0 0.1 4.8e-08 32.2 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain RNA_pol_Rpb4 PF03874.16 OAG39739.1 - 8e-07 29.4 0.0 0.061 13.6 0.1 2.3 2 0 0 2 2 2 2 RNA polymerase Rpb4 Nucleo_P87 PF07267.11 OAG39739.1 - 0.13 11.1 0.1 0.21 10.4 0.1 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Nop PF01798.18 OAG39740.1 - 1.4e-82 276.6 0.2 1.4e-82 276.6 0.2 2.0 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 OAG39740.1 - 9.5e-23 80.4 3.0 9.5e-23 80.4 3.0 2.4 2 0 0 2 2 2 1 NOP5NT (NUC127) domain HWE_HK PF07536.14 OAG39740.1 - 0.012 16.3 0.2 2.1 9.1 0.1 2.9 2 0 0 2 2 2 0 HWE histidine kinase FAD_binding_3 PF01494.19 OAG39741.1 - 8.3e-24 84.5 0.1 1.4e-23 83.7 0.1 1.4 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 OAG39741.1 - 1.5e-08 34.3 2.8 0.00042 19.7 0.3 2.4 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OAG39741.1 - 4.6e-06 25.9 0.1 8.5e-06 25.1 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.14 OAG39741.1 - 3.3e-05 22.8 1.4 0.02 13.6 1.1 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox PF00070.27 OAG39741.1 - 5.5e-05 23.7 4.3 0.0044 17.5 0.3 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG39741.1 - 6e-05 23.2 0.3 0.00016 21.8 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAG39741.1 - 0.00012 21.8 7.1 0.046 13.3 3.4 2.5 1 1 1 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OAG39741.1 - 0.0011 18.1 2.1 0.0022 17.1 2.1 1.5 1 0 0 1 1 1 1 FAD binding domain Rossmann-like PF10727.9 OAG39741.1 - 0.0021 17.9 1.1 0.0036 17.2 0.2 1.8 2 0 0 2 2 2 1 Rossmann-like domain Amino_oxidase PF01593.24 OAG39741.1 - 0.038 13.3 0.4 2.5 7.3 0.0 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.21 OAG39741.1 - 0.056 12.7 2.9 0.037 13.3 0.8 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 OAG39741.1 - 0.058 13.3 1.5 0.098 12.5 1.5 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Trp_halogenase PF04820.14 OAG39741.1 - 0.075 11.9 0.7 2.3 7.0 0.0 2.2 2 0 0 2 2 2 0 Tryptophan halogenase GIDA PF01134.22 OAG39741.1 - 0.12 11.4 3.2 0.2 10.7 3.2 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Thi4 PF01946.17 OAG39741.1 - 0.13 11.5 0.3 0.38 10.0 0.3 1.7 1 0 0 1 1 1 0 Thi4 family UDPG_MGDP_dh_N PF03721.14 OAG39741.1 - 0.2 11.2 0.3 0.33 10.5 0.3 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox_3 PF13738.6 OAG39741.1 - 0.29 10.3 2.0 0.61 9.3 1.2 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lyase_1 PF00206.20 OAG39742.1 - 1.4e-99 333.4 0.0 1.9e-99 333.0 0.0 1.1 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 OAG39742.1 - 1.3e-16 60.7 0.0 4.3e-16 59.1 0.0 2.0 1 0 0 1 1 1 1 Fumarase C C-terminus Cytochrom_B_N_2 PF13631.6 OAG39742.1 - 0.19 11.7 0.0 0.36 10.8 0.0 1.4 1 0 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB APH PF01636.23 OAG39743.1 - 1.3e-39 136.5 0.0 2e-39 136.0 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 OAG39743.1 - 2.4e-05 23.8 0.0 3.6e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase RIO1 PF01163.22 OAG39743.1 - 6.5e-05 22.6 0.0 0.22 11.1 0.0 2.2 2 0 0 2 2 2 2 RIO1 family Pkinase PF00069.25 OAG39743.1 - 0.0082 15.5 0.0 2.8 7.2 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Sugar_tr PF00083.24 OAG39744.1 - 7.6e-81 272.3 34.6 9.5e-81 271.9 34.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG39744.1 - 1.2e-30 106.7 33.0 1.5e-30 106.3 27.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 OAG39744.1 - 0.0031 16.0 0.8 0.0031 16.0 0.8 2.2 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) GET2 PF08690.10 OAG39744.1 - 0.65 9.6 5.8 0.89 9.2 0.3 2.2 2 0 0 2 2 2 0 GET complex subunit GET2 FAD_binding_3 PF01494.19 OAG39746.1 - 4.7e-51 174.1 0.0 7.8e-51 173.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAG39746.1 - 3.3e-07 30.2 0.6 1.9e-05 24.5 0.6 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 OAG39746.1 - 7.5e-07 28.2 0.0 0.0025 16.6 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox PF00070.27 OAG39746.1 - 1.8e-05 25.2 0.0 0.029 14.9 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAG39746.1 - 0.00033 19.9 0.0 0.032 13.3 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 OAG39746.1 - 0.00048 19.5 0.0 0.067 12.4 0.0 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG39746.1 - 0.00069 19.0 0.0 0.0034 16.7 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 OAG39746.1 - 0.0039 16.9 0.0 0.007 16.0 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Lycopene_cycl PF05834.12 OAG39746.1 - 0.0049 16.0 0.3 0.012 14.7 0.1 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 OAG39746.1 - 0.0062 16.7 0.0 0.02 15.1 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Phage_CI_C PF16452.5 OAG39746.1 - 0.016 15.5 0.0 0.032 14.5 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage CI repressor C-terminal domain Thi4 PF01946.17 OAG39746.1 - 0.022 14.0 0.0 0.039 13.2 0.0 1.3 1 0 0 1 1 1 0 Thi4 family SE PF08491.10 OAG39746.1 - 0.026 13.6 0.0 0.045 12.8 0.0 1.3 1 0 0 1 1 1 0 Squalene epoxidase Fungal_trans PF04082.18 OAG39747.1 - 4.2e-09 35.8 0.0 7.7e-09 35.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Peroxidase_2 PF01328.17 OAG39748.1 - 1.9e-41 142.6 0.0 2.6e-41 142.2 0.0 1.2 1 0 0 1 1 1 1 Peroxidase, family 2 CFEM PF05730.11 OAG39749.1 - 1.4e-05 25.1 6.6 1.4e-05 25.1 6.6 2.1 3 1 0 3 3 3 1 CFEM domain vATP-synt_AC39 PF01992.16 OAG39750.1 - 4.1e-105 352.0 0.0 5.5e-105 351.6 0.0 1.2 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit GMC_oxred_C PF05199.13 OAG39750.1 - 2.2e-30 106.1 0.0 4e-30 105.2 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 OAG39750.1 - 7.3e-27 94.5 0.0 2.1e-23 83.2 0.1 3.1 1 1 0 2 2 2 2 GMC oxidoreductase Pyr_redox_2 PF07992.14 OAG39750.1 - 0.00056 19.2 0.0 0.00096 18.5 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OAG39750.1 - 0.0035 16.5 0.0 0.005 15.9 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 OAG39750.1 - 0.0038 17.4 0.1 0.011 15.9 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 OAG39750.1 - 0.056 12.5 0.1 0.096 11.7 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain FAD_binding_3 PF01494.19 OAG39750.1 - 0.059 12.6 0.1 0.1 11.8 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain RTA1 PF04479.13 OAG39752.1 - 4.6e-57 193.0 2.0 7.1e-57 192.3 2.0 1.3 1 0 0 1 1 1 1 RTA1 like protein TMEM208_SND2 PF05620.11 OAG39752.1 - 0.01 15.6 0.3 0.042 13.6 0.1 2.2 1 1 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 PDR_assoc PF08370.11 OAG39752.1 - 0.052 13.3 0.3 2.8 7.7 0.1 2.5 2 0 0 2 2 2 0 Plant PDR ABC transporter associated Phage_Gp23 PF10669.9 OAG39752.1 - 0.08 13.3 2.7 0.2 12.0 1.0 2.4 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) DUF4834 PF16118.5 OAG39752.1 - 8.2 7.5 7.8 2.1 9.4 0.5 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF4834) Zn_clus PF00172.18 OAG39753.1 - 2.1e-08 34.1 10.7 4e-08 33.2 10.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 OAG39753.1 - 3.6e-05 22.7 0.3 6.7e-05 21.9 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pribosyl_synth PF14572.6 OAG39754.1 - 4.5e-43 147.4 2.1 3.4e-37 128.3 0.9 2.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 OAG39754.1 - 3e-32 111.0 0.0 7.1e-32 109.8 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 OAG39754.1 - 4.3e-14 52.3 0.6 8.1e-14 51.4 0.6 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 OAG39754.1 - 0.0064 16.0 0.2 0.012 15.0 0.2 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase ubiquitin PF00240.23 OAG39755.1 - 0.021 14.6 0.0 0.035 13.9 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin family YukD PF08817.10 OAG39755.1 - 0.073 13.8 0.0 0.13 13.0 0.0 1.4 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD Spc7 PF08317.11 OAG39756.1 - 0.039 12.8 18.0 0.066 12.1 18.0 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein PIN_8 PF18476.1 OAG39756.1 - 0.052 13.4 11.8 0.11 12.3 11.8 1.6 1 0 0 1 1 1 0 PIN like domain Nsp1_C PF05064.13 OAG39756.1 - 0.056 13.2 3.8 0.094 12.5 3.1 1.7 1 1 0 1 1 1 0 Nsp1-like C-terminal region PilJ PF13675.6 OAG39756.1 - 0.11 12.5 1.1 2.2 8.4 0.2 2.7 2 1 1 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF507 PF04368.13 OAG39756.1 - 0.31 10.9 22.3 0.99 9.3 20.0 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF507) SKA1 PF07160.12 OAG39756.1 - 0.34 10.7 15.8 0.23 11.3 13.6 1.8 1 1 0 1 1 1 0 Spindle and kinetochore-associated protein 1 Prominin PF05478.11 OAG39756.1 - 0.91 7.4 8.9 1.3 6.9 8.9 1.2 1 0 0 1 1 1 0 Prominin Mito_fiss_reg PF05308.11 OAG39756.1 - 1 9.4 13.4 0.072 13.2 7.3 1.9 1 1 1 2 2 2 0 Mitochondrial fission regulator Exonuc_VII_L PF02601.15 OAG39756.1 - 1 8.8 7.3 1.6 8.2 7.3 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Tweety PF04906.13 OAG39756.1 - 2.2 6.8 4.9 3.5 6.2 4.9 1.2 1 0 0 1 1 1 0 Tweety WDCP PF15390.6 OAG39756.1 - 3.2 6.0 11.7 4.5 5.5 11.7 1.1 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family Laminin_II PF06009.12 OAG39756.1 - 4.2 7.4 16.8 0.69 9.9 8.3 2.7 2 1 1 3 3 2 0 Laminin Domain II Syntaxin_2 PF14523.6 OAG39756.1 - 4.3 7.8 8.8 16 6.0 7.4 2.2 1 1 1 2 2 2 0 Syntaxin-like protein AATF-Che1 PF13339.6 OAG39756.1 - 5.3 7.7 9.9 12 6.5 9.9 1.7 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor DASH_Duo1 PF08651.10 OAG39756.1 - 5.8 6.8 7.8 0.71 9.7 0.1 3.0 4 0 0 4 4 3 0 DASH complex subunit Duo1 zf-C4H2 PF10146.9 OAG39756.1 - 6.8 6.9 18.1 15 5.8 18.1 1.6 1 1 0 1 1 1 0 Zinc finger-containing protein V_ATPase_I PF01496.19 OAG39756.1 - 7 4.4 13.4 9.7 4.0 13.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ING PF12998.7 OAG39756.1 - 7.3 7.2 10.9 13 6.5 1.4 2.7 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding DUF1664 PF07889.12 OAG39756.1 - 7.6 6.6 18.3 5.1 7.1 5.8 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Pkinase PF00069.25 OAG39758.1 - 6.6e-34 117.5 0.0 1.3e-33 116.5 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG39758.1 - 3.8e-15 55.9 0.0 6.8e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAG39758.1 - 0.0011 17.8 0.0 0.0019 17.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase FHA PF00498.26 OAG39758.1 - 0.009 16.3 0.0 0.024 15.0 0.0 1.7 1 0 0 1 1 1 1 FHA domain ABC1 PF03109.16 OAG39758.1 - 0.091 12.9 0.0 0.3 11.2 0.0 1.8 2 0 0 2 2 2 0 ABC1 family PIG-H PF10181.9 OAG39759.1 - 1.4e-25 89.0 0.6 2.3e-25 88.2 0.6 1.4 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component DUF1275 PF06912.11 OAG39759.1 - 0.066 13.1 0.9 0.1 12.5 0.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1275) DUF4705 PF15788.5 OAG39759.1 - 0.79 10.0 3.5 4.2 7.7 1.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4705) PseudoU_synth_1 PF01416.20 OAG39760.1 - 7e-33 113.3 0.0 2.7e-32 111.5 0.0 2.0 2 0 0 2 2 2 1 tRNA pseudouridine synthase YebO PF13974.6 OAG39760.1 - 0.16 12.0 0.0 0.33 11.0 0.0 1.5 1 0 0 1 1 1 0 YebO-like protein Exonuc_VII_S PF02609.16 OAG39761.1 - 0.033 14.2 1.3 1.1 9.4 0.1 3.9 3 0 0 3 3 3 0 Exonuclease VII small subunit ChAPs PF09295.10 OAG39762.1 - 1.5e-149 498.3 0.0 2e-149 498.0 0.0 1.1 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_2 PF07719.17 OAG39762.1 - 0.00084 19.3 1.5 0.065 13.4 0.6 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_15 PF13429.6 OAG39762.1 - 0.0014 17.9 1.6 0.16 11.2 0.2 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 OAG39762.1 - 0.0019 18.7 2.3 0.27 11.7 0.0 3.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 OAG39762.1 - 0.0035 18.0 4.1 3 8.9 0.1 4.5 2 1 3 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 OAG39762.1 - 0.0092 15.8 0.6 2.4 8.1 0.2 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 OAG39762.1 - 0.012 15.8 2.6 1.2 9.4 0.2 3.5 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 OAG39762.1 - 0.03 14.5 0.0 1.9 8.9 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 OAG39762.1 - 0.037 14.1 1.9 28 5.1 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat UQ_con PF00179.26 OAG39763.1 - 1.1e-37 128.8 0.0 1.6e-28 99.1 0.1 2.0 1 1 1 2 2 2 2 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OAG39763.1 - 1.2e-06 28.2 0.0 1.7e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 OAG39763.1 - 0.00089 19.5 0.0 0.00093 19.5 0.0 1.3 1 0 0 1 1 1 1 RWD domain Brix PF04427.18 OAG39764.1 - 3.8e-50 170.7 0.1 5.3e-50 170.2 0.1 1.2 1 0 0 1 1 1 1 Brix domain TFIIA PF03153.13 OAG39764.1 - 0.00093 19.3 23.2 0.0014 18.8 23.2 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF1168 PF06658.12 OAG39764.1 - 1.7 8.4 29.4 0.71 9.7 12.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1168) Sugar_tr PF00083.24 OAG39766.1 - 2.3e-35 122.4 14.5 3.8e-35 121.6 14.5 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG39766.1 - 2.9e-20 72.5 42.5 3.3e-19 69.0 22.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2721 PF11026.8 OAG39766.1 - 7.3 6.5 12.4 0.17 11.8 0.2 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF2721) Zn_clus PF00172.18 OAG39767.1 - 7.4e-10 38.8 7.1 1.3e-09 38.0 7.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAG39767.1 - 1.1e-05 24.6 1.6 0.00017 20.7 1.6 2.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Glyco_tranf_2_3 PF13641.6 OAG39767.1 - 0.072 13.0 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Phosphodiest PF01663.22 OAG39768.1 - 4.6e-31 108.7 0.0 9.6e-31 107.6 0.0 1.6 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase HD PF01966.22 OAG39768.1 - 1.2e-05 25.5 0.0 2.4e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 HD domain HD_4 PF13328.6 OAG39768.1 - 0.04 13.7 0.1 0.078 12.7 0.1 1.4 1 0 0 1 1 1 0 HD domain PhyH PF05721.13 OAG39769.1 - 2.4e-30 106.4 0.1 3.3e-30 105.9 0.1 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 OAG39769.1 - 0.00016 22.0 0.0 0.00038 20.8 0.0 1.7 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase 2OG-FeII_Oxy_3 PF13640.6 OAG39769.1 - 0.014 16.3 0.1 0.034 15.0 0.1 1.7 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily UCMA PF17085.5 OAG39769.1 - 0.17 11.9 0.1 0.42 10.6 0.1 1.6 1 0 0 1 1 1 0 Unique cartilage matrix associated protein OCD_Mu_crystall PF02423.15 OAG39770.1 - 1.8e-09 37.0 0.0 1e-08 34.5 0.0 2.0 1 1 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.20 OAG39770.1 - 1.4e-08 34.9 0.0 8.4e-07 29.1 0.0 2.3 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 OAG39770.1 - 0.00017 21.8 0.0 0.00033 20.9 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain GFO_IDH_MocA PF01408.22 OAG39770.1 - 0.013 16.3 0.0 0.037 14.8 0.0 1.8 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold Tir_receptor_N PF07490.11 OAG39770.1 - 0.099 12.5 1.1 0.17 11.7 1.1 1.5 1 1 0 1 1 1 0 Translocated intimin receptor (Tir) N-terminus HEM4 PF02602.15 OAG39770.1 - 0.11 11.8 0.1 0.36 10.1 0.1 1.8 1 1 0 1 1 1 0 Uroporphyrinogen-III synthase HemD F420_oxidored PF03807.17 OAG39770.1 - 0.12 13.0 0.0 0.41 11.3 0.0 1.9 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_7 PF13241.6 OAG39770.1 - 0.16 12.4 0.0 0.51 10.8 0.0 1.8 2 0 0 2 2 2 0 Putative NAD(P)-binding Aa_trans PF01490.18 OAG39771.1 - 7.3e-41 140.2 28.3 8.4e-41 140.0 28.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein MFS_1 PF07690.16 OAG39772.1 - 1.1e-39 136.4 60.9 1.1e-39 136.4 60.9 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 OAG39772.1 - 9.1e-13 47.5 30.2 1.3e-12 47.0 30.2 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 OAG39772.1 - 1.2e-07 30.9 17.8 1.2e-07 30.9 17.8 3.2 2 1 1 3 3 3 2 Sugar (and other) transporter MFS_2 PF13347.6 OAG39772.1 - 7.5e-05 21.5 41.3 0.0018 16.9 7.7 2.7 2 1 0 2 2 2 2 MFS/sugar transport protein p450 PF00067.22 OAG39773.1 - 6.6e-63 213.0 0.0 9.7e-63 212.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Hira PF07569.11 OAG39773.1 - 0.17 11.6 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 TUP1-like enhancer of split Polyketide_cyc2 PF10604.9 OAG39774.1 - 8.9e-08 32.5 0.0 1e-07 32.3 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 OAG39774.1 - 0.12 12.6 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport Amidohydro_2 PF04909.14 OAG39775.1 - 1.4e-46 159.6 0.1 1.7e-46 159.3 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase Beta-lactamase PF00144.24 OAG39776.1 - 7.1e-36 124.1 0.0 9.2e-36 123.7 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase YCII PF03795.14 OAG39777.1 - 0.01 16.2 0.0 0.013 15.9 0.0 1.2 1 0 0 1 1 1 0 YCII-related domain Fungal_trans PF04082.18 OAG39778.1 - 6e-14 51.7 2.9 1.6e-13 50.3 0.0 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG39778.1 - 2.3e-09 37.2 14.0 4.2e-09 36.4 14.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NmrA PF05368.13 OAG39779.1 - 8.9e-28 97.4 0.3 1.2e-27 97.0 0.3 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG39779.1 - 7.2e-20 71.7 0.2 1.2e-19 70.9 0.2 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 OAG39779.1 - 6.1e-08 33.0 0.8 1.4e-07 31.8 0.1 1.9 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 OAG39779.1 - 9.2e-08 32.6 0.2 1.9e-07 31.6 0.2 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.21 OAG39779.1 - 7.1e-06 25.6 0.4 3.7e-05 23.3 0.3 2.2 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OAG39779.1 - 9.3e-05 21.6 1.0 0.00021 20.4 0.2 1.9 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Shikimate_DH PF01488.20 OAG39779.1 - 0.00016 21.7 0.1 0.00029 20.9 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DapB_N PF01113.20 OAG39779.1 - 0.0012 19.0 0.3 0.0024 18.0 0.3 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus FliG_C PF01706.16 OAG39779.1 - 0.011 15.9 0.0 0.8 9.9 0.0 2.5 2 0 0 2 2 2 0 FliG C-terminal domain p450 PF00067.22 OAG39780.1 - 1.2e-66 225.3 0.0 1.7e-66 224.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Amidohydro_1 PF01979.20 OAG39781.1 - 2.6e-25 89.5 0.2 3.6e-24 85.7 0.2 2.1 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 OAG39781.1 - 2.7e-14 53.5 0.1 6.9e-09 35.7 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family FAA_hydrolase PF01557.18 OAG39782.1 - 1.6e-59 201.2 0.0 1.9e-59 201.0 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Glyoxalase PF00903.25 OAG39783.1 - 2e-14 53.9 3.0 1.7e-10 41.2 1.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily adh_short_C2 PF13561.6 OAG39784.1 - 6.7e-47 160.0 0.0 1.4e-46 158.9 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG39784.1 - 3.9e-38 130.9 0.0 5e-38 130.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG39784.1 - 0.00015 21.7 0.0 0.0014 18.6 0.0 2.1 1 1 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 OAG39784.1 - 0.096 12.0 0.0 3 7.1 0.0 2.3 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain p450 PF00067.22 OAG39785.1 - 1.1e-33 116.7 0.0 1.7e-33 116.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 AbiJ_NTD5 PF18865.1 OAG39785.1 - 0.093 12.6 0.2 0.34 10.8 0.0 2.0 2 0 0 2 2 2 0 AbiJ N-terminal domain 5 FAD_binding_3 PF01494.19 OAG39786.1 - 1.1e-16 61.0 1.5 1.5e-14 54.1 0.1 2.5 2 1 0 2 2 2 2 FAD binding domain SE PF08491.10 OAG39786.1 - 0.00013 21.2 0.0 0.06 12.4 0.0 2.3 2 0 0 2 2 2 2 Squalene epoxidase DAO PF01266.24 OAG39786.1 - 0.00017 21.3 3.8 0.00017 21.3 3.8 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAG39786.1 - 0.0074 16.5 0.9 0.021 15.0 0.9 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 OAG39786.1 - 0.037 13.1 1.2 0.072 12.1 0.5 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein HI0933_like PF03486.14 OAG39786.1 - 0.057 12.1 0.2 0.098 11.3 0.2 1.3 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_2 PF00890.24 OAG39786.1 - 0.1 11.7 2.0 0.16 11.0 2.0 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.14 OAG39786.1 - 0.1 11.8 0.3 0.15 11.2 0.3 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 OAG39787.1 - 7.7e-21 74.7 0.7 3.5e-20 72.6 0.7 1.9 1 1 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 OAG39787.1 - 2.4e-07 30.2 0.1 4e-07 29.5 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAG39787.1 - 4.3e-06 26.6 0.5 1.9e-05 24.4 0.1 2.1 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAG39787.1 - 6.1e-06 26.4 0.1 5.3e-05 23.4 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAG39787.1 - 7.6e-06 25.4 0.3 2.3e-05 23.8 0.3 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OAG39787.1 - 6.2e-05 22.3 0.2 0.00099 18.3 0.1 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 OAG39787.1 - 0.00014 21.3 0.0 0.00022 20.6 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAG39787.1 - 0.00026 19.8 0.2 0.00051 18.9 0.1 1.5 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 OAG39787.1 - 0.0044 16.4 0.2 0.0094 15.3 0.2 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.14 OAG39787.1 - 0.035 13.7 0.1 0.059 12.9 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Thi4 PF01946.17 OAG39787.1 - 0.036 13.3 0.0 0.068 12.4 0.0 1.4 1 0 0 1 1 1 0 Thi4 family AlaDh_PNT_C PF01262.21 OAG39787.1 - 0.046 13.0 0.0 0.079 12.2 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 OAG39787.1 - 0.049 14.2 0.3 0.14 12.7 0.3 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OAG39787.1 - 0.14 11.2 1.4 1.3 8.0 0.0 2.5 3 0 0 3 3 3 0 Lycopene cyclase protein 3HCDH_N PF02737.18 OAG39787.1 - 0.18 11.6 0.2 0.31 10.9 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Cupin_2 PF07883.11 OAG39789.1 - 1.9e-13 49.9 0.4 3.3e-13 49.2 0.4 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 OAG39789.1 - 0.0028 17.3 0.0 0.0039 16.8 0.0 1.2 1 0 0 1 1 1 1 Cupin 3-HAO PF06052.12 OAG39789.1 - 0.092 12.4 0.0 0.39 10.3 0.0 1.8 1 1 1 2 2 2 0 3-hydroxyanthranilic acid dioxygenase Cupin_6 PF12852.7 OAG39789.1 - 0.18 11.5 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 Cupin Flavin_Reduct PF01613.18 OAG39790.1 - 1e-15 58.1 0.0 1.4e-15 57.7 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain Fungal_trans PF04082.18 OAG39791.1 - 7.4e-11 41.6 3.6 4.5e-10 39.0 0.1 2.3 1 1 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG39791.1 - 3.7e-08 33.4 13.8 7.7e-08 32.3 13.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.22 OAG39792.1 - 2.5e-67 227.7 0.0 3.1e-67 227.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Ring_hydroxyl_A PF00848.19 OAG39793.1 - 2.6e-25 89.7 2.3 8.7e-13 48.7 1.1 2.3 1 1 1 2 2 2 2 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.26 OAG39793.1 - 1.3e-14 53.9 0.0 2.4e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Sugar_tr PF00083.24 OAG39794.1 - 7.7e-73 245.9 19.1 1e-72 245.5 19.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG39794.1 - 2.9e-25 89.0 33.0 5.4e-25 88.1 31.2 2.2 1 1 2 3 3 3 1 Major Facilitator Superfamily Phage_holin_3_2 PF04550.12 OAG39794.1 - 0.012 16.2 0.5 0.045 14.3 0.5 2.0 1 0 0 1 1 1 0 Phage holin family 2 Apolipoprotein PF01442.18 OAG39795.1 - 0.0013 18.6 0.4 0.043 13.7 0.4 2.1 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF883 PF05957.13 OAG39795.1 - 0.19 12.4 2.5 0.18 12.4 0.6 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Amidohydro_3 PF07969.11 OAG39796.1 - 3e-79 267.7 1.8 3.5e-79 267.5 1.8 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 OAG39796.1 - 1.3e-16 60.8 0.2 1.4e-12 47.7 0.1 3.4 2 1 0 2 2 2 2 Amidohydrolase family DUF2087 PF09860.9 OAG39796.1 - 0.039 14.1 0.0 0.098 12.8 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2087) Glyco_hydro_43 PF04616.14 OAG39797.1 - 2.1e-27 96.2 2.8 7.1e-19 68.2 0.5 2.4 2 1 0 2 2 2 2 Glycosyl hydrolases family 43 FAD_binding_3 PF01494.19 OAG39798.1 - 2e-20 73.3 0.1 1.2e-19 70.8 0.1 1.9 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 OAG39798.1 - 1.8e-08 34.5 0.4 3.6e-08 33.5 0.4 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAG39798.1 - 6.7e-06 25.9 1.0 2.3e-05 24.2 1.1 1.8 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG39798.1 - 3.4e-05 23.2 0.1 0.00023 20.5 0.2 2.0 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAG39798.1 - 7.5e-05 22.0 0.5 0.00012 21.3 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 OAG39798.1 - 0.00072 20.1 0.1 0.0014 19.1 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.21 OAG39798.1 - 0.0026 17.2 0.2 0.0046 16.4 0.2 1.3 1 0 0 1 1 1 1 ThiF family Thi4 PF01946.17 OAG39798.1 - 0.011 15.0 0.1 0.019 14.2 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.14 OAG39798.1 - 0.016 14.1 0.2 0.023 13.6 0.2 1.2 1 0 0 1 1 1 0 Tryptophan halogenase GIDA PF01134.22 OAG39798.1 - 0.024 13.7 1.7 0.035 13.2 1.7 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 OAG39798.1 - 0.025 13.9 0.8 0.039 13.2 0.8 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 OAG39798.1 - 0.033 13.2 0.0 0.071 12.2 0.0 1.6 1 1 0 1 1 1 0 Squalene epoxidase Shikimate_DH PF01488.20 OAG39798.1 - 0.045 13.8 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.14 OAG39798.1 - 0.067 12.8 0.2 0.13 11.8 0.2 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Amino_oxidase PF01593.24 OAG39798.1 - 0.095 12.0 0.5 0.15 11.3 0.1 1.6 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase HI0933_like PF03486.14 OAG39798.1 - 0.36 9.5 1.3 0.51 9.0 1.3 1.2 1 0 0 1 1 1 0 HI0933-like protein DUF2235 PF09994.9 OAG39800.1 - 2.1e-62 211.1 0.0 2.6e-62 210.8 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) SNF PF00209.18 OAG39801.1 - 2.6e-73 247.5 34.9 3.4e-45 154.7 18.3 2.4 3 0 0 3 3 3 2 Sodium:neurotransmitter symporter family DUF3810 PF12725.7 OAG39801.1 - 0.34 10.2 1.0 0.87 8.9 1.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Sugar_tr PF00083.24 OAG39802.1 - 1.3e-81 274.7 18.4 1.5e-81 274.6 18.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG39802.1 - 3.7e-22 78.7 25.5 3.7e-22 78.7 25.5 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily PUCC PF03209.15 OAG39802.1 - 0.079 11.9 15.5 0.016 14.2 12.0 1.6 2 0 0 2 2 2 0 PUCC protein Glyco_hydro_5_C PF18564.1 OAG39803.1 - 9.4e-24 83.8 0.1 2e-23 82.7 0.1 1.6 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Cellulase PF00150.18 OAG39803.1 - 6.3e-15 55.3 0.9 4.2e-11 42.8 0.3 2.6 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_35 PF01301.19 OAG39803.1 - 0.0044 16.7 0.1 0.0079 15.9 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.15 OAG39803.1 - 0.0047 16.3 0.3 0.97 8.7 0.1 2.2 2 0 0 2 2 2 2 Beta-galactosidase Pkinase PF00069.25 OAG39804.1 - 1.5e-16 60.6 0.0 1.9e-16 60.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG39804.1 - 4.7e-07 29.3 0.0 6.8e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Methyltransf_25 PF13649.6 OAG39805.1 - 4.5e-15 56.1 0.0 9.8e-15 55.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG39805.1 - 6.1e-13 49.2 0.0 1.2e-12 48.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAG39805.1 - 5.3e-12 45.6 0.0 1e-11 44.7 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 OAG39805.1 - 2.1e-10 40.7 0.0 2.8e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG39805.1 - 1.3e-08 34.8 0.0 1.9e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG39805.1 - 1.1e-07 32.5 0.0 2.1e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 OAG39805.1 - 0.0028 17.1 0.0 0.013 15.0 0.0 1.9 1 1 0 2 2 2 1 Putative methyltransferase MTS PF05175.14 OAG39805.1 - 0.0056 16.2 0.0 0.014 14.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase small domain TPR_1 PF00515.28 OAG39806.1 - 8e-28 95.1 28.1 0.00023 20.8 0.1 12.9 14 0 0 14 14 14 7 Tetratricopeptide repeat TPR_16 PF13432.6 OAG39806.1 - 2.1e-27 95.5 49.6 4.2e-06 27.3 0.1 12.4 9 4 1 12 12 11 7 Tetratricopeptide repeat TPR_17 PF13431.6 OAG39806.1 - 2.9e-25 86.8 20.5 0.0053 17.0 0.0 14.7 15 1 1 16 16 14 5 Tetratricopeptide repeat TPR_2 PF07719.17 OAG39806.1 - 1.4e-24 84.2 58.0 0.00039 20.3 0.1 17.2 20 0 0 20 20 18 7 Tetratricopeptide repeat TPR_8 PF13181.6 OAG39806.1 - 9.2e-24 81.6 31.6 0.0019 18.3 0.0 14.3 15 0 0 15 15 13 6 Tetratricopeptide repeat TPR_11 PF13414.6 OAG39806.1 - 3.7e-22 77.7 21.3 0.001 18.7 0.0 10.8 12 0 0 12 12 11 6 TPR repeat TPR_14 PF13428.6 OAG39806.1 - 1.4e-21 75.3 56.8 0.0012 19.5 0.1 18.6 14 4 6 20 20 18 5 Tetratricopeptide repeat TPR_19 PF14559.6 OAG39806.1 - 4.3e-18 65.6 51.0 1.4e-06 28.7 0.8 11.6 11 2 3 14 14 12 8 Tetratricopeptide repeat TPR_7 PF13176.6 OAG39806.1 - 5.7e-16 57.3 12.4 0.022 14.7 0.1 9.2 8 2 2 10 10 9 4 Tetratricopeptide repeat TPR_12 PF13424.6 OAG39806.1 - 9.1e-14 51.5 44.7 0.0015 18.8 0.5 13.3 10 4 5 15 15 15 6 Tetratricopeptide repeat TPR_6 PF13174.6 OAG39806.1 - 3.2e-07 30.6 36.8 0.35 11.6 0.1 14.5 17 0 0 17 17 14 2 Tetratricopeptide repeat TPR_9 PF13371.6 OAG39806.1 - 2.1e-05 24.6 26.0 0.054 13.7 0.3 8.9 9 1 1 10 10 10 3 Tetratricopeptide repeat TPR_22 PF18833.1 OAG39806.1 - 0.041 14.0 0.0 0.15 12.2 0.0 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_10 PF13374.6 OAG39806.1 - 0.092 12.7 20.4 1.8 8.6 0.2 8.0 8 0 0 8 8 7 0 Tetratricopeptide repeat ANAPC3 PF12895.7 OAG39806.1 - 0.1 12.9 29.1 0.86 9.9 0.1 8.4 9 1 0 9 9 8 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.14 OAG39806.1 - 0.48 11.2 33.4 0.33 11.7 0.3 10.1 11 0 0 11 11 8 0 Tetratricopeptide repeat TPR_20 PF14561.6 OAG39806.1 - 1.1 9.6 34.4 0.2 12.0 0.3 8.6 7 3 1 8 8 8 0 Tetratricopeptide repeat RPN6_N PF18055.1 OAG39806.1 - 1.6 9.1 6.2 1.5 9.2 0.3 3.8 4 0 0 4 4 4 0 26S proteasome regulatory subunit RPN6 N-terminal domain RMI1_N PF08585.12 OAG39807.1 - 2.1e-61 207.5 0.0 2.9e-61 207.0 0.0 1.2 1 0 0 1 1 1 1 RecQ mediated genome instability protein adh_short PF00106.25 OAG39808.1 - 7.6e-44 149.5 0.2 1.2e-43 148.9 0.2 1.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG39808.1 - 6.4e-39 133.9 0.2 1.4e-37 129.5 0.2 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG39808.1 - 1.5e-07 31.5 0.3 1.5e-07 31.5 0.3 2.0 1 1 0 2 2 2 1 KR domain Epimerase PF01370.21 OAG39808.1 - 0.073 12.5 0.1 0.11 11.9 0.1 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family ApbA PF02558.16 OAG39808.1 - 0.083 12.5 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.27 OAG39808.1 - 0.11 13.1 0.2 0.27 11.8 0.2 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 OAG39808.1 - 0.12 12.2 0.2 0.22 11.4 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 OAG39808.1 - 0.14 12.2 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF2183 PF09949.9 OAG39809.1 - 2.1e-21 76.1 0.1 4.8e-21 75.0 0.1 1.6 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2183) PAN_1 PF00024.26 OAG39810.1 - 4.3e-05 23.4 0.1 0.63 10.0 0.0 3.1 2 0 0 2 2 2 2 PAN domain ABC_membrane PF00664.23 OAG39811.1 - 8.2e-80 268.4 40.0 9.9e-41 140.2 14.6 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 OAG39811.1 - 9.3e-65 217.3 0.0 9.3e-34 116.9 0.0 2.9 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 OAG39811.1 - 1.5e-14 54.0 6.0 1e-05 25.1 1.0 4.7 4 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 OAG39811.1 - 5.1e-10 39.8 0.0 0.00052 20.3 0.0 3.5 3 1 0 3 3 3 2 AAA domain AAA_16 PF13191.6 OAG39811.1 - 4.2e-08 33.8 1.3 0.0015 18.9 0.0 3.1 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 OAG39811.1 - 2.9e-07 30.1 0.5 0.0018 17.9 0.2 2.8 3 0 0 3 3 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 OAG39811.1 - 3.3e-07 30.4 0.0 0.011 15.7 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_21 PF13304.6 OAG39811.1 - 4.2e-07 30.1 0.0 0.89 9.3 0.0 3.9 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 OAG39811.1 - 6.7e-06 26.0 0.0 0.18 11.5 0.0 3.3 2 1 0 2 2 2 2 AAA domain AAA_7 PF12775.7 OAG39811.1 - 1.1e-05 25.0 0.0 0.13 11.8 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_23 PF13476.6 OAG39811.1 - 2e-05 25.2 0.1 0.22 12.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 OAG39811.1 - 3e-05 23.9 0.0 0.088 12.5 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA PF00004.29 OAG39811.1 - 7.1e-05 23.2 4.1 0.65 10.4 0.5 4.7 4 1 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 OAG39811.1 - 7.9e-05 22.3 0.1 0.29 10.7 0.0 3.0 4 0 0 4 4 2 2 AAA domain AAA_5 PF07728.14 OAG39811.1 - 0.00017 21.6 0.0 0.86 9.6 0.0 3.1 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 OAG39811.1 - 0.00017 21.8 0.0 1.1 9.4 0.0 2.9 2 0 0 2 2 2 2 AAA domain Rad17 PF03215.15 OAG39811.1 - 0.00027 20.9 0.0 0.13 12.2 0.0 2.7 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_18 PF13238.6 OAG39811.1 - 0.00028 21.5 0.0 0.87 10.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 OAG39811.1 - 0.00045 20.5 0.0 0.31 11.3 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_24 PF13479.6 OAG39811.1 - 0.0013 18.5 0.0 0.53 10.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain ABC_ATPase PF09818.9 OAG39811.1 - 0.0026 16.6 0.3 1.1 8.0 0.0 2.8 3 0 0 3 3 3 1 Predicted ATPase of the ABC class IstB_IS21 PF01695.17 OAG39811.1 - 0.0026 17.5 0.3 12 5.5 0.0 3.8 4 0 0 4 4 4 0 IstB-like ATP binding protein SbcCD_C PF13558.6 OAG39811.1 - 0.004 17.3 1.8 2.3 8.5 0.1 3.8 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit SRP54 PF00448.22 OAG39811.1 - 0.0092 15.6 0.0 4.9 6.7 0.0 2.5 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain NB-ARC PF00931.22 OAG39811.1 - 0.01 15.1 0.0 1.6 7.8 0.0 2.7 3 0 0 3 3 3 0 NB-ARC domain RNA_helicase PF00910.22 OAG39811.1 - 0.021 15.2 0.0 7.1 7.1 0.0 2.7 2 0 0 2 2 2 0 RNA helicase G-alpha PF00503.20 OAG39811.1 - 0.026 13.7 0.0 5.3 6.1 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit ATP_bind_1 PF03029.17 OAG39811.1 - 0.026 14.3 0.0 1.9 8.2 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 OAG39811.1 - 0.049 12.9 0.0 12 5.1 0.0 3.0 3 0 0 3 3 3 0 Zeta toxin PRK PF00485.18 OAG39811.1 - 0.051 13.3 0.0 3.2 7.4 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family MMR_HSR1 PF01926.23 OAG39811.1 - 0.074 13.1 0.1 16 5.6 0.0 2.8 3 0 0 3 3 2 0 50S ribosome-binding GTPase AAA_17 PF13207.6 OAG39811.1 - 0.1 13.1 0.0 28 5.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 OAG39811.1 - 0.11 12.4 0.0 5.4 6.9 0.0 2.4 2 0 0 2 2 2 0 Adenylylsulphate kinase PNP_UDP_1 PF01048.20 OAG39813.1 - 5.2e-10 39.0 0.1 1.2e-09 37.8 0.1 1.6 1 1 0 1 1 1 1 Phosphorylase superfamily Alpha_GJ PF03229.13 OAG39813.1 - 0.026 15.1 0.9 0.052 14.1 0.1 1.8 2 0 0 2 2 2 0 Alphavirus glycoprotein J Clathrin-link PF09268.10 OAG39814.1 - 0.16 11.4 0.1 0.3 10.5 0.1 1.5 1 0 0 1 1 1 0 Clathrin, heavy-chain linker Fungal_trans PF04082.18 OAG39815.1 - 7.2e-27 94.1 0.2 1.7e-26 92.8 0.2 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG39815.1 - 1.8e-08 34.3 11.9 3.2e-08 33.6 11.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyoxalase PF00903.25 OAG39816.1 - 4.6e-11 43.0 0.8 1.1e-07 32.1 0.1 2.4 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 OAG39816.1 - 0.09 13.1 0.1 14 6.0 0.0 3.1 2 2 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily FAD_binding_3 PF01494.19 OAG39817.1 - 4.6e-69 233.3 0.0 2.2e-68 231.1 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain FAD_binding_2 PF00890.24 OAG39817.1 - 1.8e-06 27.3 0.0 0.0001 21.6 0.0 2.5 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 OAG39817.1 - 6.3e-06 26.0 0.1 0.00074 19.2 0.0 2.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG39817.1 - 6.5e-06 25.6 0.0 0.00027 20.3 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAG39817.1 - 0.00024 20.0 0.0 0.0004 19.2 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.6 OAG39817.1 - 0.00045 20.4 0.0 0.0015 18.7 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 OAG39817.1 - 0.00046 19.4 0.0 0.00088 18.5 0.0 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 OAG39817.1 - 0.00048 19.6 0.0 0.0016 17.9 0.1 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 OAG39817.1 - 0.00094 18.5 0.1 0.0021 17.4 0.0 1.6 2 0 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.6 OAG39817.1 - 0.0039 16.5 0.0 0.012 14.8 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAG39817.1 - 0.0095 15.9 0.0 2.1 8.3 0.0 2.6 2 0 0 2 2 2 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 OAG39817.1 - 0.023 13.8 0.1 0.061 12.4 0.0 1.7 3 0 0 3 3 3 0 Lycopene cyclase protein Pyr_redox_2 PF07992.14 OAG39819.1 - 1.5e-22 80.2 0.3 6.9e-17 61.6 0.0 3.1 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG39819.1 - 2e-18 66.7 0.0 1.3e-16 60.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 OAG39819.1 - 1.5e-17 63.2 0.0 1.8e-16 59.7 0.0 2.2 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 OAG39819.1 - 8.3e-16 58.0 0.1 1.5e-11 44.1 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 OAG39819.1 - 4.2e-12 46.5 0.1 0.0033 18.0 0.0 3.6 3 0 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 OAG39819.1 - 7.9e-09 35.2 0.2 9.3e-07 28.4 0.1 2.4 1 1 1 2 2 2 1 FAD binding domain Shikimate_DH PF01488.20 OAG39819.1 - 2.1e-08 34.3 1.1 0.0015 18.6 0.0 3.3 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.14 OAG39819.1 - 1e-06 27.8 0.0 0.00019 20.3 0.1 2.5 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_9 PF13454.6 OAG39819.1 - 7.4e-06 26.0 1.5 0.34 10.9 0.0 3.8 3 1 1 4 4 4 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 OAG39819.1 - 7.9e-06 26.0 0.0 0.00017 21.8 0.0 2.8 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAG39819.1 - 2.5e-05 24.0 0.3 0.39 10.2 0.0 3.4 2 1 1 3 3 3 2 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.19 OAG39819.1 - 4.2e-05 23.0 0.1 0.089 12.1 0.0 2.3 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GIDA PF01134.22 OAG39819.1 - 5.1e-05 22.5 0.1 0.042 12.9 0.0 3.1 3 1 0 3 3 3 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 OAG39819.1 - 7e-05 22.1 0.0 0.012 14.7 0.1 2.4 2 0 0 2 2 2 1 FAD binding domain IlvN PF07991.12 OAG39819.1 - 0.00013 21.6 0.5 0.021 14.4 0.1 2.6 2 1 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain Lycopene_cycl PF05834.12 OAG39819.1 - 0.00089 18.4 0.6 0.066 12.2 0.0 2.7 4 0 0 4 4 4 1 Lycopene cyclase protein 3HCDH_N PF02737.18 OAG39819.1 - 0.0012 18.7 0.1 0.1 12.5 0.0 2.4 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 OAG39819.1 - 0.0014 19.2 0.5 0.092 13.3 0.1 2.8 3 0 0 3 3 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_7 PF13241.6 OAG39819.1 - 0.0034 17.8 0.0 0.51 10.8 0.1 2.6 2 1 0 2 2 2 1 Putative NAD(P)-binding ThiF PF00899.21 OAG39819.1 - 0.0047 16.3 0.1 2.2 7.6 0.1 2.2 2 0 0 2 2 2 2 ThiF family FAD_oxidored PF12831.7 OAG39819.1 - 0.0059 16.0 0.1 0.024 14.0 0.1 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase TrkA_N PF02254.18 OAG39819.1 - 0.039 14.2 0.3 2.7 8.3 0.0 3.0 4 0 0 4 4 3 0 TrkA-N domain Trp_halogenase PF04820.14 OAG39819.1 - 0.049 12.5 2.0 6.5 5.5 0.1 2.9 3 0 0 3 3 3 0 Tryptophan halogenase AF-4 PF05110.13 OAG39820.1 - 0.08 11.0 31.2 0.087 10.9 31.2 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein CDC27 PF09507.10 OAG39820.1 - 0.087 12.2 29.6 0.1 12.0 29.6 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Paramyxo_NS_C PF02725.14 OAG39820.1 - 1.5 8.9 4.0 2.8 8.1 4.0 1.5 1 0 0 1 1 1 0 Non-structural protein C LCD1 PF09798.9 OAG39820.1 - 4.6 5.6 8.0 6 5.3 8.0 1.3 1 0 0 1 1 1 0 DNA damage checkpoint protein DUF4551 PF15087.6 OAG39820.1 - 9 5.0 15.1 12 4.6 15.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Evr1_Alr PF04777.13 OAG39821.1 - 1.6e-14 54.1 0.2 7.9e-14 51.9 0.0 1.9 2 0 0 2 2 2 1 Erv1 / Alr family DUF3431 PF11913.8 OAG39822.1 - 9e-61 205.4 0.0 1.1e-60 205.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) HAD_SAK_1 PF10307.9 OAG39823.1 - 7.6e-72 241.4 0.0 1.2e-71 240.7 0.0 1.3 1 0 0 1 1 1 1 HAD domain family 1 in Swiss Army Knife RNA repair proteins Abhydrolase_1 PF00561.20 OAG39824.1 - 1.6e-23 83.7 0.2 3.2e-16 59.7 0.3 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG39824.1 - 3.7e-20 73.5 5.0 4.5e-20 73.2 5.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG39824.1 - 6.4e-14 51.8 1.2 5.2e-13 48.8 1.2 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 OAG39824.1 - 0.00012 20.8 0.0 0.047 12.4 0.0 2.1 2 0 0 2 2 2 2 Ndr family Abhydrolase_4 PF08386.10 OAG39824.1 - 0.031 14.4 0.0 1.4 9.1 0.0 2.2 2 0 0 2 2 2 0 TAP-like protein Peptidase_S9 PF00326.21 OAG39824.1 - 0.055 12.9 0.5 0.94 8.9 0.9 2.4 2 1 1 3 3 3 0 Prolyl oligopeptidase family FSH1 PF03959.13 OAG39824.1 - 0.083 12.5 0.0 1.3 8.7 0.0 2.1 2 0 0 2 2 2 0 Serine hydrolase (FSH1) DUF2920 PF11144.8 OAG39824.1 - 0.28 10.3 0.2 0.39 9.8 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) Fungal_trans PF04082.18 OAG39825.1 - 1.1e-15 57.4 0.9 1.5e-15 57.0 0.2 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG39825.1 - 8.2e-05 22.7 11.8 0.00013 22.0 11.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain iPGM_N PF06415.13 OAG39826.1 - 1.4e-77 260.0 0.0 2e-77 259.5 0.0 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Metalloenzyme PF01676.18 OAG39826.1 - 4.7e-72 242.3 0.0 5.4e-72 242.1 0.0 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 OAG39826.1 - 2.8e-06 27.0 0.0 7.6e-05 22.2 0.0 2.7 2 1 0 2 2 2 1 Sulfatase Phosphodiest PF01663.22 OAG39826.1 - 2.9e-06 27.1 0.0 6.3e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Alk_phosphatase PF00245.20 OAG39826.1 - 0.0036 16.3 0.1 0.027 13.4 0.0 2.0 2 0 0 2 2 2 1 Alkaline phosphatase Methyltransf_31 PF13847.6 OAG39826.1 - 0.15 11.9 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Aldedh PF00171.22 OAG39827.1 - 2e-12 46.4 8.5 7e-10 38.0 4.6 2.8 2 1 0 2 2 2 2 Aldehyde dehydrogenase family TubC_N PF18563.1 OAG39827.1 - 0.037 14.0 0.9 2.7 8.1 0.1 2.8 2 1 1 3 3 3 0 TubC N-terminal docking domain Ribosomal_L18 PF17135.4 OAG39828.1 - 1.2e-92 308.4 3.2 1.4e-92 308.3 3.2 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 OAG39828.1 - 0.00013 22.6 2.1 0.00014 22.6 0.1 2.1 2 1 0 2 2 2 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A tRNA_anti-like PF12869.7 OAG39828.1 - 0.027 14.1 0.0 0.044 13.4 0.0 1.3 1 0 0 1 1 1 0 tRNA_anti-like DUF4211 PF13926.6 OAG39828.1 - 0.067 13.2 0.1 0.12 12.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4211) Dimerisation PF08100.11 OAG39828.1 - 0.15 12.1 0.0 10 6.3 0.0 2.6 2 0 0 2 2 2 0 Dimerisation domain Mito_carr PF00153.27 OAG39829.1 - 4.3e-75 247.7 3.3 1.7e-24 85.5 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 OAG39829.1 - 0.00022 20.5 0.7 0.02 14.0 0.0 3.0 3 1 1 4 4 4 2 Gammaproteobacterial serine protease RRM_1 PF00076.22 OAG39830.1 - 1.1e-12 47.6 0.0 1.5e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 OAG39830.1 - 0.00015 21.7 0.0 0.00021 21.2 0.0 1.2 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif EIF4E-T PF10477.9 OAG39830.1 - 4.7 5.9 26.3 5.7 5.6 26.3 1.0 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E NOA36 PF06524.12 OAG39830.1 - 8.8 5.6 12.0 12 5.1 12.0 1.3 1 0 0 1 1 1 0 NOA36 protein PALP PF00291.25 OAG39831.1 - 5.7e-64 216.3 0.1 7.7e-64 215.9 0.1 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.28 OAG39831.1 - 1e-11 45.1 0.0 4.1e-08 33.5 0.0 2.9 2 0 0 2 2 2 2 CBS domain adh_short PF00106.25 OAG39832.1 - 5e-15 55.5 0.0 6.8e-15 55.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG39832.1 - 9.2e-12 45.0 0.1 1.6e-11 44.2 0.1 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Glyco_tran_WecB PF03808.13 OAG39832.1 - 0.00018 21.5 0.0 0.02 14.8 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase WecB/TagA/CpsF family Fungal_trans PF04082.18 OAG39833.1 - 1.4e-08 34.1 0.5 2.7e-08 33.2 0.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Dioxygenase_C PF00775.21 OAG39834.1 - 9.6e-42 142.5 0.0 1.2e-41 142.1 0.0 1.1 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 OAG39834.1 - 4.7e-22 77.6 0.1 7e-22 77.1 0.1 1.2 1 0 0 1 1 1 1 Catechol dioxygenase N terminus Abhydrolase_6 PF12697.7 OAG39835.1 - 6.6e-17 62.9 0.0 7.9e-17 62.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG39835.1 - 0.022 14.0 0.0 0.34 10.1 0.0 2.1 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OAG39835.1 - 0.07 12.8 0.0 0.15 11.7 0.0 1.5 2 0 0 2 2 2 0 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 OAG39835.1 - 0.13 11.1 0.0 0.2 10.5 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme PGAP1 PF07819.13 OAG39835.1 - 0.13 12.0 0.1 0.19 11.4 0.1 1.3 1 0 0 1 1 1 0 PGAP1-like protein FAD_binding_3 PF01494.19 OAG39836.1 - 3.2e-16 59.5 0.0 5.3e-16 58.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 OAG39836.1 - 7.7e-06 26.0 0.0 1.9e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAG39836.1 - 0.00033 20.3 0.0 0.0053 16.4 0.0 2.1 1 1 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 OAG39836.1 - 0.0027 16.5 0.0 0.016 13.9 0.0 2.0 1 1 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.6 OAG39836.1 - 0.0042 16.4 0.0 0.015 14.6 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAG39836.1 - 0.0089 16.6 0.0 0.089 13.4 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAG39836.1 - 0.02 14.0 0.0 0.099 11.7 0.0 1.9 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_2 PF07992.14 OAG39836.1 - 0.027 13.7 0.0 0.057 12.6 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG39836.1 - 0.05 12.8 0.0 0.15 11.2 0.0 1.7 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 OAG39836.1 - 0.067 12.4 0.0 0.14 11.4 0.0 1.5 1 0 0 1 1 1 0 Thi4 family ApbA PF02558.16 OAG39836.1 - 0.1 12.3 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA adh_short PF00106.25 OAG39837.1 - 1.3e-35 122.6 0.0 1.9e-35 122.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG39837.1 - 6.5e-26 91.3 0.1 1e-25 90.7 0.1 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG39837.1 - 0.00041 20.3 0.7 0.021 14.8 0.0 2.3 2 0 0 2 2 2 2 KR domain Podoplanin PF05808.11 OAG39838.1 - 0.00092 19.4 1.5 0.00092 19.4 1.5 1.8 2 0 0 2 2 2 1 Podoplanin Rax2 PF12768.7 OAG39838.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Mucin PF01456.17 OAG39838.1 - 2 8.4 26.2 0.063 13.3 10.9 2.5 2 0 0 2 2 2 0 Mucin-like glycoprotein RAP1 PF07218.11 OAG39838.1 - 5.6 5.1 4.4 9.3 4.4 4.4 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) FAD_binding_4 PF01565.23 OAG39840.1 - 6.1e-19 68.1 0.0 1.2e-18 67.2 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain DJ-1_PfpI PF01965.24 OAG39841.1 - 1.1e-09 38.4 0.0 1.4e-09 38.0 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family TRI12 PF06609.13 OAG39842.1 - 1.5e-29 102.9 25.7 2.1e-29 102.4 25.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG39842.1 - 5.1e-18 65.1 55.7 5.1e-18 65.1 55.7 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF2417 PF10329.9 OAG39842.1 - 0.013 14.9 2.0 0.029 13.8 2.0 1.5 1 0 0 1 1 1 0 Region of unknown function (DUF2417) Podoplanin PF05808.11 OAG39842.1 - 0.21 11.7 0.0 0.21 11.7 0.0 2.7 4 0 0 4 4 4 0 Podoplanin Glyco_transf_24 PF18404.1 OAG39843.1 - 8.8e-149 494.2 3.0 9.7e-149 494.1 2.0 1.6 2 0 0 2 2 2 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 OAG39843.1 - 2.8e-65 220.8 0.0 4.3e-63 213.6 0.0 2.6 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_15 PF18403.1 OAG39843.1 - 4.9e-52 176.9 0.0 9.7e-49 166.2 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_12 PF18400.1 OAG39843.1 - 5.4e-46 156.9 0.0 9.6e-46 156.1 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_13 PF18401.1 OAG39843.1 - 1.3e-44 151.4 3.6 1.1e-41 142.0 0.3 3.6 4 0 0 4 4 4 2 Thioredoxin-like domain UDP-g_GGTase PF06427.11 OAG39843.1 - 1.2e-43 147.7 0.0 2.3e-43 146.8 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.20 OAG39843.1 - 0.0012 18.5 0.0 0.0022 17.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 8 DUF1416 PF07210.12 OAG39843.1 - 0.13 12.2 0.0 0.36 10.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1416) Rnk_N PF14760.6 OAG39843.1 - 0.16 12.5 1.3 0.53 10.8 0.1 2.7 2 0 0 2 2 2 0 Rnk N-terminus Erythro_esteras PF05139.14 OAG39845.1 - 5.7e-119 398.0 4.5 7.1e-119 397.6 4.5 1.1 1 0 0 1 1 1 1 Erythromycin esterase Myb_DNA-binding PF00249.31 OAG39846.1 - 5.3e-18 64.9 9.3 3.1e-09 36.9 2.9 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OAG39846.1 - 8.2e-12 45.2 8.3 4.3e-09 36.5 1.8 2.9 2 0 0 2 2 2 2 Myb-like DNA-binding domain zf-C2H2_4 PF13894.6 OAG39846.1 - 4.8e-06 27.0 16.0 0.0056 17.4 0.8 4.5 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2 PF00096.26 OAG39846.1 - 2.5e-05 24.5 17.8 0.0067 16.8 0.9 4.5 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 OAG39846.1 - 0.0019 18.5 9.7 0.029 14.7 0.3 3.4 2 1 1 3 3 3 1 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 OAG39846.1 - 0.0065 16.8 2.7 2.5 8.6 0.0 3.1 3 0 0 3 3 3 2 Zinc-finger of C2H2 type DUF4264 PF14084.6 OAG39846.1 - 0.04 13.5 0.0 0.086 12.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4264) zf-C2H2_6 PF13912.6 OAG39846.1 - 0.056 13.5 9.6 2.1 8.4 0.2 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2HE PF16278.5 OAG39846.1 - 0.058 13.9 3.2 4.6 7.8 0.6 3.3 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger LIM PF00412.22 OAG39846.1 - 0.16 12.3 10.6 1.8 8.8 0.9 2.5 2 0 0 2 2 2 0 LIM domain zf-C2H2_8 PF15909.5 OAG39846.1 - 0.69 10.3 3.7 4.3 7.7 0.2 2.6 2 0 0 2 2 2 0 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 OAG39846.1 - 1.1 9.7 9.9 0.27 11.6 0.2 3.5 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding Vma12 PF11712.8 OAG39847.1 - 2.1e-40 138.0 0.0 2.7e-40 137.6 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase ATP-synt_I PF03899.15 OAG39847.1 - 0.0077 16.6 0.2 0.013 15.8 0.2 1.3 1 0 0 1 1 1 1 ATP synthase I chain DUF460 PF04312.13 OAG39847.1 - 0.02 14.6 0.2 0.034 13.8 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF460) Amidohydro_1 PF01979.20 OAG39848.1 - 2.3e-26 92.9 0.0 2.5e-25 89.5 0.0 2.2 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 OAG39848.1 - 1.9e-11 44.2 0.1 1.1e-06 28.5 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family FMO-like PF00743.19 OAG39849.1 - 1.1e-15 57.1 0.0 5.9e-15 54.7 0.0 1.8 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 OAG39849.1 - 2.6e-13 49.9 0.0 4.4e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 OAG39849.1 - 5.6e-12 45.5 0.0 2.4e-11 43.5 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAG39849.1 - 2.1e-09 37.1 0.0 6.2e-07 28.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DUF4863 PF16155.5 OAG39850.1 - 1.2e-68 229.8 0.0 1.4e-68 229.6 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4863) p450 PF00067.22 OAG39851.1 - 1.4e-75 254.8 0.0 2e-75 254.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Acetyltransf_1 PF00583.25 OAG39851.1 - 1.7e-07 31.5 0.0 3.6e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OAG39851.1 - 0.00016 21.6 0.0 0.0003 20.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OAG39851.1 - 0.0014 19.1 0.0 0.0033 17.8 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 OAG39851.1 - 0.02 15.0 1.1 0.093 12.8 0.0 2.7 3 1 0 3 3 3 0 Acetyltransferase (GNAT) domain Sugar_tr PF00083.24 OAG39852.1 - 4.8e-81 272.9 17.4 6.7e-81 272.4 17.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG39852.1 - 1.5e-21 76.7 30.4 5.8e-21 74.8 24.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Lactamase_B PF00753.27 OAG39853.1 - 9.8e-12 45.3 0.4 1.6e-11 44.6 0.4 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OAG39853.1 - 0.08 12.4 0.0 0.15 11.5 0.0 1.6 1 0 0 1 1 1 0 Beta-lactamase superfamily domain adh_short_C2 PF13561.6 OAG39854.1 - 3.2e-30 105.4 0.0 4.2e-30 105.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG39854.1 - 4e-22 78.6 0.0 5.1e-22 78.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG39854.1 - 6.6e-09 35.9 0.0 1.1e-08 35.3 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OAG39854.1 - 0.01 15.0 0.1 0.014 14.6 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein adh_short PF00106.25 OAG39855.1 - 1.4e-33 116.0 0.0 1.9e-33 115.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG39855.1 - 1.2e-25 90.5 0.0 2.3e-25 89.5 0.0 1.4 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Pyr_redox_2 PF07992.14 OAG39856.1 - 3.6e-10 39.6 0.0 3.7e-06 26.4 0.0 2.6 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG39856.1 - 2.2e-09 37.4 0.0 6.8e-09 35.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.19 OAG39856.1 - 1.7e-08 33.3 0.0 1.5e-07 30.3 0.0 2.3 2 1 1 3 3 3 1 Flavin-binding monooxygenase-like DAO PF01266.24 OAG39856.1 - 1.4e-06 28.2 0.0 0.033 13.8 0.0 3.4 1 1 2 3 3 3 3 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 OAG39856.1 - 1.5e-06 27.7 0.0 7.7e-05 22.1 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG39856.1 - 0.00019 20.7 0.0 0.057 12.6 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 OAG39856.1 - 0.0024 17.9 0.1 0.16 12.0 0.0 2.9 3 0 0 3 3 3 1 FAD-NAD(P)-binding CoA_binding PF02629.19 OAG39856.1 - 0.0068 17.1 0.0 0.47 11.2 0.0 2.6 2 0 0 2 2 2 1 CoA binding domain HI0933_like PF03486.14 OAG39856.1 - 0.044 12.5 0.0 0.54 8.9 0.1 2.2 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox PF00070.27 OAG39856.1 - 0.073 13.6 0.4 7.8 7.1 0.0 3.4 4 0 0 4 4 4 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAG39856.1 - 0.12 11.6 0.1 1.6 7.9 0.0 2.4 3 0 0 3 3 3 0 Thi4 family NAD_binding_8 PF13450.6 OAG39857.1 - 3.3e-11 43.3 0.0 1e-10 41.7 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.19 OAG39857.1 - 9.5e-09 34.2 0.1 8.4e-08 31.1 0.0 2.1 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 OAG39857.1 - 3.1e-06 26.6 0.0 0.012 14.9 0.0 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG39857.1 - 4.6e-06 26.0 0.0 0.21 10.7 0.0 3.3 3 1 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 OAG39857.1 - 1.5e-05 24.7 0.0 0.00091 18.9 0.0 3.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 OAG39857.1 - 0.00047 20.2 0.0 0.0019 18.2 0.0 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 OAG39857.1 - 0.043 13.1 0.0 1.3 8.2 0.0 2.8 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAG39857.1 - 0.27 10.5 0.0 0.72 9.0 0.0 1.6 2 0 0 2 2 2 0 Thi4 family S_locus_glycop PF00954.20 OAG39857.1 - 9.3 6.8 7.4 4.4 7.9 0.7 2.8 3 0 0 3 3 3 0 S-locus glycoprotein domain adh_short_C2 PF13561.6 OAG39858.1 - 3.6e-59 200.2 0.0 5.4e-59 199.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG39858.1 - 7.5e-47 159.3 0.0 1.1e-46 158.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG39858.1 - 2.2e-09 37.5 0.0 4.4e-09 36.5 0.0 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG39858.1 - 0.0018 17.8 0.0 0.004 16.7 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 OAG39859.1 - 9.6e-30 103.5 0.0 1.8e-29 102.6 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG39859.1 - 4e-21 75.6 0.0 1.1e-20 74.3 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG39859.1 - 0.0045 16.9 0.0 0.14 12.1 0.0 2.5 3 0 0 3 3 3 1 KR domain Methyltransf_23 PF13489.6 OAG39859.1 - 0.077 12.8 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Aldedh PF00171.22 OAG39860.1 - 1.3e-161 538.2 0.0 1.5e-161 538.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 OAG39860.1 - 0.014 14.8 0.0 1.5 8.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) TPR_10 PF13374.6 OAG39860.1 - 0.078 12.9 0.1 2.2 8.2 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Fungal_trans PF04082.18 OAG39861.1 - 1.3e-15 57.1 0.3 2.6e-15 56.2 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Mn_catalase PF05067.12 OAG39861.1 - 0.056 12.4 0.0 0.093 11.7 0.0 1.2 1 0 0 1 1 1 0 Manganese containing catalase ADH_zinc_N PF00107.26 OAG39862.1 - 7.9e-27 93.8 0.3 1.4e-26 93.0 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAG39862.1 - 8e-22 78.7 0.1 1.5e-21 77.8 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG39862.1 - 1.2e-06 28.4 0.0 4.5e-06 26.5 0.0 2.0 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ELFV_dehydrog PF00208.21 OAG39862.1 - 0.016 14.9 0.0 0.03 14.1 0.0 1.4 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Sugar_tr PF00083.24 OAG39863.1 - 4.3e-82 276.4 24.7 5.3e-82 276.1 24.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG39863.1 - 8.4e-22 77.6 37.3 1.1e-19 70.6 24.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily FAA_hydrolase PF01557.18 OAG39864.1 - 6.1e-08 32.6 0.0 1.1e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family SURF6 PF04935.12 OAG39865.1 - 5.7e-47 160.1 37.6 5.7e-47 160.1 37.6 3.9 3 2 0 3 3 3 1 Surfeit locus protein 6 RRP14 PF15459.6 OAG39865.1 - 2.6e-17 63.2 1.5 2.6e-17 63.2 1.5 7.6 5 2 1 6 6 6 1 60S ribosome biogenesis protein Rrp14 LysM PF01476.20 OAG39866.1 - 2.8e-09 36.9 0.5 1.7e-07 31.2 0.0 3.4 4 0 0 4 4 4 1 LysM domain TonB_C PF03544.14 OAG39866.1 - 0.0028 18.0 0.0 0.0057 17.1 0.0 1.5 1 0 0 1 1 1 1 Gram-negative bacterial TonB protein C-terminal Lysozyme_like PF13702.6 OAG39866.1 - 0.15 11.8 0.4 0.32 10.7 0.4 1.6 1 1 0 1 1 1 0 Lysozyme-like Lactamase_B PF00753.27 OAG39867.1 - 6e-17 62.3 4.4 3.3e-16 59.9 4.4 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OAG39867.1 - 4.9e-07 29.5 0.2 7.8e-07 28.8 0.2 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 OAG39867.1 - 0.055 13.4 0.0 0.086 12.7 0.0 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Pyr_redox_2 PF07992.14 OAG39868.1 - 2.2e-13 50.1 0.0 9.8e-08 31.6 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAG39868.1 - 0.0062 16.2 0.2 0.013 15.1 0.2 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 OAG39868.1 - 0.016 15.2 0.0 0.084 12.9 0.0 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 OAG39868.1 - 0.034 13.4 0.0 6.4 5.9 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OAG39868.1 - 0.12 11.4 0.0 0.21 10.6 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein MFS_1 PF07690.16 OAG39869.1 - 2.8e-32 112.0 37.7 2.8e-32 112.0 37.7 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily PsbN PF02468.15 OAG39869.1 - 3.2 7.7 8.6 19 5.2 0.7 3.9 3 0 0 3 3 3 0 Photosystem II reaction centre N protein (psbN) cNMP_binding PF00027.29 OAG39870.1 - 3.1e-40 136.1 0.0 6e-21 74.3 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.17 OAG39870.1 - 4.2e-06 26.3 0.2 7.5e-06 25.5 0.2 1.4 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit AMPK1_CBM PF16561.5 OAG39871.1 - 5.3e-18 65.0 0.2 9.7e-18 64.2 0.2 1.3 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase CBM_48 PF02922.18 OAG39871.1 - 0.0024 18.2 0.1 0.0059 16.9 0.1 1.6 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Thioredoxin_6 PF13848.6 OAG39872.1 - 6.6e-19 68.5 0.0 1.1e-18 67.8 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin PF00085.20 OAG39872.1 - 6.4e-08 32.5 0.2 0.00093 19.2 0.1 2.4 2 0 0 2 2 2 2 Thioredoxin 2OG-FeII_Oxy_3 PF13640.6 OAG39873.1 - 4.7e-09 37.0 0.0 8.7e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily eRF1_1 PF03463.15 OAG39874.1 - 1.7e-48 163.9 0.0 2.7e-48 163.2 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.15 OAG39874.1 - 2.9e-20 72.9 0.0 4.6e-20 72.3 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 OAG39874.1 - 1.6e-19 70.5 0.0 2.7e-19 69.7 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 3 MFS_1 PF07690.16 OAG39876.1 - 2.8e-38 131.8 36.2 2.8e-38 131.8 36.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PKD PF00801.20 OAG39876.1 - 0.041 13.7 0.6 0.099 12.5 0.6 1.5 1 0 0 1 1 1 0 PKD domain GPR_Gpa2_C PF11970.8 OAG39876.1 - 0.48 10.5 2.9 7.9 6.6 0.5 3.1 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 C-term NPR2 PF06218.11 OAG39877.1 - 6.2e-128 427.3 0.0 4.2e-127 424.6 0.0 1.9 1 1 0 1 1 1 1 Nitrogen permease regulator 2 MFS_1 PF07690.16 OAG39878.1 - 3.9e-25 88.5 29.7 3.9e-25 88.5 29.7 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Amidase PF01425.21 OAG39879.1 - 2.8e-81 273.8 0.0 8.1e-81 272.3 0.0 1.7 1 1 0 1 1 1 1 Amidase PALP PF00291.25 OAG39880.1 - 1.1e-60 205.5 0.1 2.4e-60 204.5 0.1 1.5 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme IlvN PF07991.12 OAG39881.1 - 6.3e-47 159.2 0.0 9.8e-47 158.6 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 OAG39881.1 - 9.1e-40 136.3 0.0 1.4e-39 135.7 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.17 OAG39881.1 - 0.033 14.8 0.1 0.11 13.1 0.0 1.9 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Pyr_redox_2 PF07992.14 OAG39882.1 - 8.3e-14 51.5 0.0 1.7e-10 40.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 OAG39882.1 - 8.2e-12 44.3 0.1 3.1e-11 42.4 0.0 1.8 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OAG39882.1 - 3.3e-08 33.6 0.0 6.7e-05 23.0 0.0 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 OAG39882.1 - 1.2e-07 31.3 0.0 0.00066 19.0 0.0 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OAG39882.1 - 0.00017 20.8 0.0 0.023 13.7 0.0 3.2 2 1 0 2 2 2 1 Lycopene cyclase protein Pyr_redox PF00070.27 OAG39882.1 - 0.00042 20.8 0.1 0.35 11.4 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG39882.1 - 0.00043 19.5 0.0 0.02 14.0 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 OAG39882.1 - 0.0028 17.7 0.1 0.16 12.0 0.0 3.0 3 0 0 3 3 3 1 FAD-NAD(P)-binding Shikimate_DH PF01488.20 OAG39882.1 - 0.015 15.3 0.1 1.6 8.8 0.0 2.5 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.17 OAG39882.1 - 0.04 13.1 0.5 0.66 9.2 0.0 2.5 3 0 0 3 3 3 0 Thi4 family EcKinase PF02958.20 OAG39883.1 - 1.7e-17 63.7 0.0 4.8e-16 58.9 0.0 2.2 1 1 0 1 1 1 1 Ecdysteroid kinase APH PF01636.23 OAG39883.1 - 1.8e-12 47.7 4.1 3e-12 47.0 4.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 OAG39883.1 - 0.033 13.1 0.0 0.052 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) ABC2_membrane PF01061.24 OAG39884.1 - 3.7e-90 301.0 51.3 3.5e-48 163.8 22.3 2.8 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 OAG39884.1 - 2.5e-40 138.2 0.0 2.8e-17 63.5 0.0 3.8 4 0 0 4 4 4 3 ABC transporter PDR_CDR PF06422.12 OAG39884.1 - 2.2e-34 117.2 12.1 1.6e-32 111.2 0.0 3.7 4 0 0 4 4 2 2 CDR ABC transporter ABC_trans_N PF14510.6 OAG39884.1 - 5.3e-17 62.2 5.8 1.2e-16 61.1 4.6 2.3 2 1 0 2 2 1 1 ABC-transporter N-terminal AAA_33 PF13671.6 OAG39884.1 - 1.5e-07 31.7 0.0 0.028 14.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 OAG39884.1 - 9.7e-07 29.3 0.1 0.0095 16.3 0.1 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 OAG39884.1 - 2.8e-06 27.3 0.0 0.16 11.7 0.0 3.4 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 OAG39884.1 - 5.8e-06 25.7 17.6 5.8e-06 25.7 17.6 2.9 2 1 1 3 3 3 1 ABC-2 family transporter protein AAA_18 PF13238.6 OAG39884.1 - 6e-06 26.8 0.0 0.014 15.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 OAG39884.1 - 1.4e-05 24.7 0.1 0.00033 20.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 OAG39884.1 - 1.8e-05 24.7 0.1 0.0018 18.2 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 OAG39884.1 - 0.00041 20.0 1.4 0.032 14.0 0.1 2.7 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_17 PF13207.6 OAG39884.1 - 0.0012 19.3 0.1 0.22 11.9 0.0 2.8 3 0 0 3 3 2 1 AAA domain SMC_N PF02463.19 OAG39884.1 - 0.0031 17.0 0.0 0.41 10.1 0.0 3.3 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 OAG39884.1 - 0.0047 16.7 0.2 0.24 11.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 OAG39884.1 - 0.0061 16.8 0.2 3.2 8.0 0.1 2.6 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 OAG39884.1 - 0.022 14.5 0.1 3.6 7.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 OAG39884.1 - 0.028 14.0 0.6 0.58 9.7 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.6 OAG39884.1 - 0.029 14.6 0.0 5 7.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 OAG39884.1 - 0.032 14.1 0.5 3.2 7.6 0.3 2.7 2 0 0 2 2 2 0 NACHT domain Rad17 PF03215.15 OAG39884.1 - 0.057 13.3 0.0 2.5 8.0 0.0 2.2 2 0 0 2 2 2 0 Rad17 P-loop domain AAA PF00004.29 OAG39884.1 - 0.16 12.4 0.0 23 5.4 0.0 2.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) BTB PF00651.31 OAG39885.1 - 0.00099 19.3 0.0 0.0022 18.2 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain NAD_binding_4 PF07993.12 OAG39886.1 - 0.001 18.3 0.0 0.018 14.2 0.0 2.0 2 0 0 2 2 2 1 Male sterility protein Epimerase PF01370.21 OAG39886.1 - 0.0012 18.3 0.0 0.0017 17.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.20 OAG39886.1 - 0.0029 17.7 0.1 0.0088 16.2 0.1 1.9 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus NAD_binding_10 PF13460.6 OAG39886.1 - 0.0063 16.4 0.0 0.031 14.2 0.0 1.9 2 0 0 2 2 2 1 NAD(P)H-binding 3Beta_HSD PF01073.19 OAG39886.1 - 0.047 12.7 0.0 0.073 12.1 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 OAG39886.1 - 0.048 12.8 0.1 0.089 11.9 0.1 1.5 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 OAG39886.1 - 0.2 10.7 0.0 0.27 10.3 0.0 1.1 1 0 0 1 1 1 0 RmlD substrate binding domain Chitin_synth_1 PF01644.17 OAG39887.1 - 4.1e-70 235.0 0.0 6.8e-70 234.3 0.0 1.4 1 0 0 1 1 1 1 Chitin synthase UQ_con PF00179.26 OAG39887.1 - 1.2e-36 125.4 0.0 2.1e-36 124.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Chitin_synth_1N PF08407.11 OAG39887.1 - 2.2e-28 98.0 0.0 4.2e-28 97.1 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 OAG39887.1 - 4.5e-23 81.7 4.7 3.3e-18 65.6 0.0 2.5 3 0 0 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.6 OAG39887.1 - 3.6e-07 30.3 0.8 3.6e-07 30.3 0.8 2.1 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 OAG39887.1 - 0.095 12.6 0.0 0.95 9.3 0.0 2.4 2 0 0 2 2 2 0 Glycosyltransferase like family 2 DNA_primase_S PF01896.19 OAG39889.1 - 2.5e-58 197.0 0.1 4.4e-58 196.2 0.1 1.4 2 0 0 2 2 2 1 DNA primase small subunit HHV6-IE PF03753.13 OAG39889.1 - 0.16 9.4 0.0 0.24 8.8 0.0 1.2 1 0 0 1 1 1 0 Human herpesvirus 6 immediate early protein Amidohydro_2 PF04909.14 OAG39890.1 - 3.5e-42 145.2 0.2 3.9e-42 145.0 0.2 1.1 1 0 0 1 1 1 1 Amidohydrolase RPEL PF02755.15 OAG39890.1 - 0.065 12.9 0.3 0.13 12.0 0.3 1.5 1 0 0 1 1 1 0 RPEL repeat Fungal_trans PF04082.18 OAG39891.1 - 1.1e-28 100.0 0.0 1.4e-17 63.7 0.0 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG39891.1 - 4.9e-08 33.0 7.6 8e-08 32.3 7.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short_C2 PF13561.6 OAG39892.1 - 2.9e-55 187.4 0.2 3.4e-55 187.1 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG39892.1 - 1.1e-42 145.8 0.6 1.6e-42 145.2 0.6 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG39892.1 - 1.3e-11 44.8 0.4 1.9e-11 44.2 0.4 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG39892.1 - 0.011 15.2 0.0 0.017 14.6 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Sugar_tr PF00083.24 OAG39893.1 - 2.3e-87 293.8 24.0 2.6e-87 293.6 24.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG39893.1 - 8.9e-11 41.3 52.2 1.3e-06 27.6 18.1 2.3 1 1 0 2 2 2 2 Major Facilitator Superfamily SLT PF01464.20 OAG39894.1 - 0.0013 18.3 0.0 1.6 8.4 0.0 2.2 1 1 1 2 2 2 2 Transglycosylase SLT domain SLT_2 PF13406.6 OAG39894.1 - 0.078 12.2 0.0 0.12 11.6 0.0 1.1 1 0 0 1 1 1 0 Transglycosylase SLT domain Sugar_tr PF00083.24 OAG39895.1 - 1.1e-84 284.9 23.3 1.3e-84 284.7 23.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG39895.1 - 4.7e-18 65.2 32.5 3.3e-16 59.2 27.3 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Zn_clus PF00172.18 OAG39896.1 - 1.2e-08 34.9 9.6 2.1e-08 34.1 9.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAG39896.1 - 0.0015 17.6 1.6 0.055 12.5 0.4 2.7 2 1 0 2 2 2 1 Fungal specific transcription factor domain SnoaL_2 PF12680.7 OAG39897.1 - 0.00074 20.1 0.0 0.0017 19.0 0.0 1.6 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 OAG39897.1 - 0.0027 17.5 0.0 0.0055 16.5 0.0 1.5 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase DEAD PF00270.29 OAG39898.1 - 1.4e-44 152.0 0.0 2.4e-44 151.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAG39898.1 - 9.1e-24 83.9 0.0 3.7e-23 82.0 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 OAG39898.1 - 1.2e-19 70.2 0.1 2.2e-19 69.4 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 OAG39898.1 - 8.5e-05 22.6 0.0 0.00017 21.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF4778 PF16008.5 OAG39898.1 - 0.11 12.6 3.7 0.16 12.0 3.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) AAA_22 PF13401.6 OAG39898.1 - 0.13 12.5 0.2 0.64 10.3 0.0 2.2 3 0 0 3 3 3 0 AAA domain TIMELESS_C PF05029.13 OAG39898.1 - 0.13 11.4 13.1 0.21 10.7 13.1 1.2 1 0 0 1 1 1 0 Timeless protein C terminal region Pro-kuma_activ PF09286.11 OAG39899.1 - 1.4e-36 125.9 0.0 3e-36 124.8 0.0 1.6 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Pkinase PF00069.25 OAG39900.1 - 6.2e-68 229.0 0.0 7.8e-68 228.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG39900.1 - 4.2e-32 111.4 0.0 5.9e-32 111.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OAG39900.1 - 0.0057 15.6 0.0 0.02 13.9 0.0 1.9 2 1 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 OAG39900.1 - 0.035 13.4 0.0 0.068 12.5 0.0 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OAG39900.1 - 0.045 13.7 0.6 0.16 11.9 0.0 2.1 3 0 0 3 3 3 0 Phosphotransferase enzyme family OTU PF02338.19 OAG39901.1 - 1.2e-21 77.6 1.6 1.9e-21 76.9 0.0 2.1 3 0 0 3 3 3 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 OAG39901.1 - 0.0037 16.7 2.0 1.7 8.0 0.0 2.8 2 1 1 3 3 3 2 Peptidase C65 Otubain PASTA PF03793.19 OAG39901.1 - 0.06 13.2 0.2 14 5.7 0.0 2.6 2 0 0 2 2 2 0 PASTA domain DUF445 PF04286.12 OAG39901.1 - 0.063 13.1 2.7 0.077 12.8 2.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Peptidase_C78 PF07910.13 OAG39901.1 - 0.11 11.9 0.5 0.21 11.1 0.0 1.6 2 0 0 2 2 2 0 Peptidase family C78 DUF3138 PF11336.8 OAG39901.1 - 0.32 9.6 1.1 0.48 9.0 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Rib_recp_KP_reg PF05104.12 OAG39901.1 - 1 10.4 18.8 2.1 9.4 18.8 1.5 1 0 0 1 1 1 0 Ribosome receptor lysine/proline rich region Mitofilin PF09731.9 OAG39901.1 - 3.4 6.4 22.0 2.2 7.0 2.0 2.0 1 1 1 2 2 2 0 Mitochondrial inner membrane protein CEP19 PF14933.6 OAG39901.1 - 5 7.4 8.1 16 5.8 8.1 1.8 1 1 0 1 1 1 0 CEP19-like protein SLX9 PF15341.6 OAG39901.1 - 7.3 7.0 18.1 4.7 7.6 5.9 2.4 1 1 1 2 2 2 0 Ribosome biogenesis protein SLX9 TPMT PF05724.11 OAG39902.1 - 3.1e-29 102.2 0.0 2.9e-28 99.0 0.0 2.2 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_25 PF13649.6 OAG39902.1 - 5.2e-05 23.9 0.0 0.00028 21.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG39902.1 - 0.00049 20.7 0.0 0.0018 18.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAG39902.1 - 0.0015 18.3 0.0 0.002 18.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG39902.1 - 0.0027 17.5 0.1 0.005 16.6 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 OAG39902.1 - 0.049 13.0 0.0 0.08 12.3 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_12 PF08242.12 OAG39902.1 - 0.078 13.7 0.0 0.22 12.3 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain N2227 PF07942.12 OAG39902.1 - 0.14 11.3 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 N2227-like protein MFS_1 PF07690.16 OAG39903.1 - 1.2e-43 149.4 26.7 1.2e-43 149.4 26.7 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG39903.1 - 7.2e-10 38.3 9.9 7.2e-10 38.3 9.9 3.1 2 1 1 3 3 3 2 Sugar (and other) transporter OATP PF03137.20 OAG39903.1 - 0.012 13.9 11.0 0.013 13.8 1.8 3.3 1 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Ribosomal_60s PF00428.19 OAG39904.1 - 0.00027 21.4 26.4 0.01 16.4 10.5 2.3 1 1 1 2 2 2 2 60s Acidic ribosomal protein DUF4707 PF15806.5 OAG39904.1 - 0.35 9.7 1.5 0.39 9.6 1.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4707) Mitofilin PF09731.9 OAG39904.1 - 5.1 5.8 19.7 5.6 5.7 19.7 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein TP53IP5 PF15331.6 OAG39904.1 - 6.7 6.8 10.5 7.7 6.6 10.5 1.1 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 DUF3431 PF11913.8 OAG39905.1 - 2.6e-17 63.3 0.1 3.3e-08 33.6 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3431) CHORD PF04968.12 OAG39906.1 - 6.4e-49 164.5 18.9 8.8e-26 90.4 5.5 2.4 2 0 0 2 2 2 2 CHORD CS PF04969.16 OAG39906.1 - 8.2e-15 55.6 0.0 1.3e-14 55.0 0.0 1.3 1 0 0 1 1 1 1 CS domain DUF5309 PF17236.2 OAG39906.1 - 0.044 13.1 0.0 0.074 12.4 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5309) BTK PF00779.19 OAG39906.1 - 0.2 11.5 14.0 0.18 11.6 0.5 3.2 3 1 0 3 3 3 0 BTK motif SIR2 PF02146.17 OAG39910.1 - 7.8e-29 100.8 0.0 4.2e-28 98.5 0.0 2.0 1 1 0 1 1 1 1 Sir2 family Med16 PF11635.8 OAG39911.1 - 8.3e-54 182.7 0.0 1.3e-53 182.1 0.0 1.3 1 1 0 1 1 1 1 Mediator complex subunit 16 ANAPC4_WD40 PF12894.7 OAG39911.1 - 0.065 13.5 0.0 0.61 10.4 0.0 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Ribosomal_L29 PF00831.23 OAG39912.1 - 5.2e-13 48.8 6.4 6.4e-09 35.6 0.1 2.8 3 0 0 3 3 3 2 Ribosomal L29 protein V-SNARE_C PF12352.8 OAG39913.1 - 1.2e-14 54.3 0.7 1.2e-14 54.3 0.7 2.8 4 0 0 4 4 4 1 Snare region anchored in the vesicle membrane C-terminus GOLGA2L5 PF15070.6 OAG39913.1 - 0.0024 16.6 6.4 0.0033 16.2 6.4 1.3 1 0 0 1 1 1 1 Putative golgin subfamily A member 2-like protein 5 Syntaxin-6_N PF09177.11 OAG39913.1 - 0.0057 17.2 3.2 0.0057 17.2 3.2 2.2 1 1 1 2 2 2 2 Syntaxin 6, N-terminal HTH_20 PF12840.7 OAG39913.1 - 0.07 13.2 1.8 0.15 12.2 0.8 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain FlgT_M PF16539.5 OAG39913.1 - 0.081 13.1 2.4 0.12 12.5 2.1 1.4 1 1 0 1 1 1 0 Flagellar assembly protein T, middle domain Surfac_D-trimer PF09006.11 OAG39913.1 - 0.11 12.4 0.2 0.57 10.1 0.0 2.2 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation STAT_alpha PF01017.20 OAG39913.1 - 0.16 11.9 4.1 0.67 9.8 4.2 2.1 1 1 0 1 1 1 0 STAT protein, all-alpha domain CHAD PF05235.14 OAG39913.1 - 0.22 11.5 8.5 0.032 14.2 2.6 2.1 1 1 1 2 2 2 0 CHAD domain DUF4407 PF14362.6 OAG39913.1 - 0.33 10.3 6.0 1.7 7.9 6.0 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Atg14 PF10186.9 OAG39913.1 - 0.52 9.3 10.6 0.72 8.9 9.6 1.6 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Spc7 PF08317.11 OAG39913.1 - 0.97 8.2 10.1 0.53 9.1 7.9 1.7 2 1 0 2 2 2 0 Spc7 kinetochore protein Sec34 PF04136.15 OAG39913.1 - 1.3 8.9 7.5 2.9 7.7 3.3 2.8 2 1 1 3 3 3 0 Sec34-like family ATP-synt_10 PF05176.14 OAG39914.1 - 3.2e-67 226.5 0.0 4.3e-67 226.1 0.0 1.1 1 0 0 1 1 1 1 ATP10 protein DNA_pol_B_palm PF14792.6 OAG39915.1 - 2.5e-30 105.0 0.0 2.9e-29 101.6 0.0 2.3 2 0 0 2 2 2 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.6 OAG39915.1 - 1.8e-25 88.9 0.8 3.5e-24 84.7 0.2 2.6 2 0 0 2 2 2 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.9 OAG39915.1 - 2.5e-19 68.8 0.3 7.8e-19 67.3 0.1 2.0 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.6 OAG39915.1 - 9.6e-14 51.5 0.2 2.4e-13 50.2 0.2 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain NTP_transf_2 PF01909.23 OAG39915.1 - 0.0007 19.8 0.0 0.0057 16.9 0.0 2.3 2 0 0 2 2 2 1 Nucleotidyltransferase domain F_actin_bind PF08919.10 OAG39915.1 - 0.035 14.2 2.0 0.035 14.2 0.1 2.0 2 0 0 2 2 2 0 F-actin binding BRCT_2 PF16589.5 OAG39915.1 - 0.051 14.0 0.0 0.11 13.0 0.0 1.5 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain zf-BED PF02892.15 OAG39916.1 - 0.0023 17.9 0.6 0.008 16.2 0.6 1.9 1 0 0 1 1 1 1 BED zinc finger Zn_clus PF00172.18 OAG39916.1 - 0.0028 17.8 4.7 0.0028 17.8 4.7 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CRC_subunit PF08624.10 OAG39917.1 - 1.4e-51 174.4 0.2 2e-51 174.0 0.2 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit AT_hook PF02178.19 OAG39917.1 - 2 8.6 6.4 6.8 6.9 6.4 2.0 1 0 0 1 1 1 0 AT hook motif FAD_binding_3 PF01494.19 OAG39918.1 - 4e-19 69.1 0.1 8.9e-19 67.9 0.1 1.5 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 OAG39918.1 - 5.4e-05 22.6 0.6 0.11 11.8 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAG39918.1 - 0.00089 18.6 0.3 0.01 15.1 0.1 2.1 2 0 0 2 2 2 1 Thi4 family Amino_oxidase PF01593.24 OAG39918.1 - 0.0016 17.8 0.2 1.2 8.4 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 OAG39918.1 - 0.0022 17.1 2.5 0.071 12.2 0.5 2.4 1 1 1 2 2 2 2 FAD binding domain DAO PF01266.24 OAG39918.1 - 0.0032 17.1 2.5 0.19 11.3 0.0 2.3 2 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAG39918.1 - 0.015 15.6 0.1 0.035 14.3 0.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 OAG39918.1 - 0.11 11.5 0.5 0.18 10.8 0.0 1.5 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox PF00070.27 OAG39918.1 - 0.18 12.4 0.1 3.8 8.1 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAG39918.1 - 0.2 10.3 0.6 2.6 6.6 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein MFS_1 PF07690.16 OAG39919.1 - 9.1e-29 100.5 25.8 9.1e-29 100.5 25.8 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 OAG39919.1 - 0.00017 20.2 1.2 0.00027 19.5 1.2 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) FAM70 PF14967.6 OAG39919.1 - 0.029 13.9 1.8 0.045 13.2 1.0 1.6 2 0 0 2 2 2 0 FAM70 protein Bromo_coat PF01318.18 OAG39920.1 - 0.16 12.0 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 Bromovirus coat protein Fungal_trans PF04082.18 OAG39921.1 - 3.4e-08 32.9 0.7 1.5e-06 27.4 0.7 2.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain SLD3 PF08639.10 OAG39922.1 - 5e-129 431.5 15.6 5e-129 431.5 15.6 1.8 2 0 0 2 2 2 1 DNA replication regulator SLD3 Syntaxin_2 PF14523.6 OAG39923.1 - 1.2e-21 77.0 3.8 2.6e-20 72.7 0.6 2.4 2 0 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.19 OAG39923.1 - 2.5e-16 59.4 1.3 6.1e-16 58.2 1.3 1.7 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 OAG39923.1 - 0.00077 19.2 10.2 0.011 15.5 10.0 2.4 1 1 0 1 1 1 1 Syntaxin Prominin PF05478.11 OAG39923.1 - 0.005 14.9 0.7 0.0081 14.2 0.1 1.5 2 0 0 2 2 2 1 Prominin Nitr_red_assoc PF09655.10 OAG39923.1 - 0.035 14.7 0.1 0.065 13.9 0.1 1.4 1 0 0 1 1 1 0 Conserved nitrate reductase-associated protein (Nitr_red_assoc) DUF883 PF05957.13 OAG39923.1 - 0.14 12.8 4.4 0.41 11.3 0.0 2.8 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) PMC2NT PF08066.12 OAG39923.1 - 0.15 12.8 1.4 0.28 11.9 0.1 2.0 2 0 0 2 2 2 0 PMC2NT (NUC016) domain Ndc1_Nup PF09531.10 OAG39924.1 - 4.5e-144 481.5 0.3 4.5e-144 481.5 0.3 1.5 1 1 1 2 2 2 1 Nucleoporin protein Ndc1-Nup IKI3 PF04762.12 OAG39925.1 - 2.8e-273 909.3 0.0 3.5e-273 909.0 0.0 1.1 1 0 0 1 1 1 1 IKI3 family ANAPC4_WD40 PF12894.7 OAG39925.1 - 0.0007 19.8 0.1 38 4.7 0.0 4.4 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Baculo_DNA_bind PF04786.12 OAG39925.1 - 0.21 10.9 0.1 0.35 10.2 0.1 1.2 1 0 0 1 1 1 0 ssDNA binding protein AIRS_C PF02769.22 OAG39925.1 - 0.32 11.1 1.0 4.2 7.5 0.1 2.3 2 0 0 2 2 2 0 AIR synthase related protein, C-terminal domain COX7C PF02935.16 OAG39926.1 - 7e-14 51.8 0.5 1.1e-13 51.2 0.5 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc rRNA_proc-arch PF13234.6 OAG39927.1 - 1.2e-87 294.3 0.4 2.6e-87 293.2 0.4 1.6 1 0 0 1 1 1 1 rRNA-processing arch domain Cut8 PF08559.10 OAG39927.1 - 6.2e-78 261.7 0.2 1.2e-77 260.8 0.2 1.5 1 0 0 1 1 1 1 Cut8, nuclear proteasome tether protein DSHCT PF08148.12 OAG39927.1 - 1.7e-52 177.4 1.2 5.3e-52 175.8 1.2 1.9 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.29 OAG39927.1 - 6.4e-18 65.1 0.0 1.7e-17 63.8 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAG39927.1 - 2.6e-06 27.8 0.0 1.3e-05 25.5 0.0 2.2 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG39927.1 - 3.6e-05 23.8 0.0 0.0001 22.4 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ATPase_2 PF01637.18 OAG39927.1 - 0.033 14.1 0.0 0.11 12.3 0.0 1.9 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea T2SSE PF00437.20 OAG39927.1 - 0.051 12.6 0.0 0.11 11.5 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_22 PF13401.6 OAG39927.1 - 0.073 13.3 0.1 0.78 10.0 0.0 2.8 3 0 0 3 3 3 0 AAA domain Cyto_heme_lyase PF01265.17 OAG39928.1 - 7.2e-33 114.4 12.0 1.4e-29 103.6 12.0 3.0 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase MDD_C PF18376.1 OAG39929.1 - 1.1e-63 214.3 0.0 1.7e-63 213.7 0.0 1.3 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 OAG39929.1 - 5.1e-09 36.2 0.8 1.2e-08 35.1 0.8 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain FMO-like PF00743.19 OAG39930.1 - 2.4e-15 55.9 0.1 1.4e-14 53.4 0.1 1.9 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OAG39930.1 - 6.3e-15 55.2 0.0 1.6e-14 53.8 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAG39930.1 - 3.7e-10 39.5 0.0 3.3e-08 33.1 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG39930.1 - 1.9e-09 37.6 0.0 1.8e-07 31.3 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 OAG39930.1 - 1.1e-08 34.6 0.1 5.6e-07 29.0 0.0 2.5 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 OAG39930.1 - 5.7e-08 32.3 0.0 1.1e-06 28.0 0.0 2.2 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 OAG39930.1 - 1.1e-07 31.8 0.9 0.00014 21.6 0.1 3.5 3 1 1 4 4 4 1 FAD dependent oxidoreductase Mqo PF06039.15 OAG39930.1 - 2.5e-05 23.0 0.5 0.0098 14.5 0.1 2.8 3 1 1 4 4 4 2 Malate:quinone oxidoreductase (Mqo) Pyr_redox PF00070.27 OAG39930.1 - 0.00025 21.5 0.1 0.055 14.0 0.0 2.8 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OAG39930.1 - 0.012 14.7 0.0 0.33 10.0 0.0 2.8 3 0 0 3 3 3 0 Lycopene cyclase protein FAD_binding_2 PF00890.24 OAG39930.1 - 0.018 14.1 0.1 0.094 11.8 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain NAD_binding_9 PF13454.6 OAG39930.1 - 0.033 14.2 0.3 22 5.0 0.0 3.3 3 0 0 3 3 3 0 FAD-NAD(P)-binding Shikimate_DH PF01488.20 OAG39930.1 - 0.046 13.8 0.0 0.37 10.9 0.0 2.3 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase YwhD PF08741.10 OAG39930.1 - 0.13 11.9 0.7 0.23 11.2 0.7 1.3 1 0 0 1 1 1 0 YwhD family Aminotran_3 PF00202.21 OAG39931.1 - 2.6e-80 270.1 0.0 3.3e-80 269.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 OAG39931.1 - 0.019 14.2 0.0 0.044 12.9 0.0 1.6 1 0 0 1 1 1 0 Aminotransferase class I and II AAA PF00004.29 OAG39934.1 - 1.7e-85 284.1 0.0 1.5e-41 141.9 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OAG39934.1 - 1.1e-22 79.5 0.4 4e-11 42.5 0.1 3.1 2 0 0 2 2 2 2 AAA+ lid domain RuvB_N PF05496.12 OAG39934.1 - 1.4e-12 47.7 0.0 2.7e-07 30.5 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 OAG39934.1 - 1.2e-11 45.2 1.0 0.00014 22.3 0.4 4.7 2 2 1 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 OAG39934.1 - 1e-10 42.0 0.5 0.0073 16.6 0.0 4.3 2 2 1 3 3 3 2 AAA domain AAA_2 PF07724.14 OAG39934.1 - 8e-10 39.1 0.0 0.00027 21.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 OAG39934.1 - 1.3e-09 38.2 0.2 0.00044 20.3 0.1 3.7 4 1 0 4 4 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 OAG39934.1 - 1.1e-08 35.3 0.0 0.00035 20.7 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_28 PF13521.6 OAG39934.1 - 6.1e-08 33.1 0.0 0.00012 22.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 OAG39934.1 - 6.9e-08 32.9 0.0 0.0012 19.2 0.0 2.9 2 1 0 2 2 2 2 RNA helicase AAA_14 PF13173.6 OAG39934.1 - 9.9e-08 32.1 0.0 0.0013 18.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 OAG39934.1 - 2.7e-07 31.2 0.0 0.00059 20.4 0.0 3.1 2 1 1 3 3 2 1 AAA domain Mg_chelatase PF01078.21 OAG39934.1 - 4.3e-07 29.5 0.1 0.0059 16.0 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 OAG39934.1 - 1.1e-06 28.1 0.0 0.00025 20.3 0.0 2.4 2 0 0 2 2 2 1 TIP49 P-loop domain IstB_IS21 PF01695.17 OAG39934.1 - 1.7e-06 27.9 0.0 0.016 14.9 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_25 PF13481.6 OAG39934.1 - 2.7e-06 27.1 2.4 0.4 10.2 0.0 3.7 2 1 0 3 3 3 2 AAA domain Zeta_toxin PF06414.12 OAG39934.1 - 1e-05 25.0 0.2 0.016 14.5 0.0 3.1 3 0 0 3 3 3 1 Zeta toxin Rad17 PF03215.15 OAG39934.1 - 1.3e-05 25.2 0.0 0.011 15.7 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain Cytidylate_kin2 PF13189.6 OAG39934.1 - 1.6e-05 25.1 0.0 0.00064 19.9 0.0 2.5 2 0 0 2 2 2 1 Cytidylate kinase-like family AAA_3 PF07726.11 OAG39934.1 - 2.9e-05 23.9 0.0 0.018 14.9 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 OAG39934.1 - 3.2e-05 24.5 0.2 0.71 10.4 0.0 3.6 4 0 0 4 4 3 2 ABC transporter TsaE PF02367.17 OAG39934.1 - 3.2e-05 23.9 0.0 0.08 12.9 0.0 2.3 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 OAG39934.1 - 3.6e-05 23.7 0.9 0.1 12.5 0.0 4.0 4 1 1 5 5 4 1 NACHT domain AAA_11 PF13086.6 OAG39934.1 - 0.00019 21.3 0.5 0.67 9.7 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_17 PF13207.6 OAG39934.1 - 0.0002 21.8 0.5 0.058 13.8 0.0 3.1 3 1 0 3 3 2 1 AAA domain ATPase PF06745.13 OAG39934.1 - 0.0002 20.8 0.1 0.19 11.0 0.0 3.1 2 1 1 3 3 3 1 KaiC TniB PF05621.11 OAG39934.1 - 0.00021 20.8 0.0 1.7 8.0 0.0 3.7 2 1 0 3 3 3 1 Bacterial TniB protein AAA_7 PF12775.7 OAG39934.1 - 0.00031 20.3 0.0 0.15 11.6 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region Viral_helicase1 PF01443.18 OAG39934.1 - 0.00032 20.5 0.0 0.49 10.1 0.0 2.3 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase Parvo_NS1 PF01057.17 OAG39934.1 - 0.00051 19.2 0.1 0.29 10.2 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_24 PF13479.6 OAG39934.1 - 0.00067 19.4 0.1 1.4 8.6 0.0 3.0 3 0 0 3 3 3 1 AAA domain SKI PF01202.22 OAG39934.1 - 0.00077 19.6 0.0 0.29 11.3 0.0 2.7 2 0 0 2 2 2 1 Shikimate kinase Sigma54_activat PF00158.26 OAG39934.1 - 0.0012 18.6 0.0 2 8.1 0.0 2.8 2 1 0 2 2 2 1 Sigma-54 interaction domain PhoH PF02562.16 OAG39934.1 - 0.0023 17.4 0.1 2.2 7.7 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein Vps4_C PF09336.10 OAG39934.1 - 0.0027 17.7 0.1 0.87 9.6 0.0 2.9 3 0 0 3 3 2 1 Vps4 C terminal oligomerisation domain DUF815 PF05673.13 OAG39934.1 - 0.0055 15.9 0.0 0.31 10.2 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Sigma54_activ_2 PF14532.6 OAG39934.1 - 0.0069 16.5 0.0 0.43 10.7 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain ATPase_2 PF01637.18 OAG39934.1 - 0.0091 15.9 0.0 11 5.9 0.0 3.3 3 1 1 4 4 3 0 ATPase domain predominantly from Archaea NB-ARC PF00931.22 OAG39934.1 - 0.014 14.6 0.0 2.2 7.4 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain AAA_19 PF13245.6 OAG39934.1 - 0.016 15.6 0.2 2.2 8.6 0.1 2.8 2 1 0 2 2 2 0 AAA domain AFG1_ATPase PF03969.16 OAG39934.1 - 0.026 13.4 0.0 0.32 9.8 0.0 2.4 2 0 0 2 2 2 0 AFG1-like ATPase DUF2075 PF09848.9 OAG39934.1 - 0.032 13.5 0.1 0.99 8.6 0.0 2.5 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Cytidylate_kin PF02224.18 OAG39934.1 - 0.034 13.9 0.3 0.48 10.1 0.1 2.6 2 0 0 2 2 2 0 Cytidylate kinase AAA_30 PF13604.6 OAG39934.1 - 0.039 13.7 0.0 11 5.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain ResIII PF04851.15 OAG39934.1 - 0.057 13.4 0.0 4.5 7.2 0.0 2.7 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit DAP3 PF10236.9 OAG39934.1 - 0.079 12.1 0.0 22 4.1 0.0 3.2 2 1 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 Guanylate_kin PF00625.21 OAG39934.1 - 0.12 12.0 0.7 2.9 7.5 0.0 3.3 3 2 2 5 5 3 0 Guanylate kinase Bac_DnaA PF00308.18 OAG39934.1 - 0.13 12.1 0.0 23 4.7 0.0 2.8 3 1 0 3 3 2 0 Bacterial dnaA protein AAA_23 PF13476.6 OAG39934.1 - 0.22 12.0 3.2 3.2 8.2 0.0 3.0 3 0 0 3 3 3 0 AAA domain Hydin_ADK PF17213.3 OAG39934.1 - 0.36 11.1 0.0 0.36 11.1 0.0 2.7 3 0 0 3 3 3 0 Hydin Adenylate kinase-like domain DUF4260 PF14079.6 OAG39935.1 - 9.3e-41 138.3 0.4 1.1e-40 138.2 0.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4260) Ank_5 PF13857.6 OAG39936.1 - 1.3e-18 66.8 0.0 2.1e-12 47.0 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeats (many copies) VPS9 PF02204.18 OAG39936.1 - 8.8e-16 58.0 0.0 3.6e-15 56.1 0.0 2.1 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ank_2 PF12796.7 OAG39936.1 - 1.3e-12 48.1 0.2 0.00034 21.1 0.1 4.0 2 1 3 5 5 5 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAG39936.1 - 1.3e-07 32.0 0.0 0.042 14.5 0.0 4.7 6 0 0 6 6 6 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG39936.1 - 2.2e-07 30.6 0.4 0.16 12.6 0.0 5.0 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 OAG39936.1 - 1.4e-05 25.3 0.2 0.11 13.0 0.0 4.4 4 0 0 4 4 4 1 Ankyrin repeat PX PF00787.24 OAG39936.1 - 0.00014 21.8 0.3 0.00014 21.8 0.3 2.1 2 0 0 2 2 2 1 PX domain DUF447 PF04289.12 OAG39936.1 - 0.034 13.9 0.0 0.084 12.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF447) Tim44 PF04280.15 OAG39937.1 - 1.2e-34 119.6 0.0 2e-34 118.8 0.0 1.4 1 0 0 1 1 1 1 Tim44-like domain DUF3391 PF11871.8 OAG39937.1 - 0.15 12.6 7.3 0.049 14.2 2.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) Ribosomal_S11 PF00411.19 OAG39938.1 - 9.8e-06 25.9 0.1 0.047 14.1 0.0 2.5 1 1 1 2 2 2 2 Ribosomal protein S11 Sporozoite_P67 PF05642.11 OAG39938.1 - 0.088 10.9 0.3 0.15 10.2 0.2 1.4 2 0 0 2 2 2 0 Sporozoite P67 surface antigen RIC1 PF07064.13 OAG39939.1 - 5.1e-79 265.2 0.0 7.3e-79 264.7 0.0 1.2 1 0 0 1 1 1 1 RIC1 ANAPC4_WD40 PF12894.7 OAG39939.1 - 3.8e-07 30.3 0.0 0.011 16.0 0.0 3.4 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OAG39939.1 - 0.038 14.9 0.7 5.2 8.1 0.1 3.8 3 1 0 3 3 3 0 WD domain, G-beta repeat PD40 PF07676.12 OAG39939.1 - 0.05 13.6 0.3 25 4.9 0.1 3.5 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat NACHT PF05729.12 OAG39940.1 - 2.6e-09 37.2 1.6 3.3e-08 33.6 0.1 3.2 3 1 0 3 3 3 1 NACHT domain AAA_16 PF13191.6 OAG39940.1 - 2.1e-07 31.5 1.5 2e-06 28.3 0.0 3.0 2 1 0 2 2 2 1 AAA ATPase domain Ploopntkinase3 PF18751.1 OAG39940.1 - 0.026 14.5 0.0 0.065 13.1 0.0 1.7 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 AAA_22 PF13401.6 OAG39940.1 - 0.049 13.9 0.1 0.2 11.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.7 OAG39940.1 - 0.088 11.7 0.7 6.9 5.5 0.7 2.3 2 0 0 2 2 2 0 AAA-like domain MMR_HSR1 PF01926.23 OAG39940.1 - 0.1 12.7 0.0 0.78 9.8 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase adh_short PF00106.25 OAG39941.1 - 6.1e-15 55.2 0.1 8.5e-14 51.5 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 OAG39941.1 - 1.1e-07 31.9 0.0 1.9e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG39941.1 - 0.025 14.1 0.1 0.04 13.4 0.1 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAG39941.1 - 0.028 13.8 0.0 0.049 13.0 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 OAG39941.1 - 0.056 12.6 0.0 0.12 11.5 0.0 1.6 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein PglL_A PF15864.5 OAG39941.1 - 0.11 12.2 0.2 0.21 11.4 0.2 1.4 1 0 0 1 1 1 0 Protein glycosylation ligase Fungal_trans_2 PF11951.8 OAG39942.1 - 2.6e-41 141.7 0.0 4.3e-41 141.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Abhydrolase_3 PF07859.13 OAG39943.1 - 6.4e-51 173.2 0.1 8.1e-51 172.9 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OAG39943.1 - 5.1e-06 26.1 0.0 3.2e-05 23.5 0.1 1.9 2 0 0 2 2 2 1 Prolyl oligopeptidase family COesterase PF00135.28 OAG39943.1 - 6.1e-06 25.4 0.0 1.5e-05 24.1 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family Esterase_phd PF10503.9 OAG39943.1 - 0.041 13.4 0.0 0.073 12.5 0.0 1.4 1 0 0 1 1 1 0 Esterase PHB depolymerase AXE1 PF05448.12 OAG39943.1 - 0.047 12.4 0.0 0.07 11.8 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Sugar_tr PF00083.24 OAG39944.1 - 4e-66 223.7 21.4 5e-66 223.4 21.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG39944.1 - 2.1e-17 63.1 27.1 5.3e-17 61.8 22.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily COX1 PF00115.20 OAG39944.1 - 0.0029 16.5 26.5 0.0057 15.6 11.2 2.3 2 0 0 2 2 2 2 Cytochrome C and Quinol oxidase polypeptide I DUF726 PF05277.12 OAG39944.1 - 0.017 14.0 0.1 0.049 12.6 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF726) DUF2178 PF09946.9 OAG39944.1 - 1.7 8.9 6.4 4.6 7.5 0.0 3.4 3 0 0 3 3 3 0 Predicted membrane protein (DUF2178) MFS_1 PF07690.16 OAG39945.1 - 2.6e-33 115.4 33.7 1.7e-31 109.4 17.4 2.5 1 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG39945.1 - 3.3e-08 32.8 10.4 3.3e-08 32.8 10.4 2.2 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.7 OAG39945.1 - 7.5e-05 21.7 0.8 7.5e-05 21.7 0.8 2.3 2 1 1 3 3 3 2 MFS_1 like family TRI12 PF06609.13 OAG39945.1 - 0.00014 20.4 5.0 0.0002 19.9 5.0 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) LapA_dom PF06305.11 OAG39945.1 - 3.9 7.4 9.1 14 5.5 0.1 3.8 4 0 0 4 4 4 0 Lipopolysaccharide assembly protein A domain Fructosamin_kin PF03881.14 OAG39946.1 - 8.8e-25 87.5 0.0 1.1e-24 87.1 0.0 1.1 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 OAG39946.1 - 1e-06 28.9 0.1 1.5e-06 28.3 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family AcetylCoA_hyd_C PF13336.6 OAG39948.1 - 1.8e-43 148.1 0.0 3e-43 147.4 0.0 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain AcetylCoA_hydro PF02550.15 OAG39948.1 - 7.5e-40 137.0 0.1 4.7e-39 134.4 0.1 2.0 1 1 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain Methyltransf_23 PF13489.6 OAG39949.1 - 1.2e-19 70.8 0.0 1.7e-19 70.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG39949.1 - 1.6e-13 51.2 0.0 4.9e-13 49.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG39949.1 - 1.7e-12 47.4 0.0 5.8e-06 26.2 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 OAG39949.1 - 6.6e-11 42.7 0.0 1.2e-10 41.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG39949.1 - 2.7e-07 31.2 0.0 2.1e-06 28.4 0.0 2.4 2 1 0 2 2 1 1 Methyltransferase domain MTS PF05175.14 OAG39949.1 - 1.6e-05 24.5 0.0 3e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.19 OAG39949.1 - 1.7e-05 25.0 0.0 2.6e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_4 PF02390.17 OAG39949.1 - 0.0007 19.1 0.0 0.0048 16.4 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase PrmA PF06325.13 OAG39949.1 - 0.0046 16.4 0.0 0.0069 15.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 OAG39949.1 - 0.013 14.9 0.0 0.067 12.5 0.0 2.2 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.9 OAG39949.1 - 0.021 14.5 0.0 0.032 13.9 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase CMAS PF02353.20 OAG39949.1 - 0.028 13.7 0.0 0.047 13.0 0.0 1.4 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase TPMT PF05724.11 OAG39949.1 - 0.1 12.3 0.0 0.26 10.9 0.0 1.5 2 0 0 2 2 2 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_8 PF05148.15 OAG39949.1 - 0.16 11.8 0.0 0.51 10.1 0.0 1.7 1 1 0 1 1 1 0 Hypothetical methyltransferase p450 PF00067.22 OAG39950.1 - 7.5e-49 166.7 0.0 9.7e-49 166.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SeqA_N PF17206.3 OAG39950.1 - 0.085 12.2 0.1 0.7 9.3 0.2 2.5 2 1 0 2 2 2 0 SeqA protein N-terminal domain Sugar_tr PF00083.24 OAG39951.1 - 8.2e-86 288.6 26.2 9.6e-86 288.4 26.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG39951.1 - 2.2e-11 43.3 40.0 3e-09 36.3 12.7 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily PNKP_ligase PF16542.5 OAG39951.1 - 0.059 12.9 0.0 0.098 12.1 0.0 1.3 1 0 0 1 1 1 0 PNKP adenylyltransferase domain, ligase domain SET PF00856.28 OAG39952.1 - 4.4e-08 33.7 0.1 2e-07 31.6 0.0 2.2 2 0 0 2 2 2 1 SET domain PHD PF00628.29 OAG39952.1 - 0.00022 21.0 10.5 0.00043 20.1 10.5 1.5 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.6 OAG39952.1 - 1.7 8.6 9.3 3.7 7.5 9.3 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 PHD_2 PF13831.6 OAG39952.1 - 4.3 7.0 6.0 7.8 6.1 6.0 1.4 1 0 0 1 1 1 0 PHD-finger FGGY_C PF02782.16 OAG39953.1 - 2e-47 161.5 0.6 2.9e-47 161.0 0.6 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 OAG39953.1 - 5.6e-11 42.5 0.2 3e-09 36.8 0.2 3.0 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain DUF4460 PF14687.6 OAG39953.1 - 0.013 15.5 0.0 0.03 14.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4460) BcrAD_BadFG PF01869.20 OAG39953.1 - 0.11 12.0 0.0 0.59 9.6 0.0 2.1 3 0 0 3 3 3 0 BadF/BadG/BcrA/BcrD ATPase family zf-RING_2 PF13639.6 OAG39954.1 - 2.3e-10 40.6 3.1 4e-10 39.9 3.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 OAG39954.1 - 2e-07 30.7 2.2 2e-07 30.7 2.2 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAG39954.1 - 2.1e-07 30.7 1.6 3.7e-07 29.9 1.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OAG39954.1 - 2.2e-07 30.5 0.2 2.2e-07 30.5 0.2 2.0 2 0 0 2 2 1 1 RING-like zinc finger zf-rbx1 PF12678.7 OAG39954.1 - 8.4e-07 29.2 5.2 2.6e-06 27.6 5.2 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 OAG39954.1 - 2.4e-05 24.2 1.6 3e-05 23.9 0.5 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 OAG39954.1 - 0.0003 20.7 1.4 0.00051 19.9 1.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 OAG39954.1 - 0.00054 19.5 2.7 0.00091 18.8 2.7 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 OAG39954.1 - 0.0067 16.5 0.5 0.011 15.8 0.5 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 OAG39954.1 - 0.018 15.2 1.6 0.04 14.1 1.6 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 OAG39954.1 - 0.022 14.6 1.5 0.044 13.6 1.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 OAG39954.1 - 0.026 14.6 3.6 0.052 13.7 3.6 1.5 1 0 0 1 1 1 0 RING-variant domain Prok-RING_4 PF14447.6 OAG39954.1 - 0.055 13.3 1.6 0.11 12.3 1.6 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 OAG39954.1 - 0.17 11.7 0.9 0.35 10.7 0.9 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.29 OAG39954.1 - 0.19 11.7 2.4 0.39 10.6 2.4 1.5 1 0 0 1 1 1 0 PHD-finger FANCL_C PF11793.8 OAG39954.1 - 2.9 8.1 4.9 11 6.2 4.9 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3H2C3 PF17122.5 OAG39954.1 - 7.2 6.7 7.6 27 4.9 7.6 1.9 1 1 0 1 1 1 0 Zinc-finger IATP PF04568.12 OAG39956.1 - 5e-17 62.1 0.2 5.9e-17 61.9 0.2 1.2 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP HSP20 PF00011.21 OAG39957.1 - 2.7e-09 37.1 0.0 1.5e-06 28.3 0.0 2.2 2 0 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 OAG39957.1 - 0.08 12.5 0.0 9.4 5.9 0.0 2.5 3 0 0 3 3 3 0 HSP20-like domain found in ArsA Cyclase PF04199.13 OAG39960.1 - 1.1e-07 32.2 0.0 1.7e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Putative cyclase BTB PF00651.31 OAG39961.1 - 1.1e-06 28.9 0.1 6.8e-06 26.3 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain HypA PF01155.19 OAG39961.1 - 0.005 16.9 1.1 0.005 16.9 1.1 1.9 2 0 0 2 2 2 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Auxin_inducible PF02519.14 OAG39961.1 - 0.12 12.5 0.0 0.4 10.9 0.0 1.8 1 0 0 1 1 1 0 Auxin responsive protein zinc_ribbon_6 PF14599.6 OAG39961.1 - 0.29 11.2 2.9 0.21 11.7 0.5 2.0 2 0 0 2 2 2 0 Zinc-ribbon Zn-ribbon_8 PF09723.10 OAG39961.1 - 0.31 11.2 2.0 0.85 9.8 2.0 1.8 1 0 0 1 1 1 0 Zinc ribbon domain zinc_ribbon_12 PF11331.8 OAG39961.1 - 6.7 6.6 7.7 1.2 9.0 0.3 2.8 3 0 0 3 3 3 0 Probable zinc-ribbon domain RCC1 PF00415.18 OAG39962.1 - 9.1e-51 170.3 7.1 5.7e-09 36.5 0.0 7.7 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OAG39962.1 - 2.1e-33 113.4 30.2 4.7e-08 32.6 0.8 6.6 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat dCMP_cyt_deam_1 PF00383.23 OAG39963.1 - 6.9e-26 90.1 0.1 8.9e-26 89.7 0.1 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 OAG39963.1 - 2.2e-20 72.8 0.0 2.9e-20 72.4 0.0 1.1 1 0 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 OAG39963.1 - 0.0018 18.3 1.7 0.19 11.8 1.7 2.3 1 1 0 1 1 1 1 Bd3614-like deaminase SNAD4 PF18750.1 OAG39963.1 - 0.0025 17.9 0.0 0.0042 17.2 0.0 1.3 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC3 PF18771.1 OAG39963.1 - 0.0048 17.0 0.0 0.0074 16.4 0.0 1.2 1 0 0 1 1 1 1 APOBEC3 NAD2 PF18782.1 OAG39963.1 - 0.027 14.6 0.0 0.038 14.1 0.0 1.2 1 0 0 1 1 1 0 Novel AID APOBEC clade 2 APOBEC4_like PF18774.1 OAG39963.1 - 0.03 14.2 0.0 0.043 13.8 0.0 1.3 1 0 0 1 1 1 0 APOBEC4-like -AID/APOBEC-deaminase NAD1 PF18778.1 OAG39963.1 - 0.051 13.7 0.0 0.072 13.2 0.0 1.2 1 0 0 1 1 1 0 Novel AID APOBEC clade 1 APOBEC2 PF18772.1 OAG39963.1 - 0.054 13.5 0.0 0.077 13.0 0.0 1.2 1 0 0 1 1 1 0 APOBEC2 APOBEC_N PF08210.11 OAG39963.1 - 0.083 12.8 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 APOBEC-like N-terminal domain CAP_N PF01213.19 OAG39964.1 - 0.058 12.9 1.3 0.093 12.2 1.3 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal MBA1 PF07961.11 OAG39964.1 - 0.19 10.8 0.0 3.7 6.5 0.0 2.1 2 0 0 2 2 2 0 MBA1-like protein Cytochrom_B558a PF05038.13 OAG39964.1 - 0.45 10.1 2.4 0.86 9.1 2.4 1.4 1 0 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit ADH_N PF08240.12 OAG39966.1 - 3e-25 88.2 0.9 6.2e-25 87.2 0.9 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG39966.1 - 2.1e-19 69.8 0.1 3.9e-19 68.9 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAG39966.1 - 1.1e-06 29.7 0.1 2.5e-06 28.6 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 OAG39966.1 - 0.028 13.7 0.3 0.04 13.2 0.3 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain BKACE PF05853.12 OAG39966.1 - 0.037 13.3 0.0 0.056 12.7 0.0 1.2 1 0 0 1 1 1 0 beta-keto acid cleavage enzyme adh_short PF00106.25 OAG39966.1 - 1.4 8.3 3.9 0.27 10.7 0.1 1.7 2 0 0 2 2 2 0 short chain dehydrogenase Aldedh PF00171.22 OAG39967.1 - 1.2e-160 535.0 0.0 1.4e-160 534.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 OAG39967.1 - 6.9e-05 22.4 0.1 0.004 16.6 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) LuxC PF05893.14 OAG39967.1 - 0.15 11.1 0.2 0.24 10.4 0.2 1.2 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) Tetraspanin PF00335.20 OAG39968.1 - 0.00026 20.8 0.0 0.0014 18.4 0.0 1.9 2 0 0 2 2 2 1 Tetraspanin family Phage_holin_2_4 PF16082.5 OAG39968.1 - 0.0043 16.7 1.1 0.01 15.5 0.1 2.2 2 0 0 2 2 2 1 Bacteriophage holin family, superfamily II-like 7tm_3 PF00003.22 OAG39968.1 - 0.013 15.3 0.4 0.023 14.4 0.5 1.4 1 1 0 1 1 1 0 7 transmembrane sweet-taste receptor of 3 GCPR DUF4199 PF13858.6 OAG39968.1 - 0.06 13.8 0.8 0.14 12.5 0.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF4199) Wzy_C PF04932.15 OAG39968.1 - 0.24 11.0 3.7 0.43 10.2 3.7 1.6 1 1 0 1 1 1 0 O-Antigen ligase Mem_trans PF03547.18 OAG39968.1 - 0.29 9.5 2.9 0.89 7.9 0.0 2.1 1 1 1 2 2 2 0 Membrane transport protein DUF1206 PF06724.11 OAG39968.1 - 0.51 10.4 4.7 0.97 9.6 0.0 2.8 2 1 0 2 2 2 0 Domain of Unknown Function (DUF1206) DUF4131 PF13567.6 OAG39968.1 - 0.62 9.7 3.5 0.82 9.3 0.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) SpoIIM PF01944.17 OAG39968.1 - 0.87 9.6 6.5 0.48 10.4 2.0 2.4 3 0 0 3 3 3 0 Stage II sporulation protein M DUF1772 PF08592.11 OAG39968.1 - 2.4 8.5 7.3 3.3 8.0 4.6 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) Y_phosphatase PF00102.27 OAG39969.1 - 4.9e-60 203.0 0.0 6.9e-59 199.3 0.0 2.3 1 1 0 1 1 1 1 Protein-tyrosine phosphatase Rhodanese PF00581.20 OAG39969.1 - 1.5e-06 28.7 0.0 3.5e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain DSPc PF00782.20 OAG39969.1 - 0.0077 16.0 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 OAG39969.1 - 0.037 14.0 0.2 0.093 12.7 0.2 1.6 1 0 0 1 1 1 0 Tyrosine phosphatase family SelP_N PF04592.14 OAG39969.1 - 4.8 6.5 10.9 14 5.0 10.9 1.7 1 0 0 1 1 1 0 Selenoprotein P, N terminal region COX16 PF14138.6 OAG39970.1 - 5.2e-30 103.8 0.1 7e-30 103.4 0.1 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 HET PF06985.11 OAG39971.1 - 7e-10 39.4 0.0 1.6e-06 28.5 0.0 2.6 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) HLH PF00010.26 OAG39972.1 - 1.8e-09 37.4 0.1 4.4e-09 36.2 0.0 1.7 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain DTHCT PF08070.11 OAG39972.1 - 0.12 13.1 7.1 0.33 11.7 6.4 2.1 1 1 0 1 1 1 0 DTHCT (NUC029) region DUF4107 PF13389.6 OAG39972.1 - 0.63 10.2 2.1 4.9 7.3 0.8 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF4107) MARVEL PF01284.23 OAG39974.1 - 0.023 14.8 16.3 0.052 13.6 15.6 1.8 1 1 1 2 2 2 0 Membrane-associating domain Herpes_UL79 PF03049.14 OAG39974.1 - 0.051 13.2 0.3 0.077 12.7 0.3 1.2 1 0 0 1 1 1 0 UL79 family DUF202 PF02656.15 OAG39974.1 - 0.31 11.5 5.1 6.4 7.3 0.4 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF202) Nic96 PF04097.14 OAG39976.1 - 4.9e-195 649.6 0.0 6e-195 649.3 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 OPT PF03169.15 OAG39977.1 - 1.3e-202 674.8 36.8 1.5e-202 674.6 36.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein FliMN_C PF01052.20 OAG39978.1 - 0.0026 17.7 0.0 0.0052 16.7 0.0 1.4 1 0 0 1 1 1 1 Type III flagellar switch regulator (C-ring) FliN C-term Rep-A_N PF04057.12 OAG39978.1 - 0.029 14.4 0.0 0.048 13.7 0.0 1.3 1 0 0 1 1 1 0 Replication factor-A protein 1, N-terminal domain Fe-ADH PF00465.19 OAG39979.1 - 1.3e-66 224.9 0.1 1.7e-66 224.5 0.1 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 OAG39979.1 - 3e-09 37.0 0.1 0.00011 22.0 0.1 2.1 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Aldo_ket_red PF00248.21 OAG39980.1 - 2.2e-52 178.1 0.0 2.7e-52 177.8 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family SecG PF03840.14 OAG39981.1 - 0.73 10.0 0.0 0.73 10.0 0.0 2.4 3 1 0 3 3 3 0 Preprotein translocase SecG subunit Dabb PF07876.12 OAG39982.1 - 4.2e-17 62.5 0.0 4.7e-17 62.4 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain DUF3638 PF12340.8 OAG39983.1 - 8.9e-87 290.1 0.1 2e-86 289.0 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 OAG39983.1 - 8e-11 41.1 0.0 1.6e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) Lyase_aromatic PF00221.19 OAG39984.1 - 4e-141 470.8 3.8 8e-140 466.6 3.8 2.0 1 1 0 1 1 1 1 Aromatic amino acid lyase Beta-lactamase PF00144.24 OAG39985.1 - 3.3e-45 154.8 0.1 5.1e-45 154.1 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase PAM2 PF07145.15 OAG39986.1 - 8.1e-05 22.0 12.5 0.17 11.7 0.1 4.7 4 1 0 4 4 4 3 Ataxin-2 C-terminal region YflT PF11181.8 OAG39986.1 - 4.1 8.0 9.8 1.5 9.4 2.8 3.4 2 0 0 2 2 2 0 Heat induced stress protein YflT NPV_P10 PF05531.12 OAG39986.1 - 4.6 7.8 21.9 7 7.2 1.1 6.0 4 1 0 5 5 5 0 Nucleopolyhedrovirus P10 protein Fungal_trans_2 PF11951.8 OAG39987.1 - 4.2e-08 32.4 0.1 9.4e-08 31.3 0.1 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Thioredoxin_6 PF13848.6 OAG39988.1 - 1.7e-31 109.6 0.5 2.4e-25 89.5 0.4 2.1 1 1 1 2 2 2 2 Thioredoxin-like domain Thioredoxin PF00085.20 OAG39988.1 - 3.5e-18 65.5 0.0 1.3e-15 57.2 0.0 2.8 3 0 0 3 3 3 2 Thioredoxin ERp29_N PF07912.13 OAG39988.1 - 0.029 14.5 0.0 10 6.2 0.0 3.1 2 1 0 3 3 3 0 ERp29, N-terminal domain UQ_con PF00179.26 OAG39989.1 - 4.1e-36 123.7 0.0 7.1e-36 122.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme 2OG-FeII_Oxy_3 PF13640.6 OAG39989.1 - 1.6e-06 28.9 0.0 3.3e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Prok-E2_B PF14461.6 OAG39989.1 - 0.0059 16.3 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic E2 family B PIR PF00399.19 OAG39990.1 - 0.00047 19.6 0.8 0.00047 19.6 0.8 2.4 2 0 0 2 2 2 1 Yeast PIR protein repeat MMgT PF10270.9 OAG39991.1 - 2.6e-34 117.6 0.0 3e-34 117.4 0.0 1.0 1 0 0 1 1 1 1 Membrane magnesium transporter PEX11 PF05648.14 OAG39992.1 - 2.2e-18 66.5 0.0 3.2e-16 59.5 0.0 2.4 2 1 0 2 2 2 2 Peroxisomal biogenesis factor 11 (PEX11) Inhibitor_I53 PF11714.8 OAG39992.1 - 0.1 12.8 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 Thrombin inhibitor Madanin Phosphoesterase PF04185.14 OAG39993.1 - 2.4e-60 204.6 6.3 5.1e-60 203.5 6.3 1.5 1 1 0 1 1 1 1 Phosphoesterase family VIT1 PF01988.19 OAG39994.1 - 2e-61 207.6 3.7 3e-61 207.0 3.7 1.2 1 0 0 1 1 1 1 VIT family MARVEL PF01284.23 OAG39994.1 - 0.00016 21.7 2.8 0.00029 20.9 2.8 1.3 1 0 0 1 1 1 1 Membrane-associating domain SLATT_fungal PF18142.1 OAG39994.1 - 0.56 10.2 3.9 0.12 12.4 0.4 1.8 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain ABC2_membrane PF01061.24 OAG39995.1 - 4.2e-69 232.2 61.9 1.6e-37 128.9 18.8 3.5 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 OAG39995.1 - 5.3e-38 130.6 0.0 1.5e-19 70.9 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 OAG39995.1 - 4.3e-24 84.2 6.3 8.4e-22 76.9 0.1 3.4 3 0 0 3 3 3 2 CDR ABC transporter ABC_trans_N PF14510.6 OAG39995.1 - 1.5e-15 57.5 0.0 4.1e-15 56.2 0.0 1.7 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 OAG39995.1 - 5.1e-07 30.2 0.1 0.0083 16.5 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain ABC2_membrane_3 PF12698.7 OAG39995.1 - 1.4e-05 24.4 11.8 1.4e-05 24.4 11.8 3.2 3 1 0 3 3 2 1 ABC-2 family transporter protein AAA_21 PF13304.6 OAG39995.1 - 1.9e-05 24.7 0.9 0.04 13.7 0.1 3.0 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 OAG39995.1 - 0.00033 20.6 1.6 0.00068 19.6 0.1 2.0 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 OAG39995.1 - 0.00042 20.6 0.6 0.054 13.8 0.1 3.2 3 1 0 3 3 3 1 AAA domain AAA_33 PF13671.6 OAG39995.1 - 0.00048 20.3 0.2 0.17 12.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 OAG39995.1 - 0.00091 19.8 0.0 0.039 14.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 OAG39995.1 - 0.00099 18.8 1.6 0.029 14.1 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.6 OAG39995.1 - 0.0031 17.1 0.2 0.087 12.4 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 OAG39995.1 - 0.01 15.6 0.3 0.58 9.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 OAG39995.1 - 0.011 15.0 0.0 0.14 11.4 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA PF00004.29 OAG39995.1 - 0.016 15.7 0.5 4.6 7.7 0.2 3.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 OAG39995.1 - 0.018 15.0 3.3 1.3 8.9 0.1 3.0 3 0 0 3 3 2 0 NACHT domain MMR_HSR1 PF01926.23 OAG39995.1 - 0.022 14.8 0.3 0.76 9.9 0.2 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase FeoB_N PF02421.18 OAG39995.1 - 0.025 14.1 0.2 0.081 12.4 0.1 1.9 2 0 0 2 2 2 0 Ferrous iron transport protein B T2SSE PF00437.20 OAG39995.1 - 0.042 12.9 0.5 1.9 7.5 0.1 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein DUF3278 PF11683.8 OAG39995.1 - 0.042 13.9 1.8 7.4 6.7 0.5 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3278) SMC_N PF02463.19 OAG39995.1 - 0.047 13.1 0.1 3.1 7.2 0.0 3.0 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_24 PF13479.6 OAG39995.1 - 0.088 12.5 0.8 0.79 9.4 0.1 2.2 2 0 0 2 2 2 0 AAA domain MobB PF03205.14 OAG39995.1 - 0.1 12.5 0.6 0.32 10.9 0.0 2.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B TsaE PF02367.17 OAG39995.1 - 0.25 11.3 0.9 3.9 7.5 0.1 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE cobW PF02492.19 OAG39995.1 - 0.6 9.7 4.0 0.34 10.5 0.2 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MLANA PF14991.6 OAG39996.1 - 0.1 12.9 0.7 0.22 11.8 0.4 1.6 1 1 1 2 2 2 0 Protein melan-A Protoglobin PF11563.8 OAG39997.1 - 8.7e-37 126.5 0.0 1e-36 126.2 0.0 1.1 1 0 0 1 1 1 1 Protoglobin Ribosomal_L37 PF08561.10 OAG39998.1 - 1.4e-36 125.6 1.4 2e-36 125.2 1.4 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L37 RRM_1 PF00076.22 OAG40000.1 - 3.8e-39 132.4 0.0 2.8e-18 65.5 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OAG40000.1 - 1.9e-05 24.7 0.0 0.31 11.2 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif RRM_occluded PF16842.5 OAG40000.1 - 0.16 11.9 0.0 0.36 10.7 0.0 1.6 1 0 0 1 1 1 0 Occluded RNA-recognition motif Alg6_Alg8 PF03155.15 OAG40001.1 - 7.8e-131 437.4 16.6 1.4e-82 278.2 7.6 2.1 2 0 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family Fasciclin PF02469.22 OAG40002.1 - 0.00037 20.7 0.0 0.00056 20.1 0.0 1.3 1 0 0 1 1 1 1 Fasciclin domain VWA_2 PF13519.6 OAG40002.1 - 0.1 13.3 0.0 0.16 12.6 0.0 1.3 1 0 0 1 1 1 0 von Willebrand factor type A domain Sugar_tr PF00083.24 OAG40005.1 - 1.1e-77 261.9 30.1 1.2e-77 261.7 30.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG40005.1 - 5.8e-17 61.6 65.8 3.3e-13 49.3 35.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Transgly_assoc PF04226.13 OAG40005.1 - 8.1 6.8 13.0 1.1 9.6 3.0 3.6 2 1 1 3 3 3 0 Transglycosylase associated protein ADH_zinc_N PF00107.26 OAG40006.1 - 2.9e-25 88.7 0.0 5e-25 88.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG40006.1 - 1.5e-23 82.8 0.2 3.1e-23 81.8 0.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 OAG40006.1 - 2.4e-06 28.7 0.0 3.3e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 OAG40006.1 - 0.00012 21.4 0.4 0.00022 20.6 0.4 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 OAG40006.1 - 0.00072 19.0 0.2 0.0016 17.8 0.2 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_25 PF13649.6 OAG40006.1 - 0.00093 19.9 0.1 0.0017 19.0 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain TrkA_N PF02254.18 OAG40006.1 - 0.0017 18.6 0.1 0.0027 18.0 0.1 1.3 1 0 0 1 1 1 1 TrkA-N domain CMAS PF02353.20 OAG40006.1 - 0.006 15.9 0.1 0.0089 15.3 0.1 1.4 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 OAG40006.1 - 0.016 15.8 0.1 0.032 14.9 0.1 1.6 1 0 0 1 1 1 0 Methyltransferase domain BKACE PF05853.12 OAG40006.1 - 0.031 13.6 0.0 0.042 13.1 0.0 1.3 1 0 0 1 1 1 0 beta-keto acid cleavage enzyme PglD_N PF17836.1 OAG40006.1 - 0.034 14.8 0.2 0.068 13.8 0.2 1.5 1 0 0 1 1 1 0 PglD N-terminal domain Methyltransf_31 PF13847.6 OAG40006.1 - 0.048 13.5 0.1 0.21 11.4 0.1 1.9 2 0 0 2 2 2 0 Methyltransferase domain Mur_ligase PF01225.25 OAG40006.1 - 0.089 13.1 0.8 0.32 11.4 0.2 2.4 2 1 0 2 2 2 0 Mur ligase family, catalytic domain AMP-binding PF00501.28 OAG40007.1 - 3.4e-62 210.4 0.0 5.7e-62 209.7 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 OAG40007.1 - 3.9e-30 104.9 0.0 6.1e-30 104.2 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 OAG40007.1 - 4.5e-10 39.4 0.0 7.9e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 OAG40007.1 - 1.6e-05 25.2 0.2 4e-05 23.9 0.2 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.19 OAG40007.1 - 0.00091 18.3 0.0 0.12 11.4 0.0 2.3 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding_C PF13193.6 OAG40007.1 - 0.0037 18.2 0.0 0.018 16.0 0.0 2.3 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Fungal_trans PF04082.18 OAG40008.1 - 2.6e-20 72.6 0.1 4.1e-20 71.9 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG40008.1 - 1.1e-05 25.4 8.6 2.2e-05 24.4 8.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4005 PF13178.6 OAG40008.1 - 0.1 13.2 4.0 0.18 12.5 2.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4005) FMO-like PF00743.19 OAG40009.1 - 4.7e-21 74.8 0.2 2e-19 69.4 0.0 2.2 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 OAG40009.1 - 2.7e-14 53.1 0.0 1e-11 44.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG40009.1 - 6.3e-14 51.9 0.0 7.4e-12 45.1 0.0 2.4 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 OAG40009.1 - 1.5e-09 37.5 0.0 3e-08 33.3 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG40009.1 - 5e-09 36.3 0.0 4.4e-06 26.8 0.0 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 OAG40009.1 - 1.1e-05 25.4 0.4 0.011 15.7 0.1 3.6 3 1 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.24 OAG40009.1 - 0.00076 19.2 0.0 0.09 12.3 0.0 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 OAG40009.1 - 0.0019 18.7 0.0 0.065 13.8 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 OAG40009.1 - 0.015 15.7 0.0 2.6 8.6 0.0 3.1 3 0 0 3 3 3 0 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.19 OAG40009.1 - 0.028 13.8 0.1 0.073 12.4 0.0 1.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 OAG40009.1 - 0.037 14.1 0.4 0.34 11.0 0.0 2.4 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.14 OAG40009.1 - 0.042 12.5 0.4 1.5 7.4 0.1 2.4 2 0 0 2 2 2 0 HI0933-like protein Aldo_ket_red PF00248.21 OAG40011.1 - 6e-66 222.6 0.0 1.1e-65 221.8 0.0 1.4 1 0 0 1 1 1 1 Aldo/keto reductase family Fungal_trans PF04082.18 OAG40011.1 - 0.03 13.4 0.0 0.056 12.5 0.0 1.4 1 0 0 1 1 1 0 Fungal specific transcription factor domain Clr5 PF14420.6 OAG40013.1 - 5e-12 45.9 2.9 8.2e-12 45.2 1.5 2.1 2 0 0 2 2 2 1 Clr5 domain adh_short_C2 PF13561.6 OAG40015.1 - 5.1e-45 153.8 0.0 1.1e-44 152.8 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG40015.1 - 2.9e-30 105.2 0.0 5.5e-30 104.3 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG40015.1 - 8.5e-07 29.1 0.0 2.3e-06 27.6 0.0 1.7 2 0 0 2 2 2 1 KR domain DERM PF14704.6 OAG40015.1 - 0.0071 16.8 0.0 0.013 16.0 0.0 1.4 1 0 0 1 1 1 1 Dermatopontin Epimerase PF01370.21 OAG40015.1 - 0.014 14.9 0.0 0.019 14.5 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 OAG40015.1 - 0.019 14.1 0.0 0.039 13.0 0.0 1.5 2 0 0 2 2 2 0 RmlD substrate binding domain ApbA PF02558.16 OAG40015.1 - 0.046 13.4 0.0 0.072 12.7 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA SHD1 PF03983.12 OAG40016.1 - 7.8e-33 112.1 0.0 1.5e-32 111.3 0.0 1.4 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_1 PF00018.28 OAG40016.1 - 9.6e-33 111.6 10.2 4.2e-13 48.7 0.2 4.4 4 0 0 4 4 4 3 SH3 domain SH3_9 PF14604.6 OAG40016.1 - 4.2e-28 97.0 8.4 5.5e-11 42.1 0.1 3.6 3 0 0 3 3 3 3 Variant SH3 domain SH3_2 PF07653.17 OAG40016.1 - 3.1e-18 65.2 0.0 2.1e-06 27.3 0.0 4.4 4 0 0 4 4 4 4 Variant SH3 domain DUF1720 PF08226.11 OAG40016.1 - 2.7e-07 30.9 34.4 2.7e-07 30.9 34.4 6.5 2 1 3 5 5 5 2 Domain of unknown function (DUF1720) SH3_10 PF17902.1 OAG40016.1 - 0.0003 20.8 0.1 0.14 12.2 0.0 3.4 3 0 0 3 3 3 1 SH3 domain SAM_4 PF18017.1 OAG40016.1 - 0.013 15.4 0.0 0.032 14.2 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) SH3_3 PF08239.11 OAG40016.1 - 0.06 13.6 8.5 0.26 11.6 0.9 3.5 4 0 0 4 4 4 0 Bacterial SH3 domain PRKCSH PF07915.13 OAG40017.1 - 1.8e-19 70.5 1.6 2.4e-19 70.1 0.1 2.0 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein TFIIA PF03153.13 OAG40017.1 - 0.044 13.8 4.8 0.09 12.8 4.8 1.6 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PRKCSH_1 PF13015.6 OAG40017.1 - 0.059 13.1 0.2 0.16 11.6 0.0 1.9 2 0 0 2 2 2 0 Glucosidase II beta subunit-like protein LRR_6 PF13516.6 OAG40018.1 - 2.1e-19 67.9 2.4 0.022 14.8 0.0 7.6 8 0 0 8 8 8 5 Leucine Rich repeat LRR_4 PF12799.7 OAG40018.1 - 2.8e-07 30.7 14.9 0.96 10.0 0.6 6.1 5 2 1 7 7 7 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OAG40018.1 - 0.0001 22.3 0.4 2.1e+02 3.1 0.0 6.3 7 0 0 7 7 7 0 Leucine Rich Repeat LRR_8 PF13855.6 OAG40018.1 - 0.00064 19.4 10.7 9.1 6.1 0.1 5.9 5 2 0 5 5 5 3 Leucine rich repeat DUF604 PF04646.12 OAG40018.1 - 0.063 12.7 0.2 1.6 8.1 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function, DUF604 RR_TM4-6 PF06459.12 OAG40018.1 - 3.8 7.2 14.1 6 6.6 14.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DNA_pol_phi PF04931.13 OAG40018.1 - 8.2 4.4 25.4 13 3.8 25.4 1.2 1 0 0 1 1 1 0 DNA polymerase phi EMC3_TMCO1 PF01956.16 OAG40019.1 - 4.9e-54 182.6 0.3 6.7e-54 182.1 0.3 1.2 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like DUF576 PF04507.12 OAG40020.1 - 0.032 13.7 0.0 0.035 13.6 0.0 1.1 1 0 0 1 1 1 0 Csa1 family GRAS PF03514.14 OAG40021.1 - 0.057 12.3 0.4 0.077 11.9 0.4 1.1 1 0 0 1 1 1 0 GRAS domain family NDUFA12 PF05071.16 OAG40022.1 - 4.8e-11 43.3 4.8 1e-10 42.3 4.8 1.7 1 1 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 CH PF00307.31 OAG40023.1 - 1.9e-14 53.8 0.0 4.2e-14 52.7 0.0 1.6 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 OAG40023.1 - 0.16 11.8 0.0 0.35 10.7 0.0 1.5 1 0 0 1 1 1 0 CAMSAP CH domain DUF4677 PF15726.5 OAG40023.1 - 1.9 8.6 4.3 1 9.5 0.1 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4677) PBP1_TM PF14812.6 OAG40024.1 - 8 6.9 9.1 3.3 8.1 4.2 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FAD_binding_3 PF01494.19 OAG40025.1 - 2e-18 66.8 0.4 8.1e-18 64.8 0.4 1.9 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAG40025.1 - 1.1e-07 31.8 0.2 2.8e-07 30.5 0.1 1.7 1 1 1 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAG40025.1 - 1.2e-05 25.4 0.2 4e-05 23.8 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAG40025.1 - 2.9e-05 23.4 0.2 0.002 17.4 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAG40025.1 - 0.001 19.1 0.3 0.22 11.5 0.2 2.6 3 0 0 3 3 3 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 OAG40025.1 - 0.0023 17.1 0.8 0.0037 16.4 0.8 1.3 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.14 OAG40025.1 - 0.005 15.7 0.9 0.046 12.6 0.4 2.1 2 0 0 2 2 2 1 Tryptophan halogenase HI0933_like PF03486.14 OAG40025.1 - 0.0064 15.2 0.1 0.01 14.6 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein SE PF08491.10 OAG40025.1 - 0.0096 15.0 0.0 0.22 10.5 0.0 2.2 2 0 0 2 2 2 1 Squalene epoxidase Amino_oxidase PF01593.24 OAG40025.1 - 0.036 13.3 0.0 4.1 6.6 0.0 2.3 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 OAG40025.1 - 0.046 14.3 0.4 0.14 12.7 0.4 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAG40025.1 - 0.1 11.9 0.1 0.18 11.0 0.1 1.4 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.12 OAG40025.1 - 0.11 11.6 0.3 1 8.3 0.1 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein GIDA PF01134.22 OAG40025.1 - 0.18 10.8 0.5 0.32 10.0 0.5 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 OAG40025.1 - 0.27 10.5 2.8 1.3 8.2 1.4 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ADH_N PF08240.12 OAG40026.1 - 8.7e-22 77.1 1.2 1.4e-21 76.4 1.2 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG40026.1 - 2.1e-14 53.6 0.0 3.3e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 OAG40026.1 - 2.6e-06 27.1 0.0 4e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 OAG40026.1 - 0.00023 22.2 0.0 0.0004 21.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 OAG40026.1 - 0.0017 18.3 0.1 0.005 16.7 0.0 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-associated DAO PF01266.24 OAG40026.1 - 0.07 12.7 2.0 5.6 6.4 2.4 2.1 1 1 0 2 2 2 0 FAD dependent oxidoreductase MatE PF01554.18 OAG40027.1 - 6.2e-09 35.7 15.8 8.1e-05 22.3 2.7 3.5 3 1 0 3 3 3 3 MatE Polysacc_synt_C PF14667.6 OAG40027.1 - 0.0014 18.7 6.0 0.0014 18.7 6.0 3.2 4 0 0 4 4 4 1 Polysaccharide biosynthesis C-terminal domain Aminotran_1_2 PF00155.21 OAG40028.1 - 2.4e-46 158.6 0.0 2.8e-46 158.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Nbl1_Borealin_N PF10444.9 OAG40029.1 - 1.1e-19 69.7 6.2 2e-19 69.0 6.2 1.4 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal DUF3546 PF12066.8 OAG40030.1 - 8.7e-33 112.8 5.4 8.7e-33 112.8 5.4 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF3546) DUF4187 PF13821.6 OAG40030.1 - 1.4e-12 47.2 0.2 3.3e-12 46.0 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) ARS2 PF04959.13 OAG40030.1 - 2.1e-11 44.6 0.7 2.1e-11 44.6 0.7 2.9 2 1 1 3 3 3 1 Arsenite-resistance protein 2 TspO_MBR PF03073.15 OAG40031.1 - 5.3e-45 152.8 5.2 8.9e-45 152.1 5.2 1.4 1 1 0 1 1 1 1 TspO/MBR family Zip PF02535.22 OAG40032.1 - 4.4e-51 174.1 1.3 5.3e-51 173.8 1.3 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter PEP_mutase PF13714.6 OAG40033.1 - 3.6e-49 167.4 0.1 5.2e-49 166.9 0.1 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 OAG40033.1 - 6.4e-07 28.2 0.0 0.00011 20.9 0.0 2.1 2 0 0 2 2 2 2 Isocitrate lyase family Pantoate_transf PF02548.15 OAG40033.1 - 0.00029 20.3 0.2 0.016 14.6 0.0 2.2 2 0 0 2 2 2 2 Ketopantoate hydroxymethyltransferase BtpA PF03437.15 OAG40033.1 - 0.13 11.7 0.1 0.8 9.1 0.0 2.0 2 0 0 2 2 2 0 BtpA family Zn_clus PF00172.18 OAG40034.1 - 4.3e-07 29.9 10.4 8e-07 29.1 10.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gpr1_Fun34_YaaH PF01184.19 OAG40035.1 - 3.6e-31 108.4 17.2 4.4e-31 108.1 17.2 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF2206 PF09971.9 OAG40035.1 - 0.37 9.5 3.2 0.65 8.7 3.2 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) Aldedh PF00171.22 OAG40036.1 - 6.2e-149 496.4 0.0 7e-149 496.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 OAG40036.1 - 0.038 13.4 0.0 0.29 10.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) FAD_binding_2 PF00890.24 OAG40037.1 - 1.4e-37 129.8 0.0 1.9e-37 129.3 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAG40037.1 - 6.1e-05 22.8 0.5 0.00032 20.4 0.4 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG40037.1 - 0.0083 15.4 0.1 0.02 14.1 0.1 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAG40037.1 - 0.038 14.5 0.4 6.7 7.4 0.0 3.2 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Abhydrolase_6 PF12697.7 OAG40038.1 - 1.1e-12 49.1 9.1 6.6e-11 43.2 9.1 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAG40038.1 - 1.4e-07 31.5 0.0 2.3e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAG40038.1 - 0.0015 17.8 0.0 1.6 7.9 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 PHP_C PF13263.6 OAG40039.1 - 0.0026 17.5 0.0 0.0049 16.6 0.0 1.5 1 0 0 1 1 1 1 PHP-associated Scytalone_dh PF02982.14 OAG40040.1 - 3.9e-84 280.3 1.7 5e-84 279.9 1.7 1.1 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.6 OAG40040.1 - 2.5e-06 27.6 0.3 3.9e-06 27.0 0.3 1.3 1 0 0 1 1 1 1 SnoaL-like domain Vint PF14623.6 OAG40041.1 - 4.5e-53 179.5 0.0 7.5e-53 178.8 0.0 1.4 1 0 0 1 1 1 1 Hint-domain Vwaint PF14624.6 OAG40041.1 - 1.3e-22 79.7 0.0 3.1e-22 78.5 0.0 1.7 1 0 0 1 1 1 1 VWA / Hh protein intein-like VWA_2 PF13519.6 OAG40041.1 - 2.2e-12 47.6 0.0 4.5e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 OAG40041.1 - 3.7e-12 46.9 0.0 6.5e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 OAG40041.1 - 1.1e-07 32.0 0.1 1.4e-05 25.1 0.0 3.1 3 1 0 3 3 3 1 von Willebrand factor type A domain Epimerase PF01370.21 OAG40042.1 - 1.3e-12 47.7 0.0 2.1e-12 47.0 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OAG40042.1 - 2.2e-07 30.2 0.0 3.2e-07 29.6 0.0 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 OAG40042.1 - 1.2e-06 28.1 0.0 1.8e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 OAG40042.1 - 2e-05 24.6 0.0 6.3e-05 22.9 0.0 1.8 2 1 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 OAG40042.1 - 0.00074 19.1 0.1 0.0011 18.6 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.25 OAG40042.1 - 0.0021 17.5 0.1 0.0061 16.0 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_4 PF07993.12 OAG40042.1 - 0.0047 16.1 0.0 0.2 10.8 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein Mistic PF11458.8 OAG40042.1 - 0.082 12.9 0.0 0.3 11.1 0.0 1.9 1 0 0 1 1 1 0 Membrane-integrating protein Mistic RmlD_sub_bind PF04321.17 OAG40042.1 - 0.12 11.4 0.0 0.25 10.4 0.0 1.5 2 0 0 2 2 2 0 RmlD substrate binding domain HLH PF00010.26 OAG40043.1 - 4.4e-16 58.6 0.7 8e-16 57.7 0.7 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain RNR_Alpha PF17975.1 OAG40043.1 - 0.11 13.0 1.1 0.2 12.1 1.1 1.4 1 0 0 1 1 1 0 Ribonucleotide reductase alpha domain DASH_Dam1 PF08653.10 OAG40043.1 - 0.31 10.9 0.8 32 4.4 0.0 2.5 2 0 0 2 2 2 0 DASH complex subunit Dam1 DUF4509 PF14970.6 OAG40043.1 - 0.35 10.8 2.4 0.54 10.2 2.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4509) BLOC1_2 PF10046.9 OAG40043.1 - 1 9.7 4.5 1.9 8.8 4.5 1.4 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF724 PF05266.14 OAG40043.1 - 1 9.1 7.8 1.7 8.5 7.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Exonuc_VII_L PF02601.15 OAG40043.1 - 1.4 8.4 3.7 1.9 8.0 3.7 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit CENP-F_leu_zip PF10473.9 OAG40043.1 - 5.9 6.9 10.2 7.6 6.6 7.9 1.9 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PSDC PF12588.8 OAG40044.1 - 1.2e-56 190.5 0.0 2.1e-56 189.8 0.0 1.4 1 0 0 1 1 1 1 Phophatidylserine decarboxylase PS_Dcarbxylase PF02666.15 OAG40044.1 - 9.6e-37 126.5 0.0 3.4e-36 124.7 0.0 1.8 2 0 0 2 2 2 1 Phosphatidylserine decarboxylase Biotin_lipoyl_2 PF13533.6 OAG40044.1 - 0.004 16.9 0.7 0.1 12.5 0.2 2.5 2 0 0 2 2 2 1 Biotin-lipoyl like Peptidase_M23 PF01551.22 OAG40044.1 - 0.14 12.4 0.0 0.4 10.9 0.0 1.7 1 0 0 1 1 1 0 Peptidase family M23 HPP PF04982.13 OAG40045.1 - 3.8e-43 146.6 4.9 3.8e-43 146.6 4.9 1.7 2 0 0 2 2 2 1 HPP family DUF2476 PF10630.9 OAG40045.1 - 7.7 6.6 6.7 11 6.1 6.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2476) Peptidase_M1 PF01433.20 OAG40046.1 - 7.6e-46 156.4 0.7 1.1e-45 155.9 0.7 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 OAG40046.1 - 3.8e-37 126.8 0.0 1e-36 125.5 0.0 1.8 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 OAG40046.1 - 1.8e-28 100.0 0.0 2.8e-28 99.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_MA_2 PF13485.6 OAG40046.1 - 0.034 13.8 0.0 0.23 11.1 0.0 2.0 2 0 0 2 2 2 0 Peptidase MA superfamily Peptidase_M61 PF05299.12 OAG40046.1 - 1.1 9.6 4.8 6.4 7.2 2.6 2.9 2 1 0 2 2 2 0 M61 glycyl aminopeptidase Gpr1_Fun34_YaaH PF01184.19 OAG40047.1 - 2.4e-31 109.0 18.3 2.9e-31 108.7 18.3 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family WD40 PF00400.32 OAG40048.1 - 1.3e-06 29.0 7.0 1.2 10.1 0.5 4.7 4 0 0 4 4 4 3 WD domain, G-beta repeat Ureidogly_lyase PF04115.12 OAG40049.1 - 2.4e-56 190.5 0.0 2.8e-56 190.2 0.0 1.1 1 0 0 1 1 1 1 Ureidoglycolate lyase zf-RING_2 PF13639.6 OAG40050.1 - 4.7e-07 30.0 7.8 1e-06 28.9 7.8 1.6 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.8 OAG40050.1 - 9.7e-06 25.7 3.6 2.3e-05 24.5 3.6 1.6 1 0 0 1 1 1 1 FANCL C-terminal domain zf-ANAPC11 PF12861.7 OAG40050.1 - 0.00011 22.1 1.5 0.00037 20.5 1.0 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 OAG40050.1 - 0.00026 21.2 6.4 0.00062 20.0 6.4 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 OAG40050.1 - 0.0056 16.5 2.6 0.91 9.4 0.5 2.5 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 PhnA_Zn_Ribbon PF08274.12 OAG40050.1 - 0.014 15.4 1.6 0.72 9.9 0.1 2.5 2 0 0 2 2 2 0 PhnA Zinc-Ribbon zf-RING_UBOX PF13445.6 OAG40050.1 - 0.089 12.8 6.0 0.18 11.9 6.0 1.6 1 0 0 1 1 1 0 RING-type zinc-finger RINGv PF12906.7 OAG40050.1 - 0.15 12.2 6.0 0.33 11.1 6.0 1.6 1 0 0 1 1 1 0 RING-variant domain Zf_RING PF16744.5 OAG40050.1 - 0.17 12.0 2.6 0.46 10.6 2.6 1.7 1 0 0 1 1 1 0 KIAA1045 RING finger zf-Di19 PF05605.12 OAG40050.1 - 0.17 12.2 3.5 12 6.3 1.1 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Rad50_zn_hook PF04423.14 OAG40050.1 - 0.18 11.7 7.2 8.5 6.3 0.2 4.4 3 1 1 4 4 4 0 Rad50 zinc hook motif zf-RING_5 PF14634.6 OAG40050.1 - 0.31 11.0 5.1 0.65 10.0 5.1 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.25 OAG40050.1 - 0.53 10.2 6.5 1.1 9.1 6.5 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 OAG40050.1 - 0.69 9.8 5.0 1.5 8.8 5.0 1.6 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_3 PF13920.6 OAG40050.1 - 1.2 9.0 6.2 4.5 7.2 6.2 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.6 OAG40050.1 - 2 8.4 5.1 4 7.5 2.7 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-C3HC4_2 PF13923.6 OAG40050.1 - 3.4 7.6 10.9 14 5.6 10.9 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-MIZ PF02891.20 OAG40050.1 - 5.4 6.8 7.8 8.7 6.2 3.8 2.6 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger Ion_trans_2 PF07885.16 OAG40053.1 - 7.3e-29 99.6 25.1 2.9e-15 56.0 4.6 3.3 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.31 OAG40053.1 - 0.0014 17.9 15.8 0.0094 15.2 3.1 2.5 2 0 0 2 2 2 2 Ion transport protein DBP PF12361.8 OAG40054.1 - 0.18 11.6 3.2 0.63 9.8 1.2 2.0 2 0 0 2 2 2 0 Duffy-antigen binding protein UL42 PF17638.2 OAG40055.1 - 0.094 12.7 3.5 0.17 11.9 3.5 1.4 1 0 0 1 1 1 0 HCMV UL42 ATP-synt PF00231.19 OAG40057.1 - 8.9e-80 268.4 1.8 1.1e-79 268.1 1.8 1.0 1 0 0 1 1 1 1 ATP synthase Topoisom_I_N PF02919.15 OAG40058.1 - 4.4e-97 323.7 3.5 4.4e-97 323.7 3.5 4.1 4 0 0 4 4 4 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.20 OAG40058.1 - 8.6e-97 322.9 5.6 8.6e-97 322.9 5.6 2.4 3 1 0 3 3 3 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.6 OAG40058.1 - 2.4e-33 113.9 1.2 9.7e-33 111.9 1.2 2.2 1 0 0 1 1 1 1 C-terminal topoisomerase domain CBFB_NFYA PF02045.15 OAG40059.1 - 1.1e-28 99.6 4.6 2.4e-28 98.5 4.6 1.6 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Hus1 PF04005.12 OAG40059.1 - 0.039 13.1 0.0 0.06 12.4 0.0 1.2 1 0 0 1 1 1 0 Hus1-like protein TFIIA PF03153.13 OAG40059.1 - 0.15 12.0 20.2 0.19 11.7 20.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit UBA2_C PF16195.5 OAG40059.1 - 0.53 11.0 8.5 0.13 13.0 4.4 2.2 2 0 0 2 2 2 0 SUMO-activating enzyme subunit 2 C-terminus DUF3818 PF12825.7 OAG40060.1 - 7.2e-131 436.2 0.4 1.3e-130 435.4 0.4 1.5 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 OAG40060.1 - 6.8e-39 132.8 1.4 1.6e-38 131.6 1.4 1.7 1 0 0 1 1 1 1 PX-associated PX PF00787.24 OAG40060.1 - 3.9e-15 55.8 0.4 1.4e-14 54.0 0.0 2.2 2 0 0 2 2 2 1 PX domain RE_Bpu10I PF09549.10 OAG40060.1 - 0.039 13.5 0.2 0.099 12.2 0.2 1.6 1 0 0 1 1 1 0 Bpu10I restriction endonuclease RRN3 PF05327.11 OAG40060.1 - 2.1 6.8 6.8 0.59 8.6 0.2 2.4 1 1 1 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 ADH_zinc_N PF00107.26 OAG40061.1 - 5.4e-10 39.4 0.0 1.1e-09 38.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAG40061.1 - 0.026 15.6 0.0 0.046 14.8 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase PEP_mutase PF13714.6 OAG40061.1 - 0.041 13.3 0.0 0.061 12.8 0.0 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate phosphomutase S4 PF01479.25 OAG40062.1 - 2.7e-10 39.8 0.3 6.6e-10 38.5 0.1 1.8 2 0 0 2 2 2 1 S4 domain Ribosomal_S4 PF00163.19 OAG40062.1 - 5.5e-09 36.8 0.2 9.4e-09 36.1 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain MFS_1 PF07690.16 OAG40064.1 - 1.6e-35 122.6 50.8 2.9e-35 121.8 50.8 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG40066.1 - 3.5e-90 303.0 16.3 4.3e-90 302.7 16.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG40066.1 - 2e-15 56.6 34.6 4.4e-14 52.2 24.7 3.0 1 1 2 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.6 OAG40066.1 - 2.1e-05 23.3 16.2 0.0021 16.7 4.0 2.6 3 0 0 3 3 3 2 MFS/sugar transport protein Romo1 PF10247.9 OAG40066.1 - 7.2 7.1 7.7 0.55 10.6 0.3 2.8 3 0 0 3 3 3 0 Reactive mitochondrial oxygen species modulator 1 Alpha-amylase PF00128.24 OAG40067.1 - 2.4e-112 375.9 0.0 3.5e-112 375.3 0.0 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Amidase PF01425.21 OAG40068.1 - 7.1e-73 246.1 0.0 1.4e-72 245.1 0.0 1.5 1 1 0 1 1 1 1 Amidase Transp_cyt_pur PF02133.15 OAG40069.1 - 1.2e-89 301.2 41.6 1.4e-89 301.0 41.6 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Amdase PF17645.1 OAG40070.1 - 4.3e-14 52.7 0.0 5.1e-14 52.4 0.0 1.1 1 0 0 1 1 1 1 Arylmalonate decarboxylase Fungal_trans PF04082.18 OAG40071.1 - 8.3e-17 61.1 0.0 1.1e-16 60.6 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain SPC25 PF06703.11 OAG40072.1 - 1.4e-51 174.5 0.2 1.7e-51 174.2 0.2 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) CST-I PF06002.12 OAG40072.1 - 0.086 12.6 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Alpha-2,3-sialyltransferase (CST-I) Adaptin_N PF01602.20 OAG40073.1 - 3.9e-117 392.0 0.1 5.2e-117 391.6 0.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 OAG40073.1 - 2.9e-55 186.5 3.3 5.8e-55 185.6 3.3 1.5 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 OAG40073.1 - 4.7e-29 100.8 0.1 1.8e-28 99.0 0.1 2.0 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 OAG40073.1 - 3.7e-20 72.1 2.6 2.6e-12 47.0 0.0 5.7 4 1 2 6 6 6 3 HEAT repeats Cnd1 PF12717.7 OAG40073.1 - 1.5e-09 38.1 7.8 0.0073 16.4 0.1 4.7 4 1 0 4 4 4 3 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 OAG40073.1 - 0.00036 20.6 11.0 0.26 11.7 0.1 6.3 7 0 0 7 7 7 1 HEAT repeat HEAT_PBS PF03130.16 OAG40073.1 - 0.00069 20.1 1.4 5.3 8.0 0.0 4.3 4 0 0 4 4 4 2 PBS lyase HEAT-like repeat HEAT_EZ PF13513.6 OAG40073.1 - 0.011 16.2 2.1 0.098 13.2 0.4 3.0 2 0 0 2 2 2 0 HEAT-like repeat Arm PF00514.23 OAG40073.1 - 0.016 15.2 0.0 5.7 7.1 0.0 4.3 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat CLASP_N PF12348.8 OAG40073.1 - 0.092 12.3 2.4 1.9 8.0 0.1 3.1 4 0 0 4 4 4 0 CLASP N terminal Fes1 PF08609.10 OAG40073.1 - 0.22 12.4 0.8 6.2 7.8 0.1 2.7 2 0 0 2 2 2 0 Nucleotide exchange factor Fes1 Phosducin PF02114.16 OAG40074.1 - 3.6e-11 42.5 0.2 7.2e-11 41.5 0.2 1.5 1 1 0 1 1 1 1 Phosducin RPOL_N PF14700.6 OAG40074.1 - 0.087 12.2 0.2 0.38 10.1 0.2 1.7 1 1 0 1 1 1 0 DNA-directed RNA polymerase N-terminal bZIP_1 PF00170.21 OAG40075.1 - 1.6e-09 37.7 10.1 3.1e-09 36.8 10.1 1.4 1 0 0 1 1 1 1 bZIP transcription factor PAP1 PF08601.10 OAG40075.1 - 9.8e-08 32.1 0.0 9.8e-08 32.1 0.0 2.4 2 1 0 2 2 2 1 Transcription factor PAP1 bZIP_Maf PF03131.17 OAG40075.1 - 7.5e-07 29.6 3.2 1.3e-06 28.9 3.2 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_2 PF07716.15 OAG40075.1 - 0.0052 16.9 12.6 0.0074 16.3 12.0 1.5 1 1 0 1 1 1 1 Basic region leucine zipper SHE3 PF17078.5 OAG40075.1 - 0.019 14.7 3.7 0.027 14.2 3.7 1.2 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 DUF2514 PF10721.9 OAG40075.1 - 0.02 14.9 3.8 0.038 14.0 3.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) TMF_TATA_bd PF12325.8 OAG40075.1 - 0.028 14.6 3.8 0.054 13.7 3.8 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding V_ATPase_I PF01496.19 OAG40075.1 - 0.038 11.9 1.5 0.05 11.5 1.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ADIP PF11559.8 OAG40075.1 - 0.061 13.4 8.6 0.1 12.7 8.6 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding NRBF2 PF08961.10 OAG40075.1 - 0.12 11.9 5.5 0.18 11.4 5.4 1.3 1 1 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator YabA PF06156.13 OAG40075.1 - 0.18 12.5 0.7 0.33 11.6 0.7 1.5 1 0 0 1 1 1 0 Initiation control protein YabA APG6_N PF17675.1 OAG40075.1 - 0.66 10.5 7.1 1 9.9 7.1 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region Aldo_ket_red PF00248.21 OAG40076.1 - 1e-28 100.4 0.0 1.2e-26 93.6 0.0 2.1 1 1 0 1 1 1 1 Aldo/keto reductase family SNF2_N PF00176.23 OAG40078.1 - 7.4e-65 219.0 0.0 1.1e-64 218.4 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OAG40078.1 - 1.4e-11 44.7 0.0 4.2e-11 43.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 OAG40078.1 - 4.9e-06 26.4 0.0 1.1e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 OAG40078.1 - 2e-05 24.7 0.0 6.6e-05 23.0 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Prok-RING_4 PF14447.6 OAG40078.1 - 0.00038 20.2 5.5 0.0011 18.8 5.4 1.8 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 OAG40078.1 - 0.0037 17.2 5.4 0.0073 16.2 5.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 OAG40078.1 - 3.3 7.7 5.0 0.89 9.5 1.3 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Zn-ribbon_8 PF09723.10 OAG40078.1 - 3.8 7.7 5.2 14 5.9 2.8 2.6 2 0 0 2 2 2 0 Zinc ribbon domain Glyco_hydro_63 PF03200.16 OAG40079.1 - 2.4e-07 29.9 8.9 7.6e-06 25.0 0.7 4.3 4 1 0 4 4 4 2 Glycosyl hydrolase family 63 C-terminal domain TTSSLRR PF12468.8 OAG40079.1 - 0.043 14.1 0.4 0.14 12.4 0.4 2.0 1 1 0 1 1 1 0 Type III secretion system leucine rich repeat protein UDPGT PF00201.18 OAG40079.1 - 0.076 11.8 0.2 0.15 10.8 0.0 1.4 2 0 0 2 2 2 0 UDP-glucoronosyl and UDP-glucosyl transferase V-ATPase_G_2 PF16999.5 OAG40080.1 - 0.63 10.5 2.7 0.3 11.5 0.3 1.7 2 0 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit TetR_C_28 PF17937.1 OAG40080.1 - 1.9 9.0 4.8 7.1 7.2 0.1 2.9 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain OSCP PF00213.18 OAG40081.1 - 4e-46 157.3 2.0 4.6e-46 157.1 2.0 1.0 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit AdoHcyase PF05221.17 OAG40083.1 - 1.2e-128 428.4 0.0 1e-72 244.8 0.1 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 OAG40083.1 - 2.5e-84 281.2 4.4 4.1e-84 280.5 4.4 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 OAG40083.1 - 2.4e-08 33.5 0.2 4.6e-08 32.6 0.2 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 OAG40083.1 - 0.0012 18.4 0.3 0.0021 17.6 0.3 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 OAG40083.1 - 0.0022 18.2 0.1 0.0053 17.0 0.1 1.6 1 0 0 1 1 1 1 TrkA-N domain Oxidored_nitro PF00148.19 OAG40083.1 - 0.016 13.9 0.1 0.26 10.0 0.0 2.1 2 0 0 2 2 2 0 Nitrogenase component 1 type Oxidoreductase ELFV_dehydrog PF00208.21 OAG40083.1 - 0.047 13.4 0.9 0.085 12.6 0.9 1.5 1 1 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 3HCDH_N PF02737.18 OAG40083.1 - 0.15 11.9 0.5 0.26 11.2 0.5 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AKAP7_NLS PF10469.9 OAG40085.1 - 4.2e-18 66.0 0.0 2.4e-17 63.5 0.0 2.0 1 1 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain LigT_PEase PF02834.16 OAG40085.1 - 2.3e-05 24.5 0.7 1.8 8.8 0.0 4.2 4 1 1 5 5 5 2 LigT like Phosphoesterase 2_5_RNA_ligase2 PF13563.6 OAG40085.1 - 8.2e-05 22.6 0.8 0.0011 19.0 0.1 2.4 3 0 0 3 3 3 1 2'-5' RNA ligase superfamily SipA_VBS PF17985.1 OAG40085.1 - 0.11 12.4 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 SipA vinculin binding site zf-CSL PF05207.13 OAG40086.1 - 1.8e-21 75.6 0.2 3.5e-21 74.7 0.2 1.5 1 0 0 1 1 1 1 CSL zinc finger Ribosomal_L15e PF00827.17 OAG40087.1 - 5.6e-90 300.2 9.8 6.9e-90 299.9 9.8 1.0 1 0 0 1 1 1 1 Ribosomal L15 PSP1 PF04468.12 OAG40089.1 - 1.2e-27 96.0 3.9 2.2e-27 95.1 3.9 1.5 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Nfu_N PF08712.11 OAG40090.1 - 3.4e-30 103.9 0.0 1.4e-29 101.9 0.0 1.9 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 OAG40090.1 - 9.2e-27 93.0 0.1 1.5e-26 92.3 0.1 1.3 1 0 0 1 1 1 1 NifU-like domain RasGEF PF00617.19 OAG40092.1 - 2.5e-43 148.3 0.0 5.2e-43 147.3 0.0 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 OAG40092.1 - 2.8e-10 40.4 0.0 8e-10 38.9 0.0 1.8 1 0 0 1 1 1 1 RasGEF N-terminal motif Ras PF00071.22 OAG40092.1 - 0.00029 20.5 0.0 0.01 15.5 0.0 2.8 3 0 0 3 3 3 1 Ras family G-alpha PF00503.20 OAG40092.1 - 0.055 12.6 0.0 0.1 11.7 0.0 1.4 1 0 0 1 1 1 0 G-protein alpha subunit MIP PF00230.20 OAG40093.1 - 1.5e-46 159.0 16.5 1.8e-46 158.7 16.5 1.0 1 0 0 1 1 1 1 Major intrinsic protein FA_desaturase PF00487.24 OAG40093.1 - 0.0053 16.6 4.8 0.0053 16.6 4.8 2.1 1 1 1 2 2 2 1 Fatty acid desaturase Kinesin PF00225.23 OAG40094.1 - 3e-108 361.7 0.0 6.3e-108 360.6 0.0 1.5 1 0 0 1 1 1 1 Kinesin motor domain Kinesin_assoc PF16183.5 OAG40094.1 - 2.3e-39 135.4 6.8 1e-31 110.5 0.1 2.9 2 1 1 3 3 3 2 Kinesin-associated DUF3694 PF12473.8 OAG40094.1 - 1.1e-38 133.2 0.0 3e-38 131.9 0.0 1.8 1 0 0 1 1 1 1 Kinesin protein Microtub_bd PF16796.5 OAG40094.1 - 2.5e-22 79.4 0.0 7.3e-22 77.9 0.0 1.9 1 0 0 1 1 1 1 Microtubule binding FHA PF00498.26 OAG40094.1 - 6.1e-06 26.5 2.3 2.2e-05 24.7 0.2 3.2 4 0 0 4 4 4 1 FHA domain KIF1B PF12423.8 OAG40094.1 - 8.6e-05 22.9 0.5 0.0003 21.2 0.5 2.0 1 0 0 1 1 1 1 Kinesin protein 1B Yop-YscD_cpl PF16697.5 OAG40094.1 - 0.00013 22.2 0.0 0.00042 20.6 0.0 1.9 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain PH PF00169.29 OAG40094.1 - 0.076 13.5 0.0 0.32 11.5 0.0 2.1 1 1 0 1 1 1 0 PH domain UPF0242 PF06785.11 OAG40094.1 - 0.49 10.5 16.0 0.91 9.6 2.2 2.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus zf-GRF PF06839.12 OAG40095.1 - 1.7e-08 34.4 8.1 3.2e-08 33.5 8.1 1.5 1 0 0 1 1 1 1 GRF zinc finger PKcGMP_CC PF16808.5 OAG40095.1 - 0.026 14.4 0.2 0.079 12.8 0.2 1.8 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase FAA_hydrolase PF01557.18 OAG40096.1 - 2.5e-56 190.8 0.0 3.2e-56 190.4 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Glyoxalase PF00903.25 OAG40097.1 - 2.6e-13 50.3 0.0 3.9e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 OAG40097.1 - 0.09 13.6 0.0 0.32 11.8 0.0 1.9 2 1 0 2 2 2 0 Glyoxalase-like domain DUF2339 PF10101.9 OAG40099.1 - 1.7e-05 23.6 3.7 2.2e-05 23.3 3.7 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2339) LSR PF05624.14 OAG40099.1 - 0.033 14.2 0.7 0.083 12.9 0.7 1.7 1 0 0 1 1 1 0 Lipolysis stimulated receptor (LSR) Phage_holin_3_6 PF07332.11 OAG40099.1 - 0.1 12.7 10.1 4.3 7.4 8.4 2.3 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III TctB PF07331.11 OAG40099.1 - 1.3 9.3 12.1 3 8.1 12.3 1.5 1 1 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family DUF4131 PF13567.6 OAG40099.1 - 6.6 6.4 10.3 17 5.0 7.0 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF4131) Peptidase_M64 PF09471.10 OAG40100.1 - 0.055 13.0 0.0 0.08 12.5 0.0 1.2 1 0 0 1 1 1 0 IgA Peptidase M64 SID-1_RNA_chan PF13965.6 OAG40101.1 - 0.0036 15.8 0.0 0.0052 15.3 0.0 1.1 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 PCI PF01399.27 OAG40101.1 - 0.036 14.6 0.0 20 5.7 0.0 2.8 2 0 0 2 2 2 0 PCI domain TPR_2 PF07719.17 OAG40101.1 - 0.079 13.1 0.2 0.19 11.9 0.2 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat HEAT_PBS PF03130.16 OAG40101.1 - 0.08 13.7 0.0 0.41 11.4 0.0 2.3 2 0 0 2 2 2 0 PBS lyase HEAT-like repeat ANAPC3 PF12895.7 OAG40101.1 - 1.4 9.2 5.6 0.53 10.5 0.8 2.5 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Sof1 PF04158.14 OAG40102.1 - 2.5e-32 111.0 14.3 4e-32 110.3 14.3 1.3 1 0 0 1 1 1 1 Sof1-like domain WD40 PF00400.32 OAG40102.1 - 7.7e-31 105.7 7.7 4.3e-06 27.3 0.1 7.0 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG40102.1 - 9.5e-10 38.7 0.2 0.0061 16.8 0.1 4.4 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OAG40102.1 - 0.0003 19.8 0.0 0.046 12.7 0.0 2.7 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 OAG40102.1 - 0.0021 16.5 0.0 0.036 12.4 0.0 2.3 1 1 0 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz RPN6_N PF18055.1 OAG40103.1 - 4.9e-45 152.7 3.8 9.5e-45 151.7 1.1 2.6 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 OAG40103.1 - 1.1e-20 74.1 0.9 2.8e-20 72.8 0.3 2.1 2 0 0 2 2 2 1 PCI domain RPN6_C_helix PF18503.1 OAG40103.1 - 9.3e-12 44.5 0.5 2.3e-11 43.2 0.5 1.8 1 0 0 1 1 1 1 26S proteasome subunit RPN6 C-terminal helix domain TPR_MalT PF17874.1 OAG40103.1 - 5.2e-05 22.8 8.2 0.002 17.6 1.8 3.1 2 1 1 3 3 3 2 MalT-like TPR region DDRGK PF09756.9 OAG40103.1 - 0.00015 21.4 0.4 0.00034 20.3 0.4 1.5 1 0 0 1 1 1 1 DDRGK domain TPR_7 PF13176.6 OAG40103.1 - 0.014 15.3 3.9 2.5 8.3 0.1 4.6 3 1 0 3 3 3 0 Tetratricopeptide repeat ABC_membrane_2 PF06472.15 OAG40103.1 - 0.016 14.7 0.1 0.028 13.8 0.1 1.3 1 0 0 1 1 1 0 ABC transporter transmembrane region 2 TPPII_N PF12583.8 OAG40103.1 - 0.02 15.5 0.0 0.056 14.0 0.0 1.7 1 0 0 1 1 1 0 Tripeptidyl peptidase II N terminal HTH_Crp_2 PF13545.6 OAG40103.1 - 0.031 14.3 0.0 2 8.5 0.0 2.7 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain DUF4456 PF14644.6 OAG40103.1 - 0.056 13.1 4.4 0.41 10.3 0.6 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4456) SbsC_C PF18058.1 OAG40103.1 - 0.078 13.2 0.2 0.078 13.2 0.2 2.4 2 0 0 2 2 2 0 SbsC C-terminal domain TPR_12 PF13424.6 OAG40103.1 - 0.11 12.7 18.6 0.31 11.3 1.8 5.3 4 2 2 6 6 5 0 Tetratricopeptide repeat DUF4398 PF14346.6 OAG40103.1 - 3.7 8.2 11.3 1.1 10.0 0.6 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4398) TPR_19 PF14559.6 OAG40103.1 - 6.5 7.3 7.5 2.7 8.6 0.2 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 OAG40103.1 - 6.9 6.7 7.2 32 4.5 0.0 4.0 4 1 1 5 5 4 0 Tetratricopeptide repeat EF-hand_6 PF13405.6 OAG40104.1 - 4.2e-25 85.5 4.8 7.9e-07 28.5 0.1 5.2 5 0 0 5 5 5 4 EF-hand domain EF-hand_7 PF13499.6 OAG40104.1 - 5.9e-25 87.5 8.2 6.4e-16 58.6 0.6 3.1 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 OAG40104.1 - 9e-25 84.3 12.1 3.4e-08 32.5 0.1 4.8 5 0 0 5 5 5 3 EF hand EF-hand_5 PF13202.6 OAG40104.1 - 3e-17 61.2 11.9 4.7e-05 22.7 0.1 4.8 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.6 OAG40104.1 - 3e-14 52.6 14.3 1.2e-05 25.1 0.9 4.1 3 2 1 4 4 4 3 EF-hand domain pair EF-hand_4 PF12763.7 OAG40104.1 - 1.8e-08 34.2 6.1 0.0021 18.0 0.1 3.9 1 1 2 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 OAG40104.1 - 9.7e-05 22.6 0.6 0.0035 17.6 0.1 3.0 2 1 1 3 3 3 1 EF-hand domain SPARC_Ca_bdg PF10591.9 OAG40104.1 - 0.00088 19.6 2.5 0.97 9.8 0.2 3.1 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 OAG40104.1 - 0.0039 17.0 2.0 0.88 9.5 0.0 3.6 5 0 0 5 5 5 1 EF hand DUF1679 PF07914.11 OAG40104.1 - 0.023 13.5 0.5 1.9 7.2 0.1 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1679) Staphylokinase PF02821.16 OAG40104.1 - 0.029 14.8 0.0 3.7 8.0 0.0 2.5 1 1 1 2 2 2 0 Staphylokinase/Streptokinase family EF-hand_14 PF17959.1 OAG40104.1 - 0.3 11.5 1.6 12 6.3 0.0 3.4 4 0 0 4 4 4 0 EF-hand domain EMP70 PF02990.16 OAG40105.1 - 3.8e-198 659.4 0.1 5e-198 659.0 0.1 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 HATPase_c PF02518.26 OAG40106.1 - 1e-22 80.8 0.3 3e-22 79.2 0.1 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 OAG40106.1 - 1.6e-20 73.3 0.0 4.3e-20 72.0 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 OAG40106.1 - 8.8e-16 57.7 0.0 2.1e-15 56.5 0.0 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.12 OAG40106.1 - 1.3e-10 41.4 0.6 7.4e-05 23.0 0.0 3.6 3 0 0 3 3 3 3 PAS fold PAS_4 PF08448.10 OAG40106.1 - 0.002 18.4 0.0 0.074 13.3 0.0 2.8 3 0 0 3 3 3 1 PAS fold PAS PF00989.25 OAG40106.1 - 0.14 12.2 0.0 0.75 9.8 0.0 2.3 3 0 0 3 3 3 0 PAS fold KxDL PF10241.9 OAG40107.1 - 5.3e-30 103.5 3.1 8.3e-30 102.9 3.1 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein SNRNP27 PF08648.12 OAG40108.1 - 0.01 15.9 0.1 0.018 15.1 0.1 1.4 1 0 0 1 1 1 0 U4/U6.U5 small nuclear ribonucleoproteins DUF4551 PF15087.6 OAG40108.1 - 0.048 12.5 0.7 0.055 12.3 0.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) ADH_zinc_N PF00107.26 OAG40109.1 - 6.6e-26 90.8 0.0 1.1e-25 90.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAG40109.1 - 1.9e-10 41.9 0.0 6.5e-10 40.2 0.0 1.9 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG40109.1 - 2.6e-07 30.5 0.0 1.2e-06 28.3 0.0 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ACP_syn_III_C PF08541.10 OAG40109.1 - 0.0068 16.6 0.6 0.11 12.7 0.2 2.5 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal AlaDh_PNT_C PF01262.21 OAG40109.1 - 0.019 14.3 0.2 0.029 13.7 0.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 OAG40109.1 - 0.092 12.1 0.1 0.15 11.4 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain adh_short PF00106.25 OAG40109.1 - 0.15 11.5 0.5 0.29 10.6 0.5 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Pyr_redox_3 PF13738.6 OAG40110.1 - 2e-10 40.4 0.0 2.6e-07 30.2 0.0 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAG40110.1 - 1.8e-07 30.7 0.0 0.01 15.1 0.0 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 OAG40110.1 - 6.9e-07 28.1 0.0 1.7e-05 23.5 0.0 2.4 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OAG40110.1 - 2.9e-05 24.2 0.0 7.8e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.20 OAG40110.1 - 0.0004 20.5 0.0 0.47 10.5 0.0 2.5 2 1 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase K_oxygenase PF13434.6 OAG40110.1 - 0.00049 19.4 0.0 0.13 11.4 0.0 2.6 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.24 OAG40110.1 - 0.00069 18.8 0.0 0.0011 18.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAG40110.1 - 0.00087 19.0 0.9 0.036 13.7 0.3 2.9 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 OAG40110.1 - 0.0097 15.2 0.3 0.024 13.9 0.3 1.7 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.6 OAG40110.1 - 0.089 12.8 0.3 7.5 6.5 0.1 3.5 4 0 0 4 4 4 0 FAD-NAD(P)-binding F420_oxidored PF03807.17 OAG40110.1 - 0.12 13.0 2.0 18 6.0 0.0 2.9 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 OAG40110.1 - 0.29 10.5 0.0 0.29 10.5 0.0 1.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DSPc PF00782.20 OAG40111.1 - 1.4e-18 66.9 0.0 2.9e-17 62.7 0.0 2.2 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 OAG40111.1 - 0.0076 15.8 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DUF4060 PF13269.6 OAG40111.1 - 0.039 14.0 0.2 0.96 9.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4060) FMN_dh PF01070.18 OAG40111.1 - 0.085 11.9 0.6 0.12 11.4 0.6 1.1 1 0 0 1 1 1 0 FMN-dependent dehydrogenase COesterase PF00135.28 OAG40112.1 - 9.5e-77 259.0 0.1 3e-68 230.9 0.1 2.2 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 OAG40112.1 - 7.7e-05 22.6 0.1 0.00021 21.2 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold TFR_dimer PF04253.15 OAG40113.1 - 5.3e-33 113.7 0.0 9.6e-33 112.9 0.0 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 OAG40113.1 - 1.3e-19 70.7 0.0 3.2e-19 69.4 0.0 1.7 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 OAG40113.1 - 5e-12 45.7 0.1 2.2e-11 43.6 0.1 2.0 1 1 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 OAG40113.1 - 0.029 14.1 0.0 0.072 12.8 0.0 1.7 1 1 0 1 1 1 0 Peptidase family M20/M25/M40 PRP3 PF08572.10 OAG40114.1 - 9.9e-73 244.6 5.0 2.1e-72 243.5 5.0 1.6 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 OAG40114.1 - 1.1e-44 152.1 1.3 1.1e-44 152.1 1.3 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) BLUF PF04940.12 OAG40114.1 - 0.11 12.6 0.4 2.5 8.3 0.0 2.6 1 1 1 2 2 2 0 Sensors of blue-light using FAD SF1-HH PF16275.5 OAG40114.1 - 0.94 9.8 5.6 1.4 9.3 0.4 3.6 4 0 0 4 4 4 0 Splicing factor 1 helix-hairpin domain Fungal_trans PF04082.18 OAG40115.1 - 0.079 12.0 0.2 10 5.1 0.0 2.3 2 0 0 2 2 2 0 Fungal specific transcription factor domain MFS_1 PF07690.16 OAG40116.1 - 2.5e-32 112.2 40.3 2.5e-32 112.2 40.3 1.9 1 1 0 2 2 2 1 Major Facilitator Superfamily DUF1218 PF06749.12 OAG40116.1 - 0.031 14.8 2.1 0.031 14.8 2.1 3.8 4 1 0 4 4 4 0 Protein of unknown function (DUF1218) Trp_oprn_chp PF09534.10 OAG40116.1 - 0.49 10.2 2.2 3.3 7.5 0.0 2.9 3 0 0 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Amidohydro_1 PF01979.20 OAG40117.1 - 7.7e-45 153.7 0.0 9.3e-45 153.4 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 OAG40117.1 - 5.7e-22 78.8 2.4 3.9e-15 56.3 0.1 2.3 2 0 0 2 2 2 2 Amidohydrolase family Fungal_trans PF04082.18 OAG40118.1 - 4.7e-15 55.3 0.5 7.5e-15 54.7 0.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pro_dh PF01619.18 OAG40119.1 - 8.5e-61 206.1 0.0 1.7e-60 205.1 0.0 1.5 1 1 0 1 1 1 1 Proline dehydrogenase HTH_11 PF08279.12 OAG40119.1 - 0.14 12.1 0.1 0.93 9.5 0.1 2.3 2 0 0 2 2 2 0 HTH domain Aldedh PF00171.22 OAG40120.1 - 4.3e-104 348.6 0.0 5.8e-104 348.2 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family 2-oxoacid_dh PF00198.23 OAG40121.1 - 4.6e-79 265.1 0.1 6.9e-79 264.6 0.1 1.3 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 OAG40121.1 - 8.2e-18 64.0 3.4 1.5e-17 63.2 3.4 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme HlyD_3 PF13437.6 OAG40121.1 - 0.016 15.9 0.6 1 10.1 0.1 2.6 1 1 1 2 2 2 0 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 OAG40121.1 - 0.02 14.7 0.2 0.44 10.4 0.1 2.5 1 1 1 2 2 2 0 Biotin-lipoyl like DUF3614 PF12267.8 OAG40121.1 - 0.081 13.4 0.2 0.37 11.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3614) GCV_H PF01597.19 OAG40121.1 - 0.082 12.8 0.5 0.19 11.6 0.5 1.7 1 0 0 1 1 1 0 Glycine cleavage H-protein RnfC_N PF13375.6 OAG40121.1 - 0.14 12.1 0.3 0.97 9.4 0.3 2.3 1 1 1 2 2 2 0 RnfC Barrel sandwich hybrid domain PYNP_C PF07831.13 OAG40121.1 - 0.17 11.5 0.4 2.9 7.6 0.1 2.4 1 1 1 2 2 2 0 Pyrimidine nucleoside phosphorylase C-terminal domain Transket_pyr PF02779.24 OAG40122.1 - 4e-58 196.0 0.0 1.4e-57 194.3 0.0 1.8 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 OAG40122.1 - 6.6e-53 179.6 0.0 9.8e-53 179.0 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 OAG40122.1 - 2.9e-32 111.5 0.0 5.9e-32 110.5 0.0 1.5 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 OAG40122.1 - 1.1e-12 47.3 0.6 2.8e-12 46.0 0.6 1.7 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus DUF4403 PF14356.6 OAG40122.1 - 0.0038 16.0 0.1 0.0058 15.3 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4403) adh_short PF00106.25 OAG40123.1 - 4.2e-28 98.1 0.0 6.1e-28 97.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG40123.1 - 2.2e-24 86.3 0.0 6e-24 84.9 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 OAG40123.1 - 0.026 14.0 0.0 0.077 12.5 0.0 1.7 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family KR PF08659.10 OAG40123.1 - 0.092 12.7 0.1 2.5 8.0 0.1 2.2 1 1 0 1 1 1 0 KR domain GST_N_3 PF13417.6 OAG40124.1 - 4.5e-16 59.0 0.0 1e-15 57.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 OAG40124.1 - 2.2e-15 56.8 0.0 3.7e-15 56.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OAG40124.1 - 2.5e-12 46.8 0.1 4.1e-12 46.2 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 OAG40124.1 - 1.5e-11 44.4 0.0 3.3e-11 43.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 OAG40124.1 - 2.9e-07 30.6 0.0 4.6e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OAG40124.1 - 0.00051 20.0 1.8 0.00088 19.3 0.1 2.2 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain Sugar_tr PF00083.24 OAG40125.1 - 6.3e-85 285.7 20.4 7.7e-85 285.4 20.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG40125.1 - 1.2e-24 86.9 51.3 4.8e-24 85.0 27.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 OAG40125.1 - 0.00042 18.9 2.8 0.00042 18.9 2.8 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) PUCC PF03209.15 OAG40125.1 - 0.0023 17.0 14.7 0.0023 17.0 14.7 2.3 3 0 0 3 3 3 1 PUCC protein p450 PF00067.22 OAG40126.1 - 1.6e-65 221.6 0.0 2.1e-65 221.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.25 OAG40127.1 - 1.3e-39 135.7 0.5 1.6e-39 135.4 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG40127.1 - 3e-26 92.4 0.1 3.4e-26 92.3 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG40127.1 - 3e-10 40.3 0.3 4.5e-10 39.7 0.3 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG40127.1 - 7.2e-06 25.6 0.4 0.0083 15.6 0.1 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 OAG40127.1 - 0.00087 18.7 0.0 0.0011 18.4 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.6 OAG40127.1 - 0.0025 17.7 0.2 0.0033 17.3 0.2 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Fungal_trans PF04082.18 OAG40128.1 - 8.1e-20 71.0 0.1 1.4e-19 70.2 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG40128.1 - 7.9e-06 25.9 1.5 1.8e-05 24.8 1.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short_C2 PF13561.6 OAG40129.1 - 6e-51 173.2 0.0 7.1e-51 173.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG40129.1 - 1.3e-41 142.2 0.0 1.6e-41 141.9 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG40129.1 - 4.7e-13 49.4 0.0 6.6e-13 49.0 0.0 1.1 1 0 0 1 1 1 1 KR domain MFS_1 PF07690.16 OAG40130.1 - 3.9e-37 128.0 11.9 3.9e-37 128.0 11.9 1.9 1 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG40130.1 - 5.7e-17 61.7 0.3 5.7e-17 61.7 0.3 3.2 3 2 1 4 4 4 1 Sugar (and other) transporter TRI12 PF06609.13 OAG40130.1 - 0.00079 18.0 1.6 0.00079 18.0 1.6 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) FMO-like PF00743.19 OAG40131.1 - 3e-15 55.7 0.5 4.1e-14 51.9 0.5 2.4 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 OAG40131.1 - 5.1e-08 32.4 0.4 7e-06 25.4 0.0 2.9 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 OAG40131.1 - 1.2e-07 31.9 0.1 2.8e-07 30.7 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 OAG40131.1 - 9.5e-06 25.7 0.0 0.0078 16.2 0.0 2.6 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 OAG40131.1 - 1.7e-05 24.2 0.3 0.00042 19.7 0.0 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase MCRA PF06100.11 OAG40131.1 - 0.0012 17.8 0.1 0.0017 17.2 0.1 1.2 1 0 0 1 1 1 1 MCRA family Pyr_redox_2 PF07992.14 OAG40131.1 - 0.0018 17.5 0.0 0.12 11.6 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 OAG40131.1 - 0.023 15.1 0.0 1.1 9.7 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding DUF498 PF04430.14 OAG40131.1 - 0.028 14.5 0.0 1.3 9.1 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF498/DUF598) DAO PF01266.24 OAG40131.1 - 0.13 11.8 0.1 1 8.8 0.0 2.5 2 1 1 3 3 3 0 FAD dependent oxidoreductase FCH PF00611.23 OAG40131.1 - 0.66 10.3 2.7 2.1 8.7 0.7 2.6 2 1 1 3 3 3 0 Fes/CIP4, and EFC/F-BAR homology domain CoA_transf_3 PF02515.17 OAG40132.1 - 1.4e-37 129.7 0.1 1.8e-34 119.5 0.1 2.8 2 1 0 2 2 2 2 CoA-transferase family III DLH PF01738.18 OAG40132.1 - 2.2e-22 79.7 0.0 4.5e-22 78.7 0.0 1.5 1 0 0 1 1 1 1 Dienelactone hydrolase family MARVEL PF01284.23 OAG40133.1 - 0.1 12.6 18.2 0.21 11.6 12.8 2.1 1 1 0 2 2 2 0 Membrane-associating domain DUF3789 PF12664.7 OAG40133.1 - 0.32 10.7 2.1 0.61 9.8 2.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3789) RNA_pol_Rpb1_5 PF04998.17 OAG40134.1 - 4e-84 282.2 1.1 7.5e-84 281.3 0.1 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 OAG40134.1 - 3.3e-68 229.1 0.3 7.7e-68 227.9 0.3 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 OAG40134.1 - 2.8e-34 118.3 0.0 5.8e-33 114.0 0.0 3.0 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.12 OAG40134.1 - 1.5e-24 86.9 4.1 1.7e-23 83.5 2.6 3.2 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.17 OAG40134.1 - 2.8e-18 65.8 0.2 1.6e-17 63.4 0.0 2.5 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 adh_short PF00106.25 OAG40136.1 - 6.1e-39 133.5 0.0 7.9e-39 133.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG40136.1 - 1.8e-32 112.7 0.0 2.4e-32 112.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG40136.1 - 1.3e-05 25.2 0.1 5.1e-05 23.3 0.1 1.9 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG40136.1 - 0.0095 15.4 0.0 0.17 11.3 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Sugar_tr PF00083.24 OAG40137.1 - 1.7e-86 290.9 19.8 1.9e-86 290.7 19.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG40137.1 - 3.5e-25 88.7 44.2 4.2e-19 68.7 20.5 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily GFO_IDH_MocA PF01408.22 OAG40139.1 - 6.8e-09 36.6 0.0 3.5e-08 34.3 0.0 2.0 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 OAG40139.1 - 0.067 13.2 0.1 0.17 11.9 0.1 1.7 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain Exotox-A_bind PF09101.10 OAG40139.1 - 0.15 11.4 0.5 5.8 6.2 0.0 2.2 2 0 0 2 2 2 0 Exotoxin A binding PrpF PF04303.13 OAG40140.1 - 1.6e-85 287.4 0.0 2e-85 287.0 0.0 1.0 1 0 0 1 1 1 1 PrpF protein DLH PF01738.18 OAG40141.1 - 1.4e-32 113.0 0.0 1.8e-32 112.7 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 OAG40141.1 - 3.6e-05 23.7 0.0 6e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OAG40141.1 - 0.0021 17.6 0.0 0.03 13.8 0.0 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family ADPrib_exo_Tox PF03496.14 OAG40141.1 - 0.11 11.8 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 ADP-ribosyltransferase exoenzyme Ammonium_transp PF00909.21 OAG40142.1 - 1.7e-75 254.2 30.9 2e-75 254.0 30.9 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family zf-PARP PF00645.18 OAG40143.1 - 5e-21 75.4 0.2 1.7e-20 73.6 0.2 2.0 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region DTHCT PF08070.11 OAG40143.1 - 1.8 9.3 66.8 0.8 10.5 16.0 5.4 2 1 2 4 4 4 0 DTHCT (NUC029) region APH PF01636.23 OAG40144.1 - 8e-15 55.4 0.1 1.6e-13 51.1 0.1 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 OAG40144.1 - 0.00013 21.6 0.0 0.00034 20.3 0.0 1.6 2 0 0 2 2 2 1 Choline/ethanolamine kinase DUF1679 PF07914.11 OAG40144.1 - 0.01 14.8 0.0 3.5 6.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) Peptidase_M7 PF02031.16 OAG40144.1 - 0.14 12.2 0.1 0.21 11.7 0.1 1.3 1 0 0 1 1 1 0 Streptomyces extracellular neutral proteinase (M7) family Lactamase_B_2 PF12706.7 OAG40145.1 - 5e-30 104.5 0.0 8.5e-29 100.5 0.0 2.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 OAG40145.1 - 3.7e-10 39.9 0.0 1.5e-09 37.9 0.0 2.0 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 OAG40145.1 - 0.00014 21.9 0.3 0.0014 18.6 0.1 2.4 3 0 0 3 3 3 1 Metallo-beta-lactamase superfamily BCS1_N PF08740.11 OAG40146.1 - 8.6e-46 156.3 1.6 1.2e-45 155.8 1.6 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 OAG40146.1 - 2.4e-18 66.8 0.0 4.7e-18 65.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OAG40146.1 - 4.9e-05 23.8 0.0 0.00014 22.3 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 OAG40146.1 - 0.00065 19.7 0.0 0.0017 18.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 OAG40146.1 - 0.0013 18.4 0.1 0.018 14.7 0.0 2.3 2 1 0 2 2 2 1 AAA domain DUF815 PF05673.13 OAG40146.1 - 0.0014 17.8 0.0 0.0023 17.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 OAG40146.1 - 0.0029 18.2 0.0 0.0062 17.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 OAG40146.1 - 0.0072 16.1 0.0 0.056 13.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 OAG40146.1 - 0.0097 15.4 0.0 0.018 14.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region PPV_E1_C PF00519.17 OAG40146.1 - 0.015 14.2 0.0 0.025 13.4 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase RNA_helicase PF00910.22 OAG40146.1 - 0.017 15.5 0.0 0.036 14.5 0.0 1.6 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.27 OAG40146.1 - 0.034 14.6 0.0 0.07 13.7 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_21 PF13304.6 OAG40146.1 - 0.034 13.9 0.0 0.062 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 OAG40146.1 - 0.038 13.7 0.0 0.089 12.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATPase PF06745.13 OAG40146.1 - 0.077 12.3 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_11 PF13086.6 OAG40146.1 - 0.079 12.7 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 OAG40146.1 - 0.11 12.7 0.0 0.33 11.1 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_28 PF13521.6 OAG40146.1 - 0.13 12.5 0.0 0.25 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 OAG40146.1 - 0.15 12.4 0.0 0.41 10.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain Ank_2 PF12796.7 OAG40147.1 - 1.6e-11 44.6 0.0 6.8e-10 39.4 0.0 2.9 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAG40147.1 - 2.6e-10 40.6 0.4 1.4e-07 31.9 0.0 4.0 2 2 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OAG40147.1 - 1e-08 35.3 0.2 5.1e-05 23.5 0.0 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 OAG40147.1 - 5.3e-08 33.0 0.3 0.00035 20.9 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat NACHT PF05729.12 OAG40147.1 - 1.8e-07 31.2 0.0 5.6e-07 29.6 0.0 1.9 1 0 0 1 1 1 1 NACHT domain Helo_like_N PF17111.5 OAG40147.1 - 5.6e-06 25.9 0.2 1.1e-05 24.9 0.2 1.5 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins AAA_16 PF13191.6 OAG40147.1 - 4.1e-05 24.0 0.1 0.00018 22.0 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain Ank_3 PF13606.6 OAG40147.1 - 0.0001 22.4 0.0 2.4 9.0 0.0 4.2 3 0 0 3 3 3 2 Ankyrin repeat AAA_22 PF13401.6 OAG40147.1 - 0.0034 17.6 0.0 0.016 15.5 0.0 2.2 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 OAG40147.1 - 0.025 15.0 0.0 0.057 13.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Methyltr_RsmB-F PF01189.17 OAG40148.1 - 1.3e-32 113.1 0.0 6.1e-26 91.3 0.0 2.9 2 1 0 2 2 2 2 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 OAG40148.1 - 0.0059 16.7 0.0 0.011 15.9 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Fungal_trans PF04082.18 OAG40150.1 - 3.2e-06 26.4 0.0 4.5e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 OAG40151.1 - 2.8e-21 75.8 46.2 2.8e-21 75.8 46.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Ste5_C PF12194.8 OAG40152.1 - 0.11 12.5 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein kinase Fus3-binding DUF5409 PF17421.2 OAG40153.1 - 0.1 13.3 0.1 0.18 12.6 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5409) NAD_binding_10 PF13460.6 OAG40154.1 - 1.9e-08 34.4 0.0 2.4e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 OAG40154.1 - 0.0029 16.7 0.0 0.004 16.2 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 OAG40154.1 - 0.065 12.4 0.0 0.16 11.2 0.0 1.7 1 1 1 2 2 2 0 Male sterility protein RNA_pol_Rpb5_C PF01191.19 OAG40155.1 - 3e-33 113.5 0.1 6.1e-33 112.5 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 OAG40155.1 - 1.3e-24 86.5 0.0 2.1e-24 85.9 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.12 OAG40155.1 - 0.0011 18.9 0.0 0.0025 17.8 0.0 1.6 1 0 0 1 1 1 1 Restriction endonuclease Sof1 PF04158.14 OAG40155.1 - 0.13 12.6 0.0 0.27 11.5 0.0 1.5 1 0 0 1 1 1 0 Sof1-like domain YabA PF06156.13 OAG40157.1 - 1.5 9.5 20.9 2.8 8.6 2.3 4.9 3 2 1 4 4 4 0 Initiation control protein YabA adh_short PF00106.25 OAG40158.1 - 6.1e-32 110.7 0.0 8.2e-32 110.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG40158.1 - 1.6e-25 90.0 0.0 2.1e-25 89.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG40158.1 - 2.8e-05 24.1 0.1 4e-05 23.6 0.1 1.2 1 0 0 1 1 1 1 KR domain NIP_1 PF08995.10 OAG40159.1 - 0.068 13.6 0.3 2 8.8 0.1 2.6 2 0 0 2 2 2 0 Necrosis inducing protein-1 PGM_PMM_I PF02878.16 OAG40160.1 - 7.6e-17 61.3 0.3 1.4e-07 31.3 0.0 3.1 3 0 0 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 OAG40160.1 - 1.4e-10 41.1 0.7 3.6e-10 39.9 0.7 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_II PF02879.16 OAG40160.1 - 0.0013 19.3 1.1 0.042 14.5 0.2 3.5 3 1 0 3 3 3 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 OAG40160.1 - 0.012 15.8 0.1 0.028 14.6 0.1 1.6 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III Per1 PF04080.13 OAG40161.1 - 2.8e-95 318.9 9.3 3.5e-95 318.6 9.3 1.0 1 0 0 1 1 1 1 Per1-like family DIL PF01843.19 OAG40162.1 - 6.5e-32 109.9 0.4 1.5e-31 108.7 0.4 1.7 1 0 0 1 1 1 1 DIL domain Ank_2 PF12796.7 OAG40162.1 - 3.3e-14 53.2 0.0 1e-13 51.6 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAG40162.1 - 2.4e-10 40.7 0.3 3.4e-07 30.7 0.2 3.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 OAG40162.1 - 2.5e-10 40.3 0.1 5e-05 23.6 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 OAG40162.1 - 1.2e-09 38.3 0.0 4.1e-06 27.0 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG40162.1 - 1.7e-07 31.0 1.3 0.00043 20.5 0.0 4.1 4 0 0 4 4 4 1 Ankyrin repeat MGC-24 PF05283.11 OAG40163.1 - 0.00046 20.6 4.0 0.00046 20.6 4.0 2.0 1 1 1 2 2 2 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin Podoplanin PF05808.11 OAG40163.1 - 0.0029 17.7 0.4 0.0029 17.7 0.4 1.5 2 0 0 2 2 2 1 Podoplanin DUF4690 PF15756.5 OAG40163.1 - 0.0044 17.6 2.3 0.0044 17.6 2.3 2.1 2 1 0 2 2 2 1 Small Novel Rich in Cartilage Amnionless PF14828.6 OAG40163.1 - 0.11 11.3 0.6 0.17 10.7 0.6 1.4 1 1 0 1 1 1 0 Amnionless LapA_dom PF06305.11 OAG40163.1 - 2.2 8.1 4.0 0.61 9.9 0.5 1.7 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain UCH PF00443.29 OAG40164.1 - 6.2e-23 81.6 0.0 7.9e-22 78.0 0.0 2.6 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase AAA PF00004.29 OAG40166.1 - 2.5e-51 173.6 0.0 5.2e-38 130.4 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OAG40166.1 - 3.1e-10 39.7 0.1 7.1e-10 38.5 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 OAG40166.1 - 2.8e-09 37.6 0.1 0.0011 19.3 0.0 2.9 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 OAG40166.1 - 3.6e-09 37.0 0.2 0.00014 22.2 0.0 3.4 2 2 1 3 3 3 2 AAA domain CDC48_2 PF02933.17 OAG40166.1 - 5.7e-09 35.6 0.3 9.7e-08 31.7 0.0 2.4 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_5 PF07728.14 OAG40166.1 - 7e-09 35.8 0.0 0.002 18.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 OAG40166.1 - 3.4e-08 33.8 0.0 0.0073 16.7 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_14 PF13173.6 OAG40166.1 - 4.1e-08 33.3 0.0 0.0011 19.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.12 OAG40166.1 - 1.7e-07 31.1 0.0 0.028 14.2 0.0 2.8 2 1 1 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 OAG40166.1 - 3.8e-07 30.7 0.0 0.016 15.8 0.0 3.1 3 0 0 3 3 3 2 AAA domain NACHT PF05729.12 OAG40166.1 - 4.9e-07 29.8 0.9 0.017 15.0 0.0 3.6 4 0 0 4 4 3 1 NACHT domain Mg_chelatase PF01078.21 OAG40166.1 - 6.7e-07 28.9 0.1 0.0054 16.1 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI NB-ARC PF00931.22 OAG40166.1 - 7.2e-07 28.7 0.0 0.045 12.9 0.0 3.3 3 0 0 3 3 3 2 NB-ARC domain AAA_33 PF13671.6 OAG40166.1 - 9e-07 29.1 0.0 0.035 14.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.14 OAG40166.1 - 1.7e-06 28.2 0.0 5.1e-05 23.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 OAG40166.1 - 4.8e-06 26.0 0.0 0.016 14.5 0.0 2.4 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_24 PF13479.6 OAG40166.1 - 6.4e-06 26.0 0.0 0.011 15.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 OAG40166.1 - 1.1e-05 25.7 0.0 0.19 12.0 0.0 2.3 2 0 0 2 2 2 2 AAA domain CDC48_N PF02359.18 OAG40166.1 - 2.2e-05 24.6 0.0 5.7e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain IstB_IS21 PF01695.17 OAG40166.1 - 2.6e-05 24.0 0.0 0.1 12.3 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein TsaE PF02367.17 OAG40166.1 - 0.0001 22.3 0.0 0.19 11.7 0.0 2.3 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 OAG40166.1 - 0.00011 22.8 0.3 0.045 14.3 0.1 2.8 3 0 0 3 3 2 1 ABC transporter AAA_7 PF12775.7 OAG40166.1 - 0.00018 21.1 0.2 0.026 14.0 0.0 2.7 3 0 0 3 3 2 1 P-loop containing dynein motor region ATPase PF06745.13 OAG40166.1 - 0.00029 20.3 0.5 0.036 13.4 0.1 2.7 2 1 1 3 3 3 1 KaiC PhoH PF02562.16 OAG40166.1 - 0.00037 20.0 0.0 0.52 9.7 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein AAA_25 PF13481.6 OAG40166.1 - 0.00068 19.3 0.2 2.1 7.9 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_17 PF13207.6 OAG40166.1 - 0.0007 20.0 0.3 0.42 11.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 OAG40166.1 - 0.00081 19.2 0.1 0.56 10.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 OAG40166.1 - 0.00099 19.1 0.3 7 6.5 0.0 3.3 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea Parvo_NS1 PF01057.17 OAG40166.1 - 0.0014 17.8 0.0 0.49 9.5 0.0 2.2 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.26 OAG40166.1 - 0.0029 17.3 0.0 0.66 9.7 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain TniB PF05621.11 OAG40166.1 - 0.0038 16.6 0.1 4.3 6.7 0.0 3.7 3 1 0 3 3 3 0 Bacterial TniB protein Rad17 PF03215.15 OAG40166.1 - 0.0043 17.0 0.0 4.3 7.2 0.0 2.7 3 0 0 3 3 2 0 Rad17 P-loop domain Vps4_C PF09336.10 OAG40166.1 - 0.0055 16.7 0.1 1.3 9.1 0.0 3.5 3 0 0 3 3 3 1 Vps4 C terminal oligomerisation domain AAA_30 PF13604.6 OAG40166.1 - 0.0058 16.4 0.0 0.41 10.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 OAG40166.1 - 0.0059 17.0 0.3 0.67 10.3 0.0 2.8 3 0 0 3 3 2 1 AAA domain Viral_helicase1 PF01443.18 OAG40166.1 - 0.012 15.4 0.0 0.11 12.2 0.0 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 OAG40166.1 - 0.016 15.2 0.0 4.2 7.4 0.1 2.6 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit DUF2075 PF09848.9 OAG40166.1 - 0.016 14.5 0.0 1.2 8.3 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_3 PF07726.11 OAG40166.1 - 0.017 15.0 0.0 0.54 10.1 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 OAG40166.1 - 0.028 14.3 0.1 13 5.7 0.0 2.8 3 0 0 3 3 2 0 NTPase Zeta_toxin PF06414.12 OAG40166.1 - 0.075 12.3 0.0 6.1 6.1 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin Glyoxalase PF00903.25 OAG40167.1 - 3.3e-11 43.5 0.0 6.3e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 OAG40167.1 - 0.0081 16.4 0.0 0.016 15.5 0.0 1.6 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyco_hydro_67M PF07488.12 OAG40168.1 - 1.7e-142 474.3 0.0 2.6e-142 473.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 middle domain Glyco_hydro_67C PF07477.12 OAG40168.1 - 3.1e-87 291.8 4.0 4.5e-87 291.3 4.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 C-terminus Glyco_hydro_67N PF03648.14 OAG40168.1 - 1.3e-25 90.0 0.0 2.4e-25 89.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 N-terminus Glyco_hydro_20b PF02838.15 OAG40168.1 - 0.0064 17.3 0.1 0.024 15.4 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 20, domain 2 Avidin PF01382.17 OAG40168.1 - 0.69 10.4 5.5 0.55 10.7 0.1 2.8 2 0 0 2 2 2 0 Avidin family F-box-like PF12937.7 OAG40169.1 - 0.18 11.7 0.1 0.18 11.7 0.1 2.0 2 0 0 2 2 2 0 F-box-like MFS_1 PF07690.16 OAG40170.1 - 7.5e-29 100.7 25.3 2.8e-28 98.9 25.8 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF3589 PF12141.8 OAG40171.1 - 9.4e-72 242.2 0.0 2.3e-69 234.3 0.0 2.2 1 1 0 1 1 1 1 Beta-mannosyltransferases CPSF100_C PF13299.6 OAG40171.1 - 2.2 8.4 8.9 1.8 8.7 6.6 1.8 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Sugar_tr PF00083.24 OAG40172.1 - 7.8e-80 268.9 14.9 9.9e-80 268.6 14.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG40172.1 - 5.7e-15 55.1 43.5 2.4e-13 49.7 21.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_C7 PF01830.18 OAG40172.1 - 0.064 12.7 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Peptidase C7 family MaoC_dehydratas PF01575.19 OAG40173.1 - 8.3e-22 77.0 0.0 1.7e-21 76.0 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 OAG40173.1 - 0.00093 19.3 0.0 0.0039 17.3 0.0 1.9 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase Methyltransf_25 PF13649.6 OAG40174.1 - 3.3e-12 46.9 0.0 7.5e-12 45.8 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG40174.1 - 2.8e-11 43.4 0.0 5.8e-11 42.4 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 OAG40174.1 - 3.2e-10 39.9 0.0 4.8e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 OAG40174.1 - 1.4e-08 34.7 0.0 1.5e-07 31.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG40174.1 - 3.6e-08 33.9 0.0 1.1e-07 32.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.11 OAG40174.1 - 1.7e-05 24.0 0.0 2.4e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_12 PF08242.12 OAG40174.1 - 3.3e-05 24.5 0.0 7e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OAG40174.1 - 0.00015 21.3 0.0 0.00026 20.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.19 OAG40174.1 - 0.00084 19.5 0.0 0.0018 18.4 0.0 1.6 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_18 PF12847.7 OAG40174.1 - 0.0011 18.9 0.0 0.0019 18.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 OAG40174.1 - 0.0015 17.9 0.0 0.002 17.5 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_16 PF10294.9 OAG40174.1 - 0.0022 17.7 0.1 0.0033 17.2 0.1 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_24 PF13578.6 OAG40174.1 - 0.0056 17.7 0.0 0.013 16.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 OAG40174.1 - 0.0082 16.1 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 OAG40174.1 - 0.017 14.9 0.1 0.028 14.2 0.1 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PRMT5_C PF17286.2 OAG40174.1 - 0.021 14.7 0.0 0.031 14.2 0.0 1.2 1 0 0 1 1 1 0 PRMT5 oligomerisation domain TehB PF03848.14 OAG40174.1 - 0.054 12.9 0.0 0.089 12.2 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB PRMT5 PF05185.16 OAG40174.1 - 0.073 12.9 0.1 0.14 12.0 0.1 1.4 1 1 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Cons_hypoth95 PF03602.15 OAG40174.1 - 0.19 11.3 0.0 0.28 10.8 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 MFS_1 PF07690.16 OAG40175.1 - 4.3e-29 101.6 25.4 4.3e-28 98.3 25.0 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF2681 PF10883.8 OAG40175.1 - 0.058 13.8 0.0 0.16 12.4 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) DUF485 PF04341.12 OAG40175.1 - 0.26 11.2 0.1 0.26 11.2 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function, DUF485 RasGEF PF00617.19 OAG40176.1 - 3.1e-44 151.3 0.2 5.4e-44 150.5 0.2 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 OAG40176.1 - 1.7e-12 47.5 0.3 4.5e-12 46.1 0.3 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif AA_permease PF00324.21 OAG40177.1 - 1.4e-147 492.1 37.0 1.6e-147 492.0 37.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAG40177.1 - 2.1e-35 122.4 40.4 2.5e-35 122.1 40.4 1.1 1 0 0 1 1 1 1 Amino acid permease DUF4781 PF16013.5 OAG40177.1 - 0.079 11.8 1.7 0.13 11.1 0.8 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4781) p450 PF00067.22 OAG40178.1 - 1.2e-84 284.7 0.0 1.7e-84 284.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.20 OAG40178.1 - 9.4e-31 107.1 0.0 1.5e-30 106.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 OAG40178.1 - 7.5e-27 94.3 0.0 1.4e-26 93.4 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 OAG40178.1 - 1.3e-11 45.1 0.0 2.8e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 OAG40178.1 - 0.0023 18.1 0.0 0.0047 17.2 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin domain Plant_NMP1 PF06694.11 OAG40178.1 - 0.06 12.4 0.0 0.81 8.7 0.0 2.1 2 0 0 2 2 2 0 Plant nuclear matrix protein 1 (NMP1) DUF1400 PF07176.11 OAG40178.1 - 0.089 13.1 0.3 0.23 11.7 0.3 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1400) Peptidase_M20 PF01546.28 OAG40179.1 - 1e-17 64.6 0.0 1.7e-17 63.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 OAG40179.1 - 1.9e-13 50.3 0.0 3.7e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain zf-C3HC4_2 PF13923.6 OAG40179.1 - 0.033 14.0 0.9 0.16 11.8 0.1 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OAG40179.1 - 0.034 14.4 0.0 0.094 13.0 0.0 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_2 PF13639.6 OAG40179.1 - 0.2 12.0 0.5 0.66 10.3 0.0 2.1 2 0 0 2 2 2 0 Ring finger domain MFS_1 PF07690.16 OAG40180.1 - 2.7e-39 135.1 35.2 2.7e-39 135.1 35.2 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Dynamin_N PF00350.23 OAG40182.1 - 1.4e-35 122.9 0.0 2.4e-35 122.0 0.0 1.4 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 OAG40182.1 - 2.6e-17 62.9 0.0 7.7e-17 61.4 0.0 1.8 1 1 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.23 OAG40182.1 - 1.2e-05 25.4 0.0 8.2e-05 22.7 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase GED PF02212.18 OAG40182.1 - 0.0043 17.2 0.1 0.097 12.8 0.0 2.9 2 1 0 2 2 2 1 Dynamin GTPase effector domain AAA_21 PF13304.6 OAG40182.1 - 0.011 15.6 0.0 0.019 14.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system FeoB_N PF02421.18 OAG40182.1 - 0.036 13.6 0.0 4.2 6.9 0.0 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_15 PF13175.6 OAG40182.1 - 0.046 13.4 0.0 0.075 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AviRa PF11599.8 OAG40182.1 - 0.067 12.6 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 RRNA methyltransferase AviRa AAA_29 PF13555.6 OAG40182.1 - 0.086 12.6 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Taeniidae_ag PF05596.11 OAG40182.1 - 0.15 12.0 0.0 0.59 10.1 0.0 2.0 1 0 0 1 1 1 0 Taeniidae antigen zf-primase PF09329.11 OAG40183.1 - 7.7e-18 64.0 0.5 1.5e-17 63.1 0.5 1.5 1 0 0 1 1 1 1 Primase zinc finger RNase_H2-Ydr279 PF09468.10 OAG40184.1 - 8.6e-34 117.0 1.2 3.4e-33 115.1 0.2 2.3 2 0 0 2 2 2 1 Ydr279p protein family (RNase H2 complex component) wHTH domain Ydr279_N PF17745.1 OAG40184.1 - 8.6e-20 70.8 1.5 3.2e-19 69.0 0.1 2.6 3 1 0 3 3 3 1 Ydr279p protein triple barrel domain ABC2_membrane PF01061.24 OAG40185.1 - 7.5e-82 273.8 53.0 3.3e-45 154.1 20.8 2.9 4 0 0 4 4 3 2 ABC-2 type transporter PDR_CDR PF06422.12 OAG40185.1 - 9.9e-37 124.7 2.9 2.5e-29 101.0 0.1 3.0 2 0 0 2 2 2 2 CDR ABC transporter ABC_tran PF00005.27 OAG40185.1 - 7.4e-35 120.4 0.0 5e-16 59.5 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_trans_N PF14510.6 OAG40185.1 - 4.6e-12 46.4 1.7 1.7e-11 44.6 1.7 2.1 1 1 0 1 1 1 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 OAG40185.1 - 9e-10 38.2 50.0 1.6e-08 34.1 12.5 3.3 3 0 0 3 3 3 2 ABC-2 family transporter protein RsgA_GTPase PF03193.16 OAG40185.1 - 9.9e-07 28.8 0.1 4.2e-06 26.8 0.1 1.9 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 OAG40185.1 - 1.8e-06 28.4 0.6 0.0015 18.9 0.0 2.9 3 0 0 3 3 2 1 AAA ATPase domain AAA_21 PF13304.6 OAG40185.1 - 9.1e-06 25.7 0.0 0.069 13.0 0.0 3.0 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 OAG40185.1 - 2.4e-05 24.0 0.1 0.0011 18.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 OAG40185.1 - 2.9e-05 23.7 0.0 0.023 14.4 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain T2SSE PF00437.20 OAG40185.1 - 0.00065 18.8 0.1 0.5 9.4 0.1 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_22 PF13401.6 OAG40185.1 - 0.00076 19.8 0.2 0.14 12.4 0.1 2.7 2 1 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 OAG40185.1 - 0.00086 19.4 0.1 0.23 11.6 0.1 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_28 PF13521.6 OAG40185.1 - 0.00093 19.5 0.3 0.0032 17.7 0.1 2.0 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 OAG40185.1 - 0.0013 19.3 0.0 0.011 16.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 OAG40185.1 - 0.0028 17.3 0.1 0.45 10.1 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 OAG40185.1 - 0.0038 17.2 0.0 0.12 12.3 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_30 PF13604.6 OAG40185.1 - 0.0095 15.7 0.1 0.099 12.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain dNK PF01712.19 OAG40185.1 - 0.016 15.0 0.0 0.074 12.9 0.0 2.1 2 0 0 2 2 1 0 Deoxynucleoside kinase AAA_33 PF13671.6 OAG40185.1 - 0.019 15.1 0.1 0.83 9.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 OAG40185.1 - 0.031 14.3 0.1 0.15 12.0 0.1 2.0 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SMC_N PF02463.19 OAG40185.1 - 0.034 13.6 0.0 6.4 6.1 0.0 2.9 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain IstB_IS21 PF01695.17 OAG40185.1 - 0.044 13.5 0.0 0.21 11.3 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein FtsK_SpoIIIE PF01580.18 OAG40185.1 - 0.052 12.9 0.0 11 5.3 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_17 PF13207.6 OAG40185.1 - 0.091 13.2 0.1 0.71 10.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 OAG40185.1 - 0.097 11.8 0.0 0.48 9.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA PF00004.29 OAG40185.1 - 0.097 13.1 0.1 2.8 8.4 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 OAG40185.1 - 0.15 12.0 0.2 6.6 6.7 0.1 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 OAG40185.1 - 0.18 11.5 0.0 2.5 7.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain Sporozoite_P67 PF05642.11 OAG40185.1 - 6.7 4.7 6.2 17 3.3 6.2 1.6 1 0 0 1 1 1 0 Sporozoite P67 surface antigen AAA_23 PF13476.6 OAG40185.1 - 6.8 7.1 11.0 0.06 13.8 0.5 2.8 4 1 0 4 4 2 0 AAA domain DUF5427 PF10310.9 OAG40186.1 - 0.18 10.7 3.9 0.24 10.3 3.9 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5427) 7TM_GPCR_Srd PF10317.9 OAG40186.1 - 0.19 10.9 1.0 0.26 10.4 1.0 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srd SOG2 PF10428.9 OAG40186.1 - 0.56 9.3 11.3 0.55 9.4 11.3 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Ribonuclease_3 PF00636.26 OAG40187.1 - 1e-16 61.4 0.1 4.7e-16 59.3 0.1 2.1 1 1 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 OAG40187.1 - 1.1e-15 58.0 0.0 2.2e-15 57.0 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.26 OAG40187.1 - 0.015 16.0 0.0 0.042 14.6 0.0 1.9 1 0 0 1 1 1 0 Double-stranded RNA binding motif MRP-S33 PF08293.11 OAG40188.1 - 6.9e-29 99.9 0.0 8.6e-29 99.6 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 adh_short_C2 PF13561.6 OAG40189.1 - 1.8e-63 214.3 1.3 2e-63 214.1 1.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG40189.1 - 3.7e-49 166.8 3.1 4.7e-49 166.5 3.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG40189.1 - 1.9e-06 27.9 0.5 2.9e-06 27.3 0.5 1.3 1 0 0 1 1 1 1 KR domain LppA PF16708.5 OAG40189.1 - 0.0053 16.7 0.4 1.3 9.0 0.0 2.8 3 1 0 3 3 3 2 Lipoprotein confined to pathogenic Mycobacterium TraT PF05818.12 OAG40189.1 - 0.065 12.9 2.3 0.099 12.3 2.3 1.2 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein Keratin_2_tail PF16210.5 OAG40190.1 - 0.0016 18.7 12.5 0.0016 18.7 12.5 2.2 2 0 0 2 2 2 1 Keratin type II cytoskeletal 1 tail DUF4515 PF14988.6 OAG40190.1 - 0.095 12.5 3.7 0.14 11.9 3.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4515) DUF1192 PF06698.11 OAG40190.1 - 0.13 12.4 5.2 0.33 11.1 5.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) Med21 PF11221.8 OAG40190.1 - 0.19 12.0 2.4 0.53 10.5 2.4 1.7 1 0 0 1 1 1 0 Subunit 21 of Mediator complex DUF382 PF04037.13 OAG40191.1 - 2.2e-59 199.1 0.8 2.2e-59 199.1 0.8 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF382) PSP PF04046.16 OAG40191.1 - 1.3e-21 76.1 4.8 3.1e-21 75.0 4.8 1.7 1 0 0 1 1 1 1 PSP Med8 PF10232.9 OAG40191.1 - 0.11 12.1 2.9 0.34 10.5 2.9 1.8 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 GFA PF04828.14 OAG40192.1 - 9.1e-09 35.5 2.6 1e-06 29.0 0.2 2.8 2 1 0 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme TFIIB PF00382.19 OAG40193.1 - 5.1e-27 93.7 0.1 3.9e-13 49.2 0.0 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 OAG40193.1 - 3.7e-09 35.9 0.5 6.8e-09 35.1 0.5 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.23 OAG40193.1 - 4.3e-06 26.5 0.2 8.8e-06 25.5 0.2 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 OAG40193.1 - 0.00042 20.4 0.0 1.5 9.0 0.0 2.4 2 0 0 2 2 2 2 Cyclin, C-terminal domain Sigma70_r4_2 PF08281.12 OAG40193.1 - 0.034 13.8 0.0 0.092 12.4 0.0 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 GerE PF00196.19 OAG40193.1 - 0.049 13.2 0.1 0.16 11.5 0.0 1.9 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family zf-ribbon_3 PF13248.6 OAG40193.1 - 0.15 11.5 4.7 1.5 8.3 4.7 2.2 1 1 0 1 1 1 0 zinc-ribbon domain ATP_sub_h PF10775.9 OAG40194.1 - 1.3e-23 82.8 3.8 2e-23 82.1 3.8 1.3 1 0 0 1 1 1 1 ATP synthase complex subunit h DUF740 PF05340.12 OAG40194.1 - 0.08 11.7 0.3 0.082 11.7 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF740) DUF1765 PF08578.10 OAG40195.1 - 6.6e-41 139.7 8.4 9.9e-41 139.1 7.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1765) DUF685 PF05085.12 OAG40195.1 - 0.23 10.7 0.0 0.52 9.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF685) AMP-binding PF00501.28 OAG40196.1 - 3.5e-94 315.8 0.0 4.5e-94 315.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG40196.1 - 4.4e-14 53.2 0.1 9.3e-14 52.2 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Arginase PF00491.21 OAG40197.1 - 2.3e-75 253.7 1.6 2.8e-75 253.4 1.6 1.0 1 0 0 1 1 1 1 Arginase family p450 PF00067.22 OAG40198.1 - 4.2e-69 233.5 0.0 5e-69 233.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ecm29 PF13001.7 OAG40198.1 - 0.12 11.0 0.0 0.17 10.6 0.0 1.1 1 0 0 1 1 1 0 Proteasome stabiliser PMT_4TMC PF16192.5 OAG40198.1 - 0.75 9.3 3.9 1.3 8.5 3.9 1.3 1 0 0 1 1 1 0 C-terminal four TMM region of protein-O-mannosyltransferase GatB_N PF02934.15 OAG40199.1 - 1.3e-93 313.4 0.0 1.7e-93 313.0 0.0 1.2 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 OAG40199.1 - 2e-21 76.4 0.0 3.4e-21 75.7 0.0 1.3 1 0 0 1 1 1 1 GatB domain Abhydrolase_1 PF00561.20 OAG40200.1 - 1.5e-14 54.3 0.0 8.4e-14 51.8 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG40200.1 - 6.3e-13 49.8 0.1 1.3e-12 48.8 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG40200.1 - 1.1e-11 44.5 0.0 2.6e-08 33.4 0.0 2.6 2 0 0 2 2 2 2 Serine aminopeptidase, S33 DSPc PF00782.20 OAG40200.1 - 4.1e-09 36.3 0.0 8e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Ser_hydrolase PF06821.13 OAG40200.1 - 6.5e-05 22.9 0.0 0.003 17.4 0.0 2.5 2 0 0 2 2 2 1 Serine hydrolase Y_phosphatase PF00102.27 OAG40200.1 - 0.0023 17.5 0.0 0.0041 16.7 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PGAP1 PF07819.13 OAG40200.1 - 0.0087 15.8 0.0 0.12 12.1 0.0 2.1 2 0 0 2 2 2 1 PGAP1-like protein PTPlike_phytase PF14566.6 OAG40200.1 - 0.023 14.8 0.0 0.047 13.8 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate DUF900 PF05990.12 OAG40200.1 - 0.052 13.0 0.0 0.12 11.9 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Y_phosphatase3 PF13350.6 OAG40200.1 - 0.13 12.2 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family Lipase_3 PF01764.25 OAG40200.1 - 0.16 11.8 0.0 0.33 10.8 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) IBN_N PF03810.19 OAG40201.1 - 8.2e-15 54.5 0.4 6.8e-14 51.5 0.1 2.9 3 0 0 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.12 OAG40201.1 - 0.0029 17.7 3.6 0.014 15.5 0.8 3.4 3 0 0 3 3 3 1 Exportin 1-like protein GAIN PF16489.5 OAG40201.1 - 4.7 6.6 6.3 1.3 8.4 0.9 2.7 2 1 1 3 3 3 0 GPCR-Autoproteolysis INducing (GAIN) domain Pex2_Pex12 PF04757.14 OAG40202.1 - 1.2e-35 123.1 4.5 1.8e-35 122.6 4.5 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.6 OAG40202.1 - 0.00095 19.3 4.6 0.00095 19.3 4.6 2.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 OAG40202.1 - 0.0069 16.4 2.9 0.026 14.5 2.9 1.9 1 1 0 1 1 1 1 RING-type zinc-finger NST1 PF13945.6 OAG40202.1 - 0.11 12.6 0.1 0.22 11.6 0.1 1.5 1 0 0 1 1 1 0 Salt tolerance down-regulator zf-C3HC4 PF00097.25 OAG40202.1 - 0.11 12.4 2.2 0.32 10.9 2.2 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Lactamase_B PF00753.27 OAG40203.1 - 7.1e-19 68.6 1.6 9.8e-19 68.1 1.6 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OAG40203.1 - 7.1e-05 22.4 0.1 0.00016 21.3 0.1 1.6 2 0 0 2 2 2 1 Beta-lactamase superfamily domain NYN PF01936.18 OAG40204.1 - 1.7e-05 25.3 0.0 0.00011 22.7 0.0 2.2 2 1 0 2 2 2 1 NYN domain MFS_1 PF07690.16 OAG40205.1 - 1.3e-20 73.6 55.0 3.1e-14 52.7 26.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG40205.1 - 5.3e-05 22.3 31.0 0.0015 17.4 2.2 3.0 2 2 0 3 3 3 2 Sugar (and other) transporter SH PF01445.17 OAG40205.1 - 0.33 10.9 1.8 0.86 9.6 1.8 1.6 1 0 0 1 1 1 0 Viral small hydrophobic protein YrhC PF14143.6 OAG40205.1 - 3.1 8.0 10.9 12 6.1 0.4 3.6 3 0 0 3 3 3 0 YrhC-like protein TUTF7_u4 PF16631.5 OAG40206.1 - 0.0036 17.9 4.9 0.0079 16.8 4.9 1.5 1 0 0 1 1 1 1 Unstructured region 4 on terminal uridylyltransferase 7 Dynamin_N PF00350.23 OAG40208.1 - 3.5e-13 50.0 0.0 1.3e-12 48.1 0.0 2.1 1 1 1 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 OAG40208.1 - 0.00064 19.8 0.0 0.0078 16.3 0.0 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 OAG40208.1 - 0.0013 19.3 0.1 0.0055 17.2 0.0 2.1 2 0 0 2 2 2 1 ABC transporter AAA_16 PF13191.6 OAG40208.1 - 0.002 18.6 0.1 0.002 18.6 0.1 2.6 3 0 0 3 3 3 1 AAA ATPase domain RsgA_GTPase PF03193.16 OAG40208.1 - 0.021 14.7 0.0 0.099 12.5 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase DUF1869 PF08956.10 OAG40208.1 - 0.028 14.3 0.6 14 5.7 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF1869) Viral_helicase1 PF01443.18 OAG40208.1 - 0.049 13.4 0.0 0.19 11.5 0.0 2.0 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase DUF4407 PF14362.6 OAG40208.1 - 1.3 8.4 5.5 0.45 9.8 1.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) THOC7 PF05615.13 OAG40208.1 - 2.6 8.3 8.3 0.26 11.6 0.8 3.2 4 0 0 4 4 4 0 Tho complex subunit 7 Ribosomal_L11_N PF03946.14 OAG40209.1 - 1.2e-23 82.7 0.2 1.9e-23 82.0 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 OAG40209.1 - 3.8e-13 49.7 0.0 7.1e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Sec23_trunk PF04811.15 OAG40210.1 - 4e-75 252.5 0.0 5.5e-75 252.1 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 OAG40210.1 - 5e-30 104.1 0.1 1e-29 103.1 0.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 OAG40210.1 - 7.2e-24 83.6 0.0 1.6e-23 82.4 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 OAG40210.1 - 2.8e-15 56.1 2.8 4.9e-15 55.3 2.8 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 OAG40210.1 - 6.8e-11 41.9 0.0 1.7e-10 40.6 0.0 1.8 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 OAG40210.1 - 0.085 12.3 0.4 0.21 11.0 0.1 1.8 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain UL42 PF17638.2 OAG40210.1 - 0.32 11.0 4.9 0.07 13.1 0.7 1.9 2 0 0 2 2 2 0 HCMV UL42 Coatomer_WDAD PF04053.14 OAG40211.1 - 1.9e-144 482.1 0.0 3.2e-144 481.3 0.0 1.4 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.11 OAG40211.1 - 3.6e-103 345.4 0.0 5.5e-103 344.8 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.32 OAG40211.1 - 3.8e-35 119.3 15.9 2.4e-07 31.3 0.2 7.4 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG40211.1 - 1e-07 32.1 0.8 0.0054 17.0 0.0 5.0 3 2 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OAG40211.1 - 0.025 13.2 7.6 2.4 6.7 0.1 3.9 2 1 2 4 4 4 0 Nucleoporin Nup120/160 IPPT PF01715.17 OAG40211.1 - 0.08 12.7 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 IPP transferase Beta-lactamase PF00144.24 OAG40212.1 - 7.5e-44 150.3 3.3 2.9e-43 148.4 3.3 1.8 1 1 0 1 1 1 1 Beta-lactamase SET PF00856.28 OAG40213.1 - 8.1e-15 55.6 0.1 1.9e-14 54.4 0.1 1.7 1 1 0 1 1 1 1 SET domain ATP-synt PF00231.19 OAG40213.1 - 0.032 13.9 0.0 0.056 13.2 0.0 1.5 1 0 0 1 1 1 0 ATP synthase RasGAP PF00616.19 OAG40214.1 - 2.2e-56 190.9 0.1 4.6e-56 189.8 0.1 1.6 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 OAG40214.1 - 6.3e-32 110.6 0.3 6.3e-32 110.6 0.3 2.9 4 0 0 4 4 4 1 RasGAP C-terminus NYD-SP28_assoc PF14775.6 OAG40214.1 - 0.83 9.8 3.9 7.6 6.7 0.0 3.5 3 0 0 3 3 3 0 Sperm tail C-terminal domain DUF724 PF05266.14 OAG40214.1 - 2.4 7.9 5.9 5.9 6.7 1.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Glyco_hydro_18 PF00704.28 OAG40215.1 - 6.1e-88 295.5 0.5 7e-88 295.3 0.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 ApbA PF02558.16 OAG40216.1 - 1.2e-30 106.2 0.0 1.9e-30 105.5 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 OAG40216.1 - 5.3e-26 91.3 0.0 1.5e-24 86.6 0.0 2.1 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA C terminal Sacchrp_dh_NADP PF03435.18 OAG40216.1 - 0.086 13.1 0.0 0.25 11.6 0.0 1.8 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain GFA PF04828.14 OAG40217.1 - 2.9e-08 33.9 0.0 4.2e-08 33.4 0.0 1.3 1 1 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Gaa1 PF04114.14 OAG40218.1 - 1.9e-159 531.9 3.0 2.7e-159 531.4 3.0 1.2 1 0 0 1 1 1 1 Gaa1-like, GPI transamidase component Rhomboid PF01694.22 OAG40218.1 - 1.2e-16 61.0 5.2 1.2e-16 61.0 5.2 2.4 2 0 0 2 2 2 1 Rhomboid family Ytp1 PF10355.9 OAG40219.1 - 1.3e-119 398.5 10.3 2e-119 397.9 10.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 OAG40219.1 - 1.3e-25 89.2 9.0 1.3e-25 89.2 9.0 3.4 5 0 0 5 5 5 2 Domain of unknown function (DUF2427) DUF3382 PF11862.8 OAG40219.1 - 0.87 9.9 6.7 15 5.9 0.1 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF3382) UCH PF00443.29 OAG40220.1 - 7.7e-48 163.2 0.2 1.1e-47 162.8 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OAG40220.1 - 3.8e-18 66.2 5.6 1.4e-16 61.0 5.6 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 OAG40220.1 - 0.0023 18.3 0.6 0.0023 18.3 0.6 3.2 4 0 0 4 4 4 1 Zn-finger in ubiquitin-hydrolases and other protein Rpn3_C PF08375.11 OAG40221.1 - 2.1e-25 88.9 1.6 2.1e-25 88.9 1.6 2.2 2 0 0 2 2 2 1 Proteasome regulatory subunit C-terminal PCI PF01399.27 OAG40221.1 - 5.6e-21 75.0 0.3 2.4e-20 73.0 0.1 2.2 2 0 0 2 2 2 1 PCI domain CSN8_PSD8_EIF3K PF10075.9 OAG40221.1 - 0.021 14.8 0.1 0.052 13.5 0.1 1.7 1 1 0 1 1 1 0 CSN8/PSMD8/EIF3K family DASH_Spc34 PF08657.10 OAG40222.1 - 9.4e-39 133.7 5.8 5.2e-24 85.4 0.4 2.1 1 1 1 2 2 2 2 DASH complex subunit Spc34 GARP PF16731.5 OAG40222.1 - 0.021 14.5 0.2 0.032 13.9 0.2 1.3 1 0 0 1 1 1 0 Glutamic acid/alanine-rich protein of Trypanosoma DUF1604 PF07713.13 OAG40223.1 - 0.89 9.4 5.3 13 5.7 0.1 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1604) EMP24_GP25L PF01105.24 OAG40224.1 - 4.5e-43 147.3 0.0 5.7e-43 147.0 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD EzrA PF06160.12 OAG40224.1 - 0.011 14.0 0.9 0.014 13.6 0.9 1.0 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA YabA PF06156.13 OAG40224.1 - 0.18 12.5 0.5 0.43 11.2 0.6 1.5 2 0 0 2 2 2 0 Initiation control protein YabA BTB PF00651.31 OAG40225.1 - 1.8e-10 41.0 0.0 3.5e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 OAG40226.1 - 1.1e-06 28.8 0.0 1.8e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain APH PF01636.23 OAG40227.1 - 5.2e-38 131.3 0.0 7.9e-38 130.7 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 OAG40227.1 - 0.0014 18.0 0.0 0.0021 17.5 0.0 1.3 1 1 0 1 1 1 1 Ecdysteroid kinase Fructosamin_kin PF03881.14 OAG40227.1 - 0.0015 17.8 0.0 0.0079 15.4 0.0 1.9 1 1 0 1 1 1 1 Fructosamine kinase Choline_kinase PF01633.20 OAG40227.1 - 0.13 11.8 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Sugar_tr PF00083.24 OAG40228.1 - 6.1e-74 249.5 18.6 7.1e-74 249.3 18.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG40228.1 - 1.9e-18 66.6 25.4 1.9e-18 66.6 25.4 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF3493 PF11998.8 OAG40228.1 - 1.6 8.9 4.3 1.5 9.1 0.3 2.9 2 1 1 3 3 3 0 Low psii accumulation1 / Rep27 EMP70 PF02990.16 OAG40228.1 - 3.9 6.0 12.0 4.1 6.0 0.1 2.7 2 1 1 3 3 3 0 Endomembrane protein 70 Cyclase PF04199.13 OAG40229.1 - 4.7e-16 59.3 0.3 9e-16 58.3 0.3 1.4 1 1 0 1 1 1 1 Putative cyclase adh_short_C2 PF13561.6 OAG40230.1 - 1.1e-52 179.0 0.2 1.3e-52 178.7 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG40230.1 - 2.7e-41 141.2 0.1 3.5e-41 140.8 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG40230.1 - 1.3e-05 25.2 0.4 5.9e-05 23.0 0.4 1.8 1 1 0 1 1 1 1 KR domain CLU PF13236.6 OAG40230.1 - 0.11 12.3 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Clustered mitochondria AMP-binding PF00501.28 OAG40231.1 - 2.6e-81 273.4 0.0 3.3e-81 273.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG40231.1 - 1.1e-14 55.1 0.9 2.7e-14 53.9 0.2 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Acyl-CoA_dh_1 PF00441.24 OAG40232.1 - 3e-22 79.5 1.7 4.5e-22 78.9 1.7 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 OAG40232.1 - 6.4e-14 52.6 0.0 1.2e-13 51.7 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 OAG40232.1 - 1.3e-10 41.4 0.0 2.4e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 OAG40232.1 - 6.1e-07 29.8 0.1 1e-06 29.1 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DUF3425 PF11905.8 OAG40233.1 - 2.1e-12 47.1 0.8 4.2e-12 46.1 0.8 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) CCDC24 PF15669.5 OAG40233.1 - 0.0046 16.9 2.3 0.0076 16.2 2.3 1.3 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 24 family DUF5347 PF17282.2 OAG40233.1 - 0.091 13.1 0.4 0.18 12.2 0.4 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5347) Eaf7 PF07904.13 OAG40233.1 - 0.14 12.5 0.0 0.33 11.3 0.0 1.6 1 0 0 1 1 1 0 Chromatin modification-related protein EAF7 bZIP_1 PF00170.21 OAG40233.1 - 0.64 10.1 10.6 1.1 9.4 10.6 1.4 1 0 0 1 1 1 0 bZIP transcription factor BTB PF00651.31 OAG40234.1 - 3.1e-08 33.8 0.0 5.4e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 OAG40235.1 - 4.1e-08 33.4 0.0 6.4e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 OAG40236.1 - 1e-08 35.4 0.0 1.3e-08 35.1 0.0 1.1 1 0 0 1 1 1 1 BTB/POZ domain AIM24 PF01987.17 OAG40237.1 - 6.5e-49 166.5 0.0 8.2e-49 166.1 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 MFS_1 PF07690.16 OAG40239.1 - 2.4e-32 112.2 36.0 1.3e-23 83.6 19.0 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG40239.1 - 4.5e-10 39.0 3.3 4.5e-10 39.0 3.3 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_3 PF05977.13 OAG40239.1 - 0.0078 14.7 6.5 0.18 10.2 2.8 2.3 2 0 0 2 2 2 2 Transmembrane secretion effector ABC_membrane PF00664.23 OAG40240.1 - 4.3e-39 134.8 14.1 5.6e-39 134.4 14.1 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 OAG40240.1 - 1.1e-33 116.7 0.0 2.3e-33 115.6 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 OAG40240.1 - 1.1e-05 25.0 0.1 0.013 14.9 0.0 2.7 2 1 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 OAG40240.1 - 0.00014 22.2 0.1 0.0014 18.9 0.0 2.5 2 1 0 2 2 1 1 AAA domain AAA_16 PF13191.6 OAG40240.1 - 0.00015 22.2 0.0 0.00042 20.7 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 OAG40240.1 - 0.00096 19.2 0.0 0.013 15.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 OAG40240.1 - 0.0016 18.3 0.0 0.013 15.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_24 PF13479.6 OAG40240.1 - 0.0039 16.9 0.0 0.0077 16.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 OAG40240.1 - 0.016 14.9 0.1 0.041 13.6 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_15 PF13175.6 OAG40240.1 - 0.019 14.7 0.2 0.053 13.2 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain Rad17 PF03215.15 OAG40240.1 - 0.022 14.7 0.0 0.048 13.6 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_23 PF13476.6 OAG40240.1 - 0.022 15.3 0.0 0.078 13.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 OAG40240.1 - 0.024 14.6 0.0 0.073 13.0 0.0 1.8 2 0 0 2 2 1 0 RsgA GTPase IstB_IS21 PF01695.17 OAG40240.1 - 0.025 14.3 1.7 8 6.1 0.2 3.1 2 1 1 3 3 3 0 IstB-like ATP binding protein SbcCD_C PF13558.6 OAG40240.1 - 0.038 14.2 0.5 3 8.1 0.1 3.2 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit MMR_HSR1 PF01926.23 OAG40240.1 - 0.041 14.0 0.0 0.1 12.6 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_18 PF13238.6 OAG40240.1 - 0.044 14.3 0.0 0.14 12.7 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 OAG40240.1 - 0.045 13.3 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA PF00004.29 OAG40240.1 - 0.046 14.2 0.0 0.24 11.8 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 OAG40240.1 - 0.071 13.4 0.0 0.25 11.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.25 OAG40240.1 - 0.091 12.4 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_25 PF13481.6 OAG40240.1 - 0.094 12.3 0.0 0.29 10.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 OAG40240.1 - 0.094 12.7 0.0 0.25 11.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Vac14_Fig4_bd PF11916.8 OAG40241.1 - 3.4e-80 267.9 5.1 3.4e-80 267.9 5.1 1.7 2 0 0 2 2 2 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 OAG40241.1 - 8.7e-33 112.8 0.2 1.5e-28 99.3 0.3 4.8 4 1 0 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT PF02985.22 OAG40241.1 - 1.9e-07 30.8 1.2 0.00073 19.6 0.0 4.7 4 0 0 4 4 4 1 HEAT repeat Cnd1 PF12717.7 OAG40241.1 - 5.2e-05 23.3 0.8 0.029 14.4 0.3 3.4 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 OAG40241.1 - 8.5e-05 23.0 3.2 0.0011 19.4 0.1 4.1 4 0 0 4 4 4 1 HEAT-like repeat Arm PF00514.23 OAG40241.1 - 0.0049 16.9 0.0 0.72 10.0 0.0 3.6 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 OAG40241.1 - 0.044 14.2 7.5 1.4 9.3 0.2 4.8 6 1 1 7 7 7 0 HEAT repeats SNF2_N PF00176.23 OAG40242.1 - 4.2e-59 200.0 0.0 6.2e-59 199.5 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.10 OAG40242.1 - 2.8e-47 161.2 0.4 1.1e-46 159.2 0.3 2.0 2 0 0 2 2 2 1 Rad54 N terminal Helicase_C PF00271.31 OAG40242.1 - 3.1e-16 59.7 0.0 7.6e-16 58.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG40242.1 - 6.3e-07 29.6 0.0 1.3e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 OAG40242.1 - 0.00019 20.7 0.0 0.00099 18.4 0.0 2.1 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 SWI2_SNF2 PF18766.1 OAG40242.1 - 0.089 12.4 0.0 0.24 11.0 0.0 1.7 1 1 0 1 1 1 0 SWI2/SNF2 ATPase Mito_carr PF00153.27 OAG40243.1 - 4.9e-37 125.7 7.9 2.5e-15 56.2 0.2 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein Rab5ip PF07019.12 OAG40243.1 - 1.4 9.5 5.4 2.8 8.6 0.7 3.3 2 2 0 2 2 2 0 Rab5-interacting protein (Rab5ip) zf-C2H2_jaz PF12171.8 OAG40244.1 - 2.8e-09 37.0 3.7 5e-09 36.2 3.7 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 OAG40244.1 - 0.012 16.1 1.9 0.012 16.1 1.9 2.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 OAG40244.1 - 0.019 15.3 2.6 0.032 14.6 1.2 1.8 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-U1 PF06220.12 OAG40244.1 - 0.035 13.9 1.4 0.063 13.1 1.4 1.4 1 0 0 1 1 1 0 U1 zinc finger zf-H2C2_2 PF13465.6 OAG40244.1 - 0.053 14.0 2.3 0.14 12.6 0.0 2.4 2 0 0 2 2 2 0 Zinc-finger double domain zf-met PF12874.7 OAG40244.1 - 0.061 13.7 2.5 0.14 12.6 2.5 1.6 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 OAG40244.1 - 0.25 12.3 1.2 0.25 12.3 1.2 2.0 2 1 0 2 2 2 0 C2H2-type zinc finger Aconitase PF00330.20 OAG40245.1 - 9.7e-150 499.6 0.0 1.2e-149 499.3 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 OAG40245.1 - 2.3e-44 150.9 0.0 3.8e-44 150.2 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain BLACT_WH PF17778.1 OAG40246.1 - 3.6e-16 58.9 0.2 6.3e-16 58.1 0.2 1.4 1 0 0 1 1 1 1 Beta-lactamase associated winged helix domain Lactamase_B PF00753.27 OAG40246.1 - 4.3e-09 36.7 3.0 7.7e-09 35.8 2.3 2.0 1 1 1 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OAG40246.1 - 4.7e-08 32.8 0.5 5.9e-08 32.5 0.5 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_6 PF16661.5 OAG40246.1 - 0.022 14.2 0.0 0.036 13.5 0.0 1.3 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily domain HEM4 PF02602.15 OAG40247.1 - 1.5e-31 109.6 0.1 2.2e-11 43.5 0.0 3.8 3 1 0 3 3 3 3 Uroporphyrinogen-III synthase HemD MCU PF04678.13 OAG40249.1 - 1.3e-27 97.1 0.0 2.4e-27 96.1 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial calcium uniporter Ribosomal_S15 PF00312.22 OAG40249.1 - 0.058 13.6 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein S15 dsrm PF00035.26 OAG40250.1 - 0.0032 18.1 0.0 0.0067 17.1 0.0 1.4 1 0 0 1 1 1 1 Double-stranded RNA binding motif DND1_DSRM PF14709.7 OAG40250.1 - 0.11 12.8 0.9 0.3 11.4 0.9 1.7 1 1 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 Prenyltrans PF00432.21 OAG40251.1 - 4.8e-29 99.8 30.1 1.5e-11 43.8 2.7 5.2 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 OAG40251.1 - 0.16 11.0 0.1 0.32 10.0 0.0 1.5 2 0 0 2 2 2 0 Squalene-hopene cyclase C-terminal domain Zn_clus PF00172.18 OAG40252.1 - 0.0031 17.6 7.7 0.0069 16.5 7.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_transf_20 PF00982.21 OAG40253.1 - 2.3e-201 669.6 0.0 2.7e-201 669.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glyco_trans_1_4 PF13692.6 OAG40253.1 - 0.0028 18.1 0.0 0.006 17.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 OAG40253.1 - 0.027 14.2 0.2 0.14 11.9 0.1 2.1 2 0 0 2 2 2 0 Starch synthase catalytic domain Ribosomal_S17 PF00366.20 OAG40254.1 - 5.7e-13 48.8 0.0 1.3e-12 47.6 0.0 1.7 1 0 0 1 1 1 1 Ribosomal protein S17 PCI PF01399.27 OAG40255.1 - 2e-08 34.7 0.0 5.9e-08 33.2 0.0 1.9 1 0 0 1 1 1 1 PCI domain Rpn9_C PF18261.1 OAG40255.1 - 4.8e-07 29.3 0.6 1.2e-06 27.9 0.6 1.7 1 0 0 1 1 1 1 Rpn9 C-terminal helix TPR_8 PF13181.6 OAG40255.1 - 0.017 15.3 0.2 0.061 13.6 0.2 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 OAG40255.1 - 0.066 14.1 0.2 0.32 11.9 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 OAG40255.1 - 0.07 13.3 0.2 0.34 11.1 0.2 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat Dimerisation2 PF16864.5 OAG40255.1 - 0.072 13.1 0.0 10 6.2 0.0 2.5 2 0 0 2 2 2 0 Dimerisation domain Fungal_trans_2 PF11951.8 OAG40256.1 - 8.5e-10 38.0 0.5 1.2e-09 37.5 0.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Vps51 PF08700.11 OAG40257.1 - 2.3e-24 85.3 0.6 5.5e-24 84.1 0.6 1.7 1 0 0 1 1 1 1 Vps51/Vps67 COG5 PF10392.9 OAG40257.1 - 0.007 16.5 0.1 0.017 15.3 0.1 1.6 1 0 0 1 1 1 1 Golgi transport complex subunit 5 Sec5 PF15469.6 OAG40257.1 - 0.033 14.0 0.0 0.093 12.5 0.0 1.7 2 0 0 2 2 2 0 Exocyst complex component Sec5 DUF2115 PF09888.9 OAG40257.1 - 0.11 13.0 0.4 2.6 8.5 0.2 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2115) MGC-24 PF05283.11 OAG40257.1 - 6.9 7.1 6.2 8.3 6.9 4.9 1.8 1 1 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin VID27 PF08553.10 OAG40258.1 - 1.8e-186 619.3 0.0 2.5e-186 618.9 0.0 1.2 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain VID27_N PF17748.1 OAG40258.1 - 3.7e-75 251.5 0.7 3.7e-75 251.5 0.7 3.2 2 1 1 3 3 3 1 VID27 N-terminal region VID27_PH PF17747.1 OAG40258.1 - 4.5e-44 149.2 0.3 1.4e-43 147.6 0.1 2.0 2 0 0 2 2 2 1 VID27 PH-like domain TLD PF07534.16 OAG40259.1 - 2.8e-25 89.2 0.0 4.7e-15 56.0 0.0 2.2 2 0 0 2 2 2 2 TLD Zn_clus PF00172.18 OAG40260.1 - 9e-09 35.3 13.4 1.5e-08 34.6 13.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldose_epim PF01263.20 OAG40261.1 - 1.2e-64 218.6 0.1 1.5e-64 218.2 0.1 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase ANAPC1 PF12859.7 OAG40262.1 - 4.2e-19 69.4 1.6 9.1e-19 68.3 0.1 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.22 OAG40262.1 - 8.6e-08 32.3 0.2 0.00071 19.9 0.0 4.3 4 0 0 4 4 4 1 Proteasome/cyclosome repeat eIF2A PF08662.11 OAG40264.1 - 4.6e-82 274.6 0.0 5.7e-80 267.8 0.0 2.3 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 OAG40264.1 - 0.035 15.0 3.3 9.5 7.3 0.1 5.1 5 1 0 6 6 6 0 WD domain, G-beta repeat DUF3405 PF11885.8 OAG40267.1 - 3.5e-169 563.7 5.9 4.1e-169 563.5 5.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) Ring_hydroxyl_A PF00848.19 OAG40268.1 - 7e-17 62.1 0.2 1.1e-13 51.7 0.2 2.3 1 1 0 1 1 1 1 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.26 OAG40268.1 - 1.7e-15 56.7 0.0 3.3e-15 55.8 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain IBR PF01485.21 OAG40269.1 - 1.9e-06 28.0 6.3 1.9e-06 28.0 6.3 3.1 3 0 0 3 3 3 1 IBR domain, a half RING-finger domain zf-RING_UBOX PF13445.6 OAG40269.1 - 0.0065 16.5 6.6 0.0065 16.5 6.6 2.2 3 0 0 3 3 3 1 RING-type zinc-finger zf-RING_2 PF13639.6 OAG40269.1 - 0.0086 16.4 7.9 0.0086 16.4 7.9 3.0 2 1 1 3 3 3 1 Ring finger domain zinc_ribbon_5 PF13719.6 OAG40269.1 - 0.76 9.6 3.5 4.9 7.0 0.1 2.8 3 0 0 3 3 3 0 zinc-ribbon domain zf-C3HC4 PF00097.25 OAG40269.1 - 7.2 6.6 22.0 0.018 14.9 10.5 2.5 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Ribosomal_S19e PF01090.19 OAG40270.1 - 3.6e-43 146.6 0.1 4.2e-43 146.3 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S19e DUF1772 PF08592.11 OAG40271.1 - 2.2e-22 79.9 0.3 3.3e-22 79.3 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) DUF2818 PF10993.8 OAG40272.1 - 0.0087 16.6 5.3 2.5 8.7 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF2818) DUF3413 PF11893.8 OAG40272.1 - 0.067 12.4 4.8 0.95 8.6 0.2 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF3413) Sec23_trunk PF04811.15 OAG40273.1 - 8e-74 248.3 0.0 1.6e-73 247.3 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 OAG40273.1 - 1.6e-23 82.5 0.0 6.1e-23 80.6 0.0 2.1 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 OAG40273.1 - 3.2e-17 63.1 0.0 6.9e-17 62.0 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 OAG40273.1 - 1.5e-16 60.2 4.7 2.6e-16 59.4 4.7 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 OAG40273.1 - 1.2e-07 31.5 0.0 2.7e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 OAG40273.1 - 0.037 13.4 0.1 0.079 12.4 0.1 1.4 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Pkinase PF00069.25 OAG40274.1 - 1.4e-67 227.8 0.0 1.7e-67 227.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG40274.1 - 3.6e-32 111.7 0.0 4.7e-32 111.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OAG40274.1 - 0.00034 20.0 0.2 0.00061 19.2 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OAG40274.1 - 0.004 16.2 0.4 0.0091 15.0 0.4 1.5 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 OAG40274.1 - 0.01 15.2 0.0 0.018 14.3 0.0 1.3 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 OAG40274.1 - 0.035 14.0 0.1 0.058 13.3 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family S_100 PF01023.19 OAG40274.1 - 0.04 13.6 0.1 0.12 12.1 0.1 1.8 1 0 0 1 1 1 0 S-100/ICaBP type calcium binding domain Seadorna_VP7 PF07387.11 OAG40274.1 - 0.062 12.4 0.1 0.09 11.8 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Epimerase PF01370.21 OAG40275.1 - 1.8e-15 57.0 0.0 3.7e-15 56.1 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 OAG40275.1 - 1.1e-13 51.5 0.0 2e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 OAG40275.1 - 1.6e-12 47.1 0.0 3.1e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 OAG40275.1 - 2.6e-12 46.8 0.0 3.9e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.17 OAG40275.1 - 1e-07 31.4 0.0 2.9e-06 26.6 0.0 2.7 1 1 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 OAG40275.1 - 1.9e-07 30.8 0.0 3.2e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 OAG40275.1 - 2.6e-05 23.5 0.0 0.33 10.1 0.0 3.2 1 1 2 3 3 3 3 Male sterility protein adh_short PF00106.25 OAG40275.1 - 0.00049 19.6 0.0 0.00098 18.6 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG40275.1 - 0.00083 19.0 0.0 0.0015 18.1 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.15 OAG40275.1 - 0.0034 16.6 0.0 0.0055 15.9 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 OAG40275.1 - 0.093 12.6 0.0 8.8 6.2 0.0 2.3 2 0 0 2 2 2 0 KR domain DUF2306 PF10067.9 OAG40276.1 - 6.4e-17 62.1 6.4 6.4e-17 62.1 6.4 2.0 2 0 0 2 2 2 1 Predicted membrane protein (DUF2306) DUF420 PF04238.12 OAG40276.1 - 0.078 13.3 0.2 0.078 13.3 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF420) Zn_clus PF00172.18 OAG40277.1 - 6.4e-07 29.4 9.4 1e-06 28.7 9.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 OAG40277.1 - 3.4e-05 22.8 0.1 0.00024 20.0 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF4290 PF14123.6 OAG40277.1 - 0.16 11.5 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4290) MFS_1 PF07690.16 OAG40278.1 - 2.4e-23 82.7 42.4 3.2e-23 82.2 42.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily ATF7IP_BD PF16788.5 OAG40279.1 - 4.2 7.4 4.7 6.7 6.7 4.7 1.2 1 0 0 1 1 1 0 ATF-interacting protein binding domain p450 PF00067.22 OAG40281.1 - 6.3e-62 209.8 0.0 8e-62 209.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DNA_pol_A_exo1 PF01612.20 OAG40283.1 - 2.1e-06 27.6 0.0 3.2e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease MuF_C PF18819.1 OAG40283.1 - 0.076 13.0 0.7 5.3 7.1 0.0 3.2 2 2 1 3 3 3 0 Phage MuF-C-terminal domain DUF4142 PF13628.6 OAG40283.1 - 0.12 12.6 0.0 0.22 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4142) Pkinase_Tyr PF07714.17 OAG40284.1 - 3.3e-07 29.9 0.0 5.2e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OAG40284.1 - 2.4e-06 27.1 0.0 9.3e-06 25.2 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Adaptin_N PF01602.20 OAG40285.1 - 7.2e-138 460.4 2.5 9.3e-138 460.0 2.5 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 OAG40285.1 - 2.3e-63 213.1 1.0 2.4e-61 206.5 0.4 2.7 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 OAG40285.1 - 3e-17 62.8 2.3 1.3e-07 31.8 0.0 6.0 4 2 3 7 7 7 4 HEAT repeats HEAT PF02985.22 OAG40285.1 - 1.2e-10 40.6 7.3 0.023 14.9 0.0 6.7 8 0 0 8 8 8 3 HEAT repeat RTP1_C1 PF10363.9 OAG40285.1 - 0.024 14.8 0.3 1.2 9.3 0.0 3.6 3 2 2 5 5 5 0 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 OAG40285.1 - 0.036 14.6 8.3 1 9.9 0.0 5.5 5 1 1 6 6 6 0 HEAT-like repeat CLASP_N PF12348.8 OAG40285.1 - 0.079 12.5 0.1 2.6 7.5 0.0 2.9 2 1 1 3 3 3 0 CLASP N terminal UNC45-central PF11701.8 OAG40285.1 - 0.11 12.4 0.3 0.58 10.1 0.1 2.4 2 1 0 2 2 2 0 Myosin-binding striated muscle assembly central CAAP1 PF15335.6 OAG40285.1 - 0.24 12.0 1.8 0.5 11.0 0.1 2.5 3 0 0 3 3 3 0 Caspase activity and apoptosis inhibitor 1 zf-CCCH_4 PF18044.1 OAG40286.1 - 1.5e-07 31.0 2.1 2.7e-07 30.2 2.1 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 OAG40286.1 - 5.3e-06 26.3 5.9 9.4e-06 25.5 5.9 1.4 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 OAG40286.1 - 0.00024 20.9 0.9 0.0004 20.2 0.9 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 OAG40286.1 - 0.86 10.2 4.9 1.8 9.1 4.9 1.6 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Ribosomal_S10 PF00338.22 OAG40287.1 - 4.5e-27 94.1 0.4 5.3e-27 93.9 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Xpo1 PF08389.12 OAG40288.1 - 8.9e-08 32.3 0.6 0.0013 18.8 0.1 3.9 4 0 0 4 4 4 2 Exportin 1-like protein CUE PF02845.16 OAG40288.1 - 1.8e-05 24.3 0.6 6.4e-05 22.6 0.2 2.2 2 0 0 2 2 2 1 CUE domain IBN_N PF03810.19 OAG40288.1 - 0.019 14.9 0.9 0.089 12.7 0.2 2.7 2 0 0 2 2 2 0 Importin-beta N-terminal domain DinB_2 PF12867.7 OAG40288.1 - 0.12 12.8 0.9 12 6.4 0.1 4.1 4 0 0 4 4 4 0 DinB superfamily GRIM-19 PF06212.12 OAG40289.1 - 1.8e-14 53.8 7.7 1.7e-10 41.0 0.0 2.7 2 1 1 3 3 3 2 GRIM-19 protein IMUP PF15761.5 OAG40289.1 - 0.64 10.7 0.1 0.64 10.7 0.1 2.6 3 0 0 3 3 3 0 Immortalisation up-regulated protein DUF4770 PF15994.5 OAG40289.1 - 0.68 10.1 14.0 0.79 9.9 10.3 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4770) DUF4834 PF16118.5 OAG40289.1 - 8.4 7.4 8.6 1.4 10.0 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) Presenilin PF01080.17 OAG40289.1 - 8.6 5.0 7.8 15 4.2 7.8 1.3 1 0 0 1 1 1 0 Presenilin DUF1688 PF07958.11 OAG40290.1 - 2.9e-152 507.2 0.0 3.3e-152 507.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) DUF2066 PF09839.9 OAG40290.1 - 0.18 11.2 0.2 2 7.7 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2066) GFO_IDH_MocA PF01408.22 OAG40291.1 - 6.8e-19 68.9 0.0 1.1e-18 68.2 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 OAG40291.1 - 0.0048 17.6 0.1 0.01 16.5 0.1 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain GFO_IDH_MocA_C PF02894.17 OAG40291.1 - 0.11 12.5 0.1 0.26 11.3 0.1 1.6 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain AA_permease_2 PF13520.6 OAG40293.1 - 2.7e-55 187.9 31.3 1.5e-54 185.5 31.3 1.8 1 1 0 1 1 1 1 Amino acid permease Ank_4 PF13637.6 OAG40295.1 - 3.1e-32 110.5 8.7 5.1e-14 52.5 0.0 7.0 2 2 5 7 7 7 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 OAG40295.1 - 4e-31 107.4 4.8 2.3e-11 44.1 0.0 4.9 3 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OAG40295.1 - 8.5e-27 92.9 11.5 7.9e-09 35.6 0.1 6.3 4 1 1 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 OAG40295.1 - 2e-23 81.7 15.7 3.9e-06 27.1 0.3 7.3 7 0 0 7 7 7 3 Ankyrin repeat Ank_3 PF13606.6 OAG40295.1 - 2.7e-20 70.3 12.7 5.6e-05 23.2 0.0 8.2 9 0 0 9 9 9 4 Ankyrin repeat Helo_like_N PF17111.5 OAG40295.1 - 1.7e-06 27.6 0.9 4.1e-06 26.3 0.9 1.7 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins YcgR PF07317.12 OAG40295.1 - 0.058 13.3 1.7 1.4 8.8 0.0 2.7 3 0 0 3 3 3 0 Flagellar regulator YcgR GAS PF13851.6 OAG40295.1 - 0.21 10.9 2.3 0.44 9.9 2.3 1.5 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Polysacc_deac_1 PF01522.21 OAG40296.1 - 9.4e-12 44.9 0.0 1.5e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase Oxidored_FMN PF00724.20 OAG40297.1 - 1.4e-70 238.2 0.0 2e-70 237.7 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DnaA_N PF11638.8 OAG40297.1 - 0.098 12.4 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 DnaA N-terminal domain Polysacc_deac_1 PF01522.21 OAG40298.1 - 4.4e-08 33.1 0.0 8.5e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Amidase PF01425.21 OAG40299.1 - 2e-80 271.0 0.0 2.6e-80 270.6 0.0 1.1 1 0 0 1 1 1 1 Amidase Aa_trans PF01490.18 OAG40300.1 - 1.5e-24 86.5 31.2 1.7e-24 86.3 31.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein SLATT_1 PF18181.1 OAG40300.1 - 1.1 9.2 8.8 3.3 7.6 0.9 3.5 3 0 0 3 3 3 0 SMODS and SLOG-associating 2TM effector domain 1 ArfGap PF01412.18 OAG40301.1 - 6.8e-41 139.0 0.4 9.7e-41 138.5 0.4 1.2 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf TSP9 PF11493.8 OAG40301.1 - 1.3 9.8 4.0 3 8.6 0.4 3.3 2 1 0 2 2 2 0 Thylakoid soluble phosphoprotein TSP9 Zds_C PF08632.10 OAG40302.1 - 1.7e-28 98.1 1.2 1.7e-28 98.1 1.2 2.1 2 0 0 2 2 2 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term DUF4349 PF14257.6 OAG40303.1 - 0.06 12.8 0.1 0.07 12.6 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) DUF2244 PF10003.9 OAG40303.1 - 0.13 11.9 1.5 0.18 11.5 1.5 1.2 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) TFIIE_alpha PF02002.17 OAG40304.1 - 2.3e-12 46.7 0.3 6.3e-12 45.3 0.0 1.9 2 0 0 2 2 2 1 TFIIE alpha subunit zinc-ribbons_6 PF07191.12 OAG40304.1 - 0.014 15.4 0.3 0.014 15.4 0.3 2.1 2 0 0 2 2 2 0 zinc-ribbons zf_UBZ PF18439.1 OAG40304.1 - 0.064 12.9 1.1 12 5.6 0.1 2.7 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Sirohm_synth_M PF14824.6 OAG40304.1 - 0.14 11.6 0.1 0.59 9.6 0.0 2.1 2 0 0 2 2 2 0 Sirohaem biosynthesis protein central GTP-bdg_M PF16360.5 OAG40304.1 - 1.3 9.7 5.4 1.8 9.2 0.2 3.0 3 0 0 3 3 3 0 GTP-binding GTPase Middle Region PhnA_Zn_Ribbon PF08274.12 OAG40304.1 - 2.1 8.4 7.5 3.4 7.7 0.9 2.7 2 0 0 2 2 2 0 PhnA Zinc-Ribbon zf-TFIIB PF13453.6 OAG40304.1 - 2.1 7.8 7.4 0.11 11.9 1.2 2.1 2 0 0 2 2 2 0 Transcription factor zinc-finger Tht1 PF04163.12 OAG40306.1 - 0.003 16.4 0.2 0.0083 14.9 0.2 1.7 1 1 0 1 1 1 1 Tht1-like nuclear fusion protein DUF713 PF05218.14 OAG40306.1 - 0.008 15.9 1.9 0.018 14.8 1.4 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF713) DUF1664 PF07889.12 OAG40306.1 - 0.029 14.4 2.9 1.8 8.7 0.7 3.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF948 PF06103.11 OAG40306.1 - 0.038 14.2 6.7 0.72 10.2 0.1 4.1 2 1 2 4 4 4 0 Bacterial protein of unknown function (DUF948) Baculo_PEP_C PF04513.12 OAG40306.1 - 0.05 13.6 11.2 0.46 10.5 1.2 3.6 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Sec8_exocyst PF04048.14 OAG40306.1 - 0.056 13.3 2.1 3.8 7.4 0.3 2.9 2 1 0 2 2 2 0 Sec8 exocyst complex component specific domain Helicase_PWI PF18149.1 OAG40306.1 - 0.18 12.0 3.1 0.34 11.1 1.2 2.3 2 0 0 2 2 2 0 N-terminal helicase PWI domain DUF3347 PF11827.8 OAG40306.1 - 0.34 11.1 3.0 0.97 9.6 3.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) CENP-H PF05837.12 OAG40306.1 - 0.96 9.9 16.3 9.7 6.6 5.0 3.5 2 1 1 3 3 3 0 Centromere protein H (CENP-H) DUF4618 PF15397.6 OAG40306.1 - 2.3 7.6 10.8 0.32 10.4 6.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) Neurensin PF14927.6 OAG40308.1 - 0.1 12.3 0.3 0.32 10.7 0.1 1.9 2 0 0 2 2 2 0 Neurensin DUF3185 PF11381.8 OAG40308.1 - 0.32 11.0 0.0 0.32 11.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) SIR2 PF02146.17 OAG40309.1 - 4.3e-38 131.0 0.0 2.5e-37 128.5 0.0 1.9 1 1 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 OAG40309.1 - 0.016 15.0 0.1 0.25 11.1 0.0 2.2 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Flavoprotein PF02441.19 OAG40310.1 - 0.0003 20.6 0.0 0.00059 19.6 0.0 1.4 1 0 0 1 1 1 1 Flavoprotein DUF3517 PF12030.8 OAG40311.1 - 1.2e-60 205.2 0.7 3.9e-60 203.6 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3517) UCH PF00443.29 OAG40311.1 - 1.1e-40 139.8 0.3 1.9e-40 139.0 0.3 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OAG40311.1 - 5.2e-25 88.7 0.1 1.3e-24 87.3 0.1 1.8 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ADD_ATRX PF17981.1 OAG40311.1 - 0.11 12.3 0.1 0.39 10.6 0.1 1.8 1 0 0 1 1 1 0 Cysteine Rich ADD domain RNase_P_pop3 PF08228.11 OAG40312.1 - 8.7e-10 38.9 0.0 1.3e-08 35.1 0.0 2.5 2 1 0 2 2 2 1 RNase P subunit Pop3 ICMT PF04140.14 OAG40313.1 - 5.5e-28 97.2 1.0 1e-27 96.4 1.0 1.4 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 OAG40313.1 - 9e-13 48.5 0.8 9e-13 48.5 0.8 1.7 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.12 OAG40313.1 - 4.7e-06 26.3 2.3 6.3e-06 25.9 2.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ERG4_ERG24 PF01222.17 OAG40313.1 - 5.7e-05 22.1 1.6 8.1e-05 21.6 1.6 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Hexapep_2 PF14602.6 OAG40314.1 - 8.2e-13 47.9 5.6 8.3e-09 35.1 3.6 2.4 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.24 OAG40314.1 - 1.7e-12 46.5 6.3 1.8e-10 40.1 3.5 2.6 3 0 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Mac PF12464.8 OAG40314.1 - 3.9e-09 36.6 0.0 7.2e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Maltose acetyltransferase GST_N_4 PF17172.4 OAG40315.1 - 4.7e-18 65.8 0.0 9.5e-18 64.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 OAG40315.1 - 2.5e-08 33.6 0.0 4.6e-07 29.5 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OAG40315.1 - 4e-05 23.6 0.0 6.9e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 OAG40315.1 - 0.013 15.9 0.0 0.058 13.8 0.0 2.0 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Tom37 PF10568.9 OAG40315.1 - 0.16 12.3 0.0 0.36 11.1 0.0 1.6 2 0 0 2 2 2 0 Outer mitochondrial membrane transport complex protein ChitinaseA_N PF08329.10 OAG40316.1 - 5.1 6.7 6.6 8.9 6.0 6.6 1.4 1 0 0 1 1 1 0 Chitinase A, N-terminal domain Rax2 PF12768.7 OAG40317.1 - 0.0012 18.4 0.0 0.0016 17.9 0.0 1.2 1 0 0 1 1 1 1 Cortical protein marker for cell polarity Gram_pos_anchor PF00746.21 OAG40317.1 - 0.0074 16.2 2.9 0.042 13.8 0.9 2.5 2 0 0 2 2 2 1 LPXTG cell wall anchor motif DUF5349 PF17298.2 OAG40317.1 - 0.48 10.1 4.4 0.77 9.5 4.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5349) Sugar_tr PF00083.24 OAG40318.1 - 2.2e-122 409.2 24.0 2.6e-122 409.0 24.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG40318.1 - 3.7e-25 88.6 33.3 6e-19 68.2 8.8 2.4 2 1 1 3 3 3 2 Major Facilitator Superfamily MFS_3 PF05977.13 OAG40318.1 - 0.041 12.3 6.9 0.028 12.8 0.7 2.8 2 1 1 3 3 3 0 Transmembrane secretion effector Hydrolase_like PF13242.6 OAG40319.1 - 0.00031 20.7 0.0 0.00057 19.9 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.6 OAG40319.1 - 0.00037 20.6 0.0 0.00054 20.1 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Acid_PPase PF12689.7 OAG40319.1 - 0.14 12.0 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Acid Phosphatase FIIND PF13553.6 OAG40319.1 - 0.14 11.5 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Function to find FTA4 PF13093.6 OAG40320.1 - 2.1e-50 171.4 1.7 2.6e-50 171.1 1.7 1.1 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DUF4569 PF15133.6 OAG40320.1 - 0.012 15.3 0.0 0.018 14.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) DUF4200 PF13863.6 OAG40320.1 - 0.3 11.5 0.2 0.3 11.5 0.2 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) Cyclin_N2 PF16500.5 OAG40320.1 - 0.47 11.2 3.1 0.3 11.8 0.7 1.8 2 0 0 2 2 2 0 N-terminal region of cyclin_N Sec62 PF03839.16 OAG40321.1 - 1.2e-75 253.7 5.2 1.2e-75 253.7 5.2 1.9 2 0 0 2 2 2 1 Translocation protein Sec62 MPM1 PF17234.2 OAG40321.1 - 0.033 14.5 1.3 0.3 11.3 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 DUF2207 PF09972.9 OAG40321.1 - 0.048 12.4 0.1 0.1 11.3 0.1 1.6 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) UvrD_C PF13361.6 OAG40321.1 - 0.09 12.1 0.0 0.092 12.1 0.0 1.1 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Lectin_C PF00059.21 OAG40322.1 - 0.02 15.6 0.1 0.054 14.2 0.1 1.7 1 0 0 1 1 1 0 Lectin C-type domain TMEM154 PF15102.6 OAG40322.1 - 0.084 12.8 0.0 0.084 12.8 0.0 2.4 2 1 1 3 3 3 0 TMEM154 protein family NmrA PF05368.13 OAG40323.1 - 6.1e-27 94.7 0.2 7.1e-27 94.5 0.2 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG40323.1 - 2e-18 67.0 0.0 3e-18 66.4 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAG40323.1 - 1.7e-06 27.7 0.2 5.8e-06 25.9 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OAG40323.1 - 2.7e-05 23.3 0.0 4.8e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Sacchrp_dh_NADP PF03435.18 OAG40323.1 - 4.5e-05 23.7 0.4 0.00082 19.6 0.0 2.1 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain DapB_N PF01113.20 OAG40323.1 - 0.00064 19.8 0.5 0.0014 18.7 0.1 1.8 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.24 OAG40323.1 - 0.00094 19.6 0.5 0.0043 17.5 0.1 2.1 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.17 OAG40323.1 - 0.026 13.6 0.1 0.052 12.6 0.1 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain DXP_reductoisom PF02670.16 OAG40323.1 - 0.048 14.4 0.4 0.82 10.4 0.2 2.2 2 0 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase adh_short PF00106.25 OAG40323.1 - 0.073 12.5 0.7 0.17 11.3 0.1 1.8 2 0 0 2 2 2 0 short chain dehydrogenase Shikimate_DH PF01488.20 OAG40323.1 - 0.11 12.6 0.1 0.35 10.9 0.0 1.9 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase CENP-B_dimeris PF09026.10 OAG40324.1 - 0.074 13.4 10.4 0.29 11.5 8.8 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain K_channel_TID PF07941.11 OAG40324.1 - 0.27 11.7 5.5 1.1 9.7 5.5 2.1 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain DNA_pol_phi PF04931.13 OAG40324.1 - 5.3 5.0 7.0 7.5 4.5 7.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi Cwf_Cwc_15 PF04889.12 OAG40324.1 - 5.7 6.6 7.3 14 5.3 7.3 1.6 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Abhydrolase_3 PF07859.13 OAG40325.1 - 1.9e-21 76.9 0.0 2.8e-21 76.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 OAG40325.1 - 3.8e-16 58.9 0.0 5.9e-16 58.3 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase DUF2974 PF11187.8 OAG40325.1 - 0.037 13.6 0.0 0.063 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Pkinase PF00069.25 OAG40327.1 - 4.8e-67 226.1 0.0 6.1e-67 225.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG40327.1 - 1.4e-31 109.8 0.0 1.7e-31 109.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OAG40327.1 - 1.2e-05 24.5 0.1 1.6e-05 24.1 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OAG40327.1 - 7.5e-05 22.2 0.1 0.00026 20.4 0.1 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OAG40327.1 - 0.00048 20.1 0.1 0.0014 18.6 0.0 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 OAG40327.1 - 0.00055 19.3 0.0 0.058 12.7 0.0 2.2 1 1 1 2 2 2 2 Kinase-like FTA2 PF13095.6 OAG40327.1 - 0.014 15.1 0.0 0.023 14.3 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 OAG40327.1 - 0.028 14.0 0.0 0.048 13.3 0.0 1.4 1 0 0 1 1 1 0 RIO1 family G-alpha PF00503.20 OAG40328.1 - 2.9e-117 391.8 0.3 3.3e-117 391.6 0.3 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 OAG40328.1 - 4.2e-15 55.6 1.2 2.2e-10 40.3 0.3 2.5 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OAG40328.1 - 1.1e-05 24.9 0.1 0.063 12.6 0.0 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 OAG40328.1 - 0.0019 18.4 0.2 0.56 10.4 0.1 2.6 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase MCM PF00493.23 OAG40328.1 - 0.068 12.3 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain TniB PF05621.11 OAG40328.1 - 0.069 12.6 0.1 0.12 11.7 0.1 1.4 1 0 0 1 1 1 0 Bacterial TniB protein AAA_29 PF13555.6 OAG40328.1 - 0.095 12.5 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Phosphorylase PF00343.20 OAG40329.1 - 0 1073.9 0.0 0 1073.7 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase Avl9 PF09794.9 OAG40330.1 - 5.3e-131 436.8 0.0 7e-131 436.4 0.0 1.1 1 0 0 1 1 1 1 Transport protein Avl9 SPA PF08616.10 OAG40330.1 - 3.5e-07 30.2 0.1 0.001 19.0 0.0 2.4 2 0 0 2 2 2 2 Stabilization of polarity axis DUF2347 PF09804.9 OAG40330.1 - 9.2e-05 22.2 0.2 0.0004 20.0 0.0 2.3 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2347) Cullin PF00888.22 OAG40331.1 - 7.7e-194 645.8 10.3 9.8e-194 645.4 10.3 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 OAG40331.1 - 5.3e-25 87.2 4.7 6.3e-25 87.0 2.5 2.4 2 0 0 2 2 2 1 Cullin protein neddylation domain HTH_34 PF13601.6 OAG40331.1 - 0.043 14.0 0.0 0.59 10.3 0.0 2.8 2 1 0 2 2 2 0 Winged helix DNA-binding domain SatD PF16264.5 OAG40331.1 - 0.047 13.3 0.4 0.21 11.1 0.0 2.2 2 0 0 2 2 2 0 SatD family (SatD) Cupin_1 PF00190.22 OAG40332.1 - 2.8e-06 27.0 0.2 4e-06 26.5 0.2 1.2 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 OAG40332.1 - 3.4e-05 23.5 0.3 6.1e-05 22.7 0.3 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.7 OAG40332.1 - 0.011 15.5 0.0 0.013 15.2 0.0 1.2 1 0 0 1 1 1 0 Cupin ARD PF03079.14 OAG40332.1 - 0.04 14.1 0.0 0.058 13.6 0.0 1.2 1 0 0 1 1 1 0 ARD/ARD' family HupF_HypC PF01455.18 OAG40332.1 - 0.083 13.1 0.1 0.29 11.3 0.0 1.8 2 0 0 2 2 2 0 HupF/HypC family Mit_KHE1 PF10173.9 OAG40334.1 - 6.6e-60 202.5 0.8 7e-60 202.4 0.1 1.4 2 0 0 2 2 2 1 Mitochondrial K+-H+ exchange-related DSPc PF00782.20 OAG40335.1 - 4.2e-13 49.3 0.0 6e-13 48.8 0.0 1.4 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain B3_4 PF03483.17 OAG40335.1 - 0.17 11.5 0.0 0.27 10.9 0.0 1.2 1 0 0 1 1 1 0 B3/4 domain zf-UBR PF02207.20 OAG40337.1 - 2.1e-13 50.3 3.8 2.1e-13 50.3 3.8 3.5 4 0 0 4 4 4 2 Putative zinc finger in N-recognin (UBR box) MCM PF00493.23 OAG40338.1 - 2.7e-101 337.4 0.0 4.2e-101 336.7 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 OAG40338.1 - 1.8e-38 131.2 0.4 3.2e-38 130.4 0.4 1.4 1 0 0 1 1 1 1 MCM OB domain MCM2_N PF12619.8 OAG40338.1 - 2.6e-34 118.7 35.4 2.6e-34 118.7 35.4 2.4 2 1 0 2 2 2 1 Mini-chromosome maintenance protein 2 MCM_lid PF17855.1 OAG40338.1 - 6.2e-25 87.4 0.5 1.8e-24 86.0 0.5 1.9 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 OAG40338.1 - 1.3e-14 54.7 0.0 3.5e-14 53.2 0.0 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 OAG40338.1 - 2.7e-08 33.4 0.1 1.8e-06 27.5 0.0 2.4 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 OAG40338.1 - 2.4e-06 27.6 0.0 5.9e-06 26.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 OAG40338.1 - 0.0017 18.1 0.2 0.012 15.3 0.2 2.1 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.11 OAG40338.1 - 0.0078 16.1 0.1 0.11 12.4 0.0 2.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OAG40338.1 - 0.12 12.7 0.5 0.61 10.4 0.3 2.5 2 1 0 2 2 1 0 AAA ATPase domain Ribosomal_L9_N PF01281.19 OAG40338.1 - 0.12 11.9 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L9, N-terminal domain Zn_ribbon_2 PF12674.7 OAG40338.1 - 0.12 13.0 0.4 0.34 11.6 0.4 1.8 1 0 0 1 1 1 0 Putative zinc ribbon domain SelR PF01641.18 OAG40338.1 - 0.18 11.9 0.1 7.4 6.7 0.1 2.4 2 0 0 2 2 2 0 SelR domain DUF1272 PF06906.11 OAG40338.1 - 0.21 11.7 0.5 0.44 10.7 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) DZR PF12773.7 OAG40338.1 - 0.23 11.5 0.8 0.51 10.4 0.8 1.5 1 0 0 1 1 1 0 Double zinc ribbon SNF2_N PF00176.23 OAG40339.1 - 1e-61 208.6 0.0 1e-61 208.6 0.0 1.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OAG40339.1 - 3.9e-23 81.9 0.7 3.6e-22 78.8 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG40339.1 - 1.3e-08 35.0 0.8 3.9e-08 33.5 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 OAG40339.1 - 0.00059 19.6 0.0 0.002 17.9 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 OAG40339.1 - 0.00095 18.4 0.0 0.00095 18.4 0.0 2.0 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase Glyco_hydro_31 PF01055.26 OAG40340.1 - 4.1e-107 359.1 0.4 1.2e-106 357.6 0.4 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 31 DUF4968 PF16338.5 OAG40340.1 - 3.2e-06 27.3 0.0 6.1e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4968) NACHT PF05729.12 OAG40340.1 - 9.6e-05 22.4 0.1 0.00046 20.1 0.1 2.3 1 1 0 1 1 1 1 NACHT domain Gal_mutarotas_2 PF13802.6 OAG40340.1 - 0.00011 22.4 0.1 0.00045 20.5 0.1 2.0 1 1 0 1 1 1 1 Galactose mutarotase-like Rogdi_lz PF10259.9 OAG40340.1 - 0.036 13.5 1.2 0.075 12.5 1.2 1.5 1 0 0 1 1 1 0 Rogdi leucine zipper containing protein Sulfate_transp PF00916.20 OAG40341.1 - 1.3e-80 271.0 15.8 1.7e-80 270.7 15.8 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 OAG40341.1 - 1.3e-14 53.9 0.0 2.4e-14 53.0 0.0 1.5 1 0 0 1 1 1 1 STAS domain MotB_plug PF13677.6 OAG40341.1 - 0.0014 18.2 0.7 0.0038 16.8 0.7 1.7 1 0 0 1 1 1 1 Membrane MotB of proton-channel complex MotA/MotB STAS_2 PF13466.6 OAG40341.1 - 0.04 14.3 0.0 0.15 12.4 0.0 1.9 1 1 0 1 1 1 0 STAS domain DUF1275 PF06912.11 OAG40342.1 - 3.9e-45 154.2 8.0 4.5e-45 153.9 8.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) DUF2568 PF10823.8 OAG40342.1 - 1.8 8.9 6.3 2.4 8.5 2.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2568) TLP1_add_C PF18313.1 OAG40343.1 - 2.1e-29 101.3 0.2 5.4e-29 100.0 0.1 1.7 2 0 0 2 2 2 1 Thiolase-like protein type 1 additional C-terminal domain SOG2 PF10428.9 OAG40344.1 - 0.0096 15.2 9.7 0.011 15.0 9.7 1.2 1 0 0 1 1 1 1 RAM signalling pathway protein Mucin PF01456.17 OAG40344.1 - 0.037 14.0 26.9 0.083 12.9 26.9 1.7 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF4834 PF16118.5 OAG40344.1 - 0.31 12.0 3.4 3.9 8.5 3.4 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) Shisa PF13908.6 OAG40344.1 - 0.65 10.2 12.8 1.8 8.8 12.8 1.8 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator PRCC PF10253.9 OAG40344.1 - 1.2 9.9 10.0 0.12 13.2 5.0 1.8 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting Hamartin PF04388.12 OAG40344.1 - 5.4 5.5 9.3 5.8 5.5 9.3 1.1 1 0 0 1 1 1 0 Hamartin protein Aconitase PF00330.20 OAG40345.1 - 1.9 7.4 4.2 4.6 6.1 1.8 2.0 2 0 0 2 2 2 0 Aconitase family (aconitate hydratase) TatD_DNase PF01026.21 OAG40346.1 - 8e-36 123.7 0.0 1.7e-35 122.6 0.0 1.5 1 1 0 1 1 1 1 TatD related DNase DUF2014 PF09427.10 OAG40347.1 - 6.4e-89 297.8 0.2 1.1e-88 297.0 0.0 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF2014) HLH PF00010.26 OAG40347.1 - 9.4e-19 67.1 0.7 2.1e-18 66.0 0.7 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain bZIP_1 PF00170.21 OAG40347.1 - 0.00034 20.6 1.7 0.00056 20.0 0.7 1.9 2 0 0 2 2 2 1 bZIP transcription factor ZapB PF06005.12 OAG40347.1 - 0.011 16.1 0.3 0.011 16.1 0.3 2.3 2 0 0 2 2 2 0 Cell division protein ZapB bZIP_2 PF07716.15 OAG40347.1 - 0.61 10.2 3.9 0.65 10.1 1.6 2.1 2 0 0 2 2 2 0 Basic region leucine zipper Nnf1 PF03980.14 OAG40347.1 - 2 8.8 7.4 0.63 10.4 3.2 2.5 2 0 0 2 2 2 0 Nnf1 ABC_trans_aux PF03886.13 OAG40348.1 - 0.063 12.9 0.3 0.089 12.4 0.3 1.2 1 0 0 1 1 1 0 ABC-type transport auxiliary lipoprotein component Anp1 PF03452.14 OAG40349.1 - 2.2e-105 351.8 0.0 2.6e-105 351.6 0.0 1.1 1 0 0 1 1 1 1 Anp1 DUF4245 PF14030.6 OAG40349.1 - 0.059 13.4 0.0 0.34 10.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4245) Peptidase_S10 PF00450.22 OAG40350.1 - 1.8e-83 281.3 2.5 5.5e-83 279.7 2.5 1.7 1 1 0 1 1 1 1 Serine carboxypeptidase HhH-GPD PF00730.25 OAG40351.1 - 0.00028 21.3 0.0 0.00054 20.4 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein DSPc PF00782.20 OAG40352.1 - 4.5e-22 78.3 0.0 6.5e-22 77.8 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 OAG40352.1 - 0.0022 18.3 0.0 0.0038 17.5 0.0 1.4 1 0 0 1 1 1 1 Rit1 DUSP-like domain Y_phosphatase PF00102.27 OAG40352.1 - 0.0034 17.0 0.0 0.0042 16.7 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Nop16 PF09420.10 OAG40353.1 - 5.3e-66 222.6 10.9 6e-66 222.5 10.9 1.0 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 DUF5024 PF16427.5 OAG40353.1 - 0.058 13.7 0.5 0.14 12.5 0.0 1.8 2 1 0 2 2 2 0 Domain of unknown function (DUF5024) DUF1059 PF06348.11 OAG40353.1 - 0.13 12.5 0.6 0.28 11.4 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1059) UPF0564 PF10595.9 OAG40353.1 - 0.36 9.8 11.2 0.17 10.9 3.5 2.0 2 0 0 2 2 2 0 Uncharacterised protein family UPF0564 Zip PF02535.22 OAG40354.1 - 1.8e-62 211.5 11.2 2.5e-50 171.6 4.1 2.1 1 1 1 2 2 2 2 ZIP Zinc transporter Phage_holin_Dp1 PF16938.5 OAG40354.1 - 0.065 13.4 0.7 2 8.7 0.3 2.8 2 0 0 2 2 2 0 Putative phage holin Dp-1 Gly-zipper_YMGG PF13441.6 OAG40354.1 - 2.5 7.9 17.6 0.22 11.3 11.9 2.3 2 0 0 2 2 2 0 YMGG-like Gly-zipper Aldedh PF00171.22 OAG40355.1 - 1.4e-116 389.7 0.0 2.1e-116 389.2 0.0 1.2 1 0 0 1 1 1 1 Aldehyde dehydrogenase family NAD_binding_10 PF13460.6 OAG40355.1 - 8.9e-07 29.0 0.3 1.3e-05 25.2 0.3 2.4 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 OAG40355.1 - 0.0035 16.9 0.5 0.0071 15.9 0.5 1.5 1 0 0 1 1 1 1 NmrA-like family RdRP PF05183.12 OAG40356.1 - 6.1e-111 371.9 0.0 9.3e-111 371.3 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase AAA_11 PF13086.6 OAG40356.1 - 1e-40 140.2 3.4 4.3e-21 75.9 1.3 2.3 1 1 1 2 2 2 2 AAA domain AAA_12 PF13087.6 OAG40356.1 - 1.5e-26 93.3 0.0 4.6e-26 91.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 OAG40356.1 - 3.2e-14 53.1 0.4 9.7e-14 51.5 0.2 1.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 OAG40356.1 - 6.4e-12 46.0 0.3 1.8e-11 44.6 0.3 1.8 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 OAG40356.1 - 2.9e-06 27.4 0.0 6.6e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PhoH PF02562.16 OAG40356.1 - 3.1e-05 23.5 0.0 0.00013 21.5 0.0 2.1 1 1 0 1 1 1 1 PhoH-like protein Helicase_RecD PF05127.14 OAG40356.1 - 4.8e-05 23.3 0.0 0.00012 22.0 0.0 1.6 1 0 0 1 1 1 1 Helicase AAA_22 PF13401.6 OAG40356.1 - 0.0012 19.1 0.0 0.0034 17.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 OAG40356.1 - 0.0021 17.7 0.0 0.0081 15.7 0.0 1.8 1 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA PF00004.29 OAG40356.1 - 0.01 16.3 0.0 0.029 14.8 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 OAG40356.1 - 0.013 15.9 0.0 0.038 14.4 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_16 PF13191.6 OAG40356.1 - 0.018 15.4 0.0 0.059 13.8 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.14 OAG40356.1 - 0.083 12.9 0.0 0.22 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 OAG40357.1 - 1.8e-27 96.6 0.0 2.2e-27 96.3 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OAG40357.1 - 0.0008 19.8 0.0 0.0011 19.4 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 OAG40357.1 - 0.0038 17.8 0.0 0.0059 17.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 OAG40357.1 - 0.0078 16.5 0.0 0.013 15.7 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 OAG40357.1 - 0.026 14.9 0.0 0.082 13.3 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MobB PF03205.14 OAG40357.1 - 0.058 13.3 0.0 0.094 12.6 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.6 OAG40357.1 - 0.085 13.0 0.0 0.18 11.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 OAG40357.1 - 0.11 12.3 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein MMR_HSR1 PF01926.23 OAG40357.1 - 0.12 12.5 0.0 0.81 9.8 0.0 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase Cu-oxidase_3 PF07732.15 OAG40359.1 - 5.2e-43 145.8 5.8 4.8e-41 139.5 2.5 2.6 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 OAG40359.1 - 9.5e-42 142.0 6.1 1.7e-39 134.7 0.1 3.5 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 OAG40359.1 - 1.6e-34 119.3 0.0 6e-34 117.5 0.0 2.0 1 0 0 1 1 1 1 Multicopper oxidase Mt_ATP-synt_D PF05873.12 OAG40360.1 - 3.7e-17 62.6 0.3 4.5e-17 62.3 0.3 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) Dor1 PF04124.12 OAG40360.1 - 0.022 13.4 0.4 0.027 13.1 0.4 1.1 1 0 0 1 1 1 0 Dor1-like family BLOC1_2 PF10046.9 OAG40360.1 - 0.082 13.2 1.7 0.47 10.8 0.6 2.4 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 BORCS8 PF10167.9 OAG40360.1 - 0.097 12.6 0.2 0.18 11.7 0.2 1.6 1 1 0 1 1 1 0 BLOC-1-related complex sub-unit 8 E3_UbLigase_R4 PF13764.6 OAG40360.1 - 0.11 10.6 0.0 0.13 10.4 0.0 1.0 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase UBR4 NAC PF01849.18 OAG40361.1 - 1.6e-22 79.2 0.0 6.8e-22 77.2 0.0 1.9 2 0 0 2 2 2 1 NAC domain Pes-10 PF07149.11 OAG40361.1 - 0.045 12.8 6.6 0.071 12.2 6.6 1.3 1 0 0 1 1 1 0 Pes-10 Myc_N PF01056.18 OAG40361.1 - 2 8.2 8.8 3.3 7.5 8.8 1.5 1 1 0 1 1 1 0 Myc amino-terminal region CFIA_Pcf11 PF11526.8 OAG40361.1 - 4 8.0 6.8 1.6 9.3 1.0 2.6 2 1 1 3 3 3 0 Subunit of cleavage factor IA Pcf11 Ribosomal_L14e PF01929.17 OAG40362.1 - 2.4e-31 108.1 2.5 3.6e-31 107.5 2.5 1.3 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.29 OAG40362.1 - 2.6e-05 24.0 0.2 5e-05 23.1 0.2 1.5 1 0 0 1 1 1 1 KOW motif Prot_ATP_ID_OB PF16450.5 OAG40362.1 - 0.0067 16.4 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain RGS PF00615.19 OAG40363.1 - 0.008 16.4 0.0 0.053 13.8 0.0 2.1 1 1 0 1 1 1 1 Regulator of G protein signaling domain Methyltransf_11 PF08241.12 OAG40364.1 - 3.7e-16 59.6 0.0 7.5e-16 58.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG40364.1 - 7.3e-16 58.7 0.0 2.2e-15 57.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAG40364.1 - 2e-13 50.5 0.0 3.2e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG40364.1 - 2.8e-13 49.9 0.0 4e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Sterol_MT_C PF08498.10 OAG40364.1 - 1.3e-10 41.4 0.0 2.6e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal CMAS PF02353.20 OAG40364.1 - 6.9e-10 38.7 0.0 9.7e-10 38.2 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 OAG40364.1 - 4.9e-07 30.4 0.0 1e-06 29.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAG40364.1 - 0.00011 21.7 0.0 0.00017 21.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 OAG40364.1 - 0.0036 17.1 0.0 0.0056 16.5 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_15 PF09445.10 OAG40364.1 - 0.065 12.8 0.0 0.095 12.3 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase GTP_EFTU PF00009.27 OAG40365.1 - 1.2e-66 224.0 0.1 1.7e-66 223.5 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 OAG40365.1 - 5e-32 110.2 0.0 1.6e-31 108.6 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 OAG40365.1 - 1.5e-21 76.2 0.0 1.3e-20 73.2 0.0 2.3 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 OAG40365.1 - 6.6e-14 52.1 0.0 2.9e-13 50.0 0.0 2.2 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 OAG40365.1 - 6.3e-12 45.4 0.0 1.4e-11 44.3 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 OAG40365.1 - 0.00017 21.6 0.2 0.00049 20.2 0.1 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase Solute_trans_a PF03619.16 OAG40366.1 - 8.9e-98 327.0 12.6 1.1e-97 326.7 12.6 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha CAML PF14963.6 OAG40366.1 - 8.9 6.3 5.7 15 5.6 5.7 1.3 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand MFS_1 PF07690.16 OAG40368.1 - 8.5e-44 149.9 24.5 8.5e-44 149.9 24.5 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG40368.1 - 7.7e-10 38.2 18.1 4.7e-09 35.6 18.1 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 OAG40368.1 - 1.4e-08 33.6 1.2 2.1e-08 33.1 1.2 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2178 PF09946.9 OAG40368.1 - 6.9 6.9 8.3 5.8 7.1 0.2 3.5 4 0 0 4 4 4 0 Predicted membrane protein (DUF2178) Rick_17kDa_Anti PF05433.15 OAG40369.1 - 2.1e-05 24.3 19.7 0.00021 21.1 11.8 1.8 1 1 1 2 2 2 2 Glycine zipper 2TM domain Ses_B PF17046.5 OAG40369.1 - 0.12 12.4 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 SesB domain on fungal death-pathway protein ATPase_gene1 PF09527.10 OAG40369.1 - 0.64 10.2 2.7 0.94 9.7 2.7 1.2 1 0 0 1 1 1 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter Bacteriocin_IIc PF10439.9 OAG40369.1 - 0.97 9.6 6.5 1.6 8.9 6.5 1.3 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Gly-zipper_YMGG PF13441.6 OAG40369.1 - 1 9.1 9.9 2.1 8.2 9.9 1.5 1 0 0 1 1 1 0 YMGG-like Gly-zipper ABC_tran PF00005.27 OAG40370.1 - 1.6e-47 161.4 0.3 1.3e-23 84.0 0.0 4.0 2 2 0 2 2 2 2 ABC transporter 4HB PF17947.1 OAG40370.1 - 7.9e-30 102.7 2.2 2.3e-29 101.2 2.2 1.9 1 0 0 1 1 1 1 Four helical bundle domain AAA_21 PF13304.6 OAG40370.1 - 3.4e-16 59.9 0.1 0.0022 17.8 0.0 5.1 4 1 0 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OAG40370.1 - 1.3e-15 57.4 0.0 1.8e-06 27.6 0.0 3.5 2 1 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 OAG40370.1 - 6.1e-11 43.2 3.7 3.9e-05 24.2 0.1 3.8 4 0 0 4 4 3 2 AAA domain AAA_29 PF13555.6 OAG40370.1 - 3.8e-09 36.2 0.2 0.0025 17.5 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 OAG40370.1 - 2.1e-07 31.0 0.0 0.001 19.0 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OAG40370.1 - 1.1e-06 28.8 0.1 0.0061 16.6 0.0 3.0 3 0 0 3 3 2 2 50S ribosome-binding GTPase AAA_28 PF13521.6 OAG40370.1 - 3.6e-06 27.3 0.0 0.037 14.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 OAG40370.1 - 7.4e-06 26.4 0.1 0.11 12.9 0.0 3.4 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 OAG40370.1 - 1.1e-05 25.7 0.2 0.23 11.7 0.0 3.8 5 0 0 5 5 3 2 AAA domain AAA_18 PF13238.6 OAG40370.1 - 2.2e-05 25.0 0.1 0.67 10.5 0.0 3.4 3 0 0 3 3 2 2 AAA domain DUF87 PF01935.17 OAG40370.1 - 2.7e-05 24.4 0.0 0.17 12.0 0.0 3.5 2 1 1 3 3 3 1 Helicase HerA, central domain AAA PF00004.29 OAG40370.1 - 3.7e-05 24.2 0.3 0.79 10.1 0.0 4.4 4 1 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.9 OAG40370.1 - 3.9e-05 23.4 0.0 0.07 12.9 0.0 2.9 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.23 OAG40370.1 - 0.00012 22.2 0.1 0.0037 17.3 0.0 2.8 2 0 0 2 2 2 1 Dynamin family AAA_27 PF13514.6 OAG40370.1 - 0.00014 21.6 0.0 0.098 12.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 OAG40370.1 - 0.00017 21.5 0.0 0.11 12.4 0.0 2.5 2 0 0 2 2 2 1 NACHT domain RNA_helicase PF00910.22 OAG40370.1 - 0.0003 21.1 0.0 0.81 10.1 0.0 2.7 2 0 0 2 2 2 1 RNA helicase MeaB PF03308.16 OAG40370.1 - 0.00039 19.5 0.1 0.59 9.1 0.0 2.5 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_33 PF13671.6 OAG40370.1 - 0.00043 20.5 0.0 0.57 10.3 0.0 3.0 3 0 0 3 3 2 1 AAA domain G-alpha PF00503.20 OAG40370.1 - 0.00059 19.1 0.1 0.78 8.8 0.0 2.7 3 0 0 3 3 2 2 G-protein alpha subunit AAA_15 PF13175.6 OAG40370.1 - 0.00074 19.3 3.4 0.92 9.1 0.9 3.4 2 2 1 3 3 3 2 AAA ATPase domain AAA_24 PF13479.6 OAG40370.1 - 0.00081 19.2 0.0 1.6 8.4 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 OAG40370.1 - 0.0021 17.8 0.0 2.7 7.7 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.6 OAG40370.1 - 0.0025 17.9 0.0 5.8 7.0 0.0 3.3 3 0 0 3 3 3 0 AAA domain SbcCD_C PF13558.6 OAG40370.1 - 0.0077 16.4 0.0 1.5 9.1 0.0 3.0 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit ATP_bind_1 PF03029.17 OAG40370.1 - 0.0079 16.0 0.0 4 7.2 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein CLP1_P PF16575.5 OAG40370.1 - 0.011 15.5 0.0 0.63 9.8 0.0 2.7 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop FtsK_SpoIIIE PF01580.18 OAG40370.1 - 0.012 14.9 0.8 5.4 6.3 0.0 3.2 3 0 0 3 3 3 0 FtsK/SpoIIIE family Roc PF08477.13 OAG40370.1 - 0.012 15.8 0.0 8.9 6.6 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NB-ARC PF00931.22 OAG40370.1 - 0.013 14.7 0.1 0.45 9.7 0.0 2.6 2 0 0 2 2 2 0 NB-ARC domain cobW PF02492.19 OAG40370.1 - 0.016 14.8 0.0 12 5.5 0.0 3.1 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain ATPase_2 PF01637.18 OAG40370.1 - 0.022 14.7 0.1 3.8 7.4 0.0 3.1 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea Rad17 PF03215.15 OAG40370.1 - 0.025 14.5 0.0 1.7 8.5 0.0 2.5 2 0 0 2 2 2 0 Rad17 P-loop domain IstB_IS21 PF01695.17 OAG40370.1 - 0.025 14.3 0.0 12 5.6 0.0 2.7 2 0 0 2 2 2 0 IstB-like ATP binding protein Septin PF00735.18 OAG40370.1 - 0.027 13.8 0.0 3.9 6.7 0.0 2.7 2 0 0 2 2 2 0 Septin HEAT_2 PF13646.6 OAG40370.1 - 0.03 14.7 0.0 11 6.5 0.0 3.8 2 1 1 3 3 3 0 HEAT repeats Cytidylate_kin PF02224.18 OAG40370.1 - 0.034 13.9 0.0 5.7 6.6 0.0 2.6 2 0 0 2 2 2 0 Cytidylate kinase T2SSE PF00437.20 OAG40370.1 - 0.038 13.0 0.1 2.6 7.0 0.0 2.6 3 0 0 3 3 2 0 Type II/IV secretion system protein AAA_5 PF07728.14 OAG40370.1 - 0.048 13.7 0.0 20 5.2 0.0 3.3 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Ploopntkinase3 PF18751.1 OAG40370.1 - 0.068 13.1 0.0 11 5.9 0.0 2.5 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 Mg_chelatase PF01078.21 OAG40370.1 - 0.072 12.5 0.0 3.7 6.9 0.0 2.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 OAG40370.1 - 0.076 12.2 0.0 11 5.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 OAG40370.1 - 0.082 12.4 0.0 14 5.1 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region MukB PF04310.12 OAG40370.1 - 0.086 12.6 0.0 13 5.5 0.0 2.6 3 0 0 3 3 2 0 MukB N-terminal HEAT PF02985.22 OAG40370.1 - 0.087 13.1 0.3 29 5.3 0.0 3.7 4 0 0 4 4 2 0 HEAT repeat ATP-synt_ab PF00006.25 OAG40370.1 - 0.12 12.0 0.0 10 5.7 0.0 2.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_17 PF13207.6 OAG40370.1 - 3.4 8.1 5.5 41 4.6 0.0 4.0 4 0 0 4 4 3 0 AAA domain FMO-like PF00743.19 OAG40371.1 - 8.5e-13 47.6 2.2 1.5e-11 43.5 0.5 2.7 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OAG40371.1 - 1.3e-09 38.1 0.0 2.4e-08 34.1 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 OAG40371.1 - 3.8e-05 23.7 0.7 0.11 12.5 0.0 3.4 3 1 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 OAG40371.1 - 0.00012 21.5 0.0 0.032 13.5 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG40371.1 - 0.00013 21.2 0.1 0.00041 19.6 0.0 1.8 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 OAG40371.1 - 0.00015 21.4 0.2 1.4 8.4 0.0 3.1 3 0 0 3 3 3 2 FAD dependent oxidoreductase Thi4 PF01946.17 OAG40371.1 - 0.00023 20.5 0.0 0.15 11.3 0.0 2.4 2 0 0 2 2 2 2 Thi4 family Pyr_redox_3 PF13738.6 OAG40371.1 - 0.003 16.9 0.2 0.28 10.4 0.3 3.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OAG40371.1 - 0.15 11.1 2.4 9.2 5.2 0.0 3.4 4 0 0 4 4 4 0 Glucose inhibited division protein A Cu_amine_oxid PF01179.20 OAG40372.1 - 1.3e-118 396.5 0.0 1.7e-118 396.1 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain DUF1965 PF09248.10 OAG40372.1 - 8.6e-18 63.9 0.1 2.5e-17 62.4 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1965) Cu_amine_oxidN2 PF02727.16 OAG40372.1 - 2.8e-05 24.3 0.0 6.2e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Clr5 PF14420.6 OAG40374.1 - 1.1e-17 63.9 0.9 1.1e-17 63.9 0.9 2.1 2 0 0 2 2 2 1 Clr5 domain TPR_12 PF13424.6 OAG40374.1 - 0.0015 18.8 3.6 0.081 13.2 0.3 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 OAG40374.1 - 0.0065 16.4 3.2 0.077 13.1 0.3 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_MalT PF17874.1 OAG40374.1 - 0.01 15.2 0.7 0.023 14.1 0.7 1.5 1 1 0 1 1 1 0 MalT-like TPR region TPR_1 PF00515.28 OAG40374.1 - 1.1 9.2 3.1 4.5 7.3 0.1 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 OAG40374.1 - 1.2 10.1 6.2 7.1 7.7 0.7 3.5 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 OAG40374.1 - 4.3 7.3 5.3 9.1 6.3 0.7 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat CDC37_N PF03234.14 OAG40375.1 - 3.8e-46 157.2 4.1 3.8e-46 157.2 4.1 3.3 3 0 0 3 3 3 2 Cdc37 N terminal kinase binding CDC37_M PF08565.11 OAG40375.1 - 8.1e-45 151.6 0.5 2.8e-44 149.8 0.5 2.0 1 0 0 1 1 1 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.10 OAG40375.1 - 6.7e-35 119.2 1.6 6.7e-35 119.2 1.6 2.2 2 0 0 2 2 2 1 Cdc37 C terminal domain ABC_membrane PF00664.23 OAG40376.1 - 8.8e-48 163.3 11.3 1.2e-47 162.9 11.3 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 OAG40376.1 - 3.3e-36 124.8 0.0 8.1e-36 123.5 0.0 1.7 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 OAG40376.1 - 3.4e-06 26.7 0.0 0.00045 19.7 0.0 2.6 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 OAG40376.1 - 0.0072 16.6 0.1 0.083 13.2 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OAG40376.1 - 0.0074 16.7 0.1 0.031 14.7 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 OAG40376.1 - 0.011 15.4 0.0 0.029 14.1 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain IstB_IS21 PF01695.17 OAG40376.1 - 0.028 14.1 0.0 0.24 11.1 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA PF00004.29 OAG40376.1 - 0.038 14.4 0.0 0.21 12.0 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_ATPase PF09818.9 OAG40376.1 - 0.046 12.5 0.4 0.14 11.0 0.1 1.9 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_25 PF13481.6 OAG40376.1 - 0.13 11.9 0.0 1.5 8.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 OAG40376.1 - 0.65 10.5 0.0 0.65 10.5 0.0 2.5 4 0 0 4 4 4 0 AAA domain SbcCD_C PF13558.6 OAG40376.1 - 1.1 9.6 4.4 1.9 8.8 0.7 3.2 3 1 0 3 3 2 0 Putative exonuclease SbcCD, C subunit MBOAT PF03062.19 OAG40377.1 - 3.9e-17 62.6 17.8 5.9e-17 62.1 17.8 1.4 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 OAG40377.1 - 0.00013 22.2 3.5 0.00042 20.5 3.5 1.9 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family DUF1279 PF06916.13 OAG40377.1 - 0.081 13.5 0.3 2.3 8.8 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1279) RGP PF03214.13 OAG40377.1 - 0.11 11.6 0.1 0.17 11.0 0.1 1.2 1 0 0 1 1 1 0 Reversibly glycosylated polypeptide WD40 PF00400.32 OAG40378.1 - 6.8e-33 112.2 23.8 3e-07 31.0 0.0 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG40378.1 - 8.6e-13 48.4 0.0 0.097 13.0 0.0 5.1 3 1 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 OAG40378.1 - 0.028 12.9 0.1 0.071 11.6 0.0 1.6 2 0 0 2 2 2 0 Cytochrome D1 heme domain Sporozoite_P67 PF05642.11 OAG40378.1 - 0.068 11.3 3.8 0.18 9.8 3.8 1.5 1 1 0 1 1 1 0 Sporozoite P67 surface antigen SUIM_assoc PF16619.5 OAG40378.1 - 0.24 11.5 9.5 1.1 9.4 9.5 2.1 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 WD40_like PF17005.5 OAG40378.1 - 0.33 10.2 0.0 18 4.5 0.0 2.3 1 1 1 2 2 2 0 WD40-like domain WD40 PF00400.32 OAG40379.1 - 1.6e-37 126.8 9.8 5.8e-06 26.9 0.1 7.5 7 1 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG40379.1 - 4.1e-14 52.6 0.0 0.002 18.4 0.0 5.5 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OAG40379.1 - 8.1e-05 22.6 0.0 0.00052 20.0 0.0 2.2 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 OAG40379.1 - 0.00025 19.9 0.3 0.46 9.1 0.2 2.8 1 1 2 3 3 3 2 Nucleoporin Nup120/160 WD40_like PF17005.5 OAG40379.1 - 0.0012 18.2 0.0 0.0021 17.4 0.0 1.4 1 0 0 1 1 1 1 WD40-like domain Frtz PF11768.8 OAG40379.1 - 0.32 9.2 0.0 0.45 8.8 0.0 1.1 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz Tetraspanin PF00335.20 OAG40380.1 - 0.051 13.3 0.1 0.051 13.3 0.1 2.1 2 0 0 2 2 2 0 Tetraspanin family MSC PF09402.10 OAG40381.1 - 4.5e-104 348.5 1.8 1.3e-103 347.0 1.8 1.7 1 1 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.7 OAG40381.1 - 5.2e-12 45.3 1.8 6e-12 45.1 0.1 2.0 2 0 0 2 2 2 1 HeH/LEM domain Peptidase_M16_C PF05193.21 OAG40381.1 - 0.12 12.4 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Peptidase M16 inactive domain Thymopoietin PF08198.11 OAG40381.1 - 0.14 11.8 0.0 0.32 10.6 0.0 1.6 1 0 0 1 1 1 0 Thymopoietin protein Enterotoxin_HS1 PF08090.11 OAG40382.1 - 7.4 6.6 9.1 0.45 10.5 3.3 2.0 2 0 0 2 2 2 0 Heat stable E.coli enterotoxin 1 Ribosomal_L16 PF00252.18 OAG40383.1 - 1.6e-43 147.9 0.1 2.1e-43 147.5 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e HAMP_N3 PF18575.1 OAG40383.1 - 0.027 14.0 0.0 2.5 7.7 0.0 2.5 2 0 0 2 2 2 0 HAMP N-terminal domain 3 Ribosomal_L7Ae PF01248.26 OAG40384.1 - 2e-23 81.9 0.0 2.3e-23 81.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family TM_PBP2_N PF16296.5 OAG40385.1 - 0.27 11.4 0.9 5 7.3 0.0 2.6 2 0 0 2 2 2 0 N-terminal of TM subunit in PBP-dependent ABC transporters TSC22 PF01166.18 OAG40385.1 - 6.4 7.2 24.9 0.3 11.4 1.5 4.5 4 0 0 4 4 4 0 TSC-22/dip/bun family His_Phos_1 PF00300.22 OAG40386.1 - 1.2e-12 47.9 0.7 5.5e-08 32.7 0.2 2.3 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) Plasmod_Pvs28 PF06247.11 OAG40386.1 - 0.073 13.4 0.0 0.13 12.6 0.0 1.3 1 0 0 1 1 1 0 Pvs28 EGF domain Metallophos PF00149.28 OAG40387.1 - 4.8e-12 46.8 1.3 5.3e-12 46.7 0.2 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OAG40387.1 - 0.13 12.4 0.0 2.4 8.3 0.0 2.4 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain PCI PF01399.27 OAG40390.1 - 7.4e-10 39.3 4.5 2.1e-09 37.8 0.0 3.3 3 0 0 3 3 3 1 PCI domain G-gamma PF00631.22 OAG40391.1 - 0.0037 17.2 0.4 0.0075 16.2 0.4 1.4 1 0 0 1 1 1 1 GGL domain zf-tcix PF14952.6 OAG40391.1 - 0.11 12.2 0.8 0.16 11.6 0.1 1.7 2 0 0 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding Rdx PF10262.9 OAG40392.1 - 1.6e-28 98.7 1.1 2e-27 95.2 1.1 2.2 1 1 0 1 1 1 1 Rdx family DUF2457 PF10446.9 OAG40394.1 - 4.9e-138 461.2 21.8 4.9e-138 461.2 21.8 2.9 2 1 1 3 3 3 1 Protein of unknown function (DUF2457) Arf PF00025.21 OAG40395.1 - 9.3e-57 191.3 0.0 1.1e-56 191.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 OAG40395.1 - 3.5e-10 39.6 0.1 8.9e-06 25.1 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 OAG40395.1 - 7.5e-06 25.5 0.0 1.1e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 OAG40395.1 - 9.1e-06 25.9 0.0 0.00024 21.3 0.0 2.1 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 OAG40395.1 - 0.00079 19.5 0.0 0.004 17.2 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 OAG40395.1 - 0.00086 18.9 0.0 0.006 16.2 0.0 2.0 1 1 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 OAG40395.1 - 0.032 13.6 0.0 0.099 12.0 0.0 1.8 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region cobW PF02492.19 OAG40395.1 - 0.054 13.1 0.4 2.1 7.9 0.0 2.1 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain GTP_EFTU PF00009.27 OAG40395.1 - 0.13 11.8 0.0 6.1 6.3 0.0 2.1 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain ACT PF01842.25 OAG40395.1 - 0.17 11.6 0.0 0.38 10.6 0.0 1.6 1 0 0 1 1 1 0 ACT domain Metallophos PF00149.28 OAG40396.1 - 3.5e-40 138.7 0.1 4.6e-40 138.3 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 OAG40396.1 - 4e-23 81.6 1.5 6.4e-23 80.9 0.9 1.7 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain LRR_4 PF12799.7 OAG40397.1 - 6e-13 48.8 11.7 0.00037 20.8 0.7 5.2 2 1 4 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OAG40397.1 - 5e-09 35.8 23.2 3.3e-07 30.0 4.9 5.0 5 1 1 6 6 6 3 Leucine rich repeat LRR_9 PF14580.6 OAG40397.1 - 3.4e-05 23.4 3.4 0.066 12.7 0.5 2.7 1 1 1 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.6 OAG40397.1 - 0.0029 17.5 12.5 6.1 7.2 0.5 5.4 5 0 0 5 5 5 3 Leucine Rich repeat LRR_1 PF00560.33 OAG40397.1 - 0.014 15.9 10.9 8.9 7.3 0.9 5.9 6 1 1 7 7 7 0 Leucine Rich Repeat DUF3336 PF11815.8 OAG40398.1 - 4.9e-48 162.3 0.9 7.6e-48 161.7 0.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 OAG40398.1 - 1.7e-17 64.3 0.1 1.6e-16 61.1 0.1 2.3 1 1 0 1 1 1 1 Patatin-like phospholipase TssO PF17561.2 OAG40398.1 - 0.053 13.6 0.5 0.1 12.7 0.5 1.5 1 0 0 1 1 1 0 Type VI secretion system, TssO SAT PF16073.5 OAG40398.1 - 0.27 11.0 0.8 1.3 8.7 0.8 1.9 1 1 0 1 1 1 0 Starter unit:ACP transacylase in aflatoxin biosynthesis AAA PF00004.29 OAG40399.1 - 4.6e-50 169.5 0.0 2.4e-42 144.5 0.0 2.9 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OAG40399.1 - 1.1e-10 41.1 0.0 4.4e-10 39.2 0.0 2.1 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 OAG40399.1 - 4.2e-07 30.5 0.2 3.6e-05 24.2 0.0 3.6 2 1 0 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.17 OAG40399.1 - 8.4e-07 28.9 0.0 2.8e-06 27.2 0.0 1.8 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_2 PF07724.14 OAG40399.1 - 8.8e-06 25.9 0.0 2.3e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 OAG40399.1 - 0.00055 20.0 0.0 0.0018 18.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activ_2 PF14532.6 OAG40399.1 - 0.00078 19.6 0.0 1.8 8.7 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain RNA_helicase PF00910.22 OAG40399.1 - 0.0012 19.2 0.0 0.0048 17.3 0.0 2.1 1 0 0 1 1 1 1 RNA helicase AAA_25 PF13481.6 OAG40399.1 - 0.0025 17.4 0.0 0.007 16.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 OAG40399.1 - 0.003 17.9 0.2 0.067 13.5 0.2 2.9 1 1 0 1 1 1 1 AAA domain Bromodomain PF00439.25 OAG40399.1 - 0.003 17.6 0.0 0.0073 16.4 0.0 1.6 1 0 0 1 1 1 1 Bromodomain TIP49 PF06068.13 OAG40399.1 - 0.0068 15.6 0.0 0.011 14.9 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain ABC_tran PF00005.27 OAG40399.1 - 0.0071 16.9 0.0 0.031 14.8 0.0 2.1 1 0 0 1 1 1 1 ABC transporter Torsin PF06309.11 OAG40399.1 - 0.0079 16.3 0.0 1.3 9.1 0.0 2.4 2 0 0 2 2 2 1 Torsin AAA_14 PF13173.6 OAG40399.1 - 0.0089 16.1 0.0 0.024 14.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 OAG40399.1 - 0.01 15.5 0.0 1.3 8.7 0.0 2.8 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_33 PF13671.6 OAG40399.1 - 0.012 15.8 0.0 0.051 13.7 0.0 2.2 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 OAG40399.1 - 0.012 15.3 0.0 0.034 13.9 0.0 1.7 2 0 0 2 2 1 0 AAA domain Mg_chelatase PF01078.21 OAG40399.1 - 0.029 13.8 0.1 0.076 12.4 0.1 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 OAG40399.1 - 0.042 14.4 0.0 0.21 12.2 0.0 2.3 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 OAG40399.1 - 0.047 13.4 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain NACHT PF05729.12 OAG40399.1 - 0.053 13.4 0.0 0.15 11.9 0.0 1.8 1 0 0 1 1 1 0 NACHT domain Parvo_NS1 PF01057.17 OAG40399.1 - 0.089 11.9 0.0 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 PhoH PF02562.16 OAG40399.1 - 0.095 12.1 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_7 PF12775.7 OAG40399.1 - 0.098 12.2 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region TsaE PF02367.17 OAG40399.1 - 0.14 12.2 0.0 2.4 8.2 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_3 PF07726.11 OAG40399.1 - 0.16 11.9 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 OAG40399.1 - 0.52 10.1 0.0 0.52 10.1 0.0 4.9 4 1 0 4 4 3 0 AAA domain UAA PF08449.11 OAG40400.1 - 1.5e-78 264.1 0.9 1.9e-78 263.8 0.9 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 OAG40400.1 - 7.1e-06 26.2 21.2 0.0013 18.9 5.0 2.8 3 1 0 3 3 3 2 EamA-like transporter family TPT PF03151.16 OAG40400.1 - 0.0004 19.8 7.2 0.1 12.0 1.9 2.2 2 0 0 2 2 2 2 Triose-phosphate Transporter family SLC35F PF06027.12 OAG40400.1 - 0.32 10.4 4.8 1.3 8.5 0.1 2.3 2 0 0 2 2 2 0 Solute carrier family 35 Fungal_trans PF04082.18 OAG40401.1 - 4.3e-22 78.4 0.1 7.1e-22 77.7 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG40401.1 - 5e-07 29.7 11.9 1.3e-06 28.4 11.9 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Orthopox_A5L PF06193.11 OAG40401.1 - 0.13 11.7 4.2 0.33 10.3 4.2 1.6 1 0 0 1 1 1 0 Orthopoxvirus A5L protein-like Pox_A_type_inc PF04508.12 OAG40401.1 - 1.4 8.9 4.8 3.7 7.6 4.8 1.7 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat CPSase_L_D2 PF02786.17 OAG40402.1 - 1.6e-109 364.4 0.0 4.1e-84 281.3 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 OAG40402.1 - 4e-39 133.7 0.1 1.1e-38 132.3 0.1 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp PF02222.22 OAG40402.1 - 4.6e-19 68.6 0.0 2.2e-08 33.9 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.13 OAG40402.1 - 1.2e-17 64.1 0.3 3.6e-08 33.2 0.1 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 OAG40402.1 - 5.7e-12 45.5 0.0 3.4e-05 23.6 0.0 2.9 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_5 PF13549.6 OAG40402.1 - 8.3e-05 22.1 0.1 0.053 13.0 0.1 2.9 3 0 0 3 3 3 2 ATP-grasp domain GARS_A PF01071.19 OAG40402.1 - 0.00028 20.7 0.1 0.1 12.3 0.1 2.7 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain zf-C2H2_jaz PF12171.8 OAG40402.1 - 0.00061 20.0 1.4 0.00061 20.0 1.4 2.1 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding Epimerase PF01370.21 OAG40402.1 - 0.0023 17.5 0.0 0.013 14.9 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.10 OAG40402.1 - 0.039 13.9 0.0 0.28 11.1 0.0 2.3 2 0 0 2 2 2 0 KR domain zf-C2H2 PF00096.26 OAG40402.1 - 0.075 13.5 6.4 0.19 12.3 1.5 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-met PF12874.7 OAG40402.1 - 0.085 13.3 0.8 0.19 12.1 0.8 1.7 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 OAG40402.1 - 0.45 11.5 1.7 1.2 10.1 0.3 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger SH3_9 PF14604.6 OAG40403.1 - 5.3e-31 106.2 2.2 7.1e-15 54.6 0.1 2.6 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 OAG40403.1 - 1.1e-28 98.5 2.6 8.9e-14 50.8 0.2 2.5 2 0 0 2 2 2 2 SH3 domain Cofilin_ADF PF00241.20 OAG40403.1 - 4.4e-14 52.3 0.0 7.4e-14 51.6 0.0 1.3 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein SH3_2 PF07653.17 OAG40403.1 - 7.7e-14 51.1 0.0 5e-07 29.3 0.0 2.9 3 0 0 3 3 3 2 Variant SH3 domain SH3_10 PF17902.1 OAG40403.1 - 0.0082 16.2 0.0 0.02 14.9 0.0 1.6 1 0 0 1 1 1 1 SH3 domain CBFD_NFYB_HMF PF00808.23 OAG40405.1 - 2.8e-26 91.6 1.3 5.1e-26 90.7 1.3 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 OAG40405.1 - 6.6e-08 33.0 1.5 1.3e-07 32.1 1.5 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CCDC24 PF15669.5 OAG40405.1 - 0.00079 19.4 0.7 0.0012 18.8 0.7 1.3 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 24 family TFIID-18kDa PF02269.16 OAG40405.1 - 0.0012 18.9 0.0 0.0019 18.2 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.13 OAG40405.1 - 0.0016 18.4 0.0 0.0037 17.2 0.0 1.6 2 0 0 2 2 2 1 Bromodomain associated CENP-T_C PF15511.6 OAG40405.1 - 0.017 15.3 0.1 0.034 14.3 0.0 1.5 1 1 1 2 2 2 0 Centromere kinetochore component CENP-T histone fold TFIID_20kDa PF03847.13 OAG40405.1 - 0.091 13.3 0.1 0.18 12.3 0.1 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Aminotran_1_2 PF00155.21 OAG40406.1 - 1.2e-13 50.9 0.0 1.7e-13 50.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 OAG40406.1 - 9.6e-05 21.3 0.0 0.00032 19.6 0.0 1.7 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase DegT_DnrJ_EryC1 PF01041.17 OAG40406.1 - 0.0023 17.3 0.0 0.017 14.4 0.0 2.0 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyr_redox_2 PF07992.14 OAG40407.1 - 1.6e-16 60.4 0.0 3.3e-15 56.1 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 OAG40407.1 - 3.2e-14 52.3 0.0 2.5e-12 46.0 0.0 2.1 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OAG40407.1 - 1.6e-12 47.3 0.0 2.5e-09 36.8 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG40407.1 - 1.8e-12 47.0 0.1 4.1e-10 39.3 0.0 2.3 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 OAG40407.1 - 1.2e-10 41.4 0.0 6.3e-08 32.7 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 OAG40407.1 - 5.9e-06 26.4 0.5 0.063 13.3 0.1 4.2 3 1 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.24 OAG40407.1 - 1.4e-05 24.9 0.2 0.26 10.8 0.0 4.3 3 1 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 OAG40407.1 - 4.4e-05 24.0 0.1 0.62 10.7 0.0 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 OAG40407.1 - 0.00042 20.7 0.3 0.41 11.1 0.1 3.5 3 1 0 3 3 3 1 Putative NAD(P)-binding Thi4 PF01946.17 OAG40407.1 - 0.00044 19.6 0.1 0.0046 16.2 0.0 2.3 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.22 OAG40407.1 - 0.0024 17.0 0.0 0.42 9.6 0.0 3.1 3 1 1 4 4 4 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 OAG40407.1 - 0.0026 16.9 0.0 0.0048 16.0 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 OAG40407.1 - 0.0037 16.0 1.0 0.045 12.5 0.1 2.7 3 0 0 3 3 3 1 HI0933-like protein 2-Hacid_dh_C PF02826.19 OAG40407.1 - 0.0041 16.5 0.0 0.0088 15.4 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 OAG40407.1 - 0.0085 16.2 0.0 0.1 12.7 0.0 2.2 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase FAD_oxidored PF12831.7 OAG40407.1 - 0.036 13.4 0.0 0.069 12.5 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_2 PF03446.15 OAG40407.1 - 0.077 13.2 0.0 0.34 11.1 0.0 2.0 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.16 OAG40407.1 - 0.12 12.1 0.0 1.1 8.9 0.0 2.3 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA MFS_1 PF07690.16 OAG40408.1 - 4.1e-32 111.5 29.2 5.7e-32 111.0 29.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 OAG40408.1 - 1.6e-05 24.4 12.9 0.00023 20.6 13.7 2.0 1 1 1 2 2 2 2 Uncharacterised MFS-type transporter YbfB DUF2929 PF11151.8 OAG40408.1 - 0.41 11.0 0.0 0.41 11.0 0.0 3.6 5 0 0 5 5 5 0 Protein of unknown function (DUF2929) DUF2401 PF10287.9 OAG40409.1 - 1.4e-87 293.1 0.0 2.4e-87 292.3 0.0 1.4 1 0 0 1 1 1 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.9 OAG40409.1 - 1e-23 83.5 1.6 1.4e-23 83.1 0.1 2.0 2 0 0 2 2 2 1 Glycine-rich protein domain (DUF2403) Atg14 PF10186.9 OAG40410.1 - 2.4e-60 204.3 1.0 3.4e-60 203.8 1.0 1.2 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 PEP-utilisers_N PF05524.13 OAG40410.1 - 0.025 14.7 9.6 0.057 13.6 9.6 1.7 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal Exonuc_VII_L PF02601.15 OAG40410.1 - 0.1 12.2 11.5 0.17 11.4 11.5 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit UPF0242 PF06785.11 OAG40410.1 - 0.21 11.7 14.7 0.38 10.8 14.7 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Vfa1 PF08432.10 OAG40410.1 - 0.27 11.5 11.4 0.7 10.2 11.4 1.7 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 AAA_23 PF13476.6 OAG40410.1 - 0.32 11.5 8.7 0.56 10.7 8.7 1.5 1 0 0 1 1 1 0 AAA domain FapA PF03961.13 OAG40410.1 - 0.64 8.6 7.3 0.96 8.0 7.3 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Asp-B-Hydro_N PF05279.11 OAG40410.1 - 0.93 9.5 15.9 1.7 8.6 15.9 1.4 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region HAUS-augmin3 PF14932.6 OAG40410.1 - 1.5 8.3 18.0 2.4 7.6 18.0 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 V_ATPase_I PF01496.19 OAG40410.1 - 6 4.6 9.0 8.5 4.1 9.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMPIT PF07851.13 OAG40410.1 - 6.3 5.9 9.2 9.2 5.4 9.2 1.3 1 0 0 1 1 1 0 TMPIT-like protein DUF4407 PF14362.6 OAG40410.1 - 6.8 6.0 17.0 13 5.0 17.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PSCyt3 PF07627.11 OAG40410.1 - 7.8 6.9 6.4 1.3 9.3 0.2 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1588) zf-B_box PF00643.24 OAG40411.1 - 0.5 10.6 2.3 0.93 9.7 2.3 1.4 1 0 0 1 1 1 0 B-box zinc finger MIP PF00230.20 OAG40412.1 - 1.9e-29 103.0 5.4 2.7e-29 102.5 5.4 1.2 1 0 0 1 1 1 1 Major intrinsic protein RTC4 PF14474.6 OAG40413.1 - 1e-26 93.5 0.0 1.5e-26 92.9 0.0 1.3 1 0 0 1 1 1 1 RTC4-like domain LtrA PF06772.11 OAG40414.1 - 3.1e-44 151.6 17.5 4.2e-44 151.2 17.5 1.1 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) Fungal_trans PF04082.18 OAG40416.1 - 3.7e-18 65.5 0.1 7.3e-18 64.6 0.1 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain FAD_binding_3 PF01494.19 OAG40417.1 - 2.6e-23 82.8 0.0 3.5e-23 82.4 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAG40417.1 - 3.8e-10 39.9 0.6 8e-05 22.4 0.3 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase Trp_halogenase PF04820.14 OAG40417.1 - 0.0011 17.9 2.1 0.37 9.6 0.0 2.2 2 0 0 2 2 2 2 Tryptophan halogenase NAD_binding_8 PF13450.6 OAG40417.1 - 0.0025 18.0 0.4 0.0056 16.9 0.4 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAG40417.1 - 0.0049 16.1 0.7 0.016 14.4 0.3 1.8 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAG40417.1 - 0.0096 15.9 0.1 0.25 11.3 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding SE PF08491.10 OAG40417.1 - 0.058 12.4 0.1 0.5 9.4 0.1 2.0 1 1 0 1 1 1 0 Squalene epoxidase AbrB_C PF18277.1 OAG40417.1 - 0.11 12.1 0.0 0.25 11.0 0.0 1.6 1 0 0 1 1 1 0 AbrB C-terminal domain MCRA PF06100.11 OAG40417.1 - 0.24 10.1 0.2 0.35 9.6 0.2 1.2 1 0 0 1 1 1 0 MCRA family p450 PF00067.22 OAG40418.1 - 1.9e-47 162.1 0.0 2.5e-47 161.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.18 OAG40419.1 - 4.9e-26 91.3 0.0 7.9e-26 90.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG40419.1 - 4.2e-12 46.0 3.2 7.5e-12 45.2 3.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugarporin_N PF11471.8 OAG40419.1 - 0.14 12.2 0.0 0.37 10.8 0.0 1.7 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension DUF1841 PF08897.11 OAG40419.1 - 0.17 11.9 0.0 0.35 10.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1841) Tannase PF07519.11 OAG40420.1 - 3e-99 333.1 0.1 3.5e-99 332.8 0.1 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.21 OAG40420.1 - 4.4e-07 29.6 0.1 0.00011 21.7 0.1 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 OAG40420.1 - 1.3e-05 24.5 0.0 0.00012 21.5 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 HCBP_related PF06594.11 OAG40420.1 - 0.023 14.6 0.1 0.09 12.7 0.0 2.0 2 0 0 2 2 2 0 Haemolysin-type calcium binding protein related domain Abhydrolase_1 PF00561.20 OAG40420.1 - 0.032 13.9 0.1 0.18 11.4 0.1 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold AAA_12 PF13087.6 OAG40421.1 - 5.1e-39 134.0 0.0 1e-38 133.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 OAG40421.1 - 4.2e-26 92.3 0.1 1.1e-25 90.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 OAG40421.1 - 7.1e-09 36.2 0.0 8.5e-08 32.7 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 OAG40421.1 - 1.2e-05 25.2 0.4 0.0022 17.7 0.0 2.9 3 0 0 3 3 3 1 AAA domain DUF2075 PF09848.9 OAG40421.1 - 1.3e-05 24.6 0.8 0.076 12.2 0.0 3.0 3 0 0 3 3 3 2 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.18 OAG40421.1 - 3.1e-05 23.9 0.1 0.097 12.4 0.0 3.0 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase zf-CCCH PF00642.24 OAG40421.1 - 4.9e-05 23.1 2.6 0.0001 22.1 2.6 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 OAG40421.1 - 0.00028 20.8 5.1 0.00056 19.9 5.1 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 OAG40421.1 - 0.004 16.9 4.3 0.0078 16.0 4.3 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger UvrD_C_2 PF13538.6 OAG40421.1 - 0.087 12.7 0.0 0.22 11.4 0.0 1.7 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain ResIII PF04851.15 OAG40421.1 - 0.095 12.7 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit MFS_1 PF07690.16 OAG40422.1 - 2.2e-51 174.9 37.2 2.2e-51 174.9 37.2 1.6 1 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG40422.1 - 3.1e-12 46.1 12.6 3.1e-12 46.1 12.6 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 OAG40422.1 - 2.2e-07 29.7 4.5 2.2e-07 29.7 4.5 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 OAG40422.1 - 3.2e-07 30.0 8.9 3.2e-07 30.0 8.9 2.3 1 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB DUF3382 PF11862.8 OAG40422.1 - 0.048 13.9 2.2 0.12 12.7 0.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3382) ECH_1 PF00378.20 OAG40423.1 - 1.3e-35 122.9 0.0 1.7e-35 122.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAG40423.1 - 3.9e-24 85.8 0.0 4.9e-24 85.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase AAA_12 PF13087.6 OAG40425.1 - 1.6e-32 112.7 0.0 2.7e-32 112.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 OAG40425.1 - 7.7e-19 68.5 0.0 1.6e-18 67.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OAG40425.1 - 3.8e-05 24.1 0.0 0.00064 20.1 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 OAG40425.1 - 0.00027 20.7 0.0 0.048 13.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 OAG40425.1 - 0.0007 19.4 0.0 3.6 7.2 0.0 3.4 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.6 OAG40425.1 - 0.0025 17.6 0.7 0.033 14.0 0.0 2.8 3 0 0 3 3 3 1 UvrD-like helicase C-terminal domain AAA PF00004.29 OAG40425.1 - 0.038 14.4 0.5 0.18 12.2 0.1 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 OAG40425.1 - 0.077 12.2 0.2 2.5 7.2 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 OAG40425.1 - 0.096 12.1 0.0 0.46 9.9 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein PHD PF00628.29 OAG40426.1 - 7.8e-08 32.1 12.4 1.4e-07 31.3 12.4 1.4 1 0 0 1 1 1 1 PHD-finger zf-PHD-like PF15446.6 OAG40426.1 - 0.013 15.1 4.9 0.024 14.3 4.9 1.4 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain C1_1 PF00130.22 OAG40426.1 - 0.068 13.1 14.2 0.31 11.0 8.7 2.2 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.6 OAG40426.1 - 0.094 12.3 9.3 0.23 11.0 9.3 1.7 1 1 0 1 1 1 0 PHD-finger zf-RING_7 PF02591.15 OAG40426.1 - 0.66 10.2 4.5 19 5.5 0.0 3.4 2 1 1 3 3 3 0 C4-type zinc ribbon domain E1-E2_ATPase PF00122.20 OAG40427.1 - 2.8e-51 173.6 0.1 2.8e-51 173.6 0.1 2.9 3 0 0 3 3 3 1 E1-E2 ATPase HMA PF00403.26 OAG40427.1 - 1.1e-44 150.7 0.8 4.7e-13 49.4 0.0 5.5 5 1 0 5 5 5 4 Heavy-metal-associated domain Hydrolase PF00702.26 OAG40427.1 - 1.2e-36 127.0 0.0 2.4e-36 126.0 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 OAG40427.1 - 0.0096 15.7 0.1 0.066 12.9 0.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DAHP_snth_FXD PF18152.1 OAG40427.1 - 0.16 11.8 0.2 18 5.2 0.0 3.9 4 0 0 4 4 4 0 DAHP synthase ferredoxin-like domain AMP-binding PF00501.28 OAG40428.1 - 1.5e-40 139.1 0.0 2.2e-40 138.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG40428.1 - 0.0042 18.0 0.0 0.01 16.8 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 OAG40428.1 - 0.11 12.4 0.1 0.6 10.1 0.0 2.4 2 1 0 2 2 2 0 Acetyl-coenzyme A synthetase N-terminus Seipin PF06775.14 OAG40429.1 - 2.9e-58 197.2 3.9 3.7e-58 196.9 3.9 1.1 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) RSN1_7TM PF02714.15 OAG40430.1 - 8.2e-91 304.1 23.9 8.2e-91 304.1 23.9 2.2 3 0 0 3 3 3 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 OAG40430.1 - 6.2e-37 126.8 0.1 6.2e-37 126.8 0.1 3.1 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 OAG40430.1 - 6.4e-30 104.7 2.7 1.1e-29 104.0 2.7 1.4 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 OAG40430.1 - 4e-19 68.6 0.9 2.1e-18 66.3 0.2 2.2 2 0 0 2 2 2 1 Extracellular tail, of 10TM putative phosphate transporter Not1 PF04054.15 OAG40431.1 - 6.3e-101 337.9 0.2 5.5e-100 334.8 0.0 2.5 3 0 0 3 3 3 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 OAG40431.1 - 6.8e-92 306.9 2.9 2.1e-91 305.3 1.6 2.5 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain DUF3819 PF12842.7 OAG40431.1 - 2.3e-50 170.3 0.5 2.3e-50 170.3 0.5 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF3819) CNOT1_TTP_bind PF16417.5 OAG40431.1 - 1.4e-39 135.2 0.0 4.6e-39 133.6 0.0 1.8 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 TTP binding domain CNOT1_HEAT PF16418.5 OAG40431.1 - 2.2e-19 70.0 0.0 8e-19 68.2 0.0 2.1 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 HEAT repeat ScsC_N PF18312.1 OAG40431.1 - 0.13 12.1 1.2 0.46 10.3 1.2 2.1 1 0 0 1 1 1 0 Copper resistance protein ScsC N-terminal domain DASH_Duo1 PF08651.10 OAG40433.1 - 1.9e-30 104.4 3.8 3.2e-30 103.7 3.8 1.4 1 0 0 1 1 1 1 DASH complex subunit Duo1 DASH_Dad2 PF08654.10 OAG40433.1 - 0.072 13.5 10.6 0.22 12.0 10.6 1.8 1 1 0 1 1 1 0 DASH complex subunit Dad2 TRH PF05438.12 OAG40433.1 - 0.11 12.2 8.2 0.012 15.4 3.5 1.6 1 1 0 1 1 1 0 Thyrotropin-releasing hormone (TRH) IPK PF03770.16 OAG40433.1 - 0.37 10.6 3.5 0.51 10.2 3.5 1.1 1 0 0 1 1 1 0 Inositol polyphosphate kinase Prominin PF05478.11 OAG40433.1 - 0.42 8.5 2.2 0.52 8.2 2.2 1.1 1 0 0 1 1 1 0 Prominin ALMT PF11744.8 OAG40433.1 - 0.48 9.2 5.2 0.55 9.0 5.2 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF745 PF05335.13 OAG40433.1 - 0.96 9.1 20.9 2.8 7.6 20.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF745) RR_TM4-6 PF06459.12 OAG40433.1 - 2.8 7.7 11.2 4.1 7.1 11.2 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Goodbye PF17109.5 OAG40433.1 - 3.7 8.0 5.7 6.6 7.2 0.5 2.2 2 0 0 2 2 2 0 fungal STAND N-terminal Goodbye domain Rtf2 PF04641.12 OAG40433.1 - 9.9 5.4 11.1 0.84 8.9 3.0 2.1 2 0 0 2 2 2 0 Rtf2 RING-finger DUF2457 PF10446.9 OAG40434.1 - 0.93 8.6 7.0 1.1 8.4 7.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Pkinase PF00069.25 OAG40435.1 - 2.2e-05 24.0 0.0 3.6e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 OAG40435.1 - 0.0012 18.8 0.0 0.0023 17.9 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 OAG40435.1 - 0.01 15.4 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 0 RIO1 family PIP49_C PF12260.8 OAG40435.1 - 0.36 10.4 1.1 0.69 9.5 0.0 1.8 2 0 0 2 2 2 0 Protein-kinase domain of FAM69 Zn_clus PF00172.18 OAG40436.1 - 0.27 11.4 11.0 0.058 13.5 6.9 2.1 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain NmrA PF05368.13 OAG40437.1 - 2.1e-32 112.6 0.0 2.5e-32 112.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG40437.1 - 3.5e-15 56.4 0.2 4.3e-15 56.1 0.2 1.1 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAG40437.1 - 1e-06 28.4 0.0 1.4e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 OAG40437.1 - 0.00033 19.9 0.0 0.0011 18.1 0.0 1.9 2 0 0 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.19 OAG40437.1 - 0.0072 15.4 0.0 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 OAG40437.1 - 0.012 15.5 0.5 0.021 14.7 0.5 1.3 1 0 0 1 1 1 0 KR domain adh_short PF00106.25 OAG40437.1 - 0.024 14.1 0.3 0.037 13.5 0.3 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Polysacc_synt_2 PF02719.15 OAG40437.1 - 0.11 11.6 0.0 3.2 6.8 0.0 2.1 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein DapB_N PF01113.20 OAG40437.1 - 0.15 12.2 0.1 0.36 11.0 0.1 1.6 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus CMD PF02627.20 OAG40438.1 - 3.6e-07 30.2 0.5 3.5e-05 23.8 0.1 2.5 2 1 0 2 2 2 2 Carboxymuconolactone decarboxylase family Dioxygenase_C PF00775.21 OAG40439.1 - 1.7e-43 148.1 0.0 2.4e-43 147.7 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 OAG40439.1 - 2.9e-26 91.1 0.0 4.7e-26 90.4 0.0 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 OAG40439.1 - 0.003 17.8 1.0 0.073 13.4 0.0 2.7 3 0 0 3 3 3 1 Carboxypeptidase regulatory-like domain Lactonase PF10282.9 OAG40440.1 - 2.9e-17 63.0 0.0 4.8e-17 62.2 0.0 1.3 1 1 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Arylesterase PF01731.20 OAG40440.1 - 0.078 13.2 0.0 0.41 10.9 0.0 2.1 2 0 0 2 2 2 0 Arylesterase DUF4394 PF14339.6 OAG40440.1 - 0.098 12.0 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4394) DUF1244 PF06844.11 OAG40440.1 - 0.16 12.2 0.1 0.48 10.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1244) Abhydrolase_6 PF12697.7 OAG40441.1 - 1.7e-12 48.4 1.7 1.7e-12 48.4 1.7 1.7 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAG40441.1 - 5.2e-11 42.7 0.0 2.2e-09 37.3 0.0 2.8 3 0 0 3 3 3 1 alpha/beta hydrolase fold Esterase PF00756.20 OAG40441.1 - 0.00013 21.7 0.0 0.00076 19.2 0.0 2.0 2 0 0 2 2 2 1 Putative esterase Hydrolase_4 PF12146.8 OAG40441.1 - 0.00022 20.6 0.0 0.0019 17.5 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 BAAT_C PF08840.11 OAG40441.1 - 0.08 12.8 0.0 0.19 11.6 0.0 1.6 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.21 OAG40441.1 - 0.14 11.6 0.0 4.5 6.7 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 OAG40441.1 - 0.19 11.5 0.0 2.4 7.9 0.0 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Amdase PF17645.1 OAG40442.1 - 9.1e-18 64.7 0.2 9.8e-18 64.6 0.2 1.1 1 0 0 1 1 1 1 Arylmalonate decarboxylase Asp_Glu_race PF01177.22 OAG40442.1 - 0.00013 21.9 0.0 0.00016 21.6 0.0 1.1 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase FCH PF00611.23 OAG40443.1 - 1.4e-16 60.6 0.0 2.9e-16 59.5 0.0 1.6 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.28 OAG40443.1 - 8.6e-12 44.5 0.0 2.5e-11 43.0 0.0 1.9 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 OAG40443.1 - 2.2e-10 40.1 0.0 2.8e-09 36.5 0.0 2.3 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.6 OAG40443.1 - 2e-09 37.2 0.0 5.3e-09 35.8 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain Rapsyn_N PF10579.9 OAG40443.1 - 0.064 13.4 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 Rapsyn N-terminal myristoylation and linker region Zip PF02535.22 OAG40444.1 - 0.46 9.6 3.1 0.5 9.5 3.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Sulf_transp PF04143.14 OAG40445.1 - 4.1e-32 112.0 31.6 1.3e-31 110.4 31.6 1.7 1 1 0 1 1 1 1 Sulphur transport NTP_transf_9 PF04248.12 OAG40446.1 - 4.6e-32 109.8 0.6 5.8e-32 109.4 0.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF427) Lact_bio_phlase PF09508.10 OAG40446.1 - 0.043 12.3 0.0 0.052 12.0 0.0 1.1 1 0 0 1 1 1 0 Lacto-N-biose phosphorylase N-terminal TIM barrel domain Mannosidase_ig PF17786.1 OAG40447.1 - 2.2e-18 66.6 1.1 6.5e-18 65.1 1.1 1.9 1 0 0 1 1 1 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 OAG40447.1 - 1.2e-12 48.4 1.2 5.5e-12 46.3 0.0 2.3 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.18 OAG40447.1 - 0.054 13.4 0.0 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, sugar binding domain Fungal_trans PF04082.18 OAG40448.1 - 1.6e-19 70.0 2.2 2.5e-19 69.3 0.1 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF4460 PF14687.6 OAG40448.1 - 0.039 14.0 0.0 0.092 12.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4460) Ferric_reduct PF01794.19 OAG40449.1 - 3.8e-16 59.4 15.2 8.3e-16 58.2 15.2 1.6 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 OAG40449.1 - 7.5e-09 35.7 0.1 3.7e-08 33.4 0.1 2.1 2 1 0 2 2 2 1 FAD-binding domain Cu-oxidase_2 PF07731.14 OAG40450.1 - 1.5e-43 147.8 1.4 2.8e-37 127.5 0.1 2.7 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 OAG40450.1 - 7.3e-40 135.7 3.7 2.2e-37 127.7 0.1 3.5 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase PF00394.22 OAG40450.1 - 2.4e-36 125.3 0.2 4.1e-30 105.0 0.0 3.2 3 0 0 3 3 3 2 Multicopper oxidase Cupredoxin_1 PF13473.6 OAG40450.1 - 0.029 14.5 0.0 7.1 6.8 0.0 2.7 2 0 0 2 2 2 0 Cupredoxin-like domain CFEM PF05730.11 OAG40452.1 - 2.1e-11 43.7 6.9 2.1e-11 43.7 6.9 1.6 2 0 0 2 2 2 1 CFEM domain Hairy_orange PF07527.13 OAG40453.1 - 0.13 12.5 0.5 1.7 8.9 0.2 2.4 2 0 0 2 2 2 0 Hairy Orange ADH_N PF08240.12 OAG40455.1 - 3.1e-25 88.2 3.1 6.7e-25 87.1 3.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG40455.1 - 5.7e-19 68.4 0.7 1.1e-18 67.5 0.1 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAG40455.1 - 6.2e-07 30.5 0.0 1.1e-06 29.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Amidinotransf PF02274.17 OAG40455.1 - 0.035 13.2 0.0 0.056 12.5 0.0 1.2 1 0 0 1 1 1 0 Amidinotransferase BTB PF00651.31 OAG40457.1 - 3.9e-09 36.7 0.1 1e-07 32.2 0.0 2.8 2 1 1 3 3 3 1 BTB/POZ domain Skp1_POZ PF03931.15 OAG40457.1 - 0.031 14.4 0.0 0.14 12.4 0.0 2.0 2 0 0 2 2 2 0 Skp1 family, tetramerisation domain ApoLp-III PF07464.11 OAG40459.1 - 0.14 12.2 0.1 0.14 12.2 0.1 3.1 2 1 1 3 3 3 0 Apolipophorin-III precursor (apoLp-III) mono-CXXC PF15626.6 OAG40460.1 - 0.51 10.7 6.2 0.11 12.9 1.2 2.5 2 0 0 2 2 2 0 single CXXC unit TFIIB PF00382.19 OAG40462.1 - 2.2e-25 88.5 0.1 9.9e-18 64.0 0.0 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.13 OAG40462.1 - 1.4e-18 67.1 3.8 1.4e-18 67.1 3.8 5.5 5 2 0 5 5 5 1 Brf1-like TBP-binding domain Lyase_1 PF00206.20 OAG40463.1 - 1.6e-41 142.8 0.0 2.7e-41 142.0 0.0 1.4 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 OAG40463.1 - 1.1e-20 74.0 0.1 1.1e-19 70.7 0.0 2.4 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminus YkyA PF10368.9 OAG40463.1 - 0.16 11.6 0.0 0.34 10.6 0.0 1.5 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein adh_short PF00106.25 OAG40464.1 - 3.4e-29 101.7 0.0 4.6e-29 101.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG40464.1 - 9.8e-22 77.6 0.0 1.2e-21 77.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG40464.1 - 5.4e-07 29.7 0.1 6.7e-07 29.4 0.1 1.1 1 0 0 1 1 1 1 KR domain RTA1 PF04479.13 OAG40465.1 - 5.8e-70 235.1 7.7 8.6e-70 234.5 7.7 1.3 1 0 0 1 1 1 1 RTA1 like protein NDUF_B12 PF08122.12 OAG40465.1 - 1.3 9.1 0.0 1.3 9.1 0.0 3.2 4 1 1 5 5 5 0 NADH-ubiquinone oxidoreductase B12 subunit family Fungal_trans PF04082.18 OAG40466.1 - 1.8e-06 27.2 2.7 3.3e-06 26.3 2.7 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain APH PF01636.23 OAG40467.1 - 2.1e-10 40.9 0.0 3.1e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 OAG40467.1 - 0.0016 17.9 0.0 0.017 14.5 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Choline_kinase PF01633.20 OAG40467.1 - 0.041 13.5 0.0 0.071 12.7 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Methyltransf_PK PF05891.12 OAG40468.1 - 6.1e-56 189.4 0.0 1.1e-30 106.8 0.0 2.8 2 1 0 2 2 2 2 AdoMet dependent proline di-methyltransferase Methyltransf_23 PF13489.6 OAG40468.1 - 2.8e-06 27.3 0.0 4.2e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG40468.1 - 0.014 16.1 0.0 3.7 8.3 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.12 OAG40468.1 - 0.019 15.6 0.0 1.5 9.5 0.0 2.6 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.12 OAG40468.1 - 0.053 14.3 0.0 0.46 11.2 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain Surp PF01805.20 OAG40469.1 - 2.2e-12 46.8 0.0 4e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 Surp module Aim21 PF11489.8 OAG40470.1 - 1.2e-167 560.0 76.0 1.2e-167 560.0 76.0 2.7 2 1 0 2 2 2 1 Altered inheritance of mitochondria protein 21 NAD_binding_8 PF13450.6 OAG40471.1 - 1e-07 32.1 0.0 2.9e-07 30.6 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 OAG40471.1 - 1.4e-07 31.2 0.0 3.2e-07 30.0 0.0 1.6 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 OAG40471.1 - 0.0021 17.3 0.1 0.012 14.9 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 OAG40471.1 - 0.0041 16.4 0.1 0.0071 15.6 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 OAG40471.1 - 0.013 14.8 0.1 0.024 13.9 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 OAG40471.1 - 0.013 14.8 0.1 0.023 14.0 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 OAG40471.1 - 0.041 13.2 0.0 0.06 12.7 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase DAO PF01266.24 OAG40471.1 - 0.052 13.1 0.0 0.098 12.2 0.0 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 OAG40471.1 - 0.055 12.5 0.2 0.14 11.2 0.0 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein TrkA_N PF02254.18 OAG40471.1 - 0.076 13.3 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain HI0933_like PF03486.14 OAG40471.1 - 0.11 11.2 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_9 PF13454.6 OAG40471.1 - 0.13 12.2 0.1 1.2 9.1 0.0 2.5 3 0 0 3 3 3 0 FAD-NAD(P)-binding TPT PF03151.16 OAG40472.1 - 1.8e-23 83.3 21.2 2.3e-23 83.0 21.2 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 OAG40472.1 - 0.0002 20.7 23.2 0.00036 19.8 23.2 1.4 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 OAG40472.1 - 0.00047 20.3 36.9 0.0028 17.8 14.9 2.7 3 0 0 3 3 3 2 EamA-like transporter family DUF3425 PF11905.8 OAG40475.1 - 5.2e-11 42.6 1.2 2.1e-10 40.6 1.2 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) Abhydrolase_6 PF12697.7 OAG40476.1 - 2.7e-11 44.5 0.0 3.4e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG40476.1 - 0.027 13.7 0.0 0.034 13.4 0.0 1.3 1 1 0 1 1 1 0 Serine aminopeptidase, S33 Peptidase_S8 PF00082.22 OAG40477.1 - 5.1e-13 48.9 0.4 1.3e-12 47.6 0.4 1.5 1 1 0 1 1 1 1 Subtilase family Ank_4 PF13637.6 OAG40477.1 - 0.18 12.4 0.1 8.2 7.1 0.0 3.1 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 OAG40479.1 - 1e-77 256.7 0.0 5.2e-10 39.8 0.0 10.3 2 2 7 11 11 11 11 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAG40479.1 - 9.6e-55 182.3 3.0 6.1e-08 33.1 0.0 15.0 6 4 10 16 16 16 15 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG40479.1 - 4.6e-41 134.1 5.2 8.6e-07 28.8 0.0 17.3 19 0 0 19 19 19 8 Ankyrin repeat Ank PF00023.30 OAG40479.1 - 3.9e-40 134.6 12.6 4.1e-06 27.0 0.0 16.6 17 0 0 17 17 17 8 Ankyrin repeat Ank_5 PF13857.6 OAG40479.1 - 2.1e-36 123.5 7.0 2.2e-06 27.8 0.0 13.5 8 5 5 14 14 14 8 Ankyrin repeats (many copies) ZZ PF00569.17 OAG40479.1 - 0.32 10.8 7.1 0.95 9.3 7.1 1.7 1 0 0 1 1 1 0 Zinc finger, ZZ type Methyltransf_34 PF11312.8 OAG40481.1 - 3.2e-103 345.2 0.0 3.8e-103 344.9 0.0 1.0 1 0 0 1 1 1 1 Putative SAM-dependent methyltransferase Ribosomal_L22e PF01776.17 OAG40482.1 - 2.5e-46 156.5 0.2 4.7e-46 155.7 0.2 1.4 1 0 0 1 1 1 1 Ribosomal L22e protein family DSPn PF14671.6 OAG40482.1 - 1.2e-41 142.5 0.0 1.6e-39 135.6 0.0 2.4 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 OAG40482.1 - 9.1e-17 61.1 0.2 2.1e-16 59.9 0.0 1.7 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 OAG40482.1 - 2.3e-05 24.1 0.0 4.4e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 OAG40482.1 - 0.043 13.9 0.0 0.1 12.7 0.0 1.6 1 0 0 1 1 1 0 Inositol hexakisphosphate CFEM PF05730.11 OAG40484.1 - 0.026 14.6 4.7 0.047 13.8 4.7 1.4 1 0 0 1 1 1 0 CFEM domain Stevor PF17410.2 OAG40484.1 - 0.076 12.6 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame LapA_dom PF06305.11 OAG40484.1 - 0.39 10.6 1.5 0.74 9.7 1.5 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Podoplanin PF05808.11 OAG40484.1 - 1.8 8.7 12.7 0.11 12.6 6.3 2.0 2 0 0 2 2 2 0 Podoplanin zf-AN1 PF01428.16 OAG40486.1 - 1.5e-10 41.1 6.0 2e-10 40.6 6.0 1.2 1 0 0 1 1 1 1 AN1-like Zinc finger Rad60-SLD PF11976.8 OAG40486.1 - 7e-08 32.2 0.0 1e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 OAG40486.1 - 2.9e-06 26.9 0.0 4.6e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family Transp_Tc5_C PF04236.15 OAG40486.1 - 0.0081 16.5 0.6 0.014 15.8 0.6 1.3 1 0 0 1 1 1 1 Tc5 transposase C-terminal domain Tubulin PF00091.25 OAG40487.1 - 2e-69 233.7 0.0 3e-69 233.2 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 OAG40487.1 - 2.7e-45 153.6 0.4 7.3e-45 152.2 0.1 1.7 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 OAG40487.1 - 5e-07 30.1 0.0 1.2e-06 28.8 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 OAG40487.1 - 0.053 13.2 0.0 0.14 11.8 0.0 1.7 1 0 0 1 1 1 0 Tubulin domain Tubulin_2 PF13809.6 OAG40487.1 - 0.067 12.4 0.0 0.096 11.9 0.0 1.2 1 0 0 1 1 1 0 Tubulin like GDPD PF03009.17 OAG40488.1 - 1.2e-32 113.7 0.0 1.8e-32 113.1 0.0 1.3 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.6 OAG40488.1 - 0.0003 21.2 0.1 0.00078 19.8 0.1 1.8 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family ADH_N PF08240.12 OAG40489.1 - 2.7e-25 88.4 2.0 6.6e-25 87.1 2.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG40489.1 - 5.2e-20 71.8 0.3 1e-19 70.8 0.3 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Sacchrp_dh_NADP PF03435.18 OAG40489.1 - 2.4e-05 24.6 0.1 4.9e-05 23.6 0.1 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain AlaDh_PNT_C PF01262.21 OAG40489.1 - 0.00013 21.4 1.1 0.00022 20.6 1.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Glu_dehyd_C PF16912.5 OAG40489.1 - 0.00018 21.1 0.1 0.00082 18.9 0.1 1.9 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 OAG40489.1 - 0.0014 19.6 0.0 0.0033 18.5 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Pep_deformylase PF01327.21 OAG40489.1 - 0.053 13.1 0.0 0.086 12.4 0.0 1.3 1 0 0 1 1 1 0 Polypeptide deformylase TrkA_N PF02254.18 OAG40489.1 - 0.06 13.6 0.1 0.11 12.8 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain UDPG_MGDP_dh_N PF03721.14 OAG40489.1 - 0.06 12.9 0.1 0.1 12.2 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Gp_dh_N PF00044.24 OAG40489.1 - 0.11 12.9 1.8 1.5 9.2 0.4 2.8 2 1 1 3 3 3 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 OAG40489.1 - 0.18 11.2 0.1 0.27 10.6 0.1 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IGFBP PF00219.18 OAG40489.1 - 0.8 10.4 4.8 0.19 12.4 0.8 2.0 2 0 0 2 2 1 0 Insulin-like growth factor binding protein TPR_16 PF13432.6 OAG40490.1 - 9.8e-13 48.5 20.0 0.012 16.3 0.0 8.1 6 2 1 7 7 7 4 Tetratricopeptide repeat TPR_19 PF14559.6 OAG40490.1 - 2.1e-12 47.3 15.1 0.00076 19.9 0.0 6.7 6 1 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 OAG40490.1 - 1.7e-11 43.3 30.8 0.25 11.5 0.2 11.5 12 0 0 12 12 12 4 Tetratricopeptide repeat TPR_1 PF00515.28 OAG40490.1 - 1e-06 28.3 26.0 0.71 9.8 0.1 9.4 11 0 0 11 11 10 3 Tetratricopeptide repeat TPR_8 PF13181.6 OAG40490.1 - 2.5e-06 27.3 19.7 0.24 11.7 0.0 9.8 11 0 0 11 11 11 2 Tetratricopeptide repeat TPR_9 PF13371.6 OAG40490.1 - 2.2e-05 24.5 10.0 0.00098 19.2 0.8 5.6 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 OAG40490.1 - 0.0001 22.8 32.7 2.7 9.0 0.2 10.1 10 2 2 12 12 9 2 Tetratricopeptide repeat TPR_7 PF13176.6 OAG40490.1 - 0.00011 21.9 14.2 7.3 6.9 0.6 9.0 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_12 PF13424.6 OAG40490.1 - 0.00031 21.0 35.4 0.0044 17.3 1.0 7.8 8 1 1 9 9 8 3 Tetratricopeptide repeat ANAPC3 PF12895.7 OAG40490.1 - 0.00065 19.9 8.3 1.4 9.2 0.6 4.7 4 0 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 OAG40490.1 - 0.00068 19.8 2.1 26 5.5 0.0 7.6 9 0 0 9 9 8 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 OAG40490.1 - 0.013 15.5 2.9 2.8 8.1 0.1 4.3 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.6 OAG40490.1 - 0.032 14.9 23.9 1.7 9.5 0.7 8.6 10 0 0 10 10 9 0 Tetratricopeptide repeat TPR_11 PF13414.6 OAG40490.1 - 0.075 12.7 5.1 3.4 7.4 0.0 5.2 5 1 1 6 6 6 0 TPR repeat TPR_20 PF14561.6 OAG40490.1 - 0.1 13.0 14.2 8.1 6.9 0.7 5.3 3 1 2 5 5 5 0 Tetratricopeptide repeat ANAPC5 PF12862.7 OAG40490.1 - 1 9.4 6.8 0.13 12.4 0.3 3.0 4 1 0 4 4 4 0 Anaphase-promoting complex subunit 5 Mt_ATP-synt_B PF05405.14 OAG40491.1 - 1.6e-52 177.4 6.2 2e-52 177.1 6.2 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF1539 PF07560.11 OAG40491.1 - 0.14 12.3 1.7 0.15 12.1 0.6 1.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1539) Fib_alpha PF08702.10 OAG40491.1 - 1.7 8.8 7.0 3.1 8.0 3.7 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family CBF PF03914.17 OAG40492.1 - 3.3e-34 118.4 0.2 7.9e-34 117.1 0.0 1.6 1 1 1 2 2 2 1 CBF/Mak21 family ToxB_N PF18224.1 OAG40496.1 - 0.14 12.1 0.1 0.37 10.8 0.1 1.7 1 0 0 1 1 1 0 ToxB N-terminal domain Peptidase_S21 PF00716.17 OAG40496.1 - 1.7 8.3 9.2 2.6 7.7 9.2 1.3 1 0 0 1 1 1 0 Assemblin (Peptidase family S21) GTP_EFTU PF00009.27 OAG40497.1 - 3.1e-48 163.9 0.0 5.4e-48 163.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.10 OAG40497.1 - 1.1e-24 86.5 1.4 2.9e-24 85.2 1.4 1.7 1 0 0 1 1 1 1 HBS1 N-terminus GTP_EFTU_D3 PF03143.17 OAG40497.1 - 5.1e-10 39.7 0.3 1.5e-08 35.0 0.0 2.8 3 0 0 3 3 3 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 OAG40497.1 - 5.6e-09 36.3 0.0 2.5e-08 34.2 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 OAG40497.1 - 1.3e-07 31.7 0.2 5.7e-06 26.4 0.0 3.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase Roc PF08477.13 OAG40497.1 - 0.0099 16.1 0.2 2.2 8.5 0.0 3.0 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 OAG40497.1 - 0.012 15.1 0.4 1.3 8.5 0.0 2.9 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 OAG40497.1 - 0.05 13.1 0.2 1.3 8.6 0.1 2.9 2 1 0 2 2 2 0 Ferrous iron transport protein B PBP1_TM PF14812.6 OAG40497.1 - 2.3 8.7 7.8 0.83 10.1 4.5 2.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal F-actin_cap_A PF01267.17 OAG40499.1 - 2e-83 279.9 0.0 2.3e-83 279.7 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit GST_N_3 PF13417.6 OAG40500.1 - 7.4e-20 71.2 0.0 1.3e-19 70.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OAG40500.1 - 1e-19 70.6 0.0 1.6e-19 69.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 OAG40500.1 - 1.9e-10 40.9 0.0 3.7e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAG40500.1 - 6.7e-10 38.8 0.1 1.4e-09 37.8 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 OAG40500.1 - 0.00026 21.5 0.0 0.00043 20.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OAG40500.1 - 0.00033 20.8 0.0 0.00059 20.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OAG40500.1 - 0.0016 18.6 0.0 0.0031 17.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Phage_C PF12025.8 OAG40500.1 - 0.068 13.0 0.0 0.63 9.9 0.0 2.1 2 0 0 2 2 2 0 Phage protein C Sigma70_r4 PF04545.16 OAG40500.1 - 0.12 11.9 0.2 0.22 11.1 0.2 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 HSP70 PF00012.20 OAG40501.1 - 6.6e-264 876.6 11.9 7.5e-264 876.5 11.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 OAG40501.1 - 4.4e-18 65.2 3.0 3.7e-17 62.1 0.4 2.1 1 1 0 2 2 2 1 MreB/Mbl protein DDR PF08841.10 OAG40501.1 - 0.0047 16.0 0.6 0.032 13.2 0.4 2.1 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain Radial_spoke_3 PF06098.11 OAG40501.1 - 0.02 14.2 0.8 0.039 13.2 0.8 1.4 1 0 0 1 1 1 0 Radial spoke protein 3 RTX_C PF08339.10 OAG40501.1 - 0.023 14.8 0.3 6.7 6.7 0.0 2.6 2 0 0 2 2 2 0 RTX C-terminal domain Hydantoinase_A PF01968.18 OAG40501.1 - 0.36 10.1 4.8 0.41 9.9 0.1 2.9 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase FtsA PF14450.6 OAG40501.1 - 0.62 10.5 7.4 8.7 6.8 0.3 3.6 3 2 0 3 3 3 0 Cell division protein FtsA Putative_PNPOx PF01243.20 OAG40503.1 - 4.2e-09 36.5 0.0 5.4e-06 26.5 0.0 2.6 2 1 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase FAD_binding_6 PF00970.24 OAG40503.1 - 0.0051 17.1 0.0 0.19 12.1 0.0 2.9 2 1 0 2 2 2 1 Oxidoreductase FAD-binding domain Fungal_trans_2 PF11951.8 OAG40504.1 - 9.1e-10 37.9 0.1 2.4e-09 36.5 0.1 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG40504.1 - 2.1e-05 24.5 12.0 4.4e-05 23.5 12.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PSI_integrin PF17205.3 OAG40504.1 - 0.013 15.2 2.1 0.013 15.2 2.1 1.9 2 0 0 2 2 2 0 Integrin plexin domain Amidase PF01425.21 OAG40505.1 - 1.2e-87 294.7 0.0 3.9e-87 293.1 0.0 1.7 1 1 0 1 1 1 1 Amidase MFS_1 PF07690.16 OAG40506.1 - 1.8e-26 93.0 33.8 2.8e-26 92.3 27.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PTR2 PF00854.21 OAG40506.1 - 0.0018 17.2 1.4 0.0033 16.3 0.2 2.1 3 0 0 3 3 3 1 POT family YjcB PF15940.5 OAG40506.1 - 1.3 9.2 5.0 7.1 6.9 0.1 3.3 3 0 0 3 3 3 0 Family of unknown function Sua5_yciO_yrdC PF01300.18 OAG40507.1 - 1.2e-52 178.0 0.0 1.9e-52 177.3 0.0 1.3 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 OAG40507.1 - 3.5e-15 56.7 0.0 1.8e-14 54.4 0.0 2.1 1 1 0 1 1 1 1 Putative GTP-binding controlling metal-binding VHS PF00790.19 OAG40508.1 - 4.7e-40 136.7 3.9 2.6e-39 134.3 0.1 2.6 3 0 0 3 3 3 1 VHS domain FYVE PF01363.21 OAG40508.1 - 2.2e-16 59.7 2.1 3.8e-16 59.0 2.1 1.4 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.20 OAG40508.1 - 4.4e-08 32.5 12.1 0.00042 20.0 2.6 3.4 3 0 0 3 3 3 2 Ubiquitin interaction motif GAT PF03127.14 OAG40508.1 - 7.9e-06 26.1 0.3 3.7e-05 23.9 0.0 2.3 2 0 0 2 2 2 1 GAT domain FYVE_2 PF02318.16 OAG40508.1 - 0.053 13.7 0.6 0.12 12.6 0.6 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger Ribosomal_S30AE PF02482.19 OAG40508.1 - 0.057 14.2 0.2 1.7 9.5 0.4 2.5 2 0 0 2 2 2 0 Sigma 54 modulation protein / S30EA ribosomal protein C1_1 PF00130.22 OAG40508.1 - 0.065 13.1 2.6 0.13 12.2 2.6 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Npa1 PF11707.8 OAG40508.1 - 0.12 11.7 0.1 0.19 11.0 0.1 1.3 1 0 0 1 1 1 0 Ribosome 60S biogenesis N-terminal DZR PF12773.7 OAG40508.1 - 0.4 10.7 3.2 0.83 9.7 3.2 1.5 1 0 0 1 1 1 0 Double zinc ribbon UCH PF00443.29 OAG40509.1 - 3.1e-49 167.8 0.0 4.8e-49 167.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OAG40509.1 - 5.6e-17 62.3 0.3 3.9e-13 49.7 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.20 OAG40509.1 - 0.0013 19.3 0.0 0.0032 18.0 0.0 1.8 1 0 0 1 1 1 1 Rhodanese-like domain USP8_dimer PF08969.11 OAG40509.1 - 0.016 15.4 0.1 0.04 14.1 0.1 1.7 1 0 0 1 1 1 0 USP8 dimerisation domain FtsJ PF01728.19 OAG40510.1 - 1.6e-61 207.5 0.0 2e-61 207.2 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase NFACT-C PF11923.8 OAG40511.1 - 4.4e-34 116.6 0.1 4.4e-34 116.6 0.1 3.4 4 0 0 4 4 4 1 NFACT protein C-terminal domain FbpA PF05833.11 OAG40511.1 - 9e-34 117.0 3.9 9e-34 117.0 3.9 1.8 2 1 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) NFACT-R_1 PF05670.13 OAG40511.1 - 7e-32 110.3 0.0 4.7e-31 107.7 0.0 2.4 2 0 0 2 2 2 1 NFACT protein RNA binding domain Clat_adaptor_s PF01217.20 OAG40511.1 - 8.5e-11 42.0 0.7 3.2e-10 40.1 0.7 2.1 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Ank_2 PF12796.7 OAG40512.1 - 5.5e-31 107.0 0.4 4.3e-08 33.6 0.0 7.8 8 0 0 8 8 8 6 Ankyrin repeats (3 copies) Ank PF00023.30 OAG40512.1 - 3.4e-25 87.3 6.3 0.0014 19.0 0.1 9.1 8 0 0 8 8 8 5 Ankyrin repeat Ank_3 PF13606.6 OAG40512.1 - 7e-23 78.2 10.3 0.00096 19.4 0.1 11.2 12 0 0 12 12 12 5 Ankyrin repeat Ank_4 PF13637.6 OAG40512.1 - 2.2e-21 75.9 0.2 0.0021 18.6 0.0 8.7 7 1 1 8 8 8 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 OAG40512.1 - 5.3e-21 74.4 4.3 0.0049 17.1 0.0 9.3 9 1 1 10 10 10 5 Ankyrin repeats (many copies) BUD22 PF09073.10 OAG40512.1 - 0.00032 20.2 5.5 0.00032 20.2 5.5 2.7 3 0 0 3 3 3 1 BUD22 TORC_N PF12884.7 OAG40512.1 - 0.18 12.6 1.0 0.73 10.7 1.0 2.0 1 0 0 1 1 1 0 Transducer of regulated CREB activity, N terminus Formyl_trans_N PF00551.19 OAG40513.1 - 4.3e-38 130.9 0.2 5.2e-38 130.6 0.2 1.1 1 0 0 1 1 1 1 Formyl transferase ACT PF01842.25 OAG40513.1 - 2.4e-11 43.2 0.0 1.1e-10 41.1 0.0 2.1 2 0 0 2 2 2 1 ACT domain ACT_6 PF13740.6 OAG40513.1 - 2.3e-05 24.3 0.0 6.1e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 ACT domain Arginase PF00491.21 OAG40514.1 - 8.2e-85 284.7 0.0 1.1e-84 284.3 0.0 1.1 1 0 0 1 1 1 1 Arginase family SAGA-Tad1 PF12767.7 OAG40515.1 - 1.5e-54 185.3 0.0 2e-54 184.8 0.0 1.2 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit WD40 PF00400.32 OAG40516.1 - 5.8e-30 102.9 27.7 0.00032 21.4 0.0 11.3 11 0 0 11 11 11 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG40516.1 - 9.7e-15 54.7 1.2 0.02 15.2 0.1 6.6 3 3 2 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 OAG40516.1 - 0.00054 19.8 1.7 8.1 6.5 0.0 4.7 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat eIF2A PF08662.11 OAG40516.1 - 0.001 19.0 0.7 1.9 8.3 0.0 4.0 3 3 2 5 5 5 2 Eukaryotic translation initiation factor eIF2A DUF1513 PF07433.11 OAG40516.1 - 0.051 12.6 1.3 0.21 10.6 0.1 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1513) WD40_like PF17005.5 OAG40516.1 - 0.084 12.2 0.0 6.8 5.9 0.0 2.4 2 1 0 2 2 2 0 WD40-like domain Pectate_lyase22 PF14583.6 OAG40516.1 - 0.11 11.2 0.0 0.23 10.1 0.0 1.5 1 0 0 1 1 1 0 Oligogalacturonate lyase Frtz PF11768.8 OAG40516.1 - 0.17 10.2 0.0 0.78 8.0 0.0 1.9 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz Ge1_WD40 PF16529.5 OAG40516.1 - 0.27 10.1 5.4 2.9 6.8 0.1 4.1 4 1 2 6 6 6 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Ribosomal_S18 PF01084.20 OAG40517.1 - 2e-14 53.5 0.0 3.8e-14 52.6 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S18 PPR_2 PF13041.6 OAG40518.1 - 1.7e-07 31.3 0.0 1 9.6 0.0 5.5 6 0 0 6 6 6 2 PPR repeat family PPR PF01535.20 OAG40518.1 - 3.5e-05 23.8 0.0 1.4 9.3 0.0 5.4 5 0 0 5 5 5 1 PPR repeat Terminase_4 PF05119.12 OAG40518.1 - 0.2 12.1 0.4 2.4 8.7 0.1 2.9 2 1 0 2 2 2 0 Phage terminase, small subunit TPR_14 PF13428.6 OAG40518.1 - 0.35 11.8 8.3 50 5.1 0.2 5.0 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 OAG40518.1 - 0.62 10.6 6.2 9.9 6.8 0.1 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat adh_short_C2 PF13561.6 OAG40520.1 - 2.1e-43 148.6 0.1 2.8e-43 148.2 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG40520.1 - 1.8e-34 119.0 0.1 2e-34 118.7 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG40520.1 - 1.8e-10 41.0 0.3 2.4e-10 40.6 0.3 1.2 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 OAG40520.1 - 0.0048 16.4 0.0 0.0065 15.9 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Dak1_2 PF13684.6 OAG40520.1 - 0.0074 15.4 0.1 0.022 13.9 0.0 1.7 2 0 0 2 2 2 1 Dihydroxyacetone kinase family Epimerase PF01370.21 OAG40520.1 - 0.064 12.7 0.0 0.091 12.2 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Fungal_trans_2 PF11951.8 OAG40521.1 - 1.7e-09 37.0 0.1 2.5e-09 36.5 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Yippee-Mis18 PF03226.14 OAG40522.1 - 2.6e-23 82.2 0.4 3.9e-23 81.7 0.4 1.3 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.8 OAG40522.1 - 0.18 12.0 1.9 8.1 6.7 0.0 2.1 2 0 0 2 2 2 0 C-terminal domain of RIG-I zf-C2H2_6 PF13912.6 OAG40523.1 - 0.0033 17.4 0.1 0.0033 17.4 0.1 7.2 9 0 0 9 9 9 2 C2H2-type zinc finger zf-C2H2 PF00096.26 OAG40523.1 - 0.022 15.2 39.4 0.049 14.1 0.1 8.3 6 1 0 6 6 6 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAG40523.1 - 0.039 14.8 0.1 0.039 14.8 0.1 8.1 8 0 0 8 8 8 0 C2H2-type zinc finger DUF3211 PF11485.8 OAG40524.1 - 0.062 13.5 0.0 0.3 11.3 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3211) PRP1_N PF06424.12 OAG40525.1 - 7.7e-49 165.9 5.2 1.9e-48 164.6 5.2 1.7 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.6 OAG40525.1 - 1.1e-28 97.4 40.8 3.8e-06 27.3 0.5 14.4 6 5 10 16 16 15 9 Tetratricopeptide repeat TPR_19 PF14559.6 OAG40525.1 - 2.2e-24 85.7 13.4 2.4e-08 34.3 0.4 9.3 5 2 3 8 8 8 4 Tetratricopeptide repeat TPR_17 PF13431.6 OAG40525.1 - 8.4e-13 47.7 0.6 6.3 7.4 0.0 10.2 9 1 0 9 9 9 1 Tetratricopeptide repeat TPR_2 PF07719.17 OAG40525.1 - 4.3e-11 42.0 14.7 0.092 12.9 0.0 10.0 12 0 0 12 12 10 3 Tetratricopeptide repeat TPR_8 PF13181.6 OAG40525.1 - 1.5e-09 37.3 0.1 0.097 12.9 0.0 6.9 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_16 PF13432.6 OAG40525.1 - 3.1e-09 37.3 19.8 0.16 12.6 3.3 8.5 7 2 2 9 9 9 4 Tetratricopeptide repeat TPR_11 PF13414.6 OAG40525.1 - 7.7e-08 31.9 0.0 2 8.2 0.0 6.1 5 0 0 5 5 5 2 TPR repeat TPR_1 PF00515.28 OAG40525.1 - 7.7e-06 25.5 0.0 0.38 10.6 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 OAG40525.1 - 3.8e-05 23.8 12.9 0.98 9.6 0.0 6.9 5 2 0 6 6 6 2 Tetratricopeptide repeat NARP1 PF12569.8 OAG40525.1 - 0.00012 21.1 11.0 1.1 8.1 0.0 6.1 5 2 3 8 8 8 2 NMDA receptor-regulated protein 1 TPR_21 PF09976.9 OAG40525.1 - 0.00022 21.0 8.1 0.036 13.8 0.9 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat-like domain TPR_15 PF13429.6 OAG40525.1 - 0.00076 18.8 7.6 0.00076 18.8 7.6 6.1 4 2 2 6 6 6 3 Tetratricopeptide repeat ANAPC3 PF12895.7 OAG40525.1 - 0.0021 18.2 1.3 39 4.6 0.0 5.0 5 2 1 6 6 5 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 OAG40525.1 - 0.012 15.6 1.5 2 8.7 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 OAG40525.1 - 0.027 15.1 9.8 54 4.7 0.1 8.4 10 0 0 10 10 9 0 Tetratricopeptide repeat Suf PF05843.14 OAG40525.1 - 0.044 13.8 0.1 3.9 7.4 0.0 3.2 3 1 0 3 3 3 0 Suppressor of forked protein (Suf) DUF3808 PF10300.9 OAG40525.1 - 0.061 12.1 0.7 12 4.5 0.0 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF3808) BTAD PF03704.17 OAG40525.1 - 7.7 6.9 13.8 2.7 8.4 0.3 4.2 3 1 1 4 4 4 0 Bacterial transcriptional activator domain Fungal_trans PF04082.18 OAG40526.1 - 7.6e-16 57.9 0.6 1.1e-15 57.4 0.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 OAG40527.1 - 7.3e-43 146.8 43.7 7.3e-43 146.8 43.7 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Keratin_2_head PF16208.5 OAG40527.1 - 0.9 9.7 5.1 0.19 11.9 0.9 1.9 2 0 0 2 2 2 0 Keratin type II head RrnaAD PF00398.20 OAG40528.1 - 5.4e-63 212.5 0.0 7.2e-63 212.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 OAG40528.1 - 4.9e-06 27.2 0.0 9.8e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG40528.1 - 6.9e-05 23.4 0.0 0.00014 22.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 OAG40528.1 - 0.0012 18.7 0.0 0.0018 18.0 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 OAG40528.1 - 0.0019 18.1 0.0 0.0036 17.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG40528.1 - 0.0026 18.5 0.0 0.0061 17.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 OAG40528.1 - 0.0057 16.0 0.0 0.0088 15.4 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase R3H-assoc PF13902.6 OAG40528.1 - 0.024 15.0 0.9 0.049 14.0 0.9 1.5 1 0 0 1 1 1 0 R3H-associated N-terminal domain Methyltransf_2 PF00891.18 OAG40528.1 - 0.027 13.8 0.0 0.042 13.1 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain MTS PF05175.14 OAG40528.1 - 0.032 13.8 0.0 0.05 13.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.13 OAG40528.1 - 0.1 12.0 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) AAA_lid_4 PF17864.1 OAG40528.1 - 0.1 12.3 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 RuvB AAA lid domain tRNA-synt_1d PF00750.19 OAG40530.1 - 3.5e-93 312.3 10.4 3.7e-92 308.9 10.4 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 OAG40530.1 - 6.2e-32 110.3 0.3 1.6e-31 109.0 0.3 1.8 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 OAG40530.1 - 3.6e-07 30.7 1.7 6.1e-07 29.9 0.1 2.4 2 0 0 2 2 2 1 Arginyl tRNA synthetase N terminal domain tRNA-synt_1e PF01406.19 OAG40530.1 - 0.039 13.3 0.0 0.097 12.0 0.0 1.6 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain Seryl_tRNA_N PF02403.22 OAG40530.1 - 0.062 13.5 1.6 0.21 11.8 1.6 1.9 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF3456 PF11938.8 OAG40530.1 - 1.3 9.6 3.9 0.48 10.9 0.7 1.9 2 0 0 2 2 2 0 TLR4 regulator and MIR-interacting MSAP DUF2256 PF10013.9 OAG40531.1 - 8 6.7 10.3 1.4 9.1 1.3 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) DUF3605 PF12239.8 OAG40532.1 - 3.7e-58 196.2 0.1 4.3e-58 196.0 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) FAD_binding_6 PF00970.24 OAG40533.1 - 1.4e-30 105.6 0.0 2.1e-30 105.0 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 OAG40533.1 - 6.5e-28 97.5 0.0 9.8e-28 97.0 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 OAG40533.1 - 8.6e-05 22.7 0.0 0.0051 16.9 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 OAG40533.1 - 0.024 14.8 0.0 0.042 14.1 0.0 1.4 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain Glyco_hydro_cc PF11790.8 OAG40534.1 - 4e-59 200.1 0.0 5.7e-59 199.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core TRP PF06011.12 OAG40535.1 - 3.8e-142 474.0 18.9 4.7e-142 473.7 18.9 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 OAG40535.1 - 5.5e-38 130.5 2.4 8.8e-38 129.8 2.4 1.3 1 0 0 1 1 1 1 ML-like domain E1_DerP2_DerF2 PF02221.15 OAG40535.1 - 2.9e-06 27.7 0.5 5.5e-06 26.8 0.5 1.4 1 0 0 1 1 1 1 ML domain DUF1153 PF06627.11 OAG40535.1 - 0.036 14.2 0.1 9.4 6.5 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1153) ETRAMP PF09716.10 OAG40535.1 - 0.57 10.3 0.0 0.57 10.3 0.0 3.4 4 1 0 5 5 5 0 Malarial early transcribed membrane protein (ETRAMP) RRM_1 PF00076.22 OAG40536.1 - 5.2e-35 119.1 0.1 1.2e-16 60.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OAG40536.1 - 2e-11 43.8 0.2 0.00015 21.8 0.0 2.8 2 1 0 2 2 2 2 RNA recognition motif RRM_3 PF08777.11 OAG40536.1 - 0.062 13.4 0.0 2.2 8.3 0.0 2.5 2 0 0 2 2 2 0 RNA binding motif TFIIA PF03153.13 OAG40536.1 - 1.6 8.6 19.5 2.2 8.2 19.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RabGAP-TBC PF00566.18 OAG40538.1 - 1e-48 165.9 0.0 3.2e-47 161.0 0.0 2.2 2 0 0 2 2 2 2 Rab-GTPase-TBC domain DWNN PF08783.11 OAG40539.1 - 3.8e-29 100.8 0.1 9.7e-29 99.5 0.1 1.7 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.6 OAG40539.1 - 8.9e-08 31.8 8.0 8.9e-08 31.8 8.0 1.9 2 0 0 2 2 1 1 Zinc knuckle U-box PF04564.15 OAG40539.1 - 2e-06 27.9 0.1 1.1e-05 25.5 0.0 2.3 2 0 0 2 2 2 1 U-box domain zf-CCHC PF00098.23 OAG40539.1 - 0.00043 20.2 1.6 0.00084 19.3 1.6 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 OAG40539.1 - 0.012 15.6 0.5 0.034 14.1 0.5 1.7 1 0 0 1 1 1 0 Zinc knuckle zf-RING_UBOX PF13445.6 OAG40539.1 - 0.041 13.9 6.2 0.089 12.8 6.2 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-CCHC_5 PF14787.6 OAG40539.1 - 0.08 12.7 0.9 0.24 11.1 0.9 1.7 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-RING_4 PF14570.6 OAG40539.1 - 0.31 10.9 4.8 0.72 9.7 4.8 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 OAG40539.1 - 0.58 10.4 7.9 1.5 9.0 7.9 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 OAG40539.1 - 0.61 10.0 7.9 1.5 8.8 7.9 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OAG40539.1 - 1.2 9.1 14.8 0.035 13.9 8.2 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OAG40539.1 - 2.7 7.9 10.7 1.8 8.5 4.7 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FAD_binding_3 PF01494.19 OAG40540.1 - 0.00091 18.6 0.0 0.0014 18.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain FGGY_C PF02782.16 OAG40541.1 - 5.6e-75 251.4 0.8 1.4e-74 250.2 0.6 1.8 3 0 0 3 3 3 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 OAG40541.1 - 5.4e-68 229.2 0.0 7.2e-68 228.8 0.0 1.1 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain MIP PF00230.20 OAG40542.1 - 4.9e-56 190.0 5.2 5.7e-56 189.8 5.2 1.0 1 0 0 1 1 1 1 Major intrinsic protein DUF4730 PF15873.5 OAG40542.1 - 2.1 8.7 4.8 0.68 10.2 0.3 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4730) DAO PF01266.24 OAG40543.1 - 1.1e-49 170.0 0.0 1.5e-49 169.5 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 OAG40543.1 - 2.8e-45 153.3 0.0 6.2e-45 152.1 0.0 1.6 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 OAG40543.1 - 7.8e-09 35.1 2.5 8.6e-08 31.7 2.5 2.1 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 OAG40543.1 - 7.6e-05 22.2 0.0 0.00013 21.4 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG40543.1 - 0.0002 20.7 0.6 0.0007 18.9 0.6 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG40543.1 - 0.0028 17.8 0.3 0.02 15.1 0.2 2.5 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 OAG40543.1 - 0.01 15.0 0.1 0.099 11.7 0.1 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 OAG40543.1 - 0.015 14.5 0.0 0.069 12.4 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 OAG40543.1 - 0.023 14.6 0.1 0.044 13.7 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.14 OAG40543.1 - 0.027 13.2 0.2 0.045 12.5 0.2 1.3 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.27 OAG40543.1 - 0.051 14.1 0.2 0.16 12.6 0.2 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 OAG40543.1 - 0.12 11.5 0.0 0.74 9.0 0.0 1.9 2 0 0 2 2 2 0 FAD binding domain HTH_57 PF18679.1 OAG40543.1 - 0.15 12.4 0.0 0.35 11.2 0.0 1.5 1 0 0 1 1 1 0 ThcOx helix turn helix domain MFS_1 PF07690.16 OAG40544.1 - 9.7e-22 77.4 17.0 9.7e-22 77.4 17.0 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 OAG40544.1 - 4.5e-05 22.1 1.7 4.5e-05 22.1 1.7 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) COesterase PF00135.28 OAG40545.1 - 4.2e-63 214.0 0.0 5.3e-63 213.6 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAG40545.1 - 5e-09 36.3 2.0 8.4e-08 32.3 2.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG40545.1 - 0.00017 22.3 2.3 0.00039 21.1 2.1 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 OAG40545.1 - 0.0064 16.0 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Arylesterase PF01731.20 OAG40547.1 - 3.8e-08 33.4 0.0 8.4e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 Arylesterase NHL PF01436.21 OAG40547.1 - 0.006 16.6 0.2 0.027 14.5 0.1 2.3 2 0 0 2 2 2 1 NHL repeat Fungal_trans PF04082.18 OAG40548.1 - 3e-22 78.9 0.1 4.6e-22 78.3 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG40548.1 - 2.5e-05 24.3 5.5 2.5e-05 24.3 5.5 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PSI PF01437.25 OAG40548.1 - 0.025 15.1 0.5 0.061 13.9 0.5 1.6 1 0 0 1 1 1 0 Plexin repeat CLZ PF16526.5 OAG40548.1 - 0.16 12.4 0.0 0.34 11.3 0.0 1.5 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Ribonuc_L-PSP PF01042.21 OAG40549.1 - 2.3e-19 69.6 0.0 2.6e-19 69.4 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP SHNi-TPR PF10516.9 OAG40550.1 - 2.3e-13 49.4 0.3 2.3e-13 49.4 0.3 2.2 2 0 0 2 2 2 1 SHNi-TPR TPR_16 PF13432.6 OAG40550.1 - 0.069 13.8 2.4 0.11 13.1 1.1 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 OAG40550.1 - 1.4 9.2 16.0 0.95 9.8 2.7 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 OAG40550.1 - 3.8 7.5 6.2 40 4.3 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat NOA36 PF06524.12 OAG40550.1 - 7.3 5.8 7.2 12 5.1 7.2 1.4 1 0 0 1 1 1 0 NOA36 protein DNA_pol_E_B PF04042.16 OAG40551.1 - 2.4e-48 164.3 0.0 3.3e-48 163.8 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B YadA_anchor PF03895.15 OAG40551.1 - 0.028 14.5 0.2 0.11 12.6 0.2 2.1 1 0 0 1 1 1 0 YadA-like membrane anchor domain Helo_like_N PF17111.5 OAG40552.1 - 0.002 17.6 1.4 0.002 17.6 1.4 1.6 2 0 0 2 2 2 1 Fungal N-terminal domain of STAND proteins Phage_holin_6_1 PF09682.10 OAG40552.1 - 0.22 12.0 2.2 0.42 11.0 2.2 1.4 1 0 0 1 1 1 0 Bacteriophage holin of superfamily 6 (Holin_LLH) Ribosomal_60s PF00428.19 OAG40552.1 - 0.36 11.5 7.6 1.4 9.5 1.6 2.9 2 0 0 2 2 2 0 60s Acidic ribosomal protein Lipoprotein_20 PF13942.6 OAG40553.1 - 0.34 10.8 4.8 0.67 9.8 4.8 1.4 1 0 0 1 1 1 0 YfhG lipoprotein V_ATPase_I PF01496.19 OAG40553.1 - 0.46 8.3 2.3 0.64 7.9 2.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Nup54 PF13874.6 OAG40553.1 - 0.54 10.4 8.4 0.41 10.8 5.8 2.2 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 SlyX PF04102.12 OAG40553.1 - 0.98 10.1 7.6 4.4 8.0 3.8 3.0 2 0 0 2 2 2 0 SlyX ATG16 PF08614.11 OAG40553.1 - 5.4 7.2 12.8 0.26 11.5 5.4 2.2 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) kleA_kleC PF17383.2 OAG40553.1 - 8.9 6.7 7.2 18 5.8 1.0 2.7 1 1 0 2 2 2 0 Uncharacterized KorC regulated protein A RRM_1 PF00076.22 OAG40554.1 - 1.3e-15 56.9 0.0 2e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SNO PF01174.19 OAG40555.1 - 5.3e-54 182.9 0.0 1.7e-43 148.7 0.0 2.1 2 0 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.14 OAG40555.1 - 2.9e-09 36.8 0.0 4.8e-08 32.8 0.0 2.1 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.28 OAG40555.1 - 0.00022 21.1 0.1 0.00044 20.1 0.1 1.5 1 1 0 1 1 1 1 Glutamine amidotransferase class-I DJ-1_PfpI PF01965.24 OAG40555.1 - 0.0033 17.2 0.0 0.011 15.5 0.0 1.7 2 0 0 2 2 2 1 DJ-1/PfpI family Peptidase_S51 PF03575.17 OAG40555.1 - 0.031 13.9 0.0 0.065 12.9 0.0 1.4 1 0 0 1 1 1 0 Peptidase family S51 ACPS PF01648.20 OAG40556.1 - 1.6e-10 41.1 0.0 5.3e-10 39.4 0.0 1.9 1 1 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily HK PF02110.15 OAG40557.1 - 3.9e-77 259.0 0.2 7.5e-77 258.0 0.2 1.4 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.17 OAG40557.1 - 2.8e-56 189.7 2.9 2.8e-56 189.7 2.9 1.6 2 0 0 2 2 2 1 Thiamine monophosphate synthase Phos_pyr_kin PF08543.12 OAG40557.1 - 0.00032 20.2 0.0 0.00091 18.7 0.0 1.7 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Carb_kinase PF01256.17 OAG40557.1 - 0.0031 17.0 0.1 0.0059 16.1 0.1 1.4 1 0 0 1 1 1 1 Carbohydrate kinase eIF-5_eIF-2B PF01873.17 OAG40558.1 - 1.9e-38 131.0 0.0 3.5e-38 130.1 0.0 1.5 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.18 OAG40558.1 - 1.9e-20 72.8 0.1 1.9e-20 72.8 0.1 2.2 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Lipase_GDSL_2 PF13472.6 OAG40559.1 - 9e-25 88.1 0.0 1.9e-24 87.0 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 OAG40559.1 - 5.1e-17 62.5 0.0 3.5e-16 59.8 0.0 1.9 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Voltage_CLC PF00654.20 OAG40560.1 - 2.3e-89 300.1 24.4 2.3e-89 300.1 24.4 1.8 2 0 0 2 2 2 1 Voltage gated chloride channel Yip1 PF04893.17 OAG40561.1 - 0.016 14.9 1.5 0.024 14.3 1.5 1.2 1 0 0 1 1 1 0 Yip1 domain DPPIV_N PF00930.21 OAG40562.1 - 3.1e-101 338.7 0.0 4.5e-101 338.1 0.0 1.3 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 OAG40562.1 - 1.3e-55 188.2 2.4 2.6e-55 187.2 2.4 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 OAG40562.1 - 0.00022 20.9 4.2 0.015 14.9 1.8 2.4 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.7 OAG40562.1 - 0.00094 19.8 1.9 0.024 15.2 0.3 3.2 2 1 0 2 2 2 1 Alpha/beta hydrolase family DLH PF01738.18 OAG40562.1 - 0.0036 16.9 0.0 0.012 15.2 0.0 1.7 1 1 0 1 1 1 1 Dienelactone hydrolase family Esterase PF00756.20 OAG40562.1 - 0.012 15.3 0.1 0.034 13.8 0.1 1.7 1 1 0 1 1 1 0 Putative esterase Abhydrolase_1 PF00561.20 OAG40562.1 - 0.041 13.5 0.2 0.15 11.7 0.1 1.9 1 1 1 2 2 2 0 alpha/beta hydrolase fold Fungal_trans PF04082.18 OAG40565.1 - 5.4e-15 55.1 0.1 8.8e-15 54.5 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG40565.1 - 2e-09 37.4 9.7 3.8e-09 36.5 9.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BRI3BP PF14965.6 OAG40565.1 - 0.0056 16.2 0.8 0.22 11.0 0.1 2.8 3 0 0 3 3 3 1 Negative regulator of p53/TP53 Cut12 PF11500.8 OAG40565.1 - 0.22 11.5 0.1 0.44 10.5 0.1 1.4 1 0 0 1 1 1 0 Spindle pole body formation-associated protein Tektin PF03148.14 OAG40566.1 - 0.00037 19.4 2.3 0.00066 18.6 2.3 1.3 1 0 0 1 1 1 1 Tektin family DUF3584 PF12128.8 OAG40566.1 - 0.00057 17.6 2.9 0.00094 16.8 2.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Fib_alpha PF08702.10 OAG40566.1 - 0.0062 16.7 1.9 0.034 14.3 1.0 2.4 1 1 1 2 2 2 1 Fibrinogen alpha/beta chain family Spc7 PF08317.11 OAG40566.1 - 0.021 13.8 1.5 0.045 12.6 1.5 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein Spore_III_AB PF09548.10 OAG40566.1 - 0.06 13.4 1.8 0.094 12.8 0.3 2.1 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) CorA PF01544.18 OAG40566.1 - 0.083 12.2 1.4 0.096 12.0 0.2 1.7 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein DUF1515 PF07439.11 OAG40566.1 - 0.098 12.7 0.9 0.3 11.1 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) NBP1 PF08537.10 OAG40566.1 - 0.11 11.9 4.3 0.32 10.4 4.3 1.7 1 1 0 1 1 1 0 Fungal Nap binding protein NBP1 ADIP PF11559.8 OAG40566.1 - 0.29 11.2 8.7 0.63 10.1 6.6 2.4 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Phage_int_SAM_1 PF02899.17 OAG40566.1 - 1.2 9.5 4.4 10 6.5 0.1 3.6 3 1 1 4 4 4 0 Phage integrase, N-terminal SAM-like domain adh_short_C2 PF13561.6 OAG40567.1 - 3.3e-56 190.4 0.0 4.1e-56 190.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG40567.1 - 6e-44 149.8 0.0 7.8e-44 149.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG40567.1 - 6.8e-12 45.7 0.0 9.4e-12 45.2 0.0 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 OAG40567.1 - 0.0048 16.3 0.0 0.0067 15.8 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) DUF5589 PF17672.1 OAG40567.1 - 0.024 14.6 0.0 0.037 14.0 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5589) MFS_1 PF07690.16 OAG40568.1 - 5.4e-40 137.4 59.3 8.6e-40 136.7 55.2 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 OAG40568.1 - 2.6e-09 36.1 21.6 3.9e-09 35.5 21.6 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) adh_short PF00106.25 OAG40569.1 - 6.5e-43 146.5 0.8 1.2e-42 145.6 0.8 1.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG40569.1 - 1.6e-38 132.6 0.4 6.6e-38 130.6 0.4 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG40569.1 - 4.1e-10 39.9 2.0 2.4e-09 37.4 0.1 2.1 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 OAG40569.1 - 0.00073 18.7 0.1 0.0014 17.8 0.1 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.20 OAG40569.1 - 0.0036 17.4 0.0 0.0069 16.5 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ADH_zinc_N PF00107.26 OAG40569.1 - 0.0056 16.7 0.1 0.02 14.8 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase F420_oxidored PF03807.17 OAG40569.1 - 0.014 15.9 0.1 0.035 14.7 0.1 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Glu_dehyd_C PF16912.5 OAG40569.1 - 0.022 14.2 0.2 0.045 13.2 0.0 1.6 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus Epimerase PF01370.21 OAG40569.1 - 0.032 13.7 0.2 0.072 12.5 0.2 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family tRNA_m1G_MT PF01746.21 OAG40569.1 - 0.078 12.7 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 tRNA (Guanine-1)-methyltransferase 3HCDH_N PF02737.18 OAG40569.1 - 0.095 12.6 0.2 0.29 11.0 0.1 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 OAG40569.1 - 0.12 11.8 0.3 0.22 10.9 0.0 1.5 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Sacchrp_dh_NADP PF03435.18 OAG40569.1 - 0.13 12.5 0.6 0.53 10.5 0.1 2.2 2 1 1 3 3 3 0 Saccharopine dehydrogenase NADP binding domain Baculo_p47 PF05112.12 OAG40569.1 - 0.15 11.6 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 Baculovirus P47 protein DUF1776 PF08643.10 OAG40569.1 - 0.15 11.4 0.0 0.29 10.5 0.0 1.4 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Sugar_tr PF00083.24 OAG40570.1 - 1.5e-71 241.6 23.9 1.8e-71 241.3 23.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG40570.1 - 6.4e-19 68.1 26.6 6.4e-19 68.1 26.6 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 OAG40570.1 - 0.00024 20.1 3.7 0.00024 20.1 3.7 1.6 2 0 0 2 2 2 1 MFS_1 like family Phage_holin_2_4 PF16082.5 OAG40570.1 - 0.087 12.6 4.5 0.061 13.1 1.0 2.4 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like Glyco_hydro_31 PF01055.26 OAG40571.1 - 3.7e-111 372.4 2.0 5e-111 372.0 2.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 OAG40571.1 - 4e-19 68.7 0.2 7.7e-18 64.6 0.2 2.9 3 0 0 3 3 3 1 Galactose mutarotase-like GST_N_3 PF13417.6 OAG40572.1 - 1.5e-11 44.6 0.0 3.2e-11 43.5 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OAG40572.1 - 1.3e-08 35.0 0.0 2.3e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAG40572.1 - 3.4e-08 33.4 0.3 7.5e-08 32.3 0.1 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 OAG40572.1 - 0.0047 17.2 0.0 0.029 14.7 0.0 2.1 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain adh_short_C2 PF13561.6 OAG40573.1 - 1.3e-61 208.1 0.9 1.5e-61 207.9 0.9 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG40573.1 - 1.1e-42 145.7 0.5 1.4e-42 145.4 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG40573.1 - 6.1e-15 55.6 0.7 1.2e-14 54.7 0.3 1.6 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 OAG40573.1 - 0.0025 17.3 0.1 0.054 12.9 0.0 2.3 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family S4 PF01479.25 OAG40573.1 - 0.024 14.3 0.0 0.076 12.7 0.0 1.9 1 0 0 1 1 1 0 S4 domain Ank_2 PF12796.7 OAG40574.1 - 4.2e-57 190.7 8.3 2.5e-10 40.8 0.0 8.4 2 1 6 9 9 9 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAG40574.1 - 1.1e-45 153.5 14.4 1.1e-07 32.2 0.0 11.7 4 2 10 14 14 14 13 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG40574.1 - 1.2e-44 145.1 5.5 0.003 17.9 0.0 14.0 14 0 0 14 14 14 10 Ankyrin repeat Ank_5 PF13857.6 OAG40574.1 - 1.4e-44 149.6 8.7 3e-06 27.4 0.0 9.3 8 1 1 9 9 9 7 Ankyrin repeats (many copies) Ank PF00023.30 OAG40574.1 - 8.6e-37 124.0 10.4 1.5e-05 25.2 0.0 13.0 13 0 0 13 13 13 8 Ankyrin repeat Tmemb_170 PF10190.9 OAG40575.1 - 2.1e-16 60.2 10.9 1.3e-14 54.5 4.3 2.1 2 0 0 2 2 2 2 Putative transmembrane protein 170 PRA1 PF03208.19 OAG40575.1 - 0.43 10.2 3.2 1.1 8.9 3.2 1.7 1 1 0 1 1 1 0 PRA1 family protein Tudor_3 PF18115.1 OAG40576.1 - 7.2e-07 29.0 0.0 1.3e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain TUDOR PF00567.24 OAG40576.1 - 0.00036 20.5 0.0 0.0071 16.4 0.0 2.2 2 0 0 2 2 2 1 Tudor domain LBR_tudor PF09465.10 OAG40576.1 - 0.023 14.5 0.1 0.068 13.0 0.0 1.8 2 0 0 2 2 2 0 Lamin-B receptor of TUDOR domain Fis1_TPR_C PF14853.6 OAG40576.1 - 0.027 14.6 0.7 0.048 13.7 0.7 1.3 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat DUF4537 PF15057.6 OAG40576.1 - 0.046 13.7 0.0 0.082 12.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4537) Tudor_2 PF18104.1 OAG40576.1 - 0.053 13.2 0.0 0.14 11.8 0.0 1.8 1 0 0 1 1 1 0 Jumonji domain-containing protein 2A Tudor domain DUF2730 PF10805.8 OAG40576.1 - 0.073 13.2 0.5 0.13 12.4 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) PAP1 PF08601.10 OAG40577.1 - 1.1e-99 334.7 21.7 1.1e-99 334.7 21.7 3.0 2 1 1 3 3 3 1 Transcription factor PAP1 bZIP_1 PF00170.21 OAG40577.1 - 1.7e-08 34.4 10.2 4e-08 33.2 10.2 1.6 1 0 0 1 1 1 1 bZIP transcription factor ERM PF00769.19 OAG40577.1 - 0.0009 19.1 2.8 0.002 18.0 2.8 1.6 1 0 0 1 1 1 1 Ezrin/radixin/moesin family SHE3 PF17078.5 OAG40577.1 - 0.0025 17.6 3.5 0.0056 16.4 3.5 1.5 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 IL11 PF07400.11 OAG40577.1 - 0.02 14.5 0.8 0.037 13.7 0.8 1.3 1 0 0 1 1 1 0 Interleukin 11 bZIP_Maf PF03131.17 OAG40577.1 - 0.068 13.7 8.4 0.17 12.4 8.4 1.7 1 0 0 1 1 1 0 bZIP Maf transcription factor bZIP_2 PF07716.15 OAG40577.1 - 0.11 12.6 14.1 0.28 11.3 12.6 2.2 1 1 1 2 2 2 0 Basic region leucine zipper SlyX PF04102.12 OAG40577.1 - 0.16 12.6 0.5 0.48 11.1 0.5 1.9 1 0 0 1 1 1 0 SlyX EMP24_GP25L PF01105.24 OAG40577.1 - 0.32 10.9 0.9 0.73 9.8 0.9 1.5 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD DUF2433 PF10360.9 OAG40578.1 - 3.6e-46 156.3 0.0 6e-46 155.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) Metallophos PF00149.28 OAG40578.1 - 0.00024 21.6 0.0 0.00057 20.4 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OAG40578.1 - 0.0043 17.3 0.0 0.018 15.3 0.0 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain NPC1_N PF16414.5 OAG40579.1 - 1.9e-84 283.1 8.8 2.6e-84 282.6 8.8 1.2 1 0 0 1 1 1 1 Niemann-Pick C1 N terminus Patched PF02460.18 OAG40579.1 - 4.3e-75 253.4 5.7 1.2e-47 162.6 0.0 2.3 2 0 0 2 2 2 2 Patched family Sterol-sensing PF12349.8 OAG40579.1 - 3.1e-51 173.2 6.4 3.1e-51 173.2 6.4 3.1 2 1 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.15 OAG40579.1 - 1.7e-07 30.5 27.0 4.5e-05 22.5 9.1 2.3 2 0 0 2 2 2 2 MMPL family Folate_rec PF03024.14 OAG40579.1 - 0.004 17.1 3.3 0.0081 16.0 3.3 1.4 1 0 0 1 1 1 1 Folate receptor family CaM_bdg_C0 PF10562.9 OAG40579.1 - 0.047 13.7 0.2 0.095 12.8 0.2 1.5 1 0 0 1 1 1 0 Calmodulin-binding domain C0 of NMDA receptor NR1 subunit ACR_tran PF00873.19 OAG40579.1 - 0.76 7.4 17.7 0.041 11.5 11.6 1.8 2 0 0 2 2 2 0 AcrB/AcrD/AcrF family zf-Nse PF11789.8 OAG40580.1 - 1.6e-18 66.3 0.3 3e-18 65.4 0.3 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 OAG40580.1 - 0.001 19.1 0.0 0.0027 17.7 0.0 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OAG40580.1 - 0.002 17.9 0.6 0.011 15.5 0.0 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) U-box PF04564.15 OAG40580.1 - 0.0097 16.1 0.1 0.84 9.9 0.1 2.9 1 1 0 1 1 1 1 U-box domain zf-MIZ PF02891.20 OAG40580.1 - 0.027 14.2 0.9 0.11 12.2 0.0 2.2 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger zf-C3HC4 PF00097.25 OAG40580.1 - 0.21 11.5 0.7 4.7 7.2 0.0 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) YjeJ PF15922.5 OAG40580.1 - 1.2 8.3 3.4 15 4.7 0.3 2.2 2 0 0 2 2 2 0 YjeJ-like FAD_binding_4 PF01565.23 OAG40581.1 - 1.2e-19 70.4 4.8 3.1e-19 69.1 4.2 2.0 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 OAG40581.1 - 8.4e-10 38.6 0.1 2.1e-09 37.3 0.1 1.7 1 0 0 1 1 1 1 Berberine and berberine like DUF4404 PF14357.6 OAG40582.1 - 1.3 9.7 5.0 14 6.4 3.0 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) AAA_22 PF13401.6 OAG40584.1 - 4.6e-05 23.7 0.0 0.14 12.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 OAG40584.1 - 0.002 18.6 0.1 2.4 8.5 0.1 2.4 2 0 0 2 2 2 2 AAA ATPase domain Zeta_toxin PF06414.12 OAG40584.1 - 0.0042 16.4 0.0 0.0076 15.5 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin DUF853 PF05872.12 OAG40584.1 - 0.005 15.5 0.1 0.013 14.2 0.1 1.6 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF853) AAA PF00004.29 OAG40584.1 - 0.071 13.5 0.2 0.42 11.1 0.1 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF4158 PF13700.6 OAG40584.1 - 0.094 12.5 0.4 0.22 11.3 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4158) AAA_10 PF12846.7 OAG40584.1 - 0.15 11.0 0.0 5.9 5.7 0.0 2.4 3 0 0 3 3 3 0 AAA-like domain Methyltransf_23 PF13489.6 OAG40585.1 - 5.5e-15 55.6 0.0 8.2e-15 55.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG40585.1 - 2.6e-09 37.6 0.0 4.2e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG40585.1 - 4.5e-07 30.5 0.0 8.9e-07 29.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG40585.1 - 1.9e-05 25.3 0.0 4.2e-05 24.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG40585.1 - 5.7e-05 22.9 0.0 0.0004 20.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAG40585.1 - 0.059 12.7 0.0 0.11 11.8 0.0 1.5 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family MTS PF05175.14 OAG40585.1 - 0.085 12.4 0.0 1.5 8.3 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase small domain NicO PF03824.16 OAG40586.1 - 2.7e-59 200.8 14.2 6.8e-57 193.0 6.0 2.3 2 0 0 2 2 2 2 High-affinity nickel-transport protein DHHC PF01529.20 OAG40586.1 - 1.7 8.8 5.9 19 5.3 0.2 3.3 3 0 0 3 3 3 0 DHHC palmitoyltransferase ODV-E18 PF10717.9 OAG40586.1 - 3.1 7.7 9.8 0.14 12.0 2.1 2.4 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 CTP_synth_N PF06418.14 OAG40587.1 - 8.8e-123 408.8 0.1 1.2e-122 408.4 0.1 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 OAG40587.1 - 2e-58 197.3 0.0 3.3e-58 196.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 OAG40587.1 - 6e-06 26.2 0.1 7.1e-05 22.7 0.1 2.4 1 1 0 1 1 1 1 Peptidase C26 GTP_EFTU PF00009.27 OAG40588.1 - 1.2e-48 165.2 0.0 1.7e-48 164.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFTUD2 PF16004.5 OAG40588.1 - 1e-37 129.4 9.4 1.9e-37 128.6 9.4 1.4 1 0 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_IV PF03764.18 OAG40588.1 - 4.8e-23 81.2 0.0 1.3e-22 79.8 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 OAG40588.1 - 2.4e-16 59.5 0.0 7.2e-16 58.0 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 OAG40588.1 - 5e-07 29.7 0.1 1.9e-06 27.9 0.0 2.0 2 0 0 2 2 2 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 OAG40588.1 - 5.4e-07 29.9 0.0 1.5e-06 28.5 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 OAG40588.1 - 0.00012 22.1 0.2 0.00024 21.2 0.2 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 OAG40588.1 - 0.0042 16.7 0.0 0.009 15.6 0.0 1.5 1 0 0 1 1 1 1 Ras family Septin PF00735.18 OAG40588.1 - 0.057 12.7 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Septin Roc PF08477.13 OAG40588.1 - 0.15 12.3 0.0 0.85 9.9 0.0 2.1 1 1 1 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Fungal_trans_2 PF11951.8 OAG40589.1 - 0.0033 16.3 1.1 0.012 14.4 0.5 2.0 1 1 1 2 2 2 1 Fungal specific transcription factor domain RTA1 PF04479.13 OAG40590.1 - 5.8e-64 215.5 8.0 8e-64 215.1 8.0 1.2 1 0 0 1 1 1 1 RTA1 like protein HSP70 PF00012.20 OAG40591.1 - 1.4e-227 756.7 9.6 1.5e-227 756.6 9.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 OAG40591.1 - 6.8e-16 58.0 0.1 1.2e-14 53.9 0.1 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 OAG40591.1 - 0.00021 21.1 0.0 0.00046 20.0 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.10 OAG40591.1 - 0.017 14.1 0.1 0.3 10.0 0.0 2.3 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain FtsA PF14450.6 OAG40591.1 - 0.1 13.0 3.5 7.6 7.0 0.1 3.4 2 1 0 2 2 2 0 Cell division protein FtsA ATP-synt_DE PF00401.20 OAG40591.1 - 0.12 12.7 5.2 0.35 11.2 1.0 2.9 2 0 0 2 2 2 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain RRF PF01765.19 OAG40592.1 - 5.2e-33 114.3 0.5 1e-32 113.4 0.5 1.5 1 0 0 1 1 1 1 Ribosome recycling factor DUF883 PF05957.13 OAG40592.1 - 8.4 7.1 7.7 31 5.3 0.9 3.2 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) TPT PF03151.16 OAG40593.1 - 2.4e-15 56.6 8.4 3.5e-07 29.9 0.2 3.4 3 1 0 3 3 3 3 Triose-phosphate Transporter family DUF2178 PF09946.9 OAG40593.1 - 0.048 13.8 2.1 0.1 12.8 0.5 2.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2178) DNA_pol_phi PF04931.13 OAG40594.1 - 0.091 10.9 0.1 0.16 10.0 0.1 1.3 1 0 0 1 1 1 0 DNA polymerase phi DUF3844 PF12955.7 OAG40595.1 - 5.7e-34 116.4 6.2 8.9e-34 115.8 6.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) Bromodomain PF00439.25 OAG40596.1 - 6.9e-38 128.6 6.1 5.7e-19 68.0 0.9 2.4 2 0 0 2 2 2 2 Bromodomain OmpH PF03938.14 OAG40596.1 - 0.03 14.7 3.2 7.1 7.0 0.0 3.0 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) DUF2536 PF10750.9 OAG40596.1 - 0.055 13.4 0.1 0.1 12.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2536) Exo5 PF09810.9 OAG40596.1 - 0.18 11.3 1.2 0.25 10.8 0.2 1.7 2 0 0 2 2 2 0 Exonuclease V - a 5' deoxyribonuclease Muted PF14942.6 OAG40596.1 - 1.4 9.3 6.3 2.9 8.2 0.2 2.6 3 0 0 3 3 3 0 Organelle biogenesis, Muted-like protein CKS PF01111.19 OAG40597.1 - 6.5e-31 106.4 0.3 6.5e-31 106.4 0.3 1.6 2 0 0 2 2 2 1 Cyclin-dependent kinase regulatory subunit Thioredoxin_4 PF13462.6 OAG40598.1 - 7.7e-11 42.4 0.0 2.9e-10 40.5 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin DSBA PF01323.20 OAG40598.1 - 0.11 12.2 0.2 0.24 11.1 0.1 1.6 2 0 0 2 2 2 0 DSBA-like thioredoxin domain Gpr1_Fun34_YaaH PF01184.19 OAG40602.1 - 1.8e-28 99.6 20.1 2.4e-28 99.2 20.1 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Methyltransf_2 PF00891.18 OAG40604.1 - 1.3e-19 70.3 0.0 2e-19 69.8 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain HTH_24 PF13412.6 OAG40604.1 - 0.11 12.1 0.0 0.29 10.7 0.0 1.8 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding Amidohydro_1 PF01979.20 OAG40605.1 - 2.2e-24 86.4 0.3 5.7e-24 85.1 0.3 1.7 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 OAG40605.1 - 1.9e-12 47.5 6.6 2.6e-09 37.1 0.4 3.3 1 1 1 2 2 2 2 Amidohydrolase family Sds3 PF08598.11 OAG40606.1 - 1.1e-30 107.3 12.7 7.8e-30 104.5 12.7 2.1 1 1 0 1 1 1 1 Sds3-like PID_2 PF14719.6 OAG40606.1 - 9.2 6.1 7.5 0.3 11.0 0.5 2.0 3 0 0 3 3 3 0 Phosphotyrosine interaction domain (PTB/PID) Aldose_epim PF01263.20 OAG40607.1 - 3.5e-54 184.1 0.6 4.8e-54 183.7 0.6 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase Sulfate_transp PF00916.20 OAG40609.1 - 9.8e-74 248.4 11.6 1.6e-73 247.7 11.6 1.3 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 OAG40609.1 - 1.7e-06 27.6 0.1 2.6e-05 23.8 0.0 2.3 2 0 0 2 2 2 1 STAS domain MFS_MOT1 PF16983.5 OAG40609.1 - 0.0088 16.4 4.7 0.0088 16.4 4.7 3.0 3 0 0 3 3 3 1 Molybdate transporter of MFS superfamily CNOT1_TTP_bind PF16417.5 OAG40609.1 - 0.016 14.4 0.0 0.028 13.6 0.0 1.3 1 0 0 1 1 1 0 CCR4-NOT transcription complex subunit 1 TTP binding domain Prok-E2_E PF14462.6 OAG40609.1 - 0.24 11.2 0.6 0.47 10.3 0.6 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family E HA2 PF04408.23 OAG40611.1 - 3.8e-23 81.8 1.1 7.5e-22 77.7 0.0 3.2 3 0 0 3 3 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 OAG40611.1 - 4.2e-18 65.5 0.0 2e-17 63.3 0.0 2.1 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 OAG40611.1 - 4.6e-14 52.7 0.0 1.2e-13 51.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 OAG40611.1 - 4.4e-07 29.8 0.1 9.2e-07 28.8 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 OAG40611.1 - 3.5e-05 24.1 0.1 0.0001 22.6 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 OAG40611.1 - 0.00019 21.2 0.0 0.00045 20.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 OAG40611.1 - 0.0004 19.7 0.0 0.00098 18.5 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) SRP54 PF00448.22 OAG40611.1 - 0.00047 19.8 0.2 0.0013 18.4 0.2 1.7 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain T2SSE PF00437.20 OAG40611.1 - 0.00076 18.6 0.0 0.0016 17.6 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.6 OAG40611.1 - 0.00087 19.6 0.2 0.0021 18.4 0.2 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 OAG40611.1 - 0.0051 16.9 0.2 0.037 14.1 0.2 2.4 1 1 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.14 OAG40611.1 - 0.0084 16.1 0.1 0.017 15.1 0.1 1.5 1 0 0 1 1 1 1 Flavivirus DEAD domain ResIII PF04851.15 OAG40611.1 - 0.0093 16.0 0.1 4 7.4 0.0 2.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ATPase PF06745.13 OAG40611.1 - 0.045 13.1 0.0 0.089 12.1 0.0 1.4 1 0 0 1 1 1 0 KaiC Microtub_bd PF16796.5 OAG40611.1 - 0.054 13.4 0.0 0.3 11.0 0.0 2.1 2 0 0 2 2 2 0 Microtubule binding Zeta_toxin PF06414.12 OAG40611.1 - 0.07 12.4 0.2 0.26 10.5 0.1 2.0 1 1 1 2 2 2 0 Zeta toxin AAA_25 PF13481.6 OAG40611.1 - 0.075 12.6 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 OAG40611.1 - 0.1 13.0 0.0 0.33 11.3 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 OAG40611.1 - 0.11 12.0 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 OAG40611.1 - 0.11 12.4 2.1 1 9.2 0.3 2.9 3 0 0 3 3 3 0 NACHT domain AAA_24 PF13479.6 OAG40611.1 - 0.13 12.0 0.0 0.36 10.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 OAG40611.1 - 0.13 11.8 0.2 0.57 9.7 0.1 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Glug PF07581.12 OAG40611.1 - 0.17 12.3 0.0 0.46 11.0 0.0 1.7 1 0 0 1 1 1 0 The GLUG motif AAA_33 PF13671.6 OAG40611.1 - 0.2 11.8 0.1 0.2 11.8 0.1 2.6 3 1 0 3 3 2 0 AAA domain Pkinase PF00069.25 OAG40612.1 - 2.7e-54 184.3 0.0 4.4e-54 183.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG40612.1 - 1.9e-37 128.9 0.0 3e-37 128.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAG40612.1 - 0.0089 15.4 0.0 0.016 14.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OAG40612.1 - 0.011 14.6 0.1 0.052 12.3 0.0 2.0 2 0 0 2 2 2 0 Fungal protein kinase Asparaginase PF00710.20 OAG40613.1 - 4.6e-26 91.5 0.2 1.2e-24 86.9 0.0 2.1 2 0 0 2 2 2 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 OAG40613.1 - 6.8e-15 55.3 0.1 1.4e-14 54.2 0.1 1.6 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain Sugar_tr PF00083.24 OAG40614.1 - 5e-19 68.5 25.5 6.4e-11 41.8 6.4 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter DUF624 PF04854.14 OAG40614.1 - 0.048 13.8 1.0 1.2 9.3 0.1 3.2 2 0 0 2 2 2 0 Protein of unknown function, DUF624 TMEM213 PF15192.6 OAG40614.1 - 0.59 10.1 4.5 3.2 7.8 1.6 2.6 2 0 0 2 2 2 0 TMEM213 family FeS_assembly_P PF01883.19 OAG40615.1 - 1.9e-08 34.4 0.0 5.3e-08 32.9 0.0 1.9 1 1 0 1 1 1 1 Iron-sulfur cluster assembly protein Zn_clus PF00172.18 OAG40616.1 - 7.7e-06 25.9 9.2 1.2e-05 25.3 9.2 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4490 PF14892.6 OAG40616.1 - 0.037 14.1 4.1 0.066 13.3 4.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4490) Fungal_trans PF04082.18 OAG40616.1 - 0.039 13.0 0.1 0.063 12.3 0.1 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain Sel_put PF04328.13 OAG40616.1 - 0.34 11.0 2.7 2.6 8.1 0.1 2.7 2 0 0 2 2 2 0 Selenoprotein, putative Sybindin PF04099.12 OAG40618.1 - 4.3e-37 127.2 0.0 6.5e-37 126.6 0.0 1.3 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 OAG40618.1 - 0.0028 17.8 0.0 0.0048 17.0 0.0 1.4 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region VWA_2 PF13519.6 OAG40619.1 - 8.9e-21 74.6 0.0 2.4e-20 73.1 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 OAG40619.1 - 1.9e-08 34.7 0.2 2.9e-08 34.2 0.2 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.14 OAG40619.1 - 1.4e-05 25.0 0.1 2e-05 24.5 0.1 1.2 1 0 0 1 1 1 1 Ssl1-like UIM PF02809.20 OAG40619.1 - 0.012 15.4 2.1 0.041 13.8 2.1 1.9 1 0 0 1 1 1 0 Ubiquitin interaction motif ANAPC_CDC26 PF10471.9 OAG40620.1 - 1.2e-11 45.3 0.2 2.5e-08 34.6 0.1 2.1 2 0 0 2 2 2 2 Anaphase-promoting complex APC subunit CDC26 HTH_Tnp_Tc5 PF03221.16 OAG40621.1 - 1.5e-05 24.9 0.0 4.3e-05 23.5 0.0 1.8 1 1 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.16 OAG40621.1 - 0.14 11.9 0.2 0.27 11.0 0.2 1.5 1 0 0 1 1 1 0 helix-turn-helix, Psq domain FaeA PF04703.12 OAG40621.1 - 0.14 12.5 0.1 0.25 11.7 0.1 1.4 1 0 0 1 1 1 0 FaeA-like protein CorA PF01544.18 OAG40622.1 - 0.00048 19.5 0.1 0.0013 18.2 0.1 1.6 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein TFIIS_M PF07500.14 OAG40624.1 - 1e-28 100.0 0.3 2.1e-28 99.0 0.3 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 OAG40624.1 - 7.4e-19 67.3 5.4 1.1e-18 66.7 5.4 1.3 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 OAG40624.1 - 2.2e-12 46.8 0.1 5.7e-12 45.5 0.1 1.7 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Cytochrom_NNT PF03264.14 OAG40624.1 - 0.04 13.6 5.7 0.064 12.9 5.7 1.3 1 0 0 1 1 1 0 NapC/NirT cytochrome c family, N-terminal region PSCyt2 PF07583.11 OAG40624.1 - 0.068 13.1 0.1 0.12 12.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1549) Cytochrome_C7 PF14522.6 OAG40624.1 - 1 9.4 9.1 2.8 8.0 9.2 1.6 1 1 0 1 1 1 0 Cytochrome c7 and related cytochrome c FAD_binding_2 PF00890.24 OAG40625.1 - 9.4e-81 272.0 0.4 1.1e-80 271.7 0.4 1.1 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.28 OAG40625.1 - 5.3e-22 77.8 0.1 4.5e-20 71.6 0.0 3.2 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.24 OAG40625.1 - 4.7e-13 49.5 0.1 7.9e-13 48.7 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 OAG40625.1 - 1.2e-08 34.7 0.6 6.3e-08 32.4 0.4 2.2 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAG40625.1 - 1.7e-08 34.5 1.0 1.2e-07 31.8 0.2 2.7 2 1 1 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAG40625.1 - 1.4e-05 24.5 0.2 4.6e-05 22.8 0.1 2.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG40625.1 - 4.2e-05 22.9 0.0 0.2 10.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAG40625.1 - 0.00019 20.3 2.4 0.00054 18.8 0.4 2.5 2 1 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 OAG40625.1 - 0.0009 18.4 1.4 0.16 11.1 0.5 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.17 OAG40625.1 - 0.0015 17.8 0.3 0.058 12.6 0.1 2.4 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 OAG40625.1 - 0.0044 16.3 0.0 0.0066 15.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 OAG40625.1 - 0.011 15.0 0.1 0.023 14.0 0.1 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Amino_oxidase PF01593.24 OAG40625.1 - 0.026 13.8 0.6 1.2 8.4 0.1 2.9 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase GDI PF00996.18 OAG40625.1 - 0.1 11.1 0.1 0.18 10.3 0.1 1.3 1 0 0 1 1 1 0 GDP dissociation inhibitor Pyr_redox PF00070.27 OAG40625.1 - 0.15 12.6 0.6 5.4 7.7 0.3 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Epimerase PF01370.21 OAG40626.1 - 2.2e-09 37.1 0.0 6.7e-09 35.6 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OAG40626.1 - 7.4e-09 35.0 0.0 1.2e-08 34.3 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 OAG40626.1 - 6.4e-08 32.7 0.0 9.8e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 OAG40626.1 - 3e-06 26.9 0.0 9.3e-06 25.3 0.0 1.8 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 OAG40626.1 - 5e-06 25.9 0.0 0.00079 18.7 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein NmrA PF05368.13 OAG40626.1 - 0.0015 18.1 0.1 0.0027 17.3 0.1 1.5 1 1 0 1 1 1 1 NmrA-like family Fungal_trans_2 PF11951.8 OAG40627.1 - 4.7e-08 32.3 3.1 8.1e-08 31.5 3.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pro_isomerase PF00160.21 OAG40628.1 - 1.2e-45 155.6 0.1 1.4e-45 155.4 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF3752 PF12572.8 OAG40630.1 - 7.7e-46 156.4 8.5 7.7e-46 156.4 8.5 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3752) Dynamitin PF04912.14 OAG40630.1 - 0.045 13.1 0.1 0.058 12.7 0.1 1.3 1 0 0 1 1 1 0 Dynamitin Zn_clus PF00172.18 OAG40631.1 - 6.9e-05 22.9 5.0 0.00016 21.7 5.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AAA_34 PF13872.6 OAG40631.1 - 0.17 10.8 0.0 0.26 10.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 Thioredoxin PF00085.20 OAG40632.1 - 1.4e-30 105.3 0.0 1.6e-25 89.1 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.6 OAG40632.1 - 9e-06 25.7 0.0 0.00021 21.3 0.0 2.3 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_2 PF13098.6 OAG40632.1 - 0.0023 18.4 0.0 0.057 13.9 0.0 2.6 2 0 0 2 2 2 1 Thioredoxin-like domain OST3_OST6 PF04756.13 OAG40632.1 - 0.0029 17.0 0.0 0.006 16.0 0.0 1.4 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family TraF PF13728.6 OAG40632.1 - 0.0079 16.0 11.8 0.008 16.0 0.0 4.1 5 0 0 5 5 5 1 F plasmid transfer operon protein Thioredoxin_7 PF13899.6 OAG40632.1 - 0.021 15.0 0.0 0.047 13.9 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_8 PF13905.6 OAG40632.1 - 0.024 14.9 0.0 10 6.5 0.0 3.8 3 1 1 4 4 4 0 Thioredoxin-like AhpC-TSA PF00578.21 OAG40632.1 - 0.029 14.3 0.0 0.1 12.5 0.0 1.8 2 0 0 2 2 2 0 AhpC/TSA family GNAT_acetyltr_2 PF13718.6 OAG40634.1 - 2.5e-98 328.0 0.0 4.6e-98 327.2 0.0 1.5 1 0 0 1 1 1 1 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.6 OAG40634.1 - 2.5e-79 266.3 0.0 3.8e-79 265.7 0.0 1.3 1 0 0 1 1 1 1 Possible tRNA binding domain Helicase_RecD PF05127.14 OAG40634.1 - 1.2e-65 220.7 0.0 4.9e-65 218.7 0.0 1.9 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.11 OAG40634.1 - 3.6e-34 116.6 0.2 1.1e-33 115.0 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1726) AAA_30 PF13604.6 OAG40634.1 - 0.00023 21.0 0.1 0.037 13.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain GHMP_kinases_N PF00288.26 OAG40634.1 - 0.14 12.4 0.1 0.42 10.9 0.1 1.8 1 0 0 1 1 1 0 GHMP kinases N terminal domain Glyco_transf_90 PF05686.12 OAG40635.1 - 1.4e-12 47.3 0.7 2.7e-08 33.2 0.2 3.4 2 1 0 2 2 2 2 Glycosyl transferase family 90 DUF2474 PF10617.9 OAG40635.1 - 3.8 7.4 5.7 5.8 6.8 1.8 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2474) Ada_Zn_binding PF02805.16 OAG40636.1 - 2.5e-29 101.1 5.8 4.5e-29 100.3 5.8 1.4 1 0 0 1 1 1 1 Metal binding domain of Ada HTH_AraC PF00165.23 OAG40636.1 - 7.2e-07 29.2 0.0 1.6e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_18 PF12833.7 OAG40636.1 - 0.00031 20.9 0.0 0.00068 19.9 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain Glyoxalase PF00903.25 OAG40637.1 - 0.21 11.8 0.0 0.21 11.8 0.0 2.8 2 1 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily GREB1 PF15782.5 OAG40637.1 - 6.8 3.7 17.3 10 3.1 17.3 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer EMG1 PF03587.14 OAG40638.1 - 8.4e-80 267.0 0.0 9.8e-80 266.8 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase RP854 PF17460.2 OAG40638.1 - 0.063 13.0 0.1 0.12 12.2 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein RP854 PIP5K PF01504.18 OAG40639.1 - 3.3e-97 325.0 0.0 7.7e-97 323.8 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Na_Ca_ex PF01699.24 OAG40640.1 - 2.4e-25 89.3 28.2 1.5e-13 51.0 10.1 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Fungal_trans PF04082.18 OAG40641.1 - 3.8e-14 52.4 0.1 3.8e-14 52.4 0.1 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG40641.1 - 3.4e-06 27.1 11.8 5.4e-06 26.4 11.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HSBP1 PF06825.12 OAG40641.1 - 0.096 12.6 0.1 0.18 11.7 0.1 1.4 1 0 0 1 1 1 0 Heat shock factor binding protein 1 mono-CXXC PF15626.6 OAG40642.1 - 0.99 9.8 4.6 1.3 9.4 0.2 2.6 2 0 0 2 2 2 0 single CXXC unit Dor1 PF04124.12 OAG40643.1 - 1.4e-44 152.2 5.0 3.4e-32 111.5 3.1 2.2 2 0 0 2 2 2 2 Dor1-like family Spt5_N PF11942.8 OAG40643.1 - 0.67 11.0 6.6 1.9 9.5 6.6 1.8 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal His_Phos_1 PF00300.22 OAG40644.1 - 1.1e-28 100.3 0.6 3.7e-28 98.5 0.2 2.1 2 1 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) SWIB PF02201.18 OAG40645.1 - 3.5e-21 74.9 0.0 1.8e-20 72.6 0.0 2.2 2 0 0 2 2 2 1 SWIB/MDM2 domain E2F_CC-MB PF16421.5 OAG40645.1 - 0.017 15.4 1.0 3.8 7.9 0.3 2.7 2 0 0 2 2 2 0 E2F transcription factor CC-MB domain Sulfatase_C PF14707.6 OAG40645.1 - 3.1 8.5 6.8 0.48 11.2 0.2 2.9 3 1 1 4 4 4 0 C-terminal region of aryl-sulfatase RNase_T PF00929.24 OAG40646.1 - 2.4e-13 51.0 0.0 3e-13 50.7 0.0 1.1 1 0 0 1 1 1 1 Exonuclease PGM_PMM_I PF02878.16 OAG40648.1 - 5.5e-31 107.1 0.0 8e-31 106.6 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 OAG40648.1 - 2.6e-24 85.6 0.0 5.7e-24 84.5 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 OAG40648.1 - 4.1e-15 56.3 0.0 8.3e-15 55.3 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 OAG40648.1 - 1.6e-06 28.2 0.0 3.5e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain DUF1275 PF06912.11 OAG40649.1 - 2.4e-44 151.6 8.9 2.8e-44 151.3 8.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) Amidohydro_1 PF01979.20 OAG40650.1 - 7.6e-43 147.1 0.1 8.7e-43 146.9 0.1 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 OAG40650.1 - 6.3e-15 55.6 0.2 9.8e-12 45.1 0.1 2.1 2 0 0 2 2 2 2 Amidohydrolase family LIP PF03583.14 OAG40651.1 - 2.6e-59 200.9 0.1 3.4e-59 200.5 0.1 1.1 1 0 0 1 1 1 1 Secretory lipase Pkinase PF00069.25 OAG40652.1 - 8.5e-55 185.9 0.0 1.1e-54 185.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG40652.1 - 3.1e-34 118.4 0.0 3.8e-34 118.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAG40652.1 - 9e-06 25.2 0.0 0.00012 21.5 0.0 2.0 1 1 1 2 2 2 1 Kinase-like APH PF01636.23 OAG40652.1 - 8.9e-05 22.5 0.1 0.0011 19.0 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 OAG40652.1 - 0.0069 15.8 0.1 0.01 15.2 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OAG40652.1 - 0.13 11.2 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain CYSTM PF12734.7 OAG40653.1 - 8.8e-08 32.3 18.5 8.8e-08 32.3 18.5 4.0 2 2 0 2 2 2 1 Cysteine-rich TM module stress tolerance Ras PF00071.22 OAG40654.1 - 2.9e-11 43.2 0.0 7.7e-10 38.6 0.0 2.0 2 0 0 2 2 2 2 Ras family G-alpha PF00503.20 OAG40654.1 - 0.25 10.5 0.0 0.37 9.9 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit DUF2196 PF09962.9 OAG40655.1 - 3.9e-23 81.2 3.9 3.9e-23 81.2 3.9 2.2 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2196) L27_1 PF09058.10 OAG40655.1 - 0.034 14.1 1.0 0.086 12.8 1.0 1.7 1 0 0 1 1 1 0 L27_1 TFIIA PF03153.13 OAG40655.1 - 0.054 13.5 30.6 0.061 13.3 30.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Neur_chan_memb PF02932.16 OAG40655.1 - 4 7.4 8.8 5.2 7.1 8.8 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region NmrA PF05368.13 OAG40657.1 - 2.1e-14 53.7 0.0 3.2e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG40657.1 - 2.3e-12 47.2 0.5 3.8e-12 46.5 0.5 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAG40657.1 - 7.1e-05 22.4 0.1 0.00011 21.7 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.20 OAG40657.1 - 0.00016 21.8 0.0 0.00024 21.2 0.0 1.3 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus 3Beta_HSD PF01073.19 OAG40657.1 - 0.0016 17.5 0.0 0.0068 15.4 0.0 1.9 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.17 OAG40657.1 - 0.0018 18.8 0.6 0.0036 17.9 0.6 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 OAG40657.1 - 0.0037 16.9 0.2 0.0075 15.9 0.2 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Semialdhyde_dh PF01118.24 OAG40657.1 - 0.0046 17.4 0.1 0.0086 16.5 0.1 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.10 OAG40657.1 - 0.0083 16.1 0.1 0.013 15.4 0.1 1.3 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.20 OAG40657.1 - 0.01 15.9 0.0 0.019 15.0 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase RmlD_sub_bind PF04321.17 OAG40657.1 - 0.015 14.4 0.1 0.032 13.3 0.1 1.5 1 0 0 1 1 1 0 RmlD substrate binding domain CoA_binding PF02629.19 OAG40657.1 - 0.032 14.9 0.3 0.071 13.8 0.3 1.5 1 0 0 1 1 1 0 CoA binding domain TrkA_N PF02254.18 OAG40657.1 - 0.041 14.1 0.1 0.072 13.3 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain GFO_IDH_MocA PF01408.22 OAG40657.1 - 0.049 14.5 0.1 0.082 13.7 0.1 1.3 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Ldh_1_N PF00056.23 OAG40657.1 - 0.15 12.1 0.6 0.29 11.2 0.6 1.5 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Abhydrolase_6 PF12697.7 OAG40658.1 - 6.8e-11 43.2 0.0 9.3e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG40658.1 - 1.8e-09 37.2 0.1 8.1e-09 35.1 0.1 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OAG40658.1 - 2.7e-08 33.8 0.0 6.6e-07 29.2 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold adh_short_C2 PF13561.6 OAG40659.1 - 1.1e-53 182.2 0.0 1.4e-53 181.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG40659.1 - 3.5e-42 144.1 0.0 4.4e-42 143.7 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG40659.1 - 9.5e-09 35.4 0.0 2.3e-08 34.2 0.0 1.6 2 1 0 2 2 2 1 KR domain Epimerase PF01370.21 OAG40659.1 - 1.6e-06 27.8 0.1 6.8e-06 25.7 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 OAG40659.1 - 0.012 14.7 0.0 0.021 14.0 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain 3Beta_HSD PF01073.19 OAG40659.1 - 0.016 14.2 0.0 0.023 13.7 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.18 OAG40659.1 - 0.039 14.2 0.0 0.074 13.3 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Polysacc_synt_2 PF02719.15 OAG40659.1 - 0.053 12.7 0.0 0.078 12.1 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Methyltransf_25 PF13649.6 OAG40659.1 - 0.054 14.2 0.1 0.11 13.2 0.1 1.5 1 1 0 1 1 1 0 Methyltransferase domain NAD_binding_4 PF07993.12 OAG40659.1 - 0.088 12.0 0.0 0.13 11.4 0.0 1.5 1 1 0 1 1 1 0 Male sterility protein CAT_RBD PF03123.15 OAG40659.1 - 0.14 12.1 0.0 2.4 8.2 0.1 2.2 2 0 0 2 2 2 0 CAT RNA binding domain Ribosomal_S15 PF00312.22 OAG40660.1 - 1e-25 89.7 0.3 7.2e-25 87.0 0.3 2.3 2 0 0 2 2 2 1 Ribosomal protein S15 Ribosomal_S2 PF00318.20 OAG40661.1 - 1e-27 96.8 0.1 2.2e-15 56.5 0.1 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 OAG40661.1 - 0.00011 23.5 10.0 0.0002 22.6 10.0 1.5 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus DUF1075 PF06388.11 OAG40662.1 - 4.9 7.2 6.1 3.2 7.8 1.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1075) Glyco_hyd_65N_2 PF14498.6 OAG40663.1 - 1.7e-40 139.4 0.0 2.5e-40 138.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain DUF3332 PF11810.8 OAG40663.1 - 0.012 15.3 0.2 0.096 12.3 0.2 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF3332) MR_MLE_C PF13378.6 OAG40664.1 - 1.2e-54 185.2 0.2 2.2e-54 184.3 0.1 1.4 2 0 0 2 2 2 1 Enolase C-terminal domain-like MAAL_C PF07476.11 OAG40664.1 - 0.00012 21.3 0.0 0.00019 20.7 0.0 1.2 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus MR_MLE_N PF02746.16 OAG40664.1 - 0.00066 19.9 0.0 0.0014 18.8 0.0 1.6 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Fungal_trans PF04082.18 OAG40665.1 - 4.7e-25 88.1 0.0 1.1e-24 87.0 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG40665.1 - 3.3e-08 33.5 12.2 6.8e-08 32.5 12.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2HC5 PF06221.13 OAG40665.1 - 0.1 12.6 2.3 0.3 11.1 2.3 1.8 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type Lipase_GDSL_2 PF13472.6 OAG40666.1 - 1.1e-24 87.8 0.2 1.8e-22 80.6 0.2 2.1 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 OAG40666.1 - 1.3e-16 61.2 0.0 2e-16 60.6 0.0 1.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase AP_endonuc_2 PF01261.24 OAG40666.1 - 0.028 13.9 0.0 0.086 12.3 0.0 1.8 2 1 0 2 2 2 0 Xylose isomerase-like TIM barrel LpxI_N PF17930.1 OAG40666.1 - 0.089 12.7 0.0 0.43 10.5 0.0 2.0 2 0 0 2 2 2 0 LpxI N-terminal domain Sugar_tr PF00083.24 OAG40667.1 - 4.1e-72 243.5 18.1 4.8e-72 243.3 18.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG40667.1 - 7.4e-13 48.1 27.3 2.1e-09 36.8 24.6 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily BRI3BP PF14965.6 OAG40667.1 - 0.057 12.9 0.1 0.11 12.0 0.1 1.4 1 0 0 1 1 1 0 Negative regulator of p53/TP53 Epimerase PF01370.21 OAG40668.1 - 1.3e-12 47.7 0.1 6e-12 45.5 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 OAG40668.1 - 5.9e-07 29.6 0.6 8.7e-07 29.0 0.6 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 OAG40668.1 - 4.2e-05 23.2 0.2 6.2e-05 22.7 0.2 1.2 1 0 0 1 1 1 1 NmrA-like family TrkA_N PF02254.18 OAG40668.1 - 0.00054 20.2 0.3 0.0017 18.6 0.1 1.9 3 0 0 3 3 3 1 TrkA-N domain AlaDh_PNT_C PF01262.21 OAG40668.1 - 0.00067 19.0 0.3 0.00067 19.0 0.3 1.5 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.16 OAG40668.1 - 0.0013 18.4 0.0 0.0023 17.6 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3Beta_HSD PF01073.19 OAG40668.1 - 0.0016 17.5 0.0 0.0084 15.1 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 OAG40668.1 - 0.0021 17.5 0.0 0.47 9.8 0.0 2.4 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase NAD_binding_2 PF03446.15 OAG40668.1 - 0.015 15.5 0.1 0.025 14.8 0.1 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 OAG40668.1 - 0.015 15.2 0.1 0.023 14.6 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 OAG40668.1 - 0.049 13.7 0.1 0.082 13.0 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase MOSC PF03473.17 OAG40669.1 - 1.8e-23 83.0 0.0 3.1e-23 82.2 0.0 1.4 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 OAG40669.1 - 9.3e-14 51.3 0.0 1.8e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain EPSP_synthase PF00275.20 OAG40670.1 - 7.3e-131 436.7 0.0 1.6e-130 435.5 0.0 1.6 2 0 0 2 2 2 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.20 OAG40670.1 - 2.6e-97 325.1 0.0 4.7e-97 324.3 0.0 1.4 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.15 OAG40670.1 - 1e-57 196.0 0.0 2.6e-57 194.7 0.0 1.7 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.22 OAG40670.1 - 3.9e-37 127.8 0.4 1.7e-36 125.7 0.0 2.3 2 0 0 2 2 2 1 Shikimate kinase AlaDh_PNT_N PF05222.15 OAG40670.1 - 8e-28 97.4 0.0 2.2e-27 96.0 0.0 1.7 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain Shikimate_dh_N PF08501.11 OAG40670.1 - 4.4e-25 87.7 0.0 1e-24 86.6 0.0 1.7 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Fe-ADH_2 PF13685.6 OAG40670.1 - 1.6e-08 34.6 0.0 3.4e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase AlaDh_PNT_C PF01262.21 OAG40670.1 - 2.4e-05 23.8 0.5 0.011 15.0 0.0 4.3 5 0 0 5 5 5 1 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 OAG40670.1 - 0.0011 19.1 0.0 0.0037 17.3 0.0 1.9 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase SDH_C PF18317.1 OAG40670.1 - 0.0056 16.4 5.3 0.02 14.7 2.5 2.8 3 0 0 3 3 3 1 Shikimate 5'-dehydrogenase C-terminal domain AAA_33 PF13671.6 OAG40670.1 - 0.028 14.6 0.0 0.38 10.9 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.6 OAG40670.1 - 0.14 12.6 0.1 3 8.2 0.0 2.8 2 0 0 2 2 2 0 AAA ATPase domain MAF_flag10 PF01973.18 OAG40670.1 - 0.18 11.5 0.0 0.46 10.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF115 Gar1 PF04410.14 OAG40671.1 - 1.5e-45 154.8 2.0 2.9e-45 153.8 2.0 1.5 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region YL1 PF05764.13 OAG40671.1 - 0.63 10.1 10.3 12 6.0 5.7 2.5 2 0 0 2 2 2 0 YL1 nuclear protein FPN1 PF06963.12 OAG40672.1 - 4.6e-73 246.3 7.6 5.5e-73 246.0 7.6 1.1 1 0 0 1 1 1 1 Ferroportin1 (FPN1) EHN PF06441.12 OAG40673.1 - 6.5e-28 97.3 0.3 1.5e-27 96.1 0.3 1.6 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 OAG40673.1 - 3.8e-09 36.6 0.0 7.4e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG40673.1 - 0.038 14.6 0.2 0.062 13.9 0.2 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family Glyco_transf_22 PF03901.17 OAG40675.1 - 2.7e-86 290.4 17.7 3.5e-86 290.0 17.7 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family DUF3445 PF11927.8 OAG40675.1 - 4.3e-77 258.8 0.0 6.8e-77 258.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) ApoO PF09769.9 OAG40675.1 - 0.078 12.9 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Apolipoprotein O Exo5 PF09810.9 OAG40676.1 - 1.5e-133 445.9 0.0 1.9e-133 445.6 0.0 1.1 1 0 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease PDDEXK_1 PF12705.7 OAG40676.1 - 1.5e-05 25.0 0.5 0.3 10.9 0.0 3.0 3 0 0 3 3 3 2 PD-(D/E)XK nuclease superfamily DUF3799 PF12684.7 OAG40676.1 - 0.042 13.6 0.0 0.092 12.5 0.0 1.4 1 0 0 1 1 1 0 PDDEXK-like domain of unknown function (DUF3799) Mpv17_PMP22 PF04117.12 OAG40677.1 - 1.8e-14 53.7 0.8 3.9e-14 52.6 0.8 1.6 1 0 0 1 1 1 1 Mpv17 / PMP22 family 2Fe-2S_thioredx PF01257.19 OAG40677.1 - 0.078 12.8 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like [2Fe-2S] ferredoxin Histone PF00125.24 OAG40678.1 - 1.2e-45 155.1 7.4 4e-31 108.1 0.3 2.0 1 1 1 2 2 2 2 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 OAG40678.1 - 6.7e-06 26.4 0.0 1.1e-05 25.7 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 OAG40678.1 - 4.3e-05 23.6 0.5 6.7e-05 23.0 0.1 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 OAG40678.1 - 5.5e-05 23.8 1.4 7e-05 23.4 1.4 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 OAG40678.1 - 0.0044 17.3 0.0 0.012 15.9 0.0 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 OAG40678.1 - 0.034 14.2 0.5 0.052 13.6 0.1 1.6 2 1 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 OAG40678.1 - 0.12 12.4 0.2 0.37 10.8 0.0 1.9 2 0 0 2 2 2 0 Bromodomain associated CENP-T_C PF15511.6 OAG40679.1 - 8e-09 35.6 0.1 9.7e-09 35.3 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 OAG40679.1 - 2.4e-05 24.7 0.1 2.8e-05 24.5 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 OAG40679.1 - 7.2e-05 22.9 0.1 0.0001 22.4 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 OAG40679.1 - 0.0002 21.6 0.1 0.00035 20.8 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 OAG40679.1 - 0.0004 20.7 0.1 0.00056 20.2 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 OAG40679.1 - 0.0085 16.2 0.0 0.01 15.9 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 OAG40679.1 - 0.031 14.3 0.0 0.037 14.0 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 OAG40679.1 - 0.052 13.3 0.2 0.064 13.0 0.2 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) HIGH_NTase1_ass PF16581.5 OAG40679.1 - 0.11 12.5 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region zf-C2H2 PF00096.26 OAG40680.1 - 1.8e-09 37.5 15.8 0.00012 22.4 1.4 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAG40680.1 - 2.2e-05 24.9 11.0 0.021 15.6 1.1 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OAG40680.1 - 0.12 12.8 7.1 14 6.3 1.1 3.6 3 0 0 3 3 3 0 Zinc-finger double domain zf-BED PF02892.15 OAG40680.1 - 0.22 11.6 2.0 0.64 10.1 2.0 1.8 1 0 0 1 1 1 0 BED zinc finger zf-Di19 PF05605.12 OAG40680.1 - 2.8 8.3 8.2 0.68 10.3 1.5 2.5 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Metal_resist PF13801.6 OAG40683.1 - 0.0055 16.9 0.3 0.0086 16.3 0.3 1.3 1 0 0 1 1 1 1 Heavy-metal resistance GFA PF04828.14 OAG40684.1 - 4.4e-20 71.8 0.0 6.5e-20 71.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zf-Mss51 PF13824.6 OAG40684.1 - 0.017 15.2 0.0 0.036 14.1 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.18 OAG40684.1 - 0.13 12.4 0.5 0.13 12.4 0.5 2.7 3 0 0 3 3 3 0 MYND finger DnaJ PF00226.31 OAG40685.1 - 1.8e-15 56.8 0.5 5.3e-15 55.3 0.5 1.8 1 0 0 1 1 1 1 DnaJ domain Sec63 PF02889.16 OAG40685.1 - 7.4e-06 25.3 0.0 0.0036 16.5 0.0 2.3 2 0 0 2 2 2 2 Sec63 Brl domain Upf2 PF04050.14 OAG40685.1 - 0.98 10.1 5.1 2.5 8.9 5.1 1.6 1 0 0 1 1 1 0 Up-frameshift suppressor 2 DUF1754 PF08555.10 OAG40685.1 - 2.6 8.9 11.8 1.2 10.0 8.3 2.3 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) LZ_Tnp_IS66 PF13007.7 OAG40685.1 - 3.2 8.6 7.6 33 5.3 0.2 3.8 3 1 0 3 3 3 0 Transposase C of IS166 homeodomain Oxysterol_BP PF01237.18 OAG40686.1 - 9.5e-90 301.1 4.1 1.5e-80 270.8 0.0 2.4 2 1 1 3 3 3 2 Oxysterol-binding protein DUF3605 PF12239.8 OAG40687.1 - 5.6e-55 185.9 2.0 7.4e-55 185.5 2.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) Isochorismatase PF00857.20 OAG40688.1 - 4.4e-23 82.3 0.0 7.6e-23 81.6 0.0 1.4 1 1 0 1 1 1 1 Isochorismatase family TFIIA PF03153.13 OAG40689.1 - 7.1e-62 210.7 3.0 9.5e-62 210.3 3.0 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Bap31 PF05529.12 OAG40690.1 - 6.3e-48 162.1 8.1 1e-47 161.4 8.1 1.3 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 OAG40690.1 - 2.2e-16 59.6 8.4 3.8e-16 58.8 8.4 1.4 1 0 0 1 1 1 1 Bap31/Bap29 cytoplasmic coiled-coil domain Mod_r PF07200.13 OAG40690.1 - 0.0033 17.5 1.9 0.0051 16.9 1.9 1.3 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein DUF4047 PF13256.6 OAG40690.1 - 0.0064 16.7 0.7 0.011 15.9 0.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4047) Cep57_MT_bd PF06657.13 OAG40690.1 - 0.0078 16.6 1.3 0.2 12.1 1.1 2.4 1 1 1 2 2 2 1 Centrosome microtubule-binding domain of Cep57 DUF4337 PF14235.6 OAG40690.1 - 0.016 15.3 2.3 0.016 15.3 2.3 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) YabA PF06156.13 OAG40690.1 - 0.036 14.7 0.3 0.072 13.7 0.3 1.4 1 0 0 1 1 1 0 Initiation control protein YabA Spc7 PF08317.11 OAG40690.1 - 0.043 12.7 1.5 0.056 12.3 1.5 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DivIC PF04977.15 OAG40690.1 - 0.07 12.9 6.0 0.98 9.2 3.6 2.6 2 0 0 2 2 2 0 Septum formation initiator Spc24 PF08286.11 OAG40690.1 - 0.11 12.7 1.4 0.2 11.9 1.4 1.4 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 bZIP_Maf PF03131.17 OAG40690.1 - 0.19 12.3 2.5 0.32 11.6 2.5 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor KELK PF15796.5 OAG40690.1 - 0.37 11.3 6.2 0.94 10.0 6.2 1.7 1 1 0 1 1 1 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase COesterase PF00135.28 OAG40691.1 - 4.2e-78 263.5 0.0 6.1e-78 262.9 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAG40691.1 - 0.00028 20.8 1.3 0.0039 17.1 0.5 2.6 2 1 0 2 2 2 1 alpha/beta hydrolase fold PhoD PF09423.10 OAG40692.1 - 4.1e-115 384.5 5.2 5.2e-115 384.2 5.2 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase PhoD_N PF16655.5 OAG40692.1 - 4.9e-34 116.7 0.2 1.3e-33 115.4 0.1 1.8 2 0 0 2 2 2 1 PhoD-like phosphatase, N-terminal domain Pur_ac_phosph_N PF16656.5 OAG40692.1 - 0.00017 22.1 1.7 0.00033 21.2 0.4 2.2 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain NUDIX PF00293.28 OAG40693.1 - 1.5e-19 70.3 0.1 3.9e-19 69.0 0.1 1.6 1 1 0 1 1 1 1 NUDIX domain Prp18 PF02840.15 OAG40696.1 - 9.8e-54 181.3 0.0 9.8e-54 181.3 0.0 1.9 2 0 0 2 2 2 1 Prp18 domain PRP4 PF08799.11 OAG40696.1 - 1.9e-08 33.7 0.3 1.9e-08 33.7 0.3 3.9 4 1 1 5 5 5 1 pre-mRNA processing factor 4 (PRP4) like DUF3340 PF11818.8 OAG40696.1 - 0.011 15.9 10.8 0.021 15.0 10.8 1.4 1 0 0 1 1 1 0 C-terminal domain of tail specific protease (DUF3340) GalP_UDP_tr_C PF02744.17 OAG40696.1 - 0.039 13.7 0.0 0.087 12.5 0.0 1.5 1 0 0 1 1 1 0 Galactose-1-phosphate uridyl transferase, C-terminal domain DDRGK PF09756.9 OAG40696.1 - 0.3 10.7 15.4 0.53 9.9 15.4 1.4 1 0 0 1 1 1 0 DDRGK domain Atg14 PF10186.9 OAG40696.1 - 1.2 8.1 8.1 2 7.4 8.1 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Noggin PF05806.12 OAG40696.1 - 7.3 6.4 6.0 16 5.4 6.0 1.5 1 0 0 1 1 1 0 Noggin CDC45 PF02724.14 OAG40696.1 - 7.3 4.7 11.0 11 4.1 11.0 1.3 1 0 0 1 1 1 0 CDC45-like protein Ank_2 PF12796.7 OAG40697.1 - 1.6e-65 217.7 0.3 1.8e-12 47.7 0.0 8.5 4 3 5 9 9 9 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAG40697.1 - 4.2e-51 170.7 8.8 1.2e-06 29.0 0.0 11.3 7 2 8 15 15 15 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG40697.1 - 4.5e-40 131.1 9.6 0.013 15.9 0.0 16.9 17 1 1 18 18 18 8 Ankyrin repeat Ank PF00023.30 OAG40697.1 - 2.7e-33 112.9 22.4 0.018 15.5 0.0 14.3 15 0 0 15 15 15 9 Ankyrin repeat Ank_5 PF13857.6 OAG40697.1 - 9e-20 70.5 6.5 0.082 13.3 0.0 11.4 9 3 4 13 13 13 6 Ankyrin repeats (many copies) Clr5 PF14420.6 OAG40697.1 - 1.6e-14 53.9 3.9 3e-14 53.0 3.9 1.4 1 0 0 1 1 1 1 Clr5 domain cNMP_binding PF00027.29 OAG40698.1 - 2.5e-36 123.6 0.0 2.3e-21 75.7 0.0 2.7 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain cNMPbd_u2 PF16643.5 OAG40698.1 - 1.1e-32 113.7 18.1 4.3e-32 111.7 14.3 2.5 2 0 0 2 2 2 1 Unstructured region on cNMP-binding protein LRR_6 PF13516.6 OAG40698.1 - 1.7e-07 30.8 5.4 1.8 8.8 0.0 8.2 9 0 0 9 9 9 2 Leucine Rich repeat LRR_4 PF12799.7 OAG40698.1 - 2.9e-06 27.5 9.9 0.045 14.2 0.1 7.0 6 1 2 9 9 9 1 Leucine Rich repeats (2 copies) F-box-like PF12937.7 OAG40698.1 - 4.2e-05 23.4 0.8 0.00011 22.1 0.2 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 OAG40698.1 - 0.0058 16.5 4.6 0.008 16.0 0.1 3.2 3 0 0 3 3 3 1 F-box domain SAM_Ste50p PF09235.10 OAG40698.1 - 0.16 12.2 0.1 9.7 6.5 0.0 3.3 3 0 0 3 3 3 0 Ste50p, sterile alpha motif LRR_1 PF00560.33 OAG40698.1 - 1.2 9.9 16.3 14 6.7 0.4 7.5 8 1 0 8 8 8 0 Leucine Rich Repeat Tim17 PF02466.19 OAG40699.1 - 9.9e-05 22.7 3.1 0.00016 22.1 3.1 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Melittin PF01372.17 OAG40699.1 - 0.13 12.3 0.2 2.3 8.4 0.2 2.5 2 0 0 2 2 2 0 Melittin Abhydrolase_6 PF12697.7 OAG40701.1 - 0.09 13.4 1.5 0.18 12.4 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase family Fungal_trans_2 PF11951.8 OAG40702.1 - 9.8e-06 24.6 0.1 2.5e-05 23.3 0.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain GST_N_2 PF13409.6 OAG40703.1 - 2.7e-07 30.8 0.0 6.2e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OAG40703.1 - 7.6e-07 29.3 0.0 1.3e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 OAG40703.1 - 1.3e-06 28.6 0.0 2.6e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 OAG40703.1 - 2.3e-06 27.7 0.0 6.2e-06 26.3 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 OAG40703.1 - 0.00028 21.2 0.0 0.00046 20.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAG40703.1 - 0.00065 19.7 0.0 0.0011 18.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain A_deaminase PF00962.22 OAG40704.1 - 1.2e-73 248.3 0.0 1.5e-73 248.0 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase DUF2063 PF09836.9 OAG40704.1 - 0.092 13.0 0.1 0.2 11.9 0.1 1.5 1 0 0 1 1 1 0 Putative DNA-binding domain DUF2981 PF11200.8 OAG40705.1 - 0.13 12.0 2.6 0.23 11.2 2.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) LCAT PF02450.15 OAG40706.1 - 0.0046 16.2 0.0 0.0089 15.2 0.0 1.4 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Hydrolase_4 PF12146.8 OAG40706.1 - 0.006 15.9 0.0 0.012 14.9 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OAG40706.1 - 0.038 14.6 0.0 0.13 12.8 0.0 1.9 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF676 PF05057.14 OAG40706.1 - 0.064 12.8 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Peptidase_S9 PF00326.21 OAG40706.1 - 0.15 11.5 0.0 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Lin-8 PF03353.15 OAG40707.1 - 1.5 8.3 5.7 1.9 8.0 5.7 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Pkinase PF00069.25 OAG40708.1 - 1.4e-49 168.9 0.0 4.6e-49 167.1 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG40708.1 - 2.2e-18 66.5 0.0 1.2e-17 64.0 0.0 2.2 2 1 0 2 2 2 1 Protein tyrosine kinase TAF4 PF05236.14 OAG40709.1 - 1.6e-24 87.1 15.8 5.3e-21 75.6 14.4 2.4 2 1 0 2 2 2 2 Transcription initiation factor TFIID component TAF4 family CPSF73-100_C PF11718.8 OAG40710.1 - 3.6e-80 268.6 0.0 5e-80 268.1 0.0 1.2 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 OAG40710.1 - 2.2e-29 101.9 0.0 4.7e-29 100.9 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.27 OAG40710.1 - 1.1e-18 68.0 0.2 2.2e-18 67.0 0.2 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 OAG40710.1 - 1.3e-18 67.2 0.1 2.3e-18 66.4 0.1 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain RMMBL PF07521.12 OAG40710.1 - 7.9e-11 41.7 0.0 1.8e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 OAG40710.1 - 5.3e-05 22.8 1.3 0.00012 21.7 0.3 2.0 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 OAG40710.1 - 7.5e-05 22.7 0.2 0.00031 20.7 0.0 2.1 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Ribosomal_L28 PF00830.19 OAG40710.1 - 0.078 13.2 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 Ribosomal L28 family adh_short PF00106.25 OAG40711.1 - 3.5e-29 101.7 0.0 1.8e-27 96.1 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG40711.1 - 3.8e-17 62.6 0.1 4.7e-14 52.5 0.1 2.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG40711.1 - 0.1 12.5 0.2 0.41 10.5 0.0 1.9 2 0 0 2 2 2 0 KR domain HEAT PF02985.22 OAG40712.1 - 2.5e-18 64.6 7.9 0.00037 20.5 0.1 9.2 9 0 0 9 9 9 3 HEAT repeat HEAT_2 PF13646.6 OAG40712.1 - 1.1e-09 38.6 7.6 0.0023 18.3 0.1 6.1 4 2 3 7 7 7 4 HEAT repeats IBN_N PF03810.19 OAG40712.1 - 1.8e-09 37.4 0.5 2.5e-08 33.7 0.1 3.2 3 0 0 3 3 3 1 Importin-beta N-terminal domain HEAT_EZ PF13513.6 OAG40712.1 - 1.5e-05 25.4 20.8 3.3e-05 24.3 0.0 7.8 8 4 3 11 11 11 1 HEAT-like repeat Cnd1 PF12717.7 OAG40712.1 - 0.0012 18.9 0.2 0.03 14.4 0.1 3.2 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 OAG40712.1 - 0.021 14.4 1.3 16 5.0 0.0 4.6 3 1 1 4 4 4 0 CLASP N terminal RIX1 PF08167.12 OAG40712.1 - 0.037 13.8 0.0 4.1 7.1 0.0 3.3 2 1 0 2 2 2 0 rRNA processing/ribosome biogenesis Arm PF00514.23 OAG40712.1 - 0.054 13.5 8.8 2.5 8.3 0.0 5.5 7 0 0 7 7 6 0 Armadillo/beta-catenin-like repeat HEAT_PBS PF03130.16 OAG40712.1 - 0.06 14.1 0.0 44 5.2 0.0 4.2 4 0 0 4 4 2 0 PBS lyase HEAT-like repeat Vac14_Fab1_bd PF12755.7 OAG40712.1 - 0.14 12.8 0.6 52 4.5 0.0 4.2 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region A_deamin PF02137.18 OAG40712.1 - 0.17 11.3 0.0 9 5.6 0.0 2.1 2 0 0 2 2 2 0 Adenosine-deaminase (editase) domain NUC173 PF08161.12 OAG40712.1 - 0.79 9.3 3.5 3.4 7.3 0.2 3.4 3 1 0 3 3 3 0 NUC173 domain ANAPC4 PF12896.7 OAG40713.1 - 6.7e-52 176.0 0.0 1.2e-51 175.1 0.0 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 ANAPC4_WD40 PF12894.7 OAG40713.1 - 7.6e-09 35.8 0.0 2.2e-08 34.2 0.0 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain DUF957 PF06117.11 OAG40713.1 - 0.076 12.6 0.2 0.27 10.8 0.0 2.1 2 0 0 2 2 2 0 Enterobacterial protein of unknown function (DUF957) AMPK1_CBM PF16561.5 OAG40714.1 - 0.041 14.1 0.0 1 9.6 0.0 2.5 2 0 0 2 2 2 0 Glycogen recognition site of AMP-activated protein kinase DUF3357 PF11837.8 OAG40714.1 - 0.077 13.5 1.7 0.15 12.5 0.3 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF3357) Peptidase_M14 PF00246.24 OAG40715.1 - 2.9e-72 243.9 0.0 3.6e-72 243.6 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.16 OAG40715.1 - 0.036 14.5 0.0 0.085 13.3 0.0 1.6 1 0 0 1 1 1 0 Carboxypeptidase activation peptide TCTP PF00838.17 OAG40716.1 - 7.6e-59 198.8 1.3 8.6e-59 198.6 1.3 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein Ribosomal_S20p PF01649.18 OAG40716.1 - 0.064 13.9 1.3 0.094 13.4 1.3 1.2 1 0 0 1 1 1 0 Ribosomal protein S20 Put_Phosphatase PF06888.12 OAG40716.1 - 0.17 11.2 0.1 0.25 10.7 0.1 1.2 1 0 0 1 1 1 0 Putative Phosphatase FA_hydroxylase PF04116.13 OAG40717.1 - 5.8e-23 81.7 13.7 5.8e-23 81.7 13.7 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Med3 PF11593.8 OAG40718.1 - 1.9 7.6 6.6 5.3 6.1 6.6 1.7 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Lactamase_B_4 PF13691.6 OAG40719.1 - 2.4e-23 81.5 0.1 3.3e-21 74.7 0.1 2.5 2 0 0 2 2 2 2 tRNase Z endonuclease Lactamase_B_2 PF12706.7 OAG40719.1 - 4.2e-12 46.0 0.2 3.6e-11 43.0 0.2 2.3 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 OAG40719.1 - 5e-05 23.4 0.0 0.00022 21.3 0.0 2.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily bZIP_1 PF00170.21 OAG40720.1 - 5e-09 36.1 12.6 5e-09 36.1 12.6 2.3 2 1 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 OAG40720.1 - 0.0038 17.3 15.5 0.0038 17.3 15.5 2.7 3 1 0 3 3 3 1 Basic region leucine zipper PilO PF04350.13 OAG40720.1 - 0.0039 17.3 2.1 0.0039 17.3 2.1 2.2 3 0 0 3 3 3 1 Pilus assembly protein, PilO bZIP_Maf PF03131.17 OAG40720.1 - 0.026 15.1 9.7 0.026 15.1 9.7 2.7 3 0 0 3 3 3 0 bZIP Maf transcription factor Chibby PF14645.6 OAG40720.1 - 0.027 14.9 2.8 0.099 13.1 2.9 1.9 1 1 0 1 1 1 0 Chibby family K-box PF01486.17 OAG40720.1 - 0.064 13.4 5.6 0.26 11.5 5.6 2.0 1 0 0 1 1 1 0 K-box region FlaC_arch PF05377.11 OAG40720.1 - 0.16 12.4 0.2 0.48 10.8 0.2 1.8 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) DivIC PF04977.15 OAG40720.1 - 7.3 6.4 14.2 0.3 10.9 3.5 2.5 2 0 0 2 2 2 0 Septum formation initiator MctB PF11382.8 OAG40720.1 - 7.4 6.2 7.2 0.98 9.1 1.1 2.1 2 0 0 2 2 2 0 Copper transport outer membrane protein, MctB V_ATPase_I PF01496.19 OAG40720.1 - 9.5 4.0 10.0 0.36 8.7 4.0 1.5 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Mob_synth_C PF06463.13 OAG40721.1 - 1.4e-37 128.5 0.1 1.5e-36 125.1 0.0 2.2 2 0 0 2 2 2 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 OAG40721.1 - 1.9e-27 96.7 0.1 3.3e-27 95.9 0.1 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 OAG40721.1 - 9.7e-09 35.6 0.0 2.1e-06 28.1 0.0 2.3 2 0 0 2 2 2 2 4Fe-4S single cluster domain Fer4_14 PF13394.6 OAG40721.1 - 0.002 18.3 0.1 0.071 13.2 0.0 2.5 2 0 0 2 2 2 1 4Fe-4S single cluster domain Ribosomal_L23eN PF03939.13 OAG40721.1 - 0.4 10.9 3.4 1.2 9.4 2.9 2.0 2 0 0 2 2 2 0 Ribosomal protein L23, N-terminal domain MoaC PF01967.21 OAG40722.1 - 1.7e-41 141.5 0.1 3e-41 140.7 0.1 1.4 1 0 0 1 1 1 1 MoaC family F-box-like PF12937.7 OAG40723.1 - 3.7e-09 36.3 0.3 8.7e-09 35.1 0.3 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAG40723.1 - 0.017 15.0 0.6 0.053 13.4 0.6 1.9 1 0 0 1 1 1 0 F-box domain F-box_4 PF15966.5 OAG40723.1 - 0.025 14.5 0.0 0.054 13.4 0.0 1.6 1 0 0 1 1 1 0 F-box PRANC PF09372.10 OAG40723.1 - 0.054 13.8 0.3 0.14 12.5 0.0 1.9 2 0 0 2 2 2 0 PRANC domain Gtr1_RagA PF04670.12 OAG40724.1 - 9.3e-70 234.6 0.6 1.6e-69 233.8 0.6 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 OAG40724.1 - 2.6e-05 23.7 0.0 5.4e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 OAG40724.1 - 0.00039 20.6 0.0 0.001 19.3 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 OAG40724.1 - 0.0013 18.4 0.6 0.0024 17.4 0.1 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OAG40724.1 - 0.0022 18.1 0.1 0.01 15.9 0.0 2.2 3 0 0 3 3 3 1 50S ribosome-binding GTPase AAA_16 PF13191.6 OAG40724.1 - 0.016 15.6 0.0 0.034 14.5 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain SRPRB PF09439.10 OAG40724.1 - 0.018 14.5 0.0 0.048 13.1 0.0 1.7 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit G-alpha PF00503.20 OAG40724.1 - 0.032 13.4 0.7 0.059 12.5 0.7 1.6 1 1 0 1 1 1 0 G-protein alpha subunit Ras PF00071.22 OAG40724.1 - 0.071 12.7 0.1 0.25 10.9 0.1 1.9 1 1 1 2 2 2 0 Ras family Hexapep PF00132.24 OAG40725.1 - 1.4e-06 27.8 14.1 0.026 14.2 3.4 4.3 1 1 3 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.12 OAG40725.1 - 3.5e-06 26.2 0.2 5.8e-06 25.5 0.2 1.2 1 0 0 1 1 1 1 L-fucokinase NTP_transf_3 PF12804.7 OAG40725.1 - 0.00068 20.0 0.0 0.0015 18.9 0.0 1.6 1 0 0 1 1 1 1 MobA-like NTP transferase domain DUF4954 PF16314.5 OAG40725.1 - 0.0054 14.9 2.1 0.0076 14.4 2.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) DUF5554 PF17709.1 OAG40725.1 - 0.1 12.7 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5554) Hexapep_2 PF14602.6 OAG40725.1 - 7.8 6.3 8.1 6.7 6.6 1.2 3.0 1 1 2 3 3 3 0 Hexapeptide repeat of succinyl-transferase SET PF00856.28 OAG40726.1 - 2.5e-17 63.8 0.3 1.3e-16 61.4 0.1 2.3 2 1 0 2 2 2 1 SET domain Pre-SET PF05033.16 OAG40726.1 - 1.5e-15 57.7 5.7 2.3e-14 54.0 2.9 2.4 2 0 0 2 2 2 2 Pre-SET motif bZIP_1 PF00170.21 OAG40727.1 - 4.2e-05 23.6 1.2 0.00011 22.2 1.2 1.7 1 0 0 1 1 1 1 bZIP transcription factor TBK1_CCD1 PF18394.1 OAG40727.1 - 0.073 12.6 0.1 0.12 11.9 0.1 1.2 1 0 0 1 1 1 0 TANK-binding kinase 1 coiled-coil domain 1 bZIP_Maf PF03131.17 OAG40727.1 - 0.21 12.1 6.3 0.23 12.0 4.7 1.9 1 1 0 1 1 1 0 bZIP Maf transcription factor Ion_trans PF00520.31 OAG40729.1 - 5.3e-126 418.8 78.6 3.6e-40 137.7 0.1 4.7 4 1 0 4 4 4 4 Ion transport protein GPHH PF16905.5 OAG40729.1 - 5.5e-05 22.8 0.0 0.00015 21.4 0.0 1.8 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated EF-hand_1 PF00036.32 OAG40729.1 - 0.00026 20.3 0.0 0.0008 18.8 0.0 1.9 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 OAG40729.1 - 0.0064 16.3 0.0 0.025 14.5 0.0 2.1 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 OAG40729.1 - 0.093 13.2 0.0 0.23 11.9 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain pair DUF1645 PF07816.11 OAG40730.1 - 0.074 13.6 0.1 0.15 12.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1645) PAF-AH_p_II PF03403.13 OAG40731.1 - 2e-39 135.2 0.0 6.4e-35 120.4 0.0 2.4 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 OAG40731.1 - 0.0012 17.8 0.1 0.0024 16.9 0.1 1.5 1 1 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 OAG40731.1 - 0.063 12.5 0.1 0.19 10.9 0.0 1.8 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Chlorophyllase PF07224.11 OAG40731.1 - 0.098 11.6 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase KAR9 PF08580.10 OAG40731.1 - 2.9 6.3 11.0 4.8 5.6 11.0 1.3 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Apt1 PF10351.9 OAG40731.1 - 5.6 5.7 6.7 8.7 5.1 6.7 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Ras PF00071.22 OAG40732.1 - 8.1e-49 165.3 0.0 9.8e-49 165.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAG40732.1 - 5e-29 101.0 0.0 1.3e-28 99.6 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAG40732.1 - 8.2e-10 38.4 0.0 1.1e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.22 OAG40732.1 - 0.00061 20.2 0.1 0.0035 17.7 0.1 2.0 1 1 0 1 1 1 1 RNA helicase MMR_HSR1 PF01926.23 OAG40732.1 - 0.0012 18.9 0.0 0.0021 18.1 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OAG40732.1 - 0.0052 16.2 0.0 0.0068 15.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Pox_A32 PF04665.12 OAG40732.1 - 0.02 14.3 0.1 0.037 13.5 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein G-alpha PF00503.20 OAG40732.1 - 0.021 14.0 1.3 1.4 8.0 0.1 2.4 2 1 1 3 3 3 0 G-protein alpha subunit RsgA_GTPase PF03193.16 OAG40732.1 - 0.027 14.4 0.1 7.9 6.4 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_7 PF12775.7 OAG40732.1 - 0.034 13.7 0.0 0.058 12.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 OAG40732.1 - 0.065 12.9 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 OAG40732.1 - 0.068 13.2 0.1 0.14 12.1 0.1 1.6 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 OAG40732.1 - 0.11 12.6 0.2 0.22 11.7 0.2 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 OAG40732.1 - 0.13 12.6 0.0 0.22 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Nas2_N PF18265.1 OAG40733.1 - 9.7e-30 102.3 0.1 1.4e-29 101.8 0.1 1.3 1 0 0 1 1 1 1 Nas2 N_terminal domain PDZ_2 PF13180.6 OAG40733.1 - 1.5e-05 25.3 0.0 2.8e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.14 OAG40733.1 - 3.6e-05 24.1 0.0 6.2e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain PDZ_6 PF17820.1 OAG40733.1 - 6.1e-05 22.8 0.0 0.00011 22.0 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 OAG40733.1 - 0.0012 19.1 0.0 0.0025 18.1 0.0 1.5 1 0 0 1 1 1 1 PDZ domain RhoGEF PF00621.20 OAG40734.1 - 2.4e-27 96.4 0.0 4.2e-27 95.6 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain FAD_binding_3 PF01494.19 OAG40735.1 - 3.3e-21 75.9 0.3 7.2e-19 68.2 0.3 2.4 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAG40735.1 - 2.9e-07 30.4 5.9 7.2e-06 25.8 1.1 2.3 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAG40735.1 - 3.2e-07 30.5 0.4 7.2e-07 29.4 0.4 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 OAG40735.1 - 5.8e-06 25.7 0.2 9.9e-06 24.9 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.14 OAG40735.1 - 8.8e-05 21.5 0.0 0.00015 20.8 0.0 1.3 1 0 0 1 1 1 1 Tryptophan halogenase Pyr_redox PF00070.27 OAG40735.1 - 0.00018 22.0 0.1 0.00073 20.0 0.2 1.9 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 OAG40735.1 - 0.00021 20.8 0.4 0.0004 19.9 0.4 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG40735.1 - 0.00023 20.5 0.1 0.00041 19.7 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAG40735.1 - 0.00087 18.1 0.2 0.0013 17.6 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.22 OAG40735.1 - 0.0037 16.4 0.6 0.0052 15.9 0.6 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 OAG40735.1 - 0.0084 15.4 0.1 0.015 14.6 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 OAG40735.1 - 0.011 15.0 0.1 0.016 14.5 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 OAG40735.1 - 0.015 14.6 0.1 0.045 13.0 0.1 1.7 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase ApbA PF02558.16 OAG40735.1 - 0.028 14.1 0.2 0.046 13.4 0.2 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Thi4 PF01946.17 OAG40735.1 - 0.046 12.9 0.0 0.078 12.2 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Rossmann-like PF10727.9 OAG40735.1 - 0.058 13.3 0.1 0.14 12.0 0.1 1.7 1 0 0 1 1 1 0 Rossmann-like domain FAD_binding_8 PF08022.12 OAG40738.1 - 1.8e-22 79.5 0.0 3.7e-22 78.5 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 OAG40738.1 - 6.6e-22 78.3 0.0 1.2e-21 77.5 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 OAG40738.1 - 2.3e-19 69.7 11.2 2.3e-19 69.7 11.2 2.3 1 1 1 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.24 OAG40738.1 - 0.03 14.7 0.0 0.064 13.6 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 OAG40738.1 - 0.16 12.6 0.0 3.2 8.4 0.0 2.4 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain SBDS PF01172.18 OAG40739.1 - 1.4e-24 86.0 0.1 1.7e-24 85.7 0.1 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein Mannosyl_trans3 PF11051.8 OAG40740.1 - 3.8e-29 101.9 0.0 9.2e-29 100.6 0.0 1.6 1 1 0 1 1 1 1 Mannosyltransferase putative p450 PF00067.22 OAG40741.1 - 1.7e-80 271.1 0.0 1.9e-80 270.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4131 PF13567.6 OAG40741.1 - 0.064 12.9 0.4 0.86 9.2 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) NIF PF03031.18 OAG40742.1 - 1.7e-53 180.6 0.1 2.6e-53 180.0 0.1 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Abhydrolase_1 PF00561.20 OAG40743.1 - 4.9e-24 85.4 0.0 5.1e-20 72.2 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG40743.1 - 2.4e-15 57.8 0.0 4.4e-15 56.9 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG40743.1 - 5.5e-15 55.3 0.0 9.6e-14 51.2 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 OAG40743.1 - 5.3e-08 32.9 0.1 0.019 14.8 0.0 3.1 1 1 2 3 3 3 3 Phospholipase/Carboxylesterase Ndr PF03096.14 OAG40743.1 - 1.4e-05 23.9 0.0 0.00036 19.3 0.0 2.0 2 0 0 2 2 2 1 Ndr family Peptidase_S9 PF00326.21 OAG40743.1 - 3.4e-05 23.4 0.0 0.0032 17.0 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family DLH PF01738.18 OAG40743.1 - 0.00018 21.1 0.0 0.26 10.8 0.0 2.1 2 0 0 2 2 2 2 Dienelactone hydrolase family BAAT_C PF08840.11 OAG40743.1 - 0.00063 19.7 0.0 0.0016 18.4 0.0 1.6 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_4 PF08386.10 OAG40743.1 - 0.022 14.9 0.0 0.043 13.9 0.0 1.6 1 0 0 1 1 1 0 TAP-like protein Esterase PF00756.20 OAG40743.1 - 0.03 13.9 0.1 0.18 11.5 0.1 2.0 2 0 0 2 2 2 0 Putative esterase DUF915 PF06028.11 OAG40743.1 - 0.097 12.0 0.1 2.8 7.2 0.0 2.6 4 0 0 4 4 4 0 Alpha/beta hydrolase of unknown function (DUF915) EMP70 PF02990.16 OAG40744.1 - 1.2e-187 624.8 0.2 1.4e-187 624.5 0.2 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 Arrestin_N PF00339.29 OAG40745.1 - 3e-05 24.1 0.0 0.0001 22.4 0.0 1.9 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Bul1_C PF04426.12 OAG40745.1 - 0.00055 19.4 0.1 0.0009 18.7 0.1 1.3 1 0 0 1 1 1 1 Bul1 C terminus Bul1_N PF04425.12 OAG40745.1 - 0.00065 18.6 0.1 0.0017 17.2 0.1 1.6 1 1 0 1 1 1 1 Bul1 N terminus Fungal_trans_2 PF11951.8 OAG40750.1 - 1.5e-07 30.6 2.0 3e-07 29.6 2.0 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain IU_nuc_hydro PF01156.19 OAG40750.1 - 0.0012 18.5 0.0 0.0021 17.7 0.0 1.3 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase MPP6 PF10175.9 OAG40751.1 - 0.073 13.6 1.8 0.3 11.6 1.8 2.1 1 0 0 1 1 1 0 M-phase phosphoprotein 6 EBP PF05241.12 OAG40752.1 - 1.4e-59 200.5 10.6 1.7e-59 200.3 10.6 1.1 1 0 0 1 1 1 1 Emopamil binding protein YMF19 PF02326.15 OAG40752.1 - 1.9 9.3 11.8 3.3 8.5 0.2 3.2 3 0 0 3 3 3 0 Plant ATP synthase F0 PhoR PF11808.8 OAG40752.1 - 2.7 8.4 4.7 6.9 7.2 0.0 3.0 2 1 1 3 3 3 0 Phosphate regulon sensor protein PhoR Collagen PF01391.18 OAG40753.1 - 0.00083 19.1 6.8 0.00083 19.1 6.8 2.1 2 1 0 2 2 2 1 Collagen triple helix repeat (20 copies) Sulfotransfer_3 PF13469.6 OAG40753.1 - 0.093 13.1 0.4 0.46 10.8 0.0 2.3 3 1 0 3 3 3 0 Sulfotransferase family AAA_2 PF07724.14 OAG40754.1 - 1.1e-47 162.3 0.0 2.8e-46 157.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 OAG40754.1 - 2.5e-33 114.1 0.7 2.5e-33 114.1 0.7 5.6 5 1 0 6 6 5 1 AAA lid domain AAA PF00004.29 OAG40754.1 - 2.3e-26 92.8 0.0 2.9e-14 53.6 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 OAG40754.1 - 2.3e-24 85.3 0.9 1.1e-23 83.1 0.9 2.3 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 OAG40754.1 - 2.1e-15 56.9 0.2 7.8e-10 38.9 0.0 3.4 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 OAG40754.1 - 9.1e-13 48.7 0.4 4.4e-05 23.8 0.0 4.8 3 1 1 4 4 3 2 AAA domain AAA_16 PF13191.6 OAG40754.1 - 3.5e-11 43.8 13.5 3.5e-06 27.5 0.0 5.9 4 3 0 5 5 5 2 AAA ATPase domain Sigma54_activat PF00158.26 OAG40754.1 - 5.2e-09 36.0 0.0 1.8e-05 24.5 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_14 PF13173.6 OAG40754.1 - 1.8e-06 28.0 0.0 0.099 12.7 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_7 PF12775.7 OAG40754.1 - 3.3e-06 26.7 0.0 0.017 14.7 0.0 2.7 2 0 0 2 2 2 2 P-loop containing dynein motor region IstB_IS21 PF01695.17 OAG40754.1 - 3.8e-06 26.8 0.0 0.1 12.4 0.0 2.9 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_33 PF13671.6 OAG40754.1 - 6e-06 26.5 0.3 0.27 11.4 0.0 3.9 3 0 0 3 3 3 2 AAA domain Mg_chelatase PF01078.21 OAG40754.1 - 1e-05 25.0 0.2 0.19 11.1 0.0 3.6 2 1 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_30 PF13604.6 OAG40754.1 - 3.7e-05 23.5 0.1 0.46 10.2 0.0 3.5 3 0 0 3 3 3 2 AAA domain Clp_N PF02861.20 OAG40754.1 - 6e-05 23.1 10.2 0.00014 21.9 0.2 4.3 4 0 0 4 4 3 1 Clp amino terminal domain, pathogenicity island component ATPase_2 PF01637.18 OAG40754.1 - 9.3e-05 22.4 4.9 0.034 14.1 0.3 4.4 4 1 0 4 4 3 1 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 OAG40754.1 - 9.9e-05 22.7 0.0 0.56 10.6 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AAA_3 PF07726.11 OAG40754.1 - 0.00013 21.9 0.0 0.73 9.7 0.0 3.5 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 OAG40754.1 - 0.00016 21.9 3.8 0.44 10.8 0.0 4.0 3 1 2 5 5 4 2 AAA domain AAA_18 PF13238.6 OAG40754.1 - 0.00018 22.1 7.6 0.07 13.7 0.0 4.4 4 1 0 4 4 3 2 AAA domain RsgA_GTPase PF03193.16 OAG40754.1 - 0.00023 21.1 0.0 0.26 11.2 0.0 3.0 2 0 0 2 2 2 1 RsgA GTPase T2SSE PF00437.20 OAG40754.1 - 0.00026 20.2 0.5 0.0062 15.6 0.0 3.0 2 2 0 2 2 2 1 Type II/IV secretion system protein AAA_19 PF13245.6 OAG40754.1 - 0.00046 20.6 0.4 0.16 12.3 0.1 3.5 3 1 1 4 4 3 1 AAA domain RuvB_N PF05496.12 OAG40754.1 - 0.00051 19.8 1.5 2.6 7.7 0.7 4.3 3 1 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 OAG40754.1 - 0.00052 19.8 0.0 0.53 10.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 OAG40754.1 - 0.00052 20.0 0.0 0.65 10.0 0.0 2.6 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Torsin PF06309.11 OAG40754.1 - 0.0013 18.8 0.0 0.0076 16.4 0.0 2.1 2 0 0 2 2 2 1 Torsin AAA_29 PF13555.6 OAG40754.1 - 0.0015 18.2 0.0 1.3 8.8 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain ABC_tran PF00005.27 OAG40754.1 - 0.0028 18.1 4.2 1 9.9 0.0 3.6 4 0 0 4 4 3 1 ABC transporter ResIII PF04851.15 OAG40754.1 - 0.005 16.9 0.0 2 8.4 0.0 3.6 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Zeta_toxin PF06414.12 OAG40754.1 - 0.0066 15.8 0.0 2.1 7.6 0.0 2.8 2 0 0 2 2 2 1 Zeta toxin Roc PF08477.13 OAG40754.1 - 0.0074 16.5 0.0 2.3 8.4 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase NACHT PF05729.12 OAG40754.1 - 0.01 15.7 0.0 0.9 9.4 0.0 2.8 2 0 0 2 2 2 0 NACHT domain SRP54 PF00448.22 OAG40754.1 - 0.012 15.3 0.0 1.8 8.1 0.0 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain NTPase_1 PF03266.15 OAG40754.1 - 0.021 14.7 0.0 0.49 10.3 0.0 2.8 2 0 0 2 2 2 0 NTPase Rad17 PF03215.15 OAG40754.1 - 0.045 13.7 0.0 9.9 6.0 0.0 2.5 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_25 PF13481.6 OAG40754.1 - 0.075 12.6 0.4 16 5.0 0.0 3.2 2 1 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 OAG40754.1 - 0.082 12.7 0.0 7.5 6.3 0.0 2.9 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_21 PF13304.6 OAG40754.1 - 0.13 12.0 1.8 21 4.8 0.0 3.7 5 0 0 5 5 4 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 OAG40754.1 - 0.38 11.2 0.0 0.38 11.2 0.0 5.1 5 2 1 6 6 2 0 AAA domain V_ATPase_I PF01496.19 OAG40754.1 - 0.43 8.4 6.6 0.079 10.9 2.1 1.8 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Snapin_Pallidin PF14712.6 OAG40754.1 - 2.5 8.6 16.3 1.4 9.4 0.5 3.7 3 1 0 3 3 2 0 Snapin/Pallidin TssO PF17561.2 OAG40754.1 - 2.9 8.0 5.7 4.7 7.3 0.4 3.1 2 0 0 2 2 2 0 Type VI secretion system, TssO T2SSF PF00482.23 OAG40754.1 - 3 7.8 6.1 18 5.3 1.4 3.5 4 0 0 4 4 2 0 Type II secretion system (T2SS), protein F CENP-X PF09415.10 OAG40755.1 - 1.7e-19 69.9 0.0 7e-19 67.9 0.0 2.0 2 0 0 2 2 2 1 CENP-S associating Centromere protein X CBFD_NFYB_HMF PF00808.23 OAG40755.1 - 0.056 13.7 0.1 0.13 12.5 0.0 1.7 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone BUD22 PF09073.10 OAG40755.1 - 0.12 11.7 16.4 0.15 11.3 16.4 1.2 1 0 0 1 1 1 0 BUD22 PPP4R2 PF09184.11 OAG40755.1 - 0.45 10.1 15.0 0.61 9.6 15.0 1.1 1 0 0 1 1 1 0 PPP4R2 Nop14 PF04147.12 OAG40755.1 - 0.64 8.2 16.4 0.78 7.9 16.4 1.1 1 0 0 1 1 1 0 Nop14-like family CDC27 PF09507.10 OAG40755.1 - 0.79 9.0 16.1 1 8.6 16.1 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 TFIIA PF03153.13 OAG40755.1 - 1.3 9.0 17.6 1.7 8.5 17.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 OAG40755.1 - 4.3 6.0 4.4 4.6 5.9 4.4 1.2 1 0 0 1 1 1 0 Presenilin Cu_bind_like PF02298.17 OAG40756.1 - 0.06 13.4 0.0 0.15 12.1 0.0 1.6 1 1 0 1 1 1 0 Plastocyanin-like domain Cupredoxin_1 PF13473.6 OAG40756.1 - 0.11 12.6 0.0 0.55 10.4 0.0 1.9 2 0 0 2 2 2 0 Cupredoxin-like domain Zn_ribbon_recom PF13408.6 OAG40757.1 - 0.032 14.7 0.5 0.071 13.6 0.5 1.5 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain AT_hook PF02178.19 OAG40757.1 - 3.1 8.0 10.8 8.2 6.7 10.8 1.8 1 0 0 1 1 1 0 AT hook motif Mis12 PF05859.12 OAG40758.1 - 1.4e-41 141.7 0.3 3e-41 140.6 0.0 1.6 2 0 0 2 2 2 1 Mis12 protein ZapB PF06005.12 OAG40758.1 - 0.0033 17.8 5.1 0.51 10.8 0.0 3.1 3 0 0 3 3 3 2 Cell division protein ZapB T6SS_VipA PF05591.12 OAG40758.1 - 0.026 14.3 0.7 2.7 7.8 0.3 2.3 2 0 0 2 2 2 0 Type VI secretion system, VipA, VC_A0107 or Hcp2 DUF202 PF02656.15 OAG40759.1 - 0.22 12.0 6.8 7 7.2 6.8 2.8 1 1 0 1 1 1 0 Domain of unknown function (DUF202) NOG1_N PF17835.1 OAG40760.1 - 0.005 16.8 0.0 0.0058 16.6 0.0 1.1 1 0 0 1 1 1 1 NOG1 N-terminal helical domain DUF148 PF02520.17 OAG40760.1 - 0.089 12.9 0.1 0.12 12.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF148 FlxA PF14282.6 OAG40760.1 - 0.09 12.8 0.0 0.12 12.4 0.0 1.1 1 0 0 1 1 1 0 FlxA-like protein Glyco_hydro_43 PF04616.14 OAG40763.1 - 7.7e-18 64.8 0.0 1.3e-17 64.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Cu-oxidase_3 PF07732.15 OAG40764.1 - 1.6e-34 118.5 2.4 6.1e-34 116.6 0.3 2.8 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 OAG40764.1 - 2.4e-28 98.6 2.2 7.6e-22 77.5 0.1 3.4 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 OAG40764.1 - 7e-15 55.5 0.2 7.2e-12 45.7 0.0 3.4 3 1 0 3 3 3 2 Multicopper oxidase Aldedh PF00171.22 OAG40766.1 - 6.2e-143 476.6 0.0 7e-143 476.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family UDG PF03167.19 OAG40767.1 - 5.1e-20 72.0 0.1 1e-19 71.1 0.0 1.5 2 0 0 2 2 2 1 Uracil DNA glycosylase superfamily Het-C PF07217.11 OAG40768.1 - 3.2e-245 815.0 0.0 3.9e-245 814.7 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C DUF1722 PF08349.11 OAG40768.1 - 0.069 13.4 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1722) Ank_2 PF12796.7 OAG40769.1 - 2.2e-22 79.4 10.9 2.3e-06 28.1 0.0 8.6 5 2 3 8 8 8 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAG40769.1 - 1.5e-10 41.4 15.2 0.14 12.7 0.0 10.1 12 0 0 12 12 12 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG40769.1 - 1e-08 34.7 9.1 2.2 9.1 0.1 12.3 12 0 0 12 12 12 1 Ankyrin repeat IBR PF01485.21 OAG40769.1 - 0.00013 22.1 21.1 0.00067 19.8 2.5 3.4 4 0 0 4 4 4 2 IBR domain, a half RING-finger domain Ank_5 PF13857.6 OAG40769.1 - 0.011 16.1 1.0 2.3 8.7 0.0 5.1 4 0 0 4 4 4 0 Ankyrin repeats (many copies) DUF2811 PF10929.8 OAG40769.1 - 0.43 10.9 2.4 34 4.8 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF2811) Cupin_2 PF07883.11 OAG40770.1 - 1.7e-05 24.5 1.5 3e-05 23.6 1.0 1.7 2 0 0 2 2 2 1 Cupin domain DUF1691 PF07950.11 OAG40771.1 - 0.0038 17.9 0.1 0.0095 16.7 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1691) FA_desaturase PF00487.24 OAG40771.1 - 0.0076 16.1 5.4 0.012 15.5 5.4 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Tetraspanin PF00335.20 OAG40771.1 - 5.6 6.6 5.8 16 5.1 5.8 1.7 1 1 0 1 1 1 0 Tetraspanin family 4HBT_3 PF13622.6 OAG40772.1 - 7.7e-80 268.7 0.2 9.6e-80 268.4 0.2 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 OAG40772.1 - 2.2e-24 85.8 0.0 3.4e-11 43.1 0.0 4.6 4 1 0 4 4 4 3 Acyl-CoA thioesterase DUF3290 PF11694.8 OAG40772.1 - 0.041 13.9 0.0 0.068 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3290) Prefoldin_2 PF01920.20 OAG40773.1 - 7.4e-23 80.5 2.4 1e-22 80.1 2.4 1.2 1 0 0 1 1 1 1 Prefoldin subunit Type2_restr_D3 PF16902.5 OAG40773.1 - 0.0079 16.1 0.6 0.017 15.0 0.1 1.8 2 0 0 2 2 2 1 Type-2 restriction enzyme D3 domain Prefoldin PF02996.17 OAG40773.1 - 0.018 15.0 0.4 0.018 15.0 0.4 2.3 1 1 1 2 2 2 0 Prefoldin subunit ADIP PF11559.8 OAG40773.1 - 0.035 14.2 11.5 0.41 10.7 7.0 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding bZIP_1 PF00170.21 OAG40773.1 - 0.058 13.5 0.3 0.058 13.5 0.3 2.5 2 1 0 2 2 2 0 bZIP transcription factor End3 PF12761.7 OAG40773.1 - 0.068 13.3 9.5 0.3 11.3 9.5 1.7 1 1 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 DUF1664 PF07889.12 OAG40773.1 - 0.13 12.3 2.0 0.98 9.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Med30 PF11315.8 OAG40773.1 - 0.15 12.3 2.3 0.3 11.3 2.3 1.5 1 1 0 1 1 1 0 Mediator complex subunit 30 FlaC_arch PF05377.11 OAG40773.1 - 0.2 12.1 2.4 0.4 11.1 0.0 2.4 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Seryl_tRNA_N PF02403.22 OAG40773.1 - 0.22 11.8 7.3 6.1 7.1 0.1 2.2 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Spore_III_AB PF09548.10 OAG40773.1 - 1.2 9.2 5.3 11 6.2 2.8 2.3 2 1 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) DivIC PF04977.15 OAG40773.1 - 1.3 8.9 6.9 6 6.7 0.1 2.4 2 1 0 2 2 2 0 Septum formation initiator UPF0242 PF06785.11 OAG40773.1 - 3 7.9 9.4 3.9 7.5 9.4 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus CENP-H PF05837.12 OAG40773.1 - 4.7 7.7 10.8 23 5.5 0.1 2.1 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Rx_N PF18052.1 OAG40773.1 - 4.8 7.5 8.5 6.6 7.1 1.2 2.5 3 0 0 3 3 3 0 Rx N-terminal domain Isochorismatase PF00857.20 OAG40774.1 - 2.2e-14 54.0 0.0 3.5e-14 53.4 0.0 1.3 1 1 0 1 1 1 1 Isochorismatase family ATG27 PF09451.10 OAG40775.1 - 5e-97 324.9 0.0 5.9e-97 324.7 0.0 1.0 1 0 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.18 OAG40775.1 - 0.00057 20.0 0.2 0.046 13.8 0.0 2.5 3 0 0 3 3 3 1 Cation-independent mannose-6-phosphate receptor repeat DUF4637 PF15470.6 OAG40775.1 - 0.13 11.9 2.2 0.26 11.0 2.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4637) CENP-B_dimeris PF09026.10 OAG40775.1 - 0.27 11.7 4.3 0.53 10.7 4.3 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Asp-B-Hydro_N PF05279.11 OAG40775.1 - 0.32 11.0 7.1 0.3 11.1 0.7 2.1 2 0 0 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region FAM176 PF14851.6 OAG40775.1 - 0.54 9.9 5.4 0.26 11.0 2.9 1.7 2 0 0 2 2 2 0 FAM176 family Peptidase_S49_N PF08496.10 OAG40775.1 - 1.7 8.7 3.4 2.7 8.0 3.4 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Acetyltransf_1 PF00583.25 OAG40776.1 - 8.3e-06 26.0 0.0 1.5e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OAG40776.1 - 8.6e-06 26.1 0.0 2.5e-05 24.6 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OAG40776.1 - 2.5e-05 24.2 0.0 4.1e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 OAG40776.1 - 0.00093 19.3 0.0 0.0016 18.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 OAG40776.1 - 0.043 13.5 0.0 0.068 12.9 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAG40776.1 - 0.18 11.8 0.0 0.62 10.1 0.0 1.9 2 0 0 2 2 2 0 FR47-like protein GMC_oxred_N PF00732.19 OAG40777.1 - 1.5e-56 192.0 0.0 2e-56 191.6 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAG40777.1 - 3.2e-32 112.0 0.2 4.9e-32 111.4 0.2 1.3 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 OAG40777.1 - 1.4e-07 31.6 0.0 4.5e-07 30.0 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAG40777.1 - 9.7e-07 28.7 2.0 1.4e-05 24.9 2.0 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 OAG40777.1 - 1.5e-06 27.6 1.8 3.5e-06 26.3 0.2 2.2 2 1 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 OAG40777.1 - 9.5e-06 24.9 0.7 0.0095 15.0 0.1 2.3 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 OAG40777.1 - 0.00019 20.7 0.1 0.0015 17.8 0.1 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG40777.1 - 0.036 13.3 0.3 4.3 6.5 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OAG40777.1 - 0.088 11.9 0.3 0.39 9.7 0.1 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A Dimerisation PF08100.11 OAG40777.1 - 0.11 12.5 0.0 0.52 10.4 0.0 2.2 2 0 0 2 2 2 0 Dimerisation domain Pyr_redox PF00070.27 OAG40777.1 - 0.14 12.8 0.1 0.58 10.7 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.16 OAG40778.1 - 1.5e-28 99.7 23.5 2.3e-28 99.2 23.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Peptidase_U4 PF03419.13 OAG40778.1 - 0.0014 18.0 5.6 0.0014 18.0 5.6 2.4 2 1 0 2 2 2 1 Sporulation factor SpoIIGA DUF1772 PF08592.11 OAG40778.1 - 2.5 8.4 11.8 11 6.3 0.0 3.8 3 1 1 4 4 4 0 Domain of unknown function (DUF1772) Thaumatin PF00314.17 OAG40780.1 - 3.4e-66 222.9 2.7 5.1e-66 222.4 2.7 1.3 1 0 0 1 1 1 1 Thaumatin family Glyco_hydro_64 PF16483.5 OAG40780.1 - 0.025 13.9 0.1 0.43 9.8 0.0 2.2 2 0 0 2 2 2 0 Beta-1,3-glucanase Aldedh PF00171.22 OAG40781.1 - 5.2e-116 387.9 0.9 6.4e-116 387.6 0.9 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF3455 PF11937.8 OAG40783.1 - 6.6e-43 146.8 0.2 1.4e-42 145.8 0.1 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3455) DUF2990 PF11693.8 OAG40783.1 - 5.3e-12 45.7 0.6 1.5e-11 44.2 0.6 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2990) CASP_C PF08172.12 OAG40784.1 - 1.3e-88 296.6 0.0 1.3e-88 296.6 0.0 4.1 3 1 1 4 4 4 1 CASP C terminal KLRAQ PF10205.9 OAG40784.1 - 0.021 15.1 1.5 0.021 15.1 1.5 5.7 4 1 3 7 7 7 0 Predicted coiled-coil domain-containing protein NAD_binding_1 PF00175.21 OAG40784.1 - 2.5 8.8 4.4 5.5 7.7 0.0 3.2 3 0 0 3 3 3 0 Oxidoreductase NAD-binding domain Calcipressin PF04847.12 OAG40784.1 - 6 6.6 9.0 11 5.7 3.5 3.0 2 1 0 2 2 2 0 Calcipressin Vps39_2 PF10367.9 OAG40785.1 - 1.9e-06 28.3 0.0 4.8e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Transp_cyt_pur PF02133.15 OAG40786.1 - 1.2e-90 304.4 35.6 1.5e-90 304.1 35.6 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Aldo_ket_red PF00248.21 OAG40787.1 - 9.1e-46 156.4 0.0 4.2e-44 150.9 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Fungal_trans PF04082.18 OAG40788.1 - 1.8e-21 76.4 1.1 2.8e-21 75.7 1.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF1989 PF09347.10 OAG40789.1 - 4.1e-52 176.2 0.0 7.2e-52 175.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) Polysacc_deac_1 PF01522.21 OAG40789.1 - 4.2e-17 62.2 0.0 8e-17 61.3 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 OAG40789.1 - 1.9e-07 30.9 0.1 3.4e-07 30.1 0.1 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) DUF2194 PF09960.9 OAG40789.1 - 0.049 12.0 0.0 0.072 11.4 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2194) BTB PF00651.31 OAG40790.1 - 5.2e-19 68.5 0.1 1.6e-18 66.9 0.1 1.8 1 0 0 1 1 1 1 BTB/POZ domain Cep57_CLD_2 PF14197.6 OAG40791.1 - 0.00059 19.9 6.6 0.00059 19.9 6.6 8.4 4 4 3 7 7 7 2 Centrosome localisation domain of PPC89 CENP-F_leu_zip PF10473.9 OAG40791.1 - 0.02 15.0 101.7 0.018 15.0 10.7 5.8 1 1 3 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fez1 PF06818.15 OAG40791.1 - 5.8 7.3 82.7 4.3 7.7 4.1 5.4 1 1 3 4 4 4 0 Fez1 DUF3153 PF11353.8 OAG40791.1 - 7.4 6.1 6.7 4.5 6.8 1.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3153) Isochorismatase PF00857.20 OAG40793.1 - 1.3e-28 100.4 0.0 3.2e-28 99.1 0.0 1.7 2 0 0 2 2 2 1 Isochorismatase family TauD PF02668.16 OAG40797.1 - 4.7e-57 193.8 0.2 5.5e-57 193.6 0.2 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF1479 PF07350.12 OAG40797.1 - 0.055 12.2 0.1 0.092 11.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1479) TPR_11 PF13414.6 OAG40797.1 - 0.087 12.5 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 TPR repeat P16-Arc PF04699.14 OAG40798.1 - 4.3e-45 153.8 0.0 4.9e-45 153.6 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Dynactin_p62 PF05502.13 OAG40799.1 - 1.9e-130 435.9 0.0 2.5e-130 435.5 0.0 1.0 1 0 0 1 1 1 1 Dynactin p62 family Methyltransf_23 PF13489.6 OAG40800.1 - 1e-11 44.9 0.0 1.5e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG40800.1 - 2.8e-10 40.7 0.0 6.3e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG40800.1 - 4.1e-07 30.6 0.0 2.2e-06 28.3 0.0 2.1 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG40800.1 - 4.9e-06 27.2 0.0 9.6e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG40800.1 - 0.00011 22.0 0.0 0.00039 20.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAG40800.1 - 0.031 13.6 0.0 0.05 12.9 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Ribosomal_S7e PF01251.18 OAG40801.1 - 1.7e-78 262.6 0.1 2e-78 262.4 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e ADH_zinc_N PF00107.26 OAG40802.1 - 1.7e-22 79.8 0.1 2.8e-22 79.1 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAG40802.1 - 1.1e-14 55.6 0.0 3e-14 54.2 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG40802.1 - 1.1e-08 34.9 0.0 2.9e-08 33.5 0.0 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.18 OAG40802.1 - 0.0062 16.8 0.0 0.012 15.9 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain AlaDh_PNT_C PF01262.21 OAG40802.1 - 0.011 15.1 0.6 0.025 13.9 0.2 1.6 1 1 1 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain GST_N_3 PF13417.6 OAG40803.1 - 9.6e-10 38.7 0.1 3.3e-09 37.0 0.1 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OAG40803.1 - 4.2e-07 30.2 0.1 7.5e-07 29.4 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAG40803.1 - 5.4e-06 26.3 0.0 9.7e-06 25.5 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OAG40803.1 - 1.7e-05 24.9 0.0 3.3e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OAG40803.1 - 0.00014 22.0 0.0 0.00022 21.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 OAG40803.1 - 0.00055 20.5 0.0 0.001 19.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin2_C PF04399.13 OAG40803.1 - 0.00071 19.4 0.0 0.0011 18.7 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin 2, C terminal domain GST_N PF02798.20 OAG40803.1 - 0.0089 16.4 0.1 0.034 14.5 0.0 2.0 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain zf-RING_2 PF13639.6 OAG40806.1 - 2.5e-12 46.9 5.3 3.9e-12 46.3 5.3 1.3 1 0 0 1 1 1 1 Ring finger domain PA PF02225.22 OAG40806.1 - 1.1e-09 38.1 0.2 4.5e-09 36.2 0.0 2.1 2 0 0 2 2 2 1 PA domain zf-RING_11 PF17123.5 OAG40806.1 - 6.9e-09 35.3 2.9 6.9e-09 35.3 2.9 1.9 2 0 0 2 2 2 1 RING-like zinc finger zf-rbx1 PF12678.7 OAG40806.1 - 2.4e-08 34.2 2.6 4.7e-08 33.2 2.6 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 OAG40806.1 - 4.6e-08 32.8 3.3 7.3e-08 32.2 3.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OAG40806.1 - 5.1e-08 32.6 4.3 8.2e-08 32.0 4.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAG40806.1 - 1.3e-07 31.4 2.2 2.1e-07 30.8 2.2 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 OAG40806.1 - 2.1e-05 24.3 2.8 3.2e-05 23.7 2.8 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAG40806.1 - 6.6e-05 22.8 2.3 0.00011 22.2 0.5 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 OAG40806.1 - 0.0033 17.5 0.7 0.0067 16.4 0.7 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 OAG40806.1 - 0.0035 17.2 2.9 0.0059 16.4 2.9 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 OAG40806.1 - 0.089 13.0 2.9 0.22 11.7 2.9 1.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 OAG40806.1 - 0.15 12.2 2.4 0.44 10.8 2.4 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 OAG40806.1 - 0.26 11.0 2.8 0.46 10.1 2.8 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 OAG40806.1 - 0.27 11.1 3.0 0.49 10.2 3.0 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.29 OAG40806.1 - 0.41 10.6 2.8 0.77 9.7 2.8 1.5 1 0 0 1 1 1 0 PHD-finger zf-RING-like PF08746.11 OAG40806.1 - 1.6 9.1 3.0 2.8 8.3 3.0 1.4 1 0 0 1 1 1 0 RING-like domain RINGv PF12906.7 OAG40806.1 - 1.9 8.7 3.8 3.6 7.8 3.8 1.5 1 0 0 1 1 1 0 RING-variant domain MIP PF00230.20 OAG40807.1 - 1.4e-50 172.2 11.2 1.9e-50 171.7 11.2 1.1 1 0 0 1 1 1 1 Major intrinsic protein PRP21_like_P PF12230.8 OAG40808.1 - 1.4e-52 178.8 5.9 9.9e-28 97.5 4.0 2.3 2 0 0 2 2 2 2 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.20 OAG40808.1 - 1.1e-37 127.8 1.3 1.8e-20 72.6 0.0 2.3 2 0 0 2 2 2 2 Surp module zf_UBZ PF18439.1 OAG40808.1 - 0.0042 16.7 0.0 0.0097 15.5 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger PMT PF02366.18 OAG40809.1 - 4.5e-79 265.5 16.1 7.9e-79 264.7 16.1 1.4 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 OAG40809.1 - 2.9e-68 229.4 13.4 2.9e-68 229.4 13.4 2.4 2 0 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 OAG40809.1 - 3.7e-46 157.3 0.2 6.3e-46 156.6 0.2 1.3 1 0 0 1 1 1 1 MIR domain EB1 PF03271.17 OAG40810.1 - 4.5e-17 62.0 0.3 9.1e-17 61.0 0.3 1.6 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.31 OAG40810.1 - 0.00015 21.9 0.4 0.00059 20.0 0.1 2.0 2 0 0 2 2 2 1 Calponin homology (CH) domain Syja_N PF02383.18 OAG40810.1 - 0.063 12.6 0.0 0.063 12.6 0.0 1.1 1 0 0 1 1 1 0 SacI homology domain Whi5 PF08528.11 OAG40813.1 - 3.3e-10 39.4 0.7 6.6e-10 38.4 0.7 1.6 1 0 0 1 1 1 1 Whi5 like DUF4239 PF14023.6 OAG40813.1 - 0.36 10.5 4.1 0.28 10.9 1.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4239) Peptidase_C15 PF01470.17 OAG40816.1 - 8.5e-12 45.7 0.0 1.2e-08 35.4 0.0 3.2 2 1 0 2 2 2 2 Pyroglutamyl peptidase DUF5423 PF17461.2 OAG40816.1 - 1.4 7.7 5.6 2.3 7.0 5.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5423) Mad3_BUB1_I PF08311.12 OAG40817.1 - 1.2e-43 148.0 0.1 2e-43 147.3 0.1 1.4 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Mad3_BUB1_II PF08171.11 OAG40817.1 - 1e-15 57.6 0.0 4.2e-14 52.5 0.0 2.6 2 0 0 2 2 2 1 Mad3/BUB1 homology region 2 Pkinase PF00069.25 OAG40817.1 - 1.6e-07 31.0 0.0 1.1e-06 28.2 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG40817.1 - 0.0021 17.4 0.0 0.012 14.9 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Mad3_BUB1_I_2 PF17014.5 OAG40817.1 - 0.057 13.5 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Putative Mad3/BUB1 like region 1 protein Ribosomal_S4e PF00900.20 OAG40819.1 - 2.4e-37 126.7 0.3 6.5e-37 125.3 0.2 1.8 2 0 0 2 2 2 1 Ribosomal family S4e 40S_S4_C PF16121.5 OAG40819.1 - 4.7e-24 83.8 0.1 7.9e-24 83.0 0.1 1.4 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 OAG40819.1 - 6.3e-17 61.4 6.7 1.2e-16 60.6 6.7 1.5 1 0 0 1 1 1 1 RS4NT (NUC023) domain KOW PF00467.29 OAG40819.1 - 0.00015 21.5 2.9 0.00015 21.5 2.9 2.5 2 0 0 2 2 2 1 KOW motif S4 PF01479.25 OAG40819.1 - 0.02 14.6 0.0 0.041 13.6 0.0 1.6 1 0 0 1 1 1 0 S4 domain Methyltransf_23 PF13489.6 OAG40820.1 - 2.3e-26 92.6 0.0 3.4e-26 92.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG40820.1 - 6.1e-11 42.9 0.0 2.2e-10 41.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG40820.1 - 3.2e-09 36.7 0.0 0.00038 20.3 0.0 2.1 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 OAG40820.1 - 1.7e-08 35.1 0.0 2.3e-07 31.5 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG40820.1 - 4.3e-07 30.5 0.0 1e-06 29.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OAG40820.1 - 0.0018 17.9 0.0 0.016 14.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase small domain CMAS PF02353.20 OAG40820.1 - 0.0055 16.0 0.0 0.15 11.3 0.0 2.7 3 0 0 3 3 3 1 Mycolic acid cyclopropane synthetase FtsJ PF01728.19 OAG40820.1 - 0.03 14.5 0.0 0.065 13.3 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_16 PF10294.9 OAG40820.1 - 0.069 12.9 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_4 PF02390.17 OAG40820.1 - 0.1 12.0 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase SecD_SecF PF02355.16 OAG40820.1 - 0.15 11.4 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein export membrane protein p450 PF00067.22 OAG40821.1 - 3.6e-65 220.5 0.1 4.7e-65 220.1 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 FRB_dom PF08771.11 OAG40821.1 - 0.1 13.0 0.4 42 4.6 0.0 3.3 4 0 0 4 4 4 0 FKBP12-rapamycin binding domain Mannosyl_trans2 PF04188.13 OAG40822.1 - 2.8e-49 168.6 12.9 3.9e-49 168.2 12.9 1.1 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V) Velvet PF11754.8 OAG40824.1 - 1.2e-19 71.3 3.3 3.5e-14 53.3 0.7 3.6 2 2 1 3 3 3 2 Velvet factor GFA PF04828.14 OAG40825.1 - 2.9e-21 75.6 3.4 4.5e-10 39.7 0.3 3.6 2 2 0 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme DUF3104 PF11302.8 OAG40825.1 - 0.032 14.0 0.1 0.077 12.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3104) zf-CSL PF05207.13 OAG40825.1 - 0.075 12.8 0.2 0.075 12.8 0.2 3.6 4 0 0 4 4 4 0 CSL zinc finger NOB1_Zn_bind PF08772.11 OAG40825.1 - 0.076 13.2 1.5 8.8 6.6 0.0 2.6 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like zf-NADH-PPase PF09297.11 OAG40825.1 - 3.3 7.5 16.7 1.9 8.2 0.2 3.8 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain Ribosomal_S27 PF01599.19 OAG40825.1 - 3.9 7.7 8.0 17 5.7 1.5 2.6 2 0 0 2 2 2 0 Ribosomal protein S27a RNA_POL_M_15KD PF02150.16 OAG40825.1 - 4.1 7.4 0.0 4.1 7.4 0.0 4.0 4 0 0 4 4 4 0 RNA polymerases M/15 Kd subunit Sugar_tr PF00083.24 OAG40826.1 - 3.1e-80 270.2 21.4 3.6e-80 270.0 21.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG40826.1 - 1.4e-30 106.5 47.1 1.7e-29 102.9 24.2 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily PhyH PF05721.13 OAG40827.1 - 0.0011 19.3 0.0 0.0036 17.6 0.0 1.7 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Glyco_hydro_1 PF00232.18 OAG40827.1 - 0.2 10.0 0.0 0.29 9.5 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 1 DUF2407_C PF13373.6 OAG40828.1 - 7.3e-43 146.1 0.0 7.3e-43 146.1 0.0 1.6 2 0 0 2 2 2 1 DUF2407 C-terminal domain DUF2407 PF10302.9 OAG40828.1 - 7.7e-29 100.3 0.3 2.5e-28 98.7 0.0 1.9 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.23 OAG40828.1 - 0.0035 17.1 0.0 0.006 16.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family V-SNARE PF05008.15 OAG40829.1 - 5.3e-23 81.2 4.3 5.3e-23 81.2 4.3 2.0 2 1 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 OAG40829.1 - 8.6e-19 67.6 4.8 8.6e-19 67.6 4.8 2.7 4 0 0 4 4 4 1 Snare region anchored in the vesicle membrane C-terminus DUF1542 PF07564.11 OAG40829.1 - 0.048 13.8 1.6 0.13 12.4 1.6 1.7 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1542) DDE_Tnp_1 PF01609.21 OAG40829.1 - 0.091 12.4 0.5 0.12 12.0 0.5 1.3 1 1 0 1 1 1 0 Transposase DDE domain Sec20 PF03908.13 OAG40829.1 - 0.19 11.7 3.2 0.44 10.5 0.3 2.3 2 0 0 2 2 2 0 Sec20 ARGLU PF15346.6 OAG40829.1 - 0.21 11.5 7.2 0.19 11.6 6.1 1.5 1 1 0 1 1 1 0 Arginine and glutamate-rich 1 Prominin PF05478.11 OAG40829.1 - 0.89 7.4 3.9 1.4 6.8 1.6 1.8 1 1 1 2 2 2 0 Prominin zf-C4H2 PF10146.9 OAG40829.1 - 0.91 9.8 7.5 2.8 8.2 7.4 1.9 1 1 0 1 1 1 0 Zinc finger-containing protein DUF4407 PF14362.6 OAG40829.1 - 1 8.6 8.1 1.3 8.3 8.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3883 PF13020.6 OAG40830.1 - 0.0054 16.7 0.0 0.013 15.5 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3883) HATPase_c_3 PF13589.6 OAG40830.1 - 0.014 15.2 0.0 0.032 14.0 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Amino_oxidase PF01593.24 OAG40831.1 - 7.6e-12 45.2 0.0 6.1e-11 42.3 0.0 2.3 2 1 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OAG40831.1 - 1.1e-09 38.4 0.0 1.9e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 OAG40831.1 - 2.8e-08 33.9 0.0 0.002 18.1 0.0 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding DAO PF01266.24 OAG40831.1 - 0.00077 19.1 0.2 0.061 12.9 0.2 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG40831.1 - 0.033 13.4 0.0 0.63 9.2 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ETF PF01012.21 OAG40831.1 - 0.048 13.6 0.0 1.7 8.5 0.0 2.2 2 0 0 2 2 2 0 Electron transfer flavoprotein domain ATP_bind_3 PF01171.20 OAG40832.1 - 1.9e-19 70.1 0.0 4.2e-19 69.0 0.0 1.6 2 0 0 2 2 2 1 PP-loop family zn-ribbon_14 PF16503.5 OAG40832.1 - 2.7e-17 61.9 14.7 7.9e-17 60.5 3.4 4.0 4 0 0 4 4 4 2 Zinc-ribbon RecR PF02132.15 OAG40832.1 - 0.0018 17.8 0.8 0.0018 17.8 0.8 3.5 4 0 0 4 4 4 1 RecR protein tRNA_Me_trans PF03054.16 OAG40832.1 - 0.018 13.9 0.0 0.031 13.1 0.0 1.4 1 0 0 1 1 1 0 tRNA methyl transferase zf-UBR PF02207.20 OAG40832.1 - 0.19 11.9 4.1 1.6 9.0 0.1 2.7 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) AAA PF00004.29 OAG40833.1 - 4.1e-37 127.6 0.0 1e-36 126.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OAG40833.1 - 6.1e-10 38.8 0.0 1.5e-09 37.5 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 OAG40833.1 - 0.0002 21.8 0.6 0.015 15.7 0.1 3.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 OAG40833.1 - 0.00032 20.9 0.0 0.0083 16.3 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 OAG40833.1 - 0.00092 19.5 2.2 0.16 12.2 0.1 3.6 3 1 1 4 4 4 1 AAA domain RuvB_N PF05496.12 OAG40833.1 - 0.0034 17.1 0.0 0.0066 16.2 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 OAG40833.1 - 0.0077 16.4 0.0 0.025 14.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) ox_reductase_C PF08635.10 OAG40833.1 - 0.018 14.7 0.1 0.037 13.7 0.1 1.4 1 0 0 1 1 1 0 Putative oxidoreductase C terminal domain Rad17 PF03215.15 OAG40833.1 - 0.042 13.8 0.0 0.082 12.8 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_14 PF13173.6 OAG40833.1 - 0.054 13.5 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 OAG40833.1 - 0.063 13.3 0.1 0.18 11.8 0.1 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 OAG40833.1 - 0.063 13.8 0.0 0.24 12.0 0.0 2.0 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 OAG40833.1 - 0.075 12.4 0.0 0.18 11.2 0.0 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 OAG40833.1 - 0.082 13.3 0.0 0.2 12.1 0.0 1.7 1 0 0 1 1 1 0 RNA helicase IstB_IS21 PF01695.17 OAG40833.1 - 0.09 12.5 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.13 OAG40833.1 - 0.17 11.1 0.0 0.31 10.2 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_18 PF13238.6 OAG40834.1 - 0.00066 20.2 0.0 0.0023 18.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain PRK PF00485.18 OAG40834.1 - 0.0012 18.6 0.0 0.002 17.9 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_16 PF13191.6 OAG40834.1 - 0.011 16.1 0.0 0.021 15.2 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain CPT PF07931.12 OAG40834.1 - 0.049 13.5 0.2 0.12 12.2 0.0 1.7 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_28 PF13521.6 OAG40834.1 - 0.071 13.3 0.4 0.18 12.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 OAG40834.1 - 0.081 12.6 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain MobB PF03205.14 OAG40834.1 - 0.1 12.5 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B LIM_bind PF01803.16 OAG40835.1 - 7e-44 150.2 0.2 7e-44 150.2 0.2 4.7 3 2 1 4 4 4 1 LIM-domain binding protein TIP49 PF06068.13 OAG40836.1 - 2e-165 550.2 0.0 2.5e-165 549.9 0.0 1.0 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 OAG40836.1 - 2.2e-24 85.3 0.1 8.7e-24 83.4 0.0 2.0 2 0 0 2 2 2 1 TIP49 AAA-lid domain AAA PF00004.29 OAG40836.1 - 6e-11 42.9 0.1 4.2e-07 30.5 0.1 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 OAG40836.1 - 6.8e-10 38.9 0.1 1e-06 28.6 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 OAG40836.1 - 5.2e-05 23.5 0.1 0.33 11.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 OAG40836.1 - 8.3e-05 23.0 0.1 0.00067 20.1 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 OAG40836.1 - 0.00021 21.6 0.7 0.06 13.7 0.2 2.3 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 OAG40836.1 - 0.00044 20.5 0.1 0.002 18.4 0.1 2.0 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 OAG40836.1 - 0.0012 18.8 0.1 0.19 11.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 OAG40836.1 - 0.0013 18.5 0.1 0.78 9.4 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain Zeta_toxin PF06414.12 OAG40836.1 - 0.0054 16.0 0.2 0.013 14.8 0.2 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_25 PF13481.6 OAG40836.1 - 0.019 14.5 0.0 0.039 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 OAG40836.1 - 0.022 14.2 0.1 0.68 9.3 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ATPase PF06745.13 OAG40836.1 - 0.046 13.1 0.7 0.12 11.7 0.1 1.8 2 0 0 2 2 2 0 KaiC DnaB_C PF03796.15 OAG40836.1 - 0.051 12.9 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_14 PF13173.6 OAG40836.1 - 0.059 13.4 0.0 1.1 9.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 OAG40836.1 - 0.061 13.0 0.1 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.6 OAG40836.1 - 0.069 13.7 0.0 0.21 12.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 OAG40836.1 - 0.069 12.9 0.1 0.7 9.6 0.1 2.3 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 OAG40836.1 - 0.076 12.2 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 OAG40836.1 - 0.12 11.9 0.3 0.42 10.1 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region Ribosomal_L28 PF00830.19 OAG40837.1 - 5.4e-12 45.7 0.4 1.5e-11 44.3 0.4 1.7 1 0 0 1 1 1 1 Ribosomal L28 family DSBA PF01323.20 OAG40838.1 - 6.9e-30 104.3 0.0 8.9e-30 103.9 0.0 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain SNF2_N PF00176.23 OAG40839.1 - 1.6e-43 148.8 0.0 1.4e-41 142.4 0.0 2.2 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OAG40839.1 - 1.2e-07 32.1 0.0 2.4e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG40839.1 - 0.00075 19.5 0.0 0.8 9.7 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Ald_Xan_dh_C2 PF02738.18 OAG40840.1 - 4.8e-207 688.8 0.1 6.9e-207 688.2 0.1 1.2 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.21 OAG40840.1 - 6.9e-46 156.1 0.0 1.4e-45 155.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.17 OAG40840.1 - 2.9e-32 110.9 0.1 5.1e-31 106.9 0.0 3.0 3 0 0 3 3 3 1 CO dehydrogenase flavoprotein C-terminal domain Fer2_2 PF01799.20 OAG40840.1 - 7.5e-29 99.6 0.0 1.7e-28 98.5 0.0 1.6 1 0 0 1 1 1 1 [2Fe-2S] binding domain Ald_Xan_dh_C PF01315.22 OAG40840.1 - 2.4e-27 95.4 0.0 6.3e-27 94.1 0.0 1.8 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2 PF00111.27 OAG40840.1 - 2.5e-08 33.7 1.6 3.2e-08 33.4 0.1 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain FAM199X PF15814.5 OAG40841.1 - 0.012 14.7 8.3 0.024 13.7 8.3 1.5 1 0 0 1 1 1 0 Protein family FAM199X Miga PF10265.9 OAG40841.1 - 6.5 5.6 7.2 22 3.8 7.7 1.6 2 0 0 2 2 2 0 Mitoguardin KH_1 PF00013.29 OAG40842.1 - 1e-31 108.5 6.8 3.5e-15 55.6 0.1 3.0 3 0 0 3 3 3 2 KH domain KH_2 PF07650.17 OAG40842.1 - 6.5e-06 25.9 2.2 0.069 13.0 0.3 2.5 2 0 0 2 2 2 2 KH domain KH_4 PF13083.6 OAG40842.1 - 2e-05 24.4 3.8 0.014 15.2 0.2 2.5 2 0 0 2 2 2 2 KH domain KH_5 PF13184.6 OAG40842.1 - 1.4 9.0 5.9 21 5.3 0.1 2.9 2 1 0 2 2 2 0 NusA-like KH domain H-kinase_dim PF02895.14 OAG40844.1 - 0.14 12.6 0.1 9.8 6.7 0.0 2.9 2 0 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain Glyco_hydro_130 PF04041.13 OAG40845.1 - 2.9e-44 151.3 0.0 6.1e-44 150.3 0.0 1.4 1 1 0 1 1 1 1 beta-1,4-mannooligosaccharide phosphorylase Glyco_hydro_43 PF04616.14 OAG40845.1 - 5.8e-08 32.4 0.4 0.00036 19.9 0.1 3.8 4 0 0 4 4 4 3 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.20 OAG40845.1 - 4.7e-07 29.7 0.1 0.00024 20.8 0.0 2.6 3 0 0 3 3 3 2 Glycosyl hydrolases family 32 N-terminal domain DNA_pol_E_B PF04042.16 OAG40845.1 - 7.9e-07 28.6 0.4 1.2e-06 28.0 0.4 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Nup96 PF12110.8 OAG40846.1 - 3.7e-57 193.7 3.1 5.1e-57 193.2 3.1 1.2 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.14 OAG40846.1 - 2.3e-50 170.6 0.0 4.4e-50 169.7 0.0 1.5 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.6 OAG40846.1 - 2.8e-09 37.7 275.4 6e-07 30.2 30.9 9.2 3 2 3 7 7 7 4 Nucleoporin FG repeat region GET2 PF08690.10 OAG40847.1 - 2.5e-13 50.4 1.9 1.7e-12 47.6 0.2 2.5 1 1 1 2 2 2 1 GET complex subunit GET2 Tom5 PF10642.9 OAG40847.1 - 0.78 9.8 3.8 9.8 6.3 0.5 2.9 2 0 0 2 2 2 0 Mitochondrial import receptor subunit or translocase AMP-binding PF00501.28 OAG40848.1 - 5.4e-87 292.1 0.2 7.3e-87 291.7 0.2 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG40848.1 - 2.1e-27 95.9 0.3 6.1e-26 91.2 0.2 2.6 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 OAG40848.1 - 1.8e-20 72.6 1.2 4.1e-20 71.4 1.2 1.7 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus EF-hand_7 PF13499.6 OAG40849.1 - 1.2e-15 57.7 0.8 1.5e-08 34.9 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 OAG40849.1 - 3e-14 51.4 0.2 6.1e-06 25.4 0.0 3.3 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 OAG40849.1 - 1.2e-12 46.6 0.2 1.5e-05 24.6 0.1 3.4 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.6 OAG40849.1 - 1.4e-09 37.6 0.8 2.2e-06 27.4 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_4 PF12763.7 OAG40849.1 - 0.00071 19.5 0.0 0.0028 17.6 0.0 1.8 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 OAG40849.1 - 0.0022 18.3 0.3 0.005 17.1 0.0 1.7 2 0 0 2 2 2 1 EF-hand domain IMS PF00817.20 OAG40850.1 - 3e-37 127.9 0.0 5.9e-37 127.0 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 OAG40850.1 - 1.7e-16 61.0 0.1 3.5e-15 56.7 0.0 2.3 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 OAG40850.1 - 0.00028 21.0 1.7 0.0034 17.6 0.0 2.9 3 0 0 3 3 3 1 IMS family HHH motif HHH_5 PF14520.6 OAG40850.1 - 0.019 15.6 0.2 0.83 10.3 0.0 2.5 2 0 0 2 2 2 0 Helix-hairpin-helix domain SRP-alpha_N PF04086.13 OAG40851.1 - 1.1 9.1 8.1 1.4 8.8 8.1 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal MAJIN PF15077.6 OAG40851.1 - 6.3 6.5 6.1 4.3 7.1 0.7 2.0 1 1 1 2 2 2 0 Membrane-anchored junction protein C2 PF00168.30 OAG40852.1 - 8.3e-27 93.5 0.0 1.8e-16 60.3 0.0 2.7 2 0 0 2 2 2 2 C2 domain Amidohydro_3 PF07969.11 OAG40852.1 - 1.1e-08 35.0 0.1 4e-07 29.9 0.0 2.2 2 0 0 2 2 2 1 Amidohydrolase family Amidohydro_1 PF01979.20 OAG40852.1 - 4.5e-08 32.8 0.0 7.9e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase family Neocarzinostat PF00960.18 OAG40852.1 - 0.11 12.4 2.1 0.26 11.3 2.1 1.5 1 0 0 1 1 1 0 Neocarzinostatin family Reprolysin_5 PF13688.6 OAG40853.1 - 9.5e-60 202.1 10.6 2.2e-59 200.9 10.6 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 OAG40853.1 - 1.6e-52 178.1 5.1 3.2e-52 177.1 5.1 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 OAG40853.1 - 9.9e-52 175.7 4.4 1.5e-51 175.1 4.4 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 OAG40853.1 - 2.3e-13 50.8 1.3 3.9e-13 50.0 0.1 2.0 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin PF01421.19 OAG40853.1 - 0.0021 18.0 11.0 0.064 13.1 11.0 2.9 1 1 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Pep_M12B_propep PF01562.19 OAG40853.1 - 0.0029 17.8 0.2 0.0066 16.7 0.2 1.5 1 0 0 1 1 1 1 Reprolysin family propeptide Peptidase_M66 PF10462.9 OAG40853.1 - 0.016 14.2 0.1 0.028 13.4 0.1 1.3 1 0 0 1 1 1 0 Peptidase M66 Aminotran_1_2 PF00155.21 OAG40854.1 - 5.5e-69 233.1 0.0 6.2e-69 232.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 OAG40854.1 - 0.0012 17.4 0.0 0.0019 16.8 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 OAG40854.1 - 0.062 12.2 0.0 0.17 10.8 0.0 1.6 2 0 0 2 2 2 0 Aminotransferase class-V Beta_elim_lyase PF01212.21 OAG40854.1 - 0.1 11.8 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase MgsA_C PF12002.8 OAG40855.1 - 1.7e-61 207.0 0.1 3.4e-61 206.0 0.0 1.5 2 0 0 2 2 1 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 OAG40855.1 - 1.5e-23 82.9 0.4 3.6e-23 81.7 0.4 1.6 1 0 0 1 1 1 1 AAA C-terminal domain AAA PF00004.29 OAG40855.1 - 1.4e-13 51.4 0.1 3.6e-13 50.1 0.1 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 OAG40855.1 - 1.4e-09 37.9 0.0 3.1e-09 36.8 0.0 1.5 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 OAG40855.1 - 3.9e-05 23.1 0.3 0.1 12.0 0.0 2.3 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 OAG40855.1 - 4.7e-05 23.8 0.7 0.07 13.5 0.0 3.2 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 OAG40855.1 - 5.5e-05 23.2 0.0 0.00063 19.8 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 OAG40855.1 - 0.00022 20.9 0.0 0.016 15.0 0.0 2.3 1 1 0 1 1 1 1 Sigma-54 interaction domain ResIII PF04851.15 OAG40855.1 - 0.00044 20.3 0.2 0.35 10.9 0.0 2.4 1 1 1 2 2 2 2 Type III restriction enzyme, res subunit AAA_22 PF13401.6 OAG40855.1 - 0.0024 18.1 0.3 0.015 15.5 0.3 2.4 1 1 0 1 1 1 1 AAA domain AAA_3 PF07726.11 OAG40855.1 - 0.0026 17.6 0.0 0.0056 16.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 OAG40855.1 - 0.0028 16.9 0.0 0.0047 16.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.6 OAG40855.1 - 0.0042 17.1 0.0 0.011 15.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 OAG40855.1 - 0.044 13.5 0.7 0.12 12.1 0.7 1.7 1 1 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.6 OAG40855.1 - 0.047 13.8 0.0 0.093 12.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain zf_C2H2_13 PF18508.1 OAG40855.1 - 0.057 13.0 0.3 0.26 10.9 0.7 1.9 2 0 0 2 2 2 0 Zinc finger domain zf-C2HC_2 PF13913.6 OAG40855.1 - 0.066 13.1 0.0 0.24 11.4 0.0 2.0 2 0 0 2 2 2 0 zinc-finger of a C2HC-type AAA_18 PF13238.6 OAG40855.1 - 0.13 12.8 0.0 0.34 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 OAG40855.1 - 0.15 12.1 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE TIP49 PF06068.13 OAG40855.1 - 0.16 11.2 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain NB-ARC PF00931.22 OAG40855.1 - 0.16 11.2 0.1 0.31 10.2 0.1 1.5 1 0 0 1 1 1 0 NB-ARC domain SKI PF01202.22 OAG40855.1 - 0.17 12.0 0.1 0.36 10.9 0.1 1.6 1 0 0 1 1 1 0 Shikimate kinase AAA_24 PF13479.6 OAG40855.1 - 0.19 11.4 0.0 0.32 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Pro_dh PF01619.18 OAG40857.1 - 4.3e-59 200.5 0.0 5.9e-59 200.0 0.0 1.2 1 0 0 1 1 1 1 Proline dehydrogenase DAO PF01266.24 OAG40857.1 - 4.5e-20 72.5 0.0 7.3e-20 71.8 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAG40857.1 - 0.0025 18.0 0.0 0.013 15.7 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Hrs_helical PF12210.8 OAG40857.1 - 0.15 12.6 0.1 0.39 11.3 0.1 1.7 1 0 0 1 1 1 0 Hepatocyte growth factor-regulated tyrosine kinase substrate NAD_Gly3P_dh_N PF01210.23 OAG40857.1 - 0.19 11.7 0.0 0.35 10.8 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Mito_carr PF00153.27 OAG40858.1 - 6.3e-57 189.5 3.1 3e-18 65.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.19 OAG40858.1 - 0.02 15.3 0.7 0.02 15.3 0.7 2.9 2 2 0 3 3 3 0 Tim17/Tim22/Tim23/Pmp24 family Cupin_1 PF00190.22 OAG40859.1 - 3.9e-07 29.8 0.0 5.6e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 OAG40859.1 - 1e-06 28.3 0.2 3e-05 23.6 0.2 2.3 1 1 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 OAG40859.1 - 0.05 13.3 0.1 0.31 10.8 0.1 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF861) ARD PF03079.14 OAG40859.1 - 0.12 12.5 0.0 0.18 11.9 0.0 1.2 1 0 0 1 1 1 0 ARD/ARD' family P5CR_dimer PF14748.6 OAG40860.1 - 7.4e-19 67.9 2.4 1.2e-18 67.3 2.4 1.3 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 OAG40860.1 - 3.1e-13 50.1 0.0 1.2e-12 48.2 0.0 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent MDMPI_C PF07398.11 OAG40860.1 - 0.1 13.5 0.0 0.26 12.2 0.0 1.7 1 0 0 1 1 1 0 MDMPI C-terminal domain DHDPS PF00701.22 OAG40861.1 - 9.6e-24 83.6 0.0 2.2e-16 59.4 0.0 2.1 2 0 0 2 2 2 2 Dihydrodipicolinate synthetase family Fungal_trans PF04082.18 OAG40862.1 - 1.7e-19 69.9 0.1 4.1e-19 68.7 0.1 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG40862.1 - 3.3e-06 27.1 14.3 5.6e-06 26.4 14.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Med13_C PF06333.12 OAG40862.1 - 0.14 11.4 2.1 0.3 10.3 2.1 1.5 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain Aldedh PF00171.22 OAG40863.1 - 1.6e-94 317.0 0.0 1.9e-94 316.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Aldedh PF00171.22 OAG40864.1 - 5.6e-139 463.6 0.1 6.6e-139 463.4 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 OAG40864.1 - 0.017 14.2 0.0 0.026 13.6 0.0 1.2 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) PagP PF07017.11 OAG40864.1 - 0.14 11.6 0.1 1 8.8 0.1 2.2 1 1 0 2 2 2 0 Antimicrobial peptide resistance and lipid A acylation protein PagP PGM_PMM_II PF02879.16 OAG40864.1 - 0.15 12.7 0.0 0.71 10.5 0.0 2.1 2 0 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II ArAE_2_N PF10337.9 OAG40865.1 - 7.8e-101 338.4 0.4 7.8e-101 338.4 0.4 2.1 3 0 0 3 3 3 1 Putative ER transporter, 6TM, N-terminal ArAE_2 PF10334.9 OAG40865.1 - 1.5e-46 159.1 0.0 1.4e-45 155.9 0.0 2.2 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 FUSC_2 PF13515.6 OAG40865.1 - 2.4e-08 34.1 17.4 2.4e-08 34.1 17.4 3.2 3 0 0 3 3 3 1 Fusaric acid resistance protein-like TraQ PF09679.10 OAG40865.1 - 0.08 12.9 0.3 0.38 10.7 0.3 2.2 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin chaperone (TraQ) Calreticulin PF00262.18 OAG40866.1 - 1.7e-171 570.1 17.3 1.7e-171 570.1 17.3 1.4 2 0 0 2 2 2 1 Calreticulin family OAD_gamma PF04277.13 OAG40866.1 - 2.7 8.6 4.6 2.1 9.0 0.2 3.0 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain Aldolase_II PF00596.21 OAG40867.1 - 8e-45 153.1 0.0 9.5e-45 152.8 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain GCN5L1 PF06320.13 OAG40868.1 - 4.4e-13 49.4 4.1 5.1e-13 49.2 4.1 1.0 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) DUF2884 PF11101.8 OAG40868.1 - 0.0034 16.9 0.7 0.0034 16.9 0.7 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF2884) Sec34 PF04136.15 OAG40868.1 - 0.013 15.4 0.6 0.017 15.0 0.6 1.3 1 0 0 1 1 1 0 Sec34-like family CHASE3 PF05227.13 OAG40868.1 - 0.015 15.2 1.3 0.015 15.2 1.3 1.9 1 1 0 2 2 2 0 CHASE3 domain Spc7 PF08317.11 OAG40868.1 - 0.03 13.2 5.3 0.041 12.8 5.3 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Baculo_PEP_C PF04513.12 OAG40868.1 - 0.033 14.2 3.5 0.085 12.9 3.5 1.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4515 PF14988.6 OAG40868.1 - 0.041 13.7 5.6 0.028 14.2 4.2 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4515) APG6_N PF17675.1 OAG40868.1 - 0.043 14.3 10.7 0.16 12.5 10.7 1.8 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF812 PF05667.11 OAG40868.1 - 0.053 12.4 7.6 0.061 12.2 7.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) TMPIT PF07851.13 OAG40868.1 - 0.055 12.7 1.6 0.069 12.4 1.6 1.1 1 0 0 1 1 1 0 TMPIT-like protein Rootletin PF15035.6 OAG40868.1 - 0.059 13.4 3.9 0.069 13.2 3.9 1.2 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion IL2 PF00715.17 OAG40868.1 - 0.091 12.7 0.7 0.11 12.5 0.7 1.1 1 0 0 1 1 1 0 Interleukin 2 DUF2968 PF11180.8 OAG40868.1 - 0.1 12.3 5.0 0.16 11.6 5.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) AAA_13 PF13166.6 OAG40868.1 - 0.11 11.1 5.8 0.13 10.9 5.8 1.0 1 0 0 1 1 1 0 AAA domain BLOC1_2 PF10046.9 OAG40868.1 - 0.15 12.3 4.6 0.28 11.5 4.6 1.5 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1664 PF07889.12 OAG40868.1 - 0.23 11.5 3.8 0.67 10.0 3.7 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF4208 PF13907.6 OAG40868.1 - 0.23 11.9 2.0 4.4 7.8 0.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4208) bZIP_1 PF00170.21 OAG40868.1 - 0.24 11.5 5.0 0.44 10.7 1.8 2.3 1 1 1 2 2 2 0 bZIP transcription factor SLATT_5 PF18160.1 OAG40868.1 - 0.3 10.4 2.9 0.43 9.9 2.6 1.4 1 1 1 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 DUF3450 PF11932.8 OAG40868.1 - 0.31 10.3 8.3 0.57 9.4 8.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) YabA PF06156.13 OAG40868.1 - 0.34 11.6 4.1 0.86 10.3 4.1 1.7 1 1 0 1 1 1 0 Initiation control protein YabA NYD-SP28_assoc PF14775.6 OAG40868.1 - 0.37 10.9 1.8 2.1 8.5 1.0 2.2 1 1 1 2 2 2 0 Sperm tail C-terminal domain DUF848 PF05852.11 OAG40868.1 - 0.51 10.4 6.8 0.63 10.1 5.7 1.5 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) TBCC_N PF16752.5 OAG40868.1 - 0.54 10.7 8.4 2.4 8.6 4.6 2.3 1 1 2 3 3 3 0 Tubulin-specific chaperone C N-terminal domain ATG16 PF08614.11 OAG40868.1 - 0.81 9.9 12.7 1.8 8.8 12.7 1.6 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Mt_ATP-synt_B PF05405.14 OAG40868.1 - 1.2 8.7 6.1 0.14 11.7 0.6 2.1 2 1 1 3 3 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) FUSC PF04632.12 OAG40868.1 - 1.6 7.1 3.7 1.8 7.0 3.7 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF4407 PF14362.6 OAG40868.1 - 1.8 7.8 9.0 2.3 7.5 9.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DivIC PF04977.15 OAG40868.1 - 4.2 7.2 6.5 3.4 7.5 2.5 2.4 1 1 1 2 2 2 0 Septum formation initiator Vps39_1 PF10366.9 OAG40869.1 - 1.3e-30 105.8 0.0 2.6e-29 101.7 0.0 2.7 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.9 OAG40869.1 - 1.7e-21 76.7 0.0 1.1e-20 74.1 0.0 2.4 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.22 OAG40869.1 - 1.6e-14 54.2 0.0 3.5e-14 53.1 0.0 1.5 1 1 0 1 1 1 1 CNH domain Clathrin PF00637.20 OAG40869.1 - 4.7e-09 36.3 2.2 3.2e-07 30.3 0.2 3.5 3 0 0 3 3 3 1 Region in Clathrin and VPS PPR PF01535.20 OAG40869.1 - 0.056 13.7 0.5 5.2 7.6 0.0 3.6 3 1 1 4 4 4 0 PPR repeat TPR_1 PF00515.28 OAG40869.1 - 0.087 12.7 0.8 7 6.7 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 OAG40869.1 - 0.09 13.3 2.0 9.3 6.8 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 OAG40869.1 - 2.9 9.0 7.1 14 6.8 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat Gon7 PF08738.10 OAG40870.1 - 2.6e-11 43.6 12.3 1.9e-10 40.8 8.9 2.1 1 1 1 2 2 2 2 Gon7 family Mit_ribos_Mrp51 PF11709.8 OAG40870.1 - 0.0095 15.6 3.7 0.011 15.4 3.7 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit GnsAB_toxin PF08178.11 OAG40870.1 - 0.027 14.4 1.3 0.04 13.8 0.8 1.6 1 1 0 1 1 1 0 GnsA/GnsB toxin of bacterial toxin-antitoxin system AMP-binding_C_2 PF14535.6 OAG40870.1 - 0.038 14.3 0.5 0.067 13.5 0.5 1.5 1 1 0 1 1 1 0 AMP-binding enzyme C-terminal domain DUF4611 PF15387.6 OAG40870.1 - 0.13 12.5 6.8 0.49 10.6 7.2 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4611) ESP PF16590.5 OAG40870.1 - 0.15 12.3 2.7 0.21 11.8 2.7 1.3 1 0 0 1 1 1 0 Exocrine gland-secreting peptide DUF5580 PF17743.1 OAG40870.1 - 0.16 10.5 7.6 0.19 10.2 7.6 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5580) RP-C_C PF11800.8 OAG40870.1 - 0.51 10.4 4.9 0.59 10.2 4.9 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region HbrB PF08539.11 OAG40871.1 - 9.3e-51 172.2 0.0 2.6e-50 170.7 0.0 1.8 1 0 0 1 1 1 1 HbrB-like PMC2NT PF08066.12 OAG40871.1 - 0.023 15.4 1.6 0.095 13.4 0.1 2.4 2 0 0 2 2 2 0 PMC2NT (NUC016) domain Abhydrolase_1 PF00561.20 OAG40872.1 - 3.6e-17 62.9 0.1 1.3e-16 61.1 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAG40872.1 - 4.4e-17 62.1 0.0 8.6e-16 57.9 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OAG40872.1 - 3.8e-12 47.3 0.0 4.6e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family PLDc_2 PF13091.6 OAG40872.1 - 0.0045 16.9 0.1 0.0073 16.2 0.1 1.3 1 0 0 1 1 1 1 PLD-like domain Peptidase_S9 PF00326.21 OAG40872.1 - 0.019 14.5 0.1 0.029 13.8 0.1 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family DLH PF01738.18 OAG40872.1 - 0.17 11.4 0.1 0.25 10.8 0.1 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family DUF3425 PF11905.8 OAG40873.1 - 9e-15 54.8 4.5 7.3e-14 51.8 4.5 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 OAG40873.1 - 0.0038 17.3 4.7 0.0064 16.6 4.7 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 OAG40873.1 - 0.22 11.7 6.4 0.36 11.0 6.4 1.3 1 0 0 1 1 1 0 Basic region leucine zipper Cu_bind_like PF02298.17 OAG40874.1 - 0.16 12.0 0.0 0.46 10.5 0.0 1.7 1 1 0 1 1 1 0 Plastocyanin-like domain Abhydrolase_3 PF07859.13 OAG40875.1 - 1e-36 126.8 0.0 1e-26 94.1 0.0 2.5 3 0 0 3 3 3 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 OAG40875.1 - 0.094 11.6 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Steryl acetyl hydrolase zinc_ribbon_9 PF14369.6 OAG40876.1 - 3.7e-05 23.9 2.7 3.7e-05 23.9 2.7 2.0 2 0 0 2 2 2 1 zinc-ribbon HypA PF01155.19 OAG40876.1 - 0.0093 16.0 2.6 0.013 15.5 0.6 2.0 2 0 0 2 2 2 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-RING_11 PF17123.5 OAG40876.1 - 0.063 13.0 0.7 0.16 11.8 0.7 1.7 1 0 0 1 1 1 0 RING-like zinc finger zinc-ribbons_6 PF07191.12 OAG40876.1 - 0.069 13.1 2.8 0.2 11.7 0.5 2.2 2 0 0 2 2 2 0 zinc-ribbons zf-UDP PF14569.6 OAG40876.1 - 0.12 12.6 1.4 9.2 6.5 0.1 2.5 2 0 0 2 2 2 0 Zinc-binding RING-finger zf-C3HC4_3 PF13920.6 OAG40876.1 - 0.12 12.3 2.9 0.91 9.4 0.3 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAG40876.1 - 0.3 11.4 7.1 4.7 7.6 2.4 2.4 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4 PF00097.25 OAG40876.1 - 0.33 10.9 4.1 1.8 8.5 1.1 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OAG40876.1 - 2 8.6 4.2 0.77 10.0 0.8 2.0 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Fis1_TPR_C PF14853.6 OAG40877.1 - 2.6e-26 91.4 2.8 4.5e-26 90.7 2.8 1.4 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 OAG40877.1 - 4.4e-18 64.7 0.1 7.3e-18 63.9 0.1 1.4 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.17 OAG40877.1 - 0.004 17.2 3.9 0.004 17.2 3.9 1.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 OAG40877.1 - 0.034 14.8 0.6 0.1 13.3 0.6 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF2957 PF11170.8 OAG40877.1 - 0.058 12.2 0.0 0.085 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2957) DUF2076 PF09849.9 OAG40877.1 - 0.13 12.3 0.0 0.17 11.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Spc24 PF08286.11 OAG40878.1 - 4.9e-36 123.2 4.0 7e-35 119.4 0.5 2.2 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 Cnn_1N PF07989.11 OAG40878.1 - 0.058 13.6 2.4 0.11 12.7 0.4 2.2 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 CLZ PF16526.5 OAG40878.1 - 0.086 13.2 8.1 0.44 11.0 2.5 2.4 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels APG6_N PF17675.1 OAG40878.1 - 0.17 12.4 11.4 0.31 11.6 11.4 1.5 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF4337 PF14235.6 OAG40878.1 - 0.19 11.9 1.5 0.29 11.2 1.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Prefoldin_2 PF01920.20 OAG40878.1 - 0.2 11.6 6.9 1.1 9.3 2.6 2.2 2 0 0 2 2 2 0 Prefoldin subunit SHE3 PF17078.5 OAG40878.1 - 0.28 10.8 8.1 0.49 10.1 0.8 2.2 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 FlaC_arch PF05377.11 OAG40878.1 - 0.34 11.3 3.2 15 6.1 0.7 2.9 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Uso1_p115_C PF04871.13 OAG40878.1 - 1.7 9.0 10.0 8.7 6.7 10.0 1.9 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region GAS PF13851.6 OAG40878.1 - 1.8 7.9 9.3 1.1 8.6 3.3 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Csm1_N PF18504.1 OAG40878.1 - 2.1 8.7 7.4 2.7 8.4 2.5 2.4 2 0 0 2 2 2 0 Csm1 N-terminal domain SlyX PF04102.12 OAG40878.1 - 2.2 9.0 8.2 3.2 8.4 2.1 2.5 1 1 1 2 2 2 0 SlyX Nup54 PF13874.6 OAG40878.1 - 3.3 7.8 12.0 19 5.3 10.8 2.5 2 1 0 2 2 2 0 Nucleoporin complex subunit 54 ADIP PF11559.8 OAG40878.1 - 6.4 6.8 11.8 1.1 9.3 2.8 2.2 1 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding S4 PF01479.25 OAG40879.1 - 4.9e-15 55.0 0.0 9e-15 54.1 0.0 1.5 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.6 OAG40879.1 - 0.057 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 S4 domain Pyr_redox_2 PF07992.14 OAG40880.1 - 2e-49 168.4 0.7 2.4e-49 168.1 0.7 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG40880.1 - 3.8e-19 69.1 0.4 7.6e-18 64.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAG40880.1 - 4.2e-17 62.5 0.2 6e-15 55.6 0.2 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 OAG40880.1 - 9.8e-05 22.7 0.3 0.0054 17.2 0.1 2.7 2 1 0 2 2 2 1 Putative NAD(P)-binding K_oxygenase PF13434.6 OAG40880.1 - 0.00016 21.0 0.1 0.011 14.9 0.0 3.0 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 OAG40880.1 - 0.00025 21.2 1.2 0.19 12.0 0.3 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 OAG40880.1 - 0.00034 19.9 0.3 0.0025 17.1 0.0 2.3 2 1 1 3 3 3 1 Thi4 family FAD_binding_3 PF01494.19 OAG40880.1 - 0.0075 15.6 0.0 1.8 7.8 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 OAG40880.1 - 0.0086 15.7 3.8 2.6 7.5 0.0 3.4 2 2 1 3 3 3 1 FAD dependent oxidoreductase GIDA PF01134.22 OAG40880.1 - 0.021 13.9 6.3 1.4 7.9 0.0 4.2 3 1 1 5 5 5 0 Glucose inhibited division protein A FAD_oxidored PF12831.7 OAG40880.1 - 0.025 13.9 1.8 0.65 9.3 0.3 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase Shikimate_DH PF01488.20 OAG40880.1 - 0.035 14.2 0.1 17 5.5 0.1 3.1 2 1 1 3 3 3 0 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.24 OAG40880.1 - 0.046 12.8 6.3 2.9 6.9 0.2 3.6 2 2 1 4 4 4 0 FAD binding domain malic PF00390.19 OAG40882.1 - 2.6e-63 213.1 0.0 3.8e-63 212.6 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Malic_M PF03949.15 OAG40882.1 - 2.5e-15 56.5 2.9 3.8e-15 55.9 2.9 1.3 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain Phage_int_SAM_5 PF13102.6 OAG40882.1 - 0.025 14.9 0.0 0.07 13.5 0.0 1.7 1 0 0 1 1 1 0 Phage integrase SAM-like domain Malic_M PF03949.15 OAG40883.1 - 2.5e-63 213.8 0.0 2.8e-63 213.6 0.0 1.0 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain Ldh_2 PF02615.14 OAG40884.1 - 8.9e-89 297.9 0.0 1e-88 297.7 0.0 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase DFRP_C PF16543.5 OAG40885.1 - 0.087 13.3 0.6 0.16 12.4 0.1 1.7 2 0 0 2 2 2 0 DRG Family Regulatory Proteins, Tma46 AbiTii PF18864.1 OAG40885.1 - 0.14 12.2 0.1 0.22 11.6 0.1 1.3 1 0 0 1 1 1 0 AbiTii Glyoxalase PF00903.25 OAG40886.1 - 2.9e-05 24.3 0.1 0.00062 20.0 0.1 2.2 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily adh_short_C2 PF13561.6 OAG40887.1 - 5.3e-43 147.2 0.0 7.1e-42 143.6 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG40887.1 - 4.5e-38 130.7 0.0 8.9e-37 126.4 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG40887.1 - 5.6e-12 45.9 0.0 8.3e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 OAG40887.1 - 0.0014 18.1 0.0 0.0053 16.2 0.0 1.8 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 OAG40887.1 - 0.0024 17.1 0.0 0.0035 16.5 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 OAG40887.1 - 0.034 13.6 0.1 0.17 11.3 0.1 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family RHH_3 PF12651.7 OAG40887.1 - 0.1 12.6 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Ribbon-helix-helix domain p450 PF00067.22 OAG40888.1 - 1.7e-42 145.8 0.0 2.4e-42 145.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 OAG40889.1 - 1.2e-32 113.3 32.4 1.2e-32 113.3 32.4 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily MAP17 PF15807.5 OAG40889.1 - 0.088 13.0 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Thioesterase PF00975.20 OAG40889.1 - 0.16 12.1 0.2 0.4 10.7 0.0 1.7 2 0 0 2 2 2 0 Thioesterase domain Wzz PF02706.15 OAG40889.1 - 0.79 10.1 6.9 72 3.8 0.0 4.3 4 0 0 4 4 4 0 Chain length determinant protein CPSase_L_D2 PF02786.17 OAG40891.1 - 1.2e-55 188.3 0.0 1.8e-55 187.7 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Carboxyl_trans PF01039.22 OAG40891.1 - 1.2e-44 152.8 0.1 1.3e-36 126.3 0.0 2.2 2 0 0 2 2 2 2 Carboxyl transferase domain Biotin_carb_N PF00289.22 OAG40891.1 - 1.2e-31 109.5 0.0 8.2e-31 106.8 0.0 2.4 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 OAG40891.1 - 4.2e-22 78.3 0.0 2.2e-21 76.0 0.0 2.1 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 OAG40891.1 - 5.4e-16 58.2 0.2 2.4e-15 56.1 0.3 2.1 2 0 0 2 2 2 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 OAG40891.1 - 8.8e-09 35.1 1.1 9.9e-06 25.3 0.1 2.8 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD_D23 PF16576.5 OAG40891.1 - 3.3e-05 23.2 2.1 0.14 11.4 0.5 2.4 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion ATP-grasp_3 PF02655.14 OAG40891.1 - 5e-05 23.4 0.0 0.0001 22.4 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.6 OAG40891.1 - 0.00011 22.9 0.1 0.037 14.7 0.0 2.7 2 0 0 2 2 2 1 HlyD family secretion protein ECH_1 PF00378.20 OAG40891.1 - 0.00082 18.8 0.2 0.0017 17.7 0.2 1.5 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ATPgrasp_ST PF14397.6 OAG40891.1 - 0.014 14.6 0.0 0.054 12.7 0.0 1.9 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp DUF2118 PF09891.9 OAG40891.1 - 0.03 14.3 0.0 0.073 13.0 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) NQRA PF05896.11 OAG40891.1 - 0.032 13.7 0.1 6.7 6.1 0.0 2.2 1 1 1 2 2 2 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) QRPTase_N PF02749.16 OAG40891.1 - 0.074 13.1 0.1 10 6.3 0.0 2.7 1 1 1 2 2 2 0 Quinolinate phosphoribosyl transferase, N-terminal domain RnfC_N PF13375.6 OAG40891.1 - 0.084 12.8 0.3 0.28 11.2 0.2 1.9 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain Fungal_trans_2 PF11951.8 OAG40892.1 - 6.7e-18 64.7 0.2 7.8e-18 64.4 0.2 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.25 OAG40893.1 - 2.4e-23 82.6 0.0 3.4e-23 82.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG40893.1 - 5e-17 62.2 0.0 6.8e-17 61.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG40893.1 - 1.6e-05 24.9 0.0 2.9e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 OAG40893.1 - 0.0045 16.9 0.0 0.0055 16.6 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding Lar_N PF09861.9 OAG40893.1 - 0.044 13.0 0.0 0.057 12.6 0.0 1.3 1 0 0 1 1 1 0 Lactate racemase N-terminal domain adh_short PF00106.25 OAG40894.1 - 1.3e-14 54.1 1.0 1.8e-14 53.6 1.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG40894.1 - 1.4e-13 50.9 2.2 2e-13 50.4 2.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase RmlD_sub_bind PF04321.17 OAG40894.1 - 5.6e-05 22.4 0.4 9.2e-05 21.7 0.4 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 OAG40894.1 - 0.00036 20.1 0.2 0.00043 19.8 0.2 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DFP PF04127.15 OAG40894.1 - 0.027 14.3 1.5 0.039 13.8 1.5 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein NmrA PF05368.13 OAG40894.1 - 0.066 12.8 1.4 0.23 11.0 0.3 2.1 2 0 0 2 2 2 0 NmrA-like family adh_short PF00106.25 OAG40895.1 - 7.3e-11 41.9 0.1 1.1e-10 41.3 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG40895.1 - 2e-10 40.6 0.0 3.4e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Cu_amine_oxid PF01179.20 OAG40896.1 - 2.1e-83 280.6 0.6 5.9e-57 193.4 0.0 3.3 1 1 1 2 2 2 2 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 OAG40896.1 - 6.4e-05 23.3 0.0 0.00015 22.1 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain RFX1_trans_act PF04589.13 OAG40896.1 - 0.12 12.5 0.1 0.25 11.5 0.1 1.4 1 0 0 1 1 1 0 RFX1 transcription activation region Aa_trans PF01490.18 OAG40898.1 - 3.6e-06 26.0 0.9 4.2e-06 25.7 0.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Asp_Glu_race_2 PF14669.6 OAG40898.1 - 0.033 13.9 0.2 0.042 13.5 0.2 1.1 1 0 0 1 1 1 0 Putative aspartate racemase Methyltransf_2 PF00891.18 OAG40899.1 - 9.5e-17 61.0 0.0 5.4e-16 58.5 0.0 2.1 1 1 0 1 1 1 1 O-methyltransferase domain Methyltransf_23 PF13489.6 OAG40900.1 - 8e-24 84.3 0.0 2e-23 83.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG40900.1 - 1.2e-11 45.2 0.0 4.6e-11 43.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG40900.1 - 6.2e-11 42.8 0.0 1.2e-10 41.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG40900.1 - 1.1e-10 42.1 0.0 1.5e-09 38.5 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG40900.1 - 9.4e-09 35.2 0.0 0.0023 17.8 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain MTS PF05175.14 OAG40900.1 - 0.00024 20.7 0.0 0.0048 16.5 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase small domain DUF938 PF06080.12 OAG40900.1 - 0.011 15.5 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF938) PrmA PF06325.13 OAG40900.1 - 0.019 14.3 0.0 0.035 13.5 0.0 1.5 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.17 OAG40900.1 - 0.028 13.9 0.0 0.082 12.4 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase Ribosomal_L29 PF00831.23 OAG40900.1 - 0.036 14.0 0.1 0.064 13.2 0.1 1.4 1 0 0 1 1 1 0 Ribosomal L29 protein Methyltransf_16 PF10294.9 OAG40900.1 - 0.046 13.5 0.0 0.073 12.8 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase Inositol_P PF00459.25 OAG40901.1 - 5.6e-65 219.6 0.0 6.5e-65 219.3 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Zn_clus PF00172.18 OAG40902.1 - 3.1e-08 33.6 11.9 4.9e-08 33.0 11.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TetR_C_15 PF17918.1 OAG40902.1 - 1.9 9.3 5.6 20 6.0 0.3 3.8 4 1 1 5 5 5 0 Tetracyclin repressor-like, C-terminal domain Unstab_antitox PF09720.10 OAG40902.1 - 3 8.0 4.7 1.9 8.6 0.1 3.0 3 0 0 3 3 3 0 Putative addiction module component Sugar_tr PF00083.24 OAG40903.1 - 7.7e-81 272.2 21.5 8.9e-81 272.0 21.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG40903.1 - 1.8e-12 46.9 36.8 1.8e-12 46.9 36.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily PUCC PF03209.15 OAG40903.1 - 0.97 8.4 17.2 0.017 14.1 2.1 2.9 2 2 2 4 4 4 0 PUCC protein DUF3792 PF12670.7 OAG40903.1 - 7.1 6.8 25.6 0.45 10.7 0.1 4.1 3 2 1 4 4 4 0 Protein of unknown function (DUF3792) 2H-phosphodiest PF08975.10 OAG40904.1 - 2.4e-19 69.4 0.0 4.3e-19 68.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1868) LigT_PEase PF02834.16 OAG40904.1 - 5.2e-06 26.6 0.0 0.048 13.9 0.0 2.7 3 0 0 3 3 3 2 LigT like Phosphoesterase 2_5_RNA_ligase2 PF13563.6 OAG40904.1 - 0.00049 20.0 0.1 0.0013 18.7 0.1 1.8 1 1 0 1 1 1 1 2'-5' RNA ligase superfamily FlaE PF07559.14 OAG40904.1 - 0.012 16.2 0.0 0.036 14.6 0.0 1.8 2 0 0 2 2 2 0 Flagellar basal body protein FlaE PCI PF01399.27 OAG40905.1 - 2.3e-12 47.4 0.0 7.9e-12 45.6 0.0 1.9 2 0 0 2 2 2 1 PCI domain RPN7 PF10602.9 OAG40905.1 - 0.0049 16.6 0.6 0.0087 15.8 0.6 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 p450 PF00067.22 OAG40906.1 - 4.5e-98 329.0 0.0 5.8e-98 328.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Ribosomal_L15e PF00827.17 OAG40906.1 - 0.12 12.1 0.3 0.28 10.9 0.3 1.6 1 1 0 1 1 1 0 Ribosomal L15 SpoIIE PF07228.12 OAG40907.1 - 2.5e-09 37.4 0.1 1.1e-08 35.2 0.1 2.0 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 OAG40907.1 - 8.4e-08 32.2 0.0 0.0022 17.7 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 OAG40907.1 - 1.1e-06 28.5 0.1 2.5e-06 27.3 0.1 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C TPR_1 PF00515.28 OAG40908.1 - 2.3e-10 39.9 2.1 0.00038 20.1 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 OAG40908.1 - 8.1e-09 34.9 3.9 0.066 13.4 0.0 4.3 4 0 0 4 4 3 3 Tetratricopeptide repeat ANAPC3 PF12895.7 OAG40908.1 - 6.3e-06 26.3 1.7 1.8e-05 24.8 1.1 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 SET PF00856.28 OAG40908.1 - 0.00018 22.0 0.0 0.62 10.4 0.0 2.6 2 0 0 2 2 2 2 SET domain TPR_16 PF13432.6 OAG40908.1 - 0.00042 20.9 0.2 0.053 14.2 0.0 3.5 5 0 0 5 5 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 OAG40908.1 - 0.00057 20.3 1.3 0.03 15.0 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat SRP_TPR_like PF17004.5 OAG40908.1 - 0.0014 18.6 1.8 0.0021 18.1 0.5 2.0 2 0 0 2 2 1 1 Putative TPR-like repeat TPR_11 PF13414.6 OAG40908.1 - 0.0067 16.1 0.0 0.0067 16.1 0.0 2.3 3 0 0 3 3 3 1 TPR repeat TPR_19 PF14559.6 OAG40908.1 - 0.012 16.1 1.1 2.9 8.5 0.0 2.9 2 1 1 3 3 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 OAG40908.1 - 0.015 15.4 1.6 0.074 13.1 0.3 2.6 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_12 PF13424.6 OAG40908.1 - 0.016 15.4 0.2 9.3 6.6 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 OAG40908.1 - 0.022 15.6 1.3 1.2 10.2 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 OAG40908.1 - 0.044 13.9 0.1 2.1 8.5 0.0 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 OAG40908.1 - 0.052 13.8 7.5 15 6.1 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 OAG40908.1 - 0.14 12.6 0.1 2.5 8.5 0.0 2.3 2 0 0 2 2 2 0 Alkyl sulfatase dimerisation zf-C2H2_4 PF13894.6 OAG40909.1 - 3.4e-09 36.7 23.7 0.012 16.4 0.3 6.8 7 0 0 7 7 7 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OAG40909.1 - 1.1e-08 35.2 14.9 0.0001 22.5 1.0 5.4 5 1 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 OAG40909.1 - 1.1e-08 35.0 20.5 0.00075 19.8 0.6 6.2 6 0 0 6 6 6 3 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 OAG40909.1 - 0.00062 20.1 2.9 0.00062 20.1 2.9 3.3 1 1 2 3 3 3 1 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.6 OAG40909.1 - 0.0021 18.4 10.4 1.6 9.3 0.1 4.7 4 0 0 4 4 4 2 Zinc-finger double domain zf-met PF12874.7 OAG40909.1 - 0.035 14.5 0.3 0.035 14.5 0.3 5.8 6 1 0 6 6 6 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 OAG40909.1 - 0.041 13.9 0.1 0.041 13.9 0.1 3.5 4 0 0 4 4 4 0 C2H2-type zinc finger zinc_ribbon_5 PF13719.6 OAG40909.1 - 0.073 12.8 0.6 0.073 12.8 0.6 4.5 5 0 0 5 5 5 0 zinc-ribbon domain zf_UBZ PF18439.1 OAG40909.1 - 0.24 11.0 9.9 2.1 8.0 0.1 5.0 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger zf-C2H2_3rep PF18868.1 OAG40909.1 - 0.81 10.4 10.9 17 6.1 1.4 4.3 2 1 3 5 5 5 0 Zinc finger C2H2-type, 3 repeats DZR PF12773.7 OAG40909.1 - 6.2 6.9 25.1 1.1 9.3 0.3 4.4 4 1 0 4 4 4 0 Double zinc ribbon Rpr2 PF04032.16 OAG40909.1 - 7.1 7.0 14.6 24 5.3 0.1 3.7 2 1 1 3 3 3 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Vta1 PF04652.16 OAG40910.1 - 5.8e-53 178.8 0.8 5.8e-53 178.8 0.8 1.5 2 0 0 2 2 2 1 Vta1 like Vta1_C PF18097.1 OAG40910.1 - 2.9e-16 58.9 0.4 1.6e-15 56.5 0.0 2.3 2 0 0 2 2 2 1 Vta1 C-terminal domain Herpes_UL17 PF04559.12 OAG40910.1 - 0.36 9.6 2.1 0.49 9.1 2.1 1.2 1 0 0 1 1 1 0 Herpesvirus UL17 protein NCBP3 PF10309.9 OAG40911.1 - 2.6e-19 68.8 0.4 4.1e-19 68.2 0.4 1.3 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 RNA_bind PF08675.11 OAG40911.1 - 0.0053 16.8 0.1 0.0094 16.0 0.1 1.3 1 0 0 1 1 1 1 RNA binding domain TauD PF02668.16 OAG40912.1 - 3.3e-60 204.2 0.2 4e-60 203.9 0.2 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family RRN3 PF05327.11 OAG40913.1 - 1.4 7.4 8.7 1.9 6.9 8.7 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Nop14 PF04147.12 OAG40913.1 - 2.3 6.4 14.8 3.8 5.6 14.8 1.3 1 0 0 1 1 1 0 Nop14-like family SNase PF00565.17 OAG40914.1 - 2.1e-20 73.2 0.4 3.4e-20 72.5 0.4 1.3 1 0 0 1 1 1 1 Staphylococcal nuclease homologue WD40 PF00400.32 OAG40915.1 - 0.0013 19.5 3.3 3.2 8.8 0.1 4.2 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG40915.1 - 0.045 14.0 0.0 0.14 12.5 0.0 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain Hydrolase_4 PF12146.8 OAG40916.1 - 1.6e-43 148.7 0.0 2e-43 148.4 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OAG40916.1 - 5.7e-13 50.0 0.0 8.1e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAG40916.1 - 1.7e-11 44.3 0.2 2.5e-10 40.5 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.18 OAG40916.1 - 8.8e-07 28.7 0.0 0.0027 17.3 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 OAG40916.1 - 0.00018 21.4 0.0 2.4 7.9 0.0 3.2 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 OAG40916.1 - 0.002 17.6 0.0 1.4 8.4 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Chlorophyllase2 PF12740.7 OAG40916.1 - 0.0077 15.2 0.0 0.017 14.1 0.0 1.4 1 1 0 1 1 1 1 Chlorophyllase enzyme Prok-E2_B PF14461.6 OAG40916.1 - 0.013 15.2 0.0 0.035 13.8 0.0 1.7 1 0 0 1 1 1 0 Prokaryotic E2 family B DUF1749 PF08538.10 OAG40916.1 - 0.049 12.7 0.0 0.068 12.2 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1749) DUF915 PF06028.11 OAG40916.1 - 0.049 13.0 0.0 0.085 12.2 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Chlorophyllase PF07224.11 OAG40916.1 - 0.065 12.2 0.1 0.17 10.9 0.1 1.6 1 1 0 1 1 1 0 Chlorophyllase Esterase PF00756.20 OAG40916.1 - 0.11 12.1 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 Putative esterase DUF900 PF05990.12 OAG40916.1 - 0.14 11.6 0.0 11 5.5 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_1 PF00561.20 OAG40918.1 - 2.1e-30 106.3 0.0 1.9e-29 103.1 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG40918.1 - 5.8e-16 59.8 1.2 7.3e-16 59.4 1.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG40918.1 - 8.7e-12 44.8 0.0 4.2e-06 26.2 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Ndr PF03096.14 OAG40918.1 - 3.5e-07 29.2 0.0 1.2e-05 24.2 0.0 2.1 2 0 0 2 2 2 1 Ndr family Abhydrolase_4 PF08386.10 OAG40918.1 - 0.0028 17.7 0.0 0.0043 17.1 0.0 1.3 1 0 0 1 1 1 1 TAP-like protein DUF915 PF06028.11 OAG40918.1 - 0.0058 16.0 0.0 0.008 15.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Peptidase_S9 PF00326.21 OAG40918.1 - 0.014 14.9 0.0 1.7 8.0 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_5 PF12695.7 OAG40918.1 - 0.014 15.1 0.0 0.15 11.8 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 OAG40918.1 - 0.046 13.6 0.0 0.095 12.5 0.0 1.6 1 1 1 2 2 2 0 alpha/beta hydrolase fold Thioesterase PF00975.20 OAG40918.1 - 0.062 13.4 0.0 0.095 12.8 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Esterase PF00756.20 OAG40918.1 - 0.072 12.7 0.0 0.089 12.4 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Say1_Mug180 PF10340.9 OAG40918.1 - 0.093 11.6 0.0 0.13 11.1 0.0 1.1 1 0 0 1 1 1 0 Steryl acetyl hydrolase Lipase_3 PF01764.25 OAG40918.1 - 0.16 11.8 0.1 0.27 11.1 0.1 1.3 1 0 0 1 1 1 0 Lipase (class 3) DUF1057 PF06342.12 OAG40918.1 - 0.19 10.7 0.0 0.26 10.3 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) PAF-AH_p_II PF03403.13 OAG40918.1 - 0.22 10.0 0.0 0.31 9.5 0.0 1.1 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II RsgA_GTPase PF03193.16 OAG40918.1 - 0.23 11.3 0.1 0.71 9.8 0.1 1.7 2 0 0 2 2 2 0 RsgA GTPase RNA_pol_Rpb6 PF01192.22 OAG40919.1 - 7.8e-17 60.9 0.8 1.7e-16 59.9 0.1 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb6 Pox_RNA_Pol_19 PF05320.12 OAG40919.1 - 0.038 14.0 0.1 0.049 13.6 0.1 1.1 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit zf-C2H2 PF00096.26 OAG40920.1 - 3.1e-26 90.3 59.6 1.8e-05 24.9 0.4 10.0 10 0 0 10 10 10 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAG40920.1 - 2.5e-22 77.6 50.5 0.0025 18.5 0.4 9.9 10 0 0 10 10 9 8 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OAG40920.1 - 2.3e-11 43.6 55.6 1.1e-05 25.6 2.5 10.2 10 0 0 10 10 10 5 Zinc-finger double domain zf-C2H2_11 PF16622.5 OAG40920.1 - 2.6e-06 27.1 14.8 0.75 9.6 0.1 6.4 7 0 0 7 7 7 3 zinc-finger C2H2-type zf-C2H2_aberr PF17017.5 OAG40920.1 - 3.6e-06 27.2 20.9 0.32 11.1 6.3 5.1 2 1 2 4 4 4 3 Aberrant zinc-finger zf-H2C2_5 PF13909.6 OAG40920.1 - 6.4e-06 25.8 39.8 0.55 10.0 0.2 9.0 8 0 0 8 8 8 5 C2H2-type zinc-finger domain FOXP-CC PF16159.5 OAG40920.1 - 6.2e-05 23.6 31.9 0.48 11.1 0.2 8.4 4 2 5 9 9 9 2 FOXP coiled-coil domain zf-C2H2_3rep PF18868.1 OAG40920.1 - 0.00033 21.3 21.0 0.025 15.2 0.5 5.1 1 1 4 5 5 5 2 Zinc finger C2H2-type, 3 repeats zf-C2H2_8 PF15909.5 OAG40920.1 - 0.00038 20.7 20.7 0.008 16.4 0.4 4.3 3 1 1 4 4 4 2 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 OAG40920.1 - 0.21 11.9 26.2 4.5 7.7 0.1 7.2 8 0 0 8 8 8 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OAG40920.1 - 0.22 12.0 0.1 0.22 12.0 0.1 6.8 8 0 0 8 8 7 0 Zinc-finger of C2H2 type zf_Hakai PF18408.1 OAG40920.1 - 1.1 9.0 0.0 1.1 9.0 0.0 5.8 6 0 0 6 6 6 0 C2H2 Hakai zinc finger domain zf-C2H2_6 PF13912.6 OAG40920.1 - 1.6 8.8 33.7 2.6 8.1 0.3 8.2 9 0 0 9 9 8 0 C2H2-type zinc finger zf-TRAF PF02176.18 OAG40920.1 - 2.9 8.7 27.2 0.23 12.2 7.2 5.7 4 1 2 6 6 6 0 TRAF-type zinc finger Peptidase_S15 PF02129.18 OAG40921.1 - 1.6e-42 146.0 0.0 9.9e-42 143.4 0.0 2.0 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 OAG40921.1 - 3.1e-06 27.3 0.0 5.4e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Sulfotransfer_4 PF17784.1 OAG40922.1 - 4.2e-72 242.5 0.0 5.2e-72 242.2 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OAG40922.1 - 1.2e-06 29.1 0.2 0.00067 20.1 0.1 2.6 2 1 1 3 3 3 2 Sulfotransferase family Arylsulfotran_2 PF14269.6 OAG40923.1 - 7.7e-58 196.2 3.6 1.2e-57 195.6 3.6 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 OAG40923.1 - 7.8e-17 61.2 2.9 1.1e-15 57.5 2.9 2.3 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) DUF2721 PF11026.8 OAG40923.1 - 0.087 12.7 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) FAM176 PF14851.6 OAG40923.1 - 1.5 8.5 4.3 2.6 7.7 4.3 1.3 1 0 0 1 1 1 0 FAM176 family MFS_1 PF07690.16 OAG40924.1 - 1.6e-17 63.5 17.4 1.6e-17 63.5 17.4 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Brix PF04427.18 OAG40926.1 - 7.6e-29 101.2 0.0 1e-28 100.8 0.0 1.2 1 0 0 1 1 1 1 Brix domain Tim17 PF02466.19 OAG40927.1 - 4.7e-13 49.5 0.3 7.9e-13 48.8 0.3 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Flavodoxin_5 PF12724.7 OAG40929.1 - 1.4e-26 93.5 0.0 1.6e-26 93.2 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin domain Flavodoxin_1 PF00258.25 OAG40929.1 - 3.1e-05 24.2 0.0 3.6e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_3 PF12641.7 OAG40929.1 - 0.0088 15.8 0.0 0.011 15.4 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin domain PaRep2b PF07775.11 OAG40929.1 - 0.047 12.2 0.0 0.065 11.7 0.0 1.1 1 0 0 1 1 1 0 PaRep2b protein RNase_H_2 PF13482.6 OAG40929.1 - 0.12 12.4 0.0 0.17 11.9 0.0 1.2 1 0 0 1 1 1 0 RNase_H superfamily HLH PF00010.26 OAG40931.1 - 4e-08 33.1 0.3 1.4e-07 31.4 0.0 2.0 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain PspB PF06667.12 OAG40931.1 - 0.089 12.9 0.1 0.089 12.9 0.1 2.2 2 0 0 2 2 2 0 Phage shock protein B MARVEL PF01284.23 OAG40932.1 - 1.2e-05 25.4 9.1 1.6e-05 25.0 9.1 1.2 1 0 0 1 1 1 1 Membrane-associating domain DUF3429 PF11911.8 OAG40932.1 - 0.032 14.5 2.2 0.058 13.7 2.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3429) Prok-E2_B PF14461.6 OAG40932.1 - 0.16 11.7 0.1 0.23 11.2 0.1 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B V-SNARE_C PF12352.8 OAG40935.1 - 5.3e-06 26.6 11.5 16 5.9 0.0 6.0 3 2 3 6 6 6 2 Snare region anchored in the vesicle membrane C-terminus RIIa PF02197.17 OAG40935.1 - 1.9e-05 24.2 10.6 4.3 7.1 0.0 7.0 7 0 0 7 7 7 2 Regulatory subunit of type II PKA R-subunit T3SS_basalb_I PF17001.5 OAG40935.1 - 0.0038 17.8 9.9 2 9.1 0.4 3.4 1 1 2 3 3 3 3 Type III secretion basal body protein I, YscI, HrpB, PscI DNAP_B_exo_N PF08452.10 OAG40935.1 - 0.39 10.2 32.9 2 7.9 0.1 6.6 7 0 0 7 7 7 0 DNA polymerase family B exonuclease domain, N-terminal TetR_C_23 PF17931.1 OAG40935.1 - 1.2 9.3 5.3 11 6.2 0.4 2.8 1 1 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain FliN_N PF16973.5 OAG40935.1 - 1.3 8.9 15.1 19 5.1 0.2 5.1 2 1 4 6 6 6 0 Flagellar motor switch protein FliN N-terminal DUF4381 PF14316.6 OAG40935.1 - 3.1 8.0 20.3 9.2 6.5 2.7 4.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4381) But2 PF09792.9 OAG40936.1 - 3e-40 137.9 2.8 3.6e-40 137.6 2.8 1.1 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain Acetyltransf_1 PF00583.25 OAG40938.1 - 1.2e-12 48.1 0.0 1.7e-12 47.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OAG40938.1 - 4.6e-11 42.8 0.0 8.8e-11 41.8 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OAG40938.1 - 2.2e-09 37.6 0.0 3.2e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAG40938.1 - 9.9e-09 35.1 0.0 1.4e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 OAG40938.1 - 0.0048 17.0 0.0 0.0076 16.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain dCMP_cyt_deam_1 PF00383.23 OAG40939.1 - 2.6e-13 49.7 0.0 3.5e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 OAG40939.1 - 1.2e-05 25.5 0.1 1.4e-05 25.3 0.1 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 OAG40939.1 - 0.00043 19.9 0.6 0.061 12.9 0.1 2.1 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases tRNA-synt_2b PF00587.25 OAG40939.1 - 0.19 11.7 0.0 0.28 11.1 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) DUF1152 PF06626.12 OAG40940.1 - 0.0022 17.3 1.2 1.3 8.2 0.1 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1152) AAA_25 PF13481.6 OAG40940.1 - 0.029 14.0 0.1 0.45 10.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain SL4P PF17618.2 OAG40940.1 - 0.055 13.5 0.0 0.35 11.0 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized Strongylid L4 protein Clr5 PF14420.6 OAG40941.1 - 1.5e-19 70.0 0.6 3.2e-19 68.9 0.6 1.6 1 0 0 1 1 1 1 Clr5 domain TPR_2 PF07719.17 OAG40941.1 - 5.7e-05 22.9 3.2 0.0018 18.2 0.5 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 OAG40941.1 - 0.0077 16.7 0.8 0.27 11.7 0.5 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 OAG40941.1 - 0.011 15.6 1.5 0.24 11.3 0.3 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_MalT PF17874.1 OAG40941.1 - 0.014 14.8 1.6 0.16 11.3 1.8 2.2 1 1 1 2 2 2 0 MalT-like TPR region TPR_14 PF13428.6 OAG40941.1 - 0.045 14.6 3.7 4.6 8.3 0.2 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 OAG40941.1 - 0.32 10.7 3.9 0.46 10.2 0.1 2.9 3 0 0 3 3 3 0 TPR repeat TPR_12 PF13424.6 OAG40941.1 - 0.33 11.3 6.9 0.91 9.9 2.7 3.2 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 OAG40941.1 - 1.5 9.6 4.0 4.5 8.1 0.3 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.14 OAG40941.1 - 9.6 7.2 10.9 9 7.3 0.9 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat CLP_protease PF00574.23 OAG40942.1 - 2.3e-67 226.4 0.1 3e-67 226.0 0.1 1.1 1 0 0 1 1 1 1 Clp protease DUF1746 PF08508.10 OAG40943.1 - 2e-12 47.5 0.9 2.7e-12 47.0 0.9 1.2 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1746) HSP70 PF00012.20 OAG40944.1 - 1.3e-09 36.9 0.0 2.9e-09 35.7 0.0 1.6 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 OAG40944.1 - 4.5e-05 22.4 0.1 0.00042 19.2 0.1 2.2 2 0 0 2 2 2 1 MreB/Mbl protein Rep_fac_C PF08542.11 OAG40946.1 - 8.9e-12 45.3 0.0 2.1e-11 44.1 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.29 OAG40946.1 - 3e-11 43.9 0.0 6.4e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 OAG40946.1 - 4.9e-09 36.2 0.0 4.8e-08 33.0 0.0 2.3 2 1 0 2 2 2 1 DNA polymerase III, delta subunit Rad17 PF03215.15 OAG40946.1 - 2.3e-05 24.4 0.0 4e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain RuvB_N PF05496.12 OAG40946.1 - 4.8e-05 23.1 0.0 0.00024 20.9 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 OAG40946.1 - 0.00016 21.9 0.0 0.00078 19.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_assoc_2 PF16193.5 OAG40946.1 - 0.00025 21.3 0.3 0.00075 19.8 0.0 2.0 2 0 0 2 2 1 1 AAA C-terminal domain Mg_chelatase PF01078.21 OAG40946.1 - 0.0003 20.2 0.0 0.005 16.2 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_11 PF13086.6 OAG40946.1 - 0.00048 20.0 0.1 0.0033 17.3 0.0 2.0 1 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OAG40946.1 - 0.00064 20.1 0.1 0.0035 17.7 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 OAG40946.1 - 0.0021 17.8 0.0 0.0046 16.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OAG40946.1 - 0.0023 18.3 0.0 0.0064 16.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 OAG40946.1 - 0.017 15.1 0.0 1.3 9.0 0.0 2.4 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit DUF815 PF05673.13 OAG40946.1 - 0.018 14.2 0.0 0.036 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RNA_helicase PF00910.22 OAG40946.1 - 0.049 14.0 0.0 0.26 11.7 0.0 2.3 2 1 0 2 2 2 0 RNA helicase DUF2075 PF09848.9 OAG40946.1 - 0.054 12.7 0.0 0.13 11.5 0.0 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Sec20 PF03908.13 OAG40947.1 - 1.9e-12 47.0 3.1 7.2e-12 45.1 0.1 2.9 3 0 0 3 3 3 1 Sec20 TamB PF04357.13 OAG40947.1 - 0.046 13.0 1.9 0.047 12.9 0.3 1.7 2 0 0 2 2 2 0 TamB, inner membrane protein subunit of TAM complex Tweety PF04906.13 OAG40947.1 - 0.1 11.3 1.0 1.5 7.4 0.1 2.3 2 0 0 2 2 2 0 Tweety MRP_L53 PF10780.9 OAG40948.1 - 1.1e-15 57.5 0.2 1.6e-15 57.0 0.2 1.3 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 YvbH_ext PF11724.8 OAG40948.1 - 0.14 12.5 0.0 0.24 11.8 0.0 1.3 1 0 0 1 1 1 0 YvbH-like oligomerisation region Dus PF01207.17 OAG40949.1 - 1.1e-44 152.8 1.3 1.6e-44 152.2 0.0 1.9 2 1 0 2 2 2 1 Dihydrouridine synthase (Dus) Pyrophosphatase PF00719.19 OAG40950.1 - 2.8e-57 193.0 0.1 3.9e-57 192.5 0.1 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase MFS_2 PF13347.6 OAG40950.1 - 1.8e-09 36.7 7.3 3.7e-09 35.6 7.3 1.4 1 0 0 1 1 1 1 MFS/sugar transport protein PGF-CTERM PF18204.1 OAG40951.1 - 0.84 9.7 0.1 0.84 9.7 0.1 3.3 3 0 0 3 3 3 0 PGF-CTERM motif DUF4418 PF14387.6 OAG40951.1 - 1.2 9.4 4.2 9.8 6.4 0.4 3.4 2 2 0 2 2 2 0 Domain of unknown function (DUF4418) Ribosomal_L35Ae PF01247.18 OAG40952.1 - 6.4e-45 151.3 0.2 7.2e-45 151.1 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 OAG40952.1 - 6.9e-05 23.0 0.1 0.036 14.3 0.0 2.1 2 0 0 2 2 2 2 RimM N-terminal domain G6PD_C PF02781.16 OAG40953.1 - 2.2e-115 384.9 0.0 3.4e-115 384.2 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 OAG40953.1 - 1.9e-61 207.8 0.0 3.3e-61 207.0 0.0 1.4 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain DUF2406 PF10295.9 OAG40954.1 - 2.1e-21 76.3 3.1 2.6e-21 76.0 0.6 2.5 3 0 0 3 3 3 1 Uncharacterised protein (DUF2406) KIAA1328 PF15369.6 OAG40954.1 - 3.7 7.3 6.1 2.3 8.0 1.7 2.0 2 0 0 2 2 2 0 Uncharacterised protein KIAA1328 VMA21 PF09446.10 OAG40955.1 - 6.7e-15 54.9 10.8 9.7e-15 54.4 10.8 1.2 1 0 0 1 1 1 1 VMA21-like domain SNF2_N PF00176.23 OAG40956.1 - 1e-53 182.3 0.1 2.3e-53 181.1 0.0 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OAG40956.1 - 1.3e-19 70.6 0.2 4.7e-18 65.6 0.0 3.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG40956.1 - 5e-09 36.4 0.0 1.4e-08 34.9 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 OAG40956.1 - 0.0042 16.3 0.0 0.009 15.2 0.0 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Pex14_N PF04695.13 OAG40956.1 - 0.015 15.9 4.5 0.015 15.9 4.5 3.1 4 0 0 4 4 4 0 Peroxisomal membrane anchor protein (Pex14p) conserved region HHH_3 PF12836.7 OAG40956.1 - 0.061 13.6 0.0 0.17 12.2 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif Sugar_tr PF00083.24 OAG40958.1 - 1.5e-73 248.2 22.1 1.5e-73 248.2 22.1 1.5 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG40958.1 - 3.1e-20 72.4 28.5 3.1e-20 72.4 28.5 2.4 1 1 0 2 2 2 1 Major Facilitator Superfamily DUF983 PF06170.12 OAG40958.1 - 0.14 12.6 0.1 0.14 12.6 0.1 3.6 4 1 1 5 5 5 0 Protein of unknown function (DUF983) Myb_DNA-bind_4 PF13837.6 OAG40959.1 - 0.00077 19.8 0.0 0.0046 17.3 0.1 2.2 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain AAA_16 PF13191.6 OAG40960.1 - 8e-11 42.6 0.2 9.8e-10 39.1 0.0 2.8 2 1 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 OAG40960.1 - 1.3e-08 34.9 0.0 3.9e-08 33.4 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 OAG40960.1 - 4.7e-06 26.9 0.1 0.00042 20.6 0.0 3.5 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 OAG40960.1 - 0.00077 19.8 0.3 0.031 14.7 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_18 PF13238.6 OAG40960.1 - 0.002 18.7 0.0 0.013 16.0 0.0 2.6 1 1 0 1 1 1 1 AAA domain Ploopntkinase3 PF18751.1 OAG40960.1 - 0.019 14.9 0.0 0.049 13.5 0.0 1.6 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 Stn1 PF10451.9 OAG40960.1 - 0.031 13.3 0.0 0.23 10.4 0.0 2.0 2 0 0 2 2 2 0 Telomere regulation protein Stn1 KAP_NTPase PF07693.14 OAG40960.1 - 0.046 12.9 0.1 1.7 7.8 0.1 2.4 1 1 0 2 2 2 0 KAP family P-loop domain AAA_29 PF13555.6 OAG40960.1 - 0.15 11.8 0.0 0.33 10.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATP_transf PF09830.9 OAG40961.1 - 4.1e-22 78.1 0.0 7.7e-22 77.2 0.0 1.5 1 0 0 1 1 1 1 ATP adenylyltransferase DUF4931 PF16285.5 OAG40961.1 - 0.14 11.4 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4931) zf-C2H2 PF00096.26 OAG40962.1 - 0.00016 21.9 20.2 0.35 11.4 1.7 5.1 5 0 0 5 5 4 4 Zinc finger, C2H2 type zf-met PF12874.7 OAG40962.1 - 0.033 14.6 1.5 2 8.9 0.6 3.1 2 0 0 2 2 2 0 Zinc-finger of C2H2 type CNDH2_C PF16858.5 OAG40962.1 - 0.035 14.0 3.2 0.058 13.3 3.2 1.3 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term CDC45 PF02724.14 OAG40962.1 - 0.093 11.0 2.5 0.13 10.6 2.5 1.1 1 0 0 1 1 1 0 CDC45-like protein zf-C2H2_4 PF13894.6 OAG40962.1 - 0.18 12.7 20.5 0.49 11.4 0.7 5.3 5 1 0 5 5 4 0 C2H2-type zinc finger TT_ORF2 PF02957.15 OAG40962.1 - 0.23 12.4 5.4 0.7 10.8 5.2 2.0 1 1 0 1 1 1 0 TT viral ORF2 Tub_N PF16322.5 OAG40962.1 - 0.4 11.1 9.1 0.74 10.2 9.1 1.4 1 0 0 1 1 1 0 Tubby N-terminal DUF4611 PF15387.6 OAG40962.1 - 0.49 10.6 7.5 0.98 9.7 7.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Cwf_Cwc_15 PF04889.12 OAG40962.1 - 0.65 9.7 12.2 2 8.1 10.4 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein zf-C2H2_jaz PF12171.8 OAG40962.1 - 1.2 9.5 8.4 3.3 8.1 0.8 3.5 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding PBP1_TM PF14812.6 OAG40962.1 - 1.2 9.5 8.7 3.9 7.9 8.7 1.9 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal zf-C2H2_2 PF12756.7 OAG40962.1 - 1.5 9.2 4.8 0.38 11.1 0.3 2.4 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) CENP-B_dimeris PF09026.10 OAG40962.1 - 4.1 7.8 17.7 11 6.4 16.6 2.1 2 0 0 2 2 2 0 Centromere protein B dimerisation domain RPN7 PF10602.9 OAG40963.1 - 2e-51 174.2 0.4 3.3e-51 173.4 0.4 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 OAG40963.1 - 1e-11 45.2 0.0 3.6e-11 43.5 0.0 2.0 1 1 0 1 1 1 1 PCI domain Amidohydro_1 PF01979.20 OAG40964.1 - 8.7e-28 97.6 0.3 1.1e-14 54.6 0.0 2.1 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 OAG40964.1 - 3.3e-14 53.2 0.6 5.4e-06 26.1 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family SMP_LBD PF17047.5 OAG40965.1 - 7.3e-29 100.5 0.1 1.2e-28 99.8 0.1 1.3 1 0 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain adh_short PF00106.25 OAG40965.1 - 3.4e-27 95.2 0.2 1.1e-19 70.7 0.0 2.4 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAG40965.1 - 1.3e-21 77.3 0.2 1e-17 64.5 0.0 2.4 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase C2 PF00168.30 OAG40965.1 - 3.8e-17 62.5 0.0 2e-12 47.3 0.0 2.5 2 0 0 2 2 2 2 C2 domain KR PF08659.10 OAG40965.1 - 0.00045 20.2 0.0 0.0011 19.0 0.0 1.6 1 0 0 1 1 1 1 KR domain Herpes_UL92 PF03048.14 OAG40965.1 - 0.17 11.6 0.2 0.31 10.8 0.2 1.3 1 0 0 1 1 1 0 UL92 family GFA PF04828.14 OAG40967.1 - 1.1e-19 70.6 0.2 1.4e-19 70.2 0.2 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme tRNA-synt_2c PF01411.19 OAG40968.1 - 5e-219 728.4 0.0 7.5e-219 727.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 OAG40968.1 - 4e-18 65.2 0.9 9.2e-18 64.1 0.9 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 OAG40968.1 - 1.5e-14 54.6 0.1 4.9e-14 52.9 0.1 2.0 1 0 0 1 1 1 1 DHHA1 domain PolyA_pol_arg_C PF12626.7 OAG40968.1 - 0.041 13.9 0.2 0.081 13.0 0.2 1.4 1 0 0 1 1 1 0 Polymerase A arginine-rich C-terminus PDCD7 PF16021.5 OAG40969.1 - 0.045 12.9 7.7 0.025 13.7 4.7 1.8 2 0 0 2 2 2 0 Programmed cell death protein 7 RCR PF12273.8 OAG40970.1 - 1.3e-14 54.8 9.4 2e-14 54.3 9.4 1.3 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red zf-rbx1 PF12678.7 OAG40971.1 - 2e-10 40.8 2.2 3.6e-10 40.0 2.2 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 OAG40971.1 - 2.3e-07 31.0 8.8 1.6e-06 28.4 8.8 2.1 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 OAG40971.1 - 2.7e-06 27.2 2.4 4.9e-06 26.3 2.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OAG40971.1 - 2.8e-05 23.8 3.5 2.8e-05 23.8 3.5 1.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAG40971.1 - 2.9e-05 24.0 3.3 6.2e-05 22.9 3.3 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Zn_ribbon_17 PF17120.5 OAG40971.1 - 7.1e-05 22.4 0.5 0.00014 21.4 0.5 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 OAG40971.1 - 0.0007 19.4 5.3 0.0017 18.1 1.7 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 OAG40971.1 - 0.0013 18.7 2.9 0.0051 16.8 2.9 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 OAG40971.1 - 0.0014 18.5 3.9 0.0086 16.0 4.4 1.9 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_11 PF17123.5 OAG40971.1 - 0.044 13.5 1.3 0.36 10.6 0.2 2.3 2 0 0 2 2 2 0 RING-like zinc finger Prok-RING_4 PF14447.6 OAG40971.1 - 0.061 13.2 4.1 0.14 12.0 4.1 1.6 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 OAG40971.1 - 0.062 13.5 1.3 0.12 12.6 1.3 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zinc_ribbon_16 PF17034.5 OAG40971.1 - 0.09 13.0 0.3 0.19 12.0 0.3 1.4 1 0 0 1 1 1 0 Zinc-ribbon like family AtuA PF07287.11 OAG40972.1 - 9.1e-124 412.7 0.4 1.2e-123 412.4 0.4 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA SGL PF08450.12 OAG40973.1 - 1.5e-42 145.9 0.0 1.7e-42 145.7 0.0 1.0 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 OAG40973.1 - 0.0014 18.7 0.0 0.042 14.0 0.0 2.8 3 1 0 3 3 3 1 Strictosidine synthase NHL PF01436.21 OAG40973.1 - 0.0015 18.4 0.1 17 5.7 0.0 4.5 5 0 0 5 5 5 2 NHL repeat Arylesterase PF01731.20 OAG40973.1 - 0.0018 18.5 0.0 0.3 11.3 0.0 3.3 3 0 0 3 3 3 1 Arylesterase DUF1513 PF07433.11 OAG40973.1 - 0.041 12.9 0.0 0.065 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1513) Fungal_trans PF04082.18 OAG40974.1 - 7.2e-24 84.2 0.0 1.2e-23 83.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG40974.1 - 1.1e-09 38.3 16.0 2e-09 37.4 16.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 OAG40975.1 - 6e-36 124.1 58.7 6.2e-29 101.0 36.1 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily UPF0182 PF03699.13 OAG40975.1 - 0.0041 15.3 0.3 0.0071 14.5 0.3 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0182) DUF5305 PF17231.2 OAG40975.1 - 0.34 10.3 0.9 2.1 7.7 0.0 2.5 3 0 0 3 3 3 0 Family of unknown function (DUF5305) Claudin_2 PF13903.6 OAG40975.1 - 0.43 10.3 7.4 1.2 8.8 1.5 2.6 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction adh_short_C2 PF13561.6 OAG40976.1 - 2.5e-65 220.3 1.6 3.1e-65 220.0 1.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG40976.1 - 5.9e-51 172.7 0.4 7e-51 172.5 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG40976.1 - 1.2e-11 44.8 0.3 1.9e-11 44.2 0.3 1.2 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 OAG40976.1 - 0.036 13.4 0.1 0.069 12.5 0.1 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ATP_bind_2 PF03668.15 OAG40976.1 - 0.061 12.6 0.7 0.15 11.4 0.2 1.7 1 1 1 2 2 2 0 P-loop ATPase protein family DUF3431 PF11913.8 OAG40977.1 - 3.5e-89 298.2 0.7 4.4e-89 297.9 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) DUF4355 PF14265.6 OAG40977.1 - 5.3 7.3 7.1 4.3 7.6 5.5 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) p450 PF00067.22 OAG40978.1 - 2.1e-27 96.0 0.0 7.8e-27 94.1 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 Cyclase PF04199.13 OAG40978.1 - 1.4e-11 44.8 0.0 3.9e-11 43.3 0.0 1.8 1 0 0 1 1 1 1 Putative cyclase HET PF06985.11 OAG40979.1 - 6.9e-26 91.3 0.0 1.1e-25 90.7 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PAS_9 PF13426.7 OAG40980.1 - 4.3e-07 30.1 0.0 1.8e-05 24.9 0.0 2.6 2 0 0 2 2 2 1 PAS domain Pkinase PF00069.25 OAG40981.1 - 2.6e-06 27.0 0.0 3.3e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 OAG40981.1 - 0.00015 21.2 0.0 0.0002 20.8 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OAG40981.1 - 0.013 15.5 0.0 0.4 10.5 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family DUF1180 PF06679.12 OAG40983.1 - 1.8 8.9 5.0 0.53 10.7 1.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) MFS_1 PF07690.16 OAG40985.1 - 1.2e-17 63.9 34.1 1e-10 41.1 11.2 3.2 3 0 0 3 3 3 3 Major Facilitator Superfamily LacY_symp PF01306.19 OAG40985.1 - 0.029 13.2 7.2 0.084 11.6 2.1 2.9 3 0 0 3 3 3 0 LacY proton/sugar symporter adh_short_C2 PF13561.6 OAG40987.1 - 1.2e-58 198.5 0.9 1.4e-58 198.2 0.9 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG40987.1 - 1.8e-46 158.1 0.9 2.3e-46 157.7 0.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG40987.1 - 1.6e-11 44.4 0.8 2.5e-11 43.8 0.8 1.3 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 OAG40987.1 - 0.0078 15.2 0.1 0.03 13.3 0.0 1.8 1 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 OAG40987.1 - 0.06 12.8 0.3 0.32 10.4 0.3 2.1 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family p450 PF00067.22 OAG40988.1 - 1e-61 209.1 0.0 1.3e-61 208.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.18 OAG40989.1 - 5.8e-15 55.0 0.4 1.1e-14 54.1 0.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG40989.1 - 2.1e-07 30.9 10.4 3.8e-07 30.1 10.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AA_permease PF00324.21 OAG40991.1 - 7.3e-147 489.8 33.6 8.3e-147 489.6 33.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAG40991.1 - 3e-38 131.7 35.6 3.9e-38 131.4 35.6 1.1 1 0 0 1 1 1 1 Amino acid permease Internalin_N PF12354.8 OAG40991.1 - 0.04 14.0 0.2 0.25 11.4 0.0 2.5 2 0 0 2 2 2 0 Bacterial adhesion/invasion protein N terminal Rad4 PF03835.15 OAG40992.1 - 1.2e-15 57.4 4.6 2.3e-15 56.6 4.6 1.4 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Transglut_core PF01841.19 OAG40992.1 - 3.9e-13 49.9 1.3 8.3e-13 48.8 1.3 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily YdjO PF14169.6 OAG40992.1 - 0.008 15.9 0.2 6.2 6.6 0.1 2.5 2 0 0 2 2 2 2 Cold-inducible protein YdjO WD40 PF00400.32 OAG40993.1 - 3.9e-11 43.3 4.0 0.36 11.8 0.2 8.2 9 0 0 9 9 9 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG40993.1 - 5.4e-10 39.4 0.6 0.13 12.6 0.0 6.5 4 2 2 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OAG40993.1 - 0.017 14.1 0.0 0.71 8.8 0.0 3.0 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Rhabdo_glycop PF00974.18 OAG40993.1 - 0.043 12.3 0.0 0.076 11.5 0.0 1.3 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein PD40 PF07676.12 OAG40993.1 - 0.11 12.5 0.4 0.9 9.6 0.0 2.7 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Fungal_trans_2 PF11951.8 OAG40994.1 - 7.1e-10 38.2 0.4 2.8e-09 36.3 0.4 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Fer2_2 PF01799.20 OAG40994.1 - 0.15 12.1 0.3 0.36 10.9 0.3 1.7 1 0 0 1 1 1 0 [2Fe-2S] binding domain PBP PF01161.20 OAG40996.1 - 2.7e-17 63.3 0.0 3.5e-17 63.0 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Pkinase PF00069.25 OAG40997.1 - 4e-26 92.0 0.0 7.7e-25 87.7 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG40997.1 - 3e-09 36.5 0.0 2.9e-05 23.5 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase RIO1 PF01163.22 OAG40997.1 - 0.083 12.5 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 RIO1 family adh_short PF00106.25 OAG40998.1 - 7.2e-35 120.2 0.1 9.7e-35 119.8 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG40998.1 - 5.2e-25 88.4 0.0 9.3e-25 87.5 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG40998.1 - 4.1e-08 33.3 0.1 6e-08 32.8 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG40998.1 - 5.8e-05 22.7 0.4 0.0011 18.4 0.4 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 OAG40998.1 - 0.034 13.3 0.1 0.069 12.3 0.1 1.5 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.8 OAG40998.1 - 0.039 13.7 0.8 0.079 12.7 0.8 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Shikimate_DH PF01488.20 OAG40998.1 - 0.045 13.8 0.1 0.074 13.1 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Glyco_hydro_3_C PF01915.22 OAG40998.1 - 0.072 13.0 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain Fungal_trans PF04082.18 OAG40999.1 - 3.4e-13 49.3 0.0 4.6e-13 48.8 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG40999.1 - 1.8e-07 31.2 8.8 3.1e-07 30.4 8.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain YopE_N PF09020.10 OAG40999.1 - 0.0057 16.9 0.0 0.011 16.0 0.0 1.4 1 0 0 1 1 1 1 YopE, N terminal Lar_restr_allev PF14354.6 OAG40999.1 - 0.12 12.7 2.0 0.25 11.8 2.0 1.4 1 0 0 1 1 1 0 Restriction alleviation protein Lar EndIII_4Fe-2S PF10576.9 OAG40999.1 - 0.26 11.7 3.6 0.61 10.5 3.6 1.7 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III SOBP PF15279.6 OAG40999.1 - 0.76 10.3 2.9 0.29 11.7 0.6 1.5 2 0 0 2 2 2 0 Sine oculis-binding protein GST_N_3 PF13417.6 OAG41000.1 - 4.6e-09 36.5 0.1 9.3e-09 35.6 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OAG41000.1 - 6.5e-07 29.6 0.0 2.2e-06 27.9 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 OAG41000.1 - 0.00026 21.3 0.0 0.00061 20.1 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAG41000.1 - 0.00062 19.7 0.1 0.0015 18.5 0.1 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain SUIM_assoc PF16619.5 OAG41000.1 - 0.0056 16.7 0.0 1.6 8.8 4.3 2.3 2 1 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 GST_C_6 PF17171.4 OAG41000.1 - 0.07 12.9 0.0 0.3 10.9 0.0 2.1 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain TauD PF02668.16 OAG41001.1 - 4e-47 161.3 0.1 4.5e-47 161.1 0.1 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF2235 PF09994.9 OAG41002.1 - 2.9e-34 118.7 0.0 4.4e-34 118.1 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Sugar_tr PF00083.24 OAG41003.1 - 2e-76 257.7 15.2 2.3e-76 257.5 15.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG41003.1 - 6.9e-27 94.3 29.6 5.5e-25 88.0 15.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 OAG41003.1 - 1.6e-08 33.4 2.4 3.5e-08 32.3 2.4 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.6 OAG41003.1 - 1.3e-05 23.9 5.8 1.3e-05 23.9 5.8 2.8 2 2 0 2 2 2 1 MFS/sugar transport protein Cellulase PF00150.18 OAG41004.1 - 1.8e-27 96.5 0.3 2.9e-27 95.8 0.3 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Trypsin_2 PF13365.6 OAG41005.1 - 0.0033 18.3 0.1 0.021 15.8 0.0 2.2 2 1 0 2 2 2 1 Trypsin-like peptidase domain Fungal_trans PF04082.18 OAG41006.1 - 2.9e-09 36.3 0.0 5.2e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain p450 PF00067.22 OAG41007.1 - 1.3e-74 251.6 0.0 1.5e-74 251.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Flavin_Reduct PF01613.18 OAG41008.1 - 1.5e-15 57.6 0.0 2.1e-15 57.1 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain DUF447 PF04289.12 OAG41008.1 - 0.0056 16.5 0.1 0.0093 15.8 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF447) FAA_hydrolase PF01557.18 OAG41009.1 - 7.3e-50 169.6 0.0 1e-49 169.2 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 OAG41009.1 - 1.6e-26 92.5 0.0 2.7e-26 91.9 0.0 1.3 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal HgmA PF04209.13 OAG41010.1 - 4.9e-170 565.8 0.0 5.7e-170 565.6 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase DUF1445 PF07286.12 OAG41011.1 - 1.4e-60 203.4 0.0 2.4e-60 202.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1445) EthD PF07110.11 OAG41012.1 - 0.0044 18.1 0.0 0.0074 17.4 0.0 1.4 1 1 0 1 1 1 1 EthD domain SLX9 PF15341.6 OAG41013.1 - 2.2e-34 118.7 1.5 2.2e-34 118.7 1.5 1.7 2 0 0 2 2 2 1 Ribosome biogenesis protein SLX9 Aldo_ket_red PF00248.21 OAG41014.1 - 1e-32 113.5 0.0 1.2e-32 113.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family NmrA PF05368.13 OAG41015.1 - 8.1e-16 58.3 0.0 1.1e-15 57.8 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG41015.1 - 9.2e-08 32.2 0.0 1.6e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 OAG41015.1 - 0.013 15.7 0.1 0.026 14.8 0.0 1.5 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain adh_short PF00106.25 OAG41016.1 - 2.2e-39 135.0 0.7 2.8e-39 134.6 0.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG41016.1 - 1.1e-31 110.3 0.2 1.3e-31 110.0 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG41016.1 - 1.2e-15 57.9 0.6 1.6e-15 57.5 0.6 1.1 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.8 OAG41016.1 - 0.002 17.9 0.1 0.06 13.1 0.1 2.4 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Polysacc_synt_2 PF02719.15 OAG41016.1 - 0.0039 16.4 0.1 0.0043 16.2 0.1 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein FAM25 PF15825.5 OAG41016.1 - 0.045 14.1 2.4 0.087 13.2 2.4 1.5 1 0 0 1 1 1 0 FAM25 family Epimerase PF01370.21 OAG41016.1 - 0.073 12.5 0.4 0.096 12.1 0.4 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family p450 PF00067.22 OAG41018.1 - 1.3e-68 231.9 0.0 1.6e-68 231.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 His_Phos_2 PF00328.22 OAG41020.1 - 3.3e-27 95.8 0.0 4.3e-27 95.5 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Transp_cyt_pur PF02133.15 OAG41021.1 - 1.2e-97 327.5 36.8 1.4e-97 327.3 36.8 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin PET10 PF17316.2 OAG41022.1 - 0.066 12.7 0.3 0.24 10.9 0.0 1.9 1 1 1 2 2 2 0 Petite colonies protein 10 PARP PF00644.20 OAG41023.1 - 6.1e-10 39.0 0.0 1.3e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain UQ_con PF00179.26 OAG41023.1 - 7.9e-08 32.1 0.0 1.9e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Peptidase_M75 PF09375.10 OAG41024.1 - 0.071 12.6 0.0 0.64 9.4 0.0 2.1 2 1 0 2 2 2 0 Imelysin Ribosomal_L27e PF01777.18 OAG41025.1 - 4.9e-38 129.3 4.8 7.5e-38 128.8 4.8 1.3 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 OAG41025.1 - 0.0054 16.6 0.4 0.014 15.4 0.4 1.7 1 0 0 1 1 1 1 KOW motif UBA_2 PF08587.11 OAG41026.1 - 0.0014 18.7 4.0 15 5.8 0.0 6.4 6 0 0 6 6 6 2 Ubiquitin associated domain (UBA) Ntox1 PF15500.6 OAG41026.1 - 0.48 10.8 2.5 9.3 6.7 0.1 4.1 3 0 0 3 3 3 0 Putative RNase-like toxin, toxin_1 GPS2_interact PF15784.5 OAG41026.1 - 1.1 9.8 12.2 4.7 7.7 0.4 4.6 4 0 0 4 4 4 0 G-protein pathway suppressor 2-interacting domain CMD PF02627.20 OAG41026.1 - 1.3 9.2 3.8 2.8 8.1 0.1 3.6 4 0 0 4 4 4 0 Carboxymuconolactone decarboxylase family TRAM_LAG1_CLN8 PF03798.16 OAG41027.1 - 8.9e-52 175.7 8.7 1.2e-51 175.3 8.7 1.1 1 0 0 1 1 1 1 TLC domain Mo25 PF08569.11 OAG41028.1 - 1.8e-123 412.1 0.0 2.1e-123 411.9 0.0 1.0 1 0 0 1 1 1 1 Mo25-like Ndc80_HEC PF03801.13 OAG41029.1 - 5.1e-59 198.3 0.1 9.6e-59 197.4 0.1 1.5 1 0 0 1 1 1 1 HEC/Ndc80p family Filament PF00038.21 OAG41029.1 - 0.00019 21.2 40.1 0.0065 16.1 24.2 2.5 2 0 0 2 2 2 2 Intermediate filament protein DUF3584 PF12128.8 OAG41029.1 - 0.00048 17.8 6.4 0.00048 17.8 6.4 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3584) LXG PF04740.12 OAG41029.1 - 0.0025 17.5 2.2 0.0025 17.5 2.2 3.2 2 1 2 4 4 4 1 LXG domain of WXG superfamily Syntaxin_2 PF14523.6 OAG41029.1 - 0.013 15.9 17.4 0.2 12.0 6.7 2.9 2 0 0 2 2 2 0 Syntaxin-like protein Nucleoporin_FG PF13634.6 OAG41029.1 - 0.18 12.7 5.3 0.45 11.4 5.3 1.6 1 0 0 1 1 1 0 Nucleoporin FG repeat region CENP-F_leu_zip PF10473.9 OAG41029.1 - 0.41 10.7 43.8 0.25 11.4 19.8 4.0 2 2 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2353 PF09789.9 OAG41029.1 - 1.5 8.2 28.9 0.34 10.2 15.3 2.3 2 0 0 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) NPV_P10 PF05531.12 OAG41029.1 - 1.8 9.1 12.9 40 4.8 0.0 4.5 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.12 OAG41029.1 - 3 7.9 19.9 0.49 10.4 4.4 4.0 2 2 2 4 4 4 0 Protein of unknown function (DUF1664) TMPIT PF07851.13 OAG41029.1 - 4.5 6.4 19.6 3.8 6.7 7.6 2.7 2 1 1 3 3 3 0 TMPIT-like protein Csm1_N PF18504.1 OAG41029.1 - 6.8 7.1 21.3 8.7 6.8 0.5 4.7 2 2 2 4 4 4 0 Csm1 N-terminal domain Pex14_N PF04695.13 OAG41030.1 - 3.3e-40 138.3 0.1 3.3e-40 138.3 0.1 3.6 2 1 0 2 2 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region OmpH PF03938.14 OAG41030.1 - 0.012 15.9 2.1 0.012 15.9 2.1 2.2 2 1 1 3 3 3 0 Outer membrane protein (OmpH-like) Golgin_A5 PF09787.9 OAG41030.1 - 0.016 14.7 3.4 0.024 14.1 3.4 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF1043 PF06295.12 OAG41030.1 - 0.023 14.7 1.3 0.023 14.7 1.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) FlgN PF05130.12 OAG41030.1 - 0.028 14.9 8.6 0.045 14.3 8.6 1.3 1 0 0 1 1 1 0 FlgN protein Baculo_PEP_C PF04513.12 OAG41030.1 - 0.029 14.4 3.3 0.088 12.8 3.3 1.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus CR6_interact PF10147.9 OAG41030.1 - 0.031 14.0 0.0 0.047 13.4 0.0 1.2 1 0 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 DUF3584 PF12128.8 OAG41030.1 - 0.058 10.9 9.2 0.08 10.4 9.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Rsd_AlgQ PF04353.13 OAG41030.1 - 0.1 12.5 0.6 0.18 11.7 0.4 1.5 1 1 0 1 1 1 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ zf-C4H2 PF10146.9 OAG41030.1 - 0.11 12.8 6.8 0.46 10.8 6.8 2.1 1 1 0 1 1 1 0 Zinc finger-containing protein XhlA PF10779.9 OAG41030.1 - 0.15 12.2 5.8 4.1 7.7 0.3 2.7 2 0 0 2 2 2 0 Haemolysin XhlA Myosin_tail_1 PF01576.19 OAG41030.1 - 0.19 9.5 9.1 0.63 7.8 9.4 1.5 1 1 0 1 1 1 0 Myosin tail FAM76 PF16046.5 OAG41030.1 - 0.42 9.9 2.4 0.69 9.2 2.4 1.3 1 0 0 1 1 1 0 FAM76 protein AAA_13 PF13166.6 OAG41030.1 - 0.73 8.4 4.3 0.99 8.0 4.3 1.1 1 0 0 1 1 1 0 AAA domain Csm1_N PF18504.1 OAG41030.1 - 1.4 9.3 4.9 2.1 8.8 3.2 2.2 1 1 0 1 1 1 0 Csm1 N-terminal domain CLZ PF16526.5 OAG41030.1 - 2.1 8.7 7.0 13 6.3 0.6 2.7 2 1 1 3 3 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF4404 PF14357.6 OAG41030.1 - 4 8.2 8.0 1.6 9.4 4.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) AAA_23 PF13476.6 OAG41031.1 - 0.49 10.9 8.6 0.7 10.4 8.6 1.3 1 0 0 1 1 1 0 AAA domain TTL PF03133.15 OAG41032.1 - 3e-54 184.2 0.0 4.6e-54 183.5 0.0 1.3 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family SurE PF01975.17 OAG41032.1 - 7.2e-36 123.8 0.0 1.1e-35 123.2 0.0 1.3 1 0 0 1 1 1 1 Survival protein SurE ATPgrasp_YheCD PF14398.6 OAG41032.1 - 5.6e-05 22.5 0.0 0.00052 19.3 0.0 2.1 2 0 0 2 2 2 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 OAG41032.1 - 0.06 12.6 0.0 0.2 10.9 0.0 1.7 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp ABC_membrane PF00664.23 OAG41033.1 - 3.5e-19 69.5 5.7 5.2e-19 68.9 5.7 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 OAG41033.1 - 1.2e-13 51.8 0.0 3.4e-13 50.3 0.0 1.8 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 OAG41033.1 - 0.027 13.9 0.0 0.032 13.7 0.0 1.2 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain NiFe_hyd_3_EhaA PF17367.2 OAG41033.1 - 0.16 12.2 2.0 0.29 11.3 0.4 2.1 2 0 0 2 2 2 0 NiFe-hydrogenase-type-3 Eha complex subunit A MFS_1 PF07690.16 OAG41034.1 - 4.8e-22 78.4 47.6 2.3e-15 56.4 19.4 2.0 1 1 0 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.25 OAG41037.1 - 1.3e-68 231.3 0.0 1.7e-68 230.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG41037.1 - 3.9e-32 111.5 0.0 7.6e-32 110.6 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAG41037.1 - 0.00025 20.5 0.0 0.0018 17.7 0.0 2.2 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 OAG41037.1 - 0.0017 17.8 0.0 0.0028 17.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OAG41037.1 - 0.0023 17.9 0.1 0.026 14.5 0.0 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OAG41037.1 - 0.029 13.3 0.0 0.048 12.6 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain FTA2 PF13095.6 OAG41037.1 - 0.038 13.6 0.0 10 5.7 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 PH_3 PF14593.6 OAG41037.1 - 0.16 12.1 0.0 0.46 10.6 0.0 1.8 1 0 0 1 1 1 0 PH domain MFS_1 PF07690.16 OAG41039.1 - 7.4e-40 136.9 30.5 2.2e-39 135.4 22.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG41039.1 - 2.9e-10 39.6 3.6 2.9e-10 39.6 3.6 2.8 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 OAG41039.1 - 2.6e-08 32.8 2.3 3.8e-08 32.2 2.3 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF3482 PF11981.8 OAG41039.1 - 0.3 10.4 0.3 0.62 9.4 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) Fungal_trans PF04082.18 OAG41040.1 - 1.6e-24 86.4 0.1 2.9e-24 85.5 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG41040.1 - 2.5e-07 30.7 10.9 4.6e-07 29.8 10.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.25 OAG41041.1 - 1.1e-40 139.3 0.1 1.5e-40 138.8 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG41041.1 - 3.6e-25 88.9 0.8 7.8e-25 87.8 0.4 1.6 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG41041.1 - 1.2e-06 28.6 0.2 1.7e-06 28.1 0.2 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 OAG41041.1 - 5.4e-05 23.2 0.0 8.2e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding DUF1776 PF08643.10 OAG41041.1 - 0.0036 16.7 0.0 0.0047 16.3 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) ADH_zinc_N PF00107.26 OAG41041.1 - 0.0087 16.0 0.3 0.021 14.8 0.1 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase MgtC PF02308.16 OAG41043.1 - 0.0074 16.6 3.3 0.013 15.8 3.3 1.4 1 0 0 1 1 1 1 MgtC family Phage_TAC_8 PF10666.9 OAG41043.1 - 0.019 15.3 0.1 0.073 13.3 0.0 1.9 2 1 0 2 2 2 0 Phage tail assembly chaperone protein Gp14 ()A118 DUF3278 PF11683.8 OAG41043.1 - 0.022 14.8 1.6 0.043 13.9 1.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3278) Tmpp129 PF10272.9 OAG41043.1 - 0.09 12.1 1.1 0.13 11.5 1.1 1.2 1 0 0 1 1 1 0 Putative transmembrane protein precursor Peptidase_U4 PF03419.13 OAG41043.1 - 7.5 5.7 8.5 11 5.2 8.5 1.2 1 0 0 1 1 1 0 Sporulation factor SpoIIGA Asp_protease_2 PF13650.6 OAG41044.1 - 9e-06 26.2 0.0 2e-05 25.1 0.0 1.6 1 1 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 OAG41044.1 - 0.0016 18.9 0.0 0.0033 18.0 0.0 1.6 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 OAG41044.1 - 0.026 14.9 0.0 0.042 14.2 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease adh_short_C2 PF13561.6 OAG41046.1 - 1.5e-58 198.1 0.1 1.9e-58 197.8 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG41046.1 - 1.6e-47 161.5 0.3 2e-47 161.2 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG41046.1 - 6.2e-13 49.0 0.1 9.4e-13 48.5 0.1 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 OAG41046.1 - 0.045 13.1 0.0 0.071 12.5 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) adh_short PF00106.25 OAG41047.1 - 3.6e-34 118.0 0.0 4.6e-34 117.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG41047.1 - 2.9e-28 99.0 0.1 4.5e-28 98.4 0.1 1.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG41047.1 - 1.9e-13 50.8 0.1 2.8e-13 50.2 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG41047.1 - 8.6e-07 28.7 0.0 1.4e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family YjeF_N PF03853.15 OAG41047.1 - 0.097 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 YjeF-related protein N-terminus DUF3425 PF11905.8 OAG41048.1 - 1.8e-12 47.3 1.2 1.2e-11 44.7 1.2 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_Maf PF03131.17 OAG41048.1 - 2.2 8.8 9.6 4.1 8.0 9.6 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor Peptidase_S24 PF00717.23 OAG41049.1 - 3.2e-08 33.4 0.0 5e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like DUF3433 PF11915.8 OAG41050.1 - 3.3e-36 123.6 21.9 8.2e-20 71.1 2.9 4.2 4 0 0 4 4 4 2 Protein of unknown function (DUF3433) DUF3292 PF11696.8 OAG41051.1 - 1.7e-263 875.8 0.0 7e-261 867.2 0.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3292) PRT_C PF08372.10 OAG41051.1 - 0.00024 20.9 0.2 0.00061 19.6 0.2 1.6 2 0 0 2 2 2 1 Plant phosphoribosyltransferase C-terminal adh_short PF00106.25 OAG41052.1 - 1.4e-18 67.0 0.0 3e-16 59.5 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAG41052.1 - 1.2e-09 38.1 0.0 3.4e-09 36.6 0.0 1.6 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG41052.1 - 0.00035 20.5 0.0 0.00056 19.9 0.0 1.3 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 OAG41052.1 - 0.011 15.2 0.1 0.45 9.9 0.0 2.1 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase LuxQ-periplasm PF09308.10 OAG41052.1 - 0.045 13.2 0.1 0.069 12.6 0.1 1.2 1 0 0 1 1 1 0 LuxQ, periplasmic Shikimate_DH PF01488.20 OAG41052.1 - 0.21 11.7 0.0 0.28 11.2 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Lactamase_B_2 PF12706.7 OAG41053.1 - 3e-33 115.0 0.0 1.2e-32 113.0 0.0 1.9 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 OAG41053.1 - 7.2e-13 48.7 0.0 1.2e-12 48.0 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 OAG41053.1 - 0.026 14.5 1.3 0.19 11.7 0.0 2.5 3 0 0 3 3 3 0 Metallo-beta-lactamase superfamily Amidohydro_2 PF04909.14 OAG41054.1 - 4.2e-44 151.5 0.0 4.8e-44 151.3 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase DOG1 PF14144.6 OAG41054.1 - 0.096 12.9 0.0 0.26 11.5 0.0 1.8 1 0 0 1 1 1 0 Seed dormancy control CorA PF01544.18 OAG41056.1 - 3.1e-08 33.3 1.3 3.3e-07 29.9 0.2 2.3 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein BatD PF13584.6 OAG41056.1 - 0.059 12.2 0.1 0.087 11.6 0.1 1.2 1 0 0 1 1 1 0 Oxygen tolerance DUF3792 PF12670.7 OAG41057.1 - 1.5 9.0 7.2 2.2 8.5 7.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3792) RNA_pol_Rpc4 PF05132.14 OAG41058.1 - 0.17 12.3 1.9 0.22 12.0 1.9 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 GMC_oxred_N PF00732.19 OAG41059.1 - 7.6e-49 166.7 0.0 1.2e-48 166.0 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAG41059.1 - 2.9e-31 108.9 0.2 4.6e-31 108.3 0.2 1.3 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 OAG41059.1 - 4.9e-05 23.5 0.0 0.00015 22.0 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAG41059.1 - 0.00092 18.9 0.1 0.0083 15.7 0.0 2.3 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG41059.1 - 0.0016 17.7 0.0 0.052 12.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG41059.1 - 0.019 14.2 0.0 5.1 6.3 0.0 2.4 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OAG41059.1 - 0.032 13.3 0.0 0.067 12.2 0.0 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein SLATT_fungal PF18142.1 OAG41060.1 - 2.3e-30 105.0 0.2 2.9e-30 104.7 0.2 1.1 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain SLATT_1 PF18181.1 OAG41060.1 - 0.07 13.1 0.9 0.1 12.5 0.9 1.3 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 1 SLATT_3 PF18184.1 OAG41060.1 - 0.15 12.2 1.0 0.2 11.8 0.5 1.5 1 1 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 3 NmrA PF05368.13 OAG41061.1 - 1.1e-55 188.8 0.8 1.4e-55 188.4 0.8 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG41061.1 - 9.1e-15 55.0 2.2 1.5e-14 54.3 2.2 1.3 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 OAG41061.1 - 2.6e-05 23.4 0.0 3.7e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 OAG41061.1 - 0.0018 17.8 0.1 0.0034 16.9 0.1 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 OAG41061.1 - 0.0028 17.9 0.2 0.0099 16.1 0.2 1.9 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Kinesin PF00225.23 OAG41062.1 - 2.7e-58 197.5 0.0 4.1e-58 196.9 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 OAG41062.1 - 7.1e-12 45.5 0.1 6.1e-10 39.2 0.0 2.4 2 0 0 2 2 2 1 Microtubule binding DUF1640 PF07798.11 OAG41062.1 - 0.011 15.8 4.2 0.045 13.8 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) Peptidase_C58 PF03543.14 OAG41062.1 - 0.085 12.5 0.1 0.77 9.4 0.0 2.3 2 1 0 2 2 2 0 Yersinia/Haemophilus virulence surface antigen Cnn_1N PF07989.11 OAG41062.1 - 0.12 12.5 0.2 0.12 12.5 0.2 2.1 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 DUF87 PF01935.17 OAG41062.1 - 1.7 8.6 4.8 7.4 6.6 0.7 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain T2SSM PF04612.12 OAG41062.1 - 4.2 7.4 6.2 0.25 11.4 0.4 1.9 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M Acetyltransf_2 PF00797.17 OAG41063.1 - 3.9e-36 125.1 0.0 5.3e-36 124.6 0.0 1.2 1 0 0 1 1 1 1 N-acetyltransferase adh_short PF00106.25 OAG41064.1 - 5.5e-09 35.8 0.0 3.5e-06 26.6 0.0 2.3 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAG41064.1 - 2.2e-08 34.0 0.0 0.0014 18.2 0.0 2.3 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Band_7 PF01145.25 OAG41065.1 - 3.2e-28 98.9 2.6 7.1e-28 97.8 2.6 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 OAG41065.1 - 0.035 13.8 0.1 0.067 12.9 0.1 1.5 1 0 0 1 1 1 0 SPFH domain-Band 7 family adh_short PF00106.25 OAG41066.1 - 1.6e-28 99.5 0.0 8.1e-27 94.0 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG41066.1 - 5.2e-18 65.5 0.0 4.8e-17 62.3 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG41066.1 - 5.9e-06 26.3 0.1 9.5e-06 25.6 0.1 1.3 1 0 0 1 1 1 1 KR domain DUF3657 PF12394.8 OAG41066.1 - 0.058 14.0 0.0 0.24 12.0 0.0 2.0 2 0 0 2 2 2 0 Protein FAM135 Shikimate_DH PF01488.20 OAG41066.1 - 0.13 12.4 0.1 0.21 11.6 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase zf-CSL PF05207.13 OAG41066.1 - 0.13 12.0 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 CSL zinc finger p450 PF00067.22 OAG41067.1 - 1.8e-52 178.7 0.0 2.7e-52 178.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 UQ_con PF00179.26 OAG41067.1 - 2.4e-21 75.8 0.0 4.2e-21 75.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme EAF PF09816.9 OAG41068.1 - 6.1e-14 52.2 0.0 1.4e-13 51.1 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor DUF726 PF05277.12 OAG41069.1 - 3.7e-116 387.8 1.8 5e-116 387.4 1.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Thioesterase PF00975.20 OAG41069.1 - 0.044 13.9 0.7 0.095 12.8 0.0 1.8 2 0 0 2 2 2 0 Thioesterase domain CD225 PF04505.12 OAG41069.1 - 3.8 7.7 5.4 1.1 9.5 1.1 2.2 2 0 0 2 2 2 0 Interferon-induced transmembrane protein SVIP PF15811.5 OAG41069.1 - 4.5 7.8 6.3 45 4.6 1.1 2.9 2 0 0 2 2 2 0 Small VCP/p97-interacting protein Rav1p_C PF12234.8 OAG41070.1 - 5e-198 659.5 0.1 6.5e-198 659.1 0.1 1.1 1 0 0 1 1 1 1 RAVE protein 1 C terminal WD40 PF00400.32 OAG41070.1 - 0.00088 20.0 13.5 1.9 9.5 0.0 6.8 8 0 0 8 8 8 3 WD domain, G-beta repeat Peptidase_C12 PF01088.21 OAG41071.1 - 1.6e-46 158.7 0.0 1.9e-46 158.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Glyoxalase PF00903.25 OAG41071.1 - 0.064 13.4 0.0 0.08 13.1 0.0 1.3 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily PhyH PF05721.13 OAG41072.1 - 1.2e-19 71.5 0.2 2.5e-19 70.4 0.2 1.4 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Glyco_trans_1_4 PF13692.6 OAG41073.1 - 3.7e-08 33.9 0.0 0.0011 19.4 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_56 PF07429.11 OAG41073.1 - 0.13 11.3 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 4-alpha-L-fucosyltransferase glycosyl transferase group 56 Glycos_transf_1 PF00534.20 OAG41073.1 - 0.17 11.4 0.0 0.99 8.9 0.0 2.0 2 0 0 2 2 2 0 Glycosyl transferases group 1 Cation_efflux PF01545.21 OAG41074.1 - 4.5e-44 150.6 4.8 6.2e-44 150.1 4.8 1.2 1 0 0 1 1 1 1 Cation efflux family MFS_3 PF05977.13 OAG41074.1 - 0.063 11.7 0.1 0.11 10.8 0.1 1.3 1 0 0 1 1 1 0 Transmembrane secretion effector SKG6 PF08693.10 OAG41076.1 - 0.0023 17.3 0.9 0.0054 16.1 0.9 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain CcmD PF04995.14 OAG41076.1 - 0.15 12.1 1.0 0.41 10.8 1.0 1.7 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) AA_permease_2 PF13520.6 OAG41077.1 - 1.9e-46 158.8 46.7 2.4e-46 158.4 46.7 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAG41077.1 - 7.6e-24 84.1 40.1 1e-23 83.7 40.1 1.1 1 0 0 1 1 1 1 Amino acid permease p450 PF00067.22 OAG41078.1 - 1.5e-53 182.2 0.0 4.8e-53 180.5 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 TFIIIC_delta PF12657.7 OAG41079.1 - 7.9e-28 97.6 1.7 1.4e-27 96.9 1.7 1.4 1 0 0 1 1 1 1 Transcription factor IIIC subunit delta N-term zf-TFIIIC PF12660.7 OAG41079.1 - 2.5e-22 78.7 0.3 5.9e-22 77.5 0.3 1.6 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex zf_UBZ PF18439.1 OAG41079.1 - 0.25 11.0 0.6 6.9 6.4 0.1 2.6 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger DZR PF12773.7 OAG41079.1 - 0.28 11.2 2.7 3.6 7.7 2.7 2.4 1 1 0 1 1 1 0 Double zinc ribbon zinc_ribbon_9 PF14369.6 OAG41079.1 - 1.2 9.4 4.4 11 6.3 0.4 2.7 2 0 0 2 2 2 0 zinc-ribbon zf-ribbon_3 PF13248.6 OAG41079.1 - 5.4 6.6 7.4 19 4.8 0.3 3.1 3 0 0 3 3 3 0 zinc-ribbon domain Fungal_trans PF04082.18 OAG41082.1 - 3.2e-27 95.2 0.0 1.3e-26 93.2 0.0 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG41082.1 - 7.2e-07 29.2 10.6 1.6e-06 28.1 10.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cellulase PF00150.18 OAG41083.1 - 6e-28 98.1 1.8 2.3e-27 96.1 1.3 1.9 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) COesterase PF00135.28 OAG41084.1 - 1.4e-72 245.2 0.1 3e-72 244.2 0.1 1.4 1 1 0 1 1 1 1 Carboxylesterase family Glyco_hydro_10 PF00331.20 OAG41084.1 - 3.7e-71 239.9 0.0 6e-71 239.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Abhydrolase_3 PF07859.13 OAG41084.1 - 3.6e-09 36.8 0.0 1.7e-08 34.6 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Sugar_tr PF00083.24 OAG41085.1 - 1.5e-88 297.6 21.1 1.9e-88 297.3 21.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG41085.1 - 2.1e-29 102.5 20.6 1.7e-28 99.6 17.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 OAG41085.1 - 1.8e-07 30.0 3.2 3.3e-07 29.1 3.2 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) TMEM141 PF15110.6 OAG41085.1 - 0.14 12.8 0.5 0.49 11.0 0.5 2.0 1 0 0 1 1 1 0 TMEM141 protein family PTR2 PF00854.21 OAG41085.1 - 1.4 7.6 14.1 0.59 8.9 2.6 2.5 2 0 0 2 2 2 0 POT family DEAD PF00270.29 OAG41086.1 - 1.7e-47 161.5 0.0 2.6e-47 160.8 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAG41086.1 - 8.9e-32 109.7 0.1 1.3e-30 106.0 0.1 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG41086.1 - 3.5e-05 23.9 0.0 0.00011 22.3 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 OAG41086.1 - 8e-05 22.0 0.1 0.00014 21.1 0.1 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Flavi_DEAD PF07652.14 OAG41086.1 - 0.018 15.0 0.0 0.06 13.3 0.0 1.8 2 0 0 2 2 2 0 Flavivirus DEAD domain XAP5 PF04921.14 OAG41086.1 - 0.31 10.8 1.5 6 6.6 0.9 2.1 2 0 0 2 2 2 0 XAP5, circadian clock regulator AMP-binding PF00501.28 OAG41087.1 - 5.5e-75 252.5 0.0 7.9e-75 252.0 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 OAG41087.1 - 5.5e-63 212.5 0.0 1e-62 211.6 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein adh_short PF00106.25 OAG41087.1 - 1.4e-52 178.0 1.1 2.6e-52 177.1 1.1 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG41087.1 - 4.1e-39 134.5 2.3 4.6e-39 134.4 1.0 1.7 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG41087.1 - 2.4e-17 63.4 1.1 1e-14 54.9 0.8 2.5 2 0 0 2 2 2 2 KR domain Epimerase PF01370.21 OAG41087.1 - 1.8e-15 57.1 0.0 4e-09 36.3 0.0 3.3 3 1 0 3 3 3 2 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 OAG41087.1 - 3.6e-11 43.2 0.0 9.2e-11 41.9 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site RmlD_sub_bind PF04321.17 OAG41087.1 - 1.5e-07 30.8 0.3 0.0017 17.5 0.0 3.0 3 0 0 3 3 3 2 RmlD substrate binding domain 3Beta_HSD PF01073.19 OAG41087.1 - 1.7e-07 30.6 0.1 7.1e-05 21.9 0.0 3.0 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 OAG41087.1 - 0.00023 20.4 0.5 0.1 11.7 0.1 3.0 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein AMP-binding_C PF13193.6 OAG41087.1 - 0.001 20.0 1.3 0.0059 17.6 0.2 3.0 3 0 0 3 3 2 1 AMP-binding enzyme C-terminal domain GDP_Man_Dehyd PF16363.5 OAG41087.1 - 0.0029 17.1 0.0 2.4 7.5 0.0 2.4 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase DUF4948 PF16306.5 OAG41087.1 - 0.074 12.8 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4948) NmrA PF05368.13 OAG41087.1 - 0.11 12.1 1.7 1.7 8.1 2.0 2.7 4 0 0 4 4 4 0 NmrA-like family Cpn60_TCP1 PF00118.24 OAG41088.1 - 8.9e-167 555.6 3.9 1e-166 555.4 3.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family BRK PF07533.16 OAG41088.1 - 0.18 11.5 0.1 0.36 10.5 0.1 1.5 1 0 0 1 1 1 0 BRK domain DUF2268 PF10026.9 OAG41090.1 - 0.00025 20.7 0.0 0.00042 19.9 0.0 1.3 1 0 0 1 1 1 1 Predicted Zn-dependent protease (DUF2268) Cohesin PF00963.18 OAG41090.1 - 0.00077 19.7 1.2 0.0026 18.0 1.2 1.9 1 0 0 1 1 1 1 Cohesin domain Peptidase_M9 PF01752.17 OAG41090.1 - 0.0018 17.6 0.0 0.003 16.9 0.0 1.2 1 0 0 1 1 1 1 Collagenase Alpha-amylase PF00128.24 OAG41091.1 - 2.3e-112 375.9 0.2 4.1e-112 375.1 0.2 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.6 OAG41091.1 - 0.021 13.9 0.1 0.036 13.2 0.1 1.2 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain Sigma_reg_N PF13800.6 OAG41092.1 - 0.0048 17.1 0.1 0.019 15.3 0.0 2.0 2 0 0 2 2 2 1 Sigma factor regulator N-terminal Phage_holin_3_6 PF07332.11 OAG41092.1 - 0.03 14.4 3.3 0.096 12.7 0.2 2.4 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III DUF3810 PF12725.7 OAG41092.1 - 0.048 13.0 0.0 0.075 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) CbiM PF01891.16 OAG41092.1 - 0.051 13.4 0.1 0.051 13.4 0.1 2.4 3 0 0 3 3 3 0 Cobalt uptake substrate-specific transmembrane region FixQ PF05545.11 OAG41092.1 - 0.081 12.9 0.1 0.081 12.9 0.1 2.5 1 1 1 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ DUF981 PF06168.11 OAG41092.1 - 0.87 9.5 6.5 1.6 8.6 1.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF981) LpxC PF03331.13 OAG41093.1 - 0.058 12.9 0.0 0.063 12.8 0.0 1.1 1 0 0 1 1 1 0 UDP-3-O-acyl N-acetylglycosamine deacetylase DnaJ PF00226.31 OAG41094.1 - 1.3e-19 70.0 0.9 2.5e-19 69.1 0.9 1.5 1 0 0 1 1 1 1 DnaJ domain Aminotran_1_2 PF00155.21 OAG41095.1 - 7.4e-62 209.6 0.0 9.1e-62 209.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II 2OG-FeII_Oxy_3 PF13640.6 OAG41096.1 - 1.6e-10 41.7 0.7 8.6e-09 36.2 0.0 3.4 4 0 0 4 4 4 1 2OG-Fe(II) oxygenase superfamily zf-C2H2_jaz PF12171.8 OAG41098.1 - 1.3e-08 34.9 0.7 2.5e-08 34.0 0.7 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OAG41098.1 - 5.7e-08 32.9 0.8 9.8e-08 32.2 0.8 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-DBF PF07535.12 OAG41098.1 - 0.0013 18.7 0.4 0.0027 17.8 0.4 1.4 1 0 0 1 1 1 1 DBF zinc finger Pyrid_ox_like PF16242.5 OAG41100.1 - 5.4e-20 71.5 0.0 8.3e-17 61.1 0.0 2.3 2 0 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase like Putative_PNPOx PF01243.20 OAG41100.1 - 3.8e-07 30.2 0.0 8.8e-06 25.8 0.0 2.2 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase DEAD PF00270.29 OAG41101.1 - 1.4e-46 158.5 0.0 2.7e-46 157.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAG41101.1 - 2.9e-17 63.0 0.0 2.7e-16 59.9 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG41101.1 - 3.2e-06 27.3 0.0 5.2e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 OAG41101.1 - 0.089 12.1 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit ERCC3_RAD25_C PF16203.5 OAG41101.1 - 0.11 11.7 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Aldolase_II PF00596.21 OAG41102.1 - 2.1e-49 168.0 0.0 2.7e-49 167.6 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain SGL PF08450.12 OAG41103.1 - 9.8e-07 28.6 0.0 1.7e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 OAG41103.1 - 0.073 13.3 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 Arylesterase zf-FLZ PF04570.14 OAG41104.1 - 0.12 11.9 4.8 0.3 10.6 0.8 2.4 1 1 1 2 2 2 0 zinc-finger of the FCS-type, C2-C2 BIR PF00653.21 OAG41105.1 - 3.6e-48 162.1 2.9 1e-23 83.7 0.0 2.5 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain zf-BED PF02892.15 OAG41105.1 - 0.072 13.1 0.1 18 5.4 0.0 2.6 2 0 0 2 2 2 0 BED zinc finger zf-C3HC PF07967.13 OAG41105.1 - 0.078 13.0 2.7 9.9 6.2 0.6 3.1 1 1 1 3 3 3 0 C3HC zinc finger-like AP3D1 PF06375.11 OAG41105.1 - 2.1 8.6 7.5 4.5 7.5 7.5 1.6 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 Tam41_Mmp37 PF09139.11 OAG41106.1 - 1.1e-129 432.6 0.0 1.3e-129 432.3 0.0 1.1 1 0 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial MAPEG PF01124.18 OAG41107.1 - 4.1e-13 49.4 2.2 5.3e-13 49.0 2.2 1.2 1 0 0 1 1 1 1 MAPEG family TMEM208_SND2 PF05620.11 OAG41107.1 - 0.023 14.5 0.1 0.045 13.5 0.1 1.5 1 0 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 DUF1664 PF07889.12 OAG41108.1 - 0.011 15.7 0.0 0.089 12.8 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF2353 PF09789.9 OAG41108.1 - 0.025 14.0 0.0 0.036 13.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) Baculo_PEP_C PF04513.12 OAG41108.1 - 0.057 13.5 0.0 0.4 10.7 0.0 2.1 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Tup_N PF08581.10 OAG41108.1 - 0.071 13.4 0.2 0.3 11.4 0.4 2.0 2 0 0 2 2 2 0 Tup N-terminal Type2_restr_D3 PF16902.5 OAG41108.1 - 0.084 12.8 1.1 1.5 8.8 0.1 2.4 1 1 1 2 2 2 0 Type-2 restriction enzyme D3 domain CENP-H PF05837.12 OAG41108.1 - 0.088 13.2 0.0 0.16 12.4 0.0 1.4 1 0 0 1 1 1 0 Centromere protein H (CENP-H) AIP3 PF03915.13 OAG41108.1 - 0.12 11.5 0.2 0.23 10.5 0.1 1.5 1 1 0 1 1 1 0 Actin interacting protein 3 GnsAB_toxin PF08178.11 OAG41108.1 - 0.2 11.6 0.4 21 5.1 0.0 3.0 2 1 2 4 4 4 0 GnsA/GnsB toxin of bacterial toxin-antitoxin system NAD_binding_2 PF03446.15 OAG41110.1 - 6.7e-29 101.1 0.0 1.4e-28 100.0 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 OAG41110.1 - 8.5e-23 80.9 0.8 1.7e-19 70.2 0.0 2.9 3 0 0 3 3 3 2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 OAG41110.1 - 1.2e-06 29.1 0.2 5.1e-06 27.0 0.0 2.2 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 OAG41110.1 - 0.0033 17.3 0.0 0.0078 16.1 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 OAG41110.1 - 0.14 11.7 0.0 0.96 9.0 0.0 2.2 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain CAF-1_p150 PF11600.8 OAG41111.1 - 0.11 12.2 0.1 0.11 12.2 0.1 2.6 3 0 0 3 3 3 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal UBA_e1_thiolCys PF10585.9 OAG41111.1 - 0.13 12.2 5.2 0.25 11.2 5.2 1.4 1 0 0 1 1 1 0 Ubiquitin-activating enzyme active site DUF2722 PF10846.8 OAG41111.1 - 0.52 9.2 0.0 0.52 9.2 0.0 3.2 1 1 1 3 3 3 0 Protein of unknown function (DUF2722) RabGAP-TBC PF00566.18 OAG41112.1 - 1.4e-32 113.1 0.0 2.1e-32 112.5 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF1005 PF06219.12 OAG41112.1 - 0.0051 15.9 0.1 0.0089 15.1 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1005) Sas10_Utp3 PF04000.15 OAG41113.1 - 8.4e-15 55.2 0.5 2.6e-14 53.6 0.5 1.8 1 0 0 1 1 1 1 Sas10/Utp3/C1D family PMSI1 PF15322.6 OAG41113.1 - 0.31 10.4 3.4 0.52 9.7 3.4 1.3 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative Striatin PF08232.12 OAG41113.1 - 3.5 8.2 11.9 1.6 9.3 7.2 2.6 2 1 0 2 2 2 0 Striatin family Tautomerase_3 PF14832.6 OAG41114.1 - 2.2e-45 154.3 0.1 2.5e-45 154.1 0.1 1.0 1 0 0 1 1 1 1 Putative oxalocrotonate tautomerase enzyme Tautomerase PF01361.21 OAG41114.1 - 3.1e-05 23.8 0.0 6.9e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Tautomerase enzyme GlcNAc_2-epim PF07221.11 OAG41114.1 - 0.12 11.5 0.0 0.15 11.3 0.0 1.0 1 0 0 1 1 1 0 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) Peptidase_C13 PF01650.18 OAG41115.1 - 2.7e-40 138.5 0.0 4.2e-40 137.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase C13 family F-box-like PF12937.7 OAG41116.1 - 0.0046 16.8 0.3 0.21 11.5 0.1 2.3 2 0 0 2 2 2 2 F-box-like Fasciclin PF02469.22 OAG41117.1 - 4.7e-26 91.5 0.0 3.1e-16 59.7 0.0 2.2 2 0 0 2 2 2 2 Fasciclin domain DUF347 PF03988.12 OAG41117.1 - 0.0012 19.0 0.1 0.0028 17.8 0.1 1.7 1 0 0 1 1 1 1 Repeat of Unknown Function (DUF347) SKG6 PF08693.10 OAG41117.1 - 0.27 10.7 1.3 0.5 9.8 1.3 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Polysacc_deac_1 PF01522.21 OAG41118.1 - 6.5e-19 68.0 0.1 4.1e-18 65.5 0.0 2.0 1 1 1 2 2 2 1 Polysaccharide deacetylase CDC45 PF02724.14 OAG41119.1 - 4.3e-234 778.6 13.8 3.7e-232 772.2 13.8 3.1 1 1 0 1 1 1 1 CDC45-like protein YL1 PF05764.13 OAG41119.1 - 0.0054 16.9 4.5 0.0054 16.9 4.5 3.2 2 1 1 3 3 3 1 YL1 nuclear protein SDA1 PF05285.12 OAG41119.1 - 0.069 12.6 35.4 0.75 9.2 10.5 2.1 2 0 0 2 2 2 0 SDA1 BUD22 PF09073.10 OAG41119.1 - 0.2 11.0 44.0 0.47 9.7 17.0 2.3 2 0 0 2 2 2 0 BUD22 Tom22 PF04281.13 OAG41119.1 - 0.41 10.4 0.0 0.41 10.4 0.0 3.6 3 0 0 3 3 3 0 Mitochondrial import receptor subunit Tom22 Nop14 PF04147.12 OAG41119.1 - 0.94 7.6 33.8 0.56 8.3 9.7 2.1 2 0 0 2 2 2 0 Nop14-like family FAM60A PF15396.6 OAG41119.1 - 3.9 7.4 17.1 0.095 12.7 4.4 2.4 2 0 0 2 2 2 0 Protein Family FAM60A Apt1 PF10351.9 OAG41119.1 - 6.9 5.4 20.3 3.3 6.5 9.8 2.3 2 0 0 2 2 2 0 Golgi-body localisation protein domain DUF3446 PF11928.8 OAG41119.1 - 8.4 6.8 19.7 0.95 9.8 0.6 3.5 3 0 0 3 3 3 0 Early growth response N-terminal domain Lipase_GDSL_2 PF13472.6 OAG41120.1 - 5.8e-15 56.1 0.3 1.2e-14 55.2 0.3 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 OAG41120.1 - 0.0003 20.8 0.0 0.00052 20.0 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DHH PF01368.20 OAG41121.1 - 5.9e-05 23.2 0.3 0.00011 22.3 0.3 1.5 1 0 0 1 1 1 1 DHH family zf-SNAP50_C PF12251.8 OAG41122.1 - 0.047 13.3 1.7 0.35 10.5 1.0 2.1 1 1 1 2 2 2 0 snRNA-activating protein of 50kDa MW C terminal p450 PF00067.22 OAG41123.1 - 9.5e-64 215.8 0.0 1.1e-63 215.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4148 PF13663.6 OAG41123.1 - 0.037 14.2 0.0 0.078 13.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) Med4 PF10018.9 OAG41125.1 - 2.3e-23 82.9 5.6 4e-23 82.1 5.6 1.4 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 Rogdi_lz PF10259.9 OAG41125.1 - 0.04 13.4 1.5 0.066 12.7 1.5 1.3 1 0 0 1 1 1 0 Rogdi leucine zipper containing protein Herpes_UL17 PF04559.12 OAG41125.1 - 0.45 9.3 3.5 0.6 8.9 3.1 1.5 1 1 0 1 1 1 0 Herpesvirus UL17 protein DUF2203 PF09969.9 OAG41125.1 - 3.8 8.2 6.5 6.1 7.6 0.2 3.1 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2203) Sec23_helical PF04815.15 OAG41126.1 - 0.043 13.6 0.2 0.076 12.8 0.2 1.3 1 0 0 1 1 1 0 Sec23/Sec24 helical domain RabGAP-TBC PF00566.18 OAG41127.1 - 4.6e-38 131.0 0.0 1.3e-37 129.6 0.0 1.8 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF3730 PF12530.8 OAG41127.1 - 0.089 12.3 5.3 0.088 12.4 0.4 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3730) ArAE_2_N PF10337.9 OAG41127.1 - 0.21 10.6 0.9 0.86 8.6 0.9 1.9 1 1 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal TIG_plexin PF17960.1 OAG41127.1 - 0.33 11.0 1.6 2.2 8.4 0.0 2.9 3 0 0 3 3 3 0 TIG domain DUF573 PF04504.14 OAG41127.1 - 0.64 10.7 3.6 0.55 10.9 0.4 2.6 2 1 0 2 2 2 0 Protein of unknown function, DUF573 HrpB2 PF09487.10 OAG41127.1 - 0.85 10.1 3.9 25 5.3 0.3 3.0 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB2) DUF3584 PF12128.8 OAG41127.1 - 0.87 7.0 25.5 2 5.8 25.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Mog1 PF04603.12 OAG41127.1 - 2.3 8.6 5.3 4.8 7.6 3.0 2.4 2 0 0 2 2 2 0 Ran-interacting Mog1 protein Occludin_ELL PF07303.13 OAG41127.1 - 3.4 8.5 11.3 2.6 8.8 2.4 3.0 2 0 0 2 2 2 0 Occludin homology domain DUF1664 PF07889.12 OAG41127.1 - 5.6 7.0 15.6 0.2 11.7 3.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) KCNQC3-Ank-G_bd PF11956.8 OAG41127.1 - 7 7.0 9.3 0.4 11.0 0.6 3.1 3 0 0 3 3 3 0 Ankyrin-G binding motif of KCNQ2-3 AAA_13 PF13166.6 OAG41127.1 - 9.7 4.7 16.9 37 2.8 16.9 1.9 1 1 0 1 1 1 0 AAA domain DNA_topoisoIV PF00521.20 OAG41128.1 - 9e-138 459.7 1.4 6.5e-137 456.9 0.0 2.3 2 0 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 OAG41128.1 - 1.3e-52 177.5 5.7 1.3e-52 177.5 5.7 3.1 4 0 0 4 4 4 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 OAG41128.1 - 3.2e-28 98.4 4.8 8.1e-28 97.1 4.8 1.7 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 OAG41128.1 - 7.1e-15 55.5 0.1 2.1e-14 54.0 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 OAG41128.1 - 4.6e-07 30.0 0.0 2.3e-06 27.7 0.0 2.3 1 0 0 1 1 1 1 Toprim domain NusA_N PF08529.11 OAG41128.1 - 0.09 13.1 0.1 0.09 13.1 0.1 4.4 4 1 1 5 5 5 0 NusA N-terminal domain LIDHydrolase PF10230.9 OAG41128.1 - 0.41 10.2 1.9 0.46 10.0 0.1 1.9 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase PBP1_TM PF14812.6 OAG41129.1 - 7.3 7.0 8.1 0.4 11.1 0.7 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nitr_red_alph_N PF14710.6 OAG41131.1 - 0.25 11.9 1.5 2.7 8.5 0.9 2.6 2 0 0 2 2 2 0 Respiratory nitrate reductase alpha N-terminal Fungal_trans PF04082.18 OAG41132.1 - 2.4e-11 43.2 1.0 4.1e-11 42.4 1.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pkinase PF00069.25 OAG41134.1 - 1.7e-69 234.1 0.0 2.4e-69 233.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG41134.1 - 7.4e-33 113.9 0.0 1.1e-32 113.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 OAG41134.1 - 4.6e-09 36.8 0.1 4.6e-09 36.8 0.1 2.0 2 0 0 2 2 2 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 OAG41134.1 - 5.7e-06 25.5 0.0 8.3e-06 25.0 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 OAG41134.1 - 0.0063 15.9 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like ZZ PF00569.17 OAG41135.1 - 2.2e-09 37.0 5.5 4.2e-09 36.1 5.5 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type SWIRM PF04433.17 OAG41135.1 - 6.3e-09 36.1 0.0 1.7e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.31 OAG41135.1 - 1.1e-08 35.1 1.7 1.5e-08 34.7 0.0 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain zf-UBR PF02207.20 OAG41135.1 - 2.2 8.5 6.6 5.9 7.1 6.6 1.7 1 1 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) Caudo_TAP PF02413.17 OAG41136.1 - 0.012 15.8 0.1 0.012 15.7 0.1 1.2 1 0 0 1 1 1 0 Caudovirales tail fibre assembly protein, lambda gpK GDC-P PF02347.16 OAG41137.1 - 9.1e-180 598.1 0.0 1.7e-166 554.4 0.0 2.8 3 1 0 3 3 3 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.21 OAG41137.1 - 6.7e-08 32.1 0.1 1.5e-07 31.0 0.1 1.5 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 OAG41137.1 - 1.1e-06 27.9 0.6 0.00015 20.9 0.1 2.3 2 0 0 2 2 2 2 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 OAG41137.1 - 0.00037 19.1 0.2 0.022 13.3 0.1 2.2 2 0 0 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme SepSecS PF05889.13 OAG41137.1 - 0.011 14.4 0.1 0.04 12.6 0.0 1.8 2 0 0 2 2 2 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS DegT_DnrJ_EryC1 PF01041.17 OAG41137.1 - 0.085 12.2 0.2 0.32 10.2 0.0 2.0 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Arylsulfotran_2 PF14269.6 OAG41138.1 - 2.8e-53 181.2 3.2 4.8e-53 180.5 3.2 1.3 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 OAG41138.1 - 3.8e-21 75.4 1.7 1.1e-20 74.0 1.7 1.7 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) S-l_SbsC_C PF18316.1 OAG41138.1 - 0.06 13.8 0.0 0.2 12.1 0.0 1.9 2 0 0 2 2 2 0 S-layer protein SbsC C-terminal domain F-box PF00646.33 OAG41139.1 - 0.00071 19.4 0.0 0.0019 18.0 0.0 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 OAG41139.1 - 0.0042 17.0 0.4 0.019 14.8 0.1 2.2 2 0 0 2 2 2 1 F-box-like MgtE_N PF03448.17 OAG41139.1 - 0.18 12.4 0.0 0.35 11.5 0.0 1.4 1 0 0 1 1 1 0 MgtE intracellular N domain UFD1 PF03152.14 OAG41140.1 - 5.1e-27 94.4 0.0 4e-23 81.8 0.0 3.4 3 1 0 3 3 3 2 Ubiquitin fusion degradation protein UFD1 AZUL PF16558.5 OAG41140.1 - 0.0014 18.8 0.0 0.0048 17.1 0.0 1.9 1 0 0 1 1 1 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A HOIP-UBA PF16678.5 OAG41140.1 - 0.016 15.3 0.0 0.034 14.1 0.0 1.5 1 0 0 1 1 1 0 HOIP UBA domain pair MCR PF18509.1 OAG41140.1 - 0.025 14.2 1.7 0.26 10.9 0.1 3.0 2 0 0 2 2 2 0 Magnetochrome domain UBA PF00627.31 OAG41140.1 - 0.11 12.4 0.3 0.37 10.8 0.3 2.0 1 0 0 1 1 1 0 UBA/TS-N domain DUF1360 PF07098.11 OAG41141.1 - 0.14 12.1 1.4 0.86 9.6 0.0 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF1360) Ring_hydroxyl_A PF00848.19 OAG41142.1 - 1e-15 58.3 4.4 2e-13 50.8 0.0 2.3 2 0 0 2 2 2 2 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.26 OAG41142.1 - 8e-15 54.6 0.0 1.4e-14 53.7 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Fungal_trans_2 PF11951.8 OAG41143.1 - 7.5e-39 133.6 0.2 2.4e-38 131.9 0.2 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG41143.1 - 0.00034 20.7 10.1 0.00057 19.9 10.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PhyH PF05721.13 OAG41144.1 - 4e-26 92.6 0.0 5.2e-26 92.2 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) AA_permease_2 PF13520.6 OAG41145.1 - 2.2e-36 125.6 46.2 2.7e-36 125.3 46.2 1.1 1 0 0 1 1 1 1 Amino acid permease DUF3341 PF11821.8 OAG41145.1 - 1.4 8.6 6.4 0.39 10.4 1.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3341) ABC1 PF03109.16 OAG41147.1 - 6.8e-21 74.6 0.0 2.6e-11 43.7 0.0 2.8 3 0 0 3 3 3 2 ABC1 family Raf1_HTH PF18579.1 OAG41147.1 - 0.032 13.9 0.0 0.065 12.9 0.0 1.5 1 0 0 1 1 1 0 Rubisco accumulation factor 1 helix turn helix domain MFS_1 PF07690.16 OAG41148.1 - 4.4e-36 124.5 31.1 6e-36 124.1 31.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily LapA_dom PF06305.11 OAG41148.1 - 0.02 14.7 1.8 3 7.7 0.1 3.9 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain DUF3925 PF13063.6 OAG41148.1 - 0.052 13.8 3.2 0.23 11.7 3.2 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3925) Menin PF05053.13 OAG41149.1 - 3.2 6.0 3.8 6.6 5.0 3.8 1.4 1 0 0 1 1 1 0 Menin BTB PF00651.31 OAG41150.1 - 0.023 14.9 0.0 0.055 13.7 0.0 1.6 1 0 0 1 1 1 0 BTB/POZ domain MFS_1 PF07690.16 OAG41153.1 - 8.1e-30 103.9 36.6 2.1e-26 92.7 22.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG41153.1 - 2.7e-09 36.4 6.0 2.7e-09 36.4 6.0 3.0 3 0 0 3 3 3 2 Sugar (and other) transporter MFS_3 PF05977.13 OAG41153.1 - 0.0065 14.9 3.3 0.012 14.0 3.3 1.4 1 0 0 1 1 1 1 Transmembrane secretion effector His_Phos_2 PF00328.22 OAG41154.1 - 9.2e-38 130.6 0.0 2.4e-37 129.2 0.0 1.6 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Voltage_CLC PF00654.20 OAG41155.1 - 0.26 10.5 3.6 0.27 10.4 2.0 1.6 1 1 1 2 2 2 0 Voltage gated chloride channel Tetraspanin PF00335.20 OAG41155.1 - 3.6 7.2 7.1 14 5.3 7.1 1.8 1 1 0 1 1 1 0 Tetraspanin family FAD_binding_3 PF01494.19 OAG41156.1 - 8.4e-11 41.7 3.4 1.6e-05 24.4 0.2 3.3 3 0 0 3 3 3 3 FAD binding domain DAO PF01266.24 OAG41156.1 - 2.3e-06 27.4 0.5 3.5e-06 26.8 0.5 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAG41156.1 - 0.0051 17.0 0.1 0.031 14.5 0.1 2.4 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAG41156.1 - 0.0091 15.3 0.1 2.6 7.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Neisseria_TspB PF05616.13 OAG41156.1 - 0.018 13.5 1.5 0.031 12.7 1.5 1.3 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein IQ PF00612.27 OAG41157.1 - 2e-05 24.0 1.2 6.2e-05 22.4 1.2 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif APG6_N PF17675.1 OAG41157.1 - 1.9 9.0 15.9 0.035 14.6 2.7 2.8 3 0 0 3 3 3 0 Apg6 coiled-coil region Fungal_trans PF04082.18 OAG41158.1 - 8.9e-29 100.3 0.0 1.5e-28 99.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG41158.1 - 2.2e-05 24.5 12.3 5.7e-05 23.2 12.3 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UTP15_C PF09384.10 OAG41158.1 - 0.062 13.0 0.1 0.21 11.3 0.1 1.8 1 1 0 1 1 1 0 UTP15 C terminal Peptidase_S10 PF00450.22 OAG41159.1 - 2.1e-99 333.8 1.5 2.4e-99 333.6 1.5 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase DUF3659 PF12396.8 OAG41160.1 - 4.3e-271 875.3 162.4 6.7e-24 83.6 0.5 14.2 14 0 0 14 14 14 13 Protein of unknown function (DUF3659) Alanine_zipper PF11839.8 OAG41160.1 - 0.0009 19.6 20.0 0.0009 19.6 20.0 6.6 6 2 0 6 6 6 1 Alanine-zipper, major outer membrane lipoprotein DUF4172 PF13776.6 OAG41160.1 - 0.02 15.2 1.0 1.1e+02 3.2 0.0 6.3 6 0 0 6 6 6 0 Domain of unknown function (DUF4172) RPW8 PF05659.11 OAG41160.1 - 0.89 9.2 7.3 0.047 13.4 1.2 2.0 3 0 0 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Phage_fiber_C PF06820.12 OAG41160.1 - 1.7 9.0 12.3 1.1e+02 3.2 0.0 7.5 8 0 0 8 8 8 0 Putative prophage tail fibre C-terminus Syntaxin_2 PF14523.6 OAG41160.1 - 6.8 7.1 5.4 16 6.0 0.5 3.5 4 0 0 4 4 4 0 Syntaxin-like protein Acetyltransf_10 PF13673.7 OAG41161.1 - 0.0026 17.7 0.0 0.0046 16.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OAG41161.1 - 0.0027 18.1 0.0 0.0047 17.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAG41161.1 - 0.0089 16.3 0.0 0.02 15.1 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family NMO PF03060.15 OAG41162.1 - 8.5e-57 193.0 4.3 1.3e-56 192.4 4.3 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 OAG41162.1 - 3.2e-10 39.5 5.7 4.5e-10 39.1 5.7 1.2 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 OAG41162.1 - 2.7e-07 29.9 3.6 4.9e-07 29.1 3.6 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase PEP_hydrolase PF09370.10 OAG41162.1 - 0.035 13.3 0.1 0.073 12.3 0.1 1.5 1 0 0 1 1 1 0 Phosphoenolpyruvate hydrolase-like DUF1729 PF08354.10 OAG41162.1 - 0.045 12.6 0.8 0.16 10.8 0.8 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF1729) TGT PF01702.18 OAG41162.1 - 0.046 12.9 0.0 0.072 12.2 0.0 1.3 1 0 0 1 1 1 0 Queuine tRNA-ribosyltransferase Glu_synthase PF01645.17 OAG41162.1 - 0.07 12.2 4.3 0.029 13.5 1.9 1.5 2 0 0 2 2 2 0 Conserved region in glutamate synthase DHO_dh PF01180.21 OAG41162.1 - 0.074 12.2 0.7 0.15 11.2 0.7 1.5 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase NmrA PF05368.13 OAG41164.1 - 2.6e-05 23.9 0.0 3.9e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family AAA PF00004.29 OAG41165.1 - 1.3e-48 164.8 0.2 6.3e-41 139.9 0.0 3.7 4 0 0 4 4 3 3 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OAG41165.1 - 1.5e-16 59.9 1.5 1.3e-09 37.7 0.4 2.7 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 OAG41165.1 - 2e-10 41.3 0.4 0.0035 17.7 0.0 3.7 2 2 0 3 3 3 2 AAA ATPase domain AAA_5 PF07728.14 OAG41165.1 - 2.5e-07 30.8 0.3 0.0015 18.5 0.1 3.1 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) DUF815 PF05673.13 OAG41165.1 - 1.7e-06 27.4 0.0 0.0029 16.8 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) Rad17 PF03215.15 OAG41165.1 - 6.1e-06 26.3 0.0 0.0041 17.1 0.0 2.4 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_28 PF13521.6 OAG41165.1 - 3.7e-05 24.0 0.1 0.28 11.4 0.1 2.6 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.12 OAG41165.1 - 5.4e-05 23.0 0.0 0.0033 17.2 0.0 2.8 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 OAG41165.1 - 0.00017 21.9 0.1 1.9 8.8 0.0 3.3 2 1 1 3 3 3 2 AAA domain RNA_helicase PF00910.22 OAG41165.1 - 0.00047 20.5 0.0 1.2 9.6 0.0 2.5 2 0 0 2 2 2 2 RNA helicase TIP49 PF06068.13 OAG41165.1 - 0.00061 19.1 0.1 0.04 13.1 0.0 2.2 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_25 PF13481.6 OAG41165.1 - 0.00062 19.4 1.3 0.26 10.9 0.1 2.7 2 1 1 3 3 3 1 AAA domain AAA_7 PF12775.7 OAG41165.1 - 0.0014 18.2 0.0 0.99 8.9 0.0 2.6 3 0 0 3 3 3 1 P-loop containing dynein motor region IstB_IS21 PF01695.17 OAG41165.1 - 0.0015 18.3 0.0 1.1 8.9 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_2 PF07724.14 OAG41165.1 - 0.0016 18.6 0.0 0.0044 17.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) ATPase_2 PF01637.18 OAG41165.1 - 0.0023 17.9 0.0 6.3 6.6 0.0 3.2 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea AAA_29 PF13555.6 OAG41165.1 - 0.0029 17.3 0.0 0.083 12.7 0.0 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain Adeno_IVa2 PF02456.15 OAG41165.1 - 0.0035 16.2 0.0 1.4 7.6 0.0 2.3 2 0 0 2 2 2 2 Adenovirus IVa2 protein Bac_DnaA PF00308.18 OAG41165.1 - 0.0038 17.1 0.0 2.7 7.8 0.0 2.6 2 0 0 2 2 2 1 Bacterial dnaA protein TsaE PF02367.17 OAG41165.1 - 0.0042 17.1 0.0 0.91 9.5 0.0 2.3 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_3 PF07726.11 OAG41165.1 - 0.0084 16.0 0.0 0.18 11.6 0.0 3.0 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 OAG41165.1 - 0.012 15.0 0.1 1.4 8.3 0.0 2.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ABC_tran PF00005.27 OAG41165.1 - 0.013 16.0 0.0 12 6.5 0.0 2.7 2 0 0 2 2 2 0 ABC transporter AAA_33 PF13671.6 OAG41165.1 - 0.016 15.4 0.0 1.2 9.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain CDC48_N PF02359.18 OAG41165.1 - 0.016 15.3 0.0 0.11 12.7 0.0 2.4 2 0 0 2 2 2 0 Cell division protein 48 (CDC48), N-terminal domain NACHT PF05729.12 OAG41165.1 - 0.027 14.4 0.1 9.4 6.1 0.1 2.5 2 0 0 2 2 2 0 NACHT domain Sigma54_activ_2 PF14532.6 OAG41165.1 - 0.039 14.1 0.0 0.4 10.8 0.0 2.4 3 0 0 3 3 2 0 Sigma-54 interaction domain AAA_14 PF13173.6 OAG41165.1 - 0.055 13.5 0.0 1.6 8.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain AFG1_ATPase PF03969.16 OAG41165.1 - 0.13 11.1 0.0 5.5 5.8 0.0 2.2 2 0 0 2 2 2 0 AFG1-like ATPase zinc_ribbon_10 PF10058.9 OAG41166.1 - 7e-13 48.1 0.0 1.2e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein Adeno_E3B PF03376.14 OAG41166.1 - 0.26 11.6 1.9 0.94 9.8 1.9 1.9 1 1 0 1 1 1 0 Adenovirus E3B protein ADH_zinc_N PF00107.26 OAG41167.1 - 5.5e-15 55.5 0.0 9.3e-15 54.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG41167.1 - 0.00038 20.3 0.5 0.0014 18.4 0.1 2.1 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 OAG41167.1 - 0.0024 18.9 0.0 0.0045 18.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Zip PF02535.22 OAG41168.1 - 3.7e-42 144.7 12.1 3.7e-42 144.7 12.1 2.1 2 0 0 2 2 2 2 ZIP Zinc transporter HRXXH PF13933.6 OAG41169.1 - 4e-106 354.1 0.1 4.8e-106 353.8 0.1 1.1 1 0 0 1 1 1 1 Putative peptidase family Aspzincin_M35 PF14521.6 OAG41169.1 - 0.00021 21.9 0.0 0.00036 21.1 0.0 1.4 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase Pyridoxal_deC PF00282.19 OAG41170.1 - 8e-110 367.1 0.0 1e-109 366.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain ZapB PF06005.12 OAG41170.1 - 0.26 11.8 2.1 1.2 9.7 0.2 2.2 2 0 0 2 2 2 0 Cell division protein ZapB SMC_Nse1 PF07574.13 OAG41171.1 - 2.2e-60 203.9 0.1 3.9e-60 203.1 0.1 1.4 1 0 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex Glyco_hydro_65N PF03636.15 OAG41171.1 - 1e-33 116.9 0.1 1.6e-33 116.2 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_65m PF03632.15 OAG41171.1 - 1.1e-25 90.3 2.1 6.3e-20 71.4 0.5 2.4 1 1 1 2 2 2 2 Glycosyl hydrolase family 65 central catalytic domain PaaX PF07848.12 OAG41171.1 - 0.042 14.1 0.0 0.12 12.6 0.0 1.8 1 0 0 1 1 1 0 PaaX-like protein Glyco_hydro_65C PF03633.15 OAG41171.1 - 0.047 13.6 0.1 0.12 12.3 0.1 1.7 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, C-terminal domain CBFD_NFYB_HMF PF00808.23 OAG41172.1 - 2.6e-11 43.6 0.2 1.7e-08 34.6 0.0 2.2 2 0 0 2 2 2 2 Histone-like transcription factor (CBF/NF-Y) and archaeal histone adh_short PF00106.25 OAG41173.1 - 1.3e-37 129.2 0.0 1.6e-37 128.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG41173.1 - 2.7e-23 82.8 0.0 3.2e-23 82.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG41173.1 - 8.1e-14 51.9 0.1 6.1e-12 45.8 0.0 2.0 1 1 1 2 2 2 2 KR domain DUF1776 PF08643.10 OAG41173.1 - 0.0049 16.3 0.0 0.0063 15.9 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Polysacc_synt_2 PF02719.15 OAG41173.1 - 0.009 15.2 0.0 0.057 12.6 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 OAG41173.1 - 0.013 15.0 0.1 0.27 10.6 0.1 2.2 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family FAA_hydrolase PF01557.18 OAG41174.1 - 1.3e-59 201.5 0.0 1.9e-59 201.0 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Fasciclin PF02469.22 OAG41175.1 - 2.1e-21 76.5 0.0 2.9e-09 37.2 0.0 2.2 2 0 0 2 2 2 2 Fasciclin domain SKG6 PF08693.10 OAG41175.1 - 0.00099 18.5 3.9 0.0019 17.5 3.9 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain CcmD PF04995.14 OAG41175.1 - 0.12 12.5 3.8 0.25 11.5 3.8 1.5 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) adh_short_C2 PF13561.6 OAG41176.1 - 2e-59 201.0 4.2 7.4e-59 199.1 4.2 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG41176.1 - 7.1e-48 162.7 1.8 2.2e-47 161.1 1.8 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG41176.1 - 2.8e-13 50.2 2.4 6e-13 49.1 2.4 1.6 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OAG41176.1 - 2.4e-06 26.9 0.1 4.3e-06 26.1 0.1 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein E1-E2_ATPase PF00122.20 OAG41177.1 - 1.7e-45 154.8 4.1 1.7e-45 154.8 4.1 2.6 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 OAG41177.1 - 5.6e-17 62.7 0.0 2e-16 60.9 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 OAG41177.1 - 9.2e-08 31.7 0.0 2e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 OAG41177.1 - 0.001 19.1 0.0 0.0021 18.1 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 OAG41177.1 - 0.0032 17.2 0.3 0.0072 16.1 0.1 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase O-antigen_lig PF13425.6 OAG41177.1 - 0.13 11.1 5.1 0.29 9.9 5.1 1.5 1 0 0 1 1 1 0 O-antigen ligase like membrane protein CTD_bind PF04818.13 OAG41178.1 - 6.7e-09 36.4 0.0 1.3e-08 35.5 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase II-binding domain. RRM_1 PF00076.22 OAG41178.1 - 1.6e-07 31.1 0.0 2.7e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TFIIA PF03153.13 OAG41178.1 - 5.4 6.9 6.2 7.9 6.4 6.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Citrate_synt PF00285.21 OAG41179.1 - 1.2e-100 337.1 0.0 1.5e-100 336.8 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Eclosion PF04736.12 OAG41179.1 - 0.089 12.5 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Eclosion hormone Mito_carr PF00153.27 OAG41180.1 - 2e-27 94.9 4.7 4.6e-11 42.5 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein PALP PF00291.25 OAG41181.1 - 1.9e-69 234.3 0.2 2.4e-69 234.0 0.2 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Amidohydro_1 PF01979.20 OAG41182.1 - 1.7e-26 93.4 0.0 7.5e-26 91.2 0.0 1.9 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 OAG41182.1 - 2.7e-20 73.3 0.8 5.5e-10 39.3 0.0 3.2 2 1 0 3 3 3 3 Amidohydrolase family Urease_alpha PF00449.20 OAG41182.1 - 0.036 14.4 1.0 0.061 13.7 0.2 1.8 2 0 0 2 2 2 0 Urease alpha-subunit, N-terminal domain NTP_transf_2 PF01909.23 OAG41182.1 - 0.098 13.0 0.0 0.18 12.1 0.0 1.3 1 0 0 1 1 1 0 Nucleotidyltransferase domain tRNA-synt_1c PF00749.21 OAG41183.1 - 5.4e-102 340.9 0.1 7e-102 340.5 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 OAG41183.1 - 6.1e-32 110.9 1.1 1.8e-31 109.3 1.1 1.8 1 1 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA-synt_1e PF01406.19 OAG41183.1 - 0.036 13.4 0.4 0.075 12.4 0.4 1.5 1 1 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain Ribosomal_L1 PF00687.21 OAG41184.1 - 1.9e-27 96.3 0.1 4.1e-27 95.3 0.0 1.3 1 1 0 1 1 1 1 Ribosomal protein L1p/L10e family COG2 PF06148.11 OAG41185.1 - 5.5e-32 110.6 1.2 5.5e-32 110.6 1.2 2.0 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.11 OAG41185.1 - 1.5e-06 28.2 2.4 3.9e-06 26.8 0.4 2.4 1 1 1 2 2 2 1 Vps51/Vps67 COG5 PF10392.9 OAG41185.1 - 0.00054 20.2 0.7 0.00054 20.2 0.7 2.1 2 0 0 2 2 2 1 Golgi transport complex subunit 5 DUF16 PF01519.16 OAG41185.1 - 0.0015 19.0 3.3 0.0066 16.9 0.3 2.3 2 1 0 2 2 2 1 Protein of unknown function DUF16 kleA_kleC PF17383.2 OAG41185.1 - 0.0091 16.3 0.9 0.023 15.0 0.9 1.6 1 0 0 1 1 1 1 Uncharacterized KorC regulated protein A TSC22 PF01166.18 OAG41185.1 - 0.0099 16.2 0.6 0.0099 16.2 0.6 2.6 3 0 0 3 3 3 1 TSC-22/dip/bun family NPV_P10 PF05531.12 OAG41185.1 - 0.1 13.1 7.4 0.51 10.8 0.2 3.3 4 2 0 4 4 4 0 Nucleopolyhedrovirus P10 protein YkuI_C PF10388.9 OAG41185.1 - 0.13 12.0 0.2 1.5 8.6 0.0 2.3 2 1 0 3 3 3 0 EAL-domain associated signalling protein domain SGS PF05002.15 OAG41186.1 - 4.5e-23 81.2 12.2 1.5e-22 79.4 10.0 2.7 2 1 0 2 2 2 1 SGS domain CS PF04969.16 OAG41186.1 - 3.1e-15 56.9 0.1 6.5e-15 55.9 0.1 1.6 1 0 0 1 1 1 1 CS domain TPR_16 PF13432.6 OAG41186.1 - 0.017 15.8 4.7 0.15 12.7 0.7 2.9 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 OAG41186.1 - 1.2 9.4 4.9 33 4.9 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat RdRP PF05183.12 OAG41188.1 - 1e-115 387.7 0.0 1.3e-115 387.3 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase Metallophos PF00149.28 OAG41189.1 - 6.8e-36 124.7 0.3 1.3e-35 123.8 0.2 1.6 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase DUF1647 PF07801.11 OAG41189.1 - 0.057 13.2 0.8 2 8.2 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1647) Urate_ox_N PF06181.11 OAG41191.1 - 0.19 11.0 0.0 0.25 10.6 0.0 1.1 1 0 0 1 1 1 0 Urate oxidase N-terminal E1-E2_ATPase PF00122.20 OAG41192.1 - 7.8e-37 126.5 14.0 4.2e-30 104.6 0.3 3.4 3 0 0 3 3 3 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 OAG41192.1 - 5.3e-23 81.7 10.1 5.3e-23 81.7 10.1 2.5 2 1 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 OAG41192.1 - 2.5e-20 73.7 0.0 2.1e-16 60.9 0.0 2.6 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 OAG41192.1 - 3.8e-20 71.8 0.0 7e-20 70.9 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 OAG41192.1 - 6.3e-17 61.0 0.0 1.8e-16 59.6 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 OAG41192.1 - 0.00015 21.6 0.4 0.0044 16.8 0.7 2.5 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Fungal_trans PF04082.18 OAG41193.1 - 9.5e-09 34.7 0.0 1.4e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short_C2 PF13561.6 OAG41193.1 - 1.2e-08 34.8 4.8 1.6e-07 31.1 0.2 2.6 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG41193.1 - 6.3e-05 22.5 0.1 0.027 13.9 0.1 2.5 2 0 0 2 2 2 2 short chain dehydrogenase TolA PF06519.11 OAG41193.1 - 0.0092 16.2 0.0 0.025 14.7 0.0 1.6 1 0 0 1 1 1 1 TolA C-terminal Fungal_trans PF04082.18 OAG41194.1 - 8.6e-23 80.7 2.0 1.5e-22 79.9 2.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain AMP-binding PF00501.28 OAG41195.1 - 4.3e-80 269.4 0.1 5.6e-80 269.0 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG41195.1 - 2.3e-10 41.3 1.4 6.8e-10 39.8 1.4 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ADH_zinc_N PF00107.26 OAG41196.1 - 3.5e-23 82.0 0.5 6e-23 81.2 0.5 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAG41196.1 - 1.8e-12 48.4 0.2 1.1e-11 45.9 0.1 2.2 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG41196.1 - 1.7e-05 24.6 0.0 5.7e-05 23.0 0.0 1.9 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 OAG41196.1 - 0.011 15.2 0.1 0.015 14.8 0.1 1.2 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus MFS_1 PF07690.16 OAG41197.1 - 2.2e-24 86.1 32.1 2.2e-24 86.1 32.1 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily ECH_1 PF00378.20 OAG41198.1 - 2e-51 174.8 0.0 3e-51 174.2 0.0 1.2 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAG41198.1 - 1.5e-30 106.9 0.1 4.7e-26 92.1 0.0 2.1 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 OAG41198.1 - 0.0021 18.0 0.0 0.025 14.5 0.0 2.3 3 0 0 3 3 3 1 Peptidase family S49 DUF3005 PF11448.8 OAG41198.1 - 0.025 14.6 0.0 0.75 9.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3005) SDH_sah PF01972.16 OAG41198.1 - 0.066 12.2 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Serine dehydrogenase proteinase MFS_1 PF07690.16 OAG41199.1 - 2e-38 132.3 19.2 2.7e-38 131.8 19.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Stevor PF17410.2 OAG41200.1 - 0.06 12.9 0.3 0.087 12.3 0.3 1.3 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame DUF3180 PF11377.8 OAG41200.1 - 0.12 12.5 8.9 2.4 8.3 5.4 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3180) DUF1218 PF06749.12 OAG41200.1 - 0.18 12.3 2.4 1.7 9.2 0.1 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF1218) Bax1-I PF01027.20 OAG41200.1 - 0.98 9.2 10.1 0.19 11.5 3.1 2.2 2 0 0 2 2 2 0 Inhibitor of apoptosis-promoting Bax1 DUF4267 PF14087.6 OAG41200.1 - 1.7 8.7 10.4 30 4.7 0.3 3.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4267) MnhB PF04039.13 OAG41200.1 - 1.8 8.9 11.9 0.24 11.7 0.9 2.8 2 2 2 4 4 4 0 Domain related to MnhB subunit of Na+/H+ antiporter Peptidase_S28 PF05577.12 OAG41201.1 - 6.4e-41 140.6 0.0 2.1e-36 125.7 0.0 2.1 2 0 0 2 2 2 2 Serine carboxypeptidase S28 Peptidase_S9 PF00326.21 OAG41201.1 - 2.7e-09 36.8 0.0 3.6e-07 29.9 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 OAG41201.1 - 0.00026 20.4 0.0 0.025 13.8 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 DUF2920 PF11144.8 OAG41201.1 - 0.0046 16.2 0.0 0.0076 15.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2920) Abhydrolase_1 PF00561.20 OAG41201.1 - 0.035 13.7 0.0 0.064 12.9 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG41201.1 - 0.037 14.6 0.0 0.97 10.0 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase family 2OG-FeII_Oxy PF03171.20 OAG41203.1 - 4.2e-17 62.5 0.0 7.8e-17 61.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 OAG41203.1 - 3.1e-08 34.4 0.0 1.1e-07 32.6 0.0 1.8 1 1 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal GAT PF03127.14 OAG41203.1 - 0.21 11.9 0.0 0.38 11.1 0.0 1.3 1 0 0 1 1 1 0 GAT domain His_Phos_1 PF00300.22 OAG41204.1 - 2.2e-05 24.3 0.0 5.6e-05 22.9 0.0 1.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DAO PF01266.24 OAG41205.1 - 2.1e-45 155.8 1.5 3.2e-45 155.3 1.5 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 OAG41205.1 - 0.0003 21.3 0.0 0.77 10.4 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAG41205.1 - 0.0019 17.5 0.0 0.91 8.7 0.1 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG41205.1 - 0.015 15.5 0.4 0.038 14.2 0.4 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain MCRA PF06100.11 OAG41205.1 - 0.27 10.0 0.3 0.44 9.3 0.3 1.3 1 0 0 1 1 1 0 MCRA family DUF3245 PF11595.8 OAG41206.1 - 8.9e-07 29.5 3.4 8.9e-07 29.5 3.4 2.0 2 1 0 2 2 2 1 Protein of unknown function (DUF3245) HSF_DNA-bind PF00447.17 OAG41207.1 - 2.9e-30 104.8 2.1 4.5e-30 104.1 2.1 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding Peptidase_C97 PF05903.14 OAG41207.1 - 0.08 12.8 0.1 7.9 6.3 0.0 2.2 1 1 1 2 2 2 0 PPPDE putative peptidase domain Sugarporin_N PF11471.8 OAG41207.1 - 0.11 12.5 0.2 0.21 11.5 0.2 1.4 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension Ets PF00178.22 OAG41207.1 - 0.17 12.4 0.1 0.32 11.5 0.1 1.4 1 0 0 1 1 1 0 Ets-domain EzrA PF06160.12 OAG41207.1 - 0.18 9.9 0.1 0.25 9.5 0.1 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Pkinase PF00069.25 OAG41208.1 - 0.0005 19.5 0.1 0.00081 18.8 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Bystin PF05291.11 OAG41209.1 - 2.3e-127 424.3 0.0 2.9e-127 424.0 0.0 1.1 1 0 0 1 1 1 1 Bystin Amidase PF01425.21 OAG41210.1 - 1.7e-109 366.8 0.3 2e-66 224.8 2.8 2.0 1 1 0 2 2 2 2 Amidase Fzo_mitofusin PF04799.13 OAG41211.1 - 0.049 13.2 0.2 0.12 11.9 0.2 1.5 1 0 0 1 1 1 0 fzo-like conserved region Zn_clus PF00172.18 OAG41211.1 - 0.22 11.7 2.3 0.54 10.4 2.3 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain HAD_2 PF13419.6 OAG41212.1 - 6.4e-10 39.4 0.0 1.3e-09 38.4 0.0 1.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OAG41212.1 - 1.8e-05 25.2 0.0 4.1e-05 24.0 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase ATP-grasp_2 PF08442.10 OAG41213.1 - 4.1e-79 264.9 0.4 6.8e-79 264.1 0.4 1.4 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 OAG41213.1 - 1.1e-22 80.6 0.3 2.2e-22 79.6 0.3 1.6 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 OAG41213.1 - 8.6e-09 35.2 0.4 2.5e-08 33.7 0.2 1.8 2 0 0 2 2 2 1 ATP-grasp domain VID27_N PF17748.1 OAG41213.1 - 0.047 13.5 0.6 0.084 12.7 0.6 1.3 1 0 0 1 1 1 0 VID27 N-terminal region GARS_A PF01071.19 OAG41213.1 - 0.056 13.2 0.3 0.14 11.9 0.1 1.8 2 1 0 2 2 2 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain DAO_C PF16901.5 OAG41213.1 - 0.15 12.0 0.0 1.7 8.5 0.0 2.4 3 0 0 3 3 3 0 C-terminal domain of alpha-glycerophosphate oxidase SLAC1 PF03595.17 OAG41214.1 - 9.2e-78 261.7 52.9 1.1e-77 261.5 52.9 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel DUF5453 PF17534.2 OAG41214.1 - 5 7.0 8.0 1.5 8.7 0.8 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF5453) Pro_CA PF00484.19 OAG41215.1 - 6.9e-15 55.7 0.0 1.2e-14 54.9 0.0 1.4 1 1 0 1 1 1 1 Carbonic anhydrase GCIP PF13324.6 OAG41216.1 - 5e-24 85.3 0.5 7e-24 84.8 0.5 1.2 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting Sigma70_ner PF04546.13 OAG41216.1 - 0.003 17.5 0.6 0.0047 16.8 0.6 1.4 1 0 0 1 1 1 1 Sigma-70, non-essential region PMC2NT PF08066.12 OAG41216.1 - 0.23 12.1 2.1 18 6.1 0.0 3.0 2 1 1 3 3 3 0 PMC2NT (NUC016) domain ADP_ribosyl_GH PF03747.14 OAG41217.1 - 2.2e-65 221.3 0.2 2.7e-65 221.0 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase TCTP PF00838.17 OAG41217.1 - 0.21 11.9 0.0 0.42 10.9 0.0 1.4 1 0 0 1 1 1 0 Translationally controlled tumour protein Abhydrolase_1 PF00561.20 OAG41218.1 - 7.6e-21 74.9 0.1 3e-18 66.4 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG41218.1 - 3.5e-19 70.3 7.4 6.4e-19 69.4 7.4 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG41218.1 - 7.9e-14 51.5 0.0 1.2e-13 50.9 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 ESCRT-II PF05871.12 OAG41218.1 - 0.14 12.4 0.1 0.24 11.6 0.1 1.4 1 0 0 1 1 1 0 ESCRT-II complex subunit FAD_binding_4 PF01565.23 OAG41219.1 - 7.6e-23 80.8 3.2 1.4e-22 79.9 3.2 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 OAG41219.1 - 3.5e-13 49.4 0.0 7.3e-13 48.4 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like TPR_12 PF13424.6 OAG41220.1 - 1.7e-65 217.3 7.7 7.3e-15 55.0 0.0 6.8 3 1 3 7 7 7 6 Tetratricopeptide repeat TPR_10 PF13374.6 OAG41220.1 - 1.1e-63 209.5 2.8 5.6e-09 35.6 0.0 8.7 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_1 PF00515.28 OAG41220.1 - 3.8e-26 89.8 10.0 0.017 15.0 0.0 8.7 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_MalT PF17874.1 OAG41220.1 - 1.3e-19 70.7 1.1 1.5e-10 40.9 0.0 3.3 1 1 2 3 3 3 3 MalT-like TPR region TPR_2 PF07719.17 OAG41220.1 - 4.2e-13 48.3 11.3 0.071 13.3 0.0 8.5 8 0 0 8 8 8 3 Tetratricopeptide repeat NB-ARC PF00931.22 OAG41220.1 - 9.2e-13 48.0 0.0 1.6e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain PNP_UDP_1 PF01048.20 OAG41220.1 - 9.9e-12 44.6 2.9 3.9e-11 42.7 2.8 2.1 2 1 0 2 2 2 1 Phosphorylase superfamily TPR_7 PF13176.6 OAG41220.1 - 3.5e-11 42.3 2.1 0.51 10.5 0.0 7.8 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_14 PF13428.6 OAG41220.1 - 7.1e-10 38.9 6.2 9.7 7.3 0.0 9.2 8 1 1 9 9 9 0 Tetratricopeptide repeat TPR_8 PF13181.6 OAG41220.1 - 3.4e-09 36.2 8.7 1.3 9.4 0.0 7.8 8 0 0 8 8 7 2 Tetratricopeptide repeat AAA_16 PF13191.6 OAG41220.1 - 7.2e-05 23.2 0.1 0.00039 20.8 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain TPR_19 PF14559.6 OAG41220.1 - 0.0032 17.9 7.6 0.44 11.1 0.0 5.6 2 2 4 7 7 7 2 Tetratricopeptide repeat PPR PF01535.20 OAG41220.1 - 0.0072 16.5 1.1 76 3.9 0.0 5.8 7 0 0 7 7 7 0 PPR repeat TPR_4 PF07721.14 OAG41220.1 - 0.0073 16.8 0.0 26 5.8 0.0 5.4 7 0 0 7 7 4 0 Tetratricopeptide repeat DUF2225 PF09986.9 OAG41220.1 - 0.022 14.5 0.1 0.15 11.8 0.0 2.3 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_21 PF09976.9 OAG41220.1 - 0.098 12.4 2.0 11 5.6 0.1 4.6 5 1 1 6 6 6 0 Tetratricopeptide repeat-like domain ATPase_2 PF01637.18 OAG41220.1 - 0.2 11.5 0.0 0.37 10.7 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea TPR_16 PF13432.6 OAG41220.1 - 0.38 11.4 15.5 3.1 8.5 0.2 6.8 4 3 1 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 OAG41220.1 - 1.8 9.1 13.1 24 5.6 0.0 6.8 8 0 0 8 8 7 0 Tetratricopeptide repeat AIG1 PF04548.16 OAG41223.1 - 8.4e-12 44.9 0.0 1.7e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.23 OAG41223.1 - 9.9e-10 38.5 0.0 2.3e-09 37.3 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OAG41223.1 - 9.6e-06 25.6 0.1 4e-05 23.6 0.0 2.0 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 OAG41223.1 - 1.5e-05 25.1 2.6 0.43 10.6 0.0 3.2 2 1 1 3 3 3 2 Dynamin family TsaE PF02367.17 OAG41223.1 - 0.0011 19.0 0.0 0.012 15.6 0.0 2.3 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF87 PF01935.17 OAG41223.1 - 0.0039 17.3 1.9 0.15 12.1 0.0 2.6 1 1 0 2 2 2 1 Helicase HerA, central domain SRPRB PF09439.10 OAG41223.1 - 0.0059 16.1 0.3 0.033 13.6 0.0 2.3 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit FtsK_SpoIIIE PF01580.18 OAG41223.1 - 0.0091 15.4 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family T2SSE PF00437.20 OAG41223.1 - 0.011 14.8 0.0 0.025 13.7 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein IIGP PF05049.13 OAG41223.1 - 0.02 13.9 0.1 0.065 12.3 0.0 1.7 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) AAA_22 PF13401.6 OAG41223.1 - 0.025 14.8 0.3 0.23 11.8 0.0 2.4 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.27 OAG41223.1 - 0.026 15.1 0.4 0.13 12.7 0.0 2.1 2 1 0 2 2 2 0 ABC transporter Zeta_toxin PF06414.12 OAG41223.1 - 0.034 13.4 0.0 0.073 12.3 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin TrwB_AAD_bind PF10412.9 OAG41223.1 - 0.042 12.8 0.0 0.089 11.7 0.0 1.5 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_16 PF13191.6 OAG41223.1 - 0.064 13.6 0.8 0.19 12.1 0.1 2.2 1 1 1 2 2 2 0 AAA ATPase domain IstB_IS21 PF01695.17 OAG41223.1 - 0.067 12.9 0.1 0.17 11.6 0.1 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_29 PF13555.6 OAG41223.1 - 0.07 12.9 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF1931 PF09123.11 OAG41223.1 - 0.13 12.4 1.1 1.8 8.7 0.0 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF1931) AAA_23 PF13476.6 OAG41223.1 - 0.42 11.1 3.9 4.7 7.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain Macoilin PF09726.9 OAG41224.1 - 0.046 12.3 0.5 0.065 11.8 0.0 1.4 2 0 0 2 2 2 0 Macoilin family CENP-F_leu_zip PF10473.9 OAG41224.1 - 0.067 13.2 2.0 0.14 12.2 0.6 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_TATA_bd PF12325.8 OAG41224.1 - 0.43 10.8 5.3 0.59 10.4 0.4 2.7 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding bZIP_1 PF00170.21 OAG41224.1 - 0.89 9.7 2.3 3.6 7.7 0.2 2.7 2 1 1 3 3 3 0 bZIP transcription factor HSP70 PF00012.20 OAG41225.1 - 4.9e-06 25.0 1.6 1.4e-05 23.5 0.1 2.2 3 0 0 3 3 3 1 Hsp70 protein Amidase PF01425.21 OAG41226.1 - 1.2e-78 265.1 0.0 2.1e-78 264.3 0.0 1.4 1 1 0 1 1 1 1 Amidase Amino_oxidase PF01593.24 OAG41227.1 - 7.5e-52 177.1 0.0 1.3e-51 176.4 0.0 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Ribonuc_L-PSP PF01042.21 OAG41227.1 - 3.1e-18 65.9 0.0 7e-18 64.8 0.0 1.6 2 0 0 2 2 1 1 Endoribonuclease L-PSP NAD_binding_8 PF13450.6 OAG41227.1 - 2.6e-12 46.8 0.1 6e-12 45.6 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 OAG41227.1 - 2.9e-07 29.9 1.6 4.8e-07 29.2 1.6 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAG41227.1 - 4e-07 29.9 0.4 6e-06 26.1 1.2 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 OAG41227.1 - 2.9e-06 26.7 0.2 4.7e-06 26.0 0.2 1.2 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 OAG41227.1 - 2.6e-05 23.6 0.1 4e-05 23.0 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 OAG41227.1 - 5.3e-05 22.6 0.8 7.8e-05 22.1 0.8 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 OAG41227.1 - 9.4e-05 21.9 1.9 0.00017 21.1 1.9 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 OAG41227.1 - 0.00012 22.5 0.1 0.00035 21.1 0.1 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAG41227.1 - 0.00083 18.2 0.0 0.0027 16.5 0.3 1.6 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 OAG41227.1 - 0.0011 18.1 0.1 0.0016 17.6 0.1 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 OAG41227.1 - 0.0019 17.3 0.1 0.045 12.8 0.4 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 OAG41227.1 - 0.0036 16.6 0.0 0.041 13.1 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Omp_AT PF11557.8 OAG41227.1 - 0.028 13.4 0.0 0.044 12.7 0.0 1.2 1 0 0 1 1 1 0 Solitary outer membrane autotransporter beta-barrel domain AlaDh_PNT_C PF01262.21 OAG41227.1 - 0.035 13.4 0.1 0.06 12.6 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DUF2231 PF09990.9 OAG41228.1 - 5.6e-09 36.4 0.1 9.2e-09 35.7 0.1 1.4 1 0 0 1 1 1 1 Predicted membrane protein (DUF2231) 2OG-FeII_Oxy PF03171.20 OAG41229.1 - 1.7e-07 31.7 0.0 3.6e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 OAG41229.1 - 0.0013 19.4 0.0 0.0023 18.7 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal ThiJ_like PF17124.5 OAG41230.1 - 2.4e-61 206.9 0.0 2.6e-61 206.8 0.0 1.0 1 0 0 1 1 1 1 ThiJ/PfpI family-like DJ-1_PfpI PF01965.24 OAG41230.1 - 2.6e-10 40.3 0.0 6.4e-10 39.1 0.0 1.6 1 1 0 1 1 1 1 DJ-1/PfpI family GATase_3 PF07685.14 OAG41230.1 - 0.12 12.0 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.28 OAG41230.1 - 0.2 11.4 0.0 0.27 11.0 0.0 1.2 1 0 0 1 1 1 0 Glutamine amidotransferase class-I Sugar_tr PF00083.24 OAG41231.1 - 1.6e-75 254.7 18.8 2e-75 254.4 18.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG41231.1 - 6.6e-30 104.2 26.9 1.1e-29 103.5 26.9 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Cyclase PF04199.13 OAG41232.1 - 2.2e-13 50.6 0.1 3.1e-13 50.1 0.1 1.2 1 0 0 1 1 1 1 Putative cyclase adh_short PF00106.25 OAG41233.1 - 1.1e-31 109.9 0.0 1.5e-31 109.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG41233.1 - 1.1e-24 87.2 0.0 1.7e-24 86.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 OAG41233.1 - 0.1 12.0 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.19 OAG41233.1 - 0.14 11.5 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain KR PF08659.10 OAG41233.1 - 0.17 11.8 0.1 0.71 9.8 0.1 1.9 1 1 0 1 1 1 0 KR domain adh_short PF00106.25 OAG41234.1 - 1.5e-30 106.1 0.0 3.3e-30 105.0 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG41234.1 - 2.3e-28 99.3 0.0 6.9e-28 97.8 0.0 1.8 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Fungal_trans PF04082.18 OAG41234.1 - 1.8e-15 56.7 0.9 3.8e-15 55.6 0.9 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain FMO-like PF00743.19 OAG41234.1 - 1.1e-09 37.4 0.7 1.2e-06 27.2 0.1 2.6 3 0 0 3 3 3 2 Flavin-binding monooxygenase-like KR PF08659.10 OAG41234.1 - 0.0012 18.8 0.3 0.0044 17.0 0.0 2.1 3 0 0 3 3 3 1 KR domain Pyr_redox_2 PF07992.14 OAG41234.1 - 0.0036 16.6 2.1 0.024 13.9 0.1 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 OAG41234.1 - 0.038 13.9 0.1 0.34 10.8 0.0 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 OAG41234.1 - 0.067 12.4 0.1 0.067 12.4 0.1 2.8 4 0 0 4 4 4 0 Pyridine nucleotide-disulphide oxidoreductase Sacchrp_dh_NADP PF03435.18 OAG41234.1 - 0.19 12.0 0.3 20 5.4 0.1 2.6 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Abhydrolase_3 PF07859.13 OAG41235.1 - 8.1e-47 159.8 0.0 1e-46 159.5 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 OAG41235.1 - 2.3e-05 23.4 0.0 2.9e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase COesterase PF00135.28 OAG41235.1 - 0.0075 15.2 0.0 0.022 13.6 0.0 1.6 2 0 0 2 2 2 1 Carboxylesterase family DLH PF01738.18 OAG41235.1 - 0.072 12.6 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family Peptidase_S9 PF00326.21 OAG41235.1 - 0.11 12.0 0.0 0.42 10.0 0.0 1.8 1 1 0 1 1 1 0 Prolyl oligopeptidase family zf-3CxxC PF13695.6 OAG41236.1 - 1.1e-20 73.9 0.7 1.7e-20 73.4 0.3 1.5 2 0 0 2 2 2 1 Zinc-binding domain IR1-M PF12185.8 OAG41236.1 - 0.018 15.0 0.0 0.031 14.2 0.0 1.3 1 0 0 1 1 1 0 Nup358/RanBP2 E3 ligase domain Lipase_GDSL_2 PF13472.6 OAG41238.1 - 3.3e-18 66.7 1.7 4.7e-18 66.2 1.7 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 OAG41238.1 - 2.5e-08 34.2 0.0 3.9e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase CDH-cyt PF16010.5 OAG41239.1 - 2.8e-27 95.6 1.6 2.8e-27 95.6 1.6 1.7 1 1 1 2 2 2 1 Cytochrome domain of cellobiose dehydrogenase Cytochrom_B561 PF03188.16 OAG41239.1 - 2e-06 28.0 9.9 4.4e-06 26.9 9.9 1.6 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DOMON PF03351.17 OAG41239.1 - 9.9e-05 22.6 0.1 0.00021 21.5 0.1 1.6 1 0 0 1 1 1 1 DOMON domain DUF2427 PF10348.9 OAG41239.1 - 0.00076 19.2 2.1 0.00076 19.2 2.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) MerC PF03203.14 OAG41239.1 - 0.0061 17.0 0.9 0.0061 17.0 0.9 2.3 2 0 0 2 2 2 1 MerC mercury resistance protein DUF4079 PF13301.6 OAG41239.1 - 0.082 13.1 3.9 0.1 12.7 1.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4079) SdpI PF13630.6 OAG41239.1 - 6.7 6.9 9.8 1.1 9.4 1.8 3.1 3 1 0 3 3 3 0 SdpI/YhfL protein family PDH PF02153.17 OAG41240.1 - 2e-12 46.7 0.0 2.6e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase Ribosomal_S11 PF00411.19 OAG41241.1 - 7.3e-47 158.3 1.0 9.1e-47 158.0 1.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 CBM_25 PF03423.13 OAG41241.1 - 0.14 12.4 0.0 0.26 11.6 0.0 1.4 1 0 0 1 1 1 0 Carbohydrate binding domain (family 25) AAR2 PF05282.11 OAG41242.1 - 5e-64 216.9 0.0 8.6e-35 120.8 0.1 2.0 1 1 1 2 2 2 2 AAR2 protein Gp49 PF05973.14 OAG41242.1 - 0.13 12.5 0.1 0.79 9.9 0.0 2.0 1 1 1 2 2 2 0 Phage derived protein Gp49-like (DUF891) Ribosomal_S9 PF00380.19 OAG41243.1 - 1.5e-34 119.1 0.2 1.7e-34 119.0 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Exo70 PF03081.15 OAG41243.1 - 0.19 10.7 0.5 0.25 10.4 0.5 1.1 1 0 0 1 1 1 0 Exo70 exocyst complex subunit Ribosomal_L13 PF00572.18 OAG41244.1 - 1.9e-44 150.9 0.1 2.3e-44 150.7 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 Uricase PF01014.18 OAG41245.1 - 1.8e-80 267.7 2.6 1.3e-42 145.1 1.0 2.1 2 0 0 2 2 2 2 Uricase RICTOR_N PF14664.6 OAG41246.1 - 5e-124 414.1 0.2 8e-124 413.4 0.2 1.3 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.6 OAG41246.1 - 3.3e-36 123.2 1.6 6.2e-35 119.1 0.1 3.6 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.6 OAG41246.1 - 1.7e-35 121.7 0.1 1.3e-33 115.6 0.0 3.4 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.6 OAG41246.1 - 5.1e-28 97.1 1.4 3.4e-26 91.3 0.1 3.8 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.16 OAG41246.1 - 5e-15 55.4 10.4 1.4e-14 53.9 10.4 1.9 1 0 0 1 1 1 1 Hr1 repeat Proteasom_PSMB PF10508.9 OAG41246.1 - 0.00049 18.7 0.0 0.48 8.9 0.0 3.7 3 1 1 4 4 4 1 Proteasome non-ATPase 26S subunit Arm PF00514.23 OAG41246.1 - 0.035 14.2 0.0 0.4 10.8 0.1 2.9 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat Uds1 PF15456.6 OAG41246.1 - 0.093 12.9 5.6 0.25 11.5 5.6 1.7 1 0 0 1 1 1 0 Up-regulated During Septation LON_substr_bdg PF02190.16 OAG41247.1 - 2.4e-25 89.6 0.0 3.5e-25 89.1 0.0 1.2 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain zf-C3HC4_2 PF13923.6 OAG41247.1 - 8.2e-10 38.4 16.4 1.4e-09 37.6 16.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAG41247.1 - 2.6e-06 27.4 7.6 2.6e-06 27.4 7.6 1.9 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 OAG41247.1 - 6.8e-06 25.8 12.3 1.2e-05 25.0 12.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAG41247.1 - 1.4e-05 25.3 15.2 2.5e-05 24.5 15.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 OAG41247.1 - 1.5e-05 24.9 15.3 2.4e-05 24.2 15.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 OAG41247.1 - 0.00019 21.2 12.0 0.00041 20.1 12.0 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 OAG41247.1 - 0.00033 20.5 15.5 0.00054 19.8 15.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 OAG41247.1 - 0.00043 20.4 9.1 0.00072 19.6 9.1 1.3 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-C3HC4_4 PF15227.6 OAG41247.1 - 0.002 18.2 13.2 0.0039 17.3 13.2 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING U-box PF04564.15 OAG41247.1 - 0.008 16.3 0.1 0.017 15.3 0.1 1.6 1 0 0 1 1 1 1 U-box domain zf-rbx1 PF12678.7 OAG41247.1 - 0.057 13.7 9.6 0.12 12.6 9.6 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-P11 PF03854.14 OAG41247.1 - 0.31 10.7 9.8 0.63 9.8 9.8 1.4 1 0 0 1 1 1 0 P-11 zinc finger zf-RING_4 PF14570.6 OAG41247.1 - 0.92 9.4 16.2 0.35 10.7 12.8 2.0 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain Amidase PF01425.21 OAG41248.1 - 1.9e-52 178.8 0.0 7.1e-52 176.9 0.0 1.9 1 1 0 1 1 1 1 Amidase Glyco_hydro_43 PF04616.14 OAG41249.1 - 2.4e-71 240.4 0.4 3.1e-71 240.0 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 OAG41249.1 - 7.8e-12 45.3 0.0 1.3e-11 44.7 0.0 1.2 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain DUF1349 PF07081.11 OAG41249.1 - 0.00045 20.0 0.0 0.00088 19.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) Thioredoxin PF00085.20 OAG41250.1 - 1.7e-06 27.9 0.0 3.5e-06 26.9 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 OAG41250.1 - 0.00023 20.6 0.0 0.0003 20.2 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 OAG41250.1 - 0.0007 20.0 0.0 0.0014 19.1 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like domain PWI PF01480.17 OAG41252.1 - 4.7e-16 58.9 0.1 9.7e-16 57.9 0.1 1.6 1 0 0 1 1 1 1 PWI domain RRM_1 PF00076.22 OAG41252.1 - 0.0033 17.2 0.0 0.0075 16.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Zn_clus PF00172.18 OAG41253.1 - 0.00011 22.2 11.3 0.00038 20.5 11.3 1.9 1 1 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FIST_C PF10442.9 OAG41253.1 - 0.077 13.0 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 FIST C domain Sel1 PF08238.12 OAG41254.1 - 2.1e-12 47.3 4.7 0.0088 16.7 0.0 4.1 4 0 0 4 4 4 3 Sel1 repeat HhH-GPD PF00730.25 OAG41255.1 - 2.7e-10 40.7 0.0 7.9e-10 39.2 0.0 1.8 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 OAG41255.1 - 0.052 13.4 0.0 0.22 11.5 0.0 2.1 2 0 0 2 2 2 0 Helix-hairpin-helix motif DUF3470 PF11953.8 OAG41256.1 - 0.038 14.0 0.5 0.16 11.9 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3470) DUF4050 PF13259.6 OAG41257.1 - 2.2e-50 171.5 2.4 2.2e-50 171.5 2.4 2.0 3 0 0 3 3 3 1 Protein of unknown function (DUF4050) PGAP1 PF07819.13 OAG41259.1 - 1.9e-87 292.8 0.1 3.1e-87 292.1 0.1 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 OAG41259.1 - 1.1e-06 29.4 0.6 2.5e-06 28.3 0.1 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Palm_thioest PF02089.15 OAG41259.1 - 0.00036 20.5 0.1 0.00092 19.1 0.0 1.7 2 0 0 2 2 2 1 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.20 OAG41259.1 - 0.0013 18.4 0.0 0.0034 17.1 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAG41259.1 - 0.0036 16.6 0.0 0.0078 15.5 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF676 PF05057.14 OAG41259.1 - 0.0067 16.0 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) LCAT PF02450.15 OAG41259.1 - 0.018 14.3 0.0 0.029 13.5 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase LIDHydrolase PF10230.9 OAG41259.1 - 0.26 10.8 0.9 0.86 9.1 0.0 2.2 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase ADH_N PF08240.12 OAG41260.1 - 1.5e-20 73.1 1.5 2.7e-20 72.3 1.5 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG41260.1 - 8.4e-18 64.6 0.0 1.4e-17 63.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 OAG41260.1 - 7.9e-05 22.1 0.1 0.00013 21.4 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 OAG41260.1 - 0.00026 20.3 0.1 0.00042 19.7 0.1 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 OAG41260.1 - 0.024 14.5 0.0 0.035 14.0 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 OAG41260.1 - 0.028 14.6 0.1 0.047 13.9 0.1 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Sugar_tr PF00083.24 OAG41261.1 - 1.5e-87 294.4 18.4 1.7e-87 294.2 18.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG41261.1 - 5.4e-23 81.5 33.8 2.5e-18 66.2 21.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Pex14_N PF04695.13 OAG41261.1 - 0.05 14.2 0.6 0.12 13.0 0.3 1.8 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Cyclase PF04199.13 OAG41262.1 - 1.9e-16 60.6 0.0 2.7e-16 60.1 0.0 1.3 1 0 0 1 1 1 1 Putative cyclase Aldedh PF00171.22 OAG41263.1 - 4.3e-143 477.2 0.0 5.8e-143 476.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family ADH_N PF08240.12 OAG41264.1 - 1.3e-25 89.4 1.5 2.1e-25 88.7 1.5 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG41264.1 - 8.3e-17 61.4 0.0 1.3e-16 60.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 OAG41264.1 - 2.8e-06 27.0 0.1 9.3e-06 25.3 0.1 1.8 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 OAG41264.1 - 0.00071 20.6 0.0 0.0015 19.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 OAG41264.1 - 0.0028 17.0 0.1 0.0046 16.3 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AtuA PF07287.11 OAG41265.1 - 4.6e-128 426.9 0.2 5.4e-128 426.6 0.2 1.0 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA Mpt_N PF09176.11 OAG41265.1 - 0.032 14.4 0.2 0.094 12.9 0.0 1.9 2 0 0 2 2 2 0 Methylene-tetrahydromethanopterin dehydrogenase, N-terminal Fungal_trans PF04082.18 OAG41266.1 - 3.9e-20 72.0 0.1 8.1e-20 71.0 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG41266.1 - 8.9e-10 38.5 12.0 1.5e-09 37.8 12.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Nnf1 PF03980.14 OAG41266.1 - 0.08 13.3 1.1 0.46 10.9 0.6 2.3 2 0 0 2 2 2 0 Nnf1 MSG PF02349.15 OAG41266.1 - 1.3 9.2 5.3 2.8 8.2 5.3 1.5 1 0 0 1 1 1 0 Major surface glycoprotein bZIP_2 PF07716.15 OAG41266.1 - 2.8 8.1 7.2 6.3 7.0 7.2 1.5 1 0 0 1 1 1 0 Basic region leucine zipper Sec63 PF02889.16 OAG41267.1 - 1.8e-28 99.4 0.0 2.9e-28 98.8 0.0 1.3 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.29 OAG41267.1 - 2.9e-25 89.0 0.0 8.2e-25 87.6 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 OAG41267.1 - 6.9e-13 48.9 0.2 3.4e-12 46.7 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 OAG41267.1 - 4.8e-07 30.1 0.0 1.6e-06 28.4 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 OAG41267.1 - 0.0034 17.6 0.1 0.013 15.8 0.1 1.9 1 1 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 OAG41267.1 - 0.0078 15.8 1.0 0.034 13.7 0.0 2.4 3 0 0 3 3 3 1 UvrD/REP helicase N-terminal domain AAA_30 PF13604.6 OAG41267.1 - 0.02 14.6 0.0 0.047 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 OAG41267.1 - 0.032 14.6 0.1 0.3 11.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 OAG41267.1 - 0.035 13.2 0.0 0.077 12.0 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein HHH_5 PF14520.6 OAG41267.1 - 0.075 13.7 0.0 0.18 12.4 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix domain Helicase_RecD PF05127.14 OAG41267.1 - 0.17 11.7 0.0 0.36 10.7 0.0 1.5 1 0 0 1 1 1 0 Helicase Nuc_sug_transp PF04142.15 OAG41268.1 - 1.5e-90 303.6 6.5 3.9e-89 298.9 6.5 2.0 1 1 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 OAG41268.1 - 2.8e-05 24.3 8.5 2.8e-05 24.3 8.5 3.7 2 2 1 3 3 3 1 EamA-like transporter family UAA PF08449.11 OAG41268.1 - 0.021 14.1 11.8 0.026 13.8 1.7 2.7 2 1 0 2 2 2 0 UAA transporter family EmrE PF13536.6 OAG41268.1 - 0.051 13.2 0.3 0.051 13.2 0.3 2.8 2 1 0 2 2 2 0 Putative multidrug resistance efflux transporter HORMA PF02301.18 OAG41271.1 - 2.7e-33 115.4 0.0 1.8e-32 112.6 0.0 2.1 1 1 0 1 1 1 1 HORMA domain WD40 PF00400.32 OAG41272.1 - 4.1e-42 141.4 17.3 7.8e-06 26.5 0.2 8.0 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box PF00646.33 OAG41272.1 - 4.1e-11 42.5 0.1 1.1e-10 41.1 0.1 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 OAG41272.1 - 5.6e-11 42.2 0.3 2.6e-10 40.0 0.1 2.2 2 0 0 2 2 2 1 F-box-like ANAPC4_WD40 PF12894.7 OAG41272.1 - 7e-05 23.1 1.3 10 6.5 0.0 4.9 2 2 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 OAG41272.1 - 7.6e-05 22.7 0.1 7.1 6.7 0.0 4.6 4 1 1 5 5 5 2 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.8 OAG41272.1 - 0.00047 18.9 2.7 8 5.0 0.0 5.0 5 1 1 6 6 6 3 Nucleoporin Nup120/160 F-box_4 PF15966.5 OAG41272.1 - 0.015 15.2 0.0 0.042 13.7 0.0 1.7 1 0 0 1 1 1 0 F-box MMR_HSR1 PF01926.23 OAG41273.1 - 4e-17 62.3 0.0 6.6e-17 61.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OAG41273.1 - 5e-06 26.2 0.0 3.8e-05 23.3 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OAG41273.1 - 3.7e-05 23.7 0.0 0.00054 19.9 0.1 2.1 2 0 0 2 2 2 1 RsgA GTPase Septin PF00735.18 OAG41273.1 - 0.00011 21.6 0.0 0.00022 20.6 0.0 1.4 1 0 0 1 1 1 1 Septin FeoB_N PF02421.18 OAG41273.1 - 0.00012 21.6 0.1 0.00026 20.6 0.1 1.5 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 OAG41273.1 - 0.00028 21.0 0.1 0.019 15.0 0.1 2.6 2 0 0 2 2 2 1 Dynamin family SRPRB PF09439.10 OAG41273.1 - 0.0022 17.5 0.0 0.0048 16.4 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_29 PF13555.6 OAG41273.1 - 0.03 14.1 0.0 0.083 12.7 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain Roc PF08477.13 OAG41273.1 - 0.059 13.6 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Clat_adaptor_s PF01217.20 OAG41274.1 - 4.1e-44 150.0 0.0 7e-44 149.2 0.0 1.4 1 1 0 1 1 1 1 Clathrin adaptor complex small chain MFS_1 PF07690.16 OAG41276.1 - 1.5e-25 89.9 31.2 1.5e-25 89.9 31.2 2.4 1 1 1 2 2 2 1 Major Facilitator Superfamily OCD_Mu_crystall PF02423.15 OAG41277.1 - 2.1e-16 59.8 0.1 3.1e-14 52.6 0.0 3.7 2 1 0 3 3 3 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.20 OAG41277.1 - 1.9e-07 31.2 0.0 0.00013 22.0 0.0 3.0 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Acetyltransf_8 PF13523.6 OAG41278.1 - 4.8e-50 169.0 0.0 7.9e-50 168.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 OAG41278.1 - 0.0083 16.8 0.0 0.018 15.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain tRNA-synt_1 PF00133.22 OAG41279.1 - 6.7e-38 130.3 0.0 4.1e-29 101.3 0.0 2.6 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 OAG41279.1 - 9.1e-18 64.2 0.2 9.8e-11 41.0 0.0 2.7 3 0 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 OAG41279.1 - 4.3e-10 39.8 0.1 1e-09 38.6 0.1 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 OAG41279.1 - 1.7e-07 30.9 0.0 3.2e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Pkinase PF00069.25 OAG41280.1 - 1.9e-66 224.2 0.0 2.3e-66 223.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG41280.1 - 5e-31 107.9 0.0 7.3e-31 107.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OAG41280.1 - 0.00098 18.2 0.0 0.0015 17.6 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OAG41280.1 - 0.0017 17.8 0.0 0.0027 17.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OAG41280.1 - 0.0028 17.0 0.0 0.005 16.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like SET PF00856.28 OAG41281.1 - 1.5e-14 54.7 0.0 2.3e-14 54.1 0.0 1.3 1 0 0 1 1 1 1 SET domain DUF4267 PF14087.6 OAG41282.1 - 4e-12 46.2 1.9 4e-12 46.2 1.9 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4267) AWPM-19 PF05512.11 OAG41282.1 - 1.5 9.0 5.1 0.63 10.2 1.5 2.0 2 0 0 2 2 2 0 AWPM-19-like family HMA PF00403.26 OAG41283.1 - 6e-12 45.8 0.0 1.1e-11 44.9 0.0 1.5 1 0 0 1 1 1 1 Heavy-metal-associated domain Sod_Cu PF00080.20 OAG41283.1 - 2.7e-09 37.3 0.0 4.1e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) TPR_1 PF00515.28 OAG41284.1 - 5.3e-13 48.2 8.2 3e-06 26.8 0.0 4.8 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 OAG41284.1 - 9.7e-13 47.2 4.3 0.00018 21.4 0.0 5.0 4 1 1 5 5 5 3 Tetratricopeptide repeat PB1 PF00564.24 OAG41284.1 - 3.8e-08 33.1 0.4 7.4e-08 32.2 0.4 1.4 1 0 0 1 1 1 1 PB1 domain TPR_12 PF13424.6 OAG41284.1 - 4.1e-07 30.2 0.1 0.0016 18.7 0.0 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 OAG41284.1 - 1.5e-06 27.9 1.0 0.0011 19.0 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 OAG41284.1 - 4.3e-06 26.4 0.5 0.00048 20.0 0.0 3.4 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 OAG41284.1 - 2.1e-05 24.1 2.2 0.00014 21.4 0.1 3.2 2 1 1 3 3 3 1 TPR repeat TPR_6 PF13174.6 OAG41284.1 - 4.6e-05 23.8 0.8 17 6.3 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 OAG41284.1 - 0.00089 19.9 0.1 0.037 14.7 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 OAG41284.1 - 0.0024 18.0 0.1 0.87 9.8 0.0 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 OAG41284.1 - 0.0098 16.2 1.1 0.37 11.3 0.0 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 OAG41284.1 - 0.028 15.2 0.1 2.9 8.9 0.0 3.1 3 0 0 3 3 2 0 Tetratricopeptide repeat Imm-NTF2 PF15655.6 OAG41284.1 - 0.078 13.3 0.1 0.22 11.8 0.1 1.7 1 0 0 1 1 1 0 NTF2 fold immunity protein ArgJ PF01960.18 OAG41284.1 - 0.099 11.4 0.1 0.17 10.6 0.1 1.3 1 0 0 1 1 1 0 ArgJ family TPR_10 PF13374.6 OAG41284.1 - 0.27 11.1 2.7 16 5.6 0.1 3.6 3 1 1 4 4 4 0 Tetratricopeptide repeat Med27 PF11571.8 OAG41289.1 - 1.4e-09 38.1 0.0 3.1e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 Mediator complex subunit 27 Thioredoxin_5 PF13743.6 OAG41289.1 - 0.12 12.1 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin zf-C2H2 PF00096.26 OAG41290.1 - 0.01 16.3 0.1 0.01 16.3 0.1 3.9 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAG41290.1 - 0.25 12.3 0.0 0.25 12.3 0.0 4.6 4 0 0 4 4 4 0 C2H2-type zinc finger APH PF01636.23 OAG41291.1 - 5.1e-43 147.7 0.0 7e-43 147.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 OAG41291.1 - 2e-05 24.1 0.0 3.2e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase Kdo PF06293.14 OAG41291.1 - 0.00013 21.3 0.0 0.00051 19.5 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1679 PF07914.11 OAG41291.1 - 0.00022 20.2 0.0 0.0011 17.9 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1679) Fructosamin_kin PF03881.14 OAG41291.1 - 0.00069 18.9 0.0 0.013 14.7 0.0 2.2 1 1 0 1 1 1 1 Fructosamine kinase Choline_kinase PF01633.20 OAG41291.1 - 0.0031 17.1 0.0 0.0043 16.7 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 OAG41291.1 - 0.0081 15.8 0.0 0.14 11.7 0.0 2.1 2 0 0 2 2 2 1 RIO1 family dUTPase PF00692.19 OAG41292.1 - 3.3e-46 156.1 0.0 4.1e-46 155.8 0.0 1.1 1 0 0 1 1 1 1 dUTPase Phos_pyr_kin PF08543.12 OAG41293.1 - 1.5e-10 40.9 0.0 2.8e-10 40.0 0.0 1.4 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 OAG41293.1 - 7.2e-06 25.5 0.0 5e-05 22.7 0.0 2.1 2 0 0 2 2 2 1 pfkB family carbohydrate kinase Usp PF00582.26 OAG41293.1 - 0.077 13.5 0.5 0.18 12.3 0.0 1.8 2 0 0 2 2 2 0 Universal stress protein family PCNA_N PF00705.18 OAG41294.1 - 5.1e-54 181.4 4.8 8.7e-54 180.6 4.8 1.3 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 OAG41294.1 - 4.3e-52 175.6 0.4 2.8e-51 173.0 0.0 2.1 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.13 OAG41294.1 - 1.6e-08 34.4 0.6 2.2e-08 33.9 0.6 1.2 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.16 OAG41294.1 - 2.1e-08 33.6 2.2 3.8e-06 26.2 2.2 2.2 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Hus1 PF04005.12 OAG41294.1 - 0.00072 18.7 1.0 0.0018 17.5 0.1 1.9 2 1 0 2 2 2 1 Hus1-like protein LppA PF16708.5 OAG41294.1 - 0.0068 16.3 0.1 0.11 12.4 0.0 2.5 2 1 1 3 3 3 1 Lipoprotein confined to pathogenic Mycobacterium Vezatin PF12632.7 OAG41295.1 - 1e-54 185.8 0.1 1e-54 185.8 0.1 1.9 3 0 0 3 3 3 1 Mysoin-binding motif of peroxisomes NCOA_u2 PF16665.5 OAG41295.1 - 0.048 14.0 1.4 0.28 11.5 0.0 2.4 2 0 0 2 2 2 0 Unstructured region on nuclear receptor coactivator protein ABC_tran_CTD PF16326.5 OAG41295.1 - 0.26 11.6 1.9 0.4 11.0 0.1 2.1 2 0 0 2 2 2 0 ABC transporter C-terminal domain XhlA PF10779.9 OAG41295.1 - 6.4 7.1 5.1 10 6.4 2.3 2.3 2 0 0 2 2 2 0 Haemolysin XhlA 30K_MP_C_Ter PF11330.8 OAG41296.1 - 0.07 12.5 0.1 0.11 11.7 0.1 1.2 1 0 0 1 1 1 0 C-Terminal of 30K viral movement proteins Epimerase PF01370.21 OAG41297.1 - 1.3e-19 70.7 0.0 1.8e-19 70.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 OAG41297.1 - 8.2e-11 41.5 0.0 1.6e-10 40.6 0.0 1.5 2 0 0 2 2 2 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 OAG41297.1 - 1e-06 28.0 0.0 7.2e-06 25.2 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 OAG41297.1 - 0.00014 21.4 0.0 0.00053 19.5 0.0 1.9 1 1 1 2 2 2 1 short chain dehydrogenase GDP_Man_Dehyd PF16363.5 OAG41297.1 - 0.00035 20.1 0.0 0.00083 18.9 0.0 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase KR PF08659.10 OAG41297.1 - 0.0049 16.8 0.0 0.0074 16.2 0.0 1.3 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 OAG41297.1 - 0.05 13.9 0.0 0.12 12.6 0.0 1.7 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Arf PF00025.21 OAG41298.1 - 6.8e-74 247.1 0.1 8e-74 246.8 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 OAG41298.1 - 4.7e-14 52.6 0.0 6.1e-14 52.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 OAG41298.1 - 1.6e-11 44.0 0.0 1.9e-11 43.8 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 OAG41298.1 - 2.2e-11 43.6 1.5 2.7e-07 30.1 0.2 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 OAG41298.1 - 3.3e-11 43.0 0.0 4e-11 42.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 OAG41298.1 - 1.4e-10 40.9 0.0 1.8e-10 40.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 OAG41298.1 - 0.0003 20.9 0.0 0.00051 20.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 OAG41298.1 - 0.029 13.7 0.2 0.05 12.9 0.1 1.4 2 0 0 2 2 2 0 6-phosphofructo-2-kinase DUF4432 PF14486.6 OAG41299.1 - 0.13 11.0 0.0 0.23 10.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4432) SGT1 PF07093.11 OAG41299.1 - 0.17 10.3 0.8 0.28 9.6 0.5 1.4 2 0 0 2 2 2 0 SGT1 protein DUF676 PF05057.14 OAG41300.1 - 4.8e-50 170.1 0.0 7e-50 169.5 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 OAG41300.1 - 2.5e-07 31.6 0.3 4e-07 30.9 0.2 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Palm_thioest PF02089.15 OAG41300.1 - 6.4e-05 22.9 0.0 0.0001 22.2 0.0 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase PGAP1 PF07819.13 OAG41300.1 - 0.0043 16.8 0.0 0.015 15.0 0.0 1.8 1 1 0 1 1 1 1 PGAP1-like protein Lipase_3 PF01764.25 OAG41300.1 - 0.012 15.5 0.0 0.02 14.7 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_1 PF00561.20 OAG41300.1 - 0.09 12.4 0.2 0.27 10.8 0.2 1.8 1 1 0 1 1 1 0 alpha/beta hydrolase fold DUF915 PF06028.11 OAG41300.1 - 0.11 11.8 0.0 0.85 8.9 0.0 2.0 1 1 1 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Hydrolase_6 PF13344.6 OAG41301.1 - 3.6e-23 81.6 0.0 7.9e-23 80.5 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OAG41301.1 - 1.6e-12 47.3 0.0 1.3e-11 44.3 0.0 2.6 1 1 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 OAG41301.1 - 0.0059 16.9 0.0 4.3 7.6 0.0 2.9 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase RhoGAP PF00620.27 OAG41302.1 - 4.3e-37 127.3 0.0 6.7e-37 126.7 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain TIM21 PF08294.11 OAG41303.1 - 2.4e-31 108.6 0.0 3.2e-31 108.2 0.0 1.2 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.10 OAG41303.1 - 0.0073 16.1 0.0 0.02 14.6 0.0 1.7 1 1 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 DUF1771 PF08590.10 OAG41304.1 - 1.2e-14 54.4 14.2 2.1e-14 53.6 14.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) zf_CCCH_4 PF18345.1 OAG41304.1 - 1.3e-09 37.8 10.8 1.5e-06 28.1 3.0 3.0 2 1 0 2 2 2 2 Zinc finger domain zf-CCCH PF00642.24 OAG41304.1 - 4.3e-09 36.1 2.8 0.00075 19.3 0.4 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Smr PF01713.21 OAG41304.1 - 3.1e-08 33.9 0.0 1e-07 32.2 0.0 1.9 1 0 0 1 1 1 1 Smr domain zf-CCCH_2 PF14608.6 OAG41304.1 - 2.3e-06 27.9 5.5 0.0034 17.8 0.7 2.3 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger zf-CCCH_4 PF18044.1 OAG41304.1 - 4e-06 26.5 10.2 4.7e-05 23.1 1.0 3.1 2 1 0 2 2 2 2 CCCH-type zinc finger HBS1_N PF08938.10 OAG41304.1 - 0.00018 21.8 0.0 0.001 19.3 0.0 2.1 2 0 0 2 2 2 1 HBS1 N-terminus zf-CCCH_3 PF15663.5 OAG41304.1 - 0.0035 17.5 3.0 1.6 9.0 0.3 2.6 1 1 1 2 2 2 2 Zinc-finger containing family Torus PF16131.5 OAG41304.1 - 0.031 15.0 3.5 0.16 12.6 3.5 2.1 1 1 0 1 1 1 0 Torus domain zf-C3H1 PF10650.9 OAG41304.1 - 0.4 10.5 2.2 3.1 7.6 0.0 2.3 2 0 0 2 2 2 0 Putative zinc-finger domain SNARE_assoc PF09335.11 OAG41305.1 - 5.8e-15 55.8 5.3 5.8e-15 55.8 5.3 2.6 2 1 1 3 3 3 1 SNARE associated Golgi protein DUF2207 PF09972.9 OAG41305.1 - 0.18 10.6 2.2 0.35 9.6 2.2 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) CorA PF01544.18 OAG41306.1 - 5e-08 32.6 1.0 1e-07 31.6 1.0 1.6 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Ribosomal_L7Ae PF01248.26 OAG41307.1 - 1.7e-19 69.4 0.2 4.4e-19 68.0 0.2 1.8 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family adh_short PF00106.25 OAG41308.1 - 3e-17 62.7 0.0 2.9e-16 59.5 0.2 2.0 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG41308.1 - 4.1e-07 29.8 0.0 6e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG41308.1 - 3.5e-06 27.0 0.1 5.4e-06 26.4 0.1 1.2 1 0 0 1 1 1 1 KR domain PUFD PF16553.5 OAG41308.1 - 0.0088 16.2 0.0 0.017 15.2 0.0 1.4 1 0 0 1 1 1 1 BCORL-PCGF1-binding domain SF1-HH PF16275.5 OAG41309.1 - 6.8e-45 152.0 1.2 1.5e-44 151.0 1.2 1.6 1 0 0 1 1 1 1 Splicing factor 1 helix-hairpin domain zf-CCHC PF00098.23 OAG41309.1 - 6e-12 45.1 11.1 1.3e-05 25.0 0.8 2.4 2 0 0 2 2 2 2 Zinc knuckle KH_1 PF00013.29 OAG41309.1 - 1.5e-08 34.3 0.1 2.8e-08 33.4 0.1 1.5 1 0 0 1 1 1 1 KH domain zf-CCHC_3 PF13917.6 OAG41309.1 - 9e-07 28.8 5.4 0.0013 18.6 2.9 2.6 1 1 1 2 2 2 2 Zinc knuckle zf-CCHC_6 PF15288.6 OAG41309.1 - 0.0013 18.5 6.8 0.37 10.7 0.7 2.8 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.6 OAG41309.1 - 0.0014 18.3 5.0 0.42 10.4 0.4 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.6 OAG41309.1 - 0.014 15.2 0.5 0.014 15.2 0.5 2.4 2 0 0 2 2 2 0 Zinc knuckle Prim_Zn_Ribbon PF08273.12 OAG41309.1 - 0.23 11.8 3.0 0.72 10.2 3.0 1.8 1 0 0 1 1 1 0 Zinc-binding domain of primase-helicase DUF2076 PF09849.9 OAG41310.1 - 1.6e-08 34.9 12.3 2.1e-08 34.6 12.3 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.13 OAG41310.1 - 7.6e-06 25.9 3.9 1.1e-05 25.4 3.9 1.2 1 0 0 1 1 1 1 CHCH domain Trypan_glycop_C PF10659.9 OAG41310.1 - 0.039 14.3 0.4 0.064 13.6 0.4 1.4 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein C-terminal domain CX9C PF16860.5 OAG41310.1 - 0.052 13.6 1.0 0.087 12.8 1.0 1.3 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Nop14 PF04147.12 OAG41311.1 - 0.082 11.1 15.6 0.091 11.0 15.6 1.1 1 0 0 1 1 1 0 Nop14-like family Astro_capsid_p PF12226.8 OAG41311.1 - 1.9 7.6 15.2 0.16 11.1 10.7 1.5 2 0 0 2 2 2 0 Turkey astrovirus capsid protein SDA1 PF05285.12 OAG41311.1 - 3.8 6.8 17.8 4.5 6.6 17.8 1.3 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 OAG41311.1 - 5.6 6.2 20.8 8.6 5.6 20.8 1.3 1 0 0 1 1 1 0 BUD22 GST_N PF02798.20 OAG41312.1 - 7.2e-11 42.3 0.0 1.3e-10 41.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OAG41312.1 - 2.2e-10 40.6 0.0 3.9e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 OAG41312.1 - 3.6e-10 40.1 0.0 6e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAG41312.1 - 1.3e-09 37.9 0.0 2.2e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OAG41312.1 - 8.2e-09 35.6 0.0 2.2e-08 34.2 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 OAG41312.1 - 5.1e-08 33.1 0.0 9.7e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Pkinase PF00069.25 OAG41313.1 - 4.6e-17 62.2 0.1 1.3e-16 60.7 0.1 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG41313.1 - 1.6e-12 47.3 0.1 2.1e-11 43.6 0.1 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase HCO3_cotransp PF00955.21 OAG41314.1 - 1.4e-84 284.7 15.9 2.5e-44 152.0 7.6 2.1 1 1 0 2 2 2 2 HCO3- transporter family SUI1 PF01253.22 OAG41315.1 - 3.8e-27 94.6 3.3 7.1e-27 93.8 3.3 1.5 1 0 0 1 1 1 1 Translation initiation factor SUI1 EOS1 PF12326.8 OAG41315.1 - 1.4e-11 44.7 2.3 1.4e-11 44.7 2.3 2.1 3 0 0 3 3 3 1 N-glycosylation protein UPF0139 PF03669.13 OAG41315.1 - 0.01 15.6 1.2 0.15 12.0 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0139) MadM PF03818.13 OAG41315.1 - 0.65 9.9 5.3 3.6 7.5 0.3 2.6 2 0 0 2 2 2 0 Malonate/sodium symporter MadM subunit Tim44 PF04280.15 OAG41316.1 - 0.0074 16.4 0.1 1.8 8.6 0.0 2.3 2 0 0 2 2 2 2 Tim44-like domain zf-C2H2 PF00096.26 OAG41317.1 - 0.021 15.3 2.0 0.025 15.0 0.2 2.0 2 0 0 2 2 2 0 Zinc finger, C2H2 type DNA_pol_phi PF04931.13 OAG41317.1 - 2.2 6.3 6.7 3 5.8 6.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF2052 PF09747.9 OAG41317.1 - 5.8 7.0 10.9 0.075 13.2 1.0 2.3 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) PQ-loop PF04193.14 OAG41318.1 - 1.3e-37 127.3 10.3 1.6e-18 66.2 1.8 2.3 2 0 0 2 2 2 2 PQ loop repeat NrsF PF06532.11 OAG41318.1 - 0.0056 16.4 0.1 0.0082 15.9 0.1 1.3 1 0 0 1 1 1 1 Negative regulator of sigma F DUF1761 PF08570.10 OAG41318.1 - 0.037 14.3 0.1 0.076 13.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1761) DUF2975 PF11188.8 OAG41318.1 - 0.31 10.9 3.4 0.43 10.5 0.3 2.5 1 1 1 3 3 3 0 Protein of unknown function (DUF2975) Cytochrom_B561 PF03188.16 OAG41319.1 - 6.5e-05 23.1 8.5 0.00021 21.4 8.5 1.9 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF2057 PF09829.9 OAG41319.1 - 0.011 15.9 1.5 0.018 15.2 1.5 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) COX14 PF14880.6 OAG41319.1 - 0.065 13.1 0.2 0.36 10.7 0.1 2.4 2 0 0 2 2 2 0 Cytochrome oxidase c assembly Cation_efflux PF01545.21 OAG41319.1 - 0.31 10.7 4.3 0.79 9.4 4.3 1.7 1 1 0 1 1 1 0 Cation efflux family ABA_WDS PF02496.16 OAG41319.1 - 0.41 11.2 4.2 35 5.0 1.0 3.4 2 1 1 3 3 3 0 ABA/WDS induced protein Tcp11 PF05794.13 OAG41322.1 - 1.6e-72 245.0 0.5 1.6e-72 245.0 0.5 2.6 3 0 0 3 3 3 1 T-complex protein 11 Pec_lyase_N PF04431.13 OAG41322.1 - 8.5 6.7 8.4 0.66 10.3 0.7 2.8 2 0 0 2 2 2 0 Pectate lyase, N terminus DLH PF01738.18 OAG41323.1 - 3.6e-12 46.3 3.6 1.9e-11 43.9 3.6 2.0 1 1 0 1 1 1 1 Dienelactone hydrolase family GAF_2 PF13185.6 OAG41324.1 - 1.1e-10 41.9 0.0 1.6e-10 41.4 0.0 1.3 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 OAG41324.1 - 5.6e-08 33.5 0.0 8.9e-08 32.8 0.0 1.4 1 1 0 1 1 1 1 GAF domain GAF_3 PF13492.6 OAG41324.1 - 0.00037 20.8 0.0 0.00062 20.1 0.0 1.3 1 0 0 1 1 1 1 GAF domain DEAD PF00270.29 OAG41325.1 - 4.3e-35 121.1 0.5 1.7e-34 119.1 0.2 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAG41325.1 - 2.7e-23 82.4 0.2 1e-22 80.5 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 OAG41325.1 - 0.037 13.8 0.0 0.067 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain CMS1 PF14617.6 OAG41325.1 - 0.073 12.4 0.1 0.17 11.2 0.1 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit ATPgrasp_N PF18130.1 OAG41325.1 - 0.12 12.9 0.0 1.3 9.6 0.0 2.7 2 0 0 2 2 2 0 ATP-grasp N-terminal domain AAA_22 PF13401.6 OAG41325.1 - 0.19 12.0 0.5 0.92 9.8 0.5 2.1 1 1 0 1 1 1 0 AAA domain Tachykinin PF02202.16 OAG41325.1 - 0.52 10.3 2.6 25 5.1 0.3 3.0 2 0 0 2 2 2 0 Tachykinin family FCH PF00611.23 OAG41326.1 - 3.9e-23 81.5 4.0 4.1e-23 81.5 0.2 2.6 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.6 OAG41326.1 - 7e-23 80.2 0.4 2.3e-12 46.6 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 OAG41326.1 - 1.1e-17 63.4 0.1 2.1e-09 36.8 0.0 2.4 2 0 0 2 2 2 2 SH3 domain C1_1 PF00130.22 OAG41326.1 - 0.0012 18.7 0.1 0.002 18.0 0.1 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_3 PF08239.11 OAG41326.1 - 0.0056 16.9 0.0 0.25 11.6 0.0 2.7 2 0 0 2 2 2 1 Bacterial SH3 domain SH3_10 PF17902.1 OAG41326.1 - 0.03 14.4 0.0 1.2 9.2 0.0 2.7 2 0 0 2 2 2 0 SH3 domain SH3_2 PF07653.17 OAG41326.1 - 0.081 12.6 0.0 0.19 11.5 0.0 1.7 1 0 0 1 1 1 0 Variant SH3 domain Ribosomal_L36e PF01158.18 OAG41326.1 - 0.12 12.7 3.2 0.13 12.5 0.2 2.6 2 0 0 2 2 2 0 Ribosomal protein L36e Pyr_excise PF03013.14 OAG41326.1 - 0.28 11.1 5.9 0.38 10.7 2.0 2.4 2 0 0 2 2 2 0 Pyrimidine dimer DNA glycosylase USP8_interact PF08941.10 OAG41326.1 - 7.8 6.3 6.9 57 3.5 0.0 3.3 3 0 0 3 3 3 0 USP8 interacting Na_Ca_ex PF01699.24 OAG41327.1 - 0.031 14.2 0.1 0.045 13.7 0.1 1.2 1 0 0 1 1 1 0 Sodium/calcium exchanger protein p450 PF00067.22 OAG41328.1 - 4e-39 134.6 0.0 9.3e-39 133.4 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 Ras PF00071.22 OAG41329.1 - 2.1e-06 27.4 0.0 0.00038 20.1 0.0 2.2 1 1 1 2 2 2 2 Ras family AAA_16 PF13191.6 OAG41329.1 - 0.0096 16.3 0.0 0.012 16.0 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain Roc PF08477.13 OAG41329.1 - 0.011 15.9 0.0 0.018 15.2 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_18 PF13238.6 OAG41329.1 - 0.011 16.2 0.0 0.017 15.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 OAG41329.1 - 0.014 15.3 0.3 0.13 12.1 0.1 2.0 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea ATPase PF06745.13 OAG41329.1 - 0.015 14.7 0.0 0.019 14.3 0.0 1.1 1 0 0 1 1 1 0 KaiC cobW PF02492.19 OAG41329.1 - 0.029 14.0 0.0 0.04 13.5 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.22 OAG41329.1 - 0.046 12.9 0.0 0.061 12.5 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_22 PF13401.6 OAG41329.1 - 0.048 13.9 0.0 0.066 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 OAG41329.1 - 0.053 12.5 0.0 0.068 12.1 0.0 1.1 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF3102 PF11300.8 OAG41329.1 - 0.057 13.7 0.0 0.087 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3102) Septin PF00735.18 OAG41329.1 - 0.064 12.5 0.0 0.08 12.2 0.0 1.1 1 0 0 1 1 1 0 Septin AAA_24 PF13479.6 OAG41329.1 - 0.091 12.5 0.1 0.15 11.7 0.1 1.3 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 OAG41329.1 - 0.12 12.1 0.2 0.5 10.1 0.1 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain ABC_tran PF00005.27 OAG41329.1 - 0.14 12.7 0.0 0.2 12.2 0.0 1.2 1 0 0 1 1 1 0 ABC transporter Zeta_toxin PF06414.12 OAG41329.1 - 0.15 11.3 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin Abhydrolase_3 PF07859.13 OAG41330.1 - 2.5e-21 76.5 0.0 7.2e-19 68.5 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 OAG41330.1 - 0.0011 17.9 0.0 0.032 13.1 0.0 2.1 1 1 1 2 2 2 1 Steryl acetyl hydrolase Abhydrolase_6 PF12697.7 OAG41330.1 - 0.0094 16.6 0.7 0.0094 16.6 0.7 2.3 1 1 1 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG41330.1 - 0.014 14.7 0.0 0.028 13.7 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Thioesterase PF00975.20 OAG41330.1 - 0.056 13.6 0.0 0.095 12.8 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain COesterase PF00135.28 OAG41330.1 - 0.11 11.3 0.2 0.2 10.5 0.0 1.4 2 0 0 2 2 2 0 Carboxylesterase family Peptidase_S9 PF00326.21 OAG41330.1 - 0.18 11.3 0.0 0.58 9.6 0.0 1.7 2 0 0 2 2 2 0 Prolyl oligopeptidase family Pkinase PF00069.25 OAG41331.1 - 8.8e-13 48.2 0.0 1.3e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG41331.1 - 4.1e-08 32.8 0.0 6.6e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAG41331.1 - 0.00019 20.3 0.0 0.00025 19.9 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Myb_DNA-bind_7 PF15963.5 OAG41332.1 - 0.18 11.7 0.0 0.68 9.9 0.0 1.9 2 0 0 2 2 2 0 Myb DNA-binding like FAD_binding_2 PF00890.24 OAG41333.1 - 2.8e-81 273.7 0.3 3.3e-81 273.5 0.3 1.0 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAG41333.1 - 5.6e-07 29.5 0.8 1.2e-06 28.3 0.7 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 OAG41333.1 - 1.5e-06 27.8 0.2 1.5e-05 24.6 0.2 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG41333.1 - 0.0008 18.7 0.1 0.086 12.1 0.1 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAG41333.1 - 0.0093 15.2 0.0 0.031 13.5 0.1 1.8 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 OAG41333.1 - 0.021 14.1 0.0 0.041 13.1 0.0 1.4 2 0 0 2 2 2 0 FAD binding domain DUF1907 PF08925.11 OAG41335.1 - 2.7e-93 312.5 0.1 5.9e-72 242.5 0.0 2.8 2 1 0 2 2 2 2 Domain of Unknown Function (DUF1907) Sugar_tr PF00083.24 OAG41336.1 - 7.8e-90 301.9 18.9 9.2e-90 301.7 18.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG41336.1 - 2.6e-36 125.3 53.5 1.3e-29 103.2 28.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 OAG41336.1 - 4.1e-06 25.5 1.2 4.1e-06 25.5 1.2 2.5 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 OAG41336.1 - 2.5e-05 23.8 2.6 2.5e-05 23.8 2.6 3.1 4 0 0 4 4 4 1 Uncharacterised MFS-type transporter YbfB DUF5413 PF17434.2 OAG41336.1 - 0.33 11.3 8.3 0.89 9.9 4.8 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5413) TMEM43 PF07787.12 OAG41336.1 - 2.9 7.2 5.4 0.28 10.5 0.2 1.9 2 0 0 2 2 2 0 Transmembrane protein 43 AA_permease PF00324.21 OAG41337.1 - 2.9e-104 349.3 42.4 3.8e-104 349.0 42.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAG41337.1 - 2.2e-28 99.3 45.8 2.8e-28 98.9 45.8 1.1 1 0 0 1 1 1 1 Amino acid permease Exo_endo_phos PF03372.23 OAG41338.1 - 7.7e-14 51.8 0.1 1.2e-13 51.2 0.1 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-GRF PF06839.12 OAG41338.1 - 0.00055 20.0 6.5 0.00055 20.0 6.5 2.2 2 1 0 2 2 2 1 GRF zinc finger Exo_endo_phos_2 PF14529.6 OAG41338.1 - 0.0039 17.0 0.0 1.2 9.0 0.0 2.4 2 0 0 2 2 2 2 Endonuclease-reverse transcriptase SHR-BD PF06650.12 OAG41339.1 - 6.1e-98 327.5 0.0 1.1e-94 316.8 0.0 2.7 2 0 0 2 2 2 2 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13_mid_rpt PF16910.5 OAG41339.1 - 1.9e-94 315.5 16.6 5e-91 304.3 2.9 6.4 5 1 0 5 5 5 2 Repeating coiled region of VPS13 VPS13 PF16908.5 OAG41339.1 - 4.9e-80 268.7 0.8 6e-79 265.2 0.0 3.2 4 0 0 4 4 4 1 Vacuolar sorting-associated protein 13, N-terminal VPS13_C PF16909.5 OAG41339.1 - 7.2e-75 250.7 4.1 9.7e-71 237.2 0.4 2.9 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal Chorein_N PF12624.7 OAG41339.1 - 1.1e-40 138.4 0.1 4.3e-40 136.4 0.1 2.2 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 OAG41339.1 - 8.8e-07 29.2 0.2 1.1e-05 25.7 0.0 2.8 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain DUF896 PF05979.12 OAG41339.1 - 0.017 15.0 4.3 1.9 8.4 0.2 3.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF896) DUF3040 PF11239.8 OAG41339.1 - 0.082 13.2 0.7 0.28 11.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) TFIIA PF03153.13 OAG41340.1 - 0.00037 20.6 20.2 0.00049 20.2 20.2 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit YabA PF06156.13 OAG41340.1 - 3 8.5 8.9 0.12 13.1 0.8 2.4 2 0 0 2 2 2 0 Initiation control protein YabA GAS PF13851.6 OAG41340.1 - 6.2 6.1 13.2 0.12 11.7 3.9 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding SUIM_assoc PF16619.5 OAG41340.1 - 9.2 6.4 21.0 6.1 7.0 7.3 3.0 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Pkinase_Tyr PF07714.17 OAG41344.1 - 4.5e-11 42.5 0.0 1.1e-09 38.0 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OAG41344.1 - 5.9e-11 42.2 0.0 1.2e-10 41.3 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 OAG41344.1 - 0.034 13.5 0.0 0.069 12.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 OAG41344.1 - 0.087 12.4 0.0 0.2 11.3 0.0 1.7 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 TLP1_add_C PF18313.1 OAG41346.1 - 1.9e-23 82.2 0.1 5.7e-23 80.7 0.0 1.8 2 0 0 2 2 2 1 Thiolase-like protein type 1 additional C-terminal domain Mannosidase_ig PF17786.1 OAG41349.1 - 3.2e-18 66.1 0.2 3.2e-18 66.1 0.2 2.5 3 0 0 3 3 3 1 Mannosidase Ig/CBM-like domain Ig_mannosidase PF17753.1 OAG41349.1 - 7.5e-07 28.8 0.2 1.7e-06 27.6 0.2 1.6 1 0 0 1 1 1 1 Ig-fold domain Glyco_hydro_2 PF00703.21 OAG41349.1 - 2.7e-06 28.0 0.5 1.2e-05 26.0 0.0 2.4 3 0 0 3 3 3 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.18 OAG41349.1 - 5.9e-05 23.0 0.0 0.00015 21.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain GFA PF04828.14 OAG41350.1 - 0.0041 17.4 0.4 0.076 13.4 0.6 2.5 3 0 0 3 3 3 1 Glutathione-dependent formaldehyde-activating enzyme FAD_binding_2 PF00890.24 OAG41351.1 - 3.1e-38 132.0 0.0 4e-38 131.6 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAG41351.1 - 0.00021 21.0 0.1 0.01 15.5 0.0 2.5 2 1 1 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 OAG41351.1 - 0.0015 19.0 0.0 0.32 11.6 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAG41351.1 - 0.0023 17.2 0.1 0.043 13.0 0.1 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAG41351.1 - 0.0038 16.0 0.1 1 8.0 0.0 2.9 3 0 0 3 3 3 2 HI0933-like protein NAD_binding_9 PF13454.6 OAG41351.1 - 0.033 14.2 0.1 0.69 9.9 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pkinase PF00069.25 OAG41352.1 - 3.5e-51 174.1 0.0 5.6e-51 173.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG41352.1 - 2.2e-24 86.1 0.0 1.5e-23 83.4 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 OAG41352.1 - 0.016 14.2 0.0 0.023 13.7 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.22 OAG41352.1 - 0.14 11.7 2.2 0.18 11.4 0.0 2.3 3 0 0 3 3 3 0 RIO1 family Cupin_7 PF12973.7 OAG41353.1 - 9.3e-08 31.9 0.1 2.4e-07 30.6 0.0 1.7 2 0 0 2 2 2 1 ChrR Cupin-like domain Baculo_PEP_C PF04513.12 OAG41355.1 - 0.021 14.9 24.3 0.17 11.9 13.1 2.9 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus HATPase_c PF02518.26 OAG41356.1 - 5.6e-32 110.6 0.0 2.1e-31 108.7 0.0 2.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 OAG41356.1 - 9.6e-22 77.3 0.5 2.2e-21 76.1 0.1 1.9 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 OAG41356.1 - 6.5e-20 70.9 0.0 2e-19 69.4 0.0 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.6 OAG41356.1 - 9.4e-14 51.9 0.3 3.2e-13 50.2 0.0 2.1 2 0 0 2 2 1 1 GAF domain AAA_16 PF13191.6 OAG41356.1 - 2.3e-11 44.4 0.0 8.9e-11 42.5 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain GAF_3 PF13492.6 OAG41356.1 - 5.6e-08 33.2 0.0 1.3e-07 32.0 0.0 1.6 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 OAG41356.1 - 4.4e-07 30.6 0.1 1.5e-06 28.9 0.1 1.9 1 0 0 1 1 1 1 GAF domain Pkinase PF00069.25 OAG41356.1 - 2.7e-05 23.7 0.0 5.1e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain HATPase_c_3 PF13589.6 OAG41356.1 - 0.00013 21.8 0.0 0.0011 18.8 0.0 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Pkinase_Tyr PF07714.17 OAG41356.1 - 0.0022 17.3 0.0 0.0057 16.0 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase AAA_30 PF13604.6 OAG41356.1 - 0.031 14.0 0.0 0.13 12.0 0.0 2.0 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 OAG41356.1 - 0.14 12.1 0.0 0.57 10.1 0.0 2.0 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Thioredoxin_4 PF13462.6 OAG41356.1 - 2.2 8.4 5.7 0.31 11.2 0.7 2.2 2 0 0 2 2 2 0 Thioredoxin CFEM PF05730.11 OAG41357.1 - 3.6e-05 23.8 6.2 3.6e-05 23.8 6.2 2.5 2 0 0 2 2 2 1 CFEM domain Tme5_EGF_like PF09064.10 OAG41357.1 - 0.081 12.8 0.9 0.25 11.3 0.9 1.8 1 0 0 1 1 1 0 Thrombomodulin like fifth domain, EGF-like TIL PF01826.17 OAG41357.1 - 8.1 6.8 10.8 0.27 11.5 3.4 2.3 2 0 0 2 2 2 0 Trypsin Inhibitor like cysteine rich domain 5-FTHF_cyc-lig PF01812.20 OAG41358.1 - 4.5e-16 59.2 0.0 5.5e-16 59.0 0.0 1.1 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family MFS_1 PF07690.16 OAG41359.1 - 7.7e-30 104.0 37.6 1e-29 103.6 28.8 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG41359.1 - 3.1e-09 36.2 8.6 3.1e-09 36.2 8.6 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter Cep3 PF16846.5 OAG41359.1 - 0.012 14.1 0.2 0.023 13.2 0.2 1.4 1 0 0 1 1 1 0 Centromere DNA-binding protein complex CBF3 subunit B p450 PF00067.22 OAG41360.1 - 4.9e-47 160.7 0.0 6.2e-47 160.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Aldedh PF00171.22 OAG41361.1 - 1.2e-139 465.9 0.0 1.3e-139 465.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Wtap PF17098.5 OAG41361.1 - 0.38 10.7 1.6 0.71 9.8 1.6 1.4 1 0 0 1 1 1 0 WTAP/Mum2p family Glyoxalase PF00903.25 OAG41362.1 - 3.5e-11 43.4 0.0 5.4e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 OAG41362.1 - 1.6e-09 38.0 0.0 2.2e-09 37.6 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 OAG41362.1 - 0.00013 22.8 0.0 0.00026 21.7 0.0 1.5 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_3 PF13468.6 OAG41362.1 - 0.0067 16.6 0.0 0.019 15.1 0.0 1.7 1 1 0 1 1 1 1 Glyoxalase-like domain PALP PF00291.25 OAG41363.1 - 1.8e-63 214.7 0.0 2.1e-63 214.5 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Ribonuc_L-PSP PF01042.21 OAG41364.1 - 1.2e-32 112.5 0.0 1.4e-32 112.2 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP DAO PF01266.24 OAG41365.1 - 1.1e-44 153.5 0.2 1.3e-44 153.3 0.2 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 OAG41365.1 - 0.00047 19.5 0.0 0.00084 18.6 0.0 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 OAG41365.1 - 0.00055 20.1 0.1 0.0013 18.9 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 OAG41365.1 - 0.011 15.0 0.0 0.096 11.9 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG41365.1 - 0.013 14.7 0.0 0.57 9.3 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.24 OAG41365.1 - 0.043 12.9 0.2 0.19 10.8 0.2 1.9 1 1 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 OAG41365.1 - 0.12 11.0 0.0 3.6 6.2 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Aldedh PF00171.22 OAG41366.1 - 2.1e-153 511.2 0.0 2.4e-153 511.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Pyr_redox_3 PF13738.6 OAG41367.1 - 1.6e-16 60.4 0.0 7.7e-16 58.2 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 OAG41367.1 - 3.5e-15 55.4 0.0 1.8e-14 53.1 0.0 1.8 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 OAG41367.1 - 4.8e-11 42.4 0.0 7.9e-10 38.4 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG41367.1 - 8.8e-06 25.9 0.0 2.5e-05 24.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 OAG41367.1 - 3.6e-05 23.1 0.0 0.0002 20.7 0.0 2.0 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 OAG41367.1 - 0.00012 22.1 1.4 0.038 14.0 0.4 3.4 2 1 0 2 2 2 1 FAD-NAD(P)-binding 2-Hacid_dh_C PF02826.19 OAG41367.1 - 0.0032 16.8 0.3 0.038 13.4 0.0 2.3 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 OAG41367.1 - 0.0097 15.2 0.1 1.1 8.4 0.1 2.3 1 1 1 2 2 2 2 FAD binding domain HI0933_like PF03486.14 OAG41367.1 - 0.1 11.3 0.3 2.7 6.6 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein AA_permease_2 PF13520.6 OAG41368.1 - 1e-57 195.9 56.7 1.3e-57 195.6 56.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAG41368.1 - 1.6e-24 86.3 44.9 2.2e-24 85.9 44.9 1.1 1 0 0 1 1 1 1 Amino acid permease Ribonuc_L-PSP PF01042.21 OAG41369.1 - 8.5e-35 119.4 0.1 9.6e-35 119.2 0.1 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP adh_short_C2 PF13561.6 OAG41370.1 - 3.8e-59 200.1 1.6 4.5e-59 199.9 1.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG41370.1 - 6.3e-44 149.8 0.9 7.8e-44 149.5 0.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG41370.1 - 2.9e-09 37.1 0.6 4.6e-09 36.4 0.6 1.3 1 0 0 1 1 1 1 KR domain RIX1 PF08167.12 OAG41370.1 - 0.081 12.7 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 rRNA processing/ribosome biogenesis 3HCDH_N PF02737.18 OAG41370.1 - 0.1 12.5 0.1 0.21 11.5 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Fungal_trans_2 PF11951.8 OAG41371.1 - 2.2e-27 95.9 4.8 1.1e-26 93.6 4.8 2.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG41371.1 - 9.9e-08 32.0 9.7 1.8e-07 31.2 9.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAG41371.1 - 0.00037 19.6 0.0 0.00096 18.3 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF4140 PF13600.6 OAG41371.1 - 0.043 14.3 1.2 14 6.2 0.4 3.5 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) CENP-F_leu_zip PF10473.9 OAG41371.1 - 0.095 12.7 0.8 0.24 11.4 0.8 1.7 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MRFAP1 PF15155.6 OAG41371.1 - 0.39 11.2 5.7 0.18 12.3 0.9 2.7 3 0 0 3 3 3 0 MORF4 family-associated protein1 MFS_1 PF07690.16 OAG41372.1 - 7.9e-37 127.0 73.8 3.6e-27 95.2 47.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily zf-LITAF-like PF10601.9 OAG41373.1 - 2.7e-24 85.2 5.4 3.5e-24 84.8 5.4 1.2 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain Zn-ribbon_8 PF09723.10 OAG41373.1 - 0.055 13.6 0.3 0.7 10.1 0.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain zf-ISL3 PF14690.6 OAG41373.1 - 0.088 13.5 5.0 1 10.0 0.8 2.3 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 C1_2 PF03107.16 OAG41374.1 - 0.0012 19.1 2.2 0.0012 19.1 2.2 5.0 5 1 0 5 5 5 3 C1 domain Phage_Coat_B PF05356.11 OAG41374.1 - 0.13 12.2 1.3 0.33 10.9 0.1 2.0 2 0 0 2 2 2 0 Phage Coat protein B DUF4078 PF13300.6 OAG41375.1 - 1.1e-29 102.6 14.9 1.1e-29 102.6 14.9 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF4078) Fungal_trans PF04082.18 OAG41376.1 - 1.4e-14 53.8 0.2 8.2e-14 51.3 0.1 2.0 1 1 1 2 2 2 1 Fungal specific transcription factor domain Romo1 PF10247.9 OAG41377.1 - 0.025 14.9 0.6 3.4 8.1 0.2 2.2 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 DUF438 PF04282.13 OAG41378.1 - 0.078 12.9 0.0 10 6.2 0.1 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF438) BTB PF00651.31 OAG41379.1 - 0.006 16.8 0.0 0.0092 16.2 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain dCache_3 PF14827.6 OAG41379.1 - 0.12 12.0 0.0 0.14 11.7 0.0 1.1 1 0 0 1 1 1 0 Double sensory domain of two-component sensor kinase Sugar_tr PF00083.24 OAG41380.1 - 1.3e-100 337.4 27.3 1.5e-100 337.2 27.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG41380.1 - 1.6e-32 112.8 55.8 1.7e-27 96.3 32.1 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily NUDIX PF00293.28 OAG41381.1 - 7.7e-13 48.6 0.1 1.9e-12 47.3 0.0 1.6 2 0 0 2 2 2 1 NUDIX domain DUF1932 PF09130.11 OAG41382.1 - 0.065 13.2 0.0 0.23 11.5 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1932) Helo_like_N PF17111.5 OAG41383.1 - 1.6e-06 27.6 0.5 2.9e-06 26.8 0.5 1.3 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins SesA PF17107.5 OAG41383.1 - 9.6e-05 22.6 0.7 0.00015 21.9 0.7 1.3 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases Ank_4 PF13637.6 OAG41383.1 - 0.00019 21.9 0.0 0.61 10.7 0.0 3.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OAG41383.1 - 0.00022 21.8 0.0 0.011 16.3 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OAG41383.1 - 0.0066 16.9 0.0 59 4.7 0.0 4.0 3 0 0 3 3 3 0 Ankyrin repeat Ank_5 PF13857.6 OAG41383.1 - 0.099 13.0 0.3 13 6.2 0.0 3.5 4 0 0 4 4 4 0 Ankyrin repeats (many copies) PEP-utilisers_N PF05524.13 OAG41383.1 - 1.5 9.0 3.5 42 4.4 0.0 2.9 3 0 0 3 3 3 0 PEP-utilising enzyme, N-terminal NmrA PF05368.13 OAG41384.1 - 2.3e-06 27.4 0.1 2.9e-06 27.0 0.1 1.4 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG41384.1 - 3.1e-06 27.2 0.0 6e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 OAG41384.1 - 0.00043 19.8 0.0 0.00071 19.1 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG41384.1 - 0.0022 17.6 0.1 0.0044 16.6 0.0 1.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 OAG41384.1 - 0.0044 16.5 0.0 0.01 15.3 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family CoA_binding_2 PF13380.6 OAG41384.1 - 0.031 14.8 0.0 0.34 11.4 0.0 2.5 2 1 0 2 2 2 0 CoA binding domain HEM4 PF02602.15 OAG41384.1 - 0.077 12.3 0.3 0.16 11.3 0.1 1.5 2 0 0 2 2 2 0 Uroporphyrinogen-III synthase HemD RSN1_7TM PF02714.15 OAG41385.1 - 3.6e-74 249.5 23.8 3.6e-74 249.5 23.8 1.6 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 OAG41385.1 - 1.2e-41 142.9 0.0 1.8e-41 142.3 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 OAG41385.1 - 1.1e-37 129.2 1.0 4.3e-37 127.3 1.0 2.1 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport SID-1_RNA_chan PF13965.6 OAG41385.1 - 0.0089 14.5 0.8 0.0089 14.5 0.8 1.8 1 1 0 2 2 2 1 dsRNA-gated channel SID-1 GrpB PF04229.14 OAG41386.1 - 3.6e-38 131.3 0.0 4.2e-38 131.0 0.0 1.0 1 0 0 1 1 1 1 GrpB protein HET PF06985.11 OAG41387.1 - 2.4e-27 96.1 0.1 4.7e-27 95.1 0.1 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) UCH PF00443.29 OAG41388.1 - 3.7e-36 124.9 0.1 1.9e-31 109.5 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OAG41388.1 - 4.2e-11 43.0 0.1 8.7e-11 42.0 0.1 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase CNOT1_TTP_bind PF16417.5 OAG41388.1 - 0.14 11.3 0.1 0.23 10.6 0.1 1.3 1 0 0 1 1 1 0 CCR4-NOT transcription complex subunit 1 TTP binding domain Arginosuc_synth PF00764.19 OAG41389.1 - 6.9e-147 489.8 0.0 7.9e-147 489.6 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 OAG41389.1 - 0.026 14.0 0.1 0.07 12.6 0.0 1.7 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC Hepsin-SRCR PF09272.10 OAG41389.1 - 0.12 12.9 0.0 0.23 12.0 0.0 1.4 1 0 0 1 1 1 0 Hepsin, SRCR domain F_bP_aldolase PF01116.20 OAG41390.1 - 5.3e-92 308.3 0.1 5.9e-92 308.1 0.1 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Oxysterol_BP PF01237.18 OAG41391.1 - 4.1e-61 206.9 5.2 3.1e-53 180.9 0.0 2.0 1 1 1 2 2 2 2 Oxysterol-binding protein GST_N PF02798.20 OAG41392.1 - 1.1e-18 67.4 0.0 2.2e-18 66.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 OAG41392.1 - 2.3e-14 53.6 0.0 6.3e-14 52.2 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OAG41392.1 - 7.2e-14 51.8 0.0 1.1e-13 51.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 OAG41392.1 - 1.3e-09 38.3 0.0 2.5e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 OAG41392.1 - 1.9e-08 34.4 0.0 3.9e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OAG41392.1 - 0.00033 20.6 0.1 0.00094 19.2 0.1 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain TPR_19 PF14559.6 OAG41393.1 - 0.045 14.3 0.0 14 6.3 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 OAG41393.1 - 0.057 14.3 1.6 33 5.7 0.0 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat DNA_alkylation PF08713.11 OAG41393.1 - 0.11 12.2 0.0 0.26 10.9 0.0 1.6 1 0 0 1 1 1 0 DNA alkylation repair enzyme Spectrin_like PF18373.1 OAG41393.1 - 0.14 12.3 0.1 22 5.2 0.1 2.5 2 0 0 2 2 2 0 Spectrin like domain CUE PF02845.16 OAG41394.1 - 3e-05 23.6 0.0 5.1e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 CUE domain DUF1296 PF06972.11 OAG41394.1 - 0.097 12.8 0.4 0.21 11.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1296) Pyr_redox_2 PF07992.14 OAG41395.1 - 4.1e-42 144.4 0.0 4.9e-42 144.2 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAG41395.1 - 3e-09 37.3 0.0 9.3e-07 29.3 0.0 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG41395.1 - 0.017 14.4 0.0 7.3 5.7 0.0 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG41395.1 - 0.04 14.2 0.0 5.1 7.4 0.0 3.2 3 1 0 3 3 3 0 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 OAG41395.1 - 0.061 13.3 0.1 6.1 6.8 0.0 2.9 2 1 1 3 3 3 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 OAG41395.1 - 0.064 12.3 0.0 4.3 6.3 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.12 OAG41395.1 - 0.078 12.0 0.0 3.3 6.7 0.0 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_binding_3 PF01494.19 OAG41395.1 - 0.24 10.6 0.7 7.5 5.7 0.1 2.8 3 0 0 3 3 3 0 FAD binding domain MARVEL PF01284.23 OAG41397.1 - 0.0078 16.2 5.1 0.011 15.8 5.1 1.2 1 0 0 1 1 1 1 Membrane-associating domain ERCC4 PF02732.15 OAG41398.1 - 1.2e-26 93.8 0.1 1.9e-26 93.1 0.1 1.4 1 0 0 1 1 1 1 ERCC4 domain HHH_8 PF14716.6 OAG41398.1 - 0.0035 17.7 0.0 0.061 13.7 0.0 2.4 2 0 0 2 2 2 1 Helix-hairpin-helix domain p450 PF00067.22 OAG41399.1 - 1.1e-58 199.1 0.0 1.8e-58 198.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 CPDase PF07823.11 OAG41400.1 - 4.5e-30 104.9 0.0 5.1e-30 104.7 0.0 1.0 1 0 0 1 1 1 1 Cyclic phosphodiesterase-like protein 2_5_RNA_ligase2 PF13563.6 OAG41400.1 - 0.00032 20.6 0.1 0.14 12.0 0.0 2.1 1 1 1 2 2 2 2 2'-5' RNA ligase superfamily CHZ PF09649.10 OAG41401.1 - 0.0026 17.2 1.9 0.0056 16.1 1.9 1.6 1 0 0 1 1 1 1 Histone chaperone domain CHZ Hva1_TUDOR PF11160.8 OAG41402.1 - 3e-15 56.1 5.0 3e-15 56.1 5.0 3.1 2 1 1 3 3 3 1 Hypervirulence associated proteins TUDOR domain AT_hook PF02178.19 OAG41402.1 - 2.3 8.4 8.9 0.34 10.9 2.7 3.1 2 0 0 2 2 2 0 AT hook motif SLAC1 PF03595.17 OAG41403.1 - 4e-78 262.9 39.2 4.5e-78 262.8 39.2 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Haem_degrading PF03928.14 OAG41404.1 - 2.1e-25 89.1 0.1 2.5e-25 88.8 0.1 1.1 1 0 0 1 1 1 1 Haem-degrading Fungal_trans_2 PF11951.8 OAG41406.1 - 2e-11 43.4 0.1 3e-11 42.8 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short_C2 PF13561.6 OAG41407.1 - 6.6e-52 176.4 2.3 7.6e-52 176.2 2.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG41407.1 - 1e-44 152.4 2.8 1.3e-44 152.0 2.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG41407.1 - 1.3e-07 31.8 0.8 1.7e-07 31.3 0.8 1.1 1 0 0 1 1 1 1 KR domain AdoHcyase_NAD PF00670.21 OAG41407.1 - 0.002 18.2 0.9 0.0028 17.7 0.9 1.2 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Egh16-like PF11327.8 OAG41407.1 - 0.014 15.8 0.7 0.023 15.1 0.7 1.3 1 0 0 1 1 1 0 Egh16-like virulence factor YjeF_N PF03853.15 OAG41407.1 - 0.016 15.1 0.3 0.029 14.3 0.3 1.4 1 0 0 1 1 1 0 YjeF-related protein N-terminus 3HCDH_N PF02737.18 OAG41407.1 - 0.063 13.2 1.7 0.09 12.7 1.4 1.5 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Qn_am_d_aIII PF09099.10 OAG41407.1 - 0.065 13.6 1.0 0.22 11.9 0.5 2.2 2 0 0 2 2 2 0 Quinohemoprotein amine dehydrogenase, alpha subunit domain III Epimerase PF01370.21 OAG41407.1 - 0.13 11.7 0.5 1.5 8.2 0.5 2.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family YrhK PF14145.6 OAG41408.1 - 0.46 10.4 21.2 0.19 11.6 0.6 4.7 4 1 0 4 4 4 0 YrhK-like protein adh_short_C2 PF13561.6 OAG41409.1 - 1.2e-48 165.7 2.0 5.4e-40 137.4 0.9 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG41409.1 - 1.2e-45 155.4 1.2 1.5e-45 155.1 1.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG41409.1 - 4.9e-13 49.4 0.1 6.8e-13 48.9 0.1 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 OAG41409.1 - 0.0029 17.5 0.2 0.0049 16.8 0.2 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 OAG41409.1 - 0.0079 16.3 0.5 0.019 15.0 0.5 1.6 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain DDE_Tnp_1 PF01609.21 OAG41409.1 - 0.019 14.6 0.0 0.027 14.1 0.0 1.2 1 0 0 1 1 1 0 Transposase DDE domain 2-Hacid_dh_C PF02826.19 OAG41409.1 - 0.12 11.7 0.2 0.29 10.5 0.1 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.17 OAG41409.1 - 0.14 11.3 0.2 0.33 10.0 0.1 1.7 2 0 0 2 2 2 0 RmlD substrate binding domain MFS_1 PF07690.16 OAG41410.1 - 3e-36 125.1 54.3 3e-36 125.1 54.3 2.4 1 1 1 2 2 2 1 Major Facilitator Superfamily HATPase_c PF02518.26 OAG41412.1 - 1.2e-21 77.2 0.1 6.1e-21 75.0 0.1 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 OAG41412.1 - 1.4e-19 70.3 0.0 3.3e-19 69.1 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 OAG41412.1 - 3e-11 43.2 0.0 1.1e-10 41.4 0.0 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain GAF_3 PF13492.6 OAG41412.1 - 0.0032 17.8 0.0 1.3 9.4 0.0 4.0 3 1 0 3 3 3 1 GAF domain HATPase_c_5 PF14501.6 OAG41412.1 - 0.15 12.0 0.0 0.42 10.6 0.0 1.7 1 0 0 1 1 1 0 GHKL domain OPT PF03169.15 OAG41413.1 - 1.9e-145 485.9 17.7 1.9e-145 485.9 17.7 2.9 3 0 0 3 3 3 1 OPT oligopeptide transporter protein MFS_1 PF07690.16 OAG41413.1 - 5.7e-26 91.3 36.0 5.7e-26 91.3 36.0 6.1 2 2 3 5 5 5 2 Major Facilitator Superfamily TRI12 PF06609.13 OAG41414.1 - 7.4e-64 216.2 18.3 9.9e-64 215.8 18.3 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG41414.1 - 1.1e-21 77.2 48.1 7.2e-21 74.5 45.2 3.2 2 1 0 2 2 2 1 Major Facilitator Superfamily Fungal_trans_2 PF11951.8 OAG41415.1 - 0.0017 17.3 1.3 0.97 8.2 0.1 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain Cyclin_N PF00134.23 OAG41416.1 - 1.7e-15 56.9 0.5 3.2e-15 56.0 0.5 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 OAG41416.1 - 1.7e-06 28.1 0.0 0.00037 20.6 0.0 2.9 3 1 0 3 3 3 1 Cyclin, C-terminal domain TFIIB PF00382.19 OAG41416.1 - 0.0089 16.1 0.6 0.087 12.9 0.1 2.2 2 0 0 2 2 2 1 Transcription factor TFIIB repeat Cyclin_C_2 PF16899.5 OAG41416.1 - 0.029 14.7 0.1 0.1 13.0 0.0 1.8 2 0 0 2 2 2 0 Cyclin C-terminal domain RTA1 PF04479.13 OAG41418.1 - 1e-52 178.8 3.0 1e-52 178.8 3.0 1.5 2 0 0 2 2 2 1 RTA1 like protein DUF4191 PF13829.6 OAG41418.1 - 0.26 10.6 0.9 0.53 9.6 0.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) DUF1980 PF09323.10 OAG41418.1 - 0.28 11.1 2.3 0.52 10.2 2.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) PMT_4TMC PF16192.5 OAG41418.1 - 0.54 9.8 7.1 0.18 11.4 3.8 1.8 2 0 0 2 2 2 0 C-terminal four TMM region of protein-O-mannosyltransferase Fungal_trans_2 PF11951.8 OAG41419.1 - 3.9e-09 35.8 1.1 4.7e-09 35.5 0.5 1.4 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF3014 PF11219.8 OAG41419.1 - 0.13 12.5 0.0 9.3 6.5 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3014) Abhydrolase_3 PF07859.13 OAG41420.1 - 2.9e-39 135.1 0.0 1.1e-38 133.2 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 OAG41420.1 - 0.035 13.0 0.4 0.2 10.4 0.4 1.9 1 1 0 1 1 1 0 Steryl acetyl hydrolase MFS_1 PF07690.16 OAG41421.1 - 1.2e-17 63.9 25.0 3.1e-12 46.1 9.6 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 OAG41422.1 - 2.6e-38 131.8 31.5 2.6e-38 131.8 31.5 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Exo_endo_phos PF03372.23 OAG41423.1 - 3.9e-13 49.5 2.4 1.5e-12 47.5 0.3 2.6 2 1 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.7 OAG41423.1 - 1.5e-10 41.1 5.5 7.2e-07 29.4 0.5 2.7 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OAG41423.1 - 5.4e-09 35.7 4.5 1.2e-08 34.5 4.5 1.6 1 0 0 1 1 1 1 Leucine rich repeat LRR_1 PF00560.33 OAG41423.1 - 0.0022 18.3 4.9 3.3 8.6 1.0 4.8 4 1 0 4 4 4 1 Leucine Rich Repeat LRR_9 PF14580.6 OAG41423.1 - 0.013 15.0 0.2 0.024 14.2 0.2 1.3 1 0 0 1 1 1 0 Leucine-rich repeat LRR_6 PF13516.6 OAG41423.1 - 1.5 9.0 7.4 2.1 8.6 0.2 3.2 3 0 0 3 3 3 0 Leucine Rich repeat DUF5401 PF17380.2 OAG41424.1 - 0.068 11.2 8.5 0.079 11.0 8.5 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5401) RskA PF10099.9 OAG41424.1 - 0.3 11.3 3.8 0.31 11.3 3.2 1.3 1 1 0 1 1 1 0 Anti-sigma-K factor rskA DUF846 PF05832.12 OAG41425.1 - 3.5e-47 159.9 9.6 4.2e-47 159.7 9.6 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) TMEM220 PF15071.6 OAG41425.1 - 0.019 15.7 0.6 0.019 15.7 0.6 1.7 2 0 0 2 2 2 0 Transmembrane family 220, helix MpPF26 PF07666.11 OAG41425.1 - 0.057 13.5 6.5 0.34 11.0 0.1 2.1 2 0 0 2 2 2 0 M penetrans paralogue family 26 PAP2_3 PF14378.6 OAG41425.1 - 0.094 12.4 7.1 0.13 12.0 7.1 1.1 1 0 0 1 1 1 0 PAP2 superfamily DUF443 PF04276.12 OAG41425.1 - 2 8.1 9.0 0.33 10.7 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF443) TctB PF07331.11 OAG41425.1 - 4.8 7.5 13.6 9.3 6.5 4.8 2.3 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family Cation_efflux PF01545.21 OAG41426.1 - 5.4e-52 176.4 6.5 8.9e-52 175.7 6.5 1.4 1 0 0 1 1 1 1 Cation efflux family FGGY_C PF02782.16 OAG41426.1 - 1.4e-30 106.5 0.0 2.3e-30 105.8 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 OAG41426.1 - 8.7e-19 68.1 0.0 2.6e-12 46.9 0.0 2.2 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain ZT_dimer PF16916.5 OAG41426.1 - 5.9e-05 23.1 0.0 0.00017 21.7 0.0 1.7 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter tRNA-synt_1 PF00133.22 OAG41427.1 - 5.6e-214 711.8 0.6 6e-213 708.4 0.6 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 OAG41427.1 - 7.2e-35 120.2 3.3 1.1e-33 116.4 0.0 2.4 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 OAG41427.1 - 2.6e-11 42.9 4.6 9e-05 21.4 0.1 4.4 3 2 0 3 3 3 2 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 OAG41427.1 - 1.7e-06 27.7 0.1 1.7e-06 27.7 0.1 3.6 3 1 1 4 4 4 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 OAG41427.1 - 0.00097 18.6 0.0 0.023 14.0 0.0 2.6 2 1 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain PepSY PF03413.19 OAG41427.1 - 0.23 12.1 1.2 0.59 10.7 0.0 2.4 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain Methyltransf_2 PF00891.18 OAG41428.1 - 1e-20 74.0 0.0 1.4e-20 73.5 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 OAG41428.1 - 6.5e-05 22.8 0.1 0.00017 21.5 0.1 1.6 1 0 0 1 1 1 1 Dimerisation domain Dimerisation PF08100.11 OAG41428.1 - 0.0011 18.9 0.2 0.0026 17.8 0.2 1.7 1 0 0 1 1 1 1 Dimerisation domain Pkinase PF00069.25 OAG41429.1 - 3.7e-64 216.6 0.1 4.4e-64 216.4 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG41429.1 - 5.1e-18 65.3 0.0 9.4e-18 64.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OAG41429.1 - 9.7e-07 28.9 0.6 0.00012 22.1 0.1 2.6 2 1 1 3 3 3 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OAG41429.1 - 0.0038 16.1 0.0 0.0077 15.1 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase SUIM_assoc PF16619.5 OAG41429.1 - 0.013 15.6 0.9 0.016 15.2 0.9 1.3 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Kdo PF06293.14 OAG41429.1 - 0.027 13.8 0.2 0.053 12.9 0.2 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 OAG41429.1 - 0.069 12.7 0.8 0.14 11.8 0.1 1.9 2 0 0 2 2 2 0 Choline/ethanolamine kinase RNase_P_p30 PF01876.16 OAG41430.1 - 1.9e-59 200.7 0.0 3.4e-59 199.9 0.0 1.4 2 0 0 2 2 2 1 RNase P subunit p30 Ribosomal_S5_C PF03719.15 OAG41430.1 - 0.063 12.7 0.2 0.48 9.9 0.1 2.1 2 0 0 2 2 2 0 Ribosomal protein S5, C-terminal domain tRNA-synt_His PF13393.6 OAG41432.1 - 7.8e-41 140.3 0.0 1.4e-34 119.8 0.0 2.1 2 0 0 2 2 2 2 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 OAG41432.1 - 3.7e-11 43.0 0.1 9.2e-11 41.8 0.1 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2d PF01409.20 OAG41432.1 - 0.17 11.4 0.0 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class II core domain (F) CorA PF01544.18 OAG41433.1 - 0.0025 17.2 9.1 0.0025 17.2 9.1 1.8 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein Plasmo_rep PF12135.8 OAG41433.1 - 0.18 11.3 0.6 0.49 10.0 0.6 1.7 1 0 0 1 1 1 0 Plasmodium repeat family ADH_N PF08240.12 OAG41434.1 - 6.5e-07 29.2 0.1 2.4e-06 27.4 0.1 1.9 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG41434.1 - 0.091 12.7 0.1 0.26 11.3 0.1 1.8 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Fungal_trans_2 PF11951.8 OAG41435.1 - 0.0028 16.5 0.2 0.0046 15.8 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain ATP-synt_ab PF00006.25 OAG41436.1 - 7.4e-74 248.0 0.0 1.1e-73 247.4 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 OAG41436.1 - 3.2e-48 163.2 0.4 5.4e-48 162.5 0.4 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 OAG41436.1 - 7.2e-15 55.3 4.3 9.1e-15 54.9 2.9 2.0 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain DUF3659 PF12396.8 OAG41436.1 - 0.04 13.9 0.3 10 6.2 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3659) AAA_22 PF13401.6 OAG41436.1 - 0.11 12.8 0.0 0.41 10.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain DHHC PF01529.20 OAG41437.1 - 1.3e-35 122.5 10.1 1.3e-35 122.5 10.1 2.6 2 1 1 3 3 3 1 DHHC palmitoyltransferase Ank_2 PF12796.7 OAG41437.1 - 3.9e-32 110.7 0.3 1.7e-14 54.1 0.2 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OAG41437.1 - 1.6e-24 85.6 3.2 1.4e-08 34.8 0.0 4.9 2 1 4 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 OAG41437.1 - 3.9e-24 84.0 1.2 6.9e-07 29.4 0.0 6.0 6 0 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.6 OAG41437.1 - 2.1e-23 79.9 4.1 1.4e-07 31.2 0.0 6.2 5 0 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.6 OAG41437.1 - 1.1e-21 76.9 3.4 2.1e-06 28.2 0.0 4.7 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Cadherin_C_2 PF16492.5 OAG41437.1 - 0.055 14.2 0.1 1.8 9.4 0.0 2.7 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal p450 PF00067.22 OAG41438.1 - 2.1e-52 178.4 0.0 7.6e-52 176.6 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 Chal_sti_synt_N PF00195.19 OAG41439.1 - 1.1e-23 83.8 0.0 1.7e-23 83.3 0.0 1.2 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain Chal_sti_synt_C PF02797.15 OAG41439.1 - 1.8e-18 66.9 0.0 7.1e-18 65.0 0.0 1.9 2 0 0 2 2 2 1 Chalcone and stilbene synthases, C-terminal domain ACP_syn_III_C PF08541.10 OAG41439.1 - 2.7e-05 24.3 0.0 8.3e-05 22.7 0.0 1.8 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.10 OAG41439.1 - 0.0073 16.1 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III FAE1_CUT1_RppA PF08392.12 OAG41439.1 - 0.013 14.8 0.0 0.019 14.3 0.0 1.2 1 0 0 1 1 1 0 FAE1/Type III polyketide synthase-like protein Methyltransf_12 PF08242.12 OAG41440.1 - 0.039 14.7 0.0 0.061 14.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain TPP_enzyme_N PF02776.18 OAG41441.1 - 2.1e-41 141.4 0.2 4e-41 140.5 0.2 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 OAG41441.1 - 1.3e-34 118.9 0.0 2.8e-34 117.8 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 OAG41441.1 - 5.5e-19 68.4 0.0 6.5e-18 65.0 0.0 2.4 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain B12-binding PF02310.19 OAG41441.1 - 0.0034 17.4 0.1 0.011 15.7 0.1 1.9 1 0 0 1 1 1 1 B12 binding domain Methyltransf_23 PF13489.6 OAG41442.1 - 4e-18 65.8 0.0 5.2e-18 65.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG41442.1 - 4.9e-14 52.8 0.0 1.2e-13 51.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG41442.1 - 6.5e-14 52.5 0.0 1.7e-13 51.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG41442.1 - 1.8e-13 51.0 0.0 5.2e-13 49.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG41442.1 - 2.1e-12 47.1 0.0 1e-11 44.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAG41442.1 - 4.5e-05 22.9 0.0 0.00081 18.8 0.0 2.5 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family RrnaAD PF00398.20 OAG41442.1 - 9.7e-05 21.6 0.0 0.00012 21.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase NodS PF05401.11 OAG41442.1 - 0.00021 21.0 0.0 0.0013 18.4 0.0 1.9 2 0 0 2 2 2 1 Nodulation protein S (NodS) MTS PF05175.14 OAG41442.1 - 0.018 14.6 0.0 0.031 13.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_32 PF13679.6 OAG41442.1 - 0.051 13.6 0.0 0.078 13.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.9 OAG41442.1 - 0.063 13.0 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase PCMT PF01135.19 OAG41442.1 - 0.16 11.7 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DREV PF05219.12 OAG41442.1 - 0.19 10.8 0.0 0.35 9.9 0.0 1.4 1 0 0 1 1 1 0 DREV methyltransferase Peptidase_C50 PF03568.17 OAG41444.1 - 2.1e-140 468.3 0.0 4.4e-140 467.3 0.0 1.6 1 0 0 1 1 1 1 Peptidase family C50 TPR_12 PF13424.6 OAG41444.1 - 1.2e-10 41.5 0.8 2.1e-07 31.1 0.1 3.8 2 0 0 2 2 2 2 Tetratricopeptide repeat CHAT PF12770.7 OAG41444.1 - 1.8e-05 24.3 0.0 0.015 14.7 0.0 2.9 1 1 0 2 2 2 2 CHAT domain TPR_2 PF07719.17 OAG41444.1 - 0.00074 19.5 4.1 2.1 8.7 0.2 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 OAG41444.1 - 0.02 15.4 2.8 0.82 10.2 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 OAG41444.1 - 0.06 13.2 4.9 1.5 8.8 0.1 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 OAG41444.1 - 0.36 11.6 3.2 41 5.1 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 OAG41444.1 - 0.47 10.8 4.4 42 4.7 0.1 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 OAG41444.1 - 1.1 9.5 5.1 32 4.9 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 OAG41444.1 - 8 7.6 11.1 36 5.6 0.1 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat SUZ PF12752.7 OAG41445.1 - 0.019 15.7 6.1 0.06 14.1 6.1 1.8 1 0 0 1 1 1 0 SUZ domain DUF5321 PF17254.2 OAG41446.1 - 5.7e-60 201.4 7.2 7e-60 201.1 7.2 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5321) Nicastrin PF05450.15 OAG41446.1 - 0.16 11.4 0.1 0.25 10.8 0.1 1.3 1 0 0 1 1 1 0 Nicastrin Olfactory_mark PF06554.12 OAG41447.1 - 0.043 13.6 0.0 0.055 13.2 0.0 1.1 1 0 0 1 1 1 0 Olfactory marker protein NTF2 PF02136.20 OAG41448.1 - 2.8e-26 92.5 0.2 4.5e-26 91.8 0.2 1.4 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.22 OAG41448.1 - 2.4e-06 27.3 0.0 4.6e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OAG41448.1 - 0.093 12.6 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Occluded RNA-recognition motif Lipase3_N PF03893.16 OAG41448.1 - 2 8.5 5.5 3.3 7.8 0.1 2.5 2 0 0 2 2 2 0 Lipase 3 N-terminal region Septin PF00735.18 OAG41449.1 - 1.8e-12 47.2 0.0 7.2e-08 32.1 0.0 2.2 2 0 0 2 2 2 2 Septin AAA_16 PF13191.6 OAG41449.1 - 0.00062 20.2 0.0 0.0016 18.8 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 OAG41449.1 - 0.004 17.2 0.0 0.0085 16.2 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase NTPase_1 PF03266.15 OAG41449.1 - 0.016 15.1 0.1 0.03 14.3 0.1 1.4 1 0 0 1 1 1 0 NTPase AAA_7 PF12775.7 OAG41449.1 - 0.017 14.6 0.1 0.074 12.6 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region ATPase_2 PF01637.18 OAG41449.1 - 0.02 14.8 0.0 0.043 13.7 0.0 1.5 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA PF00004.29 OAG41449.1 - 0.026 15.0 0.0 0.057 13.8 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Roc PF08477.13 OAG41449.1 - 0.069 13.4 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase APH PF01636.23 OAG41451.1 - 6e-17 62.4 0.0 2.8e-16 60.2 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 OAG41451.1 - 2.5e-05 24.0 0.0 0.16 11.5 0.0 2.1 2 0 0 2 2 2 2 RIO1 family Pkinase PF00069.25 OAG41451.1 - 0.013 14.9 0.0 0.59 9.5 0.0 2.1 2 0 0 2 2 2 0 Protein kinase domain Choline_kinase PF01633.20 OAG41451.1 - 0.014 15.0 0.0 0.02 14.5 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase_Tyr PF07714.17 OAG41451.1 - 0.12 11.6 0.0 0.2 10.9 0.0 1.3 1 1 0 1 1 1 0 Protein tyrosine kinase Kdo PF06293.14 OAG41451.1 - 0.14 11.5 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DLH PF01738.18 OAG41452.1 - 2e-26 92.9 0.0 3.2e-26 92.3 0.0 1.3 1 1 0 1 1 1 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 OAG41452.1 - 0.014 14.7 0.2 0.82 8.9 0.0 2.7 3 0 0 3 3 3 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OAG41452.1 - 0.075 12.7 0.2 5.1 6.7 0.0 2.8 2 1 1 3 3 3 0 alpha/beta hydrolase fold MFS_1 PF07690.16 OAG41453.1 - 2.8e-49 167.9 34.5 2.8e-49 167.9 34.5 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.18 OAG41453.1 - 6e-24 84.5 0.0 1.1e-23 83.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sugar_tr PF00083.24 OAG41453.1 - 1.1e-17 64.0 2.8 1.1e-17 64.0 2.8 1.9 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 OAG41453.1 - 1.1e-05 25.0 2.6 1.1e-05 25.0 2.6 2.1 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB TRI12 PF06609.13 OAG41453.1 - 0.00069 18.2 5.6 0.00078 18.0 4.3 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Fungal_trans_2 PF11951.8 OAG41453.1 - 0.0017 17.2 0.6 0.0091 14.9 0.0 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain OATP PF03137.20 OAG41453.1 - 0.017 13.4 0.2 0.017 13.4 0.2 2.5 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.24 OAG41455.1 - 2.5e-79 267.3 21.9 3.1e-79 266.9 21.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG41455.1 - 2.8e-21 75.8 27.1 2.8e-21 75.8 27.1 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily GFA PF04828.14 OAG41456.1 - 8.1e-17 61.4 0.2 1e-16 61.0 0.2 1.1 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme WSC PF01822.19 OAG41458.1 - 2.8e-32 110.7 26.7 1.9e-17 63.2 12.8 2.1 2 0 0 2 2 2 2 WSC domain WSC PF01822.19 OAG41460.1 - 1.1e-47 160.2 60.2 3.4e-16 59.2 11.9 4.4 4 0 0 4 4 4 4 WSC domain ASH PF15780.5 OAG41460.1 - 1.9e-05 24.8 7.0 0.076 13.2 0.0 3.5 3 0 0 3 3 3 3 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin DUF1573 PF07610.11 OAG41460.1 - 0.002 18.1 1.5 9.1 6.4 0.0 4.2 3 1 0 3 3 3 1 Protein of unknown function (DUF1573) PQQ_3 PF13570.6 OAG41460.1 - 0.021 15.3 12.8 0.31 11.6 0.8 5.2 4 0 0 4 4 4 0 PQQ-like domain p450 PF00067.22 OAG41462.1 - 1.8e-46 158.9 0.0 2.5e-46 158.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_S49_N PF08496.10 OAG41463.1 - 0.88 9.6 6.1 1.3 9.1 6.1 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Abhydrolase_3 PF07859.13 OAG41464.1 - 1.8e-13 50.9 0.1 3e-13 50.1 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OAG41464.1 - 4.2e-08 32.9 0.0 0.00052 19.6 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family COesterase PF00135.28 OAG41464.1 - 0.0006 18.8 0.0 0.0009 18.2 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Chlorophyllase2 PF12740.7 OAG41464.1 - 0.00076 18.5 0.0 0.0011 18.0 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 OAG41464.1 - 0.017 14.4 0.0 0.095 12.0 0.0 2.0 1 1 0 1 1 1 0 Serine aminopeptidase, S33 AXE1 PF05448.12 OAG41464.1 - 0.21 10.2 0.5 4.2 5.9 0.1 2.1 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Glyco_transf_34 PF05637.12 OAG41465.1 - 6.4e-64 215.9 0.0 8.7e-64 215.5 0.0 1.2 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Fungus-induced PF10917.8 OAG41465.1 - 4.3e-05 23.7 0.1 7.7e-05 22.9 0.1 1.4 1 0 0 1 1 1 1 Fungus-induced protein Pkinase PF00069.25 OAG41466.1 - 1.2e-64 218.3 0.0 5.5e-64 216.1 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG41466.1 - 1.1e-32 113.3 0.0 2.6e-32 112.2 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 OAG41466.1 - 3.6e-09 36.8 0.1 1.6e-08 34.7 0.1 2.1 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 OAG41466.1 - 0.00014 22.1 0.0 0.00041 20.6 0.0 1.7 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Kinase-like PF14531.6 OAG41466.1 - 0.014 14.8 0.0 0.13 11.5 0.0 2.0 1 1 0 1 1 1 0 Kinase-like Kdo PF06293.14 OAG41466.1 - 0.036 13.4 0.1 0.063 12.6 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 OAG41466.1 - 0.049 12.6 0.1 0.078 11.9 0.1 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase FlaC_arch PF05377.11 OAG41467.1 - 0.089 13.2 1.8 0.24 11.8 0.4 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Beta_elim_lyase PF01212.21 OAG41468.1 - 1.2e-71 241.4 0.0 1.5e-71 241.0 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 OAG41468.1 - 7.7e-06 25.3 0.0 1e-05 24.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 OAG41468.1 - 0.0011 17.6 0.0 0.002 16.7 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 OAG41468.1 - 0.0057 16.0 0.0 0.015 14.6 0.0 1.7 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family RhoGAP PF00620.27 OAG41469.1 - 3.4e-38 130.9 0.1 5.6e-38 130.1 0.1 1.3 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.22 OAG41470.1 - 1.4e-34 118.1 31.1 2.8e-12 46.7 4.5 5.1 5 0 0 5 5 5 4 LIM domain DZR PF12773.7 OAG41470.1 - 0.25 11.4 22.1 0.53 10.4 1.0 4.4 3 1 0 3 3 3 0 Double zinc ribbon Desulfoferrod_N PF06397.12 OAG41470.1 - 0.27 10.9 0.1 0.27 10.9 0.1 2.8 3 0 0 3 3 3 0 Desulfoferrodoxin, N-terminal domain HSP20 PF00011.21 OAG41471.1 - 3.8e-08 33.4 0.0 5.2e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family HSP20 PF00011.21 OAG41472.1 - 4.1e-09 36.5 0.0 2e-08 34.3 0.0 1.9 1 1 0 1 1 1 1 Hsp20/alpha crystallin family IBR PF01485.21 OAG41473.1 - 1e-14 54.5 39.5 6.6e-08 32.7 7.1 3.4 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain zf-RING_7 PF02591.15 OAG41473.1 - 0.01 16.0 3.3 1.5 9.0 0.0 3.6 3 0 0 3 3 3 2 C4-type zinc ribbon domain Thiolase_N PF00108.23 OAG41474.1 - 7.2e-94 314.0 0.5 1.3e-93 313.2 0.1 1.6 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 OAG41474.1 - 5.3e-44 148.8 1.7 1.3e-43 147.6 1.7 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 OAG41474.1 - 2.6e-05 23.9 0.4 5.5e-05 22.9 0.4 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 OAG41474.1 - 0.0024 17.7 2.7 0.054 13.4 0.1 2.9 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Pkinase PF00069.25 OAG41475.1 - 2.1e-59 201.0 0.0 6e-59 199.6 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG41475.1 - 6.5e-36 123.9 0.0 1.2e-35 123.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.16 OAG41475.1 - 3.5e-26 91.1 24.8 2.5e-14 53.1 4.1 2.9 3 0 0 3 3 3 2 Hr1 repeat C1_1 PF00130.22 OAG41475.1 - 6.1e-20 70.8 28.6 6e-12 45.3 9.9 2.4 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.24 OAG41475.1 - 8.7e-09 35.9 1.1 3.3e-08 34.1 1.1 2.1 1 0 0 1 1 1 1 Protein kinase C terminal domain C2 PF00168.30 OAG41475.1 - 2.5e-05 24.5 0.1 4.8e-05 23.6 0.1 1.5 1 0 0 1 1 1 1 C2 domain Kinase-like PF14531.6 OAG41475.1 - 0.045 13.1 0.0 0.087 12.1 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Clathrin PF00637.20 OAG41476.1 - 8.8e-22 77.5 1.9 5.1e-20 71.8 0.5 2.7 2 0 0 2 2 2 1 Region in Clathrin and VPS VPS11_C PF12451.8 OAG41476.1 - 5e-19 68.3 0.4 9.9e-19 67.3 0.4 1.5 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal zf-C3H2C3 PF17122.5 OAG41476.1 - 0.0002 21.3 6.7 0.00077 19.5 6.7 2.0 1 1 0 1 1 1 1 Zinc-finger zf-RING_2 PF13639.6 OAG41476.1 - 0.00045 20.5 6.1 0.00092 19.5 6.1 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 OAG41476.1 - 0.00052 19.8 6.6 0.0012 18.7 6.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAG41476.1 - 0.00072 19.5 5.8 0.0014 18.5 5.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain TPR_11 PF13414.6 OAG41476.1 - 0.00082 19.0 0.3 0.0022 17.6 0.3 1.7 1 0 0 1 1 1 1 TPR repeat zf-RING_UBOX PF13445.6 OAG41476.1 - 0.0021 18.1 4.2 0.0046 17.0 4.2 1.6 1 0 0 1 1 1 1 RING-type zinc-finger TPR_14 PF13428.6 OAG41476.1 - 0.0034 18.1 0.8 0.34 11.8 0.0 4.3 5 0 0 5 5 2 1 Tetratricopeptide repeat zf-HC5HC2H PF13771.6 OAG41476.1 - 0.006 16.8 0.9 0.014 15.7 0.9 1.6 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-rbx1 PF12678.7 OAG41476.1 - 0.0076 16.5 4.4 0.017 15.4 4.4 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 OAG41476.1 - 0.0085 15.9 7.0 0.018 14.9 7.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 OAG41476.1 - 0.01 15.9 1.5 0.022 14.8 1.5 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger eIF3_N PF09440.10 OAG41476.1 - 0.017 15.5 0.5 0.054 13.9 0.5 1.8 1 0 0 1 1 1 0 eIF3 subunit 6 N terminal domain TPR_12 PF13424.6 OAG41476.1 - 0.035 14.4 4.3 0.12 12.7 0.4 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 OAG41476.1 - 0.044 13.9 1.8 0.2 11.8 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-HC5HC2H_2 PF13832.6 OAG41476.1 - 0.094 12.9 0.8 0.22 11.7 0.8 1.6 1 0 0 1 1 1 0 PHD-zinc-finger like domain DUF4810 PF16068.5 OAG41476.1 - 0.13 12.8 0.1 21 5.8 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4810) PHD PF00628.29 OAG41476.1 - 0.46 10.4 4.3 0.98 9.4 4.3 1.6 1 0 0 1 1 1 0 PHD-finger zf-RING_11 PF17123.5 OAG41476.1 - 1.6 8.6 4.8 4.1 7.2 4.8 1.8 1 0 0 1 1 1 0 RING-like zinc finger zf-C3HC4_4 PF15227.6 OAG41476.1 - 2.7 8.2 5.4 5.5 7.2 5.4 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING TPR_8 PF13181.6 OAG41476.1 - 4.3 7.8 5.0 1.7 9.1 0.3 2.8 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 OAG41476.1 - 5.3 7.0 5.7 3.3 7.7 0.3 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Asp PF00026.23 OAG41477.1 - 9.4e-12 45.0 0.0 1.6e-11 44.2 0.0 1.3 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OAG41477.1 - 0.066 13.5 0.2 0.39 10.9 0.0 2.4 2 0 0 2 2 2 0 Xylanase inhibitor N-terminal SKG6 PF08693.10 OAG41477.1 - 0.18 11.2 0.1 0.33 10.4 0.1 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF92 PF01940.16 OAG41479.1 - 1.8e-78 263.2 9.5 2.1e-78 263.0 9.5 1.0 1 0 0 1 1 1 1 Integral membrane protein DUF92 Radical_SAM PF04055.21 OAG41480.1 - 4e-10 40.3 0.0 6.6e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 OAG41480.1 - 3.8e-05 24.0 0.0 6.2e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 OAG41480.1 - 0.024 14.8 0.2 0.045 13.9 0.2 1.5 1 1 0 1 1 1 0 4Fe-4S single cluster domain SAM_Exu PF18609.1 OAG41481.1 - 0.14 12.3 0.6 0.29 11.3 0.6 1.5 1 0 0 1 1 1 0 Exuperantia SAM-like domain BRE1 PF08647.11 OAG41481.1 - 1.1 9.3 4.1 3.2 7.9 2.8 2.0 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase GMC_oxred_N PF00732.19 OAG41482.1 - 4.4e-65 220.0 0.0 5.6e-65 219.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAG41482.1 - 1.1e-30 107.1 0.0 2.1e-30 106.2 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 OAG41482.1 - 4e-05 22.9 0.2 6e-05 22.3 0.2 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 OAG41482.1 - 0.00053 20.2 0.1 0.002 18.3 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAG41482.1 - 0.00071 19.3 0.8 0.0073 15.9 0.2 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OAG41482.1 - 0.0039 16.3 1.8 0.045 12.8 0.5 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 OAG41482.1 - 0.021 14.0 0.2 0.043 13.1 0.0 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAG41482.1 - 0.028 13.7 0.1 0.06 12.6 0.1 1.5 1 0 0 1 1 1 0 Thi4 family GST_C_3 PF14497.6 OAG41483.1 - 3.6e-18 65.6 0.0 5.4e-18 65.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 OAG41483.1 - 6.9e-05 23.1 0.0 0.00017 21.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 OAG41483.1 - 0.00035 20.9 0.0 0.00089 19.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OAG41483.1 - 0.00087 19.5 0.1 0.021 15.1 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OAG41483.1 - 0.063 13.3 0.1 0.11 12.5 0.1 1.6 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Methyltransf_25 PF13649.6 OAG41484.1 - 5.3e-16 59.1 0.1 2.3e-15 57.1 0.1 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG41484.1 - 3.6e-13 50.0 0.0 1.3e-11 45.0 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAG41484.1 - 8.5e-13 48.5 0.0 1.2e-12 48.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG41484.1 - 8.2e-11 42.5 0.0 1.5e-10 41.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG41484.1 - 9.5e-11 41.7 0.0 1.4e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAG41484.1 - 7.1e-05 22.2 0.0 0.00016 21.1 0.0 1.6 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 OAG41484.1 - 0.0012 18.5 0.0 0.18 11.3 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase small domain NodS PF05401.11 OAG41484.1 - 0.0033 17.0 0.0 0.2 11.2 0.0 2.1 2 0 0 2 2 2 1 Nodulation protein S (NodS) Pox_MCEL PF03291.16 OAG41484.1 - 0.0049 16.0 0.0 0.0073 15.5 0.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_32 PF13679.6 OAG41484.1 - 0.03 14.3 0.0 0.042 13.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_9 PF08003.11 OAG41484.1 - 0.045 12.7 0.0 0.067 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) PCMT PF01135.19 OAG41484.1 - 0.055 13.2 0.0 0.093 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.19 OAG41484.1 - 0.084 13.0 0.0 0.14 12.2 0.0 1.5 1 1 0 1 1 1 0 FtsJ-like methyltransferase Bmt2 PF11968.8 OAG41484.1 - 0.19 11.5 0.0 0.31 10.9 0.0 1.2 1 0 0 1 1 1 0 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 IRF-2BP1_2 PF11261.8 OAG41486.1 - 0.053 13.1 0.1 0.12 11.9 0.1 1.5 1 0 0 1 1 1 0 Interferon regulatory factor 2-binding protein zinc finger Ubie_methyltran PF01209.18 OAG41487.1 - 2.2e-11 43.6 0.1 1e-09 38.1 0.0 2.1 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 OAG41487.1 - 9.6e-10 39.0 0.0 2e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG41487.1 - 3.5e-09 37.2 0.0 1e-08 35.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAG41487.1 - 2.7e-08 33.8 0.0 5.1e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG41487.1 - 1.3e-06 29.1 0.0 2.9e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG41487.1 - 0.0015 18.3 0.0 0.48 10.2 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain ERCC4 PF02732.15 OAG41488.1 - 4.7e-17 62.6 0.0 1.6e-16 60.9 0.0 1.8 1 1 0 2 2 2 1 ERCC4 domain LSM PF01423.22 OAG41488.1 - 0.11 12.2 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 LSM domain DUF3987 PF13148.6 OAG41488.1 - 7.6 5.4 9.7 14 4.6 9.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Glycos_transf_1 PF00534.20 OAG41489.1 - 3e-31 108.3 0.0 8.7e-22 77.5 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 OAG41489.1 - 1.5e-16 60.9 0.0 3.4e-16 59.7 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 OAG41489.1 - 5.7e-13 49.5 0.0 2.8e-12 47.2 0.0 2.1 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 OAG41489.1 - 1.2e-06 29.0 2.4 3.3e-06 27.6 0.1 2.4 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 OAG41489.1 - 1.4e-05 25.4 0.0 3e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 ALG11_N PF15924.5 OAG41489.1 - 0.0017 18.4 0.0 0.28 11.2 0.0 2.7 1 1 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glyco_trans_4_5 PF16994.5 OAG41489.1 - 0.052 13.2 0.0 0.099 12.2 0.0 1.4 1 0 0 1 1 1 0 Glycosyl-transferase family 4 Glyco_hydro_72 PF03198.14 OAG41490.1 - 2.4e-122 408.1 0.0 2.9e-122 407.8 0.0 1.0 1 0 0 1 1 1 1 Glucanosyltransferase MARVEL PF01284.23 OAG41491.1 - 0.00018 21.6 12.8 0.00024 21.2 12.8 1.2 1 0 0 1 1 1 1 Membrane-associating domain Flavokinase PF01687.17 OAG41492.1 - 5.6e-10 39.5 0.0 1e-09 38.7 0.0 1.4 1 0 0 1 1 1 1 Riboflavin kinase FAD_binding_3 PF01494.19 OAG41493.1 - 1.8e-18 66.9 0.1 1.8e-18 66.9 0.1 2.2 2 1 0 2 2 2 1 FAD binding domain DAO PF01266.24 OAG41493.1 - 7.7e-07 29.0 0.0 0.00099 18.8 0.0 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG41493.1 - 5.5e-05 22.5 0.1 0.013 14.7 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 OAG41493.1 - 0.00051 19.0 0.8 1.2 7.9 0.0 3.0 3 0 0 3 3 3 2 Tryptophan halogenase Pyr_redox PF00070.27 OAG41493.1 - 0.00053 20.5 0.4 0.19 12.3 0.1 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAG41493.1 - 0.0011 17.7 0.1 0.033 12.9 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein Lycopene_cycl PF05834.12 OAG41493.1 - 0.0012 17.9 2.0 0.0056 15.8 0.0 2.3 3 0 0 3 3 3 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 OAG41493.1 - 0.0074 16.3 0.8 0.07 13.1 0.1 2.6 2 1 0 2 2 2 1 FAD-NAD(P)-binding SE PF08491.10 OAG41493.1 - 0.02 13.9 0.0 0.034 13.2 0.0 1.3 1 0 0 1 1 1 0 Squalene epoxidase NAD_binding_8 PF13450.6 OAG41493.1 - 0.039 14.2 0.0 0.1 12.8 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain ADH_N PF08240.12 OAG41494.1 - 1.2e-30 105.6 3.3 2.6e-30 104.5 3.3 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG41494.1 - 1.9e-25 89.4 3.9 2.5e-25 88.9 3.2 1.6 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAG41494.1 - 1.2e-06 29.7 0.4 1.9e-06 29.0 0.4 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 OAG41494.1 - 2.6e-05 23.8 1.4 3.7e-05 23.3 1.4 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus Shikimate_DH PF01488.20 OAG41494.1 - 0.006 16.7 0.0 0.011 15.8 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase adh_short PF00106.25 OAG41494.1 - 0.006 16.1 0.1 0.013 15.0 0.1 1.6 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_7 PF13241.6 OAG41494.1 - 0.0065 16.9 1.0 0.016 15.7 0.4 1.9 2 0 0 2 2 2 1 Putative NAD(P)-binding Pyr_redox PF00070.27 OAG41494.1 - 0.047 14.2 0.6 0.18 12.4 0.4 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 OAG41494.1 - 0.079 12.2 0.3 0.13 11.5 0.3 1.2 1 0 0 1 1 1 0 FAD binding domain F420_oxidored PF03807.17 OAG41494.1 - 0.11 13.1 0.5 0.27 11.9 0.2 1.9 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.18 OAG41494.1 - 0.13 12.5 0.8 0.22 11.8 0.2 1.6 2 0 0 2 2 2 0 TrkA-N domain MFS_1 PF07690.16 OAG41495.1 - 6.7e-41 140.4 55.4 6.7e-41 140.4 55.4 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG41495.1 - 1.3e-11 44.1 17.1 1.3e-11 44.1 17.1 3.1 2 1 1 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 OAG41495.1 - 2.1e-11 43.0 29.7 1.2e-10 40.5 29.7 2.0 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) PGA2 PF07543.12 OAG41496.1 - 1.4e-06 28.4 0.0 1.8e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Protein trafficking PGA2 Amidase_2 PF01510.25 OAG41496.1 - 0.069 13.6 0.0 0.11 13.0 0.0 1.4 1 0 0 1 1 1 0 N-acetylmuramoyl-L-alanine amidase AtuA PF07287.11 OAG41497.1 - 3.9e-124 413.9 0.0 4.6e-124 413.7 0.0 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA RRM_1 PF00076.22 OAG41498.1 - 7.9e-46 153.8 0.0 7.4e-17 60.9 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 OAG41498.1 - 2e-06 27.7 0.0 0.0015 18.5 0.0 3.1 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 OAG41498.1 - 2.4e-05 24.1 0.0 0.056 13.3 0.0 2.5 2 0 0 2 2 2 2 Occluded RNA-recognition motif RRM_3 PF08777.11 OAG41498.1 - 0.0003 20.8 0.0 0.0012 18.9 0.0 1.9 2 0 0 2 2 2 1 RNA binding motif RRM_7 PF16367.5 OAG41498.1 - 0.0015 18.6 0.4 0.05 13.7 0.0 3.1 3 1 0 3 3 3 1 RNA recognition motif PHM7_cyt PF14703.6 OAG41498.1 - 0.016 15.5 0.0 2 8.6 0.0 3.4 3 1 1 4 4 4 0 Cytosolic domain of 10TM putative phosphate transporter RRM_5 PF13893.6 OAG41498.1 - 0.02 14.5 0.0 0.054 13.1 0.0 1.7 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Acetyltransf_1 PF00583.25 OAG41499.1 - 4.6e-05 23.6 0.0 9.4e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OAG41499.1 - 0.00024 21.5 0.0 0.00049 20.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OAG41499.1 - 0.079 12.9 0.0 0.22 11.5 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 OAG41499.1 - 0.2 11.7 0.0 0.55 10.2 0.0 1.7 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Arf PF00025.21 OAG41500.1 - 1.8e-63 213.2 1.3 2e-63 213.0 1.3 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 OAG41500.1 - 1.3e-12 48.0 0.1 1.7e-12 47.6 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 OAG41500.1 - 1.8e-12 47.1 3.0 3.4e-07 29.7 0.7 2.7 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 OAG41500.1 - 1e-11 44.7 0.1 1.3e-11 44.3 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.22 OAG41500.1 - 6.5e-10 38.8 0.0 7.8e-10 38.6 0.0 1.1 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 OAG41500.1 - 4.5e-08 33.2 0.0 7.3e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 OAG41500.1 - 6.4e-07 29.0 0.0 8.3e-07 28.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 OAG41500.1 - 6.6e-05 22.5 0.0 0.002 17.7 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 OAG41500.1 - 0.0096 15.5 0.2 0.027 14.0 0.2 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B cobW PF02492.19 OAG41500.1 - 0.01 15.4 0.1 0.33 10.5 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain 6PF2K PF01591.18 OAG41500.1 - 0.11 11.8 0.1 0.23 10.8 0.1 1.4 1 1 0 1 1 1 0 6-phosphofructo-2-kinase DUF4045 PF13254.6 OAG41501.1 - 4.9e-106 355.9 40.3 4.9e-106 355.9 40.3 5.9 3 2 2 5 5 5 1 Domain of unknown function (DUF4045) Gelsolin PF00626.22 OAG41501.1 - 2.1e-11 43.6 0.0 0.0012 18.7 0.0 4.0 3 0 0 3 3 3 3 Gelsolin repeat ALO PF04030.14 OAG41502.1 - 7.5e-87 291.4 0.0 9.8e-87 291.1 0.0 1.1 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 OAG41502.1 - 3.7e-26 91.5 0.0 5.7e-26 90.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Sugar_tr PF00083.24 OAG41504.1 - 7.5e-92 308.5 20.5 9.5e-92 308.2 20.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG41504.1 - 4.2e-13 48.9 51.0 1.4e-08 34.1 16.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MARVEL PF01284.23 OAG41505.1 - 4.1e-18 65.8 9.1 5e-18 65.5 9.1 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF2976 PF11190.8 OAG41505.1 - 0.028 14.2 1.2 0.047 13.5 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) DUF588 PF04535.12 OAG41505.1 - 0.58 9.9 4.8 9.1 6.1 4.8 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF588) Fungal_trans_2 PF11951.8 OAG41507.1 - 6.9e-14 51.4 0.0 3.9e-13 49.0 0.0 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain COesterase PF00135.28 OAG41508.1 - 5.6e-72 243.3 0.0 7.2e-72 242.9 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAG41508.1 - 0.00089 19.2 0.0 0.00089 19.2 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OAG41508.1 - 0.016 14.7 0.0 0.027 13.9 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF4336 PF14234.6 OAG41509.1 - 1.3e-15 57.5 0.6 2e-12 47.0 0.3 2.6 2 1 0 2 2 2 2 Domain of unknown function (DUF4336) Patatin PF01734.22 OAG41511.1 - 2.3e-27 96.5 0.2 6.2e-27 95.1 0.2 1.8 1 0 0 1 1 1 1 Patatin-like phospholipase zf-RING_5 PF14634.6 OAG41511.1 - 0.0023 17.9 6.4 0.0023 17.9 6.4 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 OAG41511.1 - 0.018 14.9 6.5 0.054 13.4 6.5 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OAG41511.1 - 0.095 12.9 7.7 0.69 10.1 7.7 2.4 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 OAG41511.1 - 0.42 11.0 7.3 1.3 9.5 7.3 1.9 1 0 0 1 1 1 0 Ring finger domain FYVE_2 PF02318.16 OAG41511.1 - 0.45 10.7 6.3 0.13 12.5 0.9 2.7 2 0 0 2 2 2 0 FYVE-type zinc finger PRP38 PF03371.15 OAG41512.1 - 4.5e-62 209.0 0.0 5.9e-62 208.6 0.0 1.1 1 0 0 1 1 1 1 PRP38 family PRP38_assoc PF12871.7 OAG41512.1 - 0.00018 22.1 15.8 0.00018 22.1 15.8 1.6 2 0 0 2 2 2 1 Pre-mRNA-splicing factor 38-associated hydrophilic C-term RP-C_C PF11800.8 OAG41512.1 - 0.045 13.8 1.5 0.084 13.0 1.5 1.4 1 0 0 1 1 1 0 Replication protein C C-terminal region DUF4407 PF14362.6 OAG41512.1 - 0.067 12.5 0.1 0.087 12.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RRN3 PF05327.11 OAG41512.1 - 0.14 10.7 0.5 0.17 10.4 0.5 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Paf1 PF03985.13 OAG41512.1 - 0.17 10.8 5.1 0.22 10.5 5.1 1.1 1 0 0 1 1 1 0 Paf1 CDC45 PF02724.14 OAG41512.1 - 0.74 8.0 4.7 0.91 7.7 4.7 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF3445 PF11927.8 OAG41514.1 - 7.8e-77 257.9 0.0 1e-76 257.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Bac_rhamnosid_N PF08531.10 OAG41514.1 - 0.17 11.7 0.1 0.33 10.8 0.1 1.4 1 0 0 1 1 1 0 Alpha-L-rhamnosidase N-terminal domain MMR_HSR1 PF01926.23 OAG41515.1 - 2.1e-14 53.6 0.0 3.9e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OAG41515.1 - 1.9e-05 24.2 0.0 2.9e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 OAG41515.1 - 6.7e-05 22.8 0.0 0.00018 21.5 0.0 1.6 1 1 0 1 1 1 1 RsgA GTPase AIG1 PF04548.16 OAG41515.1 - 0.00043 19.7 0.0 0.0007 19.0 0.0 1.3 1 0 0 1 1 1 1 AIG1 family Septin PF00735.18 OAG41515.1 - 0.001 18.4 0.0 0.0016 17.8 0.0 1.2 1 0 0 1 1 1 1 Septin Dynamin_N PF00350.23 OAG41515.1 - 0.02 15.0 0.3 0.15 12.1 0.1 2.2 1 1 1 2 2 2 0 Dynamin family Roc PF08477.13 OAG41515.1 - 0.029 14.6 0.1 0.085 13.1 0.0 1.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase IIGP PF05049.13 OAG41515.1 - 0.054 12.5 0.0 0.098 11.7 0.0 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_16 PF13191.6 OAG41515.1 - 0.088 13.2 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain WD40 PF00400.32 OAG41516.1 - 2.3e-14 53.6 24.8 0.31 12.0 0.1 9.1 8 1 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG41516.1 - 0.053 13.8 1.7 21 5.5 0.0 4.2 5 0 0 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain Rhomboid PF01694.22 OAG41517.1 - 1.9e-22 79.9 10.3 1.9e-22 79.9 10.3 1.9 1 1 1 2 2 2 1 Rhomboid family HSCB_C PF07743.13 OAG41517.1 - 0.013 16.0 4.9 0.013 16.0 4.9 1.8 2 0 0 2 2 2 0 HSCB C-terminal oligomerisation domain Lactamase_B PF00753.27 OAG41518.1 - 5.9e-19 68.8 4.0 7.3e-19 68.6 4.0 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OAG41518.1 - 6.3e-05 22.6 0.3 0.00012 21.7 0.3 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain PGM_PMM_I PF02878.16 OAG41518.1 - 0.19 11.4 0.0 0.4 10.4 0.0 1.5 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I LmjF365940-deam PF14421.6 OAG41518.1 - 0.19 11.3 0.0 0.4 10.3 0.0 1.5 2 0 0 2 2 2 0 A distinct subfamily of CDD/CDA-like deaminases Lipase_3 PF01764.25 OAG41519.1 - 3.3e-33 114.5 0.0 4.9e-33 114.0 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Lipase3_N PF03893.16 OAG41519.1 - 4.2e-10 39.5 0.0 8.6e-10 38.5 0.0 1.5 1 0 0 1 1 1 1 Lipase 3 N-terminal region Hydrolase_4 PF12146.8 OAG41519.1 - 0.0016 17.7 0.0 0.0027 17.0 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_8 PF06259.12 OAG41519.1 - 0.0017 18.0 0.0 0.0033 17.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase Abhydrolase_6 PF12697.7 OAG41519.1 - 0.0095 16.6 0.0 0.014 16.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.8 OAG41519.1 - 0.044 13.3 0.3 0.19 11.3 0.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2974) Esterase PF00756.20 OAG41519.1 - 0.13 11.9 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 Putative esterase DUF676 PF05057.14 OAG41519.1 - 0.2 11.1 0.0 0.42 10.1 0.0 1.5 2 0 0 2 2 2 0 Putative serine esterase (DUF676) CAF1C_H4-bd PF12265.8 OAG41522.1 - 8.6e-14 51.6 0.1 5e-13 49.1 0.0 2.3 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 OAG41522.1 - 2.4e-12 47.1 9.5 8.9e-07 29.5 0.1 4.3 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG41522.1 - 8.3e-09 35.6 0.9 0.00052 20.3 0.1 3.4 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain UL41A PF17591.2 OAG41522.1 - 0.031 14.3 0.0 0.093 12.8 0.0 1.8 1 0 0 1 1 1 0 Herpesvirus UL41A adh_short_C2 PF13561.6 OAG41523.1 - 1.8e-55 188.1 0.7 2.2e-55 187.7 0.7 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG41523.1 - 5e-48 163.1 1.1 6.2e-48 162.9 1.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG41523.1 - 2.6e-09 37.3 0.7 1.5e-08 34.8 0.7 1.9 1 1 0 1 1 1 1 KR domain zf-HIT PF04438.16 OAG41524.1 - 1.1e-10 41.2 6.5 2.2e-10 40.2 6.5 1.5 1 0 0 1 1 1 1 HIT zinc finger DENN PF02141.21 OAG41525.1 - 1.7e-40 139.0 0.1 3.1e-40 138.1 0.1 1.5 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 OAG41525.1 - 1.6e-05 25.6 0.1 8.1e-05 23.3 0.0 2.3 2 0 0 2 2 2 1 uDENN domain SMC_Nse1 PF07574.13 OAG41525.1 - 0.11 12.3 5.1 0.33 10.8 5.1 1.8 1 1 0 1 1 1 0 Nse1 non-SMC component of SMC5-6 complex TRAF_BIRC3_bd PF16673.5 OAG41525.1 - 0.3 10.9 5.4 11 5.9 0.9 3.0 2 0 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain DivIC PF04977.15 OAG41525.1 - 0.73 9.6 17.6 5.3 6.9 1.7 3.7 2 1 1 3 3 3 0 Septum formation initiator FlaC_arch PF05377.11 OAG41525.1 - 2.1 8.8 4.2 50 4.4 0.1 3.6 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Cnn_1N PF07989.11 OAG41525.1 - 2.5 8.3 12.6 2.4 8.4 3.5 3.0 2 1 0 2 2 2 0 Centrosomin N-terminal motif 1 ADIP PF11559.8 OAG41525.1 - 3.7 7.6 18.9 1.4 9.0 5.4 2.8 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Atg14 PF10186.9 OAG41525.1 - 6.9 5.7 10.7 14 4.7 9.7 1.9 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 3HCDH_N PF02737.18 OAG41526.1 - 2.1e-22 79.9 0.0 5.8e-10 39.3 0.0 2.2 1 1 1 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 OAG41526.1 - 5.8e-11 42.9 0.0 1.1e-10 42.0 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Pkinase PF00069.25 OAG41527.1 - 6.1e-20 71.7 0.0 1.1e-19 70.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain HEAT PF02985.22 OAG41527.1 - 1e-11 44.0 4.7 0.085 13.2 0.0 7.1 7 0 0 7 7 7 4 HEAT repeat WD40 PF00400.32 OAG41527.1 - 9.8e-11 42.0 2.5 1.1e-06 29.2 0.1 4.9 4 0 0 4 4 4 1 WD domain, G-beta repeat HEAT_2 PF13646.6 OAG41527.1 - 1.2e-05 25.6 0.6 0.27 11.6 0.3 4.3 4 1 2 6 6 6 3 HEAT repeats Pkinase_Tyr PF07714.17 OAG41527.1 - 0.002 17.5 0.0 0.003 16.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_EZ PF13513.6 OAG41527.1 - 0.04 14.4 0.1 24 5.6 0.0 3.5 3 0 0 3 3 3 0 HEAT-like repeat Ge1_WD40 PF16529.5 OAG41527.1 - 0.09 11.7 0.0 0.17 10.8 0.0 1.4 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein RabGAP-TBC PF00566.18 OAG41528.1 - 2.9e-36 125.1 0.0 1.3e-35 123.0 0.0 1.9 2 0 0 2 2 2 1 Rab-GTPase-TBC domain TilS_C PF11734.8 OAG41528.1 - 0.037 13.5 0.4 0.099 12.1 0.0 1.9 2 0 0 2 2 2 0 TilS substrate C-terminal domain SNF2_N PF00176.23 OAG41529.1 - 8.7e-57 192.4 0.0 1.4e-56 191.7 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OAG41529.1 - 3e-09 37.2 0.0 8.2e-09 35.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG41529.1 - 1.1e-07 32.0 0.0 3.1e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 OAG41529.1 - 0.0005 19.9 0.0 0.0012 18.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_5 PF14634.6 OAG41529.1 - 0.0047 16.8 12.9 0.0047 16.8 12.9 2.2 3 0 0 3 3 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 OAG41529.1 - 0.029 14.4 7.5 0.074 13.1 7.5 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_3 PF13920.6 OAG41529.1 - 0.094 12.6 14.6 0.062 13.2 10.6 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) ERCC3_RAD25_C PF16203.5 OAG41529.1 - 0.12 11.6 0.0 0.31 10.2 0.0 1.6 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase zf-C3HC4 PF00097.25 OAG41529.1 - 0.28 11.1 13.3 0.67 9.9 13.3 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) CEBP_ZZ PF16366.5 OAG41529.1 - 0.47 10.7 8.2 1.1 9.5 8.2 1.6 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain zf-C3HC4_4 PF15227.6 OAG41529.1 - 0.76 10.0 11.3 1.8 8.8 11.3 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 OAG41529.1 - 0.83 9.6 2.8 2.1 8.3 2.8 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-piccolo PF05715.13 OAG41529.1 - 0.95 9.7 7.9 2.4 8.4 7.9 1.6 1 0 0 1 1 1 0 Piccolo Zn-finger zf-RING_2 PF13639.6 OAG41529.1 - 9.4 6.7 13.6 34 4.9 11.1 2.5 2 0 0 2 2 2 0 Ring finger domain IML1 PF12257.8 OAG41530.1 - 1.9e-113 378.3 0.0 2.9e-113 377.8 0.0 1.3 1 0 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 DEP PF00610.21 OAG41530.1 - 1.7e-26 92.1 0.2 3.5e-26 91.0 0.2 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) FNIP_N PF14636.6 OAG41530.1 - 3.6e-08 34.5 0.0 3.6e-08 34.5 0.0 6.9 7 1 0 7 7 7 1 Folliculin-interacting protein N-terminus FNIP_M PF14637.6 OAG41530.1 - 0.0021 18.1 0.1 0.0057 16.7 0.0 1.6 1 1 0 1 1 1 1 Folliculin-interacting protein middle domain NACHT PF05729.12 OAG41531.1 - 2.2e-19 70.0 0.0 1.1e-18 67.7 0.0 2.3 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.22 OAG41531.1 - 9.4e-07 28.3 0.0 2e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.6 OAG41531.1 - 2.9e-06 27.6 0.1 2.3e-05 24.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain NLRC4_HD2 PF17776.1 OAG41531.1 - 1.9e-05 25.2 0.4 0.0007 20.1 0.0 3.6 3 1 0 3 3 3 1 NLRC4 helical domain HD2 AAA_16 PF13191.6 OAG41531.1 - 2.8e-05 24.6 0.1 0.00022 21.7 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.6 OAG41531.1 - 0.0023 17.7 0.0 0.0054 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 OAG41531.1 - 0.01 16.2 0.0 0.027 14.8 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.6 OAG41531.1 - 0.014 14.9 0.0 0.78 9.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 OAG41531.1 - 0.033 13.9 0.0 0.087 12.6 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.6 OAG41531.1 - 0.034 14.7 0.0 0.1 13.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 OAG41531.1 - 0.035 14.2 0.0 0.26 11.3 0.0 2.5 2 1 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 OAG41531.1 - 0.045 13.7 0.0 0.095 12.6 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase ATPase_2 PF01637.18 OAG41531.1 - 0.083 12.8 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea DAP3 PF10236.9 OAG41531.1 - 0.085 12.0 0.0 1.1 8.4 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 DUF815 PF05673.13 OAG41531.1 - 0.099 11.8 0.0 0.22 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) MatP PF06303.12 OAG41531.1 - 0.1 13.2 1.2 0.4 11.3 0.3 2.4 2 0 0 2 2 2 0 MatP N-terminal domain GDA1_CD39 PF01150.17 OAG41532.1 - 4.5e-109 364.9 0.0 6.1e-109 364.5 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family COQ9 PF08511.11 OAG41532.1 - 0.055 13.2 0.1 0.11 12.3 0.1 1.4 1 0 0 1 1 1 0 COQ9 K_oxygenase PF13434.6 OAG41534.1 - 6.6e-15 55.1 0.0 2.3e-08 33.6 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 OAG41534.1 - 3e-08 33.3 0.0 0.025 13.8 0.0 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG41534.1 - 3.1e-06 26.7 0.0 0.0042 16.4 0.0 3.2 4 0 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAG41534.1 - 0.00047 20.2 0.3 0.013 15.5 0.0 2.8 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.24 OAG41534.1 - 0.00054 19.7 3.0 0.0042 16.7 0.3 3.2 3 1 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 OAG41534.1 - 0.013 14.7 1.5 0.083 12.1 0.3 2.4 2 1 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.12 OAG41534.1 - 0.016 14.3 1.9 0.021 13.9 0.0 2.1 3 0 0 3 3 3 0 Lycopene cyclase protein Pyr_redox PF00070.27 OAG41534.1 - 0.018 15.6 0.1 5.1 7.7 0.0 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG41534.1 - 0.038 14.2 1.4 0.15 12.3 0.0 2.4 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain ApbA PF02558.16 OAG41534.1 - 0.069 12.8 0.0 0.28 10.8 0.0 2.1 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Thi4 PF01946.17 OAG41534.1 - 0.09 12.0 0.1 0.22 10.8 0.1 1.6 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 OAG41534.1 - 0.1 11.3 0.0 0.66 8.6 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein NAD_Gly3P_dh_N PF01210.23 OAG41534.1 - 0.19 11.7 0.0 0.41 10.6 0.0 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Fungal_trans_2 PF11951.8 OAG41535.1 - 5.3e-57 193.4 0.3 8.7e-57 192.7 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG41535.1 - 7.7e-06 25.9 5.8 1.4e-05 25.2 5.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain XAP5 PF04921.14 OAG41536.1 - 3.2e-79 266.3 0.0 4.4e-79 265.8 0.0 1.2 1 0 0 1 1 1 1 XAP5, circadian clock regulator DUF4604 PF15377.6 OAG41536.1 - 0.0016 18.9 2.2 0.0016 18.9 2.2 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4604) zf-RING_5 PF14634.6 OAG41537.1 - 0.0083 16.1 0.8 0.0083 16.1 0.8 4.1 6 0 0 6 6 5 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 OAG41537.1 - 0.013 15.4 0.7 0.013 15.4 0.7 4.8 5 1 0 5 5 5 0 Zinc finger, C3HC4 type (RING finger) GIT_CC PF16559.5 OAG41537.1 - 0.015 15.1 3.5 0.044 13.6 3.5 1.8 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor FlaC_arch PF05377.11 OAG41537.1 - 0.033 14.6 0.5 0.081 13.3 0.5 1.6 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) 60KD_IMP PF02096.20 OAG41537.1 - 0.037 13.9 0.5 0.069 13.1 0.5 1.5 1 0 0 1 1 1 0 60Kd inner membrane protein Jnk-SapK_ap_N PF09744.9 OAG41537.1 - 0.039 14.2 12.0 0.064 13.5 12.0 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Spc24 PF08286.11 OAG41537.1 - 0.078 13.2 3.9 0.13 12.5 3.9 1.4 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 ADIP PF11559.8 OAG41537.1 - 0.091 12.8 10.2 0.18 11.9 10.2 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding zf-WRNIP1_ubi PF18279.1 OAG41537.1 - 0.097 13.4 0.2 0.44 11.3 0.2 2.2 1 0 0 1 1 1 0 Werner helicase-interacting protein 1 ubiquitin-binding domain DUF2730 PF10805.8 OAG41537.1 - 0.11 12.6 0.7 0.22 11.6 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) Flagellin_N PF00669.20 OAG41537.1 - 0.15 12.2 6.7 0.26 11.4 6.7 1.3 1 0 0 1 1 1 0 Bacterial flagellin N-terminal helical region Mod_r PF07200.13 OAG41537.1 - 0.15 12.1 10.6 0.27 11.3 10.6 1.4 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Tropomyosin_1 PF12718.7 OAG41537.1 - 0.19 11.8 10.8 0.78 9.9 8.8 2.0 1 1 1 2 2 2 0 Tropomyosin like DUF4407 PF14362.6 OAG41537.1 - 0.2 11.0 7.7 0.3 10.4 7.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CLZ PF16526.5 OAG41537.1 - 0.3 11.5 4.0 0.48 10.8 2.3 2.0 1 1 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels She9_MDM33 PF05546.11 OAG41537.1 - 0.33 10.7 7.2 0.51 10.1 7.2 1.2 1 0 0 1 1 1 0 She9 / Mdm33 family FPP PF05911.11 OAG41537.1 - 0.55 8.4 9.2 0.75 7.9 9.2 1.1 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil Exonuc_VII_L PF02601.15 OAG41537.1 - 0.57 9.7 7.3 0.89 9.1 7.3 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit IFT57 PF10498.9 OAG41537.1 - 0.58 9.1 9.8 0.87 8.5 9.8 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 FapA PF03961.13 OAG41537.1 - 0.73 8.4 3.0 1 7.9 3.0 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A LPP PF04728.13 OAG41537.1 - 0.76 10.2 5.7 0.97 9.9 2.5 2.4 1 1 1 2 2 2 0 Lipoprotein leucine-zipper MPS2 PF17060.5 OAG41537.1 - 1 8.6 6.0 1.5 8.0 6.0 1.1 1 0 0 1 1 1 0 Monopolar spindle protein 2 Ax_dynein_light PF10211.9 OAG41537.1 - 1.3 9.0 10.2 2 8.3 10.2 1.2 1 0 0 1 1 1 0 Axonemal dynein light chain Phage_GP20 PF06810.11 OAG41537.1 - 2.3 8.0 10.2 4.5 7.1 10.2 1.3 1 0 0 1 1 1 0 Phage minor structural protein GP20 TMF_DNA_bd PF12329.8 OAG41537.1 - 2.5 8.2 10.1 1.8 8.6 4.9 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding OmpH PF03938.14 OAG41537.1 - 5.9 7.2 16.3 12 6.2 16.3 1.4 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) FAD_binding_4 PF01565.23 OAG41538.1 - 7.8e-15 54.8 0.0 1.3e-14 54.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Fip1 PF05182.13 OAG41539.1 - 1.1e-22 79.2 1.0 2.9e-22 77.9 1.0 1.7 1 0 0 1 1 1 1 Fip1 motif Cpn10 PF00166.21 OAG41540.1 - 1.1e-26 92.6 0.0 1.3e-26 92.5 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Exo84_C PF16528.5 OAG41541.1 - 1.6e-60 204.4 0.5 1.6e-60 204.4 0.5 1.8 2 0 0 2 2 2 1 Exocyst component 84 C-terminal Vps51 PF08700.11 OAG41541.1 - 2.6e-16 59.5 2.4 7.6e-16 58.0 2.4 1.8 1 0 0 1 1 1 1 Vps51/Vps67 DUF4618 PF15397.6 OAG41541.1 - 0.07 12.5 4.9 0.051 13.0 2.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) APG6_N PF17675.1 OAG41541.1 - 1.1 9.8 12.5 2.3 8.8 0.7 2.7 3 0 0 3 3 3 0 Apg6 coiled-coil region AA_permease PF00324.21 OAG41542.1 - 1.2e-132 443.0 32.9 1.4e-132 442.7 32.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAG41542.1 - 4.4e-41 141.1 34.9 5.6e-41 140.7 34.9 1.0 1 0 0 1 1 1 1 Amino acid permease Glyco_hydro_1 PF00232.18 OAG41543.1 - 6.8e-76 255.5 2.8 1.7e-73 247.6 2.8 2.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 1 HET PF06985.11 OAG41544.1 - 3.8e-27 95.4 0.0 6.5e-27 94.7 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ABC2_membrane PF01061.24 OAG41545.1 - 7.2e-86 286.9 50.1 4.8e-46 156.8 19.2 2.7 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 OAG41545.1 - 1.4e-39 135.8 0.0 2e-17 64.0 0.0 3.5 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.12 OAG41545.1 - 3.7e-36 122.9 2.5 5.1e-31 106.4 0.1 3.1 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.6 OAG41545.1 - 1.3e-11 44.9 0.1 1.3e-11 44.9 0.1 2.3 2 0 0 2 2 2 1 ABC-transporter N-terminal AAA_25 PF13481.6 OAG41545.1 - 1.3e-06 28.2 0.2 1.8e-05 24.4 0.1 2.5 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OAG41545.1 - 2.2e-06 28.2 0.1 0.003 18.0 0.1 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 OAG41545.1 - 4.4e-06 26.7 0.0 0.086 12.6 0.0 3.4 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.6 OAG41545.1 - 2.7e-05 24.4 0.0 0.14 12.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 OAG41545.1 - 6.4e-05 22.6 1.0 0.0073 16.0 0.2 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 OAG41545.1 - 7.7e-05 22.7 0.1 0.0041 17.0 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase SMC_N PF02463.19 OAG41545.1 - 0.0002 20.9 0.0 0.55 9.6 0.0 3.8 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain ABC2_membrane_3 PF12698.7 OAG41545.1 - 0.0008 18.6 39.8 0.0025 17.0 13.2 2.5 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_22 PF13401.6 OAG41545.1 - 0.0032 17.7 0.5 0.91 9.8 0.1 3.2 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 OAG41545.1 - 0.0053 17.3 0.0 0.51 10.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 OAG41545.1 - 0.0068 16.0 0.9 0.23 11.0 0.1 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.6 OAG41545.1 - 0.0098 16.3 0.1 1.5 9.2 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_24 PF13479.6 OAG41545.1 - 0.035 13.8 0.4 7.7 6.2 0.2 2.6 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 OAG41545.1 - 0.037 14.5 0.4 0.17 12.4 0.0 2.3 3 0 0 3 3 2 0 AAA domain NACHT PF05729.12 OAG41545.1 - 0.073 13.0 0.7 4.5 7.2 0.3 2.7 2 0 0 2 2 2 0 NACHT domain AAA_30 PF13604.6 OAG41545.1 - 0.076 12.7 0.1 3.9 7.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain FdhD-NarQ PF02634.15 OAG41546.1 - 0.03 14.0 0.2 0.033 13.9 0.2 1.1 1 0 0 1 1 1 0 FdhD/NarQ family BsuBI_PstI_RE_N PF17728.1 OAG41547.1 - 0.027 14.3 0.4 0.064 13.1 0.2 1.7 2 0 0 2 2 2 0 BsuBI/PstI restriction endonuclease HTH domain DUF3425 PF11905.8 OAG41548.1 - 5.8e-12 45.7 0.0 1.1e-11 44.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 OAG41548.1 - 0.00052 20.1 11.3 0.0014 18.7 11.3 1.7 1 1 0 1 1 1 1 bZIP transcription factor Csm1_N PF18504.1 OAG41548.1 - 0.046 14.1 0.9 0.046 14.1 0.9 2.2 2 0 0 2 2 2 0 Csm1 N-terminal domain Seryl_tRNA_N PF02403.22 OAG41548.1 - 0.29 11.4 4.1 0.51 10.6 4.1 1.3 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain bZIP_2 PF07716.15 OAG41548.1 - 4.1 7.6 9.9 21 5.3 9.9 2.1 1 1 0 1 1 1 0 Basic region leucine zipper FMO-like PF00743.19 OAG41549.1 - 4.4e-14 51.8 0.4 3.9e-13 48.7 0.1 2.3 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OAG41549.1 - 1.1e-11 44.8 0.0 2.4e-11 43.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 OAG41549.1 - 7.9e-05 22.0 0.0 0.0028 16.9 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 OAG41549.1 - 0.00051 19.4 0.1 0.005 16.1 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAG41549.1 - 0.0019 18.2 0.0 0.33 10.9 0.0 2.7 3 0 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.17 OAG41549.1 - 0.017 14.4 0.0 0.061 12.6 0.0 1.8 2 0 0 2 2 2 0 Thi4 family Shikimate_DH PF01488.20 OAG41549.1 - 0.036 14.1 0.0 0.1 12.7 0.0 1.7 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase adh_short_C2 PF13561.6 OAG41550.1 - 1e-51 175.8 0.1 1.2e-51 175.6 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG41550.1 - 9.9e-45 152.4 0.1 1.2e-44 152.1 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG41550.1 - 1.9e-05 24.7 0.1 5e-05 23.3 0.1 1.7 1 1 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.8 OAG41550.1 - 0.13 12.1 0.5 0.34 10.7 0.5 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase TRI12 PF06609.13 OAG41551.1 - 1.8e-31 109.3 31.1 2.3e-31 108.9 31.1 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG41551.1 - 2.5e-17 62.8 55.0 2.5e-17 62.8 55.0 3.1 2 1 0 2 2 2 1 Major Facilitator Superfamily PalH PF08733.10 OAG41551.1 - 4.5 6.2 12.0 1.4 7.8 0.7 2.8 1 1 1 3 3 3 0 PalH/RIM21 FAD_oxidored PF12831.7 OAG41552.1 - 2e-67 228.4 3.5 5.1e-66 223.8 3.5 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase Ost4 PF10215.9 OAG41552.1 - 8.4e-18 63.9 2.8 1.5e-17 63.1 2.8 1.4 1 0 0 1 1 1 1 Oligosaccaryltransferase FAD_binding_2 PF00890.24 OAG41552.1 - 1.2e-05 24.6 4.1 3.1e-05 23.2 1.6 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 OAG41552.1 - 4e-05 24.1 1.0 0.00014 22.4 0.7 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAG41552.1 - 6.4e-05 22.3 0.0 9.9e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAG41552.1 - 0.00011 22.0 0.5 0.00035 20.3 0.4 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 OAG41552.1 - 0.00013 21.2 0.7 0.00019 20.6 0.7 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 OAG41552.1 - 0.0047 17.1 0.8 0.016 15.4 0.8 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DUF5329 PF17263.2 OAG41552.1 - 0.0084 16.3 0.2 0.017 15.3 0.2 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5329) AlaDh_PNT_C PF01262.21 OAG41552.1 - 0.021 14.1 1.3 0.046 13.0 1.3 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 OAG41552.1 - 0.03 13.0 0.3 0.05 12.3 0.3 1.3 1 0 0 1 1 1 0 HI0933-like protein CBM_35 PF16990.5 OAG41552.1 - 0.059 13.6 0.1 0.37 11.0 0.0 2.1 2 0 0 2 2 2 0 Carbohydrate binding module (family 35) Pyr_redox_3 PF13738.6 OAG41552.1 - 0.061 12.6 0.0 0.093 12.0 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAG41552.1 - 0.18 11.0 0.2 0.32 10.2 0.2 1.3 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.14 OAG41552.1 - 0.19 10.5 0.6 4.3 6.1 0.2 2.1 2 0 0 2 2 2 0 Tryptophan halogenase DUF4521 PF15021.6 OAG41553.1 - 5.9 6.8 8.2 0.47 10.3 1.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF4521) Ribosomal_L26 PF16906.5 OAG41554.1 - 5.1e-38 129.4 2.9 6.4e-38 129.1 2.9 1.1 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 OAG41554.1 - 1.7e-07 30.9 0.2 1.7e-07 30.9 0.2 1.8 2 0 0 2 2 2 1 KOW motif DUF1223 PF06764.11 OAG41554.1 - 0.18 11.8 0.1 0.19 11.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1223) MIP PF00230.20 OAG41555.1 - 4.2e-30 105.1 4.6 6.3e-30 104.6 4.6 1.2 1 0 0 1 1 1 1 Major intrinsic protein SKG6 PF08693.10 OAG41555.1 - 0.7 9.4 3.5 1.1 8.7 2.6 1.8 1 1 0 1 1 1 0 Transmembrane alpha-helix domain adh_short PF00106.25 OAG41556.1 - 2.9e-27 95.4 0.0 3.6e-27 95.1 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG41556.1 - 1.8e-22 80.0 0.0 2.4e-22 79.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG41556.1 - 1e-05 25.6 0.1 1.3e-05 25.2 0.1 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 OAG41556.1 - 0.036 13.4 0.0 0.05 13.0 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Sugar_tr PF00083.24 OAG41557.1 - 2.1e-80 270.8 26.1 2.5e-80 270.6 26.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG41557.1 - 9.5e-19 67.5 30.3 9.5e-19 67.5 30.3 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily DIE2_ALG10 PF04922.12 OAG41557.1 - 0.0088 15.4 0.1 0.017 14.4 0.1 1.4 1 0 0 1 1 1 1 DIE2/ALG10 family Acyltransferase PF01553.21 OAG41560.1 - 1.8e-17 63.2 0.0 3.8e-17 62.2 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase Peptidase_M24 PF00557.24 OAG41561.1 - 2.5e-22 79.6 0.0 2.9e-22 79.4 0.0 1.0 1 0 0 1 1 1 1 Metallopeptidase family M24 LRR_9 PF14580.6 OAG41562.1 - 3.4e-59 199.3 0.1 5.1e-59 198.7 0.1 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 OAG41562.1 - 1.3e-05 25.5 8.7 0.00013 22.2 0.3 3.6 3 2 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OAG41562.1 - 1.9e-05 24.3 4.0 2.8e-05 23.8 0.2 3.1 4 0 0 4 4 4 1 Leucine rich repeat HMG_box_5 PF14887.6 OAG41562.1 - 0.055 13.5 0.4 0.11 12.5 0.4 1.5 1 0 0 1 1 1 0 HMG (high mobility group) box 5 PrpR_N PF06506.11 OAG41562.1 - 0.08 12.5 0.1 0.15 11.6 0.1 1.4 1 0 0 1 1 1 0 Propionate catabolism activator LRR_6 PF13516.6 OAG41562.1 - 0.41 10.8 3.0 24 5.3 0.1 4.1 4 0 0 4 4 4 0 Leucine Rich repeat GATase PF00117.28 OAG41563.1 - 7.9e-10 38.8 0.0 1.2e-09 38.2 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 OAG41563.1 - 0.027 14.1 0.0 0.042 13.4 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain MFS_1 PF07690.16 OAG41564.1 - 5e-43 147.4 70.0 4.4e-39 134.4 45.6 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG41564.1 - 1.5e-12 47.1 12.1 1.5e-12 47.1 12.1 2.4 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 OAG41564.1 - 2.5e-07 29.5 12.3 2.5e-07 29.5 12.3 2.1 1 1 1 2 2 2 2 Fungal trichothecene efflux pump (TRI12) TPP_enzyme_N PF02776.18 OAG41565.1 - 9.6e-33 113.2 0.8 1.8e-32 112.4 0.8 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 OAG41565.1 - 7.6e-16 58.3 0.1 8e-14 51.7 0.0 2.8 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 OAG41565.1 - 3.6e-14 52.7 0.0 6.9e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain Na_Ca_ex PF01699.24 OAG41566.1 - 4.9e-44 149.9 38.0 4.4e-22 78.7 12.1 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein LRS4 PF10422.9 OAG41566.1 - 0.61 9.6 2.5 1.9 8.0 2.6 1.6 1 1 0 1 1 1 0 Monopolin complex subunit LRS4 HCV_core PF01542.18 OAG41566.1 - 1.6 9.2 5.2 0.48 10.8 0.9 2.2 2 0 0 2 2 2 0 Hepatitis C virus core protein ATP_bind_3 PF01171.20 OAG41567.1 - 6.6e-35 120.5 0.0 1.7e-34 119.2 0.0 1.7 1 1 0 1 1 1 1 PP-loop family DIOX_N PF14226.6 OAG41568.1 - 6.7e-16 59.1 0.0 1.1e-15 58.4 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OAG41568.1 - 1.3e-14 54.4 0.0 2.4e-14 53.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily RRN3 PF05327.11 OAG41569.1 - 6.7e-154 513.5 0.1 6.7e-154 513.5 0.1 1.3 2 0 0 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 DUF4559 PF15112.6 OAG41569.1 - 0.89 9.2 4.0 1.4 8.5 4.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) SIMPL PF04402.14 OAG41570.1 - 1.4e-25 91.0 0.0 1.6e-25 90.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF541) Sugar_tr PF00083.24 OAG41571.1 - 4.2e-80 269.8 24.1 4.8e-80 269.6 24.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG41571.1 - 9.1e-23 80.7 59.8 4.7e-21 75.1 35.5 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Fcf1 PF04900.12 OAG41573.1 - 4.8e-13 49.4 3.8 1.1e-11 45.0 3.8 2.7 1 1 0 1 1 1 1 Fcf1 Tmemb_14 PF03647.13 OAG41574.1 - 8.2e-25 87.4 8.2 9.7e-25 87.1 8.2 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C Aim19 PF10315.9 OAG41574.1 - 0.0021 18.3 1.0 0.0088 16.3 1.0 1.9 1 1 0 1 1 1 1 Altered inheritance of mitochondria protein 19 GMC_oxred_N PF00732.19 OAG41575.1 - 1.1e-56 192.4 0.0 1.5e-56 191.9 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAG41575.1 - 3.5e-33 115.1 0.0 7.1e-33 114.2 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 OAG41575.1 - 8.2e-05 22.8 1.5 0.00021 21.5 1.5 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAG41575.1 - 0.014 14.7 0.1 0.13 11.5 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OAG41575.1 - 0.015 14.4 0.4 0.023 13.7 0.4 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_2 PF00890.24 OAG41575.1 - 0.017 14.2 1.4 0.017 14.2 1.4 1.6 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_3 PF13738.6 OAG41575.1 - 0.15 11.3 0.3 0.32 10.2 0.1 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAG41575.1 - 0.33 10.5 3.4 0.16 11.5 0.7 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase DAD PF02109.16 OAG41576.1 - 2.6e-43 146.8 0.3 4.1e-43 146.1 0.3 1.3 1 1 0 1 1 1 1 DAD family SET PF00856.28 OAG41577.1 - 1.3e-10 41.9 0.2 1.3e-09 38.6 0.0 2.5 2 1 0 2 2 2 1 SET domain Fungal_trans PF04082.18 OAG41578.1 - 1.4e-59 201.3 0.0 2.6e-59 200.4 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 OAG41578.1 - 0.0027 18.1 2.9 0.0027 18.1 2.9 2.5 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OAG41578.1 - 0.046 14.2 11.3 0.024 15.1 4.0 2.8 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 OAG41578.1 - 1.4 9.9 8.4 0.23 12.4 2.4 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger GFA PF04828.14 OAG41579.1 - 0.00022 21.5 0.1 0.00034 20.9 0.1 1.4 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zf-NADH-PPase PF09297.11 OAG41579.1 - 0.18 11.5 0.6 0.18 11.5 0.6 1.6 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Rot1 PF10681.9 OAG41580.1 - 4.2e-93 310.7 0.2 4.9e-93 310.4 0.2 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal 5-FTHF_cyc-lig PF01812.20 OAG41581.1 - 7.8e-31 107.4 0.0 1.4e-30 106.6 0.0 1.4 1 1 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family Xpo1 PF08389.12 OAG41582.1 - 1.3e-26 93.4 0.2 9.4e-26 90.7 0.0 2.6 3 0 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.19 OAG41582.1 - 7.9e-05 22.5 0.2 0.00031 20.6 0.0 2.1 2 0 0 2 2 2 1 Importin-beta N-terminal domain UME PF08064.13 OAG41582.1 - 0.04 13.8 0.5 2.8 7.9 0.0 3.8 3 0 0 3 3 3 0 UME (NUC010) domain Importin_rep_3 PF18806.1 OAG41582.1 - 0.087 12.9 0.0 0.41 10.7 0.0 2.2 1 0 0 1 1 1 0 Importin 13 repeat HEAT PF02985.22 OAG41582.1 - 0.13 12.6 1.2 24 5.5 0.0 4.3 3 0 0 3 3 3 0 HEAT repeat CorA PF01544.18 OAG41583.1 - 3e-06 26.8 0.5 3e-06 26.8 0.5 1.7 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein Ni_hydr_CYTB PF01292.20 OAG41583.1 - 0.002 17.7 1.0 0.0031 17.1 0.1 1.8 2 0 0 2 2 2 1 Prokaryotic cytochrome b561 Sas10_Utp3 PF04000.15 OAG41584.1 - 0.19 12.3 0.1 0.4 11.3 0.1 1.5 1 0 0 1 1 1 0 Sas10/Utp3/C1D family Mito_carr PF00153.27 OAG41585.1 - 3.5e-50 167.9 3.1 2e-18 66.1 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein zf-ZPR1 PF03367.13 OAG41587.1 - 7.1e-106 351.0 0.0 9.9e-57 191.2 0.0 2.1 2 0 0 2 2 2 2 ZPR1 zinc-finger domain zinc-ribbons_6 PF07191.12 OAG41587.1 - 0.1 12.6 3.0 0.75 9.8 0.5 2.3 2 0 0 2 2 2 0 zinc-ribbons Terminase_GpA PF05876.12 OAG41587.1 - 0.18 10.3 0.2 0.28 9.7 0.2 1.2 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) HypA PF01155.19 OAG41587.1 - 0.23 11.5 3.2 1.8 8.6 0.5 2.4 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Lar_restr_allev PF14354.6 OAG41587.1 - 0.3 11.5 7.5 1.1 9.7 1.5 2.6 2 1 0 2 2 2 0 Restriction alleviation protein Lar zf-ribbon_3 PF13248.6 OAG41587.1 - 0.3 10.6 10.5 6.8 6.3 1.7 3.5 3 0 0 3 3 3 0 zinc-ribbon domain E7 PF00527.18 OAG41587.1 - 0.4 10.9 9.1 0.41 10.9 0.5 2.8 3 0 0 3 3 3 0 E7 protein, Early protein Rubredoxin_2 PF18073.1 OAG41587.1 - 7.2 6.4 12.2 6 6.7 0.2 3.4 3 0 0 3 3 3 0 Rubredoxin metal binding domain Fungal_trans_2 PF11951.8 OAG41588.1 - 0.0017 17.2 1.1 0.23 10.2 0.0 2.4 2 0 0 2 2 2 2 Fungal specific transcription factor domain ADH_zinc_N PF00107.26 OAG41589.1 - 2.8e-24 85.5 0.6 4.8e-24 84.8 0.6 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG41589.1 - 4.7e-22 77.9 0.0 9e-22 77.0 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Fungal_trans PF04082.18 OAG41589.1 - 2e-16 59.8 0.8 3.7e-16 58.9 0.8 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain PAAR_motif PF05488.13 OAG41589.1 - 0.07 13.3 1.4 0.32 11.2 0.4 2.3 2 0 0 2 2 2 0 PAAR motif Abhydrolase_3 PF07859.13 OAG41590.1 - 1.3e-20 74.2 0.0 2.8e-20 73.1 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 OAG41590.1 - 9.4e-11 41.2 0.0 1.5e-10 40.6 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase FMO-like PF00743.19 OAG41591.1 - 3.7e-14 52.1 0.0 8.2e-13 47.6 0.0 2.4 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OAG41591.1 - 2.4e-13 50.1 0.0 6.2e-13 48.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAG41591.1 - 3.5e-05 23.2 0.0 0.0068 15.7 0.0 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAG41591.1 - 0.00033 20.4 0.0 0.16 11.5 0.0 2.9 1 1 2 3 3 3 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 OAG41591.1 - 0.0011 19.0 0.0 0.012 15.6 0.0 2.7 3 0 0 3 3 3 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 OAG41591.1 - 0.0067 15.6 0.0 4.4 6.4 0.0 3.6 4 0 0 4 4 4 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 OAG41591.1 - 0.011 15.1 0.0 0.025 13.8 0.0 1.5 2 0 0 2 2 2 0 Thi4 family Pyr_redox_3 PF13738.6 OAG41591.1 - 0.035 13.4 0.0 0.42 9.8 0.0 2.4 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase p450 PF00067.22 OAG41592.1 - 6.8e-57 193.2 0.0 8.5e-57 192.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.25 OAG41593.1 - 1.6e-22 80.0 0.5 9.4e-21 74.2 0.5 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG41593.1 - 1.2e-18 67.6 0.1 1.7e-16 60.5 0.1 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase PhyH PF05721.13 OAG41595.1 - 4.4e-16 59.8 0.0 6.3e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 OAG41595.1 - 0.15 10.8 0.1 0.34 9.6 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1479) UNC-93 PF05978.16 OAG41596.1 - 8.5e-08 32.1 6.8 3e-07 30.3 6.8 1.9 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 LAB_N PF07578.11 OAG41596.1 - 0.00037 20.5 1.3 0.0075 16.3 0.6 2.9 2 0 0 2 2 2 1 Lipid A Biosynthesis N-terminal domain DUF1294 PF06961.13 OAG41596.1 - 0.03 14.6 0.6 4.2 7.7 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1294) Sigma_reg_N PF13800.6 OAG41596.1 - 0.47 10.8 2.8 6.6 7.1 0.1 2.8 3 0 0 3 3 3 0 Sigma factor regulator N-terminal DUF4231 PF14015.6 OAG41596.1 - 0.89 10.1 9.8 0.54 10.7 0.4 3.8 5 0 0 5 5 5 0 Protein of unknown function (DUF4231) DUF4044 PF13253.6 OAG41596.1 - 7.4 6.2 8.8 1.2 8.7 4.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4044) Fungal_trans PF04082.18 OAG41597.1 - 4.6e-21 75.0 0.2 6.4e-21 74.6 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ribonuc_L-PSP PF01042.21 OAG41597.1 - 3.1e-14 53.0 0.0 8.8e-14 51.6 0.0 1.7 2 0 0 2 2 2 1 Endoribonuclease L-PSP Dicer_dimer PF03368.14 OAG41597.1 - 0.12 12.5 0.0 0.62 10.3 0.0 2.1 2 0 0 2 2 2 0 Dicer dimerisation domain PhyH PF05721.13 OAG41598.1 - 1.5e-16 61.3 0.0 4.3e-16 59.8 0.0 1.7 2 0 0 2 2 2 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 OAG41598.1 - 0.013 14.3 0.0 0.019 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1479) Peptidase_S15 PF02129.18 OAG41599.1 - 0.03 13.9 0.4 0.037 13.6 0.4 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) EPF PF17181.4 OAG41599.1 - 0.052 13.5 0.3 0.83 9.7 0.1 2.4 2 0 0 2 2 2 0 Epidermal patterning factor proteins 2OG-FeII_Oxy_3 PF13640.6 OAG41600.1 - 0.011 16.6 0.0 0.019 15.8 0.0 1.4 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Fungal_trans_2 PF11951.8 OAG41601.1 - 1.1e-24 86.9 2.7 1.5e-22 80.0 2.7 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Aminotran_1_2 PF00155.21 OAG41602.1 - 1.8e-15 57.0 0.0 2.4e-15 56.6 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 OAG41602.1 - 2.6e-05 23.2 0.0 3.7e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase AA_permease PF00324.21 OAG41603.1 - 3.2e-104 349.2 41.1 3.8e-104 348.9 41.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAG41603.1 - 9.3e-27 93.9 44.7 1.2e-26 93.6 44.7 1.1 1 0 0 1 1 1 1 Amino acid permease DUF3671 PF12420.8 OAG41603.1 - 5.1 7.2 7.4 57 3.8 1.0 3.5 3 0 0 3 3 3 0 Protein of unknown function TPP_enzyme_N PF02776.18 OAG41604.1 - 1.1e-31 109.8 0.1 1.7e-31 109.1 0.1 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 OAG41604.1 - 5.2e-18 65.3 0.0 6.9e-17 61.6 0.0 2.4 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 OAG41604.1 - 1.2e-15 57.5 0.0 2.2e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain AtuA PF07287.11 OAG41605.1 - 3.9e-126 420.5 0.0 5e-126 420.1 0.0 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA AtuA PF07287.11 OAG41606.1 - 1.6e-122 408.6 0.1 1.9e-122 408.4 0.1 1.0 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA Sec63 PF02889.16 OAG41610.1 - 6.7e-123 408.9 0.0 2e-78 263.1 0.3 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 OAG41610.1 - 7.4e-52 175.6 0.8 5.1e-27 94.8 0.8 2.9 3 0 0 3 3 2 2 DEAD/DEAH box helicase ResIII PF04851.15 OAG41610.1 - 2.2e-22 79.9 0.0 7.1e-11 42.4 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 OAG41610.1 - 8.3e-15 55.1 0.0 1.3e-06 28.7 0.0 4.2 3 2 0 3 3 3 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 OAG41610.1 - 1.5e-07 31.8 0.1 0.0089 16.3 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_30 PF13604.6 OAG41610.1 - 7.5e-07 29.1 0.1 0.027 14.2 0.3 2.6 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 OAG41610.1 - 6.2e-06 26.6 1.5 0.0046 17.3 0.9 3.1 3 0 0 3 3 3 2 AAA domain Helicase_PWI PF18149.1 OAG41610.1 - 0.00044 20.4 0.0 0.0014 18.8 0.0 1.9 1 0 0 1 1 1 1 N-terminal helicase PWI domain AAA PF00004.29 OAG41610.1 - 0.0031 17.9 0.1 5.1 7.5 0.0 4.0 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 OAG41610.1 - 0.011 14.8 0.0 1.2 8.1 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein IstB_IS21 PF01695.17 OAG41610.1 - 0.059 13.1 0.2 10 5.8 0.0 3.3 4 0 0 4 4 4 0 IstB-like ATP binding protein DUF2286 PF10051.9 OAG41610.1 - 0.11 12.2 0.1 0.97 9.2 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2286) Radial_spoke_3 PF06098.11 OAG41610.1 - 0.13 11.5 1.3 16 4.7 0.8 2.4 2 0 0 2 2 2 0 Radial spoke protein 3 Synaptobrevin PF00957.21 OAG41611.1 - 4.2e-14 52.1 0.4 7.2e-14 51.4 0.4 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 OAG41611.1 - 3.4e-10 39.8 0.0 5.9e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Acetyltransf_1 PF00583.25 OAG41612.1 - 4.5e-20 72.0 0.0 6.1e-20 71.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OAG41612.1 - 4.1e-09 36.7 0.0 7.3e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OAG41612.1 - 2.4e-07 30.7 0.0 3.8e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAG41612.1 - 1.4e-06 28.2 0.0 2.3e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 OAG41612.1 - 8.2e-05 23.3 0.0 0.00012 22.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 OAG41612.1 - 0.0016 18.5 0.0 0.012 15.7 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 OAG41612.1 - 0.0048 17.0 0.0 0.0095 16.1 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Fungal_trans_2 PF11951.8 OAG41613.1 - 0.0081 15.0 0.2 0.083 11.7 0.0 2.1 2 1 0 2 2 2 1 Fungal specific transcription factor domain adh_short PF00106.25 OAG41614.1 - 1.1e-31 109.8 1.0 1.4e-31 109.5 1.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG41614.1 - 1.8e-24 86.6 0.2 2.3e-24 86.2 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 OAG41614.1 - 1.8e-07 31.3 0.2 2.6e-07 30.7 0.2 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 OAG41614.1 - 5.7e-06 26.1 0.5 8.1e-06 25.6 0.5 1.2 1 0 0 1 1 1 1 NmrA-like family KR PF08659.10 OAG41614.1 - 0.012 15.5 0.2 0.018 15.0 0.2 1.3 1 0 0 1 1 1 0 KR domain Rossmann-like PF10727.9 OAG41614.1 - 0.014 15.3 0.6 0.028 14.3 0.6 1.5 1 0 0 1 1 1 0 Rossmann-like domain NAD_binding_2 PF03446.15 OAG41614.1 - 0.059 13.5 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Epimerase PF01370.21 OAG41614.1 - 0.11 11.9 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Brr6_like_C_C PF10104.9 OAG41615.1 - 1.6e-45 154.1 1.9 2.1e-45 153.7 1.9 1.1 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain DNA_binding_1 PF01035.20 OAG41616.1 - 2.6e-23 82.0 0.0 3.3e-23 81.6 0.0 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Bud13 PF09736.9 OAG41618.1 - 3.4e-48 163.7 9.2 3.4e-48 163.7 9.2 3.1 3 1 0 3 3 3 1 Pre-mRNA-splicing factor of RES complex HSP70 PF00012.20 OAG41619.1 - 0.014 13.6 0.0 0.02 13.1 0.0 1.2 1 0 0 1 1 1 0 Hsp70 protein MreB_Mbl PF06723.13 OAG41619.1 - 0.022 13.6 0.5 0.15 10.8 0.2 2.1 2 0 0 2 2 2 0 MreB/Mbl protein StbA PF06406.11 OAG41619.1 - 0.11 11.8 0.1 0.24 10.6 0.1 1.5 1 0 0 1 1 1 0 StbA protein Hydantoinase_A PF01968.18 OAG41619.1 - 0.11 11.7 0.1 2.1 7.5 0.1 2.1 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase SKG6 PF08693.10 OAG41620.1 - 0.032 13.6 0.0 0.081 12.3 0.0 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Rax2 PF12768.7 OAG41620.1 - 0.06 12.8 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Peptidase_M9_N PF08453.10 OAG41620.1 - 0.08 12.6 0.3 3.3 7.4 0.1 2.3 2 0 0 2 2 2 0 Peptidase family M9 N-terminal LapA_dom PF06305.11 OAG41620.1 - 0.14 12.0 0.1 0.31 10.9 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain TMEM154 PF15102.6 OAG41620.1 - 7.3 6.5 9.4 2.9e+02 1.3 9.4 2.5 1 1 0 1 1 1 0 TMEM154 protein family MGC-24 PF05283.11 OAG41622.1 - 0.0012 19.3 15.2 0.04 14.4 7.8 2.3 1 1 1 2 2 2 2 Multi-glycosylated core protein 24 (MGC-24), sialomucin Syndecan PF01034.20 OAG41622.1 - 0.002 18.0 0.0 0.0052 16.7 0.0 1.7 1 0 0 1 1 1 1 Syndecan domain Mid2 PF04478.12 OAG41622.1 - 0.13 12.1 0.0 0.13 12.1 0.0 1.8 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor DUF2207 PF09972.9 OAG41622.1 - 0.15 10.8 0.0 0.2 10.4 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Yip1 PF04893.17 OAG41622.1 - 2.5 7.8 5.9 0.3 10.8 1.4 1.8 2 1 0 2 2 2 0 Yip1 domain MSA-2c PF12238.8 OAG41622.1 - 5.5 6.9 12.1 8 6.4 12.1 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c CoA_transf_3 PF02515.17 OAG41623.1 - 3e-96 322.7 0.1 3.9e-96 322.4 0.1 1.1 1 0 0 1 1 1 1 CoA-transferase family III Fungal_trans PF04082.18 OAG41624.1 - 2.4e-08 33.3 0.3 4e-08 32.6 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain p450 PF00067.22 OAG41625.1 - 4.9e-61 206.9 0.0 6.3e-61 206.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SnoaL_4 PF13577.6 OAG41626.1 - 1.4e-12 47.8 3.3 1.8e-12 47.5 3.3 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_2 PF12680.7 OAG41626.1 - 1.7e-05 25.4 1.2 2.6e-05 24.8 1.0 1.4 1 1 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 OAG41626.1 - 0.00099 19.5 0.6 0.0013 19.1 0.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) Ring_hydroxyl_B PF00866.18 OAG41626.1 - 0.0057 16.7 0.4 0.3 11.2 0.0 2.2 1 1 1 2 2 2 1 Ring hydroxylating beta subunit FAD_binding_3 PF01494.19 OAG41627.1 - 3.6e-48 164.6 0.0 5.1e-48 164.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain HET PF06985.11 OAG41627.1 - 2.6e-22 79.8 0.0 1.4e-21 77.4 0.0 2.1 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DAO PF01266.24 OAG41627.1 - 7.1e-05 22.5 0.0 0.0013 18.4 0.0 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAG41627.1 - 0.00021 21.4 0.1 0.00059 20.0 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 OAG41627.1 - 0.00051 18.9 0.0 0.0035 16.1 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.14 OAG41627.1 - 0.00078 18.8 0.4 0.0048 16.2 0.0 2.4 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAG41627.1 - 0.0015 17.7 0.0 0.0033 16.6 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 OAG41627.1 - 0.007 15.5 0.0 0.084 11.9 0.0 2.3 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_oxidored PF12831.7 OAG41627.1 - 0.011 15.1 0.1 0.04 13.3 0.1 1.9 1 1 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 OAG41627.1 - 0.022 14.0 0.0 0.071 12.4 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAG41627.1 - 0.057 14.0 0.2 0.81 10.3 0.0 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAG41627.1 - 0.086 12.1 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.22 OAG41627.1 - 0.2 10.7 0.0 0.3 10.1 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A DUF383 PF04063.14 OAG41630.1 - 8.3e-67 224.6 0.5 5.2e-66 222.0 0.0 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF383) DUF384 PF04064.13 OAG41630.1 - 5.8e-23 80.5 3.3 8.4e-23 80.0 2.3 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF384) DUF3361 PF11841.8 OAG41630.1 - 0.01 15.8 0.2 0.02 14.8 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3361) Mic1 PF07035.12 OAG41630.1 - 0.086 12.6 0.3 0.15 11.7 0.3 1.3 1 0 0 1 1 1 0 Colon cancer-associated protein Mic1-like Cnd1 PF12717.7 OAG41630.1 - 0.24 11.4 3.1 0.59 10.2 3.0 1.6 1 1 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 PI3_PI4_kinase PF00454.27 OAG41631.1 - 5.9e-54 183.5 0.1 1.2e-53 182.5 0.1 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 OAG41631.1 - 1e-37 130.1 0.5 6.8e-37 127.5 0.5 2.4 2 0 0 2 2 2 1 FAT domain UME PF08064.13 OAG41631.1 - 5.9e-30 103.2 1.1 2.4e-29 101.2 0.0 2.8 3 0 0 3 3 3 1 UME (NUC010) domain FATC PF02260.20 OAG41631.1 - 3.6e-14 52.3 0.0 1.1e-13 50.7 0.0 2.0 2 0 0 2 2 2 1 FATC domain TPR_14 PF13428.6 OAG41631.1 - 0.029 15.2 7.4 12 7.1 0.0 5.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_15 PF13429.6 OAG41631.1 - 0.037 13.3 3.9 0.15 11.2 0.2 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Mod_r PF07200.13 OAG41631.1 - 0.05 13.7 3.7 0.43 10.7 0.2 2.9 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein TPR_19 PF14559.6 OAG41631.1 - 0.98 10.0 4.4 1.8 9.2 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Swi3 PF07962.12 OAG41632.1 - 1e-29 102.3 0.2 1.7e-29 101.6 0.2 1.4 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 NADH_u_ox_C PF12853.7 OAG41633.1 - 8.4e-25 86.6 0.1 1.2e-24 86.1 0.1 1.2 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit NADH-u_ox-rdase PF10785.9 OAG41633.1 - 6.7e-14 52.3 0.6 1.8e-13 51.0 0.6 1.7 1 1 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit HET PF06985.11 OAG41635.1 - 1e-23 84.3 0.0 2e-23 83.4 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PRKCSH-like PF12999.7 OAG41637.1 - 6.7e-44 149.8 5.7 3.9e-26 91.9 0.6 2.8 2 0 0 2 2 2 2 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 OAG41637.1 - 6.1e-31 107.2 0.9 3e-30 104.9 0.2 2.2 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 OAG41637.1 - 8.2e-11 42.8 0.3 2.2e-10 41.4 0.3 1.8 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein ATG27 PF09451.10 OAG41637.1 - 0.00052 20.0 0.3 0.00052 20.0 0.3 1.8 2 0 0 2 2 2 1 Autophagy-related protein 27 Cyclin_N2 PF16500.5 OAG41637.1 - 0.099 13.4 1.1 0.25 12.1 1.1 1.6 1 0 0 1 1 1 0 N-terminal region of cyclin_N DNA_pol3_beta_3 PF02768.15 OAG41637.1 - 0.26 11.1 3.3 0.47 10.3 3.3 1.3 1 0 0 1 1 1 0 DNA polymerase III beta subunit, C-terminal domain MutS_IV PF05190.18 OAG41637.1 - 0.36 11.2 3.7 2.2 8.7 1.0 2.6 2 0 0 2 2 2 0 MutS family domain IV Fib_alpha PF08702.10 OAG41637.1 - 1.7 8.8 7.2 4.8 7.4 1.6 3.0 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Ldl_recept_a PF00057.18 OAG41637.1 - 3.6 7.9 12.6 0.34 11.2 1.3 2.8 2 0 0 2 2 2 0 Low-density lipoprotein receptor domain class A Snapin_Pallidin PF14712.6 OAG41637.1 - 6 7.4 12.2 17 5.9 0.0 2.8 3 0 0 3 3 3 0 Snapin/Pallidin Hydrophobin PF01185.18 OAG41638.1 - 3.2e-09 37.3 12.7 4.6e-09 36.8 12.7 1.2 1 0 0 1 1 1 1 Fungal hydrophobin F-box-like PF12937.7 OAG41639.1 - 0.0074 16.2 0.4 0.026 14.4 0.1 2.2 2 0 0 2 2 2 1 F-box-like Fungal_TACC PF12709.7 OAG41640.1 - 2.2e-08 34.4 6.1 2.2e-08 34.4 6.1 4.5 3 2 0 3 3 3 2 Fungal Transforming acidic coiled-coil (TACC) proteins DUF745 PF05335.13 OAG41640.1 - 0.012 15.4 6.9 0.012 15.4 6.9 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF745) CT_C_D PF02682.16 OAG41640.1 - 0.1 12.3 0.0 0.28 10.9 0.0 1.8 1 0 0 1 1 1 0 Carboxyltransferase domain, subdomain C and D DUF4407 PF14362.6 OAG41640.1 - 0.14 11.5 24.2 0.59 9.4 7.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Mod_r PF07200.13 OAG41640.1 - 6.6 6.8 27.3 2.2 8.4 4.7 2.9 2 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Fez1 PF06818.15 OAG41640.1 - 7.2 7.0 36.4 2.4 8.6 15.1 2.4 2 0 0 2 2 2 0 Fez1 Lyase_1 PF00206.20 OAG41642.1 - 1.5e-40 139.6 0.0 2.1e-40 139.1 0.0 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 OAG41642.1 - 1.8e-19 70.1 0.0 4.6e-19 68.7 0.0 1.8 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus GST_C_3 PF14497.6 OAG41643.1 - 7.5e-31 106.3 0.1 1.6e-30 105.2 0.1 1.5 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OAG41643.1 - 2.1e-06 27.9 0.0 3.9e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OAG41643.1 - 0.0048 16.9 0.0 0.012 15.6 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glyco_hydro_127 PF07944.12 OAG41645.1 - 1.7e-107 360.1 0.0 2.1e-107 359.8 0.0 1.1 1 0 0 1 1 1 1 Beta-L-arabinofuranosidase, GH127 MFS_1 PF07690.16 OAG41646.1 - 8e-10 38.2 26.3 1.3e-09 37.5 26.3 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 OAG41646.1 - 4.8e-06 26.4 3.0 4.8e-06 26.4 3.0 2.5 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 Bac_luciferase PF00296.20 OAG41647.1 - 5.2e-56 190.4 1.9 8.5e-56 189.7 1.9 1.2 1 0 0 1 1 1 1 Luciferase-like monooxygenase adh_short PF00106.25 OAG41648.1 - 7.2e-20 71.3 0.2 6.3e-14 51.9 0.1 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAG41648.1 - 1.1e-12 48.0 0.0 2.6e-09 37.0 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG41648.1 - 0.0037 17.2 0.3 0.0056 16.6 0.3 1.3 1 0 0 1 1 1 1 KR domain FAD_binding_3 PF01494.19 OAG41649.1 - 2.1e-12 47.0 0.9 1.4e-07 31.2 0.2 3.0 2 1 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 OAG41649.1 - 8.7e-07 28.5 0.3 0.00026 20.3 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAG41649.1 - 4e-06 26.2 0.0 6.6e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 OAG41649.1 - 1.3e-05 25.3 0.0 3.7e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 OAG41649.1 - 0.00022 20.4 0.1 0.00035 19.8 0.1 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.14 OAG41649.1 - 0.00038 19.3 0.0 0.0012 17.7 0.0 1.7 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 OAG41649.1 - 0.00058 19.3 0.1 0.0014 18.1 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 OAG41649.1 - 0.0017 18.8 0.1 0.059 13.9 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 OAG41649.1 - 0.019 14.3 0.1 0.034 13.4 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 OAG41649.1 - 0.023 14.3 0.7 0.055 13.0 0.3 1.8 1 1 1 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 OAG41649.1 - 0.033 13.4 0.1 0.14 11.4 0.0 1.9 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase XPG_I_2 PF12813.7 OAG41650.1 - 7.8e-44 150.0 0.0 1.2e-43 149.4 0.0 1.3 1 0 0 1 1 1 1 XPG domain containing XPG_I PF00867.18 OAG41650.1 - 0.0083 16.5 0.0 0.021 15.2 0.0 1.6 1 0 0 1 1 1 1 XPG I-region DUF4851 PF16143.5 OAG41650.1 - 0.18 11.3 0.1 0.33 10.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4851) NAD_binding_4 PF07993.12 OAG41651.1 - 3.2e-41 141.2 0.0 8.4e-41 139.8 0.0 1.7 2 0 0 2 2 2 1 Male sterility protein AMP-binding PF00501.28 OAG41651.1 - 1.8e-31 109.2 0.0 4.1e-31 108.0 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 OAG41651.1 - 4.4e-10 39.4 0.0 9.6e-10 38.3 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 OAG41651.1 - 2.3e-08 34.3 0.1 5.5e-08 33.1 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site AAA_18 PF13238.6 OAG41651.1 - 9.6e-06 26.2 0.1 8.5e-05 23.1 0.1 2.9 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 OAG41651.1 - 9.8e-05 22.5 0.0 0.00042 20.5 0.0 2.2 1 0 0 1 1 1 1 AAA domain KR PF08659.10 OAG41651.1 - 0.0012 18.8 0.0 0.0051 16.7 0.0 2.1 1 0 0 1 1 1 1 KR domain SKI PF01202.22 OAG41651.1 - 0.0013 18.8 0.0 0.0056 16.8 0.0 2.1 2 0 0 2 2 2 1 Shikimate kinase AAA_17 PF13207.6 OAG41651.1 - 0.0017 18.8 0.0 0.0064 16.9 0.0 2.1 1 1 0 1 1 1 1 AAA domain 3Beta_HSD PF01073.19 OAG41651.1 - 0.0021 17.2 0.0 0.02 13.9 0.0 2.1 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Cytidylate_kin PF02224.18 OAG41651.1 - 0.003 17.3 2.1 0.0063 16.3 0.0 2.6 4 0 0 4 4 4 1 Cytidylate kinase AAA_16 PF13191.6 OAG41651.1 - 0.01 16.3 0.1 0.047 14.1 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain GDP_Man_Dehyd PF16363.5 OAG41651.1 - 0.02 14.3 0.0 0.21 10.9 0.0 2.1 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 OAG41651.1 - 0.027 14.4 0.1 0.065 13.1 0.1 1.6 1 0 0 1 1 1 0 NAD(P)H-binding Polysacc_synt_2 PF02719.15 OAG41651.1 - 0.027 13.6 0.0 0.048 12.8 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Rad17 PF03215.15 OAG41651.1 - 0.053 13.4 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain NmrA PF05368.13 OAG41651.1 - 0.13 11.8 0.1 0.24 10.9 0.1 1.4 1 0 0 1 1 1 0 NmrA-like family MFS_1 PF07690.16 OAG41652.1 - 3.9e-35 121.4 56.6 3.9e-35 121.4 56.6 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 OAG41652.1 - 9.1e-16 57.4 18.4 9.1e-16 57.4 18.4 1.4 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Oxidored_q2 PF00420.24 OAG41652.1 - 0.59 9.8 0.0 0.59 9.8 0.0 4.6 4 1 1 5 5 5 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Fungal_trans PF04082.18 OAG41654.1 - 2.3e-28 99.0 0.9 3.7e-28 98.3 0.9 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Acyl-CoA_dh_2 PF08028.11 OAG41654.1 - 0.036 14.3 0.0 0.086 13.1 0.0 1.6 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain Aldo_ket_red PF00248.21 OAG41655.1 - 1.1e-51 175.8 0.0 6.7e-51 173.2 0.0 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family HTH_26 PF13443.6 OAG41655.1 - 0.14 12.6 0.0 0.38 11.2 0.0 1.7 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain HlyIII PF03006.20 OAG41656.1 - 1.2e-52 178.8 19.7 1.5e-52 178.6 19.7 1.1 1 0 0 1 1 1 1 Haemolysin-III related SnAC PF14619.6 OAG41656.1 - 0.0076 16.8 0.0 0.012 16.2 0.0 1.2 1 0 0 1 1 1 1 Snf2-ATP coupling, chromatin remodelling complex DUF2964 PF11177.8 OAG41656.1 - 0.22 11.7 2.6 19 5.6 0.2 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2964) MaoC_dehydratas PF01575.19 OAG41657.1 - 1.1e-10 41.2 0.0 1.8e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain RibD_C PF01872.17 OAG41658.1 - 2.3e-29 102.6 0.0 5.2e-29 101.5 0.0 1.6 1 0 0 1 1 1 1 RibD C-terminal domain RRM_1 PF00076.22 OAG41659.1 - 1.5e-12 47.1 0.0 2.3e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glyco_hydro_79C PF16862.5 OAG41660.1 - 6.5e-23 81.6 2.0 1.7e-22 80.2 0.3 2.5 3 0 0 3 3 3 1 Glycosyl hydrolase family 79 C-terminal beta domain Zn_clus PF00172.18 OAG41661.1 - 6e-06 26.3 5.0 1.2e-05 25.3 5.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2201 PF09967.9 OAG41661.1 - 0.032 14.4 0.1 0.075 13.2 0.1 1.6 1 0 0 1 1 1 0 VWA-like domain (DUF2201) AMP-binding PF00501.28 OAG41662.1 - 9.4e-92 307.8 0.0 1.2e-91 307.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG41662.1 - 7.8e-14 52.4 0.2 2e-13 51.1 0.2 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DSBA PF01323.20 OAG41663.1 - 4.5e-17 62.5 0.0 5.2e-17 62.2 0.0 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Dpy-30 PF05186.13 OAG41663.1 - 0.16 11.7 0.2 0.29 10.9 0.2 1.5 1 0 0 1 1 1 0 Dpy-30 motif Oxidored_molyb PF00174.19 OAG41664.1 - 1e-45 155.5 0.0 1.5e-45 154.9 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 OAG41664.1 - 5.5e-09 36.2 0.0 1.1e-08 35.2 0.0 1.5 1 1 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Big_7 PF17957.1 OAG41664.1 - 6.4e-05 23.6 0.0 0.00014 22.5 0.0 1.7 1 0 0 1 1 1 1 Bacterial Ig domain Gmad2 PF10648.9 OAG41664.1 - 0.0075 16.5 0.0 0.015 15.5 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin-like domain of bacterial spore germination Y_Y_Y PF07495.13 OAG41664.1 - 0.017 15.1 0.0 0.03 14.3 0.0 1.3 1 0 0 1 1 1 0 Y_Y_Y domain Fungal_trans PF04082.18 OAG41665.1 - 5.9e-11 41.9 0.1 9.9e-11 41.2 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG41665.1 - 3.1e-06 27.2 10.6 5.3e-06 26.5 10.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PEP_mutase PF13714.6 OAG41666.1 - 6e-49 166.7 0.5 6.9e-49 166.4 0.5 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 OAG41666.1 - 4.6e-22 78.2 0.7 6.1e-22 77.8 0.7 1.1 1 0 0 1 1 1 1 Isocitrate lyase family MR_MLE_C PF13378.6 OAG41666.1 - 0.037 13.6 0.4 0.078 12.5 0.3 1.6 1 1 0 1 1 1 0 Enolase C-terminal domain-like Polysacc_deac_1 PF01522.21 OAG41667.1 - 4.3e-21 75.1 0.0 7.2e-21 74.4 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 OAG41667.1 - 1.3e-11 44.6 0.1 3.6e-11 43.1 0.1 1.6 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) Glyco_hydro_57 PF03065.15 OAG41667.1 - 0.0027 17.0 0.0 0.0044 16.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 2-Hacid_dh_C PF02826.19 OAG41668.1 - 2.9e-39 134.3 0.0 6.3e-39 133.2 0.0 1.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 OAG41668.1 - 1e-11 44.7 0.0 1.4e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 OAG41668.1 - 0.019 15.1 0.1 0.041 14.1 0.0 1.6 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase DHDPS PF00701.22 OAG41669.1 - 1.8e-35 122.0 0.0 2.9e-35 121.4 0.0 1.2 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family AAT PF03417.16 OAG41669.1 - 1.1e-25 90.7 0.0 1.9e-25 89.9 0.0 1.5 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Fungal_trans PF04082.18 OAG41669.1 - 4.3e-23 81.7 0.4 2e-22 79.5 0.4 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Aminotran_1_2 PF00155.21 OAG41670.1 - 1.1e-73 248.5 0.0 1.3e-73 248.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Hydantoinase_B PF02538.14 OAG41671.1 - 3.2e-210 698.9 0.3 4.3e-210 698.5 0.3 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 OAG41671.1 - 1.5e-94 316.5 0.0 2.3e-94 315.9 0.0 1.3 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 OAG41671.1 - 7.3e-55 185.4 0.1 4.9e-53 179.5 0.0 2.4 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region MFS_1 PF07690.16 OAG41672.1 - 1.4e-39 136.0 25.0 1.4e-39 136.0 25.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily AMP-binding PF00501.28 OAG41673.1 - 8.3e-79 265.1 0.1 1e-78 264.8 0.1 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG41673.1 - 9e-17 61.8 0.8 2.7e-16 60.3 0.1 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain PIP5K PF01504.18 OAG41674.1 - 2.3e-42 145.1 0.4 3.3e-41 141.3 0.4 2.1 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Oxysterol_BP PF01237.18 OAG41675.1 - 3e-57 194.2 0.0 1.1e-49 169.2 0.0 2.1 1 1 1 2 2 2 2 Oxysterol-binding protein CAP_N PF01213.19 OAG41675.1 - 4.2 6.8 6.6 6.8 6.1 6.6 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Zn_clus PF00172.18 OAG41676.1 - 3.5e-09 36.6 12.5 5.7e-09 36.0 12.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAG41676.1 - 0.00065 18.8 0.3 0.0011 18.1 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF1712 PF08217.11 OAG41677.1 - 5.2e-15 55.0 0.0 1.2e-12 47.1 0.0 2.3 2 0 0 2 2 2 2 Fungal domain of unknown function (DUF1712) Ras PF00071.22 OAG41678.1 - 2.9e-57 192.8 0.0 3.3e-57 192.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAG41678.1 - 3.1e-22 79.0 0.0 4.7e-22 78.5 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAG41678.1 - 2.2e-06 27.2 0.0 3.6e-06 26.6 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 OAG41678.1 - 0.0077 15.7 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit NB-ARC PF00931.22 OAG41678.1 - 0.046 12.9 0.1 0.43 9.7 0.0 2.0 1 1 1 2 2 2 0 NB-ARC domain Gtr1_RagA PF04670.12 OAG41678.1 - 0.14 11.5 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Abhydrolase_6 PF12697.7 OAG41679.1 - 9.4e-17 62.3 0.0 1.2e-16 62.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAG41679.1 - 4.2e-05 23.3 0.0 0.00016 21.4 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold GFRP PF06399.13 OAG41679.1 - 0.03 14.2 0.0 0.084 12.8 0.0 1.7 1 0 0 1 1 1 0 GTP cyclohydrolase I feedback regulatory protein (GFRP) Hydrolase_4 PF12146.8 OAG41679.1 - 0.11 11.8 0.0 0.68 9.2 0.0 2.3 1 1 0 1 1 1 0 Serine aminopeptidase, S33 Zip PF02535.22 OAG41680.1 - 3.1e-44 151.6 0.2 3.5e-43 148.1 0.2 2.0 1 1 0 1 1 1 1 ZIP Zinc transporter E1-E2_ATPase PF00122.20 OAG41681.1 - 2.7e-39 134.5 1.2 4.6e-39 133.8 0.2 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 OAG41681.1 - 5.5e-34 117.5 4.5 5.5e-34 117.5 4.5 2.4 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus HET PF06985.11 OAG41681.1 - 7.3e-29 101.0 1.2 1.4e-28 100.1 1.2 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Hydrolase PF00702.26 OAG41681.1 - 4e-21 76.3 0.0 1.3e-10 42.0 0.2 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 OAG41681.1 - 1.8e-11 44.0 0.0 4.1e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 OAG41681.1 - 1.3e-09 37.6 0.0 3e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.7 OAG41681.1 - 0.0086 16.5 0.0 0.046 14.1 0.0 2.2 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase DUF2231 PF09990.9 OAG41681.1 - 0.19 12.2 2.7 0.37 11.3 0.7 2.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2231) PRA1 PF03208.19 OAG41682.1 - 0.57 9.8 3.5 0.39 10.3 0.1 2.2 1 1 1 2 2 2 0 PRA1 family protein PhoD PF09423.10 OAG41683.1 - 8e-06 25.1 0.1 0.0021 17.1 0.1 2.8 2 1 0 2 2 2 2 PhoD-like phosphatase Rad51 PF08423.11 OAG41684.1 - 2.6e-128 426.7 0.0 3.2e-128 426.4 0.0 1.1 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 OAG41684.1 - 1.4e-10 41.1 0.0 1.8e-10 40.8 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.6 OAG41684.1 - 8.7e-10 38.5 0.0 1.2e-09 38.0 0.0 1.1 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 OAG41684.1 - 9.5e-06 25.1 0.3 2.3e-05 23.9 0.3 1.7 1 1 0 1 1 1 1 KaiC HHH_5 PF14520.6 OAG41684.1 - 2.4e-05 24.8 0.3 8.9e-05 23.0 0.1 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix domain DnaB_C PF03796.15 OAG41684.1 - 0.0088 15.4 0.3 0.081 12.2 0.0 2.0 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain AAA_22 PF13401.6 OAG41684.1 - 0.025 14.9 0.2 0.072 13.4 0.2 1.7 1 1 0 1 1 1 0 AAA domain PAXNEB PF05625.11 OAG41684.1 - 0.061 12.4 2.3 0.36 9.9 0.6 2.1 1 1 1 2 2 2 0 PAXNEB protein AAA_24 PF13479.6 OAG41684.1 - 0.11 12.2 0.0 0.24 11.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain Transferase PF02458.15 OAG41685.1 - 1.9e-25 89.5 0.0 4.7e-22 78.3 0.0 3.0 2 1 0 2 2 2 2 Transferase family PXA PF02194.15 OAG41686.1 - 4.2e-49 167.0 2.6 7.2e-49 166.2 0.6 2.5 2 1 0 2 2 2 1 PXA domain Nexin_C PF08628.12 OAG41686.1 - 9.3e-25 87.4 0.1 3.1e-23 82.5 0.0 2.9 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.24 OAG41686.1 - 1.6e-21 76.4 1.1 4e-21 75.1 0.5 2.1 2 0 0 2 2 2 1 PX domain RGS PF00615.19 OAG41686.1 - 3.6e-12 46.6 0.1 1.4e-11 44.7 0.1 2.1 1 0 0 1 1 1 1 Regulator of G protein signaling domain RRP36 PF06102.12 OAG41686.1 - 0.016 15.2 1.4 0.08 12.9 0.0 2.6 2 0 0 2 2 2 0 rRNA biogenesis protein RRP36 RITA PF17066.5 OAG41686.1 - 0.036 13.7 0.1 0.12 11.9 0.1 1.9 1 0 0 1 1 1 0 RBPJ-interacting and tubulin associated protein HD_assoc PF13286.6 OAG41686.1 - 0.11 13.1 0.4 4.1 8.0 0.0 3.3 1 1 1 2 2 2 0 Phosphohydrolase-associated domain NAD_binding_8 PF13450.6 OAG41687.1 - 5.3e-10 39.4 0.0 1.6e-09 37.9 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.19 OAG41687.1 - 2e-08 33.1 0.1 2.6e-05 22.9 0.0 2.5 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OAG41687.1 - 1.8e-07 30.7 0.1 0.0073 15.6 0.0 3.5 4 1 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG41687.1 - 1.4e-06 27.7 0.0 0.00015 21.0 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 OAG41687.1 - 0.0039 17.2 0.0 0.15 12.0 0.0 2.7 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 OAG41687.1 - 0.068 12.4 0.0 0.87 8.8 0.0 2.4 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Cupin_8 PF13621.6 OAG41688.1 - 3.2e-25 89.3 0.0 3.5e-25 89.2 0.0 1.2 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 OAG41688.1 - 0.001 19.5 0.0 0.0039 17.6 0.0 2.0 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 OAG41688.1 - 0.028 14.1 0.0 0.097 12.4 0.0 1.9 2 0 0 2 2 2 0 Cupin domain Cupin_4 PF08007.12 OAG41688.1 - 0.085 12.3 0.0 0.19 11.1 0.0 1.5 2 0 0 2 2 2 0 Cupin superfamily protein DUF3701 PF12482.8 OAG41688.1 - 0.13 12.4 0.3 0.26 11.4 0.3 1.5 1 0 0 1 1 1 0 Phage integrase protein CK_II_beta PF01214.18 OAG41689.1 - 1e-76 256.8 0.0 2.1e-76 255.8 0.0 1.5 1 1 0 1 1 1 1 Casein kinase II regulatory subunit Spt5_N PF11942.8 OAG41689.1 - 0.00061 20.7 17.7 0.17 12.9 1.7 2.5 2 0 0 2 2 2 2 Spt5 transcription elongation factor, acidic N-terminal PRP38_assoc PF12871.7 OAG41689.1 - 1.9 9.2 23.6 1.2 9.8 10.7 2.5 2 0 0 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Fungal_trans PF04082.18 OAG41690.1 - 1.7e-15 56.8 0.0 2.8e-15 56.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG41690.1 - 0.00018 21.5 8.8 0.00031 20.8 8.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain kleA_kleC PF17383.2 OAG41690.1 - 0.014 15.7 0.0 0.033 14.5 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized KorC regulated protein A Helo_like_N PF17111.5 OAG41690.1 - 0.065 12.6 0.0 2.2 7.6 0.0 2.3 2 0 0 2 2 2 0 Fungal N-terminal domain of STAND proteins bZIP_1 PF00170.21 OAG41691.1 - 0.00019 21.5 5.5 0.00029 20.9 5.5 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 OAG41691.1 - 0.0045 17.0 6.7 0.0069 16.4 6.7 1.2 1 0 0 1 1 1 1 Basic region leucine zipper MAP65_ASE1 PF03999.12 OAG41691.1 - 0.041 12.6 4.1 0.051 12.3 4.1 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) bZIP_Maf PF03131.17 OAG41691.1 - 0.12 12.9 6.7 0.21 12.1 6.7 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor CIA30 PF08547.12 OAG41692.1 - 7.1e-34 117.1 0.3 2.2e-33 115.6 0.3 1.7 1 1 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) DEAD PF00270.29 OAG41694.1 - 1.3e-51 174.8 0.0 2.7e-50 170.6 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAG41694.1 - 5.2e-27 94.4 0.0 2.1e-26 92.4 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG41694.1 - 0.0037 17.3 0.0 0.025 14.6 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HMG_box_2 PF09011.10 OAG41695.1 - 4.5e-16 59.2 9.7 1.6e-12 47.9 0.5 2.8 2 0 0 2 2 2 2 HMG-box domain HMG_box PF00505.19 OAG41695.1 - 9.1e-15 54.8 11.7 4.7e-10 39.7 2.2 3.2 2 1 0 2 2 2 2 HMG (high mobility group) box DUF1702 PF08012.11 OAG41695.1 - 4 6.2 7.3 1.9 7.3 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1702) Ribosomal_L10 PF00466.20 OAG41696.1 - 0.00015 21.8 0.0 0.018 15.1 0.0 2.7 2 1 0 2 2 2 2 Ribosomal protein L10 SSF PF00474.17 OAG41697.1 - 1.9e-17 63.2 32.3 3.5e-17 62.4 32.3 1.4 1 0 0 1 1 1 1 Sodium:solute symporter family Methyltransf_25 PF13649.6 OAG41698.1 - 6.6e-18 65.2 0.0 1.1e-17 64.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG41698.1 - 1.1e-15 58.1 0.0 2.8e-15 56.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAG41698.1 - 1e-11 45.0 0.0 1.4e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG41698.1 - 2.8e-11 43.4 0.0 3.7e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG41698.1 - 6.4e-08 33.2 0.0 1.1e-07 32.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OAG41698.1 - 1.3e-05 24.8 0.0 1.8e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain NodS PF05401.11 OAG41698.1 - 4.4e-05 23.2 0.0 5.3e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) tRNA_U5-meth_tr PF05958.11 OAG41698.1 - 0.00016 20.8 0.0 0.0002 20.5 0.0 1.1 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Ubie_methyltran PF01209.18 OAG41698.1 - 0.00092 18.6 0.0 0.0017 17.7 0.0 1.4 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family CheR PF01739.18 OAG41698.1 - 0.0019 17.7 0.0 0.49 9.9 0.0 2.6 1 1 1 2 2 2 1 CheR methyltransferase, SAM binding domain PrmA PF06325.13 OAG41698.1 - 0.0043 16.5 0.0 0.0059 16.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.9 OAG41698.1 - 0.0081 15.9 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 Lysine methyltransferase FtsJ PF01728.19 OAG41698.1 - 0.0091 16.1 0.0 0.016 15.4 0.0 1.4 1 1 1 2 2 2 1 FtsJ-like methyltransferase CMAS PF02353.20 OAG41698.1 - 0.018 14.3 0.0 0.022 14.1 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase UPF0146 PF03686.13 OAG41698.1 - 0.023 14.6 0.0 0.034 14.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) RrnaAD PF00398.20 OAG41698.1 - 0.028 13.5 0.0 0.035 13.2 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase adh_short PF00106.25 OAG41698.1 - 0.12 11.8 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 short chain dehydrogenase MFS_1 PF07690.16 OAG41699.1 - 2e-23 82.9 41.3 2.4e-21 76.1 33.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG41699.1 - 5.1e-06 25.6 7.7 5.1e-06 25.6 7.7 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter 2OG-FeII_Oxy_3 PF13640.6 OAG41700.1 - 1.3e-09 38.8 0.1 3.2e-09 37.6 0.1 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily adh_short PF00106.25 OAG41701.1 - 1.1e-31 109.8 0.0 3.6e-31 108.1 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG41701.1 - 1.3e-27 96.9 0.0 2.9e-27 95.7 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG41701.1 - 7e-06 26.1 0.1 0.0033 17.4 0.0 2.2 2 0 0 2 2 2 2 KR domain DUF2220 PF09983.9 OAG41701.1 - 0.2 11.0 0.0 0.44 9.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria C-term(DUF2220) adh_short PF00106.25 OAG41702.1 - 4.9e-41 140.3 0.1 6.8e-41 139.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG41702.1 - 3.7e-36 124.8 0.1 5e-36 124.4 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG41702.1 - 6.1e-08 32.8 0.0 1.2e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG41702.1 - 0.0033 16.9 0.0 0.0046 16.4 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family AMP-binding PF00501.28 OAG41703.1 - 3.8e-67 226.7 0.0 4.4e-67 226.5 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG41703.1 - 2e-18 67.1 0.0 5.9e-18 65.6 0.0 1.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain LysR_substrate PF03466.20 OAG41703.1 - 0.082 12.3 0.1 0.16 11.3 0.1 1.4 1 0 0 1 1 1 0 LysR substrate binding domain LRR_4 PF12799.7 OAG41704.1 - 6.4e-10 39.1 15.7 3.1 8.3 0.1 7.6 6 1 1 7 7 7 6 Leucine Rich repeats (2 copies) F-box-like PF12937.7 OAG41704.1 - 4.3e-08 32.9 0.2 1.7e-07 31.0 0.2 2.1 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.6 OAG41704.1 - 6.2e-05 22.7 28.5 3.2 8.0 0.1 10.7 12 0 0 12 12 12 3 Leucine Rich repeat F-box PF00646.33 OAG41704.1 - 6.6e-05 22.7 0.1 6.6e-05 22.7 0.1 2.4 2 0 0 2 2 2 1 F-box domain LRR_1 PF00560.33 OAG41704.1 - 3.4 8.6 15.7 1.7e+02 3.4 0.1 8.0 8 1 0 8 8 8 0 Leucine Rich Repeat Glyco_hydro_15 PF00723.21 OAG41706.1 - 0.19 10.5 0.3 0.3 9.8 0.3 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 15 MFS_1 PF07690.16 OAG41707.1 - 4.1e-20 72.0 52.8 5.2e-19 68.4 29.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4674 PF15719.5 OAG41709.1 - 1.6 8.8 4.0 2.5 8.1 4.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4674) Ribosomal_L1 PF00687.21 OAG41710.1 - 6.7e-47 159.9 0.3 7.5e-47 159.7 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Acetyltransf_1 PF00583.25 OAG41711.1 - 7.3e-12 45.6 0.0 1.1e-11 45.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OAG41711.1 - 2.4e-11 43.9 0.0 3.3e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OAG41711.1 - 1.5e-09 37.9 0.0 4e-09 36.5 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAG41711.1 - 2.1e-09 37.2 0.0 4.8e-09 36.1 0.0 1.6 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 OAG41711.1 - 1.1e-06 28.6 0.0 2.7e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.7 OAG41711.1 - 0.00054 20.7 0.0 0.00072 20.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 OAG41711.1 - 0.16 12.1 0.0 0.41 10.7 0.0 1.8 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain Arf PF00025.21 OAG41712.1 - 6.6e-80 266.7 0.1 7.7e-80 266.4 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 OAG41712.1 - 3e-14 53.2 0.0 4.3e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 OAG41712.1 - 5.1e-14 52.1 0.0 6.2e-14 51.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 OAG41712.1 - 2.5e-13 49.9 1.4 2e-09 37.1 0.3 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 OAG41712.1 - 8.2e-13 48.3 0.0 8.9e-13 48.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 OAG41712.1 - 1.7e-10 40.7 0.0 2.1e-10 40.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OAG41712.1 - 4.1e-06 26.8 0.0 6.4e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 OAG41712.1 - 0.011 15.1 0.7 0.026 13.8 0.7 1.7 1 1 0 1 1 1 0 6-phosphofructo-2-kinase SPRY PF00622.28 OAG41713.1 - 6.3e-07 29.5 0.0 1.9e-06 28.0 0.0 1.8 2 0 0 2 2 2 1 SPRY domain Glyco_hydro_3_C PF01915.22 OAG41714.1 - 4.1e-35 121.6 0.1 9.4e-35 120.4 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 OAG41714.1 - 1.6e-34 119.8 0.0 2.4e-34 119.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 OAG41714.1 - 1.8e-06 27.9 0.0 4.1e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain Sugar_tr PF00083.24 OAG41715.1 - 4.1e-117 391.8 22.8 7.5e-117 390.9 22.8 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG41715.1 - 7.1e-21 74.5 44.8 3.2e-16 59.2 13.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Mersacidin PF16934.5 OAG41715.1 - 0.095 12.5 0.7 0.27 11.0 0.0 2.1 2 0 0 2 2 2 0 Two-component Enterococcus faecalis cytolysin (EFC) DUF4776 PF16003.5 OAG41716.1 - 0.078 12.0 0.2 0.13 11.3 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) Abhydrolase_3 PF07859.13 OAG41719.1 - 4.2e-39 134.6 0.0 1.4e-37 129.6 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 OAG41719.1 - 1.3e-05 24.3 0.1 3e-05 23.1 0.1 1.5 1 1 0 1 1 1 1 Carboxylesterase family adh_short_C2 PF13561.6 OAG41720.1 - 4.4e-47 160.6 3.0 6e-47 160.2 3.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG41720.1 - 1.9e-41 141.7 1.0 1.9e-41 141.7 1.0 1.3 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 OAG41720.1 - 1.2e-10 41.6 0.3 1.9e-10 41.0 0.3 1.2 1 0 0 1 1 1 1 KR domain DUF429 PF04250.13 OAG41720.1 - 0.023 14.5 0.0 0.035 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF429) Glyco_hydro_88 PF07470.13 OAG41721.1 - 1.5e-82 277.5 0.8 2.3e-82 276.9 0.8 1.2 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 p450 PF00067.22 OAG41721.1 - 1.4e-69 235.1 0.0 1.9e-69 234.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_127 PF07944.12 OAG41721.1 - 0.021 13.4 0.1 0.042 12.4 0.1 1.4 1 0 0 1 1 1 0 Beta-L-arabinofuranosidase, GH127 DUF3915 PF13054.6 OAG41721.1 - 0.044 13.8 0.5 0.087 12.8 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) MFS_1 PF07690.16 OAG41722.1 - 3.8e-35 121.5 18.9 3.8e-35 121.5 18.9 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily EphA2_TM PF14575.6 OAG41722.1 - 0.4 11.6 1.2 31 5.5 0.0 3.6 3 1 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Myb_DNA-binding PF00249.31 OAG41725.1 - 1e-15 57.7 3.3 1.2e-08 35.0 0.5 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OAG41725.1 - 7.1e-11 42.2 1.9 8.7e-06 25.9 0.2 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OAG41725.1 - 0.05 13.5 0.6 0.082 12.8 0.6 1.5 1 1 0 1 1 1 0 Myb DNA-binding like HTH_32 PF13565.6 OAG41725.1 - 0.31 11.7 0.1 0.31 11.7 0.1 1.9 3 0 0 3 3 3 0 Homeodomain-like domain AMP-binding PF00501.28 OAG41726.1 - 1.2e-69 235.0 0.0 2e-69 234.2 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG41726.1 - 1e-10 42.4 0.1 2.3e-10 41.3 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain bZIP_1 PF00170.21 OAG41727.1 - 2.8e-08 33.7 12.4 5e-08 32.9 12.4 1.4 1 1 0 1 1 1 1 bZIP transcription factor DUF2310 PF10071.9 OAG41727.1 - 0.0086 15.4 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 1 Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310) bZIP_2 PF07716.15 OAG41727.1 - 0.019 15.0 13.4 0.08 13.0 13.4 1.8 1 1 0 1 1 1 0 Basic region leucine zipper TSC22 PF01166.18 OAG41727.1 - 0.022 15.1 0.7 0.035 14.4 0.7 1.4 1 0 0 1 1 1 0 TSC-22/dip/bun family Herpes_UL6 PF01763.16 OAG41727.1 - 0.023 13.2 0.8 0.026 13.0 0.8 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like bZIP_Maf PF03131.17 OAG41727.1 - 0.033 14.7 9.2 0.051 14.1 9.2 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor DUF5094 PF17015.5 OAG41727.1 - 0.098 12.8 0.4 0.13 12.4 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5094) Jnk-SapK_ap_N PF09744.9 OAG41727.1 - 0.29 11.3 6.4 0.41 10.9 6.4 1.1 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 IATP PF04568.12 OAG41727.1 - 0.39 11.2 3.5 0.72 10.3 3.5 1.6 1 1 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP Fungal_trans PF04082.18 OAG41728.1 - 4.9e-21 74.9 0.0 6.9e-20 71.2 0.0 2.3 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG41728.1 - 3.3e-06 27.1 12.9 5.4e-06 26.4 12.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Slx4 PF09494.10 OAG41729.1 - 1.6e-13 50.4 0.0 3.9e-13 49.1 0.0 1.6 1 0 0 1 1 1 1 Slx4 endonuclease Hist_deacetyl PF00850.19 OAG41730.1 - 8.9e-56 189.6 0.0 1.6e-55 188.8 0.0 1.4 1 0 0 1 1 1 1 Histone deacetylase domain Clr5 PF14420.6 OAG41730.1 - 8.9e-15 54.7 4.9 1.9e-14 53.6 3.6 2.2 2 0 0 2 2 2 1 Clr5 domain HTH_33 PF13592.6 OAG41730.1 - 0.03 14.0 0.0 0.064 12.9 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn helix Bax1-I PF01027.20 OAG41731.1 - 2e-32 112.7 9.5 3.1e-32 112.1 9.5 1.2 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 MFS_1 PF07690.16 OAG41732.1 - 1.1e-33 116.7 28.1 1.5e-33 116.2 28.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Cu-oxidase_3 PF07732.15 OAG41733.1 - 1.6e-25 89.4 0.0 4.7e-25 87.9 0.0 1.8 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase PF00394.22 OAG41733.1 - 7.1e-24 84.7 0.0 1.4e-23 83.8 0.0 1.4 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 OAG41733.1 - 7.4e-17 61.4 2.6 3.1e-13 49.6 2.4 3.4 3 1 0 3 3 3 2 Multicopper oxidase Ceramidse_alk_C PF17048.5 OAG41733.1 - 0.043 13.7 0.0 0.17 11.8 0.0 1.9 2 0 0 2 2 2 0 Neutral/alkaline non-lysosomal ceramidase, C-terminal Oxidored_FMN PF00724.20 OAG41734.1 - 2.9e-59 201.0 0.0 7e-57 193.2 0.0 2.4 1 1 1 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family adh_short PF00106.25 OAG41735.1 - 7.6e-36 123.4 0.4 9.6e-36 123.1 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG41735.1 - 2.4e-29 102.5 0.1 3e-29 102.3 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 OAG41735.1 - 8.6e-07 28.7 0.3 1.5e-06 27.8 0.3 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 OAG41735.1 - 4.9e-05 23.3 0.6 8.7e-05 22.5 0.6 1.5 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 OAG41735.1 - 0.0024 17.8 0.2 0.003 17.5 0.2 1.4 1 1 0 1 1 1 1 NAD(P)H-binding Viral_protease PF08715.10 OAG41735.1 - 0.032 13.6 0.0 0.041 13.2 0.0 1.2 1 0 0 1 1 1 0 Papain like viral protease FtsJ PF01728.19 OAG41735.1 - 0.087 12.9 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase NmrA PF05368.13 OAG41735.1 - 0.088 12.4 0.2 0.17 11.4 0.1 1.5 2 0 0 2 2 2 0 NmrA-like family PBP_like PF12727.7 OAG41735.1 - 0.12 11.5 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 PBP superfamily domain DUF3405 PF11885.8 OAG41736.1 - 4.7e-161 536.9 3.4 7.4e-147 490.1 0.9 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3405) CGI-121 PF08617.10 OAG41737.1 - 4.3e-53 179.8 0.0 5.7e-53 179.4 0.0 1.2 1 0 0 1 1 1 1 Kinase binding protein CGI-121 LYRIC PF15686.5 OAG41738.1 - 0.059 12.9 0.6 0.086 12.4 0.6 1.1 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family YuiB PF14068.6 OAG41738.1 - 0.084 13.5 0.0 0.084 13.5 0.0 2.2 3 1 0 3 3 3 0 Putative membrane protein Tetraspanin PF00335.20 OAG41738.1 - 0.14 11.9 7.2 0.57 9.8 7.3 1.9 1 1 0 1 1 1 0 Tetraspanin family Prenyltrans PF00432.21 OAG41738.1 - 0.17 11.7 1.1 0.52 10.1 0.1 2.3 2 0 0 2 2 2 0 Prenyltransferase and squalene oxidase repeat Myco_arth_vir_N PF09610.10 OAG41738.1 - 1.4 9.0 9.5 2 8.5 1.0 2.6 2 0 0 2 2 2 0 Mycoplasma virulence signal region (Myco_arth_vir_N) DUF4131 PF13567.6 OAG41738.1 - 1.7 8.3 7.4 0.18 11.4 2.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Yip1 PF04893.17 OAG41738.1 - 3.2 7.4 15.9 2.4e+02 1.4 15.9 2.6 1 1 0 1 1 1 0 Yip1 domain RNA_pol_Rpb1_5 PF04998.17 OAG41739.1 - 1.3e-101 339.5 0.2 1.9e-101 339.0 0.2 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.12 OAG41739.1 - 9.6e-97 324.1 0.0 1.4e-96 323.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 OAG41739.1 - 8.7e-77 257.0 0.0 1.5e-76 256.3 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 OAG41739.1 - 5.3e-57 192.7 0.3 9.1e-57 192.0 0.3 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.18 OAG41739.1 - 1.7e-44 151.5 0.0 3.4e-44 150.5 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.12 OAG41739.1 - 1.2e-40 138.6 1.9 2.6e-40 137.5 1.9 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.17 OAG41739.1 - 1.7e-34 118.0 0.2 4.1e-34 116.8 0.2 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.13 OAG41739.1 - 1.3e-12 47.3 233.2 0.0092 16.3 10.4 16.8 7 5 10 19 19 19 16 RNA polymerase Rpb1 C-terminal repeat WD40 PF00400.32 OAG41740.1 - 6.1e-13 49.0 8.0 7.8e-05 23.4 0.4 5.3 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG41740.1 - 5.9e-12 45.7 0.2 0.043 14.1 0.0 4.5 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 OAG41740.1 - 0.0003 19.4 0.0 0.00051 18.7 0.0 1.4 1 0 0 1 1 1 1 Cytochrome D1 heme domain CTNNBL PF08216.11 OAG41741.1 - 1.9e-37 127.6 0.5 7.8e-37 125.6 0.0 2.3 2 0 0 2 2 2 1 Catenin-beta-like, Arm-motif containing nuclear Crl PF07417.12 OAG41741.1 - 0.022 14.8 0.1 6.6 6.8 0.0 2.7 2 0 0 2 2 2 0 Sigma factor-binding transcriptional regulator Crl RNA_pol_Rpb2_6 PF00562.28 OAG41742.1 - 9.5e-123 410.1 0.4 1.6e-122 409.4 0.4 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 OAG41742.1 - 2.5e-50 170.8 0.0 5.3e-50 169.7 0.0 1.6 1 1 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 OAG41742.1 - 4.2e-35 121.1 0.0 9e-35 120.0 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 OAG41742.1 - 1.7e-33 114.9 0.5 4.6e-33 113.5 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 OAG41742.1 - 1.1e-24 86.4 0.1 2.4e-24 85.3 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 OAG41742.1 - 1.2e-19 70.6 0.4 3.7e-19 69.0 0.4 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RNA_pol_Rpb2_4 PF04566.13 OAG41742.1 - 1.3e-18 67.1 1.2 2.8e-18 66.0 0.2 2.2 3 0 0 3 3 3 1 RNA polymerase Rpb2, domain 4 MRNIP PF15749.5 OAG41742.1 - 0.00081 20.1 0.3 0.0017 19.0 0.3 1.5 1 0 0 1 1 1 1 MRN-interacting protein Macoilin PF09726.9 OAG41744.1 - 6.4 5.2 8.7 6.5 5.2 8.7 1.1 1 0 0 1 1 1 0 Macoilin family Apt1 PF10351.9 OAG41744.1 - 7.3 5.3 9.5 8.7 5.1 9.5 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SBDS_C PF09377.10 OAG41745.1 - 5.4e-43 145.7 0.0 1.1e-42 144.7 0.0 1.5 2 0 0 2 2 2 1 SBDS protein C-terminal domain SBDS PF01172.18 OAG41745.1 - 7.6e-35 118.9 0.2 1.3e-34 118.1 0.2 1.4 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein RNB PF00773.19 OAG41746.1 - 2e-24 86.6 0.2 9.5e-19 67.9 0.0 2.3 2 0 0 2 2 2 2 RNB domain Phage_TAC_7 PF10109.9 OAG41746.1 - 0.048 13.8 0.0 0.13 12.4 0.0 1.7 1 0 0 1 1 1 0 Phage tail assembly chaperone proteins, E, or 41 or 14 Amidase PF01425.21 OAG41747.1 - 2.9e-84 283.6 0.0 4.2e-84 283.1 0.0 1.2 1 0 0 1 1 1 1 Amidase TRP PF06011.12 OAG41749.1 - 2.8e-38 131.8 18.1 3.2e-37 128.3 18.2 2.0 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 OAG41749.1 - 4.8e-22 78.8 0.1 7.6e-22 78.2 0.1 1.3 1 0 0 1 1 1 1 ML-like domain DUF1772 PF08592.11 OAG41749.1 - 2.4 8.5 7.1 14 6.0 0.2 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) Zn_clus PF00172.18 OAG41750.1 - 2.4e-05 24.4 12.9 4.1e-05 23.6 12.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAG41750.1 - 0.0066 15.5 0.4 0.014 14.4 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Antimicrobial25 PF16839.5 OAG41750.1 - 0.94 9.6 7.5 2.5 8.3 7.5 1.6 1 0 0 1 1 1 0 Nematode antimicrobial peptide Nucleopor_Nup85 PF07575.13 OAG41751.1 - 1.5e-21 76.7 0.0 6.3e-15 54.8 0.0 2.6 3 0 0 3 3 3 2 Nup85 Nucleoporin ADH_N PF08240.12 OAG41752.1 - 2e-22 79.1 1.7 3.8e-22 78.2 1.7 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG41752.1 - 1.9e-19 70.0 0.0 3.1e-19 69.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAG41752.1 - 7.4e-11 43.2 0.0 1.1e-10 42.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 OAG41752.1 - 0.081 12.3 0.3 0.16 11.4 0.1 1.5 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADIP PF11559.8 OAG41753.1 - 5e-25 88.4 16.0 5e-25 88.4 16.0 1.8 2 0 0 2 2 2 1 Afadin- and alpha -actinin-Binding GrpE PF01025.19 OAG41753.1 - 0.094 12.4 4.0 0.62 9.7 3.6 2.4 2 0 0 2 2 2 0 GrpE DUF3135 PF11333.8 OAG41753.1 - 0.31 11.3 3.1 14 6.1 0.3 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3135) Golgin_A5 PF09787.9 OAG41753.1 - 1.8 8.0 15.4 0.65 9.4 11.9 2.0 1 1 0 1 1 1 0 Golgin subfamily A member 5 F-box PF00646.33 OAG41754.1 - 2.9e-08 33.4 2.7 8.8e-08 31.9 2.7 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 OAG41754.1 - 0.00015 21.6 0.5 0.00047 20.0 0.5 1.9 1 0 0 1 1 1 1 F-box-like TPR_9 PF13371.6 OAG41754.1 - 0.00061 19.9 0.0 0.0023 18.1 0.0 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 OAG41754.1 - 0.0027 18.4 2.6 0.077 13.9 0.2 3.9 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 OAG41754.1 - 0.007 17.0 1.2 0.48 11.1 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 OAG41754.1 - 0.0084 16.2 1.3 7.5 6.9 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat F-box_4 PF15966.5 OAG41754.1 - 0.016 15.1 0.1 0.036 14.0 0.1 1.5 1 0 0 1 1 1 0 F-box COX5A PF02284.16 OAG41754.1 - 0.018 15.1 0.7 0.049 13.6 0.1 2.0 2 0 0 2 2 2 0 Cytochrome c oxidase subunit Va NYD-SP12_N PF15015.6 OAG41754.1 - 0.092 11.1 0.1 0.14 10.5 0.1 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated, N-terminal TPR_1 PF00515.28 OAG41754.1 - 0.16 11.8 0.5 3.4 7.7 0.1 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF1349 PF07081.11 OAG41755.1 - 7.3e-20 71.4 0.0 9.9e-20 71.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) SRP_TPR_like PF17004.5 OAG41756.1 - 8.8e-19 67.6 0.8 2e-18 66.5 0.8 1.6 1 0 0 1 1 1 1 Putative TPR-like repeat SRP72 PF08492.12 OAG41756.1 - 5.5e-16 58.7 6.7 5.5e-16 58.7 6.7 2.3 2 0 0 2 2 2 1 SRP72 RNA-binding domain TPR_19 PF14559.6 OAG41756.1 - 2e-07 31.4 7.6 0.09 13.3 0.0 6.1 5 2 2 7 7 7 2 Tetratricopeptide repeat TPR_4 PF07721.14 OAG41756.1 - 9.2e-05 22.7 0.3 23 6.0 0.2 5.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 OAG41756.1 - 0.00058 19.6 2.1 15 5.6 0.3 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 OAG41756.1 - 0.00074 20.1 8.9 3.2 8.8 0.0 6.3 7 0 0 7 7 7 1 Tetratricopeptide repeat ANAPC3 PF12895.7 OAG41756.1 - 0.00075 19.7 3.6 1.5 9.1 0.3 4.6 5 0 0 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 OAG41756.1 - 0.0084 16.1 0.2 4.8 7.4 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 OAG41756.1 - 0.043 13.9 14.5 4.7 7.6 0.4 5.7 7 0 0 7 7 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 OAG41756.1 - 0.051 14.2 5.1 51 4.8 0.0 4.8 5 0 0 5 5 4 0 Tetratricopeptide repeat PPR PF01535.20 OAG41756.1 - 0.061 13.6 0.1 3.9 8.0 0.0 3.8 4 0 0 4 4 3 0 PPR repeat TPR_20 PF14561.6 OAG41756.1 - 0.14 12.5 3.3 0.94 9.9 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 OAG41756.1 - 0.46 11.2 13.6 3.9 8.2 0.0 4.6 4 2 1 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 OAG41756.1 - 0.54 10.2 4.0 40 4.3 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 OAG41756.1 - 0.62 10.4 7.5 33 5.0 0.0 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat CAF1 PF04857.20 OAG41757.1 - 7.4e-60 202.8 0.0 9.3e-43 146.6 0.0 2.2 1 1 1 2 2 2 2 CAF1 family ribonuclease DNA_pol_A_exo1 PF01612.20 OAG41757.1 - 0.0047 16.6 0.0 0.048 13.4 0.0 2.3 2 0 0 2 2 2 1 3'-5' exonuclease DUF2312 PF10073.9 OAG41758.1 - 0.091 12.4 0.1 0.3 10.8 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) Dimerisation PF08100.11 OAG41758.1 - 0.17 11.9 0.6 4.8 7.3 0.2 3.0 3 0 0 3 3 3 0 Dimerisation domain COG5 PF10392.9 OAG41758.1 - 0.36 11.0 5.5 0.1 12.8 0.7 2.4 3 0 0 3 3 3 0 Golgi transport complex subunit 5 CAP_N PF01213.19 OAG41758.1 - 0.37 10.2 7.1 1.1 8.7 7.1 1.8 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Sacchrp_dh_NADP PF03435.18 OAG41759.1 - 8.1e-19 68.2 0.0 1.5e-18 67.3 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 OAG41759.1 - 0.00085 19.8 0.0 0.0016 18.9 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 OAG41759.1 - 0.03 14.4 0.1 0.075 13.1 0.0 1.6 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DapB_N PF01113.20 OAG41759.1 - 0.06 13.5 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus zf-RING_2 PF13639.6 OAG41760.1 - 1.9e-08 34.5 2.0 1.9e-08 34.5 2.0 3.7 3 1 0 3 3 3 1 Ring finger domain PHD PF00628.29 OAG41760.1 - 2.9e-08 33.5 10.3 2.9e-08 33.5 10.3 2.7 2 1 0 2 2 2 1 PHD-finger zf-rbx1 PF12678.7 OAG41760.1 - 3.8e-07 30.3 8.3 9.1e-07 29.1 1.3 2.6 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 OAG41760.1 - 2.8e-05 23.9 2.1 2.8e-05 23.9 2.1 3.3 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAG41760.1 - 3.4e-05 23.7 0.4 3.4e-05 23.7 0.4 3.2 3 1 0 3 3 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 OAG41760.1 - 9.4e-05 22.2 2.0 9.4e-05 22.2 2.0 3.1 2 1 1 3 3 3 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 OAG41760.1 - 0.00029 20.6 0.9 0.00029 20.6 0.9 3.0 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OAG41760.1 - 0.00065 19.5 0.9 0.00065 19.5 0.9 3.6 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 OAG41760.1 - 0.0059 16.6 0.1 0.0059 16.6 0.1 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger C1_2 PF03107.16 OAG41760.1 - 0.012 16.0 1.7 0.012 16.0 1.7 3.1 4 0 0 4 4 4 0 C1 domain zinc_ribbon_4 PF13717.6 OAG41760.1 - 0.044 13.7 1.3 2.1 8.4 0.1 3.3 3 0 0 3 3 3 0 zinc-ribbon domain PHD_2 PF13831.6 OAG41760.1 - 0.065 12.8 5.8 0.18 11.4 5.8 1.8 1 0 0 1 1 1 0 PHD-finger Rtf2 PF04641.12 OAG41760.1 - 0.21 10.9 1.9 3.4 7.0 0.0 2.3 2 0 0 2 2 2 0 Rtf2 RING-finger zf-PHD-like PF15446.6 OAG41760.1 - 0.26 10.9 5.4 0.1 12.2 1.8 2.1 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain DZR PF12773.7 OAG41760.1 - 0.36 10.9 8.4 47 4.1 8.4 2.8 1 1 0 1 1 1 0 Double zinc ribbon Zn_ribbon_17 PF17120.5 OAG41760.1 - 0.74 9.5 11.8 0.16 11.6 1.2 2.4 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 OAG41760.1 - 1.7 8.8 14.8 0.058 13.4 1.9 3.3 2 2 1 3 3 3 0 RING-type zinc-finger CDC37_M PF08565.11 OAG41762.1 - 9.2e-05 22.3 0.0 0.00023 21.1 0.0 1.6 1 1 0 1 1 1 1 Cdc37 Hsp90 binding domain DUF4482 PF14818.6 OAG41763.1 - 0.034 15.0 2.0 0.084 13.7 2.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4482) PBP-Tp47_a PF14889.6 OAG41763.1 - 0.071 12.7 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Penicillin-binding protein Tp47 domain a CHIP_TPR_N PF18391.1 OAG41763.1 - 0.26 12.1 2.7 0.81 10.5 2.7 1.9 1 0 0 1 1 1 0 CHIP N-terminal tetratricopeptide repeat domain ssDNA_DBD PF18333.1 OAG41763.1 - 2 8.5 6.5 0.25 11.5 0.6 2.4 3 0 0 3 3 3 0 Non-canonical single-stranded DNA-binding domain zf-C4H2 PF10146.9 OAG41763.1 - 5.5 7.2 6.2 4.3 7.6 3.5 2.1 1 1 1 2 2 2 0 Zinc finger-containing protein DJ-1_PfpI PF01965.24 OAG41766.1 - 3.8e-07 30.1 0.0 4.6e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family zf-C2H2_7 PF15269.6 OAG41767.1 - 0.12 12.5 0.9 0.21 11.7 0.9 1.3 1 0 0 1 1 1 0 Zinc-finger IDO PF01231.18 OAG41768.1 - 3.9e-36 124.8 0.0 5.5e-36 124.3 0.0 1.2 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase Endotoxin_N PF03945.14 OAG41768.1 - 0.074 12.7 0.1 0.58 9.8 0.0 2.0 2 0 0 2 2 2 0 delta endotoxin, N-terminal domain HET PF06985.11 OAG41769.1 - 1.6e-26 93.4 0.0 4.8e-26 91.9 0.0 1.8 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.16 OAG41770.1 - 1.1e-33 116.6 43.2 1.1e-33 116.6 43.2 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG41770.1 - 3.1e-10 39.5 40.7 6.7e-06 25.2 16.0 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter Pkinase PF00069.25 OAG41771.1 - 2.9e-75 253.1 0.0 4.6e-75 252.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG41771.1 - 5.1e-36 124.3 0.0 1.2e-35 123.0 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAG41771.1 - 1.1e-05 24.9 1.5 0.43 9.8 0.0 3.2 3 0 0 3 3 3 3 Kinase-like APH PF01636.23 OAG41771.1 - 0.0033 17.4 0.0 0.3 11.0 0.0 2.9 2 1 1 3 3 3 2 Phosphotransferase enzyme family DUF3501 PF12007.8 OAG41771.1 - 0.039 13.9 0.1 0.074 13.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3501) Pkinase_fungal PF17667.1 OAG41771.1 - 0.066 12.0 0.5 0.24 10.2 0.0 2.0 3 0 0 3 3 3 0 Fungal protein kinase PBP1_TM PF14812.6 OAG41771.1 - 1.1 9.7 3.9 2.3 8.6 1.8 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RasGAP_C PF03836.15 OAG41773.1 - 2.2e-48 163.9 5.1 2.2e-48 163.9 5.1 3.5 3 0 0 3 3 3 1 RasGAP C-terminus RasGAP PF00616.19 OAG41773.1 - 6.2e-48 163.3 0.5 8.4e-47 159.6 0.0 2.7 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase CH PF00307.31 OAG41773.1 - 8.8e-13 48.4 0.1 4.1e-12 46.2 0.0 2.2 2 0 0 2 2 2 1 Calponin homology (CH) domain IQ PF00612.27 OAG41773.1 - 1.1e-09 37.2 53.4 0.15 12.0 0.0 14.7 16 0 0 16 16 16 7 IQ calmodulin-binding motif CAMSAP_CH PF11971.8 OAG41773.1 - 0.0018 18.0 0.0 0.0069 16.2 0.0 2.0 2 0 0 2 2 2 1 CAMSAP CH domain Ead_Ea22 PF13935.6 OAG41773.1 - 0.34 11.6 6.8 7.7 7.2 1.0 2.9 2 0 0 2 2 2 0 Ead/Ea22-like protein IMPDH PF00478.25 OAG41774.1 - 2.5e-129 431.2 2.7 2.9e-129 431.0 2.7 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 OAG41774.1 - 4.3e-19 68.7 0.0 6.9e-10 39.2 0.0 2.6 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.18 OAG41774.1 - 3.5e-07 29.6 0.7 1.4e-06 27.6 0.6 1.9 2 0 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.15 OAG41774.1 - 1.4e-06 28.0 6.4 0.013 14.9 6.1 2.7 2 1 1 3 3 3 2 Nitronate monooxygenase His_biosynth PF00977.21 OAG41774.1 - 7.8e-05 22.2 1.9 0.00021 20.9 1.9 1.6 1 1 0 1 1 1 1 Histidine biosynthesis protein YpsA PF06908.11 OAG41774.1 - 0.0045 17.0 0.0 0.0081 16.2 0.0 1.3 1 0 0 1 1 1 1 YspA SLOG family PK PF00224.21 OAG41774.1 - 0.022 13.7 0.0 0.037 12.9 0.0 1.3 1 0 0 1 1 1 0 Pyruvate kinase, barrel domain ThiG PF05690.14 OAG41774.1 - 0.06 12.7 2.1 0.097 12.0 1.1 1.8 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG Aldolase PF01081.19 OAG41774.1 - 0.063 12.7 0.4 0.31 10.4 0.1 2.1 1 1 0 2 2 2 0 KDPG and KHG aldolase NUDIX PF00293.28 OAG41775.1 - 9.9e-08 32.1 0.0 2.7e-06 27.4 0.0 2.4 1 1 0 2 2 2 1 NUDIX domain Ssu72 PF04722.13 OAG41776.1 - 3.2e-81 271.5 0.0 3.8e-81 271.2 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein SH3_1 PF00018.28 OAG41777.1 - 2.7e-11 42.9 0.0 4.6e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 OAG41777.1 - 3.5e-09 36.4 0.6 5.7e-09 35.7 0.0 1.7 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 OAG41777.1 - 4.2e-07 29.5 0.0 7.7e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Pmp3 PF01679.17 OAG41778.1 - 9.3e-12 45.0 5.0 1.7e-11 44.1 5.0 1.5 1 0 0 1 1 1 1 Proteolipid membrane potential modulator ATP12 PF07542.11 OAG41779.1 - 2.3e-44 150.6 0.2 3.8e-44 149.9 0.2 1.4 1 0 0 1 1 1 1 ATP12 chaperone protein Acyl-CoA_dh_1 PF00441.24 OAG41780.1 - 4.6e-33 114.5 0.1 6.1e-33 114.1 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 OAG41780.1 - 4.2e-23 81.4 0.1 8.6e-23 80.4 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 OAG41780.1 - 5.4e-17 62.5 0.0 2.7e-16 60.2 0.0 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 OAG41780.1 - 2.9e-06 27.6 0.0 4.8e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain adh_short PF00106.25 OAG41781.1 - 1.6e-80 269.2 11.2 1.2e-44 152.1 2.7 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAG41781.1 - 1.5e-61 207.9 7.6 1.6e-33 116.2 1.6 2.5 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG41781.1 - 6.9e-26 91.3 7.4 4.9e-13 49.4 0.6 2.9 2 1 0 2 2 2 2 KR domain THF_DHG_CYH_C PF02882.19 OAG41781.1 - 0.031 13.6 1.9 0.35 10.2 0.1 2.5 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.18 OAG41781.1 - 0.9 9.4 3.8 2.1 8.2 0.1 2.4 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AMP-binding PF00501.28 OAG41782.1 - 4.4e-86 289.1 0.0 5.7e-86 288.7 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG41782.1 - 1.5e-15 57.9 0.1 6.4e-15 55.9 0.0 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DUF4817 PF16087.5 OAG41782.1 - 0.12 12.3 0.0 0.41 10.5 0.0 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain (DUF4817) Sugar_tr PF00083.24 OAG41783.1 - 2.7e-71 240.8 19.1 3.2e-71 240.5 19.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG41783.1 - 1.4e-19 70.2 30.3 1.4e-19 70.2 30.3 1.8 1 1 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.6 OAG41783.1 - 7.9e-06 24.7 6.5 7.9e-06 24.7 6.5 2.5 3 0 0 3 3 3 1 MFS/sugar transport protein DUF3099 PF11298.8 OAG41783.1 - 0.014 15.5 1.1 0.21 11.8 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3099) AMP-binding PF00501.28 OAG41784.1 - 1.8e-67 227.8 0.0 2.3e-67 227.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG41784.1 - 5.1e-05 24.2 0.0 0.00013 22.9 0.0 1.7 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Fungal_trans PF04082.18 OAG41785.1 - 1.1e-22 80.4 0.1 1.6e-22 79.8 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG41785.1 - 8.2e-07 29.0 7.5 1.9e-06 27.9 7.5 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 4HBT_3 PF13622.6 OAG41786.1 - 1.3e-65 222.1 7.5 1.6e-65 221.8 7.5 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 OAG41786.1 - 2.3e-24 85.7 0.1 8.4e-12 45.1 0.0 4.3 3 1 0 3 3 3 3 Acyl-CoA thioesterase 4HBT PF03061.22 OAG41786.1 - 0.037 14.4 0.3 1.3 9.4 0.2 2.4 2 0 0 2 2 2 0 Thioesterase superfamily Thiolase_C PF02803.18 OAG41787.1 - 4.3e-12 45.8 0.3 2.4e-10 40.1 0.0 2.4 1 1 1 2 2 2 1 Thiolase, C-terminal domain Thiolase_N PF00108.23 OAG41787.1 - 2e-10 40.5 0.1 4e-07 29.7 0.0 3.3 3 1 0 3 3 3 2 Thiolase, N-terminal domain ACP_syn_III PF08545.10 OAG41787.1 - 3.1e-06 26.9 0.1 0.0002 21.1 0.1 2.5 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.26 OAG41787.1 - 0.00022 20.9 0.1 0.00066 19.3 0.0 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 OAG41787.1 - 0.058 13.4 0.1 0.45 10.5 0.0 2.3 2 0 0 2 2 2 0 Beta-ketoacyl synthase, C-terminal domain RRP7 PF12923.7 OAG41789.1 - 2.5e-29 101.8 12.2 2.5e-29 101.8 12.2 1.6 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain RRM_Rrp7 PF17799.1 OAG41789.1 - 2.7e-25 89.1 0.0 7.1e-25 87.7 0.0 1.7 2 0 0 2 2 2 1 Rrp7 RRM-like N-terminal domain DUF5093 PF17011.5 OAG41789.1 - 0.0096 16.2 2.5 0.01 16.2 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF5093) FoP_duplication PF13865.6 OAG41789.1 - 0.62 10.6 0.0 0.62 10.6 0.0 3.0 2 1 1 3 3 3 0 C-terminal duplication domain of Friend of PRMT1 HET PF06985.11 OAG41790.1 - 5e-27 95.1 0.0 9.2e-26 90.9 0.0 2.8 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Fungal_trans PF04082.18 OAG41792.1 - 1.1e-06 27.9 0.2 1.9e-06 27.1 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG41792.1 - 6.6 6.9 19.5 0.073 13.2 4.8 2.8 3 0 0 3 3 3 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Transp_cyt_pur PF02133.15 OAG41793.1 - 3.3e-48 164.6 28.3 4.1e-48 164.3 28.3 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF3087 PF11286.8 OAG41793.1 - 3.8 7.0 6.2 2.2 7.7 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3087) Sugar_tr PF00083.24 OAG41794.1 - 1.2e-76 258.4 28.6 1.4e-76 258.2 28.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG41794.1 - 1e-24 87.2 47.0 6.5e-24 84.5 26.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ENTH PF01417.20 OAG41795.1 - 5.2e-32 110.5 0.6 9.2e-24 83.9 0.2 2.3 1 1 1 2 2 2 2 ENTH domain DUF5102 PF17104.5 OAG41795.1 - 0.02 14.9 6.9 0.024 14.7 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5102) Oxysterol_BP PF01237.18 OAG41796.1 - 1.7e-136 454.9 0.0 1.2e-135 452.2 0.0 2.0 2 0 0 2 2 2 1 Oxysterol-binding protein Ank_5 PF13857.6 OAG41796.1 - 7.1e-14 51.7 0.1 7.8e-08 32.5 0.0 3.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 OAG41796.1 - 4.2e-12 45.9 0.1 0.0053 17.2 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.7 OAG41796.1 - 4.5e-11 43.2 0.0 1.8e-06 28.4 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAG41796.1 - 4.5e-11 43.1 0.1 3.5e-05 24.3 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) PH PF00169.29 OAG41796.1 - 6.9e-11 42.6 0.5 6.9e-11 42.6 0.5 1.9 2 0 0 2 2 2 1 PH domain Ank_3 PF13606.6 OAG41796.1 - 7.7e-10 38.2 0.0 0.026 15.0 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat PH_8 PF15409.6 OAG41796.1 - 3.8e-07 30.3 0.5 9.1e-07 29.1 0.5 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 OAG41796.1 - 0.00012 22.5 1.1 0.00012 22.5 1.1 2.4 2 1 0 2 2 2 1 Pleckstrin homology domain PH_17 PF18012.1 OAG41796.1 - 0.11 12.3 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 PH domain DUF3176 PF11374.8 OAG41797.1 - 0.018 15.2 2.7 0.057 13.6 2.7 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3176) Pro_isomerase PF00160.21 OAG41798.1 - 7.1e-44 149.9 0.1 8.8e-44 149.6 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD GIT_SHD PF08518.11 OAG41799.1 - 1.2e-24 85.6 6.2 7.6e-14 51.0 0.6 2.6 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT ATG16 PF08614.11 OAG41799.1 - 6.8e-05 23.2 8.9 6.8e-05 23.2 8.9 3.9 3 1 0 3 3 2 1 Autophagy protein 16 (ATG16) GIT1_C PF12205.8 OAG41799.1 - 0.0001 22.4 0.1 0.0001 22.4 0.1 2.9 3 0 0 3 3 3 1 G protein-coupled receptor kinase-interacting protein 1 C term ADIP PF11559.8 OAG41799.1 - 0.003 17.6 5.8 0.003 17.6 5.8 3.9 4 1 0 4 4 4 1 Afadin- and alpha -actinin-Binding Baculo_PEP_C PF04513.12 OAG41799.1 - 0.018 15.1 0.4 0.018 15.1 0.4 3.2 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Prominin PF05478.11 OAG41799.1 - 0.085 10.8 5.4 0.95 7.3 0.0 2.3 2 0 0 2 2 2 0 Prominin Tropomyosin_1 PF12718.7 OAG41799.1 - 0.2 11.8 24.5 0.32 11.2 9.6 3.3 3 0 0 3 3 3 0 Tropomyosin like FAM76 PF16046.5 OAG41799.1 - 0.21 10.9 15.0 0.0082 15.5 7.2 2.3 2 0 0 2 2 2 0 FAM76 protein Pox_A_type_inc PF04508.12 OAG41799.1 - 0.26 11.2 5.9 0.45 10.4 0.5 3.4 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat APG6_N PF17675.1 OAG41799.1 - 0.6 10.6 30.0 1.3 9.5 7.3 3.1 1 1 0 2 2 2 0 Apg6 coiled-coil region Fez1 PF06818.15 OAG41799.1 - 0.79 10.1 22.5 16 5.9 18.3 3.0 2 1 1 3 3 3 0 Fez1 YABBY PF04690.13 OAG41799.1 - 0.79 10.3 4.7 0.4 11.2 1.9 2.0 2 0 0 2 2 1 0 YABBY protein FemAB PF02388.16 OAG41799.1 - 0.98 8.2 4.2 2 7.2 4.2 1.4 1 0 0 1 1 1 0 FemAB family Filament PF00038.21 OAG41799.1 - 1.1 8.8 28.6 0.36 10.4 3.8 3.1 2 1 1 3 3 3 0 Intermediate filament protein Syntaxin_2 PF14523.6 OAG41799.1 - 1.8 9.0 21.7 0.74 10.2 1.5 4.3 4 1 0 4 4 4 0 Syntaxin-like protein YabA PF06156.13 OAG41799.1 - 2 9.1 15.3 1.3 9.7 3.3 3.5 3 0 0 3 3 3 0 Initiation control protein YabA Spc7 PF08317.11 OAG41799.1 - 2.4 7.0 30.6 0.38 9.6 9.9 3.2 2 1 1 3 3 3 0 Spc7 kinetochore protein GAS PF13851.6 OAG41799.1 - 3.3 7.0 27.8 7.1 5.9 2.9 3.7 2 1 0 3 3 3 0 Growth-arrest specific micro-tubule binding DUF2203 PF09969.9 OAG41799.1 - 3.4 8.4 14.1 1 10.1 2.1 3.9 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2203) DUF1664 PF07889.12 OAG41799.1 - 4.6 7.3 14.4 7.1 6.7 2.9 3.8 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) HMG-CoA_red PF00368.18 OAG41800.1 - 9.3e-139 462.5 4.5 1.2e-138 462.1 4.5 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.6 OAG41800.1 - 2.1e-44 151.2 2.0 3.6e-44 150.4 2.0 1.4 1 0 0 1 1 1 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.8 OAG41800.1 - 3.3e-13 49.8 3.7 4.5e-07 29.8 0.4 2.7 2 0 0 2 2 2 2 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 OAG41800.1 - 0.00017 19.9 4.6 0.00017 19.9 4.6 1.4 2 0 0 2 2 2 1 Patched family RNase_PH PF01138.21 OAG41801.1 - 2.8e-36 124.9 0.9 5.8e-36 123.9 0.2 1.8 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 HLH PF00010.26 OAG41801.1 - 0.11 12.5 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain Sugar_tr PF00083.24 OAG41802.1 - 4.8e-88 296.0 24.6 5.5e-88 295.8 24.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG41802.1 - 3.2e-26 92.1 36.5 2.8e-20 72.6 9.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 OAG41802.1 - 0.00099 17.6 1.8 0.002 16.7 1.8 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) CDH-cyt PF16010.5 OAG41804.1 - 9.2e-27 93.9 0.5 1.6e-26 93.1 0.5 1.3 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase Cytochrom_B561 PF03188.16 OAG41804.1 - 2.1e-13 50.6 8.5 7.5e-13 48.8 5.9 2.2 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 DOMON PF03351.17 OAG41804.1 - 7.6e-05 22.9 0.2 0.00017 21.8 0.2 1.7 1 0 0 1 1 1 1 DOMON domain DUF2427 PF10348.9 OAG41804.1 - 0.0012 18.7 2.4 0.0012 18.7 2.4 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) DUF202 PF02656.15 OAG41804.1 - 0.0055 17.1 1.4 0.0055 17.1 1.4 3.4 4 0 0 4 4 4 1 Domain of unknown function (DUF202) DUF2776 PF10951.8 OAG41804.1 - 0.027 13.7 2.8 0.042 13.1 2.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2776) DUF1516 PF07457.11 OAG41804.1 - 0.036 14.3 1.1 0.036 14.3 1.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1516) PIRT PF15099.6 OAG41804.1 - 0.043 13.4 4.6 0.075 12.6 0.5 2.7 1 1 2 3 3 3 0 Phosphoinositide-interacting protein family DUF4083 PF13314.6 OAG41804.1 - 0.073 13.0 0.1 0.24 11.4 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) TMEMspv1-c74-12 PF11044.8 OAG41804.1 - 0.12 12.4 4.1 0.82 9.7 0.8 2.4 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein RCR PF12273.8 OAG41804.1 - 0.17 12.6 1.6 0.2 12.3 0.3 1.9 2 0 0 2 2 1 0 Chitin synthesis regulation, resistance to Congo red AzlD PF05437.12 OAG41804.1 - 0.85 9.8 8.2 0.064 13.4 1.2 2.4 2 1 0 2 2 2 0 Branched-chain amino acid transport protein (AzlD) Borrelia_P13 PF05628.12 OAG41804.1 - 0.93 9.4 8.7 0.047 13.6 2.4 2.1 2 0 0 2 2 2 0 Borrelia membrane protein P13 Tetraspanin PF00335.20 OAG41804.1 - 2.3 7.9 9.0 0.21 11.2 3.4 2.0 1 1 1 2 2 2 0 Tetraspanin family MerC PF03203.14 OAG41804.1 - 7.2 7.1 14.1 0.53 10.8 0.2 3.4 2 1 1 3 3 2 0 MerC mercury resistance protein HAMP PF00672.25 OAG41805.1 - 5.9e-38 129.0 30.1 5.4e-08 33.1 0.2 9.3 9 1 1 10 10 9 6 HAMP domain HATPase_c PF02518.26 OAG41805.1 - 4.9e-31 107.5 0.2 2.3e-30 105.4 0.2 2.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 OAG41805.1 - 1.2e-25 89.9 0.3 3.6e-25 88.3 0.3 2.0 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 OAG41805.1 - 2.5e-17 62.6 2.3 9.1e-17 60.9 0.3 3.3 3 0 0 3 3 2 1 His Kinase A (phospho-acceptor) domain Fungal_trans PF04082.18 OAG41805.1 - 1.2e-16 60.5 0.1 2.2e-16 59.7 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF4279 PF14106.6 OAG41805.1 - 0.00049 20.3 0.0 23 5.3 0.0 5.1 4 1 0 4 4 4 0 Domain of unknown function (DUF4279) Helo_like_N PF17111.5 OAG41805.1 - 0.022 14.1 1.6 7.1 5.9 0.1 3.2 2 0 0 2 2 2 0 Fungal N-terminal domain of STAND proteins Syntaxin_2 PF14523.6 OAG41805.1 - 0.054 13.9 20.1 2.1 8.8 0.0 7.0 4 2 3 8 8 8 0 Syntaxin-like protein DUF3829 PF12889.7 OAG41805.1 - 0.078 12.4 16.2 1.7 8.1 0.1 5.4 4 2 0 5 5 5 0 Protein of unknown function (DUF3829) APG6_N PF17675.1 OAG41805.1 - 0.12 12.9 3.7 0.4 11.2 1.9 2.9 2 0 0 2 2 2 0 Apg6 coiled-coil region Tho2 PF11262.8 OAG41805.1 - 0.23 10.6 2.1 0.65 9.1 2.1 1.7 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 GhoS PF11080.8 OAG41805.1 - 0.25 11.4 5.4 9 6.4 0.3 3.6 3 0 0 3 3 3 0 Endoribonuclease GhoS Atg14 PF10186.9 OAG41805.1 - 8.8 5.3 6.6 9.5 5.2 2.5 2.6 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 HATPase_c PF02518.26 OAG41807.1 - 1.6e-25 89.8 0.0 5.2e-24 84.9 0.0 2.4 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 OAG41807.1 - 4.3e-24 84.8 0.2 8.7e-24 83.9 0.2 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 OAG41807.1 - 5.9e-14 51.9 0.0 1.5e-13 50.6 0.0 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 OAG41807.1 - 0.0011 19.3 0.2 0.061 13.7 0.2 2.7 2 0 0 2 2 2 1 HAMP domain Campylo_MOMP PF05538.11 OAG41807.1 - 0.063 12.3 0.1 0.1 11.6 0.1 1.2 1 0 0 1 1 1 0 Campylobacter major outer membrane protein FAD_binding_7 PF03441.14 OAG41808.1 - 1.3e-78 263.1 0.4 2.3e-78 262.3 0.4 1.4 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 OAG41808.1 - 4.9e-39 134.0 0.0 8.4e-39 133.2 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase MFS_1 PF07690.16 OAG41809.1 - 2e-32 112.5 29.9 5e-24 84.9 2.5 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG41809.1 - 4e-10 39.2 0.9 4e-10 39.2 0.9 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 OAG41809.1 - 0.00032 19.2 0.2 0.00077 18.0 0.2 1.6 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 OAG41809.1 - 0.024 13.5 0.2 0.024 13.5 0.2 2.6 2 0 0 2 2 2 0 MFS_1 like family SDA1 PF05285.12 OAG41809.1 - 0.58 9.5 4.7 0.81 9.1 4.7 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 OAG41809.1 - 0.73 8.0 5.7 1 7.6 5.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Pox_RNA_Pol_19 PF05320.12 OAG41809.1 - 0.84 9.6 2.0 1.4 8.9 2.0 1.2 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit DUF2457 PF10446.9 OAG41809.1 - 1.6 7.8 8.7 2.2 7.3 8.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NMO PF03060.15 OAG41810.1 - 2e-28 99.8 14.7 5.8e-21 75.2 9.2 2.8 2 1 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.18 OAG41810.1 - 1.3e-06 27.7 1.8 1.8e-06 27.2 1.8 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 OAG41810.1 - 0.00067 18.8 8.9 0.0033 16.5 5.2 2.5 2 1 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 OAG41810.1 - 0.001 18.3 1.2 0.001 18.3 1.2 1.5 2 0 0 2 2 2 1 Conserved region in glutamate synthase His_biosynth PF00977.21 OAG41810.1 - 0.1 12.0 1.5 0.11 11.9 0.1 1.7 2 0 0 2 2 2 0 Histidine biosynthesis protein DUF561 PF04481.12 OAG41810.1 - 0.25 10.5 1.0 0.34 10.0 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF561) TFR_dimer PF04253.15 OAG41811.1 - 1.2e-29 102.8 0.1 2e-29 102.1 0.1 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 OAG41811.1 - 3.8e-22 79.0 0.0 5.8e-22 78.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 OAG41811.1 - 3e-10 40.0 0.0 1.2e-09 38.1 0.0 2.0 1 1 0 1 1 1 1 PA domain Nicastrin PF05450.15 OAG41811.1 - 0.0085 15.6 0.0 0.019 14.5 0.0 1.4 1 0 0 1 1 1 1 Nicastrin GFA PF04828.14 OAG41812.1 - 7.7e-22 77.5 0.7 1e-21 77.1 0.7 1.1 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Beta-lactamase PF00144.24 OAG41813.1 - 1.4e-53 182.3 0.1 2e-53 181.8 0.1 1.1 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.20 OAG41813.1 - 0.0041 16.6 0.0 0.0067 15.9 0.0 1.3 1 0 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase Beta-lactamase2 PF13354.6 OAG41813.1 - 0.0079 15.8 0.0 0.017 14.7 0.0 1.5 2 0 0 2 2 2 1 Beta-lactamase enzyme family Abhydrolase_3 PF07859.13 OAG41814.1 - 2.6e-67 226.7 0.0 3.5e-67 226.4 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 OAG41814.1 - 1.1e-10 41.0 0.2 3.2e-10 39.5 0.2 1.6 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 OAG41814.1 - 0.00027 20.5 0.0 0.0087 15.6 0.0 2.4 2 1 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 OAG41814.1 - 0.015 16.0 0.4 0.037 14.6 0.1 1.9 2 1 0 2 2 2 0 Alpha/beta hydrolase family Say1_Mug180 PF10340.9 OAG41814.1 - 0.038 12.8 0.0 0.05 12.5 0.0 1.1 1 0 0 1 1 1 0 Steryl acetyl hydrolase AXE1 PF05448.12 OAG41814.1 - 0.042 12.5 0.1 6.8 5.3 0.1 2.2 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Hydrolase_4 PF12146.8 OAG41814.1 - 0.043 13.1 0.0 2.1 7.6 0.0 2.6 2 1 0 3 3 3 0 Serine aminopeptidase, S33 Esterase_phd PF10503.9 OAG41814.1 - 0.14 11.6 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 Esterase PHB depolymerase Amidase PF01425.21 OAG41815.1 - 3e-24 85.8 0.0 2.5e-15 56.4 0.0 3.1 1 1 1 2 2 2 2 Amidase TctB PF07331.11 OAG41817.1 - 0.0036 17.6 3.1 0.0054 17.0 3.1 1.2 1 0 0 1 1 1 1 Tripartite tricarboxylate transporter TctB family APCDDC PF14921.6 OAG41817.1 - 0.02 14.3 0.0 0.03 13.8 0.0 1.2 1 0 0 1 1 1 0 Adenomatosis polyposis coli down-regulated 1 SdpI PF13630.6 OAG41817.1 - 0.47 10.6 4.6 0.77 9.9 4.0 1.7 1 1 0 1 1 1 0 SdpI/YhfL protein family SP_C-Propep PF08999.10 OAG41817.1 - 0.98 9.2 3.0 1.7 8.5 2.2 1.7 2 0 0 2 2 2 0 Surfactant protein C, N terminal propeptide HemY_N PF07219.13 OAG41817.1 - 2.2 8.5 10.3 0.15 12.2 3.6 2.2 1 1 1 2 2 2 0 HemY protein N-terminus DJ-1_PfpI PF01965.24 OAG41819.1 - 2.5e-06 27.4 0.0 1.1e-05 25.2 0.0 2.0 2 1 0 2 2 2 1 DJ-1/PfpI family SWIRM PF04433.17 OAG41820.1 - 0.06 13.7 0.0 0.28 11.6 0.0 2.2 1 1 0 1 1 1 0 SWIRM domain CAML PF14963.6 OAG41820.1 - 1.6 8.8 4.0 3.1 7.8 4.0 1.5 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand NPIP PF06409.11 OAG41821.1 - 1 8.3 3.6 1.7 7.7 3.6 1.2 1 0 0 1 1 1 0 Nuclear pore complex interacting protein (NPIP) Dynamin_M PF01031.20 OAG41822.1 - 2.3e-104 348.6 0.0 3.9e-104 347.9 0.0 1.4 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 OAG41822.1 - 3.7e-57 193.1 0.5 8.1e-57 191.9 0.1 1.8 2 0 0 2 2 2 1 Dynamin family GED PF02212.18 OAG41822.1 - 7.2e-31 106.2 6.4 2e-30 104.8 6.4 1.8 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 OAG41822.1 - 8.2e-05 22.7 1.0 0.00054 20.0 1.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_15 PF13175.6 OAG41822.1 - 0.048 13.4 1.7 2.6 7.7 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain AIG1 PF04548.16 OAG41822.1 - 0.056 12.8 0.2 5.7 6.2 0.0 2.5 2 0 0 2 2 2 0 AIG1 family FeoB_N PF02421.18 OAG41822.1 - 0.092 12.3 0.6 7.8 6.0 0.1 2.7 3 0 0 3 3 3 0 Ferrous iron transport protein B WD40 PF00400.32 OAG41823.1 - 1.7e-24 85.6 8.1 4.5e-05 24.1 0.6 7.4 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG41823.1 - 1.3e-10 41.4 2.8 0.00034 20.8 0.1 5.5 1 1 4 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OAG41823.1 - 3.4e-06 26.2 0.9 0.0007 18.6 0.1 3.1 1 1 2 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 OAG41823.1 - 0.0031 15.9 0.1 0.0046 15.3 0.1 1.2 1 0 0 1 1 1 1 WD repeat-containing and planar cell polarity effector protein Fritz Cytochrom_D1 PF02239.16 OAG41823.1 - 0.016 13.8 0.1 0.75 8.3 0.0 2.3 2 0 0 2 2 2 0 Cytochrome D1 heme domain eIF2A PF08662.11 OAG41823.1 - 0.019 14.8 2.1 0.18 11.7 0.3 2.7 2 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A DPPIV_N PF00930.21 OAG41823.1 - 0.023 13.5 0.3 0.16 10.7 0.2 2.1 1 1 0 1 1 1 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region DUF4221 PF13970.6 OAG41823.1 - 0.028 14.0 0.0 0.094 12.3 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4221) WD40_like PF17005.5 OAG41823.1 - 0.067 12.5 0.0 0.15 11.3 0.0 1.5 2 0 0 2 2 2 0 WD40-like domain CDC24_OB3 PF17244.2 OAG41823.1 - 0.099 12.3 0.5 0.25 11.0 0.4 1.6 1 1 1 2 2 2 0 Cell division control protein 24, OB domain 3 ATP-synt_ab PF00006.25 OAG41824.1 - 1.4e-105 351.6 0.0 2e-105 351.1 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain Hom_end_hint PF05203.16 OAG41824.1 - 5.7e-81 271.8 0.0 8.6e-81 271.2 0.0 1.3 1 0 0 1 1 1 1 Hom_end-associated Hint ATP-synt_ab_Xtn PF16886.5 OAG41824.1 - 1.4e-46 157.3 0.0 2.9e-46 156.3 0.0 1.6 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension Hom_end PF05204.14 OAG41824.1 - 9.7e-30 103.0 0.0 9.6e-28 96.5 0.1 2.5 2 0 0 2 2 2 1 Homing endonuclease ATP-synt_ab_N PF02874.23 OAG41824.1 - 3.5e-14 53.1 2.4 7.9e-14 51.9 2.4 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Hint_2 PF13403.6 OAG41824.1 - 0.00014 22.2 0.0 0.00057 20.2 0.0 2.0 2 0 0 2 2 2 1 Hint domain Hint PF01079.20 OAG41824.1 - 0.00022 20.8 0.0 0.00046 19.8 0.0 1.4 1 0 0 1 1 1 1 Hint module Vint PF14623.6 OAG41824.1 - 0.0065 16.3 0.0 0.018 14.9 0.0 1.7 2 0 0 2 2 2 1 Hint-domain HSBP1 PF06825.12 OAG41824.1 - 0.083 12.8 0.0 0.23 11.3 0.0 1.8 1 0 0 1 1 1 0 Heat shock factor binding protein 1 ORC5_C PF14630.6 OAG41826.1 - 7.9e-58 196.2 0.5 1.3e-57 195.5 0.5 1.3 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.6 OAG41826.1 - 7.2e-07 29.7 0.1 1.9e-06 28.4 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain PUF PF00806.19 OAG41827.1 - 6.2e-59 192.5 3.3 1.2e-09 37.4 0.1 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat CPL PF08144.11 OAG41827.1 - 0.14 12.5 0.2 18 5.7 0.0 3.8 1 1 1 3 3 3 0 CPL (NUC119) domain Csm1_B PF18211.1 OAG41827.1 - 0.15 11.9 0.0 0.4 10.6 0.0 1.7 1 0 0 1 1 1 0 Csm1 subunit domain B RNA_pol_Rpb2_6 PF00562.28 OAG41828.1 - 3.3e-125 418.2 0.0 5.8e-125 417.4 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 OAG41828.1 - 5.4e-57 192.6 0.2 7.8e-57 192.1 0.2 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 OAG41828.1 - 3e-30 104.5 0.2 8.5e-30 103.0 0.2 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 OAG41828.1 - 8.4e-28 97.3 1.0 1.9e-27 96.2 1.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.13 OAG41828.1 - 2.4e-24 85.4 0.2 4.9e-24 84.4 0.2 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 OAG41828.1 - 4.7e-19 68.3 0.0 1.1e-18 67.1 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 OAG41828.1 - 1.3e-12 48.1 0.2 4.3e-12 46.4 0.2 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Pkinase PF00069.25 OAG41829.1 - 3.6e-06 26.5 0.0 0.12 11.7 0.0 3.2 2 1 0 2 2 2 2 Protein kinase domain ADH_zinc_N PF00107.26 OAG41830.1 - 1.3e-23 83.4 1.0 2.6e-23 82.4 1.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG41830.1 - 1.1e-21 76.7 2.8 3.2e-21 75.2 2.8 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 OAG41830.1 - 0.00095 20.2 0.2 0.0018 19.3 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 OAG41830.1 - 0.074 12.5 0.8 0.14 11.6 0.5 1.7 2 0 0 2 2 2 0 short chain dehydrogenase 3HCDH_N PF02737.18 OAG41830.1 - 0.089 12.7 0.4 0.16 11.9 0.4 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Tim17 PF02466.19 OAG41831.1 - 5e-39 133.1 4.9 8.5e-39 132.4 4.9 1.4 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family ABA_WDS PF02496.16 OAG41831.1 - 0.54 10.8 3.1 4.1 7.9 0.5 2.9 2 2 1 3 3 3 0 ABA/WDS induced protein DUF4766 PF15973.5 OAG41831.1 - 2.1 9.0 6.3 2.8 8.5 6.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4766) SRP54 PF00448.22 OAG41832.1 - 8.1e-71 237.7 2.6 8.1e-71 237.7 2.6 1.8 3 0 0 3 3 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 OAG41832.1 - 9.8e-31 106.3 2.9 9.8e-31 106.3 2.9 3.9 3 1 1 4 4 4 1 Signal peptide binding domain SRP54_N PF02881.19 OAG41832.1 - 2.9e-18 65.9 0.2 7.7e-18 64.5 0.0 1.9 2 0 0 2 2 1 1 SRP54-type protein, helical bundle domain AAA_33 PF13671.6 OAG41832.1 - 1.9e-05 24.8 0.3 4.9e-05 23.5 0.0 2.0 2 0 0 2 2 1 1 AAA domain cobW PF02492.19 OAG41832.1 - 0.00017 21.2 0.7 0.00071 19.2 0.7 2.1 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 OAG41832.1 - 0.00037 20.9 0.0 0.00075 19.9 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 OAG41832.1 - 0.00041 19.7 0.0 0.00077 18.8 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin 6PF2K PF01591.18 OAG41832.1 - 0.00049 19.5 0.0 0.001 18.4 0.0 1.5 1 0 0 1 1 1 1 6-phosphofructo-2-kinase AAA_17 PF13207.6 OAG41832.1 - 0.00053 20.4 3.2 0.00082 19.8 0.0 2.7 3 0 0 3 3 3 1 AAA domain CbiA PF01656.23 OAG41832.1 - 0.0009 19.3 0.0 0.0024 17.9 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain APS_kinase PF01583.20 OAG41832.1 - 0.0018 18.2 0.0 0.0053 16.7 0.0 1.8 1 0 0 1 1 1 1 Adenylylsulphate kinase MeaB PF03308.16 OAG41832.1 - 0.0019 17.2 0.8 0.0071 15.4 0.0 2.2 3 0 0 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 OAG41832.1 - 0.0036 17.0 0.1 0.0036 17.0 0.1 2.1 2 1 0 2 2 2 1 AAA domain SRPRB PF09439.10 OAG41832.1 - 0.0049 16.3 0.8 3.7 7.0 0.5 3.3 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit ResIII PF04851.15 OAG41832.1 - 0.0064 16.5 0.1 0.023 14.7 0.1 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit TPP_enzyme_N PF02776.18 OAG41832.1 - 0.011 15.4 0.4 0.15 11.7 0.1 2.4 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain AAA_24 PF13479.6 OAG41832.1 - 0.014 15.1 0.3 0.07 12.9 0.1 2.2 3 0 0 3 3 3 0 AAA domain Thymidylate_kin PF02223.17 OAG41832.1 - 0.021 14.5 0.1 0.06 13.0 0.1 1.7 1 0 0 1 1 1 0 Thymidylate kinase MobB PF03205.14 OAG41832.1 - 0.041 13.8 0.2 0.15 12.0 0.0 2.1 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.6 OAG41832.1 - 0.046 14.0 0.1 0.14 12.5 0.1 1.8 1 0 0 1 1 1 0 AAA domain AAA_31 PF13614.6 OAG41832.1 - 0.048 13.6 0.0 0.14 12.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 OAG41832.1 - 0.053 13.3 0.3 0.26 11.0 0.1 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 OAG41832.1 - 0.063 13.6 0.6 0.34 11.2 0.2 2.4 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.6 OAG41832.1 - 0.082 13.5 0.0 0.19 12.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 OAG41832.1 - 0.089 13.0 0.1 0.18 12.0 0.1 1.6 1 0 0 1 1 1 0 AAA domain Arf PF00025.21 OAG41832.1 - 0.12 11.8 0.0 0.4 10.1 0.0 1.8 2 0 0 2 2 2 0 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OAG41832.1 - 0.13 12.3 0.2 1.7 8.8 0.1 2.8 2 1 0 2 2 2 0 50S ribosome-binding GTPase Rrp15p PF07890.12 OAG41833.1 - 1.3e-37 129.1 13.3 1.3e-37 129.1 13.3 2.5 2 1 0 2 2 2 1 Rrp15p Fer2 PF00111.27 OAG41834.1 - 0.0084 16.0 0.2 0.83 9.7 0.1 2.3 1 1 1 2 2 2 2 2Fe-2S iron-sulfur cluster binding domain Glyco_hydro_71 PF03659.14 OAG41835.1 - 1.2e-129 432.4 6.1 1.6e-129 432.0 6.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Mito_carr PF00153.27 OAG41836.1 - 5.1e-13 48.8 4.4 0.0018 18.1 0.1 5.1 3 2 0 3 3 3 3 Mitochondrial carrier protein bZIP_1 PF00170.21 OAG41837.1 - 4.1e-07 30.0 8.8 4.1e-07 30.0 8.8 2.0 1 1 1 2 2 2 1 bZIP transcription factor Hap4_Hap_bind PF10297.9 OAG41837.1 - 6.1e-07 29.4 6.7 6.1e-07 29.4 6.7 1.8 2 0 0 2 2 1 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 DUF812 PF05667.11 OAG41837.1 - 0.00053 19.0 0.7 0.00082 18.4 0.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF812) DUF2408 PF10303.9 OAG41837.1 - 0.071 13.7 0.9 0.13 12.8 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) KLRAQ PF10205.9 OAG41837.1 - 0.073 13.3 1.5 0.14 12.4 1.5 1.4 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein Fmp27_WPPW PF10359.9 OAG41837.1 - 0.11 11.3 2.7 0.17 10.7 2.7 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain dsrm PF00035.26 OAG41837.1 - 0.13 13.0 0.0 0.31 11.8 0.0 1.6 1 0 0 1 1 1 0 Double-stranded RNA binding motif Golgin_A5 PF09787.9 OAG41837.1 - 0.13 11.7 4.1 0.21 11.0 4.1 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 Dna2 PF08696.11 OAG41837.1 - 0.17 11.7 0.3 0.26 11.1 0.3 1.2 1 0 0 1 1 1 0 DNA replication factor Dna2 Jnk-SapK_ap_N PF09744.9 OAG41837.1 - 0.4 10.9 7.4 0.8 9.9 7.4 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 FTA4 PF13093.6 OAG41837.1 - 0.46 10.3 3.2 0.74 9.7 2.7 1.6 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DUF4094 PF13334.6 OAG41837.1 - 0.62 10.5 2.9 4.7 7.7 2.9 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4094) DUF4407 PF14362.6 OAG41837.1 - 1 8.7 3.6 2 7.7 3.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) V_ATPase_I PF01496.19 OAG41837.1 - 1.4 6.7 2.9 1.9 6.3 2.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family bZIP_2 PF07716.15 OAG41837.1 - 3.9 7.6 17.7 0.52 10.4 11.7 2.4 2 1 0 2 2 2 0 Basic region leucine zipper bZIP_Maf PF03131.17 OAG41837.1 - 8.3 7.0 10.6 23 5.6 9.2 2.3 1 1 1 2 2 2 0 bZIP Maf transcription factor PhoD PF09423.10 OAG41838.1 - 5.1e-38 131.0 0.0 1.4e-37 129.5 0.0 1.8 1 1 0 1 1 1 1 PhoD-like phosphatase Pur_ac_phosph_N PF16656.5 OAG41838.1 - 0.029 14.9 0.2 0.086 13.4 0.2 1.8 1 0 0 1 1 1 0 Purple acid Phosphatase, N-terminal domain Glyco_hydro_18 PF00704.28 OAG41839.1 - 4.3e-17 62.8 0.0 6.2e-17 62.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 IDO PF01231.18 OAG41840.1 - 3.2e-14 52.6 0.0 1.3e-13 50.6 0.0 1.9 2 0 0 2 2 2 1 Indoleamine 2,3-dioxygenase NAD_binding_1 PF00175.21 OAG41840.1 - 6.2e-11 42.9 0.0 1.6e-10 41.6 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_1 PF00667.20 OAG41840.1 - 2.2e-10 40.5 0.0 9.7e-10 38.4 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.28 OAG41840.1 - 3.1e-10 40.0 0.0 1.1e-09 38.3 0.0 2.0 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain SGL PF08450.12 OAG41841.1 - 8.6e-26 91.0 0.4 6.9e-25 88.1 0.4 2.1 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 OAG41841.1 - 0.005 16.9 0.0 0.046 13.8 0.0 2.6 2 1 0 2 2 2 1 Strictosidine synthase PD40 PF07676.12 OAG41841.1 - 0.011 15.7 0.1 0.038 14.0 0.0 2.0 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat NHL PF01436.21 OAG41841.1 - 0.034 14.2 1.5 1.2 9.3 0.0 3.6 4 0 0 4 4 4 0 NHL repeat HpcH_HpaI PF03328.14 OAG41842.1 - 2e-35 122.0 0.0 2.8e-35 121.5 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family HET PF06985.11 OAG41843.1 - 1.3e-29 103.4 0.4 2e-29 102.9 0.4 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HCV_NS5a_1a PF08300.13 OAG41843.1 - 0.062 13.4 0.1 0.13 12.4 0.1 1.4 1 0 0 1 1 1 0 Hepatitis C virus non-structural 5a zinc finger domain NPCC PF08058.11 OAG41844.1 - 7e-20 71.4 0.0 1.1e-19 70.8 0.0 1.3 1 0 0 1 1 1 1 Nuclear pore complex component Anticodon_1 PF08264.13 OAG41844.1 - 0.27 11.2 0.3 0.48 10.4 0.0 1.5 2 0 0 2 2 2 0 Anticodon-binding domain of tRNA Hid1 PF12722.7 OAG41845.1 - 3e-295 981.6 0.0 9.8e-295 979.9 0.0 1.7 1 1 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 OAG41845.1 - 1.2e-98 331.2 0.0 1.5e-98 330.9 0.0 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein DUF4820 PF16091.5 OAG41845.1 - 0.0019 17.6 0.0 0.0036 16.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4820) RTA1 PF04479.13 OAG41846.1 - 1.2e-65 221.1 5.6 1.5e-65 220.7 5.6 1.1 1 0 0 1 1 1 1 RTA1 like protein NMO PF03060.15 OAG41847.1 - 9.5e-54 183.0 0.5 7.9e-53 180.0 0.5 1.9 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 OAG41847.1 - 2.9e-14 52.8 0.0 6.9e-07 28.6 0.0 2.1 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 OAG41847.1 - 0.0014 17.7 0.9 0.0026 16.8 0.9 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase His_biosynth PF00977.21 OAG41847.1 - 0.036 13.5 0.4 0.93 8.9 0.1 2.4 2 0 0 2 2 2 0 Histidine biosynthesis protein Glu_synthase PF01645.17 OAG41847.1 - 0.11 11.6 1.4 0.32 10.1 1.4 1.9 1 1 0 1 1 1 0 Conserved region in glutamate synthase FAD_binding_3 PF01494.19 OAG41848.1 - 4.7e-22 78.7 0.4 4.8e-21 75.4 0.4 2.0 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAG41848.1 - 5.4e-09 36.1 4.5 0.00014 21.6 2.4 2.4 1 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG41848.1 - 6.4e-09 35.5 1.3 1.2e-05 24.8 0.7 2.1 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG41848.1 - 7.4e-06 26.1 0.8 1.7e-05 25.0 0.8 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 OAG41848.1 - 9.9e-06 24.9 2.3 2e-05 23.9 2.3 1.5 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.14 OAG41848.1 - 9.9e-05 21.4 0.4 0.054 12.3 0.0 2.2 2 0 0 2 2 2 2 Tryptophan halogenase Amino_oxidase PF01593.24 OAG41848.1 - 0.0001 21.7 1.0 0.12 11.6 0.2 2.2 1 1 1 2 2 2 2 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 OAG41848.1 - 0.00013 21.1 1.4 0.0014 17.7 1.4 2.1 1 1 0 1 1 1 1 Lycopene cyclase protein GIDA PF01134.22 OAG41848.1 - 0.00047 19.3 1.0 0.0029 16.8 1.0 1.9 1 1 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.27 OAG41848.1 - 0.00077 20.0 1.0 0.0041 17.6 0.8 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAG41848.1 - 0.0028 16.9 0.2 0.0052 16.1 0.2 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 OAG41848.1 - 0.0034 16.7 0.0 0.017 14.4 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 OAG41848.1 - 0.0056 16.0 0.0 0.0086 15.4 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 OAG41848.1 - 0.0075 15.0 0.5 0.014 14.2 0.5 1.4 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.7 OAG41848.1 - 0.021 14.2 2.5 0.034 13.5 2.5 1.5 1 1 0 1 1 1 0 FAD dependent oxidoreductase ApbA PF02558.16 OAG41848.1 - 0.068 12.8 0.1 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA SE PF08491.10 OAG41848.1 - 0.075 12.1 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Squalene epoxidase SCF PF02404.15 OAG41849.1 - 7.5e-05 22.2 3.1 0.97 8.7 0.1 3.8 2 1 1 3 3 3 3 Stem cell factor PhoU PF01895.19 OAG41849.1 - 0.12 12.9 2.3 0.53 10.8 2.2 2.3 1 1 0 1 1 1 0 PhoU domain DUF615 PF04751.14 OAG41849.1 - 3.5 7.6 9.7 5.5 7.0 4.2 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF615) Nbl1_Borealin_N PF10444.9 OAG41849.1 - 6.3 6.5 8.4 0.69 9.6 2.2 2.6 3 0 0 3 3 3 0 Nbl1 / Borealin N terminal AAA PF00004.29 OAG41850.1 - 3.5e-19 69.6 0.0 8.5e-19 68.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 OAG41850.1 - 0.00014 21.7 0.0 0.00032 20.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OAG41850.1 - 0.0002 21.8 1.4 0.00069 20.0 0.2 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 OAG41850.1 - 0.0011 19.3 0.2 0.0092 16.3 0.0 2.3 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 OAG41850.1 - 0.0033 17.2 0.0 0.0056 16.4 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 OAG41850.1 - 0.0073 16.3 0.0 0.017 15.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 OAG41850.1 - 0.015 15.8 0.1 0.18 12.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain tRNA-synt_1c PF00749.21 OAG41850.1 - 0.081 11.8 0.0 1.6 7.6 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain AAA_14 PF13173.6 OAG41850.1 - 0.088 12.8 0.0 0.33 11.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 OAG41850.1 - 0.14 12.6 0.0 0.54 10.7 0.0 2.1 2 0 0 2 2 1 0 RNA helicase ATPase_2 PF01637.18 OAG41850.1 - 0.34 10.8 2.0 1.2 9.0 0.1 2.5 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea AMP-binding PF00501.28 OAG41851.1 - 2.3e-13 49.5 0.0 7.5e-07 28.1 0.0 2.0 2 0 0 2 2 2 2 AMP-binding enzyme Oest_recep PF02159.15 OAG41851.1 - 0.029 14.8 1.1 0.62 10.6 0.6 2.4 2 0 0 2 2 2 0 Oestrogen receptor Syntaxin-6_N PF09177.11 OAG41855.1 - 1.2e-28 99.5 0.2 2.6e-28 98.5 0.2 1.5 1 0 0 1 1 1 1 Syntaxin 6, N-terminal SNARE PF05739.19 OAG41855.1 - 0.0039 17.1 0.9 0.0082 16.1 0.9 1.6 1 0 0 1 1 1 1 SNARE domain NPV_P10 PF05531.12 OAG41855.1 - 0.012 16.1 3.3 16 6.1 0.1 3.3 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein GCIP PF13324.6 OAG41855.1 - 0.015 14.9 3.5 0.026 14.2 3.0 1.7 1 1 0 1 1 1 0 Grap2 and cyclin-D-interacting Snapin_Pallidin PF14712.6 OAG41855.1 - 0.87 10.0 3.2 1.8 9.0 0.2 2.6 2 1 0 2 2 2 0 Snapin/Pallidin DUF948 PF06103.11 OAG41855.1 - 4 7.8 13.5 16 5.9 0.0 4.5 3 2 1 4 4 4 0 Bacterial protein of unknown function (DUF948) TolA_bind_tri PF16331.5 OAG41855.1 - 7.8 6.7 9.7 10 6.3 3.4 2.8 3 0 0 3 3 3 0 TolA binding protein trimerisation NAP PF00956.18 OAG41856.1 - 1.3e-19 70.5 2.6 2.7e-19 69.4 2.2 1.7 1 1 0 1 1 1 1 Nucleosome assembly protein (NAP) Drc1-Sld2 PF11719.8 OAG41856.1 - 0.098 12.2 6.2 0.053 13.1 3.9 1.7 2 0 0 2 2 2 0 DNA replication and checkpoint protein Voldacs PF03517.13 OAG41856.1 - 0.74 9.9 9.5 1.3 9.2 9.5 1.4 1 0 0 1 1 1 0 Regulator of volume decrease after cellular swelling PGA2 PF07543.12 OAG41856.1 - 1.8 8.6 6.8 4.2 7.4 1.5 2.3 2 0 0 2 2 2 0 Protein trafficking PGA2 BUD22 PF09073.10 OAG41856.1 - 4.4 6.5 9.8 5.7 6.2 9.8 1.2 1 0 0 1 1 1 0 BUD22 AA_permease_2 PF13520.6 OAG41857.1 - 1.1e-52 179.4 57.3 1.4e-52 179.0 57.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAG41857.1 - 4.5e-19 68.4 45.3 6.5e-19 67.9 45.3 1.1 1 0 0 1 1 1 1 Amino acid permease PMP1_2 PF08114.11 OAG41857.1 - 0.081 12.7 3.1 8.9 6.2 0.1 3.3 2 0 0 2 2 2 0 ATPase proteolipid family ERG4_ERG24 PF01222.17 OAG41859.1 - 2.8e-144 481.1 21.2 3.2e-144 480.9 21.2 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF4808 PF16066.5 OAG41860.1 - 0.0065 17.0 0.1 0.014 15.9 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4808) DUF5305 PF17231.2 OAG41860.1 - 0.011 15.2 0.0 0.024 14.0 0.0 1.5 1 1 0 1 1 1 0 Family of unknown function (DUF5305) NmrA PF05368.13 OAG41861.1 - 3.2e-09 36.7 0.0 4.6e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 OAG41861.1 - 0.0098 16.2 0.0 0.02 15.1 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Methyltransf_23 PF13489.6 OAG41862.1 - 1.5e-20 73.7 0.0 2.3e-20 73.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG41862.1 - 1.8e-10 41.4 0.0 5.5e-10 39.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG41862.1 - 4.2e-08 33.7 0.0 8.5e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG41862.1 - 6.4e-05 23.6 0.0 0.0012 19.5 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG41862.1 - 7.6e-05 22.5 0.0 0.02 14.7 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_2 PF00891.18 OAG41862.1 - 0.00039 19.8 0.0 0.015 14.6 0.0 2.3 2 0 0 2 2 2 1 O-methyltransferase domain MTS PF05175.14 OAG41862.1 - 0.0029 17.2 0.0 0.0073 15.9 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_16 PF10294.9 OAG41862.1 - 0.0045 16.7 0.0 0.0073 16.1 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Ubie_methyltran PF01209.18 OAG41862.1 - 0.0052 16.2 0.0 0.12 11.6 0.0 2.6 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family PrmA PF06325.13 OAG41862.1 - 0.0057 16.1 0.0 0.0085 15.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.19 OAG41862.1 - 0.0066 16.6 0.0 0.02 15.0 0.0 1.6 1 1 0 2 2 2 1 FtsJ-like methyltransferase DUF938 PF06080.12 OAG41862.1 - 0.0072 16.1 0.0 0.027 14.2 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF938) Methyltransf_4 PF02390.17 OAG41862.1 - 0.025 14.1 0.0 0.1 12.1 0.0 1.9 2 0 0 2 2 2 0 Putative methyltransferase p450 PF00067.22 OAG41863.1 - 3.7e-58 197.4 0.0 4.8e-58 197.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ceramidase PF05875.12 OAG41864.1 - 3e-64 217.0 12.9 3.4e-64 216.8 12.9 1.0 1 0 0 1 1 1 1 Ceramidase DUF4212 PF13937.6 OAG41864.1 - 0.0079 16.5 0.3 0.0079 16.5 0.3 3.1 3 1 0 3 3 3 1 Domain of unknown function (DUF4212) Leader_Trp PF08255.11 OAG41864.1 - 0.036 14.0 1.0 0.17 11.9 1.0 2.2 1 0 0 1 1 1 0 Trp-operon Leader Peptide adh_short_C2 PF13561.6 OAG41865.1 - 6.6e-48 163.3 0.0 8.2e-48 163.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG41865.1 - 5e-39 133.8 0.0 6.3e-39 133.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG41865.1 - 3.9e-11 43.2 0.0 6.3e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG41865.1 - 0.1 12.0 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family GST_N_3 PF13417.6 OAG41866.1 - 2.6e-07 31.0 0.0 4.9e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAG41866.1 - 0.00014 21.8 0.3 0.0003 20.8 0.1 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain TPP_enzyme_N PF02776.18 OAG41867.1 - 7.8e-44 149.3 0.0 1.6e-43 148.3 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 OAG41867.1 - 6.2e-24 84.5 0.0 1.7e-23 83.1 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 OAG41867.1 - 2e-22 79.4 0.1 1.5e-21 76.6 0.0 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain 60KD_IMP PF02096.20 OAG41868.1 - 4.6e-19 68.9 0.8 4.6e-19 68.9 0.8 2.0 2 0 0 2 2 2 1 60Kd inner membrane protein DUF4723 PF15851.5 OAG41868.1 - 0.0016 18.5 0.2 0.0041 17.2 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4723) DUF5403 PF17395.2 OAG41868.1 - 0.11 12.8 0.0 0.43 10.9 0.0 2.0 1 0 0 1 1 1 0 Family of unknown function (DUF5403) SEP PF08059.13 OAG41869.1 - 6e-26 90.8 0.2 1.4e-25 89.7 0.2 1.7 1 0 0 1 1 1 1 SEP domain UBA_4 PF14555.6 OAG41869.1 - 5.7e-13 48.5 1.0 9.1e-13 47.8 1.0 1.3 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 OAG41869.1 - 4e-11 43.0 0.0 6.8e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 UBX domain AMP-binding PF00501.28 OAG41870.1 - 1.4e-36 126.1 0.0 2e-36 125.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 OAG41870.1 - 1.2e-06 28.3 0.0 2.3e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 OAG41870.1 - 0.026 15.5 0.0 0.052 14.5 0.0 1.6 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain BCS1_N PF08740.11 OAG41872.1 - 3.8e-32 111.8 2.3 8.1e-32 110.7 1.5 1.9 2 0 0 2 2 2 1 BCS1 N terminal AAA PF00004.29 OAG41872.1 - 1.3e-14 54.8 0.0 3.8e-06 27.3 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 OAG41872.1 - 0.11 11.9 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 KaiC RuvB_N PF05496.12 OAG41872.1 - 0.11 12.2 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Fungal_trans PF04082.18 OAG41873.1 - 1.2e-13 50.7 0.0 2.1e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG41873.1 - 4.8e-08 33.0 8.6 1.1e-07 31.9 8.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zincin_2 PF10103.9 OAG41873.1 - 0.04 13.2 0.0 0.062 12.6 0.0 1.2 1 0 0 1 1 1 0 Zincin-like metallopeptidase Ribosomal_L4 PF00573.22 OAG41874.1 - 7.5e-35 120.4 0.3 9.8e-35 120.0 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 OAG41874.1 - 4.1e-29 100.5 2.5 4.4e-29 100.3 0.2 2.1 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain MFS_1 PF07690.16 OAG41875.1 - 1.5e-06 27.4 29.3 0.00011 21.3 26.3 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Sec6 PF06046.13 OAG41876.1 - 1.3e-150 502.5 5.0 2.6e-150 501.6 5.0 1.5 1 0 0 1 1 1 1 Exocyst complex component Sec6 Vps53_N PF04100.12 OAG41876.1 - 0.003 16.6 5.5 0.0087 15.1 0.5 2.6 2 1 0 2 2 2 1 Vps53-like, N-terminal LOH1CR12 PF10158.9 OAG41876.1 - 0.12 12.3 0.5 0.78 9.8 0.1 2.5 2 0 0 2 2 2 0 Tumour suppressor protein PAS_3 PF08447.12 OAG41876.1 - 0.16 12.3 0.7 0.81 10.0 0.1 2.6 2 0 0 2 2 2 0 PAS fold THOC7 PF05615.13 OAG41876.1 - 0.93 9.8 9.9 0.87 9.9 0.1 3.8 4 0 0 4 4 4 0 Tho complex subunit 7 Phage_Mu_Gam PF07352.12 OAG41876.1 - 1.1 9.2 4.5 29 4.5 0.1 3.6 3 0 0 3 3 3 0 Bacteriophage Mu Gam like protein Aa_trans PF01490.18 OAG41877.1 - 1.3e-42 146.0 33.2 1.5e-42 145.8 33.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Aminotran_1_2 PF00155.21 OAG41879.1 - 4.7e-68 230.0 0.0 5.4e-68 229.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II MFS_1 PF07690.16 OAG41880.1 - 8.3e-33 113.8 15.6 8.3e-33 113.8 15.6 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 OAG41880.1 - 0.00045 19.6 1.3 0.00045 19.6 1.3 2.1 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB DUF2754 PF10953.8 OAG41880.1 - 0.048 13.9 0.1 0.21 11.9 0.1 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2754) Fungal_trans_2 PF11951.8 OAG41881.1 - 0.41 9.4 7.2 1.5 7.5 7.1 2.0 1 1 0 1 1 1 0 Fungal specific transcription factor domain BTB PF00651.31 OAG41882.1 - 3.4e-16 59.5 0.1 5.7e-16 58.7 0.1 1.3 1 0 0 1 1 1 1 BTB/POZ domain HypA PF01155.19 OAG41882.1 - 0.045 13.8 0.6 0.086 12.9 0.6 1.5 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Methyltransf_11 PF08241.12 OAG41883.1 - 2.9e-16 59.9 0.2 4.9e-16 59.2 0.2 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG41883.1 - 3.4e-16 59.7 0.2 6.3e-16 58.9 0.2 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG41883.1 - 2.9e-12 46.6 0.0 4.4e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAG41883.1 - 2.7e-09 37.1 0.0 3.6e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG41883.1 - 1.4e-07 32.2 0.0 2.7e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 OAG41883.1 - 5.4e-07 29.4 0.3 8.3e-07 28.8 0.3 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW PrmA PF06325.13 OAG41883.1 - 6.4e-07 29.1 0.1 8.4e-07 28.7 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 OAG41883.1 - 1.6e-06 27.7 0.2 2.6e-06 27.0 0.2 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 OAG41883.1 - 2e-06 27.5 0.0 3e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain ADH_zinc_N PF00107.26 OAG41883.1 - 0.0026 17.7 0.4 0.0083 16.1 0.4 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_16 PF10294.9 OAG41883.1 - 0.0097 15.6 0.1 0.015 15.1 0.1 1.3 1 0 0 1 1 1 1 Lysine methyltransferase CMAS PF02353.20 OAG41883.1 - 0.012 14.9 0.0 0.017 14.5 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.11 OAG41883.1 - 0.094 11.6 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_18 PF12847.7 OAG41883.1 - 0.13 12.2 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.6 OAG41883.1 - 0.17 11.9 0.1 0.25 11.3 0.1 1.2 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.20 OAG41883.1 - 0.26 10.3 0.0 0.32 10.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Zn_clus PF00172.18 OAG41884.1 - 8.7e-05 22.6 10.6 0.00017 21.6 10.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 OAG41885.1 - 2.3e-09 36.7 34.4 0.00013 21.1 20.3 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.16 OAG41885.1 - 5.1e-08 32.8 5.9 5.1e-08 32.8 5.9 2.6 3 1 0 3 3 3 1 Ion channel regulatory protein UNC-93 DUF3487 PF11990.8 OAG41885.1 - 0.92 9.4 4.5 0.95 9.4 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3487) Peptidase_M20 PF01546.28 OAG41886.1 - 2.2e-24 86.3 0.1 3.8e-24 85.5 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 OAG41886.1 - 5.9e-05 22.9 0.0 0.00011 22.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 OAG41886.1 - 0.029 14.0 0.1 0.085 12.5 0.0 1.8 2 0 0 2 2 2 0 Peptidase family M28 BET PF17035.5 OAG41886.1 - 0.051 13.8 0.0 0.089 13.0 0.0 1.3 1 0 0 1 1 1 0 Bromodomain extra-terminal - transcription regulation Fungal_trans PF04082.18 OAG41887.1 - 1.2e-06 27.7 0.3 2.1e-06 27.0 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Imm2 PF14426.6 OAG41887.1 - 0.033 14.2 1.2 0.075 13.1 0.0 2.1 2 0 0 2 2 2 0 Immunity protein Imm2 Methyltransf_2 PF00891.18 OAG41888.1 - 6.6e-25 87.6 0.0 9.3e-25 87.2 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation PF08100.11 OAG41888.1 - 4.9e-07 29.7 0.1 0.00058 19.8 0.1 2.7 2 0 0 2 2 2 2 Dimerisation domain Dimerisation2 PF16864.5 OAG41888.1 - 5.8e-05 23.0 0.1 0.00019 21.4 0.1 1.9 2 0 0 2 2 2 1 Dimerisation domain Frataxin_Cyay PF01491.16 OAG41889.1 - 9.7e-37 125.3 0.0 1.4e-36 124.8 0.0 1.2 1 0 0 1 1 1 1 Frataxin-like domain Ribosomal_L30 PF00327.20 OAG41889.1 - 5.7e-16 58.1 0.2 8.6e-16 57.6 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e adh_short PF00106.25 OAG41891.1 - 7e-14 51.7 0.0 8.9e-14 51.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG41891.1 - 9.1e-08 31.9 0.0 1.1e-07 31.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG41891.1 - 5.1e-05 23.2 0.0 8.3e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 OAG41891.1 - 0.12 12.3 0.1 0.16 11.8 0.1 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NUDIX PF00293.28 OAG41892.1 - 1.7e-07 31.3 0.1 5.7e-07 29.6 0.0 1.6 1 1 1 2 2 2 1 NUDIX domain DHH PF01368.20 OAG41893.1 - 4.6e-07 30.0 0.1 2.1e-06 27.9 0.0 2.1 2 0 0 2 2 2 1 DHH family GOLGA2L5 PF15070.6 OAG41894.1 - 0.0076 15.0 20.0 0.01 14.5 20.0 1.2 1 0 0 1 1 1 1 Putative golgin subfamily A member 2-like protein 5 Cnn_1N PF07989.11 OAG41894.1 - 0.013 15.7 4.8 0.013 15.7 4.8 3.5 1 1 2 3 3 3 0 Centrosomin N-terminal motif 1 DnaB_C PF03796.15 OAG41894.1 - 0.27 10.5 7.5 0.37 10.1 7.5 1.2 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain YjbH PF06082.11 OAG41894.1 - 1.2 7.9 8.6 1.4 7.6 8.6 1.1 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH OrfB_IS605 PF01385.19 OAG41894.1 - 2.8 8.2 12.4 0.15 12.3 4.2 2.6 2 1 1 3 3 3 0 Probable transposase APG6_N PF17675.1 OAG41894.1 - 3.5 8.2 24.9 2.6 8.6 9.2 2.2 2 0 0 2 2 2 0 Apg6 coiled-coil region BRE1 PF08647.11 OAG41894.1 - 4 7.6 26.1 1.2 9.3 11.2 2.5 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase ZapB PF06005.12 OAG41894.1 - 7.2 7.1 32.3 5.2 7.6 13.0 4.0 1 1 2 3 3 3 0 Cell division protein ZapB bZIP_1 PF00170.21 OAG41894.1 - 8.6 6.5 19.0 1 9.5 3.1 3.6 2 1 1 3 3 3 0 bZIP transcription factor DJ-1_PfpI PF01965.24 OAG41895.1 - 1.1e-14 54.6 0.1 1.9e-14 53.8 0.1 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 OAG41895.1 - 0.00027 20.7 0.0 0.00047 19.9 0.0 1.4 1 0 0 1 1 1 1 ThiJ/PfpI family-like SNO PF01174.19 OAG41895.1 - 0.1 12.4 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 SNO glutamine amidotransferase family zf-C3HC4 PF00097.25 OAG41896.1 - 4.1e-07 29.8 7.4 8.2e-07 28.8 7.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OAG41896.1 - 2e-06 27.5 5.9 4.3e-06 26.5 5.9 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAG41896.1 - 2.4e-06 27.5 3.4 2.4e-06 27.5 3.4 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OAG41896.1 - 5.1e-06 26.2 6.7 1.6e-05 24.7 2.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAG41896.1 - 8.3e-06 26.0 7.5 1.9e-05 24.9 7.5 1.6 1 1 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 OAG41896.1 - 1.2e-05 25.2 3.9 2.9e-05 23.9 3.9 1.6 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 OAG41896.1 - 4.2e-05 23.6 6.0 0.00024 21.2 6.3 2.0 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 OAG41896.1 - 0.0048 16.7 7.6 0.028 14.3 7.7 2.2 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 OAG41896.1 - 1.1 9.6 5.8 3.5 8.0 5.8 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-ribbon_3 PF13248.6 OAG41896.1 - 3.5 7.2 5.0 9.7 5.8 0.9 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-RING_10 PF16685.5 OAG41896.1 - 3.8 7.7 5.5 0.82 9.9 2.0 1.6 2 0 0 2 2 2 0 zinc RING finger of MSL2 UCH PF00443.29 OAG41897.1 - 1.3e-46 159.2 0.0 2.4e-46 158.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OAG41897.1 - 5.7e-11 42.6 0.0 1.4e-05 24.8 0.0 2.4 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase BTB PF00651.31 OAG41898.1 - 2.5e-06 27.7 0.0 4.8e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain DsrC PF04358.13 OAG41898.1 - 0.041 14.4 0.4 0.26 11.8 0.1 2.2 1 1 1 2 2 2 0 DsrC like protein DUF5491 PF17595.2 OAG41898.1 - 0.057 13.7 0.1 0.2 12.0 0.1 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5491) Phage_TAC_5 PF08890.11 OAG41898.1 - 0.1 12.6 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Phage XkdN-like tail assembly chaperone protein, TAC ABC2_membrane PF01061.24 OAG41899.1 - 5.5e-79 264.5 61.7 2.4e-40 138.2 17.6 2.6 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 OAG41899.1 - 2.8e-34 118.6 0.0 1.7e-16 61.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 OAG41899.1 - 9.3e-25 86.4 10.9 5.1e-23 80.8 0.0 3.6 4 0 0 4 4 2 2 CDR ABC transporter ABC_trans_N PF14510.6 OAG41899.1 - 5.4e-15 55.8 0.1 2.1e-14 53.9 0.1 2.1 1 0 0 1 1 1 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 OAG41899.1 - 1.1e-06 28.1 15.8 1.1e-06 28.1 15.8 2.5 2 1 0 2 2 2 1 ABC-2 family transporter protein AAA_21 PF13304.6 OAG41899.1 - 1.4e-05 25.1 0.0 0.23 11.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 OAG41899.1 - 2.7e-05 24.6 0.2 0.014 15.8 0.1 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 OAG41899.1 - 0.0002 21.9 0.9 0.049 14.2 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_33 PF13671.6 OAG41899.1 - 0.00022 21.4 2.7 0.046 13.9 0.0 2.9 3 0 0 3 3 2 2 AAA domain RsgA_GTPase PF03193.16 OAG41899.1 - 0.00033 20.6 0.2 0.0012 18.7 0.0 2.0 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 OAG41899.1 - 0.00033 20.3 0.4 0.015 15.1 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain SMC_N PF02463.19 OAG41899.1 - 0.0013 18.2 0.0 0.29 10.5 0.0 3.1 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 OAG41899.1 - 0.0017 17.9 0.2 0.034 13.7 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 OAG41899.1 - 0.0031 17.9 0.6 0.4 11.1 0.1 2.7 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 OAG41899.1 - 0.0031 17.8 0.1 0.23 11.7 0.1 2.8 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 OAG41899.1 - 0.0074 16.0 0.2 1.2 8.8 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 OAG41899.1 - 0.0087 16.3 0.4 0.53 10.6 0.1 2.8 2 1 0 2 2 2 1 AAA domain NACHT PF05729.12 OAG41899.1 - 0.03 14.2 0.3 4.8 7.1 0.2 2.5 2 0 0 2 2 2 0 NACHT domain cobW PF02492.19 OAG41899.1 - 0.046 13.3 1.5 0.51 9.9 0.4 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.6 OAG41899.1 - 0.19 12.2 2.0 0.46 11.0 0.0 2.5 3 0 0 3 3 3 0 AAA domain AAA_13 PF13166.6 OAG41899.1 - 0.39 9.3 1.8 11 4.5 0.0 3.5 4 0 0 4 4 4 0 AAA domain ABC_tran PF00005.27 OAG41900.1 - 4.5e-49 166.5 0.0 9.5e-26 90.9 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 OAG41900.1 - 1.6e-23 83.4 44.6 2.9e-14 53.0 24.5 2.5 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 OAG41900.1 - 1.8e-22 80.6 0.9 0.00013 21.9 1.0 4.6 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OAG41900.1 - 3.7e-09 36.4 1.4 9.3e-06 25.2 0.1 3.8 2 2 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 OAG41900.1 - 7.9e-09 35.1 1.5 0.00015 21.5 0.5 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 OAG41900.1 - 4.8e-08 33.8 0.7 0.0031 18.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain DUF4162 PF13732.6 OAG41900.1 - 2.3e-05 25.0 0.0 0.0069 17.1 0.0 2.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4162) AAA_27 PF13514.6 OAG41900.1 - 2.6e-05 23.9 0.3 0.22 11.1 0.1 2.4 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 OAG41900.1 - 0.00018 21.9 0.2 0.34 11.3 0.0 2.9 3 0 0 3 3 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 OAG41900.1 - 0.00026 20.9 0.1 0.78 9.6 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_15 PF13175.6 OAG41900.1 - 0.00049 19.9 0.0 0.15 11.8 0.0 3.0 3 0 0 3 3 3 1 AAA ATPase domain AAA_30 PF13604.6 OAG41900.1 - 0.00073 19.3 0.2 1.6 8.4 0.1 2.6 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 OAG41900.1 - 0.017 15.4 0.3 1.2 9.4 0.2 2.5 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 OAG41900.1 - 0.029 14.0 0.2 7.5 6.1 0.1 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Zeta_toxin PF06414.12 OAG41900.1 - 0.035 13.4 0.1 9.4 5.5 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin RNA_helicase PF00910.22 OAG41900.1 - 0.043 14.2 0.0 2.9 8.3 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_18 PF13238.6 OAG41900.1 - 0.063 13.8 0.0 24 5.5 0.0 3.4 4 0 0 4 4 3 0 AAA domain AAA_22 PF13401.6 OAG41900.1 - 0.087 13.1 0.0 15 5.9 0.0 2.9 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 OAG41900.1 - 0.095 12.1 0.5 6.1 6.2 0.1 3.0 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI EPV_E5 PF08135.11 OAG41900.1 - 0.12 12.8 2.4 0.49 10.8 2.4 2.0 1 0 0 1 1 1 0 Major transforming protein E5 family MukB PF04310.12 OAG41900.1 - 0.12 12.1 1.3 15 5.3 0.2 2.7 3 0 0 3 3 2 0 MukB N-terminal AAA PF00004.29 OAG41900.1 - 0.18 12.2 0.2 56 4.2 0.0 3.8 4 1 0 4 4 3 0 ATPase family associated with various cellular activities (AAA) G-alpha PF00503.20 OAG41900.1 - 0.19 10.8 0.0 1.1 8.3 0.0 2.0 2 0 0 2 2 2 0 G-protein alpha subunit SbcCD_C PF13558.6 OAG41900.1 - 0.31 11.3 8.7 4.1 7.7 0.0 4.5 4 2 0 4 4 2 0 Putative exonuclease SbcCD, C subunit p450 PF00067.22 OAG41901.1 - 1.7e-42 145.8 0.2 5.7e-27 94.6 0.0 2.4 2 1 0 2 2 2 2 Cytochrome P450 Kelch_5 PF13854.6 OAG41902.1 - 1.4e-10 40.9 0.5 5e-07 29.6 0.1 3.2 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.6 OAG41902.1 - 0.0013 18.9 3.6 5.6 7.4 0.0 5.5 5 1 0 5 5 5 1 Kelch motif Herpes_gE PF02480.16 OAG41902.1 - 0.0059 15.4 0.0 0.0083 14.9 0.0 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Kelch_4 PF13418.6 OAG41902.1 - 0.013 15.5 5.0 5.9 7.0 0.0 5.4 4 1 1 5 5 5 0 Galactose oxidase, central domain Kelch_2 PF07646.15 OAG41902.1 - 0.015 15.2 1.2 3.7 7.7 0.0 4.2 5 0 0 5 5 5 0 Kelch motif DUF4381 PF14316.6 OAG41902.1 - 0.1 12.9 0.2 0.41 10.9 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Kelch_1 PF01344.25 OAG41902.1 - 0.18 11.4 1.7 9.8 5.9 0.0 3.8 4 0 0 4 4 4 0 Kelch motif BatA PF07584.11 OAG41902.1 - 0.18 12.2 0.2 0.43 11.0 0.2 1.6 1 0 0 1 1 1 0 Aerotolerance regulator N-terminal SKG6 PF08693.10 OAG41902.1 - 0.23 10.9 2.3 0.57 9.6 2.3 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Kelch_3 PF13415.6 OAG41902.1 - 0.3 11.4 15.4 9.3 6.7 0.1 5.8 6 0 0 6 6 6 0 Galactose oxidase, central domain Scramblase PF03803.15 OAG41903.1 - 9.1e-52 175.5 0.0 5.6e-28 97.8 0.0 2.9 2 1 0 2 2 2 2 Scramblase AA_permease PF00324.21 OAG41904.1 - 1.5e-124 416.3 32.5 1.8e-124 416.0 32.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAG41904.1 - 2.2e-37 128.9 35.8 3e-37 128.5 35.8 1.2 1 0 0 1 1 1 1 Amino acid permease DNA_ligase_A_M PF01068.21 OAG41905.1 - 1.1e-24 87.2 0.0 2.1e-24 86.3 0.0 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 OAG41905.1 - 6.3e-16 59.2 0.0 1.7e-15 57.8 0.0 1.8 2 0 0 2 2 2 1 DNA ligase N terminus TRI12 PF06609.13 OAG41906.1 - 2.1e-32 112.3 28.6 2.6e-32 112.1 28.6 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG41906.1 - 7e-14 51.5 64.8 1.2e-12 47.5 59.2 3.9 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG41906.1 - 3e-08 33.0 16.4 3e-08 33.0 16.4 2.9 3 1 0 3 3 3 2 Sugar (and other) transporter DAO PF01266.24 OAG41907.1 - 1.1e-32 114.0 0.1 1.3e-32 113.8 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase ThiF PF00899.21 OAG41907.1 - 3.8e-05 23.2 0.7 0.00016 21.1 0.0 2.1 3 0 0 3 3 3 1 ThiF family Pyr_redox_2 PF07992.14 OAG41907.1 - 0.00083 18.7 0.0 0.14 11.4 0.0 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG41907.1 - 0.00096 19.3 0.0 0.0032 17.7 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.20 OAG41907.1 - 0.0095 16.0 0.0 0.017 15.2 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase GIDA PF01134.22 OAG41907.1 - 0.012 14.7 0.0 2.8 6.9 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_7 PF13241.6 OAG41907.1 - 0.014 15.9 0.0 0.027 14.9 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding FAD_binding_3 PF01494.19 OAG41907.1 - 0.029 13.6 0.0 0.048 12.9 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 OAG41907.1 - 0.037 14.6 0.0 0.24 12.0 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TadE PF07811.12 OAG41907.1 - 0.098 12.9 0.3 0.098 12.9 0.3 2.1 3 0 0 3 3 3 0 TadE-like protein EntA_Immun PF08951.10 OAG41907.1 - 0.17 12.2 0.0 0.29 11.5 0.0 1.3 1 0 0 1 1 1 0 Enterocin A Immunity Fungal_trans_2 PF11951.8 OAG41908.1 - 1.1e-67 228.5 2.9 1.4e-67 228.2 2.9 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG41908.1 - 6.1e-07 29.5 8.0 1.2e-06 28.5 8.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 OAG41909.1 - 4.7e-27 94.8 28.1 4.7e-27 94.8 28.1 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily ATPase_gene1 PF09527.10 OAG41909.1 - 0.0043 17.2 0.8 0.0043 17.2 0.8 4.4 6 0 0 6 6 6 1 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter NADHdh-2_N PF12155.8 OAG41909.1 - 0.046 14.1 0.1 0.15 12.5 0.1 1.8 1 0 0 1 1 1 0 NADH dehydrogenase subunit 2 N-terminal Pkinase PF00069.25 OAG41910.1 - 1.9e-65 220.9 0.0 3.2e-65 220.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG41910.1 - 4e-46 157.4 0.0 1.6e-45 155.4 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAG41910.1 - 8.8e-07 28.0 1.9 5.5e-05 22.1 0.0 2.4 2 0 0 2 2 2 2 Fungal protein kinase Kinase-like PF14531.6 OAG41910.1 - 0.0021 17.5 0.0 0.013 14.9 0.0 2.1 2 0 0 2 2 2 1 Kinase-like ABC1 PF03109.16 OAG41910.1 - 0.062 13.5 0.0 0.15 12.2 0.0 1.7 1 0 0 1 1 1 0 ABC1 family DUF4048 PF13257.6 OAG41911.1 - 9.7e-41 140.3 16.8 3e-29 102.6 3.6 2.7 1 1 1 2 2 2 2 Domain of unknown function (DUF4048) Bap31_Bap29_C PF18035.1 OAG41911.1 - 0.0066 16.4 1.5 0.018 15.1 1.5 1.8 1 0 0 1 1 1 1 Bap31/Bap29 cytoplasmic coiled-coil domain Glyco_hydro_76 PF03663.14 OAG41912.1 - 2.6e-146 487.9 23.2 3e-146 487.7 23.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 OAG41912.1 - 0.069 12.2 9.5 0.092 11.8 2.3 2.8 1 1 0 2 2 2 0 Glycosyl Hydrolase Family 88 TrkH PF02386.16 OAG41913.1 - 1.8e-149 498.4 9.8 5.6e-149 496.8 6.0 2.1 2 0 0 2 2 2 2 Cation transport protein DUF2358 PF10184.9 OAG41914.1 - 0.15 12.3 0.0 0.2 11.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2358) MFS_1 PF07690.16 OAG41915.1 - 2.5e-39 135.2 42.9 2.5e-39 135.2 42.9 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG41915.1 - 0.0016 17.4 22.3 0.0056 15.6 15.7 3.4 2 1 1 3 3 3 2 Sugar (and other) transporter DUF1749 PF08538.10 OAG41916.1 - 1.1e-67 228.3 0.0 1.3e-67 228.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.7 OAG41916.1 - 8e-05 23.3 1.6 0.00011 22.9 0.9 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG41916.1 - 0.00056 19.2 0.1 0.0028 16.9 0.1 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 OAG41916.1 - 0.013 15.4 0.0 0.039 13.8 0.0 1.8 2 0 0 2 2 2 0 Serine hydrolase DUF900 PF05990.12 OAG41916.1 - 0.045 13.3 0.0 0.069 12.6 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) LIDHydrolase PF10230.9 OAG41916.1 - 0.056 13.0 0.0 0.31 10.6 0.0 2.1 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase LSDAT_euk PF18139.1 OAG41916.1 - 0.12 11.8 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 SLOG in TRPM CPP1-like PF11833.8 OAG41917.1 - 3.3 7.3 4.9 5.6 6.6 0.4 2.3 1 1 1 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like DUF2012 PF09430.10 OAG41918.1 - 5.4e-25 87.9 0.0 7.4e-25 87.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) EAV_GS PF01309.18 OAG41918.1 - 0.02 14.5 0.0 0.031 13.9 0.0 1.4 1 0 0 1 1 1 0 Equine arteritis virus small envelope glycoprotein Beta-lactamase PF00144.24 OAG41919.1 - 2.7e-40 138.6 2.9 1e-39 136.7 2.9 1.8 1 1 0 1 1 1 1 Beta-lactamase Glutaminase PF04960.15 OAG41919.1 - 0.18 10.9 0.0 0.42 9.8 0.0 1.5 2 0 0 2 2 2 0 Glutaminase Fungal_trans PF04082.18 OAG41920.1 - 2.2e-06 26.9 0.1 3.5e-05 23.0 0.1 2.2 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG41920.1 - 3.3e-05 23.9 7.0 7.6e-05 22.8 7.0 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aminotran_3 PF00202.21 OAG41921.1 - 1.7e-86 290.4 0.0 2.1e-86 290.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III WW PF00397.26 OAG41922.1 - 2.2e-10 40.4 2.8 4.8e-10 39.3 2.8 1.6 1 0 0 1 1 1 1 WW domain WD40 PF00400.32 OAG41923.1 - 0.0012 19.6 0.6 0.0012 19.6 0.6 3.0 3 0 0 3 3 3 1 WD domain, G-beta repeat ADH_N PF08240.12 OAG41924.1 - 9.1e-26 89.9 3.8 9.1e-26 89.9 3.8 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG41924.1 - 1.1e-06 28.7 0.0 0.00034 20.6 0.0 2.5 2 0 0 2 2 2 2 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 OAG41924.1 - 0.00026 20.9 0.4 0.00026 20.9 0.4 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-associated HydF_tetramer PF18133.1 OAG41924.1 - 0.017 14.8 0.7 0.047 13.4 0.7 1.7 1 0 0 1 1 1 0 Hydrogen maturase F tetramerization domain Neuroparsin PF07327.11 OAG41924.1 - 0.036 14.5 1.7 0.084 13.3 1.7 1.6 1 0 0 1 1 1 0 Neuroparsin Transp_cyt_pur PF02133.15 OAG41925.1 - 2.1e-90 303.7 37.8 2.6e-90 303.3 37.8 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF4538 PF15061.6 OAG41925.1 - 0.14 11.9 0.0 0.56 10.0 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4538) Amidohydro_1 PF01979.20 OAG41926.1 - 3.5e-28 98.9 0.0 4.5e-28 98.5 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 OAG41926.1 - 1.3e-19 71.0 0.9 1.5e-09 37.9 0.0 2.5 3 0 0 3 3 3 2 Amidohydrolase family Urease_alpha PF00449.20 OAG41926.1 - 0.044 14.1 0.0 0.099 13.0 0.0 1.6 1 0 0 1 1 1 0 Urease alpha-subunit, N-terminal domain Ank_4 PF13637.6 OAG41927.1 - 0.0009 19.8 0.2 0.01 16.4 0.0 2.6 2 1 0 3 3 3 1 Ankyrin repeats (many copies) Catalase PF00199.19 OAG41928.1 - 4.9e-30 104.9 0.0 6.5e-30 104.5 0.0 1.1 1 0 0 1 1 1 1 Catalase Asp_Glu_race PF01177.22 OAG41929.1 - 3.8e-12 46.5 0.1 5.5e-12 46.0 0.1 1.2 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase Amdase PF17645.1 OAG41929.1 - 0.00022 20.9 0.2 0.00038 20.2 0.2 1.4 1 0 0 1 1 1 1 Arylmalonate decarboxylase CN_hydrolase PF00795.22 OAG41930.1 - 4.6e-38 131.1 0.0 7.2e-38 130.4 0.0 1.3 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase p450 PF00067.22 OAG41931.1 - 3.3e-49 167.9 0.0 7.2e-49 166.8 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 F-box PF00646.33 OAG41932.1 - 1.3e-06 28.1 0.2 3.5e-06 26.8 0.2 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 OAG41932.1 - 0.00031 20.6 0.4 0.00068 19.5 0.4 1.6 1 0 0 1 1 1 1 F-box-like DUF1100 PF06500.11 OAG41933.1 - 4.9e-15 55.3 0.0 8e-15 54.5 0.0 1.3 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF1100) Peptidase_S15 PF02129.18 OAG41933.1 - 4.5e-10 39.6 0.0 7e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.20 OAG41933.1 - 2.4e-09 37.2 0.1 1.2e-07 31.6 0.1 2.1 1 1 0 2 2 2 1 alpha/beta hydrolase fold Esterase PF00756.20 OAG41933.1 - 9.5e-08 32.0 0.0 5.1e-07 29.6 0.0 2.0 1 1 0 1 1 1 1 Putative esterase Abhydrolase_6 PF12697.7 OAG41933.1 - 1.1e-07 32.7 0.0 1.6e-07 32.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 OAG41933.1 - 1.2e-06 28.1 0.0 3.1e-06 26.8 0.0 1.8 1 1 0 1 1 1 1 Prolyl oligopeptidase family BAAT_C PF08840.11 OAG41933.1 - 3e-05 24.1 0.0 9.3e-05 22.4 0.0 1.7 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Hydrolase_4 PF12146.8 OAG41933.1 - 4.4e-05 22.9 0.0 7.9e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 OAG41933.1 - 0.0016 18.3 0.0 0.003 17.4 0.0 1.4 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_7 PF12715.7 OAG41933.1 - 0.0071 15.6 0.0 0.12 11.6 0.0 2.1 2 0 0 2 2 2 1 Abhydrolase family DLH PF01738.18 OAG41933.1 - 0.0085 15.7 0.0 0.032 13.8 0.0 1.9 1 1 0 1 1 1 1 Dienelactone hydrolase family USP8_dimer PF08969.11 OAG41933.1 - 0.062 13.5 0.2 0.11 12.6 0.2 1.4 1 0 0 1 1 1 0 USP8 dimerisation domain Abhydrolase_3 PF07859.13 OAG41933.1 - 0.07 13.0 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold UPF0227 PF05728.12 OAG41933.1 - 0.18 11.7 0.0 0.63 10.0 0.0 1.9 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0227) MIT PF04212.18 OAG41933.1 - 0.21 11.7 1.0 0.43 10.7 1.0 1.4 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain Peptidase_S58 PF03576.14 OAG41933.1 - 0.28 10.7 0.0 0.38 10.2 0.0 1.1 1 0 0 1 1 1 0 Peptidase family S58 Clr5 PF14420.6 OAG41934.1 - 5.7e-20 71.3 0.5 3.3e-19 68.9 0.7 2.1 2 0 0 2 2 2 1 Clr5 domain TPR_12 PF13424.6 OAG41934.1 - 5.4e-12 45.8 3.6 1.7e-05 25.0 0.5 4.2 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.6 OAG41934.1 - 7.4e-07 28.9 0.1 0.00079 19.2 0.0 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF3856 PF12968.7 OAG41934.1 - 0.00082 19.5 0.4 0.089 12.9 0.3 2.6 2 0 0 2 2 2 1 Domain of Unknown Function (DUF3856) TPR_19 PF14559.6 OAG41934.1 - 0.011 16.2 0.2 1.1 9.8 0.1 2.9 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 OAG41934.1 - 0.02 15.0 0.4 3 8.2 0.2 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 OAG41934.1 - 0.077 13.7 4.4 5.9 7.6 0.1 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 OAG41934.1 - 0.16 12.3 0.1 21 5.7 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 OAG41934.1 - 0.26 11.2 3.7 0.52 10.2 0.2 3.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Sigma70_r4 PF04545.16 OAG41934.1 - 0.34 10.5 1.5 1.6 8.3 0.1 2.4 2 0 0 2 2 2 0 Sigma-70, region 4 Cupin_2 PF07883.11 OAG41935.1 - 5.8e-08 32.3 0.0 1.2e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 OAG41935.1 - 0.098 12.4 0.1 0.37 10.5 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF861) BBS2_Mid PF14783.6 OAG41935.1 - 0.15 12.1 0.1 1.1 9.3 0.0 2.1 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region MIP PF00230.20 OAG41936.1 - 1.7e-41 142.4 8.8 2.2e-41 142.0 8.8 1.1 1 0 0 1 1 1 1 Major intrinsic protein UPF0029 PF01205.19 OAG41937.1 - 2.2e-34 117.9 0.0 4.2e-34 117.0 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.22 OAG41937.1 - 1.2e-07 32.1 0.0 3.5e-07 30.5 0.0 1.7 1 1 0 1 1 1 1 RWD domain UQ_con PF00179.26 OAG41937.1 - 0.052 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-conjugating enzyme NUP PF06516.11 OAG41938.1 - 2e-136 454.3 0.0 2.4e-136 454.0 0.0 1.0 1 0 0 1 1 1 1 Purine nucleoside permease (NUP) His_Phos_1 PF00300.22 OAG41939.1 - 7.7e-34 117.1 0.4 1e-33 116.7 0.4 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) NmrA PF05368.13 OAG41940.1 - 6.2e-68 228.8 0.0 2.3e-62 210.6 0.0 2.1 1 1 1 2 2 2 2 NmrA-like family NAD_binding_10 PF13460.6 OAG41940.1 - 1.3e-07 31.7 0.0 2.1e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Asparaginase PF00710.20 OAG41941.1 - 8e-62 208.2 0.0 1.3e-61 207.5 0.0 1.3 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 OAG41941.1 - 1.5e-28 99.3 0.1 3.2e-28 98.2 0.1 1.6 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain Ank_2 PF12796.7 OAG41941.1 - 4.2e-12 46.5 2.6 5.9e-07 30.0 0.3 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAG41941.1 - 3.1e-07 30.8 0.2 1.9e-05 25.1 0.1 2.6 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG41941.1 - 1.3e-05 25.2 3.1 0.14 12.8 0.1 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 OAG41941.1 - 2.6e-05 24.4 0.8 6.6e-05 23.1 0.8 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 OAG41941.1 - 0.00025 21.3 4.9 0.007 16.8 1.1 3.1 2 0 0 2 2 2 1 Ankyrin repeat DUF1843 PF08898.10 OAG41941.1 - 0.075 13.5 0.1 0.32 11.5 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) DMA PF03474.14 OAG41941.1 - 0.15 11.6 0.0 1.1 8.9 0.0 2.2 2 0 0 2 2 2 0 DMRTA motif DUF1996 PF09362.10 OAG41942.1 - 4e-76 256.1 0.1 6e-76 255.5 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Antimicrobial12 PF08107.11 OAG41942.1 - 0.14 12.0 0.4 0.27 11.0 0.4 1.4 1 0 0 1 1 1 0 Pleurocidin family F-box PF00646.33 OAG41944.1 - 0.0039 17.0 0.3 0.029 14.3 0.1 2.5 2 1 1 3 3 3 1 F-box domain PRANC PF09372.10 OAG41944.1 - 0.0085 16.4 0.0 0.019 15.3 0.0 1.5 1 0 0 1 1 1 1 PRANC domain TMEM51 PF15345.6 OAG41945.1 - 0.00036 20.4 0.0 0.00062 19.7 0.0 1.4 1 1 0 2 2 2 1 Transmembrane protein 51 Ninjurin PF04923.12 OAG41945.1 - 0.15 12.0 0.0 0.17 11.8 0.0 1.1 1 0 0 1 1 1 0 Ninjurin DUF3328 PF11807.8 OAG41945.1 - 0.16 11.7 0.0 0.19 11.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) Git3 PF11710.8 OAG41945.1 - 0.21 11.4 1.5 0.27 11.0 1.5 1.1 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 Beta-lactamase PF00144.24 OAG41946.1 - 8.3e-31 107.4 0.1 1.3e-30 106.7 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase Adap_comp_sub PF00928.21 OAG41948.1 - 2.3e-21 76.3 0.0 3.7e-21 75.7 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 OAG41948.1 - 1.2e-08 35.0 0.0 1.9e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain RPM2 PF08579.11 OAG41948.1 - 0.0087 16.5 0.2 0.017 15.5 0.2 1.4 1 0 0 1 1 1 1 Mitochondrial ribonuclease P subunit (RPM2) ChiW_Ig_like PF18683.1 OAG41948.1 - 0.45 10.8 5.9 4 7.7 0.2 3.1 2 1 1 3 3 3 0 Chitinase W immunoglobulin-like domain Cellulase PF00150.18 OAG41949.1 - 4.4e-20 72.3 0.1 4.4e-20 72.3 0.1 1.4 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) AAA_23 PF13476.6 OAG41950.1 - 8.7e-36 124.3 6.6 8.7e-36 124.3 6.6 9.0 3 1 2 5 5 2 1 AAA domain AAA_15 PF13175.6 OAG41950.1 - 8.1e-12 45.5 28.3 4.1e-10 39.9 10.4 4.9 2 2 2 4 4 2 2 AAA ATPase domain SMC_N PF02463.19 OAG41950.1 - 4.1e-11 42.7 39.9 7.9e-10 38.5 0.1 3.3 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 OAG41950.1 - 1.1e-08 35.3 12.1 3.4e-05 23.8 0.0 3.4 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 OAG41950.1 - 1.4e-07 31.6 0.0 4.9e-07 29.9 0.0 2.0 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 OAG41950.1 - 1.6e-05 24.5 0.0 3.6e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Cep57_MT_bd PF06657.13 OAG41950.1 - 0.0065 16.9 2.0 0.0065 16.9 2.0 10.2 7 2 5 12 12 11 1 Centrosome microtubule-binding domain of Cep57 NPV_P10 PF05531.12 OAG41950.1 - 0.0073 16.8 2.9 0.0073 16.8 2.9 8.7 8 2 3 12 12 11 1 Nucleopolyhedrovirus P10 protein ABC_tran PF00005.27 OAG41950.1 - 0.028 14.9 0.0 0.028 14.9 0.0 7.2 3 2 1 4 4 2 0 ABC transporter AAA_16 PF13191.6 OAG41950.1 - 0.073 13.4 0.0 0.073 13.4 0.0 6.3 3 1 3 7 7 5 0 AAA ATPase domain Sulfotransfer_4 PF17784.1 OAG41950.1 - 0.5 10.2 4.8 0.92 9.3 2.0 2.9 2 0 0 2 2 2 0 Sulfotransferase domain GATA PF00320.27 OAG41951.1 - 4.5e-16 58.2 6.1 8.1e-16 57.3 6.1 1.4 1 0 0 1 1 1 1 GATA zinc finger PAS_3 PF08447.12 OAG41951.1 - 9.9e-15 54.6 0.0 1.8e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 OAG41951.1 - 8.2e-12 45.1 0.0 1.5e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 OAG41951.1 - 1.8e-10 41.0 0.0 3.3e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 OAG41951.1 - 2.5e-10 40.5 0.0 5.1e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 PAS domain PAS_11 PF14598.6 OAG41951.1 - 3.5e-05 23.9 0.0 6.4e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 PAS domain PAS_8 PF13188.7 OAG41951.1 - 0.0037 17.3 0.0 0.0081 16.2 0.0 1.5 1 0 0 1 1 1 1 PAS domain Zn-ribbon_8 PF09723.10 OAG41951.1 - 0.01 15.9 0.2 0.02 15.0 0.2 1.5 1 0 0 1 1 1 0 Zinc ribbon domain TF_Zn_Ribbon PF08271.12 OAG41951.1 - 0.17 11.4 0.4 1 8.9 0.1 2.2 2 0 0 2 2 2 0 TFIIB zinc-binding PPP4R2 PF09184.11 OAG41952.1 - 1.1e-08 35.1 3.9 2e-08 34.2 0.0 2.7 2 1 0 2 2 2 1 PPP4R2 Fungal_trans PF04082.18 OAG41953.1 - 5.9e-21 74.7 0.5 9.7e-21 74.0 0.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pox_A_type_inc PF04508.12 OAG41953.1 - 0.054 13.4 0.0 0.17 11.8 0.0 1.9 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat MFS_1 PF07690.16 OAG41954.1 - 8.9e-27 93.9 23.6 8.9e-27 93.9 23.6 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily CD47 PF04549.14 OAG41954.1 - 0.045 13.9 0.7 0.045 13.9 0.7 3.8 3 1 1 5 5 5 0 CD47 transmembrane region SnoaL PF07366.12 OAG41955.1 - 2.1e-23 82.5 0.1 2.6e-23 82.2 0.1 1.1 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 OAG41955.1 - 3.9e-14 53.1 0.4 5.1e-14 52.7 0.4 1.2 1 0 0 1 1 1 1 SnoaL-like domain CN_hydrolase PF00795.22 OAG41956.1 - 4.6e-43 147.5 0.0 6.2e-43 147.0 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase RraA-like PF03737.15 OAG41957.1 - 1.5e-21 77.1 0.0 2.1e-21 76.6 0.0 1.1 1 0 0 1 1 1 1 Aldolase/RraA SesA PF17107.5 OAG41959.1 - 5.2e-12 46.0 0.0 6.6e-12 45.7 0.0 1.1 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases Cytochrom_B558a PF05038.13 OAG41961.1 - 9 5.8 5.7 16 5.0 5.7 1.3 1 0 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit Glyco_hydro_31 PF01055.26 OAG41962.1 - 9.6e-151 502.9 4.3 1.3e-150 502.5 4.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 OAG41962.1 - 6.4e-32 110.2 0.0 1.3e-31 109.1 0.0 1.6 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 OAG41962.1 - 0.0025 18.1 0.2 0.0025 18.1 0.2 2.7 3 0 0 3 3 3 1 Galactose mutarotase-like Pkinase PF00069.25 OAG41963.1 - 1e-64 218.5 0.0 2.5e-64 217.2 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG41963.1 - 3.4e-36 124.9 0.0 3e-30 105.4 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 OAG41963.1 - 6.2e-07 29.0 0.0 0.0012 18.2 0.0 2.3 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 OAG41963.1 - 0.00016 21.7 0.0 0.00048 20.1 0.0 1.8 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OAG41963.1 - 0.0091 15.0 0.1 0.014 14.4 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 OAG41963.1 - 0.032 13.8 0.0 0.064 12.8 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 OAG41963.1 - 0.032 13.6 0.0 0.059 12.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Senescence PF06911.12 OAG41964.1 - 9.4e-56 189.0 6.0 1.5e-55 188.4 6.0 1.3 1 0 0 1 1 1 1 Senescence-associated protein Acyl-CoA_dh_1 PF00441.24 OAG41965.1 - 7.2e-40 136.6 5.2 1.1e-39 136.0 5.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 OAG41965.1 - 8.3e-31 107.0 2.1 9.3e-31 106.8 0.2 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 OAG41965.1 - 6.9e-24 83.9 0.1 2.2e-23 82.2 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 OAG41965.1 - 1.4e-16 61.0 0.6 2.3e-16 60.3 0.6 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 OAG41965.1 - 0.0064 16.2 0.0 0.019 14.7 0.0 1.7 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal AgrD PF05931.11 OAG41965.1 - 0.03 14.3 0.0 0.077 13.0 0.0 1.6 1 0 0 1 1 1 0 Staphylococcal AgrD protein GWT1 PF06423.12 OAG41966.1 - 2.8e-37 128.1 0.7 2.8e-37 128.1 0.7 2.1 2 0 0 2 2 2 1 GWT1 Zn_clus PF00172.18 OAG41966.1 - 7.2e-08 32.4 9.8 1.1e-07 31.8 9.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAG41966.1 - 3.2e-06 26.4 0.3 3.2e-06 26.4 0.3 2.9 4 0 0 4 4 4 1 Fungal specific transcription factor domain DUF4818 PF16089.5 OAG41966.1 - 0.012 16.1 0.6 0.058 13.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4818) Choline_kinase PF01633.20 OAG41967.1 - 1.2e-57 194.9 0.0 4.1e-57 193.2 0.0 1.9 2 0 0 2 2 2 1 Choline/ethanolamine kinase Choline_kin_N PF04428.14 OAG41967.1 - 6.2e-17 61.0 0.0 1.6e-16 59.7 0.0 1.8 1 0 0 1 1 1 1 Choline kinase N terminus APH PF01636.23 OAG41967.1 - 0.00051 20.0 0.4 0.0014 18.6 0.4 1.8 1 0 0 1 1 1 1 Phosphotransferase enzyme family Mg_trans_NIPA PF05653.14 OAG41968.1 - 4e-103 344.6 15.3 4.7e-103 344.3 15.3 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 OAG41968.1 - 0.00019 21.6 7.3 0.00019 21.6 7.3 3.4 3 0 0 3 3 3 2 EamA-like transporter family zf-C2H2_aberr PF17017.5 OAG41969.1 - 0.00034 20.8 1.4 0.024 14.8 0.0 2.2 2 0 0 2 2 2 1 Aberrant zinc-finger zf-C2H2 PF00096.26 OAG41969.1 - 0.00043 20.6 11.8 0.13 12.8 0.5 3.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAG41969.1 - 0.0011 19.7 12.8 0.072 14.0 1.5 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OAG41969.1 - 0.024 15.1 16.3 0.041 14.3 1.0 3.4 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_jaz PF12171.8 OAG41969.1 - 0.031 14.6 3.1 0.83 10.0 0.7 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding KfrA_N PF11740.8 OAG41969.1 - 1.3 9.8 10.1 0.96 10.1 5.3 2.3 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term zf-RING_7 PF02591.15 OAG41970.1 - 0.038 14.2 1.6 2 8.7 0.6 3.0 3 0 0 3 3 3 0 C4-type zinc ribbon domain Dus PF01207.17 OAG41971.1 - 5e-45 153.9 0.0 7.6e-31 107.4 0.0 2.5 1 1 1 2 2 2 2 Dihydrouridine synthase (Dus) zf-CCCH_4 PF18044.1 OAG41971.1 - 0.00027 20.7 2.5 0.00027 20.7 2.5 3.6 4 0 0 4 4 4 2 CCCH-type zinc finger zf-CCCH PF00642.24 OAG41971.1 - 0.0038 17.1 5.0 0.41 10.6 0.4 3.3 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 OAG41971.1 - 0.032 14.3 15.5 0.17 12.0 1.9 3.2 3 0 0 3 3 3 0 Zinc finger domain Toxin_20 PF08089.11 OAG41971.1 - 0.12 12.5 2.9 0.25 11.5 2.9 1.5 1 0 0 1 1 1 0 Huwentoxin-II family GMC_oxred_N PF00732.19 OAG41972.1 - 5.2e-45 154.1 0.0 8.9e-45 153.3 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAG41972.1 - 8.6e-28 97.7 0.6 2.3e-27 96.3 0.5 1.8 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.24 OAG41972.1 - 1.2e-06 27.9 0.3 0.0022 17.2 0.1 2.3 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 OAG41972.1 - 6.7e-05 22.6 3.0 0.00027 20.6 2.7 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG41972.1 - 0.0011 18.3 0.0 0.06 12.6 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG41972.1 - 0.0027 17.9 0.1 0.0072 16.5 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 OAG41972.1 - 0.0088 15.3 0.1 0.16 11.2 0.0 2.2 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 OAG41972.1 - 0.014 14.7 0.2 0.038 13.2 0.1 1.7 2 0 0 2 2 2 0 FAD binding domain Carboxyl_trans PF01039.22 OAG41972.1 - 0.14 10.8 0.0 0.22 10.1 0.0 1.2 1 0 0 1 1 1 0 Carboxyl transferase domain Pyr_redox_3 PF13738.6 OAG41972.1 - 0.14 11.3 0.0 6.6 5.9 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Kinesin PF00225.23 OAG41973.1 - 1.4e-102 343.1 7.6 1.4e-102 343.1 7.6 1.7 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 OAG41973.1 - 4.4e-60 201.9 0.2 1.6e-59 200.2 0.2 2.0 1 0 0 1 1 1 1 Microtubule binding AAA_16 PF13191.6 OAG41973.1 - 0.22 11.9 0.0 0.22 11.9 0.0 2.8 2 1 0 2 2 2 0 AAA ATPase domain Aminotran_5 PF00266.19 OAG41974.1 - 2.1e-56 191.5 0.0 2.5e-56 191.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 OAG41974.1 - 6.7e-06 24.9 0.0 1.9e-05 23.4 0.0 1.7 3 0 0 3 3 3 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 OAG41974.1 - 2.4e-05 23.7 0.0 3.7e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Acyltransferase PF01553.21 OAG41975.1 - 0.0052 16.4 0.0 0.013 15.1 0.0 1.6 1 1 0 1 1 1 1 Acyltransferase zf-RING_6 PF14835.6 OAG41976.1 - 0.029 14.2 6.5 0.051 13.4 6.5 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Prok-RING_4 PF14447.6 OAG41976.1 - 0.68 9.8 11.7 1.2 9.0 11.7 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 OAG41976.1 - 6.2 6.8 11.8 10 6.1 11.8 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Abhydrolase_3 PF07859.13 OAG41977.1 - 4.9e-21 75.6 0.0 6.5e-21 75.2 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 OAG41977.1 - 3.4e-15 55.8 0.0 5.9e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 Steryl acetyl hydrolase CBFD_NFYB_HMF PF00808.23 OAG41978.1 - 3.5e-15 56.0 1.0 5.9e-15 55.3 1.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 OAG41978.1 - 0.00063 20.1 0.4 0.00063 20.1 0.4 2.1 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Phage_holin_3_6 PF07332.11 OAG41979.1 - 0.014 15.5 11.6 0.02 14.9 6.4 2.2 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III DUF2070 PF09843.9 OAG41979.1 - 5.4 5.2 6.8 6.6 4.9 6.8 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) RAI16-like PF10257.9 OAG41980.1 - 2e-67 227.6 0.2 3.4e-67 226.9 0.2 1.3 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein REV PF00424.18 OAG41980.1 - 0.18 11.8 1.4 1.3 9.1 0.7 2.4 1 1 1 2 2 2 0 REV protein (anti-repression trans-activator protein) A_deaminase PF00962.22 OAG41981.1 - 5.5e-53 180.4 0.0 6.4e-53 180.2 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase DUF2063 PF09836.9 OAG41981.1 - 0.0056 16.9 0.1 0.012 15.8 0.1 1.5 1 0 0 1 1 1 1 Putative DNA-binding domain Kelch_4 PF13418.6 OAG41982.1 - 2e-30 104.6 12.5 1.7e-05 24.7 0.1 6.5 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.6 OAG41982.1 - 1.6e-29 101.6 14.2 2.9e-07 30.6 0.1 6.6 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_6 PF13964.6 OAG41982.1 - 4.7e-29 99.7 7.1 2.1e-09 37.4 1.1 6.6 5 1 1 6 6 6 5 Kelch motif Kelch_1 PF01344.25 OAG41982.1 - 1e-28 98.6 1.3 1.4e-08 34.1 0.2 6.5 6 0 0 6 6 6 5 Kelch motif Kelch_5 PF13854.6 OAG41982.1 - 3.3e-28 97.2 7.8 3.8e-06 26.7 0.1 6.6 6 0 0 6 6 6 6 Kelch motif Kelch_2 PF07646.15 OAG41982.1 - 7.2e-21 73.3 5.1 1.3e-06 28.1 0.1 6.9 7 0 0 7 7 6 4 Kelch motif Fez1 PF06818.15 OAG41982.1 - 0.00089 19.8 14.1 0.00089 19.8 14.1 6.0 2 2 3 5 5 4 2 Fez1 TPR_MLP1_2 PF07926.12 OAG41982.1 - 0.0011 19.0 20.2 0.0011 19.0 20.2 7.7 5 2 4 9 9 9 3 TPR/MLP1/MLP2-like protein EzrA PF06160.12 OAG41982.1 - 0.033 12.4 59.3 0.0056 14.9 14.2 4.3 4 0 0 4 4 4 0 Septation ring formation regulator, EzrA Suppressor_APC PF11414.8 OAG41982.1 - 0.35 11.0 0.0 0.35 11.0 0.0 6.2 7 1 0 7 7 7 0 Adenomatous polyposis coli tumour suppressor protein Filament PF00038.21 OAG41982.1 - 0.76 9.3 100.2 1.1 8.8 28.6 6.9 3 2 2 5 5 5 0 Intermediate filament protein Scaffolding_pro PF11418.8 OAG41982.1 - 2.4 8.8 13.7 1.4 9.5 0.6 4.3 3 1 0 3 3 3 0 Phi29 scaffolding protein Raptor_N PF14538.6 OAG41983.1 - 1.5e-62 209.9 0.0 2.6e-62 209.1 0.0 1.4 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.32 OAG41983.1 - 9.7e-06 26.2 2.5 3.3 8.7 0.0 6.2 6 0 0 6 6 6 1 WD domain, G-beta repeat BBS2_Mid PF14783.6 OAG41983.1 - 0.0079 16.2 0.1 4.4 7.4 0.1 2.8 1 1 1 2 2 2 2 Ciliary BBSome complex subunit 2, middle region HEAT PF02985.22 OAG41983.1 - 0.18 12.1 2.5 2.1 8.8 0.0 3.8 3 0 0 3 3 3 0 HEAT repeat VWA PF00092.28 OAG41984.1 - 6.7e-05 23.2 0.0 0.00013 22.3 0.0 1.5 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 OAG41984.1 - 0.0094 16.6 0.0 0.022 15.4 0.0 1.7 1 1 0 1 1 1 1 von Willebrand factor type A domain ATG2_CAD PF13329.6 OAG41985.1 - 1.4e-36 125.6 0.1 3.8e-36 124.1 0.1 1.8 1 0 0 1 1 1 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.11 OAG41985.1 - 2.2e-30 104.8 0.9 7.4e-30 103.2 0.2 2.2 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain VPS13_C PF16909.5 OAG41985.1 - 0.024 14.4 0.0 0.056 13.2 0.0 1.6 1 0 0 1 1 1 0 Vacuolar-sorting-associated 13 protein C-terminal A_deaminase PF00962.22 OAG41986.1 - 2.3e-23 83.0 0.0 5.2e-23 81.9 0.0 1.6 1 0 0 1 1 1 1 Adenosine/AMP deaminase RSN1_TM PF13967.6 OAG41986.1 - 0.052 13.3 0.1 0.095 12.5 0.1 1.3 1 0 0 1 1 1 0 Late exocytosis, associated with Golgi transport Mt_ATP-synt_B PF05405.14 OAG41986.1 - 0.064 12.9 0.2 0.12 12.0 0.2 1.4 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) RNA_pol_3_Rpc31 PF11705.8 OAG41986.1 - 1.6 9.0 15.4 2.8 8.1 15.4 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DUF3425 PF11905.8 OAG41987.1 - 4.1e-13 49.4 0.0 1.8e-12 47.3 0.0 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 OAG41987.1 - 0.0021 18.1 10.4 0.0024 17.9 7.2 2.2 2 0 0 2 2 2 1 bZIP transcription factor CCD48 PF15799.5 OAG41987.1 - 0.15 10.3 5.1 0.23 9.8 5.1 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 48 bZIP_2 PF07716.15 OAG41987.1 - 1.8 8.7 8.9 6.8 6.9 4.5 2.4 2 0 0 2 2 2 0 Basic region leucine zipper PhyH PF05721.13 OAG41988.1 - 2e-18 67.4 0.0 3e-18 66.8 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) SCP2 PF02036.17 OAG41988.1 - 0.0031 18.0 0.0 0.0086 16.6 0.0 1.7 1 1 0 1 1 1 1 SCP-2 sterol transfer family 2OG-FeII_Oxy_5 PF13759.6 OAG41988.1 - 0.036 14.5 0.0 0.27 11.7 0.0 2.3 2 0 0 2 2 2 0 Putative 2OG-Fe(II) oxygenase Mtc PF03820.17 OAG41989.1 - 7.5e-123 409.5 0.4 8.5e-123 409.4 0.4 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier ELO PF01151.18 OAG41990.1 - 6.3e-81 271.6 9.5 8.1e-81 271.2 9.5 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family Apolipoprotein PF01442.18 OAG41990.1 - 5.4e-05 23.1 18.9 5.4e-05 23.1 18.9 2.5 1 1 1 2 2 2 1 Apolipoprotein A1/A4/E domain RGI1 PF10843.8 OAG41990.1 - 0.018 14.7 0.7 0.038 13.6 0.7 1.5 1 0 0 1 1 1 0 Respiratory growth induced protein 1 DUF842 PF05811.13 OAG41990.1 - 0.058 13.1 8.0 0.13 12.0 1.3 2.8 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF842) YtxH PF12732.7 OAG41990.1 - 0.1 13.2 40.6 1.3e+04 -3.2 0.0 5.2 2 1 0 2 2 2 0 YtxH-like protein RPE65 PF03055.15 OAG41991.1 - 7.6e-109 364.9 0.1 8.6e-109 364.8 0.1 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein BCNT PF07572.12 OAG41992.1 - 1e-23 83.2 0.9 2.6e-23 81.9 0.9 1.7 1 0 0 1 1 1 1 Bucentaur or craniofacial development Porphobil_deam PF01379.20 OAG41993.1 - 0.064 12.8 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Porphobilinogen deaminase, dipyromethane cofactor binding domain DUF641 PF04859.12 OAG41993.1 - 0.13 12.6 0.0 0.29 11.5 0.0 1.5 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) zf-C2H2 PF00096.26 OAG41994.1 - 4.2e-06 26.9 8.5 4e-05 23.8 0.6 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAG41994.1 - 0.045 14.6 6.4 0.28 12.1 0.4 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger FOXP-CC PF16159.5 OAG41994.1 - 0.18 12.5 5.1 1.2 9.9 0.5 2.5 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-C2H2_6 PF13912.6 OAG41994.1 - 3.2 7.9 6.2 1.5 8.9 0.2 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger ADH_N PF08240.12 OAG41995.1 - 1.5e-24 85.9 0.7 3.3e-24 84.9 0.7 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG41995.1 - 5.2e-22 78.2 0.1 7.7e-22 77.7 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAG41995.1 - 1.1e-07 32.9 0.0 1.8e-07 32.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 OAG41995.1 - 0.00043 19.6 0.4 0.001 18.4 0.3 1.6 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain DHHC PF01529.20 OAG41995.1 - 6 7.0 6.2 10 6.2 6.2 1.2 1 0 0 1 1 1 0 DHHC palmitoyltransferase FA_hydroxylase PF04116.13 OAG41996.1 - 5e-13 49.5 1.4 5e-13 49.5 1.4 2.2 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily Ribosomal_L6e PF01159.19 OAG41997.1 - 3.1e-38 130.7 0.4 5.6e-38 129.9 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein L6e Proteasom_Rpn13 PF04683.13 OAG41998.1 - 6.8e-22 77.8 0.0 1e-21 77.3 0.0 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor RPN13_C PF16550.5 OAG41998.1 - 3.9e-11 43.1 3.3 1.6e-09 37.9 2.0 2.8 2 1 0 2 2 2 1 UCH-binding domain Lactamase_B PF00753.27 OAG41999.1 - 2.5e-06 27.6 2.9 0.014 15.4 0.0 2.8 3 0 0 3 3 3 2 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OAG41999.1 - 0.067 12.7 0.2 0.24 10.9 0.0 2.0 2 0 0 2 2 2 0 Beta-lactamase superfamily domain GN3L_Grn1 PF08701.11 OAG42001.1 - 3.7e-25 87.8 19.1 1.1e-24 86.3 19.1 1.8 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.23 OAG42001.1 - 9.4e-17 61.1 0.0 4.9e-13 49.2 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OAG42001.1 - 1.7e-08 34.5 0.0 6.4e-08 32.7 0.0 1.8 1 1 0 1 1 1 1 RsgA GTPase FeoB_N PF02421.18 OAG42001.1 - 2.5e-06 27.1 0.0 9.6e-05 22.0 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 OAG42001.1 - 0.00016 21.3 0.0 0.087 12.4 0.0 2.6 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 OAG42001.1 - 0.0023 18.0 5.7 0.51 10.4 0.2 3.7 4 0 0 4 4 4 2 Dynamin family MeaB PF03308.16 OAG42001.1 - 0.0089 15.0 1.7 0.012 14.7 0.0 2.0 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Roc PF08477.13 OAG42001.1 - 0.028 14.7 0.0 12 6.2 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase RNA_pol_3_Rpc31 PF11705.8 OAG42001.1 - 0.073 13.3 18.4 0.15 12.3 18.4 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 AAA_18 PF13238.6 OAG42001.1 - 0.08 13.5 1.1 0.23 12.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 OAG42001.1 - 0.11 12.1 0.0 1.1 8.8 0.0 2.4 2 1 1 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AP3D1 PF06375.11 OAG42001.1 - 0.31 11.3 14.3 0.76 10.0 14.3 1.6 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 CNDH2_C PF16858.5 OAG42001.1 - 0.52 10.1 9.4 0.76 9.6 9.4 1.3 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term DUF2277 PF10041.9 OAG42001.1 - 1.2 9.5 4.8 5.5 7.4 0.0 3.3 3 1 0 3 3 3 0 Uncharacterized conserved protein (DUF2277) HAD_2 PF13419.6 OAG42002.1 - 5.2e-19 69.0 0.0 7.4e-19 68.5 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OAG42002.1 - 1.1e-07 32.4 0.2 1.7e-05 25.2 0.0 2.6 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 OAG42002.1 - 0.00058 20.3 0.0 0.0015 19.0 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OAG42002.1 - 0.00093 19.2 0.0 0.0022 18.0 0.0 1.6 1 1 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 OAG42002.1 - 0.14 12.3 0.1 1.4 9.1 0.1 2.5 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Peptidase_A4 PF01828.17 OAG42002.1 - 0.17 11.3 0.0 0.28 10.6 0.0 1.3 1 0 0 1 1 1 0 Peptidase A4 family Homeodomain PF00046.29 OAG42003.1 - 2.4e-16 59.3 3.0 7e-16 57.8 3.0 1.8 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 OAG42003.1 - 0.00049 20.0 0.4 0.00049 20.0 0.4 2.1 2 0 0 2 2 2 1 Homeobox KN domain DUF4638 PF15472.6 OAG42003.1 - 0.034 13.9 0.2 0.072 12.8 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) CorA PF01544.18 OAG42004.1 - 5e-06 26.1 0.2 5e-06 26.1 0.2 1.8 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein LapA_dom PF06305.11 OAG42004.1 - 0.01 15.6 0.0 0.023 14.5 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain TAD2 PF18521.1 OAG42004.1 - 0.011 15.7 1.7 2.6 8.2 0.2 2.6 2 0 0 2 2 2 0 Transactivation domain 2 Fungal_trans_2 PF11951.8 OAG42005.1 - 5e-31 107.9 0.5 6.5e-31 107.5 0.5 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG42005.1 - 3.1e-07 30.4 9.4 6.4e-07 29.4 9.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amino_oxidase PF01593.24 OAG42006.1 - 1.1e-54 186.4 0.0 1.7e-54 185.9 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Ribonuc_L-PSP PF01042.21 OAG42006.1 - 1.7e-16 60.3 0.0 3.3e-16 59.4 0.0 1.4 1 0 0 1 1 1 1 Endoribonuclease L-PSP NAD_binding_8 PF13450.6 OAG42006.1 - 4.3e-13 49.3 0.2 3.1e-12 46.5 0.1 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 OAG42006.1 - 3.9e-07 29.8 0.9 6.8e-07 29.0 0.3 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.24 OAG42006.1 - 7.8e-07 29.0 0.2 5.2e-06 26.3 0.2 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OAG42006.1 - 3.5e-06 26.4 0.4 6.3e-06 25.5 0.4 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 OAG42006.1 - 6.5e-05 21.8 0.1 0.0024 16.6 0.1 2.2 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 OAG42006.1 - 7e-05 22.1 0.9 9e-05 21.7 0.1 1.5 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 OAG42006.1 - 0.0003 20.1 0.2 0.00061 19.1 0.1 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAG42006.1 - 0.00033 20.0 0.1 0.00057 19.2 0.1 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 OAG42006.1 - 0.0011 18.2 0.2 0.0018 17.6 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 OAG42006.1 - 0.0022 17.3 0.0 0.053 12.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAG42006.1 - 0.0031 18.0 0.0 0.0084 16.7 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OAG42006.1 - 0.0032 16.6 0.0 0.095 11.7 0.1 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 OAG42006.1 - 0.02 14.9 0.1 7.5 6.5 0.0 2.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 OAG42006.1 - 0.13 11.5 0.3 0.47 9.7 0.1 1.9 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain AA_permease_2 PF13520.6 OAG42007.1 - 3.7e-49 167.7 48.9 4.9e-49 167.3 48.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAG42007.1 - 1.3e-16 60.3 43.8 1.8e-16 59.9 43.8 1.1 1 0 0 1 1 1 1 Amino acid permease DUF4307 PF14155.6 OAG42007.1 - 0.32 10.8 0.0 0.32 10.8 0.0 3.8 4 1 1 5 5 5 0 Domain of unknown function (DUF4307) DUF4131 PF13567.6 OAG42007.1 - 9.9 5.8 19.5 7.8 6.1 6.5 4.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) Sugar_tr PF00083.24 OAG42008.1 - 4.7e-92 309.2 24.8 5.9e-92 308.9 24.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG42008.1 - 6.1e-24 84.6 33.5 1e-23 83.9 29.3 2.2 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 OAG42008.1 - 4.5e-05 22.1 7.7 0.00011 20.7 1.7 2.2 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) PilJ PF13675.6 OAG42008.1 - 0.19 11.7 0.1 0.62 10.1 0.0 1.8 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Methyltransf_31 PF13847.6 OAG42009.1 - 5.5e-21 74.9 0.0 7e-21 74.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG42009.1 - 8.4e-21 74.5 0.3 2.6e-20 72.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAG42009.1 - 2.1e-17 63.2 0.1 3.5e-17 62.5 0.1 1.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 OAG42009.1 - 1.2e-16 61.1 0.0 3e-16 59.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG42009.1 - 9.9e-14 51.9 0.0 1.9e-13 51.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAG42009.1 - 3.4e-12 46.5 0.0 5.5e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 OAG42009.1 - 1.9e-09 37.6 0.2 5.9e-09 36.0 0.0 1.8 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 OAG42009.1 - 4.2e-06 26.4 0.2 1.2e-05 24.9 0.1 1.8 2 0 0 2 2 2 1 Methyltransferase small domain UPF0020 PF01170.18 OAG42009.1 - 0.00011 22.0 0.1 0.0027 17.4 0.1 2.5 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 PrmA PF06325.13 OAG42009.1 - 0.00014 21.3 0.3 0.00022 20.7 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.19 OAG42009.1 - 0.00039 20.6 0.0 0.00088 19.4 0.0 1.6 1 1 0 1 1 1 1 FtsJ-like methyltransferase CMAS PF02353.20 OAG42009.1 - 0.00055 19.3 1.0 0.0011 18.3 0.3 1.8 1 1 1 2 2 2 1 Mycolic acid cyclopropane synthetase CheR PF01739.18 OAG42009.1 - 0.059 12.9 0.0 1.7 8.1 0.0 2.2 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain Methyltransf_18 PF12847.7 OAG42009.1 - 0.065 13.2 0.1 0.13 12.2 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain NodS PF05401.11 OAG42009.1 - 0.11 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_32 PF13679.6 OAG42009.1 - 0.12 12.4 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Dicty_REP PF05086.12 OAG42010.1 - 2 6.3 4.3 2.6 5.9 4.3 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein CDV3 PF15359.6 OAG42010.1 - 5 7.6 7.9 0.94 10.0 1.1 2.5 2 0 0 2 2 2 0 Carnitine deficiency-associated protein 3 DUF3336 PF11815.8 OAG42011.1 - 5.9e-27 94.1 0.1 1.1e-24 86.7 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF3336) Patatin PF01734.22 OAG42011.1 - 1.1e-10 42.1 0.1 4.8e-10 40.0 0.0 2.0 2 0 0 2 2 2 1 Patatin-like phospholipase RNase_H_2 PF13482.6 OAG42011.1 - 0.16 12.0 0.3 4.1 7.4 0.0 2.3 2 0 0 2 2 2 0 RNase_H superfamily Methyltransf_31 PF13847.6 OAG42012.1 - 2e-29 102.4 0.0 2.8e-29 101.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG42012.1 - 1.7e-26 92.7 0.0 2.7e-26 92.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG42012.1 - 1.6e-25 89.6 0.0 2.7e-25 88.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAG42012.1 - 6.1e-18 65.0 0.0 8.3e-18 64.6 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 OAG42012.1 - 5.5e-17 62.1 0.0 7.7e-17 61.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG42012.1 - 3.5e-16 59.7 0.0 5.6e-16 59.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 OAG42012.1 - 1.4e-12 47.6 0.0 2e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_4 PF02390.17 OAG42012.1 - 3.4e-08 33.1 0.0 6.7e-08 32.2 0.0 1.6 1 1 0 1 1 1 1 Putative methyltransferase MTS PF05175.14 OAG42012.1 - 3.2e-07 30.1 0.0 4.3e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_9 PF08003.11 OAG42012.1 - 9.2e-07 28.1 0.0 1.5e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) PCMT PF01135.19 OAG42012.1 - 3.8e-06 26.8 0.0 5e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_29 PF03141.16 OAG42012.1 - 1.1e-05 24.2 0.0 1.5e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase DREV PF05219.12 OAG42012.1 - 1.4e-05 24.3 0.0 2e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_8 PF05148.15 OAG42012.1 - 5.7e-05 23.1 0.0 0.00042 20.2 0.0 2.0 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltr_RsmB-F PF01189.17 OAG42012.1 - 0.00016 21.4 0.0 0.00025 20.8 0.0 1.2 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F NodS PF05401.11 OAG42012.1 - 0.00029 20.5 0.0 0.00043 20.0 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_PK PF05891.12 OAG42012.1 - 0.00041 19.9 0.0 0.00069 19.2 0.0 1.3 1 1 0 1 1 1 1 AdoMet dependent proline di-methyltransferase PrmA PF06325.13 OAG42012.1 - 0.00053 19.5 0.0 0.0007 19.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) TehB PF03848.14 OAG42012.1 - 0.0014 18.1 0.0 0.002 17.6 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_2 PF00891.18 OAG42012.1 - 0.0014 18.0 0.0 0.0018 17.6 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase domain CheR PF01739.18 OAG42012.1 - 0.0034 16.9 0.0 0.019 14.4 0.1 2.2 2 1 1 3 3 3 1 CheR methyltransferase, SAM binding domain UPF0020 PF01170.18 OAG42012.1 - 0.0046 16.7 0.1 0.03 14.0 0.1 2.1 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 FtsJ PF01728.19 OAG42012.1 - 0.006 16.7 0.0 0.0085 16.2 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_18 PF12847.7 OAG42012.1 - 0.029 14.3 0.0 0.045 13.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.6 OAG42012.1 - 0.051 13.6 0.0 0.073 13.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.20 OAG42012.1 - 0.12 11.7 0.0 0.15 11.4 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Questin_oxidase PF14027.6 OAG42013.1 - 1e-90 304.8 0.6 1.3e-90 304.4 0.6 1.2 1 0 0 1 1 1 1 Questin oxidase-like Sec2p PF06428.11 OAG42014.1 - 1.4e-26 92.3 10.7 1.4e-26 92.3 10.7 2.5 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p DUF812 PF05667.11 OAG42014.1 - 0.0038 16.2 12.6 0.006 15.5 12.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Bac_DnaA PF00308.18 OAG42014.1 - 0.037 13.9 0.6 0.064 13.1 0.6 1.3 1 0 0 1 1 1 0 Bacterial dnaA protein DUF3584 PF12128.8 OAG42014.1 - 0.083 10.4 21.9 0.13 9.7 21.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF2786 PF10979.8 OAG42014.1 - 0.15 12.0 3.7 0.19 11.6 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2786) Fib_alpha PF08702.10 OAG42014.1 - 0.17 12.0 12.3 2.5 8.3 4.0 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF5339 PF17274.2 OAG42014.1 - 0.37 11.7 17.2 0.14 13.0 0.5 3.4 2 1 1 3 3 3 0 Family of unknown function (DUF5339) GCN5L1 PF06320.13 OAG42014.1 - 0.53 10.4 10.5 0.072 13.2 3.4 2.5 2 1 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) ADIP PF11559.8 OAG42014.1 - 0.98 9.5 21.9 3.2 7.8 11.1 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding AAA_13 PF13166.6 OAG42014.1 - 2.2 6.8 13.7 4.2 5.9 13.7 1.3 1 0 0 1 1 1 0 AAA domain SlyX PF04102.12 OAG42014.1 - 4.3 8.0 13.8 3.4 8.3 2.3 3.3 1 1 1 3 3 3 0 SlyX dsDNA_bind PF01984.20 OAG42015.1 - 7.8e-36 122.7 11.6 7.8e-36 122.7 11.6 1.3 2 0 0 2 2 2 1 Double-stranded DNA-binding domain Med4 PF10018.9 OAG42015.1 - 0.21 11.2 5.9 0.36 10.5 1.6 2.1 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 DUF4615 PF15393.6 OAG42015.1 - 0.42 11.2 3.3 0.22 12.1 1.1 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4615) Spexin PF15171.6 OAG42015.1 - 1.5 9.1 6.3 6.7 7.0 0.6 2.1 1 1 1 2 2 2 0 Neuropeptide secretory protein family, NPQ, spexin Coq4 PF05019.13 OAG42016.1 - 1.3e-65 220.8 0.0 1.6e-65 220.6 0.0 1.0 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 GyrI-like PF06445.15 OAG42016.1 - 0.02 15.2 0.1 0.58 10.4 0.0 2.1 2 0 0 2 2 2 0 GyrI-like small molecule binding domain SMP PF04927.12 OAG42017.1 - 3.9e-05 24.0 12.4 0.51 10.9 0.9 4.1 2 2 2 4 4 4 4 Seed maturation protein B12D PF06522.11 OAG42018.1 - 0.0035 17.1 0.0 0.0052 16.6 0.0 1.3 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit SET PF00856.28 OAG42020.1 - 7.7e-14 52.4 0.4 7.7e-14 52.4 0.4 3.8 2 2 0 2 2 2 1 SET domain AWS PF17907.1 OAG42020.1 - 1.6e-08 34.5 5.0 1.6e-08 34.5 5.0 2.3 3 0 0 3 3 3 1 AWS domain Peptidase_M20 PF01546.28 OAG42021.1 - 4.1e-23 82.2 0.1 6.5e-23 81.5 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 OAG42021.1 - 1e-12 47.9 0.0 1.9e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain 2-Hacid_dh_C PF02826.19 OAG42022.1 - 6.1e-41 139.7 0.0 1.1e-40 138.9 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 OAG42022.1 - 6.6e-07 29.1 0.0 1.5e-06 27.9 0.0 1.7 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 OAG42022.1 - 0.0066 16.6 0.0 0.25 11.5 0.0 2.3 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase ADH_N PF08240.12 OAG42023.1 - 5e-27 93.9 0.6 5e-27 93.9 0.6 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG42023.1 - 4.4e-14 52.6 0.0 6.8e-14 52.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 OAG42023.1 - 0.0001 21.9 0.7 0.013 15.0 0.4 2.6 2 1 0 2 2 2 2 Glucose dehydrogenase C-terminus Ank_2 PF12796.7 OAG42024.1 - 4.1e-97 318.9 2.6 1.7e-14 54.2 0.0 11.1 3 3 6 10 10 10 10 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OAG42024.1 - 1.9e-70 232.0 11.4 5.9e-09 36.0 0.0 15.1 8 3 8 16 16 16 12 Ankyrin repeats (many copies) Ank_4 PF13637.6 OAG42024.1 - 8.2e-67 220.8 12.7 1.7e-09 38.0 0.0 16.0 8 2 8 17 17 17 12 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG42024.1 - 3.5e-62 199.0 8.0 0.00077 19.7 0.0 20.1 20 0 0 20 20 19 11 Ankyrin repeat Ank PF00023.30 OAG42024.1 - 4.1e-55 181.9 8.5 0.00095 19.5 0.0 18.2 20 0 0 20 20 18 11 Ankyrin repeat PNP_UDP_1 PF01048.20 OAG42024.1 - 6.1e-10 38.7 0.0 1.2e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Phosphorylase superfamily NACHT PF05729.12 OAG42024.1 - 1.1e-05 25.4 0.1 5.4e-05 23.2 0.0 2.1 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 OAG42024.1 - 4.5e-05 23.9 0.2 0.00023 21.6 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 OAG42024.1 - 0.00018 21.8 0.1 0.001 19.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 OAG42024.1 - 0.0066 16.2 0.0 0.028 14.2 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_30 PF13604.6 OAG42024.1 - 0.02 14.6 0.0 0.051 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain PIF1 PF05970.14 OAG42024.1 - 0.039 13.1 0.0 0.067 12.3 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase DUF2075 PF09848.9 OAG42024.1 - 0.058 12.6 0.0 0.088 12.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) cobW PF02492.19 OAG42024.1 - 0.14 11.8 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 OAG42024.1 - 0.15 11.0 0.0 0.34 9.9 0.0 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ADH_N PF08240.12 OAG42025.1 - 1.2e-19 70.2 0.1 2.5e-19 69.2 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG42025.1 - 8e-18 64.7 1.5 2.3e-17 63.2 0.8 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase His_Phos_1 PF00300.22 OAG42025.1 - 0.049 13.3 0.0 0.086 12.5 0.0 1.4 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) BPL_LplA_LipB_2 PF16917.5 OAG42025.1 - 0.084 12.4 0.0 0.19 11.2 0.0 1.6 1 0 0 1 1 1 0 Biotin/lipoate A/B protein ligase family Transp_cyt_pur PF02133.15 OAG42026.1 - 1.6e-22 79.9 34.9 3.1e-22 79.0 34.9 1.4 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin adh_short PF00106.25 OAG42026.1 - 1.3e-10 41.1 0.0 2.4e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG42026.1 - 0.085 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Cupin_2 PF07883.11 OAG42027.1 - 1.6e-11 43.8 0.0 4.2e-05 23.2 0.0 2.3 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.19 OAG42027.1 - 6.8e-09 35.8 0.0 0.0012 18.8 0.0 2.4 2 0 0 2 2 2 2 AraC-like ligand binding domain Cupin_3 PF05899.12 OAG42027.1 - 2.7e-07 30.2 0.0 0.022 14.4 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF861) Cupin_6 PF12852.7 OAG42027.1 - 0.005 16.6 0.0 1.5 8.5 0.0 2.3 2 0 0 2 2 2 2 Cupin EutQ PF06249.12 OAG42027.1 - 0.099 12.4 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutQ Sec61_beta PF03911.16 OAG42028.1 - 4.2e-18 65.1 0.6 5.5e-18 64.7 0.6 1.2 1 0 0 1 1 1 1 Sec61beta family LRR_4 PF12799.7 OAG42029.1 - 5.7e-35 118.8 34.6 3.6e-09 36.7 2.3 6.6 3 1 4 8 8 8 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OAG42029.1 - 1.3e-27 95.3 36.4 7.2e-11 41.7 2.9 5.4 3 2 1 5 5 5 5 Leucine rich repeat LRR_9 PF14580.6 OAG42029.1 - 7e-15 55.0 29.4 1e-05 25.1 1.1 3.7 1 1 5 6 6 6 6 Leucine-rich repeat LRR_1 PF00560.33 OAG42029.1 - 2.8e-06 27.1 28.9 0.61 10.9 0.5 9.4 9 2 0 9 9 9 3 Leucine Rich Repeat LRR_6 PF13516.6 OAG42029.1 - 5.6e-05 22.9 27.7 0.41 10.8 0.5 8.5 9 0 0 9 9 9 4 Leucine Rich repeat UB2H PF14814.6 OAG42029.1 - 0.11 12.5 1.0 13 5.9 0.0 3.6 2 1 2 4 4 4 0 Bifunctional transglycosylase second domain Fibrillarin PF01269.17 OAG42030.1 - 2.3e-103 344.2 0.0 2.8e-103 343.9 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 OAG42030.1 - 7.4e-06 25.8 0.0 1.2e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltr_RsmB-F PF01189.17 OAG42030.1 - 0.025 14.2 0.0 0.081 12.6 0.0 1.7 2 0 0 2 2 2 0 16S rRNA methyltransferase RsmB/F PCMT PF01135.19 OAG42030.1 - 0.094 12.5 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FAD_binding_3 PF01494.19 OAG42032.1 - 2.3e-17 63.3 0.1 3.6e-17 62.6 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 OAG42032.1 - 2.2e-07 30.4 0.3 0.0001 21.7 0.2 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG42032.1 - 1.4e-06 28.4 0.8 3.4e-06 27.2 0.8 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAG42032.1 - 6e-06 26.1 6.4 0.017 14.7 4.8 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Amino_oxidase PF01593.24 OAG42032.1 - 1.3e-05 24.7 1.2 0.036 13.3 0.6 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 OAG42032.1 - 1.6e-05 24.5 0.3 2.7e-05 23.7 0.3 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 OAG42032.1 - 0.0001 21.3 2.6 0.073 11.9 3.0 3.0 3 0 0 3 3 3 1 Tryptophan halogenase Pyr_redox PF00070.27 OAG42032.1 - 0.00011 22.6 1.9 0.00048 20.6 0.4 2.6 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAG42032.1 - 0.00096 18.3 6.8 0.0023 17.1 6.8 1.6 1 0 0 1 1 1 1 FAD binding domain SE PF08491.10 OAG42032.1 - 0.0062 15.6 0.1 0.013 14.6 0.1 1.5 1 1 0 1 1 1 1 Squalene epoxidase Thi4 PF01946.17 OAG42032.1 - 0.019 14.2 0.6 0.032 13.5 0.6 1.4 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.22 OAG42032.1 - 0.046 12.8 3.8 0.087 11.9 3.8 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 OAG42032.1 - 0.087 12.1 2.8 0.72 9.0 3.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 OAG42032.1 - 0.092 12.0 2.0 0.22 10.8 2.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 OAG42032.1 - 0.095 11.4 6.1 0.08 11.6 4.6 1.6 2 0 0 2 2 2 0 HI0933-like protein Rossmann-like PF10727.9 OAG42032.1 - 0.11 12.4 0.2 0.25 11.2 0.2 1.6 1 0 0 1 1 1 0 Rossmann-like domain 3HCDH_N PF02737.18 OAG42032.1 - 0.4 10.6 2.0 1.1 9.1 1.2 2.1 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Cation_efflux PF01545.21 OAG42033.1 - 3.2e-16 59.6 7.5 4.1e-16 59.3 7.5 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 OAG42033.1 - 2.1e-11 43.8 1.5 5.6e-11 42.4 1.5 1.6 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter GPDPase_memb PF10110.9 OAG42033.1 - 0.096 11.5 0.1 0.096 11.5 0.1 1.9 3 0 0 3 3 3 0 Membrane domain of glycerophosphoryl diester phosphodiesterase Spt20 PF12090.8 OAG42035.1 - 1.5e-41 142.5 0.0 1.5e-41 142.5 0.0 7.7 3 2 2 5 5 5 1 Spt20 family Amidohydro_1 PF01979.20 OAG42036.1 - 7e-24 84.8 0.5 8.1e-23 81.3 0.5 2.0 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 OAG42036.1 - 8.5e-16 58.5 0.4 1.4e-07 31.4 0.0 2.5 2 1 0 2 2 2 2 Amidohydrolase family AA_permease PF00324.21 OAG42037.1 - 2e-103 346.5 37.8 2.3e-103 346.4 37.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAG42037.1 - 1.3e-26 93.5 41.7 1.6e-26 93.2 41.7 1.1 1 0 0 1 1 1 1 Amino acid permease Zn_clus PF00172.18 OAG42038.1 - 2.1e-08 34.1 7.4 3.3e-08 33.5 7.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BESS PF02944.20 OAG42038.1 - 0.052 13.4 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 BESS motif Opy2 PF09463.10 OAG42038.1 - 2 8.8 6.8 0.25 11.7 1.4 2.0 2 0 0 2 2 2 0 Opy2 protein GST_N_3 PF13417.6 OAG42039.1 - 3.9e-14 52.8 0.0 7e-14 52.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OAG42039.1 - 3e-13 49.8 0.0 5.3e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 OAG42039.1 - 4.8e-12 46.0 0.1 1.3e-11 44.7 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OAG42039.1 - 7.8e-09 35.7 0.0 1.9e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 OAG42039.1 - 8.5e-09 35.5 0.0 1.8e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OAG42039.1 - 7.3e-07 29.1 0.1 1.4e-06 28.2 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 OAG42039.1 - 0.017 15.7 0.0 0.52 10.9 0.0 2.3 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Amido_AtzD_TrzD PF09663.10 OAG42040.1 - 6.2e-116 387.4 4.3 7.2e-116 387.1 4.3 1.0 1 0 0 1 1 1 1 Amidohydrolase ring-opening protein (Amido_AtzD_TrzD) p450 PF00067.22 OAG42041.1 - 1.5e-76 258.1 0.0 2e-76 257.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.18 OAG42042.1 - 9.8e-40 136.3 0.4 1.8e-39 135.4 0.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 OAG42043.1 - 7.3e-42 143.5 27.6 7.3e-42 143.5 27.6 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG42043.1 - 4.8e-12 45.5 9.8 4.8e-12 45.5 9.8 3.0 2 1 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 OAG42043.1 - 2.4e-06 26.3 5.2 4.2e-06 25.5 5.2 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) NMT1 PF09084.11 OAG42044.1 - 1.8e-05 24.8 0.0 0.0083 16.1 0.0 2.4 2 0 0 2 2 2 2 NMT1/THI5 like Phosphonate-bd PF12974.7 OAG42044.1 - 0.048 13.2 0.0 0.064 12.8 0.0 1.2 1 0 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein Fungal_trans PF04082.18 OAG42045.1 - 1e-09 37.8 0.0 2.1e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pyr_redox_3 PF13738.6 OAG42046.1 - 1.2e-18 67.5 0.0 1.9e-16 60.2 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 OAG42046.1 - 2.5e-14 52.6 0.0 1.4e-13 50.1 0.0 1.9 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 OAG42046.1 - 1.7e-13 50.4 0.0 4.7e-11 42.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG42046.1 - 1.3e-10 41.3 0.1 2.5e-07 30.8 0.1 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 OAG42046.1 - 9.8e-10 38.1 0.0 3.2e-07 29.8 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 OAG42046.1 - 8.8e-05 22.5 1.0 0.88 9.6 0.9 3.8 3 1 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 OAG42046.1 - 0.00091 19.7 0.7 0.97 10.0 0.0 2.9 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAG42046.1 - 0.0016 18.1 9.2 0.35 10.4 0.8 4.1 3 2 0 4 4 4 2 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.19 OAG42046.1 - 0.0055 16.1 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Thi4 PF01946.17 OAG42046.1 - 0.0075 15.5 0.0 7.8 5.7 0.0 3.1 3 0 0 3 3 3 2 Thi4 family HI0933_like PF03486.14 OAG42046.1 - 0.0092 14.7 0.3 5.8 5.5 0.2 3.2 3 0 0 3 3 3 1 HI0933-like protein Shikimate_DH PF01488.20 OAG42046.1 - 0.066 13.3 0.0 0.83 9.7 0.0 2.5 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase AlaDh_PNT_C PF01262.21 OAG42046.1 - 0.086 12.1 0.0 6.3 6.0 0.0 2.5 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 OAG42046.1 - 0.094 13.2 0.1 1.7 9.2 0.0 2.9 4 0 0 4 4 4 0 Putative NAD(P)-binding NAD_binding_2 PF03446.15 OAG42046.1 - 0.1 12.7 0.0 0.6 10.3 0.0 2.2 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Lycopene_cycl PF05834.12 OAG42046.1 - 0.13 11.2 0.2 3.2 6.7 0.1 2.6 2 1 0 2 2 2 0 Lycopene cyclase protein Sugar_tr PF00083.24 OAG42047.1 - 7.3e-74 249.2 26.1 1.7e-62 211.8 7.6 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 OAG42047.1 - 2.5e-22 79.3 57.0 1.6e-13 50.3 8.8 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily adh_short_C2 PF13561.6 OAG42048.1 - 2.6e-62 210.5 0.5 3.3e-62 210.1 0.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG42048.1 - 1.6e-44 151.7 0.1 2.1e-44 151.3 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG42048.1 - 9.4e-10 38.7 0.1 1.4e-09 38.2 0.1 1.3 1 0 0 1 1 1 1 KR domain p450 PF00067.22 OAG42049.1 - 3.2e-62 210.8 0.0 4.1e-62 210.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 BATS PF06968.13 OAG42049.1 - 0.08 13.1 0.0 12 6.1 0.0 3.2 4 1 0 4 4 4 0 Biotin and Thiamin Synthesis associated domain Pro-rich PF15240.6 OAG42051.1 - 0.0024 18.2 33.9 0.006 16.9 33.9 1.6 1 0 0 1 1 1 1 Proline-rich Cyt-b5 PF00173.28 OAG42052.1 - 2.3e-13 50.1 0.0 3.2e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Ribosomal_S8 PF00410.19 OAG42053.1 - 1.5e-21 76.6 0.3 2.3e-21 76.1 0.3 1.3 1 1 0 1 1 1 1 Ribosomal protein S8 DUF202 PF02656.15 OAG42054.1 - 1.8e-13 50.7 0.1 1.8e-13 50.7 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) TMEM100 PF16311.5 OAG42054.1 - 0.012 15.2 0.4 0.017 14.7 0.4 1.3 1 0 0 1 1 1 0 Transmembrane protein 100 DUF2937 PF11157.8 OAG42054.1 - 0.13 12.0 0.1 0.13 12.0 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) UPF0182 PF03699.13 OAG42054.1 - 0.29 9.2 1.0 0.31 9.1 1.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) DUF4448 PF14610.6 OAG42054.1 - 6.3 6.5 5.6 38 4.0 5.6 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF4448) RRM_1 PF00076.22 OAG42056.1 - 7.2e-43 144.3 0.3 2.4e-20 72.1 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 OAG42056.1 - 2.4e-23 83.0 0.4 6.8e-23 81.6 0.2 2.0 2 0 0 2 2 2 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_occluded PF16842.5 OAG42056.1 - 8.8e-05 22.3 0.0 0.15 12.0 0.0 2.5 2 0 0 2 2 2 2 Occluded RNA-recognition motif RRM_3 PF08777.11 OAG42056.1 - 0.027 14.5 0.0 0.15 12.1 0.0 2.2 2 0 0 2 2 2 0 RNA binding motif PHM7_cyt PF14703.6 OAG42056.1 - 0.033 14.4 0.0 2.4 8.4 0.0 2.8 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter RRM_7 PF16367.5 OAG42056.1 - 0.073 13.2 0.0 2 8.6 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif Abhydrolase_3 PF07859.13 OAG42057.1 - 4.1e-27 95.4 0.0 5.6e-27 95.0 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 OAG42057.1 - 5.9e-17 61.6 0.0 7.5e-17 61.3 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase DUF2227 PF09988.9 OAG42057.1 - 0.11 12.4 0.3 0.45 10.4 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized metal-binding protein (DUF2227) Aminotran_4 PF01063.19 OAG42058.1 - 1.9e-40 139.1 0.0 2.3e-40 138.9 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV Fungal_trans_2 PF11951.8 OAG42059.1 - 2.8e-36 125.1 8.1 4.5e-36 124.5 8.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG42059.1 - 0.09 12.9 9.8 0.041 14.0 6.4 2.2 2 1 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain UNC-93 PF05978.16 OAG42060.1 - 8.8e-13 48.3 6.4 8.8e-13 48.3 6.4 2.4 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 OAG42060.1 - 2.8e-07 29.8 36.7 4.7e-06 25.8 36.7 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily CysA_C_terminal PF17850.1 OAG42061.1 - 0.8 10.3 0.0 0.8 10.3 0.0 2.9 3 0 0 3 3 3 0 CysA C-terminal regulatory domain TMF_TATA_bd PF12325.8 OAG42062.1 - 0.014 15.6 7.1 0.015 15.5 4.7 2.0 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Nnf1 PF03980.14 OAG42062.1 - 0.037 14.4 5.3 0.086 13.2 5.3 1.6 1 0 0 1 1 1 0 Nnf1 Spc7 PF08317.11 OAG42062.1 - 0.08 11.8 4.5 0.16 10.8 4.5 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4107 PF13389.6 OAG42062.1 - 0.11 12.7 0.4 0.21 11.7 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4107) Phage_HK97_TLTM PF06120.11 OAG42062.1 - 0.26 10.4 3.9 0.42 9.7 3.9 1.2 1 0 0 1 1 1 0 Tail length tape measure protein Fib_alpha PF08702.10 OAG42062.1 - 0.87 9.8 8.3 0.21 11.7 4.4 1.8 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family ADIP PF11559.8 OAG42062.1 - 1 9.5 11.1 3.5 7.7 11.2 1.8 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF641 PF04859.12 OAG42062.1 - 1.4 9.3 5.2 1.6 9.0 2.8 2.2 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) Atg14 PF10186.9 OAG42062.1 - 2 7.4 5.5 3.5 6.6 5.5 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF668 PF05003.12 OAG42062.1 - 2.5 8.6 4.1 2.5 8.6 0.0 2.8 3 1 0 3 3 3 0 Protein of unknown function (DUF668) BRE1 PF08647.11 OAG42062.1 - 5.6 7.1 11.1 3.4 7.8 7.8 2.3 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase Cu_bind_like PF02298.17 OAG42063.1 - 0.011 15.7 0.1 0.023 14.7 0.1 1.5 1 1 0 1 1 1 0 Plastocyanin-like domain SAP130_C PF16014.5 OAG42063.1 - 7.1 5.6 9.2 8.8 5.3 9.2 1.2 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus MFS_1 PF07690.16 OAG42064.1 - 7.8e-36 123.7 52.7 1.8e-31 109.3 34.3 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily FeoB_C PF07664.12 OAG42064.1 - 0.033 13.9 0.3 1.6 8.5 0.1 2.9 2 0 0 2 2 2 0 Ferrous iron transport protein B C terminus Phage_holin_2_4 PF16082.5 OAG42064.1 - 4.6 7.1 5.9 5.4 6.8 0.2 3.1 3 0 0 3 3 3 0 Bacteriophage holin family, superfamily II-like Ribosomal_L22 PF00237.19 OAG42065.1 - 8.6e-42 141.6 0.1 8.6e-42 141.6 0.1 1.4 2 0 0 2 2 2 1 Ribosomal protein L22p/L17e Clr2 PF10383.9 OAG42066.1 - 2.9e-22 80.0 0.1 1.2e-21 78.0 0.0 2.1 2 0 0 2 2 2 1 Transcription-silencing protein Clr2 Clr2_transil PF16761.5 OAG42066.1 - 6.8e-13 49.2 0.3 1.8e-12 47.9 0.3 1.8 1 0 0 1 1 1 1 Transcription-silencing protein, cryptic loci regulator Clr2 Bac_rhamnosid6H PF17389.2 OAG42068.1 - 1.8e-107 359.6 0.2 2.4e-107 359.1 0.2 1.2 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_N PF08531.10 OAG42068.1 - 1.5e-37 129.0 0.0 2.7e-37 128.2 0.0 1.4 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain Helicase_C PF00271.31 OAG42068.1 - 1.3e-25 89.9 0.0 3.3e-25 88.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 OAG42068.1 - 8.5e-25 87.5 0.0 1.8e-24 86.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Bac_rhamnosid PF05592.11 OAG42068.1 - 5.2e-24 84.2 0.0 1e-23 83.2 0.0 1.5 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase concanavalin-like domain Bac_rhamnosid_C PF17390.2 OAG42068.1 - 1.3e-20 72.9 0.0 3.9e-20 71.4 0.0 1.8 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain ResIII PF04851.15 OAG42068.1 - 2.6e-05 24.3 0.0 6.1e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit RelB_transactiv PF16181.5 OAG42070.1 - 0.023 15.0 1.6 3.3 7.9 0.1 3.4 3 0 0 3 3 3 0 RelB transactivation domain PRIMA1 PF16101.5 OAG42070.1 - 0.81 9.7 5.6 2.4 8.2 5.6 1.8 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 ATP-synt_G PF04718.15 OAG42071.1 - 6e-32 110.4 0.2 1.8e-31 109.0 0.0 1.7 2 0 0 2 2 2 1 Mitochondrial ATP synthase g subunit DUF4446 PF14584.6 OAG42071.1 - 0.062 13.3 0.0 0.09 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) FAM199X PF15814.5 OAG42071.1 - 5 6.1 8.2 8.7 5.3 8.2 1.3 1 0 0 1 1 1 0 Protein family FAM199X Telomere_reg-2 PF10193.9 OAG42072.1 - 0.015 15.7 0.0 0.048 14.1 0.0 1.8 1 0 0 1 1 1 0 Telomere length regulation protein Peptidase_S8 PF00082.22 OAG42073.1 - 1.9e-12 47.1 0.4 2.1e-12 47.0 0.4 1.1 1 0 0 1 1 1 1 Subtilase family Ank_2 PF12796.7 OAG42075.1 - 3e-58 194.4 3.9 1.4e-18 67.3 0.5 5.3 2 1 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAG42075.1 - 7.2e-51 169.9 16.7 1.1e-13 51.4 0.3 9.2 4 3 6 10 10 10 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG42075.1 - 9.9e-46 148.4 12.5 4.7e-06 26.5 0.1 11.2 11 0 0 11 11 11 9 Ankyrin repeat Ank PF00023.30 OAG42075.1 - 6.5e-43 143.4 15.2 1.7e-07 31.4 0.0 10.5 10 0 0 10 10 10 9 Ankyrin repeat Ank_5 PF13857.6 OAG42075.1 - 7.7e-38 128.1 13.0 1.9e-10 40.8 0.0 8.4 3 2 6 9 9 9 7 Ankyrin repeats (many copies) TAP42 PF04177.12 OAG42075.1 - 0.11 11.6 0.1 0.19 10.8 0.1 1.2 1 0 0 1 1 1 0 TAP42-like family Ank_2 PF12796.7 OAG42076.1 - 8.5e-22 77.5 0.0 1.6e-11 44.7 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 OAG42076.1 - 1.5e-17 63.2 0.4 0.0001 22.6 0.3 5.0 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 OAG42076.1 - 2.8e-16 59.4 0.7 1.5e-07 31.5 0.0 4.6 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG42076.1 - 4.8e-16 57.2 0.4 0.00018 21.6 0.0 5.5 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 OAG42076.1 - 4.8e-15 55.7 1.1 6.7e-09 36.1 0.0 3.9 2 1 0 3 3 3 3 Ankyrin repeats (many copies) NACHT PF05729.12 OAG42076.1 - 6.6e-10 39.2 0.1 1.6e-09 37.9 0.1 1.7 1 0 0 1 1 1 1 NACHT domain PNP_UDP_1 PF01048.20 OAG42076.1 - 6.6e-09 35.4 0.0 1.3e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Phosphorylase superfamily KAP_NTPase PF07693.14 OAG42076.1 - 0.0053 16.0 0.0 0.0094 15.2 0.0 1.3 1 0 0 1 1 1 1 KAP family P-loop domain Mg_chelatase PF01078.21 OAG42076.1 - 0.1 11.9 0.0 0.34 10.3 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 OAG42076.1 - 0.11 12.5 0.0 12 5.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) HlyIII PF03006.20 OAG42077.1 - 1.7e-46 158.8 17.7 2e-46 158.5 17.7 1.1 1 0 0 1 1 1 1 Haemolysin-III related SSF PF00474.17 OAG42078.1 - 9.9e-20 70.8 27.3 1.4e-19 70.3 27.3 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family DUF962 PF06127.11 OAG42078.1 - 0.083 13.0 0.6 9.2 6.4 0.6 3.7 1 1 0 1 1 1 0 Protein of unknown function (DUF962) YTH PF04146.15 OAG42081.1 - 6.9e-44 149.7 0.1 1.5e-43 148.6 0.1 1.6 1 1 0 1 1 1 1 YT521-B-like domain RRM_1 PF00076.22 OAG42081.1 - 1.9e-07 30.8 0.0 3.2e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Helo_like_N PF17111.5 OAG42082.1 - 7.7e-11 41.7 0.8 1.2e-10 41.1 0.8 1.3 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins HSP70 PF00012.20 OAG42082.1 - 0.00015 20.1 0.0 0.00031 19.1 0.0 1.4 1 0 0 1 1 1 1 Hsp70 protein SesA PF17107.5 OAG42082.1 - 0.0097 16.1 0.0 0.018 15.2 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases FUSC PF04632.12 OAG42082.1 - 0.16 10.4 2.4 1.9 6.9 0.4 2.3 2 0 0 2 2 2 0 Fusaric acid resistance protein family VWA_2 PF13519.6 OAG42083.1 - 2.7e-05 24.8 0.3 0.00021 21.9 0.0 2.6 3 0 0 3 3 3 1 von Willebrand factor type A domain VWA PF00092.28 OAG42083.1 - 0.0023 18.2 0.0 0.0095 16.2 0.0 2.1 1 1 0 1 1 1 1 von Willebrand factor type A domain Sugar_tr PF00083.24 OAG42084.1 - 9.5e-125 417.0 21.8 1.2e-124 416.7 21.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG42084.1 - 2e-18 66.5 37.5 1.7e-13 50.3 14.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.18 OAG42085.1 - 2e-15 56.6 1.0 1.6e-14 53.6 1.0 2.2 1 1 0 1 1 1 1 Fungal specific transcription factor domain WD40 PF00400.32 OAG42086.1 - 7.6e-10 39.2 15.3 2.4e-05 25.0 0.7 8.5 10 0 0 10 10 10 2 WD domain, G-beta repeat Nucleoporin_N PF08801.11 OAG42086.1 - 0.089 11.5 3.1 0.84 8.3 0.1 3.4 4 0 0 4 4 4 0 Nup133 N terminal like Oxidored_FMN PF00724.20 OAG42087.1 - 2.9e-41 141.9 0.0 4e-41 141.4 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family FMN_dh PF01070.18 OAG42087.1 - 0.021 13.8 0.0 0.054 12.5 0.0 1.6 2 0 0 2 2 2 0 FMN-dependent dehydrogenase Ribosomal_S17_N PF16205.5 OAG42088.1 - 2.1e-33 114.5 0.2 4e-33 113.6 0.2 1.5 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 OAG42088.1 - 5e-22 77.8 0.1 1.4e-21 76.4 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein S17 Spc7_N PF15402.6 OAG42089.1 - 2e-256 853.8 71.9 2e-256 853.8 71.9 2.8 3 0 0 3 3 3 1 N-terminus of kinetochore NMS complex subunit Spc7 Spc7 PF08317.11 OAG42089.1 - 5.6e-101 337.5 8.0 5.6e-101 337.5 8.0 1.7 2 0 0 2 2 2 1 Spc7 kinetochore protein Spc7_C2 PF15577.6 OAG42089.1 - 6.9e-09 35.7 0.1 1.4e-08 34.6 0.1 1.6 1 0 0 1 1 1 1 Spc7_C2 DUF5069 PF16798.5 OAG42089.1 - 0.55 10.4 3.4 9.9 6.4 0.3 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5069) DEAD PF00270.29 OAG42090.1 - 5.8e-47 159.7 0.0 1.7e-46 158.2 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAG42090.1 - 2.1e-29 102.1 0.1 1.1e-28 99.8 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG42090.1 - 0.02 14.9 0.0 0.048 13.7 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit PRAI PF00697.22 OAG42090.1 - 0.11 12.3 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase DUF2986 PF11661.8 OAG42090.1 - 1.9 9.1 6.7 0.28 11.8 1.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2986) Pkinase PF00069.25 OAG42091.1 - 9.1e-66 221.9 0.1 2.3e-65 220.6 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG42091.1 - 8.9e-43 146.4 0.0 1.3e-42 145.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAG42091.1 - 3.5e-09 36.4 0.0 4.4e-08 32.8 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 OAG42091.1 - 6.6e-06 25.3 0.0 6.6e-06 25.3 0.0 2.4 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 OAG42091.1 - 0.022 14.7 3.6 0.56 10.1 0.3 3.0 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.14 OAG42091.1 - 0.036 13.4 0.2 0.16 11.3 0.0 2.0 2 1 1 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family Prenyltrans PF00432.21 OAG42093.1 - 3.7e-26 90.6 10.5 2.4e-05 24.0 0.0 6.1 6 1 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 OAG42093.1 - 0.045 12.8 0.0 0.32 10.0 0.0 2.2 1 1 2 3 3 3 0 Squalene-hopene cyclase C-terminal domain Pes-10 PF07149.11 OAG42093.1 - 2 7.4 5.9 3 6.8 5.9 1.1 1 0 0 1 1 1 0 Pes-10 eIF3_subunit PF08597.10 OAG42094.1 - 1.2e-67 228.4 33.2 1.3e-67 228.2 33.2 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit Peptidase_M56 PF05569.11 OAG42094.1 - 0.23 10.6 0.0 0.42 9.8 0.0 1.4 1 0 0 1 1 1 0 BlaR1 peptidase M56 Enolase_C PF00113.22 OAG42095.1 - 1.4e-154 513.7 0.0 1.8e-154 513.3 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 OAG42095.1 - 3.2e-58 195.5 0.2 6.2e-58 194.6 0.1 1.5 2 0 0 2 2 2 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 OAG42095.1 - 3.2e-07 30.2 0.0 5.3e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 OAG42095.1 - 0.0034 16.6 0.8 0.16 11.1 0.1 2.8 3 0 0 3 3 3 1 Methylaspartate ammonia-lyase C-terminus AAA PF00004.29 OAG42096.1 - 6.2e-43 146.4 0.0 1.2e-42 145.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 OAG42096.1 - 2.5e-12 46.6 0.1 8.4e-11 41.7 0.0 2.4 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 OAG42096.1 - 2e-10 40.3 0.2 4.9e-10 39.0 0.0 1.8 2 0 0 2 2 1 1 AAA+ lid domain AAA_16 PF13191.6 OAG42096.1 - 2.7e-07 31.1 0.0 0.00011 22.6 0.1 2.7 2 1 1 3 3 2 1 AAA ATPase domain AAA_5 PF07728.14 OAG42096.1 - 1.7e-06 28.0 0.0 4.3e-05 23.5 0.0 2.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 OAG42096.1 - 2.4e-06 27.8 0.0 8e-06 26.1 0.0 1.9 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 OAG42096.1 - 7.7e-06 25.7 0.0 1.6e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 OAG42096.1 - 6.1e-05 23.6 0.1 0.0042 17.6 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 OAG42096.1 - 0.00017 21.9 0.0 0.0031 17.8 0.0 2.5 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 OAG42096.1 - 0.00037 19.7 0.0 0.001 18.3 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_7 PF12775.7 OAG42096.1 - 0.00073 19.1 0.0 0.0015 18.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region TIP49 PF06068.13 OAG42096.1 - 0.002 17.4 0.0 0.0038 16.5 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 OAG42096.1 - 0.0034 17.5 0.0 0.0095 16.1 0.0 1.8 2 0 0 2 2 1 1 AAA domain Mg_chelatase PF01078.21 OAG42096.1 - 0.004 16.6 0.0 0.0083 15.5 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Prot_ATP_OB_N PF17758.1 OAG42096.1 - 0.0047 16.5 0.0 0.014 15.0 0.0 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB N-terminal domain TsaE PF02367.17 OAG42096.1 - 0.0055 16.7 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 OAG42096.1 - 0.0064 16.2 0.0 0.016 15.0 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.6 OAG42096.1 - 0.0085 16.1 0.0 0.019 15.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.11 OAG42096.1 - 0.0092 15.8 0.0 0.022 14.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 OAG42096.1 - 0.0093 15.7 0.0 0.029 14.1 0.0 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain RNA_helicase PF00910.22 OAG42096.1 - 0.011 16.1 0.0 0.023 15.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase DUF4482 PF14818.6 OAG42096.1 - 0.019 15.8 1.0 0.019 15.8 1.0 1.8 2 0 0 2 2 1 0 Domain of unknown function (DUF4482) AAA_11 PF13086.6 OAG42096.1 - 0.021 14.6 0.6 0.34 10.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain Thymidylate_kin PF02223.17 OAG42096.1 - 0.025 14.2 0.1 6 6.5 0.0 2.6 3 0 0 3 3 2 0 Thymidylate kinase ATPase PF06745.13 OAG42096.1 - 0.028 13.8 0.4 0.12 11.7 0.0 2.2 3 0 0 3 3 3 0 KaiC AAA_24 PF13479.6 OAG42096.1 - 0.03 14.1 0.0 0.087 12.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 OAG42096.1 - 0.073 13.0 0.1 0.19 11.7 0.0 1.7 2 0 0 2 2 2 0 NACHT domain PhoH PF02562.16 OAG42096.1 - 0.077 12.4 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein ATPase_2 PF01637.18 OAG42096.1 - 0.091 12.7 0.4 0.36 10.7 0.0 2.3 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea Zeta_toxin PF06414.12 OAG42096.1 - 0.098 11.9 0.0 0.26 10.5 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin Parvo_NS1 PF01057.17 OAG42096.1 - 0.1 11.6 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_28 PF13521.6 OAG42096.1 - 0.11 12.8 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 OAG42096.1 - 0.11 12.1 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 OAG42096.1 - 0.11 12.2 0.0 0.28 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain OmpH PF03938.14 OAG42096.1 - 1.7 9.0 8.5 0.73 10.2 3.9 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) MFS_1 PF07690.16 OAG42098.1 - 2.7e-23 82.5 66.7 1.7e-19 70.0 49.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Cytochrom_C550 PF14495.6 OAG42099.1 - 0.0046 16.7 0.4 0.009 15.7 0.4 1.4 1 0 0 1 1 1 1 Cytochrome c-550 domain Mitoc_mL59 PF18126.1 OAG42100.1 - 6.6e-51 172.0 2.3 1.1e-50 171.2 2.3 1.4 1 1 0 1 1 1 1 Mitochondrial ribosomal protein mL59 VRR_NUC PF08774.11 OAG42100.1 - 0.17 12.0 0.0 0.29 11.2 0.0 1.4 1 0 0 1 1 1 0 VRR-NUC domain SIS PF01380.22 OAG42101.1 - 8.7e-58 193.8 0.0 7.5e-31 106.7 0.1 2.4 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 OAG42101.1 - 9.8e-18 64.6 0.0 2.1e-17 63.6 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 OAG42101.1 - 1e-10 41.6 0.0 2.2e-10 40.5 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain Suf PF05843.14 OAG42101.1 - 1.7e-05 25.0 4.6 0.004 17.2 0.1 3.3 3 0 0 3 3 3 1 Suppressor of forked protein (Suf) TPR_14 PF13428.6 OAG42101.1 - 0.00023 21.7 2.8 0.12 13.3 0.0 5.1 5 1 1 6 6 6 1 Tetratricopeptide repeat GATase_4 PF13230.6 OAG42101.1 - 0.00075 18.5 0.0 0.0012 17.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II TPR_19 PF14559.6 OAG42101.1 - 0.17 12.4 0.3 9.5 6.8 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Glyco_transf_22 PF03901.17 OAG42102.1 - 1.1e-76 258.8 18.1 1.3e-76 258.5 18.1 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family BCHF PF07284.11 OAG42102.1 - 0.81 9.7 4.2 1 9.4 0.5 2.5 3 0 0 3 3 3 0 2-vinyl bacteriochlorophyllide hydratase (BCHF) Ank_2 PF12796.7 OAG42103.1 - 2.1e-101 332.6 13.5 1.8e-16 60.4 0.4 10.4 3 3 6 10 10 10 10 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAG42103.1 - 6.6e-69 227.5 7.0 4.6e-11 43.0 0.0 13.1 5 3 12 17 17 17 13 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG42103.1 - 1.4e-66 212.5 2.6 0.00029 21.0 0.0 18.3 18 0 0 18 18 18 12 Ankyrin repeat Ank PF00023.30 OAG42103.1 - 3.4e-65 213.8 15.3 3.2e-05 24.2 0.0 17.4 16 1 1 17 17 17 13 Ankyrin repeat Ank_5 PF13857.6 OAG42103.1 - 7.2e-64 211.0 16.1 4.3e-11 42.8 0.0 13.8 5 4 9 14 14 14 10 Ankyrin repeats (many copies) CorA PF01544.18 OAG42103.1 - 0.024 14.0 6.9 0.038 13.3 1.1 2.7 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein T3SchapCesA PF11439.8 OAG42103.1 - 5.6 7.2 5.8 3.4 7.9 1.2 2.8 3 0 0 3 3 3 0 Type III secretion system filament chaperone CesA DUF2370 PF10176.9 OAG42103.1 - 6.1 6.4 8.6 34 4.0 3.6 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2370) ArfGap PF01412.18 OAG42104.1 - 1e-39 135.2 0.4 2.6e-39 133.9 0.4 1.7 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf SopE_GEF PF07487.13 OAG42104.1 - 0.052 13.6 0.3 0.052 13.6 0.3 1.9 2 0 0 2 2 2 0 SopE GEF domain CUE PF02845.16 OAG42104.1 - 0.14 11.9 0.1 0.32 10.8 0.1 1.6 1 0 0 1 1 1 0 CUE domain YscJ_FliF PF01514.17 OAG42104.1 - 0.31 10.7 0.1 0.31 10.7 0.1 1.9 2 0 0 2 2 2 0 Secretory protein of YscJ/FliF family Zn-ribbon_8 PF09723.10 OAG42105.1 - 0.12 12.5 1.8 0.26 11.4 1.8 1.5 1 0 0 1 1 1 0 Zinc ribbon domain Rubredoxin_2 PF18073.1 OAG42105.1 - 0.68 9.7 7.2 1 9.1 1.1 2.4 2 0 0 2 2 2 0 Rubredoxin metal binding domain zf-Mss51 PF13824.6 OAG42105.1 - 2.8 8.1 6.9 3.7 7.7 1.7 3.1 2 1 1 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 Proteasome PF00227.26 OAG42106.1 - 1.6e-45 154.9 0.0 2.2e-31 108.8 0.0 2.3 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.9 OAG42106.1 - 5.7e-12 45.1 1.0 6.3e-12 44.9 0.0 1.6 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DUF5633 PF18656.1 OAG42106.1 - 1.4 8.9 6.1 0.31 11.0 1.2 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5633) DMRL_synthase PF00885.19 OAG42107.1 - 6.5e-55 184.8 0.0 8.6e-55 184.4 0.0 1.2 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase Fungal_trans_2 PF11951.8 OAG42109.1 - 7.4e-27 94.1 9.9 9.6e-27 93.8 9.9 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG42109.1 - 2.5e-08 33.9 7.4 7.1e-08 32.4 7.4 1.9 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_N PF08240.12 OAG42110.1 - 9.4e-24 83.4 1.4 1.6e-23 82.6 1.4 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG42110.1 - 1.7e-20 73.3 0.6 2.3e-20 72.9 0.0 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 OAG42110.1 - 6e-07 29.0 0.1 1.2e-06 28.0 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.6 OAG42110.1 - 0.00017 22.6 0.0 0.00031 21.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 OAG42110.1 - 0.00057 19.3 0.1 0.00094 18.6 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.21 OAG42110.1 - 0.042 13.6 0.1 0.063 13.0 0.1 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase DUF4451 PF14616.6 OAG42110.1 - 0.071 13.3 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4451) 3HCDH_N PF02737.18 OAG42110.1 - 0.071 13.0 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PhyH PF05721.13 OAG42111.1 - 5.7e-23 82.3 0.0 7.7e-23 81.8 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 OAG42111.1 - 0.14 10.9 0.0 0.17 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1479) DUF3445 PF11927.8 OAG42112.1 - 3.2e-38 131.6 0.0 7.9e-38 130.3 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3445) CedA PF10729.9 OAG42112.1 - 0.074 12.9 0.1 0.42 10.5 0.0 2.2 2 0 0 2 2 2 0 Cell division activator CedA AA_permease_2 PF13520.6 OAG42113.1 - 2.2e-49 168.5 47.5 2.9e-49 168.1 47.5 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAG42113.1 - 1e-24 87.0 43.1 1.4e-24 86.6 43.1 1.0 1 0 0 1 1 1 1 Amino acid permease PsbW PF07123.12 OAG42113.1 - 0.22 11.5 2.7 2.5 8.1 0.1 3.0 3 0 0 3 3 3 0 Photosystem II reaction centre W protein (PsbW) DUF1418 PF07214.12 OAG42113.1 - 7 6.6 10.1 10 6.1 0.1 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF1418) Aminotran_3 PF00202.21 OAG42114.1 - 6e-118 394.0 0.0 7e-118 393.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 OAG42114.1 - 0.006 15.8 0.0 0.011 14.9 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II OAM_dimer PF16554.5 OAG42114.1 - 0.053 14.0 0.0 0.12 12.9 0.0 1.5 1 0 0 1 1 1 0 Dimerisation domain of d-ornithine 4,5-aminomutase MRI PF15325.6 OAG42115.1 - 0.00043 21.3 0.1 0.011 16.9 0.0 2.4 1 1 1 2 2 2 1 Modulator of retrovirus infection Spo12 PF05032.12 OAG42116.1 - 4.7 7.2 9.1 0.18 11.7 1.1 2.2 2 0 0 2 2 2 0 Spo12 family HLH PF00010.26 OAG42117.1 - 2.2e-11 43.5 0.5 3.6e-11 42.8 0.5 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PHO4 PF01384.20 OAG42118.1 - 7.2e-118 393.5 13.8 8.3e-118 393.3 13.8 1.0 1 0 0 1 1 1 1 Phosphate transporter family Amidase PF01425.21 OAG42120.1 - 2.4e-104 349.8 0.0 3.2e-104 349.4 0.0 1.2 1 0 0 1 1 1 1 Amidase SieB PF14163.6 OAG42121.1 - 0.07 12.6 0.0 0.093 12.2 0.0 1.1 1 0 0 1 1 1 0 Super-infection exclusion protein B Syja_N PF02383.18 OAG42122.1 - 2.2e-74 250.7 0.0 5e-74 249.5 0.0 1.6 1 0 0 1 1 1 1 SacI homology domain TPR_14 PF13428.6 OAG42123.1 - 1.4e-05 25.5 1.4 0.16 12.8 0.0 5.3 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.17 OAG42123.1 - 2.3e-05 24.1 0.0 0.038 14.1 0.0 4.3 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 OAG42123.1 - 0.00054 20.1 0.0 0.044 13.9 0.0 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 OAG42123.1 - 0.0072 16.9 0.0 0.071 13.8 0.0 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 OAG42123.1 - 0.012 16.1 0.0 0.74 10.4 0.0 3.6 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 OAG42123.1 - 0.015 15.1 0.0 2 8.4 0.0 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 OAG42123.1 - 0.042 13.5 0.0 8.8 6.1 0.0 2.9 2 1 1 3 3 3 0 TPR repeat HrpJ PF07201.11 OAG42123.1 - 0.067 13.5 4.0 0.094 13.0 0.1 2.7 2 1 1 3 3 3 0 HrpJ-like domain TPR_17 PF13431.6 OAG42123.1 - 0.1 13.1 0.0 1.9 9.0 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_20 PF14561.6 OAG42123.1 - 0.1 12.9 0.0 0.47 10.8 0.0 2.2 2 1 1 3 3 3 0 Tetratricopeptide repeat IF-2B PF01008.17 OAG42123.1 - 0.15 11.3 0.0 0.46 9.7 0.0 1.6 1 1 0 2 2 2 0 Initiation factor 2 subunit family TPR_12 PF13424.6 OAG42123.1 - 0.16 12.3 0.9 3.8 7.9 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Adaptin_N PF01602.20 OAG42124.1 - 2.5e-87 293.6 0.2 3.2e-87 293.3 0.2 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 OAG42124.1 - 1e-07 32.2 0.1 0.00058 19.9 0.0 2.7 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 OAG42124.1 - 0.001 19.1 0.1 10 6.7 0.0 5.0 6 0 0 6 6 6 1 HEAT repeat HEAT_EZ PF13513.6 OAG42124.1 - 0.0013 19.2 3.5 0.57 10.7 0.0 4.6 4 1 1 5 5 5 1 HEAT-like repeat UPF0147 PF03685.13 OAG42124.1 - 0.071 13.2 0.1 4 7.6 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0147) HEAT_2 PF13646.6 OAG42124.1 - 0.087 13.2 5.4 0.3 11.5 0.1 3.8 4 0 0 4 4 4 0 HEAT repeats AP3D1 PF06375.11 OAG42124.1 - 6.5 7.0 11.4 1.7 8.9 0.0 2.8 2 1 1 3 3 3 0 AP-3 complex subunit delta-1 IF4E PF01652.18 OAG42126.1 - 1.6e-56 190.5 0.5 1.9e-56 190.3 0.5 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Mpv17_PMP22 PF04117.12 OAG42127.1 - 2.1e-16 59.9 0.0 4.1e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family Ribosomal_S5 PF00333.20 OAG42128.1 - 8.4e-27 92.9 1.7 1.1e-26 92.5 0.7 1.8 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 OAG42128.1 - 5.2e-23 80.3 0.0 8.7e-23 79.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain IKBKB_SDD PF18397.1 OAG42129.1 - 0.0071 15.7 0.2 0.0077 15.6 0.2 1.0 1 0 0 1 1 1 1 IQBAL scaffold dimerization domain OmpH PF03938.14 OAG42129.1 - 0.023 15.0 7.5 0.028 14.7 7.5 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF2057 PF09829.9 OAG42129.1 - 0.17 12.1 3.0 0.22 11.7 3.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) YtxH PF12732.7 OAG42129.1 - 0.29 11.7 4.9 11 6.7 4.8 2.2 1 1 0 1 1 1 0 YtxH-like protein Apolipoprotein PF01442.18 OAG42130.1 - 5.6e-07 29.6 9.6 0.0034 17.3 2.7 2.9 1 1 2 3 3 2 2 Apolipoprotein A1/A4/E domain FAM184 PF15665.5 OAG42130.1 - 0.0013 18.6 16.8 0.062 13.1 0.0 3.6 2 1 1 3 3 3 2 Family with sequence similarity 184, A and B XH PF03469.14 OAG42130.1 - 0.0016 18.4 6.1 3.1 7.7 0.2 3.7 3 1 0 3 3 3 3 XH domain ApoLp-III PF07464.11 OAG42130.1 - 0.0025 17.9 0.5 0.0025 17.9 0.5 4.3 2 1 2 4 4 3 1 Apolipophorin-III precursor (apoLp-III) YtxH PF12732.7 OAG42130.1 - 0.0085 16.6 20.8 9.9 6.8 0.5 5.9 3 2 0 3 3 3 1 YtxH-like protein Senescence PF06911.12 OAG42130.1 - 0.017 15.5 2.8 4.5 7.5 0.0 4.1 3 3 0 3 3 3 0 Senescence-associated protein TetR_C_25 PF17933.1 OAG42130.1 - 0.1 13.0 0.1 0.67 10.3 0.0 2.4 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Prominin PF05478.11 OAG42130.1 - 0.26 9.2 5.8 0.29 9.0 0.4 2.7 1 1 0 2 2 2 0 Prominin CarD_CdnL_TRCF PF02559.16 OAG42130.1 - 0.97 10.2 13.3 8.8 7.1 0.3 4.8 3 1 2 5 5 5 0 CarD-like/TRCF domain DUF643 PF04867.12 OAG42130.1 - 1.9 9.1 10.8 8.6 7.0 0.3 4.0 3 1 1 4 4 4 0 Protein of unknown function (DUF643) Laminin_II PF06009.12 OAG42130.1 - 4.1 7.4 10.9 2.8 8.0 0.2 3.5 2 1 2 4 4 4 0 Laminin Domain II GST_N_2 PF13409.6 OAG42131.1 - 8.1e-18 64.5 0.0 2e-17 63.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAG42131.1 - 6.2e-11 42.2 0.0 1.6e-10 40.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OAG42131.1 - 0.00056 20.1 0.0 0.0013 18.9 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OAG42131.1 - 0.00068 19.8 0.0 0.0014 18.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain LIM PF00412.22 OAG42132.1 - 1.3e-17 63.7 15.7 3.8e-09 36.6 5.1 2.3 2 0 0 2 2 2 2 LIM domain NAD_binding_5 PF07994.12 OAG42133.1 - 3.5e-144 480.1 0.2 4.2e-144 479.9 0.2 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 OAG42133.1 - 2.3e-45 153.3 2.3 3e-45 153.0 1.0 1.9 2 0 0 2 2 2 1 Myo-inositol-1-phosphate synthase SLAC1 PF03595.17 OAG42135.1 - 6.4e-80 268.8 51.7 7.4e-80 268.6 51.7 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel PIN_4 PF13638.6 OAG42136.1 - 0.0034 17.7 0.0 0.035 14.4 0.0 2.1 2 0 0 2 2 2 1 PIN domain UPF0183 PF03676.14 OAG42137.1 - 6.8e-42 144.1 0.0 5.2e-26 91.9 0.0 3.1 2 2 0 2 2 2 2 Uncharacterised protein family (UPF0183) Kinesin PF00225.23 OAG42138.1 - 1.2e-106 356.4 0.5 1.2e-106 356.4 0.5 2.0 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 OAG42138.1 - 6e-23 81.4 0.0 4.6e-22 78.6 0.0 2.7 1 0 0 1 1 1 1 Microtubule binding Microtub_bind PF13931.6 OAG42138.1 - 1.1e-07 32.3 1.6 1.1e-07 32.3 1.6 4.6 4 1 1 5 5 5 1 Kinesin-associated microtubule-binding Apolipoprotein PF01442.18 OAG42138.1 - 3.9e-06 26.9 24.8 3.9e-06 26.9 24.8 4.0 1 1 2 3 3 3 1 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 OAG42138.1 - 0.0039 17.2 0.8 0.0039 17.2 0.8 5.5 4 3 2 6 6 6 2 Baculovirus polyhedron envelope protein, PEP, C terminus PB1 PF00564.24 OAG42138.1 - 0.11 12.4 1.0 0.37 10.7 0.1 2.4 2 0 0 2 2 2 0 PB1 domain DUF29 PF01724.16 OAG42138.1 - 0.66 10.2 13.8 1.3 9.2 6.3 3.2 1 1 0 2 2 2 0 Domain of unknown function DUF29 DUF1388 PF07142.12 OAG42139.1 - 0.01 15.8 5.7 0.029 14.3 1.8 2.5 1 1 1 2 2 2 2 Repeat of unknown function (DUF1388) Y_phosphatase PF00102.27 OAG42142.1 - 7.2e-50 169.7 0.0 6e-24 84.9 0.0 3.1 3 0 0 3 3 3 3 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 OAG42142.1 - 0.0065 16.5 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 OAG42142.1 - 0.027 14.6 0.0 0.075 13.2 0.0 1.8 1 0 0 1 1 1 0 Inositol hexakisphosphate DSPc PF00782.20 OAG42142.1 - 0.14 11.9 0.2 0.36 10.6 0.0 1.7 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain GATA PF00320.27 OAG42143.1 - 3e-15 55.5 5.3 5.9e-15 54.6 5.3 1.5 1 0 0 1 1 1 1 GATA zinc finger zinc_ribbon_9 PF14369.6 OAG42143.1 - 0.39 11.0 1.6 0.87 9.9 1.6 1.5 1 0 0 1 1 1 0 zinc-ribbon Acetyltransf_1 PF00583.25 OAG42144.1 - 0.12 12.6 0.0 0.21 11.8 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family FR47 PF08445.10 OAG42144.1 - 0.13 12.2 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Fungal_trans PF04082.18 OAG42145.1 - 7.4e-26 90.8 0.1 1.1e-25 90.1 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG42145.1 - 3e-07 30.4 9.0 5.1e-07 29.7 9.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Actin PF00022.19 OAG42146.1 - 6.8e-107 357.6 0.0 7.9e-106 354.1 0.0 2.3 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 OAG42146.1 - 0.17 10.7 0.0 0.6 8.9 0.0 1.8 1 1 0 1 1 1 0 MreB/Mbl protein His_Phos_1 PF00300.22 OAG42147.1 - 1.7e-28 99.7 0.0 2.3e-28 99.3 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Pap_E4 PF02711.14 OAG42148.1 - 0.022 15.7 0.8 0.022 15.7 0.8 2.8 4 0 0 4 4 4 0 E4 protein Miga PF10265.9 OAG42148.1 - 5.7 5.8 8.4 7.5 5.4 8.4 1.2 1 0 0 1 1 1 0 Mitoguardin SQS_PSY PF00494.19 OAG42149.1 - 1.7e-38 132.6 0.0 2.4e-38 132.1 0.0 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase SabA_adhesion PF18304.1 OAG42149.1 - 0.019 14.2 0.0 0.033 13.4 0.0 1.3 1 0 0 1 1 1 0 SabA N-terminal extracellular adhesion domain Peroxin-22 PF12827.7 OAG42149.1 - 0.032 14.2 0.1 0.1 12.5 0.0 1.9 2 0 0 2 2 2 0 Peroxisomal biogenesis protein family IL6Ra-bind PF09240.10 OAG42149.1 - 0.12 12.8 0.4 0.52 10.8 0.1 2.2 2 0 0 2 2 2 0 Interleukin-6 receptor alpha chain, binding DnaJ-X PF14308.6 OAG42150.1 - 1.8e-78 262.8 3.3 1.8e-78 262.8 3.3 3.5 3 1 1 4 4 4 1 X-domain of DnaJ-containing DnaJ PF00226.31 OAG42150.1 - 1.8e-24 85.7 0.3 6.2e-24 83.9 0.3 2.0 1 0 0 1 1 1 1 DnaJ domain Cytadhesin_P30 PF07271.11 OAG42150.1 - 0.1 12.2 0.1 0.2 11.2 0.1 1.5 1 0 0 1 1 1 0 Cytadhesin P30/P32 OrfB_IS605 PF01385.19 OAG42150.1 - 0.72 10.1 9.0 0.044 14.0 2.3 2.5 3 0 0 3 3 3 0 Probable transposase IMS PF00817.20 OAG42152.1 - 1.9e-43 148.0 1.0 3.3e-43 147.2 0.3 1.8 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.8 OAG42152.1 - 1.9e-14 54.3 0.3 4.2e-14 53.2 0.3 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 OAG42152.1 - 3.8e-06 26.9 0.0 1.3e-05 25.2 0.0 2.0 1 0 0 1 1 1 1 IMS family HHH motif EamA PF00892.20 OAG42153.1 - 1.4e-09 38.2 29.1 4.6e-06 26.8 3.4 2.6 3 0 0 3 3 3 2 EamA-like transporter family CSG2 PF16965.5 OAG42153.1 - 0.065 12.2 17.5 0.81 8.6 15.6 3.1 1 1 0 1 1 1 0 Ceramide synthase regulator DUF202 PF02656.15 OAG42153.1 - 0.16 12.4 14.3 0.059 13.8 2.6 3.7 2 1 1 3 3 3 0 Domain of unknown function (DUF202) FAM176 PF14851.6 OAG42153.1 - 0.32 10.6 4.9 0.33 10.6 0.4 2.3 2 0 0 2 2 2 0 FAM176 family TMEM234 PF10639.9 OAG42153.1 - 2.1 8.4 11.9 1.8 8.6 1.8 2.6 3 0 0 3 3 3 0 Putative transmembrane family 234 GMC_oxred_N PF00732.19 OAG42154.1 - 2.6e-53 181.3 0.0 3.8e-53 180.8 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAG42154.1 - 1e-35 123.4 0.0 1.8e-35 122.6 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 OAG42154.1 - 0.0049 17.1 0.1 0.019 15.2 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 OAG42154.1 - 0.033 13.2 0.1 0.053 12.6 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Aldo_ket_red PF00248.21 OAG42155.1 - 9.9e-54 182.5 0.0 1.1e-53 182.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Trans_coact PF16805.5 OAG42155.1 - 0.13 12.4 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 Phage late-transcription coactivator NIBRIN_BRCT_II PF16508.5 OAG42156.1 - 7.2e-31 107.0 0.0 2.4e-30 105.3 0.0 2.0 1 0 0 1 1 1 1 Second BRCT domain on Nijmegen syndrome breakage protein FHA PF00498.26 OAG42156.1 - 2.1e-10 40.8 0.1 6.5e-10 39.2 0.1 1.8 1 0 0 1 1 1 1 FHA domain RTT107_BRCT_5 PF16770.5 OAG42156.1 - 0.0031 17.4 0.5 0.0094 15.8 0.1 2.0 2 0 0 2 2 2 1 Regulator of Ty1 transposition protein 107 BRCT domain OAF PF14941.6 OAG42156.1 - 0.12 11.7 0.0 0.12 11.7 0.0 1.6 2 0 0 2 2 2 0 Transcriptional regulator, Out at first RPEL PF02755.15 OAG42157.1 - 1.3e-26 91.5 20.1 4.1e-09 35.8 0.6 3.4 3 0 0 3 3 3 3 RPEL repeat zf-H2C2_5 PF13909.6 OAG42157.1 - 1.1 9.1 6.3 19 5.1 0.3 3.1 3 0 0 3 3 3 0 C2H2-type zinc-finger domain GAGA PF09237.11 OAG42157.1 - 1.5 8.7 4.6 0.83 9.5 0.6 2.3 2 0 0 2 2 2 0 GAGA factor Translin PF01997.16 OAG42158.1 - 8.1e-65 218.6 0.1 9.5e-65 218.4 0.1 1.0 1 0 0 1 1 1 1 Translin family Mannosyl_trans PF05007.13 OAG42159.1 - 1.3e-75 254.6 15.1 1.8e-75 254.1 15.1 1.2 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) MFS_1 PF07690.16 OAG42161.1 - 5.2e-14 51.9 41.6 9.4e-13 47.8 41.9 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF2208 PF09973.9 OAG42161.1 - 0.091 12.4 3.6 2.2 7.8 0.0 3.0 2 1 1 3 3 3 0 Predicted membrane protein (DUF2208) COX8 PF02285.15 OAG42161.1 - 0.31 11.0 0.1 0.31 11.0 0.1 3.4 4 0 0 4 4 4 0 Cytochrome oxidase c subunit VIII Bac_rhodopsin PF01036.18 OAG42162.1 - 7e-51 172.9 19.8 8.8e-51 172.6 19.8 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein MerC PF03203.14 OAG42162.1 - 0.0032 17.9 11.1 0.0073 16.8 5.4 2.4 2 0 0 2 2 2 1 MerC mercury resistance protein Heliorhodopsin PF18761.1 OAG42162.1 - 0.0047 16.3 10.3 0.0074 15.6 10.0 1.6 1 1 0 1 1 1 1 Heliorhodopsin DUF1772 PF08592.11 OAG42162.1 - 0.47 10.8 14.3 0.98 9.7 4.3 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) tRNA-synt_1 PF00133.22 OAG42163.1 - 1.8e-149 498.8 0.0 2.5e-149 498.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 OAG42163.1 - 6.2e-20 71.7 0.2 1.1e-19 70.9 0.2 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 OAG42163.1 - 9.9e-20 70.6 0.0 3e-12 46.0 0.0 3.5 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 OAG42163.1 - 0.016 14.5 0.0 3 7.1 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain zf-FPG_IleRS PF06827.14 OAG42163.1 - 0.024 14.5 3.9 0.074 12.9 3.9 1.9 1 1 0 1 1 1 0 Zinc finger found in FPG and IleRS tRNA-synt_1_2 PF13603.6 OAG42163.1 - 0.15 11.6 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 Leucyl-tRNA synthetase, Domain 2 Rhodanese PF00581.20 OAG42164.1 - 3.3e-14 53.3 0.0 2e-08 34.7 0.0 2.3 2 0 0 2 2 2 2 Rhodanese-like domain Peptidase_M24 PF00557.24 OAG42165.1 - 4.6e-50 170.2 0.1 5.6e-50 169.9 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 OAG42165.1 - 1.6e-18 66.7 8.5 3.8e-18 65.5 8.5 1.7 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 OAG42165.1 - 5.3e-05 23.2 5.5 0.00015 21.7 5.5 1.8 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.16 OAG42165.1 - 0.083 12.8 4.4 0.22 11.4 4.4 1.8 1 0 0 1 1 1 0 HIT zinc finger EF-hand_1 PF00036.32 OAG42166.1 - 5.1e-13 47.6 4.2 2.5e-05 23.5 0.1 4.0 4 0 0 4 4 4 2 EF hand ZZ PF00569.17 OAG42166.1 - 3e-12 46.1 4.9 5.1e-12 45.4 4.9 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type EF-hand_7 PF13499.6 OAG42166.1 - 5.9e-10 39.4 3.9 0.00016 22.0 0.7 4.1 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_6 PF13405.6 OAG42166.1 - 3e-09 36.1 4.1 0.00037 20.2 0.5 3.8 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 OAG42166.1 - 0.00063 19.5 4.9 0.73 9.7 0.1 3.9 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 OAG42166.1 - 0.00077 18.9 6.9 1.2 8.7 0.0 4.4 4 0 0 4 4 4 2 EF hand C1_2 PF03107.16 OAG42166.1 - 0.034 14.5 5.1 0.069 13.5 5.1 1.5 1 0 0 1 1 1 0 C1 domain CAML PF14963.6 OAG42166.1 - 0.08 13.1 0.2 0.16 12.1 0.2 1.4 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand DUF3405 PF11885.8 OAG42166.1 - 0.13 10.9 0.2 0.19 10.3 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3405) zf-B_box PF00643.24 OAG42166.1 - 0.24 11.6 5.7 0.42 10.8 5.7 1.3 1 0 0 1 1 1 0 B-box zinc finger WD40 PF00400.32 OAG42168.1 - 6e-15 55.4 13.1 0.00016 22.4 0.0 6.6 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG42168.1 - 8.8e-07 29.1 0.0 0.22 11.8 0.0 4.6 4 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain MutS_V PF00488.21 OAG42169.1 - 5.8e-63 212.3 0.2 1e-62 211.5 0.2 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 OAG42169.1 - 6.7e-29 101.5 0.5 1.6e-28 100.2 0.5 1.7 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.18 OAG42169.1 - 4e-11 43.1 1.0 1.1e-10 41.7 0.9 1.9 2 0 0 2 2 2 1 MutS family domain IV MutS_II PF05188.17 OAG42169.1 - 8.3e-10 39.1 0.0 2.2e-09 37.7 0.0 1.7 1 0 0 1 1 1 1 MutS domain II AAA_30 PF13604.6 OAG42169.1 - 0.011 15.5 0.0 0.027 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_27 PF13514.6 OAG42169.1 - 0.055 13.1 0.0 0.19 11.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain DUF3213 PF11491.8 OAG42169.1 - 0.11 12.7 0.1 0.36 11.0 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) WD40 PF00400.32 OAG42170.1 - 2.3e-65 214.9 32.8 2.9e-12 46.9 0.6 9.3 9 0 0 9 9 9 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG42170.1 - 9.2e-25 86.8 4.1 3.8e-06 27.1 0.0 6.7 2 2 4 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OAG42170.1 - 7.5e-13 48.1 4.2 0.014 14.4 1.7 6.3 3 3 4 7 7 7 4 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 OAG42170.1 - 1.6e-06 27.1 9.2 0.36 9.4 1.3 5.8 4 2 1 6 6 6 2 Nucleoporin Nup120/160 eIF2A PF08662.11 OAG42170.1 - 9.1e-06 25.7 0.0 0.071 13.0 0.0 2.6 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A NLE PF08154.12 OAG42170.1 - 2e-05 25.0 0.1 4.2e-05 24.0 0.1 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain IKI3 PF04762.12 OAG42170.1 - 5.7e-05 21.3 0.1 0.23 9.4 0.0 3.1 2 1 1 3 3 3 3 IKI3 family Nbas_N PF15492.6 OAG42170.1 - 0.00044 19.7 0.8 4.9 6.4 0.0 3.8 4 0 0 4 4 4 2 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.12 OAG42170.1 - 0.021 14.7 3.0 1.4 8.9 0.0 3.6 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat FAD_binding_9 PF08021.11 OAG42170.1 - 0.067 13.4 0.0 0.22 11.8 0.0 1.8 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain Nucleoporin_N PF08801.11 OAG42170.1 - 0.084 11.6 2.8 1.5 7.5 2.8 3.1 1 1 0 1 1 1 0 Nup133 N terminal like DUF1513 PF07433.11 OAG42170.1 - 0.09 11.8 0.1 0.88 8.6 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1513) Proteasome_A_N PF10584.9 OAG42170.1 - 0.2 11.4 0.5 20 5.0 0.0 3.2 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature PALB2_WD40 PF16756.5 OAG42170.1 - 0.26 10.2 4.0 4.8 6.0 0.2 3.3 3 1 1 4 4 4 0 Partner and localizer of BRCA2 WD40 domain Cytochrom_C1 PF02167.15 OAG42171.1 - 1e-93 313.1 0.0 1.3e-93 312.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 OAG42171.1 - 0.015 15.6 0.0 0.032 14.6 0.0 1.7 1 0 0 1 1 1 0 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 OAG42171.1 - 0.023 15.8 0.0 0.11 13.7 0.0 2.1 2 0 0 2 2 2 0 Cytochrome c RSN1_7TM PF02714.15 OAG42172.1 - 2.2e-80 269.9 18.6 2.2e-80 269.9 18.6 2.0 3 0 0 3 3 3 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 OAG42172.1 - 2.2e-41 142.0 0.0 3.3e-41 141.5 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 OAG42172.1 - 9.9e-37 126.1 1.4 9.9e-37 126.1 1.4 2.6 2 1 0 2 2 2 1 Late exocytosis, associated with Golgi transport Phage_holin_4_1 PF05105.12 OAG42172.1 - 0.032 14.4 1.1 0.13 12.4 1.1 2.0 1 0 0 1 1 1 0 Bacteriophage holin family F-box PF00646.33 OAG42173.1 - 1.5e-06 28.0 0.0 0.065 13.1 0.0 2.5 2 0 0 2 2 2 2 F-box domain F-box-like PF12937.7 OAG42173.1 - 3.8e-06 26.7 0.9 0.017 15.0 0.1 2.7 2 0 0 2 2 2 2 F-box-like F-box_5 PF18511.1 OAG42173.1 - 0.023 14.3 0.9 2.2 7.9 0.2 2.5 2 0 0 2 2 2 0 F-box Aminotran_3 PF00202.21 OAG42174.1 - 1.4e-31 109.6 0.0 1.6e-20 73.2 0.0 4.2 4 1 0 4 4 4 2 Aminotransferase class-III AAA_26 PF13500.6 OAG42174.1 - 2.2e-21 76.6 0.0 3.7e-21 75.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 OAG42174.1 - 0.038 14.0 0.0 0.12 12.4 0.0 1.8 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Aminotran_1_2 PF00155.21 OAG42175.1 - 3.2e-44 151.6 0.0 3.7e-44 151.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 OAG42175.1 - 3.8e-09 35.6 0.0 6.2e-09 34.9 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 OAG42175.1 - 0.013 14.5 0.0 0.054 12.4 0.0 1.9 3 0 0 3 3 3 0 Aminotransferase class-V Beta_elim_lyase PF01212.21 OAG42175.1 - 0.063 12.5 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Aminotran_3 PF00202.21 OAG42175.1 - 0.21 10.2 0.0 0.26 9.9 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-III adh_short PF00106.25 OAG42176.1 - 2.2e-23 82.7 0.0 5.2e-22 78.3 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG42176.1 - 4.4e-14 52.6 0.0 3.8e-13 49.5 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG42176.1 - 8.9e-09 35.5 0.0 1.5e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG42176.1 - 8.6e-05 22.1 0.0 0.00012 21.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 OAG42176.1 - 0.0013 17.9 0.0 0.0023 17.1 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Methyltransf_25 PF13649.6 OAG42176.1 - 0.097 13.4 0.0 0.23 12.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Fungal_trans_2 PF11951.8 OAG42177.1 - 1.8e-17 63.3 2.8 3.6e-11 42.5 0.3 2.0 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG42177.1 - 5.6e-10 39.2 7.8 8.6e-10 38.6 7.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ecm29 PF13001.7 OAG42178.1 - 6.8e-127 424.2 2.6 2.1e-126 422.5 0.1 2.9 3 0 0 3 3 3 1 Proteasome stabiliser Vac14_Fab1_bd PF12755.7 OAG42178.1 - 0.00018 22.0 0.4 0.89 10.2 0.2 5.1 5 1 0 5 5 5 1 Vacuolar 14 Fab1-binding region HEAT PF02985.22 OAG42178.1 - 0.012 15.8 9.5 19 5.9 0.0 7.8 9 0 0 9 9 9 0 HEAT repeat RIX1 PF08167.12 OAG42178.1 - 0.012 15.3 0.0 0.012 15.3 0.0 4.1 6 0 0 6 6 6 0 rRNA processing/ribosome biogenesis Nipped-B_C PF12830.7 OAG42178.1 - 0.16 11.9 1.9 14 5.5 0.0 3.6 4 0 0 4 4 4 0 Sister chromatid cohesion C-terminus HisG PF01634.18 OAG42179.1 - 2.8e-59 199.7 0.1 4.4e-59 199.0 0.1 1.3 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 OAG42179.1 - 5.8e-29 100.1 1.3 7.7e-29 99.7 0.3 1.8 2 0 0 2 2 2 1 HisG, C-terminal domain NMT1 PF09084.11 OAG42179.1 - 0.0018 18.3 0.1 0.0034 17.4 0.1 1.4 1 1 0 1 1 1 1 NMT1/THI5 like Fcf1 PF04900.12 OAG42180.1 - 2.6e-38 130.4 0.3 4.4e-38 129.7 0.3 1.4 1 0 0 1 1 1 1 Fcf1 PIN_9 PF18477.1 OAG42180.1 - 7.5e-13 48.8 0.3 3.5e-12 46.7 0.1 2.0 2 0 0 2 2 2 1 PIN like domain DUF4706 PF15797.5 OAG42180.1 - 0.1 13.1 0.0 0.24 11.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4706) ATP11 PF06644.11 OAG42182.1 - 2.4e-86 289.9 0.0 2.9e-86 289.7 0.0 1.0 1 0 0 1 1 1 1 ATP11 protein CAP_N PF01213.19 OAG42182.1 - 10 5.5 12.3 18 4.6 12.3 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Hydrolase_4 PF12146.8 OAG42183.1 - 6.2e-15 55.1 0.0 1.1e-09 37.9 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OAG42183.1 - 1.6e-12 47.7 0.1 1.3e-07 31.6 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold AXE1 PF05448.12 OAG42183.1 - 3e-08 32.7 0.0 4.9e-05 22.1 0.0 3.1 1 1 1 2 2 2 1 Acetyl xylan esterase (AXE1) Abhydrolase_6 PF12697.7 OAG42183.1 - 3.3e-07 31.1 0.0 2.1e-06 28.5 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.11 OAG42183.1 - 8.5e-05 22.6 0.0 0.0039 17.1 0.0 2.3 1 1 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal FSH1 PF03959.13 OAG42183.1 - 9.9e-05 22.1 0.0 0.00017 21.3 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.13 OAG42183.1 - 0.0006 19.7 0.1 0.0012 18.7 0.1 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 OAG42183.1 - 0.00079 19.1 0.0 1 8.9 0.0 2.3 2 0 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 OAG42183.1 - 0.002 17.6 0.0 0.0035 16.8 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family LIDHydrolase PF10230.9 OAG42183.1 - 0.0045 16.6 0.0 0.11 12.0 0.1 2.1 1 1 1 2 2 2 1 Lipid-droplet associated hydrolase DLH PF01738.18 OAG42183.1 - 0.013 15.0 0.0 0.14 11.7 0.0 2.1 1 1 0 1 1 1 0 Dienelactone hydrolase family DUF818 PF05677.12 OAG42183.1 - 0.063 12.2 0.0 0.081 11.9 0.0 1.1 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) Lipase_3 PF01764.25 OAG42183.1 - 0.14 12.0 0.0 0.32 10.9 0.0 1.5 1 1 0 1 1 1 0 Lipase (class 3) UPF0227 PF05728.12 OAG42183.1 - 0.14 12.0 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Abhydrolase_4 PF08386.10 OAG42183.1 - 0.2 11.8 0.0 0.42 10.8 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein Acyl_transf_2 PF02273.15 OAG42183.1 - 0.24 10.6 0.0 0.57 9.4 0.0 1.5 2 0 0 2 2 2 0 Acyl transferase Proteasome PF00227.26 OAG42184.1 - 3.4e-47 160.4 0.5 3.9e-47 160.2 0.5 1.0 1 0 0 1 1 1 1 Proteasome subunit Cyclin PF08613.11 OAG42185.1 - 1.1e-39 136.4 2.4 2.3e-24 86.6 0.1 2.9 3 0 0 3 3 3 2 Cyclin SNF2_N PF00176.23 OAG42186.1 - 5.7e-52 176.6 1.3 1.2e-50 172.3 0.1 2.6 2 1 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OAG42186.1 - 2e-17 63.5 0.0 2.3e-16 60.1 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG42186.1 - 4e-06 26.9 0.0 2.2e-05 24.5 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.25 OAG42186.1 - 3.7e-05 23.5 7.8 3.7e-05 23.5 7.8 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OAG42186.1 - 0.0048 16.7 7.9 0.0048 16.7 7.9 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) AAA_34 PF13872.6 OAG42186.1 - 0.005 15.8 0.1 0.014 14.3 0.0 1.7 2 0 0 2 2 2 1 P-loop containing NTP hydrolase pore-1 ERCC3_RAD25_C PF16203.5 OAG42186.1 - 0.019 14.1 0.0 0.04 13.1 0.0 1.4 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Zn_Tnp_IS91 PF14319.6 OAG42186.1 - 1.7 8.7 14.9 0.29 11.2 3.0 2.6 2 0 0 2 2 2 0 Transposase zinc-binding domain LRR_4 PF12799.7 OAG42187.1 - 0.0038 17.6 4.5 16 6.1 0.1 5.2 3 1 2 5 5 5 2 Leucine Rich repeats (2 copies) INCENP_N PF12178.8 OAG42187.1 - 0.024 14.6 0.0 0.41 10.7 0.0 2.8 2 0 0 2 2 2 0 Chromosome passenger complex (CPC) protein INCENP N terminal FYVE PF01363.21 OAG42187.1 - 0.031 14.4 1.0 0.12 12.5 1.0 2.0 1 1 0 1 1 1 0 FYVE zinc finger DUF4428 PF14471.6 OAG42187.1 - 0.091 12.7 1.4 0.26 11.2 1.4 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) LRR_8 PF13855.6 OAG42187.1 - 0.17 11.7 2.0 1.3 8.8 0.8 3.2 1 1 1 2 2 2 0 Leucine rich repeat Vps39_2 PF10367.9 OAG42187.1 - 0.55 10.7 3.0 0.48 10.9 0.4 2.4 2 1 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 ATP-synt_B PF00430.18 OAG42187.1 - 8.4 6.5 18.3 4.2 7.4 13.0 2.2 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) MutS_V PF00488.21 OAG42188.1 - 2.2e-74 249.6 0.2 5.9e-74 248.2 0.2 1.8 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 OAG42188.1 - 2.2e-37 129.1 0.4 4.9e-37 128.0 0.4 1.6 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 OAG42188.1 - 1.6e-29 102.4 0.1 6.7e-29 100.4 0.0 2.1 2 0 0 2 2 2 1 MutS domain I MutS_II PF05188.17 OAG42188.1 - 4.5e-09 36.7 0.0 1.2e-08 35.3 0.0 1.8 1 0 0 1 1 1 1 MutS domain II DUF4911 PF16256.5 OAG42188.1 - 0.0028 17.6 0.0 0.015 15.3 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4911) MutS_IV PF05190.18 OAG42188.1 - 0.011 16.0 0.0 0.032 14.6 0.0 1.8 1 0 0 1 1 1 0 MutS family domain IV FAD_binding_3 PF01494.19 OAG42189.1 - 4.5e-24 85.3 0.0 2e-23 83.2 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAG42189.1 - 0.00012 21.8 0.1 0.068 12.7 0.0 2.3 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 OAG42189.1 - 0.0084 16.1 0.0 0.018 15.1 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding SE PF08491.10 OAG42189.1 - 0.038 13.1 0.0 0.33 10.0 0.0 2.0 2 0 0 2 2 2 0 Squalene epoxidase Pyr_redox_2 PF07992.14 OAG42189.1 - 0.078 12.2 0.0 7.9 5.6 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAG42189.1 - 0.14 12.7 0.0 18 6.0 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ubiquitin PF00240.23 OAG42191.1 - 0.069 12.9 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin family Pkinase PF00069.25 OAG42192.1 - 1.7e-64 217.7 0.0 2.3e-64 217.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG42192.1 - 1.5e-36 126.0 0.0 2e-36 125.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAG42192.1 - 0.0018 17.7 0.0 0.0026 17.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OAG42192.1 - 0.042 12.6 0.0 0.13 11.0 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase APH PF01636.23 OAG42192.1 - 0.064 13.2 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family IGR PF09597.10 OAG42193.1 - 1.6e-26 92.2 0.9 2.7e-26 91.4 0.9 1.4 1 0 0 1 1 1 1 IGR protein motif Kinesin PF00225.23 OAG42194.1 - 5.4e-95 318.1 0.0 1.3e-94 316.9 0.0 1.6 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 OAG42194.1 - 1.3e-22 80.4 0.0 7.2e-22 77.9 0.0 2.1 2 0 0 2 2 2 1 Microtubule binding DUF4407 PF14362.6 OAG42194.1 - 0.15 11.4 17.1 0.27 10.5 6.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Spc7 PF08317.11 OAG42194.1 - 0.29 10.0 17.0 1 8.2 5.7 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein FapA PF03961.13 OAG42194.1 - 2.5 6.6 7.0 1.7 7.2 1.7 2.3 2 0 0 2 2 2 0 Flagellar Assembly Protein A Lebercilin PF15619.6 OAG42194.1 - 4.9 6.8 24.7 0.27 10.9 0.9 3.5 3 1 0 4 4 4 0 Ciliary protein causing Leber congenital amaurosis disease Glyco_transf_11 PF01531.16 OAG42195.1 - 0.13 11.4 0.0 0.53 9.5 0.0 1.8 1 1 0 2 2 2 0 Glycosyl transferase family 11 AMP-binding PF00501.28 OAG42196.1 - 4.4e-59 200.2 0.0 5.8e-59 199.8 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG42196.1 - 7e-10 39.8 0.1 1.4e-09 38.8 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain YL1_C PF08265.11 OAG42196.1 - 0.02 14.6 0.2 0.052 13.3 0.2 1.6 1 0 0 1 1 1 0 YL1 nuclear protein C-terminal domain Eisosome1 PF12757.7 OAG42197.1 - 3.8e-39 133.8 14.6 3.8e-39 133.8 14.6 4.6 4 1 1 5 5 5 1 Eisosome protein 1 TSP9 PF11493.8 OAG42197.1 - 0.053 14.2 0.4 0.44 11.2 0.4 2.7 1 0 0 1 1 1 0 Thylakoid soluble phosphoprotein TSP9 Y_phosphatase3 PF13350.6 OAG42198.1 - 1.3e-40 139.8 0.0 2.4e-40 138.9 0.0 1.4 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 OAG42198.1 - 2.2e-06 27.3 0.0 6.7e-06 25.8 0.0 1.8 2 0 0 2 2 2 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 OAG42198.1 - 0.034 13.7 0.0 0.055 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DSPc PF00782.20 OAG42198.1 - 0.16 11.8 0.0 1.3 8.9 0.0 2.2 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain Frag1 PF10277.9 OAG42199.1 - 7.4e-47 159.7 19.8 8.8e-47 159.4 19.8 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family EMP70 PF02990.16 OAG42199.1 - 0.00031 19.6 1.2 0.00046 19.0 1.2 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 60KD_IMP PF02096.20 OAG42199.1 - 0.096 12.6 0.6 0.17 11.7 0.6 1.4 1 0 0 1 1 1 0 60Kd inner membrane protein DUF973 PF06157.11 OAG42199.1 - 0.42 9.6 3.9 0.35 9.9 2.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF973) DUF2964 PF11177.8 OAG42199.1 - 6.9 7.0 8.3 0.87 9.8 0.8 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2964) DUF3533 PF12051.8 OAG42200.1 - 6.7e-69 232.6 3.8 8e-69 232.4 3.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) Pkinase PF00069.25 OAG42201.1 - 1.2e-05 24.8 0.0 3.9e-05 23.1 0.0 1.9 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG42201.1 - 0.00037 19.9 0.0 0.0076 15.6 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Death PF00531.22 OAG42201.1 - 0.16 12.1 1.5 3.9 7.7 0.0 2.9 3 0 0 3 3 3 0 Death domain Ank_2 PF12796.7 OAG42202.1 - 9.5e-27 93.4 0.0 1.1e-09 38.7 0.0 5.7 3 1 3 6 6 6 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAG42202.1 - 5.3e-22 77.9 2.6 8.8e-08 32.6 0.0 6.8 3 3 4 7 7 7 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 OAG42202.1 - 3.4e-21 75.0 1.2 8.7e-09 35.5 0.0 4.9 4 0 0 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG42202.1 - 2e-20 70.7 2.6 1e-05 25.5 0.1 7.7 8 0 0 8 8 8 4 Ankyrin repeat Ank PF00023.30 OAG42202.1 - 8e-20 70.3 2.8 9.8e-05 22.6 0.3 6.9 6 0 0 6 6 6 4 Ankyrin repeat Pkinase PF00069.25 OAG42202.1 - 2.4e-16 59.9 0.0 4.4e-16 59.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG42202.1 - 2.4e-08 33.6 0.0 1.3e-07 31.1 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OAG42202.1 - 0.1 12.0 0.0 0.24 10.7 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Aldo_ket_red PF00248.21 OAG42203.1 - 1.1e-49 169.3 0.1 1.3e-49 169.0 0.1 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family LpxC PF03331.13 OAG42203.1 - 0.0076 15.8 0.0 0.012 15.1 0.0 1.2 1 0 0 1 1 1 1 UDP-3-O-acyl N-acetylglycosamine deacetylase Cupin_2 PF07883.11 OAG42204.1 - 2.9e-12 46.1 0.5 4.5e-12 45.5 0.5 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 OAG42204.1 - 2.1e-07 30.7 0.1 3.9e-07 29.8 0.1 1.4 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.19 OAG42204.1 - 8.1e-07 29.0 0.7 1.3e-06 28.4 0.7 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_6 PF12852.7 OAG42204.1 - 2.2e-05 24.3 0.1 2.9e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.12 OAG42204.1 - 0.0017 18.0 0.3 0.0033 17.1 0.3 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF861) ARD PF03079.14 OAG42204.1 - 0.0053 17.0 0.3 0.0091 16.2 0.3 1.3 1 0 0 1 1 1 1 ARD/ARD' family ADH_N PF08240.12 OAG42205.1 - 4.5e-20 71.6 5.1 7.4e-20 70.9 5.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG42205.1 - 9.1e-19 67.7 0.0 2.2e-18 66.5 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAG42205.1 - 4.5e-06 27.7 0.0 7.6e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 OAG42205.1 - 0.0097 15.3 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 OAG42205.1 - 0.04 13.2 0.0 0.088 12.1 0.0 1.5 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain KR PF08659.10 OAG42205.1 - 0.15 12.0 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 KR domain DUF3425 PF11905.8 OAG42206.1 - 2.4e-20 72.8 0.0 5.1e-20 71.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) DnaJ PF00226.31 OAG42207.1 - 1.1e-20 73.4 3.0 1.1e-20 73.4 3.0 1.7 2 0 0 2 2 2 1 DnaJ domain SARAF PF06682.12 OAG42207.1 - 0.0099 15.6 0.7 0.087 12.5 0.7 2.0 1 1 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis DUF456 PF04306.13 OAG42207.1 - 0.015 15.6 0.4 0.022 15.1 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF456) DUF1269 PF06897.12 OAG42207.1 - 0.017 15.4 2.3 0.029 14.6 2.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) Gly-zipper_YMGG PF13441.6 OAG42207.1 - 0.023 14.4 7.7 0.037 13.8 7.7 1.3 1 0 0 1 1 1 0 YMGG-like Gly-zipper Gly-zipper_Omp PF13488.6 OAG42207.1 - 0.082 12.9 8.3 0.13 12.3 8.3 1.3 1 0 0 1 1 1 0 Glycine zipper PT-VENN PF04829.13 OAG42207.1 - 0.83 9.8 4.9 0.63 10.2 2.3 1.9 2 0 0 2 2 2 0 Pre-toxin domain with VENN motif Rick_17kDa_Anti PF05433.15 OAG42207.1 - 2.4 8.1 12.9 4.1 7.4 12.9 1.3 1 0 0 1 1 1 0 Glycine zipper 2TM domain PRA1 PF03208.19 OAG42210.1 - 8.2e-37 126.0 0.6 1e-36 125.7 0.6 1.1 1 0 0 1 1 1 1 PRA1 family protein DnaJ PF00226.31 OAG42211.1 - 2.2e-07 30.9 0.0 4.9e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain Cornichon PF03311.14 OAG42213.1 - 2.6e-41 140.8 7.9 3.1e-41 140.5 7.9 1.0 1 0 0 1 1 1 1 Cornichon protein WD40 PF00400.32 OAG42214.1 - 1.1e-26 92.6 5.4 1.8e-06 28.6 0.0 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG42214.1 - 4.6e-12 46.1 0.0 0.026 14.8 0.0 4.7 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 OAG42214.1 - 5.8e-06 26.1 0.1 1.9e-05 24.4 0.0 1.9 2 0 0 2 2 2 1 PQQ-like domain Cytochrom_D1 PF02239.16 OAG42214.1 - 0.008 14.8 0.0 0.018 13.6 0.0 1.5 1 0 0 1 1 1 1 Cytochrome D1 heme domain Nup160 PF11715.8 OAG42214.1 - 0.15 10.7 0.0 0.57 8.7 0.0 1.8 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Sod_Fe_C PF02777.18 OAG42215.1 - 5.7e-18 65.0 0.1 9.8e-08 32.1 0.4 2.4 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain Lustrin_cystein PF14625.6 OAG42216.1 - 0.054 13.9 16.4 0.58 10.6 4.7 2.8 2 0 0 2 2 2 0 Lustrin, cysteine-rich repeated domain CS PF04969.16 OAG42217.1 - 9.7e-17 61.8 0.5 1.9e-16 60.8 0.1 1.7 2 0 0 2 2 2 1 CS domain Melibiase_2 PF16499.5 OAG42218.1 - 1.2e-52 178.9 0.8 8.5e-37 126.9 0.3 2.2 2 0 0 2 2 2 2 Alpha galactosidase A Melibiase_C PF17801.1 OAG42218.1 - 1.7e-09 37.6 0.9 2.1e-07 30.9 1.0 2.6 2 0 0 2 2 2 2 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 OAG42218.1 - 0.0019 17.2 0.0 0.0032 16.5 0.0 1.2 1 0 0 1 1 1 1 Melibiase UbiA PF01040.18 OAG42219.1 - 2.3e-57 194.2 12.7 3.6e-57 193.6 12.7 1.3 1 0 0 1 1 1 1 UbiA prenyltransferase family Med8 PF10232.9 OAG42220.1 - 9.8e-43 146.4 4.1 1.1e-42 146.2 4.1 1.0 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 Astro_capsid_p PF12226.8 OAG42220.1 - 0.16 11.1 14.3 0.047 12.8 10.8 1.8 2 0 0 2 2 2 0 Turkey astrovirus capsid protein Pox_Ag35 PF03286.14 OAG42220.1 - 0.61 9.8 5.3 1.4 8.6 5.3 1.6 1 0 0 1 1 1 0 Pox virus Ag35 surface protein F-box-like_2 PF13013.6 OAG42221.1 - 0.06 13.3 0.0 0.48 10.4 0.0 2.2 2 0 0 2 2 2 0 F-box-like domain Acyl-CoA_dh_1 PF00441.24 OAG42222.1 - 3.2e-33 115.0 0.3 5.5e-33 114.3 0.1 1.5 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 OAG42222.1 - 5.6e-19 68.1 0.4 9.9e-19 67.4 0.4 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.28 OAG42222.1 - 4.2e-15 55.7 0.3 3.1e-12 46.5 0.1 3.0 3 0 0 3 3 3 2 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.16 OAG42222.1 - 6.1e-11 43.0 0.0 1.9e-10 41.4 0.0 1.9 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 OAG42222.1 - 9.4e-06 25.9 0.0 2.6e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Amidase PF01425.21 OAG42223.1 - 1e-74 252.1 0.1 2.1e-74 251.1 0.1 1.5 1 1 0 1 1 1 1 Amidase Adhesin_P1 PF03257.13 OAG42223.1 - 0.015 15.8 0.0 0.074 13.6 0.0 2.2 1 0 0 1 1 1 0 Mycoplasma adhesin P1 PIG-S PF10510.9 OAG42224.1 - 1.3e-140 469.7 0.0 1.5e-140 469.5 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein Polyketide_cyc PF03364.20 OAG42225.1 - 7.3e-22 78.0 0.0 9.4e-22 77.6 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 OAG42225.1 - 8.5e-07 29.3 0.1 1.1e-06 28.9 0.1 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport SMN PF06003.12 OAG42226.1 - 6.7e-06 25.5 1.5 0.023 14.0 0.4 2.2 2 0 0 2 2 2 2 Survival motor neuron protein (SMN) DUF1631 PF07793.11 OAG42226.1 - 1.7 6.9 9.7 1.9 6.8 9.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) Nefa_Nip30_N PF10187.9 OAG42228.1 - 8e-32 109.7 3.1 8e-32 109.7 3.1 2.2 2 1 0 2 2 2 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 Pap_E4 PF02711.14 OAG42228.1 - 0.02 15.8 0.4 0.052 14.5 0.4 1.7 1 0 0 1 1 1 0 E4 protein DUF572 PF04502.13 OAG42228.1 - 0.078 12.6 11.6 0.094 12.3 11.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) WBS_methylT PF12589.8 OAG42228.1 - 1.9 9.3 10.2 3.2 8.6 7.6 2.4 1 1 1 2 2 2 0 Methyltransferase involved in Williams-Beuren syndrome DUF4407 PF14362.6 OAG42228.1 - 3.7 6.8 13.1 4.8 6.4 13.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Aldo_ket_red PF00248.21 OAG42229.1 - 3.8e-47 160.9 0.0 8.6e-46 156.5 0.0 2.3 1 1 0 1 1 1 1 Aldo/keto reductase family Fungal_trans PF04082.18 OAG42229.1 - 6.8e-21 74.5 0.1 1.2e-20 73.7 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG42229.1 - 5.2e-09 36.1 12.5 9.8e-09 35.2 12.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.32 OAG42230.1 - 1.3e-22 79.6 11.0 7.3e-05 23.5 0.2 7.0 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG42230.1 - 6.8e-14 51.9 1.1 0.0064 16.8 0.1 6.1 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OAG42230.1 - 4.9e-06 26.6 0.0 0.0021 18.0 0.0 2.8 2 2 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 OAG42230.1 - 2.2e-05 23.2 0.0 0.0009 17.9 0.0 2.2 2 0 0 2 2 2 2 Cytochrome D1 heme domain PD40 PF07676.12 OAG42230.1 - 0.068 13.1 2.1 4.1 7.5 0.3 3.5 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Nup160 PF11715.8 OAG42230.1 - 0.077 11.6 0.4 0.39 9.3 0.2 1.9 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Coatomer_WDAD PF04053.14 OAG42230.1 - 0.093 11.8 0.0 8.1 5.4 0.0 2.3 2 0 0 2 2 2 0 Coatomer WD associated region Sulfatase PF00884.23 OAG42231.1 - 3.3e-62 210.7 1.5 5e-62 210.0 1.5 1.3 1 0 0 1 1 1 1 Sulfatase DUF4976 PF16347.5 OAG42231.1 - 0.00013 22.2 0.0 0.00025 21.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4976) Phosphodiest PF01663.22 OAG42231.1 - 0.00029 20.5 0.3 0.33 10.5 0.3 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 OAG42231.1 - 0.0015 17.2 0.0 0.12 11.0 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF229) DUF1657 PF07870.11 OAG42232.1 - 0.0083 16.0 1.7 0.015 15.1 1.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1657) DUF4255 PF14065.6 OAG42232.1 - 0.021 14.5 0.0 0.026 14.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4255) DUF5556 PF17711.1 OAG42232.1 - 0.031 14.2 0.0 0.038 13.9 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5556) ExbD PF02472.16 OAG42232.1 - 0.095 12.9 0.0 0.26 11.4 0.0 1.7 1 1 0 1 1 1 0 Biopolymer transport protein ExbD/TolR Aminotran_4 PF01063.19 OAG42233.1 - 4.3e-46 157.6 0.0 5.1e-46 157.3 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV DUF3176 PF11374.8 OAG42234.1 - 1.4e-06 28.5 9.4 4.5e-06 26.8 9.4 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) PAP2 PF01569.21 OAG42235.1 - 2e-27 95.6 2.8 4.9e-27 94.3 1.5 2.1 2 0 0 2 2 2 1 PAP2 superfamily Aldo_ket_red PF00248.21 OAG42236.1 - 1.1e-49 169.2 0.0 1.7e-49 168.6 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family MARVEL PF01284.23 OAG42237.1 - 0.15 12.1 19.0 0.28 11.2 18.3 1.8 1 1 0 1 1 1 0 Membrane-associating domain DUF2070 PF09843.9 OAG42237.1 - 0.76 8.0 3.5 1 7.6 3.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) MFS_1 PF07690.16 OAG42238.1 - 1.4e-35 122.9 52.2 3.4e-34 118.3 51.9 2.1 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1418 PF07214.12 OAG42238.1 - 0.054 13.3 0.7 0.27 11.1 0.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1418) DUF4231 PF14015.6 OAG42238.1 - 1.2 9.7 4.0 1.4 9.4 0.1 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) ATP_synth_reg PF14960.6 OAG42238.1 - 1.7 8.2 4.1 2.3 7.8 0.0 2.9 3 0 0 3 3 3 0 ATP synthase regulation peroxidase PF00141.23 OAG42240.1 - 3.1e-43 148.1 0.0 4.5e-43 147.6 0.0 1.2 1 0 0 1 1 1 1 Peroxidase CFEM PF05730.11 OAG42241.1 - 5.5e-12 45.6 8.4 1e-11 44.7 8.4 1.4 1 0 0 1 1 1 1 CFEM domain VSG_B PF13206.6 OAG42241.1 - 4.9 6.3 6.8 7 5.8 6.8 1.1 1 0 0 1 1 1 0 Trypanosomal VSG domain Aldo_ket_red PF00248.21 OAG42242.1 - 1.8e-48 165.2 0.0 2.1e-48 165.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Tachystatin_A PF11406.8 OAG42242.1 - 0.0032 17.5 0.1 0.0073 16.4 0.1 1.5 1 0 0 1 1 1 1 Antimicrobial peptide tachystatin A TRI12 PF06609.13 OAG42243.1 - 7.3e-51 173.3 23.5 9.6e-51 172.9 23.5 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG42243.1 - 2.1e-19 69.7 46.0 2.1e-19 69.7 46.0 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily Abhydrolase_1 PF00561.20 OAG42244.1 - 4e-14 52.9 0.2 1.2e-12 48.1 0.1 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG42244.1 - 1.4e-05 25.8 0.8 2.5e-05 25.0 0.8 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG42244.1 - 0.00084 18.7 0.0 0.058 12.6 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 OAG42244.1 - 0.044 13.2 0.0 0.074 12.5 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 OAG42244.1 - 0.059 13.2 0.0 0.34 10.7 0.0 2.1 1 1 0 1 1 1 0 alpha/beta hydrolase fold Esterase PF00756.20 OAG42244.1 - 0.12 12.0 0.0 0.24 11.0 0.0 1.6 2 0 0 2 2 2 0 Putative esterase Abhydrolase_2 PF02230.16 OAG42244.1 - 0.13 12.1 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase DUF3425 PF11905.8 OAG42245.1 - 6.3e-23 81.1 0.1 1e-22 80.4 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 OAG42245.1 - 0.1 12.7 15.6 2 8.6 10.4 2.3 1 1 1 2 2 2 0 bZIP transcription factor Uso1_p115_C PF04871.13 OAG42245.1 - 0.48 10.8 3.2 0.77 10.1 3.2 1.2 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Aldedh PF00171.22 OAG42246.1 - 4.9e-152 506.6 0.0 6.5e-152 506.2 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 OAG42246.1 - 0.066 12.6 0.0 0.29 10.5 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1487) FAD_binding_2 PF00890.24 OAG42247.1 - 4.8e-05 22.6 0.3 0.0004 19.6 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.19 OAG42247.1 - 0.00014 21.2 0.9 0.3 10.3 0.1 2.1 1 1 1 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 OAG42247.1 - 0.0015 17.8 0.1 0.0023 17.2 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG42247.1 - 0.0024 18.0 0.3 0.053 13.8 0.0 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 OAG42247.1 - 0.0092 15.4 0.7 0.044 13.1 0.1 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.24 OAG42247.1 - 0.013 15.1 0.0 0.029 13.9 0.0 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 OAG42247.1 - 0.047 12.4 0.0 0.068 11.9 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein AlaDh_PNT_C PF01262.21 OAG42247.1 - 0.068 12.4 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 OAG42247.1 - 0.13 11.3 0.1 0.17 11.0 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 OAG42247.1 - 0.14 11.4 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Aldedh PF00171.22 OAG42248.1 - 3.1e-164 546.9 0.6 3.5e-164 546.7 0.6 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Glu_syn_central PF04898.14 OAG42248.1 - 0.05 13.1 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 Glutamate synthase central domain Lactamase_B PF00753.27 OAG42249.1 - 1.2e-09 38.4 0.1 2.3e-09 37.6 0.1 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OAG42249.1 - 0.068 12.7 0.1 0.57 9.7 0.0 2.4 2 1 0 2 2 2 0 Beta-lactamase superfamily domain adh_short PF00106.25 OAG42250.1 - 6.4e-36 123.6 0.0 6e-26 91.1 0.0 2.0 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAG42250.1 - 8.3e-24 84.4 0.1 2.4e-15 56.8 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG42250.1 - 1.7e-11 44.3 0.0 2.7e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 OAG42250.1 - 0.012 14.6 0.0 0.035 13.1 0.0 1.7 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 OAG42250.1 - 0.016 14.3 0.0 0.023 13.8 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 OAG42250.1 - 0.076 12.2 0.0 0.24 10.6 0.0 1.9 1 1 0 1 1 1 0 Male sterility protein RNF220 PF15926.5 OAG42251.1 - 0.095 12.3 0.1 0.19 11.3 0.0 1.4 2 0 0 2 2 2 0 E3 ubiquitin-protein ligase RNF220 DUF3094 PF11293.8 OAG42251.1 - 0.16 11.7 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3094) TRI12 PF06609.13 OAG42252.1 - 2.6e-46 158.2 25.8 3.4e-46 157.9 25.8 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG42252.1 - 3.2e-19 69.1 46.2 1.1e-18 67.3 45.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily NPR3 PF03666.13 OAG42253.1 - 1.3e-139 466.0 0.0 1.3e-139 466.0 0.0 2.2 2 0 0 2 2 2 1 Nitrogen Permease regulator of amino acid transport activity 3 La PF05383.17 OAG42254.1 - 1e-19 70.3 0.2 1.8e-19 69.5 0.2 1.4 1 0 0 1 1 1 1 La domain PUA PF01472.20 OAG42255.1 - 9.2e-14 51.2 0.3 1.4e-13 50.5 0.3 1.3 1 0 0 1 1 1 1 PUA domain Pre-PUA PF17832.1 OAG42255.1 - 3.5e-07 30.8 0.2 5.5e-07 30.2 0.2 1.3 1 0 0 1 1 1 1 Pre-PUA-like domain DUF1947 PF09183.10 OAG42255.1 - 0.012 15.8 0.1 0.026 14.8 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1947) Rieske PF00355.26 OAG42256.1 - 2.9e-16 59.2 0.0 5.7e-16 58.2 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Ring_hydroxyl_A PF00848.19 OAG42256.1 - 0.093 12.7 0.0 1 9.3 0.0 2.1 2 0 0 2 2 2 0 Ring hydroxylating alpha subunit (catalytic domain) Ring_hydroxyl_A PF00848.19 OAG42257.1 - 1.6e-20 74.0 0.0 3e-09 37.1 0.0 2.2 1 1 1 2 2 2 2 Ring hydroxylating alpha subunit (catalytic domain) UPF0029 PF01205.19 OAG42258.1 - 7e-19 68.1 0.0 7e-19 68.1 0.0 2.3 4 0 0 4 4 4 1 Uncharacterized protein family UPF0029 Serglycin PF04360.12 OAG42258.1 - 1.4 8.8 5.2 4.8 7.1 0.0 2.9 3 0 0 3 3 3 0 Serglycin Mucin PF01456.17 OAG42258.1 - 1.6 8.7 36.7 0.034 14.1 9.5 3.2 3 0 0 3 3 3 0 Mucin-like glycoprotein Shisa PF13908.6 OAG42258.1 - 9 6.5 8.1 1.7 8.9 3.0 2.1 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator APS_kinase PF01583.20 OAG42260.1 - 1.1e-68 230.1 0.0 1.4e-68 229.8 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.6 OAG42260.1 - 1.3e-05 25.3 0.0 2.3e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 OAG42260.1 - 0.00048 20.7 0.0 0.00062 20.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 OAG42260.1 - 0.0083 15.9 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain KTI12 PF08433.10 OAG42260.1 - 0.01 15.3 0.0 0.015 14.7 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Zeta_toxin PF06414.12 OAG42260.1 - 0.028 13.7 0.0 0.049 12.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_16 PF13191.6 OAG42260.1 - 0.07 13.5 0.0 0.091 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain CPT PF07931.12 OAG42260.1 - 0.075 12.9 0.0 0.25 11.1 0.0 1.9 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_23 PF13476.6 OAG42260.1 - 0.15 12.5 0.0 0.24 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AFG1_ATPase PF03969.16 OAG42261.1 - 3.1e-54 184.3 0.8 1e-23 83.9 0.0 5.0 4 1 1 5 5 5 4 AFG1-like ATPase AAA_16 PF13191.6 OAG42261.1 - 0.00055 20.4 0.1 0.0044 17.4 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 OAG42261.1 - 0.0055 17.0 0.0 0.012 15.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 OAG42261.1 - 0.14 12.2 0.0 1 9.3 0.0 2.2 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 OAG42261.1 - 0.16 11.3 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI FAD_binding_3 PF01494.19 OAG42264.1 - 3.9e-82 276.3 0.0 5.2e-82 275.9 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 OAG42264.1 - 4.2e-05 22.9 0.0 0.0013 18.0 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAG42264.1 - 9.8e-05 22.1 1.1 0.06 12.9 0.1 3.5 4 0 0 4 4 4 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 OAG42264.1 - 0.00016 22.1 0.0 0.062 13.9 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAG42264.1 - 0.00041 19.5 0.0 0.0085 15.2 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 OAG42264.1 - 0.0033 17.6 0.1 0.0089 16.2 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 OAG42264.1 - 0.0088 15.1 0.2 0.022 13.8 0.2 1.7 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_7 PF13241.6 OAG42264.1 - 0.031 14.7 0.0 0.073 13.5 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Thi4 PF01946.17 OAG42264.1 - 0.046 12.9 0.0 0.085 12.1 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 OAG42264.1 - 0.22 10.7 0.1 0.57 9.4 0.1 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Git3 PF11710.8 OAG42265.1 - 2.4e-22 79.7 14.6 8.9e-22 77.9 14.6 1.8 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.21 OAG42265.1 - 9.6e-10 38.2 6.3 1.4e-09 37.6 6.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) GPR_Gpa2_C PF11970.8 OAG42265.1 - 1.4e-05 25.1 0.5 1.4e-05 25.1 0.5 2.6 2 1 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term Dicty_CAR PF05462.11 OAG42265.1 - 0.00047 19.4 11.0 0.00047 19.4 11.0 1.5 1 1 0 1 1 1 1 Slime mold cyclic AMP receptor Acyl_transf_1 PF00698.21 OAG42266.1 - 5.7e-16 58.9 0.0 5.1e-11 42.6 0.0 2.1 1 1 1 2 2 2 2 Acyl transferase domain zinc_ribbon_6 PF14599.6 OAG42267.1 - 1.3e-26 92.4 1.7 1.3e-26 92.4 1.7 3.9 3 2 1 4 4 4 1 Zinc-ribbon zf-CHY PF05495.12 OAG42267.1 - 9.9e-19 67.6 21.3 9.9e-19 67.6 21.3 3.4 2 1 1 3 3 3 2 CHY zinc finger zf-RING_2 PF13639.6 OAG42267.1 - 9.3e-09 35.5 10.2 9.3e-09 35.5 10.2 5.3 2 2 3 5 5 5 1 Ring finger domain zf-C3HC4_3 PF13920.6 OAG42267.1 - 8.6e-05 22.3 6.8 8.6e-05 22.3 6.8 6.1 3 2 3 6 6 6 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAG42267.1 - 0.00012 21.9 9.7 0.00012 21.9 9.7 6.1 3 2 1 4 4 4 1 zinc-RING finger domain Prok-RING_4 PF14447.6 OAG42267.1 - 0.00067 19.5 5.1 0.00067 19.5 5.1 6.0 4 2 1 5 5 5 2 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 OAG42267.1 - 0.0018 18.0 11.9 0.0018 18.0 11.9 6.3 3 2 4 7 7 7 1 Zinc finger, C3HC4 type (RING finger) EcoRI_methylase PF13651.6 OAG42267.1 - 0.035 13.4 0.0 0.052 12.8 0.0 1.2 1 0 0 1 1 1 0 Adenine-specific methyltransferase EcoRI Zn-C2H2_12 PF18112.1 OAG42267.1 - 2.6 8.6 9.6 5.1 7.7 0.1 3.5 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain Aldo_ket_red PF00248.21 OAG42268.1 - 4.3e-66 223.1 0.0 9.9e-66 221.9 0.0 1.5 2 0 0 2 2 2 1 Aldo/keto reductase family T2SS_PulS_OutS PF09691.10 OAG42268.1 - 0.092 12.9 0.0 0.46 10.7 0.0 2.1 2 0 0 2 2 2 0 Type II secretion system pilotin lipoprotein (PulS_OutS) Glyco_hydro_15 PF00723.21 OAG42269.1 - 5.1e-75 253.0 0.0 6e-75 252.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.19 OAG42269.1 - 2e-12 46.8 0.1 3.9e-12 45.9 0.1 1.5 1 0 0 1 1 1 1 Starch binding domain AMP-binding PF00501.28 OAG42270.1 - 1.4e-25 89.8 0.0 1.9e-25 89.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme DIOX_N PF14226.6 OAG42271.1 - 8e-27 94.3 0.0 1.3e-26 93.7 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OAG42271.1 - 1.1e-16 61.1 0.0 2.7e-16 59.9 0.0 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Rrn6 PF10214.9 OAG42273.1 - 8.7e-115 385.1 5.1 1.1e-114 384.9 5.1 1.0 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor SLAC1 PF03595.17 OAG42275.1 - 1.7e-73 247.7 47.7 2e-73 247.5 47.7 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel PI-PLC-X PF00388.19 OAG42276.1 - 1.6e-09 37.5 0.0 2.5e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain CCDC73 PF15818.5 OAG42276.1 - 0.27 9.1 0.0 0.35 8.6 0.0 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 73 family 2-oxoacid_dh PF00198.23 OAG42277.1 - 2.9e-76 256.0 0.5 4e-76 255.5 0.5 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 OAG42277.1 - 5.2e-19 67.8 0.1 1.1e-18 66.8 0.1 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 OAG42277.1 - 1.4e-14 54.1 0.3 2.8e-14 53.1 0.3 1.5 1 0 0 1 1 1 1 e3 binding domain SspB PF04386.13 OAG42277.1 - 0.00047 20.1 0.7 0.00089 19.2 0.7 1.4 1 0 0 1 1 1 1 Stringent starvation protein B Biotin_lipoyl_2 PF13533.6 OAG42277.1 - 0.091 12.6 0.3 0.42 10.5 0.3 2.1 2 0 0 2 2 2 0 Biotin-lipoyl like DUF1280 PF06918.14 OAG42277.1 - 0.21 11.2 0.1 0.36 10.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1280) CwfJ_C_2 PF04676.14 OAG42278.1 - 5.8e-31 107.3 0.1 5.8e-31 107.3 0.1 2.3 3 0 0 3 3 3 1 Protein similar to CwfJ C-terminus 2 CwfJ_C_1 PF04677.15 OAG42278.1 - 1.6e-28 99.0 0.0 3e-28 98.1 0.0 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 FumaraseC_C PF10415.9 OAG42278.1 - 0.07 13.6 0.5 2.2 8.8 0.1 2.6 2 0 0 2 2 2 0 Fumarase C C-terminus Pkinase PF00069.25 OAG42279.1 - 1.6e-22 80.2 0.0 1.8e-22 79.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG42279.1 - 2.3e-16 59.9 0.0 3.2e-16 59.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 OAG42279.1 - 0.063 12.9 0.0 0.095 12.3 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Aa_trans PF01490.18 OAG42280.1 - 2.1e-21 76.1 33.4 2.9e-21 75.7 33.4 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein ATP_bind_1 PF03029.17 OAG42282.1 - 8e-74 248.4 0.1 2.1e-73 247.0 0.0 1.6 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 OAG42282.1 - 2.8e-06 27.0 0.0 0.00095 18.7 0.0 3.0 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MeaB PF03308.16 OAG42282.1 - 5.2e-06 25.6 0.1 0.0067 15.4 0.0 2.4 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_24 PF13479.6 OAG42282.1 - 0.0016 18.2 0.0 0.0042 16.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 OAG42282.1 - 0.0021 18.1 0.0 0.017 15.2 0.0 2.4 2 1 0 2 2 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 OAG42282.1 - 0.0035 17.8 0.0 0.011 16.1 0.0 1.9 2 1 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 OAG42282.1 - 0.004 17.1 0.0 0.021 14.7 0.0 2.0 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 OAG42282.1 - 0.0043 17.3 0.0 0.017 15.4 0.0 2.1 1 0 0 1 1 1 1 AAA domain CLP1_P PF16575.5 OAG42282.1 - 0.0049 16.7 0.0 0.02 14.7 0.0 2.0 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop PRK PF00485.18 OAG42282.1 - 0.0058 16.4 0.4 0.082 12.6 0.0 2.4 3 0 0 3 3 3 1 Phosphoribulokinase / Uridine kinase family NB-ARC PF00931.22 OAG42282.1 - 0.0077 15.4 0.5 0.021 14.0 0.0 1.8 2 1 0 2 2 2 1 NB-ARC domain SRP54 PF00448.22 OAG42282.1 - 0.0091 15.6 0.0 0.02 14.5 0.0 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain PduV-EutP PF10662.9 OAG42282.1 - 0.011 15.5 0.1 0.081 12.7 0.0 2.4 3 1 1 4 4 3 0 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 OAG42282.1 - 0.011 15.3 0.0 0.12 11.9 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region FeoB_N PF02421.18 OAG42282.1 - 0.011 15.2 0.0 0.33 10.5 0.0 2.6 3 0 0 3 3 3 0 Ferrous iron transport protein B G-alpha PF00503.20 OAG42282.1 - 0.013 14.7 0.4 0.49 9.5 0.0 2.6 3 0 0 3 3 3 0 G-protein alpha subunit Roc PF08477.13 OAG42282.1 - 0.016 15.5 0.0 1.9 8.7 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_30 PF13604.6 OAG42282.1 - 0.016 14.9 0.0 0.027 14.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 OAG42282.1 - 0.023 14.9 1.6 0.035 14.3 0.0 2.1 3 0 0 3 3 2 0 AAA domain ATPase_2 PF01637.18 OAG42282.1 - 0.042 13.8 0.4 0.4 10.6 0.0 2.2 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Thymidylate_kin PF02223.17 OAG42282.1 - 0.065 12.9 1.0 0.57 9.8 0.0 2.3 2 0 0 2 2 2 0 Thymidylate kinase AAA_14 PF13173.6 OAG42282.1 - 0.092 12.8 0.0 0.31 11.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain Arf PF00025.21 OAG42282.1 - 0.12 11.8 0.0 9.4 5.7 0.0 2.9 3 0 0 3 3 3 0 ADP-ribosylation factor family RNA_helicase PF00910.22 OAG42282.1 - 0.14 12.5 1.0 3.7 8.0 0.0 3.0 3 0 0 3 3 3 0 RNA helicase cobW PF02492.19 OAG42282.1 - 0.15 11.6 0.0 2.2 7.8 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.17 OAG42282.1 - 0.19 11.8 0.9 4.2 7.4 0.0 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain DUF1943 PF09172.11 OAG42282.1 - 0.23 10.6 2.8 0.45 9.7 2.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) SAPS PF04499.15 OAG42282.1 - 0.62 8.8 4.3 0.9 8.3 4.3 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein AAA_18 PF13238.6 OAG42282.1 - 1.1 9.8 0.0 1.1 9.8 0.0 2.8 3 1 0 3 3 1 0 AAA domain DUF2151 PF10221.9 OAG42282.1 - 1.9 7.0 5.5 2.7 6.5 5.5 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator Ribosomal_L6 PF00347.23 OAG42283.1 - 8.2e-24 84.1 6.7 3.8e-11 43.5 0.2 2.2 2 0 0 2 2 2 2 Ribosomal protein L6 Ank_2 PF12796.7 OAG42284.1 - 3e-13 50.2 0.0 3.4e-08 34.0 0.0 3.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OAG42284.1 - 2.5e-08 33.5 0.0 0.18 12.5 0.0 4.3 3 0 0 3 3 3 3 Ankyrin repeat NACHT PF05729.12 OAG42284.1 - 3e-08 33.8 0.0 5.5e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 NACHT domain Ank_4 PF13637.6 OAG42284.1 - 2.7e-07 31.0 0.0 0.0032 18.0 0.0 3.3 3 0 0 3 3 2 2 Ankyrin repeats (many copies) Abhydrolase_6 PF12697.7 OAG42284.1 - 4.6e-06 27.4 3.4 1.2e-05 26.1 3.4 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ank_5 PF13857.6 OAG42284.1 - 1.5e-05 25.2 0.0 0.038 14.3 0.0 3.5 1 1 2 3 3 3 2 Ankyrin repeats (many copies) AAA_16 PF13191.6 OAG42284.1 - 1.6e-05 25.3 0.0 5.1e-05 23.7 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain Ank PF00023.30 OAG42284.1 - 0.00019 21.7 0.1 0.71 10.4 0.0 3.4 3 0 0 3 3 2 2 Ankyrin repeat AAA_22 PF13401.6 OAG42284.1 - 0.00039 20.7 0.0 0.0014 18.9 0.0 1.9 2 0 0 2 2 1 1 AAA domain KAP_NTPase PF07693.14 OAG42284.1 - 0.008 15.4 0.7 0.55 9.4 0.2 2.4 1 1 1 2 2 2 1 KAP family P-loop domain ABC_tran PF00005.27 OAG42284.1 - 0.014 15.9 0.0 0.032 14.8 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA PF00004.29 OAG42284.1 - 0.017 15.5 0.0 0.04 14.4 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 OAG42284.1 - 0.024 15.0 0.0 0.059 13.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 OAG42284.1 - 0.042 14.4 0.0 0.12 12.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF676 PF05057.14 OAG42284.1 - 0.054 13.0 0.0 0.2 11.2 0.0 1.9 1 1 0 1 1 1 0 Putative serine esterase (DUF676) Zeta_toxin PF06414.12 OAG42284.1 - 0.091 12.0 0.0 0.24 10.7 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin Viral_helicase1 PF01443.18 OAG42284.1 - 0.14 11.9 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase LCAT PF02450.15 OAG42284.1 - 0.25 10.5 0.0 2.7 7.1 0.0 2.0 2 0 0 2 2 2 0 Lecithin:cholesterol acyltransferase Ras PF00071.22 OAG42285.1 - 8.1e-46 155.6 0.0 9.7e-46 155.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAG42285.1 - 2.4e-21 76.2 0.0 3e-21 75.9 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAG42285.1 - 2.9e-07 30.1 0.0 3.8e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OAG42285.1 - 0.0058 16.0 0.0 0.0094 15.3 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 OAG42285.1 - 0.014 14.6 0.0 0.035 13.3 0.0 1.5 1 1 0 1 1 1 0 G-protein alpha subunit MMR_HSR1 PF01926.23 OAG42285.1 - 0.038 14.1 0.0 0.052 13.6 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase SRPRB PF09439.10 OAG42285.1 - 0.047 13.1 0.0 0.057 12.9 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 OAG42285.1 - 0.052 13.5 0.0 8 6.3 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase Putative_PNPOx PF01243.20 OAG42286.1 - 4.4e-10 39.6 0.0 1.2e-09 38.2 0.0 1.7 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Pyrid_oxidase_2 PF13883.6 OAG42286.1 - 0.0029 17.6 0.1 0.0045 17.0 0.1 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxase_2 PF12766.7 OAG42286.1 - 0.032 14.9 0.0 0.052 14.2 0.0 1.3 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase Pro_racemase PF05544.11 OAG42286.1 - 0.11 11.5 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Proline racemase NIPSNAP PF07978.13 OAG42287.1 - 1.5e-37 127.9 0.1 2.5e-27 95.1 0.0 2.3 2 0 0 2 2 2 2 NIPSNAP Rsm22 PF09243.10 OAG42288.1 - 3.9e-30 105.1 0.1 1.5e-25 90.0 0.1 4.0 2 1 0 2 2 2 1 Mitochondrial small ribosomal subunit Rsm22 CSRNP_N PF16019.5 OAG42288.1 - 0.13 12.1 2.7 0.3 11.0 0.0 2.4 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus SUR7 PF06687.12 OAG42289.1 - 0.46 10.1 4.9 6.6 6.3 0.8 3.0 2 1 1 3 3 3 0 SUR7/PalI family Ycf66_N PF07444.11 OAG42289.1 - 2.5 8.3 8.8 0.48 10.6 0.2 3.7 4 1 0 4 4 4 0 Ycf66 protein N-terminus COesterase PF00135.28 OAG42290.1 - 6.7e-64 216.6 0.0 1.1e-63 215.9 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAG42290.1 - 9.9e-11 41.9 0.1 6.7e-06 26.1 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OAG42290.1 - 0.033 13.7 0.0 0.059 12.8 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Say1_Mug180 PF10340.9 OAG42290.1 - 0.26 10.1 0.1 16 4.2 0.0 2.1 2 0 0 2 2 2 0 Steryl acetyl hydrolase DUF2914 PF11141.8 OAG42290.1 - 0.39 10.5 3.0 30 4.5 0.3 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2914) Abhydrolase_1 PF00561.20 OAG42291.1 - 2.5e-18 66.7 0.0 1.4e-17 64.2 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG42291.1 - 5.8e-14 53.2 8.8 2.4e-13 51.2 8.8 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG42291.1 - 4.4e-08 32.7 0.0 4.8e-07 29.3 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 OAG42291.1 - 0.17 10.8 0.0 0.27 10.1 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme GLE1 PF07817.13 OAG42292.1 - 2e-39 135.3 0.0 3.5e-39 134.5 0.0 1.4 1 0 0 1 1 1 1 GLE1-like protein AF-4 PF05110.13 OAG42292.1 - 3.5 5.6 32.2 4.4 5.3 32.2 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein RNB PF00773.19 OAG42293.1 - 1e-84 284.7 0.0 2.2e-84 283.6 0.0 1.6 1 0 0 1 1 1 1 RNB domain Dis3l2_C_term PF17877.1 OAG42293.1 - 2.1e-26 92.0 0.0 7.5e-26 90.3 0.0 2.0 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal OB_Dis3 PF17849.1 OAG42293.1 - 1.6e-25 88.9 0.0 4e-25 87.7 0.0 1.7 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) CSD2 PF17876.1 OAG42293.1 - 9.2e-05 22.5 0.0 0.041 14.0 0.0 2.7 2 0 0 2 2 2 2 Cold shock domain Rrp44_CSD1 PF17216.3 OAG42293.1 - 0.00045 20.0 0.0 0.00088 19.0 0.0 1.4 1 0 0 1 1 1 1 Rrp44-like cold shock domain Rrp44_S1 PF17215.3 OAG42293.1 - 0.11 12.5 0.0 0.3 11.1 0.0 1.7 1 0 0 1 1 1 0 S1 domain DHO_dh PF01180.21 OAG42294.1 - 8.6e-17 61.3 0.0 1.2e-16 60.8 0.0 1.1 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase EF1_GNE PF00736.19 OAG42295.1 - 3.5e-31 107.2 4.2 7e-31 106.3 4.2 1.5 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 OAG42295.1 - 7.2e-12 45.5 6.0 7.2e-12 45.5 6.0 2.9 3 0 0 3 3 3 1 Eukaryotic elongation factor 1 beta central acidic region GST_C PF00043.25 OAG42295.1 - 0.0089 16.2 0.9 0.035 14.3 0.0 2.4 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OAG42295.1 - 0.075 13.2 0.1 0.2 11.9 0.0 1.7 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain DUF211 PF02680.14 OAG42295.1 - 0.091 12.9 1.6 0.14 12.3 1.6 1.4 1 1 0 1 1 1 0 Uncharacterized ArCR, COG1888 DUF4470 PF14737.6 OAG42296.1 - 8.3e-12 45.1 0.1 3.2e-08 33.6 0.0 2.6 1 1 1 2 2 2 2 Domain of unknown function (DUF4470) BTB PF00651.31 OAG42297.1 - 1.6e-06 28.3 0.0 4e-06 27.0 0.0 1.6 2 0 0 2 2 2 1 BTB/POZ domain AAA_2 PF07724.14 OAG42298.1 - 1.7e-47 161.7 0.1 1.5e-45 155.4 0.0 3.1 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 OAG42298.1 - 6.7e-36 122.4 2.0 6.7e-36 122.4 2.0 2.6 1 1 1 2 2 2 1 AAA lid domain ClpB_D2-small PF10431.9 OAG42298.1 - 5.3e-27 93.7 0.1 2.3e-26 91.7 0.1 2.2 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 OAG42298.1 - 3.6e-21 76.0 0.1 9.2e-11 42.3 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 OAG42298.1 - 4.1e-14 52.8 0.2 1.6e-08 34.6 0.0 3.2 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OAG42298.1 - 4.3e-09 37.0 9.5 0.001 19.5 0.1 4.3 3 2 2 5 5 4 2 AAA ATPase domain Sigma54_activat PF00158.26 OAG42298.1 - 1e-08 35.1 1.0 5.6e-05 22.9 0.1 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_14 PF13173.6 OAG42298.1 - 3.2e-07 30.5 0.0 0.018 15.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 OAG42298.1 - 3.3e-07 30.7 3.5 0.017 15.4 0.1 3.8 3 2 0 3 3 2 2 AAA domain TniB PF05621.11 OAG42298.1 - 4.4e-06 26.2 0.0 0.0098 15.3 0.0 4.2 4 1 0 4 4 3 1 Bacterial TniB protein AAA_7 PF12775.7 OAG42298.1 - 1e-05 25.1 0.0 0.032 13.8 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region IstB_IS21 PF01695.17 OAG42298.1 - 2.7e-05 24.0 0.7 0.083 12.6 0.1 2.9 3 0 0 3 3 2 2 IstB-like ATP binding protein NACHT PF05729.12 OAG42298.1 - 3.2e-05 23.9 0.0 0.12 12.3 0.0 2.6 2 0 0 2 2 2 2 NACHT domain ATPase_2 PF01637.18 OAG42298.1 - 4.7e-05 23.4 8.2 0.5 10.2 0.0 4.4 3 2 1 4 4 3 2 ATPase domain predominantly from Archaea AAA_28 PF13521.6 OAG42298.1 - 9.6e-05 22.7 2.0 0.048 13.9 0.0 3.7 3 1 0 3 3 3 1 AAA domain AAA_18 PF13238.6 OAG42298.1 - 0.00011 22.8 1.0 0.43 11.1 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_24 PF13479.6 OAG42298.1 - 0.00035 20.4 0.0 0.35 10.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 OAG42298.1 - 0.00071 20.1 0.9 0.77 10.3 0.0 3.4 3 0 0 3 3 3 1 ABC transporter Mg_chelatase PF01078.21 OAG42298.1 - 0.00079 18.9 0.3 3.5 7.0 0.0 3.8 3 1 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 OAG42298.1 - 0.0012 19.2 0.2 0.17 12.2 0.0 3.3 2 1 0 2 2 2 1 AAA domain Roc PF08477.13 OAG42298.1 - 0.0014 18.8 0.1 0.49 10.6 0.0 2.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase RNA_helicase PF00910.22 OAG42298.1 - 0.0016 18.8 0.0 0.78 10.2 0.0 2.7 2 1 0 2 2 2 1 RNA helicase ResIII PF04851.15 OAG42298.1 - 0.0025 17.8 0.5 3 7.8 0.0 3.4 4 0 0 4 4 3 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 OAG42298.1 - 0.003 17.3 1.8 0.16 11.7 0.0 3.3 3 0 0 3 3 2 1 AAA domain TsaE PF02367.17 OAG42298.1 - 0.0033 17.4 0.1 2.3 8.2 0.0 2.6 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RsgA_GTPase PF03193.16 OAG42298.1 - 0.0034 17.3 0.1 1.1 9.1 0.0 2.8 2 0 0 2 2 2 1 RsgA GTPase SRP54 PF00448.22 OAG42298.1 - 0.0069 16.0 0.0 0.96 9.0 0.0 2.5 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain PduV-EutP PF10662.9 OAG42298.1 - 0.012 15.4 0.0 0.62 9.8 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF815 PF05673.13 OAG42298.1 - 0.012 14.8 0.3 0.92 8.6 0.1 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF815) AAA_33 PF13671.6 OAG42298.1 - 0.016 15.3 1.2 4.3 7.5 0.0 2.9 3 0 0 3 3 2 0 AAA domain Zeta_toxin PF06414.12 OAG42298.1 - 0.018 14.3 0.0 1.9 7.7 0.0 2.7 2 0 0 2 2 2 0 Zeta toxin AAA_25 PF13481.6 OAG42298.1 - 0.023 14.3 0.2 6.3 6.3 0.1 3.4 2 1 1 3 3 3 0 AAA domain RuvB_N PF05496.12 OAG42298.1 - 0.023 14.4 0.2 2.2 8.0 0.0 3.3 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain AAA_6 PF12774.7 OAG42298.1 - 0.03 13.3 0.1 3.7 6.4 0.0 2.9 3 0 0 3 3 3 0 Hydrolytic ATP binding site of dynein motor region TrwB_AAD_bind PF10412.9 OAG42298.1 - 0.037 12.9 0.0 0.73 8.7 0.1 2.4 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain NTPase_1 PF03266.15 OAG42298.1 - 0.042 13.8 0.1 0.68 9.8 0.0 2.7 2 0 0 2 2 2 0 NTPase AAA_29 PF13555.6 OAG42298.1 - 0.053 13.3 0.0 7.2 6.4 0.0 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain ATP_bind_1 PF03029.17 OAG42298.1 - 0.074 12.8 0.0 1.3 8.8 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Torsin PF06309.11 OAG42298.1 - 0.15 12.2 0.0 1.7 8.7 0.0 2.5 3 0 0 3 3 2 0 Torsin DUF99 PF01949.16 OAG42298.1 - 0.15 11.4 2.2 1.3 8.4 0.0 2.7 3 0 0 3 3 2 0 Protein of unknown function DUF99 UvrD-helicase PF00580.21 OAG42298.1 - 0.16 11.5 3.1 0.58 9.6 0.1 2.3 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain AAA_21 PF13304.6 OAG42298.1 - 0.24 11.2 3.0 0.7 9.6 0.0 3.0 3 1 1 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system Rootletin PF15035.6 OAG42298.1 - 0.4 10.7 11.4 0.21 11.6 8.8 1.7 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion GrpE PF01025.19 OAG42298.1 - 0.47 10.1 12.3 0.24 11.0 9.6 1.9 2 0 0 2 2 1 0 GrpE NB-ARC PF00931.22 OAG42298.1 - 0.51 9.5 3.8 7.3 5.7 0.0 3.2 3 0 0 3 3 3 0 NB-ARC domain GAS PF13851.6 OAG42298.1 - 1 8.7 13.0 2.1 7.6 13.0 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DivIC PF04977.15 OAG42298.1 - 2.8 7.8 17.0 2 8.2 9.9 2.8 1 1 1 2 2 2 0 Septum formation initiator DUF4446 PF14584.6 OAG42298.1 - 2.8 7.9 5.0 1.5 8.8 2.3 1.8 2 0 0 2 2 1 0 Protein of unknown function (DUF4446) CENP-H PF05837.12 OAG42298.1 - 5.3 7.5 11.6 15 6.0 11.6 1.7 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DUF4094 PF13334.6 OAG42298.1 - 5.6 7.5 7.3 0.51 10.8 0.6 2.7 3 0 0 3 3 1 0 Domain of unknown function (DUF4094) Atg14 PF10186.9 OAG42298.1 - 8.3 5.4 8.4 13 4.8 8.4 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 UPF0242 PF06785.11 OAG42298.1 - 9.1 6.3 16.4 5.5 7.0 12.4 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Sugar_tr PF00083.24 OAG42299.1 - 2.5e-92 310.1 24.8 3.2e-92 309.8 24.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG42299.1 - 2.1e-17 63.1 27.3 2.1e-17 63.1 27.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Methyltransf_33 PF10017.9 OAG42300.1 - 1.3e-70 238.0 0.0 1.5e-70 237.8 0.0 1.0 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent NUC205 PF08168.11 OAG42300.1 - 0.05 13.1 0.1 3.2 7.3 0.0 2.4 2 0 0 2 2 2 0 NUC205 domain Methyltransf_2 PF00891.18 OAG42301.1 - 1.7e-20 73.2 0.0 3e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 OAG42301.1 - 0.0086 16.8 0.0 0.029 15.1 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 OAG42301.1 - 0.038 13.7 0.0 0.069 12.9 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase MTS PF05175.14 OAG42301.1 - 0.041 13.4 0.1 0.85 9.1 0.0 2.6 3 0 0 3 3 3 0 Methyltransferase small domain Ank_4 PF13637.6 OAG42302.1 - 0.0018 18.8 0.0 0.074 13.7 0.0 3.0 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG42302.1 - 0.0098 16.3 0.3 6.9 7.6 0.0 4.0 4 0 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.6 OAG42302.1 - 0.16 12.3 0.2 15 6.0 0.0 2.7 2 0 0 2 2 2 0 Ankyrin repeats (many copies) AAA_16 PF13191.6 OAG42303.1 - 2.4e-07 31.3 0.3 3.8e-06 27.4 0.0 2.9 2 2 0 2 2 2 1 AAA ATPase domain SesA PF17107.5 OAG42303.1 - 2.6e-05 24.4 4.5 0.00026 21.2 1.2 3.2 3 1 1 4 4 4 1 N-terminal domain on NACHT_NTPase and P-loop NTPases NACHT PF05729.12 OAG42303.1 - 4.9e-05 23.3 2.2 0.0011 19.0 0.0 3.6 3 2 0 3 3 3 1 NACHT domain AAA_22 PF13401.6 OAG42303.1 - 0.002 18.4 0.7 0.04 14.2 0.0 2.9 2 2 0 2 2 2 1 AAA domain AAA_18 PF13238.6 OAG42303.1 - 0.0096 16.5 0.1 0.034 14.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 OAG42303.1 - 0.013 16.0 0.7 0.15 12.5 0.0 2.6 2 1 0 2 2 2 0 ABC transporter AAA_30 PF13604.6 OAG42303.1 - 0.014 15.1 0.0 0.11 12.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 OAG42303.1 - 0.023 15.1 0.0 0.051 14.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_29 PF13555.6 OAG42303.1 - 0.025 14.3 0.0 0.054 13.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain NB-ARC PF00931.22 OAG42303.1 - 0.049 12.8 0.0 0.22 10.6 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain Ploopntkinase3 PF18751.1 OAG42303.1 - 0.07 13.0 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 cobW PF02492.19 OAG42303.1 - 0.078 12.6 0.0 0.29 10.7 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.29 OAG42303.1 - 0.086 13.3 0.0 1.4 9.4 0.0 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF3686 PF12458.8 OAG42303.1 - 0.14 10.7 0.1 0.23 9.9 0.1 1.2 1 0 0 1 1 1 0 ATPase involved in DNA repair MMR_HSR1 PF01926.23 OAG42303.1 - 0.15 12.2 0.1 1 9.4 0.0 2.5 3 0 0 3 3 3 0 50S ribosome-binding GTPase Helo_like_N PF17111.5 OAG42303.1 - 0.29 10.5 5.7 5.9 6.2 5.4 2.2 1 1 0 1 1 1 0 Fungal N-terminal domain of STAND proteins 2-Hacid_dh_C PF02826.19 OAG42304.1 - 2.1e-50 170.5 0.0 3.1e-50 170.0 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 OAG42304.1 - 4.4e-16 58.8 0.0 6.5e-16 58.2 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 OAG42304.1 - 2.5e-06 27.8 0.0 2.1e-05 24.8 0.0 2.1 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase PROCN PF08083.11 OAG42304.1 - 0.11 11.1 0.0 0.16 10.7 0.0 1.1 1 0 0 1 1 1 0 PROCN (NUC071) domain Fungal_trans PF04082.18 OAG42305.1 - 2.5e-19 69.4 0.0 3.8e-19 68.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain NUDIX PF00293.28 OAG42306.1 - 1.3e-14 54.3 0.1 2.7e-14 53.3 0.1 1.4 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.11 OAG42306.1 - 4.4e-08 33.7 0.0 1.4e-07 32.1 0.0 1.9 2 0 0 2 2 2 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.11 OAG42306.1 - 4.6e-06 26.2 1.2 8.2e-06 25.4 1.2 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain DAO PF01266.24 OAG42307.1 - 8.7e-42 143.9 0.3 1.2e-41 143.5 0.3 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Rieske PF00355.26 OAG42307.1 - 7.2e-09 35.5 0.7 4.8e-08 32.8 0.0 2.4 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain NAD_binding_8 PF13450.6 OAG42307.1 - 1.1e-05 25.5 0.2 3.2e-05 24.1 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 OAG42307.1 - 1.9e-05 24.1 0.2 3.3e-05 23.3 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 OAG42307.1 - 0.00029 20.3 0.7 0.012 15.0 0.3 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG42307.1 - 0.00055 19.3 0.0 0.0011 18.3 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAG42307.1 - 0.00083 18.7 0.3 0.0017 17.7 0.0 1.6 2 0 0 2 2 2 1 Thi4 family Amino_oxidase PF01593.24 OAG42307.1 - 0.008 15.5 0.2 0.019 14.3 0.0 1.6 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 OAG42307.1 - 0.012 14.7 0.3 0.02 14.0 0.3 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 OAG42307.1 - 0.051 12.8 0.0 0.1 11.8 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAG42307.1 - 0.1 13.2 0.1 0.23 12.0 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAG42307.1 - 0.12 11.1 0.1 0.17 10.5 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_9 PF13454.6 OAG42307.1 - 0.17 11.8 0.2 0.42 10.6 0.2 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding Zn_clus PF00172.18 OAG42308.1 - 1.1e-08 35.0 7.4 2.2e-08 34.1 7.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain G-alpha PF00503.20 OAG42309.1 - 2.3e-94 316.5 0.0 2.9e-94 316.2 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 OAG42309.1 - 7.4e-12 45.1 0.6 5.9e-05 22.6 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OAG42309.1 - 0.029 14.4 0.0 2.2 8.4 0.0 2.3 2 0 0 2 2 2 0 50S ribosome-binding GTPase Roc PF08477.13 OAG42309.1 - 0.089 13.0 2.0 6.5 7.0 0.5 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase FtsK_SpoIIIE PF01580.18 OAG42309.1 - 0.11 11.8 0.0 0.23 10.8 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_29 PF13555.6 OAG42309.1 - 0.12 12.1 0.3 0.63 9.8 0.2 2.0 1 1 1 2 2 2 0 P-loop containing region of AAA domain Gtr1_RagA PF04670.12 OAG42309.1 - 0.42 9.9 2.4 3.5 6.9 0.0 2.2 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region DUF3425 PF11905.8 OAG42310.1 - 7.7e-12 45.3 0.1 1.3e-11 44.5 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) zf-C4H2 PF10146.9 OAG42310.1 - 0.031 14.6 0.0 0.043 14.1 0.0 1.2 1 0 0 1 1 1 0 Zinc finger-containing protein bZIP_1 PF00170.21 OAG42310.1 - 0.032 14.3 15.1 0.27 11.4 15.1 2.0 1 1 0 1 1 1 0 bZIP transcription factor PikAIV_N PF18605.1 OAG42310.1 - 0.038 13.6 5.4 0.044 13.4 3.5 2.0 1 1 1 2 2 2 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain DUF463 PF04317.12 OAG42310.1 - 0.049 12.6 0.2 0.078 11.9 0.2 1.2 1 0 0 1 1 1 0 YcjX-like family, DUF463 Seadorna_VP6 PF07407.11 OAG42310.1 - 0.09 11.7 0.5 0.13 11.2 0.5 1.1 1 0 0 1 1 1 0 Seadornavirus VP6 protein bZIP_Maf PF03131.17 OAG42310.1 - 0.33 11.5 9.3 0.65 10.6 9.3 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor IPP-2 PF04979.14 OAG42310.1 - 0.46 11.2 3.2 0.71 10.6 3.2 1.3 1 0 0 1 1 1 0 Protein phosphatase inhibitor 2 (IPP-2) PRKG1_interact PF15898.5 OAG42310.1 - 0.47 11.4 8.3 0.78 10.7 8.3 1.3 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain EMC3_TMCO1 PF01956.16 OAG42310.1 - 1.3 8.7 2.8 2 8.1 2.8 1.2 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like LAMTOR PF15454.6 OAG42310.1 - 1.8 9.2 9.1 1.3 9.7 1.1 2.8 1 1 2 3 3 3 0 Late endosomal/lysosomal adaptor and MAPK and MTOR activator DUF2937 PF11157.8 OAG42310.1 - 3.1 7.5 5.0 4.8 6.9 5.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) Tctex-1 PF03645.13 OAG42311.1 - 2.1e-22 79.3 0.0 2.4e-22 79.1 0.0 1.1 1 0 0 1 1 1 1 Tctex-1 family DUF202 PF02656.15 OAG42313.1 - 1.3e-13 51.1 4.5 1.3e-13 51.1 4.5 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF5134 PF17197.4 OAG42313.1 - 0.012 15.5 0.3 0.015 15.2 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5134) DUF5337 PF17272.2 OAG42313.1 - 1.9 8.4 11.4 0.1 12.5 5.2 2.1 2 1 0 2 2 2 0 Family of unknown function (DUF5337) WD40 PF00400.32 OAG42314.1 - 2.2e-11 44.1 9.0 5.2e-05 23.9 0.0 4.0 4 0 0 4 4 4 2 WD domain, G-beta repeat Nup160 PF11715.8 OAG42314.1 - 3.3e-06 26.0 0.0 0.0019 16.9 0.0 2.3 3 0 0 3 3 3 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 OAG42314.1 - 0.00015 20.9 0.0 0.77 8.7 0.0 3.0 2 1 1 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 OAG42314.1 - 0.0053 17.0 0.1 2 8.7 0.1 3.1 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain PRKG1_interact PF15898.5 OAG42315.1 - 0.021 15.7 2.4 0.022 15.7 0.5 2.1 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain Tup_N PF08581.10 OAG42315.1 - 0.023 15.0 3.8 0.17 12.2 0.5 2.7 2 0 0 2 2 2 0 Tup N-terminal Rootletin PF15035.6 OAG42315.1 - 0.029 14.4 0.5 0.06 13.4 0.5 1.5 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Spc7 PF08317.11 OAG42315.1 - 0.041 12.8 0.1 0.08 11.8 0.1 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF2046 PF09755.9 OAG42315.1 - 0.058 12.6 0.3 0.11 11.7 0.3 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein H4 (DUF2046) CLZ PF16526.5 OAG42315.1 - 0.25 11.7 3.7 0.19 12.1 1.4 1.9 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ZapB PF06005.12 OAG42315.1 - 1.8 9.0 6.6 3.6 8.1 0.2 2.8 2 1 1 3 3 3 0 Cell division protein ZapB Swi5 PF07061.11 OAG42315.1 - 4.6 7.4 6.7 0.62 10.2 2.3 1.8 2 0 0 2 2 2 0 Swi5 SANT_DAMP1_like PF16282.5 OAG42316.1 - 2.4e-29 101.3 0.1 4.5e-29 100.5 0.1 1.5 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 DMAP1 PF05499.12 OAG42316.1 - 2.5e-05 24.2 0.3 2.5e-05 24.2 0.3 2.7 3 0 0 3 3 3 1 DNA methyltransferase 1-associated protein 1 (DMAP1) EMP24_GP25L PF01105.24 OAG42317.1 - 1.2e-48 165.4 0.0 1.4e-48 165.2 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Ima1_N PF09779.9 OAG42318.1 - 3.4e-34 118.6 5.9 6.5e-34 117.7 5.9 1.5 1 0 0 1 1 1 1 Ima1 N-terminal domain DUF3382 PF11862.8 OAG42318.1 - 0.061 13.6 1.1 13 6.2 0.0 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3382) PriA_CRR PF18319.1 OAG42318.1 - 4.7 7.3 8.4 0.24 11.4 1.6 2.3 2 0 0 2 2 2 0 PriA DNA helicase Cys-rich region (CRR) domain Alg14 PF08660.11 OAG42319.1 - 1.3e-51 175.0 0.0 1.9e-51 174.5 0.0 1.3 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like Pkinase PF00069.25 OAG42321.1 - 2.2e-50 171.5 0.0 2.5e-33 115.6 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAG42321.1 - 3.4e-21 75.7 0.0 1e-19 70.9 0.0 2.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAG42321.1 - 7.6e-08 32.0 0.0 9.2e-05 21.9 0.0 2.3 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 OAG42321.1 - 0.0026 17.7 0.0 0.011 15.7 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OAG42321.1 - 0.02 13.7 1.7 0.045 12.5 0.0 2.4 3 0 0 3 3 3 0 Fungal protein kinase Fungal_trans_2 PF11951.8 OAG42322.1 - 0.00012 21.0 0.2 0.00029 19.8 0.2 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain BPL_LplA_LipB PF03099.19 OAG42323.1 - 1.2e-08 34.9 0.0 2.7e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Fungal_trans PF04082.18 OAG42324.1 - 2.1e-21 76.1 0.1 4.2e-21 75.2 0.1 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG42324.1 - 7.8e-09 35.5 10.0 1.4e-08 34.7 10.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAG42325.1 - 1.2e-12 47.4 0.2 2e-12 46.7 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG42325.1 - 4.5e-08 33.1 9.6 8.2e-08 32.2 9.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PQ-loop PF04193.14 OAG42326.1 - 3.2e-37 126.1 11.1 1.4e-18 66.4 2.9 2.8 3 0 0 3 3 3 2 PQ loop repeat ER_lumen_recept PF00810.18 OAG42326.1 - 0.047 14.5 0.2 1 10.2 0.0 2.2 2 0 0 2 2 2 0 ER lumen protein retaining receptor BCD PF15461.6 OAG42326.1 - 1.1 8.6 5.5 3 7.2 3.8 2.4 2 1 0 2 2 2 0 Beta-carotene 15,15'-dioxygenase SPX PF03105.19 OAG42327.1 - 0.047 13.6 10.1 0.048 13.6 10.1 1.2 1 0 0 1 1 1 0 SPX domain Apt1 PF10351.9 OAG42327.1 - 0.069 12.0 6.4 0.07 12.0 6.4 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SOG2 PF10428.9 OAG42327.1 - 8.3 5.5 24.1 11 5.1 24.1 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein MscS_TM PF12794.7 OAG42328.1 - 0.16 10.8 3.5 0.22 10.4 3.5 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Pex19 PF04614.12 OAG42329.1 - 1.1e-62 212.1 10.1 1.1e-62 212.1 10.1 2.2 2 0 0 2 2 2 1 Pex19 protein family Neuromodulin_N PF10580.9 OAG42329.1 - 0.061 13.1 0.1 0.15 11.9 0.1 1.7 1 0 0 1 1 1 0 Gap junction protein N-terminal region Beta-lactamase PF00144.24 OAG42330.1 - 1.6e-28 100.0 1.0 8.5e-28 97.5 1.0 2.0 1 1 0 1 1 1 1 Beta-lactamase Zn_clus PF00172.18 OAG42331.1 - 1.4e-06 28.3 12.1 2.5e-06 27.5 12.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Formyl_trans_N PF00551.19 OAG42332.1 - 2.2e-21 76.4 0.0 3.5e-21 75.8 0.0 1.4 1 0 0 1 1 1 1 Formyl transferase adh_short PF00106.25 OAG42333.1 - 3.1e-34 118.2 0.0 3.7e-34 117.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG42333.1 - 5.9e-33 114.4 0.0 7e-33 114.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG42333.1 - 4.6e-07 29.9 0.1 6.2e-07 29.5 0.1 1.1 1 0 0 1 1 1 1 KR domain Pkinase PF00069.25 OAG42335.1 - 1.7e-27 96.4 0.0 2.3e-27 96.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG42335.1 - 2.6e-14 53.1 0.0 3.6e-14 52.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAG42335.1 - 9.9e-07 27.9 0.0 1.5e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase zf-C2H2 PF00096.26 OAG42336.1 - 2.4e-12 46.6 14.1 2.3e-06 27.7 2.3 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OAG42336.1 - 2.7e-12 46.5 9.3 1.8e-07 31.3 0.2 3.6 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 OAG42336.1 - 3.6e-08 33.6 11.8 0.00073 20.2 1.4 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 OAG42336.1 - 3.8e-08 33.1 5.2 0.00046 20.1 0.3 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OAG42336.1 - 9.3e-06 25.8 0.6 0.33 11.3 0.2 3.7 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OAG42336.1 - 2.3e-05 24.6 1.0 0.012 15.9 0.3 3.5 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 OAG42336.1 - 0.021 14.6 5.4 1.1 9.1 0.5 3.4 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-Di19 PF05605.12 OAG42336.1 - 0.094 13.0 1.4 0.18 12.1 1.4 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2HE PF16278.5 OAG42336.1 - 0.25 11.8 2.1 7.9 7.0 0.3 2.6 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger LIM PF00412.22 OAG42336.1 - 0.66 10.2 3.1 23 5.3 0.1 2.4 1 1 1 2 2 2 0 LIM domain zf-BED PF02892.15 OAG42336.1 - 0.87 9.7 3.2 26 4.9 3.2 2.4 1 1 0 1 1 1 0 BED zinc finger FYVE PF01363.21 OAG42336.1 - 2.3 8.4 4.8 4.2 7.6 4.8 1.5 1 0 0 1 1 1 0 FYVE zinc finger C5HCH PF17982.1 OAG42336.1 - 2.6 8.3 6.7 9.6 6.5 1.1 2.5 1 1 1 2 2 2 0 NSD Cys-His rich domain BEN PF10523.9 OAG42337.1 - 0.054 13.7 0.0 0.13 12.5 0.0 1.7 1 0 0 1 1 1 0 BEN domain THRAP3_BCLAF1 PF15440.6 OAG42337.1 - 0.38 9.7 12.4 0.79 8.7 12.4 1.4 1 0 0 1 1 1 0 THRAP3/BCLAF1 family RTA1 PF04479.13 OAG42338.1 - 3.5e-71 239.1 5.8 3.5e-71 239.1 5.8 2.0 2 0 0 2 2 2 1 RTA1 like protein Orf78 PF06024.12 OAG42338.1 - 0.0018 18.6 0.0 0.85 9.9 0.4 2.6 2 0 0 2 2 2 2 Orf78 (ac78) SUR7 PF06687.12 OAG42338.1 - 0.26 10.9 0.1 0.26 10.9 0.1 3.3 2 1 0 3 3 3 0 SUR7/PalI family Acyl_transf_3 PF01757.22 OAG42339.1 - 4.8e-27 94.9 28.7 6.7e-27 94.4 28.7 1.2 1 0 0 1 1 1 1 Acyltransferase family Fe-ADH PF00465.19 OAG42340.1 - 4e-63 213.4 0.0 5.4e-63 213.0 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 OAG42340.1 - 8.5e-11 42.0 0.1 2e-05 24.5 0.2 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Ribosomal_60s PF00428.19 OAG42341.1 - 1.7e-27 95.8 11.8 2.2e-27 95.4 11.8 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein Cytomega_UL84 PF06284.11 OAG42341.1 - 0.014 13.9 2.9 0.019 13.5 2.9 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein Phage_holin_6_1 PF09682.10 OAG42341.1 - 0.3 11.5 2.0 0.34 11.3 0.1 1.8 2 0 0 2 2 2 0 Bacteriophage holin of superfamily 6 (Holin_LLH) DUF3824 PF12868.7 OAG42341.1 - 1.8 9.2 5.8 2.6 8.7 5.8 1.2 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) Pkinase PF00069.25 OAG42342.1 - 2.7e-15 56.4 0.0 5.5e-14 52.2 0.0 2.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG42342.1 - 0.00019 20.8 0.0 0.006 15.9 0.0 2.5 2 1 0 2 2 2 1 Protein tyrosine kinase CorA PF01544.18 OAG42343.1 - 0.29 10.4 8.5 1.7 7.9 8.5 2.1 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein AA_permease_2 PF13520.6 OAG42344.1 - 1.2e-39 136.3 17.1 2.2e-39 135.5 17.1 1.4 1 0 0 1 1 1 1 Amino acid permease DUF2809 PF10990.8 OAG42344.1 - 5.5 7.7 9.1 0.82 10.4 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2809) CTP_transf_like PF01467.26 OAG42345.1 - 0.0011 19.1 0.0 0.14 12.4 0.0 2.4 2 0 0 2 2 2 2 Cytidylyltransferase-like HIGH_NTase1_ass PF16581.5 OAG42345.1 - 0.16 12.0 0.0 0.25 11.3 0.0 1.2 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region SAP PF02037.27 OAG42347.1 - 1.9e-09 37.0 0.0 4.4e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 SAP domain Asp PF00026.23 OAG42348.1 - 8.7e-72 242.2 6.7 1.3e-71 241.6 6.7 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OAG42348.1 - 1.5e-09 38.4 1.2 1.5e-09 38.4 1.2 3.3 3 1 0 3 3 3 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 OAG42348.1 - 0.00018 22.1 0.1 0.14 12.8 0.0 3.0 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 OAG42348.1 - 0.0026 18.3 0.1 2.3 8.8 0.0 2.8 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease adh_short_C2 PF13561.6 OAG42349.1 - 1.5e-49 168.7 3.9 1.7e-49 168.5 3.9 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG42349.1 - 2.6e-47 160.8 3.7 3.1e-47 160.6 3.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG42349.1 - 3.5e-08 33.6 1.8 3e-07 30.5 1.8 2.0 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 OAG42349.1 - 4.7e-05 22.5 0.5 6.6e-05 22.0 0.5 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 OAG42349.1 - 0.00086 18.8 0.3 0.0019 17.7 0.3 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 OAG42349.1 - 0.041 13.8 0.2 0.064 13.1 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.17 OAG42349.1 - 0.064 12.4 0.3 0.1 11.6 0.3 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Aa_trans PF01490.18 OAG42350.1 - 6.3e-65 219.5 30.2 6.4e-33 114.1 13.5 2.0 1 1 1 2 2 2 2 Transmembrane amino acid transporter protein Serglycin PF04360.12 OAG42351.1 - 0.0045 16.9 4.2 0.0045 16.9 4.2 2.9 3 1 1 4 4 4 1 Serglycin CAML PF14963.6 OAG42352.1 - 0.34 11.0 7.3 0.12 12.5 3.9 1.8 1 1 1 2 2 2 0 Calcium signal-modulating cyclophilin ligand DUF4653 PF15546.6 OAG42352.1 - 0.72 9.4 7.8 0.9 9.1 7.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4653) Apt1 PF10351.9 OAG42352.1 - 2.4 6.9 4.4 2.5 6.9 4.4 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SPX PF03105.19 OAG42352.1 - 9.3 6.0 10.2 11 5.8 10.2 1.2 1 0 0 1 1 1 0 SPX domain Tcf25 PF04910.14 OAG42353.1 - 1.2e-78 264.7 0.2 1.8e-78 264.1 0.2 1.2 1 0 0 1 1 1 1 Transcriptional repressor TCF25 TPR_4 PF07721.14 OAG42353.1 - 0.038 14.6 0.0 0.29 11.9 0.0 2.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.17 OAG42353.1 - 0.12 12.5 2.0 17 5.9 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat YqfQ PF14181.6 OAG42353.1 - 1.1 9.5 14.6 1.7 8.8 11.2 2.6 2 0 0 2 2 2 0 YqfQ-like protein Nop53 PF07767.11 OAG42353.1 - 2.5 7.4 30.5 0.083 12.3 24.1 1.7 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) Herpes_DNAp_acc PF04929.12 OAG42353.1 - 6.4 5.6 14.2 11 4.8 14.2 1.3 1 0 0 1 1 1 0 Herpes DNA replication accessory factor PP2C PF00481.21 OAG42354.1 - 2.7e-42 145.2 0.0 5e-42 144.3 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 OAG42354.1 - 0.00098 18.8 0.0 0.0019 17.9 0.0 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 OAG42354.1 - 0.024 14.6 0.0 2.8 7.8 0.0 2.5 3 0 0 3 3 3 0 Stage II sporulation protein E (SpoIIE) 60KD_IMP PF02096.20 OAG42355.1 - 0.0038 17.2 0.0 0.0046 16.9 0.0 1.1 1 0 0 1 1 1 1 60Kd inner membrane protein CcmH PF03918.14 OAG42355.1 - 0.079 12.3 0.2 0.2 10.9 0.0 1.7 2 0 0 2 2 2 0 Cytochrome C biogenesis protein ALG11_N PF15924.5 OAG42356.1 - 5.4e-81 271.6 0.0 9.9e-81 270.8 0.0 1.4 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 OAG42356.1 - 1.9e-20 73.1 0.0 4.4e-20 71.9 0.0 1.5 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 OAG42356.1 - 4.1e-06 27.3 0.0 8.5e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 OAG42356.1 - 0.0022 18.0 0.0 0.0053 16.8 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase Family 4 FHIPEP PF00771.20 OAG42356.1 - 0.21 10.0 0.0 0.29 9.6 0.0 1.1 1 0 0 1 1 1 0 FHIPEP family UQ_con PF00179.26 OAG42357.1 - 6.1e-50 168.5 0.0 6.8e-50 168.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OAG42357.1 - 7.2e-05 22.5 0.0 0.00013 21.7 0.0 1.4 1 1 0 1 1 1 1 Prokaryotic E2 family B Asn_synthase PF00733.21 OAG42358.1 - 1.4e-91 307.8 0.0 3.6e-88 296.6 0.0 2.1 1 1 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.6 OAG42358.1 - 7e-38 129.3 0.0 1.4e-37 128.3 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 OAG42358.1 - 1.4e-28 99.7 0.0 3.2e-28 98.6 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 OAG42358.1 - 4e-07 29.7 0.0 1e-06 28.4 0.0 1.6 2 0 0 2 2 2 1 Aluminium induced protein NAD_synthase PF02540.17 OAG42358.1 - 0.0084 15.3 0.0 0.022 13.9 0.0 1.6 2 0 0 2 2 2 1 NAD synthase Porin_3 PF01459.22 OAG42359.1 - 2.3e-68 230.6 10.3 3.9e-68 229.8 10.3 1.3 1 1 0 1 1 1 1 Eukaryotic porin DnaJ PF00226.31 OAG42360.1 - 4.1e-20 71.7 1.1 4.1e-20 71.7 1.1 1.9 2 0 0 2 2 2 1 DnaJ domain Adeno_E3 PF06040.11 OAG42360.1 - 0.17 12.1 0.0 20 5.4 0.0 2.5 2 0 0 2 2 2 0 Adenovirus E3 protein Peptidase_M24 PF00557.24 OAG42361.1 - 2.2e-41 141.9 0.0 2.8e-41 141.5 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 YL1 PF05764.13 OAG42361.1 - 0.11 12.6 6.5 0.16 12.1 6.5 1.2 1 0 0 1 1 1 0 YL1 nuclear protein CCDC106 PF15794.5 OAG42361.1 - 1.5 8.5 5.5 2.8 7.6 5.5 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 PGA2 PF07543.12 OAG42361.1 - 2.5 8.1 11.5 0.14 12.2 5.4 1.9 2 0 0 2 2 2 0 Protein trafficking PGA2 CDC45 PF02724.14 OAG42361.1 - 5.8 5.1 7.4 8 4.6 7.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Chorismate_synt PF01264.21 OAG42362.1 - 2.3e-139 463.7 0.0 2.7e-139 463.5 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase Hormone_4 PF00220.17 OAG42362.1 - 0.44 10.6 2.1 1.1 9.4 2.1 1.7 1 0 0 1 1 1 0 Neurohypophysial hormones, N-terminal Domain Kelch_5 PF13854.6 OAG42363.1 - 0.00023 21.1 0.1 3.4 7.8 0.0 3.8 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.6 OAG42363.1 - 0.00069 19.6 1.4 13 5.9 0.0 4.6 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_6 PF13964.6 OAG42363.1 - 0.0013 19.0 0.2 6.7 7.2 0.0 3.9 4 0 0 4 4 4 2 Kelch motif Vpu PF00558.19 OAG42363.1 - 0.11 12.3 0.6 0.43 10.4 0.0 2.1 2 0 0 2 2 2 0 Vpu protein Ribonuc_red_lgC PF02867.15 OAG42364.1 - 4.4e-190 632.7 0.0 6.2e-190 632.2 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 OAG42364.1 - 2.8e-24 84.9 0.0 6.5e-24 83.7 0.0 1.7 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 OAG42364.1 - 7.2e-18 65.0 0.0 1.4e-17 64.0 0.0 1.6 1 0 0 1 1 1 1 ATP cone domain Mito_carr PF00153.27 OAG42365.1 - 8e-67 221.2 4.5 2.2e-23 82.0 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein UCR_14kD PF02271.16 OAG42366.1 - 5.9e-44 148.1 0.0 6.9e-44 147.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit HhH-GPD PF00730.25 OAG42367.1 - 1.6e-14 54.3 0.0 2.9e-14 53.4 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Recep_L_domain PF01030.24 OAG42368.1 - 1.4e-08 34.8 4.9 0.0032 17.6 0.0 3.8 1 1 3 4 4 4 3 Receptor L domain Ecm33 PF12454.8 OAG42368.1 - 0.00014 21.9 0.1 0.00081 19.5 0.1 2.3 2 0 0 2 2 2 1 GPI-anchored cell wall organization protein LRR_5 PF13306.6 OAG42368.1 - 0.00048 20.1 2.1 0.044 13.7 0.0 2.5 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 OAG42368.1 - 0.08 13.4 15.2 1.9 9.0 0.0 5.0 3 1 2 5 5 5 0 Leucine Rich repeats (2 copies) Herpes_capsid PF06112.11 OAG42368.1 - 3.7 7.6 9.8 10 6.1 9.8 1.7 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Abhydrolase_1 PF00561.20 OAG42369.1 - 9.1e-11 41.9 0.0 6.4e-10 39.1 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAG42369.1 - 3.1e-08 33.2 0.0 8.9e-08 31.7 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OAG42369.1 - 1.4e-07 32.3 0.1 1.9e-07 31.9 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.12 OAG42369.1 - 1.9e-07 30.1 0.0 0.0053 15.5 0.0 2.7 2 1 0 2 2 2 2 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.21 OAG42369.1 - 4.1e-06 26.4 0.1 0.0022 17.5 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family DLH PF01738.18 OAG42369.1 - 0.00036 20.2 0.0 0.00067 19.3 0.0 1.4 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S15 PF02129.18 OAG42369.1 - 0.00087 19.0 0.1 0.0023 17.6 0.1 1.6 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) BAAT_C PF08840.11 OAG42369.1 - 0.0016 18.4 0.0 0.003 17.5 0.0 1.4 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal PAF-AH_p_II PF03403.13 OAG42369.1 - 0.098 11.1 0.0 0.22 10.0 0.0 1.5 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II CorA PF01544.18 OAG42370.1 - 0.0001 21.8 1.7 0.00013 21.4 0.7 1.6 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein Zn_clus PF00172.18 OAG42371.1 - 2.9e-08 33.7 13.2 5.8e-08 32.7 13.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAG42371.1 - 4.5e-08 32.5 0.0 7.5e-08 31.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 OAG42372.1 - 3e-32 111.9 17.1 6.1e-32 110.9 16.6 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily UPF0242 PF06785.11 OAG42372.1 - 0.017 15.2 0.0 0.64 10.1 0.1 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Anoctamin PF04547.12 OAG42372.1 - 0.074 11.9 3.4 0.12 11.2 0.7 2.3 2 1 0 2 2 2 0 Calcium-activated chloride channel DUF3094 PF11293.8 OAG42372.1 - 0.24 11.2 6.9 3.5 7.4 0.3 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3094) APH PF01636.23 OAG42373.1 - 6.8e-05 22.9 0.2 0.00027 21.0 0.2 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Cytochrom_B561 PF03188.16 OAG42374.1 - 2e-05 24.7 7.5 2e-05 24.7 7.5 2.0 2 1 1 3 3 3 2 Eukaryotic cytochrome b561 PRA1 PF03208.19 OAG42374.1 - 4.7 6.8 7.9 0.53 9.9 0.4 2.6 2 1 1 3 3 3 0 PRA1 family protein DUF2427 PF10348.9 OAG42374.1 - 5.3 6.9 7.2 12 5.7 6.1 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF2427) HET PF06985.11 OAG42375.1 - 7.8e-31 107.4 1.7 1.4e-30 106.6 1.7 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Oxidored_molyb PF00174.19 OAG42376.1 - 5.1e-44 149.9 0.0 1e-43 148.9 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 OAG42376.1 - 1.8e-19 70.1 3.4 3.5e-19 69.2 3.4 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain SLBB PF10531.9 OAG42376.1 - 0.071 13.0 0.0 0.69 9.8 0.0 2.2 2 0 0 2 2 2 0 SLBB domain Catalase PF00199.19 OAG42377.1 - 1.1e-161 538.3 0.0 1.3e-161 538.0 0.0 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 OAG42377.1 - 3.3e-10 40.0 0.2 7.8e-10 38.8 0.2 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive Fungal_trans PF04082.18 OAG42378.1 - 4.6e-14 52.1 0.0 6.9e-14 51.5 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Herpes_capsid PF06112.11 OAG42378.1 - 6.1 6.9 8.6 11 6.1 8.6 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Band_7 PF01145.25 OAG42379.1 - 2.5e-30 105.8 1.4 4.6e-30 104.9 1.4 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_C PF16200.5 OAG42379.1 - 7.1e-25 86.8 2.3 2e-24 85.4 2.3 1.9 1 0 0 1 1 1 1 C-terminal region of band_7 Band_7_1 PF13421.6 OAG42379.1 - 0.044 13.5 0.0 0.087 12.5 0.0 1.5 1 0 0 1 1 1 0 SPFH domain-Band 7 family Pox_A11 PF05061.13 OAG42379.1 - 0.049 12.9 0.2 0.077 12.3 0.2 1.3 1 0 0 1 1 1 0 Poxvirus A11 Protein DRTGG PF07085.12 OAG42379.1 - 0.073 12.9 1.3 0.76 9.6 0.1 2.7 1 1 0 3 3 3 0 DRTGG domain GSH-S_N PF02951.14 OAG42379.1 - 0.13 12.4 0.1 0.31 11.2 0.1 1.6 1 1 0 1 1 1 0 Prokaryotic glutathione synthetase, N-terminal domain Hira PF07569.11 OAG42380.1 - 7.5e-85 284.2 0.0 2.3e-84 282.5 0.0 1.9 2 0 0 2 2 2 1 TUP1-like enhancer of split WD40 PF00400.32 OAG42380.1 - 1.6e-28 98.3 15.8 1.7e-05 25.5 0.0 8.1 7 1 1 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG42380.1 - 1e-13 51.3 0.0 0.068 13.5 0.0 5.9 4 2 2 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain HIRA_B PF09453.10 OAG42380.1 - 7.3e-08 32.1 0.2 2.1e-07 30.6 0.2 1.9 1 0 0 1 1 1 1 HIRA B motif Ge1_WD40 PF16529.5 OAG42380.1 - 0.00084 18.4 0.2 1 8.2 0.0 4.5 4 2 2 6 6 6 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 OAG42380.1 - 0.012 15.6 3.6 0.62 10.1 0.3 3.9 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Glyco_transf_15 PF01793.16 OAG42381.1 - 2e-96 323.1 0.5 2.6e-96 322.7 0.5 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase DUF1908 PF08926.11 OAG42381.1 - 0.63 9.1 3.8 1 8.4 3.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1908) YchF-GTPase_C PF06071.13 OAG42382.1 - 1.5e-35 121.3 0.3 3.7e-35 120.0 0.3 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 OAG42382.1 - 1.3e-15 57.4 0.0 3.8e-15 56.0 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OAG42382.1 - 0.00053 19.6 0.0 0.0011 18.5 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.21 OAG42382.1 - 0.0023 17.9 0.0 0.0072 16.4 0.0 1.8 2 0 0 2 2 2 1 TGS domain SecA_PP_bind PF01043.20 OAG42382.1 - 0.23 12.1 0.9 0.39 11.4 0.1 1.9 2 1 0 2 2 2 0 SecA preprotein cross-linking domain AAA_23 PF13476.6 OAG42382.1 - 3.1 8.3 5.9 39 4.7 5.4 2.4 1 1 0 1 1 1 0 AAA domain adh_short PF00106.25 OAG42383.1 - 5.8e-21 74.8 0.0 1.6e-18 66.9 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAG42383.1 - 2.6e-11 43.5 0.1 7.6e-10 38.7 0.0 2.1 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG42383.1 - 2e-08 34.4 0.1 3e-08 33.8 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG42383.1 - 0.01 15.3 0.0 0.013 15.0 0.0 1.1 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family WD40 PF00400.32 OAG42384.1 - 2.9e-08 34.2 21.3 0.001 19.9 0.2 4.7 4 1 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG42384.1 - 8.1e-07 29.3 0.1 0.26 11.6 0.0 4.5 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Mito_fiss_reg PF05308.11 OAG42384.1 - 0.0017 18.5 0.3 0.0029 17.7 0.3 1.4 1 0 0 1 1 1 1 Mitochondrial fission regulator Nup160 PF11715.8 OAG42384.1 - 0.063 11.9 3.5 2.8 6.5 0.1 3.1 3 1 1 4 4 4 0 Nucleoporin Nup120/160 PQQ_3 PF13570.6 OAG42384.1 - 0.086 13.4 0.2 71 4.1 0.0 3.9 4 1 1 5 5 5 0 PQQ-like domain Ribosomal_L13 PF00572.18 OAG42385.1 - 8.3e-11 42.2 0.0 8e-09 35.8 0.0 2.4 1 1 0 1 1 1 1 Ribosomal protein L13 PSCyt3 PF07627.11 OAG42386.1 - 0.063 13.6 1.2 0.13 12.5 1.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1588) WYL_3 PF18488.1 OAG42386.1 - 0.12 12.8 0.0 0.18 12.2 0.0 1.2 1 0 0 1 1 1 0 WYL domain OrfB_Zn_ribbon PF07282.11 OAG42386.1 - 0.13 12.2 1.4 0.26 11.2 1.4 1.6 1 1 0 1 1 1 0 Putative transposase DNA-binding domain CAP_N PF01213.19 OAG42386.1 - 0.54 9.7 3.7 0.77 9.2 3.7 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Cytochrom_B558a PF05038.13 OAG42386.1 - 1.8 8.1 4.4 3 7.4 4.4 1.3 1 0 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit CDP-OH_P_transf PF01066.21 OAG42387.1 - 1.2e-17 64.4 0.2 1.2e-17 64.4 0.2 3.5 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase F-box PF00646.33 OAG42388.1 - 0.056 13.3 0.0 0.29 11.1 0.0 2.3 2 0 0 2 2 2 0 F-box domain PhyH PF05721.13 OAG42389.1 - 3e-20 73.4 0.2 3.9e-20 73.0 0.2 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 OAG42389.1 - 0.0022 18.4 0.0 0.0076 16.6 0.0 1.9 1 1 1 2 2 2 1 Putative 2OG-Fe(II) oxygenase Fungal_trans_2 PF11951.8 OAG42390.1 - 1.2e-13 50.7 2.9 4.4e-07 29.0 0.4 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain DUF5543 PF17697.1 OAG42390.1 - 0.12 12.6 0.1 0.3 11.4 0.1 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5543) NAD_binding_10 PF13460.6 OAG42391.1 - 9.8e-06 25.6 0.0 1.3e-05 25.2 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 OAG42391.1 - 0.0073 15.5 0.0 0.02 14.1 0.0 1.7 2 0 0 2 2 2 1 Male sterility protein Semialdhyde_dh PF01118.24 OAG42391.1 - 0.013 16.0 0.0 0.026 15.0 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 OAG42391.1 - 0.019 15.2 0.0 0.051 13.8 0.0 1.6 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 OAG42391.1 - 0.022 14.2 0.0 0.038 13.5 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 OAG42391.1 - 0.17 11.0 0.0 0.29 10.2 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 OAG42391.1 - 0.2 10.6 0.0 0.27 10.2 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Zn_clus PF00172.18 OAG42392.1 - 9.6e-06 25.6 9.3 2e-05 24.6 9.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Integrase_H2C2 PF17921.1 OAG42392.1 - 0.23 11.6 1.0 0.45 10.7 1.0 1.5 1 0 0 1 1 1 0 Integrase zinc binding domain Sugar_tr PF00083.24 OAG42393.1 - 2.5e-71 240.9 19.5 9.3e-44 150.0 2.9 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 OAG42393.1 - 1.4e-09 37.3 35.0 1.4e-09 37.3 35.0 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2574 PF10836.8 OAG42393.1 - 0.019 14.8 0.1 0.054 13.4 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2574) Ribosomal_L24e PF01246.20 OAG42394.1 - 6.3e-05 23.1 0.8 0.00017 21.7 0.8 1.8 1 0 0 1 1 1 1 Ribosomal protein L24e Curto_V3 PF07436.11 OAG42394.1 - 1.7 9.1 3.4 1.3 9.5 1.2 1.9 1 1 1 2 2 2 0 Curtovirus V3 protein F-box-like PF12937.7 OAG42395.1 - 0.0001 22.1 0.9 0.00047 20.0 1.4 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 OAG42395.1 - 0.0046 16.8 0.5 0.011 15.6 0.5 1.6 1 0 0 1 1 1 1 F-box domain DUF3425 PF11905.8 OAG42396.1 - 1.6e-15 57.2 0.0 3.4e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) FAD_binding_3 PF01494.19 OAG42397.1 - 2.6e-17 63.1 0.1 1e-16 61.2 0.1 1.8 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 OAG42397.1 - 2.1e-09 37.0 0.1 3.9e-09 36.2 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAG42397.1 - 1.3e-07 31.6 5.5 7.1e-05 22.6 4.4 2.1 1 1 1 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OAG42397.1 - 4.7e-07 29.2 1.0 7.4e-07 28.6 1.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 OAG42397.1 - 4.8e-07 29.9 1.7 1.2e-06 28.6 1.7 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 OAG42397.1 - 7.4e-05 21.6 1.7 0.00034 19.5 0.9 1.9 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 OAG42397.1 - 7.8e-05 22.2 0.9 0.00012 21.6 0.9 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 OAG42397.1 - 0.00017 22.1 0.9 0.00066 20.2 1.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OAG42397.1 - 0.0006 19.0 2.6 0.00099 18.3 2.6 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Trp_halogenase PF04820.14 OAG42397.1 - 0.003 16.5 1.1 0.013 14.4 0.5 1.9 1 1 0 2 2 2 1 Tryptophan halogenase Amino_oxidase PF01593.24 OAG42397.1 - 0.017 14.4 0.1 1.7 7.8 0.0 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.21 OAG42397.1 - 0.017 14.4 1.1 0.034 13.4 0.4 1.7 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 OAG42397.1 - 0.045 13.0 0.4 0.069 12.4 0.4 1.3 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.12 OAG42397.1 - 0.052 12.6 0.1 0.98 8.4 0.1 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 OAG42397.1 - 0.13 12.3 3.0 4.2 7.3 0.6 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding DUF3084 PF11283.8 OAG42397.1 - 0.16 12.0 1.7 0.39 10.7 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3084) DUF3342 PF11822.8 OAG42397.1 - 0.16 12.2 0.0 5.7 7.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3342) SE PF08491.10 OAG42397.1 - 0.24 10.4 0.0 0.61 9.1 0.0 1.6 2 0 0 2 2 2 0 Squalene epoxidase Pyr_redox_3 PF13738.6 OAG42397.1 - 0.3 10.3 0.9 0.66 9.2 0.9 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 OAG42397.1 - 0.81 9.3 2.6 1.5 8.5 2.6 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA AA_permease_2 PF13520.6 OAG42398.1 - 4e-49 167.6 52.7 5.4e-49 167.2 52.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAG42398.1 - 2.5e-21 75.8 46.2 3.5e-21 75.4 46.2 1.0 1 0 0 1 1 1 1 Amino acid permease PetN PF03742.14 OAG42398.1 - 0.0038 17.1 2.4 0.025 14.4 2.4 2.6 1 0 0 1 1 1 1 PetN LapA_dom PF06305.11 OAG42398.1 - 4.1 7.3 9.2 1.9 8.4 0.4 3.9 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain Pam16 PF03656.13 OAG42399.1 - 3.5e-08 33.5 0.1 7.1e-08 32.5 0.1 1.5 1 1 0 1 1 1 1 Pam16 DnaJ PF00226.31 OAG42399.1 - 5.7e-05 23.2 0.0 9e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain DUF3918 PF13056.6 OAG42399.1 - 0.0073 15.9 0.6 0.016 14.9 0.6 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3918) Abhydrolase_1 PF00561.20 OAG42400.1 - 1.6e-10 41.0 0.1 0.00013 21.7 0.0 3.1 2 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG42400.1 - 6.9e-10 39.9 1.7 9.3e-10 39.5 1.7 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG42400.1 - 1.6e-06 27.5 0.0 0.0031 16.8 0.0 2.5 2 1 0 2 2 2 2 Serine aminopeptidase, S33 zf-C2H2 PF00096.26 OAG42401.1 - 0.016 15.7 3.2 0.043 14.3 3.2 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type DNA_pol_phi PF04931.13 OAG42401.1 - 0.4 8.7 3.7 0.68 8.0 3.7 1.3 1 0 0 1 1 1 0 DNA polymerase phi DUF3602 PF12223.8 OAG42402.1 - 4.6e-11 43.2 11.7 0.002 18.7 1.6 3.4 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) Fungal_trans_2 PF11951.8 OAG42403.1 - 6.8e-35 120.6 1.9 1.5e-34 119.5 1.9 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Abhydrolase_3 PF07859.13 OAG42404.1 - 2.1e-20 73.5 0.0 3e-20 73.0 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 OAG42404.1 - 1.9e-12 46.8 0.4 4e-12 45.7 0.0 1.7 2 1 0 2 2 2 1 Steryl acetyl hydrolase COesterase PF00135.28 OAG42404.1 - 0.25 10.2 0.3 0.55 9.0 0.0 1.7 2 0 0 2 2 2 0 Carboxylesterase family Amino_oxidase PF01593.24 OAG42405.1 - 5.4e-56 190.8 0.7 6.3e-56 190.5 0.7 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OAG42405.1 - 4e-12 46.2 0.4 1.1e-11 44.7 0.4 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAG42405.1 - 1.7e-08 34.5 2.0 2.3e-08 34.0 2.0 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 OAG42405.1 - 1.1e-06 28.0 0.0 2e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 OAG42405.1 - 3.2e-06 26.5 0.2 6e-06 25.6 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 OAG42405.1 - 3.6e-06 26.6 0.1 7.2e-06 25.6 0.1 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 OAG42405.1 - 6.2e-05 21.9 0.0 0.00011 21.0 0.0 1.4 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.14 OAG42405.1 - 0.00012 21.5 0.0 0.00025 20.4 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAG42405.1 - 0.00018 22.0 0.1 0.0004 20.9 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 OAG42405.1 - 0.00069 19.0 0.3 0.0015 17.8 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 OAG42405.1 - 0.00097 18.3 0.1 0.0019 17.3 0.1 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein GIDA PF01134.22 OAG42405.1 - 0.021 13.9 0.1 0.038 13.1 0.1 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_9 PF13454.6 OAG42405.1 - 0.06 13.3 0.2 0.55 10.2 0.1 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 OAG42405.1 - 0.078 12.2 0.1 0.31 10.2 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lactamase_B PF00753.27 OAG42406.1 - 5.9e-05 23.2 1.2 0.0005 20.1 0.3 2.3 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OAG42406.1 - 0.026 14.0 0.0 0.048 13.2 0.0 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Fer4_19 PF06902.11 OAG42406.1 - 0.29 11.2 1.0 0.5 10.5 0.1 1.9 2 0 0 2 2 2 0 Divergent 4Fe-4S mono-cluster Abhydrolase_3 PF07859.13 OAG42407.1 - 9.6e-21 74.6 0.0 1.6e-20 73.9 0.0 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Kinesin PF00225.23 OAG42408.1 - 2.9e-51 174.4 0.0 7.4e-28 97.4 0.0 2.2 2 0 0 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 OAG42408.1 - 6e-12 45.7 0.0 1.1e-11 44.9 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding DUF2550 PF10739.9 OAG42408.1 - 0.067 13.2 0.2 2.8 8.0 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2550) Nop53 PF07767.11 OAG42408.1 - 0.12 11.7 0.7 0.19 11.1 0.7 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) AA_permease PF00324.21 OAG42409.1 - 1.4e-96 324.0 26.2 1.6e-96 323.8 26.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAG42409.1 - 1.5e-19 70.1 25.8 2e-19 69.7 25.8 1.1 1 0 0 1 1 1 1 Amino acid permease DUF1772 PF08592.11 OAG42409.1 - 0.013 15.8 2.0 0.013 15.8 2.0 3.3 2 1 2 4 4 4 0 Domain of unknown function (DUF1772) AA_permease PF00324.21 OAG42410.1 - 0.00027 19.7 4.2 0.00032 19.4 4.2 1.1 1 0 0 1 1 1 1 Amino acid permease Arginase PF00491.21 OAG42411.1 - 8.2e-83 278.1 0.5 1.1e-82 277.8 0.5 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 OAG42411.1 - 0.041 14.1 0.1 0.064 13.5 0.1 1.2 1 0 0 1 1 1 0 UPF0489 domain Cyt-b5 PF00173.28 OAG42412.1 - 3.6e-09 36.6 0.1 4.3e-09 36.4 0.1 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain RRM_1 PF00076.22 OAG42413.1 - 1.8e-59 197.5 0.1 5.4e-18 64.6 0.0 5.6 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 OAG42413.1 - 1.4e-05 25.4 0.2 10 6.3 0.0 5.8 4 2 2 6 6 6 2 Cytosolic domain of 10TM putative phosphate transporter RRM_Rrp7 PF17799.1 OAG42413.1 - 9e-05 22.3 0.4 1.3 8.8 0.0 3.7 2 2 2 4 4 4 2 Rrp7 RRM-like N-terminal domain RRM_5 PF13893.6 OAG42413.1 - 0.0052 16.4 0.0 3.4 7.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Actino_peptide PF14408.6 OAG42413.1 - 0.04 14.0 0.0 17 5.6 0.0 3.0 2 0 0 2 2 2 0 Ribosomally synthesised peptide in actinomycetes RRM_7 PF16367.5 OAG42413.1 - 0.13 12.4 0.0 44 4.3 0.0 3.6 3 0 0 3 3 3 0 RNA recognition motif Rad10 PF03834.14 OAG42414.1 - 5.7e-49 164.9 0.2 1e-48 164.1 0.2 1.4 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.6 OAG42414.1 - 0.0056 17.3 0.0 0.012 16.2 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH PF00633.23 OAG42414.1 - 0.0086 15.9 0.1 0.02 14.8 0.1 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_2 PF12826.7 OAG42414.1 - 0.017 15.2 0.6 0.086 13.0 0.0 2.4 3 0 0 3 3 3 0 Helix-hairpin-helix motif ssDNA_DBD PF18333.1 OAG42414.1 - 0.022 14.9 0.5 0.055 13.6 0.5 1.6 1 0 0 1 1 1 0 Non-canonical single-stranded DNA-binding domain StbA PF06406.11 OAG42416.1 - 0.064 12.5 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 StbA protein Peptidase_M28 PF04389.17 OAG42417.1 - 6.5e-35 120.6 0.0 1e-34 120.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 OAG42417.1 - 0.12 12.1 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 Lipase_GDSL PF00657.22 OAG42419.1 - 1.1e-07 32.1 0.0 1.4e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 OAG42419.1 - 0.012 16.0 5.7 0.032 14.6 5.7 1.8 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Otopetrin PF03189.13 OAG42420.1 - 2.5 6.8 5.0 4.1 6.1 5.0 1.3 1 0 0 1 1 1 0 Otopetrin DUF1682 PF07946.14 OAG42420.1 - 4.6 6.4 17.7 7.9 5.6 17.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Ank_3 PF13606.6 OAG42421.1 - 2e-05 24.6 0.1 0.12 13.0 0.0 2.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 OAG42421.1 - 2.4e-05 24.8 0.0 3.4e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAG42421.1 - 0.0036 17.8 0.0 0.7 10.6 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 OAG42421.1 - 0.023 15.1 0.1 14 6.4 0.0 3.0 3 0 0 3 3 3 0 Ankyrin repeat AA_permease_2 PF13520.6 OAG42423.1 - 3.7e-43 147.9 50.6 5.1e-43 147.5 50.6 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAG42423.1 - 5.5e-25 87.9 46.6 7.2e-25 87.5 46.6 1.0 1 0 0 1 1 1 1 Amino acid permease Phenol_monoox PF04663.12 OAG42423.1 - 1.6 8.9 5.4 3.6 7.8 0.0 3.3 3 0 0 3 3 3 0 Phenol hydroxylase conserved region Ammonium_transp PF00909.21 OAG42424.1 - 3e-73 246.8 19.3 3.4e-73 246.6 19.3 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DUF302 PF03625.14 OAG42426.1 - 0.00041 20.2 0.0 0.0007 19.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF302 Thr_synth_N PF14821.6 OAG42427.1 - 2.3e-24 85.4 0.0 6.1e-24 84.0 0.0 1.8 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.25 OAG42427.1 - 1.7e-18 67.1 0.0 8.7e-18 64.7 0.0 1.9 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF4713 PF15831.5 OAG42428.1 - 0.49 10.9 4.7 0.61 10.6 0.7 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4713) Asp PF00026.23 OAG42429.1 - 2.7e-60 204.5 3.9 3.2e-60 204.2 3.9 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OAG42429.1 - 1.3e-06 28.8 0.7 0.021 15.1 0.1 2.7 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 OAG42429.1 - 0.00013 22.5 4.7 0.42 11.3 0.7 3.4 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 OAG42429.1 - 0.08 13.5 0.8 14 6.3 0.1 3.4 3 1 0 3 3 3 0 gag-polyprotein putative aspartyl protease ParA PF10609.9 OAG42430.1 - 1.7e-97 325.7 0.0 2e-97 325.5 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 OAG42430.1 - 1.5e-07 31.5 0.0 3.3e-07 30.4 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.15 OAG42430.1 - 8.1e-06 25.2 0.6 0.0005 19.3 0.2 2.8 1 1 1 3 3 3 1 Anion-transporting ATPase AAA_31 PF13614.6 OAG42430.1 - 1.4e-05 25.1 0.0 6.3e-05 23.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_26 PF13500.6 OAG42430.1 - 0.0045 16.8 0.0 0.14 12.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain Fer4_NifH PF00142.18 OAG42430.1 - 0.017 14.6 0.0 0.91 8.9 0.0 2.2 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_30 PF13604.6 OAG42430.1 - 0.026 14.2 0.0 0.038 13.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 OAG42430.1 - 0.036 14.0 0.0 0.075 12.9 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase MipZ PF09140.11 OAG42430.1 - 0.08 12.2 0.0 0.19 11.0 0.0 1.6 1 1 0 1 1 1 0 ATPase MipZ AAA_25 PF13481.6 OAG42430.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 OAG42430.1 - 0.14 12.7 0.0 0.23 12.0 0.0 1.4 1 1 0 1 1 1 0 AAA domain CLP1_P PF16575.5 OAG42430.1 - 0.15 11.8 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop PEMT PF04191.13 OAG42431.1 - 1.4e-61 205.4 8.2 5.9e-38 129.5 0.5 2.5 2 0 0 2 2 2 2 Phospholipid methyltransferase HECW_N PF16562.5 OAG42431.1 - 0.019 14.8 0.0 0.05 13.4 0.0 1.7 1 0 0 1 1 1 0 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 Q_salvage PF10343.9 OAG42432.1 - 1.2e-123 412.2 0.0 1.4e-123 412.0 0.0 1.0 1 0 0 1 1 1 1 Potential Queuosine, Q, salvage protein family ThiF PF00899.21 OAG42433.1 - 4.7e-73 245.5 0.0 6.6e-73 245.1 0.0 1.1 1 0 0 1 1 1 1 ThiF family UAE_UbL PF14732.6 OAG42433.1 - 1.3e-19 70.6 1.5 1.3e-19 70.6 1.5 2.0 2 0 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.9 OAG42433.1 - 1.8e-12 47.7 1.2 1.5e-07 31.6 0.0 2.6 1 1 1 2 2 2 2 Ubiquitin-activating enzyme active site NAD_binding_7 PF13241.6 OAG42433.1 - 0.0022 18.4 0.0 0.0095 16.4 0.0 2.0 1 0 0 1 1 1 1 Putative NAD(P)-binding LMBR1 PF04791.16 OAG42433.1 - 0.015 14.2 0.4 0.023 13.6 0.4 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Pyr_redox PF00070.27 OAG42433.1 - 0.016 15.8 0.2 3.1 8.4 0.1 2.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 OAG42433.1 - 0.022 14.8 0.0 0.05 13.7 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Kinesin_assoc PF16183.5 OAG42433.1 - 0.062 13.4 0.2 0.12 12.5 0.2 1.4 1 0 0 1 1 1 0 Kinesin-associated potato_inhibit PF00280.18 OAG42433.1 - 0.21 12.3 1.5 5 7.9 0.1 3.0 3 0 0 3 3 3 0 Potato inhibitor I family Skp1_POZ PF03931.15 OAG42434.1 - 5.5e-12 45.7 0.0 7.1e-12 45.3 0.0 1.1 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain BTB PF00651.31 OAG42434.1 - 0.00083 19.6 0.0 0.0011 19.2 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain tRNA_int_end_N2 PF12928.7 OAG42435.1 - 4.5e-21 74.8 0.2 9.7e-21 73.7 0.2 1.6 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.14 OAG42435.1 - 0.0055 16.3 0.0 0.013 15.1 0.0 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, N-terminal domain Aminotran_5 PF00266.19 OAG42436.1 - 2.2e-18 66.4 0.0 5.6e-18 65.0 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 OAG42436.1 - 0.0005 19.3 0.0 0.00088 18.5 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 OAG42436.1 - 0.046 13.0 0.0 7.2 5.8 0.0 2.2 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 OAG42436.1 - 0.053 12.1 0.0 0.37 9.3 0.0 2.1 2 1 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme YajC PF02699.15 OAG42436.1 - 0.12 12.2 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Preprotein translocase subunit FAD_binding_4 PF01565.23 OAG42438.1 - 1e-23 83.6 5.2 1.2e-23 83.4 3.2 2.0 2 0 0 2 2 2 1 FAD binding domain zf-RING_11 PF17123.5 OAG42438.1 - 3.1e-09 36.4 3.1 6.4e-09 35.4 3.1 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 OAG42438.1 - 1.4e-08 34.9 0.6 2.6e-08 34.1 0.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 OAG42438.1 - 0.00018 21.3 0.3 0.00033 20.5 0.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OAG42438.1 - 0.00057 19.7 0.3 0.0011 18.8 0.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAG42438.1 - 0.0033 17.4 0.9 0.0062 16.5 0.9 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 OAG42438.1 - 0.0039 17.1 0.5 0.0069 16.3 0.5 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 OAG42438.1 - 0.01 16.1 1.2 0.029 14.6 1.2 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger domain PHD PF00628.29 OAG42438.1 - 0.53 10.2 2.0 1.2 9.1 0.2 2.2 2 0 0 2 2 2 0 PHD-finger MFS_1 PF07690.16 OAG42439.1 - 4.5e-27 94.9 17.0 6.5e-27 94.4 17.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Wyosine_form PF08608.12 OAG42440.1 - 1.3e-24 86.3 0.0 3.1e-24 85.1 0.0 1.7 1 0 0 1 1 1 1 Wyosine base formation Radical_SAM PF04055.21 OAG42440.1 - 6.5e-19 68.9 0.1 1.9e-18 67.4 0.1 1.8 1 1 0 1 1 1 1 Radical SAM superfamily Flavodoxin_1 PF00258.25 OAG42440.1 - 2.7e-08 34.1 0.0 4.4e-07 30.2 0.0 2.6 1 1 0 1 1 1 1 Flavodoxin Flavodoxin_3 PF12641.7 OAG42440.1 - 0.053 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Flavodoxin domain NBP1 PF08537.10 OAG42440.1 - 0.13 11.7 0.1 0.2 11.0 0.1 1.2 1 0 0 1 1 1 0 Fungal Nap binding protein NBP1 AMP-binding PF00501.28 OAG42442.1 - 4.7e-88 295.6 0.0 5.9e-88 295.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG42442.1 - 2.7e-13 50.7 2.0 6.9e-13 49.4 2.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain LapA_dom PF06305.11 OAG42443.1 - 0.084 12.7 1.4 1.1 9.1 0.6 2.4 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain PhyH PF05721.13 OAG42444.1 - 9.3e-10 39.1 0.0 1.4e-09 38.5 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF4448 PF14610.6 OAG42446.1 - 0.1 12.4 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DUF3093 PF11292.8 OAG42446.1 - 1.5 9.1 7.8 0.089 13.1 2.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3093) F-box-like PF12937.7 OAG42447.1 - 0.042 13.7 0.3 0.089 12.7 0.3 1.6 1 0 0 1 1 1 0 F-box-like FlxA PF14282.6 OAG42448.1 - 1.1 9.3 5.4 3 7.9 5.4 1.7 1 0 0 1 1 1 0 FlxA-like protein TRAP_alpha PF03896.16 OAG42449.1 - 4e-09 36.1 0.0 5.3e-09 35.7 0.0 1.1 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit STAG PF08514.11 OAG42450.1 - 4.7e-34 116.7 0.2 2.2e-33 114.5 0.2 2.3 1 0 0 1 1 1 1 STAG domain HEAT_2 PF13646.6 OAG42450.1 - 0.00074 19.9 4.2 0.039 14.3 0.3 4.1 3 1 1 4 4 4 1 HEAT repeats YL1 PF05764.13 OAG42450.1 - 0.0048 17.1 14.1 0.0048 17.1 14.1 4.5 4 1 0 4 4 4 1 YL1 nuclear protein DUF4446 PF14584.6 OAG42450.1 - 0.11 12.5 0.6 0.31 11.0 0.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) UreD PF01774.17 OAG42451.1 - 3e-70 236.5 0.0 3.7e-70 236.1 0.0 1.1 1 0 0 1 1 1 1 UreD urease accessory protein UPRTase PF14681.6 OAG42452.1 - 1e-69 234.1 0.0 8.7e-69 231.1 0.0 1.9 1 1 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 OAG42452.1 - 9.9e-07 28.4 0.1 2.2e-06 27.3 0.1 1.5 1 1 0 1 1 1 1 Phosphoribosyl transferase domain CRCB PF02537.15 OAG42453.1 - 1.4e-36 124.7 12.2 7.5e-23 80.7 6.6 2.4 2 0 0 2 2 2 2 CrcB-like protein, Camphor Resistance (CrcB) Prion_bPrPp PF11587.8 OAG42453.1 - 4.4 7.2 5.4 1.8 8.5 1.9 2.2 2 0 0 2 2 2 0 Major prion protein bPrPp - N terminal KRE1 PF17056.5 OAG42454.1 - 9.6e-11 41.3 0.1 1.9e-10 40.3 0.1 1.4 1 0 0 1 1 1 1 Killer toxin-resistance protein 1 RNA_pol_Rpc4 PF05132.14 OAG42455.1 - 1.5e-31 109.8 0.0 1.5e-31 109.8 0.0 3.7 3 1 0 3 3 3 1 RNA polymerase III RPC4 Zn_clus PF00172.18 OAG42456.1 - 0.00097 19.2 11.6 0.0018 18.4 11.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cyclin_N PF00134.23 OAG42457.1 - 3.3e-44 149.7 0.2 6.5e-44 148.7 0.2 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 OAG42457.1 - 1.5e-34 118.7 0.1 4.4e-34 117.1 0.1 1.9 1 0 0 1 1 1 1 Cyclin, C-terminal domain ECM1 PF05782.11 OAG42457.1 - 0.082 11.8 0.5 0.16 10.8 0.0 1.7 1 1 0 1 1 1 0 Extracellular matrix protein 1 (ECM1) OB_NTP_bind PF07717.16 OAG42458.1 - 2.9e-17 62.8 0.0 5.6e-17 61.9 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 OAG42458.1 - 1.1e-15 57.9 0.0 3.5e-15 56.2 0.0 1.9 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 OAG42458.1 - 6.2e-14 52.3 0.0 1.3e-13 51.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RWD PF05773.22 OAG42458.1 - 1.1e-11 45.0 0.0 2.3e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 RWD domain DEAD PF00270.29 OAG42458.1 - 2.4e-08 33.9 0.5 4.8e-08 33.0 0.5 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_29 PF13555.6 OAG42458.1 - 0.00057 19.6 0.0 0.0015 18.3 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_19 PF13245.6 OAG42458.1 - 0.00067 20.0 0.1 0.0017 18.7 0.1 1.7 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 OAG42458.1 - 0.001 18.5 0.0 0.0022 17.4 0.0 1.5 1 0 0 1 1 1 1 KaiC AAA_22 PF13401.6 OAG42458.1 - 0.0031 17.8 0.6 0.011 16.0 0.6 1.9 1 1 0 1 1 1 1 AAA domain AAA_23 PF13476.6 OAG42458.1 - 0.0035 17.9 0.0 0.0091 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 OAG42458.1 - 0.0036 17.0 0.2 0.015 15.0 0.1 2.0 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 OAG42458.1 - 0.01 15.3 0.2 0.018 14.5 0.2 1.3 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 OAG42458.1 - 0.031 13.9 0.0 0.079 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain UBA PF00627.31 OAG42458.1 - 0.055 13.4 0.0 9.7 6.2 0.0 2.7 2 0 0 2 2 2 0 UBA/TS-N domain FtsK_SpoIIIE PF01580.18 OAG42458.1 - 0.07 12.5 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Zot PF05707.12 OAG42458.1 - 0.093 12.4 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) PhoH PF02562.16 OAG42458.1 - 0.1 12.1 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Sigma54_activat PF00158.26 OAG42458.1 - 0.16 11.6 0.1 1.3 8.7 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain HOIP-UBA PF16678.5 OAG42458.1 - 0.25 11.4 2.0 28 4.7 0.0 3.1 3 0 0 3 3 2 0 HOIP UBA domain pair DUF3176 PF11374.8 OAG42459.1 - 1.6e-18 66.8 5.6 2.9e-18 66.0 4.4 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) Zn_clus PF00172.18 OAG42460.1 - 0.026 14.6 11.3 0.061 13.4 11.3 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain TRAF_BIRC3_bd PF16673.5 OAG42460.1 - 0.12 12.1 0.5 0.27 11.0 0.5 1.5 1 0 0 1 1 1 0 TNF receptor-associated factor BIRC3 binding domain Shugoshin_N PF07558.11 OAG42460.1 - 0.15 11.9 1.3 0.43 10.5 1.3 1.7 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region MFS_1 PF07690.16 OAG42461.1 - 2.6e-42 145.0 49.7 2.6e-42 145.0 49.7 2.3 3 0 0 3 3 3 1 Major Facilitator Superfamily TRI12 PF06609.13 OAG42461.1 - 3.7e-11 42.2 22.3 5.4e-11 41.6 22.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF4199 PF13858.6 OAG42461.1 - 0.031 14.7 0.4 0.031 14.7 0.4 4.3 5 0 0 5 5 5 0 Protein of unknown function (DUF4199) DUF4029 PF13221.6 OAG42461.1 - 0.058 14.1 2.2 0.075 13.7 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4029) GST_N_2 PF13409.6 OAG42463.1 - 1.2e-20 73.6 0.7 1.6e-19 70.0 0.0 2.8 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAG42463.1 - 4.6e-16 58.6 0.0 1.4e-15 57.1 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OAG42463.1 - 1.1e-05 25.5 0.0 3.3e-05 24.0 0.0 2.1 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OAG42463.1 - 0.0011 19.2 0.1 0.0027 17.8 0.0 1.8 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 OAG42463.1 - 0.0019 18.8 0.0 0.0036 17.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Zn_peptidase PF04228.13 OAG42463.1 - 0.048 13.1 0.2 0.11 11.9 0.0 1.6 2 0 0 2 2 2 0 Putative neutral zinc metallopeptidase Phyto_Pns9_10 PF05878.11 OAG42463.1 - 0.11 11.7 0.1 0.15 11.2 0.1 1.1 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns9/Pns10 ThiF PF00899.21 OAG42464.1 - 1e-117 391.8 0.0 1.7e-76 256.8 0.0 2.4 2 1 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 OAG42464.1 - 2.6e-90 302.8 0.9 4.2e-90 302.1 0.1 1.9 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site E1_UFD PF09358.10 OAG42464.1 - 1.7e-30 105.6 0.1 4.1e-30 104.3 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin fold domain E1_FCCH PF16190.5 OAG42464.1 - 6.4e-29 100.0 0.0 1.8e-28 98.6 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_4HB PF16191.5 OAG42464.1 - 7.3e-26 90.2 2.3 9.1e-26 89.8 0.7 2.1 2 0 0 2 2 2 1 Ubiquitin-activating enzyme E1 four-helix bundle Rtt106_N PF18215.1 OAG42464.1 - 0.082 12.7 0.0 0.27 11.0 0.0 1.9 1 0 0 1 1 1 0 Histone chaperone Rtt106 N-terminal domain NAD_binding_7 PF13241.6 OAG42464.1 - 0.11 13.0 0.1 0.99 9.9 0.0 2.6 3 0 0 3 3 3 0 Putative NAD(P)-binding GCP_C_terminal PF04130.13 OAG42465.1 - 1.1e-21 77.6 0.3 1.7e-21 77.0 0.3 1.2 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 OAG42465.1 - 3.5e-21 76.1 0.0 5.9e-21 75.4 0.0 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal Sulfotransfer_4 PF17784.1 OAG42466.1 - 2.5e-49 168.0 0.0 3.1e-49 167.7 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OAG42466.1 - 2e-07 31.6 0.2 0.00037 20.9 0.0 2.3 1 1 0 2 2 2 2 Sulfotransferase family adh_short_C2 PF13561.6 OAG42467.1 - 1.1e-47 162.5 0.4 1.4e-47 162.2 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG42467.1 - 6e-41 140.1 0.3 8.7e-41 139.5 0.1 1.3 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 OAG42467.1 - 1.1e-11 44.9 0.1 2.1e-11 44.1 0.1 1.4 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OAG42467.1 - 0.02 14.0 0.0 0.027 13.6 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 OAG42467.1 - 0.074 12.4 0.1 1.1 8.6 0.0 2.3 2 1 0 2 2 2 0 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 OAG42467.1 - 0.14 11.6 0.2 0.4 10.1 0.2 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family FMO-like PF00743.19 OAG42468.1 - 1.4e-14 53.4 0.6 9.5e-13 47.4 0.2 2.9 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OAG42468.1 - 4e-11 43.0 0.0 9.1e-11 41.8 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 OAG42468.1 - 6e-06 25.7 0.0 7.7e-05 22.1 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG42468.1 - 4.5e-05 22.8 0.0 0.00073 18.8 0.0 2.7 4 0 0 4 4 4 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 OAG42468.1 - 0.016 14.4 0.2 2.3 7.4 0.1 2.8 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OAG42468.1 - 0.19 10.8 0.0 5.3 6.0 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A Sugar_tr PF00083.24 OAG42469.1 - 1.4e-68 231.9 20.7 1.7e-68 231.6 20.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG42469.1 - 6.8e-23 81.2 30.3 6.8e-23 81.2 30.3 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily adh_short PF00106.25 OAG42470.1 - 7.3e-62 208.3 2.8 3.5e-39 134.3 1.1 2.3 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAG42470.1 - 1.5e-53 181.7 0.1 3.9e-32 111.7 0.1 2.4 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase MaoC_dehydratas PF01575.19 OAG42470.1 - 2.3e-28 98.2 0.0 5.4e-28 97.0 0.0 1.6 1 0 0 1 1 1 1 MaoC like domain KR PF08659.10 OAG42470.1 - 6.5e-11 42.5 2.8 1.1e-10 41.8 0.6 2.2 2 0 0 2 2 2 1 KR domain MaoC_dehydrat_N PF13452.6 OAG42470.1 - 1.6e-06 28.3 0.0 0.00012 22.2 0.0 2.4 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase THF_DHG_CYH_C PF02882.19 OAG42470.1 - 0.011 15.0 0.3 0.29 10.4 0.0 2.6 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Glu_dehyd_C PF16912.5 OAG42470.1 - 0.1 12.1 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus 3HCDH_N PF02737.18 OAG42470.1 - 0.27 11.1 3.7 5.8 6.8 0.6 2.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AMP-binding PF00501.28 OAG42471.1 - 5e-83 279.0 0.0 5.9e-83 278.8 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG42471.1 - 1.3e-12 48.5 0.1 1.9e-11 44.8 0.0 2.3 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Pyr_redox_2 PF07992.14 OAG42472.1 - 1.8e-13 50.4 0.0 4.8e-12 45.7 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG42472.1 - 1.3e-10 41.1 0.0 2.6e-09 36.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG42472.1 - 9.4e-10 38.1 0.1 2e-07 30.5 0.0 2.3 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 OAG42472.1 - 1.3e-08 35.0 0.0 2.1e-07 31.1 0.1 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAG42472.1 - 6.4e-05 22.7 1.7 0.36 10.4 0.1 3.4 3 1 1 4 4 4 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 OAG42472.1 - 0.00021 21.3 2.7 0.49 10.4 0.8 4.1 3 1 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 OAG42472.1 - 0.0045 17.5 0.1 2 9.1 0.1 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAG42472.1 - 0.0077 15.4 0.0 0.013 14.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_7 PF13241.6 OAG42472.1 - 0.0078 16.6 0.0 1.2 9.6 0.0 3.2 3 0 0 3 3 3 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 OAG42472.1 - 0.015 15.3 0.2 0.17 11.9 0.0 2.5 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.14 OAG42472.1 - 0.027 13.2 0.4 0.98 8.0 0.1 2.6 2 0 0 2 2 2 0 HI0933-like protein FAD_oxidored PF12831.7 OAG42472.1 - 0.033 13.6 0.0 0.069 12.5 0.0 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.19 OAG42472.1 - 0.04 13.3 0.0 0.082 12.3 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ThiF PF00899.21 OAG42472.1 - 0.053 12.9 0.0 0.22 10.8 0.0 2.0 2 0 0 2 2 2 0 ThiF family Thi4 PF01946.17 OAG42472.1 - 0.082 12.1 0.1 0.68 9.1 0.0 2.2 3 0 0 3 3 3 0 Thi4 family DUF987 PF06174.11 OAG42472.1 - 0.14 12.1 0.0 0.34 10.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF987) Fungal_trans PF04082.18 OAG42473.1 - 0.0038 16.3 1.1 0.33 9.9 0.1 2.5 1 1 0 2 2 2 2 Fungal specific transcription factor domain APH PF01636.23 OAG42474.1 - 1.4e-44 152.8 0.0 2.4e-44 152.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 OAG42474.1 - 3.2e-06 26.7 0.0 7e-06 25.6 0.0 1.4 2 0 0 2 2 2 1 Ecdysteroid kinase RIO1 PF01163.22 OAG42474.1 - 3.1e-05 23.6 0.0 0.035 13.7 0.0 2.3 2 0 0 2 2 2 2 RIO1 family DUF1679 PF07914.11 OAG42474.1 - 4.8e-05 22.4 0.0 0.018 13.9 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1679) Choline_kinase PF01633.20 OAG42474.1 - 0.00053 19.6 0.0 0.001 18.7 0.0 1.4 2 0 0 2 2 2 1 Choline/ethanolamine kinase Fructosamin_kin PF03881.14 OAG42474.1 - 0.0007 18.9 0.0 0.0014 17.9 0.0 1.3 1 1 0 1 1 1 1 Fructosamine kinase Acyl-CoA_dh_1 PF00441.24 OAG42475.1 - 5.1e-28 98.2 0.6 8.8e-28 97.4 0.6 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 OAG42475.1 - 2.8e-15 56.3 0.0 5e-15 55.5 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 OAG42475.1 - 2.1e-12 47.7 0.0 4.7e-12 46.6 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 OAG42475.1 - 4.2e-10 40.0 0.3 8.7e-10 39.0 0.3 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain AAA_assoc_C PF09821.9 OAG42475.1 - 0.16 12.5 0.2 3.7 8.1 0.0 2.3 2 0 0 2 2 2 0 C-terminal AAA-associated domain 4HBT PF03061.22 OAG42476.1 - 1.1e-09 38.5 0.0 2.5e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 Thioesterase superfamily PS-DH PF14765.6 OAG42476.1 - 0.19 10.9 0.0 0.34 10.1 0.0 1.4 2 0 0 2 2 2 0 Polyketide synthase dehydratase Fungal_trans PF04082.18 OAG42477.1 - 3.7e-28 98.3 0.3 7e-28 97.4 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain AMP-binding PF00501.28 OAG42478.1 - 5.3e-73 246.0 0.0 7.3e-73 245.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Mito_carr PF00153.27 OAG42478.1 - 2e-46 155.8 0.5 7.1e-16 57.9 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein AMP-binding_C PF13193.6 OAG42478.1 - 1.7e-12 48.1 0.1 2e-11 44.7 0.0 2.4 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Aldedh PF00171.22 OAG42479.1 - 1.5e-150 501.7 0.0 1.7e-150 501.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Borrelia_P13 PF05628.12 OAG42479.1 - 0.12 12.3 0.0 0.31 11.0 0.0 1.7 1 0 0 1 1 1 0 Borrelia membrane protein P13 Lactamase_B PF00753.27 OAG42480.1 - 5.5e-07 29.8 1.1 1e-06 28.9 1.1 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OAG42480.1 - 0.019 14.5 0.0 0.035 13.6 0.0 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain RNase_PH PF01138.21 OAG42481.1 - 4.3e-25 88.7 0.0 1.2e-24 87.3 0.0 1.7 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 CHZ PF09649.10 OAG42482.1 - 0.89 9.1 4.5 1.8 8.1 0.4 2.7 2 0 0 2 2 2 0 Histone chaperone domain CHZ Peptidase_S10 PF00450.22 OAG42484.1 - 5.7e-113 378.5 0.0 8.4e-113 377.9 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase MHYT PF03707.16 OAG42484.1 - 7.6e-17 61.2 14.9 4.3e-09 36.4 0.4 4.1 4 0 0 4 4 4 3 Bacterial signalling protein N terminal repeat Hydrolase_4 PF12146.8 OAG42484.1 - 0.095 11.9 0.0 1.6 8.0 0.0 2.4 2 0 0 2 2 2 0 Serine aminopeptidase, S33 ATP_bind_1 PF03029.17 OAG42485.1 - 3.8e-71 239.7 0.0 5.6e-71 239.1 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein MeaB PF03308.16 OAG42485.1 - 0.0026 16.8 0.1 0.0068 15.4 0.0 1.6 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 OAG42485.1 - 0.013 15.6 0.0 0.12 12.4 0.0 2.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase RNA_helicase PF00910.22 OAG42485.1 - 0.043 14.2 0.0 0.076 13.4 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 OAG42485.1 - 0.043 14.4 1.2 0.053 14.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_31 PF13614.6 OAG42485.1 - 0.053 13.4 0.0 8.6 6.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.7 OAG42485.1 - 0.076 11.9 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_30 PF13604.6 OAG42485.1 - 0.092 12.5 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 OAG42485.1 - 0.18 12.2 0.2 0.18 12.2 0.2 2.2 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.6 OAG42485.1 - 0.65 10.2 0.0 0.65 10.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain RNase_P_Rpp14 PF01900.19 OAG42486.1 - 1.4e-30 105.6 0.0 1.9e-30 105.2 0.0 1.2 1 0 0 1 1 1 1 Rpp14/Pop5 family RSN1_7TM PF02714.15 OAG42488.1 - 4.1e-84 282.1 25.2 4.1e-84 282.1 25.2 2.8 3 0 0 3 3 3 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 OAG42488.1 - 4.8e-47 159.6 1.3 4.8e-47 159.6 1.3 3.3 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 OAG42488.1 - 2.2e-37 129.0 0.4 3.3e-37 128.4 0.4 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 OAG42488.1 - 2.8e-28 97.9 0.1 1.1e-27 96.0 0.0 2.0 2 0 0 2 2 2 1 Extracellular tail, of 10TM putative phosphate transporter DUF3925 PF13063.6 OAG42488.1 - 1.9 8.8 8.5 1.6 9.0 0.5 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3925) Nop53 PF07767.11 OAG42489.1 - 1.2e-87 295.0 24.4 1.4e-87 294.7 24.4 1.1 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) Repressor_Mnt PF11423.8 OAG42489.1 - 0.48 10.2 2.4 1 9.2 2.4 1.6 1 0 0 1 1 1 0 Regulatory protein Mnt 4HBT PF03061.22 OAG42490.1 - 3.5e-11 43.3 0.1 6.7e-11 42.4 0.1 1.5 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.6 OAG42490.1 - 0.023 14.9 0.2 0.039 14.1 0.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4442) Abhydrolase_3 PF07859.13 OAG42491.1 - 2.7e-32 112.3 0.0 3.9e-32 111.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 OAG42491.1 - 4.4e-11 42.3 0.0 6.6e-11 41.7 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase GST_N_3 PF13417.6 OAG42491.1 - 7.1e-10 39.2 0.1 2.3e-09 37.5 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAG42491.1 - 1.2e-05 25.3 0.1 2.6e-05 24.1 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 OAG42491.1 - 0.00016 21.9 0.0 0.00044 20.5 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Abhydrolase_2 PF02230.16 OAG42491.1 - 0.095 12.5 0.0 0.33 10.7 0.0 1.9 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 OAG42491.1 - 0.19 11.2 0.0 0.51 9.8 0.0 1.6 2 0 0 2 2 2 0 Prolyl oligopeptidase family AMP-binding PF00501.28 OAG42492.1 - 2.3e-84 283.5 0.0 3.5e-84 282.8 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG42492.1 - 7.9e-16 58.8 0.0 1.7e-14 54.5 0.0 2.5 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain GST_N PF02798.20 OAG42493.1 - 3.9e-09 36.7 0.0 1e-08 35.4 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OAG42493.1 - 1.6e-08 34.6 0.0 4e-08 33.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 OAG42493.1 - 3.6e-07 30.5 0.0 7.1e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OAG42493.1 - 1.2e-06 28.8 0.0 2e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAG42493.1 - 1.4e-05 25.0 0.1 3.4e-05 23.8 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OAG42493.1 - 0.00079 19.6 0.0 0.0016 18.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glyco_hydro_39 PF01229.17 OAG42494.1 - 4.5e-43 147.6 0.0 9.4e-43 146.5 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 39 Fungal_trans PF04082.18 OAG42495.1 - 1.5e-06 27.5 0.3 4.8e-06 25.8 0.3 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 OAG42496.1 - 3.3e-24 85.5 27.0 3.1e-21 75.7 7.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 OAG42496.1 - 0.0009 18.6 0.8 0.0009 18.6 0.8 2.0 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB EamA PF00892.20 OAG42496.1 - 0.046 13.9 0.3 0.046 13.9 0.3 3.2 3 1 1 4 4 4 0 EamA-like transporter family Zn_clus PF00172.18 OAG42497.1 - 9.5e-07 28.8 6.9 1.6e-06 28.1 6.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAG42497.1 - 1.7e-05 24.0 0.0 4.9e-05 22.5 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF4387 PF14330.6 OAG42498.1 - 5.7e-35 119.9 0.0 1.1e-34 119.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4387) AtuA PF07287.11 OAG42498.1 - 2.1e-21 76.0 0.0 1.6e-20 73.2 0.0 1.9 1 1 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA Sugar_tr PF00083.24 OAG42499.1 - 3.9e-75 253.5 21.1 4.9e-75 253.1 21.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Lactonase PF10282.9 OAG42499.1 - 5.5e-62 210.0 0.1 7.7e-62 209.5 0.1 1.1 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller MFS_1 PF07690.16 OAG42499.1 - 3.9e-22 78.7 17.1 3.9e-22 78.7 17.1 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily PD40 PF07676.12 OAG42499.1 - 0.062 13.3 0.0 2.4 8.2 0.0 2.8 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat DUF3611 PF12263.8 OAG42499.1 - 1.8 8.5 8.9 3.1 7.7 0.2 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3611) Myb_Cef PF11831.8 OAG42500.1 - 1.4e-48 165.5 11.4 1.4e-48 165.5 11.4 3.7 5 0 0 5 5 5 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.31 OAG42500.1 - 1.6e-21 76.2 4.7 3.3e-10 40.0 0.8 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OAG42500.1 - 1.6e-20 73.1 4.9 1.6e-13 50.7 1.5 2.7 1 1 1 2 2 2 2 Myb-like DNA-binding domain Rap1_C PF11626.8 OAG42500.1 - 0.0068 16.5 0.3 0.14 12.3 0.0 2.9 2 0 0 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain DUF848 PF05852.11 OAG42500.1 - 0.02 15.0 2.5 0.02 15.0 2.5 2.3 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) tRNA-synt_2b PF00587.25 OAG42502.1 - 4e-33 114.9 0.0 5.9e-33 114.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 OAG42502.1 - 2.3e-12 46.9 0.1 4.6e-12 45.9 0.1 1.5 1 0 0 1 1 1 1 Anticodon binding domain Prefoldin PF02996.17 OAG42503.1 - 2.8e-18 66.0 0.0 4e-18 65.5 0.0 1.3 1 0 0 1 1 1 1 Prefoldin subunit Snapin_Pallidin PF14712.6 OAG42503.1 - 0.045 14.2 1.7 0.34 11.3 0.8 2.1 2 0 0 2 2 2 0 Snapin/Pallidin Dynamitin PF04912.14 OAG42503.1 - 0.08 12.3 1.0 0.39 10.0 1.0 1.9 1 1 0 1 1 1 0 Dynamitin DUF1192 PF06698.11 OAG42503.1 - 0.08 13.0 0.2 0.08 13.0 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Prefoldin_2 PF01920.20 OAG42503.1 - 0.089 12.8 0.3 5 7.1 0.1 2.1 2 0 0 2 2 2 0 Prefoldin subunit CC2-LZ PF16516.5 OAG42503.1 - 0.16 12.3 0.8 4.2 7.8 0.2 2.1 2 0 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator IFT57 PF10498.9 OAG42503.1 - 0.18 10.8 0.3 0.49 9.3 0.0 1.6 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 KH_1 PF00013.29 OAG42504.1 - 0.00039 20.2 0.0 0.078 12.8 0.0 2.5 2 0 0 2 2 2 2 KH domain AAA PF00004.29 OAG42505.1 - 6.2e-16 59.0 0.0 1.2e-15 58.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_10 PF17872.1 OAG42505.1 - 2.7e-12 46.7 0.2 7.6e-12 45.2 0.2 1.7 1 0 0 1 1 1 1 AAA lid domain AAA_16 PF13191.6 OAG42505.1 - 1.8e-10 41.4 0.0 1.2e-09 38.8 0.0 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OAG42505.1 - 1.2e-09 38.5 0.0 3.7e-09 37.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain BAH PF01426.18 OAG42505.1 - 5.2e-05 23.1 0.0 0.00015 21.6 0.0 1.8 1 0 0 1 1 1 1 BAH domain AAA_19 PF13245.6 OAG42505.1 - 0.0031 17.8 0.0 0.0086 16.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain PIF1 PF05970.14 OAG42505.1 - 0.028 13.6 0.0 0.046 12.9 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase AAA_11 PF13086.6 OAG42505.1 - 0.033 14.0 2.0 0.05 13.4 0.0 2.2 3 0 0 3 3 3 0 AAA domain AAA_28 PF13521.6 OAG42505.1 - 0.037 14.3 0.0 0.11 12.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 OAG42505.1 - 0.065 12.5 0.0 0.13 11.5 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_18 PF13238.6 OAG42505.1 - 0.078 13.5 0.0 0.18 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 OAG42505.1 - 0.13 12.2 0.0 0.42 10.5 0.0 1.9 2 1 0 2 2 2 0 NACHT domain ADH_N PF08240.12 OAG42506.1 - 5.8e-29 100.2 2.9 1.2e-28 99.2 2.9 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG42506.1 - 6.8e-20 71.4 0.0 1.1e-19 70.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 OAG42506.1 - 3.6e-08 33.1 0.5 1.2e-07 31.4 0.5 1.8 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 OAG42506.1 - 0.00067 19.0 0.2 0.0012 18.2 0.2 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.6 OAG42506.1 - 0.0085 17.1 0.0 0.017 16.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 OAG42506.1 - 0.12 12.3 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-associated MFS_1 PF07690.16 OAG42507.1 - 2.6e-27 95.7 31.7 2.7e-27 95.6 28.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily PGA_cap PF09587.10 OAG42508.1 - 4.5e-47 160.7 0.0 1.3e-46 159.1 0.0 1.7 1 1 0 1 1 1 1 Bacterial capsule synthesis protein PGA_cap Abhydrolase_6 PF12697.7 OAG42509.1 - 1.5e-10 42.0 16.7 1.8e-09 38.5 16.7 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAG42509.1 - 0.00087 19.0 0.0 0.002 17.8 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Fungal_trans_2 PF11951.8 OAG42511.1 - 0.00075 18.4 0.3 0.002 17.0 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain VPDSG-CTERM PF18205.1 OAG42512.1 - 0.16 11.8 2.0 0.54 10.1 2.0 2.0 1 0 0 1 1 1 0 VPDSG-CTERM motif CBF PF03914.17 OAG42513.1 - 3.9e-50 170.2 0.3 3.9e-50 170.2 0.3 2.4 2 0 0 2 2 2 1 CBF/Mak21 family Aa_trans PF01490.18 OAG42514.1 - 8.2e-23 80.8 36.0 1.7e-22 79.7 36.0 1.4 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein SnoaL_2 PF12680.7 OAG42515.1 - 3.2e-09 37.3 0.0 4.3e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 OAG42515.1 - 0.0037 17.1 0.1 0.0065 16.3 0.1 1.5 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_4 PF13577.6 OAG42515.1 - 0.0098 16.0 0.1 0.014 15.5 0.1 1.2 1 0 0 1 1 1 1 SnoaL-like domain TIMP PF00965.17 OAG42515.1 - 0.016 15.0 0.0 0.019 14.8 0.0 1.2 1 0 0 1 1 1 0 Tissue inhibitor of metalloproteinase DUF4440 PF14534.6 OAG42515.1 - 0.02 15.3 0.0 0.029 14.8 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4440) Anp1 PF03452.14 OAG42516.1 - 5e-114 380.2 0.0 2.2e-113 378.0 0.0 1.8 2 0 0 2 2 2 1 Anp1 Glyco_tranf_2_4 PF13704.6 OAG42516.1 - 0.0092 16.5 0.1 0.025 15.1 0.1 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 2 Rad54_N PF08658.10 OAG42516.1 - 0.06 13.5 0.8 0.12 12.6 0.8 1.4 1 0 0 1 1 1 0 Rad54 N terminal Ferlin_C PF16165.5 OAG42516.1 - 1.1 9.2 3.1 2.1 8.3 3.1 1.4 1 0 0 1 1 1 0 Ferlin C-terminus DUF2098 PF09871.9 OAG42516.1 - 1.1 9.7 5.0 2.3 8.6 5.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2098) Dcc1 PF09724.9 OAG42517.1 - 1.5e-13 50.8 0.0 6.4e-13 48.7 0.0 2.0 1 1 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 Fe-ADH PF00465.19 OAG42518.1 - 2.5e-62 210.8 0.1 3.1e-62 210.5 0.1 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 OAG42518.1 - 1.6e-10 41.2 0.0 2.1e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase DUF3748 PF12566.8 OAG42518.1 - 0.17 11.9 0.0 0.39 10.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3748) Aldo_ket_red PF00248.21 OAG42521.1 - 3.4e-42 144.6 0.0 1e-40 139.8 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family T4BSS_DotH_IcmK PF12293.8 OAG42521.1 - 0.051 12.8 0.0 0.16 11.2 0.0 1.8 2 0 0 2 2 2 0 Putative outer membrane core complex of type IVb secretion Ras PF00071.22 OAG42522.1 - 7.8e-39 132.9 0.1 9.7e-39 132.6 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAG42522.1 - 9.6e-18 64.5 0.0 1.5e-17 63.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAG42522.1 - 1.1e-09 38.0 0.1 1.4e-09 37.6 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OAG42522.1 - 1.8e-07 30.9 0.0 2.3e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OAG42522.1 - 0.00025 20.5 0.0 0.0003 20.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Choline_transpo PF04515.12 OAG42523.1 - 3.3e-26 92.3 15.2 3.3e-26 92.3 15.2 2.3 2 1 0 2 2 2 1 Plasma-membrane choline transporter PMT PF02366.18 OAG42524.1 - 2e-88 296.1 17.3 2e-88 296.1 17.3 1.9 2 1 1 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 OAG42524.1 - 3.1e-65 219.5 15.0 3.1e-65 219.5 15.0 2.6 2 1 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 OAG42524.1 - 1.1e-33 116.6 0.2 1.8e-33 115.9 0.2 1.2 1 0 0 1 1 1 1 MIR domain Fungal_trans PF04082.18 OAG42525.1 - 6.7e-09 35.2 0.5 1.2e-08 34.3 0.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG42525.1 - 7.6e-06 25.9 13.7 1.3e-05 25.2 13.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DAO PF01266.24 OAG42526.1 - 5.4e-24 85.4 10.2 5e-15 55.9 0.9 2.9 2 2 0 2 2 2 2 FAD dependent oxidoreductase CAP_N PF01213.19 OAG42526.1 - 0.56 9.6 3.4 1.1 8.7 3.4 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal CAF1A PF12253.8 OAG42527.1 - 2.3e-18 66.1 5.9 2.3e-18 66.1 5.9 3.5 2 1 1 3 3 1 1 Chromatin assembly factor 1 subunit A DDHD PF02862.17 OAG42527.1 - 0.12 12.5 1.9 0.24 11.5 1.9 1.5 1 0 0 1 1 1 0 DDHD domain DUF4407 PF14362.6 OAG42527.1 - 0.12 11.7 11.6 0.19 11.1 11.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RR_TM4-6 PF06459.12 OAG42527.1 - 0.24 11.2 22.9 0.029 14.2 17.8 1.9 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Zip PF02535.22 OAG42527.1 - 0.9 8.7 2.2 1.4 8.1 2.2 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Hamartin PF04388.12 OAG42527.1 - 4.9 5.7 15.8 0.52 8.9 11.1 1.6 2 0 0 2 2 2 0 Hamartin protein DUF3450 PF11932.8 OAG42527.1 - 4.9 6.4 14.8 8.2 5.6 14.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF966 PF06136.13 OAG42527.1 - 5.1 6.7 13.9 9.7 5.8 13.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF966) FYDLN_acid PF09538.10 OAG42527.1 - 5.2 7.8 35.7 0.051 14.3 10.1 3.5 2 1 1 3 3 2 0 Protein of unknown function (FYDLN_acid) DUF2151 PF10221.9 OAG42527.1 - 5.4 5.5 11.2 7.7 5.0 11.2 1.2 1 0 0 1 1 1 0 Cell cycle and development regulator Presenilin PF01080.17 OAG42527.1 - 8.5 5.0 16.9 14 4.3 16.9 1.3 1 0 0 1 1 1 0 Presenilin Ank_2 PF12796.7 OAG42529.1 - 2.3e-26 92.2 0.0 1.8e-11 44.5 0.0 3.8 1 1 4 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.30 OAG42529.1 - 1.3e-13 50.7 0.1 0.0023 18.3 0.0 5.1 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 OAG42529.1 - 2.1e-13 50.2 0.1 0.0011 19.3 0.0 4.6 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG42529.1 - 7.8e-13 47.4 0.1 0.0016 18.8 0.0 6.1 5 1 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.6 OAG42529.1 - 1.6e-12 47.6 0.1 0.009 16.6 0.0 4.8 3 1 1 4 4 4 3 Ankyrin repeats (many copies) TPR_12 PF13424.6 OAG42529.1 - 5.9e-09 36.1 5.2 0.00039 20.7 0.4 4.0 3 2 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 OAG42529.1 - 2e-08 33.7 1.6 0.016 15.3 0.2 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 OAG42529.1 - 1e-06 29.1 0.2 0.00012 22.5 0.1 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 OAG42529.1 - 5e-06 26.2 0.3 1.8 8.8 0.1 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 OAG42529.1 - 2.8e-05 23.7 0.3 0.88 9.5 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 OAG42529.1 - 0.00024 21.1 0.1 2.2 8.7 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 OAG42529.1 - 0.00039 20.2 0.1 7.9 6.5 0.0 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 OAG42529.1 - 0.0061 17.2 3.6 0.089 13.5 0.2 4.0 4 0 0 4 4 3 1 Tetratricopeptide repeat Helo_like_N PF17111.5 OAG42529.1 - 0.017 14.5 0.1 0.07 12.5 0.0 2.0 1 1 1 2 2 2 0 Fungal N-terminal domain of STAND proteins TPR_14 PF13428.6 OAG42529.1 - 0.021 15.6 5.2 19 6.4 0.0 5.1 5 0 0 5 5 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 OAG42529.1 - 0.038 14.2 0.1 1.4 9.2 0.0 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Methyltransf_9 PF08003.11 OAG42529.1 - 0.053 12.4 0.1 3.9 6.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) Img2 PF05046.14 OAG42529.1 - 0.092 13.1 0.1 6.4 7.2 0.1 2.7 2 1 1 3 3 3 0 Mitochondrial large subunit ribosomal protein (Img2) TPR_4 PF07721.14 OAG42529.1 - 0.17 12.6 0.8 16 6.5 0.0 4.1 4 0 0 4 4 3 0 Tetratricopeptide repeat Fungal_trans PF04082.18 OAG42530.1 - 6.3e-19 68.0 0.1 9.6e-19 67.4 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ribosomal_L27 PF01016.19 OAG42531.1 - 4.6e-13 49.0 1.8 6.3e-13 48.5 0.0 2.1 2 1 0 2 2 2 1 Ribosomal L27 protein TPR_1 PF00515.28 OAG42532.1 - 4.3e-07 29.5 0.0 0.56 10.1 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 OAG42532.1 - 2.5e-06 27.2 0.1 0.12 12.5 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat UBA PF00627.31 OAG42532.1 - 2e-05 24.4 0.0 4.5e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain TPR_12 PF13424.6 OAG42532.1 - 0.0037 17.5 0.4 0.039 14.2 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat DnaJ PF00226.31 OAG42532.1 - 0.14 12.3 0.0 0.38 10.9 0.0 1.7 1 0 0 1 1 1 0 DnaJ domain DUF1688 PF07958.11 OAG42534.1 - 4e-184 612.2 0.0 4.5e-184 612.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) Gtr1_RagA PF04670.12 OAG42535.1 - 9.8e-93 309.8 0.5 1.2e-92 309.5 0.5 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 OAG42535.1 - 2.7e-10 40.5 0.0 5.4e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 OAG42535.1 - 5.9e-10 39.0 0.0 1.1e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 OAG42535.1 - 4.7e-08 33.1 0.0 8.7e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 OAG42535.1 - 1.1e-07 31.4 0.0 1.7e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1_Xtn PF16897.5 OAG42535.1 - 0.00023 21.1 0.3 0.0025 17.8 0.1 2.2 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain GTP_EFTU PF00009.27 OAG42535.1 - 0.0013 18.3 0.0 0.002 17.7 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain G-alpha PF00503.20 OAG42535.1 - 0.0058 15.8 3.5 1.3 8.1 1.2 2.7 2 1 1 3 3 3 2 G-protein alpha subunit ABC_tran PF00005.27 OAG42535.1 - 0.0084 16.6 0.6 0.018 15.5 0.2 1.8 2 1 0 2 2 2 1 ABC transporter AIG1 PF04548.16 OAG42535.1 - 0.019 14.3 1.4 0.06 12.7 0.3 2.3 2 1 0 2 2 2 0 AIG1 family DUF815 PF05673.13 OAG42535.1 - 0.019 14.1 0.1 0.045 12.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_29 PF13555.6 OAG42535.1 - 0.021 14.6 0.7 0.052 13.3 0.3 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain SRPRB PF09439.10 OAG42535.1 - 0.024 14.1 0.0 0.035 13.5 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 OAG42535.1 - 0.024 14.5 1.9 0.31 10.9 0.0 2.9 3 1 1 4 4 4 0 RsgA GTPase AAA_7 PF12775.7 OAG42535.1 - 0.06 12.9 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Zn_clus PF00172.18 OAG42536.1 - 1.4e-05 25.1 10.5 2.6e-05 24.2 10.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DIOX_N PF14226.6 OAG42537.1 - 3.6e-20 72.9 0.1 1.9e-19 70.5 0.0 2.1 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OAG42537.1 - 3.5e-17 62.7 0.0 5.9e-17 62.0 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily POTRA PF07244.15 OAG42537.1 - 0.029 14.9 0.1 0.81 10.3 0.1 2.3 2 0 0 2 2 2 0 Surface antigen variable number repeat DUF5401 PF17380.2 OAG42537.1 - 0.26 9.3 3.9 0.36 8.9 3.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) Cupin_2 PF07883.11 OAG42538.1 - 2.3e-10 40.0 0.0 3.9e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 OAG42538.1 - 0.055 13.2 0.1 0.093 12.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Apolipoprotein PF01442.18 OAG42539.1 - 0.0074 16.2 2.1 0.012 15.5 2.1 1.4 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain ApoO PF09769.9 OAG42539.1 - 0.032 14.2 5.0 1.6 8.7 0.2 2.2 1 1 1 2 2 2 0 Apolipoprotein O CHDCT2 PF08074.11 OAG42539.1 - 0.19 11.9 1.5 0.25 11.5 1.5 1.4 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain ApoLp-III PF07464.11 OAG42539.1 - 1.3 9.1 8.8 0.46 10.6 4.6 2.0 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) CoA_transf_3 PF02515.17 OAG42541.1 - 2.5e-66 224.3 0.0 2.1e-65 221.2 0.0 1.9 1 1 0 1 1 1 1 CoA-transferase family III DUF2401 PF10287.9 OAG42543.1 - 0.00067 19.3 0.0 0.001 18.7 0.0 1.3 1 0 0 1 1 1 1 Putative TOS1-like glycosyl hydrolase (DUF2401) PIG-H PF10181.9 OAG42545.1 - 0.061 13.2 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 GPI-GlcNAc transferase complex, PIG-H component IPP-2 PF04979.14 OAG42546.1 - 1.3e-19 71.3 15.6 1.3e-19 71.3 15.6 2.0 2 1 0 2 2 2 1 Protein phosphatase inhibitor 2 (IPP-2) Tudor_3 PF18115.1 OAG42547.1 - 7.2e-19 67.4 0.0 2e-18 65.9 0.0 1.9 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain Rad9_Rad53_bind PF08605.10 OAG42547.1 - 4.6e-17 62.4 0.0 8.3e-17 61.6 0.0 1.4 1 0 0 1 1 1 1 Fungal Rad9-like Rad53-binding BRCT PF00533.26 OAG42547.1 - 0.00015 22.1 0.0 0.00031 21.1 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 OAG42547.1 - 0.0018 18.7 0.0 0.01 16.3 0.0 2.3 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain Adeno_E3_CR2 PF02439.15 OAG42547.1 - 0.013 15.3 0.8 0.027 14.2 0.8 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Syndecan PF01034.20 OAG42547.1 - 0.022 14.7 0.0 0.043 13.7 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain Thiolase_N PF00108.23 OAG42547.1 - 0.031 13.6 0.0 0.052 12.9 0.0 1.3 1 0 0 1 1 1 0 Thiolase, N-terminal domain RTT107_BRCT_5 PF16770.5 OAG42547.1 - 0.049 13.5 0.0 0.16 11.8 0.0 1.9 2 0 0 2 2 2 0 Regulator of Ty1 transposition protein 107 BRCT domain Fungal_trans PF04082.18 OAG42549.1 - 3.8e-07 29.4 0.9 2.1e-06 26.9 0.3 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain TNF PF00229.18 OAG42549.1 - 0.035 14.1 0.0 0.43 10.5 0.0 2.2 2 0 0 2 2 2 0 TNF(Tumour Necrosis Factor) family 7kD_DNA_binding PF02294.18 OAG42549.1 - 0.19 11.8 0.0 0.35 10.9 0.0 1.4 1 0 0 1 1 1 0 7kD DNA-binding domain tRNA_int_endo PF01974.17 OAG42551.1 - 8.3e-19 67.5 0.0 2.1e-18 66.2 0.0 1.6 1 1 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.14 OAG42551.1 - 2.9e-06 26.8 0.0 0.0015 18.2 0.0 2.4 2 0 0 2 2 2 2 tRNA intron endonuclease, N-terminal domain U79_P34 PF03064.16 OAG42551.1 - 0.025 14.0 1.3 0.058 12.7 1.3 1.6 1 0 0 1 1 1 0 HSV U79 / HCMV P34 NOB1_Zn_bind PF08772.11 OAG42552.1 - 4.6e-31 106.8 3.5 7.8e-31 106.1 3.5 1.4 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like PIN_6 PF17146.4 OAG42552.1 - 2.5e-27 95.2 0.0 1.9e-26 92.4 0.0 2.5 3 0 0 3 3 3 1 PIN domain of ribonuclease zf-NADH-PPase PF09297.11 OAG42552.1 - 0.015 14.9 3.0 0.027 14.1 1.0 2.2 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain HypA PF01155.19 OAG42552.1 - 0.072 13.1 1.3 0.18 11.8 1.3 1.6 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc-ribbons_6 PF07191.12 OAG42552.1 - 0.13 12.3 4.1 0.23 11.5 4.1 1.3 1 0 0 1 1 1 0 zinc-ribbons Zn-ribbon_8 PF09723.10 OAG42552.1 - 0.88 9.7 4.2 0.35 11.0 1.3 1.9 2 0 0 2 2 2 0 Zinc ribbon domain MFS_1 PF07690.16 OAG42553.1 - 6.7e-22 77.9 34.4 3.3e-20 72.3 32.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_16 PF00722.21 OAG42554.1 - 8.4e-07 28.6 0.0 8.4e-07 28.6 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 POT1 PF02765.17 OAG42555.1 - 1.1e-11 44.8 0.0 1.9e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 eIF-3c_N PF05470.12 OAG42555.1 - 0.34 9.2 3.3 0.9 7.8 3.3 1.6 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Sdh_cyt PF01127.22 OAG42556.1 - 2.1e-21 76.2 6.9 2.9e-21 75.7 6.9 1.2 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Phosphoesterase PF04185.14 OAG42559.1 - 6e-58 196.7 7.8 1.6e-57 195.3 7.8 1.6 1 1 0 1 1 1 1 Phosphoesterase family VIT1 PF01988.19 OAG42560.1 - 5.5e-67 225.8 1.6 6.5e-67 225.5 1.6 1.0 1 0 0 1 1 1 1 VIT family DUF1146 PF06612.11 OAG42560.1 - 0.082 13.0 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1146) MFS_1 PF07690.16 OAG42561.1 - 1.4e-30 106.4 34.2 1.4e-30 106.4 34.2 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 OAG42561.1 - 2.2 6.5 11.1 0.67 8.2 6.0 2.5 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family AMP-binding PF00501.28 OAG42562.1 - 1.5e-62 211.6 0.0 2e-62 211.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG42562.1 - 8.9e-12 45.8 0.0 2.5e-11 44.4 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Fungal_trans PF04082.18 OAG42563.1 - 5.9e-15 55.0 0.0 1.3e-14 53.9 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Acetyltransf_1 PF00583.25 OAG42564.1 - 1.5e-12 47.8 0.0 2e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OAG42564.1 - 8.3e-10 38.7 0.0 1.4e-09 38.0 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OAG42564.1 - 2.4e-07 31.1 0.0 3.6e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAG42564.1 - 0.0005 20.0 0.1 0.0014 18.5 0.0 1.7 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_3 PF13302.7 OAG42564.1 - 0.0009 19.9 0.0 0.0013 19.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 OAG42564.1 - 0.0036 17.4 0.0 0.015 15.4 0.0 2.0 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 OAG42564.1 - 0.17 12.1 0.3 0.36 11.0 0.0 1.7 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase DUF4386 PF14329.6 OAG42565.1 - 0.013 15.4 5.0 0.016 15.1 5.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4386) DUF4436 PF14494.6 OAG42565.1 - 0.071 12.4 2.3 0.1 11.9 2.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4436) DUF4131 PF13567.6 OAG42565.1 - 0.085 12.5 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Presenilin PF01080.17 OAG42565.1 - 0.66 8.7 4.3 9.1 4.9 2.1 2.1 2 0 0 2 2 2 0 Presenilin DUF4834 PF16118.5 OAG42565.1 - 1.9 9.5 5.0 7.4 7.6 5.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) SPC22 PF04573.12 OAG42566.1 - 7.6e-39 132.9 0.0 2.7e-36 124.6 0.0 2.1 1 1 0 1 1 1 1 Signal peptidase subunit adh_short_C2 PF13561.6 OAG42567.1 - 2.2e-28 99.4 0.8 2.7e-28 99.1 0.8 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG42567.1 - 6.7e-20 71.4 0.4 8.8e-20 71.0 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG42567.1 - 4.6e-09 36.4 0.4 6.7e-09 35.9 0.4 1.2 1 0 0 1 1 1 1 KR domain Oxidored_nitro PF00148.19 OAG42567.1 - 0.0026 16.5 0.1 0.0044 15.8 0.1 1.3 1 1 0 1 1 1 1 Nitrogenase component 1 type Oxidoreductase Sacchrp_dh_NADP PF03435.18 OAG42567.1 - 0.046 14.0 0.3 0.076 13.3 0.3 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain THF_DHG_CYH_C PF02882.19 OAG42567.1 - 0.048 13.0 0.1 0.082 12.2 0.1 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_7 PF13241.6 OAG42567.1 - 0.062 13.7 0.2 0.1 13.1 0.2 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding DUF5641 PF18701.1 OAG42567.1 - 0.083 13.1 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5641) Eno-Rase_NADH_b PF12242.8 OAG42567.1 - 0.11 12.3 0.4 0.23 11.3 0.4 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase TFIIA PF03153.13 OAG42568.1 - 0.058 13.4 10.1 0.14 12.1 10.1 1.6 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spem1 PF15670.5 OAG42568.1 - 0.95 9.0 7.0 2 7.9 7.0 1.5 1 0 0 1 1 1 0 Spermatid maturation protein 1 Cwf_Cwc_15 PF04889.12 OAG42568.1 - 0.99 9.1 8.6 1.8 8.3 8.6 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Pkinase PF00069.25 OAG42569.1 - 1.5e-70 237.6 0.0 2e-70 237.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG42569.1 - 3.9e-33 114.8 0.0 9.2e-33 113.6 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OAG42569.1 - 0.00056 19.3 0.2 0.0012 18.2 0.2 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OAG42569.1 - 0.0024 17.2 0.0 0.0076 15.6 0.0 1.7 1 1 1 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 OAG42569.1 - 0.011 14.7 0.2 0.15 11.0 0.0 2.0 2 0 0 2 2 2 0 Haspin like kinase domain Pkinase_fungal PF17667.1 OAG42569.1 - 0.081 11.7 0.8 0.11 11.2 0.0 1.5 2 0 0 2 2 2 0 Fungal protein kinase APH PF01636.23 OAG42569.1 - 0.088 12.7 1.2 1.7 8.5 0.0 2.7 2 1 1 3 3 3 0 Phosphotransferase enzyme family AAA PF00004.29 OAG42571.1 - 1.4e-15 57.9 0.0 2.9e-15 56.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 OAG42571.1 - 5.4e-15 55.6 0.0 2e-14 53.7 0.0 2.0 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 OAG42571.1 - 3.9e-12 46.2 0.0 5.1e-11 42.6 0.0 2.3 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 OAG42571.1 - 2.3e-08 34.2 0.0 4.3e-08 33.3 0.0 1.6 1 1 0 1 1 1 1 Rad17 P-loop domain DNA_pol3_delta PF06144.13 OAG42571.1 - 6e-07 29.4 0.0 1.2e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_assoc_2 PF16193.5 OAG42571.1 - 1.1e-06 28.9 0.0 3.4e-06 27.3 0.0 1.9 1 0 0 1 1 1 1 AAA C-terminal domain AAA_30 PF13604.6 OAG42571.1 - 3.2e-06 27.0 0.0 6.3e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OAG42571.1 - 1.7e-05 25.3 0.0 0.001 19.5 0.0 2.7 2 1 1 3 3 2 1 AAA ATPase domain AAA_22 PF13401.6 OAG42571.1 - 2.2e-05 24.8 0.0 0.00011 22.5 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_11 PF13086.6 OAG42571.1 - 2.4e-05 24.2 0.0 8.4e-05 22.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 OAG42571.1 - 4.9e-05 23.3 0.2 0.00069 19.6 0.0 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 OAG42571.1 - 0.00012 21.9 0.0 0.00031 20.5 0.0 1.7 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 OAG42571.1 - 0.00034 19.9 0.0 0.00062 19.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_24 PF13479.6 OAG42571.1 - 0.001 18.8 0.0 0.0018 18.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 OAG42571.1 - 0.0019 18.2 0.0 0.16 11.9 0.0 2.3 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_3 PF07726.11 OAG42571.1 - 0.0034 17.3 0.0 0.021 14.7 0.1 2.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 OAG42571.1 - 0.0042 17.1 0.0 0.02 14.9 0.0 2.1 2 1 1 3 3 3 1 AAA domain DEAD PF00270.29 OAG42571.1 - 0.0053 16.5 0.0 0.045 13.5 0.0 2.2 1 1 1 2 2 2 1 DEAD/DEAH box helicase PhoH PF02562.16 OAG42571.1 - 0.011 15.2 0.0 0.67 9.4 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein AAA_7 PF12775.7 OAG42571.1 - 0.012 15.2 0.0 0.022 14.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_19 PF13245.6 OAG42571.1 - 0.012 16.0 0.0 0.031 14.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 OAG42571.1 - 0.014 14.8 0.1 0.078 12.3 0.1 2.2 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 OAG42571.1 - 0.023 14.9 0.0 0.042 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 OAG42571.1 - 0.034 14.7 0.0 0.059 13.9 0.0 1.4 1 0 0 1 1 1 0 ABC transporter TAFII28 PF04719.14 OAG42571.1 - 0.04 14.0 0.0 0.086 12.9 0.0 1.5 1 0 0 1 1 1 0 hTAFII28-like protein conserved region DUF2075 PF09848.9 OAG42571.1 - 0.049 12.9 0.0 0.08 12.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) TniB PF05621.11 OAG42571.1 - 0.054 12.9 0.0 0.29 10.5 0.0 2.0 2 0 0 2 2 2 0 Bacterial TniB protein RNA_helicase PF00910.22 OAG42571.1 - 0.11 12.8 0.0 0.25 11.7 0.0 1.6 1 0 0 1 1 1 0 RNA helicase P21-Arc PF04062.14 OAG42572.1 - 9.9e-75 250.4 0.0 1.1e-74 250.2 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit Gcd10p PF04189.13 OAG42573.1 - 1.3e-108 362.6 0.0 1.8e-108 362.2 0.0 1.1 1 0 0 1 1 1 1 Gcd10p family DUF3439 PF11921.8 OAG42573.1 - 0.94 9.4 7.9 2.2 8.3 7.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SSP160 PF06933.11 OAG42573.1 - 4.9 5.2 4.8 6.8 4.8 4.8 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 HAD_2 PF13419.6 OAG42574.1 - 2.6e-13 50.4 0.0 5e-13 49.5 0.0 1.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OAG42574.1 - 9.2e-06 25.6 0.0 1.7e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 OAG42574.1 - 0.00031 21.1 0.0 0.00052 20.4 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Mito_carr PF00153.27 OAG42575.1 - 1.2e-51 172.6 0.8 5e-17 61.6 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein CAAX_1 PF15895.5 OAG42575.1 - 0.16 11.9 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 CAAX box cerebral protein 1 Metallophos PF00149.28 OAG42576.1 - 7.4e-11 42.9 0.1 1.7e-10 41.8 0.1 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OAG42576.1 - 1.5e-10 41.5 0.4 7.1e-09 36.1 0.4 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Transp_inhibit PF18791.1 OAG42576.1 - 0.06 12.9 0.1 0.19 11.3 0.1 1.8 1 0 0 1 1 1 0 Transport inhibitor response 1 protein domain GFO_IDH_MocA PF01408.22 OAG42578.1 - 8.1e-19 68.6 0.0 1.3e-18 67.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DUF1805 PF08827.11 OAG42578.1 - 0.12 12.7 0.0 0.39 11.1 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) MFS_1 PF07690.16 OAG42579.1 - 1.2e-17 63.9 73.1 1e-13 51.0 43.4 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Aldo_ket_red PF00248.21 OAG42580.1 - 1.7e-62 211.3 0.0 1.9e-62 211.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Epimerase PF01370.21 OAG42581.1 - 2.2e-05 24.0 0.0 4.1e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family ERCC3_RAD25_C PF16203.5 OAG42582.1 - 4.8e-117 389.5 1.2 7.6e-117 388.9 1.2 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 OAG42582.1 - 8.6e-33 113.2 0.0 2.2e-32 111.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG42582.1 - 1.3e-15 57.8 0.0 2.4e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 OAG42582.1 - 3.8e-11 43.3 0.1 8.4e-11 42.2 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 OAG42582.1 - 4.2e-06 25.7 0.0 6.2e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain AAA_34 PF13872.6 OAG42582.1 - 0.00014 20.9 0.0 0.00023 20.1 0.0 1.3 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 DEAD PF00270.29 OAG42582.1 - 0.025 14.4 0.0 0.044 13.5 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase DUF4748 PF15932.5 OAG42583.1 - 1.2e-20 73.0 0.5 2e-20 72.3 0.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4748) CTD_bind PF04818.13 OAG42584.1 - 1.3e-11 45.1 0.7 9.8e-11 42.3 0.3 2.6 2 1 0 2 2 2 1 RNA polymerase II-binding domain. Sod_Fe_N PF00081.22 OAG42584.1 - 0.047 14.2 0.0 0.13 12.7 0.0 1.7 1 0 0 1 1 1 0 Iron/manganese superoxide dismutases, alpha-hairpin domain Hydrolase_4 PF12146.8 OAG42586.1 - 3.5e-09 36.3 0.0 7.2e-05 22.2 0.1 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OAG42586.1 - 0.033 13.8 0.1 0.071 12.7 0.1 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG42586.1 - 0.05 14.2 0.1 0.069 13.7 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Fungal_trans PF04082.18 OAG42587.1 - 5.3e-08 32.2 1.5 3.7e-07 29.5 0.0 2.5 2 1 0 2 2 2 1 Fungal specific transcription factor domain DUF4042 PF13251.6 OAG42587.1 - 0.087 12.5 3.2 3 7.5 0.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4042) IF4E PF01652.18 OAG42588.1 - 1.5e-52 177.6 0.0 2.5e-52 176.9 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Peptidase_C48 PF02902.19 OAG42588.1 - 4.6e-33 114.9 0.1 9e-33 113.9 0.1 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DUF928 PF06051.12 OAG42588.1 - 0.0062 16.4 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 Domain of Unknown Function (DUF928) BCDHK_Adom3 PF10436.9 OAG42589.1 - 4.4e-28 98.1 0.0 3.8e-27 95.1 0.0 2.1 2 0 0 2 2 2 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 OAG42589.1 - 6.7e-06 26.6 0.0 2.8e-05 24.6 0.0 1.9 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 OAG42589.1 - 0.0085 15.9 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 OAG42589.1 - 0.014 15.4 0.0 0.81 9.7 0.0 2.3 1 1 0 2 2 2 0 Histidine kinase-like ATPase domain USP7_ICP0_bdg PF12436.8 OAG42590.1 - 1.3e-86 289.9 0.2 3.5e-85 285.2 0.0 2.5 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.6 OAG42590.1 - 2.4e-71 239.7 1.6 1.5e-69 233.9 0.3 3.2 3 0 0 3 3 3 1 Ubiquitin-specific protease C-terminal UCH PF00443.29 OAG42590.1 - 1.2e-46 159.3 0.5 2.1e-46 158.5 0.5 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OAG42590.1 - 3.1e-21 76.3 0.0 1.2e-20 74.4 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.26 OAG42590.1 - 5.8e-07 29.7 0.0 1.4e-06 28.5 0.0 1.7 1 0 0 1 1 1 1 MATH domain NAD_binding_4 PF07993.12 OAG42591.1 - 3.8e-40 137.7 0.0 5.4e-40 137.2 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 OAG42591.1 - 9.7e-17 60.7 0.0 1.1e-15 57.2 0.0 2.1 1 1 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 OAG42591.1 - 2.8e-09 36.8 0.0 8.5e-08 32.0 0.0 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 OAG42591.1 - 3.8e-07 30.4 0.2 1.2e-06 28.7 0.1 2.0 2 0 0 2 2 2 1 Phosphopantetheine attachment site KR PF08659.10 OAG42591.1 - 0.11 12.4 0.6 0.56 10.1 0.6 2.1 1 1 0 1 1 1 0 KR domain DHQ_synthase PF01761.20 OAG42592.1 - 9.4e-53 179.0 0.0 1.4e-52 178.4 0.0 1.2 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.6 OAG42592.1 - 2e-10 40.8 0.0 3.4e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Methyltransf_3 PF01596.17 OAG42593.1 - 1.2e-12 47.5 0.0 1.6e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 OAG42593.1 - 1.6e-10 42.0 0.0 3e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CmcI PF04989.12 OAG42593.1 - 0.081 12.6 0.1 0.22 11.2 0.0 1.8 2 1 0 2 2 2 0 Cephalosporin hydroxylase Vps16_C PF04840.12 OAG42594.1 - 0.0032 16.6 0.0 0.0067 15.5 0.0 1.3 1 1 0 1 1 1 1 Vps16, C-terminal region Abhydrolase_3 PF07859.13 OAG42595.1 - 3.8e-30 105.3 0.0 1.3e-29 103.5 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 OAG42595.1 - 0.057 12.3 0.0 0.45 9.3 0.0 1.9 2 0 0 2 2 2 0 Carboxylesterase family EMP24_GP25L PF01105.24 OAG42596.1 - 7.2e-47 159.7 0.7 8.3e-47 159.5 0.7 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD SdrD_B PF17210.3 OAG42596.1 - 0.081 13.2 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 SdrD B-like domain adh_short PF00106.25 OAG42597.1 - 5.8e-43 146.6 0.0 7.7e-43 146.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG42597.1 - 7.9e-30 104.1 0.0 1.1e-29 103.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG42597.1 - 2.6e-10 40.5 0.0 3.8e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG42597.1 - 0.00076 19.0 0.0 0.0015 18.0 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 OAG42597.1 - 0.0011 18.4 0.0 0.0015 18.0 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) RmlD_sub_bind PF04321.17 OAG42597.1 - 0.0093 15.1 0.0 0.014 14.5 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain DHHA2 PF02833.14 OAG42598.1 - 2e-27 96.1 0.0 3.8e-27 95.2 0.0 1.4 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.20 OAG42598.1 - 5.8e-09 36.1 0.0 2.2e-08 34.3 0.0 1.9 2 1 0 2 2 2 1 DHH family TGT PF01702.18 OAG42599.1 - 7.9e-63 212.7 0.0 1.1e-62 212.3 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Transketolase_C PF02780.20 OAG42599.1 - 0.053 13.4 0.2 0.18 11.7 0.2 1.8 1 0 0 1 1 1 0 Transketolase, C-terminal domain Thymidylate_kin PF02223.17 OAG42600.1 - 1.4e-41 142.2 0.0 1.6e-41 142.0 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase CPT PF07931.12 OAG42600.1 - 9.5e-05 22.3 0.0 0.00014 21.7 0.0 1.3 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_16 PF13191.6 OAG42600.1 - 0.0037 17.6 0.0 0.0051 17.2 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_35 PF14516.6 OAG42600.1 - 0.0092 14.8 0.0 0.014 14.3 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain AAA_22 PF13401.6 OAG42600.1 - 0.017 15.4 0.0 0.053 13.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 OAG42600.1 - 0.023 15.2 0.0 0.045 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain PRK PF00485.18 OAG42600.1 - 0.025 14.3 0.0 0.035 13.8 0.0 1.2 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family KTI12 PF08433.10 OAG42600.1 - 0.026 14.0 0.0 0.044 13.2 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_14 PF13173.6 OAG42600.1 - 0.094 12.7 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 OAG42600.1 - 0.1 12.7 0.0 0.17 12.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain GIY-YIG PF01541.24 OAG42601.1 - 3.3e-12 46.5 0.0 6.2e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 GIY-YIG catalytic domain zf-HC5HC2H PF13771.6 OAG42601.1 - 0.01 16.1 5.0 0.022 15.0 5.0 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 OAG42601.1 - 0.01 16.0 3.6 0.02 15.0 3.6 1.4 1 0 0 1 1 1 0 PHD-zinc-finger like domain Zn-ribbon_8 PF09723.10 OAG42601.1 - 0.052 13.7 1.5 2 8.6 0.6 2.6 2 0 0 2 2 2 0 Zinc ribbon domain FANCL_C PF11793.8 OAG42601.1 - 0.31 11.2 6.2 0.59 10.3 6.2 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain C1_2 PF03107.16 OAG42601.1 - 2.6 8.4 6.1 0.72 10.2 2.6 1.9 2 0 0 2 2 2 0 C1 domain PLU-1 PF08429.11 OAG42602.1 - 3e-95 319.3 13.9 3.5e-92 309.2 11.4 2.2 2 0 0 2 2 2 2 PLU-1-like protein JmjC PF02373.22 OAG42602.1 - 9.5e-44 148.5 0.2 2e-43 147.4 0.2 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase ARID PF01388.21 OAG42602.1 - 1e-20 74.2 0.1 2.7e-20 72.8 0.1 1.8 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain JmjN PF02375.17 OAG42602.1 - 1.7e-16 59.8 0.7 1.7e-16 59.8 0.7 2.3 2 0 0 2 2 2 1 jmjN domain zf-C5HC2 PF02928.16 OAG42602.1 - 8.9e-14 51.6 8.1 3e-13 49.9 8.1 2.0 1 0 0 1 1 1 1 C5HC2 zinc finger PHD PF00628.29 OAG42602.1 - 2.3e-13 49.8 38.5 4.3e-09 36.1 10.1 3.5 3 0 0 3 3 3 2 PHD-finger Prok-RING_1 PF14446.6 OAG42602.1 - 0.0061 16.5 6.4 0.0061 16.5 6.4 2.7 2 1 0 2 2 2 1 Prokaryotic RING finger family 1 zf-PHD-like PF15446.6 OAG42602.1 - 0.36 10.4 13.0 0.33 10.5 3.8 2.7 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain zf-RanBP PF00641.18 OAG42602.1 - 0.45 9.9 8.8 2 7.8 0.4 2.7 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others C1_1 PF00130.22 OAG42602.1 - 2.9 7.8 23.6 0.082 12.8 2.3 3.7 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.6 OAG42602.1 - 3 7.5 18.1 0.056 13.0 5.1 2.8 2 0 0 2 2 2 0 PHD-finger PHD_4 PF16866.5 OAG42602.1 - 9.5 6.4 23.1 3.4 7.8 6.5 2.8 2 0 0 2 2 2 0 PHD-finger MTHFR PF02219.17 OAG42603.1 - 8.5e-93 310.8 0.0 2.4e-92 309.3 0.0 1.6 1 1 0 1 1 1 1 Methylenetetrahydrofolate reductase PEX11 PF05648.14 OAG42604.1 - 3.1e-08 33.4 0.0 5.1e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Neisseria_TspB PF05616.13 OAG42604.1 - 7.5 4.9 8.1 11 4.4 8.1 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Lactamase_B PF00753.27 OAG42605.1 - 0.00073 19.6 3.0 0.0024 17.9 2.7 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily adh_short_C2 PF13561.6 OAG42606.1 - 4.2e-38 131.2 0.0 6.4e-38 130.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG42606.1 - 3.2e-33 114.9 0.0 4.1e-33 114.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 OAG42606.1 - 0.15 11.5 0.0 0.28 10.6 0.0 1.4 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family DUF3638 PF12340.8 OAG42607.1 - 6e-75 251.5 0.0 9.8e-75 250.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 OAG42607.1 - 8.5e-13 47.4 0.5 1.9e-12 46.4 0.5 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) WW PF00397.26 OAG42608.1 - 0.0002 21.4 3.4 0.0002 21.4 3.4 2.1 2 0 0 2 2 2 1 WW domain DUF3523 PF12037.8 OAG42608.1 - 0.22 10.9 9.7 0.31 10.4 9.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3523) PAT1 PF09770.9 OAG42608.1 - 1.4 7.1 7.9 1.6 6.9 7.9 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SAP25 PF15476.6 OAG42609.1 - 0.018 14.7 0.0 0.024 14.3 0.0 1.2 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP25 DUF2196 PF09962.9 OAG42609.1 - 0.13 12.3 0.1 0.27 11.3 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2196) GGACT PF06094.12 OAG42610.1 - 2.9e-15 56.9 0.2 4.4e-15 56.4 0.2 1.2 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like Septin PF00735.18 OAG42611.1 - 2.9e-113 377.8 0.3 4e-113 377.4 0.3 1.2 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 OAG42611.1 - 1.8e-07 31.2 0.0 4e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OAG42611.1 - 5.7e-06 26.3 0.0 3.5e-05 23.8 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 OAG42611.1 - 1.2e-05 25.0 3.5 6e-05 22.7 0.1 2.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 OAG42611.1 - 0.0016 18.7 0.7 0.0051 17.1 0.0 2.1 2 1 0 2 2 2 1 AAA domain Roc PF08477.13 OAG42611.1 - 0.002 18.3 0.1 0.0044 17.2 0.1 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Pox_A32 PF04665.12 OAG42611.1 - 0.002 17.6 0.1 0.0035 16.8 0.1 1.3 1 0 0 1 1 1 1 Poxvirus A32 protein AIG1 PF04548.16 OAG42611.1 - 0.0071 15.7 0.0 0.013 14.8 0.0 1.4 1 0 0 1 1 1 1 AIG1 family IIGP PF05049.13 OAG42611.1 - 0.0081 15.3 0.0 0.014 14.5 0.0 1.4 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) AAA_24 PF13479.6 OAG42611.1 - 0.016 14.9 0.0 0.028 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Ras PF00071.22 OAG42611.1 - 0.016 14.8 0.2 0.068 12.8 0.1 2.1 2 0 0 2 2 2 0 Ras family NACHT PF05729.12 OAG42611.1 - 0.024 14.6 0.0 0.044 13.7 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.6 OAG42611.1 - 0.03 14.7 1.0 0.094 13.1 0.1 2.4 2 1 0 2 2 2 0 AAA ATPase domain T2SSE PF00437.20 OAG42611.1 - 0.035 13.2 0.2 0.12 11.5 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein KAP_NTPase PF07693.14 OAG42611.1 - 0.038 13.2 0.0 0.047 12.9 0.0 1.5 1 1 0 1 1 1 0 KAP family P-loop domain AAA_25 PF13481.6 OAG42611.1 - 0.045 13.3 0.2 0.52 9.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain FOXP-CC PF16159.5 OAG42611.1 - 0.055 14.1 1.0 0.16 12.6 0.2 2.2 1 1 1 2 2 1 0 FOXP coiled-coil domain ABC_tran PF00005.27 OAG42611.1 - 0.061 13.8 0.3 0.23 12.0 0.0 2.0 2 1 0 2 2 2 0 ABC transporter Sigma54_activat PF00158.26 OAG42611.1 - 0.065 12.9 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain RNA_helicase PF00910.22 OAG42611.1 - 0.1 13.0 0.0 0.27 11.6 0.0 1.8 1 0 0 1 1 1 0 RNA helicase PduV-EutP PF10662.9 OAG42611.1 - 0.11 12.3 0.4 4.2 7.1 0.4 2.6 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.23 OAG42611.1 - 0.39 10.7 5.4 2.9 7.9 0.1 2.9 2 1 1 3 3 3 0 Dynamin family AAA_11 PF13086.6 OAG42611.1 - 6 6.6 6.5 22 4.7 0.1 2.2 2 0 0 2 2 2 0 AAA domain WD40 PF00400.32 OAG42612.1 - 2e-38 129.7 28.5 2.7e-08 34.3 0.2 12.4 12 0 0 12 12 12 7 WD domain, G-beta repeat Utp12 PF04003.12 OAG42612.1 - 6.7e-23 81.0 0.0 1.1e-22 80.4 0.0 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 OAG42612.1 - 1.3e-15 57.5 0.0 0.63 10.4 0.0 8.8 4 2 4 9 9 9 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OAG42612.1 - 3.7e-07 29.4 0.0 2.9 6.8 0.0 5.3 4 2 2 6 6 6 4 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 OAG42612.1 - 0.00014 20.6 11.4 0.3 9.7 0.2 4.6 2 2 3 5 5 5 3 Nucleoporin Nup120/160 PQQ_3 PF13570.6 OAG42612.1 - 0.1 13.1 2.3 40 4.9 0.2 4.3 4 0 0 4 4 4 0 PQQ-like domain Methyltransf_32 PF13679.6 OAG42613.1 - 3e-25 89.0 0.2 6.1e-25 88.0 0.2 1.6 1 1 0 1 1 1 1 Methyltransferase domain NUDIX PF00293.28 OAG42614.1 - 7.4e-16 58.4 0.3 1.4e-15 57.5 0.3 1.4 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.11 OAG42614.1 - 1.3e-10 41.8 0.0 5.8e-10 39.8 0.0 2.0 3 0 0 3 3 3 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.11 OAG42614.1 - 3.7e-07 29.7 2.5 6.1e-07 29.0 2.5 1.3 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain DpnI PF06044.12 OAG42614.1 - 0.037 13.7 0.0 0.12 12.0 0.0 1.7 2 0 0 2 2 2 0 Dam-replacing family FMO-like PF00743.19 OAG42615.1 - 1.9e-13 49.7 0.0 6e-13 48.1 0.0 1.7 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 OAG42615.1 - 2.3e-13 50.1 0.0 5.1e-11 42.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG42615.1 - 1.8e-10 40.9 0.0 3.1e-08 33.7 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 OAG42615.1 - 1.6e-08 34.2 0.0 6.8e-08 32.1 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG42615.1 - 5.2e-08 32.4 0.0 5.8e-07 29.0 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 OAG42615.1 - 2.5e-05 24.3 0.1 0.06 13.3 0.0 3.8 3 1 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.24 OAG42615.1 - 3.6e-05 23.5 0.0 0.066 12.8 0.0 2.6 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 OAG42615.1 - 4.8e-05 23.8 1.2 0.076 13.6 0.4 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 OAG42615.1 - 0.041 13.3 0.1 0.072 12.4 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GIDA PF01134.22 OAG42615.1 - 0.22 10.5 0.0 9 5.3 0.0 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_4 PF07993.12 OAG42616.1 - 5.9e-33 114.1 0.0 8.8e-33 113.6 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 OAG42616.1 - 1.6e-22 79.7 0.0 3.1e-22 78.8 0.0 1.5 1 1 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 OAG42616.1 - 3.4e-10 39.8 0.0 8.1e-10 38.6 0.0 1.7 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 OAG42616.1 - 3.2e-08 33.8 0.0 1.1e-07 32.1 0.0 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site GDP_Man_Dehyd PF16363.5 OAG42616.1 - 0.0021 17.5 0.0 0.0042 16.5 0.0 1.5 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Cyclase PF04199.13 OAG42617.1 - 1.9e-12 47.6 0.0 2.5e-11 44.0 0.0 2.0 1 1 1 2 2 2 1 Putative cyclase Cupin_3 PF05899.12 OAG42617.1 - 0.0058 16.3 0.0 0.015 15.0 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Sugar_tr PF00083.24 OAG42618.1 - 1.8e-70 238.1 17.2 2e-70 237.9 17.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG42618.1 - 4.9e-19 68.5 32.3 8.3e-19 67.7 25.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 OAG42618.1 - 0.00072 18.2 2.6 0.00072 18.2 2.6 2.4 2 0 0 2 2 2 1 MFS/sugar transport protein Mvb12 PF09452.10 OAG42619.1 - 0.11 12.9 0.0 1.2 9.6 0.0 2.2 2 0 0 2 2 2 0 ESCRT-I subunit Mvb12 CN_hydrolase PF00795.22 OAG42620.1 - 6.8e-32 110.8 0.0 1.3e-31 109.9 0.0 1.5 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Pyr_redox_2 PF07992.14 OAG42620.1 - 8.9e-16 58.0 0.0 2.3e-13 50.0 0.0 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_synthase PF02540.17 OAG42620.1 - 1.5e-15 57.0 0.0 6.5e-15 54.9 0.0 1.9 1 1 0 1 1 1 1 NAD synthase Pyr_redox_3 PF13738.6 OAG42620.1 - 5.6e-11 42.3 0.0 3.5e-09 36.4 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG42620.1 - 1e-10 41.6 0.0 2.5e-09 37.2 0.0 3.2 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.19 OAG42620.1 - 2e-06 26.5 0.3 1.2e-05 23.9 0.1 2.1 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox PF00070.27 OAG42620.1 - 1.4e-05 25.5 0.3 0.059 13.9 0.2 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG42620.1 - 3.2e-05 23.3 0.0 0.00057 19.1 0.0 2.4 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.24 OAG42620.1 - 3.5e-05 23.1 0.0 6.5e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 OAG42620.1 - 0.00088 18.6 0.1 0.038 13.2 0.0 2.4 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 OAG42620.1 - 0.0011 18.6 2.2 0.0057 16.3 0.0 3.1 3 1 0 3 3 3 1 FAD dependent oxidoreductase HI0933_like PF03486.14 OAG42620.1 - 0.0018 17.0 1.1 0.015 14.0 0.2 2.3 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 OAG42620.1 - 0.0039 16.6 0.2 0.011 15.2 0.1 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 OAG42620.1 - 0.018 15.4 0.0 1.7 9.2 0.0 3.1 3 0 0 3 3 3 0 Putative NAD(P)-binding RelE PF06296.12 OAG42620.1 - 0.02 15.0 0.0 0.31 11.1 0.0 2.5 3 0 0 3 3 2 0 RelE toxin of RelE / RelB toxin-antitoxin system NAD_binding_9 PF13454.6 OAG42620.1 - 0.031 14.3 0.2 2.4 8.1 0.0 3.5 4 0 0 4 4 4 0 FAD-NAD(P)-binding Shikimate_DH PF01488.20 OAG42620.1 - 0.034 14.2 0.0 0.27 11.3 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase GIDA PF01134.22 OAG42620.1 - 0.034 13.2 0.1 0.034 13.2 0.1 2.4 4 0 0 4 4 4 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 OAG42620.1 - 0.09 11.8 0.0 2 7.3 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 OAG42620.1 - 0.18 11.1 0.2 1.3 8.3 0.0 2.3 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain GTP_cyclohydroI PF01227.22 OAG42621.1 - 4.5e-73 244.5 0.1 6.8e-73 243.9 0.1 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 OAG42621.1 - 0.0036 17.4 0.0 0.012 15.7 0.0 1.8 2 0 0 2 2 2 1 QueF-like protein Abhydrolase_6 PF12697.7 OAG42622.1 - 8.3e-17 62.5 0.0 9.6e-17 62.3 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF900 PF05990.12 OAG42622.1 - 0.097 12.2 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Methyltransf_11 PF08241.12 OAG42623.1 - 4.9e-16 59.1 0.0 9.1e-16 58.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAG42623.1 - 9.5e-16 57.8 0.0 2.5e-15 56.4 0.0 1.6 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 OAG42623.1 - 3.8e-14 53.2 0.0 8e-14 52.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG42623.1 - 6e-11 42.4 0.0 7.8e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAG42623.1 - 5.2e-08 32.9 0.0 7.8e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG42623.1 - 2.1e-07 31.6 0.0 4.2e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Catalase PF00199.19 OAG42623.1 - 0.022 13.9 0.0 0.029 13.5 0.0 1.2 1 0 0 1 1 1 0 Catalase Methyltransf_PK PF05891.12 OAG42623.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Transglut_core PF01841.19 OAG42624.1 - 3.2e-11 43.7 0.1 6.9e-11 42.6 0.1 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily SH3_2 PF07653.17 OAG42624.1 - 1.2e-06 28.1 0.0 2.8e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 OAG42624.1 - 9.1e-06 25.2 0.0 1.7e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 OAG42624.1 - 0.04 13.8 0.1 0.14 12.0 0.1 1.9 2 0 0 2 2 2 0 Variant SH3 domain MFS_1 PF07690.16 OAG42626.1 - 4.9e-34 117.8 26.2 1.2e-33 116.5 26.2 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily 5TM-5TMR_LYT PF07694.12 OAG42626.1 - 0.11 12.0 7.0 0.76 9.3 0.0 3.1 3 0 0 3 3 3 0 5TMR of 5TMR-LYT GCS PF03074.16 OAG42627.1 - 4.8e-124 414.4 0.0 6.4e-124 414.0 0.0 1.2 1 0 0 1 1 1 1 Glutamate-cysteine ligase Fungal_trans PF04082.18 OAG42627.1 - 3.1e-08 33.0 1.8 8e-08 31.6 1.8 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain GCS2 PF04107.13 OAG42627.1 - 0.0023 17.3 0.0 0.0046 16.3 0.0 1.4 1 0 0 1 1 1 1 Glutamate-cysteine ligase family 2(GCS2) RPE65 PF03055.15 OAG42628.1 - 1.9e-100 337.3 0.0 2.3e-100 337.0 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein PhyH PF05721.13 OAG42629.1 - 3e-19 70.1 0.0 4e-19 69.7 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) zf-RING_11 PF17123.5 OAG42629.1 - 0.21 11.4 0.0 0.44 10.3 0.0 1.6 1 0 0 1 1 1 0 RING-like zinc finger AA_permease PF00324.21 OAG42630.1 - 9.1e-103 344.4 46.9 1e-102 344.2 46.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAG42630.1 - 2.8e-21 75.9 51.7 3.8e-21 75.4 51.7 1.1 1 0 0 1 1 1 1 Amino acid permease Nucleos_tra2_C PF07662.13 OAG42630.1 - 4.2 7.2 9.7 20 4.9 0.7 3.0 2 1 0 2 2 2 0 Na+ dependent nucleoside transporter C-terminus WD40 PF00400.32 OAG42631.1 - 3.5e-24 84.6 10.5 2.3e-07 31.4 0.6 7.4 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG42631.1 - 5.8e-14 52.2 0.0 0.023 15.0 0.0 5.0 1 1 3 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain PQQ PF01011.21 OAG42631.1 - 3.6e-05 23.5 0.0 0.3 11.1 0.0 3.6 3 0 0 3 3 3 2 PQQ enzyme repeat BBS2_Mid PF14783.6 OAG42631.1 - 0.00086 19.3 0.9 0.68 10.0 0.1 4.5 3 1 1 4 4 4 1 Ciliary BBSome complex subunit 2, middle region Ge1_WD40 PF16529.5 OAG42631.1 - 0.0026 16.8 0.1 2.5 7.0 0.0 3.6 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_2 PF13360.6 OAG42631.1 - 0.012 15.2 5.8 0.021 14.4 3.0 2.2 1 1 1 2 2 2 0 PQQ-like domain Nup160 PF11715.8 OAG42631.1 - 0.02 13.6 0.4 4.5 5.8 0.0 3.1 2 1 0 3 3 3 0 Nucleoporin Nup120/160 PQQ_3 PF13570.6 OAG42631.1 - 0.14 12.7 9.2 24 5.6 0.0 5.2 5 1 1 6 6 6 0 PQQ-like domain XRN_M PF17846.1 OAG42632.1 - 9.4e-100 334.6 4.7 1.6e-99 333.9 4.7 1.3 1 0 0 1 1 1 1 Xrn1 helical domain XRN_N PF03159.18 OAG42632.1 - 1.3e-97 326.1 0.0 2.5e-97 325.1 0.0 1.5 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN1_D1 PF18332.1 OAG42632.1 - 4.2e-75 251.7 0.0 4.2e-75 251.7 0.0 2.1 2 0 0 2 2 2 1 Exoribonuclease Xrn1 D1 domain XRN1_D2_D3 PF18334.1 OAG42632.1 - 6.5e-33 112.8 0.0 2.4e-32 111.0 0.0 2.1 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D2/D3 domain ACT_7 PF13840.6 OAG42632.1 - 9.7e-24 82.9 0.0 3.1e-15 55.7 0.0 3.0 2 1 0 2 2 2 2 ACT domain SH3_12 PF18129.1 OAG42632.1 - 9.8e-24 83.2 0.4 8.2e-23 80.3 0.2 2.5 2 0 0 2 2 2 1 Xrn1 SH3-like domain Xrn1_D3 PF18194.1 OAG42632.1 - 2.3e-09 37.2 0.2 6.9e-09 35.7 0.2 1.8 1 0 0 1 1 1 1 Exoribonuclease 1 Domain-3 Phage_TAC_4 PF08748.11 OAG42632.1 - 0.087 13.1 0.6 0.27 11.6 0.6 1.8 1 0 0 1 1 1 0 Phage tail assembly chaperone CAF1C_H4-bd PF12265.8 OAG42633.1 - 6.6e-28 96.8 0.2 3.8e-27 94.3 0.2 2.3 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 OAG42633.1 - 2.3e-26 91.5 7.5 5.7e-06 27.0 0.0 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat Ge1_WD40 PF16529.5 OAG42633.1 - 0.13 11.2 0.1 16 4.3 0.0 2.9 3 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Fungal_trans_2 PF11951.8 OAG42634.1 - 6.5e-12 45.0 0.1 1.1e-11 44.2 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain RIX1 PF08167.12 OAG42634.1 - 0.057 13.2 0.1 0.098 12.4 0.1 1.3 1 0 0 1 1 1 0 rRNA processing/ribosome biogenesis ADH_N PF08240.12 OAG42635.1 - 2.4e-09 37.0 0.0 4.2e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG42635.1 - 3.2e-07 30.4 0.0 6.3e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAG42635.1 - 0.062 14.4 0.0 0.16 13.0 0.0 1.7 2 0 0 2 2 2 0 Zinc-binding dehydrogenase TAF6_C PF07571.13 OAG42636.1 - 8.6e-30 102.9 0.0 1.9e-29 101.8 0.0 1.6 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain TAF PF02969.17 OAG42636.1 - 6.5e-24 83.9 0.1 1.5e-23 82.7 0.1 1.7 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.24 OAG42636.1 - 0.0033 17.8 0.4 0.0072 16.7 0.2 1.7 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 OAG42636.1 - 0.0038 17.5 0.1 0.017 15.4 0.0 2.1 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 OAG42636.1 - 0.052 13.6 0.6 0.15 12.2 0.1 1.9 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit DUF3430 PF11912.8 OAG42637.1 - 0.0024 18.0 3.7 0.003 17.6 3.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) TMEM51 PF15345.6 OAG42637.1 - 0.054 13.3 0.0 0.077 12.8 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 DUF4690 PF15756.5 OAG42637.1 - 0.36 11.5 5.6 0.1 13.2 1.0 2.3 2 0 0 2 2 2 0 Small Novel Rich in Cartilage DUF3292 PF11696.8 OAG42639.1 - 0.00011 20.8 0.6 0.32 9.3 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF3292) Reticulon PF02453.17 OAG42639.1 - 0.21 11.5 5.8 0.21 11.6 0.9 2.3 2 0 0 2 2 2 0 Reticulon PRT_C PF08372.10 OAG42639.1 - 0.59 9.9 2.8 0.31 10.8 0.2 1.8 2 0 0 2 2 2 0 Plant phosphoribosyltransferase C-terminal RmlD_sub_bind PF04321.17 OAG42640.1 - 6.8e-58 196.0 0.0 8.7e-58 195.7 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 OAG42640.1 - 7.2e-25 87.8 0.0 9.5e-25 87.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAG42640.1 - 5.7e-15 55.5 0.1 8e-14 51.8 0.1 2.0 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 OAG42640.1 - 4e-11 42.6 1.0 1.6e-09 37.4 0.3 2.9 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 OAG42640.1 - 6.8e-10 38.4 0.1 2.2e-08 33.5 0.1 2.1 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 OAG42640.1 - 2e-09 37.0 0.1 7.6e-07 28.5 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein KR PF08659.10 OAG42640.1 - 0.024 14.6 0.1 3 7.7 0.0 2.4 2 0 0 2 2 2 0 KR domain SET PF00856.28 OAG42642.1 - 1e-11 45.5 0.0 1.9e-10 41.4 0.0 3.1 2 1 0 2 2 2 1 SET domain preSET_CXC PF18264.1 OAG42642.1 - 2e-08 34.5 14.7 2e-08 34.5 14.7 3.5 4 0 0 4 4 4 1 CXC domain Ezh2_MCSS PF18600.1 OAG42642.1 - 0.0023 17.5 0.2 0.0061 16.2 0.2 1.6 1 0 0 1 1 1 1 MCSS domain Pil1 PF13805.6 OAG42643.1 - 1.7e-126 421.1 0.0 2.2e-126 420.8 0.0 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 DUF2385 PF09539.10 OAG42643.1 - 0.023 15.2 0.3 1.6 9.3 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2385) CAF20 PF17052.5 OAG42643.1 - 0.028 14.6 0.6 0.072 13.2 0.6 1.7 1 0 0 1 1 1 0 Cap associated factor FAM92 PF06730.11 OAG42643.1 - 0.039 13.4 1.9 0.059 12.8 0.8 1.7 1 1 0 2 2 2 0 FAM92 protein HD_2 PF12917.7 OAG42643.1 - 0.06 13.1 0.1 4.4 7.0 0.0 2.3 2 0 0 2 2 2 0 HD containing hydrolase-like enzyme Atg14 PF10186.9 OAG42643.1 - 0.16 11.0 2.6 5.4 6.0 0.2 2.3 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 SUR7 PF06687.12 OAG42644.1 - 2.9e-34 118.6 11.0 3.8e-34 118.2 11.0 1.1 1 0 0 1 1 1 1 SUR7/PalI family LigD_N PF13298.6 OAG42645.1 - 2.3e-21 76.1 0.0 3.9e-21 75.3 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase Ligase (LigD) Pirin PF02678.16 OAG42646.1 - 3.3e-21 75.3 1.6 9.9e-21 73.8 1.6 1.7 1 1 0 1 1 1 1 Pirin Cupin_2 PF07883.11 OAG42646.1 - 7.3e-08 32.0 4.3 2.3e-05 24.0 1.2 3.1 2 1 0 2 2 2 2 Cupin domain MelC1 PF06236.11 OAG42646.1 - 0.009 16.1 0.0 0.016 15.3 0.0 1.4 1 0 0 1 1 1 1 Tyrosinase co-factor MelC1 Pirin_C_2 PF17954.1 OAG42646.1 - 0.018 15.2 0.0 0.23 11.7 0.0 2.5 2 1 0 2 2 2 0 Quercetinase C-terminal cupin domain Cupin_1 PF00190.22 OAG42646.1 - 0.038 13.6 0.0 0.07 12.7 0.0 1.4 1 0 0 1 1 1 0 Cupin ABC_tran PF00005.27 OAG42647.1 - 1.6e-49 167.9 0.0 4.5e-29 101.7 0.1 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 OAG42647.1 - 8.5e-35 120.7 25.5 1.3e-25 90.6 14.1 4.1 4 1 0 4 4 4 2 ABC transporter transmembrane region SMC_N PF02463.19 OAG42647.1 - 5e-11 42.5 1.6 0.00022 20.7 0.1 4.5 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 OAG42647.1 - 0.0003 20.8 0.2 0.066 13.3 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OAG42647.1 - 0.00064 19.7 0.3 0.74 9.7 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase DUF87 PF01935.17 OAG42647.1 - 0.00071 19.7 1.7 0.32 11.1 0.1 2.6 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_29 PF13555.6 OAG42647.1 - 0.0022 17.7 0.2 1.6 8.6 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 OAG42647.1 - 0.0028 17.9 0.1 5.8 7.2 0.1 3.2 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OAG42647.1 - 0.0037 17.7 0.2 0.67 10.3 0.2 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 OAG42647.1 - 0.019 15.4 3.5 0.23 11.9 0.1 2.7 3 0 0 3 3 2 0 AAA domain AAA_25 PF13481.6 OAG42647.1 - 0.026 14.1 0.0 2.5 7.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 OAG42647.1 - 0.026 13.6 0.0 1.8 7.5 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_21 PF13304.6 OAG42647.1 - 0.041 13.7 0.3 8.9 6.0 0.0 3.6 4 0 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_10 PF12846.7 OAG42647.1 - 0.046 12.6 0.0 1.8 7.4 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain MeaB PF03308.16 OAG42647.1 - 0.077 12.0 0.5 0.25 10.3 0.1 1.9 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB IstB_IS21 PF01695.17 OAG42647.1 - 0.087 12.6 0.2 4.7 6.9 0.0 2.7 3 0 0 3 3 2 0 IstB-like ATP binding protein AAA_30 PF13604.6 OAG42647.1 - 0.13 11.9 0.2 13 5.4 0.0 2.8 3 0 0 3 3 3 0 AAA domain DUF2075 PF09848.9 OAG42647.1 - 0.13 11.4 0.0 1.8 7.8 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) NACHT PF05729.12 OAG42647.1 - 0.38 10.7 1.7 1.2 9.0 0.1 2.5 3 0 0 3 3 3 0 NACHT domain Peptidase_M28 PF04389.17 OAG42648.1 - 3.9e-32 111.6 0.0 6.1e-32 110.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 MutS_V PF00488.21 OAG42651.1 - 5.2e-66 222.3 0.1 1.1e-65 221.2 0.1 1.6 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 OAG42651.1 - 7.1e-42 143.8 0.1 1.4e-41 142.8 0.1 1.6 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 OAG42651.1 - 3.5e-32 111.0 0.0 8.6e-32 109.7 0.0 1.7 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 OAG42651.1 - 7.1e-15 55.5 0.0 1.9e-14 54.1 0.0 1.7 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 OAG42651.1 - 6.3e-09 36.1 0.1 1.7e-08 34.7 0.1 1.8 1 0 0 1 1 1 1 MutS family domain IV AAA_23 PF13476.6 OAG42651.1 - 0.0015 19.1 1.0 0.011 16.3 0.1 2.7 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 OAG42651.1 - 0.034 13.9 0.1 0.081 12.7 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_27 PF13514.6 OAG42651.1 - 0.036 13.6 0.0 0.09 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.6 OAG42651.1 - 0.061 13.1 0.7 0.23 11.2 0.1 2.2 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 OAG42651.1 - 0.094 13.1 0.2 0.67 10.3 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain AAA_15 PF13175.6 OAG42651.1 - 0.56 9.9 2.3 1.9 8.1 0.2 2.3 2 0 0 2 2 2 0 AAA ATPase domain tRNA-synt_1b PF00579.25 OAG42652.1 - 3.2e-73 246.6 0.0 4.1e-73 246.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) TyrRSs_C PF16714.5 OAG42652.1 - 4e-43 146.0 0.0 8.5e-43 145.0 0.0 1.6 1 0 0 1 1 1 1 Tyrosyl-tRNA synthetase C-terminal domain S4 PF01479.25 OAG42652.1 - 0.095 12.4 0.0 0.24 11.2 0.0 1.6 1 0 0 1 1 1 0 S4 domain YcxB PF14317.6 OAG42652.1 - 0.1 12.3 0.2 0.22 11.3 0.2 1.5 1 0 0 1 1 1 0 YcxB-like protein Beta-lactamase PF00144.24 OAG42653.1 - 5.2e-68 229.7 0.0 6.2e-68 229.5 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase FMO-like PF00743.19 OAG42654.1 - 7.7e-13 47.7 0.0 1.1e-11 43.9 0.0 2.4 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OAG42654.1 - 2.3e-11 43.5 0.0 4.8e-09 35.9 0.0 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG42654.1 - 2e-07 30.5 0.0 1.8e-05 24.1 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 OAG42654.1 - 4.1e-07 29.5 0.0 0.00063 19.1 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG42654.1 - 4.2e-06 26.9 1.0 7.9e-06 26.0 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.20 OAG42654.1 - 5.2e-06 26.6 0.0 0.014 15.5 0.0 2.4 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase DAO PF01266.24 OAG42654.1 - 0.0085 15.7 0.1 0.58 9.7 0.0 2.9 2 1 0 2 2 2 1 FAD dependent oxidoreductase NatB_MDM20 PF09797.9 OAG42654.1 - 0.041 12.8 0.1 0.064 12.2 0.1 1.2 1 0 0 1 1 1 0 N-acetyltransferase B complex (NatB) non catalytic subunit 2-Hacid_dh_C PF02826.19 OAG42654.1 - 0.078 12.3 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain adh_short PF00106.25 OAG42655.1 - 2.9e-40 137.8 0.0 3.8e-40 137.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG42655.1 - 2.5e-31 109.1 0.0 3.3e-31 108.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG42655.1 - 0.0005 20.0 0.0 0.011 15.6 0.0 2.2 2 0 0 2 2 2 1 KR domain TrkA_N PF02254.18 OAG42655.1 - 0.0093 16.2 0.1 0.038 14.2 0.0 1.9 2 0 0 2 2 2 1 TrkA-N domain DFP PF04127.15 OAG42655.1 - 0.015 15.2 0.0 0.052 13.4 0.1 1.8 2 1 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein YjeF_N PF03853.15 OAG42655.1 - 0.018 14.9 0.0 0.032 14.1 0.0 1.4 1 0 0 1 1 1 0 YjeF-related protein N-terminus Epimerase PF01370.21 OAG42655.1 - 0.067 12.6 0.0 0.15 11.5 0.0 1.6 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family HI0933_like PF03486.14 OAG42655.1 - 0.11 11.1 0.0 0.15 10.7 0.0 1.1 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_2 PF03446.15 OAG42655.1 - 0.17 12.0 0.0 0.39 10.9 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Fungal_trans PF04082.18 OAG42656.1 - 7.2e-10 38.3 0.6 1.3e-09 37.5 0.6 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG42656.1 - 1.1e-06 28.6 12.2 2.3e-06 27.6 12.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FMO-like PF00743.19 OAG42657.1 - 2.9e-17 62.3 0.1 4.8e-17 61.6 0.1 1.2 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OAG42657.1 - 3.2e-14 52.9 0.0 1.2e-13 51.0 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAG42657.1 - 3.1e-13 49.6 0.0 2e-10 40.4 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG42657.1 - 1.6e-08 34.6 0.0 3.7e-07 30.3 0.0 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 OAG42657.1 - 2.2e-08 33.6 0.2 5.7e-08 32.3 0.0 1.7 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 OAG42657.1 - 2.3e-07 31.2 0.6 0.038 14.5 0.0 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAG42657.1 - 0.0011 18.6 0.2 0.59 9.7 0.2 3.0 1 1 1 2 2 2 2 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.19 OAG42657.1 - 0.0072 15.7 0.0 0.013 14.8 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PHA_synth_III_E PF09712.10 OAG42657.1 - 0.028 13.5 0.0 0.048 12.8 0.0 1.3 1 0 0 1 1 1 0 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) NAD_binding_9 PF13454.6 OAG42657.1 - 0.079 12.9 0.1 0.76 9.8 0.1 2.7 2 1 0 2 2 2 0 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 OAG42657.1 - 0.08 12.2 0.9 4.5 6.5 0.0 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain PS_Dcarbxylase PF02666.15 OAG42657.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Phosphatidylserine decarboxylase Shikimate_DH PF01488.20 OAG42657.1 - 0.13 12.3 0.1 0.39 10.8 0.0 1.8 2 0 0 2 2 1 0 Shikimate / quinate 5-dehydrogenase TRI12 PF06609.13 OAG42658.1 - 1.1e-62 212.4 32.3 1.4e-62 212.0 32.3 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG42658.1 - 1.2e-17 63.9 63.1 7.9e-17 61.2 57.6 3.2 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG42658.1 - 3.6e-13 49.2 3.0 3.6e-13 49.2 3.0 3.1 4 0 0 4 4 4 1 Sugar (and other) transporter Pox_A14 PF05767.12 OAG42658.1 - 0.19 11.9 2.2 0.3 11.3 0.2 2.5 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 SelP_N PF04592.14 OAG42658.1 - 4.1 6.7 5.9 5.8 6.2 5.9 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region SnoaL_3 PF13474.6 OAG42659.1 - 0.0036 17.6 0.0 0.0069 16.6 0.0 1.4 1 1 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 OAG42659.1 - 0.019 15.4 0.0 0.04 14.3 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4440) PBP1_TM PF14812.6 OAG42660.1 - 0.027 14.8 0.9 5.9 7.3 0.1 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pheromone PF08015.11 OAG42660.1 - 2.2 9.4 4.7 8.1 7.6 3.3 2.6 2 1 0 2 2 2 0 Fungal mating-type pheromone DHR-2 PF06920.13 OAG42661.1 - 0.14 10.8 0.7 0.21 10.2 0.0 1.5 2 0 0 2 2 2 0 Dock homology region 2 Ank_2 PF12796.7 OAG42662.1 - 2.9e-20 72.7 3.1 2.2e-10 41.0 0.5 4.4 4 1 0 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAG42662.1 - 2.2e-13 50.4 3.6 1.4e-07 31.9 0.1 6.0 5 2 2 7 7 7 3 Ankyrin repeats (many copies) Ank PF00023.30 OAG42662.1 - 7.3e-10 38.8 10.0 0.021 15.3 0.0 4.9 6 0 0 6 6 6 3 Ankyrin repeat Ank_3 PF13606.6 OAG42662.1 - 3.8e-09 36.0 3.3 0.2 12.3 0.0 5.8 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 OAG42662.1 - 9.8e-09 35.3 4.2 0.0036 17.6 0.2 5.0 2 1 3 5 5 5 2 Ankyrin repeats (many copies) TAFII28 PF04719.14 OAG42664.1 - 5e-21 74.6 1.3 2.3e-20 72.5 1.3 2.0 1 1 0 1 1 1 1 hTAFII28-like protein conserved region AT_hook PF02178.19 OAG42664.1 - 0.0045 16.7 1.9 0.019 14.8 1.9 2.2 1 0 0 1 1 1 1 AT hook motif Phage_Gp23 PF10669.9 OAG42664.1 - 0.29 11.5 12.0 0.39 11.0 5.9 2.2 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) DUF5401 PF17380.2 OAG42664.1 - 2.1 6.3 20.7 0.095 10.8 7.6 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5401) CENP-X PF09415.10 OAG42664.1 - 8.9 6.7 8.6 0.36 11.2 1.2 2.5 2 0 0 2 2 2 0 CENP-S associating Centromere protein X Frag1 PF10277.9 OAG42665.1 - 0.0013 18.3 4.8 0.0019 17.8 4.8 1.2 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family Hexokinase_2 PF03727.16 OAG42666.1 - 1.2e-71 241.0 0.0 1.7e-71 240.5 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 OAG42666.1 - 1.3e-69 234.1 0.0 1.9e-69 233.5 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Abhydrolase_6 PF12697.7 OAG42667.1 - 1.8e-09 38.6 14.6 3.2e-09 37.7 14.6 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_8 PF06259.12 OAG42667.1 - 0.037 13.7 0.1 0.071 12.7 0.1 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase Pkinase PF00069.25 OAG42668.1 - 4.3e-14 52.5 0.0 6.9e-14 51.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 OAG42668.1 - 1.5e-08 33.8 0.0 2e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_Tyr PF07714.17 OAG42668.1 - 1e-06 28.3 0.0 1.6e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OAG42668.1 - 0.0007 19.6 0.0 0.0015 18.5 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family p450 PF00067.22 OAG42669.1 - 4.9e-47 160.7 0.0 4.3e-25 88.4 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 Methyltransf_23 PF13489.6 OAG42670.1 - 3.5e-23 82.2 0.0 5.4e-23 81.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG42670.1 - 5.8e-12 46.2 0.0 3.7e-11 43.6 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG42670.1 - 6.6e-10 39.5 0.0 4.5e-09 36.8 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG42670.1 - 1.4e-09 37.9 0.0 0.0017 18.2 0.0 2.4 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 OAG42670.1 - 2.6e-08 34.5 0.0 1e-07 32.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_2 PF00891.18 OAG42670.1 - 0.0041 16.4 0.0 0.017 14.5 0.0 1.9 2 0 0 2 2 2 1 O-methyltransferase domain Methyltransf_4 PF02390.17 OAG42670.1 - 0.0043 16.5 0.1 0.027 14.0 0.0 2.3 2 1 1 3 3 3 1 Putative methyltransferase MTS PF05175.14 OAG42670.1 - 0.0063 16.1 0.0 0.016 14.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 OAG42670.1 - 0.015 14.6 0.0 0.032 13.5 0.0 1.5 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_16 PF10294.9 OAG42670.1 - 0.02 14.6 0.0 0.031 14.0 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase PrmA PF06325.13 OAG42670.1 - 0.025 14.0 0.0 0.037 13.4 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF938 PF06080.12 OAG42670.1 - 0.063 13.0 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Ubie_methyltran PF01209.18 OAG42670.1 - 0.083 12.2 0.0 1.8 7.9 0.0 2.2 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family GidB PF02527.15 OAG42670.1 - 0.16 11.3 0.0 2 7.7 0.0 2.2 2 0 0 2 2 2 0 rRNA small subunit methyltransferase G DUF2235 PF09994.9 OAG42671.1 - 1.6e-71 241.0 0.0 2e-71 240.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Beta_helix PF13229.6 OAG42672.1 - 1.4e-08 34.7 5.4 4.7e-06 26.5 0.6 2.2 1 1 1 2 2 2 2 Right handed beta helix region NosD PF05048.13 OAG42672.1 - 3.1e-05 23.4 0.7 0.0044 16.3 0.6 2.1 1 1 1 2 2 2 2 Periplasmic copper-binding protein (NosD) FAD_binding_3 PF01494.19 OAG42673.1 - 1e-22 80.9 1.0 1.5e-13 50.7 0.2 2.8 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 OAG42673.1 - 2.4e-05 24.5 0.0 5.7e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 OAG42673.1 - 8e-05 21.9 0.0 0.00017 20.8 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAG42673.1 - 0.00033 20.4 0.0 0.0022 17.7 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 OAG42673.1 - 0.00068 20.1 0.4 0.024 15.2 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG42673.1 - 0.001 18.4 0.1 0.0069 15.7 0.2 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAG42673.1 - 0.0011 18.3 0.0 0.016 14.5 0.0 2.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 OAG42673.1 - 0.0053 17.0 0.6 0.012 15.8 0.1 1.8 2 0 0 2 2 2 1 TrkA-N domain Lycopene_cycl PF05834.12 OAG42673.1 - 0.0081 15.2 0.1 0.012 14.7 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 OAG42673.1 - 0.074 12.3 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 OAG42673.1 - 0.078 11.7 0.1 0.34 9.6 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein Aldolase_II PF00596.21 OAG42675.1 - 8.2e-29 100.9 0.4 1.1e-28 100.4 0.4 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Acyl-CoA_dh_1 PF00441.24 OAG42677.1 - 1.4e-28 100.0 0.7 2.1e-28 99.4 0.7 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 OAG42677.1 - 1.8e-20 72.9 0.0 3e-20 72.2 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 OAG42677.1 - 1.2e-12 48.5 0.0 6.2e-12 46.2 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 OAG42677.1 - 1.2e-11 45.1 1.7 1.9e-11 44.4 1.7 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain SWIRM-assoc_3 PF16498.5 OAG42677.1 - 0.16 12.3 0.0 0.48 10.7 0.0 1.8 1 0 0 1 1 1 0 SWIRM-associated domain at the C-terminal NmrA PF05368.13 OAG42678.1 - 2.2e-20 73.2 0.1 3.1e-20 72.8 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG42678.1 - 1.8e-17 63.8 0.1 2.5e-17 63.4 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAG42678.1 - 0.0015 18.1 0.1 0.0029 17.1 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 OAG42678.1 - 0.0083 16.6 0.2 0.016 15.6 0.2 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DXP_reductoisom PF02670.16 OAG42678.1 - 0.0095 16.7 0.1 0.026 15.2 0.1 1.8 1 1 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase DapB_N PF01113.20 OAG42678.1 - 0.013 15.6 0.1 0.023 14.8 0.1 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus RmlD_sub_bind PF04321.17 OAG42678.1 - 0.077 12.1 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain OSCP PF00213.18 OAG42678.1 - 0.14 12.3 0.1 0.47 10.6 0.0 1.9 2 0 0 2 2 2 0 ATP synthase delta (OSCP) subunit 3Beta_HSD PF01073.19 OAG42678.1 - 0.18 10.7 0.2 0.38 9.7 0.2 1.6 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family 4HBT_3 PF13622.6 OAG42679.1 - 8e-42 144.2 0.2 9.7e-42 143.9 0.2 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 OAG42679.1 - 0.011 15.6 0.5 0.025 14.4 0.5 1.6 1 0 0 1 1 1 0 Acyl-CoA thioesterase Lactamase_B PF00753.27 OAG42680.1 - 6.1e-13 49.2 1.0 3.8e-12 46.6 1.0 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OAG42680.1 - 0.00073 19.1 0.0 0.0011 18.5 0.0 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 OAG42680.1 - 0.0057 16.6 0.1 0.085 12.7 0.1 2.1 1 1 0 2 2 2 1 Beta-lactamase superfamily domain TRI12 PF06609.13 OAG42681.1 - 1.4e-32 112.9 13.4 1.9e-31 109.2 13.4 2.0 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG42681.1 - 5.9e-19 68.2 24.6 1.5e-18 66.9 24.1 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Aldolase_II PF00596.21 OAG42681.1 - 2e-13 50.7 0.0 3.4e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Sugar_tr PF00083.24 OAG42681.1 - 3.3e-10 39.4 3.3 4.4e-10 39.0 3.3 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_3 PF05977.13 OAG42681.1 - 3e-06 25.9 5.8 4.3e-06 25.4 5.8 1.2 1 0 0 1 1 1 1 Transmembrane secretion effector Fungal_trans PF04082.18 OAG42682.1 - 7.4e-06 25.2 0.5 1e-05 24.7 0.2 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Iso_dh PF00180.20 OAG42683.1 - 1.2e-17 64.2 4.0 5.1e-14 52.2 1.1 2.0 1 1 1 2 2 2 2 Isocitrate/isopropylmalate dehydrogenase FAD-oxidase_C PF02913.19 OAG42685.1 - 1.1e-60 205.3 0.0 1.5e-60 204.9 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 OAG42685.1 - 4.1e-37 127.0 0.4 1.5e-36 125.2 0.3 1.9 2 0 0 2 2 2 1 FAD binding domain FMO-like PF00743.19 OAG42686.1 - 9.3e-25 87.0 0.0 2.1e-22 79.3 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OAG42686.1 - 7.3e-11 42.1 0.0 2.2e-10 40.6 0.0 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 OAG42686.1 - 2.6e-08 33.5 0.0 2.8e-07 30.1 0.0 2.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAG42686.1 - 1.4e-07 31.1 0.0 3.8e-06 26.4 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG42686.1 - 1.1e-05 24.7 0.0 0.0011 18.2 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 OAG42686.1 - 0.0042 17.1 0.3 0.058 13.4 0.0 2.7 3 0 0 3 3 3 1 FAD-NAD(P)-binding Amino_oxidase PF01593.24 OAG42686.1 - 0.0059 16.0 0.0 4.8 6.3 0.0 3.5 2 2 2 4 4 4 1 Flavin containing amine oxidoreductase Thi4 PF01946.17 OAG42686.1 - 0.14 11.4 0.0 7.8 5.7 0.0 2.3 2 0 0 2 2 2 0 Thi4 family Pro_isomerase PF00160.21 OAG42687.1 - 5.7e-36 124.2 0.0 1.1e-35 123.2 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pyr_redox_2 PF07992.14 OAG42690.1 - 5.3e-08 32.4 0.0 5.9e-05 22.4 0.0 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG42690.1 - 3.6e-06 27.1 0.1 1.8e-05 24.9 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 OAG42690.1 - 5e-06 25.9 0.1 0.0012 18.1 0.0 3.1 2 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 OAG42690.1 - 0.00032 21.2 0.6 1 10.0 0.2 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 OAG42690.1 - 0.00058 18.4 0.0 1.9 6.8 0.0 3.0 3 0 0 3 3 3 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OAG42690.1 - 0.00082 18.7 0.1 3.2 6.9 0.1 3.3 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAG42690.1 - 0.0035 17.4 0.0 0.73 9.8 0.0 2.7 2 0 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.24 OAG42690.1 - 0.0058 16.2 3.6 0.72 9.4 0.5 2.7 1 1 0 3 3 3 2 FAD dependent oxidoreductase Shikimate_DH PF01488.20 OAG42690.1 - 0.028 14.5 0.0 0.18 11.8 0.0 2.1 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 OAG42690.1 - 0.069 12.4 0.2 0.77 8.9 0.1 2.3 2 0 0 2 2 2 0 FAD binding domain TRI12 PF06609.13 OAG42691.1 - 9.8e-55 186.1 23.3 1.2e-54 185.8 23.3 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG42691.1 - 2.2e-22 79.5 49.3 2.2e-22 79.5 49.3 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.6 OAG42691.1 - 3.7e-07 29.0 1.2 3.7e-07 29.0 1.2 3.1 3 1 0 3 3 3 1 MFS/sugar transport protein Sugar_tr PF00083.24 OAG42691.1 - 7.5e-07 28.4 16.2 7.5e-07 28.4 16.2 3.7 3 2 0 3 3 3 1 Sugar (and other) transporter DUF3493 PF11998.8 OAG42691.1 - 0.7 10.1 0.0 0.7 10.1 0.0 3.4 4 0 0 4 4 4 0 Low psii accumulation1 / Rep27 4HBT_3 PF13622.6 OAG42692.1 - 5.1e-56 190.7 0.5 6.3e-56 190.4 0.5 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 OAG42692.1 - 4.6e-16 58.9 0.7 2.1e-08 34.1 0.0 4.1 3 2 1 4 4 4 3 Acyl-CoA thioesterase Fungal_trans PF04082.18 OAG42693.1 - 1.3e-17 63.7 0.1 2.2e-17 63.0 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain AA_permease PF00324.21 OAG42694.1 - 1.4e-99 333.9 37.9 1.6e-99 333.7 37.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAG42694.1 - 2.4e-26 92.6 42.1 2.9e-26 92.3 42.1 1.0 1 0 0 1 1 1 1 Amino acid permease Fungal_trans PF04082.18 OAG42695.1 - 3.2e-11 42.8 0.3 5.9e-11 41.9 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain UTP15_C PF09384.10 OAG42695.1 - 0.073 12.8 0.3 0.22 11.2 0.1 1.8 2 0 0 2 2 2 0 UTP15 C terminal Cupin_2 PF07883.11 OAG42696.1 - 9.6e-07 28.4 0.1 0.014 15.1 0.0 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_1 PF00190.22 OAG42696.1 - 0.00045 19.9 0.0 0.00072 19.2 0.0 1.3 1 0 0 1 1 1 1 Cupin ARD PF03079.14 OAG42696.1 - 0.25 11.5 0.0 0.4 10.8 0.0 1.2 1 0 0 1 1 1 0 ARD/ARD' family DAO PF01266.24 OAG42697.1 - 5.6e-33 115.0 0.0 7.1e-33 114.6 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAG42697.1 - 4.3e-07 30.1 0.1 1.8e-06 28.1 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAG42697.1 - 3.2e-05 23.3 0.0 0.096 11.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 OAG42697.1 - 0.0014 18.0 0.0 0.06 12.6 0.0 2.4 2 1 0 2 2 2 1 Flavin containing amine oxidoreductase ThiF PF00899.21 OAG42697.1 - 0.0028 17.1 0.1 0.0056 16.1 0.1 1.4 1 0 0 1 1 1 1 ThiF family ApbA PF02558.16 OAG42697.1 - 0.0039 16.8 0.0 0.0075 15.9 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.6 OAG42697.1 - 0.0098 15.2 0.0 0.021 14.1 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Glu_dehyd_C PF16912.5 OAG42697.1 - 0.012 15.1 0.0 0.021 14.3 0.0 1.3 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus FAD_binding_2 PF00890.24 OAG42697.1 - 0.035 13.2 0.0 0.057 12.5 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain FAD_binding_3 PF01494.19 OAG42697.1 - 0.062 12.5 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 OAG42697.1 - 0.17 10.5 0.0 0.4 9.3 0.0 1.6 2 0 0 2 2 2 0 HI0933-like protein Shikimate_DH PF01488.20 OAG42697.1 - 0.2 11.7 0.0 0.63 10.1 0.0 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase adh_short_C2 PF13561.6 OAG42698.1 - 1.7e-58 197.9 2.9 1.9e-58 197.8 2.9 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG42698.1 - 2.8e-43 147.7 0.4 3.3e-43 147.4 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG42698.1 - 1.4e-10 41.4 0.3 1.9e-10 41.0 0.3 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 OAG42698.1 - 0.00013 21.9 0.8 0.00034 20.5 0.2 1.8 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ad_cyc_g-alpha PF08509.11 OAG42698.1 - 0.081 12.7 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Adenylate cyclase G-alpha binding domain FMO-like PF00743.19 OAG42699.1 - 3.5e-11 42.2 0.0 6.5e-11 41.3 0.0 1.4 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OAG42699.1 - 3.2e-10 40.1 0.0 2.2e-07 31.0 0.0 2.8 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 OAG42699.1 - 1.1e-07 31.4 0.0 0.0002 20.7 0.0 2.7 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 OAG42699.1 - 6.1e-07 29.4 0.0 0.00088 19.0 0.0 2.9 1 1 1 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 OAG42699.1 - 2e-06 27.3 0.0 1e-05 25.0 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAG42699.1 - 9.1e-06 25.1 0.0 9.4e-05 21.8 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAG42699.1 - 7e-05 22.9 0.4 0.053 13.5 0.0 3.6 3 2 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.17 OAG42699.1 - 0.00025 20.4 0.0 0.0095 15.2 0.0 2.7 3 0 0 3 3 3 1 Thi4 family Shikimate_DH PF01488.20 OAG42699.1 - 0.0003 20.9 0.0 0.0012 18.9 0.0 2.0 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 OAG42699.1 - 0.016 14.6 0.0 0.033 13.6 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 OAG42699.1 - 0.036 13.2 0.0 0.093 11.8 0.0 1.7 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 OAG42699.1 - 0.041 12.9 0.0 0.079 12.0 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Semialdhyde_dh PF01118.24 OAG42699.1 - 0.049 14.1 0.0 0.35 11.3 0.0 2.3 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 OAG42701.1 - 1.9e-19 70.0 0.0 3.2e-15 56.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG42701.1 - 3.8e-15 55.9 0.0 1.8e-13 50.4 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 OAG42701.1 - 1.4e-11 43.5 0.0 3e-11 42.5 0.0 1.6 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 OAG42701.1 - 4.1e-09 36.0 0.2 1.9e-06 27.3 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.12 OAG42701.1 - 1.5e-06 27.5 0.4 0.0078 15.3 0.0 3.8 4 0 0 4 4 4 1 Lycopene cyclase protein Pyr_redox PF00070.27 OAG42701.1 - 4e-06 27.3 0.0 0.15 12.6 0.0 3.3 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 OAG42701.1 - 4.8e-05 22.8 0.4 0.00071 18.9 0.2 2.5 2 1 1 3 3 3 1 FAD binding domain NAD_binding_8 PF13450.6 OAG42701.1 - 9.5e-05 22.6 0.4 0.0013 19.0 0.0 2.9 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.20 OAG42701.1 - 0.00015 21.8 0.0 0.11 12.6 0.0 3.0 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.17 OAG42701.1 - 0.00039 19.7 0.1 0.056 12.7 0.1 3.0 3 0 0 3 3 3 1 Thi4 family DAO PF01266.24 OAG42701.1 - 0.00071 19.2 5.6 0.073 12.6 0.0 3.7 2 1 1 3 3 3 1 FAD dependent oxidoreductase F420_oxidored PF03807.17 OAG42701.1 - 0.0021 18.6 0.2 2.4 8.8 0.0 2.9 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent HI0933_like PF03486.14 OAG42701.1 - 0.0024 16.7 0.3 0.14 10.8 0.0 2.8 3 0 0 3 3 3 1 HI0933-like protein TrkA_N PF02254.18 OAG42701.1 - 0.0039 17.4 1.4 0.73 10.1 0.0 3.4 4 0 0 4 4 3 1 TrkA-N domain 3HCDH_N PF02737.18 OAG42701.1 - 0.0048 16.8 0.0 1.7 8.5 0.0 2.4 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Chon_Sulph_att PF06566.11 OAG42701.1 - 0.011 15.6 0.0 0.026 14.4 0.0 1.5 1 0 0 1 1 1 0 Chondroitin sulphate attachment domain GIDA PF01134.22 OAG42701.1 - 0.027 13.6 0.9 3.9 6.5 0.0 2.7 3 0 0 3 3 3 0 Glucose inhibited division protein A ApbA PF02558.16 OAG42701.1 - 0.032 13.9 0.0 0.41 10.3 0.0 2.5 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA NAD_binding_9 PF13454.6 OAG42701.1 - 0.078 13.0 1.1 10 6.1 0.0 3.1 3 0 0 3 3 3 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 OAG42701.1 - 0.26 10.3 3.5 0.74 8.8 0.1 3.0 3 1 0 3 3 3 0 FAD binding domain Glyco_hydro_125 PF06824.11 OAG42702.1 - 1.1e-176 587.8 0.1 1.3e-176 587.6 0.1 1.0 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) HET PF06985.11 OAG42703.1 - 3.5e-23 82.6 0.2 3.5e-15 56.6 0.1 2.8 2 0 0 2 2 2 2 Heterokaryon incompatibility protein (HET) DUF4149 PF13664.6 OAG42704.1 - 0.16 12.3 4.4 0.71 10.2 4.4 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4149) DUF4231 PF14015.6 OAG42704.1 - 0.54 10.8 5.0 0.26 11.8 0.3 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) MFS_1 PF07690.16 OAG42705.1 - 2.5e-16 59.5 48.8 1.6e-08 33.9 13.0 2.3 2 1 0 2 2 2 2 Major Facilitator Superfamily SecG PF03840.14 OAG42705.1 - 0.065 13.3 0.1 0.065 13.3 0.1 2.7 3 0 0 3 3 3 0 Preprotein translocase SecG subunit HSF_DNA-bind PF00447.17 OAG42706.1 - 9.9e-29 99.8 0.1 9.9e-29 99.8 0.1 2.0 2 0 0 2 2 2 1 HSF-type DNA-binding Golgin_A5 PF09787.9 OAG42706.1 - 0.037 13.5 4.1 0.087 12.3 4.1 1.6 1 0 0 1 1 1 0 Golgin subfamily A member 5 Ets PF00178.22 OAG42706.1 - 0.089 13.3 0.0 0.22 12.0 0.0 1.6 1 0 0 1 1 1 0 Ets-domain APG6_N PF17675.1 OAG42706.1 - 0.23 12.0 9.8 0.73 10.4 5.5 3.1 3 1 0 3 3 3 0 Apg6 coiled-coil region MbeD_MobD PF04899.12 OAG42706.1 - 0.33 11.1 5.1 11 6.2 2.9 2.7 2 0 0 2 2 2 0 MbeD/MobD like Spc7 PF08317.11 OAG42706.1 - 0.47 9.3 5.7 0.12 11.2 1.3 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein Baculo_PEP_C PF04513.12 OAG42706.1 - 1.5 8.9 6.1 2.6 8.1 2.0 2.4 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Seryl_tRNA_N PF02403.22 OAG42706.1 - 2.5 8.4 7.1 0.5 10.6 0.4 2.9 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF3450 PF11932.8 OAG42706.1 - 9.5 5.4 13.1 0.4 10.0 3.9 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3450) Aldo_ket_red PF00248.21 OAG42707.1 - 1.3e-12 47.6 0.0 6e-12 45.4 0.0 1.9 1 1 1 2 2 2 1 Aldo/keto reductase family R3H PF01424.22 OAG42708.1 - 7.9e-13 48.2 0.6 1.5e-12 47.3 0.6 1.5 1 0 0 1 1 1 1 R3H domain RRM_1 PF00076.22 OAG42708.1 - 1.4e-06 28.0 0.0 3.4e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_2 PF04059.12 OAG42708.1 - 0.045 14.0 0.0 0.075 13.3 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif 2 Histone PF00125.24 OAG42709.1 - 6.8e-17 62.1 0.0 9e-17 61.7 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 OAG42709.1 - 8.8e-13 47.8 0.1 2e-12 46.6 0.1 1.6 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 OAG42709.1 - 3.2e-05 24.1 0.0 4.9e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone UPF0047 PF01894.17 OAG42711.1 - 1e-27 96.6 0.0 2e-27 95.6 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 zf-RanBP PF00641.18 OAG42711.1 - 6.2e-08 31.8 0.8 1.4e-07 30.7 0.8 1.6 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others Utp14 PF04615.13 OAG42711.1 - 0.0085 14.7 12.4 0.33 9.5 8.8 2.5 2 0 0 2 2 2 2 Utp14 protein MPP6 PF10175.9 OAG42711.1 - 0.0095 16.4 13.9 0.0095 16.4 13.9 3.4 2 1 0 2 2 2 1 M-phase phosphoprotein 6 CutC PF03932.14 OAG42712.1 - 9.8e-63 211.3 0.0 1.2e-62 211.1 0.0 1.0 1 0 0 1 1 1 1 CutC family B12-binding PF02310.19 OAG42712.1 - 0.06 13.4 0.0 0.14 12.2 0.0 1.6 2 0 0 2 2 2 0 B12 binding domain 2H-phosphodiest PF08975.10 OAG42713.1 - 3.5e-32 110.8 0.0 5.5e-32 110.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1868) 2_5_RNA_ligase2 PF13563.6 OAG42713.1 - 0.046 13.6 0.0 0.065 13.1 0.0 1.3 1 0 0 1 1 1 0 2'-5' RNA ligase superfamily DLH PF01738.18 OAG42714.1 - 1e-15 57.9 0.0 2e-15 56.9 0.0 1.5 1 1 0 1 1 1 1 Dienelactone hydrolase family Fungal_trans PF04082.18 OAG42715.1 - 1.7e-11 43.6 0.0 2.9e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain NuA4 PF09340.10 OAG42715.1 - 0.15 12.0 0.3 0.4 10.6 0.3 1.7 1 0 0 1 1 1 0 Histone acetyltransferase subunit NuA4 HET PF06985.11 OAG42717.1 - 9.1e-27 94.2 0.0 1.8e-26 93.3 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Pkinase PF00069.25 OAG42717.1 - 2.6e-15 56.5 0.0 6.1e-15 55.3 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG42717.1 - 3.9e-09 36.2 0.0 6.3e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OAG42718.1 - 2e-07 31.2 0.2 3.1e-07 30.6 0.2 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 OAG42718.1 - 0.00018 21.1 0.1 0.00027 20.6 0.1 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.20 OAG42718.1 - 0.011 15.0 0.0 0.023 14.0 0.0 1.5 2 0 0 2 2 2 0 Ecdysteroid kinase Pkinase PF00069.25 OAG42718.1 - 0.23 10.8 0.0 6.5 6.0 0.0 2.2 2 0 0 2 2 2 0 Protein kinase domain zf-Di19 PF05605.12 OAG42720.1 - 0.0072 16.6 0.8 0.0072 16.6 0.8 3.2 2 1 2 4 4 4 1 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 OAG42720.1 - 0.14 12.6 2.2 0.21 12.1 0.0 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type DUF3435 PF11917.8 OAG42721.1 - 4.2e-20 72.1 0.4 7.2e-20 71.3 0.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) LprI PF07007.12 OAG42721.1 - 0.014 16.0 3.2 0.2 12.3 1.3 2.6 2 0 0 2 2 2 0 Lysozyme inhibitor LprI Poxvirus_B22R PF04395.12 OAG42721.1 - 0.11 12.0 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Poxvirus B22R protein DUF4267 PF14087.6 OAG42722.1 - 1.7e-18 66.7 3.8 2e-18 66.5 3.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) bZIP_1 PF00170.21 OAG42723.1 - 0.0093 16.0 8.1 0.0093 16.0 8.1 2.2 1 1 1 2 2 2 1 bZIP transcription factor DDE_Tnp_IS66 PF03050.14 OAG42723.1 - 0.043 13.3 3.7 0.057 12.9 3.7 1.1 1 0 0 1 1 1 0 Transposase IS66 family Csm2_III-A PF03750.13 OAG42723.1 - 0.087 13.7 1.7 0.18 12.7 1.7 1.6 1 1 0 1 1 1 0 Csm2 Type III-A Alfin PF12165.8 OAG42723.1 - 0.16 11.6 0.2 0.26 10.9 0.2 1.3 1 0 0 1 1 1 0 Alfin DUF2205 PF10224.9 OAG42723.1 - 1.1 9.3 5.6 2.1 8.4 5.6 1.5 1 0 0 1 1 1 0 Short coiled-coil protein Cu-oxidase_2 PF07731.14 OAG42725.1 - 1.8e-39 134.6 6.0 7.3e-38 129.4 0.1 3.5 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 OAG42725.1 - 1.1e-35 122.2 9.7 2.3e-34 118.0 0.9 4.4 4 1 1 5 5 5 2 Multicopper oxidase Cu-oxidase PF00394.22 OAG42725.1 - 8.6e-26 90.9 3.3 1.1e-25 90.7 0.1 2.5 3 0 0 3 3 3 1 Multicopper oxidase MFS_1 PF07690.16 OAG42726.1 - 3.1e-40 138.2 59.0 2.5e-39 135.2 59.0 2.7 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 OAG42726.1 - 2.1e-09 36.4 16.4 2.7e-09 36.0 16.4 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) zf-CHCC PF10276.9 OAG42727.1 - 9.7e-16 57.5 2.9 1.5e-15 56.9 2.9 1.3 1 0 0 1 1 1 1 Zinc-finger domain Proteasome PF00227.26 OAG42728.1 - 1.9e-50 171.0 0.5 1.5e-41 142.0 0.1 2.1 1 1 1 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.9 OAG42728.1 - 9e-13 47.6 0.2 2.3e-12 46.4 0.1 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature PhyH PF05721.13 OAG42729.1 - 8.3e-19 68.7 0.0 1.2e-18 68.2 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 OAG42729.1 - 0.21 10.3 0.0 0.29 9.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1479) NAD-GH PF10712.9 OAG42729.1 - 0.25 9.8 0.0 0.33 9.4 0.0 1.1 1 0 0 1 1 1 0 NAD-specific glutamate dehydrogenase Amidase PF01425.21 OAG42730.1 - 2.9e-98 329.8 0.0 3.6e-98 329.5 0.0 1.1 1 0 0 1 1 1 1 Amidase MFS_1 PF07690.16 OAG42731.1 - 2.4e-07 30.0 34.4 0.0006 18.8 32.5 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.16 OAG42731.1 - 2.4e-07 30.6 6.7 2.4e-07 30.6 6.7 2.2 2 1 0 2 2 2 1 Ion channel regulatory protein UNC-93 DUF2755 PF10954.8 OAG42731.1 - 0.073 13.0 0.3 10 6.1 0.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2755) LAB_N PF07578.11 OAG42731.1 - 0.24 11.5 4.8 0.24 11.5 2.4 2.3 2 0 0 2 2 2 0 Lipid A Biosynthesis N-terminal domain Fungal_trans_2 PF11951.8 OAG42732.1 - 4.9e-25 88.1 0.3 3.2e-16 59.1 0.1 2.1 1 1 1 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG42732.1 - 0.0005 20.1 3.8 0.00093 19.3 3.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HEAT PF02985.22 OAG42732.1 - 0.16 12.3 0.1 5.1 7.6 0.0 2.8 2 0 0 2 2 2 0 HEAT repeat SAT PF16073.5 OAG42733.1 - 4e-72 242.8 0.7 4e-72 242.8 0.7 2.6 3 0 0 3 3 3 1 Starter unit:ACP transacylase in aflatoxin biosynthesis ketoacyl-synt PF00109.26 OAG42733.1 - 4.8e-72 242.6 0.0 8.9e-72 241.7 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 OAG42733.1 - 2.4e-37 129.1 0.0 4.7e-37 128.2 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 OAG42733.1 - 2.4e-35 121.1 0.0 8.4e-35 119.3 0.0 2.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.25 OAG42733.1 - 7e-23 80.8 6.3 1.1e-12 48.1 0.5 2.6 2 0 0 2 2 2 2 Phosphopantetheine attachment site Thioesterase PF00975.20 OAG42733.1 - 4.7e-19 69.4 0.0 2.5e-18 67.0 0.0 2.3 2 0 0 2 2 2 1 Thioesterase domain PS-DH PF14765.6 OAG42733.1 - 2.4e-13 50.0 0.0 7.5e-13 48.4 0.0 1.8 2 0 0 2 2 2 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 OAG42733.1 - 7.1e-08 32.9 0.0 2e-07 31.4 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Abhydrolase_6 PF12697.7 OAG42733.1 - 3.4e-05 24.5 0.2 0.016 15.9 0.0 3.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Thiolase_N PF00108.23 OAG42733.1 - 0.0079 15.6 0.0 0.022 14.1 0.0 1.7 1 0 0 1 1 1 1 Thiolase, N-terminal domain OrfB_Zn_ribbon PF07282.11 OAG42734.1 - 0.017 15.0 1.6 0.017 15.0 1.6 2.1 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Blt1 PF12754.7 OAG42735.1 - 1.7e-33 116.1 3.2 4.7e-31 108.1 3.3 2.8 2 1 0 2 2 2 1 Blt1 N-terminal domain Blt1_C PF17183.4 OAG42735.1 - 1.6e-15 56.4 0.1 2.6e-15 55.8 0.1 1.3 1 0 0 1 1 1 1 Get5 carboxyl domain SMP PF04927.12 OAG42735.1 - 0.29 11.6 3.0 0.16 12.4 0.8 1.7 2 0 0 2 2 2 0 Seed maturation protein His_Phos_2 PF00328.22 OAG42736.1 - 4.2e-35 121.8 0.0 6e-35 121.3 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) LPMO_10 PF03067.15 OAG42737.1 - 0.24 12.0 2.6 1.8 9.2 2.6 2.4 1 1 0 1 1 1 0 Lytic polysaccharide mono-oxygenase, cellulose-degrading 4HBT_2 PF13279.6 OAG42738.1 - 2.4e-09 37.8 0.0 4.7e-09 36.8 0.0 1.5 2 0 0 2 2 2 1 Thioesterase-like superfamily HIG_1_N PF04588.13 OAG42739.1 - 4e-05 23.8 0.9 4e-05 23.8 0.9 1.7 2 0 0 2 2 2 1 Hypoxia induced protein conserved region DUF2448 PF10476.9 OAG42739.1 - 0.13 12.1 0.0 0.27 11.1 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function C-terminus (DUF2448) Romo1 PF10247.9 OAG42739.1 - 0.15 12.4 6.1 1.4 9.4 1.3 2.9 3 1 0 3 3 3 0 Reactive mitochondrial oxygen species modulator 1 Med26 PF08711.11 OAG42740.1 - 1.3e-13 50.7 0.0 2.5e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 TFIIS helical bundle-like domain zf_C2H2_10 PF18414.1 OAG42740.1 - 0.21 11.2 0.0 0.43 10.2 0.0 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger MFS_1 PF07690.16 OAG42741.1 - 1.9e-24 86.3 31.1 1.9e-24 86.3 31.1 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily Trp_oprn_chp PF09534.10 OAG42741.1 - 0.48 10.2 12.7 3.1 7.5 0.0 4.2 3 1 1 4 4 4 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Nup54 PF13874.6 OAG42742.1 - 6.9e-35 120.2 3.4 6.9e-35 120.2 3.4 2.3 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.6 OAG42742.1 - 1.1e-14 55.0 126.2 2.2e-08 34.8 33.8 3.2 1 1 2 3 3 3 3 Nucleoporin FG repeat region Nup54_57_C PF18570.1 OAG42742.1 - 1.5e-07 30.9 3.1 1.5e-07 30.9 3.1 2.0 2 0 0 2 2 2 1 NUP57/Nup54 C-terminal domain Prominin PF05478.11 OAG42742.1 - 0.4 8.6 5.8 0.55 8.1 5.8 1.1 1 0 0 1 1 1 0 Prominin FapA PF03961.13 OAG42742.1 - 1.9 7.0 8.8 0.67 8.5 4.3 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A HAUS-augmin3 PF14932.6 OAG42742.1 - 2.5 7.6 14.6 0.065 12.8 2.6 2.3 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 GATase_2 PF00310.21 OAG42743.1 - 2.5e-178 593.1 0.0 3.6e-178 592.6 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 OAG42743.1 - 1.6e-155 517.8 0.0 3.1e-155 516.8 0.0 1.5 2 0 0 2 2 2 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 OAG42743.1 - 1.5e-103 346.1 0.0 4e-102 341.5 0.0 2.5 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 OAG42743.1 - 9.7e-87 289.5 4.5 1.6e-86 288.8 4.5 1.4 1 0 0 1 1 1 1 GXGXG motif Pyr_redox_2 PF07992.14 OAG42743.1 - 1e-26 93.9 0.0 8.9e-26 90.8 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 OAG42743.1 - 6.8e-21 74.1 0.0 1.5e-20 73.1 0.0 1.6 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster NAD_binding_8 PF13450.6 OAG42743.1 - 1.3e-07 31.7 0.1 4.4e-07 30.0 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAG42743.1 - 1.2e-06 28.3 0.7 0.0053 16.4 0.2 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase Amino_oxidase PF01593.24 OAG42743.1 - 4.3e-06 26.3 0.0 7.7e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 OAG42743.1 - 5e-06 27.0 0.0 0.0027 18.2 0.1 2.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG42743.1 - 1.7e-05 24.2 0.2 0.12 11.6 0.0 3.6 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAG42743.1 - 4.7e-05 22.3 0.2 0.0001 21.1 0.2 1.5 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 OAG42743.1 - 8.1e-05 21.9 0.1 0.00036 19.8 0.1 2.0 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 OAG42743.1 - 9.3e-05 21.9 0.1 0.00018 21.0 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 OAG42743.1 - 0.00034 20.0 0.5 0.0039 16.5 0.1 2.3 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 OAG42743.1 - 0.00067 19.0 0.0 0.04 13.2 0.0 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 OAG42743.1 - 0.0042 17.5 1.2 3.2 8.3 0.1 3.0 3 0 0 3 3 2 1 Putative NAD(P)-binding GIDA PF01134.22 OAG42743.1 - 0.019 14.1 1.4 0.038 13.1 0.1 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A Thi4 PF01946.17 OAG42743.1 - 0.032 13.5 0.4 0.14 11.4 0.1 2.1 2 0 0 2 2 2 0 Thi4 family Lycopene_cycl PF05834.12 OAG42743.1 - 0.051 12.6 0.2 0.26 10.3 0.1 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein 2-Hacid_dh_C PF02826.19 OAG42743.1 - 0.072 12.5 0.0 0.2 11.0 0.0 1.7 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FMN_dh PF01070.18 OAG42743.1 - 0.072 12.1 0.9 0.31 10.0 0.9 1.9 2 0 0 2 2 2 0 FMN-dependent dehydrogenase FMO-like PF00743.19 OAG42743.1 - 0.13 10.7 0.1 1 7.7 0.0 2.3 3 0 0 3 3 3 0 Flavin-binding monooxygenase-like Apc15p PF05841.11 OAG42744.1 - 7.1e-06 26.8 1.2 1.4e-05 25.9 0.0 2.2 2 0 0 2 2 2 1 Apc15p protein ArsR PF09824.9 OAG42745.1 - 0.12 11.9 0.0 0.16 11.5 0.0 1.1 1 0 0 1 1 1 0 ArsR transcriptional regulator Pro_racemase PF05544.11 OAG42746.1 - 7.3e-61 206.0 0.0 9.7e-61 205.6 0.0 1.2 1 0 0 1 1 1 1 Proline racemase ANAPC8 PF04049.13 OAG42747.1 - 2.2e-52 176.8 0.1 3.2e-51 173.1 0.0 2.5 2 0 0 2 2 2 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_1 PF00515.28 OAG42747.1 - 3.1e-20 71.1 5.5 0.00026 20.7 0.0 6.9 7 1 0 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.6 OAG42747.1 - 7.9e-17 60.0 14.7 1.5e-05 24.9 0.0 8.8 11 0 0 11 11 11 3 Tetratricopeptide repeat TPR_14 PF13428.6 OAG42747.1 - 9.9e-17 60.2 14.8 0.0029 18.3 0.1 8.1 7 1 1 8 8 8 5 Tetratricopeptide repeat TPR_2 PF07719.17 OAG42747.1 - 4.3e-15 54.5 15.7 0.031 14.4 0.0 8.7 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_11 PF13414.6 OAG42747.1 - 3e-11 42.8 1.9 8e-07 28.6 0.6 4.4 3 2 1 4 4 4 1 TPR repeat TPR_19 PF14559.6 OAG42747.1 - 4.2e-09 36.8 12.7 0.072 13.6 0.4 6.6 5 2 0 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 OAG42747.1 - 6.2e-09 36.4 10.4 1.5e-05 25.5 0.0 5.7 5 0 0 5 5 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 OAG42747.1 - 1.7e-08 34.6 12.6 0.083 13.1 0.3 6.5 6 0 0 6 6 6 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 OAG42747.1 - 1.1e-07 32.1 12.2 0.42 10.9 0.3 6.5 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_6 PF13174.6 OAG42747.1 - 1.2e-07 31.9 16.4 6.2 7.7 0.1 8.8 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_17 PF13431.6 OAG42747.1 - 1e-05 25.6 11.3 1.7 9.2 0.0 7.3 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_9 PF13371.6 OAG42747.1 - 0.00015 21.8 10.9 0.008 16.3 0.1 5.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 OAG42747.1 - 0.00096 19.0 13.8 3.5 7.9 0.0 6.1 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_15 PF13429.6 OAG42747.1 - 0.01 15.1 6.5 0.024 13.8 0.2 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat ChAPs PF09295.10 OAG42747.1 - 0.011 14.8 0.1 10 5.0 0.0 3.2 2 1 1 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_4 PF07721.14 OAG42747.1 - 0.16 12.7 3.2 0.15 12.7 0.7 2.4 2 0 0 2 2 1 0 Tetratricopeptide repeat TPR_10 PF13374.6 OAG42747.1 - 0.22 11.4 6.2 28 4.7 0.0 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat PPR PF01535.20 OAG42747.1 - 0.29 11.5 2.6 42 4.7 0.0 3.8 4 0 0 4 4 4 0 PPR repeat RRP14 PF15459.6 OAG42747.1 - 0.51 11.0 2.2 8.4 7.1 0.0 2.8 2 0 0 2 2 2 0 60S ribosome biogenesis protein Rrp14 adh_short_C2 PF13561.6 OAG42750.1 - 4.3e-43 147.5 0.0 9.4e-43 146.4 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG42750.1 - 6e-34 117.2 0.0 1.1e-33 116.3 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase Ribosomal_L31e PF01198.19 OAG42750.1 - 0.018 15.3 0.0 0.034 14.4 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L31e Questin_oxidase PF14027.6 OAG42751.1 - 5.2e-107 358.3 1.1 6.2e-107 358.1 1.1 1.1 1 0 0 1 1 1 1 Questin oxidase-like MPM1 PF17234.2 OAG42752.1 - 0.3 11.3 12.0 0.095 13.0 0.6 2.9 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 DUF2407_C PF13373.6 OAG42752.1 - 2 8.6 5.8 5.6 7.1 5.8 1.7 1 0 0 1 1 1 0 DUF2407 C-terminal domain Fungal_trans_2 PF11951.8 OAG42754.1 - 2.4e-13 49.7 0.9 9.1e-13 47.8 0.3 2.0 2 1 0 2 2 2 1 Fungal specific transcription factor domain DUF1221 PF06760.11 OAG42754.1 - 0.029 13.9 0.0 0.053 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1221) BSD PF03909.17 OAG42754.1 - 0.12 12.4 0.0 0.29 11.2 0.0 1.6 1 0 0 1 1 1 0 BSD domain MFS_1 PF07690.16 OAG42755.1 - 3.8e-14 52.4 114.2 3.1e-09 36.2 52.5 2.9 1 1 2 3 3 3 3 Major Facilitator Superfamily FAD_binding_3 PF01494.19 OAG42756.1 - 1.6e-10 40.8 0.1 4.4e-10 39.3 0.1 1.8 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 OAG42756.1 - 0.0016 17.8 0.7 0.0051 16.1 0.6 1.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAG42756.1 - 0.0018 17.6 0.1 0.0029 16.9 0.1 1.2 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 OAG42756.1 - 0.0024 17.0 0.1 0.0054 15.8 0.1 1.6 1 1 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.14 OAG42756.1 - 0.0088 14.8 1.5 0.02 13.6 0.5 2.1 3 0 0 3 3 3 1 HI0933-like protein NAD_binding_8 PF13450.6 OAG42756.1 - 0.02 15.1 0.1 0.02 15.1 0.1 2.3 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAG42756.1 - 0.033 13.8 2.0 0.076 12.6 2.0 1.6 1 0 0 1 1 1 0 FAD dependent oxidoreductase Trp_halogenase PF04820.14 OAG42756.1 - 0.034 13.0 3.5 3.4 6.4 0.7 2.8 2 1 0 3 3 3 0 Tryptophan halogenase Pyr_redox_3 PF13738.6 OAG42756.1 - 0.088 12.1 0.7 0.13 11.5 0.7 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 OAG42756.1 - 0.089 12.1 1.2 0.092 12.0 0.0 1.5 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 OAG42756.1 - 0.093 11.8 1.4 0.14 11.2 1.4 1.2 1 0 0 1 1 1 0 FAD binding domain SQHop_cyclase_C PF13243.6 OAG42757.1 - 7.6e-56 189.5 0.1 8.1e-52 176.3 0.4 2.1 2 0 0 2 2 2 2 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 OAG42757.1 - 8.3e-42 143.3 5.1 1.9e-35 122.4 0.2 3.7 3 1 2 5 5 5 4 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.21 OAG42757.1 - 4.5e-36 122.3 2.0 7.7e-12 44.8 0.2 4.2 4 0 0 4 4 4 3 Prenyltransferase and squalene oxidase repeat TED_complement PF07678.14 OAG42757.1 - 0.00012 21.3 0.2 0.0028 16.8 0.1 2.9 2 1 1 3 3 3 1 A-macroglobulin TED domain TP6A_N PF04406.14 OAG42758.1 - 1.9e-05 24.6 0.0 4.7e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 Type IIB DNA topoisomerase UQ_con PF00179.26 OAG42759.1 - 1.2e-50 170.8 0.0 1.4e-50 170.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme NmrA PF05368.13 OAG42760.1 - 1.1e-06 28.3 0.1 1.7e-06 27.8 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG42760.1 - 0.013 15.4 0.2 0.018 14.9 0.2 1.2 1 0 0 1 1 1 0 NAD(P)H-binding adh_short_C2 PF13561.6 OAG42761.1 - 8.4e-49 166.2 0.0 1e-48 165.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG42761.1 - 6.5e-44 149.7 0.1 8.8e-44 149.3 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG42761.1 - 7.8e-09 35.7 0.0 2e-08 34.3 0.0 1.8 1 1 0 1 1 1 1 KR domain LDcluster4 PF18306.1 OAG42761.1 - 0.044 13.4 0.0 0.072 12.7 0.0 1.3 1 0 0 1 1 1 0 SLOG cluster4 family Methyltransf_25 PF13649.6 OAG42761.1 - 0.11 13.2 0.0 0.22 12.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Cyclase PF04199.13 OAG42762.1 - 3.3e-10 40.3 0.0 6.4e-10 39.4 0.0 1.4 1 1 0 1 1 1 1 Putative cyclase Fungal_trans PF04082.18 OAG42763.1 - 6e-20 71.4 0.1 9.7e-20 70.7 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG42763.1 - 3.6e-06 27.0 6.5 7e-06 26.1 6.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_N PF08240.12 OAG42764.1 - 5.7e-30 103.4 0.8 9.9e-30 102.6 0.3 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG42764.1 - 2.4e-17 63.1 0.1 4e-17 62.4 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 OAG42764.1 - 2.3e-10 40.3 0.3 0.00019 21.0 0.1 2.4 2 1 0 2 2 2 2 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 OAG42764.1 - 1.5e-05 26.1 0.0 3.3e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pyr_redox_2 PF07992.14 OAG42764.1 - 0.00049 19.4 0.1 0.025 13.8 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAG42764.1 - 0.0055 17.2 0.3 6 7.5 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 OAG42764.1 - 0.0057 16.0 0.1 0.027 13.8 0.1 1.9 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 OAG42764.1 - 0.024 14.2 0.0 0.043 13.4 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ThiF PF00899.21 OAG42764.1 - 0.031 13.6 0.3 0.061 12.7 0.3 1.4 1 0 0 1 1 1 0 ThiF family 3HCDH_N PF02737.18 OAG42764.1 - 0.037 13.9 0.0 0.068 13.0 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 OAG42764.1 - 0.1 11.9 0.1 0.15 11.3 0.1 1.1 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 OAG42764.1 - 0.16 11.2 0.0 2.1 7.5 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 OAG42765.1 - 3.4e-13 48.9 0.1 7.1e-12 44.5 0.1 2.2 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OAG42765.1 - 1.4e-07 31.1 1.5 1e-06 28.2 0.4 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG42765.1 - 2e-07 30.5 4.4 2.2e-06 27.1 0.1 2.9 3 1 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 OAG42765.1 - 4.3e-06 26.2 0.0 0.00024 20.4 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG42765.1 - 4.6e-06 26.8 0.1 1.3e-05 25.3 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Transketolase_N PF00456.21 OAG42766.1 - 9.2e-103 343.7 0.0 1.3e-102 343.2 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 OAG42766.1 - 2.6e-34 118.5 0.1 6.7e-34 117.1 0.1 1.6 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 OAG42766.1 - 3e-09 36.8 0.1 6.8e-09 35.7 0.0 1.7 2 0 0 2 2 2 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 OAG42766.1 - 8.4e-06 25.2 0.0 0.01 15.1 0.1 2.2 2 0 0 2 2 2 2 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_N PF02776.18 OAG42766.1 - 0.018 14.7 0.7 0.25 11.0 0.1 2.7 3 0 0 3 3 3 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain E1_dh PF00676.20 OAG42766.1 - 0.031 13.2 0.0 0.048 12.6 0.0 1.3 1 0 0 1 1 1 0 Dehydrogenase E1 component Sugar_tr PF00083.24 OAG42767.1 - 1.4e-92 311.0 29.6 1.7e-92 310.7 29.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG42767.1 - 2.1e-24 86.1 29.7 2.1e-24 86.1 29.7 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF971 PF06155.12 OAG42767.1 - 0.21 12.2 0.0 0.34 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF971) FtsA PF14450.6 OAG42768.1 - 0.062 13.7 0.0 0.17 12.3 0.0 1.7 1 0 0 1 1 1 0 Cell division protein FtsA FUSC PF04632.12 OAG42769.1 - 0.018 13.6 1.6 0.018 13.6 0.6 1.4 1 1 0 1 1 1 0 Fusaric acid resistance protein family HAP1_N PF04849.13 OAG42769.1 - 0.06 12.5 4.4 0.017 14.3 1.5 1.5 2 0 0 2 2 2 0 HAP1 N-terminal conserved region JIP_LZII PF16471.5 OAG42769.1 - 0.11 12.6 0.8 0.27 11.4 0.8 1.6 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II HET PF06985.11 OAG42770.1 - 5.5e-14 52.7 7.8 4.7e-12 46.5 1.9 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.16 OAG42771.1 - 1.6e-31 109.5 34.1 1.6e-31 109.5 34.1 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_M18 PF02127.15 OAG42773.1 - 7.7e-120 400.6 0.0 9.5e-120 400.3 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) adh_short PF00106.25 OAG42774.1 - 7.5e-31 107.1 0.0 2.3e-30 105.5 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG42774.1 - 7.2e-22 78.1 0.0 2e-21 76.6 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Pyr_redox_2 PF07992.14 OAG42775.1 - 5.9e-10 38.8 0.0 2.1e-06 27.2 0.0 3.1 2 2 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 OAG42775.1 - 1.2e-06 27.2 0.0 2.1e-05 23.2 0.0 2.3 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 OAG42775.1 - 0.00025 20.3 0.0 0.0021 17.2 0.0 2.0 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 OAG42775.1 - 0.00037 20.7 0.3 0.0048 17.1 0.0 2.7 2 1 1 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 OAG42775.1 - 0.0074 15.6 0.0 0.05 12.9 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAG42775.1 - 0.01 15.8 0.0 1.1 9.2 0.0 2.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding tRNA_int_endo PF01974.17 OAG42775.1 - 0.018 15.1 1.3 0.91 9.6 0.5 3.4 3 2 0 3 3 3 0 tRNA intron endonuclease, catalytic C-terminal domain Shikimate_DH PF01488.20 OAG42775.1 - 0.031 14.3 0.0 0.29 11.2 0.0 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase TRI12 PF06609.13 OAG42776.1 - 7.8e-70 235.9 22.6 1e-69 235.6 22.6 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG42776.1 - 5.9e-21 74.8 49.6 5.9e-21 74.8 49.6 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily RHD3 PF05879.12 OAG42777.1 - 0 1045.8 0.0 0 1045.5 0.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.19 OAG42777.1 - 1.7e-06 27.5 0.2 2.9e-06 26.8 0.2 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.23 OAG42777.1 - 1.8e-06 28.1 0.1 6.4e-06 26.3 0.0 1.9 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 OAG42777.1 - 2.6e-05 24.3 0.0 5.6e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.6 OAG42777.1 - 0.00015 22.1 0.0 0.00046 20.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain Septin PF00735.18 OAG42777.1 - 0.012 14.9 0.1 0.021 14.1 0.1 1.3 1 0 0 1 1 1 0 Septin AAA_16 PF13191.6 OAG42777.1 - 0.12 12.7 0.1 1.4 9.2 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain Elf1 PF05129.13 OAG42778.1 - 0.45 10.6 3.5 0.84 9.7 3.5 1.4 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like CHCH PF06747.13 OAG42779.1 - 8.4e-10 38.5 6.8 2.8e-07 30.5 2.3 2.4 2 0 0 2 2 2 2 CHCH domain CX9C PF16860.5 OAG42779.1 - 8e-05 22.6 4.4 0.0018 18.2 1.4 2.2 2 0 0 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Cmc1 PF08583.10 OAG42779.1 - 0.033 14.2 9.1 0.59 10.2 2.7 2.2 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like DnaT PF17948.1 OAG42779.1 - 0.13 12.0 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 DnaT DNA-binding domain Pet191_N PF10203.9 OAG42779.1 - 0.15 12.4 7.4 1.5 9.2 0.9 2.9 2 1 1 3 3 3 0 Cytochrome c oxidase assembly protein PET191 UCR_hinge PF02320.16 OAG42779.1 - 1.6 9.0 7.4 4.6 7.5 4.9 2.5 1 1 1 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein p450 PF00067.22 OAG42780.1 - 1.2e-69 235.3 0.0 1.5e-69 234.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_4 PF01565.23 OAG42782.1 - 3.3e-29 101.4 0.0 5.5e-29 100.7 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.19 OAG42782.1 - 2.7e-09 37.1 0.5 4.7e-09 36.2 0.5 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain Cytokin-bind PF09265.10 OAG42782.1 - 0.16 11.3 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding FAD_binding_4 PF01565.23 OAG42783.1 - 2.9e-21 75.7 0.0 4.6e-21 75.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain E1-E2_ATPase PF00122.20 OAG42784.1 - 7e-43 146.3 1.4 7e-43 146.3 1.4 3.3 4 0 0 4 4 4 1 E1-E2 ATPase MFS_1 PF07690.16 OAG42784.1 - 3.4e-32 111.8 21.1 3.4e-32 111.8 21.1 4.4 3 1 1 4 4 4 2 Major Facilitator Superfamily Hydrolase PF00702.26 OAG42784.1 - 1.4e-23 84.3 0.1 2.4e-23 83.5 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 OAG42784.1 - 1.2e-10 41.7 0.0 6.5e-10 39.3 0.0 2.3 2 0 0 2 2 2 1 Heavy-metal-associated domain HAD PF12710.7 OAG42784.1 - 0.12 12.7 0.0 0.27 11.6 0.0 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 OAG42784.1 - 0.19 11.4 0.1 13 5.4 0.0 2.3 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Acetate_kinase PF00871.17 OAG42786.1 - 2.5e-96 322.7 0.0 3e-96 322.5 0.0 1.0 1 0 0 1 1 1 1 Acetokinase family DUF1786 PF08735.10 OAG42786.1 - 0.08 12.2 0.0 0.64 9.3 0.0 2.2 3 0 0 3 3 3 0 Putative pyruvate format-lyase activating enzyme (DUF1786) Abhydrolase_6 PF12697.7 OAG42787.1 - 1.9e-07 31.9 0.4 3.1e-07 31.2 0.4 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAG42787.1 - 0.0028 17.3 0.3 0.0065 16.1 0.2 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAG42787.1 - 0.033 13.5 0.0 0.1 11.8 0.0 1.7 1 1 0 1 1 1 0 Serine aminopeptidase, S33 DUF3775 PF12616.8 OAG42788.1 - 0.8 9.8 2.3 8.6 6.5 2.3 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3775) DUF3425 PF11905.8 OAG42789.1 - 1.1e-17 64.2 1.7 1.1e-17 64.2 0.2 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3425) ATP11 PF06644.11 OAG42789.1 - 0.44 10.3 3.0 0.61 9.8 3.0 1.2 1 0 0 1 1 1 0 ATP11 protein MAS20 PF02064.15 OAG42789.1 - 2.3 8.3 5.3 3.8 7.6 5.3 1.3 1 0 0 1 1 1 0 MAS20 protein import receptor HET PF06985.11 OAG42790.1 - 0.0019 18.5 0.6 0.0054 17.1 0.1 2.0 1 1 1 2 2 2 1 Heterokaryon incompatibility protein (HET) DUF1398 PF07166.11 OAG42791.1 - 5e-07 29.8 0.0 0.00011 22.3 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF1398) Alk_phosphatase PF00245.20 OAG42792.1 - 1.7e-73 248.0 0.3 1.7e-72 244.7 0.3 1.9 1 1 0 1 1 1 1 Alkaline phosphatase Sulfatase PF00884.23 OAG42792.1 - 3.2e-08 33.3 0.1 9.6e-08 31.8 0.1 1.7 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 OAG42792.1 - 3.5e-05 23.6 0.0 5.9e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 OAG42792.1 - 0.0066 15.1 0.3 0.0097 14.6 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Metalloenzyme PF01676.18 OAG42792.1 - 0.06 12.7 0.1 0.083 12.2 0.1 1.5 1 1 0 1 1 1 0 Metalloenzyme superfamily Rubredoxin_2 PF18073.1 OAG42792.1 - 0.24 11.1 0.9 0.44 10.3 0.9 1.4 1 0 0 1 1 1 0 Rubredoxin metal binding domain Glyco_hydro_43 PF04616.14 OAG42793.1 - 1.2e-22 80.6 0.1 1.6e-22 80.2 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.20 OAG42793.1 - 0.016 14.8 0.0 0.12 11.9 0.0 2.1 1 1 1 2 2 2 0 Glycosyl hydrolases family 32 N-terminal domain BA14K PF07886.11 OAG42793.1 - 0.11 12.4 0.2 17 5.4 0.0 2.6 2 0 0 2 2 2 0 BA14K-like protein XRCC4 PF06632.12 OAG42795.1 - 4.2e-12 45.6 17.8 9.7e-12 44.4 17.8 1.5 1 1 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 FAM76 PF16046.5 OAG42795.1 - 0.0065 15.9 8.0 0.0065 15.9 8.0 1.9 2 0 0 2 2 2 1 FAM76 protein DUF4317 PF14199.6 OAG42795.1 - 0.019 14.2 8.3 1.1 8.3 0.0 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4317) CC2-LZ PF16516.5 OAG42795.1 - 0.27 11.6 9.0 0.11 12.8 5.2 2.2 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator TMPIT PF07851.13 OAG42795.1 - 0.4 9.9 2.9 0.64 9.2 2.9 1.3 1 0 0 1 1 1 0 TMPIT-like protein NPV_P10 PF05531.12 OAG42795.1 - 1.3 9.5 8.3 1.5 9.3 4.7 2.5 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF2730 PF10805.8 OAG42795.1 - 2.9 8.0 6.9 4.3 7.5 0.6 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF2730) CCDC-167 PF15188.6 OAG42795.1 - 9.6 6.6 10.9 0.37 11.2 2.6 2.8 2 1 1 3 3 3 0 Coiled-coil domain-containing protein 167 DUF3759 PF12585.8 OAG42796.1 - 2e-40 136.7 7.2 2.5e-40 136.4 7.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) Abhydrolase_2 PF02230.16 OAG42797.1 - 2.4e-14 53.7 0.0 3e-14 53.3 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Esterase PF00756.20 OAG42797.1 - 0.014 15.1 0.0 0.021 14.5 0.0 1.5 1 1 0 1 1 1 0 Putative esterase GCP_N_terminal PF17681.1 OAG42799.1 - 1.4e-28 100.5 0.0 3.1e-28 99.3 0.0 1.6 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 OAG42799.1 - 5.5e-22 78.6 4.7 9.2e-22 77.9 4.7 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP5-Mod21 PF14609.6 OAG42799.1 - 2.2e-06 26.4 1.5 2.4e-05 22.9 0.3 2.6 2 1 0 2 2 2 1 gamma-Tubulin ring complex non-core subunit mod21 ACDC PF14733.6 OAG42799.1 - 0.17 12.2 0.4 1.1 9.7 0.1 2.6 2 0 0 2 2 2 0 AP2-coincident C-terminal Voldacs PF03517.13 OAG42800.1 - 8.1e-27 94.0 2.1 1.1e-26 93.6 0.0 2.0 2 0 0 2 2 2 1 Regulator of volume decrease after cellular swelling EFTUD2 PF16004.5 OAG42800.1 - 1.2 9.7 5.0 0.51 10.9 2.0 2.0 2 0 0 2 2 2 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus Glyco_transf_15 PF01793.16 OAG42801.1 - 4.2e-111 371.3 9.0 5.1e-111 371.0 9.0 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase MFS_1 PF07690.16 OAG42802.1 - 5.9e-23 81.4 31.5 1.1e-22 80.4 30.6 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily COX5A PF02284.16 OAG42803.1 - 7.6e-41 138.3 0.3 1e-40 137.9 0.3 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va LTV PF04180.14 OAG42803.1 - 0.041 13.6 0.0 0.042 13.6 0.0 1.2 1 0 0 1 1 1 0 Low temperature viability protein DUF4972 PF16342.5 OAG42803.1 - 0.13 12.0 0.1 0.24 11.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4972) ELO PF01151.18 OAG42804.1 - 5.4e-63 212.8 22.7 6.8e-63 212.5 22.7 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family GATase_5 PF13507.6 OAG42805.1 - 1.5e-89 299.6 0.0 3e-89 298.6 0.0 1.5 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 OAG42805.1 - 3.5e-41 140.9 0.0 4.7e-28 98.3 0.1 2.4 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 OAG42805.1 - 2.5e-35 120.9 0.0 5.6e-35 119.8 0.0 1.6 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 OAG42805.1 - 4.5e-21 75.1 0.0 1e-20 74.0 0.0 1.7 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain AIRS PF00586.24 OAG42805.1 - 0.049 14.3 0.1 0.33 11.6 0.0 2.4 2 0 0 2 2 2 0 AIR synthase related protein, N-terminal domain Sugar_tr PF00083.24 OAG42806.1 - 1.6e-99 333.9 16.2 2.3e-99 333.3 16.2 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG42806.1 - 4.5e-32 111.3 44.5 1.2e-27 96.8 19.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 OAG42806.1 - 3.2e-07 29.3 13.9 0.00013 20.6 1.4 3.2 3 0 0 3 3 3 2 MFS/sugar transport protein MFS_1_like PF12832.7 OAG42806.1 - 0.008 15.1 6.2 0.11 11.3 1.8 2.3 1 1 0 2 2 2 2 MFS_1 like family Mito_carr PF00153.27 OAG42808.1 - 4.9e-18 64.8 1.2 2e-10 40.5 0.0 3.2 3 1 0 3 3 3 2 Mitochondrial carrier protein POR_N PF01855.19 OAG42808.1 - 4.1 7.1 4.7 21 4.8 2.9 2.1 2 0 0 2 2 2 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg SPT16 PF08644.11 OAG42809.1 - 1e-55 188.0 0.1 1e-55 188.0 0.1 2.7 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.6 OAG42809.1 - 2.6e-50 170.3 0.2 2.6e-50 170.3 0.2 2.7 3 0 0 3 3 3 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.24 OAG42809.1 - 1.2e-27 97.0 0.0 2.4e-27 96.0 0.0 1.6 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 OAG42809.1 - 1.6e-14 54.1 0.2 1.1e-13 51.3 0.0 2.5 3 0 0 3 3 3 1 Histone chaperone Rttp106-like DUF3504 PF12012.8 OAG42809.1 - 4 7.3 9.4 7.8 6.4 0.1 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF3504) NAAA-beta PF15508.6 OAG42812.1 - 4.8e-13 49.2 0.0 9.3e-13 48.3 0.0 1.5 1 0 0 1 1 1 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Tyrosinase PF00264.20 OAG42813.1 - 1.4e-39 136.7 0.0 1.8e-39 136.3 0.0 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase SUI1 PF01253.22 OAG42814.1 - 3.3e-20 72.4 0.2 9.6e-20 70.9 0.1 1.9 2 0 0 2 2 2 1 Translation initiation factor SUI1 Pre-PUA PF17832.1 OAG42814.1 - 2.5e-10 40.9 0.4 1.9e-08 34.9 0.4 2.5 1 1 0 1 1 1 1 Pre-PUA-like domain Kin17_mid PF10357.9 OAG42814.1 - 0.037 13.9 0.2 0.079 12.9 0.2 1.5 1 0 0 1 1 1 0 Domain of Kin17 curved DNA-binding protein DUF1264 PF06884.11 OAG42815.1 - 4.1e-52 176.2 0.1 2e-49 167.5 0.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF1264) DUF2767 PF10965.8 OAG42815.1 - 0.027 14.5 0.0 0.047 13.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2767) adh_short PF00106.25 OAG42816.1 - 2.2e-47 161.1 0.0 2.7e-47 160.8 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG42816.1 - 8.5e-43 146.6 0.0 1.1e-42 146.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG42816.1 - 1.6e-07 31.4 0.0 2.8e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG42816.1 - 0.00042 19.9 0.1 0.00079 18.9 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 OAG42816.1 - 0.018 14.9 0.3 0.025 14.5 0.3 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 OAG42816.1 - 0.044 14.0 0.1 0.069 13.4 0.1 1.2 1 0 0 1 1 1 0 TrkA-N domain Velvet PF11754.8 OAG42818.1 - 7e-48 163.7 4.1 1.8e-31 110.0 0.0 3.1 1 1 2 3 3 3 2 Velvet factor BOP1NT PF08145.12 OAG42818.1 - 0.14 12.0 0.3 0.23 11.3 0.3 1.2 1 0 0 1 1 1 0 BOP1NT (NUC169) domain Ank_2 PF12796.7 OAG42819.1 - 1.1e-36 125.3 0.1 1.9e-12 47.6 0.0 4.2 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OAG42819.1 - 7.4e-29 96.6 2.7 5.3e-06 26.4 0.0 7.1 7 0 0 7 7 7 5 Ankyrin repeat Ank PF00023.30 OAG42819.1 - 3.6e-28 96.7 7.2 6.5e-08 32.7 0.1 6.8 7 0 0 7 7 7 5 Ankyrin repeat Ank_4 PF13637.6 OAG42819.1 - 4e-27 94.2 8.3 6.9e-08 32.9 0.0 5.5 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 OAG42819.1 - 5.6e-21 74.3 8.6 2.3e-08 34.1 0.1 5.5 1 1 4 5 5 5 5 Ankyrin repeats (many copies) DUF676 PF05057.14 OAG42819.1 - 0.00021 20.9 0.0 0.00034 20.2 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 OAG42819.1 - 0.00021 22.0 1.2 0.0015 19.2 0.2 2.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG42819.1 - 0.0075 15.6 0.0 0.015 14.6 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 LIDHydrolase PF10230.9 OAG42819.1 - 0.013 15.1 0.0 0.028 14.0 0.0 1.5 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase PGAP1 PF07819.13 OAG42819.1 - 0.031 14.0 0.0 0.058 13.1 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_3 PF07859.13 OAG42819.1 - 0.064 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold VPS28 PF03997.12 OAG42819.1 - 0.15 11.7 0.1 0.29 10.8 0.1 1.3 1 0 0 1 1 1 0 VPS28 protein Shisa PF13908.6 OAG42820.1 - 0.025 14.8 0.1 3.6 7.8 0.0 2.1 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator TMEM154 PF15102.6 OAG42820.1 - 0.11 12.4 1.2 0.72 9.8 0.0 2.0 2 0 0 2 2 2 0 TMEM154 protein family Cullin_binding PF03556.15 OAG42821.1 - 3.2e-31 108.3 1.3 4.4e-31 107.8 1.3 1.2 1 0 0 1 1 1 1 Cullin binding LBP_M PF17385.2 OAG42823.1 - 0.013 15.0 0.0 0.019 14.5 0.0 1.2 1 0 0 1 1 1 0 Lacto-N-biose phosphorylase central domain PGP_phosphatase PF09419.10 OAG42825.1 - 1.2e-51 174.6 0.0 1.5e-51 174.4 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.6 OAG42825.1 - 1.5e-07 31.4 0.0 2.7e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 OAG42825.1 - 0.024 14.9 0.0 1.9 8.7 0.0 2.1 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase LSM PF01423.22 OAG42826.1 - 8.3e-16 57.4 0.1 1.1e-15 57.1 0.1 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 OAG42826.1 - 0.073 13.2 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain Tail_tube PF10618.9 OAG42826.1 - 0.16 11.8 0.0 0.3 11.0 0.0 1.5 1 1 0 1 1 1 0 Phage tail tube protein Adaptin_binding PF10199.9 OAG42827.1 - 5e-10 40.0 3.2 5e-10 40.0 3.2 1.9 2 0 0 2 2 2 1 Alpha and gamma adaptin binding protein p34 BUD22 PF09073.10 OAG42827.1 - 0.2 10.9 7.2 0.26 10.6 7.2 1.3 1 0 0 1 1 1 0 BUD22 DUF4604 PF15377.6 OAG42828.1 - 1.8e-25 90.4 15.8 2.2e-25 90.1 15.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) DNApol_Exo PF18136.1 OAG42829.1 - 2.2e-104 348.6 0.0 3.8e-104 347.8 0.0 1.4 1 0 0 1 1 1 1 DNA mitochondrial polymerase exonuclease domain DNA_pol_A PF00476.20 OAG42829.1 - 8.8e-58 196.1 0.0 1.4e-57 195.5 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family A DNA_pol_A_exo1 PF01612.20 OAG42829.1 - 0.096 12.4 0.0 0.58 9.8 0.0 2.2 1 1 0 1 1 1 0 3'-5' exonuclease DUF1454 PF07305.12 OAG42829.1 - 0.14 11.6 0.0 0.33 10.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1454) PI3_PI4_kinase PF00454.27 OAG42830.1 - 8.7e-50 169.9 0.0 2e-49 168.6 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.8 OAG42830.1 - 1.4e-39 135.6 2.6 1.9e-39 135.2 0.1 2.5 2 0 0 2 2 2 1 Telomere-length maintenance and DNA damage repair FATC PF02260.20 OAG42830.1 - 2.2e-12 46.5 0.0 9.2e-12 44.6 0.0 2.0 2 0 0 2 2 2 1 FATC domain Nup192 PF11894.8 OAG42831.1 - 0 1059.8 0.1 0 1059.6 0.1 1.0 1 0 0 1 1 1 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 Cas_Cas02710 PF09670.10 OAG42831.1 - 0.081 11.7 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cas02710) Fe_dep_repr_C PF02742.15 OAG42832.1 - 0.15 12.1 0.2 0.45 10.6 0.2 1.7 1 0 0 1 1 1 0 Iron dependent repressor, metal binding and dimerisation domain FAD_binding_3 PF01494.19 OAG42833.1 - 7.7e-72 242.4 0.0 9.7e-72 242.1 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 OAG42833.1 - 6e-36 124.0 0.0 9.7e-36 123.3 0.0 1.3 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox_2 PF07992.14 OAG42833.1 - 2.7e-05 23.5 0.1 0.014 14.7 0.0 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAG42833.1 - 0.00037 20.2 0.3 0.032 13.8 0.1 2.2 1 1 1 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAG42833.1 - 0.01 16.1 0.0 0.032 14.5 0.0 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 OAG42833.1 - 0.023 13.4 0.0 0.059 12.1 0.0 1.7 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.27 OAG42833.1 - 0.024 15.2 0.1 0.14 12.7 0.0 2.3 2 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 OAG42833.1 - 0.044 13.4 0.1 0.13 11.9 0.0 1.8 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Lycopene_cycl PF05834.12 OAG42833.1 - 0.048 12.7 0.0 0.099 11.7 0.0 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein Cofilin_ADF PF00241.20 OAG42834.1 - 2.3e-17 62.9 0.0 2.9e-17 62.6 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein MoCF_biosynth PF00994.24 OAG42835.1 - 7.1e-33 113.3 0.0 2.9e-32 111.3 0.0 1.8 2 0 0 2 2 2 1 Probable molybdopterin binding domain FAD_syn PF06574.12 OAG42835.1 - 0.19 11.6 0.0 16 5.3 0.0 2.2 2 0 0 2 2 2 0 FAD synthetase Ras PF00071.22 OAG42836.1 - 2.6e-60 202.7 0.1 3e-60 202.5 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAG42836.1 - 1.9e-20 73.3 0.0 2.9e-20 72.7 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAG42836.1 - 8.9e-08 31.8 0.0 9.9e-08 31.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OAG42836.1 - 5.7e-06 26.0 0.1 3.3e-05 23.5 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OAG42836.1 - 0.00011 22.1 0.6 0.45 10.4 0.0 2.4 1 1 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OAG42836.1 - 0.0023 18.0 0.0 0.0035 17.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 OAG42836.1 - 0.004 17.1 0.0 0.0074 16.3 0.0 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain FeoB_N PF02421.18 OAG42836.1 - 0.008 15.7 0.0 0.013 15.1 0.0 1.3 1 1 0 1 1 1 1 Ferrous iron transport protein B DUF2075 PF09848.9 OAG42836.1 - 0.088 12.0 0.3 10 5.2 0.0 2.0 1 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) IstB_IS21 PF01695.17 OAG42836.1 - 0.12 12.1 0.5 1.6 8.5 0.1 2.1 1 1 1 2 2 2 0 IstB-like ATP binding protein Ser_hydrolase PF06821.13 OAG42836.1 - 0.19 11.5 0.0 0.27 11.1 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase zf-C2HE PF16278.5 OAG42837.1 - 1.5e-19 70.2 0.4 3.4e-19 69.1 0.4 1.6 1 0 0 1 1 1 1 C2HE / C2H2 / C2HC zinc-binding finger DcpS_C PF11969.8 OAG42837.1 - 1.3e-15 57.9 6.0 7.5e-15 55.4 6.0 2.0 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 OAG42837.1 - 3.7e-15 56.4 0.2 8.7e-15 55.3 0.2 1.6 1 1 0 1 1 1 1 HIT domain adh_short_C2 PF13561.6 OAG42839.1 - 2.1e-49 168.2 0.1 3.9e-49 167.3 0.1 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG42839.1 - 5.8e-49 166.2 0.3 8.9e-49 165.6 0.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG42839.1 - 3.9e-11 43.2 0.1 9.4e-11 41.9 0.1 1.6 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 OAG42839.1 - 0.00063 19.2 0.0 0.0013 18.2 0.0 1.4 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Acetyltransf_1 PF00583.25 OAG42840.1 - 5.5e-08 33.1 0.0 9.7e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OAG42840.1 - 2e-06 27.7 0.0 3.1e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OAG42840.1 - 1.3e-05 25.5 0.0 2.1e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Trypan_PARP PF05887.11 OAG42840.1 - 7.4e-05 22.7 3.5 7.4e-05 22.7 3.5 1.8 3 0 0 3 3 3 1 Procyclic acidic repetitive protein (PARP) Acetyltransf_13 PF13880.6 OAG42840.1 - 0.0015 18.5 0.0 0.0028 17.6 0.0 1.4 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase FR47 PF08445.10 OAG42840.1 - 0.0039 17.1 0.0 0.0073 16.3 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 OAG42840.1 - 0.067 13.3 0.1 0.16 12.1 0.1 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PanZ PF12568.8 OAG42840.1 - 0.13 12.0 0.1 0.23 11.2 0.1 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ Ribosom_S12_S23 PF00164.25 OAG42841.1 - 1.2e-17 63.6 0.3 1.6e-17 63.1 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Mcm10 PF09332.11 OAG42841.1 - 0.055 12.9 0.3 0.059 12.8 0.3 1.1 1 0 0 1 1 1 0 Mcm10 replication factor Glyco_transf_15 PF01793.16 OAG42842.1 - 4.5e-134 446.8 3.4 5.4e-134 446.5 3.4 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase PAT1 PF09770.9 OAG42843.1 - 0 1135.5 8.6 0 1129.6 8.6 2.0 1 1 0 1 1 1 1 Topoisomerase II-associated protein PAT1 MAM33 PF02330.16 OAG42844.1 - 0.0014 18.6 3.6 0.0022 18.0 3.6 1.2 1 0 0 1 1 1 1 Mitochondrial glycoprotein FMN_bind_2 PF04299.12 OAG42844.1 - 0.11 12.2 0.0 0.28 10.9 0.0 1.7 1 0 0 1 1 1 0 Putative FMN-binding domain Roughex PF06020.11 OAG42844.1 - 0.14 11.2 4.5 0.22 10.6 4.5 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Pox_Ag35 PF03286.14 OAG42844.1 - 1.9 8.2 7.7 3.6 7.3 7.7 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Nop14 PF04147.12 OAG42844.1 - 2 6.5 7.9 2.5 6.2 7.9 1.1 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.12 OAG42844.1 - 5.1 6.3 7.6 7.4 5.8 7.6 1.2 1 0 0 1 1 1 0 NOA36 protein DUF4637 PF15470.6 OAG42844.1 - 7.7 6.2 9.2 15 5.2 9.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) HCMVantigenic_N PF12154.8 OAG42844.1 - 8.5 6.6 9.4 3.3 7.9 5.6 2.3 2 0 0 2 2 2 0 Glycoprotein B N-terminal antigenic domain of HCMV Las1 PF04031.13 OAG42845.1 - 1.4e-37 129.2 2.5 5.5e-19 68.8 0.1 2.1 2 0 0 2 2 2 2 Las1-like DUF4031 PF13223.6 OAG42845.1 - 0.084 13.1 0.1 0.26 11.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4031) UCH PF00443.29 OAG42846.1 - 1.2e-35 123.2 0.0 2.2e-35 122.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OAG42846.1 - 4.8e-06 26.4 1.3 1.7e-05 24.6 1.3 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase PhdYeFM_antitox PF02604.19 OAG42846.1 - 0.15 11.9 0.1 0.44 10.4 0.0 1.8 2 0 0 2 2 2 0 Antitoxin Phd_YefM, type II toxin-antitoxin system NAD_kinase PF01513.21 OAG42847.1 - 1.8e-73 247.3 0.0 3.1e-73 246.5 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 OAG42847.1 - 0.027 14.1 0.0 0.091 12.4 0.0 1.8 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain TRAPP PF04051.16 OAG42848.1 - 3.9e-38 130.4 0.0 5.5e-38 130.0 0.0 1.2 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component DUF685 PF05085.12 OAG42848.1 - 0.76 9.0 2.5 1.3 8.2 1.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF685) MFAP1 PF06991.11 OAG42849.1 - 4.1e-63 213.1 22.6 4.1e-63 213.1 22.6 3.8 2 1 0 3 3 3 1 Microfibril-associated/Pre-mRNA processing Lipocalin_5 PF13924.6 OAG42850.1 - 1.6e-26 92.8 0.0 1.8e-26 92.6 0.0 1.1 1 0 0 1 1 1 1 Lipocalin-like domain CRAL_TRIO PF00650.20 OAG42851.1 - 2.9e-37 127.8 0.0 4.1e-37 127.3 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 OAG42851.1 - 5.2e-15 55.4 0.1 1e-14 54.4 0.1 1.5 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 OAG42851.1 - 0.062 13.5 0.0 0.095 12.8 0.0 1.3 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain CBS PF00571.28 OAG42852.1 - 1.2e-20 73.7 5.8 1.3e-08 35.1 0.0 4.3 4 0 0 4 4 4 3 CBS domain PrpR_N PF06506.11 OAG42852.1 - 0.066 12.8 0.0 0.18 11.4 0.0 1.7 1 1 0 1 1 1 0 Propionate catabolism activator Pol_alpha_B_N PF08418.10 OAG42853.1 - 7.5e-75 252.1 0.0 3e-74 250.1 0.0 1.8 2 0 0 2 2 2 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.16 OAG42853.1 - 9.4e-33 113.3 0.1 1.4e-32 112.8 0.1 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Apc13p PF05839.11 OAG42854.1 - 7.7e-15 54.9 0.0 2.1e-10 40.6 0.0 3.3 2 1 0 2 2 2 2 Apc13p protein Epimerase PF01370.21 OAG42856.1 - 2.5e-26 92.6 0.1 1.3e-25 90.3 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAG42856.1 - 3.7e-18 66.0 0.0 1e-17 64.6 0.0 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 OAG42856.1 - 2e-15 56.5 0.1 2e-14 53.3 0.1 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 OAG42856.1 - 3.5e-10 40.1 0.0 8e-10 38.9 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 OAG42856.1 - 5.5e-09 35.6 0.0 5.9e-06 25.6 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 OAG42856.1 - 2.4e-08 33.4 0.0 3.6e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 OAG42856.1 - 1.4e-06 27.7 0.0 0.00015 21.0 0.0 2.3 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.10 OAG42856.1 - 0.002 18.1 0.0 0.0052 16.7 0.0 1.7 1 1 0 1 1 1 1 KR domain adh_short PF00106.25 OAG42856.1 - 0.055 12.9 0.0 0.12 11.8 0.0 1.6 1 1 0 1 1 1 0 short chain dehydrogenase RestrictionSfiI PF11487.8 OAG42856.1 - 0.17 11.7 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 Type II restriction enzyme SfiI NmrA PF05368.13 OAG42856.1 - 0.2 11.2 0.1 0.82 9.2 0.0 1.8 2 0 0 2 2 2 0 NmrA-like family IF-2B PF01008.17 OAG42857.1 - 8.4e-69 231.9 0.1 1.1e-68 231.4 0.1 1.2 1 0 0 1 1 1 1 Initiation factor 2 subunit family Fungal_trans PF04082.18 OAG42859.1 - 1.3e-23 83.4 0.0 2.2e-23 82.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG42859.1 - 5.7e-06 26.4 11.3 1.1e-05 25.4 11.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MCM_OB PF17207.3 OAG42859.1 - 1.4 8.7 3.9 4 7.3 2.7 2.1 2 0 0 2 2 2 0 MCM OB domain PhrC_PhrF PF11131.8 OAG42860.1 - 0.18 11.4 3.0 7.4 6.3 0.3 3.4 3 0 0 3 3 3 0 Rap-phr extracellular signalling DUF4653 PF15546.6 OAG42860.1 - 1.5 8.4 3.7 2 8.0 3.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4653) Peptidase_S41 PF03572.18 OAG42862.1 - 6.2e-14 51.9 0.0 1.3e-13 50.9 0.0 1.5 1 1 0 1 1 1 1 Peptidase family S41 HET PF06985.11 OAG42863.1 - 1.1e-12 48.6 7.4 6e-10 39.7 0.5 2.6 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) HAD PF12710.7 OAG42864.1 - 1.5e-06 28.7 0.2 0.0014 19.1 0.0 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase DUF4266 PF14086.6 OAG42864.1 - 0.028 15.3 1.4 0.061 14.3 1.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4266) Kinesin PF00225.23 OAG42865.1 - 5.2e-113 377.3 0.0 5.2e-113 377.3 0.0 1.5 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 OAG42865.1 - 1.1e-25 90.4 1.4 7.5e-25 87.6 0.0 2.4 2 0 0 2 2 2 1 Microtubule binding DUF3138 PF11336.8 OAG42865.1 - 0.0074 15.0 2.0 0.014 14.1 2.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3138) DUF87 PF01935.17 OAG42865.1 - 0.082 13.0 8.8 0.7 9.9 0.0 3.0 3 0 0 3 3 3 0 Helicase HerA, central domain FAM76 PF16046.5 OAG42865.1 - 0.52 9.6 7.7 0.18 11.1 4.4 1.9 2 0 0 2 2 2 0 FAM76 protein DUF3037 PF11236.8 OAG42865.1 - 2.7 8.5 6.4 1.7 9.1 3.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3037) LNP1 PF15419.6 OAG42865.1 - 3.1 8.0 7.1 0.82 9.9 2.3 2.2 2 0 0 2 2 2 0 Leukemia NUP98 fusion partner 1 DUF4598 PF15370.6 OAG42866.1 - 2.3e-19 69.9 0.3 2.3e-19 69.9 0.3 3.2 2 1 1 3 3 2 1 Domain of unknown function (DUF4598) DNA_pol_phi PF04931.13 OAG42866.1 - 0.036 12.2 17.2 0.054 11.6 17.2 1.3 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 OAG42866.1 - 0.25 9.5 16.4 0.31 9.2 16.4 1.2 1 0 0 1 1 1 0 Nop14-like family TFIIA PF03153.13 OAG42866.1 - 1.1 9.2 19.5 1.8 8.5 19.5 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CCSAP PF15748.5 OAG42866.1 - 2.3 8.3 7.1 3.3 7.8 7.1 1.3 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated CDC45 PF02724.14 OAG42866.1 - 2.4 6.4 8.8 2.7 6.2 8.8 1.3 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 OAG42866.1 - 2.6 6.7 3.2 2.8 6.6 3.2 1.1 1 0 0 1 1 1 0 Presenilin NPR3 PF03666.13 OAG42866.1 - 2.9 6.6 4.9 3.8 6.2 4.9 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 MFMR_assoc PF16596.5 OAG42866.1 - 3.2 8.2 13.0 0.38 11.2 8.3 1.9 2 0 0 2 2 2 0 Disordered region downstream of MFMR NOA36 PF06524.12 OAG42866.1 - 7.6 5.8 14.6 14 4.9 14.6 1.5 1 0 0 1 1 1 0 NOA36 protein RRN3 PF05327.11 OAG42866.1 - 10 4.6 8.7 9.9 4.6 8.7 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 IF4E PF01652.18 OAG42867.1 - 6.8e-30 104.0 0.0 9e-30 103.6 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E COMPASS-Shg1 PF05205.12 OAG42868.1 - 1.7e-26 92.8 0.1 1.7e-26 92.8 0.1 2.4 3 0 0 3 3 3 1 COMPASS (Complex proteins associated with Set1p) component shg1 Response_reg PF00072.24 OAG42869.1 - 1.9e-24 86.0 0.0 4.3e-24 84.8 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 OAG42869.1 - 3.9e-23 82.1 0.0 9.5e-23 80.8 0.0 1.7 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 OAG42869.1 - 2.3e-15 56.4 0.0 8.2e-15 54.6 0.1 2.0 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 OAG42869.1 - 0.008 16.5 0.5 0.06 13.7 0.0 2.5 2 0 0 2 2 2 1 HAMP domain GFA PF04828.14 OAG42870.1 - 3.6e-13 49.7 1.3 2.2e-05 24.7 0.1 2.3 2 0 0 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme FerA PF08165.11 OAG42871.1 - 0.13 12.2 0.2 26 4.8 0.0 2.7 2 0 0 2 2 2 0 FerA (NUC095) domain SesA PF17107.5 OAG42871.1 - 0.16 12.2 0.5 4.5 7.5 0.1 3.2 2 2 1 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases zf-C3HC4 PF00097.25 OAG42872.1 - 0.35 10.8 8.7 0.91 9.5 8.7 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAG42872.1 - 1.9 8.5 9.8 3.4 7.7 9.8 1.4 1 0 0 1 1 1 0 zinc-RING finger domain Amidase PF01425.21 OAG42873.1 - 2.9e-50 171.6 0.2 1.2e-45 156.3 0.2 2.4 2 1 0 2 2 2 2 Amidase PAD_porph PF04371.15 OAG42874.1 - 2.1e-99 332.8 0.0 2.3e-99 332.7 0.0 1.0 1 0 0 1 1 1 1 Porphyromonas-type peptidyl-arginine deiminase Amidinotransf PF02274.17 OAG42874.1 - 0.076 12.1 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Amidinotransferase GTP_EFTU PF00009.27 OAG42875.1 - 6.2e-58 195.5 0.1 9e-58 195.0 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 OAG42875.1 - 8.8e-23 80.7 0.0 2.4e-22 79.3 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 OAG42875.1 - 1.5e-16 60.5 2.9 3.9e-16 59.2 2.9 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 OAG42875.1 - 2.6e-05 24.3 0.0 5e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase cobW PF02492.19 OAG42875.1 - 0.013 15.1 0.2 0.26 10.8 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 OAG42875.1 - 0.069 12.9 0.2 5.2 6.8 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 OAG42875.1 - 0.11 12.4 0.1 0.43 10.5 0.0 1.9 1 1 1 2 2 2 0 RsgA GTPase Pro_isomerase PF00160.21 OAG42876.1 - 2e-46 158.2 0.0 3.9e-46 157.2 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD U-box PF04564.15 OAG42876.1 - 1e-06 28.8 0.1 6.5e-06 26.2 0.0 2.2 1 1 1 2 2 2 1 U-box domain zf-NOSIP PF15906.5 OAG42876.1 - 4.5e-05 23.5 0.0 9.3e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein Rtf2 PF04641.12 OAG42876.1 - 0.13 11.6 11.0 0.27 10.6 7.4 2.7 2 1 0 2 2 2 0 Rtf2 RING-finger Amidoligase_2 PF12224.8 OAG42877.1 - 1.7e-08 34.4 0.2 0.0092 15.7 0.0 3.3 2 1 0 2 2 2 2 Putative amidoligase enzyme YjeF_N PF03853.15 OAG42879.1 - 1.7e-33 115.9 0.0 2.4e-33 115.4 0.0 1.3 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.10 OAG42879.1 - 3.5e-09 37.5 0.7 9.1e-09 36.1 0.7 1.7 1 0 0 1 1 1 1 FDF domain PIF1 PF05970.14 OAG42880.1 - 1.2e-63 215.5 2.0 8.2e-48 163.4 0.1 2.1 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 OAG42880.1 - 3.1e-23 82.5 0.0 5.4e-23 81.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OAG42880.1 - 2.5e-11 44.1 0.0 6.1e-11 42.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 OAG42880.1 - 1.5e-06 28.5 0.0 5.9e-06 26.6 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_7 PF12775.7 OAG42880.1 - 7e-05 22.4 0.0 0.00016 21.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region UvrD_C_2 PF13538.6 OAG42880.1 - 0.00017 21.3 0.0 0.00042 20.1 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain PhoH PF02562.16 OAG42880.1 - 0.00055 19.4 0.2 0.011 15.2 0.0 2.7 3 0 0 3 3 2 1 PhoH-like protein AAA PF00004.29 OAG42880.1 - 0.00065 20.1 0.1 0.0035 17.8 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OAG42880.1 - 0.0013 19.2 0.0 0.0039 17.6 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain Herpes_Helicase PF02689.14 OAG42880.1 - 0.0016 16.5 0.2 0.0045 15.0 0.0 1.7 2 0 0 2 2 2 1 Helicase ABC_tran PF00005.27 OAG42880.1 - 0.0031 18.1 0.0 0.019 15.5 0.0 2.4 1 1 0 1 1 1 1 ABC transporter NB-ARC PF00931.22 OAG42880.1 - 0.0084 15.3 0.1 0.015 14.5 0.1 1.4 1 0 0 1 1 1 1 NB-ARC domain NACHT PF05729.12 OAG42880.1 - 0.0097 15.8 0.0 0.027 14.4 0.0 1.8 1 0 0 1 1 1 1 NACHT domain RNA_helicase PF00910.22 OAG42880.1 - 0.011 16.1 0.0 0.046 14.1 0.0 2.2 1 1 0 1 1 1 0 RNA helicase AAA_14 PF13173.6 OAG42880.1 - 0.02 14.9 0.1 0.15 12.1 0.0 2.4 1 1 1 2 2 2 0 AAA domain UvrD-helicase PF00580.21 OAG42880.1 - 0.021 14.3 0.0 0.043 13.3 0.0 1.5 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain T2SSE PF00437.20 OAG42880.1 - 0.022 13.8 0.0 0.042 12.9 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF2075 PF09848.9 OAG42880.1 - 0.03 13.6 0.1 0.075 12.3 0.1 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Sigma54_activat PF00158.26 OAG42880.1 - 0.036 13.8 0.1 0.13 12.0 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain RsgA_GTPase PF03193.16 OAG42880.1 - 0.047 13.6 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 OAG42880.1 - 0.049 13.4 0.1 0.12 12.1 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATPase_2 PF01637.18 OAG42880.1 - 0.053 13.4 0.0 0.53 10.1 0.0 2.2 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea TsaE PF02367.17 OAG42880.1 - 0.077 13.0 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SH3_13 PF18335.1 OAG42880.1 - 0.082 12.7 0.1 0.22 11.4 0.1 1.7 1 0 0 1 1 1 0 ATP-dependent RecD-like DNA helicase SH3 domain ResIII PF04851.15 OAG42880.1 - 0.1 12.6 0.1 0.31 11.0 0.1 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_11 PF13086.6 OAG42880.1 - 0.38 10.5 2.2 0.75 9.5 0.0 2.5 3 1 0 3 3 2 0 AAA domain RRM_1 PF00076.22 OAG42881.1 - 1.3e-59 198.0 0.0 3e-21 75.0 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OAG42881.1 - 3.3e-08 33.3 0.0 0.0058 16.5 0.0 3.5 3 1 0 3 3 3 2 Occluded RNA-recognition motif RRM_5 PF13893.6 OAG42881.1 - 4e-08 32.9 0.0 0.00047 19.8 0.0 3.1 2 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 OAG42881.1 - 2.2e-06 27.5 0.1 0.2 11.7 0.0 3.4 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif RRM_8 PF11835.8 OAG42881.1 - 0.00021 21.4 0.0 0.22 11.7 0.0 2.3 2 0 0 2 2 2 2 RRM-like domain RRM_7 PF16367.5 OAG42881.1 - 0.00033 20.7 0.1 0.99 9.6 0.0 3.3 3 0 0 3 3 3 2 RNA recognition motif Cas_Cas2CT1978 PF09707.10 OAG42881.1 - 0.011 15.7 0.0 7.5 6.7 0.0 2.4 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cas2CT1978) OB_RNB PF08206.11 OAG42881.1 - 0.21 11.3 2.1 17 5.2 0.0 3.2 3 0 0 3 3 3 0 Ribonuclease B OB domain Med2 PF11214.8 OAG42882.1 - 7.6e-07 29.2 0.4 1.6e-06 28.2 0.4 1.4 1 0 0 1 1 1 1 Mediator complex subunit 2 SOG2 PF10428.9 OAG42882.1 - 4.1 6.5 16.1 5.3 6.1 16.1 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein ArAE_2_N PF10337.9 OAG42883.1 - 8.9e-41 140.4 6.9 1e-39 136.9 3.6 2.4 2 0 0 2 2 2 2 Putative ER transporter, 6TM, N-terminal FUSC_2 PF13515.6 OAG42883.1 - 9e-16 58.1 14.2 9e-16 58.1 14.2 3.8 2 1 1 4 4 4 1 Fusaric acid resistance protein-like ArAE_2 PF10334.9 OAG42883.1 - 1.5e-09 38.0 0.1 3.5e-09 36.8 0.1 1.6 1 0 0 1 1 1 1 Aromatic acid exporter family member 2 DUF2798 PF11391.8 OAG42883.1 - 0.021 14.9 1.5 0.021 14.9 1.5 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF2798) PBP PF01161.20 OAG42884.1 - 1.1e-07 32.2 0.0 1.9e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Peptidase_S26 PF10502.9 OAG42885.1 - 1.3e-07 31.5 0.0 1.3e-06 28.2 0.0 2.2 1 1 0 1 1 1 1 Signal peptidase, peptidase S26 Peptidase_S24 PF00717.23 OAG42885.1 - 0.0004 20.3 0.1 0.0012 18.8 0.1 1.8 2 0 0 2 2 2 1 Peptidase S24-like p450 PF00067.22 OAG42886.1 - 1.8e-67 228.1 0.0 2.4e-67 227.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AAT PF03417.16 OAG42887.1 - 2.6e-30 105.8 0.0 3.1e-30 105.6 0.0 1.0 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Polysacc_deac_1 PF01522.21 OAG42888.1 - 6.9e-18 64.7 0.0 1.1e-17 64.1 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 OAG42888.1 - 6.7e-12 45.5 0.1 1.1e-11 44.8 0.1 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) Glyco_hydro_57 PF03065.15 OAG42888.1 - 1.2e-05 24.7 0.0 2.3e-05 23.7 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 57 DUF2194 PF09960.9 OAG42888.1 - 0.087 11.2 0.1 0.12 10.7 0.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2194) MFS_1 PF07690.16 OAG42889.1 - 3.8e-32 111.6 22.1 3.8e-32 111.6 22.1 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily N36 PF11438.8 OAG42889.1 - 0.18 11.6 0.0 0.51 10.2 0.0 1.7 1 0 0 1 1 1 0 36-mer N-terminal peptide of the N protein (N36) adh_short PF00106.25 OAG42890.1 - 1.3e-41 142.2 1.0 1.7e-41 141.8 1.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG42890.1 - 1.3e-28 100.2 1.1 2.1e-28 99.4 1.1 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG42890.1 - 1.3e-06 28.5 0.4 2.1e-06 27.8 0.4 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OAG42890.1 - 1.3e-05 24.5 0.2 1.8e-05 24.1 0.2 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 OAG42890.1 - 2.6e-05 23.8 0.2 4.7e-05 23.0 0.2 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OAG42890.1 - 0.00019 20.5 1.0 0.00036 19.6 1.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 OAG42890.1 - 0.0016 17.9 0.2 0.0027 17.2 0.2 1.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase TrkA_N PF02254.18 OAG42890.1 - 0.0057 16.9 0.3 0.012 15.9 0.3 1.6 1 0 0 1 1 1 1 TrkA-N domain Fungal_trans PF04082.18 OAG42891.1 - 0.00032 19.8 0.1 0.00048 19.2 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.18 OAG42892.1 - 1.6e-17 63.4 0.0 2.7e-17 62.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aa_trans PF01490.18 OAG42893.1 - 4.5e-28 98.1 22.3 1.2e-27 96.7 22.4 1.6 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Glyco_hydro_127 PF07944.12 OAG42894.1 - 4.8e-19 68.3 0.0 1e-17 63.9 0.0 2.0 2 0 0 2 2 2 2 Beta-L-arabinofuranosidase, GH127 PLAC8 PF04749.17 OAG42895.1 - 4.8e-17 62.8 9.0 6.6e-17 62.3 9.0 1.2 1 0 0 1 1 1 1 PLAC8 family TFIIA PF03153.13 OAG42896.1 - 0.14 12.1 19.4 0.17 11.8 19.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit BUD22 PF09073.10 OAG42896.1 - 0.2 10.9 22.8 0.24 10.7 22.8 1.2 1 0 0 1 1 1 0 BUD22 Mpp10 PF04006.12 OAG42896.1 - 0.27 9.7 29.0 0.33 9.4 29.0 1.2 1 0 0 1 1 1 0 Mpp10 protein RNA_pol_Rpc4 PF05132.14 OAG42896.1 - 0.27 11.7 4.3 0.54 10.7 4.3 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 PPP4R2 PF09184.11 OAG42896.1 - 0.8 9.2 26.1 1.1 8.8 26.1 1.3 1 0 0 1 1 1 0 PPP4R2 DUF913 PF06025.12 OAG42896.1 - 3.3 6.6 5.4 4.2 6.2 5.4 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SAPS PF04499.15 OAG42896.1 - 4.8 5.8 10.1 5.6 5.6 10.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Nop14 PF04147.12 OAG42896.1 - 5.5 5.1 38.8 7.5 4.6 38.8 1.1 1 0 0 1 1 1 0 Nop14-like family Presenilin PF01080.17 OAG42896.1 - 6.9 5.3 6.2 8.1 5.1 6.2 1.1 1 0 0 1 1 1 0 Presenilin Pkinase PF00069.25 OAG42897.1 - 6e-38 130.7 0.0 1.7e-19 70.2 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAG42897.1 - 2.3e-14 53.3 0.0 1.3e-06 27.9 0.0 3.1 3 0 0 3 3 3 2 Protein tyrosine kinase Kdo PF06293.14 OAG42897.1 - 0.028 13.8 0.0 0.048 13.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OAG42897.1 - 0.061 13.2 0.1 0.2 11.6 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family p450 PF00067.22 OAG42898.1 - 3.7e-42 144.7 0.0 5.1e-42 144.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 adh_short_C2 PF13561.6 OAG42899.1 - 3.9e-63 213.1 5.0 4.7e-63 212.9 5.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG42899.1 - 9.9e-47 158.9 3.1 1.3e-46 158.6 3.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG42899.1 - 8.6e-11 42.1 1.7 1.3e-10 41.5 1.7 1.2 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 OAG42899.1 - 0.0018 17.3 0.0 0.0028 16.7 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 OAG42899.1 - 0.0026 17.3 0.7 0.0067 15.9 0.6 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 OAG42900.1 - 4.7e-23 81.7 0.0 1.2e-13 50.9 0.0 2.3 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAG42900.1 - 6e-20 71.8 0.0 6.9e-11 42.1 0.0 2.2 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Cyclase PF04199.13 OAG42901.1 - 4.7e-13 49.6 0.0 6.1e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase p450 PF00067.22 OAG42902.1 - 1.8e-69 234.7 0.0 2.8e-69 234.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_3 PF01494.19 OAG42903.1 - 1.7e-87 294.0 0.0 2.3e-87 293.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 OAG42903.1 - 2.1e-05 23.9 0.0 0.00011 21.6 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG42903.1 - 0.00026 21.2 0.1 0.00081 19.6 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 OAG42903.1 - 0.00048 19.5 0.0 0.012 14.9 0.0 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 OAG42903.1 - 0.00058 19.2 0.0 0.021 14.1 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAG42903.1 - 0.0036 16.1 0.0 0.56 8.9 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox PF00070.27 OAG42903.1 - 0.0075 16.8 0.0 0.063 13.8 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAA_hydrolase PF01557.18 OAG42904.1 - 3.2e-53 180.6 0.0 4e-53 180.3 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family AMP-binding PF00501.28 OAG42905.1 - 1.6e-40 139.0 0.0 2.3e-40 138.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG42905.1 - 0.0003 21.7 0.1 0.00081 20.3 0.1 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain TRI12 PF06609.13 OAG42906.1 - 1.8e-81 274.4 25.3 2.3e-81 274.0 25.3 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG42906.1 - 3.3e-22 78.9 56.7 4.7e-20 71.8 53.3 3.1 2 1 0 2 2 2 2 Major Facilitator Superfamily CoA_binding_3 PF13727.6 OAG42906.1 - 0.022 14.8 0.9 0.022 14.8 0.9 2.4 2 0 0 2 2 2 0 CoA-binding domain FAD_binding_2 PF00890.24 OAG42907.1 - 7.7e-94 315.1 0.1 8.7e-94 314.9 0.1 1.0 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAG42907.1 - 3.3e-12 46.7 3.6 7.6e-07 29.0 0.2 3.1 3 0 0 3 3 3 2 FAD dependent oxidoreductase FAD_oxidored PF12831.7 OAG42907.1 - 1.3e-11 44.5 0.7 1.2e-09 38.0 0.3 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 OAG42907.1 - 5.5e-09 35.2 0.1 8.3e-09 34.6 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 OAG42907.1 - 2.6e-08 33.4 0.1 6e-08 32.2 0.1 1.5 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 OAG42907.1 - 1.2e-07 31.9 0.6 5.8e-07 29.6 0.4 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAG42907.1 - 3.5e-06 26.5 0.1 6.6e-06 25.6 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG42907.1 - 0.0065 15.8 0.1 0.011 15.1 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OAG42907.1 - 0.015 14.4 0.2 0.024 13.7 0.2 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.22 OAG42907.1 - 0.025 13.6 5.6 0.015 14.4 3.1 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A Trp_halogenase PF04820.14 OAG42907.1 - 0.085 11.7 0.0 0.21 10.4 0.1 1.5 2 0 0 2 2 2 0 Tryptophan halogenase FAD_binding_3 PF01494.19 OAG42907.1 - 0.12 11.5 0.3 0.22 10.8 0.3 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.6 OAG42907.1 - 0.15 12.1 0.0 0.33 10.9 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding GDI PF00996.18 OAG42907.1 - 0.22 10.0 0.0 0.39 9.2 0.0 1.3 1 0 0 1 1 1 0 GDP dissociation inhibitor Pyr_redox PF00070.27 OAG42907.1 - 0.29 11.7 1.6 1 9.9 0.6 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 OAG42907.1 - 0.68 9.2 2.6 0.65 9.2 1.1 1.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.14 OAG42908.1 - 9.1e-14 51.4 0.0 2.1e-09 37.0 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG42908.1 - 3.2e-10 39.8 0.1 1.4e-08 34.3 0.0 2.5 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAG42908.1 - 2.3e-09 37.3 0.8 9.6e-06 25.4 0.5 3.2 3 0 0 3 3 3 2 FAD dependent oxidoreductase FMO-like PF00743.19 OAG42908.1 - 5.4e-08 31.7 0.1 1.6e-06 26.8 0.0 2.7 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OAG42908.1 - 9.9e-07 28.9 2.3 1.2e-06 28.7 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 OAG42908.1 - 1.9e-05 24.0 0.1 2.8e-05 23.4 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Shikimate_DH PF01488.20 OAG42908.1 - 7.1e-05 22.9 0.2 0.03 14.4 0.2 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.17 OAG42908.1 - 0.00043 19.6 0.0 0.00086 18.6 0.0 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 OAG42908.1 - 0.00065 19.7 0.2 0.089 12.8 0.2 3.3 4 0 0 4 4 4 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 OAG42908.1 - 0.00078 18.6 0.0 0.003 16.7 0.0 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_3 PF01494.19 OAG42908.1 - 0.00095 18.5 1.0 0.0022 17.3 0.7 1.8 2 0 0 2 2 2 1 FAD binding domain TrkA_N PF02254.18 OAG42908.1 - 0.034 14.4 0.5 0.95 9.7 0.1 3.0 3 0 0 3 3 3 0 TrkA-N domain Pyr_redox PF00070.27 OAG42908.1 - 0.035 14.7 0.4 3.5 8.3 0.9 2.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 OAG42908.1 - 0.073 12.4 0.0 0.19 11.0 0.0 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain K_oxygenase PF13434.6 OAG42908.1 - 0.13 11.4 0.1 17 4.4 0.1 3.3 3 1 1 4 4 4 0 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 OAG42908.1 - 0.23 10.1 0.1 0.71 8.5 0.3 1.7 2 0 0 2 2 2 0 HI0933-like protein Fungal_trans PF04082.18 OAG42909.1 - 4.4e-19 68.5 0.3 6.5e-19 68.0 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.18 OAG42910.1 - 5.3e-15 55.2 0.8 1.1e-14 54.1 0.8 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Glyoxalase PF00903.25 OAG42911.1 - 2.1e-10 40.9 0.0 3.2e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 OAG42911.1 - 0.01 16.6 0.0 0.029 15.2 0.0 1.7 1 1 1 2 2 2 1 Glyoxalase-like domain DUF4859 PF16151.5 OAG42911.1 - 0.17 11.7 0.0 0.42 10.5 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4859) adh_short PF00106.25 OAG42912.1 - 8.1e-31 107.0 0.0 1.2e-30 106.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG42912.1 - 7.1e-24 84.6 0.0 9.4e-24 84.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG42912.1 - 2.8e-07 30.6 0.0 4.5e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG42912.1 - 0.0017 17.8 0.0 0.0026 17.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Catalase PF00199.19 OAG42913.1 - 1.2e-173 577.6 0.3 8.5e-173 574.8 0.1 1.9 2 0 0 2 2 2 1 Catalase Catalase-rel PF06628.12 OAG42913.1 - 8.1e-08 32.4 0.1 2.6e-07 30.7 0.1 1.9 1 1 0 1 1 1 1 Catalase-related immune-responsive Aldo_ket_red PF00248.21 OAG42914.1 - 1.3e-39 136.1 0.0 4e-39 134.6 0.0 1.7 1 1 0 1 1 1 1 Aldo/keto reductase family Macoilin PF09726.9 OAG42915.1 - 0.45 9.0 11.8 0.6 8.6 11.8 1.1 1 0 0 1 1 1 0 Macoilin family DUF2956 PF11169.8 OAG42915.1 - 7.8 6.8 22.6 0.86 9.8 1.3 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF2956) HA2 PF04408.23 OAG42916.1 - 2.1e-24 85.9 1.9 5.4e-24 84.6 0.1 2.7 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 OAG42916.1 - 3e-20 72.4 0.0 6e-20 71.4 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 OAG42916.1 - 3.5e-13 49.9 0.0 8.8e-13 48.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.23 OAG42916.1 - 1.9e-08 34.5 0.2 4.6e-08 33.3 0.2 1.7 1 0 0 1 1 1 1 S1 RNA binding domain DEAD PF00270.29 OAG42916.1 - 2.4e-05 24.2 0.1 5.5e-05 23.0 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 OAG42916.1 - 0.00017 21.8 0.0 0.00045 20.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 OAG42916.1 - 0.00041 20.1 0.7 0.0017 18.1 0.0 2.3 3 0 0 3 3 3 1 AAA domain T2SSE PF00437.20 OAG42916.1 - 0.0006 19.0 0.0 0.0017 17.5 0.0 1.7 1 0 0 1 1 1 1 Type II/IV secretion system protein DUF2075 PF09848.9 OAG42916.1 - 0.012 14.9 0.0 0.027 13.7 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 OAG42916.1 - 0.012 15.9 0.1 0.029 14.7 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 OAG42916.1 - 0.027 14.6 0.0 0.17 12.0 0.0 2.5 1 0 0 1 1 1 0 AAA domain Thioredoxin_5 PF13743.6 OAG42916.1 - 0.027 14.1 2.3 1.6 8.4 0.0 3.1 3 0 0 3 3 3 0 Thioredoxin AAA_16 PF13191.6 OAG42916.1 - 0.057 13.8 0.0 0.24 11.8 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain Microtub_bd PF16796.5 OAG42916.1 - 0.065 13.2 0.8 0.85 9.5 0.0 2.6 3 0 0 3 3 3 0 Microtubule binding ABC_tran PF00005.27 OAG42916.1 - 6.5 7.3 7.7 1.4 9.4 0.1 3.4 3 1 1 4 4 4 0 ABC transporter SUV3_C PF12513.8 OAG42917.1 - 1.3e-16 60.3 1.7 2.5e-16 59.3 1.7 1.5 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.31 OAG42917.1 - 2.1e-10 40.9 0.1 4.6e-10 39.8 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Suv3_C_1 PF18147.1 OAG42917.1 - 0.00074 19.3 0.4 0.0014 18.5 0.4 1.5 1 0 0 1 1 1 1 Suv3 C-terminal domain 1 ADSL_C PF10397.9 OAG42917.1 - 0.087 13.4 0.2 0.26 11.9 0.2 1.8 1 0 0 1 1 1 0 Adenylosuccinate lyase C-terminus Sec1 PF00995.23 OAG42918.1 - 1.6e-120 404.1 0.1 1.9e-120 403.8 0.1 1.0 1 0 0 1 1 1 1 Sec1 family G-patch PF01585.23 OAG42919.1 - 4.8e-08 32.8 0.1 8.7e-08 31.9 0.1 1.4 1 0 0 1 1 1 1 G-patch domain adh_short PF00106.25 OAG42920.1 - 2.3e-12 46.8 0.0 7.3e-11 41.9 0.0 2.7 2 1 0 2 2 2 1 short chain dehydrogenase Epimerase PF01370.21 OAG42920.1 - 4.6e-06 26.3 0.0 7.8e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 OAG42920.1 - 0.00029 20.8 0.0 0.00053 20.0 0.0 1.5 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 OAG42920.1 - 0.0012 18.5 0.0 0.0081 15.7 0.0 2.1 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase GDP_Man_Dehyd PF16363.5 OAG42920.1 - 0.018 14.5 0.1 2.7 7.3 0.0 2.3 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase GFA PF04828.14 OAG42921.1 - 8.6e-11 42.0 0.1 1.1e-10 41.6 0.1 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Nudix_N_2 PF14803.6 OAG42921.1 - 0.01 15.7 0.0 0.018 14.9 0.0 1.4 1 0 0 1 1 1 0 Nudix N-terminal p450 PF00067.22 OAG42922.1 - 2.9e-68 230.7 0.0 3.6e-68 230.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SUIM_assoc PF16619.5 OAG42922.1 - 0.047 13.8 0.3 17 5.6 0.0 2.5 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 YiiD_C PF09500.10 OAG42922.1 - 0.091 12.6 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Putative thioesterase (yiiD_Cterm) HAD PF12710.7 OAG42923.1 - 2.6e-17 63.8 0.0 4.1e-17 63.2 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 OAG42923.1 - 0.00049 19.6 0.1 0.15 11.5 0.1 2.2 2 0 0 2 2 2 2 Putative Phosphatase UMPH-1 PF05822.12 OAG42923.1 - 0.0037 16.8 0.0 0.008 15.7 0.0 1.6 1 1 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) She9_MDM33 PF05546.11 OAG42924.1 - 4.1e-86 287.8 7.6 7.3e-86 287.0 7.6 1.4 1 0 0 1 1 1 1 She9 / Mdm33 family Alpha_L_fucos PF01120.17 OAG42924.1 - 0.051 13.0 0.2 0.075 12.5 0.2 1.3 1 0 0 1 1 1 0 Alpha-L-fucosidase Cpn60_TCP1 PF00118.24 OAG42924.1 - 0.089 11.4 0.1 0.14 10.7 0.1 1.2 1 0 0 1 1 1 0 TCP-1/cpn60 chaperonin family Uso1_p115_C PF04871.13 OAG42924.1 - 0.12 12.8 0.0 0.12 12.8 0.0 3.6 4 0 0 4 4 4 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF3818 PF12825.7 OAG42924.1 - 0.13 11.2 2.2 0.22 10.5 2.2 1.3 1 0 0 1 1 1 0 Domain of unknown function in PX-proteins (DUF3818) FliJ PF02050.16 OAG42924.1 - 0.17 12.1 0.2 0.17 12.1 0.2 3.4 4 0 0 4 4 4 0 Flagellar FliJ protein DUF445 PF04286.12 OAG42924.1 - 4.5 7.0 7.7 19 4.9 0.2 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF445) PsbH PF00737.20 OAG42924.1 - 7.5 6.4 7.5 0.43 10.4 1.4 1.9 2 0 0 2 2 2 0 Photosystem II 10 kDa phosphoprotein Rieske PF00355.26 OAG42925.1 - 1.7e-11 43.9 0.0 2.9e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.14 OAG42925.1 - 3.3e-10 40.3 0.1 7.5e-10 39.2 0.1 1.6 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region CorA PF01544.18 OAG42927.1 - 0.00044 19.7 5.3 0.00077 18.9 5.3 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Pkinase PF00069.25 OAG42928.1 - 3.9e-09 36.2 0.0 1.1e-08 34.8 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain DUF1490 PF07371.12 OAG42928.1 - 0.19 11.8 0.0 0.84 9.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1490) CBFD_NFYB_HMF PF00808.23 OAG42929.1 - 1.1e-10 41.6 0.7 1.1e-10 41.6 0.7 2.0 3 0 0 3 3 3 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 OAG42929.1 - 0.0098 16.3 0.3 0.0098 16.3 0.3 1.8 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 TAFII28 PF04719.14 OAG42929.1 - 0.022 14.8 0.6 0.046 13.8 0.1 1.7 2 0 0 2 2 2 0 hTAFII28-like protein conserved region PFK PF00365.20 OAG42929.1 - 0.044 13.1 0.1 0.053 12.9 0.1 1.1 1 0 0 1 1 1 0 Phosphofructokinase Voltage_CLC PF00654.20 OAG42930.1 - 4.7e-89 299.1 25.3 4.7e-89 299.1 25.3 1.8 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 OAG42930.1 - 3.5e-14 53.0 0.7 1.8e-06 28.3 0.1 2.6 2 0 0 2 2 2 2 CBS domain DUF4064 PF13273.6 OAG42930.1 - 0.018 15.3 1.2 0.018 15.3 1.2 4.0 3 2 0 3 3 3 0 Protein of unknown function (DUF4064) SKA2 PF16740.5 OAG42931.1 - 0.018 14.8 0.1 0.035 13.9 0.1 1.6 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 Sec1 PF00995.23 OAG42931.1 - 0.051 12.8 0.0 0.054 12.7 0.0 1.1 1 0 0 1 1 1 0 Sec1 family HBM PF16591.5 OAG42931.1 - 0.065 12.7 1.6 0.1 12.0 1.1 1.5 1 1 0 1 1 1 0 Helical bimodular sensor domain Bap31_Bap29_C PF18035.1 OAG42931.1 - 1 9.4 6.5 0.3 11.1 3.2 1.9 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain DNA_pol_delta_4 PF04081.13 OAG42932.1 - 1e-30 106.8 19.1 2.2e-28 99.2 0.0 3.1 2 1 0 2 2 2 2 DNA polymerase delta, subunit 4 Citrate_bind PF16114.5 OAG42933.1 - 4.8e-89 296.5 0.0 6.9e-89 296.0 0.0 1.2 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding ATP-grasp_2 PF08442.10 OAG42933.1 - 2.1e-07 30.7 0.0 3.2e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain Reovirus_M2 PF05993.12 OAG42933.1 - 0.063 11.4 0.1 0.092 10.8 0.1 1.1 1 0 0 1 1 1 0 Reovirus major virion structural protein Mu-1/Mu-1C (M2) Citrate_synt PF00285.21 OAG42934.1 - 4.8e-21 75.2 0.0 3.7e-17 62.4 0.0 3.0 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain CoA_binding PF02629.19 OAG42934.1 - 7.2e-19 68.3 0.0 1.8e-18 67.0 0.0 1.7 1 0 0 1 1 1 1 CoA binding domain Ligase_CoA PF00549.19 OAG42934.1 - 1.6e-15 57.3 0.1 2.5e-15 56.6 0.1 1.3 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 OAG42934.1 - 0.0036 17.1 0.0 0.016 15.0 0.0 1.9 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain Amidase PF01425.21 OAG42935.1 - 1.1e-98 331.1 0.0 1.8e-98 330.5 0.0 1.3 1 1 0 1 1 1 1 Amidase UPF0180 PF03698.13 OAG42935.1 - 0.16 12.2 0.0 0.35 11.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0180) Rick_17kDa_Anti PF05433.15 OAG42936.1 - 0.00045 20.0 9.5 0.00094 19.0 9.5 1.6 1 0 0 1 1 1 1 Glycine zipper 2TM domain DUF456 PF04306.13 OAG42936.1 - 0.099 12.9 0.2 0.14 12.4 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF456) Transgly_assoc PF04226.13 OAG42936.1 - 5.5 7.3 12.0 10 6.5 12.0 1.4 1 0 0 1 1 1 0 Transglycosylase associated protein FMO-like PF00743.19 OAG42937.1 - 2e-15 56.2 0.0 1.9e-14 53.0 0.0 2.0 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OAG42937.1 - 8.7e-15 54.8 0.0 8.3e-13 48.3 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAG42937.1 - 1.4e-10 41.0 0.0 5.8e-08 32.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG42937.1 - 4.5e-06 26.8 0.0 2.1e-05 24.7 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 OAG42937.1 - 1.5e-05 24.3 0.0 0.00022 20.5 0.0 2.0 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 OAG42937.1 - 0.0004 20.4 2.6 0.13 12.2 0.4 4.0 3 2 0 3 3 3 1 FAD-NAD(P)-binding 2-Hacid_dh_C PF02826.19 OAG42937.1 - 0.012 15.0 0.0 0.022 14.1 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 OAG42937.1 - 0.013 14.7 0.0 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Ish1 PF10281.9 OAG42937.1 - 0.19 12.0 0.8 0.49 10.7 0.8 1.7 1 0 0 1 1 1 0 Putative stress-responsive nuclear envelope protein adh_short_C2 PF13561.6 OAG42938.1 - 1.8e-49 168.5 4.5 2e-48 165.0 4.5 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG42938.1 - 1.5e-38 132.2 1.7 8.2e-38 129.8 1.7 1.9 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG42938.1 - 3.1e-07 30.5 0.3 4.7e-07 29.9 0.3 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG42938.1 - 7.4e-07 28.9 0.1 7.8e-07 28.8 0.1 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 OAG42938.1 - 6.4e-06 26.2 0.2 9e-06 25.7 0.2 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 OAG42938.1 - 5e-05 22.9 0.0 8.1e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Sacchrp_dh_NADP PF03435.18 OAG42938.1 - 6.6e-05 23.2 0.1 0.00012 22.4 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain 3Beta_HSD PF01073.19 OAG42938.1 - 8.4e-05 21.7 0.2 0.00012 21.2 0.2 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 OAG42938.1 - 0.0027 16.9 0.1 0.004 16.3 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein F420_oxidored PF03807.17 OAG42938.1 - 0.034 14.7 0.1 0.066 13.8 0.1 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.18 OAG42938.1 - 0.036 14.3 0.1 0.061 13.6 0.1 1.3 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_10 PF13460.6 OAG42938.1 - 0.054 13.4 0.2 0.099 12.5 0.2 1.4 1 0 0 1 1 1 0 NAD(P)H-binding UDPG_MGDP_dh_N PF03721.14 OAG42938.1 - 0.072 12.7 0.1 0.1 12.2 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Sugar_tr PF00083.24 OAG42939.1 - 3.2e-96 323.0 27.6 3.8e-96 322.7 27.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG42939.1 - 4.2e-22 78.6 56.5 2e-20 73.0 31.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily CPP1-like PF11833.8 OAG42939.1 - 0.023 14.3 0.4 0.023 14.3 0.4 2.3 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Phage_holin_3_2 PF04550.12 OAG42939.1 - 4.3 8.0 11.7 8.5 7.0 0.1 2.8 2 0 0 2 2 2 0 Phage holin family 2 DUF1129 PF06570.11 OAG42939.1 - 7.6 6.0 15.6 4 6.9 4.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) zf-RING_UBOX PF13445.6 OAG42940.1 - 3.5e-05 23.7 3.2 7.9e-05 22.6 3.2 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 OAG42940.1 - 0.0001 22.6 3.0 0.0001 22.6 3.0 1.9 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 OAG42940.1 - 0.00018 21.3 4.0 0.00018 21.3 4.0 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OAG42940.1 - 0.0002 21.1 3.3 0.0002 21.1 3.3 1.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAG42940.1 - 0.00047 20.0 1.4 0.00047 20.0 1.4 1.6 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 OAG42940.1 - 0.00061 19.6 2.8 0.0013 18.5 2.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OAG42940.1 - 0.0044 17.2 2.9 0.01 16.0 2.9 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 OAG42940.1 - 0.02 14.6 5.9 0.03 14.1 4.4 2.0 2 0 0 2 2 2 0 RING-like zinc finger RRM_DME PF15628.6 OAG42940.1 - 0.023 14.8 0.2 0.05 13.8 0.0 1.6 2 0 0 2 2 2 0 RRM in Demeter zf-RING_6 PF14835.6 OAG42940.1 - 0.03 14.2 3.0 0.058 13.3 1.8 1.9 2 0 0 2 2 2 0 zf-RING of BARD1-type protein Prok-RING_4 PF14447.6 OAG42940.1 - 0.037 13.9 4.4 0.079 12.8 4.4 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 YvfG PF09628.10 OAG42940.1 - 0.078 13.3 0.0 10 6.6 0.0 2.8 3 0 0 3 3 3 0 YvfG protein NmrA PF05368.13 OAG42941.1 - 1.1e-20 74.1 0.0 1.5e-20 73.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG42941.1 - 6.2e-17 62.1 0.0 1.8e-16 60.6 0.0 1.7 1 1 1 2 2 2 1 NAD(P)H-binding Shikimate_DH PF01488.20 OAG42941.1 - 4.2e-05 23.6 0.0 8.4e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 OAG42941.1 - 4.3e-05 23.8 0.0 7.1e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 OAG42941.1 - 0.00015 22.2 0.0 0.00029 21.3 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Glu_dehyd_C PF16912.5 OAG42941.1 - 0.00033 20.2 0.0 0.00057 19.4 0.0 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus NAD_binding_4 PF07993.12 OAG42941.1 - 0.004 16.3 0.0 0.0055 15.9 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.19 OAG42941.1 - 0.009 15.0 0.0 0.014 14.4 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.20 OAG42941.1 - 0.01 15.9 0.2 0.03 14.5 0.0 1.8 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Epimerase PF01370.21 OAG42941.1 - 0.049 13.1 0.0 0.1 12.0 0.0 1.5 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.17 OAG42941.1 - 0.062 13.9 0.1 0.18 12.4 0.0 1.8 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA PF01408.22 OAG42941.1 - 0.11 13.3 0.0 0.22 12.3 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold S1-P1_nuclease PF02265.16 OAG42942.1 - 1.4e-60 205.3 0.1 1.8e-60 204.9 0.1 1.1 1 0 0 1 1 1 1 S1/P1 Nuclease Transglut_core PF01841.19 OAG42943.1 - 6.2e-12 46.0 0.0 1.2e-11 45.0 0.0 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF553 PF04473.12 OAG42943.1 - 0.033 13.7 0.0 1.4 8.5 0.0 2.8 1 1 0 1 1 1 0 Transglutaminase-like domain Gln_amidase PF15644.6 OAG42943.1 - 0.17 12.9 0.0 0.48 11.5 0.0 2.0 1 1 0 1 1 1 0 Papain fold toxin 1, glutamine deamidase MFS_1 PF07690.16 OAG42944.1 - 1.6e-18 66.8 10.9 3.1e-18 65.9 10.4 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.13 OAG42944.1 - 0.013 15.0 5.5 0.044 13.3 3.7 2.3 2 1 0 2 2 2 0 Nodulin-like SPT6_acidic PF14632.6 OAG42944.1 - 0.12 12.9 5.0 4.1 8.1 0.2 2.5 2 0 0 2 2 2 0 Acidic N-terminal SPT6 EMP70 PF02990.16 OAG42944.1 - 2.7 6.6 7.3 0.075 11.7 0.8 1.6 2 0 0 2 2 2 0 Endomembrane protein 70 RPN1_RPN2_N PF17781.1 OAG42945.1 - 3.3e-117 391.3 1.7 6.2e-117 390.4 1.7 1.5 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 OAG42945.1 - 1.7e-27 95.2 0.0 3.1e-27 94.4 0.0 1.5 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 OAG42945.1 - 1.2e-22 79.1 12.0 2.5e-06 27.6 0.1 8.5 9 1 0 9 9 9 4 Proteasome/cyclosome repeat HEAT_2 PF13646.6 OAG42945.1 - 1.3e-07 31.9 2.0 0.00099 19.5 0.0 4.7 6 2 1 7 7 7 2 HEAT repeats IFRD PF05004.13 OAG42945.1 - 0.002 17.3 0.1 0.012 14.7 0.0 2.3 1 1 0 1 1 1 1 Interferon-related developmental regulator (IFRD) TPR_12 PF13424.6 OAG42945.1 - 0.057 13.7 0.8 9 6.7 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Ribosomal_L23 PF00276.20 OAG42946.1 - 2.2e-09 37.5 0.0 4.4e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L23 Retrotrans_gag PF03732.17 OAG42946.1 - 0.039 14.2 0.8 0.098 12.9 0.8 1.6 1 0 0 1 1 1 0 Retrotransposon gag protein Lon_C PF05362.13 OAG42947.1 - 1.7e-73 246.5 0.8 1.2e-72 243.7 0.8 2.2 2 0 0 2 2 2 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 OAG42947.1 - 6.9e-29 101.2 0.0 1.6e-28 100.0 0.0 1.7 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 OAG42947.1 - 1.4e-23 83.7 0.0 1.7e-22 80.3 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 OAG42947.1 - 6e-08 32.8 0.0 1.5e-07 31.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.6 OAG42947.1 - 4.1e-07 29.9 0.0 9.6e-07 28.7 0.0 1.7 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_16 PF13191.6 OAG42947.1 - 9.6e-06 26.1 0.1 5.5e-05 23.6 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.17 OAG42947.1 - 3.1e-05 23.8 0.0 7.6e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.13 OAG42947.1 - 4.4e-05 22.9 0.0 9.9e-05 21.7 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 OAG42947.1 - 0.0002 21.6 0.2 0.0095 16.2 0.0 3.2 2 1 1 3 3 3 1 AAA domain AAA_3 PF07726.11 OAG42947.1 - 0.00025 20.9 0.0 0.0008 19.3 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 OAG42947.1 - 0.00072 19.3 0.1 0.0025 17.6 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 OAG42947.1 - 0.0013 18.9 0.0 0.0042 17.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) Birna_VP4 PF01768.16 OAG42947.1 - 0.0045 16.8 0.1 0.011 15.6 0.1 1.6 1 0 0 1 1 1 1 Birnavirus VP4 protein AAA_33 PF13671.6 OAG42947.1 - 0.018 15.2 0.0 0.049 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 OAG42947.1 - 0.02 14.3 0.0 0.045 13.2 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_7 PF12775.7 OAG42947.1 - 0.027 14.0 0.0 0.053 13.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 OAG42947.1 - 0.029 14.3 0.0 0.14 12.0 0.0 2.2 3 0 0 3 3 1 0 NACHT domain AAA_25 PF13481.6 OAG42947.1 - 0.029 13.9 0.0 0.072 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_PrkA PF08298.11 OAG42947.1 - 0.052 12.4 0.1 0.55 9.1 0.1 2.1 2 0 0 2 2 2 0 PrkA AAA domain Mg_chelatase PF01078.21 OAG42947.1 - 0.053 12.9 0.1 0.12 11.8 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 OAG42947.1 - 0.059 13.9 0.3 0.22 12.1 0.0 2.1 2 0 0 2 2 1 0 AAA domain AAA_23 PF13476.6 OAG42947.1 - 0.072 13.6 0.0 0.072 13.6 0.0 2.6 1 1 1 2 2 1 0 AAA domain RNA_helicase PF00910.22 OAG42947.1 - 0.078 13.4 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Rad17 PF03215.15 OAG42947.1 - 0.085 12.8 0.0 0.22 11.4 0.0 1.7 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_24 PF13479.6 OAG42947.1 - 0.092 12.5 0.0 0.23 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 OAG42947.1 - 0.092 12.5 1.3 0.14 11.9 0.1 1.9 1 1 1 2 2 2 0 AAA domain TniB PF05621.11 OAG42947.1 - 0.11 11.9 0.0 0.29 10.5 0.0 1.7 1 0 0 1 1 1 0 Bacterial TniB protein ABC_tran PF00005.27 OAG42947.1 - 0.12 12.9 0.1 0.49 10.9 0.0 2.0 2 0 0 2 2 1 0 ABC transporter AAA_14 PF13173.6 OAG42947.1 - 0.13 12.3 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 OAG42947.1 - 0.18 11.8 0.0 0.39 10.7 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE APG6_N PF17675.1 OAG42947.1 - 4.6 7.8 5.8 17 5.9 5.8 2.0 1 1 0 1 1 1 0 Apg6 coiled-coil region Porphobil_deam PF01379.20 OAG42948.1 - 1.5e-68 230.3 0.0 2e-68 229.9 0.0 1.2 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 OAG42948.1 - 8.4e-16 58.1 0.1 1.5e-15 57.3 0.1 1.4 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain ORF_12_N PF18042.1 OAG42948.1 - 0.065 13.7 0.1 0.15 12.5 0.1 1.6 1 0 0 1 1 1 0 ORF 12 gene product N-terminal Na_Ca_ex_C PF16494.5 OAG42948.1 - 0.16 12.5 0.2 0.29 11.6 0.2 1.3 1 0 0 1 1 1 0 C-terminal extension of sodium/calcium exchanger domain TAP42 PF04177.12 OAG42949.1 - 1.8e-98 329.6 0.7 2e-98 329.5 0.7 1.0 1 0 0 1 1 1 1 TAP42-like family Cytochrom_B562 PF07361.11 OAG42949.1 - 0.0058 17.3 0.1 0.014 16.0 0.1 1.7 1 0 0 1 1 1 1 Cytochrome b562 HisKA PF00512.25 OAG42949.1 - 0.052 13.6 0.1 0.18 11.9 0.1 2.0 1 0 0 1 1 1 0 His Kinase A (phospho-acceptor) domain Cupin_8 PF13621.6 OAG42950.1 - 1.1e-30 107.3 0.0 1.7e-30 106.6 0.0 1.3 1 0 0 1 1 1 1 Cupin-like domain LCM PF04072.14 OAG42950.1 - 5.9e-19 68.7 0.0 1.5e-18 67.4 0.0 1.6 2 0 0 2 2 2 1 Leucine carboxyl methyltransferase Kelch_4 PF13418.6 OAG42950.1 - 3.6e-09 36.5 10.9 6.9e-05 22.8 0.0 5.2 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_3 PF13415.6 OAG42950.1 - 8.6e-05 22.7 1.5 0.0089 16.3 0.2 3.8 3 0 0 3 3 3 1 Galactose oxidase, central domain Cupin_4 PF08007.12 OAG42950.1 - 0.00031 20.3 0.0 0.0007 19.2 0.0 1.5 1 0 0 1 1 1 1 Cupin superfamily protein Kelch_5 PF13854.6 OAG42950.1 - 0.0091 16.0 0.7 0.57 10.2 0.0 3.3 4 0 0 4 4 4 1 Kelch motif Kelch_2 PF07646.15 OAG42950.1 - 0.016 15.2 0.7 11 6.1 0.0 3.3 3 0 0 3 3 3 0 Kelch motif Kelch_6 PF13964.6 OAG42950.1 - 0.019 15.3 0.4 16 6.0 0.0 3.3 3 0 0 3 3 3 0 Kelch motif DSPc PF00782.20 OAG42951.1 - 4.9e-27 94.3 0.0 2.9e-20 72.4 0.0 2.4 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 OAG42951.1 - 3.8e-05 23.4 0.0 0.00062 19.4 0.0 2.1 2 0 0 2 2 2 1 Protein-tyrosine phosphatase BLOC1_2 PF10046.9 OAG42953.1 - 0.0051 17.1 4.3 0.018 15.4 1.4 2.7 2 0 0 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 UNC45-central PF11701.8 OAG42954.1 - 3.2e-37 127.9 0.0 1.3e-36 125.8 0.0 2.2 2 0 0 2 2 2 1 Myosin-binding striated muscle assembly central PUL PF08324.11 OAG42954.1 - 0.012 14.9 0.5 4.9 6.3 0.1 3.0 2 1 0 2 2 2 0 PUL domain Arm PF00514.23 OAG42954.1 - 0.048 13.7 15.4 28 4.9 0.0 7.7 9 0 0 9 9 9 0 Armadillo/beta-catenin-like repeat Tfb4 PF03850.14 OAG42955.1 - 1.2e-90 303.8 0.1 1.5e-53 182.1 0.0 2.2 2 0 0 2 2 2 2 Transcription factor Tfb4 Sporozoite_P67 PF05642.11 OAG42955.1 - 0.53 8.3 6.0 0.78 7.7 6.0 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Asparaginase_2 PF01112.18 OAG42956.1 - 5.7e-48 163.5 4.9 2.3e-33 115.6 0.0 2.2 2 0 0 2 2 2 2 Asparaginase EccE PF11203.8 OAG42956.1 - 0.05 13.9 0.0 0.16 12.3 0.0 1.8 1 0 0 1 1 1 0 Putative type VII ESX secretion system translocon, EccE Actin PF00022.19 OAG42957.1 - 3.3e-88 296.0 0.0 3.3e-54 184.1 0.0 2.0 1 1 1 2 2 2 2 Actin MreB_Mbl PF06723.13 OAG42957.1 - 0.038 12.8 0.0 1.2 7.9 0.0 2.2 2 0 0 2 2 2 0 MreB/Mbl protein Ntox14 PF15522.6 OAG42958.1 - 0.026 14.0 0.0 0.048 13.1 0.0 1.4 1 0 0 1 1 1 0 Novel toxin 14 tRNA_U5-meth_tr PF05958.11 OAG42959.1 - 1.2e-14 54.1 0.0 4.4e-14 52.2 0.0 1.9 2 1 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase PrmA PF06325.13 OAG42959.1 - 8.9e-06 25.3 0.0 1.3e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_15 PF09445.10 OAG42959.1 - 0.00013 21.6 0.0 0.00021 20.9 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_25 PF13649.6 OAG42959.1 - 0.00016 22.3 0.0 0.0004 21.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG42959.1 - 0.0027 17.5 0.0 0.0049 16.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG42959.1 - 0.012 16.2 0.0 0.028 15.1 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 OAG42959.1 - 0.14 12.0 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain RCR PF12273.8 OAG42960.1 - 0.00021 21.9 0.1 0.00042 21.0 0.1 1.5 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red Herpes_gE PF02480.16 OAG42960.1 - 0.0083 14.9 0.1 0.011 14.5 0.1 1.1 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E TMEM154 PF15102.6 OAG42960.1 - 0.009 15.9 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 TMEM154 protein family Adeno_PV PF03910.13 OAG42960.1 - 0.045 12.5 4.4 0.061 12.0 4.4 1.1 1 0 0 1 1 1 0 Adenovirus minor core protein PV stn_TNFRSF12A PF12191.8 OAG42960.1 - 0.076 13.2 0.5 0.15 12.3 0.3 1.7 1 1 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain EphA2_TM PF14575.6 OAG42960.1 - 0.17 12.8 0.0 0.32 11.9 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain OB_NTP_bind PF07717.16 OAG42961.1 - 1e-21 77.1 0.0 3e-21 75.5 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 OAG42961.1 - 9.8e-19 67.6 0.1 2.8e-18 66.2 0.0 1.8 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 OAG42961.1 - 1.7e-11 44.4 0.0 6.1e-11 42.7 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 OAG42961.1 - 5.4e-07 29.5 0.2 1e-06 28.6 0.2 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 OAG42961.1 - 2.9e-06 27.6 0.1 8.9e-06 26.0 0.1 1.8 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 OAG42961.1 - 0.00012 21.8 0.1 0.00035 20.3 0.1 1.7 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain Flavi_DEAD PF07652.14 OAG42961.1 - 0.00043 20.3 0.1 0.00093 19.2 0.1 1.5 1 0 0 1 1 1 1 Flavivirus DEAD domain AAA_19 PF13245.6 OAG42961.1 - 0.0019 18.5 0.1 0.0041 17.5 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 OAG42961.1 - 0.004 16.9 0.0 0.0072 16.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 OAG42961.1 - 0.016 14.3 0.0 0.032 13.3 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_23 PF13476.6 OAG42961.1 - 0.019 15.5 0.0 0.038 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 OAG42961.1 - 0.031 13.8 0.0 0.082 12.4 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF2075 PF09848.9 OAG42961.1 - 0.14 11.3 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) TIM PF00121.18 OAG42962.1 - 9.8e-90 300.2 0.0 1.1e-89 300.0 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase PEX-1N PF09262.11 OAG42962.1 - 0.06 13.8 0.0 0.12 12.8 0.0 1.4 1 0 0 1 1 1 0 Peroxisome biogenesis factor 1, N-terminal CutC PF03932.14 OAG42962.1 - 0.077 12.5 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 CutC family Tom22 PF04281.13 OAG42963.1 - 3.3e-42 143.5 0.1 3.8e-42 143.3 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 Cg6151-P PF10233.9 OAG42963.1 - 0.16 12.3 0.0 0.22 11.9 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein CG6151-P DUF4211 PF13926.6 OAG42964.1 - 3.7e-38 130.8 0.1 2.3e-37 128.3 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4211) RGCC PF15151.6 OAG42964.1 - 0.0015 18.8 1.7 0.0051 17.0 1.7 1.9 1 0 0 1 1 1 1 Response gene to complement 32 protein family SLX9 PF15341.6 OAG42964.1 - 3.4 8.1 12.4 0.66 10.4 3.6 2.9 3 0 0 3 3 3 0 Ribosome biogenesis protein SLX9 DUF4449 PF14613.6 OAG42965.1 - 5.7e-64 215.1 5.3 5.7e-64 215.1 5.3 3.3 2 1 1 3 3 3 1 Protein of unknown function (DUF4449) PHA_gran_rgn PF09650.10 OAG42965.1 - 0.022 15.1 0.8 0.073 13.4 0.2 2.2 2 0 0 2 2 2 0 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) zf-C3HC4_3 PF13920.6 OAG42967.1 - 8.1e-09 35.2 11.8 1.3e-08 34.5 11.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Androgen_recep PF02166.16 OAG42968.1 - 2.1 7.1 9.7 3.1 6.5 9.7 1.2 1 0 0 1 1 1 0 Androgen receptor Fungal_trans PF04082.18 OAG42969.1 - 1.5e-09 37.3 1.9 1.5e-09 37.3 1.9 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2_4 PF13894.6 OAG42969.1 - 1.2e-06 28.8 9.2 0.0011 19.7 1.6 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 OAG42969.1 - 3.6e-06 27.1 14.7 0.00072 19.9 2.7 3.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 OAG42969.1 - 0.029 14.7 0.0 0.071 13.4 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 OAG42969.1 - 0.055 13.2 1.2 0.16 11.8 1.2 1.8 1 0 0 1 1 1 0 zinc-finger C2H2-type zf-Di19 PF05605.12 OAG42969.1 - 0.12 12.7 2.8 0.32 11.3 2.8 1.7 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.6 OAG42969.1 - 1.9 9.0 15.4 0.25 11.8 2.6 3.5 3 0 0 3 3 3 0 Zinc-finger double domain ADH_zinc_N PF00107.26 OAG42970.1 - 4.4e-24 84.9 0.6 7.3e-24 84.2 0.6 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAG42970.1 - 5.3e-17 63.1 0.1 1.3e-16 61.9 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG42970.1 - 8.5e-11 41.7 0.7 9.4e-10 38.4 0.7 2.2 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 OAG42970.1 - 0.023 14.0 0.0 0.062 12.6 0.0 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain DctP PF03480.13 OAG42970.1 - 0.04 13.3 0.0 6.3 6.0 0.0 2.3 2 0 0 2 2 2 0 Bacterial extracellular solute-binding protein, family 7 Asp PF00026.23 OAG42971.1 - 6.4e-70 236.1 8.4 7.7e-70 235.8 8.4 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OAG42971.1 - 1.2e-10 41.9 5.5 4.9e-05 23.6 0.1 3.1 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 OAG42971.1 - 0.00053 20.6 1.1 0.26 11.9 0.2 3.3 2 1 0 2 2 2 2 Aspartyl protease Amidohydro_3 PF07969.11 OAG42972.1 - 4.2e-84 283.7 5.0 4.8e-84 283.5 5.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 OAG42972.1 - 2.1e-13 50.3 0.0 3.6e-09 36.4 0.0 3.0 2 1 0 2 2 2 2 Amidohydrolase family RNA_pol_Rpb2_5 PF04567.17 OAG42972.1 - 0.077 13.6 0.0 0.23 12.1 0.0 1.8 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 5 Fungal_trans_2 PF11951.8 OAG42973.1 - 2.9e-20 72.4 0.3 4.1e-20 71.9 0.3 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG42973.1 - 3.3e-07 30.3 12.6 6.2e-07 29.4 12.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.24 OAG42974.1 - 5.9e-120 401.2 24.2 6.8e-120 401.0 24.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG42974.1 - 3.3e-24 85.5 52.7 1.3e-19 70.3 27.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily SecA_DEAD PF07517.14 OAG42974.1 - 0.12 11.7 0.5 0.19 11.0 0.5 1.2 1 0 0 1 1 1 0 SecA DEAD-like domain IF-2B PF01008.17 OAG42976.1 - 1e-21 77.4 0.5 1.1e-12 47.8 0.0 2.1 2 0 0 2 2 2 2 Initiation factor 2 subunit family NUDIX PF00293.28 OAG42976.1 - 1.1e-08 35.2 0.3 2.7e-08 33.9 0.1 1.8 2 0 0 2 2 2 1 NUDIX domain FAD_binding_3 PF01494.19 OAG42977.1 - 1.1e-25 90.6 0.0 1.7e-25 90.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 OAG42977.1 - 0.003 17.8 0.0 0.0086 16.3 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAG42977.1 - 0.0037 16.5 0.5 0.99 8.6 0.1 2.2 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 OAG42977.1 - 0.03 13.4 0.0 0.08 12.0 0.0 1.7 1 1 0 1 1 1 0 Squalene epoxidase Lycopene_cycl PF05834.12 OAG42977.1 - 0.058 12.4 0.1 0.66 9.0 0.1 2.2 1 1 0 1 1 1 0 Lycopene cyclase protein FAD_binding_2 PF00890.24 OAG42977.1 - 0.085 11.9 0.9 0.22 10.6 0.3 1.9 2 0 0 2 2 2 0 FAD binding domain IMUP PF15761.5 OAG42978.1 - 0.0047 17.6 0.3 0.0077 16.9 0.3 1.2 1 0 0 1 1 1 1 Immortalisation up-regulated protein AraC_binding PF02311.19 OAG42978.1 - 0.0084 16.0 0.0 0.017 15.0 0.0 1.5 1 0 0 1 1 1 1 AraC-like ligand binding domain TPP_enzyme_C PF02775.21 OAG42978.1 - 0.055 13.2 0.1 0.096 12.5 0.1 1.3 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Fungal_trans_2 PF11951.8 OAG42979.1 - 5.4e-05 22.2 0.4 7.8e-05 21.7 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain ADH_zinc_N PF00107.26 OAG42980.1 - 3e-22 79.0 0.9 5.5e-22 78.1 0.9 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG42980.1 - 8.9e-10 38.4 1.6 2.4e-08 33.8 0.0 2.8 1 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 OAG42980.1 - 3.4e-05 24.9 0.1 6.6e-05 24.0 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 OAG42980.1 - 0.011 15.7 0.5 0.017 15.0 0.1 1.6 2 0 0 2 2 2 0 N-terminal domain of oxidoreductase adh_short PF00106.25 OAG42980.1 - 0.028 13.9 1.1 0.12 11.8 0.4 2.0 2 0 0 2 2 2 0 short chain dehydrogenase adh_short_C2 PF13561.6 OAG42981.1 - 6.6e-48 163.3 0.0 7.7e-48 163.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG42981.1 - 3.7e-37 127.7 0.0 5.1e-37 127.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG42981.1 - 2.1e-14 53.9 0.4 3e-14 53.3 0.4 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG42981.1 - 6.3e-10 38.9 0.1 1.3e-09 37.9 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAG42981.1 - 1.5e-08 34.4 0.1 7.9e-08 32.1 0.1 1.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 OAG42981.1 - 0.00029 19.9 0.0 0.00037 19.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 OAG42981.1 - 0.02 14.8 0.1 0.045 13.6 0.0 1.7 2 0 0 2 2 2 0 NAD(P)H-binding DapB_N PF01113.20 OAG42981.1 - 0.02 15.0 0.0 0.036 14.2 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Polysacc_synt_2 PF02719.15 OAG42981.1 - 0.021 13.9 0.1 0.042 13.0 0.0 1.5 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 OAG42981.1 - 0.023 13.8 0.1 0.035 13.2 0.1 1.5 1 1 0 1 1 1 0 RmlD substrate binding domain NAD_binding_4 PF07993.12 OAG42981.1 - 0.024 13.8 0.0 0.12 11.6 0.0 1.9 2 0 0 2 2 2 0 Male sterility protein NmrA PF05368.13 OAG42981.1 - 0.035 13.7 0.0 0.058 12.9 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family Amdo_NSP PF12475.8 OAG42981.1 - 0.16 12.1 0.0 0.4 10.8 0.0 1.6 1 0 0 1 1 1 0 Amdovirus non-structural protein MFS_1 PF07690.16 OAG42983.1 - 4.5e-40 137.7 25.6 4.5e-40 137.7 25.6 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 OAG42983.1 - 1.7e-05 23.5 4.6 1.7e-05 23.5 4.6 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF3669 PF12417.8 OAG42984.1 - 1.2e-17 63.8 0.4 3.7e-17 62.3 0.1 1.9 2 0 0 2 2 2 1 Zinc finger protein Pyr_redox_3 PF13738.6 OAG42985.1 - 7.1e-11 41.9 0.0 0.00026 20.4 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAG42985.1 - 2.2e-10 40.3 0.0 7e-08 32.1 0.0 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 OAG42985.1 - 2.1e-09 36.4 0.1 2.6e-08 32.8 0.1 2.0 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 OAG42985.1 - 0.00088 18.5 1.7 0.0018 17.5 0.0 2.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 OAG42985.1 - 0.0035 17.9 1.1 1.4 9.6 0.1 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Peptidase_S9 PF00326.21 OAG42986.1 - 5.3e-10 39.1 0.0 1.4e-09 37.8 0.0 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 OAG42986.1 - 2.2e-09 37.5 0.0 1.3e-08 34.9 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAG42986.1 - 3.6e-06 26.4 0.0 5.5e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Say1_Mug180 PF10340.9 OAG42986.1 - 5.1e-05 22.3 0.0 7.3e-05 21.8 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_6 PF12697.7 OAG42986.1 - 0.01 16.4 1.0 0.015 15.9 1.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family APH PF01636.23 OAG42987.1 - 1.1e-15 58.3 0.1 1.7e-15 57.6 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 OAG42987.1 - 0.0021 17.7 0.0 0.0038 16.8 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase SNCAIP_SNCA_bd PF16700.5 OAG42987.1 - 0.15 11.8 0.0 3 7.6 0.0 2.3 2 0 0 2 2 2 0 Synphilin-1 alpha-Synuclein-binding domain KRAB PF01352.27 OAG42987.1 - 0.71 9.6 2.1 1.4 8.7 0.2 2.2 2 0 0 2 2 2 0 KRAB box Aa_trans PF01490.18 OAG42988.1 - 8.5e-20 70.8 40.0 4.8e-19 68.3 40.0 1.8 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein NADH_Oxid_Nqo15 PF11497.8 OAG42988.1 - 0.089 12.8 0.1 5.9 6.9 0.1 2.4 2 0 0 2 2 2 0 NADH-quinone oxidoreductase chain 15 MDM10 PF12519.8 OAG42989.1 - 8.1e-133 443.7 4.9 1.1e-130 436.7 4.9 2.0 1 1 0 1 1 1 1 Mitochondrial distribution and morphology protein 10 FAD_binding_3 PF01494.19 OAG42990.1 - 4.6e-17 62.3 0.4 1.2e-13 51.1 0.3 2.9 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 OAG42990.1 - 0.025 14.8 0.0 0.15 12.3 0.0 2.2 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain GDP_Man_Dehyd PF16363.5 OAG42991.1 - 2.3e-50 171.9 0.0 4.3e-50 171.0 0.0 1.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 OAG42991.1 - 1.5e-45 155.5 0.0 2e-45 155.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OAG42991.1 - 1.4e-17 63.6 0.0 2e-17 63.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 OAG42991.1 - 2.3e-13 49.9 0.0 1e-11 44.5 0.0 2.2 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 OAG42991.1 - 1.5e-12 47.2 0.0 2.1e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 OAG42991.1 - 1.7e-07 30.9 0.0 2.7e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.12 OAG42991.1 - 1.8e-06 27.3 0.0 0.00014 21.2 0.0 2.3 1 1 0 1 1 1 1 Male sterility protein KR PF08659.10 OAG42991.1 - 5.3e-05 23.2 0.0 0.0001 22.3 0.0 1.5 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 OAG42991.1 - 0.0023 17.5 0.0 0.0037 16.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NmrA PF05368.13 OAG42991.1 - 0.08 12.5 0.0 0.5 9.9 0.0 2.0 2 0 0 2 2 2 0 NmrA-like family UDPG_MGDP_dh_N PF03721.14 OAG42991.1 - 0.11 12.0 0.1 0.22 11.0 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NUC153 PF08159.12 OAG42992.1 - 1.2e-17 63.4 6.9 4.8e-15 55.1 0.4 3.8 3 0 0 3 3 3 3 NUC153 domain 2-Hacid_dh_C PF02826.19 OAG42993.1 - 8.3e-51 171.9 0.0 1.7e-50 170.8 0.0 1.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 OAG42993.1 - 8.1e-16 57.9 0.0 1.2e-15 57.4 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 OAG42993.1 - 0.0014 18.8 0.0 0.0045 17.2 0.0 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase DUF1640 PF07798.11 OAG42994.1 - 2.3e-32 112.4 6.9 2.3e-32 112.4 6.9 2.0 2 1 1 3 3 3 1 Protein of unknown function (DUF1640) LapA_dom PF06305.11 OAG42994.1 - 1.4 8.8 4.5 0.51 10.2 0.3 2.3 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain DUF4407 PF14362.6 OAG42994.1 - 1.4 8.2 16.9 0.017 14.5 8.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Cut12 PF11500.8 OAG42995.1 - 1.4e-08 34.8 0.6 3.5e-08 33.5 0.6 1.7 1 0 0 1 1 1 1 Spindle pole body formation-associated protein Myc-LZ PF02344.15 OAG42995.1 - 0.015 15.4 3.2 0.015 15.4 3.2 2.7 3 0 0 3 3 3 0 Myc leucine zipper domain Jnk-SapK_ap_N PF09744.9 OAG42995.1 - 0.02 15.1 1.8 0.048 13.9 1.8 1.6 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 UPF0242 PF06785.11 OAG42995.1 - 0.091 12.9 1.3 0.15 12.2 1.3 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus HAUS6_N PF14661.6 OAG42995.1 - 0.11 12.1 2.2 0.19 11.3 2.2 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Tho2 PF11262.8 OAG42995.1 - 0.15 11.3 3.0 0.25 10.5 3.0 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 IFT20 PF14931.6 OAG42995.1 - 0.52 10.5 4.6 0.98 9.6 4.6 1.4 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 D123 PF07065.14 OAG42996.1 - 4.1e-113 377.6 0.0 5.2e-113 377.2 0.0 1.1 1 0 0 1 1 1 1 D123 GATase PF00117.28 OAG42999.1 - 4.6e-47 160.3 0.0 6.3e-47 159.8 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.22 OAG42999.1 - 6.4e-45 152.1 0.0 1.2e-44 151.3 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain Peptidase_C26 PF07722.13 OAG42999.1 - 3.9e-05 23.5 0.1 0.0013 18.6 0.1 2.5 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.24 OAG42999.1 - 0.0081 16.0 0.0 0.014 15.2 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family DUF2967 PF11179.8 OAG42999.1 - 0.18 9.9 1.1 0.28 9.2 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) Bud13 PF09736.9 OAG43000.1 - 5.5 7.4 7.8 0.8 10.1 3.5 1.8 2 0 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex FAD_binding_3 PF01494.19 OAG43001.1 - 1.1e-79 268.2 0.0 1.7e-79 267.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain PTR2 PF00854.21 OAG43003.1 - 1.5e-71 241.4 0.4 2.1e-71 240.9 0.4 1.2 1 0 0 1 1 1 1 POT family MFS_1 PF07690.16 OAG43003.1 - 1.2e-08 34.2 16.1 1.2e-08 34.2 16.1 2.9 2 2 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG43003.1 - 9.3e-05 21.5 13.4 0.0035 16.3 0.4 3.2 3 0 0 3 3 3 2 Sugar (and other) transporter Vps51 PF08700.11 OAG43004.1 - 1.1e-09 38.2 0.1 7.6e-09 35.5 0.0 2.4 2 0 0 2 2 2 1 Vps51/Vps67 DUF3209 PF11483.8 OAG43004.1 - 0.033 14.6 0.4 0.097 13.1 0.4 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3209) GCP_N_terminal PF17681.1 OAG43004.1 - 0.057 13.0 0.1 0.15 11.6 0.1 1.8 1 0 0 1 1 1 0 Gamma tubulin complex component N-terminal LXG PF04740.12 OAG43004.1 - 0.16 11.7 0.9 0.73 9.5 0.2 2.3 2 0 0 2 2 2 0 LXG domain of WXG superfamily Transcrip_reg PF01709.20 OAG43005.1 - 1.2e-60 205.0 1.7 1.3e-60 204.8 1.7 1.0 1 0 0 1 1 1 1 Transcriptional regulator DUF3646 PF12362.8 OAG43005.1 - 0.011 16.0 0.4 0.021 15.1 0.4 1.4 1 0 0 1 1 1 0 DNA polymerase III gamma and tau subunits C terminal LAL_C2 PF18603.1 OAG43005.1 - 0.082 13.1 0.4 4.9 7.4 0.0 3.1 4 0 0 4 4 4 0 L-amino acid ligase C-terminal domain 2 Es2 PF09751.9 OAG43007.1 - 3.1e-107 360.0 7.3 3.8e-107 359.7 7.3 1.1 1 0 0 1 1 1 1 Nuclear protein Es2 TPR_2 PF07719.17 OAG43008.1 - 2.1e-20 71.1 32.1 0.015 15.4 0.3 13.4 13 0 0 13 13 13 6 Tetratricopeptide repeat TPR_19 PF14559.6 OAG43008.1 - 2.7e-14 53.4 32.4 0.0011 19.4 0.3 10.3 9 2 1 10 10 9 4 Tetratricopeptide repeat TPR_1 PF00515.28 OAG43008.1 - 9e-11 41.1 30.4 0.0034 17.1 0.4 11.8 13 0 0 13 13 13 3 Tetratricopeptide repeat TPR_14 PF13428.6 OAG43008.1 - 2.2e-08 34.3 46.7 0.37 11.7 0.8 13.5 11 5 4 15 15 14 4 Tetratricopeptide repeat TPR_12 PF13424.6 OAG43008.1 - 3.7e-08 33.5 31.8 0.17 12.2 0.9 10.8 12 0 0 12 12 12 3 Tetratricopeptide repeat TPR_8 PF13181.6 OAG43008.1 - 1.5e-07 31.1 25.9 0.72 10.2 0.1 11.0 14 0 0 14 14 13 3 Tetratricopeptide repeat TPR_16 PF13432.6 OAG43008.1 - 2.1e-05 25.1 45.1 0.015 15.9 0.8 8.2 8 1 1 9 9 8 4 Tetratricopeptide repeat TPR_11 PF13414.6 OAG43008.1 - 4.9e-05 22.9 17.1 4.9 6.9 0.5 8.0 7 0 0 7 7 7 2 TPR repeat ANAPC3 PF12895.7 OAG43008.1 - 0.00028 21.0 12.1 0.12 12.6 1.0 5.5 6 0 0 6 6 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 OAG43008.1 - 0.0011 19.2 29.0 1.5 9.4 0.2 10.9 13 0 0 13 13 13 2 Tetratricopeptide repeat TPR_7 PF13176.6 OAG43008.1 - 0.061 13.4 24.0 0.58 10.3 0.1 8.4 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_6 PF13174.6 OAG43008.1 - 0.071 13.8 26.4 6.2 7.7 0.1 11.1 12 0 0 12 12 11 0 Tetratricopeptide repeat TPR_3 PF07720.12 OAG43008.1 - 0.27 11.3 15.0 5.5 7.1 0.6 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat RSN1_7TM PF02714.15 OAG43009.1 - 4.9e-89 298.3 17.4 8.2e-89 297.6 17.4 1.4 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_ext PF12621.8 OAG43009.1 - 1.2e-26 92.7 0.1 4.5e-26 90.9 0.0 2.0 2 0 0 2 2 2 1 Extracellular tail, of 10TM putative phosphate transporter PHM7_cyt PF14703.6 OAG43009.1 - 4e-23 82.5 0.7 7.1e-23 81.7 0.7 1.4 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 OAG43009.1 - 0.00014 21.6 2.1 0.00023 21.0 0.1 2.4 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport RRM_1 PF00076.22 OAG43009.1 - 0.03 14.2 0.0 0.081 12.7 0.0 1.7 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Zn_clus PF00172.18 OAG43010.1 - 0.13 12.4 10.1 0.34 11.1 10.1 1.7 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain TauD PF02668.16 OAG43011.1 - 2.1e-20 73.6 0.0 3.1e-20 73.1 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 OAG43011.1 - 0.012 14.8 0.0 0.019 14.1 0.0 1.3 1 0 0 1 1 1 0 CsiD Acetyltransf_10 PF13673.7 OAG43012.1 - 9.7e-10 38.5 0.0 2e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OAG43012.1 - 5.3e-06 26.8 0.0 1.6e-05 25.3 0.0 1.8 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAG43012.1 - 0.00017 21.8 0.0 0.00034 20.8 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 OAG43012.1 - 0.0023 18.0 0.1 0.015 15.4 0.0 2.3 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain MFS_1 PF07690.16 OAG43013.1 - 0.00012 21.2 15.1 0.00022 20.3 15.1 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily DcuA_DcuB PF03605.14 OAG43013.1 - 0.0068 15.3 0.2 0.019 13.9 0.0 1.6 2 0 0 2 2 2 1 Anaerobic c4-dicarboxylate membrane transporter Dioxygenase_C PF00775.21 OAG43014.1 - 5.1e-37 127.1 0.0 6.6e-37 126.7 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 OAG43014.1 - 7.7e-24 83.3 0.0 1.3e-23 82.6 0.0 1.4 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 OAG43014.1 - 9.7e-05 22.6 0.1 0.00029 21.1 0.1 1.8 1 1 0 1 1 1 1 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 OAG43014.1 - 0.013 15.5 0.0 0.68 10.0 0.0 2.4 2 0 0 2 2 2 0 CarboxypepD_reg-like domain Big_1 PF02369.16 OAG43014.1 - 0.033 14.2 0.0 0.075 13.0 0.0 1.6 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 1) MetallophosN PF16371.5 OAG43014.1 - 0.072 13.4 0.1 1.5 9.1 0.1 2.4 1 1 1 2 2 2 0 N terminal of Calcineurin-like phosphoesterase Cu-oxidase_3 PF07732.15 OAG43015.1 - 1.9e-36 124.6 0.2 6.1e-34 116.6 0.0 3.4 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 OAG43015.1 - 1.6e-34 118.6 3.4 1.1e-33 115.9 0.5 3.1 2 2 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.22 OAG43015.1 - 9.4e-16 58.3 0.0 2.9e-15 56.7 0.0 1.8 2 0 0 2 2 2 1 Multicopper oxidase Phosphoesterase PF04185.14 OAG43016.1 - 5.3e-73 246.3 4.5 7.3e-73 245.8 4.5 1.1 1 0 0 1 1 1 1 Phosphoesterase family RicinB_lectin_2 PF14200.6 OAG43016.1 - 0.019 15.7 0.0 0.1 13.3 0.0 2.3 1 0 0 1 1 1 0 Ricin-type beta-trefoil lectin domain-like MYT1 PF08474.11 OAG43016.1 - 0.15 12.0 0.1 0.23 11.3 0.1 1.2 1 0 0 1 1 1 0 Myelin transcription factor 1 Fungal_trans_2 PF11951.8 OAG43018.1 - 0.001 18.0 0.4 0.0016 17.3 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Abhydrolase_6 PF12697.7 OAG43019.1 - 1.6e-08 35.4 1.3 2.6e-08 34.8 1.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAG43019.1 - 8.8e-06 25.6 0.1 1.5e-05 24.8 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAG43019.1 - 8.4e-05 21.9 0.1 0.00028 20.2 0.1 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 OAG43019.1 - 0.022 14.3 0.1 0.27 10.7 0.0 2.4 2 1 0 2 2 2 0 Prolyl oligopeptidase family Ysc84 PF04366.12 OAG43020.1 - 5.4e-38 129.6 0.3 8.6e-38 129.0 0.3 1.3 1 0 0 1 1 1 1 Las17-binding protein actin regulator Hydrophobin_2 PF06766.11 OAG43021.1 - 2.5e-09 36.9 2.2 3.5e-08 33.3 1.2 2.3 2 0 0 2 2 2 2 Fungal hydrophobin E1-E2_ATPase PF00122.20 OAG43022.1 - 1.6e-24 86.4 2.2 1.6e-24 86.4 2.2 3.1 2 2 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 OAG43022.1 - 4.4e-24 85.9 4.5 1.1e-23 84.6 1.4 2.6 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 OAG43022.1 - 5.6e-10 39.5 0.7 1.7e-09 38.0 0.0 2.1 2 0 0 2 2 2 1 Heavy-metal-associated domain MFS_1 PF07690.16 OAG43023.1 - 8.5e-32 110.4 28.3 1.2e-31 109.9 28.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Wzz PF02706.15 OAG43023.1 - 0.31 11.3 1.2 2.9 8.2 0.0 3.1 3 0 0 3 3 3 0 Chain length determinant protein FAD_binding_3 PF01494.19 OAG43024.1 - 4.3e-15 55.8 0.0 1.3e-14 54.2 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 OAG43024.1 - 6.7e-09 35.4 0.7 0.0002 20.7 0.0 3.0 3 1 1 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAG43024.1 - 2.6e-08 33.4 0.2 5.7e-08 32.3 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 OAG43024.1 - 2.8e-08 33.7 0.3 0.00016 21.4 0.0 2.7 3 0 0 3 3 3 2 FAD dependent oxidoreductase HI0933_like PF03486.14 OAG43024.1 - 4.4e-07 28.9 0.2 3.1e-05 22.8 0.0 2.2 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 OAG43024.1 - 4.9e-06 26.2 0.1 9.3e-06 25.2 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAG43024.1 - 2e-05 24.7 0.0 0.00012 22.2 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 OAG43024.1 - 8.3e-05 23.1 0.6 0.01 16.4 0.1 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OAG43024.1 - 0.00016 20.9 0.0 0.00026 20.2 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 OAG43024.1 - 0.0042 16.4 0.3 0.017 14.4 0.2 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OAG43024.1 - 0.034 13.2 0.2 0.16 11.0 0.1 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 OAG43024.1 - 0.048 12.9 0.0 0.084 12.2 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 OAG43024.1 - 0.06 12.6 0.1 0.13 11.5 0.1 1.5 1 0 0 1 1 1 0 Thi4 family p450 PF00067.22 OAG43025.1 - 1.3e-73 248.4 0.0 1.6e-73 248.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 bVLRF1 PF18826.1 OAG43026.1 - 9.8e-60 200.7 0.0 9.8e-60 200.7 0.0 3.1 3 1 1 4 4 4 1 bacteroidetes VLRF1 release factor Ank_5 PF13857.6 OAG43026.1 - 4.2e-08 33.3 0.1 9.9e-08 32.1 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) PARP PF00644.20 OAG43027.1 - 4.4e-57 192.8 0.1 2.5e-56 190.4 0.0 2.0 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 OAG43027.1 - 1.8e-41 141.4 2.3 4.3e-41 140.2 0.6 2.1 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 OAG43027.1 - 1.5e-19 69.8 0.7 3e-19 68.9 0.7 1.5 1 0 0 1 1 1 1 WGR domain BRCT_2 PF16589.5 OAG43027.1 - 0.0047 17.3 0.0 0.01 16.2 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain GRP PF07172.11 OAG43028.1 - 0.8 10.4 19.7 0.78 10.5 11.6 2.7 3 0 0 3 3 3 0 Glycine rich protein family DUF1631 PF07793.11 OAG43028.1 - 9.3 4.5 10.6 6.1 5.1 9.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1631) DER1 PF04511.15 OAG43029.1 - 1.4e-23 83.8 5.0 3.2e-11 43.5 1.3 2.1 2 0 0 2 2 2 2 Der1-like family TruB_N PF01509.18 OAG43030.1 - 2.7e-23 83.0 0.2 2.6e-20 73.3 0.2 3.3 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 OAG43030.1 - 6.9e-23 80.6 1.0 1.2e-22 79.8 1.0 1.4 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain PUA PF01472.20 OAG43030.1 - 5.4e-21 74.3 1.3 1e-20 73.4 1.3 1.5 1 0 0 1 1 1 1 PUA domain UPF0113 PF03657.13 OAG43030.1 - 0.0072 16.6 0.0 0.02 15.2 0.0 1.7 1 0 0 1 1 1 1 UPF0113 PUA domain DKCLD PF08068.12 OAG43030.1 - 0.17 11.9 0.5 8.1 6.6 0.3 2.9 2 1 1 3 3 3 0 DKCLD (NUC011) domain RNA_polI_A34 PF08208.11 OAG43030.1 - 1.2 9.2 24.9 1.8 8.6 24.9 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 RR_TM4-6 PF06459.12 OAG43030.1 - 6.1 6.6 14.8 8.1 6.2 14.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Pkinase PF00069.25 OAG43031.1 - 6.7e-48 163.4 0.0 1.1e-47 162.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG43031.1 - 3.1e-26 92.2 0.0 4.5e-26 91.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OAG43031.1 - 0.0073 15.7 0.0 0.016 14.6 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OAG43031.1 - 0.028 13.7 0.0 0.052 12.9 0.0 1.3 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 OAG43031.1 - 0.051 13.5 0.6 2.4 8.0 0.0 3.1 2 1 1 3 3 3 0 Phosphotransferase enzyme family BAR PF03114.18 OAG43032.1 - 4e-59 200.2 1.4 5.4e-59 199.7 1.4 1.1 1 0 0 1 1 1 1 BAR domain CP12 PF02672.15 OAG43032.1 - 0.039 14.7 0.1 0.15 12.8 0.0 2.1 2 0 0 2 2 2 0 CP12 domain FliD_N PF02465.18 OAG43032.1 - 0.19 12.5 2.7 4.9 7.9 0.6 2.4 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus ETF PF01012.21 OAG43033.1 - 3.5e-45 154.1 0.9 4.2e-45 153.9 0.9 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Skp1 PF01466.19 OAG43034.1 - 2.8e-28 97.8 0.5 4.9e-28 97.0 0.5 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 OAG43034.1 - 7.9e-24 83.6 0.5 1.8e-23 82.5 0.3 1.7 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain Amidase PF01425.21 OAG43036.1 - 3.4e-83 280.1 0.0 1.1e-82 278.5 0.0 1.7 1 1 0 1 1 1 1 Amidase Ribosomal_L16 PF00252.18 OAG43036.1 - 0.11 12.5 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L16p/L10e MFS_1 PF07690.16 OAG43037.1 - 5.5e-22 78.2 19.0 5.5e-22 78.2 19.0 2.5 2 1 1 3 3 3 2 Major Facilitator Superfamily DUF1772 PF08592.11 OAG43037.1 - 0.017 15.4 0.2 0.017 15.4 0.2 3.9 3 2 1 4 4 4 0 Domain of unknown function (DUF1772) AP3D1 PF06375.11 OAG43037.1 - 0.38 11.0 26.7 0.76 10.0 26.7 1.5 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 SR-25 PF10500.9 OAG43037.1 - 1.3 8.6 33.4 2 8.0 33.4 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Zip PF02535.22 OAG43037.1 - 1.8 7.7 6.2 7.3 5.7 2.9 2.7 3 0 0 3 3 3 0 ZIP Zinc transporter PcfK PF14058.6 OAG43037.1 - 3 8.1 21.7 5.6 7.2 21.7 1.5 1 0 0 1 1 1 0 PcfK-like protein DUF1168 PF06658.12 OAG43037.1 - 3.9 7.3 30.0 6.2 6.6 30.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) DDHD PF02862.17 OAG43037.1 - 6.3 6.9 8.1 11 6.1 8.1 1.4 1 0 0 1 1 1 0 DDHD domain DUF3807 PF12720.7 OAG43037.1 - 9 6.5 18.7 16 5.7 18.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Fungal_trans_2 PF11951.8 OAG43038.1 - 4.2e-05 22.5 0.2 5.5e-05 22.1 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cnd2 PF05786.14 OAG43039.1 - 4.2e-247 822.7 9.5 5.2e-247 822.4 9.5 1.0 1 0 0 1 1 1 1 Condensin complex subunit 2 CNDH2_N PF06278.11 OAG43039.1 - 0.18 12.0 0.7 0.54 10.5 0.0 2.2 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal EF-hand_4 PF12763.7 OAG43040.1 - 9.5e-24 83.3 0.0 6.9e-12 45.2 0.0 2.4 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand WH2 PF02205.20 OAG43040.1 - 1.2e-06 28.2 0.7 3.1e-06 26.8 0.7 1.8 1 0 0 1 1 1 1 WH2 motif DUF1720 PF08226.11 OAG43040.1 - 7.8e-06 26.2 31.1 7.8e-06 26.2 31.1 8.2 6 2 2 8 8 8 3 Domain of unknown function (DUF1720) EF-hand_7 PF13499.6 OAG43040.1 - 7.2e-05 23.2 0.0 0.017 15.6 0.0 2.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 OAG43040.1 - 0.00076 18.9 0.0 0.13 11.8 0.0 2.5 2 0 0 2 2 2 2 EF hand Fungal_trans PF04082.18 OAG43041.1 - 5.2e-15 55.2 0.2 2.4e-14 53.0 0.1 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG43041.1 - 7.4e-06 26.0 13.4 1.6e-05 24.9 13.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FMO-like PF00743.19 OAG43042.1 - 4.1e-16 58.5 0.0 8.9e-16 57.4 0.0 1.5 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 OAG43042.1 - 4.3e-14 52.4 0.0 1.1e-12 47.8 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG43042.1 - 1.5e-10 41.1 0.0 6.3e-07 29.5 0.0 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 OAG43042.1 - 2.3e-08 33.6 0.0 1.6e-07 30.8 0.0 1.9 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 OAG43042.1 - 3.9e-08 32.9 0.0 1.4e-07 31.1 0.0 1.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAG43042.1 - 1.5e-05 25.4 0.1 0.012 16.2 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAG43042.1 - 1.6e-05 25.0 0.0 0.0014 18.7 0.0 2.8 2 1 0 2 2 2 1 FAD-NAD(P)-binding TrkA_N PF02254.18 OAG43042.1 - 0.00065 19.9 0.1 0.15 12.4 0.0 3.2 4 0 0 4 4 3 1 TrkA-N domain Shikimate_DH PF01488.20 OAG43042.1 - 0.0029 17.7 0.0 0.092 12.8 0.0 2.2 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 OAG43042.1 - 0.0038 17.7 0.0 2.8 8.4 0.0 2.6 2 1 0 2 2 2 1 Putative NAD(P)-binding Thi4 PF01946.17 OAG43042.1 - 0.016 14.5 0.0 0.4 9.9 0.0 2.2 2 0 0 2 2 2 0 Thi4 family 2-Hacid_dh_C PF02826.19 OAG43042.1 - 0.023 14.1 0.0 0.049 13.0 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF1188 PF06690.11 OAG43042.1 - 0.023 14.2 0.0 3.1 7.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1188) FAD_binding_3 PF01494.19 OAG43042.1 - 0.028 13.7 0.0 4.4 6.4 0.0 2.3 2 0 0 2 2 2 0 FAD binding domain IlvN PF07991.12 OAG43042.1 - 0.058 13.0 0.2 0.57 9.7 0.0 2.1 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Lycopene_cycl PF05834.12 OAG43042.1 - 0.13 11.3 0.0 6.7 5.6 0.0 2.7 3 0 0 3 3 3 0 Lycopene cyclase protein DUF3288 PF11691.8 OAG43042.1 - 0.17 11.9 1.0 0.37 10.9 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3288) NAD_Gly3P_dh_N PF01210.23 OAG43042.1 - 0.19 11.7 0.0 0.32 11.0 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.16 OAG43042.1 - 0.2 11.3 0.0 1.5 8.5 0.0 2.1 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA RNA_pol_L_2 PF13656.6 OAG43043.1 - 2e-24 85.1 0.1 3.9e-24 84.2 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 OAG43043.1 - 1.7e-09 37.0 0.0 4e-09 35.8 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain NMO PF03060.15 OAG43044.1 - 1.6e-31 109.9 8.5 3e-27 95.9 3.2 2.3 2 1 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.18 OAG43044.1 - 1.4e-10 40.7 0.6 2e-10 40.3 0.6 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 OAG43044.1 - 1.6e-10 40.5 0.2 6.1e-10 38.6 0.1 1.8 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 OAG43044.1 - 7.7e-05 22.0 0.3 0.00013 21.3 0.3 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.21 OAG43044.1 - 0.028 13.9 0.0 0.076 12.5 0.0 1.7 1 0 0 1 1 1 0 Histidine biosynthesis protein ThiG PF05690.14 OAG43044.1 - 0.099 11.9 0.1 0.19 11.0 0.1 1.4 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG Vps16_C PF04840.12 OAG43044.1 - 0.25 10.3 0.0 0.41 9.6 0.0 1.2 1 0 0 1 1 1 0 Vps16, C-terminal region Lipase_3 PF01764.25 OAG43045.1 - 2.4e-29 102.0 0.0 4.8e-29 101.0 0.0 1.5 1 1 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 OAG43045.1 - 0.00036 21.2 0.1 0.00059 20.5 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG43045.1 - 0.0044 16.3 0.0 0.0075 15.6 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 OAG43045.1 - 0.018 15.1 0.0 0.035 14.2 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain PGAP1 PF07819.13 OAG43045.1 - 0.042 13.5 0.0 0.066 12.9 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein DUF2974 PF11187.8 OAG43045.1 - 0.15 11.6 0.0 0.74 9.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Abhydrolase_5 PF12695.7 OAG43045.1 - 0.25 11.1 0.0 0.42 10.3 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family NGP1NT PF08153.12 OAG43046.1 - 1.7e-50 170.5 1.1 2.7e-50 169.9 1.1 1.3 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 OAG43046.1 - 8.6e-18 64.5 0.0 3.6e-14 52.8 0.0 2.9 2 1 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 OAG43046.1 - 1.1e-05 25.0 0.0 0.00016 21.3 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B Arf PF00025.21 OAG43046.1 - 0.00035 20.1 0.0 0.1 12.1 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OAG43046.1 - 0.00055 19.9 0.0 0.0014 18.5 0.0 1.6 1 1 0 1 1 1 1 RsgA GTPase Dynamin_N PF00350.23 OAG43046.1 - 0.0026 17.8 0.4 0.76 9.8 0.0 3.8 3 1 1 4 4 4 1 Dynamin family GTP_EFTU PF00009.27 OAG43046.1 - 0.0042 16.6 0.0 0.33 10.5 0.0 3.0 2 1 1 3 3 3 1 Elongation factor Tu GTP binding domain Ank_2 PF12796.7 OAG43048.1 - 7.4e-21 74.5 0.2 6e-11 42.8 0.0 3.2 3 0 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OAG43048.1 - 1.4e-19 68.1 0.3 0.028 14.9 0.0 6.3 6 0 0 6 6 6 5 Ankyrin repeat Ank PF00023.30 OAG43048.1 - 7.1e-18 64.2 2.4 0.00066 20.0 0.0 5.5 5 1 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.6 OAG43048.1 - 3.4e-17 62.6 0.5 0.00022 21.7 0.0 5.8 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 OAG43048.1 - 3.3e-15 56.0 1.5 0.00032 20.9 0.0 4.8 3 1 3 6 6 6 5 Ankyrin repeats (many copies) Abhydrolase_1 PF00561.20 OAG43049.1 - 4.8e-22 78.8 0.1 8.2e-22 78.1 0.1 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 OAG43049.1 - 3.6e-19 68.8 0.0 1.3e-18 67.0 0.0 1.9 2 0 0 2 2 2 1 TAP-like protein DUF4949 PF16307.5 OAG43049.1 - 0.015 15.4 0.1 0.028 14.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4949) YuzL PF14115.6 OAG43050.1 - 2.1 8.9 7.3 0.76 10.3 3.8 2.1 1 1 1 2 2 2 0 YuzL-like protein MGC-24 PF05283.11 OAG43050.1 - 9.6 6.7 13.4 29 5.1 13.4 1.7 1 1 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Zn_clus PF00172.18 OAG43051.1 - 0.0058 16.7 2.8 0.011 15.8 2.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Bacteriocin_IIi PF11758.8 OAG43053.1 - 9.8 6.1 8.6 1.1 9.1 0.8 3.0 3 0 0 3 3 3 0 Aureocin-like type II bacteriocin FMO-like PF00743.19 OAG43054.1 - 2e-13 49.6 0.2 3.7e-12 45.5 0.2 2.3 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OAG43054.1 - 4.8e-13 49.0 0.0 1.7e-11 44.0 0.0 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG43054.1 - 1.4e-11 44.5 0.0 6.7e-11 42.3 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAG43054.1 - 1.8e-11 43.8 0.0 1.4e-07 31.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAG43054.1 - 7e-08 32.4 0.1 3.1e-06 27.0 0.1 2.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 OAG43054.1 - 1.7e-06 27.5 0.0 0.0031 16.7 0.0 3.3 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 OAG43054.1 - 0.00058 19.9 0.0 0.058 13.4 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding Amino_oxidase PF01593.24 OAG43054.1 - 0.0033 16.8 0.0 0.0051 16.1 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Thi4 PF01946.17 OAG43054.1 - 0.019 14.2 0.3 0.078 12.2 0.0 2.1 3 0 0 3 3 3 0 Thi4 family Pyr_redox PF00070.27 OAG43054.1 - 0.097 13.2 0.0 1.1 9.9 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Iso_dh PF00180.20 OAG43055.1 - 1.3e-85 287.7 0.0 1.5e-85 287.4 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Fungal_trans PF04082.18 OAG43056.1 - 2.9e-18 65.9 0.1 4.7e-18 65.2 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG43056.1 - 1.2e-07 31.8 5.4 2e-07 31.0 5.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Transketolase_C PF02780.20 OAG43057.1 - 1.2e-11 44.6 0.0 1.6e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 Transketolase, C-terminal domain adh_short_C2 PF13561.6 OAG43058.1 - 6.6e-62 209.1 0.9 7.8e-62 208.9 0.9 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG43058.1 - 1.9e-54 184.1 0.6 2.3e-54 183.8 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG43058.1 - 2.4e-14 53.6 0.8 3.8e-14 53.0 0.8 1.2 1 0 0 1 1 1 1 KR domain DUF1598 PF07643.11 OAG43058.1 - 0.02 15.1 0.0 7.2 6.9 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1598) THF_DHG_CYH_C PF02882.19 OAG43058.1 - 0.049 12.9 0.1 0.11 11.9 0.1 1.6 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF3563 PF12086.8 OAG43058.1 - 0.1 12.4 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3563) Methyltransf_PK PF05891.12 OAG43058.1 - 0.16 11.4 0.1 0.24 10.9 0.1 1.2 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Sugar_tr PF00083.24 OAG43059.1 - 7.5e-103 344.8 23.0 9.2e-103 344.5 23.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG43059.1 - 1e-23 83.9 54.5 7.3e-21 74.5 23.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG43060.1 - 2.1e-102 343.3 17.7 2.5e-102 343.1 17.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG43060.1 - 1.3e-25 90.1 30.9 1.3e-25 90.1 15.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 OAG43060.1 - 0.0026 16.2 0.8 0.0026 16.2 0.8 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF2530 PF10745.9 OAG43060.1 - 0.15 12.3 6.3 0.099 12.9 1.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) DUF3188 PF11384.8 OAG43060.1 - 2.2 8.1 6.6 0.91 9.3 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3188) Aldedh PF00171.22 OAG43061.1 - 2.5e-158 527.4 0.9 2.8e-158 527.3 0.9 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Abhydrolase_1 PF00561.20 OAG43062.1 - 3.8e-22 79.2 0.3 9.9e-22 77.8 0.1 1.8 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG43062.1 - 8.2e-17 62.5 0.0 1.1e-16 62.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG43062.1 - 8.3e-12 44.9 0.1 1.4e-11 44.1 0.1 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Acyl_transf_2 PF02273.15 OAG43062.1 - 0.00037 19.8 0.0 0.00059 19.2 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase DLH PF01738.18 OAG43062.1 - 0.0015 18.2 0.1 0.0077 15.8 0.0 2.2 2 2 1 3 3 3 1 Dienelactone hydrolase family Ndr PF03096.14 OAG43062.1 - 0.0027 16.4 0.0 0.0055 15.5 0.0 1.4 1 1 0 1 1 1 1 Ndr family Chlorophyllase2 PF12740.7 OAG43062.1 - 0.02 13.8 0.0 0.034 13.1 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Chlorophyllase PF07224.11 OAG43062.1 - 0.022 13.8 0.1 0.029 13.4 0.1 1.2 1 0 0 1 1 1 0 Chlorophyllase Metallophos PF00149.28 OAG43063.1 - 2.5e-12 47.7 0.3 4.3e-12 47.0 0.3 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OAG43063.1 - 0.15 12.2 0.0 5.7 7.1 0.0 2.4 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Stk19 PF10494.9 OAG43065.1 - 2.2e-80 269.9 0.0 2.9e-80 269.5 0.0 1.1 1 0 0 1 1 1 1 Serine-threonine protein kinase 19 Glyco_transf_20 PF00982.21 OAG43066.1 - 1.3e-162 541.8 0.2 1.8e-162 541.4 0.2 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 OAG43066.1 - 1.9e-36 125.4 0.0 4.1e-36 124.3 0.0 1.5 1 0 0 1 1 1 1 Trehalose-phosphatase DUF2487 PF10673.9 OAG43066.1 - 0.023 14.7 0.0 0.084 12.9 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2487) Glyco_transf_5 PF08323.11 OAG43066.1 - 0.049 13.3 0.3 0.12 12.0 0.3 1.6 1 0 0 1 1 1 0 Starch synthase catalytic domain GFO_IDH_MocA PF01408.22 OAG43067.1 - 1.8e-18 67.5 0.0 4.4e-18 66.2 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Zn_clus PF00172.18 OAG43068.1 - 3.2e-06 27.2 6.7 6e-06 26.3 6.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GCK PF07802.11 OAG43068.1 - 0.2 12.1 0.0 0.47 10.9 0.0 1.6 1 0 0 1 1 1 0 GCK domain FAD_binding_4 PF01565.23 OAG43070.1 - 2.9e-26 91.9 1.5 5.4e-26 91.0 1.5 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 OAG43070.1 - 1.9e-05 24.7 0.0 3.9e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like EthD PF07110.11 OAG43071.1 - 2.7e-12 47.7 0.1 3.7e-12 47.2 0.1 1.2 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 OAG43071.1 - 6.8e-06 26.5 0.2 8.4e-06 26.2 0.2 1.1 1 0 0 1 1 1 1 Methylmuconolactone methyl-isomerase DUF2235 PF09994.9 OAG43072.1 - 9.5e-41 140.0 0.0 1.4e-40 139.5 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) MMR_HSR1 PF01926.23 OAG43072.1 - 0.00048 20.2 0.0 0.0011 19.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase VSP PF03302.13 OAG43072.1 - 0.016 14.1 4.0 0.026 13.4 4.0 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein DUF35_N PF12172.8 OAG43072.1 - 0.11 12.4 1.1 0.24 11.3 1.1 1.5 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) FlgD_ig PF13860.6 OAG43074.1 - 0.072 13.0 0.1 17 5.4 0.0 3.7 4 0 0 4 4 4 0 FlgD Ig-like domain CDH-cyt PF16010.5 OAG43075.1 - 4.1e-43 147.2 0.0 5.3e-43 146.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase adh_short_C2 PF13561.6 OAG43076.1 - 2.5e-13 50.2 0.4 9.3e-12 45.0 0.4 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG43076.1 - 6.2e-12 45.4 0.1 6.7e-11 42.0 0.1 2.1 1 1 0 1 1 1 1 short chain dehydrogenase FMO-like PF00743.19 OAG43077.1 - 2.4e-17 62.6 0.0 4.8e-17 61.6 0.0 1.4 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OAG43077.1 - 1.6e-10 40.8 0.0 7.4e-09 35.3 0.0 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG43077.1 - 1.3e-09 38.1 0.0 6.3e-09 35.9 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 OAG43077.1 - 3.6e-08 32.9 0.1 9.2e-07 28.3 0.0 2.3 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 OAG43077.1 - 1.6e-07 30.9 0.0 3.7e-06 26.4 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAG43077.1 - 0.0001 22.3 0.1 0.042 13.9 0.1 3.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.24 OAG43077.1 - 0.0013 18.4 0.0 0.17 11.5 0.0 2.7 2 1 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 OAG43077.1 - 0.002 17.4 0.0 0.76 9.0 0.0 2.3 2 0 0 2 2 2 2 Thi4 family Amino_oxidase PF01593.24 OAG43077.1 - 0.015 14.6 0.0 0.35 10.1 0.0 2.6 2 1 1 3 3 3 0 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 OAG43077.1 - 0.016 15.7 0.0 3.5 8.3 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 OAG43078.1 - 9.6e-11 40.8 0.0 3e-10 39.1 0.0 1.7 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 OAG43078.1 - 1.7e-10 40.7 0.0 2.8e-09 36.6 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG43078.1 - 7.5e-07 28.6 0.0 1.5e-05 24.4 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 OAG43078.1 - 8.9e-07 28.4 0.0 3.8e-06 26.4 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG43078.1 - 1.1e-06 28.8 0.0 0.00016 21.9 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 OAG43078.1 - 0.035 14.1 0.7 2.8 7.9 0.0 3.4 3 1 0 3 3 3 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 OAG43078.1 - 0.073 13.6 0.0 6 7.5 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF1033 PF06279.11 OAG43078.1 - 0.26 11.5 3.0 0.62 10.3 3.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1033) ADH_zinc_N PF00107.26 OAG43079.1 - 6.1e-17 61.8 0.1 1.9e-16 60.2 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG43079.1 - 2.1e-15 56.6 6.8 2.1e-15 56.6 6.8 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain SnoaL PF07366.12 OAG43079.1 - 6.8e-06 25.9 0.1 4.4e-05 23.3 0.1 2.2 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 OAG43079.1 - 0.00051 20.6 0.0 0.0013 19.4 0.0 1.7 2 0 0 2 2 2 1 SnoaL-like domain ADH_zinc_N_2 PF13602.6 OAG43079.1 - 0.12 13.4 0.0 0.25 12.4 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Sugar_tr PF00083.24 OAG43080.1 - 1.5e-77 261.4 20.9 8.7e-77 258.9 20.9 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG43080.1 - 1.5e-22 80.0 35.0 2.7e-13 49.6 10.4 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily DUF2370 PF10176.9 OAG43080.1 - 2.7 7.6 3.8 7.1 6.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2370) Epimerase PF01370.21 OAG43081.1 - 3e-14 53.1 0.0 4.5e-14 52.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OAG43081.1 - 1.9e-10 40.2 0.0 3e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 OAG43081.1 - 4e-08 32.7 0.0 5.1e-07 29.1 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 OAG43081.1 - 8.6e-07 28.7 0.0 1.9e-06 27.5 0.0 1.6 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase KR PF08659.10 OAG43081.1 - 4.1e-06 26.8 0.0 7.3e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 OAG43081.1 - 3.8e-05 23.6 0.0 6.8e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 OAG43081.1 - 0.0015 18.2 0.1 0.073 12.6 0.2 2.6 2 1 0 2 2 2 1 NmrA-like family adh_short PF00106.25 OAG43081.1 - 0.0034 16.9 0.0 0.0064 16.0 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.15 OAG43081.1 - 0.045 12.9 0.0 0.068 12.3 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Shikimate_DH PF01488.20 OAG43081.1 - 0.15 12.1 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.21 OAG43082.1 - 0.00011 21.8 0.0 0.00016 21.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 OAG43082.1 - 0.045 14.2 0.0 0.079 13.4 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain adh_short_C2 PF13561.6 OAG43083.1 - 1.9e-43 148.7 0.0 2.3e-43 148.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG43083.1 - 3.3e-26 91.9 0.1 4e-26 91.7 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase IreB PF06135.12 OAG43083.1 - 0.15 12.3 0.0 0.31 11.3 0.0 1.5 1 0 0 1 1 1 0 IreB regulatory phosphoprotein G3P_antiterm PF04309.12 OAG43083.1 - 0.16 11.4 0.1 0.36 10.2 0.0 1.6 1 1 0 1 1 1 0 Glycerol-3-phosphate responsive antiterminator adh_short_C2 PF13561.6 OAG43084.1 - 2.9e-56 190.7 0.9 5.4e-55 186.5 0.9 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG43084.1 - 1.2e-41 142.4 0.2 3.2e-41 141.0 0.2 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG43084.1 - 1.7e-11 44.4 0.3 4.9e-11 42.9 0.3 1.8 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG43084.1 - 0.028 13.9 0.1 0.16 11.4 0.0 2.2 2 1 1 3 3 3 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 OAG43084.1 - 0.059 12.5 0.0 0.085 12.0 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Phage_attach PF05354.11 OAG43084.1 - 0.1 12.5 0.1 0.24 11.3 0.1 1.6 1 0 0 1 1 1 0 Phage Head-Tail Attachment Ldh_1_N PF00056.23 OAG43084.1 - 0.11 12.6 0.1 0.2 11.8 0.1 1.3 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Fungal_trans PF04082.18 OAG43085.1 - 1.8e-11 43.6 0.3 3.5e-11 42.6 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG43085.1 - 0.00058 19.9 5.0 0.0013 18.9 5.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain APH PF01636.23 OAG43088.1 - 4.1e-15 56.4 0.1 2.7e-14 53.7 0.0 2.3 2 2 1 3 3 3 1 Phosphotransferase enzyme family 4HBT_3 PF13622.6 OAG43089.1 - 3.9e-51 174.7 0.1 4.5e-51 174.5 0.1 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Na_Ca_ex PF01699.24 OAG43090.1 - 8e-52 175.2 42.8 2.8e-28 98.8 19.1 3.1 3 0 0 3 3 3 2 Sodium/calcium exchanger protein Vpu PF00558.19 OAG43090.1 - 0.11 12.3 0.0 0.3 10.9 0.0 1.7 1 0 0 1 1 1 0 Vpu protein Phage_holin_Dp1 PF16938.5 OAG43090.1 - 0.41 10.9 4.1 12 6.2 0.1 2.8 2 0 0 2 2 2 0 Putative phage holin Dp-1 AMP-binding PF00501.28 OAG43091.1 - 2.8e-89 299.7 0.0 3.4e-89 299.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG43091.1 - 1.6e-12 48.2 0.1 3.5e-12 47.1 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Formyl_trans_N PF00551.19 OAG43092.1 - 4.5e-39 134.0 0.0 6.4e-39 133.6 0.0 1.1 1 0 0 1 1 1 1 Formyl transferase Epimerase PF01370.21 OAG43093.1 - 1.5e-10 40.9 0.0 2.5e-10 40.3 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 OAG43093.1 - 0.00093 18.4 0.0 0.0033 16.6 0.0 1.8 2 0 0 2 2 2 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 OAG43093.1 - 0.006 15.8 0.0 0.042 13.0 0.0 2.0 2 0 0 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.6 OAG43093.1 - 0.014 15.3 0.0 0.021 14.7 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding NmrA PF05368.13 OAG43093.1 - 0.035 13.6 0.0 0.052 13.1 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family adh_short PF00106.25 OAG43093.1 - 0.05 13.1 0.0 0.079 12.4 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase GDP_Man_Dehyd PF16363.5 OAG43093.1 - 0.058 12.8 0.0 0.12 11.8 0.0 1.5 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase C2 PF00168.30 OAG43094.1 - 8.2e-10 38.9 0.0 1.6e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 C2 domain AAA PF00004.29 OAG43095.1 - 2.2e-13 50.8 0.0 5.4e-13 49.5 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OAG43095.1 - 1.3e-11 45.1 0.4 4.4e-11 43.4 0.1 2.0 2 1 0 2 2 1 1 AAA ATPase domain AAA_22 PF13401.6 OAG43095.1 - 3.4e-09 37.1 0.1 1.2e-08 35.3 0.0 1.9 2 0 0 2 2 1 1 AAA domain Cdc6_C PF09079.11 OAG43095.1 - 5.1e-07 29.6 0.0 2e-06 27.7 0.0 2.1 1 1 0 1 1 1 1 CDC6, C terminal winged helix domain AAA_7 PF12775.7 OAG43095.1 - 0.0004 19.9 0.1 0.00077 19.0 0.1 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region NACHT PF05729.12 OAG43095.1 - 0.00055 19.9 0.1 0.0012 18.8 0.1 1.6 1 0 0 1 1 1 1 NACHT domain AAA_19 PF13245.6 OAG43095.1 - 0.00078 19.8 0.2 0.0043 17.4 0.1 2.2 2 1 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 OAG43095.1 - 0.0018 18.0 0.0 0.0042 16.8 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.14 OAG43095.1 - 0.0035 17.3 0.0 0.015 15.3 0.0 2.1 2 0 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 OAG43095.1 - 0.0042 17.1 0.0 0.0088 16.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 OAG43095.1 - 0.0052 17.2 0.1 0.018 15.4 0.0 1.9 2 0 0 2 2 2 1 RNA helicase TsaE PF02367.17 OAG43095.1 - 0.0054 16.7 0.1 0.01 15.8 0.1 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE PIF1 PF05970.14 OAG43095.1 - 0.0085 15.3 0.0 0.014 14.6 0.0 1.3 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 OAG43095.1 - 0.013 15.3 0.0 0.026 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 OAG43095.1 - 0.017 14.9 0.0 0.037 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 OAG43095.1 - 0.024 13.8 0.0 0.047 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) TIP49 PF06068.13 OAG43095.1 - 0.037 13.2 0.1 0.061 12.5 0.1 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain Rad17 PF03215.15 OAG43095.1 - 0.041 13.8 0.1 0.2 11.6 0.1 2.0 1 1 0 1 1 1 0 Rad17 P-loop domain AAA_lid_10 PF17872.1 OAG43095.1 - 0.049 13.8 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA lid domain AAA_33 PF13671.6 OAG43095.1 - 0.052 13.7 0.0 0.15 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 OAG43095.1 - 0.052 13.3 0.0 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase T2SSE PF00437.20 OAG43095.1 - 0.072 12.1 0.1 0.12 11.4 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein ABC_tran PF00005.27 OAG43095.1 - 0.098 13.2 0.3 0.6 10.6 0.1 2.4 3 0 0 3 3 2 0 ABC transporter AAA_29 PF13555.6 OAG43095.1 - 0.11 12.3 0.0 0.33 10.7 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain NTPase_1 PF03266.15 OAG43095.1 - 0.15 12.0 0.0 0.36 10.7 0.0 1.6 1 1 0 1 1 1 0 NTPase RuvB_N PF05496.12 OAG43095.1 - 0.16 11.7 0.0 0.97 9.2 0.0 2.1 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain ATPase_2 PF01637.18 OAG43095.1 - 0.21 11.5 0.0 0.48 10.3 0.0 1.6 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea Thioredoxin_7 PF13899.6 OAG43096.1 - 1.4e-18 66.8 0.1 2.9e-18 65.8 0.1 1.5 1 0 0 1 1 1 1 Thioredoxin-like UBA_4 PF14555.6 OAG43096.1 - 4.3e-09 36.0 0.0 1e-08 34.8 0.0 1.7 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 OAG43096.1 - 2.6e-07 30.8 0.0 7.7e-07 29.2 0.0 1.8 1 0 0 1 1 1 1 UBX domain Thioredoxin_2 PF13098.6 OAG43096.1 - 0.013 16.0 0.0 0.029 14.8 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like domain UIM PF02809.20 OAG43096.1 - 0.013 15.4 2.2 0.013 15.4 2.2 2.2 2 0 0 2 2 2 0 Ubiquitin interaction motif Sugarporin_N PF11471.8 OAG43096.1 - 0.037 14.0 0.0 0.088 12.8 0.0 1.6 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension Thioredox_DsbH PF03190.15 OAG43096.1 - 0.082 12.9 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF255 Pkinase PF00069.25 OAG43097.1 - 7.5e-69 232.0 0.0 1.3e-68 231.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG43097.1 - 2.4e-51 174.5 0.0 4e-51 173.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAG43097.1 - 0.00028 19.8 0.0 0.00069 18.5 0.0 1.6 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 OAG43097.1 - 0.0011 18.3 0.0 0.097 12.0 0.0 2.4 2 0 0 2 2 2 2 Kinase-like HTH_35 PF13693.6 OAG43097.1 - 0.13 12.3 0.5 0.31 11.1 0.5 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding DUF3074 PF11274.8 OAG43098.1 - 1e-45 156.0 0.1 1.3e-45 155.6 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) Peptidase_S8 PF00082.22 OAG43099.1 - 1.2e-40 139.7 0.0 2.6e-40 138.6 0.0 1.5 1 1 0 1 1 1 1 Subtilase family p450 PF00067.22 OAG43100.1 - 4.3e-58 197.2 0.0 5.5e-58 196.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF4538 PF15061.6 OAG43100.1 - 0.055 13.2 0.7 0.12 12.1 0.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4538) NAD_binding_2 PF03446.15 OAG43101.1 - 7.2e-33 114.0 0.0 9.5e-33 113.6 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 OAG43101.1 - 5.3e-20 71.9 0.0 1.1e-19 70.9 0.0 1.6 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 OAG43101.1 - 0.0035 17.9 0.0 0.014 16.0 0.0 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 OAG43101.1 - 0.023 14.1 0.0 0.035 13.5 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 OAG43101.1 - 0.046 13.3 0.0 0.1 12.2 0.0 1.5 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Shikimate_DH PF01488.20 OAG43101.1 - 0.13 12.3 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase CMD PF02627.20 OAG43102.1 - 1.2e-21 76.6 0.2 2.5e-21 75.5 0.1 1.6 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family APH PF01636.23 OAG43103.1 - 6.2e-12 46.0 0.0 9.4e-11 42.1 0.0 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Bestrophin PF01062.21 OAG43104.1 - 1.3e-36 126.5 0.1 2.2e-36 125.8 0.1 1.2 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel T6SS_VasE PF05936.12 OAG43104.1 - 0.011 14.4 0.1 0.019 13.7 0.1 1.3 1 0 0 1 1 1 0 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE Glyco_transf_25 PF01755.17 OAG43105.1 - 1.4e-13 51.2 0.0 4.9e-12 46.1 0.0 2.5 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) Gly_transf_sug PF04488.15 OAG43106.1 - 4.8e-14 52.8 0.0 1e-13 51.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TPPK_C PF12555.8 OAG43106.1 - 0.22 11.6 1.8 0.43 10.7 1.8 1.4 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal Abhydrolase_1 PF00561.20 OAG43107.1 - 3.3e-20 72.8 0.1 3.2e-19 69.6 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAG43107.1 - 5.3e-16 58.6 0.0 4.5e-15 55.6 0.0 1.9 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OAG43107.1 - 1e-13 52.4 1.2 1.4e-13 51.9 1.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 OAG43107.1 - 3.8e-05 23.9 0.1 6.1e-05 23.2 0.1 1.4 1 0 0 1 1 1 1 Thioesterase domain FSH1 PF03959.13 OAG43107.1 - 0.055 13.1 0.0 1.4 8.6 0.0 2.1 2 0 0 2 2 2 0 Serine hydrolase (FSH1) DUF2048 PF09752.9 OAG43107.1 - 0.19 10.8 0.3 1.4 7.9 0.2 1.9 2 0 0 2 2 2 0 Abhydrolase domain containing 18 DUF3176 PF11374.8 OAG43108.1 - 3.2e-27 94.8 3.2 1.2e-26 93.0 1.9 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF3176) MS_channel PF00924.18 OAG43109.1 - 1.4e-14 54.2 0.5 3.3e-14 52.9 0.5 1.6 1 0 0 1 1 1 1 Mechanosensitive ion channel E1-E2_ATPase PF00122.20 OAG43109.1 - 0.71 9.4 3.5 2.3 7.7 0.2 2.4 2 0 0 2 2 2 0 E1-E2 ATPase 4HBT PF03061.22 OAG43110.1 - 9.2e-09 35.5 0.0 1.3e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_2 PF13279.6 OAG43110.1 - 1.6e-05 25.4 0.0 2e-05 25.0 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.17 OAG43110.1 - 0.00036 19.9 0.1 0.00051 19.4 0.1 1.1 1 0 0 1 1 1 1 Acyl-ACP thioesterase TPP1 PF10341.9 OAG43112.1 - 0.18 11.8 0.0 0.52 10.3 0.0 1.7 1 0 0 1 1 1 0 Shelterin complex subunit, TPP1/ACD adh_short_C2 PF13561.6 OAG43114.1 - 7.3e-35 120.6 3.7 1.4e-27 96.8 0.1 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG43114.1 - 5.4e-28 97.8 3.5 1.4e-17 63.8 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase DUF3295 PF11702.8 OAG43114.1 - 0.027 13.8 0.0 0.038 13.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) CMD PF02627.20 OAG43115.1 - 1.8e-18 66.4 0.2 2.9e-18 65.7 0.2 1.3 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family NAD_binding_8 PF13450.6 OAG43116.1 - 2.9e-11 43.4 0.0 8.1e-11 42.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.19 OAG43116.1 - 9.4e-09 34.2 0.0 7.3e-07 28.0 0.0 2.9 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 OAG43116.1 - 8e-07 28.6 0.0 0.0009 18.6 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG43116.1 - 2.8e-05 23.4 0.0 0.14 11.2 0.0 3.9 2 1 1 4 4 4 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 OAG43116.1 - 2.9e-05 23.5 0.0 0.0017 17.7 0.0 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAG43116.1 - 0.01 15.8 0.1 0.78 9.7 0.0 3.0 3 0 0 3 3 3 0 FAD-NAD(P)-binding Thi4 PF01946.17 OAG43116.1 - 0.15 11.3 0.0 11 5.1 0.0 2.9 3 0 0 3 3 3 0 Thi4 family DAO PF01266.24 OAG43116.1 - 0.17 11.4 0.0 3.4 7.1 0.0 2.4 1 1 0 1 1 1 0 FAD dependent oxidoreductase Fungal_trans PF04082.18 OAG43117.1 - 1.1e-06 27.9 0.0 1.4e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Lactamase_B PF00753.27 OAG43118.1 - 4.8e-07 30.0 0.2 8.4e-07 29.2 0.2 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OAG43118.1 - 0.0052 16.3 0.0 0.009 15.5 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain MFS_1 PF07690.16 OAG43119.1 - 1e-35 123.3 45.4 1.7e-34 119.3 29.0 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.18 OAG43120.1 - 1e-17 64.1 2.9 1.8e-17 63.3 2.9 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DNA_pol_viral_C PF00336.18 OAG43120.1 - 0.11 11.9 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase (viral) C-terminal domain DLIC PF05783.11 OAG43120.1 - 0.68 8.7 2.0 1 8.1 2.0 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) AMP-binding PF00501.28 OAG43121.1 - 9.7e-90 301.2 0.0 1.2e-89 300.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG43121.1 - 7.2e-14 52.5 0.0 1.4e-13 51.6 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Aldedh PF00171.22 OAG43122.1 - 2.1e-161 537.6 2.7 2.4e-161 537.4 2.7 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family ACOX PF01756.19 OAG43123.1 - 5.2e-40 136.9 0.1 3.6e-39 134.2 0.0 2.2 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 OAG43123.1 - 2e-26 93.0 0.0 3.7e-26 92.1 0.0 1.5 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 OAG43123.1 - 5.8e-09 36.0 0.0 1.6e-08 34.7 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 OAG43123.1 - 4e-07 30.3 0.6 8.9e-05 22.7 0.6 2.4 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DUF4743 PF15916.5 OAG43123.1 - 0.087 12.8 0.0 0.29 11.1 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4743) PIP5K PF01504.18 OAG43124.1 - 2e-36 125.6 0.3 1.4e-27 96.6 0.8 2.5 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 OAG43124.1 - 3.6e-25 88.6 0.0 6.3e-25 87.7 0.0 1.3 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.21 OAG43124.1 - 9.8e-14 51.2 8.9 2.6e-13 49.9 8.9 1.8 1 0 0 1 1 1 1 FYVE zinc finger C1_1 PF00130.22 OAG43124.1 - 0.013 15.4 5.7 0.038 13.9 5.7 1.8 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DZR PF12773.7 OAG43124.1 - 1.4 9.0 7.6 0.41 10.7 4.1 2.0 2 0 0 2 2 2 0 Double zinc ribbon FAD_binding_3 PF01494.19 OAG43126.1 - 1e-12 48.0 0.0 1.6e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain SE PF08491.10 OAG43126.1 - 0.00099 18.2 0.0 0.0019 17.3 0.0 1.4 1 0 0 1 1 1 1 Squalene epoxidase PS_Dcarbxylase PF02666.15 OAG43127.1 - 2.6e-55 187.1 0.0 4.1e-55 186.4 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.30 OAG43127.1 - 2.4e-37 127.4 0.0 3e-17 62.8 0.0 2.6 2 0 0 2 2 2 2 C2 domain YL1 PF05764.13 OAG43127.1 - 0.0064 16.6 2.2 0.0064 16.6 2.2 1.9 2 0 0 2 2 2 1 YL1 nuclear protein HhH-GPD PF00730.25 OAG43129.1 - 3.2e-07 30.8 0.0 5.1e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein DPBB_1 PF03330.18 OAG43130.1 - 4.2e-05 23.8 0.0 5.9e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 OAG43130.1 - 0.0079 16.0 0.1 0.011 15.5 0.1 1.2 1 0 0 1 1 1 1 Barwin family DUF373 PF04123.13 OAG43130.1 - 0.12 11.8 0.0 0.17 11.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) 4HB_MCP_1 PF12729.7 OAG43130.1 - 0.15 11.6 0.2 0.21 11.1 0.2 1.2 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction SUR7 PF06687.12 OAG43130.1 - 0.18 11.4 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 SUR7/PalI family Amidase PF01425.21 OAG43131.1 - 3.5e-71 240.5 0.6 4.3e-70 236.9 0.6 2.3 1 1 0 1 1 1 1 Amidase Fasciclin PF02469.22 OAG43132.1 - 1.5e-42 144.8 5.6 1.4e-25 90.0 1.0 2.2 2 0 0 2 2 2 2 Fasciclin domain HeLo PF14479.6 OAG43134.1 - 5.8e-08 32.8 0.0 9.9e-08 32.1 0.0 1.4 1 1 0 1 1 1 1 Prion-inhibition and propagation Acetyltransf_1 PF00583.25 OAG43136.1 - 1.7e-11 44.3 0.0 2.4e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OAG43136.1 - 7.2e-07 29.2 0.1 1e-06 28.7 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAG43136.1 - 1.6e-06 28.0 0.1 3.1e-06 27.1 0.1 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 OAG43136.1 - 3.6e-05 24.1 0.0 6.1e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 OAG43136.1 - 0.0088 16.1 0.2 0.014 15.4 0.2 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 OAG43136.1 - 0.085 12.3 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Putative acetyl-transferase adh_short_C2 PF13561.6 OAG43137.1 - 4.2e-41 141.0 0.0 1.1e-34 120.0 0.0 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG43137.1 - 7.5e-38 130.0 0.0 9.6e-38 129.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG43137.1 - 6.9e-12 45.6 0.0 1.1e-11 45.0 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG43137.1 - 0.0042 16.6 0.1 0.086 12.3 0.1 2.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Pkinase PF00069.25 OAG43138.1 - 1e-12 48.0 0.0 2e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain HEAT PF02985.22 OAG43138.1 - 7.6e-09 35.1 2.5 0.28 11.5 0.0 5.7 5 0 0 5 5 5 3 HEAT repeat Cnd1 PF12717.7 OAG43138.1 - 5.2e-06 26.6 0.1 0.00012 22.2 0.0 2.4 1 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Pkinase_Tyr PF07714.17 OAG43138.1 - 8.1e-06 25.3 0.0 1.4e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_2 PF13646.6 OAG43138.1 - 2.4e-05 24.7 0.5 0.0072 16.7 0.1 3.5 2 1 2 4 4 4 2 HEAT repeats HEAT_EZ PF13513.6 OAG43138.1 - 0.00059 20.3 0.4 1.4 9.5 0.0 3.6 2 1 1 3 3 3 2 HEAT-like repeat Kinase-like PF14531.6 OAG43138.1 - 0.11 11.8 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Kinase-like DUF1857 PF08982.11 OAG43140.1 - 4.6e-49 166.0 0.1 5.2e-49 165.9 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1857) Zn_clus PF00172.18 OAG43141.1 - 2e-05 24.6 10.8 2e-05 24.6 10.8 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 OAG43141.1 - 0.00018 20.4 0.4 0.00067 18.6 0.0 2.1 2 1 0 2 2 2 1 Fungal specific transcription factor domain SUR7 PF06687.12 OAG43142.1 - 1.4e-37 129.4 12.2 1.8e-37 129.1 12.2 1.1 1 0 0 1 1 1 1 SUR7/PalI family Zip PF02535.22 OAG43142.1 - 0.0098 15.1 0.0 0.018 14.3 0.0 1.4 1 0 0 1 1 1 1 ZIP Zinc transporter Phage_holin_3_6 PF07332.11 OAG43142.1 - 9.2 6.3 10.1 0.52 10.4 2.2 2.5 2 1 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III FXR_C3 PF16097.5 OAG43143.1 - 0.18 12.5 3.0 0.45 11.2 3.0 1.7 1 0 0 1 1 1 0 Fragile X-related 1 protein C-terminal region 3 HET PF06985.11 OAG43144.1 - 3.8e-30 105.2 0.0 9.8e-30 103.8 0.0 1.7 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) AA_permease PF00324.21 OAG43145.1 - 5.4e-100 335.3 44.9 6.1e-100 335.1 44.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAG43145.1 - 3.6e-29 101.8 48.8 4.5e-29 101.5 48.8 1.1 1 0 0 1 1 1 1 Amino acid permease Acetyltransf_1 PF00583.25 OAG43146.1 - 3.1e-05 24.2 0.0 4e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OAG43146.1 - 0.0011 18.9 0.0 0.0019 18.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAG43146.1 - 0.0079 16.1 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein TauD PF02668.16 OAG43147.1 - 4.8e-36 124.9 0.1 7.6e-36 124.3 0.1 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family ECH_1 PF00378.20 OAG43148.1 - 3.8e-36 124.7 0.0 5.8e-36 124.1 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAG43148.1 - 5.1e-18 65.7 0.0 6.3e-18 65.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Inhibitor_Mig-6 PF11555.8 OAG43148.1 - 0.064 13.4 0.0 0.61 10.2 0.0 2.3 2 0 0 2 2 2 0 EGFR receptor inhibitor Mig-6 MFS_1 PF07690.16 OAG43149.1 - 7.6e-13 48.1 26.4 7.6e-13 48.1 26.4 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 OAG43149.1 - 2.9e-10 40.1 4.9 6.7e-10 38.9 4.9 1.5 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 Sugar_tr PF00083.24 OAG43149.1 - 4.3e-06 25.8 7.9 4.3e-06 25.8 7.9 2.1 1 1 1 2 2 2 1 Sugar (and other) transporter Peptidase_M48_N PF16491.5 OAG43149.1 - 2 8.3 10.2 6.8 6.5 0.0 3.6 3 0 0 3 3 3 0 CAAX prenyl protease N-terminal, five membrane helices Fructosamin_kin PF03881.14 OAG43150.1 - 3.1e-41 141.5 0.1 3.7e-41 141.2 0.1 1.1 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 OAG43150.1 - 0.00064 19.7 0.0 0.00084 19.3 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family ANAPC4_WD40 PF12894.7 OAG43151.1 - 4e-11 43.1 0.0 0.00031 21.0 0.1 4.5 3 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PGAP1 PF07819.13 OAG43151.1 - 3e-07 30.4 0.0 7.4e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 PGAP1-like protein NACHT PF05729.12 OAG43151.1 - 4.6e-05 23.4 0.0 0.0001 22.3 0.0 1.6 1 0 0 1 1 1 1 NACHT domain DUF676 PF05057.14 OAG43151.1 - 9e-05 22.1 0.0 0.00087 18.9 0.0 2.3 3 0 0 3 3 3 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 OAG43151.1 - 0.0002 22.0 0.0 0.00075 20.2 0.0 2.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family AAA_16 PF13191.6 OAG43151.1 - 0.0017 18.7 0.0 0.0065 16.9 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain Abhydrolase_1 PF00561.20 OAG43151.1 - 0.0048 16.6 0.3 0.016 14.8 0.3 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Coatomer_WDAD PF04053.14 OAG43151.1 - 0.0088 15.1 0.0 2.8 6.9 0.0 2.2 1 1 1 2 2 2 2 Coatomer WD associated region Hydrolase_4 PF12146.8 OAG43151.1 - 0.024 13.9 0.0 0.064 12.5 0.0 1.7 1 0 0 1 1 1 0 Serine aminopeptidase, S33 RNA_helicase PF00910.22 OAG43151.1 - 0.028 14.8 0.1 0.11 12.9 0.0 2.1 2 0 0 2 2 2 0 RNA helicase AAA_22 PF13401.6 OAG43151.1 - 0.031 14.5 0.1 2.3 8.5 0.0 3.1 3 0 0 3 3 3 0 AAA domain WD40 PF00400.32 OAG43151.1 - 0.033 15.1 1.9 60 4.7 0.1 5.5 6 0 0 6 6 4 0 WD domain, G-beta repeat APS_kinase PF01583.20 OAG43151.1 - 0.077 12.9 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_14 PF13173.6 OAG43151.1 - 0.09 12.8 0.4 7.3 6.6 0.1 3.0 2 1 0 2 2 2 0 AAA domain Cu-oxidase_3 PF07732.15 OAG43152.1 - 4.3e-36 123.5 1.0 4.3e-36 123.5 1.0 2.1 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 OAG43152.1 - 9.4e-30 103.1 0.3 9.4e-30 103.1 0.3 3.2 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.22 OAG43152.1 - 5.5e-25 88.3 0.1 1.3e-24 87.1 0.1 1.6 1 0 0 1 1 1 1 Multicopper oxidase Pmp3 PF01679.17 OAG43153.1 - 5.4e-20 71.3 9.4 7.1e-20 71.0 9.4 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator PEX11 PF05648.14 OAG43154.1 - 6.6e-08 32.3 0.5 3.7e-07 29.9 0.5 2.2 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Fungal_trans PF04082.18 OAG43155.1 - 4.6e-17 61.9 0.8 7.1e-17 61.3 0.2 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain NmrA PF05368.13 OAG43156.1 - 5.8e-14 52.2 0.0 1.1e-13 51.3 0.0 1.4 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG43156.1 - 8.5e-11 42.1 0.0 1.4e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAG43156.1 - 5.6e-05 22.7 0.0 0.00017 21.1 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAG43156.1 - 0.0035 16.8 0.0 0.0057 16.1 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Semialdhyde_dh PF01118.24 OAG43156.1 - 0.011 16.2 0.0 0.023 15.1 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.17 OAG43156.1 - 0.081 12.0 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Amidohydro_1 PF01979.20 OAG43157.1 - 3.7e-29 102.1 0.3 9.4e-28 97.5 0.3 2.0 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 OAG43157.1 - 3.7e-16 59.7 0.4 1.3e-07 31.4 0.1 2.3 2 0 0 2 2 2 2 Amidohydrolase family PIR PF00399.19 OAG43158.1 - 6.9e-08 31.8 27.5 1.9e-06 27.3 5.0 3.1 3 0 0 3 3 3 2 Yeast PIR protein repeat SPX PF03105.19 OAG43158.1 - 1.2 8.9 4.3 1.4 8.7 4.3 1.2 1 0 0 1 1 1 0 SPX domain MRI PF15325.6 OAG43158.1 - 2.4 9.3 8.6 3.2 8.9 0.1 2.6 2 0 0 2 2 2 0 Modulator of retrovirus infection LRR_4 PF12799.7 OAG43159.1 - 8.9e-30 102.3 38.4 4e-06 27.1 0.3 8.9 7 2 2 9 9 9 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OAG43159.1 - 5.2e-23 80.6 33.0 5.9e-07 29.1 3.1 7.3 3 2 5 8 8 8 8 Leucine rich repeat LRR_9 PF14580.6 OAG43159.1 - 7.2e-09 35.4 11.6 0.27 10.7 0.1 4.9 2 1 3 5 5 5 4 Leucine-rich repeat LRR_6 PF13516.6 OAG43159.1 - 4.8e-05 23.1 25.8 1.3 9.3 0.0 9.9 11 1 1 12 12 12 3 Leucine Rich repeat LRR_1 PF00560.33 OAG43159.1 - 0.00068 19.8 22.5 9.3 7.2 0.1 9.8 9 2 0 9 9 9 2 Leucine Rich Repeat Mito_carr PF00153.27 OAG43160.1 - 3.2e-46 155.2 1.6 1.8e-20 72.6 0.1 3.7 3 0 0 3 3 3 3 Mitochondrial carrier protein GFA PF04828.14 OAG43160.1 - 0.043 14.2 0.3 0.69 10.3 0.3 2.4 1 1 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme Serine_protease PF18405.1 OAG43160.1 - 0.11 11.6 0.4 1.8 7.6 0.1 2.4 2 1 0 2 2 2 0 Gammaproteobacterial serine protease DUF3337 PF11816.8 OAG43161.1 - 1.6e-56 190.9 0.0 4.5e-56 189.4 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3337) WD40 PF00400.32 OAG43161.1 - 3e-18 65.8 21.2 4e-05 24.3 0.4 6.6 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG43161.1 - 1.8e-05 24.9 0.7 0.0099 16.2 0.1 3.6 2 2 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OAG43161.1 - 0.05 12.3 0.1 0.12 10.9 0.1 1.6 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 OAG43161.1 - 0.1 11.5 0.3 0.5 9.3 0.0 1.9 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_3 PF13570.6 OAG43161.1 - 0.29 11.7 4.6 1 9.9 0.2 3.5 4 0 0 4 4 4 0 PQQ-like domain Pkinase PF00069.25 OAG43162.1 - 6.4e-49 166.7 0.0 1.3e-48 165.6 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG43162.1 - 3.2e-23 82.3 0.0 6.6e-23 81.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAG43162.1 - 0.0071 15.7 0.0 0.024 13.9 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 OAG43162.1 - 0.011 15.7 0.0 0.022 14.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OAG43162.1 - 0.024 13.6 0.0 0.044 12.7 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain PIP49_C PF12260.8 OAG43162.1 - 0.2 11.3 0.0 0.35 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 DUF2781 PF10914.8 OAG43162.1 - 0.22 12.0 0.0 0.33 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2781) Ribosomal_L11 PF00298.19 OAG43163.1 - 1e-28 99.6 0.1 1.7e-28 98.9 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.14 OAG43163.1 - 1.7e-25 88.6 0.3 2.6e-25 88.0 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Svf1 PF08622.10 OAG43164.1 - 5.2e-53 179.4 0.1 7.2e-53 179.0 0.1 1.2 1 0 0 1 1 1 1 Svf1-like N-terminal lipocalin domain Svf1_C PF17187.4 OAG43164.1 - 1.2e-46 158.5 0.0 2.4e-46 157.6 0.0 1.5 1 0 0 1 1 1 1 Svf1-like C-terminal lipocalin-like domain ADH_zinc_N PF00107.26 OAG43165.1 - 5.4e-26 91.1 0.1 7.7e-26 90.6 0.1 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAG43165.1 - 1.4e-19 71.4 0.0 2.2e-19 70.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG43165.1 - 1.4e-08 34.5 0.0 8.6e-07 28.8 0.0 2.5 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 OAG43165.1 - 1.3e-05 25.1 0.0 2.4e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ATP-synt_C PF00137.21 OAG43167.1 - 1.2e-23 83.2 36.0 3.3e-15 56.2 10.8 2.7 3 0 0 3 3 3 2 ATP synthase subunit C SLATT_5 PF18160.1 OAG43167.1 - 0.17 11.2 0.0 0.17 11.2 0.0 1.7 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 DDHD PF02862.17 OAG43168.1 - 4.2e-23 82.7 2.2 1.2e-12 48.5 0.0 3.5 3 1 0 4 4 4 2 DDHD domain MoCF_biosynth PF00994.24 OAG43169.1 - 2.2e-46 157.1 0.1 6.7e-23 80.9 0.0 2.3 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.17 OAG43169.1 - 3.5e-37 127.6 4.0 5.3e-37 127.0 4.0 1.3 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.15 OAG43169.1 - 8.7e-16 57.9 0.1 2.3e-15 56.5 0.1 1.8 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) SelP_N PF04592.14 OAG43169.1 - 6.4 6.1 12.8 10 5.4 12.8 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Tannase PF07519.11 OAG43170.1 - 4.6e-93 312.7 0.0 7.9e-93 311.9 0.0 1.3 1 0 0 1 1 1 1 Tannase and feruloyl esterase Hydrolase_4 PF12146.8 OAG43170.1 - 0.00023 20.5 0.0 0.0036 16.6 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 OAG43170.1 - 0.0028 17.1 0.3 0.87 9.0 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family RNA_pol PF00940.19 OAG43171.1 - 1.2e-180 600.8 0.0 1.8e-180 600.2 0.0 1.3 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 OAG43171.1 - 4e-86 289.5 0.1 8.9e-86 288.3 0.1 1.6 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal GFO_IDH_MocA PF01408.22 OAG43172.1 - 4.5e-18 66.2 0.0 1.1e-17 65.0 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 OAG43172.1 - 0.0012 19.5 0.1 0.04 14.6 0.0 2.3 2 0 0 2 2 2 1 Homoserine dehydrogenase, NAD binding domain IlvC PF01450.19 OAG43172.1 - 0.0083 16.4 0.1 0.015 15.6 0.1 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain Sin_N PF04801.13 OAG43173.1 - 2e-26 93.2 0.1 4.6e-26 92.0 0.0 1.5 1 1 0 1 1 1 1 Sin-like protein conserved region AT_hook PF02178.19 OAG43173.1 - 0.26 11.3 8.0 0.91 9.6 8.0 2.0 1 0 0 1 1 1 0 AT hook motif Pkinase_Tyr PF07714.17 OAG43174.1 - 6.1e-15 55.2 0.0 6.5e-13 48.6 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OAG43174.1 - 6.8e-15 55.1 0.1 2.4e-14 53.3 0.1 1.9 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.23 OAG43174.1 - 0.05 13.5 0.4 0.12 12.2 0.4 1.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family NIR_SIR PF01077.22 OAG43175.1 - 2.2e-49 167.0 0.0 1.7e-44 151.1 0.0 2.4 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 OAG43175.1 - 7.4e-31 105.8 0.0 2e-14 53.2 0.0 2.6 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.25 OAG43175.1 - 4.5e-29 101.5 0.0 9.9e-29 100.4 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin POR_N PF01855.19 OAG43175.1 - 2.3e-06 27.5 0.5 5.6e-06 26.3 0.1 1.8 2 0 0 2 2 2 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Methyltransf_11 PF08241.12 OAG43176.1 - 2.2e-19 69.9 0.2 7.4e-18 65.0 0.2 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAG43176.1 - 1.6e-17 63.8 0.0 2.3e-17 63.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 OAG43176.1 - 5.9e-17 61.9 0.0 9e-16 58.0 0.0 2.0 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 OAG43176.1 - 5.9e-17 62.2 0.2 3.8e-07 30.7 0.1 2.4 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 OAG43176.1 - 6e-14 52.6 0.0 9.9e-13 48.7 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG43176.1 - 1e-13 51.3 0.0 9.1e-07 28.8 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Ubie_methyltran PF01209.18 OAG43176.1 - 6.6e-07 28.9 0.0 5.5e-05 22.6 0.0 2.2 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 OAG43176.1 - 0.00023 20.8 0.0 0.012 15.2 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase small domain MetW PF07021.12 OAG43176.1 - 0.00025 20.7 0.0 0.0052 16.4 0.0 2.2 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW Methyltransf_PK PF05891.12 OAG43176.1 - 0.0011 18.5 0.0 0.06 12.8 0.0 2.1 2 0 0 2 2 2 1 AdoMet dependent proline di-methyltransferase DOT1 PF08123.13 OAG43176.1 - 0.0028 17.2 0.0 0.0056 16.2 0.0 1.4 1 0 0 1 1 1 1 Histone methylation protein DOT1 RrnaAD PF00398.20 OAG43176.1 - 0.015 14.4 0.0 0.021 13.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_32 PF13679.6 OAG43176.1 - 0.027 14.5 0.0 0.039 13.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain ADH_zinc_N PF00107.26 OAG43176.1 - 0.036 14.0 0.0 0.97 9.4 0.0 2.4 2 0 0 2 2 2 0 Zinc-binding dehydrogenase PCMT PF01135.19 OAG43176.1 - 0.062 13.0 0.0 0.09 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.17 OAG43176.1 - 0.13 11.7 0.0 0.77 9.2 0.0 2.2 1 1 0 1 1 1 0 Putative methyltransferase Caleosin PF05042.13 OAG43177.1 - 2.2e-65 219.7 0.4 3.1e-65 219.2 0.4 1.2 1 0 0 1 1 1 1 Caleosin related protein EF-hand_6 PF13405.6 OAG43177.1 - 0.029 14.3 0.1 8.1 6.7 0.0 2.7 2 0 0 2 2 2 0 EF-hand domain EF-hand_8 PF13833.6 OAG43177.1 - 0.05 13.5 0.1 1.1 9.2 0.1 2.3 2 0 0 2 2 2 0 EF-hand domain pair p450 PF00067.22 OAG43178.1 - 3.7e-46 157.8 0.0 4.6e-46 157.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Reticulon PF02453.17 OAG43178.1 - 0.026 14.5 0.5 0.045 13.7 0.0 1.6 2 0 0 2 2 2 0 Reticulon Methyltransf_23 PF13489.6 OAG43179.1 - 3.5e-19 69.2 0.0 5.4e-19 68.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG43179.1 - 3.1e-06 27.1 0.0 0.00011 22.0 0.0 2.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG43179.1 - 4.6e-06 27.3 0.0 9.4e-05 23.0 0.0 2.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG43179.1 - 0.0016 19.1 0.0 0.019 15.6 0.0 2.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG43179.1 - 0.002 18.8 0.0 0.024 15.4 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 OAG43179.1 - 0.019 15.1 0.0 0.035 14.2 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Nitroreductase PF00881.24 OAG43180.1 - 2.7e-10 40.6 0.1 5e-10 39.7 0.1 1.5 1 1 0 1 1 1 1 Nitroreductase family FAD_binding_3 PF01494.19 OAG43182.1 - 1.2e-17 64.2 0.0 1.9e-17 63.5 0.0 1.3 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 OAG43182.1 - 4.4e-08 32.7 0.0 1.4e-07 31.0 0.1 1.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAG43182.1 - 3.9e-07 30.0 1.4 0.00024 20.8 1.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAG43182.1 - 6.3e-07 29.5 0.6 1.7e-06 28.2 0.6 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 OAG43182.1 - 3.4e-05 23.1 1.4 6.7e-05 22.1 1.4 1.5 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 OAG43182.1 - 4.4e-05 22.4 0.7 0.002 16.9 0.5 2.1 2 0 0 2 2 2 1 HI0933-like protein Trp_halogenase PF04820.14 OAG43182.1 - 0.00013 20.9 1.3 0.11 11.3 0.5 3.0 3 0 0 3 3 3 2 Tryptophan halogenase Amino_oxidase PF01593.24 OAG43182.1 - 0.00029 20.3 0.5 0.018 14.4 0.1 2.4 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase GIDA PF01134.22 OAG43182.1 - 0.00035 19.8 2.2 0.0011 18.1 1.2 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 OAG43182.1 - 0.0088 15.4 0.3 0.014 14.8 0.3 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase SE PF08491.10 OAG43182.1 - 0.011 14.9 0.0 0.021 13.9 0.0 1.4 2 0 0 2 2 2 0 Squalene epoxidase 3HCDH_N PF02737.18 OAG43182.1 - 0.013 15.3 0.3 0.024 14.5 0.3 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Rossmann-like PF10727.9 OAG43182.1 - 0.016 15.1 0.3 0.036 13.9 0.3 1.5 1 0 0 1 1 1 0 Rossmann-like domain Pyr_redox PF00070.27 OAG43182.1 - 0.028 15.0 0.3 0.074 13.6 0.3 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 OAG43182.1 - 0.031 13.6 0.2 0.059 12.6 0.2 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 OAG43182.1 - 0.079 12.2 0.8 0.13 11.5 0.3 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 OAG43182.1 - 0.14 11.8 0.4 0.23 11.1 0.4 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA ABC2_membrane PF01061.24 OAG43183.1 - 3.1e-77 258.7 74.9 8e-42 143.0 27.7 3.6 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 OAG43183.1 - 2.2e-33 115.7 0.1 3.6e-16 59.9 0.0 3.3 3 1 0 3 3 3 2 ABC transporter PDR_CDR PF06422.12 OAG43183.1 - 1.1e-28 98.9 3.9 1.4e-27 95.4 0.4 4.5 5 0 0 5 5 4 2 CDR ABC transporter ABC_trans_N PF14510.6 OAG43183.1 - 1.1e-13 51.6 1.3 4.3e-13 49.7 0.1 2.4 2 0 0 2 2 2 1 ABC-transporter N-terminal AAA_33 PF13671.6 OAG43183.1 - 9.7e-06 25.8 0.1 0.037 14.2 0.1 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 OAG43183.1 - 1.4e-05 25.6 0.1 0.0035 17.8 0.1 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 OAG43183.1 - 2.1e-05 24.2 0.1 0.00015 21.4 0.1 2.1 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 OAG43183.1 - 3.1e-05 23.9 0.1 0.0014 18.5 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase NACHT PF05729.12 OAG43183.1 - 4.2e-05 23.5 0.1 0.053 13.4 0.0 2.7 2 0 0 2 2 2 2 NACHT domain AAA_29 PF13555.6 OAG43183.1 - 8.1e-05 22.3 3.3 0.00082 19.1 0.3 2.9 3 0 0 3 3 2 1 P-loop containing region of AAA domain ABC2_membrane_3 PF12698.7 OAG43183.1 - 0.0005 19.3 18.5 0.0005 19.3 18.5 3.4 2 2 1 3 3 3 1 ABC-2 family transporter protein cobW PF02492.19 OAG43183.1 - 0.00062 19.4 0.2 0.013 15.1 0.0 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_21 PF13304.6 OAG43183.1 - 0.0015 18.4 0.1 0.37 10.5 0.0 3.0 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OAG43183.1 - 0.0017 17.8 0.2 0.73 9.2 0.0 2.9 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_18 PF13238.6 OAG43183.1 - 0.0026 18.3 0.1 0.018 15.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 OAG43183.1 - 0.0052 16.9 0.0 2.1 8.4 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 OAG43183.1 - 0.0054 17.0 1.0 0.086 13.1 0.1 2.7 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.6 OAG43183.1 - 0.0057 16.9 0.1 0.014 15.6 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 OAG43183.1 - 0.012 16.0 0.3 0.66 10.4 0.1 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 OAG43183.1 - 0.019 15.4 0.1 0.91 9.9 0.0 3.1 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 OAG43183.1 - 0.02 15.3 0.0 8 6.9 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_23 PF13476.6 OAG43183.1 - 0.026 15.0 0.0 0.026 15.0 0.0 2.6 3 0 0 3 3 2 0 AAA domain AAA_30 PF13604.6 OAG43183.1 - 0.04 13.6 0.1 0.96 9.1 0.1 2.3 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 OAG43183.1 - 0.051 12.6 0.2 10 5.1 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein NTPase_1 PF03266.15 OAG43183.1 - 0.067 13.1 0.5 16 5.3 0.2 3.0 3 0 0 3 3 3 0 NTPase OCD_Mu_crystall PF02423.15 OAG43183.1 - 0.093 11.6 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family Pax2_C PF12403.8 OAG43183.1 - 0.13 12.4 1.7 0.22 11.6 0.1 2.2 2 0 0 2 2 2 0 Paired-box protein 2 C terminal TsaE PF02367.17 OAG43183.1 - 0.22 11.6 0.5 1 9.4 0.2 2.1 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE CLP1_P PF16575.5 OAG43184.1 - 9.3e-33 113.6 0.0 1.9e-27 96.3 0.0 2.5 1 1 1 2 2 2 2 mRNA cleavage and polyadenylation factor CLP1 P-loop CLP1_N PF16573.5 OAG43184.1 - 2.1e-32 111.2 0.1 4.1e-32 110.3 0.1 1.5 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor Clp1 PF06807.14 OAG43184.1 - 6.7e-25 87.8 0.0 1.2e-24 86.9 0.0 1.5 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 ATP_bind_1 PF03029.17 OAG43184.1 - 0.0039 17.0 0.0 0.043 13.6 0.0 2.1 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 OAG43184.1 - 0.029 14.5 0.0 0.15 12.2 0.0 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.27 OAG43184.1 - 0.052 14.1 0.0 0.11 13.0 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 OAG43184.1 - 0.086 12.6 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_35 PF14516.6 OAG43184.1 - 0.13 11.0 0.0 0.2 10.4 0.0 1.1 1 0 0 1 1 1 0 AAA-like domain SRPRB PF09439.10 OAG43184.1 - 0.16 11.4 0.0 0.3 10.5 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Sigma54_activat PF00158.26 OAG43184.1 - 0.16 11.6 0.0 0.37 10.5 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain IPK PF03770.16 OAG43185.1 - 8.9e-58 195.4 0.0 1.4e-57 194.7 0.0 1.3 1 0 0 1 1 1 1 Inositol polyphosphate kinase CENP-B_dimeris PF09026.10 OAG43185.1 - 0.0056 17.0 7.2 0.012 16.0 7.2 1.5 1 0 0 1 1 1 1 Centromere protein B dimerisation domain RXT2_N PF08595.11 OAG43185.1 - 0.12 12.4 3.3 0.2 11.7 3.3 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF2457 PF10446.9 OAG43185.1 - 0.16 11.1 9.8 0.24 10.5 9.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DNA_pol_phi PF04931.13 OAG43185.1 - 0.46 8.5 13.3 0.65 8.0 13.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF4611 PF15387.6 OAG43185.1 - 1.2 9.4 9.0 4 7.7 9.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) NOA36 PF06524.12 OAG43185.1 - 1.5 8.1 10.6 2.3 7.5 10.6 1.2 1 0 0 1 1 1 0 NOA36 protein PBP1_TM PF14812.6 OAG43185.1 - 5.5 7.4 11.8 2.7 8.4 9.0 1.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Arb1 PF09692.10 OAG43186.1 - 3.9e-118 395.1 0.0 4.8e-118 394.8 0.0 1.1 1 0 0 1 1 1 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 Fmp27 PF10344.9 OAG43187.1 - 8.6e-186 619.7 0.0 1.8e-185 618.6 0.0 1.6 2 0 0 2 2 2 1 Mitochondrial protein from FMP27 Fmp27_WPPW PF10359.9 OAG43187.1 - 3.1e-177 590.3 0.6 3.1e-177 590.3 0.6 2.6 4 0 0 4 4 4 1 RNA pol II promoter Fmp27 protein domain Apt1 PF10351.9 OAG43187.1 - 6.2e-175 582.6 1.3 6.2e-175 582.6 1.3 3.3 3 0 0 3 3 3 1 Golgi-body localisation protein domain DUF2405 PF10293.9 OAG43187.1 - 1.1e-56 191.1 0.3 3.2e-56 189.5 0.3 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_GFWDK PF10347.9 OAG43187.1 - 1e-52 178.4 0.1 3.2e-52 176.8 0.0 2.0 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain Fmp27_SW PF10305.9 OAG43187.1 - 1.1e-33 116.0 1.2 6.5e-33 113.5 0.0 3.1 3 0 0 3 3 3 1 RNA pol II promoter Fmp27 protein domain DUF5082 PF16888.5 OAG43188.1 - 0.059 13.6 0.2 0.1 12.9 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) Osmo_CC PF08946.10 OAG43188.1 - 0.37 11.1 1.2 0.54 10.6 1.2 1.2 1 0 0 1 1 1 0 Osmosensory transporter coiled coil Bacteriocin_IIc PF10439.9 OAG43188.1 - 1.4 9.1 11.6 4.7 7.4 6.3 2.4 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide RRM_1 PF00076.22 OAG43189.1 - 5e-11 42.3 0.1 1.1e-10 41.2 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PIEZO PF15917.5 OAG43189.1 - 7.2 6.0 12.2 10 5.5 12.2 1.2 1 0 0 1 1 1 0 Piezo B-block_TFIIIC PF04182.12 OAG43190.1 - 1.7e-18 66.5 0.3 3e-16 59.3 0.0 3.5 4 0 0 4 4 4 1 B-block binding subunit of TFIIIC MarR_2 PF12802.7 OAG43190.1 - 0.00021 21.1 1.4 0.28 11.1 0.0 4.3 4 0 0 4 4 4 2 MarR family MMS1_N PF10433.9 OAG43191.1 - 1.6e-125 419.5 0.0 3.9e-125 418.3 0.0 1.6 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 OAG43191.1 - 5.8e-57 193.4 0.0 6.3e-56 190.0 0.0 2.5 3 0 0 3 3 3 1 CPSF A subunit region DNA_ligase_ZBD PF03119.16 OAG43192.1 - 0.13 12.3 2.9 0.3 11.2 2.9 1.7 1 0 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain adh_short_C2 PF13561.6 OAG43193.1 - 6.2e-38 130.7 0.8 4.5e-22 78.7 0.4 4.1 3 1 0 3 3 3 3 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG43193.1 - 3.6e-37 127.7 1.3 3.5e-27 95.1 0.7 3.1 2 1 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 OAG43193.1 - 2.8e-07 30.6 0.1 5.6e-07 29.6 0.1 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG43193.1 - 0.13 11.7 0.0 1.8 8.0 0.0 2.3 3 0 0 3 3 3 0 NAD dependent epimerase/dehydratase family CMD PF02627.20 OAG43194.1 - 1.6e-16 60.1 0.1 2.5e-16 59.5 0.1 1.2 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family MFS_1 PF07690.16 OAG43195.1 - 9.8e-30 103.7 44.5 1.3e-25 90.1 29.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily RICTOR_V PF14668.6 OAG43195.1 - 0.017 15.4 0.9 0.25 11.6 0.2 2.4 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, domain 5 Kinocilin PF15033.6 OAG43195.1 - 4.6 6.9 5.1 1.7 8.3 1.9 1.9 2 0 0 2 2 2 0 Kinocilin protein FMO-like PF00743.19 OAG43196.1 - 3.9e-16 58.6 0.0 1.3e-11 43.7 0.0 2.3 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OAG43196.1 - 4.4e-10 39.6 0.0 1.1e-09 38.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAG43196.1 - 1.2e-09 37.9 0.0 2.7e-07 30.1 0.0 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG43196.1 - 3.3e-09 36.4 0.0 1.7e-07 30.7 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 OAG43196.1 - 1.1e-07 31.4 0.0 5e-06 26.0 0.0 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAG43196.1 - 0.00017 21.6 1.0 0.39 10.7 0.0 3.9 3 1 1 4 4 4 1 FAD-NAD(P)-binding Thi4 PF01946.17 OAG43196.1 - 0.00033 20.0 0.0 0.8 8.9 0.0 2.8 3 0 0 3 3 3 2 Thi4 family Amino_oxidase PF01593.24 OAG43196.1 - 0.0015 17.9 0.0 2.6 7.2 0.0 3.2 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 OAG43196.1 - 0.0059 17.1 0.0 1.6 9.4 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GBP_PSP PF02425.15 OAG43196.1 - 0.062 13.0 3.6 0.3 10.8 0.1 3.1 3 0 0 3 3 3 0 Paralytic/GBP/PSP peptide Shikimate_DH PF01488.20 OAG43196.1 - 0.22 11.6 0.0 0.94 9.5 0.0 2.0 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Fungal_trans PF04082.18 OAG43197.1 - 2.5e-26 92.3 0.0 3.9e-26 91.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG43197.1 - 1.7e-07 31.2 6.5 3.6e-07 30.2 6.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Trypan_PARP PF05887.11 OAG43197.1 - 0.055 13.4 9.9 0.021 14.8 6.0 2.2 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) XLF PF09302.11 OAG43198.1 - 0.043 14.0 1.2 0.08 13.1 1.2 1.4 1 0 0 1 1 1 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component PKcGMP_CC PF16808.5 OAG43198.1 - 0.044 13.6 4.5 0.11 12.4 4.5 1.6 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase IFP_35_N PF07334.13 OAG43198.1 - 0.063 13.4 1.5 0.21 11.7 1.5 1.8 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus DUF641 PF04859.12 OAG43198.1 - 0.07 13.5 1.6 0.081 13.3 0.3 1.7 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) ADIP PF11559.8 OAG43198.1 - 1.8 8.7 5.8 13 5.8 3.6 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding FlaC_arch PF05377.11 OAG43198.1 - 5 7.6 5.6 3.9 7.9 1.9 2.5 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Lactamase_B PF00753.27 OAG43199.1 - 3.9e-08 33.6 0.1 8e-08 32.5 0.1 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OAG43199.1 - 0.011 15.2 0.1 0.023 14.2 0.1 1.6 1 1 0 1 1 1 0 Beta-lactamase superfamily domain ADH_zinc_N PF00107.26 OAG43200.1 - 1.7e-24 86.3 0.8 2.7e-24 85.6 0.8 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAG43200.1 - 6.8e-10 40.1 0.0 1.4e-09 39.1 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG43200.1 - 3.4e-07 30.1 0.2 3.4e-07 30.1 0.2 2.0 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain DAGK_cat PF00781.24 OAG43200.1 - 0.01 15.4 0.4 0.018 14.7 0.4 1.3 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain PapG_C PF03628.13 OAG43200.1 - 0.039 13.8 0.1 0.092 12.6 0.1 1.6 1 0 0 1 1 1 0 PapG chaperone-binding domain Ctr PF04145.15 OAG43202.1 - 1.8e-42 145.4 0.2 2.2e-42 145.1 0.2 1.1 1 0 0 1 1 1 1 Ctr copper transporter family Ferric_reduct PF01794.19 OAG43203.1 - 2.6e-20 72.8 10.2 2.6e-20 72.8 10.2 2.6 3 0 0 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 OAG43203.1 - 0.00062 19.9 0.9 2.1 8.4 0.3 3.2 2 1 1 3 3 3 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 OAG43203.1 - 0.003 17.6 0.0 0.011 15.9 0.0 1.9 2 0 0 2 2 2 1 FAD-binding domain TP2 PF01254.18 OAG43204.1 - 2.3 8.8 16.4 0.21 12.2 11.1 2.0 2 0 0 2 2 2 0 Nuclear transition protein 2 WD40 PF00400.32 OAG43207.1 - 2e-29 101.2 10.6 6.9e-07 29.9 0.8 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.8 OAG43207.1 - 3.6e-08 32.5 4.5 0.052 12.2 0.3 5.1 4 1 1 5 5 5 3 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 OAG43207.1 - 4e-07 30.3 0.0 0.14 12.5 0.0 4.7 3 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain EzrA PF06160.12 OAG43207.1 - 0.016 13.4 3.6 0.023 12.9 3.6 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA APG6_N PF17675.1 OAG43207.1 - 0.021 15.4 5.1 0.04 14.4 5.1 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region BBS2_Mid PF14783.6 OAG43207.1 - 0.041 13.9 0.0 0.74 9.9 0.0 3.1 4 1 0 4 4 3 0 Ciliary BBSome complex subunit 2, middle region DUF4482 PF14818.6 OAG43207.1 - 0.045 14.6 1.7 0.12 13.2 1.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4482) AAA_23 PF13476.6 OAG43207.1 - 0.19 12.2 1.2 0.3 11.6 1.2 1.2 1 0 0 1 1 1 0 AAA domain FAM76 PF16046.5 OAG43207.1 - 0.91 8.8 2.3 1.5 8.1 2.3 1.3 1 0 0 1 1 1 0 FAM76 protein Uds1 PF15456.6 OAG43207.1 - 2.7 8.1 9.0 0.14 12.3 2.5 2.2 2 1 0 2 2 2 0 Up-regulated During Septation FapA PF03961.13 OAG43207.1 - 3.5 6.1 5.4 5.4 5.5 5.4 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF1664 PF07889.12 OAG43207.1 - 3.7 7.6 5.5 9.2 6.3 4.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) TUG-UBL1 PF11470.8 OAG43208.1 - 0.13 12.5 0.0 0.5 10.6 0.0 1.9 2 0 0 2 2 2 0 TUG ubiquitin-like domain BCIP PF13862.6 OAG43209.1 - 1.8e-69 233.7 0.0 2.2e-69 233.3 0.0 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein GMP_synt_C PF00958.22 OAG43210.1 - 6.1e-41 138.4 0.0 1.4e-40 137.2 0.0 1.7 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.28 OAG43210.1 - 3.7e-40 137.7 0.0 6.2e-40 137.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.17 OAG43210.1 - 8.8e-11 41.4 0.1 1.9e-06 27.2 0.0 2.3 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 OAG43210.1 - 6e-07 29.4 0.0 1.3e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 QueC PF06508.13 OAG43210.1 - 0.0013 18.3 0.0 0.0042 16.6 0.0 1.7 1 1 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 OAG43210.1 - 0.0054 15.6 0.1 0.014 14.2 0.0 1.7 2 0 0 2 2 2 1 tRNA methyl transferase ThiI PF02568.14 OAG43210.1 - 0.0095 15.5 0.0 0.027 14.0 0.0 1.7 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) PAPS_reduct PF01507.19 OAG43210.1 - 0.029 14.4 0.0 0.047 13.7 0.0 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family Arginosuc_synth PF00764.19 OAG43210.1 - 0.14 11.4 0.1 0.23 10.7 0.1 1.2 1 0 0 1 1 1 0 Arginosuccinate synthase ATP_bind_3 PF01171.20 OAG43210.1 - 0.17 11.6 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 PP-loop family TauD PF02668.16 OAG43211.1 - 1.4e-54 185.7 0.1 2e-54 185.2 0.1 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF2183 PF09949.9 OAG43213.1 - 9.6e-34 115.7 0.0 7.7e-33 112.8 0.0 2.5 2 1 1 3 3 3 1 Uncharacterized conserved protein (DUF2183) CarboxypepD_reg PF13620.6 OAG43213.1 - 0.0015 18.8 0.3 0.018 15.3 0.1 2.7 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain LNS2 PF08235.13 OAG43213.1 - 0.016 14.7 0.0 0.027 13.9 0.0 1.2 1 0 0 1 1 1 0 LNS2 (Lipin/Ned1/Smp2) DUF4058 PF13267.6 OAG43213.1 - 0.063 12.7 0.1 0.11 11.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4058) Cut12 PF11500.8 OAG43213.1 - 7 6.6 7.8 0.32 11.0 1.4 2.0 2 0 0 2 2 2 0 Spindle pole body formation-associated protein HD_5 PF13487.6 OAG43215.1 - 0.05 13.9 0.0 0.2 12.0 0.0 2.0 2 0 0 2 2 2 0 HD domain Rab_bind PF16704.5 OAG43215.1 - 0.15 12.1 0.0 0.73 9.9 0.1 2.1 2 0 0 2 2 2 0 Rab binding domain WD40 PF00400.32 OAG43216.1 - 0.00035 21.3 5.8 29 5.7 0.1 6.4 7 0 0 7 7 7 2 WD domain, G-beta repeat Lactonase PF10282.9 OAG43216.1 - 0.023 14.0 0.0 0.089 12.0 0.0 2.0 2 0 0 2 2 2 0 Lactonase, 7-bladed beta-propeller TPR_1 PF00515.28 OAG43218.1 - 2.2e-09 36.8 0.2 0.005 16.6 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 OAG43218.1 - 5.8e-07 29.1 0.5 0.048 13.7 0.2 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 OAG43218.1 - 2.5e-06 27.1 0.3 0.042 14.0 0.1 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 OAG43218.1 - 0.00013 22.2 0.6 0.00098 19.4 0.7 2.2 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.6 OAG43218.1 - 0.00016 22.1 0.2 0.00043 20.7 0.2 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.6 OAG43218.1 - 0.00087 18.9 0.3 0.0045 16.6 0.1 2.2 2 0 0 2 2 2 1 TPR repeat TPR_14 PF13428.6 OAG43218.1 - 0.0049 17.6 0.3 0.39 11.6 0.1 2.8 1 1 1 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 OAG43218.1 - 0.068 13.4 1.1 0.22 11.8 1.1 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 OAG43218.1 - 0.09 13.4 0.3 0.37 11.5 0.3 2.0 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.6 OAG43218.1 - 0.17 12.6 0.3 12 6.8 0.2 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat ATP-synt_DE PF00401.20 OAG43218.1 - 1.4 9.3 5.5 3.1 8.1 2.3 2.5 2 0 0 2 2 2 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain HAD_2 PF13419.6 OAG43219.1 - 1.9e-14 54.1 0.0 3.8e-06 27.1 0.0 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OAG43219.1 - 2.5e-07 31.2 0.0 2.4e-06 28.0 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OAG43219.1 - 0.00086 19.3 0.0 0.0021 18.1 0.0 1.8 1 1 0 1 1 1 1 HAD-hyrolase-like zf-XS PF03470.14 OAG43219.1 - 1.6 9.1 3.6 0.43 10.9 0.4 1.7 2 0 0 2 2 2 0 XS zinc finger domain PQ-loop PF04193.14 OAG43220.1 - 4.5e-22 77.6 14.2 3.7e-11 42.6 1.9 3.5 3 0 0 3 3 3 2 PQ loop repeat ABC_tran_Xtn PF12848.7 OAG43222.1 - 0.062 13.3 6.8 0.093 12.8 6.8 1.2 1 0 0 1 1 1 0 ABC transporter DivIC PF04977.15 OAG43222.1 - 2.3 8.1 5.7 4.9 7.0 5.7 1.6 1 0 0 1 1 1 0 Septum formation initiator DUF2654 PF10849.8 OAG43222.1 - 2.8 8.2 5.8 0.82 9.9 2.9 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2654) Pkip-1 PF06878.11 OAG43223.1 - 0.26 11.4 0.8 0.51 10.4 0.8 1.5 1 1 1 2 2 2 0 Pkip-1 protein Sacchrp_dh_NADP PF03435.18 OAG43224.1 - 1e-11 45.2 0.0 1.7e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain ThiF PF00899.21 OAG43224.1 - 0.093 12.1 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 ThiF family Aldedh PF00171.22 OAG43225.1 - 1.7e-152 508.2 0.0 2.1e-152 507.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 OAG43225.1 - 0.14 11.2 0.1 0.3 10.1 0.1 1.5 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) Pkinase PF00069.25 OAG43226.1 - 1.5e-16 60.6 0.0 1.8e-16 60.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG43226.1 - 2.7e-07 30.2 0.0 3.9e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OAG43226.1 - 2.7e-05 24.2 1.1 9.2e-05 22.5 1.1 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 OAG43226.1 - 0.00036 19.9 0.0 0.00038 19.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OAG43226.1 - 0.005 16.2 0.0 0.0076 15.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 OAG43226.1 - 0.13 11.8 0.0 3 7.4 0.0 2.0 1 1 0 2 2 2 0 Choline/ethanolamine kinase SnoaL_2 PF12680.7 OAG43227.1 - 0.0008 20.0 0.1 0.0012 19.4 0.1 1.4 1 0 0 1 1 1 1 SnoaL-like domain MFS_1 PF07690.16 OAG43228.1 - 8.4e-33 113.7 39.6 8.4e-33 113.7 39.6 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 OAG43228.1 - 0.038 12.4 5.5 0.061 11.7 5.5 1.2 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) DUF2205 PF10224.9 OAG43229.1 - 0.005 16.8 0.2 0.011 15.7 0.2 1.6 1 0 0 1 1 1 1 Short coiled-coil protein Syntaxin PF00804.25 OAG43229.1 - 0.023 14.4 1.1 0.031 14.0 1.1 1.3 1 0 0 1 1 1 0 Syntaxin FliJ PF02050.16 OAG43229.1 - 0.024 14.8 3.6 0.057 13.6 3.6 1.5 1 1 0 1 1 1 0 Flagellar FliJ protein DUF2951 PF11166.8 OAG43229.1 - 0.029 14.6 0.6 0.054 13.7 0.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2951) bZIP_2 PF07716.15 OAG43229.1 - 0.087 12.9 0.2 0.087 12.9 0.2 2.3 2 0 0 2 2 2 0 Basic region leucine zipper SOGA PF11365.8 OAG43229.1 - 0.13 13.4 3.4 0.097 13.8 1.5 1.8 1 1 1 2 2 2 0 Protein SOGA DUF444 PF04285.12 OAG43229.1 - 0.17 10.9 5.6 0.22 10.6 5.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF444) HIP1_clath_bdg PF16515.5 OAG43229.1 - 0.34 11.5 3.3 1.2 9.8 2.0 2.1 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 SlyX PF04102.12 OAG43229.1 - 0.35 11.5 3.2 17 6.1 0.0 2.5 3 0 0 3 3 3 0 SlyX DivIC PF04977.15 OAG43229.1 - 1.2 9.0 4.4 1.4 8.7 1.4 2.0 2 0 0 2 2 2 0 Septum formation initiator PI3Ka PF00613.20 OAG43230.1 - 3.9e-50 169.8 0.1 6.6e-50 169.1 0.1 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 OAG43230.1 - 2.8e-46 158.3 0.0 7.9e-32 111.0 0.0 3.2 3 1 1 4 4 4 2 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 OAG43230.1 - 4.4e-28 98.0 0.0 8.9e-28 97.0 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 Nse4_C PF08743.10 OAG43231.1 - 3.1e-30 104.3 0.0 3.1e-30 104.3 0.0 3.2 5 0 0 5 5 5 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.6 OAG43231.1 - 2.6e-15 56.2 0.1 2.6e-15 56.2 0.1 2.6 2 0 0 2 2 2 1 Binding domain of Nse4/EID3 to Nse3-MAGE Ribosomal_60s PF00428.19 OAG43231.1 - 3.1 8.5 8.3 4.3e+02 1.6 0.0 2.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein MFS_1 PF07690.16 OAG43232.1 - 2.2e-30 105.8 20.0 2.2e-30 105.8 20.0 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Pyr_redox_2 PF07992.14 OAG43233.1 - 7.7e-56 189.5 0.6 1.8e-55 188.3 0.4 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 OAG43233.1 - 4.2e-31 107.5 0.1 9.8e-31 106.3 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 OAG43233.1 - 1.4e-15 57.6 0.1 1.4e-15 57.6 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG43233.1 - 7.4e-07 28.7 0.1 7.4e-07 28.7 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG43233.1 - 0.037 13.2 0.0 0.06 12.5 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.22 OAG43233.1 - 0.05 12.7 2.2 0.093 11.8 1.0 2.1 3 1 0 3 3 3 0 Glucose inhibited division protein A FAD_oxidored PF12831.7 OAG43233.1 - 0.2 11.0 0.3 0.28 10.5 0.3 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.17 OAG43233.1 - 0.62 9.3 3.2 0.53 9.5 1.7 1.6 2 0 0 2 2 2 0 Thi4 family FAD_binding_2 PF00890.24 OAG43233.1 - 2.8 6.9 5.5 16 4.4 2.9 2.4 3 0 0 3 3 3 0 FAD binding domain ECH_1 PF00378.20 OAG43234.1 - 1e-39 136.3 0.0 1.9e-39 135.5 0.0 1.3 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAG43234.1 - 6.9e-25 88.2 0.1 4.7e-23 82.2 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Ribosomal_L7Ae PF01248.26 OAG43236.1 - 3.2e-27 94.1 0.1 4e-27 93.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 OAG43236.1 - 0.0021 17.9 0.0 0.0028 17.5 0.0 1.2 1 0 0 1 1 1 1 PELOTA RNA binding domain ATP-synt_C PF00137.21 OAG43237.1 - 2.1e-34 117.6 33.3 6.9e-22 77.6 14.8 2.1 2 0 0 2 2 2 2 ATP synthase subunit C DUF2970 PF11174.8 OAG43237.1 - 4.9 7.1 10.5 1.3 8.9 1.7 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) DUF1713 PF08213.11 OAG43239.1 - 1.6e-12 47.1 18.2 3e-12 46.2 18.2 1.5 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) Pet20 PF08692.10 OAG43239.1 - 0.1 13.3 1.4 0.27 11.9 0.1 2.2 2 0 0 2 2 2 0 Mitochondrial protein Pet20 Dabb PF07876.12 OAG43240.1 - 2.7e-10 40.7 0.1 3e-10 40.6 0.1 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain DASH_Spc34 PF08657.10 OAG43240.1 - 0.033 14.0 0.1 0.036 13.8 0.1 1.0 1 0 0 1 1 1 0 DASH complex subunit Spc34 Ank_4 PF13637.6 OAG43241.1 - 2.9e-08 34.1 0.2 0.1 13.2 0.0 5.2 4 2 1 5 5 5 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 OAG43241.1 - 1.4e-06 28.8 0.0 0.0026 18.3 0.0 3.4 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OAG43241.1 - 4.2e-05 23.6 0.1 0.058 14.0 0.0 4.5 4 0 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.6 OAG43241.1 - 0.011 16.1 0.1 51 4.4 0.0 4.4 4 1 0 4 4 4 0 Ankyrin repeats (many copies) JAKMIP_CC3 PF16034.5 OAG43241.1 - 0.07 13.1 0.2 0.2 11.6 0.2 1.7 1 0 0 1 1 1 0 JAKMIP CC3 domain LXG PF04740.12 OAG43241.1 - 0.085 12.6 2.1 0.18 11.5 2.1 1.4 1 0 0 1 1 1 0 LXG domain of WXG superfamily DUF1664 PF07889.12 OAG43241.1 - 0.22 11.6 1.2 0.56 10.2 0.5 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Fez1 PF06818.15 OAG43241.1 - 2.6 8.4 4.3 11 6.3 4.4 1.9 1 1 0 1 1 1 0 Fez1 ThiF PF00899.21 OAG43242.1 - 8.8e-42 143.1 0.0 1.6e-41 142.3 0.0 1.3 1 0 0 1 1 1 1 ThiF family TrkA_N PF02254.18 OAG43242.1 - 0.0058 16.9 0.8 0.029 14.6 0.1 2.4 3 0 0 3 3 3 1 TrkA-N domain UDPG_MGDP_dh_N PF03721.14 OAG43242.1 - 0.0059 16.2 0.1 0.014 15.0 0.1 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Sacchrp_dh_NADP PF03435.18 OAG43242.1 - 0.022 15.0 1.9 0.37 11.1 0.1 2.8 3 0 0 3 3 3 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_7 PF13241.6 OAG43242.1 - 0.069 13.6 0.1 0.16 12.4 0.1 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Isy1 PF06246.12 OAG43243.1 - 3.2e-86 289.0 1.1 3.7e-86 288.9 1.1 1.0 1 0 0 1 1 1 1 Isy1-like splicing family CAP59_mtransfer PF11735.8 OAG43245.1 - 9e-79 264.6 0.0 1.3e-78 264.0 0.0 1.2 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 MaoC_dehydratas PF01575.19 OAG43246.1 - 0.0031 17.1 0.0 0.0055 16.3 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain DUF5035 PF16438.5 OAG43246.1 - 0.18 11.7 0.0 0.32 10.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5035) CENP-T_C PF15511.6 OAG43247.1 - 4.2e-34 116.9 0.1 8.6e-34 115.9 0.1 1.5 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 OAG43247.1 - 1e-07 32.2 0.0 2e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 CENP-S protein Histone PF00125.24 OAG43247.1 - 0.0012 19.2 0.1 0.0012 19.2 0.1 2.5 2 1 0 2 2 2 1 Core histone H2A/H2B/H3/H4 SURF1 PF02104.15 OAG43248.1 - 7.7e-44 150.0 0.0 9.8e-44 149.7 0.0 1.1 1 0 0 1 1 1 1 SURF1 family UBX PF00789.20 OAG43249.1 - 7.1e-09 35.7 0.0 1.7e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 UBX domain Elongin_A PF06881.11 OAG43249.1 - 0.024 15.2 1.7 0.057 14.0 1.7 1.5 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A TFB6 PF17110.5 OAG43251.1 - 3.7e-38 131.0 0.0 4.6e-38 130.6 0.0 1.1 1 0 0 1 1 1 1 Subunit 11 of the general transcription factor TFIIH Ribosomal_60s PF00428.19 OAG43251.1 - 0.15 12.6 0.2 0.15 12.6 0.2 1.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein Amidohydro_2 PF04909.14 OAG43252.1 - 1.1e-24 87.7 0.3 2.9e-24 86.4 0.3 1.7 1 1 0 1 1 1 1 Amidohydrolase adh_short_C2 PF13561.6 OAG43253.1 - 7.2e-52 176.3 0.0 4.6e-47 160.5 0.0 2.1 1 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG43253.1 - 8.6e-38 129.7 0.0 1.7e-31 109.2 0.0 2.0 1 1 1 2 2 2 2 short chain dehydrogenase KR PF08659.10 OAG43253.1 - 4.8e-09 36.4 0.1 1.8e-08 34.5 0.1 1.8 1 1 0 1 1 1 1 KR domain Fungal_trans PF04082.18 OAG43254.1 - 5.8e-20 71.4 0.0 9.1e-20 70.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain MR_MLE_C PF13378.6 OAG43255.1 - 2.1e-39 135.4 0.0 2.9e-39 134.9 0.0 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 OAG43255.1 - 1.1e-09 38.5 0.0 1.8e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Aldo_ket_red PF00248.21 OAG43256.1 - 9e-09 34.9 0.0 6.5e-05 22.3 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family NmrA PF05368.13 OAG43257.1 - 9.2e-26 90.8 0.0 1.1e-25 90.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG43257.1 - 5.5e-15 55.7 0.2 8.6e-14 51.8 0.0 2.3 2 1 0 2 2 2 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 OAG43257.1 - 1.4e-06 28.8 0.1 2.7e-06 27.8 0.0 1.6 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 OAG43257.1 - 2.7e-06 27.7 0.3 1.1e-05 25.7 0.0 1.9 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 OAG43257.1 - 0.0019 17.7 0.1 0.0054 16.2 0.0 1.9 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.10 OAG43257.1 - 0.0027 17.6 0.0 0.006 16.5 0.0 1.6 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.20 OAG43257.1 - 0.0079 16.3 0.0 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DapB_N PF01113.20 OAG43257.1 - 0.0083 16.2 0.3 0.023 14.8 0.0 1.8 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus NAD_binding_4 PF07993.12 OAG43257.1 - 0.018 14.2 0.0 0.034 13.3 0.0 1.4 1 0 0 1 1 1 0 Male sterility protein DUF4398 PF14346.6 OAG43257.1 - 0.03 14.9 2.3 0.05 14.2 2.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4398) MFS_1 PF07690.16 OAG43259.1 - 1.3e-36 126.2 49.6 1.3e-36 126.2 49.6 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 OAG43259.1 - 7.3e-16 57.7 27.0 1.1e-15 57.1 27.0 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Pyr_redox_3 PF13738.6 OAG43260.1 - 4.4e-17 62.3 0.0 4.3e-09 36.1 0.0 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAG43260.1 - 7.8e-12 45.0 0.0 3.5e-09 36.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 OAG43260.1 - 3.1e-11 42.4 0.0 1.9e-10 39.8 0.0 2.0 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 OAG43260.1 - 8.5e-09 35.0 0.0 1.9e-07 30.6 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 OAG43260.1 - 5.1e-05 22.7 1.7 0.007 15.7 0.6 2.3 1 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 OAG43260.1 - 0.00024 21.3 0.0 0.00084 19.5 0.0 2.0 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 OAG43260.1 - 0.0028 16.4 0.2 0.029 13.1 0.1 2.0 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.24 OAG43260.1 - 0.0043 16.7 3.6 0.15 11.6 0.7 2.6 2 1 0 3 3 3 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 OAG43260.1 - 0.016 14.5 0.0 0.29 10.4 0.0 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 OAG43260.1 - 0.033 13.3 0.6 0.11 11.5 0.1 2.1 3 0 0 3 3 3 0 Lycopene cyclase protein FAD_binding_2 PF00890.24 OAG43260.1 - 0.036 13.1 1.7 0.079 12.0 0.3 2.1 2 0 0 2 2 2 0 FAD binding domain Pyr_redox PF00070.27 OAG43260.1 - 0.046 14.3 0.2 5.2 7.7 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase LAM_C PF12544.8 OAG43260.1 - 0.07 13.3 0.1 0.25 11.5 0.1 1.9 1 0 0 1 1 1 0 Lysine-2,3-aminomutase Thi4 PF01946.17 OAG43260.1 - 0.15 11.3 0.0 1 8.5 0.1 2.0 2 0 0 2 2 2 0 Thi4 family TrkA_N PF02254.18 OAG43260.1 - 0.18 12.1 0.3 1.5 9.1 0.1 2.3 2 0 0 2 2 2 0 TrkA-N domain Pyr_redox_2 PF07992.14 OAG43261.1 - 8.1e-51 173.0 1.3 9.9e-51 172.7 1.3 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 OAG43261.1 - 4e-27 94.6 0.1 1.1e-26 93.2 0.0 1.7 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 OAG43261.1 - 9.2e-19 67.8 2.2 5.3e-17 62.2 0.2 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OAG43261.1 - 4.7e-08 32.5 0.4 0.0051 16.0 0.1 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 OAG43261.1 - 6.3e-07 29.0 0.6 4.6e-06 26.1 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG43261.1 - 1.3e-05 25.3 0.9 0.14 12.4 0.0 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 OAG43261.1 - 8e-05 22.2 1.3 0.022 14.1 0.3 2.4 3 0 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 OAG43261.1 - 0.00024 20.4 1.0 0.44 9.7 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain XdhC_C PF13478.6 OAG43261.1 - 0.00032 21.2 0.1 0.012 16.1 0.0 2.4 2 0 0 2 2 2 1 XdhC Rossmann domain 3HCDH_N PF02737.18 OAG43261.1 - 0.00055 19.9 1.1 0.076 12.9 0.1 2.3 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 OAG43261.1 - 0.0012 18.2 0.3 0.0065 15.8 0.0 2.2 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain K_oxygenase PF13434.6 OAG43261.1 - 0.0019 17.4 0.3 0.16 11.1 0.0 2.8 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) ThiF PF00899.21 OAG43261.1 - 0.0073 15.7 1.0 0.16 11.3 0.1 2.3 2 0 0 2 2 2 1 ThiF family FAD_binding_2 PF00890.24 OAG43261.1 - 0.024 13.7 2.2 0.36 9.8 1.8 2.4 2 0 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.12 OAG43261.1 - 0.027 13.6 2.4 0.34 9.9 0.1 3.0 2 1 1 3 3 3 0 Lycopene cyclase protein NAD_binding_7 PF13241.6 OAG43261.1 - 0.032 14.7 0.4 0.22 12.0 0.1 2.2 2 0 0 2 2 2 0 Putative NAD(P)-binding AlaDh_PNT_C PF01262.21 OAG43261.1 - 0.033 13.5 1.1 0.049 12.9 0.1 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.16 OAG43261.1 - 0.036 13.7 0.5 0.24 11.0 0.0 2.2 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 OAG43261.1 - 0.091 13.0 0.7 3.6 7.9 0.0 2.8 3 0 0 3 3 2 0 TrkA-N domain DFP PF04127.15 OAG43261.1 - 0.12 12.2 0.2 8.3 6.2 0.0 2.4 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein HI0933_like PF03486.14 OAG43261.1 - 0.14 10.8 4.5 0.97 8.1 0.1 2.9 2 1 1 3 3 3 0 HI0933-like protein An_peroxidase PF03098.15 OAG43262.1 - 3.9e-39 134.6 0.0 1e-28 100.2 0.0 3.7 1 1 1 2 2 2 2 Animal haem peroxidase p450 PF00067.22 OAG43262.1 - 7.9e-08 31.5 0.0 1.4e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 Ribosomal_L14 PF00238.19 OAG43263.1 - 2.7e-34 117.9 0.0 3.3e-34 117.6 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Fungal_trans_2 PF11951.8 OAG43264.1 - 1e-06 27.8 0.8 1.4e-06 27.4 0.8 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Peptidase_C12 PF01088.21 OAG43266.1 - 5.2e-68 228.9 0.0 7.6e-68 228.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 OAG43266.1 - 2.1e-09 37.1 0.1 4.4e-09 36.1 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases zf-C2H2_4 PF13894.6 OAG43267.1 - 1.7e-06 28.4 1.7 0.021 15.6 0.1 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 OAG43267.1 - 0.0016 18.8 2.7 0.033 14.6 0.1 2.9 2 0 0 2 2 2 1 Zinc finger, C2H2 type LicD PF04991.13 OAG43267.1 - 0.061 13.5 0.0 0.16 12.0 0.0 1.7 1 0 0 1 1 1 0 LicD family HEAT_EZ PF13513.6 OAG43268.1 - 5.5e-31 106.6 7.9 7.1e-16 58.3 0.1 10.0 9 2 2 11 11 11 4 HEAT-like repeat HEAT PF02985.22 OAG43268.1 - 1.3e-21 74.8 14.8 9.7e-05 22.3 0.1 9.5 11 0 0 11 11 9 4 HEAT repeat HEAT_2 PF13646.6 OAG43268.1 - 6.8e-18 64.8 2.1 3.2e-05 24.3 0.0 6.7 4 2 3 8 8 8 2 HEAT repeats Vac14_Fab1_bd PF12755.7 OAG43268.1 - 3.3e-10 40.4 0.0 0.047 14.3 0.0 5.8 4 2 2 6 6 5 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 OAG43268.1 - 3.6e-08 33.6 0.0 0.0011 19.1 0.0 4.6 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 MMS19_C PF12460.8 OAG43268.1 - 3.1e-06 26.6 2.9 0.51 9.4 0.0 4.7 4 1 1 5 5 5 2 RNAPII transcription regulator C-terminal CLASP_N PF12348.8 OAG43268.1 - 1.6e-05 24.6 0.1 3.5 7.1 0.0 5.2 5 2 1 6 6 6 2 CLASP N terminal DRIM PF07539.12 OAG43268.1 - 1.9e-05 23.2 0.0 0.044 12.1 0.0 3.1 2 1 0 2 2 2 2 Down-regulated in metastasis IBN_N PF03810.19 OAG43268.1 - 3.5e-05 23.6 2.3 0.018 15.0 0.1 4.7 3 1 1 4 4 4 1 Importin-beta N-terminal domain Adaptin_N PF01602.20 OAG43268.1 - 0.00027 19.7 0.2 0.039 12.5 0.0 3.0 2 1 0 2 2 2 1 Adaptin N terminal region RTP1_C1 PF10363.9 OAG43268.1 - 0.00052 20.2 0.4 0.047 13.9 0.0 3.3 4 0 0 4 4 3 1 Required for nuclear transport of RNA pol II C-terminus 1 Arm PF00514.23 OAG43268.1 - 0.016 15.2 2.8 1 9.5 0.0 4.7 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat HEAT_PBS PF03130.16 OAG43268.1 - 0.036 14.7 6.8 3.7 8.5 0.0 5.4 6 0 0 6 6 3 0 PBS lyase HEAT-like repeat RIX1 PF08167.12 OAG43268.1 - 0.038 13.7 0.2 11 5.7 0.0 4.4 5 1 0 5 5 5 0 rRNA processing/ribosome biogenesis CRISPR_Cse2 PF09485.10 OAG43268.1 - 0.058 13.9 0.2 0.44 11.1 0.1 2.6 2 0 0 2 2 2 0 CRISPR-associated protein Cse2 (CRISPR_cse2) Proteasom_PSMB PF10508.9 OAG43268.1 - 0.064 11.8 0.1 0.15 10.5 0.0 1.5 2 0 0 2 2 2 0 Proteasome non-ATPase 26S subunit TAF6_C PF07571.13 OAG43268.1 - 0.14 12.5 0.0 8.5 6.8 0.0 3.3 3 0 0 3 3 2 0 TAF6 C-terminal HEAT repeat domain DUF3437 PF11919.8 OAG43268.1 - 0.15 12.0 0.0 0.65 9.9 0.0 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3437) Syja_N PF02383.18 OAG43269.1 - 4.1e-91 305.6 0.0 6.3e-91 305.0 0.0 1.3 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.8 OAG43269.1 - 1.1e-36 125.0 0.0 2.6e-36 123.8 0.0 1.6 1 0 0 1 1 1 1 Inositol phosphatase Pkinase PF00069.25 OAG43270.1 - 2.8e-52 177.7 0.0 8.8e-50 169.5 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAG43270.1 - 5.8e-29 101.1 0.0 4.2e-28 98.4 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAG43270.1 - 0.0044 16.4 0.0 0.0066 15.8 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 OAG43270.1 - 0.0046 16.1 0.1 0.0077 15.3 0.1 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Haspin_kinase PF12330.8 OAG43270.1 - 0.044 12.7 0.0 0.064 12.2 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Sec_GG PF07549.14 OAG43270.1 - 0.23 11.0 1.4 0.34 10.5 0.2 2.0 2 0 0 2 2 2 0 SecD/SecF GG Motif Mem_trans PF03547.18 OAG43271.1 - 7.5e-51 172.7 5.5 8.6e-50 169.2 5.5 1.9 1 1 0 1 1 1 1 Membrane transport protein ADH_zinc_N_2 PF13602.6 OAG43272.1 - 3.4e-16 60.5 0.0 8.3e-16 59.2 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 OAG43272.1 - 1.8e-06 28.0 0.0 4.9e-06 26.6 0.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase DXP_reductoisom PF02670.16 OAG43272.1 - 0.0051 17.5 0.0 0.0079 16.9 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase Hist_deacetyl PF00850.19 OAG43273.1 - 1.8e-80 270.7 0.1 6.7e-80 268.8 0.0 1.8 2 0 0 2 2 2 1 Histone deacetylase domain JAB PF01398.21 OAG43274.1 - 4.8e-32 110.4 0.0 7.6e-32 109.8 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 OAG43274.1 - 5e-12 46.2 0.3 1.1e-11 45.2 0.3 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 OAG43274.1 - 4.4e-07 29.7 0.0 8.7e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain DUF4570 PF15134.6 OAG43274.1 - 0.051 13.6 0.1 0.097 12.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4570) NIF PF03031.18 OAG43276.1 - 5.2e-38 130.3 0.0 7.6e-38 129.7 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase F-box-like PF12937.7 OAG43277.1 - 0.041 13.8 0.2 0.085 12.8 0.2 1.6 1 0 0 1 1 1 0 F-box-like 2-Hacid_dh_C PF02826.19 OAG43278.1 - 1.8e-42 144.7 0.0 2.8e-42 144.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 OAG43278.1 - 1.3e-06 28.1 0.0 2.8e-06 27.0 0.0 1.6 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain XdhC_C PF13478.6 OAG43278.1 - 0.027 15.0 0.1 0.072 13.6 0.0 1.7 2 0 0 2 2 2 0 XdhC Rossmann domain NAD_binding_7 PF13241.6 OAG43278.1 - 0.1 13.1 0.0 0.49 10.9 0.0 2.1 2 0 0 2 2 2 0 Putative NAD(P)-binding TrkH PF02386.16 OAG43279.1 - 5.2e-91 305.6 2.7 1e-86 291.4 0.2 2.1 2 0 0 2 2 2 2 Cation transport protein DUF2470 PF10615.9 OAG43279.1 - 8.8e-23 80.7 1.1 1.9e-22 79.7 1.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) TauD PF02668.16 OAG43280.1 - 6.7e-34 117.9 0.1 9.1e-34 117.5 0.1 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family AA_permease_2 PF13520.6 OAG43281.1 - 4.6e-73 246.5 34.9 5.7e-73 246.2 34.9 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAG43281.1 - 2.9e-19 69.0 33.4 3.8e-19 68.7 33.4 1.1 1 0 0 1 1 1 1 Amino acid permease SafA PF17073.5 OAG43281.1 - 0.046 13.7 1.7 4.1 7.4 0.0 2.4 2 0 0 2 2 2 0 Two-component-system connector protein PH_10 PF15411.6 OAG43282.1 - 1.3e-32 112.7 0.0 2.6e-32 111.6 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.20 OAG43282.1 - 6.4e-29 101.5 1.3 1.1e-28 100.7 1.3 1.4 1 0 0 1 1 1 1 RhoGEF domain CDC24 PF06395.11 OAG43282.1 - 3.4e-27 94.5 0.0 6e-27 93.7 0.0 1.4 1 0 0 1 1 1 1 CDC24 Calponin PB1 PF00564.24 OAG43282.1 - 3.8e-08 33.1 0.0 1.3e-07 31.5 0.0 1.9 1 0 0 1 1 1 1 PB1 domain CH PF00307.31 OAG43282.1 - 0.063 13.5 0.0 0.28 11.4 0.0 2.1 2 0 0 2 2 2 0 Calponin homology (CH) domain PH PF00169.29 OAG43282.1 - 0.099 13.2 0.0 0.21 12.1 0.0 1.5 1 0 0 1 1 1 0 PH domain Abhydrolase_3 PF07859.13 OAG43283.1 - 1.8e-48 165.2 0.0 2.4e-48 164.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 OAG43283.1 - 2.4e-06 26.7 0.1 7.5e-06 25.1 0.1 1.6 1 1 0 1 1 1 1 Carboxylesterase family Mac-1 PF09028.10 OAG43283.1 - 0.26 10.3 0.0 0.37 9.8 0.0 1.1 1 0 0 1 1 1 0 Mac 1 Utp11 PF03998.13 OAG43284.1 - 4.9e-54 183.9 22.7 6.7e-54 183.4 22.7 1.2 1 0 0 1 1 1 1 Utp11 protein Syntaxin-6_N PF09177.11 OAG43284.1 - 0.032 14.8 1.6 0.06 13.9 0.6 2.0 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Cmc1 PF08583.10 OAG43285.1 - 1.9e-18 66.2 0.9 1.9e-18 66.2 0.9 2.2 2 1 0 2 2 2 1 Cytochrome c oxidase biogenesis protein Cmc1 like DFF40 PF09230.10 OAG43285.1 - 0.038 13.6 3.6 0.049 13.2 3.6 1.4 1 0 0 1 1 1 0 DNA fragmentation factor 40 kDa CAF1 PF04857.20 OAG43285.1 - 1.6 7.8 4.8 2.2 7.3 4.8 1.1 1 0 0 1 1 1 0 CAF1 family ribonuclease Aminotran_3 PF00202.21 OAG43287.1 - 3.3e-49 167.7 0.0 1.1e-48 165.9 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 OAG43287.1 - 0.039 13.1 0.0 0.057 12.6 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II Aminotran_1_2 PF00155.21 OAG43288.1 - 6.9e-32 111.0 0.0 1.5e-30 106.6 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class I and II SOBP PF15279.6 OAG43289.1 - 0.053 14.1 18.1 0.06 14.0 18.1 1.0 1 0 0 1 1 1 0 Sine oculis-binding protein Presenilin PF01080.17 OAG43289.1 - 0.23 10.2 7.8 0.22 10.2 7.8 1.1 1 0 0 1 1 1 0 Presenilin Mfa1 PF17445.2 OAG43289.1 - 0.28 11.3 10.6 2.8 8.1 0.9 2.6 2 0 0 2 2 2 0 Mating factor A1 TFIIA PF03153.13 OAG43289.1 - 1.2 9.1 17.1 1.4 8.8 17.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Raftlin PF15250.6 OAG43289.1 - 2.8 6.6 6.6 3.4 6.3 6.6 1.1 1 0 0 1 1 1 0 Raftlin LAP1C PF05609.12 OAG43289.1 - 3.7 6.6 10.8 4.1 6.4 10.8 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) GREB1 PF15782.5 OAG43289.1 - 5.5 4.0 6.5 6 3.8 6.5 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer TrmE_N PF10396.9 OAG43290.1 - 3.1e-31 108.1 0.0 1e-30 106.4 0.0 1.9 2 0 0 2 2 2 1 GTP-binding protein TrmE N-terminus MnmE_helical PF12631.7 OAG43290.1 - 6.5e-31 108.1 0.0 5.2e-29 101.9 0.0 2.2 1 1 0 1 1 1 1 MnmE helical domain MMR_HSR1 PF01926.23 OAG43290.1 - 1.6e-17 63.6 0.0 3e-17 62.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 OAG43290.1 - 8.7e-06 25.9 0.0 5.2e-05 23.4 0.0 2.1 1 1 1 2 2 2 1 Dynamin family FeoB_N PF02421.18 OAG43290.1 - 0.00051 19.6 0.0 0.0011 18.5 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 OAG43290.1 - 0.0022 17.6 0.0 1.6 8.2 0.0 2.3 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OAG43290.1 - 0.022 14.7 0.0 0.52 10.2 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase DUF3678 PF12435.8 OAG43290.1 - 6.9 6.1 5.8 0.79 9.2 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3678) CAP PF00188.26 OAG43293.1 - 6.9e-16 59.2 0.1 1e-15 58.7 0.1 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family MFS_1 PF07690.16 OAG43294.1 - 2.5e-44 151.6 18.9 6.8e-38 130.5 9.4 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG43294.1 - 6.7e-09 35.1 8.4 6.7e-09 35.1 8.4 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 OAG43294.1 - 0.0011 18.3 5.9 0.0011 18.3 5.9 2.1 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB MFS_5 PF05631.14 OAG43294.1 - 0.025 13.5 3.2 0.019 13.9 1.9 1.4 2 0 0 2 2 2 0 Sugar-tranasporters, 12 TM OATP PF03137.20 OAG43294.1 - 0.033 12.5 3.0 0.17 10.1 2.6 2.2 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF5401 PF17380.2 OAG43294.1 - 0.6 8.1 5.6 0.84 7.6 5.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) MFS_3 PF05977.13 OAG43294.1 - 0.83 8.0 7.6 0.18 10.2 3.9 1.7 2 0 0 2 2 2 0 Transmembrane secretion effector Stn1 PF10451.9 OAG43295.1 - 2.1e-11 43.3 0.0 1.8e-09 36.9 0.0 2.3 2 0 0 2 2 2 2 Telomere regulation protein Stn1 tRNA_anti-codon PF01336.25 OAG43295.1 - 0.00092 19.2 0.0 0.021 14.8 0.0 2.2 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain TRAP-gamma PF07074.12 OAG43295.1 - 0.13 11.9 0.2 0.19 11.3 0.2 1.3 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) MIF4G PF02854.19 OAG43296.1 - 1.7e-50 171.6 0.0 2.9e-50 170.9 0.0 1.4 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.8 OAG43296.1 - 1.4e-23 82.9 0.7 4.5e-23 81.2 0.7 2.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 Borrelia_P83 PF05262.11 OAG43296.1 - 0.23 9.9 37.1 0.45 8.9 37.1 1.5 1 0 0 1 1 1 0 Borrelia P83/100 protein DnaJ PF00226.31 OAG43297.1 - 1.5e-23 82.7 2.3 4.4e-23 81.2 2.3 1.9 1 0 0 1 1 1 1 DnaJ domain Imm49 PF15575.6 OAG43297.1 - 3.6 7.3 7.1 0.77 9.5 1.7 2.5 2 1 1 3 3 3 0 Immunity protein 49 SseC PF04888.12 OAG43299.1 - 8.4 5.9 6.9 13 5.3 6.9 1.2 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Usp PF00582.26 OAG43300.1 - 2.9e-17 63.5 5.0 1.9e-16 60.9 0.7 3.2 2 1 0 2 2 2 1 Universal stress protein family GCIP PF13324.6 OAG43300.1 - 0.51 9.9 3.9 2.6 7.6 0.0 2.2 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting Inv-AAD PF18785.1 OAG43301.1 - 5.2e-34 116.9 0.0 1.3e-33 115.6 0.0 1.6 1 1 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase dCMP_cyt_deam_1 PF00383.23 OAG43301.1 - 1.1e-14 54.1 0.0 4.9e-14 52.0 0.0 1.9 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region WD40 PF00400.32 OAG43302.1 - 1.7e-15 57.1 12.0 0.16 12.9 0.0 8.7 9 0 0 9 9 9 5 WD domain, G-beta repeat PQQ PF01011.21 OAG43302.1 - 0.0038 17.1 0.0 0.02 14.8 0.0 2.3 2 0 0 2 2 2 1 PQQ enzyme repeat WD40_like PF17005.5 OAG43302.1 - 0.079 12.3 0.4 4.8 6.4 0.0 2.8 3 0 0 3 3 3 0 WD40-like domain DUF1840 PF08895.11 OAG43302.1 - 0.13 12.6 1.0 0.36 11.2 1.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) FGGY_N PF00370.21 OAG43303.1 - 0.071 12.7 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain AAA PF00004.29 OAG43304.1 - 0.0002 21.8 0.0 0.0003 21.2 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) bZIP_1 PF00170.21 OAG43305.1 - 2.9e-08 33.7 9.6 8.8e-08 32.1 6.9 2.2 1 1 1 2 2 2 2 bZIP transcription factor ASD2 PF08687.11 OAG43305.1 - 0.00016 21.3 1.0 0.0002 21.0 1.0 1.1 1 0 0 1 1 1 1 Apx/Shroom domain ASD2 CENP-F_leu_zip PF10473.9 OAG43305.1 - 0.00055 20.0 2.1 0.00078 19.5 2.1 1.2 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CEP63 PF17045.5 OAG43305.1 - 0.00068 19.6 3.4 0.00092 19.2 3.4 1.2 1 0 0 1 1 1 1 Centrosomal protein of 63 kDa TMF_TATA_bd PF12325.8 OAG43305.1 - 0.0028 17.8 2.1 0.0046 17.2 2.1 1.3 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding TolA_bind_tri PF16331.5 OAG43305.1 - 0.0031 17.5 3.7 0.0064 16.5 3.7 1.5 1 0 0 1 1 1 1 TolA binding protein trimerisation DUF4618 PF15397.6 OAG43305.1 - 0.0041 16.6 0.6 0.0058 16.1 0.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4618) DUF4094 PF13334.6 OAG43305.1 - 0.0052 17.2 0.9 0.0091 16.4 0.9 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4094) bZIP_2 PF07716.15 OAG43305.1 - 0.0069 16.4 7.4 0.0069 16.4 7.4 2.8 2 1 1 3 3 3 1 Basic region leucine zipper SHE3 PF17078.5 OAG43305.1 - 0.013 15.2 2.6 0.019 14.7 2.6 1.3 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 APG6_N PF17675.1 OAG43305.1 - 0.021 15.4 4.4 0.031 14.8 4.4 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region CLZ PF16526.5 OAG43305.1 - 0.024 15.0 3.6 0.048 14.0 3.6 1.5 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ABC_tran_CTD PF16326.5 OAG43305.1 - 0.056 13.7 1.4 0.11 12.8 1.4 1.4 1 0 0 1 1 1 0 ABC transporter C-terminal domain FlxA PF14282.6 OAG43305.1 - 0.059 13.4 1.3 0.18 11.8 1.3 1.8 1 1 0 1 1 1 0 FlxA-like protein DUF948 PF06103.11 OAG43305.1 - 0.15 12.3 0.1 0.23 11.7 0.1 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Jnk-SapK_ap_N PF09744.9 OAG43305.1 - 0.23 11.7 6.7 0.32 11.2 6.7 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Csm1_N PF18504.1 OAG43305.1 - 0.57 10.6 3.6 2 8.8 1.9 2.2 1 1 1 2 2 2 0 Csm1 N-terminal domain bZIP_Maf PF03131.17 OAG43305.1 - 0.72 10.4 14.1 0.059 13.9 8.9 1.9 1 1 1 2 2 2 0 bZIP Maf transcription factor DivIC PF04977.15 OAG43305.1 - 1.2 9.0 4.5 0.91 9.3 0.8 2.1 1 1 1 2 2 2 0 Septum formation initiator GvpL_GvpF PF06386.11 OAG43305.1 - 2.3 8.1 6.5 3.4 7.5 6.3 1.4 1 1 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF G-alpha PF00503.20 OAG43306.1 - 1.2e-110 370.0 3.1 1.5e-110 369.8 3.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 OAG43306.1 - 9.3e-14 51.3 0.7 1.3e-08 34.5 0.0 3.0 3 1 0 3 3 3 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OAG43306.1 - 0.00032 20.1 0.1 0.29 10.5 0.2 2.7 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 OAG43306.1 - 0.00077 19.7 1.2 0.82 9.9 0.0 3.6 2 1 1 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 OAG43306.1 - 0.0076 15.7 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 Bacterial TniB protein MMR_HSR1 PF01926.23 OAG43306.1 - 0.031 14.3 0.0 12 6.0 0.0 2.9 3 0 0 3 3 3 0 50S ribosome-binding GTPase AAA_29 PF13555.6 OAG43306.1 - 0.083 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 OAG43306.1 - 0.11 12.9 0.0 0.35 11.2 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain GSHPx PF00255.19 OAG43308.1 - 4.4e-37 126.0 0.1 5.5e-37 125.6 0.1 1.1 1 0 0 1 1 1 1 Glutathione peroxidase TMEM154 PF15102.6 OAG43309.1 - 0.00064 19.6 0.1 0.0017 18.3 0.0 1.6 1 1 1 2 2 2 1 TMEM154 protein family EphA2_TM PF14575.6 OAG43309.1 - 0.021 15.7 0.0 0.03 15.2 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain CcmD PF04995.14 OAG43309.1 - 0.043 13.9 0.5 0.06 13.4 0.5 1.2 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) DUF2269 PF10027.9 OAG43309.1 - 0.049 13.7 0.0 0.062 13.4 0.0 1.1 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2269) Orf78 PF06024.12 OAG43309.1 - 0.13 12.5 0.4 0.24 11.7 0.2 1.4 1 1 0 1 1 1 0 Orf78 (ac78) LNS2 PF08235.13 OAG43310.1 - 1.5e-94 315.7 0.0 2.2e-94 315.2 0.0 1.2 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 OAG43310.1 - 2.9e-41 139.6 0.0 6e-41 138.5 0.0 1.6 1 0 0 1 1 1 1 lipin, N-terminal conserved region Acid_phosphat_B PF03767.14 OAG43310.1 - 0.025 14.2 0.1 0.99 8.9 0.0 2.5 2 0 0 2 2 2 0 HAD superfamily, subfamily IIIB (Acid phosphatase) GCIP PF13324.6 OAG43310.1 - 1.6 8.2 8.9 2.8 7.5 8.9 1.3 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting TFIID-31kDa PF02291.15 OAG43311.1 - 4.9e-43 146.1 0.0 7e-43 145.6 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Asparaginase PF00710.20 OAG43312.1 - 1.2e-50 171.7 0.3 2.4e-50 170.7 0.3 1.4 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 OAG43312.1 - 6.3e-20 71.5 0.0 1.4e-18 67.1 0.0 2.6 3 0 0 3 3 3 1 Glutaminase/Asparaginase C-terminal domain fn3 PF00041.21 OAG43313.1 - 2.9e-06 27.5 0.1 1.1e-05 25.7 0.1 2.0 1 1 0 1 1 1 1 Fibronectin type III domain DUF5337 PF17272.2 OAG43313.1 - 0.0034 17.2 3.6 0.0072 16.1 3.6 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF5337) Pur_ac_phosph_N PF16656.5 OAG43313.1 - 0.12 13.0 0.8 1.5 9.4 0.0 3.1 2 1 0 2 2 2 0 Purple acid Phosphatase, N-terminal domain Thg1C PF14413.6 OAG43314.1 - 3.5e-51 172.5 6.8 4.1e-49 165.8 6.8 2.2 1 1 0 1 1 1 1 Thg1 C terminal domain Thg1 PF04446.12 OAG43314.1 - 3.1e-23 82.1 0.0 4.9e-23 81.5 0.0 1.3 1 0 0 1 1 1 1 tRNAHis guanylyltransferase GRA6 PF05084.13 OAG43314.1 - 0.12 12.3 9.2 0.083 12.8 4.9 2.2 2 1 0 2 2 2 0 Granule antigen protein (GRA6) CENP-I PF07778.11 OAG43314.1 - 0.84 8.3 6.2 1.2 7.8 6.2 1.1 1 0 0 1 1 1 0 Mis6 CRA PF06589.11 OAG43314.1 - 1.4 9.0 3.2 2.8 8.1 3.2 1.4 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) Afi1 PF07792.12 OAG43314.1 - 2.9 8.4 8.0 0.24 11.9 3.5 1.6 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Presenilin PF01080.17 OAG43314.1 - 4.6 5.9 5.4 5.9 5.6 5.4 1.2 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.12 OAG43314.1 - 8.8 6.1 12.9 0.24 11.2 6.7 1.4 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DUF3464 PF11947.8 OAG43314.1 - 8.9 6.1 7.6 16 5.3 7.6 1.4 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Aldedh PF00171.22 OAG43315.1 - 2.8e-116 388.8 0.5 3.5e-116 388.5 0.5 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF3425 PF11905.8 OAG43316.1 - 4.7e-24 84.7 1.1 8.9e-24 83.8 1.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 OAG43316.1 - 8e-05 22.7 6.2 0.00019 21.5 6.2 1.7 1 1 0 1 1 1 1 bZIP transcription factor Pil1 PF13805.6 OAG43316.1 - 0.0058 16.2 3.7 0.0088 15.6 3.7 1.2 1 0 0 1 1 1 1 Eisosome component PIL1 bZIP_2 PF07716.15 OAG43316.1 - 0.072 13.2 10.2 0.053 13.6 5.4 2.2 2 0 0 2 2 2 0 Basic region leucine zipper Latarcin PF10279.9 OAG43316.1 - 0.22 11.9 2.4 3.3 8.2 1.0 2.7 2 2 1 3 3 3 0 Latarcin precursor adh_short_C2 PF13561.6 OAG43317.1 - 8.3e-47 159.7 2.3 9.3e-32 110.4 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG43317.1 - 5.4e-41 140.2 0.7 2.2e-40 138.2 0.7 1.8 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG43317.1 - 1.1e-08 35.1 0.2 3.6e-08 33.5 0.0 1.8 2 0 0 2 2 2 1 KR domain 3Beta_HSD PF01073.19 OAG43317.1 - 0.0063 15.5 0.1 0.035 13.1 0.2 1.9 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.20 OAG43317.1 - 0.042 14.0 0.0 0.47 10.6 0.0 2.3 2 1 1 3 3 3 0 Dihydrodipicolinate reductase, N-terminus FMO-like PF00743.19 OAG43318.1 - 6.9e-19 67.7 0.3 7.1e-17 61.0 0.3 2.4 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OAG43318.1 - 1.2e-13 51.0 0.0 3e-13 49.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 OAG43318.1 - 4.5e-10 39.3 0.0 8.8e-09 35.0 0.1 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG43318.1 - 4.1e-08 32.8 0.0 5.6e-06 25.7 0.0 3.2 4 0 0 4 4 4 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 OAG43318.1 - 3e-05 23.4 0.0 0.00034 19.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAG43318.1 - 0.0002 20.7 0.1 0.012 14.8 0.1 2.5 2 1 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.6 OAG43318.1 - 0.004 17.2 0.0 0.044 13.8 0.0 2.6 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.24 OAG43318.1 - 0.036 13.6 0.1 0.35 10.4 0.1 2.6 1 1 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 OAG43318.1 - 0.096 11.4 0.1 0.17 10.6 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_2 PF00890.24 OAG43318.1 - 0.23 10.5 0.0 0.36 9.9 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain ADH_N PF08240.12 OAG43319.1 - 1.6e-28 98.8 1.5 1.6e-28 98.8 1.5 2.3 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG43319.1 - 1.3e-07 31.7 0.0 3.1e-05 23.9 0.0 2.4 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 OAG43319.1 - 6.9e-05 22.4 0.2 0.0043 16.6 0.0 2.2 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus ADH_N_assoc PF13823.6 OAG43319.1 - 0.0031 17.4 0.2 0.0065 16.4 0.2 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated CIAPIN1 PF05093.13 OAG43319.1 - 1.5 9.3 5.1 0.5 10.9 0.4 2.4 2 0 0 2 2 2 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DUF4381 PF14316.6 OAG43321.1 - 0.22 11.8 2.4 0.47 10.7 2.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) tRNA-synt_1d PF00750.19 OAG43322.1 - 6.5e-70 235.8 0.0 8.6e-70 235.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 OAG43322.1 - 2e-06 28.0 0.0 5.6e-06 26.5 0.0 1.8 1 0 0 1 1 1 1 DALR anticodon binding domain HeLo PF14479.6 OAG43322.1 - 0.018 14.9 0.1 0.038 13.8 0.1 1.5 1 0 0 1 1 1 0 Prion-inhibition and propagation DUF4473 PF14747.6 OAG43322.1 - 0.16 12.5 0.6 0.56 10.8 0.6 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4473) DUF2076 PF09849.9 OAG43324.1 - 0.26 11.3 8.2 0.33 11.0 8.2 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Pollen_allerg_2 PF01620.16 OAG43324.1 - 0.39 10.9 3.2 0.24 11.6 1.8 1.5 1 1 0 1 1 1 0 Ribonuclease (pollen allergen) CinA PF02464.17 OAG43325.1 - 1.1e-33 116.0 0.3 1.2e-33 115.9 0.3 1.0 1 0 0 1 1 1 1 Competence-damaged protein Sugar_tr PF00083.24 OAG43326.1 - 4.2e-78 263.2 23.7 4.9e-78 263.0 23.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG43326.1 - 2.3e-18 66.3 27.8 2.3e-18 66.3 27.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Ydc2-catalyt PF09159.10 OAG43327.1 - 1.3e-71 241.7 0.0 1.6e-71 241.3 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 ADH_N PF08240.12 OAG43327.1 - 4.3e-17 62.0 2.3 8.2e-17 61.1 2.3 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG43327.1 - 2.3e-09 37.3 0.0 4.6e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pox_A22 PF04848.13 OAG43327.1 - 6e-05 23.2 0.0 1 9.4 0.0 3.3 3 0 0 3 3 3 2 Poxvirus A22 protein 2-Hacid_dh_C PF02826.19 OAG43327.1 - 0.00047 19.6 0.1 0.001 18.4 0.1 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Malate_synthase PF01274.22 OAG43329.1 - 3e-227 755.1 0.0 3.3e-227 754.9 0.0 1.0 1 0 0 1 1 1 1 Malate synthase Epimerase PF01370.21 OAG43330.1 - 6.3e-17 61.8 0.0 8.7e-17 61.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAG43330.1 - 4e-10 39.6 0.0 9e-09 35.2 0.0 2.3 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 OAG43330.1 - 1.2e-09 37.6 0.0 1.6e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 OAG43330.1 - 6e-09 35.5 0.0 0.0026 16.9 0.0 2.6 2 1 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 OAG43330.1 - 6.1e-06 25.5 0.0 2.8e-05 23.4 0.0 2.0 1 1 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 OAG43330.1 - 0.022 13.9 0.0 0.14 11.2 0.0 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein KR PF08659.10 OAG43330.1 - 0.048 13.6 0.0 0.58 10.0 0.0 2.3 2 0 0 2 2 2 0 KR domain Ldh_1_N PF00056.23 OAG43330.1 - 0.078 13.1 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain adh_short PF00106.25 OAG43330.1 - 0.12 11.8 0.0 0.43 10.0 0.0 1.9 2 0 0 2 2 2 0 short chain dehydrogenase F_bP_aldolase PF01116.20 OAG43331.1 - 3.1e-75 253.3 0.0 3.7e-75 253.0 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Methyltransf_24 PF13578.6 OAG43331.1 - 0.033 15.2 0.0 0.068 14.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain CUE PF02845.16 OAG43332.1 - 8e-10 38.2 0.0 2.2e-09 36.8 0.0 1.8 2 0 0 2 2 2 1 CUE domain OB_NTP_bind PF07717.16 OAG43333.1 - 6.3e-14 52.1 0.0 1.9e-13 50.5 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 OAG43333.1 - 7.7e-13 48.8 0.0 2.2e-12 47.3 0.0 1.7 2 0 0 2 2 1 1 Helicase conserved C-terminal domain HA2 PF04408.23 OAG43333.1 - 1.9e-12 47.4 0.0 5.6e-12 45.9 0.0 1.8 2 0 0 2 2 1 1 Helicase associated domain (HA2) AAA_30 PF13604.6 OAG43333.1 - 3.5e-06 26.9 0.0 7.1e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 OAG43333.1 - 1.3e-05 25.5 0.1 3.6e-05 24.0 0.1 1.7 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 OAG43333.1 - 2.1e-05 24.3 0.1 5.2e-05 23.1 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 OAG43333.1 - 0.00014 22.2 0.1 0.00041 20.7 0.1 1.8 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 OAG43333.1 - 0.0023 18.4 0.1 0.12 12.9 0.1 2.6 1 1 0 1 1 1 1 ABC transporter AAA_14 PF13173.6 OAG43333.1 - 0.0073 16.3 0.2 1.1 9.3 0.0 2.5 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.17 OAG43333.1 - 0.0088 15.8 0.3 1 9.1 0.0 2.3 1 1 1 2 2 2 1 IstB-like ATP binding protein cobW PF02492.19 OAG43333.1 - 0.015 14.9 0.1 0.17 11.4 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Flavi_DEAD PF07652.14 OAG43333.1 - 0.018 15.0 0.0 0.034 14.1 0.0 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain DUF2075 PF09848.9 OAG43333.1 - 0.031 13.5 0.0 0.049 12.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.6 OAG43333.1 - 0.051 14.0 0.7 0.18 12.2 0.2 2.1 2 1 0 2 2 1 0 AAA ATPase domain AAA_33 PF13671.6 OAG43333.1 - 0.076 13.2 0.1 0.17 12.1 0.1 1.8 1 1 0 1 1 1 0 AAA domain T2SSE PF00437.20 OAG43333.1 - 0.082 12.0 0.1 0.16 11.0 0.1 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.6 OAG43333.1 - 0.089 12.6 0.1 0.19 11.5 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 OAG43333.1 - 0.14 12.7 0.1 0.31 11.5 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 OAG43333.1 - 0.14 11.9 0.0 1.7 8.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 OAG43333.1 - 0.17 11.3 0.0 0.38 10.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 OAG43333.1 - 0.19 11.0 0.5 0.67 9.2 0.1 2.0 1 1 1 2 2 2 0 Zeta toxin AAA PF00004.29 OAG43333.1 - 0.76 10.2 2.6 5.4 7.4 1.3 2.6 2 1 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) SRP54 PF00448.22 OAG43333.1 - 1.5 8.4 4.3 1.5 8.4 0.7 2.9 3 1 0 3 3 3 0 SRP54-type protein, GTPase domain DEAD PF00270.29 OAG43334.1 - 6e-16 58.7 0.0 1e-15 58.0 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAG43334.1 - 3.5e-14 53.1 0.0 1.7e-13 50.8 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 OAG43334.1 - 4.3e-09 37.0 9.4 1.6e-08 35.2 9.4 2.2 1 1 0 1 1 1 1 RecQ zinc-binding MmgE_PrpD PF03972.14 OAG43334.1 - 0.0042 15.7 0.0 0.0066 15.0 0.0 1.2 1 0 0 1 1 1 1 MmgE/PrpD family Fungal_trans_2 PF11951.8 OAG43335.1 - 0.00035 19.5 0.1 0.00047 19.1 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Peptidase_A22B PF04258.13 OAG43336.1 - 8.1e-62 209.3 3.2 3.1e-61 207.4 3.2 1.9 1 1 0 1 1 1 1 Signal peptide peptidase SPP PF06550.11 OAG43336.1 - 1.7e-07 31.0 8.0 3.7e-07 29.9 2.7 2.2 2 0 0 2 2 2 2 Signal-peptide peptidase, presenilin aspartyl protease WH1 PF00568.23 OAG43337.1 - 7.8e-29 99.9 0.2 1.1e-28 99.4 0.2 1.2 1 0 0 1 1 1 1 WH1 domain WH2 PF02205.20 OAG43337.1 - 0.1 12.5 4.6 0.59 10.1 4.6 2.3 1 1 0 1 1 1 0 WH2 motif CorA PF01544.18 OAG43338.1 - 3.7e-10 39.6 0.3 8.8e-10 38.4 0.3 1.5 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein AA_permease_2 PF13520.6 OAG43338.1 - 0.0078 15.1 0.1 0.011 14.6 0.1 1.1 1 0 0 1 1 1 1 Amino acid permease ApoL PF05461.11 OAG43338.1 - 0.0099 15.2 0.9 0.023 14.1 0.8 1.7 1 1 0 1 1 1 1 Apolipoprotein L Colicin_V PF02674.16 OAG43338.1 - 0.12 12.4 0.2 0.19 11.7 0.2 1.2 1 0 0 1 1 1 0 Colicin V production protein MFS_1 PF07690.16 OAG43339.1 - 1.7e-35 122.6 19.3 1.7e-35 122.6 19.3 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG43339.1 - 4.1e-11 42.4 6.4 4.1e-11 42.4 6.4 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter PTR2 PF00854.21 OAG43339.1 - 0.0074 15.2 0.6 0.012 14.4 0.6 1.3 1 0 0 1 1 1 1 POT family TRI12 PF06609.13 OAG43339.1 - 0.088 11.2 5.7 0.14 10.5 5.7 1.2 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) MOSC PF03473.17 OAG43340.1 - 9.3e-32 109.8 0.0 1.5e-31 109.1 0.0 1.4 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 OAG43340.1 - 3.3e-15 56.0 0.0 9e-15 54.6 0.0 1.8 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain BRCT_2 PF16589.5 OAG43341.1 - 2.4e-11 43.9 0.0 3.9e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 OAG43341.1 - 0.0043 17.3 0.0 0.0068 16.7 0.0 1.3 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain BRCT PF00533.26 OAG43341.1 - 0.0048 17.3 0.0 0.008 16.5 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 OAG43341.1 - 0.0067 16.3 1.4 0.009 15.9 0.1 1.9 2 0 0 2 2 2 1 twin BRCT domain Meth_synt_2 PF01717.18 OAG43342.1 - 7.6e-149 495.3 0.0 3.3e-145 483.4 0.0 2.2 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 OAG43342.1 - 4.1e-117 391.2 0.0 5.3e-111 371.1 0.0 2.9 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain VbhA PF18495.1 OAG43342.1 - 0.0093 15.8 1.5 6.6 6.7 0.0 3.6 4 0 0 4 4 4 2 Antitoxin VbhA Bac_small_YrzI PF09501.10 OAG43342.1 - 0.42 10.8 2.1 1.4 9.2 2.1 1.8 1 0 0 1 1 1 0 Probable sporulation protein (Bac_small_yrzI) SHOCT PF09851.9 OAG43342.1 - 1.3 8.9 6.0 0.49 10.2 0.2 3.1 3 0 0 3 3 3 0 Short C-terminal domain Steroid_dh PF02544.16 OAG43343.1 - 6.9e-12 45.6 1.5 3.9e-11 43.2 1.5 2.0 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 OAG43343.1 - 0.00039 20.0 2.7 0.00075 19.1 2.7 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) ALS_ss_C PF10369.9 OAG43344.1 - 1.3e-14 54.1 0.0 1.3e-13 51.0 0.0 2.2 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.25 OAG43344.1 - 1.2e-13 50.5 0.1 5.2e-13 48.5 0.1 2.1 2 0 0 2 2 2 1 ACT domain ACT_5 PF13710.6 OAG43344.1 - 4.2e-08 32.9 0.0 8.1e-08 32.0 0.0 1.5 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.6 OAG43344.1 - 0.071 13.1 0.0 13 5.9 0.0 2.5 2 0 0 2 2 2 0 ACT domain Glyco_hydro_28 PF00295.17 OAG43345.1 - 1.4e-32 113.1 10.1 1.4e-18 67.0 2.3 2.0 2 0 0 2 2 2 2 Glycosyl hydrolases family 28 Carb_anhydrase PF00194.21 OAG43346.1 - 3.8e-25 88.9 0.1 7.7e-25 87.9 0.1 1.5 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase DUF924 PF06041.11 OAG43347.1 - 2.3e-55 187.6 0.0 2.7e-55 187.3 0.0 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF924) DDE_3 PF13358.6 OAG43347.1 - 0.081 12.7 0.1 0.15 11.8 0.1 1.5 1 0 0 1 1 1 0 DDE superfamily endonuclease Aa_trans PF01490.18 OAG43348.1 - 2.9e-63 214.0 16.8 3.4e-63 213.8 16.8 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DotU PF09850.9 OAG43348.1 - 0.031 14.0 0.0 0.2 11.4 0.0 2.4 2 0 0 2 2 2 0 Type VI secretion system protein DotU MCR PF18509.1 OAG43348.1 - 0.12 11.9 0.6 0.23 11.1 0.6 1.4 1 0 0 1 1 1 0 Magnetochrome domain eRF1_2 PF03464.15 OAG43349.1 - 3.4e-48 163.3 0.1 6.2e-48 162.5 0.1 1.5 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 OAG43349.1 - 5.9e-39 133.1 0.5 1.3e-38 132.0 0.5 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 OAG43349.1 - 4.9e-21 75.1 0.0 7.9e-21 74.4 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 baeRF_family10 PF18854.1 OAG43349.1 - 1.5e-10 41.4 0.0 3e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 acVLRF1 PF18859.1 OAG43349.1 - 4.1e-10 40.1 0.1 7.1e-10 39.3 0.1 1.4 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor DUF3440 PF11922.8 OAG43349.1 - 0.13 11.9 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3440) PDT PF00800.18 OAG43350.1 - 4.2e-48 163.6 0.0 5.6e-48 163.2 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.25 OAG43350.1 - 3.9e-07 29.7 0.0 8.8e-07 28.6 0.0 1.6 1 0 0 1 1 1 1 ACT domain Creatinase_N_2 PF16189.5 OAG43352.1 - 2.8e-53 180.3 0.0 1.9e-52 177.6 0.0 2.2 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 OAG43352.1 - 4.8e-42 144.0 0.0 6.9e-42 143.5 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M24_C PF16188.5 OAG43352.1 - 6.4e-24 83.8 0.4 2.5e-23 81.9 0.4 2.1 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 OAG43352.1 - 6.3e-22 78.6 0.0 7.7e-20 71.9 0.0 2.3 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain IBN_N PF03810.19 OAG43353.1 - 3.2e-05 23.7 0.2 0.00013 21.8 0.2 2.1 1 0 0 1 1 1 1 Importin-beta N-terminal domain Importin_rep_3 PF18806.1 OAG43353.1 - 0.00069 19.6 0.0 0.0051 16.8 0.0 2.6 2 0 0 2 2 2 1 Importin 13 repeat Xpo1 PF08389.12 OAG43353.1 - 0.005 16.9 0.3 0.11 12.6 0.0 3.5 3 0 0 3 3 3 1 Exportin 1-like protein Importin_rep PF18773.1 OAG43353.1 - 0.0077 15.9 1.7 0.0099 15.6 0.3 1.9 2 0 0 2 2 2 1 Importin 13 repeat EH_Signature PF15611.6 OAG43353.1 - 0.013 15.0 0.1 0.026 14.0 0.1 1.5 1 0 0 1 1 1 0 EH_Signature domain CamS PF07537.11 OAG43353.1 - 0.19 10.9 0.0 0.33 10.0 0.0 1.4 1 0 0 1 1 1 0 CamS sex pheromone cAM373 precursor Sec8_exocyst PF04048.14 OAG43354.1 - 1.2e-37 128.9 0.0 3.3e-37 127.5 0.0 1.8 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain Vps54_N PF10475.9 OAG43354.1 - 2.4e-08 33.6 0.1 4.9e-08 32.6 0.1 1.4 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex Vps51 PF08700.11 OAG43354.1 - 0.037 14.1 0.6 2.9 8.0 0.0 3.2 3 0 0 3 3 3 0 Vps51/Vps67 cwf21 PF08312.12 OAG43356.1 - 8.3e-15 54.7 15.8 8.3e-15 54.7 15.8 1.9 2 0 0 2 2 2 1 cwf21 domain PSP PF04046.16 OAG43356.1 - 0.11 12.3 0.1 0.24 11.3 0.1 1.5 1 0 0 1 1 1 0 PSP DUF4407 PF14362.6 OAG43356.1 - 0.64 9.3 8.6 0.72 9.2 8.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) GFO_IDH_MocA PF01408.22 OAG43358.1 - 2.4e-18 67.1 0.1 4.2e-18 66.3 0.1 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Sugar_tr PF00083.24 OAG43359.1 - 3.8e-91 306.2 31.6 4.7e-91 305.9 31.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG43359.1 - 3.3e-21 75.6 60.5 2.3e-19 69.5 25.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 OAG43359.1 - 5.6e-10 38.1 2.6 5.6e-10 38.1 2.6 2.1 2 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family Epimerase PF01370.21 OAG43360.1 - 2.4e-10 40.3 0.2 2.6e-05 23.8 0.1 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 OAG43360.1 - 2.3e-06 27.6 0.1 4.3e-06 26.7 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 OAG43360.1 - 7.6e-06 26.4 0.0 1.6e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 OAG43360.1 - 0.0013 18.3 0.0 0.0092 15.4 0.0 2.1 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 OAG43360.1 - 0.006 16.2 0.0 0.0084 15.7 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.17 OAG43360.1 - 0.012 14.8 0.2 0.55 9.3 0.1 2.2 2 0 0 2 2 2 0 RmlD substrate binding domain 3Beta_HSD PF01073.19 OAG43360.1 - 0.028 13.4 0.0 0.15 11.1 0.0 1.9 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF3426 PF11906.8 OAG43360.1 - 0.13 12.4 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3426) DXP_reductoisom PF02670.16 OAG43360.1 - 0.16 12.7 0.0 0.35 11.6 0.0 1.6 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase adh_short_C2 PF13561.6 OAG43361.1 - 7.4e-61 205.7 3.9 8.6e-61 205.5 3.9 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG43361.1 - 1.3e-45 155.3 1.7 1.6e-45 155.0 1.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG43361.1 - 8.2e-09 35.6 2.1 1.2e-08 35.0 2.1 1.2 1 0 0 1 1 1 1 KR domain Transketolase_N PF00456.21 OAG43362.1 - 2.9e-102 342.1 0.1 4e-102 341.6 0.1 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 OAG43362.1 - 6.1e-34 117.2 0.1 1.4e-33 116.0 0.1 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 OAG43362.1 - 8.2e-10 38.6 0.0 2.1e-09 37.3 0.0 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 OAG43362.1 - 1.8e-06 27.4 0.0 0.0049 16.1 0.1 2.4 2 0 0 2 2 2 2 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.20 OAG43362.1 - 0.062 12.2 0.0 0.11 11.4 0.0 1.4 1 0 0 1 1 1 0 Dehydrogenase E1 component FMO-like PF00743.19 OAG43363.1 - 6.6e-14 51.2 0.0 1.6e-13 49.9 0.0 1.6 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 OAG43363.1 - 9.9e-10 38.1 0.0 3.4e-08 33.1 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG43363.1 - 9.6e-09 34.8 0.1 2.2e-07 30.4 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 OAG43363.1 - 1.4e-08 34.4 0.0 5.2e-08 32.5 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG43363.1 - 2.3e-07 30.9 0.0 7.4e-07 29.3 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAG43363.1 - 0.005 16.5 0.6 0.21 11.1 0.6 2.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase ADH_N PF08240.12 OAG43364.1 - 1.5e-28 98.8 0.9 2.8e-28 97.9 0.0 1.9 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG43364.1 - 2.9e-17 62.9 0.2 5.9e-17 61.9 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 OAG43364.1 - 2.3e-07 30.5 0.7 0.0042 16.6 0.1 2.5 2 1 0 2 2 2 2 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 OAG43364.1 - 1.4e-06 29.4 0.0 3.4e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Cas_csx3 PF09620.10 OAG43364.1 - 0.024 14.5 0.0 0.069 13.0 0.0 1.7 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_csx3) ThiF PF00899.21 OAG43364.1 - 0.046 13.1 0.6 0.1 11.9 0.6 1.5 1 0 0 1 1 1 0 ThiF family HI0933_like PF03486.14 OAG43364.1 - 0.059 12.1 1.4 0.084 11.6 1.4 1.2 1 0 0 1 1 1 0 HI0933-like protein UDPG_MGDP_dh_N PF03721.14 OAG43364.1 - 0.069 12.7 0.3 0.31 10.6 0.1 2.0 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain PALP PF00291.25 OAG43364.1 - 0.12 11.8 1.8 0.23 10.8 1.8 1.5 1 1 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme ADH_N PF08240.12 OAG43365.1 - 1.8e-27 95.4 0.1 3.9e-27 94.3 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG43365.1 - 1.1e-22 80.4 0.0 1.6e-22 79.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 OAG43365.1 - 3.3e-07 30.0 0.1 7.2e-07 28.9 0.1 1.6 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 OAG43365.1 - 9.2e-05 23.5 0.0 0.00018 22.5 0.0 1.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 OAG43365.1 - 0.057 12.8 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Zn_clus PF00172.18 OAG43366.1 - 4.6e-06 26.7 15.0 1.2e-05 25.4 15.0 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldo_ket_red PF00248.21 OAG43367.1 - 1.2e-40 139.6 0.0 4.2e-40 137.8 0.0 1.7 1 1 0 1 1 1 1 Aldo/keto reductase family Glyoxalase PF00903.25 OAG43368.1 - 1.7e-11 44.4 0.0 3.3e-11 43.5 0.0 1.5 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 OAG43368.1 - 8.3e-09 35.7 0.0 1e-08 35.4 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 OAG43368.1 - 3.5e-07 31.0 0.1 1.5e-06 29.0 0.1 1.8 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_3 PF13468.6 OAG43368.1 - 0.00016 21.9 0.1 0.0015 18.7 0.1 2.0 1 1 0 1 1 1 1 Glyoxalase-like domain Cyclase PF04199.13 OAG43369.1 - 7e-12 45.8 0.0 1e-11 45.2 0.0 1.3 1 0 0 1 1 1 1 Putative cyclase Aldedh PF00171.22 OAG43370.1 - 5.5e-166 552.7 0.2 6.3e-166 552.5 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family adh_short_C2 PF13561.6 OAG43371.1 - 1.3e-52 178.7 0.2 4.5e-52 176.9 0.1 1.9 2 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG43371.1 - 5.7e-43 146.7 0.1 1.3e-42 145.4 0.1 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG43371.1 - 1.3e-14 54.6 0.0 9.1e-14 51.8 0.0 2.1 2 0 0 2 2 2 1 KR domain Methyltransf_25 PF13649.6 OAG43371.1 - 0.014 16.1 0.0 0.029 15.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain HAUS4 PF14735.6 OAG43371.1 - 0.08 12.6 0.1 0.12 12.0 0.1 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 4 Sugar_tr PF00083.24 OAG43372.1 - 2.1e-94 317.0 22.9 2.5e-94 316.7 22.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG43372.1 - 4.8e-25 88.2 22.0 4.8e-25 88.2 22.0 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF2070 PF09843.9 OAG43372.1 - 0.59 8.3 7.0 1.2 7.3 7.0 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Glyco_transf_25 PF01755.17 OAG43374.1 - 0.0096 15.8 0.0 3.1 7.6 0.0 2.3 2 0 0 2 2 2 2 Glycosyltransferase family 25 (LPS biosynthesis protein) GAS2 PF02187.17 OAG43375.1 - 3.9e-06 26.9 0.1 8.4e-06 25.8 0.1 1.5 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain Pup PF05639.11 OAG43375.1 - 0.29 12.0 0.5 2.2 9.3 0.2 2.5 2 0 0 2 2 2 0 Pup-like protein MatP_C PF17414.2 OAG43375.1 - 1.3 9.3 3.0 4 7.7 0.1 3.2 4 0 0 4 4 4 0 MatP C-terminal ribbon-helix-helix domain Hus1 PF04005.12 OAG43376.1 - 2.4e-91 305.9 0.0 2.8e-91 305.7 0.0 1.0 1 0 0 1 1 1 1 Hus1-like protein Na_H_Exchanger PF00999.21 OAG43377.1 - 1.6e-71 241.2 40.2 1.9e-71 240.9 40.2 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family NiFe_hyd_3_EhaA PF17367.2 OAG43377.1 - 2.7 8.2 14.5 0.85 9.8 1.3 3.8 2 1 1 3 3 3 0 NiFe-hydrogenase-type-3 Eha complex subunit A SNF2_N PF00176.23 OAG43378.1 - 1.1e-71 241.4 0.9 1.1e-71 241.4 0.9 2.0 2 0 0 2 2 2 1 SNF2 family N-terminal domain Bromodomain PF00439.25 OAG43378.1 - 5.9e-22 77.5 0.3 1.6e-21 76.2 0.3 1.7 1 0 0 1 1 1 1 Bromodomain Helicase_C PF00271.31 OAG43378.1 - 2.8e-20 72.7 1.8 1.9e-18 66.8 0.0 3.8 3 1 1 4 4 4 1 Helicase conserved C-terminal domain HSA PF07529.13 OAG43378.1 - 3.7e-20 72.0 14.3 3.7e-20 72.0 14.3 4.8 4 1 1 5 5 5 1 HSA SnAC PF14619.6 OAG43378.1 - 5.3e-13 49.4 3.7 5.3e-13 49.4 3.7 4.2 4 1 1 5 5 5 1 Snf2-ATP coupling, chromatin remodelling complex ResIII PF04851.15 OAG43378.1 - 3.2e-11 43.5 0.0 3.2e-11 43.5 0.0 3.5 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit QLQ PF08880.11 OAG43378.1 - 3.1e-10 39.6 4.4 3.1e-10 39.6 4.4 2.8 2 0 0 2 2 2 1 QLQ BAR PF03114.18 OAG43379.1 - 1.5e-48 165.5 9.0 1.9e-48 165.2 9.0 1.1 1 0 0 1 1 1 1 BAR domain BAR_3 PF16746.5 OAG43379.1 - 4.2e-05 23.4 6.9 8.8e-05 22.3 6.9 1.5 1 1 0 1 1 1 1 BAR domain of APPL family BAR_2 PF10455.9 OAG43379.1 - 6.7e-05 22.2 4.7 9.4e-05 21.7 4.7 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking GBP_C PF02841.14 OAG43379.1 - 0.0052 16.2 7.5 0.0052 16.2 7.5 1.5 2 0 0 2 2 2 1 Guanylate-binding protein, C-terminal domain PMEI PF04043.15 OAG43379.1 - 0.0065 16.8 3.9 0.038 14.3 2.5 2.2 1 1 1 2 2 2 1 Plant invertase/pectin methylesterase inhibitor APG6_N PF17675.1 OAG43379.1 - 0.059 13.9 9.5 0.13 12.8 9.5 1.6 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF2018 PF09442.10 OAG43379.1 - 0.25 12.3 0.2 0.25 12.3 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF2018) ZapA PF05164.13 OAG43379.1 - 0.32 11.5 7.4 0.38 11.2 1.8 3.0 2 1 1 3 3 3 0 Cell division protein ZapA OmpH PF03938.14 OAG43379.1 - 1.1 9.6 13.6 3.7 7.9 9.9 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Strep_SA_rep PF06696.11 OAG43379.1 - 3.8 7.6 7.5 5.5 7.1 0.0 3.3 3 0 0 3 3 3 0 Streptococcal surface antigen repeat Ribosomal_L2_C PF03947.18 OAG43380.1 - 1.2e-41 141.8 4.8 2.5e-41 140.8 4.8 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 OAG43380.1 - 1.6e-12 47.2 0.0 5e-12 45.6 0.0 1.8 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain WHIM1 PF15612.6 OAG43381.1 - 3e-06 26.6 0.0 6.8e-06 25.5 0.0 1.6 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 Pkinase PF00069.25 OAG43382.1 - 5.9e-68 229.1 0.0 1.2e-67 228.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG43382.1 - 3.8e-50 170.6 0.0 9.5e-50 169.3 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Ras_bdg_2 PF14847.6 OAG43382.1 - 3.9e-29 100.9 0.0 8e-29 99.9 0.0 1.6 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_1 PF00536.30 OAG43382.1 - 5.4e-16 58.8 0.0 1.3e-15 57.6 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 OAG43382.1 - 3.7e-13 49.4 0.0 8e-13 48.3 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.23 OAG43382.1 - 1.2e-06 29.1 0.0 2.3e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Kinase-like PF14531.6 OAG43382.1 - 7.4e-05 22.2 0.0 0.028 13.7 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 OAG43382.1 - 0.0094 14.8 0.2 0.055 12.2 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase Seadorna_VP7 PF07387.11 OAG43382.1 - 0.08 12.0 0.0 0.27 10.3 0.0 1.8 2 0 0 2 2 2 0 Seadornavirus VP7 MSA-2c PF12238.8 OAG43382.1 - 0.14 12.1 2.8 0.2 11.6 0.0 2.3 2 0 0 2 2 2 0 Merozoite surface antigen 2c Kdo PF06293.14 OAG43382.1 - 0.14 11.5 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-C2H2 PF00096.26 OAG43383.1 - 0.038 14.4 0.6 0.038 14.4 0.6 4.0 4 0 0 4 4 4 0 Zinc finger, C2H2 type Lactamase_B PF00753.27 OAG43384.1 - 7.8e-07 29.3 1.4 6.2e-06 26.4 1.4 2.2 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OAG43384.1 - 0.00026 20.6 0.1 0.00041 19.9 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain FH2 PF02181.23 OAG43385.1 - 6.8e-84 282.1 5.8 6.8e-84 282.1 5.8 1.9 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.13 OAG43385.1 - 1.4e-63 213.9 0.1 3.8e-63 212.5 0.1 1.8 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 OAG43385.1 - 3.4e-51 173.6 1.0 3.4e-51 173.6 1.0 3.3 2 1 1 3 3 3 1 Diaphanous FH3 Domain Clp_N PF02861.20 OAG43385.1 - 1.1 9.5 3.5 24 5.1 0.7 2.7 2 0 0 2 2 2 0 Clp amino terminal domain, pathogenicity island component Sensor PF13796.6 OAG43386.1 - 0.013 15.6 0.5 0.025 14.6 0.5 1.5 1 0 0 1 1 1 0 Putative sensor STE PF02200.16 OAG43387.1 - 6.6e-56 187.4 0.0 1.2e-55 186.6 0.0 1.4 1 0 0 1 1 1 1 STE like transcription factor zf-C2H2 PF00096.26 OAG43387.1 - 1.3e-11 44.2 10.8 3.4e-07 30.3 0.9 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OAG43387.1 - 4.8e-09 36.2 3.5 4.8e-09 36.2 3.5 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 OAG43387.1 - 4.2e-08 33.4 8.7 0.00029 21.4 0.5 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 OAG43387.1 - 3.3e-05 23.8 0.4 3.3e-05 23.8 0.4 2.4 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OAG43387.1 - 0.0025 18.0 0.4 0.032 14.5 0.1 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding FYDLN_acid PF09538.10 OAG43387.1 - 0.01 16.5 1.1 0.026 15.2 1.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) zf-Di19 PF05605.12 OAG43387.1 - 0.042 14.1 2.6 0.087 13.1 2.6 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zinc_ribbon_9 PF14369.6 OAG43387.1 - 0.053 13.8 0.1 0.12 12.6 0.1 1.6 1 0 0 1 1 1 0 zinc-ribbon zf-BED PF02892.15 OAG43387.1 - 0.95 9.5 3.2 0.55 10.3 0.8 1.9 2 0 0 2 2 2 0 BED zinc finger DUF4602 PF15375.6 OAG43388.1 - 3.3e-15 56.6 7.3 8.3e-15 55.3 7.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4602) His_biosynth PF00977.21 OAG43389.1 - 1.2e-34 119.8 0.0 1.4e-34 119.5 0.0 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein Ribul_P_3_epim PF00834.19 OAG43389.1 - 0.13 11.7 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family Glyoxalase PF00903.25 OAG43391.1 - 3.3e-08 33.8 0.1 8.6e-08 32.4 0.1 1.6 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 OAG43391.1 - 0.00078 19.4 0.1 0.001 19.0 0.1 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Abhydrolase_1 PF00561.20 OAG43392.1 - 6.3e-26 91.6 0.0 9.7e-20 71.3 0.0 2.0 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG43392.1 - 2.2e-12 48.1 0.0 2.6e-12 47.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG43392.1 - 3.7e-08 32.9 0.0 0.00017 21.0 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 FSH1 PF03959.13 OAG43392.1 - 0.00011 21.9 0.0 0.0051 16.5 0.0 2.2 2 0 0 2 2 2 1 Serine hydrolase (FSH1) Chlorophyllase PF07224.11 OAG43392.1 - 0.076 12.0 0.0 0.83 8.6 0.0 2.1 2 0 0 2 2 2 0 Chlorophyllase Chlorophyllase2 PF12740.7 OAG43392.1 - 0.093 11.6 0.0 0.29 10.0 0.0 1.7 2 0 0 2 2 2 0 Chlorophyllase enzyme ECH_1 PF00378.20 OAG43393.1 - 2.3e-23 82.8 0.0 3.9e-23 82.0 0.0 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAG43393.1 - 3.7e-16 59.5 0.0 4.6e-16 59.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase UCH PF00443.29 OAG43393.1 - 0.11 12.0 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Abhydrolase_1 PF00561.20 OAG43394.1 - 5.1e-46 157.4 0.0 1.3e-45 156.1 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 OAG43394.1 - 0.00029 20.6 0.0 0.00053 19.7 0.0 1.4 1 0 0 1 1 1 1 Putative esterase ATP-synt_C PF00137.21 OAG43395.1 - 1.2e-27 96.0 37.1 7.1e-16 58.3 14.3 2.1 2 0 0 2 2 2 2 ATP synthase subunit C CNH PF00780.22 OAG43396.1 - 6.1e-78 262.2 0.0 3.5e-77 259.7 0.0 2.0 2 0 0 2 2 2 1 CNH domain PH_5 PF15405.6 OAG43396.1 - 8.8e-42 142.4 0.1 1.9e-41 141.3 0.1 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.20 OAG43396.1 - 1.7e-38 132.7 0.0 3.2e-38 131.8 0.0 1.5 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.21 OAG43396.1 - 2e-15 56.6 0.1 7.7e-14 51.5 0.0 2.4 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Brix PF04427.18 OAG43397.1 - 4.5e-24 85.6 0.0 6.5e-24 85.1 0.0 1.2 1 0 0 1 1 1 1 Brix domain TFIIA PF03153.13 OAG43397.1 - 0.27 11.2 6.3 0.41 10.6 6.3 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PRIMA1 PF16101.5 OAG43397.1 - 0.39 10.8 2.5 0.68 10.0 2.5 1.3 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 HGTP_anticodon PF03129.20 OAG43398.1 - 1.6e-22 79.5 0.0 1.6e-22 79.5 0.0 3.4 3 1 0 3 3 3 1 Anticodon binding domain tRNA-synt_2b PF00587.25 OAG43398.1 - 4.9e-08 33.2 0.0 2.2e-07 31.0 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) FAD_binding_3 PF01494.19 OAG43399.1 - 6.9e-51 173.5 0.0 8.9e-51 173.2 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAG43399.1 - 6.2e-10 39.2 1.0 0.00012 21.8 0.4 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 OAG43399.1 - 6.6e-06 26.6 0.1 0.0025 18.3 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAG43399.1 - 1.2e-05 24.7 0.1 0.00083 18.7 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAG43399.1 - 0.0001 21.5 0.2 0.0056 15.8 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain ApbA PF02558.16 OAG43399.1 - 0.00028 20.5 0.2 0.0005 19.7 0.2 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_8 PF13450.6 OAG43399.1 - 0.00037 20.7 0.2 0.00086 19.5 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 OAG43399.1 - 0.0033 16.2 0.1 0.0084 14.9 0.1 1.6 2 0 0 2 2 2 1 HI0933-like protein Lycopene_cycl PF05834.12 OAG43399.1 - 0.0038 16.3 0.2 0.11 11.6 0.2 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 OAG43399.1 - 0.023 14.0 0.0 0.19 11.0 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 OAG43399.1 - 0.031 14.7 0.2 0.08 13.4 0.0 1.7 2 0 0 2 2 2 0 Putative NAD(P)-binding GIDA PF01134.22 OAG43399.1 - 0.048 12.7 0.3 0.066 12.3 0.3 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_oxidored PF12831.7 OAG43399.1 - 0.079 12.3 0.0 2 7.6 0.3 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase ThiF PF00899.21 OAG43399.1 - 0.27 10.6 1.1 0.57 9.5 0.8 1.6 2 0 0 2 2 2 0 ThiF family DUF410 PF04190.13 OAG43401.1 - 3.1e-84 282.8 0.0 3.8e-84 282.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF410) TPR_20 PF14561.6 OAG43401.1 - 0.073 13.4 0.0 0.51 10.7 0.0 2.3 2 1 0 2 2 2 0 Tetratricopeptide repeat Response_reg PF00072.24 OAG43402.1 - 6.8e-20 71.3 0.0 5.7e-14 52.2 0.0 2.3 2 0 0 2 2 2 2 Response regulator receiver domain RRM_1 PF00076.22 OAG43403.1 - 2.2e-16 59.4 0.0 1.4e-13 50.4 0.0 2.7 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OAG43403.1 - 0.067 13.1 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 Occluded RNA-recognition motif Tup_N PF08581.10 OAG43404.1 - 0.64 10.4 5.4 38 4.7 0.0 3.6 3 0 0 3 3 3 0 Tup N-terminal Prominin PF05478.11 OAG43404.1 - 0.82 7.6 3.5 1.2 7.0 3.5 1.2 1 0 0 1 1 1 0 Prominin Pkinase PF00069.25 OAG43405.1 - 1.7e-60 204.6 0.0 2.3e-60 204.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG43405.1 - 1.1e-27 97.0 0.0 6.1e-19 68.3 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 OAG43405.1 - 0.034 13.5 0.4 2.8 7.2 0.0 2.6 3 0 0 3 3 3 0 Kinase-like Haspin_kinase PF12330.8 OAG43405.1 - 0.045 12.7 0.0 0.061 12.3 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Choline_kinase PF01633.20 OAG43405.1 - 0.15 11.6 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Gly_transf_sug PF04488.15 OAG43406.1 - 1.9e-14 54.1 0.0 7.3e-14 52.2 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif VASt PF16016.5 OAG43407.1 - 2.6e-37 128.6 0.0 6.1e-37 127.4 0.0 1.6 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 OAG43407.1 - 4.7e-22 78.0 0.0 1.1e-21 76.8 0.0 1.7 1 0 0 1 1 1 1 GRAM domain Phage_min_cap2 PF06152.11 OAG43407.1 - 0.98 8.3 5.5 1.8 7.4 5.5 1.4 1 0 0 1 1 1 0 Phage minor capsid protein 2 MPS2 PF17060.5 OAG43408.1 - 0.035 13.4 0.0 0.051 12.8 0.0 1.3 1 0 0 1 1 1 0 Monopolar spindle protein 2 Mg_trans_NIPA PF05653.14 OAG43409.1 - 5.2e-66 222.7 6.8 2.6e-65 220.4 3.2 2.0 2 0 0 2 2 2 1 Magnesium transporter NIPA EamA PF00892.20 OAG43409.1 - 0.0022 18.2 0.4 0.0022 18.2 0.4 4.0 3 1 1 4 4 4 1 EamA-like transporter family SLC35F PF06027.12 OAG43409.1 - 0.0071 15.9 6.5 0.083 12.4 0.0 2.3 2 0 0 2 2 2 1 Solute carrier family 35 Tetraspanin PF00335.20 OAG43409.1 - 0.052 13.3 0.4 41 3.8 0.0 3.4 3 0 0 3 3 3 0 Tetraspanin family DUF872 PF05915.12 OAG43409.1 - 0.61 10.3 4.7 2 8.6 0.2 2.7 2 1 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) TssN PF17555.2 OAG43409.1 - 0.75 9.1 10.0 1.2 8.5 10.0 1.2 1 0 0 1 1 1 0 Type VI secretion system, TssN DUF1211 PF06736.11 OAG43409.1 - 0.94 10.0 4.0 1.2 9.6 2.0 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1211) Trp_oprn_chp PF09534.10 OAG43409.1 - 0.95 9.2 4.9 5.5 6.7 2.4 3.0 3 1 0 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) BaxI_1 PF12811.7 OAG43409.1 - 1.2 8.6 9.3 1.5 8.3 7.7 2.0 2 1 0 2 2 2 0 Bax inhibitor 1 like RAMP4 PF06624.12 OAG43409.1 - 1.4 9.1 5.3 0.4 10.8 0.6 2.5 3 0 0 3 3 3 0 Ribosome associated membrane protein RAMP4 DUF3431 PF11913.8 OAG43411.1 - 1.6e-78 263.4 0.5 1.9e-78 263.1 0.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Glyco_hydro_47 PF01532.20 OAG43412.1 - 5e-153 510.3 0.0 5.6e-153 510.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 RRM_1 PF00076.22 OAG43413.1 - 7.9e-18 64.0 0.0 1.2e-17 63.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 OAG43413.1 - 5.6e-07 30.0 7.0 5.6e-07 30.0 7.0 3.4 2 1 1 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 Abhydrolase_3 PF07859.13 OAG43414.1 - 1.3e-41 142.8 0.0 1.7e-41 142.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold WD40 PF00400.32 OAG43415.1 - 2.9e-11 43.7 18.3 0.0029 18.4 0.2 6.2 7 0 0 7 7 7 3 WD domain, G-beta repeat MraZ PF02381.18 OAG43415.1 - 0.11 12.5 0.0 8.3 6.5 0.0 2.4 2 0 0 2 2 2 0 MraZ protein, putative antitoxin-like MIP PF00230.20 OAG43416.1 - 6.7e-54 183.0 3.8 8.5e-54 182.7 3.8 1.1 1 0 0 1 1 1 1 Major intrinsic protein OsmC PF02566.19 OAG43417.1 - 1.2e-18 67.5 0.0 2e-18 66.7 0.0 1.3 1 0 0 1 1 1 1 OsmC-like protein C2-set_2 PF08205.12 OAG43417.1 - 0.082 13.0 0.2 0.14 12.2 0.2 1.4 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain CVNH PF08881.10 OAG43418.1 - 1.3e-27 96.5 0.8 2.1e-27 95.7 0.8 1.4 1 0 0 1 1 1 1 CVNH domain Rick_17kDa_Anti PF05433.15 OAG43418.1 - 2.6e-05 24.0 12.7 2.6e-05 24.0 12.7 2.2 2 0 0 2 2 2 1 Glycine zipper 2TM domain TraT PF05818.12 OAG43418.1 - 0.00092 19.0 5.0 0.0045 16.7 0.7 2.2 2 0 0 2 2 2 1 Enterobacterial TraT complement resistance protein Gly-zipper_Omp PF13488.6 OAG43418.1 - 0.0012 18.8 7.6 0.0012 18.8 7.6 2.3 2 0 0 2 2 2 1 Glycine zipper TctA PF01970.16 OAG43418.1 - 0.19 10.4 0.5 0.29 9.8 0.5 1.2 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctA family DUF533 PF04391.12 OAG43418.1 - 0.38 10.3 12.2 0.1 12.2 1.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF533) MRI PF15325.6 OAG43418.1 - 0.62 11.2 5.3 2.2 9.4 5.3 1.9 1 0 0 1 1 1 0 Modulator of retrovirus infection Dehydrin PF00257.19 OAG43418.1 - 2.1 8.9 22.1 0.067 13.7 10.7 2.7 1 1 1 2 2 2 0 Dehydrin Macoilin PF09726.9 OAG43418.1 - 2.5 6.5 4.9 3.2 6.2 4.9 1.1 1 0 0 1 1 1 0 Macoilin family SR-25 PF10500.9 OAG43418.1 - 2.9 7.5 25.4 0.2 11.2 20.1 1.6 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein CCDC106 PF15794.5 OAG43418.1 - 3.6 7.2 7.3 5.6 6.6 7.3 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 ABA_WDS PF02496.16 OAG43418.1 - 3.8 8.1 15.5 1.8 9.1 0.9 3.2 2 1 0 2 2 2 0 ABA/WDS induced protein NAD_kinase PF01513.21 OAG43420.1 - 5.8e-51 173.4 0.0 8.3e-51 172.9 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 OAG43420.1 - 0.0014 18.2 0.0 0.0028 17.3 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain YppF PF14178.6 OAG43420.1 - 0.13 12.2 0.1 5.2 7.0 0.0 2.4 2 0 0 2 2 2 0 YppF-like protein Acyltransferase PF01553.21 OAG43421.1 - 1.6e-25 89.2 0.0 2.6e-25 88.6 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 OAG43421.1 - 2.3e-13 50.0 0.0 4.9e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase C-terminus Sulfotransfer_4 PF17784.1 OAG43422.1 - 2.7e-47 161.4 0.6 3.2e-47 161.2 0.6 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OAG43422.1 - 5.5e-05 23.7 0.2 0.004 17.6 0.2 2.1 1 1 0 1 1 1 1 Sulfotransferase family Sod_Cu PF00080.20 OAG43424.1 - 1.1e-47 161.7 6.6 1.3e-47 161.5 6.6 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) CRAL_TRIO PF00650.20 OAG43425.1 - 4e-21 75.4 0.0 6.3e-21 74.7 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 OAG43425.1 - 3.8e-10 39.8 0.0 1.2e-09 38.2 0.0 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain P5-ATPase PF12409.8 OAG43426.1 - 2e-37 128.1 0.1 4.4e-37 127.0 0.1 1.6 1 0 0 1 1 1 1 P5-type ATPase cation transporter E1-E2_ATPase PF00122.20 OAG43426.1 - 3.4e-28 98.4 0.0 8.4e-28 97.1 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 OAG43426.1 - 1.3e-14 55.0 0.4 6.8e-06 26.5 0.0 3.3 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 OAG43426.1 - 3.2e-05 23.9 0.0 8e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_C PF00689.21 OAG43426.1 - 8.1e-05 22.4 6.3 8.1e-05 22.4 6.3 2.5 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase_N PF00690.26 OAG43426.1 - 0.0028 17.3 0.1 0.0088 15.7 0.0 1.9 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 OAG43426.1 - 0.05 13.3 0.0 6.2 6.5 0.0 2.3 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase NAP PF00956.18 OAG43427.1 - 4.2e-100 334.4 5.8 4.2e-100 334.4 5.8 1.8 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) RNA_pol_3_Rpc31 PF11705.8 OAG43427.1 - 1.3 9.2 25.9 0.34 11.1 14.8 2.5 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Myosin_head PF00063.21 OAG43428.1 - 4e-262 871.3 1.8 5.7e-262 870.9 1.8 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) DIL PF01843.19 OAG43428.1 - 3.2e-26 91.6 2.6 3.2e-26 91.6 2.6 2.5 2 0 0 2 2 1 1 DIL domain IQ PF00612.27 OAG43428.1 - 2.8e-12 45.3 31.1 0.0014 18.3 0.1 6.8 7 0 0 7 7 6 4 IQ calmodulin-binding motif GAS PF13851.6 OAG43428.1 - 0.00017 21.0 26.3 0.0082 15.5 13.1 2.9 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding AAA_16 PF13191.6 OAG43428.1 - 0.0035 17.8 0.5 0.012 16.0 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain PhoH PF02562.16 OAG43428.1 - 0.061 12.8 0.3 6.5 6.1 0.1 3.9 4 1 0 4 4 4 0 PhoH-like protein AAA_22 PF13401.6 OAG43428.1 - 0.086 13.1 3.2 0.089 13.1 0.1 2.5 2 1 0 2 2 2 0 AAA domain Spc7 PF08317.11 OAG43428.1 - 0.1 11.5 24.5 0.13 11.1 10.6 2.5 1 1 1 2 2 2 0 Spc7 kinetochore protein NACHT PF05729.12 OAG43428.1 - 0.11 12.5 0.1 0.36 10.7 0.1 1.9 1 0 0 1 1 1 0 NACHT domain KASH_CCD PF14662.6 OAG43428.1 - 0.12 12.1 26.5 0.019 14.8 8.0 3.0 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH RNA_helicase PF00910.22 OAG43428.1 - 0.13 12.7 0.0 3.1 8.2 0.0 2.9 2 0 0 2 2 2 0 RNA helicase Phage_GP20 PF06810.11 OAG43428.1 - 0.14 11.9 10.5 1.5 8.6 0.9 2.9 1 1 1 2 2 2 0 Phage minor structural protein GP20 ATG16 PF08614.11 OAG43428.1 - 0.28 11.4 29.1 13 5.9 18.7 2.9 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Prefoldin PF02996.17 OAG43428.1 - 0.32 10.9 8.2 3.6 7.5 1.0 3.4 2 1 0 2 2 2 0 Prefoldin subunit Cep57_CLD PF14073.6 OAG43428.1 - 0.43 10.6 23.1 1.1 9.2 23.1 1.7 1 0 0 1 1 1 0 Centrosome localisation domain of Cep57 DegQ PF08181.11 OAG43428.1 - 0.46 10.6 8.7 0.063 13.4 2.0 3.1 3 0 0 3 3 2 0 DegQ (SacQ) family DUF4665 PF15679.5 OAG43428.1 - 0.87 10.2 3.9 0.68 10.6 0.9 2.4 2 0 0 2 2 1 0 Domain of unknown function (DUF4665) ABC_tran PF00005.27 OAG43428.1 - 0.93 10.0 0.0 0.93 10.0 0.0 3.1 2 1 0 2 2 1 0 ABC transporter DUF4201 PF13870.6 OAG43428.1 - 3 7.6 22.0 22 4.7 7.5 3.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) FlaC_arch PF05377.11 OAG43428.1 - 4 7.9 16.2 4.1 7.9 0.7 4.4 4 0 0 4 4 3 0 Flagella accessory protein C (FlaC) Snapin_Pallidin PF14712.6 OAG43428.1 - 4.4 7.8 19.5 1.5 9.3 6.6 4.3 3 1 1 4 4 4 0 Snapin/Pallidin FUSC PF04632.12 OAG43428.1 - 6.9 5.1 7.8 13 4.1 7.8 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family Fungal_trans_2 PF11951.8 OAG43429.1 - 0.00071 18.5 0.0 0.0012 17.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain HpcH_HpaI PF03328.14 OAG43431.1 - 4.6e-33 114.2 0.0 5.8e-33 113.9 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family TauD PF02668.16 OAG43432.1 - 4.5e-55 187.3 1.2 5.2e-55 187.1 1.2 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Fungal_trans PF04082.18 OAG43433.1 - 8.3e-15 54.5 1.9 9.6e-15 54.3 0.6 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG43433.1 - 3.7e-07 30.2 8.3 1.1e-06 28.6 8.3 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AAA_18 PF13238.6 OAG43434.1 - 9.4e-24 84.4 0.1 1.9e-23 83.4 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 OAG43434.1 - 3.7e-09 37.1 0.0 1.9e-08 34.8 0.0 2.0 1 1 1 2 2 2 1 AAA domain AAA_22 PF13401.6 OAG43434.1 - 0.00067 19.9 0.0 0.0012 19.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 OAG43434.1 - 0.00077 19.4 1.0 0.002 18.0 0.3 1.9 2 0 0 2 2 2 1 NTPase AAA PF00004.29 OAG43434.1 - 0.0015 19.0 0.0 0.0025 18.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OAG43434.1 - 0.0057 17.0 0.1 0.012 16.0 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.22 OAG43434.1 - 0.0064 16.9 0.0 0.012 16.0 0.0 1.4 1 0 0 1 1 1 1 RNA helicase AAA_28 PF13521.6 OAG43434.1 - 0.0069 16.6 2.1 0.011 16.0 0.8 1.8 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 OAG43434.1 - 0.012 15.3 0.0 0.017 14.9 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_5 PF07728.14 OAG43434.1 - 0.013 15.5 0.0 0.024 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) FtsK_SpoIIIE PF01580.18 OAG43434.1 - 0.014 14.8 0.5 0.014 14.8 0.5 1.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_14 PF13173.6 OAG43434.1 - 0.016 15.3 0.0 0.031 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 OAG43434.1 - 0.02 14.6 1.7 0.043 13.5 0.7 2.1 1 1 1 2 2 2 0 AAA domain KTI12 PF08433.10 OAG43434.1 - 0.026 14.0 0.0 0.038 13.5 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 DAP3 PF10236.9 OAG43434.1 - 0.036 13.2 0.0 0.051 12.7 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_25 PF13481.6 OAG43434.1 - 0.036 13.6 0.8 0.53 9.8 0.1 2.3 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 OAG43434.1 - 0.041 13.5 0.1 0.074 12.7 0.1 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ATP_bind_1 PF03029.17 OAG43434.1 - 0.043 13.6 0.1 0.065 13.0 0.1 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein NACHT PF05729.12 OAG43434.1 - 0.049 13.6 0.0 0.15 11.9 0.0 1.8 2 0 0 2 2 2 0 NACHT domain AAA_19 PF13245.6 OAG43434.1 - 0.053 13.9 1.2 0.082 13.2 0.8 1.5 1 1 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.9 OAG43434.1 - 0.057 12.3 0.1 0.088 11.7 0.1 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain T2SSE PF00437.20 OAG43434.1 - 0.062 12.4 0.1 0.11 11.6 0.1 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein Mg_chelatase PF01078.21 OAG43434.1 - 0.091 12.1 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Microtub_bd PF16796.5 OAG43434.1 - 0.15 12.0 0.0 1.4 8.9 0.0 2.0 2 0 0 2 2 2 0 Microtubule binding CbiA PF01656.23 OAG43434.1 - 0.16 12.0 1.1 0.34 11.0 0.8 1.7 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain ADK PF00406.22 OAG43434.1 - 0.18 11.9 0.7 0.6 10.2 0.7 2.0 1 1 0 1 1 1 0 Adenylate kinase COPI_C PF06957.11 OAG43434.1 - 2.6 6.7 4.7 3.1 6.4 1.0 2.0 2 0 0 2 2 2 0 Coatomer (COPI) alpha subunit C-terminus Ham1p_like PF01725.16 OAG43435.1 - 1.3e-55 188.2 0.0 1.5e-55 188.0 0.0 1.0 1 0 0 1 1 1 1 Ham1 family Peptidase_C78 PF07910.13 OAG43436.1 - 7.4e-64 215.1 0.0 9.8e-64 214.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C78 zf-Di19 PF05605.12 OAG43436.1 - 0.0018 18.5 0.6 0.0018 18.5 0.6 1.8 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf_C2H2_ZHX PF18387.1 OAG43436.1 - 0.11 12.1 0.1 0.33 10.6 0.1 1.7 1 0 0 1 1 1 0 Zinc-fingers and homeoboxes C2H2 finger domain AA_kinase PF00696.28 OAG43437.1 - 5.3e-43 147.3 0.1 8.2e-43 146.7 0.1 1.3 1 0 0 1 1 1 1 Amino acid kinase family ACT_7 PF13840.6 OAG43437.1 - 3.7e-11 42.7 1.8 5.7e-10 38.8 0.3 2.4 2 0 0 2 2 2 1 ACT domain ACT PF01842.25 OAG43437.1 - 4e-07 29.7 0.1 3.2e-06 26.8 0.1 2.3 2 0 0 2 2 2 1 ACT domain Forkhead PF00250.18 OAG43438.1 - 5.1e-34 116.4 0.2 9.2e-34 115.6 0.2 1.4 1 0 0 1 1 1 1 Forkhead domain Dyp_perox PF04261.12 OAG43439.1 - 8.4e-89 297.8 0.0 9.6e-89 297.6 0.0 1.0 1 0 0 1 1 1 1 Dyp-type peroxidase family Ribosomal_S10 PF00338.22 OAG43440.1 - 8.8e-27 93.2 0.0 2.1e-26 92.0 0.0 1.7 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e GMC_oxred_N PF00732.19 OAG43441.1 - 1.7e-26 93.3 0.0 1.9e-26 93.1 0.0 1.0 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 OAG43441.1 - 0.00022 20.4 0.0 0.00026 20.2 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 OAG43441.1 - 0.00044 19.4 0.1 0.0005 19.2 0.1 1.1 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 OAG43441.1 - 0.0014 18.8 0.2 0.0043 17.3 0.3 1.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAG43441.1 - 0.0062 15.8 0.1 0.0078 15.5 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAG43441.1 - 0.01 14.6 0.0 0.012 14.3 0.0 1.1 1 0 0 1 1 1 0 HI0933-like protein TrkA_N PF02254.18 OAG43441.1 - 0.019 15.2 0.1 0.025 14.8 0.1 1.2 1 0 0 1 1 1 0 TrkA-N domain DAO PF01266.24 OAG43441.1 - 0.022 14.4 2.8 0.043 13.4 2.8 1.7 1 1 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 OAG43441.1 - 0.11 13.1 0.0 0.14 12.7 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GDI PF00996.18 OAG43441.1 - 0.11 11.0 0.0 0.13 10.8 0.0 1.1 1 0 0 1 1 1 0 GDP dissociation inhibitor FAD_oxidored PF12831.7 OAG43441.1 - 0.17 11.2 0.8 0.27 10.5 0.8 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Trp_halogenase PF04820.14 OAG43441.1 - 0.2 10.4 0.1 0.26 10.1 0.1 1.1 1 0 0 1 1 1 0 Tryptophan halogenase GMC_oxred_C PF05199.13 OAG43442.1 - 2.3e-37 128.7 0.0 3.7e-37 128.0 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 OAG43442.1 - 9.3e-30 104.0 0.0 2e-29 102.9 0.0 1.5 2 0 0 2 2 2 1 GMC oxidoreductase tRNA-synt_1b PF00579.25 OAG43443.1 - 1e-64 218.7 0.0 1.5e-64 218.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) DinB_2 PF12867.7 OAG43443.1 - 0.056 14.0 0.0 0.18 12.3 0.0 1.9 1 0 0 1 1 1 0 DinB superfamily Abhydrolase_1 PF00561.20 OAG43444.1 - 7.4e-25 88.1 0.0 6.5e-24 85.0 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG43444.1 - 1.5e-14 55.2 3.0 3e-14 54.2 3.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG43444.1 - 1.7e-10 40.6 0.0 2.4e-10 40.1 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 OAG43444.1 - 2.3e-07 31.2 0.0 3.9e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain Esterase PF00756.20 OAG43444.1 - 0.00017 21.4 0.0 0.00023 20.9 0.0 1.3 1 0 0 1 1 1 1 Putative esterase PGAP1 PF07819.13 OAG43444.1 - 0.0027 17.5 0.2 0.43 10.3 0.1 2.1 1 1 1 2 2 2 2 PGAP1-like protein Lipase_3 PF01764.25 OAG43444.1 - 0.028 14.3 0.0 0.045 13.6 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Chlorophyllase2 PF12740.7 OAG43444.1 - 0.028 13.3 0.0 0.042 12.7 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Ribosomal_S3Ae PF01015.18 OAG43445.1 - 1.5e-89 298.9 2.8 1.8e-89 298.7 2.8 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family SUI1 PF01253.22 OAG43445.1 - 0.008 16.7 0.3 0.081 13.5 0.0 2.3 2 0 0 2 2 2 1 Translation initiation factor SUI1 Ribosomal_L22 PF00237.19 OAG43445.1 - 0.1 12.9 0.2 0.18 12.0 0.2 1.4 1 0 0 1 1 1 0 Ribosomal protein L22p/L17e Abhydro_lipase PF04083.16 OAG43445.1 - 0.18 11.4 0.0 0.36 10.4 0.0 1.5 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region tRNA-synt_2b PF00587.25 OAG43446.1 - 4.8e-30 104.9 0.0 8.3e-30 104.1 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 OAG43446.1 - 3.8e-14 52.8 5.2 3.8e-14 52.8 5.2 2.0 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain DUF5082 PF16888.5 OAG43446.1 - 0.044 14.1 3.2 0.096 13.0 3.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) DUF4088 PF13317.6 OAG43446.1 - 0.066 12.8 0.4 0.11 12.1 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4088) Cytochrom_C552 PF02335.15 OAG43446.1 - 0.15 10.9 4.3 0.17 10.8 0.0 2.1 2 0 0 2 2 2 0 Cytochrome c552 Nup192 PF11894.8 OAG43446.1 - 0.48 7.5 1.7 0.64 7.1 1.7 1.1 1 0 0 1 1 1 0 Nuclear pore complex scaffold, nucleoporins 186/192/205 Ras PF00071.22 OAG43447.1 - 1.2e-47 161.5 0.2 1.4e-47 161.3 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAG43447.1 - 3e-15 56.5 0.0 4.6e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAG43447.1 - 2.3e-08 33.7 0.0 2.5e-08 33.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OAG43447.1 - 1.4e-05 24.7 0.2 8.1e-05 22.2 0.1 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 OAG43447.1 - 0.00012 21.6 0.1 0.00021 20.8 0.1 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 OAG43447.1 - 0.00017 21.5 0.1 0.035 14.0 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 OAG43447.1 - 0.00051 19.6 0.1 0.0048 16.4 0.1 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1 PF01926.23 OAG43447.1 - 0.0013 18.8 0.0 0.0019 18.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase zf_ZIC PF18366.1 OAG43447.1 - 0.047 13.8 0.0 0.24 11.5 0.0 2.2 2 0 0 2 2 2 0 Zic proteins zinc finger domain AAA_14 PF13173.6 OAG43447.1 - 0.074 13.1 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain WAPL PF07814.13 OAG43448.1 - 2.7e-34 118.5 5.4 1e-33 116.7 5.4 1.9 1 1 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin UPRTase PF14681.6 OAG43449.1 - 3.7e-80 268.2 0.0 4.6e-80 267.9 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 OAG43449.1 - 0.00074 19.1 0.0 0.0011 18.5 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain 2-Hacid_dh_C PF02826.19 OAG43450.1 - 3e-52 176.6 0.0 4.8e-52 175.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 OAG43450.1 - 2.7e-37 127.4 0.0 3.9e-37 126.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 OAG43450.1 - 0.00026 21.2 0.1 0.00073 19.7 0.1 1.8 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ACT PF01842.25 OAG43450.1 - 0.00029 20.5 0.1 0.00064 19.4 0.1 1.6 1 0 0 1 1 1 1 ACT domain IlvN PF07991.12 OAG43450.1 - 0.1 12.2 0.1 0.32 10.6 0.0 1.9 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain XdhC_C PF13478.6 OAG43450.1 - 0.11 13.0 0.1 0.43 11.1 0.0 2.0 3 0 0 3 3 3 0 XdhC Rossmann domain DUF1780 PF08682.10 OAG43450.1 - 0.16 11.6 0.0 0.29 10.8 0.0 1.3 1 0 0 1 1 1 0 Putative endonuclease, protein of unknown function (DUF1780) PD40 PF07676.12 OAG43451.1 - 0.15 12.0 0.1 1.3 9.1 0.0 2.3 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Ribosomal_L19e PF01280.20 OAG43452.1 - 1.1e-61 207.1 7.8 1.1e-61 207.1 7.8 1.8 2 0 0 2 2 2 1 Ribosomal protein L19e TRAP-gamma PF07074.12 OAG43452.1 - 1.4 8.4 4.9 2 7.9 4.9 1.2 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) KilA-N PF04383.13 OAG43453.1 - 0.00031 20.6 0.0 0.0042 16.9 0.0 2.1 1 1 0 1 1 1 1 KilA-N domain Elf1 PF05129.13 OAG43454.1 - 5.6e-30 103.2 0.7 7e-30 102.9 0.7 1.1 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like EST1_DNA_bind PF10373.9 OAG43454.1 - 0.011 15.3 0.0 0.016 14.7 0.0 1.3 1 1 0 1 1 1 0 Est1 DNA/RNA binding domain zf-Sec23_Sec24 PF04810.15 OAG43454.1 - 0.62 10.2 4.0 3.3 7.8 0.6 2.2 1 1 1 2 2 2 0 Sec23/Sec24 zinc finger GTP_CH_N PF12471.8 OAG43455.1 - 3.5e-92 307.5 0.0 5.5e-92 306.8 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.20 OAG43455.1 - 3.2e-17 62.6 0.0 5.3e-17 61.9 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase II SHMT PF00464.19 OAG43457.1 - 6.8e-199 660.5 0.0 7.9e-199 660.2 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase AMP-binding PF00501.28 OAG43459.1 - 3e-75 253.4 0.0 3.6e-75 253.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 OAG43459.1 - 1.8e-18 66.2 1.2 7.7e-18 64.2 0.3 2.4 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 OAG43459.1 - 4.8e-16 59.5 0.0 1.6e-15 57.8 0.0 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AdoMet_MTase PF07757.13 OAG43460.1 - 8.2e-35 119.5 0.0 1.5e-34 118.7 0.0 1.3 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_32 PF13679.6 OAG43460.1 - 0.041 13.9 0.0 0.94 9.5 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain Sec34 PF04136.15 OAG43461.1 - 2.1e-47 160.8 3.2 2.1e-47 160.8 3.2 1.9 2 0 0 2 2 2 1 Sec34-like family ALIX_LYPXL_bnd PF13949.6 OAG43461.1 - 0.016 14.5 7.2 0.11 11.8 4.2 2.4 2 0 0 2 2 2 0 ALIX V-shaped domain binding to HIV Bep_C_terminal PF17841.1 OAG43461.1 - 0.019 15.2 1.9 5.5 7.3 0.0 3.3 3 0 0 3 3 3 0 BID domain of Bartonella effector protein (Bep) CorA PF01544.18 OAG43461.1 - 0.52 9.6 2.8 1.3 8.3 2.6 1.7 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein Apolipoprotein PF01442.18 OAG43461.1 - 1.4 8.8 13.6 0.088 12.7 0.5 2.8 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain DUF883 PF05957.13 OAG43461.1 - 7.3 7.3 7.5 7.7 7.2 0.3 3.3 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) RCC1 PF00415.18 OAG43462.1 - 1.8e-27 95.7 5.5 4.6e-07 30.3 0.0 7.6 6 1 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OAG43462.1 - 2.3e-13 49.5 25.8 8.5e-09 35.0 0.0 7.4 8 0 0 8 8 8 4 Regulator of chromosome condensation (RCC1) repeat RskA PF10099.9 OAG43462.1 - 0.052 13.8 3.7 0.089 13.1 3.7 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA ASF1_hist_chap PF04729.13 OAG43463.1 - 1.3e-72 242.8 0.0 2.1e-72 242.1 0.0 1.3 1 0 0 1 1 1 1 ASF1 like histone chaperone Nop14 PF04147.12 OAG43463.1 - 0.0057 14.9 32.8 0.0076 14.5 32.8 1.0 1 0 0 1 1 1 1 Nop14-like family Efg1 PF10153.9 OAG43463.1 - 0.3 11.5 4.1 0.57 10.6 4.1 1.4 1 0 0 1 1 1 0 rRNA-processing protein Efg1 Nop53 PF07767.11 OAG43463.1 - 0.38 10.1 22.0 0.48 9.8 22.0 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Suf PF05843.14 OAG43464.1 - 9.5e-79 265.5 8.5 1.2e-78 265.1 0.0 3.7 4 0 0 4 4 4 1 Suppressor of forked protein (Suf) TPR_14 PF13428.6 OAG43464.1 - 4e-05 24.1 1.0 0.061 14.2 0.0 4.1 3 1 1 4 4 4 2 Tetratricopeptide repeat SUIM_assoc PF16619.5 OAG43464.1 - 0.39 10.8 4.9 0.41 10.8 2.1 2.4 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Piwi PF02171.17 OAG43465.1 - 9.7e-70 235.2 0.3 1.5e-69 234.5 0.3 1.2 1 0 0 1 1 1 1 Piwi domain ArgoL1 PF08699.10 OAG43465.1 - 1.4e-19 69.5 0.0 2.9e-19 68.5 0.0 1.6 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoN PF16486.5 OAG43465.1 - 5.4e-17 62.7 0.2 2.1e-16 60.8 0.0 2.1 2 0 0 2 2 2 1 N-terminal domain of argonaute PAZ PF02170.22 OAG43465.1 - 6.4e-15 55.2 0.1 1.3e-14 54.2 0.1 1.5 1 0 0 1 1 1 1 PAZ domain ArgoL2 PF16488.5 OAG43465.1 - 3.3e-11 43.3 0.0 8.2e-11 42.1 0.0 1.7 1 0 0 1 1 1 1 Argonaute linker 2 domain ArgoMid PF16487.5 OAG43465.1 - 3.2e-05 24.1 0.0 8.6e-05 22.7 0.0 1.8 1 0 0 1 1 1 1 Mid domain of argonaute DUF5569 PF17729.1 OAG43465.1 - 0.058 13.3 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5569) Ca_hom_mod PF14798.6 OAG43466.1 - 0.028 13.5 0.2 0.043 12.9 0.2 1.3 1 0 0 1 1 1 0 Calcium homeostasis modulator p450 PF00067.22 OAG43468.1 - 5.2e-56 190.3 0.0 6.9e-56 189.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_7 PF03441.14 OAG43469.1 - 2.1e-46 157.9 0.1 3.6e-46 157.2 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 OAG43469.1 - 7.5e-20 71.6 0.0 1.8e-19 70.3 0.0 1.6 1 0 0 1 1 1 1 DNA photolyase zf-C2H2 PF00096.26 OAG43470.1 - 5.2e-12 45.5 10.9 4.3e-06 26.9 0.6 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAG43470.1 - 3.6e-09 36.7 8.9 0.00034 21.2 0.6 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OAG43470.1 - 5.1e-07 29.8 11.0 1.9e-05 24.9 2.3 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-H2C2_5 PF13909.6 OAG43470.1 - 3.6e-05 23.4 7.4 0.0065 16.2 0.2 2.6 2 0 0 2 2 2 2 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 OAG43470.1 - 0.00064 19.9 4.1 0.012 15.8 0.1 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2HE PF16278.5 OAG43470.1 - 0.0016 18.8 8.2 0.14 12.6 1.4 2.3 1 1 1 2 2 2 2 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_6 PF13912.6 OAG43470.1 - 0.014 15.4 7.8 0.65 10.1 0.3 2.8 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_11 PF16622.5 OAG43470.1 - 0.2 11.5 2.6 5.1 6.9 0.2 2.5 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-met PF12874.7 OAG43470.1 - 0.36 11.3 0.2 0.36 11.3 0.2 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-BED PF02892.15 OAG43470.1 - 0.42 10.7 2.3 0.32 11.1 0.3 1.8 2 0 0 2 2 2 0 BED zinc finger zf-AN1 PF01428.16 OAG43470.1 - 4.9 7.4 9.0 18 5.6 2.1 2.3 1 1 1 2 2 2 0 AN1-like Zinc finger Aconitase PF00330.20 OAG43472.1 - 4.3e-84 283.1 0.2 7.4e-78 262.6 0.1 2.9 1 1 1 2 2 2 2 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 OAG43472.1 - 2.1e-21 76.6 0.0 4.1e-21 75.7 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF1687 PF07955.11 OAG43473.1 - 9e-30 103.8 0.1 1.2e-29 103.4 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1687) ArsC PF03960.15 OAG43473.1 - 0.0051 16.8 0.0 0.011 15.7 0.0 1.5 2 0 0 2 2 2 1 ArsC family Glyco_hydro_76 PF03663.14 OAG43474.1 - 2.8e-158 527.2 10.5 3.2e-158 527.0 10.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 OAG43474.1 - 0.096 11.7 6.2 0.77 8.8 0.1 3.0 2 1 1 3 3 3 0 Glycosyl Hydrolase Family 88 CBP4 PF07960.11 OAG43475.1 - 9.5e-21 74.0 0.2 1.1e-20 73.8 0.2 1.1 1 0 0 1 1 1 1 CBP4 DPCD PF14913.6 OAG43475.1 - 0.0006 19.2 0.2 0.00074 18.9 0.2 1.1 1 0 0 1 1 1 1 DPCD protein family Synaptobrevin PF00957.21 OAG43476.1 - 2.2e-33 113.9 1.6 2.5e-33 113.7 1.6 1.0 1 0 0 1 1 1 1 Synaptobrevin AKNA PF12443.8 OAG43476.1 - 0.05 14.3 0.0 0.081 13.6 0.0 1.3 1 1 0 1 1 1 0 AT-hook-containing transcription factor MCU PF04678.13 OAG43476.1 - 0.096 12.8 0.1 0.12 12.5 0.1 1.0 1 0 0 1 1 1 0 Mitochondrial calcium uniporter DUF1035 PF06281.12 OAG43476.1 - 0.6 10.2 3.3 0.89 9.6 3.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1035) NAT PF04768.13 OAG43477.1 - 9.3e-51 171.9 0.0 1.7e-50 171.0 0.0 1.5 1 0 0 1 1 1 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase Semialdhyde_dh PF01118.24 OAG43477.1 - 1.2e-31 109.7 0.0 2.7e-31 108.5 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.28 OAG43477.1 - 3.8e-30 105.3 0.0 7.3e-30 104.3 0.0 1.4 1 0 0 1 1 1 1 Amino acid kinase family Rad21_Rec8_N PF04825.13 OAG43477.1 - 3.2e-22 78.8 0.1 9.6e-22 77.2 0.0 1.8 2 0 0 2 2 2 1 N terminus of Rad21 / Rec8 like protein DapB_N PF01113.20 OAG43477.1 - 0.07 13.3 0.0 0.24 11.5 0.0 2.0 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Sacchrp_dh_NADP PF03435.18 OAG43477.1 - 0.081 13.2 0.0 0.22 11.8 0.0 1.8 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Sel1 PF08238.12 OAG43478.1 - 5e-46 154.1 25.0 1.9e-07 31.5 0.0 7.8 7 0 0 7 7 7 7 Sel1 repeat TPR_17 PF13431.6 OAG43478.1 - 0.032 14.6 0.1 13 6.5 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 OAG43478.1 - 1.8 9.6 4.8 2.2 9.3 0.2 3.6 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 OAG43478.1 - 8.3 7.3 14.3 6.1 7.7 0.2 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat FAD_binding_3 PF01494.19 OAG43479.1 - 6.8e-55 186.7 3.1 1.8e-50 172.1 0.3 2.1 2 0 0 2 2 2 2 FAD binding domain Phe_hydrox_dim PF07976.12 OAG43479.1 - 0.00033 20.7 0.0 0.0011 19.0 0.0 1.9 1 1 1 2 2 2 1 Phenol hydroxylase, C-terminal dimerisation domain DAO PF01266.24 OAG43479.1 - 0.0042 16.7 0.6 0.0064 16.1 0.6 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 OAG43479.1 - 0.0079 15.5 0.1 0.018 14.3 0.1 1.5 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 OAG43479.1 - 0.014 14.7 0.1 0.024 14.0 0.1 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 OAG43479.1 - 0.082 12.1 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OAG43479.1 - 0.089 11.8 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein MPC PF03650.13 OAG43480.1 - 2e-40 137.3 2.7 9.8e-36 122.2 0.1 2.3 2 0 0 2 2 2 2 Mitochondrial pyruvate carriers MtN3_slv PF03083.16 OAG43480.1 - 0.0056 16.7 0.1 0.0087 16.1 0.1 1.3 1 0 0 1 1 1 1 Sugar efflux transporter for intercellular exchange L51_S25_CI-B8 PF05047.16 OAG43481.1 - 2.8e-12 46.3 0.0 4.1e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain adh_short PF00106.25 OAG43482.1 - 5.3e-37 127.2 0.1 1.1e-36 126.2 0.1 1.5 1 0 0 1 1 1 1 short chain dehydrogenase LigB PF02900.18 OAG43482.1 - 7.2e-37 126.9 0.8 1.1e-36 126.3 0.1 1.6 2 0 0 2 2 2 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase adh_short_C2 PF13561.6 OAG43482.1 - 5.6e-26 91.5 0.1 1.1e-25 90.6 0.1 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG43482.1 - 5.9e-06 26.3 2.0 2.9e-05 24.1 0.1 2.5 3 0 0 3 3 3 1 KR domain RmlD_sub_bind PF04321.17 OAG43482.1 - 0.019 14.1 0.0 0.044 12.9 0.0 1.5 2 0 0 2 2 2 0 RmlD substrate binding domain Epimerase PF01370.21 OAG43482.1 - 0.029 13.9 0.0 0.064 12.7 0.0 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family ODR4-like PF14778.6 OAG43482.1 - 0.095 11.6 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Olfactory receptor 4-like DUF3237 PF11578.8 OAG43483.1 - 6.8e-37 126.6 0.0 9.6e-37 126.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) zf-BED PF02892.15 OAG43483.1 - 0.00031 20.7 6.0 0.15 12.1 0.4 2.3 2 0 0 2 2 2 2 BED zinc finger PyrI_C PF02748.15 OAG43483.1 - 0.46 10.4 6.2 6.9 6.7 0.6 2.4 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain RRG8 PF17068.5 OAG43484.1 - 0.034 13.6 0.0 0.063 12.7 0.0 1.3 1 0 0 1 1 1 0 Required for respiratory growth protein 8 mitochondrial Abhydrolase_6 PF12697.7 OAG43485.1 - 9.6e-18 65.6 3.1 1.2e-17 65.3 3.1 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAG43485.1 - 2.8e-07 30.4 0.1 7.8e-07 29.0 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAG43485.1 - 2.8e-06 26.8 0.1 1.6e-05 24.3 0.1 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 OAG43485.1 - 0.068 11.9 0.0 0.14 10.8 0.0 1.5 2 0 0 2 2 2 0 Ndr family FMO-like PF00743.19 OAG43486.1 - 3e-13 49.1 0.6 1.3e-11 43.7 0.2 2.7 2 1 1 3 3 3 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 OAG43486.1 - 5.1e-10 39.1 0.0 2.3e-05 23.8 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG43486.1 - 1.9e-09 37.6 0.0 5.3e-09 36.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 OAG43486.1 - 2.2e-09 37.0 0.0 1.8e-07 30.7 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAG43486.1 - 0.00017 21.6 0.1 0.019 14.9 0.0 2.9 3 0 0 3 3 3 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 OAG43486.1 - 0.00025 20.3 0.0 0.1 11.7 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 OAG43486.1 - 0.0016 17.7 0.1 0.069 12.4 0.0 2.8 3 0 0 3 3 3 1 Thi4 family DAO PF01266.24 OAG43486.1 - 0.0024 17.5 0.0 0.083 12.4 0.0 2.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase CoA_binding PF02629.19 OAG43486.1 - 0.029 15.0 0.1 2.1 9.1 0.0 2.5 2 0 0 2 2 2 0 CoA binding domain Pyr_redox PF00070.27 OAG43486.1 - 0.095 13.3 0.6 88 3.8 0.0 3.7 4 0 0 4 4 4 0 Pyridine nucleotide-disulphide oxidoreductase adh_short PF00106.25 OAG43487.1 - 3.2e-30 105.1 0.0 7.5e-30 103.9 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG43487.1 - 2.5e-20 73.0 0.0 6.3e-20 71.7 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG43487.1 - 0.0022 17.9 0.0 0.025 14.5 0.0 2.0 2 0 0 2 2 2 1 KR domain Fungal_trans PF04082.18 OAG43489.1 - 6.3e-16 58.2 0.0 9.7e-16 57.6 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain AMP-binding PF00501.28 OAG43490.1 - 2.9e-60 204.1 0.0 4e-60 203.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG43490.1 - 7.6e-10 39.6 0.0 2.7e-09 37.9 0.0 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF5083 PF16890.5 OAG43490.1 - 0.14 11.9 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5083) ACOX PF01756.19 OAG43491.1 - 2.6e-38 131.4 0.1 1.6e-37 128.9 0.0 2.3 3 0 0 3 3 3 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 OAG43491.1 - 4.9e-20 72.4 2.0 1e-19 71.3 2.0 1.6 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 OAG43491.1 - 4.2e-09 36.5 0.0 7.9e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain MFS_1 PF07690.16 OAG43492.1 - 9e-34 116.9 31.4 9e-34 116.9 31.4 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Lactamase_B PF00753.27 OAG43493.1 - 1.2e-10 41.7 1.4 2.6e-10 40.6 1.4 1.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.6 OAG43493.1 - 4e-05 23.6 0.0 7.4e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 OAG43493.1 - 6.2e-05 22.6 0.0 0.00017 21.2 0.0 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain p450 PF00067.22 OAG43494.1 - 2.1e-67 227.9 0.0 2.7e-67 227.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3392 PF11872.8 OAG43494.1 - 0.089 13.1 1.4 0.41 10.9 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3392) Fungal_trans PF04082.18 OAG43495.1 - 1e-16 60.8 0.4 1.1e-15 57.4 0.4 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Caps_synth_GfcC PF06251.11 OAG43495.1 - 0.11 12.1 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Capsule biosynthesis GfcC CAP_N PF01213.19 OAG43496.1 - 3.1e-66 224.0 0.0 3.7e-66 223.8 0.0 1.0 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal Transferase PF02458.15 OAG43497.1 - 5.7e-23 81.3 0.0 8.4e-22 77.4 0.0 2.2 2 1 0 2 2 2 2 Transferase family EBP PF05241.12 OAG43498.1 - 0.017 14.5 3.7 0.017 14.5 3.7 1.8 2 1 0 2 2 2 0 Emopamil binding protein DUF5455 PF17537.2 OAG43498.1 - 0.067 13.6 1.0 0.33 11.4 0.2 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5455) Glyco_hydro_3_C PF01915.22 OAG43499.1 - 8.3e-53 179.4 0.1 2.4e-52 177.9 0.1 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 OAG43499.1 - 1.2e-36 126.8 0.0 2.2e-36 125.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 OAG43499.1 - 1.2e-16 60.5 0.2 2.4e-16 59.6 0.2 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain PIR PF00399.19 OAG43499.1 - 1.3e-08 34.2 13.3 4.6e-05 22.9 1.7 2.6 2 0 0 2 2 2 2 Yeast PIR protein repeat Mucin-like PF16058.5 OAG43499.1 - 0.18 11.9 10.6 0.47 10.6 10.6 1.6 1 0 0 1 1 1 0 Mucin-like FAD_binding_7 PF03441.14 OAG43500.1 - 1.8e-73 246.3 0.1 2.7e-73 245.8 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 OAG43500.1 - 6.3e-34 117.3 0.1 1.2e-33 116.5 0.1 1.4 1 0 0 1 1 1 1 DNA photolyase Peptidase_M20 PF01546.28 OAG43501.1 - 1.1e-27 97.0 0.1 1.8e-27 96.4 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 OAG43501.1 - 2.9e-15 56.1 0.0 4.5e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain zf-CCCH PF00642.24 OAG43502.1 - 0.0011 18.8 3.1 0.0011 18.8 3.1 3.0 4 1 0 4 4 4 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Suppressor_APC PF11414.8 OAG43502.1 - 0.054 13.6 0.8 0.12 12.4 0.8 1.5 1 0 0 1 1 1 0 Adenomatous polyposis coli tumour suppressor protein JIP_LZII PF16471.5 OAG43502.1 - 0.056 13.6 0.8 0.12 12.6 0.8 1.5 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II Torus PF16131.5 OAG43502.1 - 7.3 7.3 8.3 0.29 11.8 1.1 2.3 2 1 0 2 2 2 0 Torus domain DASH_Spc19 PF08287.11 OAG43503.1 - 4.1e-51 173.0 2.7 5.6e-51 172.5 2.7 1.2 1 0 0 1 1 1 1 Spc19 TPR_MLP1_2 PF07926.12 OAG43503.1 - 0.024 14.7 6.4 0.18 11.9 0.0 2.5 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein Prefoldin_2 PF01920.20 OAG43503.1 - 0.044 13.7 8.2 3 7.8 4.2 2.5 3 0 0 3 3 3 0 Prefoldin subunit LPD30 PF18850.1 OAG43503.1 - 0.12 12.2 0.2 0.25 11.1 0.0 1.6 2 0 0 2 2 2 0 Large polyvalent protein associated domain 30 ADIP PF11559.8 OAG43503.1 - 0.21 11.7 10.1 1.1 9.3 2.9 3.0 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding DUF3086 PF11285.8 OAG43503.1 - 1.5 7.8 7.1 0.59 9.2 4.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3086) DivIC PF04977.15 OAG43503.1 - 2.8 7.8 8.2 8.4 6.2 0.1 2.4 2 0 0 2 2 2 0 Septum formation initiator DUF4726 PF15855.5 OAG43503.1 - 5.7 7.2 5.4 15 5.9 2.1 2.6 1 1 0 2 2 2 0 Domain of unknown function (DUF4726) ADH_zinc_N PF00107.26 OAG43504.1 - 9.4e-25 87.1 2.0 1.4e-24 86.5 2.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAG43504.1 - 1.1e-10 42.7 0.0 1.9e-10 41.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG43504.1 - 5.2e-06 26.3 2.1 1.1e-05 25.2 0.0 2.6 3 2 1 4 4 4 1 Alcohol dehydrogenase GroES-like domain ACP_syn_III_C PF08541.10 OAG43504.1 - 0.0014 18.7 0.3 0.0044 17.2 0.3 1.9 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ADH_N_2 PF16884.5 OAG43504.1 - 0.0095 15.8 0.1 0.084 12.8 0.0 2.3 2 0 0 2 2 2 1 N-terminal domain of oxidoreductase adh_short_C2 PF13561.6 OAG43505.1 - 4.4e-51 173.7 0.3 5.4e-51 173.4 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG43505.1 - 1.6e-36 125.6 0.1 2e-36 125.3 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG43505.1 - 1.5e-09 38.1 0.0 1.8e-09 37.7 0.0 1.3 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG43505.1 - 0.0085 15.6 0.0 0.022 14.2 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family DFP PF04127.15 OAG43505.1 - 0.015 15.1 1.4 0.069 13.0 0.7 2.3 2 1 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein WcbI PF18588.1 OAG43505.1 - 0.12 12.0 0.1 6.9 6.2 0.0 2.3 2 0 0 2 2 2 0 Polysaccharide biosynthesis enzyme WcbI Eno-Rase_NADH_b PF12242.8 OAG43505.1 - 0.15 11.8 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase PhyH PF05721.13 OAG43506.1 - 3.3e-19 70.0 0.0 4e-19 69.7 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) RhoGAP PF00620.27 OAG43507.1 - 1.7e-48 164.3 0.1 4.3e-48 163.0 0.0 1.7 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.23 OAG43507.1 - 1.5e-12 47.7 3.0 1.9e-12 47.2 0.2 2.4 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain T3SSipB PF16535.5 OAG43507.1 - 0.14 12.7 6.4 0.29 11.6 6.4 1.5 1 0 0 1 1 1 0 Type III cell invasion protein SipB Apolipoprotein PF01442.18 OAG43507.1 - 0.2 11.5 13.1 0.38 10.6 13.1 1.4 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF4407 PF14362.6 OAG43507.1 - 1 8.6 7.8 1.9 7.8 7.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) OmpH PF03938.14 OAG43507.1 - 1.3 9.3 9.6 2.3 8.5 6.9 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) HAUS-augmin3 PF14932.6 OAG43507.1 - 2.2 7.8 10.9 0.11 12.0 3.7 2.0 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 NmrA PF05368.13 OAG43508.1 - 1.1e-22 80.7 0.0 1.5e-22 80.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG43508.1 - 1.1e-06 28.7 0.0 2.1e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding DUF3425 PF11905.8 OAG43509.1 - 1.5e-25 89.6 0.1 2.5e-25 88.8 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_Maf PF03131.17 OAG43509.1 - 0.15 12.6 4.3 0.27 11.8 4.3 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor adh_short PF00106.25 OAG43510.1 - 8.8e-17 61.2 0.2 6.4e-16 58.4 0.1 2.3 3 1 0 3 3 3 1 short chain dehydrogenase KR PF08659.10 OAG43510.1 - 1e-10 41.8 0.2 1.4e-10 41.4 0.2 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 OAG43510.1 - 2.5e-08 33.8 0.1 8.3e-08 32.1 0.1 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 OAG43510.1 - 0.051 13.0 0.9 0.22 11.0 0.9 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family LMBR1 PF04791.16 OAG43512.1 - 0.0003 19.8 0.0 0.0004 19.4 0.0 1.1 1 0 0 1 1 1 1 LMBR1-like membrane protein MFS_1 PF07690.16 OAG43513.1 - 2.7e-41 141.7 24.4 2.7e-41 141.7 24.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG43513.1 - 2.8e-06 26.5 15.9 0.0001 21.3 0.7 3.3 2 1 1 3 3 3 2 Sugar (and other) transporter UPF0182 PF03699.13 OAG43513.1 - 0.11 10.6 1.3 0.27 9.3 0.9 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0182) Sugar_tr PF00083.24 OAG43515.1 - 1.2e-80 271.6 18.6 1.3e-80 271.4 18.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG43515.1 - 5.2e-25 88.1 31.1 8.6e-25 87.4 22.1 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Zn_clus PF00172.18 OAG43516.1 - 1.7e-06 28.0 9.7 2.8e-06 27.4 9.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.25 OAG43517.1 - 6.4e-24 84.5 0.8 7.6e-24 84.3 0.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG43517.1 - 9.1e-15 54.9 1.0 1.2e-14 54.4 1.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG43517.1 - 2e-05 24.6 0.7 3.9e-05 23.6 0.1 1.6 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 OAG43517.1 - 0.037 13.5 0.2 0.099 12.1 0.2 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family GPI2 PF06432.11 OAG43518.1 - 3.6e-122 407.2 0.1 4.2e-122 407.0 0.1 1.1 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase Aldedh PF00171.22 OAG43519.1 - 3.6e-148 493.9 0.1 4.6e-148 493.6 0.1 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Gln-synt_C PF00120.24 OAG43520.1 - 2.8e-60 204.2 0.0 5.4e-60 203.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Amidohydro_2 PF04909.14 OAG43520.1 - 2.3e-15 57.1 0.0 5.6e-15 55.9 0.0 1.6 1 0 0 1 1 1 1 Amidohydrolase Exo_endo_phos PF03372.23 OAG43521.1 - 2.3e-09 37.1 0.4 3.4e-09 36.6 0.4 1.3 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.7 OAG43522.1 - 0.038 14.4 3.3 4.5 7.8 0.1 4.7 5 1 1 6 6 6 0 Leucine Rich repeats (2 copies) MAPEG PF01124.18 OAG43523.1 - 2.1e-17 63.2 1.2 3.1e-17 62.7 1.2 1.2 1 0 0 1 1 1 1 MAPEG family Cupin_1 PF00190.22 OAG43524.1 - 2.8e-18 66.0 0.5 4.1e-18 65.4 0.5 1.3 1 0 0 1 1 1 1 Cupin DUF3535 PF12054.8 OAG43525.1 - 1.1e-116 390.7 0.0 7.5e-116 387.9 0.0 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF3535) SNF2_N PF00176.23 OAG43525.1 - 3.5e-64 216.7 0.0 1.2e-63 215.0 0.0 1.9 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OAG43525.1 - 3.7e-20 72.3 0.0 9.3e-20 71.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT PF02985.22 OAG43525.1 - 3.3e-15 54.9 3.3 0.0091 16.2 0.0 8.7 8 0 0 8 8 8 5 HEAT repeat HEAT_2 PF13646.6 OAG43525.1 - 4.8e-07 30.1 1.0 0.012 16.0 0.1 5.4 5 0 0 5 5 5 1 HEAT repeats TAF6_C PF07571.13 OAG43525.1 - 0.021 15.2 0.0 9.7 6.6 0.0 4.5 4 0 0 4 4 4 0 TAF6 C-terminal HEAT repeat domain Vac14_Fab1_bd PF12755.7 OAG43525.1 - 0.033 14.8 0.0 18 6.0 0.0 3.8 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region ERCC3_RAD25_C PF16203.5 OAG43525.1 - 0.065 12.4 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase IFRD PF05004.13 OAG43525.1 - 0.22 10.6 1.2 26 3.8 0.1 3.4 3 0 0 3 3 3 0 Interferon-related developmental regulator (IFRD) HEAT_EZ PF13513.6 OAG43525.1 - 1.2 9.8 10.5 5 7.7 0.0 5.9 7 0 0 7 7 7 0 HEAT-like repeat Ndufs5 PF10200.9 OAG43526.1 - 3.4e-05 24.0 0.0 4.6e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa DUF3128 PF11326.8 OAG43526.1 - 0.00071 19.9 1.0 0.0022 18.4 1.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3128) Sec39 PF08314.11 OAG43527.1 - 6.3e-189 630.0 0.1 7.5e-189 629.8 0.1 1.0 1 0 0 1 1 1 1 Secretory pathway protein Sec39 Vpu PF00558.19 OAG43528.1 - 0.041 13.7 0.1 0.1 12.4 0.1 1.6 2 0 0 2 2 2 0 Vpu protein TonB_C PF03544.14 OAG43529.1 - 0.17 12.4 0.0 0.35 11.3 0.0 1.5 1 0 0 1 1 1 0 Gram-negative bacterial TonB protein C-terminal WD40 PF00400.32 OAG43532.1 - 2.2e-21 75.7 20.5 0.00045 21.0 0.3 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat PD40 PF07676.12 OAG43532.1 - 0.0039 17.1 0.4 0.025 14.5 0.0 2.6 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat Kelch_6 PF13964.6 OAG43532.1 - 0.032 14.5 0.4 0.97 9.8 0.0 2.8 2 0 0 2 2 2 0 Kelch motif ANAPC4_WD40 PF12894.7 OAG43532.1 - 0.037 14.3 0.0 0.7 10.2 0.0 2.8 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 OAG43532.1 - 0.069 13.7 0.4 77 4.0 0.1 3.9 3 0 0 3 3 3 0 PQQ-like domain Cytochrom_D1 PF02239.16 OAG43532.1 - 0.084 11.4 0.6 0.61 8.6 0.0 2.5 3 0 0 3 3 3 0 Cytochrome D1 heme domain SDA1 PF05285.12 OAG43532.1 - 0.79 9.1 7.0 1.3 8.4 7.0 1.3 1 0 0 1 1 1 0 SDA1 Ank_2 PF12796.7 OAG43533.1 - 1.8e-40 137.4 3.1 1e-11 45.3 0.1 5.1 2 2 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OAG43533.1 - 1.2e-30 102.1 2.2 2.5e-05 24.3 0.0 8.5 8 0 0 8 8 8 7 Ankyrin repeat Ank PF00023.30 OAG43533.1 - 2.4e-29 100.5 5.8 0.0005 20.4 0.0 8.0 7 0 0 7 7 7 7 Ankyrin repeat Ank_4 PF13637.6 OAG43533.1 - 1.4e-27 95.7 4.7 2e-07 31.4 0.0 6.0 4 3 3 7 7 7 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 OAG43533.1 - 2.9e-24 84.8 4.7 2e-07 31.1 0.2 6.6 3 1 4 7 7 7 6 Ankyrin repeats (many copies) CorA PF01544.18 OAG43533.1 - 7e-10 38.7 0.2 1.7e-09 37.5 0.2 1.6 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF2207 PF09972.9 OAG43533.1 - 0.043 12.6 0.0 0.075 11.8 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Glyoxalase PF00903.25 OAG43534.1 - 5.4e-09 36.3 0.0 2.1e-08 34.4 0.0 1.8 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 OAG43534.1 - 2.7e-06 27.6 0.0 4.1e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 OAG43534.1 - 8.8e-06 25.9 0.0 2.2e-05 24.6 0.0 1.6 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_6 PF18029.1 OAG43534.1 - 0.0017 19.1 0.0 0.0043 17.8 0.0 1.7 1 1 0 1 1 1 1 Glyoxalase-like domain Fungal_trans PF04082.18 OAG43535.1 - 2.6e-21 75.8 0.6 4.9e-21 74.9 0.6 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain PEP_mutase PF13714.6 OAG43537.1 - 3.4e-43 147.8 0.1 4.2e-43 147.5 0.1 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 OAG43537.1 - 1.6e-18 66.5 0.3 2.2e-18 66.1 0.3 1.1 1 0 0 1 1 1 1 Isocitrate lyase family Aconitase PF00330.20 OAG43538.1 - 9.1e-71 239.2 0.0 6.3e-69 233.2 0.0 2.1 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 OAG43538.1 - 2.2e-13 50.7 0.0 4.5e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain Fructosamin_kin PF03881.14 OAG43539.1 - 7.3e-35 120.6 0.0 9.9e-35 120.1 0.0 1.1 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 OAG43539.1 - 2.1e-05 24.6 0.0 3.1e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family ANAPC4_WD40 PF12894.7 OAG43540.1 - 2.2e-06 27.9 0.0 0.56 10.5 0.0 4.3 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PGAP1 PF07819.13 OAG43540.1 - 0.00015 21.5 0.0 0.001 18.8 0.0 2.2 3 0 0 3 3 3 1 PGAP1-like protein Abhydrolase_6 PF12697.7 OAG43540.1 - 0.012 16.2 0.0 0.033 14.8 0.0 1.8 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF676 PF05057.14 OAG43540.1 - 0.013 15.1 0.0 0.036 13.6 0.0 1.7 1 0 0 1 1 1 0 Putative serine esterase (DUF676) WD40 PF00400.32 OAG43540.1 - 0.026 15.4 2.1 0.17 12.8 0.2 3.5 4 0 0 4 4 4 0 WD domain, G-beta repeat 6PF2K PF01591.18 OAG43540.1 - 0.047 13.0 0.0 0.092 12.0 0.0 1.4 1 0 0 1 1 1 0 6-phosphofructo-2-kinase Hydrolase_4 PF12146.8 OAG43540.1 - 0.062 12.5 0.1 0.57 9.4 0.0 2.1 2 0 0 2 2 2 0 Serine aminopeptidase, S33 LCAT PF02450.15 OAG43540.1 - 0.12 11.6 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase MFS_1 PF07690.16 OAG43541.1 - 9.1e-42 143.2 31.8 5.3e-40 137.4 13.4 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG43541.1 - 6.1e-15 55.0 7.7 6.1e-15 55.0 7.7 2.7 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 OAG43541.1 - 8.1e-05 21.2 1.6 8.1e-05 21.2 1.6 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MmgE_PrpD PF03972.14 OAG43542.1 - 4.4e-115 384.7 0.0 5.2e-115 384.5 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family SLBP_RNA_bind PF15247.6 OAG43543.1 - 0.14 12.3 1.8 0.26 11.4 1.8 1.4 1 0 0 1 1 1 0 Histone RNA hairpin-binding protein RNA-binding domain KIAA1328 PF15369.6 OAG43543.1 - 3 7.6 5.1 3.1 7.6 5.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein KIAA1328 LRR_4 PF12799.7 OAG43544.1 - 0.076 13.5 0.0 28 5.3 0.0 2.8 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) DUF4185 PF13810.6 OAG43545.1 - 7.6e-07 28.7 1.1 1.4e-06 27.8 0.1 1.9 2 1 0 2 2 2 1 Domain of unknown function (DUF4185) PAN_1 PF00024.26 OAG43545.1 - 0.0085 16.0 0.3 0.016 15.1 0.3 1.4 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.6 OAG43545.1 - 0.012 15.5 0.3 0.043 13.7 0.3 2.0 1 1 0 1 1 1 0 PAN domain DUF2510 PF10708.9 OAG43545.1 - 0.11 12.3 3.2 0.86 9.4 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2510) EI24 PF07264.11 OAG43546.1 - 1.4e-13 51.5 0.6 2.3e-13 50.8 0.6 1.3 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Ras PF00071.22 OAG43547.1 - 7.8e-56 188.2 0.0 9.6e-56 187.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAG43547.1 - 8.9e-34 116.3 0.0 1.4e-33 115.6 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAG43547.1 - 3.7e-13 49.3 0.0 1.2e-12 47.6 0.0 1.6 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OAG43547.1 - 8.1e-06 25.5 0.0 1.4e-05 24.7 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OAG43547.1 - 9.4e-05 21.9 0.0 0.00013 21.4 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OAG43547.1 - 0.00015 21.9 0.0 0.00024 21.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 OAG43547.1 - 0.026 14.9 0.8 0.057 13.8 0.8 1.8 1 1 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 OAG43547.1 - 0.031 14.2 0.0 2 8.3 0.0 2.5 2 1 0 2 2 2 0 RsgA GTPase ING PF12998.7 OAG43548.1 - 5.5e-07 30.1 0.0 1e-06 29.2 0.0 1.5 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding LIDHydrolase PF10230.9 OAG43549.1 - 0.022 14.3 0.0 0.037 13.6 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Ribosomal_S14 PF00253.21 OAG43550.1 - 4.7e-21 74.3 2.2 2.5e-20 72.0 1.3 2.0 2 0 0 2 2 2 1 Ribosomal protein S14p/S29e QLQ PF08880.11 OAG43550.1 - 0.021 14.6 0.0 0.044 13.5 0.0 1.5 1 0 0 1 1 1 0 QLQ ABC_tran PF00005.27 OAG43551.1 - 1.4e-39 135.8 1.2 3e-21 76.4 0.0 3.7 3 1 0 3 3 3 2 ABC transporter SMC_N PF02463.19 OAG43551.1 - 6.4e-13 48.6 0.4 0.00071 19.1 0.2 4.3 3 2 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 OAG43551.1 - 1.7e-12 47.8 8.6 8.5e-05 22.5 0.8 4.3 3 1 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran_Xtn PF12848.7 OAG43551.1 - 4.4e-10 39.4 7.1 4.4e-10 39.4 7.1 2.3 2 0 0 2 2 2 1 ABC transporter AAA_29 PF13555.6 OAG43551.1 - 1.8e-06 27.6 0.0 0.084 12.6 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 OAG43551.1 - 1.2e-05 25.9 9.5 0.032 14.7 0.0 4.0 4 0 0 4 4 4 2 AAA domain MMR_HSR1 PF01926.23 OAG43551.1 - 4.6e-05 23.5 2.3 0.19 11.8 0.1 3.3 3 1 0 3 3 3 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OAG43551.1 - 6.8e-05 22.8 3.0 0.075 12.9 0.0 3.4 3 1 0 4 4 4 2 RsgA GTPase AAA_18 PF13238.6 OAG43551.1 - 0.00015 22.3 0.4 0.99 10.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 OAG43551.1 - 0.00046 20.5 0.7 0.00046 20.5 0.7 3.2 3 1 0 3 3 2 1 AAA domain AAA PF00004.29 OAG43551.1 - 0.0018 18.7 2.7 0.89 10.0 0.0 3.9 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OAG43551.1 - 0.0018 18.7 9.0 0.29 11.5 3.0 3.2 3 1 0 3 3 3 2 AAA ATPase domain AAA_33 PF13671.6 OAG43551.1 - 0.0022 18.1 7.2 0.36 11.0 0.2 3.2 3 0 0 3 3 3 2 AAA domain FtsK_SpoIIIE PF01580.18 OAG43551.1 - 0.0023 17.3 0.1 1.3 8.4 0.0 2.7 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_25 PF13481.6 OAG43551.1 - 0.0039 16.8 4.5 1.9 8.0 1.6 3.5 2 2 0 2 2 2 2 AAA domain NACHT PF05729.12 OAG43551.1 - 0.0061 16.5 3.8 3.2 7.7 0.2 3.4 3 1 0 4 4 4 2 NACHT domain DUF815 PF05673.13 OAG43551.1 - 0.0064 15.7 6.5 0.045 12.9 0.0 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF815) DUF5615 PF18480.1 OAG43551.1 - 0.0069 16.1 0.8 2.7 7.8 0.1 3.5 3 0 0 3 3 3 1 Domain of unknown function (DUF5615) AAA_5 PF07728.14 OAG43551.1 - 0.025 14.6 6.5 1.2 9.2 0.1 3.9 3 1 1 4 4 4 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 OAG43551.1 - 0.038 14.4 0.1 14 6.2 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_22 PF13401.6 OAG43551.1 - 0.043 14.1 7.5 0.42 10.9 0.1 3.8 3 2 0 3 3 3 0 AAA domain SbcCD_C PF13558.6 OAG43551.1 - 0.056 13.7 0.9 0.5 10.6 0.1 3.0 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit PIN7 PF18475.1 OAG43551.1 - 0.079 13.6 0.0 0.37 11.4 0.0 2.1 2 0 0 2 2 1 0 PIN domain Roc PF08477.13 OAG43551.1 - 0.094 12.9 0.0 22 5.3 0.0 3.1 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase AAA_15 PF13175.6 OAG43551.1 - 0.17 11.6 4.4 1.4 8.6 0.0 3.2 4 0 0 4 4 4 0 AAA ATPase domain Dynamin_N PF00350.23 OAG43551.1 - 1.5 8.8 7.2 5.6 7.0 0.3 3.6 3 1 0 3 3 3 0 Dynamin family AAA_13 PF13166.6 OAG43551.1 - 7.1 5.1 14.4 3.4 6.2 0.0 3.8 3 1 0 3 3 3 0 AAA domain Metallophos PF00149.28 OAG43552.1 - 6.9e-11 43.0 2.1 1.2e-10 42.3 2.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Luteo_coat PF00894.18 OAG43552.1 - 0.023 14.6 0.0 0.067 13.1 0.0 1.8 1 0 0 1 1 1 0 Luteovirus coat protein Fungal_trans PF04082.18 OAG43553.1 - 2.3e-16 59.7 0.0 3.5e-16 59.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG43553.1 - 0.00028 20.9 9.0 0.00052 20.1 9.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HpcH_HpaI PF03328.14 OAG43554.1 - 3.9e-39 134.1 0.0 6e-39 133.5 0.0 1.2 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family HEAT_PBS PF03130.16 OAG43554.1 - 0.064 14.0 0.5 70 4.5 0.0 3.7 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat MFS_1 PF07690.16 OAG43556.1 - 1.1e-09 37.8 47.4 0.0004 19.4 17.5 3.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.18 OAG43557.1 - 2.4e-08 33.4 0.1 5.3e-08 32.2 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Melibiase_2 PF16499.5 OAG43558.1 - 3.1e-56 190.6 9.7 7.4e-55 186.1 9.7 2.2 1 1 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 OAG43558.1 - 1.2e-08 34.9 0.1 3.9e-07 30.0 0.0 2.5 2 0 0 2 2 2 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 OAG43558.1 - 1.9e-05 23.8 0.3 4.1e-05 22.7 0.1 1.5 1 1 1 2 2 2 1 Melibiase Sugar_tr PF00083.24 OAG43559.1 - 2.9e-70 237.4 23.0 3.4e-70 237.2 23.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG43559.1 - 7.9e-14 51.3 42.8 8.6e-14 51.2 37.3 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 OAG43559.1 - 2.9e-06 26.8 3.0 2.9e-06 26.8 3.0 2.1 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB MFS_1_like PF12832.7 OAG43559.1 - 0.21 10.4 26.1 0.029 13.2 6.3 2.6 2 1 0 3 3 3 0 MFS_1 like family MFS_3 PF05977.13 OAG43559.1 - 0.71 8.2 13.2 0.0081 14.6 1.9 2.1 2 0 0 2 2 2 0 Transmembrane secretion effector NT-C2 PF10358.9 OAG43560.1 - 1.4e-32 112.5 0.0 2.3e-32 111.7 0.0 1.4 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins SLS PF14611.6 OAG43560.1 - 1.4e-10 41.4 0.0 4.1e-10 39.9 0.0 1.8 1 0 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator Peptidase_C58 PF03543.14 OAG43560.1 - 0.012 15.4 1.5 0.029 14.1 1.5 1.6 1 0 0 1 1 1 0 Yersinia/Haemophilus virulence surface antigen Spt20 PF12090.8 OAG43560.1 - 4.3 6.9 10.0 2.4 7.7 6.9 2.0 2 0 0 2 2 2 0 Spt20 family NAD_binding_1 PF00175.21 OAG43561.1 - 1.3e-27 96.6 0.0 2.8e-27 95.5 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 OAG43561.1 - 3.2e-15 56.3 0.0 1.4e-14 54.2 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 OAG43561.1 - 7.1e-06 26.2 0.0 0.00045 20.4 0.0 2.3 1 1 1 2 2 2 1 Ferric reductase NAD binding domain Ubiquitin_3 PF14836.6 OAG43562.1 - 0.0048 16.9 0.4 0.011 15.8 0.4 1.5 1 0 0 1 1 1 1 Ubiquitin-like domain DUF3074 PF11274.8 OAG43563.1 - 3.3e-58 196.7 0.0 3.3e-58 196.7 0.0 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF3074) DUF4407 PF14362.6 OAG43563.1 - 1.7 7.9 19.0 2.7 7.3 19.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DAO PF01266.24 OAG43564.1 - 1.4e-47 163.0 0.1 1.7e-47 162.8 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAG43564.1 - 8.9e-05 22.6 0.1 0.00022 21.4 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 OAG43564.1 - 0.0005 19.5 0.0 0.024 13.9 0.0 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 OAG43564.1 - 0.00074 19.5 0.1 1.6 8.7 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 OAG43564.1 - 0.0019 17.6 0.0 0.046 13.0 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OAG43564.1 - 0.006 15.7 0.0 2.5 7.0 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox_2 PF07992.14 OAG43564.1 - 0.0075 15.5 0.0 0.031 13.5 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAG43564.1 - 0.0094 15.2 0.0 0.016 14.5 0.0 1.2 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 OAG43564.1 - 0.024 13.4 0.0 1.3 7.7 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_2 PF00890.24 OAG43564.1 - 0.025 13.7 0.1 0.1 11.6 0.1 1.9 1 1 0 1 1 1 0 FAD binding domain SIMPL PF04402.14 OAG43565.1 - 3.7e-23 83.0 0.3 4.1e-23 82.9 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF541) dCMP_cyt_deam_1 PF00383.23 OAG43567.1 - 9.7e-10 38.2 0.0 1.4e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 OAG43567.1 - 6.1e-08 32.5 0.0 9.1e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 MafB19-like deaminase GTP_cyclohydroI PF01227.22 OAG43567.1 - 0.15 11.5 0.1 0.19 11.1 0.1 1.2 1 0 0 1 1 1 0 GTP cyclohydrolase I Bd3614-deam PF14439.6 OAG43567.1 - 0.22 11.6 0.3 6 6.9 0.3 2.3 1 1 0 1 1 1 0 Bd3614-like deaminase adh_short_C2 PF13561.6 OAG43568.1 - 2.2e-63 213.9 1.9 2.5e-63 213.8 1.9 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG43568.1 - 1.4e-53 181.3 1.3 1.6e-53 181.1 1.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG43568.1 - 5.5e-08 32.9 0.5 9.4e-08 32.2 0.5 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG43568.1 - 9.3e-07 28.5 0.6 3.7e-06 26.6 0.6 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.26 OAG43568.1 - 0.0046 16.9 0.3 0.01 15.8 0.3 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 3Beta_HSD PF01073.19 OAG43568.1 - 0.0059 15.7 0.1 0.022 13.8 0.1 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 OAG43568.1 - 0.043 12.9 0.2 0.36 9.9 0.1 2.1 2 0 0 2 2 2 0 RmlD substrate binding domain Ribosomal_S11 PF00411.19 OAG43568.1 - 0.051 14.0 0.3 0.13 12.7 0.3 1.8 1 1 0 1 1 1 0 Ribosomal protein S11 THF_DHG_CYH_C PF02882.19 OAG43568.1 - 0.078 12.3 0.1 0.22 10.9 0.0 1.7 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 2-Hacid_dh_C PF02826.19 OAG43568.1 - 0.12 11.7 0.1 0.2 11.0 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UCR_Fe-S_N PF10399.9 OAG43568.1 - 0.37 10.2 2.0 0.46 9.9 0.0 2.1 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal adh_short_C2 PF13561.6 OAG43569.1 - 9.7e-18 64.6 1.6 2.4e-13 50.2 0.0 2.5 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG43569.1 - 1.4e-15 57.3 0.2 3.5e-07 29.9 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 OAG43569.1 - 0.0032 17.4 0.2 0.0056 16.6 0.2 1.4 1 0 0 1 1 1 1 KR domain Cutinase PF01083.22 OAG43570.1 - 7.1e-31 107.5 0.3 9.3e-31 107.1 0.3 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 OAG43570.1 - 0.02 14.4 0.0 0.033 13.7 0.0 1.2 1 0 0 1 1 1 0 PE-PPE domain zf-C2H2_2 PF12756.7 OAG43571.1 - 0.046 14.1 0.7 0.23 11.8 0.2 2.1 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 OAG43571.1 - 0.052 14.0 0.7 0.093 13.2 0.7 1.4 1 0 0 1 1 1 0 Zinc-finger of C2H2 type Pyr_redox_3 PF13738.6 OAG43572.1 - 7e-05 22.2 0.0 9.9e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 OAG43572.1 - 0.00072 18.1 0.0 0.0012 17.3 0.0 1.3 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OAG43572.1 - 0.038 14.2 0.0 0.084 13.1 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 OAG43572.1 - 0.049 12.8 0.0 0.063 12.4 0.0 1.1 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Beta-lactamase PF00144.24 OAG43573.1 - 1.4e-45 156.0 0.4 1.6e-24 86.8 0.0 2.1 2 0 0 2 2 2 2 Beta-lactamase Peptidase_S11 PF00768.20 OAG43573.1 - 0.093 12.1 0.0 1.6 8.1 0.0 2.1 2 0 0 2 2 2 0 D-alanyl-D-alanine carboxypeptidase CFEM PF05730.11 OAG43574.1 - 1.3e-13 50.8 12.9 1.9e-13 50.3 12.9 1.3 1 0 0 1 1 1 1 CFEM domain ADH_zinc_N PF00107.26 OAG43574.1 - 1e-06 28.8 0.0 2.3e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF3530 PF12048.8 OAG43574.1 - 0.038 13.4 0.2 0.049 13.1 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) Fungal_trans PF04082.18 OAG43576.1 - 2.1e-13 49.9 0.0 4.1e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG43576.1 - 1.9e-05 24.7 10.4 4.7e-05 23.4 10.4 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_4 PF13894.6 OAG43576.1 - 2.6e-05 24.7 2.2 0.00013 22.5 2.2 2.2 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2 PF00096.26 OAG43576.1 - 0.0018 18.7 2.4 0.0053 17.1 2.4 1.9 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2HC_2 PF13913.6 OAG43576.1 - 0.032 14.1 0.1 0.065 13.1 0.1 1.5 1 0 0 1 1 1 0 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.8 OAG43576.1 - 0.033 14.5 1.0 0.076 13.3 1.0 1.6 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 OAG43576.1 - 0.93 9.6 2.9 2 8.5 2.9 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger HET PF06985.11 OAG43577.1 - 5.2e-23 82.0 0.0 8.5e-23 81.3 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Alpha-L-AF_C PF06964.12 OAG43578.1 - 5.3e-27 95.0 0.0 7.6e-27 94.5 0.0 1.2 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain Glyco_hydro_44 PF12891.7 OAG43578.1 - 0.012 15.6 0.2 0.042 13.8 0.2 1.9 1 1 0 1 1 1 0 Glycoside hydrolase family 44 Ribosomal_L32p PF01783.23 OAG43578.1 - 0.22 11.8 0.4 0.81 10.0 0.0 2.0 2 0 0 2 2 2 0 Ribosomal L32p protein family Sugar_tr PF00083.24 OAG43579.1 - 4.2e-103 345.6 17.8 4.8e-103 345.4 17.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG43579.1 - 1.9e-23 83.0 34.5 2.2e-18 66.3 16.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MatC_N PF07158.11 OAG43579.1 - 0.12 12.4 3.8 0.12 12.4 1.5 2.0 2 0 0 2 2 2 0 Dicarboxylate carrier protein MatC N-terminus Lig_chan PF00060.26 OAG43579.1 - 0.32 10.8 2.5 1.1 9.1 0.1 2.5 2 0 0 2 2 2 0 Ligand-gated ion channel GST_N PF02798.20 OAG43580.1 - 2e-13 50.5 0.0 9.9e-13 48.2 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 OAG43580.1 - 1.5e-10 41.3 0.0 5.9e-10 39.4 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OAG43580.1 - 1.4e-09 38.1 0.0 2e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 OAG43580.1 - 1.1e-08 35.2 0.0 2.3e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAG43580.1 - 1.6e-07 31.2 0.0 3.6e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain PsbH PF00737.20 OAG43580.1 - 0.028 14.2 0.3 0.048 13.4 0.3 1.4 1 0 0 1 1 1 0 Photosystem II 10 kDa phosphoprotein TMEM192 PF14802.6 OAG43581.1 - 0.77 8.8 10.0 0.29 10.2 6.8 1.8 2 0 0 2 2 2 0 TMEM192 family TEX29 PF15839.5 OAG43581.1 - 5.9 7.6 7.1 18 6.0 1.2 2.7 2 1 1 3 3 3 0 Testis-expressed sequence 29 protein Fungal_trans PF04082.18 OAG43583.1 - 1.8e-07 30.5 0.0 2.7e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain ABC2_membrane PF01061.24 OAG43584.1 - 3.9e-29 101.6 27.6 8e-29 100.6 27.6 1.5 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 OAG43584.1 - 3.9e-25 89.0 0.3 6.4e-25 88.3 0.3 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 OAG43584.1 - 5.1e-07 29.4 0.1 8.3e-07 28.7 0.1 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 OAG43584.1 - 9.2e-06 25.7 0.5 9.3e-05 22.4 0.4 2.1 2 0 0 2 2 2 1 RsgA GTPase ABC2_membrane_3 PF12698.7 OAG43584.1 - 9.5e-06 24.9 14.2 1.3e-05 24.5 12.6 1.9 1 1 1 2 2 2 1 ABC-2 family transporter protein AAA_21 PF13304.6 OAG43584.1 - 0.00012 22.1 0.1 0.43 10.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SRP54 PF00448.22 OAG43584.1 - 0.00022 20.9 0.5 0.00037 20.2 0.1 1.6 2 0 0 2 2 1 1 SRP54-type protein, GTPase domain AAA_16 PF13191.6 OAG43584.1 - 0.00023 21.6 0.1 0.00042 20.7 0.1 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 OAG43584.1 - 0.00073 19.2 0.1 0.0015 18.1 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 OAG43584.1 - 0.0015 18.8 0.1 0.0063 16.8 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_13 PF13166.6 OAG43584.1 - 0.0027 16.5 0.1 0.089 11.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 OAG43584.1 - 0.012 15.3 0.4 0.035 13.8 0.4 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_28 PF13521.6 OAG43584.1 - 0.013 15.7 0.0 0.028 14.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 OAG43584.1 - 0.013 16.0 0.0 0.03 14.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 OAG43584.1 - 0.014 15.8 0.2 0.054 13.9 0.2 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Phosphoprotein PF00922.17 OAG43584.1 - 0.015 15.0 0.0 0.03 13.9 0.0 1.4 1 0 0 1 1 1 0 Vesiculovirus phosphoprotein SbcCD_C PF13558.6 OAG43584.1 - 0.017 15.4 0.0 0.069 13.4 0.0 2.1 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 OAG43584.1 - 0.021 14.6 0.1 0.036 13.8 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 OAG43584.1 - 0.025 14.9 0.1 0.045 14.1 0.1 1.4 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 OAG43584.1 - 0.027 14.1 0.0 0.044 13.4 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain T2SSE PF00437.20 OAG43584.1 - 0.042 12.9 0.2 0.067 12.2 0.2 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Rad17 PF03215.15 OAG43584.1 - 0.043 13.7 0.0 0.073 13.0 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_5 PF07728.14 OAG43584.1 - 0.044 13.8 0.0 0.14 12.1 0.1 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 OAG43584.1 - 0.056 12.6 0.0 0.092 11.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_33 PF13671.6 OAG43584.1 - 0.08 13.1 0.3 0.2 11.8 0.3 1.7 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 OAG43584.1 - 0.081 12.8 0.2 0.14 12.1 0.2 1.3 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.22 OAG43584.1 - 0.096 13.1 0.0 0.2 12.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase KAP_NTPase PF07693.14 OAG43584.1 - 0.12 11.6 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain IBR PF01485.21 OAG43585.1 - 1.4e-05 25.3 27.9 4.7e-05 23.5 6.2 3.8 4 0 0 4 4 4 3 IBR domain, a half RING-finger domain FYVE PF01363.21 OAG43585.1 - 0.6 10.3 31.0 1 9.5 4.2 4.4 4 1 0 4 4 4 0 FYVE zinc finger MAGE PF01454.19 OAG43586.1 - 5.7e-59 199.4 0.1 8.9e-59 198.7 0.1 1.3 1 0 0 1 1 1 1 MAGE family TPR_1 PF00515.28 OAG43587.1 - 1.1e-29 101.0 13.3 7.6e-07 28.7 1.0 7.2 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_2 PF07719.17 OAG43587.1 - 6.8e-28 94.5 13.1 0.00013 21.8 0.6 7.6 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_11 PF13414.6 OAG43587.1 - 1.7e-22 78.8 15.4 1.4e-06 27.9 0.2 6.6 4 2 2 6 6 6 6 TPR repeat TPR_19 PF14559.6 OAG43587.1 - 5.2e-22 78.1 19.9 0.00013 22.4 0.7 6.3 7 0 0 7 7 6 5 Tetratricopeptide repeat DnaJ PF00226.31 OAG43587.1 - 6e-19 67.9 3.3 6e-19 67.9 3.3 2.5 2 0 0 2 2 2 1 DnaJ domain TPR_8 PF13181.6 OAG43587.1 - 1.5e-15 56.0 13.7 0.0017 18.4 0.6 6.9 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_17 PF13431.6 OAG43587.1 - 4.6e-14 51.7 14.8 0.034 14.5 0.3 6.9 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_16 PF13432.6 OAG43587.1 - 1e-13 51.7 12.9 0.0089 16.7 0.0 6.0 3 2 3 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.6 OAG43587.1 - 5.3e-13 48.6 10.4 0.067 14.1 0.2 7.1 3 2 2 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 OAG43587.1 - 1.8e-12 46.4 11.8 0.013 15.5 0.2 7.3 7 0 0 7 7 7 3 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 OAG43587.1 - 4.3e-09 36.3 5.3 0.0011 18.9 0.1 4.9 4 2 2 6 6 6 2 Fis1 C-terminal tetratricopeptide repeat TPR_12 PF13424.6 OAG43587.1 - 1.8e-08 34.6 9.2 0.55 10.6 0.4 5.9 4 2 1 5 5 5 3 Tetratricopeptide repeat ANAPC3 PF12895.7 OAG43587.1 - 1.8e-08 34.5 2.5 4.2e-05 23.7 0.3 3.7 2 1 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 BTAD PF03704.17 OAG43587.1 - 6.8e-08 33.1 4.6 0.0077 16.7 0.2 4.4 2 1 2 4 4 4 2 Bacterial transcriptional activator domain TPR_9 PF13371.6 OAG43587.1 - 7.9e-07 29.1 7.9 0.00011 22.3 0.3 4.0 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 OAG43587.1 - 0.00025 21.5 18.0 8.3 7.3 0.0 7.8 7 1 1 8 8 7 0 Tetratricopeptide repeat TPR_10 PF13374.6 OAG43587.1 - 0.0037 17.1 12.9 1.5 8.8 0.0 6.8 7 0 0 7 7 7 1 Tetratricopeptide repeat TOM20_plant PF06552.12 OAG43587.1 - 0.0067 16.2 9.1 0.13 12.0 0.1 4.0 3 2 1 4 4 4 1 Plant specific mitochondrial import receptor subunit TOM20 ChAPs PF09295.10 OAG43587.1 - 0.027 13.5 0.9 0.69 8.8 0.1 2.2 2 0 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) SHNi-TPR PF10516.9 OAG43587.1 - 0.043 13.3 1.1 14 5.3 0.0 4.5 5 0 0 5 5 5 0 SHNi-TPR MIT PF04212.18 OAG43587.1 - 0.1 12.7 3.2 30 4.8 0.2 4.3 3 1 0 3 3 3 0 MIT (microtubule interacting and transport) domain RPT PF13446.6 OAG43587.1 - 0.73 9.8 3.2 2.5 8.1 0.1 3.3 3 0 0 3 3 3 0 A repeated domain in UCH-protein Aa_trans PF01490.18 OAG43588.1 - 5.6e-42 143.9 34.1 6.7e-42 143.6 34.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.6 OAG43588.1 - 5.7e-06 25.4 53.4 0.00036 19.5 52.8 2.0 1 1 0 1 1 1 1 Amino acid permease NADH_Oxid_Nqo15 PF11497.8 OAG43588.1 - 0.18 11.8 0.2 3.3 7.8 0.1 2.2 2 0 0 2 2 2 0 NADH-quinone oxidoreductase chain 15 MSP1a PF11670.8 OAG43588.1 - 2.9 7.1 7.5 4.3 6.5 6.2 1.8 1 1 0 1 1 1 0 Major surface protein 1a (MSP1a) Kelch_5 PF13854.6 OAG43589.1 - 1.3e-12 47.4 10.7 8.1e-11 41.7 0.3 4.8 4 0 0 4 4 4 1 Kelch motif Kelch_4 PF13418.6 OAG43589.1 - 7.2e-09 35.5 15.0 0.00014 21.8 0.1 5.8 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_6 PF13964.6 OAG43589.1 - 7.2e-06 26.1 8.6 0.21 11.9 0.1 5.0 5 0 0 5 5 5 2 Kelch motif DUF4690 PF15756.5 OAG43589.1 - 0.00065 20.2 0.4 0.0019 18.7 0.4 1.8 1 0 0 1 1 1 1 Small Novel Rich in Cartilage VSP PF03302.13 OAG43589.1 - 0.00081 18.3 0.0 0.0013 17.6 0.0 1.3 1 0 0 1 1 1 1 Giardia variant-specific surface protein Podoplanin PF05808.11 OAG43589.1 - 0.018 15.2 1.4 0.028 14.5 0.2 1.9 2 0 0 2 2 2 0 Podoplanin Kelch_3 PF13415.6 OAG43589.1 - 0.11 12.8 18.2 0.32 11.3 0.2 5.3 6 1 0 6 6 6 0 Galactose oxidase, central domain Kelch_2 PF07646.15 OAG43589.1 - 0.34 11.0 3.0 47 4.2 0.0 4.1 4 1 0 4 4 4 0 Kelch motif Kelch_1 PF01344.25 OAG43589.1 - 8.7 6.0 13.2 0.37 10.4 0.3 4.5 6 0 0 6 6 6 0 Kelch motif UPF0016 PF01169.19 OAG43591.1 - 8.9e-41 138.1 25.2 1e-20 73.8 9.9 2.3 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 DUF3357 PF11837.8 OAG43591.1 - 0.026 15.0 2.6 5.5 7.5 0.8 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF3357) Methyltrn_RNA_3 PF02598.17 OAG43592.1 - 2.8e-111 371.6 0.0 3.3e-111 371.4 0.0 1.1 1 0 0 1 1 1 1 Putative RNA methyltransferase NMO PF03060.15 OAG43593.1 - 1.7e-30 106.5 9.3 6.4e-30 104.7 9.3 1.8 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 OAG43593.1 - 5.2e-06 25.7 0.1 9e-06 24.9 0.1 1.3 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 OAG43593.1 - 0.00025 20.2 0.9 0.00029 20.0 0.9 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 OAG43593.1 - 0.072 12.2 0.7 0.1 11.7 0.7 1.1 1 0 0 1 1 1 0 Conserved region in glutamate synthase Lactamase_B PF00753.27 OAG43594.1 - 3.2e-12 46.9 0.1 6e-12 46.0 0.1 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OAG43594.1 - 0.021 14.3 0.1 0.045 13.3 0.1 1.6 1 0 0 1 1 1 0 Beta-lactamase superfamily domain FAD_binding_3 PF01494.19 OAG43595.1 - 7e-25 88.0 0.0 4.6e-12 45.9 0.0 3.1 3 0 0 3 3 3 3 FAD binding domain DAO PF01266.24 OAG43595.1 - 6.1e-07 29.3 0.0 0.0014 18.3 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG43595.1 - 0.00045 19.5 0.1 0.055 12.7 0.0 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG43595.1 - 0.00055 20.1 0.0 0.0015 18.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 OAG43595.1 - 0.022 13.5 0.6 0.043 12.5 0.1 1.7 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox PF00070.27 OAG43595.1 - 0.033 14.7 0.0 0.25 11.9 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAG43595.1 - 0.05 12.7 0.0 0.077 12.1 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 OAG43595.1 - 0.055 12.5 0.1 0.17 10.9 0.1 2.0 2 1 0 2 2 2 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 OAG43595.1 - 0.067 12.4 0.0 0.34 10.1 0.0 2.1 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 OAG43595.1 - 0.071 12.8 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.20 OAG43595.1 - 0.094 12.8 0.0 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.17 OAG43595.1 - 0.14 11.3 0.1 0.23 10.7 0.1 1.3 1 0 0 1 1 1 0 Thi4 family 3HCDH_N PF02737.18 OAG43595.1 - 0.19 11.6 0.5 0.69 9.8 0.0 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_23 PF13489.6 OAG43596.1 - 3.9e-23 82.1 0.0 5.5e-23 81.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG43596.1 - 1.6e-10 41.6 0.0 3.6e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG43596.1 - 7.1e-09 35.6 0.0 8.5e-08 32.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG43596.1 - 1.2e-07 32.4 0.0 5.3e-07 30.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG43596.1 - 6.2e-06 26.8 0.0 1.1e-05 25.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 OAG43596.1 - 5.5e-05 22.7 0.0 8.4e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.14 OAG43596.1 - 0.0025 17.4 0.0 0.0043 16.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.19 OAG43596.1 - 0.0048 17.0 0.0 0.0087 16.2 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Ubie_methyltran PF01209.18 OAG43596.1 - 0.075 12.4 0.0 0.7 9.2 0.0 2.1 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 OAG43596.1 - 0.077 12.3 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain PCMT PF01135.19 OAG43596.1 - 0.087 12.6 0.0 0.42 10.3 0.0 1.9 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.20 OAG43596.1 - 0.19 11.0 0.0 0.29 10.4 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase HET PF06985.11 OAG43597.1 - 1.3e-20 74.2 0.0 3.3e-20 72.9 0.0 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) RHINO PF15319.6 OAG43597.1 - 0.1 12.6 0.3 0.21 11.6 0.3 1.4 1 0 0 1 1 1 0 RAD9, RAD1, HUS1-interacting nuclear orphan protein Pyr_redox_2 PF07992.14 OAG43598.1 - 2.1e-09 37.0 0.0 8.2e-07 28.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 OAG43598.1 - 7.1e-09 34.6 0.1 1.6e-08 33.5 0.0 1.6 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OAG43598.1 - 2.1e-06 27.8 0.0 1.1e-05 25.5 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 OAG43598.1 - 0.02 14.0 0.0 0.084 11.9 0.0 1.9 1 1 0 1 1 1 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 OAG43598.1 - 0.081 12.9 0.8 0.58 10.1 0.0 2.6 3 0 0 3 3 3 0 FAD-NAD(P)-binding Ion_trans_2 PF07885.16 OAG43599.1 - 1.1e-25 89.3 21.6 8.5e-16 57.7 4.9 3.5 4 0 0 4 4 4 2 Ion channel DUF2070 PF09843.9 OAG43599.1 - 4 5.6 5.0 8.7 4.5 5.0 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Fungal_trans_2 PF11951.8 OAG43600.1 - 1.3e-07 30.8 0.6 6.4e-07 28.5 0.0 2.3 3 0 0 3 3 3 1 Fungal specific transcription factor domain LMBR1 PF04791.16 OAG43603.1 - 3.7e-119 398.9 3.9 4.2e-119 398.8 3.9 1.0 1 0 0 1 1 1 1 LMBR1-like membrane protein Holin_9 PF16936.5 OAG43603.1 - 0.093 12.9 4.8 0.072 13.3 1.4 2.3 2 0 0 2 2 2 0 Putative holin Filament PF00038.21 OAG43603.1 - 0.26 10.8 0.5 6.1 6.3 0.0 2.0 2 0 0 2 2 2 0 Intermediate filament protein KIX_2 PF16987.5 OAG43604.1 - 9.1e-12 44.8 0.0 9.1e-12 44.8 0.0 5.1 5 1 0 5 5 5 1 KIX domain adh_short PF00106.25 OAG43605.1 - 4.8e-34 117.5 0.0 7e-34 117.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG43605.1 - 5.4e-31 108.0 0.4 7.6e-31 107.5 0.4 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG43605.1 - 6.8e-06 26.1 0.0 0.00066 19.6 0.0 2.3 2 0 0 2 2 2 2 KR domain p450 PF00067.22 OAG43606.1 - 3.7e-49 167.7 0.0 5.7e-49 167.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.18 OAG43606.1 - 1.2e-14 54.0 0.1 2.3e-14 53.1 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG43606.1 - 1.2e-08 34.9 13.5 2.1e-08 34.1 13.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.22 OAG43607.1 - 6.7e-15 54.8 0.0 8e-15 54.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Abhydrolase_3 PF07859.13 OAG43608.1 - 2.4e-47 161.6 0.0 4e-47 160.8 0.0 1.3 2 0 0 2 2 2 1 alpha/beta hydrolase fold COesterase PF00135.28 OAG43608.1 - 1.2e-07 31.0 0.0 4.5e-07 29.1 0.0 1.7 1 1 0 1 1 1 1 Carboxylesterase family adh_short PF00106.25 OAG43609.1 - 8.7e-43 146.1 0.0 5e-25 88.1 0.0 2.0 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAG43609.1 - 2.5e-31 109.0 0.0 1.6e-18 67.1 0.0 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG43609.1 - 8.4e-06 25.8 0.0 0.0001 22.3 0.0 2.0 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 OAG43609.1 - 1.1e-05 25.0 0.0 4.4e-05 23.1 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 OAG43609.1 - 0.00049 20.0 0.0 0.0008 19.4 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 OAG43609.1 - 0.041 13.0 0.0 0.072 12.2 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain DUF1776 PF08643.10 OAG43609.1 - 0.052 12.9 0.0 0.071 12.5 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) AMP-binding PF00501.28 OAG43610.1 - 5e-08 31.9 0.0 1.7e-07 30.2 0.0 1.7 2 0 0 2 2 2 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG43610.1 - 0.0017 19.3 0.0 0.0035 18.3 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 OAG43611.1 - 2.2e-11 43.0 0.0 2.7e-11 42.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 OAG43611.1 - 6.5e-06 26.0 0.8 1e-05 25.3 0.8 1.3 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus Sugarporin_N PF11471.8 OAG43611.1 - 0.086 12.8 0.1 0.15 12.0 0.1 1.4 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension adh_short_C2 PF13561.6 OAG43612.1 - 9.9e-58 195.5 0.9 1.5e-57 194.9 0.9 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG43612.1 - 1.7e-56 190.8 1.4 2e-56 190.5 1.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG43612.1 - 2.1e-12 47.3 0.5 4.4e-12 46.3 0.3 1.5 1 1 0 1 1 1 1 KR domain DUF3360 PF11840.8 OAG43612.1 - 0.081 11.6 0.0 0.1 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3360) COG5 PF10392.9 OAG43612.1 - 0.17 12.1 0.0 0.32 11.2 0.0 1.4 1 0 0 1 1 1 0 Golgi transport complex subunit 5 FMO-like PF00743.19 OAG43613.1 - 1.2e-10 40.5 2.5 5.1e-08 31.8 2.4 3.1 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 OAG43613.1 - 0.00022 20.5 0.1 0.043 13.0 0.1 2.8 2 1 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_Gly3P_dh_N PF01210.23 OAG43613.1 - 0.14 12.1 0.1 1.1 9.2 0.0 2.3 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Fungal_trans PF04082.18 OAG43614.1 - 2.6e-24 85.7 0.2 5.2e-24 84.7 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain FMO-like PF00743.19 OAG43615.1 - 3.4e-14 52.2 0.1 1.9e-12 46.4 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OAG43615.1 - 1.6e-05 24.3 0.0 0.00064 19.1 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG43615.1 - 3.9e-05 22.9 0.0 0.00094 18.4 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 OAG43615.1 - 0.012 14.9 0.0 1.1 8.4 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Sugar_tr PF00083.24 OAG43616.1 - 4.3e-76 256.6 29.9 4.9e-76 256.4 29.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG43616.1 - 6.3e-26 91.1 32.2 6.3e-26 91.1 32.2 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_5 PF05631.14 OAG43616.1 - 1.3e-05 24.3 7.2 0.00018 20.5 3.1 2.3 2 0 0 2 2 2 2 Sugar-tranasporters, 12 TM TRI12 PF06609.13 OAG43616.1 - 0.11 10.9 18.2 0.024 13.1 2.0 2.1 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) Phage_holin_3_2 PF04550.12 OAG43616.1 - 0.28 11.7 3.4 1.4 9.5 3.4 2.2 1 0 0 1 1 1 0 Phage holin family 2 Fe-ADH PF00465.19 OAG43617.1 - 1.7e-60 204.7 0.0 2.2e-60 204.4 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 OAG43617.1 - 2.3e-06 27.5 0.2 0.027 14.2 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase PRTase_2 PF15609.6 OAG43617.1 - 0.16 11.5 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl transferase ADH_zinc_N PF00107.26 OAG43618.1 - 2.6e-07 30.7 0.0 5.4e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG43618.1 - 5.8e-05 22.9 0.0 0.00034 20.5 0.0 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Isochorismatase PF00857.20 OAG43619.1 - 3.4e-33 115.3 0.0 4.8e-33 114.8 0.0 1.2 1 0 0 1 1 1 1 Isochorismatase family Myb_DNA-binding PF00249.31 OAG43620.1 - 8e-08 32.4 0.1 1.7e-07 31.3 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OAG43620.1 - 0.037 14.3 0.1 0.088 13.1 0.1 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain HET PF06985.11 OAG43622.1 - 4.4e-28 98.5 0.1 1.2e-27 97.0 0.1 1.8 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SDH_alpha PF03313.15 OAG43624.1 - 1.8e-99 332.6 0.4 2.3e-99 332.3 0.4 1.1 1 0 0 1 1 1 1 Serine dehydratase alpha chain SDH_beta PF03315.15 OAG43624.1 - 5.2e-54 182.8 0.0 1.3e-53 181.5 0.0 1.7 1 0 0 1 1 1 1 Serine dehydratase beta chain NAD_binding_10 PF13460.6 OAG43626.1 - 5.3e-07 29.7 0.0 8.2e-07 29.1 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding HIM1 PF08732.10 OAG43626.1 - 1.7e-05 24.4 0.0 2.7e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 HIM1 Epimerase PF01370.21 OAG43626.1 - 8.1e-05 22.2 0.0 0.00032 20.2 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 OAG43626.1 - 0.003 17.2 0.1 0.003 17.2 0.1 1.9 2 1 0 2 2 2 1 NmrA-like family DUF1471 PF07338.13 OAG43626.1 - 0.019 15.0 0.0 0.041 13.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1471) FAD_binding_1 PF00667.20 OAG43627.1 - 6.5e-62 209.0 0.0 1.2e-61 208.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 OAG43627.1 - 2.1e-10 41.2 0.0 8.6e-10 39.2 0.0 2.0 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain POR PF01558.18 OAG43627.1 - 2.2e-09 37.6 0.1 6.6e-09 36.1 0.1 1.7 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase PFOR_II PF17147.4 OAG43627.1 - 5e-06 26.7 0.1 1.3e-05 25.4 0.1 1.7 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II Transketolase_C PF02780.20 OAG43627.1 - 0.00081 19.3 0.0 0.0029 17.5 0.0 1.9 1 0 0 1 1 1 1 Transketolase, C-terminal domain KH_1 PF00013.29 OAG43628.1 - 7.3e-89 291.6 30.0 4.5e-14 52.0 0.3 13.1 13 0 0 13 13 13 9 KH domain KH_2 PF07650.17 OAG43628.1 - 1.3e-12 47.3 19.7 0.067 13.0 0.3 7.5 6 1 1 7 7 7 5 KH domain SLS PF14611.6 OAG43628.1 - 1.7e-10 41.1 0.4 0.13 12.1 0.3 7.0 4 2 4 8 8 8 4 Mitochondrial inner-membrane-bound regulator KH_4 PF13083.6 OAG43628.1 - 5.9e-08 32.5 7.2 1.9 8.4 0.0 6.1 6 0 0 6 6 6 3 KH domain KH_5 PF13184.6 OAG43628.1 - 0.0097 16.0 11.5 23 5.1 0.0 6.9 7 0 0 7 7 7 1 NusA-like KH domain DUF1664 PF07889.12 OAG43628.1 - 0.013 15.5 1.3 4.7 7.3 0.2 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Glyco_hydro_20 PF00728.22 OAG43629.1 - 1.4e-75 255.0 0.0 1.7e-75 254.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 OAG43629.1 - 7.2e-22 78.5 0.0 1.5e-21 77.5 0.0 1.6 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 OAG43629.1 - 0.0055 17.5 0.0 0.06 14.1 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolase family 20, domain 2 p450 PF00067.22 OAG43630.1 - 2.9e-62 210.9 0.0 3.7e-62 210.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 zf-CCCH_2 PF14608.6 OAG43631.1 - 6.3e-12 45.5 61.9 1.5e-05 25.3 11.6 5.4 5 0 0 5 5 5 5 RNA-binding, Nab2-type zinc finger Nab2 PF11517.8 OAG43631.1 - 0.0014 18.9 0.0 0.0024 18.2 0.0 1.3 1 0 0 1 1 1 1 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) Pinin_SDK_N PF04697.13 OAG43631.1 - 0.16 12.6 8.2 0.24 12.0 3.2 2.5 2 0 0 2 2 2 0 pinin/SDK conserved region Pyridoxal_deC PF00282.19 OAG43632.1 - 6.6e-25 87.6 0.0 6.9e-17 61.2 0.0 2.9 2 1 0 2 2 2 2 Pyridoxal-dependent decarboxylase conserved domain Mon1 PF03164.14 OAG43633.1 - 1.4e-149 498.6 0.0 1.6e-149 498.4 0.0 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 Dopey_N PF04118.14 OAG43634.1 - 1.3e-98 329.9 0.0 4.6e-98 328.1 0.0 2.0 1 0 0 1 1 1 1 Dopey, N-terminal Cys_Met_Meta_PP PF01053.20 OAG43635.1 - 1.6e-27 96.1 0.0 2.3e-27 95.5 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 OAG43635.1 - 1.2e-09 37.8 0.0 2.3e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II HTH_6 PF01418.17 OAG43635.1 - 0.18 11.8 0.1 0.42 10.6 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family LSM PF01423.22 OAG43636.1 - 7.4e-16 57.6 0.0 9.5e-16 57.3 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 OAG43636.1 - 4.8e-05 23.4 0.1 7.6e-05 22.8 0.1 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain API5 PF05918.11 OAG43636.1 - 6.1 5.5 9.2 7.6 5.2 9.2 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Methyltransf_11 PF08241.12 OAG43637.1 - 2.1e-12 47.5 0.0 2.5e-11 44.1 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG43637.1 - 2.5e-12 47.3 0.0 6.5e-12 46.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG43637.1 - 5.1e-08 32.9 0.0 9.1e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAG43637.1 - 1.3e-07 31.6 0.0 2.2e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG43637.1 - 4e-07 30.7 0.0 1.3e-06 29.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain PTPRCAP PF15713.5 OAG43637.1 - 0.035 14.4 0.1 6.8 7.0 0.0 2.4 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated MTS PF05175.14 OAG43637.1 - 0.22 11.1 0.0 2.5 7.6 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase small domain Na_Ca_ex PF01699.24 OAG43639.1 - 3e-38 131.2 37.3 3e-21 76.0 16.0 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein AMP-binding PF00501.28 OAG43641.1 - 9.1e-55 185.9 0.1 1.1e-53 182.4 0.1 1.9 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG43641.1 - 6.9e-20 71.8 0.2 1.3e-19 71.0 0.2 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Abhydrolase_3 PF07859.13 OAG43642.1 - 4e-29 102.0 0.0 7.8e-29 101.0 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Fungal_trans PF04082.18 OAG43642.1 - 1.3e-22 80.1 1.5 3.2e-22 78.8 0.1 2.2 2 1 0 2 2 2 1 Fungal specific transcription factor domain FMO-like PF00743.19 OAG43643.1 - 7.9e-16 57.6 0.0 4.2e-15 55.2 0.0 1.9 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 OAG43643.1 - 3.9e-12 46.0 0.0 3.9e-11 42.7 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG43643.1 - 1.7e-11 44.0 0.0 6e-11 42.1 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG43643.1 - 7.4e-09 35.7 0.0 5.5e-08 32.9 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 OAG43643.1 - 3e-08 33.2 0.0 6.8e-07 28.8 0.0 2.5 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 OAG43643.1 - 0.00012 22.1 0.5 0.51 10.3 0.1 4.0 3 1 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.24 OAG43643.1 - 0.0011 18.6 0.1 0.7 9.4 0.1 2.6 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OAG43643.1 - 0.0035 16.5 0.0 0.0058 15.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 OAG43643.1 - 0.0054 16.0 0.4 0.015 14.6 0.4 1.7 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 OAG43643.1 - 0.0065 15.7 0.1 0.014 14.7 0.1 1.4 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 OAG43643.1 - 0.0071 15.5 0.1 0.61 9.1 0.1 2.8 3 0 0 3 3 3 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 OAG43643.1 - 0.011 15.2 0.0 0.028 13.8 0.0 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.14 OAG43643.1 - 0.035 12.8 0.5 0.071 11.8 0.2 1.6 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox PF00070.27 OAG43643.1 - 0.084 13.4 0.3 1.9 9.1 0.3 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Sugar_tr PF00083.24 OAG43644.1 - 6.5e-82 275.8 23.6 7.4e-82 275.6 23.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG43644.1 - 9.5e-33 113.6 37.3 1.9e-28 99.4 12.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 OAG43644.1 - 0.00034 19.2 2.1 0.00034 19.2 2.1 2.5 2 1 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) HEAT_EZ PF13513.6 OAG43645.1 - 4e-20 71.9 9.8 0.00022 21.7 0.1 10.3 10 2 2 12 12 12 5 HEAT-like repeat HEAT PF02985.22 OAG43645.1 - 3.3e-16 58.0 7.5 0.0074 16.5 0.0 9.4 10 0 0 10 10 9 3 HEAT repeat HEAT_2 PF13646.6 OAG43645.1 - 9.4e-15 54.8 9.5 0.0058 17.0 0.1 7.3 7 1 1 8 8 7 3 HEAT repeats IBN_N PF03810.19 OAG43645.1 - 4.1e-09 36.2 0.9 2.1e-08 34.0 0.9 2.4 1 0 0 1 1 1 1 Importin-beta N-terminal domain IFRD PF05004.13 OAG43645.1 - 4.6e-09 35.8 3.7 0.012 14.7 0.0 4.8 2 1 1 4 4 4 3 Interferon-related developmental regulator (IFRD) Cnd1 PF12717.7 OAG43645.1 - 1.9e-06 28.0 1.6 0.057 13.5 0.0 5.4 5 1 1 6 6 6 1 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 OAG43645.1 - 6.7e-06 26.6 0.0 4.2 8.0 0.0 6.6 6 1 1 7 7 6 1 Vacuolar 14 Fab1-binding region RTP1_C1 PF10363.9 OAG43645.1 - 7.7e-06 26.1 0.1 4.3 7.5 0.0 5.4 4 2 0 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 CLASP_N PF12348.8 OAG43645.1 - 3.6e-05 23.4 0.2 0.16 11.5 0.0 3.9 4 0 0 4 4 4 2 CLASP N terminal Adaptin_N PF01602.20 OAG43645.1 - 0.0004 19.1 0.5 0.62 8.5 0.0 3.3 2 1 0 3 3 3 2 Adaptin N terminal region Cohesin_HEAT PF12765.7 OAG43645.1 - 0.0013 18.9 0.1 0.75 10.2 0.0 3.8 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion MMS19_C PF12460.8 OAG43645.1 - 0.002 17.3 4.0 0.23 10.5 0.4 3.8 4 0 0 4 4 4 1 RNAPII transcription regulator C-terminal Tti2 PF10521.9 OAG43645.1 - 0.0059 16.2 0.0 12 5.3 0.0 4.6 4 1 1 5 5 5 0 Tti2 family Arm PF00514.23 OAG43645.1 - 0.009 16.0 8.3 2.6 8.2 0.0 6.3 7 0 0 7 7 7 1 Armadillo/beta-catenin-like repeat API5 PF05918.11 OAG43645.1 - 0.016 14.1 1.2 0.058 12.2 0.0 2.3 2 0 0 2 2 2 0 Apoptosis inhibitory protein 5 (API5) CbeA_antitoxin PF06154.11 OAG43645.1 - 0.06 13.9 0.1 15 6.2 0.0 3.1 3 0 0 3 3 2 0 CbeA_antitoxin, type IV, cytoskeleton bundling-enhancing factor A Zn_clus PF00172.18 OAG43646.1 - 0.0097 16.0 12.3 0.025 14.7 3.7 2.4 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Zwint PF15556.6 OAG43646.1 - 0.015 14.8 0.1 0.02 14.4 0.1 1.2 1 0 0 1 1 1 0 ZW10 interactor DUF1989 PF09347.10 OAG43647.1 - 3.7e-41 140.5 0.0 4.7e-41 140.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) Sugar_tr PF00083.24 OAG43648.1 - 5.4e-83 279.3 23.0 6.2e-83 279.1 23.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG43648.1 - 3.6e-25 88.6 35.7 5.7e-22 78.1 20.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4181 PF13789.6 OAG43648.1 - 0.088 13.1 2.0 0.23 11.7 2.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4181) FixQ PF05545.11 OAG43648.1 - 5.8 7.0 7.9 0.35 10.9 1.3 2.5 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ ABM PF03992.16 OAG43649.1 - 0.00098 19.2 0.0 0.0016 18.5 0.0 1.4 1 1 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Cupin_2 PF07883.11 OAG43650.1 - 2.8e-10 39.7 0.4 4.5e-10 39.1 0.4 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.7 OAG43650.1 - 0.00044 20.0 0.4 0.00056 19.7 0.4 1.2 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.19 OAG43650.1 - 0.0034 17.3 0.4 0.0046 16.8 0.4 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_3 PF05899.12 OAG43650.1 - 0.012 15.3 0.1 0.028 14.1 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF861) Metallophos PF00149.28 OAG43651.1 - 1.1e-11 45.6 4.1 2.1e-11 44.7 4.1 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OAG43651.1 - 8.3e-10 39.1 0.0 1.8e-07 31.5 0.0 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain PEPCK_ATP PF01293.20 OAG43653.1 - 1.4e-216 719.6 0.0 1.7e-216 719.4 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_16 PF13191.6 OAG43653.1 - 0.067 13.6 0.0 0.13 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain HCMVantigenic_N PF12154.8 OAG43653.1 - 0.12 12.5 0.5 0.33 11.1 0.5 1.8 1 0 0 1 1 1 0 Glycoprotein B N-terminal antigenic domain of HCMV AAA_33 PF13671.6 OAG43653.1 - 0.17 12.0 0.0 0.33 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain PEX11 PF05648.14 OAG43654.1 - 7e-67 225.2 0.7 7.8e-67 225.0 0.7 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) YorP PF09629.10 OAG43654.1 - 0.12 12.6 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 YorP protein AMP-binding PF00501.28 OAG43655.1 - 1.3e-96 323.8 0.0 1.6e-96 323.6 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG43655.1 - 1e-14 55.2 0.1 2.3e-14 54.1 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF4350 PF14258.6 OAG43655.1 - 0.15 12.5 0.0 0.53 10.8 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4350) Sugar_tr PF00083.24 OAG43656.1 - 7.9e-39 133.8 24.3 5.7e-24 84.8 5.9 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 OAG43656.1 - 5e-22 78.3 30.6 1.2e-13 50.8 19.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PEMT PF04191.13 OAG43656.1 - 0.036 14.5 1.7 0.2 12.1 0.1 2.9 3 0 0 3 3 3 0 Phospholipid methyltransferase Transgly_assoc PF04226.13 OAG43656.1 - 1.8 8.9 16.3 1.5 9.1 0.1 4.9 3 1 1 4 4 4 0 Transglycosylase associated protein RPN7 PF10602.9 OAG43657.1 - 4.8e-57 192.4 0.4 9.2e-57 191.5 0.4 1.5 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 OAG43657.1 - 2.5e-15 56.8 0.0 5.6e-15 55.7 0.0 1.6 1 0 0 1 1 1 1 PCI domain Aminotran_1_2 PF00155.21 OAG43658.1 - 8.8e-34 117.2 0.0 1.2e-33 116.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Abhydrolase_1 PF00561.20 OAG43659.1 - 4.6e-18 65.8 0.0 3.5e-17 62.9 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.18 OAG43659.1 - 4.3e-12 46.1 0.0 7.9e-11 41.9 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 OAG43659.1 - 6.4e-11 42.0 0.0 2.8e-10 39.9 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OAG43659.1 - 1.9e-10 41.7 0.2 2.8e-10 41.2 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 OAG43659.1 - 2.9e-08 33.5 0.1 1e-07 31.6 0.0 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family BAAT_C PF08840.11 OAG43659.1 - 6.3e-07 29.5 0.1 3.4e-06 27.1 0.0 1.9 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal FSH1 PF03959.13 OAG43659.1 - 2.3e-06 27.4 0.0 1.9e-05 24.4 0.0 2.1 1 1 0 1 1 1 1 Serine hydrolase (FSH1) PGAP1 PF07819.13 OAG43659.1 - 0.00086 19.1 0.0 0.0019 17.9 0.0 1.5 1 1 0 1 1 1 1 PGAP1-like protein Peptidase_S15 PF02129.18 OAG43659.1 - 0.0053 16.4 0.0 0.027 14.1 0.0 1.9 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_3 PF07859.13 OAG43659.1 - 0.017 15.0 0.0 0.23 11.3 0.0 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold Esterase PF00756.20 OAG43659.1 - 0.048 13.3 0.0 0.057 13.1 0.0 1.4 1 1 0 1 1 1 0 Putative esterase Abhydrolase_2 PF02230.16 OAG43659.1 - 0.058 13.2 0.5 8.9 6.0 0.1 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase DUF2048 PF09752.9 OAG43659.1 - 0.14 11.2 0.1 0.65 9.0 0.1 1.8 2 0 0 2 2 2 0 Abhydrolase domain containing 18 adh_short PF00106.25 OAG43660.1 - 7.2e-28 97.4 0.1 1e-27 96.9 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG43660.1 - 2.3e-21 76.4 0.2 7.4e-21 74.8 0.2 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG43660.1 - 1.4e-06 28.4 0.5 7e-06 26.1 0.1 1.9 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 OAG43660.1 - 0.022 13.9 0.0 0.037 13.1 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein VD10_N PF08476.10 OAG43660.1 - 0.064 12.9 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Viral D10 N-terminal Shikimate_DH PF01488.20 OAG43660.1 - 0.1 12.6 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase adh_short PF00106.25 OAG43661.1 - 4.9e-28 97.9 0.0 9.2e-28 97.0 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG43661.1 - 3.5e-20 72.6 0.0 2.2e-19 69.9 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG43661.1 - 0.0026 17.7 0.1 0.01 15.8 0.1 2.1 1 1 0 1 1 1 1 KR domain Fungal_trans PF04082.18 OAG43662.1 - 1.9e-25 89.4 0.5 3.6e-25 88.5 0.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short_C2 PF13561.6 OAG43663.1 - 1.4e-64 217.9 4.1 1.5e-64 217.7 4.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG43663.1 - 2.2e-47 161.1 0.9 2.6e-47 160.8 0.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG43663.1 - 6.1e-08 32.8 1.0 1e-07 32.0 0.8 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG43663.1 - 0.04 13.4 1.2 0.36 10.3 0.9 2.2 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Ldh_1_N PF00056.23 OAG43663.1 - 0.046 13.8 0.3 0.074 13.1 0.3 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 OAG43663.1 - 0.061 12.6 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Glug PF07581.12 OAG43663.1 - 0.28 11.7 0.3 0.28 11.7 0.3 2.7 3 0 0 3 3 3 0 The GLUG motif Sugar_tr PF00083.24 OAG43664.1 - 5.4e-77 259.6 19.5 6.7e-77 259.3 19.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG43664.1 - 8.7e-28 97.2 32.3 1.3e-26 93.4 16.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily FTA2 PF13095.6 OAG43665.1 - 1.9e-06 27.7 0.0 7.6e-06 25.7 0.0 1.9 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 TPR_12 PF13424.6 OAG43666.1 - 1.3e-62 208.1 33.8 6.8e-19 67.9 0.4 4.8 1 1 4 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.6 OAG43666.1 - 2.8e-50 166.9 8.9 3.6e-14 52.1 0.0 5.8 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_7 PF13176.6 OAG43666.1 - 1.8e-18 65.1 8.3 0.00018 21.3 0.1 5.0 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.28 OAG43666.1 - 8.1e-15 53.9 6.9 9.9e-05 22.0 0.0 5.1 5 0 0 5 5 4 4 Tetratricopeptide repeat TPR_8 PF13181.6 OAG43666.1 - 2.4e-11 42.9 7.3 0.024 14.8 0.0 5.8 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 OAG43666.1 - 4.1e-11 42.1 12.4 0.0075 16.3 0.1 5.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 OAG43666.1 - 2.6e-09 37.1 12.4 0.24 12.3 0.1 7.1 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 OAG43666.1 - 2.6e-07 31.2 15.3 0.17 12.5 0.1 5.1 1 1 4 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.6 OAG43666.1 - 3.9e-07 30.0 0.1 4 8.0 0.0 4.9 4 0 0 4 4 4 1 Tetratricopeptide repeat NACHT PF05729.12 OAG43666.1 - 4.2e-07 30.0 0.0 8.5e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 NACHT domain DUF676 PF05057.14 OAG43666.1 - 4.7e-07 29.5 0.0 9.3e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 OAG43666.1 - 2.4e-06 28.3 1.6 0.00049 20.8 0.0 2.7 2 1 0 2 2 2 1 Alpha/beta hydrolase family NB-ARC PF00931.22 OAG43666.1 - 4.3e-06 26.1 0.0 0.01 15.0 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain TPR_4 PF07721.14 OAG43666.1 - 6.9e-06 26.2 8.5 0.94 10.3 0.1 6.2 6 0 0 6 6 5 2 Tetratricopeptide repeat MIT PF04212.18 OAG43666.1 - 1.3e-05 25.2 0.6 0.14 12.3 0.1 3.6 3 0 0 3 3 3 2 MIT (microtubule interacting and transport) domain ANAPC3 PF12895.7 OAG43666.1 - 1.4e-05 25.3 0.8 2.7 8.3 0.0 4.3 1 1 3 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 OAG43666.1 - 5.1e-05 22.8 10.3 0.00054 19.4 0.4 3.1 2 1 1 3 3 3 2 MalT-like TPR region AAA_22 PF13401.6 OAG43666.1 - 0.00019 21.7 0.0 0.00092 19.5 0.0 2.2 2 0 0 2 2 1 1 AAA domain TPR_19 PF14559.6 OAG43666.1 - 0.0025 18.3 9.2 0.84 10.2 0.3 4.0 1 1 3 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 OAG43666.1 - 0.0033 18.0 8.3 2.6 8.9 0.7 5.0 5 0 0 5 5 4 1 Tetratricopeptide repeat PPR PF01535.20 OAG43666.1 - 0.018 15.3 0.2 32 5.1 0.0 4.0 4 0 0 4 4 3 0 PPR repeat PGAP1 PF07819.13 OAG43666.1 - 0.02 14.6 0.0 0.041 13.6 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein TPR_3 PF07720.12 OAG43666.1 - 0.024 14.6 10.5 3.1 7.9 0.9 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_20 PF14561.6 OAG43666.1 - 0.029 14.7 1.1 11 6.5 0.0 4.6 4 2 2 6 6 5 0 Tetratricopeptide repeat Hydrolase_4 PF12146.8 OAG43666.1 - 0.03 13.6 0.0 0.072 12.3 0.0 1.7 1 0 0 1 1 1 0 Serine aminopeptidase, S33 AAA_16 PF13191.6 OAG43666.1 - 0.064 13.6 0.1 0.34 11.3 0.1 2.5 1 1 0 1 1 1 0 AAA ATPase domain ResIII PF04851.15 OAG43666.1 - 0.079 13.0 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_25 PF13481.6 OAG43666.1 - 0.097 12.2 0.0 0.92 9.0 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA_7 PF12775.7 OAG43666.1 - 0.15 11.6 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region TPR_11 PF13414.6 OAG43666.1 - 0.5 10.1 11.9 0.42 10.3 0.1 4.9 6 0 0 6 6 6 0 TPR repeat TPR_5 PF12688.7 OAG43666.1 - 2.5 8.3 6.3 4.6 7.5 1.4 3.6 2 1 1 3 3 3 0 Tetratrico peptide repeat DUF5061 PF16587.5 OAG43667.1 - 0.11 12.6 1.1 1.2 9.2 0.0 2.7 2 1 1 3 3 3 0 17 kDa common-antigen outer membrane protein CBM_4_9 PF02018.17 OAG43668.1 - 0.031 14.5 0.0 0.058 13.7 0.0 1.4 1 0 0 1 1 1 0 Carbohydrate binding domain AMP-binding PF00501.28 OAG43669.1 - 2.9e-49 167.8 0.0 4.1e-49 167.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 OAG43669.1 - 0.00096 19.0 0.1 0.015 15.2 0.0 3.1 3 0 0 3 3 3 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 OAG43669.1 - 0.0053 17.7 0.0 0.018 16.0 0.0 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DUF3318 PF11780.8 OAG43669.1 - 0.039 13.9 0.0 0.071 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3318) Fungal_trans PF04082.18 OAG43670.1 - 8.9e-11 41.3 0.5 2.4e-10 39.9 0.2 1.6 1 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG43670.1 - 3.4e-07 30.3 10.1 5.9e-07 29.5 10.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ACP_syn_III PF08545.10 OAG43670.1 - 0.14 12.1 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III AidB_N PF18158.1 OAG43671.1 - 1.3e-12 47.9 0.0 2.9e-12 46.8 0.0 1.6 1 0 0 1 1 1 1 Adaptive response protein AidB N-terminal domain Acyl-CoA_dh_1 PF00441.24 OAG43671.1 - 8.6e-12 45.5 0.5 3.9e-11 43.4 0.5 2.0 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 OAG43671.1 - 3.6e-11 43.1 0.1 1.5e-10 41.1 0.1 2.0 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain DUF3000 PF11452.8 OAG43671.1 - 0.039 13.5 0.1 0.093 12.2 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3000) Acyl-CoA_dh_M PF02770.19 OAG43672.1 - 4.9e-11 42.7 0.0 1.1e-10 41.6 0.0 1.6 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 OAG43672.1 - 5.8e-10 39.6 0.0 1.9e-09 37.9 0.0 1.8 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain AidB_N PF18158.1 OAG43672.1 - 2.2e-08 34.2 0.0 4.9e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Adaptive response protein AidB N-terminal domain ECH_1 PF00378.20 OAG43674.1 - 9e-27 94.0 0.0 2.6e-20 72.8 0.0 2.1 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAG43674.1 - 4.5e-20 72.4 0.0 1.5e-18 67.4 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase NTS_2 PF15448.6 OAG43674.1 - 0.04 14.3 0.0 0.083 13.3 0.0 1.4 1 0 0 1 1 1 0 N-terminal segments of P. falciparum erythrocyte membrane protein zf-C2H2 PF00096.26 OAG43675.1 - 5.6e-06 26.5 11.7 0.00017 21.9 2.9 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OAG43675.1 - 8.3e-05 22.8 2.1 8.3e-05 22.8 2.1 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-met PF12874.7 OAG43675.1 - 8.5e-05 22.8 8.8 0.0011 19.2 0.9 2.6 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 OAG43675.1 - 0.001 19.7 1.5 0.001 19.7 1.5 2.7 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OAG43675.1 - 0.0052 17.0 1.5 0.017 15.4 1.5 1.8 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 OAG43675.1 - 0.042 14.1 4.3 0.074 13.4 4.3 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding FAD_binding_3 PF01494.19 OAG43679.1 - 5.7e-21 75.1 0.2 2.3e-20 73.2 0.2 1.8 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 OAG43679.1 - 1.9e-08 33.9 0.7 5.4e-07 29.1 0.7 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG43679.1 - 4.4e-06 26.8 1.5 1.2e-05 25.4 0.8 2.2 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 OAG43679.1 - 1.4e-05 24.3 1.3 3.2e-05 23.2 1.3 1.5 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 OAG43679.1 - 1.9e-05 23.9 1.3 2.1e-05 23.7 0.1 1.7 2 1 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.24 OAG43679.1 - 1.9e-05 24.4 6.4 7.4e-05 22.5 3.5 2.4 3 0 0 3 3 3 1 FAD dependent oxidoreductase HI0933_like PF03486.14 OAG43679.1 - 6.1e-05 21.9 0.6 0.0048 15.6 0.4 2.1 2 0 0 2 2 2 1 HI0933-like protein Trp_halogenase PF04820.14 OAG43679.1 - 0.00018 20.5 0.7 0.019 13.9 0.2 2.6 2 1 1 3 3 3 1 Tryptophan halogenase Pyr_redox PF00070.27 OAG43679.1 - 0.0002 21.8 1.4 0.0012 19.4 2.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 OAG43679.1 - 0.0043 16.9 0.1 0.0079 16.1 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Amino_oxidase PF01593.24 OAG43679.1 - 0.0086 15.4 2.4 0.3 10.3 0.4 2.5 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase GAT PF03127.14 OAG43679.1 - 0.06 13.6 0.0 2.7 8.3 0.0 2.5 2 0 0 2 2 2 0 GAT domain NAD_binding_9 PF13454.6 OAG43679.1 - 0.067 13.2 2.1 6.9 6.6 0.2 2.9 3 1 1 4 4 4 0 FAD-NAD(P)-binding Thi4 PF01946.17 OAG43679.1 - 0.073 12.3 0.5 0.11 11.7 0.5 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 OAG43679.1 - 0.13 11.5 0.1 0.35 10.1 0.1 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OAG43679.1 - 0.26 10.3 3.0 0.28 10.2 2.2 1.4 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_oxidored PF12831.7 OAG43679.1 - 7.1 5.9 5.9 1.5 8.1 1.1 2.2 2 1 1 3 3 3 0 FAD dependent oxidoreductase bZIP_1 PF00170.21 OAG43680.1 - 0.00039 20.4 16.0 0.017 15.2 16.0 2.3 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 OAG43680.1 - 0.00093 19.2 15.7 0.0088 16.1 14.0 2.2 1 1 1 2 2 2 2 Basic region leucine zipper bZIP_Maf PF03131.17 OAG43680.1 - 0.07 13.6 14.1 0.13 12.8 14.1 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor Methyltransf_23 PF13489.6 OAG43681.1 - 4.8e-14 52.5 0.0 6.7e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG43681.1 - 3.7e-09 37.1 0.0 2.2e-08 34.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG43681.1 - 8.7e-07 29.6 0.0 1.8e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG43681.1 - 2.4e-06 28.2 0.0 0.00014 22.5 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG43681.1 - 3.3e-06 27.0 0.0 5.5e-06 26.3 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain DREV PF05219.12 OAG43681.1 - 0.17 11.0 0.0 3.8 6.5 0.0 2.1 2 0 0 2 2 2 0 DREV methyltransferase SLAC1 PF03595.17 OAG43682.1 - 1.6e-97 326.7 56.5 1.8e-97 326.5 56.5 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel DUF3481 PF11980.8 OAG43682.1 - 0.11 12.2 0.0 0.89 9.3 0.0 2.2 2 0 0 2 2 2 0 C-terminal domain of neuropilin glycoprotein Oxidored_molyb PF00174.19 OAG43683.1 - 5.3e-57 192.2 0.1 1.3e-56 190.9 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 OAG43683.1 - 9.3e-23 80.8 0.3 2.3e-22 79.5 0.3 1.7 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Cyt-b5 PF00173.28 OAG43683.1 - 4.5e-13 49.1 0.0 1e-12 48.0 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Amidase PF01425.21 OAG43684.1 - 6.6e-81 272.6 0.0 8.6e-81 272.2 0.0 1.1 1 0 0 1 1 1 1 Amidase HARP PF07443.13 OAG43684.1 - 0.096 12.3 0.1 3.1 7.5 0.0 2.5 2 0 0 2 2 2 0 HepA-related protein (HARP) Zn_clus PF00172.18 OAG43685.1 - 3.5e-05 23.8 14.0 6e-05 23.1 14.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1556 PF07590.11 OAG43685.1 - 0.061 13.6 1.1 0.061 13.6 1.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1556) Rpp20 PF12328.8 OAG43687.1 - 7.2e-30 103.7 6.7 6e-29 100.8 6.7 2.2 1 1 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.21 OAG43687.1 - 2.4e-11 43.3 0.0 4.5e-11 42.4 0.0 1.5 1 1 0 1 1 1 1 Alba FXR_C1 PF16096.5 OAG43687.1 - 0.013 15.7 1.4 0.029 14.6 1.4 1.6 1 0 0 1 1 1 0 Fragile X-related 1 protein C-terminal region 2 Pneumo_att_G PF05539.11 OAG43687.1 - 0.087 12.4 0.7 0.12 11.9 0.7 1.2 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Sigma70_ner PF04546.13 OAG43687.1 - 0.74 9.7 7.1 0.37 10.7 4.8 1.7 2 0 0 2 2 2 0 Sigma-70, non-essential region Metallophos_2 PF12850.7 OAG43688.1 - 1.8e-12 47.8 0.0 2.2e-12 47.5 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain TFIIF_beta PF02270.15 OAG43690.1 - 8.9e-27 93.0 0.5 1.5e-26 92.3 0.5 1.4 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain TFIIF_beta_N PF17683.1 OAG43690.1 - 1.5e-23 84.0 0.3 4.9e-23 82.3 0.0 1.9 2 0 0 2 2 2 1 TFIIF, beta subunit N-terminus Tau95 PF09734.9 OAG43690.1 - 0.00017 22.4 0.8 0.00035 21.4 0.8 1.7 1 1 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain CTP_transf_like PF01467.26 OAG43692.1 - 2.1e-24 86.3 0.0 3.5e-22 79.2 0.0 2.3 2 0 0 2 2 2 2 Cytidylyltransferase-like Glutaredoxin PF00462.24 OAG43694.1 - 8.3e-10 38.7 0.1 2.9e-08 33.8 0.1 2.7 1 1 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.6 OAG43694.1 - 0.0075 16.7 0.1 0.072 13.5 0.1 2.2 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain zf-U1 PF06220.12 OAG43697.1 - 1.5e-10 40.6 0.6 3.1e-10 39.6 0.6 1.5 1 0 0 1 1 1 1 U1 zinc finger PRELI PF04707.14 OAG43698.1 - 2.9e-44 150.7 0.4 3.3e-44 150.5 0.4 1.0 1 0 0 1 1 1 1 PRELI-like family GATase_3 PF07685.14 OAG43698.1 - 0.082 12.5 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain Abhydrolase_6 PF12697.7 OAG43699.1 - 2.8e-09 37.9 5.7 3.7e-07 31.0 5.7 2.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAG43699.1 - 9.9e-09 35.2 0.0 3.8e-08 33.3 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAG43699.1 - 0.0019 17.5 0.0 0.011 15.0 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 GST_N_3 PF13417.6 OAG43701.1 - 2.4e-15 56.7 0.0 4.2e-15 55.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OAG43701.1 - 6.8e-14 51.9 0.0 1.1e-13 51.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 OAG43701.1 - 8.9e-10 38.8 0.0 1.4e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAG43701.1 - 1.5e-07 31.4 0.1 2.8e-07 30.4 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 OAG43701.1 - 8.4e-05 23.1 0.0 0.00015 22.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OAG43701.1 - 0.027 14.7 0.0 0.069 13.3 0.0 1.6 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Pkinase PF00069.25 OAG43704.1 - 6.9e-56 189.5 0.1 1e-39 136.5 0.2 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAG43704.1 - 2.4e-26 92.6 0.2 1.3e-19 70.5 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 OAG43704.1 - 2.4e-06 26.7 0.1 3.6e-06 26.2 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OAG43704.1 - 0.00039 20.4 0.1 0.062 13.2 0.2 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 OAG43704.1 - 0.00058 19.3 0.0 0.0017 17.7 0.0 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OAG43704.1 - 0.0012 18.2 0.2 0.0045 16.4 0.0 1.9 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 OAG43704.1 - 0.031 13.9 0.2 7.2 6.2 0.0 2.5 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Seadorna_VP7 PF07387.11 OAG43704.1 - 0.031 13.3 0.0 0.05 12.6 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.22 OAG43704.1 - 0.042 13.4 1.3 1.2 8.6 0.0 2.3 2 0 0 2 2 2 0 RIO1 family PA28_alpha PF02251.18 OAG43704.1 - 0.067 13.2 0.2 0.84 9.7 0.0 2.7 3 0 0 3 3 3 0 Proteasome activator pa28 alpha subunit SpoIIIAH PF12685.7 OAG43704.1 - 0.39 10.5 3.7 0.7 9.7 3.7 1.4 1 0 0 1 1 1 0 SpoIIIAH-like protein TFIIA PF03153.13 OAG43704.1 - 5.4 6.9 16.1 9 6.2 16.1 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Tim54 PF11711.8 OAG43705.1 - 1.5e-144 481.4 0.6 1.8e-144 481.2 0.6 1.1 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 CAP_GLY PF01302.25 OAG43706.1 - 3.3e-16 59.1 0.0 6.5e-16 58.1 0.0 1.4 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.7 OAG43706.1 - 2.1e-09 37.5 7.6 1.7e-05 25.1 1.2 5.3 3 1 3 7 7 7 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 OAG43706.1 - 1e-06 28.4 0.8 0.016 14.7 0.1 3.1 3 1 0 3 3 3 2 Leucine-rich repeat LRR_6 PF13516.6 OAG43706.1 - 1.8e-05 24.4 5.0 4.9 7.5 0.1 6.0 6 0 0 6 6 6 1 Leucine Rich repeat LRR_8 PF13855.6 OAG43706.1 - 0.00041 20.0 12.4 0.035 13.9 4.2 4.2 1 1 2 3 3 3 3 Leucine rich repeat LRR_1 PF00560.33 OAG43706.1 - 0.042 14.4 9.1 22 6.1 0.8 6.2 5 2 0 5 5 5 0 Leucine Rich Repeat Dna2 PF08696.11 OAG43707.1 - 1.1e-62 211.5 0.0 2.8e-62 210.2 0.0 1.7 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_12 PF13087.6 OAG43707.1 - 1.8e-48 164.8 0.0 3.4e-48 163.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 OAG43707.1 - 1.7e-30 106.7 5.4 6.6e-16 58.9 0.0 3.3 2 1 1 3 3 3 2 AAA domain AAA_30 PF13604.6 OAG43707.1 - 7e-16 58.5 0.0 1.3e-15 57.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OAG43707.1 - 1.7e-12 47.9 0.5 4.7e-12 46.5 0.0 2.1 2 0 0 2 2 1 1 AAA domain Cas_Cas4 PF01930.17 OAG43707.1 - 9.6e-08 32.3 4.5 1e-07 32.2 1.1 2.5 3 0 0 3 3 3 1 Domain of unknown function DUF83 Viral_helicase1 PF01443.18 OAG43707.1 - 1.3e-05 25.1 5.0 0.37 10.5 0.1 4.0 3 1 1 4 4 4 2 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.21 OAG43707.1 - 0.00022 20.8 0.2 0.0008 19.0 0.0 2.0 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain SRP54 PF00448.22 OAG43707.1 - 0.00049 19.8 0.0 0.001 18.7 0.0 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain Helicase_RecD PF05127.14 OAG43707.1 - 0.0005 20.0 0.0 0.0018 18.2 0.0 2.0 1 0 0 1 1 1 1 Helicase AAA_16 PF13191.6 OAG43707.1 - 0.0031 17.9 0.0 0.022 15.1 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain CbiA PF01656.23 OAG43707.1 - 0.01 15.9 0.0 0.023 14.8 0.0 1.6 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ResIII PF04851.15 OAG43707.1 - 0.016 15.2 0.0 0.056 13.5 0.0 2.0 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_7 PF12775.7 OAG43707.1 - 0.027 14.0 0.1 0.069 12.7 0.1 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF87 PF01935.17 OAG43707.1 - 0.029 14.5 0.8 0.15 12.1 0.2 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain PIF1 PF05970.14 OAG43707.1 - 0.035 13.3 2.1 0.15 11.2 0.3 2.6 2 1 0 2 2 2 0 PIF1-like helicase cobW PF02492.19 OAG43707.1 - 0.061 12.9 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.15 OAG43707.1 - 0.085 12.8 0.2 0.26 11.2 0.2 1.8 1 0 0 1 1 1 0 NTPase AAA_25 PF13481.6 OAG43707.1 - 0.093 12.3 0.0 0.39 10.3 0.0 2.0 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 OAG43707.1 - 0.14 11.1 0.0 0.26 10.2 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA PF00004.29 OAG43707.1 - 0.15 12.5 0.3 0.44 11.0 0.0 2.0 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 OAG43707.1 - 0.15 11.8 0.1 0.32 10.7 0.1 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Ribosomal_S7 PF00177.21 OAG43707.1 - 0.21 11.2 0.7 4.2 7.0 0.0 2.9 3 0 0 3 3 3 0 Ribosomal protein S7p/S5e SIR2 PF02146.17 OAG43708.1 - 3.1e-43 147.8 0.0 2.2e-31 109.1 0.0 2.4 2 0 0 2 2 2 2 Sir2 family DUF592 PF04574.13 OAG43708.1 - 0.00039 20.2 0.0 0.0007 19.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.22 OAG43708.1 - 0.027 14.2 0.0 4.3 7.1 0.0 2.3 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Mito_carr PF00153.27 OAG43709.1 - 4.1e-62 206.1 0.5 2.2e-19 69.2 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein HLH PF00010.26 OAG43710.1 - 1.7e-11 43.9 0.0 8.2e-11 41.7 0.0 2.0 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain Ank_5 PF13857.6 OAG43711.1 - 3.5e-11 43.1 0.6 4.8e-09 36.3 0.1 2.8 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 OAG43711.1 - 1.2e-06 29.0 0.5 3e-06 27.7 0.4 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAG43711.1 - 1.3e-06 28.8 0.2 2.2e-05 24.9 0.1 2.5 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG43711.1 - 4.5e-05 23.5 1.3 0.00034 20.8 0.1 3.0 3 1 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 OAG43711.1 - 0.00039 20.7 0.2 0.0092 16.4 0.1 2.5 2 0 0 2 2 2 1 Ankyrin repeat RNA_lig_T4_1 PF09511.10 OAG43712.1 - 3.8e-87 291.8 0.0 7.4e-87 290.8 0.0 1.5 1 0 0 1 1 1 1 RNA ligase tRNA_lig_CPD PF08302.11 OAG43712.1 - 3e-80 269.3 0.0 5.1e-80 268.6 0.0 1.4 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain tRNA_lig_kinase PF08303.11 OAG43712.1 - 5e-48 163.4 0.1 8.8e-48 162.6 0.1 1.4 1 0 0 1 1 1 1 tRNA ligase kinase domain AAA_18 PF13238.6 OAG43712.1 - 0.00075 20.1 0.0 0.022 15.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain RNA_ligase PF09414.10 OAG43712.1 - 0.0077 16.6 0.0 0.017 15.5 0.0 1.6 1 0 0 1 1 1 1 RNA ligase Virulence_fact PF13769.6 OAG43712.1 - 0.097 12.9 0.3 0.36 11.1 0.3 2.1 1 0 0 1 1 1 0 Virulence factor Cyclin_N PF00134.23 OAG43713.1 - 3.8e-47 159.2 0.0 7.4e-45 151.8 0.0 2.2 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 OAG43713.1 - 4e-33 114.0 0.1 8.1e-33 113.0 0.1 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain DUF5132 PF17195.4 OAG43713.1 - 0.69 10.1 3.1 1.5 9.0 3.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF5132) HIT PF01230.23 OAG43714.1 - 1.5e-19 70.5 0.1 2.4e-19 69.9 0.1 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 OAG43714.1 - 1.1e-05 25.8 0.1 3.2e-05 24.4 0.0 1.7 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 OAG43714.1 - 0.14 12.0 0.0 0.34 10.8 0.0 1.7 1 1 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 UPF0020 PF01170.18 OAG43715.1 - 1.6e-08 34.5 0.0 0.00023 20.9 0.0 2.2 2 0 0 2 2 2 2 Putative RNA methylase family UPF0020 N6_N4_Mtase PF01555.18 OAG43715.1 - 0.00083 19.1 0.0 0.0061 16.3 0.0 2.2 2 0 0 2 2 2 1 DNA methylase RWD PF05773.22 OAG43716.1 - 8.2e-22 77.7 0.0 1.7e-21 76.7 0.0 1.5 1 0 0 1 1 1 1 RWD domain AP3D1 PF06375.11 OAG43716.1 - 0.076 13.2 5.2 0.12 12.6 5.2 1.3 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 MPM1 PF17234.2 OAG43716.1 - 0.16 12.2 3.7 0.23 11.7 3.7 1.2 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 Mpp10 PF04006.12 OAG43717.1 - 9e-107 358.0 48.3 3.1e-106 356.2 48.3 1.8 1 1 0 1 1 1 1 Mpp10 protein FliE PF02049.18 OAG43717.1 - 0.019 15.1 0.2 0.072 13.2 0.2 2.1 1 0 0 1 1 1 0 Flagellar hook-basal body complex protein FliE SPX PF03105.19 OAG43718.1 - 1e-08 35.5 22.4 0.0027 17.7 0.4 4.6 2 2 2 4 4 4 3 SPX domain VTC PF09359.10 OAG43718.1 - 0.0011 18.4 0.0 2 7.7 0.1 2.8 1 1 0 2 2 2 2 VTC domain Sulfate_transp PF00916.20 OAG43719.1 - 9.1e-63 212.3 19.0 1.4e-62 211.6 19.0 1.2 1 0 0 1 1 1 1 Sulfate permease family cNMP_binding PF00027.29 OAG43719.1 - 2.3e-13 50.0 0.0 4.3e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.21 OAG43719.1 - 6.1e-13 48.4 0.1 1.1e-12 47.6 0.1 1.4 1 0 0 1 1 1 1 STAS domain Dicty_CAR PF05462.11 OAG43719.1 - 0.063 12.4 2.1 0.051 12.7 0.3 1.6 2 0 0 2 2 2 0 Slime mold cyclic AMP receptor PH_6 PF15406.6 OAG43720.1 - 5.8e-33 113.5 3.5 5.8e-33 113.5 3.5 3.2 3 0 0 3 3 3 1 Pleckstrin homology domain PH PF00169.29 OAG43720.1 - 7.5e-05 23.2 0.4 0.001 19.6 0.1 2.7 2 1 0 2 2 2 1 PH domain PH_8 PF15409.6 OAG43720.1 - 0.11 12.8 0.0 0.21 11.9 0.0 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain bZIP_2 PF07716.15 OAG43721.1 - 7.2e-08 32.4 7.4 1.5e-07 31.4 7.4 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 OAG43721.1 - 0.0043 17.1 7.2 0.0084 16.2 7.2 1.3 1 0 0 1 1 1 1 bZIP transcription factor PPL5 PF18168.1 OAG43721.1 - 2 7.6 4.2 2.9 7.1 4.2 1.1 1 0 0 1 1 1 0 Prim-pol family 5 zf-H2C2_2 PF13465.6 OAG43722.1 - 5.6e-08 32.9 6.0 6e-06 26.5 0.6 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.26 OAG43722.1 - 1.1e-07 31.9 5.4 1.3e-05 25.4 0.2 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 OAG43722.1 - 4.9e-05 23.2 0.7 0.014 15.4 0.0 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_4 PF13894.6 OAG43722.1 - 0.00015 22.3 5.2 0.008 16.9 0.2 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger FOXP-CC PF16159.5 OAG43722.1 - 0.0028 18.3 10.2 0.12 13.1 0.1 3.6 2 1 2 4 4 4 2 FOXP coiled-coil domain zf-H2C2_5 PF13909.6 OAG43722.1 - 0.055 13.2 1.4 0.79 9.5 0.1 2.6 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-met PF12874.7 OAG43722.1 - 0.072 13.5 0.3 15 6.1 0.0 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 OAG43722.1 - 0.087 12.6 0.6 0.71 9.7 0.0 2.2 2 0 0 2 2 2 0 zinc-finger C2H2-type SOGA PF11365.8 OAG43722.1 - 0.17 13.0 0.7 0.38 11.9 0.1 1.9 2 0 0 2 2 1 0 Protein SOGA Sina PF03145.16 OAG43722.1 - 0.49 10.3 5.6 6.9 6.6 0.7 2.3 1 1 1 2 2 2 0 Seven in absentia protein family zf-C2H2_jaz PF12171.8 OAG43722.1 - 2.1 8.7 5.2 6.5 7.2 0.0 2.8 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding FAD_binding_3 PF01494.19 OAG43723.1 - 1.2e-22 80.7 0.2 3.5e-13 49.5 0.0 2.4 3 0 0 3 3 3 2 FAD binding domain Pyr_redox_2 PF07992.14 OAG43723.1 - 1.1e-11 44.5 0.1 2e-05 24.0 0.0 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAG43723.1 - 2.7e-11 43.6 4.9 9.5e-05 22.1 0.0 2.8 1 1 1 3 3 3 2 FAD dependent oxidoreductase Trp_halogenase PF04820.14 OAG43723.1 - 4.1e-07 29.2 1.5 0.0078 15.1 0.0 2.8 3 0 0 3 3 3 2 Tryptophan halogenase Lycopene_cycl PF05834.12 OAG43723.1 - 6.5e-07 28.7 0.3 0.015 14.4 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein Amino_oxidase PF01593.24 OAG43723.1 - 1.6e-05 24.4 0.2 0.009 15.3 0.0 3.1 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 OAG43723.1 - 9.1e-05 21.8 0.3 0.029 13.6 0.4 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG43723.1 - 9.9e-05 22.5 0.1 0.00035 20.8 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 OAG43723.1 - 0.00057 18.7 0.3 0.088 11.5 0.1 2.3 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox PF00070.27 OAG43723.1 - 0.0027 18.2 1.1 0.61 10.7 0.2 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAG43723.1 - 0.0046 16.1 0.2 0.0097 15.0 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain SE PF08491.10 OAG43723.1 - 0.0048 16.0 0.0 0.42 9.6 0.0 2.3 2 0 0 2 2 2 1 Squalene epoxidase NAD_binding_9 PF13454.6 OAG43723.1 - 0.0086 16.1 0.6 1.7 8.6 0.1 2.6 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.17 OAG43723.1 - 0.029 13.6 0.2 0.058 12.6 0.2 1.5 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.22 OAG43723.1 - 0.14 11.2 0.7 0.29 10.2 0.7 1.7 1 1 0 1 1 1 0 Glucose inhibited division protein A tRNA_SAD PF07973.14 OAG43724.1 - 8.9e-07 28.9 0.4 1.5e-06 28.2 0.4 1.4 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain tRNA-synt_2c PF01411.19 OAG43724.1 - 6.3e-06 25.0 0.0 7.9e-06 24.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) 6PGD PF00393.19 OAG43725.1 - 4.5e-90 301.9 0.0 5.6e-90 301.6 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 OAG43725.1 - 3e-33 115.2 0.0 7.1e-33 114.0 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 OAG43725.1 - 1.8e-05 24.7 0.0 3.2e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 OAG43725.1 - 0.0021 18.3 0.0 0.039 14.2 0.0 2.3 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain UDPG_MGDP_dh_N PF03721.14 OAG43725.1 - 0.0024 17.5 0.0 0.005 16.4 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.16 OAG43725.1 - 0.0033 17.1 0.0 0.006 16.2 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.19 OAG43725.1 - 0.0033 16.8 0.0 0.0062 15.9 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 OAG43725.1 - 0.0065 16.5 0.0 0.014 15.4 0.0 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.17 OAG43725.1 - 0.033 14.8 0.0 0.079 13.6 0.0 1.8 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent AP_endonuc_2 PF01261.24 OAG43726.1 - 4.4e-37 127.6 0.0 6.9e-37 126.9 0.0 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel MFS_1 PF07690.16 OAG43727.1 - 2.8e-36 125.2 59.7 1.4e-35 122.9 57.2 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily AgrB PF04647.15 OAG43727.1 - 0.061 12.6 1.9 0.22 10.8 1.9 2.0 1 0 0 1 1 1 0 Accessory gene regulator B Sec2p PF06428.11 OAG43728.1 - 0.0012 18.8 2.9 0.0017 18.2 2.9 1.3 1 0 0 1 1 1 1 GDP/GTP exchange factor Sec2p SlyX PF04102.12 OAG43728.1 - 0.0025 18.4 1.4 0.0025 18.4 1.4 2.1 2 1 1 3 3 3 1 SlyX BRE1 PF08647.11 OAG43728.1 - 0.0031 17.6 2.9 0.0043 17.1 2.9 1.2 1 0 0 1 1 1 1 BRE1 E3 ubiquitin ligase HALZ PF02183.18 OAG43728.1 - 0.0098 16.1 0.8 0.02 15.1 0.8 1.5 1 0 0 1 1 1 1 Homeobox associated leucine zipper SHE3 PF17078.5 OAG43728.1 - 0.063 13.0 3.3 0.083 12.6 3.3 1.1 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 Spc7 PF08317.11 OAG43728.1 - 0.08 11.8 3.7 0.089 11.7 3.7 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Cluap1 PF10234.9 OAG43728.1 - 0.082 12.3 5.5 0.097 12.0 5.5 1.0 1 0 0 1 1 1 0 Clusterin-associated protein-1 DivIC PF04977.15 OAG43728.1 - 1.6 8.6 5.6 1.9 8.3 2.2 1.8 1 1 1 2 2 2 0 Septum formation initiator HCMV_UL139 PF12507.8 OAG43728.1 - 4.9 7.5 8.1 1.8 8.9 4.4 2.0 2 1 0 2 2 2 0 Human Cytomegalovirus UL139 protein Adenylsucc_synt PF00709.21 OAG43729.1 - 2.1e-165 550.8 0.0 2.4e-165 550.5 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase NB-ARC PF00931.22 OAG43731.1 - 1e-05 24.9 0.0 1.8e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain PRK PF00485.18 OAG43731.1 - 5.2e-05 23.1 0.0 0.00023 20.9 0.0 1.9 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.6 OAG43731.1 - 0.00051 20.2 0.0 0.036 14.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 OAG43731.1 - 0.0012 18.8 0.0 0.0019 18.1 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 OAG43731.1 - 0.0029 17.9 0.0 0.017 15.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 OAG43731.1 - 0.0032 18.0 0.1 0.024 15.2 0.0 2.4 2 1 1 3 3 3 1 AAA domain AAA PF00004.29 OAG43731.1 - 0.0045 17.4 0.0 0.0085 16.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OAG43731.1 - 0.0049 17.3 0.4 0.013 15.9 0.4 2.0 1 1 0 1 1 1 1 AAA ATPase domain Thymidylate_kin PF02223.17 OAG43731.1 - 0.0088 15.7 0.0 0.91 9.2 0.0 2.3 2 0 0 2 2 2 1 Thymidylate kinase DUF2075 PF09848.9 OAG43731.1 - 0.027 13.7 0.0 0.04 13.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Ploopntkinase3 PF18751.1 OAG43731.1 - 0.04 13.8 0.0 0.077 12.9 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 cobW PF02492.19 OAG43731.1 - 0.06 12.9 0.1 0.096 12.3 0.1 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 OAG43731.1 - 0.061 13.0 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 OAG43731.1 - 0.065 13.1 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 NTPase T2SSE PF00437.20 OAG43731.1 - 0.08 12.0 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein ResIII PF04851.15 OAG43731.1 - 0.14 12.2 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit RNA_helicase PF00910.22 OAG43731.1 - 0.15 12.4 0.0 0.29 11.6 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_17 PF13207.6 OAG43731.1 - 0.16 12.4 0.1 0.16 12.4 0.1 2.4 2 1 1 3 3 3 0 AAA domain AAA_19 PF13245.6 OAG43731.1 - 0.18 12.1 0.1 0.24 11.7 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 OAG43731.1 - 0.18 12.2 0.2 0.25 11.8 0.2 1.5 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.6 OAG43731.1 - 0.21 11.3 0.7 0.91 9.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 OAG43731.1 - 0.21 11.6 0.5 6.8 6.7 0.0 2.2 2 0 0 2 2 2 0 Helicase HerA, central domain CbiA PF01656.23 OAG43731.1 - 0.23 11.5 0.6 0.65 10.1 0.7 1.9 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Viral_helicase1 PF01443.18 OAG43731.1 - 0.25 11.1 0.6 0.56 9.9 0.6 1.6 1 1 1 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_28 PF13521.6 OAG43731.1 - 1.4 9.1 5.6 0.98 9.6 0.1 2.5 2 0 0 2 2 2 0 AAA domain MBOAT_2 PF13813.6 OAG43733.1 - 9.5e-09 35.4 2.4 3.5e-08 33.6 2.4 2.0 1 1 0 1 1 1 1 Membrane bound O-acyl transferase family Pkinase PF00069.25 OAG43734.1 - 1.9e-72 243.8 0.0 5.5e-72 242.3 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG43734.1 - 4.9e-50 170.2 0.0 8.4e-50 169.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAG43734.1 - 0.0015 17.4 0.0 0.004 16.0 0.0 1.7 1 0 0 1 1 1 1 Fungal protein kinase GerD PF17898.1 OAG43734.1 - 0.013 15.4 1.0 0.049 13.6 0.5 2.2 2 0 0 2 2 2 0 Spore germination GerD central core domain DUF383 PF04063.14 OAG43734.1 - 0.015 14.9 1.4 0.1 12.3 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF383) Kinase-like PF14531.6 OAG43734.1 - 0.035 13.4 0.0 0.17 11.2 0.0 2.0 2 0 0 2 2 2 0 Kinase-like CLASP_N PF12348.8 OAG43734.1 - 0.063 12.8 4.3 3.1 7.3 1.0 2.5 2 0 0 2 2 2 0 CLASP N terminal VPS9 PF02204.18 OAG43736.1 - 1.8e-29 102.0 0.0 2.9e-29 101.3 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 OAG43736.1 - 5.2e-14 52.3 0.1 1.6e-13 50.8 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF5601) CUE PF02845.16 OAG43736.1 - 1.7e-08 34.0 0.2 1.6e-07 30.9 0.0 2.3 2 0 0 2 2 2 1 CUE domain Asn_synthase PF00733.21 OAG43737.1 - 3.6e-16 59.8 0.9 5.5e-07 29.6 0.0 3.2 2 1 1 3 3 3 3 Asparagine synthase GATase_7 PF13537.6 OAG43737.1 - 7.3e-07 29.1 0.0 2.1e-06 27.7 0.0 1.8 1 1 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 OAG43737.1 - 0.0014 18.1 0.0 0.0027 17.2 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein GATase_6 PF13522.6 OAG43737.1 - 0.0045 17.2 0.0 0.012 15.8 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain MFS_1 PF07690.16 OAG43738.1 - 5.7e-38 130.7 77.8 1.1e-34 120.0 49.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG43738.1 - 3.1e-05 23.0 36.0 0.0063 15.4 4.4 3.0 2 1 1 3 3 3 3 Sugar (and other) transporter OspD PF03207.13 OAG43738.1 - 0.12 11.8 0.1 0.17 11.2 0.1 1.1 1 0 0 1 1 1 0 Borrelia outer surface protein D (OspD) MFS_1 PF07690.16 OAG43739.1 - 1.8e-22 79.7 59.1 1.2e-21 77.0 38.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily RRM_1 PF00076.22 OAG43740.1 - 4e-13 49.0 0.0 6.4e-13 48.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF812 PF05667.11 OAG43740.1 - 1 8.2 5.8 1.3 7.9 5.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Sin_N PF04801.13 OAG43740.1 - 2.1 7.5 4.8 2.8 7.1 4.8 1.0 1 0 0 1 1 1 0 Sin-like protein conserved region HECT PF00632.25 OAG43741.1 - 1.2e-98 330.4 0.1 1.6e-98 330.0 0.1 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 OAG43741.1 - 8.8e-34 115.3 20.2 1.2e-11 44.5 1.4 4.0 4 0 0 4 4 4 3 WW domain C2 PF00168.30 OAG43741.1 - 6.4e-20 71.4 0.0 1.5e-19 70.2 0.0 1.6 1 0 0 1 1 1 1 C2 domain Clr5 PF14420.6 OAG43742.1 - 0.00023 21.3 0.1 0.00053 20.2 0.1 1.6 1 0 0 1 1 1 1 Clr5 domain RF3_C PF16658.5 OAG43742.1 - 0.036 13.9 0.2 0.065 13.1 0.2 1.4 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain YrzO PF14142.6 OAG43742.1 - 0.22 11.4 0.0 0.45 10.4 0.0 1.4 1 0 0 1 1 1 0 YrzO-like protein MFS_1 PF07690.16 OAG43743.1 - 4.7e-31 108.0 31.3 4.7e-31 108.0 31.3 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Alpha-amylase PF00128.24 OAG43744.1 - 1.6e-105 353.4 0.1 4e-105 352.1 0.0 1.6 2 1 0 2 2 2 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 OAG43744.1 - 6.2e-09 35.9 0.0 1.2e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain hDGE_amylase PF14701.6 OAG43744.1 - 0.00034 19.9 0.0 0.00066 18.9 0.0 1.4 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain FAA_hydrolase PF01557.18 OAG43745.1 - 6.7e-52 176.3 0.0 9.1e-52 175.9 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 OAG43745.1 - 5.3e-33 113.4 0.0 8.7e-33 112.7 0.0 1.3 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal p450 PF00067.22 OAG43746.1 - 4.2e-60 203.8 0.0 4.8e-60 203.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HgmA PF04209.13 OAG43747.1 - 1.1e-193 643.8 0.4 1.2e-193 643.6 0.4 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase HLH PF00010.26 OAG43748.1 - 6e-12 45.3 0.0 1.2e-11 44.3 0.0 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PPP4R2 PF09184.11 OAG43748.1 - 0.029 14.0 3.0 0.033 13.8 2.1 1.4 1 1 0 1 1 1 0 PPP4R2 TFIIA PF03153.13 OAG43748.1 - 0.13 12.2 14.9 0.0092 16.0 9.1 1.8 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit NOA36 PF06524.12 OAG43748.1 - 0.14 11.5 3.1 0.21 10.9 3.1 1.2 1 0 0 1 1 1 0 NOA36 protein PBP1_TM PF14812.6 OAG43748.1 - 10 6.6 8.7 1.2 9.5 3.6 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Aminotran_4 PF01063.19 OAG43749.1 - 1.9e-30 106.4 0.0 2.3e-30 106.1 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV Pkinase PF00069.25 OAG43750.1 - 1.7e-17 63.7 0.0 6.5e-17 61.8 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG43750.1 - 6e-09 35.5 0.0 4.6e-08 32.6 0.0 2.3 2 1 0 2 2 2 1 Protein tyrosine kinase MIP PF00230.20 OAG43751.1 - 3.1e-41 141.6 11.3 8e-41 140.2 11.3 1.6 1 1 0 1 1 1 1 Major intrinsic protein SPW PF03779.14 OAG43751.1 - 0.027 14.1 0.9 0.027 14.1 0.9 3.0 3 0 0 3 3 3 0 SPW repeat MFS_1 PF07690.16 OAG43752.1 - 9e-27 93.9 33.7 9e-27 93.9 33.7 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Peptidase_M50 PF02163.22 OAG43752.1 - 0.036 13.3 0.1 0.089 12.0 0.0 1.6 2 0 0 2 2 2 0 Peptidase family M50 AMP-binding PF00501.28 OAG43753.1 - 6.8e-77 258.8 0.0 8.7e-77 258.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG43753.1 - 6.1e-15 56.0 0.8 1.4e-14 54.8 0.1 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain EF-hand_1 PF00036.32 OAG43753.1 - 0.16 11.6 0.1 0.9 9.2 0.0 2.4 2 0 0 2 2 2 0 EF hand Fungal_trans PF04082.18 OAG43754.1 - 3.3e-21 75.5 3.7 5.2e-21 74.9 3.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glycos_transf_3 PF00591.21 OAG43755.1 - 6.4e-61 206.1 0.0 1.7e-48 165.5 0.0 2.1 2 0 0 2 2 2 2 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 OAG43755.1 - 6.4e-08 32.3 0.0 1.9e-07 30.8 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family, helical bundle domain TPR_10 PF13374.6 OAG43756.1 - 0.062 13.2 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Bys1 PF04681.12 OAG43757.1 - 0.00011 22.2 1.9 0.00025 21.0 1.9 1.5 1 1 0 1 1 1 1 Blastomyces yeast-phase-specific protein VIT1 PF01988.19 OAG43758.1 - 1.6e-61 208.0 2.0 2e-61 207.6 2.0 1.1 1 0 0 1 1 1 1 VIT family DUF4328 PF14219.6 OAG43758.1 - 0.052 13.1 2.9 0.13 11.8 2.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) DUF535 PF04393.13 OAG43758.1 - 0.2 10.9 0.2 1.1 8.5 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF535) DUF2207 PF09972.9 OAG43758.1 - 0.22 10.3 0.0 0.38 9.5 0.0 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Mod_r PF07200.13 OAG43760.1 - 2.9e-22 79.3 0.9 3.6e-22 79.0 0.9 1.1 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein ALIX_LYPXL_bnd PF13949.6 OAG43760.1 - 0.0017 17.7 3.5 0.0034 16.7 3.3 1.6 1 1 0 1 1 1 1 ALIX V-shaped domain binding to HIV TolA_bind_tri PF16331.5 OAG43760.1 - 0.0062 16.6 2.2 0.0062 16.6 2.2 1.9 2 0 0 2 2 2 1 TolA binding protein trimerisation DivIC PF04977.15 OAG43760.1 - 0.01 15.6 2.0 0.029 14.1 0.7 2.0 2 0 0 2 2 2 0 Septum formation initiator UPF0242 PF06785.11 OAG43760.1 - 0.014 15.5 1.8 0.023 14.8 1.8 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TPR_MLP1_2 PF07926.12 OAG43760.1 - 0.035 14.2 0.7 0.035 14.2 0.7 1.9 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein HOOK PF05622.12 OAG43760.1 - 0.04 12.1 0.3 0.045 11.9 0.3 1.1 1 0 0 1 1 1 0 HOOK protein Shugoshin_N PF07558.11 OAG43760.1 - 0.084 12.8 0.9 0.15 11.9 0.9 1.4 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region CENP-H PF05837.12 OAG43760.1 - 0.24 11.8 4.0 0.42 11.0 4.0 1.4 1 0 0 1 1 1 0 Centromere protein H (CENP-H) APG6_N PF17675.1 OAG43760.1 - 0.39 11.3 3.9 0.21 12.1 1.3 1.7 2 0 0 2 2 2 0 Apg6 coiled-coil region DUF4164 PF13747.6 OAG43760.1 - 1.9 8.8 5.7 1.1 9.6 0.6 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4164) SF3A2 PF16835.5 OAG43761.1 - 1.6e-38 130.9 0.0 2.5e-38 130.3 0.0 1.3 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 OAG43761.1 - 1.9e-05 24.9 2.5 2e-05 24.8 0.5 2.0 2 0 0 2 2 2 1 Zinc-finger of C2H2 type PRP4 PF08799.11 OAG43761.1 - 0.05 13.2 1.5 0.11 12.1 1.5 1.6 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like Ank_2 PF12796.7 OAG43762.1 - 4.3e-25 88.1 0.1 2.4e-10 40.9 0.1 4.4 3 2 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAG43762.1 - 3.9e-22 78.3 2.7 7.8e-05 23.2 0.0 6.0 5 1 1 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG43762.1 - 1.9e-19 67.7 3.8 2.7e-06 27.3 0.0 6.4 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 OAG43762.1 - 4.5e-18 65.1 8.8 7.4e-07 29.3 0.0 6.1 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 OAG43762.1 - 1.9e-12 47.0 9.6 6.3e-05 23.2 0.0 5.6 6 0 0 6 6 6 2 Ankyrin repeat SRP-alpha_N PF04086.13 OAG43763.1 - 0.33 10.8 10.5 0.4 10.6 10.5 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Ndc1_Nup PF09531.10 OAG43763.1 - 2.7 6.6 5.8 3.2 6.3 5.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup ThrE PF06738.12 OAG43764.1 - 4.6e-58 196.4 15.2 2.6e-54 184.1 2.5 2.2 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 OAG43764.1 - 3.1e-13 50.0 23.8 1.1e-12 48.2 9.4 2.8 3 0 0 3 3 3 2 Threonine/Serine exporter, ThrE DUF2263 PF10021.9 OAG43765.1 - 1.2e-19 71.2 0.0 5.5e-19 69.0 0.0 2.0 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Macro PF01661.21 OAG43765.1 - 0.029 14.4 0.0 0.046 13.8 0.0 1.3 1 0 0 1 1 1 0 Macro domain Enkurin PF13864.6 OAG43767.1 - 0.029 14.8 0.1 0.05 14.0 0.1 1.3 1 0 0 1 1 1 0 Calmodulin-binding DUF1129 PF06570.11 OAG43767.1 - 0.082 12.4 2.0 0.091 12.2 0.3 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) PAP2_3 PF14378.6 OAG43767.1 - 1.5 8.5 8.4 2.5 7.8 8.4 1.5 1 1 0 1 1 1 0 PAP2 superfamily Ribosomal_L3 PF00297.22 OAG43768.1 - 9e-18 64.4 4.1 7.4e-16 58.1 1.3 2.1 1 1 1 2 2 2 2 Ribosomal protein L3 DUF4267 PF14087.6 OAG43770.1 - 9.3e-21 74.0 4.5 1.1e-20 73.7 4.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) DUF5337 PF17272.2 OAG43770.1 - 0.017 14.9 0.4 0.049 13.5 0.0 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5337) Ank_4 PF13637.6 OAG43771.1 - 8.6e-33 112.3 13.9 1.4e-11 44.7 0.0 5.6 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 OAG43771.1 - 2.6e-30 104.9 4.1 8.8e-12 45.5 0.0 3.6 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OAG43771.1 - 2.6e-19 69.0 11.3 2.9e-07 30.6 0.1 5.6 2 2 4 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG43771.1 - 1.2e-18 65.3 8.0 0.00017 21.8 0.0 7.0 7 0 0 7 7 7 5 Ankyrin repeat SPX PF03105.19 OAG43771.1 - 1.1e-13 51.9 10.7 5.1e-09 36.5 0.3 2.5 2 1 1 3 3 3 2 SPX domain Ank PF00023.30 OAG43771.1 - 2.8e-13 49.6 10.1 0.0053 17.2 0.0 7.6 7 0 0 7 7 7 3 Ankyrin repeat GDPD PF03009.17 OAG43771.1 - 8.8e-09 35.5 0.0 2.3e-08 34.1 0.0 1.6 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Mito_carr PF00153.27 OAG43773.1 - 1.9e-67 223.3 6.3 7.3e-25 86.7 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4748 PF15932.5 OAG43773.1 - 0.068 12.9 0.8 0.21 11.4 0.8 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4748) PsbR PF04725.12 OAG43773.1 - 0.076 13.4 0.3 11 6.4 0.1 2.7 2 0 0 2 2 2 0 Photosystem II 10 kDa polypeptide PsbR Kri1 PF05178.12 OAG43774.1 - 1.4e-29 102.7 17.0 1.4e-29 102.7 17.0 4.8 6 1 0 6 6 6 1 KRI1-like family Kri1_C PF12936.7 OAG43774.1 - 1.1e-28 99.2 0.3 1.1e-28 99.2 0.3 4.5 4 2 1 5 5 5 1 KRI1-like family C-terminal CRISPR_Cse2 PF09485.10 OAG43774.1 - 0.1 13.1 5.8 0.3 11.6 5.8 1.8 1 0 0 1 1 1 0 CRISPR-associated protein Cse2 (CRISPR_cse2) Velvet PF11754.8 OAG43774.1 - 0.94 9.4 8.0 0.66 9.9 2.3 2.3 2 0 0 2 2 2 0 Velvet factor VASt PF16016.5 OAG43775.1 - 1.3e-36 126.3 0.0 2.3e-36 125.5 0.0 1.4 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain BAR_3 PF16746.5 OAG43775.1 - 7e-16 58.6 0.4 1.2e-15 57.9 0.0 1.6 2 0 0 2 2 2 1 BAR domain of APPL family PH PF00169.29 OAG43775.1 - 2.5e-09 37.6 0.0 1.1e-08 35.6 0.0 2.2 2 0 0 2 2 2 1 PH domain GRAM PF02893.20 OAG43775.1 - 0.0023 17.8 0.0 0.0053 16.6 0.0 1.6 1 0 0 1 1 1 1 GRAM domain Solute_trans_a PF03619.16 OAG43777.1 - 5.9e-64 216.1 8.7 7.2e-64 215.9 8.7 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DUF3611 PF12263.8 OAG43777.1 - 0.053 13.4 0.3 0.65 9.9 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3611) Acyl-CoA_dh_1 PF00441.24 OAG43778.1 - 2.3e-34 118.8 3.5 3.3e-34 118.2 3.5 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 OAG43778.1 - 1e-22 80.1 0.1 1.7e-22 79.4 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 OAG43778.1 - 6.1e-14 52.6 0.7 3.3e-13 50.3 0.1 2.5 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 OAG43778.1 - 1.7e-08 34.8 1.7 3.1e-08 34.0 1.7 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpcH_HpaI PF03328.14 OAG43779.1 - 1.7e-31 109.1 0.0 2.5e-31 108.6 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family DUF836 PF05768.14 OAG43780.1 - 7.5e-09 35.9 0.1 2.1e-08 34.4 0.1 1.8 1 1 0 1 1 1 1 Glutaredoxin-like domain (DUF836) MFS_1 PF07690.16 OAG43781.1 - 1.2e-32 113.2 35.3 1.2e-32 113.2 35.3 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily UPF0182 PF03699.13 OAG43781.1 - 0.015 13.5 0.3 0.028 12.6 0.3 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) DUF4579 PF15158.6 OAG43781.1 - 2.2 8.0 5.6 0.45 10.2 1.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4579) Fungal_trans PF04082.18 OAG43782.1 - 0.0014 17.8 0.0 0.0028 16.7 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain p450 PF00067.22 OAG43783.1 - 6.3e-64 216.4 0.0 8.3e-64 216.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Leu_zip PF15294.6 OAG43784.1 - 0.012 15.1 0.7 0.012 15.1 0.7 2.1 2 0 0 2 2 2 0 Leucine zipper FlxA PF14282.6 OAG43784.1 - 0.13 12.2 4.0 0.43 10.6 4.0 1.9 1 0 0 1 1 1 0 FlxA-like protein ACOX PF01756.19 OAG43784.1 - 0.18 11.3 0.2 0.48 10.0 0.0 1.7 2 0 0 2 2 2 0 Acyl-CoA oxidase DUF3138 PF11336.8 OAG43784.1 - 0.67 8.5 1.6 1.8 7.1 0.4 2.1 1 1 2 3 3 3 0 Protein of unknown function (DUF3138) CdvA PF18822.1 OAG43784.1 - 1.2 9.0 5.7 3.5 7.5 0.2 3.1 3 0 0 3 3 3 0 CdvA-like coiled-coil domain DivIC PF04977.15 OAG43784.1 - 2.1 8.2 4.5 13 5.6 0.3 2.4 2 0 0 2 2 2 0 Septum formation initiator Anp1 PF03452.14 OAG43786.1 - 1.5e-107 358.9 0.0 1.9e-107 358.6 0.0 1.1 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.26 OAG43786.1 - 0.0044 16.9 0.5 0.028 14.3 0.1 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 2 MFS_1 PF07690.16 OAG43789.1 - 3.2e-10 39.5 36.3 3.2e-10 39.5 36.3 4.0 2 2 1 3 3 3 2 Major Facilitator Superfamily LapA_dom PF06305.11 OAG43789.1 - 2.3 8.1 8.0 0.63 9.9 0.2 3.7 4 0 0 4 4 4 0 Lipopolysaccharide assembly protein A domain Barwin PF00967.17 OAG43790.1 - 0.02 14.7 0.9 0.032 14.1 0.9 1.2 1 0 0 1 1 1 0 Barwin family ABC1 PF03109.16 OAG43791.1 - 1.1e-30 106.3 0.0 1.8e-30 105.5 0.0 1.4 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.22 OAG43791.1 - 0.066 12.8 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Mur_ligase_M PF08245.12 OAG43792.1 - 7.9e-07 29.2 0.0 1.3e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 Mur ligase middle domain Acetyltransf_10 PF13673.7 OAG43793.1 - 9.4e-08 32.0 0.0 1.9e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAG43793.1 - 2.8e-07 30.8 0.0 1e-06 29.0 0.0 2.2 2 1 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OAG43793.1 - 8.8e-06 26.1 0.0 2.3e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 OAG43793.1 - 0.1 12.7 0.0 0.29 11.3 0.0 1.7 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 OAG43793.1 - 0.16 12.1 0.0 0.3 11.2 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Fungal_trans_2 PF11951.8 OAG43794.1 - 2.7e-08 33.1 0.0 5.8e-08 32.0 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Choline_kinase PF01633.20 OAG43795.1 - 5.6e-43 147.0 0.0 6.1e-42 143.6 0.0 2.3 2 0 0 2 2 2 1 Choline/ethanolamine kinase CPL PF08144.11 OAG43795.1 - 8.4e-30 104.0 0.0 1.8e-28 99.7 0.0 2.7 2 0 0 2 2 2 1 CPL (NUC119) domain APH PF01636.23 OAG43795.1 - 4e-05 23.7 0.1 0.00011 22.3 0.1 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF5588 PF17826.1 OAG43795.1 - 0.036 13.0 1.1 0.06 12.2 1.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5588) MFS_1 PF07690.16 OAG43796.1 - 3.3e-21 75.6 15.8 4.3e-21 75.2 15.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily zf-C2H2 PF00096.26 OAG43797.1 - 0.0055 17.1 0.1 0.0055 17.1 0.1 3.1 3 0 0 3 3 3 1 Zinc finger, C2H2 type FOXP-CC PF16159.5 OAG43797.1 - 0.067 13.8 0.7 0.067 13.8 0.7 2.8 2 1 1 3 3 3 0 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 OAG43797.1 - 0.11 13.4 0.1 0.11 13.4 0.1 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger zf_CopZ PF18423.1 OAG43797.1 - 0.31 11.0 2.1 4.6 7.3 1.9 2.7 1 1 1 2 2 2 0 Zinc binding domain zf-C2H2 PF00096.26 OAG43798.1 - 0.0083 16.5 0.1 0.0083 16.5 0.1 2.6 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAG43798.1 - 0.053 14.4 0.1 0.053 14.4 0.1 3.7 3 1 0 3 3 3 0 C2H2-type zinc finger Guanylate_kin PF00625.21 OAG43800.1 - 1.9e-57 193.9 0.0 2.6e-57 193.5 0.0 1.1 1 0 0 1 1 1 1 Guanylate kinase AAA_24 PF13479.6 OAG43800.1 - 6.5e-07 29.3 0.1 0.033 13.9 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 OAG43800.1 - 7.8e-07 29.6 0.2 2.5e-06 28.0 0.2 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 OAG43800.1 - 8.3e-07 29.3 0.1 1.8e-05 25.0 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 OAG43800.1 - 6.8e-06 26.6 0.0 2.3e-05 24.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 OAG43800.1 - 4.8e-05 23.7 0.0 0.00016 21.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 OAG43800.1 - 8.6e-05 22.8 0.0 0.00095 19.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 OAG43800.1 - 0.002 18.6 0.1 0.0033 17.9 0.1 1.7 1 1 0 1 1 1 1 ABC transporter AAA PF00004.29 OAG43800.1 - 0.0023 18.4 0.3 0.039 14.4 0.0 2.2 1 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 OAG43800.1 - 0.0032 17.4 0.0 0.0052 16.7 0.0 1.5 2 0 0 2 2 1 1 Rad17 P-loop domain RsgA_GTPase PF03193.16 OAG43800.1 - 0.004 17.1 0.0 0.0074 16.2 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_14 PF13173.6 OAG43800.1 - 0.0069 16.4 0.0 0.019 15.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 OAG43800.1 - 0.0078 15.9 0.0 0.02 14.6 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain NACHT PF05729.12 OAG43800.1 - 0.0087 16.0 0.0 0.021 14.8 0.0 1.6 2 0 0 2 2 2 1 NACHT domain ATPase_2 PF01637.18 OAG43800.1 - 0.0092 15.9 0.0 0.012 15.6 0.0 1.7 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea MMR_HSR1 PF01926.23 OAG43800.1 - 0.0094 16.0 0.0 0.025 14.7 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 OAG43800.1 - 0.019 15.3 0.1 0.059 13.8 0.0 1.9 2 0 0 2 2 1 0 RNA helicase dNK PF01712.19 OAG43800.1 - 0.026 14.4 0.1 0.47 10.3 0.0 2.2 2 0 0 2 2 2 0 Deoxynucleoside kinase DUF2075 PF09848.9 OAG43800.1 - 0.028 13.7 0.0 0.038 13.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 OAG43800.1 - 0.032 13.9 0.0 0.061 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 OAG43800.1 - 0.041 13.4 0.0 0.082 12.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region cobW PF02492.19 OAG43800.1 - 0.056 13.0 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain T2SSE PF00437.20 OAG43800.1 - 0.075 12.1 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Adeno_IVa2 PF02456.15 OAG43800.1 - 0.086 11.6 0.1 0.14 10.9 0.1 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein NTPase_1 PF03266.15 OAG43800.1 - 0.094 12.6 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 NTPase NB-ARC PF00931.22 OAG43800.1 - 0.11 11.7 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Cytidylate_kin PF02224.18 OAG43800.1 - 0.14 11.9 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 Cytidylate kinase AAA_5 PF07728.14 OAG43800.1 - 0.18 11.8 0.0 0.41 10.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_23 PF13476.6 OAG43800.1 - 0.31 11.5 2.4 0.48 10.9 2.4 1.8 1 1 0 1 1 1 0 AAA domain Septin PF00735.18 OAG43801.1 - 1.2e-112 375.8 0.5 1.4e-112 375.6 0.5 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 OAG43801.1 - 6e-08 32.8 0.0 1.4e-07 31.5 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 OAG43801.1 - 3.6e-06 26.5 0.0 6.8e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 OAG43801.1 - 1.1e-05 25.4 0.5 8.3e-05 22.5 0.1 2.1 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 OAG43801.1 - 1.7e-05 24.4 0.5 0.0041 16.7 0.0 2.3 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 OAG43801.1 - 0.00075 19.6 0.3 0.83 9.7 0.2 2.5 1 1 1 2 2 2 2 Dynamin family NB-ARC PF00931.22 OAG43801.1 - 0.0024 17.1 0.1 0.0044 16.2 0.1 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_7 PF12775.7 OAG43801.1 - 0.0076 15.8 0.0 0.046 13.2 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_16 PF13191.6 OAG43801.1 - 0.0076 16.6 0.0 0.025 15.0 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 OAG43801.1 - 0.0089 16.3 0.0 0.017 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 OAG43801.1 - 0.011 16.3 0.6 0.016 15.7 0.6 1.8 1 1 0 1 1 1 0 ABC transporter Gtr1_RagA PF04670.12 OAG43801.1 - 0.037 13.4 0.0 0.4 10.0 0.0 2.1 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region G-alpha PF00503.20 OAG43801.1 - 0.058 12.5 1.0 0.3 10.2 0.2 2.0 1 1 1 2 2 2 0 G-protein alpha subunit FtsK_SpoIIIE PF01580.18 OAG43801.1 - 0.06 12.7 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family T2SSE PF00437.20 OAG43801.1 - 0.081 12.0 0.0 0.19 10.7 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_23 PF13476.6 OAG43801.1 - 0.11 13.0 0.4 0.19 12.2 0.2 1.6 1 1 0 1 1 1 0 AAA domain Microtub_bd PF16796.5 OAG43801.1 - 0.11 12.4 0.2 0.33 10.9 0.0 1.9 2 1 0 2 2 2 0 Microtubule binding Roc PF08477.13 OAG43801.1 - 0.13 12.4 0.0 0.28 11.4 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 OAG43801.1 - 0.18 11.6 0.0 0.39 10.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain WD40 PF00400.32 OAG43802.1 - 4.8e-26 90.5 11.1 6.3e-09 36.3 0.9 7.2 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG43802.1 - 2.8e-15 56.4 1.3 0.0038 17.5 0.6 5.3 1 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OAG43802.1 - 1.3e-07 31.7 0.0 0.0015 18.4 0.0 3.1 2 1 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 OAG43802.1 - 1.7e-07 30.1 0.0 1.5e-06 27.0 0.0 2.0 1 1 0 1 1 1 1 Cytochrome D1 heme domain Nbas_N PF15492.6 OAG43802.1 - 0.0052 16.2 0.8 0.48 9.7 0.1 3.1 2 1 2 4 4 4 1 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 OAG43802.1 - 0.0078 14.9 0.3 0.12 11.0 0.0 2.5 2 1 1 3 3 3 1 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 OAG43802.1 - 0.018 14.0 0.1 0.48 9.3 0.0 2.8 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 OAG43802.1 - 0.04 13.2 0.0 5.4 6.3 0.0 3.2 4 0 0 4 4 4 0 WD40-like domain IceA2 PF05862.11 OAG43802.1 - 0.042 13.8 0.1 0.16 11.9 0.1 2.0 1 1 1 2 2 2 0 Helicobacter pylori IceA2 protein Hira PF07569.11 OAG43802.1 - 0.11 12.2 0.1 9.9 5.8 0.0 2.4 2 0 0 2 2 2 0 TUP1-like enhancer of split Sulfate_transp PF00916.20 OAG43803.1 - 0.0069 15.2 0.1 0.0071 15.1 0.1 1.1 1 0 0 1 1 1 1 Sulfate permease family Aim19 PF10315.9 OAG43803.1 - 0.018 15.3 0.1 0.023 15.0 0.1 1.3 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 19 DUF1977 PF09320.11 OAG43804.1 - 1.8e-26 92.4 1.1 2.1e-26 92.2 0.1 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1977) DnaJ PF00226.31 OAG43804.1 - 3.7e-22 78.2 1.3 6.9e-22 77.3 0.2 1.9 2 0 0 2 2 2 1 DnaJ domain AT_hook PF02178.19 OAG43804.1 - 0.02 14.7 0.9 0.05 13.5 0.9 1.7 1 0 0 1 1 1 0 AT hook motif Ufd2P_core PF10408.9 OAG43805.1 - 2e-215 717.1 17.7 2.5e-215 716.8 17.7 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 OAG43805.1 - 2e-24 85.5 1.8 2e-24 85.5 1.8 3.0 3 0 0 3 3 3 1 U-box domain FAD_SOX PF18371.1 OAG43805.1 - 0.005 17.2 1.2 4.6 7.7 0.1 3.0 2 0 0 2 2 2 2 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase DUF2203 PF09969.9 OAG43805.1 - 0.076 13.7 0.9 2.1 9.1 0.1 2.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Not3 PF04065.15 OAG43805.1 - 0.13 11.7 4.6 4 6.8 0.6 2.6 2 0 0 2 2 2 0 Not1 N-terminal domain, CCR4-Not complex component SIMPL PF04402.14 OAG43805.1 - 0.32 11.4 1.5 0.37 11.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF541) Methyltransf_23 PF13489.6 OAG43806.1 - 3.2e-09 36.8 0.0 4.8e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG43806.1 - 9.2e-08 32.0 0.0 3.6e-07 30.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG43806.1 - 2.3e-07 31.5 0.0 1.2e-06 29.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG43806.1 - 3.8e-07 30.7 0.0 1.6e-06 28.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG43806.1 - 2.1e-06 28.4 0.0 2e-05 25.2 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAG43806.1 - 0.23 10.8 0.0 0.53 9.6 0.0 1.7 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family adh_short PF00106.25 OAG43807.1 - 1.5e-36 125.7 0.0 2.6e-36 124.9 0.0 1.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG43807.1 - 1.8e-35 122.6 0.0 3.1e-35 121.8 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG43807.1 - 7.8e-15 55.2 0.5 1e-13 51.6 0.5 2.0 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG43807.1 - 0.0025 17.3 0.0 0.054 12.9 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAG43807.1 - 0.047 13.1 0.0 3.2 7.1 0.0 2.1 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase AtuA PF07287.11 OAG43808.1 - 1.7e-122 408.5 0.5 2.1e-122 408.2 0.5 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA AMP-binding PF00501.28 OAG43809.1 - 2.6e-85 286.6 0.0 4e-85 286.0 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Abhydrolase_3 PF07859.13 OAG43809.1 - 7.1e-47 160.0 0.1 1.8e-46 158.7 0.1 1.7 1 0 0 1 1 1 1 alpha/beta hydrolase fold AMP-binding_C PF13193.6 OAG43809.1 - 1.1e-13 51.9 0.3 3.2e-13 50.5 0.3 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain COesterase PF00135.28 OAG43809.1 - 3e-07 29.7 0.0 7.3e-07 28.4 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family Fungal_trans PF04082.18 OAG43809.1 - 0.026 13.6 1.6 0.042 12.9 1.6 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain Say1_Mug180 PF10340.9 OAG43809.1 - 0.075 11.9 0.0 0.15 10.9 0.0 1.4 1 0 0 1 1 1 0 Steryl acetyl hydrolase Fungal_trans PF04082.18 OAG43810.1 - 1.8e-26 92.8 0.0 3.2e-26 92.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cys_rich_VLP PF14194.6 OAG43810.1 - 0.017 15.2 0.1 0.045 13.9 0.1 1.6 1 0 0 1 1 1 0 Cysteine-rich VLP Acyl-CoA_dh_1 PF00441.24 OAG43811.1 - 2.5e-32 112.2 2.4 4.1e-32 111.5 2.4 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 OAG43811.1 - 1.5e-19 69.9 0.0 2.8e-19 69.1 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 OAG43811.1 - 1e-14 54.9 3.2 1.3e-14 54.6 2.0 1.8 1 1 1 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 OAG43811.1 - 1.3e-12 48.4 0.0 3.3e-12 47.1 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain DUF2950 PF11453.8 OAG43811.1 - 0.12 11.5 0.1 0.18 11.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2950) DUF2922 PF11148.8 OAG43811.1 - 0.21 11.3 0.3 0.41 10.4 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2922) p450 PF00067.22 OAG43814.1 - 2.3e-72 244.2 0.0 3.1e-72 243.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4286 PF14114.6 OAG43815.1 - 0.0032 17.9 0.0 2.3 8.8 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4286) Sugar_tr PF00083.24 OAG43816.1 - 7.6e-88 295.3 22.6 8.8e-88 295.1 22.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG43816.1 - 1e-32 113.5 62.1 4e-30 104.9 32.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily FMO-like PF00743.19 OAG43817.1 - 6.6e-13 47.9 0.0 3.3e-11 42.3 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 OAG43817.1 - 5.9e-07 28.9 0.0 5.1e-05 22.6 0.0 2.2 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 OAG43817.1 - 6.1e-05 22.4 0.0 0.0027 17.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase adh_short_C2 PF13561.6 OAG43818.1 - 2.1e-65 220.6 1.9 2.4e-65 220.4 1.9 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG43818.1 - 7.6e-51 172.3 2.1 9.1e-51 172.1 2.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG43818.1 - 1.5e-14 54.3 2.2 2.2e-14 53.7 2.2 1.1 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 OAG43818.1 - 0.013 15.4 0.0 0.021 14.7 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 OAG43818.1 - 0.013 15.0 0.0 0.12 11.9 0.0 2.0 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family ThiF PF00899.21 OAG43818.1 - 0.77 9.1 3.4 4.3 6.6 0.0 2.8 1 1 0 2 2 2 0 ThiF family TRI12 PF06609.13 OAG43819.1 - 1.7e-42 145.6 18.6 2.1e-42 145.4 18.6 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG43819.1 - 6.6e-19 68.0 43.6 6.6e-19 68.0 43.6 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG43819.1 - 6.6e-09 35.1 11.0 6.6e-09 35.1 11.0 3.0 1 1 2 3 3 3 1 Sugar (and other) transporter ABM PF03992.16 OAG43820.1 - 6.4e-12 45.4 1.2 5.5e-11 42.4 0.2 2.2 2 0 0 2 2 2 1 Antibiotic biosynthesis monooxygenase NIPSNAP PF07978.13 OAG43821.1 - 1.6e-27 95.7 0.1 1.7e-27 95.6 0.1 1.0 1 0 0 1 1 1 1 NIPSNAP Topo_Zn_Ribbon PF08272.11 OAG43821.1 - 0.26 11.0 1.1 0.92 9.2 0.2 2.1 2 0 0 2 2 2 0 Topoisomerase I zinc-ribbon-like Peptidase_M19 PF01244.21 OAG43822.1 - 7.6e-98 327.6 0.0 9e-98 327.3 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) DIOX_N PF14226.6 OAG43823.1 - 4.5e-22 79.0 0.0 7e-22 78.4 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OAG43823.1 - 3.1e-19 69.3 0.1 9.2e-19 67.8 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Na_Ca_ex PF01699.24 OAG43824.1 - 7.3e-29 100.7 19.5 1.5e-15 57.4 9.0 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF4577 PF15145.6 OAG43824.1 - 0.16 12.0 0.1 0.65 10.0 0.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4577) Abhydrolase_9_N PF15420.6 OAG43825.1 - 0.019 14.9 0.5 0.043 13.8 0.1 1.7 1 1 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus AA_permease_2 PF13520.6 OAG43825.1 - 0.16 10.8 5.3 0.069 12.0 0.8 2.0 1 1 1 2 2 2 0 Amino acid permease RRM_1 PF00076.22 OAG43826.1 - 1.6e-14 53.5 0.5 5e-14 51.9 0.1 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 OAG43826.1 - 0.025 14.6 0.1 0.066 13.2 0.1 1.7 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RL PF17797.1 OAG43826.1 - 0.055 13.4 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 RL domain TMP-TENI PF02581.17 OAG43826.1 - 0.075 12.4 0.1 0.56 9.5 0.0 2.2 2 0 0 2 2 2 0 Thiamine monophosphate synthase RTC PF01137.21 OAG43827.1 - 2.9e-37 128.0 0.1 1.4e-27 96.4 0.0 2.2 2 0 0 2 2 2 2 RNA 3'-terminal phosphate cyclase Ricin_B_lectin PF00652.22 OAG43829.1 - 2e-17 63.6 0.0 0.00046 20.4 0.0 4.2 2 2 2 4 4 4 4 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 OAG43829.1 - 8.9e-08 32.8 0.0 1.4 9.7 0.0 4.5 4 0 0 4 4 4 2 Ricin-type beta-trefoil lectin domain-like FIST_C PF10442.9 OAG43829.1 - 0.0096 15.9 0.0 6.7 6.7 0.0 2.4 2 0 0 2 2 2 2 FIST C domain CDtoxinA PF03498.14 OAG43829.1 - 0.018 14.6 0.2 3 7.4 0.0 3.4 3 1 2 5 5 5 0 Cytolethal distending toxin A/C domain FAM199X PF15814.5 OAG43829.1 - 1.2 8.1 9.3 2 7.4 9.3 1.3 1 0 0 1 1 1 0 Protein family FAM199X FAD_binding_3 PF01494.19 OAG43830.1 - 9e-20 71.2 0.1 1.3e-13 50.9 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 OAG43830.1 - 4.3e-09 36.0 0.2 6.7e-06 25.5 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAG43830.1 - 1.2e-07 32.1 0.1 1e-06 29.2 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAG43830.1 - 1.8e-07 31.1 0.6 3.6e-05 23.5 0.4 2.4 1 1 1 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAG43830.1 - 0.00044 20.4 0.1 0.001 19.2 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 OAG43830.1 - 0.0063 15.8 0.1 0.0063 15.8 0.1 1.5 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 OAG43830.1 - 0.011 14.8 0.0 0.17 10.9 0.1 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein Trp_halogenase PF04820.14 OAG43830.1 - 0.017 14.0 1.6 0.63 8.8 0.3 2.1 1 1 0 2 2 2 0 Tryptophan halogenase Pyr_redox_3 PF13738.6 OAG43830.1 - 0.032 13.5 0.0 0.054 12.7 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 OAG43830.1 - 0.064 12.5 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase ApbA PF02558.16 OAG43830.1 - 0.074 12.7 1.0 0.17 11.5 0.1 2.0 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA GIDA PF01134.22 OAG43830.1 - 0.092 11.8 0.2 0.13 11.4 0.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A CoA_transf_3 PF02515.17 OAG43830.1 - 0.22 10.6 0.1 0.22 10.6 0.1 1.6 2 0 0 2 2 2 0 CoA-transferase family III FAD_binding_2 PF00890.24 OAG43830.1 - 0.29 10.2 3.4 0.11 11.5 0.5 1.8 3 0 0 3 3 3 0 FAD binding domain P_proprotein PF01483.20 OAG43831.1 - 0.1 12.6 0.4 2.8 8.0 0.0 2.3 1 1 1 2 2 2 0 Proprotein convertase P-domain HTH_Tnp_1_2 PF13022.6 OAG43832.1 - 0.0077 16.4 0.2 0.011 15.9 0.2 1.2 1 0 0 1 1 1 1 Helix-turn-helix of insertion element transposase SHS2_FTSA PF02491.20 OAG43832.1 - 0.048 14.1 0.3 0.44 11.0 0.3 2.1 1 1 0 1 1 1 0 SHS2 domain inserted in FTSA HTH_Tnp_IS630 PF01710.16 OAG43832.1 - 0.066 13.3 0.2 0.086 12.9 0.2 1.2 1 0 0 1 1 1 0 Transposase APH PF01636.23 OAG43833.1 - 1.1e-09 38.6 0.0 4e-09 36.8 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 OAG43833.1 - 0.0011 18.6 0.0 0.0018 17.9 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.11 OAG43833.1 - 0.0067 15.3 0.0 0.0098 14.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) EcKinase PF02958.20 OAG43833.1 - 0.061 12.6 0.0 0.16 11.3 0.0 1.7 2 0 0 2 2 2 0 Ecdysteroid kinase DUF3348 PF11828.8 OAG43833.1 - 0.11 12.1 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3348) Pkinase PF00069.25 OAG43834.1 - 2.3e-12 46.8 0.0 6.3e-07 29.0 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAG43834.1 - 6.1e-08 32.3 0.0 1.4e-05 24.5 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Emaravirus_P4 PF16505.5 OAG43834.1 - 0.073 12.1 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 P4 movement protein of Emaravirus, and the 30K superfamily Fungal_trans_2 PF11951.8 OAG43835.1 - 8.4e-06 24.8 0.3 0.025 13.4 0.1 2.3 2 1 0 2 2 2 2 Fungal specific transcription factor domain adh_short PF00106.25 OAG43836.1 - 3e-24 85.6 0.0 3.3e-24 85.4 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG43836.1 - 1.6e-14 54.1 0.0 1.7e-14 53.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG43836.1 - 4.7e-08 33.2 0.0 5.7e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG43836.1 - 2.5e-06 27.1 0.1 3.2e-06 26.8 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 OAG43836.1 - 0.00033 20.7 0.6 0.00082 19.4 0.6 1.8 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.6 OAG43836.1 - 0.0015 18.4 0.1 0.0017 18.3 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_2 PF03446.15 OAG43836.1 - 0.0016 18.7 0.0 0.0026 17.9 0.0 1.5 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase GDP_Man_Dehyd PF16363.5 OAG43836.1 - 0.0069 15.8 0.1 0.0075 15.7 0.1 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase ADH_zinc_N PF00107.26 OAG43836.1 - 0.024 14.6 0.0 0.029 14.3 0.0 1.2 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Sacchrp_dh_NADP PF03435.18 OAG43836.1 - 0.076 13.3 0.1 0.093 13.0 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain RmlD_sub_bind PF04321.17 OAG43836.1 - 0.094 11.8 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain ApbA PF02558.16 OAG43836.1 - 0.11 12.2 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Nop14 PF04147.12 OAG43837.1 - 0.0008 17.8 43.5 0.0018 16.6 43.5 1.5 1 0 0 1 1 1 1 Nop14-like family TFIIF_alpha PF05793.12 OAG43837.1 - 6.2 5.3 45.7 8.7 4.8 45.7 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DDHD PF02862.17 OAG43837.1 - 7.1 6.7 6.8 19 5.3 6.8 1.8 1 1 0 1 1 1 0 DDHD domain SNF2_N PF00176.23 OAG43839.1 - 5.7e-18 64.8 0.0 1.3e-17 63.5 0.0 1.5 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OAG43839.1 - 2e-10 41.0 0.0 9.4e-10 38.8 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG43839.1 - 0.039 14.0 0.0 0.14 12.2 0.0 1.9 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit zf-C2H2 PF00096.26 OAG43842.1 - 3.8e-06 27.1 19.5 0.72 10.4 0.2 6.6 6 0 0 6 6 6 3 Zinc finger, C2H2 type zf-C2H2_aberr PF17017.5 OAG43842.1 - 9.2e-05 22.7 2.7 3.3 7.8 0.0 4.9 3 2 2 5 5 5 1 Aberrant zinc-finger zf-C2H2_4 PF13894.6 OAG43842.1 - 0.00027 21.5 25.4 0.61 11.1 0.5 7.1 7 0 0 7 7 7 2 C2H2-type zinc finger Transpos_assoc PF13963.6 OAG43842.1 - 0.006 16.9 0.9 0.082 13.2 0.0 3.2 3 1 1 4 4 4 1 Transposase-associated domain DUF3435 PF11917.8 OAG43842.1 - 0.031 13.2 0.0 0.071 12.0 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3435) DUF2336 PF10098.9 OAG43842.1 - 0.071 12.6 2.4 5.6 6.4 0.1 3.0 3 0 0 3 3 3 0 Uncharacterised protein conserved in bacteria (DUF2336) FOXP-CC PF16159.5 OAG43842.1 - 0.11 13.2 11.7 0.73 10.5 0.6 4.6 5 0 0 5 5 5 0 FOXP coiled-coil domain PHA_gran_rgn PF09650.10 OAG43842.1 - 1.4 9.2 5.4 29 5.0 0.1 3.2 3 0 0 3 3 3 0 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) zf-Di19 PF05605.12 OAG43842.1 - 1.5 9.2 10.3 27 5.2 0.2 4.3 4 0 0 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding CpeS PF09367.10 OAG43843.1 - 0.061 13.2 0.4 15 5.4 0.0 2.7 2 0 0 2 2 2 0 CpeS-like protein Peptidase_M49 PF03571.15 OAG43845.1 - 1.4e-242 806.0 0.0 1.8e-242 805.7 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M49 Abhydrolase_6 PF12697.7 OAG43847.1 - 5.9e-12 46.7 1.9 8.9e-12 46.1 1.9 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG43847.1 - 8.4e-08 31.8 0.0 1.4e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OAG43847.1 - 0.00047 19.9 0.0 0.00094 18.9 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 OAG43847.1 - 0.14 11.1 0.0 0.28 10.1 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase enzyme Ndr PF03096.14 OAG43847.1 - 0.17 10.5 0.0 0.26 10.0 0.0 1.2 1 0 0 1 1 1 0 Ndr family PTCB-BRCT PF12738.7 OAG43848.1 - 1.6e-35 120.8 3.3 3.6e-21 74.9 0.6 5.3 6 0 0 6 6 6 4 twin BRCT domain RTT107_BRCT_5 PF16770.5 OAG43848.1 - 4.7e-31 106.6 1.2 3.6e-27 94.2 0.1 4.3 4 0 0 4 4 4 2 Regulator of Ty1 transposition protein 107 BRCT domain BRCT PF00533.26 OAG43848.1 - 1.7e-30 105.2 0.0 1.5e-10 41.3 0.0 6.1 6 0 0 6 6 6 4 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 OAG43848.1 - 2e-28 98.6 0.0 0.00035 20.9 0.0 6.4 6 0 0 6 6 6 6 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 OAG43848.1 - 2.4e-12 47.0 0.0 0.00017 21.8 0.0 4.6 4 0 0 4 4 4 3 DNA ligase 3 BRCT domain ESCRT-II PF05871.12 OAG43849.1 - 5e-52 175.9 1.2 6.3e-52 175.5 0.6 1.4 2 0 0 2 2 2 1 ESCRT-II complex subunit CLAMP PF14769.6 OAG43849.1 - 0.023 15.2 0.2 0.41 11.1 0.1 2.4 2 0 0 2 2 2 0 Flagellar C1a complex subunit C1a-32 PHD PF00628.29 OAG43850.1 - 7.2e-09 35.4 9.3 1.5e-08 34.4 9.3 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 OAG43850.1 - 0.012 15.2 5.5 0.012 15.2 5.5 1.7 2 0 0 2 2 2 0 PHD-finger C1_2 PF03107.16 OAG43850.1 - 0.63 10.4 8.6 0.097 13.0 3.7 2.0 2 0 0 2 2 2 0 C1 domain 2-Hacid_dh_C PF02826.19 OAG43851.1 - 5.8e-36 123.5 0.0 8.5e-36 123.0 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 OAG43851.1 - 1.1e-14 54.3 0.0 1.4e-14 53.9 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NmrA PF05368.13 OAG43852.1 - 1.3e-27 96.8 0.0 1.8e-27 96.4 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG43852.1 - 5.5e-11 42.7 0.0 1.1e-10 41.7 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAG43852.1 - 2e-05 24.2 0.1 0.00092 18.7 0.1 2.3 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 OAG43852.1 - 0.0008 19.8 0.1 0.01 16.3 0.0 2.2 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 OAG43852.1 - 0.024 14.9 0.0 0.052 13.8 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain KR PF08659.10 OAG43852.1 - 0.027 14.4 0.1 0.051 13.5 0.1 1.4 1 0 0 1 1 1 0 KR domain 3Beta_HSD PF01073.19 OAG43852.1 - 0.079 12.0 0.1 0.12 11.4 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family S1-P1_nuclease PF02265.16 OAG43853.1 - 1.2e-69 235.0 0.6 1.3e-69 234.8 0.6 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease Aconitase PF00330.20 OAG43854.1 - 2.5e-148 494.9 0.0 3.1e-148 494.6 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 OAG43854.1 - 2.1e-38 131.6 0.0 3.4e-38 130.9 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain TPR_10 PF13374.6 OAG43855.1 - 2.1e-73 240.4 50.9 2.4e-09 36.7 0.1 11.5 12 0 0 12 12 11 9 Tetratricopeptide repeat TPR_12 PF13424.6 OAG43855.1 - 2.9e-56 187.7 41.2 4.4e-13 49.3 1.0 7.7 5 2 2 8 8 8 6 Tetratricopeptide repeat TPR_14 PF13428.6 OAG43855.1 - 1.4e-27 94.0 26.5 0.02 15.7 0.1 9.8 8 1 1 9 9 8 8 Tetratricopeptide repeat TPR_19 PF14559.6 OAG43855.1 - 5.2e-22 78.1 29.0 0.0023 18.4 1.1 9.0 2 1 7 9 9 8 7 Tetratricopeptide repeat Patatin PF01734.22 OAG43855.1 - 1.2e-21 77.9 0.0 3.5e-21 76.3 0.0 1.9 1 0 0 1 1 1 1 Patatin-like phospholipase TPR_2 PF07719.17 OAG43855.1 - 1.8e-20 71.3 28.8 0.19 11.9 0.1 10.8 11 0 0 11 11 11 8 Tetratricopeptide repeat TPR_8 PF13181.6 OAG43855.1 - 3.4e-20 70.5 14.1 1.3 9.4 0.0 10.9 11 0 0 11 11 11 5 Tetratricopeptide repeat ANAPC3 PF12895.7 OAG43855.1 - 2.2e-19 69.4 7.1 0.0038 17.4 0.1 7.8 1 1 6 7 7 7 6 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.6 OAG43855.1 - 4.8e-19 68.5 32.0 0.038 14.3 0.3 9.5 2 1 7 9 9 9 8 Tetratricopeptide repeat PPR PF01535.20 OAG43855.1 - 2e-16 59.0 2.9 7.5 7.0 0.0 9.8 10 0 0 10 10 9 0 PPR repeat TPR_6 PF13174.6 OAG43855.1 - 8.7e-16 57.4 14.0 1.8 9.3 0.0 10.6 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_7 PF13176.6 OAG43855.1 - 1.6e-14 52.8 24.0 0.32 11.1 0.0 10.1 10 0 0 10 10 9 6 Tetratricopeptide repeat NB-ARC PF00931.22 OAG43855.1 - 2.2e-14 53.2 0.0 5.7e-14 51.9 0.1 1.7 2 0 0 2 2 2 1 NB-ARC domain TPR_4 PF07721.14 OAG43855.1 - 3.7e-13 48.7 42.2 0.21 12.3 0.4 11.0 12 0 0 12 12 9 6 Tetratricopeptide repeat Fis1_TPR_N PF14852.6 OAG43855.1 - 4.8e-10 38.9 9.0 17 5.2 0.0 8.6 8 0 0 8 8 8 0 Fis1 N-terminal tetratricopeptide repeat TPR_1 PF00515.28 OAG43855.1 - 9.7e-09 34.7 18.1 15 5.6 0.0 10.2 11 0 0 11 11 10 0 Tetratricopeptide repeat TPR_MalT PF17874.1 OAG43855.1 - 2.3e-08 33.8 37.5 0.00012 21.5 8.4 3.9 2 1 3 5 5 5 4 MalT-like TPR region TPR_16 PF13432.6 OAG43855.1 - 4.1e-07 30.5 34.2 0.0098 16.5 0.3 8.5 3 1 7 10 10 8 5 Tetratricopeptide repeat AAA_22 PF13401.6 OAG43855.1 - 8.6e-06 26.1 0.2 9.6e-05 22.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OAG43855.1 - 0.00014 22.3 0.2 0.00014 22.3 0.2 3.0 2 2 0 2 2 1 1 AAA ATPase domain TPR_17 PF13431.6 OAG43855.1 - 0.0012 19.0 9.2 65 4.2 0.0 7.7 8 0 0 8 8 8 0 Tetratricopeptide repeat NACHT PF05729.12 OAG43855.1 - 0.0016 18.4 0.0 0.0036 17.3 0.0 1.7 1 0 0 1 1 1 1 NACHT domain TPR_11 PF13414.6 OAG43855.1 - 0.0068 16.1 19.2 41 4.0 0.0 9.1 9 0 0 9 9 9 0 TPR repeat PPR_1 PF12854.7 OAG43855.1 - 0.0094 15.6 21.2 55 3.6 0.1 8.8 9 0 0 9 9 9 0 PPR repeat PHP PF02811.19 OAG43856.1 - 2e-13 51.0 0.0 6.8e-13 49.3 0.0 1.9 2 1 0 2 2 2 1 PHP domain Cys_Met_Meta_PP PF01053.20 OAG43857.1 - 3.8e-138 460.2 0.0 4.4e-138 460.0 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 OAG43857.1 - 1.6e-06 27.6 0.0 2.3e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Met_gamma_lyase PF06838.11 OAG43857.1 - 1.5e-05 23.8 0.0 7.4e-05 21.4 0.0 1.8 1 1 0 1 1 1 1 Methionine gamma-lyase Aminotran_5 PF00266.19 OAG43857.1 - 2e-05 23.7 0.0 4e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 OAG43857.1 - 0.0002 20.8 0.0 0.00039 19.9 0.0 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family GDC-P PF02347.16 OAG43857.1 - 0.0052 15.7 0.0 0.0074 15.2 0.0 1.1 1 0 0 1 1 1 1 Glycine cleavage system P-protein B12-binding PF02310.19 OAG43857.1 - 0.05 13.6 0.0 0.41 10.7 0.0 2.2 2 0 0 2 2 2 0 B12 binding domain LysM PF01476.20 OAG43859.1 - 0.012 15.7 0.0 0.022 14.8 0.0 1.4 1 0 0 1 1 1 0 LysM domain AFG1_ATPase PF03969.16 OAG43860.1 - 7.1e-99 331.1 0.0 5.1e-94 315.1 0.0 2.2 2 0 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.6 OAG43860.1 - 0.00014 22.3 0.9 0.61 10.5 0.0 3.3 3 1 0 4 4 4 2 AAA ATPase domain AAA_22 PF13401.6 OAG43860.1 - 0.00074 19.8 0.2 0.05 13.9 0.0 3.0 2 1 0 2 2 2 1 AAA domain Bac_DnaA PF00308.18 OAG43860.1 - 0.00079 19.3 0.2 0.68 9.7 0.1 2.4 2 0 0 2 2 2 2 Bacterial dnaA protein AAA_14 PF13173.6 OAG43860.1 - 0.0014 18.7 0.0 0.0035 17.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 OAG43860.1 - 0.0077 16.7 0.8 0.09 13.2 0.0 2.7 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 OAG43860.1 - 0.063 13.3 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE UvrD-helicase PF00580.21 OAG43860.1 - 0.083 12.4 0.0 0.26 10.7 0.0 1.8 2 1 0 2 2 2 0 UvrD/REP helicase N-terminal domain AAA_5 PF07728.14 OAG43860.1 - 0.097 12.7 0.0 0.22 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Sacchrp_dh_NADP PF03435.18 OAG43860.1 - 0.1 12.8 0.0 0.43 10.8 0.0 2.0 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain DsbG_N PF18257.1 OAG43860.1 - 0.12 12.6 0.1 0.28 11.4 0.1 1.6 1 0 0 1 1 1 0 Disulfide isomerase DsbG N-terminal RNA_helicase PF00910.22 OAG43860.1 - 0.16 12.4 0.0 0.48 10.8 0.0 1.9 1 1 0 1 1 1 0 RNA helicase SH3_1 PF00018.28 OAG43861.1 - 1.1e-25 88.9 0.4 6e-12 45.0 0.0 3.4 4 0 0 4 4 4 2 SH3 domain SH3_9 PF14604.6 OAG43861.1 - 1.1e-12 47.6 3.8 4.5e-07 29.6 0.1 2.9 3 0 0 3 3 3 2 Variant SH3 domain PX PF00787.24 OAG43861.1 - 4.5e-12 46.0 0.0 1.1e-11 44.7 0.0 1.7 1 0 0 1 1 1 1 PX domain SH3_2 PF07653.17 OAG43861.1 - 1.2e-09 37.7 0.0 2.1e-06 27.3 0.0 2.9 2 0 0 2 2 2 2 Variant SH3 domain PB1 PF00564.24 OAG43861.1 - 2.7e-08 33.6 0.3 5e-08 32.8 0.3 1.4 1 0 0 1 1 1 1 PB1 domain GH97_C PF14509.6 OAG43861.1 - 0.087 13.1 0.0 0.24 11.6 0.0 1.7 1 0 0 1 1 1 0 Glycosyl-hydrolase 97 C-terminal, oligomerisation SAC3_GANP PF03399.16 OAG43862.1 - 6.6e-26 91.4 1.5 6.9e-24 84.7 1.5 2.1 1 1 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 OAG43862.1 - 0.00019 21.4 0.0 0.00053 20.0 0.0 1.7 2 0 0 2 2 2 1 CSN8/PSMD8/EIF3K family EAP30 PF04157.16 OAG43863.1 - 2.4e-40 138.3 0.7 2.8e-40 138.1 0.7 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family PigN PF04987.14 OAG43864.1 - 5.7e-164 546.3 34.0 5.7e-164 546.3 34.0 1.6 2 0 0 2 2 2 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.22 OAG43864.1 - 1.1e-08 35.1 4.6 8.2e-07 28.9 4.6 2.3 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 OAG43864.1 - 1.8e-07 30.9 0.1 2.6e-07 30.3 0.1 1.4 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.18 OAG43864.1 - 2.6e-05 23.7 0.0 4.2e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Lipoxygenase PF00305.19 OAG43866.1 - 5.6e-28 97.8 0.1 9.3e-28 97.1 0.1 1.3 1 0 0 1 1 1 1 Lipoxygenase NACHT PF05729.12 OAG43868.1 - 3e-08 33.8 0.1 1.1e-07 31.9 0.1 2.0 1 0 0 1 1 1 1 NACHT domain SesA PF17107.5 OAG43868.1 - 3.3e-06 27.3 0.5 1.3e-05 25.4 0.5 2.1 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases AAA_22 PF13401.6 OAG43868.1 - 0.0069 16.7 0.5 0.048 13.9 0.0 2.7 3 1 0 3 3 3 1 AAA domain ABC_tran PF00005.27 OAG43868.1 - 0.037 14.5 0.0 0.14 12.7 0.0 1.9 1 0 0 1 1 1 0 ABC transporter AAA_23 PF13476.6 OAG43868.1 - 0.04 14.4 0.0 0.04 14.4 0.0 3.0 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.17 OAG43868.1 - 0.096 12.8 1.6 24 4.9 0.0 3.3 3 0 0 3 3 3 0 Helicase HerA, central domain AAA_29 PF13555.6 OAG43868.1 - 0.12 12.2 0.1 0.26 11.1 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain cobW PF02492.19 OAG43868.1 - 0.17 11.5 0.0 0.4 10.2 0.0 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Methyltransf_3 PF01596.17 OAG43869.1 - 1.9e-36 125.3 0.0 2.4e-36 124.9 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 OAG43869.1 - 5.3e-15 56.3 0.0 1.9e-14 54.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG43869.1 - 2e-05 24.4 0.0 4.3e-05 23.4 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 OAG43869.1 - 7.2e-05 22.6 0.0 0.0001 22.2 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.7 OAG43869.1 - 8.5e-05 22.5 0.0 0.00014 21.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG43869.1 - 0.0049 17.5 0.0 0.019 15.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Met_10 PF02475.16 OAG43869.1 - 0.01 15.6 0.0 0.021 14.6 0.0 1.6 1 1 1 2 2 2 0 Met-10+ like-protein Methyltransf_11 PF08241.12 OAG43869.1 - 0.021 15.4 0.0 0.085 13.5 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain CmcI PF04989.12 OAG43869.1 - 0.099 12.3 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Cephalosporin hydroxylase TrmK PF04816.12 OAG43869.1 - 0.099 12.2 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 tRNA (adenine(22)-N(1))-methyltransferase Cons_hypoth95 PF03602.15 OAG43869.1 - 0.15 11.7 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 ACPS PF01648.20 OAG43870.1 - 2.6e-13 50.1 0.0 3.5e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily 4PPT_N PF17837.1 OAG43870.1 - 0.02 15.0 2.4 3.8 7.7 0.1 2.9 2 1 1 3 3 3 0 4'-phosphopantetheinyl transferase N-terminal domain AAT PF03417.16 OAG43871.1 - 3.6e-27 95.5 0.0 4.3e-27 95.3 0.0 1.1 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase MTP18 PF10558.9 OAG43872.1 - 5e-81 270.7 0.1 6.2e-81 270.4 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) adh_short PF00106.25 OAG43874.1 - 6.6e-33 113.8 0.0 8.8e-33 113.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG43874.1 - 1.4e-20 73.8 0.0 2e-20 73.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 OAG43874.1 - 1.3e-05 24.7 0.0 4.6e-05 22.9 0.0 1.7 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) ADH_zinc_N PF00107.26 OAG43874.1 - 0.014 15.4 0.0 0.022 14.8 0.0 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase NAD_binding_10 PF13460.6 OAG43874.1 - 0.019 14.9 0.0 0.03 14.2 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding NmrA PF05368.13 OAG43874.1 - 0.11 12.0 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family CK2S PF15011.6 OAG43875.1 - 0.075 12.9 0.1 0.24 11.3 0.1 1.8 1 0 0 1 1 1 0 Casein Kinase 2 substrate Vps53_N PF04100.12 OAG43875.1 - 0.45 9.4 3.4 0.23 10.4 0.2 2.1 2 0 0 2 2 2 0 Vps53-like, N-terminal Csm1 PF12539.8 OAG43876.1 - 4.1e-28 97.8 1.4 6e-27 94.1 1.4 2.3 1 1 0 1 1 1 1 Chromosome segregation protein Csm1/Pcs1 NYD-SP28 PF14772.6 OAG43876.1 - 0.0031 17.5 3.1 0.0031 17.5 3.1 3.6 2 2 1 4 4 4 1 Sperm tail Lebercilin PF15619.6 OAG43876.1 - 0.0091 15.7 5.6 0.0091 15.7 5.6 3.4 2 2 1 3 3 3 1 Ciliary protein causing Leber congenital amaurosis disease ADIP PF11559.8 OAG43876.1 - 0.017 15.2 7.4 0.017 15.2 7.4 2.6 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Bap31_Bap29_C PF18035.1 OAG43876.1 - 0.1 12.6 4.0 13 5.8 0.6 3.3 3 0 0 3 3 3 0 Bap31/Bap29 cytoplasmic coiled-coil domain DUF948 PF06103.11 OAG43876.1 - 0.18 12.1 1.8 0.59 10.4 0.4 2.7 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) USP8_interact PF08941.10 OAG43876.1 - 0.21 11.4 4.1 0.067 13.0 0.7 2.0 2 0 0 2 2 2 0 USP8 interacting Prominin PF05478.11 OAG43876.1 - 0.71 7.8 3.2 1.1 7.1 3.2 1.2 1 0 0 1 1 1 0 Prominin AAA PF00004.29 OAG43877.1 - 4.2e-36 124.3 0.0 9.4e-36 123.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OAG43877.1 - 4.3e-08 32.8 0.0 8.7e-08 31.9 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 OAG43877.1 - 1.2e-05 25.8 1.9 0.00069 20.0 0.0 2.9 2 1 0 3 3 2 1 AAA ATPase domain RuvB_N PF05496.12 OAG43877.1 - 2.3e-05 24.2 0.0 4.4e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 OAG43877.1 - 5e-05 23.3 0.0 0.00017 21.6 0.0 1.9 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 OAG43877.1 - 0.0001 22.3 0.1 0.00059 19.9 0.1 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 OAG43877.1 - 0.00023 21.5 0.1 0.0081 16.4 0.0 2.6 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.6 OAG43877.1 - 0.00029 21.4 0.0 0.00081 19.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 OAG43877.1 - 0.0005 20.2 0.1 0.0012 19.0 0.0 1.8 2 0 0 2 2 1 1 AAA domain IstB_IS21 PF01695.17 OAG43877.1 - 0.0005 19.8 0.0 0.00093 19.0 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 OAG43877.1 - 0.00085 18.8 0.1 0.0017 17.8 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 OAG43877.1 - 0.0019 18.6 0.0 0.0047 17.3 0.0 1.8 1 0 0 1 1 1 1 RNA helicase AAA_25 PF13481.6 OAG43877.1 - 0.0023 17.5 0.2 0.023 14.3 0.1 2.2 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.14 OAG43877.1 - 0.0028 17.8 0.0 0.0068 16.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) TniB PF05621.11 OAG43877.1 - 0.0035 16.8 0.0 3.4 7.0 0.0 2.6 1 1 1 2 2 2 2 Bacterial TniB protein NACHT PF05729.12 OAG43877.1 - 0.0041 17.0 0.1 0.015 15.2 0.0 2.0 2 0 0 2 2 2 1 NACHT domain DUF815 PF05673.13 OAG43877.1 - 0.0043 16.2 0.0 0.0075 15.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Sigma54_activ_2 PF14532.6 OAG43877.1 - 0.0085 16.2 0.0 0.021 14.9 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_28 PF13521.6 OAG43877.1 - 0.0092 16.2 0.0 0.021 15.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 OAG43877.1 - 0.011 15.7 0.2 0.072 13.0 0.1 2.1 1 1 1 2 2 2 0 Rad17 P-loop domain AAA_24 PF13479.6 OAG43877.1 - 0.011 15.4 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 OAG43877.1 - 0.019 14.9 0.1 0.33 10.8 0.0 2.2 1 1 0 2 2 2 0 ATPase domain predominantly from Archaea Parvo_NS1 PF01057.17 OAG43877.1 - 0.027 13.6 0.2 0.049 12.7 0.0 1.4 2 0 0 2 2 1 0 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.26 OAG43877.1 - 0.033 13.9 0.0 0.065 12.9 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Guanylate_kin PF00625.21 OAG43877.1 - 0.042 13.5 0.0 0.41 10.3 0.0 2.5 3 0 0 3 3 3 0 Guanylate kinase ABC_tran PF00005.27 OAG43877.1 - 0.049 14.1 0.0 0.15 12.6 0.0 1.8 1 0 0 1 1 1 0 ABC transporter AAA_7 PF12775.7 OAG43877.1 - 0.058 12.9 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_11 PF13086.6 OAG43877.1 - 0.065 13.0 0.0 0.13 12.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 OAG43877.1 - 0.08 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase TsaE PF02367.17 OAG43877.1 - 0.091 12.8 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Bac_DnaA PF00308.18 OAG43877.1 - 0.11 12.4 0.0 0.17 11.7 0.0 1.4 1 1 0 1 1 1 0 Bacterial dnaA protein TIP49 PF06068.13 OAG43877.1 - 0.11 11.6 0.1 0.26 10.4 0.0 1.6 2 0 0 2 2 2 0 TIP49 P-loop domain Tna_leader PF08053.11 OAG43877.1 - 0.18 11.8 0.9 0.38 10.8 0.5 1.8 2 0 0 2 2 1 0 Tryptophanase operon leader peptide Fungal_trans PF04082.18 OAG43878.1 - 8.1e-31 107.0 0.0 1.5e-30 106.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG43878.1 - 0.26 11.5 0.5 0.46 10.7 0.5 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain PI3K_1B_p101 PF10486.9 OAG43879.1 - 0.0027 15.6 3.0 0.0025 15.7 3.0 1.2 1 0 0 1 1 1 1 Phosphoinositide 3-kinase gamma adapter protein p101 subunit RPS31 PF17067.5 OAG43879.1 - 0.15 12.2 6.4 1.6 9.0 3.9 2.3 2 0 0 2 2 2 0 Ribosomal protein S31e Fungal_trans PF04082.18 OAG43880.1 - 2.9e-16 59.3 0.7 4.8e-16 58.6 0.7 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG43880.1 - 2e-07 31.0 7.6 3.5e-07 30.2 7.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Transp_cyt_pur PF02133.15 OAG43881.1 - 7.3e-21 74.4 31.7 1e-20 74.0 31.7 1.2 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin FAD_binding_3 PF01494.19 OAG43882.1 - 2.6e-20 73.0 0.1 4.1e-20 72.3 0.1 1.3 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 OAG43882.1 - 5.5e-07 29.1 3.1 0.0026 17.0 0.9 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAG43882.1 - 2.4e-06 27.4 9.8 0.0046 16.6 0.2 2.3 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAG43882.1 - 1.7e-05 24.9 1.5 5.3e-05 23.4 1.5 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 OAG43882.1 - 3.1e-05 23.2 1.6 3.6e-05 23.0 0.4 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 OAG43882.1 - 0.00025 20.3 4.0 0.00025 20.3 4.0 2.0 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 OAG43882.1 - 0.00054 19.4 1.0 0.00075 19.0 1.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 OAG43882.1 - 0.0013 17.6 4.0 0.0035 16.1 1.7 2.0 2 0 0 2 2 2 1 HI0933-like protein Trp_halogenase PF04820.14 OAG43882.1 - 0.0025 16.7 6.8 0.017 14.0 1.2 2.1 1 1 1 2 2 2 2 Tryptophan halogenase Pyr_redox PF00070.27 OAG43882.1 - 0.018 15.6 1.1 0.18 12.4 0.5 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 OAG43882.1 - 0.041 13.2 1.5 0.2 10.9 0.0 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase SE PF08491.10 OAG43882.1 - 0.076 12.0 0.0 0.17 10.9 0.0 1.5 2 0 0 2 2 2 0 Squalene epoxidase Pyr_redox_3 PF13738.6 OAG43882.1 - 0.15 11.3 2.1 0.25 10.5 2.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MCRA PF06100.11 OAG43882.1 - 0.23 10.2 0.4 2.4 6.8 0.3 2.0 2 0 0 2 2 2 0 MCRA family GIDA PF01134.22 OAG43882.1 - 0.62 9.1 2.6 0.88 8.6 2.6 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Fungal_trans PF04082.18 OAG43883.1 - 5.5e-14 51.8 2.6 1.9e-13 50.1 2.5 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG43883.1 - 0.05 13.7 5.5 0.12 12.5 5.5 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Amidohydro_2 PF04909.14 OAG43884.1 - 1e-34 120.7 0.3 1.3e-34 120.3 0.3 1.1 1 0 0 1 1 1 1 Amidohydrolase FMO-like PF00743.19 OAG43885.1 - 3.9e-19 68.5 0.0 3.4e-17 62.1 0.0 2.2 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 OAG43885.1 - 8.7e-15 54.7 0.0 1.5e-12 47.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG43885.1 - 8e-12 45.0 0.0 7.3e-10 38.6 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG43885.1 - 7.1e-10 39.0 0.0 2.8e-08 33.9 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 OAG43885.1 - 1.3e-09 37.6 0.0 3.8e-07 29.6 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 OAG43885.1 - 5.4e-09 36.2 0.1 0.0074 16.3 0.1 4.2 3 1 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.24 OAG43885.1 - 7.7e-05 22.4 0.0 0.19 11.3 0.0 4.0 4 0 0 4 4 4 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 OAG43885.1 - 0.00015 22.3 0.0 0.95 10.1 0.0 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAG43885.1 - 0.00019 20.8 0.1 0.12 11.5 0.0 2.8 3 0 0 3 3 3 2 Thi4 family FAD_binding_3 PF01494.19 OAG43885.1 - 0.0011 18.2 0.2 2.4 7.3 0.0 3.1 3 0 0 3 3 3 2 FAD binding domain NAD_binding_7 PF13241.6 OAG43885.1 - 0.0013 19.2 0.0 1.3 9.5 0.0 2.9 3 0 0 3 3 3 1 Putative NAD(P)-binding Lycopene_cycl PF05834.12 OAG43885.1 - 0.0014 17.7 0.0 0.27 10.2 0.0 2.7 3 0 0 3 3 3 1 Lycopene cyclase protein HI0933_like PF03486.14 OAG43885.1 - 0.0092 14.7 1.1 2.8 6.6 0.0 3.5 4 0 0 4 4 4 1 HI0933-like protein Amino_oxidase PF01593.24 OAG43885.1 - 0.02 14.2 0.1 0.13 11.6 0.0 2.3 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase GIDA PF01134.22 OAG43885.1 - 0.062 12.4 0.0 3.8 6.5 0.0 2.8 3 0 0 3 3 3 0 Glucose inhibited division protein A Shikimate_DH PF01488.20 OAG43885.1 - 0.17 12.0 0.0 0.4 10.7 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase adh_short_C2 PF13561.6 OAG43886.1 - 8.3e-42 143.3 0.3 2.3e-30 105.9 0.9 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG43886.1 - 1.7e-36 125.5 0.9 2.7e-36 124.9 0.9 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG43886.1 - 3e-12 46.8 2.5 1.4e-11 44.6 2.5 2.0 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG43886.1 - 0.00011 21.8 1.1 0.0006 19.3 1.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Abhydrolase_3 PF07859.13 OAG43887.1 - 2.6e-58 197.4 0.0 4e-58 196.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 OAG43887.1 - 2.5e-11 43.2 0.2 1.1e-10 41.1 0.2 1.8 1 1 0 1 1 1 1 Carboxylesterase family DLH PF01738.18 OAG43887.1 - 0.012 15.1 0.0 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 OAG43887.1 - 0.032 14.1 0.0 0.055 13.3 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase AP_endonuc_2 PF01261.24 OAG43887.1 - 0.062 12.7 0.0 0.083 12.3 0.0 1.4 1 1 0 1 1 1 0 Xylose isomerase-like TIM barrel Peptidase_S9 PF00326.21 OAG43887.1 - 0.11 11.9 0.1 3.5 7.1 0.0 2.5 3 0 0 3 3 3 0 Prolyl oligopeptidase family FMO-like PF00743.19 OAG43888.1 - 1.4e-16 60.0 0.1 2.6e-16 59.2 0.1 1.4 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OAG43888.1 - 3.7e-10 39.9 0.0 1.1e-09 38.3 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 OAG43888.1 - 1.7e-07 30.8 0.0 1.9e-06 27.3 0.0 2.4 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAG43888.1 - 3.5e-05 23.6 0.0 0.00049 19.8 0.0 2.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG43888.1 - 4.3e-05 22.9 0.0 0.053 12.7 0.0 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG43888.1 - 0.0002 20.6 0.0 0.052 12.7 0.0 2.7 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 OAG43888.1 - 0.0078 15.5 0.0 0.037 13.3 0.0 1.9 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.22 OAG43888.1 - 0.087 11.9 0.3 0.6 9.1 0.0 2.3 3 0 0 3 3 3 0 Glucose inhibited division protein A NAD_binding_9 PF13454.6 OAG43888.1 - 0.13 12.2 0.5 0.4 10.7 0.0 2.1 3 0 0 3 3 3 0 FAD-NAD(P)-binding HI0933_like PF03486.14 OAG43888.1 - 0.24 10.1 0.1 0.58 8.8 0.1 1.6 1 0 0 1 1 1 0 HI0933-like protein adh_short_C2 PF13561.6 OAG43889.1 - 6.9e-53 179.6 0.1 1.2e-52 178.8 0.1 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG43889.1 - 1.7e-40 138.6 0.0 3.3e-40 137.6 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase DUF3425 PF11905.8 OAG43889.1 - 3.2e-19 69.1 1.4 1.1e-18 67.3 0.2 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3425) KR PF08659.10 OAG43889.1 - 4.2e-08 33.3 0.9 2e-07 31.1 0.0 2.1 2 0 0 2 2 2 1 KR domain bZIP_1 PF00170.21 OAG43889.1 - 0.00035 20.6 12.0 0.0024 17.9 12.1 2.4 1 1 0 1 1 1 1 bZIP transcription factor FlaC_arch PF05377.11 OAG43889.1 - 0.0046 17.3 0.4 0.011 16.1 0.4 1.6 1 0 0 1 1 1 1 Flagella accessory protein C (FlaC) Sacchrp_dh_NADP PF03435.18 OAG43889.1 - 0.27 11.5 0.8 0.45 10.8 0.1 1.7 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain TMCO5 PF14992.6 OAG43889.1 - 0.39 10.3 4.1 0.73 9.4 4.1 1.4 1 0 0 1 1 1 0 TMCO5 family Peptidase_U57 PF05582.12 OAG43889.1 - 0.5 9.6 2.1 0.84 8.8 2.1 1.2 1 0 0 1 1 1 0 YabG peptidase U57 Herpes_UL25 PF01499.16 OAG43889.1 - 0.91 8.0 6.5 1.4 7.4 6.5 1.3 1 0 0 1 1 1 0 Herpesvirus UL25 family BMFP PF04380.13 OAG43889.1 - 3.3 8.3 11.8 7.2 7.2 0.8 3.4 3 0 0 3 3 3 0 Membrane fusogenic activity CCDC53 PF10152.9 OAG43889.1 - 4.7 7.6 14.6 0.14 12.5 7.1 2.1 1 1 1 2 2 2 0 Subunit CCDC53 of WASH complex Striatin PF08232.12 OAG43889.1 - 9.7 6.8 14.0 12 6.4 11.7 2.2 1 1 1 2 2 2 0 Striatin family Sugar_tr PF00083.24 OAG43890.1 - 1.7e-85 287.6 17.3 2e-85 287.4 17.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG43890.1 - 7.9e-20 71.1 53.6 2e-17 63.2 29.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Fe-ADH PF00465.19 OAG43891.1 - 6.3e-101 337.8 0.0 7.8e-101 337.5 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 OAG43891.1 - 2.2e-14 53.8 0.0 1.1e-11 45.0 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Sortase PF04203.13 OAG43891.1 - 0.14 11.9 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 Sortase domain ECH_1 PF00378.20 OAG43892.1 - 3.6e-45 154.2 0.0 5.1e-45 153.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAG43892.1 - 1.6e-22 80.5 0.0 1.9e-21 76.9 0.0 1.9 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 OAG43892.1 - 0.0012 18.8 0.8 0.011 15.7 0.1 2.1 1 1 1 2 2 2 1 Peptidase family S49 Fungal_trans PF04082.18 OAG43893.1 - 6.1e-11 41.9 0.0 1.1e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Polyketide_cyc2 PF10604.9 OAG43894.1 - 2.3e-05 24.7 0.0 3e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport FMN_dh PF01070.18 OAG43895.1 - 2.2e-115 385.4 0.0 2.7e-115 385.1 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 OAG43895.1 - 3.8e-20 71.8 0.0 7.9e-20 70.8 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain IMPDH PF00478.25 OAG43895.1 - 0.0019 17.3 0.2 0.0062 15.6 0.1 1.8 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 OAG43895.1 - 0.0054 15.9 0.0 0.0088 15.2 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.15 OAG43895.1 - 0.0065 15.9 0.0 0.0095 15.4 0.0 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase GvpO PF05800.11 OAG43895.1 - 0.093 12.7 0.1 0.22 11.5 0.1 1.6 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpO AP_endonuc_2 PF01261.24 OAG43895.1 - 0.14 11.5 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel HpcH_HpaI PF03328.14 OAG43896.1 - 1.2e-30 106.3 0.0 1.6e-30 105.9 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family TauD PF02668.16 OAG43897.1 - 2.8e-51 174.9 0.0 3.3e-51 174.6 0.0 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Cyclase PF04199.13 OAG43898.1 - 2.6e-15 56.9 0.0 3.9e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 Putative cyclase FMO-like PF00743.19 OAG43899.1 - 6.6e-15 54.5 0.0 2.7e-12 45.9 0.1 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 OAG43899.1 - 4.7e-08 32.6 0.0 9.3e-06 25.1 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG43899.1 - 6e-06 26.4 0.0 1.4e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 OAG43899.1 - 2.6e-05 23.5 0.0 0.0013 18.0 0.0 3.0 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 OAG43899.1 - 7.2e-05 22.2 0.0 0.00056 19.3 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Crystall_3 PF08964.10 OAG43899.1 - 0.035 14.3 1.1 0.76 10.0 0.1 2.4 2 0 0 2 2 2 0 Beta/Gamma crystallin Thi4 PF01946.17 OAG43899.1 - 0.25 10.6 0.4 14 4.8 0.0 3.0 4 0 0 4 4 4 0 Thi4 family Cyclase PF04199.13 OAG43900.1 - 4.3e-13 49.7 0.0 6e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase DUF1708 PF08101.11 OAG43900.1 - 0.12 11.5 0.0 0.17 11.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1708) AMP-binding PF00501.28 OAG43901.1 - 1.8e-101 339.8 0.0 2.1e-101 339.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG43901.1 - 6.4e-12 46.3 0.0 2e-11 44.7 0.0 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Fungal_trans PF04082.18 OAG43902.1 - 2.7e-23 82.4 0.0 4.8e-23 81.5 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Snapin_Pallidin PF14712.6 OAG43902.1 - 0.15 12.5 0.3 0.27 11.7 0.3 1.4 1 0 0 1 1 1 0 Snapin/Pallidin FMO-like PF00743.19 OAG43903.1 - 1.2e-15 57.0 0.4 5.6e-13 48.2 0.4 2.5 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OAG43903.1 - 1.8e-11 44.1 0.0 9.1e-11 41.8 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAG43903.1 - 5.1e-08 32.5 0.0 0.00093 18.5 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG43903.1 - 2.1e-07 30.4 0.1 3.4e-05 23.2 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 OAG43903.1 - 5.7e-05 22.9 0.6 0.44 10.1 0.0 3.1 2 1 0 3 3 3 2 FAD dependent oxidoreductase Shikimate_DH PF01488.20 OAG43903.1 - 0.0088 16.1 0.0 0.71 9.9 0.0 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.6 OAG43903.1 - 0.014 15.4 0.0 1.1 9.3 0.0 2.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 OAG43903.1 - 0.05 14.2 0.2 5.6 7.6 0.2 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAG43903.1 - 0.058 12.6 0.2 0.26 10.5 0.0 1.9 2 0 0 2 2 2 0 Thi4 family LBR_tudor PF09465.10 OAG43903.1 - 0.1 12.4 0.7 0.48 10.3 0.2 2.3 2 0 0 2 2 2 0 Lamin-B receptor of TUDOR domain DUF5325 PF17259.2 OAG43903.1 - 0.13 12.2 0.1 0.28 11.1 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5325) adh_short_C2 PF13561.6 OAG43904.1 - 2.5e-69 233.4 1.8 2.8e-69 233.2 1.8 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG43904.1 - 1.4e-50 171.5 1.7 1.7e-50 171.2 1.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG43904.1 - 1.5e-12 47.8 1.0 2.2e-12 47.3 1.0 1.2 1 0 0 1 1 1 1 KR domain Ubie_methyltran PF01209.18 OAG43904.1 - 0.037 13.3 0.2 0.06 12.7 0.2 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Ldh_1_N PF00056.23 OAG43904.1 - 0.066 13.3 0.7 0.11 12.5 0.7 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain AhpC-TSA PF00578.21 OAG43904.1 - 0.097 12.6 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 AhpC/TSA family Carboxyl_trans PF01039.22 OAG43905.1 - 7.6e-118 394.3 0.0 9.4e-118 393.9 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain Cyclase PF04199.13 OAG43906.1 - 4e-14 53.0 0.1 7.7e-14 52.1 0.1 1.4 1 1 0 1 1 1 1 Putative cyclase Stirrup PF09061.6 OAG43906.1 - 0.089 13.0 0.2 1.2 9.4 0.0 2.2 1 1 1 2 2 2 0 Stirrup TauD PF02668.16 OAG43907.1 - 9.6e-54 183.0 0.1 1.1e-53 182.7 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family TRI12 PF06609.13 OAG43908.1 - 3.4e-71 240.4 31.3 5.7e-71 239.7 31.3 1.2 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG43908.1 - 1.6e-22 80.0 47.3 1.6e-22 80.0 47.3 2.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG43908.1 - 2.7e-11 43.0 2.4 2.7e-11 43.0 2.4 2.7 4 0 0 4 4 4 2 Sugar (and other) transporter Abhydrolase_3 PF07859.13 OAG43909.1 - 2.8e-35 122.1 0.0 3.7e-35 121.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 OAG43909.1 - 1.3e-19 70.3 0.0 5.1e-19 68.4 0.0 1.7 2 0 0 2 2 2 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 OAG43909.1 - 0.0054 16.2 0.0 0.01 15.3 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family BAAT_C PF08840.11 OAG43909.1 - 0.019 14.9 0.0 0.038 13.9 0.0 1.4 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Hydrolase_4 PF12146.8 OAG43909.1 - 0.12 11.7 0.0 0.29 10.4 0.0 1.6 2 0 0 2 2 2 0 Serine aminopeptidase, S33 COesterase PF00135.28 OAG43909.1 - 0.16 10.8 0.0 9.9 4.9 0.0 2.0 2 0 0 2 2 2 0 Carboxylesterase family FMO-like PF00743.19 OAG43910.1 - 1.9e-16 59.6 0.0 6.4e-16 57.9 0.0 1.7 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OAG43910.1 - 5.6e-15 55.4 0.0 1.1e-14 54.4 0.0 1.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAG43910.1 - 2e-11 43.7 0.0 3.2e-10 39.7 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG43910.1 - 8.7e-07 29.1 0.5 1.7e-05 24.9 0.0 2.8 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 OAG43910.1 - 6.8e-06 26.6 1.2 0.15 12.6 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG43910.1 - 9.6e-05 21.7 0.0 0.0002 20.7 0.0 1.5 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.12 OAG43910.1 - 0.00041 19.5 0.0 0.16 11.0 0.0 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein 2-Hacid_dh_C PF02826.19 OAG43910.1 - 0.00056 19.3 0.0 0.0011 18.3 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 OAG43910.1 - 0.0061 15.8 0.1 0.015 14.6 0.0 1.7 1 1 1 2 2 2 1 FAD binding domain FAD_binding_2 PF00890.24 OAG43910.1 - 0.019 14.1 0.1 0.04 13.0 0.1 1.5 1 0 0 1 1 1 0 FAD binding domain Shikimate_DH PF01488.20 OAG43910.1 - 0.029 14.4 0.0 0.16 12.1 0.0 2.1 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 OAG43910.1 - 0.063 13.7 0.1 0.28 11.6 0.0 2.2 3 0 0 3 3 2 0 Putative NAD(P)-binding 3HCDH_N PF02737.18 OAG43910.1 - 0.28 11.0 1.1 1.1 9.1 0.1 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FMO-like PF00743.19 OAG43911.1 - 1.5e-15 56.6 0.6 1.5e-14 53.4 0.6 2.3 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 OAG43911.1 - 1.2e-08 34.5 2.0 1.2e-06 27.9 0.0 3.3 3 1 2 5 5 5 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 OAG43911.1 - 2e-08 33.9 0.1 2.5e-07 30.3 0.0 2.5 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG43911.1 - 1.7e-06 28.1 0.0 4.5e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 OAG43911.1 - 0.0001 22.3 0.0 0.0062 16.5 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 OAG43911.1 - 0.002 17.4 0.1 0.084 12.1 0.0 2.8 2 2 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 OAG43911.1 - 0.0058 16.7 0.0 3 7.9 0.0 2.6 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 OAG43911.1 - 0.019 15.4 0.1 3.4 8.2 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding Thi4 PF01946.17 OAG43911.1 - 0.11 11.7 0.0 0.24 10.6 0.0 1.5 1 0 0 1 1 1 0 Thi4 family TRI12 PF06609.13 OAG43912.1 - 8.6e-77 258.9 24.9 1.1e-76 258.6 24.9 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG43912.1 - 5.8e-26 91.2 55.4 2.6e-24 85.8 51.3 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG43912.1 - 5.5e-15 55.2 11.3 5.5e-15 55.2 11.3 3.3 3 1 1 4 4 4 2 Sugar (and other) transporter Fungal_trans PF04082.18 OAG43913.1 - 3.4e-10 39.4 0.4 6.5e-10 38.5 0.4 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain ABC_tran_CTD PF16326.5 OAG43913.1 - 0.24 11.7 0.8 8.1 6.8 0.1 2.5 2 0 0 2 2 2 0 ABC transporter C-terminal domain FMN_dh PF01070.18 OAG43914.1 - 9.5e-108 360.3 0.0 7e-103 344.3 0.0 2.1 2 0 0 2 2 2 2 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 OAG43914.1 - 3.3e-21 75.2 0.0 6.6e-21 74.2 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 OAG43914.1 - 4.8e-05 22.7 0.0 7.3e-05 22.1 0.0 1.1 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 OAG43914.1 - 0.0021 17.1 0.0 0.0037 16.3 0.0 1.3 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain adh_short_C2 PF13561.6 OAG43915.1 - 1.8e-56 191.3 0.0 2.4e-56 190.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG43915.1 - 1.4e-46 158.4 0.0 1.7e-46 158.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG43915.1 - 2.1e-07 31.1 0.0 2.1e-06 27.8 0.0 2.1 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG43915.1 - 0.0016 18.0 0.0 0.0027 17.2 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Ank_4 PF13637.6 OAG43916.1 - 7.7e-12 45.5 0.0 0.00026 21.5 0.0 4.4 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 OAG43916.1 - 9.1e-12 45.4 0.0 2.4e-05 24.8 0.0 2.9 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OAG43916.1 - 1.8e-10 40.1 0.0 0.26 12.0 0.0 5.3 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 OAG43916.1 - 9.1e-09 35.4 0.0 0.2 12.2 0.0 4.3 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 OAG43916.1 - 2.6e-08 34.0 0.1 0.52 10.7 0.0 5.5 4 2 2 6 6 6 2 Ankyrin repeats (many copies) Abhydrolase_3 PF07859.13 OAG43917.1 - 8.5e-53 179.3 0.1 1.1e-52 178.9 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 OAG43917.1 - 1.6e-13 50.3 0.0 2e-13 50.0 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 OAG43917.1 - 0.0012 18.3 0.1 0.0085 15.6 0.0 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family UPF0227 PF05728.12 OAG43917.1 - 0.013 15.4 0.1 0.026 14.5 0.0 1.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) Abhydrolase_2 PF02230.16 OAG43917.1 - 0.15 11.8 0.1 0.55 10.0 0.0 2.0 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Pyr_redox_3 PF13738.6 OAG43918.1 - 7.9e-13 48.3 0.0 6.1e-10 38.8 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 OAG43918.1 - 1.6e-10 40.0 0.0 2.5e-08 32.8 0.0 2.3 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 OAG43918.1 - 1.8e-08 34.0 0.0 3.3e-05 23.3 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG43918.1 - 0.00093 18.4 0.0 0.5 9.5 0.0 2.8 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 OAG43918.1 - 0.0065 16.1 3.3 0.1 12.2 1.6 2.9 3 0 0 3 3 3 1 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.19 OAG43918.1 - 0.03 13.7 0.0 0.056 12.8 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_8 PF13450.6 OAG43918.1 - 0.042 14.1 0.1 0.042 14.1 0.1 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.20 OAG43918.1 - 0.05 13.7 0.1 2.1 8.4 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.24 OAG43918.1 - 0.084 11.9 0.3 0.14 11.2 0.3 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 OAG43918.1 - 0.11 13.1 0.8 5.3 7.7 1.3 2.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 OAG43918.1 - 0.49 9.6 1.6 1.1 8.4 1.6 1.6 1 0 0 1 1 1 0 FAD binding domain adh_short_C2 PF13561.6 OAG43919.1 - 4.4e-40 137.7 6.4 2.8e-31 108.9 3.9 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG43919.1 - 5.4e-35 120.6 3.4 7.7e-35 120.1 3.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG43919.1 - 1.4e-06 28.3 0.5 3.4e-06 27.1 0.5 1.6 1 1 0 1 1 1 1 KR domain Spheroidin PF05541.12 OAG43919.1 - 0.015 13.2 0.0 0.02 12.8 0.0 1.2 1 0 0 1 1 1 0 Entomopoxvirus spheroidin protein Sugar_tr PF00083.24 OAG43920.1 - 7.6e-81 272.3 18.3 8.9e-81 272.0 18.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG43920.1 - 2.3e-23 82.7 27.8 2.3e-23 82.7 27.8 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Fungal_trans PF04082.18 OAG43921.1 - 1.6e-32 112.6 1.4 2.8e-32 111.8 1.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain NAD_binding_8 PF13450.6 OAG43922.1 - 5.5e-13 48.9 0.0 1.6e-12 47.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.19 OAG43922.1 - 1.5e-11 43.4 0.1 3.8e-07 28.9 0.2 3.1 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like DAO PF01266.24 OAG43922.1 - 9.7e-05 22.1 0.0 0.031 13.8 0.0 2.6 2 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 OAG43922.1 - 0.00019 21.5 0.0 0.0024 17.9 0.0 2.5 3 0 0 3 3 3 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 OAG43922.1 - 0.011 14.9 0.0 1.8 7.6 0.0 3.3 3 1 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 OAG43922.1 - 0.013 14.7 0.2 0.56 9.4 0.0 2.6 3 0 0 3 3 3 0 Thi4 family Pyr_redox_3 PF13738.6 OAG43922.1 - 0.037 13.3 0.0 0.21 10.8 0.0 2.2 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase adh_short PF00106.25 OAG43923.1 - 5.4e-38 130.4 0.0 7.2e-38 130.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG43923.1 - 9.9e-28 97.3 0.0 1.3e-27 96.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG43923.1 - 0.00093 19.2 0.7 0.38 10.6 0.1 2.4 2 1 0 2 2 2 2 KR domain Epimerase PF01370.21 OAG43923.1 - 0.1 12.0 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family TRI12 PF06609.13 OAG43924.1 - 4.7e-74 249.9 27.8 6e-74 249.5 27.8 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG43924.1 - 4.2e-20 72.0 40.0 4.2e-20 72.0 40.0 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Pox_A14 PF05767.12 OAG43924.1 - 0.095 12.9 2.0 0.19 11.9 0.3 2.5 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 Yip1 PF04893.17 OAG43926.1 - 2.5e-15 56.6 5.3 4.7e-15 55.7 5.3 1.4 1 0 0 1 1 1 1 Yip1 domain Ran_BP1 PF00638.18 OAG43926.1 - 4.4e-15 56.0 0.1 1.2e-09 38.5 0.3 2.4 2 0 0 2 2 2 2 RanBP1 domain ADP_ribosyl_GH PF03747.14 OAG43927.1 - 1.3e-69 235.2 0.0 1.5e-69 235.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase DUF3419 PF11899.8 OAG43929.1 - 8.1e-155 515.7 0.0 1e-154 515.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_23 PF13489.6 OAG43929.1 - 1.8e-10 40.9 0.0 4.6e-09 36.3 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG43929.1 - 2.6e-10 40.9 0.0 1.2e-09 38.8 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG43929.1 - 1.2e-09 38.8 0.0 2.7e-08 34.5 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG43929.1 - 1.3e-09 38.6 0.0 8.3e-09 36.0 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAG43929.1 - 2.2e-08 33.8 0.0 4.7e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 OAG43929.1 - 2.6e-08 33.8 0.0 7.1e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 OAG43929.1 - 4.7e-07 29.8 0.0 8.4e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RNA_pol_I_TF PF04090.12 OAG43930.1 - 2e-06 27.4 0.5 1.1e-05 25.0 0.5 2.0 1 1 0 1 1 1 1 RNA polymerase I specific initiation factor zf-rbx1 PF12678.7 OAG43931.1 - 2.3e-09 37.4 0.5 4.2e-09 36.6 0.5 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 OAG43931.1 - 3.2e-09 37.0 0.8 5e-09 36.3 0.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 OAG43931.1 - 2.4e-06 27.3 1.0 4.1e-06 26.5 1.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAG43931.1 - 7.6e-06 25.7 0.4 1.3e-05 25.0 0.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 OAG43931.1 - 4.1e-05 23.1 0.9 6.7e-05 22.4 0.9 1.2 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 OAG43931.1 - 4.1e-05 23.6 0.1 6.9e-05 22.8 0.1 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 OAG43931.1 - 0.0003 20.6 0.2 0.00053 19.8 0.2 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 OAG43931.1 - 0.0012 18.8 0.2 0.002 18.1 0.2 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 OAG43931.1 - 0.0042 16.8 0.0 0.0073 16.0 0.0 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-Nse PF11789.8 OAG43931.1 - 0.036 13.9 0.8 0.067 13.0 0.8 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3H2C3 PF17122.5 OAG43931.1 - 0.047 13.7 1.9 0.085 12.9 1.9 1.4 1 0 0 1 1 1 0 Zinc-finger FANCL_C PF11793.8 OAG43931.1 - 0.058 13.6 0.4 0.11 12.7 0.4 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING_UBOX PF13445.6 OAG43931.1 - 0.07 13.2 0.6 0.16 12.1 0.6 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_3 PF13920.6 OAG43931.1 - 0.075 12.9 0.9 0.13 12.1 0.9 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 OAG43931.1 - 0.094 12.9 2.4 0.17 12.1 2.4 1.3 1 0 0 1 1 1 0 RING-variant domain zf-RING-like PF08746.11 OAG43931.1 - 0.69 10.3 2.6 1.1 9.6 2.6 1.3 1 0 0 1 1 1 0 RING-like domain Zn_clus PF00172.18 OAG43932.1 - 4.2e-07 30.0 12.0 7.3e-07 29.2 12.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 OAG43932.1 - 4.4e-07 29.1 0.0 8.3e-07 28.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF4698 PF15769.5 OAG43932.1 - 0.11 11.5 1.9 0.22 10.5 1.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4698) Reo_P9 PF06043.11 OAG43932.1 - 0.25 10.7 0.4 0.41 10.0 0.4 1.2 1 0 0 1 1 1 0 Reovirus P9-like family RAP1 PF07218.11 OAG43932.1 - 0.38 9.0 4.8 0.57 8.4 4.8 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) PAP_assoc PF03828.19 OAG43933.1 - 5.7e-10 39.3 0.1 1.4e-09 38.0 0.1 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 OAG43933.1 - 1.2e-07 32.0 0.0 2.6e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain FAT PF02259.23 OAG43934.1 - 1.3e-117 392.9 1.4 1.3e-117 392.9 1.4 2.1 2 1 1 3 3 3 1 FAT domain PI3_PI4_kinase PF00454.27 OAG43934.1 - 1.1e-73 248.2 0.4 3.8e-73 246.4 0.2 2.1 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.8 OAG43934.1 - 3.6e-62 209.0 4.3 6.3e-59 198.5 0.2 5.5 4 1 0 5 5 5 1 Domain of unknown function (DUF3385) FRB_dom PF08771.11 OAG43934.1 - 6.6e-42 141.9 2.7 8.9e-41 138.3 0.0 3.6 3 0 0 3 3 3 1 FKBP12-rapamycin binding domain HEAT_2 PF13646.6 OAG43934.1 - 1.7e-19 70.0 10.3 3.5e-05 24.1 0.1 9.3 7 2 1 9 9 8 5 HEAT repeats FATC PF02260.20 OAG43934.1 - 4.9e-16 58.3 0.2 2e-15 56.3 0.2 2.2 1 0 0 1 1 1 1 FATC domain HEAT_EZ PF13513.6 OAG43934.1 - 7.2e-12 45.5 13.6 1.1 9.9 0.0 11.3 10 1 2 12 12 11 3 HEAT-like repeat HEAT PF02985.22 OAG43934.1 - 9.1e-11 41.1 23.0 4.4 7.8 0.0 12.1 13 0 0 13 13 12 2 HEAT repeat TPR_19 PF14559.6 OAG43934.1 - 0.00061 20.3 0.2 4.3 7.9 0.0 5.3 5 0 0 5 5 4 1 Tetratricopeptide repeat MMS19_C PF12460.8 OAG43934.1 - 0.0044 16.2 5.8 0.44 9.6 0.1 4.8 3 2 1 4 4 4 1 RNAPII transcription regulator C-terminal CLASP_N PF12348.8 OAG43934.1 - 0.011 15.4 0.6 14 5.1 0.0 4.4 4 0 0 4 4 4 0 CLASP N terminal TPR_14 PF13428.6 OAG43934.1 - 0.015 16.1 4.0 16 6.6 0.1 5.1 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 OAG43934.1 - 0.054 13.2 0.1 0.22 11.2 0.1 2.1 1 0 0 1 1 1 0 TPR repeat Sec7_N PF12783.7 OAG43934.1 - 0.13 12.2 0.0 13 5.6 0.0 3.4 2 0 0 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal ANAPC3 PF12895.7 OAG43934.1 - 0.54 10.5 3.2 15 5.9 0.2 3.7 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 DAHP_synth_1 PF00793.20 OAG43935.1 - 3.2e-99 331.3 0.1 3.9e-99 331.0 0.1 1.0 1 0 0 1 1 1 1 DAHP synthetase I family COX14 PF14880.6 OAG43937.1 - 2e-12 46.8 0.0 2e-12 46.8 0.0 1.9 2 0 0 2 2 2 1 Cytochrome oxidase c assembly CobN-Mg_chel PF02514.16 OAG43937.1 - 0.00094 17.1 0.1 0.0011 16.9 0.1 1.0 1 0 0 1 1 1 1 CobN/Magnesium Chelatase NRIP1_repr_3 PF15689.5 OAG43937.1 - 0.52 10.6 3.2 0.96 9.8 1.2 2.3 2 1 1 3 3 3 0 Nuclear receptor-interacting protein 1 repression 3 SPX PF03105.19 OAG43937.1 - 1.7 8.5 6.1 2.7 7.8 6.1 1.3 1 1 0 1 1 1 0 SPX domain DUF2458 PF10454.9 OAG43938.1 - 1.1e-54 184.7 0.0 1.7e-54 184.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2458) BTB PF00651.31 OAG43939.1 - 3.6e-10 40.0 0.0 7.9e-10 39.0 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Zn_Tnp_IS1595 PF12760.7 OAG43939.1 - 0.073 13.1 4.2 0.19 11.8 4.2 1.7 1 1 0 1 1 1 0 Transposase zinc-ribbon domain ATG16 PF08614.11 OAG43939.1 - 4.5 7.4 30.1 12 6.0 30.2 1.6 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) RRM_1 PF00076.22 OAG43942.1 - 1.5e-09 37.5 0.0 3.6e-09 36.3 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 OAG43942.1 - 1.3e-07 31.5 0.0 2.6e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 OAG43942.1 - 0.0061 16.4 0.0 0.015 15.2 0.0 1.7 1 0 0 1 1 1 1 Occluded RNA-recognition motif RRM_3 PF08777.11 OAG43942.1 - 0.011 15.7 0.0 0.026 14.6 0.0 1.6 1 0 0 1 1 1 0 RNA binding motif DUF2235 PF09994.9 OAG43944.1 - 4.2e-52 177.3 0.0 5.9e-52 176.8 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) AA_permease_2 PF13520.6 OAG43945.1 - 4.4e-47 160.9 47.6 3.8e-45 154.5 39.9 2.1 2 0 0 2 2 2 2 Amino acid permease AA_permease PF00324.21 OAG43945.1 - 3.5e-21 75.3 31.8 3.5e-21 75.3 31.8 1.9 2 0 0 2 2 2 1 Amino acid permease DIE2_ALG10 PF04922.12 OAG43946.1 - 9e-119 397.3 13.6 1.3e-118 396.8 13.6 1.2 1 0 0 1 1 1 1 DIE2/ALG10 family Sld5 PF05916.11 OAG43947.1 - 2.4e-31 108.4 0.0 4.2e-31 107.6 0.0 1.4 1 0 0 1 1 1 1 GINS complex protein CUE PF02845.16 OAG43948.1 - 5.3e-08 32.4 0.0 8.1e-08 31.8 0.0 1.3 1 0 0 1 1 1 1 CUE domain DAG1 PF05454.11 OAG43948.1 - 0.0017 17.8 4.0 0.0031 16.9 4.0 1.4 1 0 0 1 1 1 1 Dystroglycan (Dystrophin-associated glycoprotein 1) G2BR PF18442.1 OAG43948.1 - 0.0049 16.5 13.1 0.0083 15.7 13.1 1.4 1 0 0 1 1 1 1 E3 gp78 Ube2g2-binding region (G2BR) SARAF PF06682.12 OAG43948.1 - 0.24 11.0 1.5 4.6 6.8 1.5 2.2 1 1 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis SH3_2 PF07653.17 OAG43949.1 - 1.1e-09 37.8 0.0 2e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 OAG43949.1 - 3e-09 36.3 0.2 6.8e-09 35.2 0.2 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 OAG43949.1 - 5.4e-08 32.6 0.2 1.3e-07 31.4 0.2 1.7 1 0 0 1 1 1 1 Variant SH3 domain RPAP2_Rtr1 PF04181.13 OAG43950.1 - 4.5e-21 74.9 0.0 8.1e-21 74.1 0.0 1.4 1 0 0 1 1 1 1 Rtr1/RPAP2 family DUF1077 PF06417.12 OAG43951.1 - 1.4e-21 76.7 0.1 1.6e-21 76.5 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) Adaptin_N PF01602.20 OAG43952.1 - 8.5e-119 397.5 10.8 1.1e-118 397.1 10.8 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 OAG43952.1 - 5e-54 182.7 8.8 5.7e-53 179.3 0.4 3.3 3 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 OAG43952.1 - 4.4e-14 52.6 5.8 8e-09 35.8 0.2 4.4 4 0 0 4 4 4 2 HEAT repeats HEAT PF02985.22 OAG43952.1 - 4.4e-09 35.8 5.4 0.02 15.1 0.0 5.8 7 0 0 7 7 7 3 HEAT repeat HEAT_EZ PF13513.6 OAG43952.1 - 0.00033 21.1 6.8 17 6.1 0.1 5.9 6 1 1 7 7 7 1 HEAT-like repeat CLASP_N PF12348.8 OAG43952.1 - 0.0047 16.5 1.4 11 5.6 0.0 3.6 3 1 0 3 3 3 2 CLASP N terminal Arm PF00514.23 OAG43952.1 - 0.0051 16.8 1.2 10 6.3 0.0 4.5 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 OAG43952.1 - 0.072 13.1 0.0 30 4.7 0.0 3.7 3 0 0 3 3 3 0 Spinocerebellar ataxia type 10 protein domain RasGEF_N_2 PF14663.6 OAG43952.1 - 0.074 13.5 2.2 10 6.6 0.0 3.8 4 0 0 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain FANCI_S2 PF14676.6 OAG43952.1 - 0.11 12.8 4.2 57 4.0 0.1 3.9 3 2 0 3 3 3 0 FANCI solenoid 2 GCV_T PF01571.21 OAG43953.1 - 1.2e-78 264.1 0.0 1.5e-78 263.7 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain CHD5 PF04420.14 OAG43953.1 - 7.2e-53 178.7 0.2 1.3e-52 177.8 0.2 1.5 1 0 0 1 1 1 1 CHD5-like protein GCV_T_C PF08669.11 OAG43953.1 - 1.4e-18 66.6 0.0 2.7e-18 65.6 0.0 1.6 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain YnfE PF17452.2 OAG43953.1 - 0.0066 16.7 0.0 0.013 15.7 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized YnfE-like Peptidase_S49_N PF08496.10 OAG43953.1 - 0.37 10.8 2.6 0.39 10.8 0.6 1.9 2 0 0 2 2 2 0 Peptidase family S49 N-terminal NDT80_PhoG PF05224.12 OAG43954.1 - 2.2e-36 125.8 0.0 3.2e-36 125.3 0.0 1.2 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family eIF3g PF12353.8 OAG43955.1 - 4.8e-41 140.0 4.3 8.4e-41 139.3 4.3 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 OAG43955.1 - 1e-14 54.1 0.0 2.3e-14 53.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH_7 PF18586.1 OAG43955.1 - 0.016 15.5 0.1 0.037 14.4 0.1 1.5 1 0 0 1 1 1 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 1 DUF4722 PF15849.5 OAG43956.1 - 0.0072 16.1 0.9 0.026 14.2 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4722) ATG16 PF08614.11 OAG43956.1 - 1.3 9.2 18.1 0.049 13.9 11.3 1.8 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Seryl_tRNA_N PF02403.22 OAG43956.1 - 2.7 8.3 9.3 0.89 9.8 4.6 2.4 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain KxDL PF10241.9 OAG43956.1 - 3 8.2 8.5 13 6.1 0.5 3.0 2 1 0 2 2 2 0 Uncharacterized conserved protein HSP70 PF00012.20 OAG43957.1 - 7.2e-12 44.3 0.0 2.5e-11 42.5 0.0 1.7 2 0 0 2 2 2 1 Hsp70 protein Orthopox_A47 PF06334.11 OAG43957.1 - 0.19 10.9 0.0 0.36 10.1 0.0 1.3 1 0 0 1 1 1 0 Orthopoxvirus A47 protein NMO PF03060.15 OAG43958.1 - 6.8e-56 190.0 0.3 9.8e-56 189.5 0.3 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 OAG43958.1 - 3.5e-11 42.7 0.2 9e-11 41.3 0.2 1.7 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 OAG43958.1 - 8.5e-06 25.0 0.9 1.5e-05 24.2 0.9 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase DHO_dh PF01180.21 OAG43958.1 - 0.00076 18.8 0.1 0.0014 17.9 0.1 1.5 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase Glu_synthase PF01645.17 OAG43958.1 - 0.0085 15.3 0.2 0.017 14.3 0.2 1.5 1 0 0 1 1 1 1 Conserved region in glutamate synthase Pterin_bind PF00809.22 OAG43959.1 - 4.6e-76 255.7 0.0 6.2e-76 255.3 0.0 1.2 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.20 OAG43959.1 - 6.4e-38 129.7 0.0 9.9e-37 125.9 0.0 2.3 2 0 0 2 2 2 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) MFS_1 PF07690.16 OAG43960.1 - 1.9e-49 168.5 10.4 1.2e-43 149.4 6.3 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 OAG43960.1 - 6.4e-08 31.3 0.1 0.00026 19.4 0.1 2.4 2 0 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family MFS_4 PF06779.14 OAG43960.1 - 0.0014 18.0 7.3 0.0014 18.0 7.3 2.4 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB LacY_symp PF01306.19 OAG43960.1 - 0.011 14.5 1.8 1.1 8.0 0.1 2.7 2 1 0 2 2 2 0 LacY proton/sugar symporter PUCC PF03209.15 OAG43960.1 - 0.038 13.0 11.6 0.17 10.8 7.1 3.0 2 1 0 2 2 2 0 PUCC protein MFS_1_like PF12832.7 OAG43960.1 - 0.076 11.9 10.7 0.12 11.2 3.8 3.4 3 1 1 4 4 4 0 MFS_1 like family DUF697 PF05128.12 OAG43960.1 - 0.089 12.5 2.6 0.19 11.4 1.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF697) TPR_12 PF13424.6 OAG43961.1 - 3.2e-12 46.6 5.0 3.5e-09 36.8 1.5 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat Clr5 PF14420.6 OAG43961.1 - 1.1e-06 28.8 4.9 1.1e-06 28.8 2.8 2.1 2 0 0 2 2 2 1 Clr5 domain TPR_10 PF13374.6 OAG43961.1 - 0.00014 21.6 2.6 0.048 13.6 0.8 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 OAG43961.1 - 0.00017 21.4 1.6 0.013 15.5 0.5 3.3 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 OAG43961.1 - 0.00021 21.2 0.7 0.05 13.8 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 OAG43961.1 - 0.0024 17.9 5.3 0.71 10.1 0.3 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 OAG43961.1 - 0.0057 17.4 6.3 0.68 10.9 0.3 3.9 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 OAG43961.1 - 0.015 15.1 0.2 0.41 10.5 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 OAG43961.1 - 0.1 12.3 0.2 0.46 10.2 0.1 2.1 2 0 0 2 2 2 0 TPR repeat SPA PF08616.10 OAG43961.1 - 0.11 12.5 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Stabilization of polarity axis TPR_16 PF13432.6 OAG43961.1 - 0.19 12.4 4.7 28 5.4 0.7 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 OAG43961.1 - 0.22 11.8 1.1 0.95 9.7 1.1 2.1 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 OAG43961.1 - 1.4 8.1 6.0 0.37 9.9 0.1 2.8 4 0 0 4 4 4 0 Tetratricopeptide repeat ORC4_C PF14629.6 OAG43962.1 - 3.7e-43 147.5 0.0 6.5e-43 146.6 0.0 1.4 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.6 OAG43962.1 - 6e-15 56.0 0.3 1.9e-14 54.4 0.3 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OAG43962.1 - 1.3e-05 25.5 0.0 5.7e-05 23.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 OAG43962.1 - 0.00016 22.1 0.0 0.00074 19.9 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 OAG43962.1 - 0.00032 20.7 0.0 0.0013 18.7 0.0 2.0 1 1 0 1 1 1 1 NACHT domain DUF815 PF05673.13 OAG43962.1 - 0.0028 16.9 0.0 0.0049 16.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) KAP_NTPase PF07693.14 OAG43962.1 - 0.018 14.3 0.0 0.041 13.1 0.0 1.6 1 0 0 1 1 1 0 KAP family P-loop domain ATPase_2 PF01637.18 OAG43962.1 - 0.036 14.0 0.0 0.086 12.7 0.0 1.6 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_5 PF07728.14 OAG43962.1 - 0.057 13.4 0.0 1.3 9.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 OAG43962.1 - 0.078 12.5 0.0 0.21 11.1 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region ThiS-like PF14453.6 OAG43962.1 - 0.086 12.9 0.0 0.21 11.7 0.0 1.7 1 0 0 1 1 1 0 ThiS-like ubiquitin ABC_tran PF00005.27 OAG43962.1 - 0.46 11.0 2.7 0.91 10.0 0.0 2.8 3 0 0 3 3 3 0 ABC transporter Sugar_tr PF00083.24 OAG43963.1 - 3.2e-79 266.9 15.5 3.6e-79 266.7 15.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG43963.1 - 6e-23 81.3 46.5 6e-21 74.7 23.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 OAG43963.1 - 0.00026 20.0 3.4 0.0005 19.1 3.4 1.4 1 0 0 1 1 1 1 MFS_1 like family Fungal_trans PF04082.18 OAG43964.1 - 6.1e-19 68.1 0.1 1.3e-18 67.0 0.1 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.6 OAG43964.1 - 2.1e-07 31.1 6.9 3.3e-06 27.3 0.9 2.7 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 OAG43964.1 - 0.00055 20.6 12.6 0.067 14.1 3.8 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.12 OAG43964.1 - 0.0085 16.4 4.1 0.016 15.4 4.1 1.4 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.26 OAG43964.1 - 0.0091 16.4 12.3 0.045 14.2 5.3 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 OAG43964.1 - 0.41 11.0 3.1 6.9 7.1 0.1 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding FAD_binding_7 PF03441.14 OAG43965.1 - 4e-55 186.4 1.7 6.4e-55 185.8 0.6 1.8 2 0 0 2 2 2 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 OAG43965.1 - 5.8e-41 140.2 0.0 1.5e-40 138.9 0.0 1.7 2 0 0 2 2 2 1 DNA photolyase zf-C3HC4_3 PF13920.6 OAG43966.1 - 0.0054 16.6 6.6 0.0089 15.9 6.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAG43966.1 - 0.011 15.7 2.1 0.025 14.6 2.1 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4 PF00097.25 OAG43966.1 - 0.014 15.2 3.4 0.029 14.2 3.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAG43966.1 - 0.015 15.2 4.1 0.031 14.3 4.1 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_6 PF14835.6 OAG43966.1 - 0.028 14.3 3.4 0.055 13.3 3.4 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C3HC4_2 PF13923.6 OAG43966.1 - 0.34 10.8 4.8 0.65 9.9 4.8 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Rhodanese_C PF12368.8 OAG43966.1 - 0.44 10.9 3.2 0.84 10.0 3.2 1.4 1 0 0 1 1 1 0 Rhodanase C-terminal zf-C3HC4_4 PF15227.6 OAG43966.1 - 0.49 10.6 2.5 1 9.5 2.5 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 OAG43966.1 - 1.1 9.1 5.4 2.2 8.2 5.4 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 OAG43966.1 - 1.1 9.6 6.7 2.3 8.6 6.7 1.6 1 0 0 1 1 1 0 Ring finger domain Ribosomal_S21 PF01165.20 OAG43967.1 - 1.7e-08 34.0 1.2 1.7e-08 34.0 1.2 1.8 2 0 0 2 2 2 1 Ribosomal protein S21 Rhodanese PF00581.20 OAG43968.1 - 1.1e-08 35.5 0.3 1.5e-07 31.9 0.3 2.1 1 1 0 1 1 1 1 Rhodanese-like domain THOC2_N PF16134.5 OAG43968.1 - 0.12 10.9 2.4 0.14 10.7 2.4 1.0 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus MscS_TM PF12794.7 OAG43968.1 - 5.4 5.8 7.7 7 5.4 7.7 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 DUF2079 PF09852.9 OAG43969.1 - 0.02 13.8 3.7 0.055 12.3 3.7 1.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2079) DUF805 PF05656.14 OAG43969.1 - 0.029 14.8 3.2 0.13 12.6 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF805) DuoxA PF10204.9 OAG43969.1 - 8.6 5.3 13.7 0.6 9.1 4.0 2.1 1 1 1 2 2 2 0 Dual oxidase maturation factor zf-MYND PF01753.18 OAG43970.1 - 1.2e-11 44.5 10.2 2e-11 43.8 10.2 1.4 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 OAG43970.1 - 1.7 9.0 11.5 8 6.9 11.5 2.1 1 1 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding PAD_porph PF04371.15 OAG43971.1 - 0.088 12.1 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Porphyromonas-type peptidyl-arginine deiminase Flag1_repress PF03614.13 OAG43971.1 - 0.1 12.4 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Repressor of phase-1 flagellin CN_hydrolase PF00795.22 OAG43972.1 - 2.3e-26 92.7 0.0 3.3e-26 92.2 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase LysR_substrate PF03466.20 OAG43972.1 - 0.09 12.1 0.0 8.5 5.7 0.0 2.2 2 0 0 2 2 2 0 LysR substrate binding domain Paf67 PF10255.9 OAG43973.1 - 2.2e-152 507.8 0.0 2.5e-152 507.6 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.17 OAG43973.1 - 0.04 14.0 0.0 0.25 11.5 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TRAPPC-Trs85 PF12739.7 OAG43973.1 - 0.04 12.9 0.1 0.057 12.4 0.1 1.3 1 0 0 1 1 1 0 ER-Golgi trafficking TRAPP I complex 85 kDa subunit Paf1 PF03985.13 OAG43974.1 - 1.8e-49 168.9 0.6 2.7e-49 168.3 0.6 1.2 1 0 0 1 1 1 1 Paf1 Paramyx_P_V_C PF03210.13 OAG43974.1 - 0.11 12.2 0.3 0.25 11.1 0.3 1.5 1 0 0 1 1 1 0 Paramyxovirus P/V phosphoprotein C-terminal Cyto_heme_lyase PF01265.17 OAG43975.1 - 1.4e-117 392.5 1.5 1.6e-117 392.3 1.5 1.0 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase Fungal_trans_2 PF11951.8 OAG43976.1 - 3.4e-06 26.1 0.0 2.6e-05 23.2 0.0 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Bac_surface_Ag PF01103.23 OAG43978.1 - 4e-43 148.1 1.2 8e-43 147.2 1.2 1.5 1 0 0 1 1 1 1 Surface antigen Yip1 PF04893.17 OAG43979.1 - 3.6e-05 23.6 15.9 0.00065 19.5 15.8 2.2 1 1 0 1 1 1 1 Yip1 domain DUF5134 PF17197.4 OAG43979.1 - 0.013 15.4 4.5 0.63 9.9 0.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF5134) HRI1 PF16815.5 OAG43980.1 - 8.2e-58 195.8 0.2 9.8e-58 195.6 0.2 1.1 1 0 0 1 1 1 1 Protein HRI1 Glyco_hydro_3_C PF01915.22 OAG43981.1 - 3.6e-64 216.5 0.0 6.5e-64 215.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 OAG43981.1 - 3.2e-47 161.5 0.0 5.1e-47 160.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 OAG43981.1 - 3e-24 84.9 0.5 8.8e-24 83.4 0.5 1.9 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 OAG43981.1 - 1e-10 41.6 0.0 2.4e-10 40.4 0.0 1.7 1 0 0 1 1 1 1 PA14 domain RCC1 PF00415.18 OAG43982.1 - 2.3e-19 69.7 17.0 0.0072 16.9 0.2 7.8 6 1 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OAG43982.1 - 5.7e-16 57.9 25.4 1.9e-05 24.3 0.1 6.6 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat Rad9 PF04139.13 OAG43983.1 - 3.4e-51 174.1 0.0 4e-51 173.9 0.0 1.1 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.16 OAG43983.1 - 1.3e-05 24.5 0.0 4.2e-05 22.7 0.0 1.9 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 DUF1326 PF07040.11 OAG43983.1 - 0.26 11.3 0.7 1.1 9.3 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1326) F-box-like PF12937.7 OAG43984.1 - 0.0046 16.8 1.0 0.011 15.6 0.0 2.2 2 0 0 2 2 2 1 F-box-like Aminotran_5 PF00266.19 OAG43985.1 - 1.8e-06 27.1 0.0 1.7e-05 23.9 0.0 1.9 2 0 0 2 2 2 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 OAG43985.1 - 0.051 12.1 0.0 0.072 11.6 0.0 1.1 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Aminotran_3 PF00202.21 OAG43985.1 - 0.13 10.9 0.0 0.21 10.2 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-III Fe-S_biosyn PF01521.20 OAG43986.1 - 2.2e-11 43.9 0.2 2.1e-10 40.8 0.2 2.1 1 1 0 1 1 1 1 Iron-sulphur cluster biosynthesis PCEMA1 PF07418.11 OAG43986.1 - 0.01 15.4 0.0 0.013 15.0 0.0 1.1 1 0 0 1 1 1 0 Acidic phosphoprotein precursor PCEMA1 DUF223 PF02721.14 OAG43986.1 - 0.026 14.8 0.2 0.05 13.9 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF223 DUF717 PF05338.12 OAG43987.1 - 0.0042 17.2 0.5 0.024 14.8 0.0 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF717) DUF3455 PF11937.8 OAG43987.1 - 0.08 13.3 0.1 0.15 12.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3455) Phasin_2 PF09361.10 OAG43987.1 - 0.19 12.0 4.4 7.2 6.9 0.1 3.4 3 1 0 3 3 3 0 Phasin protein PRKG1_interact PF15898.5 OAG43987.1 - 3 8.8 9.1 2.7 8.9 6.3 2.2 2 1 0 2 2 2 0 cGMP-dependent protein kinase interacting domain TRM PF02005.16 OAG43988.1 - 5.8e-106 354.8 0.0 6.5e-92 308.6 0.0 2.1 2 0 0 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.16 OAG43988.1 - 1.2e-05 25.2 0.0 2.6e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Met-10+ like-protein zf-C2H2_jaz PF12171.8 OAG43990.1 - 2.5e-06 27.6 3.3 6e-06 26.4 3.3 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OAG43990.1 - 0.011 16.1 0.8 0.022 15.1 0.8 1.6 1 0 0 1 1 1 0 Zinc-finger of C2H2 type HET PF06985.11 OAG43991.1 - 3.1e-10 40.6 5.1 5.3e-08 33.3 0.8 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) HALZ PF02183.18 OAG43992.1 - 0.00052 20.2 14.1 1.6 9.0 0.4 6.2 4 1 1 5 5 5 3 Homeobox associated leucine zipper Cnn_1N PF07989.11 OAG43992.1 - 0.0083 16.3 1.7 0.0083 16.3 1.7 6.7 4 3 3 7 7 7 2 Centrosomin N-terminal motif 1 Prp19 PF08606.11 OAG43992.1 - 0.044 13.8 0.2 0.044 13.8 0.2 3.2 3 0 0 3 3 3 0 Prp19/Pso4-like GIT_CC PF16559.5 OAG43992.1 - 0.12 12.3 13.0 0.97 9.3 0.5 5.6 4 2 0 5 5 5 0 GIT coiled-coil Rho guanine nucleotide exchange factor VAPB_antitox PF02697.14 OAG43992.1 - 3.3 8.5 13.8 0.3 11.9 1.2 4.8 2 1 3 5 5 5 0 Putative antitoxin DUF1691 PF07950.11 OAG43993.1 - 8.9e-32 110.0 2.6 1.9e-23 83.2 1.3 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1691) Transket_pyr PF02779.24 OAG43995.1 - 4.8e-49 166.4 0.0 7.7e-49 165.8 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 OAG43995.1 - 1e-33 115.9 0.0 2.3e-33 114.7 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain Metallophos PF00149.28 OAG43996.1 - 2.7e-09 37.8 1.4 6.3e-09 36.6 1.4 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase RNA_pol_inhib PF16857.5 OAG43997.1 - 0.026 14.3 0.0 0.052 13.3 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase inhibitor adh_short PF00106.25 OAG43998.1 - 3.1e-37 127.9 0.1 4.2e-37 127.5 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG43998.1 - 1e-26 94.0 0.0 1.3e-26 93.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG43998.1 - 0.00092 19.2 0.0 0.0015 18.5 0.0 1.2 1 0 0 1 1 1 1 KR domain Helicase_C PF00271.31 OAG43999.1 - 4.9e-14 52.6 0.0 1.3e-13 51.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HA2 PF04408.23 OAG43999.1 - 4.4e-11 43.0 0.6 1.6e-10 41.2 0.0 2.3 2 0 0 2 2 2 1 Helicase associated domain (HA2) DEAD PF00270.29 OAG43999.1 - 1.4e-09 38.0 0.1 2.5e-09 37.1 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 OAG43999.1 - 5.7e-05 23.5 0.1 0.00014 22.2 0.1 1.6 1 0 0 1 1 1 1 AAA domain Abhydrolase_1 PF00561.20 OAG44000.1 - 1.3e-16 61.0 0.0 1.9e-09 37.5 0.0 3.4 3 1 1 4 4 4 3 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG44000.1 - 1.7e-11 45.1 0.0 3.6e-11 44.1 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG44000.1 - 2.1e-08 33.7 0.0 4.6e-05 22.8 0.0 3.1 3 0 0 3 3 3 2 Serine aminopeptidase, S33 Ndr PF03096.14 OAG44000.1 - 0.15 10.7 0.0 2.8 6.6 0.0 2.1 2 0 0 2 2 2 0 Ndr family Actin PF00022.19 OAG44001.1 - 1.1e-29 103.3 0.0 2e-18 66.2 0.0 2.8 2 1 0 2 2 2 2 Actin MreB_Mbl PF06723.13 OAG44001.1 - 3.1e-07 29.5 0.1 0.0002 20.3 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein Actin_micro PF17003.5 OAG44001.1 - 1.5e-05 24.4 0.7 2.5e-05 23.6 0.2 1.5 2 0 0 2 2 2 1 Putative actin-like family PilM_2 PF11104.8 OAG44001.1 - 6.7e-05 22.1 0.2 0.023 13.8 0.0 2.2 2 0 0 2 2 2 2 Type IV pilus assembly protein PilM; FtsA PF14450.6 OAG44001.1 - 7.3e-05 23.1 0.0 0.00025 21.4 0.0 2.0 2 1 0 2 2 2 1 Cell division protein FtsA Arf PF00025.21 OAG44002.1 - 3.3e-63 212.3 0.1 1.2e-46 158.3 0.0 2.0 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 OAG44002.1 - 3.7e-10 40.1 0.0 1.2e-09 38.4 0.0 1.7 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 OAG44002.1 - 1.4e-07 31.0 0.1 3.6e-06 26.4 0.0 2.2 1 1 1 2 2 2 1 G-protein alpha subunit SRPRB PF09439.10 OAG44002.1 - 6.9e-06 25.6 0.0 9.7e-05 21.9 0.0 2.0 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 OAG44002.1 - 1.1e-05 25.1 0.0 2e-05 24.2 0.0 1.5 1 1 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 OAG44002.1 - 6.2e-05 22.5 0.0 9.5e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OAG44002.1 - 0.009 16.1 0.0 0.03 14.4 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase MeaB PF03308.16 OAG44002.1 - 0.11 11.5 0.1 0.34 9.9 0.1 1.7 1 1 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Peptidase_M3 PF01432.20 OAG44003.1 - 2.3e-160 534.8 0.3 4.2e-160 534.0 0.1 1.5 2 0 0 2 2 2 1 Peptidase family M3 AF0941-like PF14591.6 OAG44003.1 - 0.34 11.5 0.1 0.34 11.5 0.1 2.4 3 0 0 3 3 3 0 AF0941-like MFS_1 PF07690.16 OAG44004.1 - 6.5e-16 58.2 16.3 1.5e-15 57.0 13.6 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TauD PF02668.16 OAG44005.1 - 1.4e-57 195.5 0.3 2.1e-57 195.0 0.3 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family ATG_C PF09333.11 OAG44005.1 - 0.12 12.7 0.0 0.36 11.2 0.0 1.7 2 0 0 2 2 2 0 Autophagy-related protein C terminal domain Proteasome PF00227.26 OAG44006.1 - 1.1e-55 188.1 0.0 1.4e-55 187.7 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 OAG44006.1 - 1.6e-12 46.9 0.2 3.6e-12 45.7 0.0 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature GCP_N_terminal PF17681.1 OAG44007.1 - 1.1e-64 219.1 0.0 1.6e-64 218.5 0.0 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 OAG44007.1 - 5.3e-53 180.5 1.2 8.5e-53 179.8 1.2 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal Methyltransf_8 PF05148.15 OAG44009.1 - 3.9e-54 183.8 0.0 1.5e-51 175.4 0.0 3.0 3 1 0 3 3 3 2 Hypothetical methyltransferase Methyltransf_11 PF08241.12 OAG44009.1 - 0.00044 20.8 0.0 0.003 18.2 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG44009.1 - 0.016 15.9 0.0 0.1 13.3 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain DUF3328 PF11807.8 OAG44009.1 - 0.1 12.3 0.1 0.19 11.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) Fungal_trans_2 PF11951.8 OAG44010.1 - 7.2e-18 64.5 0.9 1.6e-17 63.5 0.9 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain GDI PF00996.18 OAG44012.1 - 2.9e-190 632.4 0.0 3.4e-190 632.2 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.6 OAG44012.1 - 0.0061 16.8 0.0 0.016 15.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain TPP_enzyme_N PF02776.18 OAG44013.1 - 1e-31 109.8 0.5 1.6e-31 109.2 0.5 1.2 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 OAG44013.1 - 1e-18 67.4 0.0 3.1e-18 65.8 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 OAG44013.1 - 8.5e-15 54.9 0.1 1.7e-14 53.8 0.1 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain adh_short_C2 PF13561.6 OAG44014.1 - 9.4e-61 205.3 0.7 1.1e-60 205.2 0.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG44014.1 - 3.6e-45 153.8 0.6 4.5e-45 153.5 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG44014.1 - 2.8e-09 37.1 0.1 3.6e-09 36.8 0.1 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 OAG44015.1 - 1.4e-06 28.4 0.0 2.2e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAG44015.1 - 9.8e-06 25.2 0.0 0.0045 16.5 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NmrA PF05368.13 OAG44015.1 - 0.00019 21.0 0.0 0.003 17.1 0.0 2.3 2 0 0 2 2 2 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 OAG44015.1 - 0.062 13.6 0.2 0.13 12.6 0.0 1.6 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain DXP_reductoisom PF02670.16 OAG44015.1 - 0.16 12.7 0.0 4.4 8.0 0.0 2.6 2 1 1 3 3 3 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase MRP-L47 PF06984.13 OAG44016.1 - 7.2e-16 58.1 0.2 1.3e-15 57.2 0.2 1.4 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) DUF4577 PF15145.6 OAG44016.1 - 0.056 13.5 0.0 0.083 12.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4577) Prok-E2_A PF14457.6 OAG44016.1 - 0.14 11.7 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family A SMC_N PF02463.19 OAG44017.1 - 9.3e-71 237.7 0.0 2.4e-70 236.4 0.0 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 OAG44017.1 - 4.4e-22 78.6 1.7 1e-20 74.2 0.2 3.1 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 OAG44017.1 - 1.5e-10 41.4 0.9 0.00066 19.6 0.0 3.4 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran PF00005.27 OAG44017.1 - 0.00023 21.7 0.0 0.00023 21.7 0.0 6.5 5 2 0 5 5 5 2 ABC transporter AAA_29 PF13555.6 OAG44017.1 - 0.0012 18.6 0.1 0.0028 17.4 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain GAS PF13851.6 OAG44017.1 - 0.0028 17.0 11.1 0.0028 17.0 11.1 7.3 3 2 5 8 8 8 3 Growth-arrest specific micro-tubule binding Cnn_1N PF07989.11 OAG44017.1 - 0.013 15.7 7.5 0.013 15.7 7.5 10.7 4 3 7 11 11 11 0 Centrosomin N-terminal motif 1 RACo_C_ter PF14574.6 OAG44017.1 - 0.4 9.7 7.8 5 6.1 0.1 2.5 2 0 0 2 2 2 0 C-terminal domain of RACo the ASKHA domain Mce4_CUP1 PF11887.8 OAG44017.1 - 4 6.8 8.3 2.5 7.5 2.3 3.2 2 1 0 3 3 3 0 Cholesterol uptake porter CUP1 of Mce4, putative TIM PF00121.18 OAG44018.1 - 2.1e-35 122.2 0.0 3e-34 118.5 0.0 2.1 1 1 0 1 1 1 1 Triosephosphate isomerase LacAB_rpiB PF02502.18 OAG44019.1 - 1.5e-44 151.4 0.4 1.7e-44 151.2 0.4 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase Gly_rich_SFCGS PF14272.6 OAG44019.1 - 0.0053 16.8 0.0 0.0081 16.2 0.0 1.4 1 1 0 1 1 1 1 Glycine-rich SFCGS DUF2620 PF10941.8 OAG44019.1 - 0.034 14.3 0.5 0.056 13.6 0.5 1.5 1 1 0 1 1 1 0 Protein of unknown function DUF2620 DUF2781 PF10914.8 OAG44020.1 - 3.3e-30 105.4 17.8 7.7e-30 104.2 17.8 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF2781) DUF2569 PF10754.9 OAG44020.1 - 0.078 13.4 4.4 0.58 10.6 1.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2569) Nucleoporin_N PF08801.11 OAG44021.1 - 6e-93 311.9 0.1 8.1e-93 311.5 0.1 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 OAG44021.1 - 6.6e-56 190.3 3.5 4.3e-55 187.6 3.4 1.9 1 1 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal MutS_III PF05192.18 OAG44021.1 - 0.11 12.7 0.1 0.93 9.7 0.0 2.2 2 0 0 2 2 2 0 MutS domain III YqeY PF09424.10 OAG44022.1 - 1.5e-14 54.3 6.6 1.8e-14 54.1 6.6 1.1 1 0 0 1 1 1 1 Yqey-like protein Chalcone_3 PF16036.5 OAG44022.1 - 0.054 13.6 0.5 0.66 10.1 0.5 1.9 1 1 1 2 2 2 0 Chalcone isomerase-like DUF3072 PF11272.8 OAG44022.1 - 0.57 10.1 2.8 2.1 8.3 1.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3072) Peptidase_S9 PF00326.21 OAG44023.1 - 5.7e-52 176.3 0.0 1e-51 175.4 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family PD40 PF07676.12 OAG44023.1 - 0.00041 20.2 0.0 0.12 12.3 0.0 3.2 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat AXE1 PF05448.12 OAG44023.1 - 0.0027 16.4 0.6 0.18 10.4 0.2 2.6 2 1 0 2 2 2 1 Acetyl xylan esterase (AXE1) Amidohydro_1 PF01979.20 OAG44024.1 - 7e-14 51.9 0.3 1.2e-12 47.8 0.3 2.1 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 OAG44024.1 - 8.3e-09 35.4 0.2 7.9e-06 25.6 0.1 2.3 2 0 0 2 2 2 2 Amidohydrolase family Pol_alpha_B_N PF08418.10 OAG44024.1 - 0.11 12.5 0.2 0.17 11.8 0.2 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal MFS_1 PF07690.16 OAG44025.1 - 1.4e-18 66.9 28.9 2.4e-18 66.2 28.9 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 OAG44025.1 - 3.1e-11 43.2 6.8 3.1e-11 43.2 6.8 3.0 4 1 0 4 4 4 1 Ion channel regulatory protein UNC-93 MFS_1_like PF12832.7 OAG44025.1 - 0.00054 18.9 8.1 0.00054 18.9 8.1 2.7 1 1 2 3 3 3 1 MFS_1 like family DUF676 PF05057.14 OAG44026.1 - 1.1e-40 139.5 0.3 6.7e-26 91.2 0.0 3.6 4 0 0 4 4 4 3 Putative serine esterase (DUF676) FMN_dh PF01070.18 OAG44027.1 - 8.7e-119 396.6 0.0 1e-118 396.3 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 OAG44027.1 - 6.3e-24 83.9 0.0 1.4e-23 82.8 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 OAG44027.1 - 2.4e-09 36.8 0.0 4.3e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 OAG44027.1 - 4.1e-05 22.8 0.4 0.00021 20.4 0.1 2.0 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 OAG44027.1 - 0.0014 18.0 0.1 0.0019 17.7 0.1 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase ThiG PF05690.14 OAG44027.1 - 0.033 13.5 0.1 6.3 6.0 0.1 2.3 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 OAG44027.1 - 0.059 12.8 1.0 0.82 9.1 0.1 2.2 1 1 0 2 2 2 0 Histidine biosynthesis protein AA_permease PF00324.21 OAG44028.1 - 1e-140 469.6 34.8 1.1e-140 469.4 34.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAG44028.1 - 6.6e-37 127.4 37.8 8.3e-37 127.0 37.8 1.1 1 0 0 1 1 1 1 Amino acid permease SpoIIIAH PF12685.7 OAG44028.1 - 0.0011 18.8 5.0 0.0019 18.1 5.0 1.3 1 0 0 1 1 1 1 SpoIIIAH-like protein Nop14 PF04147.12 OAG44028.1 - 0.0012 17.2 33.5 0.0016 16.8 33.5 1.1 1 0 0 1 1 1 1 Nop14-like family NPR3 PF03666.13 OAG44028.1 - 0.0034 16.2 5.4 0.0048 15.7 5.4 1.1 1 0 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 BUD22 PF09073.10 OAG44028.1 - 0.018 14.4 30.3 0.026 13.9 30.3 1.2 1 0 0 1 1 1 0 BUD22 DUF913 PF06025.12 OAG44028.1 - 0.022 13.8 1.5 0.033 13.2 1.5 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) TFIIF_alpha PF05793.12 OAG44028.1 - 0.027 13.1 33.4 0.04 12.5 33.4 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF4781 PF16013.5 OAG44028.1 - 0.054 12.3 0.1 0.087 11.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4781) CDC45 PF02724.14 OAG44028.1 - 0.14 10.4 25.6 0.28 9.4 25.6 1.4 1 0 0 1 1 1 0 CDC45-like protein DDHD PF02862.17 OAG44028.1 - 0.18 12.0 0.9 0.31 11.2 0.9 1.3 1 0 0 1 1 1 0 DDHD domain Afi1 PF07792.12 OAG44028.1 - 0.28 11.7 14.2 0.55 10.7 14.2 1.4 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Serinc PF03348.15 OAG44028.1 - 0.29 10.0 5.3 0.64 8.9 0.0 2.5 2 0 0 2 2 2 0 Serine incorporator (Serinc) Cwf_Cwc_15 PF04889.12 OAG44028.1 - 0.55 9.9 30.3 0.96 9.1 30.3 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF2052 PF09747.9 OAG44028.1 - 0.64 10.1 30.3 1.4 9.0 30.3 1.5 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) RRN3 PF05327.11 OAG44028.1 - 0.9 8.0 20.9 1.3 7.4 20.9 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Mpp10 PF04006.12 OAG44028.1 - 0.93 7.9 37.6 1.4 7.3 37.6 1.1 1 0 0 1 1 1 0 Mpp10 protein SpoIIP PF07454.11 OAG44028.1 - 1.1 8.7 11.8 1.6 8.1 11.8 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF4637 PF15470.6 OAG44028.1 - 1.3 8.7 26.9 3.3 7.4 26.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) CPSF100_C PF13299.6 OAG44028.1 - 2 8.6 16.1 0.43 10.7 12.8 1.5 2 0 0 2 2 1 0 Cleavage and polyadenylation factor 2 C-terminal Paf1 PF03985.13 OAG44028.1 - 2.4 7.1 34.5 3.5 6.5 34.5 1.1 1 0 0 1 1 1 0 Paf1 CNDH2_C PF16858.5 OAG44028.1 - 4.6 7.0 18.8 7.5 6.3 18.8 1.2 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term DUF2457 PF10446.9 OAG44028.1 - 4.8 6.2 46.5 8.9 5.3 46.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Tim54 PF11711.8 OAG44028.1 - 5.7 5.6 16.1 9.6 4.9 16.1 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF5523 PF17661.1 OAG44028.1 - 7.4 6.2 28.4 14 5.2 28.4 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5523) RNA_pol_Rpc4 PF05132.14 OAG44028.1 - 7.8 6.9 11.8 17 5.8 11.8 1.5 1 0 0 1 1 1 0 RNA polymerase III RPC4 Nrap_D5 PF17406.2 OAG44029.1 - 1.2e-56 191.0 0.3 2.2e-56 190.1 0.3 1.4 1 0 0 1 1 1 1 Nrap protein PAP/OAS1-like domain 5 Nrap_D4 PF17405.2 OAG44029.1 - 3.3e-49 167.1 0.0 7.4e-49 166.0 0.0 1.6 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D3 PF17404.2 OAG44029.1 - 2.8e-42 144.5 0.0 5.5e-42 143.6 0.0 1.4 1 0 0 1 1 1 1 Nrap protein domain 3 Nrap_D2 PF17403.2 OAG44029.1 - 6.2e-39 133.2 0.0 4.9e-36 123.8 0.0 2.4 2 0 0 2 2 2 2 Nrap protein PAP/OAS-like domain Nrap_D6 PF17407.2 OAG44029.1 - 3.3e-38 130.9 0.0 7e-38 129.9 0.0 1.6 1 0 0 1 1 1 1 Nrap protein domain 6 Nrap PF03813.14 OAG44029.1 - 1.5e-28 99.8 0.0 3.1e-28 98.7 0.0 1.6 1 0 0 1 1 1 1 Nrap protein domain 1 HARP PF07443.13 OAG44029.1 - 0.063 12.9 0.0 2.5 7.8 0.0 3.0 3 0 0 3 3 3 0 HepA-related protein (HARP) Mito_carr PF00153.27 OAG44030.1 - 3.5e-53 177.5 2.6 4.8e-22 77.7 0.3 4.0 4 0 0 4 4 4 4 Mitochondrial carrier protein SMC_N PF02463.19 OAG44031.1 - 8.1e-26 90.8 0.0 1.6e-25 89.9 0.0 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 OAG44031.1 - 1.9e-10 41.0 2.1 1.9e-10 41.0 2.1 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 OAG44031.1 - 5.7e-09 36.8 34.0 5.7e-09 36.8 34.0 5.2 2 2 0 2 2 2 1 AAA domain AAA_21 PF13304.6 OAG44031.1 - 2.5e-07 30.8 0.4 0.0037 17.1 0.3 2.9 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 OAG44031.1 - 0.00097 18.8 0.0 0.0022 17.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain DEAD PF00270.29 OAG44032.1 - 3.1e-42 144.3 0.0 4.7e-42 143.7 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAG44032.1 - 9.3e-29 100.0 0.9 2.6e-27 95.3 0.3 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG44032.1 - 0.00041 20.4 0.0 0.00096 19.2 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit API5 PF05918.11 OAG44032.1 - 0.038 12.8 7.8 0.054 12.3 7.8 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) CMS1 PF14617.6 OAG44032.1 - 0.092 12.1 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit DUF1918 PF08940.11 OAG44033.1 - 0.0059 16.2 0.1 2.3 7.9 0.1 4.1 4 0 0 4 4 4 1 Domain of unknown function (DUF1918) I-set PF07679.16 OAG44033.1 - 0.18 11.9 0.0 14 5.8 0.0 3.6 3 0 0 3 3 3 0 Immunoglobulin I-set domain Peptidase_C12 PF01088.21 OAG44034.1 - 4.6e-50 170.3 0.0 8.1e-50 169.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 YccV-like PF08755.11 OAG44034.1 - 3e-25 88.6 0.3 6.6e-25 87.5 0.3 1.6 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like Transglut_core2 PF13369.6 OAG44034.1 - 2e-13 50.2 0.0 4.1e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily F-box-like PF12937.7 OAG44034.1 - 8.2e-10 38.4 0.1 1.8e-09 37.3 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAG44034.1 - 2.4e-07 30.5 0.0 4.9e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 F-box domain Syd PF07348.12 OAG44035.1 - 0.1 12.2 0.3 0.21 11.3 0.0 1.6 2 0 0 2 2 2 0 Syd protein (SUKH-2) Rhodanese PF00581.20 OAG44037.1 - 1.7e-06 28.5 0.0 2.6e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain DnaJ PF00226.31 OAG44039.1 - 3.1e-23 81.7 0.5 3.1e-23 81.7 0.5 2.2 2 0 0 2 2 2 1 DnaJ domain zf-C2H2_jaz PF12171.8 OAG44039.1 - 6e-13 48.7 15.6 2.8e-10 40.2 4.2 3.6 2 1 1 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OAG44039.1 - 4.9e-11 42.6 9.8 2.7e-09 37.1 2.2 3.4 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 OAG44039.1 - 2e-08 34.5 6.5 0.0012 19.1 2.0 2.5 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 OAG44039.1 - 2e-06 28.1 3.9 0.03 15.1 0.3 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 OAG44039.1 - 9e-06 25.9 6.7 0.014 15.8 0.8 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type MIT_C PF16565.5 OAG44039.1 - 0.15 12.0 0.2 0.36 10.8 0.2 1.6 1 0 0 1 1 1 0 Phospholipase D-like domain at C-terminus of MIT zf-C2H2_6 PF13912.6 OAG44039.1 - 0.3 11.1 8.0 2.5 8.2 0.5 2.8 3 0 0 3 3 3 0 C2H2-type zinc finger CpXC PF14353.6 OAG44039.1 - 0.42 10.7 5.8 0.28 11.3 0.2 2.8 3 0 0 3 3 3 0 CpXC protein ABM PF03992.16 OAG44039.1 - 0.44 10.7 4.8 0.94 9.6 1.8 3.0 2 1 0 2 2 2 0 Antibiotic biosynthesis monooxygenase zf-LYAR PF08790.11 OAG44039.1 - 1.9 8.5 4.7 1.6 8.7 1.0 2.5 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger SPX PF03105.19 OAG44040.1 - 3.4e-48 165.5 9.1 1.5e-47 163.3 9.1 2.0 1 1 0 1 1 1 1 SPX domain zf-C3HC4_3 PF13920.6 OAG44040.1 - 3.7e-08 33.1 7.8 6.7e-08 32.3 7.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OAG44040.1 - 1.2e-07 31.7 11.5 1.3e-07 31.6 9.3 2.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 OAG44040.1 - 9.9e-07 28.5 9.3 2.4e-06 27.3 9.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAG44040.1 - 4.2e-05 23.4 7.7 0.00012 22.0 7.8 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 OAG44040.1 - 4.6e-05 23.2 10.2 0.00014 21.6 10.2 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAG44040.1 - 8.1e-05 22.6 7.0 0.00051 20.0 7.4 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 OAG44040.1 - 0.00015 22.0 11.0 0.00039 20.7 11.0 1.7 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 OAG44040.1 - 0.00091 19.0 8.8 0.0046 16.8 9.2 2.0 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 DivIC PF04977.15 OAG44040.1 - 0.0087 15.8 3.4 5.9 6.7 0.5 3.9 3 0 0 3 3 3 1 Septum formation initiator zf-RING_4 PF14570.6 OAG44040.1 - 0.011 15.6 2.8 0.011 15.6 2.8 1.9 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 OAG44040.1 - 0.076 13.1 2.3 0.15 12.2 2.3 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Erythro_esteras PF05139.14 OAG44040.1 - 0.14 11.9 2.8 0.27 11.0 2.8 1.4 1 0 0 1 1 1 0 Erythromycin esterase SlyX PF04102.12 OAG44040.1 - 0.19 12.3 6.0 3.3 8.4 0.3 3.4 3 0 0 3 3 3 0 SlyX TerY_C PF15616.6 OAG44040.1 - 0.25 11.4 3.7 0.52 10.4 2.9 1.8 1 1 1 2 2 2 0 TerY-C metal binding domain zf-rbx1 PF12678.7 OAG44040.1 - 0.29 11.5 6.6 0.89 9.9 6.6 1.9 1 0 0 1 1 1 0 RING-H2 zinc finger domain NOB1_Zn_bind PF08772.11 OAG44040.1 - 1.2 9.3 4.7 0.77 10.0 2.2 2.0 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like ADH_N PF08240.12 OAG44041.1 - 2.3e-05 24.2 0.0 0.00012 21.9 0.0 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG44041.1 - 0.0029 17.6 0.1 0.0078 16.2 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Sacchrp_dh_NADP PF03435.18 OAG44041.1 - 0.14 12.5 0.1 0.2 11.9 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 OAG44042.1 - 4.1e-12 46.1 0.0 6.1e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 OAG44042.1 - 1.3e-07 31.4 0.2 0.015 14.9 0.1 2.4 2 1 0 2 2 2 2 NmrA-like family GDP_Man_Dehyd PF16363.5 OAG44042.1 - 0.0028 17.1 0.0 1.5 8.2 0.0 2.2 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 OAG44042.1 - 0.0081 15.3 0.1 0.093 11.8 0.0 2.1 2 0 0 2 2 2 1 RmlD substrate binding domain adh_short PF00106.25 OAG44042.1 - 0.009 15.5 0.2 0.024 14.1 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase PHB_acc_N PF07879.11 OAG44042.1 - 0.11 12.6 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 PHB/PHA accumulation regulator DNA-binding domain 3-dmu-9_3-mt PF06983.13 OAG44044.1 - 2.7e-35 121.4 0.2 4.3e-35 120.8 0.2 1.2 1 0 0 1 1 1 1 3-demethylubiquinone-9 3-methyltransferase Ntox35 PF15534.6 OAG44044.1 - 0.37 11.2 2.3 0.5 10.8 0.4 1.9 2 0 0 2 2 2 0 Bacterial toxin 35 NAD_binding_2 PF03446.15 OAG44045.1 - 1.1e-32 113.4 0.1 1.5e-32 112.9 0.1 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 OAG44045.1 - 7.2e-29 100.5 0.0 1.3e-28 99.7 0.0 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 2-Hacid_dh_C PF02826.19 OAG44045.1 - 2.3e-07 30.4 0.0 3.7e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 OAG44045.1 - 2.9e-05 24.5 0.4 9.8e-05 22.9 0.0 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.12 OAG44045.1 - 0.0031 17.1 0.0 0.005 16.4 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain Rossmann-like PF10727.9 OAG44045.1 - 0.0058 16.5 0.1 0.018 14.9 0.0 1.8 2 0 0 2 2 2 1 Rossmann-like domain SUFU PF05076.13 OAG44045.1 - 0.012 15.6 0.0 0.025 14.6 0.0 1.5 1 1 0 1 1 1 0 Suppressor of fused protein (SUFU) TrkA_N PF02254.18 OAG44045.1 - 0.13 12.6 0.0 0.37 11.1 0.0 1.8 1 1 0 1 1 1 0 TrkA-N domain Shikimate_DH PF01488.20 OAG44045.1 - 0.14 12.3 0.0 0.28 11.3 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 OAG44046.1 - 9.9e-15 54.6 0.0 1.8e-14 53.7 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 OAG44046.1 - 6.1e-07 29.0 1.0 0.00037 19.8 0.2 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAG44046.1 - 2.1e-05 23.8 0.3 3.4e-05 23.1 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 OAG44046.1 - 2.4e-05 24.5 0.2 5.4e-05 23.3 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 OAG44046.1 - 0.0007 18.8 0.3 0.0011 18.1 0.3 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A DAO PF01266.24 OAG44046.1 - 0.00072 19.2 0.2 0.0087 15.7 0.2 2.2 1 1 1 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 OAG44046.1 - 0.047 14.3 0.2 2.1 8.9 0.4 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 OAG44046.1 - 0.06 12.7 0.4 0.095 12.0 0.4 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase IlvN PF07991.12 OAG44046.1 - 0.08 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain MREG PF15812.5 OAG44046.1 - 0.085 13.2 0.1 0.37 11.1 0.1 2.0 2 0 0 2 2 2 0 Melanoregulin HI0933_like PF03486.14 OAG44046.1 - 0.12 11.1 0.3 0.39 9.4 0.5 1.7 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_3 PF13738.6 OAG44046.1 - 0.21 10.8 0.1 0.47 9.7 0.2 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_4 PF01565.23 OAG44047.1 - 1.1e-28 99.7 0.0 2e-28 98.9 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.19 OAG44047.1 - 2.3e-09 37.3 0.0 3.7e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FMN_dh PF01070.18 OAG44048.1 - 6.3e-111 370.8 0.0 8.2e-111 370.4 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 OAG44048.1 - 2.7e-19 69.1 0.0 6.2e-19 67.9 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Fungal_trans PF04082.18 OAG44048.1 - 4.6e-06 25.9 0.1 3e-05 23.2 0.1 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Glu_synthase PF01645.17 OAG44048.1 - 0.013 14.7 0.0 0.021 14.0 0.0 1.2 1 0 0 1 1 1 0 Conserved region in glutamate synthase IMPDH PF00478.25 OAG44048.1 - 0.19 10.7 0.0 0.31 10.0 0.0 1.3 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain ECH_1 PF00378.20 OAG44049.1 - 3.5e-45 154.3 0.4 4.2e-45 154.0 0.4 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAG44049.1 - 7.7e-23 81.5 0.6 1e-22 81.1 0.6 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 OAG44049.1 - 0.067 13.1 1.8 1.1 9.2 0.2 2.5 2 1 1 3 3 3 0 Peptidase family S49 ADH_zinc_N PF00107.26 OAG44050.1 - 3.1e-20 72.5 0.8 7.7e-20 71.2 0.3 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG44050.1 - 8.9e-20 70.6 1.0 1.5e-19 69.8 1.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 OAG44050.1 - 1.7e-06 27.7 0.7 3.2e-06 26.8 0.7 1.4 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 OAG44050.1 - 1.7e-05 25.9 0.0 3.2e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 OAG44050.1 - 0.00082 18.7 1.5 0.00082 18.7 1.5 1.6 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 OAG44050.1 - 0.077 12.4 0.1 0.13 11.6 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ECH_1 PF00378.20 OAG44051.1 - 1.3e-39 136.0 0.0 1.6e-39 135.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAG44051.1 - 4.1e-16 59.4 0.0 4.5e-16 59.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase adh_short_C2 PF13561.6 OAG44052.1 - 7.5e-36 123.8 0.1 1.1e-35 123.3 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG44052.1 - 3.4e-26 91.9 0.0 4.6e-26 91.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG44052.1 - 9.7e-05 22.4 0.2 0.00022 21.2 0.2 1.5 1 1 0 1 1 1 1 KR domain AMP-binding PF00501.28 OAG44053.1 - 2.5e-70 237.2 0.0 3.3e-70 236.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG44053.1 - 8.3e-13 49.1 0.0 1.6e-12 48.2 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Acyl-CoA_dh_1 PF00441.24 OAG44054.1 - 2.6e-28 99.1 0.4 3.6e-28 98.7 0.4 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 OAG44054.1 - 4.7e-20 71.6 0.1 7.8e-20 70.9 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 OAG44054.1 - 2.7e-14 53.8 0.0 7.6e-14 52.3 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 OAG44054.1 - 0.00028 21.2 0.8 0.00045 20.5 0.8 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Aldedh PF00171.22 OAG44055.1 - 4.4e-52 177.1 0.0 5.9e-52 176.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family MFS_1 PF07690.16 OAG44056.1 - 1.2e-17 63.9 45.9 1.9e-17 63.2 42.1 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 OAG44056.1 - 1e-15 57.2 24.2 2.4e-15 56.0 24.3 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Fungal_trans PF04082.18 OAG44057.1 - 3.3e-06 26.3 0.3 5.9e-06 25.5 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain ECH_1 PF00378.20 OAG44058.1 - 7.9e-25 87.6 0.0 3.1e-14 52.9 0.0 2.1 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAG44058.1 - 8.3e-10 38.7 0.1 3.7e-05 23.4 0.0 2.5 2 1 1 3 3 3 2 Enoyl-CoA hydratase/isomerase LRAT PF04970.13 OAG44058.1 - 0.093 13.0 0.0 0.17 12.2 0.0 1.3 1 0 0 1 1 1 0 Lecithin retinol acyltransferase But2 PF09792.9 OAG44060.1 - 6.6e-13 49.3 1.1 7e-13 49.2 0.0 1.5 2 0 0 2 2 2 1 Ubiquitin 3 binding protein But2 C-terminal domain PepSY_like PF11396.8 OAG44061.1 - 0.13 12.8 0.9 0.35 11.5 0.2 1.9 2 0 0 2 2 2 0 Putative beta-lactamase-inhibitor-like, PepSY-like Aminotran_1_2 PF00155.21 OAG44062.1 - 7.3e-39 134.0 0.0 9.6e-39 133.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 OAG44062.1 - 0.00036 19.2 0.0 0.00062 18.4 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Glucan_synthase PF02364.15 OAG44063.1 - 0 1398.2 0.0 0 1397.5 0.0 1.3 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 OAG44063.1 - 1.4e-43 148.3 0.6 4.2e-43 146.8 0.6 1.9 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Glyco_hydro_72 PF03198.14 OAG44064.1 - 8.3e-138 458.9 7.3 1e-137 458.6 7.3 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 OAG44064.1 - 4.9e-22 78.4 2.6 1.7e-21 76.7 2.6 1.9 1 0 0 1 1 1 1 X8 domain Glyco_hydro_114 PF03537.13 OAG44064.1 - 0.044 13.1 3.2 1.6 8.0 0.1 2.3 1 1 1 2 2 2 0 Glycoside-hydrolase family GH114 Mog1 PF04603.12 OAG44065.1 - 8.3e-28 97.5 0.1 3.9e-27 95.3 0.1 2.1 1 1 0 1 1 1 1 Ran-interacting Mog1 protein DUF3446 PF11928.8 OAG44065.1 - 1 9.7 18.5 0.68 10.3 8.7 2.6 2 0 0 2 2 2 0 Early growth response N-terminal domain SPX PF03105.19 OAG44065.1 - 1.8 8.4 4.7 2.1 8.2 4.7 1.1 1 0 0 1 1 1 0 SPX domain SR-25 PF10500.9 OAG44065.1 - 1.9 8.1 7.4 3 7.4 7.4 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein AP3B1_C PF14796.6 OAG44065.1 - 2.1 8.6 7.6 0.54 10.5 1.3 2.3 2 0 0 2 2 2 0 Clathrin-adaptor complex-3 beta-1 subunit C-terminal TMEM154 PF15102.6 OAG44065.1 - 2.9 7.8 13.4 4.1 7.3 6.1 2.2 2 0 0 2 2 2 0 TMEM154 protein family Mucin PF01456.17 OAG44065.1 - 5.6 7.0 30.7 1.3 9.0 17.5 2.3 2 0 0 2 2 2 0 Mucin-like glycoprotein SprT-like PF10263.9 OAG44066.1 - 1.8e-37 127.7 0.3 3.2e-37 126.9 0.3 1.4 1 0 0 1 1 1 1 SprT-like family Zn_ribbon_SprT PF17283.2 OAG44066.1 - 2.2e-07 30.7 4.8 4.2e-07 29.7 1.7 2.5 2 0 0 2 2 2 1 SprT-like zinc ribbon domain SPT6_acidic PF14632.6 OAG44066.1 - 1.2 9.8 17.0 0.058 14.0 6.9 3.0 2 0 0 2 2 2 0 Acidic N-terminal SPT6 p450 PF00067.22 OAG44067.1 - 1.7e-58 198.5 0.0 1.9e-58 198.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ArsB PF02040.15 OAG44069.1 - 6.9e-11 42.1 9.7 1.5e-05 24.6 3.5 2.1 2 0 0 2 2 2 2 Arsenical pump membrane protein DUF4267 PF14087.6 OAG44070.1 - 1.4e-24 86.3 6.1 1.8e-24 86.0 6.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) zf-C2H2 PF00096.26 OAG44072.1 - 4.5e-06 26.8 11.3 0.0032 17.8 1.5 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OAG44072.1 - 0.00029 21.1 4.1 0.00029 21.1 4.1 2.2 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 OAG44072.1 - 0.00066 20.3 10.4 0.052 14.4 2.6 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_5 PF13909.6 OAG44072.1 - 0.41 10.4 3.5 2.4 8.0 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc-finger domain COG5 PF10392.9 OAG44074.1 - 7.3e-29 100.6 2.2 1.6e-28 99.5 2.2 1.6 1 0 0 1 1 1 1 Golgi transport complex subunit 5 COX6B PF02297.17 OAG44075.1 - 1.8e-23 82.5 3.0 2.5e-23 82.1 3.0 1.2 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb CLU PF13236.6 OAG44075.1 - 0.067 13.0 0.0 0.09 12.6 0.0 1.2 1 1 0 1 1 1 0 Clustered mitochondria SYS1 PF09801.9 OAG44076.1 - 4.3e-52 176.1 7.2 5e-52 175.9 7.2 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network VIT1 PF01988.19 OAG44076.1 - 0.32 10.8 5.5 0.19 11.6 4.0 1.4 1 1 0 1 1 1 0 VIT family Epimerase PF01370.21 OAG44077.1 - 2.7e-11 43.4 0.1 1.7e-10 40.7 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 OAG44077.1 - 7.9e-10 38.9 0.1 1.2e-09 38.3 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 OAG44077.1 - 3.9e-05 23.3 0.2 0.00032 20.3 0.1 2.0 2 0 0 2 2 2 1 NmrA-like family 3Beta_HSD PF01073.19 OAG44077.1 - 7.8e-05 21.8 0.0 0.00068 18.7 0.0 2.1 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Shikimate_DH PF01488.20 OAG44077.1 - 0.00013 22.0 0.0 0.00021 21.4 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase GDP_Man_Dehyd PF16363.5 OAG44077.1 - 0.00013 21.4 0.0 0.0017 17.8 0.0 2.3 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase AlaDh_PNT_C PF01262.21 OAG44077.1 - 0.0017 17.7 0.2 0.0027 17.0 0.2 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.16 OAG44077.1 - 0.003 17.2 0.1 0.005 16.5 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 OAG44077.1 - 0.01 16.1 0.1 0.017 15.4 0.1 1.3 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_2 PF03446.15 OAG44077.1 - 0.016 15.4 0.0 0.025 14.8 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Seipin PF06775.14 OAG44077.1 - 0.088 12.9 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 Putative adipose-regulatory protein (Seipin) Polysacc_synt_2 PF02719.15 OAG44077.1 - 0.093 11.8 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Get5_bdg PF16843.5 OAG44077.1 - 0.17 11.4 0.1 0.36 10.3 0.1 1.5 1 0 0 1 1 1 0 Binding domain to Get4 on Get5, Golgi to ER traffic protein DnaJ PF00226.31 OAG44078.1 - 5.2e-21 74.5 2.2 1.4e-20 73.1 0.7 2.5 2 0 0 2 2 2 1 DnaJ domain TPR_2 PF07719.17 OAG44078.1 - 3.6e-11 42.3 11.1 0.042 14.0 0.0 8.2 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_9 PF13371.6 OAG44078.1 - 4.3e-11 42.8 4.4 0.0018 18.4 0.1 5.0 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 OAG44078.1 - 9.5e-10 37.9 5.4 0.0036 17.1 0.0 7.1 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_19 PF14559.6 OAG44078.1 - 1.8e-06 28.3 7.0 0.061 13.8 0.0 5.1 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 OAG44078.1 - 2.8e-06 27.7 15.5 2.7 9.1 0.0 6.3 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 OAG44078.1 - 6.3e-06 25.8 0.0 0.26 11.0 0.1 4.3 3 1 1 4 4 4 3 TPR repeat TPR_8 PF13181.6 OAG44078.1 - 2.2e-05 24.3 2.4 0.45 10.9 0.0 6.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_16 PF13432.6 OAG44078.1 - 4.9e-05 23.9 23.9 0.31 11.7 0.1 6.6 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_6 PF13174.6 OAG44078.1 - 5e-05 23.7 11.7 3.8 8.4 0.0 7.1 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_17 PF13431.6 OAG44078.1 - 0.00085 19.5 0.1 1.8 9.1 0.0 4.4 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 OAG44078.1 - 0.0073 16.5 10.6 0.38 11.0 0.3 4.6 4 2 1 5 5 4 2 Anaphase-promoting complex, cyclosome, subunit 3 PknG_TPR PF16918.5 OAG44078.1 - 0.01 14.6 0.3 0.042 12.6 0.1 2.1 2 1 0 2 2 2 0 Protein kinase G tetratricopeptide repeat HrpB1_HrpK PF09613.10 OAG44078.1 - 0.05 13.2 0.8 0.33 10.6 0.0 2.5 2 1 0 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) Toprim_3 PF13362.6 OAG44078.1 - 0.076 13.4 4.1 0.065 13.6 1.2 2.5 2 1 0 2 2 2 0 Toprim domain MOZ_SAS PF01853.18 OAG44079.1 - 1.6e-53 181.1 0.0 7.1e-53 178.9 0.0 1.9 1 1 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 OAG44079.1 - 4.4e-11 42.2 1.6 4.7e-06 26.1 0.0 2.6 2 0 0 2 2 2 2 MYST family zinc finger domain Macoilin PF09726.9 OAG44080.1 - 5.1 5.5 9.0 7.2 5.0 9.0 1.2 1 0 0 1 1 1 0 Macoilin family Prefoldin PF02996.17 OAG44081.1 - 1.3e-24 86.4 1.3 3.4e-20 72.1 0.0 2.8 3 0 0 3 3 3 2 Prefoldin subunit Sec2p PF06428.11 OAG44081.1 - 0.00019 21.3 1.0 0.14 12.2 0.0 2.3 2 0 0 2 2 2 2 GDP/GTP exchange factor Sec2p Prefoldin_2 PF01920.20 OAG44081.1 - 0.0022 17.9 1.6 0.045 13.7 0.0 2.6 2 1 0 2 2 2 1 Prefoldin subunit YscO PF07321.12 OAG44081.1 - 0.01 15.8 3.2 0.03 14.3 0.1 2.2 2 0 0 2 2 2 0 Type III secretion protein YscO DUF4201 PF13870.6 OAG44081.1 - 0.016 14.9 1.4 2.2 8.0 0.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) DHR10 PF18595.1 OAG44081.1 - 0.029 14.4 2.0 0.27 11.3 0.3 2.2 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain HAUS6_N PF14661.6 OAG44081.1 - 0.037 13.6 0.6 0.051 13.2 0.1 1.4 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus DUF4795 PF16043.5 OAG44081.1 - 0.038 13.6 1.0 1.8 8.1 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) Laminin_II PF06009.12 OAG44081.1 - 0.11 12.5 0.9 0.25 11.3 0.2 1.7 2 0 0 2 2 2 0 Laminin Domain II DUF1664 PF07889.12 OAG44081.1 - 0.13 12.3 0.5 18 5.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Phage_TAC_3 PF06896.11 OAG44081.1 - 0.17 12.5 2.3 3.9 8.1 0.1 2.5 1 1 1 2 2 2 0 Phage tail assembly chaperone proteins, TAC THOC7 PF05615.13 OAG44081.1 - 0.26 11.6 2.8 7 6.9 1.5 2.1 2 0 0 2 2 2 0 Tho complex subunit 7 Fzo_mitofusin PF04799.13 OAG44081.1 - 0.32 10.5 2.2 0.39 10.3 0.8 1.7 2 0 0 2 2 2 0 fzo-like conserved region Spc7 PF08317.11 OAG44081.1 - 0.55 9.0 5.1 6 5.6 0.1 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein ABC_tran_CTD PF16326.5 OAG44082.1 - 0.2 11.9 17.5 0.45 10.8 2.2 3.1 3 0 0 3 3 3 0 ABC transporter C-terminal domain GAS PF13851.6 OAG44082.1 - 0.79 9.0 19.4 1.4 8.2 19.4 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding AAA_23 PF13476.6 OAG44082.1 - 0.84 10.1 7.0 1.9 9.0 7.0 1.5 1 0 0 1 1 1 0 AAA domain DUF4407 PF14362.6 OAG44082.1 - 0.97 8.7 5.1 1.9 7.7 5.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4140 PF13600.6 OAG44082.1 - 1.1 9.8 7.7 1.4 9.4 2.3 2.9 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) KfrA_N PF11740.8 OAG44082.1 - 3.6 8.3 7.3 7.5 7.3 0.2 3.0 3 0 0 3 3 3 0 Plasmid replication region DNA-binding N-term zf-MIZ PF02891.20 OAG44084.1 - 1.3e-11 44.0 0.8 3.5e-11 42.7 0.8 1.8 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 OAG44084.1 - 0.00018 21.2 0.1 0.00039 20.2 0.1 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit DUF3525 PF12039.8 OAG44084.1 - 0.038 12.7 0.0 0.061 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3525) SAM_2 PF07647.17 OAG44085.1 - 9.5e-13 48.1 0.3 3.1e-12 46.4 0.1 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) PH PF00169.29 OAG44085.1 - 1.1e-10 41.9 0.0 5.4e-10 39.7 0.0 2.1 1 1 0 1 1 1 1 PH domain SH3_1 PF00018.28 OAG44085.1 - 1.1e-08 34.6 0.0 2.1e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 OAG44085.1 - 2.3e-07 30.6 0.1 5.9e-07 29.3 0.1 1.7 2 0 0 2 2 2 1 Variant SH3 domain SAM_1 PF00536.30 OAG44085.1 - 0.00077 19.9 0.1 0.0017 18.7 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH_11 PF15413.6 OAG44085.1 - 0.0097 16.3 0.0 0.028 14.9 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain SH3_2 PF07653.17 OAG44085.1 - 0.019 14.7 0.0 0.042 13.5 0.0 1.6 1 0 0 1 1 1 0 Variant SH3 domain 14-3-3 PF00244.20 OAG44088.1 - 5.4e-100 333.5 5.8 6.3e-100 333.2 5.8 1.0 1 0 0 1 1 1 1 14-3-3 protein Imm71 PF15602.6 OAG44088.1 - 0.028 14.5 0.4 0.58 10.2 0.0 2.2 1 1 1 2 2 2 0 Immunity protein 71 FapA PF03961.13 OAG44088.1 - 0.03 12.9 1.1 0.038 12.6 1.1 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A IATP PF04568.12 OAG44089.1 - 1.3e-25 89.7 4.2 1.5e-25 89.5 4.2 1.0 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP PKHD_C PF18331.1 OAG44089.1 - 0.0016 18.4 0.3 0.0045 17.0 0.2 1.7 2 0 0 2 2 2 1 PKHD-type hydroxylase C-terminal domain BLOC1_2 PF10046.9 OAG44089.1 - 0.0032 17.7 1.3 0.0044 17.3 1.3 1.2 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF489 PF04356.12 OAG44089.1 - 0.055 13.5 0.0 0.06 13.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF489) TssO PF17561.2 OAG44089.1 - 0.061 13.4 0.7 0.076 13.1 0.7 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssO DivIC PF04977.15 OAG44089.1 - 0.092 12.5 2.2 0.15 11.9 2.2 1.3 1 0 0 1 1 1 0 Septum formation initiator Glutaredoxin2_C PF04399.13 OAG44089.1 - 0.11 12.4 0.3 0.15 11.9 0.3 1.2 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain Nsp1_C PF05064.13 OAG44090.1 - 1.7e-31 108.4 2.6 1.9e-31 108.3 0.4 1.9 2 0 0 2 2 2 1 Nsp1-like C-terminal region AAA_13 PF13166.6 OAG44090.1 - 0.17 10.5 1.1 0.49 9.0 1.1 1.6 1 1 0 1 1 1 0 AAA domain HAP1_N PF04849.13 OAG44090.1 - 0.97 8.6 6.3 0.2 10.8 0.6 2.0 2 0 0 2 2 2 0 HAP1 N-terminal conserved region MIP-T3_C PF17749.1 OAG44090.1 - 4.3 7.3 6.4 42 4.1 0.1 3.1 2 1 0 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region DUF5102 PF17104.5 OAG44091.1 - 4.5e-110 368.3 2.4 4.5e-110 368.3 2.4 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF5102) Fungal_trans PF04082.18 OAG44092.1 - 5.3e-06 25.7 0.0 8.1e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain MRP-S33 PF08293.11 OAG44092.1 - 0.11 12.7 0.0 0.34 11.2 0.0 1.8 2 0 0 2 2 2 0 Mitochondrial ribosomal subunit S27 MFS_1 PF07690.16 OAG44093.1 - 2e-32 112.5 39.4 2e-32 112.5 39.4 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 OAG44093.1 - 8.7e-05 21.5 27.5 0.00025 20.1 12.1 2.1 1 1 0 2 2 2 2 MFS_1 like family CSN8_PSD8_EIF3K PF10075.9 OAG44094.1 - 4.3e-19 68.9 0.0 2.4e-18 66.5 0.0 1.9 2 0 0 2 2 2 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 OAG44094.1 - 0.0029 17.0 0.0 0.0097 15.3 0.0 1.7 2 0 0 2 2 2 1 SAC3/GANP family F-box_4 PF15966.5 OAG44096.1 - 0.011 15.6 0.1 0.028 14.3 0.1 1.6 1 0 0 1 1 1 0 F-box F-box-like PF12937.7 OAG44096.1 - 0.057 13.3 0.2 0.14 12.0 0.2 1.7 1 0 0 1 1 1 0 F-box-like WD40 PF00400.32 OAG44097.1 - 1e-26 92.6 0.1 2e-08 34.7 0.1 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG44097.1 - 3.2e-11 43.4 0.0 0.00087 19.5 0.0 4.6 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 OAG44097.1 - 0.0065 15.8 0.0 0.29 10.4 0.0 2.5 1 1 1 2 2 2 1 WD40-like domain PQQ_2 PF13360.6 OAG44097.1 - 0.012 15.2 0.3 0.37 10.3 0.0 2.3 1 1 1 2 2 2 0 PQQ-like domain PALB2_WD40 PF16756.5 OAG44097.1 - 0.11 11.3 0.0 2.7 6.8 0.0 2.1 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain Ge1_WD40 PF16529.5 OAG44097.1 - 0.12 11.3 0.3 3.6 6.4 0.0 2.8 2 1 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 OAG44097.1 - 0.15 10.7 0.1 0.61 8.7 0.1 1.9 1 1 1 2 2 2 0 Nucleoporin Nup120/160 FTHFS PF01268.19 OAG44098.1 - 4.1e-255 847.2 0.0 5.8e-255 846.7 0.0 1.2 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 OAG44098.1 - 4.9e-67 224.2 0.7 4.9e-67 224.2 0.7 2.1 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 OAG44098.1 - 5.3e-40 136.3 0.5 1.3e-39 135.1 0.5 1.7 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain OCD_Mu_crystall PF02423.15 OAG44098.1 - 0.0049 15.8 0.3 0.012 14.6 0.0 1.6 2 0 0 2 2 2 1 Ornithine cyclodeaminase/mu-crystallin family GTP_EFTU PF00009.27 OAG44098.1 - 0.035 13.6 0.2 0.11 12.1 0.0 1.9 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Fungal_trans PF04082.18 OAG44099.1 - 5.1e-16 58.5 0.0 8.4e-16 57.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain EHN PF06441.12 OAG44100.1 - 1.1e-31 109.4 0.8 2.1e-31 108.5 0.8 1.5 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 OAG44100.1 - 3.6e-13 49.7 0.0 6.7e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold CorA PF01544.18 OAG44100.1 - 3.4e-05 23.3 0.1 8.8e-05 22.0 0.1 1.7 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF915 PF06028.11 OAG44100.1 - 0.11 11.8 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Gar1 PF04410.14 OAG44101.1 - 5.7e-37 126.9 0.0 7.8e-37 126.4 0.0 1.2 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region CDP-OH_P_transf PF01066.21 OAG44101.1 - 7.1e-13 49.1 0.2 1.7e-12 47.9 0.2 1.7 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase tRNA-synt_2b PF00587.25 OAG44102.1 - 1e-31 110.3 0.0 1.4e-28 100.0 0.0 2.8 3 0 0 3 3 3 2 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 OAG44102.1 - 2.9e-16 59.4 0.2 6.4e-16 58.3 0.2 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.14 OAG44102.1 - 7.7e-12 45.1 0.0 1.5e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.21 OAG44102.1 - 1.3e-05 25.2 0.0 0.00026 21.0 0.0 2.4 2 0 0 2 2 2 1 TGS domain DUF2370 PF10176.9 OAG44103.1 - 1.5e-89 299.6 0.0 2.6e-89 298.8 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2370) DUF2561 PF10812.8 OAG44103.1 - 0.27 11.2 1.4 0.38 10.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2561) Abhydrolase_6 PF12697.7 OAG44105.1 - 3.8e-05 24.4 0.7 5.3e-05 23.9 0.7 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF4054 PF13262.6 OAG44105.1 - 0.071 13.1 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4054) Peptidase_S9 PF00326.21 OAG44105.1 - 0.099 12.1 0.0 5.8 6.3 0.0 2.4 2 0 0 2 2 2 0 Prolyl oligopeptidase family RRM_1 PF00076.22 OAG44106.1 - 1.6e-09 37.5 0.0 3.1e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OAG44106.1 - 3.3e-05 23.5 0.0 6.8e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GET2 PF08690.10 OAG44106.1 - 0.0068 16.1 3.1 0.0068 16.1 3.1 2.6 3 1 0 3 3 3 1 GET complex subunit GET2 DbpA PF03880.15 OAG44106.1 - 0.11 12.5 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 DbpA RNA binding domain U3_assoc_6 PF08640.11 OAG44107.1 - 9.6e-30 102.5 0.8 2.3e-27 94.9 0.4 2.4 2 0 0 2 2 2 2 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.6 OAG44107.1 - 3.5e-05 24.3 4.2 0.05 14.5 0.1 4.4 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_15 PF13429.6 OAG44107.1 - 0.044 13.0 0.1 0.077 12.2 0.1 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat NRDE-2 PF08424.10 OAG44107.1 - 0.1 11.7 0.0 0.51 9.4 0.0 1.9 1 1 0 1 1 1 0 NRDE-2, necessary for RNA interference Frag1 PF10277.9 OAG44108.1 - 6.8e-40 136.9 8.0 6.8e-40 136.9 8.0 3.2 3 0 0 3 3 3 2 Frag1/DRAM/Sfk1 family Methyltransf_2 PF00891.18 OAG44110.1 - 3.4e-24 85.3 0.5 1.6e-23 83.1 0.2 2.1 2 1 0 2 2 2 1 O-methyltransferase domain Rrf2 PF02082.20 OAG44110.1 - 0.004 17.5 0.0 0.015 15.6 0.0 2.0 2 0 0 2 2 2 1 Transcriptional regulator Dimerisation2 PF16864.5 OAG44110.1 - 0.031 14.2 0.0 0.068 13.2 0.0 1.5 1 0 0 1 1 1 0 Dimerisation domain MarR_2 PF12802.7 OAG44110.1 - 0.14 12.0 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 MarR family FMO-like PF00743.19 OAG44111.1 - 2.2e-19 69.3 0.0 7.5e-17 60.9 0.0 2.5 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OAG44111.1 - 1.3e-11 44.6 0.0 4.2e-11 42.9 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 OAG44111.1 - 6e-07 28.9 0.0 0.022 13.9 0.0 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 OAG44111.1 - 8.2e-07 28.6 0.0 2e-05 24.0 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAG44111.1 - 9.4e-06 25.1 0.0 0.2 10.8 0.0 2.8 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAG44111.1 - 0.0013 18.0 0.0 0.0051 16.1 0.0 1.8 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.6 OAG44111.1 - 0.0074 16.3 0.1 0.052 13.5 0.0 2.4 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.24 OAG44111.1 - 0.0076 15.9 0.0 0.41 10.2 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 OAG44111.1 - 0.049 12.7 0.0 0.48 9.5 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A HI0933_like PF03486.14 OAG44111.1 - 0.13 11.0 0.0 0.28 9.8 0.0 1.6 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.27 OAG44111.1 - 0.13 12.8 0.2 2.5 8.7 0.0 2.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Fungal_trans PF04082.18 OAG44112.1 - 3.4e-24 85.3 0.1 5.1e-24 84.7 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 OAG44113.1 - 6.3e-35 120.7 24.8 3.2e-34 118.4 25.9 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily p450 PF00067.22 OAG44114.1 - 5.2e-61 206.8 0.0 3.7e-52 177.6 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 ADH_N PF08240.12 OAG44115.1 - 1.6e-06 28.0 0.1 2.1e-05 24.4 0.1 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ACOX PF01756.19 OAG44116.1 - 7.4e-36 123.4 0.0 1.5e-35 122.4 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 OAG44116.1 - 2.3e-24 86.3 0.2 3.9e-24 85.6 0.2 1.4 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 OAG44116.1 - 4.3e-11 42.9 0.0 9.3e-11 41.8 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 OAG44116.1 - 0.00019 21.7 0.4 0.042 14.1 0.0 2.4 2 0 0 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain FAD_binding_4 PF01565.23 OAG44117.1 - 1.3e-21 76.8 1.2 2.6e-21 75.8 1.2 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 OAG44117.1 - 5.3e-08 32.8 0.1 1.6e-07 31.3 0.1 1.8 2 0 0 2 2 2 1 Berberine and berberine like SH2_2 PF14633.6 OAG44118.1 - 9.4e-85 283.4 0.0 9.4e-85 283.4 0.0 1.9 2 0 0 2 2 2 1 SH2 domain HTH_44 PF14641.6 OAG44118.1 - 1e-31 109.7 0.2 4.4e-31 107.7 0.2 2.2 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 HHH_7 PF14635.6 OAG44118.1 - 2.5e-29 101.7 0.0 5e-29 100.7 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.6 OAG44118.1 - 1.2e-25 90.0 0.0 4.7e-25 88.1 0.0 2.1 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 SPT6_acidic PF14632.6 OAG44118.1 - 2.4e-15 56.9 30.8 2.4e-15 56.9 30.8 6.0 4 1 3 7 7 7 1 Acidic N-terminal SPT6 HHH_9 PF17674.1 OAG44118.1 - 3.3e-06 27.9 6.7 5e-06 27.3 1.9 3.6 2 1 0 2 2 2 1 HHH domain SH2 PF00017.24 OAG44118.1 - 1.7e-05 24.8 0.0 4.6e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 SH2 domain HHH_3 PF12836.7 OAG44118.1 - 0.009 16.3 0.0 0.023 14.9 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif Pkinase PF00069.25 OAG44119.1 - 2.3e-63 214.0 0.0 2.9e-63 213.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG44119.1 - 4.7e-34 117.8 0.0 6.8e-34 117.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAG44119.1 - 7.1e-05 21.8 0.0 0.00011 21.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 OAG44119.1 - 0.00022 20.7 0.0 0.00037 19.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 OAG44119.1 - 0.034 13.2 0.0 0.05 12.7 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 OAG44119.1 - 0.12 12.2 0.0 0.28 11.1 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 OAG44119.1 - 0.22 11.1 0.0 0.38 10.3 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Haspin_kinase PF12330.8 OAG44119.1 - 0.24 10.3 0.0 0.37 9.7 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain VHS PF00790.19 OAG44120.1 - 1.4e-43 148.1 0.0 2.9e-43 147.1 0.0 1.6 1 0 0 1 1 1 1 VHS domain Alpha_adaptinC2 PF02883.20 OAG44120.1 - 3.1e-23 82.2 0.8 6.8e-23 81.1 0.8 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain GAT PF03127.14 OAG44120.1 - 3.1e-20 72.3 0.0 8.8e-20 70.8 0.0 1.9 1 0 0 1 1 1 1 GAT domain GGA_N-GAT PF18308.1 OAG44120.1 - 9.6e-09 34.7 0.4 1.2e-06 28.0 0.0 3.2 3 0 0 3 3 3 1 GGA N-GAT domain Rootletin PF15035.6 OAG44121.1 - 8.1 6.4 8.1 35 4.3 4.8 2.5 2 1 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion CBS PF00571.28 OAG44122.1 - 5.9e-15 55.4 8.2 1.5e-05 25.3 0.0 5.1 5 0 0 5 5 5 3 CBS domain SGL PF08450.12 OAG44124.1 - 4.4e-22 78.9 0.2 7.6e-22 78.1 0.2 1.5 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 OAG44124.1 - 3.3e-05 24.0 0.1 0.001 19.2 0.1 2.8 2 1 1 3 3 3 1 Arylesterase Str_synth PF03088.16 OAG44124.1 - 4.5e-05 23.5 0.0 0.00023 21.2 0.0 2.1 1 1 0 1 1 1 1 Strictosidine synthase Pep_deformylase PF01327.21 OAG44125.1 - 1.9e-41 141.3 0.0 2.8e-41 140.8 0.0 1.3 1 1 0 1 1 1 1 Polypeptide deformylase AtuA PF07287.11 OAG44126.1 - 6.7e-129 429.6 0.2 8.1e-129 429.3 0.2 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA ADH_zinc_N PF00107.26 OAG44127.1 - 2e-23 82.8 0.1 3.8e-23 81.9 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG44127.1 - 5e-22 77.9 1.3 1.1e-21 76.8 1.3 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 OAG44127.1 - 4.8e-06 26.0 4.2 1.1e-05 24.9 3.8 1.7 1 1 1 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 OAG44127.1 - 7.2e-05 22.2 0.3 0.00022 20.6 0.2 1.7 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.6 OAG44127.1 - 0.00011 23.3 0.1 0.00047 21.2 0.1 2.0 1 1 0 1 1 1 1 Zinc-binding dehydrogenase 3HCDH_N PF02737.18 OAG44127.1 - 0.0026 17.6 1.8 0.0051 16.7 1.8 1.5 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ThiF PF00899.21 OAG44127.1 - 0.0086 15.5 0.2 0.0086 15.5 0.2 1.6 2 0 0 2 2 2 1 ThiF family adh_short PF00106.25 OAG44127.1 - 0.012 15.1 1.8 0.019 14.4 1.2 1.6 1 1 0 1 1 1 0 short chain dehydrogenase Pyr_redox_2 PF07992.14 OAG44127.1 - 0.016 14.4 0.1 0.031 13.5 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase XdhC_C PF13478.6 OAG44127.1 - 0.067 13.7 0.1 0.11 13.0 0.1 1.4 1 0 0 1 1 1 0 XdhC Rossmann domain LIM PF00412.22 OAG44127.1 - 0.079 13.2 0.9 0.18 12.1 0.9 1.5 1 0 0 1 1 1 0 LIM domain TrkA_N PF02254.18 OAG44127.1 - 0.091 13.0 0.6 0.15 12.3 0.6 1.4 1 0 0 1 1 1 0 TrkA-N domain UDPG_MGDP_dh_N PF03721.14 OAG44127.1 - 0.15 11.7 0.1 0.25 10.9 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Aldedh PF00171.22 OAG44128.1 - 1.2e-157 525.1 0.2 1.4e-157 524.9 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 OAG44128.1 - 0.0034 16.9 0.2 0.02 14.4 0.2 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) Chromosome_seg PF13889.6 OAG44128.1 - 0.051 13.7 0.0 0.16 12.1 0.0 1.8 2 0 0 2 2 2 0 Chromosome segregation during meiosis NTP_transf_4 PF13562.6 OAG44128.1 - 0.18 12.0 0.0 0.36 11.0 0.0 1.4 1 0 0 1 1 1 0 Sugar nucleotidyl transferase DUF3425 PF11905.8 OAG44129.1 - 8.1e-25 87.2 0.2 8.1e-25 87.2 0.2 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 OAG44129.1 - 4.4 7.5 8.8 15 5.8 8.9 1.8 1 1 1 2 2 2 0 bZIP transcription factor FMO-like PF00743.19 OAG44130.1 - 9.1e-14 50.8 0.1 3.1e-11 42.4 0.1 2.4 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OAG44130.1 - 1.4e-11 44.4 0.0 6.1e-11 42.4 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 OAG44130.1 - 7.6e-08 32.0 0.0 4.2e-06 26.2 0.0 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG44130.1 - 2.9e-06 26.7 0.0 0.00082 18.6 0.0 2.9 2 1 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 OAG44130.1 - 3.5e-05 23.2 0.0 0.0024 17.2 0.0 2.2 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAG44130.1 - 9e-05 22.5 0.0 0.0021 18.1 0.0 3.0 4 0 0 4 4 4 1 FAD-NAD(P)-binding DAO PF01266.24 OAG44130.1 - 0.003 17.2 0.0 5.9 6.4 0.0 3.1 3 0 0 3 3 3 1 FAD dependent oxidoreductase MRP-L51 PF10244.9 OAG44130.1 - 0.09 13.0 0.3 0.84 9.9 0.1 2.3 1 1 1 2 2 2 0 Mitochondrial ribosomal subunit S_locus_glycop PF00954.20 OAG44130.1 - 0.14 12.7 1.3 0.44 11.1 0.2 2.2 2 0 0 2 2 2 0 S-locus glycoprotein domain DUF3090 PF11290.8 OAG44131.1 - 0.03 14.1 0.0 0.036 13.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3090) DUF3712 PF12505.8 OAG44132.1 - 3.5e-09 37.0 1.6 2.8e-07 30.8 0.1 3.4 3 1 1 4 4 4 1 Protein of unknown function (DUF3712) LEA_2 PF03168.13 OAG44132.1 - 1.1e-07 32.3 1.0 0.011 16.2 0.0 4.3 5 0 0 5 5 5 2 Late embryogenesis abundant protein UNC-50 PF05216.13 OAG44132.1 - 0.12 12.0 0.0 5.7 6.4 0.0 2.1 2 0 0 2 2 2 0 UNC-50 family SR-25 PF10500.9 OAG44132.1 - 0.23 11.0 16.4 0.36 10.4 16.4 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Atrophin-1 PF03154.15 OAG44132.1 - 0.38 9.0 8.9 0.65 8.2 8.9 1.3 1 0 0 1 1 1 0 Atrophin-1 family S-methyl_trans PF02574.16 OAG44133.1 - 5.7e-61 206.7 0.0 6.5e-61 206.5 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase OTCace PF00185.24 OAG44134.1 - 2e-43 148.2 0.0 2.8e-43 147.7 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.21 OAG44134.1 - 5.2e-41 140.1 0.0 7.6e-41 139.6 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain DUF3984 PF13136.6 OAG44135.1 - 1.2e-32 113.6 19.2 6.9e-32 111.1 19.2 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF3984) S1-P1_nuclease PF02265.16 OAG44137.1 - 1e-63 215.5 0.0 1.2e-63 215.3 0.0 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease Nucleoporin_C PF03177.14 OAG44138.1 - 3.3e-112 376.2 0.0 4.3e-112 375.8 0.0 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.11 OAG44138.1 - 3.1e-52 177.8 0.0 4.2e-52 177.3 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like DRE2_N PF16803.5 OAG44139.1 - 4.5e-37 127.2 0.0 6.6e-37 126.7 0.0 1.2 1 0 0 1 1 1 1 Fe-S cluster assembly protein DRE2 N-terminus CIAPIN1 PF05093.13 OAG44139.1 - 1.4e-29 102.5 0.1 3.1e-29 101.4 0.1 1.5 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis ALAD PF00490.21 OAG44140.1 - 7.2e-121 403.2 0.0 8.8e-121 402.9 0.0 1.1 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase CFC PF09443.10 OAG44141.1 - 0.059 13.2 1.7 0.12 12.3 1.7 1.4 1 0 0 1 1 1 0 Cripto_Frl-1_Cryptic (CFC) GRAB PF10375.9 OAG44142.1 - 4.6e-09 35.8 0.1 8.6e-09 35.0 0.1 1.5 1 0 0 1 1 1 1 GRIP-related Arf-binding domain HALZ PF02183.18 OAG44142.1 - 0.041 14.1 0.7 0.041 14.1 0.7 5.4 3 2 4 7 7 7 0 Homeobox associated leucine zipper FAM184 PF15665.5 OAG44142.1 - 0.07 12.9 56.0 0.11 12.2 17.0 3.3 1 1 2 3 3 3 0 Family with sequence similarity 184, A and B DUF3584 PF12128.8 OAG44142.1 - 0.38 8.2 52.3 47 1.3 32.7 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) Tup_N PF08581.10 OAG44142.1 - 0.41 11.0 42.5 6.1 7.2 5.2 6.6 2 1 4 6 6 6 0 Tup N-terminal Spc7 PF08317.11 OAG44142.1 - 0.54 9.1 59.6 0.3 9.9 7.8 3.8 1 1 4 5 5 5 0 Spc7 kinetochore protein Filament PF00038.21 OAG44142.1 - 1.8 8.1 52.3 6.3 6.3 17.9 3.5 1 1 2 3 3 3 0 Intermediate filament protein CENP-F_leu_zip PF10473.9 OAG44142.1 - 2 8.4 62.6 0.039 14.0 21.4 3.5 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Golgin_A5 PF09787.9 OAG44142.1 - 2.4 7.5 56.0 2.5 7.5 23.2 3.3 1 1 2 3 3 3 0 Golgin subfamily A member 5 CtIP_N PF10482.9 OAG44142.1 - 2.5 8.2 39.8 1.9 8.5 15.2 4.0 2 2 2 4 4 4 0 Tumour-suppressor protein CtIP N-terminal domain GAS PF13851.6 OAG44142.1 - 3.9 6.8 52.6 2.2 7.6 21.4 3.2 1 1 3 4 4 4 0 Growth-arrest specific micro-tubule binding Cnn_1N PF07989.11 OAG44142.1 - 6.5 7.0 42.2 0.07 13.3 2.8 5.3 2 1 3 5 5 5 0 Centrosomin N-terminal motif 1 Baculo_PEP_C PF04513.12 OAG44142.1 - 8.2 6.5 23.3 2 8.5 1.7 4.1 2 2 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Atg14 PF10186.9 OAG44142.1 - 9.4 5.2 43.2 7.4 5.6 21.8 2.6 1 1 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 SHE3 PF17078.5 OAG44142.1 - 9.5 5.9 39.1 15 5.2 23.5 3.4 1 1 2 3 3 3 0 SWI5-dependent HO expression protein 3 Spindle_Spc25 PF08234.12 OAG44143.1 - 7.2e-09 35.7 0.0 1.9e-08 34.4 0.0 1.7 1 0 0 1 1 1 1 Chromosome segregation protein Spc25 Spc7 PF08317.11 OAG44143.1 - 0.0083 15.0 9.6 0.011 14.7 9.6 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein Vps54_N PF10475.9 OAG44143.1 - 0.015 14.6 1.1 0.058 12.7 1.1 1.8 1 1 0 1 1 1 0 Vacuolar-sorting protein 54, of GARP complex DUF724 PF05266.14 OAG44143.1 - 0.067 13.0 7.7 0.059 13.2 6.2 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF724) HAP1_N PF04849.13 OAG44143.1 - 0.083 12.1 9.8 0.12 11.6 9.8 1.2 1 0 0 1 1 1 0 HAP1 N-terminal conserved region Cob_adeno_trans PF01923.18 OAG44143.1 - 0.17 12.0 3.7 0.27 11.4 3.7 1.2 1 0 0 1 1 1 0 Cobalamin adenosyltransferase APG6_N PF17675.1 OAG44143.1 - 0.17 12.4 15.7 0.17 12.4 0.3 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF4407 PF14362.6 OAG44143.1 - 0.31 10.3 10.2 0.49 9.7 10.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ADIP PF11559.8 OAG44143.1 - 0.41 10.7 17.5 1 9.5 17.4 1.7 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF16 PF01519.16 OAG44143.1 - 0.8 10.2 4.6 1.4 9.4 4.6 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF16 SlyX PF04102.12 OAG44143.1 - 1.3 9.7 12.5 0.2 12.3 4.1 2.7 1 1 1 2 2 2 0 SlyX Cortex-I_coil PF09304.10 OAG44143.1 - 1.3 9.2 10.2 1.9 8.8 3.8 2.2 1 1 1 2 2 2 0 Cortexillin I, coiled coil RILP PF11461.8 OAG44143.1 - 1.5 9.1 4.9 4.9 7.5 4.9 2.0 1 1 0 1 1 1 0 Rab interacting lysosomal protein DUF4472 PF14739.6 OAG44143.1 - 1.9 9.2 11.8 0.2 12.4 2.7 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) Striatin PF08232.12 OAG44143.1 - 2.2 8.8 15.8 2.1 8.9 6.0 2.2 1 1 1 2 2 2 0 Striatin family Atg14 PF10186.9 OAG44143.1 - 2.5 7.1 9.8 3.3 6.7 9.8 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1664 PF07889.12 OAG44143.1 - 3.2 7.8 9.2 1.1 9.3 2.4 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) PRKG1_interact PF15898.5 OAG44143.1 - 4.1 8.4 13.0 1.7 9.6 6.4 2.2 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain FUSC PF04632.12 OAG44143.1 - 5.2 5.5 6.8 6.7 5.1 6.8 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family PKD_channel PF08016.12 OAG44144.1 - 0.25 10.0 10.1 0.24 10.0 1.6 2.3 1 1 1 2 2 2 0 Polycystin cation channel adh_short_C2 PF13561.6 OAG44145.1 - 4.6e-41 140.9 0.7 7e-40 137.0 0.1 2.1 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG44145.1 - 3e-36 124.7 0.8 6.1e-36 123.7 0.1 1.8 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 OAG44145.1 - 1.1e-08 35.3 0.1 3.9e-08 33.4 0.0 1.8 2 0 0 2 2 2 1 KR domain DUF2650 PF10853.8 OAG44145.1 - 0.1 12.3 8.4 0.29 10.9 8.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2650) SGTA_dimer PF16546.5 OAG44146.1 - 8.9e-27 92.7 1.4 1.8e-26 91.7 1.4 1.6 1 0 0 1 1 1 1 Homodimerisation domain of SGTA TPR_2 PF07719.17 OAG44146.1 - 3.6e-14 51.7 4.2 0.00011 22.0 0.1 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 OAG44146.1 - 1.3e-13 50.1 3.4 0.00024 20.8 0.1 3.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 OAG44146.1 - 1.1e-11 44.2 2.2 5.8e-08 32.3 0.3 3.4 1 1 2 3 3 3 3 TPR repeat TPR_8 PF13181.6 OAG44146.1 - 4.4e-09 35.8 4.4 0.17 12.2 0.1 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 OAG44146.1 - 6.4e-07 29.7 3.3 0.014 16.2 0.7 4.0 2 1 2 4 4 3 3 Tetratricopeptide repeat TPR_7 PF13176.6 OAG44146.1 - 1.7e-06 27.6 0.1 0.15 12.1 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 OAG44146.1 - 1.4e-05 25.6 6.8 0.04 14.6 4.3 2.9 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 OAG44146.1 - 2.8e-05 24.3 1.1 0.0025 18.1 0.4 2.6 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 OAG44146.1 - 3.5e-05 23.9 1.6 0.009 16.3 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 OAG44146.1 - 0.00031 20.8 0.1 0.02 15.0 0.1 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat STI1 PF17830.1 OAG44146.1 - 0.00054 19.8 2.8 0.00054 19.8 2.8 2.9 3 0 0 3 3 2 1 STI1 domain TPR_19 PF14559.6 OAG44146.1 - 0.0011 19.4 0.8 0.043 14.3 0.0 3.2 3 1 1 4 4 3 2 Tetratricopeptide repeat BTAD PF03704.17 OAG44146.1 - 0.0069 16.8 0.5 0.17 12.3 0.1 2.2 2 0 0 2 2 2 1 Bacterial transcriptional activator domain TPR_15 PF13429.6 OAG44146.1 - 0.013 14.7 0.6 0.026 13.7 0.6 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat XPC-binding PF09280.11 OAG44146.1 - 0.024 14.3 0.7 0.024 14.3 0.7 2.4 2 0 0 2 2 2 0 XPC-binding domain TPR_10 PF13374.6 OAG44146.1 - 0.041 13.8 2.7 0.083 12.8 0.4 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 OAG44146.1 - 0.055 14.1 4.5 2.4 9.0 0.2 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat RE_SinI PF09570.10 OAG44146.1 - 0.067 12.4 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 SinI restriction endonuclease MIT PF04212.18 OAG44146.1 - 0.11 12.5 0.8 1.1 9.4 0.3 2.6 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain Wzy_C_2 PF11846.8 OAG44146.1 - 0.25 11.3 1.0 0.37 10.7 1.0 1.2 1 0 0 1 1 1 0 Virulence factor membrane-bound polymerase, C-terminal DUF5339 PF17274.2 OAG44146.1 - 0.3 12.0 0.2 0.3 12.0 0.2 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF5339) Fasciclin PF02469.22 OAG44147.1 - 1.3e-15 57.7 0.0 1.9e-07 31.4 0.0 2.4 2 0 0 2 2 2 2 Fasciclin domain DUF3537 PF12056.8 OAG44147.1 - 0.088 11.6 0.2 0.67 8.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3537) VSP PF03302.13 OAG44147.1 - 1.2 7.9 4.1 0.36 9.6 1.1 1.6 2 0 0 2 2 2 0 Giardia variant-specific surface protein Herpes_capsid PF06112.11 OAG44147.1 - 9 6.3 8.1 25 4.9 8.1 1.7 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Peptidase_S28 PF05577.12 OAG44148.1 - 1.4e-34 119.6 0.0 2e-34 119.2 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S9 PF00326.21 OAG44148.1 - 0.0025 17.3 0.0 0.0064 16.0 0.0 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 OAG44148.1 - 0.13 11.5 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 PBP PF01161.20 OAG44150.1 - 1.6e-14 54.3 0.0 2.9e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Tmemb_cc2 PF10267.9 OAG44150.1 - 0.41 9.7 3.4 0.48 9.5 3.4 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Apt1 PF10351.9 OAG44150.1 - 3.3 6.4 12.5 4.3 6.1 12.5 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Menin PF05053.13 OAG44150.1 - 8.3 4.6 7.2 11 4.2 7.2 1.1 1 0 0 1 1 1 0 Menin GREB1 PF15782.5 OAG44150.1 - 8.7 3.3 12.6 11 3.0 12.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PAF-AH_p_II PF03403.13 OAG44152.1 - 8.9e-15 54.1 0.0 6.2e-07 28.3 0.0 2.1 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 OAG44152.1 - 8.6e-08 31.4 0.0 2.6e-07 29.8 0.0 1.7 1 1 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 OAG44152.1 - 0.00083 18.5 0.3 0.0057 15.7 0.3 2.0 1 1 0 1 1 1 1 Chlorophyllase Hydrolase_4 PF12146.8 OAG44152.1 - 0.001 18.4 0.0 0.034 13.4 0.0 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OAG44152.1 - 0.05 14.2 0.1 0.079 13.6 0.1 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 OAG44152.1 - 0.19 11.2 0.2 0.38 10.2 0.0 1.5 2 0 0 2 2 2 0 Prolyl oligopeptidase family Mit_ribos_Mrp51 PF11709.8 OAG44153.1 - 1.1e-89 301.6 0.8 4.3e-89 299.6 0.8 1.7 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit bZIP_Maf PF03131.17 OAG44153.1 - 0.11 13.1 1.3 0.14 12.7 0.2 1.7 2 0 0 2 2 2 0 bZIP Maf transcription factor Ribosomal_S17e PF00833.18 OAG44154.1 - 3.8e-60 201.2 0.4 4.5e-60 200.9 0.4 1.0 1 0 0 1 1 1 1 Ribosomal S17 Thioredoxin PF00085.20 OAG44155.1 - 4.6e-47 158.3 0.0 5.3e-25 87.4 0.0 4.3 3 1 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 OAG44155.1 - 3.4e-12 46.7 0.0 0.049 13.5 0.0 4.2 3 1 1 4 4 4 3 Thioredoxin-like domain HyaE PF07449.11 OAG44155.1 - 0.00013 21.9 0.0 1.1 9.2 0.0 3.9 4 0 0 4 4 4 1 Hydrogenase-1 expression protein HyaE Thioredoxin_2 PF13098.6 OAG44155.1 - 0.00059 20.3 1.0 2.4 8.7 0.1 3.7 3 2 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 OAG44155.1 - 0.0033 17.7 0.0 3.1 8.2 0.0 3.9 4 0 0 4 4 4 1 Thioredoxin-like Thioredoxin_3 PF13192.6 OAG44155.1 - 0.044 13.8 0.1 0.28 11.3 0.0 2.3 2 0 0 2 2 2 0 Thioredoxin domain Thioredoxin_7 PF13899.6 OAG44155.1 - 0.083 13.1 1.1 3 8.1 0.1 3.6 4 0 0 4 4 4 0 Thioredoxin-like Ost5 PF05251.12 OAG44155.1 - 0.19 12.0 1.0 0.66 10.3 0.0 2.2 2 0 0 2 2 2 0 Oligosaccharyltransferase subunit 5 E1_DerP2_DerF2 PF02221.15 OAG44156.1 - 1.5e-25 90.2 0.4 1.7e-25 90.0 0.4 1.1 1 0 0 1 1 1 1 ML domain Amidohydro_2 PF04909.14 OAG44157.1 - 8.8e-27 94.6 0.4 1e-26 94.4 0.4 1.0 1 0 0 1 1 1 1 Amidohydrolase Polysacc_deac_2 PF04748.13 OAG44157.1 - 0.21 10.8 0.0 0.27 10.4 0.0 1.3 1 0 0 1 1 1 0 Divergent polysaccharide deacetylase MFS_1 PF07690.16 OAG44158.1 - 1.6e-26 93.1 29.0 1.6e-26 93.1 29.0 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily BT1 PF03092.16 OAG44158.1 - 0.00015 20.1 1.4 0.00015 20.1 1.4 2.1 2 0 0 2 2 2 1 BT1 family Response_reg PF00072.24 OAG44159.1 - 5.4e-21 74.9 0.0 1.2e-20 73.8 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 OAG44159.1 - 2.4e-20 73.1 0.2 4.7e-20 72.2 0.2 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 OAG44159.1 - 1.5e-12 47.4 0.0 6.5e-12 45.3 0.0 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.6 OAG44159.1 - 0.0027 18.0 0.0 0.0073 16.6 0.0 1.8 1 0 0 1 1 1 1 GAF domain ETC_C1_NDUFA5 PF04716.14 OAG44160.1 - 3e-27 94.2 3.0 3.7e-25 87.5 0.8 2.4 2 0 0 2 2 2 2 ETC complex I subunit conserved region Ku_PK_bind PF08785.11 OAG44160.1 - 0.11 12.6 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 Ku C terminal domain like QCR10 PF09796.9 OAG44161.1 - 4.3e-29 100.3 0.2 5.9e-29 99.9 0.2 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Ank_3 PF13606.6 OAG44162.1 - 5.6e-13 47.8 0.0 0.00073 19.8 0.0 4.6 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.30 OAG44162.1 - 2.4e-12 46.7 1.3 0.0006 20.1 0.0 5.0 6 0 0 6 6 6 2 Ankyrin repeat Ank_4 PF13637.6 OAG44162.1 - 4.2e-12 46.3 0.1 0.016 15.8 0.0 4.2 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 OAG44162.1 - 9.4e-12 44.9 0.0 0.0042 17.4 0.0 4.4 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 OAG44162.1 - 1e-11 45.3 0.0 6e-08 33.2 0.0 3.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Acetyltransf_3 PF13302.7 OAG44163.1 - 1.7e-22 80.6 0.0 2.1e-22 80.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAG44163.1 - 5.8e-08 33.0 0.0 8e-08 32.5 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 OAG44163.1 - 9.9e-06 25.8 0.0 1.4e-05 25.3 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 OAG44163.1 - 0.00022 20.9 0.0 0.00063 19.4 0.0 1.7 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OAG44163.1 - 0.014 15.3 0.0 0.028 14.3 0.0 1.5 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OAG44163.1 - 0.049 14.1 0.0 0.083 13.3 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF4114 PF13448.6 OAG44163.1 - 0.1 13.4 0.0 0.21 12.4 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4114) ATP-synt_F PF01990.17 OAG44164.1 - 3.6e-34 117.0 0.1 4.1e-34 116.8 0.1 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit DUF2418 PF10332.9 OAG44165.1 - 2.5e-33 114.5 0.1 5.2e-33 113.4 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2418) DUF2105 PF09878.9 OAG44165.1 - 0.038 13.7 0.1 0.038 13.7 0.1 1.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2105) Pkinase_Tyr PF07714.17 OAG44167.1 - 4.4e-14 52.4 0.3 1.1e-12 47.8 0.3 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OAG44167.1 - 2.7e-13 49.9 0.0 8e-13 48.3 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.23 OAG44167.1 - 0.051 13.5 0.8 0.1 12.5 0.7 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family AMP-binding PF00501.28 OAG44168.1 - 8.2e-78 261.9 0.0 1e-77 261.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG44168.1 - 1.3e-14 55.0 0.2 2.3e-14 54.1 0.2 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain adh_short PF00106.25 OAG44169.1 - 4.9e-47 159.9 0.0 5.6e-47 159.7 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG44169.1 - 5.1e-42 144.0 0.0 5.9e-42 143.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG44169.1 - 1.4e-05 25.1 0.0 2.3e-05 24.4 0.0 1.4 1 1 0 1 1 1 1 KR domain Methyltransf_25 PF13649.6 OAG44169.1 - 0.014 16.1 0.0 0.029 15.1 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Epimerase PF01370.21 OAG44169.1 - 0.017 14.6 0.0 0.023 14.2 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 OAG44169.1 - 0.021 15.1 0.0 0.032 14.5 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain Methyltransf_11 PF08241.12 OAG44169.1 - 0.072 13.7 0.0 0.2 12.4 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Pyr_redox_2 PF07992.14 OAG44170.1 - 4.2e-09 36.0 0.0 8.6e-07 28.5 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 OAG44170.1 - 5.3e-06 25.1 0.0 0.00013 20.6 0.0 2.1 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Shikimate_DH PF01488.20 OAG44170.1 - 2.7e-05 24.3 0.0 0.0091 16.1 0.0 2.5 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase NAD_binding_8 PF13450.6 OAG44170.1 - 3e-05 24.2 0.1 0.00023 21.3 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 OAG44170.1 - 9.2e-05 21.7 0.0 0.0016 17.6 0.0 2.3 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 OAG44170.1 - 0.00017 21.6 0.0 0.035 14.1 0.0 2.6 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 OAG44170.1 - 0.0086 16.6 0.1 1.2 9.7 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG44170.1 - 0.0093 15.2 0.0 0.058 12.6 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.21 OAG44170.1 - 0.057 12.8 0.5 4.2 6.7 0.2 2.3 2 0 0 2 2 2 0 ThiF family NAD_binding_7 PF13241.6 OAG44170.1 - 0.14 12.7 0.1 0.92 10.0 0.0 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding Fungal_trans PF04082.18 OAG44171.1 - 1.2e-30 106.5 6.8 1.7e-30 105.9 6.8 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain MarR PF01047.22 OAG44171.1 - 0.18 11.8 0.0 0.48 10.4 0.0 1.7 1 0 0 1 1 1 0 MarR family Abhydrolase_3 PF07859.13 OAG44172.1 - 6.6e-53 179.7 0.0 8.7e-53 179.3 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 OAG44172.1 - 1.8e-12 46.8 0.0 2.2e-12 46.5 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 OAG44172.1 - 1e-06 28.4 0.0 1.4e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 OAG44172.1 - 0.067 12.4 0.1 13 5.0 0.0 2.4 2 1 0 3 3 3 0 Serine aminopeptidase, S33 COesterase PF00135.28 OAG44172.1 - 0.075 11.9 0.0 0.28 10.0 0.0 1.7 1 1 0 1 1 1 0 Carboxylesterase family Thioesterase PF00975.20 OAG44172.1 - 0.081 13.0 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain adh_short PF00106.25 OAG44173.1 - 2.7e-39 134.7 0.0 3.6e-39 134.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG44173.1 - 3.7e-29 101.9 0.0 5e-29 101.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG44173.1 - 3.6e-07 30.3 0.6 3.3e-05 23.9 0.1 2.4 2 1 0 2 2 2 1 KR domain 3Beta_HSD PF01073.19 OAG44173.1 - 7e-05 22.0 0.0 0.0001 21.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 OAG44173.1 - 0.00013 21.5 0.2 0.00019 21.0 0.2 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 OAG44173.1 - 0.0034 17.6 0.0 0.0065 16.7 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_10 PF13460.6 OAG44173.1 - 0.013 15.4 0.0 0.016 15.1 0.0 1.4 1 1 0 1 1 1 0 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 OAG44173.1 - 0.12 11.8 0.1 0.17 11.2 0.1 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase TRI12 PF06609.13 OAG44174.1 - 3.8e-48 164.3 20.2 5e-48 163.9 20.2 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG44174.1 - 2.8e-20 72.6 52.8 7.4e-20 71.2 48.3 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG44174.1 - 2.9e-14 52.8 6.5 2.9e-14 52.8 6.5 3.3 3 1 0 3 3 3 3 Sugar (and other) transporter DUF3522 PF12036.8 OAG44174.1 - 6.7 7.0 11.5 1.7 8.9 0.7 3.8 1 1 3 4 4 4 0 Protein of unknown function (DUF3522) DHO_dh PF01180.21 OAG44176.1 - 8.1e-69 232.1 0.1 3.7e-57 193.8 0.0 2.1 2 0 0 2 2 2 2 Dihydroorotate dehydrogenase FMN_dh PF01070.18 OAG44176.1 - 0.0013 17.8 0.0 0.095 11.7 0.0 2.7 3 0 0 3 3 3 2 FMN-dependent dehydrogenase DUF4574 PF15141.6 OAG44176.1 - 0.03 14.2 0.1 0.096 12.6 0.1 1.9 1 0 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 Acetyltransf_3 PF13302.7 OAG44177.1 - 1.2e-27 97.3 0.1 1.4e-27 97.1 0.1 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAG44177.1 - 0.021 15.0 0.0 0.025 14.8 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family NOG1_N PF17835.1 OAG44178.1 - 6.3e-49 166.0 0.9 1.7e-48 164.6 0.0 2.3 3 0 0 3 3 3 1 NOG1 N-terminal helical domain NOGCT PF08155.11 OAG44178.1 - 9.8e-28 95.9 2.5 1.9e-27 95.0 2.5 1.5 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.14 OAG44178.1 - 2e-25 88.3 0.2 4e-25 87.4 0.2 1.5 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.23 OAG44178.1 - 9.2e-16 57.9 0.0 2.2e-15 56.7 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OAG44178.1 - 6.9e-08 32.2 0.1 1.5e-07 31.0 0.1 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 OAG44178.1 - 0.0035 17.3 0.4 0.92 9.4 0.2 2.6 2 1 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 OAG44178.1 - 0.0042 16.5 1.5 0.011 15.1 0.1 2.0 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region Dynamin_N PF00350.23 OAG44178.1 - 0.0049 16.9 0.4 3.8 7.6 0.0 3.0 2 1 1 3 3 3 2 Dynamin family AAA_16 PF13191.6 OAG44178.1 - 0.057 13.8 0.3 0.45 10.9 0.0 2.6 2 1 1 3 3 3 0 AAA ATPase domain ADH_N PF08240.12 OAG44179.1 - 3.8e-07 30.0 0.0 8.7e-07 28.8 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG44179.1 - 5.9e-07 29.5 0.4 1.7e-06 28.1 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 OAG44179.1 - 0.0054 16.6 0.2 0.028 14.3 0.2 2.2 1 1 0 1 1 1 1 N-terminal domain of oxidoreductase RST PF12174.8 OAG44179.1 - 0.091 12.7 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 RCD1-SRO-TAF4 (RST) plant domain Zn_clus PF00172.18 OAG44181.1 - 2.7e-08 33.8 7.4 4.8e-08 33.0 7.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAG44181.1 - 7.3e-08 31.8 1.2 1.2e-07 31.0 1.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Got1 PF04178.12 OAG44183.1 - 2.6e-14 53.6 13.8 3.6e-14 53.2 13.8 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family AgrD PF05931.11 OAG44183.1 - 0.095 12.7 1.7 0.29 11.2 1.7 1.7 1 0 0 1 1 1 0 Staphylococcal AgrD protein CPP1-like PF11833.8 OAG44183.1 - 2.3 7.8 4.6 2.7 7.6 4.6 1.1 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Glyoxalase PF00903.25 OAG44184.1 - 1.7e-23 83.2 0.5 3.1e-16 59.7 0.0 2.7 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 OAG44184.1 - 9.6e-15 54.8 0.2 2.4e-06 27.7 0.0 2.6 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_5 PF14696.6 OAG44184.1 - 5e-05 23.5 0.3 0.001 19.3 0.3 2.7 1 1 0 1 1 1 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase_3 PF13468.6 OAG44184.1 - 0.0003 20.9 2.3 1.5 8.9 0.0 4.4 4 1 0 4 4 4 2 Glyoxalase-like domain Fungal_trans PF04082.18 OAG44184.1 - 0.0012 17.9 0.7 0.01 14.9 0.1 2.3 2 1 0 2 2 2 1 Fungal specific transcription factor domain Goodbye PF17109.5 OAG44184.1 - 1.4 9.4 3.5 11 6.5 0.0 3.5 4 0 0 4 4 4 0 fungal STAND N-terminal Goodbye domain TPR_17 PF13431.6 OAG44185.1 - 0.017 15.5 0.5 0.21 12.1 0.1 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 OAG44185.1 - 0.08 12.6 0.4 0.3 10.8 0.0 2.1 2 0 0 2 2 2 0 TPR repeat Snf7 PF03357.21 OAG44186.1 - 8.8e-11 41.7 9.8 1.4e-10 41.0 9.8 1.3 1 1 0 1 1 1 1 Snf7 Tam41_Mmp37 PF09139.11 OAG44186.1 - 0.29 10.5 1.9 0.49 9.8 1.9 1.3 1 0 0 1 1 1 0 Phosphatidate cytidylyltransferase, mitochondrial Amidase PF01425.21 OAG44187.1 - 4e-99 332.6 0.0 7.6e-98 328.4 0.0 2.1 1 1 0 1 1 1 1 Amidase Peptidase_S10 PF00450.22 OAG44189.1 - 1.2e-58 199.5 0.0 2.6e-58 198.4 0.0 1.4 1 1 0 1 1 1 1 Serine carboxypeptidase Peptidase_S9 PF00326.21 OAG44189.1 - 0.14 11.7 0.0 1 8.8 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family Aminotran_1_2 PF00155.21 OAG44190.1 - 3.2e-33 115.4 0.1 5.9e-24 84.9 0.0 3.3 3 0 0 3 3 3 3 Aminotransferase class I and II Beta_elim_lyase PF01212.21 OAG44190.1 - 0.0082 15.5 0.0 2.8 7.1 0.0 2.3 2 0 0 2 2 2 2 Beta-eliminating lyase Tachykinin PF02202.16 OAG44190.1 - 0.1 12.5 0.2 0.27 11.2 0.2 1.8 1 0 0 1 1 1 0 Tachykinin family DUF5519 PF17648.1 OAG44191.1 - 0.073 12.9 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5519) GAPES4 PF17157.4 OAG44191.1 - 0.17 12.3 0.1 0.4 11.1 0.1 1.7 1 1 0 1 1 1 0 Gammaproteobacterial periplasmic sensor domain Na_Ca_ex PF01699.24 OAG44192.1 - 5.2e-33 114.1 30.4 2.6e-17 63.2 9.0 2.5 2 1 0 2 2 2 2 Sodium/calcium exchanger protein DUF5418 PF17439.2 OAG44192.1 - 0.015 15.4 0.3 0.015 15.4 0.3 2.4 3 0 0 3 3 3 0 Family of unknown function (DUF5418) Phage_Coat_B PF05356.11 OAG44192.1 - 0.15 12.0 1.1 1 9.3 0.5 2.5 2 0 0 2 2 2 0 Phage Coat protein B Peptidase_S10 PF00450.22 OAG44193.1 - 1.5e-65 222.2 0.0 2e-65 221.9 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase A-2_8-polyST PF07388.11 OAG44193.1 - 0.18 10.3 0.2 0.25 9.9 0.2 1.1 1 0 0 1 1 1 0 Alpha-2,8-polysialyltransferase (POLYST) CoA_trans PF01144.23 OAG44194.1 - 2.9e-94 314.5 2.3 1.2e-59 201.4 0.3 2.1 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.6 OAG44194.1 - 2.2e-05 24.5 0.2 6.1e-05 23.0 0.0 1.7 2 0 0 2 2 2 1 Acetyl-CoA hydrolase/transferase C-terminal domain Mal_decarbox_Al PF16957.5 OAG44194.1 - 0.023 13.1 0.6 0.038 12.3 0.1 1.5 2 0 0 2 2 2 0 Malonate decarboxylase, alpha subunit, transporter TauD PF02668.16 OAG44195.1 - 2.9e-51 174.8 1.1 3.5e-51 174.6 1.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.16 OAG44196.1 - 1.2e-30 106.7 29.4 1.2e-30 106.7 29.4 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 OAG44196.1 - 0.0013 17.7 0.2 0.0049 15.8 0.0 2.2 2 1 0 2 2 2 1 MFS_1 like family Actin PF00022.19 OAG44197.1 - 2.4e-21 75.8 0.0 1.3e-18 66.8 0.0 2.5 3 0 0 3 3 3 2 Actin IBR PF01485.21 OAG44198.1 - 1.3e-09 38.1 28.5 5.8e-07 29.6 9.5 4.0 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain RRM_1 PF00076.22 OAG44198.1 - 1.7e-05 24.6 0.0 0.28 11.0 0.0 3.4 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RING_UBOX PF13445.6 OAG44198.1 - 0.00019 21.4 11.4 0.00019 21.4 11.4 3.7 3 1 0 3 3 3 1 RING-type zinc-finger DUF2996 PF11210.8 OAG44198.1 - 0.0012 19.3 0.0 0.005 17.3 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2996) zf-C3HC4 PF00097.25 OAG44198.1 - 0.0012 18.6 12.6 0.0012 18.6 12.6 3.8 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OAG44198.1 - 0.0023 17.7 9.0 0.0023 17.7 9.0 4.5 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OAG44198.1 - 0.0023 18.0 11.6 0.0023 18.0 11.6 4.1 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING DUF1816 PF08846.10 OAG44198.1 - 0.16 12.0 0.0 0.4 10.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1816) bZIP_1 PF00170.21 OAG44199.1 - 6.3e-07 29.4 14.0 1.1e-06 28.6 14.0 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 OAG44199.1 - 4.3e-06 26.7 16.0 8.8e-06 25.7 16.0 1.5 1 0 0 1 1 1 1 Basic region leucine zipper VIR_N PF15912.5 OAG44199.1 - 1.3 8.6 12.7 0.22 11.1 3.0 2.2 2 0 0 2 2 2 0 Virilizer, N-terminal NAM-associated PF14303.6 OAG44199.1 - 6.9 7.4 13.6 0.15 12.8 6.7 1.7 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain Arv1 PF04161.13 OAG44201.1 - 2.7e-65 220.5 0.1 3.5e-65 220.1 0.1 1.1 1 0 0 1 1 1 1 Arv1-like family MFS_1 PF07690.16 OAG44202.1 - 2.6e-35 122.0 49.9 4.2e-33 114.7 13.4 3.0 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.13 OAG44202.1 - 5.2e-15 54.9 14.3 9.7e-15 54.0 14.3 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 OAG44202.1 - 5.7e-12 45.2 3.8 5.7e-12 45.2 3.8 2.5 3 0 0 3 3 3 1 Sugar (and other) transporter Phage-MuB_C PF09077.11 OAG44202.1 - 0.0035 17.2 0.1 0.0035 17.2 0.1 2.5 2 0 0 2 2 2 1 Mu B transposition protein, C terminal OATP PF03137.20 OAG44202.1 - 0.049 11.9 3.3 0.068 11.5 0.8 2.2 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family NAT PF04768.13 OAG44203.1 - 8.5e-51 172.0 0.0 5.1e-50 169.4 0.0 2.0 2 0 0 2 2 2 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase NAD_binding_2 PF03446.15 OAG44204.1 - 2.7e-30 105.6 0.0 4.4e-30 104.9 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 OAG44204.1 - 7.9e-13 48.8 0.0 3e-12 47.0 0.0 1.9 1 1 1 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_11 PF14833.6 OAG44204.1 - 1e-09 38.7 0.0 2e-09 37.7 0.0 1.5 1 1 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Shikimate_DH PF01488.20 OAG44204.1 - 2.4e-09 37.4 0.0 6.1e-09 36.1 0.0 1.6 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 OAG44204.1 - 0.00097 19.4 0.1 0.0033 17.7 0.0 2.0 2 1 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 OAG44204.1 - 0.0031 17.7 0.0 0.0063 16.8 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain GFO_IDH_MocA PF01408.22 OAG44204.1 - 0.0069 17.2 0.0 0.026 15.3 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold IlvN PF07991.12 OAG44204.1 - 0.06 12.9 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain KR PF08659.10 OAG44204.1 - 0.14 12.1 0.1 0.62 9.9 0.0 2.0 2 1 0 2 2 2 0 KR domain FAD_binding_3 PF01494.19 OAG44205.1 - 1.9e-30 106.3 0.0 5.5e-30 104.8 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 OAG44205.1 - 5.5e-09 35.7 0.0 0.002 17.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OAG44205.1 - 3.2e-05 23.2 1.1 0.0043 16.2 0.2 2.5 2 1 0 2 2 2 2 Lycopene cyclase protein Pyr_redox PF00070.27 OAG44205.1 - 8.1e-05 23.1 0.1 0.69 10.5 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG44205.1 - 0.00023 21.3 0.0 0.00053 20.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SE PF08491.10 OAG44205.1 - 0.00023 20.3 0.0 0.00036 19.7 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase Pyr_redox_3 PF13738.6 OAG44205.1 - 0.0005 19.4 0.1 0.19 11.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAG44205.1 - 0.0029 16.8 0.2 0.0067 15.6 0.1 1.7 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAG44205.1 - 0.064 12.8 0.2 2.4 7.6 0.0 2.2 1 1 1 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.14 OAG44205.1 - 0.1 11.3 0.1 5.6 5.6 0.0 2.3 2 0 0 2 2 2 0 HI0933-like protein TPR_12 PF13424.6 OAG44206.1 - 6.9e-14 51.9 5.7 4.2e-08 33.4 0.1 4.4 4 1 1 5 5 5 2 Tetratricopeptide repeat Clr5 PF14420.6 OAG44206.1 - 2.9e-13 49.8 2.9 4.1e-12 46.1 0.1 3.7 4 0 0 4 4 4 1 Clr5 domain TPR_10 PF13374.6 OAG44206.1 - 9.7e-13 47.6 1.0 0.0037 17.1 0.3 5.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_MalT PF17874.1 OAG44206.1 - 0.0048 16.3 2.9 0.052 12.9 0.3 2.3 1 1 0 2 2 2 1 MalT-like TPR region TPR_19 PF14559.6 OAG44206.1 - 0.052 14.1 0.0 0.23 12.0 0.0 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat SPX PF03105.19 OAG44206.1 - 0.67 9.8 8.7 1.2 9.0 8.7 1.5 1 0 0 1 1 1 0 SPX domain TPR_7 PF13176.6 OAG44206.1 - 1.2 9.4 4.8 1.2 9.4 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Glyco_hydro_31 PF01055.26 OAG44208.1 - 2.8e-158 527.7 3.4 3.7e-158 527.3 3.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 OAG44208.1 - 6.9e-36 123.0 0.0 1.6e-35 121.8 0.0 1.6 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 OAG44208.1 - 2.6e-13 50.1 1.5 8.9e-13 48.4 1.5 2.0 1 0 0 1 1 1 1 Galactose mutarotase-like Amidase PF01425.21 OAG44209.1 - 7.7e-78 262.4 1.4 3e-77 260.5 1.4 1.8 1 1 0 1 1 1 1 Amidase Glyco_transf_28 PF03033.20 OAG44210.1 - 4.3e-18 65.7 0.2 1.6e-10 41.2 0.0 2.6 2 0 0 2 2 2 2 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 OAG44210.1 - 2.9e-05 23.1 0.0 5.6e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase ATG_C PF09333.11 OAG44210.1 - 0.00016 21.9 0.0 0.0006 20.1 0.0 2.0 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain Glyco_tran_28_C PF04101.16 OAG44210.1 - 0.064 13.2 0.4 0.3 11.0 0.0 2.3 2 0 0 2 2 2 0 Glycosyltransferase family 28 C-terminal domain UIM PF02809.20 OAG44210.1 - 1.8 8.7 34.3 0.21 11.6 2.3 5.3 6 0 0 6 6 6 0 Ubiquitin interaction motif adh_short_C2 PF13561.6 OAG44211.1 - 5.1e-35 121.1 0.2 5.1e-35 121.1 0.2 1.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG44211.1 - 2.6e-24 85.7 1.7 2e-23 82.9 1.7 2.1 1 1 0 1 1 1 1 short chain dehydrogenase Polysacc_deac_1 PF01522.21 OAG44211.1 - 7.4e-13 48.5 0.0 1.4e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 OAG44211.1 - 6.7e-05 22.6 0.0 0.00013 21.8 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) KR PF08659.10 OAG44211.1 - 0.098 12.6 0.6 0.71 9.8 0.3 2.2 1 1 1 2 2 2 0 KR domain DUF2194 PF09960.9 OAG44211.1 - 0.13 10.6 0.0 0.18 10.1 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2194) AA_permease_2 PF13520.6 OAG44212.1 - 7.4e-49 166.7 48.7 8.7e-49 166.5 48.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAG44212.1 - 8.8e-23 80.6 41.9 1.2e-22 80.2 41.9 1.1 1 0 0 1 1 1 1 Amino acid permease DUF962 PF06127.11 OAG44212.1 - 0.076 13.1 4.1 0.065 13.3 0.2 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF962) SID-1_RNA_chan PF13965.6 OAG44212.1 - 0.21 9.9 3.7 0.39 9.1 3.7 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Ribosomal_S7 PF00177.21 OAG44213.1 - 7.5e-36 123.0 2.0 9.4e-36 122.7 2.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e SDA1 PF05285.12 OAG44215.1 - 2.6e-95 319.8 41.1 2.6e-95 319.8 41.1 2.5 2 1 0 2 2 2 2 SDA1 NUC130_3NT PF08158.12 OAG44215.1 - 1.5e-23 82.9 0.0 4.3e-23 81.4 0.0 1.9 1 0 0 1 1 1 1 NUC130/3NT domain RNR_inhib PF08591.10 OAG44216.1 - 5.5e-12 46.9 0.6 2.1e-11 45.1 0.5 2.2 1 1 0 1 1 1 1 Ribonucleotide reductase inhibitor HET PF06985.11 OAG44217.1 - 1.3e-36 126.1 0.3 2.9e-36 125.0 0.3 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HAUS2 PF15003.6 OAG44218.1 - 0.69 9.6 9.3 1.9 8.1 4.3 2.7 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 2 GGACT PF06094.12 OAG44219.1 - 5.3e-07 30.3 0.3 1.2e-06 29.1 0.0 1.8 3 0 0 3 3 3 1 Gamma-glutamyl cyclotransferase, AIG2-like AIG2_2 PF13772.6 OAG44219.1 - 0.0025 18.1 0.0 0.053 13.9 0.0 2.4 2 0 0 2 2 2 1 AIG2-like family Transferase PF02458.15 OAG44220.1 - 3.3e-18 65.6 0.0 3.1e-15 55.8 0.0 2.5 2 1 0 2 2 2 2 Transferase family Pex14_N PF04695.13 OAG44220.1 - 0.023 15.4 0.4 0.036 14.7 0.4 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CAP_N PF01213.19 OAG44220.1 - 1.3 8.4 4.3 1.9 7.9 4.3 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal SesA PF17107.5 OAG44221.1 - 8.5e-05 22.7 3.4 0.00014 22.0 0.1 2.7 2 1 1 3 3 3 1 N-terminal domain on NACHT_NTPase and P-loop NTPases BST2 PF16716.5 OAG44221.1 - 0.2 12.2 3.0 0.31 11.7 1.2 2.3 1 1 0 1 1 1 0 Bone marrow stromal antigen 2 HIT PF01230.23 OAG44222.1 - 8.9e-20 71.3 0.0 1.3e-19 70.8 0.0 1.2 1 0 0 1 1 1 1 HIT domain CwfJ_C_1 PF04677.15 OAG44222.1 - 0.00065 19.6 0.0 0.00094 19.0 0.0 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 DcpS_C PF11969.8 OAG44222.1 - 0.001 19.5 0.1 0.0015 19.0 0.1 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HD_3 PF13023.6 OAG44223.1 - 9.6e-48 162.2 0.0 1.2e-47 161.9 0.0 1.1 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 OAG44223.1 - 2.1e-12 47.1 0.0 2.7e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 OAG44223.1 - 0.0046 17.2 0.0 0.0076 16.5 0.0 1.4 1 0 0 1 1 1 1 HD domain Cytochrom_B561 PF03188.16 OAG44224.1 - 5.4e-08 33.1 6.7 9.7e-08 32.2 6.7 1.4 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 XK-related PF09815.9 OAG44224.1 - 0.004 16.2 2.0 0.0069 15.5 0.4 2.0 2 1 0 2 2 2 1 XK-related protein DUF2306 PF10067.9 OAG44224.1 - 0.0062 16.7 2.8 0.0062 16.7 2.8 2.5 1 1 1 2 2 2 1 Predicted membrane protein (DUF2306) PepSY_TM PF03929.16 OAG44224.1 - 0.12 12.0 9.0 0.07 12.8 6.0 2.0 1 1 1 2 2 2 0 PepSY-associated TM region Phage_holin_2_4 PF16082.5 OAG44224.1 - 0.15 11.8 0.7 0.35 10.6 0.7 1.6 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like DUF4079 PF13301.6 OAG44224.1 - 4.4 7.5 14.5 1.6e+02 2.4 15.0 3.5 1 1 1 2 2 2 0 Protein of unknown function (DUF4079) HET PF06985.11 OAG44225.1 - 2.7e-32 112.1 0.1 4.7e-32 111.3 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HAUS6_N PF14661.6 OAG44226.1 - 1.5e-35 122.9 0.0 2.9e-35 121.9 0.0 1.5 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 6 N-terminus DUF4407 PF14362.6 OAG44226.1 - 1.3 8.3 3.7 3.8 6.8 3.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) FAD_binding_2 PF00890.24 OAG44228.1 - 3.9e-62 210.7 1.6 4.6e-62 210.5 1.6 1.0 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAG44228.1 - 3.1e-09 36.9 2.7 1.7e-08 34.5 1.8 2.4 1 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAG44228.1 - 4.9e-08 33.1 0.0 1.7e-07 31.4 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 OAG44228.1 - 4e-06 26.3 0.9 9.3e-06 25.1 0.4 1.8 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 OAG44228.1 - 6.5e-06 25.1 0.3 0.0079 14.9 0.2 2.4 2 0 0 2 2 2 2 HI0933-like protein Thi4 PF01946.17 OAG44228.1 - 7.5e-06 25.3 0.3 0.00038 19.8 0.2 2.6 3 0 0 3 3 3 1 Thi4 family FAD_oxidored PF12831.7 OAG44228.1 - 1.3e-05 24.7 0.7 4.1e-05 23.1 0.5 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG44228.1 - 0.00019 20.8 1.1 0.0013 18.1 1.2 2.1 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAG44228.1 - 0.00025 21.6 0.3 0.025 15.1 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OAG44228.1 - 0.00038 19.6 3.9 0.0073 15.4 0.0 2.7 3 0 0 3 3 3 1 Glucose inhibited division protein A Amino_oxidase PF01593.24 OAG44228.1 - 0.00092 18.6 1.2 0.012 14.9 0.1 2.6 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.21 OAG44228.1 - 0.064 12.5 0.1 0.14 11.4 0.1 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 OAG44228.1 - 0.11 11.7 0.0 1.6 7.9 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.16 OAG44232.1 - 4.4e-14 52.2 47.6 4e-12 45.7 47.4 2.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Cytomega_TRL10 PF06084.11 OAG44232.1 - 0.37 10.8 0.9 4.4 7.3 0.2 2.3 2 0 0 2 2 2 0 Cytomegalovirus TRL10 protein SET PF00856.28 OAG44233.1 - 2.7e-08 34.4 0.0 1.7e-07 31.8 0.0 2.4 2 2 0 2 2 2 1 SET domain zf-MYND PF01753.18 OAG44233.1 - 7.8e-07 29.1 9.4 7.8e-07 29.1 9.4 1.8 2 0 0 2 2 2 1 MYND finger HSM3_N PF18795.1 OAG44233.1 - 0.092 12.2 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 DNA mismatch repair protein HSM3, N terminal domain CpXC PF14353.6 OAG44233.1 - 0.25 11.4 2.1 0.45 10.6 0.0 2.5 3 0 0 3 3 3 0 CpXC protein Alpha-amylase PF00128.24 OAG44234.1 - 6e-38 131.3 0.0 1.3e-34 120.2 0.0 2.2 2 0 0 2 2 2 2 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 OAG44234.1 - 0.039 14.1 0.0 0.095 12.8 0.0 1.6 1 0 0 1 1 1 0 Maltogenic Amylase, C-terminal domain DUF3459 PF11941.8 OAG44234.1 - 0.04 14.3 0.0 0.097 13.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3459) hDGE_amylase PF14701.6 OAG44234.1 - 0.048 12.7 0.0 0.08 12.0 0.0 1.2 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain FAS_I_H PF18314.1 OAG44235.1 - 1.9e-80 269.3 0.2 4.4e-80 268.1 0.0 1.8 2 0 0 2 2 2 1 Fatty acid synthase type I helical domain Fas_alpha_ACP PF18325.1 OAG44235.1 - 8.7e-75 250.5 0.0 2.3e-74 249.1 0.0 1.8 1 0 0 1 1 1 1 Fatty acid synthase subunit alpha Acyl carrier domain ketoacyl-synt PF00109.26 OAG44235.1 - 3.6e-21 75.9 0.1 7.5e-21 74.8 0.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACPS PF01648.20 OAG44235.1 - 9.4e-18 64.4 0.0 2.6e-17 63.0 0.0 1.8 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.22 OAG44235.1 - 2.8e-11 43.5 0.0 7.6e-11 42.1 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.25 OAG44235.1 - 3.2e-05 23.5 0.0 0.00018 21.1 0.0 2.3 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 OAG44235.1 - 0.0022 18.0 0.0 0.0078 16.1 0.0 1.9 1 0 0 1 1 1 1 KR domain DUF1729 PF08354.10 OAG44236.1 - 3.1e-160 532.8 0.0 5.5e-160 532.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) Acyl_transf_1 PF00698.21 OAG44236.1 - 2.1e-91 306.8 0.0 1.9e-89 300.4 0.0 2.7 3 0 0 3 3 3 1 Acyl transferase domain FAS_meander PF17951.1 OAG44236.1 - 4.3e-55 185.5 0.0 1.2e-54 184.1 0.0 1.8 1 0 0 1 1 1 1 Fatty acid synthase meander beta sheet domain SAT PF16073.5 OAG44236.1 - 1.7e-39 136.0 0.0 4.8e-39 134.5 0.0 1.8 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis MaoC_dehydratas PF01575.19 OAG44236.1 - 1.2e-38 131.5 0.0 2.5e-38 130.4 0.0 1.6 1 0 0 1 1 1 1 MaoC like domain FAS_N PF17828.1 OAG44236.1 - 5.2e-38 130.0 0.0 1.4e-37 128.6 0.0 1.8 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta MaoC_dehydrat_N PF13452.6 OAG44236.1 - 1.7e-22 80.0 0.0 6e-22 78.2 0.0 2.0 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase NACHT PF05729.12 OAG44237.1 - 7.2e-09 35.8 0.3 1.8e-08 34.5 0.3 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 OAG44237.1 - 4.4e-05 23.9 0.1 0.00019 21.8 0.1 2.1 1 0 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.22 OAG44237.1 - 0.054 13.9 0.2 0.26 11.7 0.1 2.2 2 0 0 2 2 2 0 RNA helicase RsgA_GTPase PF03193.16 OAG44237.1 - 0.088 12.7 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase MMR_HSR1 PF01926.23 OAG44237.1 - 0.089 12.9 0.1 0.34 11.0 0.0 2.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase HET PF06985.11 OAG44238.1 - 1.1e-25 90.7 0.0 1.9e-25 89.9 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PRA1 PF03208.19 OAG44239.1 - 0.048 13.3 0.0 0.059 13.0 0.0 1.2 1 0 0 1 1 1 0 PRA1 family protein Fungal_trans_2 PF11951.8 OAG44240.1 - 8.6e-59 199.3 1.0 1.6e-58 198.4 1.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG44240.1 - 2.2e-11 43.7 4.9 3.8e-11 42.9 4.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_M1 PF01433.20 OAG44241.1 - 1.6e-77 260.0 0.2 2.3e-77 259.5 0.2 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 OAG44241.1 - 3.7e-57 194.3 0.1 7.2e-57 193.3 0.1 1.5 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 OAG44241.1 - 4e-40 138.0 0.0 5.4e-38 131.0 0.0 2.3 2 0 0 2 2 2 2 Peptidase M1 N-terminal domain Transp_cyt_pur PF02133.15 OAG44242.1 - 7.7e-104 347.9 35.2 8.9e-104 347.7 35.2 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin CcmD PF04995.14 OAG44242.1 - 3.6 7.7 5.7 2.2 8.4 0.7 2.9 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) DUF917 PF06032.12 OAG44243.1 - 3.1e-99 332.1 0.2 1e-98 330.4 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.18 OAG44243.1 - 1.1e-29 103.6 12.8 3.3e-25 88.9 0.7 3.7 3 1 1 4 4 4 3 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 OAG44243.1 - 4.3e-28 98.2 6.6 2.1e-26 92.7 0.0 3.3 4 0 0 4 4 4 2 Hydantoinase/oxoprolinase N-terminal region MutL PF13941.6 OAG44243.1 - 0.0054 15.4 0.6 0.11 11.1 0.0 2.3 2 0 0 2 2 2 1 MutL protein BcrAD_BadFG PF01869.20 OAG44243.1 - 0.0078 15.7 2.3 0.03 13.8 0.2 2.4 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family Amidohydro_1 PF01979.20 OAG44244.1 - 2.7e-21 76.3 1.7 3.9e-20 72.5 1.7 2.4 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 OAG44244.1 - 3.4e-11 43.3 3.7 8.6e-06 25.5 0.0 3.1 2 1 0 3 3 3 2 Amidohydrolase family AtuA PF07287.11 OAG44245.1 - 1.2e-120 402.5 0.0 1.4e-120 402.2 0.0 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA CoA_transf_3 PF02515.17 OAG44246.1 - 3.7e-44 151.3 0.0 2.4e-42 145.4 0.0 2.3 2 1 0 2 2 2 2 CoA-transferase family III DUF3891 PF13030.6 OAG44246.1 - 0.17 11.6 0.0 0.28 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3891) TRI12 PF06609.13 OAG44247.1 - 9.7e-16 57.3 21.6 2.8e-15 55.8 21.4 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG44247.1 - 5.2e-08 32.2 51.9 9e-06 24.8 45.5 3.1 2 1 0 2 2 2 1 Major Facilitator Superfamily FMO-like PF00743.19 OAG44249.1 - 2.6e-17 62.5 0.7 5.1e-14 51.6 0.0 2.4 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OAG44249.1 - 4.6e-11 42.8 0.0 1.5e-10 41.1 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 OAG44249.1 - 4.6e-09 35.9 0.0 6.7e-06 25.5 0.0 3.1 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 OAG44249.1 - 2.1e-07 30.5 0.0 1.6e-05 24.3 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAG44249.1 - 2.7e-06 26.8 0.0 0.007 15.6 0.0 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAG44249.1 - 2.4e-05 24.4 0.0 0.0027 17.7 0.0 3.0 3 0 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.17 OAG44249.1 - 0.21 10.8 0.0 0.78 8.9 0.0 1.9 2 0 0 2 2 2 0 Thi4 family AMP-binding PF00501.28 OAG44250.1 - 2.9e-87 293.0 0.2 3.7e-87 292.7 0.2 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG44250.1 - 9e-16 58.6 0.1 2.5e-15 57.2 0.1 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Flu_PB1 PF00602.17 OAG44250.1 - 0.053 11.6 0.1 0.093 10.8 0.1 1.3 1 0 0 1 1 1 0 Influenza RNA-dependent RNA polymerase subunit PB1 Solute_trans_a PF03619.16 OAG44251.1 - 1.1e-89 300.5 30.3 1.3e-89 300.3 30.3 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Brr6_like_C_C PF10104.9 OAG44251.1 - 1.9 8.3 11.8 0.77 9.5 1.4 3.2 3 1 0 3 3 3 0 Di-sulfide bridge nucleocytoplasmic transport domain ERGIC_N PF13850.6 OAG44251.1 - 4.5 7.7 7.2 2.1 8.7 0.2 3.2 3 1 0 3 3 3 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Goodbye PF17109.5 OAG44252.1 - 1.9e-13 50.9 0.0 7.1e-13 49.1 0.0 2.1 1 0 0 1 1 1 1 fungal STAND N-terminal Goodbye domain AAA_16 PF13191.6 OAG44252.1 - 1.9e-07 31.6 0.1 1.4e-06 28.8 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 OAG44252.1 - 3.2e-06 27.5 0.0 3.4e-05 24.2 0.0 2.7 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 OAG44252.1 - 0.00022 21.2 0.0 0.00081 19.3 0.0 2.0 1 1 0 1 1 1 1 NACHT domain AAA PF00004.29 OAG44252.1 - 0.069 13.6 0.0 0.19 12.1 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TPR_2 PF07719.17 OAG44252.1 - 0.19 11.9 5.6 6.2 7.2 0.1 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 OAG44252.1 - 0.26 11.2 4.3 1.2 9.1 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 OAG44252.1 - 0.31 11.3 3.8 3.2 8.2 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 OAG44252.1 - 2.7 8.2 5.2 9.1 6.6 0.1 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat Abhydrolase_1 PF00561.20 OAG44253.1 - 2.9e-52 177.8 0.0 7.4e-52 176.5 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG44253.1 - 0.00017 22.3 5.2 0.0004 21.1 5.2 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG44253.1 - 0.046 13.0 0.0 0.98 8.6 0.0 2.1 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Esterase PF00756.20 OAG44253.1 - 0.075 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Say1_Mug180 PF10340.9 OAG44253.1 - 0.24 10.2 0.0 0.33 9.7 0.0 1.1 1 0 0 1 1 1 0 Steryl acetyl hydrolase MFS_1 PF07690.16 OAG44254.1 - 6.2e-52 176.7 32.6 6.2e-52 176.7 32.6 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG44254.1 - 2e-13 50.1 2.0 2e-13 50.1 2.0 2.7 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 OAG44254.1 - 4e-08 32.2 0.7 4e-08 32.2 0.7 2.4 2 1 0 3 3 3 1 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 OAG44254.1 - 7.9e-08 32.0 1.9 7.9e-08 32.0 1.9 2.6 3 0 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB DUF2583 PF10762.9 OAG44254.1 - 0.09 13.2 1.6 0.33 11.4 1.6 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2583) OATP PF03137.20 OAG44254.1 - 1.5 7.0 14.8 0.035 12.4 5.5 2.6 3 1 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Sec23_trunk PF04811.15 OAG44255.1 - 5.1e-56 190.0 0.0 1e-55 189.0 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 OAG44255.1 - 4.1e-24 84.4 0.0 8.8e-24 83.3 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 OAG44255.1 - 2.3e-17 63.5 0.0 4.4e-17 62.6 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 OAG44255.1 - 3.7e-15 55.7 4.3 7.8e-15 54.6 4.3 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 OAG44255.1 - 2.7e-08 33.6 0.0 5.7e-08 32.5 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat DUF1678 PF07913.11 OAG44255.1 - 0.19 11.5 0.0 0.39 10.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1678) THOC2_N PF16134.5 OAG44256.1 - 1.9e-230 766.8 0.0 3.1e-230 766.1 0.0 1.3 1 0 0 1 1 1 1 THO complex subunit 2 N-terminus Tho2 PF11262.8 OAG44256.1 - 1.8e-98 329.4 0.0 3.5e-98 328.5 0.0 1.5 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.8 OAG44256.1 - 2.5e-25 88.3 0.0 1.1e-24 86.3 0.0 2.2 2 0 0 2 2 2 1 Transcription- and export-related complex subunit SpoVT_C PF15714.5 OAG44256.1 - 0.001 19.1 0.3 0.0022 18.0 0.3 1.4 1 0 0 1 1 1 1 Stage V sporulation protein T C-terminal, transcription factor Semialdhyde_dh PF01118.24 OAG44257.1 - 1.1e-06 29.0 0.0 1.7e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 OAG44257.1 - 8.1e-05 22.6 0.0 0.00012 22.1 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 OAG44257.1 - 0.02 14.5 0.0 0.027 14.0 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family GDP_Man_Dehyd PF16363.5 OAG44257.1 - 0.065 12.6 0.1 0.12 11.8 0.0 1.5 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase GFA PF04828.14 OAG44258.1 - 1.6e-11 44.4 0.1 2.8e-11 43.6 0.1 1.4 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme APG6_N PF17675.1 OAG44258.1 - 8e-05 23.2 0.1 0.00014 22.3 0.1 1.4 1 0 0 1 1 1 1 Apg6 coiled-coil region Nnf1 PF03980.14 OAG44258.1 - 0.0026 18.1 0.5 0.02 15.2 0.0 2.2 1 1 1 2 2 2 1 Nnf1 KASH_CCD PF14662.6 OAG44258.1 - 0.003 17.4 1.4 0.0049 16.7 1.4 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH Tektin PF03148.14 OAG44258.1 - 0.01 14.6 0.5 0.015 14.0 0.5 1.1 1 0 0 1 1 1 0 Tektin family DUF2353 PF09789.9 OAG44258.1 - 0.012 15.0 0.3 0.018 14.4 0.3 1.2 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) JIP_LZII PF16471.5 OAG44258.1 - 0.016 15.3 1.6 0.032 14.4 1.6 1.5 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II HOOK PF05622.12 OAG44258.1 - 0.021 13.0 0.2 0.031 12.4 0.2 1.1 1 0 0 1 1 1 0 HOOK protein ADIP PF11559.8 OAG44258.1 - 0.053 13.6 3.6 0.092 12.8 3.6 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding ABC_tran_CTD PF16326.5 OAG44258.1 - 0.091 13.0 3.4 0.17 12.2 3.4 1.5 1 0 0 1 1 1 0 ABC transporter C-terminal domain TMF_TATA_bd PF12325.8 OAG44258.1 - 0.092 13.0 2.7 0.18 12.0 2.7 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Phage_lysozyme2 PF18013.1 OAG44258.1 - 0.093 12.7 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Phage tail lysozyme GAS PF13851.6 OAG44258.1 - 0.094 12.1 4.5 0.17 11.2 4.5 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DivIC PF04977.15 OAG44258.1 - 0.1 12.3 4.9 0.2 11.4 4.3 1.7 1 1 0 1 1 1 0 Septum formation initiator DUF4795 PF16043.5 OAG44258.1 - 0.11 12.1 1.2 0.25 10.9 1.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) DUF3450 PF11932.8 OAG44258.1 - 0.16 11.3 2.8 0.32 10.2 2.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) PRKG1_interact PF15898.5 OAG44258.1 - 0.16 12.9 1.7 0.43 11.5 1.7 1.7 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain DUF5082 PF16888.5 OAG44258.1 - 0.18 12.1 2.2 0.32 11.3 2.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) DUF2968 PF11180.8 OAG44258.1 - 0.2 11.3 4.4 0.34 10.5 4.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) FlgN PF05130.12 OAG44258.1 - 0.23 11.9 5.4 0.42 11.1 5.4 1.4 1 0 0 1 1 1 0 FlgN protein KfrA_N PF11740.8 OAG44258.1 - 0.31 11.7 4.7 0.15 12.8 1.1 2.0 1 1 1 2 2 2 0 Plasmid replication region DNA-binding N-term ZapB PF06005.12 OAG44258.1 - 0.37 11.3 5.7 1.1 9.7 5.2 2.0 1 1 0 1 1 1 0 Cell division protein ZapB SseC PF04888.12 OAG44258.1 - 0.58 9.7 2.5 0.92 9.0 2.5 1.2 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family bZIP_2 PF07716.15 OAG44258.1 - 5.6 7.1 5.5 59 3.9 4.7 2.4 1 1 1 2 2 2 0 Basic region leucine zipper Vps5 PF09325.10 OAG44259.1 - 3.5e-10 39.8 4.2 5.7e-10 39.2 4.2 1.2 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 OAG44259.1 - 5.1e-10 39.3 0.0 9e-10 38.5 0.0 1.4 1 0 0 1 1 1 1 PX domain GTP_EFTU PF00009.27 OAG44260.1 - 6.2e-39 133.6 0.0 1e-38 132.8 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 OAG44260.1 - 1.2e-24 86.2 0.1 2.8e-24 85.0 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 OAG44260.1 - 6.8e-17 61.3 0.0 1.6e-08 34.4 0.0 2.5 2 0 0 2 2 2 2 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 OAG44260.1 - 3.1e-06 27.5 0.0 1.6e-05 25.2 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 RF3_C PF16658.5 OAG44260.1 - 0.00041 20.2 0.0 0.001 18.9 0.0 1.6 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain ArfGap PF01412.18 OAG44261.1 - 1.4e-29 102.6 0.4 2.7e-29 101.6 0.4 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf SAP PF02037.27 OAG44262.1 - 1.9e-07 30.7 0.2 3e-07 30.0 0.2 1.3 1 0 0 1 1 1 1 SAP domain RSB_motif PF16294.5 OAG44262.1 - 2.3e-07 31.0 0.1 2.3e-07 31.0 0.1 4.2 3 1 0 3 3 3 1 RNSP1-SAP18 binding (RSB) motif RRM_1 PF00076.22 OAG44262.1 - 0.043 13.6 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Abhydrolase_1 PF00561.20 OAG44264.1 - 9.7e-10 38.5 0.0 2e-05 24.4 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG44264.1 - 2e-09 38.4 0.0 5e-09 37.1 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG44264.1 - 2.3e-05 23.8 0.0 0.013 14.8 0.1 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 ABC_tran PF00005.27 OAG44265.1 - 8e-54 181.9 0.1 7.8e-30 104.2 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 OAG44265.1 - 5.5e-52 177.1 26.3 9e-35 120.6 7.0 3.0 3 0 0 3 3 3 2 ABC transporter transmembrane region AAA_23 PF13476.6 OAG44265.1 - 7.5e-07 29.9 0.4 0.0016 19.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.19 OAG44265.1 - 1.1e-06 28.2 4.5 0.028 13.9 0.3 4.1 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 OAG44265.1 - 3.6e-06 27.0 0.4 0.081 12.7 0.1 3.3 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 OAG44265.1 - 4.5e-06 26.7 0.2 0.015 15.2 0.1 2.8 2 1 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OAG44265.1 - 2.4e-05 24.4 0.4 0.039 14.0 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.6 OAG44265.1 - 0.00011 22.5 0.5 5.1 7.4 0.0 3.6 3 0 0 3 3 3 1 AAA domain Zeta_toxin PF06414.12 OAG44265.1 - 0.00081 18.7 0.6 0.057 12.7 0.1 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_29 PF13555.6 OAG44265.1 - 0.0009 18.9 0.6 1.4 8.7 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 OAG44265.1 - 0.002 18.5 0.2 2.9 8.3 0.1 2.9 2 0 0 2 2 2 1 AAA ATPase domain DUF87 PF01935.17 OAG44265.1 - 0.0023 18.0 1.4 0.026 14.6 0.1 2.8 3 0 0 3 3 2 1 Helicase HerA, central domain IstB_IS21 PF01695.17 OAG44265.1 - 0.01 15.5 0.1 3.1 7.5 0.0 2.7 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_25 PF13481.6 OAG44265.1 - 0.013 15.1 1.5 2.6 7.6 0.1 3.1 3 0 0 3 3 3 0 AAA domain T2SSE PF00437.20 OAG44265.1 - 0.019 14.0 0.0 0.18 10.9 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA PF00004.29 OAG44265.1 - 0.022 15.2 0.6 4.1 7.8 0.0 3.5 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 OAG44265.1 - 0.067 12.7 0.3 4.7 6.7 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region cobW PF02492.19 OAG44265.1 - 0.11 12.1 1.6 0.42 10.2 0.2 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 OAG44265.1 - 0.12 12.0 0.3 4.9 6.8 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.6 OAG44265.1 - 0.15 12.3 0.0 4.2 7.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 OAG44265.1 - 0.15 11.7 0.0 2 8.1 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain Dynamin_N PF00350.23 OAG44265.1 - 0.21 11.6 1.0 9.7 6.2 0.0 2.5 2 0 0 2 2 2 0 Dynamin family DEAD PF00270.29 OAG44265.1 - 0.22 11.2 0.4 71 3.1 0.0 3.2 3 0 0 3 3 3 0 DEAD/DEAH box helicase AAA_18 PF13238.6 OAG44265.1 - 0.24 12.0 0.6 34 5.0 0.1 3.0 3 0 0 3 3 2 0 AAA domain AAA_30 PF13604.6 OAG44265.1 - 0.41 10.3 1.8 7.5 6.2 0.1 2.8 3 0 0 3 3 2 0 AAA domain TrwB_AAD_bind PF10412.9 OAG44265.1 - 0.41 9.5 3.2 1.6 7.5 0.2 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain UQ_con PF00179.26 OAG44266.1 - 2.7e-39 134.0 0.0 3.7e-39 133.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 OAG44266.1 - 0.02 15.2 0.0 0.041 14.2 0.0 1.7 1 0 0 1 1 1 0 RWD domain UFC1 PF08694.11 OAG44266.1 - 0.091 12.4 0.1 0.18 11.4 0.1 1.4 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 BUD22 PF09073.10 OAG44266.1 - 6.2 6.0 14.2 7.1 5.9 14.2 1.1 1 0 0 1 1 1 0 BUD22 Abhydrolase_1 PF00561.20 OAG44267.1 - 1.6e-16 60.7 0.1 5.1e-14 52.5 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG44267.1 - 4.3e-16 60.2 7.6 1.6e-14 55.0 7.6 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG44267.1 - 2.3e-10 40.1 0.0 2e-09 37.1 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Esterase PF00756.20 OAG44267.1 - 0.024 14.3 0.0 0.042 13.5 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Bac_rhamnosid6H PF17389.2 OAG44268.1 - 0.065 12.5 0.0 7.3 5.7 0.0 2.2 2 0 0 2 2 2 0 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain TAL_FSA PF00923.19 OAG44269.1 - 8.2e-97 324.0 0.0 9.3e-97 323.8 0.0 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase DHHC PF01529.20 OAG44270.1 - 8.8e-28 97.1 6.6 8.8e-28 97.1 6.6 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF4199 PF13858.6 OAG44270.1 - 0.081 13.3 6.7 0.5 10.7 6.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) FtsK_4TM PF13491.6 OAG44270.1 - 0.28 10.9 9.5 1.4 8.6 3.0 2.1 2 0 0 2 2 2 0 4TM region of DNA translocase FtsK/SpoIIIE Ribosomal_60s PF00428.19 OAG44271.1 - 2.7 8.7 4.8 11 6.7 4.8 2.0 1 0 0 1 1 1 0 60s Acidic ribosomal protein Glyco_hydro_17 PF00332.18 OAG44273.1 - 3.6e-10 40.0 4.3 3.5e-07 30.1 1.1 2.3 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 Spore_III_AF PF09581.10 OAG44273.1 - 0.11 12.5 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) Grp7_allergen PF16984.5 OAG44273.1 - 0.17 11.9 0.0 0.28 11.2 0.0 1.3 1 0 0 1 1 1 0 Group 7 allergen WD40 PF00400.32 OAG44275.1 - 2.5e-13 50.3 9.2 0.85 10.6 0.0 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG44275.1 - 0.0028 17.9 0.0 5.9 7.3 0.0 3.8 2 2 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain DDHD PF02862.17 OAG44275.1 - 0.058 13.6 0.3 0.14 12.3 0.3 1.6 1 0 0 1 1 1 0 DDHD domain PALB2_WD40 PF16756.5 OAG44275.1 - 0.13 11.2 0.0 1.9 7.3 0.0 2.0 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain AAA_12 PF13087.6 OAG44276.1 - 9.9e-39 133.0 0.0 3.2e-38 131.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 OAG44276.1 - 6.4e-22 78.6 0.0 2.4e-12 47.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 OAG44276.1 - 3.1e-10 40.1 0.2 6.8e-08 32.4 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.6 OAG44276.1 - 3.5e-08 33.9 0.1 6e-07 29.9 0.1 2.5 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 OAG44276.1 - 2.8e-06 27.3 0.0 0.042 13.6 0.0 3.4 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 OAG44276.1 - 2.9e-05 24.1 0.0 7.4e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_16 PF13191.6 OAG44276.1 - 0.0014 19.0 0.1 0.0047 17.3 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OAG44276.1 - 0.002 18.4 0.0 0.015 15.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain DEAD PF00270.29 OAG44276.1 - 0.0063 16.3 0.0 0.011 15.6 0.0 1.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase PhoH PF02562.16 OAG44276.1 - 0.0096 15.4 0.0 0.02 14.3 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein DUF2075 PF09848.9 OAG44276.1 - 0.022 14.0 0.0 0.14 11.4 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_5 PF07728.14 OAG44276.1 - 0.023 14.7 0.0 0.12 12.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA PF00004.29 OAG44276.1 - 0.064 13.7 0.0 0.26 11.7 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 OAG44276.1 - 0.13 12.4 0.0 0.95 9.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain adh_short PF00106.25 OAG44278.1 - 6.3e-23 81.2 0.4 8.9e-23 80.8 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG44278.1 - 1.4e-16 60.8 0.0 1.6e-16 60.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 OAG44278.1 - 0.00024 20.6 0.2 0.0018 17.7 0.2 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 OAG44278.1 - 0.00066 19.6 0.0 0.0011 19.0 0.0 1.4 1 0 0 1 1 1 1 KR domain MAF_flag10 PF01973.18 OAG44278.1 - 0.027 14.2 0.0 0.068 12.9 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function DUF115 Methyltransf_31 PF13847.6 OAG44278.1 - 0.037 13.8 0.0 0.049 13.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain SRR1 PF07985.12 OAG44279.1 - 1.7e-09 37.6 0.0 2.8e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 SRR1 CAF20 PF17052.5 OAG44279.1 - 0.029 14.5 0.5 0.058 13.6 0.2 1.6 2 0 0 2 2 2 0 Cap associated factor RRP7 PF12923.7 OAG44279.1 - 0.031 14.4 0.1 0.067 13.3 0.1 1.5 1 0 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain Isochorismatase PF00857.20 OAG44280.1 - 2.9e-41 141.6 0.0 3.3e-41 141.3 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family DUF4479 PF14794.6 OAG44280.1 - 0.00052 19.8 0.0 0.0014 18.4 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4479) LicD PF04991.13 OAG44281.1 - 3.5e-26 92.7 0.9 6.5e-18 65.7 0.7 2.1 1 1 1 2 2 2 2 LicD family Nop14 PF04147.12 OAG44282.1 - 0.064 11.5 6.5 0.081 11.1 6.5 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 OAG44282.1 - 0.081 11.2 4.6 0.11 10.8 4.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Lin-8 PF03353.15 OAG44282.1 - 0.76 9.3 5.2 1.2 8.7 5.2 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist RNA_pol_3_Rpc31 PF11705.8 OAG44282.1 - 6.2 7.0 14.6 12 6.1 14.6 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Glyco_transf_54 PF04666.13 OAG44283.1 - 5.1e-09 35.4 0.0 3.5e-07 29.4 0.0 2.8 2 1 0 2 2 2 1 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region Beach PF02138.18 OAG44284.1 - 4.2e-121 403.6 0.1 8.2e-121 402.6 0.1 1.5 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 OAG44284.1 - 6.7e-11 42.2 0.0 2.4e-10 40.4 0.0 2.0 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.6 OAG44284.1 - 3.9e-08 33.6 0.0 1.1e-07 32.2 0.0 1.7 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily eIF-5a PF01287.20 OAG44284.1 - 1.1e-06 28.6 0.6 3.1e-06 27.2 0.1 2.1 2 0 0 2 2 2 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold WD40 PF00400.32 OAG44284.1 - 2.2e-06 28.3 0.8 0.055 14.4 0.0 4.2 3 0 0 3 3 3 2 WD domain, G-beta repeat DUF4704 PF15787.5 OAG44284.1 - 0.0075 15.5 0.1 0.052 12.8 0.1 2.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4704) GST_N PF02798.20 OAG44285.1 - 5.7e-14 52.2 0.1 2.5e-13 50.1 0.0 2.1 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 OAG44285.1 - 1.4e-12 47.8 0.0 2.9e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OAG44285.1 - 9.4e-10 38.6 0.1 1.5e-09 37.9 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OAG44285.1 - 1.2e-09 38.2 0.1 1.9e-09 37.6 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 OAG44285.1 - 1.6e-09 37.9 0.0 4.8e-09 36.4 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAG44285.1 - 0.0036 17.3 0.0 0.0075 16.3 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Peptidase_S8 PF00082.22 OAG44287.1 - 6.2e-36 124.2 10.7 1.2e-35 123.3 10.7 1.4 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 OAG44287.1 - 6.4e-17 62.0 0.1 1.6e-16 60.8 0.1 1.7 1 0 0 1 1 1 1 Peptidase inhibitor I9 Sugar_tr PF00083.24 OAG44288.1 - 2e-77 261.0 18.7 2.5e-77 260.7 18.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG44288.1 - 9.8e-19 67.5 30.0 2.5e-13 49.7 3.3 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily AA_permease_2 PF13520.6 OAG44290.1 - 1.6e-61 208.5 46.2 1.9e-61 208.2 46.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAG44290.1 - 2e-22 79.5 38.4 2.6e-22 79.1 38.4 1.0 1 0 0 1 1 1 1 Amino acid permease Cu_amine_oxid PF01179.20 OAG44291.1 - 2.3e-164 547.2 0.0 2.8e-164 546.9 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 OAG44291.1 - 6.4e-06 26.5 0.0 1.6e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 OAG44291.1 - 0.00046 20.4 0.0 0.00095 19.4 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Glyco_hydro_30 PF02055.16 OAG44292.1 - 1e-10 41.1 0.2 1.4e-10 40.7 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_30C PF17189.4 OAG44292.1 - 1.2e-08 35.0 1.7 2.8e-08 33.9 1.7 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain Glyco_hydro_59 PF02057.15 OAG44292.1 - 3.9e-06 26.3 0.0 6.2e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 Glyco_hydr_30_2 PF14587.6 OAG44292.1 - 0.026 14.1 2.4 0.077 12.6 0.0 2.5 3 0 0 3 3 3 0 O-Glycosyl hydrolase family 30 p450 PF00067.22 OAG44293.1 - 6.7e-51 173.5 0.0 8.9e-51 173.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Soyouz_module PF14313.6 OAG44293.1 - 0.081 12.7 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 N-terminal region of Paramyxovirinae phosphoprotein (P) p450 PF00067.22 OAG44294.1 - 1.1e-66 225.4 0.0 1.8e-66 224.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_3 PF01494.19 OAG44294.1 - 8.5e-47 160.1 0.0 1.5e-46 159.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_binding_1 PF00667.20 OAG44294.1 - 3.5e-26 92.2 0.7 3.6e-25 88.8 0.1 2.6 2 1 0 2 2 2 1 FAD binding domain Flavodoxin_1 PF00258.25 OAG44294.1 - 2.4e-20 73.2 0.0 5e-20 72.2 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 OAG44294.1 - 6.1e-12 46.2 0.0 1.4e-11 45.0 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 OAG44294.1 - 1.7e-05 25.1 0.0 0.00024 21.4 0.0 2.4 2 0 0 2 2 2 1 Flavodoxin domain NAD_binding_8 PF13450.6 OAG44294.1 - 9.2e-05 22.6 0.5 0.00025 21.2 0.5 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAG44294.1 - 0.00027 20.6 1.6 0.39 10.3 0.0 2.4 1 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 OAG44294.1 - 0.00045 20.7 0.3 0.21 12.2 0.1 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAG44294.1 - 0.00054 19.3 0.5 0.044 13.0 0.2 2.2 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAG44294.1 - 0.00054 18.8 0.4 0.0019 17.0 0.2 1.9 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 OAG44294.1 - 0.00067 19.0 0.2 0.0015 17.8 0.2 1.6 1 0 0 1 1 1 1 Thi4 family DUF998 PF06197.13 OAG44294.1 - 0.0027 17.3 0.2 0.0052 16.4 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF998) Amino_oxidase PF01593.24 OAG44294.1 - 0.0074 15.6 0.4 0.074 12.3 0.0 2.5 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 OAG44294.1 - 0.013 14.9 2.0 1.4 8.2 0.0 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OAG44294.1 - 0.022 13.9 1.3 0.077 12.1 1.4 1.8 1 1 1 2 2 2 0 FAD binding domain Pyr_redox_3 PF13738.6 OAG44294.1 - 0.032 13.5 2.8 0.089 12.0 1.8 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase CHASE2 PF05226.11 OAG44294.1 - 0.037 13.7 0.0 0.14 11.9 0.0 1.8 2 0 0 2 2 2 0 CHASE2 domain Lycopene_cycl PF05834.12 OAG44294.1 - 0.048 12.7 0.3 0.1 11.6 0.3 1.5 1 1 0 1 1 1 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 OAG44294.1 - 0.071 13.1 1.7 11 6.0 0.1 3.6 4 0 0 4 4 3 0 FAD-NAD(P)-binding Ribosomal_L22 PF00237.19 OAG44295.1 - 3.5e-26 91.4 0.0 1.8e-25 89.1 0.0 2.1 2 0 0 2 2 2 1 Ribosomal protein L22p/L17e RRM_1 PF00076.22 OAG44296.1 - 2.9e-49 164.7 0.6 2.7e-15 55.9 0.0 5.0 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OAG44296.1 - 2.3e-33 113.9 0.2 1.2e-20 73.1 0.1 4.3 4 0 0 4 4 4 3 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 OAG44296.1 - 8.7e-08 32.1 0.1 0.0092 16.0 0.0 3.6 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 OAG44296.1 - 2.7e-06 27.0 0.0 0.43 10.2 0.0 4.4 3 1 2 5 5 5 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 OAG44296.1 - 0.00013 22.2 6.3 0.99 9.6 0.0 5.5 5 0 0 5 5 5 2 Cytosolic domain of 10TM putative phosphate transporter Limkain-b1 PF11608.8 OAG44296.1 - 0.00022 21.2 1.2 3.6 7.7 0.0 4.5 3 1 1 4 4 4 1 Limkain b1 RL PF17797.1 OAG44296.1 - 0.00038 20.3 0.3 0.0064 16.4 0.0 2.9 3 0 0 3 3 3 1 RL domain DUF3306 PF11748.8 OAG44296.1 - 0.13 13.1 6.5 0.74 10.7 6.5 2.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) Atg14 PF10186.9 OAG44296.1 - 0.32 10.1 3.8 0.69 8.9 3.8 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TPR_14 PF13428.6 OAG44296.1 - 1.5 9.9 11.0 1.6 9.8 0.2 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat MFS_MOT1 PF16983.5 OAG44297.1 - 2.2e-64 214.8 30.3 6.1e-35 120.0 7.8 2.6 3 0 0 3 3 3 2 Molybdate transporter of MFS superfamily Sulfate_transp PF00916.20 OAG44297.1 - 3.5e-05 22.7 2.7 3.5e-05 22.7 2.7 2.4 1 1 1 2 2 2 2 Sulfate permease family Trp_oprn_chp PF09534.10 OAG44297.1 - 0.17 11.7 3.7 1.1 9.0 0.0 3.0 3 1 0 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) adh_short PF00106.25 OAG44298.1 - 1.4e-28 99.7 0.0 1.8e-28 99.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG44298.1 - 9.9e-22 77.6 0.0 1.3e-21 77.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG44298.1 - 3.3e-09 36.9 0.0 4.3e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 OAG44298.1 - 0.039 13.8 0.0 0.05 13.5 0.0 1.2 1 0 0 1 1 1 0 NAD(P)H-binding TadZ_N PF16968.5 OAG44298.1 - 0.071 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Pilus assembly protein TadZ N-terminal Sacchrp_dh_NADP PF03435.18 OAG44298.1 - 0.15 12.3 0.0 0.22 11.8 0.0 1.4 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain PhyH PF05721.13 OAG44299.1 - 1.1e-55 189.1 0.0 1.4e-55 188.8 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 OAG44299.1 - 0.16 12.4 0.0 0.38 11.2 0.0 1.7 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase Zn_clus PF00172.18 OAG44300.1 - 9.6e-08 32.0 8.8 9.6e-08 32.0 8.8 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 OAG44300.1 - 1.9e-06 26.9 1.5 1.2e-05 24.3 0.1 2.3 3 0 0 3 3 3 1 Fungal specific transcription factor domain Abhydrolase_1 PF00561.20 OAG44301.1 - 1.5e-16 60.8 0.1 2.2e-16 60.3 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 OAG44301.1 - 1e-10 41.7 0.0 2.1e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_6 PF12697.7 OAG44301.1 - 0.028 15.0 0.3 0.056 14.0 0.3 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG44301.1 - 0.039 13.2 0.0 0.23 10.7 0.0 2.0 2 0 0 2 2 2 0 Serine aminopeptidase, S33 G6PD_bact PF10786.9 OAG44303.1 - 1.4 8.4 8.9 2 7.9 8.9 1.1 1 0 0 1 1 1 0 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) PBP1_TM PF14812.6 OAG44304.1 - 0.01 16.2 0.1 0.021 15.2 0.1 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Fungal_trans_2 PF11951.8 OAG44305.1 - 2.2e-06 26.7 0.2 4e-06 25.9 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG44305.1 - 3.6e-06 27.0 10.5 3.6e-06 27.0 10.5 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Orthopox_A47 PF06334.11 OAG44305.1 - 0.12 11.6 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Orthopoxvirus A47 protein TMEM234 PF10639.9 OAG44306.1 - 4e-36 123.6 0.7 4.8e-36 123.3 0.7 1.1 1 0 0 1 1 1 1 Putative transmembrane family 234 EamA PF00892.20 OAG44306.1 - 0.001 19.3 8.5 0.15 12.2 8.5 2.2 1 1 0 1 1 1 1 EamA-like transporter family DUF2985 PF11204.8 OAG44306.1 - 0.21 11.8 2.2 1.4 9.1 0.1 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2985) LSR PF05624.14 OAG44306.1 - 0.9 9.6 0.1 0.9 9.6 0.1 2.7 3 0 0 3 3 3 0 Lipolysis stimulated receptor (LSR) Chitin_synth_1 PF01644.17 OAG44307.1 - 8e-75 250.3 0.1 1.3e-74 249.7 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 OAG44307.1 - 4.3e-30 103.5 0.0 8.2e-30 102.6 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 OAG44307.1 - 6.5e-21 74.5 4.7 3.5e-18 65.5 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 OAG44307.1 - 2.1e-07 31.1 7.1 2.1e-07 31.1 7.1 2.8 2 1 0 2 2 2 1 Glycosyl transferase family group 2 LMWPc PF01451.21 OAG44308.1 - 3.6e-28 98.7 0.0 4.1e-28 98.5 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Motilin_ghrelin PF04644.12 OAG44308.1 - 0.028 14.2 1.0 0.043 13.6 1.0 1.2 1 0 0 1 1 1 0 Motilin/ghrelin GST_N_3 PF13417.6 OAG44309.1 - 7.4e-08 32.7 0.0 1.6e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OAG44309.1 - 0.015 15.6 0.0 0.047 14.0 0.0 1.9 2 1 0 2 2 2 0 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAG44309.1 - 0.082 12.9 0.0 0.21 11.7 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain NmrA PF05368.13 OAG44310.1 - 4.7e-39 134.3 0.0 5.6e-39 134.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG44310.1 - 1.7e-13 50.9 0.1 2.6e-13 50.3 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAG44310.1 - 9e-08 31.9 0.0 1.6e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 OAG44310.1 - 2e-05 24.8 0.0 4.2e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain GDP_Man_Dehyd PF16363.5 OAG44310.1 - 0.00012 21.7 0.0 0.00017 21.1 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase KR PF08659.10 OAG44310.1 - 0.00026 20.9 0.0 0.00042 20.3 0.0 1.2 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 OAG44310.1 - 0.00044 19.4 0.0 0.00064 18.8 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 OAG44310.1 - 0.012 15.0 0.0 0.018 14.5 0.0 1.2 1 0 0 1 1 1 0 short chain dehydrogenase RmlD_sub_bind PF04321.17 OAG44310.1 - 0.024 13.8 0.1 0.039 13.0 0.1 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Semialdhyde_dh PF01118.24 OAG44310.1 - 0.042 14.3 0.0 0.19 12.2 0.0 2.1 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain LPD24 PF18839.1 OAG44310.1 - 0.091 13.0 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 Large polyvalent protein associated domain 24 PALP PF00291.25 OAG44310.1 - 0.1 12.0 0.3 6 6.2 0.0 2.4 1 1 1 2 2 2 0 Pyridoxal-phosphate dependent enzyme NAD_binding_4 PF07993.12 OAG44310.1 - 0.12 11.6 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Male sterility protein DXP_reductoisom PF02670.16 OAG44310.1 - 0.12 13.0 0.0 0.23 12.2 0.0 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase CRAL_TRIO PF00650.20 OAG44312.1 - 1.9e-44 151.2 0.0 5.8e-44 149.6 0.0 1.7 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 OAG44312.1 - 1.8e-15 56.8 0.1 6.1e-15 55.1 0.1 2.0 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 OAG44312.1 - 3.9e-06 27.1 0.0 7.7e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Mito_fiss_reg PF05308.11 OAG44313.1 - 0.035 14.2 5.7 0.046 13.8 5.7 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator Herpes_DNAp_acc PF04929.12 OAG44313.1 - 0.26 10.2 9.9 0.29 10.1 9.9 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Med3 PF11593.8 OAG44313.1 - 0.48 9.6 13.4 0.56 9.3 13.4 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal CAP_N PF01213.19 OAG44313.1 - 6.2 6.2 13.8 3.4 7.1 12.3 1.4 1 1 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal HIT PF01230.23 OAG44314.1 - 2.2e-23 82.8 0.3 3.1e-23 82.3 0.3 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 OAG44314.1 - 1e-13 51.8 0.0 1.4e-13 51.4 0.0 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 OAG44314.1 - 0.0014 18.5 0.0 0.0022 17.8 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CSTF2_hinge PF14327.6 OAG44314.1 - 0.089 13.3 0.0 0.18 12.3 0.0 1.4 1 0 0 1 1 1 0 Hinge domain of cleavage stimulation factor subunit 2 CAP59_mtransfer PF11735.8 OAG44315.1 - 2.5e-66 223.8 0.0 3.4e-66 223.4 0.0 1.2 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Asp PF00026.23 OAG44316.1 - 2.2e-66 224.4 1.9 2.7e-66 224.2 1.9 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OAG44316.1 - 2.4e-09 37.7 4.4 6.7e-09 36.2 2.2 2.4 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 OAG44316.1 - 3.7e-06 27.5 0.5 0.24 12.0 0.2 3.2 2 1 0 2 2 2 2 Aspartyl protease Pap_E4 PF02711.14 OAG44316.1 - 0.076 14.0 0.0 0.2 12.6 0.0 1.6 1 0 0 1 1 1 0 E4 protein UTP15_C PF09384.10 OAG44317.1 - 7e-42 142.6 0.4 1.4e-41 141.6 0.4 1.5 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.32 OAG44317.1 - 6.6e-18 64.8 0.3 0.00033 21.4 0.0 4.6 4 0 0 4 4 4 3 WD domain, G-beta repeat GFO_IDH_MocA PF01408.22 OAG44317.1 - 1.1e-17 65.0 0.6 2.8e-17 63.6 0.6 1.7 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold ANAPC4_WD40 PF12894.7 OAG44317.1 - 1.6e-07 31.5 0.1 0.0029 17.9 0.0 4.2 2 2 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Sacchrp_dh_NADP PF03435.18 OAG44317.1 - 0.0021 18.3 0.9 0.58 10.4 0.0 2.5 2 0 0 2 2 2 2 Saccharopine dehydrogenase NADP binding domain NAD_binding_3 PF03447.16 OAG44317.1 - 0.038 14.6 0.1 0.087 13.5 0.1 1.6 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain GFO_IDH_MocA_C PF02894.17 OAG44317.1 - 0.14 12.1 0.0 0.49 10.4 0.0 1.9 2 0 0 2 2 2 0 Oxidoreductase family, C-terminal alpha/beta domain HEPN_AbiU2 PF18734.1 OAG44317.1 - 0.16 11.5 0.0 0.31 10.5 0.0 1.4 1 0 0 1 1 1 0 AbiU2 CAF-1_p150 PF11600.8 OAG44317.1 - 4 7.1 9.7 2 8.1 4.5 2.2 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal C2 PF00168.30 OAG44318.1 - 3e-17 62.8 0.0 5.3e-17 62.0 0.0 1.4 1 0 0 1 1 1 1 C2 domain KIND PF16474.5 OAG44320.1 - 1.1 9.1 3.7 0.29 11.0 0.4 1.6 2 0 0 2 2 2 0 Kinase non-catalytic C-lobe domain Peptidase_S8 PF00082.22 OAG44321.1 - 1.3e-22 80.5 0.6 2e-22 79.8 0.6 1.3 1 0 0 1 1 1 1 Subtilase family Glyoxalase PF00903.25 OAG44322.1 - 1.1e-11 45.0 0.0 1.5e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily p450 PF00067.22 OAG44324.1 - 4.2e-81 273.1 0.0 5e-81 272.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CotJA PF11007.8 OAG44324.1 - 0.08 12.8 0.5 0.56 10.1 0.3 2.3 2 0 0 2 2 2 0 Spore coat associated protein JA (CotJA) FAD_binding_3 PF01494.19 OAG44325.1 - 2.5e-54 184.9 0.0 3.4e-54 184.4 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Fungal_trans PF04082.18 OAG44326.1 - 8.1e-15 54.6 0.1 1.2e-14 54.0 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain p450 PF00067.22 OAG44327.1 - 2.7e-78 263.8 0.0 3.1e-78 263.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PAN_1 PF00024.26 OAG44328.1 - 0.024 14.6 1.8 0.093 12.7 1.8 2.0 1 0 0 1 1 1 0 PAN domain ADH_zinc_N PF00107.26 OAG44329.1 - 2.4e-21 76.1 3.2 4e-20 72.1 2.6 2.3 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG44329.1 - 3.7e-19 68.6 0.2 7.1e-19 67.7 0.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 OAG44329.1 - 0.00022 22.3 1.6 0.00048 21.2 1.6 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase bMG3 PF11974.8 OAG44329.1 - 0.28 11.2 2.0 0.24 11.4 0.4 1.8 2 0 0 2 2 2 0 Bacterial alpha-2-macroglobulin MG3 domain 2-Hacid_dh_C PF02826.19 OAG44330.1 - 1e-54 184.6 0.0 2.2e-53 180.2 0.0 2.4 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DAO PF01266.24 OAG44330.1 - 1.2e-34 120.5 0.0 5.8e-34 118.2 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase 2-Hacid_dh PF00389.30 OAG44330.1 - 3e-16 59.3 0.0 5.6e-16 58.4 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 OAG44330.1 - 1.7e-07 31.6 0.0 0.00037 20.7 0.0 3.0 3 0 0 3 3 3 2 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_8 PF13450.6 OAG44330.1 - 8.7e-06 25.9 0.3 2.3e-05 24.5 0.1 1.9 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 OAG44330.1 - 0.00039 19.8 0.0 0.33 10.2 0.0 2.3 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.6 OAG44330.1 - 0.0014 18.6 0.0 0.073 13.1 0.0 2.6 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 OAG44330.1 - 0.0017 17.7 0.0 0.064 12.5 0.0 3.0 4 0 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAG44330.1 - 0.0035 16.5 0.0 0.041 13.0 0.0 2.3 3 0 0 3 3 3 1 FAD binding domain Glu_dehyd_C PF16912.5 OAG44330.1 - 0.0059 16.1 0.0 0.022 14.3 0.0 1.8 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus Shikimate_DH PF01488.20 OAG44330.1 - 0.015 15.4 0.0 0.47 10.5 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 OAG44330.1 - 0.018 14.9 0.0 1.3 8.9 0.0 2.4 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.27 OAG44330.1 - 0.041 14.4 0.0 0.23 12.0 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 OAG44330.1 - 0.045 14.0 0.1 0.65 10.3 0.0 2.6 2 0 0 2 2 2 0 TrkA-N domain ApbA PF02558.16 OAG44330.1 - 0.067 12.8 0.1 3.1 7.4 0.0 2.4 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.6 OAG44330.1 - 0.19 10.9 0.0 0.42 9.8 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 OAG44330.1 - 0.26 10.9 0.2 0.9 9.1 0.1 2.0 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF4588 PF15251.6 OAG44331.1 - 8.6e-08 32.3 4.4 9.6e-07 28.8 4.9 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF4588) SNF2_N PF00176.23 OAG44332.1 - 3.9e-75 252.8 0.1 8e-75 251.7 0.1 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 OAG44332.1 - 8.1e-45 151.5 1.6 8.1e-45 151.5 1.6 2.9 3 0 0 3 3 3 1 SLIDE HAND PF09110.11 OAG44332.1 - 4.8e-37 127.1 1.8 4.8e-37 127.1 1.8 3.3 4 0 0 4 4 3 1 HAND Helicase_C PF00271.31 OAG44332.1 - 1e-17 64.4 1.1 3.2e-17 62.9 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG44332.1 - 4.1e-11 43.2 0.0 2.8e-10 40.5 0.0 2.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Myb_DNA-binding PF00249.31 OAG44332.1 - 0.00011 22.3 0.2 3.2 8.0 0.4 4.0 3 0 0 3 3 3 2 Myb-like DNA-binding domain HDA2-3 PF11496.8 OAG44332.1 - 0.00057 19.1 0.0 0.0023 17.2 0.0 2.1 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 SWI2_SNF2 PF18766.1 OAG44332.1 - 0.00069 19.3 0.3 0.0025 17.5 0.0 2.1 2 0 0 2 2 2 1 SWI2/SNF2 ATPase DEAD PF00270.29 OAG44332.1 - 0.00073 19.3 0.0 0.0031 17.3 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase DEAD_2 PF06733.15 OAG44332.1 - 0.026 14.1 0.1 0.062 12.9 0.1 1.5 1 0 0 1 1 1 0 DEAD_2 Occludin_ELL PF07303.13 OAG44332.1 - 0.27 12.0 4.5 1.3 9.8 4.5 2.2 1 0 0 1 1 1 0 Occludin homology domain DUF4267 PF14087.6 OAG44333.1 - 8.6e-06 25.8 4.6 6.1e-05 23.1 0.1 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4267) DUF4188 PF13826.6 OAG44334.1 - 9.8e-31 106.5 0.2 1.5e-30 106.0 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4188) ABM PF03992.16 OAG44334.1 - 0.00083 19.4 0.1 0.0014 18.7 0.1 1.3 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Dehydratase_hem PF13816.6 OAG44334.1 - 0.028 13.8 0.6 0.054 12.9 0.6 1.4 1 1 0 1 1 1 0 Haem-containing dehydratase Adap_comp_sub PF00928.21 OAG44335.1 - 1.1e-58 198.8 0.0 1.3e-58 198.4 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 OAG44335.1 - 0.00054 19.9 0.0 0.00076 19.4 0.0 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF3602 PF12223.8 OAG44336.1 - 7.4e-23 81.0 10.6 6.2e-19 68.4 0.4 2.7 2 1 1 3 3 3 2 Protein of unknown function (DUF3602) Actin PF00022.19 OAG44337.1 - 5e-126 420.6 0.0 2.3e-125 418.4 0.0 1.8 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 OAG44337.1 - 0.029 13.2 0.0 0.69 8.7 0.0 2.5 1 1 0 1 1 1 0 MreB/Mbl protein zf-U1 PF06220.12 OAG44338.1 - 2.8e-06 27.0 1.0 3.8e-06 26.6 1.0 1.2 1 0 0 1 1 1 1 U1 zinc finger SART-1 PF03343.13 OAG44339.1 - 0.00065 18.4 16.8 0.00083 18.0 16.8 1.1 1 0 0 1 1 1 1 SART-1 family GNAT_acetyltr_2 PF13718.6 OAG44339.1 - 0.12 11.7 2.5 0.19 11.1 2.5 1.3 1 0 0 1 1 1 0 GNAT acetyltransferase 2 CDC45 PF02724.14 OAG44339.1 - 0.13 10.6 13.0 0.17 10.1 13.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Raftlin PF15250.6 OAG44339.1 - 0.32 9.7 7.4 0.44 9.3 7.4 1.1 1 0 0 1 1 1 0 Raftlin Pex14_N PF04695.13 OAG44339.1 - 0.55 10.9 17.0 0.074 13.7 12.3 2.0 2 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Rrn6 PF10214.9 OAG44339.1 - 1.1 7.6 12.7 1.3 7.5 12.7 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DUF2828 PF11443.8 OAG44339.1 - 1.3 7.0 9.0 1.5 6.8 9.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Presenilin PF01080.17 OAG44339.1 - 2 7.1 9.0 2.1 7.0 9.0 1.3 1 0 0 1 1 1 0 Presenilin DDHD PF02862.17 OAG44339.1 - 2 8.5 6.3 2.6 8.1 6.3 1.3 1 0 0 1 1 1 0 DDHD domain Connexin PF00029.19 OAG44339.1 - 4.7 6.9 5.8 7.7 6.2 5.8 1.5 1 0 0 1 1 1 0 Connexin Sec62 PF03839.16 OAG44339.1 - 4.7 6.7 7.2 7.1 6.1 7.2 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 Macoilin PF09726.9 OAG44339.1 - 5 5.6 16.5 7.1 5.1 16.5 1.2 1 0 0 1 1 1 0 Macoilin family NPR3 PF03666.13 OAG44339.1 - 9.2 4.9 10.9 12 4.6 10.9 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Glyco_tran_28_C PF04101.16 OAG44340.1 - 1.2e-14 54.7 0.1 4.3e-14 52.8 0.1 1.7 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain MRP-S28 PF10213.9 OAG44341.1 - 9.5e-47 158.6 0.1 1.9e-46 157.6 0.1 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein zf-CCCH PF00642.24 OAG44342.1 - 0.091 12.7 0.5 0.17 11.8 0.5 1.3 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) SH3_1 PF00018.28 OAG44343.1 - 1.2e-15 56.8 0.0 1.9e-15 56.2 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 OAG44343.1 - 2.9e-13 49.5 0.0 5.4e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 OAG44343.1 - 8.9e-10 38.1 0.0 1.5e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SF3b10 PF07189.11 OAG44344.1 - 2.4e-26 91.6 0.0 3.2e-26 91.2 0.0 1.2 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) Iso_dh PF00180.20 OAG44345.1 - 1.6e-74 251.2 0.0 1.8e-74 251.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase MBF1 PF08523.10 OAG44346.1 - 2.9e-26 91.7 0.9 2.9e-26 91.7 0.9 1.8 2 0 0 2 2 2 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 OAG44346.1 - 5.3e-05 23.2 0.0 8.6e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 OAG44346.1 - 0.027 14.8 0.0 0.059 13.7 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Abhydrolase_1 PF00561.20 OAG44348.1 - 1.8e-16 60.5 0.1 3.2e-16 59.7 0.1 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAG44348.1 - 8.4e-14 51.4 0.0 1.5e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OAG44348.1 - 4.9e-11 43.6 7.6 5.8e-11 43.4 7.6 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 OAG44348.1 - 2e-07 30.7 0.1 1.5e-05 24.5 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family DLH PF01738.18 OAG44348.1 - 2.8e-06 27.0 0.0 0.00013 21.6 0.0 2.2 2 0 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 OAG44348.1 - 0.00064 19.6 0.1 0.0043 16.9 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold BAAT_C PF08840.11 OAG44348.1 - 0.0023 17.9 0.0 0.027 14.4 0.0 2.0 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal FSH1 PF03959.13 OAG44348.1 - 0.013 15.2 0.0 0.066 12.9 0.0 1.9 1 1 0 1 1 1 0 Serine hydrolase (FSH1) PGAP1 PF07819.13 OAG44348.1 - 0.036 13.8 0.0 0.068 12.9 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_2 PF02230.16 OAG44348.1 - 0.039 13.8 0.0 3.2 7.5 0.0 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Abhydrolase_4 PF08386.10 OAG44348.1 - 0.041 14.0 0.0 0.13 12.4 0.0 1.8 2 0 0 2 2 2 0 TAP-like protein Thioesterase PF00975.20 OAG44348.1 - 0.043 13.9 0.3 0.084 13.0 0.3 1.6 1 1 0 1 1 1 0 Thioesterase domain DUF1326 PF07040.11 OAG44348.1 - 0.087 12.8 0.1 0.25 11.4 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1326) F-box-like PF12937.7 OAG44349.1 - 0.00027 20.7 0.0 0.00085 19.2 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAG44349.1 - 0.03 14.2 1.6 0.056 13.4 0.4 2.0 2 1 0 2 2 2 0 F-box domain F-box-like PF12937.7 OAG44350.1 - 0.0022 17.8 0.3 0.011 15.6 0.0 2.3 2 1 0 2 2 2 1 F-box-like DUF4465 PF14717.6 OAG44351.1 - 0.12 12.8 0.1 0.67 10.3 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4465) Glyco_hydro_76 PF03663.14 OAG44353.1 - 1.1e-128 429.8 11.2 1.5e-128 429.4 11.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 His_Phos_1 PF00300.22 OAG44353.1 - 4.6e-10 39.5 0.9 9e-10 38.6 0.1 1.8 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) Glyco_hydro_88 PF07470.13 OAG44353.1 - 0.088 11.9 6.2 0.11 11.5 0.4 2.5 3 0 0 3 3 3 0 Glycosyl Hydrolase Family 88 Acyl-CoA_dh_1 PF00441.24 OAG44354.1 - 1e-24 87.4 0.8 1.7e-24 86.7 0.8 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Tfb5 PF06331.12 OAG44354.1 - 1.7e-17 63.1 1.0 2.6e-17 62.6 0.2 1.7 2 0 0 2 2 2 1 Transcription factor TFIIH complex subunit Tfb5 Acyl-CoA_dh_N PF02771.16 OAG44354.1 - 5.9e-14 52.7 0.0 2.4e-13 50.7 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 OAG44354.1 - 2.1e-05 24.6 0.0 6e-05 23.2 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 OAG44354.1 - 0.00071 19.9 0.2 0.0014 18.9 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain 2OG-FeII_Oxy_2 PF13532.6 OAG44355.1 - 8.1e-27 94.7 0.0 1.9e-26 93.5 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Isochorismatase PF00857.20 OAG44355.1 - 5.9e-22 78.7 0.0 1.3e-20 74.4 0.0 2.3 1 1 0 1 1 1 1 Isochorismatase family FHA PF00498.26 OAG44356.1 - 8e-11 42.1 0.0 1.4e-10 41.3 0.0 1.4 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 OAG44356.1 - 0.0076 16.5 0.0 0.018 15.3 0.0 1.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain TPR_1 PF00515.28 OAG44357.1 - 6.2e-44 146.1 35.7 3e-06 26.8 0.1 11.6 10 1 1 11 11 11 10 Tetratricopeptide repeat TPR_2 PF07719.17 OAG44357.1 - 1.1e-38 128.2 32.5 3.2e-05 23.7 0.1 11.8 10 1 1 11 11 11 9 Tetratricopeptide repeat TPR_11 PF13414.6 OAG44357.1 - 6.8e-24 83.3 26.8 5.1e-07 29.3 0.4 8.6 5 2 3 8 8 8 7 TPR repeat TPR_8 PF13181.6 OAG44357.1 - 6e-23 79.1 37.3 0.0038 17.3 0.1 12.0 12 0 0 12 12 12 6 Tetratricopeptide repeat TPR_16 PF13432.6 OAG44357.1 - 6e-21 74.8 15.9 0.00012 22.6 0.1 7.1 5 1 1 7 7 7 6 Tetratricopeptide repeat TPR_17 PF13431.6 OAG44357.1 - 3.5e-20 70.9 14.1 0.007 16.7 0.0 9.0 9 0 0 9 9 8 5 Tetratricopeptide repeat TPR_7 PF13176.6 OAG44357.1 - 1.8e-16 58.9 22.1 0.019 15.0 0.1 9.6 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_19 PF14559.6 OAG44357.1 - 2.3e-16 60.0 22.6 4.6e-05 23.9 1.0 7.7 4 3 4 8 8 8 5 Tetratricopeptide repeat TPR_12 PF13424.6 OAG44357.1 - 3.8e-16 59.1 31.9 0.0037 17.5 0.9 8.7 5 3 3 8 8 8 6 Tetratricopeptide repeat TPR_9 PF13371.6 OAG44357.1 - 1.4e-13 50.8 10.8 0.00094 19.3 0.1 6.4 3 1 3 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.6 OAG44357.1 - 5.3e-11 42.4 21.7 0.079 13.8 0.2 9.7 3 3 7 10 10 10 2 Tetratricopeptide repeat ANAPC3 PF12895.7 OAG44357.1 - 8.4e-10 38.7 17.3 0.02 15.1 0.5 5.6 3 1 2 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 SHNi-TPR PF10516.9 OAG44357.1 - 3e-05 23.4 11.0 3.1 7.3 0.0 6.8 7 0 0 7 7 7 2 SHNi-TPR TPR_MalT PF17874.1 OAG44357.1 - 3.5e-05 23.4 7.3 7.6e-05 22.2 2.6 2.4 1 1 0 2 2 2 1 MalT-like TPR region TPR_10 PF13374.6 OAG44357.1 - 0.00018 21.3 30.2 0.15 12.0 0.2 9.0 10 0 0 10 10 9 2 Tetratricopeptide repeat NARP1 PF12569.8 OAG44357.1 - 0.0008 18.4 19.5 0.0049 15.9 0.7 4.7 3 1 2 5 5 5 2 NMDA receptor-regulated protein 1 MAS20 PF02064.15 OAG44357.1 - 0.0019 18.3 8.5 0.13 12.3 1.6 4.4 4 1 0 4 4 4 1 MAS20 protein import receptor DUF3856 PF12968.7 OAG44357.1 - 0.0036 17.4 9.2 6.6 6.8 0.0 5.8 3 1 1 5 5 5 1 Domain of Unknown Function (DUF3856) Sel1 PF08238.12 OAG44357.1 - 0.016 15.9 8.3 0.87 10.4 0.0 4.8 5 0 0 5 5 3 0 Sel1 repeat HemY_N PF07219.13 OAG44357.1 - 0.051 13.8 12.4 2.9 8.1 0.0 5.5 4 1 2 6 6 6 0 HemY protein N-terminus TPR_6 PF13174.6 OAG44357.1 - 0.06 14.0 30.7 6 7.7 0.5 9.2 10 0 0 10 10 8 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 OAG44357.1 - 0.073 13.5 1.5 22 5.5 0.1 3.5 3 1 0 3 3 3 0 Alkyl sulfatase dimerisation U1snRNP70_N PF12220.8 OAG44357.1 - 0.081 13.6 1.0 0.73 10.5 0.1 2.7 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal TPR_20 PF14561.6 OAG44357.1 - 1.5 9.2 8.3 3.5 8.0 0.2 4.4 5 0 0 5 5 3 0 Tetratricopeptide repeat MIT PF04212.18 OAG44357.1 - 2 8.5 21.7 26 5.0 0.2 6.9 6 0 0 6 6 6 0 MIT (microtubule interacting and transport) domain AP_endonuc_2 PF01261.24 OAG44358.1 - 1.2e-30 106.6 0.1 1.6e-30 106.1 0.1 1.1 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Shikimate_dh_N PF08501.11 OAG44359.1 - 3.6e-11 43.2 0.0 8.3e-11 42.0 0.0 1.7 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.20 OAG44359.1 - 2e-05 24.7 0.0 3.5e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 OAG44359.1 - 0.094 12.4 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA ThiF PF00899.21 OAG44359.1 - 0.13 11.6 0.5 0.23 10.8 0.5 1.3 1 0 0 1 1 1 0 ThiF family Aminotran_4 PF01063.19 OAG44360.1 - 4.2e-20 72.6 0.0 6.2e-19 68.7 0.0 2.1 2 0 0 2 2 2 1 Amino-transferase class IV tRNA-synt_1b PF00579.25 OAG44361.1 - 5.1e-23 81.8 0.0 9.1e-23 81.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) PRELI PF04707.14 OAG44362.1 - 2.7e-25 89.0 0.0 1.9e-21 76.5 0.0 2.2 2 0 0 2 2 2 2 PRELI-like family DUF3455 PF11937.8 OAG44363.1 - 3.4e-09 37.3 0.1 5.9e-08 33.3 0.1 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF3455) Sugar_tr PF00083.24 OAG44364.1 - 4.3e-92 309.4 11.5 8.7e-92 308.3 11.5 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter Pkinase PF00069.25 OAG44364.1 - 2.4e-73 246.8 0.0 3.4e-73 246.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG44364.1 - 3.7e-39 134.6 0.0 5.5e-39 134.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase MFS_1 PF07690.16 OAG44364.1 - 7.3e-30 104.1 36.6 7.2e-22 77.8 13.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily UBA_2 PF08587.11 OAG44364.1 - 7.6e-17 61.2 0.1 6.7e-16 58.1 0.1 2.3 2 0 0 2 2 2 1 Ubiquitin associated domain (UBA) AdenylateSensor PF16579.5 OAG44364.1 - 2.7e-16 60.1 0.1 3.2e-06 27.6 0.1 3.4 3 0 0 3 3 3 2 Adenylate sensor of SNF1-like protein kinase Kinase-like PF14531.6 OAG44364.1 - 1.5e-06 27.8 0.0 2.4e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like MFS_4 PF06779.14 OAG44364.1 - 2.6e-05 23.7 3.0 2.6e-05 23.7 3.0 2.2 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB RIO1 PF01163.22 OAG44364.1 - 0.0016 18.0 0.2 0.0029 17.2 0.2 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 OAG44364.1 - 0.011 15.1 0.1 0.022 14.1 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OAG44364.1 - 0.014 14.3 0.1 0.024 13.6 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain YukC PF10140.9 OAG44364.1 - 0.02 13.7 0.2 0.031 13.1 0.2 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC APH PF01636.23 OAG44364.1 - 0.13 12.2 0.2 0.83 9.5 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family 2OG-FeII_Oxy PF03171.20 OAG44365.1 - 5.1e-19 68.6 0.0 1.3e-18 67.3 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 OAG44365.1 - 2.5e-17 63.7 0.0 3.9e-17 63.1 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Glyoxalase_2 PF12681.7 OAG44365.1 - 0.17 11.8 0.0 0.34 10.8 0.0 1.4 1 0 0 1 1 1 0 Glyoxalase-like domain adh_short_C2 PF13561.6 OAG44366.1 - 2.7e-47 161.3 0.0 3.3e-47 161.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG44366.1 - 5.1e-41 140.3 0.0 6e-41 140.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG44366.1 - 2e-06 27.9 0.2 2.9e-05 24.1 0.1 2.4 1 1 1 2 2 2 1 KR domain Pyr_redox_3 PF13738.6 OAG44367.1 - 5.7e-13 48.8 0.0 1.2e-10 41.1 0.0 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAG44367.1 - 1.5e-10 40.8 0.0 1.2e-06 28.0 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 OAG44367.1 - 5.5e-10 38.3 0.0 6.4e-09 34.8 0.0 2.3 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OAG44367.1 - 1.6e-08 34.6 0.2 8.9e-08 32.3 0.1 2.4 1 1 1 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 OAG44367.1 - 7.8e-07 28.5 0.0 1.4e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 OAG44367.1 - 0.00018 20.8 0.3 0.0005 19.4 0.3 1.7 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAG44367.1 - 0.00023 20.9 3.1 0.002 17.8 1.0 2.9 1 1 0 3 3 3 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 OAG44367.1 - 0.00072 18.8 0.2 0.034 13.3 0.0 3.1 4 0 0 4 4 4 1 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 OAG44367.1 - 0.0026 16.5 0.4 0.0042 15.9 0.4 1.2 1 0 0 1 1 1 1 HI0933-like protein Shikimate_DH PF01488.20 OAG44367.1 - 0.0039 17.2 0.0 0.051 13.6 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.6 OAG44367.1 - 0.0069 16.4 0.2 0.068 13.2 0.1 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_oxidored PF12831.7 OAG44367.1 - 0.007 15.8 1.2 0.043 13.2 0.2 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 OAG44367.1 - 0.039 13.2 0.0 0.089 12.0 0.0 1.5 1 0 0 1 1 1 0 Thi4 family Amino_oxidase PF01593.24 OAG44367.1 - 0.089 12.1 0.0 0.4 9.9 0.0 2.0 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase 2-Hacid_dh_C PF02826.19 OAG44367.1 - 0.11 11.8 0.0 0.3 10.4 0.0 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GIDA PF01134.22 OAG44367.1 - 0.12 11.5 0.0 1.5 7.9 0.1 2.3 3 0 0 3 3 3 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 OAG44367.1 - 0.31 10.1 1.1 1.3 7.9 0.2 2.5 3 2 0 3 3 3 0 Lycopene cyclase protein Sugar_tr PF00083.24 OAG44368.1 - 2.6e-78 263.9 24.1 3e-78 263.7 24.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG44368.1 - 1.1e-29 103.5 60.4 9e-23 80.8 35.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2070 PF09843.9 OAG44368.1 - 0.26 9.5 11.3 0.43 8.8 11.3 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) TssO PF17561.2 OAG44368.1 - 9.4 6.3 5.8 29 4.7 0.6 2.3 2 0 0 2 2 2 0 Type VI secretion system, TssO Fungal_trans_2 PF11951.8 OAG44369.1 - 2.6e-05 23.2 0.1 0.0096 14.8 0.0 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain SmaI PF17411.2 OAG44369.1 - 0.1 11.7 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 Type II site-specific deoxyribonuclease SMC_N PF02463.19 OAG44370.1 - 1.6e-77 259.9 0.0 3.4e-77 258.8 0.0 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 OAG44370.1 - 7.8e-24 84.2 0.0 2.6e-23 82.6 0.0 2.0 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 OAG44370.1 - 1.5e-13 51.3 0.9 1.5e-05 25.0 0.3 4.0 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 OAG44370.1 - 0.0003 20.5 0.0 0.00061 19.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain HrpB7 PF09486.10 OAG44370.1 - 0.00071 20.0 14.8 0.00071 20.0 14.8 7.4 5 2 3 8 8 8 2 Bacterial type III secretion protein (HrpB7) DUF1664 PF07889.12 OAG44370.1 - 0.00092 19.2 65.4 0.024 14.6 4.4 7.6 5 2 2 7 7 7 5 Protein of unknown function (DUF1664) Osmo_CC PF08946.10 OAG44370.1 - 0.027 14.7 0.2 0.027 14.7 0.2 5.7 7 2 0 7 7 4 0 Osmosensory transporter coiled coil SbcCD_C PF13558.6 OAG44370.1 - 0.091 13.0 0.0 0.93 9.8 0.0 2.4 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit HTH_46 PF15977.5 OAG44370.1 - 0.14 12.2 0.1 1.9 8.6 0.0 2.7 2 0 0 2 2 2 0 Winged helix-turn-helix DNA binding EzrA PF06160.12 OAG44370.1 - 0.28 9.3 92.5 0.25 9.5 39.0 5.7 3 2 2 5 5 5 0 Septation ring formation regulator, EzrA ABC_tran PF00005.27 OAG44370.1 - 0.4 11.2 0.0 0.4 11.2 0.0 6.1 4 2 0 5 5 3 0 ABC transporter Pox_A_type_inc PF04508.12 OAG44370.1 - 3.4 7.7 8.6 28 4.8 1.2 5.1 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat GTP_EFTU PF00009.27 OAG44371.1 - 4.4e-49 166.7 0.0 1e-48 165.5 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 OAG44371.1 - 1.7e-42 143.9 5.3 2.7e-42 143.3 5.3 1.3 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 OAG44371.1 - 1.4e-21 76.3 0.0 2.8e-21 75.4 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 OAG44371.1 - 1.8e-05 25.0 0.0 4.2e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 OAG44371.1 - 3.6e-05 23.8 0.0 0.00011 22.3 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 OAG44371.1 - 0.00011 21.8 0.0 0.00039 20.0 0.0 1.9 2 0 0 2 2 2 1 Ras family EFG_II PF14492.6 OAG44371.1 - 0.0027 17.8 0.0 0.0084 16.2 0.0 1.9 1 1 0 1 1 1 1 Elongation Factor G, domain II SRPRB PF09439.10 OAG44371.1 - 0.0029 17.1 0.0 0.0061 16.0 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RF3_C PF16658.5 OAG44371.1 - 0.048 13.5 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain Roc PF08477.13 OAG44371.1 - 0.13 12.5 0.0 0.99 9.6 0.0 2.4 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Snurportin1 PF11538.8 OAG44371.1 - 0.44 10.8 1.6 1 9.6 1.6 1.6 1 0 0 1 1 1 0 Snurportin1 HORMA PF02301.18 OAG44372.1 - 1.6e-26 93.2 0.0 1.9e-26 93.0 0.0 1.0 1 0 0 1 1 1 1 HORMA domain DUF3530 PF12048.8 OAG44372.1 - 0.025 14.0 0.2 0.042 13.3 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) RNA_pol_Rpb1_5 PF04998.17 OAG44373.1 - 3.3e-74 249.7 0.0 7.6e-74 248.5 0.0 1.6 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 OAG44373.1 - 3.3e-74 248.6 0.1 7.8e-74 247.4 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_1 PF04997.12 OAG44373.1 - 1e-66 225.4 0.0 2e-66 224.5 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_3 PF04983.18 OAG44373.1 - 1.2e-36 126.0 0.0 3.1e-36 124.7 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 OAG44373.1 - 2e-25 88.8 0.0 6.3e-25 87.2 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 TAF8_C PF10406.9 OAG44374.1 - 9.6e-16 58.1 0.2 2.6e-15 56.7 0.2 1.7 1 0 0 1 1 1 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.13 OAG44374.1 - 0.019 14.9 0.0 0.037 14.0 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated Mitochondr_Som1 PF11093.8 OAG44375.1 - 2.1e-23 82.1 0.1 2.6e-23 81.8 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial export protein Som1 Rad51 PF08423.11 OAG44376.1 - 2e-10 40.3 0.0 2.5e-09 36.8 0.0 2.1 1 1 0 1 1 1 1 Rad51 PSY3 PF16836.5 OAG44376.1 - 0.016 14.8 0.0 0.04 13.4 0.0 1.7 1 1 0 1 1 1 0 Shu complex component Psy3, DNA-binding description FA_desaturase PF00487.24 OAG44377.1 - 3.9e-26 92.4 25.1 5.6e-26 91.9 25.1 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 OAG44377.1 - 8.9e-09 35.4 0.0 1.7e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF3425 PF11905.8 OAG44378.1 - 3.7e-17 62.5 0.6 7.5e-17 61.5 0.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Glyoxalase_3 PF13468.6 OAG44379.1 - 0.036 14.2 0.0 1 9.4 0.0 2.2 1 1 0 2 2 2 0 Glyoxalase-like domain ABM PF03992.16 OAG44380.1 - 2e-10 40.6 0.0 2.5e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase GST_N_3 PF13417.6 OAG44381.1 - 3.8e-15 56.1 0.0 1.6e-14 54.1 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 OAG44381.1 - 6.8e-15 55.2 0.0 1.3e-14 54.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OAG44381.1 - 2.1e-14 53.5 0.0 1.3e-12 47.8 0.0 2.9 3 1 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OAG44381.1 - 1.1e-11 44.8 0.0 1.8e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OAG44381.1 - 2.5e-09 37.2 0.0 4.6e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OAG44381.1 - 8.9e-07 28.8 0.1 1.6e-06 28.1 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 OAG44381.1 - 0.013 15.7 0.0 0.035 14.3 0.0 1.8 1 0 0 1 1 1 0 Glutaredoxin GST_C_6 PF17171.4 OAG44381.1 - 0.076 12.8 0.0 0.18 11.6 0.0 1.7 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Polyketide_cyc2 PF10604.9 OAG44382.1 - 3.6e-08 33.8 0.9 4.3e-08 33.5 0.9 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport AHSA1 PF08327.11 OAG44382.1 - 0.00057 20.1 4.8 0.0011 19.2 4.8 1.6 1 1 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Glyoxalase_4 PF13669.6 OAG44383.1 - 1.3e-10 41.5 0.0 0.00022 21.5 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 OAG44383.1 - 0.0047 17.1 0.0 0.33 11.1 0.0 2.7 2 1 0 2 2 2 1 Glyoxalase-like domain Glyoxalase PF00903.25 OAG44383.1 - 0.15 12.3 0.0 6.4 7.0 0.0 3.0 2 2 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily p450 PF00067.22 OAG44384.1 - 5.7e-67 226.5 0.0 7.3e-67 226.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4538 PF15061.6 OAG44384.1 - 0.037 13.7 0.8 0.087 12.6 0.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4538) ADH_zinc_N PF00107.26 OAG44385.1 - 7.6e-21 74.4 0.1 1.1e-20 74.0 0.1 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG44385.1 - 5.4e-20 71.3 0.2 1.2e-19 70.2 0.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Epimerase PF01370.21 OAG44385.1 - 0.013 15.0 0.1 0.017 14.6 0.1 1.1 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Fungal_trans PF04082.18 OAG44386.1 - 3.9e-21 75.3 0.4 9.8e-21 74.0 0.4 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Cyclase PF04199.13 OAG44387.1 - 9.1e-14 51.9 0.0 1.2e-13 51.4 0.0 1.3 1 0 0 1 1 1 1 Putative cyclase FMO-like PF00743.19 OAG44388.1 - 1.7e-13 49.9 1.4 8.1e-13 47.6 0.2 2.4 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OAG44388.1 - 2.4e-09 37.3 0.0 5.1e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAG44388.1 - 6.7e-05 22.3 0.0 0.00042 19.6 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAG44388.1 - 0.00054 20.0 0.0 0.004 17.2 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 OAG44388.1 - 0.0011 18.2 0.0 0.018 14.2 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 OAG44388.1 - 0.0063 15.8 0.1 0.076 12.3 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAG44388.1 - 0.054 12.7 0.1 0.65 9.2 0.0 2.5 3 0 0 3 3 3 0 Thi4 family DAZAP2 PF11029.8 OAG44389.1 - 0.035 15.0 1.9 0.21 12.5 1.1 2.2 2 0 0 2 2 2 0 DAZ associated protein 2 (DAZAP2) YabA PF06156.13 OAG44389.1 - 0.2 12.3 1.0 0.38 11.4 1.0 1.4 1 0 0 1 1 1 0 Initiation control protein YabA MAT1 PF06391.13 OAG44389.1 - 0.25 11.1 2.1 0.47 10.2 2.1 1.3 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 FbpA PF05833.11 OAG44389.1 - 3.7 6.2 6.8 5.7 5.6 6.8 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) AtuA PF07287.11 OAG44390.1 - 3.3e-115 384.6 0.0 4e-115 384.3 0.0 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA FMO-like PF00743.19 OAG44391.1 - 5.7e-19 67.9 0.3 3.8e-16 58.6 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 OAG44391.1 - 4.5e-17 62.2 0.0 8.1e-15 54.8 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG44391.1 - 2.1e-11 43.5 0.1 1.1e-09 37.9 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 OAG44391.1 - 2.7e-11 43.5 0.0 1.3e-09 38.2 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 OAG44391.1 - 4.6e-11 42.5 0.0 7.7e-10 38.5 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAG44391.1 - 1.2e-06 29.0 0.4 0.054 14.1 0.0 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAG44391.1 - 1.2e-05 25.3 0.4 1.8 8.5 0.0 4.2 4 0 0 4 4 4 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 OAG44391.1 - 0.0051 15.9 0.0 2.1 7.3 0.0 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 OAG44391.1 - 0.0063 15.8 0.3 0.035 13.4 0.1 2.0 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 OAG44391.1 - 0.02 14.5 0.0 11 5.4 0.0 3.3 4 0 0 4 4 4 0 FAD dependent oxidoreductase Thi4 PF01946.17 OAG44391.1 - 0.025 13.8 0.1 0.59 9.3 0.1 2.2 2 0 0 2 2 2 0 Thi4 family Shikimate_DH PF01488.20 OAG44391.1 - 0.068 13.2 0.6 0.47 10.5 0.0 2.4 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.14 OAG44391.1 - 0.088 11.5 0.6 0.31 9.7 0.1 2.1 3 0 0 3 3 3 0 HI0933-like protein p450 PF00067.22 OAG44392.1 - 6.7e-45 153.7 0.3 9.1e-45 153.2 0.3 1.1 1 0 0 1 1 1 1 Cytochrome P450 NmrA PF05368.13 OAG44392.1 - 1.1e-14 54.6 0.0 3.6e-14 52.9 0.0 1.8 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.6 OAG44392.1 - 7.5e-06 26.0 0.0 3.5e-05 23.8 0.0 2.0 2 0 0 2 2 2 1 NAD(P)H-binding Aldedh PF00171.22 OAG44393.1 - 6.9e-155 516.0 0.2 7.8e-155 515.9 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 OAG44393.1 - 5.4e-06 25.7 1.6 1.9e-05 23.9 1.6 1.7 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.11 OAG44393.1 - 0.0076 15.7 0.0 0.074 12.5 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1487) DUF917 PF06032.12 OAG44393.1 - 0.084 11.7 0.1 0.47 9.2 0.0 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF917) Aldo_ket_red PF00248.21 OAG44394.1 - 6.4e-64 216.0 0.0 7.6e-64 215.7 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Glyoxalase PF00903.25 OAG44395.1 - 6e-14 52.3 0.0 8.6e-14 51.8 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 OAG44395.1 - 2.5e-08 34.1 0.0 3.3e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 OAG44395.1 - 5.7e-08 33.5 0.0 1.9e-07 31.8 0.0 1.7 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_3 PF13468.6 OAG44395.1 - 0.00034 20.8 0.0 0.0028 17.8 0.0 1.9 1 1 0 1 1 1 1 Glyoxalase-like domain L51_S25_CI-B8 PF05047.16 OAG44395.1 - 0.13 12.2 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain MEDS PF14417.6 OAG44395.1 - 0.14 12.0 0.0 0.21 11.4 0.0 1.2 1 0 0 1 1 1 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain TRI12 PF06609.13 OAG44396.1 - 9.5e-50 169.6 18.4 1.3e-49 169.1 18.4 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) adh_short_C2 PF13561.6 OAG44396.1 - 2e-40 138.8 2.9 2.3e-21 76.5 0.0 2.7 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG44396.1 - 3.6e-31 108.2 6.5 1.4e-30 106.2 3.4 2.8 2 1 0 2 2 2 1 short chain dehydrogenase MFS_1 PF07690.16 OAG44396.1 - 3e-22 79.0 54.7 3.6e-22 78.8 50.3 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG44396.1 - 3.5e-08 32.7 5.4 3.5e-08 32.7 5.4 3.1 3 1 1 4 4 4 1 Sugar (and other) transporter KR PF08659.10 OAG44396.1 - 0.00052 20.0 0.3 0.0013 18.7 0.3 1.6 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG44396.1 - 0.09 12.2 0.1 0.16 11.4 0.1 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family HHH_5 PF14520.6 OAG44396.1 - 0.96 10.1 4.0 13 6.4 0.8 3.8 3 1 0 3 3 3 0 Helix-hairpin-helix domain CoA_binding_3 PF13727.6 OAG44396.1 - 8 6.4 7.1 0.59 10.1 0.7 2.5 3 0 0 3 3 3 0 CoA-binding domain TRI12 PF06609.13 OAG44397.1 - 3e-66 224.1 23.7 3.9e-66 223.7 23.7 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG44397.1 - 5.3e-20 71.6 48.1 5.3e-20 71.6 48.1 3.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG44397.1 - 2.5e-09 36.5 11.2 2.5e-09 36.5 11.2 3.2 3 0 0 3 3 3 2 Sugar (and other) transporter Nepo_coat PF03391.15 OAG44397.1 - 0.27 10.7 4.0 2.4 7.6 0.4 2.6 2 0 0 2 2 2 0 Nepovirus coat protein, central domain TRI12 PF06609.13 OAG44398.1 - 1.6e-34 119.3 22.3 3.6e-34 118.2 22.3 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG44398.1 - 4.2e-18 65.4 49.3 4.2e-18 65.4 49.3 3.0 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 OAG44399.1 - 1.1e-61 209.0 33.7 3.7e-39 134.6 18.5 2.0 1 1 1 2 2 2 2 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG44399.1 - 1.3e-22 80.2 46.3 1.3e-22 80.2 46.3 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG44399.1 - 1.8e-08 33.7 11.2 1.8e-08 33.7 11.2 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 OAG44400.1 - 2e-20 72.7 19.3 4.7e-11 41.8 10.3 2.1 1 1 1 2 2 2 2 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG44400.1 - 1e-14 54.3 38.5 1e-14 54.3 38.5 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily MIG-14_Wnt-bd PF06664.12 OAG44400.1 - 5.1e-05 22.6 5.8 5.1e-05 22.6 5.8 2.2 2 0 0 2 2 2 1 Wnt-binding factor required for Wnt secretion Acetyltransf_18 PF18014.1 OAG44400.1 - 0.027 14.3 0.7 12 5.7 0.0 3.1 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain p450 PF00067.22 OAG44401.1 - 2.7e-61 207.7 0.0 1.4e-60 205.4 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 adh_short_C2 PF13561.6 OAG44402.1 - 7.7e-29 100.9 0.0 9.5e-29 100.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG44402.1 - 2.7e-14 53.1 0.0 3.6e-14 52.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Fungal_trans PF04082.18 OAG44403.1 - 1.4e-28 99.7 0.7 1.8e-28 99.3 0.7 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain COesterase PF00135.28 OAG44405.1 - 3.3e-72 244.0 0.0 4.8e-72 243.5 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAG44405.1 - 0.008 16.1 0.1 0.029 14.2 0.0 2.0 3 0 0 3 3 3 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OAG44405.1 - 0.043 13.3 0.0 0.066 12.7 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 OAG44405.1 - 0.082 13.5 1.3 0.13 12.8 0.3 1.7 1 1 0 2 2 2 0 Alpha/beta hydrolase family Gpr1_Fun34_YaaH PF01184.19 OAG44406.1 - 8.6e-48 162.7 19.6 9.6e-48 162.5 19.6 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family zf-LITAF-like PF10601.9 OAG44406.1 - 2.5 8.5 5.9 19 5.6 6.0 2.3 1 1 0 1 1 1 0 LITAF-like zinc ribbon domain CBAH PF02275.18 OAG44407.1 - 3.2e-32 112.4 0.0 4.9e-31 108.6 0.0 1.9 1 1 0 1 1 1 1 Linear amide C-N hydrolases, choloylglycine hydrolase family AAT PF03417.16 OAG44407.1 - 0.045 13.4 0.0 0.067 12.9 0.0 1.4 1 0 0 1 1 1 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase ADH_N PF08240.12 OAG44408.1 - 5.1e-24 84.3 0.1 9.8e-24 83.3 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG44408.1 - 1.6e-18 67.0 0.1 2.4e-18 66.4 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAG44408.1 - 3.8e-06 28.0 0.0 5.8e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Aldedh PF00171.22 OAG44409.1 - 2.7e-124 415.2 0.0 3.5e-124 414.8 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Fungal_trans_2 PF11951.8 OAG44410.1 - 0.003 16.4 0.3 0.0067 15.3 0.1 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain PBP PF01161.20 OAG44411.1 - 3.2e-15 56.6 0.1 5e-15 56.0 0.1 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Herpes_capsid PF06112.11 OAG44411.1 - 0.035 14.2 11.4 0.049 13.7 11.4 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Vps62 PF06101.11 OAG44412.1 - 2.4e-51 174.7 0.0 3e-51 174.3 0.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 62 MFS_1 PF07690.16 OAG44413.1 - 1.7e-30 106.2 27.1 3.6e-30 105.1 27.5 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Methyltransf_12 PF08242.12 OAG44414.1 - 2.5e-06 28.2 0.0 6.4e-06 26.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG44414.1 - 0.00019 22.1 0.0 0.00063 20.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAG44414.1 - 0.0011 18.9 0.0 0.0016 18.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG44414.1 - 0.0012 19.4 0.0 0.0033 18.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG44414.1 - 0.028 14.2 0.0 0.068 13.0 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain CheR PF01739.18 OAG44414.1 - 0.074 12.5 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain p450 PF00067.22 OAG44415.1 - 1.1e-58 199.1 0.0 1.7e-58 198.5 0.0 1.2 1 1 0 1 1 1 1 Cytochrome P450 DLH PF01738.18 OAG44416.1 - 4e-19 69.0 0.1 4.9e-19 68.7 0.1 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 OAG44416.1 - 0.009 15.7 0.0 0.012 15.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Exog_C PF18026.1 OAG44416.1 - 0.036 14.1 0.0 0.072 13.2 0.0 1.4 1 0 0 1 1 1 0 Endo/exonuclease (EXOG) C-terminal domain DUF1275 PF06912.11 OAG44417.1 - 1.2e-47 162.3 14.7 1.5e-47 162.0 14.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) MFS_Mycoplasma PF07672.13 OAG44417.1 - 0.021 14.1 2.2 0.022 14.1 0.2 1.9 2 0 0 2 2 2 0 Mycoplasma MFS transporter DUF3188 PF11384.8 OAG44417.1 - 0.022 14.5 1.9 0.14 11.9 0.1 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3188) SLATT_3 PF18184.1 OAG44417.1 - 0.11 12.6 3.5 8.2 6.5 0.2 2.4 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 3 SLC3A2_N PF16028.5 OAG44417.1 - 0.26 10.9 1.2 0.55 9.8 0.4 1.9 2 0 0 2 2 2 0 Solute carrier family 3 member 2 N-terminus DUF1218 PF06749.12 OAG44417.1 - 0.98 10.0 8.0 0.22 12.1 1.9 2.8 3 1 0 3 3 3 0 Protein of unknown function (DUF1218) DUF1772 PF08592.11 OAG44417.1 - 5 7.4 16.1 4.4 7.6 4.8 2.6 1 1 0 2 2 2 0 Domain of unknown function (DUF1772) Peptidase_U4 PF03419.13 OAG44417.1 - 6 6.1 7.0 3.1 7.0 1.2 2.1 2 0 0 2 2 2 0 Sporulation factor SpoIIGA Cupin_1 PF00190.22 OAG44418.1 - 1.2e-41 141.8 0.0 1.2e-20 73.6 0.0 2.1 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 OAG44418.1 - 1.8e-24 85.3 1.2 1.9e-12 46.7 0.1 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 OAG44418.1 - 1.5e-09 37.4 0.0 0.00054 19.6 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.19 OAG44418.1 - 5.9e-08 32.7 0.3 0.00037 20.4 0.1 2.3 2 0 0 2 2 2 2 AraC-like ligand binding domain CENP-C_C PF11699.8 OAG44418.1 - 0.0055 16.9 0.0 3 8.1 0.0 2.9 3 0 0 3 3 3 1 Mif2/CENP-C like ARD PF03079.14 OAG44418.1 - 0.0089 16.2 0.3 2.9 8.0 0.0 2.3 2 0 0 2 2 2 2 ARD/ARD' family Cupin_6 PF12852.7 OAG44418.1 - 0.048 13.4 0.0 6.5 6.4 0.0 2.2 2 0 0 2 2 2 0 Cupin Fungal_trans PF04082.18 OAG44419.1 - 1.8e-14 53.4 0.1 1.2e-13 50.7 0.0 1.8 1 1 0 2 2 2 1 Fungal specific transcription factor domain Fungal_trans PF04082.18 OAG44420.1 - 1.3e-15 57.2 0.4 2.1e-15 56.5 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pox_mRNA-cap PF03341.13 OAG44420.1 - 0.025 13.9 0.1 0.041 13.2 0.1 1.2 1 0 0 1 1 1 0 Poxvirus mRNA capping enzyme, small subunit Sugar_tr PF00083.24 OAG44421.1 - 2.7e-124 415.5 19.0 7.1e-124 414.1 19.0 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG44421.1 - 4.8e-24 84.9 24.3 4.8e-24 84.9 24.3 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_5 PF05631.14 OAG44421.1 - 9.9e-05 21.4 0.8 9.9e-05 21.4 0.8 1.6 2 0 0 2 2 2 1 Sugar-tranasporters, 12 TM MASE4 PF17158.4 OAG44421.1 - 0.0055 16.0 0.7 0.046 13.0 0.0 2.3 2 0 0 2 2 2 1 Membrane-associated sensor, integral membrane domain ADH_zinc_N PF00107.26 OAG44422.1 - 2.8e-25 88.8 1.5 4.3e-25 88.2 0.6 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG44422.1 - 1.2e-19 70.2 1.0 2.3e-19 69.3 1.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 OAG44422.1 - 0.0001 23.4 0.0 0.00024 22.1 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 OAG44422.1 - 0.0061 15.9 1.8 0.0097 15.2 1.8 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ACP_syn_III PF08545.10 OAG44422.1 - 0.014 15.2 1.3 0.025 14.4 0.7 1.7 1 1 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III MCM2_N PF12619.8 OAG44423.1 - 0.46 10.8 8.0 1.5 9.1 7.2 2.2 1 1 1 2 2 2 0 Mini-chromosome maintenance protein 2 GCV_H PF01597.19 OAG44424.1 - 6.8e-42 142.2 1.8 8.2e-42 141.9 1.8 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein RnfC_N PF13375.6 OAG44424.1 - 0.067 13.2 0.1 0.12 12.3 0.1 1.4 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain Biotin_lipoyl PF00364.22 OAG44424.1 - 0.11 12.3 2.4 0.26 11.1 0.7 2.3 2 1 0 2 2 2 0 Biotin-requiring enzyme Spo12 PF05032.12 OAG44424.1 - 0.18 11.7 1.3 0.66 9.9 0.0 2.4 3 0 0 3 3 3 0 Spo12 family Ribosomal_S6 PF01250.17 OAG44425.1 - 2.2e-23 82.4 0.0 2.7e-23 82.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S6 Dynamin_N PF00350.23 OAG44426.1 - 6.1e-44 150.0 0.0 1.3e-43 148.9 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 OAG44426.1 - 3e-13 49.6 0.0 4.1e-11 42.6 0.0 2.3 2 0 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.23 OAG44426.1 - 1.8e-05 24.8 0.0 0.00016 21.7 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 OAG44426.1 - 0.045 14.1 0.0 0.23 11.8 0.0 2.3 1 0 0 1 1 1 0 AAA ATPase domain Roc PF08477.13 OAG44426.1 - 0.051 13.8 0.0 0.66 10.2 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_21 PF13304.6 OAG44426.1 - 0.052 13.4 0.0 0.098 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 OAG44426.1 - 0.053 13.2 0.0 0.22 11.2 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain GATase_4 PF13230.6 OAG44427.1 - 6.2e-15 54.8 0.0 5.2e-13 48.5 0.0 2.1 2 0 0 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.6 OAG44427.1 - 1.4e-08 35.0 0.0 3e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain PIG-Y PF15159.6 OAG44428.1 - 4.2e-23 82.1 8.6 6.2e-23 81.5 8.6 1.3 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y DUF1218 PF06749.12 OAG44428.1 - 0.17 12.5 1.9 7.6 7.1 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) OTOS PF15182.6 OAG44428.1 - 7 6.7 7.8 0.38 10.7 1.4 2.1 2 0 0 2 2 2 0 Otospiralin Abhydrolase_1 PF00561.20 OAG44429.1 - 8.8e-20 71.4 0.1 3.8e-17 62.8 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG44429.1 - 2e-18 67.8 0.0 2.6e-18 67.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG44429.1 - 6.7e-10 38.6 0.0 1.4e-09 37.6 0.0 1.5 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Ndr PF03096.14 OAG44429.1 - 0.0026 16.5 0.0 0.0042 15.8 0.0 1.3 1 0 0 1 1 1 1 Ndr family Abhydrolase_2 PF02230.16 OAG44429.1 - 0.025 14.4 0.0 7 6.4 0.0 2.4 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Chlorophyllase PF07224.11 OAG44429.1 - 0.14 11.1 0.0 0.21 10.5 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase DUF3530 PF12048.8 OAG44429.1 - 0.21 11.0 0.0 0.31 10.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) MOSC PF03473.17 OAG44430.1 - 1.1e-22 80.4 0.0 1.3e-21 77.0 0.0 2.6 3 0 0 3 3 3 1 MOSC domain Fer2 PF00111.27 OAG44430.1 - 1.9e-14 53.4 0.8 3.9e-14 52.4 0.8 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain 3-alpha PF03475.14 OAG44430.1 - 1.5e-10 40.8 0.0 2.5e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 3-alpha domain NAD_binding_1 PF00175.21 OAG44430.1 - 0.033 14.8 0.1 1.3 9.7 0.0 2.8 2 1 0 2 2 2 0 Oxidoreductase NAD-binding domain AA_permease_2 PF13520.6 OAG44431.1 - 5.8e-54 183.5 51.0 7.2e-54 183.2 51.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAG44431.1 - 3.7e-22 78.6 41.2 5.3e-22 78.0 41.2 1.1 1 0 0 1 1 1 1 Amino acid permease PalH PF08733.10 OAG44432.1 - 3.4e-110 368.1 0.2 4.5e-110 367.7 0.2 1.1 1 0 0 1 1 1 1 PalH/RIM21 EF-hand_9 PF14658.6 OAG44435.1 - 5.3e-05 23.5 0.1 0.0068 16.7 0.0 2.7 1 1 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 OAG44435.1 - 0.00042 20.7 0.2 0.024 15.1 0.0 2.8 3 1 0 3 3 3 1 EF-hand domain pair ORC6 PF05460.13 OAG44435.1 - 0.012 14.9 0.2 0.013 14.8 0.2 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Skp1 PF01466.19 OAG44435.1 - 0.51 10.5 3.5 0.3 11.2 0.5 2.1 2 0 0 2 2 2 0 Skp1 family, dimerisation domain PUL PF08324.11 OAG44436.1 - 6.2e-45 153.6 0.0 9e-45 153.0 0.0 1.2 1 0 0 1 1 1 1 PUL domain Peptidase_C97 PF05903.14 OAG44436.1 - 1.9e-38 131.6 0.0 3.5e-38 130.8 0.0 1.4 1 0 0 1 1 1 1 PPPDE putative peptidase domain Thioredoxin PF00085.20 OAG44436.1 - 1e-10 41.5 0.0 2.2e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 OAG44436.1 - 5.8e-05 23.5 0.0 0.00014 22.3 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like domain TraF PF13728.6 OAG44436.1 - 0.00026 20.9 0.0 0.0005 19.9 0.0 1.4 1 0 0 1 1 1 1 F plasmid transfer operon protein AhpC-TSA PF00578.21 OAG44436.1 - 0.012 15.5 0.0 0.022 14.7 0.0 1.4 1 0 0 1 1 1 0 AhpC/TSA family Cyclase PF04199.13 OAG44436.1 - 0.067 13.4 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 Putative cyclase GDA1_CD39 PF01150.17 OAG44437.1 - 8.3e-100 334.4 0.0 1.1e-99 333.9 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family IF3_C PF00707.22 OAG44438.1 - 7e-09 35.5 0.7 1.5e-08 34.5 0.7 1.6 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain mIF3 PF14877.6 OAG44438.1 - 1.6e-07 31.2 8.7 2.9e-06 27.1 8.7 2.1 1 1 0 1 1 1 1 Mitochondrial translation initiation factor Pep_M12B_propep PF01562.19 OAG44438.1 - 0.26 11.5 0.7 0.4 10.9 0.7 1.3 1 0 0 1 1 1 0 Reprolysin family propeptide Ribosomal_L27A PF00828.19 OAG44438.1 - 1.2 9.9 4.7 1.2 9.8 2.7 1.8 1 1 1 2 2 2 0 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A C2-set PF05790.15 OAG44438.1 - 1.3 9.3 4.0 4.5 7.5 0.1 2.6 2 1 0 2 2 2 0 Immunoglobulin C2-set domain Cation_efflux PF01545.21 OAG44439.1 - 5.5e-15 55.6 9.0 7.1e-15 55.3 9.0 1.1 1 0 0 1 1 1 1 Cation efflux family DUF2921 PF11145.8 OAG44440.1 - 0.1 10.4 0.2 0.15 9.9 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2921) Glyco_hydro_3_C PF01915.22 OAG44441.1 - 2.1e-45 155.2 0.0 4.2e-45 154.2 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 OAG44441.1 - 1.4e-34 119.9 0.0 3e-34 118.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 OAG44441.1 - 4.5e-23 81.1 0.1 8.4e-23 80.3 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Zn_clus PF00172.18 OAG44442.1 - 3.1e-07 30.4 11.4 5.5e-07 29.6 11.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HypF_C PF17788.1 OAG44442.1 - 0.088 13.5 0.0 0.39 11.4 0.0 2.1 1 0 0 1 1 1 0 HypF Kae1-like domain Atg14 PF10186.9 OAG44443.1 - 2.1e-14 53.3 4.5 1e-13 51.1 4.6 1.9 1 1 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 VPS38 PF17649.1 OAG44443.1 - 2.4e-09 36.6 0.8 0.0024 16.8 0.0 3.1 3 0 0 3 3 3 3 Vacuolar protein sorting 38 APG6 PF04111.12 OAG44443.1 - 0.00023 21.2 0.0 0.00043 20.3 0.0 1.5 1 0 0 1 1 1 1 Apg6 BARA domain PUMA PF15826.5 OAG44443.1 - 0.022 14.9 2.3 0.14 12.3 0.1 2.3 2 0 0 2 2 2 0 Bcl-2-binding component 3, p53 upregulated modulator of apoptosis DUF4407 PF14362.6 OAG44443.1 - 1 8.6 5.7 1.5 8.1 5.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CAP PF00188.26 OAG44444.1 - 4.5e-15 56.6 2.4 1.3e-14 55.1 2.4 1.8 1 0 0 1 1 1 1 Cysteine-rich secretory protein family SOG2 PF10428.9 OAG44444.1 - 1 8.5 26.4 1.4 8.0 26.4 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Apt1 PF10351.9 OAG44444.1 - 9.7 4.9 15.8 15 4.3 15.8 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain Snf7 PF03357.21 OAG44445.1 - 1.5e-36 125.6 16.3 2.6e-36 124.8 15.6 1.6 2 0 0 2 2 2 1 Snf7 YlqD PF11068.8 OAG44445.1 - 0.077 13.4 17.6 1.6 9.1 6.4 2.2 1 1 1 2 2 2 0 YlqD protein Peptidase_S46 PF10459.9 OAG44445.1 - 0.71 8.4 6.5 0.89 8.1 6.5 1.1 1 0 0 1 1 1 0 Peptidase S46 Remorin_C PF03763.13 OAG44445.1 - 0.71 9.8 8.1 1.5 8.7 7.9 1.7 1 1 0 1 1 1 0 Remorin, C-terminal region DUF3958 PF13125.6 OAG44445.1 - 5.3 7.3 12.7 0.2 11.9 4.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3958) Dynamin_N PF00350.23 OAG44446.1 - 8.9e-19 68.2 0.0 8.9e-19 68.2 0.0 2.6 3 0 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.23 OAG44446.1 - 3.4e-10 40.0 0.1 5e-09 36.2 0.0 3.0 2 2 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OAG44446.1 - 7.5e-07 28.9 4.0 8.2e-06 25.5 0.5 3.4 3 1 0 3 3 3 1 Elongation factor Tu GTP binding domain AAA_18 PF13238.6 OAG44446.1 - 0.0059 17.1 0.4 0.025 15.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain CobU PF02283.16 OAG44446.1 - 0.019 14.6 0.0 1.3 8.5 0.1 2.8 2 0 0 2 2 2 0 Cobinamide kinase / cobinamide phosphate guanyltransferase IIGP PF05049.13 OAG44446.1 - 0.023 13.8 0.0 0.058 12.5 0.0 1.6 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) TsaE PF02367.17 OAG44446.1 - 0.064 13.3 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Wzy_C PF04932.15 OAG44446.1 - 0.11 12.1 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 O-Antigen ligase Roc PF08477.13 OAG44446.1 - 0.12 12.6 0.3 2.8 8.2 0.0 3.1 2 1 1 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase FeoB_N PF02421.18 OAG44446.1 - 0.22 11.0 2.2 36 3.8 0.0 3.6 4 0 0 4 4 4 0 Ferrous iron transport protein B Vps5 PF09325.10 OAG44446.1 - 1.4 8.4 6.7 1.6 8.2 0.3 2.6 3 0 0 3 3 3 0 Vps5 C terminal like PP2C PF00481.21 OAG44447.1 - 4.1e-63 213.4 0.9 2.8e-52 177.9 0.9 3.4 1 1 2 3 3 3 2 Protein phosphatase 2C SUKH-3 PF14433.6 OAG44447.1 - 0.079 13.4 0.0 0.18 12.3 0.0 1.6 1 0 0 1 1 1 0 SUKH-3 immunity protein Pyr_redox_2 PF07992.14 OAG44448.1 - 8.3e-53 179.5 0.0 1.1e-52 179.1 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAG44448.1 - 1.5e-11 44.7 0.0 9e-10 39.0 0.0 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG44448.1 - 0.00047 19.5 0.7 0.36 10.0 0.1 2.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Ribosomal_L27A PF00828.19 OAG44449.1 - 9.4e-32 110.4 0.3 1.5e-31 109.7 0.3 1.3 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A p450 PF00067.22 OAG44450.1 - 6.3e-50 170.3 0.1 1.4e-49 169.1 0.1 1.5 2 0 0 2 2 2 1 Cytochrome P450 EcKinase PF02958.20 OAG44450.1 - 7.2e-21 74.8 0.0 5.9e-20 71.8 0.0 2.1 1 1 0 1 1 1 1 Ecdysteroid kinase APH PF01636.23 OAG44450.1 - 2.4e-15 57.1 0.0 5.4e-15 56.0 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 OAG44450.1 - 0.00016 20.6 0.0 0.00027 19.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) Glyco_transf_90 PF05686.12 OAG44451.1 - 2.2e-16 59.8 6.7 3.6e-06 26.1 0.0 4.2 3 2 1 4 4 4 4 Glycosyl transferase family 90 Spb1_C PF07780.12 OAG44452.1 - 2.2e-81 272.5 19.4 2.2e-81 272.5 19.4 3.0 3 0 0 3 3 3 1 Spb1 C-terminal domain FtsJ PF01728.19 OAG44452.1 - 3.3e-57 193.5 0.1 5.6e-57 192.7 0.1 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.8 OAG44452.1 - 2.3e-53 180.4 14.5 2.3e-53 180.4 14.5 4.4 5 0 0 5 5 5 1 Domain of unknown function (DUF3381) Ribosomal_L4 PF00573.22 OAG44453.1 - 4.8e-43 147.1 0.0 7.3e-43 146.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Fungal_trans PF04082.18 OAG44454.1 - 3.3e-40 137.8 0.1 4.3e-40 137.4 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG44454.1 - 1.9e-08 34.3 8.5 3.6e-08 33.4 8.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AHH PF14412.6 OAG44454.1 - 0.042 13.9 0.0 0.082 13.0 0.0 1.4 1 0 0 1 1 1 0 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH MARVEL PF01284.23 OAG44456.1 - 3.4e-07 30.4 6.7 5e-07 29.8 6.7 1.3 1 0 0 1 1 1 1 Membrane-associating domain DUF373 PF04123.13 OAG44456.1 - 0.38 10.1 3.2 0.42 10.0 2.0 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF373) CRCB PF02537.15 OAG44457.1 - 1.1e-34 118.6 12.3 1.3e-20 73.5 5.5 2.3 2 0 0 2 2 2 2 CrcB-like protein, Camphor Resistance (CrcB) Fungal_trans PF04082.18 OAG44458.1 - 2.9e-22 79.0 0.0 1.4e-20 73.4 0.0 2.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF997 PF06196.12 OAG44458.1 - 0.027 14.5 0.1 0.057 13.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF997) Enolase_C PF00113.22 OAG44459.1 - 3.9e-114 380.9 0.0 4.9e-114 380.5 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 OAG44459.1 - 2.9e-47 160.1 0.0 6.1e-47 159.1 0.0 1.6 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 OAG44459.1 - 7.3e-06 25.7 0.0 1.8e-05 24.4 0.0 1.7 2 0 0 2 2 2 1 Enolase C-terminal domain-like MAAL_C PF07476.11 OAG44459.1 - 0.11 11.6 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus Pyrophosphatase PF00719.19 OAG44460.1 - 1.2e-54 184.4 0.0 1.6e-54 184.1 0.0 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase HPP PF04982.13 OAG44462.1 - 8e-40 135.8 6.1 1.1e-39 135.3 6.1 1.2 1 0 0 1 1 1 1 HPP family PIRT PF15099.6 OAG44462.1 - 0.0048 16.5 0.0 0.008 15.8 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide-interacting protein family Gpr1_Fun34_YaaH PF01184.19 OAG44463.1 - 3.2e-31 108.6 17.2 4.8e-31 108.0 17.2 1.2 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Snf7 PF03357.21 OAG44463.1 - 4e-21 75.4 12.4 4e-21 75.4 12.4 2.3 1 1 1 2 2 2 1 Snf7 Ac76 PF05814.11 OAG44463.1 - 0.2 11.7 1.3 0.6 10.2 1.3 1.8 1 0 0 1 1 1 0 Orf76 (Ac76) DUF2244 PF10003.9 OAG44463.1 - 6.9 6.3 9.5 27 4.4 9.5 1.9 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) HypA PF01155.19 OAG44464.1 - 0.0039 17.2 1.7 0.009 16.0 0.1 2.0 2 0 0 2 2 2 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA SAP PF02037.27 OAG44464.1 - 0.012 15.4 0.0 0.023 14.5 0.0 1.5 1 0 0 1 1 1 0 SAP domain zf-WRNIP1_ubi PF18279.1 OAG44464.1 - 0.013 16.1 0.9 0.013 16.1 0.9 2.9 3 0 0 3 3 3 0 Werner helicase-interacting protein 1 ubiquitin-binding domain Sgf11 PF08209.11 OAG44464.1 - 0.24 11.0 5.5 0.045 13.3 1.4 1.9 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) zinc-ribbons_6 PF07191.12 OAG44464.1 - 0.57 10.2 6.2 0.59 10.2 0.3 2.3 2 0 0 2 2 2 0 zinc-ribbons zf-C3HC4_3 PF13920.6 OAG44464.1 - 1.7 8.5 8.2 0.59 10.0 0.5 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 OAG44464.1 - 1.8 8.4 8.3 0.27 11.1 2.6 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain TRAPPC-Trs85 PF12739.7 OAG44465.1 - 2.9e-109 365.7 1.9 1.9e-108 363.0 1.0 2.0 2 0 0 2 2 2 2 ER-Golgi trafficking TRAPP I complex 85 kDa subunit Mito_carr PF00153.27 OAG44466.1 - 5.4e-65 215.4 1.9 3.2e-21 75.0 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 OAG44466.1 - 5.4e-22 78.0 4.0 1.4e-11 44.7 0.5 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 OAG44466.1 - 2.1e-19 67.5 6.6 7.9e-07 28.2 0.6 4.6 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.6 OAG44466.1 - 6.9e-18 63.0 4.4 7.3e-05 22.4 0.0 4.4 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 OAG44466.1 - 1e-17 62.7 4.9 7.7e-07 28.3 0.7 3.6 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 OAG44466.1 - 2.7e-11 43.1 1.6 0.00031 20.5 0.1 3.5 2 2 2 4 4 4 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 OAG44466.1 - 7.2e-09 36.0 0.2 9.3e-05 22.7 0.1 2.3 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 OAG44466.1 - 0.003 17.5 4.3 0.022 14.7 0.4 2.9 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.6 OAG44466.1 - 0.013 15.4 1.2 13 5.7 0.0 3.7 5 0 0 5 5 5 0 EF hand Serine_protease PF18405.1 OAG44466.1 - 0.029 13.5 0.1 6.6 5.8 0.0 3.0 3 0 0 3 3 3 0 Gammaproteobacterial serine protease EF-hand_11 PF08976.11 OAG44466.1 - 0.07 14.0 0.3 0.33 11.8 0.0 2.2 2 1 0 2 2 2 0 EF-hand domain DUF5580 PF17743.1 OAG44466.1 - 0.12 10.8 0.0 0.19 10.2 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5580) Dockerin_1 PF00404.18 OAG44466.1 - 0.14 12.4 0.9 20 5.5 0.1 2.7 3 0 0 3 3 3 0 Dockerin type I domain Cyclin_N PF00134.23 OAG44467.1 - 6.9e-13 48.5 1.9 3.6e-11 42.9 0.3 2.6 2 1 1 3 3 3 2 Cyclin, N-terminal domain AAA_35 PF14516.6 OAG44467.1 - 0.028 13.3 1.6 0.16 10.8 0.4 2.0 2 0 0 2 2 2 0 AAA-like domain TFCD_C PF12612.8 OAG44468.1 - 1.1e-21 77.5 0.8 3.4e-21 75.9 0.3 2.2 2 0 0 2 2 2 1 Tubulin folding cofactor D C terminal HEAT_2 PF13646.6 OAG44468.1 - 0.0022 18.3 1.6 0.07 13.5 0.1 3.7 3 1 0 3 3 3 1 HEAT repeats HEAT PF02985.22 OAG44468.1 - 0.0053 16.9 10.6 0.042 14.1 0.0 5.8 6 0 0 6 6 6 1 HEAT repeat HEAT_EZ PF13513.6 OAG44468.1 - 0.028 14.9 1.9 0.75 10.4 0.0 4.4 3 1 1 4 4 4 0 HEAT-like repeat Vac14_Fab1_bd PF12755.7 OAG44468.1 - 0.056 14.0 0.0 7.5 7.2 0.0 3.0 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region IFRD PF05004.13 OAG44468.1 - 0.27 10.3 7.2 0.037 13.1 0.9 2.6 4 0 0 4 4 4 0 Interferon-related developmental regulator (IFRD) DNA_pol_B PF00136.21 OAG44470.1 - 4.3e-146 487.2 3.9 5.9e-146 486.8 3.9 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 OAG44470.1 - 1.3e-81 274.4 0.1 2.3e-81 273.6 0.1 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 OAG44470.1 - 7.2e-19 68.0 6.0 1.7e-18 66.9 6.0 1.7 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta RNase_H_2 PF13482.6 OAG44470.1 - 0.00091 19.3 0.2 0.0057 16.7 0.2 2.3 1 1 0 1 1 1 1 RNase_H superfamily DNA_pol_B_exo2 PF10108.9 OAG44470.1 - 0.0014 18.4 0.1 0.0031 17.2 0.1 1.5 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB C1_1 PF00130.22 OAG44470.1 - 0.077 12.9 7.7 0.37 10.7 1.3 2.5 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Rho_GDI PF02115.17 OAG44471.1 - 1.3e-62 211.1 0.0 1.4e-62 210.9 0.0 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor Metallophos PF00149.28 OAG44472.1 - 1.8e-36 126.6 0.4 2.3e-36 126.2 0.4 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 OAG44472.1 - 0.0083 16.6 0.2 0.02 15.3 0.2 1.7 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain SUIM_assoc PF16619.5 OAG44472.1 - 0.046 13.8 2.3 0.072 13.2 2.3 1.2 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 adh_short PF00106.25 OAG44474.1 - 5.6e-49 166.3 0.1 7.5e-49 165.8 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG44474.1 - 1e-32 113.6 0.1 1.2e-32 113.3 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG44474.1 - 2.8e-12 46.9 0.0 9.4e-12 45.2 0.0 1.7 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OAG44474.1 - 0.00092 18.4 0.2 0.0088 15.2 0.1 2.0 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 OAG44474.1 - 0.0015 18.7 0.1 0.0028 17.9 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain THF_DHG_CYH_C PF02882.19 OAG44474.1 - 0.085 12.2 0.5 0.45 9.8 0.1 2.3 3 0 0 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain RasGEF PF00617.19 OAG44475.1 - 3.5e-57 193.5 0.9 6.4e-57 192.6 0.9 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 OAG44475.1 - 8.5e-29 99.9 0.1 2.3e-28 98.5 0.1 1.8 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.28 OAG44475.1 - 1.7e-14 53.2 0.1 5e-14 51.6 0.1 1.9 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 OAG44475.1 - 3.3e-13 49.3 0.1 7.8e-13 48.1 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 OAG44475.1 - 7.1e-10 38.4 0.0 1.5e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.26 OAG44475.1 - 0.00034 20.6 0.0 0.0011 19.0 0.0 1.9 1 0 0 1 1 1 1 WW domain FAD_binding_3 PF01494.19 OAG44476.1 - 1.1e-22 80.8 0.4 2.1e-22 79.8 0.4 1.5 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAG44476.1 - 6e-11 42.5 8.6 8.9e-07 28.8 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG44476.1 - 1.5e-08 34.2 6.4 0.0014 17.9 0.1 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAG44476.1 - 2.7e-08 34.3 2.1 0.00057 20.4 1.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG44476.1 - 2.5e-07 30.8 1.0 7e-07 29.4 1.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 OAG44476.1 - 7.1e-06 25.6 3.0 0.016 14.5 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Trp_halogenase PF04820.14 OAG44476.1 - 0.00011 21.2 3.7 0.3 9.9 2.6 2.4 2 0 0 2 2 2 2 Tryptophan halogenase FAD_oxidored PF12831.7 OAG44476.1 - 0.00048 19.6 0.8 0.00073 19.0 0.8 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 OAG44476.1 - 0.0015 17.3 5.0 0.031 13.0 2.8 2.1 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 OAG44476.1 - 0.0015 17.7 8.5 0.0027 16.9 6.2 2.0 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.6 OAG44476.1 - 0.0016 17.7 2.9 0.067 12.4 1.4 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAG44476.1 - 0.0048 16.2 1.2 0.0081 15.4 1.2 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 OAG44476.1 - 0.028 14.4 3.3 0.32 11.0 0.1 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding SE PF08491.10 OAG44476.1 - 0.037 13.1 0.0 0.086 11.9 0.0 1.5 1 1 0 1 1 1 0 Squalene epoxidase GIDA PF01134.22 OAG44476.1 - 0.049 12.7 4.9 0.069 12.2 4.9 1.4 1 1 0 1 1 1 0 Glucose inhibited division protein A Fungal_trans PF04082.18 OAG44477.1 - 4.2e-16 58.8 2.1 6.9e-16 58.1 2.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.6 OAG44477.1 - 1.3e-06 28.6 16.9 2.8e-05 24.3 5.9 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 OAG44477.1 - 4.2e-05 23.8 14.6 0.005 17.2 5.2 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAG44477.1 - 0.00033 21.2 12.6 0.12 13.2 3.9 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 OAG44477.1 - 0.12 13.1 0.5 2.4 8.9 0.3 2.6 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats PyrI_C PF02748.15 OAG44477.1 - 0.78 9.7 3.7 0.24 11.3 0.4 1.8 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_jaz PF12171.8 OAG44477.1 - 2.2 8.7 7.3 0.63 10.4 3.8 2.0 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.10 OAG44477.1 - 2.4 8.4 4.7 6.8 6.9 4.7 1.8 1 0 0 1 1 1 0 Zinc ribbon domain DivIC PF04977.15 OAG44478.1 - 3.8e-05 23.4 1.5 3.8e-05 23.4 1.5 3.5 4 0 0 4 4 4 1 Septum formation initiator bZIP_2 PF07716.15 OAG44478.1 - 0.0025 17.9 25.8 0.14 12.2 2.7 4.5 4 1 1 5 5 5 4 Basic region leucine zipper PI3K_P85_iSH2 PF16454.5 OAG44478.1 - 0.0082 15.7 0.9 0.0082 15.7 0.9 2.8 3 0 0 3 3 3 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain ADIP PF11559.8 OAG44478.1 - 0.011 15.8 2.3 0.011 15.8 2.3 3.4 4 0 0 4 4 4 0 Afadin- and alpha -actinin-Binding bZIP_1 PF00170.21 OAG44478.1 - 0.019 15.0 17.4 1 9.5 4.6 3.6 3 0 0 3 3 3 0 bZIP transcription factor HALZ PF02183.18 OAG44478.1 - 0.021 15.1 9.9 0.035 14.3 1.1 2.9 2 1 0 2 2 2 0 Homeobox associated leucine zipper Get5_C PF18514.1 OAG44478.1 - 0.021 14.6 0.0 1.2 9.0 0.0 2.5 2 0 0 2 2 2 0 Get5 C-terminal domain ZapB PF06005.12 OAG44478.1 - 0.032 14.7 2.8 0.032 14.7 2.8 3.3 3 0 0 3 3 3 0 Cell division protein ZapB DUF4140 PF13600.6 OAG44478.1 - 0.053 14.0 8.6 0.33 11.4 0.4 3.6 4 0 0 4 4 3 0 N-terminal domain of unknown function (DUF4140) ABC_tran_CTD PF16326.5 OAG44478.1 - 0.086 13.1 9.7 0.98 9.7 3.3 3.4 3 0 0 3 3 3 0 ABC transporter C-terminal domain GIT_CC PF16559.5 OAG44478.1 - 0.48 10.3 8.4 9.4 6.2 0.4 3.6 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor KELK PF15796.5 OAG44478.1 - 0.58 10.7 10.3 6 7.4 2.6 3.2 3 0 0 3 3 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase NUDE_C PF04880.13 OAG44478.1 - 0.67 10.4 10.1 5.9 7.3 3.9 2.6 2 0 0 2 2 2 0 NUDE protein, C-terminal conserved region UPF0449 PF15136.6 OAG44478.1 - 0.9 10.0 8.4 1.9 9.0 0.6 3.8 4 0 0 4 4 4 0 Uncharacterised protein family UPF0449 TSC22 PF01166.18 OAG44478.1 - 1 9.7 10.2 6 7.3 0.8 3.3 3 0 0 3 3 3 0 TSC-22/dip/bun family zf-CpG_bind_C PF12269.8 OAG44478.1 - 1.2 8.8 10.6 0.14 11.9 0.6 3.1 3 0 0 3 3 3 0 CpG binding protein zinc finger C terminal domain FlaC_arch PF05377.11 OAG44478.1 - 2.5 8.6 6.5 2.8 8.4 0.3 2.9 3 0 0 3 3 2 0 Flagella accessory protein C (FlaC) HalX PF08663.10 OAG44478.1 - 3.9 7.9 14.7 1.2 9.5 0.5 3.7 3 0 0 3 3 3 0 HalX domain KfrA_N PF11740.8 OAG44478.1 - 4.7 7.9 14.9 0.5 11.1 0.9 3.5 4 0 0 4 4 3 0 Plasmid replication region DNA-binding N-term YabA PF06156.13 OAG44478.1 - 6.2 7.5 14.4 1.1 10.0 1.0 3.3 4 0 0 4 4 3 0 Initiation control protein YabA UQ_con PF00179.26 OAG44479.1 - 1.8e-17 63.3 0.0 2.9e-17 62.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme FAM220 PF15487.6 OAG44479.1 - 0.04 13.5 0.6 0.061 13.0 0.6 1.2 1 0 0 1 1 1 0 FAM220 family AA_permease_2 PF13520.6 OAG44480.1 - 7.2e-43 147.0 52.5 8.7e-43 146.7 52.5 1.0 1 0 0 1 1 1 1 Amino acid permease Fungal_trans_2 PF11951.8 OAG44481.1 - 6.3e-34 117.4 1.9 1.3e-33 116.3 1.9 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG44481.1 - 2.4e-11 43.6 7.4 7.2e-11 42.0 7.4 1.9 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain aGPT-Pplase3 PF18746.1 OAG44481.1 - 0.032 13.6 0.0 0.059 12.7 0.0 1.3 1 0 0 1 1 1 0 Alpha-glutamyl/putrescinyl thymine pyrophosphorylase clade 3 PhyH PF05721.13 OAG44482.1 - 3.1e-20 73.3 0.0 4.1e-20 72.9 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Amino_oxidase PF01593.24 OAG44483.1 - 7.9e-48 163.9 0.0 9.2e-48 163.6 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OAG44483.1 - 1.5e-11 44.3 0.4 4e-11 43.0 0.4 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAG44483.1 - 9.6e-08 32.0 0.1 1.6e-07 31.3 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 OAG44483.1 - 3.2e-06 26.7 0.0 8.7e-06 25.3 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OAG44483.1 - 3.4e-06 26.4 0.1 5.2e-06 25.8 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 OAG44483.1 - 4.7e-06 25.6 0.0 1.1e-05 24.3 0.0 1.6 2 0 0 2 2 2 1 HI0933-like protein Lycopene_cycl PF05834.12 OAG44483.1 - 1.6e-05 24.2 0.1 0.00021 20.5 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 OAG44483.1 - 2.7e-05 23.6 0.0 4.7e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAG44483.1 - 3.1e-05 23.3 0.0 5.4e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 OAG44483.1 - 5.2e-05 22.7 0.3 0.001 18.4 0.2 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 OAG44483.1 - 0.0038 17.7 0.1 0.0072 16.9 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OAG44483.1 - 0.0069 15.5 0.0 0.012 14.7 0.0 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A GDI PF00996.18 OAG44483.1 - 0.026 13.0 0.0 0.045 12.3 0.0 1.3 1 0 0 1 1 1 0 GDP dissociation inhibitor UDPG_MGDP_dh_N PF03721.14 OAG44483.1 - 0.045 13.3 0.0 0.072 12.6 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Shikimate_DH PF01488.20 OAG44483.1 - 0.22 11.6 0.0 0.42 10.7 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Ribonuc_L-PSP PF01042.21 OAG44484.1 - 2.3e-10 40.5 0.1 2.7e-10 40.3 0.1 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP DHHC PF01529.20 OAG44485.1 - 1.6e-36 125.3 7.9 1.6e-36 125.3 7.9 1.5 2 0 0 2 2 2 1 DHHC palmitoyltransferase Yip1 PF04893.17 OAG44485.1 - 0.022 14.5 0.5 0.022 14.5 0.5 1.6 2 0 0 2 2 2 0 Yip1 domain Acetyltransf_7 PF13508.7 OAG44486.1 - 9.1e-07 29.2 0.0 1.5e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAG44486.1 - 1.8e-06 28.2 0.0 2.9e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 OAG44486.1 - 8.8e-05 22.6 0.1 0.00025 21.1 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OAG44486.1 - 0.0002 21.3 0.0 0.00031 20.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 OAG44486.1 - 0.0025 17.9 0.0 0.0053 16.9 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 OAG44486.1 - 0.0036 17.2 0.0 0.0072 16.3 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Sugar_tr PF00083.24 OAG44487.1 - 8.4e-116 387.5 22.1 9.6e-116 387.3 22.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG44487.1 - 8.7e-20 70.9 46.9 3.4e-17 62.4 10.9 2.0 1 1 0 2 2 2 2 Major Facilitator Superfamily DUF2264 PF10022.9 OAG44488.1 - 1.7e-134 448.4 0.4 2e-134 448.1 0.4 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) BNR PF02012.20 OAG44488.1 - 0.09 12.8 0.0 0.49 10.6 0.0 2.4 1 0 0 1 1 1 0 BNR/Asp-box repeat RPA_C PF08784.11 OAG44489.1 - 3.5e-18 66.2 0.0 6.1e-18 65.4 0.0 1.4 1 0 0 1 1 1 1 Replication protein A C terminal tRNA_anti-codon PF01336.25 OAG44489.1 - 8.2e-08 32.1 0.1 1.8e-07 31.0 0.0 1.6 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain HTH_36 PF13730.6 OAG44489.1 - 0.14 12.1 0.0 0.34 10.9 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain DEAD PF00270.29 OAG44490.1 - 1.3e-50 171.6 0.2 3.9e-50 170.0 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAG44490.1 - 2.6e-24 85.7 0.0 2.8e-23 82.4 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 OAG44490.1 - 1.3e-20 73.4 3.9 3.8e-20 71.9 3.9 1.9 1 0 0 1 1 1 1 DBP10CT (NUC160) domain PBP_N PF17093.5 OAG44491.1 - 0.043 14.1 2.3 0.12 12.6 2.3 1.7 1 0 0 1 1 1 0 Penicillin-binding protein N-terminus DUF2788 PF10981.8 OAG44491.1 - 0.1 12.6 0.3 0.1 12.6 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2788) LDB19 PF13002.7 OAG44492.1 - 1.5e-50 171.6 0.4 4.6e-50 170.0 0.4 1.7 2 0 0 2 2 2 1 Arrestin_N terminal like Arrestin_N PF00339.29 OAG44492.1 - 0.0013 18.8 0.0 0.011 15.7 0.0 2.5 2 1 1 3 3 3 1 Arrestin (or S-antigen), N-terminal domain DUF4606 PF15379.6 OAG44492.1 - 0.072 13.3 0.0 0.072 13.3 0.0 2.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4606) Oxidored_molyb PF00174.19 OAG44493.1 - 2.8e-48 163.8 0.0 5.7e-48 162.8 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 OAG44493.1 - 1.2e-20 74.0 3.8 2.6e-20 72.8 3.8 1.5 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Epimerase PF01370.21 OAG44494.1 - 2.8e-13 49.9 0.0 4.1e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OAG44494.1 - 4.1e-10 39.1 0.0 5.9e-10 38.6 0.0 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 OAG44494.1 - 2e-09 37.0 0.0 2.8e-07 30.0 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein GDP_Man_Dehyd PF16363.5 OAG44494.1 - 0.00012 21.7 0.0 0.00023 20.7 0.0 1.5 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase DUF3390 PF11870.8 OAG44494.1 - 0.02 15.3 0.0 0.067 13.6 0.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3390) NmrA PF05368.13 OAG44494.1 - 0.06 12.9 0.0 0.085 12.4 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family KR PF08659.10 OAG44494.1 - 0.17 11.8 0.2 0.5 10.2 0.2 1.9 1 1 0 1 1 1 0 KR domain SNF2_N PF00176.23 OAG44495.1 - 1.8e-71 240.7 0.0 2.4e-71 240.3 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.11 OAG44495.1 - 6.2e-24 83.8 0.0 1.3e-23 82.7 0.0 1.6 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.31 OAG44495.1 - 7.8e-13 48.7 0.0 1.6e-12 47.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.6 OAG44495.1 - 9.1e-05 22.2 5.3 0.00018 21.3 5.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OAG44495.1 - 0.00037 20.3 4.7 0.00093 19.0 4.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAG44495.1 - 0.00047 20.0 8.0 0.00095 19.0 8.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAG44495.1 - 0.00069 19.6 7.1 0.0015 18.5 7.1 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 OAG44495.1 - 0.0039 17.1 6.5 0.0082 16.1 6.5 1.6 1 0 0 1 1 1 1 zinc-RING finger domain UBA_4 PF14555.6 OAG44495.1 - 0.0087 15.9 0.1 0.023 14.5 0.1 1.7 1 0 0 1 1 1 1 UBA-like domain zf-RING_2 PF13639.6 OAG44495.1 - 0.025 14.9 7.4 0.06 13.7 7.4 1.7 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_4 PF15227.6 OAG44495.1 - 1.5 9.0 5.6 3.8 7.7 5.6 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 OAG44495.1 - 8.2 6.4 7.6 39 4.2 7.8 2.0 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 SQS_PSY PF00494.19 OAG44496.1 - 5.2e-50 170.4 0.0 9.7e-50 169.5 0.0 1.4 1 1 0 1 1 1 1 Squalene/phytoene synthase UPF0052 PF01933.18 OAG44497.1 - 6.8e-63 212.6 0.0 9.4e-63 212.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 CorA PF01544.18 OAG44498.1 - 6e-28 98.0 5.9 4.5e-20 72.1 0.4 3.4 3 1 0 3 3 3 3 CorA-like Mg2+ transporter protein FTA2 PF13095.6 OAG44499.1 - 1.7e-22 80.2 0.0 2.8e-22 79.4 0.0 1.3 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 OAG44499.1 - 4.7e-05 22.8 0.0 7.5e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 OAG44499.1 - 0.00013 21.4 0.0 0.00071 19.0 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain APH PF01636.23 OAG44499.1 - 0.00088 19.3 0.0 0.47 10.3 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 OAG44499.1 - 0.0014 18.3 0.0 0.0027 17.3 0.0 1.5 2 0 0 2 2 2 1 RIO1 family Pkinase_Tyr PF07714.17 OAG44499.1 - 0.24 10.7 0.0 0.37 10.0 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase adh_short_C2 PF13561.6 OAG44500.1 - 1.4e-52 178.6 0.0 2.3e-51 174.6 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG44500.1 - 3.7e-40 137.5 0.0 3.6e-39 134.3 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG44500.1 - 5.3e-12 46.0 0.1 1.3e-11 44.8 0.0 1.6 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 OAG44500.1 - 2.3e-05 24.0 0.0 6.8e-05 22.5 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OAG44500.1 - 0.094 11.7 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF3425 PF11905.8 OAG44501.1 - 4.3e-13 49.3 0.0 5.2e-11 42.6 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF3425) TRI12 PF06609.13 OAG44502.1 - 2.4e-143 478.7 28.6 7.8e-87 292.1 9.4 2.1 1 1 1 2 2 2 2 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG44502.1 - 2e-11 43.5 16.9 2e-11 43.5 16.9 3.3 3 1 0 3 3 3 1 Major Facilitator Superfamily bZIP_1 PF00170.21 OAG44502.1 - 0.00052 20.1 7.2 0.0012 18.9 7.2 1.6 1 0 0 1 1 1 1 bZIP transcription factor DUF4763 PF15960.5 OAG44502.1 - 0.021 14.1 0.4 0.038 13.3 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) DUF677 PF05055.12 OAG44502.1 - 0.18 10.6 0.5 0.38 9.6 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF677) DUF3040 PF11239.8 OAG44502.1 - 0.24 11.7 0.0 0.24 11.7 0.0 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) adh_short_C2 PF13561.6 OAG44503.1 - 3.6e-48 164.2 0.0 6.5e-48 163.3 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG44503.1 - 7.3e-41 139.8 0.0 1.2e-40 139.0 0.0 1.3 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG44503.1 - 1.1e-11 44.9 0.2 2.7e-11 43.7 0.0 1.6 2 0 0 2 2 2 1 KR domain 3Beta_HSD PF01073.19 OAG44503.1 - 0.026 13.5 0.1 0.057 12.4 0.1 1.5 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family FMO-like PF00743.19 OAG44504.1 - 3.1e-20 72.1 0.1 1.9e-19 69.5 0.1 2.1 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 OAG44504.1 - 2.5e-09 36.8 0.0 4.2e-08 32.7 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 OAG44504.1 - 6.6e-09 35.9 0.0 1.5e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAG44504.1 - 2.4e-06 27.0 0.0 0.0003 20.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG44504.1 - 5.1e-05 22.7 0.1 0.00055 19.3 0.1 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAG44504.1 - 0.008 16.2 0.0 0.71 9.8 0.0 3.5 3 1 1 4 4 4 1 FAD-NAD(P)-binding Thi4 PF01946.17 OAG44504.1 - 0.037 13.3 0.0 0.12 11.6 0.0 1.7 2 0 0 2 2 2 0 Thi4 family Beta-lactamase PF00144.24 OAG44505.1 - 1.3e-37 129.8 1.6 8.9e-37 127.1 1.6 1.9 1 1 0 1 1 1 1 Beta-lactamase Beta-lactamase2 PF13354.6 OAG44505.1 - 0.068 12.8 0.0 2.3 7.7 0.0 2.4 2 1 0 2 2 2 0 Beta-lactamase enzyme family p450 PF00067.22 OAG44506.1 - 5.6e-46 157.2 0.0 7.7e-46 156.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF3433 PF11915.8 OAG44506.1 - 8.6e-12 45.4 14.7 2.9e-08 34.1 2.2 3.5 4 0 0 4 4 4 2 Protein of unknown function (DUF3433) DUF3425 PF11905.8 OAG44507.1 - 7.7e-11 42.0 2.9 9e-11 41.8 0.8 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3425) DUF4527 PF15030.6 OAG44507.1 - 0.0094 15.4 0.3 0.023 14.2 0.3 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF4527) ABC_tran_Xtn PF12848.7 OAG44507.1 - 0.022 14.8 5.2 0.039 14.0 5.2 1.3 1 0 0 1 1 1 0 ABC transporter OrfB_Zn_ribbon PF07282.11 OAG44507.1 - 0.16 11.9 1.1 0.36 10.8 1.1 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain GAS PF13851.6 OAG44507.1 - 0.18 11.2 0.3 0.28 10.5 0.3 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding bZIP_1 PF00170.21 OAG44507.1 - 0.5 10.5 4.8 0.99 9.5 4.8 1.5 1 0 0 1 1 1 0 bZIP transcription factor NUDIX PF00293.28 OAG44508.1 - 1.3e-07 31.7 0.0 2.2e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain DUF4743 PF15916.5 OAG44508.1 - 0.0017 18.3 0.0 0.0025 17.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4743) PALP PF00291.25 OAG44509.1 - 1e-74 251.6 0.1 1.4e-74 251.2 0.1 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 OAG44509.1 - 3.1e-41 139.1 0.0 2.9e-20 71.8 0.0 2.3 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase HIG_1_N PF04588.13 OAG44510.1 - 6.7e-24 83.9 0.3 9.4e-24 83.4 0.3 1.2 1 0 0 1 1 1 1 Hypoxia induced protein conserved region MAS20 PF02064.15 OAG44510.1 - 0.048 13.7 3.1 0.089 12.9 3.1 1.5 1 0 0 1 1 1 0 MAS20 protein import receptor VSG_B PF13206.6 OAG44510.1 - 0.11 11.7 5.3 0.13 11.5 5.3 1.1 1 0 0 1 1 1 0 Trypanosomal VSG domain DUF1835 PF08874.10 OAG44510.1 - 0.13 12.5 2.5 0.27 11.4 2.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1835) TMPIT PF07851.13 OAG44510.1 - 2.7 7.2 7.2 13 4.9 0.0 2.0 1 1 1 2 2 2 0 TMPIT-like protein Complex1_LYR PF05347.15 OAG44511.1 - 3e-13 49.6 0.2 7.5e-13 48.3 0.2 1.7 1 0 0 1 1 1 1 Complex 1 protein (LYR family) zf-C3HC4 PF00097.25 OAG44511.1 - 8.8e-05 22.3 2.2 0.00021 21.1 2.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAG44511.1 - 0.00012 22.4 5.2 0.00034 20.9 5.2 1.9 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 OAG44511.1 - 0.0002 21.1 4.8 0.00043 20.1 4.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OAG44511.1 - 0.00031 20.5 1.7 0.00073 19.3 1.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAG44511.1 - 0.0045 17.0 6.6 0.0045 17.0 6.6 2.1 2 0 0 2 2 2 1 RING-type zinc-finger Complex1_LYR_2 PF13233.6 OAG44511.1 - 0.1 13.3 0.1 0.3 11.8 0.1 1.8 1 0 0 1 1 1 0 Complex1_LYR-like zf-RING_5 PF14634.6 OAG44511.1 - 0.11 12.5 4.9 0.23 11.4 4.9 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_4 PF15227.6 OAG44511.1 - 0.11 12.7 4.0 0.33 11.1 4.1 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 OAG44511.1 - 0.13 12.1 5.3 0.045 13.6 2.0 1.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 OAG44511.1 - 0.19 11.5 4.0 0.52 10.1 4.0 1.7 1 0 0 1 1 1 0 RING-like zinc finger Pyr_redox_2 PF07992.14 OAG44513.1 - 3.6e-14 52.7 0.0 5.9e-11 42.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 OAG44513.1 - 2.3e-12 46.1 0.1 8.3e-11 41.0 0.0 2.2 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 OAG44513.1 - 5.7e-10 38.9 0.0 1.6e-08 34.1 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 OAG44513.1 - 3.3e-09 36.4 0.0 1.9e-07 30.6 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG44513.1 - 6.7e-09 35.9 0.0 1.4e-07 31.6 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 OAG44513.1 - 0.00099 18.3 0.0 0.0022 17.1 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAG44513.1 - 0.0013 18.4 1.4 0.12 12.0 0.0 3.4 3 2 1 4 4 4 1 FAD dependent oxidoreductase Thi4 PF01946.17 OAG44513.1 - 0.0045 16.3 0.2 0.014 14.6 0.0 1.8 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.12 OAG44513.1 - 0.017 14.2 0.0 0.11 11.6 0.0 2.2 2 1 0 2 2 2 0 Lycopene cyclase protein GIDA PF01134.22 OAG44513.1 - 0.16 11.0 0.2 3.8 6.5 0.0 2.4 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_9 PF13454.6 OAG44513.1 - 0.18 11.8 1.9 27 4.7 0.1 3.8 3 1 0 3 3 3 0 FAD-NAD(P)-binding HI0933_like PF03486.14 OAG44513.1 - 0.2 10.3 0.2 5.5 5.6 0.0 2.9 3 0 0 3 3 3 0 HI0933-like protein WD40 PF00400.32 OAG44515.1 - 2.2e-21 75.7 11.5 3e-06 27.9 0.1 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG44515.1 - 9.5e-09 35.4 0.0 0.076 13.3 0.0 4.5 4 1 0 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OAG44515.1 - 0.0079 16.1 0.0 4.2 7.2 0.0 2.6 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Tom37 PF10568.9 OAG44516.1 - 1.5e-38 131.9 0.3 3.1e-38 130.9 0.0 1.7 2 0 0 2 2 2 1 Outer mitochondrial membrane transport complex protein GST_C_6 PF17171.4 OAG44516.1 - 1.1e-11 44.3 0.0 3.5e-10 39.5 0.0 2.8 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 OAG44516.1 - 1.1e-09 38.9 0.0 2.1e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C PF00043.25 OAG44516.1 - 1.2e-05 25.5 0.0 2.6e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OAG44516.1 - 5.1e-05 23.2 0.0 0.00041 20.3 0.0 2.4 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OAG44516.1 - 0.019 15.2 0.0 0.087 13.0 0.0 2.0 1 1 1 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 OAG44516.1 - 0.15 12.4 0.0 0.3 11.5 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Zip PF02535.22 OAG44517.1 - 1.3e-68 231.7 4.6 1.4e-68 231.5 4.6 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter bZIP_1 PF00170.21 OAG44518.1 - 0.0015 18.6 11.8 1.3 9.2 11.8 2.3 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 OAG44518.1 - 0.58 10.3 14.0 2.8 8.1 3.9 2.4 1 1 2 3 3 3 0 Basic region leucine zipper Spc7 PF08317.11 OAG44518.1 - 0.83 8.5 4.2 1.2 7.9 4.2 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Methyltransf_31 PF13847.6 OAG44519.1 - 4.7e-25 88.2 0.0 7.2e-25 87.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG44519.1 - 5.2e-20 71.9 0.0 9.6e-20 71.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG44519.1 - 1.9e-19 70.1 0.0 3.9e-19 69.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAG44519.1 - 6.4e-13 48.9 0.0 1e-12 48.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG44519.1 - 3.5e-11 43.7 0.0 5.7e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAG44519.1 - 1.9e-10 40.5 0.0 3.1e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.13 OAG44519.1 - 3.6e-06 26.6 0.0 5.6e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) UPF0020 PF01170.18 OAG44519.1 - 1.4e-05 24.8 0.0 2.3e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 MTS PF05175.14 OAG44519.1 - 0.00095 18.8 0.0 0.0015 18.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_8 PF05148.15 OAG44519.1 - 0.0073 16.2 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 Hypothetical methyltransferase PCMT PF01135.19 OAG44519.1 - 0.06 13.1 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.20 OAG44519.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase CheR PF01739.18 OAG44519.1 - 0.16 11.4 0.0 4.9 6.6 0.0 2.2 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain Tautomerase_3 PF14832.6 OAG44520.1 - 8.7e-09 35.7 0.0 1.1e-08 35.3 0.0 1.2 1 0 0 1 1 1 1 Putative oxalocrotonate tautomerase enzyme DUF1175 PF06672.11 OAG44520.1 - 0.094 12.4 0.1 0.12 12.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1175) YTH PF04146.15 OAG44521.1 - 1.4e-60 204.0 0.0 5.8e-60 202.0 0.0 2.0 2 0 0 2 2 2 1 YT521-B-like domain RRM_1 PF00076.22 OAG44521.1 - 1.1e-06 28.3 0.0 2e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OAG44521.1 - 0.035 14.0 0.0 0.065 13.1 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif ArfGap PF01412.18 OAG44522.1 - 4.5e-32 110.6 0.0 4.5e-32 110.6 0.0 2.6 3 0 0 3 3 3 1 Putative GTPase activating protein for Arf BAR_3 PF16746.5 OAG44522.1 - 1.5e-19 70.7 16.0 3.2e-19 69.6 16.0 1.5 1 0 0 1 1 1 1 BAR domain of APPL family PH PF00169.29 OAG44522.1 - 1.4e-13 51.2 0.3 3.8e-13 49.9 0.3 1.8 1 0 0 1 1 1 1 PH domain PH_13 PF16652.5 OAG44522.1 - 0.016 15.0 0.7 0.056 13.3 0.0 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain PH_11 PF15413.6 OAG44522.1 - 0.036 14.5 1.6 0.13 12.7 0.4 2.5 2 0 0 2 2 2 0 Pleckstrin homology domain ANAPC9 PF12856.7 OAG44522.1 - 0.056 13.6 1.3 0.14 12.3 1.3 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 9 DZR PF12773.7 OAG44522.1 - 0.16 12.0 0.1 0.42 10.7 0.1 1.6 1 0 0 1 1 1 0 Double zinc ribbon DUF948 PF06103.11 OAG44522.1 - 7.6 6.9 6.2 24 5.3 0.1 2.8 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF4937 PF16291.5 OAG44523.1 - 0.0097 16.1 0.1 1.2 9.4 0.1 3.1 2 1 1 3 3 3 1 Domain of unknown function (DUF4937 Mannosyl_trans3 PF11051.8 OAG44524.1 - 0.013 14.8 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 Mannosyltransferase putative Glyco_transf_8 PF01501.20 OAG44524.1 - 0.022 14.3 0.0 0.033 13.8 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 8 Glyco_transf_25 PF01755.17 OAG44525.1 - 6.5e-09 35.9 0.0 2.6e-08 34.0 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase family 25 (LPS biosynthesis protein) RRM_1 PF00076.22 OAG44526.1 - 2.7e-09 36.7 0.1 7.4e-09 35.3 0.1 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 OAG44526.1 - 0.15 12.2 0.2 0.72 10.0 0.2 2.0 1 1 0 1 1 1 0 Limkain b1 Haem_degrading PF03928.14 OAG44527.1 - 1.7e-35 121.7 0.1 2e-35 121.4 0.1 1.1 1 0 0 1 1 1 1 Haem-degrading Rotamase PF00639.21 OAG44529.1 - 1.1e-24 87.2 0.0 1.7e-24 86.6 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 OAG44529.1 - 6.3e-16 59.0 0.0 8.8e-16 58.5 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.26 OAG44529.1 - 1.4e-08 34.7 3.1 2.8e-08 33.7 3.1 1.5 1 0 0 1 1 1 1 WW domain Rotamase_2 PF13145.6 OAG44529.1 - 9.3e-06 26.5 0.0 1.3e-05 26.0 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain MRI PF15325.6 OAG44529.1 - 0.07 14.2 0.6 0.12 13.5 0.5 1.4 1 1 0 1 1 1 0 Modulator of retrovirus infection Ribosomal_L14 PF00238.19 OAG44530.1 - 6.6e-48 161.8 1.9 7.3e-48 161.7 1.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Phage_antitermQ PF06530.12 OAG44530.1 - 0.11 12.4 0.1 0.2 11.6 0.1 1.4 1 0 0 1 1 1 0 Phage antitermination protein Q SET PF00856.28 OAG44531.1 - 5.6e-09 36.6 2.9 4.3e-08 33.7 0.0 2.8 3 1 0 4 4 4 1 SET domain SIS PF01380.22 OAG44531.1 - 0.073 12.9 0.1 0.15 11.9 0.1 1.4 1 0 0 1 1 1 0 SIS domain MRP-L46 PF11788.8 OAG44532.1 - 1.1e-27 97.1 0.0 2.6e-27 95.9 0.0 1.6 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 Exo_endo_phos PF03372.23 OAG44533.1 - 4.3e-06 26.4 0.0 8.9e-06 25.4 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SNF5 PF04855.12 OAG44534.1 - 7.5e-63 212.5 0.2 1.1e-61 208.7 0.2 2.2 1 1 0 1 1 1 1 SNF5 / SMARCB1 / INI1 Peptidase_M24 PF00557.24 OAG44535.1 - 1.3e-07 31.5 0.0 1.9e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 AP3D1 PF06375.11 OAG44535.1 - 0.0027 18.0 3.2 0.0057 16.9 3.2 1.5 1 0 0 1 1 1 1 AP-3 complex subunit delta-1 OAD_gamma PF04277.13 OAG44535.1 - 0.53 10.9 9.2 0.35 11.5 4.0 2.5 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain PHD PF00628.29 OAG44536.1 - 1.3e-17 63.4 14.9 7.4e-12 45.0 7.8 2.4 2 0 0 2 2 2 2 PHD-finger zf-PHD-like PF15446.6 OAG44536.1 - 0.047 13.3 8.1 0.019 14.6 2.8 2.4 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain C1_1 PF00130.22 OAG44536.1 - 0.37 10.7 12.0 3.1 7.8 1.0 2.3 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.6 OAG44536.1 - 0.5 10.0 10.6 0.025 14.1 2.7 2.7 3 0 0 3 3 3 0 PHD-finger Corona_nucleoca PF00937.18 OAG44536.1 - 5.1 6.0 9.0 0.54 9.2 0.3 2.2 2 0 0 2 2 2 0 Coronavirus nucleocapsid protein Ras PF00071.22 OAG44537.1 - 7.7e-53 178.4 0.0 9.4e-53 178.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAG44537.1 - 1.1e-18 67.5 0.0 1.6e-18 67.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAG44537.1 - 1.5e-06 27.8 0.0 2.2e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RRM_1 PF00076.22 OAG44538.1 - 7.3e-37 125.0 0.0 1.9e-11 43.6 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OAG44538.1 - 1e-15 57.4 0.0 0.0041 16.9 0.0 4.3 4 0 0 4 4 4 4 Occluded RNA-recognition motif RRM_7 PF16367.5 OAG44538.1 - 1.6e-06 28.1 0.0 0.0061 16.7 0.0 3.7 3 0 0 3 3 3 1 RNA recognition motif DUF4523 PF15023.6 OAG44538.1 - 1.8e-06 27.9 0.0 0.062 13.1 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF4523) RRM PF10378.9 OAG44538.1 - 5.9e-06 25.9 10.7 4e-05 23.2 10.7 2.5 1 1 0 1 1 1 1 Putative RRM domain RRM_3 PF08777.11 OAG44538.1 - 0.00056 19.9 0.0 0.19 11.8 0.1 3.1 3 0 0 3 3 3 1 RNA binding motif RRM_Rrp7 PF17799.1 OAG44538.1 - 0.033 14.0 0.0 1.5 8.6 0.0 3.2 2 1 2 4 4 4 0 Rrp7 RRM-like N-terminal domain RNA_bind PF08675.11 OAG44538.1 - 0.058 13.4 0.3 0.38 10.8 0.0 2.6 3 0 0 3 3 3 0 RNA binding domain Nup35_RRM_2 PF14605.6 OAG44538.1 - 0.18 11.8 0.0 65 3.6 0.0 3.6 4 0 0 4 4 4 0 Nup53/35/40-type RNA recognition motif tRNA-synt_2 PF00152.20 OAG44539.1 - 1.4e-89 300.3 0.0 3.5e-89 299.0 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 OAG44539.1 - 9.5e-10 38.3 0.0 1.6e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA_anti_2 PF13742.6 OAG44539.1 - 0.015 15.4 0.0 0.047 13.9 0.0 1.8 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain DUF4539 PF15072.6 OAG44539.1 - 0.065 13.3 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4539) Lectin_leg-like PF03388.13 OAG44540.1 - 1.2e-26 93.6 0.0 2.1e-26 92.7 0.0 1.4 1 0 0 1 1 1 1 Legume-like lectin family m_DGTX_Dc1a_b_c PF17491.2 OAG44540.1 - 0.019 15.6 0.8 0.042 14.5 0.8 1.5 1 0 0 1 1 1 0 Spider Toxins mu-diguetoxin-1 a, b and c Hemagglutinin PF00509.18 OAG44540.1 - 0.067 11.6 0.1 0.11 10.9 0.1 1.3 1 0 0 1 1 1 0 Haemagglutinin Baculo_PEP_C PF04513.12 OAG44540.1 - 0.083 12.9 1.8 0.27 11.3 1.6 1.7 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ATG16 PF08614.11 OAG44540.1 - 0.35 11.1 2.0 0.52 10.5 2.0 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Alg6_Alg8 PF03155.15 OAG44541.1 - 4.3e-174 580.0 24.8 5.1e-174 579.8 24.8 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family WAC_Acf1_DNA_bd PF10537.9 OAG44542.1 - 2e-37 127.8 0.1 7.4e-37 125.9 0.1 2.1 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal WSD PF15613.6 OAG44542.1 - 1.2e-22 80.2 0.3 1.2e-22 80.2 0.3 2.9 3 0 0 3 3 3 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DDT PF02791.17 OAG44542.1 - 2.8e-17 62.8 2.7 5e-17 62.0 2.7 1.4 1 0 0 1 1 1 1 DDT domain WHIM1 PF15612.6 OAG44542.1 - 2.3e-06 27.0 0.0 5.2e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 Arginase PF00491.21 OAG44543.1 - 3.5e-82 276.1 0.0 1.7e-81 273.8 0.0 1.7 2 0 0 2 2 2 1 Arginase family UPF0489 PF12640.7 OAG44543.1 - 0.015 15.5 0.1 0.025 14.8 0.1 1.3 1 0 0 1 1 1 0 UPF0489 domain ketoacyl-synt PF00109.26 OAG44544.1 - 1.2e-58 198.7 1.9 1.1e-57 195.5 0.2 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 OAG44544.1 - 3.9e-34 117.2 0.8 7.2e-34 116.3 0.8 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 OAG44544.1 - 2.9e-05 23.6 0.5 0.0011 18.3 0.1 2.4 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 OAG44544.1 - 0.0015 18.1 1.4 0.072 12.7 0.4 2.8 2 1 0 2 2 2 1 Thiolase, C-terminal domain Haem_oxygenas_2 PF14518.6 OAG44544.1 - 0.091 12.5 0.5 11 5.8 0.0 3.2 2 1 0 2 2 2 0 Iron-containing redox enzyme KAsynt_C_assoc PF16197.5 OAG44544.1 - 0.15 12.5 0.0 0.35 11.3 0.0 1.6 1 0 0 1 1 1 0 Ketoacyl-synthetase C-terminal extension SCA7 PF08313.12 OAG44545.1 - 5e-31 106.4 0.5 5e-31 106.4 0.5 2.1 2 0 0 2 2 2 1 SCA7, zinc-binding domain CDC45 PF02724.14 OAG44545.1 - 0.0025 16.2 9.9 0.0032 15.9 9.9 1.1 1 0 0 1 1 1 1 CDC45-like protein DUF2897 PF11446.8 OAG44545.1 - 0.049 13.5 0.3 0.049 13.5 0.3 4.0 4 2 1 5 5 5 0 Protein of unknown function (DUF2897) OrsD PF12013.8 OAG44545.1 - 0.2 12.1 2.0 0.25 11.8 0.2 2.0 2 0 0 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D DUF3537 PF12056.8 OAG44545.1 - 0.21 10.3 2.6 0.15 10.8 1.2 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3537) CDC27 PF09507.10 OAG44545.1 - 0.78 9.1 27.7 0.12 11.8 23.7 1.6 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 TLP-20 PF06088.11 OAG44545.1 - 0.94 9.4 10.7 1.1 9.1 9.8 1.5 1 1 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Herpes_LMP1 PF05297.11 OAG44545.1 - 1.8 7.7 5.2 2.6 7.2 5.2 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Presenilin PF01080.17 OAG44545.1 - 3 6.5 5.6 4.6 5.9 5.6 1.2 1 0 0 1 1 1 0 Presenilin mRNA_cap_enzyme PF01331.19 OAG44546.1 - 7.8e-56 189.0 0.5 1.1e-55 188.5 0.5 1.3 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 OAG44546.1 - 1.3e-29 102.9 0.2 6.7e-29 100.7 0.4 2.0 2 0 0 2 2 2 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.21 OAG44546.1 - 2.8e-10 40.2 0.0 4.6e-05 23.2 0.0 2.3 1 1 1 2 2 2 2 ATP dependent DNA ligase domain RNA_ligase PF09414.10 OAG44546.1 - 0.00019 21.7 0.5 0.00044 20.6 0.1 1.8 2 0 0 2 2 2 1 RNA ligase GrpB PF04229.14 OAG44546.1 - 0.022 15.0 1.9 0.022 15.0 1.9 2.0 2 0 0 2 2 2 0 GrpB protein Fungal_trans PF04082.18 OAG44547.1 - 3.6e-15 55.7 0.3 2.7e-14 52.9 0.3 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG44547.1 - 3.4e-07 30.3 7.1 6.4e-07 29.4 7.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.25 OAG44548.1 - 3.7e-17 62.4 0.0 3.2e-13 49.6 0.0 2.3 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAG44548.1 - 9.5e-08 31.9 0.0 0.00011 21.9 0.0 2.3 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG44548.1 - 0.0001 22.3 0.0 0.00021 21.3 0.0 1.5 1 0 0 1 1 1 1 KR domain HEAT PF02985.22 OAG44549.1 - 0.47 10.8 3.4 8.4 7.0 0.0 4.8 5 0 0 5 5 5 0 HEAT repeat CFEM PF05730.11 OAG44551.1 - 1.4e-10 41.1 5.6 3e-10 40.1 5.6 1.6 1 0 0 1 1 1 1 CFEM domain BSD PF03909.17 OAG44552.1 - 5.3e-18 64.8 2.3 1.4e-17 63.4 0.8 2.3 2 0 0 2 2 2 1 BSD domain DUF4407 PF14362.6 OAG44552.1 - 1.1 8.6 5.2 2.3 7.5 5.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF327 PF03885.13 OAG44552.1 - 3.8 7.5 8.4 0.98 9.4 0.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF327) Suf PF05843.14 OAG44552.1 - 5.2 7.0 10.4 0.032 14.2 0.8 2.1 2 1 0 2 2 2 0 Suppressor of forked protein (Suf) Ank_2 PF12796.7 OAG44553.1 - 3.7e-61 203.7 9.4 1.8e-10 41.3 0.2 9.3 7 1 2 10 10 10 7 Ankyrin repeats (3 copies) DNA_ligase_A_M PF01068.21 OAG44553.1 - 4.1e-58 196.4 0.8 6.2e-56 189.3 0.8 2.5 1 1 0 1 1 1 1 ATP dependent DNA ligase domain Ank_4 PF13637.6 OAG44553.1 - 1.1e-49 166.2 6.9 5.8e-07 29.9 0.0 11.7 7 4 3 11 11 11 10 Ankyrin repeats (many copies) DNA_ligase_A_N PF04675.14 OAG44553.1 - 2.3e-44 151.8 0.7 5.9e-44 150.4 0.2 2.0 2 0 0 2 2 2 1 DNA ligase N terminus Ank_3 PF13606.6 OAG44553.1 - 3.7e-32 106.7 12.4 0.14 12.8 0.0 15.8 16 0 0 16 16 16 7 Ankyrin repeat Ank PF00023.30 OAG44553.1 - 2e-31 107.1 6.4 0.027 14.9 0.0 15.7 16 1 0 16 16 16 8 Ankyrin repeat Ank_5 PF13857.6 OAG44553.1 - 1e-27 95.8 15.8 0.00084 19.6 0.0 11.0 7 4 5 12 12 12 10 Ankyrin repeats (many copies) DNA_ligase_A_C PF04679.15 OAG44553.1 - 2.5e-27 95.3 0.0 8.2e-27 93.7 0.0 2.0 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region Adeno_E1B_55K_N PF04623.12 OAG44553.1 - 0.073 13.8 0.0 0.42 11.3 0.0 2.4 2 0 0 2 2 2 0 Adenovirus E1B protein N-terminus Peptidase_S8 PF00082.22 OAG44555.1 - 5.5e-18 65.3 0.0 1e-17 64.4 0.0 1.4 1 0 0 1 1 1 1 Subtilase family Ank_2 PF12796.7 OAG44555.1 - 8.1e-07 29.5 0.0 0.059 14.0 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 OAG44555.1 - 3e-05 24.2 0.0 0.012 16.0 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 OAG44555.1 - 0.00038 20.7 0.1 0.15 12.7 0.0 4.2 4 0 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.6 OAG44555.1 - 0.001 19.6 0.1 0.066 13.8 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 OAG44555.1 - 0.065 13.6 0.1 47 4.5 0.0 3.8 2 2 1 3 3 3 0 Ankyrin repeats (many copies) DUF1759 PF03564.15 OAG44555.1 - 0.076 12.9 0.1 0.34 10.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1759) DEAD PF00270.29 OAG44557.1 - 3.1e-23 82.4 0.2 1.8e-22 80.0 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase RQC PF09382.10 OAG44557.1 - 9e-23 80.2 0.0 2.1e-22 79.0 0.0 1.7 1 0 0 1 1 1 1 RQC domain Helicase_C PF00271.31 OAG44557.1 - 1.5e-21 76.8 0.0 2.3e-17 63.3 0.0 3.0 2 0 0 2 2 2 2 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 OAG44557.1 - 3.3e-16 59.7 7.0 9.6e-16 58.3 7.0 1.9 1 0 0 1 1 1 1 RecQ zinc-binding ResIII PF04851.15 OAG44557.1 - 2.2e-05 24.5 0.0 5.4e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HRDC PF00570.23 OAG44557.1 - 0.0025 17.8 0.0 0.0067 16.4 0.0 1.7 1 0 0 1 1 1 1 HRDC domain Kelch_4 PF13418.6 OAG44558.1 - 8e-32 109.0 9.5 1.6e-08 34.4 0.0 6.3 5 1 0 5 5 5 5 Galactose oxidase, central domain DUF4110 PF13422.6 OAG44558.1 - 8.4e-29 99.5 4.2 8.4e-29 99.5 4.2 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4110) Kelch_3 PF13415.6 OAG44558.1 - 1.2e-28 98.8 12.8 5.6e-10 39.3 0.1 6.7 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_5 PF13854.6 OAG44558.1 - 8e-21 73.6 4.2 1.9e-06 27.7 0.0 6.2 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.6 OAG44558.1 - 2.3e-19 68.9 5.1 4.2e-06 26.8 0.0 6.0 5 1 1 6 6 6 4 Kelch motif Kelch_1 PF01344.25 OAG44558.1 - 8e-18 63.8 4.9 2.4e-09 36.6 0.0 5.0 4 1 0 4 4 4 4 Kelch motif Kelch_2 PF07646.15 OAG44558.1 - 2e-16 59.2 11.6 1.5e-06 28.0 0.0 6.1 6 1 0 6 6 6 4 Kelch motif GlutR_dimer PF00745.20 OAG44558.1 - 5 7.6 6.0 0.66 10.5 1.6 1.9 2 0 0 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain RRN3 PF05327.11 OAG44558.1 - 6.2 5.2 7.8 10 4.5 7.8 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 OAD_gamma PF04277.13 OAG44558.1 - 7.5 7.2 5.3 28 5.4 5.3 2.0 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Gpi16 PF04113.14 OAG44559.1 - 7.7e-235 780.6 0.0 9.5e-235 780.3 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component LUC7 PF03194.15 OAG44560.1 - 2.1e-70 237.2 1.0 2.6e-70 237.0 1.0 1.0 1 0 0 1 1 1 1 LUC7 N_terminus MCPsignal PF00015.21 OAG44560.1 - 0.039 13.8 0.0 0.065 13.0 0.0 1.4 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Spc7 PF08317.11 OAG44560.1 - 0.071 12.0 0.4 0.13 11.2 0.1 1.5 2 0 0 2 2 2 0 Spc7 kinetochore protein GRP PF07172.11 OAG44560.1 - 0.19 12.4 30.5 0.38 11.5 30.5 1.5 1 0 0 1 1 1 0 Glycine rich protein family CDC27 PF09507.10 OAG44561.1 - 6.5 6.0 17.4 0.11 11.9 10.2 1.6 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 OST3_OST6 PF04756.13 OAG44562.1 - 1.3e-101 339.9 0.0 1.7e-101 339.5 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin PF00085.20 OAG44562.1 - 0.0024 17.8 0.0 0.0042 17.0 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin HXXEE PF13787.6 OAG44562.1 - 2.2 9.1 7.0 0.32 11.8 1.5 2.1 1 1 1 2 2 2 0 Protein of unknown function with HXXEE motif MFS_1 PF07690.16 OAG44564.1 - 1.5e-36 126.0 22.3 2.2e-36 125.5 22.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily adh_short PF00106.25 OAG44566.1 - 6.1e-37 127.0 0.0 9.9e-18 64.3 0.1 2.0 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAG44566.1 - 5.3e-31 108.0 0.1 5.6e-16 58.8 0.2 2.2 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG44566.1 - 7.2e-05 22.8 0.0 0.00064 19.7 0.0 2.0 2 0 0 2 2 2 1 KR domain UDPG_MGDP_dh_N PF03721.14 OAG44566.1 - 0.00041 20.0 0.1 0.00074 19.1 0.1 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ADH_zinc_N PF00107.26 OAG44566.1 - 0.00049 20.1 0.2 0.0097 15.9 0.1 2.3 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 3HCDH_RFF PF18321.1 OAG44566.1 - 0.018 15.5 0.6 0.46 11.0 0.1 2.4 1 1 1 2 2 2 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain Epimerase PF01370.21 OAG44566.1 - 0.024 14.1 0.0 0.074 12.5 0.0 1.7 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 OAG44566.1 - 0.066 13.1 0.1 0.096 12.6 0.1 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Eno-Rase_NADH_b PF12242.8 OAG44566.1 - 0.09 12.6 0.1 0.19 11.5 0.1 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Shikimate_DH PF01488.20 OAG44566.1 - 0.15 12.1 0.0 0.34 11.0 0.0 1.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase KxDL PF10241.9 OAG44567.1 - 3.9e-05 23.8 0.9 3.9e-05 23.8 0.9 4.0 1 1 4 5 5 4 1 Uncharacterized conserved protein CLZ PF16526.5 OAG44567.1 - 0.0021 18.4 3.7 0.0021 18.4 3.7 5.1 2 1 3 5 5 5 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels KASH_CCD PF14662.6 OAG44567.1 - 0.003 17.4 43.0 0.016 15.1 29.2 2.4 1 1 1 2 2 2 2 Coiled-coil region of CCDC155 or KASH PulG PF11773.8 OAG44567.1 - 0.024 14.5 0.2 0.086 12.7 0.2 1.9 1 0 0 1 1 1 0 Type II secretory pathway pseudopilin WEMBL PF05701.11 OAG44567.1 - 0.04 12.6 38.7 0.073 11.8 38.7 1.4 1 0 0 1 1 1 0 Weak chloroplast movement under blue light CdiI_2 PF18593.1 OAG44567.1 - 0.38 11.4 0.1 0.38 11.4 0.1 2.8 3 1 1 4 4 3 0 CdiI immunity protein FlaC_arch PF05377.11 OAG44567.1 - 0.9 10.0 17.6 2 8.9 0.3 5.8 4 2 3 7 7 7 0 Flagella accessory protein C (FlaC) Phage_GP20 PF06810.11 OAG44567.1 - 1 9.1 32.9 0.044 13.6 7.4 3.8 1 1 2 3 3 3 0 Phage minor structural protein GP20 CENP-F_leu_zip PF10473.9 OAG44567.1 - 1.1 9.3 54.1 0.026 14.6 13.3 4.1 2 1 3 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF244 PF03112.14 OAG44567.1 - 1.7 8.5 4.6 1.4 8.7 0.7 2.4 1 1 2 3 3 3 0 Uncharacterized protein family (ORF7) DUF Snapin_Pallidin PF14712.6 OAG44567.1 - 5.5 7.5 26.9 0.96 9.9 2.1 4.1 1 1 2 3 3 3 0 Snapin/Pallidin TPR_MLP1_2 PF07926.12 OAG44567.1 - 5.9 7.0 51.3 6.7 6.8 24.1 4.8 1 1 3 4 4 4 0 TPR/MLP1/MLP2-like protein GAS PF13851.6 OAG44567.1 - 8.6 5.6 42.6 25 4.1 16.7 3.3 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding FtsJ PF01728.19 OAG44568.1 - 7.2e-55 185.8 0.0 8.9e-55 185.5 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.6 OAG44568.1 - 0.12 12.2 0.0 0.24 11.2 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain ATG7_N PF16420.5 OAG44569.1 - 2.2e-113 378.9 0.0 3e-113 378.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 OAG44569.1 - 1.3e-44 152.5 0.0 1.8e-44 151.9 0.0 1.2 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 OAG44569.1 - 0.14 12.2 0.0 0.37 10.8 0.0 1.6 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase dCMP_cyt_deam_1 PF00383.23 OAG44570.1 - 4.9e-27 93.8 2.7 7.2e-27 93.2 2.7 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 OAG44570.1 - 1.1e-11 44.6 0.3 1.7e-11 44.0 0.3 1.2 1 0 0 1 1 1 1 MafB19-like deaminase AAA_18 PF13238.6 OAG44570.1 - 0.0019 18.7 0.0 0.014 15.9 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 OAG44570.1 - 0.025 14.8 0.0 0.04 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Pex14_N PF04695.13 OAG44570.1 - 0.077 13.7 0.0 0.13 12.9 0.0 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Lambda_CIII PF02061.16 OAG44570.1 - 0.12 12.4 0.0 0.31 11.1 0.0 1.6 1 0 0 1 1 1 0 Lambda Phage CIII APOBEC4_like PF18774.1 OAG44570.1 - 0.16 11.9 0.0 0.28 11.1 0.0 1.3 1 0 0 1 1 1 0 APOBEC4-like -AID/APOBEC-deaminase CoaE PF01121.20 OAG44570.1 - 0.18 11.5 0.0 0.33 10.6 0.0 1.4 1 0 0 1 1 1 0 Dephospho-CoA kinase FTA2 PF13095.6 OAG44571.1 - 5e-35 121.1 0.0 8.7e-35 120.3 0.0 1.3 1 1 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 MFS_1 PF07690.16 OAG44574.1 - 1.4e-12 47.2 54.2 2.2e-11 43.3 52.5 3.0 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 OAG44574.1 - 2.7e-08 32.7 24.7 4.7e-08 31.9 24.7 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Med13_C PF06333.12 OAG44575.1 - 5.9e-84 282.1 0.6 5.9e-84 282.1 0.6 2.8 4 0 0 4 4 4 1 Mediator complex subunit 13 C-terminal domain Med13_N PF11597.8 OAG44575.1 - 1.7e-68 231.3 0.8 5.1e-68 229.8 0.8 1.9 1 0 0 1 1 1 1 Mediator complex subunit 13 N-terminal MID_MedPIWI PF18296.1 OAG44575.1 - 1.6e-08 34.7 12.1 2.4e-05 24.3 0.0 3.6 3 2 0 4 4 4 2 MID domain of medPIWI Chorion_2 PF03964.15 OAG44575.1 - 0.15 12.9 1.0 0.44 11.4 1.0 1.8 1 0 0 1 1 1 0 Chorion family 2 NUC153 PF08159.12 OAG44576.1 - 7e-13 48.1 0.9 1.8e-12 46.8 0.9 1.8 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.32 OAG44576.1 - 0.02 15.7 0.2 51 5.0 0.0 4.0 4 0 0 4 4 4 0 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG44576.1 - 0.07 13.4 0.1 0.51 10.7 0.0 2.4 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Isochorismatase PF00857.20 OAG44577.1 - 5.3e-47 160.2 0.0 6.5e-47 159.9 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family NUDE_C PF04880.13 OAG44578.1 - 2.5e-48 164.9 9.2 2.5e-48 164.9 9.2 4.3 2 2 4 6 6 6 1 NUDE protein, C-terminal conserved region ZapB PF06005.12 OAG44578.1 - 0.003 18.0 13.0 0.003 18.0 13.0 4.9 2 1 2 4 4 4 2 Cell division protein ZapB Atg14 PF10186.9 OAG44578.1 - 0.008 15.3 11.8 0.008 15.3 11.8 2.5 2 1 1 3 3 3 1 Vacuolar sorting 38 and autophagy-related subunit 14 Tropomyosin_1 PF12718.7 OAG44578.1 - 0.24 11.6 40.1 0.21 11.8 26.0 3.1 2 1 1 3 3 3 0 Tropomyosin like TPR_MLP1_2 PF07926.12 OAG44578.1 - 0.76 9.8 44.3 0.96 9.5 9.6 4.2 2 1 2 4 4 4 0 TPR/MLP1/MLP2-like protein Fez1 PF06818.15 OAG44578.1 - 1.6 9.1 34.0 3 8.2 20.9 2.7 2 1 1 3 3 3 0 Fez1 CCDC92 PF14916.6 OAG44578.1 - 1.9 8.3 8.3 0.91 9.3 0.8 3.4 2 1 1 3 3 3 0 Coiled-coil domain of unknown function YjbH PF06082.11 OAG44578.1 - 3.3 6.4 8.6 5 5.8 8.6 1.2 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH MAD PF05557.13 OAG44578.1 - 5.1 5.3 35.0 3 6.1 11.2 2.3 1 1 1 2 2 2 0 Mitotic checkpoint protein GST_N_3 PF13417.6 OAG44579.1 - 7.4e-11 42.3 0.0 1.4e-10 41.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 OAG44579.1 - 2.4e-10 40.6 0.0 4e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OAG44579.1 - 4.3e-06 26.9 0.0 7.6e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAG44579.1 - 0.00082 19.4 1.5 0.0033 17.4 0.3 2.4 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 OAG44579.1 - 0.0088 16.8 0.0 0.023 15.4 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C PF00043.25 OAG44579.1 - 0.13 12.5 0.0 0.62 10.3 0.0 2.0 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain DIOX_N PF14226.6 OAG44580.1 - 5.9e-18 65.7 0.0 1.2e-17 64.8 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OAG44580.1 - 9.3e-15 55.0 0.1 1.6e-14 54.2 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily adh_short PF00106.25 OAG44582.1 - 2.6e-25 89.0 0.3 3.2e-25 88.7 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG44582.1 - 5.9e-22 78.4 0.9 7.1e-22 78.1 0.9 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 OAG44582.1 - 1.1e-06 28.3 0.1 1.9e-06 27.5 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 OAG44582.1 - 2e-06 27.8 0.3 3.9e-06 26.9 0.3 1.5 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 OAG44582.1 - 8.8e-05 22.5 0.4 0.00013 21.9 0.4 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 OAG44582.1 - 0.0048 16.5 1.1 0.0078 15.8 1.1 1.2 1 0 0 1 1 1 1 NmrA-like family DUF1776 PF08643.10 OAG44582.1 - 0.17 11.2 0.0 1 8.7 0.0 1.9 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) zf-C2H2_4 PF13894.6 OAG44583.1 - 6.5e-06 26.5 25.8 0.0036 18.0 3.4 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-Di19 PF05605.12 OAG44583.1 - 3.1e-05 24.2 7.2 6.4e-05 23.2 7.2 1.6 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.26 OAG44583.1 - 5e-05 23.5 26.2 0.0026 18.1 4.4 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_8 PF15909.5 OAG44583.1 - 0.0018 18.5 1.0 0.0054 17.0 1.0 1.8 1 0 0 1 1 1 1 C2H2-type zinc ribbon zf-H2C2_2 PF13465.6 OAG44583.1 - 0.0045 17.4 5.0 0.0045 17.4 5.0 4.2 4 0 0 4 4 4 1 Zinc-finger double domain zf-H2C2_5 PF13909.6 OAG44583.1 - 0.039 13.7 18.4 0.23 11.3 2.0 4.1 3 1 0 3 3 3 0 C2H2-type zinc-finger domain Zn-ribbon_8 PF09723.10 OAG44583.1 - 6.6 6.9 14.5 1.6 8.9 8.8 2.4 1 1 1 2 2 2 0 Zinc ribbon domain Atx10homo_assoc PF09759.9 OAG44585.1 - 1.4e-24 86.0 0.3 9.3e-24 83.3 0.0 2.5 3 0 0 3 3 3 1 Spinocerebellar ataxia type 10 protein domain Mito_carr PF00153.27 OAG44586.1 - 3.8e-54 180.6 3.2 6.2e-18 64.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Antimicrobial20 PF08256.11 OAG44586.1 - 0.82 10.4 0.1 0.82 10.4 0.1 3.1 3 0 0 3 3 3 0 Aurein-like antibiotic peptide zf-C3HC PF07967.13 OAG44587.1 - 2.3e-35 121.5 1.2 9.9e-29 100.0 0.0 3.4 2 1 0 2 2 2 2 C3HC zinc finger-like Rsm1 PF08600.10 OAG44587.1 - 2e-16 59.9 0.8 1.5e-15 57.1 0.1 2.5 3 0 0 3 3 3 1 Rsm1-like BIR PF00653.21 OAG44587.1 - 2.5e-05 24.9 0.4 0.035 14.8 0.1 2.5 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain zf-TFIIB PF13453.6 OAG44587.1 - 0.0046 16.3 1.0 0.011 15.0 0.3 2.0 2 0 0 2 2 2 1 Transcription factor zinc-finger RNF220 PF15926.5 OAG44587.1 - 0.53 9.9 3.3 0.6 9.7 0.2 2.5 2 1 0 2 2 2 0 E3 ubiquitin-protein ligase RNF220 zf-RING_4 PF14570.6 OAG44589.1 - 1.7e-17 62.9 13.3 3.1e-17 62.1 13.3 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 OAG44589.1 - 2.4e-07 30.5 7.7 4.1e-07 29.8 7.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.22 OAG44589.1 - 0.00021 21.0 0.0 0.00049 19.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RING_2 PF13639.6 OAG44589.1 - 0.00051 20.3 11.2 0.001 19.4 11.2 1.5 1 0 0 1 1 1 1 Ring finger domain Rtf2 PF04641.12 OAG44589.1 - 0.00077 18.9 3.9 0.00077 18.9 3.9 5.5 5 1 1 6 6 4 1 Rtf2 RING-finger Prok-RING_4 PF14447.6 OAG44589.1 - 0.01 15.7 9.6 0.21 11.5 10.1 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 FYVE PF01363.21 OAG44589.1 - 0.4 10.9 3.6 1 9.6 3.6 1.7 1 0 0 1 1 1 0 FYVE zinc finger zf-RING_5 PF14634.6 OAG44589.1 - 0.57 10.2 11.7 1 9.4 11.7 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.25 OAG44589.1 - 0.95 9.4 12.1 1.7 8.5 12.1 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Baculo_IE-1 PF05290.11 OAG44589.1 - 1.7 8.6 6.7 3.4 7.6 6.7 1.4 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) DZR PF12773.7 OAG44589.1 - 4.9 7.3 10.1 24 5.1 10.3 2.0 1 1 0 1 1 1 0 Double zinc ribbon zf-C3HC4_2 PF13923.6 OAG44589.1 - 9.5 6.2 11.2 18 5.3 11.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Complex1_30kDa PF00329.19 OAG44590.1 - 2.8e-45 153.9 0.0 3.9e-45 153.4 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 2-Hacid_dh_C PF02826.19 OAG44591.1 - 1.4e-54 184.2 0.0 2e-54 183.6 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 OAG44591.1 - 2.6e-35 121.0 0.1 5.2e-35 120.0 0.1 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain XdhC_C PF13478.6 OAG44591.1 - 0.017 15.6 0.0 0.037 14.5 0.0 1.6 1 0 0 1 1 1 0 XdhC Rossmann domain IlvN PF07991.12 OAG44591.1 - 0.029 14.0 0.0 0.055 13.0 0.0 1.5 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain AdoHcyase_NAD PF00670.21 OAG44591.1 - 0.062 13.4 0.2 0.15 12.1 0.2 1.6 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Fe-ADH PF00465.19 OAG44592.1 - 2.4e-102 342.5 0.0 2.9e-102 342.2 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 OAG44592.1 - 2.7e-14 53.5 0.0 1.1e-10 41.7 0.0 2.3 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Peripla_BP_6 PF13458.6 OAG44592.1 - 0.015 15.0 0.0 0.025 14.2 0.0 1.3 1 0 0 1 1 1 0 Periplasmic binding protein Glyoxalase PF00903.25 OAG44593.1 - 1.1e-40 138.8 0.0 4.4e-19 69.0 0.0 2.1 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 OAG44593.1 - 4.4e-15 55.9 0.0 1.2e-06 28.7 0.0 3.7 2 2 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 OAG44593.1 - 5.3e-06 27.2 0.0 0.077 13.8 0.0 2.8 2 2 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_3 PF13468.6 OAG44593.1 - 5.7e-06 26.6 0.0 0.099 12.8 0.0 3.3 1 1 1 2 2 2 2 Glyoxalase-like domain Glyoxalase_2 PF12681.7 OAG44593.1 - 0.00074 19.4 0.9 1.2 9.1 0.0 3.8 4 0 0 4 4 4 1 Glyoxalase-like domain MoaF PF10703.9 OAG44593.1 - 0.00077 19.4 0.1 0.049 13.6 0.0 2.5 2 0 0 2 2 2 1 MoaF N-terminal domain DUF1338 PF07063.13 OAG44593.1 - 0.0015 17.8 0.0 0.3 10.2 0.0 3.3 4 0 0 4 4 4 1 Domain of unknown function (DUF1338) HTH_54 PF18607.1 OAG44593.1 - 0.01 15.9 0.0 2.1 8.5 0.0 2.4 2 0 0 2 2 2 0 ParA helix turn helix domain NIL PF09383.10 OAG44593.1 - 0.043 13.7 0.0 5.9 6.8 0.0 2.3 2 0 0 2 2 2 0 NIL domain CppA_N PF14506.6 OAG44593.1 - 0.16 12.0 0.1 4.4 7.4 0.0 2.3 2 0 0 2 2 2 0 CppA N-terminal ILVD_EDD PF00920.21 OAG44594.1 - 8.1e-155 516.3 0.1 9.2e-155 516.2 0.1 1.0 1 0 0 1 1 1 1 Dehydratase family FAD_binding_4 PF01565.23 OAG44596.1 - 1.2e-26 93.1 1.9 2.3e-26 92.2 1.9 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 OAG44596.1 - 0.00019 21.5 0.6 0.00046 20.2 0.6 1.6 1 0 0 1 1 1 1 Berberine and berberine like MCM_bind PF09739.9 OAG44596.1 - 0.19 10.1 0.0 3.4 6.0 0.0 2.0 2 0 0 2 2 2 0 Mini-chromosome maintenance replisome factor DUF508 PF04370.12 OAG44596.1 - 0.22 11.2 0.5 1.2 8.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF508) DUF1932 PF09130.11 OAG44597.1 - 3.8e-26 90.9 0.0 9.8e-26 89.5 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1932) F420_oxidored PF03807.17 OAG44597.1 - 0.003 18.1 0.1 0.016 15.8 0.1 2.2 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 OAG44597.1 - 0.009 16.2 0.4 0.074 13.2 0.4 2.3 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase RINGv PF12906.7 OAG44599.1 - 6.7e-16 58.2 7.9 1.2e-15 57.4 7.9 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 OAG44599.1 - 0.0025 18.1 7.3 0.0045 17.3 7.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-ANAPC11 PF12861.7 OAG44599.1 - 0.23 11.5 2.6 0.54 10.4 2.6 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Baculo_PEP_C PF04513.12 OAG44599.1 - 0.55 10.3 3.5 23 5.0 0.0 4.3 5 0 0 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus TPR_1 PF00515.28 OAG44600.1 - 1.3e-38 129.3 13.6 4.8e-08 32.5 0.2 8.9 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_2 PF07719.17 OAG44600.1 - 2.5e-35 117.7 20.0 1e-06 28.4 0.1 10.0 10 0 0 10 10 10 7 Tetratricopeptide repeat ANAPC3 PF12895.7 OAG44600.1 - 5.5e-30 103.4 17.2 2.5e-20 72.5 0.5 4.7 4 0 0 4 4 4 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 OAG44600.1 - 4.1e-23 79.6 6.6 0.0024 17.9 0.0 8.7 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_11 PF13414.6 OAG44600.1 - 5.5e-20 70.8 8.1 6.3e-07 29.0 3.0 9.0 7 3 3 10 10 10 3 TPR repeat TPR_16 PF13432.6 OAG44600.1 - 9.7e-20 70.9 18.8 2.9e-08 34.2 0.6 7.4 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.6 OAG44600.1 - 1.3e-18 66.1 24.3 0.038 14.8 0.0 10.7 7 1 5 12 12 11 7 Tetratricopeptide repeat TPR_19 PF14559.6 OAG44600.1 - 3.6e-18 65.8 17.3 1.4e-05 25.5 0.0 7.2 5 3 2 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.6 OAG44600.1 - 1.4e-16 59.6 11.4 0.039 14.3 0.0 9.0 10 0 0 10 10 8 4 Tetratricopeptide repeat TPR_12 PF13424.6 OAG44600.1 - 1.1e-13 51.2 11.2 0.003 17.8 0.0 6.6 4 1 2 6 6 6 5 Tetratricopeptide repeat TPR_9 PF13371.6 OAG44600.1 - 1.3e-11 44.5 9.2 0.0089 16.2 0.2 6.0 6 1 1 7 7 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 OAG44600.1 - 1.7e-08 33.9 5.8 0.1 12.7 0.0 6.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.6 OAG44600.1 - 1e-07 32.1 15.8 1.5 9.6 0.0 9.1 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_15 PF13429.6 OAG44600.1 - 0.00029 20.2 4.6 0.91 8.7 0.0 4.8 1 1 4 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 OAG44600.1 - 0.00067 19.4 4.4 3.3 7.7 0.1 5.2 6 0 0 6 6 6 2 Tetratricopeptide repeat YfiO PF13525.6 OAG44600.1 - 0.044 13.5 2.8 2.1 8.0 0.3 2.5 2 0 0 2 2 2 0 Outer membrane lipoprotein TMEM208_SND2 PF05620.11 OAG44601.1 - 8e-53 178.7 0.1 9e-53 178.5 0.1 1.0 1 0 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 Mito_carr PF00153.27 OAG44602.1 - 1.1e-42 143.9 0.1 9.7e-14 51.1 0.0 3.5 3 0 0 3 3 3 3 Mitochondrial carrier protein PHD PF00628.29 OAG44602.1 - 4.7e-09 36.0 7.1 4.7e-09 36.0 7.1 2.1 2 0 0 2 2 2 1 PHD-finger JmjC PF02373.22 OAG44602.1 - 4.9e-08 33.4 0.0 2.5e-07 31.1 0.0 2.2 1 1 0 1 1 1 1 JmjC domain, hydroxylase JHD PF17811.1 OAG44602.1 - 2e-07 31.5 0.2 5e-07 30.2 0.2 1.7 1 0 0 1 1 1 1 Jumonji helical domain Cupin_8 PF13621.6 OAG44602.1 - 1.1e-05 25.3 0.0 5.9e-05 22.9 0.0 2.1 1 1 0 1 1 1 1 Cupin-like domain PHD_2 PF13831.6 OAG44602.1 - 0.0038 16.8 3.5 0.009 15.5 3.5 1.6 1 0 0 1 1 1 1 PHD-finger PHD_Oberon PF07227.11 OAG44602.1 - 0.0041 17.0 2.0 0.0097 15.8 2.0 1.5 1 0 0 1 1 1 1 PHD - plant homeodomain finger protein zf-RING_9 PF13901.6 OAG44602.1 - 1.3 9.0 6.0 3.8 7.4 6.0 1.7 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon PHD_4 PF16866.5 OAG44602.1 - 3.6 7.8 6.4 18 5.5 6.2 2.2 2 0 0 2 2 2 0 PHD-finger zf-HC5HC2H_2 PF13832.6 OAG44602.1 - 3.6 7.8 5.7 0.67 10.1 1.6 1.9 2 0 0 2 2 2 0 PHD-zinc-finger like domain C1_1 PF00130.22 OAG44602.1 - 7.2 6.6 9.3 0.12 12.2 1.7 2.0 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) RRM_1 PF00076.22 OAG44603.1 - 1.4e-17 63.3 0.1 1.9e-17 62.8 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OAG44603.1 - 0.00013 21.6 0.1 0.00014 21.4 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AIRC PF00731.20 OAG44604.1 - 8.4e-58 194.2 1.1 1.5e-57 193.4 1.1 1.4 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.22 OAG44604.1 - 1.1e-46 158.5 0.0 1.7e-46 158.0 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain PurK_C PF17769.1 OAG44604.1 - 4.2e-19 68.0 0.0 9.5e-19 66.8 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain AlaDh_PNT_C PF01262.21 OAG44604.1 - 0.019 14.3 0.1 0.051 12.9 0.1 1.7 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 OAG44604.1 - 0.04 14.2 0.0 0.098 12.9 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain XdhC_C PF13478.6 OAG44604.1 - 0.061 13.8 0.2 0.3 11.6 0.0 2.3 3 0 0 3 3 3 0 XdhC Rossmann domain Dala_Dala_lig_C PF07478.13 OAG44604.1 - 0.063 12.8 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus Pyr_redox PF00070.27 OAG44604.1 - 0.083 13.5 0.3 20 5.9 0.1 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TFIIIC_sub6 PF10419.9 OAG44605.1 - 3.1e-21 75.0 0.0 5.3e-21 74.3 0.0 1.4 1 0 0 1 1 1 1 TFIIIC subunit triple barrel domain DUF4107 PF13389.6 OAG44605.1 - 0.0046 17.1 0.2 0.0072 16.5 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Vps62 PF06101.11 OAG44606.1 - 2.9e-11 42.4 0.9 5.7e-11 41.4 0.9 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 62 DUF1302 PF06980.11 OAG44606.1 - 0.045 12.4 0.1 0.066 11.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1302) STIMATE PF12400.8 OAG44607.1 - 3.7e-40 137.4 2.1 4.7e-40 137.0 1.5 1.4 2 0 0 2 2 2 1 STIMATE family ABC2_membrane_3 PF12698.7 OAG44607.1 - 3.6 6.6 8.0 0.26 10.3 1.9 1.9 1 1 0 2 2 2 0 ABC-2 family transporter protein ELFV_dehydrog PF00208.21 OAG44608.1 - 3.8e-67 226.6 0.0 7.1e-67 225.7 0.0 1.5 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 OAG44608.1 - 2.9e-18 64.9 0.1 1.4e-12 46.1 0.0 2.1 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.18 OAG44608.1 - 0.03 14.2 0.0 0.11 12.4 0.0 1.9 2 0 0 2 2 2 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain DUF2011 PF09428.10 OAG44609.1 - 2.6e-21 75.6 0.2 2.6e-21 75.6 0.2 2.1 2 1 0 2 2 2 1 Fungal protein of unknown function (DUF2011) GRP PF07172.11 OAG44609.1 - 0.03 15.0 4.3 0.03 15.0 4.3 2.0 2 0 0 2 2 2 0 Glycine rich protein family DUF1148 PF06618.11 OAG44609.1 - 0.18 12.0 0.0 0.31 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1148) Mucin PF01456.17 OAG44609.1 - 4.6 7.2 18.4 2.5 8.1 8.0 2.6 2 0 0 2 2 2 0 Mucin-like glycoprotein Ferlin_C PF16165.5 OAG44609.1 - 5.8 6.9 7.6 14 5.6 7.6 1.5 1 0 0 1 1 1 0 Ferlin C-terminus PNP_UDP_1 PF01048.20 OAG44610.1 - 1.4e-36 125.9 0.1 1.8e-36 125.6 0.1 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Rhodanese PF00581.20 OAG44611.1 - 1.6e-11 44.7 0.0 3.6e-11 43.5 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain ARID PF01388.21 OAG44613.1 - 3.4e-19 69.3 0.0 8.6e-19 68.0 0.0 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain Pro_CA PF00484.19 OAG44615.1 - 1.7e-11 44.6 0.0 2.5e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 Carbonic anhydrase adh_short PF00106.25 OAG44616.1 - 1.8e-24 86.3 0.1 2.6e-24 85.8 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG44616.1 - 1.5e-22 80.3 0.0 1.9e-22 80.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 OAG44616.1 - 2.1e-05 24.1 0.2 0.0029 17.1 0.1 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family KR PF08659.10 OAG44616.1 - 0.00055 19.9 0.0 0.00091 19.2 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 OAG44616.1 - 0.011 15.6 0.3 0.038 13.9 0.3 1.8 1 1 0 1 1 1 0 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 OAG44616.1 - 0.017 14.6 0.3 2.4 7.4 0.1 2.1 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase FtsJ PF01728.19 OAG44616.1 - 0.069 13.3 0.0 0.078 13.1 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase adh_short PF00106.25 OAG44617.1 - 9.2e-26 90.5 0.7 2.4e-15 56.5 0.1 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAG44617.1 - 3.1e-16 59.7 0.5 3e-10 40.1 0.1 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 OAG44617.1 - 5.2e-05 22.8 0.1 0.13 11.7 0.0 2.3 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family KR PF08659.10 OAG44617.1 - 0.0025 17.8 0.0 0.0046 16.9 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 OAG44617.1 - 0.0058 16.5 0.2 0.11 12.3 0.1 2.1 2 0 0 2 2 2 1 NAD(P)H-binding TrkA_N PF02254.18 OAG44617.1 - 0.011 15.9 0.1 0.023 15.0 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain GDP_Man_Dehyd PF16363.5 OAG44617.1 - 0.012 15.0 0.0 2.8 7.3 0.0 2.1 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase ADH_zinc_N PF00107.26 OAG44617.1 - 0.14 12.2 0.1 0.39 10.7 0.0 1.8 2 0 0 2 2 2 0 Zinc-binding dehydrogenase FAD_binding_3 PF01494.19 OAG44618.1 - 4.3e-85 286.0 0.0 5.2e-85 285.8 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 OAG44618.1 - 0.057 12.6 0.1 0.15 11.3 0.1 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Aldo_ket_red PF00248.21 OAG44619.1 - 1.2e-44 152.7 0.0 1.4e-44 152.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family EHN PF06441.12 OAG44620.1 - 1.6e-37 128.2 0.6 1.2e-35 122.1 0.0 2.3 2 0 0 2 2 2 2 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 OAG44620.1 - 5.4e-06 26.2 0.0 1.8e-05 24.5 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold CG-1 PF03859.16 OAG44620.1 - 0.22 11.3 0.5 1.4 8.7 0.0 2.2 2 0 0 2 2 2 0 CG-1 domain ABM PF03992.16 OAG44621.1 - 0.0066 16.5 0.4 0.015 15.4 0.4 1.5 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase ORC6 PF05460.13 OAG44621.1 - 0.018 14.3 0.4 0.024 13.9 0.4 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) adh_short PF00106.25 OAG44622.1 - 2.2e-40 138.2 0.1 2.8e-40 137.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG44622.1 - 2.1e-29 102.8 0.0 7e-29 101.0 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG44622.1 - 4.8e-12 46.2 0.0 6.9e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OAG44622.1 - 9.6e-09 34.8 0.0 1.2e-08 34.4 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 OAG44622.1 - 4e-07 29.8 0.1 1.2e-06 28.2 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OAG44622.1 - 2.1e-05 23.7 0.1 2.9e-05 23.2 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Ldh_1_N PF00056.23 OAG44622.1 - 0.0017 18.5 0.1 0.0034 17.5 0.1 1.6 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 OAG44622.1 - 0.0026 17.2 0.0 0.0037 16.7 0.0 1.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase ThiF PF00899.21 OAG44622.1 - 0.035 13.4 0.1 0.082 12.2 0.1 1.6 1 0 0 1 1 1 0 ThiF family Methyltransf_25 PF13649.6 OAG44622.1 - 0.038 14.7 0.0 0.12 13.1 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain CENP-B_dimeris PF09026.10 OAG44623.1 - 0.0005 20.4 8.6 0.001 19.4 8.6 1.5 1 0 0 1 1 1 1 Centromere protein B dimerisation domain Herpes_gE PF02480.16 OAG44623.1 - 0.036 12.8 0.0 0.036 12.8 0.0 2.1 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E DUF3481 PF11980.8 OAG44623.1 - 0.14 11.8 0.1 0.29 10.9 0.1 1.4 1 0 0 1 1 1 0 C-terminal domain of neuropilin glycoprotein Nop14 PF04147.12 OAG44623.1 - 0.42 8.8 4.6 0.56 8.4 4.6 1.1 1 0 0 1 1 1 0 Nop14-like family Alpha_GJ PF03229.13 OAG44623.1 - 1 10.0 14.9 0.1 13.2 9.9 2.0 2 0 0 2 2 2 0 Alphavirus glycoprotein J NOA36 PF06524.12 OAG44623.1 - 3 7.1 8.2 4.3 6.6 8.2 1.1 1 0 0 1 1 1 0 NOA36 protein Cwf_Cwc_15 PF04889.12 OAG44623.1 - 7.2 6.3 11.2 12 5.5 11.2 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Ferric_reduct PF01794.19 OAG44624.1 - 3.1e-20 72.5 6.7 3.1e-20 72.5 6.7 2.3 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 OAG44624.1 - 3.4e-16 59.8 0.4 1.5e-09 38.1 0.1 2.3 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 OAG44624.1 - 1.3e-08 34.9 0.0 8.3e-05 22.6 0.0 2.4 2 0 0 2 2 2 2 FAD-binding domain Beta-lactamase PF00144.24 OAG44626.1 - 4.7e-46 157.6 0.1 8.3e-46 156.7 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase EthD PF07110.11 OAG44627.1 - 1.9e-19 70.6 0.1 2.6e-19 70.2 0.1 1.2 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 OAG44627.1 - 2.3e-06 28.0 0.0 3.3e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Methylmuconolactone methyl-isomerase Speriolin_C PF15059.6 OAG44627.1 - 0.0045 17.1 0.0 0.0057 16.8 0.0 1.2 1 0 0 1 1 1 1 Speriolin C-terminus GST_N PF02798.20 OAG44628.1 - 1e-08 35.4 0.0 1.5e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OAG44628.1 - 1.4e-07 31.7 0.0 2.5e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 OAG44628.1 - 2.6e-07 31.0 0.0 4.5e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OAG44628.1 - 0.0032 17.7 0.0 0.0049 17.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OAG44628.1 - 0.066 13.2 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Oxidored_FMN PF00724.20 OAG44629.1 - 1.9e-58 198.4 0.0 2.3e-58 198.1 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family SnoaL_4 PF13577.6 OAG44630.1 - 2.9e-11 43.6 5.1 3.7e-11 43.2 5.1 1.1 1 0 0 1 1 1 1 SnoaL-like domain Lzipper-MIP1 PF14389.6 OAG44630.1 - 0.062 13.6 0.3 0.095 13.0 0.3 1.3 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 ISP1_C PF18161.1 OAG44630.1 - 0.12 12.3 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 ISP1 C-terminal Ribosomal_S15 PF00312.22 OAG44630.1 - 0.14 12.4 0.4 0.27 11.5 0.4 1.5 1 0 0 1 1 1 0 Ribosomal protein S15 SnoaL_2 PF12680.7 OAG44630.1 - 0.17 12.6 3.5 0.52 11.0 3.0 2.2 1 1 1 2 2 2 0 SnoaL-like domain ABC_tran_CTD PF16326.5 OAG44630.1 - 0.18 12.1 3.0 0.3 11.3 3.0 1.3 1 0 0 1 1 1 0 ABC transporter C-terminal domain Sugar_tr PF00083.24 OAG44631.1 - 2.6e-84 283.7 28.3 2.9e-84 283.5 28.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG44631.1 - 7.1e-32 110.7 40.3 2.7e-27 95.7 18.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Lactamase_B PF00753.27 OAG44632.1 - 9.7e-11 42.0 0.3 1.5e-10 41.4 0.3 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OAG44632.1 - 0.00046 19.8 0.0 0.0019 17.8 0.0 1.9 2 0 0 2 2 2 1 Beta-lactamase superfamily domain TauD PF02668.16 OAG44633.1 - 4.9e-57 193.7 2.3 5.7e-57 193.5 2.3 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family TPP_enzyme_N PF02776.18 OAG44634.1 - 3.1e-34 118.0 0.2 3.3e-31 108.2 0.1 2.7 2 1 0 2 2 2 2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 OAG44634.1 - 1.8e-18 66.8 0.0 4.3e-18 65.5 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 OAG44634.1 - 3.6e-05 23.5 0.0 0.00051 19.8 0.0 2.4 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain MFS_1 PF07690.16 OAG44635.1 - 2.2e-39 135.4 25.3 2.2e-39 135.4 25.3 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 OAG44635.1 - 0.0053 15.1 7.9 0.077 11.3 5.2 2.5 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family AMP-binding PF00501.28 OAG44637.1 - 3.2e-10 39.2 0.1 3.9e-10 38.9 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme MFS_1 PF07690.16 OAG44638.1 - 2.9e-23 82.4 30.9 2.9e-23 82.4 30.9 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG44638.1 - 4.2e-14 52.3 22.3 1.4e-11 44.0 21.9 2.3 1 1 0 1 1 1 1 Sugar (and other) transporter UPF0182 PF03699.13 OAG44638.1 - 0.0039 15.4 3.1 0.0054 14.9 3.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0182) Serpentine_r_xa PF03383.15 OAG44638.1 - 0.033 14.1 0.1 1.1 9.2 0.0 2.4 2 0 0 2 2 2 0 Caenorhabditis serpentine receptor-like protein, class xa FMO-like PF00743.19 OAG44639.1 - 7.3e-18 64.3 0.5 6.5e-11 41.3 0.0 3.1 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OAG44639.1 - 9.7e-09 34.9 0.0 1.2e-06 28.0 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAG44639.1 - 2.5e-08 33.5 0.0 7.4e-06 25.4 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG44639.1 - 1.8e-07 31.3 0.0 8.4e-07 29.1 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 OAG44639.1 - 4.3e-07 29.4 0.0 3e-05 23.4 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 OAG44639.1 - 0.00092 19.7 0.0 0.53 10.9 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAG44639.1 - 0.016 14.5 0.0 1.2 8.3 0.0 2.3 2 0 0 2 2 2 0 Thi4 family DAO PF01266.24 OAG44639.1 - 0.029 14.0 0.0 7.9 6.0 0.0 2.9 3 0 0 3 3 3 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 OAG44639.1 - 0.055 13.5 0.7 2.9 7.9 0.0 2.7 3 0 0 3 3 3 0 FAD-NAD(P)-binding Aldedh PF00171.22 OAG44640.1 - 6.8e-152 506.2 0.0 7.8e-152 506.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family ADH_zinc_N PF00107.26 OAG44641.1 - 4e-22 78.6 0.4 6.4e-22 77.9 0.4 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG44641.1 - 5.9e-19 68.0 3.8 8.5e-11 41.7 0.6 2.7 3 0 0 3 3 3 2 Alcohol dehydrogenase GroES-like domain 2-Hacid_dh_C PF02826.19 OAG44641.1 - 0.00016 21.1 0.0 0.00027 20.3 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.6 OAG44641.1 - 0.00032 21.8 0.0 0.00081 20.4 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 OAG44641.1 - 0.002 17.5 0.6 0.0032 16.8 0.6 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_2 PF03446.15 OAG44641.1 - 0.072 13.3 0.1 0.13 12.4 0.1 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Peptidase_S15 PF02129.18 OAG44642.1 - 1.8e-33 116.3 4.7 4.5e-31 108.4 1.1 2.9 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 OAG44642.1 - 1.6e-30 106.8 0.0 2.1e-30 106.3 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Fungal_trans PF04082.18 OAG44643.1 - 1.4e-27 96.4 4.7 2.2e-27 95.8 4.7 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAD_binding_4 PF01565.23 OAG44644.1 - 1.1e-25 90.0 0.0 1.8e-25 89.3 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.19 OAG44644.1 - 1.1e-12 48.1 0.0 1.7e-12 47.5 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain SKICH PF17751.1 OAG44644.1 - 0.081 13.5 0.0 0.23 12.0 0.0 1.7 2 0 0 2 2 2 0 SKICH domain LisH PF08513.11 OAG44644.1 - 0.16 12.0 0.2 0.39 10.7 0.2 1.6 1 0 0 1 1 1 0 LisH FAD_binding_3 PF01494.19 OAG44645.1 - 8e-18 64.8 0.1 2.1e-16 60.1 0.1 2.2 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAG44645.1 - 4.4e-05 23.2 0.4 0.028 14.0 0.1 2.5 1 1 1 2 2 2 2 FAD dependent oxidoreductase SE PF08491.10 OAG44645.1 - 0.0011 18.1 0.0 0.0067 15.5 0.0 1.9 2 0 0 2 2 2 1 Squalene epoxidase Lycopene_cycl PF05834.12 OAG44645.1 - 0.0018 17.4 0.1 0.011 14.9 0.0 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 OAG44645.1 - 0.023 14.0 0.0 0.072 12.3 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG44645.1 - 0.12 12.6 0.0 0.28 11.4 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 OAG44645.1 - 0.16 11.2 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 Thi4 family Fungal_trans PF04082.18 OAG44646.1 - 1.7e-06 27.3 0.1 3.6e-06 26.2 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG44646.1 - 0.027 14.6 2.5 0.058 13.5 2.5 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Asp PF00026.23 OAG44648.1 - 2.5e-39 135.6 0.0 6.9e-39 134.1 0.0 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 OAG44648.1 - 7.9e-06 26.4 0.8 0.0082 16.8 0.3 3.5 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 OAG44648.1 - 3.3e-05 24.3 0.1 0.037 14.6 0.0 3.4 3 0 0 3 3 3 2 gag-polyprotein putative aspartyl protease TAXi_N PF14543.6 OAG44648.1 - 0.0003 21.1 0.8 0.0041 17.4 0.2 2.7 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Abhydrolase_3 PF07859.13 OAG44649.1 - 2.2e-41 142.0 0.0 7.8e-31 107.6 0.0 3.2 3 0 0 3 3 3 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 OAG44649.1 - 1.7e-14 53.5 0.0 4.3e-14 52.2 0.0 1.5 2 0 0 2 2 2 1 Steryl acetyl hydrolase COesterase PF00135.28 OAG44649.1 - 0.013 14.4 0.3 0.19 10.6 0.3 2.2 1 1 0 1 1 1 0 Carboxylesterase family SNF2_N PF00176.23 OAG44651.1 - 3.2e-67 226.7 0.2 4.9e-67 226.1 0.2 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 OAG44651.1 - 3e-06 27.3 0.0 5.4e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 OAG44651.1 - 1.4e-05 25.4 0.0 3.7e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 OAG44651.1 - 7e-05 22.7 0.0 0.00017 21.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ParA PF10609.9 OAG44652.1 - 8.4e-87 290.7 0.1 1.7e-86 289.7 0.1 1.5 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 OAG44652.1 - 2e-11 44.0 0.0 1e-10 41.8 0.0 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 OAG44652.1 - 4.1e-07 30.1 0.0 8.7e-07 29.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain MipZ PF09140.11 OAG44652.1 - 5.5e-05 22.6 0.1 0.0001 21.7 0.1 1.4 1 0 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 OAG44652.1 - 0.00058 19.1 1.3 0.0062 15.8 0.1 2.4 2 1 1 3 3 3 1 Anion-transporting ATPase AAA_25 PF13481.6 OAG44652.1 - 0.0055 16.3 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain CLP1_P PF16575.5 OAG44652.1 - 0.057 13.2 0.0 0.099 12.4 0.0 1.3 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop PhnA_Zn_Ribbon PF08274.12 OAG44652.1 - 0.14 12.2 0.3 0.27 11.2 0.3 1.4 1 0 0 1 1 1 0 PhnA Zinc-Ribbon BUD22 PF09073.10 OAG44653.1 - 6.4e-87 292.7 14.8 7.8e-87 292.4 14.8 1.1 1 0 0 1 1 1 1 BUD22 DUF4199 PF13858.6 OAG44654.1 - 0.19 12.1 4.6 5.1 7.5 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) DUF2834 PF11196.8 OAG44654.1 - 4.3 7.8 11.5 3.9 7.9 1.6 3.9 3 1 1 4 4 4 0 Protein of unknown function (DUF2834) Asp PF00026.23 OAG44655.1 - 1e-63 215.7 2.0 1.6e-63 215.0 2.0 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OAG44655.1 - 8.4e-14 52.2 1.5 9e-09 35.8 0.1 2.9 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.6 OAG44655.1 - 0.014 16.0 0.1 12 6.5 0.0 2.9 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 OAG44655.1 - 0.042 14.5 0.4 22 5.7 0.0 3.2 3 0 0 3 3 3 0 Aspartyl protease TAXi_C PF14541.6 OAG44655.1 - 0.072 12.9 0.1 2.6 7.8 0.1 2.6 2 1 0 2 2 2 0 Xylanase inhibitor C-terminal RCC1 PF00415.18 OAG44656.1 - 1.6e-20 73.5 0.2 2.3e-05 24.9 0.0 6.0 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 OAG44656.1 - 6.5e-13 48.9 0.2 9.7e-08 32.2 0.0 2.6 2 0 0 2 2 2 2 BTB/POZ domain Ank_4 PF13637.6 OAG44656.1 - 8e-11 42.2 0.1 5.9e-10 39.5 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) RCC1_2 PF13540.6 OAG44656.1 - 5.5e-09 35.6 10.1 6.6e-08 32.1 1.0 4.6 5 0 0 5 5 5 1 Regulator of chromosome condensation (RCC1) repeat Ank_2 PF12796.7 OAG44656.1 - 7.6e-09 36.0 0.1 2.6e-08 34.3 0.1 1.9 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OAG44656.1 - 2.1e-06 27.6 0.1 0.15 12.7 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 OAG44656.1 - 0.0015 18.9 0.1 0.1 13.1 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 OAG44656.1 - 0.0081 16.5 0.1 0.29 11.5 0.0 2.9 1 1 1 2 2 2 1 Ankyrin repeats (many copies) ATG13 PF10033.9 OAG44657.1 - 2.6e-68 230.3 0.0 4.4e-68 229.5 0.0 1.4 1 0 0 1 1 1 1 Autophagy-related protein 13 Med22 PF06179.12 OAG44659.1 - 2.2e-10 40.7 0.1 3.3e-10 40.1 0.1 1.4 1 1 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex DBR1 PF05011.13 OAG44659.1 - 0.048 14.1 0.0 0.061 13.8 0.0 1.3 1 0 0 1 1 1 0 Lariat debranching enzyme, C-terminal domain DUF3138 PF11336.8 OAG44659.1 - 1.2 7.7 4.1 1.5 7.3 4.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DHFR_1 PF00186.19 OAG44660.1 - 3.6e-17 62.5 0.0 9.9e-08 31.8 0.0 4.1 4 0 0 4 4 4 3 Dihydrofolate reductase PAS_4 PF08448.10 OAG44660.1 - 0.38 11.0 1.6 5.6 7.3 0.0 3.3 3 1 1 4 4 4 0 PAS fold FAM176 PF14851.6 OAG44660.1 - 1.8 8.2 6.3 18 5.0 0.3 2.9 3 0 0 3 3 3 0 FAM176 family CsbD PF05532.12 OAG44661.1 - 0.019 14.9 0.9 0.042 13.8 0.9 1.6 1 0 0 1 1 1 0 CsbD-like Cwf_Cwc_15 PF04889.12 OAG44662.1 - 9.7e-86 287.5 18.7 1.1e-85 287.3 18.7 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein SDA1 PF05285.12 OAG44662.1 - 0.0071 15.8 18.1 0.0085 15.6 18.1 1.1 1 0 0 1 1 1 1 SDA1 YL1 PF05764.13 OAG44662.1 - 0.037 14.2 20.7 0.046 13.8 20.7 1.2 1 0 0 1 1 1 0 YL1 nuclear protein PA26 PF04636.13 OAG44662.1 - 0.98 8.3 4.5 1.1 8.1 4.5 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) MAJIN PF15077.6 OAG44662.1 - 2.9 7.6 7.9 3.8 7.2 7.2 1.5 1 1 0 1 1 1 0 Membrane-anchored junction protein CDC45 PF02724.14 OAG44662.1 - 5.3 5.2 17.2 6.2 5.0 17.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Roughex PF06020.11 OAG44662.1 - 5.9 5.9 13.8 7.2 5.6 13.8 1.2 1 0 0 1 1 1 0 Drosophila roughex protein ThrE PF06738.12 OAG44663.1 - 2.5e-60 203.8 17.1 2e-56 191.1 2.9 2.2 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 OAG44663.1 - 8.2e-10 38.9 36.6 1.6e-09 38.0 15.7 3.0 3 1 0 3 3 3 2 Threonine/Serine exporter, ThrE GDE_N PF12439.8 OAG44663.1 - 0.0087 15.5 0.0 0.016 14.7 0.0 1.3 1 0 0 1 1 1 1 Glycogen debranching enzyme N terminal RNase_PH PF01138.21 OAG44664.1 - 3.7e-21 76.0 0.0 5.8e-21 75.4 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 OAG44664.1 - 7e-12 45.2 0.0 1.4e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 DUF348 PF03990.14 OAG44664.1 - 0.0013 18.5 1.0 0.024 14.4 0.1 2.5 2 0 0 2 2 2 1 G5-linked-Ubiquitin-like domain RT_RNaseH PF17917.1 OAG44664.1 - 0.017 15.4 0.0 4.8 7.5 0.0 2.3 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 OAG44664.1 - 0.072 13.1 0.1 1.8 8.7 0.0 2.3 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase PhoLip_ATPase_C PF16212.5 OAG44665.1 - 6.7e-79 265.2 23.9 6.7e-79 265.2 23.9 2.1 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 OAG44665.1 - 3.3e-25 87.5 5.0 1.1e-24 85.9 5.0 2.0 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 OAG44665.1 - 1.3e-10 41.9 2.5 2e-06 28.3 0.6 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 OAG44665.1 - 2e-10 40.6 0.0 9.8e-10 38.4 0.0 2.1 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 OAG44665.1 - 5.3e-09 35.9 0.0 1.3e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 OAG44665.1 - 0.0039 17.0 0.3 0.027 14.2 0.1 2.0 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Ecl1 PF12855.7 OAG44666.1 - 4.4e-45 155.0 20.4 7.8e-45 154.1 20.4 1.4 1 0 0 1 1 1 1 ECL1/2/3 zinc binding proteins zf-MYND PF01753.18 OAG44666.1 - 0.00023 21.2 2.4 0.00054 20.0 2.4 1.6 1 0 0 1 1 1 1 MYND finger PLATZ PF04640.14 OAG44666.1 - 0.075 13.7 2.2 0.15 12.7 2.2 1.4 1 0 0 1 1 1 0 PLATZ transcription factor zf-FLZ PF04570.14 OAG44666.1 - 0.49 9.9 6.7 3 7.4 6.7 2.0 1 1 0 1 1 1 0 zinc-finger of the FCS-type, C2-C2 DUF2256 PF10013.9 OAG44666.1 - 1.4 9.1 5.6 9.1 6.5 5.6 2.1 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2256) YL1 PF05764.13 OAG44667.1 - 1.5e-50 172.6 36.0 1.5e-50 172.6 36.0 3.5 3 1 0 3 3 3 1 YL1 nuclear protein YL1_C PF08265.11 OAG44667.1 - 6e-07 29.1 0.0 9.8e-07 28.4 0.0 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain BTV_NS2 PF04514.12 OAG44667.1 - 0.6 8.9 7.3 1.2 7.9 7.3 1.5 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 AP_endonuc_2 PF01261.24 OAG44668.1 - 3.5e-30 105.0 0.0 5e-30 104.5 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel p450 PF00067.22 OAG44669.1 - 2.9e-76 257.1 0.0 3.8e-76 256.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4708 PF15813.5 OAG44669.1 - 0.044 12.9 0.0 0.073 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4708) bZIP_1 PF00170.21 OAG44670.1 - 2e-07 31.0 11.2 3e-07 30.4 11.2 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 OAG44670.1 - 4.2e-05 24.0 4.5 6.5e-05 23.4 4.5 1.2 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_2 PF07716.15 OAG44670.1 - 0.00012 22.1 11.6 0.00017 21.6 11.6 1.2 1 0 0 1 1 1 1 Basic region leucine zipper Dynamitin PF04912.14 OAG44670.1 - 0.029 13.7 2.6 0.035 13.4 2.6 1.1 1 0 0 1 1 1 0 Dynamitin Macoilin PF09726.9 OAG44670.1 - 0.07 11.7 2.9 0.085 11.4 2.9 1.0 1 0 0 1 1 1 0 Macoilin family CDC45 PF02724.14 OAG44670.1 - 0.2 9.9 4.1 0.25 9.6 4.1 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF1501 PF07394.12 OAG44670.1 - 0.67 8.9 4.8 1.2 8.1 4.8 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1501) FAM199X PF15814.5 OAG44670.1 - 5.4 6.0 10.7 1.4 7.9 4.2 2.0 1 1 1 2 2 2 0 Protein family FAM199X Methyltransf_2 PF00891.18 OAG44671.1 - 4.8e-27 94.6 0.0 7.4e-27 94.0 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_12 PF08242.12 OAG44671.1 - 0.0016 19.1 0.0 0.0034 18.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG44671.1 - 0.0029 18.3 0.0 0.0084 16.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain HD PF01966.22 OAG44672.1 - 8.9e-05 22.7 0.4 0.00077 19.7 0.4 2.4 2 1 0 2 2 2 1 HD domain HBB PF06777.11 OAG44672.1 - 0.007 16.1 0.1 0.011 15.4 0.1 1.3 1 0 0 1 1 1 1 Helical and beta-bridge domain Nore1-SARAH PF16517.5 OAG44672.1 - 0.083 12.8 1.2 0.22 11.5 1.2 1.7 1 0 0 1 1 1 0 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain GRASP55_65 PF04495.14 OAG44673.1 - 1.7e-39 135.3 0.0 1.6e-38 132.1 0.0 2.0 2 0 0 2 2 2 1 GRASP55/65 PDZ-like domain zf-RING_2 PF13639.6 OAG44675.1 - 0.00056 20.2 4.4 0.0014 18.9 4.4 1.7 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.8 OAG44675.1 - 0.012 15.8 5.3 0.023 14.8 5.3 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain C1_1 PF00130.22 OAG44675.1 - 0.017 15.0 2.0 0.046 13.6 2.0 1.8 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-rbx1 PF12678.7 OAG44675.1 - 0.25 11.6 5.3 0.58 10.5 5.3 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain PHD_4 PF16866.5 OAG44675.1 - 0.51 10.5 7.5 1.3 9.2 7.3 1.8 1 1 0 1 1 1 0 PHD-finger DUF3246 PF11596.8 OAG44675.1 - 0.57 9.6 15.6 0.043 13.2 10.9 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) Pox_MCEL PF03291.16 OAG44676.1 - 4.9e-65 219.8 0.0 4.6e-62 210.1 0.0 2.6 1 1 0 1 1 1 1 mRNA capping enzyme Methyltransf_25 PF13649.6 OAG44676.1 - 1.4e-10 41.7 0.0 5.2e-05 23.9 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 OAG44676.1 - 6.5e-09 36.4 0.0 3.5e-08 34.1 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG44676.1 - 1.7e-08 35.0 0.0 3.5e-07 30.8 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG44676.1 - 7.8e-07 29.0 0.0 0.00013 21.8 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 OAG44676.1 - 3.5e-05 23.7 0.0 6.7e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 OAG44676.1 - 0.016 14.4 0.0 0.027 13.6 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Raftlin PF15250.6 OAG44676.1 - 0.5 9.1 2.8 1.8 7.2 0.0 2.1 2 0 0 2 2 2 0 Raftlin Sugar_tr PF00083.24 OAG44677.1 - 9.9e-113 377.4 29.0 1.2e-112 377.1 29.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG44677.1 - 2e-19 69.7 33.9 2e-19 69.7 33.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sulfatase PF00884.23 OAG44678.1 - 1.1e-73 248.4 0.0 1.5e-73 247.9 0.0 1.2 1 0 0 1 1 1 1 Sulfatase DUF4470 PF14737.6 OAG44678.1 - 1.6e-26 92.3 0.9 4.1e-26 91.0 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4470) zf-MYND PF01753.18 OAG44678.1 - 4.8e-05 23.4 5.8 0.00012 22.1 5.8 1.7 1 0 0 1 1 1 1 MYND finger DUF4994 PF16385.5 OAG44678.1 - 0.00011 22.1 0.0 0.00023 21.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF4976 PF16347.5 OAG44678.1 - 0.01 16.1 0.1 0.058 13.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4976) Sulfatase_C PF14707.6 OAG44678.1 - 0.011 16.4 0.1 0.18 12.6 0.1 2.6 1 1 0 1 1 1 0 C-terminal region of aryl-sulfatase zf-C6H2 PF15801.5 OAG44678.1 - 0.26 11.6 2.8 0.56 10.6 2.8 1.5 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Rax2 PF12768.7 OAG44679.1 - 0.00067 19.2 0.0 0.0011 18.5 0.0 1.3 1 0 0 1 1 1 1 Cortical protein marker for cell polarity MGC-24 PF05283.11 OAG44679.1 - 0.11 13.0 5.4 0.18 12.3 5.4 1.4 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Sporozoite_P67 PF05642.11 OAG44679.1 - 0.88 7.6 13.9 1.1 7.3 13.9 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CCDC24 PF15669.5 OAG44679.1 - 2.3 8.0 8.5 3.5 7.4 8.5 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family ADH_N_2 PF16884.5 OAG44681.1 - 2.5e-24 85.3 0.0 4.5e-24 84.4 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 OAG44681.1 - 2.8e-22 79.1 0.0 5.8e-22 78.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAG44681.1 - 3e-08 34.8 0.0 5.7e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DapB_N PF01113.20 OAG44681.1 - 0.097 12.8 0.1 0.16 12.1 0.1 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus zf-RING_2 PF13639.6 OAG44682.1 - 8e-09 35.7 2.1 1.2e-08 35.2 2.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 OAG44682.1 - 2.4e-05 24.5 3.3 0.00023 21.4 3.3 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 OAG44682.1 - 0.00016 21.6 5.4 0.00028 20.8 5.4 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 OAG44682.1 - 0.0024 17.9 0.1 0.0036 17.3 0.1 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 OAG44682.1 - 0.0093 15.7 3.7 0.018 14.8 3.7 1.5 1 0 0 1 1 1 1 RING-like zinc finger zinc_ribbon_9 PF14369.6 OAG44682.1 - 0.027 14.7 0.1 0.069 13.4 0.1 1.7 1 0 0 1 1 1 0 zinc-ribbon zf-C3HC4_2 PF13923.6 OAG44682.1 - 0.03 14.2 2.9 0.083 12.8 3.0 1.6 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAG44682.1 - 0.16 11.8 1.2 0.3 11.0 1.2 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) UCH_1 PF13423.6 OAG44683.1 - 1.3e-94 317.4 0.0 1.7e-94 317.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.24 OAG44683.1 - 7.6e-14 52.6 0.0 1.8e-13 51.3 0.0 1.7 2 0 0 2 2 2 1 Exonuclease UCH PF00443.29 OAG44683.1 - 0.0068 15.9 0.0 0.016 14.7 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ANAPC4_WD40 PF12894.7 OAG44683.1 - 0.043 14.1 0.0 8.3 6.8 0.0 2.7 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain MARVEL PF01284.23 OAG44684.1 - 0.0049 16.9 16.2 0.011 15.8 16.4 1.4 1 1 0 1 1 1 1 Membrane-associating domain DUF2070 PF09843.9 OAG44684.1 - 0.13 10.5 7.7 0.16 10.2 7.7 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) zf-RRN7 PF11781.8 OAG44684.1 - 0.14 11.9 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Fungal_trans_2 PF11951.8 OAG44686.1 - 0.011 14.6 0.2 0.077 11.8 0.2 2.1 1 1 0 1 1 1 0 Fungal specific transcription factor domain FAM217 PF15344.6 OAG44686.1 - 6.1 6.7 12.3 1 9.2 8.6 1.5 2 0 0 2 2 2 0 FAM217 family PHY PF00360.20 OAG44687.1 - 1.2e-28 99.6 0.0 5e-27 94.4 0.0 2.3 2 0 0 2 2 2 1 Phytochrome region HATPase_c PF02518.26 OAG44687.1 - 7.6e-17 61.8 1.8 8.7e-17 61.6 0.5 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 OAG44687.1 - 5.2e-14 52.4 0.0 2.1e-13 50.4 0.0 2.1 2 1 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 OAG44687.1 - 1.7e-12 47.2 0.6 1.7e-12 47.2 0.6 2.0 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain GAF PF01590.26 OAG44687.1 - 2.6e-12 47.5 0.0 1.5e-11 45.0 0.0 2.2 2 0 0 2 2 2 1 GAF domain PAS_2 PF08446.11 OAG44687.1 - 2e-08 34.8 0.0 6.1e-08 33.3 0.0 1.9 1 0 0 1 1 1 1 PAS fold HATPase_c_3 PF13589.6 OAG44687.1 - 0.025 14.4 0.0 0.056 13.3 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ldh_2 PF02615.14 OAG44688.1 - 4.2e-127 423.9 0.2 4.7e-127 423.7 0.2 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase Questin_oxidase PF14027.6 OAG44689.1 - 2.8e-83 280.3 1.6 3.3e-83 280.1 1.6 1.0 1 0 0 1 1 1 1 Questin oxidase-like Sugar_tr PF00083.24 OAG44692.1 - 7.2e-75 252.6 24.7 8.4e-75 252.4 24.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG44692.1 - 4.1e-17 62.1 35.8 1.6e-11 43.7 12.9 2.9 1 1 2 3 3 3 3 Major Facilitator Superfamily MFS_1_like PF12832.7 OAG44692.1 - 0.0019 17.2 1.3 0.0019 17.2 1.3 2.4 2 1 0 2 2 2 1 MFS_1 like family ABC2_membrane_3 PF12698.7 OAG44692.1 - 0.0062 15.7 1.5 0.0062 15.7 1.5 2.2 3 0 0 3 3 3 1 ABC-2 family transporter protein Phage_holin_7_1 PF16081.5 OAG44692.1 - 0.049 13.8 0.8 0.12 12.5 0.8 1.6 1 0 0 1 1 1 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family DUF3363 PF11843.8 OAG44693.1 - 0.0013 17.8 0.0 0.002 17.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3363) F-box PF00646.33 OAG44693.1 - 0.0086 15.9 0.7 0.036 13.9 0.1 2.2 2 0 0 2 2 2 1 F-box domain Alpha-amylase PF00128.24 OAG44694.1 - 6.8e-115 384.2 0.1 9.4e-115 383.8 0.1 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF3459 PF11941.8 OAG44694.1 - 0.00018 21.8 0.1 0.00065 20.0 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3459) Malt_amylase_C PF16657.5 OAG44694.1 - 0.14 12.3 0.0 0.34 11.1 0.0 1.6 1 0 0 1 1 1 0 Maltogenic Amylase, C-terminal domain zf-DNL PF05180.12 OAG44695.1 - 7.6e-26 89.8 0.5 1.1e-25 89.3 0.5 1.3 1 0 0 1 1 1 1 DNL zinc finger Cullin PF00888.22 OAG44696.1 - 1.5e-190 634.9 15.9 2.1e-190 634.5 15.9 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 OAG44696.1 - 2.1e-26 91.7 0.2 2.1e-26 91.7 0.2 2.8 3 0 0 3 3 3 1 Cullin protein neddylation domain zf-CCHC_5 PF14787.6 OAG44697.1 - 0.0028 17.3 0.1 0.0048 16.6 0.1 1.3 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger BTB PF00651.31 OAG44697.1 - 0.0095 16.2 0.0 0.02 15.1 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain TPR_12 PF13424.6 OAG44699.1 - 1.9e-13 50.5 14.9 0.0002 21.6 0.0 6.4 5 1 1 7 7 7 4 Tetratricopeptide repeat NACHT PF05729.12 OAG44699.1 - 2.8e-07 30.6 0.3 1.4e-06 28.3 0.3 2.2 1 1 0 1 1 1 1 NACHT domain TPR_10 PF13374.6 OAG44699.1 - 1.6e-05 24.6 2.7 0.91 9.5 0.0 5.6 5 0 0 5 5 5 1 Tetratricopeptide repeat AAA_16 PF13191.6 OAG44699.1 - 5.3e-05 23.7 5.3 5.3e-05 23.7 0.2 3.1 3 0 0 3 3 3 1 AAA ATPase domain AAA PF00004.29 OAG44699.1 - 0.00045 20.7 0.0 0.0013 19.1 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TPR_MalT PF17874.1 OAG44699.1 - 0.00094 18.7 0.4 0.00094 18.7 0.4 2.1 3 1 0 3 3 3 1 MalT-like TPR region AAA_22 PF13401.6 OAG44699.1 - 0.0013 19.0 0.0 0.011 16.1 0.0 2.6 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 OAG44699.1 - 0.021 15.2 0.0 0.06 13.7 0.0 1.8 1 0 0 1 1 1 0 RNA helicase TPR_2 PF07719.17 OAG44699.1 - 0.036 14.2 3.8 13 6.2 0.0 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat ATPase_2 PF01637.18 OAG44699.1 - 0.044 13.7 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea DUF2075 PF09848.9 OAG44699.1 - 0.052 12.8 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_5 PF07728.14 OAG44699.1 - 0.077 13.0 0.0 0.25 11.3 0.0 1.9 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) DAP3 PF10236.9 OAG44699.1 - 0.11 11.7 0.0 0.23 10.6 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 TPR_14 PF13428.6 OAG44699.1 - 1.6 9.7 0.0 1.6 9.7 0.0 4.9 6 1 1 7 7 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 OAG44699.1 - 2.4 8.7 7.4 29 5.3 0.3 3.9 4 1 0 4 4 4 0 Tetratricopeptide repeat SLD5_C PF16922.5 OAG44700.1 - 1.2e-12 47.8 0.7 2e-12 47.1 0.7 1.4 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus Sld5 PF05916.11 OAG44700.1 - 1.1e-05 25.8 0.0 2e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 GINS complex protein UBM PF14377.6 OAG44700.1 - 0.08 12.4 0.0 0.22 11.0 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin binding region SusD-like PF12741.7 OAG44700.1 - 0.12 11.2 0.0 0.17 10.8 0.0 1.1 1 0 0 1 1 1 0 Susd and RagB outer membrane lipoprotein Synapsin_N PF10581.9 OAG44700.1 - 1.6 8.8 5.3 1.1 9.3 0.5 2.6 1 1 1 2 2 2 0 Synapsin N-terminal SWI-SNF_Ssr4 PF08549.10 OAG44701.1 - 6.4e-187 623.5 32.5 1.9e-185 618.6 32.5 2.0 1 1 0 1 1 1 1 Fungal domain of unknown function (DUF1750) Ppx-GppA PF02541.16 OAG44702.1 - 9.6e-45 153.2 0.0 7e-44 150.4 0.0 1.9 1 1 0 1 1 1 1 Ppx/GppA phosphatase family Sec10 PF07393.11 OAG44702.1 - 0.00062 18.3 0.0 0.00089 17.8 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 GDA1_CD39 PF01150.17 OAG44702.1 - 0.025 13.3 0.1 0.047 12.4 0.1 1.3 1 0 0 1 1 1 0 GDA1/CD39 (nucleoside phosphatase) family Cas_Cas5d PF09704.10 OAG44702.1 - 0.18 11.7 0.1 0.57 10.0 0.0 1.8 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cas5) HET PF06985.11 OAG44703.1 - 1.1e-37 129.6 0.1 6.5e-30 104.4 0.0 2.3 2 0 0 2 2 2 2 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.16 OAG44704.1 - 2.5e-24 85.9 16.6 3.7e-24 85.3 16.6 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1304 PF06993.12 OAG44704.1 - 5.1 7.1 7.1 1.3 9.0 1.8 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1304) DLH PF01738.18 OAG44705.1 - 6.1e-30 104.4 0.0 7.3e-30 104.1 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family CH PF00307.31 OAG44706.1 - 3.1e-71 236.5 0.0 2.9e-18 66.0 0.0 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.6 OAG44706.1 - 3e-08 34.0 1.6 2.3e-07 31.1 1.0 2.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 OAG44706.1 - 1.3e-05 24.4 1.0 0.42 10.3 0.1 3.6 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 OAG44706.1 - 0.0014 18.4 4.6 0.013 15.4 0.0 3.4 4 0 0 4 4 4 1 EF-hand domain CAMSAP_CH PF11971.8 OAG44706.1 - 0.0077 16.0 0.0 0.16 11.8 0.0 3.0 4 0 0 4 4 4 1 CAMSAP CH domain DDHD PF02862.17 OAG44707.1 - 1e-60 205.7 1.4 1.5e-59 201.9 0.1 2.6 2 0 0 2 2 2 1 DDHD domain DUF676 PF05057.14 OAG44707.1 - 0.042 13.3 0.2 0.5 9.8 0.0 2.5 3 0 0 3 3 3 0 Putative serine esterase (DUF676) AAR2 PF05282.11 OAG44707.1 - 5.5 6.3 8.3 0.095 12.1 0.5 1.9 2 0 0 2 2 2 0 AAR2 protein MFS_1 PF07690.16 OAG44708.1 - 5e-18 65.1 32.9 5e-18 65.1 32.9 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG44708.1 - 7e-06 25.2 6.9 7e-06 25.2 6.9 2.6 1 1 2 3 3 3 1 Sugar (and other) transporter HlyIII PF03006.20 OAG44708.1 - 1.1 8.9 9.6 0.089 12.5 0.3 2.4 2 0 0 2 2 2 0 Haemolysin-III related Ysc84 PF04366.12 OAG44709.1 - 1.9e-41 140.8 0.3 3.1e-41 140.1 0.3 1.3 1 0 0 1 1 1 1 Las17-binding protein actin regulator SH3_1 PF00018.28 OAG44709.1 - 1.8e-14 53.0 0.3 5.8e-14 51.4 0.1 1.9 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 OAG44709.1 - 1.1e-13 50.6 0.2 2.9e-13 49.3 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.6 OAG44709.1 - 1.1e-10 41.2 0.0 2.1e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain EF_assoc_2 PF08356.12 OAG44710.1 - 1.1e-34 118.2 0.0 2.1e-34 117.3 0.0 1.5 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.12 OAG44710.1 - 1.3e-29 101.6 0.8 2.9e-29 100.5 0.8 1.6 1 0 0 1 1 1 1 EF hand associated Ras PF00071.22 OAG44710.1 - 2e-25 89.2 0.0 8.9e-15 54.7 0.0 2.2 2 0 0 2 2 2 2 Ras family Roc PF08477.13 OAG44710.1 - 1.9e-13 50.7 0.0 1.1e-08 35.3 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 OAG44710.1 - 1.8e-08 34.5 0.0 0.00012 22.2 0.0 2.9 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.6 OAG44710.1 - 0.00045 20.5 0.0 1.1 9.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain Dynamin_N PF00350.23 OAG44710.1 - 0.00064 19.8 0.0 0.28 11.2 0.0 3.0 3 0 0 3 3 3 1 Dynamin family AAA_29 PF13555.6 OAG44710.1 - 0.00065 19.4 0.1 0.29 10.9 0.0 2.7 3 0 0 3 3 2 1 P-loop containing region of AAA domain AAA_16 PF13191.6 OAG44710.1 - 0.0017 18.8 0.1 2.5 8.4 0.0 2.8 3 0 0 3 3 3 2 AAA ATPase domain EF-hand_7 PF13499.6 OAG44710.1 - 0.0031 17.9 2.3 0.24 11.9 0.8 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 OAG44710.1 - 0.0037 16.7 2.2 0.26 10.9 0.4 2.6 2 0 0 2 2 2 1 EF hand EF-hand_10 PF14788.6 OAG44710.1 - 0.0076 16.1 2.2 0.2 11.5 0.2 2.7 3 0 0 3 3 2 1 EF hand GTP_EFTU PF00009.27 OAG44710.1 - 0.011 15.2 0.0 6.3 6.3 0.0 3.1 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain RNA_helicase PF00910.22 OAG44710.1 - 0.014 15.7 0.0 0.28 11.6 0.0 2.5 2 0 0 2 2 2 0 RNA helicase RsgA_GTPase PF03193.16 OAG44710.1 - 0.033 14.1 0.0 1 9.3 0.0 2.7 2 0 0 2 2 2 0 RsgA GTPase EF-hand_6 PF13405.6 OAG44710.1 - 0.04 13.9 2.7 0.98 9.5 0.3 2.7 2 0 0 2 2 2 0 EF-hand domain AAA_18 PF13238.6 OAG44710.1 - 0.074 13.6 0.1 1.7 9.2 0.0 2.9 3 1 0 3 3 3 0 AAA domain AAA_28 PF13521.6 OAG44710.1 - 0.1 12.9 0.0 5.9 7.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 OAG44710.1 - 0.18 12.3 0.0 1.8 9.1 0.0 2.3 2 0 0 2 2 2 0 ABC transporter Septin PF00735.18 OAG44710.1 - 0.2 10.9 0.0 0.49 9.6 0.0 1.6 1 0 0 1 1 1 0 Septin AAA_25 PF13481.6 OAG44710.1 - 0.2 11.2 0.1 17 4.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain EF-hand_8 PF13833.6 OAG44710.1 - 0.33 10.9 2.8 7.5 6.5 0.1 2.9 2 0 0 2 2 2 0 EF-hand domain pair Cupin_5 PF06172.11 OAG44711.1 - 7.2e-49 165.6 0.0 1e-48 165.1 0.0 1.2 1 0 0 1 1 1 1 Cupin superfamily (DUF985) Proteasome PF00227.26 OAG44712.1 - 4.5e-47 160.0 0.1 5.4e-47 159.7 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Corona_S2 PF01601.16 OAG44715.1 - 0.068 11.7 11.4 0.09 11.2 11.4 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein RCR PF12273.8 OAG44716.1 - 1.9e-21 76.9 9.7 2.3e-21 76.7 9.7 1.1 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red SARAF PF06682.12 OAG44716.1 - 0.00012 21.8 0.2 0.00014 21.7 0.2 1.2 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis Ferric_reduct PF01794.19 OAG44716.1 - 0.04 14.0 0.3 0.058 13.5 0.3 1.2 1 0 0 1 1 1 0 Ferric reductase like transmembrane component DUF4381 PF14316.6 OAG44716.1 - 0.31 11.3 2.7 0.49 10.6 2.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Arf PF00025.21 OAG44717.1 - 4.2e-42 143.6 0.0 5e-42 143.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 OAG44717.1 - 6.1e-19 68.2 0.0 7.6e-19 67.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAG44717.1 - 4.6e-15 55.9 0.0 6.7e-15 55.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 OAG44717.1 - 5.6e-10 39.3 0.0 8.1e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OAG44717.1 - 1e-07 31.6 0.0 1.2e-07 31.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 OAG44717.1 - 4.8e-07 29.4 0.0 5.4e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 OAG44717.1 - 9.1e-05 22.0 0.3 0.00069 19.2 0.0 2.2 2 1 0 2 2 2 1 Ferrous iron transport protein B G-alpha PF00503.20 OAG44717.1 - 0.00019 20.7 0.0 0.00064 19.0 0.0 1.8 1 1 1 2 2 2 1 G-protein alpha subunit Dynamin_N PF00350.23 OAG44717.1 - 0.00027 21.0 0.0 0.078 13.0 0.1 2.2 1 1 0 2 2 2 2 Dynamin family ABC_tran PF00005.27 OAG44717.1 - 0.031 14.8 0.0 0.035 14.6 0.0 1.3 1 1 0 1 1 1 0 ABC transporter PduV-EutP PF10662.9 OAG44717.1 - 0.2 11.4 0.0 1.3 8.7 0.0 2.2 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation MFS_1 PF07690.16 OAG44718.1 - 5.2e-30 104.6 27.1 6.8e-30 104.2 27.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Trp_oprn_chp PF09534.10 OAG44718.1 - 0.15 11.9 0.3 0.28 10.9 0.3 1.5 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Oxidored_FMN PF00724.20 OAG44721.1 - 6.1e-88 295.3 0.0 7.1e-88 295.1 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Pkinase PF00069.25 OAG44722.1 - 1.3e-34 119.8 1.7 2.9e-26 92.4 0.0 3.8 3 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAG44722.1 - 2.3e-14 53.3 0.3 1.7e-12 47.2 0.0 3.0 2 1 1 3 3 3 1 Protein tyrosine kinase APH PF01636.23 OAG44722.1 - 0.0014 18.6 0.6 0.008 16.1 0.3 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 OAG44722.1 - 0.036 13.0 0.1 0.057 12.4 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF746 PF05344.11 OAG44722.1 - 0.052 13.4 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 Domain of Unknown Function (DUF746) Haspin_kinase PF12330.8 OAG44722.1 - 0.14 11.1 0.1 0.26 10.2 0.1 1.4 1 0 0 1 1 1 0 Haspin like kinase domain IMS PF00817.20 OAG44723.1 - 6.9e-42 143.0 0.0 1.4e-41 142.0 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family REV1_C PF16727.5 OAG44723.1 - 6.9e-22 77.7 1.1 1.5e-21 76.6 1.1 1.6 1 0 0 1 1 1 1 DNA repair protein REV1 C-terminal domain IMS_C PF11799.8 OAG44723.1 - 2.8e-13 50.6 0.0 8.2e-13 49.1 0.0 1.8 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain UBM PF14377.6 OAG44723.1 - 5.9e-13 47.8 19.6 9.4e-06 24.9 0.5 4.2 4 0 0 4 4 4 3 Ubiquitin binding region BRCT_2 PF16589.5 OAG44723.1 - 3.3e-10 40.2 0.0 9e-10 38.8 0.0 1.8 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 OAG44723.1 - 6.1e-06 26.5 0.0 4.3e-05 23.8 0.0 2.5 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 OAG44723.1 - 0.00078 19.3 0.0 0.0024 17.8 0.0 1.9 1 0 0 1 1 1 1 twin BRCT domain IMS_HHH PF11798.8 OAG44723.1 - 0.0013 19.0 0.4 0.011 16.1 0.1 2.6 2 0 0 2 2 2 1 IMS family HHH motif mCpol PF18182.1 OAG44723.1 - 0.0014 18.9 0.0 0.0049 17.2 0.0 1.9 1 0 0 1 1 1 1 minimal CRISPR polymerase domain DUF1805 PF08827.11 OAG44723.1 - 0.036 14.4 0.0 0.11 12.8 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) NPL PF17800.1 OAG44724.1 - 9.3e-29 100.1 5.1 9.3e-29 100.1 5.1 3.2 2 2 0 2 2 2 1 Nucleoplasmin-like domain FKBP_C PF00254.28 OAG44724.1 - 4e-28 97.6 0.0 1.9e-27 95.4 0.0 2.1 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase Utp14 PF04615.13 OAG44724.1 - 0.047 12.3 43.4 0.067 11.8 43.4 1.1 1 0 0 1 1 1 0 Utp14 protein Macoilin PF09726.9 OAG44724.1 - 0.14 10.7 8.6 0.27 9.8 8.6 1.3 1 0 0 1 1 1 0 Macoilin family GCV_T PF01571.21 OAG44725.1 - 8.4e-70 235.1 0.0 2e-69 233.8 0.0 1.6 2 0 0 2 2 2 1 Aminomethyltransferase folate-binding domain DAO PF01266.24 OAG44725.1 - 2.6e-45 155.5 0.1 4.9e-45 154.7 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase GCV_T_C PF08669.11 OAG44725.1 - 1.3e-22 79.4 0.0 3.9e-22 78.0 0.0 1.9 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain FAO_M PF16350.5 OAG44725.1 - 3.2e-19 69.0 0.0 6.2e-19 68.1 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase central domain Pyr_redox PF00070.27 OAG44725.1 - 8.2e-05 23.1 0.1 0.082 13.5 0.1 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAG44725.1 - 9e-05 21.8 0.1 0.23 10.6 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAG44725.1 - 0.0017 18.4 0.2 0.42 10.6 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding TrkA_N PF02254.18 OAG44725.1 - 0.0067 16.7 0.7 0.019 15.2 0.1 2.1 3 0 0 3 3 3 1 TrkA-N domain SoxG PF04268.12 OAG44725.1 - 0.017 15.3 0.0 0.046 13.9 0.0 1.7 1 0 0 1 1 1 0 Sarcosine oxidase, gamma subunit family NAD_binding_8 PF13450.6 OAG44725.1 - 0.035 14.3 0.0 0.13 12.5 0.0 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain F420_oxidored PF03807.17 OAG44725.1 - 0.064 13.8 0.1 0.31 11.7 0.1 2.1 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 OAG44725.1 - 0.13 12.4 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ThiF PF00899.21 OAG44725.1 - 0.19 11.1 0.1 0.35 10.2 0.1 1.4 1 0 0 1 1 1 0 ThiF family Ring_hydroxyl_A PF00848.19 OAG44726.1 - 3.2e-23 82.8 3.2 1.8e-20 73.9 3.2 2.4 1 1 0 1 1 1 1 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.26 OAG44726.1 - 6.7e-14 51.6 0.0 1.3e-13 50.7 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Fungal_trans PF04082.18 OAG44726.1 - 0.008 15.2 0.0 0.022 13.8 0.0 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain DAO PF01266.24 OAG44727.1 - 1.5e-35 123.4 1.4 3.6e-35 122.2 1.4 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 OAG44727.1 - 4.5e-08 33.2 0.7 0.0051 16.8 0.2 2.6 3 0 0 3 3 3 2 FAD-NAD(P)-binding GIDA PF01134.22 OAG44727.1 - 8.7e-07 28.4 0.1 8.4e-06 25.1 0.1 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 OAG44727.1 - 4.3e-06 26.2 0.2 0.027 13.7 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 OAG44727.1 - 6.2e-05 22.0 0.1 0.0033 16.4 0.0 2.1 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox_3 PF13738.6 OAG44727.1 - 0.00011 21.5 0.1 0.19 10.9 0.1 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG44727.1 - 0.00021 21.4 0.1 0.00083 19.5 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 OAG44727.1 - 0.003 16.7 0.1 2 7.4 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein ApbA PF02558.16 OAG44727.1 - 0.044 13.4 0.0 0.084 12.5 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 OAG44727.1 - 0.16 11.9 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 OAG44727.1 - 0.16 12.4 0.0 0.29 11.6 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding DUF3591 PF12157.8 OAG44728.1 - 1.5e-172 574.2 7.1 1.6e-172 574.2 5.6 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3591) zf-CCHC PF00098.23 OAG44728.1 - 0.0088 16.1 0.7 0.0088 16.1 0.7 2.0 2 0 0 2 2 2 1 Zinc knuckle K_channel_TID PF07941.11 OAG44728.1 - 0.076 13.5 6.0 0.16 12.4 6.0 1.5 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain OrfB_Zn_ribbon PF07282.11 OAG44728.1 - 0.3 11.0 1.8 0.69 9.9 1.8 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Methyltransf_15 PF09445.10 OAG44729.1 - 6e-51 172.3 0.0 7.9e-51 171.9 0.0 1.1 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Met_10 PF02475.16 OAG44729.1 - 7.3e-06 25.9 0.0 9.6e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein UPF0020 PF01170.18 OAG44729.1 - 8.8e-05 22.3 1.0 0.0033 17.1 0.6 3.1 1 1 1 2 2 2 1 Putative RNA methylase family UPF0020 Methyltransf_25 PF13649.6 OAG44729.1 - 0.00016 22.3 0.0 0.00031 21.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 OAG44729.1 - 0.00036 20.5 0.0 0.00057 19.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG44729.1 - 0.0049 17.5 0.0 0.0095 16.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 OAG44729.1 - 0.011 15.4 0.0 0.026 14.2 0.0 1.7 1 1 0 1 1 1 0 Conserved hypothetical protein 95 MTS PF05175.14 OAG44729.1 - 0.012 15.1 0.0 0.02 14.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.13 OAG44729.1 - 0.037 13.4 0.0 0.054 12.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_5 PF01795.19 OAG44729.1 - 0.21 11.0 0.0 0.26 10.8 0.0 1.3 1 1 0 1 1 1 0 MraW methylase family RED_N PF07808.13 OAG44730.1 - 2e-08 34.1 3.6 2e-08 34.1 3.6 2.3 2 0 0 2 2 2 1 RED-like protein N-terminal region Glyco_hydro_cc PF11790.8 OAG44731.1 - 1.7e-61 207.9 0.3 2.2e-61 207.5 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core DUF3433 PF11915.8 OAG44732.1 - 2.2e-34 117.8 18.9 1.6e-18 66.9 1.0 3.7 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) Citrate_ly_lig PF08218.11 OAG44732.1 - 0.13 11.9 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Citrate lyase ligase C-terminal domain MHYT PF03707.16 OAG44732.1 - 0.38 10.9 5.3 19 5.5 0.1 3.8 3 0 0 3 3 3 0 Bacterial signalling protein N terminal repeat TPR_12 PF13424.6 OAG44733.1 - 7.9e-05 22.9 0.6 3.6 8.0 0.0 3.7 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 OAG44733.1 - 0.00022 21.2 2.2 3 8.3 0.1 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 OAG44733.1 - 0.0054 16.8 1.1 0.48 10.7 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 OAG44733.1 - 0.0099 16.4 2.4 6.4 7.4 0.2 3.7 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 OAG44733.1 - 0.073 13.7 2.6 1.9 9.3 0.2 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_21 PF09976.9 OAG44733.1 - 0.076 12.7 1.5 2 8.1 0.2 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat-like domain RPN7 PF10602.9 OAG44733.1 - 0.079 12.7 0.0 2.4 7.8 0.0 2.7 3 0 0 3 3 3 0 26S proteasome subunit RPN7 TPR_1 PF00515.28 OAG44733.1 - 0.19 11.6 1.1 63 3.6 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 OAG44733.1 - 0.4 11.6 8.9 16 6.7 0.1 5.2 6 0 0 6 6 6 0 Tetratricopeptide repeat SRAP PF02586.14 OAG44734.1 - 3.3e-79 265.5 0.0 4.5e-79 265.0 0.0 1.2 1 0 0 1 1 1 1 SOS response associated peptidase (SRAP) LRR_8 PF13855.6 OAG44735.1 - 0.098 12.4 0.5 33 4.3 0.0 4.1 5 0 0 5 5 5 0 Leucine rich repeat L31 PF09784.9 OAG44736.1 - 6.4e-46 155.0 1.1 7.1e-46 154.8 1.1 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 Cas_APE2256 PF09651.10 OAG44736.1 - 0.087 12.7 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_APE2256) Acyltransferase PF01553.21 OAG44737.1 - 6.1e-12 45.3 0.0 2.7e-11 43.3 0.0 1.9 1 1 0 1 1 1 1 Acyltransferase Malate_synthase PF01274.22 OAG44737.1 - 0.14 10.3 0.0 0.2 9.9 0.0 1.1 1 0 0 1 1 1 0 Malate synthase Rad21_Rec8_N PF04825.13 OAG44738.1 - 1.8e-37 127.8 0.3 4.6e-37 126.6 0.0 1.7 2 0 0 2 2 2 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 OAG44738.1 - 1e-07 31.1 0.1 2.3e-07 30.0 0.1 1.6 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein FAM212 PF15342.6 OAG44738.1 - 0.037 13.8 0.8 0.14 11.9 0.8 2.0 1 0 0 1 1 1 0 FAM212 family E1-E2_ATPase PF00122.20 OAG44739.1 - 5.8e-49 166.1 0.1 5.8e-49 166.1 0.1 2.6 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 OAG44739.1 - 5.4e-45 153.3 1.2 5.4e-45 153.3 1.2 2.4 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 OAG44739.1 - 1.2e-21 78.0 0.9 1.5e-20 74.4 0.9 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 OAG44739.1 - 9.6e-20 70.0 0.2 1.9e-19 69.1 0.2 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 OAG44739.1 - 3.9e-10 39.7 0.0 8.6e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 OAG44739.1 - 2.5e-06 27.4 1.2 6e-05 22.9 1.1 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DAGK_cat PF00781.24 OAG44739.1 - 0.13 11.8 0.2 1.3 8.7 0.0 2.3 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain Flavokinase PF01687.17 OAG44740.1 - 2.9e-32 111.3 0.0 3.9e-32 110.8 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase PAS PF00989.25 OAG44741.1 - 0.0024 17.8 0.1 0.096 12.7 0.0 2.3 2 0 0 2 2 2 1 PAS fold Zn_clus PF00172.18 OAG44741.1 - 0.0082 16.2 9.4 0.0082 16.2 9.4 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF874 PF05917.11 OAG44741.1 - 0.15 11.1 0.3 0.27 10.2 0.3 1.4 1 0 0 1 1 1 0 Helicobacter pylori protein of unknown function (DUF874) MFS_1 PF07690.16 OAG44742.1 - 6.4e-40 137.2 32.7 6.4e-40 137.2 32.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 OAG44742.1 - 6.4e-10 38.1 2.1 1.1e-09 37.4 2.1 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sdh5 PF03937.16 OAG44743.1 - 2e-23 82.1 0.3 6.7e-23 80.4 0.2 1.8 2 0 0 2 2 2 1 Flavinator of succinate dehydrogenase Aldo_ket_red PF00248.21 OAG44744.1 - 5.5e-73 245.7 0.0 6.3e-73 245.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family WD40 PF00400.32 OAG44745.1 - 2.6e-44 148.3 27.5 1.3e-09 38.5 0.2 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG44745.1 - 3.5e-09 36.9 0.4 0.13 12.6 0.0 4.5 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OAG44745.1 - 4.6e-05 22.3 7.7 0.095 11.3 0.2 4.4 1 1 3 5 5 5 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 OAG44745.1 - 0.0034 16.4 0.2 10 5.0 0.0 4.1 2 2 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 OAG44745.1 - 0.011 15.1 0.0 0.98 8.7 0.0 2.3 2 0 0 2 2 2 0 WD40-like domain Cytochrom_D1 PF02239.16 OAG44745.1 - 0.017 13.7 0.0 1.2 7.6 0.0 2.1 2 0 0 2 2 2 0 Cytochrome D1 heme domain PD40 PF07676.12 OAG44745.1 - 0.018 15.0 0.4 22 5.1 0.0 4.4 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat COG4 PF08318.12 OAG44746.1 - 4.3e-123 410.7 0.0 5.8e-123 410.2 0.0 1.2 1 0 0 1 1 1 1 COG4 transport protein CTD_bind PF04818.13 OAG44746.1 - 0.092 13.6 0.0 1.3 9.9 0.0 2.7 2 0 0 2 2 2 0 RNA polymerase II-binding domain. HIP1_clath_bdg PF16515.5 OAG44746.1 - 0.67 10.6 5.2 2.3 8.9 5.2 1.9 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Nsp1_C PF05064.13 OAG44746.1 - 1.9 8.3 5.6 3.3 7.5 0.2 3.2 2 1 1 3 3 3 0 Nsp1-like C-terminal region ANAPC4_WD40 PF12894.7 OAG44747.1 - 9.6e-07 29.0 0.0 1.2 9.5 0.0 4.5 4 2 2 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OAG44747.1 - 1.2e-05 26.0 0.2 0.073 14.0 0.0 4.8 4 0 0 4 4 4 1 WD domain, G-beta repeat PD40 PF07676.12 OAG44747.1 - 0.035 14.0 0.0 7.5 6.6 0.0 2.6 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 OAG44747.1 - 0.061 12.3 0.0 0.13 11.1 0.0 1.6 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Hexokinase_2 PF03727.16 OAG44748.1 - 4.9e-85 284.8 0.0 6.6e-85 284.4 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 OAG44748.1 - 7.3e-75 251.2 0.0 1.4e-74 250.3 0.0 1.4 2 0 0 2 2 2 1 Hexokinase SIR2 PF02146.17 OAG44750.1 - 1.8e-56 190.9 0.0 2.6e-56 190.3 0.0 1.2 1 0 0 1 1 1 1 Sir2 family DEAD PF00270.29 OAG44751.1 - 6.4e-40 136.8 0.5 9.6e-40 136.2 0.5 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAG44751.1 - 1.4e-29 102.7 0.1 8.8e-29 100.1 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG44751.1 - 1.6e-06 28.2 0.0 3.9e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Glyoxalase PF00903.25 OAG44752.1 - 5.2e-13 49.3 0.0 8.2e-13 48.7 0.0 1.3 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 OAG44752.1 - 6.9e-12 45.6 0.0 1e-11 45.0 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 OAG44752.1 - 3.7e-09 37.3 0.0 1.2e-08 35.7 0.0 1.7 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_3 PF13468.6 OAG44752.1 - 0.0049 17.0 0.0 0.011 15.9 0.0 1.5 1 1 0 1 1 1 1 Glyoxalase-like domain Hpre_diP_synt_I PF07456.11 OAG44754.1 - 1.6 8.8 9.5 12 5.9 6.2 2.5 2 1 0 2 2 2 0 Heptaprenyl diphosphate synthase component I Fungal_trans_2 PF11951.8 OAG44755.1 - 7.4e-07 28.3 0.3 3.3e-06 26.2 0.3 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain TIP120 PF08623.10 OAG44756.1 - 8.2e-51 172.1 0.0 1.3e-49 168.2 0.0 2.7 2 0 0 2 2 2 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.6 OAG44756.1 - 6.1e-15 55.4 15.6 0.01 16.2 0.0 9.8 8 3 2 10 10 10 4 HEAT repeats HEAT PF02985.22 OAG44756.1 - 5e-11 41.9 10.8 0.086 13.1 0.0 9.7 9 0 0 9 9 9 3 HEAT repeat RTP1_C1 PF10363.9 OAG44756.1 - 1.2e-08 35.1 1.1 0.00058 20.0 0.0 5.9 7 0 0 7 7 7 1 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 OAG44756.1 - 1.7e-07 31.6 19.9 3.5 8.2 0.0 11.6 11 2 2 13 13 13 2 HEAT-like repeat Cnd1 PF12717.7 OAG44756.1 - 4.3e-06 26.9 6.0 0.21 11.7 0.0 6.0 5 2 1 6 6 6 2 non-SMC mitotic condensation complex subunit 1 DRIM PF07539.12 OAG44756.1 - 2.4e-05 22.9 2.0 0.013 13.9 0.4 3.7 4 1 0 4 4 4 1 Down-regulated in metastasis DUF3385 PF11865.8 OAG44756.1 - 0.00053 19.9 1.3 0.074 13.0 0.0 4.7 5 2 0 5 5 5 1 Domain of unknown function (DUF3385) CLASP_N PF12348.8 OAG44756.1 - 0.002 17.7 0.2 15 5.0 0.0 4.1 3 1 1 4 4 4 0 CLASP N terminal HEAT_PBS PF03130.16 OAG44756.1 - 0.015 15.9 1.9 18 6.3 0.0 5.4 5 0 0 5 5 4 0 PBS lyase HEAT-like repeat Vac14_Fab1_bd PF12755.7 OAG44756.1 - 0.017 15.7 0.1 9.6 6.9 0.0 4.5 6 1 0 6 6 4 0 Vacuolar 14 Fab1-binding region MMS19_N PF14500.6 OAG44756.1 - 0.046 13.3 3.5 7.2 6.1 0.0 4.0 4 0 0 4 4 4 0 Dos2-interacting transcription regulator of RNA-Pol-II DUF3437 PF11919.8 OAG44756.1 - 0.61 10.0 4.0 7.5 6.5 0.0 4.4 5 0 0 5 5 4 0 Domain of unknown function (DUF3437) MMS19_C PF12460.8 OAG44756.1 - 5.2 6.1 15.6 9 5.3 0.5 5.4 4 1 1 6 6 6 0 RNAPII transcription regulator C-terminal SpoIIIAH PF12685.7 OAG44757.1 - 0.035 13.9 9.8 0.13 12.1 9.8 1.8 1 1 0 1 1 1 0 SpoIIIAH-like protein CDC45 PF02724.14 OAG44757.1 - 0.67 8.2 10.4 0.79 7.9 10.4 1.1 1 0 0 1 1 1 0 CDC45-like protein SAPS PF04499.15 OAG44757.1 - 1.3 7.7 5.7 1.5 7.5 5.7 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Presenilin PF01080.17 OAG44757.1 - 2.5 6.8 9.8 3.1 6.5 9.8 1.3 1 0 0 1 1 1 0 Presenilin Hid1 PF12722.7 OAG44757.1 - 5 5.1 8.7 5.1 5.1 8.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein TRAM_LAG1_CLN8 PF03798.16 OAG44758.1 - 3.6e-38 131.3 21.2 6.5e-38 130.5 21.2 1.4 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.11 OAG44758.1 - 3.1e-25 87.6 0.0 3.1e-25 87.6 0.0 2.0 2 0 0 2 2 2 1 TRAM1-like protein p450 PF00067.22 OAG44760.1 - 1.9e-58 198.3 0.0 2.6e-58 197.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 HET PF06985.11 OAG44761.1 - 8.9e-16 58.5 0.1 2e-15 57.4 0.0 1.7 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) zf-C2H2_4 PF13894.6 OAG44762.1 - 6.9e-07 29.6 22.6 0.0015 19.2 4.8 4.5 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2 PF00096.26 OAG44762.1 - 4.7e-06 26.8 28.0 0.0053 17.2 0.8 5.1 4 1 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 OAG44762.1 - 0.00026 20.9 5.9 0.001 19.0 2.4 2.8 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_2 PF12756.7 OAG44762.1 - 0.0063 16.8 9.1 0.092 13.1 1.2 2.3 1 1 1 2 2 2 1 C2H2 type zinc-finger (2 copies) TackOD1 PF18551.1 OAG44762.1 - 0.015 15.0 3.1 0.024 14.3 3.1 1.3 1 0 0 1 1 1 0 Thaumarchaeal output domain 1 Nudix_N_2 PF14803.6 OAG44762.1 - 0.022 14.7 6.4 3.3 7.7 0.1 3.5 3 0 0 3 3 3 0 Nudix N-terminal zf-C2H2_3rep PF18868.1 OAG44762.1 - 0.022 15.4 6.6 0.15 12.8 0.4 2.3 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats Zn-ribbon_8 PF09723.10 OAG44762.1 - 0.025 14.7 6.0 0.77 9.9 1.5 2.9 1 1 1 2 2 2 0 Zinc ribbon domain FOXP-CC PF16159.5 OAG44762.1 - 0.04 14.6 0.7 0.04 14.6 0.7 2.5 2 1 1 3 3 3 0 FOXP coiled-coil domain zf-C2H2_jaz PF12171.8 OAG44762.1 - 0.068 13.5 13.1 0.22 11.9 1.2 3.2 4 0 0 4 4 3 0 Zinc-finger double-stranded RNA-binding zf-C2HE PF16278.5 OAG44762.1 - 0.11 13.0 16.4 0.11 12.9 1.7 3.3 1 1 2 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger zf-BED PF02892.15 OAG44762.1 - 0.13 12.3 18.4 0.27 11.3 0.4 4.2 2 2 1 3 3 3 0 BED zinc finger PyrI_C PF02748.15 OAG44762.1 - 0.14 12.1 0.1 0.14 12.1 0.1 2.6 3 1 0 3 3 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_9 PF16293.5 OAG44762.1 - 0.27 11.1 4.2 0.85 9.5 0.1 2.3 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) zinc_ribbon_4 PF13717.6 OAG44762.1 - 0.91 9.5 0.1 0.91 9.5 0.1 3.5 4 0 0 4 4 3 0 zinc-ribbon domain DUF629 PF04780.12 OAG44762.1 - 1.1 7.7 10.3 0.72 8.3 2.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF629) Sprouty PF05210.13 OAG44762.1 - 1.3 9.4 8.0 19 5.7 0.5 3.1 3 0 0 3 3 3 0 Sprouty protein (Spry) TF_Zn_Ribbon PF08271.12 OAG44762.1 - 1.8 8.2 6.2 5.3 6.6 0.1 2.9 2 1 0 2 2 2 0 TFIIB zinc-binding zf-CHY PF05495.12 OAG44762.1 - 1.8 9.1 10.6 0.38 11.3 6.3 2.0 1 1 1 2 2 2 0 CHY zinc finger zinc_ribbon_5 PF13719.6 OAG44762.1 - 2.9 7.7 9.7 8 6.3 0.1 3.5 4 0 0 4 4 4 0 zinc-ribbon domain zf-C2H2_12 PF18658.1 OAG44762.1 - 3.3 7.3 8.6 2.2 7.9 2.7 2.4 2 0 0 2 2 2 0 Zinc-finger C2H2-type zinc-ribbons_6 PF07191.12 OAG44762.1 - 4.7 7.3 10.9 7.9 6.5 6.4 2.5 2 1 0 2 2 2 0 zinc-ribbons HypA PF01155.19 OAG44762.1 - 5.4 7.1 7.8 85 3.2 7.8 2.3 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA RRM_1 PF00076.22 OAG44763.1 - 2.6e-26 91.2 0.5 2.9e-12 46.2 0.2 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OAG44763.1 - 3.8e-06 26.7 0.0 0.0089 15.9 0.1 2.2 2 0 0 2 2 2 2 Occluded RNA-recognition motif RRM_5 PF13893.6 OAG44763.1 - 9.5e-05 22.0 0.0 0.0018 17.8 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4523 PF15023.6 OAG44763.1 - 0.0019 18.0 0.0 0.0047 16.8 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF4523) DUF1027 PF06265.11 OAG44763.1 - 0.048 13.6 0.0 0.084 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1027) ATP-synt_D PF01813.17 OAG44764.1 - 2.2e-71 239.8 1.3 2.7e-71 239.5 1.3 1.1 1 0 0 1 1 1 1 ATP synthase subunit D PHM7_cyt PF14703.6 OAG44764.1 - 2.5 8.3 5.2 1.3 9.2 1.0 2.2 1 1 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter TPR_14 PF13428.6 OAG44765.1 - 8.6e-18 63.5 10.5 0.066 14.1 0.0 11.5 12 0 0 12 12 11 2 Tetratricopeptide repeat Suf PF05843.14 OAG44765.1 - 1.8e-14 54.4 6.6 0.0002 21.4 0.1 5.8 4 1 2 6 6 6 3 Suppressor of forked protein (Suf) TPR_15 PF13429.6 OAG44765.1 - 1.1e-07 31.4 1.7 6.8e-05 22.2 0.0 4.1 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 OAG44765.1 - 2.1e-07 30.6 1.0 0.11 12.7 0.0 6.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 OAG44765.1 - 6.5e-06 25.9 5.7 5.6 7.3 0.1 6.9 7 0 0 7 7 7 2 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 OAG44765.1 - 1.6e-05 24.9 9.2 0.4 10.7 0.0 6.7 7 1 1 8 8 8 2 Mad3/BUB1 homology region 1 TPR_12 PF13424.6 OAG44765.1 - 4.6e-05 23.6 2.6 7.1 7.0 0.1 6.1 6 1 0 6 6 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 OAG44765.1 - 0.0002 21.5 4.7 0.19 12.2 0.0 6.2 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_19 PF14559.6 OAG44765.1 - 0.00072 20.0 5.0 0.065 13.8 0.1 5.3 5 1 1 6 6 6 1 Tetratricopeptide repeat NRDE-2 PF08424.10 OAG44765.1 - 0.0012 18.1 9.7 0.1 11.7 0.9 5.7 2 2 4 6 6 6 1 NRDE-2, necessary for RNA interference RPN7 PF10602.9 OAG44765.1 - 0.0015 18.2 0.1 0.042 13.6 0.1 3.1 3 1 0 3 3 3 1 26S proteasome subunit RPN7 GHL15 PF14885.6 OAG44765.1 - 0.065 13.2 0.1 0.93 9.4 0.0 2.5 2 0 0 2 2 2 0 Hypothetical glycosyl hydrolase family 15 TPR_6 PF13174.6 OAG44765.1 - 0.16 12.7 6.5 13 6.7 0.0 5.8 6 0 0 6 6 5 0 Tetratricopeptide repeat HAT PF02184.16 OAG44765.1 - 0.22 11.5 13.2 3.9 7.5 0.0 5.9 6 0 0 6 6 6 0 HAT (Half-A-TPR) repeat TPR_4 PF07721.14 OAG44765.1 - 3.2 8.6 14.2 1.9 9.3 0.0 4.9 5 0 0 5 5 4 0 Tetratricopeptide repeat Aldedh PF00171.22 OAG44766.1 - 8.7e-121 403.6 0.0 1e-120 403.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family TPR_12 PF13424.6 OAG44767.1 - 2.4e-06 27.7 0.3 0.027 14.8 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 OAG44767.1 - 0.13 12.2 0.1 5.2 7.1 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 OAG44767.1 - 0.14 13.0 1.5 32 5.7 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Cpn60_TCP1 PF00118.24 OAG44768.1 - 4.8e-151 503.7 18.9 5.4e-151 503.6 18.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Mei5 PF10376.9 OAG44768.1 - 0.044 13.6 1.5 1.9 8.3 0.1 2.4 2 0 0 2 2 2 0 Double-strand recombination repair protein DUF3328 PF11807.8 OAG44769.1 - 2.2e-46 158.4 1.6 9.7e-44 149.8 1.6 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.8 OAG44770.1 - 0.26 11.0 3.1 1.9 8.2 3.1 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3328) GRDP-like PF07173.12 OAG44771.1 - 0.01 16.5 1.4 0.24 12.0 0.1 2.7 2 1 0 2 2 2 1 Glycine-rich domain-containing protein-like DUF3328 PF11807.8 OAG44772.1 - 7.1e-30 104.4 0.0 2.1e-29 102.9 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) Fasciclin PF02469.22 OAG44773.1 - 1.2e-25 90.2 0.0 6.7e-16 58.7 0.0 2.9 2 1 0 2 2 2 2 Fasciclin domain DUF2688 PF10892.8 OAG44774.1 - 0.067 12.7 0.8 0.15 11.5 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2688) bZIP_1 PF00170.21 OAG44774.1 - 0.12 12.5 8.1 0.45 10.6 8.1 2.0 1 0 0 1 1 1 0 bZIP transcription factor Trefoil PF00088.18 OAG44775.1 - 0.088 12.7 0.8 0.088 12.7 0.8 1.9 2 0 0 2 2 2 0 Trefoil (P-type) domain DUF3328 PF11807.8 OAG44776.1 - 2e-29 103.0 3.1 5e-26 91.8 0.1 2.6 1 1 2 3 3 3 2 Domain of unknown function (DUF3328) Nuc_deoxyri_tr2 PF15891.5 OAG44777.1 - 4.5e-38 129.9 0.0 5.6e-38 129.6 0.0 1.1 1 0 0 1 1 1 1 Nucleoside 2-deoxyribosyltransferase like Nuc_deoxyrib_tr PF05014.15 OAG44777.1 - 0.018 15.0 0.0 0.02 14.9 0.0 1.2 1 0 0 1 1 1 0 Nucleoside 2-deoxyribosyltransferase PHO4 PF01384.20 OAG44779.1 - 3.9e-102 341.8 16.0 4.5e-102 341.6 16.0 1.0 1 0 0 1 1 1 1 Phosphate transporter family ProRS-C_1 PF09180.11 OAG44780.1 - 4.3e-23 81.3 0.4 9.6e-23 80.2 0.2 1.7 2 0 0 2 2 2 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.25 OAG44780.1 - 2e-19 70.3 0.0 3.3e-19 69.6 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 OAG44780.1 - 7.8e-13 48.4 0.0 2.3e-12 46.9 0.0 1.9 1 0 0 1 1 1 1 Anticodon binding domain DUF116 PF01976.17 OAG44780.1 - 0.18 11.3 0.0 0.31 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF116 Acetyltransf_1 PF00583.25 OAG44781.1 - 2.8e-07 30.8 0.0 4.8e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family DUF5590 PF17881.1 OAG44781.1 - 0.017 15.2 0.0 0.041 14.0 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5590) Acetyltransf_10 PF13673.7 OAG44781.1 - 0.041 13.8 0.0 0.075 13.0 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OAG44781.1 - 0.044 14.2 0.0 0.094 13.1 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Pho86 PF11124.8 OAG44781.1 - 0.15 11.5 0.1 0.28 10.6 0.1 1.3 1 0 0 1 1 1 0 Inorganic phosphate transporter Pho86 Metallophos PF00149.28 OAG44782.1 - 4e-32 112.4 0.0 1.6e-23 84.2 0.0 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase COA2 PF17051.5 OAG44783.1 - 0.02 14.9 1.0 0.039 14.0 0.1 2.0 2 1 0 2 2 2 0 Cytochrome C oxidase assembly factor 2 BNIP2 PF12496.8 OAG44784.1 - 0.1 13.0 1.8 0.25 11.8 1.8 1.6 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 Ndc1_Nup PF09531.10 OAG44784.1 - 0.41 9.3 1.3 0.59 8.8 1.3 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Methyltransf_33 PF10017.9 OAG44785.1 - 2e-82 276.8 2.5 3.5e-82 276.0 2.5 1.3 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.16 OAG44785.1 - 6.3e-18 65.3 1.8 2.5e-09 37.1 0.2 2.3 2 0 0 2 2 2 2 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.7 OAG44785.1 - 0.0018 18.8 0.7 0.0083 16.6 0.2 2.4 2 0 0 2 2 2 1 DinB superfamily Methyltransf_12 PF08242.12 OAG44785.1 - 0.085 13.6 0.0 0.21 12.4 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain RhoGEF PF00621.20 OAG44786.1 - 3.6e-12 46.9 0.1 7e-12 46.0 0.1 1.4 1 0 0 1 1 1 1 RhoGEF domain DUF3507 PF12015.8 OAG44786.1 - 6e-06 26.1 0.0 1.1e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3507) DivIC PF04977.15 OAG44786.1 - 0.2 11.5 0.7 0.71 9.7 0.9 1.8 2 0 0 2 2 2 0 Septum formation initiator YabA PF06156.13 OAG44786.1 - 0.23 12.1 0.9 0.98 10.1 0.2 2.3 2 0 0 2 2 2 0 Initiation control protein YabA WD40 PF00400.32 OAG44787.1 - 6.8e-17 61.5 2.2 9.3e-05 23.1 0.6 6.6 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG44787.1 - 4.9e-07 29.9 0.0 0.0002 21.6 0.0 4.0 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OAG44787.1 - 0.0022 16.7 0.1 0.0035 16.1 0.1 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 S1 PF00575.23 OAG44788.1 - 1.2e-77 256.3 36.7 8.6e-15 54.8 3.3 12.5 12 0 0 12 12 12 10 S1 RNA binding domain TPR_14 PF13428.6 OAG44788.1 - 2.3e-08 34.1 0.4 0.0034 18.1 0.0 4.4 3 1 2 5 5 4 2 Tetratricopeptide repeat Suf PF05843.14 OAG44788.1 - 3.3e-08 33.9 13.0 0.0015 18.6 0.1 4.2 3 1 2 5 5 4 3 Suppressor of forked protein (Suf) TPR_19 PF14559.6 OAG44788.1 - 2e-06 28.2 0.1 0.13 12.8 0.0 3.4 4 0 0 4 4 4 2 Tetratricopeptide repeat RNase_II_C_S1 PF18614.1 OAG44788.1 - 0.00037 20.4 15.5 0.32 11.0 0.1 6.4 7 1 0 7 7 7 2 RNase II-type exonuclease C-terminal S1 domain TPR_12 PF13424.6 OAG44788.1 - 0.00047 20.4 0.8 1.9 8.9 0.7 3.4 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 OAG44788.1 - 0.006 17.2 0.0 0.55 10.9 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat PPR PF01535.20 OAG44788.1 - 0.0083 16.3 0.0 0.029 14.6 0.0 2.0 1 0 0 1 1 1 1 PPR repeat TPR_7 PF13176.6 OAG44788.1 - 0.011 15.7 0.2 0.1 12.6 0.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat PCB_OB PF17092.5 OAG44788.1 - 0.02 15.6 11.9 3.4 8.4 0.1 7.5 6 2 2 9 9 9 0 Penicillin-binding protein OB-like domain S1_2 PF13509.6 OAG44788.1 - 0.031 14.3 0.3 1.9 8.6 0.0 3.9 4 0 0 4 4 4 0 S1 domain Wzy_C_2 PF11846.8 OAG44788.1 - 0.065 13.2 0.0 0.19 11.6 0.0 1.8 1 0 0 1 1 1 0 Virulence factor membrane-bound polymerase, C-terminal TPR_17 PF13431.6 OAG44788.1 - 0.066 13.6 0.0 11 6.7 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_15 PF13429.6 OAG44788.1 - 0.19 10.9 1.3 0.91 8.7 0.3 2.1 2 1 1 3 3 3 0 Tetratricopeptide repeat DNA_ligase_A_M PF01068.21 OAG44790.1 - 1.8e-47 161.7 0.0 4.8e-47 160.3 0.0 1.8 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 OAG44790.1 - 5.3e-43 147.3 0.2 2.4e-42 145.2 0.0 2.3 3 0 0 3 3 3 1 DNA ligase N terminus BRCT_2 PF16589.5 OAG44790.1 - 7.2e-17 61.6 1.1 3.2e-12 46.7 0.0 2.9 3 0 0 3 3 3 2 BRCT domain, a BRCA1 C-terminus domain RNA_ligase PF09414.10 OAG44790.1 - 1.2e-15 58.2 0.0 2.4e-15 57.2 0.0 1.6 1 0 0 1 1 1 1 RNA ligase DNA_ligase_A_C PF04679.15 OAG44790.1 - 3.8e-13 49.9 0.3 3.7e-11 43.5 0.0 3.6 2 1 1 3 3 3 1 ATP dependent DNA ligase C terminal region BRCT PF00533.26 OAG44790.1 - 5.4e-06 26.7 1.6 0.00011 22.5 0.0 2.8 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain DNA_ligase_IV PF11411.8 OAG44790.1 - 0.0001 22.4 0.0 0.00028 20.9 0.0 1.8 1 0 0 1 1 1 1 DNA ligase IV LIG3_BRCT PF16759.5 OAG44790.1 - 0.039 14.2 0.3 5.3 7.4 0.2 2.8 2 0 0 2 2 2 0 DNA ligase 3 BRCT domain RTT107_BRCT_5 PF16770.5 OAG44790.1 - 0.13 12.2 0.0 13 5.8 0.0 2.6 2 0 0 2 2 2 0 Regulator of Ty1 transposition protein 107 BRCT domain EF-hand_4 PF12763.7 OAG44791.1 - 0.0044 17.0 0.0 0.009 16.0 0.0 1.5 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand PRAS PF15798.5 OAG44792.1 - 0.37 11.4 6.4 0.59 10.7 5.9 1.6 1 1 0 1 1 1 0 Proline-rich AKT1 substrate 1 CPSase_L_D2 PF02786.17 OAG44793.1 - 2e-113 377.1 0.3 1.5e-83 279.5 0.0 2.4 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 OAG44793.1 - 3e-47 159.6 0.0 6.2e-47 158.6 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 OAG44793.1 - 1.2e-46 158.9 0.0 4.5e-46 157.0 0.0 2.0 2 0 0 2 2 2 1 Glutamine amidotransferase class-I OTCace_N PF02729.21 OAG44793.1 - 2e-44 151.2 0.0 4.8e-44 150.0 0.0 1.7 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_D3 PF02787.19 OAG44793.1 - 6.4e-40 136.3 0.0 1.5e-39 135.1 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.24 OAG44793.1 - 1.1e-29 103.6 0.0 2.8e-29 102.2 0.0 1.8 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain MGS PF02142.22 OAG44793.1 - 2.5e-20 72.5 0.0 7.4e-20 70.9 0.0 1.9 1 0 0 1 1 1 1 MGS-like domain Dala_Dala_lig_C PF07478.13 OAG44793.1 - 3.1e-17 62.8 0.2 1.4e-08 34.5 0.1 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 OAG44793.1 - 8.4e-16 58.0 0.1 2.2e-07 30.6 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 OAG44793.1 - 1.7e-09 37.5 0.0 0.00018 21.3 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.14 OAG44793.1 - 2.8e-05 24.2 0.3 0.083 12.9 0.1 2.7 2 0 0 2 2 2 2 ATP-grasp domain Peptidase_C26 PF07722.13 OAG44793.1 - 6.3e-05 22.8 0.8 0.0039 17.0 0.1 2.8 2 1 0 2 2 2 1 Peptidase C26 RimK PF08443.11 OAG44793.1 - 0.00041 20.0 0.0 0.16 11.6 0.0 2.6 2 0 0 2 2 2 2 RimK-like ATP-grasp domain DJ-1_PfpI PF01965.24 OAG44793.1 - 0.0013 18.6 0.3 0.12 12.1 0.0 3.5 4 0 0 4 4 4 1 DJ-1/PfpI family ID PF18543.1 OAG44793.1 - 0.009 16.0 0.0 0.35 10.9 0.0 2.8 2 0 0 2 2 2 1 Intracellular delivery domain GPP34 PF05719.11 OAG44794.1 - 0.14 12.2 0.8 0.4 10.7 0.8 1.7 1 0 0 1 1 1 0 Golgi phosphoprotein 3 (GPP34) Synaptobrevin PF00957.21 OAG44795.1 - 8e-32 108.9 0.0 1.1e-31 108.5 0.0 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 OAG44795.1 - 1e-28 99.1 0.2 1.9e-28 98.3 0.2 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain RRM_1 PF00076.22 OAG44797.1 - 8.5e-14 51.1 0.0 1.5e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 OAG44797.1 - 3.6e-07 30.6 2.2 3.6e-07 30.6 2.2 2.8 2 2 0 2 2 2 1 C-terminal duplication domain of Friend of PRMT1 RRM_occluded PF16842.5 OAG44797.1 - 4.9e-05 23.1 0.0 8.3e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Occluded RNA-recognition motif RRM_7 PF16367.5 OAG44797.1 - 0.07 13.3 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif Snf7 PF03357.21 OAG44798.1 - 3.2e-26 92.0 8.9 3.2e-26 92.0 8.9 1.8 1 1 1 2 2 2 1 Snf7 Gon7 PF08738.10 OAG44798.1 - 0.022 14.8 2.9 0.055 13.6 0.8 2.4 2 0 0 2 2 2 0 Gon7 family V_ATPase_I PF01496.19 OAG44798.1 - 2.2 6.1 4.7 2.3 6.0 4.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CS PF04969.16 OAG44799.1 - 2.9e-05 25.0 0.1 4.6e-05 24.4 0.1 1.2 1 0 0 1 1 1 1 CS domain LtrA PF06772.11 OAG44800.1 - 3.6e-34 118.5 32.2 4.5e-34 118.2 32.2 1.1 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) DUF1129 PF06570.11 OAG44800.1 - 0.017 14.6 5.0 0.037 13.5 5.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) DFRP_C PF16543.5 OAG44802.1 - 3.6e-26 91.5 8.1 3.6e-26 91.5 8.1 4.4 3 2 1 4 4 4 1 DRG Family Regulatory Proteins, Tma46 zf-CCCH PF00642.24 OAG44802.1 - 1.2e-06 28.2 2.9 1.2e-06 28.2 2.9 2.6 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 OAG44802.1 - 7.9e-05 22.4 12.4 0.00064 19.5 3.5 3.3 3 0 0 3 3 3 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 OAG44802.1 - 0.00055 19.9 9.6 0.00055 19.9 9.6 3.3 3 0 0 3 3 3 1 Zinc finger domain Torus PF16131.5 OAG44802.1 - 0.00093 19.9 18.7 0.0011 19.7 7.3 3.4 2 1 1 3 3 3 2 Torus domain zf-CCCH_3 PF15663.5 OAG44802.1 - 0.032 14.5 5.1 0.25 11.6 0.2 2.8 3 0 0 3 3 3 0 Zinc-finger containing family zf-CCCH_2 PF14608.6 OAG44802.1 - 0.063 13.8 15.4 0.12 12.9 5.8 2.9 2 1 0 2 2 2 0 RNA-binding, Nab2-type zinc finger MAS20 PF02064.15 OAG44802.1 - 0.34 11.0 0.1 0.34 11.0 0.1 3.7 4 0 0 4 4 4 0 MAS20 protein import receptor MAS20 PF02064.15 OAG44804.1 - 1.2e-43 148.3 0.2 1.4e-43 148.1 0.2 1.0 1 0 0 1 1 1 1 MAS20 protein import receptor PMC2NT PF08066.12 OAG44804.1 - 0.19 12.5 0.0 0.27 11.9 0.0 1.2 1 0 0 1 1 1 0 PMC2NT (NUC016) domain Cu_amine_oxid PF01179.20 OAG44805.1 - 4.1e-162 539.8 0.0 5.2e-162 539.4 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.16 OAG44805.1 - 1.2e-07 31.8 0.0 2.5e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.16 OAG44805.1 - 0.002 18.5 0.0 0.0046 17.3 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Aldedh PF00171.22 OAG44806.1 - 1.3e-178 594.3 0.7 1.5e-178 594.1 0.7 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Hemerythrin PF01814.23 OAG44807.1 - 3.8e-09 37.2 2.4 7.2e-09 36.4 2.3 1.5 1 1 0 1 1 1 1 Hemerythrin HHE cation binding domain DUF775 PF05603.12 OAG44808.1 - 3.7e-64 215.9 0.1 4.2e-64 215.8 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) Kdo PF06293.14 OAG44810.1 - 5.3e-05 22.7 0.0 9.4e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OAG44810.1 - 5.7e-05 22.8 0.0 9.3e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 OAG44810.1 - 0.00011 22.3 0.1 0.0015 18.5 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.25 OAG44810.1 - 0.0017 17.8 0.0 0.0025 17.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 OAG44810.1 - 0.083 11.6 0.1 0.12 11.1 0.1 1.2 1 0 0 1 1 1 0 Fungal protein kinase NUDIX PF00293.28 OAG44811.1 - 2.2e-12 47.1 0.0 4.3e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain DUF4743 PF15916.5 OAG44811.1 - 9.9e-11 41.7 0.0 1.8e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4743) RNA_pol_Rpb8 PF03870.15 OAG44812.1 - 8.3e-44 149.2 0.2 9.3e-44 149.0 0.2 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 RNA_pol_RpbG PF16992.5 OAG44812.1 - 0.00019 21.5 0.2 0.054 13.5 0.1 2.1 1 1 1 2 2 2 2 DNA-directed RNA polymerase, subunit G PAXNEB PF05625.11 OAG44813.1 - 1.9e-108 362.9 0.0 2.2e-108 362.7 0.0 1.0 1 0 0 1 1 1 1 PAXNEB protein tRNA_int_endo PF01974.17 OAG44814.1 - 1.6e-14 53.8 0.0 3.1e-14 52.8 0.0 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain UPF0086 PF01868.16 OAG44815.1 - 3.9e-27 94.0 0.0 6.1e-27 93.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function UPF0086 TRI12 PF06609.13 OAG44816.1 - 1.6e-68 231.7 26.8 2.1e-68 231.3 26.8 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG44816.1 - 9.3e-17 61.0 41.0 2e-16 59.9 41.0 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Cupin_2 PF07883.11 OAG44817.1 - 1.4e-16 59.9 1.7 5.7e-09 35.6 0.5 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_1 PF00190.22 OAG44817.1 - 1.1e-05 25.1 0.3 0.0073 15.9 0.0 3.0 2 1 1 3 3 3 2 Cupin Cupin_6 PF12852.7 OAG44817.1 - 4.5e-05 23.3 0.6 0.0062 16.3 0.1 2.1 2 0 0 2 2 2 2 Cupin AraC_binding PF02311.19 OAG44817.1 - 8.6e-05 22.5 1.1 0.0049 16.8 0.6 2.4 2 1 0 2 2 2 1 AraC-like ligand binding domain MannoseP_isomer PF01050.18 OAG44817.1 - 0.015 15.2 0.1 0.75 9.7 0.0 2.2 2 0 0 2 2 2 0 Mannose-6-phosphate isomerase DMSP_lyase PF16867.5 OAG44817.1 - 0.036 13.7 0.0 0.074 12.7 0.0 1.4 1 0 0 1 1 1 0 Dimethlysulfonioproprionate lyase TRI12 PF06609.13 OAG44818.1 - 8.8e-73 245.7 28.2 1.1e-72 245.4 28.2 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG44818.1 - 2.1e-27 96.0 47.2 2.1e-27 96.0 47.2 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG44818.1 - 5.4e-10 38.7 7.3 5.4e-10 38.7 7.3 3.1 3 0 0 3 3 3 2 Sugar (and other) transporter Pkinase PF00069.25 OAG44819.1 - 1.1e-08 34.8 0.0 2e-08 33.9 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG44819.1 - 4.6e-05 22.8 0.0 0.00021 20.7 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OAG44819.1 - 0.0013 18.7 0.1 0.002 18.1 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family PIP49_C PF12260.8 OAG44819.1 - 0.05 13.2 0.0 0.098 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 Kdo PF06293.14 OAG44819.1 - 0.058 12.7 0.1 0.097 12.0 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ten1_2 PF15490.6 OAG44820.1 - 0.041 13.6 0.1 0.086 12.6 0.1 1.5 1 0 0 1 1 1 0 Telomere-capping, CST complex subunit FPN1 PF06963.12 OAG44821.1 - 1.9e-69 234.3 7.7 2.5e-69 233.9 7.7 1.0 1 0 0 1 1 1 1 Ferroportin1 (FPN1) Cyclase PF04199.13 OAG44822.1 - 1.3e-12 48.1 0.0 1.7e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase Fungal_trans PF04082.18 OAG44823.1 - 2e-20 73.0 2.4 3.3e-20 72.2 2.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG44823.1 - 4.5e-06 26.7 3.1 4.5e-06 26.7 3.1 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain OB_RNB PF08206.11 OAG44824.1 - 0.29 10.8 3.4 0.74 9.5 3.4 1.8 1 0 0 1 1 1 0 Ribonuclease B OB domain MFS_1 PF07690.16 OAG44825.1 - 4.1e-09 35.8 19.6 4.1e-09 35.8 19.6 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 OAG44825.1 - 6.2e-06 26.0 5.0 2e-05 24.4 5.0 1.9 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 GlpM PF06942.12 OAG44825.1 - 2.2 8.7 5.7 0.51 10.8 0.7 2.5 3 0 0 3 3 3 0 GlpM protein Polysacc_deac_1 PF01522.21 OAG44826.1 - 9.9e-21 73.9 0.0 1.7e-20 73.2 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 OAG44826.1 - 3.6e-11 43.1 0.3 1.2e-10 41.4 0.3 1.8 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) Glyco_hydro_57 PF03065.15 OAG44826.1 - 0.0081 15.4 0.1 0.043 13.0 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 57 SAMP PF05924.11 OAG44826.1 - 0.51 9.7 1.5 0.98 8.8 1.5 1.5 1 0 0 1 1 1 0 SAMP Motif Zn_clus PF00172.18 OAG44827.1 - 4e-07 30.0 11.0 8.1e-07 29.1 11.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MIT PF04212.18 OAG44827.1 - 0.14 12.2 0.1 0.43 10.7 0.1 1.8 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain WD40 PF00400.32 OAG44828.1 - 2.3e-13 50.4 16.9 0.0052 17.6 0.1 6.7 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG44828.1 - 4.1e-07 30.2 0.1 0.17 12.2 0.0 4.1 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Pantoate_ligase PF02569.15 OAG44829.1 - 4.5e-83 278.5 0.0 5.4e-83 278.3 0.0 1.1 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase DEAD PF00270.29 OAG44830.1 - 6.2e-43 146.6 0.1 1e-42 145.9 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.6 OAG44830.1 - 6.3e-20 71.2 0.1 1.5e-19 70.0 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.31 OAG44830.1 - 6.8e-20 71.5 0.0 5.2e-19 68.6 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAG44830.1 - 1.4e-06 28.4 0.0 2.8e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 OAG44830.1 - 0.021 14.0 0.0 0.037 13.2 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase CMS1 PF14617.6 OAG44830.1 - 0.1 11.9 0.2 4.9 6.4 0.0 2.5 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit WD40 PF00400.32 OAG44831.1 - 6.8e-12 45.7 4.7 0.016 16.1 1.0 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG44831.1 - 1.3e-05 25.4 0.0 9.6 6.6 0.0 4.8 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain LpxI_C PF06230.11 OAG44831.1 - 0.082 12.8 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 LpxI C-terminal domain Rib_5-P_isom_A PF06026.14 OAG44832.1 - 1.7e-41 141.7 0.0 3e-41 140.9 0.0 1.3 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) ThiF PF00899.21 OAG44833.1 - 4.2e-13 49.2 0.0 1.1e-12 47.9 0.0 1.7 1 1 0 1 1 1 1 ThiF family LRR_4 PF12799.7 OAG44834.1 - 1.4e-35 120.7 45.9 8.2e-05 22.9 1.7 11.0 7 2 3 11 11 11 10 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OAG44834.1 - 8.7e-33 111.9 44.8 1.8e-08 34.0 2.8 9.9 7 1 5 12 12 12 10 Leucine rich repeat LRR_1 PF00560.33 OAG44834.1 - 9.6e-11 40.7 38.8 0.83 10.4 0.1 15.0 16 2 0 16 16 16 5 Leucine Rich Repeat LRR_9 PF14580.6 OAG44834.1 - 1.3e-10 41.1 13.8 0.0017 17.9 0.3 4.8 2 1 2 4 4 4 4 Leucine-rich repeat LRR_6 PF13516.6 OAG44834.1 - 2e-08 33.6 38.4 5.1 7.4 0.7 14.0 15 0 0 15 15 15 5 Leucine Rich repeat LRR_5 PF13306.6 OAG44834.1 - 0.08 12.9 0.0 4.1 7.4 0.0 2.6 2 0 0 2 2 2 0 BspA type Leucine rich repeat region (6 copies) CCDC-167 PF15188.6 OAG44835.1 - 4.4 7.7 10.9 0.67 10.3 6.6 1.8 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 DUF3347 PF11827.8 OAG44835.1 - 4.9 7.3 6.3 9.3 6.4 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3347) YabA PF06156.13 OAG44835.1 - 7.3 7.3 9.4 1.3 9.7 2.5 2.3 2 0 0 2 2 2 0 Initiation control protein YabA DUF5320 PF17253.2 OAG44835.1 - 9.2 7.4 8.1 2.1 9.5 0.6 3.0 2 1 1 3 3 3 0 Family of unknown function (DUF5320) FUSC PF04632.12 OAG44835.1 - 9.8 4.6 10.6 16 3.9 10.6 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Ribosomal_L13e PF01294.18 OAG44836.1 - 4.2e-72 241.8 2.8 6.4e-72 241.2 2.8 1.3 1 0 0 1 1 1 1 Ribosomal protein L13e DUF3433 PF11915.8 OAG44838.1 - 1.5e-22 79.9 12.2 2.2e-12 47.3 3.7 4.7 6 0 0 6 6 6 2 Protein of unknown function (DUF3433) CrgA PF06781.12 OAG44838.1 - 0.022 14.8 0.0 1.4 9.0 0.0 3.9 3 0 0 3 3 3 0 Cell division protein CrgA DUF4834 PF16118.5 OAG44838.1 - 2.5 9.1 4.1 11 7.1 0.0 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4834) MFS_1 PF07690.16 OAG44841.1 - 8.1e-26 90.8 28.1 8.1e-26 90.8 28.1 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily GPI-anchored PF10342.9 OAG44842.1 - 1.3e-18 67.5 0.1 1.3e-18 67.5 0.1 2.2 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family FlhE PF06366.13 OAG44842.1 - 0.049 13.6 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Flagellar protein FlhE DUF3262 PF11660.8 OAG44842.1 - 0.21 12.0 0.6 0.45 10.9 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3262) FMO-like PF00743.19 OAG44844.1 - 1.3e-14 53.6 0.0 3.6e-12 45.5 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 OAG44844.1 - 9.6e-11 41.4 0.0 4.4e-09 36.0 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG44844.1 - 2.9e-08 33.3 0.0 2.7e-07 30.2 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG44844.1 - 1.6e-07 30.8 0.2 0.013 14.7 0.2 3.9 3 1 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 OAG44844.1 - 1.1e-06 28.7 0.0 5.5e-06 26.5 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 OAG44844.1 - 0.039 13.9 0.0 8 6.4 0.0 3.3 3 0 0 3 3 3 0 FAD-NAD(P)-binding Thi4 PF01946.17 OAG44844.1 - 0.13 11.5 0.1 1.1 8.5 0.0 2.1 2 0 0 2 2 2 0 Thi4 family Pyr_redox PF00070.27 OAG44844.1 - 0.14 12.7 0.0 6.4 7.4 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Abhydrolase_3 PF07859.13 OAG44845.1 - 1.1e-48 165.9 0.0 1.5e-48 165.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 OAG44845.1 - 6.1e-12 45.1 0.0 8.7e-12 44.6 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 OAG44845.1 - 0.00061 19.3 0.5 0.11 12.0 0.0 2.5 3 0 0 3 3 3 2 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 OAG44845.1 - 0.12 12.2 0.1 0.36 10.6 0.0 1.7 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Pyr_redox_2 PF07992.14 OAG44846.1 - 3.3e-18 65.9 0.0 8.4e-16 58.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 OAG44846.1 - 1.7e-14 53.2 0.0 2.8e-14 52.5 0.0 1.2 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OAG44846.1 - 9.6e-11 41.5 0.0 3.8e-08 33.0 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG44846.1 - 3e-07 29.9 0.1 6.5e-06 25.5 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 OAG44846.1 - 6.8e-07 29.4 0.1 1.8e-06 28.1 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 OAG44846.1 - 0.0002 21.4 1.1 1.5 8.7 0.5 4.2 3 1 0 3 3 3 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 OAG44846.1 - 0.0022 17.1 0.1 0.23 10.5 0.2 2.6 2 1 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.24 OAG44846.1 - 0.0034 17.0 3.2 0.67 9.5 0.4 3.3 2 1 2 4 4 4 1 FAD dependent oxidoreductase GIDA PF01134.22 OAG44846.1 - 0.02 14.0 0.0 3.9 6.4 0.0 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_2 PF00890.24 OAG44846.1 - 0.057 12.5 0.0 0.14 11.2 0.0 1.8 1 0 0 1 1 1 0 FAD binding domain Shikimate_DH PF01488.20 OAG44846.1 - 0.095 12.8 0.0 0.53 10.4 0.0 2.1 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 OAG44846.1 - 0.17 12.4 0.0 8 7.0 0.0 2.9 3 0 0 3 3 3 0 Putative NAD(P)-binding Ank_2 PF12796.7 OAG44847.1 - 3.7e-61 203.7 8.2 2.6e-10 40.7 0.1 10.3 6 2 4 11 11 11 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAG44847.1 - 6.1e-45 151.0 6.0 7.4e-10 39.2 0.0 13.0 9 5 6 15 15 15 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG44847.1 - 2.3e-44 144.2 18.0 5e-05 23.4 0.0 18.7 21 0 0 21 21 21 7 Ankyrin repeat Ank_5 PF13857.6 OAG44847.1 - 7.9e-26 89.8 10.8 0.0028 17.9 0.0 14.0 9 5 5 15 15 15 8 Ankyrin repeats (many copies) Ank PF00023.30 OAG44847.1 - 1.3e-22 79.1 23.8 0.0077 16.6 0.0 14.8 15 1 0 15 15 15 5 Ankyrin repeat Clr5 PF14420.6 OAG44847.1 - 1.9e-16 60.0 1.1 3.6e-16 59.1 1.1 1.5 1 0 0 1 1 1 1 Clr5 domain Glycos_transf_2 PF00535.26 OAG44847.1 - 0.084 12.7 0.1 3.7 7.3 0.0 2.6 2 0 0 2 2 2 0 Glycosyl transferase family 2 Phage_T7_Capsid PF05396.11 OAG44847.1 - 0.63 10.4 4.7 14 6.1 0.0 4.3 5 1 1 6 6 6 0 Phage T7 capsid assembly protein FMO-like PF00743.19 OAG44848.1 - 1.3e-12 46.9 0.1 1.1e-11 43.8 0.1 2.1 1 1 1 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OAG44848.1 - 5e-09 35.8 0.1 1.6e-07 30.9 0.0 3.0 3 1 1 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG44848.1 - 9.3e-09 34.9 0.0 6.5e-06 25.5 0.0 2.5 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 OAG44848.1 - 2.1e-06 27.2 0.0 0.00027 20.3 0.0 2.7 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAG44848.1 - 1e-05 25.5 0.0 0.023 14.7 0.0 3.3 3 1 0 3 3 3 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 OAG44848.1 - 0.00034 20.8 0.0 0.00094 19.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DUF4521 PF15021.6 OAG44848.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4521) AMP-binding PF00501.28 OAG44849.1 - 1.1e-30 106.6 0.0 4.6e-19 68.3 0.0 2.1 1 1 1 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 OAG44849.1 - 1.2e-05 26.2 0.0 2.5e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PsbR PF04725.12 OAG44849.1 - 0.011 16.1 0.1 0.023 15.1 0.1 1.5 1 0 0 1 1 1 0 Photosystem II 10 kDa polypeptide PsbR Zn_clus PF00172.18 OAG44850.1 - 3.6e-07 30.2 7.1 7.3e-07 29.2 7.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAG44850.1 - 4.3e-07 29.2 0.2 8e-07 28.3 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.25 OAG44851.1 - 5.8e-40 136.8 0.1 7.6e-40 136.5 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG44851.1 - 1.3e-38 132.9 0.0 1.9e-38 132.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG44851.1 - 0.0027 17.7 0.1 0.037 13.9 0.1 2.0 1 1 0 1 1 1 1 KR domain p450 PF00067.22 OAG44852.1 - 1.6e-74 251.4 0.0 1.9e-74 251.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 TRI12 PF06609.13 OAG44853.1 - 2.9e-83 280.3 22.5 3.7e-83 280.0 22.5 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG44853.1 - 6.6e-25 87.8 40.2 6.6e-25 87.8 40.2 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG44853.1 - 6e-08 32.0 11.7 6e-08 32.0 11.7 2.9 3 1 0 3 3 3 2 Sugar (and other) transporter CLTH PF10607.9 OAG44854.1 - 2.9e-31 108.3 0.1 3.9e-31 107.9 0.1 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 OAG44854.1 - 3.7e-09 36.2 0.0 1.1e-08 34.7 0.0 1.9 1 0 0 1 1 1 1 LisH HU-HIG PF18291.1 OAG44854.1 - 0.036 14.1 0.0 0.067 13.3 0.0 1.4 1 0 0 1 1 1 0 HU domain fused to wHTH, Ig, or Glycine-rich motif MOZ_SAS PF01853.18 OAG44855.1 - 7e-77 257.1 0.0 1.3e-76 256.3 0.0 1.4 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 OAG44855.1 - 2.6e-23 81.4 0.7 5.4e-23 80.4 0.7 1.6 1 0 0 1 1 1 1 MYST family zinc finger domain Tudor-knot PF11717.8 OAG44855.1 - 5.5e-21 74.2 0.0 1e-20 73.3 0.0 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 OAG44855.1 - 0.00097 19.5 0.0 0.002 18.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAG44855.1 - 0.0059 16.8 0.0 0.013 15.7 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family DLIC PF05783.11 OAG44855.1 - 0.18 10.6 4.2 0.31 9.8 4.2 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) WD40 PF00400.32 OAG44856.1 - 8.8e-19 67.5 4.6 0.00029 21.6 0.0 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG44856.1 - 3.9e-08 33.5 0.2 0.0016 18.7 0.1 4.7 3 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OAG44856.1 - 9.1e-08 31.2 0.9 2.9e-05 22.9 0.1 2.8 2 1 0 2 2 2 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 OAG44856.1 - 0.0048 15.7 0.0 0.21 10.3 0.0 2.5 2 1 0 2 2 2 1 Nup133 N terminal like PQQ_3 PF13570.6 OAG44856.1 - 0.11 13.0 1.0 5.6 7.6 0.0 3.8 5 0 0 5 5 5 0 PQQ-like domain DUF4241 PF14025.6 OAG44856.1 - 0.32 11.3 2.6 0.78 10.0 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF4241) DUF726 PF05277.12 OAG44857.1 - 3.3e-127 424.1 2.5 4.4e-127 423.7 2.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Glyco_tranf_2_3 PF13641.6 OAG44858.1 - 4.7e-24 85.5 0.1 6.2e-24 85.2 0.1 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 OAG44858.1 - 1.5e-06 27.8 0.0 1.4e-05 24.7 0.0 2.1 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 OAG44858.1 - 4.2e-05 23.4 0.0 0.0005 19.9 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 2 GRIP PF01465.20 OAG44859.1 - 4.1e-17 61.8 0.1 9.9e-17 60.6 0.1 1.7 1 0 0 1 1 1 1 GRIP domain CENP-F_leu_zip PF10473.9 OAG44859.1 - 9.6e-07 28.9 164.8 0.0002 21.4 14.8 11.0 3 2 8 11 11 10 4 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.6 OAG44859.1 - 2.5e-05 23.7 158.4 0.031 13.6 12.4 10.8 4 2 6 10 10 10 6 Growth-arrest specific micro-tubule binding TMF_TATA_bd PF12325.8 OAG44859.1 - 0.00022 21.4 6.3 0.00022 21.4 6.3 10.6 3 2 5 9 9 9 2 TATA element modulatory factor 1 TATA binding MscS_porin PF12795.7 OAG44859.1 - 0.0022 17.6 27.7 0.0022 17.6 27.7 9.1 3 1 5 9 9 8 4 Mechanosensitive ion channel porin domain AIP3 PF03915.13 OAG44859.1 - 0.0026 16.9 17.8 0.0026 16.9 17.8 6.0 2 1 3 5 5 3 1 Actin interacting protein 3 YscO PF07321.12 OAG44859.1 - 0.005 16.8 4.9 0.005 16.8 4.9 11.7 5 2 8 13 13 7 2 Type III secretion protein YscO Laminin_I PF06008.14 OAG44859.1 - 0.015 15.0 0.6 0.015 15.0 0.6 7.2 3 2 4 7 7 4 0 Laminin Domain I ATG16 PF08614.11 OAG44859.1 - 0.029 14.6 199.4 0.093 12.9 28.8 10.8 4 2 6 10 10 10 0 Autophagy protein 16 (ATG16) TPR_MLP1_2 PF07926.12 OAG44859.1 - 0.056 13.5 181.6 0.017 15.2 19.1 11.9 4 2 7 11 11 10 0 TPR/MLP1/MLP2-like protein DUF2563 PF10817.8 OAG44859.1 - 0.26 11.9 1.0 2.2 8.9 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2563) Nuc_N PF14448.6 OAG44859.1 - 0.33 10.8 6.1 9.6 6.2 0.1 4.2 4 0 0 4 4 4 0 Nuclease N terminal Spc7 PF08317.11 OAG44859.1 - 4.1 6.2 155.2 0.63 8.9 18.9 8.7 3 2 6 9 9 9 0 Spc7 kinetochore protein MAD PF05557.13 OAG44859.1 - 8.9 4.5 143.3 0.048 12.0 40.8 5.5 3 1 2 5 5 5 0 Mitotic checkpoint protein CALCOCO1 PF07888.11 OAG44859.1 - 9.2 5.0 164.0 0.078 11.8 39.4 6.1 4 1 2 6 6 6 0 Calcium binding and coiled-coil domain (CALCOCO1) like YL1_C PF08265.11 OAG44860.1 - 4.6e-16 58.3 1.1 8.1e-16 57.5 1.1 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Apc15p PF05841.11 OAG44860.1 - 0.0048 17.7 0.7 0.0073 17.1 0.7 1.2 1 0 0 1 1 1 1 Apc15p protein zf-HIT PF04438.16 OAG44860.1 - 0.12 12.3 0.1 0.18 11.7 0.1 1.2 1 0 0 1 1 1 0 HIT zinc finger Sulfotransfer_4 PF17784.1 OAG44861.1 - 1.4e-61 208.1 0.0 1.7e-61 207.8 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OAG44861.1 - 7.6e-07 29.7 0.6 3.9e-06 27.4 0.4 2.3 1 1 1 2 2 2 1 Sulfotransferase family NmrA PF05368.13 OAG44862.1 - 3.3e-30 105.4 0.0 4.3e-30 105.0 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAG44862.1 - 1.1e-11 45.0 0.0 3.5e-11 43.3 0.0 1.9 1 1 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 OAG44862.1 - 4.3e-07 30.3 0.0 3e-06 27.5 0.1 2.1 2 1 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 OAG44862.1 - 5.2e-07 29.4 0.0 0.00015 21.3 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 OAG44862.1 - 4.1e-06 27.2 0.0 1.6e-05 25.3 0.0 1.9 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 OAG44862.1 - 3.1e-05 23.1 0.1 4.6e-05 22.6 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 OAG44862.1 - 0.0018 17.5 0.1 0.0027 16.9 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DapB_N PF01113.20 OAG44862.1 - 0.0022 18.1 0.1 0.0064 16.6 0.0 1.8 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus KR PF08659.10 OAG44862.1 - 0.0031 17.5 0.0 0.0053 16.7 0.0 1.3 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 OAG44862.1 - 0.0032 16.9 0.0 0.061 12.7 0.0 2.0 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 OAG44862.1 - 0.061 12.8 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase NAD_binding_4 PF07993.12 OAG44862.1 - 0.068 12.3 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein DXP_reductoisom PF02670.16 OAG44862.1 - 0.15 12.8 0.1 0.89 10.3 0.1 2.2 1 1 1 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Actin PF00022.19 OAG44863.1 - 1.4e-47 162.2 0.0 2.5e-25 88.9 0.0 2.3 2 0 0 2 2 2 2 Actin bZIP_1 PF00170.21 OAG44864.1 - 1.7e-08 34.4 6.9 5.1e-08 32.9 6.9 1.7 1 1 0 1 1 1 1 bZIP transcription factor Imm32 PF15566.6 OAG44864.1 - 0.18 11.6 0.1 1.8 8.5 0.0 2.2 2 0 0 2 2 2 0 Immunity protein 32 bZIP_2 PF07716.15 OAG44864.1 - 0.18 11.9 9.7 1.6 8.9 5.6 2.2 1 1 1 2 2 2 0 Basic region leucine zipper Peptidase_S10 PF00450.22 OAG44865.1 - 3.2e-77 260.7 0.1 4.5e-77 260.2 0.1 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase RNA_pol_A_bac PF01000.26 OAG44866.1 - 1.9e-28 99.1 0.0 2.8e-28 98.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 OAG44866.1 - 4.7e-14 51.6 0.0 6.2e-14 51.2 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Transketolase_N PF00456.21 OAG44867.1 - 9.8e-154 511.3 0.0 1.3e-153 510.9 0.0 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 OAG44867.1 - 4.5e-45 153.5 0.0 8e-45 152.7 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 OAG44867.1 - 1.1e-11 44.7 0.0 2.5e-11 43.5 0.0 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 OAG44867.1 - 5.9e-05 22.4 0.0 0.00011 21.5 0.0 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Beta_elim_lyase PF01212.21 OAG44867.1 - 0.01 15.2 0.0 0.017 14.4 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase E1_dh PF00676.20 OAG44867.1 - 0.017 14.1 0.1 0.025 13.5 0.1 1.2 1 0 0 1 1 1 0 Dehydrogenase E1 component zf-RING_13 PF17977.1 OAG44867.1 - 0.1 12.8 0.4 0.34 11.1 0.1 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain PFO_beta_C PF12367.8 OAG44867.1 - 0.15 12.2 0.1 1.1 9.4 0.0 2.5 2 0 0 2 2 2 0 Pyruvate ferredoxin oxidoreductase beta subunit C terminal adh_short PF00106.25 OAG44868.1 - 6.9e-33 113.8 0.0 8.6e-33 113.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG44868.1 - 4.9e-24 85.2 0.1 6.3e-24 84.8 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG44868.1 - 1e-07 32.0 0.3 1.9e-07 31.2 0.3 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG44868.1 - 4.1e-06 26.4 0.0 3.1e-05 23.5 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 OAG44868.1 - 2.2e-05 24.4 0.1 2.8e-05 24.1 0.1 1.4 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 OAG44868.1 - 0.013 15.1 0.1 0.022 14.3 0.1 1.3 1 0 0 1 1 1 0 NmrA-like family 3Beta_HSD PF01073.19 OAG44868.1 - 0.024 13.6 0.0 0.035 13.1 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 OAG44868.1 - 0.054 12.9 0.0 0.13 11.6 0.0 1.6 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 OAG44868.1 - 0.087 11.9 0.0 0.16 11.1 0.0 1.4 2 0 0 2 2 2 0 RmlD substrate binding domain RRM_1 PF00076.22 OAG44869.1 - 2.8e-83 273.7 3.6 1.8e-21 75.8 0.3 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 OAG44869.1 - 1.2e-30 105.5 0.6 6e-30 103.2 0.5 2.3 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 OAG44869.1 - 5.6e-14 51.8 0.2 0.0082 15.7 0.0 5.3 2 1 3 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OAG44869.1 - 2.7e-07 30.3 0.1 5e-05 23.1 0.0 3.3 4 0 0 4 4 4 1 Occluded RNA-recognition motif Limkain-b1 PF11608.8 OAG44869.1 - 8.9e-05 22.5 1.0 4.1 7.5 0.0 4.5 4 0 0 4 4 4 1 Limkain b1 RRM_7 PF16367.5 OAG44869.1 - 0.00012 22.1 0.1 2.3 8.4 0.0 5.1 5 1 0 5 5 5 1 RNA recognition motif YflT PF11181.8 OAG44869.1 - 0.00025 21.5 5.0 0.01 16.4 0.8 2.8 3 0 0 3 3 3 1 Heat induced stress protein YflT Nup35_RRM_2 PF14605.6 OAG44869.1 - 0.00031 20.7 0.2 19 5.4 0.0 4.2 4 0 0 4 4 4 0 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 OAG44869.1 - 0.02 15.0 8.8 3.5 7.7 0.1 4.9 5 0 0 5 5 5 0 RNA binding motif PhetRS_B1 PF18262.1 OAG44869.1 - 0.056 13.7 0.2 6 7.2 0.0 3.2 3 0 0 3 3 3 0 Phe-tRNA synthetase beta subunit B1 domain OB_RNB PF08206.11 OAG44869.1 - 0.14 11.9 2.0 17 5.1 0.0 3.5 3 0 0 3 3 3 0 Ribonuclease B OB domain DUF4366 PF14283.6 OAG44869.1 - 3.3 7.8 7.1 19 5.3 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) Spore_coat_CotO PF14153.6 OAG44869.1 - 9.1 6.2 12.6 23 4.8 12.6 1.8 1 1 0 1 1 1 0 Spore coat protein CotO Mpv17_PMP22 PF04117.12 OAG44872.1 - 5.8e-13 48.9 4.9 1.1e-12 48.0 2.2 2.1 2 0 0 2 2 2 1 Mpv17 / PMP22 family Serinc PF03348.15 OAG44872.1 - 0.1 11.5 2.0 0.14 11.0 2.0 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) PseudoU_synth_1 PF01416.20 OAG44872.1 - 0.11 12.9 0.0 0.94 10.0 0.0 2.1 2 0 0 2 2 2 0 tRNA pseudouridine synthase Cullin PF00888.22 OAG44873.1 - 5.9e-177 590.0 2.8 7.5e-177 589.7 2.8 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 OAG44873.1 - 6.1e-23 80.6 1.9 1.4e-22 79.5 1.9 1.7 1 0 0 1 1 1 1 Cullin protein neddylation domain Antimicrobial_4 PF08024.11 OAG44873.1 - 0.095 12.8 0.2 0.22 11.6 0.2 1.5 1 0 0 1 1 1 0 Ant antimicrobial peptide Rep_fac-A_3 PF08661.11 OAG44874.1 - 3.8e-19 69.0 0.0 4.6e-19 68.7 0.0 1.1 1 0 0 1 1 1 1 Replication factor A protein 3 Ten1 PF12658.7 OAG44874.1 - 0.061 13.3 0.0 0.42 10.6 0.0 2.0 1 1 1 2 2 2 0 Telomere capping, CST complex subunit GATA PF00320.27 OAG44875.1 - 1.9e-06 27.4 0.8 0.014 15.0 0.1 2.5 2 0 0 2 2 2 2 GATA zinc finger Dak1 PF02733.17 OAG44876.1 - 2.9e-102 341.7 0.8 5.2e-102 340.9 0.8 1.3 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 OAG44876.1 - 5.5e-49 166.4 1.6 1.2e-48 165.3 1.6 1.6 1 0 0 1 1 1 1 DAK2 domain RIO1 PF01163.22 OAG44877.1 - 3.7e-45 153.9 0.0 5.6e-45 153.3 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.11 OAG44877.1 - 4.9e-29 100.4 0.0 1.1e-28 99.3 0.0 1.6 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.23 OAG44877.1 - 4.3e-08 33.4 0.4 0.001 19.1 0.1 2.7 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 OAG44877.1 - 2.9e-07 30.0 0.0 0.015 14.7 0.0 2.2 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Kinesin PF00225.23 OAG44878.1 - 1.4e-92 310.2 0.0 1.4e-92 310.2 0.0 3.0 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 OAG44878.1 - 7.6e-22 77.8 0.0 9.2e-18 64.6 0.0 3.6 2 1 1 3 3 3 2 Microtubule binding Filament PF00038.21 OAG44878.1 - 0.0024 17.5 26.0 0.0024 17.5 26.0 7.6 3 2 4 8 8 8 2 Intermediate filament protein CEP63 PF17045.5 OAG44878.1 - 0.0041 17.1 24.5 0.0041 17.1 24.5 6.9 4 1 3 7 7 7 1 Centrosomal protein of 63 kDa S-AdoMet_synt_C PF02773.16 OAG44879.1 - 1.6e-67 225.7 0.2 7.7e-67 223.5 0.0 2.0 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 OAG44879.1 - 1.3e-46 157.8 0.0 2.3e-46 157.0 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 OAG44879.1 - 9.3e-44 148.2 0.5 1.7e-43 147.3 0.1 1.7 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain AdoMet_Synthase PF01941.19 OAG44879.1 - 0.14 10.9 0.2 0.75 8.5 0.1 2.0 1 1 1 2 2 2 0 S-adenosylmethionine synthetase (AdoMet synthetase) ATP_bind_1 PF03029.17 OAG44880.1 - 6.3e-75 252.1 0.0 9.2e-74 248.2 0.0 2.0 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein CLP1_P PF16575.5 OAG44880.1 - 0.00034 20.5 0.0 0.00069 19.5 0.0 1.5 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_14 PF13173.6 OAG44880.1 - 0.00055 20.0 0.0 0.0014 18.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 OAG44880.1 - 0.00062 20.3 0.0 0.0015 19.1 0.0 1.8 2 0 0 2 2 1 1 AAA domain DUF463 PF04317.12 OAG44880.1 - 0.00083 18.4 0.0 0.0013 17.8 0.0 1.2 1 0 0 1 1 1 1 YcjX-like family, DUF463 AAA_16 PF13191.6 OAG44880.1 - 0.0016 18.9 0.0 0.0044 17.4 0.0 1.7 2 1 0 2 2 1 1 AAA ATPase domain cobW PF02492.19 OAG44880.1 - 0.0024 17.5 0.1 0.099 12.2 0.0 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 OAG44880.1 - 0.0026 18.0 0.0 0.0071 16.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 OAG44880.1 - 0.0029 16.7 0.0 0.0049 16.0 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_24 PF13479.6 OAG44880.1 - 0.0037 17.0 0.0 0.0059 16.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OAG44880.1 - 0.0037 17.6 0.1 0.11 12.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 OAG44880.1 - 0.0048 16.6 0.0 0.025 14.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain CbiA PF01656.23 OAG44880.1 - 0.012 15.6 0.0 0.016 15.2 0.0 1.3 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA PF00004.29 OAG44880.1 - 0.014 15.8 0.0 0.031 14.7 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 OAG44880.1 - 0.015 15.7 0.0 0.034 14.5 0.0 1.6 1 0 0 1 1 1 0 RNA helicase NTPase_1 PF03266.15 OAG44880.1 - 0.017 15.1 0.0 0.028 14.3 0.0 1.3 1 0 0 1 1 1 0 NTPase AAA_33 PF13671.6 OAG44880.1 - 0.017 15.3 0.0 0.033 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 OAG44880.1 - 0.018 14.8 1.4 0.023 14.4 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain ArsA_ATPase PF02374.15 OAG44880.1 - 0.018 14.2 0.0 0.035 13.3 0.0 1.4 1 0 0 1 1 1 0 Anion-transporting ATPase TsaE PF02367.17 OAG44880.1 - 0.022 14.8 0.0 0.037 14.0 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 OAG44880.1 - 0.027 14.4 0.0 0.046 13.6 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_7 PF12775.7 OAG44880.1 - 0.03 13.8 0.1 0.075 12.5 0.0 1.7 2 0 0 2 2 1 0 P-loop containing dynein motor region Sigma54_activat PF00158.26 OAG44880.1 - 0.058 13.1 0.0 0.09 12.5 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain ATPase_2 PF01637.18 OAG44880.1 - 0.06 13.3 0.0 0.14 12.1 0.0 1.6 2 0 0 2 2 1 0 ATPase domain predominantly from Archaea APS_kinase PF01583.20 OAG44880.1 - 0.067 13.1 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase SRP54 PF00448.22 OAG44880.1 - 0.068 12.8 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ATPase PF06745.13 OAG44880.1 - 0.11 11.8 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 KaiC IstB_IS21 PF01695.17 OAG44880.1 - 0.12 12.1 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein KAP_NTPase PF07693.14 OAG44880.1 - 0.16 11.2 0.0 0.16 11.2 0.0 1.3 1 1 0 1 1 1 0 KAP family P-loop domain AAA_5 PF07728.14 OAG44880.1 - 0.2 11.6 0.0 0.36 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) GTP_EFTU PF00009.27 OAG44880.1 - 0.23 10.9 0.0 12 5.4 0.0 2.1 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain ResIII PF04851.15 OAG44880.1 - 0.25 11.3 0.0 0.43 10.5 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit ABC_tran PF00005.27 OAG44880.1 - 0.27 11.7 0.5 0.68 10.4 0.0 1.8 2 0 0 2 2 1 0 ABC transporter DUF2075 PF09848.9 OAG44880.1 - 0.28 10.4 0.0 0.38 9.9 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Apq12 PF12716.7 OAG44881.1 - 6.6e-13 48.4 5.6 1.2e-12 47.5 5.6 1.5 1 0 0 1 1 1 1 Nuclear pore assembly and biogenesis MLANA PF14991.6 OAG44881.1 - 0.048 13.9 0.3 0.077 13.3 0.3 1.3 1 0 0 1 1 1 0 Protein melan-A PKcGMP_CC PF16808.5 OAG44882.1 - 0.12 12.3 10.1 11 6.0 0.1 5.3 4 0 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Mt_ATP-synt_D PF05873.12 OAG44882.1 - 8.2 6.3 12.0 0.32 10.9 2.6 3.2 3 0 0 3 3 3 0 ATP synthase D chain, mitochondrial (ATP5H) V-ATPase_H_N PF03224.14 OAG44883.1 - 2.2e-80 270.3 0.3 2.7e-80 270.0 0.3 1.1 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 OAG44883.1 - 6.1e-37 126.3 0.0 3e-36 124.1 0.0 2.2 3 0 0 3 3 3 1 V-ATPase subunit H NAT PF04768.13 OAG44883.1 - 0.055 13.1 0.0 12 5.5 0.0 2.4 2 0 0 2 2 2 0 NAT, N-acetyltransferase, of N-acetylglutamate synthase HEAT PF02985.22 OAG44883.1 - 0.11 12.8 0.1 0.76 10.2 0.0 2.5 2 0 0 2 2 2 0 HEAT repeat TMF_TATA_bd PF12325.8 OAG44884.1 - 2.8e-40 137.1 13.4 2.8e-40 137.1 13.4 6.8 3 1 3 7 7 7 1 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.8 OAG44884.1 - 1.1e-13 50.9 8.8 1.1e-13 50.9 8.8 9.4 6 3 4 10 10 10 1 TATA element modulatory factor 1 DNA binding ATG16 PF08614.11 OAG44884.1 - 0.00023 21.5 7.1 0.00023 21.5 7.1 5.7 3 1 2 5 5 5 1 Autophagy protein 16 (ATG16) Baculo_PEP_C PF04513.12 OAG44884.1 - 0.32 11.0 22.6 1.4 9.0 0.5 4.7 4 1 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus phage_tail_N PF08400.10 OAG44884.1 - 6 6.9 8.6 2.6 8.1 0.3 3.2 3 0 0 3 3 3 0 Prophage tail fibre N-terminal Ank_4 PF13637.6 OAG44885.1 - 5.2e-39 132.1 4.1 2e-10 41.0 0.0 5.5 1 1 5 6 6 6 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 OAG44885.1 - 1.7e-35 121.4 0.1 1.4e-11 44.8 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OAG44885.1 - 6.2e-34 115.6 0.6 7e-11 42.2 0.0 5.1 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 OAG44885.1 - 5.3e-30 102.5 4.8 3e-06 27.4 0.1 6.1 5 1 1 6 6 6 6 Ankyrin repeat Ank_3 PF13606.6 OAG44885.1 - 1e-29 99.2 0.2 6.1e-05 23.1 0.0 6.2 6 0 0 6 6 6 6 Ankyrin repeat Shal-type PF11601.8 OAG44885.1 - 0.059 12.9 1.2 0.38 10.3 0.0 2.3 2 0 0 2 2 2 0 Shal-type voltage-gated potassium channels, N-terminal Fungal_trans PF04082.18 OAG44886.1 - 4.1e-12 45.7 0.1 8.7e-12 44.6 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain K_trans PF02705.16 OAG44887.1 - 7.5e-178 592.4 16.6 9e-178 592.1 16.6 1.0 1 0 0 1 1 1 1 K+ potassium transporter zf-RING_2 PF13639.6 OAG44888.1 - 4.9e-11 42.8 2.4 8e-11 42.1 2.4 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 OAG44888.1 - 1.3e-07 31.4 1.5 2.2e-07 30.6 1.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OAG44888.1 - 1.8e-07 30.7 3.8 2.9e-07 30.1 3.8 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 OAG44888.1 - 1.9e-06 27.6 0.9 3e-06 27.0 0.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAG44888.1 - 0.00013 21.9 3.1 0.00026 21.0 3.1 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 OAG44888.1 - 0.00055 20.2 4.8 0.0022 18.2 4.8 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 OAG44888.1 - 0.00083 19.3 1.0 0.0014 18.5 1.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 OAG44888.1 - 0.0089 15.9 1.2 0.017 15.0 1.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 OAG44888.1 - 0.038 13.6 1.3 0.06 13.0 1.3 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 OAG44888.1 - 0.051 13.5 3.7 0.75 9.7 3.7 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Prok-RING_1 PF14446.6 OAG44888.1 - 0.076 12.9 1.7 0.12 12.3 1.7 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 MLANA PF14991.6 OAG44888.1 - 0.08 13.2 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein melan-A zf-C3HC4_4 PF15227.6 OAG44888.1 - 0.13 12.4 1.5 0.26 11.5 1.5 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 OAG44888.1 - 0.27 11.3 2.9 0.83 9.8 2.9 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DED PF01335.21 OAG44889.1 - 0.077 13.3 0.2 0.99 9.8 0.2 2.3 1 1 0 1 1 1 0 Death effector domain Asp_protease_2 PF13650.6 OAG44890.1 - 0.00096 19.8 0.0 0.0018 18.9 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 OAG44890.1 - 0.034 14.7 0.0 0.055 14.0 0.0 1.3 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease DUF2620 PF10941.8 OAG44890.1 - 0.09 12.9 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF2620 RVP PF00077.20 OAG44890.1 - 0.13 12.6 0.0 0.28 11.5 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease Presenilin PF01080.17 OAG44891.1 - 0.18 10.5 1.1 0.18 10.5 1.1 1.2 1 0 0 1 1 1 0 Presenilin Cadherin_tail PF15974.5 OAG44891.1 - 1.8 8.9 7.9 2.4 8.5 5.4 2.2 3 0 0 3 3 3 0 Cadherin C-terminal cytoplasmic tail, catenin-binding region gag-asp_proteas PF13975.6 OAG44893.1 - 0.17 12.5 0.0 0.77 10.4 0.0 2.1 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease WD40 PF00400.32 OAG44894.1 - 6.2e-46 153.4 16.5 1.1e-09 38.8 0.2 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG44894.1 - 1.5e-06 28.4 0.4 0.74 10.1 0.0 5.0 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OAG44894.1 - 0.0057 15.3 2.0 11 4.5 0.0 4.0 1 1 2 3 3 3 2 Nucleoporin Nup120/160 PQQ_2 PF13360.6 OAG44894.1 - 0.022 14.3 0.4 1.7 8.2 0.0 2.7 1 1 2 4 4 4 0 PQQ-like domain SP_C-Propep PF08999.10 OAG44895.1 - 0.013 15.3 4.2 0.13 12.0 0.9 2.2 2 0 0 2 2 2 0 Surfactant protein C, N terminal propeptide GDPD_2 PF13653.6 OAG44896.1 - 0.0035 17.7 0.2 0.0086 16.5 0.2 1.7 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family ADH_N PF08240.12 OAG44898.1 - 3.1e-28 97.8 0.3 6.1e-28 96.9 0.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_assoc PF13823.6 OAG44898.1 - 4e-10 39.4 0.3 8.8e-10 38.3 0.3 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated ADH_zinc_N PF00107.26 OAG44898.1 - 1.9e-06 27.8 0.2 4.2e-06 26.8 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 OAG44898.1 - 0.001 18.6 0.0 0.0067 15.9 0.0 2.0 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus HI0933_like PF03486.14 OAG44898.1 - 0.0047 15.7 0.1 0.0075 15.0 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein AlaDh_PNT_C PF01262.21 OAG44898.1 - 0.024 14.0 0.1 0.041 13.2 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 OAG44898.1 - 0.054 12.6 0.3 0.083 11.9 0.3 1.2 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.24 OAG44898.1 - 0.061 12.9 0.1 0.12 12.0 0.1 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 OAG44898.1 - 0.13 11.4 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Arm PF00514.23 OAG44899.1 - 1.4e-93 304.4 12.6 6.8e-14 51.4 0.0 8.4 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat IBB PF01749.20 OAG44899.1 - 6e-27 93.9 3.2 1.5e-26 92.7 3.2 1.7 1 0 0 1 1 1 1 Importin beta binding domain Arm_3 PF16186.5 OAG44899.1 - 1.6e-23 82.0 3.2 1.6e-23 82.0 3.2 1.8 2 0 0 2 2 2 1 Atypical Arm repeat HEAT_EZ PF13513.6 OAG44899.1 - 6.1e-19 68.1 4.0 1.7e-08 34.8 0.1 5.9 3 2 3 6 6 6 4 HEAT-like repeat HEAT_2 PF13646.6 OAG44899.1 - 3.7e-18 65.7 3.2 2.7e-09 37.3 0.1 5.3 2 1 4 6 6 5 3 HEAT repeats HEAT PF02985.22 OAG44899.1 - 4.6e-17 60.6 0.1 1.8e-05 24.6 0.0 6.6 7 0 0 7 7 7 3 HEAT repeat Arm_2 PF04826.13 OAG44899.1 - 2.2e-08 33.9 0.0 0.0031 17.0 0.0 3.8 2 1 2 4 4 4 2 Armadillo-like Adaptin_N PF01602.20 OAG44899.1 - 5.9e-06 25.1 0.0 0.00023 19.9 0.0 2.3 1 1 1 2 2 2 1 Adaptin N terminal region V-ATPase_H_C PF11698.8 OAG44899.1 - 0.00016 21.8 0.0 2.1 8.5 0.0 4.5 3 2 1 4 4 4 2 V-ATPase subunit H HEAT_PBS PF03130.16 OAG44899.1 - 0.00052 20.4 0.8 0.8 10.6 0.1 4.4 4 0 0 4 4 4 1 PBS lyase HEAT-like repeat Cnd1 PF12717.7 OAG44899.1 - 0.0024 18.0 0.0 4.4 7.3 0.0 3.1 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 RICTOR_V PF14668.6 OAG44899.1 - 0.12 12.7 5.2 3.1 8.1 0.1 4.5 3 2 2 5 5 5 0 Rapamycin-insensitive companion of mTOR, domain 5 Gcn1_N PF12074.8 OAG44899.1 - 0.17 11.2 0.1 11 5.2 0.0 2.5 2 1 0 2 2 2 0 Generalcontrol nonderepressible 1 (Gcn1) N-terminal Glycos_trans_3N PF02885.17 OAG44899.1 - 0.17 11.7 0.0 43 4.0 0.0 3.5 3 0 0 3 3 3 0 Glycosyl transferase family, helical bundle domain POT1PC PF16686.5 OAG44900.1 - 3.5e-36 124.4 0.2 1.5e-35 122.4 0.1 2.0 2 0 0 2 2 2 1 ssDNA-binding domain of telomere protection protein POT1 PF02765.17 OAG44900.1 - 3.9e-13 49.4 0.0 1.5e-12 47.5 0.0 2.0 2 0 0 2 2 2 1 Telomeric single stranded DNA binding POT1/CDC13 REPA_OB_2 PF16900.5 OAG44900.1 - 0.00038 20.3 0.1 0.0063 16.4 0.0 2.5 2 0 0 2 2 2 1 Replication protein A OB domain Edc3_linker PF16598.5 OAG44900.1 - 0.02 15.5 1.4 0.048 14.3 0.1 2.2 2 0 0 2 2 2 0 Linker region of enhancer of mRNA-decapping protein 3 Uds1 PF15456.6 OAG44900.1 - 5 7.3 8.3 9.5 6.4 8.3 1.4 1 0 0 1 1 1 0 Up-regulated During Septation Fungal_trans PF04082.18 OAG44901.1 - 1.8e-24 86.2 0.0 2.8e-24 85.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 OAG44901.1 - 2.3e-06 27.7 13.7 0.00042 20.6 1.8 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OAG44901.1 - 1e-05 25.7 6.6 1e-05 25.7 6.6 3.0 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 OAG44901.1 - 0.0034 18.1 13.1 0.047 14.5 1.9 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger NOA36 PF06524.12 OAG44901.1 - 0.2 11.0 2.1 5.2 6.3 1.0 2.7 2 0 0 2 2 2 0 NOA36 protein zf_C2H2_ZHX PF18387.1 OAG44901.1 - 6.4 6.5 5.6 15 5.3 0.3 2.5 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain Nha1_C PF08619.10 OAG44902.1 - 5.3e-80 269.9 62.2 4.2e-79 266.9 61.1 2.1 1 1 0 1 1 1 1 Alkali metal cation/H+ antiporter Nha1 C terminus Na_H_Exchanger PF00999.21 OAG44902.1 - 1.7e-73 247.6 24.8 2e-73 247.4 24.8 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.6 OAG44902.1 - 0.009 16.1 0.2 0.009 16.1 0.2 2.6 3 0 0 3 3 3 1 YrhC-like protein FlgD_ig PF13860.6 OAG44902.1 - 0.03 14.2 0.2 4.2 7.3 0.0 2.5 2 0 0 2 2 2 0 FlgD Ig-like domain DUF21 PF01595.20 OAG44902.1 - 1.3 8.7 8.8 0.71 9.6 4.9 2.3 2 0 0 2 2 2 0 Cyclin M transmembrane N-terminal domain Npa1 PF11707.8 OAG44903.1 - 2.7e-66 224.2 0.0 8.7e-66 222.6 0.0 1.9 1 0 0 1 1 1 1 Ribosome 60S biogenesis N-terminal NopRA1 PF16201.5 OAG44903.1 - 1.7e-46 158.4 0.6 1.5e-45 155.3 0.0 3.0 4 0 0 4 4 4 1 Nucleolar pre-ribosomal-associated protein 1 HEAT PF02985.22 OAG44903.1 - 1.9e-05 24.5 0.1 3.4 8.2 0.0 4.0 3 0 0 3 3 3 2 HEAT repeat Creb_binding PF09030.10 OAG44903.1 - 0.0054 17.4 0.2 5.4 7.8 0.0 3.0 2 0 0 2 2 2 2 Creb binding Sec7_N PF12783.7 OAG44903.1 - 0.0066 16.4 0.4 3 7.7 0.0 3.0 3 0 0 3 3 3 2 Guanine nucleotide exchange factor in Golgi transport N-terminal HEAT_2 PF13646.6 OAG44903.1 - 0.071 13.5 0.0 27 5.3 0.0 3.5 2 0 0 2 2 2 0 HEAT repeats RasGEF_N_2 PF14663.6 OAG44903.1 - 0.35 11.3 2.0 20 5.6 0.1 4.5 5 0 0 5 5 5 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain NESP55 PF06390.12 OAG44903.1 - 6.1 6.4 13.5 13 5.3 13.5 1.5 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) Pyr_redox_2 PF07992.14 OAG44904.1 - 5e-40 137.6 0.0 6.8e-40 137.1 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAG44904.1 - 3.6e-12 46.7 0.0 4e-10 40.1 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.32 OAG44904.1 - 5.7e-07 28.6 0.1 3.5e-06 26.2 0.1 2.3 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 OAG44904.1 - 5e-05 22.9 0.3 0.00018 21.1 0.3 2.0 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 OAG44904.1 - 0.00035 21.0 0.1 0.0008 19.8 0.1 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 OAG44904.1 - 0.00039 19.8 0.2 0.0011 18.3 0.2 1.8 1 0 0 1 1 1 1 EF hand Nipped-B_C PF12830.7 OAG44905.1 - 1.2e-33 116.7 1.8 1.2e-33 116.7 1.8 2.9 3 0 0 3 3 3 1 Sister chromatid cohesion C-terminus Cnd1 PF12717.7 OAG44905.1 - 8.4e-06 25.9 3.4 2.8e-05 24.2 0.7 3.3 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Cohesin_HEAT PF12765.7 OAG44905.1 - 7.5e-05 22.9 1.4 0.00036 20.8 0.5 2.8 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion Adaptin_N PF01602.20 OAG44905.1 - 0.00061 18.5 0.5 0.00061 18.5 0.5 2.5 3 0 0 3 3 3 1 Adaptin N terminal region EnY2 PF10163.9 OAG44905.1 - 0.16 12.4 1.2 0.59 10.5 0.0 2.6 3 0 0 3 3 3 0 Transcription factor e(y)2 AT_hook PF02178.19 OAG44905.1 - 0.53 10.3 3.9 2.4 8.3 3.9 2.1 1 0 0 1 1 1 0 AT hook motif HEAT PF02985.22 OAG44905.1 - 3.4 8.2 10.0 0.37 11.2 0.2 4.5 6 0 0 6 6 6 0 HEAT repeat TFIIS_C PF01096.18 OAG44906.1 - 5.1e-13 48.6 2.7 5.1e-13 48.6 2.7 2.5 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) Fer4_21 PF14697.6 OAG44906.1 - 0.014 15.5 2.3 1.6 8.9 2.3 2.4 1 1 0 1 1 1 0 4Fe-4S dicluster domain UCH_1 PF13423.6 OAG44906.1 - 0.034 13.7 0.3 0.04 13.5 0.3 1.1 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Haem_bd PF14376.6 OAG44906.1 - 0.037 14.0 0.2 0.037 14.0 0.2 1.4 1 1 0 1 1 1 0 Haem-binding domain Cytochrom_NNT PF03264.14 OAG44906.1 - 0.081 12.6 1.8 0.25 11.0 1.8 1.8 1 1 0 1 1 1 0 NapC/NirT cytochrome c family, N-terminal region DZR PF12773.7 OAG44906.1 - 0.11 12.5 5.1 6 7.0 5.1 2.5 1 1 0 1 1 1 0 Double zinc ribbon zf-RING_7 PF02591.15 OAG44906.1 - 0.32 11.2 7.8 26 5.1 0.0 3.8 4 0 0 4 4 4 0 C4-type zinc ribbon domain Cytochrome_C7 PF14522.6 OAG44906.1 - 0.41 10.7 6.2 0.076 13.0 2.1 2.0 2 1 0 2 2 2 0 Cytochrome c7 and related cytochrome c Zn-ribbon_8 PF09723.10 OAG44906.1 - 1.4 9.1 8.3 4.1 7.6 0.3 3.1 3 0 0 3 3 3 0 Zinc ribbon domain PHD PF00628.29 OAG44906.1 - 8.3 6.4 11.5 0.48 10.4 3.5 2.7 2 2 1 3 3 3 0 PHD-finger HEAT_2 PF13646.6 OAG44907.1 - 9e-28 96.5 3.4 1.3e-13 51.1 0.0 3.3 2 2 1 3 3 3 2 HEAT repeats HEAT_PBS PF03130.16 OAG44907.1 - 7.5e-21 72.7 0.1 0.006 17.1 0.0 6.5 6 0 0 6 6 6 5 PBS lyase HEAT-like repeat HEAT PF02985.22 OAG44907.1 - 2.4e-08 33.5 4.4 0.12 12.7 0.0 6.3 7 0 0 7 7 7 3 HEAT repeat HEAT_EZ PF13513.6 OAG44907.1 - 1.5e-07 31.8 7.1 0.052 14.1 0.0 5.5 4 1 1 5 5 5 3 HEAT-like repeat Arm PF00514.23 OAG44907.1 - 0.014 15.4 1.0 1.7 8.8 0.0 3.3 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Cohesin_HEAT PF12765.7 OAG44907.1 - 0.033 14.5 0.0 0.35 11.2 0.0 2.5 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion DIM1 PF02966.16 OAG44908.1 - 9.5e-70 232.5 0.3 1.1e-69 232.4 0.3 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 OAG44908.1 - 0.00077 19.4 0.0 0.00096 19.1 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 OAG44908.1 - 0.012 16.0 0.8 0.022 15.1 0.8 1.6 1 1 0 1 1 1 0 Thioredoxin-like EcoEI_R_C PF08463.10 OAG44908.1 - 0.081 13.0 0.1 0.15 12.2 0.1 1.6 1 1 0 1 1 1 0 EcoEI R protein C-terminal PIG-L PF02585.17 OAG44909.1 - 8.7e-25 87.9 0.0 1.6e-24 87.0 0.0 1.4 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase ATP13 PF12921.7 OAG44910.1 - 8.8e-22 77.1 0.0 1.7e-21 76.2 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ATPase expression PPR_3 PF13812.6 OAG44910.1 - 4.1e-06 26.8 0.0 0.00063 19.8 0.0 2.7 2 0 0 2 2 2 2 Pentatricopeptide repeat domain EzrA PF06160.12 OAG44910.1 - 0.068 11.3 0.0 0.1 10.7 0.0 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA GTP_EFTU PF00009.27 OAG44911.1 - 9.6e-19 67.7 0.0 1.7e-18 66.9 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LSM PF01423.22 OAG44911.1 - 3.1e-12 46.0 0.1 7e-12 44.9 0.1 1.6 1 0 0 1 1 1 1 LSM domain GTP_EFTU_D2 PF03144.25 OAG44911.1 - 3.3e-08 33.8 1.6 1.5e-07 31.7 0.5 2.7 3 0 0 3 3 3 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.17 OAG44911.1 - 1.9e-05 24.9 0.0 4.1e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 OAG44911.1 - 0.017 15.2 0.0 0.054 13.6 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase PduV-EutP PF10662.9 OAG44911.1 - 0.041 13.6 0.2 2 8.2 0.0 3.0 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 OAG44911.1 - 0.06 13.2 0.5 5.2 6.9 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase EamA PF00892.20 OAG44912.1 - 2.3e-06 27.8 6.9 2.3e-06 27.8 6.9 2.0 1 1 1 2 2 2 2 EamA-like transporter family TMEM234 PF10639.9 OAG44912.1 - 0.0081 16.2 1.9 0.011 15.8 1.9 1.2 1 0 0 1 1 1 1 Putative transmembrane family 234 DUF4452 PF14618.6 OAG44913.1 - 5.5e-73 244.4 11.5 7.4e-73 244.0 11.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4452) Het-C PF07217.11 OAG44914.1 - 2.3e-264 878.2 0.1 3.6e-263 874.2 0.1 2.0 1 1 0 1 1 1 1 Heterokaryon incompatibility protein Het-C SOG2 PF10428.9 OAG44914.1 - 0.51 9.5 9.1 0.86 8.7 9.1 1.4 1 0 0 1 1 1 0 RAM signalling pathway protein ECH_1 PF00378.20 OAG44915.1 - 3e-42 144.7 0.1 9.4e-42 143.0 0.1 1.7 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAG44915.1 - 8.4e-20 71.5 0.0 2.2e-19 70.2 0.0 1.7 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 OAG44915.1 - 0.008 16.1 0.0 1 9.3 0.0 2.3 2 0 0 2 2 2 2 Peptidase family S49 RSN1_7TM PF02714.15 OAG44916.1 - 7.4e-83 278.0 26.0 1.1e-82 277.5 26.0 1.3 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 OAG44916.1 - 1.1e-42 145.5 5.0 3.8e-42 143.7 0.1 3.1 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 OAG44916.1 - 6.5e-29 101.4 0.2 1.3e-16 61.4 0.0 2.6 2 0 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 OAG44916.1 - 1.1e-13 51.1 0.0 4.1e-13 49.3 0.0 2.0 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter Vps62 PF06101.11 OAG44917.1 - 3.7e-15 55.3 0.9 1.3e-13 50.1 0.1 2.5 3 0 0 3 3 3 2 Vacuolar protein sorting-associated protein 62 Sec2p PF06428.11 OAG44918.1 - 2.4e-11 43.5 9.9 2.4e-11 43.5 9.9 2.2 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p CCDC53 PF10152.9 OAG44918.1 - 0.0075 16.7 3.4 0.0075 16.7 3.4 2.1 2 1 0 2 2 2 1 Subunit CCDC53 of WASH complex Jnk-SapK_ap_N PF09744.9 OAG44918.1 - 0.011 16.0 19.4 0.25 11.5 11.1 2.1 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Med4 PF10018.9 OAG44918.1 - 0.032 13.9 0.6 0.032 13.9 0.6 2.4 2 1 1 3 3 3 0 Vitamin-D-receptor interacting Mediator subunit 4 Exonuc_VII_L PF02601.15 OAG44918.1 - 0.051 13.1 10.7 0.21 11.2 3.1 2.0 2 0 0 2 2 2 0 Exonuclease VII, large subunit BRI3BP PF14965.6 OAG44918.1 - 0.091 12.3 0.3 9.1 5.8 0.0 2.3 2 0 0 2 2 2 0 Negative regulator of p53/TP53 Goodbye PF17109.5 OAG44918.1 - 0.22 12.0 3.3 5.1 7.6 0.1 2.5 2 1 0 2 2 2 0 fungal STAND N-terminal Goodbye domain Cortex-I_coil PF09304.10 OAG44918.1 - 0.23 11.7 16.9 0.054 13.7 10.0 2.4 2 1 0 2 2 2 0 Cortexillin I, coiled coil ECSIT PF06239.11 OAG44918.1 - 0.28 10.3 0.9 0.53 9.4 0.9 1.4 1 0 0 1 1 1 0 Evolutionarily conserved signalling intermediate in Toll pathway YlqD PF11068.8 OAG44918.1 - 0.3 11.5 13.9 1.1 9.6 5.4 2.3 2 0 0 2 2 2 0 YlqD protein HSBP1 PF06825.12 OAG44918.1 - 0.3 11.0 2.5 20 5.1 0.1 3.2 3 0 0 3 3 3 0 Heat shock factor binding protein 1 DUF4407 PF14362.6 OAG44918.1 - 0.36 10.1 13.1 0.24 10.7 1.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) MCU PF04678.13 OAG44918.1 - 1.1 9.3 5.6 10 6.2 4.1 2.1 2 0 0 2 2 2 0 Mitochondrial calcium uniporter CorA PF01544.18 OAG44918.1 - 1.6 7.9 5.6 0.99 8.7 0.2 2.1 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Golgin_A5 PF09787.9 OAG44918.1 - 2.2 7.7 18.0 6.4 6.1 0.6 2.1 2 0 0 2 2 2 0 Golgin subfamily A member 5 Spc7 PF08317.11 OAG44918.1 - 3.4 6.4 17.3 4.3 6.1 0.7 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein YabA PF06156.13 OAG44918.1 - 4.9 7.9 8.5 4.1 8.1 0.1 2.4 2 0 0 2 2 2 0 Initiation control protein YabA DUF2072 PF09845.9 OAG44918.1 - 5.4 7.3 8.7 7.8 6.8 0.5 2.4 2 1 0 2 2 2 0 Zn-ribbon containing protein GCN5L1 PF06320.13 OAG44918.1 - 6.4 7.0 11.1 2.8 8.1 3.8 2.2 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) LMBR1 PF04791.16 OAG44918.1 - 7.5 5.3 9.5 24 3.7 9.6 1.6 1 1 0 1 1 1 0 LMBR1-like membrane protein AAA_13 PF13166.6 OAG44918.1 - 7.7 5.0 11.5 7.4 5.1 5.0 2.0 2 0 0 2 2 2 0 AAA domain ADIP PF11559.8 OAG44918.1 - 8.4 6.5 20.1 4 7.5 2.1 2.3 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding KilA-N PF04383.13 OAG44919.1 - 0.0043 16.9 0.1 0.011 15.6 0.0 1.7 2 0 0 2 2 2 1 KilA-N domain TFIIA PF03153.13 OAG44919.1 - 0.65 9.9 5.9 0.87 9.5 5.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PseudoU_synth_2 PF00849.22 OAG44920.1 - 9.4e-26 90.8 0.0 2.1e-25 89.7 0.0 1.6 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 OAG44920.1 - 2.9e-06 26.9 0.0 5.8e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 S4 domain Auto_anti-p27 PF06677.12 OAG44920.1 - 0.0014 18.7 0.1 0.003 17.7 0.1 1.5 1 0 0 1 1 1 1 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Ribosomal_L32e PF01655.18 OAG44921.1 - 1.9e-47 160.2 0.8 1.9e-47 160.2 0.8 1.7 1 1 1 2 2 2 1 Ribosomal protein L32 GFO_IDH_MocA PF01408.22 OAG44922.1 - 3.8e-20 72.9 0.0 6.7e-20 72.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 OAG44922.1 - 1.8e-05 24.7 0.0 3.4e-05 23.8 0.0 1.4 1 1 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Heme_oxygenase PF01126.20 OAG44923.1 - 5.5e-10 39.4 0.0 1.2e-09 38.3 0.0 1.6 1 1 0 1 1 1 1 Heme oxygenase Adaptin_N PF01602.20 OAG44925.1 - 7.7e-100 334.9 0.0 1e-99 334.5 0.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 OAG44925.1 - 1.5e-15 57.6 0.3 1e-13 51.6 0.0 3.2 2 2 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 OAG44925.1 - 7.1e-09 35.9 0.9 0.0007 19.9 0.0 4.1 2 1 0 2 2 2 2 HEAT repeats HEAT PF02985.22 OAG44925.1 - 5.4e-07 29.3 0.1 0.18 12.1 0.0 5.2 4 0 0 4 4 4 2 HEAT repeat Cohesin_HEAT PF12765.7 OAG44925.1 - 0.0033 17.7 3.2 0.46 10.8 0.0 4.1 4 0 0 4 4 4 1 HEAT repeat associated with sister chromatid cohesion EH_Signature PF15611.6 OAG44925.1 - 0.0082 15.6 0.1 0.016 14.6 0.1 1.4 1 0 0 1 1 1 1 EH_Signature domain Cnd3 PF12719.7 OAG44925.1 - 0.031 13.5 0.1 0.16 11.2 0.0 2.0 2 0 0 2 2 2 0 Nuclear condensing complex subunits, C-term domain Trypan_PARP PF05887.11 OAG44925.1 - 1 9.3 10.4 2.3 8.2 10.4 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) RPN2_C PF18004.1 OAG44925.1 - 3 7.8 6.9 4.9 7.0 6.9 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Nop14 PF04147.12 OAG44925.1 - 9.1 4.4 12.3 17 3.5 12.3 1.3 1 0 0 1 1 1 0 Nop14-like family Nuf2 PF03800.14 OAG44927.1 - 1.3e-39 135.4 0.4 3.6e-39 134.1 0.4 1.8 1 0 0 1 1 1 1 Nuf2 family DHR10 PF18595.1 OAG44927.1 - 9.4e-35 119.2 22.2 9.4e-35 119.2 22.2 4.7 4 1 0 4 4 4 1 Designed helical repeat protein 10 domain SlyX PF04102.12 OAG44927.1 - 0.024 15.3 1.1 0.024 15.3 1.1 5.9 2 2 3 5 5 5 0 SlyX HrpB7 PF09486.10 OAG44927.1 - 0.056 13.8 52.5 0.025 15.0 20.9 3.9 1 1 2 3 3 3 0 Bacterial type III secretion protein (HrpB7) Terminase_3C PF17288.2 OAG44927.1 - 0.7 10.3 6.8 0.17 12.3 2.4 2.2 2 0 0 2 2 2 0 Terminase RNAseH like domain DUF4407 PF14362.6 OAG44927.1 - 5 6.4 37.6 2.4 7.4 10.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) IF-2B PF01008.17 OAG44928.1 - 7.1e-31 107.4 0.0 1.2e-30 106.8 0.0 1.3 1 1 0 1 1 1 1 Initiation factor 2 subunit family GATA PF00320.27 OAG44929.1 - 4.4e-28 96.6 19.3 3.8e-14 52.0 3.9 2.5 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 OAG44929.1 - 3.9e-06 26.3 4.5 0.0032 16.9 0.2 2.5 2 0 0 2 2 2 2 TFIIB zinc-binding Trypsin_2 PF13365.6 OAG44929.1 - 1.4e-05 26.0 0.0 6.3e-05 23.9 0.0 2.2 3 0 0 3 3 3 1 Trypsin-like peptidase domain Zn-ribbon_8 PF09723.10 OAG44929.1 - 0.00047 20.2 3.5 0.22 11.7 0.4 2.6 2 0 0 2 2 2 2 Zinc ribbon domain Auto_anti-p27 PF06677.12 OAG44929.1 - 0.0093 16.1 6.5 0.17 12.1 0.9 2.5 2 0 0 2 2 2 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DZR PF12773.7 OAG44929.1 - 0.041 13.9 7.1 3.4 7.8 0.9 2.8 2 1 0 2 2 2 0 Double zinc ribbon OrfB_Zn_ribbon PF07282.11 OAG44929.1 - 0.059 13.3 6.9 1.1 9.3 1.0 2.5 2 0 0 2 2 2 0 Putative transposase DNA-binding domain eIF-5_eIF-2B PF01873.17 OAG44929.1 - 0.071 13.0 4.2 4.3 7.2 0.2 2.4 2 0 0 2 2 2 0 Domain found in IF2B/IF5 ArfGap PF01412.18 OAG44929.1 - 0.15 12.1 9.9 1.3 9.1 0.2 3.3 4 0 0 4 4 4 0 Putative GTPase activating protein for Arf zf-Sec23_Sec24 PF04810.15 OAG44929.1 - 1.6 8.9 6.5 0.99 9.5 0.4 2.7 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger COPI_assoc PF08507.10 OAG44930.1 - 8.3e-31 106.7 5.2 8.9e-31 106.6 5.2 1.0 1 0 0 1 1 1 1 COPI associated protein OTU PF02338.19 OAG44931.1 - 2.6e-12 47.4 0.0 4e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease Lant_dehydr_C PF14028.6 OAG44931.1 - 0.086 12.4 0.1 2.8 7.4 0.1 2.1 2 0 0 2 2 2 0 Lantibiotic biosynthesis dehydratase C-term DAO PF01266.24 OAG44932.1 - 4.6e-31 108.7 0.8 5.5e-31 108.4 0.8 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAG44932.1 - 3e-05 24.2 0.1 0.00011 22.4 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 OAG44932.1 - 6e-05 22.4 0.0 6e-05 22.4 0.0 2.1 3 0 0 3 3 3 1 Thi4 family Pyr_redox_2 PF07992.14 OAG44932.1 - 0.00038 19.8 1.7 0.004 16.4 0.0 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAG44932.1 - 0.0014 17.8 0.6 0.0021 17.2 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain Thioredoxin PF00085.20 OAG44934.1 - 3.2e-28 97.7 0.2 3.9e-28 97.4 0.2 1.2 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 OAG44934.1 - 8.2e-07 28.7 0.0 8.7e-07 28.6 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 OAG44934.1 - 1.1e-06 29.1 0.1 1.9e-06 28.3 0.1 1.5 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 OAG44934.1 - 6.9e-06 26.3 0.1 0.00012 22.3 0.1 2.2 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.6 OAG44934.1 - 0.0025 17.6 0.1 0.0031 17.3 0.1 1.3 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 OAG44934.1 - 0.0026 17.9 0.1 0.004 17.3 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin-like TraF PF13728.6 OAG44934.1 - 0.0043 16.9 0.1 0.0063 16.4 0.1 1.3 1 1 0 1 1 1 1 F plasmid transfer operon protein Redoxin PF08534.10 OAG44934.1 - 0.007 16.1 0.5 0.26 11.0 0.2 2.1 1 1 1 2 2 2 1 Redoxin DIM1 PF02966.16 OAG44934.1 - 0.028 14.2 0.0 0.033 14.0 0.0 1.2 1 0 0 1 1 1 0 Mitosis protein DIM1 Glutaredoxin PF00462.24 OAG44934.1 - 0.58 10.4 2.7 1.7 8.9 2.7 1.9 1 1 0 1 1 1 0 Glutaredoxin WD40 PF00400.32 OAG44935.1 - 3e-29 100.6 2.5 3.6e-05 24.4 0.1 7.4 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG44935.1 - 1.2e-07 31.9 0.0 0.42 11.0 0.0 4.5 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 OAG44935.1 - 0.00028 19.7 0.0 0.49 9.1 0.0 2.8 2 0 0 2 2 2 2 Nup133 N terminal like eIF2A PF08662.11 OAG44935.1 - 0.01 15.7 0.0 0.064 13.1 0.0 2.2 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A TF_Zn_Ribbon PF08271.12 OAG44935.1 - 0.013 15.0 1.7 0.027 14.0 1.7 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding Lactonase PF10282.9 OAG44935.1 - 0.07 12.4 0.0 9.9 5.3 0.0 3.0 4 0 0 4 4 4 0 Lactonase, 7-bladed beta-propeller DNA_RNApol_7kD PF03604.13 OAG44935.1 - 0.26 11.0 1.9 10 5.9 0.1 2.5 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit zinc_ribbon_4 PF13717.6 OAG44935.1 - 2.2 8.3 5.7 2.7 8.0 0.6 2.5 1 1 1 2 2 2 0 zinc-ribbon domain DCP2 PF05026.13 OAG44936.1 - 5.2e-31 106.8 0.7 9.9e-31 105.9 0.7 1.5 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.28 OAG44936.1 - 1.7e-18 66.9 0.1 3.5e-18 65.9 0.1 1.5 1 0 0 1 1 1 1 NUDIX domain DUF4112 PF13430.6 OAG44937.1 - 4.3e-31 107.3 0.1 5.8e-31 106.9 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) CTU2 PF10288.9 OAG44938.1 - 9.6e-11 41.9 4.0 3.2e-10 40.2 0.0 2.6 2 1 1 3 3 3 1 Cytoplasmic tRNA 2-thiolation protein 2 LIF_OSM PF01291.17 OAG44938.1 - 0.0072 16.5 0.0 0.85 9.7 0.0 2.5 2 0 0 2 2 2 1 LIF / OSM family Lar_restr_allev PF14354.6 OAG44938.1 - 0.015 15.7 0.7 0.04 14.3 0.7 1.7 1 0 0 1 1 1 0 Restriction alleviation protein Lar zf-C2H2_3 PF13878.6 OAG44938.1 - 0.086 12.7 0.4 2.6 8.0 0.2 2.4 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO zf-C3HC4_3 PF13920.6 OAG44938.1 - 0.11 12.4 7.1 2.1 8.3 1.0 3.1 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) DUF1289 PF06945.13 OAG44938.1 - 0.56 10.1 2.9 1.4 8.8 0.0 3.0 4 0 0 4 4 4 0 Protein of unknown function (DUF1289) GFA PF04828.14 OAG44938.1 - 2.2 8.7 5.4 0.6 10.5 0.2 2.4 2 1 0 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme DZR PF12773.7 OAG44938.1 - 4.3 7.4 7.0 2.7 8.1 0.8 2.4 2 0 0 2 2 2 0 Double zinc ribbon adh_short PF00106.25 OAG44940.1 - 1.3e-35 122.6 0.0 4.2e-35 121.0 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG44940.1 - 9.4e-35 120.2 0.0 1.1e-33 116.7 0.0 2.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG44940.1 - 6.8e-10 39.1 0.1 1.2e-09 38.4 0.1 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OAG44940.1 - 1.4e-05 24.3 0.0 0.00011 21.5 0.0 1.9 1 1 1 2 2 2 1 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 OAG44940.1 - 0.01 16.1 0.1 0.019 15.2 0.1 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 OAG44940.1 - 0.017 14.6 0.0 0.025 14.0 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NmrA PF05368.13 OAG44940.1 - 0.022 14.3 0.1 0.55 9.8 0.1 2.1 2 0 0 2 2 2 0 NmrA-like family GCSF PF16647.5 OAG44940.1 - 0.13 12.1 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Granulocyte colony-stimulating factor Shikimate_DH PF01488.20 OAG44940.1 - 0.14 12.2 0.2 0.26 11.4 0.2 1.5 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase HMG_CoA_synt_C PF08540.10 OAG44941.1 - 1.5e-104 349.6 1.5 2e-103 345.9 1.5 2.0 1 1 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 OAG44941.1 - 3.8e-96 319.9 0.2 5.4e-96 319.5 0.2 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal NTF2 PF02136.20 OAG44942.1 - 1.1e-16 61.5 0.1 1.9e-16 60.7 0.1 1.4 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Cg6151-P PF10233.9 OAG44943.1 - 2.1e-42 144.0 13.7 2.5e-42 143.7 13.7 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P COPI_assoc PF08507.10 OAG44943.1 - 0.43 10.6 14.7 0.79 9.8 14.7 1.6 1 1 0 1 1 1 0 COPI associated protein DHHC PF01529.20 OAG44943.1 - 1.3 9.2 6.7 1.8 8.7 6.7 1.3 1 0 0 1 1 1 0 DHHC palmitoyltransferase DUF5592 PF17332.2 OAG44943.1 - 2.8 8.6 7.2 0.6 10.7 3.0 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5592) DUF2207 PF09972.9 OAG44943.1 - 9.6 4.8 12.9 7.3 5.2 11.7 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF3433 PF11915.8 OAG44944.1 - 2.4e-32 111.2 20.8 3.8e-19 68.9 2.4 3.9 3 0 0 3 3 3 3 Protein of unknown function (DUF3433) DIOX_N PF14226.6 OAG44945.1 - 1.8e-28 99.7 0.1 2.6e-28 99.2 0.1 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OAG44945.1 - 2.7e-20 72.7 0.0 4.6e-20 72.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Amidohydro_2 PF04909.14 OAG44946.1 - 3.1e-27 96.1 0.0 4.3e-27 95.6 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase TatD_DNase PF01026.21 OAG44946.1 - 0.033 13.5 0.0 8.1 5.7 0.0 2.2 2 0 0 2 2 2 0 TatD related DNase DnaJ PF00226.31 OAG44948.1 - 3.9e-20 71.7 0.5 1.1e-19 70.3 0.5 1.8 1 0 0 1 1 1 1 DnaJ domain Med9 PF07544.13 OAG44948.1 - 0.055 13.6 2.2 0.13 12.3 2.2 1.7 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Presenilin PF01080.17 OAG44948.1 - 0.55 8.9 2.9 0.66 8.7 2.9 1.1 1 0 0 1 1 1 0 Presenilin Ureide_permease PF07168.11 OAG44948.1 - 9.5 4.9 5.9 1.3 7.7 1.6 1.6 2 0 0 2 2 2 0 Ureide permease GCV_T PF01571.21 OAG44949.1 - 1.2e-06 28.1 0.0 1.9e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain ABM PF03992.16 OAG44950.1 - 0.0028 17.7 0.1 0.004 17.2 0.1 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase CinA_KH PF18146.1 OAG44950.1 - 0.073 13.2 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Damage-inducible protein CinA KH domain ABC2_membrane PF01061.24 OAG44951.1 - 2.1e-82 275.6 57.4 7.7e-43 146.4 22.4 3.5 4 0 0 4 4 4 2 ABC-2 type transporter PDR_CDR PF06422.12 OAG44951.1 - 6e-31 106.2 0.2 2.5e-29 101.0 0.0 3.5 4 0 0 4 4 3 2 CDR ABC transporter ABC_tran PF00005.27 OAG44951.1 - 6.7e-22 78.5 0.0 4e-10 40.4 0.0 3.0 3 0 0 3 3 3 2 ABC transporter ABC_trans_N PF14510.6 OAG44951.1 - 1.1e-13 51.6 1.2 3.6e-13 49.9 0.2 2.5 2 0 0 2 2 2 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 OAG44951.1 - 2.3e-07 30.3 33.6 0.00037 19.7 11.8 3.0 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_18 PF13238.6 OAG44951.1 - 0.0016 19.0 0.3 0.32 11.6 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_16 PF13191.6 OAG44951.1 - 0.0046 17.4 0.1 3.2 8.1 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_33 PF13671.6 OAG44951.1 - 0.0078 16.4 0.0 4.5 7.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.6 OAG44951.1 - 0.032 14.0 0.3 10 5.8 0.1 3.7 3 1 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 OAG44951.1 - 0.05 13.3 0.4 6.1 6.7 0.1 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain dNK PF01712.19 OAG44951.1 - 0.088 12.6 0.0 14 5.5 0.0 2.4 2 0 0 2 2 2 0 Deoxynucleoside kinase SMC_N PF02463.19 OAG44951.1 - 0.16 11.4 0.0 0.29 10.5 0.0 1.7 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_17 PF13207.6 OAG44951.1 - 0.23 11.9 0.2 11 6.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 OAG44951.1 - 0.26 10.8 0.9 5 6.7 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SRP9-21 PF05486.12 OAG44952.1 - 5.9e-27 93.9 3.4 1.5e-26 92.6 3.4 1.6 1 1 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) Ribonuc_red_sm PF00268.21 OAG44953.1 - 8.8e-121 402.6 1.5 1.1e-120 402.3 1.5 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain RE_XcyI PF09571.10 OAG44953.1 - 0.015 14.6 0.1 1 8.5 0.0 2.2 2 0 0 2 2 2 0 XcyI restriction endonuclease Mito_carr PF00153.27 OAG44954.1 - 1.7e-54 181.7 4.3 2.9e-19 68.8 0.3 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein WD40 PF00400.32 OAG44955.1 - 2.5e-13 50.2 3.6 2.9e-05 24.8 0.1 5.3 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG44955.1 - 4e-08 33.5 0.0 0.0033 17.7 0.0 3.5 2 2 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 OAG44955.1 - 0.02 13.2 0.0 0.044 12.1 0.0 1.4 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz Cytochrom_D1 PF02239.16 OAG44955.1 - 0.023 13.2 0.0 4.7 5.6 0.0 2.9 2 2 1 3 3 3 0 Cytochrome D1 heme domain MRG PF05712.13 OAG44955.1 - 0.068 12.5 0.0 0.098 12.0 0.0 1.2 1 0 0 1 1 1 0 MRG WDCP PF15390.6 OAG44955.1 - 0.13 10.6 0.1 0.31 9.4 0.0 1.5 2 0 0 2 2 2 0 WD repeat and coiled-coil-containing protein family DUF1308 PF07000.11 OAG44956.1 - 4.3e-07 30.0 0.2 4.1e-05 23.6 0.0 3.0 2 1 0 2 2 2 1 Protein of unknown function (DUF1308) DUF5614 PF18474.1 OAG44956.1 - 0.0026 17.1 0.0 1.2 8.4 0.0 3.5 3 0 0 3 3 3 1 Family of unknown function (DUF5614) Imm47 PF15573.6 OAG44956.1 - 0.084 12.4 0.1 0.13 11.7 0.1 1.3 1 0 0 1 1 1 0 Immunity protein 47 CLZ PF16526.5 OAG44956.1 - 0.18 12.2 0.8 0.52 10.7 0.8 1.8 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Lung_7-TM_R PF06814.13 OAG44957.1 - 6e-70 235.8 17.1 7.1e-70 235.6 17.1 1.0 1 0 0 1 1 1 1 Lung seven transmembrane receptor OHCU_decarbox PF09349.10 OAG44958.1 - 1.5e-46 158.7 1.9 1.9e-45 155.1 0.2 2.0 2 0 0 2 2 2 2 OHCU decarboxylase Cofilin_ADF PF00241.20 OAG44959.1 - 0.15 11.9 0.0 0.31 10.8 0.0 1.5 1 0 0 1 1 1 0 Cofilin/tropomyosin-type actin-binding protein Thioredoxin PF00085.20 OAG44960.1 - 7.8e-61 202.5 0.0 1.1e-29 102.4 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.12 OAG44960.1 - 1.1e-21 77.6 0.6 5.3e-21 75.3 0.3 2.1 2 0 0 2 2 2 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.6 OAG44960.1 - 1.7e-16 60.6 0.1 3.7e-07 30.5 0.0 3.2 3 1 0 3 3 3 2 Thioredoxin-like domain OST3_OST6 PF04756.13 OAG44960.1 - 6e-13 48.8 0.0 3.4e-06 26.6 0.0 2.1 1 1 1 2 2 2 2 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 OAG44960.1 - 2.8e-09 37.0 0.0 0.00055 19.9 0.0 2.3 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_8 PF13905.6 OAG44960.1 - 6.9e-09 35.9 0.0 0.0042 17.4 0.0 3.5 3 1 1 4 4 4 2 Thioredoxin-like Thioredoxin_7 PF13899.6 OAG44960.1 - 4.6e-08 33.1 0.2 0.0025 17.9 0.0 2.7 3 0 0 3 3 3 2 Thioredoxin-like Redoxin PF08534.10 OAG44960.1 - 1.6e-06 27.9 0.2 0.0063 16.2 0.0 2.3 2 0 0 2 2 2 2 Redoxin Thioredoxin_9 PF14595.6 OAG44960.1 - 0.00052 19.8 0.0 0.48 10.2 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin HyaE PF07449.11 OAG44960.1 - 0.00057 19.8 0.0 0.076 13.0 0.0 2.5 2 0 0 2 2 2 1 Hydrogenase-1 expression protein HyaE Thioredoxin_3 PF13192.6 OAG44960.1 - 0.0014 18.7 0.0 0.46 10.6 0.0 2.8 2 0 0 2 2 2 1 Thioredoxin domain TraF PF13728.6 OAG44960.1 - 0.0017 18.3 0.0 0.067 13.0 0.0 2.3 2 0 0 2 2 2 1 F plasmid transfer operon protein Thioredoxin_4 PF13462.6 OAG44960.1 - 0.0024 18.1 0.3 4.2 7.5 0.0 3.3 3 1 1 4 4 4 2 Thioredoxin Glutaredoxin PF00462.24 OAG44960.1 - 0.0076 16.4 0.1 6.9 7.0 0.0 3.1 2 1 0 2 2 2 1 Glutaredoxin DDE_Tnp_1_2 PF13586.6 OAG44960.1 - 0.2 12.1 0.0 6.8 7.1 0.0 2.4 2 0 0 2 2 2 0 Transposase DDE domain HSBP1 PF06825.12 OAG44961.1 - 2.4e-11 43.3 1.2 3.3e-11 42.9 1.2 1.2 1 0 0 1 1 1 1 Heat shock factor binding protein 1 PhoU_div PF01865.16 OAG44961.1 - 0.09 12.1 0.1 0.11 11.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF47 APH PF01636.23 OAG44962.1 - 5.4e-15 56.0 0.0 1.4e-14 54.6 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 OAG44962.1 - 0.041 12.8 0.0 0.61 8.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) DPM3 PF08285.11 OAG44964.1 - 0.01 16.0 1.9 0.015 15.5 0.2 2.2 2 0 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) FAD_binding_3 PF01494.19 OAG44966.1 - 7.6e-96 321.4 0.0 1e-95 321.0 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAG44966.1 - 1.7e-08 34.5 1.5 0.0016 18.1 0.8 2.6 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG44966.1 - 2e-06 27.2 2.1 0.02 14.1 0.1 2.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAG44966.1 - 5.8e-06 26.8 0.2 0.03 14.9 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAG44966.1 - 3.1e-05 23.3 0.9 0.022 13.9 0.2 2.3 1 1 1 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 OAG44966.1 - 0.00034 20.8 0.3 0.00086 19.5 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 OAG44966.1 - 0.024 14.0 0.0 0.64 9.3 0.0 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.17 OAG44966.1 - 0.072 12.3 0.1 0.15 11.3 0.1 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 OAG44966.1 - 0.19 10.9 0.7 0.53 9.5 0.2 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAG44966.1 - 0.22 10.2 0.5 3.2 6.3 0.1 2.1 2 0 0 2 2 2 0 HI0933-like protein Ebp2 PF05890.12 OAG44967.1 - 6.7e-87 291.4 11.7 6.7e-87 291.4 11.7 2.0 2 0 0 2 2 2 1 Eukaryotic rRNA processing protein EBP2 DNMT1-RFD PF12047.8 OAG44968.1 - 0.0065 16.5 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 Cytosine specific DNA methyltransferase replication foci domain BSP_II PF05432.11 OAG44968.1 - 0.028 14.1 12.9 0.053 13.2 12.9 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) CDC45 PF02724.14 OAG44968.1 - 0.26 9.6 4.8 0.34 9.2 4.8 1.2 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 OAG44968.1 - 0.26 9.4 7.2 0.45 8.6 7.2 1.3 1 0 0 1 1 1 0 DNA polymerase phi CobT PF06213.12 OAG44968.1 - 0.6 9.4 12.9 0.3 10.4 10.0 1.8 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT RR_TM4-6 PF06459.12 OAG44968.1 - 7.9 6.2 7.9 11 5.8 2.7 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Roughex PF06020.11 OAG44968.1 - 9.1 5.3 7.6 41 3.1 6.2 2.1 2 0 0 2 2 2 0 Drosophila roughex protein TruB_N PF01509.18 OAG44969.1 - 4e-44 150.6 0.1 7.6e-42 143.2 0.0 2.2 1 1 1 2 2 2 2 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 OAG44969.1 - 0.034 14.3 0.0 0.066 13.4 0.0 1.5 1 0 0 1 1 1 0 tRNA pseudouridylate synthase B C-terminal domain DUF1857 PF08982.11 OAG44969.1 - 0.22 11.3 2.6 0.3 10.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1857) Pkinase PF00069.25 OAG44970.1 - 3.1e-25 89.0 0.0 4.2e-25 88.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG44970.1 - 7.5e-12 45.1 0.1 1.4e-10 40.9 0.0 2.5 2 1 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 OAG44970.1 - 0.012 15.6 0.4 0.025 14.5 0.4 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 OAG44970.1 - 0.053 13.1 0.4 0.11 12.1 0.4 1.5 1 1 0 1 1 1 0 RIO1 family DOT1 PF08123.13 OAG44971.1 - 5.5e-72 241.6 0.0 1e-71 240.7 0.0 1.4 1 0 0 1 1 1 1 Histone methylation protein DOT1 ATG16 PF08614.11 OAG44972.1 - 2.1e-50 171.8 14.5 2.4e-50 171.6 14.5 1.0 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) UPF0242 PF06785.11 OAG44972.1 - 0.00064 19.9 14.8 0.0057 16.8 6.8 2.7 1 1 2 3 3 3 1 Uncharacterised protein family (UPF0242) N-terminus CCDC144C PF14915.6 OAG44972.1 - 0.0014 17.8 11.4 0.0014 17.8 11.4 1.4 2 0 0 2 2 2 1 CCDC144C protein coiled-coil region GvpG PF05120.12 OAG44972.1 - 0.0031 17.5 7.2 1 9.4 0.1 2.6 1 1 0 2 2 2 2 Gas vesicle protein G Lebercilin PF15619.6 OAG44972.1 - 0.0033 17.1 13.5 0.0033 17.1 13.5 1.9 2 0 0 2 2 2 1 Ciliary protein causing Leber congenital amaurosis disease DUF2968 PF11180.8 OAG44972.1 - 0.0038 16.9 2.3 0.0038 16.9 2.3 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2968) Metal_resist PF13801.6 OAG44972.1 - 0.012 15.8 4.0 0.012 15.8 4.0 2.2 1 1 1 2 2 2 0 Heavy-metal resistance FAM76 PF16046.5 OAG44972.1 - 0.015 14.7 4.1 0.02 14.3 4.1 1.3 1 0 0 1 1 1 0 FAM76 protein Atg14 PF10186.9 OAG44972.1 - 0.021 13.9 5.6 0.029 13.5 5.6 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4201 PF13870.6 OAG44972.1 - 0.068 12.9 17.2 0.02 14.7 13.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) KIAA1430 PF13879.6 OAG44972.1 - 0.091 13.5 0.9 0.091 13.5 0.9 2.5 2 1 1 3 3 2 0 KIAA1430 homologue TMF_DNA_bd PF12329.8 OAG44972.1 - 0.35 10.9 19.2 0.13 12.3 2.1 3.3 2 1 2 4 4 4 0 TATA element modulatory factor 1 DNA binding CENP-H PF05837.12 OAG44972.1 - 0.43 11.0 21.5 0.94 9.9 6.0 3.1 2 1 1 3 3 3 0 Centromere protein H (CENP-H) DUF4763 PF15960.5 OAG44972.1 - 0.49 9.7 10.4 0.11 11.8 2.9 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4763) LMBR1 PF04791.16 OAG44972.1 - 0.55 9.1 2.2 0.57 9.0 2.2 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein ZapB PF06005.12 OAG44972.1 - 0.61 10.6 17.8 0.53 10.8 1.5 3.7 2 1 1 3 3 3 0 Cell division protein ZapB TPR_MLP1_2 PF07926.12 OAG44972.1 - 0.64 10.1 22.1 0.061 13.4 7.0 3.3 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein DUF4407 PF14362.6 OAG44972.1 - 0.73 9.1 14.0 1.7 8.0 14.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) HOOK PF05622.12 OAG44972.1 - 1.1 7.3 16.7 0.5 8.4 14.3 1.6 2 0 0 2 2 2 0 HOOK protein HMMR_N PF15905.5 OAG44972.1 - 1.1 8.6 16.4 0.22 10.9 13.0 1.4 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Fez1 PF06818.15 OAG44972.1 - 1.4 9.3 14.6 2.1 8.8 12.8 2.0 1 1 1 2 2 2 0 Fez1 Spc7 PF08317.11 OAG44972.1 - 1.6 7.6 19.2 0.036 12.9 2.9 2.6 2 1 1 3 3 3 0 Spc7 kinetochore protein Cnn_1N PF07989.11 OAG44972.1 - 1.8 8.7 19.6 2.6 8.3 5.2 3.6 2 1 2 4 4 4 0 Centrosomin N-terminal motif 1 Golgin_A5 PF09787.9 OAG44972.1 - 2 7.8 14.4 0.31 10.5 10.8 1.4 2 0 0 2 2 2 0 Golgin subfamily A member 5 DUF4164 PF13747.6 OAG44972.1 - 3.1 8.1 23.2 0.24 11.7 8.0 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4164) DUF1664 PF07889.12 OAG44972.1 - 3.5 7.7 6.7 1.8 8.6 3.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF3450 PF11932.8 OAG44972.1 - 4.2 6.6 18.8 1.2 8.4 10.5 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) APG6_N PF17675.1 OAG44972.1 - 5.4 7.6 25.3 36 4.9 9.0 3.0 1 1 1 2 2 2 0 Apg6 coiled-coil region HAUS-augmin3 PF14932.6 OAG44972.1 - 6.6 6.2 12.8 2.4 7.6 9.0 2.1 2 1 0 2 2 2 0 HAUS augmin-like complex subunit 3 Ras PF00071.22 OAG44973.1 - 2.1e-57 193.3 0.1 2.4e-57 193.1 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAG44973.1 - 4.5e-33 114.0 0.0 6.9e-33 113.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAG44973.1 - 4.5e-13 49.0 0.0 5.3e-13 48.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OAG44973.1 - 2.1e-08 34.2 0.0 3.1e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OAG44973.1 - 6.4e-07 29.0 0.0 8e-07 28.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 OAG44973.1 - 3.6e-06 26.6 0.0 9.2e-05 22.1 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OAG44973.1 - 1.5e-05 24.9 0.1 0.0021 18.0 0.1 2.3 1 1 0 2 2 2 1 RsgA GTPase cobW PF02492.19 OAG44973.1 - 0.001 18.7 0.0 0.0071 16.0 0.0 2.0 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.17 OAG44973.1 - 0.0021 17.9 0.1 0.059 13.1 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein PduV-EutP PF10662.9 OAG44973.1 - 0.0023 17.7 0.1 0.1 12.4 0.1 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 OAG44973.1 - 0.0043 16.5 0.0 0.0053 16.2 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 OAG44973.1 - 0.008 16.6 0.0 0.011 16.1 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain Septin PF00735.18 OAG44973.1 - 0.013 14.8 0.1 0.025 13.8 0.1 1.5 1 0 0 1 1 1 0 Septin AAA_22 PF13401.6 OAG44973.1 - 0.017 15.4 0.0 0.028 14.7 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 OAG44973.1 - 0.02 14.4 0.1 0.034 13.7 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 OAG44973.1 - 0.021 14.6 0.0 0.035 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 OAG44973.1 - 0.065 13.1 0.1 0.11 12.4 0.1 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea NTPase_1 PF03266.15 OAG44973.1 - 0.065 13.1 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 NTPase AAA_5 PF07728.14 OAG44973.1 - 0.1 12.6 0.0 0.26 11.3 0.0 1.7 1 1 1 2 2 2 0 AAA domain (dynein-related subfamily) TniB PF05621.11 OAG44973.1 - 0.11 11.9 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein NACHT PF05729.12 OAG44973.1 - 0.12 12.3 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 NACHT domain NB-ARC PF00931.22 OAG44973.1 - 0.13 11.4 0.0 0.22 10.7 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain DAP3 PF10236.9 OAG44973.1 - 0.35 10.0 0.9 0.37 9.9 0.2 1.4 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 WD40 PF00400.32 OAG44974.1 - 3.4e-36 122.6 15.2 4.3e-05 24.2 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG44974.1 - 1.1e-14 54.5 0.0 0.00035 20.8 0.1 5.0 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OAG44974.1 - 1.9e-05 24.6 0.0 0.11 12.3 0.0 3.0 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 OAG44974.1 - 0.0028 17.0 0.0 0.083 12.2 0.0 2.8 1 1 2 3 3 3 1 WD40-like domain Ge1_WD40 PF16529.5 OAG44974.1 - 0.054 12.4 0.2 19 4.1 0.0 3.3 3 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Epimerase PF01370.21 OAG44975.1 - 5e-12 45.8 0.0 9.2e-12 44.9 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OAG44975.1 - 4.1e-07 29.3 0.0 6.3e-07 28.7 0.0 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 OAG44975.1 - 1.2e-06 28.2 0.0 1.6e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 OAG44975.1 - 5.9e-05 22.4 0.0 0.00086 18.6 0.0 2.3 1 1 1 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.6 OAG44975.1 - 0.00044 20.2 0.0 0.00066 19.6 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 OAG44975.1 - 0.0012 18.1 0.0 0.0016 17.6 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 OAG44975.1 - 0.0074 15.4 0.0 0.014 14.5 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain FAA_hydrolase PF01557.18 OAG44976.1 - 3.4e-47 160.9 0.0 5.6e-47 160.2 0.0 1.3 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 OAG44976.1 - 1.1e-22 80.3 0.0 1.5e-22 79.8 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal TRI12 PF06609.13 OAG44977.1 - 1.3e-27 96.6 17.2 1.7e-27 96.2 17.2 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG44977.1 - 1.1e-21 77.1 43.1 5.5e-20 71.6 40.1 2.9 2 1 0 2 2 2 2 Major Facilitator Superfamily AMP-binding PF00501.28 OAG44978.1 - 1.5e-45 155.6 0.0 2.3e-45 155.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 OAG44978.1 - 1.2e-05 25.2 1.0 3e-05 23.9 0.1 2.1 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus FAA_hydrolase PF01557.18 OAG44979.1 - 3.2e-58 197.0 0.0 3.8e-58 196.7 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Cupin_2 PF07883.11 OAG44980.1 - 2.3e-08 33.6 0.0 3.6e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 OAG44980.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Aldo_ket_red PF00248.21 OAG44981.1 - 1.4e-64 218.1 0.0 2.5e-64 217.3 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family FliD_C PF07195.12 OAG44981.1 - 0.078 12.4 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus NT5C PF06941.12 OAG44981.1 - 0.11 12.4 0.0 0.26 11.1 0.0 1.7 2 0 0 2 2 2 0 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) FAA_hydrolase PF01557.18 OAG44982.1 - 5.5e-63 212.5 0.0 9e-63 211.9 0.0 1.3 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAD_binding_3 PF01494.19 OAG44982.1 - 5.1e-52 177.3 0.0 7.4e-52 176.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 OAG44982.1 - 1.1e-06 27.7 0.1 7.5e-05 21.6 0.3 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.14 OAG44982.1 - 2.4e-06 27.0 0.3 0.00043 19.6 0.3 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 OAG44982.1 - 3.3e-06 26.6 0.0 0.004 16.5 0.0 2.9 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 OAG44982.1 - 3.2e-05 23.2 0.5 0.00034 19.8 0.7 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 OAG44982.1 - 4.9e-05 23.5 0.3 0.00014 22.0 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 OAG44982.1 - 8e-05 21.9 1.2 0.00014 21.1 1.2 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 OAG44982.1 - 0.00013 21.3 0.0 0.0015 17.8 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAG44982.1 - 0.00018 22.0 0.2 0.0024 18.4 0.2 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAG44982.1 - 0.00022 20.9 0.6 0.00043 20.0 0.3 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 OAG44982.1 - 0.00098 19.1 0.2 0.36 10.8 0.1 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.17 OAG44982.1 - 0.0014 17.9 0.1 0.0024 17.1 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Trp_halogenase PF04820.14 OAG44982.1 - 0.0035 16.3 0.4 0.11 11.3 0.2 2.2 2 0 0 2 2 2 1 Tryptophan halogenase SE PF08491.10 OAG44982.1 - 0.019 14.0 0.0 0.087 11.9 0.0 1.9 2 0 0 2 2 2 0 Squalene epoxidase GIDA PF01134.22 OAG44982.1 - 0.037 13.1 0.9 0.054 12.6 0.9 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A ApbA PF02558.16 OAG44982.1 - 0.12 12.0 0.8 1.2 8.8 0.8 2.3 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Glu_dehyd_C PF16912.5 OAG44982.1 - 0.19 11.2 0.0 0.49 9.9 0.0 1.6 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus 3HCDH_N PF02737.18 OAG44982.1 - 0.19 11.6 0.2 0.31 10.9 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.7 OAG44982.1 - 0.22 10.8 1.9 0.52 9.6 0.7 2.0 3 0 0 3 3 3 0 FAD dependent oxidoreductase Fungal_trans PF04082.18 OAG44983.1 - 1.5e-16 60.2 0.2 2.6e-16 59.4 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.18 OAG44984.1 - 7e-11 41.6 1.2 2.9e-10 39.6 1.2 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain SnoaL_4 PF13577.6 OAG44985.1 - 0.034 14.3 0.0 0.039 14.1 0.0 1.2 1 0 0 1 1 1 0 SnoaL-like domain MFS_1 PF07690.16 OAG44986.1 - 4.4e-24 85.1 38.5 4.4e-24 85.1 38.5 1.7 2 1 1 3 3 3 1 Major Facilitator Superfamily Glyoxalase PF00903.25 OAG44987.1 - 5.5e-08 33.1 0.0 7.9e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Myb_Cef PF11831.8 OAG44987.1 - 0.12 12.0 0.1 0.17 11.4 0.1 1.2 1 0 0 1 1 1 0 pre-mRNA splicing factor component zf-MYND PF01753.18 OAG44988.1 - 0.083 13.0 12.2 0.18 11.9 12.2 1.6 1 0 0 1 1 1 0 MYND finger DIOX_N PF14226.6 OAG44989.1 - 1.6e-18 67.5 0.0 2.5e-18 66.9 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OAG44989.1 - 2.5e-14 53.6 0.0 4.7e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MKT1_C PF12246.8 OAG44990.1 - 1.1e-57 195.0 0.0 1.6e-57 194.5 0.0 1.2 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.8 OAG44990.1 - 6.6e-27 93.7 0.0 1.7e-26 92.4 0.0 1.8 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_I PF00867.18 OAG44990.1 - 0.00019 21.7 0.1 0.00047 20.5 0.1 1.7 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 OAG44990.1 - 0.00022 21.7 0.0 0.00059 20.3 0.0 1.8 1 0 0 1 1 1 1 XPG N-terminal domain EamA PF00892.20 OAG44991.1 - 2.3e-09 37.5 36.5 4e-06 27.0 7.4 3.1 3 0 0 3 3 3 3 EamA-like transporter family DUF3955 PF13127.6 OAG44991.1 - 6.4e-09 35.5 3.8 6.4e-09 35.5 3.8 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF3955) SLC35F PF06027.12 OAG44991.1 - 0.0013 18.3 3.6 0.0078 15.8 0.6 2.7 2 1 0 2 2 2 1 Solute carrier family 35 RCC1_2 PF13540.6 OAG44992.1 - 1.1e-13 50.6 10.7 0.00046 19.9 0.0 5.0 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat F-box PF00646.33 OAG44992.1 - 4.7e-05 23.2 0.0 0.00011 22.0 0.0 1.6 1 0 0 1 1 1 1 F-box domain RCC1 PF00415.18 OAG44992.1 - 0.011 16.4 3.2 4.5 8.0 1.7 4.5 5 1 0 5 5 5 0 Regulator of chromosome condensation (RCC1) repeat F-box-like PF12937.7 OAG44992.1 - 0.03 14.2 0.2 0.064 13.2 0.2 1.6 1 0 0 1 1 1 0 F-box-like Ran_BP1 PF00638.18 OAG44993.1 - 8.7e-50 168.1 0.9 1.6e-49 167.2 0.9 1.4 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.23 OAG44993.1 - 0.00034 20.5 0.1 0.0023 17.8 0.1 2.0 1 1 0 1 1 1 1 WH1 domain VID27_PH PF17747.1 OAG44993.1 - 0.0078 16.5 0.0 0.012 15.9 0.0 1.3 1 0 0 1 1 1 1 VID27 PH-like domain CDC27 PF09507.10 OAG44993.1 - 0.056 12.8 19.9 0.074 12.4 19.9 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 YEATS PF03366.16 OAG44994.1 - 5.1e-16 58.4 0.1 8.9e-16 57.6 0.1 1.4 1 0 0 1 1 1 1 YEATS family BET PF17035.5 OAG44994.1 - 1.4e-05 25.2 0.2 3.2e-05 24.0 0.2 1.6 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation Phosducin PF02114.16 OAG44995.1 - 1.8e-10 40.2 0.3 3.8e-10 39.2 0.0 1.6 2 0 0 2 2 2 1 Phosducin PTCB-BRCT PF12738.7 OAG44996.1 - 1.8e-47 159.1 0.6 1.8e-20 72.6 0.1 4.4 4 0 0 4 4 4 4 twin BRCT domain BRCT PF00533.26 OAG44996.1 - 4.4e-32 110.3 0.0 1.7e-10 41.1 0.0 4.4 4 0 0 4 4 4 4 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 OAG44996.1 - 2e-15 57.0 0.1 0.00016 22.0 0.0 4.4 4 0 0 4 4 4 4 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 OAG44996.1 - 1.2e-06 28.7 1.4 1.7 9.0 0.0 4.3 4 0 0 4 4 4 2 DNA ligase 3 BRCT domain BRCT_3 PF18428.1 OAG44996.1 - 0.0041 17.1 0.0 1.8 8.7 0.0 3.5 4 0 0 4 4 4 1 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 OAG44996.1 - 0.016 15.1 0.0 1 9.3 0.0 3.4 4 0 0 4 4 4 0 Regulator of Ty1 transposition protein 107 BRCT domain Arrestin_C PF02752.22 OAG44997.1 - 5.7e-21 75.4 0.0 1.9e-20 73.7 0.0 1.9 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 OAG44997.1 - 3.2e-08 33.8 0.0 6.3e-05 23.1 0.0 2.5 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Mhr1 PF12829.7 OAG44998.1 - 6.5e-27 93.4 0.0 1.5e-26 92.2 0.0 1.7 1 0 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination vATP-synt_E PF01991.18 OAG44998.1 - 0.016 14.6 4.8 0.025 14.0 3.4 1.9 2 0 0 2 2 2 0 ATP synthase (E/31 kDa) subunit Nbl1_Borealin_N PF10444.9 OAG44998.1 - 0.17 11.6 2.2 0.49 10.1 2.2 1.8 1 0 0 1 1 1 0 Nbl1 / Borealin N terminal PH PF00169.29 OAG44999.1 - 2.4e-26 92.3 0.9 4e-14 53.0 0.1 2.3 2 0 0 2 2 2 2 PH domain PH_11 PF15413.6 OAG44999.1 - 3.5e-08 33.8 3.1 0.0032 17.9 0.8 3.6 2 2 0 2 2 2 2 Pleckstrin homology domain PH_9 PF15410.6 OAG44999.1 - 4.8e-08 33.4 0.4 0.017 15.5 0.1 3.5 2 1 0 2 2 2 2 Pleckstrin homology domain PH_3 PF14593.6 OAG44999.1 - 0.00024 21.2 0.0 0.91 9.7 0.0 2.4 2 0 0 2 2 2 2 PH domain PH_6 PF15406.6 OAG44999.1 - 0.01 16.1 0.0 1.5 9.2 0.0 2.5 2 0 0 2 2 2 1 Pleckstrin homology domain Mcp5_PH PF12814.7 OAG44999.1 - 0.016 15.4 0.1 0.034 14.2 0.1 1.6 1 0 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology PH_13 PF16652.5 OAG44999.1 - 0.046 13.5 0.3 1.8 8.4 0.1 2.3 2 0 0 2 2 2 0 Pleckstrin homology domain Glyco_transf_15 PF01793.16 OAG45000.1 - 5e-96 321.8 12.1 2e-95 319.8 12.1 1.7 1 1 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase DAPDH_C PF16654.5 OAG45000.1 - 0.17 11.7 0.3 0.36 10.7 0.0 1.6 2 0 0 2 2 2 0 Diaminopimelic acid dehydrogenase C-terminal domain Chs7 PF12271.8 OAG45002.1 - 1.3e-121 405.4 16.7 1.5e-121 405.2 16.7 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone DUF4282 PF14110.6 OAG45002.1 - 0.024 15.4 3.6 0.024 15.4 3.6 4.0 3 1 0 3 3 3 0 Domain of unknown function (DUF4282) DUF3382 PF11862.8 OAG45002.1 - 0.81 10.0 8.3 0.13 12.5 2.4 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3382) Lactamase_B_2 PF12706.7 OAG45003.1 - 3.8e-17 62.5 2.7 2.2e-16 60.0 2.7 2.0 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 OAG45003.1 - 4.8e-13 49.3 2.2 1.5e-12 47.7 2.2 1.8 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 OAG45003.1 - 0.0027 17.8 9.3 0.013 15.5 6.6 2.7 1 1 1 2 2 2 1 Metallo-beta-lactamase superfamily DUF3898 PF13037.6 OAG45003.1 - 0.18 11.9 0.0 0.34 11.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3898) Cyclin PF08613.11 OAG45004.1 - 1.3e-13 51.6 0.0 1.9e-13 51.1 0.0 1.2 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 OAG45004.1 - 0.012 15.4 0.0 0.019 14.7 0.0 1.3 1 0 0 1 1 1 0 Cyclin, N-terminal domain Abhydrolase_6 PF12697.7 OAG45005.1 - 2.1e-05 25.3 5.5 2.3e-05 25.1 4.1 1.9 2 1 0 2 2 2 1 Alpha/beta hydrolase family PGAP1 PF07819.13 OAG45005.1 - 0.00045 20.0 0.0 0.00078 19.2 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.14 OAG45005.1 - 0.006 16.1 0.0 0.013 15.1 0.0 1.5 2 0 0 2 2 2 1 Putative serine esterase (DUF676) Thioesterase PF00975.20 OAG45005.1 - 0.016 15.3 0.0 0.094 12.8 0.0 2.2 3 0 0 3 3 3 0 Thioesterase domain Hydrolase_4 PF12146.8 OAG45005.1 - 0.019 14.2 0.0 0.037 13.3 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 OAG45005.1 - 0.066 13.1 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold LCAT PF02450.15 OAG45005.1 - 0.18 10.9 0.0 0.33 10.1 0.0 1.4 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF900 PF05990.12 OAG45005.1 - 0.18 11.3 0.0 0.96 8.9 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) LIDHydrolase PF10230.9 OAG45005.1 - 0.25 10.9 0.0 0.33 10.4 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase PEPcase_2 PF14010.6 OAG45006.1 - 0.0084 14.7 0.0 0.0088 14.6 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxylase CsbD PF05532.12 OAG45006.1 - 0.17 11.9 0.1 0.17 11.9 0.1 2.6 3 0 0 3 3 3 0 CsbD-like DUF2613 PF11021.8 OAG45006.1 - 7.2 6.8 6.0 0.69 10.1 0.3 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2613) 4HBT_3 PF13622.6 OAG45007.1 - 2.3e-32 113.2 0.4 3e-32 112.8 0.4 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 OAG45007.1 - 3.1e-07 30.3 0.1 0.013 15.3 0.1 2.5 2 0 0 2 2 2 2 Acyl-CoA thioesterase Tax PF02959.16 OAG45007.1 - 0.086 12.3 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 HTLV Tax SKG6 PF08693.10 OAG45008.1 - 1.1e-06 27.9 0.3 2.1e-06 27.0 0.3 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF111 PF01969.17 OAG45008.1 - 0.0041 16.3 0.1 0.005 16.0 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function DUF111 Rax2 PF12768.7 OAG45008.1 - 0.021 14.3 0.0 0.034 13.6 0.0 1.3 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Adeno_E3_CR2 PF02439.15 OAG45008.1 - 0.022 14.5 0.8 0.043 13.6 0.8 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Acetyltransf_7 PF13508.7 OAG45009.1 - 4.4e-09 36.6 0.0 1.9e-08 34.6 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OAG45009.1 - 7.8e-09 35.5 0.0 1.8e-08 34.3 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAG45009.1 - 1.1e-07 32.1 0.0 2.6e-07 30.9 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 OAG45009.1 - 7.4e-05 22.6 0.0 0.00011 22.1 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 OAG45009.1 - 0.00025 21.1 0.1 0.39 10.8 0.0 2.5 3 0 0 3 3 3 2 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 OAG45009.1 - 0.014 15.5 0.0 0.022 14.9 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase ADH_N PF08240.12 OAG45010.1 - 1.2e-26 92.7 2.6 2e-26 92.0 2.6 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG45010.1 - 3.4e-15 56.2 0.0 6.4e-15 55.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAG45010.1 - 0.00012 23.2 0.0 0.00022 22.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ThiF PF00899.21 OAG45010.1 - 0.012 15.0 0.9 0.02 14.3 0.9 1.3 1 0 0 1 1 1 0 ThiF family ELFV_dehydrog PF00208.21 OAG45010.1 - 0.014 15.2 0.1 0.025 14.3 0.1 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Zn_Tnp_IS1 PF03811.13 OAG45010.1 - 0.11 12.2 0.2 0.27 11.0 0.2 1.6 1 0 0 1 1 1 0 InsA N-terminal domain 2-Hacid_dh_C PF02826.19 OAG45010.1 - 0.12 11.7 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DDHD PF02862.17 OAG45011.1 - 0.082 13.1 6.8 0.11 12.7 6.8 1.4 1 0 0 1 1 1 0 DDHD domain Hid1 PF12722.7 OAG45011.1 - 0.15 10.2 8.4 0.17 10.0 8.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Macoilin PF09726.9 OAG45011.1 - 0.45 9.0 18.0 0.56 8.7 18.0 1.1 1 0 0 1 1 1 0 Macoilin family Presenilin PF01080.17 OAG45011.1 - 1.1 8.0 10.6 1.5 7.5 10.6 1.2 1 0 0 1 1 1 0 Presenilin DUF572 PF04502.13 OAG45011.1 - 1.3 8.6 11.1 1.5 8.4 11.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) GREB1 PF15782.5 OAG45011.1 - 2 5.5 15.1 2.2 5.3 15.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Plasmodium_Vir PF05795.11 OAG45011.1 - 3.1 7.1 10.5 4 6.8 10.5 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein SLC12 PF03522.15 OAG45011.1 - 3.4 6.6 7.1 4.3 6.3 7.1 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Apt1 PF10351.9 OAG45011.1 - 3.8 6.3 20.8 5.1 5.8 20.8 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Tmemb_cc2 PF10267.9 OAG45011.1 - 7.7 5.5 13.7 9.6 5.2 13.7 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Arrestin_C PF02752.22 OAG45013.1 - 5.9e-14 52.7 0.0 5.6e-13 49.5 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Pro_isomerase PF00160.21 OAG45014.1 - 1.6e-45 155.2 0.0 1.8e-45 155.0 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SH3_1 PF00018.28 OAG45015.1 - 3.1e-05 23.5 0.0 7e-05 22.4 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 OAG45015.1 - 0.012 15.5 0.2 0.1 12.5 0.0 2.4 2 0 0 2 2 2 0 Variant SH3 domain Pkinase PF00069.25 OAG45016.1 - 2.1e-38 132.2 0.0 3.5e-38 131.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG45016.1 - 4.3e-23 81.9 0.0 8.9e-18 64.5 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAG45016.1 - 0.065 12.0 0.0 0.12 11.1 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Abhydrolase_3 PF07859.13 OAG45017.1 - 1.1e-61 208.4 0.2 1.6e-61 207.8 0.2 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 OAG45017.1 - 0.00096 18.1 0.0 0.0091 14.9 0.0 1.9 2 0 0 2 2 2 1 Carboxylesterase family Say1_Mug180 PF10340.9 OAG45017.1 - 0.023 13.6 0.0 0.039 12.8 0.0 1.3 1 1 0 1 1 1 0 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 OAG45017.1 - 0.029 13.8 0.0 0.091 12.2 0.0 1.7 1 1 0 1 1 1 0 Prolyl oligopeptidase family Esterase_phd PF10503.9 OAG45017.1 - 0.23 10.9 1.2 9.6 5.6 1.3 2.3 1 1 0 1 1 1 0 Esterase PHB depolymerase EMP24_GP25L PF01105.24 OAG45018.1 - 1.3e-49 168.6 0.1 1.5e-49 168.4 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD MFS_1 PF07690.16 OAG45019.1 - 8.1e-45 153.3 43.8 8.1e-45 153.3 43.8 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 OAG45019.1 - 9.3e-10 37.5 24.7 1.7e-09 36.7 24.7 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 OAG45019.1 - 0.0013 17.1 3.9 0.0013 17.1 3.9 2.4 2 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family Zn_clus PF00172.18 OAG45020.1 - 9.3e-08 32.1 7.5 1.9e-07 31.1 7.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.25 OAG45021.1 - 8.6e-31 106.9 0.4 2.4e-29 102.2 0.4 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG45021.1 - 1.2e-22 80.7 0.1 9.5e-22 77.7 0.1 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG45021.1 - 1.9e-10 41.0 0.1 2.6e-10 40.5 0.1 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 OAG45021.1 - 2.2e-05 24.4 0.0 3e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAG45021.1 - 0.00061 19.3 0.0 0.00069 19.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 OAG45021.1 - 0.00072 19.8 0.1 0.0013 19.0 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Polysacc_synt_2 PF02719.15 OAG45021.1 - 0.011 14.9 0.0 0.017 14.3 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Abhydrolase_2 PF02230.16 OAG45022.1 - 3.2e-10 40.2 0.0 2.7e-08 33.9 0.0 2.3 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 OAG45022.1 - 7.6e-09 35.3 0.1 0.0013 18.3 0.1 2.3 1 1 1 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 OAG45022.1 - 1.5e-07 30.9 0.1 7e-05 22.2 0.0 2.6 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Esterase_phd PF10503.9 OAG45022.1 - 3.2e-07 30.1 0.1 0.00034 20.2 0.0 3.2 3 1 1 4 4 4 2 Esterase PHB depolymerase DLH PF01738.18 OAG45022.1 - 1.6e-06 27.8 0.0 3e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Dienelactone hydrolase family Esterase PF00756.20 OAG45022.1 - 1.2e-05 25.1 0.0 0.00078 19.2 0.0 2.2 2 0 0 2 2 2 1 Putative esterase Abhydrolase_6 PF12697.7 OAG45022.1 - 0.0047 17.6 1.6 0.0047 17.6 1.6 2.3 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAG45022.1 - 0.076 12.6 0.0 0.83 9.2 0.0 2.3 1 1 1 2 2 2 0 alpha/beta hydrolase fold Snf7 PF03357.21 OAG45023.1 - 1.2e-30 106.4 13.8 1.2e-30 106.4 13.8 1.6 1 1 1 2 2 2 1 Snf7 MR_MLE_N PF02746.16 OAG45023.1 - 0.01 16.0 0.1 0.021 15.0 0.1 1.4 1 0 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain CLP_protease PF00574.23 OAG45023.1 - 2.1 8.2 6.2 4.2 7.2 0.3 2.8 1 1 2 3 3 3 0 Clp protease PITH PF06201.13 OAG45024.1 - 7.4e-43 146.4 0.0 9.4e-43 146.0 0.0 1.1 1 0 0 1 1 1 1 PITH domain Cu-oxidase_2 PF07731.14 OAG45025.1 - 0.054 13.2 0.5 0.16 11.7 0.5 1.7 1 0 0 1 1 1 0 Multicopper oxidase DUF647 PF04884.14 OAG45027.1 - 8.8e-89 297.3 0.1 1.2e-88 296.8 0.1 1.1 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis DUF5377 PF17347.2 OAG45027.1 - 0.011 16.1 0.0 0.027 14.8 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5377) ThaI PF15514.6 OAG45027.1 - 0.17 11.5 0.0 0.31 10.7 0.0 1.4 1 0 0 1 1 1 0 Restriction endonuclease ThaI RGS PF00615.19 OAG45028.1 - 6.8e-10 39.2 0.0 9.8e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain S36_mt PF10937.8 OAG45030.1 - 2.5e-13 51.6 0.0 2.5e-13 51.6 0.0 2.3 1 1 1 2 2 2 1 Ribosomal protein S36, mitochondrial Tom5 PF10642.9 OAG45030.1 - 0.084 12.9 0.5 0.96 9.5 0.5 2.8 1 0 0 1 1 1 0 Mitochondrial import receptor subunit or translocase CDC27 PF09507.10 OAG45030.1 - 0.38 10.1 45.9 0.5 9.7 45.9 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 SAPS PF04499.15 OAG45030.1 - 5.4 5.7 28.5 5.7 5.6 28.5 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Hid1 PF12722.7 OAG45030.1 - 7.9 4.5 26.9 8.1 4.4 26.9 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Med18 PF09637.10 OAG45031.1 - 5.1e-43 147.7 0.0 5.8e-43 147.5 0.0 1.0 1 0 0 1 1 1 1 Med18 protein PNK3P PF08645.11 OAG45032.1 - 3.7e-54 182.8 0.0 5.6e-54 182.2 0.0 1.3 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.6 OAG45032.1 - 1.9e-11 44.3 0.0 5.5e-11 42.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 OAG45032.1 - 0.046 13.6 0.0 0.086 12.8 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain RsgA_GTPase PF03193.16 OAG45032.1 - 0.084 12.8 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA PF00004.29 OAG45032.1 - 0.12 12.8 0.1 0.28 11.6 0.0 1.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF3439 PF11921.8 OAG45033.1 - 0.094 12.7 0.3 0.094 12.7 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Peptidase_S9 PF00326.21 OAG45034.1 - 2.9e-44 151.1 0.0 4.7e-44 150.4 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 OAG45034.1 - 1.3e-11 44.5 1.0 6.1e-11 42.3 0.2 2.3 2 1 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S15 PF02129.18 OAG45034.1 - 7.8e-10 38.8 0.1 4e-06 26.6 0.5 2.4 2 0 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.20 OAG45034.1 - 1.3e-08 34.8 0.3 0.00076 19.2 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAG45034.1 - 3.4e-08 33.0 0.0 0.0019 17.5 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 PD40 PF07676.12 OAG45034.1 - 5.5e-07 29.4 3.0 0.013 15.4 0.2 2.5 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat BAAT_C PF08840.11 OAG45034.1 - 4.6e-06 26.7 0.0 9.1e-05 22.5 0.0 2.2 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_3 PF07859.13 OAG45034.1 - 8.9e-06 25.7 0.2 0.00013 21.9 0.2 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold AXE1 PF05448.12 OAG45034.1 - 0.0001 21.1 0.0 0.00021 20.1 0.0 1.4 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.16 OAG45034.1 - 0.0018 18.1 0.0 1.6 8.5 0.0 2.3 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Esterase_phd PF10503.9 OAG45034.1 - 0.0055 16.2 2.0 0.2 11.1 0.4 2.5 2 1 0 2 2 2 1 Esterase PHB depolymerase Esterase PF00756.20 OAG45034.1 - 0.02 14.6 0.1 0.075 12.7 0.0 1.8 2 0 0 2 2 2 0 Putative esterase COesterase PF00135.28 OAG45034.1 - 0.02 13.8 0.0 0.029 13.3 0.0 1.1 1 0 0 1 1 1 0 Carboxylesterase family DUF1749 PF08538.10 OAG45034.1 - 0.02 14.0 0.0 0.12 11.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.7 OAG45034.1 - 0.055 14.1 7.8 0.041 14.5 3.9 2.5 2 1 0 2 2 2 0 Alpha/beta hydrolase family FSH1 PF03959.13 OAG45034.1 - 0.058 13.0 0.0 0.16 11.6 0.0 1.7 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_4 PF08386.10 OAG45034.1 - 0.086 13.0 0.0 0.23 11.6 0.0 1.7 1 0 0 1 1 1 0 TAP-like protein LIP PF03583.14 OAG45034.1 - 0.16 11.3 2.3 3.3 6.9 1.5 2.2 2 0 0 2 2 2 0 Secretory lipase Rad51 PF08423.11 OAG45035.1 - 5.2e-41 140.6 0.0 1.7e-40 138.9 0.0 1.7 1 1 0 1 1 1 1 Rad51 AAA_25 PF13481.6 OAG45035.1 - 2.1e-05 24.2 0.0 4.6e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 OAG45035.1 - 8.6e-05 22.0 0.5 0.018 14.4 0.1 2.9 2 1 0 2 2 2 1 DnaB-like helicase C terminal domain ATPase PF06745.13 OAG45035.1 - 0.00049 19.5 0.2 0.0039 16.6 0.1 2.4 2 1 0 2 2 2 1 KaiC RecA PF00154.21 OAG45035.1 - 0.0049 16.4 0.4 0.41 10.1 0.0 2.2 2 0 0 2 2 2 2 recA bacterial DNA recombination protein HU-CCDC81_euk_2 PF18289.1 OAG45035.1 - 0.17 12.1 0.0 0.33 11.2 0.0 1.4 1 0 0 1 1 1 0 CCDC81 eukaryotic HU domain 2 Cu_amine_oxid PF01179.20 OAG45036.1 - 1.5e-165 551.1 0.0 1.8e-165 550.8 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.16 OAG45036.1 - 0.00023 21.4 0.2 0.00059 20.0 0.2 1.7 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.16 OAG45036.1 - 0.058 13.8 0.0 0.14 12.6 0.0 1.6 1 0 0 1 1 1 0 Copper amine oxidase, N3 domain WLM PF08325.10 OAG45037.1 - 2.4e-50 171.3 0.1 3.4e-50 170.8 0.1 1.2 1 0 0 1 1 1 1 WLM domain DUF45 PF01863.17 OAG45037.1 - 0.067 13.2 0.2 0.14 12.2 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF45 6PF2K PF01591.18 OAG45038.1 - 2.6e-66 223.1 0.2 7.6e-47 159.5 0.2 2.2 2 0 0 2 2 2 2 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 OAG45038.1 - 4e-28 98.4 0.0 9.8e-21 74.3 0.0 2.7 3 0 0 3 3 3 2 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 OAG45038.1 - 6.8e-05 23.1 0.0 0.46 10.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain KTI12 PF08433.10 OAG45038.1 - 0.045 13.2 0.0 0.81 9.1 0.0 2.2 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Na_H_Exchanger PF00999.21 OAG45039.1 - 2.7e-46 158.1 17.6 3.6e-46 157.7 17.6 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Tetraspanin PF00335.20 OAG45039.1 - 3.3 7.4 7.0 14 5.3 1.3 3.0 3 0 0 3 3 3 0 Tetraspanin family Cauli_VI PF01693.16 OAG45040.1 - 1.3e-38 131.0 7.4 3.2e-19 68.9 0.6 2.6 2 0 0 2 2 2 2 Caulimovirus viroplasmin RNase_H PF00075.24 OAG45040.1 - 8.8e-31 107.0 7.1 1.2e-27 96.9 0.4 2.9 4 0 0 4 4 4 2 RNase H RVT_3 PF13456.6 OAG45040.1 - 0.012 15.4 0.0 0.034 13.9 0.0 1.7 1 0 0 1 1 1 0 Reverse transcriptase-like CAML PF14963.6 OAG45040.1 - 0.38 10.8 1.3 0.88 9.6 1.3 1.5 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand MFS_1 PF07690.16 OAG45041.1 - 1.6e-42 145.7 50.5 7.3e-40 137.0 52.8 3.0 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG45041.1 - 2.1e-07 30.2 9.9 2.1e-07 30.2 9.9 2.6 2 1 0 2 2 2 2 Sugar (and other) transporter p450 PF00067.22 OAG45042.1 - 4.8e-50 170.6 0.0 6e-50 170.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FMN_dh PF01070.18 OAG45043.1 - 5e-104 348.1 0.0 6e-104 347.8 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 OAG45043.1 - 3.1e-17 62.5 0.0 6.5e-17 61.4 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 OAG45043.1 - 3.9e-08 32.8 0.2 6.3e-08 32.1 0.2 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 OAG45043.1 - 1.9e-06 27.1 0.0 1.2e-05 24.5 0.1 1.9 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.21 OAG45043.1 - 0.013 15.0 0.0 0.032 13.7 0.0 1.6 1 0 0 1 1 1 0 Histidine biosynthesis protein NMO PF03060.15 OAG45043.1 - 0.013 14.9 1.5 0.025 14.0 1.5 1.4 1 0 0 1 1 1 0 Nitronate monooxygenase DHO_dh PF01180.21 OAG45043.1 - 0.029 13.6 0.1 0.05 12.8 0.1 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase ThiG PF05690.14 OAG45043.1 - 0.06 12.7 0.2 0.21 10.9 0.1 1.8 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG Ribul_P_3_epim PF00834.19 OAG45043.1 - 0.12 11.8 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family RNase_HII PF01351.18 OAG45044.1 - 1.7e-48 165.1 0.0 3.5e-48 164.1 0.0 1.5 1 1 0 1 1 1 1 Ribonuclease HII CENP-C_C PF11699.8 OAG45045.1 - 4.7e-20 71.6 0.0 1.1e-19 70.4 0.0 1.6 1 0 0 1 1 1 1 Mif2/CENP-C like Mif2_N PF15624.6 OAG45045.1 - 1.8e-18 67.5 10.8 1.8e-18 67.5 10.8 3.5 3 1 0 3 3 3 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Cupin_2 PF07883.11 OAG45045.1 - 0.0076 16.0 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 OAG45045.1 - 0.0077 15.9 0.1 0.02 14.6 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF861) THEG4 PF15834.5 OAG45045.1 - 0.034 14.1 0.2 0.58 10.1 0.0 2.7 2 0 0 2 2 2 0 Testis highly expressed protein 4 CAP_GLY PF01302.25 OAG45046.1 - 3.8e-21 74.9 2.4 6.5e-21 74.1 2.4 1.4 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.6 OAG45046.1 - 6.7e-14 52.1 0.0 1.3e-13 51.2 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.23 OAG45046.1 - 0.00098 18.8 0.0 0.0021 17.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family AMP-binding PF00501.28 OAG45047.1 - 3.4e-73 246.7 0.0 4.2e-73 246.3 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG45047.1 - 2e-13 51.1 0.0 1.3e-12 48.5 0.0 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain SRF-TF PF00319.18 OAG45048.1 - 0.16 11.5 0.0 1.4 8.5 0.0 2.4 3 0 0 3 3 3 0 SRF-type transcription factor (DNA-binding and dimerisation domain) ATP_synth_reg PF14960.6 OAG45048.1 - 0.26 10.8 1.6 0.77 9.3 0.0 2.5 3 0 0 3 3 3 0 ATP synthase regulation PhoLip_ATPase_C PF16212.5 OAG45048.1 - 5 6.8 8.9 0.29 10.9 2.9 1.8 1 1 1 2 2 2 0 Phospholipid-translocating P-type ATPase C-terminal RR_TM4-6 PF06459.12 OAG45049.1 - 3.8 7.3 5.5 6.5 6.5 5.5 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SAE2 PF08573.10 OAG45050.1 - 6.6e-23 81.9 0.0 6.6e-23 81.9 0.0 3.4 3 1 0 3 3 3 1 DNA repair protein endonuclease SAE2/CtIP C-terminus HALZ PF02183.18 OAG45050.1 - 0.004 17.3 2.8 0.004 17.3 2.8 2.5 2 0 0 2 2 2 1 Homeobox associated leucine zipper FapA PF03961.13 OAG45050.1 - 0.008 14.8 5.8 0.013 14.1 5.8 1.2 1 0 0 1 1 1 1 Flagellar Assembly Protein A CENP-H PF05837.12 OAG45050.1 - 0.023 15.1 11.3 0.037 14.4 8.4 2.4 2 0 0 2 2 2 0 Centromere protein H (CENP-H) DUF4407 PF14362.6 OAG45050.1 - 0.48 9.7 9.8 0.62 9.4 5.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) FUSC PF04632.12 OAG45050.1 - 0.71 8.3 3.0 1.2 7.6 3.0 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family YabA PF06156.13 OAG45050.1 - 0.73 10.5 13.9 45 4.8 11.0 3.3 2 1 0 2 2 2 0 Initiation control protein YabA TMPIT PF07851.13 OAG45050.1 - 5.6 6.1 4.4 9.6 5.3 4.4 1.3 1 0 0 1 1 1 0 TMPIT-like protein APG6_N PF17675.1 OAG45050.1 - 8.8 6.9 22.9 0.089 13.3 12.5 2.2 2 0 0 2 2 2 0 Apg6 coiled-coil region Cnn_1N PF07989.11 OAG45050.1 - 9.5 6.5 18.5 0.091 12.9 9.4 2.2 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 F-box PF00646.33 OAG45051.1 - 1.7e-07 31.0 1.6 3.4e-07 30.0 1.6 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 OAG45051.1 - 3.2e-07 30.1 0.1 6.4e-07 29.2 0.1 1.5 1 0 0 1 1 1 1 F-box-like zf-CCHC PF00098.23 OAG45052.1 - 2.3e-42 141.2 50.4 6.5e-09 35.5 2.7 6.2 6 0 0 6 6 6 6 Zinc knuckle zf-CCHC_3 PF13917.6 OAG45052.1 - 1.2e-07 31.6 34.7 0.067 13.2 0.5 6.1 3 2 3 6 6 6 6 Zinc knuckle zf-CCHC_4 PF14392.6 OAG45052.1 - 1.2e-06 28.2 29.6 0.15 11.8 1.5 6.0 6 0 0 6 6 6 5 Zinc knuckle zf-CCHC_5 PF14787.6 OAG45052.1 - 0.017 14.8 34.9 0.19 11.4 2.1 6.1 6 0 0 6 6 6 0 GAG-polyprotein viral zinc-finger zf-CCHC_2 PF13696.6 OAG45052.1 - 0.041 13.7 2.4 0.041 13.7 2.4 5.9 6 1 0 6 6 6 0 Zinc knuckle NinD PF17466.2 OAG45052.1 - 0.063 13.4 2.3 0.063 13.4 2.3 4.3 5 0 0 5 5 5 0 Family of unknown function zf-CCHC_6 PF15288.6 OAG45052.1 - 0.11 12.4 40.9 0.21 11.4 0.8 6.0 5 1 1 6 6 6 0 Zinc knuckle DUF4079 PF13301.6 OAG45053.1 - 0.00027 21.1 5.6 0.35 11.0 0.2 3.2 2 1 1 3 3 3 3 Protein of unknown function (DUF4079) MIG-14_Wnt-bd PF06664.12 OAG45053.1 - 0.28 10.4 3.2 3.1 7.0 0.1 2.1 2 0 0 2 2 2 0 Wnt-binding factor required for Wnt secretion DUF1295 PF06966.12 OAG45054.1 - 1.8e-14 53.8 0.3 2.9e-14 53.2 0.2 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 OAG45054.1 - 4.5e-05 23.5 0.2 6.1e-05 23.0 0.2 1.3 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.13 OAG45054.1 - 0.00029 21.2 0.8 0.0016 18.8 0.4 2.2 1 1 1 2 2 2 1 Phospholipid methyltransferase NnrU PF07298.11 OAG45054.1 - 0.0007 19.2 0.6 0.0016 18.0 0.1 1.7 1 1 1 2 2 2 1 NnrU protein ERG4_ERG24 PF01222.17 OAG45054.1 - 0.00072 18.4 1.8 0.002 17.0 1.5 1.8 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF423 PF04241.15 OAG45054.1 - 0.012 15.8 0.3 0.037 14.2 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF423) ICMT PF04140.14 OAG45054.1 - 0.069 13.6 0.0 0.13 12.7 0.0 1.6 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family adh_short_C2 PF13561.6 OAG45055.1 - 1.1e-30 107.0 0.0 1e-25 90.7 0.0 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG45055.1 - 9.6e-24 83.9 0.0 7.6e-22 77.7 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 OAG45055.1 - 6.8e-08 32.3 0.0 4e-07 29.7 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OAG45055.1 - 1.6e-07 30.6 0.0 2.3e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 OAG45055.1 - 0.00011 22.1 0.0 0.00016 21.6 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 OAG45055.1 - 0.00069 19.1 0.0 0.0024 17.3 0.0 1.9 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 OAG45055.1 - 0.0086 15.6 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.17 OAG45055.1 - 0.012 14.8 0.0 0.019 14.0 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain KR PF08659.10 OAG45055.1 - 0.024 14.5 2.6 8.6 6.2 2.6 3.2 1 1 0 1 1 1 0 KR domain Polysacc_synt_2 PF02719.15 OAG45055.1 - 0.037 13.2 0.1 0.072 12.2 0.1 1.5 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein TIG PF01833.24 OAG45056.1 - 2e-10 40.6 0.2 6.3e-10 39.0 0.2 1.9 1 0 0 1 1 1 1 IPT/TIG domain Methyltransf_11 PF08241.12 OAG45056.1 - 5e-10 39.9 0.0 1.2e-09 38.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG45056.1 - 3.6e-09 37.2 0.0 1.3e-08 35.4 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain Ank_4 PF13637.6 OAG45056.1 - 3e-08 34.0 0.5 8.4e-08 32.6 0.5 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 OAG45056.1 - 6.8e-08 32.6 5.7 0.0012 19.2 0.2 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 OAG45056.1 - 4.6e-07 30.3 0.0 9.7e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OAG45056.1 - 4.4e-06 26.6 1.1 0.2 12.3 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Methyltransf_23 PF13489.6 OAG45056.1 - 2.9e-05 24.0 0.0 0.00013 21.9 0.0 2.1 3 0 0 3 3 2 1 Methyltransferase domain Ank_5 PF13857.6 OAG45056.1 - 4.8e-05 23.6 0.1 0.00012 22.3 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Methyltransf_12 PF08242.12 OAG45056.1 - 0.0036 18.0 0.0 0.0099 16.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG45056.1 - 0.03 14.1 0.0 0.06 13.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain RHD_dimer PF16179.5 OAG45056.1 - 0.07 13.2 0.0 0.18 11.8 0.0 1.7 1 0 0 1 1 1 0 Rel homology dimerisation domain ASXH PF13919.6 OAG45057.1 - 2.7e-18 66.3 0.0 3.8e-18 65.9 0.0 1.1 1 0 0 1 1 1 1 Asx homology domain Pex16 PF08610.10 OAG45058.1 - 2.3e-128 428.0 0.7 2.6e-128 427.8 0.7 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) BUD22 PF09073.10 OAG45060.1 - 1.2 8.4 9.3 33 3.7 0.0 2.3 2 0 0 2 2 2 0 BUD22 Vip3A_N PF12495.8 OAG45061.1 - 0.0082 16.1 0.8 0.016 15.2 0.8 1.4 1 0 0 1 1 1 1 Vegetative insecticide protein 3A N terminal Amidohydro_1 PF01979.20 OAG45061.1 - 0.14 11.5 1.8 0.26 10.6 1.8 1.4 1 0 0 1 1 1 0 Amidohydrolase family AAA_23 PF13476.6 OAG45061.1 - 0.41 11.1 5.6 0.71 10.3 5.6 1.4 1 0 0 1 1 1 0 AAA domain IZUMO PF15005.6 OAG45061.1 - 0.65 10.5 2.5 13 6.3 3.4 2.2 2 0 0 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated CBFD_NFYB_HMF PF00808.23 OAG45062.1 - 0.00035 20.8 0.2 0.00049 20.3 0.2 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-W PF15510.6 OAG45062.1 - 0.0035 17.5 0.0 0.0049 17.1 0.0 1.2 1 0 0 1 1 1 1 CENP-W protein Phage_TAC_1 PF06222.11 OAG45063.1 - 0.15 11.8 0.0 0.7 9.7 0.0 2.0 2 0 0 2 2 2 0 Phage tail assembly chaperone HEAT_2 PF13646.6 OAG45064.1 - 0.00011 22.5 8.7 0.00063 20.1 0.4 5.3 5 2 0 5 5 5 1 HEAT repeats Arm PF00514.23 OAG45064.1 - 0.0007 19.6 20.1 0.084 13.0 0.1 8.1 11 0 0 11 11 11 2 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 OAG45064.1 - 0.0041 17.6 10.2 0.84 10.2 0.3 6.8 7 0 0 7 7 7 1 HEAT-like repeat DUF3535 PF12054.8 OAG45064.1 - 0.009 15.3 0.8 0.019 14.2 0.8 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3535) WAPL PF07814.13 OAG45064.1 - 0.051 12.4 1.3 0.32 9.7 0.1 2.7 3 1 0 3 3 3 0 Wings apart-like protein regulation of heterochromatin V-ATPase_H_C PF11698.8 OAG45064.1 - 0.081 13.0 0.1 7.9 6.6 0.0 3.0 2 1 1 3 3 3 0 V-ATPase subunit H HEAT PF02985.22 OAG45064.1 - 0.1 12.9 18.3 0.18 12.1 0.0 7.2 8 0 0 8 8 8 0 HEAT repeat DUF3361 PF11841.8 OAG45064.1 - 0.12 12.3 1.4 0.41 10.6 1.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3361) Cyclin PF08613.11 OAG45065.1 - 4.6e-31 108.4 0.0 8.4e-31 107.5 0.0 1.5 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 OAG45065.1 - 2.6e-05 23.9 0.0 4.4e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain CMV_1a PF12467.8 OAG45065.1 - 0.079 13.3 0.5 4.1 7.7 0.3 2.3 2 0 0 2 2 2 0 Cucumber mosaic virus 1a protein family Chromo PF00385.24 OAG45066.1 - 3.3e-11 42.9 0.9 9e-11 41.5 0.9 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF1604 PF07713.13 OAG45066.1 - 0.15 11.9 0.6 0.77 9.6 0.6 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1604) Topoisom_I_N PF02919.15 OAG45066.1 - 1.1 8.7 4.6 1.7 8.1 2.5 2.3 2 0 0 2 2 2 0 Eukaryotic DNA topoisomerase I, DNA binding fragment Ras PF00071.22 OAG45067.1 - 3.3e-63 212.1 0.3 3.9e-63 211.9 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAG45067.1 - 2.7e-35 121.2 0.2 3.8e-35 120.7 0.2 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAG45067.1 - 2.8e-13 49.7 0.1 3.7e-13 49.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OAG45067.1 - 5.6e-08 32.9 0.1 8.6e-08 32.3 0.1 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OAG45067.1 - 8.7e-05 22.5 0.2 0.014 15.3 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 OAG45067.1 - 0.00012 21.7 0.2 0.00057 19.5 0.1 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OAG45067.1 - 0.00048 19.5 0.1 0.00076 18.9 0.1 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 OAG45067.1 - 0.0043 17.3 0.0 0.032 14.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain SRPRB PF09439.10 OAG45067.1 - 0.016 14.6 0.0 0.024 14.0 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_14 PF13173.6 OAG45067.1 - 0.018 15.1 0.1 0.061 13.4 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 OAG45067.1 - 0.019 15.3 0.1 0.032 14.6 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 OAG45067.1 - 0.023 15.2 0.1 0.032 14.7 0.1 1.5 1 1 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 OAG45067.1 - 0.024 14.4 0.1 0.06 13.1 0.1 1.7 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 OAG45067.1 - 0.041 13.3 0.0 0.16 11.3 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein FeoB_N PF02421.18 OAG45067.1 - 0.089 12.3 0.1 0.22 11.0 0.0 1.6 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_7 PF12775.7 OAG45067.1 - 0.092 12.3 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region SpoIIID PF12116.8 OAG45067.1 - 0.13 12.4 0.1 2.4 8.3 0.0 2.2 2 0 0 2 2 2 0 Stage III sporulation protein D AAA_21 PF13304.6 OAG45067.1 - 0.14 12.0 0.6 0.23 11.2 0.4 1.5 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Pyr_redox_2 PF07992.14 OAG45068.1 - 3.4e-15 56.1 0.0 6.6e-13 48.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG45068.1 - 8.1e-15 54.9 0.0 2.3e-14 53.4 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 OAG45068.1 - 1e-14 53.9 0.0 4.9e-14 51.6 0.0 1.8 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 OAG45068.1 - 2.9e-06 26.6 0.2 7.5e-06 25.3 0.0 1.7 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 OAG45068.1 - 5.6e-05 23.3 0.9 0.00018 21.7 0.3 2.2 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAG45068.1 - 0.00072 19.2 0.4 0.23 11.0 0.0 2.7 2 1 0 3 3 3 2 FAD dependent oxidoreductase Shikimate_DH PF01488.20 OAG45068.1 - 0.016 15.2 0.1 0.16 12.1 0.0 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Lycopene_cycl PF05834.12 OAG45068.1 - 0.03 13.4 0.1 0.41 9.6 0.1 2.4 3 0 0 3 3 3 0 Lycopene cyclase protein FAD_binding_2 PF00890.24 OAG45068.1 - 0.079 12.0 0.4 0.17 10.9 0.2 1.6 2 0 0 2 2 2 0 FAD binding domain GSG-1 PF07803.11 OAG45068.1 - 0.14 12.1 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 GSG1-like protein GIDA PF01134.22 OAG45068.1 - 0.15 11.1 0.0 1.7 7.6 0.0 2.3 3 0 0 3 3 3 0 Glucose inhibited division protein A HI0933_like PF03486.14 OAG45068.1 - 0.18 10.5 0.6 2.9 6.5 0.0 2.3 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox PF00070.27 OAG45068.1 - 0.26 11.9 3.8 9.7 6.8 0.0 3.6 4 0 0 4 4 4 0 Pyridine nucleotide-disulphide oxidoreductase F-box-like PF12937.7 OAG45069.1 - 0.00053 19.8 0.7 0.00053 19.8 0.7 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 OAG45069.1 - 0.037 13.9 0.6 0.092 12.6 0.6 1.7 1 0 0 1 1 1 0 F-box domain Aldo_ket_red PF00248.21 OAG45070.1 - 6.1e-48 163.5 0.0 7e-48 163.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Brix PF04427.18 OAG45071.1 - 2.7e-33 115.7 0.0 3.4e-33 115.4 0.0 1.1 1 0 0 1 1 1 1 Brix domain Mak10 PF04112.13 OAG45072.1 - 6.6e-22 77.8 0.2 1.9e-19 69.8 0.2 2.5 1 1 1 2 2 2 2 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase ATP-synt_Eps PF04627.13 OAG45072.1 - 2e-21 75.7 0.7 7.8e-21 73.8 0.9 2.0 2 0 0 2 2 2 1 Mitochondrial ATP synthase epsilon chain DUF1651 PF07864.11 OAG45072.1 - 0.012 15.9 0.0 0.047 14.0 0.0 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1651) RNA_pol_Rpc82 PF05645.13 OAG45073.1 - 3.6e-07 30.2 0.0 0.00011 22.1 0.0 3.0 2 1 0 2 2 2 2 RNA polymerase III subunit RPC82 TFIIE_alpha PF02002.17 OAG45073.1 - 0.00016 21.5 1.1 0.00029 20.6 0.5 1.7 2 0 0 2 2 2 1 TFIIE alpha subunit HTH_9 PF08221.11 OAG45073.1 - 0.14 12.3 0.7 5.6 7.2 0.0 2.8 3 0 0 3 3 3 0 RNA polymerase III subunit RPC82 helix-turn-helix domain Peptidase_M16 PF00675.20 OAG45074.1 - 1.7e-15 57.3 0.0 3e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 OAG45074.1 - 1.3e-10 41.6 0.0 2.3e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase M16 inactive domain PALB2_WD40 PF16756.5 OAG45074.1 - 0.093 11.6 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Partner and localizer of BRCA2 WD40 domain UPF0253 PF06786.12 OAG45074.1 - 0.67 10.3 2.5 1.2 9.4 1.5 2.0 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0253) FMO-like PF00743.19 OAG45075.1 - 3.1e-17 62.2 0.1 2e-14 52.9 0.0 2.3 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 OAG45075.1 - 1.5e-13 50.7 0.0 1.1e-11 44.6 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG45075.1 - 2e-13 50.3 0.0 5.8e-12 45.5 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG45075.1 - 5.4e-09 35.7 0.1 1.1e-07 31.4 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 OAG45075.1 - 4.9e-05 23.4 0.2 0.034 14.2 0.2 3.5 3 1 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 OAG45075.1 - 6.6e-05 23.1 0.0 0.00072 19.7 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 OAG45075.1 - 0.0032 18.0 0.1 1.5 9.4 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 OAG45075.1 - 0.024 15.1 0.0 7.1 7.1 0.0 2.6 2 0 0 2 2 2 0 Putative NAD(P)-binding Shikimate_DH PF01488.20 OAG45075.1 - 0.15 12.1 0.2 0.92 9.6 0.0 2.2 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase DUF1902 PF08972.11 OAG45075.1 - 0.16 12.0 1.2 0.37 10.8 1.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1902) Flavodoxin_1 PF00258.25 OAG45075.1 - 0.16 12.2 0.0 0.65 10.2 0.0 2.0 2 0 0 2 2 2 0 Flavodoxin LRR_8 PF13855.6 OAG45076.1 - 0.33 10.7 3.5 38 4.1 0.2 3.8 3 0 0 3 3 3 0 Leucine rich repeat BUD22 PF09073.10 OAG45076.1 - 0.6 9.4 10.9 1.2 8.4 10.9 1.4 1 0 0 1 1 1 0 BUD22 LRR_4 PF12799.7 OAG45076.1 - 0.93 10.0 9.0 8.6 6.9 0.7 5.1 4 1 3 7 7 7 0 Leucine Rich repeats (2 copies) Chs7 PF12271.8 OAG45077.1 - 1e-110 369.7 8.2 1.1e-110 369.5 8.2 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone YvrJ PF12841.7 OAG45077.1 - 0.064 12.8 0.1 0.14 11.7 0.1 1.5 1 0 0 1 1 1 0 YvrJ protein family DUF1129 PF06570.11 OAG45077.1 - 0.32 10.5 13.9 0.023 14.2 6.9 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1129) Cytochrom_B_C PF00032.17 OAG45077.1 - 0.7 10.2 7.2 0.32 11.3 0.3 2.8 2 2 1 3 3 3 0 Cytochrome b(C-terminal)/b6/petD V1R PF03402.14 OAG45077.1 - 1.3 8.6 6.8 0.12 11.9 1.3 2.1 3 1 0 3 3 3 0 Vomeronasal organ pheromone receptor family, V1R Ge1_WD40 PF16529.5 OAG45079.1 - 0.0029 16.6 0.0 0.012 14.6 0.0 1.9 1 1 0 1 1 1 1 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF445 PF04286.12 OAG45079.1 - 0.83 9.4 11.9 0.14 11.9 4.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF445) FAD_binding_4 PF01565.23 OAG45080.1 - 3.8e-05 23.5 0.0 5.3e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 OAG45081.1 - 0.0052 15.9 3.3 0.079 12.0 3.1 1.9 1 1 1 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 OAG45081.1 - 0.078 12.2 0.5 0.082 12.1 0.5 1.2 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.16 OAG45082.1 - 2.5e-22 79.3 29.9 3.5e-22 78.8 29.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 OAG45082.1 - 0.0033 15.9 3.7 0.005 15.3 3.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2235 PF09994.9 OAG45083.1 - 3.1e-27 95.7 0.0 3.5e-27 95.5 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_2 PF02230.16 OAG45083.1 - 0.12 12.2 0.1 0.26 11.1 0.1 1.5 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase PhyH PF05721.13 OAG45085.1 - 7.4e-23 81.9 0.0 1e-22 81.5 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) HGWP PF03578.15 OAG45085.1 - 0.048 13.2 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 HGWP repeat Spc7 PF08317.11 OAG45086.1 - 0.047 12.6 47.3 0.34 9.7 5.2 4.5 1 1 2 4 4 4 0 Spc7 kinetochore protein CorA PF01544.18 OAG45086.1 - 0.26 10.5 23.5 1.3 8.3 6.9 3.9 2 1 2 4 4 4 0 CorA-like Mg2+ transporter protein Baculo_PEP_C PF04513.12 OAG45086.1 - 0.32 11.0 26.7 4.8 7.2 0.0 5.4 2 1 4 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus Tropomyosin_1 PF12718.7 OAG45086.1 - 2.5 8.3 53.3 0.76 9.9 13.7 5.9 3 1 3 6 6 6 0 Tropomyosin like DASH_Dam1 PF08653.10 OAG45086.1 - 5.5 6.9 10.1 6.5 6.6 0.1 4.7 6 0 0 6 6 6 0 DASH complex subunit Dam1 DUF1664 PF07889.12 OAG45086.1 - 7.5 6.6 32.0 1.9 8.6 1.1 5.6 2 1 2 5 5 5 0 Protein of unknown function (DUF1664) TIP49 PF06068.13 OAG45087.1 - 1.1e-152 508.4 1.8 1.6e-152 507.8 1.8 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 OAG45087.1 - 9.3e-21 73.7 1.7 1.7e-20 72.9 0.4 2.2 3 0 0 3 3 2 1 TIP49 AAA-lid domain AAA PF00004.29 OAG45087.1 - 2.4e-08 34.5 0.7 2.1e-05 24.9 0.0 2.9 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 OAG45087.1 - 2.8e-08 33.7 0.4 3e-05 23.8 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain DnaB_C PF03796.15 OAG45087.1 - 1.3e-06 28.0 0.9 2.4e-06 27.1 0.9 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_16 PF13191.6 OAG45087.1 - 1.8e-06 28.4 0.4 4.5e-06 27.2 0.0 2.0 2 1 0 2 2 2 1 AAA ATPase domain Mg_chelatase PF01078.21 OAG45087.1 - 0.00041 19.8 0.7 0.0042 16.5 0.4 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 OAG45087.1 - 0.0056 16.4 0.0 2.4 7.8 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_19 PF13245.6 OAG45087.1 - 0.0066 16.8 1.2 0.089 13.1 1.2 2.4 1 1 0 1 1 1 1 AAA domain Parvo_NS1 PF01057.17 OAG45087.1 - 0.013 14.6 0.1 0.021 13.9 0.1 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_5 PF07728.14 OAG45087.1 - 0.024 14.6 0.0 0.51 10.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 OAG45087.1 - 0.038 13.6 0.1 0.068 12.7 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 OAG45087.1 - 0.063 12.8 0.3 0.44 10.0 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_32 PF13654.6 OAG45087.1 - 0.063 12.0 0.2 0.14 10.9 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 OAG45087.1 - 0.085 13.1 0.0 0.18 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 OAG45087.1 - 0.13 12.5 0.0 0.36 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 OAG45087.1 - 0.14 11.9 0.9 0.67 9.7 0.9 2.0 1 1 0 1 1 1 0 AAA domain Hydin_ADK PF17213.3 OAG45087.1 - 0.21 11.9 1.7 0.25 11.6 0.2 1.9 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain TRI12 PF06609.13 OAG45088.1 - 8.8e-42 143.3 31.0 8.8e-41 140.0 31.0 1.9 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG45088.1 - 2.3e-19 69.6 54.1 6.7e-19 68.0 50.3 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG45088.1 - 1.4e-13 50.6 7.6 1.4e-13 50.6 7.6 3.1 4 0 0 4 4 4 1 Sugar (and other) transporter DUF3522 PF12036.8 OAG45088.1 - 0.026 14.8 1.2 0.026 14.8 1.2 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF3522) Fungal_trans PF04082.18 OAG45089.1 - 3.5e-14 52.5 1.5 3.5e-14 52.5 1.5 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 OAG45089.1 - 1.3e-07 31.7 14.2 0.0012 19.2 3.7 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAG45089.1 - 1.8e-06 28.3 12.6 0.00062 20.4 2.9 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OAG45089.1 - 1.1e-05 25.6 4.4 1.1e-05 25.6 4.4 4.0 4 0 0 4 4 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.8 OAG45089.1 - 0.00058 20.1 4.3 0.37 11.1 1.1 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 OAG45089.1 - 0.0016 18.3 6.3 0.087 12.7 0.3 2.6 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-C2H2_11 PF16622.5 OAG45089.1 - 0.0047 16.6 5.8 0.13 12.1 0.7 2.5 2 0 0 2 2 2 2 zinc-finger C2H2-type zf-Di19 PF05605.12 OAG45089.1 - 0.051 13.9 0.3 0.051 13.9 0.3 2.9 2 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding PyrI_C PF02748.15 OAG45089.1 - 0.73 9.8 2.4 17 5.4 0.3 2.5 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-CHCC PF10276.9 OAG45089.1 - 1.9 8.6 4.0 4.5 7.4 0.2 2.6 2 0 0 2 2 2 0 Zinc-finger domain zf-BED PF02892.15 OAG45089.1 - 4 7.5 12.0 1 9.4 5.7 2.7 1 1 1 2 2 2 0 BED zinc finger zf-C2H2_2 PF12756.7 OAG45089.1 - 6.4 7.2 7.6 3.8 7.9 1.2 2.5 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2HE PF16278.5 OAG45089.1 - 7 7.2 7.5 42 4.7 1.6 2.5 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger DUF202 PF02656.15 OAG45091.1 - 1.8e-05 25.1 3.0 1.8e-05 25.1 3.0 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF202) dCMP_cyt_deam_1 PF00383.23 OAG45092.1 - 9.7e-09 35.0 0.3 3e-08 33.5 0.3 1.8 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 OAG45092.1 - 0.0011 18.7 2.2 0.019 14.7 0.3 2.3 2 0 0 2 2 2 2 MafB19-like deaminase GYF PF02213.16 OAG45093.1 - 1e-12 47.5 2.0 2.6e-12 46.2 2.0 1.8 1 0 0 1 1 1 1 GYF domain GYF_2 PF14237.6 OAG45093.1 - 0.027 14.3 0.1 0.1 12.4 0.1 2.0 1 0 0 1 1 1 0 GYF domain 2 UFD1 PF03152.14 OAG45094.1 - 2e-70 235.8 0.0 2.5e-70 235.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CDC48_2 PF02933.17 OAG45094.1 - 0.022 14.6 0.0 0.056 13.2 0.0 1.7 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), domain 2 Fructosamin_kin PF03881.14 OAG45095.1 - 6.8e-62 209.3 0.0 2.8e-61 207.3 0.0 1.9 1 1 0 1 1 1 1 Fructosamine kinase APH PF01636.23 OAG45095.1 - 4.3e-09 36.6 0.0 8.1e-09 35.7 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 OAG45095.1 - 0.14 11.0 0.0 0.2 10.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Peptidase_M19 PF01244.21 OAG45096.1 - 8e-97 324.2 0.0 9.5e-97 324.0 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) MFS_1 PF07690.16 OAG45097.1 - 6.4e-38 130.6 22.7 6.4e-38 130.6 22.7 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF4551 PF15087.6 OAG45099.1 - 1.4 7.6 6.5 1.5 7.6 6.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) SPX PF03105.19 OAG45099.1 - 6.5 6.6 13.1 7.9 6.3 13.1 1.2 1 0 0 1 1 1 0 SPX domain Fungal_trans PF04082.18 OAG45100.1 - 1e-14 54.3 0.4 1.9e-14 53.4 0.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain COesterase PF00135.28 OAG45101.1 - 4.3e-71 240.3 0.0 7.7e-71 239.5 0.0 1.4 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAG45101.1 - 1.2e-08 35.0 0.6 9.1e-08 32.2 0.6 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OAG45101.1 - 0.065 12.7 0.4 0.11 11.9 0.4 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF1275 PF06912.11 OAG45102.1 - 1.2e-45 155.8 12.7 1.4e-45 155.6 12.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) DUF1218 PF06749.12 OAG45102.1 - 1.6 9.3 7.2 0.16 12.5 0.4 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1218) Mcl1_mid PF12341.8 OAG45103.1 - 7.7e-97 324.2 0.0 8.2e-96 320.8 0.0 2.4 2 1 0 2 2 2 1 Minichromosome loss protein, Mcl1, middle region ANAPC4_WD40 PF12894.7 OAG45103.1 - 1.8e-13 50.6 0.1 0.0039 17.4 0.0 5.2 4 1 2 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OAG45103.1 - 3.9e-12 46.5 3.8 0.0055 17.5 0.0 6.4 8 0 0 8 8 8 3 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 OAG45103.1 - 2.3e-05 23.7 0.0 8.9e-05 21.7 0.0 1.8 2 1 0 2 2 2 1 Coatomer WD associated region eIF2A PF08662.11 OAG45103.1 - 0.002 18.1 1.1 2 8.2 0.3 3.1 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A DNA_pol_alpha_N PF12254.8 OAG45103.1 - 0.032 14.3 0.8 0.08 13.0 0.8 1.6 1 0 0 1 1 1 0 DNA polymerase alpha subunit p180 N terminal Nucleoporin_N PF08801.11 OAG45103.1 - 0.042 12.6 0.4 0.11 11.2 0.0 1.8 3 0 0 3 3 3 0 Nup133 N terminal like IKI3 PF04762.12 OAG45103.1 - 0.049 11.6 0.0 0.082 10.9 0.0 1.3 1 0 0 1 1 1 0 IKI3 family BBS2_Mid PF14783.6 OAG45103.1 - 0.12 12.4 0.0 4.1 7.5 0.0 2.6 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region Abhydrolase_3 PF07859.13 OAG45104.1 - 5.1e-41 140.8 0.0 7.4e-41 140.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 OAG45104.1 - 6.4e-05 22.0 0.0 0.0002 20.4 0.0 1.7 1 1 0 1 1 1 1 Carboxylesterase family Fungal_trans PF04082.18 OAG45105.1 - 2.7e-15 56.1 1.5 5.4e-07 28.9 0.7 2.2 1 1 1 2 2 2 2 Fungal specific transcription factor domain Aminotran_4 PF01063.19 OAG45106.1 - 1.6e-20 74.0 0.0 5.8e-20 72.1 0.0 1.9 1 1 0 1 1 1 1 Amino-transferase class IV p450 PF00067.22 OAG45107.1 - 1.2e-145 485.9 0.0 2.9e-75 253.8 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 FAA_hydrolase PF01557.18 OAG45108.1 - 3.5e-60 203.4 0.0 4.5e-60 203.0 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Epimerase PF01370.21 OAG45110.1 - 0.034 13.6 0.0 0.048 13.1 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Aminotran_5 PF00266.19 OAG45111.1 - 2.2e-20 72.9 0.0 5.2e-20 71.7 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 OAG45111.1 - 1.4e-07 30.4 0.0 2.6e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 OAG45111.1 - 0.005 16.1 0.0 0.0076 15.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Nitroreductase PF00881.24 OAG45112.1 - 3.9e-10 40.0 0.0 7.1e-10 39.2 0.0 1.4 1 1 0 1 1 1 1 Nitroreductase family MFS_1 PF07690.16 OAG45113.1 - 4.4e-24 85.1 45.5 5.3e-24 84.8 38.8 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily p450 PF00067.22 OAG45114.1 - 3.9e-68 230.3 0.0 4.5e-68 230.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.18 OAG45115.1 - 4.8e-08 32.4 2.7 4.8e-08 32.4 2.7 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 OAG45115.1 - 4.9e-08 33.0 11.8 0.0012 19.2 1.8 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAG45115.1 - 0.00015 22.3 11.1 0.032 15.1 2.0 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger Zn_clus PF00172.18 OAG45115.1 - 0.033 14.3 0.5 0.064 13.4 0.5 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_jaz PF12171.8 OAG45115.1 - 0.12 12.7 8.4 0.13 12.6 0.1 3.1 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2HE PF16278.5 OAG45115.1 - 0.24 11.9 2.0 8.4 6.9 0.1 2.8 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_6 PF13912.6 OAG45115.1 - 0.3 11.1 4.8 0.86 9.7 0.7 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_11 PF16622.5 OAG45115.1 - 0.58 10.0 9.2 4.5 7.1 2.7 2.6 2 0 0 2 2 2 0 zinc-finger C2H2-type Glyoxalase PF00903.25 OAG45116.1 - 2e-06 28.0 0.0 2.6e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily TRI12 PF06609.13 OAG45117.1 - 2.8e-56 191.2 20.1 3.6e-56 190.8 20.1 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG45117.1 - 2.6e-26 92.4 52.4 1.3e-25 90.1 48.0 3.2 2 2 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG45117.1 - 4.7e-08 32.3 14.8 4.7e-08 32.3 14.8 2.9 2 1 0 2 2 2 1 Sugar (and other) transporter CDP-OH_P_transf PF01066.21 OAG45118.1 - 7.7e-13 49.0 0.8 7.7e-13 49.0 0.8 2.1 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase PP2C PF00481.21 OAG45119.1 - 1.5e-36 126.4 0.0 2.7e-29 102.6 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 OAG45119.1 - 0.009 15.7 0.1 0.087 12.5 0.0 2.2 2 0 0 2 2 2 1 Protein phosphatase 2C Retrotrans_gag PF03732.17 OAG45119.1 - 0.16 12.3 0.2 0.89 9.9 0.1 2.1 2 0 0 2 2 2 0 Retrotransposon gag protein His_Phos_1 PF00300.22 OAG45120.1 - 9.2e-15 54.8 0.5 3.7e-14 52.9 0.5 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) MFS_1 PF07690.16 OAG45121.1 - 2.1e-24 86.1 44.7 2.8e-14 52.8 24.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 OAG45121.1 - 0.00011 21.2 17.3 0.0012 17.8 0.1 3.3 2 2 1 3 3 3 3 MFS_1 like family DUF3671 PF12420.8 OAG45121.1 - 0.058 13.5 0.1 0.11 12.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF1449 PF07290.11 OAG45121.1 - 0.16 11.5 1.6 0.44 10.2 1.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1449) Cas1_AcylT PF07779.12 OAG45122.1 - 1.1e-107 360.9 14.2 1.6e-107 360.4 14.2 1.1 1 0 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p ANAPC10 PF03256.16 OAG45123.1 - 1.8e-37 128.8 0.0 8.1e-37 126.6 0.0 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) adh_short PF00106.25 OAG45124.1 - 8.7e-22 77.5 1.2 1e-21 77.3 1.2 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG45124.1 - 2.3e-21 76.4 0.8 2.7e-21 76.2 0.8 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG45124.1 - 3.5e-10 40.1 0.3 4.1e-10 39.9 0.3 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG45124.1 - 0.004 16.6 0.1 0.0044 16.5 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OAG45124.1 - 0.0068 15.4 0.1 0.0068 15.4 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family EHN PF06441.12 OAG45125.1 - 5.9e-31 107.0 0.1 5.9e-31 107.0 0.1 2.4 2 1 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 OAG45125.1 - 0.00015 21.5 0.1 0.00032 20.4 0.1 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG45125.1 - 0.043 14.4 7.0 0.56 10.8 7.0 2.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family FMO-like PF00743.19 OAG45126.1 - 3.9e-17 61.9 0.5 8e-13 47.6 0.0 3.0 2 2 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OAG45126.1 - 6.1e-12 45.4 0.0 2e-10 40.4 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAG45126.1 - 2.1e-11 43.6 0.0 1.5e-08 34.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG45126.1 - 1.6e-09 37.9 0.0 4.5e-08 33.2 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 OAG45126.1 - 6.4e-07 28.8 0.0 6e-05 22.3 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 OAG45126.1 - 4.2e-05 22.9 0.1 0.0049 16.1 0.1 2.2 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.6 OAG45126.1 - 8.9e-05 22.5 0.1 0.027 14.5 0.0 3.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 OAG45126.1 - 8.9e-05 23.0 0.3 0.066 13.8 0.3 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OAG45126.1 - 0.0024 17.0 0.1 0.5 9.4 0.1 2.9 3 0 0 3 3 3 1 Glucose inhibited division protein A HI0933_like PF03486.14 OAG45126.1 - 0.0025 16.6 0.7 0.05 12.3 0.2 2.2 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 OAG45126.1 - 0.0032 16.6 0.1 0.0086 15.2 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 OAG45126.1 - 0.0039 16.5 0.1 0.1 11.9 0.1 2.2 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 OAG45126.1 - 0.012 14.9 0.2 0.02 14.1 0.2 1.4 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.7 OAG45126.1 - 0.016 14.6 0.2 0.029 13.7 0.2 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase DAO PF01266.24 OAG45126.1 - 0.016 14.8 0.0 0.11 12.0 0.0 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase GST_N_3 PF13417.6 OAG45127.1 - 8.7e-21 74.1 0.0 1.6e-20 73.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OAG45127.1 - 1e-18 67.4 0.2 3.2e-18 65.8 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 OAG45127.1 - 4.3e-13 49.4 0.0 7.9e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAG45127.1 - 2.5e-06 27.4 0.2 5.4e-06 26.4 0.2 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 OAG45127.1 - 0.00013 22.5 0.0 0.00029 21.4 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OAG45127.1 - 0.006 16.8 0.0 0.011 16.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 OAG45127.1 - 0.12 12.6 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 Glutaredoxin NAD_binding_10 PF13460.6 OAG45128.1 - 3.2e-19 69.5 0.0 2.6e-18 66.6 0.0 2.0 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAG45128.1 - 0.018 14.5 0.0 0.028 13.9 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family FtsX_ECD PF18075.1 OAG45128.1 - 0.091 13.4 0.1 0.38 11.4 0.0 1.9 2 0 0 2 2 2 0 FtsX extracellular domain AAA_2 PF07724.14 OAG45129.1 - 4.3e-37 127.9 0.0 4.8e-36 124.4 0.0 2.3 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 OAG45129.1 - 1.9e-14 54.2 0.0 4.6e-14 53.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 OAG45129.1 - 1.5e-07 31.4 0.0 3.2e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 OAG45129.1 - 1.6e-06 28.1 0.0 3.7e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 OAG45129.1 - 0.00012 21.6 0.1 0.011 15.2 0.0 3.0 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 OAG45129.1 - 0.00093 18.9 0.0 0.089 12.5 0.0 2.3 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_22 PF13401.6 OAG45129.1 - 0.002 18.4 0.5 0.028 14.7 0.3 2.6 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OAG45129.1 - 0.004 17.5 0.9 0.013 15.9 0.1 2.3 2 1 0 2 2 1 1 AAA ATPase domain IstB_IS21 PF01695.17 OAG45129.1 - 0.0045 16.7 0.0 0.01 15.6 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_24 PF13479.6 OAG45129.1 - 0.0059 16.4 0.0 0.0092 15.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 OAG45129.1 - 0.0079 16.0 0.3 0.11 12.3 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain MCM PF00493.23 OAG45129.1 - 0.0087 15.2 0.3 0.019 14.0 0.1 1.7 2 0 0 2 2 2 1 MCM P-loop domain AAA_7 PF12775.7 OAG45129.1 - 0.042 13.4 0.0 0.079 12.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 OAG45129.1 - 0.06 13.7 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_3 PF07726.11 OAG45129.1 - 0.12 12.3 0.0 0.29 11.0 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 OAG45129.1 - 0.22 12.1 1.4 0.27 11.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 OAG45129.1 - 0.37 10.9 1.4 1.9 8.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain Hydrolase_4 PF12146.8 OAG45130.1 - 3.3e-08 33.1 0.0 0.00046 19.5 0.0 2.3 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 OAG45130.1 - 1.6e-06 27.8 0.0 0.02 14.3 0.0 2.1 1 1 1 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 OAG45130.1 - 3.1e-06 27.9 1.4 6.5e-06 26.9 1.4 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAG45130.1 - 1.3e-05 25.0 0.0 2.2e-05 24.2 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold VirJ PF06057.11 OAG45130.1 - 0.0032 17.4 0.0 0.0057 16.5 0.0 1.4 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) DUF915 PF06028.11 OAG45130.1 - 0.0034 16.8 0.0 0.007 15.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_2 PF02230.16 OAG45130.1 - 0.13 12.0 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Alpha-amylase_C PF02806.18 OAG45131.1 - 2.3e-26 92.1 0.1 5.3e-26 90.9 0.1 1.7 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.18 OAG45131.1 - 1.2e-18 67.3 0.1 3.4e-18 65.8 0.0 1.9 2 0 0 2 2 2 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 OAG45131.1 - 6.3e-15 55.6 0.2 2e-11 44.0 0.1 2.3 1 1 1 2 2 2 2 Alpha amylase, catalytic domain hDGE_amylase PF14701.6 OAG45131.1 - 0.16 11.0 0.1 0.52 9.3 0.1 1.7 2 0 0 2 2 2 0 Glycogen debranching enzyme, glucanotransferase domain MMU163 PF17119.5 OAG45132.1 - 1.4e-102 342.1 5.9 3.8e-66 222.8 1.2 2.1 1 1 1 2 2 2 2 Mitochondrial protein up-regulated during meiosis Cpn60_TCP1 PF00118.24 OAG45135.1 - 6.9e-84 282.2 13.0 1.3e-83 281.3 13.0 1.4 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family Rrf2 PF02082.20 OAG45135.1 - 0.073 13.4 0.1 0.23 11.8 0.1 1.9 1 0 0 1 1 1 0 Transcriptional regulator SGL PF08450.12 OAG45136.1 - 0.0038 16.8 0.1 0.085 12.4 0.0 2.7 3 0 0 3 3 3 1 SMP-30/Gluconolactonase/LRE-like region AA_permease_2 PF13520.6 OAG45137.1 - 1.1e-63 215.6 50.7 1.3e-63 215.3 50.7 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAG45137.1 - 8.9e-21 74.0 48.4 4.5e-20 71.7 48.4 1.8 1 1 0 1 1 1 1 Amino acid permease Cas_Csy4 PF09618.10 OAG45138.1 - 0.09 12.9 3.5 0.13 12.4 3.5 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy4) ATP-synt_ab PF00006.25 OAG45139.1 - 1.2e-61 208.1 0.2 4.6e-61 206.2 0.0 2.0 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain COX4 PF02936.14 OAG45139.1 - 4.4e-47 159.6 0.9 8.4e-47 158.7 0.9 1.5 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV ATP-synt_ab_N PF02874.23 OAG45139.1 - 4.1e-23 81.7 1.3 1.3e-22 80.0 0.7 2.2 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain RsgA_GTPase PF03193.16 OAG45139.1 - 0.016 15.1 0.1 0.039 13.8 0.1 1.6 1 0 0 1 1 1 0 RsgA GTPase NB-ARC PF00931.22 OAG45139.1 - 0.022 14.0 0.3 0.12 11.5 0.1 2.1 2 0 0 2 2 2 0 NB-ARC domain ATPase_2 PF01637.18 OAG45139.1 - 0.024 14.5 0.0 0.066 13.1 0.0 1.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 OAG45139.1 - 0.037 14.4 0.1 0.27 11.7 0.0 2.3 2 0 0 2 2 2 0 RNA helicase NACHT PF05729.12 OAG45139.1 - 0.05 13.5 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 NACHT domain T3SS_ATPase_C PF18269.1 OAG45139.1 - 0.051 13.4 0.7 0.2 11.6 0.7 2.0 1 1 0 1 1 1 0 T3SS EscN ATPase C-terminal domain ATPase PF06745.13 OAG45139.1 - 0.065 12.6 0.2 0.11 11.8 0.2 1.3 1 0 0 1 1 1 0 KaiC AAA PF00004.29 OAG45139.1 - 0.07 13.6 0.2 3.8 7.9 0.0 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF3106 PF11304.8 OAG45139.1 - 0.072 13.6 5.9 0.42 11.1 4.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3106) AAA_16 PF13191.6 OAG45139.1 - 0.087 13.2 0.1 0.45 10.9 0.1 2.2 1 1 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.6 OAG45139.1 - 0.32 11.3 3.6 0.76 10.1 0.2 2.6 3 0 0 3 3 3 0 AAA domain Cofilin_ADF PF00241.20 OAG45140.1 - 4.7e-34 116.8 0.0 5.3e-34 116.6 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein zf-met PF12874.7 OAG45142.1 - 0.0097 16.3 0.1 0.021 15.2 0.1 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 OAG45142.1 - 0.035 14.4 0.1 0.061 13.6 0.1 1.4 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Sigma70_r4 PF04545.16 OAG45142.1 - 0.36 10.4 1.7 17 5.1 0.0 3.2 3 0 0 3 3 3 0 Sigma-70, region 4 Solute_trans_a PF03619.16 OAG45146.1 - 5.2e-41 140.9 13.0 7.7e-41 140.4 13.0 1.2 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Seadorna_VP6 PF07407.11 OAG45146.1 - 0.022 13.7 0.0 0.034 13.1 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP6 protein Polysacc_synt_C PF14667.6 OAG45146.1 - 0.24 11.5 4.6 0.77 9.8 4.6 1.8 1 0 0 1 1 1 0 Polysaccharide biosynthesis C-terminal domain NUDIX PF00293.28 OAG45147.1 - 1.1e-12 48.1 0.0 2e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain INO80_Ies4 PF08193.11 OAG45147.1 - 0.022 14.8 0.0 0.034 14.1 0.0 1.2 1 0 0 1 1 1 0 INO80 complex subunit Ies4 VTC PF09359.10 OAG45148.1 - 6e-86 288.3 0.6 9.8e-86 287.6 0.6 1.4 1 0 0 1 1 1 1 VTC domain DUF202 PF02656.15 OAG45148.1 - 3.4e-11 43.4 5.8 4.1e-11 43.1 4.3 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF202) SPX PF03105.19 OAG45148.1 - 1.3e-09 38.5 13.1 6.6e-05 23.0 0.4 3.1 2 1 1 3 3 3 2 SPX domain UXS1_N PF11803.8 OAG45148.1 - 0.024 15.0 1.1 10 6.6 0.1 3.4 3 0 0 3 3 3 0 UDP-glucuronate decarboxylase N-terminal SLAC1 PF03595.17 OAG45148.1 - 0.032 13.5 0.6 0.044 13.0 0.6 1.1 1 0 0 1 1 1 0 Voltage-dependent anion channel Vps35 PF03635.17 OAG45149.1 - 0 1028.5 0.1 0 1028.3 0.1 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 Nexin_C PF08628.12 OAG45149.1 - 0.086 13.4 0.0 1.4 9.5 0.0 2.9 2 1 1 3 3 3 0 Sorting nexin C terminal Spore_coat_CotO PF14153.6 OAG45149.1 - 0.24 11.3 4.0 0.45 10.4 4.0 1.4 1 0 0 1 1 1 0 Spore coat protein CotO SAC3_GANP PF03399.16 OAG45150.1 - 0.00013 21.5 0.1 0.0011 18.5 0.0 2.2 2 1 1 3 3 3 1 SAC3/GANP family HlyIII PF03006.20 OAG45151.1 - 2.6e-32 112.4 4.7 3.3e-32 112.0 4.7 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF308 PF03729.13 OAG45151.1 - 0.028 14.7 0.2 0.028 14.7 0.2 1.8 2 0 0 2 2 2 0 Short repeat of unknown function (DUF308) TPR_19 PF14559.6 OAG45152.1 - 3e-05 24.4 0.4 0.058 13.9 0.4 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 OAG45152.1 - 0.059 13.3 0.2 0.28 11.1 0.2 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 OAG45152.1 - 0.097 13.4 1.1 5.9 7.8 0.1 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 OAG45152.1 - 0.41 11.6 2.5 1.9e+02 3.3 0.0 4.3 4 1 1 5 5 5 0 Tetratricopeptide repeat Glycos_transf_2 PF00535.26 OAG45153.1 - 1.4e-32 112.9 0.0 1.7e-32 112.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 OAG45153.1 - 9e-14 51.9 0.0 1.1e-13 51.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 OAG45153.1 - 0.00015 21.3 0.0 0.0002 21.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7N PF13733.6 OAG45153.1 - 0.01 15.5 0.0 0.019 14.6 0.0 1.4 1 0 0 1 1 1 0 N-terminal region of glycosyl transferase group 7 Glyco_transf_21 PF13506.6 OAG45153.1 - 0.067 12.7 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 21 Fungal_trans_2 PF11951.8 OAG45154.1 - 0.0013 17.6 0.9 0.002 17.0 0.9 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_transf_21 PF13506.6 OAG45155.1 - 4.2e-11 42.6 0.0 0.00057 19.4 0.0 3.5 4 0 0 4 4 4 3 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 OAG45155.1 - 0.022 14.7 0.0 0.28 11.0 0.0 2.6 3 1 0 3 3 3 0 Glycosyltransferase like family 2 WW PF00397.26 OAG45156.1 - 2.8e-09 36.9 1.5 6.5e-09 35.7 1.5 1.7 1 0 0 1 1 1 1 WW domain WRW PF10206.9 OAG45156.1 - 0.13 12.6 0.3 0.34 11.3 0.3 1.7 1 1 0 1 1 1 0 Mitochondrial F1F0-ATP synthase, subunit f HAT_KAT11 PF08214.11 OAG45157.1 - 1e-83 281.5 0.0 1.6e-83 280.9 0.0 1.2 1 0 0 1 1 1 1 Histone acetylation protein WBS28 PF15164.6 OAG45157.1 - 0.064 12.5 0.1 0.1 11.9 0.1 1.3 1 0 0 1 1 1 0 Williams-Beuren syndrome chromosomal region 28 protein homologue Asp PF00026.23 OAG45158.1 - 3.9e-08 33.1 0.0 6.1e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Sugar_tr PF00083.24 OAG45159.1 - 3.1e-62 210.9 24.2 3.9e-62 210.6 24.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG45159.1 - 9.7e-16 57.6 35.5 9.7e-16 57.6 35.5 2.3 1 1 2 3 3 3 2 Major Facilitator Superfamily DUF2070 PF09843.9 OAG45159.1 - 0.42 8.9 15.1 0.072 11.4 6.1 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) Ank_2 PF12796.7 OAG45161.1 - 4.2e-13 49.7 0.0 1.1e-11 45.1 0.0 2.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAG45161.1 - 6.2e-13 49.0 0.1 1.7e-07 31.6 0.0 4.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OAG45161.1 - 3.4e-08 33.6 0.3 4.1e-05 23.8 0.1 4.2 2 1 2 4 4 4 3 Ankyrin repeats (many copies) NACHT PF05729.12 OAG45161.1 - 4.5e-08 33.2 0.0 1.1e-07 31.9 0.0 1.8 1 0 0 1 1 1 1 NACHT domain Ank_3 PF13606.6 OAG45161.1 - 1.4e-07 31.2 0.1 0.0099 16.3 0.0 4.7 4 0 0 4 4 4 1 Ankyrin repeat Ank PF00023.30 OAG45161.1 - 0.00012 22.4 1.3 0.022 15.2 0.0 3.9 4 0 0 4 4 4 1 Ankyrin repeat AAA_22 PF13401.6 OAG45161.1 - 0.00036 20.8 0.0 0.013 15.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 OAG45161.1 - 0.00036 20.5 0.0 0.00083 19.3 0.0 1.5 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea KAP_NTPase PF07693.14 OAG45161.1 - 0.003 16.9 0.2 0.039 13.2 0.0 2.4 1 1 0 2 2 2 1 KAP family P-loop domain AAA_14 PF13173.6 OAG45161.1 - 0.014 15.5 0.1 0.53 10.3 0.1 2.9 1 1 0 1 1 1 0 AAA domain TFIIE_beta PF02186.15 OAG45161.1 - 0.063 13.6 0.2 1.3 9.3 0.1 2.9 3 0 0 3 3 2 0 TFIIE beta subunit core domain APS_kinase PF01583.20 OAG45161.1 - 0.13 12.2 0.1 0.4 10.6 0.1 1.8 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_18 PF13238.6 OAG45161.1 - 0.14 12.7 0.0 0.32 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 OAG45161.1 - 0.14 12.1 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sin3a_C PF16879.5 OAG45164.1 - 1.2e-68 231.9 1.2 1.2e-68 231.9 1.2 3.7 5 0 0 5 5 5 1 C-terminal domain of Sin3a protein PAH PF02671.21 OAG45164.1 - 5.3e-47 157.7 2.8 5.9e-18 64.7 0.0 3.9 3 1 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.12 OAG45164.1 - 2.7e-39 133.2 0.0 7.4e-39 131.8 0.0 1.8 1 0 0 1 1 1 1 Sin3 family co-repressor HSCB_C PF07743.13 OAG45166.1 - 9.1e-17 61.3 6.4 4.5e-16 59.1 5.2 2.2 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 OAG45166.1 - 1.4e-05 25.1 0.1 6.5e-05 23.0 0.0 2.1 2 0 0 2 2 2 1 DnaJ domain FDX-ACB PF03147.14 OAG45166.1 - 0.015 15.7 0.2 4.3 7.8 0.0 2.4 2 0 0 2 2 2 0 Ferredoxin-fold anticodon binding domain cwf21 PF08312.12 OAG45166.1 - 0.23 11.6 1.8 0.45 10.7 1.8 1.4 1 0 0 1 1 1 0 cwf21 domain Kinesin_assoc PF16183.5 OAG45166.1 - 1.6 8.9 4.8 0.34 11.0 1.3 1.5 2 0 0 2 2 2 0 Kinesin-associated MFS_1 PF07690.16 OAG45170.1 - 4.9e-22 78.3 32.8 4.9e-22 78.3 32.8 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 OAG45170.1 - 0.0021 16.4 1.0 0.0021 16.4 1.0 2.3 3 1 0 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family DUF4805 PF16063.5 OAG45170.1 - 0.014 14.7 1.7 0.027 13.8 1.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4805) Opi1 PF08618.10 OAG45171.1 - 1.5e-36 126.6 1.9 3.5e-26 92.4 0.2 2.4 1 1 1 2 2 2 2 Transcription factor Opi1 Sec10 PF07393.11 OAG45172.1 - 3.9e-205 683.4 0.0 4.8e-205 683.1 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 ALIX_LYPXL_bnd PF13949.6 OAG45172.1 - 0.0016 17.8 4.2 0.64 9.3 1.4 2.4 2 0 0 2 2 2 2 ALIX V-shaped domain binding to HIV DUF883 PF05957.13 OAG45172.1 - 0.55 10.9 3.6 1.4 9.6 0.1 3.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) SKIP_SNW PF02731.15 OAG45173.1 - 6.6e-72 240.4 5.7 6.6e-72 240.4 5.7 2.4 2 0 0 2 2 2 1 SKIP/SNW domain LRIF1 PF15741.5 OAG45173.1 - 0.69 8.4 10.2 1 7.8 10.2 1.1 1 0 0 1 1 1 0 Ligand-dependent nuclear receptor-interacting factor 1 Nucleo_P87 PF07267.11 OAG45173.1 - 2.2 7.1 10.9 4.4 6.0 10.9 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Methyltransf_25 PF13649.6 OAG45174.1 - 6.1e-17 62.1 0.0 2.9e-16 59.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG45174.1 - 4.4e-16 59.0 0.0 1e-15 57.9 0.0 1.5 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG45174.1 - 2.2e-14 54.0 0.0 5.5e-13 49.5 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG45174.1 - 2.8e-14 53.5 0.0 4.1e-13 49.8 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAG45174.1 - 9e-10 38.6 0.0 1.5e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 OAG45174.1 - 2.9e-05 24.1 0.0 0.0001 22.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAG45174.1 - 9.6e-05 21.8 0.0 0.0002 20.7 0.0 1.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 OAG45174.1 - 0.0011 18.8 0.0 0.004 16.9 0.0 1.8 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Pox_MCEL PF03291.16 OAG45174.1 - 0.0022 17.1 0.0 0.0037 16.4 0.0 1.3 1 0 0 1 1 1 1 mRNA capping enzyme MTS PF05175.14 OAG45174.1 - 0.0037 16.8 0.0 0.018 14.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase small domain FtsJ PF01728.19 OAG45174.1 - 0.0079 16.3 0.0 0.015 15.4 0.0 1.4 1 1 0 1 1 1 1 FtsJ-like methyltransferase FTA2 PF13095.6 OAG45175.1 - 2.9e-11 43.4 0.0 3.6e-11 43.1 0.0 1.1 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 CDC50 PF03381.15 OAG45177.1 - 5.2e-95 318.2 0.0 7e-95 317.7 0.0 1.2 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Peptidase_M43 PF05572.13 OAG45177.1 - 4.5e-09 36.4 0.2 7.8e-06 25.9 0.1 2.9 2 0 0 2 2 2 2 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 OAG45177.1 - 0.0011 19.2 9.8 0.0079 16.4 9.8 2.1 1 1 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M10 PF00413.24 OAG45177.1 - 0.1 12.5 0.0 0.19 11.6 0.0 1.4 1 1 0 1 1 1 0 Matrixin Reprolysin_2 PF13574.6 OAG45177.1 - 0.11 12.4 0.6 0.21 11.5 0.1 1.7 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like TPT PF03151.16 OAG45178.1 - 3.7e-60 203.7 12.0 4.6e-60 203.4 12.0 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 OAG45178.1 - 8e-06 26.1 32.0 0.00037 20.7 10.2 3.4 2 1 0 2 2 2 2 EamA-like transporter family PSII PF00421.19 OAG45178.1 - 0.0035 16.1 0.1 0.0062 15.3 0.1 1.3 1 0 0 1 1 1 1 Photosystem II protein UAA PF08449.11 OAG45178.1 - 0.021 14.1 14.2 0.38 9.9 14.2 2.3 1 1 0 1 1 1 0 UAA transporter family YjcB PF15940.5 OAG45178.1 - 0.32 11.2 3.3 0.53 10.5 0.3 2.4 2 0 0 2 2 2 0 Family of unknown function TMEM100 PF16311.5 OAG45178.1 - 0.37 10.4 1.8 1.2 8.7 0.0 2.2 2 0 0 2 2 2 0 Transmembrane protein 100 2TM PF13239.6 OAG45178.1 - 0.64 10.4 6.2 11 6.4 0.1 3.0 3 0 0 3 3 3 0 2TM domain Peptidase_S9 PF00326.21 OAG45179.1 - 2.9e-06 26.9 1.0 5.3e-06 26.1 1.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 OAG45179.1 - 0.00074 19.2 0.8 0.0027 17.4 0.5 2.0 2 0 0 2 2 2 1 Putative esterase Hydrolase_4 PF12146.8 OAG45179.1 - 0.021 14.1 0.1 0.073 12.3 0.0 1.9 2 1 0 2 2 2 0 Serine aminopeptidase, S33 DUF1573 PF07610.11 OAG45179.1 - 0.2 11.7 0.0 0.41 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1573) PUF PF00806.19 OAG45180.1 - 1.6e-37 125.1 3.9 1.3e-05 24.6 0.0 9.0 9 0 0 9 9 9 7 Pumilio-family RNA binding repeat RraB PF06877.11 OAG45180.1 - 0.0085 16.8 0.0 0.76 10.5 0.0 2.6 2 1 0 2 2 2 1 Regulator of ribonuclease activity B Spc7 PF08317.11 OAG45180.1 - 0.017 14.0 5.4 0.03 13.2 5.4 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein AIP3 PF03915.13 OAG45180.1 - 0.019 14.1 2.5 0.029 13.5 2.5 1.2 1 0 0 1 1 1 0 Actin interacting protein 3 RAC_head PF16717.5 OAG45180.1 - 0.025 15.5 4.2 0.11 13.5 3.8 2.2 2 0 0 2 2 2 0 Ribosome-associated complex head domain Ntox28 PF15605.6 OAG45180.1 - 0.3 11.3 1.4 0.52 10.6 0.1 2.1 2 0 0 2 2 2 0 Bacterial toxin 28 FliJ PF02050.16 OAG45180.1 - 4.5 7.5 8.8 10 6.4 8.8 1.6 1 0 0 1 1 1 0 Flagellar FliJ protein DUF5572 PF17733.1 OAG45181.1 - 4.2e-18 64.9 2.1 1e-17 63.6 2.1 1.7 1 0 0 1 1 1 1 Family of unknown function (DUF5572) WD40 PF00400.32 OAG45182.1 - 8.9e-10 39.0 12.2 0.014 16.2 0.0 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG45182.1 - 2.6e-05 24.5 0.0 7.3 7.0 0.0 4.4 4 0 0 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Myb_DNA-bind_4 PF13837.6 OAG45182.1 - 5.7e-05 23.4 0.2 0.00014 22.2 0.2 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Peptidase_C41 PF05417.11 OAG45182.1 - 0.14 12.0 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 Hepatitis E cysteine protease QRPTase_C PF01729.19 OAG45183.1 - 2.1e-54 183.8 0.1 2.6e-54 183.5 0.1 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 OAG45183.1 - 2e-19 69.4 0.0 9e-19 67.3 0.0 2.1 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain IGPS PF00218.21 OAG45183.1 - 0.016 14.4 0.2 0.031 13.4 0.1 1.4 2 0 0 2 2 2 0 Indole-3-glycerol phosphate synthase Integrase_H2C2 PF17921.1 OAG45184.1 - 0.00065 19.8 0.5 0.0019 18.3 0.1 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain Tcell_CD4_C PF12104.8 OAG45184.1 - 0.2 11.6 1.7 0.79 9.7 0.0 2.4 2 0 0 2 2 2 0 T cell CD4 receptor C terminal region ER_lumen_recept PF00810.18 OAG45186.1 - 1.3e-54 185.0 7.3 1.7e-54 184.6 7.3 1.1 1 0 0 1 1 1 1 ER lumen protein retaining receptor DUF485 PF04341.12 OAG45186.1 - 0.00097 19.0 4.9 0.0097 15.8 0.2 2.7 2 1 1 3 3 3 2 Protein of unknown function, DUF485 PQ-loop PF04193.14 OAG45186.1 - 0.14 11.9 10.9 2.4 8.0 0.1 3.6 4 0 0 4 4 4 0 PQ loop repeat DUF5122 PF17164.4 OAG45187.1 - 0.1 12.9 0.4 11 6.4 0.1 3.5 2 1 1 3 3 3 0 Domain of unknown function (DUF5122) beta-propeller Synaptobrevin PF00957.21 OAG45187.1 - 0.11 12.3 0.4 0.21 11.4 0.4 1.4 1 0 0 1 1 1 0 Synaptobrevin CPBP PF02517.16 OAG45188.1 - 1e-14 54.6 10.4 1e-14 54.6 10.4 2.5 2 1 0 2 2 2 1 CPBP intramembrane metalloprotease DUF2244 PF10003.9 OAG45188.1 - 5.3 6.7 7.3 1.5 8.5 0.5 2.9 3 0 0 3 3 3 0 Integral membrane protein (DUF2244) IBR PF01485.21 OAG45190.1 - 1.3e-20 73.4 37.4 1.6e-15 57.0 3.0 3.8 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain RWD PF05773.22 OAG45190.1 - 8.4e-18 64.7 0.0 2e-17 63.5 0.0 1.6 1 0 0 1 1 1 1 RWD domain zf-RING_5 PF14634.6 OAG45190.1 - 0.0028 17.6 11.0 0.0028 17.6 11.0 3.6 2 1 1 3 3 3 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 OAG45190.1 - 0.0044 17.0 9.9 0.0044 17.0 9.9 3.6 3 0 0 3 3 3 1 RING-type zinc-finger zf-RING_2 PF13639.6 OAG45190.1 - 0.0058 16.9 11.1 0.0058 16.9 11.1 4.4 3 1 1 4 4 4 1 Ring finger domain zf-RING_11 PF17123.5 OAG45190.1 - 0.0086 15.8 8.3 0.0086 15.8 8.3 2.4 3 0 0 3 3 3 1 RING-like zinc finger Sugar_tr PF00083.24 OAG45191.1 - 2.8e-130 435.2 30.3 3.5e-130 434.9 30.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Fungal_trans_2 PF11951.8 OAG45191.1 - 2.3e-35 122.1 0.1 3.1e-35 121.7 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 OAG45191.1 - 1.8e-21 76.5 38.2 9.9e-17 60.9 21.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily UPF0561 PF10573.9 OAG45191.1 - 0.24 11.5 1.1 0.42 10.8 0.1 1.8 2 0 0 2 2 2 0 Uncharacterised protein family UPF0561 Ring_hydroxyl_A PF00848.19 OAG45192.1 - 3.5e-07 30.4 0.0 1.8e-06 28.1 0.0 1.8 1 1 1 2 2 2 1 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.26 OAG45193.1 - 2.2e-16 59.5 0.0 4.4e-16 58.6 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Ring_hydroxyl_A PF00848.19 OAG45193.1 - 3.9e-13 49.9 0.6 9.1e-13 48.7 0.4 1.8 1 1 1 2 2 2 1 Ring hydroxylating alpha subunit (catalytic domain) Suc_Fer-like PF06999.12 OAG45194.1 - 4.2e-52 176.9 0.0 8.2e-52 175.9 0.0 1.4 1 1 0 1 1 1 1 Sucrase/ferredoxin-like DUF3723 PF12520.8 OAG45194.1 - 0.18 10.4 0.0 0.26 9.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3723) Metallophos PF00149.28 OAG45195.1 - 1.5e-10 41.9 0.8 2.3e-10 41.3 0.8 1.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase RPA43_OB PF17875.1 OAG45197.1 - 1.2 9.7 8.9 8.2 7.1 0.5 2.5 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I XhlA PF10779.9 OAG45197.1 - 9.3 6.5 7.1 2.1 8.6 1.8 2.5 2 0 0 2 2 2 0 Haemolysin XhlA Metallophos PF00149.28 OAG45198.1 - 8.4e-11 42.8 0.0 1.3e-10 42.1 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OAG45198.1 - 1.9e-06 28.1 0.6 8.1e-06 26.1 0.1 2.0 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain FBPase_2 PF06874.11 OAG45198.1 - 0.023 13.0 0.1 0.27 9.5 0.1 2.0 1 1 1 2 2 2 0 Firmicute fructose-1,6-bisphosphatase ResIII PF04851.15 OAG45200.1 - 2.1e-21 76.7 0.0 5.3e-21 75.4 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 OAG45200.1 - 1.1e-20 74.0 0.1 3e-20 72.6 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 OAG45200.1 - 8.5e-18 64.7 0.0 2.2e-17 63.4 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase HUN PF08729.10 OAG45200.1 - 0.0054 16.7 3.1 0.0054 16.7 3.1 2.6 3 0 0 3 3 3 1 HPC2 and ubinuclein domain AAA_22 PF13401.6 OAG45200.1 - 0.17 12.2 0.0 0.79 10.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain ADH_zinc_N PF00107.26 OAG45201.1 - 1.1e-14 54.6 0.0 2.3e-14 53.5 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAG45201.1 - 8.6e-12 46.3 0.0 2e-11 45.0 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAG45201.1 - 3.6e-09 36.5 0.0 2.4e-08 33.8 0.0 2.1 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain DUF3573 PF12097.8 OAG45202.1 - 0.039 12.8 0.2 0.34 9.7 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3573) AAT PF03417.16 OAG45203.1 - 1.4e-27 96.8 0.0 1.9e-27 96.4 0.0 1.1 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Amidohydro_1 PF01979.20 OAG45204.1 - 4.8e-19 68.9 0.0 1.1e-18 67.7 0.0 1.5 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 OAG45204.1 - 1.4e-10 41.2 2.7 6.6e-07 29.1 0.0 2.9 2 1 0 2 2 2 2 Amidohydrolase family PGA_cap PF09587.10 OAG45205.1 - 2.1e-66 224.0 0.0 2.7e-66 223.7 0.0 1.1 1 0 0 1 1 1 1 Bacterial capsule synthesis protein PGA_cap MFS_1 PF07690.16 OAG45206.1 - 6.3e-36 124.0 37.3 6.3e-36 124.0 37.3 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 OAG45206.1 - 0.0006 19.2 7.5 0.0006 19.2 7.5 2.2 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB COesterase PF00135.28 OAG45207.1 - 4.9e-93 312.7 0.0 6.8e-93 312.3 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAG45207.1 - 4.2e-07 30.1 0.1 2.3e-06 27.6 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Oxidored_FMN PF00724.20 OAG45208.1 - 8.2e-89 298.2 0.0 9.4e-89 298.0 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Abhydrolase_1 PF00561.20 OAG45209.1 - 3.6e-20 72.7 0.3 1.6e-19 70.6 0.3 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG45209.1 - 3.2e-14 54.1 1.1 1.3e-13 52.1 1.1 2.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG45209.1 - 1.9e-11 43.7 0.0 1.5e-06 27.6 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 OAG45209.1 - 3.8e-05 23.7 0.0 0.00013 22.0 0.0 1.9 2 0 0 2 2 2 1 TAP-like protein Fungal_trans PF04082.18 OAG45209.1 - 0.00015 20.9 0.9 0.00025 20.2 0.4 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Peptidase_S9 PF00326.21 OAG45209.1 - 0.0048 16.4 0.0 2.4 7.6 0.0 2.4 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_5 PF12695.7 OAG45209.1 - 0.0064 16.3 0.0 0.019 14.7 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Thioesterase PF00975.20 OAG45209.1 - 0.015 15.4 0.0 0.051 13.7 0.0 1.9 1 0 0 1 1 1 0 Thioesterase domain Ser_hydrolase PF06821.13 OAG45209.1 - 0.028 14.3 0.0 8.8 6.2 0.0 2.8 3 0 0 3 3 3 0 Serine hydrolase Zn_clus PF00172.18 OAG45209.1 - 0.065 13.4 0.4 0.12 12.6 0.4 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DLH PF01738.18 OAG45209.1 - 0.077 12.5 0.0 1.1 8.8 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family Esterase PF00756.20 OAG45209.1 - 0.088 12.4 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 Putative esterase Beta-lactamase PF00144.24 OAG45210.1 - 1.9e-60 204.9 0.1 2.2e-60 204.6 0.1 1.1 1 0 0 1 1 1 1 Beta-lactamase Inhibitor_I36 PF03995.13 OAG45210.1 - 0.06 13.3 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Peptidase inhibitor family I36 Aldo_ket_red PF00248.21 OAG45211.1 - 9.6e-61 205.5 0.0 1.2e-60 205.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family adh_short_C2 PF13561.6 OAG45212.1 - 2.8e-31 108.9 0.0 1.1e-28 100.4 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG45212.1 - 2.2e-14 53.4 0.0 2.5e-11 43.4 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short PF00106.25 OAG45213.1 - 2.8e-35 121.6 0.1 3.8e-35 121.1 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG45213.1 - 3.1e-28 98.9 0.0 3.9e-28 98.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG45213.1 - 0.019 14.9 0.4 0.36 10.7 0.4 2.6 1 1 0 1 1 1 0 KR domain CbiA PF01656.23 OAG45213.1 - 0.17 12.0 0.0 0.28 11.2 0.0 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF5400 PF17379.2 OAG45214.1 - 0.28 11.6 3.3 0.47 11.0 3.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5400) ACBP PF00887.19 OAG45216.1 - 3e-22 78.6 0.0 1.2e-21 76.7 0.0 2.0 2 0 0 2 2 2 1 Acyl CoA binding protein FERM_M PF00373.18 OAG45216.1 - 0.022 15.2 0.0 0.051 14.0 0.0 1.6 1 0 0 1 1 1 0 FERM central domain DUF2046 PF09755.9 OAG45216.1 - 0.042 13.1 0.1 0.085 12.1 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein H4 (DUF2046) DUF2237 PF09996.9 OAG45217.1 - 2.7e-39 133.7 0.1 3.6e-39 133.3 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2237) MFS_1 PF07690.16 OAG45218.1 - 2e-35 122.4 33.7 2e-35 122.4 33.7 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 OAG45218.1 - 5.1e-09 35.1 8.0 7.9e-09 34.5 8.0 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) LapA_dom PF06305.11 OAG45218.1 - 0.8 9.6 0.0 0.8 9.6 0.0 3.2 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain PAP2_C PF14360.6 OAG45218.1 - 1.5 9.4 8.0 0.33 11.5 2.5 2.8 2 0 0 2 2 2 0 PAP2 superfamily C-terminal PQ-loop PF04193.14 OAG45220.1 - 9.1e-26 89.4 0.8 5.9e-16 58.0 0.1 2.6 2 0 0 2 2 2 2 PQ loop repeat ER_lumen_recept PF00810.18 OAG45220.1 - 0.003 18.4 0.5 0.0066 17.3 0.5 1.6 1 1 0 1 1 1 1 ER lumen protein retaining receptor Mid2 PF04478.12 OAG45221.1 - 3.1e-05 23.8 0.0 5.8e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor SKG6 PF08693.10 OAG45221.1 - 0.0017 17.8 0.1 0.0017 17.8 0.1 2.0 2 0 0 2 2 2 1 Transmembrane alpha-helix domain TMEM154 PF15102.6 OAG45221.1 - 0.0029 17.5 0.0 0.0063 16.4 0.0 1.6 1 0 0 1 1 1 1 TMEM154 protein family DUF4448 PF14610.6 OAG45221.1 - 0.019 14.8 0.0 0.049 13.4 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4448) DUF347 PF03988.12 OAG45221.1 - 0.036 14.3 2.6 0.043 14.0 0.0 2.3 3 0 0 3 3 3 0 Repeat of Unknown Function (DUF347) Adeno_E3_CR2 PF02439.15 OAG45221.1 - 0.051 13.3 0.2 0.088 12.6 0.2 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 CcmD PF04995.14 OAG45221.1 - 0.13 12.4 0.4 0.13 12.4 0.4 1.8 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) MGC-24 PF05283.11 OAG45221.1 - 1 9.8 5.6 2.8 8.4 5.6 1.7 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Glyco_hydro_31 PF01055.26 OAG45222.1 - 6.3e-139 464.0 4.4 8.8e-139 463.5 4.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 OAG45222.1 - 1.3e-27 95.8 1.5 3.8e-26 91.2 0.5 2.6 2 0 0 2 2 2 1 Galactose mutarotase-like DUF5110 PF17137.4 OAG45222.1 - 3.7e-07 30.3 0.2 1.5e-06 28.4 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF5110) NDK PF00334.19 OAG45223.1 - 9e-54 181.1 0.0 1e-53 181.0 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase FLILHELTA PF10306.9 OAG45224.1 - 8.6e-29 99.8 0.8 1.4e-28 99.1 0.3 1.6 2 0 0 2 2 2 1 Hypothetical protein FLILHELTA DUF1279 PF06916.13 OAG45224.1 - 0.082 13.5 0.4 0.11 13.1 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1279) F-box_4 PF15966.5 OAG45225.1 - 0.032 14.1 0.1 0.08 12.8 0.1 1.7 1 0 0 1 1 1 0 F-box Kelch_5 PF13854.6 OAG45226.1 - 6.5e-16 57.9 8.2 1.9e-10 40.5 0.2 4.6 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.6 OAG45226.1 - 2.8e-06 27.4 5.2 0.014 15.7 0.1 5.1 6 0 0 6 6 6 2 Kelch motif SKG6 PF08693.10 OAG45226.1 - 6e-06 25.6 1.0 1.3e-05 24.4 1.0 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Kelch_4 PF13418.6 OAG45226.1 - 0.0017 18.3 3.9 0.043 13.8 0.1 3.8 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_2 PF07646.15 OAG45226.1 - 0.0022 17.9 13.0 0.11 12.5 0.1 5.9 5 1 0 5 5 5 1 Kelch motif Amnionless PF14828.6 OAG45226.1 - 0.042 12.7 0.0 0.059 12.2 0.0 1.1 1 0 0 1 1 1 0 Amnionless Phage_HK97_TLTM PF06120.11 OAG45226.1 - 0.22 10.7 0.0 0.32 10.1 0.0 1.1 1 0 0 1 1 1 0 Tail length tape measure protein Kelch_1 PF01344.25 OAG45226.1 - 0.33 10.6 21.5 0.15 11.6 0.4 6.4 8 1 0 8 8 8 0 Kelch motif AF-4 PF05110.13 OAG45226.1 - 4 5.4 5.7 5.3 5.0 5.7 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein bZIP_1 PF00170.21 OAG45227.1 - 0.00094 19.2 7.1 0.0015 18.6 7.1 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 OAG45227.1 - 1.4 9.5 10.6 2.8 8.5 10.6 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor Fungal_trans PF04082.18 OAG45228.1 - 2.7e-20 72.5 5.3 2.8e-20 72.5 1.3 2.4 2 1 0 2 2 2 1 Fungal specific transcription factor domain GST_N_3 PF13417.6 OAG45230.1 - 1.5e-09 38.1 0.0 2.5e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OAG45230.1 - 1.6e-09 37.9 0.0 3.3e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 OAG45230.1 - 1.3e-07 31.8 0.0 2.2e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OAG45230.1 - 1.2e-06 28.7 0.0 2.1e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OAG45230.1 - 1.4e-06 28.5 0.0 3e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OAG45230.1 - 0.0026 17.8 0.1 0.0039 17.2 0.1 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain T3SS_needle_reg PF09025.10 OAG45231.1 - 0.013 15.5 0.0 0.02 14.8 0.0 1.3 1 0 0 1 1 1 0 YopR, type III needle-polymerisation regulator DMRT-like PF15791.5 OAG45232.1 - 0.068 13.6 0.1 0.068 13.6 0.1 2.9 3 0 0 3 3 3 0 Doublesex-and mab-3-related transcription factor C1 and C2 Epimerase PF01370.21 OAG45233.1 - 3.9e-08 33.0 0.0 2.4e-07 30.5 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 OAG45233.1 - 0.065 12.8 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family Polysacc_synt_2 PF02719.15 OAG45233.1 - 0.085 12.0 0.0 0.23 10.6 0.0 1.7 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 OAG45233.1 - 0.11 11.6 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein Thioredox_DsbH PF03190.15 OAG45234.1 - 2.1e-65 219.6 0.0 3.4e-65 218.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.6 OAG45234.1 - 2.4e-07 30.8 0.0 4.9e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like Sigma70_r4 PF04545.16 OAG45234.1 - 0.057 13.0 0.1 0.12 12.0 0.1 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 Glyco_hydro_9 PF00759.19 OAG45234.1 - 0.087 12.2 1.6 0.15 11.5 1.6 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 9 WD40 PF00400.32 OAG45235.1 - 1.8e-14 53.9 12.4 0.0014 19.4 0.1 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.8 OAG45235.1 - 0.03 13.0 1.1 1 7.9 0.3 2.8 2 1 1 3 3 3 0 Nucleoporin Nup120/160 LSM14 PF12701.7 OAG45236.1 - 5.8e-27 93.6 0.1 9.2e-27 93.0 0.1 1.3 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.10 OAG45236.1 - 3e-19 69.8 7.1 3e-19 69.8 7.1 1.9 2 0 0 2 2 2 1 FDF domain SM-ATX PF14438.6 OAG45236.1 - 0.0021 18.1 0.0 0.0043 17.2 0.0 1.5 1 0 0 1 1 1 1 Ataxin 2 SM domain TFIIA PF03153.13 OAG45236.1 - 4.3 7.2 13.7 6.4 6.7 13.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Transp_cyt_pur PF02133.15 OAG45238.1 - 6.8e-92 308.5 38.1 7.9e-92 308.3 38.1 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DIOX_N PF14226.6 OAG45239.1 - 2.3e-30 105.7 0.0 3.7e-30 105.1 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OAG45239.1 - 1.8e-18 66.9 0.0 3.1e-18 66.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Ppx-GppA PF02541.16 OAG45240.1 - 4.7e-43 147.7 0.0 1.3e-42 146.2 0.0 1.7 1 1 0 1 1 1 1 Ppx/GppA phosphatase family DIOX_N PF14226.6 OAG45241.1 - 1.1e-16 61.6 0.1 3.4e-16 60.1 0.0 1.8 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OAG45241.1 - 1.3e-11 44.9 0.0 3.3e-11 43.6 0.0 1.7 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Sugar_tr PF00083.24 OAG45242.1 - 2.9e-85 286.8 19.2 3.4e-85 286.6 19.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG45242.1 - 4.3e-21 75.2 29.2 4.4e-18 65.3 18.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ABM PF03992.16 OAG45243.1 - 1.9e-11 43.9 0.1 2.3e-11 43.6 0.1 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Arylesterase PF01731.20 OAG45244.1 - 1.5e-06 28.3 0.0 3.7e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 Arylesterase SGL PF08450.12 OAG45244.1 - 0.00018 21.2 0.0 0.00031 20.4 0.0 1.3 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 OAG45244.1 - 0.054 13.6 0.0 0.14 12.3 0.0 1.7 1 0 0 1 1 1 0 Strictosidine synthase adh_short_C2 PF13561.6 OAG45245.1 - 1.9e-60 204.4 0.1 2.5e-60 204.0 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG45245.1 - 5.6e-48 163.0 0.4 7.2e-48 162.6 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG45245.1 - 3.1e-07 30.5 0.6 7.5e-07 29.2 0.6 1.7 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OAG45245.1 - 0.0024 17.1 0.0 0.0037 16.4 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Methyltransf_25 PF13649.6 OAG45245.1 - 0.14 12.9 0.0 0.31 11.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain K_oxygenase PF13434.6 OAG45246.1 - 7.1e-17 61.6 0.2 6.4e-13 48.5 0.1 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 OAG45246.1 - 2.1e-16 60.0 0.0 1.1e-13 51.2 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 OAG45246.1 - 2.9e-13 49.1 0.6 9.9e-12 44.0 0.0 2.2 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OAG45246.1 - 4e-13 49.3 0.1 1.9e-10 40.5 0.0 2.9 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG45246.1 - 2.5e-11 43.6 0.1 3.7e-08 33.5 0.0 3.4 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAG45246.1 - 7.9e-09 35.5 0.5 1.5e-05 24.7 0.0 3.4 2 1 1 3 3 3 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 OAG45246.1 - 5.5e-07 29.7 0.3 0.0057 16.6 0.0 4.2 3 1 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 OAG45246.1 - 7.5e-07 29.6 0.3 0.0062 17.1 0.0 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAG45246.1 - 0.00011 21.5 0.2 0.0054 16.0 0.0 2.6 3 0 0 3 3 3 1 Thi4 family HI0933_like PF03486.14 OAG45246.1 - 0.001 17.8 0.1 0.056 12.1 0.0 2.5 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_7 PF13241.6 OAG45246.1 - 0.0011 19.4 0.0 0.6 10.6 0.0 2.8 3 1 1 4 4 2 1 Putative NAD(P)-binding Lycopene_cycl PF05834.12 OAG45246.1 - 0.0017 17.5 0.2 0.05 12.6 0.1 2.7 2 1 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 OAG45246.1 - 0.0018 17.4 0.9 0.0041 16.2 0.0 2.0 3 0 0 3 3 3 1 FAD binding domain Shikimate_DH PF01488.20 OAG45246.1 - 0.0029 17.7 0.0 0.27 11.3 0.0 2.6 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 OAG45246.1 - 0.025 14.0 0.0 0.045 13.1 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 OAG45246.1 - 0.049 13.8 0.1 0.56 10.4 0.0 2.2 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Amino_oxidase PF01593.24 OAG45246.1 - 0.081 12.2 0.0 15 4.7 0.0 3.1 4 0 0 4 4 4 0 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.21 OAG45246.1 - 0.12 11.6 0.3 11 5.2 0.0 2.8 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 OAG45246.1 - 0.15 11.1 1.2 15 4.5 0.0 2.8 4 0 0 4 4 4 0 Glucose inhibited division protein A 4HBT PF03061.22 OAG45247.1 - 4.8e-09 36.5 0.0 7.3e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_2 PF13279.6 OAG45247.1 - 0.00021 21.8 0.0 0.00027 21.4 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.17 OAG45247.1 - 0.00068 19.0 0.2 0.00096 18.5 0.2 1.2 1 0 0 1 1 1 1 Acyl-ACP thioesterase AMP-binding PF00501.28 OAG45248.1 - 6.7e-43 146.8 0.0 9.3e-43 146.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 OAG45248.1 - 1.5e-06 28.0 1.3 2.8e-06 27.1 0.1 2.1 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 OAG45248.1 - 0.0087 17.0 0.0 0.032 15.2 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ECH_1 PF00378.20 OAG45249.1 - 1.5e-54 185.0 0.0 2.2e-54 184.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAG45249.1 - 5.5e-29 101.7 0.0 4.4e-25 88.9 0.0 2.1 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase DUF884 PF05959.11 OAG45249.1 - 0.15 11.6 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF884) adh_short PF00106.25 OAG45250.1 - 3.3e-38 131.1 0.0 5.7e-38 130.3 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG45250.1 - 1.5e-35 122.9 0.0 2e-35 122.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG45250.1 - 0.032 14.2 0.2 0.14 12.0 0.2 1.9 1 1 0 1 1 1 0 KR domain Fungal_trans PF04082.18 OAG45251.1 - 4.8e-13 48.8 1.0 8e-13 48.0 1.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 OAG45251.1 - 6.6e-09 35.7 7.2 0.00016 21.9 1.5 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAG45251.1 - 0.00016 22.3 6.9 0.26 12.3 0.4 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger DZR PF12773.7 OAG45251.1 - 0.039 14.0 0.5 0.11 12.6 0.5 1.7 1 0 0 1 1 1 0 Double zinc ribbon zf-C2H2_11 PF16622.5 OAG45251.1 - 0.2 11.5 9.2 0.63 9.9 1.1 2.6 2 0 0 2 2 2 0 zinc-finger C2H2-type Trypsin_2 PF13365.6 OAG45252.1 - 4.9e-08 34.0 0.2 2.4e-06 28.5 0.2 2.3 1 1 0 1 1 1 1 Trypsin-like peptidase domain Prok-RING_2 PF14445.6 OAG45252.1 - 0.096 12.9 0.2 0.22 11.7 0.2 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 2 Glyco_hyd_65N_2 PF14498.6 OAG45253.1 - 2.7e-53 181.3 0.0 3.8e-53 180.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain SUA5 PF03481.13 OAG45253.1 - 0.093 13.3 0.0 0.76 10.3 0.0 2.1 1 1 0 1 1 1 0 Putative GTP-binding controlling metal-binding ECH_1 PF00378.20 OAG45255.1 - 9.8e-29 100.4 0.1 1.3e-28 100.0 0.1 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAG45255.1 - 5.7e-18 65.5 0.1 6.6e-18 65.3 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Aldedh PF00171.22 OAG45256.1 - 6.3e-149 496.4 0.0 7.4e-149 496.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family AMP-binding PF00501.28 OAG45257.1 - 3.7e-42 144.4 0.0 4.8e-42 144.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG45257.1 - 7.2e-14 52.5 0.1 1.3e-13 51.8 0.1 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ECH_1 PF00378.20 OAG45258.1 - 9.5e-32 110.3 0.0 1.1e-31 110.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAG45258.1 - 2.4e-12 47.0 0.0 2.9e-12 46.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Defb50 PF17546.2 OAG45258.1 - 0.074 13.0 0.1 0.14 12.1 0.1 1.4 1 0 0 1 1 1 0 Beta defensin 50 ACOX PF01756.19 OAG45259.1 - 4.1e-40 137.3 1.4 3.4e-39 134.3 0.5 2.8 4 0 0 4 4 4 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 OAG45259.1 - 6.8e-25 88.0 0.3 2.3e-24 86.3 0.1 2.1 2 0 0 2 2 2 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 OAG45259.1 - 5.4e-11 42.6 0.0 1.1e-10 41.5 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 OAG45259.1 - 0.0099 16.1 1.6 0.082 13.1 1.6 2.3 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Fungal_trans PF04082.18 OAG45259.1 - 0.054 12.5 0.0 0.12 11.4 0.0 1.6 1 0 0 1 1 1 0 Fungal specific transcription factor domain ADH_N PF08240.12 OAG45260.1 - 1e-28 99.4 0.3 2e-28 98.4 0.3 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG45260.1 - 1e-14 54.6 0.4 1.8e-14 53.8 0.4 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 OAG45260.1 - 2.3e-06 27.3 0.2 5.4e-06 26.0 0.2 1.6 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 OAG45260.1 - 2.6e-06 26.9 0.8 5e-06 26.0 0.8 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.6 OAG45260.1 - 1.5e-05 26.1 0.1 4.4e-05 24.5 0.1 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 OAG45260.1 - 0.00039 20.3 0.0 0.00086 19.2 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated TrkA_N PF02254.18 OAG45260.1 - 0.027 14.7 0.4 0.045 14.0 0.4 1.3 1 0 0 1 1 1 0 TrkA-N domain FMO-like PF00743.19 OAG45261.1 - 1.9e-20 72.8 1.3 1.4e-19 69.9 0.4 2.3 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 OAG45261.1 - 5.7e-09 35.6 0.6 5.3e-06 25.8 0.0 3.4 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 OAG45261.1 - 1.2e-08 35.0 0.0 3.3e-08 33.6 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAG45261.1 - 4.9e-06 26.0 0.0 4.6e-05 22.8 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAG45261.1 - 2.3e-05 23.8 0.2 0.00036 19.9 0.0 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAG45261.1 - 0.0043 17.1 0.0 0.039 13.9 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Shikimate_DH PF01488.20 OAG45261.1 - 0.056 13.5 0.1 6.7 6.8 0.0 3.4 4 0 0 4 4 4 0 Shikimate / quinate 5-dehydrogenase DAO PF01266.24 OAG45261.1 - 0.064 12.8 0.0 7.2 6.1 0.0 2.6 3 0 0 3 3 3 0 FAD dependent oxidoreductase Phosducin PF02114.16 OAG45261.1 - 0.13 11.1 0.0 0.23 10.4 0.0 1.3 1 0 0 1 1 1 0 Phosducin Thi4 PF01946.17 OAG45261.1 - 0.25 10.6 0.3 0.98 8.6 0.0 2.1 3 0 0 3 3 3 0 Thi4 family MFS_1 PF07690.16 OAG45262.1 - 1.5e-33 116.2 24.5 1.5e-33 116.2 24.5 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Aldo_ket_red PF00248.21 OAG45266.1 - 5e-22 78.5 0.1 2.4e-21 76.2 0.0 1.8 1 1 1 2 2 2 1 Aldo/keto reductase family Dynamin_N PF00350.23 OAG45268.1 - 4.4e-27 95.2 0.0 7.2e-27 94.5 0.0 1.4 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 OAG45268.1 - 8.7e-18 64.5 0.0 1.7e-17 63.6 0.0 1.4 1 0 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.23 OAG45268.1 - 0.00013 22.0 0.0 0.00062 19.8 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase GED PF02212.18 OAG45268.1 - 0.00057 20.0 0.1 0.0014 18.7 0.1 1.6 1 0 0 1 1 1 1 Dynamin GTPase effector domain Fungal_trans_2 PF11951.8 OAG45269.1 - 2.6e-15 56.1 0.0 6.7e-14 51.5 0.0 2.2 1 1 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 OAG45270.1 - 8.3e-09 34.8 60.3 1.4e-06 27.5 23.9 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily E1-E2_ATPase PF00122.20 OAG45271.1 - 2.4e-44 151.0 2.1 2.4e-44 151.0 2.1 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 OAG45271.1 - 2.8e-21 76.8 0.6 4.9e-21 76.0 0.6 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase APH PF01636.23 OAG45271.1 - 3.6e-14 53.3 0.0 2.6e-13 50.5 0.0 2.4 2 1 0 2 2 2 1 Phosphotransferase enzyme family HMA PF00403.26 OAG45271.1 - 0.00022 21.6 0.0 0.00057 20.3 0.0 1.8 1 0 0 1 1 1 1 Heavy-metal-associated domain Nucleoporin_C PF03177.14 OAG45271.1 - 0.0084 14.9 0.1 0.013 14.2 0.1 1.2 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal DUF1351 PF07083.11 OAG45271.1 - 0.013 15.3 0.0 0.024 14.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1351) ACT_6 PF13740.6 OAG45271.1 - 0.051 13.6 0.0 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 ACT domain Aldo_ket_red PF00248.21 OAG45273.1 - 4.7e-70 236.1 0.0 5.3e-70 235.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family F_actin_cap_B PF01115.17 OAG45274.1 - 1.2e-99 332.8 0.0 1.4e-99 332.6 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit Zn_clus PF00172.18 OAG45275.1 - 8.6e-10 38.6 8.4 8.6e-10 38.6 8.4 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAG45275.1 - 5.1e-08 32.3 1.4 9.6e-08 31.4 1.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain TPR_16 PF13432.6 OAG45276.1 - 0.019 15.6 0.0 0.055 14.1 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat Fungal_trans_2 PF11951.8 OAG45276.1 - 0.081 11.7 0.1 0.12 11.2 0.1 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain DUF1772 PF08592.11 OAG45277.1 - 0.0054 17.0 5.1 0.016 15.5 5.1 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) Fungal_trans PF04082.18 OAG45278.1 - 1.4e-29 103.0 1.3 2.3e-29 102.3 1.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Beta-lactamase PF00144.24 OAG45279.1 - 1.1e-38 133.3 0.3 3.4e-38 131.7 0.3 1.8 1 1 0 1 1 1 1 Beta-lactamase AMP-binding PF00501.28 OAG45280.1 - 8.6e-78 261.8 0.0 1.1e-77 261.5 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG45280.1 - 6.4e-12 46.3 0.0 1.6e-11 45.0 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain NAD_binding_8 PF13450.6 OAG45281.1 - 2.3e-07 30.9 0.0 2.6e-05 24.4 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 OAG45281.1 - 3.9e-07 29.5 0.0 0.00025 20.3 0.0 2.8 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 OAG45281.1 - 1.6e-05 24.3 0.0 8.4e-05 21.9 0.0 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 OAG45281.1 - 2.5e-05 22.9 0.0 6.9e-05 21.5 0.0 1.6 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Shikimate_DH PF01488.20 OAG45281.1 - 0.0009 19.3 0.1 0.0071 16.4 0.1 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 OAG45281.1 - 0.0028 17.0 0.0 0.0061 15.9 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 OAG45281.1 - 0.0094 16.4 0.0 0.16 12.5 0.0 2.4 2 0 0 2 2 2 1 Putative NAD(P)-binding 40S_S4_C PF16121.5 OAG45281.1 - 0.088 12.5 0.0 0.23 11.2 0.0 1.7 1 0 0 1 1 1 0 40S ribosomal protein S4 C-terminus Pyr_redox PF00070.27 OAG45281.1 - 0.14 12.7 2.3 1.2 9.8 0.0 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase MARVEL PF01284.23 OAG45283.1 - 4.3 7.4 15.3 1.4 9.0 6.9 2.4 1 1 0 2 2 2 0 Membrane-associating domain Peptidase_C48 PF02902.19 OAG45284.1 - 1.6e-15 57.6 0.0 2.5e-15 56.9 0.0 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Leu_Phe_trans PF03588.14 OAG45284.1 - 0.11 12.0 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Leucyl/phenylalanyl-tRNA protein transferase Peptidase_C14 PF00656.22 OAG45285.1 - 1.1e-18 68.1 0.0 1.9e-18 67.3 0.0 1.4 1 0 0 1 1 1 1 Caspase domain CHAT PF12770.7 OAG45286.1 - 3.1e-32 112.1 0.0 7.1e-32 111.0 0.0 1.6 2 0 0 2 2 2 1 CHAT domain DUF2225 PF09986.9 OAG45286.1 - 0.027 14.2 0.3 0.076 12.7 0.3 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) CEP209_CC5 PF16574.5 OAG45286.1 - 0.031 14.5 1.0 0.12 12.5 0.2 2.3 2 0 0 2 2 2 0 Coiled-coil region of centrosome protein CE290 adh_short PF00106.25 OAG45287.1 - 2.2e-31 108.8 0.0 4e-14 52.5 0.0 3.0 1 1 2 3 3 3 3 short chain dehydrogenase adh_short_C2 PF13561.6 OAG45287.1 - 7.5e-25 87.8 0.1 1.1e-13 51.2 0.0 3.0 1 1 2 3 3 3 3 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG45287.1 - 1.1e-05 25.4 0.0 1.6e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 KR domain SurE PF01975.17 OAG45287.1 - 0.11 12.2 0.1 0.21 11.3 0.0 1.5 2 0 0 2 2 2 0 Survival protein SurE Beta-lactamase PF00144.24 OAG45289.1 - 1.8e-44 152.4 0.0 8.6e-44 150.1 0.0 1.8 1 1 0 1 1 1 1 Beta-lactamase SbcCD_C PF13558.6 OAG45290.1 - 0.11 12.8 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Syntaxin-6_N PF09177.11 OAG45290.1 - 0.22 12.1 1.4 0.72 10.4 0.2 2.4 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Sugar_tr PF00083.24 OAG45291.1 - 2.9e-85 286.8 21.9 3.2e-85 286.7 21.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG45291.1 - 3.9e-26 91.8 49.0 1.4e-18 67.0 33.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.18 OAG45292.1 - 2e-14 53.3 0.5 3e-14 52.7 0.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain AA_permease PF00324.21 OAG45293.1 - 5.2e-64 216.6 30.9 5.4e-62 209.9 25.5 2.0 2 0 0 2 2 2 2 Amino acid permease AA_permease_2 PF13520.6 OAG45293.1 - 6.9e-24 84.5 29.5 6.9e-24 84.5 29.5 1.7 2 0 0 2 2 2 1 Amino acid permease adh_short_C2 PF13561.6 OAG45295.1 - 6.9e-38 130.5 1.3 1e-36 126.7 1.3 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAG45295.1 - 1.4e-28 99.6 0.4 2.9e-28 98.7 0.4 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAG45295.1 - 3.9e-05 23.6 0.4 0.00012 22.0 0.2 1.7 1 1 1 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 OAG45295.1 - 0.16 11.0 0.0 0.23 10.6 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF3402 PF11882.8 OAG45296.1 - 7e-172 572.7 0.0 8.9e-172 572.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.13 OAG45296.1 - 4.6e-78 262.3 0.1 4.6e-78 262.3 0.1 1.4 2 0 0 2 2 2 1 N1221-like protein Med11 PF10280.9 OAG45297.1 - 5.6e-31 107.8 0.1 7e-31 107.5 0.1 1.1 1 0 0 1 1 1 1 Mediator complex protein WD40 PF00400.32 OAG45298.1 - 6.2e-42 140.8 26.9 2.3e-07 31.4 0.9 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 OAG45298.1 - 1.2e-34 119.4 0.6 1.8e-34 118.8 0.6 1.3 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.7 OAG45298.1 - 2.6e-09 37.2 0.7 0.042 14.1 0.0 5.1 2 1 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OAG45298.1 - 4.5e-05 22.3 0.1 0.025 13.2 0.1 2.4 2 0 0 2 2 2 2 Nucleoporin Nup120/160 eIF2A PF08662.11 OAG45298.1 - 0.013 15.3 0.1 0.03 14.2 0.1 1.5 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A Rhomboid PF01694.22 OAG45299.1 - 8.5e-21 74.5 3.7 1e-20 74.3 3.7 1.1 1 0 0 1 1 1 1 Rhomboid family HDA2-3 PF11496.8 OAG45300.1 - 6.1e-16 58.4 0.1 2.1e-15 56.7 0.1 1.9 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Chromo PF00385.24 OAG45300.1 - 0.03 14.2 0.3 0.092 12.7 0.3 1.9 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Spc7 PF08317.11 OAG45300.1 - 0.046 12.6 40.7 0.56 9.0 11.0 3.4 2 1 1 3 3 3 0 Spc7 kinetochore protein Biopterin_H PF00351.21 OAG45300.1 - 0.12 11.4 0.2 0.28 10.2 0.2 1.6 1 0 0 1 1 1 0 Biopterin-dependent aromatic amino acid hydroxylase GAS PF13851.6 OAG45300.1 - 0.17 11.3 42.7 0.23 10.8 12.4 3.5 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding LPP PF04728.13 OAG45300.1 - 0.2 12.1 12.5 0.76 10.2 1.4 3.5 3 0 0 3 3 3 0 Lipoprotein leucine-zipper DUF3573 PF12097.8 OAG45300.1 - 0.55 9.0 2.2 1.3 7.7 2.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) HOOK PF05622.12 OAG45300.1 - 5.6 5.0 37.2 13 3.8 37.2 1.5 1 0 0 1 1 1 0 HOOK protein Sec34 PF04136.15 OAG45300.1 - 6.7 6.6 21.8 0.44 10.4 2.4 3.3 2 1 1 3 3 3 0 Sec34-like family CENP-F_leu_zip PF10473.9 OAG45300.1 - 9.8 6.2 38.0 0.32 11.0 10.6 3.5 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FMO-like PF00743.19 OAG45301.1 - 2.2e-41 141.9 0.0 6.1e-27 94.2 0.0 3.0 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OAG45301.1 - 9.9e-13 48.0 2.6 1.9e-08 33.9 0.2 3.4 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAG45301.1 - 3e-10 39.8 0.1 9.7e-09 34.9 0.2 2.5 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAG45301.1 - 9e-09 35.5 1.2 8.3e-07 29.1 0.2 3.4 3 1 0 3 3 3 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 OAG45301.1 - 1.4e-08 34.2 0.9 8.4e-07 28.4 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 OAG45301.1 - 2.8e-06 27.2 2.8 0.032 13.8 0.5 3.4 3 1 0 3 3 3 2 FAD dependent oxidoreductase Thi4 PF01946.17 OAG45301.1 - 4e-06 26.3 0.6 0.027 13.7 0.1 2.4 2 0 0 2 2 2 2 Thi4 family NAD_binding_8 PF13450.6 OAG45301.1 - 3.3e-05 24.0 0.4 0.00012 22.2 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 OAG45301.1 - 0.035 14.6 0.4 1.1 9.8 0.2 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAG45301.1 - 0.04 12.6 0.8 3.1 6.4 0.2 2.9 2 1 1 3 3 3 0 HI0933-like protein Phage_P2_GpE PF06528.12 OAG45301.1 - 0.095 12.3 0.1 9.5 5.9 0.0 2.5 2 0 0 2 2 2 0 Phage P2 GpE Abhydrolase_5 PF12695.7 OAG45302.1 - 0.0069 16.2 0.0 0.027 14.3 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 OAG45302.1 - 0.024 14.7 0.0 0.067 13.3 0.0 1.7 1 0 0 1 1 1 0 TAP-like protein COG4 PF08318.12 OAG45302.1 - 0.11 11.5 0.1 0.24 10.4 0.1 1.4 1 0 0 1 1 1 0 COG4 transport protein APH PF01636.23 OAG45305.1 - 0.001 19.0 0.0 0.0012 18.8 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 OAG45305.1 - 0.012 14.9 0.0 0.015 14.7 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PhzC-PhzF PF02567.16 OAG45307.1 - 2e-34 119.3 0.0 2.8e-34 118.9 0.0 1.1 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Pro_racemase PF05544.11 OAG45307.1 - 7.4e-06 25.2 0.1 1.6e-05 24.1 0.0 1.5 2 0 0 2 2 2 1 Proline racemase SnoaL_4 PF13577.6 OAG45308.1 - 0.039 14.1 0.0 0.051 13.7 0.0 1.3 1 1 0 1 1 1 0 SnoaL-like domain SnoaL_2 PF12680.7 OAG45308.1 - 0.1 13.3 0.0 0.2 12.3 0.0 1.7 1 1 0 1 1 1 0 SnoaL-like domain UPF0061 PF02696.14 OAG45309.1 - 4.1e-126 421.5 0.0 5.6e-126 421.0 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family LST1 PF05083.13 OAG45309.1 - 0.054 13.8 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 LST-1 protein GAS PF13851.6 OAG45310.1 - 2.3e-07 30.4 281.6 0.001 18.4 11.9 14.7 1 1 11 13 13 13 7 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 OAG45310.1 - 8.8e-07 28.1 325.3 0.00023 20.2 24.2 14.1 1 1 14 15 15 15 11 Spc7 kinetochore protein Myosin_tail_1 PF01576.19 OAG45310.1 - 0.0016 16.4 23.3 0.0016 16.4 23.3 7.1 1 1 3 6 6 6 3 Myosin tail DHR10 PF18595.1 OAG45310.1 - 0.0018 18.3 17.7 0.0018 18.3 17.7 18.6 2 1 17 19 19 19 6 Designed helical repeat protein 10 domain YqjK PF13997.6 OAG45310.1 - 0.41 10.9 2.0 10 6.4 0.0 4.2 3 0 0 3 3 3 0 YqjK-like protein Amidohydro_2 PF04909.14 OAG45311.1 - 3.2e-35 122.3 0.0 4.3e-35 121.9 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase RNR_N PF08343.10 OAG45311.1 - 0.2 11.7 0.4 8 6.6 0.0 2.2 2 0 0 2 2 2 0 Ribonucleotide reductase N-terminal Fungal_trans PF04082.18 OAG45312.1 - 3.8e-17 62.2 0.1 6.6e-17 61.4 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG45312.1 - 3.1e-05 24.0 9.7 5.2e-05 23.3 9.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cyclase PF04199.13 OAG45312.1 - 0.12 12.7 0.1 0.31 11.3 0.1 1.7 1 1 0 1 1 1 0 Putative cyclase Sugar_tr PF00083.24 OAG45313.1 - 1e-83 281.7 28.5 1.2e-83 281.5 28.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG45313.1 - 2e-17 63.2 41.8 4.4e-12 45.6 22.8 2.5 1 1 2 3 3 3 2 Major Facilitator Superfamily Dabb PF07876.12 OAG45314.1 - 1.1e-18 67.6 0.1 1.3e-18 67.4 0.1 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain DUF5039 PF16442.5 OAG45315.1 - 0.069 12.7 0.1 0.095 12.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5039) PhyH PF05721.13 OAG45316.1 - 1.5e-11 45.0 0.0 2.2e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Acyl_transf_3 PF01757.22 OAG45317.1 - 3.6e-27 95.3 32.6 1.2e-26 93.6 32.6 1.7 1 1 0 1 1 1 1 Acyltransferase family Meth_synt_2 PF01717.18 OAG45318.1 - 6.8e-13 48.6 0.0 1.5e-12 47.4 0.0 1.5 1 1 0 1 1 1 1 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 OAG45318.1 - 0.0007 19.2 0.0 0.058 12.9 0.0 2.2 2 0 0 2 2 2 2 Cobalamin-independent synthase, N-terminal domain RTA1 PF04479.13 OAG45319.1 - 1.5e-20 73.7 9.1 4.5e-20 72.2 9.1 1.6 1 1 0 1 1 1 1 RTA1 like protein GAS PF13851.6 OAG45321.1 - 0.00055 19.3 6.4 0.00072 19.0 6.4 1.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Cep57_CLD_2 PF14197.6 OAG45321.1 - 0.0024 17.9 2.5 0.0024 17.9 2.5 1.5 2 0 0 2 2 2 1 Centrosome localisation domain of PPC89 bZIP_1 PF00170.21 OAG45321.1 - 0.0053 16.8 14.3 0.01 15.9 13.1 1.8 1 1 1 2 2 2 1 bZIP transcription factor DUF3450 PF11932.8 OAG45321.1 - 0.035 13.4 3.5 0.045 13.1 3.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) RhoGAP PF00620.27 OAG45321.1 - 0.1 12.5 0.1 0.14 12.0 0.1 1.3 1 0 0 1 1 1 0 RhoGAP domain PI_PP_I PF18363.1 OAG45321.1 - 0.13 12.4 0.1 0.18 12.0 0.1 1.2 1 0 0 1 1 1 0 Phosphoinositide phosphatase insertion domain ABC_tran_CTD PF16326.5 OAG45321.1 - 0.6 10.4 5.8 0.27 11.5 3.0 1.8 1 1 1 2 2 2 0 ABC transporter C-terminal domain bZIP_Maf PF03131.17 OAG45321.1 - 0.71 10.4 11.9 1.3 9.6 11.9 1.4 1 1 0 1 1 1 0 bZIP Maf transcription factor bZIP_2 PF07716.15 OAG45321.1 - 3.1 7.9 13.3 1.6 8.9 9.2 2.0 2 0 0 2 2 2 0 Basic region leucine zipper PIG-P PF08510.12 OAG45322.1 - 5.6e-52 174.8 0.1 1.6e-51 173.3 0.1 1.8 1 1 0 1 1 1 1 PIG-P Lin-8 PF03353.15 OAG45322.1 - 0.088 12.4 1.0 0.12 11.9 0.1 1.6 1 1 1 2 2 2 0 Ras-mediated vulval-induction antagonist DPM2 PF07297.12 OAG45322.1 - 0.79 10.1 10.5 1.4 9.3 10.5 1.3 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) Peptidase_S28 PF05577.12 OAG45324.1 - 1.9e-46 158.8 0.5 1.1e-37 129.9 0.0 2.0 2 0 0 2 2 2 2 Serine carboxypeptidase S28 adh_short PF00106.25 OAG45325.1 - 3.8e-34 117.9 0.0 8.6e-34 116.7 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG45325.1 - 1.4e-30 106.6 0.2 6.9e-30 104.3 0.2 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG45325.1 - 8.2e-08 32.4 0.5 1.6e-05 24.9 0.1 2.2 2 0 0 2 2 2 2 KR domain Peptidase_M19 PF01244.21 OAG45325.1 - 0.11 11.6 0.0 0.19 10.9 0.0 1.4 1 0 0 1 1 1 0 Membrane dipeptidase (Peptidase family M19) p450 PF00067.22 OAG45326.1 - 4.2e-54 184.0 0.0 4.8e-54 183.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SnoaL PF07366.12 OAG45327.1 - 0.089 12.6 0.0 0.2 11.5 0.0 1.5 2 0 0 2 2 2 0 SnoaL-like polyketide cyclase FAD_binding_3 PF01494.19 OAG45328.1 - 1.1e-62 212.3 0.0 1.5e-62 211.9 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 OAG45328.1 - 7.9e-06 26.0 0.0 1.6e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain DAO PF01266.24 OAG45328.1 - 0.00014 21.5 0.1 0.0012 18.5 0.0 2.3 2 1 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG45328.1 - 0.0007 18.9 0.1 0.0033 16.7 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAG45328.1 - 0.0026 18.3 0.0 0.018 15.6 0.0 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG45328.1 - 0.026 14.8 0.0 0.078 13.2 0.0 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Amidohydro_1 PF01979.20 OAG45329.1 - 2.1e-23 83.2 0.0 3.3e-23 82.6 0.0 1.3 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 OAG45329.1 - 1.4e-11 44.6 0.0 6.7e-06 25.8 0.0 2.7 3 0 0 3 3 3 2 Amidohydrolase family Usp PF00582.26 OAG45329.1 - 0.12 12.9 0.1 0.42 11.1 0.2 1.8 2 0 0 2 2 2 0 Universal stress protein family Preseq_ALAS PF09029.10 OAG45329.1 - 0.18 12.3 0.0 0.35 11.4 0.0 1.4 1 0 0 1 1 1 0 5-aminolevulinate synthase presequence 2OG-FeII_Oxy PF03171.20 OAG45331.1 - 1.8e-12 47.6 0.0 3.7e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 OAG45331.1 - 2.3e-08 34.8 0.0 5.6e-08 33.5 0.0 1.7 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Sugar_tr PF00083.24 OAG45332.1 - 4.6e-86 289.5 15.4 5.4e-86 289.2 15.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG45332.1 - 1e-28 100.3 19.5 1e-28 100.3 19.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 OAG45332.1 - 2.1 6.7 11.6 0.022 13.2 1.3 2.0 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) ABA_WDS PF02496.16 OAG45333.1 - 0.00035 21.0 5.7 0.00035 21.0 5.7 3.1 1 1 2 3 3 3 1 ABA/WDS induced protein SelP_N PF04592.14 OAG45333.1 - 0.18 11.2 8.6 0.22 10.9 8.6 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region HSP20 PF00011.21 OAG45334.1 - 6.2e-08 32.7 0.0 1.5e-06 28.3 0.0 2.4 2 0 0 2 2 2 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 OAG45334.1 - 0.093 12.3 0.0 0.21 11.2 0.0 1.6 1 0 0 1 1 1 0 HSP20-like domain found in ArsA Zip PF02535.22 OAG45334.1 - 0.71 9.0 4.8 0.97 8.6 4.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Ank PF00023.30 OAG45335.1 - 0.0029 18.0 0.2 0.03 14.8 0.0 2.8 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 OAG45335.1 - 0.0063 16.8 0.0 0.042 14.2 0.0 2.4 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Helo_like_N PF17111.5 OAG45335.1 - 0.016 14.6 0.2 0.026 13.9 0.2 1.2 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins Ank_4 PF13637.6 OAG45335.1 - 0.019 15.5 0.1 0.29 11.8 0.0 2.9 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 OAG45335.1 - 0.038 14.6 0.0 3.7 8.2 0.0 3.3 3 0 0 3 3 3 0 Ankyrin repeats (3 copies) DUF2985 PF11204.8 OAG45336.1 - 1.8e-21 76.1 3.2 3.3e-21 75.2 3.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) Dicty_REP PF05086.12 OAG45336.1 - 2.7 5.9 5.0 3.8 5.4 5.0 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein PhyH PF05721.13 OAG45337.1 - 1.7e-26 93.8 0.0 2.4e-26 93.3 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) UDPG_MGDP_dh_N PF03721.14 OAG45338.1 - 3.3e-44 150.7 0.0 3.1e-28 98.6 0.0 2.3 2 0 0 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.19 OAG45338.1 - 6.3e-32 109.7 0.0 1.1e-31 108.9 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.15 OAG45338.1 - 5.6e-22 78.2 0.0 8.3e-19 68.0 0.0 2.5 2 0 0 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain ApbA PF02558.16 OAG45338.1 - 0.03 14.0 0.0 0.052 13.2 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Sacchrp_dh_NADP PF03435.18 OAG45338.1 - 0.034 14.4 0.0 0.077 13.3 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_2 PF03446.15 OAG45338.1 - 0.044 14.0 0.0 8.8 6.5 0.0 2.5 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Cellsynth_D PF03500.13 OAG45338.1 - 0.058 13.3 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Cellulose synthase subunit D 3HCDH_N PF02737.18 OAG45338.1 - 0.086 12.7 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 OAG45338.1 - 0.14 12.1 0.0 17 5.3 0.0 3.2 3 0 0 3 3 3 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Glycos_transf_1 PF00534.20 OAG45339.1 - 3.1e-34 118.0 0.0 4.6e-34 117.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 OAG45339.1 - 4.1e-29 101.7 0.0 9.6e-29 100.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 OAG45339.1 - 2.4e-13 50.4 0.0 6.5e-13 49.0 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 OAG45339.1 - 9.9e-13 48.8 0.0 3.2e-12 47.2 0.0 1.9 1 1 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 OAG45339.1 - 1.3e-08 35.1 0.0 2.7e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.6 OAG45339.1 - 0.012 15.7 0.0 0.024 14.6 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase 4-like GlgS PF08971.11 OAG45339.1 - 0.045 13.8 0.0 0.094 12.8 0.0 1.4 1 0 0 1 1 1 0 Glycogen synthesis protein Fungal_trans_2 PF11951.8 OAG45340.1 - 9.1e-13 47.8 0.1 1.3e-12 47.3 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Tau95_N PF17682.1 OAG45341.1 - 9.4e-35 119.6 0.0 1.3e-34 119.2 0.0 1.2 1 0 0 1 1 1 1 Tau95 Triple barrel domain B56 PF01603.20 OAG45342.1 - 4.6e-191 635.2 8.5 4.6e-191 635.2 8.5 3.6 3 0 0 3 3 3 2 Protein phosphatase 2A regulatory B subunit (B56 family) FAT PF02259.23 OAG45342.1 - 2.7e-73 247.2 9.8 5.4e-73 246.2 9.8 1.6 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.27 OAG45342.1 - 1.3e-31 110.3 0.4 4.5e-31 108.6 0.1 2.2 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 OAG45342.1 - 2.6e-06 27.1 0.1 6.2e-06 25.9 0.1 1.7 1 0 0 1 1 1 1 FATC domain ANAPC3 PF12895.7 OAG45343.1 - 3.8e-22 78.3 19.2 9.2e-21 73.9 0.7 5.5 5 1 0 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 OAG45343.1 - 5.5e-20 69.8 20.2 0.0089 16.1 0.1 9.5 10 0 0 10 10 9 6 Tetratricopeptide repeat TPR_19 PF14559.6 OAG45343.1 - 1.5e-18 67.0 10.2 0.00036 21.0 0.0 6.0 5 1 1 6 6 6 5 Tetratricopeptide repeat TPR_1 PF00515.28 OAG45343.1 - 8.7e-18 63.3 15.0 0.003 17.3 0.1 8.1 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_12 PF13424.6 OAG45343.1 - 4.3e-15 55.8 23.4 2.6e-08 34.0 0.1 9.1 8 2 2 10 10 10 3 Tetratricopeptide repeat TPR_16 PF13432.6 OAG45343.1 - 3.3e-10 40.4 17.7 0.29 11.8 1.4 7.1 6 1 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 OAG45343.1 - 3.5e-10 39.3 9.5 0.11 12.8 0.0 7.1 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_14 PF13428.6 OAG45343.1 - 1.9e-09 37.6 14.7 0.43 11.5 0.4 9.5 9 2 2 11 11 10 2 Tetratricopeptide repeat TPR_11 PF13414.6 OAG45343.1 - 2.6e-09 36.6 0.9 0.35 10.6 0.1 6.3 6 0 0 6 6 6 1 TPR repeat TPR_10 PF13374.6 OAG45343.1 - 3.1e-09 36.4 12.3 8.9e-05 22.2 0.2 7.4 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_7 PF13176.6 OAG45343.1 - 1.5e-08 34.1 10.5 0.53 10.4 0.0 7.5 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_6 PF13174.6 OAG45343.1 - 1e-06 29.0 8.0 0.89 10.3 0.1 6.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 OAG45343.1 - 0.013 15.8 2.1 32 5.2 0.0 6.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.14 OAG45343.1 - 0.037 14.6 0.5 0.037 14.6 0.5 5.8 6 0 0 6 6 4 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 OAG45343.1 - 2.8 8.1 8.5 8.2 6.6 0.4 4.0 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat DUF572 PF04502.13 OAG45344.1 - 8.9e-70 235.9 19.7 1.1e-69 235.7 19.7 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) zf-ACC PF17848.1 OAG45344.1 - 0.22 11.7 4.0 0.7 10.0 1.0 2.5 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain TF_Zn_Ribbon PF08271.12 OAG45344.1 - 5 6.7 6.2 3.6 7.2 1.6 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding V_ATPase_I PF01496.19 OAG45344.1 - 9 4.1 8.6 10 3.9 8.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family adh_short PF00106.25 OAG45345.1 - 4.4e-41 140.5 0.0 6.3e-41 140.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG45345.1 - 5.6e-28 98.1 0.0 8.8e-28 97.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG45345.1 - 4.7e-08 33.2 0.0 1e-07 32.1 0.0 1.5 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 OAG45345.1 - 0.0009 19.2 0.1 0.0015 18.5 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 OAG45345.1 - 0.0023 17.1 0.0 0.0039 16.3 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 OAG45345.1 - 0.026 14.0 0.0 0.044 13.2 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family TRI12 PF06609.13 OAG45348.1 - 5.3e-38 130.8 23.6 6.8e-38 130.5 23.6 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG45348.1 - 3e-19 69.2 42.2 3e-19 69.2 42.2 2.3 2 1 0 2 2 2 2 Major Facilitator Superfamily HEPN_AbiU2 PF18734.1 OAG45349.1 - 0.0031 17.1 0.9 0.011 15.2 0.0 2.1 2 0 0 2 2 2 1 AbiU2 APH PF01636.23 OAG45350.1 - 3.2e-15 56.7 0.0 7.7e-15 55.5 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 OAG45350.1 - 0.052 13.1 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Fructosamin_kin PF03881.14 OAG45350.1 - 0.18 10.9 0.0 0.28 10.4 0.0 1.2 1 0 0 1 1 1 0 Fructosamine kinase Tannase PF07519.11 OAG45351.1 - 1.2e-95 321.2 0.0 1.4e-95 320.9 0.0 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.21 OAG45351.1 - 9.4e-05 22.0 0.1 0.46 9.9 0.1 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 OAG45351.1 - 0.023 13.9 0.0 0.16 11.2 0.0 2.0 2 0 0 2 2 2 0 Serine aminopeptidase, S33 GST_N_2 PF13409.6 OAG45352.1 - 3.3e-14 52.9 0.1 1.2e-13 51.1 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 OAG45352.1 - 8.1e-14 51.8 0.0 2.2e-13 50.4 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 OAG45352.1 - 3.3e-08 33.8 0.0 1.8e-07 31.4 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 OAG45352.1 - 6.2e-06 26.3 0.0 1.5e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 Glutaredoxin GST_C_5 PF16865.5 OAG45352.1 - 0.0016 19.0 0.1 0.0048 17.4 0.1 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Thi4 PF01946.17 OAG45353.1 - 1.9e-115 384.0 0.0 2.3e-115 383.8 0.0 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 OAG45353.1 - 5e-08 32.9 1.2 4e-07 29.9 0.9 2.0 1 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAG45353.1 - 2.3e-06 27.8 0.3 7.6e-06 26.1 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 OAG45353.1 - 8.7e-06 25.0 0.3 1.8e-05 24.0 0.3 1.7 1 1 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 OAG45353.1 - 1.5e-05 24.4 0.1 3.6e-05 23.2 0.1 1.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAG45353.1 - 6.2e-05 22.2 1.4 0.0036 16.5 0.6 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.6 OAG45353.1 - 0.0013 18.8 1.5 0.0017 18.4 0.0 2.0 3 0 0 3 3 3 1 FAD-NAD(P)-binding FAD_oxidored PF12831.7 OAG45353.1 - 0.019 14.3 0.1 0.025 13.9 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 OAG45353.1 - 0.021 14.1 0.0 0.031 13.5 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 OAG45353.1 - 0.035 13.4 0.0 0.053 12.8 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAG45353.1 - 0.055 12.2 0.2 0.08 11.6 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein Trp_halogenase PF04820.14 OAG45353.1 - 0.13 11.1 0.2 0.2 10.4 0.2 1.2 1 0 0 1 1 1 0 Tryptophan halogenase K_oxygenase PF13434.6 OAG45353.1 - 0.22 10.7 0.0 0.35 10.0 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) MFS_1 PF07690.16 OAG45354.1 - 2.2e-36 125.5 49.4 5.1e-36 124.3 49.4 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG45354.1 - 1.2e-10 40.9 8.0 1.2e-10 40.9 8.0 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 OAG45354.1 - 0.14 10.4 12.5 3.2 5.9 11.2 2.7 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Mpv17_PMP22 PF04117.12 OAG45356.1 - 2.3e-16 59.8 0.1 4e-16 59.0 0.1 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family ECH_1 PF00378.20 OAG45357.1 - 1.2e-50 172.2 0.0 1.5e-50 171.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAG45357.1 - 3.3e-23 82.7 0.0 2.1e-21 76.8 0.0 2.2 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 OAG45357.1 - 0.0082 16.1 0.0 0.069 13.1 0.0 2.1 2 0 0 2 2 2 1 Peptidase family S49 DUF3005 PF11448.8 OAG45357.1 - 0.043 13.9 0.1 2.1 8.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3005) PfkB PF00294.24 OAG45358.1 - 4.9e-38 131.1 0.1 6.7e-38 130.7 0.1 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Caleosin PF05042.13 OAG45359.1 - 2.6e-62 209.7 0.1 3.3e-62 209.4 0.1 1.1 1 0 0 1 1 1 1 Caleosin related protein EF-hand_6 PF13405.6 OAG45359.1 - 0.00034 20.3 3.4 0.0016 18.2 0.2 2.8 3 0 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.6 OAG45359.1 - 0.004 17.6 0.0 0.018 15.5 0.0 2.1 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 OAG45359.1 - 0.0095 15.4 3.2 0.51 10.0 0.4 2.6 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 OAG45359.1 - 0.012 15.1 1.9 0.12 11.9 0.1 2.4 2 0 0 2 2 2 0 EF hand EF-hand_8 PF13833.6 OAG45359.1 - 0.072 12.9 0.1 4.3 7.3 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain pair CAP PF00188.26 OAG45360.1 - 4.6e-19 69.5 1.1 4.6e-19 69.5 1.1 1.8 2 0 0 2 2 2 1 Cysteine-rich secretory protein family Carn_acyltransf PF00755.20 OAG45361.1 - 9.7e-212 704.7 0.0 1.9e-211 703.8 0.0 1.4 1 1 0 1 1 1 1 Choline/Carnitine o-acyltransferase DUF3829 PF12889.7 OAG45361.1 - 0.17 11.4 2.2 6 6.3 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3829) JmjC PF02373.22 OAG45362.1 - 4.3e-36 123.8 0.4 1.2e-35 122.4 0.4 1.8 1 0 0 1 1 1 1 JmjC domain, hydroxylase zf-HC5HC2H_2 PF13832.6 OAG45362.1 - 3.4e-19 69.0 8.5 7.3e-19 68.0 8.5 1.5 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 OAG45362.1 - 1.3e-17 63.8 8.2 1.3e-17 63.8 8.2 2.4 2 0 0 2 2 2 1 PHD-like zinc-binding domain JmjN PF02375.17 OAG45362.1 - 1.5e-09 37.7 0.1 4e-09 36.3 0.1 1.9 1 0 0 1 1 1 1 jmjN domain AT_hook PF02178.19 OAG45362.1 - 1.2 9.2 20.0 0.62 10.1 5.8 3.0 2 0 0 2 2 2 0 AT hook motif Pkinase PF00069.25 OAG45364.1 - 9.5e-13 48.1 0.0 1.7e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG45364.1 - 2.5e-05 23.7 0.0 3.8e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OAG45364.1 - 0.0021 17.4 0.0 0.0037 16.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OAG45364.1 - 0.011 15.7 1.9 0.021 14.8 0.4 2.0 2 1 1 3 3 3 0 Phosphotransferase enzyme family RIO1 PF01163.22 OAG45364.1 - 0.012 15.2 0.0 0.02 14.5 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Seadorna_VP7 PF07387.11 OAG45364.1 - 0.018 14.1 0.3 0.045 12.8 0.3 1.6 1 1 0 1 1 1 0 Seadornavirus VP7 Clr5 PF14420.6 OAG45366.1 - 2.2e-07 31.0 1.4 4.5e-07 30.0 1.4 1.6 1 0 0 1 1 1 1 Clr5 domain TPR_1 PF00515.28 OAG45366.1 - 0.00029 20.5 0.3 0.0036 17.0 0.0 2.5 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 OAG45366.1 - 0.00035 20.6 0.0 0.12 12.6 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 OAG45366.1 - 0.002 18.7 0.1 0.0053 17.4 0.1 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 OAG45366.1 - 0.0031 17.5 0.3 0.011 15.8 0.0 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 OAG45366.1 - 0.0093 16.2 0.3 0.053 13.8 0.3 2.4 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 OAG45366.1 - 0.014 15.4 0.2 0.09 12.9 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 OAG45366.1 - 0.016 15.1 1.2 0.38 10.7 0.3 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_MalT PF17874.1 OAG45366.1 - 0.019 14.4 0.0 0.035 13.5 0.0 1.5 1 0 0 1 1 1 0 MalT-like TPR region TPR_19 PF14559.6 OAG45366.1 - 0.072 13.6 0.1 0.26 11.8 0.1 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 OAG45366.1 - 0.14 13.0 0.1 0.66 11.0 0.1 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat Glyco_transf_25 PF01755.17 OAG45367.1 - 1.2e-06 28.5 0.0 2.2e-05 24.4 0.0 2.2 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) Glyco_transf_34 PF05637.12 OAG45368.1 - 5.5e-14 52.5 0.0 1.6e-06 28.1 0.0 2.3 1 1 1 2 2 2 2 galactosyl transferase GMA12/MNN10 family RNA_pol_3_Rpc31 PF11705.8 OAG45368.1 - 0.16 12.2 6.3 0.26 11.5 6.3 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Glyco_tranf_2_4 PF13704.6 OAG45368.1 - 0.22 12.0 1.5 3.5 8.2 0.8 3.1 2 1 0 2 2 2 0 Glycosyl transferase family 2 SDA1 PF05285.12 OAG45368.1 - 0.24 10.8 6.8 0.057 12.8 3.7 1.4 2 0 0 2 2 2 0 SDA1 TPT PF03151.16 OAG45369.1 - 4.7e-12 45.8 19.9 5.8e-12 45.5 19.9 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 OAG45369.1 - 9.7e-07 29.0 33.6 1e-06 28.9 11.5 2.3 2 0 0 2 2 2 2 EamA-like transporter family PI3_PI4_kinase PF00454.27 OAG45370.1 - 1e-37 130.3 0.0 1.4e-35 123.3 0.0 2.4 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 OAG45370.1 - 2.7e-23 82.3 0.1 6.3e-23 81.1 0.1 1.7 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Stealth_CR2 PF11380.8 OAG45370.1 - 1.2e-15 57.6 0.1 5.9e-15 55.4 0.1 2.3 1 0 0 1 1 1 1 Stealth protein CR2, conserved region 2 Stealth_CR1 PF17101.5 OAG45370.1 - 1e-07 31.5 0.2 2.6e-07 30.3 0.2 1.7 1 0 0 1 1 1 1 Stealth protein CR1, conserved region 1 Stealth_CR4 PF17103.5 OAG45370.1 - 0.0088 15.9 0.0 0.024 14.5 0.0 1.7 1 0 0 1 1 1 1 Stealth protein CR4, conserved region 4 Stealth_CR3 PF17102.5 OAG45370.1 - 0.015 15.2 0.3 0.072 13.0 0.1 2.3 2 0 0 2 2 2 0 Stealth protein CR3, conserved region 3 DUF4135 PF13575.6 OAG45370.1 - 0.11 11.7 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) DUF812 PF05667.11 OAG45371.1 - 0.057 12.3 23.6 0.099 11.5 23.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF812) GAS PF13851.6 OAG45371.1 - 0.1 11.9 39.3 0.14 11.5 17.7 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding V_ATPase_I PF01496.19 OAG45371.1 - 1.1 7.1 11.5 1.5 6.7 11.5 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ax_dynein_light PF10211.9 OAG45371.1 - 2.2 8.2 34.7 0.46 10.4 7.4 2.5 1 1 1 2 2 2 0 Axonemal dynein light chain FUSC PF04632.12 OAG45371.1 - 5 5.5 6.6 7.2 5.0 6.6 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family LMBR1 PF04791.16 OAG45371.1 - 9.9 4.9 13.4 14 4.4 13.4 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein MmgE_PrpD PF03972.14 OAG45372.1 - 3.6e-120 401.5 9.5 4.7e-120 401.1 9.5 1.1 1 0 0 1 1 1 1 MmgE/PrpD family Zn_clus PF00172.18 OAG45373.1 - 1.2e-07 31.7 3.6 2.5e-07 30.7 3.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Prot_inhib_II PF02428.15 OAG45373.1 - 1.5 9.3 5.0 24 5.5 0.4 2.5 2 0 0 2 2 2 0 Potato type II proteinase inhibitor family Utp13 PF08625.11 OAG45374.1 - 6.2e-48 162.3 0.0 1.5e-47 161.1 0.0 1.7 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain WD40 PF00400.32 OAG45374.1 - 9.2e-48 159.2 22.9 8.7e-05 23.2 0.6 13.9 12 4 0 12 12 12 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG45374.1 - 1.1e-08 35.3 1.7 2.1 8.7 0.1 7.6 5 3 2 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OAG45374.1 - 2.8e-07 29.6 11.5 0.66 8.5 0.1 7.1 5 2 3 8 8 8 5 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 OAG45374.1 - 0.0034 16.4 1.2 1.3 7.9 0.1 4.0 5 1 0 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 OAG45374.1 - 0.0035 16.2 3.5 0.21 10.3 0.4 3.9 4 1 1 5 5 5 1 Nup133 N terminal like PALB2_WD40 PF16756.5 OAG45374.1 - 0.06 12.3 0.4 13 4.6 0.0 3.7 3 0 0 3 3 3 0 Partner and localizer of BRCA2 WD40 domain G-patch_2 PF12656.7 OAG45375.1 - 2.4e-15 56.4 0.3 2.4e-15 56.4 0.3 2.5 3 0 0 3 3 3 1 G-patch domain zf-C3HC4_3 PF13920.6 OAG45376.1 - 1.4e-06 28.0 8.5 1.4e-06 28.0 8.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAG45376.1 - 1.6e-06 28.1 8.5 1.6e-06 28.1 8.5 1.8 2 0 0 2 2 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 OAG45376.1 - 4.7e-06 26.6 11.6 4.7e-06 26.6 11.6 2.5 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 OAG45376.1 - 6.2e-06 26.0 11.2 6.2e-06 26.0 11.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAG45376.1 - 8.7e-06 26.0 10.7 8.7e-06 26.0 10.7 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 OAG45376.1 - 1.9e-05 24.4 10.3 1.9e-05 24.4 10.3 2.5 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAG45376.1 - 0.00012 21.9 10.1 0.00012 21.9 10.1 2.3 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 OAG45376.1 - 0.00036 20.3 11.8 0.001 18.9 7.6 2.4 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 OAG45376.1 - 1.4 8.7 5.7 6.2 6.7 5.7 2.2 1 0 0 1 1 1 0 RING-like zinc finger zf-ANAPC11 PF12861.7 OAG45376.1 - 1.7 8.8 5.5 0.28 11.3 1.4 1.9 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger DZR PF12773.7 OAG45376.1 - 6 7.0 15.1 1.7 8.7 0.6 2.9 2 1 0 2 2 2 0 Double zinc ribbon Proteasome PF00227.26 OAG45377.1 - 1.8e-16 60.2 0.0 2e-16 60.0 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit WD40 PF00400.32 OAG45378.1 - 1.3e-16 60.7 8.4 4.3e-06 27.3 0.0 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG45378.1 - 0.0068 16.7 0.0 0.062 13.6 0.0 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Abhydrolase_6 PF12697.7 OAG45380.1 - 1.8e-17 64.7 8.7 2.1e-17 64.5 8.7 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAG45380.1 - 3.3e-14 53.1 0.1 5.3e-14 52.5 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAG45380.1 - 3.4e-08 33.0 0.4 1.9e-07 30.6 0.4 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 OAG45380.1 - 0.0012 18.5 0.0 0.0043 16.7 0.0 1.9 3 0 0 3 3 3 1 Putative esterase Palm_thioest PF02089.15 OAG45380.1 - 0.0036 17.2 0.0 0.0044 16.9 0.0 1.1 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Chlorophyllase2 PF12740.7 OAG45380.1 - 0.0038 16.2 0.0 0.021 13.7 0.0 1.9 1 1 0 1 1 1 1 Chlorophyllase enzyme UPF0227 PF05728.12 OAG45380.1 - 0.01 15.8 0.0 0.019 14.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Thioesterase PF00975.20 OAG45380.1 - 0.015 15.4 0.1 0.026 14.6 0.1 1.4 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_5 PF12695.7 OAG45380.1 - 0.038 13.7 0.0 0.74 9.6 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase family DUF3141 PF11339.8 OAG45380.1 - 0.13 10.7 0.0 0.18 10.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3141) Abhydrolase_2 PF02230.16 OAG45380.1 - 0.14 12.0 0.0 5.3 6.8 0.1 2.5 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase SAM_2 PF07647.17 OAG45381.1 - 2.2e-09 37.3 0.0 4e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 OAG45381.1 - 4.2e-09 36.7 0.0 1.3e-08 35.2 0.0 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) PH PF00169.29 OAG45381.1 - 3.1e-07 30.9 0.1 5.8e-07 30.0 0.1 1.5 1 0 0 1 1 1 1 PH domain SAM_3 PF18016.1 OAG45381.1 - 0.0026 17.5 0.0 0.0055 16.5 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) HTH_32 PF13565.6 OAG45381.1 - 0.25 12.0 5.3 1.9 9.2 0.0 3.8 3 0 0 3 3 3 0 Homeodomain-like domain Fungal_trans_2 PF11951.8 OAG45382.1 - 7.5e-75 252.1 0.2 1.1e-74 251.5 0.0 1.4 2 0 0 2 2 2 1 Fungal specific transcription factor domain Med3 PF11593.8 OAG45382.1 - 0.29 10.3 7.2 0.63 9.2 7.2 1.5 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal NMO PF03060.15 OAG45383.1 - 2.7e-50 171.7 2.2 4e-50 171.1 2.2 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 OAG45383.1 - 1.3e-05 24.4 0.3 0.0028 16.7 0.1 2.6 2 1 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 OAG45383.1 - 0.0003 19.9 4.0 0.00043 19.4 4.0 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 OAG45383.1 - 0.0034 16.6 0.1 0.0047 16.1 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase DHO_dh PF01180.21 OAG45383.1 - 0.094 11.9 0.7 0.23 10.7 0.7 1.6 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase Abhydrolase_1 PF00561.20 OAG45385.1 - 2.9e-14 53.3 0.5 5.1e-10 39.4 0.4 2.3 2 1 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAG45385.1 - 8.5e-14 51.4 0.0 5.1e-12 45.6 0.0 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OAG45385.1 - 7.8e-12 46.3 0.0 1.1e-11 45.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 OAG45385.1 - 0.00018 21.2 0.0 0.11 12.0 0.0 2.7 2 2 1 3 3 3 2 Dienelactone hydrolase family FSH1 PF03959.13 OAG45385.1 - 0.0013 18.4 0.1 0.018 14.7 0.0 2.1 2 0 0 2 2 2 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.7 OAG45385.1 - 0.0035 17.1 0.0 1.3 8.8 0.0 2.4 2 0 0 2 2 2 2 Alpha/beta hydrolase family Esterase PF00756.20 OAG45385.1 - 0.02 14.5 0.0 0.053 13.2 0.0 1.6 1 1 0 1 1 1 0 Putative esterase BAAT_C PF08840.11 OAG45385.1 - 0.2 11.6 0.0 1.5 8.7 0.0 2.0 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal ANAPC4_WD40 PF12894.7 OAG45386.1 - 4.9e-07 30.0 0.0 0.013 15.7 0.0 3.5 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OAG45386.1 - 8e-05 23.3 5.8 0.21 12.5 0.2 5.7 5 1 0 5 5 5 1 WD domain, G-beta repeat TFIIF_alpha PF05793.12 OAG45386.1 - 0.18 10.4 8.5 0.26 9.8 8.5 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PBP1_TM PF14812.6 OAG45386.1 - 0.54 10.7 5.4 1 9.8 5.4 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal MFS_1 PF07690.16 OAG45387.1 - 4e-29 101.6 74.2 2.9e-28 98.8 42.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Bd3614-deam PF14439.6 OAG45387.1 - 5.5 7.1 6.3 18 5.4 2.1 2.2 2 0 0 2 2 2 0 Bd3614-like deaminase Fe-ADH PF00465.19 OAG45388.1 - 2.9e-79 266.5 0.4 3.4e-79 266.3 0.4 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 OAG45388.1 - 1.3e-15 57.8 0.4 1.8e-15 57.3 0.4 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase DUF1967 PF09269.11 OAG45388.1 - 0.2 11.6 0.0 0.41 10.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1967) ILVD_EDD PF00920.21 OAG45389.1 - 0.0048 15.6 0.2 0.0054 15.4 0.2 1.0 1 0 0 1 1 1 1 Dehydratase family Diphthamide_syn PF01866.17 OAG45390.1 - 2.3e-82 276.8 0.0 3.2e-82 276.4 0.0 1.2 1 0 0 1 1 1 1 Putative diphthamide synthesis protein ComA PF02679.15 OAG45391.1 - 5.7e-92 307.6 0.0 6.8e-92 307.3 0.0 1.1 1 0 0 1 1 1 1 (2R)-phospho-3-sulfolactate synthase (ComA) HMGL-like PF00682.19 OAG45391.1 - 0.12 12.0 0.0 12 5.4 0.0 2.3 1 1 1 2 2 2 0 HMGL-like Oxidored_FMN PF00724.20 OAG45391.1 - 0.2 10.9 0.0 5 6.3 0.0 2.0 2 0 0 2 2 2 0 NADH:flavin oxidoreductase / NADH oxidase family PLA2_B PF01735.18 OAG45392.1 - 9e-195 647.7 4.5 1.1e-194 647.5 4.5 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain MFS_1 PF07690.16 OAG45393.1 - 2.8e-40 138.3 36.1 2.8e-40 138.3 36.1 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 OAG45393.1 - 1.6e-08 33.5 3.5 3.3e-08 32.4 3.5 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Trp_oprn_chp PF09534.10 OAG45393.1 - 0.024 14.4 6.9 0.11 12.3 4.2 2.5 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) CLZ PF16526.5 OAG45393.1 - 0.22 11.9 0.1 0.35 11.2 0.1 1.3 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Ribophorin_II PF05817.14 OAG45394.1 - 7.6e-31 107.4 0.1 1e-30 106.9 0.1 1.1 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II FMO-like PF00743.19 OAG45395.1 - 2.8e-12 45.8 0.4 4.3e-11 41.9 0.1 2.1 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 OAG45395.1 - 1.8e-11 43.8 0.0 1.5e-09 37.5 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAG45395.1 - 4.1e-11 42.6 0.2 1e-09 38.0 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 OAG45395.1 - 6.2e-09 36.0 0.1 1.2e-07 31.9 0.0 2.8 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 OAG45395.1 - 1e-08 34.8 0.0 2.1e-08 33.8 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OAG45395.1 - 0.00077 18.6 0.1 0.0095 15.0 0.1 2.2 2 1 0 2 2 2 1 Lycopene cyclase protein Pyr_redox PF00070.27 OAG45395.1 - 0.00097 19.7 0.4 0.31 11.6 0.3 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAG45395.1 - 0.0037 17.3 0.2 0.4 10.7 0.1 3.2 3 1 0 3 3 3 1 FAD-NAD(P)-binding ThiF PF00899.21 OAG45395.1 - 0.096 12.0 0.3 7.7 5.8 0.0 2.3 2 0 0 2 2 2 0 ThiF family DAO PF01266.24 OAG45395.1 - 0.098 12.2 7.2 0.3 10.6 0.3 3.6 2 2 1 4 4 4 0 FAD dependent oxidoreductase GATase PF00117.28 OAG45396.1 - 1.9e-05 24.5 0.1 0.00014 21.7 0.0 2.0 1 1 1 2 2 2 1 Glutamine amidotransferase class-I SNO PF01174.19 OAG45396.1 - 0.013 15.4 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 SNO glutamine amidotransferase family Abhydrolase_1 PF00561.20 OAG45397.1 - 3.2e-11 43.4 0.3 1e-09 38.4 0.2 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG45397.1 - 1.4e-07 32.4 0.9 1.9e-07 31.9 0.9 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family BRF1 PF07741.13 OAG45398.1 - 0.023 15.0 1.3 0.028 14.8 1.3 1.1 1 0 0 1 1 1 0 Brf1-like TBP-binding domain UPF0560 PF10577.9 OAG45398.1 - 1.7 7.0 8.9 1.8 7.0 8.9 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Spt20 PF12090.8 OAG45398.1 - 3.4 7.2 18.1 3.9 7.0 18.1 1.1 1 0 0 1 1 1 0 Spt20 family DUF2722 PF10846.8 OAG45398.1 - 4 6.3 17.0 4.8 6.0 17.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Presenilin PF01080.17 OAG45398.1 - 6.7 5.4 4.9 7 5.3 4.9 1.0 1 0 0 1 1 1 0 Presenilin DUF4175 PF13779.6 OAG45398.1 - 6.9 4.4 17.6 6.6 4.5 17.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) adh_short PF00106.25 OAG45399.1 - 8.1e-26 90.7 0.0 1e-25 90.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG45399.1 - 9.8e-22 77.6 0.0 1.2e-21 77.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG45399.1 - 0.019 14.9 0.0 0.03 14.3 0.0 1.2 1 0 0 1 1 1 0 KR domain Abhydrolase_3 PF07859.13 OAG45400.1 - 1.4e-52 178.7 0.0 1.7e-52 178.3 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 OAG45400.1 - 2e-11 43.5 1.2 1.1e-10 41.0 1.2 1.9 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 OAG45400.1 - 1e-05 25.1 0.0 0.091 12.2 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 OAG45400.1 - 0.003 18.2 2.7 0.0055 17.3 2.7 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Say1_Mug180 PF10340.9 OAG45400.1 - 0.0041 16.0 0.0 0.0058 15.5 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase DLH PF01738.18 OAG45400.1 - 0.15 11.6 0.0 0.3 10.6 0.0 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family adh_short PF00106.25 OAG45401.1 - 4.6e-35 120.9 0.0 5.7e-35 120.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG45401.1 - 4.1e-26 92.0 0.0 5.3e-26 91.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG45401.1 - 1.1e-05 25.5 0.0 0.00047 20.1 0.0 2.1 2 0 0 2 2 2 1 KR domain ADH_zinc_N PF00107.26 OAG45401.1 - 0.13 12.3 1.2 14 5.6 0.1 3.0 2 1 1 3 3 3 0 Zinc-binding dehydrogenase Methyltransf_23 PF13489.6 OAG45401.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain 4HBT_3 PF13622.6 OAG45402.1 - 1.9e-36 126.6 0.5 2.3e-36 126.3 0.5 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 OAG45402.1 - 3.2e-13 49.7 0.1 4e-09 36.4 0.2 3.3 2 2 0 2 2 2 2 Acyl-CoA thioesterase Diphthami_syn_2 PF01902.17 OAG45403.1 - 2.6e-14 53.3 0.0 6.2e-08 32.4 0.0 4.2 2 1 0 2 2 2 2 Diphthamide synthase Ribonuc_L-PSP PF01042.21 OAG45403.1 - 3.5e-11 43.2 0.0 2e-05 24.6 0.0 3.7 5 0 0 5 5 5 2 Endoribonuclease L-PSP ThiI PF02568.14 OAG45403.1 - 0.025 14.2 0.0 0.043 13.4 0.0 1.3 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) zf-C2H2 PF00096.26 OAG45404.1 - 1.6e-12 47.2 11.8 2e-06 27.9 0.4 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OAG45404.1 - 5.1e-07 29.8 12.0 7.2e-07 29.4 4.1 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 OAG45404.1 - 4.1e-06 27.2 16.3 0.0023 18.6 0.2 3.2 3 0 0 3 3 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OAG45404.1 - 0.00013 22.2 8.1 0.011 16.0 0.5 3.4 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 OAG45404.1 - 0.00016 21.6 9.5 0.0066 16.4 0.8 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 OAG45404.1 - 0.00056 20.2 8.4 0.0071 16.7 0.3 3.0 3 0 0 3 3 2 2 Zinc-finger of C2H2 type zf_C2H2_ZHX PF18387.1 OAG45404.1 - 0.004 16.8 3.4 1.1 8.9 0.3 2.8 1 1 1 2 2 2 2 Zinc-fingers and homeoboxes C2H2 finger domain Smg4_UPF3 PF03467.15 OAG45404.1 - 0.0051 16.8 0.6 0.01 15.9 0.6 1.5 1 0 0 1 1 1 1 Smg-4/UPF3 family CNDH2_C PF16858.5 OAG45404.1 - 0.03 14.2 2.7 0.048 13.5 2.7 1.3 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term zf-BED PF02892.15 OAG45404.1 - 0.094 12.8 5.4 0.057 13.5 1.5 2.5 1 1 1 2 2 2 0 BED zinc finger zf-C2H2_3rep PF18868.1 OAG45404.1 - 0.17 12.6 2.9 2.1 9.0 0.8 2.5 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_2 PF12756.7 OAG45404.1 - 0.35 11.2 3.7 8.4 6.8 0.4 2.8 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_11 PF16622.5 OAG45404.1 - 0.63 9.8 7.8 9.5 6.1 0.0 2.5 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2HE PF16278.5 OAG45404.1 - 0.9 10.0 7.2 1.1e+02 3.3 7.2 2.6 1 1 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger zf-LYAR PF08790.11 OAG45404.1 - 0.98 9.4 5.4 16 5.5 0.1 3.1 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger PITH PF06201.13 OAG45405.1 - 1.1e-39 136.0 0.3 2.4e-39 135.0 0.0 1.6 2 0 0 2 2 2 1 PITH domain Thioredoxin PF00085.20 OAG45405.1 - 4.6e-22 77.9 0.0 1e-21 76.9 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 OAG45405.1 - 1.1e-05 25.0 0.0 3.3e-05 23.4 0.0 1.7 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 OAG45405.1 - 0.0059 17.0 0.1 0.015 15.7 0.1 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain DIM1 PF02966.16 OAG45405.1 - 0.008 16.0 0.0 0.014 15.2 0.0 1.3 1 0 0 1 1 1 1 Mitosis protein DIM1 HyaE PF07449.11 OAG45405.1 - 0.035 14.1 0.0 0.097 12.6 0.0 1.7 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Thioredoxin_8 PF13905.6 OAG45405.1 - 0.04 14.2 0.0 0.38 11.1 0.0 2.2 1 1 1 2 2 2 0 Thioredoxin-like Fungal_trans_2 PF11951.8 OAG45406.1 - 3.1e-07 29.6 2.7 5.1e-06 25.5 2.7 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain C2 PF00168.30 OAG45407.1 - 4.9e-23 81.4 0.0 1.9e-11 44.2 0.0 2.5 2 0 0 2 2 2 2 C2 domain zf-CSL PF05207.13 OAG45408.1 - 5.6e-19 67.6 1.7 8.4e-19 67.1 1.7 1.3 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.31 OAG45408.1 - 4.9e-12 45.8 1.1 4.1e-11 42.8 1.1 2.1 1 1 0 1 1 1 1 DnaJ domain SIR4_SID PF16991.5 OAG45409.1 - 0.012 15.6 2.0 0.012 15.6 2.0 1.5 1 1 0 1 1 1 0 Sir4 SID domain TetR PF13972.6 OAG45409.1 - 0.033 13.9 4.5 0.056 13.2 0.2 2.3 1 1 0 2 2 2 0 Bacterial transcriptional repressor Mu-like_Pro PF10123.9 OAG45409.1 - 0.17 11.4 5.4 0.28 10.7 5.4 1.5 1 1 0 1 1 1 0 Mu-like prophage I protein OmpH PF03938.14 OAG45409.1 - 0.22 11.8 15.2 0.093 13.1 12.5 1.6 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Baculo_PEP_C PF04513.12 OAG45409.1 - 0.73 9.9 4.3 9.9 6.2 0.9 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ZapA PF05164.13 OAG45409.1 - 1.8 9.1 7.2 0.61 10.6 3.1 2.0 1 1 1 2 2 2 0 Cell division protein ZapA DUF3086 PF11285.8 OAG45409.1 - 1.8 7.6 11.5 0.78 8.8 1.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3086) PRP1_N PF06424.12 OAG45409.1 - 2.4 8.5 9.4 5.4 7.4 3.8 2.1 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal DUF1664 PF07889.12 OAG45409.1 - 5.4 7.1 9.4 12 5.9 1.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF641 PF04859.12 OAG45409.1 - 8.7 6.7 11.8 2.9 8.3 3.4 2.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) DAGAT PF03982.13 OAG45410.1 - 1e-90 303.7 0.0 1.2e-90 303.4 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Rer1 PF03248.13 OAG45410.1 - 0.13 12.0 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Rer1 family Asp PF00026.23 OAG45411.1 - 6.6e-78 262.3 11.2 8.2e-78 262.0 11.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OAG45411.1 - 1.8e-09 38.1 3.2 0.0013 19.0 1.3 3.1 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 OAG45411.1 - 3.3e-06 27.6 1.5 0.00055 20.5 0.3 3.1 2 1 0 2 2 2 1 Aspartyl protease HMG_box PF00505.19 OAG45412.1 - 1.3e-13 51.1 1.5 1.5e-13 51.0 0.1 1.9 2 0 0 2 2 2 1 HMG (high mobility group) box SAM_1 PF00536.30 OAG45412.1 - 1.1e-10 41.8 0.0 1.8e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) HMG_box_2 PF09011.10 OAG45412.1 - 9.2e-09 35.8 1.3 1.5e-08 35.1 0.1 2.0 2 0 0 2 2 2 1 HMG-box domain SAM_2 PF07647.17 OAG45412.1 - 9.5e-06 25.6 0.0 1.5e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) NCD1 PF04904.13 OAG45412.1 - 0.074 13.1 0.0 0.19 11.7 0.0 1.7 1 0 0 1 1 1 0 NAB conserved region 1 (NCD1) IF-2B PF01008.17 OAG45413.1 - 2.3e-73 246.8 0.4 2.7e-73 246.6 0.4 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family Methyltransf_25 PF13649.6 OAG45414.1 - 5.4e-11 43.1 0.0 9.8e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG45414.1 - 1.1e-10 42.1 0.0 2e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAG45414.1 - 0.00018 21.4 0.0 0.00025 20.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG45414.1 - 0.0034 18.1 0.0 0.0065 17.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAG45414.1 - 0.0043 16.4 0.0 0.0076 15.6 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family DREV PF05219.12 OAG45414.1 - 0.013 14.6 0.0 0.018 14.2 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_31 PF13847.6 OAG45414.1 - 0.033 14.0 0.0 0.099 12.4 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.19 OAG45414.1 - 0.068 13.3 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_4 PF02390.17 OAG45414.1 - 0.15 11.5 0.1 21 4.6 0.0 2.8 2 1 1 3 3 3 0 Putative methyltransferase RrnaAD PF00398.20 OAG45414.1 - 0.15 11.1 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase OmdA PF13376.6 OAG45417.1 - 2.7e-16 59.3 0.1 4.9e-16 58.5 0.1 1.5 1 0 0 1 1 1 1 Bacteriocin-protection, YdeI or OmpD-Associated FAD_binding_3 PF01494.19 OAG45418.1 - 1.9e-09 37.2 0.5 0.00066 19.0 0.0 2.7 3 0 0 3 3 3 2 FAD binding domain DAO PF01266.24 OAG45418.1 - 7.8e-05 22.4 0.1 0.14 11.7 0.0 2.6 2 1 1 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG45418.1 - 0.0004 19.7 0.0 0.018 14.3 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG45418.1 - 0.0016 18.6 0.0 0.0036 17.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 OAG45418.1 - 0.045 14.3 0.1 0.12 13.0 0.1 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Peptidase_S9 PF00326.21 OAG45418.1 - 0.051 13.0 0.1 0.15 11.5 0.0 1.7 2 0 0 2 2 2 0 Prolyl oligopeptidase family Nbas_N PF15492.6 OAG45418.1 - 0.068 12.5 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Neuroblastoma-amplified sequence, N terminal FAD_binding_2 PF00890.24 OAG45418.1 - 0.19 10.8 0.1 0.29 10.2 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Rad60-SLD PF11976.8 OAG45419.1 - 5.5e-17 61.4 0.1 4.8e-16 58.3 0.0 2.4 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 OAG45419.1 - 5.5e-08 32.5 0.0 3.3e-06 26.8 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin family Ribosomal_L36e PF01158.18 OAG45420.1 - 8.3e-29 99.7 3.5 3.2e-25 88.2 1.4 2.1 2 0 0 2 2 2 2 Ribosomal protein L36e MRP-L28 PF09812.9 OAG45420.1 - 0.17 12.0 1.6 0.24 11.5 0.8 1.7 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L28 M20_dimer PF07687.14 OAG45421.1 - 2.1e-14 53.3 0.0 3.4e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 OAG45421.1 - 5.9e-13 49.0 0.0 1.2e-11 44.7 0.0 2.2 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.17 OAG45421.1 - 0.0087 15.8 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 UCH PF00443.29 OAG45422.1 - 1.5e-22 80.3 0.0 2.6e-22 79.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 OAG45422.1 - 1.5e-12 47.6 0.3 2.7e-12 46.8 0.3 1.3 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein ATP-grasp_5 PF13549.6 OAG45422.1 - 0.14 11.6 0.0 4.7 6.6 0.0 2.4 2 1 0 2 2 2 0 ATP-grasp domain Cpn60_TCP1 PF00118.24 OAG45424.1 - 2.2e-143 478.5 7.9 2.5e-143 478.3 7.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family CRM1_repeat PF18777.1 OAG45424.1 - 0.096 12.2 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Chromosome region maintenance or exportin repeat Pkinase PF00069.25 OAG45425.1 - 8.3e-37 127.0 0.0 9.5e-35 120.2 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Ribonuc_2-5A PF06479.12 OAG45425.1 - 6.1e-31 107.2 0.0 1.9e-30 105.7 0.0 1.8 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase_Tyr PF07714.17 OAG45425.1 - 4.7e-16 58.8 0.0 8.9e-15 54.7 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase PQQ PF01011.21 OAG45425.1 - 2.6e-05 23.9 0.1 0.0023 17.8 0.0 3.1 4 0 0 4 4 4 1 PQQ enzyme repeat APH PF01636.23 OAG45425.1 - 0.03 14.2 0.0 1.4 8.8 0.0 2.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OAG45425.1 - 0.032 13.0 0.0 0.1 11.4 0.0 1.6 2 0 0 2 2 2 0 Fungal protein kinase Kdo PF06293.14 OAG45425.1 - 0.036 13.4 0.0 0.08 12.3 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PQQ_2 PF13360.6 OAG45425.1 - 0.068 12.7 0.0 0.19 11.3 0.0 1.8 1 1 0 1 1 1 0 PQQ-like domain NAM-associated PF14303.6 OAG45425.1 - 0.67 10.7 9.9 9.9 6.9 0.0 2.7 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain FoP_duplication PF13865.6 OAG45425.1 - 7.7 7.1 10.9 19 5.9 10.9 1.6 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 zf-LYAR PF08790.11 OAG45426.1 - 6e-08 32.5 1.7 1.5e-07 31.2 1.7 1.7 1 0 0 1 1 1 1 LYAR-type C2HC zinc finger T3SS_HrpK1 PF16937.5 OAG45426.1 - 0.018 14.7 0.0 0.03 14.0 0.0 1.3 1 0 0 1 1 1 0 Type III secretion system translocator protein, HrpF HD PF01966.22 OAG45427.1 - 1.3e-10 41.5 0.3 1.9e-10 41.0 0.3 1.2 1 0 0 1 1 1 1 HD domain INSIG PF07281.12 OAG45428.1 - 1.7e-66 223.9 1.1 2.2e-66 223.5 1.1 1.2 1 0 0 1 1 1 1 Insulin-induced protein (INSIG) HMGL-like PF00682.19 OAG45429.1 - 1.6e-42 145.9 0.0 2.3e-42 145.4 0.0 1.2 1 0 0 1 1 1 1 HMGL-like ECH_1 PF00378.20 OAG45429.1 - 9.8e-42 143.0 0.0 1.6e-41 142.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAG45429.1 - 1.7e-23 83.6 0.0 2.7e-23 83.0 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase AMP-binding PF00501.28 OAG45430.1 - 4.5e-92 308.8 0.0 5.3e-92 308.6 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG45430.1 - 9.8e-12 45.7 0.0 4.2e-11 43.7 0.0 2.2 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain Carboxyl_trans PF01039.22 OAG45431.1 - 1e-115 387.3 0.0 1.3e-115 386.9 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain Fungal_trans PF04082.18 OAG45432.1 - 1.7e-20 73.2 0.7 2.8e-20 72.5 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG45432.1 - 0.00017 21.6 3.7 0.00055 20.0 3.7 1.9 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acyl-CoA_dh_1 PF00441.24 OAG45433.1 - 5.2e-29 101.4 0.8 9.7e-29 100.5 0.8 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 OAG45433.1 - 1.7e-22 79.4 0.0 2.8e-22 78.7 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 OAG45433.1 - 6.4e-22 78.3 0.0 3.5e-21 76.0 0.0 2.3 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain CPSase_L_D2 PF02786.17 OAG45434.1 - 1.8e-69 233.5 0.0 2.8e-69 232.8 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 OAG45434.1 - 5.3e-41 139.6 0.0 1.1e-40 138.6 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 OAG45434.1 - 9e-32 109.4 0.0 1.6e-31 108.6 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Dala_Dala_lig_C PF07478.13 OAG45434.1 - 4.2e-11 42.8 0.0 9.1e-11 41.7 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl PF00364.22 OAG45434.1 - 6.8e-11 41.8 3.8 2.8e-10 39.9 3.5 2.2 1 1 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp PF02222.22 OAG45434.1 - 3.7e-10 39.6 0.1 7.5e-10 38.6 0.1 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 OAG45434.1 - 2.4e-08 34.2 0.0 4.1e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 OAG45434.1 - 0.011 15.5 0.2 0.094 12.6 0.0 2.3 2 0 0 2 2 2 0 Biotin-lipoyl like ATPgrasp_YheCD PF14398.6 OAG45434.1 - 0.039 13.2 0.0 1.3 8.2 0.0 2.2 2 0 0 2 2 2 0 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 OAG45434.1 - 0.11 11.8 0.0 0.3 10.3 0.0 1.6 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp GCV_H PF01597.19 OAG45434.1 - 0.17 11.8 0.2 0.37 10.7 0.2 1.5 1 0 0 1 1 1 0 Glycine cleavage H-protein Polysacc_synt_4 PF04669.13 OAG45435.1 - 8.2e-21 74.4 0.1 1.2e-10 41.2 0.0 2.0 1 1 1 2 2 2 2 Polysaccharide biosynthesis ABC_membrane PF00664.23 OAG45436.1 - 2e-64 217.9 27.3 3.7e-46 158.0 7.6 3.1 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 OAG45436.1 - 3.3e-61 205.8 0.0 2.6e-29 102.5 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 OAG45436.1 - 1.5e-15 57.2 3.7 9.3e-05 22.0 0.0 4.5 4 0 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 OAG45436.1 - 3.7e-10 40.2 0.9 0.0072 16.6 0.0 4.4 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.6 OAG45436.1 - 4.9e-09 35.8 1.3 0.0024 17.6 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 OAG45436.1 - 1.4e-08 34.8 0.0 0.0028 17.6 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase ABC_ATPase PF09818.9 OAG45436.1 - 2.6e-08 33.1 6.7 0.0013 17.7 0.2 4.3 4 1 0 4 4 4 2 Predicted ATPase of the ABC class AAA_25 PF13481.6 OAG45436.1 - 2.6e-06 27.2 3.7 1.1 8.8 0.1 3.6 3 0 0 3 3 3 3 AAA domain AAA_16 PF13191.6 OAG45436.1 - 4e-06 27.3 1.6 0.013 15.8 0.0 3.2 2 1 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 OAG45436.1 - 1.8e-05 24.7 1.7 3.1 7.5 0.1 4.4 5 0 0 5 5 5 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 OAG45436.1 - 7.4e-05 22.6 1.5 0.037 13.7 0.1 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 OAG45436.1 - 9.9e-05 22.9 2.2 0.24 11.9 0.1 2.4 2 0 0 2 2 2 2 AAA domain CobA_CobO_BtuR PF02572.15 OAG45436.1 - 0.00021 21.6 1.0 0.056 13.7 0.5 2.6 2 0 0 2 2 2 1 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP DEAD PF00270.29 OAG45436.1 - 0.00025 20.9 0.9 2.2 8.0 0.0 3.7 3 1 0 3 3 3 2 DEAD/DEAH box helicase MMR_HSR1 PF01926.23 OAG45436.1 - 0.00038 20.5 0.1 0.3 11.2 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase SbcCD_C PF13558.6 OAG45436.1 - 0.0013 18.9 0.6 0.79 10.0 0.0 3.0 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.6 OAG45436.1 - 0.0027 17.9 0.0 1.4 9.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 OAG45436.1 - 0.0029 18.2 0.0 1.4 9.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 OAG45436.1 - 0.0029 17.2 0.1 2.8 7.4 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region cobW PF02492.19 OAG45436.1 - 0.0033 17.0 2.9 0.5 9.9 0.0 3.9 4 0 0 4 4 4 1 CobW/HypB/UreG, nucleotide-binding domain ATP-synt_ab PF00006.25 OAG45436.1 - 0.0053 16.4 1.4 2.8 7.5 0.0 3.2 3 1 0 3 3 3 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_24 PF13479.6 OAG45436.1 - 0.0087 15.8 0.8 1.7 8.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 OAG45436.1 - 0.01 15.9 9.1 0.65 10.0 0.1 3.0 3 0 0 3 3 2 0 Helicase HerA, central domain DUF3987 PF13148.6 OAG45436.1 - 0.011 14.8 0.1 2.3 7.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) Zeta_toxin PF06414.12 OAG45436.1 - 0.011 15.0 0.0 1.7 7.9 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin RNA_helicase PF00910.22 OAG45436.1 - 0.015 15.7 0.2 2 8.8 0.0 2.8 2 0 0 2 2 2 0 RNA helicase FtsK_SpoIIIE PF01580.18 OAG45436.1 - 0.028 13.8 2.0 7.2 5.9 0.0 3.0 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_5 PF07728.14 OAG45436.1 - 0.03 14.3 0.4 8.5 6.4 0.0 3.3 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 OAG45436.1 - 0.067 12.6 0.3 1.6 8.0 0.0 2.7 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI G-alpha PF00503.20 OAG45436.1 - 0.09 11.9 0.0 4.9 6.2 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit ATPase PF06745.13 OAG45436.1 - 0.11 11.8 7.4 3.2 7.0 0.0 3.4 3 0 0 3 3 3 0 KaiC T2SSE PF00437.20 OAG45436.1 - 0.15 11.1 2.4 7 5.6 0.0 3.1 3 0 0 3 3 3 0 Type II/IV secretion system protein Guanylate_kin PF00625.21 OAG45436.1 - 0.21 11.2 0.1 14 5.3 0.0 2.5 2 0 0 2 2 2 0 Guanylate kinase AAA_10 PF12846.7 OAG45436.1 - 0.21 10.5 0.3 7.4 5.4 0.0 2.8 3 0 0 3 3 3 0 AAA-like domain APS_kinase PF01583.20 OAG45436.1 - 0.64 9.9 3.3 5.1 7.0 0.1 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase CbiA PF01656.23 OAG45436.1 - 1.1 9.3 4.8 9.7 6.3 0.1 3.0 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain NACHT PF05729.12 OAG45436.1 - 3.4 7.6 6.6 5.3 6.9 0.2 3.3 3 0 0 3 3 3 0 NACHT domain AAA_28 PF13521.6 OAG45436.1 - 7.6 6.8 5.8 68 3.7 0.0 3.4 3 0 0 3 3 3 0 AAA domain DUF3328 PF11807.8 OAG45437.1 - 7.5e-21 74.9 0.0 9.9e-21 74.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Pro_isomerase PF00160.21 OAG45438.1 - 9.8e-51 172.2 0.1 2.1e-50 171.1 0.1 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 OAG45438.1 - 2.3e-08 34.6 0.1 0.0023 18.7 0.0 4.2 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAG45438.1 - 0.013 15.8 0.0 4.3 7.7 0.0 3.1 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Cytokin_check_N PF10407.9 OAG45439.1 - 0.03 14.3 0.1 0.064 13.2 0.1 1.5 1 0 0 1 1 1 0 Cdc14 phosphatase binding protein N-terminus eIF2_C PF09173.11 OAG45440.1 - 4.6e-34 116.5 0.3 1.1e-33 115.4 0.3 1.7 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 OAG45440.1 - 8.4e-23 80.9 0.2 6.1e-22 78.1 0.2 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 OAG45440.1 - 1.4e-11 44.6 0.6 3.1e-11 43.5 0.6 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RsgA_GTPase PF03193.16 OAG45440.1 - 0.0029 17.5 0.1 0.031 14.2 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 OAG45440.1 - 0.0049 16.9 0.0 0.0097 16.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 OAG45440.1 - 0.14 12.2 0.0 0.52 10.4 0.0 2.0 3 0 0 3 3 3 0 Dynamin family MMR_HSR1_Xtn PF16897.5 OAG45440.1 - 0.15 12.1 0.1 0.3 11.1 0.1 1.5 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain FTA2 PF13095.6 OAG45441.1 - 3.4e-14 53.0 0.0 4.2e-14 52.7 0.0 1.1 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 DUF2625 PF10946.8 OAG45441.1 - 0.077 12.1 0.0 0.1 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF2625 DBP10CT PF08147.12 OAG45441.1 - 0.16 12.2 0.0 0.26 11.6 0.0 1.4 1 0 0 1 1 1 0 DBP10CT (NUC160) domain MRP-L27 PF09809.9 OAG45442.1 - 1.1e-08 34.9 0.0 2.8e-08 33.6 0.0 1.7 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 TFIIA PF03153.13 OAG45442.1 - 0.061 13.3 19.2 0.072 13.1 19.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3864 PF12980.7 OAG45442.1 - 0.12 12.7 0.3 0.34 11.3 0.2 1.8 1 1 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3864) SLC12 PF03522.15 OAG45442.1 - 7.1 5.5 12.3 8.9 5.2 12.3 1.2 1 0 0 1 1 1 0 Solute carrier family 12 Complex1_LYR PF05347.15 OAG45443.1 - 3.9e-05 23.6 0.1 0.00016 21.6 0.0 2.1 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Glyco_hydro81C PF17652.1 OAG45444.1 - 1.2e-162 541.0 6.8 1.6e-162 540.7 6.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 OAG45444.1 - 1.9e-109 365.7 0.1 1.9e-109 365.7 0.1 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 81 N-terminal domain Utp14 PF04615.13 OAG45445.1 - 6.2e-186 620.3 50.9 6.2e-186 620.3 50.9 2.5 1 1 1 2 2 2 1 Utp14 protein APH PF01636.23 OAG45446.1 - 2.6e-12 47.2 0.0 4.2e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 OAG45446.1 - 0.0017 18.0 0.0 0.0026 17.4 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.20 OAG45446.1 - 0.031 13.6 0.0 0.056 12.7 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase RIO1 PF01163.22 OAG45446.1 - 0.033 13.8 0.0 0.062 12.9 0.0 1.4 1 0 0 1 1 1 0 RIO1 family DUF1679 PF07914.11 OAG45446.1 - 0.29 9.9 0.0 0.41 9.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Ank_2 PF12796.7 OAG45448.1 - 3.9e-13 49.8 0.3 1.5e-05 25.5 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAG45448.1 - 1.2e-12 48.1 1.3 1.3e-07 32.0 0.1 4.8 3 2 2 5 5 5 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 OAG45448.1 - 1.9e-11 44.0 0.1 0.00011 22.5 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAG45448.1 - 5.6e-09 35.5 0.1 0.035 14.6 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 OAG45448.1 - 0.00017 21.9 0.8 1 9.9 0.0 4.2 4 0 0 4 4 4 1 Ankyrin repeat KilA-N PF04383.13 OAG45448.1 - 0.0012 18.6 0.3 0.016 15.1 0.3 2.3 1 1 0 1 1 1 1 KilA-N domain JAKMIP_CC3 PF16034.5 OAG45448.1 - 0.098 12.6 10.6 0.013 15.4 5.3 2.1 2 0 0 2 2 2 0 JAKMIP CC3 domain Sec8_exocyst PF04048.14 OAG45448.1 - 0.21 11.5 4.7 0.071 13.0 1.7 1.7 2 0 0 2 2 1 0 Sec8 exocyst complex component specific domain CREPT PF16566.5 OAG45448.1 - 0.86 9.8 8.4 0.062 13.5 3.0 1.9 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour COX16 PF14138.6 OAG45448.1 - 1.6 9.3 5.2 0.86 10.2 0.1 2.5 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein COX16 Spc7 PF08317.11 OAG45448.1 - 1.9 7.3 14.7 0.55 9.1 9.6 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein Serine_rich PF08824.10 OAG45448.1 - 2.6 8.1 5.4 23 4.9 0.3 2.8 2 1 1 3 3 3 0 Serine rich protein interaction domain UPF0242 PF06785.11 OAG45448.1 - 5.1 7.1 8.5 1.3 9.1 4.8 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF349 PF03993.12 OAG45448.1 - 5.4 7.4 8.2 13 6.1 7.8 2.0 1 1 0 1 1 1 0 Domain of Unknown Function (DUF349) PIN_8 PF18476.1 OAG45448.1 - 7.4 6.4 7.9 2.7 7.8 3.1 2.2 2 0 0 2 2 2 0 PIN like domain ZapB PF06005.12 OAG45448.1 - 7.8 7.0 16.5 10 6.7 6.4 3.5 2 1 1 3 3 3 0 Cell division protein ZapB TPR_1 PF00515.28 OAG45450.1 - 2e-07 30.5 0.2 0.94 9.4 0.0 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 OAG45450.1 - 0.00011 22.3 0.1 0.005 17.1 0.0 3.7 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 OAG45450.1 - 0.00034 20.5 11.8 0.12 12.5 0.0 5.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 OAG45450.1 - 0.0039 17.1 3.9 1.4 9.2 0.1 4.0 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 OAG45450.1 - 0.015 15.0 0.0 1.4 8.6 0.0 2.9 2 1 1 3 3 3 0 TPR repeat TPR_10 PF13374.6 OAG45450.1 - 0.1 12.5 2.6 4.1 7.4 0.2 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 OAG45450.1 - 1.9 9.2 23.6 0.2 12.3 0.3 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 OAG45450.1 - 5.5 7.4 14.5 0.31 11.4 0.5 5.2 4 1 1 5 5 5 0 Tetratricopeptide repeat PLDc_2 PF13091.6 OAG45451.1 - 7.6e-18 64.7 0.1 4.2e-07 29.9 0.0 3.7 3 1 0 3 3 3 3 PLD-like domain PLDc PF00614.22 OAG45451.1 - 4.9e-14 51.8 3.4 7.8e-08 32.2 0.3 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif NAD_binding_7 PF13241.6 OAG45452.1 - 6.3e-28 97.3 0.0 9.8e-28 96.7 0.0 1.3 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 OAG45452.1 - 4.2e-26 90.4 0.2 6.4e-26 89.8 0.2 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 OAG45452.1 - 2.1e-14 52.6 0.3 3.9e-14 51.8 0.3 1.5 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Pyr_redox_3 PF13738.6 OAG45452.1 - 0.00057 19.2 0.0 0.00088 18.6 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 OAG45452.1 - 0.034 14.2 0.1 0.072 13.1 0.1 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase LSDAT_prok PF18171.1 OAG45452.1 - 0.082 12.1 0.0 0.26 10.5 0.1 1.7 2 0 0 2 2 2 0 SLOG in TRPM, prokaryote Pribosyltran_N PF13793.6 OAG45453.1 - 1.2e-41 141.3 0.0 4.1e-41 139.6 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 OAG45453.1 - 1.5e-29 103.3 0.1 2.2e-24 86.5 0.0 2.2 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 OAG45453.1 - 6.8e-06 25.7 0.0 0.0035 16.9 0.0 2.5 2 0 0 2 2 2 2 Phosphoribosyl transferase domain NAD_binding_4 PF07993.12 OAG45453.1 - 0.11 11.6 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein Serinc PF03348.15 OAG45454.1 - 5.3e-157 523.2 11.2 6e-157 523.0 11.2 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) MFS_1 PF07690.16 OAG45455.1 - 4.4e-16 58.7 33.4 1.5e-14 53.7 32.6 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.13 OAG45455.1 - 3.3e-08 33.3 2.2 3.3e-08 33.3 2.2 1.9 2 0 0 2 2 2 1 Nodulin-like Tmemb_170 PF10190.9 OAG45455.1 - 0.91 9.9 6.2 2.3 8.6 3.6 3.1 3 1 0 3 3 3 0 Putative transmembrane protein 170 DUF1772 PF08592.11 OAG45455.1 - 1.8 8.9 11.5 1.1 9.5 1.0 3.4 3 1 1 4 4 4 0 Domain of unknown function (DUF1772) Shugoshin_N PF07558.11 OAG45456.1 - 0.00028 20.7 2.2 0.00048 19.9 1.1 1.9 2 0 0 2 2 2 1 Shugoshin N-terminal coiled-coil region Atg14 PF10186.9 OAG45456.1 - 0.00065 18.9 0.8 0.008 15.3 0.2 2.0 2 0 0 2 2 2 1 Vacuolar sorting 38 and autophagy-related subunit 14 TMCO5 PF14992.6 OAG45456.1 - 0.011 15.3 0.2 0.029 14.0 0.0 1.6 2 0 0 2 2 2 0 TMCO5 family SlyX PF04102.12 OAG45456.1 - 0.021 15.4 5.5 2.4 8.8 0.1 2.4 2 0 0 2 2 2 0 SlyX bZIP_1 PF00170.21 OAG45456.1 - 0.046 13.8 0.2 0.046 13.8 0.2 1.6 2 0 0 2 2 2 0 bZIP transcription factor Cnn_1N PF07989.11 OAG45456.1 - 0.062 13.5 1.6 0.37 11.0 0.0 2.4 2 1 0 2 2 2 0 Centrosomin N-terminal motif 1 Baculo_PEP_C PF04513.12 OAG45456.1 - 0.067 13.2 3.6 0.086 12.9 0.2 2.0 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DivIC PF04977.15 OAG45456.1 - 0.075 12.8 0.2 0.075 12.8 0.2 2.4 2 0 0 2 2 2 0 Septum formation initiator MerR-DNA-bind PF09278.11 OAG45456.1 - 0.1 13.1 6.4 0.26 11.8 0.2 2.4 2 0 0 2 2 2 0 MerR, DNA binding GreA_GreB_N PF03449.15 OAG45456.1 - 0.13 12.5 2.7 0.28 11.4 0.1 2.2 2 0 0 2 2 2 0 Transcription elongation factor, N-terminal ATG16 PF08614.11 OAG45456.1 - 0.21 11.8 8.4 0.21 11.8 0.3 2.5 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) Jnk-SapK_ap_N PF09744.9 OAG45456.1 - 0.35 11.1 5.7 0.35 11.1 0.1 2.1 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Siah-Interact_N PF09032.11 OAG45456.1 - 5.4 7.4 7.1 0.42 11.0 0.4 2.3 2 1 0 2 2 2 0 Siah interacting protein, N terminal CEND1 PF15677.5 OAG45457.1 - 0.037 14.6 5.5 0.06 13.9 5.5 1.3 1 0 0 1 1 1 0 Cell cycle exit and neuronal differentiation protein 1 Rho_N PF07498.12 OAG45457.1 - 0.046 13.7 0.1 0.12 12.4 0.1 1.7 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain DUF1421 PF07223.11 OAG45458.1 - 1.5 8.8 3.7 0.72 9.7 0.2 2.3 3 0 0 3 3 3 0 UBA-like domain (DUF1421) Methyltransf_10 PF05971.12 OAG45459.1 - 1.5e-51 175.5 0.1 2.4e-50 171.6 0.1 2.0 1 1 0 1 1 1 1 RNA methyltransferase MTS PF05175.14 OAG45459.1 - 0.066 12.8 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain PAPA-1 PF04795.12 OAG45459.1 - 0.084 13.7 2.2 0.21 12.4 2.2 1.6 1 0 0 1 1 1 0 PAPA-1-like conserved region NOA36 PF06524.12 OAG45459.1 - 5.5 6.2 7.0 8.2 5.6 7.0 1.1 1 0 0 1 1 1 0 NOA36 protein Sec7 PF01369.20 OAG45460.1 - 2.5e-72 242.4 0.5 9.8e-72 240.5 0.5 2.2 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 OAG45460.1 - 1.8e-42 144.9 4.2 1.8e-42 144.9 4.2 3.0 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 OAG45460.1 - 4.7e-33 112.9 12.3 5.4e-33 112.7 0.1 5.7 7 0 0 7 7 7 1 Domain of unknown function (DUF1981) DCB PF16213.5 OAG45460.1 - 4.9e-17 62.1 5.9 9.8e-17 61.2 0.9 3.1 3 0 0 3 3 3 1 Dimerisation and cyclophilin-binding domain of Mon2 2-oxoacid_dh PF00198.23 OAG45461.1 - 3.4e-75 252.5 0.1 4.2e-75 252.2 0.1 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 OAG45461.1 - 1.2e-14 53.8 1.3 3.5e-14 52.4 1.3 1.9 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 OAG45461.1 - 5.9e-14 52.1 1.0 1.7e-13 50.6 1.0 1.9 1 0 0 1 1 1 1 e3 binding domain Mito_carr PF00153.27 OAG45462.1 - 6.3e-63 208.7 1.4 9.6e-21 73.5 0.4 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein Septin PF00735.18 OAG45463.1 - 9.3e-121 402.4 0.1 9.3e-121 402.4 0.1 1.8 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 OAG45463.1 - 1.5e-08 34.7 0.5 4.3e-08 33.2 0.0 2.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OAG45463.1 - 2.5e-05 23.9 2.6 0.0013 18.3 0.0 3.0 2 2 0 2 2 2 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 OAG45463.1 - 0.00026 21.5 4.7 0.023 15.2 0.0 2.7 2 1 0 2 2 2 1 ABC transporter AAA_16 PF13191.6 OAG45463.1 - 0.0013 19.1 0.2 0.0053 17.1 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain Roc PF08477.13 OAG45463.1 - 0.0025 18.0 0.0 0.0061 16.8 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 OAG45463.1 - 0.0026 17.7 0.7 0.0026 17.7 0.7 3.6 3 1 0 3 3 3 1 RsgA GTPase AIG1 PF04548.16 OAG45463.1 - 0.0027 17.1 2.1 0.0042 16.4 0.0 2.2 2 0 0 2 2 2 1 AIG1 family Ras PF00071.22 OAG45463.1 - 0.0083 15.7 0.0 0.046 13.3 0.0 2.3 2 1 0 2 2 2 1 Ras family AAA_22 PF13401.6 OAG45463.1 - 0.0093 16.2 1.8 0.024 14.9 0.0 2.6 2 2 1 3 3 3 1 AAA domain AAA_29 PF13555.6 OAG45463.1 - 0.018 14.8 0.0 0.034 13.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 OAG45463.1 - 0.024 15.2 6.9 6.6 7.2 6.7 2.2 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 OAG45463.1 - 0.053 13.6 9.3 0.95 9.5 0.0 3.6 3 1 0 3 3 3 0 Dynamin family AAA_24 PF13479.6 OAG45463.1 - 0.055 13.2 0.0 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 OAG45463.1 - 0.069 13.5 0.7 0.8 10.1 0.0 2.6 2 0 0 2 2 2 0 RNA helicase Flu_M1 PF00598.19 OAG45463.1 - 0.071 12.6 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Influenza Matrix protein (M1) ATP_bind_1 PF03029.17 OAG45463.1 - 0.089 12.6 3.0 3 7.6 0.0 3.1 3 1 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_7 PF12775.7 OAG45463.1 - 0.11 12.1 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Caldesmon PF02029.15 OAG45463.1 - 0.17 10.6 16.6 0.35 9.6 16.6 1.5 1 0 0 1 1 1 0 Caldesmon DUF2937 PF11157.8 OAG45463.1 - 0.2 11.3 5.0 0.54 10.0 5.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) Exonuc_VII_L PF02601.15 OAG45463.1 - 0.39 10.3 9.1 0.72 9.4 9.1 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF87 PF01935.17 OAG45463.1 - 0.52 10.4 4.4 4.8 7.2 0.0 2.6 2 0 0 2 2 2 0 Helicase HerA, central domain DUF3987 PF13148.6 OAG45463.1 - 1.8 7.5 0.0 1.8 7.5 0.0 2.5 2 1 0 2 2 1 0 Protein of unknown function (DUF3987) UPF0242 PF06785.11 OAG45463.1 - 3.1 7.9 16.5 5.7 7.0 16.5 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus MnmE_helical PF12631.7 OAG45463.1 - 3.5 7.7 7.0 9.7 6.3 7.0 1.6 1 0 0 1 1 1 0 MnmE helical domain Atg14 PF10186.9 OAG45463.1 - 9.6 5.2 10.2 15 4.6 10.2 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 UPF0121 PF03661.13 OAG45464.1 - 2.7e-32 112.1 6.0 3.6e-32 111.7 6.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) MOZ_SAS PF01853.18 OAG45465.1 - 2.8e-70 235.6 0.0 4.5e-70 235.0 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 OAG45465.1 - 2.1e-16 59.3 3.8 3.7e-16 58.5 3.8 1.4 1 0 0 1 1 1 1 MYST family zinc finger domain PHD_4 PF16866.5 OAG45465.1 - 9e-06 25.7 7.5 4.2e-05 23.5 6.8 2.6 1 1 1 2 2 2 1 PHD-finger PHD PF00628.29 OAG45465.1 - 3.8e-05 23.5 7.1 3.8e-05 23.5 7.1 2.0 2 0 0 2 2 2 1 PHD-finger Prok-RING_1 PF14446.6 OAG45465.1 - 0.019 14.9 3.1 0.055 13.4 3.1 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zf-RING_9 PF13901.6 OAG45465.1 - 0.032 14.2 3.6 0.064 13.2 3.6 1.4 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon C1_1 PF00130.22 OAG45465.1 - 0.24 11.3 6.2 0.042 13.8 2.2 1.8 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.6 OAG45465.1 - 7.9 6.1 6.8 2.8 7.6 3.6 1.9 2 0 0 2 2 2 0 PHD-finger RraA-like PF03737.15 OAG45466.1 - 5.2e-30 104.6 0.0 7.5e-30 104.1 0.0 1.3 1 0 0 1 1 1 1 Aldolase/RraA Vma12 PF11712.8 OAG45467.1 - 4.8 7.2 5.5 8.7 6.4 5.5 1.4 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Pro_CA PF00484.19 OAG45468.1 - 1.7e-44 151.8 0.0 2.1e-44 151.5 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase FAD_binding_3 PF01494.19 OAG45469.1 - 6.9e-17 61.7 2.9 8.6e-15 54.8 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 OAG45469.1 - 2.1e-08 34.1 8.4 0.00013 21.7 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_oxidored PF12831.7 OAG45469.1 - 6.3e-08 32.4 0.2 1.1e-07 31.6 0.2 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG45469.1 - 6.2e-07 28.9 2.0 0.00082 18.7 0.5 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAG45469.1 - 6.6e-06 26.6 2.1 0.015 15.8 0.5 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG45469.1 - 1.7e-05 25.0 1.6 3.8e-05 23.8 1.6 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 OAG45469.1 - 7.2e-05 21.8 2.9 0.023 13.6 0.9 2.9 3 0 0 3 3 3 2 Tryptophan halogenase Amino_oxidase PF01593.24 OAG45469.1 - 0.00019 20.8 2.1 0.14 11.4 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase GIDA PF01134.22 OAG45469.1 - 0.00033 19.8 1.3 0.00049 19.3 1.3 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 OAG45469.1 - 0.0017 17.5 8.0 0.0017 17.5 8.0 2.3 2 1 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 OAG45469.1 - 0.0048 15.7 5.8 0.013 14.3 4.3 1.9 2 0 0 2 2 2 1 HI0933-like protein DUF3603 PF12227.8 OAG45469.1 - 0.012 15.0 0.0 0.019 14.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3603) Thi4 PF01946.17 OAG45469.1 - 0.018 14.3 0.7 0.037 13.3 0.7 1.5 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 OAG45469.1 - 0.07 12.4 0.7 1.4 8.1 0.8 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 OAG45469.1 - 0.11 12.4 1.4 0.19 11.6 1.4 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SE PF08491.10 OAG45469.1 - 0.22 10.6 0.0 0.63 9.0 0.0 1.7 1 1 0 1 1 1 0 Squalene epoxidase AlaDh_PNT_C PF01262.21 OAG45469.1 - 1.6 8.0 5.6 0.27 10.5 1.6 1.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Fungal_trans PF04082.18 OAG45470.1 - 1.7e-34 119.0 0.2 2.6e-34 118.5 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG45470.1 - 1.3e-07 31.6 5.9 2.6e-07 30.7 5.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_25 PF13649.6 OAG45471.1 - 4.6e-16 59.3 0.0 8.3e-16 58.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG45471.1 - 5.7e-14 52.2 0.0 7.6e-14 51.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAG45471.1 - 3.2e-13 49.8 0.0 4.5e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG45471.1 - 6e-12 46.1 0.0 1e-11 45.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG45471.1 - 2.9e-10 40.8 0.0 5.6e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 OAG45471.1 - 5.7e-05 22.5 0.0 8.7e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain FtsJ PF01728.19 OAG45471.1 - 0.00014 22.0 0.0 0.00037 20.6 0.0 1.6 2 0 0 2 2 2 1 FtsJ-like methyltransferase MTS PF05175.14 OAG45471.1 - 0.00023 20.7 0.0 0.00036 20.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 OAG45471.1 - 0.00025 21.1 0.0 0.00038 20.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 OAG45471.1 - 0.00068 19.5 0.0 0.0012 18.6 0.0 1.4 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.17 OAG45471.1 - 0.0035 16.8 0.0 0.0077 15.7 0.0 1.5 2 0 0 2 2 2 1 Putative methyltransferase TehB PF03848.14 OAG45471.1 - 0.015 14.7 0.0 0.026 14.0 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_5 PF01795.19 OAG45471.1 - 0.02 14.4 0.0 0.06 12.8 0.0 1.7 2 0 0 2 2 2 0 MraW methylase family RrnaAD PF00398.20 OAG45471.1 - 0.096 11.7 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Ubie_methyltran PF01209.18 OAG45471.1 - 0.11 11.8 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_33 PF10017.9 OAG45471.1 - 0.11 11.6 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent CMAS PF02353.20 OAG45471.1 - 0.11 11.7 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Stealth_CR3 PF17102.5 OAG45471.1 - 0.14 12.1 0.5 0.46 10.4 0.1 2.1 2 0 0 2 2 2 0 Stealth protein CR3, conserved region 3 Tannase PF07519.11 OAG45474.1 - 1.3e-99 334.3 0.0 1.5e-99 334.1 0.0 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase DJ-1_PfpI PF01965.24 OAG45475.1 - 9.3e-11 41.8 0.0 1.1e-10 41.5 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family DUF2689 PF10894.8 OAG45475.1 - 0.14 12.0 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2689) DIT1_PvcA PF05141.12 OAG45476.1 - 4.5e-88 295.3 0.0 6.3e-88 294.8 0.0 1.2 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein ABC_tran PF00005.27 OAG45476.1 - 1.4e-09 38.6 0.0 3.8e-09 37.2 0.0 1.7 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 OAG45476.1 - 0.00051 20.0 0.0 0.0012 18.8 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_25 PF13481.6 OAG45476.1 - 0.0025 17.4 0.2 0.0068 16.0 0.1 1.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OAG45476.1 - 0.041 14.3 0.4 0.3 11.5 0.3 2.5 2 1 0 2 2 2 0 AAA ATPase domain AMP-binding PF00501.28 OAG45477.1 - 4.8e-24 84.7 0.0 8.2e-24 84.0 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Transferase PF02458.15 OAG45477.1 - 4.4e-09 35.5 0.0 4.4e-06 25.6 0.0 2.3 2 0 0 2 2 2 2 Transferase family PP-binding PF00550.25 OAG45477.1 - 3.4e-07 30.5 0.0 8.5e-07 29.2 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site CRAL_TRIO_2 PF13716.6 OAG45477.1 - 0.067 13.4 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain MFS_1 PF07690.16 OAG45478.1 - 8.7e-40 136.7 46.5 1.2e-38 132.9 46.3 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 OAG45478.1 - 1.5e-10 40.2 14.1 3.4e-10 39.0 14.1 1.8 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAG45479.1 - 4.8e-20 71.8 50.2 7.1e-17 61.4 50.2 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 OAG45479.1 - 1.4e-06 27.1 26.6 1.9e-06 26.6 26.6 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Parathyroid PF01279.17 OAG45480.1 - 0.12 13.0 0.1 0.23 12.1 0.1 1.5 1 0 0 1 1 1 0 Parathyroid hormone family HET PF06985.11 OAG45481.1 - 1.9e-35 122.3 1.0 3.9e-35 121.3 1.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) POB3_N PF17292.2 OAG45482.1 - 4.1e-30 104.1 0.0 9e-29 99.8 0.0 2.7 3 0 0 3 3 3 1 POB3-like N-terminal PH domain SSrecog PF03531.14 OAG45482.1 - 4.9e-30 103.2 0.0 5.3e-29 99.9 0.0 2.7 2 0 0 2 2 2 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.12 OAG45482.1 - 1.3e-25 89.6 0.0 1.7e-24 86.1 0.0 2.6 3 0 0 3 3 3 1 Histone chaperone Rttp106-like PH_TFIIH PF08567.11 OAG45482.1 - 0.022 15.1 0.0 0.69 10.3 0.0 3.1 4 0 0 4 4 4 0 TFIIH p62 subunit, N-terminal domain Zn_clus PF00172.18 OAG45483.1 - 6.7e-08 32.5 11.5 1e-07 31.9 11.5 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Neur_chan_memb PF02932.16 OAG45483.1 - 6.1 6.8 5.9 0.4 10.7 0.6 1.6 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region PH PF00169.29 OAG45484.1 - 3e-06 27.7 0.0 9.5e-05 22.9 0.0 3.1 3 0 0 3 3 3 1 PH domain PH_9 PF15410.6 OAG45484.1 - 0.0019 18.6 0.0 0.0086 16.4 0.0 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain Sec7 PF01369.20 OAG45485.1 - 5.1e-31 107.8 0.0 8.1e-31 107.1 0.0 1.2 1 0 0 1 1 1 1 Sec7 domain PH PF00169.29 OAG45485.1 - 6.5e-08 33.0 0.8 2.5e-07 31.2 0.8 2.1 1 1 0 1 1 1 1 PH domain PH_9 PF15410.6 OAG45485.1 - 7.8e-07 29.5 0.1 2.2e-06 28.1 0.1 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain p450 PF00067.22 OAG45486.1 - 5.9e-74 249.5 0.0 7.8e-74 249.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.25 OAG45487.1 - 1.7e-15 57.0 0.0 3.2e-14 52.9 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG45487.1 - 3e-08 33.5 0.0 4.9e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG45487.1 - 0.00065 19.7 0.0 0.00095 19.1 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG45487.1 - 0.16 11.4 0.1 0.45 9.9 0.1 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Rhodanese PF00581.20 OAG45488.1 - 7.5e-10 39.3 0.0 9.8e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain zf-RRN7 PF11781.8 OAG45489.1 - 6.3e-06 25.8 3.5 1.3e-05 24.7 3.5 1.6 1 0 0 1 1 1 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 eIF-5a PF01287.20 OAG45490.1 - 4.7e-29 100.3 1.2 6.6e-29 99.8 1.2 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 OAG45490.1 - 0.00028 20.9 0.2 0.01 15.9 0.0 2.4 2 0 0 2 2 2 1 Elongation factor P (EF-P) KOW-like domain p450 PF00067.22 OAG45491.1 - 1e-53 182.7 0.0 1.2e-53 182.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_23 PF13489.6 OAG45492.1 - 3.1e-21 75.9 0.0 5.2e-21 75.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG45492.1 - 4.3e-10 40.2 0.0 1e-09 39.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG45492.1 - 8.1e-09 36.1 0.0 3.7e-08 34.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG45492.1 - 8.9e-08 32.1 0.0 1.1e-06 28.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG45492.1 - 2.2e-06 28.2 0.0 4.8e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OAG45492.1 - 0.00069 19.2 0.0 0.0026 17.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_4 PF02390.17 OAG45492.1 - 0.0028 17.1 0.0 0.03 13.8 0.0 2.2 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_16 PF10294.9 OAG45492.1 - 0.011 15.4 0.0 0.018 14.8 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase PrmA PF06325.13 OAG45492.1 - 0.012 15.0 0.0 0.023 14.1 0.0 1.4 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF938 PF06080.12 OAG45492.1 - 0.021 14.6 0.0 0.033 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) DSBA PF01323.20 OAG45493.1 - 7.4e-46 156.4 0.0 4e-23 82.2 0.0 2.8 2 1 0 2 2 2 2 DSBA-like thioredoxin domain Lactamase_B PF00753.27 OAG45493.1 - 7.1e-10 39.2 0.1 1.5e-09 38.2 0.1 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Thioredoxin_5 PF13743.6 OAG45493.1 - 0.052 13.2 0.0 0.17 11.5 0.0 1.7 2 0 0 2 2 2 0 Thioredoxin Lactamase_B_2 PF12706.7 OAG45493.1 - 0.09 12.3 0.0 0.49 9.9 0.0 2.1 2 0 0 2 2 2 0 Beta-lactamase superfamily domain Fungal_trans PF04082.18 OAG45494.1 - 2.2e-29 102.3 0.1 4.2e-29 101.4 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain SnoaL_4 PF13577.6 OAG45495.1 - 3e-09 37.1 0.5 8.1e-09 35.7 0.5 1.7 1 1 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 OAG45495.1 - 0.003 18.0 0.5 0.0046 17.3 0.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_2 PF12680.7 OAG45495.1 - 0.038 14.6 1.3 0.066 13.9 1.3 1.4 1 0 0 1 1 1 0 SnoaL-like domain p450 PF00067.22 OAG45496.1 - 4.5e-67 226.8 0.0 5.5e-67 226.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 OAG45497.1 - 6.7e-28 97.6 38.4 6.7e-28 97.6 38.4 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily FAD_binding_3 PF01494.19 OAG45498.1 - 1.9e-20 73.4 0.1 6.4e-20 71.7 0.1 1.7 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 OAG45498.1 - 1.8e-06 27.4 0.5 0.00045 19.5 0.1 1.9 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OAG45498.1 - 7.2e-05 22.0 4.9 0.00018 20.7 3.5 2.1 2 1 0 2 2 2 1 Lycopene cyclase protein Amino_oxidase PF01593.24 OAG45498.1 - 0.00048 19.6 0.4 0.24 10.6 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 OAG45498.1 - 0.00052 20.5 0.1 0.001 19.6 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAG45498.1 - 0.0038 17.4 2.9 0.0097 16.1 2.9 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 OAG45498.1 - 0.0053 16.0 1.4 0.014 14.6 0.6 1.8 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 OAG45498.1 - 0.0058 16.3 9.3 0.41 10.2 6.9 2.3 1 1 1 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OAG45498.1 - 0.0069 15.5 5.1 0.011 14.9 5.1 1.3 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.14 OAG45498.1 - 0.008 15.1 1.8 0.091 11.6 0.4 2.3 1 1 0 2 2 2 1 Tryptophan halogenase Pyr_redox_3 PF13738.6 OAG45498.1 - 0.034 13.4 0.8 0.071 12.4 0.8 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAG45498.1 - 0.042 12.6 3.6 0.068 11.9 3.6 1.3 1 0 0 1 1 1 0 HI0933-like protein SE PF08491.10 OAG45498.1 - 0.067 12.2 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase GDI PF00996.18 OAG45498.1 - 0.11 11.0 0.0 0.15 10.6 0.0 1.1 1 0 0 1 1 1 0 GDP dissociation inhibitor NAD_Gly3P_dh_N PF01210.23 OAG45498.1 - 0.15 12.1 0.1 0.27 11.2 0.1 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus AlaDh_PNT_C PF01262.21 OAG45498.1 - 0.46 9.7 2.9 0.36 10.1 1.1 1.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 OAG45498.1 - 1.6 7.7 4.4 2.8 6.9 4.5 1.5 1 1 0 1 1 1 0 Glucose inhibited division protein A Aldedh PF00171.22 OAG45499.1 - 1.9e-130 435.5 1.4 2.2e-130 435.3 1.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 OAG45499.1 - 0.029 13.4 0.0 0.049 12.7 0.0 1.4 1 1 0 1 1 1 0 Acyl-CoA reductase (LuxC) ADH_N PF08240.12 OAG45500.1 - 6.9e-23 80.6 1.9 6.9e-23 80.6 1.9 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAG45500.1 - 1.6e-22 79.9 2.3 3.3e-22 78.9 2.3 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAG45500.1 - 2.1e-06 28.8 0.0 4.9e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 OAG45500.1 - 2.6e-06 27.1 1.8 4e-06 26.5 1.8 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 OAG45500.1 - 0.008 15.5 5.6 0.018 14.3 5.5 1.7 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NADH_4Fe-4S PF10589.9 OAG45500.1 - 0.05 13.7 2.1 0.15 12.2 1.3 2.1 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region Vps52 PF04129.12 OAG45501.1 - 6.1e-123 411.2 0.0 8.1e-123 410.8 0.0 1.0 1 0 0 1 1 1 1 Vps52 / Sac2 family Sec3_C PF09763.9 OAG45501.1 - 0.00031 19.3 2.7 0.00048 18.7 2.7 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec3 Cluap1 PF10234.9 OAG45501.1 - 0.0092 15.4 0.3 0.019 14.4 0.3 1.5 1 0 0 1 1 1 1 Clusterin-associated protein-1 Mer2 PF09074.10 OAG45501.1 - 0.017 14.9 1.6 0.36 10.6 0.4 2.4 2 0 0 2 2 2 0 Mer2 TBCC_N PF16752.5 OAG45501.1 - 0.025 15.0 0.5 0.025 15.0 0.5 2.6 2 0 0 2 2 2 0 Tubulin-specific chaperone C N-terminal domain Baculo_PEP_C PF04513.12 OAG45501.1 - 0.15 12.1 0.1 0.15 12.1 0.1 2.4 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Rab5-bind PF09311.11 OAG45501.1 - 0.51 9.7 6.2 3.7 6.9 0.3 2.8 3 0 0 3 3 3 0 Rabaptin-like protein THOC7 PF05615.13 OAG45501.1 - 0.53 10.6 6.6 0.067 13.5 1.5 2.0 2 0 0 2 2 2 0 Tho complex subunit 7 Sec8_exocyst PF04048.14 OAG45501.1 - 1.3 8.9 3.8 1.7 8.5 0.7 2.3 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain BST2 PF16716.5 OAG45501.1 - 3.6 8.2 7.1 0.5 11.0 1.7 2.2 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 APG6_N PF17675.1 OAG45501.1 - 7.4 7.1 8.1 4.8 7.7 0.9 2.6 3 0 0 3 3 3 0 Apg6 coiled-coil region Pkinase PF00069.25 OAG45502.1 - 2.5e-19 69.7 0.0 3.3e-19 69.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG45502.1 - 3.7e-13 49.4 0.0 1.6e-12 47.3 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAG45502.1 - 0.00014 21.3 0.0 0.00019 20.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 OAG45502.1 - 0.0022 18.0 0.5 0.011 15.7 0.4 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 OAG45502.1 - 0.0052 16.2 0.0 0.0079 15.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OAG45502.1 - 0.0076 15.9 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 1 RIO1 family AA_permease PF00324.21 OAG45504.1 - 3.1e-124 415.2 34.6 3.5e-124 415.0 34.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAG45504.1 - 2.3e-32 112.4 37.9 3.1e-32 112.0 37.9 1.1 1 0 0 1 1 1 1 Amino acid permease DUF4635 PF15466.6 OAG45505.1 - 0.055 13.0 0.0 0.099 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4635) Hamartin PF04388.12 OAG45505.1 - 5.4 5.5 10.6 6.7 5.2 10.6 1.1 1 0 0 1 1 1 0 Hamartin protein Afi1 PF07792.12 OAG45506.1 - 1.7e-41 141.8 0.2 1.7e-41 141.8 0.2 1.7 2 0 0 2 2 2 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.10 OAG45506.1 - 4.6e-38 129.7 0.0 1.2e-37 128.4 0.0 1.7 2 0 0 2 2 2 1 Stabilization of polarity axis Avl9 PF09794.9 OAG45506.1 - 3.3e-07 29.3 0.0 0.039 12.6 0.0 3.9 2 2 1 3 3 3 3 Transport protein Avl9 DUF2347 PF09804.9 OAG45506.1 - 0.019 14.6 0.0 0.065 12.8 0.0 1.9 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) TFIIF_alpha PF05793.12 OAG45506.1 - 0.093 11.3 11.7 0.0095 14.6 2.8 2.1 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) EF-hand_6 PF13405.6 OAG45507.1 - 7.6e-09 34.8 0.0 0.00087 19.0 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 OAG45507.1 - 1.3e-07 30.6 0.0 0.0016 17.9 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 OAG45507.1 - 4.1e-06 26.0 0.4 0.0055 16.1 0.1 2.4 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 OAG45507.1 - 1.9e-05 25.0 0.2 0.00076 19.9 0.0 2.3 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 OAG45507.1 - 0.049 13.5 0.1 1.3 9.0 0.1 2.6 2 1 1 3 3 3 0 EF-hand domain pair UPF0114 PF03350.16 OAG45508.1 - 0.017 15.3 0.7 1.9 8.7 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized protein family, UPF0114 DUF4448 PF14610.6 OAG45509.1 - 0.00026 20.8 0.0 0.00043 20.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) TMEM154 PF15102.6 OAG45509.1 - 0.00053 19.9 0.9 0.00053 19.9 0.9 2.0 1 1 1 2 2 2 1 TMEM154 protein family SKG6 PF08693.10 OAG45509.1 - 0.00055 19.3 0.3 0.0013 18.1 0.3 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain RIFIN PF02009.16 OAG45509.1 - 0.015 15.2 0.5 0.023 14.6 0.5 1.1 1 0 0 1 1 1 0 Rifin DUF4083 PF13314.6 OAG45509.1 - 0.23 11.4 0.4 0.56 10.2 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) Stevor PF17410.2 OAG45509.1 - 0.63 9.5 1.6 0.89 9.0 1.6 1.1 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame SnoaL_4 PF13577.6 OAG45510.1 - 2.9e-17 63.0 1.3 3.8e-17 62.6 1.3 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_2 PF12680.7 OAG45510.1 - 5.8e-05 23.7 0.7 0.00029 21.4 0.2 1.9 1 1 1 2 2 2 1 SnoaL-like domain Peptidase_S9_N PF02897.15 OAG45510.1 - 0.016 14.1 0.0 0.023 13.5 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase, N-terminal beta-propeller domain DUF4440 PF14534.6 OAG45510.1 - 0.018 15.5 0.1 0.033 14.6 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4440) Fungal_trans PF04082.18 OAG45511.1 - 4.9e-08 32.3 0.0 8.5e-08 31.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG45511.1 - 6.8e-07 29.3 9.4 1.2e-06 28.5 9.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HIPIP PF01355.17 OAG45511.1 - 5.3 7.5 9.0 18 5.8 2.3 2.6 2 0 0 2 2 2 0 High potential iron-sulfur protein Sugar_tr PF00083.24 OAG45512.1 - 8.6e-81 272.1 26.1 2.9e-75 253.9 17.9 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 OAG45512.1 - 2.4e-09 36.6 34.2 2.4e-09 36.6 34.2 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily SnoaL_4 PF13577.6 OAG45513.1 - 2.9e-13 50.1 1.4 3.5e-13 49.8 1.4 1.1 1 0 0 1 1 1 1 SnoaL-like domain Vps8 PF12816.7 OAG45514.1 - 1.4e-54 184.6 0.3 3.7e-54 183.3 0.1 1.8 2 0 0 2 2 2 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.20 OAG45514.1 - 3e-07 30.4 0.4 0.0021 17.9 0.0 2.6 2 0 0 2 2 2 2 Region in Clathrin and VPS Glyco_hydro_16 PF00722.21 OAG45514.1 - 1.2e-05 24.8 0.0 2.7e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 zf-C3H2C3 PF17122.5 OAG45514.1 - 4.8e-05 23.3 0.1 0.00011 22.2 0.1 1.5 1 0 0 1 1 1 1 Zinc-finger zf-RING_11 PF17123.5 OAG45514.1 - 0.13 12.0 0.2 0.31 10.8 0.2 1.6 1 0 0 1 1 1 0 RING-like zinc finger Peroxin-13_N PF04088.13 OAG45515.1 - 8.3e-49 165.6 0.1 1.2e-48 165.0 0.1 1.3 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.17 OAG45515.1 - 4.2e-09 35.9 0.0 7.1e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 OAG45515.1 - 6.3e-09 35.3 0.0 1.1e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 OAG45515.1 - 0.00016 21.4 0.0 0.00029 20.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain hSH3 PF14603.6 OAG45515.1 - 0.046 14.2 0.0 0.084 13.3 0.0 1.3 1 0 0 1 1 1 0 Helically-extended SH3 domain RRM_1 PF00076.22 OAG45516.1 - 1.8e-15 56.5 0.0 9.3e-13 47.8 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_pol_3_Rpc31 PF11705.8 OAG45516.1 - 0.061 13.6 10.6 0.14 12.4 10.6 1.6 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 NOA36 PF06524.12 OAG45516.1 - 0.073 12.4 7.1 0.12 11.7 7.1 1.4 1 0 0 1 1 1 0 NOA36 protein CNDH2_M PF16869.5 OAG45516.1 - 0.11 13.2 12.6 0.28 11.9 12.6 1.7 1 0 0 1 1 1 0 PF16858 TFIIA PF03153.13 OAG45516.1 - 0.16 11.9 14.2 0.25 11.3 14.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nop14 PF04147.12 OAG45516.1 - 1.5 6.9 11.1 2.2 6.4 11.1 1.2 1 0 0 1 1 1 0 Nop14-like family PPP4R2 PF09184.11 OAG45516.1 - 7.2 6.1 14.1 11 5.5 14.1 1.2 1 0 0 1 1 1 0 PPP4R2 TRAP_alpha PF03896.16 OAG45516.1 - 9.8 5.3 6.5 14 4.8 6.5 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Glucosamine_iso PF01182.20 OAG45517.1 - 1.1e-67 228.2 0.0 1.3e-67 228.0 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Abhydrolase_1 PF00561.20 OAG45518.1 - 2.5e-19 69.9 0.1 8.9e-17 61.6 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAG45518.1 - 3.2e-15 57.4 8.5 1.4e-14 55.2 8.5 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG45518.1 - 0.012 14.9 0.0 0.84 8.9 0.0 2.1 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 OAG45518.1 - 0.082 11.8 0.0 0.15 10.9 0.0 1.4 1 1 0 1 1 1 0 Chlorophyllase enzyme Pkinase PF00069.25 OAG45519.1 - 1e-36 126.7 0.0 1.5e-36 126.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG45519.1 - 1e-13 51.2 0.0 1.9e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAG45519.1 - 3.1e-05 22.9 0.1 6.4e-05 21.9 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 OAG45519.1 - 0.0053 16.7 0.0 0.015 15.2 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 OAG45519.1 - 0.019 14.6 0.0 0.033 13.8 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 OAG45519.1 - 0.036 13.4 0.0 0.057 12.7 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 OAG45519.1 - 0.078 12.3 0.1 0.14 11.5 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Trimer_CC PF08954.11 OAG45520.1 - 0.028 13.9 0.1 0.063 12.8 0.1 1.5 1 0 0 1 1 1 0 Trimerisation motif FA PF08736.11 OAG45520.1 - 0.57 10.3 0.2 0.57 10.3 0.2 2.7 3 0 0 3 3 3 0 FERM adjacent (FA) Putative_PNPOx PF01243.20 OAG45521.1 - 0.03 14.5 0.0 0.85 9.9 0.0 2.3 2 0 0 2 2 2 0 Pyridoxamine 5'-phosphate oxidase Amino_oxidase PF01593.24 OAG45522.1 - 1.5e-87 294.8 0.0 1.6e-85 288.1 0.0 2.2 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase SWIRM PF04433.17 OAG45522.1 - 3.9e-13 49.5 0.0 8.3e-13 48.5 0.0 1.6 1 0 0 1 1 1 1 SWIRM domain NAD_binding_8 PF13450.6 OAG45522.1 - 1.6e-08 34.6 0.0 5.6e-08 32.9 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HMG_box PF00505.19 OAG45522.1 - 1.7e-07 31.5 3.3 2.3e-06 27.9 3.3 2.4 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 OAG45522.1 - 4.2e-06 27.3 4.3 1.1e-05 25.9 4.3 1.8 1 0 0 1 1 1 1 HMG-box domain NAD_binding_9 PF13454.6 OAG45522.1 - 9.8e-06 25.6 0.5 0.017 15.1 0.0 3.3 3 1 0 3 3 3 2 FAD-NAD(P)-binding DAO PF01266.24 OAG45522.1 - 2.1e-05 24.3 0.0 5.9e-05 22.8 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAG45522.1 - 0.00012 21.5 0.0 0.038 13.2 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OAG45522.1 - 0.0036 16.4 0.0 1.5 7.8 0.0 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein HI0933_like PF03486.14 OAG45522.1 - 0.29 9.8 1.7 7.8 5.1 0.0 3.1 3 0 0 3 3 3 0 HI0933-like protein NAD_binding_1 PF00175.21 OAG45523.1 - 2.8e-06 27.9 0.0 1.4e-05 25.7 0.0 2.0 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 OAG45523.1 - 0.00019 21.6 0.1 0.057 13.5 0.1 2.1 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Metallophos PF00149.28 OAG45524.1 - 3.5e-16 60.3 0.8 3.5e-16 60.3 0.8 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OAG45524.1 - 3.5e-05 24.1 0.1 0.00039 20.7 0.1 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain GCD14 PF08704.10 OAG45525.1 - 2e-06 27.7 0.0 0.0019 17.9 0.0 2.2 2 0 0 2 2 2 2 tRNA methyltransferase complex GCD14 subunit GCD14_N PF14801.6 OAG45525.1 - 0.0069 16.2 0.0 0.017 15.0 0.0 1.7 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit N-term Ribosomal_S30 PF04758.14 OAG45525.1 - 0.053 13.7 0.1 0.11 12.6 0.1 1.5 1 0 0 1 1 1 0 Ribosomal protein S30 Methyltransf_24 PF13578.6 OAG45525.1 - 0.15 13.1 0.2 0.63 11.1 0.1 2.1 2 1 0 2 2 2 0 Methyltransferase domain Mito_carr PF00153.27 OAG45526.1 - 1.3e-55 185.3 0.4 6e-21 74.2 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Peptidase_C2 PF00648.21 OAG45527.1 - 9.8e-28 97.0 0.0 1.5e-27 96.4 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 OAG45527.1 - 1.6e-10 41.4 0.0 7.5e-09 36.0 0.0 3.0 2 1 0 2 2 2 1 Calpain large subunit, domain III DUF4164 PF13747.6 OAG45527.1 - 0.13 12.5 1.2 0.25 11.7 1.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) FAD_binding_3 PF01494.19 OAG45528.1 - 1.1e-19 70.9 0.9 1.3e-16 60.8 0.0 3.3 2 1 0 2 2 2 2 FAD binding domain SE PF08491.10 OAG45528.1 - 0.00011 21.4 0.0 0.00016 20.8 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase Lycopene_cycl PF05834.12 OAG45528.1 - 0.0077 15.3 1.2 1.7 7.6 0.1 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein Flavin_Reduct PF01613.18 OAG45529.1 - 1.5e-24 86.8 0.0 1.8e-24 86.6 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain adh_short PF00106.25 OAG45531.1 - 3.9e-27 95.0 0.0 1.3e-22 80.2 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAG45531.1 - 4.3e-11 42.8 0.0 6.8e-10 38.9 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG45531.1 - 7.8e-09 35.7 0.0 1.3e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 KR domain Flavin_Reduct PF01613.18 OAG45534.1 - 6.8e-13 48.9 0.0 1.3e-12 48.0 0.0 1.4 1 0 0 1 1 1 1 Flavin reductase like domain ATP_bind_2 PF03668.15 OAG45534.1 - 8.2e-06 25.3 0.0 1.4e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 P-loop ATPase protein family Pirin PF02678.16 OAG45535.1 - 6.2e-30 103.4 0.2 1.3e-29 102.3 0.2 1.6 2 0 0 2 2 2 1 Pirin Pirin_C PF05726.13 OAG45535.1 - 1.5e-26 92.7 0.0 1.9e-25 89.2 0.0 2.2 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.11 OAG45535.1 - 3.4e-07 29.9 1.9 9.5e-05 22.0 0.8 2.5 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 OAG45535.1 - 0.15 11.8 2.9 1.4 8.6 0.0 3.1 3 1 1 4 4 4 0 Protein of unknown function (DUF861) eIF-3_zeta PF05091.12 OAG45536.1 - 3.9e-206 686.1 0.0 4.7e-206 685.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF2530 PF10745.9 OAG45536.1 - 0.27 11.5 3.6 0.59 10.4 3.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2530) Frag1 PF10277.9 OAG45537.1 - 5.5e-11 42.4 14.5 8.6e-11 41.8 14.5 1.2 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF2079 PF09852.9 OAG45537.1 - 0.00045 19.2 8.0 0.00067 18.6 8.0 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2079) NmrA PF05368.13 OAG45538.1 - 1.3e-16 60.9 0.0 1.7e-12 47.4 0.0 2.1 2 0 0 2 2 2 2 NmrA-like family NAD_binding_10 PF13460.6 OAG45538.1 - 8.5e-08 32.3 0.0 3.4e-07 30.3 0.0 2.0 1 1 0 1 1 1 1 NAD(P)H-binding SUIM_assoc PF16619.5 OAG45538.1 - 0.031 14.3 4.0 0.084 13.0 4.0 1.7 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 MAGE PF01454.19 OAG45538.1 - 0.043 13.5 0.6 0.14 11.8 0.5 1.7 2 0 0 2 2 2 0 MAGE family bZIP_1 PF00170.21 OAG45539.1 - 0.0004 20.4 5.6 0.0011 19.1 5.6 1.6 1 0 0 1 1 1 1 bZIP transcription factor GvpL_GvpF PF06386.11 OAG45539.1 - 1.1 9.1 4.7 2.1 8.2 4.7 1.4 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF HLH PF00010.26 OAG45541.1 - 0.00035 20.5 0.7 0.00073 19.5 0.7 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain SPO22 PF08631.10 OAG45542.1 - 8.8e-27 94.3 11.8 3.3e-25 89.1 10.0 3.9 3 1 0 3 3 3 1 Meiosis protein SPO22/ZIP4 like BTB PF00651.31 OAG45543.1 - 1.8e-06 28.2 0.0 1e-05 25.7 0.0 2.0 1 1 0 1 1 1 1 BTB/POZ domain Sulfatase PF00884.23 OAG45544.1 - 7.8e-57 193.0 0.0 9.7e-57 192.7 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Choline_sulf_C PF12411.8 OAG45544.1 - 2.5e-26 91.3 4.9 5.4e-25 86.9 2.3 2.5 1 1 1 2 2 2 2 Choline sulfatase enzyme C terminal Phosphodiest PF01663.22 OAG45544.1 - 6.6e-09 35.8 0.0 3.3e-08 33.5 0.0 1.9 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.6 OAG45544.1 - 0.00065 20.4 0.3 0.0026 18.5 0.1 2.0 1 1 1 2 2 2 1 C-terminal region of aryl-sulfatase DUF229 PF02995.17 OAG45544.1 - 0.015 13.9 0.0 0.023 13.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) DUF4994 PF16385.5 OAG45544.1 - 0.017 15.1 0.1 0.51 10.3 0.0 2.4 1 1 1 2 2 2 0 Domain of unknown function DUF4976 PF16347.5 OAG45544.1 - 0.073 13.3 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4976) PMT PF02366.18 OAG45545.1 - 3.5e-84 282.2 17.8 6.1e-84 281.4 17.8 1.4 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 OAG45545.1 - 2.2e-68 229.8 5.2 2.2e-68 229.8 5.2 3.4 2 1 2 4 4 4 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 OAG45545.1 - 4.4e-17 62.5 0.0 1.1e-16 61.2 0.0 1.6 1 1 0 1 1 1 1 MIR domain PMT_2 PF13231.6 OAG45545.1 - 0.00011 22.5 9.2 0.00011 22.5 9.2 3.7 5 1 0 5 5 5 1 Dolichyl-phosphate-mannose-protein mannosyltransferase DUF1206 PF06724.11 OAG45545.1 - 1.5 8.9 6.1 0.33 11.0 0.1 2.9 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1206) Caps_synth_CapC PF14102.6 OAG45545.1 - 2.4 8.6 8.0 0.17 12.3 1.0 2.7 3 1 0 3 3 3 0 Capsule biosynthesis CapC DUF2723 PF11028.8 OAG45545.1 - 2.5 8.0 7.5 3.1 7.7 3.1 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2723) HTH_26 PF13443.6 OAG45546.1 - 0.045 14.2 0.1 0.093 13.2 0.1 1.5 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain MFS_1 PF07690.16 OAG45547.1 - 6.7e-32 110.8 24.7 6.7e-32 110.8 24.7 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG45547.1 - 0.35 9.7 25.3 1.4 7.6 25.3 2.1 1 1 0 1 1 1 0 Sugar (and other) transporter Saf_2TM PF18303.1 OAG45547.1 - 3.5 7.2 6.5 11 5.6 0.4 3.4 3 0 0 3 3 3 0 SAVED-fused 2TM effector domain CENP-Q PF13094.6 OAG45548.1 - 2e-31 109.4 8.0 3.8e-31 108.5 8.0 1.5 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit LIN37 PF15306.6 OAG45548.1 - 0.037 14.3 1.6 0.095 12.9 1.6 1.7 1 0 0 1 1 1 0 LIN37 AAA_23 PF13476.6 OAG45548.1 - 0.059 13.9 0.1 0.09 13.3 0.1 1.3 1 0 0 1 1 1 0 AAA domain CorA PF01544.18 OAG45549.1 - 1e-12 48.0 0.2 6.8e-11 42.0 0.4 2.3 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein DUF2207 PF09972.9 OAG45549.1 - 0.27 10.0 0.6 0.42 9.3 0.6 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Macoilin PF09726.9 OAG45550.1 - 5.8 5.3 13.0 8.5 4.8 13.0 1.2 1 0 0 1 1 1 0 Macoilin family LLC1 PF14945.6 OAG45550.1 - 6.5 7.4 8.8 0.28 11.8 0.4 2.6 2 1 1 3 3 3 0 Normal lung function maintenance, Low in Lung Cancer 1 protein Abhydrolase_1 PF00561.20 OAG45551.1 - 0.062 12.9 0.0 0.18 11.5 0.1 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold PH PF00169.29 OAG45552.1 - 0.00013 22.4 0.0 0.00028 21.4 0.0 1.6 1 0 0 1 1 1 1 PH domain Prominin PF05478.11 OAG45552.1 - 0.0034 15.4 0.5 0.0047 15.0 0.5 1.1 1 0 0 1 1 1 1 Prominin Med9 PF07544.13 OAG45552.1 - 0.074 13.1 0.3 2.3 8.4 0.8 2.8 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Tim17 PF02466.19 OAG45553.1 - 2.8e-05 24.5 7.8 8.4e-05 22.9 7.5 1.9 1 1 1 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family RPT PF13446.6 OAG45554.1 - 1.3e-45 153.2 1.2 3.2e-13 49.4 0.1 4.6 4 0 0 4 4 4 4 A repeated domain in UCH-protein UCH PF00443.29 OAG45554.1 - 6.4e-40 137.3 0.0 2.5e-39 135.3 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase PUB PF09409.10 OAG45554.1 - 8.1e-06 25.7 0.0 2.2e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 PUB domain UCH_1 PF13423.6 OAG45554.1 - 2.4e-05 24.1 0.3 0.00071 19.3 0.1 2.7 3 0 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase zf-CCHC PF00098.23 OAG45555.1 - 0.016 15.2 1.4 0.016 15.2 1.4 5.2 5 0 0 5 5 5 0 Zinc knuckle HJURP_mid PF12346.8 OAG45555.1 - 0.16 12.4 2.8 0.51 10.8 0.0 2.8 2 1 1 3 3 3 0 Holliday junction recognition protein-associated repeat Nop14 PF04147.12 OAG45555.1 - 1.3 7.2 10.1 1.8 6.7 10.1 1.2 1 0 0 1 1 1 0 Nop14-like family zf-CCHC_4 PF14392.6 OAG45555.1 - 2.4 7.9 23.5 0.81 9.5 0.2 4.6 4 1 1 5 5 5 0 Zinc knuckle GEN1_C PF18380.1 OAG45555.1 - 3.1 8.7 7.5 9.2 7.2 2.4 3.5 4 0 0 4 4 4 0 Holliday junction resolvase Gen1 C-terminal domain Tub_N PF16322.5 OAG45555.1 - 5.1 7.5 12.8 17 5.7 12.8 1.9 1 1 0 1 1 1 0 Tubby N-terminal SDA1 PF05285.12 OAG45555.1 - 6 6.2 10.9 12 5.2 10.9 1.4 1 0 0 1 1 1 0 SDA1 DEAD PF00270.29 OAG45556.1 - 1.3e-18 67.4 0.0 2.7e-18 66.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 OAG45556.1 - 2.4e-11 43.9 0.0 6.5e-11 42.5 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 OAG45556.1 - 8.4e-07 29.3 0.0 2.9e-06 27.6 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PhoH PF02562.16 OAG45556.1 - 0.086 12.3 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein zf-CCCH PF00642.24 OAG45557.1 - 1.4e-07 31.2 1.1 2.8e-07 30.3 1.1 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 OAG45557.1 - 4e-06 26.7 2.9 7.9e-06 25.7 2.9 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 OAG45557.1 - 0.0081 15.9 1.1 0.014 15.2 1.1 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger Torus PF16131.5 OAG45557.1 - 0.13 13.0 0.9 0.25 12.0 0.1 1.9 2 0 0 2 2 2 0 Torus domain ORMDL PF04061.14 OAG45558.1 - 5.7e-59 197.8 4.8 6.8e-59 197.5 4.8 1.1 1 0 0 1 1 1 1 ORMDL family Glycophorin_A PF01102.18 OAG45560.1 - 0.0065 16.7 0.2 0.011 16.0 0.2 1.5 1 1 0 1 1 1 1 Glycophorin A TMEM51 PF15345.6 OAG45560.1 - 0.012 15.4 0.1 0.014 15.3 0.1 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 Herpes_gE PF02480.16 OAG45560.1 - 0.035 12.9 0.1 0.041 12.6 0.1 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Adeno_E3_CR2 PF02439.15 OAG45560.1 - 0.044 13.5 0.3 0.072 12.9 0.3 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 LST1 PF05083.13 OAG45560.1 - 0.073 13.4 0.1 0.13 12.5 0.1 1.4 1 0 0 1 1 1 0 LST-1 protein RGS PF00615.19 OAG45561.1 - 2.8e-05 24.4 0.0 0.046 14.0 0.0 2.4 2 0 0 2 2 2 2 Regulator of G protein signaling domain ABM PF03992.16 OAG45562.1 - 3.7e-05 23.8 0.2 5.8e-05 23.1 0.2 1.3 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase SMC_N PF02463.19 OAG45563.1 - 2.7e-21 76.0 0.0 4.8e-21 75.2 0.0 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 OAG45563.1 - 1.5e-13 51.7 13.6 1.5e-13 51.7 13.6 4.5 2 2 1 3 3 3 1 AAA domain AAA_15 PF13175.6 OAG45563.1 - 5.4e-06 26.4 1.2 0.00028 20.7 0.0 2.9 2 2 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 OAG45563.1 - 0.00039 20.3 0.5 0.025 14.4 0.0 3.1 3 1 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 OAG45563.1 - 0.00076 19.2 0.0 0.0017 18.0 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Snapin_Pallidin PF14712.6 OAG45563.1 - 0.0046 17.3 1.9 0.0046 17.3 1.9 5.6 4 1 1 5 5 5 2 Snapin/Pallidin AAA PF00004.29 OAG45563.1 - 0.026 14.9 0.2 0.61 10.5 0.0 2.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AMP-binding PF00501.28 OAG45564.1 - 3e-78 263.3 0.0 3.7e-78 263.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAG45564.1 - 6.1e-15 56.0 0.1 1.3e-14 55.0 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Fungal_trans_2 PF11951.8 OAG45565.1 - 5.2e-12 45.3 0.2 2.4e-11 43.1 0.0 1.9 1 1 0 2 2 2 1 Fungal specific transcription factor domain XPB_DRD PF18458.1 OAG45565.1 - 0.002 18.0 0.0 0.0044 16.9 0.0 1.5 1 0 0 1 1 1 1 Xeroderma pigmentosum group B helicase damage recognition domain DASH_Dam1 PF08653.10 OAG45565.1 - 0.39 10.6 1.8 17 5.3 0.1 3.2 4 0 0 4 4 4 0 DASH complex subunit Dam1 Nuc_sug_transp PF04142.15 OAG45566.1 - 5.2e-111 370.8 28.1 1.6e-109 365.9 28.1 2.0 1 1 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 OAG45566.1 - 2.9e-07 30.7 29.2 0.00023 21.4 4.5 2.2 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 OAG45566.1 - 3.2e-07 29.9 18.3 7.3e-07 28.7 16.2 2.1 2 0 0 2 2 2 1 UAA transporter family PUNUT PF16913.5 OAG45566.1 - 0.0008 18.7 20.9 0.0022 17.3 20.9 1.7 1 1 0 1 1 1 1 Purine nucleobase transmembrane transport EmrE PF13536.6 OAG45566.1 - 0.002 17.8 16.5 0.0035 17.0 15.5 1.7 1 1 1 2 2 2 1 Putative multidrug resistance efflux transporter LCCL PF03815.19 OAG45567.1 - 4.3e-19 68.4 0.0 7.3e-19 67.7 0.0 1.3 1 0 0 1 1 1 1 LCCL domain DsbB PF02600.16 OAG45567.1 - 0.011 16.1 6.9 0.026 15.0 0.0 2.7 3 0 0 3 3 3 0 Disulfide bond formation protein DsbB RTA1 PF04479.13 OAG45568.1 - 3.8e-71 239.0 10.1 3.8e-71 239.0 10.1 2.0 1 1 1 2 2 2 2 RTA1 like protein NAD_binding_6 PF08030.12 OAG45569.1 - 1.6e-33 116.1 0.0 3.4e-33 115.0 0.0 1.6 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 OAG45569.1 - 6.9e-21 74.4 0.0 1.6e-20 73.2 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 OAG45569.1 - 7.5e-19 68.1 14.3 7.9e-19 68.0 10.5 2.3 1 1 1 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.21 OAG45569.1 - 0.082 13.6 0.0 0.44 11.2 0.0 2.3 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 OAG45569.1 - 0.097 13.0 0.0 0.22 11.9 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain UQ_con PF00179.26 OAG45570.1 - 2e-50 170.1 0.0 2.1e-50 170.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OAG45570.1 - 0.0081 15.9 0.0 0.01 15.5 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 OAG45570.1 - 0.046 14.0 0.0 0.066 13.5 0.0 1.2 1 0 0 1 1 1 0 RWD domain UEV PF05743.13 OAG45570.1 - 0.051 13.4 0.0 0.08 12.8 0.0 1.3 1 0 0 1 1 1 0 UEV domain Acyl-CoA_dh_N PF02771.16 OAG45571.1 - 4.7e-26 91.7 0.2 1.1e-25 90.5 0.2 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 OAG45571.1 - 5.6e-25 88.3 0.2 9.4e-25 87.6 0.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 OAG45571.1 - 3.5e-17 62.4 0.0 6.3e-17 61.6 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 OAG45571.1 - 3.3e-06 27.4 0.3 7.4e-06 26.3 0.3 1.6 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain XPG_I PF00867.18 OAG45572.1 - 5.8e-32 109.9 2.0 1.2e-31 108.9 0.0 2.3 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.17 OAG45572.1 - 1.4e-25 89.7 0.0 5.2e-25 87.9 0.0 2.0 1 0 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc PF01367.20 OAG45572.1 - 3.4e-05 24.3 1.8 0.00012 22.6 0.0 2.5 2 1 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold HHH_5 PF14520.6 OAG45572.1 - 0.042 14.5 0.0 0.1 13.2 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix domain HXXSHH PF07586.11 OAG45572.1 - 0.71 9.4 7.5 0.49 9.9 5.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1552) Linker_histone PF00538.19 OAG45573.1 - 3.6e-25 88.1 6.6 2.1e-24 85.7 2.2 3.0 2 1 0 2 2 2 1 linker histone H1 and H5 family p450 PF00067.22 OAG45574.1 - 7.1e-52 176.7 0.0 8.8e-52 176.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3107 PF11305.8 OAG45574.1 - 0.14 12.4 0.0 37 4.7 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3107) Cpn60_TCP1 PF00118.24 OAG45575.1 - 2.4e-150 501.4 11.8 2.7e-150 501.2 11.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family AAA PF00004.29 OAG45576.1 - 6e-41 140.0 0.0 1.1e-40 139.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OAG45576.1 - 1.2e-06 28.2 0.1 3.5e-06 26.7 0.0 1.8 2 0 0 2 2 1 1 AAA+ lid domain AAA_22 PF13401.6 OAG45576.1 - 6.6e-05 23.2 0.0 0.0059 16.9 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 OAG45576.1 - 0.00011 22.2 0.0 0.00043 20.3 0.0 2.2 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 OAG45576.1 - 0.00014 22.0 0.0 0.00069 19.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 OAG45576.1 - 0.00044 20.7 0.1 0.012 16.1 0.0 2.4 1 1 0 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 OAG45576.1 - 0.0015 17.8 0.0 0.0025 17.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 OAG45576.1 - 0.008 15.9 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 OAG45576.1 - 0.016 15.5 0.1 0.063 13.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 OAG45576.1 - 0.027 14.0 0.0 0.087 12.3 0.0 1.9 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 OAG45576.1 - 0.047 13.9 0.0 0.094 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 OAG45576.1 - 0.052 13.9 0.0 0.16 12.4 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 OAG45576.1 - 0.068 12.9 0.1 0.24 11.1 0.0 2.1 2 1 0 2 2 2 0 AAA domain AAA_11 PF13086.6 OAG45576.1 - 0.079 12.7 0.6 0.5 10.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.11 OAG45576.1 - 0.088 12.7 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 OAG45576.1 - 0.098 12.4 0.3 0.59 9.8 0.0 2.3 3 0 0 3 3 3 0 AAA domain DUF4168 PF13767.6 OAG45576.1 - 0.1 13.8 1.9 0.45 11.7 2.1 1.9 2 0 0 2 2 1 0 Domain of unknown function (DUF4168) Antigen_Bd37 PF11641.8 OAG45576.1 - 0.1 12.0 0.2 0.21 11.1 0.2 1.4 1 0 0 1 1 1 0 Glycosylphosphatidylinositol-anchored merozoite surface protein Mg_chelatase PF01078.21 OAG45576.1 - 0.12 11.7 0.1 0.35 10.2 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 OAG45576.1 - 0.15 12.6 0.0 0.49 10.9 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_14 PF13173.6 OAG45576.1 - 0.15 12.1 0.0 0.33 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain FAD_binding_2 PF00890.24 OAG45577.1 - 1.4e-124 416.4 2.1 1.8e-124 416.1 2.1 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 OAG45577.1 - 1.7e-45 154.1 0.7 2.5e-45 153.6 0.7 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 OAG45577.1 - 1.1e-05 24.9 0.7 0.00085 18.6 0.0 3.1 4 0 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OAG45577.1 - 3.9e-05 22.9 1.9 0.024 13.7 2.2 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.17 OAG45577.1 - 6.8e-05 22.2 0.3 0.032 13.5 0.1 2.3 2 0 0 2 2 2 2 Thi4 family FAD_binding_3 PF01494.19 OAG45577.1 - 0.0033 16.7 0.6 0.0068 15.7 0.1 1.8 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 OAG45577.1 - 0.047 13.3 1.9 0.12 11.9 1.9 1.8 1 1 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 OAG45577.1 - 0.15 10.8 1.3 0.37 9.5 0.3 2.1 3 0 0 3 3 3 0 HI0933-like protein CAP PF00188.26 OAG45579.1 - 0.00051 20.9 0.3 0.00051 20.9 0.3 2.8 2 2 0 2 2 2 1 Cysteine-rich secretory protein family zf-H2C2_5 PF13909.6 OAG45580.1 - 0.0011 18.6 4.8 0.0011 18.6 4.8 2.5 2 0 0 2 2 2 1 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 OAG45580.1 - 0.025 15.0 2.2 0.025 15.0 2.2 3.2 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-met PF12874.7 OAG45580.1 - 1.6 9.3 7.8 24 5.5 3.1 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 OAG45580.1 - 4.2 8.0 18.7 0.46 11.0 2.9 3.0 3 0 0 3 3 3 0 Zinc-finger double domain Peptidase_M22 PF00814.25 OAG45581.1 - 3.4e-48 164.7 0.0 7.6e-47 160.3 0.0 2.6 1 1 0 1 1 1 1 Glycoprotease family Cornifin PF02389.15 OAG45582.1 - 0.0018 18.5 7.0 0.0036 17.5 6.9 1.5 1 1 0 1 1 1 1 Cornifin (SPRR) family YjfB_motility PF14070.6 OAG45582.1 - 0.12 12.5 0.0 15 5.9 0.0 2.4 2 0 0 2 2 2 0 Putative motility protein AA_permease_2 PF13520.6 OAG45583.1 - 7.5e-53 179.9 47.0 9.9e-53 179.5 47.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAG45583.1 - 2.2e-18 66.1 40.2 3e-18 65.7 40.2 1.1 1 0 0 1 1 1 1 Amino acid permease PufQ PF05398.11 OAG45583.1 - 0.012 15.8 1.0 0.065 13.4 0.1 2.6 2 1 0 2 2 2 0 PufQ cytochrome subunit DUF1254 PF06863.12 OAG45584.1 - 5.6e-28 97.6 2.5 6.1e-28 97.5 0.9 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1254) DUF1214 PF06742.11 OAG45584.1 - 5.4e-24 84.8 0.1 1.1e-23 83.7 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1214) DUF4449 PF14613.6 OAG45585.1 - 7.6e-07 29.4 0.3 7.6e-07 29.4 0.3 3.6 2 2 1 3 3 3 1 Protein of unknown function (DUF4449) FCD PF07729.12 OAG45585.1 - 0.13 12.7 2.1 0.46 10.9 0.0 2.7 2 1 0 2 2 2 0 FCD domain AbiH PF14253.6 OAG45585.1 - 0.16 11.8 1.1 0.36 10.7 0.7 1.6 1 1 0 1 1 1 0 Bacteriophage abortive infection AbiH Malic_M PF03949.15 OAG45586.1 - 7.5e-94 313.8 0.0 9.9e-94 313.4 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 OAG45586.1 - 5.9e-64 215.2 0.0 1e-63 214.4 0.0 1.4 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Mob1_phocein PF03637.17 OAG45587.1 - 5.8e-74 247.7 0.0 8.1e-74 247.2 0.0 1.1 1 0 0 1 1 1 1 Mob1/phocein family CDC45 PF02724.14 OAG45588.1 - 2.5 6.3 21.6 3.6 5.8 21.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Methyltransf_2 PF00891.18 OAG45589.1 - 2e-14 53.4 0.0 3.1e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain P_proprotein PF01483.20 OAG45589.1 - 0.14 12.2 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Proprotein convertase P-domain Methyltransf_23 PF13489.6 OAG45590.1 - 6.7e-21 74.8 0.0 1.2e-20 74.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG45590.1 - 8.5e-13 48.8 0.0 3.9e-12 46.7 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG45590.1 - 2.1e-10 41.1 0.0 5.8e-10 39.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG45590.1 - 1.3e-09 38.1 0.1 4.8e-08 32.9 0.1 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG45590.1 - 3.2e-07 31.0 0.0 2.4e-06 28.2 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 OAG45590.1 - 0.00026 20.5 0.0 0.00048 19.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 OAG45590.1 - 0.014 15.0 0.0 0.036 13.6 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_2 PF00891.18 OAG45590.1 - 0.043 13.1 0.0 0.073 12.4 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain CMAS PF02353.20 OAG45590.1 - 0.16 11.2 0.0 0.26 10.5 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase adh_short PF00106.25 OAG45592.1 - 1.9e-09 37.3 0.0 5.1e-06 26.1 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAG45592.1 - 1e-06 28.5 0.0 0.0068 16.0 0.0 2.1 1 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Ribosomal_L31 PF01197.18 OAG45593.1 - 0.023 14.9 0.0 0.048 13.9 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein L31 Vps5 PF09325.10 OAG45594.1 - 2e-87 292.7 2.2 2e-87 292.7 2.2 1.5 2 0 0 2 2 2 1 Vps5 C terminal like PX PF00787.24 OAG45594.1 - 5.1e-26 90.9 0.0 1.2e-25 89.7 0.0 1.6 1 0 0 1 1 1 1 PX domain BAR_3 PF16746.5 OAG45594.1 - 0.0012 18.6 3.1 0.027 14.2 1.4 2.4 1 1 1 2 2 2 2 BAR domain of APPL family Lipase_GDSL PF00657.22 OAG45594.1 - 0.064 13.2 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase BAR_3_WASP_bdg PF10456.9 OAG45594.1 - 0.088 12.3 0.2 1 8.8 0.0 2.1 1 1 1 2 2 2 0 WASP-binding domain of Sorting nexin protein AP3D1 PF06375.11 OAG45594.1 - 1.6 9.0 8.0 1.1 9.4 0.2 2.8 3 0 0 3 3 3 0 AP-3 complex subunit delta-1 Tautomerase_3 PF14832.6 OAG45595.1 - 0.001 19.3 0.1 0.014 15.7 0.0 2.3 2 0 0 2 2 2 1 Putative oxalocrotonate tautomerase enzyme TFIIE-A_C PF11521.8 OAG45595.1 - 0.063 13.6 0.3 0.2 12.0 0.3 1.8 1 0 0 1 1 1 0 C-terminal general transcription factor TFIIE alpha ATP-synt_DE_N PF02823.16 OAG45596.1 - 3.1e-13 49.4 0.0 6e-13 48.5 0.0 1.4 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain HECT_2 PF09814.9 OAG45597.1 - 9.4e-83 278.1 0.1 2.3e-80 270.3 0.1 2.0 1 1 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding PI-PLC-X PF00388.19 OAG45598.1 - 1.9e-59 199.4 0.0 2.8e-59 198.9 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 OAG45598.1 - 2e-42 144.1 0.2 4.8e-42 142.9 0.0 1.8 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, Y domain TPR_11 PF13414.6 OAG45600.1 - 0.0022 17.6 0.5 0.13 11.9 0.1 3.1 2 0 0 2 2 2 1 TPR repeat TPR_17 PF13431.6 OAG45600.1 - 0.0031 17.8 1.7 1.5 9.4 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat Nro1 PF12753.7 OAG45600.1 - 0.0047 15.9 0.8 0.016 14.2 0.1 2.0 2 1 0 2 2 2 1 Nuclear pore complex subunit Nro1 HLH PF00010.26 OAG45601.1 - 6.7e-13 48.4 0.0 2.1e-12 46.8 0.0 1.9 2 1 0 2 2 2 1 Helix-loop-helix DNA-binding domain HSP90 PF00183.18 OAG45602.1 - 2.6e-223 742.6 33.4 3.2e-223 742.3 33.4 1.0 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 OAG45602.1 - 5.6e-16 59.0 0.1 1e-15 58.2 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 OAG45602.1 - 1.1e-10 41.4 1.5 2.2e-10 40.5 0.1 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase LOH1CR12 PF10158.9 OAG45602.1 - 0.037 14.0 0.5 0.21 11.6 0.2 2.4 2 0 0 2 2 2 0 Tumour suppressor protein Cofac_haem_bdg PF04187.13 OAG45602.1 - 0.32 10.9 1.4 2.6 8.0 0.0 2.7 3 1 1 4 4 4 0 Haem-binding uptake, Tiki superfamily, ChaN DUF1676 PF07898.13 OAG45602.1 - 0.81 9.7 3.7 0.79 9.7 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1676) Rad54_N PF08658.10 OAG45602.1 - 1.3 9.1 11.5 0.078 13.1 0.5 2.8 2 0 0 2 2 2 0 Rad54 N terminal COPIIcoated_ERV PF07970.12 OAG45603.1 - 5.5e-84 281.4 0.0 8.8e-84 280.8 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 OAG45603.1 - 1.1e-26 92.9 0.0 2.3e-26 92.0 0.0 1.5 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) adh_short PF00106.25 OAG45604.1 - 1.7e-30 106.0 0.0 3e-30 105.1 0.0 1.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG45604.1 - 2.9e-22 79.4 0.8 3.3e-10 39.9 0.4 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG45604.1 - 0.00011 22.2 0.3 0.00081 19.3 0.1 2.0 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 OAG45604.1 - 0.003 17.0 0.1 0.032 13.7 0.1 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Methyltransf_25 PF13649.6 OAG45604.1 - 0.014 16.0 0.1 0.024 15.3 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase domain Vps53_N PF04100.12 OAG45605.1 - 5.4e-104 348.2 8.6 8.8e-104 347.5 8.6 1.3 1 0 0 1 1 1 1 Vps53-like, N-terminal DUF2451 PF10474.9 OAG45605.1 - 1.1e-07 31.8 0.0 3.8e-07 30.1 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) Vps54_N PF10475.9 OAG45605.1 - 2.9e-05 23.5 11.6 5.1e-05 22.7 11.6 1.3 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex COG2 PF06148.11 OAG45605.1 - 0.012 15.7 5.9 0.012 15.7 5.9 1.9 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Zw10 PF06248.13 OAG45605.1 - 0.15 10.6 12.2 0.61 8.6 12.4 1.7 1 1 0 1 1 1 0 Centromere/kinetochore Zw10 NBD94 PF16830.5 OAG45605.1 - 0.21 12.0 2.9 0.7 10.3 2.9 1.8 1 0 0 1 1 1 0 Nucleotide-Binding Domain 94 of RH FapA PF03961.13 OAG45605.1 - 0.24 9.9 4.4 0.39 9.3 4.4 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A CENP-F_leu_zip PF10473.9 OAG45605.1 - 1.7 8.7 15.4 1.5 8.9 12.5 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF445 PF04286.12 OAG45605.1 - 6.8 6.4 10.6 5.5 6.7 7.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF445) TAP_C PF03943.13 OAG45606.1 - 1.5e-13 50.1 0.4 2.9e-13 49.2 0.4 1.5 1 0 0 1 1 1 1 TAP C-terminal domain LRR_4 PF12799.7 OAG45606.1 - 1.7e-05 25.1 6.0 0.0029 18.0 0.3 3.0 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OAG45606.1 - 0.0048 16.6 2.3 0.014 15.1 2.0 2.0 1 1 0 1 1 1 1 Leucine rich repeat Lipase_3 PF01764.25 OAG45607.1 - 1.1e-18 67.4 0.0 6.9e-14 51.9 0.0 2.5 1 1 1 2 2 2 2 Lipase (class 3) Abhydrolase_6 PF12697.7 OAG45607.1 - 0.043 14.4 2.8 0.16 12.6 2.7 2.1 1 1 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAG45607.1 - 0.1 11.9 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 eIF-6 PF01912.18 OAG45608.1 - 3.3e-79 264.9 0.7 5.4e-79 264.2 0.7 1.3 1 0 0 1 1 1 1 eIF-6 family SRI PF08236.11 OAG45609.1 - 1.6e-21 76.3 14.0 1.6e-21 76.3 14.0 2.5 2 0 0 2 2 2 1 SRI (Set2 Rpb1 interacting) domain SET PF00856.28 OAG45609.1 - 8.1e-17 62.1 0.2 8.1e-17 62.1 0.2 3.8 4 1 0 4 4 4 1 SET domain AWS PF17907.1 OAG45609.1 - 2.6e-08 33.7 12.4 2.6e-08 33.7 12.4 1.9 2 0 0 2 2 2 1 AWS domain Med26 PF08711.11 OAG45609.1 - 9.9e-05 22.3 0.5 9.9e-05 22.3 0.5 2.2 2 0 0 2 2 2 1 TFIIS helical bundle-like domain TpcC PF12642.7 OAG45609.1 - 0.005 16.7 0.2 0.011 15.6 0.2 1.5 1 0 0 1 1 1 1 Conjugative transposon protein TcpC WW PF00397.26 OAG45609.1 - 0.0095 16.0 2.1 0.024 14.7 2.1 1.8 1 0 0 1 1 1 1 WW domain PGA2 PF07543.12 OAG45609.1 - 2.6 8.0 11.6 0.083 12.9 3.9 2.6 2 1 0 2 2 2 0 Protein trafficking PGA2 Pkinase PF00069.25 OAG45610.1 - 5.4e-55 186.6 0.0 1e-48 166.1 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAG45610.1 - 2.5e-34 118.8 0.4 1.5e-32 112.9 0.0 2.5 3 0 0 3 3 3 1 Protein tyrosine kinase Kinase-like PF14531.6 OAG45610.1 - 1.7e-07 30.9 0.0 1.7e-06 27.6 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 OAG45610.1 - 0.00012 22.1 0.6 0.0047 16.9 0.0 2.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OAG45610.1 - 0.1 11.4 0.0 0.1 11.4 0.0 2.6 3 0 0 3 3 3 0 Fungal protein kinase 7tm_2 PF00002.24 OAG45611.1 - 3.1e-06 26.7 8.5 3.4e-06 26.5 7.3 1.8 1 1 1 2 2 2 1 7 transmembrane receptor (Secretin family) Xpo1 PF08389.12 OAG45612.1 - 1.5e-36 125.7 0.4 9.6e-36 123.1 0.0 2.7 4 0 0 4 4 4 1 Exportin 1-like protein Ribosomal_L29e PF01779.17 OAG45612.1 - 3.1e-18 65.8 9.1 5.5e-18 65.0 9.1 1.5 1 0 0 1 1 1 1 Ribosomal L29e protein family MFS_1 PF07690.16 OAG45613.1 - 4.6e-34 117.9 34.0 6.7e-34 117.4 34.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 OAG45613.1 - 9.1e-10 37.6 0.5 9.1e-10 37.6 0.5 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 OAG45613.1 - 1.4e-07 30.8 1.6 1.4e-07 30.8 1.6 3.9 3 1 1 4 4 4 2 Sugar (and other) transporter Esterase PF00756.20 OAG45614.1 - 7.3e-50 169.9 1.4 2e-49 168.5 0.0 2.3 3 0 0 3 3 3 1 Putative esterase Esterase_phd PF10503.9 OAG45614.1 - 1.4e-05 24.8 0.0 0.00022 20.8 0.0 2.1 2 0 0 2 2 2 1 Esterase PHB depolymerase Hydrolase_4 PF12146.8 OAG45614.1 - 0.00044 19.6 0.0 0.0012 18.1 0.0 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 OAG45614.1 - 0.0012 18.7 0.0 0.0023 17.8 0.0 1.4 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 OAG45614.1 - 0.0019 17.7 0.0 0.0043 16.6 0.0 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family Chlorophyllase2 PF12740.7 OAG45614.1 - 0.0029 16.6 0.0 0.0056 15.6 0.0 1.5 1 1 0 1 1 1 1 Chlorophyllase enzyme PAF-AH_p_II PF03403.13 OAG45614.1 - 0.014 13.9 0.0 0.024 13.1 0.0 1.3 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II DUF676 PF05057.14 OAG45614.1 - 0.074 12.6 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Lipase_3 PF01764.25 OAG45614.1 - 0.12 12.3 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) zf-CCCH PF00642.24 OAG45615.1 - 9.5e-22 76.4 34.4 1.8e-07 30.9 0.9 5.2 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 OAG45615.1 - 9.7e-19 66.8 42.1 2.5e-06 27.3 2.6 5.3 5 0 0 5 5 5 5 Zinc finger domain Torus PF16131.5 OAG45615.1 - 1.9e-12 47.9 29.0 0.00021 21.9 2.8 5.4 1 1 4 5 5 5 5 Torus domain zf-CCCH_4 PF18044.1 OAG45615.1 - 4.8e-05 23.1 1.0 4.8e-05 23.1 1.0 5.2 5 0 0 5 5 5 2 CCCH-type zinc finger Ribosomal_60s PF00428.19 OAG45615.1 - 0.011 16.3 5.1 0.019 15.5 5.1 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein zf-CCCH_3 PF15663.5 OAG45615.1 - 0.37 11.0 24.9 0.28 11.4 5.2 4.2 1 1 4 5 5 5 0 Zinc-finger containing family Toxin_34 PF08396.10 OAG45615.1 - 0.58 11.0 14.4 1.1 10.1 9.2 2.9 2 1 1 3 3 3 0 Spider toxin omega agatoxin/Tx1 family zf-CCCH_2 PF14608.6 OAG45615.1 - 9.2 6.9 43.0 0.94 10.1 1.1 5.3 5 0 0 5 5 5 0 RNA-binding, Nab2-type zinc finger MFS_1 PF07690.16 OAG45616.1 - 2.2e-51 174.9 50.9 1.7e-48 165.4 51.8 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 OAG45616.1 - 2.1e-20 72.7 18.3 2.4e-20 72.5 17.7 1.4 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 OAG45616.1 - 2e-12 46.7 11.4 2e-12 46.7 11.4 3.9 3 1 0 4 4 4 2 Sugar (and other) transporter DUF3602 PF12223.8 OAG45617.1 - 3.8e-19 69.1 4.1 3.8e-19 69.1 4.1 3.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3602) PHD PF00628.29 OAG45617.1 - 0.00028 20.7 2.5 0.00028 20.7 2.5 2.1 2 0 0 2 2 2 1 PHD-finger DUF3484 PF11983.8 OAG45617.1 - 1.1 10.4 0.0 1.1 10.4 0.0 3.1 4 0 0 4 4 4 0 Membrane-attachment and polymerisation-promoting switch Mito_carr PF00153.27 OAG45618.1 - 7.1e-46 154.1 7.9 2e-18 66.1 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4203 PF13886.6 OAG45618.1 - 2.3 7.8 7.2 1.1 8.9 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4203) CBS PF00571.28 OAG45619.1 - 2.3e-06 28.0 0.0 0.1 13.1 0.1 3.0 2 1 0 2 2 2 2 CBS domain Beta-lactamase PF00144.24 OAG45619.1 - 0.077 12.2 0.1 3.8 6.7 0.1 2.1 1 1 1 2 2 2 0 Beta-lactamase Aa_trans PF01490.18 OAG45620.1 - 3.5e-25 88.6 27.9 4.1e-25 88.3 27.9 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein RBP_receptor PF14752.6 OAG45620.1 - 0.37 9.3 4.8 0.048 12.3 0.5 1.6 2 0 0 2 2 2 0 Retinol binding protein receptor Zip PF02535.22 OAG45621.1 - 9.6e-61 205.8 0.0 1.1e-60 205.6 0.0 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter UNC-50 PF05216.13 OAG45621.1 - 0.072 12.6 1.8 0.69 9.4 1.6 2.2 2 0 0 2 2 2 0 UNC-50 family Fungal_trans PF04082.18 OAG45622.1 - 1.5e-12 47.1 0.3 2.4e-12 46.5 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 OAG45622.1 - 6.9e-09 35.7 9.0 1.1e-05 25.6 1.1 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OAG45622.1 - 3.8e-08 33.4 8.7 7.6e-07 29.3 1.9 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 OAG45622.1 - 5.7e-06 26.7 7.6 0.0064 17.2 0.8 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2HC_2 PF13913.6 OAG45622.1 - 4.4e-05 23.3 6.3 0.00046 20.0 0.5 3.0 3 0 0 3 3 3 1 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.8 OAG45622.1 - 0.00096 19.4 1.0 0.078 13.3 0.2 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding DUF2321 PF10083.9 OAG45622.1 - 0.02 14.6 0.0 0.034 13.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) ADK_lid PF05191.14 OAG45622.1 - 0.033 14.2 0.3 0.39 10.7 0.1 2.5 1 1 1 2 2 2 0 Adenylate kinase, active site lid zf-Di19 PF05605.12 OAG45622.1 - 0.099 13.0 1.6 0.22 11.8 1.6 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 OAG45622.1 - 0.099 12.7 6.1 0.27 11.3 0.3 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.7 OAG45622.1 - 0.18 12.2 0.8 0.46 10.9 0.1 2.1 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 OAG45622.1 - 0.51 10.1 9.5 0.53 10.1 0.2 2.8 3 0 0 3 3 3 0 zinc-finger C2H2-type zf_C2H2_ZHX PF18387.1 OAG45622.1 - 3.5 7.3 5.5 0.46 10.2 0.1 2.3 2 1 1 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain FAD_binding_3 PF01494.19 OAG45623.1 - 1.2e-34 120.1 0.0 7.1e-19 68.2 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain F-box-like PF12937.7 OAG45624.1 - 0.029 14.3 0.2 0.069 13.1 0.1 1.7 2 0 0 2 2 2 0 F-box-like Acetyltransf_3 PF13302.7 OAG45625.1 - 1.1e-19 71.5 0.0 1.3e-19 71.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAG45625.1 - 5.3e-10 39.5 0.0 6.9e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 OAG45625.1 - 0.048 13.3 0.0 0.082 12.6 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 OAG45625.1 - 0.17 11.4 0.0 0.25 10.9 0.0 1.1 1 0 0 1 1 1 0 GNAT acetyltransferase PNTB PF02233.16 OAG45626.1 - 5.5e-175 582.7 25.6 5.5e-175 582.7 25.6 1.8 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.21 OAG45626.1 - 2.3e-73 246.0 1.1 4.1e-73 245.2 0.1 2.0 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 OAG45626.1 - 1.7e-44 151.4 0.1 3.7e-44 150.3 0.1 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain PNTB_4TM PF12769.7 OAG45626.1 - 8e-29 99.9 2.6 8e-29 99.9 2.6 5.2 3 2 3 6 6 6 1 4TM region of pyridine nucleotide transhydrogenase, mitoch 2-Hacid_dh_C PF02826.19 OAG45626.1 - 0.00022 20.6 0.2 1.3 8.4 0.1 3.5 3 1 1 4 4 4 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N PF00107.26 OAG45626.1 - 0.0033 17.4 0.1 0.017 15.1 0.1 2.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pyr_redox_2 PF07992.14 OAG45626.1 - 0.0043 16.3 0.2 0.009 15.3 0.2 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase TPP_enzyme_M PF00205.22 OAG45626.1 - 0.0077 16.0 0.7 0.067 12.9 0.4 2.8 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain NAD_binding_8 PF13450.6 OAG45626.1 - 1.9 8.8 4.5 0.61 10.4 0.6 2.4 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Cytochrom_B561 PF03188.16 OAG45628.1 - 5e-14 52.6 4.3 5e-14 52.6 4.3 1.9 2 1 1 3 3 3 1 Eukaryotic cytochrome b561 DUF2427 PF10348.9 OAG45628.1 - 0.004 16.9 2.0 0.004 16.9 2.0 3.1 2 1 1 3 3 3 1 Domain of unknown function (DUF2427) DUF4079 PF13301.6 OAG45628.1 - 0.12 12.5 17.1 0.26 11.4 4.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4079) DUF420 PF04238.12 OAG45628.1 - 7 6.9 19.5 0.092 13.0 7.9 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF420) DUF962 PF06127.11 OAG45629.1 - 2.1e-26 91.8 0.0 3.9e-26 91.0 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF962) Stevor PF17410.2 OAG45629.1 - 0.21 11.1 0.1 0.37 10.3 0.1 1.3 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame BLOC1_2 PF10046.9 OAG45630.1 - 0.76 10.1 9.3 7.7 6.9 1.0 3.4 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 UPF0449 PF15136.6 OAG45630.1 - 1.2 9.7 10.6 0.25 11.8 1.0 3.6 2 1 2 4 4 4 0 Uncharacterised protein family UPF0449 DUF1192 PF06698.11 OAG45630.1 - 1.5 8.9 7.2 0.23 11.6 0.7 3.2 2 2 1 3 3 3 0 Protein of unknown function (DUF1192) NPV_P10 PF05531.12 OAG45630.1 - 2.3 8.7 14.3 3.7 8.1 1.1 4.6 2 1 2 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF3802 PF12290.8 OAG45630.1 - 8.7 6.9 9.7 67 4.0 0.5 3.8 2 2 1 4 4 4 0 Protein of unknown function (DUF3802) E1-E2_ATPase PF00122.20 OAG45631.1 - 2.4e-36 124.9 8.3 1.4e-30 106.2 0.2 4.1 5 0 0 5 5 5 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 OAG45631.1 - 8.5e-32 110.3 0.8 8.5e-32 110.3 0.8 2.4 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 OAG45631.1 - 1.1e-18 68.4 0.2 1.8e-14 54.6 0.1 3.3 3 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 OAG45631.1 - 2.1e-18 66.2 0.0 5.2e-18 64.9 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 OAG45631.1 - 1.1e-15 57.0 0.0 3.2e-15 55.6 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 OAG45631.1 - 9e-05 22.3 1.9 0.0024 17.7 0.6 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase 3HCDH PF00725.22 OAG45632.1 - 8.4e-23 80.8 0.0 1.7e-22 79.9 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 3HCDH_N PF02737.18 OAG45632.1 - 5.5e-20 72.0 0.0 4.7e-19 69.0 0.0 2.3 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MFS_1 PF07690.16 OAG45633.1 - 2.7e-26 92.3 35.0 8.3e-26 90.7 34.8 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF2093 PF09866.9 OAG45633.1 - 0.24 10.9 3.0 4.3 6.9 1.2 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2093) G0-G1_switch_2 PF15103.6 OAG45633.1 - 6 7.4 4.7 43 4.6 0.3 2.8 3 0 0 3 3 3 0 G0/G1 switch protein 2 adh_short PF00106.25 OAG45634.1 - 9.9e-31 106.7 0.0 1.8e-23 83.0 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAG45634.1 - 3.5e-22 79.1 0.0 9.6e-20 71.1 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG45634.1 - 0.006 16.5 0.0 0.019 14.9 0.0 1.8 2 1 0 2 2 2 1 KR domain Fungal_trans PF04082.18 OAG45635.1 - 1.6e-15 56.9 1.4 3.8e-15 55.6 0.4 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Methyltransf_23 PF13489.6 OAG45636.1 - 1.6e-17 63.8 0.0 2.4e-17 63.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAG45636.1 - 3.5e-17 62.8 0.0 8.2e-17 61.6 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAG45636.1 - 2.4e-14 53.4 0.0 3.4e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAG45636.1 - 3.9e-14 53.1 0.0 9.9e-14 51.8 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAG45636.1 - 9e-13 48.8 0.0 1.7e-12 47.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 OAG45636.1 - 7.8e-07 28.8 0.0 1.1e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 OAG45636.1 - 0.0002 20.9 0.0 0.00036 20.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 OAG45636.1 - 0.039 14.0 0.1 0.076 13.0 0.0 1.5 2 0 0 2 2 2 0 Methyltransferase domain V_cholerae_RfbT PF05575.11 OAG45636.1 - 0.2 10.9 0.0 0.28 10.4 0.0 1.1 1 0 0 1 1 1 0 Vibrio cholerae RfbT protein DUF1759 PF03564.15 OAG45637.1 - 0.015 15.2 3.5 0.033 14.1 3.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1759) HTH_57 PF18679.1 OAG45637.1 - 0.31 11.4 2.6 0.66 10.3 2.6 1.6 1 0 0 1 1 1 0 ThcOx helix turn helix domain Raptor_N PF14538.6 OAG45637.1 - 0.62 10.0 2.7 2.7 7.9 0.6 2.3 2 0 0 2 2 2 0 Raptor N-terminal CASPase like domain Prominin PF05478.11 OAG45637.1 - 0.79 7.6 6.2 1.1 7.1 6.2 1.3 1 0 0 1 1 1 0 Prominin FAM76 PF16046.5 OAG45637.1 - 1.5 8.1 17.9 0.14 11.5 11.8 2.0 2 0 0 2 2 2 0 FAM76 protein Spc7 PF08317.11 OAG45637.1 - 6.3 5.6 28.5 0.28 10.0 20.3 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein BRAP2 PF07576.12 OAG45638.1 - 2.6e-25 88.5 0.0 4.4e-25 87.8 0.0 1.2 1 0 0 1 1 1 1 BRCA1-associated protein 2 Cu_amine_oxid PF01179.20 OAG45639.1 - 1.9e-07 30.4 2.7 0.0072 15.3 3.2 4.1 2 1 0 2 2 2 2 Copper amine oxidase, enzyme domain ubiquitin PF00240.23 OAG45640.1 - 5.4e-102 333.6 13.3 1.9e-33 114.0 0.6 3.0 3 0 0 3 3 3 3 Ubiquitin family Rad60-SLD PF11976.8 OAG45640.1 - 1.3e-48 162.7 13.8 1.2e-15 57.1 0.7 3.0 3 0 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 OAG45640.1 - 7.5e-18 64.8 6.1 0.00026 21.4 0.1 4.6 3 3 0 3 3 3 3 Ubiquitin-like domain Ubiquitin_5 PF18037.1 OAG45640.1 - 1.6e-12 47.6 2.3 0.014 15.7 0.1 3.1 1 1 2 3 3 3 3 Ubiquitin-like domain TBK1_ULD PF18396.1 OAG45640.1 - 1.7e-12 47.1 1.7 0.016 15.1 0.1 3.2 3 0 0 3 3 3 3 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 OAG45640.1 - 4.7e-11 42.8 1.3 0.073 13.2 0.0 3.9 3 3 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 OAG45640.1 - 7.2e-10 39.4 0.3 0.21 12.1 0.0 3.2 1 1 1 3 3 3 3 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 OAG45640.1 - 1.7e-08 34.4 0.3 0.3 10.9 0.0 3.1 1 1 2 3 3 3 3 Silencing defective 2 N-terminal ubiquitin domain Ubiquitin_4 PF18036.1 OAG45640.1 - 2.4e-06 27.5 16.0 11 6.1 0.2 6.0 6 0 0 6 6 6 0 Ubiquitin-like domain DUF3861 PF12977.7 OAG45640.1 - 8.5e-05 22.7 1.0 8 6.7 0.0 3.2 3 0 0 3 3 3 0 Domain of Unknown Function with PDB structure (DUF3861) ACT_5 PF13710.6 OAG45640.1 - 0.00015 21.5 2.1 6.9 6.6 0.0 3.3 3 0 0 3 3 3 0 ACT domain DUF2870 PF11069.8 OAG45640.1 - 0.00027 21.2 0.0 20 5.6 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2870) Methyltrans_RNA PF04452.14 OAG45640.1 - 0.00058 19.3 0.1 1.1 8.5 0.0 2.4 2 0 0 2 2 2 2 RNA methyltransferase Big_7 PF17957.1 OAG45640.1 - 0.0011 19.6 0.1 34 5.3 0.0 3.2 3 0 0 3 3 3 0 Bacterial Ig domain YcgR_2 PF12945.7 OAG45640.1 - 0.003 17.7 2.9 19 5.5 0.1 3.3 3 0 0 3 3 3 0 Flagellar protein YcgR UDP-g_GGTase PF06427.11 OAG45640.1 - 0.0069 16.5 3.0 4.5 7.4 0.0 3.1 4 0 0 4 4 3 2 UDP-glucose:Glycoprotein Glucosyltransferase DUF969 PF06149.12 OAG45640.1 - 0.0076 15.7 0.0 15 5.0 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF969) DUF493 PF04359.14 OAG45640.1 - 0.031 14.9 0.0 95 3.7 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF493) Raf1_HTH PF18579.1 OAG45640.1 - 0.031 14.0 0.0 71 3.2 0.0 3.2 3 0 0 3 3 3 0 Rubisco accumulation factor 1 helix turn helix domain ACT_4 PF13291.6 OAG45640.1 - 0.032 14.8 0.3 96 3.7 0.0 3.3 3 0 0 3 3 3 0 ACT domain ORF11CD3 PF10549.9 OAG45640.1 - 0.088 12.9 0.0 62 3.8 0.0 3.4 3 0 0 3 3 3 0 ORF11CD3 domain ProRS-C_2 PF09181.10 OAG45640.1 - 0.12 12.5 2.6 72 3.6 0.1 3.2 3 0 0 3 3 3 0 Prolyl-tRNA synthetase, C-terminal Tash_PEST PF07708.11 OAG45640.1 - 0.13 12.4 18.4 4.5 7.6 1.4 3.3 3 0 0 3 3 3 0 Tash protein PEST motif Myosin_N PF02736.19 OAG45640.1 - 0.27 11.1 3.4 76 3.3 0.0 4.3 3 0 0 3 3 3 0 Myosin N-terminal SH3-like domain DMA PF03474.14 OAG45640.1 - 0.44 10.2 1.7 1.1e+02 2.5 0.0 3.2 3 0 0 3 3 3 0 DMRTA motif Plexin_cytopl PF08337.12 OAG45640.1 - 0.53 8.9 10.5 8.3 4.9 0.4 3.9 2 1 1 4 4 4 0 Plexin cytoplasmic RasGAP domain PI3K_p85B PF02192.16 OAG45640.1 - 0.85 9.4 5.0 67 3.3 0.1 3.3 3 0 0 3 3 3 0 PI3-kinase family, p85-binding domain FlgD_ig PF13860.6 OAG45640.1 - 2.8 7.9 4.9 1.2e+02 2.6 0.1 3.3 3 0 0 3 3 3 0 FlgD Ig-like domain Acyl_transf_3 PF01757.22 OAG45642.1 - 5.5e-14 52.0 18.4 7e-14 51.6 18.4 1.2 1 0 0 1 1 1 1 Acyltransferase family TMEM220 PF15071.6 OAG45642.1 - 0.31 11.8 3.5 2.6 8.8 2.9 2.5 2 0 0 2 2 2 0 Transmembrane family 220, helix Fungal_trans PF04082.18 OAG45643.1 - 1.1e-27 96.7 0.4 2e-27 95.9 0.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAG45643.1 - 7e-07 29.3 8.0 1.3e-06 28.4 8.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.24 OAG45644.1 - 1.6e-66 225.1 21.0 1.8e-66 224.9 21.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG45644.1 - 5.9e-22 78.1 25.5 8.4e-22 77.6 25.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG45645.1 - 3.8e-07 29.3 3.2 3.8e-07 29.3 1.8 1.6 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG45645.1 - 6.9e-05 21.9 0.1 8.1e-05 21.7 0.1 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily IRK PF01007.20 OAG45645.1 - 0.005 16.7 1.6 0.0076 16.1 1.6 1.2 1 0 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain DUF218 PF02698.17 OAG45647.1 - 2.1e-05 24.5 0.0 3.1e-05 24.0 0.0 1.3 1 1 0 1 1 1 1 DUF218 domain Peptidase_S9 PF00326.21 OAG45648.1 - 4e-54 183.3 1.7 7e-54 182.5 1.7 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family MFS_1 PF07690.16 OAG45648.1 - 1.3e-16 60.5 50.0 6e-11 41.9 30.0 2.7 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.13 OAG45648.1 - 2.1e-06 26.5 20.3 2.1e-06 26.5 20.3 1.4 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) PD40 PF07676.12 OAG45648.1 - 0.0097 15.8 2.6 0.52 10.3 0.1 3.5 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat DUF1772 PF08592.11 OAG45649.1 - 2.3e-18 66.8 3.8 2.9e-18 66.5 3.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) Zn_clus PF00172.18 OAG45651.1 - 9.9e-05 22.4 7.3 0.00025 21.1 7.3 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.32 OAG45652.1 - 9.3e-32 108.6 19.6 1.5e-07 31.9 0.1 8.0 7 1 0 7 7 7 5 WD domain, G-beta repeat PRP4 PF08799.11 OAG45652.1 - 2.2e-14 52.7 3.4 2.2e-14 52.7 3.4 2.1 2 0 0 2 2 2 1 pre-mRNA processing factor 4 (PRP4) like ANAPC4_WD40 PF12894.7 OAG45652.1 - 9e-12 45.1 0.1 0.38 11.1 0.0 5.8 4 1 2 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain AAA_32 PF13654.6 OAG45653.1 - 0.0023 16.8 7.4 0.004 16.0 7.4 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OAG45653.1 - 0.019 15.3 0.1 0.078 13.4 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain NB-ARC PF00931.22 OAG45653.1 - 0.025 13.8 0.1 0.26 10.5 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain ABC_tran PF00005.27 OAG45653.1 - 0.029 14.9 2.1 0.36 11.3 0.0 2.9 2 1 1 3 3 3 0 ABC transporter NACHT PF05729.12 OAG45653.1 - 0.042 13.8 0.1 0.14 12.0 0.1 1.9 1 1 0 1 1 1 0 NACHT domain RNA_helicase PF00910.22 OAG45653.1 - 0.058 13.8 0.0 0.17 12.3 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_23 PF13476.6 OAG45653.1 - 0.61 10.6 3.5 4.2 7.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain Translin PF01997.16 OAG45653.1 - 1 9.3 5.6 0.43 10.5 0.3 2.2 2 0 0 2 2 2 0 Translin family PHM7_cyt PF14703.6 OAG45653.1 - 8 6.7 8.0 45 4.2 7.5 2.6 2 1 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter PS_Dcarbxylase PF02666.15 OAG45654.1 - 5.2e-44 150.2 0.0 8.3e-44 149.5 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Thiolase_N PF00108.23 OAG45655.1 - 5.1e-65 219.4 0.0 6.1e-65 219.2 0.0 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 OAG45655.1 - 6.4e-19 67.8 0.0 1.1e-18 67.0 0.0 1.4 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III PF08545.10 OAG45655.1 - 0.00057 19.7 0.1 0.067 13.1 0.0 2.3 2 0 0 2 2 2 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.26 OAG45655.1 - 0.015 14.9 0.5 0.055 13.0 0.4 1.9 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain DUF2070 PF09843.9 OAG45656.1 - 0.21 9.8 0.0 0.26 9.5 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) MFS_1 PF07690.16 OAG45658.1 - 1.7e-41 142.3 45.3 9.6e-41 139.9 45.8 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 OAG45658.1 - 1.4e-08 33.7 12.7 1.8e-08 33.3 12.1 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Phage_holin_5_1 PF06946.11 OAG45658.1 - 0.56 10.6 8.3 8.5 6.8 1.5 3.3 2 1 0 2 2 2 0 Bacteriophage A118-like holin, Hol118 DUF2534 PF10749.9 OAG45658.1 - 2.7 8.2 6.3 2.8 8.2 0.2 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2534) PMP1_2 PF08114.11 OAG45658.1 - 9 6.1 11.7 29 4.5 1.7 4.2 3 0 0 3 3 3 0 ATPase proteolipid family DUF3453 PF11935.8 OAG45659.1 - 6.8e-70 235.2 1.4 1.9e-69 233.7 0.9 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3453) DUF615 PF04751.14 OAG45659.1 - 0.052 13.5 0.0 3.8 7.5 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF615) DUF917 PF06032.12 OAG45660.1 - 2.6e-110 368.6 0.3 8.2e-110 366.9 0.0 2.0 3 0 0 3 3 3 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.18 OAG45660.1 - 4.4e-28 98.4 5.6 2.8e-24 85.9 0.5 3.4 2 1 1 3 3 3 3 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 OAG45660.1 - 3.9e-27 95.1 0.9 3.3e-24 85.6 0.1 2.8 2 1 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region MutL PF13941.6 OAG45660.1 - 1.6e-06 27.1 1.8 0.01 14.5 0.0 2.3 2 0 0 2 2 2 2 MutL protein PGM_PMM_I PF02878.16 OAG45660.1 - 0.04 13.6 1.1 0.26 11.0 0.2 2.7 4 0 0 4 4 4 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I FtsA PF14450.6 OAG45660.1 - 0.24 11.8 7.8 0.81 10.1 0.3 3.6 4 1 0 4 4 4 0 Cell division protein FtsA Transp_cyt_pur PF02133.15 OAG45661.1 - 4e-104 348.8 41.2 4.9e-104 348.5 41.2 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin CcmD PF04995.14 OAG45661.1 - 0.063 13.4 0.0 0.063 13.4 0.0 4.5 5 1 1 6 6 6 0 Heme exporter protein D (CcmD) HET PF06985.11 OAG45662.1 - 6.6e-22 78.4 0.0 1.5e-21 77.3 0.0 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF4440 PF14534.6 OAG45663.1 - 0.046 14.1 0.2 0.24 11.8 0.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4440) ACT_3 PF10000.9 OAG45665.1 - 1.8e-11 43.8 0.1 2e-10 40.4 0.1 2.5 1 1 0 1 1 1 1 ACT domain ACT_7 PF13840.6 OAG45665.1 - 6.4e-10 38.7 0.0 9.8e-10 38.1 0.0 1.3 1 0 0 1 1 1 1 ACT domain DNA_mis_repair PF01119.19 OAG45666.1 - 1.4e-11 44.1 0.0 2.7e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 OAG45666.1 - 1.6e-10 40.9 0.6 9.3e-10 38.5 0.3 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 OAG45666.1 - 4.9e-07 30.2 0.1 1.6e-06 28.6 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DHHC PF01529.20 OAG45667.1 - 0.31 11.1 0.5 0.45 10.6 0.5 1.2 1 0 0 1 1 1 0 DHHC palmitoyltransferase DHDPS PF00701.22 OAG45668.1 - 9.8e-37 126.2 0.0 1.2e-36 125.9 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family FAD_binding_4 PF01565.23 OAG45669.1 - 5.7e-08 32.6 0.1 0.0024 17.6 0.1 2.3 2 0 0 2 2 2 2 FAD binding domain ALO PF04030.14 OAG45669.1 - 0.00021 21.2 3.3 0.0015 18.4 0.3 2.2 2 0 0 2 2 2 1 D-arabinono-1,4-lactone oxidase Chol_subst-bind PF09129.11 OAG45669.1 - 2 7.3 6.2 1.1 8.1 0.4 2.7 2 1 0 2 2 2 0 Cholesterol oxidase, substrate-binding 2-Hacid_dh_C PF02826.19 OAG45670.1 - 1.1e-39 135.7 2.7 1.4e-26 92.9 0.0 3.2 3 2 1 4 4 4 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 OAG45670.1 - 0.014 15.1 0.0 0.023 14.4 0.0 1.4 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AdoHcyase_NAD PF00670.21 OAG45670.1 - 0.099 12.7 0.1 0.25 11.4 0.2 1.5 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Pkinase PF00069.25 OAG45671.1 - 2.1e-71 240.4 0.1 3e-71 239.9 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG45671.1 - 1.9e-46 158.4 0.4 2.9e-46 157.9 0.4 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAG45671.1 - 8.3e-07 28.6 0.0 0.00017 21.0 0.0 2.2 2 0 0 2 2 2 2 Kinase-like POLO_box PF00659.18 OAG45671.1 - 2.2e-06 27.8 0.0 0.067 13.4 0.0 2.6 2 0 0 2 2 2 2 POLO box duplicated region Kdo PF06293.14 OAG45671.1 - 0.024 14.0 0.1 0.072 12.4 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OAG45671.1 - 0.035 13.1 0.1 0.058 12.3 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 OAG45671.1 - 0.18 10.6 4.2 0.079 11.7 0.1 2.0 2 0 0 2 2 2 0 Fungal protein kinase OPA3 PF07047.12 OAG45672.1 - 2.4e-47 159.8 2.3 2.4e-47 159.8 2.3 1.8 2 0 0 2 2 2 1 Optic atrophy 3 protein (OPA3) Med11 PF10280.9 OAG45672.1 - 0.018 15.5 1.2 0.018 15.5 1.2 2.7 2 2 0 2 2 2 0 Mediator complex protein BatD PF13584.6 OAG45672.1 - 0.019 13.8 1.4 0.029 13.2 1.4 1.3 1 0 0 1 1 1 0 Oxygen tolerance Ribosomal_S2 PF00318.20 OAG45672.1 - 0.1 11.8 0.1 0.1 11.8 0.1 2.0 3 0 0 3 3 3 0 Ribosomal protein S2 Herpes_UL37_1 PF03970.13 OAG45673.1 - 0.059 12.6 0.0 0.074 12.2 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL37 tegument protein DUF3328 PF11807.8 OAG45674.1 - 3.9e-47 160.9 1.0 4.8e-47 160.6 1.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Myosin_head PF00063.21 OAG45676.1 - 2.6e-239 796.0 3.2 3.1e-239 795.7 3.2 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 OAG45676.1 - 4.5e-49 166.7 0.0 8.9e-49 165.7 0.0 1.5 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding SH3_1 PF00018.28 OAG45676.1 - 2.5e-11 43.0 0.1 6.1e-11 41.8 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 OAG45676.1 - 4.8e-10 39.1 0.1 1.5e-09 37.6 0.1 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 OAG45676.1 - 2.4e-09 36.7 0.6 5.7e-09 35.5 0.1 1.9 2 0 0 2 2 1 1 Variant SH3 domain Hpr_kinase_C PF07475.12 OAG45676.1 - 0.015 14.8 0.6 3 7.3 0.0 2.7 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain AAA_22 PF13401.6 OAG45676.1 - 0.019 15.2 0.0 0.05 13.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain IQ PF00612.27 OAG45676.1 - 0.024 14.4 8.3 1.3 9.0 1.0 2.8 1 1 1 2 2 2 0 IQ calmodulin-binding motif AAA_16 PF13191.6 OAG45676.1 - 0.03 14.7 0.0 0.08 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain hSH3 PF14603.6 OAG45676.1 - 0.063 13.7 0.0 0.18 12.2 0.0 1.8 1 0 0 1 1 1 0 Helically-extended SH3 domain SH3_3 PF08239.11 OAG45676.1 - 0.18 12.1 0.2 0.47 10.8 0.2 1.7 1 0 0 1 1 1 0 Bacterial SH3 domain NACHT PF05729.12 OAG45676.1 - 0.19 11.6 0.1 0.51 10.2 0.1 1.7 2 0 0 2 2 2 0 NACHT domain PRC PF05239.16 OAG45677.1 - 0.036 14.1 0.6 1 9.5 0.0 2.7 3 0 0 3 3 3 0 PRC-barrel domain adh_short PF00106.25 OAG45678.1 - 9.9e-33 113.2 1.1 1.3e-32 112.9 1.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAG45678.1 - 4.7e-18 65.6 0.4 7.5e-18 64.9 0.4 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAG45678.1 - 3.2e-12 46.7 0.2 4.3e-12 46.3 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAG45678.1 - 5.8e-08 32.5 0.1 8.2e-08 32.0 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 OAG45678.1 - 9e-07 28.3 0.1 1.1e-06 28.0 0.1 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 OAG45678.1 - 1.3e-05 24.7 0.0 2.8e-05 23.7 0.0 1.5 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Shikimate_DH PF01488.20 OAG45678.1 - 0.0031 17.6 0.8 0.03 14.4 0.5 2.1 1 1 1 2 2 2 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 OAG45678.1 - 0.014 16.0 0.4 0.026 15.1 0.4 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 OAG45678.1 - 0.014 15.0 0.1 0.024 14.3 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Sacchrp_dh_NADP PF03435.18 OAG45678.1 - 0.018 15.3 0.1 0.03 14.6 0.1 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain 2-Hacid_dh_C PF02826.19 OAG45678.1 - 0.03 13.7 0.0 0.42 10.0 0.0 2.1 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF723 PF05265.13 OAG45678.1 - 0.033 14.1 0.1 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF723) NmrA PF05368.13 OAG45678.1 - 0.055 13.0 0.6 0.094 12.3 0.6 1.3 1 0 0 1 1 1 0 NmrA-like family 3HCDH_N PF02737.18 OAG45678.1 - 0.056 13.3 0.2 0.1 12.5 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.17 OAG45678.1 - 0.062 12.4 0.0 0.082 12.0 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Glyco_tran_WecB PF03808.13 OAG45678.1 - 0.075 13.0 0.0 0.18 11.7 0.0 1.6 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family NAD_binding_3 PF03447.16 OAG45678.1 - 0.076 13.7 0.0 0.16 12.6 0.0 1.5 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain DapB_N PF01113.20 OAG45678.1 - 0.076 13.1 0.1 0.15 12.2 0.1 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Rossmann-like PF10727.9 OAG45678.1 - 0.078 12.8 0.2 0.18 11.6 0.2 1.6 1 0 0 1 1 1 0 Rossmann-like domain ThiF PF00899.21 OAG45678.1 - 1.8 7.9 3.6 2.3 7.5 2.5 1.7 1 1 1 2 2 2 0 ThiF family MS_channel PF00924.18 OAG45679.1 - 9.2e-24 84.1 0.8 1.6e-23 83.3 0.8 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_5 PF13202.6 OAG45679.1 - 5.5e-05 22.5 0.0 0.00015 21.1 0.0 1.8 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.32 OAG45679.1 - 0.00047 19.5 0.3 0.0012 18.2 0.3 1.8 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 OAG45679.1 - 0.00088 19.0 0.1 0.0035 17.2 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 OAG45679.1 - 0.0069 16.8 0.2 0.021 15.3 0.2 1.8 1 0 0 1 1 1 1 EF-hand domain pair Phage_1_1 PF08200.11 OAG45679.1 - 0.053 13.9 1.6 0.15 12.5 1.6 1.8 1 0 0 1 1 1 0 Bacteriophage 1.1 Protein DUF3671 PF12420.8 OAG45679.1 - 5.3 7.2 7.6 2.6 8.1 0.1 3.1 2 1 1 3 3 3 0 Protein of unknown function Tubulin PF00091.25 OAG45680.1 - 7.3e-65 218.9 0.0 9.9e-65 218.4 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 OAG45680.1 - 1.6e-44 151.1 0.0 2.5e-44 150.4 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 OAG45680.1 - 0.00053 19.7 0.0 0.00093 18.9 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain EMP24_GP25L PF01105.24 OAG45681.1 - 0.00021 21.3 2.3 0.00039 20.4 0.2 2.3 2 1 0 2 2 2 1 emp24/gp25L/p24 family/GOLD TACC_C PF05010.14 OAG45681.1 - 0.033 14.0 1.8 0.069 12.9 0.8 1.9 2 0 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF2207 PF09972.9 OAG45681.1 - 0.047 12.4 0.0 0.07 11.9 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) PTRF_SDPR PF15237.6 OAG45681.1 - 0.054 13.1 3.4 0.034 13.8 0.9 1.9 2 0 0 2 2 2 0 PTRF/SDPR family DUF3552 PF12072.8 OAG45681.1 - 0.11 11.9 9.4 0.3 10.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) DotU PF09850.9 OAG45681.1 - 0.17 11.5 1.4 0.38 10.4 0.3 2.1 2 0 0 2 2 2 0 Type VI secretion system protein DotU Nup88 PF10168.9 OAG45681.1 - 0.18 9.6 3.8 0.26 9.0 3.8 1.2 1 0 0 1 1 1 0 Nuclear pore component DUF4337 PF14235.6 OAG45681.1 - 0.23 11.6 0.6 0.59 10.2 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) VIT1 PF01988.19 OAG45681.1 - 0.44 10.4 1.6 1.3 8.9 1.7 1.7 1 1 0 1 1 1 0 VIT family MCU PF04678.13 OAG45681.1 - 0.65 10.1 2.4 2.7 8.0 1.6 2.3 1 1 1 2 2 2 0 Mitochondrial calcium uniporter V_ATPase_I PF01496.19 OAG45681.1 - 8.2 4.2 7.7 0.32 8.9 0.4 1.9 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family FUSC PF04632.12 OAG45681.1 - 8.5 4.8 7.3 20 3.5 6.5 1.8 1 1 1 2 2 2 0 Fusaric acid resistance protein family Cys_Met_Meta_PP PF01053.20 OAG45682.1 - 6.2e-140 466.1 0.0 7.1e-140 465.9 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 OAG45682.1 - 1.1e-08 34.6 0.1 1.9e-08 33.9 0.1 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 OAG45682.1 - 3.8e-06 26.1 0.4 6.9e-06 25.3 0.1 1.4 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 OAG45682.1 - 6.2e-06 25.8 0.1 1.1e-05 24.9 0.1 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 OAG45682.1 - 0.047 13.0 0.1 0.099 11.9 0.1 1.6 1 1 0 1 1 1 0 Beta-eliminating lyase RNA_pol_Rbc25 PF08292.12 OAG45683.1 - 4e-29 101.5 0.1 4.6e-29 101.3 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 S1 PF00575.23 OAG45683.1 - 0.01 16.2 0.0 0.02 15.2 0.0 1.5 1 0 0 1 1 1 1 S1 RNA binding domain Adenosine_kin PF04008.14 OAG45684.1 - 9.5e-75 249.6 0.0 1.1e-74 249.4 0.0 1.0 1 0 0 1 1 1 1 Adenosine specific kinase NUFIP1 PF10453.9 OAG45685.1 - 1.5e-08 34.3 10.7 9.3e-08 31.8 10.7 2.4 1 1 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-CCCH_4 PF18044.1 OAG45685.1 - 4.5e-06 26.3 2.7 6.8e-06 25.8 2.7 1.3 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 OAG45685.1 - 2.7e-05 23.9 1.7 5e-05 23.1 1.7 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 OAG45685.1 - 0.00018 21.4 8.4 0.00029 20.8 8.4 1.3 1 0 0 1 1 1 1 Zinc finger domain Torus PF16131.5 OAG45685.1 - 0.036 14.8 0.0 0.036 14.8 0.0 2.5 2 1 0 2 2 2 0 Torus domain AAA_13 PF13166.6 OAG45685.1 - 3.9 6.0 14.1 5.5 5.5 14.1 1.1 1 0 0 1 1 1 0 AAA domain Abhydrolase_3 PF07859.13 OAG45686.1 - 3.3e-14 53.2 0.6 9.1e-10 38.7 0.1 3.9 2 1 0 2 2 2 2 alpha/beta hydrolase fold HU-CCDC81_bac_2 PF18175.1 OAG45687.1 - 0.23 11.4 1.2 1 9.3 0.0 2.2 2 0 0 2 2 2 0 CCDC81-like prokaryotic HU domain 2 Sortilin-Vps10 PF15902.5 OAG45688.1 - 3.8e-295 978.5 1.8 2.2e-153 511.3 0.5 2.1 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 OAG45688.1 - 4.2e-96 320.1 12.7 2.1e-49 168.1 2.4 2.4 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 OAG45688.1 - 3e-13 47.6 36.3 0.23 11.6 0.1 11.4 11 0 0 11 11 11 6 BNR/Asp-box repeat PSII_BNR PF14870.6 OAG45688.1 - 2.4e-07 30.3 1.0 0.14 11.3 0.0 5.0 4 2 0 4 4 4 2 Photosynthesis system II assembly factor YCF48 BNR_2 PF13088.6 OAG45688.1 - 0.0018 17.6 7.9 7.4 5.8 0.0 6.8 5 4 0 7 7 7 1 BNR repeat-like domain DUF2167 PF09935.9 OAG45688.1 - 0.14 11.3 0.1 16 4.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2167) CHB_HEX_C PF03174.13 OAG45688.1 - 0.15 12.0 2.9 5.2 7.1 0.0 4.2 6 0 0 6 6 6 0 Chitobiase/beta-hexosaminidase C-terminal domain BNR_6 PF15899.5 OAG45688.1 - 0.77 10.0 11.2 39 4.7 0.1 6.2 6 0 0 6 6 6 0 BNR-Asp box repeat GPI-anchored PF10342.9 OAG45690.1 - 1.5e-14 54.5 0.1 1.5e-14 54.5 0.1 3.2 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family SOG2 PF10428.9 OAG45690.1 - 0.3 10.2 20.6 0.33 10.1 20.6 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein AF-4 PF05110.13 OAG45690.1 - 0.73 7.9 19.5 0.76 7.8 19.5 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Macoilin PF09726.9 OAG45690.1 - 1.6 7.2 11.0 1.7 7.1 11.0 1.0 1 0 0 1 1 1 0 Macoilin family Smg8_Smg9 PF10220.9 OAG45690.1 - 2.5 6.3 4.8 2.7 6.2 4.8 1.0 1 0 0 1 1 1 0 Smg8_Smg9 SPX PF03105.19 OAG45690.1 - 6.8 6.5 14.5 8.1 6.2 14.5 1.1 1 0 0 1 1 1 0 SPX domain Presenilin PF01080.17 OAG45690.1 - 8 5.1 8.3 10 4.7 8.3 1.1 1 0 0 1 1 1 0 Presenilin Apt1 PF10351.9 OAG45690.1 - 8.5 5.1 15.4 10 4.8 15.4 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF1752 PF08550.10 OAG45691.1 - 4.3e-09 36.1 3.8 8.2e-09 35.2 3.8 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) SUI1 PF01253.22 OAG45692.1 - 4.5e-25 88.0 0.0 1.1e-24 86.7 0.0 1.7 1 0 0 1 1 1 1 Translation initiation factor SUI1 TnpV PF14198.6 OAG45692.1 - 0.011 15.8 0.4 0.017 15.1 0.4 1.4 1 0 0 1 1 1 0 Transposon-encoded protein TnpV tRNA_edit PF04073.15 OAG45692.1 - 0.027 14.5 2.0 0.042 13.9 2.0 1.3 1 0 0 1 1 1 0 Aminoacyl-tRNA editing domain DUF3361 PF11841.8 OAG45693.1 - 6.9e-06 26.1 0.0 1.1e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3361) ELMO_CED12 PF04727.13 OAG45694.1 - 5.6e-47 160.1 0.1 8.9e-47 159.5 0.1 1.3 1 0 0 1 1 1 1 ELMO/CED-12 family PH_12 PF16457.5 OAG45694.1 - 1.2e-33 116.5 0.0 3.8e-33 114.9 0.0 1.9 2 1 0 2 2 2 1 Pleckstrin homology domain DUF3361 PF11841.8 OAG45694.1 - 0.026 14.5 0.4 0.055 13.4 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3361) RPN1_RPN2_N PF17781.1 OAG45694.1 - 0.12 11.7 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 RPN1/RPN2 N-terminal domain MFS_1 PF07690.16 OAG45695.1 - 2.9e-20 72.5 32.4 2.9e-20 72.5 32.4 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAG45695.1 - 2.5e-15 56.3 25.3 3.5e-15 55.8 25.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG45696.1 - 2.8e-38 131.7 27.0 3.8e-38 131.3 27.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Neurensin PF14927.6 OAG45696.1 - 0.7 9.6 4.9 1.7 8.4 0.0 3.1 3 0 0 3 3 3 0 Neurensin AMP-binding PF00501.28 OAG45698.1 - 2.3e-212 705.2 0.0 1.2e-75 254.7 0.0 3.3 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.20 OAG45698.1 - 1.3e-186 620.8 0.0 1.2e-36 126.4 0.0 9.4 7 2 1 8 8 8 8 Condensation domain PP-binding PF00550.25 OAG45698.1 - 2.2e-55 184.9 4.1 2.5e-11 43.7 0.0 6.7 6 0 0 6 6 6 6 Phosphopantetheine attachment site AMP-binding_C PF13193.6 OAG45698.1 - 7.6e-16 58.9 0.2 4.3e-07 30.8 0.0 4.3 4 0 0 4 4 4 3 AMP-binding enzyme C-terminal domain Ribos_L4_asso_C PF14374.6 OAG45698.1 - 0.084 12.9 0.0 0.3 11.2 0.0 1.9 1 0 0 1 1 1 0 60S ribosomal protein L4 C-terminal domain K_oxygenase PF13434.6 OAG45699.1 - 1.9e-113 379.1 0.0 2.3e-113 378.8 0.0 1.0 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 OAG45699.1 - 6.9e-07 28.8 0.0 0.00011 21.5 0.0 2.3 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAG45699.1 - 2.1e-06 27.8 0.1 0.026 14.5 0.0 3.5 3 1 0 3 3 3 3 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 OAG45699.1 - 9.4e-05 21.8 0.0 0.03 13.6 0.0 2.9 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase AAA PF00004.29 OAG45700.1 - 1.4e-52 177.6 0.0 4.6e-43 146.8 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OAG45700.1 - 1.8e-07 30.8 0.7 1.8e-05 24.4 0.0 2.7 2 0 0 2 2 2 1 AAA+ lid domain AAA_16 PF13191.6 OAG45700.1 - 0.00011 22.6 0.1 0.025 14.9 0.0 3.2 3 0 0 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 OAG45700.1 - 0.00026 20.8 0.0 0.00065 19.5 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 OAG45700.1 - 0.0011 19.3 0.0 0.017 15.5 0.0 2.5 2 0 0 2 2 2 1 RNA helicase Parvo_NS1 PF01057.17 OAG45700.1 - 0.0012 18.0 0.0 0.0024 17.0 0.0 1.4 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_2 PF07724.14 OAG45700.1 - 0.0027 17.9 0.0 0.0089 16.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 OAG45700.1 - 0.0027 17.5 0.0 0.0083 15.9 0.0 1.7 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_22 PF13401.6 OAG45700.1 - 0.0071 16.6 1.0 0.056 13.7 0.0 2.9 4 1 0 4 4 3 1 AAA domain AAA_5 PF07728.14 OAG45700.1 - 0.0081 16.2 0.0 0.14 12.2 0.0 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 OAG45700.1 - 0.0086 15.3 0.0 0.015 14.5 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain ATPase PF06745.13 OAG45700.1 - 0.013 14.8 0.0 0.028 13.8 0.0 1.4 1 0 0 1 1 1 0 KaiC Mg_chelatase PF01078.21 OAG45700.1 - 0.028 13.8 0.0 0.056 12.8 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 OAG45700.1 - 0.044 13.4 0.2 0.19 11.3 0.0 2.1 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.6 OAG45700.1 - 0.065 13.8 0.0 0.14 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 OAG45700.1 - 0.073 12.5 0.0 0.19 11.2 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_7 PF12775.7 OAG45700.1 - 0.092 12.3 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_14 PF13173.6 OAG45700.1 - 0.094 12.8 0.0 2 8.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 OAG45700.1 - 0.11 12.5 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 OAG45700.1 - 0.13 12.5 0.0 0.32 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 OAG45700.1 - 0.13 12.4 0.0 0.46 10.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain Dpy-30 PF05186.13 OAG45702.1 - 0.0022 17.6 0.0 0.005 16.5 0.0 1.5 1 1 0 1 1 1 1 Dpy-30 motif Ribosomal_S13_N PF08069.12 OAG45703.1 - 2.4e-28 97.9 0.1 3.7e-28 97.3 0.1 1.3 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 OAG45703.1 - 2.9e-15 56.3 0.3 4e-15 55.8 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.18 OAG45703.1 - 0.06 13.3 0.1 0.14 12.1 0.0 1.6 2 0 0 2 2 2 0 'Paired box' domain zf-HC5HC2H_2 PF13832.6 OAG45704.1 - 3.6e-33 114.0 1.7 3.6e-33 114.0 1.7 2.4 2 0 0 2 2 2 1 PHD-zinc-finger like domain EPL1 PF10513.9 OAG45704.1 - 3.8e-30 105.3 0.0 1.8e-29 103.2 0.0 2.2 2 0 0 2 2 2 1 Enhancer of polycomb-like zf-HC5HC2H PF13771.6 OAG45704.1 - 7.8e-26 90.2 0.5 7.8e-26 90.2 0.5 3.0 2 1 1 3 3 3 1 PHD-like zinc-binding domain PHD_2 PF13831.6 OAG45704.1 - 1.7e-14 53.0 2.9 5.2e-14 51.5 2.9 1.9 1 0 0 1 1 1 1 PHD-finger PHD PF00628.29 OAG45704.1 - 1.9e-10 40.5 19.6 9.2e-09 35.1 9.6 2.7 2 0 0 2 2 2 2 PHD-finger zf-PHD-like PF15446.6 OAG45704.1 - 0.0082 15.8 2.1 0.025 14.2 2.1 1.8 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain Prok-RING_1 PF14446.6 OAG45704.1 - 0.033 14.1 14.2 1.1 9.2 7.0 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Spt5_N PF11942.8 OAG45704.1 - 5.3 8.1 7.3 52 4.9 1.3 3.5 3 0 0 3 3 3 0 Spt5 transcription elongation factor, acidic N-terminal RRM_1 PF00076.22 OAG45705.1 - 3.5e-20 71.6 0.0 5.1e-20 71.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OAG45705.1 - 0.00074 19.1 0.0 0.0011 18.6 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Myb_DNA-bind_6 PF13921.6 OAG45707.1 - 2.4e-05 24.5 0.5 5.8e-05 23.3 0.5 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 OAG45707.1 - 9.4e-05 22.5 0.4 0.00028 21.0 0.1 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain HEPN-like_int PF18867.1 OAG45707.1 - 0.078 12.8 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 HEPN-like integron domain Mito_carr PF00153.27 OAG45708.1 - 1.7e-72 239.4 0.0 6.6e-25 86.9 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_6 PF13405.6 OAG45708.1 - 1.8e-17 61.7 0.8 1.5e-07 30.8 0.1 5.7 6 0 0 6 6 6 2 EF-hand domain EF-hand_7 PF13499.6 OAG45708.1 - 3.1e-17 62.8 6.7 4.5e-09 36.6 2.0 4.6 3 2 2 5 5 5 3 EF-hand domain pair EF-hand_1 PF00036.32 OAG45708.1 - 8.4e-14 50.0 3.5 4.2e-07 29.0 0.1 5.6 6 0 0 6 6 6 2 EF hand EF-hand_5 PF13202.6 OAG45708.1 - 2.2e-07 30.0 3.9 0.00045 19.6 0.1 4.9 5 0 0 5 5 5 1 EF hand EF-hand_8 PF13833.6 OAG45708.1 - 2.2e-05 24.2 0.5 3.6 7.5 0.0 4.7 4 1 0 4 4 4 2 EF-hand domain pair EF-hand_9 PF14658.6 OAG45708.1 - 5.5e-05 23.4 0.0 0.29 11.5 0.0 3.3 3 0 0 3 3 3 2 EF-hand domain VRR_NUC PF08774.11 OAG45709.1 - 6.4e-18 64.8 0.0 1.6e-17 63.5 0.0 1.7 1 0 0 1 1 1 1 VRR-NUC domain DUF4701 PF15773.5 OAG45709.1 - 0.04 12.9 8.9 0.18 10.8 0.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4701) HTH_1 PF00126.27 OAG45709.1 - 0.4 10.7 2.4 34 4.5 0.1 3.5 4 0 0 4 4 4 0 Bacterial regulatory helix-turn-helix protein, lysR family Peptidase_S10 PF00450.22 OAG45710.1 - 7.5e-72 243.0 0.0 1.1e-71 242.5 0.0 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase AA_permease_2 PF13520.6 OAG45711.1 - 6.2e-65 219.7 45.4 7.8e-65 219.4 45.4 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAG45711.1 - 1.1e-13 50.6 35.7 1.5e-13 50.1 35.7 1.2 1 0 0 1 1 1 1 Amino acid permease Abhydro_lipase PF04083.16 OAG45712.1 - 5.2e-19 67.6 0.0 1.3e-18 66.4 0.0 1.7 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 OAG45712.1 - 6.7e-07 29.2 0.0 1.5e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAG45712.1 - 2.2e-05 23.9 0.0 4.3e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 OAG45712.1 - 0.16 10.8 0.0 0.49 9.3 0.0 1.7 2 0 0 2 2 2 0 Chlorophyllase enzyme LSM PF01423.22 OAG45713.1 - 7.4e-17 60.8 0.4 1.1e-16 60.3 0.4 1.2 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 OAG45713.1 - 0.11 12.1 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Hfq protein DRMBL PF07522.14 OAG45714.1 - 7e-35 119.5 0.0 1.4e-34 118.6 0.0 1.5 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 OAG45714.1 - 0.0026 17.3 0.0 0.005 16.4 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Mito_carr PF00153.27 OAG45715.1 - 1e-59 198.4 0.8 2.1e-20 72.4 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DMAP_binding PF06464.11 OAG45716.1 - 0.35 11.7 1.8 0.47 11.3 0.6 1.8 2 0 0 2 2 2 0 DMAP1-binding Domain DSHCT PF08148.12 OAG45719.1 - 0.065 12.9 0.0 0.091 12.4 0.0 1.2 1 0 0 1 1 1 0 DSHCT (NUC185) domain Sugar_tr PF00083.24 OAG45721.1 - 3e-80 270.3 17.6 3.5e-80 270.1 17.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAG45721.1 - 2.8e-17 62.7 54.5 1.5e-10 40.6 4.1 2.3 1 1 2 3 3 3 3 Major Facilitator Superfamily MFS_1_like PF12832.7 OAG45721.1 - 0.0003 19.8 3.7 0.0003 19.8 3.7 1.7 2 0 0 2 2 2 1 MFS_1 like family Beta-APP PF03494.13 OAG45721.1 - 0.38 10.6 2.0 0.91 9.4 2.0 1.6 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) Cyclin PF08613.11 OAG45722.1 - 6.3e-38 130.7 0.0 9.4e-38 130.1 0.0 1.4 1 1 0 1 1 1 1 Cyclin Ead_Ea22 PF13935.6 OAG45723.1 - 0.0024 18.6 2.8 0.004 17.8 2.8 1.5 1 0 0 1 1 1 1 Ead/Ea22-like protein A_deaminase PF00962.22 OAG45725.1 - 5.8e-119 397.3 0.1 8.1e-119 396.8 0.1 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase Peptidase_S41 PF03572.18 OAG45726.1 - 7.5e-09 35.4 0.1 3.3e-08 33.3 0.1 1.9 1 1 0 1 1 1 1 Peptidase family S41 Mucin PF01456.17 OAG45726.1 - 3.3 7.7 15.8 12 5.9 9.0 2.5 2 0 0 2 2 2 0 Mucin-like glycoprotein SAS4 PF15460.6 OAG45728.1 - 6.3e-30 103.2 7.5 1.3e-29 102.2 7.5 1.6 1 0 0 1 1 1 1 Something about silencing, SAS, complex subunit 4 P_proprotein PF01483.20 OAG45729.1 - 1.5e-26 92.2 0.3 2.7e-26 91.4 0.3 1.5 1 0 0 1 1 1 1 Proprotein convertase P-domain Peptidase_S8 PF00082.22 OAG45729.1 - 1.8e-26 93.1 2.2 1.1e-25 90.6 2.2 2.0 1 1 0 1 1 1 1 Subtilase family S8_pro-domain PF16470.5 OAG45729.1 - 0.00018 22.2 2.9 0.0016 19.2 2.9 2.4 1 1 0 1 1 1 1 Peptidase S8 pro-domain DUF2235 PF09994.9 OAG45730.1 - 1.5e-66 224.7 0.0 2.5e-66 224.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) PhoD PF09423.10 OAG45730.1 - 6.9e-08 31.9 0.0 5.7e-07 28.9 0.0 2.0 1 1 0 1 1 1 1 PhoD-like phosphatase Spt5_N PF11942.8 OAG45731.1 - 0.028 15.4 3.1 0.095 13.7 3.1 1.9 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal Trypan_glycop PF00913.19 OAG45731.1 - 0.051 12.8 0.0 0.094 12.0 0.0 1.3 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein (A-type) DUF5084 PF16894.5 OAG45731.1 - 0.085 13.3 1.2 0.15 12.5 1.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5084) CorA PF01544.18 OAG45731.1 - 0.12 11.7 1.1 2.5 7.3 0.3 2.3 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein 2OG-FeII_Oxy_2 PF13532.6 OAG45732.1 - 1.7e-26 93.6 0.0 2e-26 93.4 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily SPATA6 PF14909.6 OAG45732.1 - 0.079 13.1 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 Spermatogenesis-assoc protein 6 Met_10 PF02475.16 OAG45733.1 - 6.2e-64 215.4 0.0 9.6e-64 214.8 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Cupin_2 PF07883.11 OAG45733.1 - 3.3e-06 26.7 0.6 6.9e-06 25.7 0.6 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 OAG45733.1 - 3.1e-05 23.6 0.0 8.5e-05 22.2 0.0 1.7 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.12 OAG45733.1 - 0.005 16.5 0.0 0.013 15.1 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_6 PF12852.7 OAG45733.1 - 0.065 13.0 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Cupin ABC_transp_aux PF09822.9 OAG45733.1 - 0.12 11.9 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 ABC-type uncharacterized transport system MethyltransfD12 PF02086.15 OAG45733.1 - 0.12 12.1 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase RNA_pol_Rpb4 PF03874.16 OAG45735.1 - 2.3e-15 57.0 0.1 3.3e-15 56.5 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb4 PEP_hydrolase PF09370.10 OAG45737.1 - 8e-135 448.2 0.3 9e-135 448.0 0.3 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate hydrolase-like NMO PF03060.15 OAG45737.1 - 6.2e-05 22.5 0.0 8.5e-05 22.1 0.0 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase DUF4287 PF14117.6 OAG45737.1 - 0.18 12.0 0.0 1.3 9.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4287) UPF0261 PF06792.11 OAG45738.1 - 3e-158 527.0 1.6 3.4e-158 526.8 1.6 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0261) Pkinase PF00069.25 OAG45739.1 - 3.3e-45 154.5 0.0 4.7e-45 154.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAG45739.1 - 9.7e-18 64.4 0.0 1.5e-17 63.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAG45739.1 - 0.0015 17.9 0.0 0.0029 17.0 0.0 1.4 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.22 OAG45739.1 - 0.0031 17.1 0.3 0.0055 16.3 0.3 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 OAG45739.1 - 0.018 14.4 0.1 0.032 13.6 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OAG45739.1 - 0.041 13.8 0.0 0.57 10.1 0.0 2.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OAG45739.1 - 0.15 10.8 0.0 0.43 9.3 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase Choline_kinase PF01633.20 OAG45739.1 - 0.22 11.1 0.4 0.34 10.5 0.4 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase PX PF00787.24 OAG45740.1 - 9.8e-21 73.9 0.0 1.4e-20 73.3 0.0 1.1 1 0 0 1 1 1 1 PX domain DUF1708 PF08101.11 OAG45741.1 - 1.5e-163 545.0 0.0 2e-163 544.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) SRF-TF PF00319.18 OAG45742.1 - 2.3e-24 84.6 0.3 3.4e-24 84.1 0.3 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) ABC_membrane PF00664.23 OAG45743.1 - 6.5e-91 304.8 39.4 4e-46 157.9 15.6 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 OAG45743.1 - 2.3e-69 232.2 0.0 1.3e-33 116.4 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 OAG45743.1 - 2e-13 50.3 0.0 0.00013 21.5 0.0 3.9 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 OAG45743.1 - 2.2e-09 36.7 0.6 0.0047 15.8 0.0 3.9 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_16 PF13191.6 OAG45743.1 - 1.1e-08 35.6 1.8 0.00076 19.9 0.1 2.8 2 1 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 OAG45743.1 - 4.6e-08 33.1 0.0 0.0097 15.8 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 OAG45743.1 - 7.6e-08 32.7 0.5 0.019 15.2 0.1 3.8 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.6 OAG45743.1 - 3.8e-07 29.7 0.3 0.025 14.3 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.6 OAG45743.1 - 1.9e-06 27.6 0.0 0.024 14.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.6 OAG45743.1 - 4.4e-06 26.7 0.3 4 7.1 0.0 4.3 3 1 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_28 PF13521.6 OAG45743.1 - 0.00012 22.3 0.1 0.75 10.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 OAG45743.1 - 0.0003 20.6 0.0 0.58 9.8 0.0 2.8 3 0 0 3 3 3 2 AAA ATPase domain AAA_5 PF07728.14 OAG45743.1 - 0.00033 20.7 0.2 3 7.8 0.0 3.8 4 0 0 4 4 4 2 AAA domain (dynein-related subfamily) Dala_Dala_lig_N PF01820.21 OAG45743.1 - 0.00033 21.1 0.0 0.22 12.0 0.0 2.7 2 0 0 2 2 2 1 D-ala D-ala ligase N-terminus AAA_33 PF13671.6 OAG45743.1 - 0.0024 18.0 0.0 3.3 7.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.6 OAG45743.1 - 0.0029 17.8 5.5 0.81 10.0 0.7 4.3 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 OAG45743.1 - 0.0046 16.7 0.4 6.6 6.4 0.0 3.8 3 1 0 3 3 3 0 AAA domain G-alpha PF00503.20 OAG45743.1 - 0.0092 15.2 0.0 1.2 8.2 0.0 2.4 2 0 0 2 2 2 1 G-protein alpha subunit MMR_HSR1 PF01926.23 OAG45743.1 - 0.018 15.1 0.0 13 6.0 0.0 3.3 3 0 0 3 3 2 0 50S ribosome-binding GTPase RNA_helicase PF00910.22 OAG45743.1 - 0.019 15.4 0.0 9.3 6.7 0.0 2.7 2 0 0 2 2 2 0 RNA helicase NACHT PF05729.12 OAG45743.1 - 0.042 13.8 0.3 8.1 6.3 0.1 2.8 2 0 0 2 2 2 0 NACHT domain Rad17 PF03215.15 OAG45743.1 - 0.05 13.5 0.1 12 5.8 0.0 2.5 2 0 0 2 2 2 0 Rad17 P-loop domain Zeta_toxin PF06414.12 OAG45743.1 - 0.05 12.9 0.0 14 4.9 0.0 2.7 2 0 0 2 2 2 0 Zeta toxin AAA_18 PF13238.6 OAG45743.1 - 0.056 14.0 0.0 15 6.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 OAG45743.1 - 0.057 13.9 0.1 14 6.1 0.1 2.4 2 0 0 2 2 2 0 AAA domain tRNA_lig_kinase PF08303.11 OAG45743.1 - 0.07 13.2 0.0 1.4 9.0 0.0 2.4 2 0 0 2 2 2 0 tRNA ligase kinase domain DUF815 PF05673.13 OAG45743.1 - 0.073 12.2 0.0 6.5 5.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) ATP-synt_ab PF00006.25 OAG45743.1 - 0.08 12.6 0.0 4.2 6.9 0.0 2.6 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_7 PF12775.7 OAG45743.1 - 0.096 12.2 0.0 15 5.0 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_14 PF13173.6 OAG45743.1 - 0.1 12.6 0.0 18 5.3 0.0 3.5 4 0 0 4 4 4 0 AAA domain DUF87 PF01935.17 OAG45743.1 - 0.11 12.5 0.2 14 5.7 0.1 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain AAA PF00004.29 OAG45743.1 - 0.2 12.1 2.5 1e+02 3.3 0.6 4.3 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) GFO_IDH_MocA PF01408.22 OAG45744.1 - 1.1e-16 61.7 0.0 2e-16 60.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.24 OAG45744.1 - 0.022 15.2 0.0 0.062 13.7 0.0 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_3 PF03447.16 OAG45744.1 - 0.08 13.6 0.4 0.47 11.1 0.1 2.1 2 0 0 2 2 2 0 Homoserine dehydrogenase, NAD binding domain Aldedh PF00171.22 OAG45745.1 - 8.2e-147 489.4 0.0 9.2e-147 489.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF2188 PF09954.9 OAG45745.1 - 0.065 13.4 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2188) # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Fonsecaea_monophora-ASM164247v1/GCA_001642475.1_ASM164247v1_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Fonsecaea_monophora-ASM164247v1/GCA_001642475.1_ASM164247v1_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Fonsecaea_monophora-ASM164247v1/GCA_001642475.1_ASM164247v1_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Fonsecaea_monophora-ASM164247v1/GCA_001642475.1_ASM164247v1_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Sun Mar 24 20:51:27 2019 # [ok]