# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- TPR_10 PF13374.6 OAP53696.1 - 7.6e-17 60.6 1.5 3.8e-09 36.1 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 OAP53696.1 - 3.7e-14 52.8 2.7 5.6e-10 39.4 0.4 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat Abhydrolase_6 PF12697.7 OAP53696.1 - 0.00028 21.6 0.6 0.00049 20.8 0.6 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.14 OAP53696.1 - 0.00097 18.7 0.0 0.002 17.7 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) LCAT PF02450.15 OAP53696.1 - 0.0024 17.1 0.0 0.0038 16.5 0.0 1.5 2 0 0 2 2 2 1 Lecithin:cholesterol acyltransferase Hydrolase_4 PF12146.8 OAP53696.1 - 0.0038 16.5 0.0 0.0063 15.8 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 OAP53696.1 - 0.0057 16.4 0.0 0.01 15.6 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein DUF726 PF05277.12 OAP53696.1 - 0.17 10.8 0.0 0.25 10.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF726) DUF1315 PF07023.12 OAP53697.1 - 0.16 12.0 0.1 0.36 10.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1315) GSCFA PF08885.11 OAP53697.1 - 0.19 11.3 0.0 0.32 10.6 0.0 1.3 1 0 0 1 1 1 0 GSCFA family DNA_pol_phi PF04931.13 OAP53698.1 - 3.9 5.5 9.5 4.7 5.2 9.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi Elong-fact-P_C PF09285.11 OAP53700.1 - 0.068 12.9 0.4 0.23 11.2 0.0 2.0 2 0 0 2 2 2 0 Elongation factor P, C-terminal Uma2 PF05685.12 OAP53700.1 - 0.088 12.3 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Putative restriction endonuclease Methyltransf_23 PF13489.6 OAP53704.1 - 6.8e-11 42.3 0.0 7.3e-11 42.2 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAP53704.1 - 0.0064 16.3 0.0 0.0092 15.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAP53704.1 - 0.0099 16.6 0.0 0.018 15.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAP53704.1 - 0.025 15.2 0.0 0.042 14.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 OAP53704.1 - 0.09 13.5 0.0 0.15 12.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain CheR PF01739.18 OAP53704.1 - 0.13 11.7 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Peptidase_A4 PF01828.17 OAP53707.1 - 2e-34 118.9 5.9 1.1e-18 67.4 0.6 2.2 1 1 1 2 2 2 2 Peptidase A4 family DUF3435 PF11917.8 OAP53708.1 - 7.5e-10 38.3 0.1 1.3e-09 37.5 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) Cyclin_N PF00134.23 OAP53709.1 - 5.5e-19 68.2 0.0 7.5e-19 67.7 0.0 1.1 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF3187 PF11383.8 OAP53711.1 - 0.034 13.3 0.0 0.05 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3187) Peptidase_S8 PF00082.22 OAP53711.1 - 0.039 13.2 0.0 0.045 13.0 0.0 1.2 1 0 0 1 1 1 0 Subtilase family DUF3328 PF11807.8 OAP53713.1 - 1e-36 126.8 0.0 1.2e-36 126.5 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) AA_permease_2 PF13520.6 OAP53714.1 - 4.7e-53 180.5 40.5 5.3e-53 180.4 40.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAP53714.1 - 7.8e-21 74.2 35.6 1.1e-20 73.8 35.6 1.1 1 0 0 1 1 1 1 Amino acid permease Abhydrolase_3 PF07859.13 OAP53715.1 - 5.3e-56 189.8 0.2 6.9e-56 189.4 0.2 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 OAP53715.1 - 3.2e-08 32.9 0.2 1.3e-07 30.9 0.2 1.8 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 OAP53715.1 - 2.4e-06 27.2 0.0 6.8e-06 25.7 0.0 1.7 1 1 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 OAP53715.1 - 2.5e-05 23.9 0.0 0.0031 17.1 0.0 2.5 2 0 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 OAP53715.1 - 0.00014 22.5 3.1 0.00027 21.6 3.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAP53715.1 - 0.00024 20.5 0.3 0.0049 16.2 0.3 2.6 1 1 1 2 2 2 1 Serine aminopeptidase, S33 AXE1 PF05448.12 OAP53715.1 - 0.0019 16.9 0.0 0.003 16.3 0.0 1.2 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Say1_Mug180 PF10340.9 OAP53715.1 - 0.003 16.5 0.0 0.0041 16.0 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Esterase_phd PF10503.9 OAP53715.1 - 0.04 13.4 0.0 0.11 12.0 0.0 1.7 1 0 0 1 1 1 0 Esterase PHB depolymerase Aldedh PF00171.22 OAP53716.1 - 1.2e-152 508.7 0.0 1.3e-152 508.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 OAP53716.1 - 0.014 14.4 0.2 0.075 12.1 0.2 1.9 1 1 0 1 1 1 0 Acyl-CoA reductase (LuxC) FAD_binding_2 PF00890.24 OAP53717.1 - 5.3e-35 121.3 1.3 1.1e-33 117.0 1.3 2.0 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 OAP53717.1 - 6.9e-05 22.4 0.0 6.9e-05 22.4 0.0 1.9 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAP53717.1 - 0.00087 18.6 0.4 1.1 8.4 0.2 2.7 1 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAP53717.1 - 0.045 12.4 6.3 0.25 10.0 0.4 3.1 3 0 0 3 3 3 0 HI0933-like protein Forkhead PF00250.18 OAP53717.1 - 0.077 13.3 0.0 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 Forkhead domain GIDA PF01134.22 OAP53717.1 - 3 6.8 6.7 0.63 9.1 0.8 2.5 3 0 0 3 3 3 0 Glucose inhibited division protein A Mito_carr PF00153.27 OAP53718.1 - 3.1e-50 168.0 8.2 9.9e-17 60.7 0.4 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Phage_fiber_2 PF03406.13 OAP53718.1 - 0.79 9.3 0.0 0.79 9.3 0.0 2.9 3 0 0 3 3 3 0 Phage tail fibre repeat 4HBT_3 PF13622.6 OAP53721.1 - 5.1e-65 220.2 2.9 6.2e-65 219.9 2.9 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 OAP53721.1 - 3.6e-19 68.9 0.1 1e-10 41.6 0.0 4.0 2 2 0 2 2 2 2 Acyl-CoA thioesterase UNC-93 PF05978.16 OAP53722.1 - 2.9e-07 30.3 4.9 2.9e-07 30.3 4.9 2.6 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 OAP53722.1 - 0.0005 19.1 33.3 0.0005 19.1 33.3 2.7 1 1 0 2 2 2 1 Major Facilitator Superfamily Ribonuc_L-PSP PF01042.21 OAP53723.1 - 2.4e-18 66.3 0.0 2.9e-18 66.0 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP DUF1967 PF09269.11 OAP53723.1 - 0.15 12.0 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1967) Amidase PF01425.21 OAP53724.1 - 9.6e-81 272.0 0.0 1.3e-80 271.6 0.0 1.2 1 0 0 1 1 1 1 Amidase TAL_FSA PF00923.19 OAP53725.1 - 7e-32 110.9 0.0 8.7e-32 110.6 0.0 1.1 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase Glyoxalase PF00903.25 OAP53726.1 - 2.1e-07 31.2 0.0 3.4e-07 30.5 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 OAP53726.1 - 3.7e-07 30.4 0.0 5.6e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 OAP53726.1 - 2e-05 25.3 0.0 8.1e-05 23.4 0.0 1.9 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_3 PF13468.6 OAP53726.1 - 0.00078 19.6 0.0 0.018 15.1 0.0 2.0 2 0 0 2 2 2 1 Glyoxalase-like domain Amino_oxidase PF01593.24 OAP53727.1 - 4.1e-52 178.0 0.0 5.3e-52 177.6 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OAP53727.1 - 5.2e-12 45.8 0.2 1.2e-11 44.7 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 OAP53727.1 - 4.1e-07 29.4 0.5 6.4e-07 28.8 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 OAP53727.1 - 6.9e-07 28.7 0.1 1.1e-06 28.1 0.1 1.2 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 OAP53727.1 - 2.3e-05 23.9 0.5 3.4e-05 23.4 0.5 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 OAP53727.1 - 0.00018 20.9 0.3 0.0069 15.7 0.4 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAP53727.1 - 0.00046 19.9 0.6 0.002 17.8 0.8 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 OAP53727.1 - 0.00096 18.5 0.5 0.0015 17.9 0.5 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 OAP53727.1 - 0.0021 16.8 0.1 0.003 16.3 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.22 OAP53727.1 - 0.0035 16.5 0.1 0.0058 15.8 0.1 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 OAP53727.1 - 0.0058 15.7 0.3 0.0094 15.0 0.3 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 OAP53727.1 - 0.027 13.7 0.0 0.044 13.0 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAP53727.1 - 0.12 13.0 0.1 0.27 11.8 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase adh_short PF00106.25 OAP53728.1 - 7.3e-44 149.6 0.0 9.5e-44 149.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP53728.1 - 2.2e-29 102.7 0.0 2.7e-29 102.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP53728.1 - 3.4e-05 23.9 0.0 5.3e-05 23.2 0.0 1.3 1 1 0 1 1 1 1 KR domain Fungal_trans PF04082.18 OAP53729.1 - 3.1e-22 78.9 0.1 5.9e-22 78.0 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP53729.1 - 7.7e-09 35.5 12.9 1.6e-08 34.5 12.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Transglut_core PF01841.19 OAP53729.1 - 0.12 12.8 0.0 0.29 11.6 0.0 1.7 1 0 0 1 1 1 0 Transglutaminase-like superfamily Peptidase_C14 PF00656.22 OAP53732.1 - 8.7e-17 61.9 0.0 1.3e-16 61.3 0.0 1.2 1 0 0 1 1 1 1 Caspase domain FlgT_C PF16538.5 OAP53732.1 - 0.025 15.1 0.0 0.06 13.9 0.0 1.7 1 0 0 1 1 1 0 Flagellar assembly protein T, C-terminal domain PYNP_C PF07831.13 OAP53732.1 - 0.18 11.5 0.0 0.36 10.5 0.0 1.4 1 0 0 1 1 1 0 Pyrimidine nucleoside phosphorylase C-terminal domain CHAT PF12770.7 OAP53733.1 - 2.1e-35 122.5 0.2 3.5e-35 121.8 0.2 1.4 1 0 0 1 1 1 1 CHAT domain TPR_10 PF13374.6 OAP53733.1 - 6.8e-31 105.3 41.4 5.9e-06 26.0 0.1 13.1 13 1 0 14 14 14 7 Tetratricopeptide repeat TPR_2 PF07719.17 OAP53733.1 - 0.00014 21.7 15.8 3.3 8.1 0.1 8.9 10 0 0 10 10 10 2 Tetratricopeptide repeat DUF627 PF04781.12 OAP53733.1 - 0.0014 18.6 0.1 0.039 14.0 0.0 3.3 1 1 2 3 3 3 1 Protein of unknown function (DUF627) TPR_12 PF13424.6 OAP53733.1 - 0.0059 16.9 23.3 3.3 8.1 0.0 8.5 8 3 3 11 11 11 2 Tetratricopeptide repeat TPR_1 PF00515.28 OAP53733.1 - 0.075 12.9 5.8 34 4.5 0.0 6.2 7 0 0 7 7 7 0 Tetratricopeptide repeat Imm53 PF15580.6 OAP53733.1 - 0.084 12.6 0.1 3.7 7.3 0.0 3.5 3 1 1 4 4 4 0 Immunity protein 53 RPN6_N PF18055.1 OAP53733.1 - 0.085 13.2 2.4 1.2 9.5 0.0 3.8 4 1 1 5 5 5 0 26S proteasome regulatory subunit RPN6 N-terminal domain TPR_8 PF13181.6 OAP53733.1 - 0.091 13.0 10.2 8.7 6.8 0.1 7.7 11 0 0 11 11 7 0 Tetratricopeptide repeat DALR_1 PF05746.15 OAP53733.1 - 0.25 11.5 3.4 10 6.4 0.1 4.1 4 1 0 4 4 4 0 DALR anticodon binding domain TPR_16 PF13432.6 OAP53733.1 - 9.5 7.0 12.1 33 5.2 2.9 5.5 4 2 2 6 6 6 0 Tetratricopeptide repeat HET PF06985.11 OAP53734.1 - 4.5e-31 108.2 0.5 1.9e-30 106.1 0.3 2.2 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) CHAT PF12770.7 OAP53734.1 - 3e-29 102.3 0.0 7.9e-29 101.0 0.0 1.7 1 0 0 1 1 1 1 CHAT domain Peptidase_C14 PF00656.22 OAP53734.1 - 1.4e-14 54.7 0.0 3.7e-14 53.3 0.0 1.7 1 0 0 1 1 1 1 Caspase domain TPR_16 PF13432.6 OAP53734.1 - 0.012 16.3 2.4 0.12 13.0 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Fungal_trans PF04082.18 OAP53737.1 - 4.9e-09 35.6 0.1 1.3e-08 34.2 0.1 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain YPEB PF14620.6 OAP53737.1 - 0.14 11.5 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 YpeB sporulation Beta-lactamase PF00144.24 OAP53738.1 - 1.2e-60 205.5 0.0 1.4e-60 205.3 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase adh_short_C2 PF13561.6 OAP53739.1 - 3.7e-62 209.9 0.6 4.2e-62 209.8 0.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP53739.1 - 1.7e-51 174.4 0.4 2.1e-51 174.2 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAP53739.1 - 1.1e-16 61.3 0.3 1.5e-16 60.9 0.3 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAP53739.1 - 0.0003 20.3 2.0 0.00084 18.9 2.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 OAP53739.1 - 0.018 14.9 0.2 0.03 14.2 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_25 PF13649.6 OAP53739.1 - 0.096 13.4 0.0 0.2 12.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain 3Beta_HSD PF01073.19 OAP53739.1 - 0.11 11.5 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family FMO-like PF00743.19 OAP53740.1 - 9.7e-17 60.6 0.2 2.4e-12 46.1 0.1 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 OAP53740.1 - 7.7e-14 51.6 0.0 9.3e-12 44.8 0.0 2.6 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAP53740.1 - 1.5e-13 50.6 0.0 1.1e-11 44.5 0.0 2.3 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 OAP53740.1 - 9.9e-12 44.7 0.0 1.1e-10 41.3 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAP53740.1 - 1.4e-09 38.0 0.1 1.1e-06 28.8 0.1 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.6 OAP53740.1 - 1.1e-06 29.1 0.0 0.00041 20.8 0.0 2.7 2 1 0 2 2 2 1 Putative NAD(P)-binding Pyr_redox PF00070.27 OAP53740.1 - 1.2e-05 25.8 0.5 0.24 12.0 0.0 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAP53740.1 - 2.8e-05 24.2 0.3 0.23 11.5 0.2 3.8 3 1 0 3 3 3 1 FAD-NAD(P)-binding Shikimate_DH PF01488.20 OAP53740.1 - 0.00018 21.6 0.0 0.0027 17.8 0.0 2.6 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase DAO PF01266.24 OAP53740.1 - 0.00039 20.1 3.1 0.044 13.4 0.6 3.3 3 1 0 4 4 4 1 FAD dependent oxidoreductase HI0933_like PF03486.14 OAP53740.1 - 0.0053 15.5 0.6 0.66 8.6 0.1 2.9 3 0 0 3 3 3 1 HI0933-like protein ApbA PF02558.16 OAP53740.1 - 0.009 15.7 0.5 0.07 12.8 0.0 2.7 3 0 0 3 3 3 1 Ketopantoate reductase PanE/ApbA Lycopene_cycl PF05834.12 OAP53740.1 - 0.014 14.5 0.0 2.6 7.0 0.0 2.7 3 0 0 3 3 3 0 Lycopene cyclase protein 2-Hacid_dh_C PF02826.19 OAP53740.1 - 0.014 14.7 0.0 0.041 13.2 0.0 1.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 OAP53740.1 - 0.017 14.4 0.6 0.73 9.1 0.2 2.7 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 OAP53740.1 - 0.046 12.9 0.1 5.5 6.2 0.0 2.2 2 0 0 2 2 2 0 Thi4 family FAD_binding_2 PF00890.24 OAP53740.1 - 0.052 12.6 0.0 0.1 11.6 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain 3HCDH_N PF02737.18 OAP53740.1 - 0.2 11.6 0.3 2.2 8.2 0.0 2.4 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Abhydrolase_3 PF07859.13 OAP53741.1 - 5.1e-06 26.5 0.0 7.3e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 OAP53741.1 - 0.00017 20.6 0.0 0.00031 19.7 0.0 1.3 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.7 OAP53741.1 - 0.00021 22.0 0.8 0.00042 21.0 0.8 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF1749 PF08538.10 OAP53741.1 - 0.0027 16.9 0.0 0.0044 16.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Say1_Mug180 PF10340.9 OAP53741.1 - 0.0058 15.5 0.0 0.0082 15.0 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Hydrolase_4 PF12146.8 OAP53741.1 - 0.039 13.2 0.0 0.059 12.6 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Cupin_2 PF07883.11 OAP53742.1 - 4.8e-13 48.6 0.2 7.6e-09 35.2 0.1 2.6 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 OAP53742.1 - 0.00015 21.4 0.1 0.19 11.4 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF861) MannoseP_isomer PF01050.18 OAP53742.1 - 0.00035 20.5 0.0 0.089 12.7 0.0 2.2 2 0 0 2 2 2 2 Mannose-6-phosphate isomerase AraC_binding PF02311.19 OAP53742.1 - 0.00097 19.1 0.1 0.005 16.7 0.1 2.0 2 0 0 2 2 2 1 AraC-like ligand binding domain Cupin_1 PF00190.22 OAP53742.1 - 0.035 13.7 0.7 0.77 9.4 0.1 2.5 2 1 1 3 3 3 0 Cupin FdtA PF05523.11 OAP53742.1 - 0.095 12.4 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 WxcM-like, C-terminal Amidohydro_2 PF04909.14 OAP53743.1 - 5e-37 128.3 0.1 6.2e-37 128.0 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase MFS_1 PF07690.16 OAP53744.1 - 2.1e-33 115.7 32.0 2.1e-33 115.7 32.0 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily ADH_N PF08240.12 OAP53745.1 - 0.038 13.9 0.3 0.056 13.3 0.3 1.3 1 1 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain Acetyltransf_1 PF00583.25 OAP53747.1 - 4.4e-07 30.1 0.0 5.9e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OAP53747.1 - 2e-05 24.9 0.0 3.5e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OAP53747.1 - 0.00043 20.2 0.0 0.00064 19.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 OAP53747.1 - 0.0018 18.4 0.0 0.003 17.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 OAP53747.1 - 0.04 14.0 0.0 0.075 13.2 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase FR47 PF08445.10 OAP53747.1 - 0.12 12.3 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein FAM110_C PF14160.6 OAP53747.1 - 0.2 12.7 0.0 0.31 12.1 0.0 1.2 1 0 0 1 1 1 0 Centrosome-associated C terminus DUF2325 PF10087.9 OAP53750.1 - 0.018 15.2 0.0 0.025 14.7 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2325) zf-C3HC4 PF00097.25 OAP53757.1 - 2.1e-07 30.7 5.9 3.6e-07 29.9 5.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OAP53757.1 - 3.5e-07 30.0 4.1 5.9e-07 29.3 4.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAP53757.1 - 4.4e-07 29.8 3.1 8.2e-07 29.0 3.1 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 OAP53757.1 - 3.4e-06 27.3 6.1 8.5e-06 26.0 6.1 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 OAP53757.1 - 5.2e-06 26.2 10.0 6.1e-05 22.8 10.0 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OAP53757.1 - 7.2e-05 22.6 5.6 0.00038 20.3 5.9 2.1 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 OAP53757.1 - 0.00014 21.8 5.9 0.00029 20.8 5.9 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 OAP53757.1 - 0.00032 20.9 6.3 0.0011 19.2 6.3 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 OAP53757.1 - 0.003 17.7 4.0 0.0079 16.3 4.0 1.8 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING Exonuc_VII_L PF02601.15 OAP53757.1 - 0.0056 16.3 1.7 0.0066 16.1 1.7 1.1 1 0 0 1 1 1 1 Exonuclease VII, large subunit DUF4763 PF15960.5 OAP53757.1 - 0.018 14.4 13.2 0.025 13.9 13.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) zf-UDP PF14569.6 OAP53757.1 - 0.021 14.9 2.0 0.048 13.8 2.0 1.5 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-ANAPC11 PF12861.7 OAP53757.1 - 0.029 14.4 1.3 0.058 13.5 1.3 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-4CXXC_R1 PF10497.9 OAP53757.1 - 0.04 14.1 3.6 0.073 13.3 3.4 1.5 1 1 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 FYVE PF01363.21 OAP53757.1 - 0.07 13.3 4.7 0.24 11.5 4.7 1.9 1 1 0 1 1 1 0 FYVE zinc finger UPF0242 PF06785.11 OAP53757.1 - 0.084 13.0 10.8 0.11 12.6 10.8 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF4407 PF14362.6 OAP53757.1 - 0.2 11.0 4.7 0.32 10.3 4.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SOGA PF11365.8 OAP53757.1 - 0.22 12.7 7.0 0.39 11.9 7.0 1.4 1 0 0 1 1 1 0 Protein SOGA Macoilin PF09726.9 OAP53757.1 - 0.34 9.4 10.4 0.47 8.9 10.4 1.2 1 0 0 1 1 1 0 Macoilin family Lectin_N PF03954.14 OAP53757.1 - 0.38 10.5 6.0 0.55 10.0 6.0 1.2 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain Atg14 PF10186.9 OAP53757.1 - 0.39 9.8 8.5 0.56 9.2 8.5 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Spc42p PF11544.8 OAP53757.1 - 0.48 10.5 9.6 0.89 9.6 9.1 1.7 1 1 0 1 1 1 0 Spindle pole body component Spc42p IBR PF01485.21 OAP53757.1 - 0.69 10.2 8.7 1.9 8.8 4.1 2.8 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain zf-RING_4 PF14570.6 OAP53757.1 - 0.73 9.7 7.4 3.5 7.5 7.4 2.0 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain OmpH PF03938.14 OAP53757.1 - 0.8 10.0 11.0 1.2 9.5 11.0 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) CREPT PF16566.5 OAP53757.1 - 1.5 9.0 11.8 18 5.5 0.3 2.2 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour TMPIT PF07851.13 OAP53757.1 - 2.4 7.3 6.2 3 7.0 6.2 1.1 1 0 0 1 1 1 0 TMPIT-like protein Seryl_tRNA_N PF02403.22 OAP53757.1 - 2.7 8.3 12.4 5.8 7.2 12.4 1.5 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain V_ATPase_I PF01496.19 OAP53757.1 - 3.4 5.5 6.9 4 5.2 6.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family KxDL PF10241.9 OAP53757.1 - 4.9 7.5 13.8 3.1 8.1 11.0 1.8 1 1 1 2 2 2 0 Uncharacterized conserved protein Clat_adaptor_s PF01217.20 OAP53759.1 - 0.00029 20.8 0.0 0.00031 20.7 0.0 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF3435 PF11917.8 OAP53763.1 - 1.3e-06 27.6 8.3 4.9e-06 25.7 8.3 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF3435) ABC_membrane PF00664.23 OAP53768.1 - 1.9e-09 37.6 0.1 2.2e-09 37.4 0.1 1.0 1 0 0 1 1 1 1 ABC transporter transmembrane region JmjC PF02373.22 OAP53769.1 - 5.5e-18 65.5 0.0 9.2e-18 64.7 0.0 1.4 1 0 0 1 1 1 1 JmjC domain, hydroxylase zf-IS66 PF13005.7 OAP53769.1 - 0.071 13.5 0.3 16 6.0 0.1 2.3 2 0 0 2 2 2 0 zinc-finger binding domain of transposase IS66 Plasmo_rep PF12135.8 OAP53770.1 - 0.012 15.1 0.9 0.035 13.7 0.9 1.8 1 1 0 1 1 1 0 Plasmodium repeat family Castor_Poll_mid PF06241.12 OAP53770.1 - 0.058 13.4 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Castor and Pollux, part of voltage-gated ion channel Peptidase_C48 PF02902.19 OAP53771.1 - 0.01 15.7 0.1 0.016 15.0 0.1 1.2 1 0 0 1 1 1 0 Ulp1 protease family, C-terminal catalytic domain bZIP_1 PF00170.21 OAP53772.1 - 0.002 18.2 9.4 0.004 17.2 9.4 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 OAP53772.1 - 0.0032 17.5 8.5 0.0061 16.6 8.5 1.4 1 0 0 1 1 1 1 Basic region leucine zipper PLD_C PF12357.8 OAP53773.1 - 0.0086 16.0 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 Phospholipase D C terminal URO-D PF01208.17 OAP53775.1 - 6.3e-14 51.9 0.0 7.2e-14 51.7 0.0 1.1 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) SH3_9 PF14604.6 OAP53776.1 - 3.8e-11 42.7 0.0 5.2e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 OAP53776.1 - 7.3e-08 31.9 0.0 9.9e-08 31.5 0.0 1.2 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 OAP53776.1 - 4.5e-06 26.2 0.0 6.8e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain adh_short PF00106.25 OAP53779.1 - 2.5e-26 92.4 0.0 1e-25 90.4 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP53779.1 - 5e-19 68.8 0.0 2.8e-08 33.6 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP53779.1 - 9.4e-05 22.4 0.1 0.0011 18.9 0.0 2.3 2 1 0 2 2 2 1 KR domain DUF3124 PF11322.8 OAP53779.1 - 0.15 12.2 0.0 0.51 10.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3124) dCMP_cyt_deam_1 PF00383.23 OAP53780.1 - 1e-19 70.3 0.1 1.4e-19 69.8 0.1 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 OAP53780.1 - 1.1e-15 57.6 0.1 1.3e-15 57.3 0.1 1.1 1 0 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 OAP53780.1 - 0.00023 21.3 1.3 0.14 12.2 1.1 2.2 1 1 1 2 2 2 2 Bd3614-like deaminase SNAD4 PF18750.1 OAP53780.1 - 0.0027 17.8 0.0 0.019 15.1 0.0 2.0 2 0 0 2 2 2 1 Secreted Novel AID/APOBEC-like Deaminase 4 NAD1 PF18778.1 OAP53780.1 - 0.0068 16.5 0.1 0.13 12.4 0.0 2.0 1 1 1 2 2 2 1 Novel AID APOBEC clade 1 APOBEC2 PF18772.1 OAP53780.1 - 0.011 15.8 0.0 0.21 11.6 0.0 2.0 1 1 0 1 1 1 0 APOBEC2 NAD2 PF18782.1 OAP53780.1 - 0.042 14.0 0.0 0.12 12.5 0.0 1.7 1 1 0 1 1 1 0 Novel AID APOBEC clade 2 APOBEC_N PF08210.11 OAP53780.1 - 0.046 13.6 0.0 0.16 11.9 0.0 1.8 1 1 0 1 1 1 0 APOBEC-like N-terminal domain URO-D PF01208.17 OAP53781.1 - 1.5e-24 86.8 0.0 1.6e-24 86.7 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) Abhydrolase_3 PF07859.13 OAP53782.1 - 1.3e-13 51.3 0.0 2.8e-08 33.9 0.0 2.0 1 1 1 2 2 2 2 alpha/beta hydrolase fold COG6 PF06419.11 OAP53783.1 - 3.9e-29 101.4 2.6 6e-17 61.1 0.6 2.0 1 1 1 2 2 2 2 Conserved oligomeric complex COG6 Htr2 PF17909.1 OAP53783.1 - 0.027 14.7 1.0 0.036 14.3 0.2 1.6 2 0 0 2 2 2 0 Htr2 transmembrane domain DUF4054 PF13262.6 OAP53783.1 - 0.046 13.7 0.0 0.098 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4054) Redoxin PF08534.10 OAP53784.1 - 3.3e-19 69.1 0.0 4e-19 68.8 0.0 1.0 1 0 0 1 1 1 1 Redoxin Bunya_G2 PF03563.13 OAP53785.1 - 0.16 11.2 0.0 0.21 10.8 0.0 1.1 1 0 0 1 1 1 0 Bunyavirus glycoprotein G2 SBDS_C PF09377.10 OAP53786.1 - 2.6e-06 27.4 0.0 2.6e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 SBDS protein C-terminal domain tRNA-synt_1 PF00133.22 OAP53786.1 - 0.057 11.7 0.0 0.074 11.3 0.0 1.0 1 0 0 1 1 1 0 tRNA synthetases class I (I, L, M and V) TPR_19 PF14559.6 OAP53787.1 - 0.11 13.1 0.0 0.19 12.2 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat Pkinase PF00069.25 OAP53791.1 - 1.2e-30 106.8 0.0 2.5e-30 105.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP53791.1 - 6.4e-13 48.6 0.0 1.5e-12 47.4 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Myb_DNA-binding PF00249.31 OAP53795.1 - 6.9e-07 29.4 3.1 1.3e-06 28.5 3.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OAP53795.1 - 0.016 15.4 2.2 0.038 14.3 2.2 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain Adeno_PIX PF03955.14 OAP53795.1 - 0.039 14.1 0.8 0.093 12.9 0.8 1.6 1 0 0 1 1 1 0 Adenovirus hexon-associated protein (IX) F-box-like PF12937.7 OAP53796.1 - 0.0013 18.5 0.0 0.0025 17.7 0.0 1.5 1 0 0 1 1 1 1 F-box-like DUF641 PF04859.12 OAP53797.1 - 0.025 14.9 0.7 0.041 14.2 0.7 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) SCP-1 PF05483.12 OAP53797.1 - 0.028 12.4 0.2 0.039 12.0 0.2 1.1 1 0 0 1 1 1 0 Synaptonemal complex protein 1 (SCP-1) HAUS-augmin3 PF14932.6 OAP53797.1 - 0.031 13.9 0.7 0.049 13.2 0.7 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Perilipin PF03036.16 OAP53797.1 - 0.053 12.5 1.9 0.078 12.0 1.9 1.1 1 0 0 1 1 1 0 Perilipin family Cortex-I_coil PF09304.10 OAP53797.1 - 0.12 12.6 4.1 0.1 12.8 2.2 1.9 2 1 0 2 2 2 0 Cortexillin I, coiled coil ATG16 PF08614.11 OAP53797.1 - 0.17 12.1 6.3 0.29 11.3 6.3 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DDE_3 PF13358.6 OAP53798.1 - 3.8e-13 49.4 0.3 1.3e-12 47.6 0.1 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease SCAMP PF04144.13 OAP53802.1 - 0.23 11.8 2.3 3.8 7.8 0.1 2.1 2 0 0 2 2 2 0 SCAMP family DUF4405 PF14358.6 OAP53802.1 - 0.27 11.8 4.8 1.6 9.4 0.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4405) NAD_binding_6 PF08030.12 OAP53803.1 - 0.17 12.0 0.0 0.34 11.0 0.0 1.6 1 1 0 1 1 1 0 Ferric reductase NAD binding domain Zn_clus PF00172.18 OAP53805.1 - 0.00093 19.3 8.6 0.00093 19.3 8.6 3.9 4 0 0 4 4 4 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_S64 PF08192.11 OAP53806.1 - 0.0011 17.6 0.3 0.5 8.8 0.0 2.2 2 0 0 2 2 2 2 Peptidase family S64 Trypsin_2 PF13365.6 OAP53806.1 - 0.13 13.2 0.0 3.9 8.4 0.0 2.7 3 0 0 3 3 3 0 Trypsin-like peptidase domain HEPN_STY4199 PF18729.1 OAP53816.1 - 0.049 12.8 0.1 0.061 12.5 0.1 1.1 1 0 0 1 1 1 0 STY4199-like HEPN Asp PF00026.23 OAP53822.1 - 0.00026 20.5 0.0 0.00032 20.2 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Chrome_Resist PF09828.9 OAP53822.1 - 0.047 14.1 0.0 0.052 14.0 0.0 1.2 1 0 0 1 1 1 0 Chromate resistance exported protein DUF3052 PF11253.8 OAP53824.1 - 0.11 12.4 0.4 0.2 11.6 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3052) HTH_Tnp_IS630 PF01710.16 OAP53825.1 - 0.096 12.7 3.2 0.2 11.7 3.2 1.6 1 0 0 1 1 1 0 Transposase Phage_int_SAM_6 PF18644.1 OAP53825.1 - 0.23 11.5 1.8 0.22 11.5 0.2 1.7 2 0 0 2 2 2 0 Phage integrase SAM-like domain Caudo_TAP PF02413.17 OAP53825.1 - 1.8 8.7 10.2 0.47 10.6 6.0 2.2 1 1 1 2 2 2 0 Caudovirales tail fibre assembly protein, lambda gpK RF3_C PF16658.5 OAP53825.1 - 2 8.3 7.8 0.5 10.2 1.6 2.6 1 1 1 2 2 2 0 Class II release factor RF3, C-terminal domain IL15 PF02372.15 OAP53825.1 - 5.7 7.0 7.4 9.6 6.2 0.5 3.3 2 1 1 3 3 3 0 Interleukin 15 TackOD1 PF18551.1 OAP53825.1 - 6.1 6.5 6.9 0.71 9.5 2.0 1.9 2 0 0 2 2 2 0 Thaumarchaeal output domain 1 TrbI_Ftype PF09677.10 OAP53825.1 - 6.7 7.1 8.7 1.8 8.9 2.1 3.1 1 1 2 3 3 3 0 Type-F conjugative transfer system protein (TrbI_Ftype) F-box PF00646.33 OAP53827.1 - 0.011 15.6 0.1 0.38 10.7 0.0 2.6 2 0 0 2 2 2 0 F-box domain APH PF01636.23 OAP53829.1 - 2.4e-13 50.6 0.1 6.7e-13 49.1 0.1 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1732 PF08340.11 OAP53830.1 - 1.7e-09 37.5 0.4 5.1e-09 36.0 0.1 2.0 2 1 0 2 2 2 1 Domain of unknown function (DUF1732) YicC_N PF03755.13 OAP53830.1 - 3.6e-06 27.5 0.0 8.4e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 YicC-like family, N-terminal region Plasmod_dom_1 PF09715.10 OAP53830.1 - 0.19 11.8 0.0 6.9 6.8 0.0 2.3 2 0 0 2 2 2 0 Plasmodium protein of unknown function (Plasmod_dom_1) Apolipoprotein PF01442.18 OAP53830.1 - 0.28 11.0 4.0 0.28 11.0 1.8 1.9 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain CAP_N PF01213.19 OAP53834.1 - 5 6.5 7.2 2.5 7.5 4.0 1.9 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal EAP30 PF04157.16 OAP53839.1 - 0.14 11.4 4.0 0.18 11.0 4.0 1.2 1 0 0 1 1 1 0 EAP30/Vps36 family VIR_N PF15912.5 OAP53839.1 - 3.2 7.3 5.9 4.7 6.7 5.9 1.3 1 0 0 1 1 1 0 Virilizer, N-terminal Abhydrolase_3 PF07859.13 OAP53845.1 - 8.5e-12 45.4 0.0 1.3e-11 44.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold RVT_1 PF00078.27 OAP53851.1 - 3.7e-08 33.2 0.0 6.5e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4939 PF16297.5 OAP53851.1 - 0.00011 22.0 0.0 0.00024 21.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) DUF4965 PF16335.5 OAP53852.1 - 0.22 11.2 0.0 0.43 10.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4965) DUF3138 PF11336.8 OAP53856.1 - 0.24 10.0 0.1 0.33 9.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Eapp_C PF10238.9 OAP53858.1 - 0.017 15.2 0.8 0.03 14.4 0.8 1.3 1 0 0 1 1 1 0 E2F-associated phosphoprotein FancD2 PF14631.6 OAP53862.1 - 0.018 12.5 0.0 0.02 12.3 0.0 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease TGT PF01702.18 OAP53862.1 - 0.028 13.6 0.0 0.04 13.1 0.0 1.2 1 0 0 1 1 1 0 Queuine tRNA-ribosyltransferase Amidase_2 PF01510.25 OAP53866.1 - 0.14 12.6 0.0 0.17 12.3 0.0 1.2 1 0 0 1 1 1 0 N-acetylmuramoyl-L-alanine amidase DUF4077 PF13295.6 OAP53870.1 - 0.057 13.4 0.2 0.084 12.8 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4077) RNA_pol_Rpb2_6 PF00562.28 OAP53871.1 - 0.019 14.0 0.0 0.026 13.6 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 6 Lipoxygenase PF00305.19 OAP53872.1 - 1.2e-19 70.3 0.0 2e-19 69.5 0.0 1.3 1 0 0 1 1 1 1 Lipoxygenase FMO-like PF00743.19 OAP53873.1 - 3.7e-14 52.0 0.1 1.8e-12 46.5 0.0 2.6 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OAP53873.1 - 2e-09 37.5 0.1 5.7e-08 32.9 0.0 2.9 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 OAP53873.1 - 2.6e-09 36.7 0.1 4.2e-07 29.4 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 OAP53873.1 - 7.3e-08 32.0 0.0 4.8e-07 29.3 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAP53873.1 - 2.1e-07 30.9 0.9 0.0099 15.5 0.4 2.5 2 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 OAP53873.1 - 2.6e-05 23.6 0.0 0.00016 21.0 0.0 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAP53873.1 - 0.00068 18.8 0.0 0.0011 18.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 OAP53873.1 - 0.00098 18.5 0.2 0.0025 17.1 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain 2-Hacid_dh_C PF02826.19 OAP53873.1 - 0.0085 15.5 0.0 0.017 14.5 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 OAP53873.1 - 0.024 14.7 0.0 0.65 10.1 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.6 OAP53873.1 - 0.086 12.8 0.7 12 5.9 0.0 3.6 5 0 0 5 5 5 0 FAD-NAD(P)-binding Thi4 PF01946.17 OAP53873.1 - 0.088 12.0 0.1 0.65 9.2 0.0 2.3 3 0 0 3 3 3 0 Thi4 family PepX_C PF08530.10 OAP53873.1 - 0.13 12.1 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain FAD_oxidored PF12831.7 OAP53873.1 - 0.15 11.4 0.1 0.52 9.6 0.1 1.8 1 1 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.22 OAP53873.1 - 0.16 11.0 0.0 13 4.8 0.0 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A MFS_1 PF07690.16 OAP53874.1 - 4.4e-40 137.7 34.3 6.7e-38 130.5 21.9 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 OAP53874.1 - 2.7e-07 29.4 5.0 2.7e-07 29.4 5.0 2.6 2 1 0 2 2 2 1 Transmembrane secretion effector OATP PF03137.20 OAP53874.1 - 0.0041 15.5 4.2 0.34 9.1 0.8 2.4 2 1 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family Cellsynth_D PF03500.13 OAP53874.1 - 0.11 12.3 0.4 0.3 11.0 0.1 1.9 2 0 0 2 2 2 0 Cellulose synthase subunit D JmjC PF02373.22 OAP53875.1 - 2.4e-13 50.5 0.0 4.9e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 JmjC domain, hydroxylase LsmAD PF06741.13 OAP53875.1 - 0.23 12.0 0.4 0.48 11.0 0.4 1.5 1 0 0 1 1 1 0 LsmAD domain bZIP_1 PF00170.21 OAP53876.1 - 2.2e-08 34.1 6.5 3.1e-08 33.6 6.5 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 OAP53876.1 - 0.00096 19.2 7.7 0.0015 18.6 7.7 1.3 1 0 0 1 1 1 1 Basic region leucine zipper PRKG1_interact PF15898.5 OAP53876.1 - 0.0097 16.8 2.1 0.017 16.0 2.1 1.3 1 0 0 1 1 1 1 cGMP-dependent protein kinase interacting domain DUF948 PF06103.11 OAP53877.1 - 0.001 19.2 0.8 0.0022 18.2 0.8 1.4 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF948) FUSC PF04632.12 OAP53877.1 - 0.14 10.7 2.2 0.15 10.6 2.2 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Vps53_N PF04100.12 OAP53877.1 - 0.14 11.1 3.3 0.17 10.8 3.0 1.3 1 1 0 1 1 1 0 Vps53-like, N-terminal SlyX PF04102.12 OAP53877.1 - 0.69 10.6 6.5 0.5 11.0 1.9 2.7 2 1 1 3 3 3 0 SlyX Peptidase_S24 PF00717.23 OAP53880.1 - 0.035 14.1 0.6 4.7 7.2 0.0 2.7 3 0 0 3 3 3 0 Peptidase S24-like DUF3435 PF11917.8 OAP53881.1 - 4.3e-08 32.5 0.0 5.4e-08 32.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) PPR PF01535.20 OAP53881.1 - 0.067 13.5 0.0 0.17 12.2 0.0 1.7 1 0 0 1 1 1 0 PPR repeat DUF3787 PF12655.7 OAP53882.1 - 0.005 16.7 0.0 0.014 15.3 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3787) RT_RNaseH PF17917.1 OAP53883.1 - 2.7e-09 37.2 0.0 5.2e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 OAP53883.1 - 6.6e-08 32.5 0.0 1.4e-07 31.4 0.0 1.6 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Amidase PF01425.21 OAP53885.1 - 1.4e-24 86.9 5.2 1.7e-24 86.6 5.2 1.1 1 0 0 1 1 1 1 Amidase Voltage_CLC PF00654.20 OAP53886.1 - 0.047 12.9 1.7 0.051 12.8 0.5 1.6 2 0 0 2 2 2 0 Voltage gated chloride channel PDR_assoc PF08370.11 OAP53886.1 - 0.19 11.5 0.7 1.4 8.7 0.1 2.5 3 0 0 3 3 3 0 Plant PDR ABC transporter associated KCH PF16944.5 OAP53888.1 - 0.00068 19.5 0.0 0.00088 19.1 0.0 1.0 1 0 0 1 1 1 1 Fungal potassium channel SLC35F PF06027.12 OAP53890.1 - 4.4e-25 88.8 3.8 5.3e-25 88.6 3.8 1.0 1 0 0 1 1 1 1 Solute carrier family 35 HEAT_EZ PF13513.6 OAP53893.1 - 0.064 13.8 0.2 0.17 12.4 0.2 1.8 1 0 0 1 1 1 0 HEAT-like repeat Zn_clus PF00172.18 OAP53894.1 - 0.025 14.7 1.3 0.039 14.1 1.3 1.2 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Pox_F17 PF04767.12 OAP53894.1 - 0.03 14.8 0.1 0.047 14.2 0.1 1.3 1 0 0 1 1 1 0 DNA-binding 11 kDa phosphoprotein FoP_duplication PF13865.6 OAP53897.1 - 1.4e-06 28.8 1.4 2.5e-06 28.0 1.4 1.3 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 AAA_11 PF13086.6 OAP53900.1 - 4.4e-08 33.2 0.0 8.1e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 OAP53900.1 - 0.00011 22.0 0.1 0.00016 21.4 0.1 1.2 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 OAP53900.1 - 0.047 13.0 0.0 0.12 11.7 0.0 1.6 1 1 0 1 1 1 0 KaiC DUF226 PF02890.14 OAP53900.1 - 0.057 13.4 1.4 0.17 11.9 0.1 2.4 3 0 0 3 3 3 0 Borrelia family of unknown function DUF226 Viral_helicase1 PF01443.18 OAP53900.1 - 0.071 12.8 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RT_RNaseH_2 PF17919.1 OAP53902.1 - 7.4e-18 64.4 0.0 1e-17 64.0 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAP53902.1 - 2.2e-11 44.0 0.0 3.3e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase 3HCDH PF00725.22 OAP53904.1 - 0.062 13.9 0.0 0.09 13.4 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain CorC_HlyC PF03471.17 OAP53905.1 - 0.14 12.2 0.1 13 5.9 0.0 2.5 2 0 0 2 2 2 0 Transporter associated domain Ldh_1_C PF02866.18 OAP53906.1 - 0.0056 16.6 0.0 0.0075 16.2 0.0 1.1 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Peptidase_M19 PF01244.21 OAP53908.1 - 5.1e-05 22.6 0.0 5.5e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Spc7 PF08317.11 OAP53909.1 - 9.4e-06 24.7 1.1 1.3e-05 24.3 1.1 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein zf-RING_UBOX PF13445.6 OAP53909.1 - 1.7e-05 24.7 6.1 5.2e-05 23.2 6.2 1.9 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OAP53909.1 - 0.00017 21.4 11.2 0.00038 20.3 11.2 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OAP53909.1 - 0.00059 19.6 14.9 0.013 15.3 15.1 2.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAP53909.1 - 0.0012 19.1 11.8 0.0027 18.0 11.8 1.6 1 1 0 1 1 1 1 Ring finger domain KASH_CCD PF14662.6 OAP53909.1 - 0.0021 17.9 0.2 0.0028 17.5 0.2 1.1 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH Flagellar_rod PF05149.12 OAP53909.1 - 0.0085 15.6 3.2 0.013 15.0 3.2 1.2 1 0 0 1 1 1 1 Paraflagellar rod protein Golgin_A5 PF09787.9 OAP53909.1 - 0.011 15.2 1.4 0.014 14.8 1.4 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 zf-C3HC4_3 PF13920.6 OAP53909.1 - 0.017 14.9 12.9 0.077 12.9 12.9 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PspA_IM30 PF04012.12 OAP53909.1 - 0.028 14.0 2.8 0.037 13.6 2.8 1.3 1 0 0 1 1 1 0 PspA/IM30 family KxDL PF10241.9 OAP53909.1 - 0.029 14.6 2.0 0.057 13.7 2.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein CENP-F_leu_zip PF10473.9 OAP53909.1 - 0.039 14.0 1.0 0.039 14.0 1.0 1.9 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF724 PF05266.14 OAP53909.1 - 0.056 13.3 0.6 0.089 12.6 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) zf-RING_5 PF14634.6 OAP53909.1 - 0.059 13.3 14.0 1 9.4 15.0 2.2 1 1 1 2 2 2 0 zinc-RING finger domain FUSC PF04632.12 OAP53909.1 - 0.089 11.3 0.9 0.11 11.0 0.9 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family zf-C3HC4_4 PF15227.6 OAP53909.1 - 0.12 12.6 9.6 1 9.6 10.1 2.2 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING OmpH PF03938.14 OAP53909.1 - 0.17 12.2 2.2 0.26 11.6 2.2 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DASH_Spc19 PF08287.11 OAP53909.1 - 1.6 8.6 7.6 0.12 12.3 2.2 1.8 2 0 0 2 2 2 0 Spc19 UDPGP PF01704.18 OAP53910.1 - 1.8e-88 296.9 0.2 3.1e-49 167.7 0.0 2.0 1 1 1 2 2 2 2 UTP--glucose-1-phosphate uridylyltransferase Zn_clus PF00172.18 OAP53914.1 - 5.1e-07 29.7 13.5 9.3e-07 28.9 13.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CCAP PF11105.8 OAP53914.1 - 0.059 13.3 0.2 0.1 12.6 0.2 1.3 1 0 0 1 1 1 0 Arthropod cardioacceleratory peptide 2a PhaP_Bmeg PF09602.10 OAP53915.1 - 0.0053 16.7 1.1 0.01 15.8 1.1 1.5 1 0 0 1 1 1 1 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Tup_N PF08581.10 OAP53915.1 - 0.16 12.3 4.3 1.8 8.9 0.3 3.4 2 1 2 4 4 4 0 Tup N-terminal Pap_E4 PF02711.14 OAP53915.1 - 4.1 8.4 5.6 1.8 9.6 2.3 2.1 2 0 0 2 2 2 0 E4 protein Baculo_LEF5_C PF11792.8 OAP53916.1 - 0.075 12.7 0.8 0.41 10.3 0.1 2.1 2 0 0 2 2 2 0 Baculoviridae late expression factor 5 C-terminal domain DDE_3 PF13358.6 OAP53920.1 - 1.3e-05 24.9 0.0 1.7e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Thioredoxin PF00085.20 OAP53923.1 - 1.9e-05 24.6 0.0 2.5e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Peptidase_C7 PF01830.18 OAP53923.1 - 0.091 12.2 0.1 0.11 11.9 0.1 1.2 1 0 0 1 1 1 0 Peptidase C7 family Oxygenase-NA PF09859.9 OAP53923.1 - 0.12 11.9 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Oxygenase, catalysing oxidative methylation of damaged DNA ASF1_hist_chap PF04729.13 OAP53926.1 - 8.8e-23 81.0 0.0 1.3e-22 80.4 0.0 1.2 1 0 0 1 1 1 1 ASF1 like histone chaperone RNA_pol_I_A49 PF06870.12 OAP53926.1 - 2.5e-06 26.6 0.0 3.6e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor zf-RING_4 PF14570.6 OAP53930.1 - 1.2 8.9 7.2 1.2 9.0 5.5 1.9 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain DUF3910 PF13049.6 OAP53933.1 - 0.017 15.4 0.0 0.02 15.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3910) Myofilin PF15929.5 OAP53940.1 - 0.15 12.5 0.0 0.28 11.5 0.0 1.6 1 0 0 1 1 1 0 Myofilin RNA_pol_Rpb2_6 PF00562.28 OAP53943.1 - 0.00011 21.4 0.1 0.53 9.3 0.0 2.9 3 0 0 3 3 3 2 RNA polymerase Rpb2, domain 6 RT_RNaseH PF17917.1 OAP53947.1 - 2.9e-07 30.7 0.0 0.013 15.8 0.0 2.1 1 1 1 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 OAP53947.1 - 3.4e-06 27.0 0.0 0.0009 19.2 0.0 2.2 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase MAD PF05557.13 OAP53948.1 - 0.018 13.5 0.5 0.023 13.1 0.5 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein DUF3584 PF12128.8 OAP53948.1 - 0.046 11.2 1.0 0.057 10.9 1.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) WD40_alt PF14077.6 OAP53948.1 - 0.063 13.2 0.1 0.14 12.1 0.1 1.5 1 0 0 1 1 1 0 Alternative WD40 repeat motif Shugoshin_N PF07558.11 OAP53948.1 - 0.15 11.9 0.4 0.28 11.1 0.4 1.4 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region YabA PF06156.13 OAP53949.1 - 0.06 14.0 0.5 0.06 14.0 0.5 1.7 2 0 0 2 2 2 0 Initiation control protein YabA DUF982 PF06169.12 OAP53949.1 - 0.22 11.6 1.2 11 6.1 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF982) HTH_53 PF18606.1 OAP53949.1 - 0.66 9.7 2.5 1.1 9.0 0.1 2.2 2 0 0 2 2 2 0 Zap helix turn helix N-terminal domain Muted PF14942.6 OAP53949.1 - 2.4 8.5 6.1 2.8 8.3 0.8 2.2 2 1 0 2 2 2 0 Organelle biogenesis, Muted-like protein KELK PF15796.5 OAP53949.1 - 2.7 8.5 6.8 1.9 9.0 1.3 2.9 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase MIP-T3_C PF17749.1 OAP53951.1 - 0.036 14.0 1.6 0.04 13.9 0.0 1.8 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region ImpE PF07024.13 OAP53952.1 - 0.018 15.1 0.1 0.027 14.5 0.1 1.3 1 0 0 1 1 1 0 ImpE protein Chromo PF00385.24 OAP53953.1 - 2.8e-08 33.5 0.4 7.5e-08 32.2 0.4 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain GBR_NSP5 PF17580.2 OAP53953.1 - 0.13 12.1 2.3 0.24 11.2 2.3 1.4 1 0 0 1 1 1 0 Group B Rotavirus Non-structural protein 5 DDRGK PF09756.9 OAP53953.1 - 0.38 10.3 11.9 0.61 9.6 11.9 1.3 1 0 0 1 1 1 0 DDRGK domain NARP1 PF12569.8 OAP53953.1 - 1.1 8.0 10.7 0.95 8.3 9.1 1.6 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 DUF4594 PF15266.6 OAP53957.1 - 0.2 12.0 4.0 4.8 7.5 0.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4594) CDT1_C PF16679.5 OAP53958.1 - 0.073 13.5 0.3 0.12 12.9 0.3 1.3 1 0 0 1 1 1 0 DNA replication factor Cdt1 C-terminal domain RAB3GAP2_N PF14655.6 OAP53958.1 - 0.11 11.8 0.5 0.13 11.5 0.5 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF4106 PF13388.6 OAP53958.1 - 7.6 5.7 10.5 9.1 5.4 10.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) HMG_box PF00505.19 OAP53959.1 - 2.1e-20 72.9 0.2 3.8e-20 72.1 0.2 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 OAP53959.1 - 1.7e-06 28.5 0.1 3.8e-06 27.4 0.1 1.5 1 0 0 1 1 1 1 HMG-box domain CHDNT PF08073.12 OAP53959.1 - 0.11 12.4 0.1 0.31 11.0 0.1 1.7 1 0 0 1 1 1 0 CHDNT (NUC034) domain YABBY PF04690.13 OAP53959.1 - 2.8 8.5 4.7 1.6 9.3 0.4 2.2 1 1 1 2 2 2 0 YABBY protein DUF2070 PF09843.9 OAP53961.1 - 0.19 9.9 13.7 0.25 9.6 13.7 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) TetR_C_8 PF14278.6 OAP53965.1 - 0.0068 16.5 0.1 3.2 7.9 0.0 2.4 2 0 0 2 2 2 2 Transcriptional regulator C-terminal region Abhydrolase_3 PF07859.13 OAP53968.1 - 5.1e-06 26.5 0.0 1e-05 25.5 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold LRR_adjacent PF08191.11 OAP53968.1 - 0.083 13.1 0.0 0.22 11.7 0.0 1.7 1 0 0 1 1 1 0 LRR adjacent Transp_cyt_pur PF02133.15 OAP53969.1 - 5.6e-11 41.9 0.2 5.6e-11 41.9 0.2 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin MIP PF00230.20 OAP53969.1 - 0.061 13.0 0.1 0.069 12.8 0.1 1.1 1 0 0 1 1 1 0 Major intrinsic protein Herpes_glycop PF01528.16 OAP53969.1 - 0.1 11.4 0.1 0.12 11.3 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus glycoprotein M TFIIA PF03153.13 OAP53970.1 - 1.3 9.0 6.8 1.6 8.7 6.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ABC_tran PF00005.27 OAP53972.1 - 5.1e-07 30.3 0.0 6.2e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 ABC transporter SbcCD_C PF13558.6 OAP53972.1 - 0.075 13.3 0.0 0.23 11.7 0.0 1.8 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Baculo_PEP_C PF04513.12 OAP53973.1 - 5.4e-06 26.5 2.0 1.3e-05 25.2 2.0 1.7 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_13 PF13166.6 OAP53973.1 - 1.6e-05 23.8 0.6 2e-05 23.5 0.6 1.0 1 0 0 1 1 1 1 AAA domain Spc7 PF08317.11 OAP53973.1 - 0.00016 20.7 0.0 0.00021 20.3 0.0 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF1664 PF07889.12 OAP53973.1 - 0.0046 17.0 3.7 0.0046 17.0 3.7 2.0 2 1 0 2 2 1 1 Protein of unknown function (DUF1664) LPP PF04728.13 OAP53973.1 - 0.0049 17.2 2.4 0.4 11.1 0.3 2.6 1 1 1 2 2 2 1 Lipoprotein leucine-zipper Phage_Mu_Gam PF07352.12 OAP53973.1 - 0.0064 16.4 1.6 0.13 12.1 0.0 2.1 1 1 1 2 2 2 1 Bacteriophage Mu Gam like protein DUF2096 PF09869.9 OAP53973.1 - 0.0084 16.2 0.4 0.012 15.7 0.4 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2096) Tektin PF03148.14 OAP53973.1 - 0.0088 14.8 1.8 0.013 14.3 1.8 1.1 1 0 0 1 1 1 1 Tektin family APG17 PF04108.12 OAP53973.1 - 0.026 13.6 0.8 0.036 13.2 0.8 1.1 1 0 0 1 1 1 0 Autophagy protein Apg17 AIP3 PF03915.13 OAP53973.1 - 0.034 13.2 0.5 0.044 12.9 0.5 1.1 1 0 0 1 1 1 0 Actin interacting protein 3 DUF5344 PF17279.2 OAP53973.1 - 0.039 14.5 3.9 0.1 13.2 1.0 2.3 1 1 1 2 2 2 0 Family of unknown function (DUF5344) DUF2730 PF10805.8 OAP53973.1 - 0.041 14.0 0.4 6.2 7.0 1.1 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) Allexi_40kDa PF05549.11 OAP53973.1 - 0.068 12.7 0.1 0.099 12.1 0.1 1.3 1 0 0 1 1 1 0 Allexivirus 40kDa protein WEMBL PF05701.11 OAP53973.1 - 0.074 11.7 0.1 0.098 11.3 0.1 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light CENP-F_leu_zip PF10473.9 OAP53973.1 - 0.078 13.0 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IFT57 PF10498.9 OAP53973.1 - 0.094 11.7 0.6 0.16 10.9 0.6 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 SKA2 PF16740.5 OAP53973.1 - 0.095 12.5 1.1 13 5.6 0.0 2.4 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 DUF848 PF05852.11 OAP53973.1 - 0.1 12.7 0.9 10 6.2 0.0 2.2 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Zw10 PF06248.13 OAP53973.1 - 0.11 11.1 1.6 0.21 10.1 1.6 1.4 1 1 0 1 1 1 0 Centromere/kinetochore Zw10 Filament PF00038.21 OAP53973.1 - 0.14 11.8 0.1 0.19 11.3 0.1 1.1 1 0 0 1 1 1 0 Intermediate filament protein TMPIT PF07851.13 OAP53973.1 - 0.14 11.4 0.1 0.2 10.9 0.1 1.2 1 0 0 1 1 1 0 TMPIT-like protein Apolipoprotein PF01442.18 OAP53973.1 - 0.15 12.0 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain PhaP_Bmeg PF09602.10 OAP53973.1 - 0.15 12.0 0.1 0.23 11.4 0.1 1.2 1 0 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Plasmid_RAQPRD PF09686.10 OAP53973.1 - 0.15 12.3 0.3 2.2 8.6 0.3 2.6 1 1 0 1 1 1 0 Plasmid protein of unknown function (Plasmid_RAQPRD) Bacillus_HBL PF05791.11 OAP53973.1 - 0.18 11.7 4.3 0.41 10.5 2.7 2.3 2 1 0 2 2 1 0 Bacillus haemolytic enterotoxin (HBL) DivIC PF04977.15 OAP53973.1 - 0.19 11.5 1.0 4.6 7.1 0.1 2.5 1 1 1 2 2 2 0 Septum formation initiator Prominin PF05478.11 OAP53973.1 - 0.25 9.2 5.0 0.021 12.8 0.4 1.5 2 0 0 2 2 2 0 Prominin Fib_alpha PF08702.10 OAP53973.1 - 0.27 11.4 3.2 0.56 10.4 2.6 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF1515 PF07439.11 OAP53973.1 - 0.3 11.1 2.9 0.63 10.1 2.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1515) FlaC_arch PF05377.11 OAP53973.1 - 0.32 11.4 4.8 2.9 8.3 0.2 3.0 2 1 1 3 3 2 0 Flagella accessory protein C (FlaC) Phage_HK97_TLTM PF06120.11 OAP53973.1 - 0.39 9.9 4.3 0.57 9.3 4.3 1.2 1 0 0 1 1 1 0 Tail length tape measure protein DUF1192 PF06698.11 OAP53973.1 - 0.42 10.7 3.6 38 4.4 0.0 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF1192) Syntaxin_2 PF14523.6 OAP53973.1 - 0.68 10.3 4.8 18 5.7 0.1 2.4 1 1 1 2 2 2 0 Syntaxin-like protein TssO PF17561.2 OAP53973.1 - 0.76 9.9 4.1 3.5 7.7 2.7 2.2 2 1 0 2 2 2 0 Type VI secretion system, TssO Laminin_II PF06009.12 OAP53973.1 - 0.79 9.7 6.3 0.1 12.6 2.1 1.8 2 0 0 2 2 1 0 Laminin Domain II NPV_P10 PF05531.12 OAP53973.1 - 1.2 9.6 9.6 17 6.0 8.9 2.6 2 1 0 2 2 1 0 Nucleopolyhedrovirus P10 protein CLP_protease PF00574.23 OAP53978.1 - 1.6e-42 145.4 0.0 2e-42 145.1 0.0 1.0 1 0 0 1 1 1 1 Clp protease PBP_like PF12727.7 OAP53979.1 - 0.027 13.6 0.1 0.039 13.1 0.1 1.3 1 0 0 1 1 1 0 PBP superfamily domain Peptidase_C48 PF02902.19 OAP53980.1 - 2.4e-05 24.3 0.1 6.1e-05 23.0 0.1 1.6 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Agenet PF05641.12 OAP53980.1 - 0.051 14.0 0.0 0.13 12.8 0.0 1.7 1 0 0 1 1 1 0 Agenet domain CDC45 PF02724.14 OAP53980.1 - 1 7.5 9.5 1.6 7.0 9.5 1.2 1 0 0 1 1 1 0 CDC45-like protein CHAT PF12770.7 OAP53981.1 - 2.7e-27 95.9 0.7 6.9e-27 94.6 0.7 1.6 1 0 0 1 1 1 1 CHAT domain TPR_10 PF13374.6 OAP53981.1 - 0.00065 19.5 6.1 0.94 9.4 0.0 4.6 2 2 1 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 OAP53981.1 - 0.0016 18.7 1.4 4.8 7.5 0.0 4.9 5 1 1 6 6 6 2 Tetratricopeptide repeat Peptidase_C25 PF01364.18 OAP53981.1 - 0.0049 16.1 0.0 0.0075 15.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C25 TPR_14 PF13428.6 OAP53981.1 - 0.045 14.6 5.5 9.7 7.3 0.1 5.3 4 1 1 5 5 5 0 Tetratricopeptide repeat DEAD PF00270.29 OAP53982.1 - 8.3e-12 45.2 0.0 9.3e-12 45.1 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase p450 PF00067.22 OAP53984.1 - 8.9e-12 44.5 0.0 1e-11 44.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 QSregVF_b PF12843.7 OAP53984.1 - 0.019 14.8 0.1 0.04 13.8 0.1 1.5 1 0 0 1 1 1 0 Putative quorum-sensing-regulated virulence factor ATP_bind_2 PF03668.15 OAP53984.1 - 0.034 13.5 0.0 0.05 12.9 0.0 1.2 1 0 0 1 1 1 0 P-loop ATPase protein family Aminotran_1_2 PF00155.21 OAP53989.1 - 4.5e-07 29.4 0.0 1.4e-06 27.8 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class I and II DUF3716 PF12511.8 OAP53992.1 - 1.2e-15 57.2 2.0 1.9e-15 56.6 2.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) Head-tail_con PF12236.8 OAP53993.1 - 0.17 10.3 0.0 0.22 9.9 0.0 1.1 1 0 0 1 1 1 0 Bacteriophage head to tail connecting protein Methyltransf_23 PF13489.6 OAP53997.1 - 1.1e-16 61.1 0.0 1.6e-16 60.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAP53997.1 - 1.1e-07 32.4 0.0 2.9e-07 31.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAP53997.1 - 1.1e-06 28.5 0.0 0.044 13.6 0.0 2.5 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_11 PF08241.12 OAP53997.1 - 0.00015 22.3 0.0 0.00033 21.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 OAP53997.1 - 0.0015 18.0 0.0 0.0025 17.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.12 OAP53997.1 - 0.003 18.2 0.0 0.038 14.7 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OAP53997.1 - 0.0086 15.6 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain F-box-like PF12937.7 OAP53999.1 - 0.00036 20.4 0.5 0.00036 20.4 0.5 2.2 2 0 0 2 2 2 1 F-box-like DUF3669 PF12417.8 OAP54000.1 - 3.7e-17 62.3 0.1 1e-16 60.9 0.1 1.7 1 0 0 1 1 1 1 Zinc finger protein F-box PF00646.33 OAP54002.1 - 0.00064 19.5 0.0 0.0016 18.3 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 OAP54002.1 - 0.0032 17.3 0.0 0.0075 16.1 0.0 1.6 1 0 0 1 1 1 1 F-box-like CbiQ PF02361.16 OAP54005.1 - 0.026 14.2 1.1 0.027 14.1 1.1 1.0 1 0 0 1 1 1 0 Cobalt transport protein DUF4534 PF15049.6 OAP54005.1 - 0.078 12.7 2.2 0.094 12.5 2.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4534) DUF4307 PF14155.6 OAP54005.1 - 0.095 12.5 0.8 0.13 12.1 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4307) Cep3 PF16846.5 OAP54005.1 - 0.17 10.3 0.0 0.17 10.3 0.0 1.0 1 0 0 1 1 1 0 Centromere DNA-binding protein complex CBF3 subunit B Kelch_4 PF13418.6 OAP54006.1 - 0.075 13.0 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Galactose oxidase, central domain DUF919 PF06034.11 OAP54006.1 - 0.18 11.7 0.1 0.3 10.9 0.1 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF919) Gp58 PF07902.11 OAP54008.1 - 0.0082 14.5 3.3 0.011 14.0 3.3 1.1 1 0 0 1 1 1 1 gp58-like protein FliT PF05400.13 OAP54008.1 - 0.01 16.6 0.8 0.01 16.6 0.8 3.4 2 1 1 3 3 3 0 Flagellar protein FliT Zn_clus PF00172.18 OAP54008.1 - 0.48 10.6 2.0 0.51 10.5 0.4 1.8 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4795 PF16043.5 OAP54008.1 - 0.5 9.9 16.1 0.32 10.6 7.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) EMP24_GP25L PF01105.24 OAP54008.1 - 1.2 9.0 5.4 4.2 7.3 5.3 1.9 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD OmpH PF03938.14 OAP54008.1 - 1.3 9.3 16.5 0.21 11.9 6.5 2.9 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) ACCA PF03255.14 OAP54008.1 - 5.5 6.9 10.4 2.5 8.0 2.5 2.7 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit LPP PF04728.13 OAP54008.1 - 7 7.1 8.3 6.4 7.2 0.2 3.1 3 0 0 3 3 3 0 Lipoprotein leucine-zipper F-box-like PF12937.7 OAP54009.1 - 0.0019 18.1 0.0 0.006 16.5 0.0 1.9 1 0 0 1 1 1 1 F-box-like HSM3_C PF18794.1 OAP54009.1 - 0.018 14.6 0.0 0.035 13.7 0.0 1.5 1 0 0 1 1 1 0 DNA mismatch repair protein HSM3, C terminal domain Pkinase PF00069.25 OAP54011.1 - 1.7e-22 80.1 0.0 2.1e-22 79.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP54011.1 - 1.4e-08 34.4 0.1 1.6e-08 34.2 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OAP54011.1 - 0.0045 16.9 0.5 0.017 15.0 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 OAP54011.1 - 0.15 11.6 0.0 0.26 10.8 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase F-box-like PF12937.7 OAP54013.1 - 0.0048 16.8 0.0 0.026 14.4 0.0 2.1 2 0 0 2 2 2 1 F-box-like Cytochrom_c3_2 PF14537.6 OAP54013.1 - 0.077 13.5 0.1 0.077 13.5 0.1 2.5 4 0 0 4 4 4 0 Cytochrome c3 Cytochrome_C7 PF14522.6 OAP54013.1 - 1.3 9.1 8.5 0.13 12.3 0.6 2.9 1 1 1 2 2 2 0 Cytochrome c7 and related cytochrome c zf-RING_2 PF13639.6 OAP54014.1 - 9.9e-05 22.6 13.3 0.00016 21.9 13.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 OAP54014.1 - 0.00017 21.4 12.7 0.0003 20.6 12.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PDDEXK_6 PF04720.12 OAP54014.1 - 0.0032 17.4 0.4 0.0046 16.9 0.4 1.3 1 0 0 1 1 1 1 PDDEXK-like family of unknown function zf-C3HC4_2 PF13923.6 OAP54014.1 - 0.012 15.4 13.3 0.029 14.2 13.3 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OAP54014.1 - 0.016 15.1 10.3 0.028 14.3 10.3 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 OAP54014.1 - 0.029 14.7 6.9 0.069 13.4 6.9 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain DUF677 PF05055.12 OAP54014.1 - 0.038 12.9 1.3 0.051 12.5 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF677) zf-C3HC4_4 PF15227.6 OAP54014.1 - 0.05 13.8 12.4 0.45 10.7 12.5 2.4 1 1 2 3 3 3 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 OAP54014.1 - 0.1 12.5 12.7 0.52 10.3 13.1 2.0 1 1 1 2 2 2 0 zinc-RING finger domain CENP-F_leu_zip PF10473.9 OAP54014.1 - 0.12 12.4 5.5 0.19 11.8 5.5 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SlyX PF04102.12 OAP54014.1 - 0.2 12.3 4.2 0.58 10.8 0.4 2.4 1 1 1 2 2 2 0 SlyX PRKG1_interact PF15898.5 OAP54014.1 - 0.25 12.2 4.4 0.9 10.5 0.2 2.3 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain zf-RING_10 PF16685.5 OAP54014.1 - 0.3 11.3 6.4 0.65 10.2 6.4 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 Rx_N PF18052.1 OAP54014.1 - 0.32 11.3 7.6 0.4 11.0 0.6 2.2 1 1 1 2 2 2 0 Rx N-terminal domain zf-RING_UBOX PF13445.6 OAP54014.1 - 0.38 10.8 8.4 0.37 10.8 6.9 1.7 1 1 0 1 1 1 0 RING-type zinc-finger HIP1_clath_bdg PF16515.5 OAP54014.1 - 0.41 11.3 5.3 0.85 10.3 4.4 1.8 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 zf-RING_13 PF17977.1 OAP54014.1 - 1 9.5 7.0 1.6 8.9 7.0 1.2 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF1192 PF06698.11 OAP54014.1 - 2 8.5 5.8 0.63 10.1 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) TMF_DNA_bd PF12329.8 OAP54014.1 - 5.7 7.0 7.1 0.76 9.8 1.3 2.1 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Peptidase_M29 PF02073.15 OAP54019.1 - 0.11 11.2 0.2 0.16 10.7 0.2 1.3 1 0 0 1 1 1 0 Thermophilic metalloprotease (M29) Pkinase PF00069.25 OAP54020.1 - 8.7e-45 153.1 0.0 1.4e-44 152.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP54020.1 - 2.2e-23 82.9 0.0 3.6e-23 82.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 OAP54020.1 - 0.0025 18.1 0.1 0.0057 17.0 0.1 1.6 1 0 0 1 1 1 1 FHA domain Kdo PF06293.14 OAP54020.1 - 0.0074 15.7 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OAP54020.1 - 0.072 13.0 0.0 0.17 11.8 0.0 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family NDT80_PhoG PF05224.12 OAP54022.1 - 5.2e-11 43.1 0.0 8.9e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family ABC_tran PF00005.27 OAP54023.1 - 2.8e-08 34.4 0.0 4.3e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 ABC transporter MCR_beta_N PF02783.15 OAP54023.1 - 0.06 13.0 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Methyl-coenzyme M reductase beta subunit, N-terminal domain SbcCD_C PF13558.6 OAP54023.1 - 0.12 12.6 1.0 3 8.2 1.2 2.6 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit DUF1479 PF07350.12 OAP54024.1 - 2.5e-05 23.3 0.0 3.1e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) Peptidase_S64 PF08192.11 OAP54025.1 - 2.2e-06 26.5 0.0 3e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase family S64 Peptidase_S3 PF00944.19 OAP54025.1 - 0.00036 20.4 0.1 0.0006 19.7 0.1 1.3 1 0 0 1 1 1 1 Alphavirus core protein Trypsin_2 PF13365.6 OAP54025.1 - 0.0014 19.5 0.1 0.0033 18.3 0.1 1.7 1 1 0 1 1 1 1 Trypsin-like peptidase domain Peptidase_S32 PF05579.13 OAP54025.1 - 0.032 13.4 0.4 0.051 12.8 0.4 1.2 1 0 0 1 1 1 0 Equine arteritis virus serine endopeptidase S32 Peptidase_S46 PF10459.9 OAP54025.1 - 0.072 11.7 0.1 0.12 11.0 0.1 1.2 1 0 0 1 1 1 0 Peptidase S46 Trypsin PF00089.26 OAP54025.1 - 0.1 12.4 0.1 0.19 11.5 0.1 1.4 1 0 0 1 1 1 0 Trypsin MLVIN_C PF18697.1 OAP54026.1 - 0.14 12.3 0.0 4.9 7.3 0.0 2.5 2 0 0 2 2 2 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain DUF3819 PF12842.7 OAP54026.1 - 0.14 12.0 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3819) Elf1 PF05129.13 OAP54027.1 - 2.2e-21 75.7 0.2 2.2e-21 75.7 0.2 2.7 3 0 0 3 3 3 1 Transcription elongation factor Elf1 like PT-HINT PF07591.11 OAP54027.1 - 0.086 13.1 5.1 4.3 7.6 0.4 2.8 2 1 1 3 3 3 0 Pretoxin HINT domain Phage_gp53 PF11246.8 OAP54027.1 - 0.099 12.3 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Base plate wedge protein 53 DUF1143 PF06608.11 OAP54027.1 - 0.18 11.9 1.6 1.6 8.8 0.0 2.7 3 1 1 4 4 4 0 Protein of unknown function (DUF1143) CsgA PF17334.2 OAP54028.1 - 0.18 12.5 0.2 0.38 11.5 0.2 1.4 1 0 0 1 1 1 0 Minor curli fiber component A Zn_clus PF00172.18 OAP54030.1 - 4.6e-06 26.7 11.0 8.6e-06 25.8 11.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HNH_2 PF13391.6 OAP54031.1 - 7e-07 29.3 0.0 1.5e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease DUF3584 PF12128.8 OAP54031.1 - 3.3 5.1 37.4 0.47 7.9 24.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) OTT_1508_deam PF14441.6 OAP54033.1 - 0.0053 16.7 1.1 0.017 15.2 1.1 1.9 1 1 0 1 1 1 1 OTT_1508-like deaminase HNH_2 PF13391.6 OAP54034.1 - 1.3e-05 25.2 0.0 2.8e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease NACHT_N PF17100.5 OAP54034.1 - 0.025 14.4 6.8 0.048 13.5 6.8 1.4 1 0 0 1 1 1 0 N-terminal domain of NWD NACHT-NTPase PKcGMP_CC PF16808.5 OAP54034.1 - 0.048 13.5 13.1 1.5 8.8 0.1 4.2 1 1 2 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase TPR_7 PF13176.6 OAP54034.1 - 0.48 10.6 2.2 11 6.3 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Spc7 PF08317.11 OAP54034.1 - 1.3 7.9 27.2 0.17 10.7 12.8 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein LCD1 PF09798.9 OAP54034.1 - 4.3 5.7 15.0 12 4.3 15.0 1.7 1 1 0 1 1 1 0 DNA damage checkpoint protein DUF4158 PF13700.6 OAP54035.1 - 0.065 13.1 0.0 0.074 12.9 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4158) zf-RanBP PF00641.18 OAP54039.1 - 0.0063 15.8 3.3 0.011 15.0 3.3 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others DUF848 PF05852.11 OAP54039.1 - 0.13 12.3 2.5 0.63 10.1 1.0 2.2 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) PP-binding PF00550.25 OAP54042.1 - 4.4e-11 43.0 0.1 7.5e-11 42.2 0.1 1.4 1 0 0 1 1 1 1 Phosphopantetheine attachment site HEAT_EZ PF13513.6 OAP54042.1 - 7.8e-11 42.2 0.4 0.0005 20.5 0.1 2.6 2 0 0 2 2 2 2 HEAT-like repeat HEAT_2 PF13646.6 OAP54042.1 - 3.4e-06 27.4 0.1 0.019 15.3 0.0 2.8 1 1 2 3 3 3 2 HEAT repeats HEAT PF02985.22 OAP54042.1 - 6.8e-06 25.9 0.6 0.032 14.5 0.0 3.5 3 0 0 3 3 3 2 HEAT repeat Arm PF00514.23 OAP54042.1 - 0.0015 18.5 0.3 1 9.5 0.1 3.5 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat MMS19_C PF12460.8 OAP54042.1 - 0.0021 17.2 0.3 0.0045 16.2 0.2 1.6 1 1 1 2 2 2 1 RNAPII transcription regulator C-terminal CLASP_N PF12348.8 OAP54042.1 - 0.0048 16.5 0.1 0.0098 15.5 0.1 1.5 1 1 0 1 1 1 1 CLASP N terminal Vac14_Fab1_bd PF12755.7 OAP54042.1 - 0.03 14.9 0.0 1.8 9.2 0.0 2.3 1 1 1 2 2 2 0 Vacuolar 14 Fab1-binding region SPC25 PF06703.11 OAP54043.1 - 8.5e-25 87.4 0.1 1e-24 87.2 0.1 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) DUF5039 PF16442.5 OAP54043.1 - 0.052 13.1 0.2 0.064 12.8 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5039) Adaptin_N PF01602.20 OAP54044.1 - 4.7e-07 28.7 0.0 5.2e-07 28.6 0.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region DUF975 PF06161.11 OAP54044.1 - 0.074 12.8 0.1 0.086 12.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF975) ABC_membrane PF00664.23 OAP54046.1 - 0.00017 21.3 0.9 0.00021 21.0 0.9 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region Selenoprotein_S PF06936.11 OAP54046.1 - 0.06 13.2 0.1 0.095 12.5 0.1 1.3 1 0 0 1 1 1 0 Selenoprotein S (SelS) DUF1816 PF08846.10 OAP54046.1 - 0.083 12.9 0.1 0.33 11.0 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1816) DUF4381 PF14316.6 OAP54046.1 - 0.084 13.1 0.6 0.12 12.7 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Bac_export_2 PF01312.19 OAP54046.1 - 0.13 11.5 0.7 0.17 11.0 0.7 1.2 1 0 0 1 1 1 0 FlhB HrpN YscU SpaS Family SET PF00856.28 OAP54048.1 - 1e-15 58.5 2.4 2.9e-14 53.8 0.1 2.2 1 1 1 2 2 2 2 SET domain Peptidase_S64 PF08192.11 OAP54049.1 - 0.00019 20.1 0.4 0.18 10.2 0.0 2.3 2 0 0 2 2 2 2 Peptidase family S64 Histone PF00125.24 OAP54050.1 - 2.6e-38 131.3 0.1 3.1e-38 131.1 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 OAP54050.1 - 2e-06 28.1 0.0 3e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 OAP54050.1 - 2.3e-06 27.7 0.0 4.5e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIID-31kDa PF02291.15 OAP54050.1 - 0.00056 20.0 0.0 0.00086 19.4 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit CBFD_NFYB_HMF PF00808.23 OAP54050.1 - 0.0038 17.5 0.0 0.0083 16.4 0.0 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF4407 PF14362.6 OAP54051.1 - 0.063 12.6 4.0 0.094 12.1 4.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) V-set PF07686.17 OAP54052.1 - 0.13 12.4 0.0 1.6 9.0 0.0 2.3 2 0 0 2 2 2 0 Immunoglobulin V-set domain Abhydrolase_3 PF07859.13 OAP54053.1 - 1.3e-07 31.7 0.0 2.2e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold LRR_adjacent PF08191.11 OAP54053.1 - 0.085 13.1 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 LRR adjacent ImpE PF07024.13 OAP54053.1 - 0.16 12.1 0.7 2 8.5 0.0 2.2 2 0 0 2 2 2 0 ImpE protein BBE PF08031.12 OAP54055.1 - 0.0024 17.9 0.8 0.005 16.9 0.8 1.5 1 0 0 1 1 1 1 Berberine and berberine like DUF325 PF03804.13 OAP54056.1 - 0.025 14.6 0.0 0.039 14.0 0.0 1.3 1 0 0 1 1 1 0 Viral proteins of unknown function PTPRCAP PF15713.5 OAP54057.1 - 0.0037 17.6 2.9 0.0044 17.3 2.9 1.2 1 0 0 1 1 1 1 Protein tyrosine phosphatase receptor type C-associated Na_trans_assoc PF06512.13 OAP54057.1 - 0.015 15.6 3.1 0.019 15.2 3.1 1.3 1 0 0 1 1 1 0 Sodium ion transport-associated CobT PF06213.12 OAP54057.1 - 0.041 13.3 7.3 0.051 13.0 7.3 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT TRAP_alpha PF03896.16 OAP54057.1 - 0.14 11.3 2.9 0.16 11.1 2.9 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Pes-10 PF07149.11 OAP54057.1 - 0.31 10.1 8.6 0.36 9.8 8.6 1.1 1 0 0 1 1 1 0 Pes-10 CDC45 PF02724.14 OAP54057.1 - 0.42 8.8 6.8 0.46 8.7 6.8 1.0 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 OAP54057.1 - 0.42 8.8 10.6 0.46 8.6 10.6 1.0 1 0 0 1 1 1 0 Nop14-like family COPI_C PF06957.11 OAP54057.1 - 0.66 8.7 3.8 0.78 8.4 3.8 1.0 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus Roughex PF06020.11 OAP54057.1 - 0.67 9.0 6.6 0.76 8.8 6.6 1.1 1 0 0 1 1 1 0 Drosophila roughex protein SDA1 PF05285.12 OAP54057.1 - 0.89 8.9 11.0 1 8.7 11.0 1.0 1 0 0 1 1 1 0 SDA1 RT_RNaseH_2 PF17919.1 OAP54059.1 - 7.5e-17 61.2 0.1 2.3e-16 59.6 0.1 1.7 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAP54059.1 - 5.3e-07 29.9 0.0 1.6e-06 28.3 0.0 1.7 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase PPV_E1_N PF00524.18 OAP54059.1 - 0.012 16.1 0.0 0.018 15.4 0.0 1.3 1 0 0 1 1 1 0 E1 Protein, N terminal domain p450 PF00067.22 OAP54060.1 - 0.038 12.7 0.0 0.051 12.3 0.0 1.1 1 0 0 1 1 1 0 Cytochrome P450 Exonuc_VII_L PF02601.15 OAP54062.1 - 0.078 12.5 18.7 0.13 11.9 18.7 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit Atg29_N PF18388.1 OAP54062.1 - 0.14 12.0 1.8 17 5.3 0.0 2.5 2 0 0 2 2 2 0 Atg29 N-terminal domain Activator_LAG-3 PF11498.8 OAP54062.1 - 0.43 9.5 72.5 0.84 8.5 72.5 1.6 1 0 0 1 1 1 0 Transcriptional activator LAG-3 LMBR1 PF04791.16 OAP54062.1 - 4.3 6.1 6.3 6 5.7 6.3 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Transcrip_reg PF01709.20 OAP54063.1 - 7.6e-08 32.1 1.4 1.1e-07 31.6 1.4 1.1 1 0 0 1 1 1 1 Transcriptional regulator DUF3842 PF12953.7 OAP54063.1 - 0.061 13.7 0.1 0.088 13.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3842) Peptidase_M66 PF10462.9 OAP54064.1 - 0.03 13.3 0.0 0.034 13.1 0.0 1.1 1 0 0 1 1 1 0 Peptidase M66 Imm2 PF14426.6 OAP54075.1 - 6.1e-06 26.2 0.1 2.4 8.3 0.0 5.1 4 2 0 4 4 4 2 Immunity protein Imm2 CdiI_2 PF18593.1 OAP54075.1 - 0.0025 18.4 0.1 9.2 7.0 0.0 4.6 1 1 5 6 6 6 1 CdiI immunity protein Helicase_C_3 PF13625.6 OAP54075.1 - 0.0051 17.0 0.7 19 5.4 0.0 4.4 1 1 4 5 5 5 1 Helicase conserved C-terminal domain PET117 PF15786.5 OAP54075.1 - 0.052 13.8 0.9 6.5 7.1 0.9 3.7 1 1 0 1 1 1 0 PET assembly of cytochrome c oxidase, mitochondrial CK2S PF15011.6 OAP54075.1 - 0.22 11.4 1.7 3.1 7.7 0.1 3.3 1 1 1 3 3 3 0 Casein Kinase 2 substrate RPAP1_C PF08620.10 OAP54075.1 - 0.32 11.2 7.5 18 5.5 0.2 4.9 2 2 3 6 6 6 0 RPAP1-like, C-terminal AAA_12 PF13087.6 OAP54077.1 - 6.3e-16 58.6 0.0 7e-16 58.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain Homeodomain PF00046.29 OAP54078.1 - 7.2e-10 38.6 0.3 1.4e-09 37.7 0.3 1.4 1 0 0 1 1 1 1 Homeodomain EFG_II PF14492.6 OAP54078.1 - 0.071 13.2 0.2 0.2 11.8 0.1 1.7 2 0 0 2 2 2 0 Elongation Factor G, domain II RAP1 PF07218.11 OAP54079.1 - 0.24 9.7 0.1 0.26 9.5 0.1 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) NPFF PF15085.6 OAP54080.1 - 0.0076 16.6 0.3 1.4 9.3 0.0 2.1 1 1 0 2 2 2 2 Neuropeptide FF Halo_GVPC PF05465.13 OAP54080.1 - 0.027 14.7 0.4 6.6 7.1 0.0 2.4 2 0 0 2 2 2 0 Halobacterial gas vesicle protein C (GVPC) repeat Med26 PF08711.11 OAP54082.1 - 5.9e-06 26.2 0.4 1.4e-05 25.0 0.4 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain FAM176 PF14851.6 OAP54082.1 - 0.17 11.5 0.8 0.35 10.5 0.8 1.5 1 0 0 1 1 1 0 FAM176 family Oxysterol_BP PF01237.18 OAP54084.1 - 1.8e-05 23.7 0.2 3.5e-05 22.8 0.0 1.5 2 0 0 2 2 2 1 Oxysterol-binding protein NESP55 PF06390.12 OAP54084.1 - 0.073 12.7 1.0 0.12 12.0 1.0 1.2 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) Dynamin_N PF00350.23 OAP54089.1 - 0.00036 20.6 0.0 0.00056 20.0 0.0 1.2 1 0 0 1 1 1 1 Dynamin family DUF726 PF05277.12 OAP54091.1 - 0.002 17.1 0.0 0.002 17.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) adh_short PF00106.25 OAP54092.1 - 2.7e-18 66.1 0.0 4.5e-18 65.4 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP54092.1 - 1.6e-13 50.7 0.0 2.4e-13 50.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase CAP_N PF01213.19 OAP54092.1 - 0.0096 15.4 0.4 0.013 15.0 0.4 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal Glyco_transf_5 PF08323.11 OAP54092.1 - 0.18 11.4 0.0 0.27 10.9 0.0 1.2 1 0 0 1 1 1 0 Starch synthase catalytic domain JmjC PF02373.22 OAP54093.1 - 2.8e-16 60.0 0.0 6.9e-16 58.7 0.0 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase SET PF00856.28 OAP54093.1 - 0.0012 19.3 0.6 0.022 15.1 0.0 3.2 3 1 0 3 3 3 1 SET domain Trypan_PARP PF05887.11 OAP54093.1 - 0.0046 16.9 0.2 0.012 15.6 0.2 1.7 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) COA2 PF17051.5 OAP54093.1 - 0.13 12.3 0.4 0.32 11.1 0.4 1.6 1 0 0 1 1 1 0 Cytochrome C oxidase assembly factor 2 APG17 PF04108.12 OAP54096.1 - 0.0011 18.2 0.2 0.0021 17.3 0.2 1.4 1 0 0 1 1 1 1 Autophagy protein Apg17 ImpE PF07024.13 OAP54096.1 - 0.097 12.8 0.0 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 ImpE protein UCH_C PF18031.1 OAP54096.1 - 5.6 7.0 5.6 3.7 7.5 0.7 2.4 2 0 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolases Inositol_P PF00459.25 OAP54097.1 - 3.3e-15 56.3 0.0 5.2e-15 55.7 0.0 1.3 1 1 0 1 1 1 1 Inositol monophosphatase family HET PF06985.11 OAP54100.1 - 0.049 14.0 0.7 16 5.8 0.7 2.7 1 1 1 2 2 2 0 Heterokaryon incompatibility protein (HET) Rot1 PF10681.9 OAP54102.1 - 0.02 14.4 0.0 0.032 13.8 0.0 1.2 1 0 0 1 1 1 0 Chaperone for protein-folding within the ER, fungal eIF-3c_N PF05470.12 OAP54104.1 - 0.99 7.6 7.7 0.18 10.1 0.2 2.0 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DUF2491 PF10679.9 OAP54106.1 - 0.033 13.4 0.0 5 6.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2491) Arginase PF00491.21 OAP54110.1 - 6.3e-10 39.0 0.1 7.8e-10 38.7 0.1 1.1 1 0 0 1 1 1 1 Arginase family UBZ_FAAP20 PF15750.5 OAP54110.1 - 0.14 12.1 1.2 8.7 6.4 0.4 2.7 2 0 0 2 2 2 0 Ubiquitin-binding zinc-finger Rad60-SLD PF11976.8 OAP54111.1 - 7.2e-20 70.6 0.1 9.8e-20 70.2 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 OAP54111.1 - 2.4e-07 30.4 0.0 3.4e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family zf-CCHC_2 PF13696.6 OAP54112.1 - 0.00027 20.7 5.3 0.00042 20.1 5.3 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 OAP54112.1 - 0.0066 16.5 4.5 0.01 15.9 4.5 1.3 1 0 0 1 1 1 1 Zinc knuckle Enolase_N PF03952.16 OAP54115.1 - 2.2e-10 40.8 0.0 4e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain HNH_2 PF13391.6 OAP54115.1 - 3e-08 33.7 0.1 6e-08 32.7 0.1 1.6 1 0 0 1 1 1 1 HNH endonuclease PAH PF02671.21 OAP54117.1 - 6.4e-14 51.8 0.0 1.4e-13 50.8 0.0 1.6 1 1 0 1 1 1 1 Paired amphipathic helix repeat DUF4106 PF13388.6 OAP54117.1 - 0.93 8.7 8.3 1.2 8.3 8.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Trypsin_2 PF13365.6 OAP54118.1 - 0.081 13.8 0.0 0.16 12.8 0.0 1.5 1 1 0 1 1 1 0 Trypsin-like peptidase domain HNH_2 PF13391.6 OAP54119.1 - 2.6e-05 24.2 0.0 5.8e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease EST1_DNA_bind PF10373.9 OAP54120.1 - 2.2e-05 24.1 0.0 0.0011 18.5 0.0 2.4 2 0 0 2 2 2 2 Est1 DNA/RNA binding domain PUB_1 PF18486.1 OAP54120.1 - 0.2 11.5 0.8 0.54 10.1 0.2 2.0 2 0 0 2 2 2 0 PNGase/UBA- or UBX-containing domain Histone PF00125.24 OAP54121.1 - 7e-05 23.2 1.1 0.00021 21.6 0.0 2.0 1 1 1 2 2 2 1 Core histone H2A/H2B/H3/H4 dbPDZ_assoc PF16610.5 OAP54121.1 - 0.023 14.9 2.1 0.036 14.3 2.1 1.3 1 0 0 1 1 1 0 Unstructured region between two PDZ domains on Dlg5 F-box PF00646.33 OAP54124.1 - 0.0014 18.5 1.6 0.0018 18.1 0.0 2.1 2 0 0 2 2 2 1 F-box domain F-box_4 PF15966.5 OAP54124.1 - 0.049 13.5 0.0 0.092 12.6 0.0 1.5 1 0 0 1 1 1 0 F-box F-box-like PF12937.7 OAP54124.1 - 0.059 13.3 0.1 0.14 12.1 0.1 1.6 1 0 0 1 1 1 0 F-box-like zf-C2H2_8 PF15909.5 OAP54124.1 - 0.26 11.6 2.2 0.73 10.2 2.2 1.8 2 0 0 2 2 2 0 C2H2-type zinc ribbon LRR_9 PF14580.6 OAP54124.1 - 0.27 10.7 2.8 0.75 9.3 0.2 2.6 3 0 0 3 3 3 0 Leucine-rich repeat Dodecin PF07311.12 OAP54127.1 - 0.03 14.6 0.8 0.089 13.1 0.3 2.1 2 0 0 2 2 2 0 Dodecin GrpE PF01025.19 OAP54127.1 - 0.19 11.4 2.0 2.9 7.5 0.1 2.7 2 1 0 2 2 2 0 GrpE Baculo_PEP_C PF04513.12 OAP54127.1 - 0.27 11.3 6.9 0.21 11.6 4.1 2.0 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus F-box_4 PF15966.5 OAP54128.1 - 0.00015 21.6 0.1 0.00032 20.5 0.1 1.5 1 0 0 1 1 1 1 F-box F-box PF00646.33 OAP54128.1 - 0.00051 19.8 0.0 0.00093 19.0 0.0 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 OAP54128.1 - 0.0066 16.3 0.0 0.015 15.1 0.0 1.6 1 0 0 1 1 1 1 F-box-like Poxvirus_B22R PF04395.12 OAP54129.1 - 0.038 13.5 1.6 0.042 13.4 1.6 1.0 1 0 0 1 1 1 0 Poxvirus B22R protein Inhibitor_I71 PF12628.7 OAP54129.1 - 0.11 12.4 0.3 0.13 12.0 0.3 1.1 1 0 0 1 1 1 0 Falstatin, cysteine peptidase inhibitor TMEM119 PF15724.5 OAP54129.1 - 0.16 12.0 2.4 0.17 12.0 2.4 1.1 1 0 0 1 1 1 0 TMEM119 family Hep_59 PF07052.11 OAP54130.1 - 0.0054 17.5 0.1 0.012 16.4 0.1 1.5 1 0 0 1 1 1 1 Hepatocellular carcinoma-associated antigen 59 Pacs-1 PF10254.9 OAP54130.1 - 0.19 10.6 1.8 0.25 10.2 1.8 1.1 1 0 0 1 1 1 0 PACS-1 cytosolic sorting protein FAD_binding_4 PF01565.23 OAP54131.1 - 3.1e-25 88.5 0.0 4.1e-25 88.1 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phytase PF02333.15 OAP54132.1 - 0.00052 19.1 0.0 0.00071 18.6 0.0 1.1 1 0 0 1 1 1 1 Phytase zf-C2H2 PF00096.26 OAP54135.1 - 0.0012 19.2 12.1 0.38 11.3 1.4 3.7 3 1 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_aberr PF17017.5 OAP54135.1 - 0.0077 16.4 0.0 0.015 15.5 0.0 1.4 1 0 0 1 1 1 1 Aberrant zinc-finger zf-C2H2_4 PF13894.6 OAP54135.1 - 0.017 15.9 8.4 9.2 7.4 0.5 3.9 3 1 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OAP54135.1 - 0.48 10.9 11.3 5 7.7 0.5 3.6 3 0 0 3 3 3 0 Zinc-finger double domain UQ_con PF00179.26 OAP54136.1 - 2.1e-49 166.8 0.0 2.4e-49 166.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OAP54136.1 - 0.0062 16.2 0.0 0.007 16.1 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 OAP54136.1 - 0.01 16.1 0.0 0.015 15.6 0.0 1.4 1 1 0 1 1 1 0 RWD domain RT_RNaseH_2 PF17919.1 OAP54137.1 - 4.5e-23 81.2 0.0 1.1e-22 79.9 0.0 1.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAP54137.1 - 5.4e-19 68.4 0.0 9.3e-19 67.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 OAP54137.1 - 0.0002 20.9 0.2 0.0012 18.4 0.2 2.0 1 1 1 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) OapA_N PF08525.11 OAP54139.1 - 0.042 13.8 0.4 0.07 13.1 0.4 1.4 1 0 0 1 1 1 0 Opacity-associated protein A N-terminal motif DUF4172 PF13776.6 OAP54139.1 - 0.12 12.7 0.2 1.1 9.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4172) OAM_dimer PF16554.5 OAP54143.1 - 0.065 13.7 0.0 10 6.6 0.0 2.6 2 0 0 2 2 2 0 Dimerisation domain of d-ornithine 4,5-aminomutase HNH_2 PF13391.6 OAP54146.1 - 2.2e-05 24.5 0.2 0.00047 20.2 0.0 2.9 3 0 0 3 3 3 1 HNH endonuclease Abhydrolase_3 PF07859.13 OAP54147.1 - 0.00029 20.8 0.0 0.00034 20.5 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Cation_ATPase_C PF00689.21 OAP54149.1 - 0.0065 16.2 0.1 0.0079 15.9 0.1 1.1 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus WcbI PF18588.1 OAP54150.1 - 0.057 13.0 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis enzyme WcbI FliM PF02154.15 OAP54151.1 - 2.5e-07 30.8 0.6 0.48 10.3 0.0 3.1 1 1 2 3 3 3 3 Flagellar motor switch protein FliM DUF349 PF03993.12 OAP54151.1 - 1.3e-06 28.6 0.1 1.3 9.4 0.0 3.3 3 0 0 3 3 3 3 Domain of Unknown Function (DUF349) DUF3887 PF13026.6 OAP54151.1 - 8.6e-05 23.3 0.1 2 9.3 0.0 3.2 1 1 2 3 3 3 2 Protein of unknown function (DUF3887) BBS2_C PF14782.6 OAP54151.1 - 9.2e-05 21.4 0.1 0.17 10.6 0.0 2.1 1 1 1 2 2 2 2 Ciliary BBSome complex subunit 2, C-terminal Ribosomal_L2_C PF03947.18 OAP54151.1 - 0.00049 20.3 0.0 2.9 8.1 0.0 3.3 3 0 0 3 3 3 1 Ribosomal Proteins L2, C-terminal domain ArsR PF09824.9 OAP54151.1 - 0.0018 17.9 0.4 5.8 6.5 0.0 3.2 1 1 2 3 3 3 1 ArsR transcriptional regulator DUF3467 PF11950.8 OAP54151.1 - 0.0021 18.2 0.1 19 5.6 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3467) Terminase_4 PF05119.12 OAP54151.1 - 0.0021 18.5 0.3 10 6.6 0.0 3.3 2 1 1 3 3 3 0 Phage terminase, small subunit RPW8 PF05659.11 OAP54151.1 - 0.003 17.3 0.8 1.3 8.7 0.4 2.9 1 1 1 2 2 2 1 Arabidopsis broad-spectrum mildew resistance protein RPW8 SUB1_ProdP9 PF18213.1 OAP54151.1 - 0.0035 17.1 0.6 0.63 9.9 0.1 3.0 1 1 2 3 3 3 1 SUB1 protease Prodomain ProdP9 RNA_pol_Rpb2_5 PF04567.17 OAP54151.1 - 0.0062 17.1 3.3 25 5.5 0.4 4.0 3 1 0 3 3 3 0 RNA polymerase Rpb2, domain 5 Globin PF00042.22 OAP54151.1 - 0.0067 17.0 0.0 12 6.5 0.0 3.2 1 1 2 3 3 3 0 Globin 2_5_RNA_ligase2 PF13563.6 OAP54151.1 - 0.011 15.7 0.0 2.1 8.2 0.0 2.2 1 1 0 2 2 2 0 2'-5' RNA ligase superfamily DUF4911 PF16256.5 OAP54151.1 - 0.014 15.3 0.6 28 4.8 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4911) PARP_reg PF02877.14 OAP54151.1 - 0.017 15.2 0.3 11 6.1 0.1 2.8 1 1 1 2 2 2 0 Poly(ADP-ribose) polymerase, regulatory domain FliS PF02561.14 OAP54151.1 - 0.025 14.9 2.4 27 5.1 0.1 3.2 3 0 0 3 3 3 0 Flagellar protein FliS Phage_int_SAM_3 PF14659.6 OAP54151.1 - 0.042 14.1 2.7 22 5.4 0.0 3.8 4 0 0 4 4 4 0 Phage integrase, N-terminal SAM-like domain YfdX PF10938.8 OAP54151.1 - 0.092 12.7 1.3 0.68 9.9 0.4 2.3 1 1 1 2 2 2 0 YfdX protein HhH-GPD PF00730.25 OAP54151.1 - 0.12 12.9 0.2 8.6 6.9 0.1 3.0 1 1 1 2 2 2 0 HhH-GPD superfamily base excision DNA repair protein F-112 PF09645.10 OAP54151.1 - 0.18 11.9 0.6 39 4.4 0.0 3.1 1 1 2 3 3 3 0 F-112 protein IL32 PF15225.6 OAP54151.1 - 0.48 10.8 1.8 75 3.8 0.1 3.2 1 1 1 3 3 3 0 Interleukin 32 DUF2478 PF10649.9 OAP54154.1 - 0.12 12.0 0.1 0.14 11.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2478) DUF3489 PF11994.8 OAP54154.1 - 0.14 12.2 0.1 0.27 11.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3489) Chromo PF00385.24 OAP54155.1 - 0.00012 21.9 0.1 0.00022 21.1 0.1 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain SelB-wing_2 PF09106.11 OAP54155.1 - 0.021 15.0 0.1 0.037 14.2 0.1 1.4 1 0 0 1 1 1 0 Elongation factor SelB, winged helix RT_RNaseH PF17917.1 OAP54156.1 - 0.0022 18.3 0.0 0.0078 16.5 0.0 1.9 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase PDZ_6 PF17820.1 OAP54157.1 - 0.057 13.3 0.0 1.3 9.0 0.0 2.4 2 0 0 2 2 2 0 PDZ domain MtrG PF04210.13 OAP54157.1 - 0.15 11.9 0.0 0.36 10.7 0.0 1.6 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit G Snapin_Pallidin PF14712.6 OAP54158.1 - 0.096 13.1 0.9 0.2 12.1 0.9 1.5 1 0 0 1 1 1 0 Snapin/Pallidin NDT80_PhoG PF05224.12 OAP54160.1 - 4.4e-26 92.2 0.0 5.1e-25 88.8 0.0 2.1 1 1 0 1 1 1 1 NDT80 / PhoG like DNA-binding family UIM PF02809.20 OAP54161.1 - 0.012 15.5 0.0 0.025 14.5 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin interaction motif F-box-like_2 PF13013.6 OAP54164.1 - 0.083 12.9 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 F-box-like domain Zn_clus PF00172.18 OAP54165.1 - 4.5e-08 33.1 9.2 6.9e-08 32.5 9.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ras PF00071.22 OAP54166.1 - 4.5e-07 29.6 0.0 4.6e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 Ras family PucR PF07905.11 OAP54166.1 - 0.09 13.1 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 Purine catabolism regulatory protein-like family HNH_2 PF13391.6 OAP54172.1 - 4.5e-07 29.9 0.0 1.3e-06 28.4 0.0 1.9 1 0 0 1 1 1 1 HNH endonuclease VIT1 PF01988.19 OAP54172.1 - 0.12 12.2 0.6 0.24 11.2 0.6 1.4 1 0 0 1 1 1 0 VIT family Ank_2 PF12796.7 OAP54173.1 - 2.5e-06 28.0 0.0 1e-05 26.0 0.0 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAP54173.1 - 3.7e-05 24.2 0.1 0.005 17.4 0.1 2.2 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAP54173.1 - 0.00084 19.6 0.0 0.074 13.6 0.0 2.6 3 0 0 3 3 3 1 Ankyrin repeat Sugar_tr PF00083.24 OAP54174.1 - 0.29 9.9 0.0 0.38 9.6 0.0 1.1 1 0 0 1 1 1 0 Sugar (and other) transporter FAD_binding_2 PF00890.24 OAP54175.1 - 0.045 12.8 0.0 0.067 12.3 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain PWWP PF00855.17 OAP54176.1 - 1.4e-13 51.0 0.0 1.4e-13 51.0 0.0 2.3 3 0 0 3 3 3 1 PWWP domain DUF2935 PF11155.8 OAP54176.1 - 0.086 13.2 0.1 0.15 12.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2935) DUF3770 PF12603.8 OAP54178.1 - 0.067 12.7 0.1 0.074 12.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3770) FtsX_ECD PF18075.1 OAP54178.1 - 0.081 13.6 0.2 0.16 12.6 0.1 1.5 1 1 0 1 1 1 0 FtsX extracellular domain Integrase_H2C2 PF17921.1 OAP54180.1 - 0.011 15.8 1.0 0.033 14.3 1.0 1.8 1 1 0 1 1 1 0 Integrase zinc binding domain zf-C2H2_jaz PF12171.8 OAP54182.1 - 0.0012 19.0 0.6 0.0033 17.7 0.6 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 OAP54182.1 - 0.0019 18.5 0.3 0.0046 17.4 0.3 1.7 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAP54182.1 - 0.0033 18.1 0.3 0.0091 16.8 0.3 1.8 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C3HC PF07967.13 OAP54182.1 - 0.0097 15.9 0.6 0.025 14.6 0.6 1.7 1 0 0 1 1 1 1 C3HC zinc finger-like zf-met PF12874.7 OAP54182.1 - 0.022 15.2 0.3 0.05 14.0 0.3 1.6 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-BED PF02892.15 OAP54182.1 - 0.055 13.5 0.1 0.1 12.6 0.1 1.5 1 0 0 1 1 1 0 BED zinc finger Nup160 PF11715.8 OAP54185.1 - 0.036 12.7 0.0 0.058 12.0 0.0 1.2 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Anoctamin PF04547.12 OAP54186.1 - 0.00053 18.9 0.0 0.00064 18.7 0.0 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel DUF3295 PF11702.8 OAP54187.1 - 0.00021 20.8 0.3 0.00025 20.5 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3295) HNH_2 PF13391.6 OAP54188.1 - 3.5e-10 39.9 0.0 7.8e-10 38.8 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease RdRP_3 PF00998.23 OAP54188.1 - 0.055 12.2 0.0 0.094 11.4 0.0 1.3 1 0 0 1 1 1 0 Viral RNA dependent RNA polymerase HNH_5 PF14279.6 OAP54188.1 - 0.13 12.2 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 HNH endonuclease Amidase PF01425.21 OAP54190.1 - 0.00073 18.6 0.0 0.0011 18.1 0.0 1.2 1 0 0 1 1 1 1 Amidase Chromo PF00385.24 OAP54190.1 - 0.086 12.8 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain p450 PF00067.22 OAP54193.1 - 6.2e-06 25.2 0.0 7.9e-06 24.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 IMPDH PF00478.25 OAP54195.1 - 4.2e-09 35.9 2.6 4.4e-08 32.5 0.8 2.1 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain MCM PF00493.23 OAP54195.1 - 0.087 11.9 0.2 0.13 11.3 0.2 1.2 1 0 0 1 1 1 0 MCM P-loop domain Inositol_P PF00459.25 OAP54197.1 - 4.7e-18 65.7 0.0 6.1e-18 65.3 0.0 1.1 1 0 0 1 1 1 1 Inositol monophosphatase family ATP-synt PF00231.19 OAP54198.1 - 2.3e-12 47.3 0.7 2.7e-12 47.0 0.7 1.0 1 0 0 1 1 1 1 ATP synthase THDPS_N_2 PF14805.6 OAP54200.1 - 0.13 12.5 0.0 0.27 11.5 0.0 1.5 1 0 0 1 1 1 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal ERp29 PF07749.12 OAP54201.1 - 0.11 13.4 0.0 0.2 12.6 0.0 1.4 1 0 0 1 1 1 0 Endoplasmic reticulum protein ERp29, C-terminal domain FAD_binding_3 PF01494.19 OAP54202.1 - 0.0019 17.5 0.3 0.0028 16.9 0.2 1.4 1 1 0 1 1 1 1 FAD binding domain zf-Mss51 PF13824.6 OAP54203.1 - 2.4e-06 27.5 0.3 4.4e-06 26.7 0.3 1.5 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 zf-C6H2 PF15801.5 OAP54203.1 - 0.2 12.0 2.0 9.5 6.6 0.1 2.3 1 1 1 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding NOA36 PF06524.12 OAP54207.1 - 1.8 7.8 5.5 2.4 7.4 5.5 1.1 1 0 0 1 1 1 0 NOA36 protein zinc_ribbon_2 PF13240.6 OAP54210.1 - 0.089 12.5 0.1 0.089 12.5 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain LexA_DNA_bind PF01726.16 OAP54210.1 - 0.12 12.1 0.0 0.34 10.7 0.0 1.8 1 0 0 1 1 1 0 LexA DNA binding domain Strabismus PF06638.11 OAP54211.1 - 0.14 10.8 0.8 0.18 10.4 0.8 1.1 1 0 0 1 1 1 0 Strabismus protein MAD PF05557.13 OAP54212.1 - 3e-05 22.6 0.0 3.5e-05 22.4 0.0 1.0 1 0 0 1 1 1 1 Mitotic checkpoint protein DNA_pol_B PF00136.21 OAP54214.1 - 1.3e-15 57.1 0.3 1.8e-15 56.6 0.3 1.3 1 1 0 1 1 1 1 DNA polymerase family B DNA_pol_B_2 PF03175.13 OAP54214.1 - 0.12 11.2 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral UPF0052 PF01933.18 OAP54214.1 - 0.17 11.1 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0052 PBP-Tp47_c PF14888.6 OAP54214.1 - 0.19 11.6 0.0 0.3 11.0 0.0 1.2 1 0 0 1 1 1 0 Penicillin-binding protein Tp47 domain C DUF349 PF03993.12 OAP54215.1 - 6.7e-08 32.7 0.6 0.14 12.5 0.0 3.1 1 1 2 3 3 3 3 Domain of Unknown Function (DUF349) TFA2_Winged_2 PF18121.1 OAP54215.1 - 3.1e-05 23.6 0.2 0.26 11.0 0.0 3.1 1 1 2 3 3 3 2 TFA2 Winged helix domain 2 Phage_int_SAM_3 PF14659.6 OAP54215.1 - 0.00012 22.3 2.4 0.3 11.4 0.1 3.4 2 1 0 3 3 3 2 Phage integrase, N-terminal SAM-like domain HEPN_DZIP3 PF18738.1 OAP54215.1 - 0.00016 21.4 0.1 3.1 7.6 0.0 3.0 1 1 2 3 3 3 2 DZIP3/ hRUL138-like HEPN MKT1_C PF12246.8 OAP54215.1 - 0.00082 18.7 1.6 0.84 8.8 0.2 2.9 1 1 2 3 3 3 2 Temperature dependent protein affecting M2 dsRNA replication LdpA_C PF12617.8 OAP54215.1 - 0.0016 18.1 0.3 2.5 7.7 0.0 2.6 1 1 2 3 3 3 2 Iron-Sulfur binding protein C terminal Ribosomal_L2_C PF03947.18 OAP54215.1 - 0.002 18.4 0.5 2.5 8.3 0.0 2.8 1 1 2 3 3 3 1 Ribosomal Proteins L2, C-terminal domain RNA_pol_Rpb2_5 PF04567.17 OAP54215.1 - 0.0045 17.5 2.9 8 7.1 0.1 3.2 2 1 1 3 3 3 0 RNA polymerase Rpb2, domain 5 DUF1572 PF07609.11 OAP54215.1 - 0.005 16.6 0.2 1.9 8.2 0.0 2.6 1 1 2 3 3 3 1 Protein of unknown function (DUF1572) DHC_N2 PF08393.13 OAP54215.1 - 0.0051 16.0 1.3 0.1 11.7 1.3 2.1 1 1 0 1 1 1 1 Dynein heavy chain, N-terminal region 2 THF_DHG_CYH_C PF02882.19 OAP54215.1 - 0.0071 15.7 0.5 1.2 8.5 0.1 2.6 2 1 1 3 3 3 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Transposase_28 PF04195.12 OAP54215.1 - 0.0093 16.2 0.0 3.6 7.9 0.0 3.0 3 0 0 3 3 3 1 Putative gypsy type transposon FliM PF02154.15 OAP54215.1 - 0.0095 15.8 0.4 5.3 6.9 0.0 3.0 1 1 2 3 3 3 1 Flagellar motor switch protein FliM YrpD PF15493.6 OAP54215.1 - 0.0099 15.8 0.2 0.022 14.6 0.1 1.6 1 1 0 1 1 1 1 Domain of unknown function, YrpD HhH-GPD PF00730.25 OAP54215.1 - 0.013 15.9 0.8 4.6 7.7 0.2 2.8 1 1 2 3 3 3 0 HhH-GPD superfamily base excision DNA repair protein Spc7_C2 PF15577.6 OAP54215.1 - 0.017 15.2 0.0 9.3 6.4 0.0 2.6 1 1 2 3 3 3 0 Spc7_C2 Ovate PF04844.13 OAP54215.1 - 0.021 14.8 0.2 4.6 7.3 0.1 2.6 2 1 0 2 2 2 0 Transcriptional repressor, ovate GLTP PF08718.11 OAP54215.1 - 0.023 14.9 0.0 9.3 6.5 0.0 2.6 1 1 1 2 2 2 0 Glycolipid transfer protein (GLTP) ExsD PF16806.5 OAP54215.1 - 0.045 13.7 2.5 0.12 12.3 1.0 1.8 1 1 1 2 2 2 0 Antiactivator protein ExsD PARP_reg PF02877.14 OAP54215.1 - 0.054 13.6 0.2 3.6 7.7 0.0 2.5 1 1 1 2 2 2 0 Poly(ADP-ribose) polymerase, regulatory domain Longin_2 PF18639.1 OAP54215.1 - 0.057 13.3 0.8 6.6 6.6 0.1 2.4 1 1 1 2 2 2 0 Yeast longin domain DUF4312 PF14189.6 OAP54215.1 - 0.057 13.4 0.3 2.2 8.3 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4312) LZ3wCH PF18517.1 OAP54215.1 - 0.06 13.5 6.2 6.7 6.9 0.2 3.2 3 0 0 3 3 3 0 Leucine zipper with capping helix domain DUF3467 PF11950.8 OAP54215.1 - 0.072 13.3 0.2 32 4.8 0.0 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF3467) F-112 PF09645.10 OAP54215.1 - 0.11 12.6 1.2 4.1 7.6 0.2 2.3 1 1 0 2 2 2 0 F-112 protein DUF4298 PF14131.6 OAP54215.1 - 0.11 12.4 0.1 26 4.9 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4298) AIP3 PF03915.13 OAP54216.1 - 1.1e-146 489.2 16.0 1.1e-146 489.2 16.0 1.6 2 0 0 2 2 2 1 Actin interacting protein 3 Med9 PF07544.13 OAP54216.1 - 0.02 15.0 4.9 4 7.6 0.1 4.7 3 1 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Lectin_N PF03954.14 OAP54216.1 - 0.45 10.3 2.9 0.36 10.6 0.2 2.3 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain K_channel_TID PF07941.11 OAP54216.1 - 5.5 7.5 18.4 0.52 10.8 9.4 2.7 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain DUF948 PF06103.11 OAP54216.1 - 6.3 7.1 17.3 28 5.0 1.9 5.3 4 1 1 5 5 5 0 Bacterial protein of unknown function (DUF948) CorA PF01544.18 OAP54216.1 - 9.9 5.4 8.6 27 3.9 2.9 2.8 3 0 0 3 3 3 0 CorA-like Mg2+ transporter protein Nop52 PF05997.12 OAP54217.1 - 7.3e-40 137.1 0.0 1e-39 136.6 0.0 1.1 1 0 0 1 1 1 1 Nucleolar protein,Nop52 DUF1295 PF06966.12 OAP54218.1 - 7.4e-37 127.1 8.1 1.1e-36 126.6 8.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PAS_9 PF13426.7 OAP54218.1 - 1.7e-17 63.5 0.0 5.7e-17 61.9 0.0 2.0 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 OAP54218.1 - 0.00035 20.6 0.0 0.0011 19.0 0.0 1.8 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.10 OAP54218.1 - 0.0067 16.7 0.0 0.038 14.2 0.0 2.3 2 0 0 2 2 2 1 PAS fold PqiA PF04403.13 OAP54218.1 - 0.033 14.0 2.6 0.067 13.0 2.6 1.4 1 0 0 1 1 1 0 Paraquat-inducible protein A ICMT PF04140.14 OAP54218.1 - 0.13 12.7 0.4 3.7 8.0 0.0 2.6 2 0 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Topoisom_bac PF01131.20 OAP54219.1 - 2.1e-106 356.4 0.0 2.5e-106 356.1 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 OAP54219.1 - 1.1e-18 67.3 0.0 6.7e-18 64.8 0.0 2.3 3 0 0 3 3 3 1 Toprim domain SE PF08491.10 OAP54219.1 - 0.061 12.4 0.0 1.5 7.8 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase DUF2985 PF11204.8 OAP54221.1 - 8.8e-36 121.9 0.9 8.8e-36 121.9 0.9 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2985) DUF4868 PF16162.5 OAP54221.1 - 0.18 11.7 0.4 0.29 11.0 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4868) Lig_chan PF00060.26 OAP54221.1 - 2.6 7.9 0.0 2.6 7.9 0.0 2.5 2 1 0 2 2 2 0 Ligand-gated ion channel Sen15 PF09631.10 OAP54222.1 - 2.7e-12 46.9 0.0 0.0025 18.1 0.0 3.2 3 0 0 3 3 3 3 Sen15 protein Vac_ImportDeg PF09783.9 OAP54223.1 - 1.8e-61 206.7 1.6 3.3e-61 205.8 1.6 1.4 1 0 0 1 1 1 1 Vacuolar import and degradation protein UBD PF16455.5 OAP54223.1 - 7.9e-37 125.7 0.0 1.6e-36 124.7 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-binding domain ubiquitin PF00240.23 OAP54223.1 - 0.00021 21.0 0.0 0.0004 20.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 OAP54223.1 - 0.082 12.7 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Mago_nashi PF02792.14 OAP54224.1 - 3.5e-66 221.7 0.1 4.7e-66 221.3 0.1 1.1 1 0 0 1 1 1 1 Mago nashi protein VitK2_biosynth PF02621.14 OAP54225.1 - 3.5e-05 23.5 0.0 0.0068 15.9 0.0 2.2 2 0 0 2 2 2 2 Menaquinone biosynthesis NMT1 PF09084.11 OAP54225.1 - 9e-05 22.5 0.0 0.0005 20.1 0.0 2.1 2 1 0 2 2 2 1 NMT1/THI5 like SBP_bac_3 PF00497.20 OAP54225.1 - 0.00073 19.0 0.0 0.0017 17.8 0.0 1.5 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Phosphonate-bd PF12974.7 OAP54225.1 - 0.0084 15.7 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein MFS_1 PF07690.16 OAP54226.1 - 6.9e-38 130.5 23.3 6.9e-38 130.5 23.3 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 OAP54226.1 - 4.2e-06 25.5 3.2 7.1e-06 24.7 3.2 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Staphopain_pro PF14731.6 OAP54226.1 - 0.11 12.5 0.2 0.17 11.9 0.2 1.2 1 0 0 1 1 1 0 Staphopain proregion OATP PF03137.20 OAP54226.1 - 1.8 6.8 23.8 0.58 8.4 10.5 3.4 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family FAD_binding_3 PF01494.19 OAP54227.1 - 6.8e-21 74.9 0.0 1e-20 74.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAP54227.1 - 1.1e-07 31.8 1.7 0.00051 19.7 0.5 2.3 1 1 0 2 2 2 2 FAD dependent oxidoreductase SE PF08491.10 OAP54227.1 - 0.00019 20.6 0.0 0.00064 18.9 0.0 1.7 1 1 0 1 1 1 1 Squalene epoxidase HI0933_like PF03486.14 OAP54227.1 - 0.0017 17.2 1.1 0.003 16.3 1.1 1.4 1 1 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.6 OAP54227.1 - 0.0052 17.0 0.9 0.043 14.0 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DUF5318 PF17249.2 OAP54227.1 - 0.021 14.6 0.0 0.046 13.5 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5318) NAD_binding_9 PF13454.6 OAP54227.1 - 0.029 14.3 0.7 0.37 10.8 0.1 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 OAP54227.1 - 0.18 11.0 6.6 3.4 6.8 6.6 2.4 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ADH_zinc_N PF00107.26 OAP54228.1 - 3.1e-21 75.7 0.0 5.8e-21 74.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAP54228.1 - 1e-20 73.6 0.4 1.7e-20 72.9 0.4 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 OAP54228.1 - 6.4e-09 35.6 0.0 1.1e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 OAP54228.1 - 6.7e-07 30.4 0.0 1.4e-06 29.4 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase p450 PF00067.22 OAP54230.1 - 1.5e-19 70.1 0.0 2.7e-18 66.0 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.18 OAP54231.1 - 3.9e-06 26.9 11.9 7.8e-06 25.9 11.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BES1_N PF05687.13 OAP54231.1 - 3.5 8.0 6.4 8.4 6.8 0.0 2.5 2 0 0 2 2 2 0 BES1/BZR1 plant transcription factor, N-terminal ketoacyl-synt PF00109.26 OAP54232.1 - 3e-75 253.1 0.0 5.9e-75 252.1 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.6 OAP54232.1 - 1.1e-58 198.9 0.0 2e-58 198.0 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 OAP54232.1 - 5.5e-47 160.0 0.0 1.3e-46 158.7 0.0 1.7 1 0 0 1 1 1 1 KR domain Condensation PF00668.20 OAP54232.1 - 4.3e-46 157.5 0.0 8.2e-46 156.6 0.0 1.4 1 0 0 1 1 1 1 Condensation domain Acyl_transf_1 PF00698.21 OAP54232.1 - 2.1e-43 149.0 0.0 4.4e-43 148.0 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 OAP54232.1 - 2.5e-31 108.1 0.0 9.6e-31 106.3 0.0 2.1 2 0 0 2 2 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 OAP54232.1 - 1.5e-19 70.6 0.0 4.1e-19 69.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 OAP54232.1 - 2.6e-15 56.9 0.0 5.6e-15 55.8 0.0 1.6 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_23 PF13489.6 OAP54232.1 - 3.1e-14 53.2 0.0 7e-14 52.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAP54232.1 - 4.2e-13 49.8 0.0 1.5e-12 48.0 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAP54232.1 - 7.6e-12 45.7 0.0 2.5e-11 44.1 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAP54232.1 - 2.1e-11 43.8 0.0 7.8e-11 42.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain adh_short PF00106.25 OAP54232.1 - 9.6e-09 35.0 0.0 2.4e-07 30.4 0.0 2.4 2 0 0 2 2 2 1 short chain dehydrogenase Ubie_methyltran PF01209.18 OAP54232.1 - 1.1e-06 28.1 0.0 2.3e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family adh_short_C2 PF13561.6 OAP54232.1 - 1.6e-06 27.9 0.0 4.1e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Thiolase_N PF00108.23 OAP54232.1 - 4.1e-06 26.3 0.1 8.4e-06 25.3 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain PP-binding PF00550.25 OAP54232.1 - 1.5e-05 25.3 0.5 6.5e-05 23.2 0.2 2.3 2 0 0 2 2 1 1 Phosphopantetheine attachment site Methyltransf_16 PF10294.9 OAP54232.1 - 0.00051 19.8 0.0 0.0012 18.6 0.0 1.5 1 0 0 1 1 1 1 Lysine methyltransferase RrnaAD PF00398.20 OAP54232.1 - 0.009 15.1 0.0 0.031 13.4 0.0 1.8 2 0 0 2 2 2 1 Ribosomal RNA adenine dimethylase Methyltransf_33 PF10017.9 OAP54232.1 - 0.051 12.7 0.0 0.11 11.6 0.0 1.5 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent FSH1 PF03959.13 OAP54233.1 - 5.1e-31 108.0 0.0 5.8e-31 107.8 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 OAP54233.1 - 6.4e-05 22.9 0.2 0.0085 15.9 0.1 2.4 2 1 0 2 2 2 2 Phospholipase/Carboxylesterase DUF4880 PF16220.5 OAP54233.1 - 2.7 7.9 5.5 5.6 6.9 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4880) ADH_N PF08240.12 OAP54234.1 - 6.4e-05 22.8 0.0 0.00011 22.0 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAP54234.1 - 7.7e-05 22.7 0.0 0.00016 21.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase p450 PF00067.22 OAP54235.1 - 4.4e-44 151.0 0.0 5.6e-44 150.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_3 PF01494.19 OAP54236.1 - 2.2e-26 92.9 0.1 3.2e-26 92.4 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 OAP54236.1 - 2e-07 30.5 2.5 3.7e-07 29.6 2.5 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 OAP54236.1 - 9.1e-07 28.4 3.6 2.1e-05 23.9 1.5 2.7 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAP54236.1 - 1e-05 25.7 1.0 2.5e-05 24.4 1.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 OAP54236.1 - 1.2e-05 24.4 0.6 0.0094 14.8 0.3 2.2 2 0 0 2 2 2 2 Tryptophan halogenase DAO PF01266.24 OAP54236.1 - 8.4e-05 22.3 7.3 0.00065 19.4 3.3 2.4 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 OAP54236.1 - 0.00012 22.5 0.4 0.0027 18.2 0.3 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 OAP54236.1 - 0.00034 20.1 1.5 0.0017 17.8 2.3 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 OAP54236.1 - 0.00096 18.5 1.2 0.0021 17.4 1.2 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OAP54236.1 - 0.001 18.2 0.2 0.0018 17.4 0.2 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.14 OAP54236.1 - 0.0018 17.0 1.1 0.0031 16.3 1.1 1.3 1 0 0 1 1 1 1 HI0933-like protein SE PF08491.10 OAP54236.1 - 0.0042 16.2 0.0 0.009 15.1 0.0 1.5 2 0 0 2 2 2 1 Squalene epoxidase Amino_oxidase PF01593.24 OAP54236.1 - 0.017 14.4 0.5 0.085 12.1 0.2 2.0 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Rossmann-like PF10727.9 OAP54236.1 - 0.026 14.4 0.6 0.085 12.7 0.6 1.9 1 0 0 1 1 1 0 Rossmann-like domain AlaDh_PNT_C PF01262.21 OAP54236.1 - 0.037 13.3 1.1 0.091 12.0 1.1 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 OAP54236.1 - 0.069 12.2 1.3 6.5 5.7 0.6 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein IlvN PF07991.12 OAP54236.1 - 0.075 12.6 0.2 0.16 11.6 0.2 1.5 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Thi4 PF01946.17 OAP54236.1 - 0.092 12.0 0.2 0.29 10.3 0.4 1.7 2 0 0 2 2 2 0 Thi4 family UDPG_MGDP_dh_N PF03721.14 OAP54236.1 - 0.18 11.4 0.6 0.29 10.7 0.6 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Oxidoreduct_C PF16490.5 OAP54236.1 - 0.18 11.5 0.1 1 9.0 0.0 1.9 2 0 0 2 2 2 0 Putative oxidoreductase C terminal domain NAD_binding_9 PF13454.6 OAP54236.1 - 0.64 10.0 3.9 7.9 6.4 0.3 2.7 3 0 0 3 3 3 0 FAD-NAD(P)-binding MFS_1 PF07690.16 OAP54237.1 - 2.7e-36 125.3 48.6 2.7e-36 125.3 48.6 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily Aldolase_II PF00596.21 OAP54238.1 - 1.7e-28 99.8 0.1 2.1e-28 99.5 0.1 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Fungal_trans PF04082.18 OAP54239.1 - 2.4e-27 95.6 0.0 4.4e-27 94.8 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_85 PF03644.13 OAP54239.1 - 0.076 12.4 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 85 Aldolase_II PF00596.21 OAP54240.1 - 1.8e-27 96.5 0.6 2.2e-27 96.2 0.6 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Adaptin_N PF01602.20 OAP54241.1 - 5.3e-94 315.6 9.6 8.6e-94 315.0 9.6 1.3 1 0 0 1 1 1 1 Adaptin N terminal region Coatamer_beta_C PF07718.12 OAP54241.1 - 1.9e-59 199.6 0.5 4.5e-59 198.4 0.5 1.7 1 0 0 1 1 1 1 Coatomer beta C-terminal region Coatomer_b_Cpla PF14806.6 OAP54241.1 - 1.3e-55 186.8 1.5 2.2e-55 186.1 0.1 2.2 2 0 0 2 2 2 1 Coatomer beta subunit appendage platform Cnd1 PF12717.7 OAP54241.1 - 1.2e-13 51.4 4.0 1.9e-09 37.8 0.1 3.0 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 OAP54241.1 - 9.9e-10 38.7 0.1 1.2e-05 25.5 0.0 5.8 3 1 3 6 6 6 4 HEAT repeats Coatomer_g_Cpla PF16381.5 OAP54241.1 - 8e-06 26.0 0.3 5.3e-05 23.3 0.0 2.6 3 0 0 3 3 3 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_EZ PF13513.6 OAP54241.1 - 0.0028 18.1 0.5 0.3 11.7 0.0 4.2 2 1 2 4 4 4 2 HEAT-like repeat HEAT PF02985.22 OAP54241.1 - 0.015 15.5 8.8 0.34 11.3 0.1 5.3 6 0 0 6 6 5 0 HEAT repeat HTH_44 PF14641.6 OAP54241.1 - 0.066 13.7 0.1 0.17 12.3 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix DNA-binding domain of SPT6 DUF5578 PF17741.1 OAP54241.1 - 0.093 12.1 3.7 3 7.2 0.1 2.8 1 1 1 2 2 2 0 Family of unknown function (DUF5578) DUF2326 PF10088.9 OAP54241.1 - 0.1 12.3 0.2 0.29 10.9 0.2 1.7 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2326) HEAT_PBS PF03130.16 OAP54241.1 - 0.17 12.7 0.5 1e+02 4.0 0.0 4.2 5 0 0 5 5 2 0 PBS lyase HEAT-like repeat NBD94 PF16830.5 OAP54241.1 - 0.34 11.3 5.4 0.24 11.8 1.5 2.6 2 0 0 2 2 2 0 Nucleotide-Binding Domain 94 of RH FAM117 PF15388.6 OAP54241.1 - 0.41 10.0 1.9 1.2 8.5 0.4 2.1 1 1 1 2 2 2 0 Protein Family FAM117 AP4E_app_platf PF14807.6 OAP54241.1 - 0.78 10.1 3.0 0.49 10.8 0.3 2.1 2 0 0 2 2 1 0 Adaptin AP4 complex epsilon appendage platform Arm PF00514.23 OAP54241.1 - 5.1 7.3 9.2 1.9 8.6 0.1 4.8 7 0 0 7 7 6 0 Armadillo/beta-catenin-like repeat AAA_33 PF13671.6 OAP54243.1 - 1.6e-12 47.8 0.0 2.5e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain SKI PF01202.22 OAP54243.1 - 1.8e-12 47.7 0.1 2.5e-12 47.2 0.1 1.2 1 0 0 1 1 1 1 Shikimate kinase AAA_18 PF13238.6 OAP54243.1 - 8.7e-09 36.0 0.1 5.1e-08 33.5 0.0 2.2 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.6 OAP54243.1 - 3.9e-06 27.3 0.1 1.3e-05 25.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.15 OAP54243.1 - 1.7e-05 24.8 0.0 3.7e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain Cytidylate_kin PF02224.18 OAP54243.1 - 4.2e-05 23.4 0.0 8.9e-05 22.3 0.0 1.5 2 0 0 2 2 1 1 Cytidylate kinase NACHT PF05729.12 OAP54243.1 - 0.0001 22.3 0.0 0.0004 20.3 0.0 1.9 1 1 1 2 2 2 1 NACHT domain AAA PF00004.29 OAP54243.1 - 0.0002 21.8 0.1 0.00038 20.9 0.0 1.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 OAP54243.1 - 0.00035 20.9 0.1 0.0008 19.7 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OAP54243.1 - 0.00037 20.9 0.0 0.00092 19.6 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OAP54243.1 - 0.00038 20.7 0.1 0.00062 20.0 0.1 1.7 1 1 0 1 1 1 1 AAA domain APS_kinase PF01583.20 OAP54243.1 - 0.00057 19.8 0.0 0.00077 19.4 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_14 PF13173.6 OAP54243.1 - 0.00059 19.9 0.0 0.0029 17.6 0.0 2.2 1 1 1 2 2 2 1 AAA domain AAA_25 PF13481.6 OAP54243.1 - 0.0007 19.2 0.1 0.0069 16.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 OAP54243.1 - 0.00072 19.4 0.3 0.047 13.4 0.1 2.2 1 1 1 2 2 2 1 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.22 OAP54243.1 - 0.00074 19.9 0.0 0.0017 18.7 0.0 1.6 2 0 0 2 2 1 1 RNA helicase AAA_5 PF07728.14 OAP54243.1 - 0.0025 17.8 0.0 0.0053 16.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) dNK PF01712.19 OAP54243.1 - 0.0041 17.0 0.1 0.48 10.2 0.0 2.2 1 1 0 2 2 2 1 Deoxynucleoside kinase Zeta_toxin PF06414.12 OAP54243.1 - 0.0049 16.2 0.1 0.0085 15.4 0.1 1.5 1 1 0 1 1 1 1 Zeta toxin RuvB_N PF05496.12 OAP54243.1 - 0.0063 16.3 0.0 0.01 15.6 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 OAP54243.1 - 0.0071 15.8 2.2 0.057 12.8 0.0 2.2 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI Cytidylate_kin2 PF13189.6 OAP54243.1 - 0.0074 16.4 0.1 0.032 14.4 0.0 2.0 1 1 1 2 2 2 1 Cytidylate kinase-like family ABC_tran PF00005.27 OAP54243.1 - 0.0077 16.8 0.0 0.014 15.9 0.0 1.6 1 1 0 1 1 1 1 ABC transporter AAA_30 PF13604.6 OAP54243.1 - 0.0085 15.8 0.1 0.013 15.2 0.1 1.5 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OAP54243.1 - 0.01 16.2 0.8 0.029 14.7 0.8 2.0 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.9 OAP54243.1 - 0.012 14.9 0.0 0.013 14.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Thermopsin PF05317.11 OAP54243.1 - 0.012 15.0 0.0 0.021 14.3 0.0 1.3 1 0 0 1 1 1 0 Thermopsin ATPase_2 PF01637.18 OAP54243.1 - 0.013 15.5 0.0 0.032 14.1 0.0 1.6 2 0 0 2 2 1 0 ATPase domain predominantly from Archaea NTPase_1 PF03266.15 OAP54243.1 - 0.015 15.3 0.0 0.044 13.7 0.0 1.7 2 0 0 2 2 2 0 NTPase PhoH PF02562.16 OAP54243.1 - 0.018 14.5 0.0 0.043 13.3 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein TsaE PF02367.17 OAP54243.1 - 0.018 15.0 0.1 0.04 13.9 0.0 1.6 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE CoaE PF01121.20 OAP54243.1 - 0.02 14.6 0.0 0.055 13.1 0.0 1.8 1 0 0 1 1 1 0 Dephospho-CoA kinase AAA_11 PF13086.6 OAP54243.1 - 0.027 14.3 0.6 0.19 11.5 0.6 2.0 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.22 OAP54243.1 - 0.029 13.5 0.0 0.097 11.8 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain ADK PF00406.22 OAP54243.1 - 0.039 14.0 0.7 0.73 9.9 0.7 2.3 1 1 0 1 1 1 0 Adenylate kinase PRK PF00485.18 OAP54243.1 - 0.047 13.4 0.0 0.087 12.6 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family KTI12 PF08433.10 OAP54243.1 - 0.047 13.1 0.6 0.097 12.1 0.6 1.5 1 1 0 1 1 1 0 Chromatin associated protein KTI12 AAA_23 PF13476.6 OAP54243.1 - 0.059 13.9 0.2 0.31 11.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain DNA_pol3_delta2 PF13177.6 OAP54243.1 - 0.064 13.0 0.5 0.17 11.6 0.0 1.9 2 1 0 2 2 2 0 DNA polymerase III, delta subunit tRNA_lig_kinase PF08303.11 OAP54243.1 - 0.067 13.3 0.1 0.2 11.8 0.0 2.0 2 1 0 2 2 1 0 tRNA ligase kinase domain IPPT PF01715.17 OAP54243.1 - 0.087 12.6 0.5 0.15 11.8 0.5 1.5 1 1 0 1 1 1 0 IPP transferase PduV-EutP PF10662.9 OAP54243.1 - 0.12 12.1 0.0 0.28 10.9 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ATPase PF06745.13 OAP54243.1 - 0.14 11.5 0.4 0.64 9.3 0.0 2.1 2 1 0 2 2 2 0 KaiC Vps26 PF03643.15 OAP54244.1 - 1.8e-129 430.6 0.5 2e-129 430.4 0.5 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 OAP54244.1 - 0.00013 22.0 0.8 1.2 9.2 0.0 3.4 2 1 2 4 4 4 2 Arrestin (or S-antigen), N-terminal domain DCB PF16213.5 OAP54245.1 - 1.2e-41 142.3 0.5 1.2e-41 142.3 0.5 2.2 2 0 0 2 2 2 1 Dimerisation and cyclophilin-binding domain of Mon2 Sec7_N PF12783.7 OAP54245.1 - 1.3e-20 73.9 4.0 1.7e-20 73.5 0.7 2.9 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Mon2_C PF16206.5 OAP54245.1 - 7.5e-08 31.0 0.5 7.1e-07 27.8 0.4 2.3 2 0 0 2 2 2 1 C-terminal region of Mon2 protein Dak2 PF02734.17 OAP54245.1 - 8.4e-05 22.5 2.3 0.0001 22.2 0.3 2.2 2 0 0 2 2 2 1 DAK2 domain DUF1981 PF09324.10 OAP54245.1 - 0.0092 15.8 0.1 3.6 7.5 0.0 4.2 3 1 1 4 4 4 1 Domain of unknown function (DUF1981) Ipi1_N PF12333.8 OAP54245.1 - 0.22 12.1 2.7 4.1 8.0 1.1 4.0 2 2 1 3 3 3 0 Rix1 complex component involved in 60S ribosome maturation HEAT PF02985.22 OAP54245.1 - 2.8 8.4 4.8 4.7 7.7 0.1 4.0 3 0 0 3 3 3 0 HEAT repeat SpoIISA_toxin PF14171.6 OAP54246.1 - 0.57 9.8 1.7 0.94 9.1 1.7 1.3 1 0 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system CFEM PF05730.11 OAP54247.1 - 0.0024 17.9 3.3 0.0024 17.9 3.3 2.8 2 1 0 2 2 2 1 CFEM domain UQ_con PF00179.26 OAP54248.1 - 1.2e-16 60.6 0.0 1.3e-16 60.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Complex1_LYR PF05347.15 OAP54249.1 - 0.0016 18.5 0.0 0.0016 18.5 0.0 2.9 2 1 1 3 3 3 1 Complex 1 protein (LYR family) Glucan_synthase PF02364.15 OAP54249.1 - 0.42 8.7 2.1 0.21 9.7 0.1 1.4 2 0 0 2 2 2 0 1,3-beta-glucan synthase component Cid2 PF09774.9 OAP54250.1 - 3.8e-49 167.2 0.0 4.4e-49 167.0 0.0 1.0 1 0 0 1 1 1 1 Caffeine-induced death protein 2 Fe_hyd_lg_C PF02906.14 OAP54251.1 - 3.7e-56 190.5 0.0 7.3e-56 189.5 0.0 1.5 1 1 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Sugar_tr PF00083.24 OAP54252.1 - 7.3e-110 367.9 16.1 9.1e-110 367.6 16.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP54252.1 - 4.5e-28 98.2 21.1 4.5e-28 98.2 21.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily LacY_symp PF01306.19 OAP54252.1 - 0.00013 20.9 5.7 0.00033 19.6 1.2 2.3 2 0 0 2 2 2 2 LacY proton/sugar symporter Halogen_Hydrol PF10112.9 OAP54252.1 - 0.1 12.6 0.2 24 4.9 0.0 2.8 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein MFS_1_like PF12832.7 OAP54252.1 - 0.87 8.4 17.9 5.1 5.9 12.3 3.3 2 1 0 2 2 2 0 MFS_1 like family Fapy_DNA_glyco PF01149.24 OAP54253.1 - 6.3e-33 113.8 0.2 2.4e-32 112.0 0.1 1.9 2 0 0 2 2 2 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.14 OAP54253.1 - 3.3e-22 78.3 0.0 7e-22 77.2 0.0 1.5 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain FbpA PF05833.11 OAP54253.1 - 0.0015 17.4 0.0 0.0032 16.3 0.0 1.5 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) Mitofilin PF09731.9 OAP54253.1 - 1.4 7.6 29.0 2.1 7.1 29.0 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein SAPS PF04499.15 OAP54253.1 - 3.5 6.3 5.7 4.3 6.0 5.7 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF4778 PF16008.5 OAP54253.1 - 4.6 7.2 8.6 7.9 6.4 8.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) MFS_1 PF07690.16 OAP54254.1 - 8.4e-09 34.8 39.6 8.4e-09 34.8 39.6 2.4 1 1 1 2 2 2 1 Major Facilitator Superfamily FSH1 PF03959.13 OAP54255.1 - 1.3e-67 227.6 0.0 1.6e-67 227.3 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 OAP54255.1 - 0.0088 16.7 1.7 0.018 15.7 1.7 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAP54255.1 - 0.026 13.8 0.0 0.094 12.0 0.0 1.8 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Thioesterase PF00975.20 OAP54255.1 - 0.065 13.3 0.2 0.31 11.1 0.1 1.9 2 0 0 2 2 2 0 Thioesterase domain Abhydrolase_2 PF02230.16 OAP54255.1 - 0.1 12.4 0.5 14 5.4 0.1 2.9 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase KH_6 PF15985.5 OAP54256.1 - 8.5e-18 64.4 0.0 1.5e-17 63.6 0.0 1.4 1 0 0 1 1 1 1 KH domain HSP70 PF00012.20 OAP54257.1 - 1.9e-79 267.5 3.5 3e-79 266.8 1.1 1.9 2 0 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 OAP54257.1 - 1.7e-07 30.4 0.1 2.7e-07 29.7 0.1 1.3 1 0 0 1 1 1 1 MreB/Mbl protein PilM_2 PF11104.8 OAP54257.1 - 6.5e-05 22.1 0.2 0.0081 15.2 0.1 2.3 2 0 0 2 2 2 2 Type IV pilus assembly protein PilM; FAM176 PF14851.6 OAP54257.1 - 0.026 14.2 0.4 0.062 13.0 0.4 1.6 1 0 0 1 1 1 0 FAM176 family CENP-B_dimeris PF09026.10 OAP54257.1 - 0.53 10.7 8.6 1.4 9.4 8.6 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DNA_pol_phi PF04931.13 OAP54257.1 - 2 6.4 6.3 3.6 5.6 6.3 1.3 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 OAP54257.1 - 6.6 6.0 9.4 11 5.3 9.4 1.2 1 0 0 1 1 1 0 NOA36 protein Cwf_Cwc_15 PF04889.12 OAP54257.1 - 9.9 5.8 11.1 0.38 10.5 4.9 1.7 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein MFS_1 PF07690.16 OAP54258.1 - 4.8e-34 117.8 29.9 7.1e-23 81.1 17.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 OAP54258.1 - 2.5e-07 29.9 9.1 0.00033 19.6 0.7 2.4 2 1 0 2 2 2 2 MFS_1 like family Sugar_tr PF00083.24 OAP54258.1 - 6.3e-07 28.6 17.1 0.00025 20.0 11.0 3.4 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.6 OAP54258.1 - 5.3e-05 22.0 19.1 0.026 13.1 5.3 3.2 1 1 2 3 3 3 2 MFS/sugar transport protein UNC-93 PF05978.16 OAP54258.1 - 3.6 7.3 7.3 0.12 12.0 0.3 2.1 3 0 0 3 3 3 0 Ion channel regulatory protein UNC-93 DUF998 PF06197.13 OAP54258.1 - 4.4 6.9 20.0 0.67 9.5 11.0 3.3 2 2 0 2 2 2 0 Protein of unknown function (DUF998) ADH_zinc_N PF00107.26 OAP54260.1 - 6.1e-18 65.0 0.2 1.1e-17 64.3 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAP54260.1 - 1.7e-14 55.0 0.0 4.3e-14 53.7 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAP54260.1 - 2.2e-06 27.5 0.0 4.7e-06 26.4 0.0 1.6 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ELFV_dehydrog PF00208.21 OAP54260.1 - 0.015 15.1 0.1 0.065 12.9 0.0 1.9 2 0 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase PSI PF01437.25 OAP54262.1 - 0.0036 17.8 10.6 0.0057 17.2 10.6 1.5 1 1 0 1 1 1 1 Plexin repeat HemY_N PF07219.13 OAP54262.1 - 0.017 15.3 0.7 0.027 14.7 0.7 1.3 1 0 0 1 1 1 0 HemY protein N-terminus Yip1 PF04893.17 OAP54262.1 - 0.037 13.8 0.5 0.047 13.4 0.5 1.1 1 0 0 1 1 1 0 Yip1 domain Metallophos PF00149.28 OAP54263.1 - 8.3e-09 36.2 2.7 1.8e-08 35.2 2.7 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF2457 PF10446.9 OAP54263.1 - 0.09 11.9 8.8 0.15 11.2 8.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) PBP1_TM PF14812.6 OAP54263.1 - 0.28 11.6 9.5 4.2 7.8 0.5 3.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal GEN1_C PF18380.1 OAP54263.1 - 5.6 7.9 6.6 8.8 7.3 2.2 2.7 2 0 0 2 2 2 0 Holliday junction resolvase Gen1 C-terminal domain Fungal_trans PF04082.18 OAP54264.1 - 5.8e-20 71.4 0.4 8.8e-20 70.8 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP54264.1 - 2.5e-08 33.9 9.1 5e-08 32.9 9.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAP54265.1 - 8e-14 51.3 0.0 1.6e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP54265.1 - 8.1e-09 35.5 12.0 1.4e-08 34.7 12.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Trimer_CC PF08954.11 OAP54265.1 - 0.00042 19.8 0.0 0.0013 18.3 0.0 1.8 1 0 0 1 1 1 1 Trimerisation motif DUF4078 PF13300.6 OAP54265.1 - 0.13 12.6 0.1 0.3 11.4 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4078) zf-C2H2 PF00096.26 OAP54266.1 - 0.37 11.3 2.6 1.4 9.5 2.6 2.1 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2 PF00096.26 OAP54267.1 - 0.32 11.5 5.7 0.35 11.4 3.7 2.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type Thiolase_N PF00108.23 OAP54268.1 - 1.1e-12 48.0 0.0 3.7e-11 42.9 0.0 2.6 2 1 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 OAP54268.1 - 8.2e-12 44.9 0.6 1.1e-10 41.2 0.0 2.9 2 1 0 3 3 3 1 Thiolase, C-terminal domain ACP_syn_III PF08545.10 OAP54268.1 - 4.2e-05 23.3 0.0 0.0053 16.6 0.0 2.5 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.26 OAP54268.1 - 0.013 15.1 0.2 0.5 9.9 0.1 2.5 2 1 1 3 3 3 0 Beta-ketoacyl synthase, N-terminal domain SpoVAD PF07451.11 OAP54268.1 - 0.021 13.5 0.1 0.078 11.7 0.0 1.8 2 0 0 2 2 2 0 Stage V sporulation protein AD (SpoVAD) Ketoacyl-synt_C PF02801.22 OAP54268.1 - 0.051 13.6 0.1 1.1 9.3 0.0 2.7 2 0 0 2 2 2 0 Beta-ketoacyl synthase, C-terminal domain DUF3208 PF11482.8 OAP54268.1 - 0.11 12.9 0.0 0.3 11.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3208) Fungal_trans PF04082.18 OAP54272.1 - 6.6e-11 41.7 0.2 1.1e-10 41.1 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain IDO PF01231.18 OAP54273.1 - 1.8e-152 508.1 0.0 2e-152 508.0 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase AA_permease_2 PF13520.6 OAP54274.1 - 7.8e-45 153.5 61.8 9.8e-45 153.1 61.8 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAP54274.1 - 3.7e-19 68.7 51.9 5.3e-19 68.2 51.9 1.1 1 0 0 1 1 1 1 Amino acid permease DUF3445 PF11927.8 OAP54275.1 - 2.6e-56 190.8 0.0 4.4e-56 190.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Fungal_trans_2 PF11951.8 OAP54275.1 - 5.8e-45 153.7 4.7 7.2e-45 153.4 4.7 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain GalP_UDP_tr_C PF02744.17 OAP54275.1 - 0.023 14.4 0.0 7.6 6.2 0.0 2.7 2 1 0 2 2 2 0 Galactose-1-phosphate uridyl transferase, C-terminal domain ADH_N PF08240.12 OAP54276.1 - 3e-22 78.6 1.5 5.8e-22 77.6 1.5 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAP54276.1 - 2.3e-13 50.2 0.2 4.8e-13 49.2 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 OAP54276.1 - 9.6e-07 28.3 0.1 1.7e-06 27.5 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 OAP54276.1 - 0.00018 20.9 0.4 0.00029 20.3 0.4 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_11 PF08241.12 OAP54276.1 - 0.017 15.7 0.0 0.056 14.1 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Oxidored_nitro PF00148.19 OAP54276.1 - 0.076 11.7 0.0 0.1 11.3 0.0 1.1 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase ELFV_dehydrog PF00208.21 OAP54276.1 - 0.1 12.3 0.1 0.17 11.6 0.1 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 3HCDH_N PF02737.18 OAP54276.1 - 0.12 12.3 0.1 0.18 11.7 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PhyH PF05721.13 OAP54277.1 - 7.5e-18 65.6 0.0 9.6e-18 65.2 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) CorA PF01544.18 OAP54278.1 - 4.6e-10 39.3 5.5 1.1e-09 38.0 5.5 1.6 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Abhydrolase_1 PF00561.20 OAP54279.1 - 7.8e-13 48.7 0.0 1.4e-09 38.0 0.0 2.5 2 1 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAP54279.1 - 1.1e-07 31.4 0.0 2.3e-07 30.3 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OAP54279.1 - 3.9e-07 30.9 0.1 7.8e-07 29.9 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family CorA PF01544.18 OAP54279.1 - 4.6e-05 22.9 1.2 4.6e-05 22.9 1.2 1.6 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein AXE1 PF05448.12 OAP54279.1 - 5.1e-05 22.1 0.0 0.066 11.9 0.1 2.8 2 1 0 2 2 2 2 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.21 OAP54279.1 - 0.002 17.6 0.2 0.058 12.9 0.0 2.3 2 0 0 2 2 2 1 Prolyl oligopeptidase family BAAT_C PF08840.11 OAP54279.1 - 0.0072 16.3 0.0 0.015 15.3 0.0 1.4 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal EMP70 PF02990.16 OAP54279.1 - 0.017 13.8 0.4 0.026 13.2 0.4 1.1 1 0 0 1 1 1 0 Endomembrane protein 70 BatD PF13584.6 OAP54279.1 - 0.056 12.2 0.1 0.087 11.6 0.1 1.2 1 0 0 1 1 1 0 Oxygen tolerance DLH PF01738.18 OAP54279.1 - 0.094 12.3 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Dienelactone hydrolase family BacA PF02673.18 OAP54279.1 - 0.096 12.4 0.2 0.19 11.4 0.2 1.4 1 0 0 1 1 1 0 Bacitracin resistance protein BacA LRR_5 PF13306.6 OAP54280.1 - 3.5e-05 23.7 3.7 0.0036 17.3 0.0 2.5 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) Recep_L_domain PF01030.24 OAP54280.1 - 0.00074 19.6 6.6 1.5 9.0 0.0 3.8 1 1 3 4 4 4 1 Receptor L domain Ecm33 PF12454.8 OAP54280.1 - 0.00075 19.6 0.6 0.004 17.3 0.6 2.4 1 1 0 1 1 1 1 GPI-anchored cell wall organization protein SR-25 PF10500.9 OAP54280.1 - 2.3 7.7 4.6 3.2 7.3 4.6 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein HhH-GPD PF00730.25 OAP54281.1 - 5e-14 52.7 0.0 8.4e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein UCR_14kD PF02271.16 OAP54282.1 - 5.1e-44 148.3 0.0 6e-44 148.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Mito_carr PF00153.27 OAP54283.1 - 1.4e-66 220.5 4.5 1.7e-23 82.3 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Tcf25 PF04910.14 OAP54284.1 - 3.9e-78 263.0 0.1 5.5e-78 262.5 0.1 1.2 1 0 0 1 1 1 1 Transcriptional repressor TCF25 PP2C PF00481.21 OAP54285.1 - 2.6e-42 145.2 0.0 4.3e-42 144.5 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 OAP54285.1 - 0.00029 20.5 0.0 0.00056 19.6 0.0 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 OAP54285.1 - 0.017 15.0 0.0 2.1 8.2 0.0 2.5 2 0 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) ALG11_N PF15924.5 OAP54287.1 - 3.5e-29 102.4 0.1 7.7e-29 101.2 0.1 1.5 2 0 0 2 2 2 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 OAP54287.1 - 4.1e-21 75.3 0.0 6.3e-21 74.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 OAP54287.1 - 7.4e-07 29.7 0.0 1.5e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 OAP54287.1 - 0.014 15.4 0.1 0.036 14.1 0.0 1.7 2 0 0 2 2 2 0 Glycosyltransferase Family 4 AAA_5 PF07728.14 OAP54287.1 - 0.069 13.1 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Glyco_trans_4_4 PF13579.6 OAP54287.1 - 0.11 12.9 0.0 3 8.3 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferase 4-like domain UQ_con PF00179.26 OAP54288.1 - 2.9e-48 163.1 0.0 3.2e-48 162.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OAP54288.1 - 3.3e-05 23.6 0.0 0.00032 20.4 0.0 2.1 1 1 1 2 2 2 1 Prokaryotic E2 family B RWD PF05773.22 OAP54288.1 - 0.18 12.1 1.7 0.3 11.4 1.7 1.7 1 1 0 1 1 1 0 RWD domain Asn_synthase PF00733.21 OAP54289.1 - 3.2e-92 310.0 0.0 6.3e-89 299.1 0.0 2.1 1 1 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.6 OAP54289.1 - 4.2e-37 126.8 0.0 6.9e-37 126.1 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 OAP54289.1 - 5e-28 98.0 0.0 9.2e-28 97.1 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 OAP54289.1 - 3.3e-07 30.0 0.0 8.4e-07 28.7 0.0 1.6 2 0 0 2 2 2 1 Aluminium induced protein NAD_synthase PF02540.17 OAP54289.1 - 0.01 15.0 0.1 0.03 13.4 0.1 1.7 1 1 1 2 2 2 0 NAD synthase Porin_3 PF01459.22 OAP54290.1 - 1.2e-67 228.3 10.7 3.3e-67 226.8 10.7 1.6 1 1 0 1 1 1 1 Eukaryotic porin DnaJ PF00226.31 OAP54291.1 - 7.1e-20 70.9 0.5 7.1e-20 70.9 0.5 2.0 3 0 0 3 3 3 1 DnaJ domain Branch PF02485.21 OAP54291.1 - 0.11 11.9 0.0 0.28 10.7 0.0 1.6 2 0 0 2 2 2 0 Core-2/I-Branching enzyme Adeno_E3 PF06040.11 OAP54291.1 - 0.14 12.3 0.0 11 6.2 0.0 2.3 2 0 0 2 2 2 0 Adenovirus E3 protein Peptidase_M24 PF00557.24 OAP54292.1 - 6.2e-42 143.7 0.0 8.2e-42 143.3 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF3994 PF13159.6 OAP54292.1 - 0.038 14.5 0.1 0.14 12.7 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3994) PGA2 PF07543.12 OAP54292.1 - 0.12 12.3 2.6 0.33 10.9 2.6 1.7 1 0 0 1 1 1 0 Protein trafficking PGA2 Chorismate_synt PF01264.21 OAP54293.1 - 5.1e-141 469.1 0.0 5.9e-141 468.9 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase Kelch_5 PF13854.6 OAP54294.1 - 0.022 14.7 0.1 4.9 7.2 0.0 3.2 3 0 0 3 3 3 0 Kelch motif Kelch_4 PF13418.6 OAP54294.1 - 0.18 11.9 7.2 6.9 6.8 0.1 4.3 5 0 0 5 5 5 0 Galactose oxidase, central domain Ribonuc_red_lgC PF02867.15 OAP54295.1 - 8.9e-190 631.7 0.0 1.2e-189 631.2 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 OAP54295.1 - 2.6e-24 85.0 0.0 6.2e-24 83.8 0.0 1.7 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 OAP54295.1 - 6.9e-18 65.0 0.0 1.4e-17 64.1 0.0 1.5 1 0 0 1 1 1 1 ATP cone domain Omp_AT PF11557.8 OAP54296.1 - 0.15 11.0 0.1 14 4.5 0.0 2.3 2 0 0 2 2 2 0 Solitary outer membrane autotransporter beta-barrel domain SAP PF02037.27 OAP54297.1 - 6.2e-10 38.6 0.1 1.4e-09 37.4 0.1 1.6 1 0 0 1 1 1 1 SAP domain Asp PF00026.23 OAP54298.1 - 5.6e-71 239.5 9.0 7.7e-71 239.1 9.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OAP54298.1 - 8.5e-10 39.2 1.3 8.5e-10 39.2 1.3 3.3 3 1 0 3 3 3 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 OAP54298.1 - 0.00011 22.8 0.2 0.1 13.3 0.0 3.0 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 OAP54298.1 - 0.0041 17.7 1.4 2.3 8.8 0.0 3.1 3 0 0 3 3 3 2 gag-polyprotein putative aspartyl protease adh_short_C2 PF13561.6 OAP54299.1 - 2.5e-49 167.9 1.7 3e-49 167.7 1.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP54299.1 - 9.3e-46 155.8 1.9 1.2e-45 155.4 1.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAP54299.1 - 2.1e-06 27.8 1.1 3.3e-05 23.9 1.1 2.1 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 OAP54299.1 - 0.00011 21.4 0.5 0.00015 20.9 0.5 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 OAP54299.1 - 0.0011 18.5 0.3 0.0026 17.2 0.2 1.8 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family DFP PF04127.15 OAP54299.1 - 0.011 15.6 0.4 0.017 15.0 0.4 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein RmlD_sub_bind PF04321.17 OAP54299.1 - 0.084 12.0 0.1 0.14 11.2 0.1 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain FMN_red PF03358.15 OAP54299.1 - 0.14 11.9 0.4 0.33 10.7 0.2 1.6 2 0 0 2 2 2 0 NADPH-dependent FMN reductase Aa_trans PF01490.18 OAP54300.1 - 3.1e-77 260.0 28.2 3.7e-77 259.8 28.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein TssN PF17555.2 OAP54300.1 - 0.5 9.7 5.4 0.7 9.2 1.4 2.5 2 1 0 2 2 2 0 Type VI secretion system, TssN Phage_holin_2_1 PF04971.12 OAP54300.1 - 0.52 10.4 2.8 2.1 8.4 0.1 3.2 3 0 0 3 3 3 0 Bacteriophage P21 holin S CAML PF14963.6 OAP54302.1 - 0.32 11.1 8.1 0.11 12.6 1.3 2.0 1 1 0 2 2 2 0 Calcium signal-modulating cyclophilin ligand YCF90 PF17088.5 OAP54303.1 - 0.06 12.7 0.0 0.062 12.6 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family CTP_transf_like PF01467.26 OAP54304.1 - 0.0012 19.0 0.0 0.11 12.7 0.0 2.3 2 0 0 2 2 2 2 Cytidylyltransferase-like AA_permease_2 PF13520.6 OAP54305.1 - 3e-39 135.1 14.6 3e-39 135.1 14.6 1.6 2 0 0 2 2 2 1 Amino acid permease Ank_2 PF12796.7 OAP54306.1 - 9.3e-59 196.0 16.5 8.6e-08 32.7 1.2 11.8 5 4 4 11 11 11 10 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAP54306.1 - 7.3e-38 128.5 32.0 0.00072 20.1 0.1 15.6 9 4 8 17 17 17 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAP54306.1 - 3.6e-27 91.4 46.6 2.1 9.2 0.1 22.2 24 0 0 24 24 24 7 Ankyrin repeat Ank_5 PF13857.6 OAP54306.1 - 3e-19 68.8 30.8 0.022 15.1 0.0 14.9 8 4 9 17 17 17 6 Ankyrin repeats (many copies) Clr5 PF14420.6 OAP54306.1 - 2.9e-11 43.4 1.3 6.1e-11 42.4 1.3 1.5 1 0 0 1 1 1 1 Clr5 domain Ank PF00023.30 OAP54306.1 - 3e-08 33.7 50.3 0.53 10.8 0.0 17.3 18 1 1 19 19 19 3 Ankyrin repeat PBP1_TM PF14812.6 OAP54306.1 - 0.21 12.0 1.3 0.48 10.8 1.3 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Shigella_OspC PF06128.11 OAP54306.1 - 0.23 11.1 0.2 1.1e+02 2.3 0.0 3.8 4 1 1 5 5 5 0 Shigella flexneri OspC protein NOA36 PF06524.12 OAP54306.1 - 0.4 9.9 4.1 0.72 9.1 4.1 1.3 1 0 0 1 1 1 0 NOA36 protein CCDC154 PF15450.6 OAP54308.1 - 0.0014 17.2 0.3 0.0021 16.7 0.3 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 154 DUF5332 PF17266.2 OAP54308.1 - 0.24 11.1 1.0 0.58 9.8 0.4 1.9 1 1 1 2 2 2 0 Family of unknown function (DUF5332) Pkinase PF00069.25 OAP54309.1 - 3.1e-15 56.3 0.0 4.2e-14 52.5 0.0 2.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP54309.1 - 0.00021 20.7 0.0 0.0015 17.9 0.0 2.2 2 1 0 2 2 2 1 Protein tyrosine kinase Ribosomal_60s PF00428.19 OAP54310.1 - 1.5e-26 92.8 12.8 1.9e-26 92.5 12.8 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Cytomega_UL84 PF06284.11 OAP54310.1 - 0.026 13.0 3.1 0.033 12.7 3.1 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein Phage_holin_6_1 PF09682.10 OAP54310.1 - 0.1 13.0 1.8 0.15 12.5 0.1 1.8 2 0 0 2 2 2 0 Bacteriophage holin of superfamily 6 (Holin_LLH) DUF3824 PF12868.7 OAP54310.1 - 1.7 9.3 5.9 2.3 8.9 5.9 1.1 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) Fe-ADH PF00465.19 OAP54311.1 - 4.1e-67 226.6 0.0 5.4e-67 226.2 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 OAP54311.1 - 1.9e-12 47.5 0.0 1.1e-05 25.3 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase HAD_SAK_2 PF18143.1 OAP54311.1 - 0.052 13.9 0.0 0.2 11.9 0.0 2.0 2 0 0 2 2 2 0 HAD domain in Swiss Army Knife RNA repair proteins Acyl_transf_3 PF01757.22 OAP54312.1 - 1.9e-26 93.0 32.7 2.7e-26 92.5 32.7 1.2 1 0 0 1 1 1 1 Acyltransferase family RTA1 PF04479.13 OAP54313.1 - 2.9e-71 239.4 3.6 2.9e-71 239.4 3.6 1.9 1 1 1 2 2 2 1 RTA1 like protein zf-C2H2 PF00096.26 OAP54315.1 - 1.9e-12 46.9 14.1 2.3e-06 27.7 2.3 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OAP54315.1 - 2.6e-12 46.6 9.3 1.8e-07 31.3 0.2 3.7 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 OAP54315.1 - 3.1e-08 33.8 11.8 0.00073 20.2 1.4 4.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 OAP54315.1 - 3.7e-08 33.2 5.2 0.00046 20.1 0.3 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OAP54315.1 - 1.1e-05 25.5 0.6 0.33 11.3 0.2 3.6 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OAP54315.1 - 0.00025 21.3 5.1 0.012 15.9 0.3 3.8 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 OAP54315.1 - 0.02 14.6 5.4 1.1 9.1 0.5 3.4 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-Di19 PF05605.12 OAP54315.1 - 0.091 13.1 1.4 0.18 12.1 1.4 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2HE PF16278.5 OAP54315.1 - 0.24 11.9 2.1 7.9 7.0 0.3 2.6 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger LIM PF00412.22 OAP54315.1 - 0.66 10.3 3.1 23 5.3 0.1 2.4 1 1 1 2 2 2 0 LIM domain zf-BED PF02892.15 OAP54315.1 - 0.88 9.6 3.2 26 4.9 3.2 2.4 1 1 0 1 1 1 0 BED zinc finger C5HCH PF17982.1 OAP54315.1 - 2.5 8.3 6.7 9.6 6.5 1.1 2.6 1 1 1 2 2 2 0 NSD Cys-His rich domain FYVE PF01363.21 OAP54315.1 - 2.6 8.2 5.0 5 7.3 5.0 1.5 1 0 0 1 1 1 0 FYVE zinc finger Pkinase PF00069.25 OAP54316.1 - 1.6e-27 96.5 0.0 2e-27 96.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP54316.1 - 2.4e-14 53.2 0.0 3.2e-14 52.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAP54316.1 - 9.7e-07 27.9 0.0 1.4e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase adh_short_C2 PF13561.6 OAP54318.1 - 2.4e-42 145.1 0.2 2.9e-42 144.8 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP54318.1 - 3.9e-34 117.8 0.0 5e-34 117.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAP54318.1 - 3.6e-09 36.8 0.1 1.2e-08 35.1 0.0 1.7 2 0 0 2 2 2 1 KR domain DAHP_snth_FXD PF18152.1 OAP54318.1 - 0.033 14.0 1.3 0.075 12.9 1.3 1.6 1 0 0 1 1 1 0 DAHP synthase ferredoxin-like domain Formyl_trans_N PF00551.19 OAP54319.1 - 1.8e-19 70.2 0.0 2.7e-19 69.6 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase Zn_clus PF00172.18 OAP54320.1 - 9.5e-07 28.8 10.5 9.5e-07 28.8 10.5 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 OAP54320.1 - 0.034 13.0 1.9 0.069 11.9 1.9 1.5 1 1 0 1 1 1 0 Fungal specific transcription factor domain Beta-lactamase PF00144.24 OAP54321.1 - 8.5e-29 100.8 0.7 4.5e-28 98.5 0.7 1.9 1 1 0 1 1 1 1 Beta-lactamase Pex19 PF04614.12 OAP54322.1 - 7.9e-60 202.7 12.6 7.9e-60 202.7 12.6 2.5 2 1 0 2 2 2 1 Pex19 protein family Neuromodulin_N PF10580.9 OAP54322.1 - 0.066 13.0 0.1 0.15 11.9 0.1 1.6 1 0 0 1 1 1 0 Gap junction protein N-terminal region PNISR PF15996.5 OAP54322.1 - 0.6 10.4 18.3 0.26 11.6 13.7 2.0 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR Pkinase_fungal PF17667.1 OAP54322.1 - 1.3 7.7 5.6 1.9 7.1 5.6 1.2 1 0 0 1 1 1 0 Fungal protein kinase CNDH2_C PF16858.5 OAP54322.1 - 2.2 8.1 9.7 3.9 7.3 9.7 1.5 1 1 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term MscS_TM PF12794.7 OAP54323.1 - 2.7 6.8 3.6 4.2 6.2 3.6 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Apt1 PF10351.9 OAP54324.1 - 0.28 10.0 6.4 0.29 9.9 6.4 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SPX PF03105.19 OAP54324.1 - 0.51 10.2 9.0 0.56 10.1 9.0 1.2 1 0 0 1 1 1 0 SPX domain PQ-loop PF04193.14 OAP54325.1 - 1.1e-36 124.4 10.7 1.1e-18 66.8 2.6 2.8 3 0 0 3 3 3 2 PQ loop repeat Transformer PF06495.11 OAP54325.1 - 0.033 14.3 5.8 0.051 13.7 5.8 1.2 1 0 0 1 1 1 0 Fruit fly transformer protein ER_lumen_recept PF00810.18 OAP54325.1 - 0.06 14.2 0.1 1.6 9.5 0.0 2.2 2 0 0 2 2 2 0 ER lumen protein retaining receptor Fungal_trans PF04082.18 OAP54326.1 - 6.2e-13 48.4 0.4 9.6e-13 47.8 0.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans_2 PF11951.8 OAP54326.1 - 0.1 11.4 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain Fungal_trans PF04082.18 OAP54327.1 - 1.4e-21 76.7 0.1 2.6e-21 75.9 0.1 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP54327.1 - 7.8e-09 35.5 10.1 1.5e-08 34.6 10.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BPL_LplA_LipB PF03099.19 OAP54328.1 - 2.2e-08 34.1 0.0 4e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family MR_MLE_C PF13378.6 OAP54329.1 - 4.2e-54 183.4 0.0 5.7e-54 183.0 0.0 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 OAP54329.1 - 1e-19 70.8 0.0 3e-19 69.4 0.0 1.7 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain adh_short_C2 PF13561.6 OAP54330.1 - 9.4e-51 172.6 0.9 1.2e-50 172.3 0.9 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP54330.1 - 9.4e-50 168.8 1.2 1.2e-49 168.5 1.2 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAP54330.1 - 3.2e-09 36.9 0.9 4.8e-09 36.4 0.9 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAP54330.1 - 0.0037 16.7 0.3 0.0087 15.5 0.1 1.8 3 0 0 3 3 3 1 NAD dependent epimerase/dehydratase family Flavodoxin_1 PF00258.25 OAP54330.1 - 0.082 13.1 0.1 13 6.0 0.0 2.4 3 0 0 3 3 3 0 Flavodoxin UDPG_MGDP_dh_C PF03720.15 OAP54330.1 - 0.14 12.6 0.0 0.31 11.5 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Sugar_tr PF00083.24 OAP54331.1 - 4.9e-76 256.4 21.8 6e-76 256.1 21.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP54331.1 - 2.7e-19 69.3 25.1 2.7e-19 69.3 25.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3493 PF11998.8 OAP54331.1 - 2.9 8.1 15.7 6.9 6.9 0.3 4.8 4 0 0 4 4 4 0 Low psii accumulation1 / Rep27 adh_short_C2 PF13561.6 OAP54332.1 - 1.6e-56 191.5 0.6 1.9e-56 191.3 0.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP54332.1 - 1e-46 158.9 1.3 1.3e-46 158.6 1.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAP54332.1 - 2.3e-10 40.7 0.2 3e-10 40.3 0.2 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAP54332.1 - 0.028 13.9 0.1 0.037 13.5 0.1 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Fungal_trans PF04082.18 OAP54333.1 - 2.9e-25 88.8 0.0 4.8e-25 88.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain FMO-like PF00743.19 OAP54334.1 - 7.6e-20 70.8 0.5 8e-17 60.8 0.1 2.6 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 OAP54334.1 - 3.4e-11 42.9 0.0 3.5e-08 33.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAP54334.1 - 3.9e-07 30.2 2.2 4.5e-07 30.0 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 OAP54334.1 - 2.2e-06 27.1 0.0 0.00039 19.8 0.0 3.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAP54334.1 - 3.5e-06 26.4 0.0 0.0003 20.0 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 OAP54334.1 - 0.00043 20.3 0.1 0.077 13.0 0.0 2.9 3 0 0 3 3 3 1 FAD-NAD(P)-binding PRMT5 PF05185.16 OAP54334.1 - 0.024 14.5 0.2 1.1 9.1 0.2 2.5 2 0 0 2 2 2 0 PRMT5 arginine-N-methyltransferase Thi4 PF01946.17 OAP54334.1 - 0.21 10.8 0.2 9 5.5 0.0 2.5 2 0 0 2 2 2 0 Thi4 family HI0933_like PF03486.14 OAP54334.1 - 0.26 10.0 0.1 4.7 5.8 0.3 2.1 2 0 0 2 2 2 0 HI0933-like protein adh_short_C2 PF13561.6 OAP54335.1 - 4.4e-45 154.1 0.1 7.5e-44 150.0 0.1 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP54335.1 - 4e-36 124.3 0.1 1.2e-35 122.8 0.1 1.7 1 1 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 OAP54335.1 - 1.4e-08 34.6 0.0 2.2e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 OAP54335.1 - 1.6e-06 28.2 1.2 0.00018 21.5 1.2 2.7 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 OAP54335.1 - 1.7e-06 27.2 0.1 2.2e-06 26.9 0.1 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family AlaDh_PNT_C PF01262.21 OAP54335.1 - 0.013 14.8 1.4 0.17 11.1 0.0 2.1 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain adh_short PF00106.25 OAP54336.1 - 1.3e-34 119.4 0.2 1.8e-34 118.9 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP54336.1 - 2.6e-28 99.2 0.0 3.4e-28 98.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP54336.1 - 1.7e-05 24.8 0.1 2.5e-05 24.3 0.1 1.2 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 OAP54336.1 - 0.0015 18.8 0.0 0.0048 17.2 0.1 1.7 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain ClpS PF02617.17 OAP54336.1 - 0.0045 16.7 0.0 0.48 10.2 0.0 2.4 2 0 0 2 2 2 1 ATP-dependent Clp protease adaptor protein ClpS NmrA PF05368.13 OAP54336.1 - 0.0055 16.3 0.6 0.012 15.2 0.4 1.6 2 0 0 2 2 2 1 NmrA-like family Shikimate_DH PF01488.20 OAP54336.1 - 0.022 14.8 0.0 0.034 14.2 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Sugar_tr PF00083.24 OAP54337.1 - 1.6e-78 264.6 20.1 1.9e-78 264.4 20.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP54337.1 - 1.3e-21 77.0 36.3 4.8e-18 65.2 16.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans_2 PF11951.8 OAP54338.1 - 0.00082 18.3 0.0 0.0015 17.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pkinase PF00069.25 OAP54339.1 - 7.4e-49 166.5 0.0 2.2e-32 112.5 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAP54339.1 - 2.8e-20 72.7 0.0 8.4e-19 67.9 0.0 2.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAP54339.1 - 7.8e-08 32.0 0.0 4.1e-05 23.0 0.0 2.3 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 OAP54339.1 - 0.00036 20.5 0.0 0.002 18.1 0.0 2.3 3 0 0 3 3 3 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OAP54339.1 - 0.0012 17.7 0.0 0.0049 15.7 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase Alg14 PF08660.11 OAP54341.1 - 1.3e-49 168.5 0.0 2.4e-49 167.6 0.0 1.4 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like Ima1_N PF09779.9 OAP54342.1 - 1.1e-33 117.0 5.1 1.9e-33 116.2 5.1 1.4 1 0 0 1 1 1 1 Ima1 N-terminal domain OrfB_Zn_ribbon PF07282.11 OAP54342.1 - 0.028 14.3 0.6 0.089 12.7 0.6 1.9 1 0 0 1 1 1 0 Putative transposase DNA-binding domain DUF3382 PF11862.8 OAP54342.1 - 0.092 13.0 1.3 7.1 7.0 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3382) PriA_CRR PF18319.1 OAP54342.1 - 1.6 8.8 6.5 0.25 11.4 1.6 2.1 2 0 0 2 2 2 0 PriA DNA helicase Cys-rich region (CRR) domain EMP24_GP25L PF01105.24 OAP54343.1 - 6e-49 166.4 0.0 6.9e-49 166.3 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD SANT_DAMP1_like PF16282.5 OAP54344.1 - 6.1e-29 100.0 0.2 1.1e-28 99.2 0.2 1.5 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 DMAP1 PF05499.12 OAP54344.1 - 0.00011 22.2 0.2 0.00011 22.2 0.2 2.6 2 0 0 2 2 2 1 DNA methyltransferase 1-associated protein 1 (DMAP1) Filo_VP35 PF02097.15 OAP54345.1 - 0.021 13.9 0.4 0.048 12.7 0.0 1.7 2 0 0 2 2 2 0 Filoviridae VP35 LCD1 PF09798.9 OAP54345.1 - 0.029 12.9 5.9 0.051 12.1 5.9 1.3 1 0 0 1 1 1 0 DNA damage checkpoint protein Cep57_CLD_2 PF14197.6 OAP54345.1 - 0.078 13.1 2.1 0.27 11.3 0.9 2.3 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 Tup_N PF08581.10 OAP54345.1 - 1.1 9.6 7.9 38 4.7 0.0 2.6 2 0 0 2 2 2 0 Tup N-terminal DUF3294 PF07957.11 OAP54346.1 - 0.022 14.5 0.1 0.031 14.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3294) Abhydrolase_8 PF06259.12 OAP54346.1 - 0.083 12.5 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase LPP20 PF02169.16 OAP54346.1 - 0.091 13.1 2.5 0.13 12.6 2.5 1.2 1 0 0 1 1 1 0 LPP20 lipoprotein WD40 PF00400.32 OAP54347.1 - 3.5e-36 122.6 17.1 9.4e-10 38.9 0.1 8.3 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAP54347.1 - 4.4e-10 39.7 1.2 0.062 13.6 0.0 5.4 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OAP54347.1 - 5.7e-09 35.2 2.5 0.0048 15.6 0.0 4.7 4 1 1 5 5 5 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 OAP54347.1 - 7.4e-07 28.4 0.0 1.3 7.9 0.0 4.4 2 1 2 4 4 4 4 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 OAP54347.1 - 8.7e-05 21.4 0.0 0.39 9.4 0.0 3.3 1 1 1 3 3 3 2 Nup133 N terminal like PALB2_WD40 PF16756.5 OAP54347.1 - 0.00016 20.7 2.5 0.0002 20.4 0.1 2.4 4 0 0 4 4 4 1 Partner and localizer of BRCA2 WD40 domain Frtz PF11768.8 OAP54347.1 - 0.0099 14.2 0.0 0.015 13.7 0.0 1.2 1 0 0 1 1 1 1 WD repeat-containing and planar cell polarity effector protein Fritz Hira PF07569.11 OAP54347.1 - 0.026 14.2 2.4 3.1 7.4 0.2 3.8 3 1 1 4 4 4 0 TUP1-like enhancer of split DUF202 PF02656.15 OAP54348.1 - 2.2e-13 50.4 4.6 2.2e-13 50.4 4.6 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF5337 PF17272.2 OAP54348.1 - 1.9 8.4 11.4 0.18 11.7 5.6 2.3 2 1 0 2 2 2 0 Family of unknown function (DUF5337) Tctex-1 PF03645.13 OAP54349.1 - 1.3e-32 112.1 0.0 2.7e-32 111.1 0.0 1.6 1 0 0 1 1 1 1 Tctex-1 family DUF3425 PF11905.8 OAP54350.1 - 7.2e-12 45.4 0.1 1.2e-11 44.6 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 OAP54350.1 - 0.0014 18.7 17.4 0.011 15.9 17.4 2.0 1 1 0 1 1 1 1 bZIP transcription factor PikAIV_N PF18605.1 OAP54350.1 - 0.035 13.7 5.4 0.044 13.4 3.5 2.1 1 1 1 2 2 2 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain Seadorna_VP6 PF07407.11 OAP54350.1 - 0.084 11.8 0.4 0.12 11.3 0.4 1.1 1 0 0 1 1 1 0 Seadornavirus VP6 protein bZIP_Maf PF03131.17 OAP54350.1 - 0.2 12.2 9.8 0.43 11.1 9.8 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor PRKG1_interact PF15898.5 OAP54350.1 - 0.47 11.4 9.1 0.77 10.7 9.1 1.3 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain LAMTOR PF15454.6 OAP54350.1 - 1.3 9.7 9.3 1.4 9.6 1.1 2.9 1 1 2 3 3 3 0 Late endosomal/lysosomal adaptor and MAPK and MTOR activator bZIP_2 PF07716.15 OAP54350.1 - 6.7 6.9 20.6 3.8e+02 1.3 20.6 2.2 1 1 0 1 1 1 0 Basic region leucine zipper G-alpha PF00503.20 OAP54351.1 - 4.6e-96 322.1 0.0 6e-96 321.7 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 OAP54351.1 - 1.3e-12 47.5 0.8 1.3e-06 28.0 0.1 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 OAP54351.1 - 0.0083 16.3 0.9 1.6 9.0 0.2 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 OAP54351.1 - 0.015 15.4 0.2 4.4 7.4 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase PhoPQ_related PF10142.9 OAP54351.1 - 0.098 11.3 0.0 0.14 10.7 0.0 1.1 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein AAA_29 PF13555.6 OAP54351.1 - 0.21 11.4 0.2 0.82 9.5 0.3 1.9 1 1 1 2 2 2 0 P-loop containing region of AAA domain Zn_clus PF00172.18 OAP54352.1 - 3.1e-08 33.6 7.7 3.1e-08 33.6 7.7 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DAO PF01266.24 OAP54353.1 - 7.1e-42 144.2 0.5 9.9e-42 143.8 0.5 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Rieske PF00355.26 OAP54353.1 - 1.3e-09 37.9 2.0 6.8e-09 35.6 0.0 2.6 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain NAD_binding_8 PF13450.6 OAP54353.1 - 1e-06 28.9 0.3 2.5e-06 27.6 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 OAP54353.1 - 2.9e-06 26.8 0.4 4.8e-06 26.1 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 OAP54353.1 - 7.2e-06 25.4 0.0 1.3e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 OAP54353.1 - 3.5e-05 23.3 0.9 0.00058 19.3 0.3 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 OAP54353.1 - 0.00024 20.4 0.0 0.00052 19.3 0.0 1.5 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 OAP54353.1 - 0.0015 17.7 0.4 0.0024 17.0 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 OAP54353.1 - 0.0039 16.3 0.1 0.0067 15.5 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Amino_oxidase PF01593.24 OAP54353.1 - 0.0074 15.6 1.4 0.03 13.6 0.1 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase GIDA PF01134.22 OAP54353.1 - 0.011 14.8 0.1 0.022 13.9 0.1 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A HI0933_like PF03486.14 OAP54353.1 - 0.048 12.4 0.2 0.069 11.8 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein AlaDh_PNT_C PF01262.21 OAP54353.1 - 0.075 12.3 0.2 0.33 10.2 0.1 1.9 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 OAP54353.1 - 0.099 12.5 0.1 0.2 11.5 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.27 OAP54353.1 - 0.11 13.1 0.2 0.25 11.9 0.2 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAP54353.1 - 0.17 11.1 0.0 0.3 10.3 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAP54353.1 - 0.21 11.6 0.8 0.52 10.3 0.2 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding NUDIX PF00293.28 OAP54354.1 - 5.3e-16 58.8 0.1 1.1e-15 57.8 0.1 1.5 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.11 OAP54354.1 - 1.3e-08 35.4 0.0 4.6e-08 33.6 0.0 1.9 2 0 0 2 2 2 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.11 OAP54354.1 - 2.8e-06 26.9 1.9 4.9e-06 26.1 1.9 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain Auto_anti-p27 PF06677.12 OAP54354.1 - 0.15 12.2 0.7 0.27 11.4 0.7 1.4 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Fungal_trans PF04082.18 OAP54355.1 - 1.6e-23 83.1 0.0 3.5e-23 82.0 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP54355.1 - 0.00046 20.2 8.2 0.00046 20.2 8.2 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 2-Hacid_dh_C PF02826.19 OAP54356.1 - 3.6e-50 169.8 0.0 5e-50 169.3 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 OAP54356.1 - 1e-16 60.8 0.0 1.5e-16 60.2 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 OAP54356.1 - 3.2e-06 27.4 0.0 2.1e-05 24.8 0.0 2.2 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase PROCN PF08083.11 OAP54356.1 - 0.14 10.9 0.0 0.19 10.4 0.0 1.1 1 0 0 1 1 1 0 PROCN (NUC071) domain AAA_16 PF13191.6 OAP54357.1 - 4.5e-06 27.1 0.0 5.8e-05 23.5 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 OAP54357.1 - 5.9e-05 23.0 0.0 0.00048 20.1 0.0 2.5 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 OAP54357.1 - 0.0005 20.3 0.0 0.019 15.2 0.0 3.0 2 1 0 2 2 2 1 AAA domain SesA PF17107.5 OAP54357.1 - 0.0022 18.2 1.1 0.014 15.6 0.0 2.4 2 0 0 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases AAA_18 PF13238.6 OAP54357.1 - 0.019 15.5 0.0 0.054 14.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 OAP54357.1 - 0.022 14.5 0.3 0.097 12.4 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain Ank_4 PF13637.6 OAP54357.1 - 0.028 15.0 0.0 26 5.5 0.0 4.1 4 0 0 4 4 4 0 Ankyrin repeats (many copies) AAA_30 PF13604.6 OAP54357.1 - 0.034 13.9 0.0 0.13 12.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain FA_FANCE PF11510.8 OAP54357.1 - 0.039 13.3 0.1 0.28 10.5 0.1 2.0 1 1 0 2 2 2 0 Fanconi Anaemia group E protein FANCE KAP_NTPase PF07693.14 OAP54357.1 - 0.058 12.6 0.3 1.7 7.8 0.0 2.3 1 1 0 2 2 2 0 KAP family P-loop domain RNA_helicase PF00910.22 OAP54357.1 - 0.071 13.5 0.0 0.15 12.5 0.0 1.5 1 0 0 1 1 1 0 RNA helicase DUF3549 PF12069.8 OAP54357.1 - 0.08 12.0 0.6 0.14 11.2 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3549) AAA_24 PF13479.6 OAP54357.1 - 0.08 12.7 0.0 1.9 8.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 OAP54357.1 - 0.11 13.0 0.0 0.43 11.1 0.0 2.0 2 0 0 2 2 2 0 ABC transporter Ploopntkinase3 PF18751.1 OAP54357.1 - 0.14 12.1 0.0 0.34 10.8 0.0 1.6 1 1 0 1 1 1 0 P-loop Nucleotide Kinase3 zf-C2H2 PF00096.26 OAP54358.1 - 7.3e-09 35.6 12.0 0.0011 19.3 0.3 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAP54358.1 - 6.9e-08 32.7 9.4 0.028 15.2 0.9 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OAP54358.1 - 0.0042 17.5 0.2 0.0042 17.5 0.2 3.3 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_8 PF15909.5 OAP54358.1 - 0.06 13.6 2.1 6.6 7.1 0.2 2.7 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-met PF12874.7 OAP54358.1 - 0.52 10.8 2.1 0.97 9.9 0.8 2.2 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-Di19 PF05605.12 OAP54358.1 - 4.4 7.7 5.7 11 6.5 5.4 1.9 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Methyltransf_33 PF10017.9 OAP54359.1 - 5.7e-83 278.6 0.0 6.7e-83 278.4 0.0 1.0 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent Sugar_tr PF00083.24 OAP54360.1 - 2.4e-89 300.3 24.8 3e-89 300.0 24.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP54360.1 - 2.4e-16 59.6 27.9 2.4e-16 59.6 27.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.25 OAP54361.1 - 1.7e-29 103.0 0.0 7.3e-29 100.9 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP54361.1 - 3e-11 43.1 0.1 4.7e-10 39.2 0.1 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAP54361.1 - 0.00029 19.7 0.0 0.00039 19.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OAP54361.1 - 0.3 11.0 1.4 2.3 8.1 0.1 2.3 2 1 0 2 2 2 0 Phosphotransferase enzyme family HET PF06985.11 OAP54362.1 - 2.8e-12 47.2 4.6 3.1e-10 40.6 0.4 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) AAA_2 PF07724.14 OAP54364.1 - 3e-47 160.9 0.1 1.4e-45 155.5 0.0 3.1 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 OAP54364.1 - 7.1e-36 122.3 2.0 7.1e-36 122.3 2.0 2.6 1 1 1 2 2 2 1 AAA lid domain ClpB_D2-small PF10431.9 OAP54364.1 - 7.7e-27 93.2 0.2 2.8e-26 91.4 0.2 2.1 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 OAP54364.1 - 1.4e-20 74.1 0.1 4e-10 40.2 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 OAP54364.1 - 2.2e-13 50.4 3.3 1.9e-08 34.4 0.0 3.8 4 0 0 4 4 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OAP54364.1 - 1.1e-08 35.7 9.2 0.00049 20.5 0.5 4.2 3 2 1 4 4 3 2 AAA ATPase domain Sigma54_activat PF00158.26 OAP54364.1 - 1.6e-08 34.4 0.9 5.1e-05 23.0 0.1 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_22 PF13401.6 OAP54364.1 - 4.8e-07 30.1 3.2 0.033 14.4 0.0 3.7 3 2 0 3 3 2 2 AAA domain AAA_14 PF13173.6 OAP54364.1 - 2.9e-06 27.3 0.5 0.095 12.7 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_7 PF12775.7 OAP54364.1 - 1.4e-05 24.7 0.0 0.054 13.0 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region TniB PF05621.11 OAP54364.1 - 1.8e-05 24.2 0.0 0.041 13.3 0.0 4.2 4 1 0 4 4 3 1 Bacterial TniB protein NACHT PF05729.12 OAP54364.1 - 2.3e-05 24.4 0.1 0.13 12.2 0.0 2.6 2 0 0 2 2 2 2 NACHT domain IstB_IS21 PF01695.17 OAP54364.1 - 2.9e-05 23.9 0.1 0.096 12.4 0.1 2.8 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_28 PF13521.6 OAP54364.1 - 0.00017 21.9 2.6 0.046 14.0 0.0 3.9 3 1 1 4 4 4 1 AAA domain AAA_18 PF13238.6 OAP54364.1 - 0.00017 22.1 1.1 0.42 11.2 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_23 PF13476.6 OAP54364.1 - 0.00019 22.0 7.5 1.3 9.5 5.7 3.5 3 0 0 3 3 3 1 AAA domain ATPase_2 PF01637.18 OAP54364.1 - 0.00022 21.2 8.7 0.51 10.2 0.0 4.4 3 2 1 4 4 3 1 ATPase domain predominantly from Archaea AAA_24 PF13479.6 OAP54364.1 - 0.00046 20.0 0.0 0.3 10.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 OAP54364.1 - 0.00077 20.0 0.8 0.47 11.0 0.0 3.3 3 0 0 3 3 3 1 ABC transporter Mg_chelatase PF01078.21 OAP54364.1 - 0.0012 18.3 0.4 3.5 6.9 0.0 3.7 3 1 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_30 PF13604.6 OAP54364.1 - 0.0012 18.6 1.8 0.14 11.9 0.0 3.6 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 OAP54364.1 - 0.0015 18.9 0.0 0.71 10.3 0.0 2.7 2 0 0 2 2 2 1 RNA helicase ResIII PF04851.15 OAP54364.1 - 0.002 18.2 0.5 2.8 7.9 0.0 3.4 4 0 0 4 4 3 1 Type III restriction enzyme, res subunit Roc PF08477.13 OAP54364.1 - 0.002 18.3 0.5 0.55 10.5 0.0 2.8 3 0 0 3 3 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_19 PF13245.6 OAP54364.1 - 0.0027 18.0 1.2 0.24 11.7 0.2 3.3 2 2 0 2 2 2 1 AAA domain TsaE PF02367.17 OAP54364.1 - 0.0035 17.3 0.0 2.4 8.2 0.0 2.6 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RsgA_GTPase PF03193.16 OAP54364.1 - 0.0057 16.6 0.0 2 8.3 0.0 2.8 2 0 0 2 2 2 1 RsgA GTPase SRP54 PF00448.22 OAP54364.1 - 0.0074 15.9 0.0 1 8.9 0.0 2.5 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain PduV-EutP PF10662.9 OAP54364.1 - 0.012 15.3 0.2 0.7 9.6 0.0 2.7 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation DUF815 PF05673.13 OAP54364.1 - 0.013 14.7 0.2 0.77 8.9 0.2 3.2 3 2 0 3 3 3 0 Protein of unknown function (DUF815) Zeta_toxin PF06414.12 OAP54364.1 - 0.014 14.7 0.0 1.3 8.2 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin AAA_33 PF13671.6 OAP54364.1 - 0.026 14.7 1.4 6 7.0 0.0 3.0 3 0 0 3 3 2 0 AAA domain AAA_6 PF12774.7 OAP54364.1 - 0.036 13.0 0.0 4.3 6.2 0.0 2.9 3 0 0 3 3 3 0 Hydrolytic ATP binding site of dynein motor region RuvB_N PF05496.12 OAP54364.1 - 0.044 13.5 0.1 2.2 8.0 0.0 3.2 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 OAP54364.1 - 0.045 13.3 0.1 2.4 7.7 0.1 3.0 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.6 OAP54364.1 - 0.054 13.2 0.0 7.2 6.4 0.0 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain NTPase_1 PF03266.15 OAP54364.1 - 0.06 13.2 0.1 1 9.3 0.0 2.7 2 0 0 2 2 2 0 NTPase NB-ARC PF00931.22 OAP54364.1 - 0.076 12.2 2.2 6.8 5.8 0.0 3.4 3 0 0 3 3 3 0 NB-ARC domain ATP_bind_1 PF03029.17 OAP54364.1 - 0.079 12.7 0.0 1.3 8.7 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DUF99 PF01949.16 OAP54364.1 - 0.083 12.3 1.4 1.3 8.4 0.0 2.7 3 0 0 3 3 2 0 Protein of unknown function DUF99 Torsin PF06309.11 OAP54364.1 - 0.083 13.0 0.0 1 9.5 0.0 2.5 3 0 0 3 3 2 0 Torsin Viral_helicase1 PF01443.18 OAP54364.1 - 0.1 12.3 0.1 19 4.9 0.0 2.7 2 1 0 2 2 2 0 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.21 OAP54364.1 - 0.14 11.6 3.9 0.58 9.6 0.1 2.3 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain LMBR1 PF04791.16 OAP54364.1 - 0.18 10.7 1.8 0.38 9.6 1.3 1.6 2 0 0 2 2 2 0 LMBR1-like membrane protein GrpE PF01025.19 OAP54364.1 - 0.28 10.9 10.5 0.76 9.4 10.5 1.8 1 0 0 1 1 1 0 GrpE GAS PF13851.6 OAP54364.1 - 0.28 10.5 13.3 0.59 9.5 13.3 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding ERM PF00769.19 OAP54364.1 - 0.39 10.5 15.8 0.61 9.9 15.8 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family AAA_21 PF13304.6 OAP54364.1 - 0.62 9.8 4.0 0.83 9.4 0.0 3.0 3 1 1 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system Rootletin PF15035.6 OAP54364.1 - 0.81 9.7 12.3 0.42 10.6 9.9 1.7 2 0 0 2 2 1 0 Ciliary rootlet component, centrosome cohesion DivIC PF04977.15 OAP54364.1 - 0.83 9.5 16.6 1.5 8.6 9.3 2.8 1 1 1 2 2 2 0 Septum formation initiator Atg14 PF10186.9 OAP54364.1 - 7.5 5.5 9.3 12 4.8 9.3 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4094 PF13334.6 OAP54364.1 - 7.6 7.0 8.0 0.51 10.8 0.6 2.9 3 0 0 3 3 1 0 Domain of unknown function (DUF4094) BTB PF00651.31 OAP54365.1 - 1.3e-07 31.8 0.0 1.9e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain SOG2 PF10428.9 OAP54366.1 - 0.059 12.6 10.6 0.07 12.3 10.6 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein Macoilin PF09726.9 OAP54366.1 - 1.1 7.7 10.0 1.4 7.4 10.0 1.0 1 0 0 1 1 1 0 Macoilin family EF1_GNE PF00736.19 OAP54367.1 - 2.2e-31 107.9 5.1 4.2e-31 107.0 5.1 1.5 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 OAP54367.1 - 4.4e-12 46.2 4.8 4.4e-12 46.2 4.8 2.9 3 0 0 3 3 3 1 Eukaryotic elongation factor 1 beta central acidic region GST_C PF00043.25 OAP54367.1 - 0.081 13.2 0.7 0.41 10.9 0.0 2.4 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain DUF211 PF02680.14 OAP54367.1 - 0.14 12.3 1.8 0.23 11.7 1.8 1.5 1 1 0 1 1 1 0 Uncharacterized ArCR, COG1888 DHO_dh PF01180.21 OAP54368.1 - 1.1e-16 60.9 0.0 1.5e-16 60.5 0.0 1.2 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase NMO PF03060.15 OAP54368.1 - 0.26 10.6 1.6 0.42 10.0 1.6 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase RNB PF00773.19 OAP54369.1 - 1.2e-82 277.9 0.0 2.5e-82 276.8 0.0 1.6 1 0 0 1 1 1 1 RNB domain Dis3l2_C_term PF17877.1 OAP54369.1 - 3.8e-26 91.2 0.0 1.4e-25 89.4 0.0 2.0 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal OB_Dis3 PF17849.1 OAP54369.1 - 1.6e-25 88.9 0.0 3.9e-25 87.7 0.0 1.7 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) CSD2 PF17876.1 OAP54369.1 - 8.9e-05 22.6 0.0 0.041 14.1 0.0 2.7 2 0 0 2 2 2 2 Cold shock domain Rrp44_CSD1 PF17216.3 OAP54369.1 - 0.00029 20.6 0.0 0.00058 19.6 0.0 1.4 1 0 0 1 1 1 1 Rrp44-like cold shock domain Rrp44_S1 PF17215.3 OAP54369.1 - 0.061 13.3 0.0 0.17 11.9 0.0 1.7 1 0 0 1 1 1 0 S1 domain GLE1 PF07817.13 OAP54370.1 - 6.9e-39 133.5 0.0 1.3e-38 132.7 0.0 1.4 1 0 0 1 1 1 1 GLE1-like protein Abhydrolase_1 PF00561.20 OAP54371.1 - 6.1e-21 75.2 0.0 3.5e-20 72.8 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAP54371.1 - 2.2e-15 57.9 2.4 1.3e-14 55.3 2.4 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAP54371.1 - 1.9e-07 30.6 0.0 2e-06 27.3 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 OAP54371.1 - 0.061 12.2 0.0 0.11 11.4 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase enzyme DUF3530 PF12048.8 OAP54371.1 - 0.15 11.5 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) DUF543 PF04418.12 OAP54371.1 - 0.19 11.8 0.1 0.44 10.6 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF543) COesterase PF00135.28 OAP54372.1 - 3.8e-70 237.2 0.0 5.4e-70 236.7 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAP54372.1 - 1e-10 41.9 0.0 4.6e-06 26.6 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAP54372.1 - 0.019 14.3 0.0 0.029 13.6 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Say1_Mug180 PF10340.9 OAP54372.1 - 0.087 11.7 0.0 5.2 5.8 0.0 2.1 2 0 0 2 2 2 0 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 OAP54372.1 - 0.093 12.2 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF2914 PF11141.8 OAP54372.1 - 1.9 8.3 7.5 8.7 6.2 0.1 3.3 3 1 1 4 4 4 0 Protein of unknown function (DUF2914) Rsm22 PF09243.10 OAP54374.1 - 8.2e-29 100.7 0.0 1.6e-13 50.5 0.0 3.8 3 1 0 3 3 3 2 Mitochondrial small ribosomal subunit Rsm22 CEP19 PF14933.6 OAP54374.1 - 0.039 14.3 2.5 0.043 14.1 0.3 2.1 2 0 0 2 2 2 0 CEP19-like protein DUF3275 PF11679.8 OAP54374.1 - 0.058 13.4 0.9 7 6.6 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3275) NIPSNAP PF07978.13 OAP54375.1 - 1.1e-34 118.7 0.1 1.4e-27 95.9 0.0 2.3 2 0 0 2 2 2 2 NIPSNAP Putative_PNPOx PF01243.20 OAP54376.1 - 5.8e-10 39.2 0.0 1.3e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyrid_oxidase_2 PF13883.6 OAP54376.1 - 7.5e-05 22.8 0.3 0.00011 22.2 0.3 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxase_2 PF12766.7 OAP54376.1 - 0.0038 17.8 0.0 0.0062 17.1 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Ras PF00071.22 OAP54377.1 - 3.5e-54 182.8 0.0 4.1e-54 182.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAP54377.1 - 2.2e-21 76.3 0.0 3.4e-21 75.7 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAP54377.1 - 1.1e-07 31.5 0.0 1.7e-07 30.8 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OAP54377.1 - 0.0065 15.8 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 OAP54377.1 - 0.021 14.0 0.0 0.061 12.5 0.0 1.4 1 1 0 1 1 1 0 G-protein alpha subunit MMR_HSR1 PF01926.23 OAP54377.1 - 0.051 13.6 0.0 0.083 13.0 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase SRPRB PF09439.10 OAP54377.1 - 0.069 12.6 0.0 0.09 12.2 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 OAP54377.1 - 0.092 12.7 0.0 10 6.0 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase CttA_N PF18244.1 OAP54379.1 - 0.17 12.3 0.1 0.34 11.4 0.1 1.4 1 0 0 1 1 1 0 Cellulose-binding protein CttA N-terminal domain FAD_binding_3 PF01494.19 OAP54380.1 - 4.4e-23 82.1 0.4 3e-22 79.3 0.4 2.0 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 OAP54380.1 - 2.4e-08 33.5 0.1 4e-08 32.7 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 OAP54380.1 - 2.1e-07 30.5 0.4 0.00051 19.4 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAP54380.1 - 2.7e-05 24.3 1.3 6.1e-05 23.2 1.3 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 OAP54380.1 - 0.0004 19.4 0.7 0.06 12.2 0.3 2.1 2 0 0 2 2 2 2 Tryptophan halogenase DAO PF01266.24 OAP54380.1 - 0.00078 19.1 9.0 0.03 13.9 6.9 2.3 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 OAP54380.1 - 0.002 18.6 0.4 0.0053 17.3 0.2 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAP54380.1 - 0.0039 16.5 3.1 0.058 12.6 0.9 2.2 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 OAP54380.1 - 0.0043 16.2 0.7 0.0068 15.5 0.7 1.3 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.24 OAP54380.1 - 0.024 13.9 1.7 0.87 8.8 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase GIDA PF01134.22 OAP54380.1 - 0.046 12.8 0.1 0.061 12.4 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Rossmann-like PF10727.9 OAP54380.1 - 0.081 12.8 1.3 0.16 11.8 0.8 1.7 2 0 0 2 2 1 0 Rossmann-like domain ApbA PF02558.16 OAP54380.1 - 0.11 12.1 0.9 0.2 11.3 0.9 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.6 OAP54380.1 - 0.15 11.3 0.6 0.26 10.5 0.3 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 OAP54380.1 - 0.2 11.5 0.6 0.37 10.6 0.6 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 OAP54380.1 - 0.33 11.2 1.4 0.65 10.3 0.6 1.9 2 0 0 2 2 2 0 TrkA-N domain AlaDh_PNT_C PF01262.21 OAP54380.1 - 0.34 10.2 1.4 0.69 9.2 1.4 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 OAP54380.1 - 0.37 9.4 4.8 0.21 10.2 2.6 1.6 2 0 0 2 2 2 0 HI0933-like protein Aldedh PF00171.22 OAP54381.1 - 3.4e-120 401.7 1.6 4e-120 401.4 1.6 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 OAP54381.1 - 0.0048 16.4 0.0 0.0098 15.4 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) ADH_N PF08240.12 OAP54382.1 - 1.3e-23 82.9 2.1 2.2e-23 82.2 2.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAP54382.1 - 3.7e-21 75.5 0.2 8.7e-21 74.3 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAP54382.1 - 5.5e-08 33.9 0.0 1.2e-07 32.8 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Fungal_trans PF04082.18 OAP54383.1 - 5.5e-32 110.9 0.8 8.1e-32 110.3 0.8 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP54383.1 - 3.7e-09 36.5 4.6 6.8e-09 35.7 4.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Rapsyn_N PF10579.9 OAP54383.1 - 0.073 13.2 0.1 0.18 11.9 0.1 1.6 1 0 0 1 1 1 0 Rapsyn N-terminal myristoylation and linker region Aldedh PF00171.22 OAP54384.1 - 2.9e-141 471.1 0.0 3.3e-141 471.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family p450 PF00067.22 OAP54385.1 - 6.2e-72 242.8 0.0 8e-72 242.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 OAP54386.1 - 3.6e-22 78.8 42.0 3.6e-22 78.8 42.0 1.9 1 1 0 2 2 2 1 Major Facilitator Superfamily Ntox27 PF15531.6 OAP54386.1 - 0.067 13.1 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial toxin 27 DUF3925 PF13063.6 OAP54386.1 - 0.3 11.3 4.6 16 5.8 0.1 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3925) Lactamase_B PF00753.27 OAP54387.1 - 2.8e-07 30.7 2.1 6.1e-07 29.6 2.1 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OAP54387.1 - 1.8e-05 24.3 0.0 5.2e-05 22.8 0.0 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain GST_C_6 PF17171.4 OAP54387.1 - 0.049 13.4 0.1 0.2 11.5 0.0 2.0 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Lactamase_B_3 PF13483.6 OAP54387.1 - 0.16 11.9 0.0 0.34 10.8 0.0 1.6 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Aldo_ket_red PF00248.21 OAP54388.1 - 1.6e-59 201.5 0.0 1.8e-59 201.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family FAA_hydrolase PF01557.18 OAP54389.1 - 1.7e-63 214.2 0.0 2.3e-63 213.8 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family GFA PF04828.14 OAP54390.1 - 8.8e-15 54.8 0.5 1.1e-14 54.5 0.5 1.1 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zinc_ribbon_11 PF11682.8 OAP54390.1 - 0.022 14.8 0.1 0.049 13.6 0.0 1.6 2 0 0 2 2 2 0 Probable zinc-ribbon Cupin_2 PF07883.11 OAP54391.1 - 1.1e-15 57.1 0.4 6.7e-12 45.0 0.1 2.5 2 0 0 2 2 2 2 Cupin domain Auxin_BP PF02041.16 OAP54391.1 - 0.043 13.5 0.0 8.7 6.0 0.0 2.2 2 0 0 2 2 2 0 Auxin binding protein Aldolase_II PF00596.21 OAP54392.1 - 2.3e-29 102.6 0.3 3.2e-29 102.2 0.3 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain adh_short PF00106.25 OAP54393.1 - 1.7e-23 83.1 0.0 2e-21 76.3 0.0 2.3 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAP54393.1 - 1.9e-14 53.8 0.0 1.2e-13 51.1 0.0 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP54393.1 - 3e-07 30.5 0.0 5.8e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.20 OAP54393.1 - 0.0034 17.5 0.1 0.021 14.9 0.0 2.1 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Ribosomal_L6 PF00347.23 OAP54394.1 - 1.6e-23 83.1 7.2 6.7e-12 45.9 0.2 2.2 2 0 0 2 2 2 2 Ribosomal protein L6 Hormone_2 PF00123.20 OAP54394.1 - 0.091 12.7 0.0 19 5.3 0.0 2.6 2 0 0 2 2 2 0 Peptide hormone IL34 PF15036.6 OAP54394.1 - 0.13 12.4 0.2 0.22 11.6 0.2 1.5 1 1 0 1 1 1 0 Interleukin 34 ATP_bind_1 PF03029.17 OAP54395.1 - 1e-74 251.3 0.0 2e-74 250.4 0.0 1.4 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein MeaB PF03308.16 OAP54395.1 - 9.3e-07 28.1 0.1 0.0015 17.6 0.0 2.4 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB GTP_EFTU PF00009.27 OAP54395.1 - 1.3e-06 28.0 0.0 6.5e-05 22.6 0.0 2.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain PRK PF00485.18 OAP54395.1 - 6.6e-05 22.7 1.1 0.028 14.2 0.0 2.5 3 0 0 3 3 2 1 Phosphoribulokinase / Uridine kinase family AAA_7 PF12775.7 OAP54395.1 - 0.0012 18.4 0.0 0.061 12.8 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_24 PF13479.6 OAP54395.1 - 0.0012 18.6 0.6 0.0024 17.6 0.0 1.9 2 0 0 2 2 1 1 AAA domain PduV-EutP PF10662.9 OAP54395.1 - 0.0012 18.6 0.0 0.012 15.4 0.0 2.5 3 0 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation SRP54 PF00448.22 OAP54395.1 - 0.0017 18.0 0.1 0.0085 15.7 0.0 2.1 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain MMR_HSR1 PF01926.23 OAP54395.1 - 0.0019 18.2 0.0 0.015 15.4 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase NACHT PF05729.12 OAP54395.1 - 0.0038 17.2 0.0 0.021 14.7 0.0 2.1 2 0 0 2 2 2 1 NACHT domain NB-ARC PF00931.22 OAP54395.1 - 0.0038 16.5 0.5 0.018 14.2 0.0 2.1 2 1 0 2 2 2 1 NB-ARC domain AAA_16 PF13191.6 OAP54395.1 - 0.0038 17.6 0.0 0.011 16.2 0.0 1.8 2 1 0 2 2 2 1 AAA ATPase domain CLP1_P PF16575.5 OAP54395.1 - 0.0039 17.0 0.0 0.022 14.6 0.0 2.1 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_22 PF13401.6 OAP54395.1 - 0.0044 17.3 0.0 0.017 15.4 0.0 2.0 1 0 0 1 1 1 1 AAA domain FeoB_N PF02421.18 OAP54395.1 - 0.0071 15.9 0.0 0.21 11.1 0.0 2.6 3 0 0 3 3 3 1 Ferrous iron transport protein B G-alpha PF00503.20 OAP54395.1 - 0.0081 15.4 0.1 0.46 9.6 0.0 2.6 3 0 0 3 3 3 1 G-protein alpha subunit Roc PF08477.13 OAP54395.1 - 0.011 16.0 0.0 1.5 9.1 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_33 PF13671.6 OAP54395.1 - 0.014 15.6 0.4 0.035 14.3 0.0 1.9 2 0 0 2 2 1 0 AAA domain ATPase_2 PF01637.18 OAP54395.1 - 0.014 15.3 0.7 0.12 12.3 0.0 2.3 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_30 PF13604.6 OAP54395.1 - 0.016 14.9 0.0 0.027 14.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 OAP54395.1 - 0.038 14.0 0.1 0.14 12.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 OAP54395.1 - 0.053 13.1 0.0 1.4 8.4 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Arf PF00025.21 OAP54395.1 - 0.062 12.7 0.0 9.3 5.7 0.0 2.9 2 1 0 2 2 2 0 ADP-ribosylation factor family Thymidylate_kin PF02223.17 OAP54395.1 - 0.093 12.4 0.6 0.71 9.5 0.0 2.3 2 0 0 2 2 2 0 Thymidylate kinase AAA_18 PF13238.6 OAP54395.1 - 0.11 13.0 2.6 1.2 9.6 0.0 2.9 3 0 0 3 3 2 0 AAA domain DUF87 PF01935.17 OAP54395.1 - 0.15 12.1 0.9 3.2 7.8 0.0 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain DUF1943 PF09172.11 OAP54395.1 - 0.21 10.8 3.1 0.36 10.0 3.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) SAPS PF04499.15 OAP54395.1 - 1.1 8.0 5.1 2.3 6.9 4.7 1.6 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein BUD22 PF09073.10 OAP54395.1 - 2.2 7.5 16.8 3.1 7.1 16.8 1.1 1 0 0 1 1 1 0 BUD22 DUF2151 PF10221.9 OAP54395.1 - 2.4 6.7 5.4 3.4 6.2 5.4 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator Aa_trans PF01490.18 OAP54396.1 - 2e-22 79.5 33.9 2.9e-22 78.9 33.9 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein CwfJ_C_2 PF04676.14 OAP54397.1 - 5e-31 107.5 0.1 5e-31 107.5 0.1 2.3 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 2 CwfJ_C_1 PF04677.15 OAP54397.1 - 2.5e-28 98.4 0.0 4.6e-28 97.5 0.0 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 FumaraseC_C PF10415.9 OAP54397.1 - 0.01 16.3 1.0 0.47 10.9 0.2 2.7 2 0 0 2 2 2 0 Fumarase C C-terminus DUF4404 PF14357.6 OAP54397.1 - 0.25 12.0 0.1 0.25 12.0 0.1 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) CAF20 PF17052.5 OAP54397.1 - 8.6 6.5 18.1 27 4.9 18.1 1.9 1 0 0 1 1 1 0 Cap associated factor 2-oxoacid_dh PF00198.23 OAP54398.1 - 1.2e-74 250.7 0.8 1.8e-74 250.1 0.8 1.3 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 OAP54398.1 - 9.9e-19 66.9 0.5 2.2e-18 65.8 0.5 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 OAP54398.1 - 5.6e-14 52.2 0.3 1.1e-13 51.2 0.3 1.5 1 0 0 1 1 1 1 e3 binding domain SspB PF04386.13 OAP54398.1 - 0.0061 16.5 0.5 0.012 15.5 0.5 1.4 1 0 0 1 1 1 1 Stringent starvation protein B PI-PLC-X PF00388.19 OAP54399.1 - 2.9e-09 36.7 0.0 4.2e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain SLAC1 PF03595.17 OAP54400.1 - 2.1e-73 247.4 48.5 2.6e-73 247.1 48.5 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Rrn6 PF10214.9 OAP54402.1 - 6.3e-116 388.9 4.0 7.6e-116 388.6 4.0 1.1 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor DIOX_N PF14226.6 OAP54404.1 - 1.3e-23 84.0 0.0 3.4e-23 82.6 0.0 1.7 1 1 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OAP54404.1 - 1.2e-17 64.2 0.0 2e-17 63.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily AMP-binding PF00501.28 OAP54405.1 - 1.5e-24 86.4 0.0 5.6e-24 84.5 0.0 1.7 1 1 0 1 1 1 1 AMP-binding enzyme Glyco_hydro_15 PF00723.21 OAP54406.1 - 1.6e-72 244.8 0.0 1.9e-72 244.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.19 OAP54406.1 - 4.5e-12 45.7 0.1 9.2e-12 44.7 0.1 1.5 1 0 0 1 1 1 1 Starch binding domain Aldo_ket_red PF00248.21 OAP54407.1 - 2.7e-66 223.8 0.0 2.7e-65 220.5 0.0 1.9 2 0 0 2 2 2 2 Aldo/keto reductase family zinc_ribbon_6 PF14599.6 OAP54408.1 - 2.4e-26 91.5 1.9 2.4e-26 91.5 1.9 3.6 3 2 1 4 4 4 1 Zinc-ribbon zf-CHY PF05495.12 OAP54408.1 - 6.8e-19 68.1 22.3 6.8e-19 68.1 22.3 3.4 3 0 0 3 3 3 2 CHY zinc finger zf-RING_2 PF13639.6 OAP54408.1 - 4.8e-08 33.2 10.6 4.8e-08 33.2 10.6 5.7 2 2 4 6 6 6 1 Ring finger domain zf-RING_5 PF14634.6 OAP54408.1 - 0.00017 21.4 8.6 0.00017 21.4 8.6 6.4 5 1 2 7 7 7 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 OAP54408.1 - 0.00038 20.3 9.1 0.00038 20.3 9.1 6.0 3 2 2 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OAP54408.1 - 0.0008 19.2 9.6 0.0008 19.2 9.6 5.9 4 4 3 7 7 7 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OAP54408.1 - 0.014 15.3 10.0 0.014 15.3 10.0 5.6 4 1 1 5 5 5 0 Prokaryotic RING finger family 4 Zn-C2H2_12 PF18112.1 OAP54408.1 - 2.4 8.7 9.6 5.1 7.7 0.1 3.6 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain Acyl_transf_1 PF00698.21 OAP54409.1 - 6e-20 72.0 0.0 1.4e-14 54.4 0.0 2.1 1 1 1 2 2 2 2 Acyl transferase domain Git3 PF11710.8 OAP54410.1 - 8.1e-23 81.3 15.0 3e-22 79.4 15.0 1.8 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.21 OAP54410.1 - 7.2e-09 35.4 11.0 1e-08 34.9 11.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) GPR_Gpa2_C PF11970.8 OAP54410.1 - 5.4e-06 26.4 0.4 5.4e-06 26.4 0.4 2.3 2 1 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term Dicty_CAR PF05462.11 OAP54410.1 - 0.00099 18.3 10.0 0.00099 18.3 10.0 1.6 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor FAD_binding_3 PF01494.19 OAP54411.1 - 4e-79 266.4 0.0 5.2e-79 266.0 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 OAP54411.1 - 4.3e-05 22.9 0.0 0.00095 18.5 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAP54411.1 - 7.5e-05 23.2 0.0 0.011 16.2 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAP54411.1 - 0.00017 21.3 0.4 0.018 14.6 0.1 2.7 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAP54411.1 - 0.00029 21.0 0.1 0.00074 19.7 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 OAP54411.1 - 0.0016 17.6 0.1 0.019 14.1 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 OAP54411.1 - 0.0048 16.0 0.1 0.012 14.7 0.1 1.7 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 OAP54411.1 - 0.0056 16.0 0.0 0.0096 15.2 0.0 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_7 PF13241.6 OAP54411.1 - 0.05 14.0 0.0 0.13 12.7 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox_3 PF13738.6 OAP54411.1 - 0.084 12.1 0.1 0.24 10.6 0.2 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OAP54411.1 - 0.23 10.5 0.1 0.33 10.0 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A AFG1_ATPase PF03969.16 OAP54414.1 - 7.8e-56 189.5 0.5 1.1e-23 83.8 0.0 5.0 4 1 1 5 5 5 4 AFG1-like ATPase AAA_16 PF13191.6 OAP54414.1 - 0.00061 20.2 0.1 0.0072 16.7 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 OAP54414.1 - 0.015 15.5 0.0 0.037 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 OAP54414.1 - 0.042 13.6 0.0 0.097 12.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATPase_2 PF01637.18 OAP54414.1 - 0.054 13.4 0.0 0.095 12.6 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 OAP54414.1 - 0.15 11.7 0.0 0.36 10.5 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain APS_kinase PF01583.20 OAP54415.1 - 2.4e-68 229.0 0.0 3e-68 228.7 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.6 OAP54415.1 - 1.3e-05 25.4 0.0 2.3e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 OAP54415.1 - 0.00048 20.7 0.0 0.00062 20.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 OAP54415.1 - 0.01 15.3 0.0 0.014 14.9 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_29 PF13555.6 OAP54415.1 - 0.011 15.4 0.0 0.019 14.7 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 OAP54415.1 - 0.028 13.7 0.0 0.049 12.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin CPT PF07931.12 OAP54415.1 - 0.074 12.9 0.0 0.25 11.1 0.0 1.9 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_16 PF13191.6 OAP54415.1 - 0.079 13.3 0.0 0.1 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 OAP54415.1 - 0.17 12.4 0.0 0.28 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Atu4866 PF11512.8 OAP54415.1 - 0.2 12.0 0.0 13 6.3 0.0 2.9 3 0 0 3 3 3 0 Agrobacterium tumefaciens protein Atu4866 UPF0029 PF01205.19 OAP54417.1 - 2.7e-20 72.7 0.1 1.1e-19 70.7 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized protein family UPF0029 Mucin PF01456.17 OAP54417.1 - 1.7 8.6 24.1 5.5 7.0 16.6 3.0 3 0 0 3 3 3 0 Mucin-like glycoprotein Ring_hydroxyl_A PF00848.19 OAP54418.1 - 6.5e-22 78.6 0.0 3.6e-11 43.4 0.0 2.2 1 1 1 2 2 2 2 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.26 OAP54419.1 - 3.8e-17 62.0 0.1 7.6e-17 61.0 0.1 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Ring_hydroxyl_A PF00848.19 OAP54419.1 - 0.012 15.6 0.2 0.067 13.1 0.0 2.0 2 0 0 2 2 2 0 Ring hydroxylating alpha subunit (catalytic domain) Pre-PUA PF17832.1 OAP54420.1 - 2.6e-24 85.7 0.1 3.7e-24 85.2 0.1 1.2 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 OAP54420.1 - 1.1e-13 50.9 0.3 1.7e-13 50.3 0.3 1.3 1 0 0 1 1 1 1 PUA domain DUF1947 PF09183.10 OAP54420.1 - 0.0079 16.5 0.1 0.014 15.6 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1947) La PF05383.17 OAP54421.1 - 3.6e-20 71.8 0.1 6.3e-20 71.0 0.1 1.4 1 0 0 1 1 1 1 La domain NPR3 PF03666.13 OAP54422.1 - 1.2e-136 456.3 0.0 1.2e-136 456.3 0.0 2.4 2 1 0 2 2 2 1 Nitrogen Permease regulator of amino acid transport activity 3 peroxidase PF00141.23 OAP54423.1 - 3.3e-44 151.3 0.0 4.8e-44 150.8 0.0 1.2 1 0 0 1 1 1 1 Peroxidase MFS_1 PF07690.16 OAP54425.1 - 2.8e-33 115.3 49.2 8.5e-33 113.7 49.5 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily ATP_synth_reg PF14960.6 OAP54425.1 - 1.6 8.3 3.5 2.3 7.8 0.0 2.6 3 0 0 3 3 3 0 ATP synthase regulation MARVEL PF01284.23 OAP54426.1 - 0.037 14.1 18.1 0.13 12.3 18.0 1.8 1 1 0 1 1 1 0 Membrane-associating domain DUF417 PF04224.12 OAP54426.1 - 0.084 12.4 0.3 0.15 11.6 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF417 Aldo_ket_red PF00248.21 OAP54427.1 - 1.7e-52 178.5 0.0 2.5e-52 177.9 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family PAP2 PF01569.21 OAP54428.1 - 1.3e-25 89.8 1.1 1.9e-25 89.2 0.2 1.8 2 0 0 2 2 2 1 PAP2 superfamily DUF3176 PF11374.8 OAP54431.1 - 9.6e-08 32.2 12.1 2.8e-06 27.5 11.9 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) Aminotran_4 PF01063.19 OAP54432.1 - 1.3e-43 149.4 0.0 1.6e-43 149.2 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV Sulfatase PF00884.23 OAP54436.1 - 1e-55 189.4 2.6 1.4e-55 188.9 2.6 1.2 1 0 0 1 1 1 1 Sulfatase DUF4976 PF16347.5 OAP54436.1 - 5.6e-05 23.3 0.0 0.00011 22.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4976) Phosphodiest PF01663.22 OAP54436.1 - 0.0062 16.2 0.3 0.94 9.0 0.4 2.1 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase WD40 PF00400.32 OAP54437.1 - 3.9e-22 78.1 11.6 2.5e-05 24.9 0.4 7.0 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAP54437.1 - 2.1e-14 53.5 1.1 0.066 13.5 0.2 6.2 1 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OAP54437.1 - 4.4e-06 26.7 0.0 0.0026 17.7 0.0 2.8 2 2 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 OAP54437.1 - 1.7e-05 23.6 0.0 0.00035 19.2 0.0 2.2 2 0 0 2 2 2 1 Cytochrome D1 heme domain Coatomer_WDAD PF04053.14 OAP54437.1 - 0.0068 15.5 0.0 0.49 9.4 0.0 2.4 2 0 0 2 2 2 2 Coatomer WD associated region PD40 PF07676.12 OAP54437.1 - 0.016 15.1 1.5 2.1 8.4 0.3 3.7 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Fungal_trans PF04082.18 OAP54438.1 - 9.4e-21 74.0 0.1 1.7e-20 73.2 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP54438.1 - 3.5e-09 36.6 12.5 6.8e-09 35.7 12.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldo_ket_red PF00248.21 OAP54439.1 - 8.4e-49 166.3 0.0 4.4e-47 160.7 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family UDPGT PF00201.18 OAP54439.1 - 0.049 12.4 0.0 0.07 11.9 0.0 1.1 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase Nefa_Nip30_N PF10187.9 OAP54440.1 - 1.5e-32 112.0 4.7 1.5e-32 112.0 4.7 2.2 2 0 0 2 2 2 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 DUF572 PF04502.13 OAP54440.1 - 0.023 14.3 11.4 0.03 14.0 11.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) BRF1 PF07741.13 OAP54440.1 - 5.2 7.5 11.9 0.54 10.6 6.4 2.0 2 0 0 2 2 2 0 Brf1-like TBP-binding domain DUF5383 PF17355.2 OAP54440.1 - 5.6 7.3 8.3 1.4 9.3 3.9 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5383) SMN PF06003.12 OAP54442.1 - 0.0004 19.7 12.7 0.0032 16.8 2.0 2.9 1 1 2 3 3 3 3 Survival motor neuron protein (SMN) V-ATPase_C PF03223.15 OAP54443.1 - 3.3e-122 408.5 0.2 3.7e-122 408.3 0.2 1.0 1 0 0 1 1 1 1 V-ATPase subunit C Mad3_BUB1_I PF08311.12 OAP54443.1 - 0.06 13.3 0.2 0.12 12.4 0.2 1.4 1 0 0 1 1 1 0 Mad3/BUB1 homology region 1 DUF4983 PF16356.5 OAP54443.1 - 0.12 13.2 0.0 0.26 12.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4983) peroxidase PF00141.23 OAP54444.1 - 6.2e-87 291.1 0.0 8.4e-45 153.2 0.0 2.4 2 0 0 2 2 2 2 Peroxidase GST_C_3 PF14497.6 OAP54444.1 - 0.0082 16.3 0.0 3.8 7.8 0.0 2.5 2 0 0 2 2 2 2 Glutathione S-transferase, C-terminal domain 4HBT PF03061.22 OAP54445.1 - 1.3e-10 41.5 0.0 2.3e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily Cation_ATPase_C PF00689.21 OAP54446.1 - 2.5e-47 160.9 8.5 2.5e-47 160.9 8.5 2.4 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 OAP54446.1 - 5e-36 123.9 0.5 5e-36 123.9 0.5 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 OAP54446.1 - 1.3e-21 76.5 0.0 2.3e-21 75.6 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 OAP54446.1 - 2.6e-19 70.4 2.1 1.3e-18 68.1 2.1 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 OAP54446.1 - 8.4e-09 35.0 0.2 5.2e-08 32.5 0.0 2.3 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 OAP54446.1 - 2.8e-05 24.0 0.6 6.9e-05 22.7 0.5 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase LptF_LptG PF03739.14 OAP54446.1 - 0.019 13.8 5.2 0.063 12.1 3.7 2.2 2 0 0 2 2 2 0 Lipopolysaccharide export system permease LptF/LptG HD PF01966.22 OAP54447.1 - 0.0028 17.9 0.0 0.0052 17.0 0.0 1.6 1 1 0 1 1 1 1 HD domain Nup84_Nup100 PF04121.13 OAP54448.1 - 2.3e-127 426.1 6.4 3.3e-127 425.6 6.4 1.2 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 DcuA_DcuB PF03605.14 OAP54449.1 - 0.098 11.5 1.3 0.12 11.2 1.3 1.1 1 0 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter PvlArgDC PF01862.16 OAP54449.1 - 0.5 10.1 1.8 0.83 9.4 1.8 1.3 1 0 0 1 1 1 0 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) Ligase_CoA PF00549.19 OAP54450.1 - 2.7e-33 114.9 2.1 1.4e-15 57.5 0.2 2.4 2 0 0 2 2 2 2 CoA-ligase CoA_binding PF02629.19 OAP54450.1 - 2.2e-12 47.5 0.2 8.1e-12 45.7 0.2 2.1 1 0 0 1 1 1 1 CoA binding domain Succ_CoA_lig PF13607.6 OAP54450.1 - 8.6e-09 35.3 0.4 1.8e-06 27.8 0.0 2.6 2 0 0 2 2 2 2 Succinyl-CoA ligase like flavodoxin domain Aldedh PF00171.22 OAP54452.1 - 6.8e-111 371.0 0.0 8.6e-111 370.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Tubulin PF00091.25 OAP54453.1 - 4.1e-68 229.5 0.0 9.9e-68 228.2 0.0 1.6 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 OAP54453.1 - 2.7e-43 147.1 0.1 4.5e-43 146.4 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 OAP54453.1 - 5.9e-05 23.4 0.0 0.00015 22.0 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 OAP54453.1 - 0.0005 19.4 0.0 0.022 14.0 0.0 2.1 2 0 0 2 2 2 1 Tubulin like Tubulin_3 PF14881.6 OAP54453.1 - 0.0027 17.4 0.0 0.0051 16.5 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Rad60-SLD PF11976.8 OAP54454.1 - 7.2e-20 70.6 0.2 9e-20 70.3 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 OAP54454.1 - 1.8e-10 40.4 0.1 2.1e-10 40.2 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin family 14-3-3 PF00244.20 OAP54455.1 - 9.1e-08 31.9 0.0 3.9e-07 29.8 0.0 1.8 2 0 0 2 2 2 1 14-3-3 protein LsmAD PF06741.13 OAP54456.1 - 1.6e-29 102.2 4.7 3.7e-29 101.1 4.7 1.7 1 0 0 1 1 1 1 LsmAD domain SM-ATX PF14438.6 OAP54456.1 - 1.7e-14 53.7 0.0 3.7e-14 52.6 0.0 1.6 1 0 0 1 1 1 1 Ataxin 2 SM domain Pkinase PF00069.25 OAP54457.1 - 1.2e-69 234.6 0.0 1.7e-69 234.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP54457.1 - 3.6e-39 134.6 0.0 5.5e-39 134.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 OAP54457.1 - 1.6e-14 53.4 0.1 3.4e-14 52.4 0.1 1.6 1 0 0 1 1 1 1 Kinase associated domain 1 Kdo PF06293.14 OAP54457.1 - 6.9e-06 25.6 0.1 1.2e-05 24.7 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OAP54457.1 - 1.5e-05 24.5 0.0 7.9e-05 22.1 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 OAP54457.1 - 2.3e-05 23.5 0.0 3.6e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OAP54457.1 - 0.00062 19.8 0.1 0.0075 16.2 0.1 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 OAP54457.1 - 0.15 11.7 0.0 0.31 10.6 0.0 1.5 1 0 0 1 1 1 0 RIO1 family YrbL-PhoP_reg PF10707.9 OAP54457.1 - 0.17 11.4 0.0 0.33 10.5 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL DUF1604 PF07713.13 OAP54458.1 - 1e-41 140.6 2.3 2.1e-41 139.6 1.3 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1604) G-patch PF01585.23 OAP54458.1 - 2.4e-07 30.5 0.3 1.7e-06 27.8 0.1 2.4 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 OAP54458.1 - 0.0034 17.4 0.2 0.021 14.9 0.2 2.4 1 1 0 1 1 1 1 G-patch domain UAA PF08449.11 OAP54459.1 - 2.5e-46 158.3 9.6 3.2e-46 157.9 9.6 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 OAP54459.1 - 1.4e-07 31.7 26.2 5.5e-07 29.8 7.8 3.4 3 1 0 3 3 3 2 EamA-like transporter family Nuc_sug_transp PF04142.15 OAP54459.1 - 1.8e-05 24.1 1.4 0.063 12.4 0.1 2.2 2 0 0 2 2 2 2 Nucleotide-sugar transporter TPT PF03151.16 OAP54459.1 - 0.032 13.6 8.2 0.75 9.1 0.4 2.2 2 0 0 2 2 2 0 Triose-phosphate Transporter family TPR_12 PF13424.6 OAP54460.1 - 3.1e-08 33.8 0.0 1.4e-06 28.5 0.0 3.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 OAP54460.1 - 1.2e-05 25.7 0.3 0.09 13.6 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_4 PF07721.14 OAP54460.1 - 3.8e-05 23.9 0.4 0.0096 16.5 0.3 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 OAP54460.1 - 0.00016 21.4 0.0 0.00016 21.4 0.0 3.7 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 OAP54460.1 - 0.00022 21.7 0.0 0.021 15.4 0.0 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 OAP54460.1 - 0.0094 16.0 0.1 0.12 12.6 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat FAD_binding_1 PF00667.20 OAP54460.1 - 0.013 15.1 0.1 0.031 13.8 0.1 1.6 1 0 0 1 1 1 0 FAD binding domain TPR_7 PF13176.6 OAP54460.1 - 0.018 15.0 0.1 0.23 11.6 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 OAP54460.1 - 0.036 14.7 0.5 0.79 10.4 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 OAP54460.1 - 0.077 13.2 0.2 0.26 11.5 0.1 2.0 2 0 0 2 2 1 0 Anaphase-promoting complex, cyclosome, subunit 3 Pam16 PF03656.13 OAP54460.1 - 0.14 12.2 0.0 0.4 10.7 0.0 1.7 1 0 0 1 1 1 0 Pam16 TPR_6 PF13174.6 OAP54460.1 - 0.14 12.8 0.7 1 10.2 0.4 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_MalT PF17874.1 OAP54460.1 - 0.22 10.8 4.5 1.3 8.3 0.7 2.8 2 1 1 3 3 3 0 MalT-like TPR region Gryzun PF07919.12 OAP54461.1 - 1.2e-171 572.4 0.0 1.5e-171 572.1 0.0 1.1 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi Foie-gras_1 PF11817.8 OAP54461.1 - 1.3e-78 264.2 0.9 1.8e-72 244.1 0.9 2.2 2 0 0 2 2 2 2 Foie gras liver health family 1 PEMT PF04191.13 OAP54462.1 - 1.1e-31 109.4 2.2 2.4e-31 108.3 2.2 1.5 1 0 0 1 1 1 1 Phospholipid methyltransferase RXT2_N PF08595.11 OAP54463.1 - 3.2e-38 131.2 0.0 3.2e-38 131.2 0.0 3.0 3 1 0 3 3 3 1 RXT2-like, N-terminal CK_II_beta PF01214.18 OAP54464.1 - 1.2e-77 259.8 0.1 1.7e-77 259.4 0.1 1.2 1 0 0 1 1 1 1 Casein kinase II regulatory subunit ANAPC5 PF12862.7 OAP54464.1 - 0.053 13.6 0.2 1.6 8.9 0.0 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 5 MFS_1 PF07690.16 OAP54466.1 - 9.3e-30 103.7 27.7 9.3e-30 103.7 27.7 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Ribonuc_P_40 PF08584.11 OAP54467.1 - 5.9e-54 183.3 0.0 7.7e-54 182.9 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit COX17 PF05051.13 OAP54468.1 - 0.0058 17.0 0.2 0.14 12.5 0.0 2.1 2 0 0 2 2 2 1 Cytochrome C oxidase copper chaperone (COX17) Pet191_N PF10203.9 OAP54468.1 - 0.044 14.1 2.4 2 8.8 1.4 2.1 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 CHCH PF06747.13 OAP54468.1 - 0.074 13.2 0.1 0.12 12.5 0.1 1.4 1 0 0 1 1 1 0 CHCH domain GDH_N PF12466.8 OAP54468.1 - 0.084 13.1 0.0 0.11 12.8 0.0 1.2 1 0 0 1 1 1 0 Glutamate dehydrogenase N terminal VGLL4 PF15245.6 OAP54470.1 - 0.022 14.9 1.1 0.025 14.6 1.1 1.0 1 0 0 1 1 1 0 Transcription cofactor vestigial-like protein 4 BPL_LplA_LipB PF03099.19 OAP54471.1 - 0.021 14.7 0.0 0.048 13.6 0.0 1.6 1 1 0 1 1 1 0 Biotin/lipoate A/B protein ligase family Peptidase_C65 PF10275.9 OAP54472.1 - 5.6e-61 206.1 0.0 7.6e-61 205.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase C65 Otubain PCI PF01399.27 OAP54473.1 - 2.6e-22 79.3 0.7 7.9e-22 77.8 0.7 1.9 1 0 0 1 1 1 1 PCI domain TPR_12 PF13424.6 OAP54473.1 - 0.0011 19.3 0.4 0.72 10.2 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 OAP54473.1 - 0.01 15.9 4.1 0.14 12.4 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 OAP54473.1 - 0.03 14.3 0.3 0.94 9.7 0.1 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 OAP54473.1 - 0.061 13.0 0.1 0.061 13.0 0.1 2.2 2 0 0 2 2 2 0 TPR repeat HTH_9 PF08221.11 OAP54473.1 - 0.063 13.4 0.1 0.14 12.3 0.1 1.5 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 helix-turn-helix domain RPN6_N PF18055.1 OAP54473.1 - 0.47 10.8 3.4 16 5.9 0.9 3.3 3 0 0 3 3 3 0 26S proteasome regulatory subunit RPN6 N-terminal domain TPR_8 PF13181.6 OAP54473.1 - 2 8.8 6.7 17 5.9 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 OAP54473.1 - 2.2 8.3 8.2 0.32 10.9 0.2 3.6 4 1 1 5 5 5 0 Tetratricopeptide repeat CWC25 PF12542.8 OAP54474.1 - 9.3e-27 93.9 1.0 9.3e-27 93.9 1.0 2.3 1 1 1 2 2 2 1 Pre-mRNA splicing factor Cir_N PF10197.9 OAP54474.1 - 2e-14 53.5 10.4 2e-14 53.5 10.4 2.4 2 1 1 3 3 3 1 N-terminal domain of CBF1 interacting co-repressor CIR DUF572 PF04502.13 OAP54474.1 - 0.9 9.1 5.8 1.3 8.5 5.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Ank_2 PF12796.7 OAP54476.1 - 1e-26 93.3 0.0 3.2e-14 53.3 0.0 3.6 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAP54476.1 - 1.4e-20 73.3 0.2 1.5e-11 44.6 0.0 4.0 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 OAP54476.1 - 2.4e-20 72.0 0.0 9.2e-06 25.9 0.0 3.9 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 OAP54476.1 - 3.8e-20 69.8 0.3 0.00017 21.8 0.0 4.6 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 OAP54476.1 - 2.5e-14 53.1 0.3 0.0016 18.7 0.0 3.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) NACHT PF05729.12 OAP54476.1 - 1.4e-08 34.8 0.0 3.4e-08 33.6 0.0 1.7 1 0 0 1 1 1 1 NACHT domain SpoU_sub_bind PF08032.12 OAP54476.1 - 0.019 15.2 0.1 30 5.0 0.1 4.0 3 1 1 4 4 4 0 RNA 2'-O ribose methyltransferase substrate binding AAA_16 PF13191.6 OAP54476.1 - 0.086 13.2 0.0 0.31 11.4 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain SesA PF17107.5 OAP54477.1 - 5.2e-43 146.1 0.5 8.1e-43 145.5 0.5 1.3 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases NACHT_sigma PF17106.5 OAP54477.1 - 1.5e-05 25.1 9.4 2.4e-05 24.4 9.4 1.4 1 0 0 1 1 1 1 Sigma domain on NACHT-NTPases CHIP_TPR_N PF18391.1 OAP54477.1 - 0.016 16.0 0.6 0.029 15.1 0.6 1.6 1 0 0 1 1 1 0 CHIP N-terminal tetratricopeptide repeat domain Helo_like_N PF17111.5 OAP54477.1 - 0.021 14.2 0.1 0.038 13.4 0.1 1.3 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins Translin PF01997.16 OAP54477.1 - 0.06 13.3 0.1 0.092 12.7 0.1 1.3 1 0 0 1 1 1 0 Translin family DUF1864 PF08933.11 OAP54477.1 - 0.072 11.8 0.1 0.092 11.5 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1864) SLATT_1 PF18181.1 OAP54477.1 - 0.13 12.2 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 1 DUF2802 PF10975.8 OAP54477.1 - 0.27 11.4 2.4 0.67 10.1 0.0 2.7 4 0 0 4 4 4 0 Protein of unknown function (DUF2802) Amidase PF01425.21 OAP54478.1 - 2.4e-41 142.2 0.0 5.4e-37 127.8 0.1 2.2 2 0 0 2 2 2 2 Amidase ATP12 PF07542.11 OAP54478.1 - 0.16 12.1 0.0 0.31 11.1 0.0 1.4 1 0 0 1 1 1 0 ATP12 chaperone protein WD40 PF00400.32 OAP54479.1 - 5.9e-17 61.7 0.1 2.6e-12 47.0 0.1 2.9 2 0 0 2 2 2 2 WD domain, G-beta repeat NACHT PF05729.12 OAP54479.1 - 1.1e-07 32.0 0.0 3e-07 30.5 0.0 1.8 1 0 0 1 1 1 1 NACHT domain ANAPC4_WD40 PF12894.7 OAP54479.1 - 6.6e-07 29.5 0.0 1.3e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain AAA_16 PF13191.6 OAP54479.1 - 1.4e-05 25.6 0.0 1.4e-05 25.6 0.0 2.4 2 1 0 2 2 1 1 AAA ATPase domain NB-ARC PF00931.22 OAP54479.1 - 0.0012 18.0 0.0 0.0032 16.7 0.0 1.7 1 0 0 1 1 1 1 NB-ARC domain CDC45 PF02724.14 OAP54479.1 - 0.004 15.5 18.1 0.006 15.0 18.1 1.2 1 0 0 1 1 1 1 CDC45-like protein AAA_23 PF13476.6 OAP54479.1 - 0.0093 16.5 5.2 0.23 11.9 3.3 2.3 2 0 0 2 2 2 1 AAA domain Ge1_WD40 PF16529.5 OAP54479.1 - 0.018 14.0 0.0 0.031 13.3 0.0 1.3 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 OAP54479.1 - 0.024 14.0 0.0 0.21 10.9 0.0 2.0 2 0 0 2 2 2 0 WD40-like domain Rpn3_C PF08375.11 OAP54479.1 - 0.032 14.7 11.9 1.3 9.5 13.9 2.3 2 0 0 2 2 2 0 Proteasome regulatory subunit C-terminal APS_kinase PF01583.20 OAP54479.1 - 0.035 14.0 0.1 0.069 13.0 0.1 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase PPP4R2 PF09184.11 OAP54479.1 - 0.044 13.4 17.7 0.071 12.7 17.7 1.2 1 0 0 1 1 1 0 PPP4R2 AAA_22 PF13401.6 OAP54479.1 - 0.054 13.8 0.1 0.3 11.3 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA PF00004.29 OAP54479.1 - 0.063 13.7 0.2 0.28 11.6 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PIF1 PF05970.14 OAP54479.1 - 0.18 11.0 0.0 0.27 10.4 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase SurE PF01975.17 OAP54479.1 - 0.2 11.4 0.0 0.41 10.4 0.0 1.4 1 0 0 1 1 1 0 Survival protein SurE Presenilin PF01080.17 OAP54479.1 - 0.21 10.3 2.3 0.27 9.9 2.3 1.2 1 0 0 1 1 1 0 Presenilin NOA36 PF06524.12 OAP54479.1 - 0.73 9.1 16.5 1.2 8.4 16.5 1.2 1 0 0 1 1 1 0 NOA36 protein DUF913 PF06025.12 OAP54479.1 - 0.8 8.6 4.9 3 6.7 4.6 1.9 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) RNA_pol_Rpc4 PF05132.14 OAP54479.1 - 0.97 9.8 3.9 1.5 9.2 3.9 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF2052 PF09747.9 OAP54479.1 - 1 9.5 17.5 1.8 8.7 17.5 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) SDA1 PF05285.12 OAP54479.1 - 1.5 8.2 22.4 2 7.8 22.4 1.1 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 OAP54479.1 - 1.9 7.8 13.9 2.6 7.3 13.9 1.1 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 OAP54479.1 - 3.7 5.7 22.9 3.4 5.7 20.8 1.7 2 0 0 2 2 2 0 Nop14-like family Mpp10 PF04006.12 OAP54479.1 - 3.9 5.8 22.5 5.6 5.3 22.5 1.1 1 0 0 1 1 1 0 Mpp10 protein TLP-20 PF06088.11 OAP54479.1 - 3.9 7.3 7.1 6.7 6.6 7.1 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) CobT PF06213.12 OAP54479.1 - 4.2 6.7 19.2 7.8 5.8 19.2 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT RR_TM4-6 PF06459.12 OAP54479.1 - 6 6.6 12.7 9.4 6.0 12.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF5523 PF17661.1 OAP54479.1 - 6.6 6.3 19.6 11 5.6 19.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5523) Paf1 PF03985.13 OAP54479.1 - 7.8 5.4 23.5 12 4.8 23.5 1.1 1 0 0 1 1 1 0 Paf1 RNA_polI_A34 PF08208.11 OAP54479.1 - 8.3 6.5 14.2 13 5.8 14.2 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Sigma70_ner PF04546.13 OAP54479.1 - 9.3 6.1 18.6 19 5.1 18.6 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region Helo_like_N PF17111.5 OAP54480.1 - 5.1e-20 71.7 5.5 7.7e-20 71.2 5.5 1.3 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins DUF2001 PF09393.10 OAP54480.1 - 0.0018 18.3 0.2 0.0042 17.1 0.2 1.6 1 0 0 1 1 1 1 Phage tail tube protein PTR2 PF00854.21 OAP54481.1 - 2.2e-79 267.1 8.7 3e-79 266.7 8.7 1.1 1 0 0 1 1 1 1 POT family MFS_1 PF07690.16 OAP54481.1 - 4.1e-05 22.7 21.3 4.1e-05 22.7 21.3 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily DPM3 PF08285.11 OAP54481.1 - 0.15 12.3 2.8 8.6 6.6 0.3 3.0 2 0 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF4149 PF13664.6 OAP54481.1 - 0.25 11.7 6.3 7.1 7.0 0.1 3.4 3 1 1 4 4 4 0 Domain of unknown function (DUF4149) Ldh_1_C PF02866.18 OAP54482.1 - 4.6e-20 72.2 0.0 6.5e-20 71.7 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 OAP54482.1 - 3.9e-09 36.7 0.0 6e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Fungal_trans_2 PF11951.8 OAP54483.1 - 3e-11 42.8 0.0 1e-10 41.0 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Amino_oxidase PF01593.24 OAP54484.1 - 6.9e-57 193.7 0.1 8.4e-57 193.4 0.1 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OAP54484.1 - 8.4e-11 41.9 0.1 1.7e-10 41.0 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAP54484.1 - 1.5e-10 41.2 0.0 1.4e-05 24.9 0.0 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_oxidored PF12831.7 OAP54484.1 - 2e-07 30.7 0.0 6.4e-06 25.8 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 OAP54484.1 - 8.3e-07 28.5 0.1 1.4e-06 27.7 0.1 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 OAP54484.1 - 2.1e-05 23.8 0.1 3.8e-05 23.0 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 OAP54484.1 - 2.3e-05 23.8 0.0 0.0022 17.3 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAP54484.1 - 0.00058 19.2 0.0 0.55 9.4 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAP54484.1 - 0.00094 18.0 0.0 0.0046 15.7 0.0 1.8 2 0 0 2 2 2 1 HI0933-like protein Lycopene_cycl PF05834.12 OAP54484.1 - 0.0024 17.0 0.0 0.01 14.9 0.0 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein GIDA PF01134.22 OAP54484.1 - 0.0029 16.8 0.0 0.0087 15.2 0.0 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox PF00070.27 OAP54484.1 - 0.0086 16.6 0.0 0.099 13.2 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 OAP54484.1 - 0.045 13.0 0.5 0.094 11.9 0.5 1.5 1 0 0 1 1 1 0 FAD binding domain AA_permease_2 PF13520.6 OAP54485.1 - 4.3e-47 160.9 49.5 5.3e-47 160.6 49.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAP54485.1 - 6.7e-16 57.9 44.8 9.3e-16 57.5 44.8 1.1 1 0 0 1 1 1 1 Amino acid permease AMP-binding PF00501.28 OAP54486.1 - 1.9e-41 142.1 0.0 3.1e-41 141.4 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Fungal_trans PF04082.18 OAP54486.1 - 3.3e-10 39.5 0.0 5.2e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain AMP-binding_C PF13193.6 OAP54486.1 - 0.00012 23.0 0.0 0.00034 21.5 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 OAP54486.1 - 0.00042 20.2 0.1 0.0024 17.8 0.1 2.4 1 1 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus Zn_clus PF00172.18 OAP54486.1 - 0.15 12.2 2.4 0.3 11.2 2.4 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Acyl-CoA_dh_1 PF00441.24 OAP54487.1 - 6.8e-17 62.1 0.1 2.2e-16 60.4 0.1 1.9 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 OAP54487.1 - 5.4e-11 42.5 0.0 1.4e-10 41.2 0.0 1.8 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain AidB_N PF18158.1 OAP54487.1 - 9.7e-05 22.3 0.2 0.0014 18.6 0.1 2.7 2 1 2 4 4 4 1 Adaptive response protein AidB N-terminal domain HNF_C PF09354.10 OAP54487.1 - 0.072 14.2 0.1 0.19 12.8 0.1 1.7 1 0 0 1 1 1 0 HNF3 C-terminal domain 4HBT_3 PF13622.6 OAP54488.1 - 1.8e-22 80.8 1.0 2.1e-22 80.6 1.0 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 OAP54488.1 - 0.002 18.0 0.1 0.0026 17.6 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA thioesterase ACOX PF01756.19 OAP54489.1 - 2.1e-48 164.3 0.2 7.4e-48 162.5 0.1 1.8 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 OAP54489.1 - 3.1e-27 95.6 0.2 7.2e-27 94.4 0.2 1.7 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 OAP54489.1 - 1.3e-13 51.0 0.0 4e-13 49.4 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 OAP54489.1 - 0.00022 21.5 0.0 0.0093 16.2 0.0 2.4 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain DAGK_cat PF00781.24 OAP54490.1 - 4.9e-23 81.1 0.1 8.8e-23 80.3 0.1 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Pkinase PF00069.25 OAP54491.1 - 4.7e-67 226.1 0.0 7.4e-67 225.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP54491.1 - 2.1e-35 122.3 0.0 3.6e-34 118.2 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAP54491.1 - 0.00012 21.5 0.1 0.00046 19.6 0.1 1.8 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 OAP54491.1 - 0.0016 18.4 0.0 0.0035 17.3 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 OAP54491.1 - 0.0089 15.1 0.0 0.016 14.3 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Pkinase_fungal PF17667.1 OAP54491.1 - 0.02 13.7 0.0 0.039 12.7 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Ammonium_transp PF00909.21 OAP54492.1 - 3.7e-119 398.0 32.4 4.1e-119 397.8 32.4 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DUF441 PF04284.13 OAP54492.1 - 0.12 12.3 3.2 0.53 10.3 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF441) Phage_holin_2_1 PF04971.12 OAP54492.1 - 7 6.7 7.7 1.4 9.0 0.8 3.2 2 1 0 2 2 2 0 Bacteriophage P21 holin S Kelch_5 PF13854.6 OAP54494.1 - 1.8e-10 40.6 0.5 1.8e-10 40.6 0.5 3.4 4 0 0 4 4 4 1 Kelch motif Kelch_3 PF13415.6 OAP54494.1 - 0.0082 16.4 10.0 0.75 10.2 0.1 4.0 4 0 0 4 4 4 2 Galactose oxidase, central domain DUF4448 PF14610.6 OAP54494.1 - 0.015 15.1 0.0 0.025 14.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DUF5023 PF16426.5 OAP54494.1 - 0.042 13.5 1.6 0.084 12.5 1.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5023) Alpha_GJ PF03229.13 OAP54494.1 - 0.12 12.9 2.4 0.14 12.7 0.3 2.3 2 0 0 2 2 2 0 Alphavirus glycoprotein J Kelch_6 PF13964.6 OAP54494.1 - 2 8.8 8.0 6.9 7.1 0.3 3.5 4 0 0 4 4 4 0 Kelch motif Kelch_1 PF01344.25 OAP54494.1 - 2.5 7.7 16.0 0.25 11.0 0.7 4.0 4 1 0 4 4 4 0 Kelch motif RRM_1 PF00076.22 OAP54495.1 - 4e-15 55.4 0.2 2e-06 27.5 0.0 3.0 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OAP54495.1 - 0.095 12.8 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif DUF3410 PF11890.8 OAP54496.1 - 0.1 12.4 0.1 4.1 7.3 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3410) Collagen PF01391.18 OAP54497.1 - 8.8e-06 25.4 9.2 2.9e-05 23.7 9.2 1.9 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Mpv17_PMP22 PF04117.12 OAP54498.1 - 1e-20 73.7 0.1 2.3e-20 72.6 0.1 1.6 1 0 0 1 1 1 1 Mpv17 / PMP22 family PGK PF00162.19 OAP54499.1 - 3.4e-150 500.2 0.6 3.9e-150 500.0 0.6 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase PA PF02225.22 OAP54499.1 - 0.0085 16.1 0.7 0.7 10.0 0.0 2.9 3 0 0 3 3 3 1 PA domain DUF3530 PF12048.8 OAP54499.1 - 0.15 11.5 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) DSS1_SEM1 PF05160.13 OAP54500.1 - 5.3e-24 84.0 12.3 7.4e-24 83.6 12.3 1.2 1 0 0 1 1 1 1 DSS1/SEM1 family DUF3808 PF10300.9 OAP54501.1 - 2.6e-135 451.8 0.0 3.7e-135 451.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) Acetyltransf_1 PF00583.25 OAP54502.1 - 2.5e-11 43.8 0.0 3.2e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OAP54502.1 - 4.3e-09 36.7 0.0 6.5e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OAP54502.1 - 1.4e-07 31.5 0.0 1.7e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAP54502.1 - 0.00014 21.8 0.0 0.00026 20.9 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 OAP54502.1 - 0.0062 16.6 0.0 0.0091 16.1 0.0 1.2 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.7 OAP54502.1 - 0.028 14.6 0.0 0.035 14.2 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 OAP54502.1 - 0.036 14.7 0.0 0.043 14.5 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain ELFV_dehydrog PF00208.21 OAP54503.1 - 1.3e-83 280.4 4.2 1.7e-83 280.1 4.2 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 OAP54503.1 - 1.4e-51 173.8 0.0 5.2e-51 171.9 0.0 2.0 2 0 0 2 2 2 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain CAMSAP_CKK PF08683.11 OAP54503.1 - 0.048 13.8 0.1 0.21 11.7 0.0 1.9 2 0 0 2 2 2 0 Microtubule-binding calmodulin-regulated spectrin-associated NAD_binding_7 PF13241.6 OAP54503.1 - 0.16 12.4 0.3 1.1 9.8 0.1 2.2 2 0 0 2 2 2 0 Putative NAD(P)-binding Nup160 PF11715.8 OAP54504.1 - 9.5e-107 357.9 2.3 1.3e-106 357.4 2.3 1.1 1 0 0 1 1 1 1 Nucleoporin Nup120/160 AGS_C PF18134.1 OAP54504.1 - 0.14 12.1 0.0 0.33 10.9 0.0 1.6 1 0 0 1 1 1 0 Adenylyl/Guanylyl and SMODS C-terminal sensor domain FF PF01846.19 OAP54505.1 - 7.6e-46 154.1 25.9 5e-15 55.4 0.8 7.2 7 1 0 7 7 7 5 FF domain WW PF00397.26 OAP54505.1 - 1.1e-16 60.6 16.4 1.1e-08 35.0 5.1 2.7 2 0 0 2 2 2 2 WW domain RhoGAP-FF1 PF16512.5 OAP54505.1 - 0.004 17.8 14.3 0.38 11.4 0.4 4.6 3 1 1 4 4 4 2 p190-A and -B Rho GAPs FF domain PTPlike_phytase PF14566.6 OAP54505.1 - 0.019 15.1 2.0 0.019 15.1 2.0 2.3 2 1 0 2 2 2 0 Inositol hexakisphosphate Trs65 PF12735.7 OAP54506.1 - 2.2e-65 221.1 0.0 4.6e-65 220.1 0.0 1.5 2 0 0 2 2 2 1 TRAPP trafficking subunit Trs65 SIP1 PF04938.12 OAP54508.1 - 3e-12 46.7 0.0 4e-11 43.1 0.0 2.0 2 0 0 2 2 2 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) PRIMA1 PF16101.5 OAP54509.1 - 0.028 14.5 0.2 0.028 14.5 0.2 1.8 1 1 1 2 2 2 0 Proline-rich membrane anchor 1 CAP_N PF01213.19 OAP54509.1 - 0.19 11.2 1.7 0.39 10.2 1.7 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal UL40 PF10682.9 OAP54509.1 - 0.42 10.3 3.5 0.22 11.2 1.1 1.7 2 0 0 2 2 2 0 Glycoprotein of human cytomegalovirus HHV-5 tRNA-synt_2 PF00152.20 OAP54511.1 - 2.4e-70 237.1 0.1 3.3e-70 236.7 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 OAP54511.1 - 3.4e-07 30.1 0.1 6.2e-07 29.3 0.1 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 OAP54511.1 - 0.059 12.8 0.2 3.8 6.9 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) NARP1 PF12569.8 OAP54511.1 - 0.17 10.7 10.8 0.25 10.2 10.8 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Abhydrolase_6 PF12697.7 OAP54512.1 - 5.4e-06 27.2 2.7 5.5e-06 27.1 0.7 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF676 PF05057.14 OAP54512.1 - 0.00011 21.8 0.0 0.00022 20.8 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 OAP54512.1 - 0.00042 20.1 1.4 0.00091 19.0 0.0 2.0 2 1 1 3 3 3 1 PGAP1-like protein Presenilin PF01080.17 OAP54512.1 - 9 4.9 6.0 14 4.3 6.0 1.2 1 0 0 1 1 1 0 Presenilin PX PF00787.24 OAP54513.1 - 3.1e-15 56.2 0.0 3.1e-14 52.9 0.0 2.1 2 0 0 2 2 2 1 PX domain Ku_PK_bind PF08785.11 OAP54514.1 - 4e-34 117.3 0.1 8e-34 116.4 0.1 1.5 1 0 0 1 1 1 1 Ku C terminal domain like Ku PF02735.16 OAP54514.1 - 1.6e-30 106.3 0.0 3.4e-30 105.3 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 OAP54514.1 - 2.4e-14 53.6 0.0 6.1e-14 52.3 0.0 1.7 1 1 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain VWA PF00092.28 OAP54514.1 - 4.5e-05 23.8 0.1 0.00018 21.8 0.0 2.0 2 0 0 2 2 2 1 von Willebrand factor type A domain DUF4149 PF13664.6 OAP54515.1 - 2.1e-26 92.2 1.1 2.1e-26 92.2 1.1 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) DUF1223 PF06764.11 OAP54517.1 - 4.7e-48 163.9 0.0 5.4e-48 163.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1223) bZIP_1 PF00170.21 OAP54518.1 - 1e-05 25.5 11.9 1e-05 25.5 11.9 2.5 2 1 1 3 3 3 1 bZIP transcription factor bZIP_Maf PF03131.17 OAP54518.1 - 0.0002 21.8 13.1 0.00057 20.3 13.0 1.9 1 1 0 1 1 1 1 bZIP Maf transcription factor bZIP_2 PF07716.15 OAP54518.1 - 0.0012 18.9 9.9 0.0012 18.9 9.9 3.1 2 1 1 3 3 3 1 Basic region leucine zipper Sel1 PF08238.12 OAP54519.1 - 1.9e-15 56.9 2.9 4.3e-05 24.0 0.0 4.1 4 1 0 4 4 4 3 Sel1 repeat DUF908 PF06012.12 OAP54519.1 - 0.25 10.7 2.1 0.27 10.6 1.4 1.4 1 1 0 1 1 1 0 Domain of Unknown Function (DUF908) F-box-like PF12937.7 OAP54520.1 - 4.3e-08 32.9 0.3 2.2e-07 30.7 0.2 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 OAP54520.1 - 7.8e-05 22.4 0.2 0.00021 21.1 0.0 1.8 2 0 0 2 2 2 1 F-box domain p450 PF00067.22 OAP54522.1 - 8.6e-60 202.8 0.0 1e-59 202.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FA_desaturase PF00487.24 OAP54523.1 - 0.011 15.6 1.7 0.024 14.5 1.3 1.7 1 1 0 1 1 1 0 Fatty acid desaturase SKG6 PF08693.10 OAP54524.1 - 0.039 13.4 0.0 0.064 12.7 0.0 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain SKG6 PF08693.10 OAP54525.1 - 2.5e-10 39.6 2.0 6.6e-10 38.2 2.0 1.8 1 0 0 1 1 1 1 Transmembrane alpha-helix domain VSP PF03302.13 OAP54525.1 - 0.00012 21.1 4.2 0.00012 21.1 4.2 1.5 1 1 1 2 2 2 1 Giardia variant-specific surface protein TMEM154 PF15102.6 OAP54525.1 - 0.00033 20.6 0.0 0.00033 20.6 0.0 3.3 1 1 1 2 2 2 1 TMEM154 protein family DUF4448 PF14610.6 OAP54525.1 - 0.00064 19.5 0.2 0.0016 18.2 0.2 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF4448) CD34_antigen PF06365.12 OAP54525.1 - 0.0068 16.0 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 CD34/Podocalyxin family SCF PF02404.15 OAP54525.1 - 0.083 12.2 0.2 0.13 11.5 0.2 1.2 1 0 0 1 1 1 0 Stem cell factor EphA2_TM PF14575.6 OAP54525.1 - 0.092 13.6 0.0 0.18 12.7 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF2681 PF10883.8 OAP54525.1 - 0.15 12.5 0.1 0.25 11.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) DUF5305 PF17231.2 OAP54525.1 - 5.3 6.4 11.3 18 4.6 0.1 2.3 1 1 0 2 2 2 0 Family of unknown function (DUF5305) PTS_2-RNA PF01885.16 OAP54526.1 - 5.7e-60 202.5 0.0 1.1e-59 201.6 0.0 1.4 1 1 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family Med8 PF10232.9 OAP54526.1 - 0.02 14.5 0.4 0.062 12.9 0.0 1.9 2 0 0 2 2 2 0 Mediator of RNA polymerase II transcription complex subunit 8 NigD_N PF12667.7 OAP54526.1 - 0.021 14.9 0.1 0.039 14.0 0.1 1.4 1 0 0 1 1 1 0 NigD-like N-terminal OB domain RNA_pol_Rpo13 PF12136.8 OAP54526.1 - 1.4 8.9 9.6 3 7.8 9.6 1.6 1 0 0 1 1 1 0 RNA polymerase Rpo13 subunit HTH domain Nop PF01798.18 OAP54527.1 - 1.6e-70 237.2 0.0 2.7e-70 236.5 0.0 1.4 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 OAP54527.1 - 2e-48 164.2 1.9 2e-48 164.2 1.9 2.2 3 0 0 3 3 3 1 Prp31 C terminal domain RRN3 PF05327.11 OAP54527.1 - 5.8 5.3 6.2 2.4 6.6 3.8 1.5 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 TPR_14 PF13428.6 OAP54528.1 - 4.1e-24 83.2 31.4 0.0029 18.3 0.2 12.8 5 2 9 14 14 14 6 Tetratricopeptide repeat HAT PF02184.16 OAP54528.1 - 1.6e-22 79.2 88.5 4.3e-15 55.4 4.1 14.2 15 1 0 15 15 15 4 HAT (Half-A-TPR) repeat TPR_19 PF14559.6 OAP54528.1 - 1.4e-21 76.7 0.0 4.7e-05 23.8 0.0 7.5 7 0 0 7 7 7 4 Tetratricopeptide repeat Suf PF05843.14 OAP54528.1 - 5.3e-15 56.2 30.1 0.00024 21.2 0.4 6.7 2 1 2 6 6 6 4 Suppressor of forked protein (Suf) TPR_17 PF13431.6 OAP54528.1 - 1.7e-09 37.4 5.7 0.021 15.2 0.0 7.6 9 0 0 9 9 7 2 Tetratricopeptide repeat TPR_2 PF07719.17 OAP54528.1 - 3.7e-09 36.0 21.6 1.1 9.5 0.0 10.1 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_8 PF13181.6 OAP54528.1 - 8.8e-07 28.7 14.0 7.8 7.0 0.0 9.2 10 0 0 10 10 8 1 Tetratricopeptide repeat TPR_6 PF13174.6 OAP54528.1 - 1.5e-06 28.4 18.8 2.9 8.7 0.1 8.9 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_15 PF13429.6 OAP54528.1 - 4.2e-06 26.2 17.3 0.14 11.3 3.4 5.9 2 1 5 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.6 OAP54528.1 - 0.00037 21.1 18.6 12 6.6 0.1 8.2 9 1 1 10 10 8 0 Tetratricopeptide repeat TPR_MalT PF17874.1 OAP54528.1 - 0.00042 19.8 0.3 0.02 14.3 0.0 3.2 3 0 0 3 3 3 1 MalT-like TPR region DUF3808 PF10300.9 OAP54528.1 - 0.06 12.1 1.0 0.15 10.8 0.3 1.9 1 1 0 2 2 2 0 Protein of unknown function (DUF3808) PPTA PF01239.22 OAP54528.1 - 0.069 12.9 1.1 9.7 6.1 0.2 2.6 2 0 0 2 2 2 0 Protein prenyltransferase alpha subunit repeat Fis1_TPR_C PF14853.6 OAP54528.1 - 0.48 10.5 14.0 17 5.6 0.9 5.9 7 0 0 7 7 6 0 Fis1 C-terminal tetratricopeptide repeat U3_assoc_6 PF08640.11 OAP54528.1 - 0.61 10.2 34.5 0.07 13.2 2.9 8.2 6 4 3 9 9 9 0 U3 small nucleolar RNA-associated protein 6 TPR_1 PF00515.28 OAP54528.1 - 2.3 8.2 12.4 37 4.3 0.1 5.9 8 0 0 8 8 7 0 Tetratricopeptide repeat NRDE-2 PF08424.10 OAP54528.1 - 2.7 7.0 32.9 1.7 7.7 0.0 7.1 2 2 3 6 6 6 0 NRDE-2, necessary for RNA interference NifW PF03206.14 OAP54528.1 - 6.3 7.4 6.3 4.7 7.8 0.1 3.6 4 0 0 4 4 3 0 Nitrogen fixation protein NifW TPR_12 PF13424.6 OAP54528.1 - 7.9 6.8 22.6 7 7.0 0.0 7.9 10 0 0 10 10 10 0 Tetratricopeptide repeat Kelch_6 PF13964.6 OAP54529.1 - 6.4e-06 26.3 6.7 0.0074 16.5 0.1 4.4 5 0 0 5 5 5 2 Kelch motif Kelch_5 PF13854.6 OAP54529.1 - 0.0047 16.9 5.0 0.049 13.6 0.3 3.4 3 0 0 3 3 3 1 Kelch motif DUF202 PF02656.15 OAP54529.1 - 0.067 13.6 0.1 0.14 12.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF202) Kelch_3 PF13415.6 OAP54529.1 - 0.14 12.5 0.2 0.14 12.5 0.2 3.9 4 0 0 4 4 4 0 Galactose oxidase, central domain Kelch_2 PF07646.15 OAP54529.1 - 5.9 7.0 9.9 45 4.2 0.0 4.9 5 0 0 5 5 5 0 Kelch motif Stb3 PF10330.9 OAP54530.1 - 5e-39 132.2 0.0 7.8e-39 131.6 0.0 1.3 1 0 0 1 1 1 1 Putative Sin3 binding protein ABC_tran PF00005.27 OAP54531.1 - 2.7e-34 118.6 0.0 3.5e-16 60.0 0.0 2.4 2 0 0 2 2 2 2 ABC transporter RLI PF04068.15 OAP54531.1 - 3e-14 52.6 5.5 3e-14 52.6 5.5 2.0 2 0 0 2 2 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI SMC_N PF02463.19 OAP54531.1 - 1.7e-11 44.0 1.8 0.0054 16.2 0.0 3.9 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 OAP54531.1 - 5.7e-10 39.5 6.5 0.049 13.4 0.0 4.2 2 2 2 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system Rad17 PF03215.15 OAP54531.1 - 4.9e-06 26.6 0.1 0.022 14.7 0.0 2.6 2 1 0 2 2 2 2 Rad17 P-loop domain AAA_15 PF13175.6 OAP54531.1 - 1.7e-05 24.8 0.3 0.22 11.2 0.0 3.2 3 1 0 3 3 2 2 AAA ATPase domain Fer4 PF00037.27 OAP54531.1 - 4.9e-05 23.0 2.6 4.9e-05 23.0 2.6 2.7 3 0 0 3 3 3 1 4Fe-4S binding domain AAA PF00004.29 OAP54531.1 - 7.1e-05 23.2 0.1 0.099 13.1 0.1 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 OAP54531.1 - 9.9e-05 22.3 0.0 0.39 10.6 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 OAP54531.1 - 0.00015 22.1 0.0 0.035 14.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_13 PF13166.6 OAP54531.1 - 0.00025 19.8 0.0 0.0006 18.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OAP54531.1 - 0.00029 21.3 0.0 0.63 10.4 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 OAP54531.1 - 0.00059 19.5 0.5 0.59 9.9 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_24 PF13479.6 OAP54531.1 - 0.0012 18.6 1.7 0.095 12.4 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 OAP54531.1 - 0.0018 18.8 0.0 2.9 8.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 OAP54531.1 - 0.0024 17.4 0.8 0.034 13.7 0.2 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region RNA_helicase PF00910.22 OAP54531.1 - 0.0028 18.0 0.7 1.2 9.6 0.0 3.0 3 0 0 3 3 2 1 RNA helicase Fer4_21 PF14697.6 OAP54531.1 - 0.0038 17.3 11.4 0.0077 16.3 11.4 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain SRP54 PF00448.22 OAP54531.1 - 0.005 16.5 3.5 0.085 12.5 0.1 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Fer4_6 PF12837.7 OAP54531.1 - 0.0087 16.1 12.2 0.02 15.0 2.2 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_28 PF13521.6 OAP54531.1 - 0.0087 16.3 0.0 1.9 8.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 OAP54531.1 - 0.0091 16.2 0.1 1.8 8.8 0.1 2.5 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 OAP54531.1 - 0.01 15.0 0.0 1.3 8.2 0.0 2.4 3 0 0 3 3 2 0 NB-ARC domain TsaE PF02367.17 OAP54531.1 - 0.014 15.4 0.2 0.18 11.8 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Fer4_10 PF13237.6 OAP54531.1 - 0.031 14.4 15.4 0.032 14.3 1.4 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain Thymidylate_kin PF02223.17 OAP54531.1 - 0.037 13.7 0.5 14 5.3 0.0 3.0 3 0 0 3 3 3 0 Thymidylate kinase NACHT PF05729.12 OAP54531.1 - 0.041 13.8 3.0 1.8 8.5 0.1 2.7 3 0 0 3 3 2 0 NACHT domain DLIC PF05783.11 OAP54531.1 - 0.044 12.6 0.1 0.076 11.8 0.1 1.3 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) AAA_23 PF13476.6 OAP54531.1 - 0.061 13.8 3.2 1.6 9.2 0.5 2.5 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 OAP54531.1 - 0.074 12.8 0.6 4.5 6.9 0.1 2.4 2 0 0 2 2 2 0 AAA domain Fer4_16 PF13484.6 OAP54531.1 - 0.078 13.9 0.3 0.078 13.9 0.3 2.7 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain Fer4_9 PF13187.6 OAP54531.1 - 0.081 13.1 11.3 0.18 12.0 11.3 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain VirE PF05272.11 OAP54531.1 - 0.082 12.6 0.0 6.1 6.5 0.0 2.4 2 0 0 2 2 2 0 Virulence-associated protein E DnaB_C PF03796.15 OAP54531.1 - 0.087 12.1 0.0 0.27 10.5 0.0 1.7 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain TniB PF05621.11 OAP54531.1 - 0.1 12.0 0.1 0.63 9.4 0.0 2.1 2 0 0 2 2 2 0 Bacterial TniB protein ATPase PF06745.13 OAP54531.1 - 0.11 11.8 0.2 0.24 10.7 0.2 1.5 1 0 0 1 1 1 0 KaiC PduV-EutP PF10662.9 OAP54531.1 - 0.12 12.1 0.1 0.12 12.1 0.1 2.2 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 OAP54531.1 - 0.13 12.3 0.4 23 5.1 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_14 PF13173.6 OAP54531.1 - 0.16 12.0 0.0 13 5.8 0.0 2.9 2 0 0 2 2 2 0 AAA domain Fer4_7 PF12838.7 OAP54531.1 - 0.47 11.1 12.4 0.065 13.8 1.5 2.2 1 1 2 3 3 3 0 4Fe-4S dicluster domain NTPase_1 PF03266.15 OAP54531.1 - 1.6 8.6 3.6 19 5.1 0.2 2.9 3 0 0 3 3 3 0 NTPase Fer4_2 PF12797.7 OAP54531.1 - 2.1 8.6 9.5 0.33 11.2 1.0 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_17 PF13534.6 OAP54531.1 - 4.7 7.8 10.0 0.2 12.2 0.8 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_8 PF13183.6 OAP54531.1 - 7.5 7.1 11.0 1.2 9.6 1.7 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain SNF2_N PF00176.23 OAP54532.1 - 1.5e-55 188.3 0.0 2.7e-55 187.5 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.24 OAP54532.1 - 8.3e-24 83.3 4.8 4e-15 55.5 0.5 3.0 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain DUF4208 PF13907.6 OAP54532.1 - 2.4e-20 72.8 1.1 9.5e-20 70.9 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4208) Helicase_C PF00271.31 OAP54532.1 - 2.3e-17 63.3 0.0 6.2e-17 61.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAP54532.1 - 2.6e-05 24.3 0.0 0.0014 18.7 0.0 2.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Cdh1_DBD_1 PF18196.1 OAP54532.1 - 5.7e-05 23.4 4.8 0.00013 22.2 1.2 4.8 4 1 1 5 5 5 2 Chromodomain helicase DNA-binding domain 1 SLIDE PF09111.10 OAP54532.1 - 0.11 12.5 0.0 0.11 12.5 0.0 3.7 4 0 0 4 4 4 0 SLIDE CHDCT2 PF08074.11 OAP54532.1 - 0.16 12.1 0.0 0.16 12.1 0.0 3.5 4 0 0 4 4 4 0 CHDCT2 (NUC038) domain LIM PF00412.22 OAP54533.1 - 2.3e-24 85.3 21.6 1.4e-09 38.0 5.1 3.6 3 0 0 3 3 3 3 LIM domain DUF2321 PF10083.9 OAP54533.1 - 0.0082 15.8 1.6 0.0082 15.8 1.6 3.3 2 1 1 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2321) Zn_ribbon_recom PF13408.6 OAP54533.1 - 0.011 16.2 2.7 0.011 16.2 2.7 2.7 3 0 0 3 3 3 0 Recombinase zinc beta ribbon domain DZR PF12773.7 OAP54533.1 - 0.019 15.0 6.7 0.019 15.0 6.7 4.0 2 1 1 4 4 4 0 Double zinc ribbon Paired_CXXCH_1 PF09699.10 OAP54533.1 - 0.21 11.4 8.7 0.06 13.1 0.8 2.9 2 0 0 2 2 2 0 Doubled CXXCH motif (Paired_CXXCH_1) MFS_1 PF07690.16 OAP54534.1 - 4.5e-25 88.3 38.9 7.3e-25 87.6 38.9 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 OAP54534.1 - 0.0014 17.6 0.1 0.0014 17.6 0.1 2.1 2 0 0 2 2 2 1 MFS_1 like family MFS_2 PF13347.6 OAP54534.1 - 0.0034 16.0 6.4 0.0034 16.0 6.4 2.6 1 1 2 3 3 3 1 MFS/sugar transport protein DUF2518 PF10726.9 OAP54534.1 - 3.5 7.3 5.2 16 5.1 0.1 2.6 2 0 0 2 2 2 0 Protein of function (DUF2518) HET PF06985.11 OAP54535.1 - 4.6e-08 33.5 0.0 2.4e-05 24.7 0.0 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Abhydrolase_6 PF12697.7 OAP54535.1 - 0.078 13.6 0.3 0.078 13.6 0.3 2.5 2 0 0 2 2 2 0 Alpha/beta hydrolase family Glyco_transf_90 PF05686.12 OAP54536.1 - 9.4e-36 123.6 0.7 1.7e-35 122.7 0.7 1.3 1 1 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.6 OAP54536.1 - 0.023 15.1 0.1 0.06 13.7 0.1 1.7 1 1 0 1 1 1 0 Glycosyl transferases group 1 PQ-loop PF04193.14 OAP54537.1 - 6.5e-09 35.4 13.6 4.9e-05 23.0 0.3 3.0 3 0 0 3 3 3 2 PQ loop repeat TMEM51 PF15345.6 OAP54537.1 - 0.00021 21.2 0.0 0.00033 20.6 0.0 1.3 1 0 0 1 1 1 1 Transmembrane protein 51 SUR7 PF06687.12 OAP54537.1 - 0.073 12.7 0.1 0.073 12.7 0.1 3.0 2 1 1 3 3 3 0 SUR7/PalI family EphA2_TM PF14575.6 OAP54537.1 - 0.13 13.2 1.0 1.2 10.1 0.0 2.8 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Phage_holin_2_3 PF16080.5 OAP54537.1 - 0.16 11.8 3.1 1.3 8.9 0.1 2.8 2 0 0 2 2 2 0 Bacteriophage holin family HP1 SurE PF01975.17 OAP54539.1 - 1.6e-33 116.1 0.0 2.3e-33 115.7 0.0 1.1 1 0 0 1 1 1 1 Survival protein SurE Transp_cyt_pur PF02133.15 OAP54540.1 - 1.7e-95 320.4 35.9 2e-95 320.2 35.9 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Polysacc_deac_1 PF01522.21 OAP54541.1 - 8.5e-12 45.1 0.0 1.5e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase NARP1 PF12569.8 OAP54542.1 - 7e-198 658.7 18.9 1.6e-196 654.2 9.0 2.4 1 1 0 2 2 2 2 NMDA receptor-regulated protein 1 TPR_19 PF14559.6 OAP54542.1 - 1.2e-22 80.1 20.4 1.8e-05 25.1 3.6 6.6 6 0 0 6 6 6 5 Tetratricopeptide repeat Fungal_trans PF04082.18 OAP54542.1 - 9.7e-22 77.3 1.2 5.7e-21 74.7 1.2 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain TPR_16 PF13432.6 OAP54542.1 - 1.3e-17 64.1 12.7 0.0026 18.4 4.0 7.8 4 1 4 8 8 8 6 Tetratricopeptide repeat TPR_14 PF13428.6 OAP54542.1 - 1.8e-16 59.4 14.0 0.03 15.1 1.6 9.8 7 3 4 11 11 8 4 Tetratricopeptide repeat TPR_2 PF07719.17 OAP54542.1 - 2.7e-14 52.0 32.2 0.00061 19.7 0.1 10.8 11 0 0 11 11 10 3 Tetratricopeptide repeat TPR_9 PF13371.6 OAP54542.1 - 2.8e-08 33.8 6.4 0.0035 17.4 0.2 6.1 5 2 1 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 OAP54542.1 - 6.1e-08 32.2 27.2 2.4e-05 24.0 0.1 7.8 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_8 PF13181.6 OAP54542.1 - 4.9e-07 29.5 23.4 0.00072 19.6 0.1 7.0 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 OAP54542.1 - 1.7e-06 28.2 23.0 0.014 15.7 0.3 7.1 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_17 PF13431.6 OAP54542.1 - 2.2e-06 27.7 14.7 0.0075 16.6 0.0 8.1 10 0 0 10 10 9 1 Tetratricopeptide repeat TPR_11 PF13414.6 OAP54542.1 - 2.6e-06 27.0 6.1 4.3e-05 23.1 0.0 4.3 4 0 0 4 4 3 1 TPR repeat ANAPC3 PF12895.7 OAP54542.1 - 2.7e-06 27.5 23.1 4.5e-05 23.6 1.3 5.2 4 1 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 OAP54542.1 - 3.4e-05 23.2 11.6 0.013 14.8 0.2 3.7 2 1 1 3 3 3 2 Tetratricopeptide repeat DUF2730 PF10805.8 OAP54542.1 - 0.00036 20.6 0.6 11 6.1 0.0 5.0 5 0 0 5 5 5 0 Protein of unknown function (DUF2730) TPR_6 PF13174.6 OAP54542.1 - 0.001 19.5 21.0 9.5 7.1 0.2 9.1 10 0 0 10 10 8 0 Tetratricopeptide repeat TPR_3 PF07720.12 OAP54542.1 - 0.024 14.6 1.7 4.6 7.3 0.2 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Patatin PF01734.22 OAP54542.1 - 0.14 12.3 0.2 2.6 8.2 0.1 2.4 2 0 0 2 2 2 0 Patatin-like phospholipase Fis1_TPR_C PF14853.6 OAP54542.1 - 0.14 12.2 9.3 13 5.9 0.1 5.2 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat TPR_4 PF07721.14 OAP54542.1 - 0.5 11.1 12.3 1 10.2 0.1 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 OAP54542.1 - 1.2 9.3 18.2 23 5.3 0.0 7.1 8 0 0 8 8 7 0 Tetratricopeptide repeat Fungal_trans PF04082.18 OAP54543.1 - 1.6e-17 63.4 0.0 2.5e-17 62.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP54543.1 - 1.1e-08 35.1 9.2 1.7e-08 34.4 9.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.24 OAP54544.1 - 7.4e-81 272.3 24.3 8.5e-81 272.1 24.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP54544.1 - 7.1e-17 61.4 35.0 7.1e-17 61.4 35.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PSI_PSAK PF01241.18 OAP54544.1 - 0.051 13.6 2.5 0.072 13.1 0.7 2.3 2 0 0 2 2 2 0 Photosystem I psaG / psaK FAD_binding_3 PF01494.19 OAP54545.1 - 6.5e-20 71.7 0.6 4.9e-19 68.8 0.6 2.0 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 OAP54545.1 - 1.6e-07 30.8 1.2 0.014 14.7 0.2 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAP54545.1 - 2.6e-07 30.6 9.0 0.00014 21.6 0.1 2.3 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 OAP54545.1 - 5.6e-05 23.6 2.3 0.046 14.3 0.3 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAP54545.1 - 7.6e-05 22.9 1.2 0.00016 21.8 1.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 OAP54545.1 - 0.0001 21.8 0.2 0.00018 21.0 0.2 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 OAP54545.1 - 0.00035 19.6 3.0 0.15 10.9 0.0 2.8 2 1 1 3 3 3 2 Tryptophan halogenase FAD_binding_2 PF00890.24 OAP54545.1 - 0.00082 18.6 5.5 0.0016 17.6 5.5 1.4 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 OAP54545.1 - 0.00093 18.3 3.7 0.0088 15.1 3.7 2.0 1 1 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.14 OAP54545.1 - 0.0017 17.1 2.6 0.11 11.2 2.2 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 OAP54545.1 - 0.0091 15.3 2.5 0.2 10.9 2.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OAP54545.1 - 0.034 13.3 4.1 0.062 12.4 4.1 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A SE PF08491.10 OAP54545.1 - 0.19 10.7 0.0 0.34 9.9 0.0 1.3 1 0 0 1 1 1 0 Squalene epoxidase Thi4 PF01946.17 OAP54545.1 - 0.19 10.9 0.5 0.34 10.1 0.5 1.3 1 0 0 1 1 1 0 Thi4 family Amino_oxidase PF01593.24 OAP54545.1 - 0.35 10.1 3.4 2.2 7.5 1.2 2.3 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.19 OAP54546.1 - 3.9e-24 85.5 0.3 2.6e-15 56.5 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 OAP54546.1 - 1.5e-10 41.2 9.4 2.9e-05 23.8 0.0 2.3 1 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAP54546.1 - 5.9e-10 38.8 4.9 4e-05 23.0 2.6 2.2 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAP54546.1 - 9.9e-08 32.4 1.0 0.00014 22.3 0.8 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAP54546.1 - 2.9e-07 29.9 5.7 4.8e-07 29.2 5.7 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 OAP54546.1 - 1.1e-05 25.0 0.4 1.4e-05 24.6 0.4 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 OAP54546.1 - 1.1e-05 24.6 3.2 2.8e-05 23.4 3.2 1.6 1 1 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.14 OAP54546.1 - 1.4e-05 24.0 3.3 0.00049 18.9 2.3 2.0 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.6 OAP54546.1 - 4.6e-05 23.6 2.5 0.00013 22.2 2.5 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 OAP54546.1 - 0.00041 19.7 3.8 0.02 14.2 0.8 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase GIDA PF01134.22 OAP54546.1 - 0.0012 18.0 5.3 0.0035 16.5 5.3 1.8 1 1 0 1 1 1 1 Glucose inhibited division protein A Trp_halogenase PF04820.14 OAP54546.1 - 0.0036 16.2 6.3 0.17 10.7 4.2 2.2 1 1 0 2 2 2 2 Tryptophan halogenase Thi4 PF01946.17 OAP54546.1 - 0.0047 16.2 1.0 0.0047 16.2 1.0 1.6 2 0 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.6 OAP54546.1 - 0.027 13.7 3.1 0.041 13.1 3.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 OAP54546.1 - 0.047 13.0 3.5 0.049 12.9 1.8 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Rossmann-like PF10727.9 OAP54546.1 - 0.2 11.5 2.8 0.73 9.7 1.6 2.3 2 0 0 2 2 2 0 Rossmann-like domain HgmA PF04209.13 OAP54547.1 - 1.2e-135 452.5 0.0 1.5e-135 452.2 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase SesA PF17107.5 OAP54548.1 - 4.8e-27 94.6 0.0 9.6e-27 93.6 0.0 1.5 2 0 0 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF4456 PF14644.6 OAP54548.1 - 0.002 17.8 0.0 0.0031 17.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4456) Beta-lactamase PF00144.24 OAP54551.1 - 6.2e-56 190.0 0.0 8.1e-56 189.6 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.8 OAP54551.1 - 1.3e-07 32.0 0.1 2.4e-07 31.1 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) NB-ARC PF00931.22 OAP54552.1 - 8.6e-14 51.3 0.0 3.8e-12 45.9 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain TPR_12 PF13424.6 OAP54552.1 - 1.6e-11 44.4 7.8 7.3e-09 35.8 0.1 4.7 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 OAP54552.1 - 2.3e-06 27.2 0.5 0.00064 19.4 0.0 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 OAP54552.1 - 3.4e-06 26.7 3.6 0.02 15.0 0.0 5.9 6 0 0 6 6 6 1 Tetratricopeptide repeat AAA_16 PF13191.6 OAP54552.1 - 4e-06 27.3 0.0 1.5e-05 25.4 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain TPR_8 PF13181.6 OAP54552.1 - 3.8e-05 23.6 1.3 0.11 12.8 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 OAP54552.1 - 0.00093 19.1 0.1 0.032 14.3 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 OAP54552.1 - 0.003 17.4 0.7 5.9 6.9 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 OAP54552.1 - 0.0067 16.6 0.3 0.43 10.8 0.1 3.7 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 OAP54552.1 - 0.02 15.5 0.1 0.26 12.0 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat AAA_22 PF13401.6 OAP54552.1 - 0.047 14.0 0.0 0.15 12.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain TPR_14 PF13428.6 OAP54552.1 - 0.16 12.9 8.3 23 6.2 0.0 5.9 7 1 1 8 8 5 0 Tetratricopeptide repeat Yop-YscD_cpl PF16697.5 OAP54554.1 - 0.15 12.3 0.1 0.24 11.8 0.1 1.2 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain Aspzincin_M35 PF14521.6 OAP54555.1 - 0.2 12.2 1.3 0.62 10.6 0.1 2.4 2 1 1 3 3 3 0 Lysine-specific metallo-endopeptidase HNH_2 PF13391.6 OAP54559.1 - 0.018 15.2 0.0 0.037 14.2 0.0 1.5 1 0 0 1 1 1 0 HNH endonuclease HNH PF01844.23 OAP54559.1 - 0.1 12.8 0.1 0.24 11.6 0.1 1.6 1 0 0 1 1 1 0 HNH endonuclease Flavi_NS4B PF01349.17 OAP54559.1 - 0.15 11.4 0.0 0.21 10.9 0.0 1.1 1 0 0 1 1 1 0 Flavivirus non-structural protein NS4B TPR_12 PF13424.6 OAP54561.1 - 1.7e-28 98.7 3.3 2.1e-11 44.0 0.1 2.8 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.6 OAP54561.1 - 7.8e-26 89.2 4.0 1.5e-09 37.4 0.0 3.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 OAP54561.1 - 3.6e-07 29.8 1.1 0.048 13.7 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 OAP54561.1 - 1.3e-05 25.7 0.2 0.44 11.2 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_4 PF07721.14 OAP54561.1 - 1.5e-05 25.1 0.2 0.045 14.4 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 OAP54561.1 - 3.3e-05 23.7 0.0 0.88 9.8 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 OAP54561.1 - 4e-05 24.1 0.8 0.41 11.6 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 OAP54561.1 - 6.4e-05 22.6 0.0 4.2 7.4 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 OAP54561.1 - 0.0002 21.5 0.0 0.84 10.2 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat PPR PF01535.20 OAP54561.1 - 0.00055 20.0 0.0 5.5 7.5 0.0 3.2 3 0 0 3 3 3 2 PPR repeat TPR_8 PF13181.6 OAP54561.1 - 0.002 18.2 0.0 1.5 9.2 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 OAP54561.1 - 0.052 14.0 0.1 1.4 9.4 0.0 2.4 1 1 2 3 3 3 0 Tetratricopeptide repeat DUF4404 PF14357.6 OAP54561.1 - 0.075 13.7 0.1 0.53 10.9 0.0 2.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4404) CysG_dimeriser PF10414.9 OAP54561.1 - 0.18 11.6 2.2 0.57 9.9 0.1 2.5 3 0 0 3 3 3 0 Sirohaem synthase dimerisation region Matrilin_ccoil PF10393.9 OAP54562.1 - 0.0012 18.6 1.9 0.0029 17.4 0.3 2.1 1 1 1 2 2 2 1 Trimeric coiled-coil oligomerisation domain of matrilin Helo_like_N PF17111.5 OAP54562.1 - 0.0036 16.7 0.1 0.0038 16.6 0.1 1.0 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins Lebercilin PF15619.6 OAP54562.1 - 0.0066 16.1 1.0 0.0083 15.8 1.0 1.2 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease DUF2838 PF10998.8 OAP54563.1 - 0.065 13.5 0.8 0.27 11.5 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2838) Ribonuc_red_lgC PF02867.15 OAP54565.1 - 1.6e-13 50.0 0.0 2e-13 49.7 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain DUF2007 PF09413.10 OAP54567.1 - 0.014 15.5 0.0 0.022 14.9 0.0 1.3 1 0 0 1 1 1 0 Putative prokaryotic signal transducing protein DUF1631 PF07793.11 OAP54570.1 - 0.054 11.9 0.1 0.1 11.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) DUF4470 PF14737.6 OAP54571.1 - 9.8e-26 89.8 0.0 1.9e-25 88.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) zf-MYND PF01753.18 OAP54571.1 - 4.7e-11 42.6 12.2 9.5e-11 41.6 12.2 1.6 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 OAP54571.1 - 0.11 12.9 8.7 0.24 11.7 8.7 1.6 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding PAN_2 PF08276.11 OAP54572.1 - 0.26 11.4 4.7 0.54 10.4 1.0 3.1 2 0 0 2 2 2 0 PAN-like domain PAN_4 PF14295.6 OAP54572.1 - 1.1 9.2 8.5 0.76 9.7 4.4 2.4 2 0 0 2 2 2 0 PAN domain F-box PF00646.33 OAP54574.1 - 0.012 15.4 0.2 0.09 12.7 0.0 2.7 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.7 OAP54574.1 - 1.1 9.2 5.5 1.1 9.2 1.9 3.0 2 1 0 2 2 2 0 F-box-like SAF PF08666.12 OAP54578.1 - 2.8e-05 24.7 0.3 8.2e-05 23.2 0.0 2.0 2 0 0 2 2 2 1 SAF domain GFO_IDH_MocA PF01408.22 OAP54578.1 - 3.4e-05 24.6 0.1 0.0001 23.1 0.1 1.8 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 OAP54578.1 - 7.6e-05 23.4 0.0 0.00018 22.2 0.0 1.7 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Dabb PF07876.12 OAP54579.1 - 1.3e-16 61.0 0.0 1.5e-16 60.8 0.0 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain MFS_1 PF07690.16 OAP54580.1 - 1.3e-34 119.7 24.2 1.3e-34 119.7 24.2 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Aldedh PF00171.22 OAP54581.1 - 5.2e-173 575.8 0.1 5.8e-173 575.6 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 OAP54581.1 - 0.0034 16.5 0.0 0.0047 16.0 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) ABM PF03992.16 OAP54582.1 - 1.9e-11 43.9 0.0 2.2e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Cupin_2 PF07883.11 OAP54583.1 - 0.00018 21.2 0.0 0.00033 20.3 0.0 1.5 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 OAP54583.1 - 0.08 12.6 0.0 0.65 9.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF861) AraC_binding PF02311.19 OAP54583.1 - 0.11 12.4 0.1 0.2 11.6 0.1 1.3 1 0 0 1 1 1 0 AraC-like ligand binding domain FMN_dh PF01070.18 OAP54584.1 - 3.4e-124 414.4 0.0 4.2e-124 414.1 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 OAP54584.1 - 5e-23 81.0 0.0 1.1e-22 80.0 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 OAP54584.1 - 2e-08 33.8 0.0 3.3e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 OAP54584.1 - 7.8e-05 21.8 1.0 0.00019 20.6 0.2 2.0 2 1 1 3 3 3 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 OAP54584.1 - 0.00033 20.2 0.2 0.00057 19.4 0.2 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.21 OAP54584.1 - 0.025 14.1 2.0 0.38 10.2 0.1 2.5 2 1 0 3 3 3 0 Histidine biosynthesis protein ThiG PF05690.14 OAP54584.1 - 0.045 13.1 0.1 3.2 7.0 0.0 2.3 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG G3P_antiterm PF04309.12 OAP54584.1 - 0.05 13.0 0.0 9.1 5.7 0.0 2.5 2 1 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator Fungal_trans_2 PF11951.8 OAP54585.1 - 8.8e-14 51.1 0.0 1.2e-12 47.4 0.0 2.0 2 0 0 2 2 2 2 Fungal specific transcription factor domain Exo_endo_phos PF03372.23 OAP54587.1 - 6.2e-13 48.8 0.2 9.8e-13 48.2 0.2 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-GRF PF06839.12 OAP54587.1 - 0.00087 19.3 6.3 0.0026 17.8 6.3 1.8 1 1 0 1 1 1 1 GRF zinc finger Exo_endo_phos_2 PF14529.6 OAP54587.1 - 0.021 14.6 0.0 4.9 7.0 0.0 2.4 2 0 0 2 2 2 0 Endonuclease-reverse transcriptase SHR-BD PF06650.12 OAP54588.1 - 9.1e-98 326.9 0.0 1.4e-95 319.8 0.0 2.7 2 0 0 2 2 2 2 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13_mid_rpt PF16910.5 OAP54588.1 - 4.1e-96 321.0 9.3 6.3e-91 304.0 1.7 5.7 5 0 0 5 5 5 2 Repeating coiled region of VPS13 VPS13 PF16908.5 OAP54588.1 - 3e-79 266.2 1.5 2e-78 263.5 0.0 3.0 4 0 0 4 4 4 1 Vacuolar sorting-associated protein 13, N-terminal VPS13_C PF16909.5 OAP54588.1 - 3.1e-74 248.6 4.0 4.2e-70 235.1 0.4 2.9 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal Chorein_N PF12624.7 OAP54588.1 - 5.4e-41 139.3 0.1 5.4e-41 139.3 0.1 2.3 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 OAP54588.1 - 1.3e-06 28.6 0.2 1.1e-05 25.7 0.0 2.6 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain DUF896 PF05979.12 OAP54588.1 - 5.3 7.0 13.7 1.9 8.4 0.2 3.7 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF896) GAS PF13851.6 OAP54589.1 - 0.00043 19.7 11.1 0.00043 19.7 11.1 1.5 2 0 0 2 2 2 1 Growth-arrest specific micro-tubule binding Peptidase_S64 PF08192.11 OAP54589.1 - 0.019 13.5 1.5 0.021 13.4 1.5 1.2 1 0 0 1 1 1 0 Peptidase family S64 Atg14 PF10186.9 OAP54589.1 - 0.021 13.9 6.6 0.034 13.2 6.6 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Miff PF05644.11 OAP54589.1 - 0.11 12.1 8.5 0.0086 15.7 3.4 1.7 2 0 0 2 2 2 0 Mitochondrial and peroxisomal fission factor Mff DUF1664 PF07889.12 OAP54589.1 - 0.12 12.4 4.6 0.25 11.4 4.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) TMCO5 PF14992.6 OAP54589.1 - 0.21 11.1 7.5 0.36 10.4 7.5 1.3 1 0 0 1 1 1 0 TMCO5 family YabA PF06156.13 OAP54589.1 - 0.28 11.9 5.4 0.7 10.6 5.4 1.7 1 0 0 1 1 1 0 Initiation control protein YabA FUSC PF04632.12 OAP54589.1 - 0.55 8.7 11.0 0.92 8.0 11.0 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family BDV_P24 PF06595.11 OAP54589.1 - 2.4 8.0 7.4 2 8.3 1.1 2.3 2 0 0 2 2 2 0 Borna disease virus P24 protein AA_permease PF00324.21 OAP54590.1 - 2.9e-104 349.3 44.0 3.6e-104 349.0 44.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAP54590.1 - 7.7e-29 100.8 48.8 8.8e-29 100.6 48.8 1.0 1 0 0 1 1 1 1 Amino acid permease Matrilin_ccoil PF10393.9 OAP54591.1 - 0.00045 20.0 3.9 0.42 10.5 2.0 3.9 1 1 2 3 3 3 2 Trimeric coiled-coil oligomerisation domain of matrilin Baculo_PEP_C PF04513.12 OAP54591.1 - 0.0005 20.1 6.4 0.0013 18.7 6.4 1.7 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4795 PF16043.5 OAP54591.1 - 0.00081 19.0 0.3 0.0013 18.4 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4795) RPW8 PF05659.11 OAP54591.1 - 0.003 17.3 0.5 0.005 16.5 0.5 1.4 1 0 0 1 1 1 1 Arabidopsis broad-spectrum mildew resistance protein RPW8 Snapin_Pallidin PF14712.6 OAP54591.1 - 0.0042 17.5 3.1 0.024 15.0 3.1 2.1 1 1 0 1 1 1 1 Snapin/Pallidin HSBP1 PF06825.12 OAP54591.1 - 0.0042 16.9 7.6 3.1 7.7 7.5 3.4 1 1 0 1 1 1 1 Heat shock factor binding protein 1 APG17 PF04108.12 OAP54591.1 - 0.0043 16.2 0.2 0.0071 15.5 0.2 1.4 1 0 0 1 1 1 1 Autophagy protein Apg17 Sec34 PF04136.15 OAP54591.1 - 0.006 16.5 1.5 0.011 15.7 1.5 1.4 1 0 0 1 1 1 1 Sec34-like family CLZ PF16526.5 OAP54591.1 - 0.0061 16.9 3.5 2.2 8.7 3.5 3.0 1 1 0 1 1 1 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels BLOC1_2 PF10046.9 OAP54591.1 - 0.0071 16.6 1.1 0.037 14.3 1.0 2.3 1 1 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fzo_mitofusin PF04799.13 OAP54591.1 - 0.0072 15.9 0.2 0.0095 15.5 0.2 1.4 1 0 0 1 1 1 1 fzo-like conserved region TelA PF05816.11 OAP54591.1 - 0.01 15.0 0.1 0.013 14.6 0.1 1.2 1 0 0 1 1 1 0 Toxic anion resistance protein (TelA) Exonuc_VII_L PF02601.15 OAP54591.1 - 0.011 15.4 0.0 0.011 15.4 0.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Fer4_24 PF18109.1 OAP54591.1 - 0.013 15.8 4.1 0.65 10.3 0.3 3.3 2 1 1 3 3 3 0 Ferredoxin I 4Fe-4S cluster domain Allexi_40kDa PF05549.11 OAP54591.1 - 0.013 15.0 0.8 0.018 14.6 0.8 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein ALIX_LYPXL_bnd PF13949.6 OAP54591.1 - 0.014 14.7 0.7 0.022 14.1 0.6 1.3 1 1 0 1 1 1 0 ALIX V-shaped domain binding to HIV T3SSipB PF16535.5 OAP54591.1 - 0.015 15.8 0.8 0.039 14.4 0.8 1.6 1 1 0 1 1 1 0 Type III cell invasion protein SipB Dynamitin PF04912.14 OAP54591.1 - 0.03 13.7 0.4 0.044 13.1 0.4 1.3 1 0 0 1 1 1 0 Dynamitin NPV_P10 PF05531.12 OAP54591.1 - 0.03 14.8 6.1 0.19 12.2 3.6 2.7 2 1 0 2 2 1 0 Nucleopolyhedrovirus P10 protein Hemagglutinin PF00509.18 OAP54591.1 - 0.032 12.7 1.4 0.042 12.2 1.4 1.1 1 0 0 1 1 1 0 Haemagglutinin Tropomyosin PF00261.20 OAP54591.1 - 0.034 13.5 0.2 0.059 12.7 0.2 1.3 1 0 0 1 1 1 0 Tropomyosin COG2 PF06148.11 OAP54591.1 - 0.036 14.2 0.3 0.064 13.3 0.3 1.5 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF2408 PF10303.9 OAP54591.1 - 0.037 14.6 0.3 0.059 13.9 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) DUF1664 PF07889.12 OAP54591.1 - 0.038 14.0 2.5 0.14 12.2 2.5 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) EzrA PF06160.12 OAP54591.1 - 0.044 12.0 0.0 0.067 11.4 0.0 1.3 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA DUF16 PF01519.16 OAP54591.1 - 0.049 14.1 0.0 0.11 13.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function DUF16 PHM7_cyt PF14703.6 OAP54591.1 - 0.068 13.4 0.0 0.1 12.8 0.0 1.2 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter XhlA PF10779.9 OAP54591.1 - 0.11 12.7 3.5 0.21 11.8 2.2 2.2 1 1 1 2 2 2 0 Haemolysin XhlA DUF948 PF06103.11 OAP54591.1 - 0.11 12.7 2.2 0.39 11.0 2.2 2.0 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Spc7 PF08317.11 OAP54591.1 - 0.15 10.9 1.3 0.2 10.5 1.3 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Laminin_II PF06009.12 OAP54591.1 - 0.18 11.8 2.5 0.32 11.0 2.5 1.4 1 0 0 1 1 1 0 Laminin Domain II BORCS6 PF10157.9 OAP54591.1 - 0.22 11.7 3.9 0.28 11.4 2.7 1.6 1 1 1 2 2 1 0 BLOC-1-related complex sub-unit 6 Cep57_CLD_2 PF14197.6 OAP54591.1 - 0.66 10.1 4.7 4.4 7.5 3.2 2.8 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 TMF_DNA_bd PF12329.8 OAP54591.1 - 3.4 7.8 6.7 3.4 7.7 2.6 2.7 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DASH_Dam1 PF08653.10 OAP54591.1 - 7.8 6.4 6.6 5.8 6.8 1.4 2.8 1 1 2 3 3 3 0 DASH complex subunit Dam1 UPF0184 PF03670.13 OAP54591.1 - 9.4 6.7 9.7 17 5.9 0.3 2.8 2 1 1 3 3 2 0 Uncharacterised protein family (UPF0184) DUF1907 PF08925.11 OAP54592.1 - 6.3e-91 304.7 0.0 1.2e-90 303.9 0.0 1.4 1 1 0 1 1 1 1 Domain of Unknown Function (DUF1907) PNP_UDP_1 PF01048.20 OAP54595.1 - 2.1e-08 33.8 1.2 5.1e-08 32.5 1.2 1.7 1 1 0 1 1 1 1 Phosphorylase superfamily Ank_2 PF12796.7 OAP54596.1 - 6.6e-57 190.1 13.8 3.2e-12 46.9 0.0 5.4 2 1 5 7 7 7 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAP54596.1 - 9.6e-37 124.9 3.6 3.9e-06 27.3 0.0 8.1 1 1 7 8 8 8 8 Ankyrin repeats (many copies) Ank PF00023.30 OAP54596.1 - 9.2e-30 101.8 2.6 8.5e-05 22.8 0.0 8.2 8 0 0 8 8 8 7 Ankyrin repeat Ank_3 PF13606.6 OAP54596.1 - 2.2e-27 92.1 0.0 0.00071 19.9 0.0 7.8 7 0 0 7 7 7 7 Ankyrin repeat Ank_5 PF13857.6 OAP54596.1 - 1.1e-22 79.7 0.9 0.00058 20.1 0.0 6.9 1 1 6 7 7 7 6 Ankyrin repeats (many copies) HEM4 PF02602.15 OAP54596.1 - 0.03 13.7 1.0 27 4.0 0.1 4.1 1 1 2 4 4 4 0 Uroporphyrinogen-III synthase HemD GLTP PF08718.11 OAP54596.1 - 0.13 12.5 0.0 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 Glycolipid transfer protein (GLTP) Anoctamin PF04547.12 OAP54598.1 - 0.2 10.5 0.1 0.29 9.9 0.1 1.1 1 0 0 1 1 1 0 Calcium-activated chloride channel Abhydrolase_3 PF07859.13 OAP54599.1 - 2.4e-22 79.8 0.0 3.9e-22 79.1 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAP54599.1 - 0.0029 18.2 1.6 0.0041 17.8 0.8 1.7 1 1 1 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAP54599.1 - 0.091 12.0 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Ras PF00071.22 OAP54600.1 - 5.8e-12 45.5 0.0 1.2e-11 44.5 0.0 1.5 1 1 0 1 1 1 1 Ras family Roc PF08477.13 OAP54600.1 - 0.0054 17.0 0.0 0.012 15.8 0.0 1.8 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_18 PF13238.6 OAP54600.1 - 0.01 16.4 0.0 0.018 15.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 OAP54600.1 - 0.033 13.4 0.0 0.037 13.2 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain DUF3102 PF11300.8 OAP54600.1 - 0.04 14.2 0.1 0.067 13.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3102) AAA_16 PF13191.6 OAP54600.1 - 0.041 14.3 0.0 0.065 13.6 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain ATPase PF06745.13 OAP54600.1 - 0.048 13.0 0.1 0.062 12.6 0.1 1.3 1 1 0 1 1 1 0 KaiC cobW PF02492.19 OAP54600.1 - 0.057 13.0 0.0 0.083 12.5 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 OAP54600.1 - 0.065 13.5 0.0 0.088 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 OAP54600.1 - 0.09 12.1 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin MMR_HSR1 PF01926.23 OAP54600.1 - 0.092 12.8 0.0 0.31 11.1 0.0 1.9 1 1 1 2 2 2 0 50S ribosome-binding GTPase ABC_tran PF00005.27 OAP54600.1 - 0.11 13.1 0.0 0.19 12.2 0.0 1.3 1 1 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 OAP54600.1 - 0.13 12.0 0.1 0.21 11.3 0.1 1.3 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 OAP54600.1 - 0.14 11.1 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ATPase_2 PF01637.18 OAP54600.1 - 0.25 11.2 0.9 2.7 7.8 0.1 2.0 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea p450 PF00067.22 OAP54601.1 - 3.8e-45 154.5 0.0 4.8e-45 154.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 TMEM51 PF15345.6 OAP54602.1 - 0.097 12.5 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 FCH PF00611.23 OAP54603.1 - 5.3e-23 81.1 3.5 5.9e-23 81.0 0.2 2.6 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.6 OAP54603.1 - 3e-22 78.2 0.2 2.6e-11 43.2 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 OAP54603.1 - 2.2e-17 62.4 0.1 1.2e-08 34.4 0.0 2.4 2 0 0 2 2 2 2 SH3 domain C1_1 PF00130.22 OAP54603.1 - 3.2e-14 52.5 6.1 5.1e-14 51.9 6.1 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 OAP54603.1 - 0.0025 18.1 5.3 0.0044 17.3 5.3 1.4 1 0 0 1 1 1 1 C1 domain SH3_2 PF07653.17 OAP54603.1 - 0.011 15.4 0.0 0.046 13.4 0.0 2.0 2 0 0 2 2 2 0 Variant SH3 domain SH3_3 PF08239.11 OAP54603.1 - 0.02 15.2 0.0 0.9 9.9 0.0 2.6 2 0 0 2 2 2 0 Bacterial SH3 domain SH3_10 PF17902.1 OAP54603.1 - 0.039 14.0 0.0 1.4 9.0 0.0 2.7 2 0 0 2 2 2 0 SH3 domain Pyr_excise PF03013.14 OAP54603.1 - 0.17 11.9 5.7 0.35 10.9 1.6 2.5 2 0 0 2 2 2 0 Pyrimidine dimer DNA glycosylase OrfB_Zn_ribbon PF07282.11 OAP54603.1 - 0.24 11.4 2.0 0.79 9.7 2.0 1.9 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Ribosomal_L36e PF01158.18 OAP54603.1 - 0.67 10.2 3.8 0.24 11.7 0.3 2.1 2 0 0 2 2 2 0 Ribosomal protein L36e DEAD PF00270.29 OAP54604.1 - 1.4e-34 119.4 0.7 4.3e-34 117.8 0.1 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAP54604.1 - 3e-23 82.3 0.1 1.1e-22 80.5 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 OAP54604.1 - 0.044 13.5 0.0 0.087 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain CMS1 PF14617.6 OAP54604.1 - 0.075 12.4 0.0 0.18 11.1 0.0 1.6 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit AAA_22 PF13401.6 OAP54604.1 - 0.13 12.5 0.6 0.78 10.0 0.6 2.3 1 1 0 1 1 1 0 AAA domain Tachykinin PF02202.16 OAP54604.1 - 0.56 10.2 2.6 25 5.1 0.3 2.9 2 0 0 2 2 2 0 Tachykinin family GAF_2 PF13185.6 OAP54605.1 - 1.8e-11 44.5 0.1 2.6e-11 43.9 0.1 1.4 1 1 0 1 1 1 1 GAF domain GAF_3 PF13492.6 OAP54605.1 - 0.002 18.5 0.0 0.0058 17.0 0.0 1.7 2 0 0 2 2 2 1 GAF domain Metallophos PF00149.28 OAP54607.1 - 0.00069 20.2 0.0 0.004 17.7 0.0 2.0 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase DLH PF01738.18 OAP54608.1 - 2.9e-10 40.1 5.0 2e-09 37.3 5.0 2.2 1 1 0 1 1 1 1 Dienelactone hydrolase family Tcp11 PF05794.13 OAP54609.1 - 3.5e-76 257.1 2.6 3.5e-76 257.1 2.6 2.9 3 0 0 3 3 3 1 T-complex protein 11 IQ PF00612.27 OAP54609.1 - 0.019 14.7 1.9 0.052 13.4 1.9 1.8 1 0 0 1 1 1 0 IQ calmodulin-binding motif adh_short PF00106.25 OAP54610.1 - 2.5e-20 72.8 0.0 5e-15 55.5 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAP54610.1 - 1.2e-09 38.1 0.0 4.6e-09 36.2 0.0 1.8 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP54610.1 - 0.00033 20.6 0.0 0.00064 19.7 0.0 1.4 1 0 0 1 1 1 1 KR domain Cytochrom_B561 PF03188.16 OAP54612.1 - 3.7e-07 30.4 3.4 3.8e-05 23.8 7.7 2.2 3 0 0 3 3 3 1 Eukaryotic cytochrome b561 Cation_efflux PF01545.21 OAP54612.1 - 0.042 13.6 2.1 0.054 13.2 1.0 1.7 1 1 0 1 1 1 0 Cation efflux family DUF2057 PF09829.9 OAP54612.1 - 0.23 11.6 1.6 0.39 10.9 1.6 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) COX14 PF14880.6 OAP54612.1 - 0.51 10.2 1.6 1.3 8.9 0.0 2.6 2 0 0 2 2 2 0 Cytochrome oxidase c assembly DUF4418 PF14387.6 OAP54612.1 - 1.2 9.4 4.9 0.91 9.8 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4418) DUF4079 PF13301.6 OAP54612.1 - 5 7.3 13.9 13 5.9 2.4 3.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4079) PQ-loop PF04193.14 OAP54613.1 - 7.9e-34 115.2 9.3 4.1e-18 64.9 1.1 2.4 2 0 0 2 2 2 2 PQ loop repeat PalH PF08733.10 OAP54613.1 - 0.007 15.4 0.3 0.007 15.4 0.3 1.9 2 0 0 2 2 2 1 PalH/RIM21 DUF1761 PF08570.10 OAP54613.1 - 0.042 14.1 0.2 0.081 13.2 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1761) DUF3040 PF11239.8 OAP54613.1 - 0.54 10.6 2.1 1.8 8.9 0.6 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3040) zf-C2H2 PF00096.26 OAP54614.1 - 0.00055 20.2 2.6 0.00072 19.9 0.3 2.3 2 0 0 2 2 2 1 Zinc finger, C2H2 type Tim44 PF04280.15 OAP54616.1 - 0.04 14.0 0.2 0.56 10.3 0.0 2.2 2 0 0 2 2 2 0 Tim44-like domain UPF0139 PF03669.13 OAP54617.1 - 0.00035 20.4 0.0 0.00064 19.5 0.0 1.4 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0139) SUI1 PF01253.22 OAP54618.1 - 2.3e-28 98.5 3.3 2.9e-28 98.2 3.3 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 EOS1 PF12326.8 OAP54619.1 - 3.2e-10 40.2 6.8 3.2e-10 40.2 6.8 1.7 2 0 0 2 2 2 1 N-glycosylation protein HCO3_cotransp PF00955.21 OAP54620.1 - 7.7e-84 282.3 17.2 1.1e-44 153.2 8.3 2.1 1 1 1 2 2 2 2 HCO3- transporter family Pkinase PF00069.25 OAP54621.1 - 5.5e-17 62.0 0.1 1e-16 61.1 0.1 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP54621.1 - 3.4e-13 49.5 0.1 9.2e-13 48.1 0.1 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAP54621.1 - 0.031 13.6 0.0 0.1 11.9 0.0 1.8 1 1 0 1 1 1 0 Kinase-like GST_N PF02798.20 OAP54622.1 - 3.5e-11 43.3 0.0 5.8e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 OAP54622.1 - 1.1e-10 41.6 0.0 3.6e-10 39.9 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 OAP54622.1 - 3.9e-10 40.0 0.0 6.4e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OAP54622.1 - 1.4e-09 38.0 0.0 2.4e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 OAP54622.1 - 1.7e-08 34.6 0.0 3.3e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAP54622.1 - 1.2e-05 25.2 0.0 2.3e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Astro_capsid_p PF12226.8 OAP54623.1 - 0.32 10.1 14.6 0.02 14.0 9.3 1.7 2 0 0 2 2 2 0 Turkey astrovirus capsid protein DUF2076 PF09849.9 OAP54624.1 - 2.3e-07 31.2 13.3 2.9e-07 30.8 13.3 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.13 OAP54624.1 - 1.8e-05 24.8 3.9 2.5e-05 24.3 3.9 1.2 1 0 0 1 1 1 1 CHCH domain CX9C PF16860.5 OAP54624.1 - 0.016 15.2 1.0 0.027 14.5 1.0 1.3 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Trypan_glycop_C PF10659.9 OAP54624.1 - 0.047 14.1 0.5 0.083 13.3 0.5 1.4 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein C-terminal domain SF1-HH PF16275.5 OAP54625.1 - 3.2e-44 149.9 1.0 7.3e-44 148.7 1.0 1.6 1 0 0 1 1 1 1 Splicing factor 1 helix-hairpin domain zf-CCHC PF00098.23 OAP54625.1 - 5.5e-12 45.2 10.5 1.3e-05 25.0 0.8 2.6 2 0 0 2 2 2 2 Zinc knuckle KH_1 PF00013.29 OAP54625.1 - 1.6e-08 34.2 0.1 3e-08 33.4 0.1 1.5 1 0 0 1 1 1 1 KH domain zf-CCHC_3 PF13917.6 OAP54625.1 - 4.5e-05 23.3 4.0 0.096 12.7 1.8 2.6 1 1 1 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.6 OAP54625.1 - 0.0019 17.9 5.0 0.56 10.0 0.4 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_6 PF15288.6 OAP54625.1 - 0.0037 17.1 7.0 0.36 10.7 0.6 2.8 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.6 OAP54625.1 - 0.014 15.2 0.5 0.014 15.2 0.5 2.4 2 0 0 2 2 2 0 Zinc knuckle PHD_4 PF16866.5 OAP54625.1 - 0.51 10.5 2.2 1.2 9.3 2.2 1.6 1 0 0 1 1 1 0 PHD-finger Sulfotransfer_4 PF17784.1 OAP54626.1 - 1.7e-47 162.0 0.0 2e-47 161.8 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain adh_short PF00106.25 OAP54627.1 - 7.8e-16 58.1 0.0 2.6e-15 56.4 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 OAP54627.1 - 1.3e-06 28.5 0.1 1.9e-06 27.9 0.1 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 OAP54627.1 - 2.1e-06 27.5 0.0 2.8e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Ribosomal_L7Ae PF01248.26 OAP54628.1 - 1.9e-19 69.2 0.1 5.2e-19 67.8 0.1 1.8 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Cwf_Cwc_15 PF04889.12 OAP54628.1 - 0.13 12.0 30.1 0.071 12.8 22.2 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein DNA_pol_phi PF04931.13 OAP54628.1 - 2.1 6.3 18.8 0.016 13.3 8.5 2.2 2 0 0 2 2 2 0 DNA polymerase phi Zip PF02535.22 OAP54628.1 - 3.8 6.7 10.7 0.51 9.5 6.2 1.9 2 1 0 2 2 2 0 ZIP Zinc transporter CorA PF01544.18 OAP54629.1 - 7.9e-09 35.2 0.8 2.3e-08 33.7 0.8 1.9 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein SNARE_assoc PF09335.11 OAP54630.1 - 1.1e-14 55.0 4.8 1.1e-14 55.0 4.8 2.7 2 1 1 3 3 3 1 SNARE associated Golgi protein DUF2207 PF09972.9 OAP54630.1 - 0.21 10.3 1.2 0.41 9.4 1.2 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) MerE PF05052.12 OAP54630.1 - 1.3 9.0 5.9 0.87 9.6 3.6 1.9 2 0 0 2 2 2 0 MerE protein DUF2157 PF09925.9 OAP54630.1 - 1.7 8.4 7.6 0.33 10.7 2.9 2.1 2 1 0 2 2 2 0 Predicted membrane protein (DUF2157) PMP1_2 PF08114.11 OAP54630.1 - 6.6 6.6 6.4 0.76 9.6 0.1 2.6 3 0 0 3 3 3 0 ATPase proteolipid family DUF1771 PF08590.10 OAP54631.1 - 1.1e-14 54.5 14.2 2e-14 53.7 14.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) zf_CCCH_4 PF18345.1 OAP54631.1 - 1.2e-09 37.9 10.8 1.4e-06 28.1 3.0 2.9 2 1 0 2 2 2 2 Zinc finger domain zf-CCCH PF00642.24 OAP54631.1 - 4e-09 36.1 2.8 0.00073 19.4 0.4 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Smr PF01713.21 OAP54631.1 - 3.1e-08 33.9 0.0 9.7e-08 32.3 0.0 1.9 1 0 0 1 1 1 1 Smr domain zf-CCCH_2 PF14608.6 OAP54631.1 - 2.1e-06 28.0 5.5 0.0033 17.8 0.7 2.3 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger zf-CCCH_4 PF18044.1 OAP54631.1 - 3.5e-06 26.7 10.2 4.6e-05 23.1 1.0 3.1 2 1 0 2 2 2 2 CCCH-type zinc finger zf-CCCH_3 PF15663.5 OAP54631.1 - 0.0025 18.0 3.2 1.1 9.5 0.3 2.7 2 1 1 3 3 3 2 Zinc-finger containing family Torus PF16131.5 OAP54631.1 - 0.019 15.7 2.6 0.074 13.8 2.6 1.9 1 1 0 1 1 1 0 Torus domain zf-C3H1 PF10650.9 OAP54631.1 - 0.37 10.6 2.2 3 7.6 0.0 2.3 2 0 0 2 2 2 0 Putative zinc-finger domain TIM21 PF08294.11 OAP54632.1 - 1.4e-28 99.6 0.0 2e-28 99.1 0.0 1.2 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.10 OAP54632.1 - 0.0017 18.0 0.0 0.0059 16.3 0.0 1.8 1 1 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 RhoGAP PF00620.27 OAP54633.1 - 2.3e-37 128.2 0.0 3.5e-37 127.6 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain Hydrolase_6 PF13344.6 OAP54634.1 - 6.1e-23 80.8 0.0 1.3e-22 79.8 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OAP54634.1 - 7.5e-12 45.1 0.0 4.1e-11 42.8 0.0 2.3 1 1 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 OAP54634.1 - 0.0015 18.9 0.0 3.6 7.8 0.0 2.9 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Actino_peptide PF14408.6 OAP54634.1 - 0.055 13.6 1.2 0.15 12.2 1.2 1.8 1 0 0 1 1 1 0 Ribosomally synthesised peptide in actinomycetes Lipase_3 PF01764.25 OAP54634.1 - 0.12 12.3 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) DUF676 PF05057.14 OAP54635.1 - 4.5e-50 170.2 0.0 6.1e-50 169.8 0.0 1.1 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 OAP54635.1 - 1.4e-06 29.1 0.0 2.2e-06 28.4 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Palm_thioest PF02089.15 OAP54635.1 - 3.5e-05 23.7 0.0 5.5e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase PGAP1 PF07819.13 OAP54635.1 - 0.0016 18.2 0.0 0.0062 16.3 0.0 1.8 1 1 0 1 1 1 1 PGAP1-like protein Lipase_3 PF01764.25 OAP54635.1 - 0.0052 16.6 0.0 0.0087 15.9 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) DUF915 PF06028.11 OAP54635.1 - 0.042 13.2 0.0 0.11 11.8 0.0 1.6 1 1 1 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Hydrolase_4 PF12146.8 OAP54635.1 - 0.078 12.2 0.1 1.3 8.2 0.0 2.1 2 0 0 2 2 2 0 Serine aminopeptidase, S33 PE-PPE PF08237.11 OAP54635.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 PE-PPE domain Abhydrolase_2 PF02230.16 OAP54635.1 - 0.11 12.3 0.0 10 5.8 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase UPF0227 PF05728.12 OAP54635.1 - 0.11 12.4 0.2 0.86 9.5 0.1 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) Arf PF00025.21 OAP54637.1 - 6.8e-74 247.1 0.1 8e-74 246.8 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 OAP54637.1 - 4.7e-14 52.6 0.0 6.1e-14 52.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 OAP54637.1 - 1.6e-11 44.0 0.0 1.9e-11 43.8 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 OAP54637.1 - 2.2e-11 43.6 1.5 2.7e-07 30.1 0.2 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 OAP54637.1 - 3.3e-11 43.0 0.0 4e-11 42.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 OAP54637.1 - 1.4e-10 40.9 0.0 1.8e-10 40.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 OAP54637.1 - 0.0003 20.9 0.0 0.00051 20.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 OAP54637.1 - 0.029 13.7 0.2 0.05 12.9 0.1 1.4 2 0 0 2 2 2 0 6-phosphofructo-2-kinase Epimerase PF01370.21 OAP54638.1 - 1.1e-18 67.6 0.0 1.5e-18 67.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 OAP54638.1 - 4.8e-10 39.0 0.0 9.5e-10 38.0 0.0 1.5 2 0 0 2 2 2 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 OAP54638.1 - 4.8e-05 23.3 0.0 9.5e-05 22.4 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 OAP54638.1 - 6.6e-05 22.0 0.0 0.00026 20.1 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 OAP54638.1 - 0.00016 21.2 0.0 0.00067 19.2 0.0 1.9 1 1 1 2 2 2 1 short chain dehydrogenase GDP_Man_Dehyd PF16363.5 OAP54638.1 - 0.003 17.0 0.0 0.006 16.0 0.0 1.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase KR PF08659.10 OAP54638.1 - 0.052 13.5 0.0 0.083 12.8 0.0 1.3 1 0 0 1 1 1 0 KR domain adh_short_C2 PF13561.6 OAP54638.1 - 0.22 11.0 0.0 0.35 10.4 0.0 1.4 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Vezatin PF12632.7 OAP54640.1 - 3e-63 213.8 0.1 9.6e-63 212.2 0.0 1.8 2 0 0 2 2 2 1 Mysoin-binding motif of peroxisomes UPF0697 PF15117.6 OAP54640.1 - 0.02 15.0 0.0 0.047 13.8 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family UPF0697 PCNA_N PF00705.18 OAP54641.1 - 5.6e-54 181.2 4.8 9.6e-54 180.5 4.8 1.3 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 OAP54641.1 - 5.9e-52 175.2 0.5 3.7e-51 172.6 0.1 2.1 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.13 OAP54641.1 - 2.1e-08 34.0 0.5 2.8e-08 33.5 0.5 1.1 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.16 OAP54641.1 - 2.3e-08 33.4 2.2 4.1e-06 26.1 2.2 2.2 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Hus1 PF04005.12 OAP54641.1 - 0.00059 19.0 0.9 0.002 17.3 0.1 2.0 2 1 0 2 2 2 1 Hus1-like protein pPIWI_RE_Y PF18156.1 OAP54641.1 - 0.0056 17.1 0.3 0.11 12.9 0.2 2.4 2 0 0 2 2 2 1 pPIWI_RE three-gene island domain Y TPR_14 PF13428.6 OAP54641.1 - 1 10.4 11.1 51 5.1 0.1 4.7 3 1 1 4 4 4 0 Tetratricopeptide repeat Phos_pyr_kin PF08543.12 OAP54642.1 - 2.7e-12 46.6 0.0 5.1e-12 45.7 0.0 1.4 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 OAP54642.1 - 2.9e-06 26.8 0.1 3.2e-05 23.4 0.0 2.2 3 0 0 3 3 3 1 pfkB family carbohydrate kinase dUTPase PF00692.19 OAP54643.1 - 3.9e-46 155.9 0.0 4.9e-46 155.6 0.0 1.1 1 0 0 1 1 1 1 dUTPase APH PF01636.23 OAP54644.1 - 1.9e-42 145.8 0.0 2.7e-42 145.3 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 OAP54644.1 - 5.8e-05 22.6 0.0 9.3e-05 21.9 0.0 1.4 1 1 0 1 1 1 1 Ecdysteroid kinase Kdo PF06293.14 OAP54644.1 - 0.0004 19.8 0.0 0.0016 17.9 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1679 PF07914.11 OAP54644.1 - 0.00042 19.3 0.0 0.0035 16.3 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1679) RIO1 PF01163.22 OAP54644.1 - 0.0044 16.6 0.0 0.068 12.8 0.0 2.1 2 0 0 2 2 2 1 RIO1 family Fructosamin_kin PF03881.14 OAP54644.1 - 0.0044 16.3 0.0 0.11 11.6 0.0 2.2 1 1 0 1 1 1 1 Fructosamine kinase Choline_kinase PF01633.20 OAP54644.1 - 0.0049 16.5 0.0 0.0075 15.9 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase zf-C2H2 PF00096.26 OAP54645.1 - 0.00049 20.4 8.2 0.01 16.2 0.1 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAP54645.1 - 0.26 12.3 0.0 0.26 12.3 0.0 4.1 4 0 0 4 4 4 0 C2H2-type zinc finger Med27 PF11571.8 OAP54646.1 - 2.8e-09 37.2 0.0 5.6e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Mediator complex subunit 27 Thioredoxin_5 PF13743.6 OAP54646.1 - 0.098 12.3 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin GBP_PSP PF02425.15 OAP54647.1 - 0.31 10.7 0.7 2.1 8.1 0.1 2.4 2 0 0 2 2 2 0 Paralytic/GBP/PSP peptide SOG2 PF10428.9 OAP54648.1 - 0.054 12.7 3.5 0.061 12.5 3.5 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Menin PF05053.13 OAP54648.1 - 0.093 11.1 1.7 0.15 10.4 1.7 1.3 1 0 0 1 1 1 0 Menin Dicty_REP PF05086.12 OAP54649.1 - 2 6.3 5.3 2.2 6.2 5.3 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein TPR_1 PF00515.28 OAP54650.1 - 5.1e-13 48.2 8.2 2.9e-06 26.8 0.0 4.8 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 OAP54650.1 - 9.3e-13 47.2 4.3 0.00017 21.4 0.0 5.0 4 1 1 5 5 5 3 Tetratricopeptide repeat PB1 PF00564.24 OAP54650.1 - 3.6e-08 33.2 0.4 7.1e-08 32.3 0.4 1.5 1 0 0 1 1 1 1 PB1 domain TPR_12 PF13424.6 OAP54650.1 - 4e-07 30.2 0.1 0.0016 18.7 0.0 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 OAP54650.1 - 1.5e-06 27.9 1.0 0.0011 19.0 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 OAP54650.1 - 4.2e-06 26.4 0.5 0.00048 20.0 0.0 3.4 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 OAP54650.1 - 2.1e-05 24.1 2.2 0.00014 21.5 0.1 3.2 2 1 1 3 3 3 1 TPR repeat TPR_6 PF13174.6 OAP54650.1 - 4.5e-05 23.8 0.8 17 6.3 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 OAP54650.1 - 0.00088 19.9 0.1 0.037 14.7 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 OAP54650.1 - 0.0024 18.0 0.1 0.87 9.8 0.0 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 OAP54650.1 - 0.0097 16.2 1.1 0.37 11.3 0.0 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 OAP54650.1 - 0.029 15.2 0.1 2.9 9.0 0.0 3.0 3 0 0 3 3 2 0 Tetratricopeptide repeat Imm-NTF2 PF15655.6 OAP54650.1 - 0.074 13.3 0.1 0.21 11.9 0.1 1.7 1 0 0 1 1 1 0 NTF2 fold immunity protein TPR_10 PF13374.6 OAP54650.1 - 0.26 11.2 2.7 16 5.6 0.1 3.6 3 1 1 4 4 4 0 Tetratricopeptide repeat HMA PF00403.26 OAP54651.1 - 1.1e-11 45.0 0.0 2.1e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 Heavy-metal-associated domain Sod_Cu PF00080.20 OAP54651.1 - 1.5e-09 38.2 0.0 2.2e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) SET PF00856.28 OAP54652.1 - 4.4e-15 56.5 0.0 6.4e-15 55.9 0.0 1.3 1 0 0 1 1 1 1 SET domain Ish1 PF10281.9 OAP54652.1 - 0.076 13.3 0.0 0.24 11.7 0.0 1.9 1 0 0 1 1 1 0 Putative stress-responsive nuclear envelope protein Pkinase PF00069.25 OAP54653.1 - 9.4e-06 25.2 0.0 1.5e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Rrn6 PF10214.9 OAP54653.1 - 0.76 8.2 6.7 0.97 7.8 6.7 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Presenilin PF01080.17 OAP54653.1 - 2.1 7.0 3.5 2.2 6.9 3.5 1.1 1 0 0 1 1 1 0 Presenilin DUF4554 PF15091.6 OAP54653.1 - 3.6 6.4 5.6 4.7 6.0 5.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) Pkinase PF00069.25 OAP54654.1 - 1.8e-47 161.9 0.0 2.1e-47 161.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP54654.1 - 1.2e-18 67.4 0.0 1.5e-18 67.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OAP54654.1 - 0.00013 21.4 0.0 0.00017 21.0 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OAP54654.1 - 0.0064 15.8 0.1 0.014 14.8 0.1 1.6 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 OAP54654.1 - 0.0077 16.2 0.8 0.018 14.9 0.1 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OAP54654.1 - 0.045 12.7 0.0 0.058 12.3 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain tRNA-synt_1 PF00133.22 OAP54655.1 - 7.1e-38 130.2 0.0 1e-28 100.0 0.0 2.5 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 OAP54655.1 - 1.2e-17 63.8 0.4 1.8e-10 40.2 0.0 2.6 3 0 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 OAP54655.1 - 5.3e-10 39.4 0.3 1.3e-09 38.2 0.3 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 OAP54655.1 - 2.8e-07 30.2 0.0 5.5e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain BEN PF10523.9 OAP54655.1 - 0.16 12.2 0.4 3.2 8.1 0.0 3.0 3 0 0 3 3 3 0 BEN domain Acetyltransf_8 PF13523.6 OAP54656.1 - 1.7e-49 167.3 0.0 2.4e-49 166.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 OAP54656.1 - 0.011 16.5 0.0 0.021 15.5 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain ARTD15_N PF18084.1 OAP54656.1 - 0.75 10.1 2.4 0.67 10.3 0.3 1.9 2 0 0 2 2 2 0 ARTD15 N-terminal domain OCD_Mu_crystall PF02423.15 OAP54657.1 - 3.6e-16 59.0 0.6 8e-14 51.3 0.0 3.5 2 1 0 3 3 3 2 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.20 OAP54657.1 - 1.2e-07 31.9 0.0 0.00019 21.5 0.0 3.2 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase ATF7IP_BD PF16788.5 OAP54657.1 - 6.6 6.8 5.7 10 6.1 5.7 1.3 1 0 0 1 1 1 0 ATF-interacting protein binding domain MFS_1 PF07690.16 OAP54658.1 - 1.1e-24 87.0 31.8 1.1e-24 87.0 31.8 2.3 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_5 PF05631.14 OAP54658.1 - 0.00023 20.2 0.1 0.00047 19.2 0.1 1.4 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM Clat_adaptor_s PF01217.20 OAP54660.1 - 4.6e-44 149.8 0.0 7.9e-44 149.0 0.0 1.4 1 1 0 1 1 1 1 Clathrin adaptor complex small chain MMR_HSR1 PF01926.23 OAP54661.1 - 2.9e-17 62.8 0.0 4.9e-17 62.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OAP54661.1 - 1.1e-05 25.1 0.0 0.00016 21.3 0.0 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OAP54661.1 - 9.1e-05 22.4 0.0 0.0004 20.3 0.0 1.9 2 0 0 2 2 2 1 RsgA GTPase FeoB_N PF02421.18 OAP54661.1 - 9.5e-05 22.0 0.1 0.00022 20.8 0.1 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 OAP54661.1 - 0.00044 20.4 0.8 0.018 15.1 0.1 2.6 3 0 0 3 3 3 1 Dynamin family Septin PF00735.18 OAP54661.1 - 0.00045 19.6 0.0 0.00073 18.9 0.0 1.2 1 0 0 1 1 1 1 Septin SRPRB PF09439.10 OAP54661.1 - 0.0035 16.8 0.0 0.0072 15.8 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_29 PF13555.6 OAP54661.1 - 0.03 14.1 0.0 0.079 12.7 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Roc PF08477.13 OAP54661.1 - 0.045 14.0 0.0 0.09 13.0 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase WD40 PF00400.32 OAP54662.1 - 5e-42 141.1 13.5 4.4e-06 27.3 0.2 7.7 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box PF00646.33 OAP54662.1 - 4.7e-12 45.5 0.1 1.1e-11 44.3 0.1 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 OAP54662.1 - 6.4e-12 45.2 0.1 1.4e-11 44.1 0.1 1.6 1 0 0 1 1 1 1 F-box-like BBS2_Mid PF14783.6 OAP54662.1 - 3.3e-05 23.9 0.2 8.5 6.5 0.0 4.8 5 1 1 6 6 6 2 Ciliary BBSome complex subunit 2, middle region ANAPC4_WD40 PF12894.7 OAP54662.1 - 4e-05 23.8 1.6 3.5 8.0 0.0 5.0 2 2 4 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OAP54662.1 - 0.002 16.9 3.2 4.7 5.7 0.0 4.8 4 1 1 6 6 6 2 Nucleoporin Nup120/160 F-box_4 PF15966.5 OAP54662.1 - 0.0055 16.6 0.0 0.014 15.3 0.0 1.7 1 0 0 1 1 1 1 F-box PQQ_2 PF13360.6 OAP54662.1 - 0.041 13.5 0.4 0.32 10.5 0.1 2.3 2 0 0 2 2 2 0 PQQ-like domain WD40_like PF17005.5 OAP54662.1 - 0.056 12.8 0.2 7.2 5.8 0.0 2.3 2 0 0 2 2 2 0 WD40-like domain KCT2 PF17818.1 OAP54662.1 - 0.11 12.6 0.7 0.38 10.8 0.2 2.0 2 0 0 2 2 2 0 Keratinocyte-associated gene product FliG_C PF01706.16 OAP54662.1 - 0.18 12.0 0.0 0.38 11.0 0.0 1.4 1 0 0 1 1 1 0 FliG C-terminal domain HORMA PF02301.18 OAP54663.1 - 3.7e-38 131.3 0.0 6.5e-38 130.4 0.0 1.4 1 0 0 1 1 1 1 HORMA domain PHD PF00628.29 OAP54663.1 - 0.00063 19.6 13.2 0.0016 18.2 13.2 1.7 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 OAP54663.1 - 3.2 7.4 10.8 1.3 8.7 7.5 2.0 2 0 0 2 2 2 0 PHD-finger Nuc_sug_transp PF04142.15 OAP54665.1 - 2.4e-95 319.4 7.4 2.9e-95 319.0 7.4 1.1 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 OAP54665.1 - 8.5e-05 21.9 13.6 0.0059 15.9 1.2 2.4 2 0 0 2 2 2 2 UAA transporter family EamA PF00892.20 OAP54665.1 - 0.00032 20.9 10.9 0.00032 20.9 10.9 3.2 2 2 0 2 2 2 1 EamA-like transporter family EmrE PF13536.6 OAP54665.1 - 0.0014 18.3 6.3 0.037 13.6 0.5 2.5 2 0 0 2 2 2 2 Putative multidrug resistance efflux transporter TPT PF03151.16 OAP54665.1 - 0.0078 15.6 2.4 0.0078 15.6 2.4 2.2 2 0 0 2 2 2 1 Triose-phosphate Transporter family Sec63 PF02889.16 OAP54666.1 - 2.1e-28 99.2 0.0 3.2e-28 98.6 0.0 1.3 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.29 OAP54666.1 - 2e-24 86.3 0.0 4.6e-24 85.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 OAP54666.1 - 6.6e-13 49.0 0.1 5.1e-12 46.1 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 OAP54666.1 - 2.6e-07 31.0 0.0 7.5e-07 29.5 0.0 1.8 1 1 0 1 1 1 1 Helicase conserved C-terminal domain AAA_19 PF13245.6 OAP54666.1 - 0.00067 20.0 0.1 0.011 16.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 OAP54666.1 - 0.00083 19.1 0.0 0.0026 17.5 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 OAP54666.1 - 0.0048 17.2 0.0 0.015 15.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 OAP54666.1 - 0.019 14.5 2.0 0.029 13.9 0.0 2.2 3 0 0 3 3 3 0 UvrD/REP helicase N-terminal domain T2SSE PF00437.20 OAP54666.1 - 0.03 13.4 0.0 0.06 12.4 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein ADH_N PF08240.12 OAP54667.1 - 4.5e-21 74.8 0.9 8.3e-21 73.9 0.9 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAP54667.1 - 2.7e-17 62.9 0.0 4.8e-17 62.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 OAP54667.1 - 5.9e-05 22.5 0.1 9.8e-05 21.8 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 OAP54667.1 - 0.00012 21.4 0.0 0.00019 20.8 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 OAP54667.1 - 0.0087 16.0 0.1 0.013 15.4 0.1 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 OAP54667.1 - 0.023 14.9 0.1 0.038 14.2 0.1 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase PGAP1 PF07819.13 OAP54668.1 - 1.1e-87 293.6 0.1 1.9e-87 292.8 0.1 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 OAP54668.1 - 1e-06 29.5 0.1 2.5e-06 28.3 0.1 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Palm_thioest PF02089.15 OAP54668.1 - 0.0002 21.3 0.0 0.00041 20.3 0.0 1.6 2 0 0 2 2 2 1 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.20 OAP54668.1 - 0.00067 19.4 0.1 0.0013 18.4 0.1 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF676 PF05057.14 OAP54668.1 - 0.0024 17.4 0.0 0.0046 16.5 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 OAP54668.1 - 0.0033 16.7 0.0 0.0064 15.8 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 LCAT PF02450.15 OAP54668.1 - 0.011 14.9 0.0 0.019 14.1 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase LIDHydrolase PF10230.9 OAP54668.1 - 0.33 10.5 1.4 0.64 9.5 0.0 2.1 2 1 1 3 3 3 0 Lipid-droplet associated hydrolase DUF4050 PF13259.6 OAP54670.1 - 9.9e-52 175.9 3.9 2.5e-51 174.6 3.9 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF4050) DUF3760 PF12586.8 OAP54671.1 - 0.13 12.4 0.1 0.28 11.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3760) HhH-GPD PF00730.25 OAP54672.1 - 2.5e-10 40.8 0.0 9.7e-10 38.9 0.0 2.0 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 OAP54672.1 - 0.067 13.1 0.0 0.21 11.5 0.0 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix motif SPATIAL PF15256.6 OAP54672.1 - 3.9 7.7 8.6 8.6 6.6 8.6 1.5 1 0 0 1 1 1 0 SPATIAL Sel1 PF08238.12 OAP54673.1 - 1.2e-11 44.9 5.1 0.017 15.8 0.0 3.8 4 0 0 4 4 4 3 Sel1 repeat FR47 PF08445.10 OAP54673.1 - 4.2e-06 26.6 0.1 0.0079 16.1 0.0 2.4 2 0 0 2 2 2 2 FR47-like protein Acetyltransf_3 PF13302.7 OAP54673.1 - 0.046 14.4 0.0 0.15 12.7 0.0 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAP54673.1 - 0.13 12.5 0.0 1.2 9.3 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family Pkinase PF00069.25 OAP54674.1 - 2.7e-23 82.7 0.0 3.4e-23 82.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP54674.1 - 7.6e-11 41.8 0.0 1.2e-10 41.2 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OAP54674.1 - 1.5e-05 25.1 0.2 0.14 12.0 0.1 2.5 1 1 0 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OAP54674.1 - 0.0011 17.9 0.0 0.0015 17.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase ABC1 PF03109.16 OAP54674.1 - 0.032 14.4 0.0 0.089 13.0 0.0 1.7 1 0 0 1 1 1 0 ABC1 family AA_permease PF00324.21 OAP54676.1 - 3.7e-107 358.9 44.1 4.5e-107 358.6 44.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAP54676.1 - 2.1e-28 99.4 50.3 2.8e-28 98.9 50.3 1.1 1 0 0 1 1 1 1 Amino acid permease DAO PF01266.24 OAP54677.1 - 3e-35 122.5 0.1 4.5e-35 121.9 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Fungal_trans PF04082.18 OAP54677.1 - 2.8e-06 26.5 0.9 6e-06 25.5 0.9 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain NAD_binding_8 PF13450.6 OAP54677.1 - 8.7e-06 25.9 0.0 4.7e-05 23.5 0.0 2.3 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 OAP54677.1 - 6.2e-05 22.0 0.1 0.00016 20.7 0.1 1.6 1 1 0 1 1 1 1 Tryptophan halogenase FAD_binding_3 PF01494.19 OAP54677.1 - 0.0037 16.6 0.1 0.0072 15.6 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 OAP54677.1 - 0.0097 15.2 0.0 0.026 13.7 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAP54677.1 - 0.013 14.6 1.8 0.031 13.3 0.0 2.3 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_3 PF13738.6 OAP54677.1 - 0.025 13.8 0.0 0.042 13.1 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase KR PF08659.10 OAP54677.1 - 0.04 13.8 0.0 0.09 12.7 0.0 1.6 1 0 0 1 1 1 0 KR domain Thi4 PF01946.17 OAP54677.1 - 0.043 13.0 0.0 0.078 12.2 0.0 1.3 1 0 0 1 1 1 0 Thi4 family TrkA_N PF02254.18 OAP54677.1 - 0.051 13.8 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain UDPG_MGDP_dh_N PF03721.14 OAP54677.1 - 0.072 12.6 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Sacchrp_dh_NADP PF03435.18 OAP54677.1 - 0.097 12.9 0.2 0.26 11.6 0.0 1.8 2 0 0 2 2 1 0 Saccharopine dehydrogenase NADP binding domain Glu_dehyd_C PF16912.5 OAP54677.1 - 0.1 12.1 0.0 0.26 10.8 0.0 1.6 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus ASFV_J13L PF05568.11 OAP54677.1 - 0.13 12.0 1.3 0.24 11.1 1.3 1.3 1 0 0 1 1 1 0 African swine fever virus J13L protein Shikimate_DH PF01488.20 OAP54677.1 - 0.14 12.3 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 OAP54677.1 - 0.19 11.3 0.0 0.37 10.4 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DAO PF01266.24 OAP54678.1 - 9e-42 143.9 0.1 1e-41 143.7 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAP54678.1 - 1.8e-05 24.9 0.0 4.7e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAP54678.1 - 0.0044 16.3 0.0 1.5 8.0 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 OAP54678.1 - 0.01 15.9 0.0 0.16 12.1 0.0 2.5 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.6 OAP54678.1 - 0.013 15.5 0.0 5.9 6.9 0.1 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 OAP54678.1 - 0.013 14.6 2.2 1.5 7.8 0.2 2.1 2 0 0 2 2 2 0 FAD binding domain FAD_binding_3 PF01494.19 OAP54678.1 - 0.018 14.3 0.0 0.019 14.2 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.22 OAP54678.1 - 0.095 11.8 0.1 5.5 5.9 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Trp_halogenase PF04820.14 OAP54678.1 - 0.12 11.2 0.7 6.4 5.5 0.1 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Transglut_core PF01841.19 OAP54678.1 - 0.13 12.8 0.8 0.46 10.9 0.8 1.9 1 1 0 1 1 1 0 Transglutaminase-like superfamily Sulfate_transp PF00916.20 OAP54679.1 - 8e-109 363.9 20.0 1.3e-108 363.2 20.0 1.3 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 OAP54679.1 - 3.9e-09 36.2 0.0 8.4e-09 35.1 0.0 1.5 1 0 0 1 1 1 1 STAS domain SNN_transmemb PF09049.10 OAP54679.1 - 0.019 14.9 0.7 0.019 14.9 0.7 2.6 3 0 0 3 3 3 0 Stannin transmembrane MFS_MOT1 PF16983.5 OAP54679.1 - 0.58 10.6 20.3 0.027 14.9 3.0 3.2 2 1 1 3 3 3 0 Molybdate transporter of MFS superfamily DnaJ_C PF01556.18 OAP54680.1 - 5.1e-39 133.7 0.1 6.6e-39 133.3 0.1 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 OAP54680.1 - 2.5e-25 88.4 1.8 4.3e-25 87.6 1.8 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 OAP54680.1 - 1.8e-15 57.0 18.6 3.1e-15 56.3 18.6 1.4 1 0 0 1 1 1 1 DnaJ central domain LPD39 PF18858.1 OAP54680.1 - 0.13 12.3 0.6 0.22 11.6 0.6 1.3 1 0 0 1 1 1 0 Large polyvalent protein associated domain 39 zf_Rg PF17915.1 OAP54680.1 - 0.38 10.2 7.0 0.13 11.7 0.6 2.7 2 0 0 2 2 2 0 Reverse gyrase zinc finger Zn_ribbon_SprT PF17283.2 OAP54680.1 - 0.65 10.0 5.5 0.85 9.6 2.4 2.4 2 0 0 2 2 2 0 SprT-like zinc ribbon domain HypA PF01155.19 OAP54680.1 - 1.6 8.8 10.7 1.8 8.6 2.1 2.4 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc-ribbons_6 PF07191.12 OAP54680.1 - 4.6 7.3 9.5 6.6 6.8 1.7 2.3 1 1 1 2 2 2 0 zinc-ribbons DUF2614 PF11023.8 OAP54680.1 - 5.1 7.2 6.8 4.4 7.4 0.6 2.2 1 1 1 2 2 2 0 Zinc-ribbon containing domain Clr5 PF14420.6 OAP54681.1 - 1.8e-17 63.3 0.9 3.3e-17 62.4 0.9 1.5 1 0 0 1 1 1 1 Clr5 domain p450 PF00067.22 OAP54682.1 - 1.4e-39 136.2 0.0 3.7e-39 134.8 0.0 1.6 2 0 0 2 2 2 1 Cytochrome P450 TetR_C_31 PF17940.1 OAP54682.1 - 0.029 14.6 0.1 0.1 12.8 0.1 1.9 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Sde2_N_Ubi PF13019.6 OAP54683.1 - 2e-57 193.6 1.1 2.9e-57 193.1 1.1 1.2 1 0 0 1 1 1 1 Silencing defective 2 N-terminal ubiquitin domain DOCK_N PF16172.5 OAP54684.1 - 4.2e-86 289.2 1.0 1.4e-85 287.5 0.0 2.0 2 0 0 2 2 2 1 DOCK N-terminus DOCK-C2 PF14429.6 OAP54684.1 - 1.6e-29 103.2 0.2 6.6e-29 101.1 0.0 2.2 3 0 0 3 3 3 1 C2 domain in Dock180 and Zizimin proteins SH3_9 PF14604.6 OAP54684.1 - 3.8e-06 26.7 0.0 1.1e-05 25.1 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 OAP54684.1 - 1.4e-05 24.6 0.0 3.1e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 SH3 domain Suc_Fer-like PF06999.12 OAP54685.1 - 1.5e-66 224.0 0.0 2e-66 223.6 0.0 1.2 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Spt20 PF12090.8 OAP54685.1 - 0.76 9.3 7.1 1.1 8.8 7.1 1.1 1 0 0 1 1 1 0 Spt20 family Dicty_REP PF05086.12 OAP54685.1 - 2.9 5.7 5.5 3.9 5.3 5.5 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SART-1 PF03343.13 OAP54686.1 - 2.5e-156 521.9 72.7 3e-156 521.6 72.7 1.0 1 0 0 1 1 1 1 SART-1 family Aminotran_1_2 PF00155.21 OAP54687.1 - 4.7e-92 308.9 0.0 5.7e-92 308.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Hpt PF01627.23 OAP54688.1 - 2.3e-11 43.8 0.1 3.6e-11 43.2 0.1 1.3 1 0 0 1 1 1 1 Hpt domain zf-H2C2_2 PF13465.6 OAP54689.1 - 1.2e-18 66.6 21.4 2.2e-06 27.9 0.3 5.4 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2 PF00096.26 OAP54689.1 - 8.3e-17 60.6 35.1 6.5e-05 23.2 1.1 4.9 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAP54689.1 - 3e-07 30.7 33.5 0.027 15.3 0.9 5.0 5 0 0 5 5 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OAP54689.1 - 0.00015 21.9 4.9 7.4 7.0 0.1 4.4 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OAP54689.1 - 0.0036 17.6 10.0 0.34 11.4 0.1 4.8 4 1 1 5 5 5 1 Zinc-finger of C2H2 type FOXP-CC PF16159.5 OAP54689.1 - 0.0038 17.8 6.1 0.26 11.9 0.2 3.5 3 1 1 4 4 3 1 FOXP coiled-coil domain zf-C2H2_11 PF16622.5 OAP54689.1 - 0.0094 15.7 0.5 0.0094 15.7 0.5 3.4 3 0 0 3 3 3 1 zinc-finger C2H2-type C1_4 PF07975.12 OAP54689.1 - 1.1 9.5 7.0 5.7 7.2 1.9 2.6 2 1 0 2 2 2 0 TFIIH C1-like domain DUF2256 PF10013.9 OAP54689.1 - 1.3 9.2 6.9 8.2 6.6 0.0 3.4 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-LYAR PF08790.11 OAP54689.1 - 2.8 7.9 4.8 62 3.6 0.1 3.6 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger Zn-ribbon_8 PF09723.10 OAP54689.1 - 4.6 7.4 8.1 11 6.2 0.5 3.3 2 2 1 3 3 3 0 Zinc ribbon domain Sec3_C PF09763.9 OAP54690.1 - 9.5e-190 632.5 20.6 1.3e-189 632.1 20.6 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.6 OAP54690.1 - 1.6e-25 89.1 0.1 5.1e-25 87.4 0.0 2.0 2 0 0 2 2 2 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Mg_trans_NIPA PF05653.14 OAP54691.1 - 0.22 10.6 0.0 0.31 10.1 0.0 1.1 1 0 0 1 1 1 0 Magnesium transporter NIPA RhoGAP PF00620.27 OAP54692.1 - 9.2e-48 161.9 0.4 2.8e-47 160.4 0.0 2.1 2 0 0 2 2 2 1 RhoGAP domain LIM PF00412.22 OAP54692.1 - 2.6e-14 53.2 17.8 1.4e-09 38.0 1.8 2.4 2 0 0 2 2 2 2 LIM domain DUF4686 PF15742.5 OAP54692.1 - 0.32 10.1 14.7 0.031 13.4 1.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4686) Zn-ribbon_8 PF09723.10 OAP54692.1 - 6.7 6.9 19.2 1.7 8.8 1.2 4.2 3 1 1 4 4 4 0 Zinc ribbon domain DUF2730 PF10805.8 OAP54692.1 - 8.9 6.5 8.7 23 5.1 0.6 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2730) CLASP_N PF12348.8 OAP54693.1 - 7.3e-43 146.7 0.0 1.4e-42 145.8 0.0 1.4 1 0 0 1 1 1 1 CLASP N terminal HEAT_EZ PF13513.6 OAP54693.1 - 0.0093 16.5 0.1 0.12 12.9 0.0 2.6 2 0 0 2 2 2 1 HEAT-like repeat Excalibur PF05901.11 OAP54693.1 - 0.046 14.3 0.0 0.11 13.1 0.0 1.7 1 0 0 1 1 1 0 Excalibur calcium-binding domain BSP PF04450.12 OAP54694.1 - 6.1e-65 218.9 0.0 7.2e-65 218.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase of plants and bacteria RL10P_insert PF17777.1 OAP54695.1 - 4.6e-22 77.8 0.1 1.7e-21 76.0 0.0 1.9 2 0 0 2 2 2 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_60s PF00428.19 OAP54695.1 - 3.8e-17 62.7 8.7 9.5e-17 61.4 7.1 2.2 2 0 0 2 2 2 1 60s Acidic ribosomal protein Ribosomal_L10 PF00466.20 OAP54695.1 - 2.9e-15 56.2 0.0 7.1e-15 55.0 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L10 WD40 PF00400.32 OAP54696.1 - 0.068 14.1 0.3 45 5.1 0.0 4.4 5 0 0 5 5 5 0 WD domain, G-beta repeat FA_desaturase PF00487.24 OAP54696.1 - 0.16 11.8 0.0 0.25 11.1 0.0 1.2 1 0 0 1 1 1 0 Fatty acid desaturase DUF3306 PF11748.8 OAP54696.1 - 1.1 10.2 5.7 0.15 12.9 0.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) URO-D PF01208.17 OAP54697.1 - 2.2e-111 372.4 0.0 2.6e-111 372.1 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) dCMP_cyt_deam_1 PF00383.23 OAP54698.1 - 4.8e-12 45.6 0.1 6.8e-12 45.2 0.1 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 OAP54698.1 - 1.1e-09 38.2 0.0 1.6e-09 37.6 0.0 1.2 1 1 0 1 1 1 1 MafB19-like deaminase SNAD4 PF18750.1 OAP54698.1 - 0.0093 16.1 0.0 0.028 14.5 0.0 1.8 1 1 0 2 2 2 1 Secreted Novel AID/APOBEC-like Deaminase 4 Bd3614-deam PF14439.6 OAP54698.1 - 0.017 15.2 0.9 0.024 14.7 0.9 1.5 1 1 0 1 1 1 0 Bd3614-like deaminase NAD1 PF18778.1 OAP54698.1 - 0.031 14.4 0.1 0.16 12.1 0.1 1.9 1 1 0 1 1 1 0 Novel AID APOBEC clade 1 APOBEC2 PF18772.1 OAP54698.1 - 0.046 13.8 0.0 0.3 11.1 0.0 1.9 1 1 0 1 1 1 0 APOBEC2 NAD2 PF18782.1 OAP54698.1 - 0.067 13.3 0.0 0.14 12.3 0.0 1.7 1 1 0 1 1 1 0 Novel AID APOBEC clade 2 APOBEC_N PF08210.11 OAP54698.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.5 1 1 0 1 1 1 0 APOBEC-like N-terminal domain adh_short PF00106.25 OAP54699.1 - 6.5e-24 84.5 0.0 3.2e-23 82.2 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP54699.1 - 8.4e-19 68.1 0.3 6.3e-09 35.7 0.1 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP54699.1 - 7.6e-05 22.7 0.0 0.00086 19.3 0.0 2.2 2 0 0 2 2 2 1 KR domain SH3_9 PF14604.6 OAP54700.1 - 2.3e-11 43.4 0.0 4e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 OAP54700.1 - 2.9e-08 33.2 0.0 4.3e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 OAP54700.1 - 4.3e-07 29.5 0.0 7e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain VSP PF03302.13 OAP54700.1 - 9.6e-06 24.7 0.8 1.6e-05 23.9 0.8 1.3 1 0 0 1 1 1 1 Giardia variant-specific surface protein Pkinase PF00069.25 OAP54701.1 - 3.2e-42 144.7 0.0 4.8e-42 144.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP54701.1 - 1.5e-20 73.5 0.0 2.3e-20 73.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OAP54701.1 - 1.1e-05 25.5 0.5 0.005 16.8 0.0 2.4 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.6 OAP54701.1 - 0.0041 16.5 0.0 0.0082 15.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OAP54701.1 - 0.011 15.1 0.0 0.03 13.7 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OAP54701.1 - 0.019 13.7 0.0 0.025 13.4 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Choline_kinase PF01633.20 OAP54701.1 - 0.21 11.2 0.0 0.35 10.4 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase muHD PF10291.9 OAP54702.1 - 8.6e-69 231.9 0.0 1.2e-68 231.4 0.0 1.2 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.23 OAP54702.1 - 2.2e-08 34.3 0.0 8.3e-08 32.4 0.0 2.1 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain Adap_comp_sub PF00928.21 OAP54702.1 - 3.7e-07 29.8 0.0 2.4e-05 23.8 0.0 2.2 2 0 0 2 2 2 2 Adaptor complexes medium subunit family Laminin_II PF06009.12 OAP54702.1 - 0.23 11.5 2.9 0.13 12.3 0.3 1.8 2 0 0 2 2 2 0 Laminin Domain II TFIIF_alpha PF05793.12 OAP54703.1 - 0.013 14.1 57.8 0.21 10.1 57.9 2.9 1 1 1 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PAP_assoc PF03828.19 OAP54704.1 - 9.6e-18 64.2 0.0 2.3e-17 62.9 0.0 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 OAP54704.1 - 0.054 13.8 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 Nucleotidyltransferase domain adh_short PF00106.25 OAP54705.1 - 3.8e-32 111.3 0.0 5.7e-32 110.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP54705.1 - 1.2e-18 67.6 0.0 1.9e-18 66.9 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP54705.1 - 9.6e-08 32.1 0.4 6.3e-05 23.0 0.1 2.2 2 0 0 2 2 2 2 KR domain DUF1776 PF08643.10 OAP54705.1 - 0.0018 17.7 0.0 0.003 17.0 0.0 1.4 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) 3Beta_HSD PF01073.19 OAP54705.1 - 0.0018 17.4 0.0 0.0026 16.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 OAP54705.1 - 0.0074 15.8 0.1 0.024 14.1 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family DUF1168 PF06658.12 OAP54706.1 - 6e-37 126.5 16.1 7.7e-37 126.1 16.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) Zip PF02535.22 OAP54706.1 - 0.16 11.1 3.1 0.21 10.8 3.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter PPL5 PF18168.1 OAP54706.1 - 0.59 9.4 6.7 0.78 9.0 6.7 1.1 1 0 0 1 1 1 0 Prim-pol family 5 Presenilin PF01080.17 OAP54706.1 - 5.2 5.7 10.9 6.6 5.4 10.9 1.1 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.12 OAP54706.1 - 5.9 6.6 11.7 7.7 6.2 11.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Hid1 PF12722.7 OAP54706.1 - 8.9 4.3 6.1 11 4.0 6.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Mur_ligase_M PF08245.12 OAP54707.1 - 1.2e-05 25.4 0.2 3.6e-05 23.8 0.2 1.7 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 OAP54707.1 - 0.00024 21.3 0.0 0.00056 20.1 0.0 1.6 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain ECH_1 PF00378.20 OAP54708.1 - 2.4e-36 125.4 0.0 3.5e-36 124.8 0.0 1.2 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAP54708.1 - 6.2e-15 55.5 0.0 7.1e-15 55.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase TPR_12 PF13424.6 OAP54709.1 - 7.8e-101 330.5 62.4 2e-18 66.4 3.8 8.7 3 1 6 9 9 9 8 Tetratricopeptide repeat TPR_10 PF13374.6 OAP54709.1 - 1.3e-95 311.1 27.7 4.4e-14 51.8 0.4 9.6 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_1 PF00515.28 OAP54709.1 - 5.7e-41 136.7 48.1 8.6e-05 22.2 0.6 9.9 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_2 PF07719.17 OAP54709.1 - 1.2e-37 125.0 33.5 0.00053 19.9 0.1 10.1 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_8 PF13181.6 OAP54709.1 - 1.3e-36 121.7 32.8 0.0023 18.0 0.1 9.9 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_7 PF13176.6 OAP54709.1 - 2.7e-36 121.0 20.9 0.0016 18.3 0.0 9.7 10 0 0 10 10 9 8 Tetratricopeptide repeat TPR_MalT PF17874.1 OAP54709.1 - 1.2e-31 110.3 24.5 4.1e-09 36.3 0.3 4.7 2 1 3 5 5 5 4 MalT-like TPR region TPR_14 PF13428.6 OAP54709.1 - 2.1e-24 84.1 24.8 0.054 14.3 0.1 10.7 9 2 2 11 11 10 8 Tetratricopeptide repeat TPR_16 PF13432.6 OAP54709.1 - 4.7e-20 72.0 25.9 0.00084 19.9 2.5 8.6 7 1 0 7 7 7 6 Tetratricopeptide repeat TPR_11 PF13414.6 OAP54709.1 - 5.8e-17 61.1 34.9 0.059 13.1 0.2 8.9 8 0 0 8 8 8 7 TPR repeat TPR_17 PF13431.6 OAP54709.1 - 7.3e-15 54.2 17.8 1.1 9.8 0.1 10.6 10 0 0 10 10 10 5 Tetratricopeptide repeat Ribosomal_S7 PF00177.21 OAP54709.1 - 2e-12 47.0 0.0 3.1 7.4 0.0 7.3 2 1 6 8 8 8 4 Ribosomal protein S7p/S5e TPR_4 PF07721.14 OAP54709.1 - 2.5e-12 46.1 0.0 16 6.5 0.0 8.9 8 0 0 8 8 8 0 Tetratricopeptide repeat RPN7 PF10602.9 OAP54709.1 - 2.3e-10 40.4 16.9 0.92 9.2 0.1 8.7 4 3 4 9 9 9 4 26S proteasome subunit RPN7 HET PF06985.11 OAP54709.1 - 8.4e-10 39.2 9.0 2.2e-08 34.6 0.3 3.0 2 1 1 3 3 2 2 Heterokaryon incompatibility protein (HET) NB-ARC PF00931.22 OAP54709.1 - 1.7e-09 37.2 0.0 4.8e-09 35.8 0.0 1.6 1 1 0 1 1 1 1 NB-ARC domain TPR_21 PF09976.9 OAP54709.1 - 3.5e-09 36.6 23.7 4.2 7.0 0.1 8.9 2 1 6 8 8 8 3 Tetratricopeptide repeat-like domain TPR_19 PF14559.6 OAP54709.1 - 7.6e-08 32.8 30.4 0.038 14.5 1.5 5.9 3 2 6 9 9 8 6 Tetratricopeptide repeat AAA_16 PF13191.6 OAP54709.1 - 6.1e-07 30.0 0.1 1.2e-05 25.8 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain DUF2225 PF09986.9 OAP54709.1 - 2.9e-06 27.1 8.6 0.0044 16.8 0.2 4.6 3 1 3 6 6 6 2 Uncharacterized protein conserved in bacteria (DUF2225) ATPase_2 PF01637.18 OAP54709.1 - 0.00022 21.2 0.0 0.00036 20.5 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 OAP54709.1 - 0.11 12.8 0.0 0.38 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain RPN6_C_helix PF18503.1 OAP54709.1 - 0.59 9.9 8.3 23 4.8 0.1 4.3 4 0 0 4 4 3 0 26S proteasome subunit RPN6 C-terminal helix domain LAGLIDADG_2 PF03161.13 OAP54709.1 - 0.65 10.0 3.0 1.2e+02 2.7 0.0 5.0 4 1 3 7 7 6 0 LAGLIDADG DNA endonuclease family Glyoxalase_4 PF13669.6 OAP54710.1 - 0.015 15.5 0.2 1.5 9.1 0.0 2.7 3 0 0 3 3 3 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 OAP54710.1 - 0.053 13.6 0.0 0.13 12.4 0.0 1.7 1 0 0 1 1 1 0 Glyoxalase-like domain Cu-oxidase_3 PF07732.15 OAP54711.1 - 4.4e-43 146.1 7.7 1.9e-41 140.8 1.0 2.6 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 OAP54711.1 - 3.1e-37 127.4 9.3 4.9e-35 120.3 3.0 3.8 3 2 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 OAP54711.1 - 2.1e-35 122.2 1.8 4.3e-29 101.7 0.0 3.1 4 0 0 4 4 4 2 Multicopper oxidase AATF-Che1 PF13339.6 OAP54715.1 - 4.4e-31 108.4 0.4 4.4e-31 108.4 0.4 2.2 2 0 0 2 2 2 1 Apoptosis antagonizing transcription factor TRAUB PF08164.12 OAP54715.1 - 1.3e-26 93.0 0.0 3.9e-26 91.4 0.0 1.9 1 0 0 1 1 1 1 Apoptosis-antagonizing transcription factor, C-terminal RRN3 PF05327.11 OAP54715.1 - 7.5 5.0 5.8 14 4.1 5.8 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Rad4 PF03835.15 OAP54716.1 - 5.6e-37 126.7 0.1 1.4e-36 125.4 0.1 1.7 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.9 OAP54716.1 - 4.7e-27 94.2 0.1 8.6e-27 93.4 0.1 1.4 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 OAP54716.1 - 1.4e-19 69.7 0.2 2.5e-19 68.8 0.2 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 OAP54716.1 - 9.2e-17 61.8 1.5 9.2e-17 61.8 1.5 3.2 3 1 0 3 3 3 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.19 OAP54716.1 - 0.0063 16.9 0.1 0.044 14.2 0.0 2.4 2 0 0 2 2 2 1 Transglutaminase-like superfamily FAM184 PF15665.5 OAP54717.1 - 0.0001 22.2 28.9 0.0001 22.2 28.9 8.5 2 1 6 8 8 8 2 Family with sequence similarity 184, A and B Golgin_A5 PF09787.9 OAP54717.1 - 0.0012 18.3 22.5 0.0012 18.3 22.5 9.0 1 1 6 8 8 8 2 Golgin subfamily A member 5 DUF2746 PF10874.8 OAP54717.1 - 0.5 10.8 4.5 10 6.6 0.0 4.8 3 1 2 5 5 5 0 Protein of unknown function (DUF2746) Pox_A_type_inc PF04508.12 OAP54717.1 - 1.2 9.2 9.3 4.5 7.3 0.4 6.0 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat PTPA PF03095.15 OAP54719.1 - 7.5e-113 376.9 0.0 9e-113 376.7 0.0 1.1 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Rhamno_transf PF11316.8 OAP54719.1 - 0.091 12.1 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Putative rhamnosyl transferase DUF572 PF04502.13 OAP54720.1 - 7.5e-68 229.6 0.0 8.7e-68 229.4 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) Nucleo_P87 PF07267.11 OAP54720.1 - 2 7.2 3.7 3.2 6.5 3.7 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 zf-RING_UBOX PF13445.6 OAP54721.1 - 2.2e-07 30.7 4.0 0.00072 19.5 0.2 2.9 2 1 0 2 2 2 2 RING-type zinc-finger zf-RING_5 PF14634.6 OAP54721.1 - 2e-05 24.5 4.2 0.00097 19.0 1.5 2.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 OAP54721.1 - 0.00058 19.7 5.3 0.035 14.0 0.5 3.0 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-NOSIP PF15906.5 OAP54721.1 - 0.0009 19.3 0.0 0.0016 18.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein zf-RING_2 PF13639.6 OAP54721.1 - 0.63 10.4 12.5 0.4 11.1 2.9 3.3 2 2 0 2 2 2 0 Ring finger domain zf-B_box PF00643.24 OAP54721.1 - 0.82 9.9 10.9 1.1 9.5 0.2 4.3 4 0 0 4 4 4 0 B-box zinc finger FYVE PF01363.21 OAP54721.1 - 0.99 9.6 11.8 0.11 12.6 1.7 3.5 2 2 1 3 3 3 0 FYVE zinc finger Prok-RING_4 PF14447.6 OAP54721.1 - 2.7 7.9 15.0 0.54 10.2 0.6 4.0 4 1 0 4 4 4 0 Prokaryotic RING finger family 4 DZR PF12773.7 OAP54721.1 - 3.1 7.9 11.1 1.6 8.8 0.6 3.3 3 0 0 3 3 3 0 Double zinc ribbon zf-C3HC4_2 PF13923.6 OAP54721.1 - 5.6 6.9 16.0 1.4 8.8 2.5 3.7 3 2 1 4 4 4 0 Zinc finger, C3HC4 type (RING finger) Sedlin_N PF04628.13 OAP54722.1 - 3.9e-40 137.0 0.0 4.7e-40 136.8 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 OAP54722.1 - 6.5e-07 29.4 0.0 9.9e-05 22.3 0.0 2.1 1 1 1 2 2 2 2 Sybindin-like family DUF2040 PF09745.9 OAP54723.1 - 2.6e-37 127.6 18.3 2.6e-37 127.6 18.3 3.9 3 2 0 3 3 3 1 Coiled-coil domain-containing protein 55 (DUF2040) adh_short PF00106.25 OAP54724.1 - 1.6e-42 145.2 0.0 1.9e-42 144.9 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP54724.1 - 3.7e-37 128.1 0.1 4.2e-37 127.9 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP54724.1 - 3.4e-11 43.4 0.5 4.7e-11 42.9 0.5 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAP54724.1 - 0.00018 21.0 0.1 0.00052 19.6 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Ins_P5_2-kin PF06090.12 OAP54725.1 - 3.4e-43 148.4 0.0 1.4e-42 146.3 0.0 1.8 1 1 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase Ank_4 PF13637.6 OAP54727.1 - 6.8e-89 291.2 23.9 1.3e-10 41.6 0.0 11.3 1 1 12 13 13 13 13 Ankyrin repeats (many copies) Ank_2 PF12796.7 OAP54727.1 - 3.4e-84 277.5 9.9 1.5e-16 60.8 1.1 7.2 1 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OAP54727.1 - 3.7e-70 223.5 0.8 6.2e-06 26.2 0.0 14.3 14 0 0 14 14 14 12 Ankyrin repeat Ank_5 PF13857.6 OAP54727.1 - 5.7e-69 227.3 9.2 1.5e-10 41.1 0.1 10.3 3 3 7 10 10 10 10 Ankyrin repeats (many copies) Ank PF00023.30 OAP54727.1 - 1.6e-62 205.3 11.8 1.4e-07 31.6 0.0 14.2 13 1 1 14 14 14 11 Ankyrin repeat PNP_UDP_1 PF01048.20 OAP54727.1 - 3.8e-14 52.5 0.0 7.4e-14 51.6 0.0 1.5 1 0 0 1 1 1 1 Phosphorylase superfamily EcoRII-N PF09217.10 OAP54727.1 - 0.034 13.9 0.0 0.067 12.9 0.0 1.4 1 0 0 1 1 1 0 Restriction endonuclease EcoRII, N-terminal FemAB_like PF04339.12 OAP54727.1 - 0.083 12.0 0.0 0.69 9.0 0.0 2.3 2 0 0 2 2 2 0 Peptidogalycan biosysnthesis/recognition GATase_7 PF13537.6 OAP54727.1 - 0.098 12.6 0.0 2.2e+02 1.7 0.0 4.6 4 1 1 5 5 5 0 Glutamine amidotransferase domain CBM_21 PF03370.13 OAP54731.1 - 6.1e-37 126.2 1.6 1.1e-36 125.4 1.6 1.5 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 OAP54731.1 - 2.6e-11 44.0 2.1 6.2e-11 42.7 2.1 1.6 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) MCM PF00493.23 OAP54732.1 - 7.1e-101 336.0 0.0 1e-100 335.4 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 OAP54732.1 - 9.3e-41 138.6 0.6 1.9e-40 137.6 0.6 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 OAP54732.1 - 2e-29 101.9 0.8 5e-29 100.6 0.8 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 OAP54732.1 - 7.1e-18 65.1 0.0 2.3e-17 63.4 0.0 2.0 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 OAP54732.1 - 3.3e-06 26.6 0.0 0.00013 21.4 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 OAP54732.1 - 1.4e-05 25.1 0.0 3.8e-05 23.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 OAP54732.1 - 0.0012 18.7 0.0 0.0031 17.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) WD40 PF00400.32 OAP54733.1 - 2e-45 151.8 21.2 7e-06 26.7 0.0 8.5 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.7 OAP54733.1 - 1.5e-13 50.4 0.4 2.8e-13 49.5 0.4 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAP54733.1 - 2.8e-12 46.2 0.3 6.4e-12 45.0 0.3 1.7 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.8 OAP54733.1 - 1.1e-10 40.8 7.6 0.018 13.7 0.1 5.8 3 1 3 6 6 6 5 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 OAP54733.1 - 8.6e-07 29.2 0.2 0.63 10.4 0.0 5.2 2 2 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain F-box_4 PF15966.5 OAP54733.1 - 5.7e-06 26.2 0.0 1.5e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 F-box APG17 PF04108.12 OAP54734.1 - 3.1e-113 378.9 7.6 3.7e-113 378.6 7.6 1.0 1 0 0 1 1 1 1 Autophagy protein Apg17 TipAS PF07739.13 OAP54734.1 - 0.056 14.0 1.9 1.1 9.9 0.0 2.8 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain OmpH PF03938.14 OAP54734.1 - 0.056 13.8 14.7 2 8.8 0.1 4.3 4 0 0 4 4 4 0 Outer membrane protein (OmpH-like) NPV_P10 PF05531.12 OAP54734.1 - 0.1 13.0 6.8 2.3 8.7 0.1 3.2 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein LXG PF04740.12 OAP54734.1 - 0.16 11.6 13.1 0.58 9.8 0.3 3.8 3 1 1 4 4 4 0 LXG domain of WXG superfamily DUF1664 PF07889.12 OAP54734.1 - 0.23 11.5 16.9 2.4 8.2 0.8 4.6 3 1 2 5 5 5 0 Protein of unknown function (DUF1664) STAT_alpha PF01017.20 OAP54734.1 - 0.45 10.4 0.1 0.45 10.4 0.1 3.6 3 1 2 5 5 5 0 STAT protein, all-alpha domain Glutaredoxin2_C PF04399.13 OAP54734.1 - 0.49 10.2 0.0 0.49 10.2 0.0 2.5 3 0 0 3 3 3 0 Glutaredoxin 2, C terminal domain Baculo_PEP_C PF04513.12 OAP54734.1 - 0.88 9.6 12.0 4.7 7.2 0.1 4.0 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus YojJ PF10372.9 OAP54734.1 - 0.97 9.6 13.0 2.6 8.2 0.1 4.4 4 0 0 4 4 4 0 Bacterial membrane-spanning protein N-terminus DUF4510 PF14971.6 OAP54734.1 - 1.6 9.0 6.0 2.1 8.7 0.2 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4510) Tektin PF03148.14 OAP54734.1 - 1.8 7.2 17.2 1.6 7.4 0.8 3.8 4 0 0 4 4 4 0 Tektin family Vps54_N PF10475.9 OAP54734.1 - 2.6 7.3 7.8 0.5 9.6 0.1 2.8 4 0 0 4 4 4 0 Vacuolar-sorting protein 54, of GARP complex FH2 PF02181.23 OAP54734.1 - 4 6.4 11.8 0.47 9.5 0.0 3.3 3 1 0 4 4 4 0 Formin Homology 2 Domain MCPsignal PF00015.21 OAP54734.1 - 4.6 7.0 11.4 2.9 7.7 0.1 3.6 4 0 0 4 4 4 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Bacillus_HBL PF05791.11 OAP54734.1 - 5.2 6.9 9.4 6.5 6.5 0.1 3.6 3 1 0 4 4 4 0 Bacillus haemolytic enterotoxin (HBL) PhaP_Bmeg PF09602.10 OAP54734.1 - 6.1 6.8 10.4 5.4 6.9 0.1 3.6 3 1 0 3 3 3 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) RIO1 PF01163.22 OAP54735.1 - 8.9e-70 234.1 1.2 8.9e-70 234.1 1.2 1.7 2 0 0 2 2 2 1 RIO1 family Pkinase_Tyr PF07714.17 OAP54735.1 - 0.077 12.3 0.3 2.2 7.5 0.1 2.3 2 0 0 2 2 2 0 Protein tyrosine kinase SR-25 PF10500.9 OAP54735.1 - 0.43 10.1 16.2 0.026 14.1 10.3 1.9 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein adh_short PF00106.25 OAP54736.1 - 8.6e-35 120.0 0.0 1.1e-34 119.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP54736.1 - 1.2e-26 93.8 0.0 1.7e-26 93.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP54736.1 - 1.6e-07 31.4 0.0 2.5e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 OAP54736.1 - 0.0002 21.3 0.0 0.059 13.3 0.0 2.3 1 1 0 2 2 2 2 NAD(P)H-binding FAD_binding_3 PF01494.19 OAP54737.1 - 9.5e-51 173.1 0.0 1.4e-50 172.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAP54737.1 - 3.1e-09 36.9 0.2 4e-06 26.7 0.1 2.3 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAP54737.1 - 5.2e-09 35.8 0.0 8.1e-09 35.1 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAP54737.1 - 2.5e-06 27.0 0.0 7.8e-05 22.1 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAP54737.1 - 3.3e-06 27.5 0.1 0.001 19.6 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAP54737.1 - 3.6e-06 25.9 0.2 0.00098 17.9 0.0 2.7 3 0 0 3 3 3 1 HI0933-like protein NAD_binding_8 PF13450.6 OAP54737.1 - 3.2e-05 24.0 0.0 7.9e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 OAP54737.1 - 7.5e-05 22.2 0.3 0.18 11.0 0.0 2.8 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 OAP54737.1 - 0.00042 19.8 0.0 0.00078 18.9 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 OAP54737.1 - 0.00044 19.6 0.0 0.00075 18.8 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 OAP54737.1 - 0.0017 17.5 0.0 0.0057 15.8 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 OAP54737.1 - 0.0019 17.5 0.1 0.0044 16.3 0.0 1.6 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 OAP54737.1 - 0.0028 17.0 0.0 0.0059 16.0 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GIDA PF01134.22 OAP54737.1 - 0.0071 15.5 0.1 0.014 14.5 0.0 1.5 2 0 0 2 2 2 1 Glucose inhibited division protein A TrkA_N PF02254.18 OAP54737.1 - 0.0077 16.5 0.1 0.021 15.1 0.0 1.8 2 0 0 2 2 2 1 TrkA-N domain ThiF PF00899.21 OAP54737.1 - 0.0096 15.3 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 1 ThiF family NAD_binding_7 PF13241.6 OAP54737.1 - 0.013 16.0 0.1 0.078 13.4 0.0 2.2 2 1 0 2 2 2 0 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.14 OAP54737.1 - 0.013 15.1 0.0 0.026 14.1 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain K_oxygenase PF13434.6 OAP54737.1 - 0.02 14.1 0.1 5.1 6.1 0.0 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) 3HCDH_N PF02737.18 OAP54737.1 - 0.025 14.5 0.0 0.043 13.7 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF730 PF05325.11 OAP54737.1 - 0.03 14.4 0.1 0.072 13.1 0.0 1.6 2 0 0 2 2 1 0 Protein of unknown function (DUF730) Lycopene_cycl PF05834.12 OAP54737.1 - 0.066 12.3 0.3 0.12 11.4 0.3 1.6 1 1 0 1 1 1 0 Lycopene cyclase protein ApbA PF02558.16 OAP54737.1 - 0.082 12.6 0.2 0.2 11.3 0.0 1.7 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.20 OAP54737.1 - 0.11 12.5 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox_2 PF07992.14 OAP54738.1 - 1e-45 156.3 0.1 1.3e-45 155.9 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAP54738.1 - 4.6e-18 65.6 0.5 2.5e-14 53.6 0.3 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAP54738.1 - 1.2e-10 41.5 1.3 0.0033 17.1 0.0 3.6 3 1 0 4 4 4 3 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 OAP54738.1 - 1.1e-09 37.9 0.0 7.3e-09 35.3 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OAP54738.1 - 2.4e-08 33.4 0.3 0.0028 16.8 0.1 3.3 3 1 1 4 4 4 2 Lycopene cyclase protein Trp_halogenase PF04820.14 OAP54738.1 - 5.3e-08 32.2 0.1 0.24 10.2 0.0 3.3 3 0 0 3 3 3 3 Tryptophan halogenase K_oxygenase PF13434.6 OAP54738.1 - 3.1e-07 29.9 0.0 8.7e-07 28.4 0.1 1.6 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 OAP54738.1 - 1.2e-06 27.6 0.5 0.073 11.8 0.1 3.6 3 1 1 4 4 4 3 HI0933-like protein NAD_binding_8 PF13450.6 OAP54738.1 - 1.5e-06 28.3 0.0 0.0059 16.8 0.0 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 OAP54738.1 - 2.3e-06 27.7 2.1 0.34 10.9 0.1 4.1 3 1 1 4 4 4 2 FAD-NAD(P)-binding FAD_oxidored PF12831.7 OAP54738.1 - 5.4e-05 22.7 1.1 0.99 8.7 0.8 3.1 2 1 0 3 3 3 2 FAD dependent oxidoreductase TrkA_N PF02254.18 OAP54738.1 - 0.0014 18.9 0.1 0.43 10.9 0.0 3.2 2 1 0 2 2 2 1 TrkA-N domain FAD_binding_3 PF01494.19 OAP54738.1 - 0.0028 17.0 1.6 0.026 13.8 0.0 2.8 2 1 1 3 3 3 1 FAD binding domain Thi4 PF01946.17 OAP54738.1 - 0.0032 16.8 0.0 0.62 9.3 0.0 2.2 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 OAP54738.1 - 0.0051 16.0 0.0 0.43 9.6 0.1 2.4 2 0 0 2 2 2 1 FAD binding domain DUF1188 PF06690.11 OAP54738.1 - 0.013 15.1 0.0 3 7.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1188) GIDA PF01134.22 OAP54738.1 - 0.025 13.6 4.3 1.5 7.9 2.5 3.5 3 1 1 4 4 4 0 Glucose inhibited division protein A Malic_M PF03949.15 OAP54738.1 - 0.033 13.4 0.0 0.06 12.6 0.0 1.3 1 0 0 1 1 1 0 Malic enzyme, NAD binding domain Eno-Rase_NADH_b PF12242.8 OAP54738.1 - 0.072 12.9 0.1 0.48 10.2 0.0 2.1 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Caps_synth PF05704.12 OAP54739.1 - 1.8e-11 43.9 0.0 4.9e-11 42.5 0.0 1.6 1 1 0 1 1 1 1 Capsular polysaccharide synthesis protein Gly_transf_sug PF04488.15 OAP54739.1 - 9.6e-07 29.4 0.0 2.1e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif SMC_N PF02463.19 OAP54740.1 - 5.6e-57 192.7 28.1 2.9e-56 190.3 28.1 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 OAP54740.1 - 2.7e-26 92.2 0.0 2.3e-25 89.2 0.0 2.8 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 OAP54740.1 - 3.1e-19 70.3 13.4 3.1e-19 70.3 13.4 6.2 2 2 2 4 4 4 1 AAA domain AAA_15 PF13175.6 OAP54740.1 - 2.8e-14 53.6 45.0 1.8e-12 47.7 10.9 4.3 2 2 1 3 3 3 2 AAA ATPase domain AAA_21 PF13304.6 OAP54740.1 - 1.8e-13 51.0 13.3 2.9e-06 27.3 4.6 3.8 2 2 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 OAP54740.1 - 0.018 14.8 0.0 0.043 13.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Nup54_57_C PF18570.1 OAP54740.1 - 0.054 13.1 2.6 0.37 10.4 0.4 3.3 2 0 0 2 2 2 0 NUP57/Nup54 C-terminal domain UPF0184 PF03670.13 OAP54740.1 - 7.2 7.1 26.9 0.2 12.1 2.6 6.1 5 1 1 6 6 6 0 Uncharacterised protein family (UPF0184) CTP_synth_N PF06418.14 OAP54741.1 - 6.6e-116 386.2 0.1 8.9e-116 385.8 0.1 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 OAP54741.1 - 1.7e-57 194.3 0.0 2.8e-57 193.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 OAP54741.1 - 7.3e-07 29.2 0.0 2.9e-06 27.2 0.0 2.0 1 1 0 1 1 1 1 Peptidase C26 NicO PF03824.16 OAP54742.1 - 3.2e-59 200.6 13.0 1.2e-56 192.2 6.2 2.3 2 0 0 2 2 2 2 High-affinity nickel-transport protein DHHC PF01529.20 OAP54742.1 - 5.4 7.1 4.8 26 4.9 0.1 3.2 3 0 0 3 3 3 0 DHHC palmitoyltransferase Methyltransf_23 PF13489.6 OAP54743.1 - 4.7e-17 62.3 0.0 8.7e-17 61.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAP54743.1 - 2.5e-11 44.0 0.0 4.4e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAP54743.1 - 1.3e-08 35.4 0.0 3.6e-08 34.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAP54743.1 - 9.8e-08 32.7 0.0 1.7e-07 31.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAP54743.1 - 9.4e-06 25.5 0.0 7.5e-05 22.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAP54743.1 - 0.074 12.4 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family NNMT_PNMT_TEMT PF01234.17 OAP54743.1 - 0.11 11.7 0.0 0.24 10.6 0.0 1.5 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family NodS PF05401.11 OAP54743.1 - 0.2 11.2 0.0 0.33 10.5 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) MTS PF05175.14 OAP54743.1 - 0.22 11.0 0.0 6.6 6.2 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase small domain AAA_22 PF13401.6 OAP54744.1 - 4.5e-05 23.8 0.0 0.069 13.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 OAP54744.1 - 0.0028 17.0 0.0 0.0052 16.1 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_16 PF13191.6 OAP54744.1 - 0.009 16.4 0.0 5.7 7.3 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain DUF853 PF05872.12 OAP54744.1 - 0.046 12.3 0.1 0.14 10.7 0.1 1.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF853) AAA PF00004.29 OAP54744.1 - 0.12 12.8 0.4 0.35 11.3 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) CENP-B_dimeris PF09026.10 OAP54744.1 - 0.13 12.7 8.0 0.25 11.7 1.1 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Cwf_Cwc_15 PF04889.12 OAP54744.1 - 0.31 10.8 10.9 2 8.1 0.7 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Pkinase PF00069.25 OAP54745.1 - 2.4e-10 40.2 0.0 2.9e-05 23.6 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain DUF4404 PF14357.6 OAP54749.1 - 0.00059 20.4 2.1 0.073 13.7 1.8 3.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4404) FAD_binding_4 PF01565.23 OAP54750.1 - 8.3e-20 71.0 2.7 4.4e-19 68.6 2.8 2.2 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 OAP54750.1 - 1.7e-11 44.1 1.4 5.3e-11 42.4 0.1 2.2 2 0 0 2 2 2 1 Berberine and berberine like zf-Nse PF11789.8 OAP54751.1 - 4.3e-16 58.5 1.3 5.6e-16 58.1 0.1 1.8 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.15 OAP54751.1 - 2.1e-06 27.8 0.1 0.00088 19.4 0.0 2.5 1 1 1 2 2 2 2 U-box domain zf-RING_UBOX PF13445.6 OAP54751.1 - 0.029 14.4 0.2 0.081 13.0 0.0 1.8 2 0 0 2 2 2 0 RING-type zinc-finger PorB PF11565.8 OAP54751.1 - 0.11 12.9 1.8 0.51 10.8 0.0 2.5 2 0 0 2 2 2 0 Alpha helical Porin B zf-C3HC4_2 PF13923.6 OAP54751.1 - 0.22 11.4 0.4 0.58 10.1 0.0 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) NPC1_N PF16414.5 OAP54752.1 - 5.7e-84 281.5 9.5 7.9e-84 281.0 9.5 1.2 1 0 0 1 1 1 1 Niemann-Pick C1 N terminus Patched PF02460.18 OAP54752.1 - 1.4e-72 245.0 8.3 1.5e-71 241.6 8.3 2.1 1 1 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 OAP54752.1 - 2.2e-51 173.7 6.6 2.2e-51 173.7 6.6 3.0 2 1 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.15 OAP54752.1 - 5.7e-07 28.8 24.1 0.00016 20.7 8.5 2.4 2 0 0 2 2 2 2 MMPL family Folate_rec PF03024.14 OAP54752.1 - 0.01 15.7 2.9 0.02 14.8 2.9 1.4 1 0 0 1 1 1 0 Folate receptor family CaM_bdg_C0 PF10562.9 OAP54752.1 - 0.053 13.6 0.3 0.11 12.5 0.3 1.5 1 0 0 1 1 1 0 Calmodulin-binding domain C0 of NMDA receptor NR1 subunit ACR_tran PF00873.19 OAP54752.1 - 8.5 3.9 20.7 0.047 11.4 12.1 1.5 2 0 0 2 2 2 0 AcrB/AcrD/AcrF family DUF2433 PF10360.9 OAP54753.1 - 3.4e-46 156.4 0.0 6.1e-46 155.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) Metallophos PF00149.28 OAP54753.1 - 7.1e-05 23.4 0.0 0.00022 21.8 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OAP54753.1 - 0.0037 17.5 0.0 0.019 15.2 0.0 2.2 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain TFIIA PF03153.13 OAP54753.1 - 0.92 9.4 10.6 0.072 13.1 5.8 1.6 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit PAP1 PF08601.10 OAP54754.1 - 2e-104 350.3 6.9 2e-104 350.3 6.9 3.0 3 1 0 3 3 3 2 Transcription factor PAP1 bZIP_1 PF00170.21 OAP54754.1 - 1.9e-08 34.3 10.2 4.1e-08 33.2 10.2 1.6 1 0 0 1 1 1 1 bZIP transcription factor ERM PF00769.19 OAP54754.1 - 0.0016 18.3 1.3 0.0016 18.3 1.3 1.9 2 0 0 2 2 2 1 Ezrin/radixin/moesin family SHE3 PF17078.5 OAP54754.1 - 0.005 16.6 4.3 0.01 15.5 4.3 1.4 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 IL11 PF07400.11 OAP54754.1 - 0.027 14.1 0.5 0.052 13.2 0.5 1.3 1 0 0 1 1 1 0 Interleukin 11 DUF812 PF05667.11 OAP54754.1 - 0.032 13.1 2.1 0.048 12.6 2.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) bZIP_Maf PF03131.17 OAP54754.1 - 0.068 13.7 8.4 0.17 12.4 8.4 1.7 1 0 0 1 1 1 0 bZIP Maf transcription factor bZIP_2 PF07716.15 OAP54754.1 - 0.091 12.9 14.0 0.29 11.3 12.6 2.4 1 1 1 2 2 2 0 Basic region leucine zipper SlyX PF04102.12 OAP54754.1 - 0.13 12.9 0.3 0.38 11.4 0.3 1.9 1 0 0 1 1 1 0 SlyX JIP_LZII PF16471.5 OAP54754.1 - 0.9 9.8 4.3 22 5.3 2.6 2.5 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II CDC45 PF02724.14 OAP54754.1 - 8.3 4.6 7.9 14 3.9 7.9 1.2 1 0 0 1 1 1 0 CDC45-like protein Tudor_3 PF18115.1 OAP54755.1 - 8.3e-06 25.6 0.0 1.5e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain TUDOR PF00567.24 OAP54755.1 - 0.00027 21.0 0.0 0.0045 17.0 0.0 2.1 2 0 0 2 2 2 1 Tudor domain LBR_tudor PF09465.10 OAP54755.1 - 0.0008 19.2 0.2 0.0021 17.8 0.0 1.8 2 0 0 2 2 2 1 Lamin-B receptor of TUDOR domain Fis1_TPR_C PF14853.6 OAP54755.1 - 0.037 14.1 0.6 0.069 13.2 0.6 1.4 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat Tudor_2 PF18104.1 OAP54755.1 - 0.044 13.5 0.0 0.12 12.0 0.0 1.8 1 0 0 1 1 1 0 Jumonji domain-containing protein 2A Tudor domain DUF4537 PF15057.6 OAP54755.1 - 0.084 12.9 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4537) DUF2730 PF10805.8 OAP54755.1 - 0.093 12.8 0.4 0.18 11.9 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) Tmemb_170 PF10190.9 OAP54756.1 - 3.8e-16 59.4 12.9 9.6e-15 54.9 4.4 2.1 2 0 0 2 2 2 2 Putative transmembrane protein 170 Acyl-CoA_dh_N PF02771.16 OAP54756.1 - 0.03 15.0 0.0 0.058 14.1 0.0 1.4 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, N-terminal domain PRA1 PF03208.19 OAP54756.1 - 0.067 12.8 2.7 0.12 12.0 2.7 1.5 1 1 0 1 1 1 0 PRA1 family protein COesterase PF00135.28 OAP54757.1 - 7.4e-81 272.5 0.0 4.8e-73 246.8 0.1 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 OAP54757.1 - 1.3e-09 38.2 0.0 2.4e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Retrotran_gag_2 PF14223.6 OAP54758.1 - 1.6e-13 50.5 0.1 1.5e-12 47.3 0.2 2.1 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type FUSC PF04632.12 OAP54758.1 - 1.7 7.1 3.0 2.7 6.4 3.0 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family adh_short_C2 PF13561.6 OAP54759.1 - 1.6e-61 207.8 1.3 1.9e-61 207.6 1.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP54759.1 - 2.3e-42 144.7 0.4 2.8e-42 144.4 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAP54759.1 - 1.7e-14 54.1 0.3 2.6e-14 53.5 0.3 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAP54759.1 - 0.0048 16.4 0.1 0.14 11.6 0.0 2.2 1 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family S4 PF01479.25 OAP54759.1 - 0.039 13.7 0.0 0.1 12.4 0.0 1.8 1 0 0 1 1 1 0 S4 domain Sacchrp_dh_NADP PF03435.18 OAP54759.1 - 0.1 12.8 0.1 0.16 12.2 0.1 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain GST_N_3 PF13417.6 OAP54760.1 - 2.4e-10 40.6 0.1 5.7e-10 39.5 0.1 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OAP54760.1 - 7e-10 39.1 0.0 1.1e-09 38.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAP54760.1 - 5.6e-05 23.1 0.0 0.00011 22.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain PAS_4 PF08448.10 OAP54760.1 - 0.057 13.7 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 PAS fold Glyco_hydro_31 PF01055.26 OAP54761.1 - 6.6e-108 361.7 1.4 9.2e-108 361.2 1.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 OAP54761.1 - 1.9e-17 63.3 0.2 3.4e-16 59.3 0.1 3.1 4 0 0 4 4 4 1 Galactose mutarotase-like Sugar_tr PF00083.24 OAP54762.1 - 4.8e-73 246.5 24.1 5.6e-73 246.3 24.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP54762.1 - 1.2e-19 70.4 29.1 1.2e-19 70.4 29.1 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.6 OAP54762.1 - 1.7e-05 23.6 19.1 0.0062 15.1 1.9 2.5 2 1 1 3 3 3 3 MFS/sugar transport protein MFS_1_like PF12832.7 OAP54762.1 - 0.00058 18.8 5.0 0.00058 18.8 5.0 1.8 2 0 0 2 2 2 1 MFS_1 like family Phage_holin_2_4 PF16082.5 OAP54762.1 - 0.15 11.8 3.4 0.21 11.4 0.9 2.4 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like adh_short PF00106.25 OAP54763.1 - 2.5e-44 151.1 0.5 4.4e-44 150.3 0.5 1.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP54763.1 - 2.5e-40 138.5 0.4 8.8e-40 136.7 0.4 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP54763.1 - 5.2e-10 39.5 1.0 2.5e-09 37.3 0.1 2.0 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 OAP54763.1 - 0.00091 18.4 0.1 0.0015 17.7 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.20 OAP54763.1 - 0.0026 17.8 0.0 0.0051 16.9 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ADH_zinc_N PF00107.26 OAP54763.1 - 0.0076 16.2 0.0 0.016 15.2 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase F420_oxidored PF03807.17 OAP54763.1 - 0.013 16.0 0.1 0.033 14.7 0.1 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Glu_dehyd_C PF16912.5 OAP54763.1 - 0.017 14.6 0.0 0.035 13.6 0.0 1.5 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus DUF1776 PF08643.10 OAP54763.1 - 0.019 14.4 0.1 0.045 13.1 0.1 1.6 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) 3HCDH_N PF02737.18 OAP54763.1 - 0.038 13.9 0.1 0.18 11.7 0.1 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 OAP54763.1 - 0.046 13.4 0.1 0.45 10.1 0.0 2.2 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Epimerase PF01370.21 OAP54763.1 - 0.047 13.1 0.7 0.25 10.8 0.7 2.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Dak1 PF02733.17 OAP54763.1 - 0.057 12.3 0.1 0.84 8.5 0.0 2.1 2 0 0 2 2 2 0 Dak1 domain tRNA_m1G_MT PF01746.21 OAP54763.1 - 0.084 12.6 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 tRNA (Guanine-1)-methyltransferase GDP_Man_Dehyd PF16363.5 OAP54763.1 - 0.097 12.1 0.1 0.31 10.4 0.0 1.8 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase MFS_1 PF07690.16 OAP54764.1 - 1.9e-39 135.6 61.6 4.2e-39 134.5 57.6 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 OAP54764.1 - 2.6e-09 36.1 25.3 2.6e-09 36.1 25.3 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) FA_desaturase PF00487.24 OAP54764.1 - 0.066 13.0 7.6 0.022 14.6 3.4 2.4 1 1 1 2 2 2 0 Fatty acid desaturase adh_short_C2 PF13561.6 OAP54765.1 - 4.6e-46 157.3 0.0 5e-45 153.9 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP54765.1 - 5.3e-35 120.7 0.0 1.3e-33 116.1 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAP54765.1 - 5.5e-09 36.2 0.0 9e-09 35.5 0.0 1.4 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.10 OAP54765.1 - 0.0015 18.0 0.1 0.0023 17.4 0.1 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) PALP PF00291.25 OAP54765.1 - 0.034 13.6 0.0 0.045 13.2 0.0 1.1 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme Apolipoprotein PF01442.18 OAP54766.1 - 0.00022 21.2 4.1 0.0004 20.3 2.9 2.0 2 0 0 2 2 2 1 Apolipoprotein A1/A4/E domain Spc7 PF08317.11 OAP54766.1 - 0.00046 19.2 8.2 0.00084 18.3 7.7 1.7 1 1 0 1 1 1 1 Spc7 kinetochore protein TACC_C PF05010.14 OAP54766.1 - 0.0014 18.4 4.3 0.0026 17.6 0.2 2.3 1 1 1 2 2 2 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal MIP-T3_C PF17749.1 OAP54766.1 - 0.0017 18.4 4.4 0.087 12.8 0.2 2.5 1 1 1 2 2 2 2 Microtubule-binding protein MIP-T3 C-terminal region TPR_MLP1_2 PF07926.12 OAP54766.1 - 0.006 16.7 6.1 0.11 12.5 5.4 2.8 1 1 1 2 2 2 1 TPR/MLP1/MLP2-like protein DUF4407 PF14362.6 OAP54766.1 - 0.015 14.7 2.1 0.024 14.0 2.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Baculo_PEP_C PF04513.12 OAP54766.1 - 0.017 15.2 3.2 0.042 13.9 2.0 2.2 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Rab5-bind PF09311.11 OAP54766.1 - 0.025 14.0 6.2 0.055 12.8 6.2 1.5 1 0 0 1 1 1 0 Rabaptin-like protein IFT57 PF10498.9 OAP54766.1 - 0.031 13.3 4.5 0.076 12.0 0.3 2.2 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 HIP1_clath_bdg PF16515.5 OAP54766.1 - 0.031 14.9 9.9 0.04 14.5 6.7 2.8 2 1 1 3 3 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF948 PF06103.11 OAP54766.1 - 0.04 14.2 2.6 56 4.1 3.5 3.9 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Golgin_A5 PF09787.9 OAP54766.1 - 0.04 13.4 4.2 0.97 8.8 0.2 2.2 1 1 1 2 2 2 0 Golgin subfamily A member 5 AAA_13 PF13166.6 OAP54766.1 - 0.059 12.0 2.8 0.086 11.5 2.8 1.1 1 0 0 1 1 1 0 AAA domain Fez1 PF06818.15 OAP54766.1 - 0.064 13.7 3.8 0.12 12.9 3.8 1.4 1 0 0 1 1 1 0 Fez1 EzrA PF06160.12 OAP54766.1 - 0.095 10.9 4.7 0.55 8.3 3.0 2.0 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA Exonuc_VII_L PF02601.15 OAP54766.1 - 0.13 11.8 1.9 0.28 10.7 1.9 1.7 1 0 0 1 1 1 0 Exonuclease VII, large subunit Syntaxin-6_N PF09177.11 OAP54766.1 - 0.13 12.8 11.2 3.3 8.3 0.4 3.6 1 1 1 3 3 3 0 Syntaxin 6, N-terminal HMMR_C PF15908.5 OAP54766.1 - 0.17 12.2 2.3 0.33 11.2 2.3 1.4 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor C-terminal Filament PF00038.21 OAP54766.1 - 0.18 11.4 6.0 1.7 8.2 0.5 2.2 1 1 0 2 2 2 0 Intermediate filament protein NPV_P10 PF05531.12 OAP54766.1 - 0.23 12.0 4.3 9.6 6.8 0.1 3.7 2 1 2 4 4 3 0 Nucleopolyhedrovirus P10 protein USP8_interact PF08941.10 OAP54766.1 - 0.33 10.8 4.0 0.97 9.2 0.5 3.0 4 0 0 4 4 3 0 USP8 interacting Sec8_exocyst PF04048.14 OAP54766.1 - 0.34 10.8 3.9 1.7 8.5 0.6 2.6 1 1 0 2 2 2 0 Sec8 exocyst complex component specific domain Snapin_Pallidin PF14712.6 OAP54766.1 - 0.38 11.2 4.6 2.4 8.6 2.7 2.9 3 0 0 3 3 2 0 Snapin/Pallidin DUF3450 PF11932.8 OAP54766.1 - 0.49 9.6 5.4 1.5 8.1 5.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Prefoldin_2 PF01920.20 OAP54766.1 - 0.5 10.3 4.2 1.9 8.5 0.2 2.7 3 0 0 3 3 2 0 Prefoldin subunit DUF4744 PF15918.5 OAP54766.1 - 0.61 11.0 8.4 1.1 10.1 0.1 4.4 3 1 1 4 4 4 0 Domain of unknown function (DUF4744) YtxH PF12732.7 OAP54766.1 - 0.81 10.3 4.8 4 8.0 0.5 3.5 3 1 1 4 4 2 0 YtxH-like protein Fib_alpha PF08702.10 OAP54766.1 - 0.88 9.7 6.1 5 7.3 1.1 2.9 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family TMF_DNA_bd PF12329.8 OAP54766.1 - 0.9 9.6 7.5 3.7 7.6 0.1 3.4 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding GCP_C_terminal PF04130.13 OAP54766.1 - 0.91 8.9 7.0 2.3 7.6 1.8 2.2 1 1 1 2 2 2 0 Gamma tubulin complex component C-terminal ZapB PF06005.12 OAP54766.1 - 1.1 9.7 8.3 8.3 6.9 0.7 3.3 4 0 0 4 4 2 0 Cell division protein ZapB FlaC_arch PF05377.11 OAP54766.1 - 1.6 9.2 4.7 1.2e+02 3.2 0.1 4.4 4 1 1 5 5 5 0 Flagella accessory protein C (FlaC) DUF2203 PF09969.9 OAP54766.1 - 2.1 9.1 3.8 20 5.9 2.3 2.7 2 1 1 3 3 2 0 Uncharacterized conserved protein (DUF2203) CorA PF01544.18 OAP54766.1 - 2.2 7.5 7.4 0.99 8.7 4.3 1.9 2 1 0 2 2 2 0 CorA-like Mg2+ transporter protein Bap31_Bap29_C PF18035.1 OAP54766.1 - 2.4 8.2 5.4 0.76 9.8 1.2 2.3 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain DUF2730 PF10805.8 OAP54766.1 - 2.5 8.2 5.0 5 7.3 0.2 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2730) DUF1664 PF07889.12 OAP54766.1 - 3.7 7.6 7.0 12 5.9 0.3 3.2 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) TMPIT PF07851.13 OAP54766.1 - 4.4 6.5 5.2 30 3.7 4.9 2.1 1 1 1 2 2 2 0 TMPIT-like protein TolA_bind_tri PF16331.5 OAP54766.1 - 6.6 6.9 7.2 2 8.5 0.6 3.3 4 0 0 4 4 3 0 TolA binding protein trimerisation MerR-DNA-bind PF09278.11 OAP54766.1 - 7.9 7.1 11.0 2 9.0 0.0 4.2 4 1 1 5 5 4 0 MerR, DNA binding zf-C4H2 PF10146.9 OAP54766.1 - 7.9 6.7 10.2 71 3.6 10.1 2.5 1 1 0 1 1 1 0 Zinc finger-containing protein Serine_rich PF08824.10 OAP54766.1 - 9.5 6.2 13.3 0.59 10.1 6.5 2.5 2 1 0 2 2 1 0 Serine rich protein interaction domain Fungal_trans PF04082.18 OAP54767.1 - 7.6e-15 54.7 0.1 1.3e-14 53.9 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP54767.1 - 2e-08 34.2 10.0 3.6e-08 33.4 10.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF913 PF06025.12 OAP54767.1 - 0.11 11.5 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Pectate_lyase_3 PF12708.7 OAP54769.1 - 0.0029 17.5 1.0 0.0029 17.5 1.0 3.1 2 1 2 4 4 4 1 Pectate lyase superfamily protein DUF1373 PF07117.11 OAP54769.1 - 0.011 15.7 1.5 0.023 14.7 1.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1373) DPPIV_N PF00930.21 OAP54771.1 - 8.7e-103 343.8 0.0 1.2e-102 343.3 0.0 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 OAP54771.1 - 5e-56 189.5 0.9 1.1e-55 188.4 0.8 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 OAP54771.1 - 2.8e-06 27.1 1.4 3.3e-05 23.6 0.6 2.2 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.18 OAP54771.1 - 0.0043 16.6 0.0 0.014 14.9 0.0 1.7 1 1 0 1 1 1 1 Dienelactone hydrolase family Esterase PF00756.20 OAP54771.1 - 0.0052 16.5 0.1 0.013 15.2 0.1 1.6 1 1 0 1 1 1 1 Putative esterase Abhydrolase_1 PF00561.20 OAP54771.1 - 0.018 14.7 0.5 0.089 12.4 0.1 2.3 2 1 1 3 3 3 0 alpha/beta hydrolase fold Virul_fac_BrkB PF03631.15 OAP54772.1 - 0.0029 17.3 0.1 0.004 16.8 0.1 1.2 1 0 0 1 1 1 1 Virulence factor BrkB Helo_like_N PF17111.5 OAP54773.1 - 2.2e-12 46.8 6.0 2.2e-12 46.8 6.0 1.8 2 0 0 2 2 2 1 Fungal N-terminal domain of STAND proteins DUF1664 PF07889.12 OAP54773.1 - 0.04 14.0 8.3 0.4 10.7 3.5 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) Ribosomal_60s PF00428.19 OAP54773.1 - 0.067 13.8 22.7 1.1 9.9 13.9 4.0 3 0 0 3 3 3 0 60s Acidic ribosomal protein Presenilin PF01080.17 OAP54773.1 - 0.14 10.8 3.4 0.23 10.2 3.4 1.5 1 0 0 1 1 1 0 Presenilin Sec34 PF04136.15 OAP54773.1 - 0.27 11.1 5.0 0.47 10.3 1.4 2.6 2 1 1 3 3 3 0 Sec34-like family KAR PF15222.6 OAP54773.1 - 0.72 10.2 8.7 1.5 9.1 0.9 2.6 1 1 1 2 2 2 0 Kidney androgen-regulated NPV_P10 PF05531.12 OAP54773.1 - 1.3 9.6 7.5 18 5.9 4.4 2.8 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Radial_spoke PF04712.12 OAP54773.1 - 2.1 7.2 17.9 0.84 8.5 15.1 1.7 1 1 1 2 2 2 0 Radial spokehead-like protein Voltage_CLC PF00654.20 OAP54775.1 - 6.8e-89 298.6 23.7 6.8e-89 298.6 23.7 1.8 2 0 0 2 2 2 1 Voltage gated chloride channel Lipase_GDSL_2 PF13472.6 OAP54776.1 - 5.8e-28 98.5 0.0 1.3e-27 97.4 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 OAP54776.1 - 5.5e-19 68.9 0.0 7.3e-19 68.5 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase eIF-5_eIF-2B PF01873.17 OAP54777.1 - 1.9e-38 130.9 0.0 3.5e-38 130.1 0.0 1.5 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.18 OAP54777.1 - 3.7e-20 71.8 0.1 3.7e-20 71.8 0.1 2.2 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon HK PF02110.15 OAP54778.1 - 7e-78 261.4 0.4 1.3e-77 260.5 0.4 1.4 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.17 OAP54778.1 - 2.4e-59 199.7 2.5 2.4e-59 199.7 2.5 1.6 2 0 0 2 2 2 1 Thiamine monophosphate synthase Carb_kinase PF01256.17 OAP54778.1 - 0.00099 18.6 0.2 0.0017 17.8 0.2 1.5 1 1 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.12 OAP54778.1 - 0.0037 16.7 0.1 0.01 15.3 0.0 1.8 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase IMPDH PF00478.25 OAP54778.1 - 0.38 9.7 7.1 0.9 8.5 7.1 1.6 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain ACPS PF01648.20 OAP54779.1 - 6e-09 36.0 0.0 1.8e-08 34.5 0.1 1.8 2 1 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily SNO PF01174.19 OAP54780.1 - 3.6e-55 186.7 0.0 6.4e-45 153.3 0.0 2.1 2 0 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.14 OAP54780.1 - 3e-09 36.7 0.0 3.7e-08 33.2 0.0 2.0 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.28 OAP54780.1 - 0.00064 19.5 0.0 0.0037 17.0 0.0 1.9 1 1 0 1 1 1 1 Glutamine amidotransferase class-I DJ-1_PfpI PF01965.24 OAP54780.1 - 0.0015 18.3 0.0 0.0059 16.4 0.0 1.8 2 0 0 2 2 2 1 DJ-1/PfpI family Peptidase_S51 PF03575.17 OAP54780.1 - 0.036 13.7 0.0 0.053 13.2 0.0 1.2 1 0 0 1 1 1 0 Peptidase family S51 RRM_1 PF00076.22 OAP54781.1 - 1.3e-15 57.0 0.0 2e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TauD PF02668.16 OAP54782.1 - 7.1e-46 157.2 0.3 1e-45 156.6 0.3 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.16 OAP54783.1 - 7.5e-32 110.6 23.7 7.5e-32 110.6 23.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 OAP54783.1 - 4.2e-06 25.9 6.3 2.5e-05 23.3 0.6 3.2 2 1 1 3 3 3 1 MFS_1 like family Gram_pos_anchor PF00746.21 OAP54783.1 - 9.2 6.3 6.0 28 4.8 1.1 2.7 2 0 0 2 2 2 0 LPXTG cell wall anchor motif MFS_1 PF07690.16 OAP54784.1 - 5.4e-34 117.7 25.4 8.4e-34 117.0 24.3 1.7 1 1 0 2 2 2 1 Major Facilitator Superfamily VIT1 PF01988.19 OAP54784.1 - 0.013 15.4 0.7 0.028 14.3 0.7 1.6 1 0 0 1 1 1 0 VIT family DUF3894 PF13033.6 OAP54784.1 - 1.8 8.8 10.5 1.5 9.0 0.2 4.4 4 0 0 4 4 4 0 Protein of unknown function (DUF3894) Lipoprotein_20 PF13942.6 OAP54785.1 - 0.027 14.4 2.3 0.052 13.5 2.3 1.3 1 0 0 1 1 1 0 YfhG lipoprotein DUF3584 PF12128.8 OAP54785.1 - 0.2 9.1 7.3 0.32 8.4 7.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Nup88 PF10168.9 OAP54785.1 - 0.3 8.8 5.0 3.2 5.5 0.0 2.2 2 0 0 2 2 2 0 Nuclear pore component Nup54 PF13874.6 OAP54785.1 - 0.43 10.7 6.5 0.74 9.9 5.5 1.9 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 ATG16 PF08614.11 OAP54785.1 - 0.45 10.7 9.5 0.079 13.2 4.5 2.1 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) V_ATPase_I PF01496.19 OAP54785.1 - 0.54 8.1 0.9 0.77 7.6 0.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SlyX PF04102.12 OAP54785.1 - 8.4 7.1 8.9 1.2 9.9 1.4 3.2 3 0 0 3 3 3 0 SlyX DNA_pol_E_B PF04042.16 OAP54786.1 - 5.2e-49 166.5 0.0 7.4e-49 166.0 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B SHNi-TPR PF10516.9 OAP54787.1 - 2.3e-13 49.4 0.3 2.3e-13 49.4 0.3 2.0 2 0 0 2 2 2 1 SHNi-TPR TPR_16 PF13432.6 OAP54787.1 - 0.14 12.8 2.7 0.19 12.4 1.3 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 OAP54787.1 - 1.9 8.9 14.9 2 8.8 2.8 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 OAP54787.1 - 2.3 8.2 6.3 40 4.3 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Ribonuc_L-PSP PF01042.21 OAP54788.1 - 1.9e-18 66.6 0.0 2.2e-18 66.4 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Fungal_trans PF04082.18 OAP54789.1 - 5e-23 81.5 0.2 7.1e-23 81.0 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP54789.1 - 3.7e-07 30.1 11.0 3.7e-07 30.1 11.0 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CLZ PF16526.5 OAP54789.1 - 0.11 12.9 0.0 0.24 11.8 0.0 1.5 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels PSI PF01437.25 OAP54789.1 - 0.13 12.8 3.3 0.3 11.6 3.3 1.6 1 0 0 1 1 1 0 Plexin repeat Arylesterase PF01731.20 OAP54790.1 - 2.8e-06 27.4 0.1 0.00014 22.0 0.0 2.8 2 1 0 2 2 2 1 Arylesterase EIIBC-GUT_N PF03612.14 OAP54790.1 - 0.002 17.9 4.2 2.8 7.6 0.0 2.3 2 0 0 2 2 2 2 Sorbitol phosphotransferase enzyme II N-terminus NHL PF01436.21 OAP54790.1 - 0.012 15.6 0.2 0.045 13.8 0.1 2.1 2 0 0 2 2 2 0 NHL repeat Misat_Tub_SegII PF10644.9 OAP54790.1 - 0.013 15.8 0.6 0.026 14.9 0.6 1.4 1 0 0 1 1 1 0 Misato Segment II tubulin-like domain PQQ_3 PF13570.6 OAP54790.1 - 0.014 15.8 0.0 0.35 11.4 0.0 2.4 2 0 0 2 2 2 0 PQQ-like domain RNA_pol_Rbc25 PF08292.12 OAP54790.1 - 0.042 14.1 3.4 0.084 13.1 3.4 1.4 1 0 0 1 1 1 0 RNA polymerase III subunit Rpc25 SUFU_C PF12470.8 OAP54790.1 - 0.078 13.0 3.0 0.12 12.4 3.0 1.2 1 0 0 1 1 1 0 Suppressor of Fused Gli/Ci N terminal binding domain TMEM214 PF10151.9 OAP54790.1 - 1.1 7.6 7.3 1.5 7.2 7.3 1.1 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator SR-25 PF10500.9 OAP54790.1 - 1.7 8.2 19.1 2.3 7.8 19.1 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein HA2 PF04408.23 OAP54790.1 - 1.9 8.8 6.0 6 7.2 6.2 1.7 2 0 0 2 2 1 0 Helicase associated domain (HA2) AP3D1 PF06375.11 OAP54790.1 - 2 8.6 17.8 3.1 8.0 17.8 1.2 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 DUF4887 PF16228.5 OAP54790.1 - 2.2 8.5 20.4 3.2 7.9 20.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4887) Connexin PF00029.19 OAP54790.1 - 9.8 5.9 9.1 14 5.3 9.1 1.2 1 0 0 1 1 1 0 Connexin COesterase PF00135.28 OAP54791.1 - 7.6e-59 199.9 0.0 9.5e-59 199.6 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAP54791.1 - 1.4e-08 34.9 0.3 0.00049 20.0 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OAP54791.1 - 0.0064 16.0 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family MFS_1 PF07690.16 OAP54792.1 - 8.5e-22 77.5 14.3 8.5e-22 77.5 14.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 OAP54792.1 - 0.00047 18.7 1.9 0.00047 18.7 1.9 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DAO PF01266.24 OAP54793.1 - 7e-50 170.6 0.0 1e-49 170.1 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 OAP54793.1 - 3.1e-45 153.1 0.0 6.2e-45 152.1 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 OAP54793.1 - 2.4e-08 33.5 2.0 2.9e-07 29.9 2.0 2.1 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 OAP54793.1 - 7.7e-05 22.2 0.0 0.00013 21.4 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAP54793.1 - 0.00045 19.5 0.1 0.0009 18.6 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAP54793.1 - 0.0028 17.9 0.1 0.02 15.1 0.2 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 OAP54793.1 - 0.017 14.3 0.1 0.099 11.7 0.1 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 OAP54793.1 - 0.021 14.1 0.0 0.087 12.1 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 OAP54793.1 - 0.025 14.5 0.1 0.044 13.7 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.14 OAP54793.1 - 0.028 13.1 0.2 0.045 12.5 0.2 1.3 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.27 OAP54793.1 - 0.055 14.0 0.2 0.16 12.6 0.2 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MIP PF00230.20 OAP54794.1 - 2.3e-55 187.8 6.8 2.9e-55 187.4 6.8 1.1 1 0 0 1 1 1 1 Major intrinsic protein FGGY_C PF02782.16 OAP54795.1 - 5.6e-74 248.2 1.2 1.1e-73 247.2 0.5 1.9 3 0 0 3 3 3 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 OAP54795.1 - 1e-66 225.0 0.0 1.4e-66 224.6 0.0 1.1 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FAD_binding_3 PF01494.19 OAP54796.1 - 4.4e-24 85.4 0.6 7.7e-24 84.6 0.6 1.3 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 OAP54796.1 - 1.5e-10 40.8 2.3 3.7e-05 23.1 0.2 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAP54796.1 - 3.1e-07 30.3 5.1 3.2e-06 27.0 2.4 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 OAP54796.1 - 6.8e-07 28.5 6.1 0.00026 20.0 0.3 2.7 3 0 0 3 3 3 2 Tryptophan halogenase NAD_binding_8 PF13450.6 OAP54796.1 - 2.5e-06 27.6 1.6 5.8e-06 26.4 1.6 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 OAP54796.1 - 5.6e-06 25.7 3.4 1.1e-05 24.7 3.4 1.5 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 OAP54796.1 - 0.00012 21.2 6.3 0.0046 16.1 0.1 2.4 2 1 0 2 2 2 2 Lycopene cyclase protein Pyr_redox PF00070.27 OAP54796.1 - 0.0018 18.8 0.9 0.011 16.3 0.2 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAP54796.1 - 0.0021 16.9 2.3 0.0032 16.2 1.0 1.8 2 0 0 2 2 2 1 HI0933-like protein Amino_oxidase PF01593.24 OAP54796.1 - 0.0031 16.9 2.7 0.29 10.4 0.4 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Thi4 PF01946.17 OAP54796.1 - 0.0087 15.3 0.5 0.016 14.5 0.5 1.4 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 OAP54796.1 - 0.013 14.6 2.9 0.022 13.8 2.9 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_oxidored PF12831.7 OAP54796.1 - 0.022 14.1 3.7 0.027 13.8 3.4 1.5 1 1 0 1 1 1 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 OAP54796.1 - 0.03 13.6 0.4 0.047 13.0 0.4 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 OAP54796.1 - 0.065 13.1 0.3 0.11 12.4 0.3 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 OAP54796.1 - 0.07 12.4 0.4 0.14 11.4 0.4 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 OAP54796.1 - 0.14 11.2 0.0 1.4 7.9 0.0 2.3 2 1 0 2 2 2 0 Squalene epoxidase NAD_binding_9 PF13454.6 OAP54796.1 - 0.17 11.9 3.0 7.9 6.4 0.3 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding DWNN PF08783.11 OAP54797.1 - 3.5e-22 78.5 0.1 8.6e-22 77.2 0.1 1.7 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.6 OAP54797.1 - 8.7e-08 31.8 8.0 8.7e-08 31.8 8.0 1.9 2 0 0 2 2 1 1 Zinc knuckle U-box PF04564.15 OAP54797.1 - 2.9e-06 27.4 0.0 1.2e-05 25.4 0.0 2.1 2 0 0 2 2 2 1 U-box domain zf-CCHC PF00098.23 OAP54797.1 - 0.00043 20.2 1.6 0.00082 19.3 1.6 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 OAP54797.1 - 0.011 15.7 0.7 0.035 14.1 0.7 1.8 1 0 0 1 1 1 0 Zinc knuckle zf-RING_UBOX PF13445.6 OAP54797.1 - 0.041 13.9 6.2 0.087 12.9 6.2 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-CCHC_5 PF14787.6 OAP54797.1 - 0.074 12.8 0.9 0.24 11.1 0.9 1.8 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-RING_4 PF14570.6 OAP54797.1 - 0.31 10.9 4.8 0.7 9.7 4.8 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4 PF00097.25 OAP54797.1 - 0.6 10.0 7.9 1.4 8.8 7.9 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OAP54797.1 - 0.6 10.3 7.9 1.5 9.0 7.9 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 OAP54797.1 - 1.2 9.1 14.8 0.035 14.0 8.2 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OAP54797.1 - 3 7.8 10.9 1.7 8.6 4.7 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) RabGAP-TBC PF00566.18 OAP54798.1 - 8.8e-49 166.1 0.0 2.8e-47 161.1 0.0 2.1 2 0 0 2 2 2 2 Rab-GTPase-TBC domain RRM_1 PF00076.22 OAP54799.1 - 1e-34 118.1 0.1 1.9e-16 59.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OAP54799.1 - 1.5e-12 47.4 0.1 0.0001 22.3 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif RRM_3 PF08777.11 OAP54799.1 - 0.029 14.4 0.0 1.2 9.2 0.0 2.4 2 0 0 2 2 2 0 RNA binding motif TRP PF06011.12 OAP54800.1 - 5.7e-141 470.1 19.3 7.2e-141 469.8 19.3 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 OAP54800.1 - 5.1e-37 127.3 3.6 8.1e-37 126.7 3.6 1.3 1 0 0 1 1 1 1 ML-like domain E1_DerP2_DerF2 PF02221.15 OAP54800.1 - 7e-06 26.5 0.6 1.3e-05 25.7 0.6 1.4 1 0 0 1 1 1 1 ML domain DUF1153 PF06627.11 OAP54800.1 - 0.02 15.0 0.1 6.4 7.0 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1153) DUF1218 PF06749.12 OAP54800.1 - 0.82 10.2 13.4 3 8.4 0.3 4.2 3 1 0 3 3 3 0 Protein of unknown function (DUF1218) Glyco_hydro_cc PF11790.8 OAP54801.1 - 2.4e-60 204.1 0.0 2.8e-60 203.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core FAD_binding_6 PF00970.24 OAP54802.1 - 1.7e-30 105.3 0.0 2.7e-30 104.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 OAP54802.1 - 4.5e-27 94.9 0.0 6.8e-27 94.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 OAP54802.1 - 8e-05 22.8 0.0 0.0046 17.1 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 OAP54802.1 - 0.026 14.7 0.0 0.048 13.9 0.0 1.4 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain DUF3605 PF12239.8 OAP54803.1 - 1.5e-58 197.5 0.1 1.7e-58 197.3 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) tRNA-synt_1d PF00750.19 OAP54805.1 - 1.8e-92 310.0 9.3 9e-92 307.7 9.3 1.8 1 1 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 OAP54805.1 - 2.9e-31 108.1 0.6 6.9e-31 106.9 0.6 1.7 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 OAP54805.1 - 3.3e-08 34.0 2.3 4.5e-08 33.6 0.1 2.5 3 0 0 3 3 3 1 Arginyl tRNA synthetase N terminal domain tRNA-synt_1e PF01406.19 OAP54805.1 - 0.037 13.4 0.4 0.091 12.1 0.0 1.8 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain Ank_2 PF12796.7 OAP54807.1 - 1.1e-108 356.0 14.0 1.1e-17 64.4 0.1 5.9 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAP54807.1 - 1.2e-67 223.4 0.8 6e-11 42.7 0.0 6.3 1 1 6 7 7 7 7 Ankyrin repeats (many copies) Ank PF00023.30 OAP54807.1 - 2.6e-46 154.1 8.7 0.00025 21.3 0.0 9.2 8 0 0 8 8 8 8 Ankyrin repeat Ank_3 PF13606.6 OAP54807.1 - 6.2e-37 121.4 0.1 0.0059 17.0 0.0 10.1 10 0 0 10 10 10 8 Ankyrin repeat Ank_5 PF13857.6 OAP54807.1 - 2.7e-31 107.2 2.2 8e-06 26.0 0.1 8.8 2 1 7 9 9 9 8 Ankyrin repeats (many copies) NACHT PF05729.12 OAP54807.1 - 0.00013 21.9 0.0 0.00033 20.6 0.0 1.7 1 0 0 1 1 1 1 NACHT domain IQCJ-SCHIP1 PF15157.6 OAP54807.1 - 0.0092 15.8 0.1 0.02 14.8 0.1 1.5 1 0 0 1 1 1 1 Fusion protein IQCJ-SCHIP1 with IQ-like motif AAA PF00004.29 OAP54807.1 - 0.14 12.6 0.0 1.4 9.3 0.0 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF1409 PF07197.12 OAP54807.1 - 0.81 9.6 5.0 48 4.0 0.0 5.2 8 0 0 8 8 8 0 Protein of unknown function (DUF1409) DUF892 PF05974.12 OAP54807.1 - 7.6 6.5 7.0 1.9e+02 2.0 0.0 5.1 6 0 0 6 6 6 0 Domain of unknown function (DUF892) RrnaAD PF00398.20 OAP54809.1 - 5.1e-63 212.6 0.0 7.9e-63 212.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 OAP54809.1 - 5.1e-06 27.1 0.0 1e-05 26.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAP54809.1 - 7.3e-05 23.3 0.0 0.00015 22.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 OAP54809.1 - 0.0016 18.2 0.0 0.0024 17.7 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 OAP54809.1 - 0.002 18.0 0.0 0.0037 17.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAP54809.1 - 0.0027 18.4 0.0 0.0063 17.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 OAP54809.1 - 0.0061 15.9 0.0 0.0093 15.3 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.18 OAP54809.1 - 0.031 13.6 0.0 0.052 12.9 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain MTS PF05175.14 OAP54809.1 - 0.033 13.8 0.0 0.053 13.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain AAA_lid_4 PF17864.1 OAP54809.1 - 0.11 12.3 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 RuvB AAA lid domain PrmA PF06325.13 OAP54809.1 - 0.11 11.8 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) PRP1_N PF06424.12 OAP54810.1 - 6.5e-49 166.1 5.8 1.5e-48 164.9 5.8 1.7 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.6 OAP54810.1 - 2e-28 96.6 41.6 5.9e-06 26.7 0.4 14.3 6 5 10 16 16 15 10 Tetratricopeptide repeat TPR_19 PF14559.6 OAP54810.1 - 1e-24 86.8 16.9 1.9e-08 34.6 0.4 9.3 5 3 3 8 8 8 5 Tetratricopeptide repeat TPR_17 PF13431.6 OAP54810.1 - 2.5e-12 46.3 3.7 6.3 7.4 0.0 10.9 9 2 2 11 11 11 1 Tetratricopeptide repeat TPR_2 PF07719.17 OAP54810.1 - 2.8e-12 45.8 12.5 0.13 12.4 0.0 10.1 12 0 0 12 12 10 3 Tetratricopeptide repeat TPR_8 PF13181.6 OAP54810.1 - 3.3e-10 39.4 0.4 0.073 13.3 0.0 7.1 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_16 PF13432.6 OAP54810.1 - 2.2e-09 37.8 20.2 0.2 12.3 3.4 8.4 7 2 2 9 9 9 3 Tetratricopeptide repeat TPR_11 PF13414.6 OAP54810.1 - 2.3e-07 30.4 1.0 1.5 8.6 0.0 6.4 6 0 0 6 6 6 2 TPR repeat TPR_9 PF13371.6 OAP54810.1 - 3.9e-06 26.9 11.5 0.88 9.8 0.0 6.7 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_1 PF00515.28 OAP54810.1 - 1e-05 25.1 0.0 0.61 10.0 0.0 4.2 3 0 0 3 3 3 2 Tetratricopeptide repeat NARP1 PF12569.8 OAP54810.1 - 6.5e-05 22.0 9.3 1.3 7.9 0.0 5.9 5 1 2 7 7 7 2 NMDA receptor-regulated protein 1 TPR_21 PF09976.9 OAP54810.1 - 7.6e-05 22.5 6.7 0.038 13.7 0.6 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat-like domain ANAPC3 PF12895.7 OAP54810.1 - 0.0004 20.5 0.3 18 5.7 0.0 5.5 6 1 2 8 8 7 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 OAP54810.1 - 0.002 17.4 7.3 0.002 17.4 7.3 6.3 3 2 1 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 OAP54810.1 - 0.0058 17.2 9.3 54 4.7 0.1 8.6 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_7 PF13176.6 OAP54810.1 - 0.023 14.7 0.5 4.2 7.6 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat ER-remodelling PF14755.6 OAP54810.1 - 0.092 13.0 0.3 0.4 11.0 0.3 2.1 1 0 0 1 1 1 0 Intracellular membrane remodeller BTAD PF03704.17 OAP54810.1 - 3 8.3 12.0 1.5 9.3 0.3 4.1 3 1 1 4 4 4 0 Bacterial transcriptional activator domain GFA PF04828.14 OAP54811.1 - 3.4e-10 40.1 0.6 3.4e-10 40.1 0.6 1.8 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme zf-C2H2_6 PF13912.6 OAP54812.1 - 0.0003 20.7 0.6 0.0035 17.3 0.1 7.1 7 0 0 7 7 7 2 C2H2-type zinc finger zf-C2H2_4 PF13894.6 OAP54812.1 - 0.041 14.7 0.1 0.041 14.7 0.1 8.2 8 0 0 8 8 8 0 C2H2-type zinc finger zf-C2H2 PF00096.26 OAP54812.1 - 0.051 14.0 0.1 0.051 14.0 0.1 8.8 9 1 0 9 9 9 0 Zinc finger, C2H2 type NDUF_B12 PF08122.12 OAP54812.1 - 0.21 11.7 0.6 0.47 10.5 0.6 1.6 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B12 subunit family Yippee-Mis18 PF03226.14 OAP54813.1 - 5.5e-24 84.4 0.7 8.6e-24 83.8 0.7 1.2 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.8 OAP54813.1 - 0.049 13.9 2.1 2.1 8.6 0.0 2.2 2 0 0 2 2 2 0 C-terminal domain of RIG-I Ribosomal_S27e PF01667.17 OAP54813.1 - 0.34 10.7 2.7 14 5.4 0.4 2.3 2 0 0 2 2 2 0 Ribosomal protein S27 Fungal_trans_2 PF11951.8 OAP54814.1 - 1.5e-12 47.1 0.0 2.1e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short_C2 PF13561.6 OAP54815.1 - 6.2e-45 153.6 0.1 7.4e-45 153.3 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP54815.1 - 2.5e-33 115.2 0.1 3.1e-33 114.9 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAP54815.1 - 3.3e-10 40.2 0.5 4.2e-10 39.8 0.5 1.1 1 0 0 1 1 1 1 KR domain Dak1_2 PF13684.6 OAP54815.1 - 0.042 12.9 0.1 0.12 11.4 0.0 1.7 2 0 0 2 2 2 0 Dihydroxyacetone kinase family GDP_Man_Dehyd PF16363.5 OAP54815.1 - 0.075 12.4 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 OAP54815.1 - 0.14 11.6 0.1 0.19 11.2 0.1 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family BON PF04972.17 OAP54815.1 - 0.14 12.5 0.3 2.6 8.4 0.0 2.2 2 0 0 2 2 2 0 BON domain SLATT_fungal PF18142.1 OAP54816.1 - 1.3e-30 105.9 0.0 1.7e-30 105.4 0.0 1.2 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain PPR_2 PF13041.6 OAP54817.1 - 2.6e-07 30.7 0.0 1.8 8.8 0.0 5.9 6 0 0 6 6 6 3 PPR repeat family PPR PF01535.20 OAP54817.1 - 1.7e-05 24.7 0.0 11 6.6 0.0 5.4 5 0 0 5 5 5 2 PPR repeat TPR_19 PF14559.6 OAP54817.1 - 0.067 13.7 1.9 27 5.4 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 OAP54817.1 - 0.82 10.7 9.7 27 5.9 0.1 5.5 4 1 1 5 5 5 0 Tetratricopeptide repeat WD40 PF00400.32 OAP54819.1 - 3.8e-30 103.5 26.6 0.00043 21.0 1.7 10.9 11 0 0 11 11 11 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAP54819.1 - 1.6e-15 57.2 1.5 0.018 15.3 0.1 6.6 3 3 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 OAP54819.1 - 0.00071 19.4 1.8 8.1 6.5 0.0 4.6 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat DUF1513 PF07433.11 OAP54819.1 - 0.011 14.9 0.6 0.8 8.7 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1513) eIF2A PF08662.11 OAP54819.1 - 0.012 15.5 0.9 2.8 7.8 0.1 3.7 3 3 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 OAP54819.1 - 0.16 10.9 3.8 5.3 5.9 0.1 4.1 3 2 3 6 6 6 0 WD40 region of Ge1, enhancer of mRNA-decapping protein SAGA-Tad1 PF12767.7 OAP54820.1 - 2.2e-54 184.7 0.0 3e-54 184.3 0.0 1.2 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit Arginase PF00491.21 OAP54821.1 - 5.8e-86 288.5 0.0 7.6e-86 288.1 0.0 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 OAP54821.1 - 0.17 12.1 0.0 0.36 11.0 0.0 1.6 1 1 1 2 2 2 0 UPF0489 domain Formyl_trans_N PF00551.19 OAP54822.1 - 1.1e-37 129.5 0.2 1.4e-37 129.2 0.2 1.1 1 0 0 1 1 1 1 Formyl transferase ACT PF01842.25 OAP54822.1 - 1.2e-10 41.0 0.0 3.5e-10 39.5 0.0 1.8 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.6 OAP54822.1 - 2.3e-05 24.3 0.0 5.3e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 ACT domain Ank_2 PF12796.7 OAP54823.1 - 1.9e-30 105.3 0.8 4e-09 36.9 0.0 8.1 8 0 0 8 8 8 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAP54823.1 - 2.3e-22 79.1 0.4 4e-05 24.1 0.0 8.3 6 2 2 8 8 8 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAP54823.1 - 6.9e-22 75.2 4.2 0.00063 20.0 0.0 10.3 10 0 0 10 10 10 4 Ankyrin repeat Ank PF00023.30 OAP54823.1 - 1.3e-20 72.9 5.5 0.00028 21.2 0.0 8.5 8 0 0 8 8 8 3 Ankyrin repeat Ank_5 PF13857.6 OAP54823.1 - 1.7e-18 66.4 2.0 0.018 15.4 0.0 9.2 7 2 1 9 9 9 4 Ankyrin repeats (many copies) FbpA PF05833.11 OAP54824.1 - 6.6e-37 127.3 0.5 6.6e-37 127.3 0.5 2.0 2 1 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) NFACT-R_1 PF05670.13 OAP54824.1 - 7.2e-32 110.3 0.0 2.6e-31 108.5 0.0 2.0 2 0 0 2 2 2 1 NFACT protein RNA binding domain NFACT-C PF11923.8 OAP54824.1 - 7.9e-31 106.1 0.0 7.9e-31 106.1 0.0 3.5 5 0 0 5 5 5 1 NFACT protein C-terminal domain Pneumo_att_G PF05539.11 OAP54824.1 - 5.7 6.4 9.6 9.8 5.7 9.6 1.3 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Clat_adaptor_s PF01217.20 OAP54825.1 - 1.3e-12 47.8 0.1 5e-12 45.9 0.3 1.6 2 0 0 2 2 2 1 Clathrin adaptor complex small chain Peptidase_S80 PF07230.11 OAP54825.1 - 0.0012 17.2 0.0 0.0016 16.8 0.0 1.2 1 0 0 1 1 1 1 Bacteriophage T4-like capsid assembly protein (Gp20) DUF4804 PF16062.5 OAP54825.1 - 0.011 14.6 0.0 0.013 14.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4804) FtsJ PF01728.19 OAP54826.1 - 2.9e-61 206.7 0.0 4.1e-61 206.2 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase UCH PF00443.29 OAP54827.1 - 1.1e-48 165.9 0.0 1.7e-48 165.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OAP54827.1 - 1.4e-16 61.0 0.1 9.9e-13 48.4 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.20 OAP54827.1 - 0.003 18.1 0.0 0.0075 16.8 0.0 1.8 1 0 0 1 1 1 1 Rhodanese-like domain VHS PF00790.19 OAP54828.1 - 3.6e-42 143.6 1.9 7.5e-41 139.3 0.2 2.5 2 0 0 2 2 2 1 VHS domain FYVE PF01363.21 OAP54828.1 - 3.3e-16 59.2 1.8 5.9e-16 58.4 1.8 1.4 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.20 OAP54828.1 - 4.9e-08 32.4 12.1 0.00041 20.1 2.6 3.3 3 0 0 3 3 3 2 Ubiquitin interaction motif GAT PF03127.14 OAP54828.1 - 3.5e-05 24.0 1.1 8.6e-05 22.8 0.0 2.3 3 0 0 3 3 3 1 GAT domain FYVE_2 PF02318.16 OAP54828.1 - 0.049 13.9 0.5 0.11 12.7 0.5 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger C1_1 PF00130.22 OAP54828.1 - 0.057 13.3 2.6 0.12 12.2 2.6 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Ribosomal_S30AE PF02482.19 OAP54828.1 - 0.072 13.9 0.1 2.2 9.1 0.3 2.5 2 0 0 2 2 2 0 Sigma 54 modulation protein / S30EA ribosomal protein Npa1 PF11707.8 OAP54828.1 - 0.1 11.9 0.1 0.17 11.2 0.1 1.3 1 0 0 1 1 1 0 Ribosome 60S biogenesis N-terminal DZR PF12773.7 OAP54828.1 - 0.38 10.8 3.2 0.82 9.7 3.2 1.5 1 0 0 1 1 1 0 Double zinc ribbon OAD_gamma PF04277.13 OAP54828.1 - 1 10.0 2.8 2 9.0 1.2 2.4 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Sua5_yciO_yrdC PF01300.18 OAP54829.1 - 1.9e-52 177.4 0.0 3.2e-52 176.6 0.0 1.3 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 OAP54829.1 - 1.5e-15 58.0 0.0 2.3e-14 54.1 0.0 2.6 1 1 0 1 1 1 1 Putative GTP-binding controlling metal-binding HLH PF00010.26 OAP54829.1 - 0.22 11.5 0.0 0.49 10.4 0.0 1.5 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain MFS_1 PF07690.16 OAP54830.1 - 1.5e-27 96.5 33.6 9.2e-27 93.9 28.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily YjcB PF15940.5 OAP54830.1 - 0.27 11.4 4.2 0.66 10.2 0.1 3.1 3 0 0 3 3 3 0 Family of unknown function Amidase PF01425.21 OAP54831.1 - 1.7e-90 304.2 0.0 8.2e-90 301.9 0.0 1.8 1 1 0 1 1 1 1 Amidase DUF5132 PF17195.4 OAP54831.1 - 0.12 12.5 0.2 1.1 9.4 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF5132) Putative_PNPOx PF01243.20 OAP54833.1 - 2.4e-08 34.1 0.0 2.4e-05 24.4 0.0 2.6 2 0 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase FAD_binding_6 PF00970.24 OAP54833.1 - 0.0064 16.8 0.0 0.46 10.9 0.0 3.0 2 1 0 2 2 2 1 Oxidoreductase FAD-binding domain HSP70 PF00012.20 OAP54835.1 - 5.8e-264 876.8 11.9 6.6e-264 876.7 11.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 OAP54835.1 - 1.4e-18 66.8 2.5 2.6e-17 62.7 1.0 2.1 2 0 0 2 2 2 2 MreB/Mbl protein DDR PF08841.10 OAP54835.1 - 0.0027 16.8 0.6 0.032 13.2 0.3 2.1 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain RTX_C PF08339.10 OAP54835.1 - 0.024 14.7 0.2 6.7 6.7 0.0 2.6 2 0 0 2 2 2 0 RTX C-terminal domain Hydantoinase_A PF01968.18 OAP54835.1 - 0.48 9.6 5.1 0.41 9.8 0.1 2.8 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase FtsA PF14450.6 OAP54835.1 - 0.58 10.6 7.5 8.5 6.9 0.3 3.6 3 2 0 3 3 3 0 Cell division protein FtsA GST_N_2 PF13409.6 OAP54836.1 - 3.8e-20 72.0 0.0 6.2e-20 71.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 OAP54836.1 - 1.4e-18 67.1 0.0 2.4e-18 66.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 OAP54836.1 - 3.3e-10 40.1 0.1 7.6e-10 39.0 0.1 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAP54836.1 - 3.5e-09 36.5 0.1 8e-09 35.4 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 OAP54836.1 - 0.00034 21.1 0.0 0.00058 20.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OAP54836.1 - 0.0011 19.1 0.0 0.002 18.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OAP54836.1 - 0.0048 17.1 0.0 0.0078 16.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain F-actin_cap_A PF01267.17 OAP54837.1 - 1.5e-83 280.3 0.0 1.7e-83 280.1 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit GTP_EFTU PF00009.27 OAP54839.1 - 6.9e-49 166.0 0.0 1.2e-48 165.2 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.10 OAP54839.1 - 2.1e-23 82.4 0.6 4.4e-23 81.4 0.6 1.5 1 0 0 1 1 1 1 HBS1 N-terminus GTP_EFTU_D3 PF03143.17 OAP54839.1 - 5.7e-11 42.7 0.1 2e-09 37.7 0.0 2.8 3 0 0 3 3 3 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 OAP54839.1 - 9.4e-09 35.4 0.7 3e-06 27.3 0.0 3.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 OAP54839.1 - 1.1e-07 32.1 0.0 2.5e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 SRPRB PF09439.10 OAP54839.1 - 0.013 14.9 0.9 1.1 8.6 0.1 3.1 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit Roc PF08477.13 OAP54839.1 - 0.015 15.5 0.4 2.3 8.4 0.0 3.0 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 OAP54839.1 - 0.017 14.5 0.0 0.035 13.5 0.0 1.5 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 OAP54839.1 - 0.027 14.0 0.2 0.74 9.3 0.1 2.9 2 1 0 2 2 2 0 Ferrous iron transport protein B G-alpha PF00503.20 OAP54839.1 - 0.13 11.4 0.4 4 6.5 0.0 2.5 3 0 0 3 3 3 0 G-protein alpha subunit ToxB_N PF18224.1 OAP54840.1 - 0.05 13.5 0.1 0.15 12.0 0.1 1.8 1 0 0 1 1 1 0 ToxB N-terminal domain Fructosamin_kin PF03881.14 OAP54843.1 - 8.5e-26 90.8 0.1 2.8e-18 66.1 0.1 2.1 1 1 1 2 2 2 2 Fructosamine kinase APH PF01636.23 OAP54843.1 - 0.00022 21.2 0.0 0.46 10.4 0.0 2.2 2 0 0 2 2 2 2 Phosphotransferase enzyme family Zn_clus PF00172.18 OAP54844.1 - 1.3e-06 28.4 7.4 2.3e-06 27.6 7.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAP54844.1 - 4.6e-05 22.6 0.9 0.00052 19.1 0.2 2.4 2 0 0 2 2 2 1 Fungal specific transcription factor domain FAD_binding_3 PF01494.19 OAP54845.1 - 1e-57 196.0 0.0 1.3e-57 195.7 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Nitroreductase PF00881.24 OAP54846.1 - 3e-15 56.7 0.1 3.5e-15 56.4 0.1 1.1 1 0 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 OAP54846.1 - 0.11 12.1 0.0 0.22 11.1 0.0 1.5 2 0 0 2 2 2 0 Putative TM nitroreductase GST_N PF02798.20 OAP54847.1 - 2.8e-05 24.3 0.0 6.1e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAP54847.1 - 0.0002 21.3 0.0 0.00045 20.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 OAP54847.1 - 0.0057 17.0 0.0 0.013 15.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Ead_Ea22 PF13935.6 OAP54847.1 - 0.01 16.5 0.0 0.56 10.9 0.0 2.2 2 0 0 2 2 2 0 Ead/Ea22-like protein p450 PF00067.22 OAP54848.1 - 2.2e-59 201.4 0.0 2.9e-59 201.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 OAP54849.1 - 1.7e-14 53.5 8.0 2e-14 53.3 8.0 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAP54849.1 - 0.00011 21.3 0.4 0.00012 21.1 0.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MOZART1 PF12554.8 OAP54849.1 - 0.091 12.6 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Mitotic-spindle organizing gamma-tubulin ring associated MFS_1 PF07690.16 OAP54850.1 - 2.6e-15 56.2 0.4 3e-15 56.0 0.4 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 OAP54850.1 - 0.13 10.6 0.0 0.15 10.5 0.0 1.0 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) CBF PF03914.17 OAP54852.1 - 1.4e-34 119.5 0.5 3e-34 118.5 0.1 1.7 1 1 1 2 2 2 1 CBF/Mak21 family Mt_ATP-synt_B PF05405.14 OAP54853.1 - 3.5e-53 179.6 6.8 4.4e-53 179.2 6.8 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF1539 PF07560.11 OAP54853.1 - 0.14 12.3 2.0 0.14 12.3 0.8 1.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1539) Fib_alpha PF08702.10 OAP54853.1 - 0.34 11.1 7.5 3.4 7.8 7.3 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family TPR_19 PF14559.6 OAP54854.1 - 1.3e-13 51.2 15.0 0.00067 20.1 0.0 6.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 OAP54854.1 - 5e-09 36.7 26.2 0.00057 20.5 0.1 8.0 6 2 2 8 8 8 3 Tetratricopeptide repeat TPR_2 PF07719.17 OAP54854.1 - 3.7e-08 32.9 35.0 0.44 10.8 0.1 11.2 13 0 0 13 13 12 3 Tetratricopeptide repeat TPR_14 PF13428.6 OAP54854.1 - 3.9e-06 27.2 32.8 1.9 9.5 0.0 9.7 9 3 2 11 11 9 4 Tetratricopeptide repeat TPR_8 PF13181.6 OAP54854.1 - 8.5e-06 25.6 19.7 0.089 13.1 0.0 9.1 10 0 0 10 10 9 1 Tetratricopeptide repeat TPR_7 PF13176.6 OAP54854.1 - 0.00034 20.4 9.3 11 6.3 0.0 8.0 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_9 PF13371.6 OAP54854.1 - 0.0019 18.3 11.6 0.0024 18.0 0.5 5.1 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 OAP54854.1 - 0.0024 18.1 5.6 45 4.7 0.0 7.6 9 0 0 9 9 8 0 Tetratricopeptide repeat ANAPC3 PF12895.7 OAP54854.1 - 0.0038 17.4 14.2 0.37 11.0 0.7 5.3 4 1 1 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.6 OAP54854.1 - 0.011 15.8 0.3 2.8 8.1 0.0 4.0 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_1 PF00515.28 OAP54854.1 - 0.014 15.2 27.9 1.6 8.7 0.0 9.1 11 0 0 11 11 10 0 Tetratricopeptide repeat TPR_11 PF13414.6 OAP54854.1 - 0.019 14.6 5.5 0.59 9.9 0.0 4.6 4 1 1 5 5 5 0 TPR repeat TPR_12 PF13424.6 OAP54854.1 - 0.038 14.3 25.3 0.24 11.7 0.8 6.8 6 1 1 7 7 6 0 Tetratricopeptide repeat ANAPC5 PF12862.7 OAP54854.1 - 0.043 13.9 0.1 0.25 11.4 0.0 2.4 2 0 0 2 2 1 0 Anaphase-promoting complex subunit 5 TPR_20 PF14561.6 OAP54854.1 - 0.044 14.1 9.4 2.8 8.3 0.4 4.8 2 1 2 4 4 4 0 Tetratricopeptide repeat NARP1 PF12569.8 OAP54854.1 - 0.063 12.2 9.7 0.83 8.5 0.7 3.3 3 0 0 3 3 3 0 NMDA receptor-regulated protein 1 GST_C_3 PF14497.6 OAP54854.1 - 0.14 12.3 0.0 0.51 10.6 0.0 2.0 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain ADH_N PF08240.12 OAP54855.1 - 3.1e-25 88.2 2.0 6.9e-25 87.1 2.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAP54855.1 - 5.7e-20 71.6 0.3 1.1e-19 70.6 0.3 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Sacchrp_dh_NADP PF03435.18 OAP54855.1 - 3e-05 24.3 0.1 6.1e-05 23.3 0.1 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Glu_dehyd_C PF16912.5 OAP54855.1 - 0.00029 20.4 0.1 0.0014 18.1 0.1 1.9 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 OAP54855.1 - 0.00036 19.9 1.0 0.00061 19.1 1.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.6 OAP54855.1 - 0.0019 19.2 0.0 0.0042 18.1 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.14 OAP54855.1 - 0.028 14.0 0.1 0.047 13.3 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.18 OAP54855.1 - 0.081 13.2 0.1 0.14 12.4 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain Pep_deformylase PF01327.21 OAP54855.1 - 0.1 12.2 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Polypeptide deformylase IGFBP PF00219.18 OAP54855.1 - 0.12 13.0 0.3 0.12 13.0 0.3 2.0 2 0 0 2 2 2 0 Insulin-like growth factor binding protein GDPD PF03009.17 OAP54856.1 - 3.5e-33 115.4 0.0 5.1e-33 114.9 0.0 1.2 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.6 OAP54856.1 - 0.0037 17.7 0.4 0.011 16.1 0.4 1.9 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Amidase PF01425.21 OAP54857.1 - 9.1e-75 252.3 0.0 1.2e-74 251.9 0.0 1.1 1 0 0 1 1 1 1 Amidase Polysacc_deac_1 PF01522.21 OAP54858.1 - 1.3e-13 50.9 0.0 2.2e-13 50.2 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase Tubulin PF00091.25 OAP54859.1 - 2.1e-69 233.7 0.0 3.1e-69 233.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 OAP54859.1 - 2.7e-45 153.6 0.4 7.3e-45 152.2 0.1 1.7 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 OAP54859.1 - 5e-07 30.0 0.0 1.2e-06 28.8 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 OAP54859.1 - 0.053 13.2 0.0 0.14 11.8 0.0 1.7 1 0 0 1 1 1 0 Tubulin domain Tubulin_2 PF13809.6 OAP54859.1 - 0.067 12.4 0.0 0.097 11.8 0.0 1.2 1 0 0 1 1 1 0 Tubulin like zf-AN1 PF01428.16 OAP54860.1 - 1.6e-10 41.0 6.4 2.2e-10 40.5 6.4 1.2 1 0 0 1 1 1 1 AN1-like Zinc finger Rad60-SLD PF11976.8 OAP54860.1 - 5.1e-09 35.8 0.0 7.2e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 OAP54860.1 - 1.3e-07 31.3 0.1 2.1e-07 30.6 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin family Transp_Tc5_C PF04236.15 OAP54860.1 - 0.0037 17.6 0.5 0.0058 17.0 0.5 1.3 1 0 0 1 1 1 1 Tc5 transposase C-terminal domain NAM-associated PF14303.6 OAP54860.1 - 0.17 12.6 2.3 0.31 11.7 2.3 1.4 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Pmp3 PF01679.17 OAP54862.1 - 5.3e-25 87.4 8.6 5.9e-25 87.2 8.6 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator TM_helix PF05552.12 OAP54862.1 - 5 7.2 8.2 1.5 8.9 2.4 2.0 2 0 0 2 2 2 0 Conserved TM helix Herpes_gE PF02480.16 OAP54863.1 - 0.0079 15.0 0.0 0.013 14.2 0.0 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Pcc1 PF09341.10 OAP54864.1 - 7.3e-29 99.7 0.1 8.6e-29 99.5 0.1 1.1 1 0 0 1 1 1 1 Transcription factor Pcc1 DSPn PF14671.6 OAP54865.1 - 3.3e-42 144.3 0.0 6e-40 137.0 0.0 2.4 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 OAP54865.1 - 3.9e-17 62.3 0.2 8.7e-17 61.2 0.0 1.6 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 OAP54865.1 - 1.8e-05 24.4 0.0 3.7e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 OAP54865.1 - 0.019 15.1 0.0 0.053 13.6 0.0 1.8 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 OAP54865.1 - 0.14 12.1 0.1 0.26 11.2 0.1 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family SDP_N PF12278.8 OAP54865.1 - 0.19 11.9 0.4 0.54 10.4 0.4 1.8 1 0 0 1 1 1 0 Sex determination protein N terminal Ribosomal_L22e PF01776.17 OAP54866.1 - 5.2e-48 162.0 0.2 6.2e-48 161.7 0.2 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family Methyltransf_34 PF11312.8 OAP54867.1 - 2.7e-102 342.1 0.0 3.2e-102 341.9 0.0 1.0 1 0 0 1 1 1 1 Putative SAM-dependent methyltransferase HCNGP PF07818.13 OAP54869.1 - 2.5e-29 101.8 0.0 3.9e-29 101.1 0.0 1.3 1 0 0 1 1 1 1 HCNGP-like protein Sec16_N PF12935.7 OAP54869.1 - 0.051 13.7 2.2 1 9.5 0.1 2.4 2 0 0 2 2 2 0 Vesicle coat trafficking protein Sec16 N-terminus DUF2706 PF10913.8 OAP54869.1 - 0.22 11.4 0.4 0.39 10.6 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2706) RhoGAP PF00620.27 OAP54870.1 - 2.4e-40 137.9 0.2 5.3e-40 136.7 0.2 1.6 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.29 OAP54870.1 - 2.8e-15 56.7 0.0 5.8e-15 55.7 0.0 1.6 1 0 0 1 1 1 1 PH domain PX PF00787.24 OAP54870.1 - 0.0014 18.6 0.1 0.0045 17.0 0.0 1.9 2 0 0 2 2 2 1 PX domain APG6_N PF17675.1 OAP54870.1 - 0.26 11.8 0.1 0.26 11.8 0.1 2.6 2 0 0 2 2 2 0 Apg6 coiled-coil region MFS_1 PF07690.16 OAP54871.1 - 5.4e-18 65.0 35.3 5.4e-18 65.0 35.3 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Iso_dh PF00180.20 OAP54872.1 - 3e-83 279.9 0.1 3.7e-83 279.6 0.1 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase NMO PF03060.15 OAP54873.1 - 4.2e-53 180.9 1.6 5.5e-53 180.5 1.6 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 OAP54873.1 - 1.6e-08 33.9 0.0 2.6e-07 30.0 0.0 2.3 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 OAP54873.1 - 0.0079 15.3 3.2 0.014 14.5 3.2 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase PEP_hydrolase PF09370.10 OAP54873.1 - 0.043 13.0 0.0 0.072 12.3 0.0 1.3 1 0 0 1 1 1 0 Phosphoenolpyruvate hydrolase-like DNA_methylase PF00145.17 OAP54876.1 - 4.5e-07 29.5 0.0 4.9e-06 26.1 0.0 2.1 1 1 0 2 2 2 1 C-5 cytosine-specific DNA methylase ABC_membrane PF00664.23 OAP54877.1 - 1.5e-60 205.2 38.9 2.4e-37 129.1 17.6 3.2 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 OAP54877.1 - 1e-48 165.3 0.0 1.2e-27 97.1 0.0 3.0 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 OAP54877.1 - 3.8e-07 29.8 0.6 0.29 10.5 0.1 3.9 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 OAP54877.1 - 2.4e-06 27.6 0.1 0.0097 16.0 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_21 PF13304.6 OAP54877.1 - 1.1e-05 25.4 0.1 0.17 11.6 0.0 3.3 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 OAP54877.1 - 3.2e-05 24.4 0.2 0.45 10.9 0.0 3.7 2 1 1 3 3 3 2 AAA ATPase domain AAA_29 PF13555.6 OAP54877.1 - 4.2e-05 23.2 0.7 0.28 11.0 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 OAP54877.1 - 0.00014 21.8 0.9 0.58 10.0 0.1 3.1 3 0 0 3 3 3 2 RsgA GTPase Zeta_toxin PF06414.12 OAP54877.1 - 0.00029 20.2 0.0 0.026 13.8 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_22 PF13401.6 OAP54877.1 - 0.0014 19.0 1.0 2.7 8.2 0.1 3.2 2 1 0 2 2 2 2 AAA domain AAA_15 PF13175.6 OAP54877.1 - 0.0016 18.3 0.1 1.9 8.1 0.0 2.8 2 1 0 2 2 2 2 AAA ATPase domain IstB_IS21 PF01695.17 OAP54877.1 - 0.014 15.2 0.1 0.8 9.4 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_30 PF13604.6 OAP54877.1 - 0.015 15.0 2.9 2.4 7.8 0.1 3.0 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.6 OAP54877.1 - 0.026 15.1 0.0 3.9 8.0 0.0 2.9 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 OAP54877.1 - 0.034 14.2 6.1 0.58 10.2 0.1 3.2 3 0 0 3 3 3 0 Dynamin family NACHT PF05729.12 OAP54877.1 - 0.042 13.8 0.4 0.36 10.7 0.0 2.4 2 0 0 2 2 2 0 NACHT domain Ploopntkinase3 PF18751.1 OAP54877.1 - 0.046 13.6 0.0 14 5.5 0.0 2.7 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_7 PF12775.7 OAP54877.1 - 0.053 13.0 0.1 4.2 6.8 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region Roc PF08477.13 OAP54877.1 - 0.053 13.7 0.1 13 6.0 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase MeaB PF03308.16 OAP54877.1 - 0.074 12.0 0.4 6.1 5.7 0.0 2.4 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 OAP54877.1 - 0.2 11.2 0.8 1.5 8.3 0.2 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.17 OAP54877.1 - 0.23 11.5 6.3 0.24 11.5 0.1 2.6 2 1 0 2 2 2 0 Helicase HerA, central domain AAA_23 PF13476.6 OAP54877.1 - 0.3 11.5 0.0 0.3 11.5 0.0 3.9 3 1 1 4 4 3 0 AAA domain AAA_28 PF13521.6 OAP54877.1 - 0.4 10.9 4.4 0.49 10.6 0.2 3.0 3 0 0 3 3 2 0 AAA domain Sec62 PF03839.16 OAP54877.1 - 0.54 9.7 2.6 18 4.7 0.1 2.8 2 0 0 2 2 2 0 Translocation protein Sec62 AP3D1 PF06375.11 OAP54877.1 - 0.55 10.5 11.7 1 9.6 2.6 2.6 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 ATP_bind_1 PF03029.17 OAP54877.1 - 0.71 9.6 3.4 13 5.5 0.2 3.1 4 0 0 4 4 3 0 Conserved hypothetical ATP binding protein adh_short PF00106.25 OAP54878.1 - 4.2e-41 140.6 0.0 5.5e-41 140.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP54878.1 - 6.8e-28 97.8 0.0 9e-28 97.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP54878.1 - 0.00015 21.7 0.0 0.0002 21.3 0.0 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 OAP54878.1 - 0.0082 16.1 0.0 0.022 14.6 0.0 1.9 1 1 1 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 OAP54878.1 - 0.087 12.3 0.0 0.35 10.3 0.0 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Vitellogenin_N PF01347.22 OAP54878.1 - 0.13 10.7 0.0 0.17 10.3 0.0 1.1 1 0 0 1 1 1 0 Lipoprotein amino terminal region RPN7 PF10602.9 OAP54878.1 - 0.24 11.1 0.0 0.37 10.5 0.0 1.2 1 0 0 1 1 1 0 26S proteasome subunit RPN7 Fer2_3 PF13085.6 OAP54879.1 - 1.1e-31 109.0 0.0 1.8e-31 108.4 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 OAP54879.1 - 1.8e-08 34.8 6.0 1.8e-08 34.8 6.0 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 OAP54879.1 - 2.1e-07 31.3 8.1 2.1e-07 31.3 8.1 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 OAP54879.1 - 4.9e-07 29.8 2.6 4.9e-07 29.8 2.6 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 OAP54879.1 - 0.0014 19.1 4.0 0.0014 19.1 4.0 2.4 2 2 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 OAP54879.1 - 0.011 15.6 0.4 0.011 15.6 0.4 2.2 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain Fer4_18 PF13746.6 OAP54879.1 - 0.076 13.2 2.5 0.84 9.9 0.2 2.7 3 0 0 3 3 3 0 4Fe-4S dicluster domain SF3a60_bindingd PF12108.8 OAP54879.1 - 0.19 11.6 2.2 0.25 11.3 0.4 2.0 2 0 0 2 2 2 0 Splicing factor SF3a60 binding domain Fer4_9 PF13187.6 OAP54879.1 - 2.2 8.5 12.0 28 5.0 10.3 2.9 2 1 2 4 4 4 0 4Fe-4S dicluster domain AIG2_2 PF13772.6 OAP54880.1 - 9.2e-06 26.0 0.0 3e-05 24.3 0.0 2.0 1 1 0 1 1 1 1 AIG2-like family GATase_6 PF13522.6 OAP54882.1 - 1.8e-08 34.7 0.2 3.3e-08 33.8 0.2 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 OAP54882.1 - 3.5e-08 32.7 0.2 4.3e-07 29.1 0.2 2.2 1 1 0 1 1 1 1 Glutamine amidotransferases class-II ABC_tran PF00005.27 OAP54883.1 - 5.1e-31 108.0 0.1 1.2e-17 64.7 0.0 3.2 3 0 0 3 3 3 2 ABC transporter ABC_membrane PF00664.23 OAP54883.1 - 6.8e-29 101.4 18.9 3.1e-21 76.2 11.1 2.7 2 1 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.6 OAP54883.1 - 7.5e-06 26.0 2.0 0.0064 16.3 0.0 2.9 2 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 OAP54883.1 - 0.00019 21.9 0.0 0.4 11.0 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 OAP54883.1 - 0.0035 17.6 0.0 0.044 14.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain DnaB_C PF03796.15 OAP54883.1 - 0.0052 16.1 0.0 0.01 15.2 0.0 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain DUF1286 PF06939.11 OAP54883.1 - 0.0056 16.9 0.1 0.0056 16.9 0.1 3.6 4 0 0 4 4 4 1 Protein of unknown function (DUF1286) AAA_24 PF13479.6 OAP54883.1 - 0.015 15.1 0.0 0.15 11.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 OAP54883.1 - 0.032 14.0 0.2 1.4 8.8 0.1 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain NACHT PF05729.12 OAP54883.1 - 0.058 13.3 0.0 1.9 8.4 0.0 2.7 2 0 0 2 2 2 0 NACHT domain T2SSE PF00437.20 OAP54883.1 - 0.063 12.3 1.9 0.45 9.5 0.0 2.6 3 0 0 3 3 3 0 Type II/IV secretion system protein AAA PF00004.29 OAP54883.1 - 0.065 13.7 0.0 8.8 6.8 0.0 3.0 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 OAP54883.1 - 0.1 12.1 0.0 2.3 7.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 OAP54883.1 - 0.14 12.7 0.0 0.36 11.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 OAP54883.1 - 0.17 12.2 0.0 0.43 10.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain Glyco_hydro_47 PF01532.20 OAP54884.1 - 1.2e-168 561.8 1.6 1.5e-168 561.5 1.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 WBS_methylT PF12589.8 OAP54885.1 - 5e-13 49.6 3.5 8.1e-13 48.9 3.5 1.3 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.12 OAP54885.1 - 3.7e-11 43.5 0.0 7.2e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAP54885.1 - 8.7e-11 42.4 0.0 1.9e-10 41.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAP54885.1 - 1.4e-05 25.7 0.0 3.5e-05 24.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAP54885.1 - 0.00014 21.8 0.0 0.00019 21.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 OAP54885.1 - 0.0004 20.2 0.0 0.00063 19.6 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 OAP54885.1 - 0.0022 17.8 0.0 0.0035 17.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAP54885.1 - 0.011 15.0 0.2 0.043 13.1 0.0 2.0 2 1 0 3 3 3 0 ubiE/COQ5 methyltransferase family AdoMet_MTase PF07757.13 OAP54885.1 - 0.011 16.0 0.0 0.027 14.8 0.0 1.7 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase CMAS PF02353.20 OAP54885.1 - 0.049 12.9 0.0 0.079 12.2 0.0 1.4 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase AA_permease_2 PF13520.6 OAP54886.1 - 1.7e-59 201.8 51.0 2.1e-59 201.5 51.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAP54886.1 - 8.1e-25 87.3 43.3 8.1e-25 87.3 43.3 2.0 1 1 1 2 2 2 2 Amino acid permease Phage_CII PF05269.11 OAP54886.1 - 0.048 13.9 1.2 0.12 12.6 0.0 2.3 2 1 1 3 3 3 0 Bacteriophage CII protein Erv26 PF04148.13 OAP54887.1 - 5.1e-88 294.3 0.0 5.9e-88 294.1 0.0 1.0 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 TENA_THI-4 PF03070.16 OAP54888.1 - 9.5e-09 35.4 0.0 8.8e-06 25.7 0.0 2.7 2 1 0 2 2 2 2 TENA/THI-4/PQQC family adh_short PF00106.25 OAP54889.1 - 9.8e-45 152.4 0.0 1.3e-44 152.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP54889.1 - 5.3e-32 111.2 0.0 6.9e-32 110.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP54889.1 - 1.3e-05 25.2 0.0 2.5e-05 24.3 0.0 1.5 1 1 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 OAP54889.1 - 0.081 12.0 0.1 0.18 10.9 0.0 1.6 2 0 0 2 2 2 0 RmlD substrate binding domain zf-H2C2_2 PF13465.6 OAP54890.1 - 4.8e-13 48.9 17.0 1.4e-06 28.4 2.3 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 OAP54890.1 - 1.2e-08 35.0 24.1 0.02 15.3 7.0 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAP54890.1 - 9e-06 26.1 21.1 0.13 13.2 5.6 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 OAP54890.1 - 0.00037 20.4 18.6 0.034 14.1 0.1 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-Di19 PF05605.12 OAP54890.1 - 0.0017 18.6 10.2 0.0026 18.0 6.2 2.3 1 1 1 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-C2HC_2 PF13913.6 OAP54890.1 - 0.014 15.3 0.9 0.014 15.3 0.9 2.2 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Zn-ribbon_8 PF09723.10 OAP54890.1 - 0.03 14.4 1.3 0.03 14.4 1.3 2.5 1 1 2 3 3 3 0 Zinc ribbon domain FYDLN_acid PF09538.10 OAP54890.1 - 0.033 14.8 3.1 0.58 10.9 0.7 3.0 1 1 1 2 2 2 0 Protein of unknown function (FYDLN_acid) zf-C2H2_9 PF16293.5 OAP54890.1 - 0.034 14.0 3.9 2 8.3 0.2 3.2 2 1 1 3 3 3 0 C2H2 type zinc-finger (1 copy) Rad50_zn_hook PF04423.14 OAP54890.1 - 0.049 13.5 7.7 0.16 11.8 0.4 2.8 3 0 0 3 3 3 0 Rad50 zinc hook motif DUF1192 PF06698.11 OAP54890.1 - 0.065 13.3 0.1 0.13 12.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) zf-C2HE PF16278.5 OAP54890.1 - 0.091 13.2 14.1 0.16 12.4 0.7 3.0 1 1 2 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger DUF3450 PF11932.8 OAP54890.1 - 0.11 11.7 5.1 0.17 11.2 5.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DZR PF12773.7 OAP54890.1 - 0.13 12.3 6.7 1.5 8.9 6.5 2.2 1 1 1 2 2 2 0 Double zinc ribbon zf-C2H2_jaz PF12171.8 OAP54890.1 - 0.22 11.8 6.0 1.5 9.2 2.4 3.1 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding CLZ PF16526.5 OAP54890.1 - 0.3 11.5 2.0 0.49 10.8 2.0 1.3 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels zinc_ribbon_9 PF14369.6 OAP54890.1 - 0.54 10.6 2.9 36 4.7 0.1 3.2 3 0 0 3 3 3 0 zinc-ribbon zf-CHCC PF10276.9 OAP54890.1 - 0.57 10.3 4.9 5.5 7.1 0.2 3.1 3 0 0 3 3 3 0 Zinc-finger domain Csm1_N PF18504.1 OAP54890.1 - 0.63 10.4 3.6 1.2 9.5 3.6 1.3 1 0 0 1 1 1 0 Csm1 N-terminal domain Zn_ribbon_SprT PF17283.2 OAP54890.1 - 0.77 9.7 11.6 4.1 7.4 5.0 2.4 2 0 0 2 2 2 0 SprT-like zinc ribbon domain HypA PF01155.19 OAP54890.1 - 0.84 9.7 2.6 2.9 8.0 2.6 1.8 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF3268 PF11672.8 OAP54890.1 - 0.88 9.9 2.7 0.68 10.3 0.6 1.8 1 1 2 3 3 3 0 zinc-finger-containing domain zinc_ribbon_15 PF17032.5 OAP54890.1 - 1.7 9.4 4.3 9.6 7.0 3.4 2.1 1 1 1 2 2 2 0 zinc-ribbon family Zn_Tnp_IS1595 PF12760.7 OAP54890.1 - 1.9 8.5 8.9 12 6.0 4.0 2.5 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-BED PF02892.15 OAP54890.1 - 2.8 8.0 10.2 4.7 7.3 5.3 2.9 2 1 1 3 3 2 0 BED zinc finger zf-C2H2_2 PF12756.7 OAP54890.1 - 4.5 7.7 10.2 2.2 8.7 1.3 3.0 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-ISL3 PF14690.6 OAP54890.1 - 4.6 8.0 9.7 11 6.7 0.3 3.1 3 0 0 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 MOSC PF03473.17 OAP54891.1 - 1.8e-33 115.4 0.1 3.1e-33 114.6 0.1 1.4 1 0 0 1 1 1 1 MOSC domain Aminotran_5 PF00266.19 OAP54891.1 - 2e-22 79.7 0.0 3.1e-22 79.0 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V MOSC_N PF03476.16 OAP54891.1 - 6.2e-20 71.3 0.0 1.3e-19 70.2 0.0 1.6 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain Sugar_tr PF00083.24 OAP54892.1 - 6.3e-71 239.6 22.5 8.3e-71 239.2 22.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP54892.1 - 5e-15 55.3 29.7 8e-11 41.4 19.8 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 OAP54892.1 - 2.8e-06 26.2 13.0 4.1e-05 22.3 0.3 2.4 2 0 0 2 2 2 2 MFS/sugar transport protein DUF4293 PF14126.6 OAP54892.1 - 0.12 12.6 4.1 0.36 11.1 4.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4293) Gate PF07670.14 OAP54892.1 - 0.93 9.8 10.9 13 6.2 3.5 3.4 2 2 1 3 3 3 0 Nucleoside recognition MARVEL PF01284.23 OAP54893.1 - 5.9e-07 29.6 16.2 8e-07 29.2 16.2 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF3367 PF11847.8 OAP54893.1 - 0.11 10.3 0.4 0.15 9.9 0.4 1.1 1 0 0 1 1 1 0 Alpha-(1->3)-arabinofuranosyltransferase UNC-50 PF05216.13 OAP54893.1 - 0.18 11.3 5.6 0.045 13.3 2.1 1.6 2 0 0 2 2 2 0 UNC-50 family DUF4131 PF13567.6 OAP54893.1 - 0.87 9.2 4.6 2.3 7.8 2.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) PLDc_N PF13396.6 OAP54893.1 - 1.3 9.0 8.3 0.44 10.5 0.6 3.7 3 0 0 3 3 3 0 Phospholipase_D-nuclease N-terminal Longin PF13774.6 OAP54895.1 - 0.035 14.1 0.0 0.096 12.7 0.0 1.8 2 0 0 2 2 2 0 Regulated-SNARE-like domain DUF3987 PF13148.6 OAP54895.1 - 0.12 11.3 3.0 0.43 9.5 3.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3987) HMG14_17 PF01101.18 OAP54895.1 - 0.15 13.0 0.0 0.31 12.0 0.0 1.5 1 0 0 1 1 1 0 HMG14 and HMG17 ADH_N PF08240.12 OAP54896.1 - 4.1e-24 84.6 2.1 4.1e-24 84.6 2.1 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAP54896.1 - 3.9e-17 62.4 1.5 6.1e-17 61.8 1.5 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAP54896.1 - 2.1e-05 25.6 0.2 3.6e-05 24.8 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase RuvC PF02075.17 OAP54897.1 - 0.17 11.8 0.3 0.34 10.8 0.3 1.4 1 0 0 1 1 1 0 Crossover junction endodeoxyribonuclease RuvC Sex_peptide PF08138.11 OAP54897.1 - 9.5 6.5 7.5 0.6 10.3 0.1 2.7 2 0 0 2 2 2 0 Sex peptide (SP) family CHCH PF06747.13 OAP54899.1 - 9.3e-05 22.5 7.4 0.00015 21.8 7.4 1.4 1 0 0 1 1 1 1 CHCH domain MTCP1 PF08991.10 OAP54899.1 - 0.0001 22.4 1.3 0.00017 21.7 1.3 1.3 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type GCK PF07802.11 OAP54899.1 - 0.058 13.8 4.9 0.53 10.7 0.4 2.1 1 1 1 2 2 2 0 GCK domain Pet191_N PF10203.9 OAP54899.1 - 0.062 13.6 5.4 0.091 13.1 4.9 1.5 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 NatB_MDM20 PF09797.9 OAP54900.1 - 1.5e-40 139.3 0.0 4.3e-40 137.8 0.0 1.8 1 1 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_19 PF14559.6 OAP54900.1 - 0.026 15.0 0.5 0.31 11.6 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat mRNA_stabil PF13929.6 OAP54900.1 - 0.026 13.5 0.0 0.071 12.1 0.0 1.7 1 0 0 1 1 1 0 mRNA stabilisation Proteasome PF00227.26 OAP54901.1 - 1.9e-41 141.7 0.0 2.2e-41 141.5 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit H_lectin PF09458.10 OAP54901.1 - 0.072 13.3 0.1 0.13 12.4 0.1 1.4 1 0 0 1 1 1 0 H-type lectin domain TUG-UBL1 PF11470.8 OAP54902.1 - 5.1e-26 90.7 0.2 1.5e-25 89.2 0.0 2.0 2 0 0 2 2 2 1 TUG ubiquitin-like domain UBX PF00789.20 OAP54902.1 - 1.6e-05 25.0 0.2 8.3e-05 22.7 0.0 2.4 3 0 0 3 3 3 1 UBX domain RBD PF02196.15 OAP54902.1 - 0.069 13.2 0.0 0.48 10.5 0.0 2.2 2 0 0 2 2 2 0 Raf-like Ras-binding domain PsbP PF01789.16 OAP54902.1 - 0.098 12.8 0.1 0.21 11.7 0.1 1.5 1 0 0 1 1 1 0 PsbP Ribosomal_L38e PF01781.18 OAP54903.1 - 6.2e-30 103.1 3.1 7.6e-30 102.8 3.1 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family Acetyltransf_3 PF13302.7 OAP54904.1 - 6.3e-12 46.3 0.2 4.5e-11 43.6 0.2 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAP54904.1 - 3.6e-05 23.6 0.1 0.033 14.1 0.1 2.3 2 0 0 2 2 2 2 FR47-like protein DNA_pol_E_B PF04042.16 OAP54905.1 - 3.6e-42 144.1 0.0 4.7e-42 143.7 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 OAP54905.1 - 5.2e-42 143.0 0.0 8.5e-42 142.3 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain 4HBT PF03061.22 OAP54907.1 - 2.5e-10 40.6 0.4 4.6e-10 39.7 0.4 1.4 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.6 OAP54907.1 - 0.001 19.2 0.0 0.0014 18.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4442) MaoC_dehydratas PF01575.19 OAP54907.1 - 0.12 11.9 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 MaoC like domain Glyco_transf_25 PF01755.17 OAP54908.1 - 2.3e-10 40.7 1.5 4.1e-08 33.3 0.0 2.8 3 0 0 3 3 3 2 Glycosyltransferase family 25 (LPS biosynthesis protein) DUF3645 PF12359.8 OAP54908.1 - 0.1 12.0 0.2 0.24 10.8 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3645) CAP59_mtransfer PF11735.8 OAP54909.1 - 7.8e-56 189.5 0.0 9.9e-56 189.1 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Glycos_transf_2 PF00535.26 OAP54909.1 - 0.0062 16.4 0.3 0.32 10.8 0.0 2.6 3 0 0 3 3 3 1 Glycosyl transferase family 2 G-patch PF01585.23 OAP54910.1 - 2.2e-05 24.3 0.4 0.00037 20.3 0.0 2.5 2 0 0 2 2 2 1 G-patch domain TFIIF_alpha PF05793.12 OAP54910.1 - 0.092 11.3 20.2 0.12 10.9 20.2 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Menin PF05053.13 OAP54910.1 - 1.2 7.4 12.6 1.6 7.0 12.6 1.1 1 0 0 1 1 1 0 Menin DUF4551 PF15087.6 OAP54910.1 - 7.2 5.3 10.5 9.1 5.0 10.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Mannosyl_trans3 PF11051.8 OAP54911.1 - 2.3e-33 115.7 0.0 3.1e-33 115.3 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative DUF3589 PF12141.8 OAP54912.1 - 4.8e-70 236.5 0.0 1.4e-38 132.8 0.0 2.1 2 0 0 2 2 2 2 Beta-mannosyltransferases Acyl_transf_3 PF01757.22 OAP54913.1 - 2.4e-21 76.2 11.5 5.2e-21 75.1 11.5 1.6 1 1 0 1 1 1 1 Acyltransferase family Pkinase PF00069.25 OAP54914.1 - 1.2e-75 254.3 0.0 2e-75 253.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP54914.1 - 1e-37 129.9 0.0 1.4e-37 129.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 OAP54914.1 - 2.9e-17 62.8 0.1 9.6e-17 61.1 0.1 2.0 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.6 OAP54914.1 - 4e-09 36.2 0.0 1.5e-08 34.3 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 OAP54914.1 - 8e-07 28.2 4.2 1.4e-06 27.3 0.0 2.5 3 0 0 3 3 3 1 Fungal protein kinase Yop-YscD_cpl PF16697.5 OAP54914.1 - 3e-06 27.5 0.0 9.4e-06 25.9 0.0 1.8 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain Kdo PF06293.14 OAP54914.1 - 0.073 12.4 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 OAP54914.1 - 0.13 11.2 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Glyco_transf_25 PF01755.17 OAP54916.1 - 1.7e-07 31.3 0.0 2.3e-06 27.6 0.0 2.1 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) Glyco_transf_34 PF05637.12 OAP54917.1 - 2.4e-11 43.8 0.0 1.4e-05 25.0 0.0 2.3 2 0 0 2 2 2 2 galactosyl transferase GMA12/MNN10 family TPT PF03151.16 OAP54918.1 - 3e-10 39.9 16.5 3.8e-10 39.6 16.5 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 OAP54918.1 - 5.6e-06 26.6 28.6 7.9e-06 26.1 9.6 2.2 2 0 0 2 2 2 2 EamA-like transporter family Stealth_CR2 PF11380.8 OAP54919.1 - 2.5e-16 59.8 2.3 6.4e-16 58.5 1.2 2.3 2 1 0 2 2 2 1 Stealth protein CR2, conserved region 2 Stealth_CR1 PF17101.5 OAP54919.1 - 8.8e-09 35.0 0.1 2.3e-08 33.6 0.1 1.8 1 0 0 1 1 1 1 Stealth protein CR1, conserved region 1 Stealth_CR4 PF17103.5 OAP54919.1 - 0.00046 20.0 0.0 0.001 18.9 0.0 1.6 1 0 0 1 1 1 1 Stealth protein CR4, conserved region 4 Stealth_CR3 PF17102.5 OAP54919.1 - 0.005 16.7 0.1 0.012 15.5 0.1 1.7 1 0 0 1 1 1 1 Stealth protein CR3, conserved region 3 Hid1 PF12722.7 OAP54919.1 - 0.047 11.8 0.6 0.064 11.4 0.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Zip PF02535.22 OAP54919.1 - 0.076 12.2 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter HrcA PF01628.21 OAP54919.1 - 0.17 11.8 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 HrcA protein C terminal domain Ank_2 PF12796.7 OAP54920.1 - 4.1e-34 117.0 0.2 2.1e-18 66.7 0.1 4.7 2 2 3 5 5 5 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OAP54920.1 - 4e-25 87.6 0.8 1.6e-11 44.2 0.1 5.3 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 OAP54920.1 - 4.2e-24 84.6 0.1 3.6e-06 27.4 0.0 6.0 2 2 4 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 OAP54920.1 - 4.4e-24 83.8 4.1 2.4e-06 27.7 0.1 6.1 6 0 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.6 OAP54920.1 - 5e-21 72.5 0.6 3.4e-05 23.9 0.0 7.2 7 0 0 7 7 7 3 Ankyrin repeat CorA PF01544.18 OAP54920.1 - 2e-06 27.3 2.5 0.0002 20.8 0.1 2.4 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein SUR7 PF06687.12 OAP54920.1 - 0.027 14.1 0.0 0.044 13.4 0.0 1.3 1 0 0 1 1 1 0 SUR7/PalI family YgaB PF14182.6 OAP54920.1 - 0.25 11.8 2.0 0.52 10.8 0.7 2.3 2 0 0 2 2 2 0 YgaB-like protein Rx_N PF18052.1 OAP54920.1 - 0.38 11.1 3.7 0.7 10.2 0.1 2.9 3 0 0 3 3 3 0 Rx N-terminal domain PI3_PI4_kinase PF00454.27 OAP54921.1 - 2.4e-38 132.4 0.0 5.9e-36 124.6 0.0 2.6 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 OAP54921.1 - 2.7e-25 88.9 0.1 6.8e-25 87.5 0.1 1.8 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF4135 PF13575.6 OAP54921.1 - 0.085 12.2 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) RAMP4 PF06624.12 OAP54922.1 - 1.3e-17 63.6 0.2 1.5e-17 63.3 0.2 1.1 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 Piezo_RRas_bdg PF12166.8 OAP54922.1 - 0.023 14.0 0.0 0.027 13.8 0.0 1.1 1 0 0 1 1 1 0 Piezo non-specific cation channel, R-Ras-binding domain GAS PF13851.6 OAP54923.1 - 3.6e-05 23.2 41.1 0.0081 15.5 4.1 3.2 1 1 2 3 3 3 3 Growth-arrest specific micro-tubule binding ADIP PF11559.8 OAP54923.1 - 0.0042 17.2 7.5 0.0042 17.2 7.5 3.3 2 1 1 3 3 3 1 Afadin- and alpha -actinin-Binding AAA_13 PF13166.6 OAP54923.1 - 0.013 14.2 26.3 0.018 13.7 26.3 1.1 1 0 0 1 1 1 0 AAA domain bZIP_2 PF07716.15 OAP54923.1 - 0.016 15.3 7.7 0.016 15.3 7.7 4.2 2 2 1 3 3 3 0 Basic region leucine zipper DUF3584 PF12128.8 OAP54923.1 - 0.069 10.7 29.6 0.1 10.1 29.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Filament PF00038.21 OAP54923.1 - 0.53 9.8 36.2 0.53 9.8 33.4 2.3 1 1 1 2 2 2 0 Intermediate filament protein Ax_dynein_light PF10211.9 OAP54923.1 - 1 9.3 38.6 0.15 12.0 10.8 2.8 1 1 1 2 2 2 0 Axonemal dynein light chain Troponin PF00992.20 OAP54923.1 - 3.1 8.1 36.7 0.061 13.6 19.5 2.6 1 1 1 2 2 2 0 Troponin APG6_N PF17675.1 OAP54923.1 - 5.6 7.5 44.8 0.19 12.2 28.4 2.4 1 1 1 2 2 2 0 Apg6 coiled-coil region Spc7 PF08317.11 OAP54923.1 - 6.3 5.6 39.6 8.1 5.2 20.3 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein MmgE_PrpD PF03972.14 OAP54924.1 - 2.8e-124 415.0 12.1 3.3e-124 414.8 12.1 1.0 1 0 0 1 1 1 1 MmgE/PrpD family adh_short_C2 PF13561.6 OAP54925.1 - 1.6e-57 194.8 0.0 2.7e-57 194.0 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP54925.1 - 5.9e-45 153.1 0.3 1.4e-44 151.9 0.3 1.5 1 1 0 1 1 1 1 short chain dehydrogenase P3A PF08727.11 OAP54925.1 - 0.13 11.7 0.1 4.9 6.6 0.0 2.3 2 0 0 2 2 2 0 Poliovirus 3A protein like Sulfatase PF00884.23 OAP54926.1 - 1.4e-45 156.0 0.1 1e-44 153.2 0.1 2.0 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 OAP54926.1 - 8.1e-08 32.2 0.4 3.6e-06 26.8 0.4 2.3 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4976 PF16347.5 OAP54926.1 - 3.4e-05 24.0 0.5 0.00016 21.9 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4976) Sulfatase_C PF14707.6 OAP54926.1 - 0.004 17.9 0.0 0.0082 16.9 0.0 1.5 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase DUF1501 PF07394.12 OAP54926.1 - 0.011 14.8 0.0 0.021 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) DUF229 PF02995.17 OAP54926.1 - 0.12 11.0 0.0 0.15 10.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) DUF1359 PF07097.11 OAP54926.1 - 0.12 12.6 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1359) Sugar_tr PF00083.24 OAP54927.1 - 7.7e-84 282.1 18.5 8.8e-84 281.9 18.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP54927.1 - 1.5e-13 50.5 39.7 1.7e-10 40.4 17.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sulfatase PF00884.23 OAP54928.1 - 3.1e-69 233.7 0.0 3.8e-69 233.4 0.0 1.1 1 0 0 1 1 1 1 Sulfatase DUF229 PF02995.17 OAP54928.1 - 0.0006 18.5 0.0 0.00082 18.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Phosphodiest PF01663.22 OAP54928.1 - 0.0025 17.5 0.0 0.56 9.7 0.0 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4976 PF16347.5 OAP54928.1 - 0.037 14.3 0.0 0.081 13.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4976) Fungal_trans PF04082.18 OAP54929.1 - 4.4e-09 35.8 0.2 7.5e-09 35.0 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Utp13 PF08625.11 OAP54930.1 - 3.7e-48 163.0 0.1 7.6e-48 162.0 0.1 1.5 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain WD40 PF00400.32 OAP54930.1 - 1.6e-46 155.3 21.4 8.7e-05 23.2 0.6 13.5 12 4 0 12 12 12 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAP54930.1 - 6.3e-09 36.0 0.9 14 6.1 0.0 7.6 5 2 2 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OAP54930.1 - 1.1e-05 24.4 10.7 0.73 8.4 0.1 6.2 4 3 2 6 6 6 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 OAP54930.1 - 0.0077 15.2 0.2 1.5 7.7 0.0 3.7 5 0 0 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PALB2_WD40 PF16756.5 OAP54930.1 - 0.081 11.8 1.1 7.6 5.3 0.0 3.8 4 0 0 4 4 4 0 Partner and localizer of BRCA2 WD40 domain Cytochrom_D1 PF02239.16 OAP54930.1 - 0.11 11.0 0.0 0.23 10.0 0.0 1.5 1 0 0 1 1 1 0 Cytochrome D1 heme domain Axin_b-cat_bind PF08833.10 OAP54930.1 - 1.2 9.3 3.5 2 8.6 1.4 2.4 2 0 0 2 2 2 0 Axin beta-catenin binding domain G-patch_2 PF12656.7 OAP54931.1 - 3e-16 59.2 0.3 3e-16 59.2 0.3 2.3 2 0 0 2 2 2 1 G-patch domain CBFNT PF08143.11 OAP54931.1 - 8.5 7.9 10.0 4.6 8.7 0.2 4.0 4 0 0 4 4 4 0 CBFNT (NUC161) domain zf-C3HC4_3 PF13920.6 OAP54932.1 - 4.2e-08 32.9 4.5 4.2e-08 32.9 4.5 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAP54932.1 - 6.4e-08 32.3 5.6 6.4e-08 32.3 5.6 2.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAP54932.1 - 1.1e-07 31.7 4.3 1.1e-07 31.7 4.3 2.2 3 0 0 3 3 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 OAP54932.1 - 2.2e-06 27.7 6.2 2.2e-06 27.7 6.2 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 OAP54932.1 - 2.5e-06 27.7 5.9 2.5e-06 27.7 5.9 2.2 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 OAP54932.1 - 3.1e-06 27.0 6.0 3.1e-06 27.0 6.0 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 OAP54932.1 - 2.4e-05 24.1 8.4 2.4e-05 24.1 8.4 2.6 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OAP54932.1 - 3.2e-05 23.7 1.8 3.2e-05 23.7 1.8 2.4 2 1 0 2 2 2 1 Prokaryotic RING finger family 4 zf-4CXXC_R1 PF10497.9 OAP54932.1 - 0.017 15.4 1.1 0.017 15.4 1.1 2.1 2 0 0 2 2 2 0 Zinc-finger domain of monoamine-oxidase A repressor R1 PHM7_ext PF12621.8 OAP54932.1 - 0.081 13.1 2.8 0.46 10.7 0.9 2.4 2 0 0 2 2 2 0 Extracellular tail, of 10TM putative phosphate transporter DZR PF12773.7 OAP54932.1 - 0.13 12.4 6.5 7.5 6.7 3.2 2.8 2 1 0 2 2 2 0 Double zinc ribbon zf-RING_11 PF17123.5 OAP54932.1 - 1.7 8.4 5.6 5.2 6.9 5.6 1.9 1 0 0 1 1 1 0 RING-like zinc finger IBR PF01485.21 OAP54932.1 - 4.1 7.7 12.8 6 7.2 1.6 3.3 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain zf-rbx1 PF12678.7 OAP54932.1 - 5.5 7.4 11.9 0.16 12.3 4.6 2.2 2 1 0 2 2 1 0 RING-H2 zinc finger domain zinc_ribbon_5 PF13719.6 OAP54932.1 - 5.9 6.7 8.6 1.1 9.1 0.2 2.9 3 0 0 3 3 3 0 zinc-ribbon domain zf-RING_6 PF14835.6 OAP54932.1 - 8.2 6.4 7.1 0.93 9.4 2.1 2.0 2 0 0 2 2 2 0 zf-RING of BARD1-type protein Proteasome PF00227.26 OAP54933.1 - 7.4e-30 103.8 0.0 8.4e-30 103.7 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit WD40 PF00400.32 OAP54934.1 - 4.4e-16 59.0 10.2 3.2e-05 24.6 0.0 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAP54934.1 - 0.0021 18.3 0.0 0.022 15.1 0.0 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Abhydrolase_1 PF00561.20 OAP54936.1 - 8.6e-17 61.6 0.4 1.7e-16 60.6 0.2 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAP54936.1 - 6.3e-15 56.4 3.8 7.7e-15 56.1 3.8 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAP54936.1 - 6.6e-11 41.9 0.8 9.5e-11 41.4 0.8 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 OAP54936.1 - 0.0003 19.8 0.2 0.00055 18.9 0.2 1.5 1 0 0 1 1 1 1 Chlorophyllase enzyme LIDHydrolase PF10230.9 OAP54936.1 - 0.00037 20.1 0.2 0.00055 19.6 0.2 1.2 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Palm_thioest PF02089.15 OAP54936.1 - 0.00041 20.3 0.0 0.0005 20.0 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_5 PF12695.7 OAP54936.1 - 0.00069 19.4 0.0 0.008 16.0 0.1 2.2 2 1 0 2 2 2 1 Alpha/beta hydrolase family Thioesterase PF00975.20 OAP54936.1 - 0.00093 19.4 0.1 0.0017 18.5 0.1 1.4 1 0 0 1 1 1 1 Thioesterase domain UPF0227 PF05728.12 OAP54936.1 - 0.0011 18.9 0.1 0.0032 17.4 0.0 1.8 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0227) Chlorophyllase PF07224.11 OAP54936.1 - 0.0024 17.0 0.9 0.0052 15.9 0.9 1.4 1 1 0 1 1 1 1 Chlorophyllase Esterase PF00756.20 OAP54936.1 - 0.016 14.8 0.0 0.041 13.5 0.0 1.6 2 0 0 2 2 2 0 Putative esterase TetR_C_33 PF13305.6 OAP54936.1 - 0.65 10.8 5.6 1.3 9.8 0.2 3.1 2 1 2 4 4 4 0 Tetracyclin repressor-like, C-terminal domain SAM_2 PF07647.17 OAP54937.1 - 7.7e-09 35.5 0.0 1.4e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 OAP54937.1 - 1e-07 32.2 0.1 2.8e-07 30.9 0.1 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH PF00169.29 OAP54937.1 - 4.2e-07 30.4 0.1 8.1e-07 29.5 0.1 1.5 1 0 0 1 1 1 1 PH domain SAM_3 PF18016.1 OAP54937.1 - 0.0008 19.2 0.0 0.0016 18.2 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) HTH_32 PF13565.6 OAP54937.1 - 0.48 11.1 4.1 3.2 8.4 0.0 3.5 3 0 0 3 3 3 0 Homeodomain-like domain Fungal_trans_2 PF11951.8 OAP54938.1 - 4e-73 246.4 0.8 4.4e-73 246.3 0.0 1.4 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP54938.1 - 1.4e-07 31.5 10.1 2.6e-07 30.6 10.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hydrolase_4 PF12146.8 OAP54940.1 - 2.7e-15 56.3 0.0 2.3e-13 49.9 0.0 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OAP54940.1 - 6.1e-11 43.3 0.0 8.8e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAP54940.1 - 9.4e-11 41.8 1.5 2.3e-08 34.0 0.9 2.4 2 1 0 2 2 2 2 alpha/beta hydrolase fold DLH PF01738.18 OAP54940.1 - 6.6e-05 22.6 0.0 0.099 12.2 0.0 2.8 2 1 1 3 3 3 2 Dienelactone hydrolase family FSH1 PF03959.13 OAP54940.1 - 0.0028 17.4 0.1 0.066 12.9 0.0 2.1 2 0 0 2 2 2 1 Serine hydrolase (FSH1) DUF676 PF05057.14 OAP54940.1 - 0.016 14.7 0.0 0.026 14.0 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.7 OAP54940.1 - 0.074 12.8 0.1 1.2 8.9 0.0 2.3 3 0 0 3 3 3 0 Alpha/beta hydrolase family ANAPC4_WD40 PF12894.7 OAP54941.1 - 8e-07 29.3 0.0 0.046 14.0 0.0 3.7 5 0 0 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OAP54941.1 - 0.00015 22.5 7.9 0.38 11.7 0.2 5.9 5 1 0 5 5 5 1 WD domain, G-beta repeat TFIIF_alpha PF05793.12 OAP54941.1 - 0.84 8.2 9.0 1.2 7.7 9.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) MFS_1 PF07690.16 OAP54942.1 - 1.5e-31 109.6 73.8 4.5e-30 104.8 41.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4083 PF13314.6 OAP54942.1 - 1.3 9.0 2.8 7.1 6.7 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) Fe-ADH PF00465.19 OAP54943.1 - 1e-75 254.9 0.8 1.2e-75 254.7 0.8 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 OAP54943.1 - 4.6e-16 59.3 0.5 6.3e-16 58.8 0.5 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fungal_trans_2 PF11951.8 OAP54944.1 - 0.0051 15.7 2.5 0.43 9.3 0.8 2.0 2 0 0 2 2 2 2 Fungal specific transcription factor domain ILVD_EDD PF00920.21 OAP54944.1 - 0.018 13.7 0.1 0.021 13.5 0.1 1.0 1 0 0 1 1 1 0 Dehydratase family Mlo PF03094.15 OAP54944.1 - 0.064 11.6 0.0 0.075 11.4 0.0 1.1 1 0 0 1 1 1 0 Mlo family Kinocilin PF15033.6 OAP54944.1 - 0.19 11.4 1.8 0.31 10.7 1.5 1.6 1 1 0 1 1 1 0 Kinocilin protein Diphthamide_syn PF01866.17 OAP54945.1 - 2.1e-84 283.6 0.0 2.8e-84 283.1 0.0 1.2 1 0 0 1 1 1 1 Putative diphthamide synthesis protein ComA PF02679.15 OAP54946.1 - 2.3e-92 308.9 0.0 2.7e-92 308.6 0.0 1.0 1 0 0 1 1 1 1 (2R)-phospho-3-sulfolactate synthase (ComA) HMGL-like PF00682.19 OAP54946.1 - 0.1 12.1 0.0 14 5.1 0.0 2.3 1 1 1 2 2 2 0 HMGL-like Oxidored_FMN PF00724.20 OAP54946.1 - 0.18 11.0 0.0 5.4 6.2 0.0 2.1 2 0 0 2 2 2 0 NADH:flavin oxidoreductase / NADH oxidase family PLA2_B PF01735.18 OAP54947.1 - 7.1e-194 644.8 0.7 8.4e-194 644.5 0.7 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain MFS_1 PF07690.16 OAP54948.1 - 5.4e-42 144.0 31.8 5.4e-42 144.0 31.8 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 OAP54948.1 - 2.1e-09 36.4 4.9 4.3e-09 35.4 4.9 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Folate_carrier PF01770.18 OAP54948.1 - 3.6e-06 26.0 1.2 8.2e-06 24.8 1.2 1.5 1 0 0 1 1 1 1 Reduced folate carrier Sugar_tr PF00083.24 OAP54948.1 - 0.00049 19.1 10.5 0.00049 19.1 10.5 2.7 2 2 0 2 2 2 1 Sugar (and other) transporter DUF3902 PF13042.6 OAP54948.1 - 0.038 13.6 4.3 0.017 14.7 1.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3902) ATP-synt_B PF00430.18 OAP54948.1 - 0.22 11.6 0.1 0.39 10.8 0.1 1.3 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) Trp_oprn_chp PF09534.10 OAP54948.1 - 0.52 10.1 4.8 2.5 7.9 2.0 2.5 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Ribophorin_II PF05817.14 OAP54949.1 - 1.2e-29 103.4 1.1 2e-29 102.7 1.1 1.3 1 1 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II Ytp1 PF10355.9 OAP54950.1 - 5.5e-70 235.7 6.2 6.2e-70 235.6 6.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) TetR_C_30 PF17939.1 OAP54950.1 - 0.13 12.5 0.5 0.41 10.9 0.1 2.0 2 1 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain YrhC PF14143.6 OAP54950.1 - 0.37 10.9 0.1 0.37 10.9 0.1 2.8 4 0 0 4 4 4 0 YrhC-like protein Coat_F PF07875.12 OAP54951.1 - 0.094 13.0 0.0 0.3 11.4 0.0 1.9 1 0 0 1 1 1 0 Coat F domain Abhydrolase_1 PF00561.20 OAP54952.1 - 0.00048 19.9 0.0 0.0054 16.4 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAP54952.1 - 0.00054 20.6 0.4 0.00054 20.6 0.4 2.2 1 1 1 2 2 2 1 Alpha/beta hydrolase family BAAT_C PF08840.11 OAP54952.1 - 0.0013 18.7 0.0 0.0022 17.9 0.0 1.3 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_3 PF07859.13 OAP54952.1 - 0.0047 16.8 0.0 0.072 12.9 0.0 2.4 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF1100 PF06500.11 OAP54952.1 - 0.026 13.3 0.0 0.035 12.9 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) DLH PF01738.18 OAP54952.1 - 0.076 12.6 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_5 PF12695.7 OAP54952.1 - 0.077 12.8 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAP54952.1 - 0.092 12.0 0.0 0.2 10.9 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 OAP54952.1 - 0.1 12.1 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Fungal_trans_2 PF11951.8 OAP54953.1 - 4.6e-08 32.3 4.5 9.2e-08 31.3 4.5 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF2336 PF10098.9 OAP54954.1 - 0.072 12.5 0.1 0.11 12.0 0.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2336) 7TM_GPCR_Srh PF10318.9 OAP54955.1 - 0.0025 16.9 3.4 0.0028 16.7 2.0 1.6 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srh TraE PF05309.11 OAP54955.1 - 0.27 10.6 0.1 0.27 10.6 0.1 1.8 2 0 0 2 2 2 0 TraE protein Cation_efflux PF01545.21 OAP54955.1 - 0.94 9.2 10.5 0.25 11.1 6.8 1.9 2 1 0 2 2 2 0 Cation efflux family DUF4044 PF13253.6 OAP54955.1 - 2.3 7.8 9.2 1.2 8.7 0.3 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF4044) MARVEL PF01284.23 OAP54955.1 - 3.6 7.6 11.8 7.2 6.6 11.3 1.9 1 1 0 1 1 1 0 Membrane-associating domain FMO-like PF00743.19 OAP54956.1 - 7.6e-14 51.0 0.4 7.3e-13 47.8 0.1 2.0 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 OAP54956.1 - 5.2e-12 45.6 0.0 6.9e-10 38.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAP54956.1 - 8.7e-12 44.8 0.1 6.9e-10 38.6 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 OAP54956.1 - 1.8e-10 40.9 0.1 3.3e-09 36.8 0.0 2.8 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 OAP54956.1 - 5e-10 39.1 0.0 2e-09 37.1 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAP54956.1 - 0.00023 20.9 6.7 0.0059 16.2 0.1 3.8 2 2 1 4 4 4 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 OAP54956.1 - 0.00079 19.4 0.1 0.76 9.8 0.1 3.8 3 1 0 3 3 3 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 OAP54956.1 - 0.0041 16.2 0.0 0.075 12.1 0.0 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox PF00070.27 OAP54956.1 - 0.0043 17.6 0.1 1.5 9.4 0.1 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAP54956.1 - 0.0064 15.8 0.5 0.021 14.0 0.1 1.9 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 OAP54956.1 - 0.029 13.5 0.0 0.075 12.1 0.0 1.7 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.14 OAP54956.1 - 0.054 12.2 0.3 0.18 10.5 0.1 1.8 2 0 0 2 2 2 0 HI0933-like protein GATase PF00117.28 OAP54957.1 - 2.8e-06 27.2 0.0 4.4e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.19 OAP54957.1 - 0.0047 16.8 0.0 0.0068 16.3 0.0 1.3 1 0 0 1 1 1 1 SNO glutamine amidotransferase family MFS_1 PF07690.16 OAP54958.1 - 6.8e-24 84.4 22.8 6.8e-24 84.4 22.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAP54958.1 - 1.2e-09 37.6 10.3 1.2e-09 37.6 10.3 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter Flavoprotein PF02441.19 OAP54959.1 - 1.2e-24 86.9 0.0 1.5e-24 86.6 0.0 1.1 1 0 0 1 1 1 1 Flavoprotein Fungal_trans PF04082.18 OAP54960.1 - 1.1e-27 96.7 0.4 1.9e-27 96.0 0.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Complex1_LYR PF05347.15 OAP54960.1 - 0.016 15.2 0.0 0.016 15.2 0.0 1.9 2 0 0 2 2 2 0 Complex 1 protein (LYR family) Zn_clus PF00172.18 OAP54960.1 - 0.034 14.3 0.3 0.069 13.3 0.3 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain UbiD PF01977.16 OAP54961.1 - 2.2e-103 346.3 0.0 2.7e-103 346.0 0.0 1.0 1 0 0 1 1 1 1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase Abhydrolase_1 PF00561.20 OAP54962.1 - 1.2e-09 38.2 0.2 3e-08 33.6 0.3 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAP54962.1 - 6.4e-06 26.9 3.7 8e-06 26.6 3.7 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAP54962.1 - 0.0011 18.3 0.0 0.0039 16.5 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 NAD_binding_8 PF13450.6 OAP54962.1 - 0.11 12.7 0.3 1.4 9.2 0.0 2.4 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain DUF4175 PF13779.6 OAP54963.1 - 1.6 6.5 11.7 1.5 6.6 11.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Spt20 PF12090.8 OAP54963.1 - 6.1 6.4 12.5 7.1 6.2 12.5 1.1 1 0 0 1 1 1 0 Spt20 family adh_short PF00106.25 OAP54964.1 - 7e-24 84.4 0.0 9.2e-24 84.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP54964.1 - 4e-21 75.7 0.0 5.1e-21 75.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP54964.1 - 0.0021 18.0 0.0 0.0032 17.4 0.0 1.2 1 0 0 1 1 1 1 KR domain Abhydrolase_3 PF07859.13 OAP54965.1 - 3.9e-53 180.5 0.0 4.9e-53 180.1 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 OAP54965.1 - 9.7e-14 51.1 1.1 4.6e-13 48.9 1.1 1.8 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 OAP54965.1 - 9.3e-06 25.3 0.0 0.12 11.9 0.1 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 OAP54965.1 - 2.8e-05 24.9 1.6 4.9e-05 24.0 1.6 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 OAP54965.1 - 0.018 14.6 0.0 0.2 11.2 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family Say1_Mug180 PF10340.9 OAP54965.1 - 0.057 12.3 0.0 0.092 11.6 0.0 1.5 1 0 0 1 1 1 0 Steryl acetyl hydrolase PALP PF00291.25 OAP54965.1 - 0.089 12.2 0.1 0.14 11.5 0.1 1.2 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme Eno-Rase_NADH_b PF12242.8 OAP54965.1 - 0.17 11.7 0.1 0.33 10.8 0.1 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase adh_short PF00106.25 OAP54966.1 - 7.9e-37 126.6 0.0 1e-36 126.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP54966.1 - 8.5e-27 94.2 0.0 1.1e-26 93.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP54966.1 - 8.3e-06 25.8 0.0 6.3e-05 23.0 0.0 1.9 2 0 0 2 2 2 1 KR domain Methyltransf_25 PF13649.6 OAP54966.1 - 0.023 15.4 0.0 0.057 14.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 OAP54966.1 - 0.055 13.3 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain 4HBT_3 PF13622.6 OAP54968.1 - 1.9e-38 133.2 3.3 2.4e-38 132.8 3.3 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 OAP54968.1 - 1.4e-13 50.8 0.9 8e-10 38.7 0.9 3.3 2 2 1 3 3 3 2 Acyl-CoA thioesterase zf_C2H2_10 PF18414.1 OAP54968.1 - 0.53 9.9 2.5 17 5.0 0.1 2.7 2 0 0 2 2 2 0 C2H2 type zinc-finger Diphthami_syn_2 PF01902.17 OAP54969.1 - 4.9e-16 58.9 0.0 2.4e-09 37.1 0.0 4.0 2 1 0 2 2 2 2 Diphthamide synthase Ribonuc_L-PSP PF01042.21 OAP54969.1 - 6e-12 45.7 0.0 3.1e-06 27.2 0.0 3.6 3 1 0 3 3 3 2 Endoribonuclease L-PSP zf-C2H2 PF00096.26 OAP54970.1 - 1.8e-12 47.0 11.8 2e-06 27.9 0.4 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAP54970.1 - 3.9e-08 33.5 10.0 0.0023 18.6 0.2 3.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OAP54970.1 - 4.5e-07 30.0 12.0 7.1e-07 29.4 4.1 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.8 OAP54970.1 - 4.7e-05 23.6 6.6 0.011 16.1 0.5 3.2 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 OAP54970.1 - 0.00014 21.8 9.5 0.0066 16.4 0.8 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 OAP54970.1 - 0.00062 20.1 8.4 0.0071 16.7 0.3 2.9 3 0 0 3 3 2 2 Zinc-finger of C2H2 type zf_C2H2_ZHX PF18387.1 OAP54970.1 - 0.0039 16.8 3.4 1.1 8.9 0.3 2.8 1 1 1 2 2 2 2 Zinc-fingers and homeoboxes C2H2 finger domain Smg4_UPF3 PF03467.15 OAP54970.1 - 0.0091 16.0 0.8 0.02 15.0 0.8 1.5 1 0 0 1 1 1 1 Smg-4/UPF3 family zf-BED PF02892.15 OAP54970.1 - 0.11 12.6 5.4 0.054 13.5 1.5 2.3 1 1 1 2 2 2 0 BED zinc finger zf-C2H2_3rep PF18868.1 OAP54970.1 - 0.12 13.1 3.3 1.2 9.8 0.7 2.5 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_11 PF16622.5 OAP54970.1 - 0.66 9.8 7.8 9.4 6.1 0.0 2.5 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2HE PF16278.5 OAP54970.1 - 0.83 10.2 7.1 1e+02 3.4 7.1 2.6 1 1 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger zf-LYAR PF08790.11 OAP54970.1 - 1 9.3 5.6 16 5.5 0.1 3.2 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger zf-C2H2_2 PF12756.7 OAP54970.1 - 6.9 7.1 8.9 7.9 6.9 0.4 3.1 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) PITH PF06201.13 OAP54971.1 - 1.2e-39 135.9 0.1 2.2e-39 135.1 0.1 1.4 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.20 OAP54971.1 - 2.4e-26 91.7 0.0 4.6e-26 90.8 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 OAP54971.1 - 1.3e-07 31.3 0.0 4.5e-07 29.5 0.0 1.8 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 OAP54971.1 - 2.2e-06 28.1 0.0 6.3e-06 26.6 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 OAP54971.1 - 6.4e-05 23.2 0.0 0.0013 19.0 0.0 2.3 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_9 PF14595.6 OAP54971.1 - 0.00056 19.7 0.0 0.00094 19.0 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 OAP54971.1 - 0.0095 15.8 0.1 0.15 12.0 0.1 2.2 1 1 1 2 2 2 1 AhpC/TSA family Redoxin PF08534.10 OAP54971.1 - 0.02 14.6 0.0 1.7 8.3 0.0 2.3 1 1 1 2 2 2 0 Redoxin Thioredoxin_7 PF13899.6 OAP54971.1 - 0.1 12.8 0.0 0.23 11.7 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like Fungal_trans_2 PF11951.8 OAP54972.1 - 2.5e-08 33.1 4.2 1.3e-05 24.2 0.3 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain C2 PF00168.30 OAP54973.1 - 7.8e-23 80.7 0.0 7e-12 45.5 0.0 2.5 2 0 0 2 2 2 2 C2 domain zf-CSL PF05207.13 OAP54974.1 - 7.8e-20 70.4 1.5 1.3e-19 69.6 1.5 1.4 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.31 OAP54974.1 - 3e-13 49.7 2.2 2.3e-12 46.8 2.2 2.1 1 1 0 1 1 1 1 DnaJ domain DAGAT PF03982.13 OAP54976.1 - 1.4e-89 300.0 0.0 1.7e-89 299.7 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Asp PF00026.23 OAP54977.1 - 4.3e-77 259.6 11.1 5.2e-77 259.3 11.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OAP54977.1 - 4.2e-09 36.9 3.0 0.0025 18.1 1.2 3.0 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 OAP54977.1 - 8.9e-07 29.5 1.1 0.00013 22.6 0.2 2.8 2 1 0 2 2 2 2 Aspartyl protease HMG_box PF00505.19 OAP54979.1 - 1.7e-14 54.0 0.1 1.7e-14 54.0 0.1 1.9 2 0 0 2 2 2 1 HMG (high mobility group) box SAM_1 PF00536.30 OAP54979.1 - 6.9e-11 42.4 0.0 1.2e-10 41.6 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) HMG_box_2 PF09011.10 OAP54979.1 - 2.5e-08 34.4 0.3 2.5e-08 34.4 0.3 1.8 2 0 0 2 2 2 1 HMG-box domain SAM_2 PF07647.17 OAP54979.1 - 1e-05 25.6 0.0 1.7e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SUIM_assoc PF16619.5 OAP54979.1 - 0.015 15.3 0.2 0.053 13.6 0.2 1.9 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 NCD1 PF04904.13 OAP54979.1 - 0.054 13.5 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 NAB conserved region 1 (NCD1) CLZ PF16526.5 OAP54980.1 - 0.022 15.1 0.4 0.022 15.1 0.4 1.4 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Lzipper-MIP1 PF14389.6 OAP54980.1 - 0.026 14.8 0.2 0.04 14.2 0.2 1.3 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 Allexi_40kDa PF05549.11 OAP54980.1 - 0.045 13.3 1.2 0.049 13.1 1.2 1.1 1 0 0 1 1 1 0 Allexivirus 40kDa protein UPF0184 PF03670.13 OAP54980.1 - 0.046 14.1 0.6 0.053 13.9 0.6 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) APG6_N PF17675.1 OAP54980.1 - 0.091 13.3 3.4 0.099 13.2 3.4 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region IF-2B PF01008.17 OAP54981.1 - 4.7e-75 252.4 0.6 5.5e-75 252.2 0.6 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family Methyltransf_25 PF13649.6 OAP54982.1 - 1.4e-11 44.9 0.0 2.5e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAP54982.1 - 3.2e-11 43.7 0.0 5.1e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAP54982.1 - 0.00043 20.1 0.0 0.0006 19.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAP54982.1 - 0.0011 18.3 0.0 0.0027 17.1 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 OAP54982.1 - 0.0017 19.1 0.0 0.0032 18.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.12 OAP54982.1 - 0.0019 17.4 0.0 0.0029 16.8 0.0 1.3 1 0 0 1 1 1 1 DREV methyltransferase FtsJ PF01728.19 OAP54982.1 - 0.0027 17.8 0.0 0.0034 17.5 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.6 OAP54982.1 - 0.01 15.7 0.0 0.022 14.6 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.20 OAP54982.1 - 0.066 12.3 0.0 0.088 11.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_4 PF02390.17 OAP54982.1 - 0.15 11.5 0.0 21 4.5 0.0 3.0 3 0 0 3 3 3 0 Putative methyltransferase LSM PF01423.22 OAP54983.1 - 3.2e-17 62.0 0.0 4.4e-17 61.5 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 OAP54983.1 - 0.0018 18.4 0.1 0.0025 17.9 0.1 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 OAP54983.1 - 0.0092 16.1 0.0 0.01 15.9 0.0 1.2 1 0 0 1 1 1 1 Scd6-like Sm domain Methyltransf_23 PF13489.6 OAP54984.1 - 5.1e-21 75.2 0.0 7.3e-21 74.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAP54984.1 - 8.7e-12 45.6 0.0 1.7e-11 44.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAP54984.1 - 3.3e-08 34.1 0.0 6e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAP54984.1 - 1.2e-06 28.4 0.0 2.4e-05 24.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 OAP54984.1 - 2e-05 24.1 0.0 4.4e-05 22.9 0.0 1.6 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 OAP54984.1 - 2e-05 25.2 0.0 0.00012 22.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 OAP54984.1 - 0.006 15.9 0.0 0.0088 15.4 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain PrmA PF06325.13 OAP54984.1 - 0.057 12.8 0.0 0.098 12.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.17 OAP54984.1 - 0.079 12.4 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase MTS PF05175.14 OAP54984.1 - 0.24 10.9 0.0 0.51 9.9 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase small domain p450 PF00067.22 OAP54985.1 - 3.6e-44 151.3 0.0 4.8e-44 150.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 OmdA PF13376.6 OAP54987.1 - 8.1e-14 51.4 3.8 3e-13 49.6 0.0 2.4 2 0 0 2 2 2 1 Bacteriocin-protection, YdeI or OmpD-Associated FAD_binding_3 PF01494.19 OAP54988.1 - 8.3e-11 41.7 0.7 6.7e-09 35.4 0.3 2.9 2 1 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 OAP54988.1 - 0.00074 18.8 0.0 0.0081 15.4 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAP54988.1 - 0.0015 18.2 0.1 0.043 13.4 0.1 2.4 2 1 1 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAP54988.1 - 0.0015 18.7 0.0 0.0036 17.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 OAP54988.1 - 0.013 16.1 0.0 0.045 14.3 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Peptidase_S9 PF00326.21 OAP54988.1 - 0.052 13.0 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Rad60-SLD PF11976.8 OAP54989.1 - 7.3e-16 57.8 0.4 3.7e-13 49.1 0.2 2.5 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 OAP54989.1 - 1.9e-07 30.7 1.5 1e-06 28.4 0.0 2.7 3 0 0 3 3 3 1 Ubiquitin family Ribosomal_L36e PF01158.18 OAP54990.1 - 1.5e-42 143.7 5.7 1.8e-42 143.5 5.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e MRP-L28 PF09812.9 OAP54990.1 - 0.019 15.1 1.8 0.023 14.8 1.8 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L28 PBS_linker_poly PF00427.21 OAP54990.1 - 0.039 14.0 0.1 0.043 13.9 0.1 1.1 1 0 0 1 1 1 0 Phycobilisome Linker polypeptide DUF2207 PF09972.9 OAP54990.1 - 0.15 10.8 0.0 0.15 10.8 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) M20_dimer PF07687.14 OAP54991.1 - 8.2e-16 57.9 0.0 1.6e-15 57.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 OAP54991.1 - 1.6e-13 50.8 0.1 4.9e-12 46.0 0.1 2.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.17 OAP54991.1 - 0.00023 20.9 0.0 0.00039 20.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 UCH PF00443.29 OAP54992.1 - 2.5e-22 79.6 0.0 5.5e-22 78.5 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 OAP54992.1 - 1.7e-12 47.4 0.3 3e-12 46.7 0.3 1.4 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 OAP54992.1 - 0.12 12.0 0.0 0.24 11.0 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Cpn60_TCP1 PF00118.24 OAP54994.1 - 1.6e-143 478.9 8.7 1.9e-143 478.7 8.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family CRM1_repeat PF18777.1 OAP54994.1 - 0.096 12.2 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Chromosome region maintenance or exportin repeat Pkinase PF00069.25 OAP54995.1 - 5.1e-37 127.7 0.0 5.9e-35 120.9 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Ribonuc_2-5A PF06479.12 OAP54995.1 - 4.1e-31 107.8 0.1 1.3e-30 106.2 0.0 1.9 2 0 0 2 2 2 1 Ribonuclease 2-5A Pkinase_Tyr PF07714.17 OAP54995.1 - 1.7e-16 60.3 0.0 3.4e-15 56.0 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase PQQ PF01011.21 OAP54995.1 - 2.2e-05 24.2 0.0 0.0022 17.8 0.0 3.0 3 0 0 3 3 3 1 PQQ enzyme repeat PQQ_2 PF13360.6 OAP54995.1 - 0.031 13.9 0.0 0.098 12.2 0.0 1.8 1 1 0 1 1 1 0 PQQ-like domain Kdo PF06293.14 OAP54995.1 - 0.045 13.1 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OAP54995.1 - 0.055 12.2 2.0 0.15 10.8 2.0 1.7 1 1 0 1 1 1 0 Fungal protein kinase APH PF01636.23 OAP54995.1 - 0.082 12.8 0.0 1.4 8.8 0.0 2.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family NAM-associated PF14303.6 OAP54995.1 - 5.2 7.8 10.1 25 5.5 0.0 2.4 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain zf-LYAR PF08790.11 OAP54996.1 - 1.2e-15 57.1 5.3 3e-15 55.8 5.3 1.8 1 0 0 1 1 1 1 LYAR-type C2HC zinc finger GAGE PF05831.11 OAP54996.1 - 0.3 11.7 9.0 0.65 10.6 1.9 3.1 3 0 0 3 3 3 0 GAGE protein HD PF01966.22 OAP54997.1 - 1.5e-08 34.9 0.5 2.5e-08 34.2 0.5 1.3 1 0 0 1 1 1 1 HD domain Cyclase PF04199.13 OAP54997.1 - 0.13 12.5 0.1 0.61 10.3 0.0 2.0 1 1 1 2 2 2 0 Putative cyclase INSIG PF07281.12 OAP54998.1 - 5.9e-66 222.1 2.3 7.8e-66 221.7 2.3 1.2 1 0 0 1 1 1 1 Insulin-induced protein (INSIG) ECH_1 PF00378.20 OAP54999.1 - 2.5e-44 151.5 0.0 3.8e-44 150.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase HMGL-like PF00682.19 OAP54999.1 - 6.4e-40 137.4 0.0 8.9e-40 136.9 0.0 1.2 1 0 0 1 1 1 1 HMGL-like ECH_2 PF16113.5 OAP54999.1 - 8.2e-26 91.3 0.0 1.2e-25 90.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase AMP-binding PF00501.28 OAP55000.1 - 3.1e-93 312.7 0.1 6.7e-93 311.6 0.1 1.5 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAP55000.1 - 6.1e-12 46.3 0.0 1.9e-11 44.8 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Carboxyl_trans PF01039.22 OAP55001.1 - 1.7e-116 389.8 0.0 2.1e-116 389.5 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain Fungal_trans PF04082.18 OAP55002.1 - 1e-25 90.3 0.2 2.7e-25 88.9 0.0 1.7 1 1 1 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP55002.1 - 4.5e-08 33.1 10.1 1.2e-07 31.7 10.1 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acyl-CoA_dh_1 PF00441.24 OAP55003.1 - 7.7e-31 107.3 0.3 1.7e-30 106.2 0.3 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 OAP55003.1 - 2e-22 80.0 0.0 1.5e-21 77.2 0.0 2.5 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 OAP55003.1 - 5.7e-22 77.7 0.0 9.2e-22 77.1 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 OAP55003.1 - 0.0061 16.8 0.9 0.014 15.7 0.9 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain CPSase_L_D2 PF02786.17 OAP55004.1 - 1.8e-68 230.2 0.0 2.7e-68 229.6 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 OAP55004.1 - 4.4e-41 139.9 0.0 9.4e-41 138.8 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 OAP55004.1 - 2.4e-32 111.2 0.0 4.6e-32 110.3 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Dala_Dala_lig_C PF07478.13 OAP55004.1 - 2e-10 40.6 0.0 4.4e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl PF00364.22 OAP55004.1 - 5.3e-10 39.0 2.2 2.5e-09 36.8 1.9 2.2 1 1 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp PF02222.22 OAP55004.1 - 2.1e-09 37.2 0.1 4.6e-09 36.1 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 OAP55004.1 - 1.2e-07 31.9 0.0 2.2e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 OAP55004.1 - 0.0093 15.8 0.1 0.077 12.8 0.0 2.3 2 0 0 2 2 2 1 Biotin-lipoyl like hSH3 PF14603.6 OAP55004.1 - 0.018 15.4 0.1 0.043 14.2 0.1 1.6 1 0 0 1 1 1 0 Helically-extended SH3 domain ATPgrasp_YheCD PF14398.6 OAP55004.1 - 0.051 12.8 0.0 1.3 8.2 0.0 2.2 2 0 0 2 2 2 0 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 OAP55004.1 - 0.083 12.1 0.0 0.19 11.0 0.0 1.5 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp Polysacc_synt_4 PF04669.13 OAP55005.1 - 2.3e-20 72.9 0.1 2.1e-18 66.6 0.1 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis ABC_membrane PF00664.23 OAP55006.1 - 2.7e-75 253.5 27.1 3.7e-44 151.4 6.0 2.9 2 1 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 OAP55006.1 - 5.9e-60 201.7 0.0 1.2e-29 103.6 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 OAP55006.1 - 2.3e-17 63.2 2.2 8.4e-07 28.6 0.0 4.5 4 0 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 OAP55006.1 - 2.6e-09 36.7 0.4 0.0026 17.5 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 OAP55006.1 - 3.5e-08 33.8 0.3 0.084 13.1 0.0 4.3 3 1 0 3 3 3 2 AAA domain ABC_ATPase PF09818.9 OAP55006.1 - 4e-08 32.5 5.7 0.001 18.0 0.1 4.3 4 1 0 4 4 4 2 Predicted ATPase of the ABC class AAA_25 PF13481.6 OAP55006.1 - 1.6e-06 27.8 3.0 0.88 9.1 0.0 3.5 3 0 0 3 3 3 3 AAA domain RsgA_GTPase PF03193.16 OAP55006.1 - 1.6e-06 28.1 0.0 0.1 12.5 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 OAP55006.1 - 2.6e-06 27.9 4.2 0.018 15.4 0.5 3.3 3 1 0 3 3 2 2 AAA ATPase domain AAA_21 PF13304.6 OAP55006.1 - 8.6e-06 25.8 0.1 0.83 9.4 0.0 4.0 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.6 OAP55006.1 - 9.7e-05 22.6 0.1 0.24 11.6 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 OAP55006.1 - 0.00033 21.2 0.5 0.96 9.9 0.1 2.4 2 0 0 2 2 2 2 AAA domain cobW PF02492.19 OAP55006.1 - 0.0008 19.0 0.4 2.9 7.5 0.0 3.4 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 OAP55006.1 - 0.0012 19.4 0.0 1.1 9.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 OAP55006.1 - 0.0014 18.4 1.2 5.3 6.7 0.0 3.8 4 0 0 4 4 4 0 AAA domain DUF3987 PF13148.6 OAP55006.1 - 0.0017 17.4 0.0 0.65 9.0 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3987) AAA_15 PF13175.6 OAP55006.1 - 0.0025 17.6 0.0 0.76 9.4 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain CobA_CobO_BtuR PF02572.15 OAP55006.1 - 0.0029 17.9 3.0 0.21 11.9 0.2 3.1 3 0 0 3 3 3 1 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP FtsK_SpoIIIE PF01580.18 OAP55006.1 - 0.0031 16.9 0.0 0.75 9.1 0.0 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family ATP-synt_ab PF00006.25 OAP55006.1 - 0.0032 17.1 0.0 1.2 8.8 0.0 2.9 2 1 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain ATPase PF06745.13 OAP55006.1 - 0.0039 16.6 3.3 1.7 7.9 0.0 3.2 3 0 0 3 3 3 2 KaiC MMR_HSR1 PF01926.23 OAP55006.1 - 0.0044 17.1 0.1 5.2 7.2 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_7 PF12775.7 OAP55006.1 - 0.0054 16.3 0.0 3.2 7.2 0.0 2.9 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_24 PF13479.6 OAP55006.1 - 0.0063 16.3 0.1 3 7.5 0.0 2.8 3 0 0 3 3 3 1 AAA domain DUF87 PF01935.17 OAP55006.1 - 0.0067 16.6 6.4 0.36 10.9 1.3 3.1 4 0 0 4 4 3 1 Helicase HerA, central domain SbcCD_C PF13558.6 OAP55006.1 - 0.0071 16.6 0.8 5.5 7.3 0.0 3.5 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit DEAD PF00270.29 OAP55006.1 - 0.0085 15.9 0.2 5.4 6.7 0.0 3.8 3 1 0 3 3 3 0 DEAD/DEAH box helicase Zeta_toxin PF06414.12 OAP55006.1 - 0.021 14.1 0.1 1.5 8.0 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin Mg_chelatase PF01078.21 OAP55006.1 - 0.023 14.1 0.3 4.9 6.5 0.0 2.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 OAP55006.1 - 0.026 14.4 1.6 3.7 7.4 0.0 3.0 2 0 0 2 2 2 0 NACHT domain RNA_helicase PF00910.22 OAP55006.1 - 0.038 14.4 0.1 3.8 7.9 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_5 PF07728.14 OAP55006.1 - 0.068 13.2 0.1 24 4.9 0.0 2.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Ploopntkinase3 PF18751.1 OAP55006.1 - 0.078 12.9 0.2 4.6 7.1 0.0 2.6 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 APS_kinase PF01583.20 OAP55006.1 - 0.15 12.0 0.7 5.4 6.9 0.0 3.0 3 0 0 3 3 3 0 Adenylylsulphate kinase G-alpha PF00503.20 OAP55006.1 - 0.16 11.1 0.0 8.8 5.4 0.0 2.3 2 0 0 2 2 2 0 G-protein alpha subunit ATP_bind_1 PF03029.17 OAP55006.1 - 0.16 11.7 0.5 21 4.8 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein CbiA PF01656.23 OAP55006.1 - 0.21 11.7 2.4 2.2 8.4 0.0 2.7 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_17 PF13207.6 OAP55006.1 - 0.26 11.7 0.7 68 3.9 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA_28 PF13521.6 OAP55006.1 - 0.64 10.2 2.7 17 5.6 0.6 3.3 3 0 0 3 3 2 0 AAA domain DUF3328 PF11807.8 OAP55007.1 - 1.3e-18 67.6 0.1 1.9e-18 67.1 0.0 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) Pro_isomerase PF00160.21 OAP55008.1 - 5.3e-51 173.0 0.1 1.2e-50 171.9 0.1 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 OAP55008.1 - 1.1e-06 29.3 0.1 0.021 15.7 0.0 4.3 4 0 0 4 4 4 1 WD domain, G-beta repeat Cytokin_check_N PF10407.9 OAP55009.1 - 0.017 15.0 0.1 0.036 14.0 0.1 1.5 1 0 0 1 1 1 0 Cdc14 phosphatase binding protein N-terminus eIF2_C PF09173.11 OAP55010.1 - 4.7e-34 116.5 0.3 1.1e-33 115.4 0.3 1.6 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 OAP55010.1 - 8.3e-23 80.9 0.2 6.1e-22 78.1 0.2 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 OAP55010.1 - 1.5e-11 44.6 0.6 3.1e-11 43.5 0.6 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RsgA_GTPase PF03193.16 OAP55010.1 - 0.0036 17.2 0.1 0.031 14.2 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 OAP55010.1 - 0.0049 16.9 0.0 0.0097 16.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 OAP55010.1 - 0.14 12.2 0.0 0.52 10.4 0.0 2.0 3 0 0 3 3 3 0 Dynamin family MMR_HSR1_Xtn PF16897.5 OAP55010.1 - 0.15 12.1 0.1 0.3 11.1 0.1 1.5 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain adh_short_C2 PF13561.6 OAP55011.1 - 1.6e-41 142.4 2.8 2e-41 142.1 2.8 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP55011.1 - 1.8e-35 122.2 2.4 2.3e-35 121.8 2.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAP55011.1 - 6.9e-13 48.9 3.1 9.3e-13 48.5 3.1 1.1 1 0 0 1 1 1 1 KR domain FAD_binding_2 PF00890.24 OAP55012.1 - 7.4e-62 209.8 0.3 7.4e-62 209.8 0.3 2.0 2 1 0 2 2 2 1 FAD binding domain DAO PF01266.24 OAP55012.1 - 5.8e-11 42.6 6.8 2e-10 40.8 6.8 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 OAP55012.1 - 6e-11 41.7 2.4 1.2e-08 34.1 1.5 2.9 2 1 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 OAP55012.1 - 3.6e-09 36.5 0.6 5.7e-09 35.8 0.6 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Fungal_trans PF04082.18 OAP55012.1 - 3.7e-07 29.4 0.0 7.2e-07 28.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pyr_redox_2 PF07992.14 OAP55012.1 - 3.2e-06 26.6 1.8 0.00024 20.5 0.9 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OAP55012.1 - 2.8e-05 23.4 2.3 2.8e-05 23.4 2.3 2.9 3 1 0 3 3 3 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 OAP55012.1 - 8.4e-05 22.7 2.7 0.00031 20.9 2.7 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 OAP55012.1 - 0.00053 19.3 3.0 0.00064 19.0 0.8 2.0 2 0 0 2 2 2 1 Thi4 family AlaDh_PNT_C PF01262.21 OAP55012.1 - 0.0045 16.3 0.9 0.0093 15.3 0.9 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 OAP55012.1 - 0.0067 17.0 2.4 0.36 11.4 2.3 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 OAP55012.1 - 0.079 12.2 2.0 0.14 11.4 2.0 1.4 1 0 0 1 1 1 0 FAD binding domain Amino_oxidase PF01593.24 OAP55012.1 - 0.32 10.2 2.3 15 4.7 0.9 2.4 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 OAP55012.1 - 0.8 8.7 2.3 1.6 7.7 2.3 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 OAP55012.1 - 0.95 8.7 4.8 0.78 8.9 3.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAA_hydrolase PF01557.18 OAP55013.1 - 4e-59 199.9 0.0 4.9e-59 199.6 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family MFS_1 PF07690.16 OAP55014.1 - 3.7e-28 98.5 25.5 3.7e-28 98.5 25.5 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAP55014.1 - 0.00065 18.7 9.3 0.00065 18.7 9.3 3.0 3 0 0 3 3 3 2 Sugar (and other) transporter Pyr_redox_3 PF13738.6 OAP55015.1 - 5.5e-18 65.3 0.1 2.9e-17 62.9 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAP55015.1 - 6.4e-16 58.4 0.0 4.2e-13 49.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 OAP55015.1 - 4.7e-12 45.1 0.0 1.1e-11 43.9 0.0 1.6 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 OAP55015.1 - 1.5e-08 34.2 0.1 7.2e-07 28.7 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 OAP55015.1 - 7.8e-08 32.8 0.0 0.02 15.5 0.0 3.0 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 OAP55015.1 - 4.3e-06 26.2 0.2 6.4e-05 22.4 0.3 2.5 1 1 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 OAP55015.1 - 8.4e-06 25.9 0.9 4.2e-05 23.7 0.0 2.6 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAP55015.1 - 1.1e-05 25.2 0.0 0.0091 15.6 0.0 2.6 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 OAP55015.1 - 0.0033 17.8 0.0 1.3 9.5 0.0 2.5 2 0 0 2 2 2 1 Putative NAD(P)-binding Thi4 PF01946.17 OAP55015.1 - 0.0038 16.5 0.0 0.019 14.2 0.0 1.9 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 OAP55015.1 - 0.014 14.5 0.5 0.031 13.4 0.1 1.8 2 0 0 2 2 2 0 FAD binding domain NAD_binding_9 PF13454.6 OAP55015.1 - 0.02 14.9 0.0 0.48 10.4 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding HicA_toxin PF07927.12 OAP55015.1 - 0.033 14.2 0.6 7.9 6.6 0.1 2.6 2 0 0 2 2 2 0 HicA toxin of bacterial toxin-antitoxin, HI0933_like PF03486.14 OAP55015.1 - 0.06 12.0 0.0 0.16 10.7 0.0 1.7 2 0 0 2 2 2 0 HI0933-like protein 2-Hacid_dh_C PF02826.19 OAP55015.1 - 0.063 12.6 0.0 1.5 8.2 0.0 2.3 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 OAP55015.1 - 0.074 12.1 0.0 0.98 8.4 0.0 2.4 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_2 PF03446.15 OAP55016.1 - 5.3e-27 94.9 0.4 8.8e-27 94.2 0.4 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 OAP55016.1 - 1.4e-10 41.4 0.1 3e-10 40.4 0.1 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 OAP55016.1 - 4.9e-09 36.7 1.6 1.1e-08 35.5 0.1 2.3 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent UDPG_MGDP_dh_N PF03721.14 OAP55016.1 - 0.0059 16.2 1.0 0.019 14.5 0.4 2.0 1 1 1 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Sacchrp_dh_NADP PF03435.18 OAP55016.1 - 0.012 15.9 1.0 0.05 13.9 0.2 2.3 2 1 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 OAP55016.1 - 0.018 15.5 0.1 0.032 14.7 0.1 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 OAP55016.1 - 0.043 13.8 0.7 0.32 11.0 0.7 2.1 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GFO_IDH_MocA PF01408.22 OAP55016.1 - 0.057 14.3 0.1 0.15 12.9 0.1 1.7 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Nuc_deoxyri_tr2 PF15891.5 OAP55016.1 - 0.15 12.4 0.0 0.31 11.4 0.0 1.5 1 0 0 1 1 1 0 Nucleoside 2-deoxyribosyltransferase like adh_short_C2 PF13561.6 OAP55017.1 - 4.4e-39 134.4 0.0 5.5e-39 134.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP55017.1 - 1.4e-35 122.5 0.0 2.6e-35 121.7 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAP55017.1 - 0.0036 17.2 0.0 0.0051 16.8 0.0 1.2 1 0 0 1 1 1 1 KR domain ILVD_EDD PF00920.21 OAP55018.1 - 8.5e-151 503.1 0.0 9.9e-151 502.9 0.0 1.0 1 0 0 1 1 1 1 Dehydratase family DUF1611_N PF17396.2 OAP55018.1 - 0.02 15.1 0.0 1.3 9.3 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1611_N) Rossmann-like domain SHOCT PF09851.9 OAP55018.1 - 4 7.3 8.5 0.11 12.2 0.5 2.6 3 0 0 3 3 3 0 Short C-terminal domain MRP-L27 PF09809.9 OAP55019.1 - 6e-10 39.0 0.0 1.8e-09 37.4 0.0 1.8 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 DUF3864 PF12980.7 OAP55019.1 - 0.0017 18.6 1.3 0.0037 17.5 0.5 2.0 1 1 1 2 2 2 1 Domain of Unknown Function with PDB structure (DUF3864) TFIIA PF03153.13 OAP55019.1 - 0.033 14.2 19.4 0.037 14.0 19.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.9 OAP55019.1 - 0.71 8.1 18.6 0.86 7.8 18.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Hydin_ADK PF17213.3 OAP55019.1 - 5.2 7.3 11.2 7.2 6.8 11.2 1.2 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Glyco_hydro81C PF17652.1 OAP55021.1 - 1e-161 538.0 7.4 1.3e-161 537.6 7.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 OAP55021.1 - 3.4e-109 364.9 1.4 6.2e-109 364.1 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 81 N-terminal domain Peptidase_S21 PF00716.17 OAP55021.1 - 0.094 12.4 3.3 0.16 11.6 3.3 1.4 1 0 0 1 1 1 0 Assemblin (Peptidase family S21) Utp14 PF04615.13 OAP55022.1 - 1.8e-172 575.8 53.4 1.8e-172 575.8 53.4 2.7 1 1 1 2 2 2 1 Utp14 protein APH PF01636.23 OAP55023.1 - 7.1e-15 55.6 0.1 1.1e-14 55.0 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 OAP55023.1 - 0.00056 19.6 0.0 0.00097 18.8 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.20 OAP55023.1 - 0.0013 18.1 0.0 0.0018 17.6 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase Pkinase_Tyr PF07714.17 OAP55023.1 - 0.037 13.3 0.0 0.059 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Haspin_kinase PF12330.8 OAP55023.1 - 0.11 11.4 0.0 0.35 9.8 0.0 1.7 1 1 1 2 2 2 0 Haspin like kinase domain Ank_2 PF12796.7 OAP55025.1 - 1e-13 51.7 0.6 1e-05 26.0 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAP55025.1 - 1.1e-12 48.2 0.8 1.2e-07 32.2 0.2 4.9 3 2 2 5 5 5 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 OAP55025.1 - 1.7e-11 44.1 0.1 0.0001 22.5 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAP55025.1 - 4.7e-09 35.8 0.1 0.034 14.7 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 OAP55025.1 - 0.00014 22.1 0.8 0.99 10.0 0.0 4.2 4 0 0 4 4 4 1 Ankyrin repeat KilA-N PF04383.13 OAP55025.1 - 0.001 18.9 0.5 0.02 14.7 0.5 2.4 1 1 0 1 1 1 1 KilA-N domain Sec8_exocyst PF04048.14 OAP55025.1 - 0.14 12.1 3.6 0.068 13.1 1.1 1.7 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain DUF349 PF03993.12 OAP55025.1 - 0.61 10.4 6.8 2.2 8.6 6.8 2.1 1 1 0 1 1 1 0 Domain of Unknown Function (DUF349) CREPT PF16566.5 OAP55025.1 - 0.83 9.8 8.1 0.078 13.1 2.8 2.0 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour Rab_bind PF16704.5 OAP55025.1 - 1.8 8.7 5.3 5.3 7.2 1.3 2.6 1 1 1 2 2 2 0 Rab binding domain OmpH PF03938.14 OAP55025.1 - 2.1 8.7 11.9 5.5 7.3 7.8 2.7 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Phage_GPO PF05929.11 OAP55025.1 - 3.2 7.3 8.1 0.6 9.7 4.3 1.6 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase COX16 PF14138.6 OAP55025.1 - 4.8 7.8 6.2 2.1 8.9 0.2 2.5 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein COX16 DUF4559 PF15112.6 OAP55025.1 - 4.9 6.7 7.7 0.55 9.9 1.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4559) PIN_8 PF18476.1 OAP55025.1 - 7.3 6.4 7.9 7.9 6.3 3.1 2.3 2 0 0 2 2 2 0 PIN like domain RisS_PPD PF16524.5 OAP55026.1 - 0.12 12.6 0.0 13 6.1 0.0 2.3 2 0 0 2 2 2 0 Periplasmic domain of Sensor histidine kinase RisS Gp_dh_N PF00044.24 OAP55026.1 - 0.14 12.5 0.3 26 5.2 0.1 3.0 2 1 1 3 3 3 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain TPR_1 PF00515.28 OAP55027.1 - 1.1e-06 28.2 0.0 0.23 11.3 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 OAP55027.1 - 0.00011 22.3 0.2 0.17 12.4 0.0 4.5 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 OAP55027.1 - 0.00011 22.0 9.2 0.5 10.6 0.1 5.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 OAP55027.1 - 0.0054 16.4 0.0 0.7 9.6 0.0 3.1 2 1 1 3 3 3 1 TPR repeat TPR_7 PF13176.6 OAP55027.1 - 0.0071 16.3 4.5 1.5 9.0 0.1 4.4 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 OAP55027.1 - 0.022 14.9 1.0 0.022 14.9 1.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 OAP55027.1 - 0.27 11.9 0.0 0.27 11.9 0.0 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.6 OAP55027.1 - 0.3 11.4 1.0 41 4.7 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 OAP55027.1 - 0.44 10.9 10.3 1.6 9.1 0.3 5.2 5 1 0 5 5 5 0 Tetratricopeptide repeat Auxin_repressed PF05564.12 OAP55027.1 - 0.52 11.0 0.1 0.52 11.0 0.1 3.7 3 0 0 3 3 3 0 Dormancy/auxin associated protein PLDc_2 PF13091.6 OAP55028.1 - 7.1e-18 64.8 0.1 8.2e-07 29.0 0.0 3.7 3 1 0 3 3 3 3 PLD-like domain PLDc PF00614.22 OAP55028.1 - 4.8e-14 51.9 3.4 7.8e-08 32.2 0.3 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif NAD_binding_7 PF13241.6 OAP55029.1 - 1.5e-28 99.2 0.0 2.5e-28 98.5 0.0 1.3 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 OAP55029.1 - 7.6e-25 86.3 0.1 1.2e-24 85.8 0.1 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 OAP55029.1 - 2.3e-14 52.5 0.3 3.9e-14 51.8 0.3 1.4 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Pyr_redox_3 PF13738.6 OAP55029.1 - 0.00034 20.0 0.4 0.00057 19.2 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 OAP55029.1 - 0.023 14.8 0.1 0.06 13.4 0.0 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Pribosyltran_N PF13793.6 OAP55030.1 - 1.4e-41 141.1 0.1 5.2e-41 139.2 0.0 2.0 3 0 0 3 3 3 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 OAP55030.1 - 3.1e-30 105.6 0.0 3e-25 89.3 0.0 2.3 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 OAP55030.1 - 1.6e-05 24.5 0.0 0.0027 17.2 0.0 2.5 2 0 0 2 2 2 2 Phosphoribosyl transferase domain Serinc PF03348.15 OAP55031.1 - 7.9e-155 516.0 10.5 8.9e-155 515.8 10.5 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) MFS_1 PF07690.16 OAP55032.1 - 5e-18 65.1 31.7 1.8e-13 50.1 15.6 2.5 1 1 1 3 3 3 2 Major Facilitator Superfamily Nodulin-like PF06813.13 OAP55032.1 - 9.5e-11 41.7 2.4 9.5e-11 41.7 2.4 1.7 2 0 0 2 2 2 1 Nodulin-like Tmemb_170 PF10190.9 OAP55032.1 - 7.4 7.0 8.9 1.1 9.7 2.8 2.9 4 1 0 4 4 4 0 Putative transmembrane protein 170 Shugoshin_N PF07558.11 OAP55033.1 - 0.0002 21.2 1.1 0.00067 19.5 1.1 1.8 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region DUF2046 PF09755.9 OAP55033.1 - 0.0083 15.4 0.6 0.33 10.1 0.1 2.8 3 0 0 3 3 3 1 Uncharacterized conserved protein H4 (DUF2046) Atg14 PF10186.9 OAP55033.1 - 0.018 14.2 4.0 0.026 13.6 0.5 2.2 2 1 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 SlyX PF04102.12 OAP55033.1 - 0.023 15.3 4.5 3.7 8.2 0.1 2.5 2 0 0 2 2 2 0 SlyX bZIP_1 PF00170.21 OAP55033.1 - 0.024 14.7 0.2 0.068 13.3 0.2 1.7 1 0 0 1 1 1 0 bZIP transcription factor TMCO5 PF14992.6 OAP55033.1 - 0.047 13.3 0.9 0.074 12.6 0.9 1.5 1 1 0 1 1 1 0 TMCO5 family DivIC PF04977.15 OAP55033.1 - 0.053 13.3 0.1 0.053 13.3 0.1 2.3 2 0 0 2 2 2 0 Septum formation initiator Jnk-SapK_ap_N PF09744.9 OAP55033.1 - 0.22 11.8 4.1 0.35 11.1 0.1 2.1 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 MerR-DNA-bind PF09278.11 OAP55033.1 - 0.45 11.1 7.1 0.51 10.9 0.3 2.3 2 0 0 2 2 2 0 MerR, DNA binding DUF2968 PF11180.8 OAP55033.1 - 2.7 7.6 10.0 0.61 9.7 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) CEND1 PF15677.5 OAP55034.1 - 0.012 16.2 3.8 0.02 15.4 3.8 1.3 1 0 0 1 1 1 0 Cell cycle exit and neuronal differentiation protein 1 DUF3637 PF12337.8 OAP55034.1 - 0.077 13.3 0.1 0.42 11.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3637) Ank_5 PF13857.6 OAP55035.1 - 0.011 16.0 0.0 0.099 13.0 0.0 2.5 1 1 0 1 1 1 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 OAP55035.1 - 0.013 16.0 0.0 0.22 12.2 0.0 2.1 1 1 1 2 2 2 0 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAP55035.1 - 0.03 14.9 0.0 0.1 13.2 0.0 2.0 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Leu_Phe_trans PF03588.14 OAP55035.1 - 0.045 13.3 0.1 0.11 12.0 0.1 1.6 1 0 0 1 1 1 0 Leucyl/phenylalanyl-tRNA protein transferase Methyltransf_10 PF05971.12 OAP55036.1 - 9.7e-58 195.9 0.0 1.3e-57 195.4 0.0 1.1 1 0 0 1 1 1 1 RNA methyltransferase MTS PF05175.14 OAP55036.1 - 7.8e-05 22.3 0.0 0.00017 21.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain Trypan_PARP PF05887.11 OAP55036.1 - 0.18 11.8 1.5 0.31 11.0 1.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Methyltransf_4 PF02390.17 OAP55036.1 - 0.22 11.0 0.0 0.39 10.2 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Sec7 PF01369.20 OAP55037.1 - 4.4e-72 241.6 0.6 1.8e-71 239.6 0.6 2.2 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 OAP55037.1 - 1.8e-42 144.9 4.3 1.8e-42 144.9 4.3 3.0 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 OAP55037.1 - 5.4e-33 112.7 0.1 5.4e-33 112.7 0.1 5.8 7 0 0 7 7 7 1 Domain of unknown function (DUF1981) DCB PF16213.5 OAP55037.1 - 8.1e-17 61.4 5.8 1.8e-16 60.3 0.9 3.1 3 0 0 3 3 3 1 Dimerisation and cyclophilin-binding domain of Mon2 2-oxoacid_dh PF00198.23 OAP55038.1 - 1.1e-74 250.8 0.1 1.4e-74 250.5 0.1 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 OAP55038.1 - 1.3e-14 53.8 1.0 3.6e-14 52.3 1.0 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 OAP55038.1 - 1.4e-13 51.0 0.8 2.9e-13 49.9 0.8 1.6 1 0 0 1 1 1 1 e3 binding domain Mito_carr PF00153.27 OAP55039.1 - 1.1e-61 204.8 1.8 4.1e-20 71.5 0.7 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein Septin PF00735.18 OAP55040.1 - 4.9e-121 403.3 0.1 4.9e-121 403.3 0.1 1.9 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 OAP55040.1 - 2.6e-08 33.9 0.7 6.1e-08 32.7 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OAP55040.1 - 1.6e-05 24.5 2.3 0.0015 18.1 0.0 3.0 2 2 0 2 2 2 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 OAP55040.1 - 0.00025 21.6 4.3 0.027 15.0 0.0 2.7 2 1 0 2 2 2 1 ABC transporter AAA_16 PF13191.6 OAP55040.1 - 0.0016 18.8 0.2 0.006 17.0 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain Roc PF08477.13 OAP55040.1 - 0.003 17.8 0.0 0.0069 16.6 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 OAP55040.1 - 0.0031 17.4 0.8 0.0031 17.4 0.8 3.6 3 1 0 3 3 3 1 RsgA GTPase AIG1 PF04548.16 OAP55040.1 - 0.0032 16.8 1.9 0.0049 16.2 0.0 2.2 2 0 0 2 2 2 1 AIG1 family AAA_22 PF13401.6 OAP55040.1 - 0.0098 16.2 1.7 0.026 14.8 0.0 2.5 2 2 0 2 2 2 1 AAA domain Ras PF00071.22 OAP55040.1 - 0.01 15.4 0.0 0.053 13.1 0.0 2.2 1 1 0 1 1 1 0 Ras family AAA_29 PF13555.6 OAP55040.1 - 0.02 14.6 0.0 0.037 13.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATP_bind_1 PF03029.17 OAP55040.1 - 0.063 13.0 3.6 1.3 8.7 0.1 3.1 3 1 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_24 PF13479.6 OAP55040.1 - 0.064 13.0 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 OAP55040.1 - 0.071 13.2 8.7 1 9.4 0.0 3.6 3 1 0 3 3 3 0 Dynamin family RNA_helicase PF00910.22 OAP55040.1 - 0.088 13.2 0.6 0.89 10.0 0.0 2.5 2 0 0 2 2 2 0 RNA helicase Caldesmon PF02029.15 OAP55040.1 - 0.23 10.2 16.6 0.48 9.1 16.6 1.5 1 0 0 1 1 1 0 Caldesmon DUF2937 PF11157.8 OAP55040.1 - 0.39 10.4 4.5 1 9.1 4.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) Exonuc_VII_L PF02601.15 OAP55040.1 - 0.7 9.4 8.9 1.3 8.5 8.9 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF87 PF01935.17 OAP55040.1 - 1.2 9.2 3.9 5.4 7.0 0.0 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_32 PF13654.6 OAP55040.1 - 4.7 5.9 18.0 2.1 7.0 0.0 2.6 3 0 0 3 3 3 0 AAA domain Atg14 PF10186.9 OAP55040.1 - 7.8 5.5 9.0 12 4.8 9.0 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 UPF0121 PF03661.13 OAP55041.1 - 4.4e-32 111.4 8.2 6e-32 111.0 8.2 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) ADH_N PF08240.12 OAP55042.1 - 6.1e-21 74.3 0.2 1.2e-20 73.4 0.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAP55042.1 - 8.2e-17 61.4 0.4 1.5e-16 60.6 0.4 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAP55042.1 - 0.0015 19.5 0.0 0.0025 18.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase MOZ_SAS PF01853.18 OAP55043.1 - 2.6e-70 235.7 0.0 4.1e-70 235.1 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 OAP55043.1 - 2e-16 59.3 3.8 3.6e-16 58.5 3.8 1.4 1 0 0 1 1 1 1 MYST family zinc finger domain PHD_4 PF16866.5 OAP55043.1 - 7.4e-06 26.0 6.7 3.1e-05 24.0 6.7 2.2 1 0 0 1 1 1 1 PHD-finger PHD PF00628.29 OAP55043.1 - 3e-05 23.8 6.4 3e-05 23.8 6.4 2.0 2 0 0 2 2 2 1 PHD-finger C1_1 PF00130.22 OAP55043.1 - 0.0034 17.3 1.2 0.0091 15.9 1.2 1.7 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.6 OAP55043.1 - 0.0036 17.2 2.2 0.01 15.7 2.2 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 Anti-TRAP PF15777.5 OAP55043.1 - 0.021 14.8 8.6 0.18 11.8 2.2 2.7 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein zf-RING_9 PF13901.6 OAP55043.1 - 0.18 11.8 4.2 0.33 10.9 4.2 1.4 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon zf-HC5HC2H_2 PF13832.6 OAP55043.1 - 0.3 11.2 2.6 0.58 10.3 2.6 1.4 1 0 0 1 1 1 0 PHD-zinc-finger like domain C1_2 PF03107.16 OAP55043.1 - 3.6 8.0 6.3 1.1 9.7 2.6 2.0 2 0 0 2 2 2 0 C1 domain MWFE PF15879.5 OAP55044.1 - 4.6e-27 94.0 0.2 5.7e-27 93.7 0.2 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase MWFE subunit RraA-like PF03737.15 OAP55045.1 - 7.4e-27 94.4 0.2 1.2e-26 93.7 0.2 1.4 1 0 0 1 1 1 1 Aldolase/RraA Pro_CA PF00484.19 OAP55047.1 - 1.1e-44 152.5 0.0 1.4e-44 152.2 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase FAD_binding_3 PF01494.19 OAP55048.1 - 3.5e-18 66.0 3.0 1.8e-15 57.0 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.7 OAP55048.1 - 3.1e-08 33.4 0.3 5.3e-08 32.6 0.3 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 OAP55048.1 - 4.5e-08 33.1 7.9 0.00093 18.9 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAP55048.1 - 1.7e-06 27.5 2.5 0.0015 17.9 0.9 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAP55048.1 - 1.1e-05 25.9 2.0 0.025 15.1 0.5 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAP55048.1 - 1.3e-05 25.3 1.7 3.1e-05 24.1 1.7 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 OAP55048.1 - 0.00016 20.7 2.7 0.038 12.9 0.8 2.8 3 0 0 3 3 3 2 Tryptophan halogenase GIDA PF01134.22 OAP55048.1 - 0.00044 19.5 1.8 0.00063 18.9 1.8 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 OAP55048.1 - 0.00057 19.1 8.8 0.00086 18.5 6.8 2.1 2 0 0 2 2 2 1 FAD binding domain Amino_oxidase PF01593.24 OAP55048.1 - 0.0012 18.3 2.9 0.34 10.1 0.0 2.5 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase HI0933_like PF03486.14 OAP55048.1 - 0.0064 15.2 5.5 0.014 14.1 4.1 1.9 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 OAP55048.1 - 0.016 14.5 0.6 0.032 13.5 0.6 1.4 1 0 0 1 1 1 0 Thi4 family DUF3603 PF12227.8 OAP55048.1 - 0.039 13.3 0.0 0.065 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3603) Pyr_redox_3 PF13738.6 OAP55048.1 - 0.069 12.4 0.3 0.98 8.6 0.4 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 OAP55048.1 - 0.087 12.7 1.5 0.15 11.9 1.5 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 OAP55048.1 - 0.23 10.7 4.1 0.21 10.8 2.3 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Fungal_trans PF04082.18 OAP55050.1 - 5.4e-35 120.7 0.1 7.7e-35 120.2 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP55050.1 - 4.1e-08 33.2 5.6 8.8e-08 32.2 5.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_25 PF13649.6 OAP55051.1 - 7.4e-18 65.0 0.0 1.2e-17 64.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAP55051.1 - 4.5e-16 59.0 0.0 5.7e-16 58.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAP55051.1 - 7.8e-14 52.1 0.0 1.2e-13 51.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAP55051.1 - 6.9e-13 48.8 0.0 8.2e-13 48.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAP55051.1 - 8.9e-11 42.4 0.0 1.8e-10 41.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 OAP55051.1 - 8.5e-07 29.3 0.0 2e-06 28.0 0.0 1.6 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_2 PF00891.18 OAP55051.1 - 2.5e-05 23.7 0.0 3.6e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_32 PF13679.6 OAP55051.1 - 6e-05 23.1 0.0 8.4e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OAP55051.1 - 7.1e-05 22.4 0.0 0.00011 21.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 OAP55051.1 - 0.00024 20.9 0.0 0.0005 19.9 0.0 1.6 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TehB PF03848.14 OAP55051.1 - 0.0012 18.3 0.0 0.002 17.5 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB RrnaAD PF00398.20 OAP55051.1 - 0.0013 17.9 0.0 0.0018 17.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_4 PF02390.17 OAP55051.1 - 0.0044 16.5 0.0 0.011 15.3 0.0 1.6 2 0 0 2 2 2 1 Putative methyltransferase Ubie_methyltran PF01209.18 OAP55051.1 - 0.016 14.6 0.0 0.025 13.9 0.0 1.4 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_5 PF01795.19 OAP55051.1 - 0.021 14.4 0.0 0.071 12.6 0.0 1.8 2 1 1 3 3 3 0 MraW methylase family TrkA_N PF02254.18 OAP55051.1 - 0.031 14.5 0.0 0.048 13.9 0.0 1.2 1 0 0 1 1 1 0 TrkA-N domain TPMT PF05724.11 OAP55051.1 - 0.097 12.3 0.0 0.17 11.5 0.0 1.5 1 1 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_33 PF10017.9 OAP55051.1 - 0.099 11.8 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent CMAS PF02353.20 OAP55051.1 - 0.14 11.4 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase PhoU PF01895.19 OAP55055.1 - 4.1 7.9 7.1 1.2 9.7 0.7 2.9 2 1 0 2 2 2 0 PhoU domain RRS1 PF04939.12 OAP55056.1 - 8.3e-52 175.3 0.2 1e-51 175.0 0.2 1.1 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) RhoGAP PF00620.27 OAP55057.1 - 2e-29 102.3 0.0 3.4e-29 101.6 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain Prenyltrans PF00432.21 OAP55058.1 - 2.1e-55 184.1 7.6 2.6e-12 46.2 0.0 6.4 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 OAP55058.1 - 5.1e-05 22.5 0.0 0.26 10.4 0.0 3.3 2 1 1 3 3 3 2 Squalene-hopene cyclase N-terminal domain TFIIA PF03153.13 OAP55058.1 - 0.5 10.3 7.1 0.96 9.4 7.1 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CTP_transf_like PF01467.26 OAP55059.1 - 0.0038 17.4 0.5 0.27 11.4 0.3 2.4 2 0 0 2 2 2 2 Cytidylyltransferase-like WD40 PF00400.32 OAP55060.1 - 1.9e-13 50.7 6.9 1.6e-05 25.6 0.2 5.1 4 0 0 4 4 4 3 WD domain, G-beta repeat DUF4831 PF16115.5 OAP55060.1 - 0.21 10.6 0.0 0.21 10.6 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4831) Suf PF05843.14 OAP55060.1 - 1.5 8.7 9.8 3.2 7.6 9.8 1.5 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) E1-E2_ATPase PF00122.20 OAP55061.1 - 3.1e-53 180.0 5.0 6.7e-52 175.6 1.6 2.8 2 0 0 2 2 2 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 OAP55061.1 - 3.6e-44 150.7 5.8 3.6e-44 150.7 5.8 2.2 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 OAP55061.1 - 2.4e-23 83.5 4.0 3.8e-23 82.9 1.5 2.6 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 OAP55061.1 - 1.5e-19 69.5 0.1 4.9e-19 67.8 0.0 2.0 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 OAP55061.1 - 9.4e-18 64.1 0.2 2.4e-17 62.8 0.0 1.8 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 OAP55061.1 - 5.1e-09 36.2 1.8 2.3e-06 27.5 1.1 3.3 4 0 0 4 4 4 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 OAP55061.1 - 3.2e-06 27.7 0.0 1.8e-05 25.2 0.0 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase 14-3-3 PF00244.20 OAP55062.1 - 5.1e-108 359.7 2.7 5.8e-108 359.5 2.7 1.0 1 0 0 1 1 1 1 14-3-3 protein Ima1_N PF09779.9 OAP55062.1 - 0.12 13.2 0.7 6.1 7.7 0.4 2.9 2 1 0 2 2 2 0 Ima1 N-terminal domain MFS_1 PF07690.16 OAP55064.1 - 1.9e-28 99.4 27.8 1.9e-28 99.4 27.8 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAP55064.1 - 4.2e-07 29.2 12.9 4.2e-07 29.2 12.9 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter HET PF06985.11 OAP55065.1 - 7e-24 84.8 0.0 1.3e-23 84.0 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) CFEM PF05730.11 OAP55066.1 - 0.0012 18.8 15.7 0.0019 18.2 10.3 3.1 2 1 0 2 2 2 1 CFEM domain Ilm1 PF10311.9 OAP55067.1 - 1.1e-19 70.7 0.6 1.9e-11 43.9 0.1 2.4 2 1 0 2 2 2 2 Increased loss of mitochondrial DNA protein 1 adh_short PF00106.25 OAP55068.1 - 2.1e-32 112.2 0.0 3e-32 111.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP55068.1 - 6.3e-25 88.1 0.2 8.3e-25 87.7 0.2 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP55068.1 - 0.0007 19.5 0.0 0.0066 16.4 0.0 2.1 2 0 0 2 2 2 1 KR domain Upf2 PF04050.14 OAP55069.1 - 0.044 14.5 0.7 0.44 11.3 0.3 2.5 2 0 0 2 2 2 0 Up-frameshift suppressor 2 EzrA PF06160.12 OAP55071.1 - 0.39 8.8 5.7 0.041 12.1 1.5 1.4 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA Lzipper-MIP1 PF14389.6 OAP55071.1 - 0.46 10.8 6.2 0.44 10.9 3.0 2.8 2 1 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Jnk-SapK_ap_N PF09744.9 OAP55071.1 - 2 8.6 12.2 0.34 11.1 2.7 2.6 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 SKA2 PF16740.5 OAP55071.1 - 4.1 7.2 7.5 0.29 10.9 1.2 2.4 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 2 CENP-H PF05837.12 OAP55071.1 - 4.4 7.7 11.3 3.5 8.1 0.3 3.4 4 0 0 4 4 4 0 Centromere protein H (CENP-H) Filament PF00038.21 OAP55071.1 - 4.7 6.7 16.3 0.089 12.4 5.0 2.7 1 1 0 2 2 2 0 Intermediate filament protein DUF1640 PF07798.11 OAP55072.1 - 9.3e-57 191.9 8.8 1.1e-56 191.6 8.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) MerR_1 PF13411.6 OAP55072.1 - 0.061 13.4 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 MerR HTH family regulatory protein XhlA PF10779.9 OAP55072.1 - 0.2 11.9 0.2 0.2 11.9 0.2 2.0 3 0 0 3 3 3 0 Haemolysin XhlA GreA_GreB_N PF03449.15 OAP55072.1 - 0.9 9.7 6.6 2.5 8.3 5.9 2.2 2 0 0 2 2 2 0 Transcription elongation factor, N-terminal TPR_MLP1_2 PF07926.12 OAP55072.1 - 4.2 7.4 13.6 12 5.9 12.7 2.0 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Peptidase_M48_N PF16491.5 OAP55073.1 - 8.2e-66 221.4 9.3 8.2e-66 221.4 9.3 1.9 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 OAP55073.1 - 5.2e-47 160.2 0.1 1e-46 159.2 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.11 OAP55073.1 - 0.00097 18.4 0.5 0.0024 17.1 0.1 1.8 2 0 0 2 2 2 1 BlaR1 peptidase M56 DUF4538 PF15061.6 OAP55073.1 - 0.0069 16.1 0.7 0.02 14.6 0.7 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4538) B PF02216.16 OAP55074.1 - 0.014 15.3 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 B domain BATS PF06968.13 OAP55075.1 - 3.9e-23 81.4 0.0 1e-22 80.1 0.0 1.7 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 OAP55075.1 - 1.3e-14 54.9 0.1 2.6e-14 53.9 0.1 1.5 1 0 0 1 1 1 1 Radical SAM superfamily SHR3_chaperone PF08229.11 OAP55078.1 - 1.1e-77 259.2 0.0 1.3e-77 259.0 0.0 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 MFS_1 PF07690.16 OAP55078.1 - 0.043 12.7 3.8 0.23 10.3 5.0 1.5 2 0 0 2 2 2 0 Major Facilitator Superfamily RNA_polI_A14 PF08203.11 OAP55079.1 - 0.018 15.7 0.8 0.1 13.3 0.0 2.6 2 1 0 2 2 2 0 Yeast RNA polymerase I subunit RPA14 DUF1330 PF07045.11 OAP55080.1 - 0.17 12.2 0.0 0.26 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1330) Sigma70_r4_2 PF08281.12 OAP55081.1 - 0.04 13.6 0.0 0.074 12.7 0.0 1.3 1 0 0 1 1 1 0 Sigma-70, region 4 MSA-2c PF12238.8 OAP55081.1 - 6.2 6.8 7.4 10 6.0 7.4 1.3 1 0 0 1 1 1 0 Merozoite surface antigen 2c Aldose_epim PF01263.20 OAP55082.1 - 1.8e-42 145.7 0.0 2.1e-42 145.5 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase DUF4432 PF14486.6 OAP55082.1 - 0.041 12.7 0.0 0.056 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4432) AT_hook PF02178.19 OAP55083.1 - 0.00041 19.9 8.7 0.018 14.9 1.5 3.2 2 0 0 2 2 2 2 AT hook motif Acetyltransf_3 PF13302.7 OAP55085.1 - 2.6e-14 54.1 0.0 3.4e-14 53.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAP55085.1 - 5.8e-06 26.5 0.0 8.5e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 OAP55085.1 - 0.00044 20.4 0.0 0.00056 20.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain MFS_1 PF07690.16 OAP55086.1 - 4.4e-43 147.5 45.8 6.9e-42 143.6 43.8 2.6 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 OAP55086.1 - 4.9e-14 51.7 23.6 7.2e-14 51.1 23.6 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 OAP55086.1 - 1.2e-09 37.6 12.1 1.2e-09 37.6 12.1 3.8 3 1 1 4 4 4 3 Sugar (and other) transporter Prefoldin_3 PF13758.6 OAP55087.1 - 3.1e-24 84.9 0.6 8.5e-24 83.5 0.6 1.8 1 0 0 1 1 1 1 Prefoldin subunit DUF3835 PF12927.7 OAP55087.1 - 1e-16 61.5 11.9 3.3e-15 56.7 0.1 4.2 4 0 0 4 4 4 2 Domain of unknown function (DUF3835) DUF3213 PF11491.8 OAP55087.1 - 0.31 11.2 1.6 0.61 10.3 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3213) HR1 PF02185.16 OAP55087.1 - 1.8 8.7 8.4 0.36 11.0 0.4 3.1 3 0 0 3 3 3 0 Hr1 repeat MAT1 PF06391.13 OAP55088.1 - 2e-23 83.3 5.8 2.6e-23 82.9 5.8 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_5 PF17121.5 OAP55088.1 - 5.6e-16 58.2 6.8 8.5e-16 57.6 6.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAP55088.1 - 4.2e-05 23.3 3.2 8.8e-05 22.3 3.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OAP55088.1 - 0.00049 19.9 5.8 0.00062 19.5 0.4 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OAP55088.1 - 0.0073 16.1 6.4 0.016 15.0 6.4 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAP55088.1 - 0.0073 16.2 8.6 0.05 13.6 8.7 2.1 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 OAP55088.1 - 0.018 15.4 6.2 0.031 14.6 6.2 1.4 1 0 0 1 1 1 0 Ring finger domain zf-RING_UBOX PF13445.6 OAP55088.1 - 0.046 13.8 6.1 0.09 12.8 6.1 1.5 1 0 0 1 1 1 0 RING-type zinc-finger Zn_ribbon_17 PF17120.5 OAP55088.1 - 0.28 10.9 7.6 0.56 9.9 7.6 1.5 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 OAP55088.1 - 0.35 10.8 7.3 0.28 11.1 1.7 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 PCI PF01399.27 OAP55089.1 - 8.1e-12 45.6 0.1 3.3e-11 43.6 0.0 2.0 2 0 0 2 2 2 1 PCI domain eIF3m_C_helix PF18005.1 OAP55089.1 - 1.3e-10 40.7 2.7 2.7e-10 39.8 2.7 1.6 1 0 0 1 1 1 1 eIF3 subunit M, C-terminal helix FANCI_S3 PF14677.6 OAP55089.1 - 0.019 14.7 0.1 0.084 12.6 0.0 1.8 1 1 1 2 2 2 0 FANCI solenoid 3 Myb_DNA-bind_6 PF13921.6 OAP55090.1 - 1.6e-16 60.2 2.4 3e-16 59.4 0.0 2.6 3 0 0 3 3 3 1 Myb-like DNA-binding domain HSA PF07529.13 OAP55090.1 - 1.7e-12 47.4 0.1 1.7e-12 47.4 0.1 4.0 5 0 0 5 5 5 1 HSA Myb_DNA-binding PF00249.31 OAP55090.1 - 6.3e-05 23.1 0.1 0.00017 21.7 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Prok-JAB PF14464.6 OAP55090.1 - 0.061 13.1 0.6 0.34 10.7 0.3 2.5 2 0 0 2 2 2 0 Prokaryotic homologs of the JAB domain WD40 PF00400.32 OAP55091.1 - 2.8e-09 37.4 0.1 0.06 14.3 0.0 6.0 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAP55091.1 - 0.0002 21.6 0.0 5.4 7.4 0.0 4.7 4 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain ADK PF00406.22 OAP55092.1 - 1e-44 152.3 0.0 1.3e-44 152.0 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 OAP55092.1 - 1.6e-35 122.5 0.0 2e-35 122.1 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 OAP55092.1 - 2.9e-10 40.8 0.0 3.8e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 OAP55092.1 - 3.8e-07 30.4 0.1 6.3e-06 26.4 0.1 2.1 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 OAP55092.1 - 0.0024 17.6 0.1 1.8 8.2 0.0 2.2 2 0 0 2 2 2 2 Thymidylate kinase Ploopntkinase3 PF18751.1 OAP55092.1 - 0.099 12.6 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 Clathrin PF00637.20 OAP55093.1 - 4.7e-202 662.0 37.7 4.3e-33 114.2 0.6 8.2 8 0 0 8 8 8 7 Region in Clathrin and VPS Clathrin_H_link PF13838.6 OAP55093.1 - 3.2e-33 113.4 3.5 1.2e-32 111.6 0.7 3.5 3 1 1 4 4 4 1 Clathrin-H-link Clathrin_propel PF01394.20 OAP55093.1 - 3.1e-30 103.0 2.1 1.5e-06 28.2 0.0 6.4 6 0 0 6 6 6 5 Clathrin propeller repeat Clathrin-link PF09268.10 OAP55093.1 - 4.1e-05 22.9 2.0 0.00095 18.5 0.5 2.6 2 0 0 2 2 2 1 Clathrin, heavy-chain linker TPR_7 PF13176.6 OAP55093.1 - 9.8e-05 22.1 9.4 7.6 6.8 0.0 7.4 7 0 0 7 7 7 1 Tetratricopeptide repeat Vps39_1 PF10366.9 OAP55093.1 - 0.00016 21.9 5.2 1.1 9.6 0.0 5.6 4 0 0 4 4 4 1 Vacuolar sorting protein 39 domain 1 TPR_1 PF00515.28 OAP55093.1 - 0.00027 20.6 3.3 4.7 7.2 0.0 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 OAP55093.1 - 0.00047 20.8 14.2 9.7 7.3 0.0 9.8 11 0 0 11 11 10 1 Tetratricopeptide repeat TPR_8 PF13181.6 OAP55093.1 - 0.0042 17.2 2.6 3.4 8.1 0.0 5.6 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 OAP55093.1 - 0.0054 17.0 9.9 5.4 7.4 0.0 6.7 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_2 PF07719.17 OAP55093.1 - 0.0076 16.3 11.5 7.2 7.0 0.0 7.4 8 0 0 8 8 7 1 Tetratricopeptide repeat Coatomer_WDAD PF04053.14 OAP55093.1 - 0.0087 15.1 10.6 0.47 9.4 0.2 4.1 4 0 0 4 4 4 2 Coatomer WD associated region 6PF2K PF01591.18 OAP55093.1 - 0.019 14.3 1.1 0.14 11.5 0.2 2.4 2 0 0 2 2 2 0 6-phosphofructo-2-kinase DUF1720 PF08226.11 OAP55093.1 - 0.024 15.0 4.5 0.022 15.1 1.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1720) DUF1400 PF07176.11 OAP55093.1 - 0.38 11.0 3.0 19 5.5 0.1 4.1 4 0 0 4 4 4 0 Alpha/beta hydrolase of unknown function (DUF1400) TPR_10 PF13374.6 OAP55093.1 - 7.8 6.5 11.5 69 3.5 0.0 6.5 8 0 0 8 8 8 0 Tetratricopeptide repeat CPSase_L_D2 PF02786.17 OAP55094.1 - 5.2e-82 274.4 0.1 8.1e-82 273.8 0.1 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 OAP55094.1 - 7.1e-71 238.1 0.1 1.4e-70 237.1 0.1 1.5 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_carb_N PF00289.22 OAP55094.1 - 1.4e-38 131.8 0.1 2.7e-38 130.9 0.1 1.5 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 OAP55094.1 - 1.2e-30 105.7 0.0 3.2e-30 104.4 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 OAP55094.1 - 1.9e-26 93.2 0.0 3.5e-26 92.3 0.0 1.4 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 OAP55094.1 - 3.2e-18 65.3 6.3 3.2e-18 65.3 3.8 2.3 2 0 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 OAP55094.1 - 4e-10 39.6 0.0 8.1e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.6 OAP55094.1 - 1.8e-09 37.3 2.4 8.2e-05 22.4 0.1 3.3 2 1 1 3 3 3 2 Biotin-lipoyl like ATP-grasp PF02222.22 OAP55094.1 - 1.5e-07 31.2 0.0 3.3e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 OAP55094.1 - 2.9e-05 24.2 0.0 5.6e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 OAP55094.1 - 3.6e-05 23.4 0.0 9.1e-05 22.1 0.0 1.6 1 1 0 1 1 1 1 RimK-like ATP-grasp domain HlyD_3 PF13437.6 OAP55094.1 - 0.0018 19.0 0.3 0.95 10.2 0.0 3.0 3 0 0 3 3 3 1 HlyD family secretion protein HlyD_D23 PF16576.5 OAP55094.1 - 0.0025 17.0 0.1 0.17 11.1 0.0 2.3 1 1 1 2 2 2 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion ATP-grasp_4 PF13535.6 OAP55094.1 - 0.014 15.0 0.1 0.041 13.5 0.0 1.9 2 0 0 2 2 2 0 ATP-grasp domain GARS_A PF01071.19 OAP55094.1 - 0.03 14.1 0.0 0.069 12.9 0.0 1.6 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain DUF2118 PF09891.9 OAP55094.1 - 0.037 14.0 0.1 0.12 12.4 0.1 1.9 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) GCV_H PF01597.19 OAP55094.1 - 0.082 12.8 1.2 0.5 10.3 0.4 2.7 2 1 1 3 3 2 0 Glycine cleavage H-protein RnfC_N PF13375.6 OAP55094.1 - 0.16 11.9 1.2 1.4 9.0 1.3 2.2 1 1 1 2 2 2 0 RnfC Barrel sandwich hybrid domain ASFV_J13L PF05568.11 OAP55095.1 - 0.11 12.2 1.6 0.13 12.0 1.6 1.1 1 0 0 1 1 1 0 African swine fever virus J13L protein Hamartin PF04388.12 OAP55095.1 - 0.17 10.5 1.4 0.19 10.3 1.4 1.0 1 0 0 1 1 1 0 Hamartin protein MPC PF03650.13 OAP55096.1 - 7e-35 119.5 0.1 9.6e-35 119.1 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers Rif1_N PF12231.8 OAP55097.1 - 3.9e-113 378.3 1.6 3.9e-113 378.3 0.4 1.6 2 0 0 2 2 2 1 Rap1-interacting factor 1 N terminal Ric8 PF10165.9 OAP55098.1 - 4.4e-112 375.5 3.3 5.1e-112 375.3 3.3 1.0 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn GHMP_kinases_N PF00288.26 OAP55099.1 - 2.5e-16 59.7 0.3 7.3e-16 58.2 0.0 2.0 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 OAP55099.1 - 8.4e-07 29.3 0.0 1.8e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.9 OAP55099.1 - 0.0089 15.6 0.1 0.017 14.7 0.1 1.4 1 0 0 1 1 1 1 Galactokinase galactose-binding signature PPTA PF01239.22 OAP55100.1 - 4.3e-37 124.8 15.5 1.4e-07 31.0 1.1 5.3 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat p450 PF00067.22 OAP55101.1 - 6.6e-56 190.0 0.0 9.6e-56 189.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 AICARFT_IMPCHas PF01808.18 OAP55102.1 - 5.3e-91 305.1 0.0 7.9e-91 304.6 0.0 1.3 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 OAP55102.1 - 2.6e-23 82.0 0.0 4.7e-23 81.2 0.0 1.4 1 0 0 1 1 1 1 MGS-like domain Dis3l2_C_term PF17877.1 OAP55102.1 - 0.064 13.6 0.0 0.14 12.5 0.0 1.5 1 0 0 1 1 1 0 DIS3-like exonuclease 2 C terminal US30 PF17624.2 OAP55103.1 - 0.14 11.2 0.3 0.29 10.1 0.3 1.5 1 0 0 1 1 1 0 Family of unknown function FixQ PF05545.11 OAP55104.1 - 0.04 13.9 0.9 0.12 12.4 0.2 2.1 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ TMEM192 PF14802.6 OAP55104.1 - 0.23 10.5 1.2 6.7 5.7 0.4 2.1 2 0 0 2 2 2 0 TMEM192 family Pam17 PF08566.10 OAP55106.1 - 1.4e-59 200.7 0.0 1.9e-59 200.2 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 Colicin_V PF02674.16 OAP55106.1 - 0.074 13.0 0.1 0.11 12.5 0.1 1.2 1 0 0 1 1 1 0 Colicin V production protein Fungal_trans_2 PF11951.8 OAP55107.1 - 1.3e-60 205.3 0.7 2e-60 204.7 0.7 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP55107.1 - 5.6e-09 36.0 9.3 1e-08 35.2 9.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Far-17a_AIG1 PF04750.14 OAP55108.1 - 8e-57 191.8 12.0 9.1e-57 191.6 12.0 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein ATP1G1_PLM_MAT8 PF02038.16 OAP55108.1 - 0.13 11.7 0.2 0.26 10.7 0.2 1.5 1 0 0 1 1 1 0 ATP1G1/PLM/MAT8 family PALP PF00291.25 OAP55109.1 - 1.9e-43 149.0 0.1 2.3e-43 148.7 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme LYTB PF02401.18 OAP55109.1 - 0.16 11.2 0.0 0.26 10.5 0.0 1.2 1 0 0 1 1 1 0 LytB protein NHL PF01436.21 OAP55110.1 - 0.16 12.1 0.2 3.8 7.7 0.0 2.3 2 0 0 2 2 2 0 NHL repeat DUF4381 PF14316.6 OAP55111.1 - 0.0023 18.2 1.0 0.0051 17.1 1.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4381) LapA_dom PF06305.11 OAP55111.1 - 0.16 11.8 1.9 0.43 10.4 1.9 1.6 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain DUF3021 PF11457.8 OAP55111.1 - 0.22 11.8 1.6 0.37 11.1 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3021) SSP160 PF06933.11 OAP55112.1 - 3.3 5.8 28.4 4.1 5.5 28.4 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 FSA_C PF10479.9 OAP55112.1 - 5.3 5.0 13.8 6.1 4.8 13.8 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus FAD_binding_3 PF01494.19 OAP55113.1 - 1.1e-09 38.0 0.0 0.00011 21.6 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 OAP55113.1 - 8.9e-05 21.7 0.0 0.00015 20.9 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 OAP55113.1 - 0.012 14.9 0.0 0.019 14.2 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 OAP55113.1 - 0.074 11.9 0.0 0.42 9.4 0.0 1.9 2 0 0 2 2 2 0 Tryptophan halogenase SE PF08491.10 OAP55113.1 - 0.14 11.2 0.0 1 8.3 0.0 2.0 2 1 0 2 2 2 0 Squalene epoxidase ADH_zinc_N PF00107.26 OAP55114.1 - 7e-23 81.0 0.1 1.4e-22 80.1 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAP55114.1 - 1e-22 80.1 5.4 1e-22 80.1 5.4 1.6 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 OAP55114.1 - 2.2e-06 28.7 0.0 3.8e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 OAP55114.1 - 2.2e-05 24.1 0.2 3.4e-05 23.4 0.2 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus Peptidase_S28 PF05577.12 OAP55115.1 - 3.5e-40 138.1 0.0 5.6e-40 137.4 0.0 1.3 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_6 PF12697.7 OAP55116.1 - 9.9e-05 23.0 6.2 0.00047 20.8 6.2 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAP55116.1 - 0.18 11.4 0.1 3.2 7.3 0.1 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF3336 PF11815.8 OAP55117.1 - 4.8e-25 87.9 0.0 8.6e-25 87.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 OAP55117.1 - 5.3e-21 75.7 0.0 1.7e-20 74.1 0.0 1.8 2 0 0 2 2 2 1 Patatin-like phospholipase mRNA_triPase PF02940.15 OAP55118.1 - 8.7e-49 166.2 0.0 1.2e-48 165.7 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain RPN2_C PF18004.1 OAP55119.1 - 5e-54 182.5 17.1 5.4e-54 182.4 9.3 2.4 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 OAP55119.1 - 3.7e-32 109.1 14.9 2.6e-09 37.1 0.0 8.7 9 0 0 9 9 9 6 Proteasome/cyclosome repeat HEAT_2 PF13646.6 OAP55119.1 - 7.8e-20 71.1 0.2 4e-14 52.8 0.1 4.3 2 1 2 4 4 4 4 HEAT repeats HEAT PF02985.22 OAP55119.1 - 7.9e-07 28.8 0.0 1.6 9.2 0.0 5.9 5 0 0 5 5 5 1 HEAT repeat HEAT_EZ PF13513.6 OAP55119.1 - 1.1e-06 29.0 1.0 0.00011 22.7 0.1 4.4 3 1 1 4 4 4 2 HEAT-like repeat Cnd1 PF12717.7 OAP55119.1 - 0.16 12.0 0.1 2.9 7.9 0.0 2.7 1 1 1 2 2 2 0 non-SMC mitotic condensation complex subunit 1 HEAT_PBS PF03130.16 OAP55119.1 - 0.24 12.2 3.2 1.7 9.6 0.1 3.7 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat Ribosomal_S8 PF00410.19 OAP55120.1 - 1.1e-12 48.0 0.0 1.1e-11 44.8 0.0 2.2 1 1 0 1 1 1 1 Ribosomal protein S8 Pkinase_Tyr PF07714.17 OAP55121.1 - 0.13 11.5 0.1 0.18 11.1 0.1 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Zn_clus PF00172.18 OAP55122.1 - 6.3e-05 23.0 10.7 0.00012 22.1 10.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cep3 PF16846.5 OAP55122.1 - 0.076 11.5 0.1 0.11 11.0 0.1 1.1 1 0 0 1 1 1 0 Centromere DNA-binding protein complex CBF3 subunit B Amidohydro_1 PF01979.20 OAP55123.1 - 2e-62 211.5 0.0 2.6e-62 211.2 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 OAP55123.1 - 1.6e-25 90.5 0.2 6.1e-20 72.1 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family A_deaminase PF00962.22 OAP55123.1 - 0.00023 20.6 0.1 0.00094 18.6 0.0 1.9 2 0 0 2 2 2 1 Adenosine/AMP deaminase Xan_ur_permease PF00860.20 OAP55124.1 - 2.9e-55 187.6 36.6 1.2e-54 185.6 36.6 1.8 1 1 0 1 1 1 1 Permease family MFS_MOT1 PF16983.5 OAP55124.1 - 0.003 17.9 3.9 0.003 17.9 3.9 3.7 3 1 0 3 3 3 1 Molybdate transporter of MFS superfamily BRI3BP PF14965.6 OAP55124.1 - 0.069 12.7 0.5 0.2 11.1 0.1 2.0 2 0 0 2 2 2 0 Negative regulator of p53/TP53 Acetyltransf_10 PF13673.7 OAP55125.1 - 1.7e-10 40.9 0.0 4.1e-10 39.7 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAP55125.1 - 3.7e-09 36.8 0.0 1.1e-08 35.3 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OAP55125.1 - 2.7e-08 34.1 0.0 8.2e-08 32.6 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 OAP55125.1 - 0.00018 21.6 0.0 0.00032 20.8 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 OAP55125.1 - 0.0067 16.5 0.1 0.052 13.6 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Amidoligase_2 PF12224.8 OAP55126.1 - 7.2e-15 55.3 2.2 1.7e-06 27.9 0.4 2.9 2 1 0 2 2 2 2 Putative amidoligase enzyme Cut12 PF11500.8 OAP55126.1 - 0.081 12.9 0.8 0.2 11.6 0.8 1.6 1 0 0 1 1 1 0 Spindle pole body formation-associated protein MFS_1 PF07690.16 OAP55127.1 - 2.7e-23 82.5 28.8 2.7e-23 82.5 28.8 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily PBP PF01161.20 OAP55129.1 - 1.3e-11 45.0 0.1 1.8e-11 44.5 0.1 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Kei1 PF08552.11 OAP55129.1 - 0.37 10.6 4.7 0.61 9.9 4.7 1.2 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 F-box-like PF12937.7 OAP55130.1 - 0.0025 17.7 0.3 0.024 14.5 0.0 2.4 2 0 0 2 2 2 1 F-box-like DZR PF12773.7 OAP55130.1 - 0.042 13.9 3.6 0.088 12.8 3.6 1.5 1 0 0 1 1 1 0 Double zinc ribbon F-box PF00646.33 OAP55130.1 - 0.23 11.4 0.0 0.23 11.4 0.0 2.3 3 0 0 3 3 3 0 F-box domain ADH_zinc_N PF00107.26 OAP55131.1 - 1.9e-18 66.7 0.0 6.4e-18 65.0 0.1 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAP55131.1 - 9.8e-11 42.8 0.0 2e-10 41.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAP55131.1 - 2.5e-06 27.3 0.0 3.2e-05 23.8 0.0 2.3 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain SnoaL_2 PF12680.7 OAP55131.1 - 4.2e-05 24.1 0.0 0.00014 22.5 0.0 2.0 1 0 0 1 1 1 1 SnoaL-like domain Glyco_hydro_125 PF06824.11 OAP55132.1 - 2.7e-15 56.2 0.0 1e-14 54.3 0.0 1.8 1 1 1 2 2 2 1 Metal-independent alpha-mannosidase (GH125) Fungal_trans PF04082.18 OAP55132.1 - 3.8e-11 42.5 0.0 8.9e-11 41.3 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 OAP55133.1 - 9.9e-31 106.9 23.5 9.9e-31 106.9 23.5 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily RPAP1_N PF08621.10 OAP55133.1 - 0.036 13.8 0.3 0.064 13.0 0.3 1.3 1 0 0 1 1 1 0 RPAP1-like, N-terminal DUF4748 PF15932.5 OAP55133.1 - 0.19 11.5 0.0 0.19 11.5 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4748) Vma12 PF11712.8 OAP55133.1 - 0.28 11.2 0.8 1.6 8.8 0.8 2.2 1 1 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase APG5 PF04106.12 OAP55135.1 - 6.6e-57 192.7 0.0 9.5e-57 192.2 0.0 1.2 1 0 0 1 1 1 1 Autophagy protein Apg5 AbiJ_NTD3 PF18860.1 OAP55138.1 - 0.068 12.7 0.1 0.12 11.9 0.1 1.3 1 0 0 1 1 1 0 AbiJ N-terminal domain 3 Sugar_tr PF00083.24 OAP55139.1 - 8.2e-81 272.1 19.3 9.4e-81 272.0 19.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP55139.1 - 5.8e-22 78.1 25.3 5.8e-22 78.1 25.3 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily FPN1 PF06963.12 OAP55139.1 - 0.026 13.1 2.8 0.057 12.0 2.8 1.5 1 0 0 1 1 1 0 Ferroportin1 (FPN1) Ldr_toxin PF13940.6 OAP55139.1 - 0.61 10.2 3.1 0.64 10.1 0.8 2.3 2 0 0 2 2 2 0 Toxin Ldr, type I toxin-antitoxin system FmiP_Thoc5 PF09766.9 OAP55140.1 - 4.9e-24 85.3 8.7 6.5e-24 84.9 8.7 1.2 1 0 0 1 1 1 1 Fms-interacting protein/Thoc5 DUF2935 PF11155.8 OAP55140.1 - 0.76 10.1 5.5 0.45 10.8 1.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF2935) Methyltransf_25 PF13649.6 OAP55141.1 - 1.9e-15 57.3 0.0 4.5e-15 56.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAP55141.1 - 5.8e-14 52.6 0.0 1.8e-13 51.1 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAP55141.1 - 1.7e-13 50.8 0.0 3e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAP55141.1 - 1.7e-11 44.6 0.0 4.7e-11 43.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAP55141.1 - 9.8e-10 38.4 0.0 1.4e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAP55141.1 - 8.1e-08 31.9 0.0 1.2e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_24 PF13578.6 OAP55141.1 - 0.00023 22.1 0.0 0.00067 20.7 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain MTS PF05175.14 OAP55141.1 - 0.0022 17.6 0.0 0.0037 16.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_8 PF05148.15 OAP55141.1 - 0.0072 16.2 0.0 0.15 11.9 0.0 2.2 1 1 0 1 1 1 1 Hypothetical methyltransferase CMAS PF02353.20 OAP55141.1 - 0.038 13.3 0.0 0.06 12.6 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase TPMT PF05724.11 OAP55141.1 - 0.052 13.2 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) DUF3419 PF11899.8 OAP55141.1 - 0.06 12.5 0.0 0.096 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3419) UPF0020 PF01170.18 OAP55141.1 - 0.074 12.7 0.0 0.16 11.6 0.0 1.5 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 TehB PF03848.14 OAP55141.1 - 0.086 12.2 0.0 0.26 10.7 0.0 1.7 2 0 0 2 2 2 0 Tellurite resistance protein TehB Methyltransf_4 PF02390.17 OAP55141.1 - 0.098 12.1 0.0 0.49 9.9 0.0 2.1 1 1 0 1 1 1 0 Putative methyltransferase GCD14 PF08704.10 OAP55141.1 - 0.12 12.0 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit NNMT_PNMT_TEMT PF01234.17 OAP55141.1 - 0.15 11.2 0.0 2.7 7.1 0.0 2.1 1 1 1 2 2 2 0 NNMT/PNMT/TEMT family Roc PF08477.13 OAP55141.1 - 0.17 12.1 0.4 1.4 9.1 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase HlyIII PF03006.20 OAP55142.1 - 1.2e-60 205.0 22.7 1.5e-60 204.7 22.7 1.1 1 0 0 1 1 1 1 Haemolysin-III related Fungal_trans_2 PF11951.8 OAP55143.1 - 1.1e-05 24.4 3.4 1.4e-05 24.1 3.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Arrestin_N PF00339.29 OAP55146.1 - 2.7e-09 37.2 0.0 1.5e-08 34.8 0.0 2.1 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain DUF4046 PF13255.6 OAP55146.1 - 0.072 13.6 0.0 0.21 12.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4046) Fungal_trans PF04082.18 OAP55148.1 - 1.2e-28 99.9 0.2 2.1e-28 99.1 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP55148.1 - 1.5e-09 37.8 8.0 3e-09 36.9 8.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HD_4 PF13328.6 OAP55149.1 - 0.048 13.4 0.0 0.079 12.7 0.0 1.3 1 0 0 1 1 1 0 HD domain MFS_1 PF07690.16 OAP55151.1 - 1.5e-15 57.0 35.4 2.8e-12 46.2 23.5 2.7 2 1 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 OAP55151.1 - 0.0021 16.4 6.3 0.011 14.1 1.8 3.4 2 1 1 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family DUF3784 PF12650.7 OAP55151.1 - 0.063 13.5 0.1 0.063 13.5 0.1 4.4 5 0 0 5 5 5 0 Domain of unknown function (DUF3784) Herpes_pp38 PF04846.13 OAP55151.1 - 2 8.4 13.5 0.88 9.5 1.9 3.4 3 0 0 3 3 3 0 Herpesvirus pp38 phosphoprotein LRV PF01816.17 OAP55152.1 - 0.024 15.0 5.4 0.048 14.1 5.4 1.5 1 0 0 1 1 1 0 Leucine rich repeat variant DLH PF01738.18 OAP55153.1 - 1.8e-12 47.3 0.0 2.6e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 OAP55153.1 - 0.0039 17.8 4.6 0.026 15.1 4.6 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Fungal_trans_2 PF11951.8 OAP55155.1 - 7.1e-05 21.8 0.1 0.00012 21.1 0.1 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain GDE_N_bis PF14742.6 OAP55155.1 - 0.13 11.8 0.0 0.21 11.1 0.0 1.4 1 1 0 1 1 1 0 N-terminal domain of (some) glycogen debranching enzymes Ferritin_2 PF13668.6 OAP55156.1 - 6.7e-12 45.8 0.0 1.2e-11 45.0 0.0 1.3 1 0 0 1 1 1 1 Ferritin-like domain Peptidase_M20 PF01546.28 OAP55157.1 - 1.3e-08 34.8 0.0 2.3e-08 34.0 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 OAP55157.1 - 6.2e-08 32.5 0.0 4e-07 29.9 0.0 2.3 2 0 0 2 2 2 1 Peptidase dimerisation domain T6SS_VasE PF05936.12 OAP55157.1 - 0.17 10.6 0.0 0.23 10.1 0.0 1.1 1 0 0 1 1 1 0 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE DUF4286 PF14114.6 OAP55158.1 - 8.7e-05 22.9 0.1 0.057 13.9 0.1 2.4 3 0 0 3 3 3 2 Domain of unknown function (DUF4286) DUF1100 PF06500.11 OAP55159.1 - 5.3e-12 45.3 0.0 6.7e-12 44.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Peptidase_S15 PF02129.18 OAP55159.1 - 6e-07 29.3 0.0 1.3e-06 28.2 0.0 1.5 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 OAP55159.1 - 1e-06 28.4 0.0 1.7e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 OAP55159.1 - 1.2e-05 25.1 0.0 0.015 14.9 0.0 2.2 2 0 0 2 2 2 2 Putative esterase Hydrolase_4 PF12146.8 OAP55159.1 - 0.00031 20.1 0.0 0.014 14.7 0.0 2.2 1 1 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OAP55159.1 - 0.00056 19.6 0.0 0.047 13.3 0.0 2.2 1 1 1 2 2 2 1 alpha/beta hydrolase fold BAAT_C PF08840.11 OAP55159.1 - 0.037 13.9 0.0 0.069 13.1 0.0 1.4 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal NUC173 PF08161.12 OAP55159.1 - 0.15 11.7 0.0 0.25 11.0 0.0 1.2 1 0 0 1 1 1 0 NUC173 domain Ank_2 PF12796.7 OAP55160.1 - 3.9e-41 139.5 5.3 2e-09 37.9 0.0 6.2 3 2 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OAP55160.1 - 2.3e-30 104.2 10.9 1.5e-09 38.0 0.8 7.4 4 3 4 8 8 8 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAP55160.1 - 1.1e-29 99.2 6.2 0.0015 18.8 0.1 9.2 9 0 0 9 9 8 6 Ankyrin repeat Ank PF00023.30 OAP55160.1 - 7.1e-29 99.0 9.3 0.00014 22.2 0.1 9.0 8 0 0 8 8 8 6 Ankyrin repeat Ank_4 PF13637.6 OAP55160.1 - 1.4e-27 95.7 7.5 3.6e-07 30.6 0.2 8.9 5 3 5 10 10 10 7 Ankyrin repeats (many copies) NACHT PF05729.12 OAP55160.1 - 4.2e-10 39.8 0.1 9.6e-10 38.6 0.1 1.6 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 OAP55160.1 - 1.2e-06 28.9 0.1 5.5e-06 26.7 0.0 2.1 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.6 OAP55160.1 - 3e-05 24.5 0.0 0.00017 22.0 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.22 OAP55160.1 - 0.00041 19.6 0.0 0.00072 18.8 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain RNA_helicase PF00910.22 OAP55160.1 - 0.0053 17.1 0.1 0.02 15.3 0.0 2.0 2 0 0 2 2 2 1 RNA helicase PNP_UDP_1 PF01048.20 OAP55160.1 - 0.022 14.0 0.1 0.066 12.4 0.0 1.8 2 0 0 2 2 2 0 Phosphorylase superfamily AAA PF00004.29 OAP55160.1 - 0.17 12.3 0.0 0.44 11.0 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) IDO PF01231.18 OAP55162.1 - 4.8e-101 338.7 0.0 6.8e-100 334.9 0.0 2.1 1 1 0 1 1 1 1 Indoleamine 2,3-dioxygenase Trp_dioxygenase PF03301.13 OAP55162.1 - 0.1 11.9 0.8 4.3 6.6 0.1 2.5 1 1 1 2 2 2 0 Tryptophan 2,3-dioxygenase bZIP_1 PF00170.21 OAP55164.1 - 3.2e-07 30.3 9.4 5e-07 29.7 9.4 1.3 1 0 0 1 1 1 1 bZIP transcription factor DivIC PF04977.15 OAP55164.1 - 2.9 7.7 9.0 0.99 9.2 0.9 2.2 1 1 1 2 2 2 0 Septum formation initiator SNF2_N PF00176.23 OAP55165.1 - 9.1e-62 208.8 0.0 1.7e-61 207.9 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-C3HC4_3 PF13920.6 OAP55165.1 - 6.5e-08 32.3 8.8 1.9e-07 30.8 8.8 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OAP55165.1 - 1.9e-07 30.8 10.8 1.9e-07 30.8 10.8 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAP55165.1 - 2.8e-07 30.8 10.7 8.6e-07 29.2 10.7 1.9 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 OAP55165.1 - 3.8e-07 29.9 8.3 8.5e-07 28.7 8.3 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 OAP55165.1 - 5.6e-06 26.1 10.7 1.7e-05 24.5 10.7 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Helicase_C PF00271.31 OAP55165.1 - 3.7e-05 24.0 0.1 0.00012 22.3 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-RING_UBOX PF13445.6 OAP55165.1 - 0.00018 21.4 4.6 0.00097 19.1 4.8 2.3 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 OAP55165.1 - 0.00026 20.9 10.0 0.00026 20.9 10.0 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 OAP55165.1 - 0.014 15.5 9.0 0.033 14.3 9.0 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-UDP PF14569.6 OAP55165.1 - 0.048 13.8 2.3 0.2 11.8 2.3 2.0 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-P11 PF03854.14 OAP55165.1 - 0.25 11.0 7.4 0.6 9.8 7.4 1.6 1 0 0 1 1 1 0 P-11 zinc finger zf-rbx1 PF12678.7 OAP55165.1 - 0.28 11.5 8.9 1.1 9.6 8.9 2.0 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_6 PF14835.6 OAP55165.1 - 2.3 8.2 4.5 5.6 6.9 4.5 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein SGL PF08450.12 OAP55167.1 - 0.00022 20.9 1.7 0.07 12.7 0.1 2.9 3 1 0 3 3 3 2 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 OAP55167.1 - 0.043 13.9 0.0 9 6.5 0.0 3.3 2 0 0 2 2 2 0 NHL repeat SBBP PF06739.11 OAP55167.1 - 0.068 13.2 0.0 17 5.5 0.0 2.7 2 0 0 2 2 2 0 Beta-propeller repeat GSDH PF07995.11 OAP55167.1 - 0.11 11.8 0.1 0.91 8.8 0.1 2.3 2 0 0 2 2 2 0 Glucose / Sorbosone dehydrogenase Arylesterase PF01731.20 OAP55167.1 - 0.13 12.5 0.0 21 5.4 0.0 2.9 3 0 0 3 3 3 0 Arylesterase ABC_tran PF00005.27 OAP55168.1 - 5.4e-47 159.8 1.0 3.3e-22 79.5 0.0 3.0 3 0 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 OAP55168.1 - 2.4e-21 75.5 6.1 2.4e-21 75.5 6.1 4.0 5 0 0 5 5 4 1 ABC transporter AAA_21 PF13304.6 OAP55168.1 - 5.4e-15 56.0 4.5 0.0032 17.3 0.1 5.1 6 0 0 6 6 6 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OAP55168.1 - 9.3e-11 41.6 0.7 0.027 13.9 0.0 4.5 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 OAP55168.1 - 1.2e-06 28.9 0.0 0.0072 16.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 OAP55168.1 - 1.2e-06 28.5 1.7 0.038 13.9 0.0 3.0 3 0 0 3 3 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OAP55168.1 - 6.4e-06 26.2 0.0 0.048 13.7 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.6 OAP55168.1 - 8.9e-06 26.3 15.8 0.028 14.9 0.0 5.1 5 0 0 5 5 5 2 AAA domain AAA_16 PF13191.6 OAP55168.1 - 1.1e-05 25.9 1.2 0.11 12.8 0.2 3.1 3 0 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.6 OAP55168.1 - 1.6e-05 24.5 1.2 0.14 11.9 0.0 3.1 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_33 PF13671.6 OAP55168.1 - 8.9e-05 22.7 1.7 0.22 11.7 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_15 PF13175.6 OAP55168.1 - 9.7e-05 22.2 10.3 0.33 10.6 0.0 4.7 4 1 0 4 4 4 2 AAA ATPase domain AAA_24 PF13479.6 OAP55168.1 - 0.00017 21.4 2.4 0.55 9.9 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_18 PF13238.6 OAP55168.1 - 0.00022 21.8 4.2 0.31 11.6 0.0 3.2 4 0 0 4 4 2 2 AAA domain AAA_30 PF13604.6 OAP55168.1 - 0.00025 20.8 0.1 0.039 13.7 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA PF00004.29 OAP55168.1 - 0.00086 19.7 0.1 0.8 10.1 0.1 3.2 3 1 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 OAP55168.1 - 0.0021 18.1 0.0 3.3 7.8 0.0 3.1 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 OAP55168.1 - 0.0026 17.7 0.7 0.85 9.5 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_28 PF13521.6 OAP55168.1 - 0.0037 17.5 5.8 0.13 12.5 0.1 3.0 3 0 0 3 3 2 1 AAA domain RNA_helicase PF00910.22 OAP55168.1 - 0.0053 17.1 0.0 2.9 8.3 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_27 PF13514.6 OAP55168.1 - 0.0071 16.0 1.5 5.3 6.6 0.0 3.4 4 0 0 4 4 2 0 AAA domain MobB PF03205.14 OAP55168.1 - 0.015 15.2 0.1 0.43 10.5 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.12 OAP55168.1 - 0.018 14.3 0.9 3.7 6.8 0.0 2.9 3 0 0 3 3 3 0 Zeta toxin NTPase_1 PF03266.15 OAP55168.1 - 0.019 14.9 0.0 1.8 8.5 0.0 2.7 2 0 0 2 2 2 0 NTPase MeaB PF03308.16 OAP55168.1 - 0.022 13.7 4.8 2 7.3 0.1 3.0 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Rad17 PF03215.15 OAP55168.1 - 0.026 14.4 0.1 3.8 7.4 0.0 3.1 2 1 1 3 3 3 0 Rad17 P-loop domain Roc PF08477.13 OAP55168.1 - 0.031 14.5 0.1 7.1 6.9 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 OAP55168.1 - 0.043 13.4 3.0 1.1 8.8 0.5 2.9 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 OAP55168.1 - 0.048 13.2 0.0 6.5 6.2 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region ATP-synt_ab PF00006.25 OAP55168.1 - 0.048 13.3 0.1 1.3 8.6 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain TsaE PF02367.17 OAP55168.1 - 0.061 13.3 0.0 11 6.1 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_5 PF07728.14 OAP55168.1 - 0.064 13.3 0.1 7.9 6.5 0.0 2.8 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 OAP55168.1 - 0.072 12.3 0.1 13 4.9 0.0 2.6 2 0 0 2 2 2 0 NB-ARC domain DUF3584 PF12128.8 OAP55168.1 - 0.08 10.5 0.1 0.08 10.5 0.1 3.9 5 0 0 5 5 5 0 Protein of unknown function (DUF3584) Dynamin_N PF00350.23 OAP55168.1 - 0.11 12.6 9.3 2.6 8.1 0.0 3.9 3 1 0 4 4 4 0 Dynamin family DUF87 PF01935.17 OAP55168.1 - 1 9.4 12.6 2.9 7.9 0.0 4.5 5 0 0 5 5 4 0 Helicase HerA, central domain ESSS PF10183.9 OAP55170.1 - 1.3e-07 31.8 0.2 1.9e-07 31.3 0.2 1.2 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) CbtA PF09490.10 OAP55170.1 - 0.039 13.7 0.2 0.051 13.3 0.2 1.1 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) SelP_N PF04592.14 OAP55170.1 - 5.7 6.3 7.1 58 3.0 0.0 2.1 1 1 0 2 2 2 0 Selenoprotein P, N terminal region Raffinose_syn PF05691.12 OAP55171.1 - 1.7e-55 188.2 0.9 3.2e-53 180.7 0.9 2.9 1 1 0 1 1 1 1 Raffinose synthase or seed imbibition protein Sip1 Melibiase PF02065.18 OAP55171.1 - 0.054 12.4 0.1 0.087 11.8 0.1 1.2 1 0 0 1 1 1 0 Melibiase Abhydrolase_6 PF12697.7 OAP55173.1 - 2.5e-11 44.6 0.2 4e-11 43.9 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAP55173.1 - 4.1e-09 36.1 0.0 6.9e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OAP55173.1 - 2.3e-06 27.4 0.2 8.2e-06 25.6 0.2 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 OAP55173.1 - 0.00026 20.9 0.0 0.00039 20.4 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Mitofilin PF09731.9 OAP55175.1 - 9.2e-141 470.7 23.2 8.7e-140 467.5 23.2 1.9 1 1 0 1 1 1 1 Mitochondrial inner membrane protein DUF4559 PF15112.6 OAP55175.1 - 0.021 14.5 7.1 0.035 13.8 7.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) HsbA PF12296.8 OAP55175.1 - 0.061 13.8 3.2 0.079 13.4 0.6 2.4 2 0 0 2 2 2 0 Hydrophobic surface binding protein A YqhG PF11079.8 OAP55175.1 - 0.25 10.3 1.9 0.41 9.6 1.9 1.2 1 0 0 1 1 1 0 Bacterial protein YqhG of unknown function Focal_AT PF03623.13 OAP55175.1 - 4.2 7.4 6.2 4.4 7.3 0.5 2.4 1 1 1 2 2 2 0 Focal adhesion targeting region Cytochrom_B562 PF07361.11 OAP55175.1 - 7.2 7.3 13.6 12 6.6 5.4 3.8 2 1 0 3 3 3 0 Cytochrome b562 Pescadillo_N PF06732.11 OAP55176.1 - 4e-119 397.2 0.3 4e-119 397.2 0.3 1.6 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT_2 PF16589.5 OAP55176.1 - 3.7e-05 24.1 0.1 0.0004 20.7 0.1 2.5 1 1 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 OAP55176.1 - 0.00018 21.8 0.0 0.0017 18.7 0.0 2.5 2 1 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PIG-U PF06728.13 OAP55177.1 - 1.1e-104 350.6 24.1 1.3e-104 350.3 24.1 1.1 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U 8TM_micro PF17028.5 OAP55177.1 - 0.011 15.5 5.7 0.011 15.5 5.7 1.4 1 1 0 1 1 1 0 8TM Microsporidial transmembrane domain Acetyltransf_1 PF00583.25 OAP55178.1 - 3e-09 37.1 0.0 4e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OAP55178.1 - 7.2e-06 26.0 0.0 1.1e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OAP55178.1 - 9.5e-05 22.7 0.0 0.00017 22.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 OAP55178.1 - 0.031 14.4 0.0 0.053 13.6 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_15 PF17013.5 OAP55178.1 - 0.038 13.5 0.1 0.052 13.0 0.1 1.3 1 0 0 1 1 1 0 Putative acetyl-transferase Aldedh PF00171.22 OAP55179.1 - 1.9e-165 550.9 0.4 2.1e-165 550.7 0.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Dynamin_N PF00350.23 OAP55180.1 - 2.7e-06 27.5 0.0 5.5e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 OAP55180.1 - 0.00034 20.7 0.1 0.0059 16.7 0.1 2.6 2 1 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OAP55180.1 - 0.00065 19.6 0.2 0.025 14.5 0.0 2.6 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 OAP55180.1 - 0.0081 16.6 0.0 0.027 14.9 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 OAP55180.1 - 0.018 15.6 0.0 0.063 13.8 0.0 1.9 1 0 0 1 1 1 0 ABC transporter AIG1 PF04548.16 OAP55180.1 - 0.034 13.5 0.1 0.33 10.3 0.1 2.1 2 0 0 2 2 2 0 AIG1 family CCDC24 PF15669.5 OAP55180.1 - 0.036 13.9 0.0 0.085 12.7 0.0 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family AAA_22 PF13401.6 OAP55180.1 - 0.074 13.3 0.1 1 9.6 0.0 2.7 2 1 1 3 3 3 0 AAA domain ABC_tran_CTD PF16326.5 OAP55180.1 - 0.13 12.6 0.6 0.57 10.5 0.6 2.2 1 0 0 1 1 1 0 ABC transporter C-terminal domain Ank_2 PF12796.7 OAP55181.1 - 2.9e-82 271.3 0.5 6.2e-14 52.3 0.0 6.7 2 2 6 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAP55181.1 - 1.2e-74 245.8 0.4 5.9e-11 42.7 0.0 12.7 2 2 11 13 13 13 13 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAP55181.1 - 2.7e-59 190.1 0.0 8.2e-05 22.7 0.0 15.0 15 0 0 15 15 15 13 Ankyrin repeat Ank PF00023.30 OAP55181.1 - 9.9e-58 190.2 6.5 0.002 18.5 0.0 15.1 14 1 1 15 15 15 13 Ankyrin repeat Ank_5 PF13857.6 OAP55181.1 - 3.7e-54 180.1 2.5 8.3e-09 35.6 0.0 10.0 3 3 9 12 12 12 9 Ankyrin repeats (many copies) Shigella_OspC PF06128.11 OAP55181.1 - 0.00057 19.7 0.2 1.3 8.7 0.0 4.3 4 2 1 5 5 5 1 Shigella flexneri OspC protein DUF4646 PF15496.6 OAP55181.1 - 0.096 13.3 2.7 4.2 8.0 0.1 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4646) Sugar_tr PF00083.24 OAP55182.1 - 9.6e-86 288.4 27.0 1.1e-85 288.2 27.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP55182.1 - 3.5e-20 72.2 38.5 1.1e-13 50.8 10.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF697 PF05128.12 OAP55182.1 - 0.2 11.4 0.6 0.37 10.5 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF697) Aldedh PF00171.22 OAP55183.1 - 2.1e-151 504.6 0.1 2.3e-151 504.4 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family RuvA_C PF07499.13 OAP55183.1 - 0.65 10.5 3.9 1.4 9.4 2.1 2.3 2 0 0 2 2 2 0 RuvA, C-terminal domain DUF4880 PF16220.5 OAP55183.1 - 0.74 9.8 3.2 1.4 8.9 3.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4880) TPP_enzyme_N PF02776.18 OAP55184.1 - 1.8e-33 115.6 0.0 7.6e-31 107.0 0.0 2.5 2 1 0 2 2 2 2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 OAP55184.1 - 3.9e-14 52.7 0.0 7.9e-14 51.7 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 OAP55184.1 - 1.8e-11 44.0 0.0 3.4e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain Fungal_trans PF04082.18 OAP55185.1 - 8.8e-31 106.9 0.1 1.4e-30 106.3 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP55185.1 - 9.6e-08 32.0 8.8 1.8e-07 31.1 8.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldedh PF00171.22 OAP55186.1 - 2.4e-171 570.3 0.3 3e-171 570.0 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family FMO-like PF00743.19 OAP55187.1 - 8.8e-17 60.7 0.0 2e-16 59.5 0.0 1.5 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OAP55187.1 - 3.5e-16 59.3 0.0 3.9e-15 55.9 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAP55187.1 - 5.8e-10 38.9 0.0 1.2e-08 34.5 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAP55187.1 - 2.4e-09 36.8 0.1 5.7e-08 32.3 0.0 2.5 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 OAP55187.1 - 1.5e-07 31.5 0.1 4.9e-06 26.7 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAP55187.1 - 7.3e-05 22.5 0.6 0.3 10.6 0.3 2.4 1 1 1 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OAP55187.1 - 0.0018 17.4 0.0 0.0031 16.7 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain 2-Hacid_dh_C PF02826.19 OAP55187.1 - 0.0031 16.9 0.0 0.0064 15.9 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 OAP55187.1 - 0.0089 16.1 0.0 0.045 13.8 0.0 2.0 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.17 OAP55187.1 - 0.01 15.1 0.7 0.016 14.4 0.0 1.7 2 0 0 2 2 2 0 Thi4 family Pyr_redox PF00070.27 OAP55187.1 - 0.053 14.1 0.2 14 6.4 0.1 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 OAP55187.1 - 0.16 12.5 0.0 1.4 9.4 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding FAD_binding_3 PF01494.19 OAP55187.1 - 0.18 11.0 1.9 1.1 8.5 0.3 2.8 3 1 1 4 4 4 0 FAD binding domain NAD_binding_2 PF03446.15 OAP55187.1 - 0.22 11.7 0.0 0.49 10.6 0.0 1.6 2 0 0 2 2 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Sugar_tr PF00083.24 OAP55188.1 - 1.4e-80 271.4 21.0 1.6e-80 271.2 21.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP55188.1 - 3.5e-23 82.1 45.9 4.3e-22 78.5 19.8 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Rick_17kDa_Anti PF05433.15 OAP55188.1 - 0.0086 15.9 1.1 0.033 14.0 1.1 2.0 1 0 0 1 1 1 1 Glycine zipper 2TM domain FAM60A PF15396.6 OAP55188.1 - 0.29 11.1 0.0 0.54 10.2 0.0 1.4 1 0 0 1 1 1 0 Protein Family FAM60A 4HBT PF03061.22 OAP55189.1 - 4.5e-06 26.9 0.0 9.1e-06 25.9 0.0 1.5 2 0 0 2 2 2 1 Thioesterase superfamily MARVEL PF01284.23 OAP55190.1 - 3.3e-10 40.2 12.9 4.3e-10 39.8 12.9 1.2 1 0 0 1 1 1 1 Membrane-associating domain MIP PF00230.20 OAP55191.1 - 5.3e-46 157.2 12.8 7.1e-46 156.7 12.8 1.1 1 0 0 1 1 1 1 Major intrinsic protein Fungal_trans PF04082.18 OAP55192.1 - 1.3e-11 44.0 0.0 2.3e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Acyl-CoA_ox_N PF14749.6 OAP55193.1 - 1.7e-20 73.8 0.7 3.1e-20 73.0 0.7 1.5 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal ACOX PF01756.19 OAP55193.1 - 7.6e-13 48.4 0.3 2.1e-12 47.0 0.1 1.7 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.19 OAP55193.1 - 3.6e-09 36.7 0.0 7.6e-09 35.7 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 OAP55193.1 - 0.0027 17.9 0.0 0.0054 17.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Fuseless PF15993.5 OAP55193.1 - 0.02 14.1 0.1 0.032 13.4 0.1 1.2 1 0 0 1 1 1 0 Fuseless ECH_1 PF00378.20 OAP55194.1 - 5.8e-31 107.7 0.0 6.8e-31 107.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAP55194.1 - 1.2e-13 51.3 0.0 1.4e-13 51.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase AMP-binding PF00501.28 OAP55195.1 - 9.3e-50 169.4 0.0 1.2e-49 169.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAP55195.1 - 7e-13 49.4 0.1 2.1e-12 47.8 0.1 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain CAMSAP_CH PF11971.8 OAP55195.1 - 0.092 12.6 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 CAMSAP CH domain MFS_1 PF07690.16 OAP55196.1 - 1.1e-28 100.2 28.6 1.1e-28 100.2 28.6 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily ACOX PF01756.19 OAP55197.1 - 4.8e-41 140.3 0.6 9.6e-41 139.3 0.2 1.7 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 OAP55197.1 - 6.1e-22 78.5 0.3 1.5e-21 77.3 0.2 1.8 2 0 0 2 2 2 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 OAP55197.1 - 5e-07 29.8 0.0 1.3e-06 28.5 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 OAP55197.1 - 0.01 16.0 0.2 3 8.0 0.0 2.3 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain Aconitase PF00330.20 OAP55199.1 - 5.2e-70 236.7 0.1 4.3e-69 233.7 0.1 1.9 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 OAP55199.1 - 3.8e-19 69.3 0.0 6.7e-19 68.5 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Sugar_tr PF00083.24 OAP55200.1 - 2.6e-87 293.6 19.5 2.9e-87 293.4 19.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP55200.1 - 2.5e-27 95.7 49.7 2.5e-25 89.2 26.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 OAP55200.1 - 0.00054 18.5 0.2 0.00054 18.5 0.2 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) BT1 PF03092.16 OAP55200.1 - 0.0071 14.6 4.8 0.12 10.5 0.2 2.8 2 1 1 3 3 3 2 BT1 family Csm1_B PF18211.1 OAP55200.1 - 0.079 12.8 0.2 0.33 10.8 0.1 2.1 2 0 0 2 2 2 0 Csm1 subunit domain B Fungal_trans PF04082.18 OAP55201.1 - 2.8e-10 39.7 0.2 1.2e-09 37.6 0.0 2.1 2 1 1 3 3 3 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 OAP55201.1 - 8.4e-07 29.1 11.5 3.8e-06 27.0 3.6 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OAP55201.1 - 3.3e-06 27.3 9.1 0.00045 20.5 2.5 2.6 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 OAP55201.1 - 0.00033 21.3 9.3 0.0058 17.4 2.5 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 OAP55201.1 - 0.37 11.0 2.6 0.96 9.6 2.6 1.7 1 0 0 1 1 1 0 Zinc ribbon domain zf-LYAR PF08790.11 OAP55201.1 - 0.51 10.3 7.3 2.6 8.0 0.4 2.5 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger TPR_2 PF07719.17 OAP55202.1 - 5.5e-10 38.6 11.1 0.00054 19.9 0.0 6.8 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_1 PF00515.28 OAP55202.1 - 1.6e-07 30.8 2.0 0.017 14.9 0.0 5.8 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 OAP55202.1 - 1e-06 29.1 6.5 0.0039 17.7 0.0 4.7 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 OAP55202.1 - 0.00082 19.4 4.0 1.8 9.0 0.0 6.2 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_11 PF13414.6 OAP55202.1 - 0.0012 18.5 0.9 0.29 10.8 0.0 4.4 6 0 0 6 6 6 1 TPR repeat TPR_17 PF13431.6 OAP55202.1 - 0.0053 17.1 2.1 1.8e+02 2.9 0.0 6.3 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 OAP55202.1 - 0.0055 17.0 8.4 4.3 7.7 0.3 5.9 6 1 0 6 6 6 1 Tetratricopeptide repeat TPR_16 PF13432.6 OAP55202.1 - 0.052 14.2 20.1 7.2 7.3 0.0 6.6 6 1 0 6 6 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 OAP55202.1 - 0.075 13.1 3.3 16 5.8 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 OAP55202.1 - 0.098 12.6 1.1 1.2e+02 2.8 0.1 4.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 OAP55202.1 - 0.23 12.4 22.6 11 7.1 0.1 8.1 8 2 1 9 9 8 0 Tetratricopeptide repeat TPR_4 PF07721.14 OAP55202.1 - 1.4 9.7 14.8 5.3 8.0 0.0 5.4 6 0 0 6 6 4 0 Tetratricopeptide repeat Abhydrolase_6 PF12697.7 OAP55204.1 - 6.7e-09 36.7 0.2 1e-08 36.1 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAP55204.1 - 3e-05 23.8 0.0 4.7e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2293 PF10056.9 OAP55204.1 - 0.0083 16.4 0.0 4.5 7.6 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2293) Thioesterase PF00975.20 OAP55204.1 - 0.054 13.6 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain Sugar_tr PF00083.24 OAP55206.1 - 7.5e-83 278.9 19.7 8.6e-83 278.7 19.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP55206.1 - 7.5e-24 84.3 39.4 5.3e-19 68.4 13.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily PUCC PF03209.15 OAP55206.1 - 0.0098 14.9 7.7 0.02 13.9 7.7 1.5 1 0 0 1 1 1 1 PUCC protein MFS_1 PF07690.16 OAP55207.1 - 4.9e-37 127.7 51.4 5e-37 127.6 41.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAP55207.1 - 2.4e-10 39.9 12.7 2.4e-10 39.9 12.7 3.3 2 2 1 3 3 3 1 Sugar (and other) transporter MWFE PF15879.5 OAP55207.1 - 0.92 9.7 0.0 0.92 9.7 0.0 3.1 4 0 0 4 4 4 0 NADH-ubiquinone oxidoreductase MWFE subunit CN_hydrolase PF00795.22 OAP55208.1 - 2.5e-47 161.4 0.0 3.2e-47 161.1 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase ADH_zinc_N PF00107.26 OAP55209.1 - 1.6e-28 99.3 1.0 1.8e-28 99.1 0.2 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAP55209.1 - 2e-17 63.1 0.2 4e-17 62.1 0.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 OAP55209.1 - 0.00018 22.6 0.1 0.00031 21.8 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 OAP55209.1 - 0.0021 17.9 0.1 0.01 15.7 0.0 2.2 2 1 0 2 2 2 1 N-terminal domain of oxidoreductase AlaDh_PNT_C PF01262.21 OAP55209.1 - 0.017 14.4 0.3 0.027 13.8 0.3 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain adh_short PF00106.25 OAP55209.1 - 0.02 14.4 0.3 0.036 13.5 0.3 1.5 1 0 0 1 1 1 0 short chain dehydrogenase EBP PF05241.12 OAP55209.1 - 0.16 11.4 0.0 0.24 10.8 0.0 1.2 1 0 0 1 1 1 0 Emopamil binding protein Glyco_trans_2_3 PF13632.6 OAP55210.1 - 2.5e-50 171.2 2.9 5.6e-50 170.0 2.9 1.6 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 OAP55210.1 - 0.00038 20.3 0.0 0.0018 18.1 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 OAP55210.1 - 0.14 11.6 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 21 Glyco_hydro_16 PF00722.21 OAP55211.1 - 9.6e-18 64.3 0.5 1.5e-17 63.7 0.5 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Citrate_synt PF00285.21 OAP55212.1 - 1.5e-94 317.0 0.0 1.9e-94 316.7 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain ICL PF00463.21 OAP55213.1 - 2.2e-189 630.3 0.0 2.5e-189 630.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 OAP55213.1 - 2.4e-08 33.7 0.0 4.2e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ABC_tran PF00005.27 OAP55214.1 - 1.2e-48 165.1 0.1 2.7e-26 92.7 0.0 4.1 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 OAP55214.1 - 1.8e-14 54.3 1.5 0.0022 17.9 0.0 4.4 3 1 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OAP55214.1 - 6.7e-12 45.3 0.1 0.0033 16.9 0.0 4.1 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 OAP55214.1 - 1.7e-08 35.2 1.5 0.00041 20.9 0.1 2.7 3 0 0 3 3 2 2 AAA domain Chromo PF00385.24 OAP55214.1 - 7.5e-08 32.2 0.2 1.6e-07 31.1 0.2 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain MMR_HSR1 PF01926.23 OAP55214.1 - 2e-07 31.1 0.0 0.0025 17.9 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OAP55214.1 - 4.8e-07 29.8 0.2 0.003 17.5 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 OAP55214.1 - 7.2e-07 28.9 0.5 0.011 15.5 0.2 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_28 PF13521.6 OAP55214.1 - 5.3e-05 23.5 0.0 0.0096 16.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 OAP55214.1 - 0.00012 22.4 0.2 0.71 10.1 0.1 3.1 2 1 0 2 2 2 2 AAA domain DUF87 PF01935.17 OAP55214.1 - 0.00019 21.6 0.4 0.11 12.6 0.1 3.1 3 0 0 3 3 2 1 Helicase HerA, central domain AAA_18 PF13238.6 OAP55214.1 - 0.00022 21.8 0.2 0.15 12.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 OAP55214.1 - 0.00026 20.8 0.2 0.21 11.2 0.2 2.4 2 0 0 2 2 2 2 AAA ATPase domain MeaB PF03308.16 OAP55214.1 - 0.00034 19.7 0.3 0.11 11.4 0.1 2.5 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB NACHT PF05729.12 OAP55214.1 - 0.00053 19.9 1.5 0.54 10.2 0.0 3.5 4 0 0 4 4 3 1 NACHT domain CLASP_N PF12348.8 OAP55214.1 - 0.0013 18.3 0.0 0.037 13.6 0.0 2.5 2 0 0 2 2 2 1 CLASP N terminal SR-25 PF10500.9 OAP55214.1 - 0.0014 18.3 2.0 0.0027 17.3 2.0 1.4 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein AAA_13 PF13166.6 OAP55214.1 - 0.0037 16.0 0.0 1.4 7.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 OAP55214.1 - 0.0043 17.2 0.0 5.8 7.1 0.0 2.8 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 OAP55214.1 - 0.0074 16.7 0.1 5.5 7.4 0.0 2.8 2 0 0 2 2 2 0 RNA helicase DUF3584 PF12128.8 OAP55214.1 - 0.0089 13.6 1.2 0.61 7.5 0.1 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3584) AAA_14 PF13173.6 OAP55214.1 - 0.011 15.8 0.0 7.3 6.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 OAP55214.1 - 0.011 15.8 0.0 0.27 11.3 0.0 2.7 2 1 0 2 2 2 0 Dynamin family SbcCD_C PF13558.6 OAP55214.1 - 0.012 15.9 0.1 6.1 7.2 0.0 3.2 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 OAP55214.1 - 0.013 15.3 0.4 9.8 5.8 0.0 3.1 3 0 0 3 3 2 0 AAA domain DUF815 PF05673.13 OAP55214.1 - 0.014 14.6 0.4 0.44 9.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_24 PF13479.6 OAP55214.1 - 0.023 14.4 0.5 1.9 8.2 0.1 2.6 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 OAP55214.1 - 0.025 14.3 0.1 0.78 9.5 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 OAP55214.1 - 0.031 14.7 0.1 4.3 7.7 0.0 3.0 3 0 0 3 3 2 0 AAA ATPase domain NB-ARC PF00931.22 OAP55214.1 - 0.032 13.4 0.5 7.8 5.6 0.0 3.2 3 0 0 3 3 3 0 NB-ARC domain Roc PF08477.13 OAP55214.1 - 0.033 14.4 0.1 5.7 7.2 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_27 PF13514.6 OAP55214.1 - 0.041 13.5 1.2 11 5.6 0.0 2.9 3 0 0 3 3 3 0 AAA domain Zeta_toxin PF06414.12 OAP55214.1 - 0.054 12.8 0.7 4.5 6.5 0.1 3.0 3 0 0 3 3 3 0 Zeta toxin HEAT PF02985.22 OAP55214.1 - 0.067 13.5 0.0 86 3.8 0.0 4.9 5 0 0 5 5 4 0 HEAT repeat AAA PF00004.29 OAP55214.1 - 0.071 13.5 0.0 12 6.3 0.0 3.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Septin PF00735.18 OAP55214.1 - 0.082 12.2 0.0 6.9 5.9 0.0 2.5 2 0 0 2 2 2 0 Septin Ploopntkinase3 PF18751.1 OAP55214.1 - 0.085 12.8 0.0 20 5.0 0.0 2.5 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 TsaE PF02367.17 OAP55214.1 - 0.14 12.2 0.4 14 5.7 0.1 2.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Ala_racemase_N PF01168.20 OAP55215.1 - 4.8e-18 65.6 0.0 9.1e-18 64.7 0.0 1.4 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Adaptin_N PF01602.20 OAP55216.1 - 4.6e-127 424.8 7.3 6e-127 424.4 7.3 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 OAP55216.1 - 5.5e-42 142.5 0.0 1.5e-41 141.2 0.0 1.8 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.20 OAP55216.1 - 9.4e-17 61.3 0.0 1.7e-16 60.5 0.0 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 OAP55216.1 - 0.0001 22.4 1.2 0.0021 18.1 0.1 2.9 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 OAP55216.1 - 0.032 14.4 0.2 1.1 9.5 0.1 3.4 4 0 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 ISN1 PF06437.11 OAP55217.1 - 3.8e-154 513.5 0.0 4.3e-154 513.4 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase ADH_zinc_N PF00107.26 OAP55218.1 - 6.1e-09 35.9 0.1 1.1e-08 35.1 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAP55218.1 - 3.6e-08 33.2 0.0 8.8e-08 32.0 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 OAP55218.1 - 9.4e-06 25.2 0.5 1.5e-05 24.5 0.5 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Fungal_trans PF04082.18 OAP55219.1 - 1.5e-10 40.6 0.0 2.2e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Med17 PF10156.9 OAP55220.1 - 1.5e-85 287.6 0.0 2.2e-85 287.1 0.0 1.1 1 0 0 1 1 1 1 Subunit 17 of Mediator complex PFK PF00365.20 OAP55221.1 - 6.8e-194 642.5 0.2 1.1e-106 356.3 0.2 2.1 2 0 0 2 2 2 2 Phosphofructokinase DAGK_cat PF00781.24 OAP55221.1 - 0.075 12.7 0.1 0.22 11.2 0.1 1.7 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain UVR PF02151.19 OAP55221.1 - 0.14 12.0 0.2 0.37 10.6 0.2 1.7 1 0 0 1 1 1 0 UvrB/uvrC motif Sugar_tr PF00083.24 OAP55223.1 - 2.8e-39 135.3 17.8 6.4e-26 91.2 2.4 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 OAP55223.1 - 1.4e-22 80.1 22.7 2.5e-22 79.3 20.4 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily zf-C2H2_4 PF13894.6 OAP55225.1 - 7.4 7.7 11.0 16 6.6 0.8 3.8 3 0 0 3 3 3 0 C2H2-type zinc finger efThoc1 PF11957.8 OAP55226.1 - 2e-135 452.3 0.1 2.5e-135 451.9 0.1 1.1 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor Aquarius_N PF16399.5 OAP55227.1 - 3e-293 974.8 0.0 4.1e-293 974.3 0.0 1.1 1 0 0 1 1 1 1 Intron-binding protein aquarius N-terminus AAA_12 PF13087.6 OAP55227.1 - 1.3e-24 87.0 0.0 2.3e-24 86.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 OAP55227.1 - 6.6e-23 81.8 0.0 1.4e-22 80.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OAP55227.1 - 5.2e-07 30.1 0.0 1.5e-06 28.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 OAP55227.1 - 1.6e-06 27.9 0.0 0.00053 19.8 0.0 2.6 2 1 0 2 2 2 1 AAA domain ResIII PF04851.15 OAP55227.1 - 2.2e-06 27.8 0.0 6.5e-06 26.2 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_16 PF13191.6 OAP55227.1 - 0.0023 18.3 0.5 0.012 16.0 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain UvrD-helicase PF00580.21 OAP55227.1 - 0.0057 16.2 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA PF00004.29 OAP55227.1 - 0.021 15.3 0.0 0.062 13.7 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) UvrD_C_2 PF13538.6 OAP55227.1 - 0.026 14.3 3.1 0.044 13.6 0.2 2.7 3 0 0 3 3 3 0 UvrD-like helicase C-terminal domain AAA_5 PF07728.14 OAP55227.1 - 0.05 13.6 0.0 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Adeno_IVa2 PF02456.15 OAP55227.1 - 0.061 12.1 0.8 4.4 6.0 0.2 2.3 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_22 PF13401.6 OAP55227.1 - 0.077 13.3 0.0 0.31 11.3 0.0 2.0 2 0 0 2 2 1 0 AAA domain DnaB_C PF03796.15 OAP55227.1 - 0.11 11.8 0.0 0.23 10.7 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain GMC_oxred_N PF00732.19 OAP55228.1 - 3.4e-63 213.8 0.0 4.7e-63 213.3 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAP55228.1 - 1.7e-30 106.4 0.0 3.1e-30 105.6 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 OAP55228.1 - 2.4e-05 23.6 0.0 4.1e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 OAP55228.1 - 0.00012 21.4 0.1 0.00057 19.2 0.0 2.0 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 OAP55228.1 - 0.00034 20.3 0.9 0.063 12.8 0.3 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OAP55228.1 - 0.00066 18.9 0.5 0.0083 15.2 0.2 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 OAP55228.1 - 0.012 15.8 0.1 0.032 14.5 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 OAP55228.1 - 0.029 13.2 0.1 0.042 12.7 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase FAD_oxidored PF12831.7 OAP55228.1 - 0.037 13.4 0.7 4.4 6.5 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAP55228.1 - 0.048 12.9 0.4 0.18 11.0 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Translin PF01997.16 OAP55231.1 - 1.6e-46 158.9 0.2 2.1e-46 158.5 0.2 1.0 1 0 0 1 1 1 1 Translin family HR1 PF02185.16 OAP55231.1 - 0.13 12.4 2.7 0.12 12.5 1.0 2.0 2 1 0 2 2 2 0 Hr1 repeat MMR_HSR1_C PF08438.10 OAP55234.1 - 1.2e-36 125.7 0.0 1.9e-36 125.0 0.0 1.4 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.23 OAP55234.1 - 2.3e-20 72.8 0.0 6.4e-20 71.3 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OAP55234.1 - 6.3e-09 35.5 0.0 1.3e-07 31.3 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 OAP55234.1 - 0.012 15.1 0.1 1.9 8.0 0.1 2.6 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_33 PF13671.6 OAP55234.1 - 0.033 14.4 0.1 8 6.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 OAP55234.1 - 0.048 13.7 0.5 0.15 12.1 0.3 1.9 2 0 0 2 2 2 0 Dynamin family AAA_18 PF13238.6 OAP55234.1 - 0.12 12.9 0.1 3.5 8.2 0.0 2.5 2 1 0 2 2 2 0 AAA domain Ploopntkinase3 PF18751.1 OAP55234.1 - 0.13 12.2 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 KTI12 PF08433.10 OAP55234.1 - 0.15 11.5 0.0 0.28 10.6 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 adh_short PF00106.25 OAP55235.1 - 6.7e-87 290.0 14.0 1.1e-44 152.2 2.1 3.3 3 1 0 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAP55235.1 - 1.1e-66 224.7 12.2 9.7e-34 116.9 2.4 3.0 2 2 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP55235.1 - 1.9e-32 112.6 4.7 1.7e-15 57.4 0.3 2.5 2 0 0 2 2 2 2 KR domain MaoC_dehydratas PF01575.19 OAP55235.1 - 2.8e-26 91.5 0.0 5.8e-26 90.5 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain Fungal_trans PF04082.18 OAP55236.1 - 1.4e-41 142.3 2.7 2.3e-41 141.6 2.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP55236.1 - 5.7e-08 32.7 14.7 9.8e-08 32.0 14.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Lzipper-MIP1 PF14389.6 OAP55236.1 - 0.012 15.8 2.8 0.019 15.2 1.1 2.2 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 NYD-SP28 PF14772.6 OAP55236.1 - 0.048 13.7 0.8 0.28 11.3 0.1 2.3 2 0 0 2 2 2 0 Sperm tail bZIP_1 PF00170.21 OAP55236.1 - 0.14 12.2 0.1 0.62 10.2 0.1 2.1 1 0 0 1 1 1 0 bZIP transcription factor DUF4383 PF14325.6 OAP55236.1 - 0.15 12.4 0.7 2.2 8.6 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4383) SET PF00856.28 OAP55237.1 - 0.00015 22.2 0.0 0.00026 21.4 0.0 1.5 1 0 0 1 1 1 1 SET domain Glyco_hydro_2_C PF02836.17 OAP55238.1 - 5.3e-109 364.0 0.0 7.2e-109 363.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.17 OAP55238.1 - 1.9e-53 181.6 0.1 3.2e-53 180.9 0.1 1.3 1 0 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.18 OAP55238.1 - 7.8e-46 156.1 0.1 2.6e-45 154.4 0.1 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain DUF4981 PF16353.5 OAP55238.1 - 6.4e-24 84.3 0.0 7.2e-21 74.5 0.0 2.7 2 0 0 2 2 2 2 Domain of unknown function(DUF4981) Glyco_hydro_2 PF00703.21 OAP55238.1 - 1.7e-13 51.2 0.0 5.1e-13 49.7 0.0 1.9 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.6 OAP55238.1 - 0.014 15.9 0.0 0.041 14.5 0.0 1.8 1 0 0 1 1 1 0 Beta-galactosidase jelly roll domain ESX-1_EspG PF14011.6 OAP55238.1 - 0.027 14.1 0.0 0.051 13.2 0.0 1.4 1 0 0 1 1 1 0 EspG family BiPBP_C PF06832.12 OAP55238.1 - 0.094 12.8 0.0 3.2 7.9 0.0 2.9 2 0 0 2 2 2 0 Penicillin-Binding Protein C-terminus Family SUN PF03856.13 OAP55239.1 - 7.9e-87 290.8 15.0 1.3e-86 290.0 15.0 1.4 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) DUF202 PF02656.15 OAP55240.1 - 2.1e-19 69.7 4.3 2.1e-19 69.7 4.3 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF202) MFS_1 PF07690.16 OAP55241.1 - 7.7e-22 77.7 30.7 7.7e-22 77.7 30.7 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily bcl-2I13 PF12201.8 OAP55241.1 - 0.11 12.4 0.3 0.19 11.7 0.3 1.4 1 0 0 1 1 1 0 Bcl2-interacting killer, BH3-domain containing FAD_binding_3 PF01494.19 OAP55242.1 - 5.5e-13 48.9 0.4 8.4e-12 45.0 0.4 2.5 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 OAP55242.1 - 0.0011 19.1 0.1 0.0031 17.7 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAP55242.1 - 0.016 14.8 2.8 0.023 14.3 0.2 2.3 2 1 1 3 3 3 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAP55242.1 - 0.21 10.8 0.2 0.36 10.0 0.1 1.5 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAP55242.1 - 0.25 10.4 3.1 0.51 9.3 0.6 2.2 1 1 0 2 2 2 0 FAD binding domain FMO-like PF00743.19 OAP55243.1 - 5.6e-28 97.7 0.0 7.3e-10 37.9 0.0 3.3 2 1 1 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OAP55243.1 - 1.5e-16 60.5 0.0 1.1e-11 44.5 0.2 3.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAP55243.1 - 2.2e-10 40.2 0.2 1.3e-07 31.1 0.0 3.0 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 OAP55243.1 - 5.4e-07 29.1 0.0 1.9e-06 27.3 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAP55243.1 - 8.7e-06 25.9 0.0 2.3e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 OAP55243.1 - 2.3e-05 24.4 0.0 0.014 15.4 0.0 3.3 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.24 OAP55243.1 - 0.00046 19.9 0.1 1 8.9 0.0 2.8 3 0 0 3 3 3 2 FAD dependent oxidoreductase Thi4 PF01946.17 OAP55243.1 - 0.01 15.1 0.1 0.022 14.0 0.0 1.5 2 0 0 2 2 2 0 Thi4 family Pyr_redox PF00070.27 OAP55243.1 - 0.023 15.2 0.9 0.72 10.5 0.0 3.0 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 OAP55243.1 - 0.048 12.9 0.0 0.43 9.8 0.0 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase PTPA PF03095.15 OAP55244.1 - 7e-110 367.2 0.0 8.3e-110 366.9 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Glyco_transf_8 PF01501.20 OAP55247.1 - 8.1e-11 41.9 0.0 7.7e-10 38.8 0.0 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mito_carr PF00153.27 OAP55248.1 - 1.8e-54 181.6 0.5 2e-18 66.1 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein RNase_PH PF01138.21 OAP55249.1 - 6.8e-10 39.6 0.0 1.6e-09 38.4 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 NAD_kinase PF01513.21 OAP55250.1 - 5.5e-79 265.4 0.0 7.5e-79 265.0 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase HEV_ORF1 PF02444.16 OAP55251.1 - 2.8 8.5 6.5 0.85 10.2 2.0 2.2 1 1 1 2 2 2 0 Hepatitis E virus ORF-2 (Putative capsid protein) DEAD PF00270.29 OAP55252.1 - 3.8e-42 144.0 0.1 6.6e-42 143.2 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAP55252.1 - 1e-33 116.0 0.1 8.4e-33 113.0 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 OAP55252.1 - 0.00026 20.8 0.0 0.00038 20.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 OAP55252.1 - 0.00038 20.5 0.0 0.00072 19.6 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 OAP55252.1 - 0.00072 19.9 0.1 0.0063 16.9 0.1 2.1 2 0 0 2 2 2 1 AAA domain Helicase_RecD PF05127.14 OAP55252.1 - 0.013 15.3 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 Helicase Flavi_DEAD PF07652.14 OAP55252.1 - 0.02 14.9 0.2 0.072 13.1 0.0 2.0 2 1 0 2 2 2 0 Flavivirus DEAD domain TniB PF05621.11 OAP55252.1 - 0.079 12.4 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein UvrD-helicase PF00580.21 OAP55252.1 - 0.11 12.1 0.1 0.16 11.5 0.1 1.3 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain AAA_22 PF13401.6 OAP55252.1 - 0.19 12.0 0.6 0.85 9.9 0.6 2.0 1 1 0 1 1 1 0 AAA domain p450 PF00067.22 OAP55253.1 - 1.3e-80 271.4 0.0 1.5e-80 271.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short_C2 PF13561.6 OAP55254.1 - 4.9e-65 219.4 0.7 5.5e-65 219.2 0.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP55254.1 - 5.8e-50 169.5 0.1 7.3e-50 169.1 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAP55254.1 - 6.7e-12 45.7 0.4 1.1e-11 45.0 0.4 1.2 1 0 0 1 1 1 1 KR domain Peripla_BP_4 PF13407.6 OAP55254.1 - 0.017 14.7 1.4 0.024 14.2 1.4 1.2 1 0 0 1 1 1 0 Periplasmic binding protein domain Ldh_1_N PF00056.23 OAP55254.1 - 0.031 14.4 0.5 0.051 13.7 0.5 1.4 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Methyltransf_14 PF08484.11 OAP55254.1 - 0.17 11.7 0.0 0.46 10.3 0.0 1.7 2 0 0 2 2 2 0 C-methyltransferase C-terminal domain adh_short_C2 PF13561.6 OAP55255.1 - 1.8e-39 135.7 0.2 2.2e-39 135.4 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP55255.1 - 1.2e-33 116.2 0.2 1.5e-33 115.9 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAP55255.1 - 3.5e-06 27.0 0.1 5.2e-06 26.5 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAP55255.1 - 0.18 11.2 0.1 0.86 9.0 0.1 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family AXE1 PF05448.12 OAP55256.1 - 9.5e-11 40.9 0.0 7.5e-07 28.1 0.0 3.0 3 0 0 3 3 3 2 Acetyl xylan esterase (AXE1) Abhydrolase_6 PF12697.7 OAP55256.1 - 4.7e-09 37.2 0.0 6e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 OAP55256.1 - 4.4e-08 33.0 0.0 8.4e-08 32.1 0.0 1.6 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.20 OAP55256.1 - 7.3e-08 32.4 0.0 2.1e-07 30.9 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OAP55256.1 - 1.3e-06 28.1 0.0 7.8e-05 22.2 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family BAAT_C PF08840.11 OAP55256.1 - 4.3e-05 23.5 0.0 0.00026 21.0 0.0 2.1 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.18 OAP55256.1 - 0.00051 19.7 0.0 0.0097 15.5 0.0 2.3 2 0 0 2 2 2 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 OAP55256.1 - 0.0091 15.3 0.0 0.13 11.5 0.0 2.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 adh_short_C2 PF13561.6 OAP55257.1 - 2.2e-58 197.6 0.1 2.5e-58 197.4 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP55257.1 - 2.6e-46 157.6 0.1 3.1e-46 157.3 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAP55257.1 - 2.2e-05 24.5 0.1 3.5e-05 23.8 0.1 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAP55257.1 - 0.0088 15.5 0.1 0.015 14.8 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 OAP55257.1 - 0.13 12.5 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Fungal_trans PF04082.18 OAP55258.1 - 6.1e-13 48.4 1.1 9.5e-13 47.8 0.6 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF5630 PF18632.1 OAP55258.1 - 0.092 12.1 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5630) adh_short_C2 PF13561.6 OAP55259.1 - 7.5e-58 195.8 0.1 8.9e-58 195.6 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP55259.1 - 2.4e-48 164.2 0.1 3.6e-48 163.6 0.1 1.3 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 OAP55259.1 - 4e-18 66.0 0.2 5.4e-18 65.5 0.2 1.2 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 OAP55259.1 - 2.1e-06 27.0 0.1 3.8e-06 26.1 0.1 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family 2-Hacid_dh_C PF02826.19 OAP55259.1 - 0.00083 18.8 0.0 0.0014 18.0 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 OAP55259.1 - 0.0034 16.7 0.0 0.0069 15.7 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Epimerase PF01370.21 OAP55259.1 - 0.019 14.4 0.1 0.038 13.5 0.1 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family HATPase_c PF02518.26 OAP55259.1 - 0.026 15.0 0.0 0.68 10.5 0.0 2.2 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Oxidored_nitro PF00148.19 OAP55259.1 - 0.028 13.1 0.0 0.08 11.7 0.0 1.7 1 1 1 2 2 2 0 Nitrogenase component 1 type Oxidoreductase TrkA_N PF02254.18 OAP55259.1 - 0.1 12.9 0.1 0.23 11.8 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain NmrA PF05368.13 OAP55259.1 - 0.1 12.1 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family ACT PF01842.25 OAP55259.1 - 0.13 12.1 0.1 19 5.1 0.0 2.9 3 0 0 3 3 3 0 ACT domain Sugar_tr PF00083.24 OAP55260.1 - 1e-89 301.5 24.9 1.2e-89 301.3 24.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP55260.1 - 8.9e-21 74.2 46.2 1.7e-13 50.2 18.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Abhydrolase_1 PF00561.20 OAP55261.1 - 1.3e-20 74.1 0.6 1.1e-19 71.2 0.6 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAP55261.1 - 9.4e-17 62.4 0.2 1.3e-16 61.9 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAP55261.1 - 1.6e-07 30.8 0.0 6e-07 29.0 0.0 1.8 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 OAP55261.1 - 0.029 13.3 0.0 0.048 12.6 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme DUF1057 PF06342.12 OAP55261.1 - 0.039 13.0 0.0 0.057 12.4 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) adh_short PF00106.25 OAP55262.1 - 6.8e-38 130.1 0.0 8.8e-38 129.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP55262.1 - 5.2e-30 104.7 0.0 7e-30 104.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP55262.1 - 1.8e-06 28.0 0.0 0.00053 19.9 0.0 2.4 2 0 0 2 2 2 2 KR domain Epimerase PF01370.21 OAP55262.1 - 0.074 12.5 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Lactamase_B_3 PF13483.6 OAP55263.1 - 3e-05 24.0 0.0 6.4e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DUF3818 PF12825.7 OAP55264.1 - 1.4e-52 178.8 4.2 2.2e-31 109.1 0.3 2.2 1 1 1 2 2 2 2 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 OAP55264.1 - 3.4e-31 107.9 0.0 8.2e-31 106.7 0.0 1.7 1 0 0 1 1 1 1 PX-associated DUF89 PF01937.19 OAP55264.1 - 0.022 13.7 0.0 0.051 12.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF89 Arrestin_C PF02752.22 OAP55265.1 - 4.3e-15 56.4 0.0 1e-14 55.1 0.0 1.7 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 OAP55265.1 - 3.9e-11 43.2 0.0 7.7e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 OAP55265.1 - 0.0086 15.8 0.0 0.017 14.9 0.0 1.5 1 0 0 1 1 1 1 Arrestin_N terminal like WD40 PF00400.32 OAP55266.1 - 1.1e-12 48.2 13.2 0.00017 22.3 0.5 5.3 5 1 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAP55266.1 - 6e-08 32.9 0.0 0.033 14.5 0.0 3.4 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OAP55266.1 - 8e-05 22.6 0.0 0.0049 16.8 0.0 2.2 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.12 OAP55266.1 - 0.00036 18.7 0.0 0.00058 18.0 0.0 1.3 1 0 0 1 1 1 1 IKI3 family PD40 PF07676.12 OAP55266.1 - 0.0055 16.6 0.0 2.1 8.4 0.0 2.8 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat WD40_like PF17005.5 OAP55266.1 - 0.024 14.0 0.0 4.4 6.5 0.1 2.4 2 0 0 2 2 2 0 WD40-like domain Cytochrom_D1 PF02239.16 OAP55266.1 - 0.04 12.4 0.0 0.091 11.3 0.0 1.6 2 0 0 2 2 2 0 Cytochrome D1 heme domain MMU163 PF17119.5 OAP55266.1 - 0.057 12.6 0.4 0.099 11.8 0.4 1.3 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis BSP_II PF05432.11 OAP55267.1 - 0.061 13.0 8.0 0.11 12.2 8.0 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Myc_N PF01056.18 OAP55267.1 - 0.084 12.8 0.9 0.091 12.6 0.9 1.1 1 0 0 1 1 1 0 Myc amino-terminal region DUF5094 PF17015.5 OAP55267.1 - 0.11 12.6 0.9 0.16 12.0 0.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5094) DUF3535 PF12054.8 OAP55267.1 - 0.12 11.6 1.0 0.28 10.4 0.1 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF3535) Cwf_Cwc_15 PF04889.12 OAP55267.1 - 0.25 11.0 7.3 0.34 10.6 7.3 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DNA_pol_phi PF04931.13 OAP55267.1 - 0.82 7.7 8.2 1.1 7.3 8.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi Sirohm_synth_M PF14824.6 OAP55267.1 - 3 7.4 4.5 41 3.7 0.1 3.1 3 0 0 3 3 3 0 Sirohaem biosynthesis protein central Endonuclease_NS PF01223.23 OAP55268.1 - 6.3e-62 209.3 0.0 7.8e-62 209.0 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Zip PF02535.22 OAP55269.1 - 1.8e-24 86.6 6.6 5.1e-16 58.8 4.9 2.1 2 0 0 2 2 2 2 ZIP Zinc transporter AAA PF00004.29 OAP55270.1 - 2e-17 63.8 0.0 3.6e-17 63.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 OAP55270.1 - 0.0041 16.9 0.0 0.0077 16.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 OAP55270.1 - 0.018 15.4 0.1 0.06 13.7 0.1 2.0 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 OAP55270.1 - 0.024 14.9 0.6 0.58 10.4 0.0 2.7 2 1 1 3 3 3 0 AAA domain AAA_5 PF07728.14 OAP55270.1 - 0.042 13.9 0.0 0.096 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_17 PF13207.6 OAP55270.1 - 0.05 14.0 0.0 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain DnaB_C PF03796.15 OAP55270.1 - 0.1 11.9 0.0 0.24 10.7 0.0 1.5 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain Zot PF05707.12 OAP55270.1 - 0.13 11.9 0.0 1.1 8.9 0.0 2.2 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) Pectate_lyase_3 PF12708.7 OAP55272.1 - 1.4e-80 270.2 17.5 2.7e-70 236.6 7.2 3.0 3 0 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 OAP55272.1 - 2e-05 24.2 0.8 0.021 14.5 0.2 2.7 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Beta_helix PF13229.6 OAP55272.1 - 0.031 14.1 4.9 0.11 12.3 4.6 2.1 1 1 1 2 2 2 0 Right handed beta helix region NosD PF05048.13 OAP55272.1 - 0.057 12.7 2.7 0.12 11.7 2.7 1.4 1 0 0 1 1 1 0 Periplasmic copper-binding protein (NosD) AMP-binding PF00501.28 OAP55274.1 - 5.4e-89 298.7 0.0 9.4e-89 297.9 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAP55274.1 - 0.003 18.5 0.5 0.0084 17.1 0.5 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Nop16 PF09420.10 OAP55274.1 - 0.1 12.6 0.0 0.29 11.1 0.0 1.7 1 0 0 1 1 1 0 Ribosome biogenesis protein Nop16 Methyltransf_16 PF10294.9 OAP55275.1 - 4.6e-15 55.8 0.6 8.2e-14 51.7 0.6 2.1 1 1 0 1 1 1 1 Lysine methyltransferase IBN_N PF03810.19 OAP55276.1 - 9.1e-16 57.6 2.2 9.3e-13 47.9 0.0 3.8 3 0 0 3 3 3 2 Importin-beta N-terminal domain Cse1 PF08506.10 OAP55276.1 - 8e-11 41.4 0.0 1.7e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 Cse1 RTP1_C1 PF10363.9 OAP55276.1 - 0.0016 18.6 0.8 0.035 14.3 0.3 2.8 2 0 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 zf-RanBP PF00641.18 OAP55277.1 - 1.8e-19 68.8 9.7 7.8e-11 41.1 1.7 2.3 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others RRM_1 PF00076.22 OAP55277.1 - 1.4e-07 31.2 0.0 2.4e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNase_T PF00929.24 OAP55277.1 - 1.9e-07 31.8 0.0 2.9e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Exonuclease zf-ribbon_3 PF13248.6 OAP55277.1 - 0.8 9.2 5.0 1.1 8.7 0.4 2.8 3 0 0 3 3 3 0 zinc-ribbon domain Oxidored_molyb PF00174.19 OAP55278.1 - 1.3e-53 181.2 0.0 1.9e-53 180.6 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 OAP55278.1 - 1.6e-18 67.1 0.1 3.8e-18 65.8 0.1 1.5 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Peptidase_M20 PF01546.28 OAP55280.1 - 1.4e-29 103.3 0.0 2.7e-29 102.4 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 OAP55280.1 - 0.00011 22.0 0.0 0.00027 20.8 0.0 1.6 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 OAP55280.1 - 0.00057 19.6 0.0 0.0013 18.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 S10_plectin PF03501.15 OAP55281.1 - 5.6e-41 138.5 0.1 7.6e-41 138.1 0.1 1.2 1 0 0 1 1 1 1 Plectin/S10 domain DUF5549 PF17703.1 OAP55281.1 - 6.5 6.4 10.0 12 5.4 10.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5549) Ribosomal_S8e PF01201.22 OAP55282.1 - 1.3e-54 184.1 1.8 1.4e-54 183.9 1.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S8e Ribosomal_60s PF00428.19 OAP55282.1 - 0.022 15.3 1.5 0.037 14.6 1.5 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein ADH_N PF08240.12 OAP55284.1 - 2.7e-35 120.5 0.9 2.7e-35 120.5 0.9 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAP55284.1 - 3e-15 56.3 0.0 5e-15 55.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 OAP55284.1 - 1.1e-11 44.7 0.0 1.6e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 OAP55284.1 - 6.2e-07 30.5 0.0 1.1e-06 29.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FAD_binding_3 PF01494.19 OAP55284.1 - 0.014 14.6 0.1 0.024 13.9 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain HECT PF00632.25 OAP55285.1 - 7.8e-73 245.6 0.0 1.1e-72 245.1 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) ITAM_Cys-rich PF10538.9 OAP55285.1 - 3.9 7.3 5.3 1 9.2 1.4 2.0 2 0 0 2 2 2 0 Immunoreceptor tyrosine-based activation motif GMC_oxred_N PF00732.19 OAP55286.1 - 3.2e-47 161.3 0.0 4.4e-47 160.9 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAP55286.1 - 5.8e-33 114.4 0.0 1.2e-32 113.4 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 OAP55286.1 - 4e-06 26.1 0.1 6.5e-06 25.4 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.14 OAP55286.1 - 0.00079 18.2 0.2 0.027 13.2 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.24 OAP55286.1 - 0.0013 18.4 0.8 0.0076 15.9 0.8 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OAP55286.1 - 0.0018 17.4 0.3 0.099 11.7 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 OAP55286.1 - 0.0047 17.1 1.1 0.014 15.6 0.2 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 OAP55286.1 - 0.0056 16.7 0.2 0.18 11.8 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 OAP55286.1 - 0.0065 15.7 0.1 0.53 9.5 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAP55286.1 - 0.015 14.6 0.0 2 7.6 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OAP55286.1 - 0.057 12.5 0.2 1.8 7.6 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A MMR_HSR1 PF01926.23 OAP55287.1 - 1.5e-05 25.1 0.0 0.22 11.6 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase ADH_zinc_N_2 PF13602.6 OAP55288.1 - 3.6e-18 66.9 0.0 5.9e-18 66.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 OAP55288.1 - 1.7e-12 47.4 0.0 3.2e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAP55288.1 - 6.4e-10 38.9 0.1 6.4e-08 32.5 0.0 2.5 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 OAP55288.1 - 0.057 13.3 0.0 0.2 11.6 0.0 1.8 2 0 0 2 2 2 0 N-terminal domain of oxidoreductase Uds1 PF15456.6 OAP55289.1 - 0.0061 16.7 1.8 0.0078 16.4 1.8 1.2 1 0 0 1 1 1 1 Up-regulated During Septation Herpes_UL6 PF01763.16 OAP55289.1 - 0.027 13.0 0.2 0.027 13.0 0.2 1.0 1 0 0 1 1 1 0 Herpesvirus UL6 like SlyX PF04102.12 OAP55289.1 - 0.039 14.6 2.6 0.07 13.8 2.6 1.4 1 0 0 1 1 1 0 SlyX Selenoprotein_S PF06936.11 OAP55289.1 - 0.064 13.1 2.4 0.081 12.7 2.4 1.1 1 0 0 1 1 1 0 Selenoprotein S (SelS) Bromodomain PF00439.25 OAP55290.1 - 1.4e-07 31.5 0.0 5.5e-06 26.4 0.0 2.4 2 0 0 2 2 2 2 Bromodomain PI-PLC-X PF00388.19 OAP55291.1 - 3.1e-60 202.0 0.0 5.2e-60 201.2 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 OAP55291.1 - 9.4e-41 138.8 0.2 2.4e-40 137.5 0.2 1.8 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain PH_12 PF16457.5 OAP55291.1 - 0.00074 20.1 0.1 0.0022 18.5 0.1 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain CATSPERB PF15149.6 OAP55291.1 - 0.01 14.4 0.1 0.02 13.5 0.1 1.3 1 0 0 1 1 1 0 Cation channel sperm-associated protein subunit beta protein family EF-hand_7 PF13499.6 OAP55291.1 - 0.015 15.7 1.2 0.09 13.2 1.5 2.0 1 1 1 2 2 2 0 EF-hand domain pair EF-hand_like PF09279.11 OAP55291.1 - 0.041 14.4 0.0 0.094 13.2 0.0 1.6 1 0 0 1 1 1 0 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_6 PF13405.6 OAP55291.1 - 0.12 12.4 0.2 0.73 9.9 0.1 2.3 1 1 1 2 2 2 0 EF-hand domain DUF3431 PF11913.8 OAP55292.1 - 7.4e-67 225.3 0.0 9e-67 225.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Mcp5_PH PF12814.7 OAP55294.1 - 0.092 12.9 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology LRR_4 PF12799.7 OAP55295.1 - 0.054 13.9 8.8 0.82 10.2 0.3 5.4 6 0 0 6 6 6 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 OAP55295.1 - 8 6.8 17.5 18 5.7 0.0 6.8 9 0 0 9 9 9 0 Leucine Rich repeat Ribosomal_L5e PF17144.4 OAP55296.1 - 6.4e-81 270.1 0.2 6.4e-81 270.1 0.2 1.7 2 0 0 2 2 2 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 OAP55296.1 - 1.6e-34 118.7 10.2 1.6e-34 118.7 10.2 2.0 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region MscS_porin PF12795.7 OAP55297.1 - 0.056 13.0 5.9 0.11 12.1 5.9 1.5 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Spc7 PF08317.11 OAP55297.1 - 0.066 12.1 3.3 0.12 11.3 3.3 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein adh_short PF00106.25 OAP55299.1 - 4.2e-17 62.2 0.0 2.4e-16 59.8 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP55299.1 - 9.8e-13 48.2 0.0 9.8e-12 44.9 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP55299.1 - 9.1e-07 29.0 0.0 1.3e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAP55299.1 - 1.9e-06 27.6 0.0 2.4e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 OAP55299.1 - 1e-05 25.5 0.0 1.5e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Glyco_transf_4 PF13439.6 OAP55299.1 - 0.011 15.8 0.0 0.017 15.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase Family 4 p450 PF00067.22 OAP55300.1 - 9e-45 153.3 0.0 1.2e-44 152.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Amidase PF01425.21 OAP55301.1 - 4.4e-68 230.3 0.1 8.5e-67 226.0 0.1 2.0 1 1 0 1 1 1 1 Amidase Fungal_trans_2 PF11951.8 OAP55302.1 - 3.9e-13 49.0 0.6 1.5e-10 40.4 0.1 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain MFS_1 PF07690.16 OAP55304.1 - 1.3e-41 142.7 23.3 1.6e-41 142.4 23.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily ATG22 PF11700.8 OAP55304.1 - 2.6e-06 26.4 6.4 2.6e-06 26.4 6.4 1.7 2 0 0 2 2 2 1 Vacuole effluxer Atg22 like SieB PF14163.6 OAP55304.1 - 0.041 13.4 2.3 0.6 9.6 0.1 2.8 2 0 0 2 2 2 0 Super-infection exclusion protein B Saf_2TM PF18303.1 OAP55304.1 - 0.27 10.8 5.9 3.3 7.3 0.4 3.9 4 0 0 4 4 4 0 SAVED-fused 2TM effector domain PrgI PF12666.7 OAP55304.1 - 2.4 8.9 9.2 2.4 8.9 0.4 3.6 3 1 0 3 3 3 0 PrgI family protein MFS_1 PF07690.16 OAP55305.1 - 4.9e-41 140.8 32.0 1.6e-40 139.2 32.8 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAP55305.1 - 5.9e-13 48.5 27.0 2.3e-12 46.5 27.0 2.7 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 OAP55305.1 - 5.5e-07 28.4 1.0 5.5e-07 28.4 1.0 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) ApbA_C PF08546.11 OAP55306.1 - 7.8e-28 97.2 0.1 1.4e-27 96.3 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 OAP55306.1 - 2.2e-26 92.3 0.0 3e-26 91.9 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.6 OAP55306.1 - 0.035 14.6 0.0 0.092 13.2 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding Sacchrp_dh_NADP PF03435.18 OAP55306.1 - 0.036 14.3 0.0 1.4 9.2 0.0 2.3 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain GFO_IDH_MocA PF01408.22 OAP55306.1 - 0.095 13.5 0.0 0.2 12.5 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Abhydrolase_6 PF12697.7 OAP55307.1 - 2.8e-19 70.6 1.6 3.3e-19 70.4 1.6 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 OAP55307.1 - 0.0016 18.6 0.1 0.0031 17.7 0.0 1.5 2 0 0 2 2 2 1 Thioesterase domain HMGL-like PF00682.19 OAP55308.1 - 7.7e-79 265.0 0.8 1.1e-78 264.4 0.8 1.2 1 0 0 1 1 1 1 HMGL-like Pyridoxal_deC PF00282.19 OAP55309.1 - 9.9e-18 64.0 0.0 1.6e-17 63.3 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 OAP55309.1 - 1.3e-06 27.6 0.0 2.5e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 OAP55309.1 - 0.00051 19.5 0.1 0.00081 18.8 0.1 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Clr5 PF14420.6 OAP55310.1 - 2.6e-07 30.8 0.0 5.7e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Clr5 domain TPR_12 PF13424.6 OAP55310.1 - 0.00022 21.4 3.5 0.00041 20.6 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 OAP55310.1 - 0.0079 16.8 3.9 0.0091 16.6 1.6 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat Serglycin PF04360.12 OAP55310.1 - 0.016 15.1 0.7 0.016 15.1 0.7 2.1 2 0 0 2 2 2 0 Serglycin DUF4032 PF13224.6 OAP55310.1 - 0.046 13.6 0.1 0.15 11.9 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4032) Urocanase PF01175.18 OAP55310.1 - 0.083 12.5 0.0 0.21 11.2 0.0 1.6 2 0 0 2 2 2 0 Urocanase Rossmann-like domain TPR_2 PF07719.17 OAP55310.1 - 0.34 11.1 2.4 3.3 8.0 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat NTP_transferase PF00483.23 OAP55311.1 - 2.2e-52 178.1 0.0 4.2e-52 177.2 0.0 1.4 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.24 OAP55311.1 - 3.9e-14 51.7 6.3 1e-10 40.9 1.1 3.7 2 1 1 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 OAP55311.1 - 2.3e-10 41.1 0.0 2.9e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 OAP55311.1 - 1.5e-05 24.6 11.4 2e-05 24.2 1.5 3.3 3 1 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase IspD PF01128.19 OAP55311.1 - 0.0092 15.7 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase DUF166 PF02593.14 OAP55311.1 - 0.051 13.1 0.1 0.93 9.0 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function CTP_transf_3 PF02348.19 OAP55311.1 - 0.098 12.6 0.0 0.22 11.4 0.0 1.5 2 0 0 2 2 2 0 Cytidylyltransferase DUF4954 PF16314.5 OAP55311.1 - 0.17 10.0 0.1 1 7.4 0.0 2.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4954) SRP40_C PF05022.12 OAP55313.1 - 3.6e-18 66.2 3.2 1.7e-17 64.0 3.2 2.2 1 0 0 1 1 1 1 SRP40, C-terminal domain LisH PF08513.11 OAP55313.1 - 0.00049 19.9 0.0 0.00088 19.2 0.0 1.4 1 0 0 1 1 1 1 LisH Glycos_transf_1 PF00534.20 OAP55313.1 - 0.017 14.6 0.0 0.7 9.4 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferases group 1 Nmad5 PF18757.1 OAP55313.1 - 6.3 6.9 8.5 0.56 10.4 0.5 2.3 1 1 1 2 2 2 0 Nucleotide modification associated domain 5 p450 PF00067.22 OAP55314.1 - 2.5e-60 204.5 0.0 3.4e-60 204.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fasciclin PF02469.22 OAP55316.1 - 1.2e-21 77.3 4.5 2.4e-18 66.6 0.2 2.6 2 1 0 2 2 2 2 Fasciclin domain DASH_Ask1 PF08655.10 OAP55317.1 - 3e-30 103.9 0.2 5.1e-30 103.2 0.2 1.4 1 0 0 1 1 1 1 DASH complex subunit Ask1 Chitin_synth_2 PF03142.15 OAP55319.1 - 6.5e-26 91.0 2.7 3.6e-23 82.0 1.9 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 OAP55319.1 - 6.6e-17 62.1 5.7 6.6e-17 62.1 5.7 2.2 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 OAP55319.1 - 3.5e-10 40.2 0.0 6.8e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 OAP55319.1 - 0.037 13.8 0.1 5.3 6.8 0.0 2.5 2 0 0 2 2 2 0 Glycosyl transferase family 2 MitoNEET_N PF10660.9 OAP55319.1 - 0.14 12.2 1.2 0.36 10.9 1.2 1.7 1 0 0 1 1 1 0 Iron-containing outer mitochondrial membrane protein N-terminus HSP70 PF00012.20 OAP55320.1 - 7.9e-163 542.8 2.3 7.9e-163 542.8 2.3 1.9 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 OAP55320.1 - 2e-09 36.7 0.0 5.3e-09 35.3 0.0 1.6 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 OAP55320.1 - 0.0024 18.2 2.9 0.34 11.3 0.0 3.4 3 2 0 3 3 3 2 Cell division protein FtsA DUF4288 PF14119.6 OAP55320.1 - 0.5 10.8 3.6 1.4 9.3 3.6 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4288) DUF45 PF01863.17 OAP55320.1 - 4.2 7.4 6.8 7 6.6 5.5 2.0 2 0 0 2 2 2 0 Protein of unknown function DUF45 Thiolase_N PF00108.23 OAP55321.1 - 2.4e-64 217.2 0.1 3.2e-64 216.8 0.1 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 OAP55321.1 - 4.3e-41 139.4 0.4 8.8e-41 138.4 0.4 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 OAP55321.1 - 0.0011 18.6 1.7 0.0024 17.5 0.8 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain PAC2 PF09754.9 OAP55322.1 - 0.015 15.3 0.0 0.026 14.6 0.0 1.4 1 0 0 1 1 1 0 PAC2 family Goodbye PF17109.5 OAP55322.1 - 0.019 15.4 1.0 0.048 14.1 0.2 2.1 2 0 0 2 2 2 0 fungal STAND N-terminal Goodbye domain DUF1512 PF07431.12 OAP55322.1 - 0.49 9.3 2.8 2.6 7.0 0.2 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1512) AAA PF00004.29 OAP55323.1 - 2e-17 63.9 0.0 1.9e-16 60.7 0.0 2.5 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 OAP55323.1 - 0.003 17.5 0.6 0.044 13.8 0.1 2.7 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 OAP55323.1 - 0.0051 17.1 0.8 0.083 13.2 0.2 2.6 1 1 1 2 2 2 1 AAA domain Sigma54_activat PF00158.26 OAP55323.1 - 0.0095 15.7 0.1 0.021 14.5 0.0 1.6 1 1 1 2 2 2 1 Sigma-54 interaction domain AAA_16 PF13191.6 OAP55323.1 - 0.0095 16.3 0.1 0.053 13.9 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 OAP55323.1 - 0.023 15.0 0.0 0.046 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 OAP55323.1 - 0.027 14.2 0.0 0.053 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF3570 PF12094.8 OAP55323.1 - 0.13 11.0 0.0 0.21 10.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3570) Torsin PF06309.11 OAP55323.1 - 0.14 12.3 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 Torsin ATPase PF06745.13 OAP55323.1 - 0.18 11.1 0.3 0.39 10.0 0.3 1.5 1 0 0 1 1 1 0 KaiC AAA_28 PF13521.6 OAP55323.1 - 0.51 10.6 6.5 0.12 12.7 0.5 3.0 3 1 0 3 3 3 0 AAA domain adh_short_C2 PF13561.6 OAP55324.1 - 3.1e-61 206.9 1.6 3.6e-61 206.7 1.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP55324.1 - 4.6e-52 176.3 0.8 5.7e-52 176.0 0.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAP55324.1 - 1.7e-12 47.6 0.5 2.3e-12 47.2 0.5 1.1 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 OAP55324.1 - 7.9e-05 22.6 0.1 0.00019 21.4 0.1 1.6 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_25 PF13649.6 OAP55324.1 - 0.0028 18.3 0.1 0.0063 17.2 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Semialdhyde_dh PF01118.24 OAP55324.1 - 0.0029 18.0 0.1 0.0061 17.0 0.1 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 OAP55324.1 - 0.0038 16.4 0.2 0.0046 16.1 0.2 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein UDPG_MGDP_dh_N PF03721.14 OAP55324.1 - 0.0048 16.5 0.0 0.011 15.3 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ADH_zinc_N PF00107.26 OAP55324.1 - 0.01 15.8 0.2 0.02 14.9 0.2 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Epimerase PF01370.21 OAP55324.1 - 0.017 14.6 1.0 0.08 12.4 1.0 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NUDIX_2 PF13869.6 OAP55324.1 - 0.028 14.0 0.0 0.037 13.6 0.0 1.2 1 0 0 1 1 1 0 Nucleotide hydrolase Methyltransf_11 PF08241.12 OAP55324.1 - 0.094 13.4 0.0 0.17 12.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Myb_DNA-binding PF00249.31 OAP55325.1 - 1.5e-31 108.3 8.9 3.4e-12 46.3 0.3 3.6 3 1 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OAP55325.1 - 5.5e-28 97.0 1.9 4.5e-12 46.0 0.2 3.7 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OAP55325.1 - 3e-07 30.2 0.0 0.00024 20.9 0.0 2.7 2 0 0 2 2 2 2 Myb DNA-binding like Rap1_C PF11626.8 OAP55325.1 - 0.35 11.0 1.9 19 5.5 0.0 3.3 2 1 1 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain ketoacyl-synt PF00109.26 OAP55326.1 - 7.2e-80 268.2 0.0 1.5e-79 267.2 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain SAT PF16073.5 OAP55326.1 - 2.9e-71 240.0 0.0 9.8e-69 231.7 0.0 2.6 2 0 0 2 2 2 2 Starter unit:ACP transacylase in aflatoxin biosynthesis Acyl_transf_1 PF00698.21 OAP55326.1 - 3.8e-45 154.8 0.0 6.8e-45 153.9 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 OAP55326.1 - 5.3e-36 123.2 0.1 2.2e-35 121.2 0.1 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.25 OAP55326.1 - 6.8e-25 87.2 4.5 1.3e-11 44.6 0.1 2.9 2 0 0 2 2 2 2 Phosphopantetheine attachment site Thioesterase PF00975.20 OAP55326.1 - 4.8e-24 85.7 1.7 2.1e-22 80.4 0.0 3.1 3 0 0 3 3 3 1 Thioesterase domain PS-DH PF14765.6 OAP55326.1 - 1.4e-17 63.8 0.0 3e-17 62.8 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Thiolase_N PF00108.23 OAP55326.1 - 0.0001 21.7 0.0 0.00023 20.6 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Abhydrolase_6 PF12697.7 OAP55326.1 - 0.00014 22.6 0.3 0.011 16.4 0.1 2.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAP55326.1 - 0.03 14.0 0.0 10 5.7 0.0 3.1 3 0 0 3 3 3 0 alpha/beta hydrolase fold Telomere_Sde2_2 PF13297.6 OAP55326.1 - 0.14 11.9 2.7 0.65 9.7 0.1 3.1 4 0 0 4 4 3 0 Telomere stability C-terminal REC104 PF17378.2 OAP55326.1 - 0.15 11.8 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 Meiotic recombination protein REC104 ACP_syn_III PF08545.10 OAP55326.1 - 0.8 9.6 2.6 33 4.4 2.3 3.1 2 1 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III FAD_binding_3 PF01494.19 OAP55327.1 - 1.4e-19 70.6 0.0 2.6e-19 69.7 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.24 OAP55327.1 - 1.8e-05 24.3 0.2 0.067 12.5 0.0 2.4 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OAP55327.1 - 4.4e-05 23.6 0.7 0.00016 21.8 0.7 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 OAP55327.1 - 6.8e-05 22.1 0.3 0.00047 19.3 0.3 2.0 1 1 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 OAP55327.1 - 9.8e-05 21.7 0.0 0.0087 15.3 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAP55327.1 - 0.00029 20.5 3.3 0.002 17.8 1.4 2.3 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OAP55327.1 - 0.00046 19.4 0.0 0.00067 18.8 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain SE PF08491.10 OAP55327.1 - 0.0028 16.8 0.0 0.0063 15.6 0.0 1.5 2 0 0 2 2 2 1 Squalene epoxidase NAD_binding_9 PF13454.6 OAP55327.1 - 0.0095 15.9 0.5 0.79 9.7 0.5 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 OAP55327.1 - 0.016 15.8 0.1 0.07 13.7 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase WHH PF14414.6 OAP55327.1 - 0.13 12.2 1.0 0.22 11.4 0.1 1.8 2 0 0 2 2 2 0 A nuclease of the HNH/ENDO VII superfamily with conserved WHH HI0933_like PF03486.14 OAP55327.1 - 0.15 10.7 0.3 0.59 8.8 0.3 1.9 1 1 0 1 1 1 0 HI0933-like protein FAD_binding_4 PF01565.23 OAP55328.1 - 4.9e-17 62.0 0.8 1.3e-16 60.5 0.8 1.8 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 OAP55328.1 - 1.5e-11 44.2 0.4 3.6e-11 43.0 0.4 1.7 1 0 0 1 1 1 1 Berberine and berberine like Scytalone_dh PF02982.14 OAP55329.1 - 3e-48 163.6 0.5 3.5e-48 163.4 0.5 1.0 1 0 0 1 1 1 1 Scytalone dehydratase adh_short_C2 PF13561.6 OAP55330.1 - 8.3e-53 179.3 0.2 1.4e-52 178.6 0.2 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP55330.1 - 2.3e-51 174.0 0.7 2.8e-51 173.8 0.7 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAP55330.1 - 1.5e-20 73.9 0.3 2.1e-20 73.4 0.3 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAP55330.1 - 0.0078 15.7 0.1 0.016 14.7 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Methyltransf_23 PF13489.6 OAP55330.1 - 0.068 13.0 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain THF_DHG_CYH_C PF02882.19 OAP55330.1 - 0.1 11.9 0.4 1.8 7.9 0.1 2.1 1 1 1 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF1776 PF08643.10 OAP55330.1 - 0.11 11.9 0.0 0.24 10.7 0.0 1.6 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) NmrA PF05368.13 OAP55331.1 - 2.5e-59 200.7 0.1 3.2e-59 200.3 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAP55331.1 - 1.4e-18 67.5 0.0 2.1e-18 66.9 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 OAP55331.1 - 3e-07 29.7 0.0 5.7e-07 28.8 0.0 1.4 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Sacchrp_dh_NADP PF03435.18 OAP55331.1 - 0.017 15.4 0.1 0.025 14.8 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Ank_2 PF12796.7 OAP55332.1 - 2.2e-72 239.7 0.0 5.4e-14 52.5 0.0 7.0 1 1 6 7 7 7 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAP55332.1 - 2e-64 213.2 0.0 7.2e-11 42.4 0.0 7.7 3 1 6 9 9 9 8 Ankyrin repeats (many copies) Ank PF00023.30 OAP55332.1 - 3.5e-53 175.8 0.0 7.3e-06 26.2 0.0 9.8 9 0 0 9 9 9 9 Ankyrin repeat Ank_3 PF13606.6 OAP55332.1 - 8.5e-50 160.9 0.0 0.0013 19.0 0.0 10.7 11 0 0 11 11 10 9 Ankyrin repeat Ank_5 PF13857.6 OAP55332.1 - 4.4e-43 144.8 0.0 4.1e-09 36.5 0.0 9.0 2 1 6 9 9 9 8 Ankyrin repeats (many copies) HET PF06985.11 OAP55332.1 - 3.4e-11 43.7 5.3 9.9e-09 35.7 0.5 2.8 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) AAA_16 PF13191.6 OAP55332.1 - 2.2e-05 24.9 0.0 0.00041 20.8 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 OAP55332.1 - 0.00043 20.2 0.0 0.001 19.0 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 OAP55332.1 - 0.00098 19.4 0.0 0.0036 17.6 0.0 2.0 1 0 0 1 1 1 1 AAA domain Myelin-PO_C PF10570.9 OAP55332.1 - 0.076 13.4 0.0 28 5.2 0.0 3.8 2 1 1 3 3 3 0 Myelin-PO cytoplasmic C-term p65 binding region VCH_CASS14 PF18315.1 OAP55332.1 - 0.11 12.6 0.9 79 3.4 0.0 4.3 1 1 2 4 4 4 0 Integron cassette protein VCH_CASS1 chain YppF PF14178.6 OAP55332.1 - 0.19 11.6 0.3 20 5.2 0.0 3.9 4 0 0 4 4 4 0 YppF-like protein Zn_clus PF00172.18 OAP55334.1 - 5e-10 39.3 9.6 1.1e-09 38.2 9.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.25 OAP55335.1 - 1.6e-37 128.9 0.0 2e-37 128.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP55335.1 - 7.4e-34 117.3 0.0 1.4e-33 116.4 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP55335.1 - 1.8e-09 37.8 0.0 2.7e-09 37.2 0.0 1.1 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 OAP55335.1 - 0.095 12.0 0.1 0.16 11.3 0.1 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.21 OAP55335.1 - 0.18 11.2 0.0 0.85 9.0 0.0 1.9 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Arylsulfotran_2 PF14269.6 OAP55336.1 - 1.2e-40 139.8 0.2 1.7e-40 139.3 0.2 1.1 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 OAP55336.1 - 1.3e-11 44.1 1.5 5.6e-10 38.7 1.5 2.3 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) DctP PF03480.13 OAP55336.1 - 0.092 12.1 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein, family 7 DAP_B PF07930.12 OAP55338.1 - 2.6e-67 226.3 0.0 3.5e-67 225.9 0.0 1.2 1 0 0 1 1 1 1 D-aminopeptidase, domain B Beta-lactamase PF00144.24 OAP55338.1 - 4.4e-36 124.8 0.0 6.5e-36 124.2 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase La PF05383.17 OAP55340.1 - 2.3e-20 72.4 0.0 4e-20 71.6 0.0 1.4 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 OAP55340.1 - 4.1e-08 32.9 0.1 1.2e-07 31.4 0.1 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cyclin_N PF00134.23 OAP55341.1 - 8.2e-11 41.7 0.1 4.8e-10 39.3 0.0 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain Exo70 PF03081.15 OAP55342.1 - 7.8e-78 262.1 0.0 1.9e-76 257.6 0.0 2.0 2 0 0 2 2 2 2 Exo70 exocyst complex subunit Herpes_BTRF1 PF04682.12 OAP55342.1 - 0.01 15.2 0.1 0.44 9.8 0.0 2.5 2 0 0 2 2 2 2 Herpesvirus BTRF1 protein conserved region PLA2_B PF01735.18 OAP55343.1 - 7.2e-25 87.3 0.0 2.5e-24 85.6 0.0 1.8 1 1 0 1 1 1 1 Lysophospholipase catalytic domain Phosphodiest PF01663.22 OAP55344.1 - 4.2e-89 299.6 0.3 5.5e-89 299.2 0.3 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF5427 PF10310.9 OAP55344.1 - 0.74 8.7 15.6 2.2 7.1 1.9 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5427) DUF755 PF05501.11 OAP55344.1 - 1.4 9.2 6.3 2.8 8.2 6.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF755) AATase PF07247.12 OAP55345.1 - 2.3e-15 56.1 0.0 2.5e-14 52.7 0.0 2.1 1 1 0 1 1 1 1 Alcohol acetyltransferase Abhydrolase_3 PF07859.13 OAP55346.1 - 1.8e-48 165.2 0.0 2.5e-48 164.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 OAP55346.1 - 7.8e-10 38.2 0.5 3e-09 36.3 0.5 1.7 1 1 0 1 1 1 1 Carboxylesterase family RIBIOP_C PF04950.12 OAP55347.1 - 2.7e-100 335.5 0.0 5.2e-100 334.6 0.0 1.5 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 OAP55347.1 - 2.7e-21 75.5 0.0 6.3e-21 74.3 0.0 1.7 1 0 0 1 1 1 1 AARP2CN (NUC121) domain Ank_2 PF12796.7 OAP55348.1 - 1.7e-65 217.6 0.0 1.9e-10 41.2 0.0 10.6 4 2 5 11 11 11 11 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAP55348.1 - 2.2e-58 193.9 0.1 2.4e-07 31.2 0.0 13.1 11 3 2 13 13 13 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAP55348.1 - 1e-51 166.8 9.9 3.5e-06 26.9 0.0 18.0 18 0 0 18 18 18 10 Ankyrin repeat Ank PF00023.30 OAP55348.1 - 3.5e-35 118.9 16.6 5.8e-06 26.5 0.1 16.9 18 1 0 18 18 18 5 Ankyrin repeat Ank_5 PF13857.6 OAP55348.1 - 2.9e-26 91.2 6.8 0.0022 18.3 0.0 13.4 12 1 3 15 15 15 6 Ankyrin repeats (many copies) Clr5 PF14420.6 OAP55348.1 - 1.2e-16 60.6 0.8 2.2e-16 59.8 0.8 1.5 1 0 0 1 1 1 1 Clr5 domain 2-Hacid_dh_C PF02826.19 OAP55348.1 - 0.1 12.0 0.0 1.1 8.6 0.0 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Bromodomain PF00439.25 OAP55350.1 - 2.2e-42 143.0 0.8 5.7e-20 71.2 0.2 2.4 2 0 0 2 2 2 2 Bromodomain BET PF17035.5 OAP55350.1 - 6.1e-17 61.5 0.1 6.1e-17 61.5 0.1 2.1 2 0 0 2 2 2 1 Bromodomain extra-terminal - transcription regulation CDC45 PF02724.14 OAP55350.1 - 0.081 11.2 15.3 0.13 10.5 15.3 1.2 1 0 0 1 1 1 0 CDC45-like protein T2SSM PF04612.12 OAP55350.1 - 0.092 12.8 1.2 19 5.3 1.1 2.9 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein M Allexi_40kDa PF05549.11 OAP55350.1 - 0.16 11.5 3.3 0.49 9.9 3.3 1.8 1 0 0 1 1 1 0 Allexivirus 40kDa protein S-antigen PF05756.11 OAP55350.1 - 0.28 11.6 1.2 0.77 10.2 1.2 1.7 1 0 0 1 1 1 0 S-antigen protein DUF3573 PF12097.8 OAP55350.1 - 1.4 7.7 4.2 2.4 6.9 4.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) RRN3 PF05327.11 OAP55350.1 - 3.8 5.9 8.6 6.5 5.2 8.6 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 V_ATPase_I PF01496.19 OAP55350.1 - 7.1 4.4 9.0 10 3.9 9.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Utp12 PF04003.12 OAP55351.1 - 5.2e-22 78.2 0.6 1.3e-21 76.9 0.1 1.9 2 0 0 2 2 2 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 OAP55351.1 - 0.026 14.8 0.0 3.5 8.0 0.0 3.7 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OAP55352.1 - 4.1e-07 30.6 0.2 0.00027 21.7 0.0 2.8 2 0 0 2 2 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAP55352.1 - 0.039 14.2 0.0 0.38 11.1 0.0 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain PPTA PF01239.22 OAP55353.1 - 8.5e-37 123.8 18.0 6.3e-08 32.1 2.0 5.7 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat RabGAP-TBC PF00566.18 OAP55354.1 - 1.5e-47 162.1 0.2 2.7e-46 157.9 0.1 2.6 2 0 0 2 2 2 1 Rab-GTPase-TBC domain AviRa PF11599.8 OAP55354.1 - 0.18 11.3 4.9 0.33 10.4 4.9 1.4 1 0 0 1 1 1 0 RRNA methyltransferase AviRa Tropomyosin_1 PF12718.7 OAP55354.1 - 0.22 11.7 26.8 0.56 10.4 9.3 3.0 1 1 1 2 2 2 0 Tropomyosin like Cnn_1N PF07989.11 OAP55354.1 - 0.35 11.1 24.7 0.42 10.8 6.3 3.9 2 2 1 3 3 3 0 Centrosomin N-terminal motif 1 HALZ PF02183.18 OAP55354.1 - 0.37 11.0 6.8 4.5 7.6 0.6 3.0 2 0 0 2 2 2 0 Homeobox associated leucine zipper YabA PF06156.13 OAP55354.1 - 0.5 11.0 20.6 3.8 8.2 6.3 3.6 2 1 1 3 3 3 0 Initiation control protein YabA DivIC PF04977.15 OAP55354.1 - 0.65 9.8 20.4 1 9.2 4.2 3.7 1 1 1 3 3 3 0 Septum formation initiator Cep57_MT_bd PF06657.13 OAP55354.1 - 2.4 8.6 12.6 6.4 7.3 2.9 3.4 2 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Fez1 PF06818.15 OAP55354.1 - 5.2 7.5 27.7 2.8 8.4 24.3 2.1 2 0 0 2 2 2 0 Fez1 AMP-binding PF00501.28 OAP55355.1 - 9.8e-70 235.3 0.0 1.2e-69 235.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAP55355.1 - 3.4e-06 27.9 0.0 6.8e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Methyltransf_30 PF05430.11 OAP55356.1 - 0.0052 16.7 0.0 0.084 12.8 0.0 2.3 2 0 0 2 2 2 1 S-adenosyl-L-methionine-dependent methyltransferase Ctf8 PF09696.10 OAP55357.1 - 3.7e-40 137.6 0.1 5.2e-40 137.1 0.1 1.2 1 0 0 1 1 1 1 Ctf8 Glyco_hydro_32N PF00251.20 OAP55358.1 - 1.3e-25 90.7 0.0 1.9e-25 90.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 OAP55358.1 - 2.9e-22 79.4 0.0 5.3e-22 78.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal DUF4975 PF16346.5 OAP55358.1 - 0.0028 17.7 0.0 0.0064 16.6 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4975) ATP-synt_ab PF00006.25 OAP55359.1 - 2.9e-67 226.4 0.0 3.8e-67 226.1 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 OAP55359.1 - 8.3e-14 51.9 0.3 1.5e-13 51.1 0.3 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain MFS_1 PF07690.16 OAP55360.1 - 8.8e-16 57.8 17.1 6.9e-15 54.8 17.0 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAP55360.1 - 1.8e-05 23.8 8.5 3.8e-05 22.7 7.5 2.1 1 1 1 2 2 2 1 Sugar (and other) transporter Abhydrolase_1 PF00561.20 OAP55361.1 - 1.7e-16 60.7 0.1 4.6e-16 59.2 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAP55361.1 - 2.8e-13 51.0 3.9 4.7e-13 50.2 3.9 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAP55361.1 - 1.2e-10 41.1 0.0 2.1e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 OAP55361.1 - 5.1e-05 22.1 0.0 7.3e-05 21.6 0.0 1.3 1 0 0 1 1 1 1 Ndr family Thioesterase PF00975.20 OAP55361.1 - 0.0049 17.0 0.3 0.014 15.5 0.3 1.8 1 1 0 1 1 1 1 Thioesterase domain Dicty_CAR PF05462.11 OAP55362.1 - 9.5e-11 41.4 7.1 9.5e-11 41.4 7.1 1.9 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor Git3 PF11710.8 OAP55362.1 - 1.2e-07 31.8 7.8 1.9e-07 31.1 7.8 1.3 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.21 OAP55362.1 - 5.3e-07 29.2 1.2 6.9e-07 28.8 1.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OAP55362.1 - 0.0045 16.4 1.8 0.0092 15.4 0.6 1.9 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx Frizzled PF01534.17 OAP55362.1 - 3.6 6.6 18.1 0.29 10.1 8.1 2.4 2 1 1 3 3 3 0 Frizzled/Smoothened family membrane region PPI_Ypi1 PF07491.11 OAP55363.1 - 7.7e-25 86.5 6.3 3.8e-24 84.3 6.3 2.1 1 1 0 1 1 1 1 Protein phosphatase inhibitor CDC45 PF02724.14 OAP55363.1 - 0.97 7.7 6.9 1.1 7.5 6.9 1.1 1 0 0 1 1 1 0 CDC45-like protein SelP_N PF04592.14 OAP55363.1 - 1.4 8.3 8.8 2 7.8 8.8 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region CCDC106 PF15794.5 OAP55363.1 - 5.7 6.6 5.6 2.7 7.6 3.3 1.6 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 106 CRM1_C PF08767.11 OAP55364.1 - 4.9e-136 453.1 3.6 4.9e-136 453.1 3.6 3.1 3 0 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.12 OAP55364.1 - 2.6e-38 131.4 12.6 3e-38 131.2 7.6 3.6 3 1 0 3 3 3 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 OAP55364.1 - 4.2e-33 112.8 3.8 7.4e-33 112.0 2.6 2.2 2 0 0 2 2 2 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 OAP55364.1 - 1e-29 102.3 1.2 1e-29 102.3 1.2 2.6 3 0 0 3 3 3 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 OAP55364.1 - 5.8e-20 70.5 3.3 1.3e-19 69.4 3.3 1.7 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 OAP55364.1 - 3.5e-10 39.7 0.0 1.4e-09 37.7 0.0 2.2 1 0 0 1 1 1 1 Importin-beta N-terminal domain DUF3385 PF11865.8 OAP55364.1 - 0.011 15.6 3.8 0.12 12.2 0.0 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF3385) Hemocyanin_M PF00372.19 OAP55364.1 - 0.026 13.7 0.0 0.054 12.7 0.0 1.4 1 0 0 1 1 1 0 Hemocyanin, copper containing domain Pre-PUA PF17832.1 OAP55364.1 - 0.039 14.6 0.5 0.54 11.0 0.0 3.1 3 1 0 3 3 3 0 Pre-PUA-like domain bZIP_2 PF07716.15 OAP55365.1 - 7.6e-13 48.3 16.8 1.7e-12 47.2 16.8 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 OAP55365.1 - 9.9e-05 22.4 12.0 9.9e-05 22.4 12.0 1.7 2 0 0 2 2 2 1 bZIP transcription factor TSC22 PF01166.18 OAP55365.1 - 0.055 13.8 2.3 0.11 12.8 2.3 1.5 1 0 0 1 1 1 0 TSC-22/dip/bun family UPF0242 PF06785.11 OAP55365.1 - 0.13 12.4 12.3 0.19 11.8 12.3 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus FapA PF03961.13 OAP55365.1 - 0.89 8.1 7.4 1.1 7.7 7.4 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A OmpH PF03938.14 OAP55365.1 - 1.6 9.1 15.5 2.7 8.3 15.5 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) YabA PF06156.13 OAP55365.1 - 2.7 8.7 8.1 4 8.1 7.3 1.6 1 1 0 1 1 1 0 Initiation control protein YabA HSP70 PF00012.20 OAP55365.1 - 8.8 4.4 13.4 12 4.0 13.4 1.1 1 0 0 1 1 1 0 Hsp70 protein CENP-N PF05238.13 OAP55366.1 - 3.5e-80 270.4 0.0 4.5e-80 270.0 0.0 1.0 1 0 0 1 1 1 1 Kinetochore protein CHL4 like adh_short_C2 PF13561.6 OAP55367.1 - 5.7e-23 81.7 0.8 7.6e-23 81.3 0.8 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP55367.1 - 1.9e-16 60.1 0.8 2.7e-16 59.6 0.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase 3HCDH_N PF02737.18 OAP55367.1 - 0.00096 19.1 0.6 0.0015 18.4 0.6 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ADH_zinc_N PF00107.26 OAP55367.1 - 0.0012 18.8 0.8 0.0023 17.9 0.8 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_7 PF13241.6 OAP55367.1 - 0.0016 18.9 0.3 0.05 14.1 0.2 2.2 2 0 0 2 2 2 1 Putative NAD(P)-binding KR PF08659.10 OAP55367.1 - 0.0017 18.3 0.7 0.0022 17.9 0.7 1.2 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.17 OAP55367.1 - 0.0065 17.0 0.3 0.058 14.0 0.1 2.4 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent THF_DHG_CYH_C PF02882.19 OAP55367.1 - 0.051 12.9 0.0 0.1 11.9 0.0 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 2-Hacid_dh_C PF02826.19 OAP55367.1 - 0.072 12.5 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N PF00107.26 OAP55368.1 - 3.2e-24 85.4 0.0 6.1e-24 84.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Fungal_trans PF04082.18 OAP55368.1 - 6.5e-21 74.5 0.1 1e-20 73.9 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain ADH_zinc_N_2 PF13602.6 OAP55368.1 - 6e-18 66.2 0.0 1.4e-17 65.0 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAP55368.1 - 4.2e-05 23.4 0.1 9.4e-05 22.3 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Gal4_dimer PF03902.13 OAP55368.1 - 0.0018 18.4 0.2 0.0048 17.0 0.2 1.7 1 0 0 1 1 1 1 Gal4-like dimerisation domain CAP_N PF01213.19 OAP55369.1 - 1.7e-114 382.6 0.0 3e-114 381.8 0.0 1.4 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 OAP55369.1 - 2e-58 196.5 3.6 2.7e-58 196.0 3.6 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.12 OAP55369.1 - 0.15 11.8 3.7 0.21 11.3 2.5 1.8 1 1 1 2 2 2 0 Tubulin binding cofactor C DEC-1_N PF04625.13 OAP55369.1 - 4.6 6.2 17.5 2.1 7.2 9.8 2.1 2 0 0 2 2 2 0 DEC-1 protein, N-terminal region Metallophos PF00149.28 OAP55370.1 - 4.4e-11 43.7 0.7 1.2e-10 42.3 0.7 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OAP55370.1 - 4.5e-08 33.4 0.1 5.9e-05 23.3 0.0 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain PPR_3 PF13812.6 OAP55371.1 - 0.0027 17.8 0.0 2 8.5 0.0 3.2 3 0 0 3 3 3 1 Pentatricopeptide repeat domain PPR_long PF17177.4 OAP55371.1 - 0.0094 15.3 0.0 0.19 11.1 0.0 2.1 2 0 0 2 2 2 1 Pentacotripeptide-repeat region of PRORP Abhydrolase_6 PF12697.7 OAP55372.1 - 2.9e-16 60.7 0.0 3.4e-16 60.5 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAP55372.1 - 0.0029 16.9 0.0 0.16 11.2 0.0 2.5 3 0 0 3 3 3 1 Serine aminopeptidase, S33 DUF900 PF05990.12 OAP55372.1 - 0.011 15.3 0.0 0.023 14.2 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_1 PF00561.20 OAP55372.1 - 0.033 13.8 0.0 0.075 12.7 0.0 1.6 2 0 0 2 2 2 0 alpha/beta hydrolase fold PGAP1 PF07819.13 OAP55372.1 - 0.061 13.0 0.0 0.14 11.8 0.0 1.6 2 0 0 2 2 2 0 PGAP1-like protein LIDHydrolase PF10230.9 OAP55372.1 - 0.074 12.6 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase DUF722 PF05263.11 OAP55373.1 - 0.044 14.0 0.4 4.2 7.6 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF722) LPG_synthase_TM PF03706.13 OAP55373.1 - 0.11 12.0 0.3 0.17 11.4 0.3 1.1 1 0 0 1 1 1 0 Lysylphosphatidylglycerol synthase TM region MaAIMP_sms PF16951.5 OAP55373.1 - 0.16 11.7 0.5 0.37 10.6 0.5 1.5 1 0 0 1 1 1 0 Putative methionine and alanine importer, small subunit HemY_N PF07219.13 OAP55373.1 - 0.23 11.7 2.4 0.43 10.8 1.9 1.7 2 0 0 2 2 2 0 HemY protein N-terminus CTP_transf_1 PF01148.20 OAP55375.1 - 4.5e-79 266.0 23.5 5.7e-79 265.6 23.5 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family DUF3636 PF12331.8 OAP55376.1 - 7.4e-45 152.4 1.8 1.4e-44 151.5 1.8 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3636) LCD1 PF09798.9 OAP55376.1 - 1.9e-06 26.7 8.7 0.00021 20.0 0.9 3.1 2 1 0 3 3 3 2 DNA damage checkpoint protein Leu_zip PF15294.6 OAP55376.1 - 0.026 14.0 4.1 0.15 11.5 3.3 2.2 1 1 1 2 2 2 0 Leucine zipper Phage_GPO PF05929.11 OAP55376.1 - 0.032 13.9 4.1 0.062 12.9 4.1 1.4 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Golgin_A5 PF09787.9 OAP55376.1 - 0.045 13.2 7.9 0.079 12.4 7.9 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 Tho2 PF11262.8 OAP55376.1 - 0.35 10.0 3.9 0.6 9.3 3.9 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Lebercilin PF15619.6 OAP55376.1 - 0.48 10.1 12.6 0.042 13.5 5.0 2.3 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Jnk-SapK_ap_N PF09744.9 OAP55376.1 - 0.82 9.9 9.0 1.6 8.9 9.0 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Mod_r PF07200.13 OAP55376.1 - 9.9 6.3 11.7 12 6.0 7.7 2.6 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein NICE-3 PF07406.11 OAP55377.1 - 0.0097 15.9 0.0 0.02 14.9 0.0 1.5 1 0 0 1 1 1 1 NICE-3 protein DUF4129 PF13559.6 OAP55377.1 - 0.063 13.5 0.0 0.14 12.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4129) DUF1993 PF09351.10 OAP55378.1 - 3.2e-56 189.9 0.0 3.6e-56 189.8 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) Cupin_2 PF07883.11 OAP55379.1 - 2e-11 43.4 0.1 3.7e-11 42.6 0.1 1.5 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 OAP55379.1 - 4.3e-05 23.1 0.0 6.5e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Cupin MannoseP_isomer PF01050.18 OAP55379.1 - 0.0047 16.8 0.0 0.0062 16.4 0.0 1.1 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase PTH2 PF01981.16 OAP55380.1 - 4.2e-41 139.9 0.2 5.8e-41 139.5 0.2 1.2 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 GCIP PF13324.6 OAP55380.1 - 0.026 14.1 0.8 0.033 13.8 0.8 1.1 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting VEFS-Box PF09733.9 OAP55380.1 - 0.026 14.3 0.8 0.036 13.9 0.8 1.2 1 0 0 1 1 1 0 VEFS-Box of polycomb protein DUF688 PF05097.12 OAP55380.1 - 0.26 10.4 2.9 0.36 9.9 2.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF688) DNA_pol_phi PF04931.13 OAP55380.1 - 2.1 6.4 6.9 2.6 6.0 6.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 OAP55380.1 - 4.1 6.6 9.3 6.5 6.0 9.3 1.3 1 0 0 1 1 1 0 NOA36 protein GFO_IDH_MocA PF01408.22 OAP55381.1 - 1.2e-20 74.5 0.0 1.6e-19 70.9 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 OAP55381.1 - 0.12 13.0 0.1 0.26 11.9 0.1 1.5 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain F420_oxidored PF03807.17 OAP55381.1 - 0.16 12.6 0.4 0.69 10.5 0.0 2.1 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent PALP PF00291.25 OAP55382.1 - 5.5e-61 206.6 0.0 6.2e-61 206.4 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme APH PF01636.23 OAP55383.1 - 0.0002 21.4 3.4 0.00023 21.2 0.0 2.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family Alanine_zipper PF11839.8 OAP55383.1 - 0.0003 21.1 20.5 0.00084 19.7 20.5 1.7 1 0 0 1 1 1 1 Alanine-zipper, major outer membrane lipoprotein Choline_kinase PF01633.20 OAP55383.1 - 0.0027 17.3 0.0 0.0053 16.4 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 OAP55383.1 - 0.028 13.8 0.4 0.028 13.8 0.4 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family RYDR_ITPR PF01365.21 OAP55383.1 - 0.11 11.9 0.0 0.25 10.7 0.0 1.6 1 0 0 1 1 1 0 RIH domain RIO1 PF01163.22 OAP55383.1 - 0.12 12.0 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Pkinase PF00069.25 OAP55383.1 - 0.15 11.4 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain XhlA PF10779.9 OAP55383.1 - 0.16 12.2 2.8 0.49 10.6 2.0 2.0 1 1 0 1 1 1 0 Haemolysin XhlA Tropomyosin PF00261.20 OAP55383.1 - 0.25 10.7 8.5 0.71 9.2 8.5 1.8 1 0 0 1 1 1 0 Tropomyosin Borrelia_P83 PF05262.11 OAP55383.1 - 0.44 9.0 2.9 0.67 8.4 2.9 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein PfkB PF00294.24 OAP55384.1 - 5e-08 32.6 0.1 2.6e-07 30.3 0.1 2.0 2 1 0 2 2 2 1 pfkB family carbohydrate kinase Utp14 PF04615.13 OAP55384.1 - 0.22 10.1 0.8 0.28 9.7 0.8 1.1 1 0 0 1 1 1 0 Utp14 protein ADH_zinc_N PF00107.26 OAP55386.1 - 2.7e-10 40.3 0.2 5e-10 39.5 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAP55386.1 - 9.4e-10 38.4 0.0 1.6e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 OAP55386.1 - 0.0045 18.1 0.1 0.011 16.8 0.1 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Fungal_trans PF04082.18 OAP55387.1 - 2.1e-17 63.0 0.7 3.9e-17 62.2 0.1 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF4232 PF14016.6 OAP55388.1 - 0.088 12.9 0.3 0.22 11.7 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4232) Ribonucleas_3_3 PF14622.6 OAP55389.1 - 1.5e-07 31.6 0.0 0.0012 19.0 0.0 2.6 2 1 0 2 2 2 2 Ribonuclease-III-like dsrm PF00035.26 OAP55389.1 - 5.4e-07 30.2 0.0 1.5e-06 28.8 0.0 1.8 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonuclease_3 PF00636.26 OAP55389.1 - 0.013 16.1 0.1 0.19 12.4 0.0 2.5 2 1 0 2 2 2 0 Ribonuclease III domain Gly-zipper_Omp PF13488.6 OAP55390.1 - 0.007 16.3 3.5 0.011 15.7 3.5 1.2 1 0 0 1 1 1 1 Glycine zipper Rick_17kDa_Anti PF05433.15 OAP55390.1 - 0.33 10.9 10.6 0.48 10.3 10.6 1.3 1 0 0 1 1 1 0 Glycine zipper 2TM domain Gly-zipper_YMGG PF13441.6 OAP55390.1 - 0.49 10.2 6.4 0.76 9.6 6.4 1.3 1 0 0 1 1 1 0 YMGG-like Gly-zipper Meth_synt_2 PF01717.18 OAP55392.1 - 1.8e-09 37.3 0.0 2e-06 27.3 0.0 2.4 2 1 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 OAP55392.1 - 0.087 12.3 0.0 0.26 10.7 0.0 1.7 2 0 0 2 2 2 0 Cobalamin-independent synthase, N-terminal domain F-box-like PF12937.7 OAP55393.1 - 0.002 18.0 0.3 0.0091 15.9 0.3 2.3 1 0 0 1 1 1 1 F-box-like AzlD PF05437.12 OAP55393.1 - 0.15 12.2 0.8 0.66 10.2 0.4 2.2 1 1 0 1 1 1 0 Branched-chain amino acid transport protein (AzlD) DUF3425 PF11905.8 OAP55394.1 - 8.5e-10 38.7 0.0 1.8e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Zn_clus PF00172.18 OAP55394.1 - 2.1e-09 37.4 3.9 3.6e-09 36.6 3.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_14 PF13428.6 OAP55394.1 - 0.57 11.2 2.7 2 9.5 0.3 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-C2H2 PF00096.26 OAP55395.1 - 0.00051 20.4 15.7 0.47 11.0 2.0 4.5 4 1 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_aberr PF17017.5 OAP55395.1 - 0.00087 19.5 0.1 0.00087 19.5 0.1 1.7 2 0 0 2 2 2 1 Aberrant zinc-finger DGF-1_C PF11040.8 OAP55395.1 - 0.18 11.8 0.9 0.35 10.9 0.1 1.9 2 0 0 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus zf-C2H2_4 PF13894.6 OAP55395.1 - 0.94 10.5 13.9 11 7.2 0.1 4.2 4 1 0 4 4 4 0 C2H2-type zinc finger Choline_transpo PF04515.12 OAP55396.1 - 3.8e-81 272.8 24.0 3.8e-81 272.8 24.0 2.1 2 0 0 2 2 2 1 Plasma-membrane choline transporter Pex14_N PF04695.13 OAP55396.1 - 0.97 10.1 7.1 2.1 9.0 7.1 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region NCE101 PF11654.8 OAP55396.1 - 0.99 9.2 5.1 0.16 11.7 0.4 2.1 2 0 0 2 2 2 0 Non-classical export protein 1 HTH_43 PF09904.9 OAP55397.1 - 0.16 11.9 0.0 0.37 10.8 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn helix DUF2108 PF09881.9 OAP55397.1 - 0.21 11.6 1.5 0.43 10.6 1.5 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2108) Ecl1 PF12855.7 OAP55398.1 - 4.2e-08 34.6 7.5 5.3e-08 34.2 7.5 1.1 1 0 0 1 1 1 1 ECL1/2/3 zinc binding proteins PPR_2 PF13041.6 OAP55399.1 - 3e-22 78.5 3.1 3.6e-08 33.5 0.0 7.7 8 1 2 10 10 10 4 PPR repeat family PPR_3 PF13812.6 OAP55399.1 - 5.5e-21 74.4 0.0 0.00027 20.9 0.0 7.4 7 1 1 8 8 8 5 Pentatricopeptide repeat domain PPR PF01535.20 OAP55399.1 - 1.3e-17 62.8 0.0 0.0068 16.6 0.0 9.7 11 0 0 11 11 11 3 PPR repeat PPR_long PF17177.4 OAP55399.1 - 1e-13 51.2 0.2 3.7e-08 33.0 0.0 5.7 3 1 4 7 7 7 2 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 OAP55399.1 - 1.6e-10 40.5 0.0 0.013 15.2 0.0 5.8 7 0 0 7 7 7 3 PPR repeat TPR_14 PF13428.6 OAP55399.1 - 0.0039 17.9 4.7 32 5.7 0.1 6.3 6 1 0 6 6 6 0 Tetratricopeptide repeat SRP68 PF16969.5 OAP55400.1 - 7.1e-173 576.6 0.7 8.1e-173 576.4 0.7 1.0 1 0 0 1 1 1 1 RNA-binding signal recognition particle 68 BRO1 PF03097.18 OAP55400.1 - 0.036 12.9 0.0 0.085 11.6 0.0 1.6 2 0 0 2 2 2 0 BRO1-like domain TPP_enzyme_N PF02776.18 OAP55401.1 - 2.1e-31 108.9 0.6 5.2e-31 107.5 0.6 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 OAP55401.1 - 5.7e-18 65.0 0.0 1.1e-17 64.1 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 OAP55401.1 - 2.7e-15 56.5 0.0 6.8e-15 55.2 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain MatE PF01554.18 OAP55402.1 - 2.2e-51 173.7 21.0 7.7e-32 110.2 3.7 2.2 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 OAP55402.1 - 5.5e-05 23.3 8.9 5.5e-05 23.3 8.9 3.8 3 2 0 3 3 3 2 Polysaccharide biosynthesis C-terminal domain RabGAP-TBC PF00566.18 OAP55403.1 - 3.6e-32 111.8 0.0 8.4e-32 110.6 0.0 1.6 1 1 0 1 1 1 1 Rab-GTPase-TBC domain COPIIcoated_ERV PF07970.12 OAP55404.1 - 1e-35 123.6 0.0 1.9e-35 122.7 0.0 1.4 1 1 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 OAP55404.1 - 1.6e-23 82.9 0.0 2.5e-23 82.2 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Methyltransf_25 PF13649.6 OAP55406.1 - 5.7e-13 49.4 0.0 1.4e-12 48.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAP55406.1 - 3.2e-11 43.7 0.0 6.2e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAP55406.1 - 1e-09 38.1 0.1 2.6e-09 36.8 0.0 1.6 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 OAP55406.1 - 2.9e-07 30.4 0.0 4.6e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAP55406.1 - 1.5e-05 24.9 0.0 2.3e-05 24.3 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAP55406.1 - 0.00021 22.0 0.0 0.00037 21.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OAP55406.1 - 0.00094 18.8 0.0 0.0024 17.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase small domain Cep57_MT_bd PF06657.13 OAP55407.1 - 0.36 11.3 3.3 0.19 12.2 0.3 2.0 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 APG6_N PF17675.1 OAP55408.1 - 0.0034 17.9 23.8 0.41 11.2 3.1 3.4 1 1 1 2 2 2 2 Apg6 coiled-coil region Tropomyosin_1 PF12718.7 OAP55408.1 - 0.011 15.8 13.1 0.011 15.8 13.1 2.5 2 1 0 2 2 2 0 Tropomyosin like Mei5 PF10376.9 OAP55408.1 - 0.054 13.3 6.1 0.12 12.3 6.1 1.5 1 0 0 1 1 1 0 Double-strand recombination repair protein ATG16 PF08614.11 OAP55408.1 - 0.071 13.3 25.4 1.4 9.1 16.8 3.0 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Leu_zip PF15294.6 OAP55408.1 - 0.14 11.7 11.5 0.5 9.8 1.1 2.3 1 1 1 2 2 2 0 Leucine zipper Prefoldin PF02996.17 OAP55408.1 - 0.47 10.4 12.5 22 5.0 0.1 4.5 3 1 0 4 4 4 0 Prefoldin subunit Amidinotransf PF02274.17 OAP55408.1 - 0.66 9.0 4.2 1.1 8.3 4.2 1.2 1 0 0 1 1 1 0 Amidinotransferase PI3K_P85_iSH2 PF16454.5 OAP55408.1 - 0.75 9.4 17.1 0.43 10.2 8.3 3.3 2 1 1 3 3 3 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF724 PF05266.14 OAP55408.1 - 0.77 9.6 13.8 0.14 11.9 4.8 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF724) DUF3450 PF11932.8 OAP55408.1 - 2.6 7.3 20.8 7.5 5.8 11.9 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) Fez1 PF06818.15 OAP55408.1 - 3.4 8.1 20.4 90 3.4 20.4 2.2 1 1 0 1 1 1 0 Fez1 GAS PF13851.6 OAP55408.1 - 3.9 6.8 22.5 0.87 8.9 11.3 2.6 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.9 OAP55408.1 - 4.1 7.4 22.9 12 5.9 9.7 3.3 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 JIP_LZII PF16471.5 OAP55408.1 - 7.5 6.8 15.9 0.92 9.7 1.2 4.2 3 2 2 5 5 5 0 JNK-interacting protein leucine zipper II WD40 PF00400.32 OAP55409.1 - 2.1e-17 63.2 16.2 2.4e-06 28.2 0.5 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAP55409.1 - 0.033 14.5 0.0 0.29 11.5 0.0 2.5 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain PS_Dcarbxylase PF02666.15 OAP55410.1 - 7.9e-53 179.0 0.0 1e-52 178.6 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase SET PF00856.28 OAP55411.1 - 0.00026 21.4 0.0 0.0019 18.6 0.0 2.3 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.18 OAP55411.1 - 0.0051 16.9 6.5 0.0051 16.9 6.5 2.3 2 0 0 2 2 2 1 MYND finger DDE_Tnp_IS66_C PF13817.6 OAP55411.1 - 0.081 13.2 0.0 0.33 11.2 0.0 2.0 1 0 0 1 1 1 0 IS66 C-terminal element PAP2 PF01569.21 OAP55412.1 - 3.1e-23 82.1 3.5 7.6e-23 80.8 3.5 1.6 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 OAP55412.1 - 1.7 8.3 14.6 2.4 7.8 8.7 3.1 2 1 0 2 2 2 0 PAP2 superfamily DUF3976 PF13121.6 OAP55412.1 - 6.5 7.0 6.9 4.1 7.6 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3976) Spo7 PF03907.13 OAP55413.1 - 6.5e-84 280.8 0.3 1.5e-83 279.6 0.3 1.6 1 0 0 1 1 1 1 Spo7-like protein SVIP PF15811.5 OAP55413.1 - 0.98 9.9 21.1 0.41 11.1 16.4 2.5 2 0 0 2 2 2 0 Small VCP/p97-interacting protein Abhydrolase_1 PF00561.20 OAP55414.1 - 3.3e-21 76.1 0.0 3.4e-19 69.5 0.0 2.5 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAP55414.1 - 4.4e-17 63.4 1.7 1.6e-15 58.3 1.7 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAP55414.1 - 1.2e-16 60.7 0.0 5.5e-16 58.6 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Esterase PF00756.20 OAP55414.1 - 7.7e-07 29.0 0.0 1.7e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Putative esterase DUF915 PF06028.11 OAP55414.1 - 0.00018 20.9 0.0 0.00031 20.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) LIDHydrolase PF10230.9 OAP55414.1 - 0.0015 18.1 0.0 0.0036 16.9 0.0 1.6 2 0 0 2 2 2 1 Lipid-droplet associated hydrolase Abhydrolase_2 PF02230.16 OAP55414.1 - 0.0023 17.8 0.0 1.6 8.5 0.0 3.0 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Chlorophyllase2 PF12740.7 OAP55414.1 - 0.0055 15.6 0.0 0.0094 14.9 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 OAP55414.1 - 0.043 12.8 0.0 0.073 12.1 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase PGAP1 PF07819.13 OAP55414.1 - 0.067 12.9 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_3 PF07859.13 OAP55414.1 - 0.091 12.6 0.0 0.38 10.6 0.0 1.9 2 0 0 2 2 2 0 alpha/beta hydrolase fold Lipase_3 PF01764.25 OAP55414.1 - 0.15 11.9 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) ADH_zinc_N PF00107.26 OAP55415.1 - 2e-11 44.0 0.1 8.3e-11 42.0 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAP55415.1 - 1.5e-05 24.8 0.2 0.00021 21.1 0.1 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 OAP55415.1 - 0.00055 21.0 0.0 0.0012 19.9 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.6 OAP55416.1 - 9.5e-09 35.4 0.1 5.6e-06 26.4 0.0 3.0 3 0 0 3 3 3 2 NAD(P)H-binding NmrA PF05368.13 OAP55416.1 - 3.1e-07 30.2 0.0 6e-06 26.0 0.0 2.1 1 1 0 1 1 1 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 OAP55416.1 - 0.0019 18.4 0.0 0.0044 17.3 0.0 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain KR PF08659.10 OAP55416.1 - 0.02 14.8 0.2 0.036 14.0 0.2 1.4 1 0 0 1 1 1 0 KR domain Homeodomain PF00046.29 OAP55417.1 - 3.2e-14 52.5 0.8 3.2e-14 52.5 0.8 1.7 2 0 0 2 2 2 1 Homeodomain Amino_oxidase PF01593.24 OAP55418.1 - 1.6e-46 159.5 0.2 3.2e-46 158.6 0.2 1.5 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OAP55418.1 - 1.1e-16 60.9 0.4 2.4e-16 59.7 0.4 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAP55418.1 - 1.2e-06 28.0 0.5 2e-06 27.2 0.1 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAP55418.1 - 5.1e-06 26.3 7.2 4.4e-05 23.2 7.2 2.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 OAP55418.1 - 8e-06 26.3 0.9 3.4e-05 24.3 0.2 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAP55418.1 - 0.00017 20.8 0.9 0.00072 18.8 0.4 2.1 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 OAP55418.1 - 0.00025 19.9 0.4 0.00057 18.7 0.2 1.7 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_9 PF13454.6 OAP55418.1 - 0.00025 21.1 0.9 0.25 11.3 0.2 2.7 2 1 0 2 2 2 2 FAD-NAD(P)-binding Thi4 PF01946.17 OAP55418.1 - 0.00037 19.8 0.1 0.00062 19.1 0.1 1.3 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 OAP55418.1 - 0.00046 19.4 0.4 0.00086 18.5 0.4 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 OAP55418.1 - 0.00091 18.7 0.2 0.0014 18.0 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 OAP55418.1 - 0.0014 17.9 0.5 0.0025 17.1 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain 3HCDH_N PF02737.18 OAP55418.1 - 0.0053 16.6 0.3 0.011 15.6 0.3 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 OAP55418.1 - 0.0059 15.9 0.0 0.012 14.9 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 OAP55418.1 - 0.18 10.8 0.2 0.32 10.0 0.2 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Lactamase_B_2 PF12706.7 OAP55420.1 - 2.8e-24 85.8 0.0 4.5e-24 85.1 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 OAP55420.1 - 1.4e-05 25.1 0.0 4.3e-05 23.5 0.0 1.8 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Protoglobin PF11563.8 OAP55421.1 - 4.3e-52 176.2 0.3 5.4e-52 175.9 0.3 1.1 1 0 0 1 1 1 1 Protoglobin Hexapep PF00132.24 OAP55422.1 - 3.5e-12 45.5 4.1 4.7e-06 26.1 0.5 4.6 3 1 1 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 OAP55422.1 - 0.0013 18.5 0.3 0.011 15.4 0.1 2.7 4 0 0 4 4 4 1 Hexapeptide repeat of succinyl-transferase FeoB_associated PF12669.7 OAP55424.1 - 0.16 12.4 0.4 0.27 11.7 0.4 1.3 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein Cyclin_N PF00134.23 OAP55426.1 - 1.8e-11 43.9 0.0 3.3e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 OAP55426.1 - 4.2e-07 30.5 0.0 8.9e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 Cyclin PIG-F PF06699.11 OAP55427.1 - 1.6e-46 158.7 6.2 2.3e-46 158.2 6.2 1.2 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F Tiam_CC_Ex PF18385.1 OAP55428.1 - 0.025 15.0 0.0 0.052 13.9 0.0 1.5 1 0 0 1 1 1 0 T-lymphoma invasion and metastasis CC-Ex domain CLZ PF16526.5 OAP55428.1 - 0.092 13.1 0.6 1.1 9.7 0.5 2.2 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels EzrA PF06160.12 OAP55428.1 - 0.21 9.7 0.3 0.29 9.3 0.3 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA AAA_11 PF13086.6 OAP55429.1 - 7.6e-60 202.9 0.0 1.8e-59 201.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.6 OAP55429.1 - 2e-56 190.8 0.0 5.6e-56 189.3 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 OAP55429.1 - 1.4e-12 47.7 0.0 4e-11 43.0 0.0 2.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OAP55429.1 - 1.7e-10 41.4 0.0 1e-09 38.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.9 OAP55429.1 - 3.2e-08 33.2 0.0 2.2e-07 30.5 0.0 2.0 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.18 OAP55429.1 - 1.9e-06 27.8 0.0 0.16 11.7 0.0 3.3 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 OAP55429.1 - 2.3e-06 27.7 0.0 8.2e-06 25.9 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 OAP55429.1 - 1.6e-05 24.6 0.0 4.4e-05 23.2 0.0 1.6 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain PIF1 PF05970.14 OAP55429.1 - 6.2e-05 22.3 0.0 0.2 10.8 0.0 2.2 2 0 0 2 2 2 2 PIF1-like helicase AAA_22 PF13401.6 OAP55429.1 - 0.0001 22.6 0.2 0.0026 18.0 0.1 2.9 2 1 0 2 2 1 1 AAA domain Helicase_RecD PF05127.14 OAP55429.1 - 0.00027 20.8 0.0 0.041 13.7 0.0 3.1 2 1 0 2 2 2 1 Helicase AAA_16 PF13191.6 OAP55429.1 - 0.00038 20.9 0.0 0.0013 19.1 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain PhoH PF02562.16 OAP55429.1 - 0.0016 17.9 0.0 0.025 14.0 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein AAA_5 PF07728.14 OAP55429.1 - 0.0028 17.7 0.1 0.03 14.3 0.0 2.6 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) T2SSE PF00437.20 OAP55429.1 - 0.004 16.3 0.0 0.013 14.5 0.0 1.8 2 0 0 2 2 2 1 Type II/IV secretion system protein DEAD PF00270.29 OAP55429.1 - 0.0092 15.8 0.0 0.1 12.3 0.0 2.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase UvrD_C PF13361.6 OAP55429.1 - 0.0097 15.3 0.0 1.6 8.0 0.0 2.6 2 1 0 3 3 3 1 UvrD-like helicase C-terminal domain AAA_10 PF12846.7 OAP55429.1 - 0.014 14.4 0.0 0.022 13.7 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA PF00004.29 OAP55429.1 - 0.017 15.6 0.0 0.064 13.7 0.0 2.0 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 OAP55429.1 - 0.018 14.6 0.1 0.35 10.4 0.0 2.7 2 1 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.9 OAP55429.1 - 0.023 13.6 0.0 0.041 12.8 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain UvrD_C_2 PF13538.6 OAP55429.1 - 0.035 13.9 0.1 0.15 11.9 0.0 2.0 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain AAA_24 PF13479.6 OAP55429.1 - 0.049 13.3 0.0 0.52 10.0 0.0 2.3 1 1 0 1 1 1 0 AAA domain 4HB_MCP_1 PF12729.7 OAP55429.1 - 0.062 12.8 0.5 0.36 10.4 0.0 2.1 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction ABC_tran PF00005.27 OAP55429.1 - 0.075 13.5 0.0 0.22 12.0 0.0 1.9 2 0 0 2 2 1 0 ABC transporter Zot PF05707.12 OAP55429.1 - 0.1 12.3 0.0 0.3 10.7 0.0 1.8 1 1 1 2 2 2 0 Zonular occludens toxin (Zot) NTPase_1 PF03266.15 OAP55429.1 - 0.12 12.3 0.2 1.5 8.7 0.0 2.4 2 0 0 2 2 2 0 NTPase Flavi_DEAD PF07652.14 OAP55429.1 - 0.15 12.0 0.0 0.72 9.8 0.0 2.2 3 0 0 3 3 2 0 Flavivirus DEAD domain AAA_23 PF13476.6 OAP55429.1 - 2.4 8.6 0.0 2.4 8.6 0.0 2.5 2 1 0 2 2 2 0 AAA domain Methyltransf_23 PF13489.6 OAP55430.1 - 1.6e-16 60.6 0.0 9.3e-16 58.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAP55430.1 - 7.9e-09 36.1 0.0 1.9e-08 34.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAP55430.1 - 2.8e-06 27.9 0.0 8.7e-06 26.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAP55430.1 - 0.00016 21.5 0.0 0.00069 19.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAP55430.1 - 0.0028 18.4 0.0 0.0098 16.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OAP55430.1 - 0.0034 16.9 0.0 0.0056 16.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.19 OAP55430.1 - 0.012 15.7 0.0 0.021 14.9 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_4 PF02390.17 OAP55430.1 - 0.016 14.6 0.0 0.031 13.8 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase PrmA PF06325.13 OAP55430.1 - 0.069 12.5 0.0 0.098 12.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Met_10 PF02475.16 OAP55430.1 - 0.13 12.0 0.4 0.49 10.1 0.1 1.9 2 0 0 2 2 2 0 Met-10+ like-protein p450 PF00067.22 OAP55431.1 - 9.2e-50 169.7 0.0 3e-49 168.0 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 RINGv PF12906.7 OAP55432.1 - 5.1e-06 26.5 3.8 8e-06 25.9 1.7 2.2 2 0 0 2 2 2 1 RING-variant domain UPF0547 PF10571.9 OAP55432.1 - 5.8 7.1 5.7 1.2 9.2 1.3 2.0 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 DNA_pol3_delta2 PF13177.6 OAP55434.1 - 2.9e-10 40.1 0.0 5.6e-10 39.2 0.0 1.4 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 OAP55434.1 - 2.6e-06 27.9 0.2 7.9e-06 26.3 0.1 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OAP55434.1 - 0.00071 19.9 0.3 0.0035 17.6 0.2 2.2 2 1 0 2 2 2 1 AAA domain Rep_fac_C PF08542.11 OAP55434.1 - 0.0032 17.8 0.2 0.0071 16.7 0.0 1.7 2 0 0 2 2 2 1 Replication factor C C-terminal domain AAA_30 PF13604.6 OAP55434.1 - 0.007 16.1 0.1 0.013 15.3 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OAP55434.1 - 0.013 15.9 1.8 0.096 13.1 0.4 2.7 2 2 0 2 2 2 0 AAA ATPase domain AAA_24 PF13479.6 OAP55434.1 - 0.029 14.1 0.1 0.068 12.9 0.1 1.6 1 1 0 1 1 1 0 AAA domain Resolvase PF00239.21 OAP55434.1 - 0.07 13.2 1.9 0.27 11.3 0.3 2.7 3 1 0 3 3 3 0 Resolvase, N terminal domain RuvB_N PF05496.12 OAP55434.1 - 0.091 12.5 0.0 1.9 8.2 0.0 2.3 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain DNA_pol3_delta PF06144.13 OAP55434.1 - 0.12 12.2 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase III, delta subunit AAA_29 PF13555.6 OAP55434.1 - 0.17 11.6 0.1 1.7 8.4 0.0 2.5 2 1 1 3 3 3 0 P-loop containing region of AAA domain Ribonuclease_3 PF00636.26 OAP55435.1 - 2.6e-35 121.2 0.0 8.6e-19 68.1 0.0 3.0 3 0 0 3 3 3 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 OAP55435.1 - 2.9e-24 85.6 0.0 1.5e-11 44.6 0.0 3.7 3 0 0 3 3 3 3 Ribonuclease-III-like Dicer_dimer PF03368.14 OAP55435.1 - 4.6e-20 71.6 0.0 1.8e-19 69.7 0.0 2.0 1 0 0 1 1 1 1 Dicer dimerisation domain DEAD PF00270.29 OAP55435.1 - 9.4e-15 54.8 0.0 4.2e-14 52.7 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAP55435.1 - 7.2e-12 45.6 0.0 1.8e-11 44.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAP55435.1 - 3.4e-10 40.2 0.0 9.6e-10 38.7 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 OAP55435.1 - 0.12 12.7 0.0 0.47 10.7 0.0 2.0 1 0 0 1 1 1 0 AAA domain dsrm PF00035.26 OAP55435.1 - 0.25 12.1 2.0 5.4 7.8 0.4 2.9 2 0 0 2 2 2 0 Double-stranded RNA binding motif EF-hand_6 PF13405.6 OAP55436.1 - 0.0026 17.5 0.2 0.0077 16.1 0.0 1.9 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 OAP55436.1 - 0.032 14.7 0.0 0.1 13.0 0.0 1.8 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_5 PF13202.6 OAP55436.1 - 0.035 13.6 0.0 0.096 12.2 0.0 1.7 1 0 0 1 1 1 0 EF hand EF-hand_1 PF00036.32 OAP55436.1 - 0.083 12.5 0.1 0.34 10.6 0.0 2.0 2 0 0 2 2 2 0 EF hand Isochorismatase PF00857.20 OAP55437.1 - 2e-19 70.4 0.0 6.1e-19 68.9 0.0 1.7 1 1 0 1 1 1 1 Isochorismatase family Methyltransf_11 PF08241.12 OAP55438.1 - 2.4e-06 28.1 0.0 7.4e-06 26.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAP55438.1 - 0.051 14.3 0.0 0.15 12.8 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain His_Phos_1 PF00300.22 OAP55439.1 - 7.1e-35 120.5 0.4 1.1e-17 64.4 0.1 2.4 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) ArfGap PF01412.18 OAP55441.1 - 5.9e-34 116.6 0.5 5.9e-34 116.6 0.5 1.5 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf DUF4337 PF14235.6 OAP55441.1 - 0.16 12.1 0.2 0.16 12.1 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) CHCH PF06747.13 OAP55443.1 - 3.1e-06 27.2 5.7 4.8e-06 26.5 5.7 1.3 1 0 0 1 1 1 1 CHCH domain PP2C_C PF07830.13 OAP55443.1 - 0.46 11.0 2.6 0.41 11.1 0.7 1.8 2 0 0 2 2 2 0 Protein serine/threonine phosphatase 2C, C-terminal domain SgrT PF15894.5 OAP55444.1 - 0.0026 17.7 0.0 0.0075 16.2 0.0 1.8 1 0 0 1 1 1 1 Inhibitor of glucose uptake transporter SgrT AAA_28 PF13521.6 OAP55444.1 - 0.15 12.3 0.8 3.4 7.9 0.0 3.0 4 0 0 4 4 4 0 AAA domain Glyco_hydro_85 PF03644.13 OAP55445.1 - 3.4e-55 187.6 0.1 5.6e-55 186.9 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 TPK_catalytic PF04263.16 OAP55446.1 - 8.8e-30 103.2 0.0 1.3e-29 102.7 0.0 1.2 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 OAP55446.1 - 3.2e-16 58.8 0.0 5.4e-16 58.1 0.0 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain MIF4G PF02854.19 OAP55447.1 - 1.2e-61 208.0 0.3 1.7e-33 116.1 0.1 3.4 3 0 0 3 3 3 3 MIF4G domain Upf2 PF04050.14 OAP55447.1 - 3.8e-20 73.0 19.5 6.3e-12 46.4 0.7 3.6 2 1 1 3 3 3 2 Up-frameshift suppressor 2 Fib_alpha PF08702.10 OAP55447.1 - 3.5 7.8 5.3 0.72 10.0 0.6 2.3 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Ribosomal_L1 PF00687.21 OAP55448.1 - 1.3e-57 194.9 1.7 1.9e-57 194.3 1.7 1.3 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Vfa1 PF08432.10 OAP55448.1 - 1.8 8.8 9.2 0.3 11.4 0.2 2.9 3 0 0 3 3 3 0 AAA-ATPase Vps4-associated protein 1 ETF PF01012.21 OAP55450.1 - 1.3e-44 152.3 0.4 2.5e-44 151.3 0.4 1.5 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 OAP55450.1 - 6.5e-34 115.8 0.1 1.2e-33 115.0 0.1 1.5 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain Fungal_trans PF04082.18 OAP55451.1 - 1.2e-07 31.1 0.2 2.5e-07 30.0 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP55451.1 - 6.2e-07 29.4 7.5 6.2e-07 29.4 7.5 2.6 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2039 PF10217.9 OAP55451.1 - 0.58 10.5 7.7 0.28 11.5 4.6 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) HLH PF00010.26 OAP55452.1 - 1.2e-09 38.0 0.0 4.2e-09 36.2 0.0 2.0 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain PBP1_TM PF14812.6 OAP55452.1 - 0.59 10.5 9.4 1.8 9.0 4.9 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FAM176 PF14851.6 OAP55452.1 - 0.78 9.4 7.3 2 8.1 1.4 2.5 2 0 0 2 2 2 0 FAM176 family HLH PF00010.26 OAP55453.1 - 1e-08 35.0 0.1 9.3e-08 31.9 0.0 2.3 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Spem1 PF15670.5 OAP55453.1 - 0.07 12.7 6.5 0.12 11.9 6.5 1.4 1 0 0 1 1 1 0 Spermatid maturation protein 1 DNA_pol_viral_N PF00242.17 OAP55453.1 - 3.7 6.9 12.6 5.4 6.4 12.6 1.2 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Fungal_trans PF04082.18 OAP55454.1 - 1e-09 37.9 3.8 1.6e-09 37.2 3.8 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP55454.1 - 4.4e-06 26.7 10.0 1e-05 25.6 10.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2039 PF10217.9 OAP55454.1 - 1.2 9.5 11.1 0.24 11.8 6.5 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) MFS_1 PF07690.16 OAP55455.1 - 1.2e-28 100.1 56.9 2.2e-18 66.3 27.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily HD_2 PF12917.7 OAP55456.1 - 0.012 15.4 4.0 0.02 14.7 4.0 1.3 1 0 0 1 1 1 0 HD containing hydrolase-like enzyme HTH_25 PF13413.6 OAP55456.1 - 0.14 12.0 0.2 0.67 9.9 0.1 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain NOA36 PF06524.12 OAP55457.1 - 0.93 8.7 9.2 1.2 8.3 9.2 1.2 1 0 0 1 1 1 0 NOA36 protein Ribosomal_60s PF00428.19 OAP55457.1 - 1.1 9.8 14.3 2.4 8.8 14.3 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein Nop14 PF04147.12 OAP55457.1 - 2.2 6.4 8.5 3.2 5.9 8.5 1.2 1 0 0 1 1 1 0 Nop14-like family adh_short PF00106.25 OAP55458.1 - 2.6e-30 105.4 0.1 3.5e-30 104.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP55458.1 - 7.1e-27 94.5 0.0 8.9e-27 94.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP55458.1 - 2.5e-09 37.3 0.0 3.7e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAP55458.1 - 0.0041 16.6 0.2 0.049 13.1 0.2 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Pex14_N PF04695.13 OAP55459.1 - 0.06 14.0 3.7 0.092 13.4 3.7 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Glyco_hydro_72 PF03198.14 OAP55460.1 - 7.2e-138 459.1 1.6 8.9e-138 458.8 1.6 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 OAP55460.1 - 5.2e-07 29.4 0.1 1.3e-06 28.1 0.1 1.6 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.17 OAP55460.1 - 0.00053 19.2 0.1 0.0015 17.7 0.1 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain DNA_binding_1 PF01035.20 OAP55461.1 - 1.4e-26 92.4 0.0 1.9e-26 92.0 0.0 1.2 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain NDUF_B7 PF05676.13 OAP55462.1 - 3.8e-28 97.0 4.4 4.8e-28 96.7 4.4 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.10 OAP55462.1 - 0.0011 18.9 2.2 0.0015 18.5 2.2 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like GCS PF03074.16 OAP55463.1 - 2.1e-170 566.9 0.0 2.7e-170 566.6 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase CorA PF01544.18 OAP55464.1 - 0.00027 20.3 0.0 0.00027 20.3 0.0 1.6 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein PalH PF08733.10 OAP55464.1 - 0.73 8.8 6.2 1.1 8.2 6.2 1.2 1 0 0 1 1 1 0 PalH/RIM21 Transp_cyt_pur PF02133.15 OAP55465.1 - 3.2e-148 494.2 43.8 3.7e-148 493.9 43.8 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin FAD_binding_4 PF01565.23 OAP55466.1 - 4e-23 81.7 0.2 1e-22 80.4 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 OAP55466.1 - 7e-14 51.7 1.3 1.4e-13 50.7 0.7 1.8 2 0 0 2 2 2 1 Berberine and berberine like Fungal_lectin PF07938.12 OAP55467.1 - 1.2e-07 31.4 0.0 2.7e-06 27.0 0.0 2.3 2 1 0 2 2 2 2 Fungal fucose-specific lectin zf-RING_4 PF14570.6 OAP55468.1 - 0.38 10.6 3.5 1.4 8.7 0.6 2.6 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain DUF3328 PF11807.8 OAP55469.1 - 0.00048 20.0 0.7 0.007 16.2 0.2 2.0 2 0 0 2 2 2 2 Domain of unknown function (DUF3328) DUF3328 PF11807.8 OAP55470.1 - 2.6e-08 33.9 3.3 2.5e-07 30.7 3.3 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.8 OAP55471.1 - 3e-48 164.5 3.1 1.1e-47 162.7 3.1 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) DUF1294 PF06961.13 OAP55471.1 - 0.063 13.5 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1294) TonB_N PF16031.5 OAP55472.1 - 0.0032 18.0 7.7 0.0032 18.0 7.7 5.1 4 1 0 5 5 5 3 TonB polyproline region Trypan_PARP PF05887.11 OAP55472.1 - 0.096 12.7 88.8 0.18 11.8 31.3 4.3 1 1 4 5 5 5 0 Procyclic acidic repetitive protein (PARP) MNNL PF07657.13 OAP55472.1 - 0.54 10.3 22.7 17 5.5 0.3 5.9 6 0 0 6 6 6 0 N terminus of Notch ligand CBM_19 PF03427.13 OAP55472.1 - 9.1 6.4 12.8 35 4.5 0.0 5.1 6 0 0 6 6 6 0 Carbohydrate binding domain (family 19) DUF1771 PF08590.10 OAP55473.1 - 1.1e-23 83.3 10.9 1.1e-23 83.3 10.9 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.21 OAP55473.1 - 9.5e-12 45.1 0.2 2.3e-11 43.9 0.2 1.7 1 0 0 1 1 1 1 Smr domain DUF4407 PF14362.6 OAP55473.1 - 0.52 9.6 3.7 0.77 9.0 3.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Fungal_trans PF04082.18 OAP55474.1 - 2.4e-13 49.7 0.1 5.4e-13 48.6 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain G-alpha PF00503.20 OAP55475.1 - 5.7e-125 417.1 1.1 6.6e-125 416.9 1.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 OAP55475.1 - 1.1e-15 57.6 1.1 1.4e-10 40.9 0.1 2.6 2 0 0 2 2 2 2 ADP-ribosylation factor family zf-CHC2 PF01807.20 OAP55475.1 - 0.00038 20.2 0.0 0.0016 18.2 0.0 1.9 2 0 0 2 2 2 1 CHC2 zinc finger Gtr1_RagA PF04670.12 OAP55475.1 - 0.0019 17.6 4.3 0.031 13.6 0.2 2.4 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 OAP55475.1 - 0.012 15.9 1.2 2.4 8.4 0.0 2.9 2 1 1 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 OAP55475.1 - 0.024 14.4 0.0 0.053 13.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain MCM PF00493.23 OAP55475.1 - 0.054 12.6 0.0 0.097 11.8 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain FtsK_SpoIIIE PF01580.18 OAP55475.1 - 0.081 12.3 0.0 0.18 11.1 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.23 OAP55475.1 - 0.083 13.0 0.1 5.8 7.0 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OAP55475.1 - 0.11 12.0 0.0 1.2 8.6 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Abhydrolase_1 PF00561.20 OAP55476.1 - 7e-26 91.4 0.1 1.2e-25 90.7 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 OAP55476.1 - 1.4e-12 47.6 0.0 3.5e-12 46.3 0.0 1.7 1 0 0 1 1 1 1 TAP-like protein Hydrolase_4 PF12146.8 OAP55476.1 - 0.037 13.3 0.0 0.24 10.6 0.0 2.0 2 0 0 2 2 2 0 Serine aminopeptidase, S33 MFS_1 PF07690.16 OAP55477.1 - 1e-29 103.6 26.5 1e-29 103.6 26.5 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily DIOX_N PF14226.6 OAP55478.1 - 3.5e-15 56.8 0.1 8.1e-15 55.6 0.0 1.6 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OAP55478.1 - 7.4e-11 42.4 0.0 1.2e-10 41.8 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF4073 PF13285.6 OAP55478.1 - 0.013 15.1 0.1 0.038 13.6 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4073) IDO PF01231.18 OAP55479.1 - 3.3e-165 550.1 0.0 3.8e-165 549.9 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase RcsF PF16358.5 OAP55480.1 - 0.17 11.9 2.9 14 5.8 0.3 2.7 2 0 0 2 2 2 0 RcsF lipoprotein RebB PF11747.8 OAP55480.1 - 0.49 10.5 3.4 2.8 8.1 3.4 2.4 1 0 0 1 1 1 0 Killing trait UEV PF05743.13 OAP55482.1 - 2.4e-38 130.7 0.0 4.6e-38 129.8 0.0 1.5 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.10 OAP55482.1 - 1.3e-15 57.1 0.0 2.4e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 Vps23 core domain UQ_con PF00179.26 OAP55482.1 - 0.016 14.8 0.1 0.047 13.3 0.1 1.8 1 0 0 1 1 1 0 Ubiquitin-conjugating enzyme HAUS-augmin3 PF14932.6 OAP55482.1 - 0.029 14.0 2.2 0.055 13.0 2.2 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 CsbD PF05532.12 OAP55483.1 - 3.5e-12 46.0 19.1 1.2e-10 41.1 6.2 3.3 2 1 1 3 3 3 3 CsbD-like UPF0444 PF15475.6 OAP55483.1 - 0.034 14.4 2.3 0.13 12.6 0.1 2.5 3 0 0 3 3 3 0 Transmembrane protein C12orf23, UPF0444 HET PF06985.11 OAP55485.1 - 1.8e-30 106.2 0.5 3.6e-30 105.2 0.5 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Na_Ca_ex PF01699.24 OAP55486.1 - 6.7e-23 81.3 34.2 1.2e-11 44.8 10.0 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF1774 PF08611.10 OAP55486.1 - 0.49 10.8 4.3 4.4 7.7 0.3 3.1 2 2 0 2 2 2 0 Fungal protein of unknown function (DUF1774) Use1 PF09753.9 OAP55487.1 - 6.8e-09 35.8 1.4 9.4e-09 35.4 1.4 1.3 1 1 0 1 1 1 1 Membrane fusion protein Use1 DUF2105 PF09878.9 OAP55487.1 - 0.078 12.7 0.2 0.12 12.1 0.2 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2105) PhyH PF05721.13 OAP55488.1 - 5.4e-21 75.8 0.2 8.8e-21 75.1 0.2 1.4 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Transp_cyt_pur PF02133.15 OAP55489.1 - 4.7e-82 276.1 43.7 6e-82 275.8 43.7 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Amidohydro_1 PF01979.20 OAP55490.1 - 8.7e-28 97.6 0.0 1.3e-27 97.0 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 OAP55490.1 - 6.7e-15 55.5 0.0 6.1e-08 32.6 0.0 3.0 3 0 0 3 3 3 2 Amidohydrolase family Urease_alpha PF00449.20 OAP55490.1 - 0.12 12.7 0.4 0.12 12.7 0.4 2.1 2 0 0 2 2 2 0 Urease alpha-subunit, N-terminal domain Cu-oxidase_4 PF02578.15 OAP55490.1 - 0.14 11.7 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Multi-copper polyphenol oxidoreductase laccase FAA_hydrolase PF01557.18 OAP55491.1 - 5e-45 153.8 0.1 2.3e-44 151.7 0.0 1.9 2 0 0 2 2 2 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 OAP55491.1 - 3.2e-26 91.6 0.0 7.3e-26 90.5 0.0 1.7 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal Fungal_trans PF04082.18 OAP55491.1 - 1.2e-18 67.2 0.4 2e-18 66.4 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP55493.1 - 1.8e-07 31.2 13.2 3e-07 30.4 13.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAP55493.1 - 0.00014 21.0 0.2 0.0003 19.9 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF1192 PF06698.11 OAP55493.1 - 0.12 12.5 0.2 0.58 10.3 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) MSA-2c PF12238.8 OAP55493.1 - 0.84 9.6 6.6 1.5 8.8 6.6 1.3 1 0 0 1 1 1 0 Merozoite surface antigen 2c ADH_N PF08240.12 OAP55494.1 - 5.3e-31 106.7 0.2 9.3e-31 105.9 0.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAP55494.1 - 1.2e-17 64.1 0.1 2.1e-17 63.3 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 OAP55494.1 - 4.4e-08 32.9 0.2 1.1e-07 31.5 0.2 1.7 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 OAP55494.1 - 7.6e-07 30.2 0.0 1.5e-06 29.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pyr_redox_2 PF07992.14 OAP55494.1 - 0.0069 15.6 0.2 0.018 14.2 0.2 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 OAP55494.1 - 0.024 14.2 0.0 0.036 13.6 0.0 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AlaDh_PNT_C PF01262.21 OAP55494.1 - 0.087 12.1 0.5 0.13 11.5 0.5 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Aminotran_5 PF00266.19 OAP55495.1 - 1.6e-90 303.8 0.0 2e-90 303.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 OAP55495.1 - 1.4e-06 27.8 0.0 2.6e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 OAP55495.1 - 3.7e-05 23.2 0.0 0.00012 21.5 0.0 1.7 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 OAP55495.1 - 0.0049 15.5 0.0 0.0072 14.9 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Pyridoxal_deC PF00282.19 OAP55495.1 - 0.052 12.3 0.0 0.082 11.6 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain BAR PF03114.18 OAP55496.1 - 1.1e-64 218.3 7.5 1.4e-64 218.0 7.5 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 OAP55496.1 - 1.2e-14 53.7 0.1 2.6e-14 52.6 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 OAP55496.1 - 5.6e-11 42.1 0.1 1.1e-10 41.2 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 OAP55496.1 - 7.4e-10 38.4 0.3 2.8e-09 36.5 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain Sec34 PF04136.15 OAP55496.1 - 0.29 11.0 6.3 2.7 7.9 2.0 2.4 2 0 0 2 2 2 0 Sec34-like family APG6_N PF17675.1 OAP55496.1 - 0.48 11.0 12.7 1.8 9.1 6.5 2.4 2 0 0 2 2 2 0 Apg6 coiled-coil region TMPIT PF07851.13 OAP55496.1 - 0.73 9.0 9.5 0.56 9.4 0.5 2.1 1 1 1 2 2 2 0 TMPIT-like protein BRE1 PF08647.11 OAP55496.1 - 0.92 9.6 11.9 0.55 10.3 1.2 2.6 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase Com_YlbF PF06133.11 OAP55496.1 - 3.3 8.4 12.9 5.1 7.7 0.4 2.8 2 1 0 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA MbtH PF03621.13 OAP55497.1 - 0.069 12.6 0.3 1.7 8.1 0.0 2.7 2 0 0 2 2 2 0 MbtH-like protein Urb2 PF10441.9 OAP55498.1 - 7.4e-56 189.3 0.0 7.4e-56 189.3 0.0 3.8 4 1 0 4 4 4 1 Urb2/Npa2 family DUF543 PF04418.12 OAP55499.1 - 3.5e-28 97.4 0.0 4.1e-28 97.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) End3 PF12761.7 OAP55500.1 - 7.2e-67 225.4 1.7 1.1e-66 224.8 1.7 1.3 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_4 PF12763.7 OAP55500.1 - 7.5e-49 164.0 0.0 6.4e-46 154.6 0.1 2.3 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 OAP55500.1 - 8.6e-09 34.3 0.2 2.7e-07 29.6 0.2 2.6 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 OAP55500.1 - 3.7e-08 33.7 0.7 2.5e-06 27.8 0.0 3.2 3 1 1 4 4 4 1 EF-hand domain pair EF-hand_8 PF13833.6 OAP55500.1 - 4.3e-06 26.5 0.1 0.0032 17.3 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OAP55500.1 - 1e-05 25.1 0.4 0.00044 19.9 0.2 3.1 3 0 0 3 3 3 1 EF-hand domain EF-hand_5 PF13202.6 OAP55500.1 - 0.0036 16.7 0.2 0.0096 15.4 0.2 1.7 1 0 0 1 1 1 1 EF hand CENP-F_leu_zip PF10473.9 OAP55500.1 - 1.4 9.0 12.1 0.061 13.4 3.6 2.5 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4407 PF14362.6 OAP55500.1 - 2.4 7.4 5.1 3.8 6.8 5.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) WBP-1 PF11669.8 OAP55501.1 - 0.00088 19.9 0.3 0.0012 19.5 0.3 1.2 1 0 0 1 1 1 1 WW domain-binding protein 1 Amnionless PF14828.6 OAP55501.1 - 0.053 12.4 0.0 0.064 12.1 0.0 1.2 1 0 0 1 1 1 0 Amnionless CD34_antigen PF06365.12 OAP55501.1 - 0.14 11.7 0.0 0.16 11.6 0.0 1.1 1 0 0 1 1 1 0 CD34/Podocalyxin family HhH-GPD PF00730.25 OAP55502.1 - 2.1e-14 53.9 0.0 4.2e-14 52.9 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 OAP55502.1 - 4e-07 29.6 0.0 8.6e-07 28.5 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif UQ_con PF00179.26 OAP55503.1 - 2.1e-37 127.9 0.0 2.3e-37 127.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OAP55503.1 - 0.004 16.9 0.0 0.0063 16.2 0.0 1.3 1 1 0 1 1 1 1 Prokaryotic E2 family B Proteasome PF00227.26 OAP55504.1 - 2.3e-57 193.6 0.0 5.6e-33 114.0 0.0 2.2 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.9 OAP55504.1 - 9.3e-11 41.2 0.1 3.1e-10 39.5 0.0 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature TPR_1 PF00515.28 OAP55506.1 - 3.4e-54 178.6 33.9 2.8e-08 33.2 0.0 10.9 11 1 0 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.17 OAP55506.1 - 7.2e-48 156.9 25.8 1.2e-06 28.1 0.1 10.5 11 0 0 11 11 11 8 Tetratricopeptide repeat TPR_8 PF13181.6 OAP55506.1 - 6e-41 135.3 22.2 2.2e-08 33.7 0.0 10.8 10 1 0 10 10 10 8 Tetratricopeptide repeat TPR_16 PF13432.6 OAP55506.1 - 4.7e-29 100.8 6.9 1.8e-05 25.3 0.1 6.4 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_19 PF14559.6 OAP55506.1 - 7.3e-27 93.7 14.5 1.5e-06 28.6 0.2 7.2 5 2 2 7 7 7 5 Tetratricopeptide repeat TPR_14 PF13428.6 OAP55506.1 - 2.5e-25 87.0 16.4 7.7e-06 26.3 0.1 9.0 3 3 7 10 10 10 7 Tetratricopeptide repeat TPR_17 PF13431.6 OAP55506.1 - 3e-24 83.6 22.9 0.00098 19.3 0.1 10.1 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_12 PF13424.6 OAP55506.1 - 1e-23 83.4 24.1 3.7e-05 23.9 0.1 8.1 4 2 3 7 7 7 5 Tetratricopeptide repeat TPR_11 PF13414.6 OAP55506.1 - 4.3e-23 80.7 30.6 2e-05 24.2 0.1 9.5 5 2 4 9 9 9 6 TPR repeat TPR_6 PF13174.6 OAP55506.1 - 1.6e-19 69.1 20.2 0.00072 20.0 0.0 9.6 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_7 PF13176.6 OAP55506.1 - 2e-17 61.8 17.1 0.047 13.7 0.0 9.5 9 1 0 9 9 9 5 Tetratricopeptide repeat TPR_9 PF13371.6 OAP55506.1 - 1.2e-16 60.6 12.4 0.00074 19.6 0.1 6.8 1 1 7 8 8 8 7 Tetratricopeptide repeat ANAPC3 PF12895.7 OAP55506.1 - 2.7e-12 46.7 12.9 1.4e-06 28.5 1.7 3.5 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 OAP55506.1 - 2.5e-09 36.8 15.0 0.025 13.8 0.1 5.2 1 1 3 5 5 5 4 Tetratricopeptide repeat TPR_21 PF09976.9 OAP55506.1 - 6.5e-08 32.5 8.1 0.032 13.9 0.0 4.2 4 2 1 5 5 4 3 Tetratricopeptide repeat-like domain BTAD PF03704.17 OAP55506.1 - 7.8e-05 23.1 10.3 0.026 14.9 0.4 3.8 3 1 0 3 3 3 1 Bacterial transcriptional activator domain Fis1_TPR_C PF14853.6 OAP55506.1 - 0.00011 22.2 0.7 0.2 11.8 0.0 4.3 4 0 0 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat ChAPs PF09295.10 OAP55506.1 - 0.0083 15.2 6.4 0.81 8.6 0.4 3.4 3 1 1 4 4 4 2 ChAPs (Chs5p-Arf1p-binding proteins) DUF2225 PF09986.9 OAP55506.1 - 0.028 14.1 4.7 2.8 7.6 0.2 3.4 2 2 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) DUF410 PF04190.13 OAP55506.1 - 0.4 10.4 4.7 6.7 6.4 0.5 3.2 1 1 0 2 2 2 0 Protein of unknown function (DUF410) TPR_20 PF14561.6 OAP55506.1 - 2.4 8.6 11.0 1.6 9.1 0.0 4.9 5 1 1 6 6 6 0 Tetratricopeptide repeat Ribosomal_L3 PF00297.22 OAP55507.1 - 3e-161 536.5 9.9 3.4e-161 536.3 9.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 NuiA PF07924.11 OAP55508.1 - 0.00016 22.0 0.3 0.39 11.1 0.0 2.2 1 1 1 2 2 2 2 Nuclease A inhibitor-like protein SKN1 PF03935.15 OAP55509.1 - 1.7e-231 768.9 0.8 2e-231 768.7 0.8 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) NUC173 PF08161.12 OAP55511.1 - 6.1e-76 254.6 0.0 1.5e-73 246.8 0.0 3.8 4 0 0 4 4 4 1 NUC173 domain HEAT PF02985.22 OAP55511.1 - 2e-05 24.4 1.5 0.36 11.2 0.0 5.1 4 0 0 4 4 4 2 HEAT repeat Nipped-B_C PF12830.7 OAP55511.1 - 0.019 14.9 0.8 0.081 12.9 0.0 2.5 3 0 0 3 3 3 0 Sister chromatid cohesion C-terminus HEAT_2 PF13646.6 OAP55511.1 - 0.14 12.6 3.5 3.7 8.0 0.3 4.5 5 0 0 5 5 5 0 HEAT repeats NAD_binding_10 PF13460.6 OAP55512.1 - 7.3e-13 48.8 0.0 9.7e-13 48.4 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 OAP55512.1 - 3.1e-07 30.2 0.0 5.6e-07 29.3 0.0 1.4 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 OAP55512.1 - 0.0023 17.4 0.1 0.046 13.2 0.0 2.5 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 OAP55512.1 - 0.0094 16.2 0.0 0.029 14.6 0.0 1.8 1 1 0 1 1 1 1 TrkA-N domain 3Beta_HSD PF01073.19 OAP55512.1 - 0.039 13.0 0.0 0.067 12.2 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.17 OAP55512.1 - 0.048 14.3 0.0 0.1 13.2 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent HET PF06985.11 OAP55513.1 - 7.4e-25 88.0 0.2 1.4e-24 87.1 0.2 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ribosomal_L21p PF00829.21 OAP55514.1 - 5.2e-07 29.9 0.1 7.7e-07 29.3 0.1 1.2 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein DUF2415 PF10313.9 OAP55515.1 - 7.4e-13 48.2 0.0 1.6e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) WD40 PF00400.32 OAP55515.1 - 0.00018 22.3 1.1 1.9 9.5 0.0 5.0 5 0 0 5 5 5 2 WD domain, G-beta repeat HSP70 PF00012.20 OAP55516.1 - 1.2e-270 899.0 17.1 1.3e-270 898.8 17.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 OAP55516.1 - 6.1e-14 51.6 10.8 7.8e-13 47.9 3.9 3.1 3 0 0 3 3 3 2 MreB/Mbl protein FGGY_C PF02782.16 OAP55516.1 - 9.5e-05 22.2 0.3 0.00032 20.5 0.1 1.9 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain DUF4363 PF14276.6 OAP55516.1 - 0.21 11.7 6.2 0.43 10.7 6.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4363) Med9 PF07544.13 OAP55516.1 - 0.3 11.2 6.6 0.23 11.6 1.5 2.9 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 RRN3 PF05327.11 OAP55516.1 - 0.43 9.1 5.1 0.65 8.5 5.1 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 FtsA PF14450.6 OAP55516.1 - 1.1 9.7 11.1 2.6 8.5 0.5 4.2 3 3 0 3 3 3 0 Cell division protein FtsA Rab5ip PF07019.12 OAP55518.1 - 2.6e-23 82.4 3.2 3.3e-23 82.1 3.2 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) SAM_2 PF07647.17 OAP55519.1 - 2.6e-08 33.9 0.1 2e-06 27.8 0.1 2.4 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 OAP55519.1 - 0.00024 21.5 0.1 0.00055 20.3 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) His_Phos_1 PF00300.22 OAP55520.1 - 6.9e-08 32.4 0.0 1.1e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) adh_short PF00106.25 OAP55522.1 - 6.1e-20 71.5 0.3 4.2e-17 62.3 0.1 2.6 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAP55522.1 - 1.2e-12 47.9 0.1 9.8e-10 38.4 0.0 2.4 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP55522.1 - 7.6e-11 42.2 0.1 1.7e-10 41.1 0.0 1.6 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 OAP55522.1 - 0.0094 15.1 0.0 0.016 14.4 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 OAP55522.1 - 0.021 14.0 0.1 0.18 10.9 0.1 2.0 1 1 0 1 1 1 0 Male sterility protein LSM PF01423.22 OAP55523.1 - 1.6e-13 50.1 0.0 2.5e-13 49.5 0.0 1.3 1 0 0 1 1 1 1 LSM domain DUF5605 PF18310.1 OAP55524.1 - 0.21 11.5 0.9 3.5 7.6 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5605) BCDHK_Adom3 PF10436.9 OAP55525.1 - 2.2e-74 248.7 0.0 3.2e-74 248.2 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 OAP55525.1 - 2.1e-12 47.6 0.0 4.1e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 OAP55525.1 - 0.044 13.6 0.0 0.085 12.7 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase IBP39 PF11422.8 OAP55526.1 - 0.078 12.7 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Initiator binding protein 39 kDa SnoaL PF07366.12 OAP55527.1 - 4.2e-22 78.3 0.0 5.2e-22 78.0 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 OAP55527.1 - 9.2e-13 48.7 0.0 1.2e-12 48.4 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF1754 PF08555.10 OAP55528.1 - 5.6e-13 49.5 22.4 4e-12 46.8 22.4 2.0 1 1 0 1 1 1 1 Eukaryotic family of unknown function (DUF1754) UcrQ PF02939.16 OAP55529.1 - 2.5e-34 117.0 0.1 3e-34 116.8 0.1 1.1 1 0 0 1 1 1 1 UcrQ family Band_7 PF01145.25 OAP55530.1 - 5e-25 88.5 10.3 5.8e-25 88.3 9.0 1.7 1 1 1 2 2 2 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 OAP55530.1 - 0.0045 16.1 5.2 0.0066 15.6 5.2 1.3 1 0 0 1 1 1 1 SigmaW regulon antibacterial WSC PF01822.19 OAP55531.1 - 1e-18 67.3 9.5 1.4e-18 66.8 9.5 1.2 1 0 0 1 1 1 1 WSC domain DUF1996 PF09362.10 OAP55532.1 - 3.5e-89 298.8 1.4 4.8e-89 298.4 1.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) WSC PF01822.19 OAP55532.1 - 4.7e-18 65.2 11.4 4.7e-18 65.2 11.4 2.5 3 0 0 3 3 3 1 WSC domain BRCT PF00533.26 OAP55533.1 - 1.7e-07 31.5 0.0 4.2e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 OAP55533.1 - 4.5e-05 23.3 0.0 9.1e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_2 PF16589.5 OAP55533.1 - 0.0024 18.2 0.0 0.0067 16.8 0.0 1.7 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain STE2 PF02116.15 OAP55534.1 - 3.6e-18 65.9 18.0 5.2e-18 65.3 18.0 1.1 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR DUF4724 PF15852.5 OAP55534.1 - 0.097 13.2 0.1 0.22 12.0 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4724) AOX PF01786.17 OAP55534.1 - 0.12 11.9 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Alternative oxidase DUF5134 PF17197.4 OAP55534.1 - 3.2 7.6 7.8 13 5.7 7.8 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF5134) Pex24p PF06398.11 OAP55535.1 - 8.5e-87 291.5 0.1 1.1e-86 291.2 0.1 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF3292 PF11696.8 OAP55535.1 - 0.013 13.9 7.9 0.09 11.1 2.6 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3292) 2TM PF13239.6 OAP55535.1 - 0.046 14.0 0.3 0.15 12.4 0.3 1.8 1 0 0 1 1 1 0 2TM domain Rod_cone_degen PF15201.6 OAP55535.1 - 0.14 12.3 0.3 1.1 9.4 0.0 2.7 2 0 0 2 2 2 0 Progressive rod-cone degeneration Pkinase PF00069.25 OAP55536.1 - 6.5e-53 179.8 0.0 9.4e-53 179.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP55536.1 - 7.7e-19 68.0 0.3 1.4e-18 67.1 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 OAP55536.1 - 0.08 12.9 0.1 0.08 12.9 0.1 2.2 2 1 1 3 3 3 0 Phosphotransferase enzyme family RIO1 PF01163.22 OAP55536.1 - 0.17 11.5 0.1 0.31 10.6 0.1 1.4 1 0 0 1 1 1 0 RIO1 family Ank_2 PF12796.7 OAP55538.1 - 3e-22 79.0 0.2 1e-09 38.8 0.0 3.4 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OAP55538.1 - 4.5e-12 45.0 1.6 0.00019 21.6 0.0 4.7 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 OAP55538.1 - 2.9e-11 43.7 0.2 3.8e-08 33.7 0.0 3.8 1 1 4 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 OAP55538.1 - 8e-09 35.6 2.7 0.0049 17.3 0.1 4.2 4 1 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 OAP55538.1 - 8e-07 29.2 2.0 0.011 16.0 0.0 4.0 1 1 4 5 5 5 3 Ankyrin repeats (many copies) Zn_clus PF00172.18 OAP55538.1 - 5.7 7.1 15.7 10 6.4 15.7 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1229 PF06797.11 OAP55539.1 - 0.22 11.7 0.0 0.38 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1229) Asp PF00026.23 OAP55540.1 - 1.3e-31 110.2 0.2 4.7e-31 108.4 0.2 1.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease adh_short PF00106.25 OAP55541.1 - 2.6e-31 108.6 0.0 3.5e-31 108.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP55541.1 - 9.7e-21 74.4 0.0 1.4e-19 70.6 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP55541.1 - 1.9e-11 44.2 0.0 3.2e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAP55541.1 - 3.5e-09 36.5 0.0 3.1e-06 26.9 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 OAP55541.1 - 2.6e-06 26.8 0.0 3.6e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 OAP55541.1 - 2.1e-05 24.1 0.0 0.00013 21.5 0.0 1.9 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 OAP55541.1 - 0.00056 19.0 0.0 0.00074 18.6 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family 3HCDH_N PF02737.18 OAP55541.1 - 0.0015 18.4 0.1 0.0025 17.7 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.17 OAP55541.1 - 0.0036 16.4 0.1 0.0065 15.6 0.1 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain ThiF PF00899.21 OAP55541.1 - 0.017 14.5 0.1 0.034 13.5 0.1 1.4 1 0 0 1 1 1 0 ThiF family DapB_N PF01113.20 OAP55541.1 - 0.033 14.3 0.1 0.053 13.6 0.1 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus ELFV_dehydrog PF00208.21 OAP55541.1 - 0.039 13.7 0.0 0.057 13.1 0.0 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Ldh_1_N PF00056.23 OAP55541.1 - 0.04 14.0 0.0 0.064 13.4 0.0 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain adh_short_C2 PF13561.6 OAP55542.1 - 8.3e-50 169.5 0.3 4.6e-29 101.6 0.0 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP55542.1 - 1.3e-33 116.2 0.3 1.3e-20 73.7 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 OAP55542.1 - 5.5e-08 32.9 0.1 2e-07 31.1 0.0 1.8 2 0 0 2 2 2 1 KR domain 3Beta_HSD PF01073.19 OAP55542.1 - 0.0062 15.6 0.1 0.013 14.5 0.1 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 OAP55542.1 - 0.066 12.7 0.0 1.5 8.3 0.0 2.2 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Fungal_trans PF04082.18 OAP55543.1 - 2.3e-28 99.0 0.7 4e-28 98.2 0.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP55543.1 - 3.2e-06 27.2 19.1 5.3e-06 26.5 19.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AP_endonuc_2 PF01261.24 OAP55544.1 - 9.9e-29 100.3 0.1 1.3e-28 99.9 0.1 1.1 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Sugar_tr PF00083.24 OAP55545.1 - 4e-61 207.2 20.6 4.5e-61 207.1 20.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP55545.1 - 6.8e-22 77.9 47.9 1.5e-19 70.2 23.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 OAP55545.1 - 0.0034 15.9 1.2 0.0034 15.9 1.2 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) TetR_C_7 PF14246.6 OAP55546.1 - 0.13 12.3 0.0 0.17 11.9 0.0 1.2 1 0 0 1 1 1 0 AefR-like transcriptional repressor, C-terminal domain DUF3439 PF11921.8 OAP55547.1 - 0.11 12.5 4.9 0.39 10.7 4.9 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) zf-BED PF02892.15 OAP55547.1 - 0.17 12.0 3.1 2.7 8.1 0.2 2.5 2 0 0 2 2 2 0 BED zinc finger Cnd3 PF12719.7 OAP55548.1 - 2.3e-43 148.5 1.5 7.3e-42 143.6 0.0 3.0 3 1 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 OAP55548.1 - 3.9e-08 33.6 11.2 0.00015 22.1 2.6 4.9 4 1 1 5 5 5 2 HEAT repeats HEAT PF02985.22 OAP55548.1 - 1.2e-05 25.1 12.3 0.04 14.2 0.0 7.1 7 0 0 7 7 7 2 HEAT repeat Cnd1 PF12717.7 OAP55548.1 - 0.00093 19.3 0.4 0.092 12.8 0.5 3.7 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 OAP55548.1 - 0.0082 16.6 11.6 0.045 14.3 0.7 5.6 6 0 0 6 6 6 1 HEAT-like repeat DUF3449 PF11931.8 OAP55549.1 - 7.8e-72 240.9 0.0 2e-71 239.6 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3449) SF3A3 PF16837.5 OAP55549.1 - 3.7e-26 91.4 0.8 1.1e-25 90.0 0.2 2.0 2 0 0 2 2 2 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 SF3a60_bindingd PF12108.8 OAP55549.1 - 1.8e-14 53.3 1.2 4e-14 52.2 1.2 1.6 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-met PF12874.7 OAP55549.1 - 2.3e-09 37.3 2.2 9.6e-08 32.2 0.3 2.4 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 OAP55549.1 - 4.9e-07 29.9 0.4 4.9e-07 29.9 0.4 2.8 2 1 0 2 2 2 1 Zinc-finger double-stranded RNA-binding PRP9_N PF16958.5 OAP55549.1 - 0.00024 21.2 10.7 0.032 14.2 0.7 2.8 2 1 1 3 3 3 2 Pre-mRNA-splicing factor PRP9 N-terminus zf-C2H2_2 PF12756.7 OAP55549.1 - 0.0011 19.2 0.5 0.045 14.1 0.0 2.9 3 0 0 3 3 3 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 OAP55549.1 - 0.043 14.7 1.5 2.3 9.3 0.1 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 OAP55549.1 - 1.4 9.5 4.4 1.9 9.1 0.5 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type Arrestin_N PF00339.29 OAP55550.1 - 1.5e-08 34.8 0.0 5.9e-08 32.9 0.0 1.9 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain RFC1 PF08519.12 OAP55551.1 - 2.1e-59 200.2 0.0 1.1e-58 197.8 0.0 2.1 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain BRCT PF00533.26 OAP55551.1 - 2.5e-14 53.4 0.0 7.6e-14 51.8 0.0 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.29 OAP55551.1 - 7.3e-10 39.4 0.0 2e-09 37.9 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 OAP55551.1 - 1.8e-06 28.0 0.0 4.1e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 OAP55551.1 - 0.00011 22.5 0.0 0.00049 20.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 OAP55551.1 - 0.00094 19.4 0.1 0.0036 17.5 0.1 2.0 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OAP55551.1 - 0.0051 17.2 2.2 0.006 17.0 0.1 2.2 2 1 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 OAP55551.1 - 0.01 15.5 0.1 0.01 15.5 0.1 1.9 2 0 0 2 2 1 0 AAA domain RuvB_N PF05496.12 OAP55551.1 - 0.011 15.5 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain PTCB-BRCT PF12738.7 OAP55551.1 - 0.016 15.1 0.0 0.038 13.9 0.0 1.7 1 0 0 1 1 1 0 twin BRCT domain AAA_18 PF13238.6 OAP55551.1 - 0.018 15.6 0.1 0.018 15.6 0.1 2.4 2 0 0 2 2 1 0 AAA domain NACHT PF05729.12 OAP55551.1 - 0.026 14.4 0.0 5.8 6.8 0.0 2.5 2 0 0 2 2 2 0 NACHT domain AAA_14 PF13173.6 OAP55551.1 - 0.1 12.6 0.0 0.26 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 OAP55551.1 - 0.13 12.2 0.0 0.38 10.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 OAP55551.1 - 1.2 9.4 4.3 0.54 10.5 0.1 2.5 2 0 0 2 2 2 0 AAA domain DUF3112 PF11309.8 OAP55552.1 - 7.6e-12 45.2 3.5 9.9e-06 25.2 0.0 2.5 1 1 1 2 2 2 2 Protein of unknown function (DUF3112) Zn_clus PF00172.18 OAP55553.1 - 1.9e-05 24.7 10.4 3.1e-05 24.0 10.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aa_trans PF01490.18 OAP55554.1 - 4.8e-26 91.4 32.9 7e-26 90.9 32.9 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Cecropin PF00272.19 OAP55554.1 - 0.32 10.7 0.9 0.71 9.6 0.9 1.5 1 0 0 1 1 1 0 Cecropin family HRI1 PF16815.5 OAP55555.1 - 3.3e-31 108.8 0.4 4.3e-31 108.4 0.4 1.1 1 0 0 1 1 1 1 Protein HRI1 LamB_YcsF PF03746.16 OAP55556.1 - 1e-69 234.9 0.0 1.7e-69 234.1 0.0 1.3 1 0 0 1 1 1 1 LamB/YcsF family Amidase PF01425.21 OAP55557.1 - 6.9e-95 318.6 0.1 8e-95 318.4 0.1 1.0 1 0 0 1 1 1 1 Amidase Ribosomal_L16 PF00252.18 OAP55558.1 - 7.9e-32 110.0 0.0 1.1e-31 109.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e ORC_WH_C PF18137.1 OAP55559.1 - 0.2 11.7 1.4 0.29 11.2 1.4 1.5 1 1 0 1 1 1 0 Origin recognition complex winged helix C-terminal Gly_transf_sug PF04488.15 OAP55561.1 - 4.3e-09 36.9 0.0 3.2e-08 34.1 0.0 2.3 2 1 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 OAP55561.1 - 0.022 14.1 0.0 0.031 13.6 0.0 1.1 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain CtaG_Cox11 PF04442.14 OAP55562.1 - 4.3e-62 208.6 0.0 5.1e-62 208.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 Redoxin PF08534.10 OAP55563.1 - 9.1e-15 54.6 0.0 1e-14 54.5 0.0 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 OAP55563.1 - 1.2e-10 41.4 0.0 2.6e-08 33.8 0.0 2.1 2 0 0 2 2 2 2 AhpC/TSA family Pro-kuma_activ PF09286.11 OAP55564.1 - 1.2e-39 135.9 1.4 2.1e-39 135.0 0.1 2.1 3 0 0 3 3 3 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 OAP55564.1 - 2e-06 27.3 0.2 6.8e-05 22.3 0.1 2.4 2 1 0 2 2 2 2 Subtilase family TMEM135_C_rich PF15982.5 OAP55565.1 - 0.00024 21.7 0.1 0.00075 20.1 0.1 1.8 1 1 0 1 1 1 1 N-terminal cysteine-rich region of Transmembrane protein 135 FOLN PF09289.10 OAP55565.1 - 0.012 15.8 1.2 0.02 15.1 1.2 1.3 1 0 0 1 1 1 0 Follistatin/Osteonectin-like EGF domain Cation_ATPase_C PF00689.21 OAP55565.1 - 0.03 14.1 0.1 0.43 10.3 0.1 2.2 1 1 0 2 2 2 0 Cation transporting ATPase, C-terminus Trp_oprn_chp PF09534.10 OAP55565.1 - 0.038 13.8 0.1 0.078 12.8 0.1 1.5 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF2863 PF11062.8 OAP55565.1 - 0.19 10.1 0.0 0.28 9.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2863) Fungal_trans PF04082.18 OAP55566.1 - 6.8e-11 41.7 0.6 1.5e-10 40.6 0.6 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 OAP55566.1 - 2.2e-07 31.0 9.6 6.8e-05 23.1 2.9 3.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 OAP55566.1 - 2.5e-06 27.6 0.5 0.056 13.7 0.0 2.7 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 OAP55566.1 - 7.8e-05 23.2 10.1 0.014 16.1 1.5 3.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OAP55566.1 - 0.00061 20.1 0.9 0.00061 20.1 0.9 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-met PF12874.7 OAP55566.1 - 0.002 18.4 3.1 0.88 10.0 0.1 3.0 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-Di19 PF05605.12 OAP55566.1 - 0.23 11.8 3.3 0.91 9.9 3.3 2.0 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding GAGA PF09237.11 OAP55566.1 - 0.49 10.2 3.6 0.99 9.3 1.1 2.3 1 1 1 2 2 2 0 GAGA factor zf-MYST PF17772.1 OAP55566.1 - 0.57 9.8 4.2 3.4 7.4 0.3 3.2 3 0 0 3 3 3 0 MYST family zinc finger domain zf-C2HC_2 PF13913.6 OAP55566.1 - 3.4 7.7 4.9 14 5.7 0.4 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type p450 PF00067.22 OAP55567.1 - 5.6e-72 243.0 0.0 6.6e-72 242.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FlbT PF07378.11 OAP55567.1 - 0.1 12.6 0.0 0.26 11.4 0.0 1.6 1 0 0 1 1 1 0 Flagellar protein FlbT DUF1593 PF07632.11 OAP55567.1 - 0.16 11.3 0.1 0.4 10.1 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1593) SirB PF04247.12 OAP55568.1 - 0.049 13.7 0.1 1.7 8.7 0.0 2.4 2 0 0 2 2 2 0 Invasion gene expression up-regulator, SirB Acyl-CoA_dh_N PF02771.16 OAP55569.1 - 3.3e-20 72.9 0.2 2.3e-19 70.1 0.0 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 OAP55569.1 - 3.8e-20 72.6 1.6 6.1e-20 72.0 1.6 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 OAP55569.1 - 4.3e-05 23.6 0.0 0.00012 22.2 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Gpr1_Fun34_YaaH PF01184.19 OAP55570.1 - 8.8e-30 103.9 15.4 1.1e-29 103.6 15.4 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF1700 PF08006.11 OAP55570.1 - 0.59 9.7 3.7 1.1 8.8 3.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) DUF4714 PF15833.5 OAP55570.1 - 1.9 8.4 4.0 3.1 7.8 4.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4714) MFS_1 PF07690.16 OAP55571.1 - 4.7e-28 98.1 25.3 4.7e-28 98.1 25.3 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 OAP55571.1 - 0.0001 21.7 13.3 0.00014 21.3 6.3 2.3 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB DUF4064 PF13273.6 OAP55571.1 - 1.2 9.4 14.5 0.3 11.4 0.4 4.2 3 1 0 3 3 3 0 Protein of unknown function (DUF4064) DIOX_N PF14226.6 OAP55572.1 - 3.6e-32 111.6 0.0 5.8e-32 110.9 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OAP55572.1 - 6.2e-22 78.0 0.0 1.1e-21 77.3 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TPR_12 PF13424.6 OAP55574.1 - 2e-06 28.0 0.2 0.0029 17.8 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 OAP55574.1 - 4e-05 23.4 0.6 0.00079 19.4 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 OAP55574.1 - 0.00011 21.9 0.5 0.0023 17.7 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 OAP55574.1 - 0.00024 21.6 0.0 0.0048 17.4 0.0 2.8 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 OAP55574.1 - 0.00037 20.3 0.1 0.022 14.7 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 OAP55574.1 - 0.0012 18.6 0.4 0.011 15.6 0.1 2.6 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 OAP55574.1 - 0.0074 16.4 1.2 0.034 14.3 0.0 2.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 OAP55574.1 - 0.014 16.2 3.1 0.15 13.0 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 OAP55574.1 - 0.017 14.8 0.0 0.064 12.9 0.0 2.0 2 0 0 2 2 2 0 TPR repeat ANAPC3 PF12895.7 OAP55574.1 - 0.051 13.8 0.0 0.34 11.2 0.0 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 OAP55574.1 - 0.074 13.7 1.2 1.2 9.9 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 OAP55574.1 - 0.09 13.0 0.0 0.33 11.3 0.0 2.0 2 0 0 2 2 1 0 Tetratricopeptide repeat DUF4763 PF15960.5 OAP55575.1 - 0.16 11.3 0.0 0.16 11.3 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4763) PBP PF01161.20 OAP55576.1 - 7.6e-20 71.6 0.1 1.1e-19 71.0 0.1 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Dynamin_M PF01031.20 OAP55577.1 - 3e-110 368.0 0.0 5.6e-110 367.0 0.0 1.5 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 OAP55577.1 - 1.4e-56 191.2 0.3 2.9e-56 190.1 0.0 1.7 2 0 0 2 2 2 1 Dynamin family GED PF02212.18 OAP55577.1 - 1.5e-32 111.6 0.7 4e-32 110.2 0.7 1.8 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 OAP55577.1 - 0.00012 22.1 0.3 0.0021 18.1 0.3 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF5130 PF17174.4 OAP55577.1 - 0.03 14.5 0.4 1.8 8.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5130) DLIC PF05783.11 OAP55577.1 - 0.54 9.0 2.0 7.5 5.3 2.8 1.9 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) BRO1 PF03097.18 OAP55579.1 - 2.1e-05 23.5 0.0 4.1e-05 22.6 0.0 1.4 1 1 0 1 1 1 1 BRO1-like domain HBM PF16591.5 OAP55579.1 - 0.097 12.1 0.1 11 5.3 0.1 2.6 3 0 0 3 3 3 0 Helical bimodular sensor domain GFA PF04828.14 OAP55580.1 - 3.5e-11 43.3 0.1 3.5e-11 43.3 0.1 1.6 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme F-box-like PF12937.7 OAP55583.1 - 0.005 16.7 0.0 0.0098 15.8 0.0 1.5 1 0 0 1 1 1 1 F-box-like Ofd1_CTDD PF10637.9 OAP55586.1 - 3.6e-86 288.7 0.0 1e-80 270.8 0.0 2.2 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 OAP55586.1 - 2e-22 79.7 0.0 6.1e-22 78.1 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 OAP55586.1 - 3.5e-13 50.3 0.0 8.2e-13 49.1 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Cupin_2 PF07883.11 OAP55587.1 - 2.5e-10 39.9 0.3 5.2e-10 38.9 0.3 1.5 1 1 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 OAP55587.1 - 8.5e-07 28.7 0.0 1.2e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.19 OAP55587.1 - 0.14 12.1 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 AraC-like ligand binding domain ABC_tran PF00005.27 OAP55588.1 - 4.5e-46 156.8 0.2 7.1e-22 78.4 0.0 3.0 4 0 0 4 4 2 2 ABC transporter ABC_tran_Xtn PF12848.7 OAP55588.1 - 3e-21 75.2 4.3 3e-21 75.2 4.3 3.4 4 0 0 4 4 4 1 ABC transporter AAA_21 PF13304.6 OAP55588.1 - 5.7e-19 69.0 0.3 0.00032 20.6 0.0 4.3 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OAP55588.1 - 4e-10 39.5 0.3 0.26 10.7 0.1 4.3 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_18 PF13238.6 OAP55588.1 - 1.9e-08 34.9 1.0 0.093 13.3 0.0 4.0 4 0 0 4 4 4 3 AAA domain AAA_29 PF13555.6 OAP55588.1 - 8.7e-08 31.8 0.2 0.0085 15.8 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.6 OAP55588.1 - 1.4e-07 31.5 0.0 0.0089 15.8 0.0 2.9 2 1 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 OAP55588.1 - 2.4e-06 27.5 0.1 0.0056 16.6 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 OAP55588.1 - 1e-05 26.0 0.0 0.05 14.0 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 OAP55588.1 - 2.5e-05 24.3 0.0 0.03 14.4 0.1 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase NB-ARC PF00931.22 OAP55588.1 - 9.2e-05 21.7 0.1 0.19 10.9 0.0 3.2 3 0 0 3 3 3 1 NB-ARC domain AAA_23 PF13476.6 OAP55588.1 - 9.3e-05 23.0 11.4 0.029 14.9 0.1 3.9 5 0 0 5 5 3 2 AAA domain AAA_22 PF13401.6 OAP55588.1 - 0.00013 22.2 0.1 0.23 11.7 0.0 2.8 2 1 0 2 2 2 2 AAA domain NACHT PF05729.12 OAP55588.1 - 0.00021 21.3 0.1 0.73 9.7 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA PF00004.29 OAP55588.1 - 0.00027 21.4 0.1 0.87 10.0 0.0 3.2 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 OAP55588.1 - 0.00051 20.3 0.1 0.27 11.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 OAP55588.1 - 0.00077 19.5 0.1 2 8.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 OAP55588.1 - 0.0014 19.0 0.6 2.7 8.4 0.0 3.0 3 0 0 3 3 2 1 RNA helicase AAA_24 PF13479.6 OAP55588.1 - 0.0017 18.1 0.3 0.96 9.1 0.0 3.0 3 0 0 3 3 3 1 AAA domain Roc PF08477.13 OAP55588.1 - 0.002 18.3 0.1 2.5 8.3 0.2 3.0 2 1 1 3 3 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_33 PF13671.6 OAP55588.1 - 0.0025 18.0 0.2 0.87 9.7 0.1 2.9 3 0 0 3 3 2 1 AAA domain AAA_27 PF13514.6 OAP55588.1 - 0.0027 17.3 0.0 1.2 8.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain DUF2813 PF11398.8 OAP55588.1 - 0.0068 15.7 0.0 4.3 6.5 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2813) MCM PF00493.23 OAP55588.1 - 0.017 14.2 0.1 4.6 6.3 0.0 2.3 2 0 0 2 2 2 0 MCM P-loop domain AAA_14 PF13173.6 OAP55588.1 - 0.02 14.9 0.0 7.1 6.7 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 OAP55588.1 - 0.032 14.7 0.0 6.1 7.3 0.0 3.0 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 OAP55588.1 - 0.033 14.1 0.0 9.8 6.0 0.0 2.5 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_30 PF13604.6 OAP55588.1 - 0.033 13.9 0.2 2.6 7.7 0.1 2.9 2 1 0 2 2 2 0 AAA domain AAA_7 PF12775.7 OAP55588.1 - 0.037 13.6 0.0 1.1 8.8 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region PduV-EutP PF10662.9 OAP55588.1 - 0.051 13.3 0.6 3.7 7.3 0.0 3.0 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation ABC_ATPase PF09818.9 OAP55588.1 - 0.058 12.2 0.0 14 4.3 0.0 3.2 3 1 1 4 4 4 0 Predicted ATPase of the ABC class AAA_25 PF13481.6 OAP55588.1 - 0.062 12.9 0.0 2.8 7.5 0.0 3.1 3 0 0 3 3 3 0 AAA domain DUF815 PF05673.13 OAP55588.1 - 0.062 12.5 0.1 5.7 6.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NTPase_1 PF03266.15 OAP55588.1 - 0.073 13.0 0.2 2.7 7.9 0.1 2.6 2 0 0 2 2 2 0 NTPase FeoB_N PF02421.18 OAP55588.1 - 0.084 12.4 0.3 5.7 6.5 0.0 3.0 3 0 0 3 3 3 0 Ferrous iron transport protein B DAP3 PF10236.9 OAP55588.1 - 0.088 12.0 0.4 13 4.9 0.0 2.7 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 ATPase_2 PF01637.18 OAP55588.1 - 0.094 12.6 0.2 15 5.4 0.0 2.8 3 0 0 3 3 2 0 ATPase domain predominantly from Archaea Phage_tail_2 PF06199.11 OAP55588.1 - 0.1 12.7 0.0 0.33 11.0 0.0 1.8 1 0 0 1 1 1 0 Phage tail tube protein MeaB PF03308.16 OAP55588.1 - 0.14 11.1 0.2 12 4.8 0.0 2.6 2 1 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 OAP55588.1 - 0.22 11.6 1.4 48 4.0 0.0 3.6 3 1 1 4 4 4 0 Dynamin family DUF87 PF01935.17 OAP55588.1 - 0.23 11.5 2.7 20 5.2 0.0 3.4 3 1 1 4 4 3 0 Helicase HerA, central domain Sugar_tr PF00083.24 OAP55590.1 - 2.9e-83 280.2 20.5 3.3e-83 280.0 20.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP55590.1 - 1.9e-21 76.4 36.8 6.6e-16 58.2 25.1 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2085 PF09858.9 OAP55590.1 - 0.98 9.9 13.8 7.2 7.2 0.7 3.8 2 1 2 4 4 4 0 Predicted membrane protein (DUF2085) Fungal_trans PF04082.18 OAP55591.1 - 9.8e-29 100.2 0.4 1.5e-28 99.5 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain AMP-binding PF00501.28 OAP55592.1 - 2.6e-76 256.9 0.0 1.8e-75 254.1 0.0 1.9 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAP55592.1 - 2.1e-16 60.7 0.1 5.7e-16 59.3 0.1 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Fungal_trans PF04082.18 OAP55593.1 - 7e-06 25.3 0.2 1.1e-05 24.6 0.2 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Epimerase PF01370.21 OAP55594.1 - 1.5e-05 24.6 0.0 2e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 OAP55594.1 - 0.024 13.8 0.0 1 8.5 0.0 2.3 2 0 0 2 2 2 0 Male sterility protein NAD_binding_10 PF13460.6 OAP55594.1 - 0.041 13.8 0.0 0.062 13.2 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding SGL PF08450.12 OAP55595.1 - 1.7e-10 40.9 0.5 7.2e-08 32.3 0.1 2.3 2 0 0 2 2 2 2 SMP-30/Gluconolactonase/LRE-like region Dynamin_M PF01031.20 OAP55597.1 - 0.00052 19.3 0.1 0.0007 18.9 0.1 1.2 1 0 0 1 1 1 1 Dynamin central region Med9 PF07544.13 OAP55597.1 - 0.067 13.3 0.9 1.5 8.9 0.0 2.9 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Med11 PF10280.9 OAP55597.1 - 0.073 13.5 0.0 3.2 8.2 0.0 2.6 2 1 1 3 3 3 0 Mediator complex protein DUF4795 PF16043.5 OAP55597.1 - 0.081 12.5 1.1 0.14 11.7 0.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) Alpha-E PF04168.12 OAP55597.1 - 0.092 12.5 0.1 0.85 9.3 0.0 2.3 2 1 1 3 3 3 0 A predicted alpha-helical domain with a conserved ER motif. DUF4800 PF16057.5 OAP55597.1 - 0.13 11.6 0.4 0.68 9.2 0.4 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4800) DDE_3 PF13358.6 OAP55598.1 - 5.3e-13 49.0 1.3 1.4e-12 47.6 0.4 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease Slx4 PF09494.10 OAP55598.1 - 0.13 12.2 0.0 0.86 9.6 0.0 2.1 2 0 0 2 2 2 0 Slx4 endonuclease ANTH PF07651.16 OAP55602.1 - 5.7e-77 258.4 0.0 5.7e-77 258.4 0.0 3.5 3 0 0 3 3 3 1 ANTH domain I_LWEQ PF01608.17 OAP55602.1 - 1.7e-54 184.2 7.2 1.7e-54 184.2 7.2 6.5 4 1 1 6 6 6 2 I/LWEQ domain ENTH PF01417.20 OAP55602.1 - 0.013 15.5 0.5 0.12 12.4 0.0 2.9 2 1 0 2 2 2 0 ENTH domain TcdB_N PF12918.7 OAP55602.1 - 0.14 12.5 2.4 0.39 11.0 0.6 2.8 2 0 0 2 2 2 0 TcdB toxin N-terminal helical domain Vma12 PF11712.8 OAP55602.1 - 3.5 7.7 9.2 19 5.3 9.2 2.3 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase PRKG1_interact PF15898.5 OAP55606.1 - 0.015 16.1 0.0 0.02 15.8 0.0 1.2 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain JmjC PF02373.22 OAP55609.1 - 1.6e-17 64.0 0.1 2.3e-17 63.5 0.1 1.2 1 0 0 1 1 1 1 JmjC domain, hydroxylase Uma2 PF05685.12 OAP55614.1 - 0.021 14.3 0.0 0.033 13.7 0.0 1.3 1 0 0 1 1 1 0 Putative restriction endonuclease adh_short_C2 PF13561.6 OAP55615.1 - 3.7e-51 174.0 7.1 1.1e-25 90.6 1.8 2.4 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP55615.1 - 5.6e-46 156.5 6.3 3.6e-43 147.3 6.3 2.1 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAP55615.1 - 1.3e-10 41.5 1.4 2.8e-10 40.4 0.7 1.8 1 1 1 2 2 2 1 KR domain DUF853 PF05872.12 OAP55615.1 - 0.012 14.2 0.7 0.23 10.0 0.1 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF853) F-box-like PF12937.7 OAP55616.1 - 0.00015 21.6 0.2 0.00041 20.2 0.2 1.8 1 0 0 1 1 1 1 F-box-like Peptidase_S24 PF00717.23 OAP55618.1 - 6.2e-09 35.7 0.0 6.1e-08 32.5 0.0 2.4 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 OAP55618.1 - 0.0001 22.1 0.1 0.0057 16.5 0.0 2.7 1 1 1 2 2 2 1 Signal peptidase, peptidase S26 Acetyltransf_4 PF13420.7 OAP55619.1 - 2.9e-11 43.8 0.0 4.8e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OAP55619.1 - 7.4e-08 32.7 0.1 3e-07 30.8 0.1 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAP55619.1 - 9.2e-08 32.3 0.0 1.8e-07 31.4 0.0 1.5 1 1 1 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 OAP55619.1 - 0.00043 21.0 0.0 0.00056 20.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OAP55619.1 - 0.0054 16.7 0.0 0.03 14.2 0.0 2.2 1 1 2 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 OAP55619.1 - 0.019 15.1 0.0 0.069 13.2 0.0 1.9 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAP55619.1 - 0.064 13.2 0.0 0.52 10.3 0.0 2.2 1 1 1 2 2 2 0 FR47-like protein VIT PF08487.10 OAP55620.1 - 1.6e-32 112.0 0.8 2.7e-32 111.3 0.8 1.4 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.6 OAP55620.1 - 1.1e-27 96.9 0.0 2.9e-27 95.5 0.0 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain VIT_2 PF13757.6 OAP55620.1 - 1.6e-12 47.1 0.2 2.9e-12 46.3 0.2 1.4 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_2 PF13519.6 OAP55620.1 - 3.7e-11 43.6 0.1 2.2e-10 41.1 0.0 2.2 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.28 OAP55620.1 - 9.1e-10 39.1 0.0 1.6e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 OAP55620.1 - 0.063 12.7 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein CwfJ_C_1 PF04677.15 OAP55621.1 - 1.5e-15 57.1 0.0 2.3e-15 56.5 0.0 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 OAP55621.1 - 4e-08 34.0 0.2 7.6e-08 33.2 0.2 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 DRIM PF07539.12 OAP55622.1 - 7.7e-130 434.1 3.0 2.9e-129 432.2 0.0 3.4 4 0 0 4 4 4 1 Down-regulated in metastasis DNA_ligase_A_N PF04675.14 OAP55622.1 - 0.044 14.1 0.3 3.3 8.0 0.0 3.9 3 0 0 3 3 3 0 DNA ligase N terminus V-ATPase_H_C PF11698.8 OAP55622.1 - 0.1 12.7 0.0 5.1 7.2 0.0 3.8 4 0 0 4 4 4 0 V-ATPase subunit H adh_short_C2 PF13561.6 OAP55623.1 - 4e-55 186.9 3.7 5.1e-55 186.6 3.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP55623.1 - 1.5e-43 148.5 4.8 2e-43 148.2 4.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase 3HCDH_N PF02737.18 OAP55623.1 - 0.19 11.6 1.3 0.3 11.0 0.2 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF936 PF06075.12 OAP55626.1 - 0.081 11.8 0.3 0.19 10.6 0.3 1.6 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) DUF1640 PF07798.11 OAP55626.1 - 0.15 12.1 1.2 0.22 11.6 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) OmpH PF03938.14 OAP55626.1 - 0.49 10.7 3.2 0.82 10.0 3.2 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) PH_4 PF15404.6 OAP55629.1 - 9.9e-55 185.2 0.0 9.6e-54 182.0 0.0 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain Spo7_2_N PF15407.6 OAP55629.1 - 4.4e-22 77.5 0.5 4.4e-22 77.5 0.5 2.4 2 0 0 2 2 2 1 Sporulation protein family 7 PH PF00169.29 OAP55629.1 - 4.4e-08 33.6 0.1 0.64 10.6 0.0 5.4 4 1 0 4 4 4 2 PH domain PH_6 PF15406.6 OAP55629.1 - 0.029 14.7 0.0 4.4 7.6 0.0 2.8 2 0 0 2 2 2 0 Pleckstrin homology domain GLTP PF08718.11 OAP55630.1 - 4.9e-41 140.5 0.0 6.1e-41 140.2 0.0 1.1 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) Macro PF01661.21 OAP55631.1 - 2.5e-37 127.5 0.0 3.5e-37 127.0 0.0 1.2 1 0 0 1 1 1 1 Macro domain Iso_dh PF00180.20 OAP55632.1 - 1.7e-77 260.9 0.0 2e-77 260.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase PTS_EIIC_2 PF13303.6 OAP55632.1 - 0.18 10.8 0.0 0.26 10.3 0.0 1.1 1 0 0 1 1 1 0 Phosphotransferase system, EIIC Isochorismatase PF00857.20 OAP55633.1 - 8.6e-36 123.7 0.1 9.9e-36 123.5 0.1 1.0 1 0 0 1 1 1 1 Isochorismatase family Abhydrolase_5 PF12695.7 OAP55633.1 - 0.1 12.3 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family ApbA PF02558.16 OAP55634.1 - 2.1e-27 95.6 0.0 3.1e-27 95.1 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 OAP55634.1 - 9.5e-22 77.5 0.0 1.5e-21 76.9 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal Fringe PF02434.16 OAP55636.1 - 1.7e-06 27.7 0.3 1.6e-05 24.5 0.3 2.2 1 1 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 OAP55636.1 - 7.7e-05 22.6 0.0 0.019 14.8 0.0 2.5 1 1 1 2 2 2 2 Galactosyltransferase Glyco_transf_34 PF05637.12 OAP55636.1 - 0.00038 20.3 0.6 0.00067 19.5 0.6 1.3 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family PAN_1 PF00024.26 OAP55636.1 - 0.0016 18.3 0.1 0.0033 17.4 0.1 1.4 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.6 OAP55636.1 - 0.0088 15.9 0.3 0.021 14.7 0.3 1.6 1 0 0 1 1 1 1 PAN domain PAN_3 PF08277.12 OAP55636.1 - 0.05 13.4 0.9 0.11 12.4 0.9 1.5 1 0 0 1 1 1 0 PAN-like domain HSBP1 PF06825.12 OAP55637.1 - 0.00046 20.0 2.9 0.22 11.4 1.5 2.6 1 1 1 2 2 2 2 Heat shock factor binding protein 1 DUF3294 PF07957.11 OAP55637.1 - 0.005 16.6 0.3 0.014 15.2 0.2 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3294) His_Phos_2 PF00328.22 OAP55637.1 - 0.0065 15.9 0.1 0.033 13.5 0.0 1.8 1 1 0 2 2 2 1 Histidine phosphatase superfamily (branch 2) Baculo_PEP_C PF04513.12 OAP55637.1 - 0.0083 16.2 0.0 0.012 15.7 0.0 1.3 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus FAM184 PF15665.5 OAP55637.1 - 0.011 15.5 0.1 0.016 15.0 0.1 1.3 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B Exonuc_VII_L PF02601.15 OAP55637.1 - 0.022 14.4 0.1 0.023 14.2 0.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Vps5 PF09325.10 OAP55637.1 - 0.043 13.4 0.0 0.16 11.5 0.2 1.7 2 0 0 2 2 2 0 Vps5 C terminal like EzrA PF06160.12 OAP55637.1 - 0.075 11.2 0.1 0.095 10.9 0.1 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA V_ATPase_I PF01496.19 OAP55637.1 - 0.1 10.5 0.1 0.11 10.5 0.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MbeD_MobD PF04899.12 OAP55637.1 - 0.13 12.4 0.2 0.51 10.5 0.2 2.1 1 1 0 1 1 1 0 MbeD/MobD like Tht1 PF04163.12 OAP55637.1 - 0.14 10.9 0.4 0.18 10.5 0.4 1.1 1 0 0 1 1 1 0 Tht1-like nuclear fusion protein DUF1664 PF07889.12 OAP55637.1 - 0.17 12.0 0.1 0.25 11.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Hemagglutinin PF00509.18 OAP55637.1 - 0.21 9.9 0.3 0.27 9.6 0.3 1.1 1 0 0 1 1 1 0 Haemagglutinin Sulfate_transp PF00916.20 OAP55638.1 - 1.2e-79 267.9 10.8 1.6e-79 267.4 10.8 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 OAP55638.1 - 2.4e-18 65.9 0.0 3.8e-18 65.2 0.0 1.3 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 OAP55638.1 - 0.017 15.4 0.0 0.14 12.5 0.0 2.4 2 1 0 2 2 2 0 STAS domain DUF4956 PF16316.5 OAP55638.1 - 0.2 11.3 3.6 5.7 6.6 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4956) MFS_MOT1 PF16983.5 OAP55638.1 - 3.7 8.0 15.6 0.033 14.6 4.2 2.8 3 0 0 3 3 3 0 Molybdate transporter of MFS superfamily IncD PF17628.2 OAP55638.1 - 4.9 6.9 6.0 0.86 9.4 0.2 2.4 3 0 0 3 3 3 0 Inclusion membrane protein D Asp PF00026.23 OAP55639.1 - 7.1e-08 32.2 0.0 0.00077 19.0 0.0 3.8 3 1 0 3 3 3 2 Eukaryotic aspartyl protease WW_like PF17890.1 OAP55639.1 - 0.11 12.5 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 Peptidoglycan hydrolase LytB WW-like domain DSBA PF01323.20 OAP55640.1 - 2.2e-13 50.4 0.1 2.7e-13 50.1 0.1 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_2 PF13098.6 OAP55640.1 - 0.15 12.5 0.2 4.8 7.7 0.0 2.2 2 1 0 2 2 2 0 Thioredoxin-like domain EIF_2_alpha PF07541.12 OAP55643.1 - 8.8e-38 129.0 0.0 1.6e-37 128.1 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 OAP55643.1 - 2.2e-13 50.4 0.6 4e-13 49.5 0.6 1.5 1 0 0 1 1 1 1 S1 RNA binding domain Baculo_PEP_C PF04513.12 OAP55645.1 - 0.00093 19.2 3.9 0.076 13.1 0.6 2.2 1 1 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus FPP PF05911.11 OAP55645.1 - 0.0012 17.2 4.3 0.0014 17.0 4.3 1.0 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil DUF1515 PF07439.11 OAP55645.1 - 0.0029 17.6 0.5 0.0055 16.7 0.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1515) TMPIT PF07851.13 OAP55645.1 - 0.0031 16.8 0.6 0.0043 16.3 0.6 1.2 1 0 0 1 1 1 1 TMPIT-like protein FAM76 PF16046.5 OAP55645.1 - 0.004 16.6 2.6 0.0049 16.3 2.6 1.1 1 0 0 1 1 1 1 FAM76 protein HMMR_N PF15905.5 OAP55645.1 - 0.0076 15.8 2.1 0.0099 15.4 2.1 1.3 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal Apolipoprotein PF01442.18 OAP55645.1 - 0.012 15.5 0.9 0.017 15.0 0.9 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain APG6_N PF17675.1 OAP55645.1 - 0.013 16.1 2.3 0.019 15.5 2.3 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region FapA PF03961.13 OAP55645.1 - 0.016 13.8 1.9 0.02 13.5 1.9 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A IFT57 PF10498.9 OAP55645.1 - 0.017 14.1 2.6 0.021 13.8 2.6 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 HAUS-augmin3 PF14932.6 OAP55645.1 - 0.017 14.7 1.2 0.022 14.3 1.2 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 HIP1_clath_bdg PF16515.5 OAP55645.1 - 0.019 15.6 7.1 0.76 10.4 6.5 2.2 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF1664 PF07889.12 OAP55645.1 - 0.027 14.5 2.2 0.073 13.1 1.7 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) RasGAP_C PF03836.15 OAP55645.1 - 0.028 14.6 3.3 0.13 12.4 3.3 1.9 1 1 0 1 1 1 0 RasGAP C-terminus Fez1 PF06818.15 OAP55645.1 - 0.029 14.8 1.3 0.037 14.5 1.3 1.2 1 0 0 1 1 1 0 Fez1 MscS_porin PF12795.7 OAP55645.1 - 0.036 13.6 2.9 0.11 12.0 2.9 1.6 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain FUSC PF04632.12 OAP55645.1 - 0.038 12.5 0.0 0.046 12.3 0.0 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family V_ATPase_I PF01496.19 OAP55645.1 - 0.046 11.7 2.8 0.057 11.3 2.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMF_TATA_bd PF12325.8 OAP55645.1 - 0.056 13.7 5.7 0.057 13.7 2.6 2.0 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding CENP-F_leu_zip PF10473.9 OAP55645.1 - 0.06 13.4 6.5 0.54 10.3 4.7 2.1 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATG16 PF08614.11 OAP55645.1 - 0.082 13.1 3.4 0.13 12.5 3.4 1.4 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) bZIP_1 PF00170.21 OAP55645.1 - 0.084 13.0 1.4 0.084 13.0 1.4 3.0 2 1 0 3 3 3 0 bZIP transcription factor COG2 PF06148.11 OAP55645.1 - 0.091 12.8 1.5 4 7.5 0.0 2.2 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Bacillus_HBL PF05791.11 OAP55645.1 - 0.1 12.4 3.2 0.26 11.1 3.2 1.7 1 1 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) CdvA PF18822.1 OAP55645.1 - 0.11 12.3 3.8 1.5 8.7 0.8 2.2 1 1 1 2 2 2 0 CdvA-like coiled-coil domain FlxA PF14282.6 OAP55645.1 - 0.13 12.3 3.6 0.12 12.4 1.7 1.8 1 1 1 2 2 2 0 FlxA-like protein Vps51 PF08700.11 OAP55645.1 - 0.18 11.9 4.5 0.22 11.6 2.3 2.1 1 1 1 2 2 2 0 Vps51/Vps67 Seryl_tRNA_N PF02403.22 OAP55645.1 - 0.21 11.8 2.0 0.64 10.3 1.6 1.9 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain YabA PF06156.13 OAP55645.1 - 0.22 12.2 3.5 0.43 11.2 3.3 1.6 1 1 0 1 1 1 0 Initiation control protein YabA DUF1640 PF07798.11 OAP55645.1 - 0.25 11.4 7.0 0.35 10.9 5.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) Muted PF14942.6 OAP55645.1 - 0.27 11.6 3.9 0.44 10.9 3.4 1.5 1 1 0 1 1 1 0 Organelle biogenesis, Muted-like protein Ax_dynein_light PF10211.9 OAP55645.1 - 0.28 11.1 2.9 0.54 10.2 2.5 1.6 1 1 1 2 2 2 0 Axonemal dynein light chain CLZ PF16526.5 OAP55645.1 - 0.31 11.4 5.3 5.8 7.4 0.1 2.6 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels BLOC1_2 PF10046.9 OAP55645.1 - 0.31 11.4 5.1 1.1 9.6 4.9 1.9 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TPR_MLP1_2 PF07926.12 OAP55645.1 - 0.31 11.1 3.4 0.92 9.6 2.2 1.9 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein FlaC_arch PF05377.11 OAP55645.1 - 0.33 11.4 6.8 0.14 12.6 2.0 2.5 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Tropomyosin_1 PF12718.7 OAP55645.1 - 0.39 10.8 4.2 0.93 9.6 3.9 1.7 1 1 1 2 2 2 0 Tropomyosin like Uso1_p115_C PF04871.13 OAP55645.1 - 0.39 11.1 5.6 0.76 10.2 3.6 1.9 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region CENP-H PF05837.12 OAP55645.1 - 0.54 10.7 3.7 0.84 10.1 2.3 1.8 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Fib_alpha PF08702.10 OAP55645.1 - 0.6 10.3 4.6 1.3 9.2 2.2 1.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family SseC PF04888.12 OAP55645.1 - 1.7 8.1 7.8 0.24 11.0 4.0 1.4 1 1 1 2 2 2 0 Secretion system effector C (SseC) like family Spc24 PF08286.11 OAP55645.1 - 2.5 8.4 6.3 8.5 6.7 3.6 2.2 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DASH_Dam1 PF08653.10 OAP55645.1 - 2.8 7.8 8.2 0.83 9.5 3.7 2.3 3 0 0 3 3 2 0 DASH complex subunit Dam1 Ion_trans PF00520.31 OAP55646.1 - 1.6e-07 30.8 20.5 8.6e-07 28.4 20.5 1.9 1 1 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 OAP55646.1 - 0.0013 17.5 19.5 0.033 12.9 19.2 2.6 2 1 0 2 2 2 1 Polycystin cation channel Ac76 PF05814.11 OAP55646.1 - 3.3 7.8 7.7 1.5 8.9 0.6 2.8 2 0 0 2 2 2 0 Orf76 (Ac76) DUF3488 PF11992.8 OAP55646.1 - 7.8 5.3 8.3 1.5 7.7 2.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3488) APH PF01636.23 OAP55647.1 - 1e-08 35.4 1.5 0.0016 18.4 0.1 2.6 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pkinase PF00069.25 OAP55647.1 - 6.2e-07 29.0 0.0 1.8e-06 27.5 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 OAP55647.1 - 3.8e-06 26.4 0.0 0.0012 18.3 0.0 2.9 2 1 1 3 3 3 2 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OAP55647.1 - 0.12 12.0 0.1 0.29 10.7 0.0 1.6 2 0 0 2 2 2 0 RIO1 family Aldo_ket_red PF00248.21 OAP55648.1 - 8.6e-10 38.3 0.0 1.3e-09 37.7 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family COR PF16095.5 OAP55648.1 - 0.04 13.7 0.0 0.79 9.5 0.0 2.1 2 0 0 2 2 2 0 C-terminal of Roc, COR, domain Sigma70_ner PF04546.13 OAP55648.1 - 0.29 11.0 5.2 0.43 10.4 5.2 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF5523 PF17661.1 OAP55648.1 - 0.39 10.4 6.2 1.7 8.3 4.5 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5523) SDA1 PF05285.12 OAP55648.1 - 3.8 6.8 9.8 5.4 6.3 9.8 1.1 1 0 0 1 1 1 0 SDA1 RRN3 PF05327.11 OAP55648.1 - 8.1 4.9 6.9 11 4.4 6.9 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Maf1 PF09174.10 OAP55649.1 - 4.4e-60 202.8 0.0 9.8e-60 201.7 0.0 1.6 1 0 0 1 1 1 1 Maf1 regulator Clat_adaptor_s PF01217.20 OAP55649.1 - 2.2e-52 176.8 1.9 3.3e-52 176.2 1.9 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain HOOK PF05622.12 OAP55650.1 - 6.4e-06 24.6 14.7 6.4e-06 24.6 14.7 2.7 1 1 1 2 2 2 1 HOOK protein Filament PF00038.21 OAP55650.1 - 8.9e-05 22.2 14.4 8.9e-05 22.2 14.4 4.2 2 1 2 4 4 4 1 Intermediate filament protein HAP1_N PF04849.13 OAP55650.1 - 0.00027 20.3 2.4 0.00027 20.3 2.4 3.9 2 1 1 3 3 2 1 HAP1 N-terminal conserved region TPR_MLP1_2 PF07926.12 OAP55650.1 - 0.00087 19.4 15.2 0.00087 19.4 15.2 5.4 4 1 1 5 5 5 1 TPR/MLP1/MLP2-like protein ADIP PF11559.8 OAP55650.1 - 0.00096 19.3 1.6 0.00096 19.3 1.6 4.8 3 1 2 5 5 5 1 Afadin- and alpha -actinin-Binding DUF3225 PF11533.8 OAP55650.1 - 0.0076 16.0 2.7 0.64 9.7 0.3 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF3225) Atg14 PF10186.9 OAP55650.1 - 0.068 12.2 34.8 2.2 7.3 7.0 3.1 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Surfac_D-trimer PF09006.11 OAP55650.1 - 0.074 13.0 0.3 0.3 11.0 0.1 2.2 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation Herpes_UL6 PF01763.16 OAP55650.1 - 2.4 6.6 15.2 1.2 7.6 2.7 2.4 2 0 0 2 2 2 0 Herpesvirus UL6 like Lectin_N PF03954.14 OAP55650.1 - 2.9 7.6 12.1 2.6 7.8 0.1 3.8 1 1 2 3 3 3 0 Hepatic lectin, N-terminal domain Bacillus_HBL PF05791.11 OAP55650.1 - 3.1 7.6 11.2 0.58 10.0 0.2 3.5 1 1 2 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) Pkinase PF00069.25 OAP55653.1 - 5.8e-22 78.3 0.0 7.2e-22 78.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP55653.1 - 3.6e-10 39.6 0.0 4.9e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAP55653.1 - 0.00048 19.0 0.0 0.00062 18.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OAP55653.1 - 0.013 14.9 0.0 0.02 14.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ABC1 PF03109.16 OAP55653.1 - 0.036 14.2 0.0 0.084 13.0 0.0 1.5 1 0 0 1 1 1 0 ABC1 family APH PF01636.23 OAP55653.1 - 0.08 12.9 0.0 0.34 10.8 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.25 OAP55654.1 - 2e-08 33.9 0.0 5e-08 32.6 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP55654.1 - 1e-07 31.6 0.1 9.2e-07 28.4 0.1 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase E1-E2_ATPase PF00122.20 OAP55655.1 - 5.7e-16 58.5 0.0 1.4e-15 57.3 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 OAP55655.1 - 1.4e-15 58.2 0.2 2.3e-08 34.6 0.5 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 OAP55655.1 - 1.3e-05 25.2 0.0 0.002 18.2 0.0 2.7 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 OAP55655.1 - 0.00041 20.2 0.1 0.012 15.3 0.0 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 OAP55655.1 - 0.067 12.7 0.3 0.39 10.2 0.0 2.2 3 0 0 3 3 3 0 Sucrose-6F-phosphate phosphohydrolase tRNA-synt_1c PF00749.21 OAP55656.1 - 8.1e-106 353.5 0.0 1.7e-105 352.4 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 OAP55656.1 - 6.6e-34 117.3 0.3 3e-31 108.6 0.0 3.8 4 0 0 4 4 4 1 tRNA synthetases class I (E and Q), anti-codon binding domain zf-AN1 PF01428.16 OAP55657.1 - 1.3e-05 25.3 3.5 1.3e-05 25.3 3.5 1.5 2 0 0 2 2 2 1 AN1-like Zinc finger FYVE PF01363.21 OAP55657.1 - 7.8e-05 22.7 4.1 0.00046 20.3 1.8 2.2 2 0 0 2 2 2 1 FYVE zinc finger zf-C2H2_4 PF13894.6 OAP55657.1 - 0.0014 19.3 2.7 0.35 11.8 0.0 2.8 2 0 0 2 2 2 1 C2H2-type zinc finger zf-Di19 PF05605.12 OAP55657.1 - 0.015 15.6 0.1 0.015 15.6 0.1 2.3 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding Dishevelled PF02377.15 OAP55657.1 - 0.025 15.1 0.0 0.059 13.8 0.0 1.6 1 1 0 1 1 1 0 Dishevelled specific domain IBR PF01485.21 OAP55657.1 - 0.035 14.3 2.4 0.057 13.7 1.3 1.8 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain zf-C2HC5 PF06221.13 OAP55657.1 - 0.039 13.9 1.4 0.32 11.0 0.4 2.3 2 0 0 2 2 2 0 Putative zinc finger motif, C2HC5-type Transp_Tc5_C PF04236.15 OAP55657.1 - 0.095 13.1 1.1 0.18 12.2 1.1 1.4 1 0 0 1 1 1 0 Tc5 transposase C-terminal domain zf-C2H2_2 PF12756.7 OAP55657.1 - 0.1 12.9 1.5 0.11 12.9 0.1 1.7 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C3HC PF07967.13 OAP55657.1 - 0.43 10.6 3.0 0.52 10.3 0.2 2.0 2 0 0 2 2 2 0 C3HC zinc finger-like Rbsn PF11464.8 OAP55658.1 - 3e-18 65.3 0.9 7.5e-18 64.0 0.9 1.7 1 0 0 1 1 1 1 Rabenosyn Rab binding domain FYVE PF01363.21 OAP55658.1 - 2.5e-16 59.6 4.7 4.2e-16 58.8 4.7 1.4 1 0 0 1 1 1 1 FYVE zinc finger YqaH PF17448.2 OAP55658.1 - 0.027 14.8 0.2 0.058 13.7 0.2 1.6 1 0 0 1 1 1 0 Uncharacterized YqaH-like LHH PF14411.6 OAP55658.1 - 0.074 13.2 0.1 0.18 12.0 0.1 1.7 1 0 0 1 1 1 0 A nuclease of the HNH/ENDO VII superfamily with conserved LHH TMF_TATA_bd PF12325.8 OAP55658.1 - 0.08 13.2 1.3 0.24 11.6 0.9 1.9 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding zf-Di19 PF05605.12 OAP55658.1 - 0.11 12.8 3.3 0.27 11.6 3.3 1.6 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Zn_Tnp_IS1595 PF12760.7 OAP55658.1 - 0.2 11.7 8.0 0.057 13.4 4.4 1.9 2 0 0 2 2 2 0 Transposase zinc-ribbon domain bZIP_1 PF00170.21 OAP55658.1 - 0.51 10.5 5.7 2.4 8.3 0.0 3.2 4 0 0 4 4 4 0 bZIP transcription factor FlgN PF05130.12 OAP55658.1 - 0.66 10.5 4.0 8.7 6.9 0.1 2.6 3 0 0 3 3 3 0 FlgN protein zf-B_box PF00643.24 OAP55658.1 - 2.3 8.4 7.3 2.2 8.5 2.7 2.3 2 0 0 2 2 2 0 B-box zinc finger zf-C2H2_4 PF13894.6 OAP55658.1 - 4.4 8.4 11.6 1.5 9.9 6.1 2.9 2 1 1 3 3 3 0 C2H2-type zinc finger zinc-ribbons_6 PF07191.12 OAP55658.1 - 4.4 7.3 8.1 9.9 6.2 5.0 2.2 2 0 0 2 2 2 0 zinc-ribbons ABC_tran_CTD PF16326.5 OAP55658.1 - 7.4 6.9 7.7 57 4.1 0.0 3.4 3 1 1 4 4 4 0 ABC transporter C-terminal domain CENP-L PF13092.6 OAP55659.1 - 4e-07 30.4 0.0 6.3e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Kinetochore complex Sim4 subunit Fta1 ADH_N PF08240.12 OAP55661.1 - 0.00059 19.7 0.0 0.00082 19.2 0.0 1.2 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain CH PF00307.31 OAP55664.1 - 3.9e-07 30.2 0.0 0.00061 20.0 0.0 2.5 2 0 0 2 2 2 2 Calponin homology (CH) domain IQ PF00612.27 OAP55664.1 - 0.46 10.4 5.9 0.21 11.5 3.1 2.0 2 0 0 2 2 2 0 IQ calmodulin-binding motif ERO1 PF04137.15 OAP55665.1 - 6.3e-133 443.3 0.1 7.6e-133 443.1 0.1 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Fungal_trans_2 PF11951.8 OAP55666.1 - 3.1e-09 36.1 1.6 2.7e-05 23.2 0.1 2.4 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP55666.1 - 0.0032 17.5 0.6 0.0065 16.6 0.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PSI_integrin PF17205.3 OAP55666.1 - 0.0061 16.3 0.3 0.018 14.7 0.3 1.9 1 0 0 1 1 1 1 Integrin plexin domain Vps62 PF06101.11 OAP55667.1 - 9.3e-13 47.3 6.4 8.3e-12 44.2 0.9 2.5 2 1 0 2 2 2 2 Vacuolar protein sorting-associated protein 62 MSA-2c PF12238.8 OAP55668.1 - 0.046 13.7 0.4 0.046 13.7 0.4 1.5 2 0 0 2 2 2 0 Merozoite surface antigen 2c Pkinase PF00069.25 OAP55669.1 - 3e-37 128.4 0.0 4.7e-37 127.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP55669.1 - 1.6e-19 70.2 0.0 2.2e-19 69.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 OAP55669.1 - 3.3e-07 30.5 0.0 8.2e-07 29.3 0.0 1.7 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 OAP55669.1 - 0.019 15.2 0.0 0.058 13.7 0.0 1.8 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain Pkinase_fungal PF17667.1 OAP55669.1 - 0.029 13.2 0.0 0.05 12.4 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 OAP55669.1 - 0.17 11.8 0.0 0.35 10.8 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pyr_redox_2 PF07992.14 OAP55670.1 - 3.9e-45 154.4 0.5 5.7e-45 153.8 0.5 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NIR_SIR PF01077.22 OAP55670.1 - 7.7e-21 74.2 0.0 1.4e-20 73.4 0.0 1.4 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Pyr_redox PF00070.27 OAP55670.1 - 4.6e-15 55.9 5.9 9.2e-14 51.8 0.4 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Fer2_BFD PF04324.15 OAP55670.1 - 6.7e-15 55.2 4.4 1.8e-11 44.2 4.1 2.7 2 0 0 2 2 2 2 BFD-like [2Fe-2S] binding domain Rieske PF00355.26 OAP55670.1 - 1.7e-11 43.9 0.3 1.1e-10 41.3 0.0 2.5 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain NIR_SIR_ferr PF03460.17 OAP55670.1 - 1e-09 38.1 0.0 3.1e-09 36.5 0.0 1.9 2 0 0 2 2 2 1 Nitrite/Sulfite reductase ferredoxin-like half domain Rieske_2 PF13806.6 OAP55670.1 - 3.4e-08 33.4 0.0 1.7e-07 31.1 0.0 2.2 2 0 0 2 2 2 1 Rieske-like [2Fe-2S] domain NAD_binding_9 PF13454.6 OAP55670.1 - 0.00036 20.5 0.1 2.3 8.2 0.0 3.3 2 1 1 3 3 3 2 FAD-NAD(P)-binding Rubredoxin_C PF18267.1 OAP55670.1 - 0.00052 19.9 0.0 3.8 7.5 0.0 3.6 3 0 0 3 3 3 2 Rubredoxin NAD+ reductase C-terminal domain AlaDh_PNT_C PF01262.21 OAP55670.1 - 0.026 13.8 0.4 4.2 6.6 0.1 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 OAP55670.1 - 0.057 13.9 0.3 1.3 9.5 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.19 OAP55670.1 - 0.073 12.4 0.3 0.35 10.2 0.0 2.2 2 1 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 OAP55670.1 - 0.26 11.6 0.5 23 5.3 0.1 2.7 2 0 0 2 2 2 0 TrkA-N domain Mo-co_dimer PF03404.16 OAP55671.1 - 8.8e-61 203.9 0.1 1.5e-60 203.2 0.1 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Oxidored_molyb PF00174.19 OAP55671.1 - 4e-56 189.3 0.0 9.7e-56 188.1 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain FAD_binding_6 PF00970.24 OAP55671.1 - 4.8e-35 119.9 0.0 8e-35 119.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 OAP55671.1 - 1.5e-30 106.0 0.0 3.4e-30 104.9 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.28 OAP55671.1 - 9.6e-20 70.5 0.0 2.5e-19 69.2 0.0 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 OAP55671.1 - 0.00078 19.6 0.0 0.075 13.2 0.0 2.4 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Ribosomal_S8e PF01201.22 OAP55672.1 - 6.9e-46 155.8 0.4 1.3e-45 155.0 0.4 1.4 1 1 0 1 1 1 1 Ribosomal protein S8e PA26 PF04636.13 OAP55672.1 - 0.073 12.0 0.6 0.096 11.6 0.6 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF1533 PF07550.11 OAP55673.1 - 0.029 14.2 0.0 0.053 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1533) Lactamase_B_5 PF14597.6 OAP55673.1 - 0.076 12.5 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily DSHCT PF08148.12 OAP55674.1 - 9.5e-52 175.0 0.3 2.1e-51 173.8 0.3 1.6 1 0 0 1 1 1 1 DSHCT (NUC185) domain Ski2_N PF17911.1 OAP55674.1 - 4.9e-35 120.3 0.0 1.5e-34 118.7 0.0 1.8 2 0 0 2 2 2 1 Ski2 N-terminal region rRNA_proc-arch PF13234.6 OAP55674.1 - 5.1e-21 75.8 0.2 8e-21 75.2 0.2 1.3 1 0 0 1 1 1 1 rRNA-processing arch domain DEAD PF00270.29 OAP55674.1 - 7.8e-19 68.1 0.0 1.6e-18 67.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAP55674.1 - 2.1e-06 28.0 0.0 7.5e-06 26.3 0.0 2.1 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAP55674.1 - 3.2e-05 24.0 0.0 6.3e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 OAP55674.1 - 0.11 12.8 0.3 1.1 9.6 0.0 2.6 3 0 0 3 3 3 0 AAA domain WD40 PF00400.32 OAP55675.1 - 9.5e-09 35.8 5.8 0.0001 23.0 1.2 3.9 3 0 0 3 3 3 2 WD domain, G-beta repeat PH PF00169.29 OAP55676.1 - 1.9e-06 28.3 0.3 4.8e-06 27.0 0.3 1.6 1 0 0 1 1 1 1 PH domain Tom5 PF10642.9 OAP55676.1 - 0.25 11.4 1.4 0.45 10.6 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial import receptor subunit or translocase Peptidase_S15 PF02129.18 OAP55676.1 - 0.8 9.2 7.4 0.61 9.6 5.6 1.7 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) tRNA-synt_2 PF00152.20 OAP55678.1 - 2.3e-74 250.3 0.0 3.1e-74 249.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.9 OAP55678.1 - 4.2e-20 71.9 1.0 1.1e-19 70.6 0.1 1.9 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2156) tRNA_anti-codon PF01336.25 OAP55678.1 - 1e-06 28.6 0.2 2.2e-06 27.5 0.2 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain SH3BGR PF04908.15 OAP55679.1 - 0.0014 18.7 0.0 0.02 15.0 0.0 2.7 2 0 0 2 2 2 1 SH3-binding, glutamic acid-rich protein GMC_oxred_N PF00732.19 OAP55680.1 - 8.8e-49 166.5 0.0 1.2e-48 166.1 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAP55680.1 - 3.7e-36 124.8 0.0 5.8e-36 124.2 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 OAP55680.1 - 2.2e-05 23.8 0.0 0.18 10.9 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 OAP55680.1 - 3.9e-05 23.8 0.1 0.00027 21.1 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 OAP55680.1 - 7.8e-05 21.9 0.0 0.00013 21.2 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 OAP55680.1 - 0.0006 19.5 0.1 0.009 15.6 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 OAP55680.1 - 0.013 14.7 0.0 0.8 8.9 0.0 2.5 3 0 0 3 3 3 0 Thi4 family Pyr_redox_2 PF07992.14 OAP55680.1 - 0.014 14.6 0.0 0.03 13.6 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAP55680.1 - 0.024 15.2 0.1 1.3 9.6 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 OAP55680.1 - 0.036 12.9 0.0 0.053 12.4 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Aldedh PF00171.22 OAP55681.1 - 3.4e-157 523.7 0.0 4.1e-157 523.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Glucosamine_iso PF01182.20 OAP55682.1 - 1.4e-22 80.7 0.0 2.2e-22 80.0 0.0 1.3 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Glyco_hydro_3 PF00933.21 OAP55683.1 - 3.9e-71 240.0 0.0 6.3e-71 239.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Acetyltransf_1 PF00583.25 OAP55683.1 - 2.9e-06 27.5 0.0 9.7e-06 25.8 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_6 PF13480.7 OAP55683.1 - 0.0041 17.3 0.1 0.048 13.8 0.0 2.7 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain Glyco_hydro_3_C PF01915.22 OAP55683.1 - 0.015 15.3 0.0 0.028 14.4 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain Acetyltransf_10 PF13673.7 OAP55683.1 - 0.056 13.4 0.1 0.19 11.7 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OAP55683.1 - 0.056 13.9 0.0 0.17 12.3 0.0 1.9 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain NDT80_PhoG PF05224.12 OAP55684.1 - 6.3e-38 130.9 0.0 9.2e-38 130.3 0.0 1.2 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family TPR_10 PF13374.6 OAP55685.1 - 1.2e-32 110.8 3.6 2.1e-10 40.1 0.0 5.8 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 OAP55685.1 - 8.7e-30 102.8 6.1 6.1e-13 48.9 0.1 5.6 2 1 3 5 5 5 4 Tetratricopeptide repeat TPR_MalT PF17874.1 OAP55685.1 - 8.4e-09 35.2 2.3 2e-08 34.0 2.3 1.6 1 0 0 1 1 1 1 MalT-like TPR region NB-ARC PF00931.22 OAP55685.1 - 2.2e-07 30.3 0.0 4.4e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain NACHT PF05729.12 OAP55685.1 - 1.1e-06 28.7 0.0 5.3e-06 26.5 0.0 2.2 2 0 0 2 2 2 1 NACHT domain TPR_8 PF13181.6 OAP55685.1 - 2.8e-05 24.0 0.5 3.8 8.0 0.0 4.1 4 0 0 4 4 3 2 Tetratricopeptide repeat AAA_16 PF13191.6 OAP55685.1 - 2.8e-05 24.5 0.5 0.00065 20.1 0.5 2.5 1 1 0 1 1 1 1 AAA ATPase domain TPR_17 PF13431.6 OAP55685.1 - 5.9e-05 23.2 0.1 7.2 7.2 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 OAP55685.1 - 0.00013 21.7 1.4 0.89 9.7 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_4 PF07721.14 OAP55685.1 - 0.0017 18.8 7.7 9.6 7.2 0.0 5.2 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 OAP55685.1 - 0.0072 16.1 0.4 13 5.8 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat AAA_22 PF13401.6 OAP55685.1 - 0.024 14.9 0.0 0.14 12.4 0.0 2.3 3 0 0 3 3 1 0 AAA domain TPR_19 PF14559.6 OAP55685.1 - 0.032 14.8 1.6 4.4 7.9 0.2 3.4 3 0 0 3 3 2 0 Tetratricopeptide repeat AAA_5 PF07728.14 OAP55685.1 - 0.062 13.3 0.0 0.19 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Metallophos_3 PF14582.6 OAP55685.1 - 0.11 11.8 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily ATPase_2 PF01637.18 OAP55685.1 - 0.13 12.1 0.0 0.85 9.5 0.0 2.0 1 1 0 2 2 2 0 ATPase domain predominantly from Archaea DUF4722 PF15849.5 OAP55685.1 - 0.15 11.8 0.0 3.4 7.4 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4722) PNP_UDP_1 PF01048.20 OAP55686.1 - 3.4e-08 33.0 0.3 2e-07 30.5 0.3 2.2 1 1 0 1 1 1 1 Phosphorylase superfamily CHASE3 PF05227.13 OAP55689.1 - 0.45 10.4 2.1 0.51 10.2 0.1 2.1 2 0 0 2 2 2 0 CHASE3 domain DUF2375 PF09558.10 OAP55690.1 - 0.1 12.6 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2375) Ribul_P_3_epim PF00834.19 OAP55691.1 - 8.9e-62 208.0 0.0 1.2e-60 204.4 0.0 2.0 1 1 0 1 1 1 1 Ribulose-phosphate 3 epimerase family ThiG PF05690.14 OAP55691.1 - 0.018 14.4 0.1 0.027 13.8 0.1 1.2 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG QRPTase_C PF01729.19 OAP55691.1 - 0.043 13.6 0.0 0.072 12.9 0.0 1.4 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain OMPdecase PF00215.24 OAP55691.1 - 0.044 13.4 0.0 0.06 12.9 0.0 1.3 1 0 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family EHN PF06441.12 OAP55692.1 - 4.4e-36 123.5 3.0 2.2e-35 121.3 0.1 2.4 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 OAP55692.1 - 8.9e-11 41.9 0.0 1.6e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Acyltransferase PF01553.21 OAP55695.1 - 1.2e-27 96.1 0.0 2.3e-27 95.2 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 OAP55695.1 - 9.4e-12 44.9 0.0 2e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase C-terminus DENN PF02141.21 OAP55697.1 - 1.4e-52 178.4 0.1 2.5e-52 177.6 0.1 1.5 1 0 0 1 1 1 1 DENN (AEX-3) domain dDENN PF03455.19 OAP55697.1 - 3.5e-10 39.7 0.1 7.7e-10 38.6 0.1 1.6 1 0 0 1 1 1 1 dDENN domain uDENN PF03456.18 OAP55697.1 - 6e-09 36.5 0.0 1.9e-08 34.9 0.0 2.0 1 0 0 1 1 1 1 uDENN domain C1_2 PF03107.16 OAP55697.1 - 9.6e-07 29.0 1.3 1.9e-06 28.0 1.3 1.5 1 0 0 1 1 1 1 C1 domain C1_1 PF00130.22 OAP55697.1 - 7.9e-05 22.5 1.0 0.00014 21.7 1.0 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) TetR_C_28 PF17937.1 OAP55697.1 - 0.034 14.6 1.6 0.13 12.7 1.6 2.0 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain DUF1730 PF08331.10 OAP55697.1 - 0.077 12.9 0.0 0.22 11.4 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1730) Zn_ribbon_17 PF17120.5 OAP55697.1 - 0.13 11.9 0.7 0.27 10.9 0.7 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Zf_RING PF16744.5 OAP55697.1 - 0.14 12.3 0.9 0.33 11.1 0.9 1.5 1 0 0 1 1 1 0 KIAA1045 RING finger Rnk_N PF14760.6 OAP55697.1 - 0.44 11.1 2.8 1.2 9.7 2.3 2.1 1 1 0 1 1 1 0 Rnk N-terminus CCDC-167 PF15188.6 OAP55697.1 - 6.1 7.3 6.3 2.1 8.8 1.9 2.4 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 DUF974 PF06159.13 OAP55698.1 - 2.8e-78 263.1 0.0 3.4e-78 262.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF974) DUF3237 PF11578.8 OAP55699.1 - 0.15 11.9 0.0 0.16 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3237) MFS_1 PF07690.16 OAP55700.1 - 1.9e-43 148.8 35.1 1.9e-43 148.8 35.1 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAP55700.1 - 1.8e-13 50.2 21.0 8.8e-13 47.9 10.8 2.6 2 1 0 2 2 2 2 Sugar (and other) transporter DASH_Dad2 PF08654.10 OAP55703.1 - 2.3e-29 101.7 0.0 3.3e-29 101.2 0.0 1.2 1 0 0 1 1 1 1 DASH complex subunit Dad2 IFT20 PF14931.6 OAP55703.1 - 0.066 13.4 2.8 0.45 10.7 2.9 2.1 1 1 1 2 2 2 0 Intraflagellar transport complex B, subunit 20 Shugoshin_N PF07558.11 OAP55704.1 - 3.7e-18 65.1 7.1 8.2e-18 64.0 7.1 1.6 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region Shugoshin_C PF07557.11 OAP55704.1 - 5.3e-09 35.7 4.3 5.3e-09 35.7 4.3 2.8 3 0 0 3 3 3 1 Shugoshin C terminus GIT_CC PF16559.5 OAP55704.1 - 0.035 14.0 0.7 0.082 12.8 0.7 1.6 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor DivIVA PF05103.13 OAP55704.1 - 0.19 11.8 2.3 0.48 10.5 2.3 1.8 1 0 0 1 1 1 0 DivIVA protein ZapB PF06005.12 OAP55704.1 - 5.6 7.5 8.0 46 4.6 8.0 2.6 1 1 0 1 1 1 0 Cell division protein ZapB Med21 PF11221.8 OAP55705.1 - 1.7e-37 128.9 6.2 1.1e-35 122.9 6.2 2.0 1 1 0 1 1 1 1 Subunit 21 of Mediator complex Pkinase PF00069.25 OAP55706.1 - 2.9e-12 46.5 0.0 6.4e-12 45.4 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP55706.1 - 6.9e-11 41.9 0.0 2.6e-10 40.0 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OAP55706.1 - 0.038 13.3 0.1 0.061 12.7 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ank_4 PF13637.6 OAP55707.1 - 9.4e-132 427.9 0.0 1.8e-10 41.1 0.0 11.3 1 1 13 14 14 14 14 Ankyrin repeats (many copies) Ank_2 PF12796.7 OAP55707.1 - 1.7e-107 352.2 0.0 9.1e-19 67.8 0.0 7.8 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OAP55707.1 - 2.8e-94 297.6 0.0 0.00021 21.4 0.0 15.1 15 0 0 15 15 14 14 Ankyrin repeat Ank PF00023.30 OAP55707.1 - 8.1e-93 301.2 0.0 7.2e-05 23.1 0.0 15.4 15 0 0 15 15 15 14 Ankyrin repeat Ank_5 PF13857.6 OAP55707.1 - 1e-80 264.7 0.0 1.3e-07 31.8 0.0 11.6 1 1 13 14 14 14 14 Ankyrin repeats (many copies) NACHT PF05729.12 OAP55707.1 - 2.2e-08 34.2 0.1 5.2e-08 33.0 0.1 1.7 2 0 0 2 2 1 1 NACHT domain DUF3734 PF12536.8 OAP55707.1 - 3.7e-07 30.4 0.0 5.7 7.3 0.0 5.8 2 1 3 5 5 5 1 Patatin phospholipase AAA_16 PF13191.6 OAP55707.1 - 1.2e-05 25.8 0.0 3.5e-05 24.3 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain DUF5431 PF17496.2 OAP55707.1 - 2.5e-05 24.3 0.0 23 5.2 0.0 8.4 12 0 0 12 12 10 0 Family of unknown function (DUF5431) KAP_NTPase PF07693.14 OAP55707.1 - 0.00066 19.0 0.0 0.0022 17.3 0.0 1.6 1 1 1 2 2 2 1 KAP family P-loop domain AAA_22 PF13401.6 OAP55707.1 - 0.0012 19.1 0.0 0.0072 16.6 0.0 2.3 3 0 0 3 3 3 1 AAA domain Abhydrolase_6 PF12697.7 OAP55707.1 - 0.0024 18.5 0.1 0.0064 17.1 0.1 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF829 PF05705.14 OAP55707.1 - 0.017 15.0 0.0 0.031 14.2 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF829) AAA PF00004.29 OAP55707.1 - 0.079 13.4 0.1 1 9.8 0.0 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Ploopntkinase3 PF18751.1 OAP55707.1 - 0.15 12.0 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 Cthe_2159 PF14262.6 OAP55707.1 - 0.18 11.1 0.0 19 4.5 0.0 3.6 1 1 2 4 4 4 0 Carbohydrate-binding domain-containing protein Cthe_2159 Thioesterase PF00975.20 OAP55707.1 - 0.18 11.9 0.0 0.32 11.1 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain HECT PF00632.25 OAP55709.1 - 8.1e-84 281.7 0.0 1.2e-83 281.2 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.27 OAP55709.1 - 0.054 13.3 0.3 0.18 11.7 0.3 2.0 1 0 0 1 1 1 0 IQ calmodulin-binding motif FSAP_sig_propep PF03032.15 OAP55709.1 - 0.63 10.1 2.9 1.6 8.8 2.9 1.6 1 0 0 1 1 1 0 Frog skin active peptide family signal and propeptide Pkinase_fungal PF17667.1 OAP55710.1 - 7.5e-134 446.5 0.0 9.6e-134 446.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 OAP55710.1 - 3.1e-05 23.5 0.0 5.9e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 OAP55710.1 - 0.0068 16.4 0.0 0.035 14.0 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Melibiase_2 PF16499.5 OAP55710.1 - 0.059 12.5 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 Alpha galactosidase A MauJ PF17419.2 OAP55710.1 - 0.11 11.9 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Methylamine utilization protein MauJ Pkinase PF00069.25 OAP55711.1 - 1.5e-13 50.7 0.0 3.3e-13 49.6 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP55711.1 - 1.2e-11 44.4 0.0 7.2e-11 41.9 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAP55711.1 - 0.0043 16.4 0.0 0.0055 16.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Thymosin PF01290.20 OAP55711.1 - 0.032 13.9 0.0 0.06 13.1 0.0 1.3 1 0 0 1 1 1 0 Thymosin beta-4 family Tetraspanin PF00335.20 OAP55712.1 - 1.2 8.8 12.1 0.12 12.1 5.2 2.1 1 1 0 2 2 2 0 Tetraspanin family DUF1218 PF06749.12 OAP55712.1 - 4.7 7.8 13.2 7.4 7.2 9.5 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1218) Abhydrolase_3 PF07859.13 OAP55714.1 - 4.9e-26 91.9 0.0 6.3e-26 91.5 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 OAP55714.1 - 4.9e-21 75.0 0.0 5.7e-21 74.8 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 OAP55714.1 - 0.16 11.4 0.0 0.4 10.1 0.0 1.6 2 0 0 2 2 2 0 Prolyl oligopeptidase family SPX PF03105.19 OAP55715.1 - 8.9e-42 144.4 3.3 5.6e-29 102.2 1.0 2.2 1 1 1 2 2 2 2 SPX domain Na_sulph_symp PF00939.19 OAP55715.1 - 2.2e-29 102.8 43.8 3.2e-29 102.3 43.8 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 OAP55715.1 - 1.4e-23 83.6 52.5 1.1e-17 64.2 21.2 2.8 2 1 1 3 3 3 2 Citrate transporter RTA1 PF04479.13 OAP55716.1 - 3.2e-61 206.5 11.5 4.8e-61 206.0 11.5 1.2 1 0 0 1 1 1 1 RTA1 like protein Oxidored_q2 PF00420.24 OAP55716.1 - 0.002 17.7 1.9 0.002 17.7 1.9 2.7 2 2 2 4 4 4 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L DUF588 PF04535.12 OAP55716.1 - 0.0026 17.6 12.2 0.004 16.9 3.6 2.4 1 1 0 2 2 2 2 Domain of unknown function (DUF588) Fungal_trans_2 PF11951.8 OAP55717.1 - 1.2e-05 24.3 1.3 0.0066 15.3 0.3 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP55717.1 - 0.00021 21.3 4.0 0.00062 19.8 4.0 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldo_ket_red PF00248.21 OAP55719.1 - 4.3e-46 157.4 0.0 7.1e-44 150.2 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Peripla_BP_4 PF13407.6 OAP55719.1 - 0.13 11.8 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 Periplasmic binding protein domain Glu-tRNAGln PF02686.15 OAP55720.1 - 2.3e-09 37.4 0.9 5.3e-09 36.2 0.9 1.6 1 0 0 1 1 1 1 Glu-tRNAGln amidotransferase C subunit SNAP PF14938.6 OAP55721.1 - 9.1e-113 376.4 19.9 1e-112 376.2 19.9 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 OAP55721.1 - 3.7e-06 27.1 15.6 0.0071 16.6 2.3 4.0 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 OAP55721.1 - 0.00058 19.7 8.3 2.7 8.2 0.1 5.3 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 OAP55721.1 - 0.031 14.5 11.4 1.3 9.4 0.4 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 OAP55721.1 - 0.37 11.0 18.5 9.5 6.6 0.7 5.7 4 2 3 7 7 7 0 Tetratricopeptide repeat TPR_6 PF13174.6 OAP55721.1 - 0.49 11.2 16.8 15 6.5 0.4 5.4 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 OAP55721.1 - 3.8 7.5 9.9 15 5.6 0.4 4.5 4 1 0 4 4 4 0 Tetratricopeptide repeat PI3_PI4_kinase PF00454.27 OAP55722.1 - 5.7e-42 144.2 0.0 8.4e-42 143.7 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase GATA PF00320.27 OAP55723.1 - 2e-15 56.1 2.6 4.3e-15 55.0 2.6 1.6 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.12 OAP55723.1 - 0.019 14.5 0.3 0.036 13.6 0.3 1.4 1 0 0 1 1 1 0 TFIIB zinc-binding FAM76 PF16046.5 OAP55723.1 - 0.077 12.3 9.4 0.82 9.0 5.6 2.2 1 1 0 2 2 2 0 FAM76 protein SUIM_assoc PF16619.5 OAP55723.1 - 2.7 8.1 10.6 6.8 6.8 4.2 2.7 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 AMP-binding PF00501.28 OAP55725.1 - 1.3e-72 244.8 0.0 1.6e-72 244.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAP55725.1 - 7.4e-18 65.3 0.3 1.4e-17 64.4 0.3 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain RNA_pol_Rpc4 PF05132.14 OAP55726.1 - 5.6 7.4 7.5 9.6 6.6 7.5 1.5 1 0 0 1 1 1 0 RNA polymerase III RPC4 Na_Ca_ex PF01699.24 OAP55727.1 - 5.5e-24 84.9 19.6 5.6e-15 55.6 11.9 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Rgp1 PF08737.10 OAP55728.1 - 1.9e-124 416.0 0.0 3.7e-124 415.1 0.0 1.5 1 0 0 1 1 1 1 Rgp1 Arrestin_N PF00339.29 OAP55728.1 - 0.0021 18.1 0.0 0.0047 17.0 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Diphthamide_syn PF01866.17 OAP55729.1 - 3.9e-116 387.8 0.0 4.9e-116 387.4 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Rhomboid PF01694.22 OAP55730.1 - 6.7e-06 26.2 1.4 1.3e-05 25.2 1.4 1.4 1 0 0 1 1 1 1 Rhomboid family DUF1751 PF08551.10 OAP55730.1 - 0.00035 21.1 2.9 0.00065 20.2 2.9 1.4 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) RNA_pol_Rpc4 PF05132.14 OAP55730.1 - 0.00074 20.0 3.0 0.00074 20.0 3.0 1.6 2 0 0 2 2 2 1 RNA polymerase III RPC4 DDHD PF02862.17 OAP55730.1 - 0.069 13.3 3.2 0.11 12.7 3.2 1.4 1 0 0 1 1 1 0 DDHD domain PIP5K PF01504.18 OAP55730.1 - 0.36 10.0 1.2 0.42 9.8 1.2 1.2 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase Pox_Ag35 PF03286.14 OAP55730.1 - 1.7 8.4 25.1 2.9 7.6 25.1 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein SID-1_RNA_chan PF13965.6 OAP55730.1 - 1.7 7.0 4.1 2.2 6.6 4.0 1.3 1 1 0 1 1 1 0 dsRNA-gated channel SID-1 Mpp10 PF04006.12 OAP55730.1 - 2.6 6.4 35.1 3.1 6.1 35.1 1.1 1 0 0 1 1 1 0 Mpp10 protein RPN2_C PF18004.1 OAP55730.1 - 3.3 7.6 25.6 5.4 6.9 25.6 1.4 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Nop14 PF04147.12 OAP55730.1 - 4.6 5.3 39.5 5.6 5.0 39.5 1.1 1 0 0 1 1 1 0 Nop14-like family RNA_polI_A34 PF08208.11 OAP55730.1 - 8.2 6.5 30.9 13 5.8 30.9 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DUF2722 PF10846.8 OAP55730.1 - 9.2 5.1 18.0 0.25 10.2 11.9 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) PH_TFIIH PF08567.11 OAP55731.1 - 1.4e-24 86.3 0.0 3e-24 85.2 0.0 1.6 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain BSD PF03909.17 OAP55731.1 - 5.7e-24 83.9 6.2 2e-13 50.1 0.5 2.8 3 0 0 3 3 3 2 BSD domain PTB PF08416.13 OAP55731.1 - 0.04 14.1 0.0 1.8 8.7 0.0 2.8 3 0 0 3 3 3 0 Phosphotyrosine-binding domain FTA2 PF13095.6 OAP55732.1 - 6.4e-06 26.0 0.0 0.00045 19.9 0.0 2.2 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 MFS_1 PF07690.16 OAP55733.1 - 2.4e-26 92.5 35.5 2.4e-26 92.5 35.5 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily adh_short_C2 PF13561.6 OAP55734.1 - 6.5e-58 196.1 3.4 8e-58 195.8 3.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP55734.1 - 1.4e-44 151.9 4.4 1.8e-44 151.5 4.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase 3HCDH_N PF02737.18 OAP55734.1 - 0.026 14.4 0.8 0.054 13.4 0.8 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Fungal_lectin PF07938.12 OAP55737.1 - 2.4e-46 158.5 7.3 1.7e-34 119.6 1.2 2.5 2 1 1 3 3 3 2 Fungal fucose-specific lectin HC2 PF07382.11 OAP55737.1 - 5.5e-06 26.6 21.0 8.6e-06 26.0 21.0 1.2 1 0 0 1 1 1 1 Histone H1-like nucleoprotein HC2 Atrophin-1 PF03154.15 OAP55737.1 - 2.3 6.4 6.6 2.9 6.0 0.3 2.1 1 1 1 2 2 2 0 Atrophin-1 family ERM PF00769.19 OAP55737.1 - 6.1 6.6 26.1 9.2 6.0 26.1 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family HNH_2 PF13391.6 OAP55738.1 - 8e-12 45.1 0.1 3.9e-11 42.9 0.0 2.2 2 0 0 2 2 2 1 HNH endonuclease adh_short_C2 PF13561.6 OAP55739.1 - 4.1e-56 190.2 2.3 5.1e-56 189.8 2.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP55739.1 - 1.9e-44 151.5 0.4 2.6e-44 151.0 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Methyltransf_25 PF13649.6 OAP55739.1 - 0.014 16.1 0.1 0.028 15.1 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 OAP55739.1 - 0.022 15.4 0.0 0.052 14.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Peptidase_M16_C PF05193.21 OAP55740.1 - 1.6e-19 70.6 0.0 5.8e-17 62.3 0.0 2.7 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 OAP55740.1 - 6.1e-06 26.3 0.1 1.9e-05 24.7 0.0 1.9 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) M16C_assoc PF08367.11 OAP55740.1 - 0.018 14.2 2.7 1.3 8.1 0.0 2.4 2 0 0 2 2 2 0 Peptidase M16C associated Ank_2 PF12796.7 OAP55741.1 - 1e-31 109.3 0.0 3.7e-11 43.5 0.0 4.4 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAP55741.1 - 3.9e-25 87.9 0.2 3.3e-07 30.7 0.0 5.4 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAP55741.1 - 8.1e-19 65.8 2.5 0.013 16.0 0.0 7.5 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.6 OAP55741.1 - 2e-18 66.2 1.2 2.6e-05 24.4 0.0 5.6 2 1 5 7 7 7 6 Ankyrin repeats (many copies) Ank PF00023.30 OAP55741.1 - 2.5e-14 53.0 6.2 0.002 18.5 0.0 6.6 5 1 0 5 5 5 3 Ankyrin repeat NACHT PF05729.12 OAP55741.1 - 1.3e-08 34.9 0.1 3e-08 33.8 0.1 1.6 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 OAP55741.1 - 0.0005 20.4 0.0 0.0014 18.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OAP55741.1 - 0.0025 18.2 0.0 0.0085 16.5 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain Pkinase PF00069.25 OAP55742.1 - 2.4e-26 92.7 0.0 4.9e-26 91.7 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP55742.1 - 4.6e-14 52.3 0.0 9.4e-14 51.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase FOXP-CC PF16159.5 OAP55742.1 - 0.068 13.8 0.6 0.27 11.9 0.6 2.1 1 0 0 1 1 1 0 FOXP coiled-coil domain GGA_N-GAT PF18308.1 OAP55742.1 - 0.18 11.4 0.4 18 5.0 0.1 2.7 2 0 0 2 2 2 0 GGA N-GAT domain HeLo PF14479.6 OAP55743.1 - 0.039 13.8 0.8 0.073 12.9 0.8 1.4 1 0 0 1 1 1 0 Prion-inhibition and propagation CDC37_C PF08564.10 OAP55743.1 - 0.11 12.7 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 Cdc37 C terminal domain Sod_Fe_C PF02777.18 OAP55744.1 - 2.2e-33 114.4 0.5 2.2e-33 114.4 0.5 1.5 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 OAP55744.1 - 5.7e-30 103.6 1.7 8.2e-30 103.1 1.1 1.6 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain DUF5617 PF18493.1 OAP55744.1 - 0.042 14.0 0.0 0.08 13.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5617) PUA_3 PF17785.1 OAP55745.1 - 0.12 12.2 0.0 0.37 10.6 0.1 1.8 2 0 0 2 2 2 0 PUA-like domain BLOC1S3 PF15753.5 OAP55746.1 - 9.5 6.3 7.8 1e+02 3.0 7.8 2.4 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 WD40 PF00400.32 OAP55747.1 - 1.6e-21 76.2 23.5 7.2e-07 29.8 0.4 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat NLE PF08154.12 OAP55747.1 - 1.8e-16 60.4 0.2 3e-16 59.7 0.2 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.8 OAP55747.1 - 0.021 13.5 8.6 7.4 5.1 0.2 3.9 2 2 0 3 3 3 0 Nucleoporin Nup120/160 Dsl1_C PF11989.8 OAP55748.1 - 4.9e-05 23.1 2.0 8.5e-05 22.4 0.0 2.4 3 0 0 3 3 3 1 Retrograde transport protein Dsl1 C terminal Fib_alpha PF08702.10 OAP55748.1 - 1 9.5 14.7 0.76 10.0 6.5 3.8 3 1 1 4 4 4 0 Fibrinogen alpha/beta chain family AA_permease PF00324.21 OAP55749.1 - 6.4e-144 480.1 32.5 8e-144 479.8 32.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAP55749.1 - 9.4e-38 130.1 33.4 1.1e-37 129.9 33.4 1.0 1 0 0 1 1 1 1 Amino acid permease DUF4781 PF16013.5 OAP55749.1 - 0.00075 18.4 0.4 0.0014 17.5 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4781) Methyltransf_16 PF10294.9 OAP55751.1 - 1.7e-45 154.9 0.0 2.7e-45 154.2 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 OAP55751.1 - 0.00078 19.3 0.0 0.0012 18.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAP55751.1 - 0.0022 18.6 0.1 0.0052 17.5 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 OAP55751.1 - 0.003 17.3 0.0 0.0046 16.7 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 OAP55751.1 - 0.052 13.1 0.1 0.082 12.4 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase small domain ApbA PF02558.16 OAP55751.1 - 0.18 11.5 0.0 7.6 6.2 0.0 2.6 2 1 1 3 3 3 0 Ketopantoate reductase PanE/ApbA Orn_Arg_deC_N PF02784.16 OAP55752.1 - 1e-80 270.7 0.0 1.5e-80 270.2 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 OAP55752.1 - 4.3e-21 75.0 0.0 5.5e-21 74.6 0.0 1.4 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.24 OAP55752.1 - 2.4e-05 23.9 0.0 4.4e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel DUF3425 PF11905.8 OAP55753.1 - 2e-19 69.8 0.0 5.2e-19 68.4 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) FTO_CTD PF12934.7 OAP55753.1 - 0.076 12.8 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 FTO C-terminal domain adh_short PF00106.25 OAP55754.1 - 5.3e-21 75.0 0.0 6.6e-20 71.4 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP55754.1 - 9.6e-12 45.0 0.0 1.7e-11 44.1 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP55754.1 - 8.5e-09 35.6 0.0 1.2e-08 35.1 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAP55754.1 - 0.0012 18.3 0.0 0.0021 17.6 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family cobW PF02492.19 OAP55755.1 - 6.2e-41 139.9 0.0 1.1e-40 139.2 0.0 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.14 OAP55755.1 - 0.00034 20.5 0.1 0.0012 18.8 0.0 1.9 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B RsgA_GTPase PF03193.16 OAP55755.1 - 0.002 18.1 0.0 2.3 8.1 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 OAP55755.1 - 0.016 15.5 0.0 0.036 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 OAP55755.1 - 0.044 13.5 0.4 0.97 9.2 0.2 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain Viral_helicase1 PF01443.18 OAP55755.1 - 0.13 11.9 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase CobW_C PF07683.14 OAP55755.1 - 0.15 12.0 0.0 3.8 7.5 0.0 2.5 1 1 0 1 1 1 0 Cobalamin synthesis protein cobW C-terminal domain DSBA PF01323.20 OAP55756.1 - 2e-13 50.6 0.0 2.3e-13 50.4 0.0 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain WD40 PF00400.32 OAP55758.1 - 1.7e-65 215.3 33.5 1.9e-10 41.1 0.2 6.9 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAP55758.1 - 1.9e-19 69.8 1.0 0.067 13.5 0.0 6.5 1 1 5 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OAP55758.1 - 1.8e-14 53.5 0.9 0.24 10.3 0.0 6.2 1 1 5 6 6 6 6 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 OAP55758.1 - 8.8e-12 44.4 10.0 0.081 11.5 0.1 6.2 2 1 4 6 6 6 6 Nucleoporin Nup120/160 NACHT PF05729.12 OAP55758.1 - 2.1e-09 37.5 0.0 4.4e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 NACHT domain PD40 PF07676.12 OAP55758.1 - 8.2e-09 35.2 7.5 12 6.0 0.1 6.5 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat WD40_like PF17005.5 OAP55758.1 - 1.4e-07 31.2 0.0 4 6.7 0.0 5.4 1 1 5 6 6 6 3 WD40-like domain CX PF01705.19 OAP55758.1 - 4.5e-06 27.1 0.0 9.1 6.9 0.0 5.8 5 0 0 5 5 5 0 CX module AAA_16 PF13191.6 OAP55758.1 - 0.00013 22.4 1.7 0.00027 21.4 0.0 2.4 3 0 0 3 3 2 1 AAA ATPase domain APS_kinase PF01583.20 OAP55758.1 - 0.026 14.4 0.1 0.047 13.6 0.1 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA PF00004.29 OAP55758.1 - 0.026 14.9 0.0 1.1 9.7 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) SEO_C PF14577.6 OAP55758.1 - 0.029 13.8 0.1 0.054 12.9 0.1 1.3 1 0 0 1 1 1 0 Sieve element occlusion C-terminus HTH_20 PF12840.7 OAP55758.1 - 0.035 14.2 0.1 0.13 12.4 0.1 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain AAA_30 PF13604.6 OAP55758.1 - 0.069 12.9 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 OAP55758.1 - 0.081 13.2 0.1 3.1 8.1 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.6 OAP55758.1 - 0.11 13.1 0.0 0.37 11.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 OAP55758.1 - 0.17 11.8 0.0 1.6 8.7 0.0 2.6 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) PALB2_WD40 PF16756.5 OAP55758.1 - 0.34 9.8 10.7 1.1 8.2 0.5 4.0 1 1 5 6 6 6 0 Partner and localizer of BRCA2 WD40 domain Proteasome_A_N PF10584.9 OAP55758.1 - 0.67 9.7 15.7 1.1e+02 2.6 0.0 6.6 6 0 0 6 6 6 0 Proteasome subunit A N-terminal signature Phage_stabilise PF11134.8 OAP55758.1 - 6.2 5.6 6.7 43 2.8 0.1 3.8 1 1 4 5 5 5 0 Phage stabilisation protein CorA PF01544.18 OAP55761.1 - 0.01 15.2 0.7 0.033 13.5 0.0 2.0 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein CFEM PF05730.11 OAP55762.1 - 1.2e-13 50.9 11.5 2e-13 50.2 11.5 1.3 1 0 0 1 1 1 1 CFEM domain DUF2615 PF11027.8 OAP55762.1 - 0.02 15.0 0.5 0.02 15.0 0.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2615) Gamma-thionin PF00304.20 OAP55762.1 - 0.083 13.2 0.3 0.083 13.2 0.3 1.7 2 0 0 2 2 2 0 Gamma-thionin family YebO PF13974.6 OAP55762.1 - 1.6 8.9 5.8 0.94 9.6 0.9 2.6 2 0 0 2 2 2 0 YebO-like protein DUF2985 PF11204.8 OAP55763.1 - 1.9e-21 76.0 4.0 3.6e-21 75.1 4.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) MSA-2c PF12238.8 OAP55763.1 - 0.32 11.0 4.3 0.72 9.8 4.3 1.6 1 0 0 1 1 1 0 Merozoite surface antigen 2c MT0933_antitox PF14013.6 OAP55764.1 - 0.27 11.6 4.6 2.8 8.3 2.0 3.0 2 1 0 2 2 2 0 MT0933-like antitoxin protein HTH_Tnp_Tc5 PF03221.16 OAP55765.1 - 1.5e-10 41.0 0.0 2.3e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_50 PF18024.1 OAP55765.1 - 0.0028 17.2 0.1 0.01 15.4 0.1 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_psq PF05225.16 OAP55765.1 - 0.033 13.9 0.2 0.058 13.1 0.2 1.4 1 0 0 1 1 1 0 helix-turn-helix, Psq domain HTH_28 PF13518.6 OAP55765.1 - 0.078 13.1 0.2 1.6 8.9 0.1 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain R3H PF01424.22 OAP55766.1 - 3.8e-15 55.6 0.1 7.8e-15 54.6 0.1 1.6 1 0 0 1 1 1 1 R3H domain DUF1682 PF07946.14 OAP55766.1 - 5.9 6.0 9.1 10 5.2 9.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Proteasome PF00227.26 OAP55767.1 - 1.1e-28 100.1 0.0 1.3e-28 99.8 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit MMM1 PF10296.9 OAP55768.1 - 2.2e-05 23.7 0.0 5.7e-05 22.3 0.0 1.6 1 1 1 2 2 2 1 Maintenance of mitochondrial morphology protein 1 SCIMP PF15050.6 OAP55768.1 - 2.9 8.4 5.7 4.1 7.9 0.0 3.4 4 0 0 4 4 4 0 SCIMP protein Sugar_tr PF00083.24 OAP55769.1 - 2.3e-88 297.1 28.3 2.7e-88 296.8 28.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP55769.1 - 2e-15 56.6 48.9 2.6e-09 36.5 18.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily APH PF01636.23 OAP55770.1 - 1.3e-15 58.0 1.4 2.5e-15 57.1 1.4 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 OAP55770.1 - 0.00098 18.8 0.0 0.0025 17.4 0.0 1.6 1 1 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.25 OAP55770.1 - 0.062 12.7 0.0 6.5 6.0 0.0 2.1 2 0 0 2 2 2 0 Protein kinase domain RIO1 PF01163.22 OAP55770.1 - 0.16 11.5 0.0 2.3 7.8 0.0 2.0 2 0 0 2 2 2 0 RIO1 family adh_short_C2 PF13561.6 OAP55771.1 - 1.3e-44 152.5 1.3 1.6e-44 152.2 1.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP55771.1 - 3.1e-36 124.7 0.9 4.9e-36 124.0 0.9 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAP55771.1 - 8.7e-13 48.6 0.3 1.1e-12 48.2 0.3 1.2 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 OAP55771.1 - 2.8e-07 30.3 0.1 6.2e-07 29.1 0.1 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 OAP55771.1 - 1.1e-06 28.4 0.3 1.8e-06 27.6 0.3 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 OAP55771.1 - 0.042 13.7 0.2 0.072 13.0 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain YjeF_N PF03853.15 OAP55771.1 - 0.068 13.1 0.6 0.15 11.9 0.1 1.8 2 0 0 2 2 2 0 YjeF-related protein N-terminus ApbA PF02558.16 OAP55771.1 - 0.068 12.8 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 OAP55771.1 - 0.13 12.9 0.6 1.1 9.9 0.1 2.2 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent TAL_FSA PF00923.19 OAP55772.1 - 3.4e-28 98.8 0.0 4.4e-28 98.5 0.0 1.1 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase DNA_pol_B PF00136.21 OAP55773.1 - 6.2e-101 338.4 0.0 9.1e-101 337.8 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 OAP55773.1 - 7.2e-20 71.4 0.0 6.3e-13 48.6 0.0 2.4 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain Fungal_trans PF04082.18 OAP55773.1 - 2.5e-08 33.3 0.3 4.2e-08 32.6 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C4pol PF14260.6 OAP55773.1 - 6e-05 23.4 2.1 6e-05 23.4 2.1 2.1 2 0 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta Slu7 PF11708.8 OAP55774.1 - 5.8e-66 223.0 20.1 5.8e-66 223.0 20.1 2.9 2 1 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.6 OAP55774.1 - 0.0095 15.7 0.4 0.025 14.3 0.4 1.7 1 0 0 1 1 1 1 Zinc knuckle Uds1 PF15456.6 OAP55778.1 - 1.1e-41 142.0 5.7 1.1e-41 142.0 5.7 5.7 5 1 1 6 6 6 1 Up-regulated During Septation DUF4618 PF15397.6 OAP55778.1 - 0.00026 20.5 22.8 0.00026 20.5 22.8 5.6 4 1 1 6 6 6 2 Domain of unknown function (DUF4618) Golgin_A5 PF09787.9 OAP55778.1 - 0.0057 16.2 19.3 0.0057 16.2 19.3 5.5 2 2 3 6 6 6 1 Golgin subfamily A member 5 HR1 PF02185.16 OAP55778.1 - 0.02 15.0 0.9 0.02 15.0 0.9 8.8 5 3 2 7 7 7 0 Hr1 repeat NPV_P10 PF05531.12 OAP55778.1 - 4.1 7.9 32.8 2.2 8.8 0.4 7.0 5 2 0 6 6 6 0 Nucleopolyhedrovirus P10 protein DPM3 PF08285.11 OAP55778.1 - 8.3 6.7 8.0 0.65 10.2 0.2 3.2 3 0 0 3 3 3 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) MFS_1 PF07690.16 OAP55779.1 - 2.5e-30 105.6 30.7 4.4e-30 104.8 30.7 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 OAP55779.1 - 8.2e-08 31.2 14.5 2.2e-06 26.5 1.4 2.4 2 1 1 3 3 3 2 MFS/sugar transport protein Sugar_tr PF00083.24 OAP55779.1 - 1.7e-05 23.9 20.2 0.003 16.5 5.0 3.7 2 2 0 2 2 2 2 Sugar (and other) transporter UCR_hinge PF02320.16 OAP55780.1 - 4e-14 52.5 6.7 7.8e-14 51.6 6.7 1.5 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein Mpp10 PF04006.12 OAP55780.1 - 0.22 9.9 18.8 0.28 9.6 18.8 1.2 1 0 0 1 1 1 0 Mpp10 protein DUF4211 PF13926.6 OAP55780.1 - 0.4 10.7 3.9 0.66 10.0 3.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4211) Nop14 PF04147.12 OAP55780.1 - 1.1 7.3 22.8 1.2 7.2 22.8 1.0 1 0 0 1 1 1 0 Nop14-like family RR_TM4-6 PF06459.12 OAP55780.1 - 1.4 8.7 9.5 1.5 8.6 9.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SpoIIIAH PF12685.7 OAP55780.1 - 1.5 8.6 9.2 1.7 8.4 9.2 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein DUF913 PF06025.12 OAP55780.1 - 2.2 7.1 4.4 2.3 7.1 4.4 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) PAF PF15715.5 OAP55780.1 - 2.8 8.5 13.8 4.6 7.8 13.8 1.6 1 1 0 1 1 1 0 PCNA-associated factor histone like domain DNA_pol_phi PF04931.13 OAP55780.1 - 3.3 5.7 27.8 3.7 5.5 27.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi Zip PF02535.22 OAP55780.1 - 5.4 6.1 6.8 5.7 6.1 6.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter CDC45 PF02724.14 OAP55780.1 - 5.6 5.1 17.7 6.1 5.0 17.7 1.1 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 OAP55780.1 - 5.7 6.2 22.0 6.3 6.0 22.0 1.0 1 0 0 1 1 1 0 BUD22 Presenilin PF01080.17 OAP55780.1 - 9 4.9 7.1 9.4 4.9 7.1 1.1 1 0 0 1 1 1 0 Presenilin Vps36_ESCRT-II PF11605.8 OAP55781.1 - 0.0045 17.1 0.0 0.015 15.5 0.0 1.8 2 0 0 2 2 2 1 Vacuolar protein sorting protein 36 Vps36 Glyoxalase_6 PF18029.1 OAP55782.1 - 2.9e-06 28.0 0.0 5.7e-06 27.1 0.0 1.5 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.25 OAP55782.1 - 0.034 14.3 0.0 1 9.6 0.0 2.1 2 0 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily NAD_binding_1 PF00175.21 OAP55783.1 - 8.1e-15 55.4 0.0 1.9e-14 54.2 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Globin PF00042.22 OAP55783.1 - 8.4e-08 32.7 0.0 4.3e-07 30.5 0.0 2.1 2 0 0 2 2 2 1 Globin NAD_binding_6 PF08030.12 OAP55783.1 - 5.6e-06 26.6 0.0 1.5e-05 25.2 0.0 1.6 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_6 PF00970.24 OAP55783.1 - 5.1e-05 23.5 0.0 0.0001 22.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Protoglobin PF11563.8 OAP55783.1 - 0.00027 20.9 0.2 0.0005 20.0 0.2 1.4 1 0 0 1 1 1 1 Protoglobin MFS_1 PF07690.16 OAP55784.1 - 7.2e-25 87.6 20.7 7.2e-25 87.6 20.7 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAP55784.1 - 5.9e-09 35.3 3.4 5.9e-09 35.3 3.4 3.1 3 0 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 OAP55784.1 - 7.4e-06 24.7 1.6 7.4e-06 24.7 1.6 2.2 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) PUCC PF03209.15 OAP55784.1 - 0.0055 15.8 4.8 0.011 14.8 0.1 2.7 2 1 0 2 2 2 1 PUCC protein Sugar_tr PF00083.24 OAP55785.1 - 6.8e-14 51.6 2.9 8.5e-14 51.3 2.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter Arrestin_C PF02752.22 OAP55786.1 - 7.8e-12 45.8 0.0 1.9e-09 38.0 0.0 3.1 3 0 0 3 3 3 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 OAP55786.1 - 2e-06 27.9 0.0 5.8e-06 26.4 0.0 1.8 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain adh_short PF00106.25 OAP55791.1 - 1.2e-19 70.6 0.0 1.7e-19 70.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP55791.1 - 9.6e-19 67.9 0.0 1.2e-18 67.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP55791.1 - 2.1e-05 24.5 0.0 3.6e-05 23.8 0.0 1.4 1 1 0 1 1 1 1 KR domain DUF460 PF04312.13 OAP55791.1 - 0.014 15.1 0.0 0.022 14.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF460) TPR_10 PF13374.6 OAP55793.1 - 2.3e-57 189.4 29.2 8.6e-09 35.0 0.2 8.4 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_12 PF13424.6 OAP55793.1 - 4.2e-51 171.1 33.7 9.8e-13 48.2 2.1 5.5 2 1 4 7 7 7 6 Tetratricopeptide repeat Patatin PF01734.22 OAP55793.1 - 3.1e-22 79.8 0.1 9.1e-22 78.2 0.0 1.9 2 0 0 2 2 1 1 Patatin-like phospholipase TPR_14 PF13428.6 OAP55793.1 - 7.4e-19 66.8 14.5 0.0059 17.3 0.2 8.0 9 0 0 9 9 6 5 Tetratricopeptide repeat TPR_19 PF14559.6 OAP55793.1 - 2.5e-17 63.1 12.0 0.00019 21.9 0.2 6.1 1 1 5 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.6 OAP55793.1 - 2e-16 58.7 0.3 1.2 9.5 0.1 7.9 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_20 PF14561.6 OAP55793.1 - 7.2e-15 55.1 13.1 0.15 12.4 0.1 7.2 2 1 4 6 6 6 5 Tetratricopeptide repeat ANAPC3 PF12895.7 OAP55793.1 - 5e-14 52.3 1.4 0.55 10.5 0.1 6.1 1 1 4 5 5 5 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 OAP55793.1 - 1.1e-13 50.2 14.3 0.17 12.1 0.1 7.7 9 0 0 9 9 7 6 Tetratricopeptide repeat NB-ARC PF00931.22 OAP55793.1 - 7.7e-12 44.9 0.1 3e-11 43.0 0.0 1.9 2 0 0 2 2 2 1 NB-ARC domain TPR_6 PF13174.6 OAP55793.1 - 7.6e-10 38.8 9.0 4.9 8.0 0.2 8.0 8 0 0 8 8 7 1 Tetratricopeptide repeat PPR PF01535.20 OAP55793.1 - 2e-09 37.1 0.0 5 7.6 0.0 6.3 6 0 0 6 6 6 1 PPR repeat TPR_16 PF13432.6 OAP55793.1 - 1e-07 32.5 22.9 0.15 12.7 0.4 6.9 7 0 0 7 7 6 5 Tetratricopeptide repeat AAA_22 PF13401.6 OAP55793.1 - 4.4e-07 30.2 0.0 2e-06 28.1 0.0 2.1 2 0 0 2 2 1 1 AAA domain TPR_7 PF13176.6 OAP55793.1 - 4.5e-07 29.5 18.0 3.1 8.1 0.1 7.1 7 0 0 7 7 7 2 Tetratricopeptide repeat AAA_16 PF13191.6 OAP55793.1 - 1.2e-05 25.8 0.1 1.2e-05 25.8 0.1 3.1 3 1 0 3 3 3 1 AAA ATPase domain TPR_4 PF07721.14 OAP55793.1 - 0.0001 22.6 49.8 1.2 9.9 0.6 9.1 10 0 0 10 10 8 6 Tetratricopeptide repeat Fis1_TPR_N PF14852.6 OAP55793.1 - 0.00033 20.3 2.3 18 5.1 0.0 5.3 5 0 0 5 5 5 0 Fis1 N-terminal tetratricopeptide repeat TPR_1 PF00515.28 OAP55793.1 - 0.00083 19.1 11.1 20 5.2 0.1 7.3 8 0 0 8 8 8 0 Tetratricopeptide repeat SRP54 PF00448.22 OAP55793.1 - 0.0021 17.7 0.0 0.005 16.5 0.0 1.6 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain PPR_1 PF12854.7 OAP55793.1 - 0.0046 16.6 7.2 17 5.2 0.1 5.5 5 0 0 5 5 5 0 PPR repeat NACHT PF05729.12 OAP55793.1 - 0.013 15.4 0.0 0.031 14.2 0.0 1.7 1 0 0 1 1 1 0 NACHT domain SNAP PF14938.6 OAP55793.1 - 0.018 14.5 0.6 2 7.7 0.1 2.7 1 1 1 2 2 2 0 Soluble NSF attachment protein, SNAP AAA_18 PF13238.6 OAP55793.1 - 0.13 12.8 0.2 0.73 10.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain ThiD2 PF17792.1 OAP55793.1 - 0.17 12.4 26.7 20 5.6 0.2 6.7 2 1 2 5 5 5 0 ThiD2 family AAA_5 PF07728.14 OAP55793.1 - 0.18 11.8 2.6 0.63 10.0 0.0 3.3 6 0 0 6 6 3 0 AAA domain (dynein-related subfamily) TPR_11 PF13414.6 OAP55793.1 - 0.67 9.7 12.0 92 2.9 0.3 6.2 6 0 0 6 6 6 0 TPR repeat FAD_binding_3 PF01494.19 OAP55795.1 - 6.8e-18 65.0 3.1 1.3e-16 60.8 3.1 2.6 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 OAP55795.1 - 0.00087 19.5 0.4 0.002 18.3 0.4 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SE PF08491.10 OAP55795.1 - 0.0015 17.7 0.0 0.0024 17.0 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase DAO PF01266.24 OAP55795.1 - 0.018 14.6 2.7 0.029 14.0 2.8 1.6 1 1 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAP55795.1 - 0.044 13.0 0.0 0.066 12.4 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAP55795.1 - 0.059 12.6 0.1 0.1 11.8 0.1 1.3 1 0 0 1 1 1 0 Thi4 family DUF3665 PF12427.8 OAP55795.1 - 1.8 8.4 7.2 0.7 9.6 3.6 2.3 2 1 0 2 2 2 0 Branched-chain amino acid aminotransferase Glyco_hydro_28 PF00295.17 OAP55796.1 - 2.5e-46 158.2 11.9 9.5e-46 156.3 11.9 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 Amidase PF01425.21 OAP55797.1 - 1.6e-81 274.6 0.0 1.9e-81 274.4 0.0 1.1 1 0 0 1 1 1 1 Amidase Polysacc_deac_1 PF01522.21 OAP55798.1 - 8.1e-12 45.1 0.0 1.5e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase Fungal_trans PF04082.18 OAP55799.1 - 6e-26 91.1 0.3 9.2e-26 90.4 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP55799.1 - 1.1e-08 35.0 7.9 2.1e-08 34.1 7.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 OAP55799.1 - 0.0093 14.8 1.3 0.025 13.4 1.3 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain ABC_tran_CTD PF16326.5 OAP55799.1 - 0.029 14.6 2.7 17 5.7 0.1 3.5 2 1 1 3 3 3 0 ABC transporter C-terminal domain Dicer_N PF17895.1 OAP55799.1 - 0.09 12.6 0.1 1.8 8.4 0.0 2.8 3 0 0 3 3 3 0 Giardia Dicer N-terminal domain Transp_cyt_pur PF02133.15 OAP55800.1 - 3.3e-94 316.2 35.1 3.8e-94 316.0 35.1 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin MFS_1 PF07690.16 OAP55801.1 - 5.2e-44 150.6 41.3 2.6e-43 148.3 41.9 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 OAP55801.1 - 9.7e-19 67.2 8.0 1.8e-18 66.4 8.0 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 OAP55801.1 - 9.4e-16 57.7 3.8 9.4e-16 57.7 3.8 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter YlaH PF14036.6 OAP55801.1 - 0.064 13.6 0.5 0.28 11.6 0.1 2.3 2 0 0 2 2 2 0 YlaH-like protein AA_permease_2 PF13520.6 OAP55802.1 - 5.9e-52 176.9 50.7 7e-52 176.7 50.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAP55802.1 - 3e-24 85.5 44.9 4e-24 85.1 44.9 1.1 1 0 0 1 1 1 1 Amino acid permease Colicin_V PF02674.16 OAP55802.1 - 3.4 7.6 35.5 0.19 11.7 4.8 4.5 3 1 1 4 4 4 0 Colicin V production protein YtxH PF12732.7 OAP55804.1 - 0.018 15.6 0.0 0.087 13.4 0.0 2.0 1 1 0 1 1 1 0 YtxH-like protein KLRAQ PF10205.9 OAP55804.1 - 0.063 13.5 4.7 0.14 12.4 4.7 1.6 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein Csm1_N PF18504.1 OAP55804.1 - 0.12 12.7 7.2 0.048 14.0 3.0 2.5 2 1 1 3 3 3 0 Csm1 N-terminal domain PLAC9 PF15205.6 OAP55804.1 - 0.26 11.7 2.6 0.61 10.5 0.4 2.4 1 1 1 2 2 2 0 Placenta-specific protein 9 PKcGMP_CC PF16808.5 OAP55804.1 - 0.3 11.0 7.7 0.4 10.6 3.8 2.5 1 1 1 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase TMF_DNA_bd PF12329.8 OAP55804.1 - 4.1 7.5 9.1 2.5 8.2 6.1 2.2 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Acyltransferase PF01553.21 OAP55805.1 - 2.3e-09 37.0 0.0 0.0022 17.6 0.0 2.3 2 0 0 2 2 2 2 Acyltransferase DUF4010 PF13194.6 OAP55805.1 - 2.5 7.7 5.5 0.54 9.9 1.7 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4010) WD40 PF00400.32 OAP55806.1 - 7e-32 109.0 11.2 9.5e-06 26.3 0.0 7.9 8 0 0 8 8 8 5 WD domain, G-beta repeat F-box-like PF12937.7 OAP55806.1 - 6.5e-12 45.2 0.1 1.2e-11 44.3 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAP55806.1 - 2.3e-06 27.3 0.0 5.3e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 F-box domain ANAPC4_WD40 PF12894.7 OAP55806.1 - 9.5e-05 22.6 0.3 4 7.8 0.0 4.2 2 2 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OAP55806.1 - 0.00051 18.8 1.6 1.1 7.8 0.9 3.0 2 1 0 2 2 2 2 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 OAP55806.1 - 0.0017 17.4 0.0 0.48 9.3 0.0 2.5 2 0 0 2 2 2 2 Partner and localizer of BRCA2 WD40 domain MgtE_N PF03448.17 OAP55806.1 - 0.02 15.5 0.1 0.054 14.1 0.1 1.6 1 0 0 1 1 1 0 MgtE intracellular N domain Prenyltransf PF01255.19 OAP55807.1 - 1.5e-83 279.7 0.1 5.6e-83 277.9 0.1 1.7 1 1 0 1 1 1 1 Putative undecaprenyl diphosphate synthase OTT_1508_deam PF14441.6 OAP55808.1 - 3.6e-19 68.5 0.3 8.7e-19 67.3 0.3 1.7 1 0 0 1 1 1 1 OTT_1508-like deaminase Peptidase_M41 PF01434.18 OAP55809.1 - 6.5e-55 185.9 0.4 1.1e-54 185.2 0.4 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 OAP55809.1 - 4.9e-43 146.7 0.0 1.8e-42 144.9 0.0 2.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OAP55809.1 - 7.7e-10 38.4 0.1 2.3e-09 36.9 0.1 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 OAP55809.1 - 4.9e-06 26.6 0.0 1.8e-05 24.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 OAP55809.1 - 2.5e-05 24.6 0.0 0.015 15.6 0.0 3.5 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OAP55809.1 - 2.6e-05 24.6 0.1 0.00017 22.1 0.1 2.3 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 OAP55809.1 - 0.00015 21.5 0.0 0.00043 20.1 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 OAP55809.1 - 0.00042 19.6 0.0 0.001 18.4 0.0 1.6 2 0 0 2 2 2 1 TIP49 P-loop domain DUF815 PF05673.13 OAP55809.1 - 0.0019 17.4 0.0 0.0043 16.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 OAP55809.1 - 0.002 17.9 0.0 0.0045 16.7 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.6 OAP55809.1 - 0.0038 17.4 0.0 0.0098 16.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 OAP55809.1 - 0.0039 16.6 0.3 0.011 15.1 0.3 1.7 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI FumaraseC_C PF10415.9 OAP55809.1 - 0.015 15.7 1.1 0.038 14.4 1.1 1.7 1 0 0 1 1 1 0 Fumarase C C-terminus AAA_7 PF12775.7 OAP55809.1 - 0.017 14.7 0.7 0.36 10.3 0.0 2.9 4 0 0 4 4 4 0 P-loop containing dynein motor region AAA_18 PF13238.6 OAP55809.1 - 0.036 14.6 0.1 0.14 12.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 OAP55809.1 - 0.037 14.3 0.9 0.064 13.5 0.0 1.9 2 0 0 2 2 1 0 AAA domain NACHT PF05729.12 OAP55809.1 - 0.037 14.0 0.1 0.24 11.3 0.1 2.2 2 0 0 2 2 2 0 NACHT domain AAA_14 PF13173.6 OAP55809.1 - 0.049 13.7 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 OAP55809.1 - 0.069 12.7 0.3 0.76 9.3 0.2 2.3 1 1 0 2 2 2 0 AAA domain TniB PF05621.11 OAP55809.1 - 0.076 12.4 0.0 0.34 10.3 0.0 2.0 2 0 0 2 2 2 0 Bacterial TniB protein Zeta_toxin PF06414.12 OAP55809.1 - 0.078 12.2 2.0 0.36 10.1 0.7 2.3 1 1 1 2 2 2 0 Zeta toxin TsaE PF02367.17 OAP55809.1 - 0.12 12.3 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_11 PF13086.6 OAP55809.1 - 0.39 10.4 4.4 6.3 6.5 0.0 3.1 3 0 0 3 3 3 0 AAA domain FliG_N PF14842.6 OAP55809.1 - 1 9.9 3.3 2.3 8.8 3.3 1.6 1 0 0 1 1 1 0 FliG N-terminal domain DUF4448 PF14610.6 OAP55810.1 - 0.046 13.5 0.1 0.085 12.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DUF4381 PF14316.6 OAP55810.1 - 0.058 13.6 0.1 0.089 13.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF1223 PF06764.11 OAP55811.1 - 1.9e-50 171.7 0.0 2.7e-50 171.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1223) K_trans PF02705.16 OAP55813.1 - 1.2e-184 614.8 12.7 1.5e-184 614.5 12.7 1.1 1 0 0 1 1 1 1 K+ potassium transporter RA PF00788.23 OAP55814.1 - 1.3e-07 32.1 0.0 3.3e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain FEZ PF07763.13 OAP55814.1 - 0.00043 20.1 0.4 0.00078 19.3 0.4 1.4 1 0 0 1 1 1 1 FEZ-like protein Helo_like_N PF17111.5 OAP55814.1 - 0.017 14.5 1.3 0.028 13.8 1.3 1.3 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins SesA PF17107.5 OAP55814.1 - 0.13 12.5 1.5 0.2 11.9 0.2 1.9 2 1 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases TPR_10 PF13374.6 OAP55816.1 - 1.1e-111 362.1 19.5 2e-13 49.7 0.1 10.3 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_12 PF13424.6 OAP55816.1 - 5.1e-106 347.1 54.2 7.1e-19 67.9 3.2 8.5 1 1 8 9 9 9 9 Tetratricopeptide repeat TPR_7 PF13176.6 OAP55816.1 - 1.8e-37 124.6 21.4 0.0014 18.5 0.1 10.5 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_17 PF13431.6 OAP55816.1 - 6.2e-21 73.2 12.4 0.1 13.1 0.0 8.9 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_16 PF13432.6 OAP55816.1 - 2.2e-19 69.8 8.9 0.0012 19.4 0.5 8.2 6 2 1 7 7 7 4 Tetratricopeptide repeat TPR_1 PF00515.28 OAP55816.1 - 5e-19 67.3 18.3 0.021 14.6 0.1 9.4 10 0 0 10 10 9 5 Tetratricopeptide repeat TPR_8 PF13181.6 OAP55816.1 - 4.7e-17 60.7 24.3 0.0037 17.4 0.2 9.6 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_4 PF07721.14 OAP55816.1 - 5.8e-14 51.2 0.0 6.1 7.8 0.0 8.3 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_MalT PF17874.1 OAP55816.1 - 4.5e-12 46.0 9.4 0.00023 20.7 0.7 4.2 1 1 3 4 4 4 3 MalT-like TPR region TPR_2 PF07719.17 OAP55816.1 - 2.7e-10 39.5 18.3 0.71 10.1 0.0 9.4 9 0 0 9 9 9 2 Tetratricopeptide repeat NB-ARC PF00931.22 OAP55816.1 - 3.1e-10 39.7 0.1 6.5e-09 35.4 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain TPR_14 PF13428.6 OAP55816.1 - 2e-09 37.5 16.9 13 7.0 0.0 9.9 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_19 PF14559.6 OAP55816.1 - 4e-09 36.9 9.6 0.12 12.9 0.5 5.8 2 2 4 6 6 6 5 Tetratricopeptide repeat PPR PF01535.20 OAP55816.1 - 4.1e-09 36.1 5.7 16 6.1 0.0 8.1 8 0 0 8 8 7 0 PPR repeat MCPVI PF02993.14 OAP55816.1 - 2e-08 34.3 2.8 0.74 9.6 0.0 6.0 1 1 6 7 7 7 2 Minor capsid protein VI DUF4919 PF16266.5 OAP55816.1 - 3.9e-06 26.9 7.7 0.29 11.1 0.1 5.2 1 1 6 7 7 7 3 Domain of unknown function (DUF4919) DUF1319 PF07028.11 OAP55816.1 - 0.00025 21.2 2.1 3.6 7.8 0.0 4.4 1 1 5 6 6 6 2 Protein of unknown function (DUF1319) Abhydrolase_6 PF12697.7 OAP55816.1 - 0.0003 21.4 0.6 0.0012 19.5 0.2 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family AAA_16 PF13191.6 OAP55816.1 - 0.00062 20.2 0.4 0.011 16.2 0.4 3.0 1 1 0 1 1 1 1 AAA ATPase domain BTAD PF03704.17 OAP55816.1 - 0.00083 19.8 22.2 1.2 9.5 0.2 7.3 2 1 5 7 7 7 2 Bacterial transcriptional activator domain Hydrolase_4 PF12146.8 OAP55816.1 - 0.0014 17.9 0.0 0.013 14.8 0.0 2.7 3 0 0 3 3 2 1 Serine aminopeptidase, S33 GAGBD PF16828.5 OAP55816.1 - 0.0026 17.9 5.5 1.5 8.9 0.1 3.9 2 1 2 4 4 3 2 GAG-binding domain on surface antigen DUF676 PF05057.14 OAP55816.1 - 0.0035 16.9 0.0 0.0072 15.9 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF2277 PF10041.9 OAP55816.1 - 0.0037 17.6 0.4 13 6.2 0.0 4.5 3 1 1 4 4 2 0 Uncharacterized conserved protein (DUF2277) A2M PF00207.22 OAP55816.1 - 0.0039 17.0 0.0 27 4.7 0.0 4.9 1 1 2 5 5 5 0 Alpha-2-macroglobulin family Cutinase PF01083.22 OAP55816.1 - 0.01 15.8 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 0 Cutinase Death PF00531.22 OAP55816.1 - 0.013 15.7 1.6 1.3e+02 2.8 0.0 6.2 8 0 0 8 8 7 0 Death domain bZIP_C PF12498.8 OAP55816.1 - 0.058 14.4 0.4 57 4.7 0.0 4.8 3 1 1 4 4 3 0 Basic leucine-zipper C terminal FUR PF01475.19 OAP55816.1 - 0.23 11.6 6.6 65 3.7 0.0 5.5 7 0 0 7 7 6 0 Ferric uptake regulator family DUF4404 PF14357.6 OAP55816.1 - 0.62 10.7 11.1 25 5.6 0.1 4.8 2 1 4 6 6 6 0 Domain of unknown function (DUF4404) Na_H_Exchanger PF00999.21 OAP55818.1 - 7.4e-40 136.9 28.0 9.6e-40 136.5 28.0 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family TauD PF02668.16 OAP55819.1 - 7.6e-56 189.8 0.7 8.9e-56 189.6 0.7 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family adh_short PF00106.25 OAP55820.1 - 0.0008 18.9 0.0 0.24 10.8 0.0 3.3 2 1 0 2 2 2 2 short chain dehydrogenase FGGY_C PF02782.16 OAP55821.1 - 9.6e-71 237.6 0.3 1.4e-70 237.1 0.3 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 OAP55821.1 - 1.1e-65 221.7 0.0 1.4e-65 221.3 0.0 1.1 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain DUF3429 PF11911.8 OAP55822.1 - 2e-43 148.2 12.0 2.7e-43 147.7 12.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) COX6A PF02046.15 OAP55823.1 - 1.9e-53 179.7 0.2 2.2e-53 179.5 0.2 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa ANAPC5 PF12862.7 OAP55824.1 - 1.3e-34 118.1 3.8 1.3e-34 118.1 3.8 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 5 TPR_4 PF07721.14 OAP55824.1 - 0.0057 17.2 14.1 2.7 8.9 0.6 5.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 OAP55824.1 - 0.011 16.3 11.2 1.2 9.7 0.0 5.0 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 OAP55824.1 - 0.013 15.4 9.8 0.22 11.4 0.7 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_21 PF09976.9 OAP55824.1 - 0.06 13.0 6.0 5.1 6.7 0.0 4.0 4 1 1 5 5 5 0 Tetratricopeptide repeat-like domain HrpB1_HrpK PF09613.10 OAP55824.1 - 0.12 12.0 0.4 20 4.8 0.0 2.7 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_7 PF13176.6 OAP55824.1 - 0.35 11.0 4.0 98 3.3 0.2 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 OAP55824.1 - 0.41 11.0 17.2 3.2 8.1 2.4 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 OAP55824.1 - 1 9.6 5.9 16 5.9 0.3 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat SAICAR_synt PF01259.18 OAP55825.1 - 2.4e-103 345.2 0.1 2.8e-103 344.9 0.1 1.0 1 0 0 1 1 1 1 SAICAR synthetase CIA30 PF08547.12 OAP55826.1 - 5.9e-40 136.9 0.0 1.2e-39 135.9 0.0 1.5 1 1 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) RRM_1 PF00076.22 OAP55827.1 - 1.3e-26 92.2 0.2 7.3e-13 48.2 0.1 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 OAP55827.1 - 0.13 12.5 0.1 9.3 6.5 0.0 2.4 2 0 0 2 2 2 0 RRM-like domain Ank_2 PF12796.7 OAP55828.1 - 3.4e-60 200.6 0.0 2.1e-18 66.6 0.0 4.9 2 1 3 5 5 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 OAP55828.1 - 4.1e-50 166.1 0.0 5e-05 23.6 0.0 9.6 9 0 0 9 9 9 9 Ankyrin repeat Ank_3 PF13606.6 OAP55828.1 - 1.8e-47 153.8 0.0 0.00037 20.7 0.0 9.7 9 0 0 9 9 9 9 Ankyrin repeat Ank_4 PF13637.6 OAP55828.1 - 1e-40 137.6 0.0 6.2e-07 29.8 0.0 6.0 3 2 1 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 OAP55828.1 - 1.6e-37 127.1 0.0 7.5e-07 29.3 0.0 7.7 1 1 8 9 9 9 9 Ankyrin repeats (many copies) NACHT PF05729.12 OAP55828.1 - 7.7e-09 35.7 0.6 2.4e-07 30.8 0.0 2.4 2 0 0 2 2 2 1 NACHT domain SesA PF17107.5 OAP55828.1 - 6.6e-06 26.3 0.1 2.2e-05 24.6 0.1 1.9 2 0 0 2 2 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases AAA_22 PF13401.6 OAP55828.1 - 8.8e-06 26.0 0.2 3.4e-05 24.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain DUF4350 PF14258.6 OAP55828.1 - 0.00036 20.9 4.4 63 4.1 0.0 6.9 7 2 1 9 9 8 0 Domain of unknown function (DUF4350) Nse4-Nse3_bdg PF15412.6 OAP55828.1 - 0.00048 20.2 2.5 39 4.5 0.0 6.3 7 0 0 7 7 7 0 Binding domain of Nse4/EID3 to Nse3-MAGE HA1 PF18239.1 OAP55828.1 - 0.0033 17.3 0.1 4.7 7.1 0.0 4.0 1 1 4 5 5 5 1 Hemagglutinin I DHR10 PF18595.1 OAP55828.1 - 0.013 15.5 2.9 0.074 13.1 0.1 2.9 3 0 0 3 3 3 0 Designed helical repeat protein 10 domain DUF2383 PF09537.10 OAP55828.1 - 0.019 15.3 0.0 0.1 13.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF2383) Syntaxin_2 PF14523.6 OAP55828.1 - 0.13 12.6 2.5 0.98 9.8 0.0 3.2 4 0 0 4 4 4 0 Syntaxin-like protein ATPase PF06745.13 OAP55828.1 - 0.14 11.5 0.0 0.38 10.1 0.0 1.7 1 0 0 1 1 1 0 KaiC PEGA PF08308.11 OAP55828.1 - 0.3 11.0 0.9 18 5.3 0.1 4.0 4 1 1 5 5 5 0 PEGA domain Ank_4 PF13637.6 OAP55829.1 - 8e-10 39.1 1.3 1.5e-06 28.7 0.1 3.3 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 OAP55829.1 - 1.7e-08 34.9 1.0 0.0013 19.3 0.0 2.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OAP55829.1 - 2.7e-06 27.3 3.1 0.0094 16.4 0.2 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 OAP55829.1 - 2.7e-06 27.6 2.7 0.00025 21.4 0.3 3.7 2 1 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 OAP55829.1 - 3.1e-05 24.2 1.8 0.00011 22.4 0.2 2.8 3 0 0 3 3 3 1 Ankyrin repeats (many copies) KilA-N PF04383.13 OAP55829.1 - 6.2e-05 22.8 0.2 0.00043 20.1 0.2 2.2 1 1 0 1 1 1 1 KilA-N domain TMF_TATA_bd PF12325.8 OAP55829.1 - 0.00066 19.9 3.4 0.00066 19.9 3.4 2.7 3 0 0 3 3 3 1 TATA element modulatory factor 1 TATA binding DUF4201 PF13870.6 OAP55829.1 - 0.13 12.0 4.7 0.3 10.8 4.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) Tup_N PF08581.10 OAP55829.1 - 0.15 12.4 6.8 0.71 10.2 0.7 3.2 3 0 0 3 3 3 0 Tup N-terminal FliJ PF02050.16 OAP55829.1 - 4 7.7 9.3 0.6 10.3 4.7 2.0 2 0 0 2 2 2 0 Flagellar FliJ protein ADH_zinc_N_2 PF13602.6 OAP55831.1 - 1.9e-19 71.1 0.0 3.3e-19 70.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 OAP55831.1 - 3.7e-17 62.5 0.0 8.5e-17 61.4 0.0 1.6 1 1 1 2 2 2 1 Zinc-binding dehydrogenase Acetyltransf_10 PF13673.7 OAP55832.1 - 0.052 13.5 0.0 0.088 12.8 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Ribonuclease_3 PF00636.26 OAP55833.1 - 4.4e-37 126.9 0.0 1.5e-21 76.9 0.0 2.8 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 OAP55833.1 - 4.5e-26 91.5 0.0 2.1e-15 57.0 0.0 3.8 3 1 0 3 3 3 3 Ribonuclease-III-like Dicer_dimer PF03368.14 OAP55833.1 - 3.7e-25 87.9 0.1 9.6e-25 86.6 0.1 1.8 1 0 0 1 1 1 1 Dicer dimerisation domain DEAD PF00270.29 OAP55833.1 - 5.2e-17 62.2 0.0 1.1e-16 61.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAP55833.1 - 4e-15 56.1 0.1 8.8e-15 55.0 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAP55833.1 - 1.9e-10 41.0 0.0 3.2e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit dsrm PF00035.26 OAP55833.1 - 0.0035 18.0 0.0 0.87 10.3 0.0 2.8 2 0 0 2 2 2 1 Double-stranded RNA binding motif Piwi PF02171.17 OAP55834.1 - 4.8e-71 239.5 0.0 1e-70 238.4 0.0 1.6 1 1 0 1 1 1 1 Piwi domain ArgoN PF16486.5 OAP55834.1 - 2.7e-14 54.0 0.1 4.9e-14 53.1 0.1 1.5 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 OAP55834.1 - 6.7e-13 48.1 0.1 4.2e-12 45.5 0.1 2.4 2 0 0 2 2 2 1 Argonaute linker 1 domain ArgoL2 PF16488.5 OAP55834.1 - 4.9e-12 46.0 0.0 1.9e-11 44.1 0.0 2.1 2 0 0 2 2 2 1 Argonaute linker 2 domain PAZ PF02170.22 OAP55834.1 - 7.5e-08 32.3 0.0 2.3e-07 30.7 0.0 1.8 1 0 0 1 1 1 1 PAZ domain ArgoMid PF16487.5 OAP55834.1 - 0.014 15.7 0.1 0.036 14.3 0.1 1.7 2 0 0 2 2 2 0 Mid domain of argonaute Mntp PF02659.15 OAP55834.1 - 0.14 11.9 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 Putative manganese efflux pump Hydrophobin PF01185.18 OAP55835.1 - 9.3e-09 35.8 12.5 1.5e-08 35.1 12.5 1.4 1 0 0 1 1 1 1 Fungal hydrophobin WD40 PF00400.32 OAP55836.1 - 6.5e-69 226.2 25.9 4.8e-10 39.9 0.3 8.0 6 1 1 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAP55836.1 - 1.5e-16 60.5 0.2 0.021 15.1 0.0 6.4 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OAP55836.1 - 6.2e-16 58.3 5.2 0.12 11.3 0.0 6.8 1 1 6 7 7 7 6 WD40 region of Ge1, enhancer of mRNA-decapping protein NACHT PF05729.12 OAP55836.1 - 5.9e-10 39.3 0.0 1.4e-09 38.1 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 OAP55836.1 - 1.6e-07 31.9 0.2 1.6e-07 31.9 0.2 2.8 3 0 0 3 3 3 1 AAA ATPase domain WD40_like PF17005.5 OAP55836.1 - 2.1e-07 30.6 1.2 0.03 13.7 0.0 4.0 4 0 0 4 4 4 2 WD40-like domain Nup160 PF11715.8 OAP55836.1 - 7.7e-07 28.1 16.8 0.18 10.4 0.1 6.4 2 1 5 7 7 7 4 Nucleoporin Nup120/160 IKI3 PF04762.12 OAP55836.1 - 2.1e-05 22.8 0.2 1.6 6.6 0.0 4.0 1 1 4 5 5 5 3 IKI3 family Robl_LC7 PF03259.17 OAP55836.1 - 3.1e-05 23.7 4.0 4.4 7.1 0.1 6.1 3 2 3 6 6 6 2 Roadblock/LC7 domain NACHT_N PF17100.5 OAP55836.1 - 5.9e-05 23.0 0.2 0.00012 22.1 0.2 1.4 1 0 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase AAA_22 PF13401.6 OAP55836.1 - 0.0025 18.1 0.0 0.011 15.9 0.0 2.1 1 0 0 1 1 1 1 AAA domain SMP_2 PF10144.9 OAP55836.1 - 0.0033 17.1 0.0 2.6 7.7 0.0 3.7 2 1 2 4 4 4 1 Bacterial virulence factor haemolysin PALB2_WD40 PF16756.5 OAP55836.1 - 0.007 15.3 2.4 11 4.8 0.1 4.2 2 1 3 5 5 5 0 Partner and localizer of BRCA2 WD40 domain AAA_30 PF13604.6 OAP55836.1 - 0.029 14.1 0.0 0.088 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 OAP55836.1 - 0.052 14.0 0.0 0.19 12.1 0.0 2.0 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 OAP55836.1 - 0.061 13.5 0.1 0.95 9.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 OAP55836.1 - 0.061 13.7 0.0 0.16 12.4 0.0 1.7 1 0 0 1 1 1 0 RNA helicase PD40 PF07676.12 OAP55836.1 - 0.067 13.2 20.1 30 4.7 0.2 7.6 7 1 1 8 8 8 0 WD40-like Beta Propeller Repeat CbiA PF01656.23 OAP55836.1 - 0.088 12.9 0.1 0.25 11.4 0.1 1.8 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain APS_kinase PF01583.20 OAP55836.1 - 0.13 12.2 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase Cytochrom_B562 PF07361.11 OAP55836.1 - 0.17 12.5 0.0 0.43 11.3 0.0 1.6 1 0 0 1 1 1 0 Cytochrome b562 Abhydrolase_3 PF07859.13 OAP55837.1 - 9.9e-33 113.8 0.0 1.3e-32 113.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 OAP55837.1 - 7.5e-07 28.4 0.0 1.3e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family Chlorophyllase2 PF12740.7 OAP55837.1 - 0.039 12.9 0.0 0.057 12.3 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Abhydrolase_2 PF02230.16 OAP55837.1 - 0.049 13.4 0.0 0.074 12.8 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase DUF2974 PF11187.8 OAP55837.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Esterase PF00756.20 OAP55837.1 - 0.12 12.0 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 Putative esterase adh_short_C2 PF13561.6 OAP55838.1 - 5.9e-48 163.5 0.0 7.9e-48 163.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP55838.1 - 9.5e-41 139.4 0.0 1.2e-40 139.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAP55838.1 - 3.1e-09 37.0 0.0 1.9e-08 34.4 0.0 1.8 2 0 0 2 2 2 1 KR domain THF_DHG_CYH_C PF02882.19 OAP55838.1 - 0.089 12.1 0.0 0.24 10.7 0.0 1.7 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ING PF12998.7 OAP55839.1 - 6.5e-09 36.3 1.4 2.7e-07 31.1 0.3 2.7 2 1 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 OAP55839.1 - 1.3e-05 25.0 8.5 2.2e-05 24.2 8.5 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 OAP55839.1 - 0.039 13.5 3.3 0.074 12.6 3.3 1.4 1 0 0 1 1 1 0 PHD-finger zf-HC5HC2H PF13771.6 OAP55839.1 - 0.29 11.4 1.9 0.63 10.3 1.9 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain Drf_GBD PF06371.13 OAP55840.1 - 1e-12 48.0 0.7 2.9e-10 40.0 0.7 2.3 1 1 0 1 1 1 1 Diaphanous GTPase-binding Domain NCD1 PF04904.13 OAP55840.1 - 0.17 11.9 0.1 0.42 10.6 0.1 1.6 1 1 0 1 1 1 0 NAB conserved region 1 (NCD1) Sugar_tr PF00083.24 OAP55842.1 - 7.8e-38 130.5 25.0 9.8e-37 126.9 25.0 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP55842.1 - 1.4e-30 106.4 31.7 5.2e-23 81.5 18.0 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily ORC5_C PF14630.6 OAP55843.1 - 0.0067 16.0 0.0 0.0081 15.7 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus HBM PF16591.5 OAP55843.1 - 0.038 13.4 0.1 0.049 13.0 0.1 1.1 1 0 0 1 1 1 0 Helical bimodular sensor domain Mito_carr PF00153.27 OAP55845.1 - 6.7e-56 186.2 2.1 5.2e-20 71.2 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 OAP55845.1 - 0.058 12.5 10.2 3.5 6.7 0.4 4.0 2 2 1 4 4 4 0 Gammaproteobacterial serine protease PT-VENN PF04829.13 OAP55845.1 - 1.9 8.6 6.3 24 5.1 0.0 3.6 4 0 0 4 4 4 0 Pre-toxin domain with VENN motif SWIRM PF04433.17 OAP55846.1 - 1.8e-31 108.3 0.1 4.2e-31 107.1 0.1 1.7 1 0 0 1 1 1 1 SWIRM domain SWIRM-assoc_1 PF16495.5 OAP55846.1 - 6.5e-30 102.9 9.1 1.6e-29 101.6 9.1 1.7 1 0 0 1 1 1 1 SWIRM-associated region 1 Myb_DNA-binding PF00249.31 OAP55846.1 - 1.4e-11 44.4 0.1 2.7e-11 43.5 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OAP55846.1 - 1.5e-07 31.5 0.0 3.1e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OAP55846.1 - 0.033 14.1 0.6 0.14 12.0 0.0 2.2 2 0 0 2 2 2 0 Myb DNA-binding like AAA_9 PF12781.7 OAP55846.1 - 0.13 11.3 1.1 0.24 10.5 1.1 1.3 1 0 0 1 1 1 0 ATP-binding dynein motor region ZZ PF00569.17 OAP55846.1 - 7.6 6.4 8.1 0.13 12.1 0.3 1.9 2 0 0 2 2 2 0 Zinc finger, ZZ type BTB PF00651.31 OAP55847.1 - 7.6e-06 26.1 0.0 2.5e-05 24.4 0.0 1.8 1 1 1 2 2 2 1 BTB/POZ domain AAA PF00004.29 OAP55848.1 - 3.4e-12 46.9 0.0 8.3e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OAP55848.1 - 7.3e-07 29.5 0.0 7.3e-06 26.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 OAP55848.1 - 1.4e-05 25.1 0.4 0.00017 21.6 0.4 2.3 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 OAP55848.1 - 1.4e-05 25.5 0.1 0.00061 20.2 0.0 3.1 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 OAP55848.1 - 2e-05 24.6 0.0 5.6e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 OAP55848.1 - 0.0001 22.1 0.0 0.0002 21.2 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 OAP55848.1 - 0.00075 19.5 0.0 0.0016 18.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 OAP55848.1 - 0.00085 19.5 0.0 0.0021 18.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 OAP55848.1 - 0.018 14.8 0.1 0.041 13.6 0.1 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 OAP55848.1 - 0.02 14.2 0.0 0.043 13.1 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.6 OAP55848.1 - 0.049 14.2 0.0 0.15 12.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 OAP55848.1 - 0.061 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 NTPase AAA_24 PF13479.6 OAP55848.1 - 0.091 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 OAP55848.1 - 0.14 12.5 0.1 0.73 10.2 0.0 2.1 3 0 0 3 3 2 0 AAA domain ABC_membrane_2 PF06472.15 OAP55849.1 - 9e-104 346.6 1.8 1.4e-103 346.0 1.8 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 OAP55849.1 - 1.8e-18 67.4 0.0 5e-18 65.9 0.0 1.8 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 OAP55849.1 - 5.5e-05 23.1 0.2 0.00014 21.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 OAP55849.1 - 0.0053 17.3 1.0 0.0053 17.3 1.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.6 OAP55849.1 - 0.017 14.9 0.0 0.037 13.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain SMC_N PF02463.19 OAP55849.1 - 0.022 14.2 1.2 0.14 11.6 0.1 2.4 2 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain Reticulon PF02453.17 OAP55849.1 - 0.027 14.4 0.4 0.19 11.7 0.4 2.2 1 1 0 1 1 1 0 Reticulon AAA_27 PF13514.6 OAP55849.1 - 0.073 12.6 1.2 0.48 10.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.12 OAP55849.1 - 0.082 12.7 0.3 1.4 8.6 0.0 2.9 4 0 0 4 4 4 0 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 OAP55849.1 - 0.11 12.4 0.1 0.27 11.1 0.1 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_15 PF13175.6 OAP55849.1 - 0.15 11.8 0.4 0.43 10.2 0.1 1.9 2 0 0 2 2 2 0 AAA ATPase domain Mg_chelatase PF01078.21 OAP55849.1 - 0.15 11.4 0.0 0.29 10.5 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Hemerythrin PF01814.23 OAP55851.1 - 1.8e-06 28.6 0.2 3.6e-06 27.6 0.2 1.4 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain HAD_2 PF13419.6 OAP55852.1 - 3.3e-09 37.1 0.0 4.5e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OAP55852.1 - 7.3e-09 36.2 0.0 5.1e-08 33.5 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Chitin_synth_2 PF03142.15 OAP55855.1 - 9.7e-231 766.9 0.0 1.2e-230 766.6 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase DEK_C PF08766.11 OAP55855.1 - 3.9e-15 55.5 0.1 1.6e-14 53.6 0.2 2.0 2 0 0 2 2 2 1 DEK C terminal domain Cyt-b5 PF00173.28 OAP55855.1 - 5.3e-14 52.1 0.3 3.7e-09 36.6 0.0 2.8 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_tranf_2_3 PF13641.6 OAP55855.1 - 8.1e-12 45.5 0.0 3e-11 43.6 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 OAP55855.1 - 2.6e-11 43.8 2.4 2.6e-11 43.8 2.4 2.0 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Myosin_head PF00063.21 OAP55855.1 - 1.5e-07 30.1 0.0 4.2e-07 28.6 0.0 1.6 2 0 0 2 2 2 1 Myosin head (motor domain) Glyco_transf_21 PF13506.6 OAP55855.1 - 0.00042 19.8 0.0 0.0012 18.3 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 OAP55855.1 - 0.0054 16.5 0.0 0.65 9.8 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 Csm4_C PF17953.1 OAP55855.1 - 0.15 11.9 0.0 0.56 10.1 0.0 1.9 1 0 0 1 1 1 0 CRISPR Csm4 C-terminal domain Chitin_synth_2 PF03142.15 OAP55856.1 - 1.4e-247 822.5 1.0 1.8e-247 822.1 1.0 1.1 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 OAP55856.1 - 2.3e-74 250.9 0.0 1.1e-73 248.6 0.0 1.8 1 1 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.28 OAP55856.1 - 5.2e-17 61.8 0.0 1.5e-13 50.7 0.0 3.4 3 0 0 3 3 3 2 Cytochrome b5-like Heme/Steroid binding domain DEK_C PF08766.11 OAP55856.1 - 2.6e-14 52.9 0.7 6.8e-14 51.5 0.7 1.8 1 0 0 1 1 1 1 DEK C terminal domain Glyco_trans_2_3 PF13632.6 OAP55856.1 - 2.1e-12 47.4 4.4 4.9e-12 46.2 4.4 1.7 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 OAP55856.1 - 3e-11 43.6 0.1 7.7e-10 39.0 0.1 2.6 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 OAP55856.1 - 1.2e-05 25.2 0.0 0.012 15.4 0.0 2.8 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 OAP55856.1 - 0.018 14.6 0.5 0.21 11.0 0.2 2.7 2 1 0 2 2 2 0 Glycosyl transferase family 21 AAA_22 PF13401.6 OAP55856.1 - 0.023 15.0 0.0 0.1 12.9 0.0 2.1 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 OAP55856.1 - 0.092 12.6 0.1 0.22 11.4 0.1 1.6 1 0 0 1 1 1 0 RsgA GTPase PLDc_2 PF13091.6 OAP55857.1 - 1e-18 67.5 0.4 6.4e-10 39.0 0.1 2.7 2 1 0 2 2 2 2 PLD-like domain PLDc PF00614.22 OAP55857.1 - 0.00024 21.2 0.5 0.037 14.2 0.0 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif Regulator_TrmB PF11495.8 OAP55857.1 - 0.0078 15.4 0.0 0.28 10.3 0.0 2.3 2 0 0 2 2 2 1 Archaeal transcriptional regulator TrmB PSDC PF12588.8 OAP55858.1 - 3.4e-42 143.8 0.0 5.7e-42 143.0 0.0 1.4 1 0 0 1 1 1 1 Phophatidylserine decarboxylase PS_Dcarbxylase PF02666.15 OAP55858.1 - 3.8e-39 134.3 0.0 5.4e-39 133.8 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase RnfC_N PF13375.6 OAP55858.1 - 0.0013 18.6 0.0 1.6 8.7 0.0 2.4 2 0 0 2 2 2 2 RnfC Barrel sandwich hybrid domain Peptidase_M23 PF01551.22 OAP55858.1 - 0.083 13.1 0.0 0.29 11.4 0.0 1.9 2 0 0 2 2 2 0 Peptidase family M23 PTS_EIIA_1 PF00358.20 OAP55858.1 - 0.2 11.4 0.0 0.37 10.6 0.0 1.3 1 0 0 1 1 1 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 TPP_enzyme_N PF02776.18 OAP55859.1 - 2.6e-37 128.1 0.0 7e-35 120.2 0.0 2.4 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 OAP55859.1 - 3e-20 72.5 0.0 5.7e-20 71.7 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 OAP55859.1 - 1.5e-10 40.9 0.0 7.5e-10 38.7 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain HET PF06985.11 OAP55860.1 - 4.2e-05 23.9 0.0 7.6e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF1518 PF07469.12 OAP55860.1 - 0.02 15.3 0.8 0.039 14.3 0.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1518) CHAT PF12770.7 OAP55861.1 - 1.4e-24 87.1 0.1 3.4e-24 85.7 0.1 1.7 2 0 0 2 2 2 1 CHAT domain TPR_2 PF07719.17 OAP55861.1 - 0.054 13.6 0.5 0.42 10.8 0.5 2.7 1 0 0 1 1 1 0 Tetratricopeptide repeat PNP_UDP_1 PF01048.20 OAP55862.1 - 7e-14 51.6 0.1 1.3e-13 50.8 0.1 1.4 1 0 0 1 1 1 1 Phosphorylase superfamily HSP70 PF00012.20 OAP55864.1 - 2.9e-05 22.5 0.1 7.1e-05 21.2 0.0 1.7 2 1 0 2 2 2 1 Hsp70 protein Sugar_tr PF00083.24 OAP55867.1 - 6.9e-119 397.7 23.0 7.9e-119 397.5 23.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP55867.1 - 2.3e-24 86.0 47.3 5.2e-20 71.7 23.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MCM PF00493.23 OAP55868.1 - 1.8e-97 324.9 0.3 3.7e-97 323.8 0.1 1.7 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 OAP55868.1 - 6.9e-31 106.7 0.0 1.6e-30 105.6 0.0 1.6 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 OAP55868.1 - 1.5e-24 86.2 3.1 3.3e-24 85.1 3.1 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 OAP55868.1 - 1.1e-11 45.2 0.0 3.2e-11 43.8 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 OAP55868.1 - 1.2e-06 28.1 0.0 1.4e-05 24.6 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 OAP55868.1 - 0.0034 17.2 0.0 0.013 15.4 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 OAP55868.1 - 0.094 12.4 0.0 0.25 11.0 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF3206 PF11472.8 OAP55870.1 - 0.015 15.2 0.6 0.21 11.6 0.2 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF3206) Transket_pyr PF02779.24 OAP55871.1 - 2.3e-65 219.6 0.0 3.9e-65 218.8 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 OAP55871.1 - 1.3e-58 198.3 0.0 2e-58 197.7 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 OAP55871.1 - 5.1e-57 191.8 0.1 1.4e-56 190.4 0.0 1.8 2 0 0 2 2 2 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 OAP55871.1 - 8.9e-21 73.2 1.4 1.9e-20 72.2 1.4 1.6 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus Glyco_hydro_17 PF00332.18 OAP55871.1 - 0.04 13.5 0.0 0.45 10.1 0.0 2.0 2 0 0 2 2 2 0 Glycosyl hydrolases family 17 DUF2680 PF10925.8 OAP55871.1 - 0.2 11.7 0.4 2.2 8.3 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2680) Nramp PF01566.18 OAP55873.1 - 1e-91 307.6 22.8 1e-91 307.6 22.8 1.5 2 0 0 2 2 2 1 Natural resistance-associated macrophage protein Thiolase_N PF00108.23 OAP55875.1 - 1.2e-76 257.5 1.9 1.2e-76 257.5 1.9 1.4 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 OAP55875.1 - 1.4e-41 141.0 0.0 2.6e-41 140.1 0.0 1.4 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 OAP55875.1 - 0.0071 16.0 2.2 0.25 10.9 1.0 3.1 2 1 1 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain Aldo_ket_red PF00248.21 OAP55877.1 - 1.3e-70 237.9 0.1 1.5e-70 237.7 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family RHH_1 PF01402.21 OAP55877.1 - 1.3 9.1 3.5 1.9 8.5 0.0 2.9 3 0 0 3 3 3 0 Ribbon-helix-helix protein, copG family Nodulin_late PF07127.11 OAP55878.1 - 0.021 15.1 12.1 1 9.7 0.3 3.2 3 0 0 3 3 3 0 Late nodulin protein Squash PF00299.18 OAP55878.1 - 1.2 9.2 28.1 2 8.5 3.7 3.4 3 0 0 3 3 3 0 Squash family serine protease inhibitor Gamma-thionin PF00304.20 OAP55878.1 - 8.5 6.7 35.4 3.3 8.0 6.0 3.4 3 0 0 3 3 3 0 Gamma-thionin family DIOX_N PF14226.6 OAP55879.1 - 1.7e-23 83.6 0.0 3.1e-23 82.8 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OAP55879.1 - 4.6e-21 75.2 0.0 1.5e-20 73.5 0.0 2.0 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily NAD_binding_8 PF13450.6 OAP55879.1 - 0.00083 19.5 0.1 0.0019 18.4 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DUF434 PF04256.12 OAP55879.1 - 0.11 12.2 0.2 0.32 10.7 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF434) bZIP_2 PF07716.15 OAP55880.1 - 1.2e-11 44.5 16.8 1.8e-11 44.0 16.8 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 OAP55880.1 - 2.5e-05 24.3 14.5 4e-05 23.6 14.5 1.4 1 0 0 1 1 1 1 bZIP transcription factor DUF3552 PF12072.8 OAP55880.1 - 0.0015 17.9 8.8 0.002 17.6 8.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) SHE3 PF17078.5 OAP55880.1 - 0.0022 17.7 2.7 0.0031 17.2 2.7 1.2 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 YabA PF06156.13 OAP55880.1 - 0.006 17.2 2.6 0.0091 16.6 2.6 1.3 1 0 0 1 1 1 1 Initiation control protein YabA Phage_T4_Ndd PF06591.11 OAP55880.1 - 0.028 14.2 0.0 0.038 13.8 0.0 1.2 1 0 0 1 1 1 0 T4-like phage nuclear disruption protein (Ndd) TSC22 PF01166.18 OAP55880.1 - 0.04 14.2 1.1 0.094 13.0 0.7 1.7 1 1 1 2 2 2 0 TSC-22/dip/bun family CBM-like PF14683.6 OAP55880.1 - 0.068 13.0 0.0 0.092 12.6 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide lyase family 4, domain III DUF4094 PF13334.6 OAP55880.1 - 0.13 12.7 0.8 0.2 12.1 0.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) Phlebovirus_NSM PF07246.11 OAP55880.1 - 0.15 11.4 4.8 0.19 11.1 4.8 1.1 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M FPP PF05911.11 OAP55880.1 - 0.24 9.6 9.0 0.31 9.2 9.0 1.0 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil XhlA PF10779.9 OAP55880.1 - 0.25 11.6 3.9 0.45 10.8 3.9 1.4 1 0 0 1 1 1 0 Haemolysin XhlA CMS1 PF14617.6 OAP55880.1 - 0.46 9.8 6.0 0.64 9.3 6.0 1.1 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit DivIC PF04977.15 OAP55880.1 - 2.3 8.0 7.4 2.4 8.0 6.5 1.5 1 1 0 1 1 1 0 Septum formation initiator Sulfatase PF00884.23 OAP55881.1 - 1.1e-65 222.0 0.2 1.7e-65 221.4 0.2 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 OAP55881.1 - 0.032 13.8 0.7 0.4 10.2 0.7 2.1 1 1 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase MFS_1 PF07690.16 OAP55882.1 - 6.9e-44 150.2 29.5 6.9e-44 150.2 29.5 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAP55882.1 - 3.2e-14 52.7 1.1 3.2e-14 52.7 1.1 2.6 3 1 0 3 3 3 1 Sugar (and other) transporter MFS_3 PF05977.13 OAP55882.1 - 7.6e-06 24.6 7.2 7.6e-06 24.6 7.2 2.0 2 1 0 2 2 2 1 Transmembrane secretion effector IMUP PF15761.5 OAP55882.1 - 0.23 12.2 5.2 0.51 11.0 5.2 1.5 1 0 0 1 1 1 0 Immortalisation up-regulated protein MFS_1 PF07690.16 OAP55883.1 - 3.1e-24 85.6 18.3 3.8e-24 85.3 18.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 OAP55883.1 - 0.23 11.2 5.4 0.054 13.2 1.7 1.9 2 0 0 2 2 2 0 Ion channel regulatory protein UNC-93 TauD PF02668.16 OAP55884.1 - 1.5e-46 159.3 0.0 2.1e-46 158.9 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DAG1 PF05454.11 OAP55884.1 - 0.14 11.5 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) GFA PF04828.14 OAP55885.1 - 3.4e-14 53.0 2.4 5.5e-09 36.3 0.2 3.6 4 1 0 4 4 4 2 Glutathione-dependent formaldehyde-activating enzyme zf_UBZ PF18439.1 OAP55885.1 - 0.072 12.7 0.9 9.5 5.9 0.1 2.6 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_2 PF13240.6 OAP55885.1 - 5.2 6.9 11.1 6.2 6.7 0.1 3.9 4 0 0 4 4 4 0 zinc-ribbon domain Sod_Fe_C PF02777.18 OAP55886.1 - 9.2e-37 125.3 0.5 9.2e-37 125.3 0.5 1.5 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 OAP55886.1 - 5.9e-29 100.4 1.5 1e-28 99.6 1.5 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain GCFC PF07842.12 OAP55887.1 - 1.1e-29 104.0 3.3 1.1e-29 104.0 3.3 1.7 2 0 0 2 2 2 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.23 OAP55887.1 - 1.2e-15 57.1 1.6 3e-15 55.8 1.6 1.7 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 OAP55887.1 - 0.054 13.6 0.8 0.054 13.6 0.8 2.7 2 0 0 2 2 2 0 G-patch domain adh_short_C2 PF13561.6 OAP55888.1 - 2.8e-56 190.7 1.6 4.3e-56 190.1 1.6 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP55888.1 - 1.6e-49 168.0 2.6 2.1e-49 167.7 2.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAP55888.1 - 2.7e-14 53.5 0.9 3.6e-14 53.1 0.9 1.1 1 0 0 1 1 1 1 KR domain DUF1372 PF07116.11 OAP55888.1 - 0.014 15.6 0.1 0.034 14.3 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1372) 3HCDH_N PF02737.18 OAP55888.1 - 0.12 12.2 1.0 0.29 11.0 1.0 1.6 1 1 1 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain CABS1 PF15367.6 OAP55888.1 - 0.16 11.1 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 Calcium-binding and spermatid-specific protein 1 DUF1741 PF08427.10 OAP55889.1 - 2.2e-73 246.8 0.7 3.3e-73 246.2 0.2 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1741) Fe-S_biosyn PF01521.20 OAP55890.1 - 6.4e-21 74.6 0.0 8.6e-21 74.2 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Dabb PF07876.12 OAP55891.1 - 1.3e-24 86.6 0.1 1.5e-24 86.5 0.1 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain cobW PF02492.19 OAP55892.1 - 3.6e-34 117.9 0.0 4.5e-34 117.6 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 OAP55892.1 - 2.2e-05 23.6 0.2 0.0042 16.1 0.1 2.1 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB PRK PF00485.18 OAP55892.1 - 0.0046 16.7 0.0 1.1 8.9 0.0 2.5 2 1 0 3 3 3 2 Phosphoribulokinase / Uridine kinase family MMR_HSR1 PF01926.23 OAP55892.1 - 0.016 15.2 0.0 0.058 13.5 0.0 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase CbiA PF01656.23 OAP55892.1 - 0.086 12.9 0.0 0.26 11.3 0.0 1.9 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_5 PF07728.14 OAP55892.1 - 0.086 12.8 0.0 0.2 11.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 OAP55892.1 - 0.17 11.8 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_23 PF13476.6 OAP55892.1 - 0.18 12.3 0.0 0.25 11.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 OAP55892.1 - 0.19 11.7 0.0 0.28 11.1 0.0 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit BING4CT PF08149.11 OAP55893.1 - 3.1e-40 135.8 0.6 2e-35 120.5 0.0 3.4 4 0 0 4 4 4 2 BING4CT (NUC141) domain ANAPC4_WD40 PF12894.7 OAP55893.1 - 1.4e-05 25.3 0.0 1.1 9.6 0.0 5.1 2 1 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OAP55893.1 - 6.1e-05 23.7 0.0 0.33 11.9 0.0 3.8 3 0 0 3 3 3 2 WD domain, G-beta repeat SPAM PF02090.15 OAP55893.1 - 0.014 15.2 9.5 0.037 13.8 9.5 1.7 1 0 0 1 1 1 0 Salmonella surface presentation of antigen gene type M protein COesterase PF00135.28 OAP55894.1 - 1.7e-90 304.3 0.2 2.3e-90 303.9 0.2 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAP55894.1 - 0.015 15.1 0.0 0.044 13.6 0.0 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold Esterase PF00756.20 OAP55894.1 - 0.073 12.7 0.1 0.14 11.8 0.1 1.4 1 0 0 1 1 1 0 Putative esterase Ank_2 PF12796.7 OAP55895.1 - 2.9e-13 50.2 1.0 9.3e-05 22.9 0.1 4.3 2 1 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAP55895.1 - 4.3e-08 33.6 1.7 0.078 13.6 0.0 4.7 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAP55895.1 - 8.6e-08 31.9 0.1 0.011 16.1 0.0 5.3 6 0 0 6 6 6 2 Ankyrin repeat Ank_5 PF13857.6 OAP55895.1 - 1e-05 25.7 1.0 0.82 10.1 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 OAP55895.1 - 0.00011 22.5 2.3 1 9.9 0.0 5.0 5 1 1 6 6 6 2 Ankyrin repeat SnoaL PF07366.12 OAP55896.1 - 0.0004 20.2 0.0 0.25 11.2 0.0 2.3 2 0 0 2 2 2 2 SnoaL-like polyketide cyclase DUF3176 PF11374.8 OAP55897.1 - 0.022 15.0 0.7 0.022 15.0 0.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3176) GFO_IDH_MocA PF01408.22 OAP55898.1 - 3.7e-22 79.4 0.1 8.1e-22 78.3 0.1 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 OAP55898.1 - 2e-07 31.0 0.0 3.6e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Toxin_R_bind_C PF07951.12 OAP55898.1 - 0.19 11.4 0.0 0.31 10.7 0.0 1.2 1 0 0 1 1 1 0 Clostridium neurotoxin, C-terminal receptor binding Fungal_trans_2 PF11951.8 OAP55899.1 - 1.3e-09 37.4 0.0 1.7e-07 30.4 0.0 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain DUF2457 PF10446.9 OAP55899.1 - 0.0075 15.5 2.8 0.014 14.6 2.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) Zn_clus PF00172.18 OAP55899.1 - 0.027 14.6 3.9 0.057 13.6 3.9 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.22 OAP55900.1 - 1.7e-58 198.5 0.0 2.4e-58 198.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Sugar_tr PF00083.24 OAP55901.1 - 8.4e-99 331.4 31.0 9.8e-99 331.2 31.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP55901.1 - 1.4e-30 106.4 30.4 1.4e-30 106.4 30.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Tox-MPTase3 PF15639.6 OAP55902.1 - 0.24 11.3 0.0 0.43 10.4 0.0 1.3 1 0 0 1 1 1 0 Metallopeptidase toxin 3 Acetyltransf_1 PF00583.25 OAP55903.1 - 3.5e-07 30.4 0.0 5.1e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OAP55903.1 - 5.4e-06 26.7 0.0 8.3e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OAP55903.1 - 3.8e-05 23.6 0.0 5e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAP55903.1 - 0.014 15.3 0.0 0.028 14.4 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Palm_thioest PF02089.15 OAP55904.1 - 3.8e-79 265.9 0.0 4.7e-79 265.6 0.0 1.1 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF915 PF06028.11 OAP55904.1 - 0.0043 16.4 0.0 0.0083 15.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) PGAP1 PF07819.13 OAP55904.1 - 0.0092 15.7 0.0 0.025 14.3 0.0 1.7 1 0 0 1 1 1 1 PGAP1-like protein Lipase_2 PF01674.18 OAP55904.1 - 0.02 14.4 0.0 0.13 11.8 0.0 2.0 1 1 0 1 1 1 0 Lipase (class 2) Glyco_hydro_16 PF00722.21 OAP55906.1 - 7.6e-12 45.1 0.0 1.5e-11 44.1 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 Methyltransf_16 PF10294.9 OAP55907.1 - 3.9e-20 72.3 0.0 4.6e-20 72.1 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 OAP55907.1 - 0.00082 18.9 0.0 0.0011 18.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 OAP55907.1 - 0.034 14.8 0.1 0.099 13.4 0.1 1.8 1 1 0 1 1 1 0 Methyltransferase domain GidB PF02527.15 OAP55907.1 - 0.035 13.4 0.0 0.052 12.9 0.0 1.2 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G NNMT_PNMT_TEMT PF01234.17 OAP55907.1 - 0.047 12.9 0.0 0.062 12.5 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family CxC1 PF18802.1 OAP55907.1 - 0.11 12.7 0.0 0.31 11.2 0.0 1.8 2 0 0 2 2 2 0 CxC1 like cysteine cluster associated with KDZ transposases Methyltransf_11 PF08241.12 OAP55907.1 - 0.17 12.6 0.0 0.41 11.3 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.15 OAP55907.1 - 0.2 11.3 0.0 0.64 9.6 0.0 1.7 2 0 0 2 2 2 0 Conserved hypothetical protein 95 KTI12 PF08433.10 OAP55909.1 - 1.3e-62 211.8 0.0 2.8e-62 210.6 0.0 1.6 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 OAP55909.1 - 1e-06 28.9 0.1 2.1e-06 27.9 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 OAP55909.1 - 0.0045 17.5 0.0 0.011 16.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain Ion_trans_2 PF07885.16 OAP55913.1 - 3.5e-29 100.6 24.6 6.2e-17 61.3 3.9 3.4 4 0 0 4 4 4 2 Ion channel Ion_trans PF00520.31 OAP55913.1 - 0.14 11.3 12.1 0.085 12.1 1.2 2.7 2 1 1 3 3 3 0 Ion transport protein DUF2207 PF09972.9 OAP55913.1 - 5.3 5.7 4.8 1.3 7.7 0.0 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF3669 PF12417.8 OAP55914.1 - 0.00021 21.4 0.1 0.00055 20.1 0.1 1.6 1 0 0 1 1 1 1 Zinc finger protein Stc1 PF12898.7 OAP55915.1 - 1.8e-16 60.5 14.0 2.5e-16 60.0 12.6 2.1 2 0 0 2 2 2 1 Stc1 domain Pkinase PF00069.25 OAP55916.1 - 2.8e-57 194.1 0.0 4.1e-57 193.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP55916.1 - 4.1e-31 108.2 0.0 1e-28 100.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 OAP55916.1 - 0.0021 17.1 0.0 0.0039 16.2 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Pox_ser-thr_kin PF05445.11 OAP55916.1 - 0.035 13.1 0.0 0.052 12.5 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase GTP_cyclohydro2 PF00925.20 OAP55918.1 - 5.2e-57 192.0 0.0 8.9e-56 188.0 0.0 2.0 1 1 0 1 1 1 1 GTP cyclohydrolase II DUF1325 PF07039.11 OAP55920.1 - 2.4e-21 76.2 1.2 4.1e-21 75.4 1.2 1.3 1 0 0 1 1 1 1 SGF29 tudor-like domain zf-C4H2 PF10146.9 OAP55920.1 - 0.0068 16.8 2.5 0.012 16.0 2.5 1.6 1 1 0 1 1 1 1 Zinc finger-containing protein RIB43A PF05914.12 OAP55920.1 - 0.007 15.2 0.7 0.011 14.5 0.7 1.3 1 0 0 1 1 1 1 RIB43A LBR_tudor PF09465.10 OAP55920.1 - 0.047 13.5 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain PMI_typeI PF01238.21 OAP55921.1 - 2.9e-136 454.5 0.0 3.4e-136 454.3 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I Talin_middle PF09141.10 OAP55921.1 - 0.024 14.6 0.5 0.043 13.8 0.5 1.3 1 0 0 1 1 1 0 Talin, middle domain Cupin_2 PF07883.11 OAP55921.1 - 0.086 12.6 0.0 4 7.2 0.0 2.3 2 0 0 2 2 2 0 Cupin domain p450 PF00067.22 OAP55922.1 - 2.5e-37 128.7 0.0 1.4e-25 90.0 0.0 3.0 2 1 0 2 2 2 2 Cytochrome P450 GFO_IDH_MocA PF01408.22 OAP55923.1 - 1.9e-21 77.1 0.0 3e-21 76.5 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 OAP55923.1 - 0.0018 18.9 0.2 0.0029 18.3 0.2 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain GFO_IDH_MocA_C PF02894.17 OAP55923.1 - 0.013 15.5 0.0 0.028 14.4 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain Cytochrom_C PF00034.21 OAP55924.1 - 1.4e-10 42.1 0.2 4.2e-10 40.6 0.0 1.8 2 0 0 2 2 2 1 Cytochrome c Cytochrome_CBB3 PF13442.6 OAP55924.1 - 3.2e-07 30.6 0.7 1.9e-06 28.1 0.7 2.0 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 OAP55924.1 - 0.0019 17.9 0.1 0.0083 15.8 0.1 1.9 2 0 0 2 2 2 1 Cytochrome c-550 domain Cytochrome-c551 PF10643.9 OAP55924.1 - 0.084 12.4 0.0 0.099 12.2 0.0 1.1 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 CRM1_C PF08767.11 OAP55925.1 - 0.21 10.7 1.2 2.5 7.2 0.1 2.1 2 0 0 2 2 2 0 CRM1 C terminal RNase_PH PF01138.21 OAP55926.1 - 2.6e-13 50.6 0.0 5.9e-13 49.5 0.0 1.6 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 OAP55926.1 - 0.0032 17.5 0.1 0.0062 16.5 0.1 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Spermine_synth PF01564.17 OAP55928.1 - 4.9e-71 238.0 0.0 8.1e-71 237.3 0.0 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 OAP55928.1 - 6.6e-24 83.6 0.1 1.1e-23 82.8 0.1 1.4 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 OAP55928.1 - 0.00078 20.1 0.0 0.0014 19.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAP55928.1 - 0.026 15.2 0.4 0.12 13.1 0.0 2.3 3 0 0 3 3 3 0 Methyltransferase domain Methyltransf_18 PF12847.7 OAP55928.1 - 0.027 14.4 0.0 0.049 13.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DUF43 PF01861.16 OAP55928.1 - 0.044 13.0 0.0 0.068 12.4 0.0 1.2 1 0 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain Myb_DNA-binding PF00249.31 OAP55928.1 - 0.15 12.3 0.1 0.4 10.9 0.1 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain TRI12 PF06609.13 OAP55929.1 - 2.5e-37 128.6 22.2 3.3e-37 128.2 22.2 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAP55929.1 - 2e-23 82.9 49.9 5.3e-23 81.5 48.4 2.2 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAP55929.1 - 1.8e-09 37.0 11.4 1.8e-09 37.0 11.4 3.4 3 1 1 4 4 4 1 Sugar (and other) transporter CcmE PF03100.15 OAP55929.1 - 0.15 12.1 0.1 1.4 8.9 0.1 2.5 2 0 0 2 2 2 0 CcmE Phage_holin_3_5 PF16085.5 OAP55929.1 - 0.42 10.8 6.2 11 6.3 0.0 3.4 3 0 0 3 3 3 0 Bacteriophage holin Hol, superfamily III p450 PF00067.22 OAP55930.1 - 3.3e-66 223.9 0.0 3.8e-66 223.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Molybdopterin PF00384.22 OAP55930.1 - 0.049 12.6 0.0 0.07 12.1 0.0 1.2 1 0 0 1 1 1 0 Molybdopterin oxidoreductase CHAT PF12770.7 OAP55931.1 - 3.5e-38 131.7 0.2 6.6e-38 130.8 0.2 1.5 1 0 0 1 1 1 1 CHAT domain TPR_10 PF13374.6 OAP55931.1 - 4.1e-07 29.7 2.7 0.42 10.6 0.5 6.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 OAP55931.1 - 0.00026 20.9 8.2 2.8 8.3 0.1 6.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 OAP55931.1 - 0.00047 20.1 6.9 17 6.0 0.0 6.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_12 PF13424.6 OAP55931.1 - 0.00068 19.9 17.0 1.5 9.2 0.4 7.7 7 1 1 8 8 8 1 Tetratricopeptide repeat SOAR PF16533.5 OAP55931.1 - 0.0017 18.3 0.1 0.7 9.9 0.0 2.9 2 0 0 2 2 2 1 STIM1 Orai1-activating region VWA_2 PF13519.6 OAP55931.1 - 0.013 16.1 0.3 77 4.0 0.0 4.9 4 1 0 5 5 5 0 von Willebrand factor type A domain TPR_1 PF00515.28 OAP55931.1 - 0.1 12.5 5.5 2.1 8.3 0.2 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 OAP55931.1 - 0.38 10.9 9.1 6 7.1 0.0 6.2 7 1 0 7 7 7 0 Tetratricopeptide repeat Peptidase_C14 PF00656.22 OAP55932.1 - 2.2e-18 67.2 0.0 3.6e-18 66.4 0.0 1.3 1 0 0 1 1 1 1 Caspase domain Peptidase_C13 PF01650.18 OAP55932.1 - 0.017 14.6 0.1 0.3 10.6 0.1 2.1 1 1 0 1 1 1 0 Peptidase C13 family Mus7 PF09462.10 OAP55934.1 - 5.3e-23 81.8 0.7 2.8e-18 66.2 0.7 2.2 2 0 0 2 2 2 2 Mus7/MMS22 family PAPA-1 PF04795.12 OAP55936.1 - 8e-21 74.6 3.7 8e-21 74.6 3.7 3.7 3 1 0 3 3 3 1 PAPA-1-like conserved region RNA_pol_3_Rpc31 PF11705.8 OAP55936.1 - 0.0082 16.4 4.5 0.0082 16.4 4.5 4.5 4 1 0 4 4 4 1 DNA-directed RNA polymerase III subunit Rpc31 Pex14_N PF04695.13 OAP55937.1 - 1e-36 127.0 2.7 1e-36 127.0 2.7 3.2 2 1 1 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region adh_short PF00106.25 OAP55938.1 - 5.8e-41 140.1 3.1 9.4e-41 139.4 3.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP55938.1 - 7.4e-40 137.0 0.7 1.1e-39 136.5 0.7 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Ank_2 PF12796.7 OAP55938.1 - 3.8e-36 123.6 0.5 3.9e-15 56.2 0.0 3.5 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAP55938.1 - 4.9e-22 78.0 1.4 5.6e-14 52.3 0.0 6.1 5 2 2 8 8 8 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAP55938.1 - 1.5e-21 74.1 0.7 5.8e-05 23.2 0.0 6.3 6 0 0 6 6 6 3 Ankyrin repeat Ank PF00023.30 OAP55938.1 - 1.1e-19 69.9 8.4 6.1e-06 26.4 0.0 6.5 8 0 0 8 8 8 4 Ankyrin repeat Ank_5 PF13857.6 OAP55938.1 - 4.3e-19 68.3 0.3 1.5e-06 28.3 0.0 5.9 3 2 3 6 6 6 4 Ankyrin repeats (many copies) KR PF08659.10 OAP55938.1 - 8.1e-11 42.2 3.0 1.3e-10 41.5 3.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAP55938.1 - 0.00031 20.3 0.4 0.00062 19.3 0.4 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family ELFV_dehydrog PF00208.21 OAP55938.1 - 0.0055 16.4 0.1 0.0092 15.7 0.1 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase GDP_Man_Dehyd PF16363.5 OAP55938.1 - 0.016 14.6 0.4 0.11 11.8 0.4 2.0 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase VWA_3_C PF18571.1 OAP55938.1 - 0.033 14.1 0.3 6.5 6.7 0.1 3.8 4 0 0 4 4 4 0 von Willebrand factor type A C-terminal domain WGG PF10273.9 OAP55939.1 - 1.8e-24 86.2 0.6 3.4e-24 85.3 0.6 1.4 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 Nop25 PF09805.9 OAP55939.1 - 0.33 11.4 6.0 0.52 10.8 5.9 1.4 1 1 0 1 1 1 0 Nucleolar protein 12 (25kDa) SDA1 PF05285.12 OAP55939.1 - 0.48 9.8 12.1 0.54 9.6 12.1 1.1 1 0 0 1 1 1 0 SDA1 Cupin_2 PF07883.11 OAP55940.1 - 7.2e-16 57.7 0.0 1.2e-15 56.9 0.0 1.4 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 OAP55940.1 - 7e-06 26.0 0.0 1e-05 25.5 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.22 OAP55940.1 - 7.8e-05 22.3 0.0 0.00014 21.5 0.0 1.3 1 0 0 1 1 1 1 Cupin ARD PF03079.14 OAP55940.1 - 0.00033 20.9 0.7 0.00052 20.2 0.0 1.6 2 0 0 2 2 2 1 ARD/ARD' family Cupin_3 PF05899.12 OAP55940.1 - 0.0074 16.0 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF861) JmjC PF02373.22 OAP55940.1 - 0.029 14.8 0.0 0.048 14.1 0.0 1.3 1 0 0 1 1 1 0 JmjC domain, hydroxylase Cupin_6 PF12852.7 OAP55940.1 - 0.04 13.7 0.0 0.046 13.4 0.0 1.2 1 0 0 1 1 1 0 Cupin GPI PF06560.11 OAP55940.1 - 0.069 12.4 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) EutQ PF06249.12 OAP55940.1 - 0.095 12.5 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutQ FMO-like PF00743.19 OAP55941.1 - 2.4e-20 72.5 0.1 4.5e-18 65.0 0.0 2.4 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 OAP55941.1 - 8.9e-10 38.3 0.0 4.3e-07 29.5 0.0 2.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAP55941.1 - 4.3e-09 36.0 0.0 5.3e-05 22.5 0.0 3.2 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 OAP55941.1 - 1.1e-07 32.0 0.0 2.5e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 OAP55941.1 - 3.7e-05 23.1 0.0 0.00068 19.0 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAP55941.1 - 0.023 14.7 0.0 0.28 11.1 0.0 2.4 3 0 0 3 3 3 0 FAD-NAD(P)-binding Flavodoxin_1 PF00258.25 OAP55941.1 - 0.072 13.3 0.0 1.7 8.9 0.0 2.3 2 0 0 2 2 2 0 Flavodoxin Shikimate_DH PF01488.20 OAP55941.1 - 0.11 12.5 0.0 4.9 7.2 0.0 2.8 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Calcipressin PF04847.12 OAP55942.1 - 1.2e-35 122.9 0.3 2.5e-35 121.9 0.3 1.6 1 1 0 1 1 1 1 Calcipressin Mito_carr PF00153.27 OAP55943.1 - 4.6e-54 180.3 2.9 6.1e-20 70.9 0.3 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein tRNA-synt_2d PF01409.20 OAP55944.1 - 1.5e-47 162.2 0.2 6.1e-26 91.4 0.0 2.4 2 1 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 OAP55944.1 - 1.5e-25 89.4 0.0 4.7e-25 87.8 0.0 1.9 1 1 0 1 1 1 1 Ferredoxin-fold anticodon binding domain GrpE PF01025.19 OAP55945.1 - 7.8e-40 136.3 4.9 7e-39 133.2 4.9 1.9 1 1 0 1 1 1 1 GrpE Peptidase_S49 PF01343.18 OAP55945.1 - 0.04 13.9 0.6 0.07 13.1 0.6 1.4 1 0 0 1 1 1 0 Peptidase family S49 ALMS_motif PF15309.6 OAP55945.1 - 0.044 14.3 2.3 0.067 13.7 2.3 1.2 1 0 0 1 1 1 0 ALMS motif Pam16 PF03656.13 OAP55945.1 - 0.61 10.1 3.2 0.55 10.3 0.5 2.3 2 1 0 2 2 2 0 Pam16 GRP PF07172.11 OAP55946.1 - 0.00056 20.5 17.2 0.001 19.7 17.2 1.3 1 0 0 1 1 1 1 Glycine rich protein family ATE_C PF04377.15 OAP55947.1 - 6.6e-48 162.7 3.0 9.8e-48 162.2 3.0 1.3 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 OAP55947.1 - 2.9e-20 72.5 1.5 6.1e-20 71.4 1.5 1.6 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus Acetyltransf_6 PF13480.7 OAP55947.1 - 0.098 12.8 1.0 0.21 11.8 1.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain NUDIX PF00293.28 OAP55948.1 - 3.9e-18 65.8 0.3 4.7e-18 65.5 0.3 1.1 1 0 0 1 1 1 1 NUDIX domain DUF4913 PF16259.5 OAP55948.1 - 0.099 12.7 1.1 4.2 7.5 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4913) COX6B PF02297.17 OAP55949.1 - 8.3e-20 70.8 4.8 9.5e-20 70.6 4.8 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb CX9C PF16860.5 OAP55949.1 - 0.0083 16.1 1.7 0.013 15.5 1.7 1.3 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, APOBEC_C PF05240.14 OAP55949.1 - 0.012 15.6 0.1 0.015 15.2 0.1 1.3 1 0 0 1 1 1 0 APOBEC-like C-terminal domain RRM_1 PF00076.22 OAP55951.1 - 1.4e-13 50.4 0.0 2.2e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OAP55951.1 - 0.064 12.9 0.0 0.11 12.1 0.0 1.4 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 OAP55951.1 - 0.12 12.4 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif SRA1 PF07304.11 OAP55952.1 - 1.7e-07 31.2 0.0 1.7e-07 31.2 0.0 3.4 2 0 0 2 2 2 1 Steroid receptor RNA activator (SRA1) Sec16_C PF12931.7 OAP55952.1 - 0.0037 17.0 0.8 0.033 13.8 0.8 2.3 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 Prp18 PF02840.15 OAP55952.1 - 0.0044 17.1 0.0 0.01 15.9 0.0 1.6 1 0 0 1 1 1 1 Prp18 domain WD40 PF00400.32 OAP55952.1 - 0.014 16.3 0.2 0.014 16.3 0.2 5.4 7 0 0 7 7 7 0 WD domain, G-beta repeat GFO_IDH_MocA PF01408.22 OAP55953.1 - 8.2e-09 36.3 0.0 1.7e-08 35.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Ammonium_transp PF00909.21 OAP55954.1 - 1.5e-109 366.4 24.8 1.7e-109 366.2 24.8 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Gln-synt_C PF00120.24 OAP55955.1 - 1.6e-16 60.3 0.0 9.7e-13 47.8 0.0 2.2 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 OAP55955.1 - 8e-14 51.1 0.0 1.6e-13 50.2 0.0 1.5 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Glyco_transf_28 PF03033.20 OAP55956.1 - 1.2e-14 54.6 0.1 7.3e-14 52.0 0.1 2.1 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain ATG_C PF09333.11 OAP55956.1 - 3e-06 27.5 0.0 2.4e-05 24.6 0.0 2.4 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain UDPGT PF00201.18 OAP55956.1 - 6.2e-05 22.0 0.0 0.00011 21.1 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 OAP55956.1 - 0.00057 19.9 0.0 0.0014 18.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain HECT PF00632.25 OAP55958.1 - 8.1e-77 258.7 0.0 1.3e-76 258.1 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Arm PF00514.23 OAP55958.1 - 0.0053 16.8 12.9 12 6.1 0.0 6.8 7 1 1 8 8 8 2 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.20 OAP55958.1 - 0.023 13.3 2.7 1.1 7.8 0.0 3.2 3 0 0 3 3 3 0 Adaptin N terminal region RRN3 PF05327.11 OAP55958.1 - 8.9 4.7 15.1 2.8 6.4 7.7 2.5 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 CTP_transf_like PF01467.26 OAP55959.1 - 4.5e-26 91.8 0.0 6.1e-26 91.3 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase-like Ubie_methyltran PF01209.18 OAP55961.1 - 2.1e-75 253.1 0.0 2.3e-75 252.9 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 OAP55961.1 - 5.1e-17 62.4 0.0 1.1e-16 61.4 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAP55961.1 - 3.2e-14 53.0 0.0 3.8e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAP55961.1 - 8.7e-14 51.9 0.0 1.9e-13 50.9 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAP55961.1 - 2.7e-07 31.3 0.0 3.8e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAP55961.1 - 1.2e-06 28.4 0.0 1.7e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 OAP55961.1 - 0.0036 17.3 0.0 0.0044 17.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 OAP55961.1 - 0.11 12.3 0.0 0.64 9.8 0.0 2.0 2 0 0 2 2 2 0 Hypothetical methyltransferase E1_dh PF00676.20 OAP55962.1 - 3e-88 295.6 0.0 3.8e-88 295.3 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 OAP55962.1 - 0.0037 17.1 0.0 0.0099 15.7 0.0 1.7 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Glyco_hydro_16 PF00722.21 OAP55963.1 - 6.2e-42 143.1 3.1 6.2e-42 143.1 3.1 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 zf-C2H2_2 PF12756.7 OAP55964.1 - 2e-37 127.6 14.3 4.6e-31 107.2 2.8 3.5 2 1 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 OAP55964.1 - 3.9e-11 42.9 15.1 3.9e-08 33.4 1.1 4.2 4 1 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OAP55964.1 - 2.8e-07 30.7 1.2 2.8e-07 30.7 1.2 3.1 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 OAP55964.1 - 0.053 14.0 17.3 0.33 11.5 0.3 4.5 4 0 0 4 4 4 0 Zinc finger, C2H2 type Mso1_Sec1_bdg PF14475.6 OAP55964.1 - 0.16 11.6 1.1 0.47 10.1 0.7 2.0 2 0 0 2 2 2 0 Sec1-binding region of Mso1 zf-C2H2_4 PF13894.6 OAP55964.1 - 0.8 10.7 24.2 0.81 10.7 0.1 5.1 5 0 0 5 5 5 0 C2H2-type zinc finger Ribosomal_L33 PF00471.20 OAP55965.1 - 3.6e-06 27.3 0.0 4.2e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L33 DivIC PF04977.15 OAP55966.1 - 0.0065 16.2 7.8 0.0065 16.2 7.8 10.9 6 4 5 12 12 12 1 Septum formation initiator Spc7 PF08317.11 OAP55966.1 - 4 6.2 119.3 0.12 11.2 23.4 6.9 1 1 6 7 7 7 0 Spc7 kinetochore protein SKG6 PF08693.10 OAP55967.1 - 0.021 14.2 0.8 0.043 13.2 0.8 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain LapA_dom PF06305.11 OAP55967.1 - 0.058 13.2 1.0 0.058 13.2 1.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Insulin_TMD PF17870.1 OAP55967.1 - 0.08 13.0 0.1 0.17 12.0 0.1 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment SIT PF15330.6 OAP55967.1 - 0.19 12.1 0.2 1.2 9.6 0.2 2.2 2 1 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT zf-UBR PF02207.20 OAP55968.1 - 6.4e-19 67.9 11.8 1.8e-18 66.4 11.8 1.9 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 OAP55968.1 - 0.00011 22.0 0.1 0.00039 20.2 0.1 2.0 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS Acetyltransf_11 PF13720.6 OAP55968.1 - 0.16 12.4 0.2 0.87 10.1 0.0 2.4 2 0 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 UCR_UQCRX_QCR9 PF05365.12 OAP55969.1 - 4.4e-25 87.4 2.3 4.9e-25 87.2 2.3 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Arylsulfotran_2 PF14269.6 OAP55971.1 - 4.8e-41 141.1 0.1 6.8e-41 140.6 0.1 1.1 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 OAP55971.1 - 2.1e-12 46.7 0.1 8.6e-11 41.3 0.1 2.2 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) LRR19-TM PF15176.6 OAP55971.1 - 0.024 14.6 0.1 0.074 13.0 0.0 1.9 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain Mago-bind PF09282.10 OAP55972.1 - 3.7e-14 52.3 3.5 7.3e-14 51.3 3.5 1.5 1 0 0 1 1 1 1 Mago binding DUF5319 PF17252.2 OAP55972.1 - 4.8 7.4 5.0 2.3 8.5 1.1 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5319) Amino_oxidase PF01593.24 OAP55973.1 - 4e-24 85.7 0.1 1.7e-23 83.7 0.1 1.8 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OAP55973.1 - 3.1e-12 46.5 0.0 8.1e-12 45.2 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAP55973.1 - 2.1e-08 34.1 0.0 5.2e-06 26.3 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.17 OAP55973.1 - 1.6e-05 24.3 0.0 0.0082 15.4 0.0 2.2 2 0 0 2 2 2 2 Thi4 family Pyr_redox PF00070.27 OAP55973.1 - 0.00011 22.7 0.2 0.12 13.0 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAP55973.1 - 0.00022 20.5 0.0 0.012 14.8 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAP55973.1 - 0.0004 20.4 0.0 0.016 15.2 0.0 2.5 3 0 0 3 3 3 1 FAD-NAD(P)-binding MCRA PF06100.11 OAP55973.1 - 0.0017 17.2 0.1 0.0032 16.3 0.0 1.4 2 0 0 2 2 2 1 MCRA family Trp_halogenase PF04820.14 OAP55973.1 - 0.1 11.5 0.0 0.28 10.0 0.0 1.7 2 0 0 2 2 2 0 Tryptophan halogenase HI0933_like PF03486.14 OAP55973.1 - 0.14 10.8 0.0 1.5 7.4 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein FAD_oxidored PF12831.7 OAP55973.1 - 0.17 11.2 0.1 0.34 10.2 0.0 1.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase AA_permease PF00324.21 OAP55974.1 - 1.3e-125 419.8 34.5 1.4e-125 419.6 34.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAP55974.1 - 8.6e-33 113.8 37.7 1.2e-32 113.4 37.7 1.1 1 0 0 1 1 1 1 Amino acid permease Vps52 PF04129.12 OAP55975.1 - 2.5e-120 402.6 0.0 3.1e-120 402.3 0.0 1.0 1 0 0 1 1 1 1 Vps52 / Sac2 family Sec3_C PF09763.9 OAP55975.1 - 0.00019 20.0 3.7 0.00028 19.4 3.7 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec3 DUF812 PF05667.11 OAP55975.1 - 0.0059 15.6 0.0 0.0092 14.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF812) ATG16 PF08614.11 OAP55975.1 - 0.0068 16.7 0.3 0.02 15.1 0.3 1.8 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Mer2 PF09074.10 OAP55975.1 - 0.0071 16.2 1.2 0.22 11.3 0.2 2.4 2 0 0 2 2 2 1 Mer2 TBCC_N PF16752.5 OAP55975.1 - 0.012 16.0 2.3 0.02 15.4 0.3 2.4 2 0 0 2 2 2 0 Tubulin-specific chaperone C N-terminal domain THOC7 PF05615.13 OAP55975.1 - 0.019 15.2 0.3 0.019 15.2 0.3 2.0 2 0 0 2 2 2 0 Tho complex subunit 7 Laminin_II PF06009.12 OAP55975.1 - 0.18 11.8 1.7 0.35 10.9 0.2 2.2 3 0 0 3 3 3 0 Laminin Domain II Baculo_PEP_C PF04513.12 OAP55975.1 - 0.19 11.8 0.9 0.54 10.3 0.2 2.0 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 OAP55975.1 - 0.19 11.8 0.2 0.43 10.6 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) COG5 PF10392.9 OAP55975.1 - 0.2 11.8 3.1 1.4 9.1 0.3 2.7 2 0 0 2 2 2 0 Golgi transport complex subunit 5 BST2 PF16716.5 OAP55975.1 - 1.6 9.3 8.2 0.1 13.2 2.3 2.0 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 ADH_zinc_N PF00107.26 OAP55976.1 - 3.3e-23 82.1 1.6 3.3e-23 82.1 1.6 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAP55976.1 - 1.3e-22 79.7 2.9 3.3e-22 78.4 2.9 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 OAP55976.1 - 2.9e-07 31.6 0.0 6.4e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 OAP55976.1 - 5.9e-07 29.2 1.0 1.4e-06 27.9 1.1 1.5 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 OAP55976.1 - 0.012 14.9 4.2 0.012 14.9 4.2 1.7 2 1 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Aldedh PF00171.22 OAP55977.1 - 6e-132 440.4 1.3 6.8e-132 440.2 1.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 OAP55977.1 - 0.007 15.5 0.0 0.01 14.9 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) FAD_binding_3 PF01494.19 OAP55978.1 - 4.5e-23 82.1 0.0 1.6e-22 80.2 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 OAP55978.1 - 1.9e-07 30.5 2.8 8.9e-07 28.3 2.8 1.9 1 1 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 OAP55978.1 - 1.4e-06 27.8 0.6 1e-05 24.9 0.6 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAP55978.1 - 8.7e-05 22.7 2.1 0.00021 21.4 2.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 OAP55978.1 - 0.00057 19.2 1.8 0.0054 16.0 0.9 2.2 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.27 OAP55978.1 - 0.00072 20.1 0.1 0.0017 18.9 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAP55978.1 - 0.0014 17.4 0.1 0.0022 16.8 0.0 1.3 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 OAP55978.1 - 0.0021 17.2 4.0 0.0034 16.5 4.0 1.3 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.24 OAP55978.1 - 0.0027 17.1 0.4 0.77 9.0 0.3 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase DAO PF01266.24 OAP55978.1 - 0.0038 16.9 10.8 0.066 12.8 6.0 2.7 1 1 1 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 OAP55978.1 - 0.0045 16.3 0.3 0.015 14.6 0.3 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 OAP55978.1 - 0.0076 15.1 1.6 0.05 12.5 0.4 2.1 1 1 0 2 2 2 1 Tryptophan halogenase SE PF08491.10 OAP55978.1 - 0.044 12.8 0.0 0.072 12.1 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase Rossmann-like PF10727.9 OAP55978.1 - 0.046 13.6 0.5 0.14 12.1 0.5 1.7 1 0 0 1 1 1 0 Rossmann-like domain NAD_Gly3P_dh_N PF01210.23 OAP55978.1 - 0.05 13.6 0.1 0.098 12.6 0.1 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.18 OAP55978.1 - 0.052 13.4 0.0 0.16 11.9 0.1 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 OAP55978.1 - 0.094 12.0 1.8 0.17 11.2 1.8 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Hexapep_2 PF14602.6 OAP55978.1 - 0.21 11.4 0.1 0.21 11.4 0.1 2.0 2 0 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase GIDA PF01134.22 OAP55978.1 - 0.46 9.5 4.2 0.8 8.7 4.2 1.5 1 1 0 1 1 1 0 Glucose inhibited division protein A MFS_1 PF07690.16 OAP55979.1 - 3.1e-29 102.0 39.9 3.1e-29 102.0 39.9 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily p450 PF00067.22 OAP55980.1 - 7.1e-66 222.8 0.0 8.7e-66 222.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SnoaL_4 PF13577.6 OAP55981.1 - 5.1e-08 33.1 0.4 1.5e-07 31.6 0.4 1.7 1 1 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 OAP55981.1 - 0.0092 16.4 0.7 0.014 15.8 0.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_2 PF12680.7 OAP55981.1 - 0.053 14.2 1.5 0.09 13.4 1.5 1.4 1 0 0 1 1 1 0 SnoaL-like domain Fungal_trans PF04082.18 OAP55982.1 - 5.4e-29 101.0 0.4 1e-28 100.1 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Lactamase_B PF00753.27 OAP55983.1 - 1.4e-11 44.8 1.9 2.1e-11 44.2 1.9 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OAP55983.1 - 0.0028 17.2 0.0 0.0057 16.2 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DSBA PF01323.20 OAP55984.1 - 4.4e-49 166.9 0.0 6.7e-26 91.3 0.0 3.0 2 1 0 2 2 2 2 DSBA-like thioredoxin domain Thioredoxin_5 PF13743.6 OAP55984.1 - 0.0017 18.1 0.0 0.0039 16.9 0.0 1.5 2 0 0 2 2 2 1 Thioredoxin EspA PF03433.13 OAP55984.1 - 0.14 12.0 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 EspA-like secreted protein Methyltransf_23 PF13489.6 OAP55985.1 - 1e-22 80.7 0.0 1.9e-22 79.9 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAP55985.1 - 2.1e-11 44.4 0.0 5.6e-11 43.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAP55985.1 - 1.2e-09 38.8 0.0 7.4e-09 36.3 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAP55985.1 - 3e-09 36.8 0.0 3.7e-08 33.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAP55985.1 - 9.1e-09 35.9 0.0 1.8e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 OAP55985.1 - 0.00091 18.7 0.0 0.0016 17.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 OAP55985.1 - 0.00096 18.7 0.0 0.0036 16.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_4 PF02390.17 OAP55985.1 - 0.0043 16.5 0.0 0.034 13.6 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase Ubie_methyltran PF01209.18 OAP55985.1 - 0.0068 15.8 0.0 3.9 6.7 0.0 2.8 3 0 0 3 3 3 2 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.9 OAP55985.1 - 0.017 14.9 0.0 0.027 14.2 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase DUF938 PF06080.12 OAP55985.1 - 0.035 13.9 0.0 0.057 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) p450 PF00067.22 OAP55986.1 - 3.4e-53 181.0 0.0 4.5e-53 180.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 eIF-5a PF01287.20 OAP55987.1 - 2.7e-29 101.1 1.1 3.7e-29 100.6 1.1 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 OAP55987.1 - 0.0015 18.5 0.3 0.021 14.8 0.0 2.3 2 0 0 2 2 2 1 Elongation factor P (EF-P) KOW-like domain Response_reg PF00072.24 OAP55987.1 - 0.091 12.9 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 Response regulator receiver domain zf-RRN7 PF11781.8 OAP55988.1 - 2.7e-06 27.0 3.3 4.3e-06 26.3 3.3 1.3 1 0 0 1 1 1 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Rhodanese PF00581.20 OAP55989.1 - 1.1e-09 38.7 0.0 1.8e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain APH PF01636.23 OAP55990.1 - 0.055 13.4 1.3 0.11 12.4 0.3 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family adh_short PF00106.25 OAP55992.1 - 2.2e-16 59.9 0.0 6.3e-15 55.1 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP55992.1 - 8.3e-09 35.3 0.0 1.4e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP55992.1 - 0.00025 21.0 0.1 0.00036 20.5 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAP55992.1 - 0.012 15.1 0.0 0.024 14.1 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Vanabin-2 PF11437.8 OAP55992.1 - 0.063 13.4 0.9 0.11 12.7 0.2 1.7 2 0 0 2 2 2 0 Vanadium-binding protein 2 p450 PF00067.22 OAP55993.1 - 1.5e-75 254.8 0.0 1.8e-75 254.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Abhydrolase_6 PF12697.7 OAP55994.1 - 1.1e-15 58.8 9.2 1.3e-15 58.6 9.2 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAP55994.1 - 0.0032 16.8 0.0 0.47 9.7 0.0 2.8 3 0 0 3 3 3 2 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 OAP55994.1 - 0.06 12.3 0.0 0.079 11.9 0.0 1.1 1 0 0 1 1 1 0 Chlorophyllase enzyme Sec7 PF01369.20 OAP55995.1 - 5.7e-31 107.6 0.0 8.9e-31 107.0 0.0 1.2 1 0 0 1 1 1 1 Sec7 domain PH PF00169.29 OAP55995.1 - 1.5e-07 31.9 0.7 6e-07 29.9 0.7 2.1 1 1 0 1 1 1 1 PH domain PH_9 PF15410.6 OAP55995.1 - 1.8e-06 28.3 0.1 4.4e-06 27.1 0.1 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain Dicty_REP PF05086.12 OAP55995.1 - 0.37 8.7 1.2 0.77 7.7 1.2 1.4 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein PH PF00169.29 OAP55996.1 - 5.3e-05 23.7 0.0 0.00022 21.7 0.0 2.1 2 0 0 2 2 2 1 PH domain PH_9 PF15410.6 OAP55996.1 - 0.00032 21.0 0.0 0.0011 19.3 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain Zn_clus PF00172.18 OAP55997.1 - 2.5e-07 30.7 9.6 3.8e-07 30.1 9.6 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SSrecog PF03531.14 OAP55998.1 - 2.5e-29 101.0 0.0 9.5e-29 99.1 0.0 2.1 1 0 0 1 1 1 1 Structure-specific recognition protein (SSRP1) POB3_N PF17292.2 OAP55998.1 - 2.5e-29 101.5 0.1 7.7e-28 96.8 0.0 2.7 3 0 0 3 3 3 1 POB3-like N-terminal PH domain Rtt106 PF08512.12 OAP55998.1 - 1.1e-25 89.9 0.0 7.6e-25 87.1 0.0 2.3 2 0 0 2 2 2 1 Histone chaperone Rttp106-like DUF4974 PF16344.5 OAP55998.1 - 0.017 15.1 0.7 6.1 6.9 0.0 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4974) CBS PF00571.28 OAP55999.1 - 1.2e-35 121.7 4.2 4.5e-09 36.6 0.0 5.2 5 0 0 5 5 5 4 CBS domain PB1 PF00564.24 OAP55999.1 - 3.9e-11 42.7 0.1 1.5e-10 40.9 0.0 2.1 2 0 0 2 2 2 1 PB1 domain AAA PF00004.29 OAP56000.1 - 2.4e-56 189.8 0.0 2.6e-43 147.6 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.11 OAP56000.1 - 2.9e-28 98.1 1.9 6.6e-28 96.9 1.7 1.8 2 0 0 2 2 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_lid_3 PF17862.1 OAP56000.1 - 1.1e-13 50.7 0.0 1.6e-07 31.0 0.0 2.6 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 OAP56000.1 - 4.3e-10 40.2 6.9 0.00022 21.6 0.1 4.8 3 2 1 5 5 5 2 AAA ATPase domain AAA_2 PF07724.14 OAP56000.1 - 9.5e-09 35.6 0.0 0.00083 19.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) NACHT PF05729.12 OAP56000.1 - 3.7e-06 27.0 0.1 0.0028 17.6 0.0 3.1 3 0 0 3 3 3 1 NACHT domain RuvB_N PF05496.12 OAP56000.1 - 1.1e-05 25.2 0.0 0.015 15.1 0.0 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 OAP56000.1 - 1.2e-05 24.7 0.0 0.012 14.8 0.0 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_5 PF07728.14 OAP56000.1 - 3.7e-05 23.8 0.0 0.41 10.7 0.0 3.0 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 OAP56000.1 - 0.00013 21.7 0.0 0.19 11.4 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein TsaE PF02367.17 OAP56000.1 - 0.0002 21.3 0.0 0.24 11.4 0.0 2.7 3 0 0 3 3 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 OAP56000.1 - 0.00023 21.5 0.9 1.1 9.5 0.1 3.2 2 2 1 3 3 3 2 AAA domain AAA_14 PF13173.6 OAP56000.1 - 0.00033 20.7 0.0 1.3 9.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 OAP56000.1 - 0.001 19.6 0.0 1.6 9.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 OAP56000.1 - 0.0012 19.2 0.0 2.7 8.4 0.0 2.5 2 0 0 2 2 2 2 RNA helicase Zeta_toxin PF06414.12 OAP56000.1 - 0.0015 17.9 0.0 0.61 9.3 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin Mg_chelatase PF01078.21 OAP56000.1 - 0.0018 17.7 0.0 0.78 9.1 0.1 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI ABC_tran PF00005.27 OAP56000.1 - 0.0018 18.8 0.0 2.2 8.8 0.0 2.8 2 0 0 2 2 2 1 ABC transporter AAA_7 PF12775.7 OAP56000.1 - 0.0019 17.8 0.0 0.14 11.6 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_33 PF13671.6 OAP56000.1 - 0.0053 16.9 0.0 0.63 10.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 OAP56000.1 - 0.0072 16.2 0.0 0.18 11.7 0.0 2.3 2 0 0 2 2 2 1 NTPase Sigma54_activat PF00158.26 OAP56000.1 - 0.012 15.3 0.0 1.1 9.0 0.0 2.6 2 1 0 2 2 2 0 Sigma-54 interaction domain Vps4_C PF09336.10 OAP56000.1 - 0.014 15.3 0.1 9 6.4 0.0 2.7 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain cobW PF02492.19 OAP56000.1 - 0.019 14.6 0.2 0.26 10.8 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.6 OAP56000.1 - 0.028 14.7 0.0 6.8 6.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 OAP56000.1 - 0.044 14.2 0.0 3.4 8.1 0.0 2.9 3 0 0 3 3 2 0 AAA domain AAA_19 PF13245.6 OAP56000.1 - 0.046 14.1 0.0 0.73 10.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 OAP56000.1 - 0.048 13.4 0.0 1.4 8.7 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation T2SSE PF00437.20 OAP56000.1 - 0.067 12.2 0.7 0.33 10.0 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein ATPase PF06745.13 OAP56000.1 - 0.12 11.7 0.0 13 5.1 0.0 2.3 2 0 0 2 2 2 0 KaiC AAA_25 PF13481.6 OAP56000.1 - 0.15 11.6 3.9 1.4 8.4 0.1 3.5 2 2 2 4 4 4 0 AAA domain APS_kinase PF01583.20 OAP56000.1 - 0.15 11.9 0.1 0.91 9.4 0.0 2.1 2 0 0 2 2 2 0 Adenylylsulphate kinase PEX-2N PF09263.10 OAP56000.1 - 0.19 12.1 0.2 16 5.9 0.0 2.8 2 1 0 2 2 2 0 Peroxisome biogenesis factor 1, N-terminal AAA_24 PF13479.6 OAP56000.1 - 0.19 11.4 0.1 17 5.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 OAP56000.1 - 1.8 8.4 4.8 4.1 7.2 0.1 3.5 4 0 0 4 4 4 0 P-loop containing region of AAA domain MCM PF00493.23 OAP56001.1 - 1.3e-103 344.9 0.0 2e-103 344.3 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 OAP56001.1 - 3.1e-31 107.8 0.3 5.8e-31 107.0 0.3 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_N PF14551.6 OAP56001.1 - 2.8e-21 76.1 1.2 6.4e-21 74.9 1.2 1.7 1 0 0 1 1 1 1 MCM N-terminal domain MCM_lid PF17855.1 OAP56001.1 - 4.4e-20 71.9 0.2 1e-19 70.7 0.2 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 OAP56001.1 - 6.6e-07 28.9 0.0 5.6e-05 22.6 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 OAP56001.1 - 4.8e-06 26.6 0.0 1.4e-05 25.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_lid_2 PF17863.1 OAP56001.1 - 0.025 14.4 0.0 0.077 12.8 0.0 1.8 1 0 0 1 1 1 0 AAA lid domain AAA_3 PF07726.11 OAP56001.1 - 0.033 14.1 0.0 0.12 12.3 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase_C PF13335.6 OAP56001.1 - 0.097 13.3 0.1 0.38 11.4 0.1 2.0 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI C-terminal APG6_N PF17675.1 OAP56001.1 - 0.82 10.2 6.7 1.9 9.0 6.7 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region Cyclase PF04199.13 OAP56002.1 - 3.7e-14 53.1 0.1 5.1e-14 52.7 0.1 1.2 1 0 0 1 1 1 1 Putative cyclase DAP3 PF10236.9 OAP56003.1 - 9e-76 255.0 0.0 1.2e-75 254.5 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.6 OAP56003.1 - 0.089 13.2 0.1 0.49 10.8 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain Ribosomal_S26e PF01283.19 OAP56004.1 - 2e-51 172.9 9.3 2.4e-51 172.7 9.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S26e Fer4_7 PF12838.7 OAP56004.1 - 0.024 15.2 1.3 0.59 10.8 0.4 2.3 2 1 0 2 2 2 0 4Fe-4S dicluster domain DUF1918 PF08940.11 OAP56004.1 - 0.091 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) DUF4668 PF15701.5 OAP56004.1 - 0.096 12.5 0.2 0.16 11.7 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4668) Q_salvage PF10343.9 OAP56004.1 - 0.1 12.2 0.0 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 Potential Queuosine, Q, salvage protein family zf_CopZ PF18423.1 OAP56004.1 - 0.12 12.4 1.8 0.14 12.1 0.0 2.0 3 0 0 3 3 3 0 Zinc binding domain SF1-HH PF16275.5 OAP56004.1 - 0.17 12.2 1.5 0.22 11.8 1.3 1.3 1 1 0 1 1 1 0 Splicing factor 1 helix-hairpin domain Pkinase PF00069.25 OAP56005.1 - 1e-58 198.8 0.0 3.9e-58 196.9 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP56005.1 - 6.5e-28 97.7 0.0 9.5e-28 97.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OAP56005.1 - 0.0011 18.0 0.0 0.0018 17.3 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OAP56005.1 - 0.096 12.6 0.1 0.17 11.7 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family CBF PF03914.17 OAP56005.1 - 0.15 12.1 0.0 0.34 10.9 0.0 1.6 1 0 0 1 1 1 0 CBF/Mak21 family Sugar_tr PF00083.24 OAP56006.1 - 1.2e-93 314.4 15.9 1.6e-93 314.1 15.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP56006.1 - 1.2e-30 106.6 43.7 3.1e-20 72.4 15.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 OAP56006.1 - 0.0035 16.7 8.2 0.0035 16.7 8.2 3.1 2 1 1 3 3 3 2 Uncharacterised MFS-type transporter YbfB CLN3 PF02487.17 OAP56006.1 - 0.033 13.2 11.1 0.075 12.1 6.3 2.1 2 0 0 2 2 2 0 CLN3 protein COesterase PF00135.28 OAP56007.1 - 3.1e-63 214.4 0.1 3.4e-62 211.0 0.1 2.0 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAP56007.1 - 4.1e-05 23.5 0.1 0.0001 22.2 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold CFEM PF05730.11 OAP56008.1 - 6.7e-07 29.3 8.9 6.7e-07 29.3 8.9 1.6 2 0 0 2 2 2 1 CFEM domain CFEM PF05730.11 OAP56010.1 - 9.2e-05 22.5 7.1 0.11 12.6 1.6 2.4 2 0 0 2 2 2 2 CFEM domain p450 PF00067.22 OAP56011.1 - 7.3e-64 216.2 0.0 1.7e-63 215.0 0.0 1.5 2 0 0 2 2 2 1 Cytochrome P450 DTC PF18102.1 OAP56011.1 - 0.16 12.1 0.0 0.52 10.4 0.0 1.7 1 1 1 2 2 2 0 Deltex C-terminal domain Hydrolase PF00702.26 OAP56012.1 - 0.00052 20.4 0.0 0.044 14.1 0.0 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OAP56012.1 - 0.0033 17.5 0.0 0.0067 16.5 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.6 OAP56012.1 - 0.0038 17.4 0.0 0.013 15.6 0.0 1.9 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase 5-nucleotidase PF06189.12 OAP56012.1 - 0.02 13.8 0.0 0.033 13.1 0.0 1.2 1 0 0 1 1 1 0 5'-nucleotidase Methyltransf_31 PF13847.6 OAP56013.1 - 2.4e-11 43.7 0.0 1.6e-10 40.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAP56013.1 - 4.4e-10 40.1 0.0 1.1e-09 38.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAP56013.1 - 2.8e-09 37.0 0.0 4.2e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAP56013.1 - 3.7e-08 33.9 0.0 7.2e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAP56013.1 - 2.3e-07 31.5 0.0 7.1e-07 29.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAP56013.1 - 0.0021 17.4 0.0 0.03 13.7 0.0 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 OAP56013.1 - 0.066 12.7 0.0 0.29 10.6 0.0 2.0 2 0 0 2 2 2 0 Putative methyltransferase CheR PF01739.18 OAP56013.1 - 0.081 12.4 0.0 0.2 11.1 0.0 1.6 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain MTS PF05175.14 OAP56013.1 - 0.12 11.9 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Amidase PF01425.21 OAP56014.1 - 9.1e-86 288.6 0.2 1.4e-85 288.0 0.2 1.2 1 0 0 1 1 1 1 Amidase Aa_trans PF01490.18 OAP56015.1 - 6.2e-24 84.5 33.0 7.2e-24 84.2 33.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Fungal_trans_2 PF11951.8 OAP56016.1 - 8.5e-18 64.3 3.2 1.2e-17 63.8 3.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP56016.1 - 1.1e-06 28.6 5.3 2.3e-06 27.6 5.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FadA PF09403.10 OAP56016.1 - 0.027 14.9 0.2 0.061 13.8 0.2 1.5 1 0 0 1 1 1 0 Adhesion protein FadA MIT PF04212.18 OAP56016.1 - 0.12 12.4 1.2 0.57 10.3 0.0 2.4 2 1 0 2 2 2 0 MIT (microtubule interacting and transport) domain UAF_Rrn10 PF05234.11 OAP56017.1 - 0.00097 19.4 0.0 0.0015 18.7 0.0 1.3 1 0 0 1 1 1 1 UAF complex subunit Rrn10 Arrestin_N PF00339.29 OAP56018.1 - 2e-10 40.9 0.0 6.7e-10 39.2 0.0 1.9 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 OAP56018.1 - 5.6e-08 33.3 0.5 2.9e-07 31.0 0.0 2.5 3 1 0 3 3 3 1 Arrestin (or S-antigen), C-terminal domain Pkinase PF00069.25 OAP56019.1 - 2.4e-09 36.9 0.0 3.6e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain WaaY PF06176.11 OAP56019.1 - 5.2e-05 23.0 0.0 0.00011 21.8 0.0 1.5 2 0 0 2 2 2 1 Lipopolysaccharide core biosynthesis protein (WaaY) Pkinase_Tyr PF07714.17 OAP56019.1 - 0.00074 18.9 0.0 0.0011 18.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OAP56019.1 - 0.0016 17.8 0.0 0.0027 17.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OAP56019.1 - 0.13 11.9 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 RIO1 family AA_permease PF00324.21 OAP56021.1 - 1.6e-143 478.8 34.8 1.8e-143 478.6 34.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAP56021.1 - 8.4e-42 143.5 36.6 1.1e-41 143.0 36.6 1.1 1 0 0 1 1 1 1 Amino acid permease PMM PF03332.13 OAP56022.1 - 1.8e-96 322.1 0.0 2.2e-96 321.9 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 OAP56022.1 - 0.0012 18.6 0.0 0.93 9.2 0.0 2.1 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Trehalose_PPase PF02358.16 OAP56022.1 - 0.05 12.7 0.0 0.096 11.8 0.0 1.4 2 0 0 2 2 2 0 Trehalose-phosphatase MFS_1 PF07690.16 OAP56023.1 - 7.2e-20 71.2 38.0 7.2e-20 71.2 38.0 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Fungal_trans PF04082.18 OAP56024.1 - 2.5e-08 33.3 0.1 4.3e-08 32.5 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP56024.1 - 1.3e-06 28.4 13.5 2.7e-06 27.4 13.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amidohydro_2 PF04909.14 OAP56025.1 - 9.7e-39 133.9 1.6 1.2e-38 133.5 1.6 1.1 1 0 0 1 1 1 1 Amidohydrolase N6-adenineMlase PF10237.9 OAP56025.1 - 0.15 11.8 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 Probable N6-adenine methyltransferase FAD_binding_3 PF01494.19 OAP56026.1 - 6.7e-19 68.3 0.0 1.4e-18 67.3 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 OAP56026.1 - 1.6e-08 34.6 1.2 4.9e-08 33.1 1.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAP56026.1 - 5.5e-07 29.1 0.9 1.1e-06 28.1 0.9 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OAP56026.1 - 8.2e-07 28.4 0.5 1.5e-06 27.6 0.5 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 OAP56026.1 - 5.7e-06 25.7 4.5 1e-05 24.9 4.4 1.5 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAP56026.1 - 7.2e-06 25.8 7.9 7.9e-05 22.4 5.8 2.2 1 1 1 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 OAP56026.1 - 1.3e-05 24.8 0.0 1.7e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 OAP56026.1 - 0.00015 21.2 0.3 0.016 14.6 0.2 2.3 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 OAP56026.1 - 0.0006 20.3 0.2 0.002 18.6 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAP56026.1 - 0.00075 18.3 1.4 0.0011 17.8 1.4 1.2 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.22 OAP56026.1 - 0.0013 18.0 2.2 0.0013 18.0 2.2 1.6 2 0 0 2 2 2 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 OAP56026.1 - 0.0013 18.1 0.6 0.0021 17.4 0.6 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_Gly3P_dh_N PF01210.23 OAP56026.1 - 0.14 12.1 0.2 0.22 11.5 0.2 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox_3 PF13738.6 OAP56026.1 - 0.19 10.9 0.5 0.4 9.9 0.5 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 OAP56026.1 - 0.27 11.1 1.1 0.53 10.2 1.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SSF PF00474.17 OAP56027.1 - 2.5e-15 56.3 22.0 4.8e-15 55.3 22.0 1.4 1 0 0 1 1 1 1 Sodium:solute symporter family Amidase PF01425.21 OAP56028.1 - 2e-97 327.0 0.0 2.6e-97 326.6 0.0 1.2 1 0 0 1 1 1 1 Amidase DUF807 PF05660.11 OAP56028.1 - 0.15 12.0 0.0 0.33 10.9 0.0 1.5 1 0 0 1 1 1 0 Coxiella burnetii protein of unknown function (DUF807) Fungal_trans_2 PF11951.8 OAP56029.1 - 8.9e-35 120.2 0.9 1.1e-34 119.9 0.9 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 OAP56030.1 - 1.3e-41 142.7 52.0 1.3e-40 139.4 52.0 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 OAP56030.1 - 4.1e-09 35.4 21.3 1.9e-08 33.2 20.6 2.1 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) p450 PF00067.22 OAP56031.1 - 6.7e-72 242.7 0.0 8.4e-72 242.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ERAP1_C PF11838.8 OAP56032.1 - 5.7e-89 298.8 0.5 1.3e-88 297.6 0.1 1.8 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 OAP56032.1 - 3.7e-86 288.2 0.5 6.2e-86 287.5 0.5 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 OAP56032.1 - 2.4e-47 161.5 1.4 2.5e-47 161.5 0.3 1.6 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain DUF3543 PF12063.8 OAP56033.1 - 1.4e-93 312.9 0.1 2.2e-93 312.2 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase PF00069.25 OAP56033.1 - 5.8e-62 209.4 0.0 1e-61 208.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP56033.1 - 2.9e-43 148.0 0.0 5.3e-43 147.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase DUF4630 PF15443.6 OAP56033.1 - 0.056 13.6 0.8 0.12 12.5 0.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4630) Kinase-like PF14531.6 OAP56033.1 - 0.061 12.6 0.0 1.9 7.8 0.0 2.3 2 0 0 2 2 2 0 Kinase-like APH PF01636.23 OAP56033.1 - 0.079 12.9 0.0 0.2 11.6 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family Taxilin PF09728.9 OAP56035.1 - 4.5e-83 279.0 59.4 4.5e-83 279.0 59.4 1.8 1 1 1 2 2 2 1 Myosin-like coiled-coil protein CENP-B_dimeris PF09026.10 OAP56035.1 - 0.25 11.7 12.3 0.73 10.2 8.5 2.8 2 0 0 2 2 2 0 Centromere protein B dimerisation domain M16C_assoc PF08367.11 OAP56036.1 - 6.1e-68 228.7 0.1 1.1e-67 227.8 0.1 1.5 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 OAP56036.1 - 4.2e-20 72.5 0.0 3e-13 50.2 0.0 3.3 4 0 0 4 4 4 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 OAP56036.1 - 2e-05 24.6 0.3 7.8e-05 22.7 0.0 2.2 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) CDC14 PF08045.11 OAP56037.1 - 0.015 14.5 0.0 0.031 13.4 0.0 1.5 1 1 0 1 1 1 0 Cell division control protein 14, SIN component Amidohydro_2 PF04909.14 OAP56038.1 - 0.0001 22.2 0.0 0.00022 21.1 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.20 OAP56038.1 - 0.00053 19.4 0.0 0.00095 18.6 0.0 1.5 1 1 0 1 1 1 1 Amidohydrolase family CoA_binding_2 PF13380.6 OAP56038.1 - 0.0027 18.2 0.0 0.0059 17.1 0.0 1.5 1 0 0 1 1 1 1 CoA binding domain FMO-like PF00743.19 OAP56039.1 - 7.9e-14 51.0 0.1 3.2e-13 49.0 0.0 2.0 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 OAP56039.1 - 5.2e-11 42.3 0.0 1.1e-08 34.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAP56039.1 - 2.7e-10 40.0 0.0 6.3e-10 38.8 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAP56039.1 - 9.1e-06 25.0 0.1 7.8e-05 22.0 0.0 2.2 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 OAP56039.1 - 4.9e-05 23.5 0.0 0.0034 17.6 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 OAP56039.1 - 0.00038 21.0 0.4 0.15 12.7 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAP56039.1 - 0.002 18.1 0.3 5.2 7.0 0.1 4.5 4 1 1 5 5 5 1 FAD-NAD(P)-binding 2-Hacid_dh_C PF02826.19 OAP56039.1 - 0.064 12.6 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain APH PF01636.23 OAP56040.1 - 0.00075 19.5 0.1 0.0014 18.6 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Meth_synt_2 PF01717.18 OAP56041.1 - 9.9e-11 41.5 0.0 2.4e-09 36.9 0.0 2.6 2 1 0 2 2 2 1 Cobalamin-independent synthase, Catalytic domain MDM31_MDM32 PF08118.11 OAP56042.1 - 3.3e-239 794.9 0.0 3.9e-239 794.7 0.0 1.0 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins Kelch_2 PF07646.15 OAP56043.1 - 8.9e-05 22.3 6.0 0.096 12.7 0.1 4.4 4 0 0 4 4 4 2 Kelch motif Kelch_5 PF13854.6 OAP56043.1 - 0.0009 19.2 3.8 0.019 15.0 0.6 3.1 2 0 0 2 2 2 1 Kelch motif Kelch_4 PF13418.6 OAP56043.1 - 0.0037 17.2 6.7 2.2 8.3 0.5 4.2 3 1 0 3 3 3 2 Galactose oxidase, central domain Kelch_3 PF13415.6 OAP56043.1 - 0.032 14.5 12.7 0.061 13.6 1.2 4.1 2 1 1 3 3 3 0 Galactose oxidase, central domain Yip1 PF04893.17 OAP56043.1 - 0.077 12.7 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Yip1 domain Kelch_6 PF13964.6 OAP56043.1 - 0.099 13.0 11.9 0.87 10.0 0.1 4.8 3 1 2 5 5 5 0 Kelch motif Kelch_1 PF01344.25 OAP56043.1 - 5.7 6.6 8.6 14 5.4 0.1 4.1 4 0 0 4 4 4 0 Kelch motif KH_8 PF17903.1 OAP56044.1 - 4.6e-05 23.4 0.0 0.00013 21.9 0.0 1.7 2 0 0 2 2 2 1 Krr1 KH1 domain KH_1 PF00013.29 OAP56044.1 - 0.034 14.0 0.7 0.078 12.8 0.7 1.6 1 0 0 1 1 1 0 KH domain Proteasome PF00227.26 OAP56045.1 - 7.6e-32 110.3 0.1 1.6e-31 109.3 0.1 1.6 1 1 0 1 1 1 1 Proteasome subunit DNA_pol_phi PF04931.13 OAP56048.1 - 0.23 9.5 27.1 0.3 9.2 27.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 OAP56048.1 - 0.31 9.3 25.3 0.4 8.9 25.3 1.1 1 0 0 1 1 1 0 CDC45-like protein IFT57 PF10498.9 OAP56048.1 - 0.4 9.6 13.7 0.53 9.2 13.7 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 SAPS PF04499.15 OAP56048.1 - 0.84 8.3 9.4 0.87 8.3 9.4 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein BSP_II PF05432.11 OAP56048.1 - 0.85 9.3 23.5 1.4 8.6 23.5 1.4 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Hid1 PF12722.7 OAP56048.1 - 1.7 6.7 11.2 1.7 6.7 11.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Presenilin PF01080.17 OAP56048.1 - 4.6 5.9 12.4 5.5 5.6 12.4 1.3 1 0 0 1 1 1 0 Presenilin eIF-3c_N PF05470.12 OAP56048.1 - 5 5.3 14.8 6.1 5.0 14.8 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus FAM76 PF16046.5 OAP56048.1 - 6 6.1 10.1 6 6.1 9.5 1.3 1 1 0 1 1 1 0 FAM76 protein Zip PF02535.22 OAP56048.1 - 10 5.3 8.9 13 4.9 8.9 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter RGS PF00615.19 OAP56049.1 - 0.032 14.5 0.0 0.096 13.0 0.0 1.8 2 0 0 2 2 2 0 Regulator of G protein signaling domain Epimerase PF01370.21 OAP56050.1 - 1.4e-05 24.7 0.0 0.0013 18.2 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 OAP56050.1 - 3e-05 24.0 0.0 4.6e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 OAP56050.1 - 0.00021 20.9 0.0 0.00034 20.3 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.24 OAP56050.1 - 0.033 14.6 0.0 0.19 12.2 0.0 2.2 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 OAP56050.1 - 0.084 13.1 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DUF1521 PF07481.11 OAP56050.1 - 0.12 12.4 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1521) FRG2 PF15315.6 OAP56052.1 - 0.018 15.3 9.4 0.084 13.1 6.8 1.9 1 1 1 2 2 2 0 Facioscapulohumeral muscular dystrophy candidate 2 NHase_beta PF02211.15 OAP56052.1 - 0.058 13.4 4.5 0.065 13.2 4.5 1.1 1 0 0 1 1 1 0 Nitrile hydratase beta subunit Mucin PF01456.17 OAP56052.1 - 2.5 8.1 19.3 2.6 8.1 18.8 1.3 1 1 0 1 1 1 0 Mucin-like glycoprotein Exo_endo_phos PF03372.23 OAP56053.1 - 3.8e-11 42.9 0.0 8.2e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF5345 PF17280.2 OAP56053.1 - 0.12 12.3 0.1 0.26 11.3 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5345) Pinin_SDK_memA PF04696.13 OAP56054.1 - 4.5e-31 107.6 14.4 4.5e-31 107.6 14.4 3.6 3 1 1 4 4 4 2 pinin/SDK/memA/ protein conserved region PHF5 PF03660.14 OAP56055.1 - 1.3e-52 176.3 9.5 1.5e-52 176.2 9.5 1.0 1 0 0 1 1 1 1 PHF5-like protein PolC_DP2 PF03833.13 OAP56055.1 - 0.34 8.7 6.5 0.36 8.6 6.5 1.2 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DZR PF12773.7 OAP56055.1 - 1.3 9.1 14.6 2.3 8.3 1.3 3.0 1 1 1 2 2 2 0 Double zinc ribbon Cofilin_ADF PF00241.20 OAP56056.1 - 7.4e-23 80.6 0.0 3.8e-12 46.1 0.0 2.2 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein p450 PF00067.22 OAP56057.1 - 5.2e-60 203.5 0.0 6.8e-60 203.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.18 OAP56058.1 - 5.5e-07 29.6 8.3 1.2e-06 28.6 8.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1338 PF07063.13 OAP56058.1 - 0.11 11.7 1.1 0.14 11.3 0.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1338) Clr5 PF14420.6 OAP56059.1 - 2.9e-08 33.8 0.8 7e-08 32.6 0.8 1.7 1 0 0 1 1 1 1 Clr5 domain Ank_2 PF12796.7 OAP56059.1 - 1e-05 26.0 0.0 0.29 11.7 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OAP56059.1 - 1.2e-05 25.4 0.1 0.15 12.4 0.0 4.2 4 1 1 5 5 5 2 Ankyrin repeats (many copies) DUF2680 PF10925.8 OAP56059.1 - 0.16 12.0 0.3 0.35 10.9 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2680) OrfB_IS605 PF01385.19 OAP56059.1 - 0.23 11.7 0.7 2.2 8.5 0.7 2.3 1 1 0 1 1 1 0 Probable transposase DUF917 PF06032.12 OAP56060.1 - 1.1e-128 429.0 0.3 3.3e-126 420.8 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF917) Hydant_A_N PF05378.13 OAP56060.1 - 2.4e-29 102.3 0.2 1.6e-26 93.1 0.0 2.6 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region Hydantoinase_A PF01968.18 OAP56060.1 - 7.7e-27 94.3 2.8 2e-23 83.1 0.8 3.3 2 1 0 3 3 3 2 Hydantoinase/oxoprolinase Fungal_trans PF04082.18 OAP56060.1 - 2.1e-14 53.2 0.2 4.6e-14 52.1 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP56060.1 - 6.7e-06 26.1 7.4 1.5e-05 25.0 7.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BcrAD_BadFG PF01869.20 OAP56060.1 - 0.00013 21.6 0.3 0.0023 17.5 0.1 2.5 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family MutL PF13941.6 OAP56060.1 - 0.00035 19.3 3.7 0.0055 15.4 0.1 2.7 3 0 0 3 3 3 2 MutL protein FtsA PF14450.6 OAP56060.1 - 0.0034 17.8 0.5 1 9.8 0.0 3.0 2 0 0 2 2 2 1 Cell division protein FtsA ROK PF00480.20 OAP56060.1 - 0.14 11.6 0.0 0.31 10.5 0.0 1.5 1 0 0 1 1 1 0 ROK family StbA PF06406.11 OAP56060.1 - 0.19 10.9 0.4 16 4.6 0.2 2.3 2 0 0 2 2 2 0 StbA protein Transp_cyt_pur PF02133.15 OAP56061.1 - 2e-97 326.8 29.1 2.2e-97 326.6 29.1 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin MFS_1 PF07690.16 OAP56062.1 - 8.5e-22 77.5 27.3 8.5e-22 77.5 27.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Mito_carr PF00153.27 OAP56064.1 - 1.1e-68 227.2 1.5 2.2e-22 78.8 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Annexin PF00191.20 OAP56066.1 - 9.5e-62 205.0 2.0 2.1e-18 66.1 0.0 4.2 4 0 0 4 4 4 4 Annexin Acetyltransf_11 PF13720.6 OAP56066.1 - 0.049 14.1 2.5 2.4 8.7 0.0 3.6 4 0 0 4 4 4 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 AA_permease_2 PF13520.6 OAP56068.1 - 2.9e-82 276.8 40.4 3.8e-82 276.4 40.4 1.2 1 0 0 1 1 1 1 Amino acid permease Abhydrolase_1 PF00561.20 OAP56069.1 - 3.9e-29 102.1 0.6 4e-28 98.8 0.6 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAP56069.1 - 1.8e-19 71.2 0.4 2.5e-19 70.7 0.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAP56069.1 - 2.4e-11 43.4 0.0 3.6e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 baeRF_family10 PF18854.1 OAP56069.1 - 0.049 13.9 0.1 0.16 12.3 0.0 1.8 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 10 Glyco_hydro_31 PF01055.26 OAP56070.1 - 1.5e-97 327.6 5.3 2.2e-97 327.0 5.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 DUF4968 PF16338.5 OAP56070.1 - 0.028 14.7 0.0 0.071 13.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4968) PP2C PF00481.21 OAP56071.1 - 3.1e-52 177.7 0.0 5.2e-52 177.0 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_8 PF13855.6 OAP56071.1 - 2.6e-40 136.0 59.0 1.1e-10 41.1 2.1 10.8 6 2 7 13 13 13 11 Leucine rich repeat LRR_4 PF12799.7 OAP56071.1 - 1.2e-33 114.6 70.0 0.00027 21.3 0.4 12.2 11 1 3 14 14 14 11 Leucine Rich repeats (2 copies) Guanylate_cyc PF00211.20 OAP56071.1 - 4.2e-26 91.7 0.0 5.7e-25 88.0 0.0 2.3 1 1 1 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain LRR_9 PF14580.6 OAP56071.1 - 3e-07 30.1 24.1 0.02 14.4 0.5 5.9 2 2 3 6 6 6 5 Leucine-rich repeat Ad_cyc_g-alpha PF08509.11 OAP56071.1 - 6.1e-06 25.9 0.0 2.2e-05 24.0 0.0 2.0 1 0 0 1 1 1 1 Adenylate cyclase G-alpha binding domain RA PF00788.23 OAP56071.1 - 5e-05 23.9 0.0 0.00016 22.2 0.0 1.8 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain LRR_1 PF00560.33 OAP56071.1 - 0.00016 21.8 58.2 9 7.3 0.2 16.2 17 1 0 17 17 17 2 Leucine Rich Repeat LRR_5 PF13306.6 OAP56071.1 - 0.0092 15.9 14.4 0.29 11.1 0.2 4.9 5 1 1 6 6 6 2 BspA type Leucine rich repeat region (6 copies) DUF4665 PF15679.5 OAP56071.1 - 0.11 13.1 0.0 0.75 10.5 0.0 2.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4665) ATP-synt_G PF04718.15 OAP56072.1 - 1.3e-32 112.6 0.1 3.7e-32 111.1 0.0 1.7 2 0 0 2 2 2 1 Mitochondrial ATP synthase g subunit Caskin-Pro-rich PF16907.5 OAP56074.1 - 1.2 9.7 8.2 0.18 12.3 2.6 2.3 3 0 0 3 3 3 0 Proline rich region of Caskin proteins Helicase_C PF00271.31 OAP56075.1 - 1.2e-26 93.2 0.0 3.5e-26 91.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 OAP56075.1 - 2.1e-25 89.5 0.0 5.7e-25 88.1 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 OAP56075.1 - 0.00012 22.1 0.3 0.00033 20.7 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SPAN-X PF07458.12 OAP56075.1 - 0.4 11.1 3.9 1 9.9 3.9 1.7 1 0 0 1 1 1 0 Sperm protein associated with nucleus, mapped to X chromosome Bac_rhamnosid6H PF17389.2 OAP56076.1 - 7e-105 351.0 0.2 9.2e-105 350.6 0.2 1.1 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_N PF08531.10 OAP56076.1 - 2.7e-42 144.5 0.1 5.5e-42 143.5 0.1 1.5 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain Bac_rhamnosid PF05592.11 OAP56076.1 - 1.7e-26 92.1 0.0 3.2e-26 91.3 0.0 1.5 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase concanavalin-like domain Bac_rhamnosid_C PF17390.2 OAP56076.1 - 1.9e-18 66.0 0.0 5.7e-18 64.5 0.0 1.8 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain Clr2_transil PF16761.5 OAP56078.1 - 2.6e-13 50.6 0.1 6.3e-13 49.4 0.1 1.7 1 0 0 1 1 1 1 Transcription-silencing protein, cryptic loci regulator Clr2 Clr2 PF10383.9 OAP56078.1 - 0.0012 19.7 0.0 0.004 18.0 0.0 1.9 1 0 0 1 1 1 1 Transcription-silencing protein Clr2 NOA36 PF06524.12 OAP56078.1 - 2.8 7.2 9.7 5.1 6.3 9.7 1.3 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.14 OAP56078.1 - 9.7 4.3 10.4 15 3.7 10.4 1.2 1 0 0 1 1 1 0 CDC45-like protein Ribosomal_L22 PF00237.19 OAP56079.1 - 8.4e-42 141.6 0.8 8.6e-42 141.6 0.1 1.4 2 0 0 2 2 2 1 Ribosomal protein L22p/L17e MFS_1 PF07690.16 OAP56080.1 - 2.3e-37 128.8 54.9 4.8e-32 111.3 36.4 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Cu_bind_like PF02298.17 OAP56081.1 - 0.03 14.3 0.1 0.07 13.1 0.1 1.6 1 1 0 1 1 1 0 Plastocyanin-like domain Apt1 PF10351.9 OAP56081.1 - 0.65 8.8 3.9 0.69 8.7 3.9 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Spc7 PF08317.11 OAP56082.1 - 0.0097 14.8 3.9 0.018 14.0 3.9 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein Fib_alpha PF08702.10 OAP56082.1 - 0.13 12.5 4.3 0.36 11.0 4.3 1.7 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family TMF_TATA_bd PF12325.8 OAP56082.1 - 0.57 10.4 8.2 0.39 10.9 6.2 1.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Abhydrolase_3 PF07859.13 OAP56083.1 - 3.5e-29 102.2 0.0 5e-29 101.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 OAP56083.1 - 4.4e-16 58.7 0.0 5.8e-16 58.3 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_2 PF02230.16 OAP56083.1 - 0.069 12.9 0.0 0.18 11.5 0.0 1.7 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase DUF2227 PF09988.9 OAP56083.1 - 0.097 12.5 0.3 0.31 10.9 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized metal-binding protein (DUF2227) RRM_1 PF00076.22 OAP56084.1 - 2.3e-43 145.9 0.3 2.5e-20 72.0 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 OAP56084.1 - 2.7e-23 82.9 0.5 8.7e-23 81.2 0.2 2.1 2 0 0 2 2 2 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_occluded PF16842.5 OAP56084.1 - 0.00012 21.8 0.0 0.17 11.7 0.0 2.5 2 0 0 2 2 2 2 Occluded RNA-recognition motif RRM_3 PF08777.11 OAP56084.1 - 0.015 15.4 0.0 0.082 13.0 0.0 2.2 2 0 0 2 2 2 0 RNA binding motif PHM7_cyt PF14703.6 OAP56084.1 - 0.015 15.5 0.1 1.2 9.4 0.1 2.7 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter RRM_7 PF16367.5 OAP56084.1 - 0.043 13.9 0.0 1.2 9.3 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif RRM_5 PF13893.6 OAP56084.1 - 0.15 11.7 0.0 0.45 10.1 0.0 1.8 1 1 1 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3433 PF11915.8 OAP56086.1 - 9.4e-11 42.0 6.8 9.4e-11 42.0 6.8 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3433) DUF202 PF02656.15 OAP56088.1 - 4.2e-13 49.5 0.1 4.2e-13 49.5 0.1 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF202) TMEM100 PF16311.5 OAP56088.1 - 0.0033 17.0 0.3 0.0049 16.4 0.3 1.3 1 0 0 1 1 1 1 Transmembrane protein 100 Ribosomal_S8 PF00410.19 OAP56089.1 - 1.5e-21 76.6 0.3 2.3e-21 76.1 0.3 1.3 1 1 0 1 1 1 1 Ribosomal protein S8 Ribosomal_S25 PF03297.15 OAP56090.1 - 8.8e-39 131.8 3.3 9.7e-39 131.7 3.3 1.0 1 0 0 1 1 1 1 S25 ribosomal protein MarR_2 PF12802.7 OAP56090.1 - 0.007 16.2 0.1 0.0088 15.9 0.1 1.3 1 0 0 1 1 1 1 MarR family HTH_24 PF13412.6 OAP56090.1 - 0.036 13.6 0.1 0.056 13.0 0.1 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Cas_Csm6 PF09659.10 OAP56090.1 - 0.12 11.1 0.1 0.14 10.9 0.1 1.0 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csm6) Cyt-b5 PF00173.28 OAP56091.1 - 8.9e-13 48.2 0.0 1.3e-12 47.6 0.0 1.4 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain AAA_14 PF13173.6 OAP56091.1 - 0.14 12.2 0.1 0.22 11.6 0.1 1.2 1 0 0 1 1 1 0 AAA domain Pro-rich PF15240.6 OAP56092.1 - 0.047 14.0 39.5 0.11 12.8 39.5 1.5 1 0 0 1 1 1 0 Proline-rich NMT1 PF09084.11 OAP56094.1 - 6.7e-05 22.9 0.0 0.0047 16.9 0.0 2.5 2 1 0 2 2 2 2 NMT1/THI5 like Phosphonate-bd PF12974.7 OAP56094.1 - 0.041 13.5 0.0 0.048 13.2 0.0 1.2 1 0 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein Fungal_trans PF04082.18 OAP56095.1 - 1.1e-39 136.2 0.5 1.8e-39 135.4 0.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 OAP56095.1 - 1.9e-37 129.0 33.6 3.3e-37 128.2 33.6 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAP56095.1 - 1.1e-12 47.6 7.0 1.1e-12 47.6 7.0 2.4 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 OAP56095.1 - 4.3e-05 22.1 5.4 6.7e-05 21.5 5.4 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.6 OAP56095.1 - 0.32 9.5 21.6 0.031 12.8 11.2 3.0 2 2 0 2 2 2 0 MFS/sugar transport protein p450 PF00067.22 OAP56096.1 - 9.4e-77 258.7 0.0 1.3e-76 258.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Amido_AtzD_TrzD PF09663.10 OAP56097.1 - 5.8e-115 384.2 4.7 7e-115 383.9 4.7 1.1 1 0 0 1 1 1 1 Amidohydrolase ring-opening protein (Amido_AtzD_TrzD) GST_N_3 PF13417.6 OAP56098.1 - 9.5e-17 61.2 0.0 1.7e-16 60.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 OAP56098.1 - 8.1e-15 54.9 0.0 1.5e-14 54.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OAP56098.1 - 2.6e-11 43.7 0.0 6.1e-11 42.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OAP56098.1 - 1.3e-10 41.3 0.0 2.4e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OAP56098.1 - 8.9e-10 38.7 0.0 1.6e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OAP56098.1 - 2.9e-07 30.4 0.0 5e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 OAP56098.1 - 0.001 19.6 0.0 0.36 11.4 0.0 2.3 2 0 0 2 2 2 2 Glutathione S-transferase, C-terminal domain DUF3791 PF12668.7 OAP56098.1 - 0.037 14.1 0.0 0.073 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3791) Zn_clus PF00172.18 OAP56099.1 - 9.2e-08 32.1 7.7 1.6e-07 31.3 7.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Opy2 PF09463.10 OAP56099.1 - 0.53 10.6 8.0 0.064 13.6 2.1 2.2 2 0 0 2 2 2 0 Opy2 protein Amidohydro_2 PF04909.14 OAP56100.1 - 1.8e-06 27.9 0.0 2e-06 27.8 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase Bac_luciferase PF00296.20 OAP56101.1 - 1e-52 179.5 0.0 1.8e-52 178.8 0.0 1.3 1 1 0 1 1 1 1 Luciferase-like monooxygenase MFS_1 PF07690.16 OAP56102.1 - 7.6e-18 64.5 36.5 7.6e-18 64.5 36.5 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily AA_permease PF00324.21 OAP56103.1 - 9.8e-103 344.3 38.4 1.1e-102 344.1 38.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAP56103.1 - 4.8e-28 98.1 42.0 5.8e-28 97.9 42.0 1.1 1 0 0 1 1 1 1 Amino acid permease WTF PF03303.13 OAP56103.1 - 1.1 8.9 9.7 0.76 9.5 6.6 2.2 2 0 0 2 2 2 0 WTF protein Spt20 PF12090.8 OAP56104.1 - 4.2e-43 147.6 0.0 4.2e-43 147.6 0.0 7.9 3 2 1 4 4 4 1 Spt20 family Cdd1 PF11731.8 OAP56104.1 - 0.23 11.7 3.6 0.72 10.1 3.6 1.9 1 0 0 1 1 1 0 Pathogenicity locus Cation_efflux PF01545.21 OAP56106.1 - 3.9e-16 59.4 6.7 4.9e-16 59.0 6.7 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 OAP56106.1 - 4.1e-11 42.8 1.7 9.4e-11 41.7 1.7 1.5 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Bunya_NS-S PF01104.17 OAP56106.1 - 0.045 13.6 1.0 2.5 8.0 0.4 2.6 2 0 0 2 2 2 0 Bunyavirus non-structural protein NS-s GPDPase_memb PF10110.9 OAP56106.1 - 0.11 11.3 0.0 0.11 11.3 0.0 1.9 2 1 0 2 2 2 0 Membrane domain of glycerophosphoryl diester phosphodiesterase zinc_ribbon_15 PF17032.5 OAP56107.1 - 5.2e-06 27.1 0.1 6.9e-06 26.7 0.1 1.2 1 0 0 1 1 1 1 zinc-ribbon family RecR PF02132.15 OAP56107.1 - 1.3 8.7 3.7 12 5.6 3.7 2.0 1 1 0 1 1 1 0 RecR protein FAD_binding_3 PF01494.19 OAP56108.1 - 9.4e-18 64.6 0.2 2.1e-17 63.4 0.2 1.5 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 OAP56108.1 - 1.6e-07 30.9 0.4 6.8e-05 22.2 0.2 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAP56108.1 - 9.7e-07 28.9 0.8 2.5e-06 27.6 0.8 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 OAP56108.1 - 5.1e-06 26.0 1.9 0.051 12.8 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase DAO PF01266.24 OAP56108.1 - 8.9e-06 25.5 6.0 0.046 13.3 4.7 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_oxidored PF12831.7 OAP56108.1 - 1.3e-05 24.8 0.3 2e-05 24.2 0.3 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 OAP56108.1 - 5e-05 23.8 1.0 0.00042 20.8 0.4 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 OAP56108.1 - 6.9e-05 21.9 2.7 0.054 12.3 2.7 3.0 3 0 0 3 3 3 1 Tryptophan halogenase FAD_binding_2 PF00890.24 OAP56108.1 - 0.00063 18.9 7.3 0.0025 16.9 6.9 1.9 2 0 0 2 2 2 1 FAD binding domain SE PF08491.10 OAP56108.1 - 0.019 14.0 0.1 0.042 12.9 0.1 1.5 1 1 0 1 1 1 0 Squalene epoxidase Thi4 PF01946.17 OAP56108.1 - 0.059 12.6 1.0 0.14 11.4 0.5 1.8 2 0 0 2 2 2 0 Thi4 family GIDA PF01134.22 OAP56108.1 - 0.11 11.6 3.2 0.18 10.9 3.2 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 OAP56108.1 - 0.11 11.8 1.6 0.24 10.7 1.6 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 OAP56108.1 - 0.23 10.1 6.1 0.12 11.0 4.2 1.4 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_3 PF13738.6 OAP56108.1 - 0.25 10.5 4.5 0.48 9.6 3.5 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Fibrillarin PF01269.17 OAP56110.1 - 3e-103 343.8 0.0 3.6e-103 343.5 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 OAP56110.1 - 4.6e-06 26.5 0.0 7.5e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltr_RsmB-F PF01189.17 OAP56110.1 - 0.025 14.2 0.0 0.08 12.6 0.0 1.7 2 0 0 2 2 2 0 16S rRNA methyltransferase RsmB/F PCMT PF01135.19 OAP56110.1 - 0.1 12.4 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) LRR_4 PF12799.7 OAP56111.1 - 2e-35 120.2 35.4 5e-09 36.3 2.3 6.8 4 2 0 6 6 6 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OAP56111.1 - 2.3e-28 97.7 34.7 1.1e-11 44.4 4.6 5.7 2 2 2 5 5 5 5 Leucine rich repeat LRR_9 PF14580.6 OAP56111.1 - 1.1e-13 51.1 16.8 3.3e-06 26.7 1.9 3.6 1 1 3 4 4 4 4 Leucine-rich repeat LRR_1 PF00560.33 OAP56111.1 - 1.3e-05 25.1 28.6 1 10.2 0.0 9.3 10 1 0 10 10 10 2 Leucine Rich Repeat LRR_6 PF13516.6 OAP56111.1 - 8.6e-05 22.3 30.1 0.43 10.7 0.7 8.2 11 0 0 11 11 11 4 Leucine Rich repeat UB2H PF14814.6 OAP56111.1 - 0.12 12.4 1.6 18 5.4 0.0 3.9 2 1 2 4 4 4 0 Bifunctional transglycosylase second domain LRR_5 PF13306.6 OAP56111.1 - 0.2 11.6 5.4 0.83 9.6 0.6 2.7 1 1 2 3 3 3 0 BspA type Leucine rich repeat region (6 copies) TBD PF12845.7 OAP56111.1 - 6.1 6.8 6.2 18 5.3 0.3 3.3 3 1 1 4 4 4 0 TBD domain Sec61_beta PF03911.16 OAP56112.1 - 1.4e-17 63.4 0.6 2.1e-17 62.8 0.6 1.3 1 0 0 1 1 1 1 Sec61beta family RraA-like PF03737.15 OAP56113.1 - 2.3e-34 118.7 0.1 2.8e-34 118.5 0.1 1.1 1 0 0 1 1 1 1 Aldolase/RraA Ldh_2 PF02615.14 OAP56114.1 - 5.9e-122 407.0 0.2 6.6e-122 406.8 0.2 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase Sugar_tr PF00083.24 OAP56115.1 - 4.1e-73 246.8 20.4 5.1e-73 246.5 20.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP56115.1 - 3.8e-16 59.0 23.7 3.8e-16 59.0 23.7 2.2 1 1 0 2 2 2 1 Major Facilitator Superfamily Dabb PF07876.12 OAP56116.1 - 2.2e-11 44.2 0.1 3.5e-11 43.6 0.1 1.3 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain T4BSS_DotI_IcmL PF11393.8 OAP56116.1 - 0.12 11.8 0.0 0.17 11.4 0.0 1.1 1 0 0 1 1 1 0 Type-IV b secretion system, inner-membrane complex component Dak1 PF02733.17 OAP56117.1 - 1e-111 372.8 0.0 1.4e-111 372.3 0.0 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 OAP56117.1 - 2.7e-43 147.9 2.2 4.2e-43 147.2 0.9 2.0 2 0 0 2 2 2 1 DAK2 domain F_bP_aldolase PF01116.20 OAP56118.1 - 2.7e-88 296.1 0.0 3e-88 296.0 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Adenyl_cycl_N PF12633.7 OAP56118.1 - 0.048 13.6 0.0 3.8 7.4 0.0 2.1 2 0 0 2 2 2 0 Adenylate cyclase NT domain Amidohydro_2 PF04909.14 OAP56120.1 - 1.1e-22 81.2 0.3 2.5e-22 80.0 0.3 1.5 1 1 0 1 1 1 1 Amidohydrolase Cupin_2 PF07883.11 OAP56121.1 - 2.2e-11 43.3 0.0 0.00029 20.5 0.0 2.5 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.19 OAP56121.1 - 3e-09 36.9 0.0 0.00013 21.8 0.0 2.4 2 0 0 2 2 2 2 AraC-like ligand binding domain Cupin_3 PF05899.12 OAP56121.1 - 6.6e-08 32.1 0.0 0.0072 16.0 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) Cupin_6 PF12852.7 OAP56121.1 - 0.0023 17.7 0.0 1.2 8.9 0.0 2.3 2 0 0 2 2 2 2 Cupin EutQ PF06249.12 OAP56121.1 - 0.0069 16.2 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Transp_cyt_pur PF02133.15 OAP56122.1 - 2.7e-22 79.2 37.3 5.2e-22 78.2 37.3 1.4 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Abhydrolase_1 PF00561.20 OAP56124.1 - 2.9e-12 46.8 0.0 1.9e-10 40.8 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAP56124.1 - 4.5e-08 34.0 0.5 5.6e-08 33.7 0.5 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.14 OAP56124.1 - 0.00053 18.8 0.0 0.00075 18.3 0.0 1.1 1 0 0 1 1 1 1 Ndr family Hydrolase_4 PF12146.8 OAP56124.1 - 0.00089 18.6 0.0 0.0012 18.1 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF3176 PF11374.8 OAP56125.1 - 2.5e-31 108.1 0.6 2.5e-31 108.1 0.6 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) His_Phos_1 PF00300.22 OAP56125.1 - 0.076 12.7 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) ADH_N PF08240.12 OAP56126.1 - 1.9e-27 95.3 0.5 1.9e-27 95.3 0.5 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAP56126.1 - 1.8e-14 53.8 0.0 2.7e-14 53.3 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 OAP56126.1 - 0.00015 21.3 0.8 0.02 14.4 0.4 2.7 2 1 0 2 2 2 2 Glucose dehydrogenase C-terminus NCD3G PF07562.14 OAP56126.1 - 0.06 13.3 0.2 0.13 12.2 0.2 1.5 1 0 0 1 1 1 0 Nine Cysteines Domain of family 3 GPCR 2-Hacid_dh_C PF02826.19 OAP56127.1 - 1.1e-40 138.9 0.0 1.8e-40 138.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 OAP56127.1 - 5.3e-08 32.6 0.0 9.2e-08 31.8 0.0 1.5 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Peptidase_M20 PF01546.28 OAP56128.1 - 3.6e-21 75.8 0.1 5.6e-21 75.2 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 OAP56128.1 - 4.9e-13 49.0 0.0 9.5e-13 48.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain SET PF00856.28 OAP56129.1 - 5.9e-15 56.1 3.4 1.2e-14 55.1 0.4 2.9 2 1 0 2 2 2 1 SET domain AWS PF17907.1 OAP56129.1 - 4e-06 26.8 7.4 4e-06 26.8 7.4 2.3 3 0 0 3 3 3 1 AWS domain DHHC PF01529.20 OAP56130.1 - 1.3e-34 119.2 7.0 1.3e-34 119.2 7.0 1.9 2 0 0 2 2 2 1 DHHC palmitoyltransferase B12D PF06522.11 OAP56131.1 - 0.0017 18.1 0.0 0.0026 17.5 0.0 1.3 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit SMP PF04927.12 OAP56132.1 - 0.091 13.3 0.1 0.78 10.3 0.0 2.2 2 0 0 2 2 2 0 Seed maturation protein Coq4 PF05019.13 OAP56133.1 - 7.4e-85 283.8 0.0 8.8e-85 283.5 0.0 1.1 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 GyrI-like PF06445.15 OAP56133.1 - 0.017 15.4 0.1 0.41 11.0 0.0 2.1 2 0 0 2 2 2 0 GyrI-like small molecule binding domain dsDNA_bind PF01984.20 OAP56134.1 - 4.9e-36 123.4 11.0 6.7e-36 123.0 11.0 1.2 1 0 0 1 1 1 1 Double-stranded DNA-binding domain Med4 PF10018.9 OAP56134.1 - 0.1 12.2 5.6 0.19 11.4 1.5 2.0 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 DUF4615 PF15393.6 OAP56134.1 - 0.3 11.6 2.6 0.23 12.0 1.2 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4615) Sec2p PF06428.11 OAP56135.1 - 1.7e-26 92.0 10.1 1.7e-26 92.0 10.1 2.4 1 1 0 2 2 2 1 GDP/GTP exchange factor Sec2p DUF812 PF05667.11 OAP56135.1 - 0.017 14.1 13.3 0.025 13.5 13.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Bac_DnaA PF00308.18 OAP56135.1 - 0.026 14.3 0.5 0.047 13.5 0.5 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein DUF5339 PF17274.2 OAP56135.1 - 0.033 15.1 0.6 0.033 15.1 0.6 3.4 3 0 0 3 3 3 0 Family of unknown function (DUF5339) Fib_alpha PF08702.10 OAP56135.1 - 0.037 14.2 12.9 2.1 8.6 4.2 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF3584 PF12128.8 OAP56135.1 - 0.037 11.6 19.2 0.054 11.0 19.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_13 PF13166.6 OAP56135.1 - 0.096 11.3 10.5 0.18 10.4 10.5 1.3 1 0 0 1 1 1 0 AAA domain GCN5L1 PF06320.13 OAP56135.1 - 0.29 11.3 8.8 0.16 12.2 4.1 2.4 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) tRNA-synt_2c PF01411.19 OAP56135.1 - 1.6 7.2 5.2 2.3 6.6 5.2 1.1 1 0 0 1 1 1 0 tRNA synthetases class II (A) Golgin_A5 PF09787.9 OAP56135.1 - 1.6 8.1 17.3 2.8 7.3 17.3 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 ABC_tran_CTD PF16326.5 OAP56135.1 - 2.4 8.5 20.2 1.1 9.5 7.4 3.9 3 1 1 4 4 3 0 ABC transporter C-terminal domain ADIP PF11559.8 OAP56135.1 - 3.2 7.8 22.9 2.5 8.2 11.2 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding SlyX PF04102.12 OAP56135.1 - 6.5 7.4 14.0 2.7 8.7 2.1 3.4 1 1 1 3 3 3 0 SlyX DUF3450 PF11932.8 OAP56135.1 - 9 5.5 21.2 0.94 8.7 2.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Questin_oxidase PF14027.6 OAP56136.1 - 3.4e-89 299.7 2.9 4.2e-89 299.4 2.9 1.1 1 0 0 1 1 1 1 Questin oxidase-like Defensin_propep PF00879.18 OAP56136.1 - 0.14 12.4 0.1 0.33 11.3 0.1 1.6 1 0 0 1 1 1 0 Defensin propeptide Methyltransf_31 PF13847.6 OAP56137.1 - 5.7e-29 100.9 0.0 8.1e-29 100.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAP56137.1 - 4.5e-26 91.3 0.0 7.5e-26 90.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAP56137.1 - 8.5e-25 87.3 0.0 1.6e-24 86.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAP56137.1 - 1.2e-17 64.0 0.0 1.6e-17 63.6 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 OAP56137.1 - 3.6e-16 59.7 0.0 6.2e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAP56137.1 - 2.2e-15 56.9 0.0 2.8e-15 56.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 OAP56137.1 - 6.6e-11 42.2 0.0 8.6e-11 41.8 0.0 1.1 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_4 PF02390.17 OAP56137.1 - 2.2e-07 30.5 0.0 7.5e-07 28.8 0.0 1.8 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_29 PF03141.16 OAP56137.1 - 4.3e-06 25.6 0.0 5.7e-06 25.2 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase DREV PF05219.12 OAP56137.1 - 4.7e-06 25.9 0.0 6.3e-06 25.5 0.0 1.1 1 0 0 1 1 1 1 DREV methyltransferase MTS PF05175.14 OAP56137.1 - 5.3e-06 26.1 0.0 7.4e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_9 PF08003.11 OAP56137.1 - 1.2e-05 24.5 0.0 1.5e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_8 PF05148.15 OAP56137.1 - 7.4e-05 22.7 0.0 0.0016 18.3 0.0 2.1 1 1 0 1 1 1 1 Hypothetical methyltransferase PCMT PF01135.19 OAP56137.1 - 8.8e-05 22.4 0.0 0.00012 22.0 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_2 PF00891.18 OAP56137.1 - 0.0001 21.7 0.0 0.00012 21.4 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase domain NodS PF05401.11 OAP56137.1 - 0.0012 18.5 0.0 0.0018 17.9 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_PK PF05891.12 OAP56137.1 - 0.0017 17.9 0.0 0.0025 17.4 0.0 1.3 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase TehB PF03848.14 OAP56137.1 - 0.0039 16.6 0.0 0.0054 16.2 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltr_RsmB-F PF01189.17 OAP56137.1 - 0.0039 16.9 0.0 0.0073 16.0 0.0 1.4 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F CheR PF01739.18 OAP56137.1 - 0.0073 15.8 0.0 0.028 13.9 0.0 1.8 1 1 1 2 2 2 1 CheR methyltransferase, SAM binding domain Methyltransf_18 PF12847.7 OAP56137.1 - 0.0099 15.8 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 OAP56137.1 - 0.023 14.1 0.0 0.031 13.7 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) YAcAr PF10686.9 OAP56137.1 - 0.071 13.1 1.5 5.8 6.9 0.5 3.2 3 0 0 3 3 3 0 YspA, cpYpsA-related SLOG family RAMA PF18755.1 OAP56137.1 - 0.13 12.7 2.3 0.32 11.4 0.5 2.4 3 0 0 3 3 2 0 Restriction Enzyme Adenine Methylase Associated DUF3336 PF11815.8 OAP56138.1 - 1.7e-24 86.1 0.0 6.9e-23 80.9 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) Patatin PF01734.22 OAP56138.1 - 4.5e-10 40.1 0.5 1.1e-09 38.8 0.2 1.7 2 1 0 2 2 2 1 Patatin-like phospholipase RNase_H_2 PF13482.6 OAP56138.1 - 0.097 12.7 0.4 4.8 7.2 0.0 2.3 2 0 0 2 2 2 0 RNase_H superfamily Dicty_REP PF05086.12 OAP56139.1 - 0.49 8.3 3.2 0.62 8.0 3.2 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Methyltransf_25 PF13649.6 OAP56140.1 - 3.9e-20 72.3 0.2 1.5e-19 70.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAP56140.1 - 1.5e-19 70.3 0.0 3.3e-19 69.2 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAP56140.1 - 5.9e-17 61.8 0.0 1.6e-16 60.4 0.0 1.7 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 OAP56140.1 - 1.6e-16 60.7 0.0 3.4e-16 59.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAP56140.1 - 5.4e-13 49.1 0.0 8.2e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAP56140.1 - 1.4e-12 48.2 0.0 2.8e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 OAP56140.1 - 3.4e-08 33.5 0.1 1.1e-07 31.8 0.0 1.8 2 1 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 OAP56140.1 - 1.2e-05 25.0 0.2 4.6e-05 23.0 0.1 2.0 2 0 0 2 2 2 1 Methyltransferase small domain PrmA PF06325.13 OAP56140.1 - 0.00023 20.7 0.1 0.00039 19.9 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.20 OAP56140.1 - 0.00041 19.7 0.6 0.0018 17.7 0.1 2.1 2 1 0 2 2 2 1 Mycolic acid cyclopropane synthetase UPF0020 PF01170.18 OAP56140.1 - 0.0036 17.0 0.1 0.13 12.0 0.1 2.5 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 FtsJ PF01728.19 OAP56140.1 - 0.0042 17.2 0.0 0.0095 16.1 0.0 1.7 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_32 PF13679.6 OAP56140.1 - 0.035 14.1 0.0 0.057 13.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DUF5411 PF17424.2 OAP56140.1 - 0.1 12.5 0.2 0.16 12.0 0.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5411) adh_short_C2 PF13561.6 OAP56141.1 - 1.8e-58 197.9 1.0 2.3e-58 197.5 1.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP56141.1 - 2.6e-44 151.0 2.4 3.3e-44 150.7 2.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAP56141.1 - 0.00017 21.6 0.3 0.00025 21.0 0.3 1.3 1 0 0 1 1 1 1 KR domain Methyltransf_25 PF13649.6 OAP56141.1 - 0.0058 17.3 0.0 0.013 16.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAP56141.1 - 0.066 13.9 0.0 0.15 12.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Fungal_trans PF04082.18 OAP56142.1 - 5.9e-17 61.6 0.0 9.3e-17 60.9 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP56142.1 - 0.0037 17.4 3.1 0.0064 16.6 3.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.24 OAP56143.1 - 3.5e-92 309.6 23.2 4.4e-92 309.3 23.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP56143.1 - 3.9e-23 81.9 32.0 1.1e-22 80.5 28.3 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 OAP56143.1 - 0.00028 19.5 1.3 0.00028 19.5 1.3 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) FMO-like PF00743.19 OAP56144.1 - 4.1e-15 55.2 0.0 9.9e-15 53.9 0.0 1.5 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 OAP56144.1 - 3.2e-05 23.3 0.0 0.00014 21.1 0.0 2.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 OAP56144.1 - 0.00021 21.5 0.0 0.00064 19.9 0.0 1.9 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAP56144.1 - 0.00027 20.3 0.0 2.2 7.5 0.0 3.1 3 0 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAP56144.1 - 0.007 15.7 0.0 0.023 14.0 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AA_permease_2 PF13520.6 OAP56145.1 - 1.1e-47 162.9 50.5 1.4e-47 162.5 50.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAP56145.1 - 1.7e-19 69.8 45.5 2.2e-19 69.4 45.5 1.1 1 0 0 1 1 1 1 Amino acid permease Amino_oxidase PF01593.24 OAP56146.1 - 1e-57 196.5 0.0 1.5e-57 195.9 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Ribonuc_L-PSP PF01042.21 OAP56146.1 - 2.2e-17 63.2 0.0 4.5e-17 62.2 0.0 1.5 1 0 0 1 1 1 1 Endoribonuclease L-PSP NAD_binding_8 PF13450.6 OAP56146.1 - 1.6e-13 50.6 0.2 8.5e-13 48.3 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAP56146.1 - 2.8e-07 30.5 1.9 2.8e-06 27.2 2.0 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 OAP56146.1 - 3e-07 30.2 0.1 5.8e-07 29.2 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OAP56146.1 - 3e-06 26.6 0.5 6.8e-06 25.4 0.4 1.6 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 OAP56146.1 - 3.7e-05 22.6 0.2 0.0025 16.6 0.1 2.3 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 OAP56146.1 - 5.3e-05 22.5 1.0 8.6e-05 21.8 0.1 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.17 OAP56146.1 - 0.00024 20.5 0.0 0.00041 19.7 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 OAP56146.1 - 0.00025 20.4 0.3 0.00065 19.0 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OAP56146.1 - 0.00049 19.2 0.1 0.093 11.8 0.1 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein FAD_binding_3 PF01494.19 OAP56146.1 - 0.0011 18.3 0.2 0.0016 17.7 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 OAP56146.1 - 0.0015 17.9 0.1 0.034 13.4 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAP56146.1 - 0.0025 18.4 0.0 0.0084 16.7 0.0 2.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAP56146.1 - 0.019 14.9 0.4 6.8 6.7 0.0 2.7 3 0 0 3 3 2 0 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 OAP56146.1 - 0.12 11.6 0.3 0.57 9.4 0.1 2.1 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Fungal_trans_2 PF11951.8 OAP56147.1 - 1.3e-34 119.7 0.3 1.8e-34 119.2 0.3 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP56147.1 - 2.8e-07 30.5 6.7 5.5e-07 29.6 6.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CorA PF01544.18 OAP56148.1 - 2e-06 27.3 0.3 4e-06 26.3 0.3 1.5 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein KGG PF10685.9 OAP56149.1 - 2.4 8.6 11.1 0.93 9.9 7.1 2.5 2 1 0 2 2 2 0 Stress-induced bacterial acidophilic repeat motif Homeodomain PF00046.29 OAP56150.1 - 2.2e-16 59.5 3.0 6.9e-16 57.8 3.0 1.9 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 OAP56150.1 - 0.00049 20.0 0.4 0.00049 20.0 0.4 2.1 2 0 0 2 2 2 1 Homeobox KN domain DUF4638 PF15472.6 OAP56150.1 - 0.084 12.6 1.2 0.17 11.6 1.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) HAD_2 PF13419.6 OAP56151.1 - 9.6e-20 71.4 0.0 1.3e-19 71.0 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OAP56151.1 - 2e-07 31.5 0.2 2.1e-05 24.9 0.0 2.4 2 1 0 3 3 3 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OAP56151.1 - 0.0051 16.8 0.0 0.0094 16.0 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 OAP56151.1 - 0.017 15.5 0.0 0.035 14.5 0.0 1.5 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase TetR_C_3 PF08362.11 OAP56151.1 - 0.13 12.2 0.0 0.33 10.9 0.0 1.6 1 0 0 1 1 1 0 YcdC-like protein, C-terminal region GN3L_Grn1 PF08701.11 OAP56152.1 - 6.5e-25 87.0 16.5 6.5e-25 87.0 16.5 1.9 2 0 0 2 2 1 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.23 OAP56152.1 - 6.5e-17 61.7 0.1 4.6e-13 49.3 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OAP56152.1 - 2.1e-09 37.5 0.0 7.2e-09 35.8 0.0 1.8 1 1 0 1 1 1 1 RsgA GTPase FeoB_N PF02421.18 OAP56152.1 - 2.4e-06 27.2 0.1 0.00011 21.8 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 OAP56152.1 - 0.00013 21.6 0.0 0.069 12.7 0.0 2.7 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 OAP56152.1 - 0.00032 20.8 4.7 0.48 10.5 0.2 3.5 3 1 0 3 3 3 2 Dynamin family MeaB PF03308.16 OAP56152.1 - 0.0049 15.9 1.0 0.012 14.6 0.0 2.1 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB RNA_pol_3_Rpc31 PF11705.8 OAP56152.1 - 0.0099 16.2 17.8 0.019 15.2 17.8 1.5 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Roc PF08477.13 OAP56152.1 - 0.01 16.1 0.0 4.7 7.4 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_18 PF13238.6 OAP56152.1 - 0.024 15.2 2.2 0.22 12.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 OAP56152.1 - 0.047 13.3 0.0 0.44 10.1 0.0 2.3 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF2574 PF10836.8 OAP56152.1 - 0.099 12.5 0.0 0.54 10.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2574) Cwf_Cwc_15 PF04889.12 OAP56152.1 - 0.46 10.2 16.2 0.87 9.3 16.2 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein TFIIA PF03153.13 OAP56152.1 - 1.7 8.5 9.7 3 7.7 9.7 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2277 PF10041.9 OAP56152.1 - 2.3 8.6 4.8 5.9 7.3 0.1 3.0 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2277) CBFD_NFYB_HMF PF00808.23 OAP56153.1 - 1.6e-06 28.3 0.0 2.9e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 OAP56153.1 - 0.015 15.7 0.0 0.015 15.7 0.0 2.9 3 1 0 3 3 3 0 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.13 OAP56153.1 - 0.022 14.8 0.1 0.034 14.2 0.1 1.3 1 0 0 1 1 1 0 Bromodomain associated Nop14 PF04147.12 OAP56153.1 - 0.24 9.6 43.7 0.33 9.1 43.7 1.3 1 0 0 1 1 1 0 Nop14-like family Lactamase_B PF00753.27 OAP56154.1 - 1.3e-08 35.1 4.2 1.4e-07 31.7 3.1 2.9 1 1 1 2 2 2 1 Metallo-beta-lactamase superfamily Proteasom_Rpn13 PF04683.13 OAP56155.1 - 1.1e-24 86.7 0.0 2.3e-24 85.7 0.0 1.5 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor RPN13_C PF16550.5 OAP56155.1 - 5.3e-10 39.5 1.7 2.1e-08 34.3 0.9 2.9 2 1 0 2 2 2 1 UCH-binding domain DUF1542 PF07564.11 OAP56155.1 - 0.015 15.4 0.5 0.026 14.6 0.5 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1542) Ribosomal_L6e PF01159.19 OAP56156.1 - 2.6e-40 137.4 0.2 3.7e-40 136.9 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L6e FA_hydroxylase PF04116.13 OAP56157.1 - 1.5e-13 51.2 1.9 1.5e-13 51.2 1.9 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily zf-C2H2 PF00096.26 OAP56158.1 - 3.8e-06 27.0 8.5 4.2e-05 23.8 0.6 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAP56158.1 - 0.039 14.8 6.4 0.3 12.0 0.4 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger FOXP-CC PF16159.5 OAP56158.1 - 1.1 9.9 7.8 1 10.1 0.5 2.6 2 1 1 3 3 3 0 FOXP coiled-coil domain zf-C2H2_6 PF13912.6 OAP56158.1 - 4.3 7.4 6.8 1.3 9.1 0.2 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger BCNT PF07572.12 OAP56160.1 - 1.2e-23 83.0 1.1 1.2e-23 83.0 1.1 1.7 2 0 0 2 2 2 1 Bucentaur or craniofacial development RPE65 PF03055.15 OAP56161.1 - 9.4e-108 361.4 0.0 1.1e-107 361.2 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein ELO PF01151.18 OAP56162.1 - 3.9e-81 272.3 9.8 5e-81 271.9 9.8 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family Apolipoprotein PF01442.18 OAP56162.1 - 0.0001 22.2 26.1 0.0001 22.2 26.1 2.5 1 1 1 2 2 2 1 Apolipoprotein A1/A4/E domain LEA_4 PF02987.16 OAP56162.1 - 0.017 15.2 1.5 0.017 15.2 1.5 4.5 4 2 1 5 5 5 0 Late embryogenesis abundant protein YtxH PF12732.7 OAP56162.1 - 4.7 7.8 45.6 0.52 10.9 5.6 5.2 2 1 2 4 4 4 0 YtxH-like protein Mtc PF03820.17 OAP56163.1 - 3.3e-121 404.1 0.2 3.8e-121 403.9 0.2 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier PhyH PF05721.13 OAP56164.1 - 7.7e-18 65.5 0.0 1.3e-17 64.7 0.0 1.4 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) SCP2 PF02036.17 OAP56164.1 - 0.0052 17.3 0.0 0.013 15.9 0.0 1.7 1 1 0 1 1 1 1 SCP-2 sterol transfer family 2OG-FeII_Oxy_5 PF13759.6 OAP56164.1 - 0.053 13.9 0.0 0.24 11.8 0.0 2.1 2 1 0 2 2 2 0 Putative 2OG-Fe(II) oxygenase 2OG-FeII_Oxy_3 PF13640.6 OAP56164.1 - 0.081 13.8 0.0 0.17 12.8 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily DUF3425 PF11905.8 OAP56165.1 - 2.9e-13 49.9 0.0 1.4e-12 47.7 0.0 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 OAP56165.1 - 0.0033 17.5 7.2 0.0033 17.5 7.2 2.3 2 0 0 2 2 2 1 bZIP transcription factor PKcGMP_CC PF16808.5 OAP56165.1 - 0.019 14.8 2.5 3.9 7.4 0.3 2.5 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Cnn_1N PF07989.11 OAP56165.1 - 0.15 12.2 1.9 0.3 11.3 1.9 1.4 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 Jnk-SapK_ap_N PF09744.9 OAP56165.1 - 0.17 12.1 5.1 0.27 11.5 5.1 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 A_deaminase PF00962.22 OAP56166.1 - 2.1e-22 79.9 0.0 4.9e-22 78.7 0.0 1.6 1 0 0 1 1 1 1 Adenosine/AMP deaminase Mt_ATP-synt_B PF05405.14 OAP56166.1 - 0.067 12.8 0.1 0.12 11.9 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) RXT2_N PF08595.11 OAP56166.1 - 0.42 10.6 3.7 0.82 9.7 3.7 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal Sigma70_ner PF04546.13 OAP56166.1 - 1.4 8.8 10.6 2.6 7.9 8.1 2.3 2 1 0 2 2 2 0 Sigma-70, non-essential region RNA_pol_3_Rpc31 PF11705.8 OAP56166.1 - 2.2 8.5 15.2 3.9 7.7 15.2 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Nop14 PF04147.12 OAP56166.1 - 3.8 5.6 10.7 5.6 5.1 10.7 1.2 1 0 0 1 1 1 0 Nop14-like family ATG2_CAD PF13329.6 OAP56167.1 - 9.7e-37 126.1 0.0 2.5e-36 124.8 0.0 1.8 1 0 0 1 1 1 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.11 OAP56167.1 - 6.4e-30 103.4 1.3 1.6e-29 102.1 0.2 2.2 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain VPS13_C PF16909.5 OAP56167.1 - 0.024 14.4 0.0 0.056 13.2 0.0 1.6 1 0 0 1 1 1 0 Vacuolar-sorting-associated 13 protein C-terminal VWA PF00092.28 OAP56168.1 - 5.9e-05 23.4 0.0 0.00015 22.1 0.0 1.6 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 OAP56168.1 - 0.00059 20.5 0.0 0.0012 19.5 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain SOG2 PF10428.9 OAP56168.1 - 0.28 10.3 6.2 0.33 10.1 6.2 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein KAR9 PF08580.10 OAP56168.1 - 1.8 7.0 11.0 2.2 6.7 11.0 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Raptor_N PF14538.6 OAP56169.1 - 1.5e-62 209.9 0.0 2.6e-62 209.1 0.0 1.4 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.32 OAP56169.1 - 4.4e-06 27.3 5.1 2.7 9.0 0.0 6.4 6 0 0 6 6 6 1 WD domain, G-beta repeat BBS2_Mid PF14783.6 OAP56169.1 - 0.0043 17.1 0.1 2.7 8.1 0.0 2.8 1 1 1 2 2 2 2 Ciliary BBSome complex subunit 2, middle region HEAT PF02985.22 OAP56169.1 - 0.18 12.2 2.6 2.1 8.9 0.0 3.9 4 0 0 4 4 4 0 HEAT repeat Kelch_4 PF13418.6 OAP56170.1 - 3e-30 104.0 11.2 1.7e-05 24.8 0.1 6.5 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.6 OAP56170.1 - 3.9e-29 100.4 13.9 2.9e-07 30.6 0.1 6.5 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.6 OAP56170.1 - 3.3e-28 97.1 7.3 5.5e-06 26.2 0.1 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 OAP56170.1 - 6.2e-28 96.1 6.8 3e-08 33.6 0.8 6.4 5 1 1 6 6 6 5 Kelch motif Kelch_1 PF01344.25 OAP56170.1 - 7.3e-28 95.9 1.1 1.5e-07 30.9 0.2 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.15 OAP56170.1 - 3e-20 71.3 4.4 8.7e-06 25.5 0.1 6.6 6 0 0 6 6 6 5 Kelch motif Fez1 PF06818.15 OAP56170.1 - 0.00049 20.6 12.4 0.00049 20.6 12.4 6.1 2 2 3 5 5 5 2 Fez1 GAS PF13851.6 OAP56170.1 - 0.0029 17.0 10.8 0.0029 17.0 10.8 6.5 4 3 2 6 6 6 3 Growth-arrest specific micro-tubule binding bZIP_2 PF07716.15 OAP56170.1 - 0.0065 16.5 3.9 0.0065 16.5 3.9 6.2 6 1 1 7 7 7 1 Basic region leucine zipper Filament PF00038.21 OAP56170.1 - 3.2 7.2 99.7 0.51 9.9 6.8 6.4 2 1 3 5 5 5 0 Intermediate filament protein A_deaminase PF00962.22 OAP56171.1 - 1e-51 176.3 0.0 1.2e-51 176.1 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase DUF2063 PF09836.9 OAP56171.1 - 0.034 14.4 0.0 0.08 13.2 0.0 1.6 1 0 0 1 1 1 0 Putative DNA-binding domain RAI16-like PF10257.9 OAP56172.1 - 1.3e-67 228.3 0.0 2.4e-67 227.4 0.0 1.5 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein Phage_holin_3_6 PF07332.11 OAP56173.1 - 0.025 14.6 2.4 0.025 14.6 2.4 2.3 2 1 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III CBFD_NFYB_HMF PF00808.23 OAP56174.1 - 2.2e-15 56.7 1.0 4e-15 55.8 1.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 OAP56174.1 - 0.00017 22.0 0.6 0.00017 22.0 0.6 2.0 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.10 OAP56174.1 - 1.1 9.6 3.6 0.7 10.3 0.3 2.1 2 0 0 2 2 2 0 CENP-S associating Centromere protein X Abhydrolase_3 PF07859.13 OAP56175.1 - 3.3e-21 76.1 0.0 4.1e-21 75.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 OAP56175.1 - 1.8e-15 56.7 0.0 4.2e-15 55.5 0.0 1.4 1 1 0 1 1 1 1 Steryl acetyl hydrolase zf-RING_6 PF14835.6 OAP56176.1 - 0.011 15.6 6.5 0.019 14.8 6.5 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Prok-RING_4 PF14447.6 OAP56176.1 - 0.59 10.0 11.9 1.1 9.2 11.9 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 OAP56176.1 - 2.8 7.9 11.5 4.5 7.2 11.5 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TPR_12 PF13424.6 OAP56177.1 - 4.5e-26 90.9 22.2 3e-12 46.7 0.7 4.9 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.6 OAP56177.1 - 1.1e-15 56.9 15.0 2.8e-07 30.2 0.2 6.3 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_MalT PF17874.1 OAP56177.1 - 3.7e-06 26.5 4.3 3.7e-06 26.5 4.3 2.2 2 1 0 2 2 2 1 MalT-like TPR region TPR_8 PF13181.6 OAP56177.1 - 1.7e-05 24.7 0.0 0.088 13.1 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 OAP56177.1 - 0.00016 21.5 1.0 0.16 12.1 0.0 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat NB-ARC PF00931.22 OAP56177.1 - 0.00017 20.9 0.0 0.00042 19.6 0.0 1.7 1 1 0 1 1 1 1 NB-ARC domain TPR_7 PF13176.6 OAP56177.1 - 0.00027 20.7 3.1 0.0046 16.9 0.1 4.3 6 0 0 6 6 6 1 Tetratricopeptide repeat AAA_16 PF13191.6 OAP56177.1 - 0.0017 18.8 1.5 0.0071 16.7 0.0 2.8 2 1 0 2 2 2 1 AAA ATPase domain TPR_4 PF07721.14 OAP56177.1 - 0.0038 17.7 1.0 0.0038 17.7 1.0 5.5 6 0 0 6 6 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 OAP56177.1 - 0.02 14.7 0.0 0.21 11.4 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat AAA_22 PF13401.6 OAP56177.1 - 0.021 15.1 0.0 0.64 10.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain TPR_19 PF14559.6 OAP56177.1 - 0.04 14.4 7.2 1.6 9.3 0.0 3.9 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 OAP56177.1 - 0.21 12.5 12.9 0.47 11.4 0.0 6.0 5 2 1 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 OAP56177.1 - 1.1 10.1 3.3 24 5.8 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_20 PF14561.6 OAP56177.1 - 1.1 9.6 7.7 5.6 7.4 0.1 3.9 2 1 1 4 4 4 0 Tetratricopeptide repeat Acyltransferase PF01553.21 OAP56178.1 - 0.019 14.6 0.0 0.058 13.0 0.0 1.7 1 1 0 1 1 1 0 Acyltransferase DLIC PF05783.11 OAP56178.1 - 0.077 11.8 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Aminotran_5 PF00266.19 OAP56180.1 - 1.7e-55 188.5 0.0 2e-55 188.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 OAP56180.1 - 1.7e-05 23.6 0.0 4e-05 22.3 0.0 1.5 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 OAP56180.1 - 5.3e-05 22.5 0.0 7.6e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Kinesin PF00225.23 OAP56182.1 - 2.1e-103 345.8 4.0 4.7e-103 344.6 4.0 1.6 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 OAP56182.1 - 1.7e-60 203.3 1.6 2.2e-60 203.0 0.1 2.0 2 0 0 2 2 2 1 Microtubule binding AAA_16 PF13191.6 OAP56182.1 - 0.062 13.7 0.0 0.062 13.7 0.0 3.2 2 1 0 2 2 2 0 AAA ATPase domain TFIID_NTD2 PF04494.15 OAP56182.1 - 3.2 8.0 7.9 0.43 10.8 2.9 2.2 2 0 0 2 2 2 0 WD40 associated region in TFIID subunit, NTD2 domain Filament PF00038.21 OAP56182.1 - 8.9 5.8 50.6 0.74 9.3 7.2 4.1 2 1 2 4 4 4 0 Intermediate filament protein GMC_oxred_N PF00732.19 OAP56183.1 - 3.3e-43 148.2 0.1 4.4e-43 147.7 0.1 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAP56183.1 - 2.1e-26 93.1 0.7 6.7e-26 91.5 0.5 2.0 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.24 OAP56183.1 - 3.5e-05 23.1 2.6 0.014 14.6 0.1 2.5 3 0 0 3 3 3 2 FAD binding domain Pyr_redox_2 PF07992.14 OAP56183.1 - 0.0082 15.4 0.0 0.22 10.7 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAP56183.1 - 0.029 14.6 0.1 0.1 12.9 0.1 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 OAP56183.1 - 0.2 10.9 0.6 0.44 9.7 0.1 1.8 2 0 0 2 2 2 0 FAD binding domain Dus PF01207.17 OAP56184.1 - 1.4e-42 145.9 0.0 1.1e-28 100.2 0.0 2.7 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) zf-CCCH_4 PF18044.1 OAP56184.1 - 0.00012 21.8 0.6 0.00012 21.8 0.6 3.3 4 0 0 4 4 4 2 CCCH-type zinc finger zf-CCCH PF00642.24 OAP56184.1 - 0.0034 17.2 3.0 0.19 11.7 0.4 3.2 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 OAP56184.1 - 0.017 15.2 13.5 0.098 12.8 2.1 3.1 3 0 0 3 3 3 0 Zinc finger domain zf-C2H2_aberr PF17017.5 OAP56185.1 - 0.00051 20.2 1.4 0.03 14.5 0.0 2.3 2 0 0 2 2 2 1 Aberrant zinc-finger zf-C2H2 PF00096.26 OAP56185.1 - 0.00084 19.7 11.8 0.17 12.4 0.5 3.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAP56185.1 - 0.002 18.8 12.8 0.092 13.6 1.5 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OAP56185.1 - 0.041 14.3 16.3 0.052 14.0 1.0 3.5 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_jaz PF12171.8 OAP56185.1 - 0.049 13.9 3.1 1.1 9.7 0.7 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Mg_trans_NIPA PF05653.14 OAP56186.1 - 1.1e-102 343.1 18.5 1.4e-102 342.8 18.5 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA Choline_kinase PF01633.20 OAP56186.1 - 5.9e-56 189.4 0.0 1.6e-55 188.0 0.0 1.8 1 0 0 1 1 1 1 Choline/ethanolamine kinase Choline_kin_N PF04428.14 OAP56186.1 - 1.4e-15 56.7 0.0 4e-15 55.2 0.0 1.9 1 0 0 1 1 1 1 Choline kinase N terminus APH PF01636.23 OAP56186.1 - 0.00063 19.7 0.6 0.00063 19.7 0.6 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family EamA PF00892.20 OAP56186.1 - 0.0015 18.7 7.1 0.0015 18.7 7.1 3.2 3 0 0 3 3 3 1 EamA-like transporter family GWT1 PF06423.12 OAP56187.1 - 1.3e-36 126.0 1.1 1.3e-36 126.0 1.1 2.3 3 0 0 3 3 3 1 GWT1 DUF4818 PF16089.5 OAP56187.1 - 0.0039 17.6 0.5 0.025 15.0 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4818) Colicin_im PF03857.13 OAP56187.1 - 5 7.1 13.1 0.14 12.1 0.5 3.2 3 0 0 3 3 3 0 Colicin immunity protein Fungal_trans PF04082.18 OAP56188.1 - 1.3e-08 34.2 0.2 2.7e-08 33.2 0.2 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP56188.1 - 2.6e-08 33.9 9.8 4.1e-08 33.2 9.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acyl-CoA_dh_1 PF00441.24 OAP56189.1 - 3.3e-39 134.5 5.8 5e-39 133.9 5.8 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 OAP56189.1 - 1.1e-30 106.5 1.5 1.7e-30 106.0 0.1 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 OAP56189.1 - 2.9e-24 85.1 0.1 9.5e-24 83.4 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 OAP56189.1 - 1.6e-16 60.8 0.9 3.1e-16 59.9 0.9 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 OAP56189.1 - 0.0016 18.2 0.0 0.0048 16.6 0.0 1.7 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal AgrD PF05931.11 OAP56189.1 - 0.087 12.9 0.0 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 Staphylococcal AgrD protein Senescence PF06911.12 OAP56190.1 - 2.2e-55 187.8 7.5 3.5e-55 187.2 7.5 1.3 1 0 0 1 1 1 1 Senescence-associated protein Pkinase PF00069.25 OAP56191.1 - 2.2e-64 217.4 0.0 4.2e-64 216.4 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP56191.1 - 4.1e-36 124.6 0.0 3.9e-30 105.0 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 OAP56191.1 - 1.5e-06 27.7 0.0 0.0031 16.9 0.0 2.3 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 OAP56191.1 - 0.0001 22.3 0.0 0.00024 21.1 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OAP56191.1 - 0.012 14.6 0.1 0.02 13.9 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain RIO1 PF01163.22 OAP56191.1 - 0.029 14.0 0.0 0.061 12.9 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 OAP56191.1 - 0.073 12.4 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OAP56191.1 - 1.2 7.8 6.5 0.87 8.3 0.1 2.3 2 0 0 2 2 2 0 Fungal protein kinase Glyco_hydro_31 PF01055.26 OAP56192.1 - 5.9e-151 503.6 3.6 8e-151 503.1 3.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 OAP56192.1 - 1e-31 109.5 0.1 2.2e-31 108.5 0.1 1.6 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 OAP56192.1 - 0.0027 18.0 0.1 0.0027 18.0 0.1 3.0 4 0 0 4 4 4 1 Galactose mutarotase-like DUF5110 PF17137.4 OAP56192.1 - 0.03 14.6 0.0 0.11 12.8 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF5110) Rotavirus_VP7 PF05868.11 OAP56192.1 - 0.13 11.6 0.5 0.4 10.0 0.5 1.9 1 0 0 1 1 1 0 Rotavirus major outer capsid protein VP7 Borrelia_P83 PF05262.11 OAP56193.1 - 1.2e-06 27.3 0.0 2.9e-06 26.1 0.0 1.5 1 1 0 1 1 1 1 Borrelia P83/100 protein SprA-related PF12118.8 OAP56193.1 - 0.81 8.8 16.2 0.055 12.6 10.3 1.9 2 0 0 2 2 2 0 SprA-related family YusW PF14039.6 OAP56194.1 - 0.027 15.0 0.7 0.11 13.1 0.2 2.2 2 0 0 2 2 2 0 YusW-like protein Spectrin PF00435.21 OAP56194.1 - 6 7.4 9.7 0.29 11.6 1.6 2.4 2 0 0 2 2 2 0 Spectrin repeat APG6_N PF17675.1 OAP56194.1 - 7.8 7.0 15.5 0.54 10.8 0.5 3.5 4 0 0 4 4 4 0 Apg6 coiled-coil region PPP4R2 PF09184.11 OAP56195.1 - 5.8e-08 32.7 1.9 2.2e-07 30.8 0.0 2.5 2 1 0 2 2 2 1 PPP4R2 GATA PF00320.27 OAP56196.1 - 4.5e-16 58.1 6.1 8e-16 57.4 6.1 1.4 1 0 0 1 1 1 1 GATA zinc finger PAS_3 PF08447.12 OAP56196.1 - 5.8e-15 55.4 0.0 1.2e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 OAP56196.1 - 2.8e-13 49.8 0.0 5.4e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 OAP56196.1 - 7.6e-11 42.2 0.0 1.6e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 OAP56196.1 - 7.7e-11 42.2 0.0 1.8e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 PAS domain PAS_11 PF14598.6 OAP56196.1 - 2.2e-05 24.6 0.0 4.2e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 PAS domain PAS_8 PF13188.7 OAP56196.1 - 0.0073 16.3 0.0 0.016 15.2 0.0 1.5 1 0 0 1 1 1 1 PAS domain Zn-ribbon_8 PF09723.10 OAP56196.1 - 0.0094 16.1 0.2 0.02 15.0 0.2 1.5 1 0 0 1 1 1 1 Zinc ribbon domain TF_Zn_Ribbon PF08271.12 OAP56196.1 - 0.091 12.3 0.8 0.44 10.1 0.1 2.2 2 0 0 2 2 2 0 TFIIB zinc-binding AAA_23 PF13476.6 OAP56197.1 - 3.7e-34 119.0 4.0 3.7e-34 119.0 4.0 7.9 4 2 2 6 6 4 1 AAA domain SMC_N PF02463.19 OAP56197.1 - 5.7e-18 65.2 13.6 5.1e-09 35.9 0.1 3.1 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 OAP56197.1 - 4.2e-11 43.2 0.0 4.2e-11 43.2 0.0 5.3 2 2 1 3 3 2 1 AAA ATPase domain AAA_21 PF13304.6 OAP56197.1 - 2.3e-09 37.5 15.2 2.7e-05 24.1 0.0 4.0 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 OAP56197.1 - 1.6e-07 31.5 0.0 5.6e-07 29.7 0.0 2.0 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 OAP56197.1 - 2e-05 24.2 0.0 4.3e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain CtIP_N PF10482.9 OAP56197.1 - 0.0056 16.7 3.5 0.0056 16.7 3.5 9.3 5 3 3 9 9 9 2 Tumour-suppressor protein CtIP N-terminal domain CENP-F_leu_zip PF10473.9 OAP56197.1 - 0.011 15.7 5.2 0.011 15.7 5.2 10.9 4 2 7 11 11 9 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ABC_tran PF00005.27 OAP56197.1 - 0.043 14.3 0.0 0.043 14.3 0.0 7.7 3 2 1 4 4 2 0 ABC transporter AAA_16 PF13191.6 OAP56197.1 - 0.055 13.9 0.0 0.055 13.9 0.0 6.1 3 1 1 4 4 3 0 AAA ATPase domain DUF4062 PF13271.6 OAP56197.1 - 4.2 7.8 14.0 3.1 8.3 0.2 5.1 5 1 0 5 5 5 0 Domain of unknown function (DUF4062) Cellulase PF00150.18 OAP56198.1 - 4e-20 72.4 0.8 4.8e-20 72.1 0.2 1.3 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Adap_comp_sub PF00928.21 OAP56199.1 - 5.8e-21 75.1 0.0 9.3e-21 74.4 0.0 1.3 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 OAP56199.1 - 3.4e-08 33.5 0.0 5.5e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain RPM2 PF08579.11 OAP56199.1 - 0.0097 16.3 0.2 0.019 15.3 0.2 1.4 1 0 0 1 1 1 1 Mitochondrial ribonuclease P subunit (RPM2) NPCBM PF08305.11 OAP56199.1 - 0.15 12.3 0.0 0.34 11.1 0.0 1.5 1 0 0 1 1 1 0 NPCBM/NEW2 domain TMEM52 PF14979.6 OAP56200.1 - 0.0068 16.3 0.1 0.023 14.6 0.0 1.8 2 1 0 2 2 2 1 Transmembrane 52 DUF3328 PF11807.8 OAP56200.1 - 0.008 16.0 0.0 0.0083 15.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) TMEM51 PF15345.6 OAP56200.1 - 0.021 14.7 0.1 0.032 14.1 0.0 1.4 1 1 0 1 1 1 0 Transmembrane protein 51 Fe_dep_repr_C PF02742.15 OAP56201.1 - 0.41 10.8 2.0 1.9 8.6 0.2 2.3 2 0 0 2 2 2 0 Iron dependent repressor, metal binding and dimerisation domain DUF2420 PF10336.9 OAP56202.1 - 2.3e-17 63.0 0.0 7.4e-17 61.3 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2420) FTR1 PF03239.14 OAP56203.1 - 6.2e-86 288.3 5.5 7.6e-86 288.0 5.5 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family Cation_efflux PF01545.21 OAP56203.1 - 1.1 8.9 7.6 1.5 8.5 3.7 2.4 2 1 0 2 2 2 0 Cation efflux family Cu-oxidase_2 PF07731.14 OAP56204.1 - 4e-45 152.9 10.0 2.3e-39 134.3 0.5 3.8 3 1 0 3 3 3 3 Multicopper oxidase Cu-oxidase_3 PF07732.15 OAP56204.1 - 1e-41 141.7 4.1 4.8e-40 136.3 0.7 3.1 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase PF00394.22 OAP56204.1 - 5.7e-37 127.3 1.9 5.8e-36 124.0 0.4 2.4 2 0 0 2 2 2 1 Multicopper oxidase C1q PF00386.21 OAP56204.1 - 0.0046 17.2 0.1 0.24 11.6 0.1 2.5 2 0 0 2 2 2 1 C1q domain Nucleos_tra2_C PF07662.13 OAP56205.1 - 4.3e-75 252.1 1.2 4.3e-75 252.1 1.2 2.4 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 OAP56205.1 - 1.3e-24 86.6 3.0 1.3e-24 86.6 3.0 2.9 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.14 OAP56205.1 - 0.051 13.9 10.5 0.047 14.0 5.8 3.2 2 1 0 2 2 2 0 Nucleoside recognition DUF155 PF02582.14 OAP56206.1 - 2.5e-52 177.5 0.1 3.9e-52 176.9 0.1 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 VIT1 PF01988.19 OAP56207.1 - 1.1e-62 211.7 0.3 1.5e-62 211.3 0.3 1.2 1 0 0 1 1 1 1 VIT family Mpv17_PMP22 PF04117.12 OAP56208.1 - 1.1e-13 51.1 0.8 1.1e-13 51.1 0.8 1.7 2 0 0 2 2 2 1 Mpv17 / PMP22 family F-box-like PF12937.7 OAP56210.1 - 3.9e-11 42.7 0.2 8.7e-11 41.5 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAP56210.1 - 6.7e-07 29.0 0.2 1.6e-06 27.8 0.2 1.7 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 OAP56210.1 - 0.022 14.7 0.1 0.078 12.9 0.1 2.0 2 0 0 2 2 2 0 F-box Tyrosinase PF00264.20 OAP56211.1 - 1.5e-42 146.4 0.3 1.9e-42 146.1 0.3 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase Ran_BP1 PF00638.18 OAP56212.1 - 3.2e-13 50.0 0.1 8.9e-13 48.6 0.1 1.8 1 0 0 1 1 1 1 RanBP1 domain NUP50 PF08911.11 OAP56212.1 - 0.00015 22.4 3.2 0.00015 22.4 3.2 8.9 9 2 0 9 9 9 1 NUP50 (Nucleoporin 50 kDa) AMIN PF11741.8 OAP56212.1 - 0.08 13.1 0.5 0.81 9.9 0.2 2.3 1 1 1 2 2 2 0 AMIN domain Ribosomal_L31e PF01198.19 OAP56213.1 - 3.1e-40 136.3 0.3 5.1e-40 135.6 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L31e MS_channel PF00924.18 OAP56213.1 - 0.14 11.7 0.0 0.18 11.3 0.0 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel CN_hydrolase PF00795.22 OAP56214.1 - 1.6e-58 198.1 0.0 1.8e-58 198.0 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase UPF0254 PF06787.11 OAP56215.1 - 0.004 16.9 0.0 0.0067 16.2 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0254) DUF2677 PF10838.8 OAP56216.1 - 0.019 14.9 0.0 0.036 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2677) Acetyltransf_7 PF13508.7 OAP56217.1 - 2.4e-07 31.1 0.0 4.2e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OAP56217.1 - 7.4e-07 29.2 0.0 2.2e-06 27.6 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAP56217.1 - 2.7e-06 27.6 0.0 3.7e-06 27.1 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 OAP56217.1 - 0.0084 16.1 0.0 0.016 15.2 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 OAP56217.1 - 0.01 15.9 0.0 0.022 14.9 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 OAP56217.1 - 0.13 12.3 0.0 0.71 10.0 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain AA_permease_2 PF13520.6 OAP56219.1 - 1.2e-49 169.4 47.9 1.4e-49 169.1 47.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAP56219.1 - 5.7e-26 91.1 38.8 7.7e-26 90.7 38.8 1.1 1 0 0 1 1 1 1 Amino acid permease Methyltransf_23 PF13489.6 OAP56220.1 - 1.4e-19 70.5 0.0 2.2e-19 69.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAP56220.1 - 1.2e-09 38.8 0.0 2.3e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAP56220.1 - 2.6e-06 28.0 0.0 4.4e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAP56220.1 - 8.1e-05 22.5 0.0 0.0013 18.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAP56220.1 - 0.00069 20.3 0.0 0.004 17.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OAP56220.1 - 0.0031 17.1 0.0 0.0097 15.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain PrmA PF06325.13 OAP56220.1 - 0.014 14.8 0.0 0.021 14.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.9 OAP56220.1 - 0.033 13.9 0.0 0.054 13.2 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_4 PF02390.17 OAP56220.1 - 0.044 13.3 0.8 0.091 12.2 0.0 1.9 2 0 0 2 2 2 0 Putative methyltransferase FtsJ PF01728.19 OAP56220.1 - 0.12 12.4 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Sugar_tr PF00083.24 OAP56221.1 - 1e-70 238.9 22.1 2.7e-65 221.0 13.2 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 OAP56221.1 - 1.7e-29 102.8 24.5 6e-29 101.1 20.5 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 OAP56221.1 - 4.3e-07 29.6 1.8 4.3e-07 29.6 1.8 2.0 3 0 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB TRI12 PF06609.13 OAP56221.1 - 8.9e-06 24.4 1.1 8.9e-06 24.4 1.1 2.3 3 0 0 3 3 3 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 OAP56221.1 - 0.0029 16.0 5.1 0.35 9.1 0.3 2.3 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family DUF3792 PF12670.7 OAP56221.1 - 0.5 10.6 14.2 0.24 11.6 3.1 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3792) TauD PF02668.16 OAP56222.1 - 2.3e-35 122.7 0.0 3e-35 122.3 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Sirohm_synth_C PF14823.6 OAP56222.1 - 0.04 13.6 0.4 0.28 10.8 0.1 2.2 2 0 0 2 2 2 0 Sirohaem biosynthesis protein C-terminal SNF2_N PF00176.23 OAP56223.1 - 1e-53 182.3 0.4 2.2e-53 181.2 0.4 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain VIGSSK PF14773.6 OAP56223.1 - 4.6e-22 77.9 0.3 1.5e-21 76.3 0.3 2.0 1 0 0 1 1 1 1 Helicase-associated putative binding domain, C-terminal Helicase_C PF00271.31 OAP56223.1 - 3.9e-19 69.0 0.0 5.7e-18 65.3 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAP56223.1 - 9.7e-07 28.9 0.0 2.7e-06 27.5 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 OAP56223.1 - 2.2e-05 23.8 0.4 4.6e-05 22.7 0.4 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase DEAD PF00270.29 OAP56223.1 - 0.00043 20.1 0.0 0.00098 18.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF2406 PF10295.9 OAP56223.1 - 0.098 13.3 0.8 0.9 10.3 0.2 2.8 2 0 0 2 2 2 0 Uncharacterised protein (DUF2406) GFA PF04828.14 OAP56224.1 - 4.6e-19 68.6 0.0 6.3e-19 68.1 0.0 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme IBR PF01485.21 OAP56225.1 - 2.5e-09 37.2 36.1 2.5e-06 27.6 8.2 3.8 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain UCR_14kD PF02271.16 OAP56225.1 - 0.18 11.8 0.1 0.18 11.8 0.1 3.5 4 0 0 4 4 4 0 Ubiquinol-cytochrome C reductase complex 14kD subunit zf-ACC PF17848.1 OAP56225.1 - 6.8 6.9 11.6 0.3 11.2 0.4 3.4 3 0 0 3 3 3 0 Acetyl-coA carboxylase zinc finger domain DUF498 PF04430.14 OAP56226.1 - 2e-23 82.5 0.0 3.1e-23 81.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) SPX PF03105.19 OAP56226.1 - 2.6 7.9 8.2 3.3 7.5 8.2 1.1 1 0 0 1 1 1 0 SPX domain Apt1 PF10351.9 OAP56226.1 - 3.3 6.5 5.6 4.3 6.1 5.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 OAP56226.1 - 7.8 4.9 5.4 9.3 4.7 5.4 1.1 1 0 0 1 1 1 0 Macoilin family Glyco_hydro_16 PF00722.21 OAP56227.1 - 1.2e-43 148.7 0.9 2e-43 147.9 0.9 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Chitin_bind_1 PF00187.19 OAP56227.1 - 1.5 9.3 20.1 0.11 13.0 15.0 1.7 2 0 0 2 2 2 0 Chitin recognition protein FAD_binding_3 PF01494.19 OAP56228.1 - 1.1e-45 156.4 0.0 1.4e-45 156.1 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 OAP56228.1 - 0.0033 16.7 0.1 0.02 14.1 0.1 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAP56228.1 - 0.0083 14.9 0.0 0.021 13.6 0.0 1.6 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.6 OAP56228.1 - 0.011 16.0 0.0 0.026 14.8 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 OAP56228.1 - 0.012 14.7 0.2 0.69 8.9 0.1 2.2 1 1 1 2 2 2 0 FAD binding domain Pyr_redox_3 PF13738.6 OAP56228.1 - 0.024 13.9 0.0 0.053 12.8 0.0 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAP56228.1 - 0.036 13.6 0.0 0.6 9.6 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase Sulfotransfer_4 PF17784.1 OAP56229.1 - 2.1e-62 210.8 0.0 2.5e-62 210.5 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OAP56229.1 - 8e-08 32.9 0.6 5.4e-07 30.2 0.6 2.1 1 1 0 1 1 1 1 Sulfotransferase family Alk_phosphatase PF00245.20 OAP56230.1 - 1e-101 340.9 0.0 1.5e-101 340.3 0.0 1.2 1 1 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 OAP56230.1 - 2.4e-05 23.8 0.0 4.8e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily DUF3545 PF12065.8 OAP56230.1 - 0.066 13.2 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3545) DUF1338 PF07063.13 OAP56231.1 - 2e-103 346.0 0.0 2.5e-103 345.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1338) SANTA PF09133.10 OAP56231.1 - 0.11 13.0 0.1 0.51 10.9 0.0 2.2 3 0 0 3 3 3 0 SANTA (SANT Associated) FAD_binding_3 PF01494.19 OAP56232.1 - 5.7e-23 81.7 0.0 5.5e-12 45.6 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.6 OAP56232.1 - 0.00016 21.0 0.1 0.00043 19.6 0.1 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 OAP56232.1 - 0.00018 20.7 0.0 0.0015 17.7 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase Pyr_redox_2 PF07992.14 OAP56232.1 - 0.0017 17.6 0.1 0.022 14.0 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAP56232.1 - 0.0086 16.3 0.0 0.031 14.5 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 OAP56232.1 - 0.097 11.9 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.27 OAP56232.1 - 0.21 12.2 0.3 1.5 9.4 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Fungal_trans PF04082.18 OAP56233.1 - 7.8e-16 57.9 0.0 1.4e-15 57.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP56233.1 - 1.2e-08 34.9 7.9 3.2e-08 33.5 7.9 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyoxalase PF00903.25 OAP56234.1 - 2e-07 31.3 0.1 3.1e-07 30.7 0.1 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF3335 PF11814.8 OAP56234.1 - 0.14 11.6 0.1 0.72 9.3 0.1 1.9 1 1 1 2 2 2 0 Peptidase_C39 like family ADH_zinc_N PF00107.26 OAP56235.1 - 1e-26 93.4 0.0 1.8e-26 92.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAP56235.1 - 3.5e-20 73.4 0.0 5.7e-20 72.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAP56235.1 - 1.9e-07 30.9 0.0 3.8e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 OAP56235.1 - 0.024 14.5 0.0 0.059 13.3 0.0 1.7 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase TrkA_N PF02254.18 OAP56235.1 - 0.13 12.6 0.0 0.26 11.6 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain FAP PF07174.11 OAP56235.1 - 0.42 10.0 1.2 2.4 7.6 0.1 2.0 2 0 0 2 2 2 0 Fibronectin-attachment protein (FAP) COesterase PF00135.28 OAP56236.1 - 2.3e-51 175.2 0.0 3.2e-51 174.8 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAP56236.1 - 0.00033 20.6 0.0 0.00089 19.2 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold adh_short_C2 PF13561.6 OAP56237.1 - 2.2e-37 128.9 0.0 2.4e-37 128.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP56237.1 - 3.8e-33 114.6 0.0 4.7e-33 114.3 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAP56237.1 - 0.0021 18.0 0.0 0.003 17.5 0.0 1.3 1 0 0 1 1 1 1 KR domain p450 PF00067.22 OAP56238.1 - 0.02 13.6 0.0 0.025 13.4 0.0 1.0 1 0 0 1 1 1 0 Cytochrome P450 WD40 PF00400.32 OAP56240.1 - 1.6e-12 47.7 12.4 2.4e-05 25.0 0.1 5.5 5 0 0 5 5 5 3 WD domain, G-beta repeat ABC_membrane PF00664.23 OAP56241.1 - 5e-34 118.2 9.3 5e-34 118.2 9.3 1.7 2 0 0 2 2 2 1 ABC transporter transmembrane region ABC_tran PF00005.27 OAP56241.1 - 5.3e-33 114.4 0.0 1.4e-32 113.0 0.0 1.8 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 OAP56241.1 - 5.3e-06 26.0 1.4 0.00018 21.1 0.0 2.5 2 1 1 3 3 3 1 RecF/RecN/SMC N terminal domain AA_permease_2 PF13520.6 OAP56241.1 - 0.00099 18.0 1.7 0.00099 18.0 1.7 2.3 4 0 0 4 4 4 1 Amino acid permease AAA_16 PF13191.6 OAP56241.1 - 0.0065 16.9 0.4 0.026 14.9 0.3 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 OAP56241.1 - 0.023 14.5 0.1 0.075 12.8 0.1 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 OAP56241.1 - 0.027 14.4 0.0 0.06 13.2 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase SbcCD_C PF13558.6 OAP56241.1 - 0.093 13.0 0.5 2.1 8.6 0.5 2.9 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.6 OAP56241.1 - 0.14 12.4 0.0 0.47 10.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain Pex24p PF06398.11 OAP56241.1 - 0.18 10.8 2.5 0.51 9.3 2.5 1.7 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin XLF PF09302.11 OAP56242.1 - 7.4e-40 137.0 0.5 1.1e-39 136.4 0.5 1.2 1 0 0 1 1 1 1 XLF-Cernunnos, XRcc4-like factor, NHEJ component DUF3433 PF11915.8 OAP56243.1 - 1.3e-09 38.3 2.2 2.9e-09 37.2 2.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3433) DUF3649 PF12365.8 OAP56243.1 - 0.005 16.5 0.1 0.063 13.0 0.1 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3649) Fungal_trans PF04082.18 OAP56247.1 - 1.8e-13 50.2 0.4 2.8e-13 49.5 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cactin_mid PF10312.9 OAP56248.1 - 1.3e-66 224.1 4.6 2.3e-66 223.3 4.6 1.4 1 0 0 1 1 1 1 Conserved mid region of cactin CactinC_cactus PF09732.9 OAP56248.1 - 3.1e-56 188.7 3.2 5.9e-56 187.8 3.2 1.4 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein DUF2839 PF10999.8 OAP56249.1 - 0.031 14.6 0.2 0.031 14.6 0.2 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2839) NDUF_B12 PF08122.12 OAP56249.1 - 0.24 11.5 0.1 0.24 11.5 0.1 3.3 5 0 0 5 5 5 0 NADH-ubiquinone oxidoreductase B12 subunit family Forkhead PF00250.18 OAP56250.1 - 6.7e-17 61.5 0.3 3.2e-16 59.3 0.1 2.2 2 0 0 2 2 2 1 Forkhead domain Foie-gras_1 PF11817.8 OAP56250.1 - 0.1 12.2 0.6 0.22 11.1 0.1 1.8 2 0 0 2 2 2 0 Foie gras liver health family 1 Ribosomal_L34e PF01199.18 OAP56251.1 - 4.1e-42 142.4 1.7 6.4e-42 141.8 1.7 1.3 1 0 0 1 1 1 1 Ribosomal protein L34e Vps36-NZF-N PF16988.5 OAP56251.1 - 0.016 14.6 0.3 0.031 13.7 0.0 1.8 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain FhuF_C PF11575.8 OAP56251.1 - 0.33 10.9 4.4 1.7 8.7 0.3 2.6 2 0 0 2 2 2 0 FhuF 2Fe-2S C-terminal domain PROCN PF08083.11 OAP56252.1 - 2.5e-235 780.7 7.8 2.5e-235 780.7 7.8 2.1 2 0 0 2 2 2 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 OAP56252.1 - 4.5e-127 422.4 2.2 8.5e-127 421.5 2.2 1.5 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 OAP56252.1 - 8.3e-86 285.8 1.3 2e-58 196.9 0.2 2.9 2 0 0 2 2 2 2 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 OAP56252.1 - 1.4e-81 271.8 2.0 3.9e-81 270.4 2.0 1.8 1 0 0 1 1 1 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 OAP56252.1 - 1e-70 236.0 0.1 2.3e-70 234.9 0.1 1.6 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.9 OAP56252.1 - 5e-48 161.4 0.3 1.6e-47 159.8 0.3 2.0 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.11 OAP56252.1 - 2.4e-47 159.9 0.0 8.4e-47 158.1 0.0 2.0 1 0 0 1 1 1 1 PROCT (NUC072) domain Hom_end_hint PF05203.16 OAP56252.1 - 7.6e-08 32.6 1.0 1.6e-07 31.5 0.0 2.0 2 0 0 2 2 2 1 Hom_end-associated Hint DUF3425 PF11905.8 OAP56254.1 - 6.8e-12 45.4 4.1 4.7e-11 42.7 1.2 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3425) ABC_tran_Xtn PF12848.7 OAP56254.1 - 1.1 9.4 6.7 1.1 9.3 4.5 2.0 2 0 0 2 2 2 0 ABC transporter DLH PF01738.18 OAP56255.1 - 2.3e-20 73.1 0.0 2.8e-20 72.8 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 OAP56255.1 - 0.026 14.2 0.0 0.05 13.2 0.0 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold Pro_dh PF01619.18 OAP56257.1 - 1.2e-69 235.2 1.2 1.3e-69 235.0 1.2 1.0 1 0 0 1 1 1 1 Proline dehydrogenase DUF4434 PF14488.6 OAP56257.1 - 0.052 13.6 0.2 0.31 11.0 0.2 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4434) Kinesin PF00225.23 OAP56258.1 - 4.1e-117 390.8 0.0 4.1e-117 390.8 0.0 1.6 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 OAP56258.1 - 1.3e-27 96.5 1.0 1.2e-26 93.4 0.0 2.4 2 0 0 2 2 2 1 Microtubule binding DUF932 PF06067.11 OAP56258.1 - 0.091 12.5 5.0 0.19 11.4 5.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF932) ArgoL2 PF16488.5 OAP56258.1 - 0.22 11.9 0.5 0.6 10.5 0.5 1.8 1 0 0 1 1 1 0 Argonaute linker 2 domain Lipoprotein_6 PF01441.19 OAP56258.1 - 0.32 11.0 5.2 0.24 11.4 2.8 2.0 2 0 0 2 2 2 0 Lipoprotein G0-G1_switch_2 PF15103.6 OAP56258.1 - 0.82 10.1 0.0 0.82 10.1 0.0 3.0 4 0 0 4 4 4 0 G0/G1 switch protein 2 PMSR PF01625.21 OAP56259.1 - 8.7e-58 194.8 0.0 1.1e-57 194.6 0.0 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase IDO PF01231.18 OAP56260.1 - 1.4 7.6 3.2 1.7 7.3 3.2 1.0 1 0 0 1 1 1 0 Indoleamine 2,3-dioxygenase DUF3043 PF11241.8 OAP56260.1 - 6.6 6.7 8.9 9.1 6.3 8.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) adh_short PF00106.25 OAP56261.1 - 1.1e-32 113.1 0.0 1.5e-32 112.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP56261.1 - 8.9e-23 81.1 0.0 1.4e-22 80.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP56261.1 - 6.7e-07 29.4 0.1 2.4e-05 24.3 0.1 2.7 1 1 0 1 1 1 1 KR domain Membr_traf_MHD PF10540.9 OAP56262.1 - 1e-21 77.7 1.3 6.6e-11 42.6 0.3 3.0 1 1 1 2 2 2 2 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.30 OAP56262.1 - 4.4e-14 52.6 0.0 6.8e-13 48.8 0.0 2.6 2 0 0 2 2 2 1 C2 domain DUF810 PF05664.11 OAP56262.1 - 0.0004 19.1 0.8 0.0004 19.1 0.8 2.1 3 0 0 3 3 3 1 Plant family of unknown function (DUF810) Pyr_redox_3 PF13738.6 OAP56263.1 - 1.5e-12 47.4 0.0 6.6e-12 45.3 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 OAP56263.1 - 4.5e-11 41.9 0.0 1.4e-10 40.2 0.0 1.8 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OAP56263.1 - 4.2e-09 36.5 0.0 1.4e-06 28.4 0.0 3.2 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 OAP56263.1 - 1.1e-07 31.4 0.0 7.3e-05 22.1 0.0 2.2 2 0 0 2 2 2 2 Thi4 family Pyr_redox_2 PF07992.14 OAP56263.1 - 3e-07 30.0 0.1 2.2e-05 23.8 0.0 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAP56263.1 - 2e-05 23.9 0.1 0.0007 18.8 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 OAP56263.1 - 0.0001 22.0 0.3 0.012 15.2 0.0 3.1 3 1 1 4 4 4 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 OAP56263.1 - 0.00012 22.6 0.0 0.023 15.2 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAP56263.1 - 0.00082 18.6 0.1 0.056 12.5 0.0 2.8 3 0 0 3 3 3 1 FAD binding domain Shikimate_DH PF01488.20 OAP56263.1 - 0.005 16.9 0.0 0.054 13.6 0.0 2.4 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 OAP56263.1 - 0.0072 16.8 0.0 0.021 15.2 0.0 1.8 2 0 0 2 2 1 1 Putative NAD(P)-binding NAD_binding_9 PF13454.6 OAP56263.1 - 0.011 15.8 0.5 6.3 6.8 0.0 3.0 3 0 0 3 3 3 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 OAP56263.1 - 0.019 14.0 0.1 7.8 5.4 0.0 2.9 3 0 0 3 3 3 0 Lycopene cyclase protein GIDA PF01134.22 OAP56263.1 - 0.036 13.1 0.2 2.6 7.1 0.0 2.5 3 0 0 3 3 3 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 OAP56263.1 - 0.11 11.8 0.0 8.2 5.7 0.0 2.5 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 OAP56263.1 - 0.14 11.5 0.1 0.43 9.9 0.0 1.9 3 0 0 3 3 3 0 FAD dependent oxidoreductase HI0933_like PF03486.14 OAP56263.1 - 0.25 10.0 0.5 4.3 5.9 0.1 2.2 2 0 0 2 2 2 0 HI0933-like protein adh_short PF00106.25 OAP56264.1 - 9.2e-40 136.2 0.5 1.6e-39 135.4 0.5 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP56264.1 - 1e-28 100.5 0.4 1.4e-28 100.0 0.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP56264.1 - 4.1e-08 33.4 3.3 7.6e-07 29.2 3.3 2.1 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 OAP56264.1 - 6.2e-06 25.8 0.1 1e-05 25.1 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.19 OAP56264.1 - 0.0075 15.6 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.17 OAP56264.1 - 0.06 12.4 0.1 0.089 11.9 0.1 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain DFP PF04127.15 OAP56264.1 - 0.087 12.6 0.3 0.25 11.2 0.3 1.7 1 1 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein p450 PF00067.22 OAP56265.1 - 1.5e-62 211.9 0.0 2e-62 211.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.18 OAP56265.1 - 3e-17 62.5 5.4 6.2e-16 58.2 5.4 2.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain Ribosomal_S21e PF01249.18 OAP56266.1 - 4e-42 142.2 0.1 4.4e-42 142.1 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e tRNA-synt_2d PF01409.20 OAP56267.1 - 4.3e-89 298.2 0.0 5.9e-89 297.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 OAP56267.1 - 1.1e-13 51.3 0.3 1.1e-13 51.3 0.3 2.0 2 0 0 2 2 2 1 PheRS DNA binding domain 3 PheRS_DBD2 PF18554.1 OAP56267.1 - 2.9e-06 27.1 0.8 1.3e-05 25.1 0.8 2.2 1 0 0 1 1 1 1 PheRS DNA binding domain 2 tRNA_synthFbeta PF17759.1 OAP56267.1 - 5.5e-06 26.0 0.0 0.0048 16.4 0.0 2.5 2 0 0 2 2 2 2 Phenylalanyl tRNA synthetase beta chain CLM domain tRNA-synt_2 PF00152.20 OAP56267.1 - 3.2e-05 23.2 0.1 0.0031 16.6 0.0 3.1 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.25 OAP56267.1 - 0.053 13.5 0.0 0.14 12.1 0.0 1.8 2 0 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) MFS_1 PF07690.16 OAP56268.1 - 4.1e-57 193.7 35.3 1.2e-48 165.9 19.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAP56268.1 - 5.8e-07 28.7 5.2 5.8e-07 28.7 5.2 3.2 3 0 0 3 3 3 2 Sugar (and other) transporter OATP PF03137.20 OAP56268.1 - 4.7 5.4 14.4 3.9 5.6 5.4 3.0 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Zn_clus PF00172.18 OAP56269.1 - 2.2e-07 30.9 10.4 3.7e-07 30.1 10.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAP56269.1 - 2.2e-06 26.9 0.1 3.3e-06 26.3 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain bZIP_1 PF00170.21 OAP56270.1 - 0.006 16.7 0.1 0.013 15.6 0.1 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 OAP56270.1 - 0.02 15.0 1.8 0.048 13.7 1.8 1.6 1 0 0 1 1 1 0 Basic region leucine zipper adh_short PF00106.25 OAP56271.1 - 1.9e-28 99.3 1.6 2e-28 99.2 1.6 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP56271.1 - 1e-21 77.6 2.3 1.3e-21 77.3 2.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP56271.1 - 1.2e-11 44.9 0.1 1.9e-11 44.2 0.1 1.3 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OAP56271.1 - 2.5e-06 26.9 0.2 2.9e-06 26.6 0.2 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 OAP56271.1 - 0.00078 19.0 0.2 0.0012 18.3 0.2 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 OAP56271.1 - 0.011 15.8 0.0 0.021 14.9 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase OSK PF17182.4 OAP56271.1 - 0.014 14.6 0.0 0.03 13.5 0.0 1.5 2 0 0 2 2 2 0 OSK domain Eno-Rase_NADH_b PF12242.8 OAP56271.1 - 0.11 12.2 1.1 0.19 11.5 0.3 1.8 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Histidinol_dh PF00815.20 OAP56272.1 - 8.9e-160 532.2 1.5 1.2e-159 531.8 1.5 1.2 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.18 OAP56272.1 - 9.4e-24 83.0 0.4 1.9e-23 82.1 0.4 1.5 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.17 OAP56272.1 - 1.3e-15 57.6 0.4 5.6e-15 55.6 0.4 2.1 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase Fungal_trans PF04082.18 OAP56273.1 - 6.1e-09 35.3 0.0 1.2e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP56273.1 - 0.0031 17.6 9.9 0.0059 16.7 9.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 OAP56274.1 - 1e-16 60.8 0.7 2.4e-16 59.5 0.7 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP56274.1 - 0.00052 20.1 6.2 0.00052 20.1 6.2 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DNA_methylase PF00145.17 OAP56275.1 - 1.4e-09 37.7 0.0 8e-08 32.0 0.0 2.6 2 1 0 2 2 2 1 C-5 cytosine-specific DNA methylase Glyco_hydro_64 PF16483.5 OAP56276.1 - 6.1e-141 470.0 0.6 7.1e-141 469.8 0.6 1.0 1 0 0 1 1 1 1 Beta-1,3-glucanase MMM1 PF10296.9 OAP56277.1 - 2.5e-06 26.8 0.0 1.1e-05 24.7 0.0 1.8 2 0 0 2 2 2 1 Maintenance of mitochondrial morphology protein 1 DUF4689 PF15755.5 OAP56277.1 - 6.3 6.3 7.8 2.3 7.8 4.7 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4689) CN_hydrolase PF00795.22 OAP56279.1 - 2.3e-32 112.4 0.0 4.1e-27 95.2 0.0 2.1 2 0 0 2 2 2 2 Carbon-nitrogen hydrolase MMS1_N PF10433.9 OAP56280.1 - 2.6e-158 527.7 0.0 3.6e-158 527.2 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 OAP56280.1 - 2.5e-96 322.8 0.0 2.7e-95 319.4 0.0 2.5 3 0 0 3 3 3 1 CPSF A subunit region ANAPC4_WD40 PF12894.7 OAP56280.1 - 0.014 15.7 0.0 1.1 9.7 0.0 4.0 5 1 0 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain BBS2_N PF14781.6 OAP56280.1 - 0.036 14.0 0.1 5.8 6.9 0.0 3.5 3 1 0 3 3 3 0 Ciliary BBSome complex subunit 2, N-terminal ubiquitin PF00240.23 OAP56281.1 - 7.5e-19 67.3 0.0 1.2e-18 66.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 OAP56281.1 - 6.3e-11 42.0 0.3 6.3e-11 42.0 0.3 2.1 2 0 0 2 2 2 1 UBA/TS-N domain Rad60-SLD PF11976.8 OAP56281.1 - 4.7e-06 26.4 0.0 8e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 OAP56281.1 - 9.3e-05 22.5 0.1 0.00017 21.7 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 OAP56281.1 - 0.0015 19.0 0.0 0.0032 18.0 0.0 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain HOIP-UBA PF16678.5 OAP56281.1 - 0.018 15.1 0.0 0.034 14.1 0.0 1.4 1 0 0 1 1 1 0 HOIP UBA domain pair YukD PF08817.10 OAP56281.1 - 0.093 13.4 0.0 0.28 11.9 0.0 1.8 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD Ubiquitin_5 PF18037.1 OAP56281.1 - 0.11 12.9 0.0 0.18 12.2 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-like domain EBV-NA3 PF05009.12 OAP56281.1 - 0.14 11.6 0.8 0.25 10.8 0.1 1.7 2 0 0 2 2 2 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) GerD PF17898.1 OAP56281.1 - 4.7 7.2 8.3 27 4.8 7.9 2.3 1 1 0 1 1 1 0 Spore germination GerD central core domain EthD PF07110.11 OAP56282.1 - 0.018 16.2 0.0 0.044 14.9 0.0 1.6 1 1 0 1 1 1 0 EthD domain WD40 PF00400.32 OAP56283.1 - 1.2e-08 35.5 4.8 0.057 14.3 0.2 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat Methyltransf_16 PF10294.9 OAP56284.1 - 7.9e-21 74.6 0.0 1e-20 74.2 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 OAP56284.1 - 1.1e-06 28.6 0.0 1.5e-06 28.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 OAP56284.1 - 0.022 14.4 0.0 0.029 14.0 0.0 1.1 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_25 PF13649.6 OAP56284.1 - 0.034 14.8 0.0 0.058 14.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 OAP56284.1 - 0.16 11.5 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Pox_A12 PF04651.13 OAP56285.1 - 3.4 7.7 7.8 5.4 7.0 7.8 1.3 1 0 0 1 1 1 0 Poxvirus A12 protein Methyltransf_31 PF13847.6 OAP56286.1 - 1.2e-23 83.5 0.0 2.1e-23 82.8 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAP56286.1 - 6.6e-22 78.0 0.0 2.3e-21 76.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAP56286.1 - 6.6e-21 74.8 0.0 1.9e-20 73.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAP56286.1 - 1.8e-14 53.9 0.0 2.7e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAP56286.1 - 4.8e-14 52.9 0.0 8e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAP56286.1 - 1e-10 41.4 0.0 1.4e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 OAP56286.1 - 3.7e-08 33.1 0.0 9e-08 31.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_8 PF05148.15 OAP56286.1 - 1.9e-06 27.9 0.0 1.3e-05 25.2 0.0 2.0 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_4 PF02390.17 OAP56286.1 - 0.0006 19.3 0.0 0.002 17.6 0.0 1.8 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_2 PF00891.18 OAP56286.1 - 0.0015 17.8 0.0 0.0018 17.6 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_9 PF08003.11 OAP56286.1 - 0.0034 16.4 0.0 0.0051 15.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) PCMT PF01135.19 OAP56286.1 - 0.006 16.4 0.0 0.0088 15.8 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.19 OAP56286.1 - 0.0085 16.2 0.0 0.014 15.5 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_32 PF13679.6 OAP56286.1 - 0.011 15.7 0.0 0.022 14.7 0.0 1.4 2 0 0 2 2 2 0 Methyltransferase domain MetW PF07021.12 OAP56286.1 - 0.019 14.6 0.0 0.057 13.0 0.0 1.7 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW DUF1223 PF06764.11 OAP56287.1 - 2.3e-46 158.4 0.0 3.8e-46 157.7 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1223) ThiS PF02597.20 OAP56288.1 - 1.1e-09 38.8 0.2 0.00024 21.7 0.0 2.1 2 0 0 2 2 2 2 ThiS family UDPGP PF01704.18 OAP56289.1 - 2.1e-193 642.6 0.0 2.5e-193 642.4 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase DUF2977 PF11192.8 OAP56289.1 - 0.049 13.8 0.0 2.4 8.4 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2977) C2 PF00168.30 OAP56290.1 - 4.8e-79 261.3 0.1 5.3e-20 71.6 0.0 5.4 5 0 0 5 5 5 5 C2 domain SMP_LBD PF17047.5 OAP56290.1 - 0.00079 18.9 0.0 0.0019 17.7 0.0 1.6 1 1 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain MLVIN_C PF18697.1 OAP56290.1 - 0.14 12.3 0.2 2.3 8.4 0.0 2.7 2 0 0 2 2 2 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain ING PF12998.7 OAP56291.1 - 2.1e-17 63.6 4.3 2.1e-17 63.6 4.3 1.7 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 OAP56291.1 - 7.9e-07 28.9 10.0 1.4e-06 28.1 10.0 1.4 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 OAP56291.1 - 0.0032 17.7 2.6 0.01 16.1 2.6 1.9 1 1 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 OAP56291.1 - 0.0082 16.3 0.6 0.021 15.0 0.6 1.7 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-4CXXC_R1 PF10497.9 OAP56291.1 - 0.021 15.0 6.0 0.048 13.9 6.0 1.6 1 0 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 zf-RING_2 PF13639.6 OAP56291.1 - 1.8 9.0 6.5 3.3 8.1 6.5 1.4 1 0 0 1 1 1 0 Ring finger domain Hist_deacetyl PF00850.19 OAP56292.1 - 5.2e-80 269.2 0.0 6.9e-80 268.8 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain RNA_pol_Rpc34 PF05158.12 OAP56293.1 - 1.5e-72 244.8 0.0 2.4e-72 244.2 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit RPA_C PF08784.11 OAP56293.1 - 0.1 13.3 0.1 0.47 11.2 0.0 2.1 2 0 0 2 2 2 0 Replication protein A C terminal NAM PF02365.15 OAP56293.1 - 0.45 11.4 4.9 0.47 11.4 0.9 3.0 2 2 0 2 2 2 0 No apical meristem (NAM) protein TPR_1 PF00515.28 OAP56294.1 - 1.4e-46 154.5 20.7 1.3e-05 24.8 0.0 9.6 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_2 PF07719.17 OAP56294.1 - 1.8e-37 124.4 21.5 0.00028 20.8 0.0 9.8 9 0 0 9 9 9 9 Tetratricopeptide repeat STI1 PF17830.1 OAP56294.1 - 3.2e-37 126.2 10.1 1.8e-20 72.6 1.6 2.8 3 0 0 3 3 2 2 STI1 domain TPR_11 PF13414.6 OAP56294.1 - 5.8e-20 70.7 9.8 0.00062 19.4 0.0 7.9 5 2 2 7 7 7 4 TPR repeat TPR_8 PF13181.6 OAP56294.1 - 1.5e-15 56.0 20.0 0.041 14.1 0.0 9.4 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_19 PF14559.6 OAP56294.1 - 5.7e-13 49.2 12.4 0.025 15.1 0.1 6.3 4 1 1 6 6 6 4 Tetratricopeptide repeat TPR_9 PF13371.6 OAP56294.1 - 2.1e-12 47.0 3.2 0.00012 22.1 0.0 5.2 3 2 3 6 6 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 OAP56294.1 - 1.6e-11 44.3 15.6 2e-06 28.0 0.0 7.0 5 2 2 7 7 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 OAP56294.1 - 1.7e-11 44.5 9.4 0.00013 22.5 0.0 5.9 6 1 0 7 7 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 OAP56294.1 - 2e-11 43.7 12.5 0.72 10.8 0.1 8.8 4 3 4 9 9 9 3 Tetratricopeptide repeat TPR_17 PF13431.6 OAP56294.1 - 2.8e-10 39.8 4.0 0.038 14.4 0.1 7.3 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 OAP56294.1 - 1.7e-08 33.9 3.7 0.16 12.0 0.0 7.3 7 0 0 7 7 7 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 OAP56294.1 - 7.7e-06 25.9 4.6 0.078 13.1 0.0 5.7 5 1 1 6 6 6 1 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.6 OAP56294.1 - 2.7e-05 24.5 19.7 0.63 10.8 0.0 8.7 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_10 PF13374.6 OAP56294.1 - 9.5e-05 22.1 6.2 0.45 10.5 0.0 6.6 6 1 1 7 7 7 1 Tetratricopeptide repeat ANAPC3 PF12895.7 OAP56294.1 - 0.001 19.3 9.8 0.089 13.0 0.2 4.2 3 1 1 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 Alkyl_sulf_dimr PF14863.6 OAP56294.1 - 0.89 10.0 8.9 11 6.4 0.9 3.9 4 0 0 4 4 3 0 Alkyl sulfatase dimerisation TPR_20 PF14561.6 OAP56294.1 - 6.4 7.2 10.5 1.8 8.9 0.1 4.6 3 2 2 5 5 5 0 Tetratricopeptide repeat Trypan_PARP PF05887.11 OAP56294.1 - 6.5 6.7 20.8 3.3 7.7 17.3 2.3 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) DUF627 PF04781.12 OAP56294.1 - 8.9 6.4 7.4 62 3.7 0.3 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF627) Na_H_Exchanger PF00999.21 OAP56295.1 - 1.7e-55 188.3 55.1 2.6e-55 187.8 55.1 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Inhibitor_G39P PF11417.8 OAP56296.1 - 0.13 12.8 0.0 0.24 11.9 0.0 1.4 1 0 0 1 1 1 0 Loader and inhibitor of phage G40P UBX PF00789.20 OAP56299.1 - 2.4e-11 43.7 0.0 6.8e-11 42.2 0.0 1.8 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.6 OAP56299.1 - 7.4e-11 41.7 0.0 1.9e-10 40.4 0.0 1.7 1 0 0 1 1 1 1 UBA-like domain DUF1682 PF07946.14 OAP56299.1 - 0.035 13.3 8.2 0.065 12.4 8.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Exonuc_VII_L PF02601.15 OAP56299.1 - 0.36 10.3 8.7 0.56 9.7 8.7 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Presenilin PF01080.17 OAP56299.1 - 3 6.5 6.1 12 4.5 6.3 1.8 2 0 0 2 2 2 0 Presenilin Pan3_PK PF18101.1 OAP56300.1 - 7.7e-64 213.8 0.8 1.1e-63 213.3 0.8 1.3 1 0 0 1 1 1 1 Pan3 Pseudokinase domain Pkinase PF00069.25 OAP56300.1 - 1.5e-07 31.1 0.0 2.5e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP56300.1 - 0.0056 16.0 0.0 0.009 15.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Mucin PF01456.17 OAP56300.1 - 0.045 13.7 13.2 0.079 12.9 13.2 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein PAM2 PF07145.15 OAP56300.1 - 6.5 6.7 6.7 2.1 8.2 0.2 2.8 3 0 0 3 3 3 0 Ataxin-2 C-terminal region LSM PF01423.22 OAP56301.1 - 9.1e-22 76.5 0.4 1.1e-21 76.2 0.4 1.1 1 0 0 1 1 1 1 LSM domain DUF150_C PF17384.2 OAP56301.1 - 0.055 13.6 0.1 0.095 12.8 0.1 1.4 1 0 0 1 1 1 0 RimP C-terminal SH3 domain FoP_duplication PF13865.6 OAP56301.1 - 0.12 12.9 11.5 0.19 12.3 11.5 1.3 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 RhlB PF12300.8 OAP56301.1 - 3.9 7.6 11.7 5.7 7.0 11.7 1.2 1 0 0 1 1 1 0 ATP-dependent RNA helicase RhlB Zn_clus PF00172.18 OAP56302.1 - 0.029 14.5 9.5 0.062 13.4 9.5 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Dioxygenase_C PF00775.21 OAP56303.1 - 5.4e-43 146.5 0.0 7.6e-43 146.0 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 OAP56303.1 - 4.6e-27 93.7 0.0 8.8e-27 92.8 0.0 1.5 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 OAP56303.1 - 0.11 12.8 0.0 0.65 10.3 0.0 2.2 1 1 0 1 1 1 0 Carboxypeptidase regulatory-like domain TauD PF02668.16 OAP56304.1 - 5.4e-33 114.9 0.0 7e-33 114.6 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DAG1 PF05454.11 OAP56304.1 - 0.13 11.6 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) MFS_1 PF07690.16 OAP56305.1 - 1.8e-31 109.4 32.0 1.8e-31 109.4 32.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAP56305.1 - 2.4e-10 39.9 20.6 5.8e-10 38.6 20.6 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter Xan_ur_permease PF00860.20 OAP56306.1 - 2.1e-63 214.3 30.5 3.2e-62 210.5 30.5 2.0 1 1 0 1 1 1 1 Permease family Sugar_tr PF00083.24 OAP56307.1 - 2.1e-85 287.3 12.3 2.4e-85 287.1 12.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP56307.1 - 4.5e-28 98.2 16.7 6.5e-28 97.7 16.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 OAP56307.1 - 2.8e-05 22.9 15.5 0.00031 19.4 0.5 2.7 3 0 0 3 3 3 2 MFS/sugar transport protein TRI12 PF06609.13 OAP56307.1 - 5.6e-05 21.8 0.8 5.6e-05 21.8 0.8 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) PTR2 PF00854.21 OAP56307.1 - 0.041 12.7 9.1 0.42 9.4 0.8 2.5 2 1 0 2 2 2 0 POT family DUF1682 PF07946.14 OAP56309.1 - 1.2e-107 359.9 0.9 1.4e-107 359.7 0.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) Peptidase_M20 PF01546.28 OAP56311.1 - 3.4e-25 89.0 0.0 2.6e-20 73.0 0.0 2.5 2 0 0 2 2 2 2 Peptidase family M20/M25/M40 WD40 PF00400.32 OAP56311.1 - 3.4e-10 40.3 1.8 0.55 11.2 0.0 6.6 6 0 0 6 6 6 3 WD domain, G-beta repeat M20_dimer PF07687.14 OAP56311.1 - 1e-05 25.4 0.0 2.7e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain ANAPC4_WD40 PF12894.7 OAP56311.1 - 1.3e-05 25.4 0.1 0.045 14.0 0.0 3.3 2 1 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 OAP56311.1 - 0.0026 18.2 0.0 0.36 11.4 0.0 3.3 3 0 0 3 3 3 1 PQQ-like domain WD40_like PF17005.5 OAP56311.1 - 0.032 13.5 0.0 3.1 7.0 0.0 2.3 2 0 0 2 2 2 0 WD40-like domain Asparaginase_2 PF01112.18 OAP56312.1 - 3.4e-54 183.9 0.0 2.5e-50 171.2 0.0 2.5 3 0 0 3 3 3 2 Asparaginase Transket_pyr PF02779.24 OAP56313.1 - 1.1e-42 145.7 0.0 1.8e-42 145.0 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 OAP56313.1 - 8.4e-32 109.7 0.0 1.8e-31 108.6 0.0 1.6 2 0 0 2 2 2 1 Transketolase, C-terminal domain HTH_Tnp_Tc5 PF03221.16 OAP56314.1 - 0.00063 19.7 0.0 0.0014 18.6 0.0 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_1 PF03184.19 OAP56314.1 - 0.013 15.1 0.0 0.52 10.0 0.0 2.6 3 0 0 3 3 3 0 DDE superfamily endonuclease Helo_like_N PF17111.5 OAP56315.1 - 3.9e-12 46.0 0.1 5e-12 45.6 0.1 1.1 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins NPV_P10 PF05531.12 OAP56315.1 - 0.0014 19.0 6.0 0.74 10.3 0.1 3.4 3 1 0 3 3 3 2 Nucleopolyhedrovirus P10 protein Phage_HK97_TLTM PF06120.11 OAP56315.1 - 0.0016 17.7 0.6 0.0021 17.3 0.6 1.2 1 1 0 1 1 1 1 Tail length tape measure protein Baculo_PEP_C PF04513.12 OAP56315.1 - 0.0045 17.0 2.9 0.64 10.1 0.6 2.5 2 1 0 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_13 PF13166.6 OAP56315.1 - 0.0098 14.6 0.4 0.013 14.2 0.4 1.1 1 0 0 1 1 1 1 AAA domain Rogdi_lz PF10259.9 OAP56315.1 - 0.01 15.3 0.1 0.014 14.9 0.1 1.3 1 0 0 1 1 1 0 Rogdi leucine zipper containing protein HeLo PF14479.6 OAP56315.1 - 0.012 15.4 0.7 0.015 15.1 0.7 1.1 1 0 0 1 1 1 0 Prion-inhibition and propagation SesA PF17107.5 OAP56315.1 - 0.017 15.3 1.7 0.093 12.9 0.1 2.0 1 1 1 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases HIP1_clath_bdg PF16515.5 OAP56315.1 - 0.039 14.6 0.4 13 6.4 0.1 2.3 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 PIN_8 PF18476.1 OAP56315.1 - 0.084 12.7 2.6 0.55 10.1 2.9 1.8 1 1 0 1 1 1 0 PIN like domain DUF848 PF05852.11 OAP56315.1 - 0.14 12.3 3.9 0.29 11.2 3.4 1.8 1 1 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) SlyX PF04102.12 OAP56315.1 - 0.81 10.3 5.7 27 5.5 0.1 3.4 2 2 1 3 3 3 0 SlyX HSP9_HSP12 PF04119.12 OAP56315.1 - 1.1 9.7 3.4 1.2 9.5 0.4 2.2 2 0 0 2 2 2 0 Heat shock protein 9/12 Ank_4 PF13637.6 OAP56316.1 - 8.8e-24 83.6 0.3 2.6e-10 40.6 0.0 3.4 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 OAP56316.1 - 2.8e-23 82.3 0.7 1.4e-08 35.1 0.0 2.8 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 OAP56316.1 - 2.8e-15 56.0 0.6 0.00095 19.5 0.0 4.8 4 1 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 OAP56316.1 - 1.6e-09 37.2 0.0 0.16 12.6 0.0 3.8 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 OAP56316.1 - 1.8e-05 24.9 0.3 0.29 11.5 0.1 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Staphostatin_A PF09022.10 OAP56317.1 - 0.026 14.4 0.0 0.043 13.7 0.0 1.3 1 0 0 1 1 1 0 Staphostatin A HET PF06985.11 OAP56319.1 - 2.7e-20 73.2 0.3 6.2e-20 72.0 0.3 1.7 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Pkinase PF00069.25 OAP56321.1 - 3.3e-13 49.6 0.2 5.2e-13 49.0 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP56321.1 - 1.6e-06 27.6 0.1 4.5e-06 26.1 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase DUF21 PF01595.20 OAP56322.1 - 1.9e-33 115.6 0.0 3.1e-33 114.9 0.0 1.2 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 OAP56322.1 - 3.5e-06 27.4 0.5 0.014 15.8 0.0 3.0 2 0 0 2 2 2 2 CBS domain DUF3255 PF11631.8 OAP56322.1 - 0.17 11.7 0.1 0.32 10.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3255) Glyco_hydro_15 PF00723.21 OAP56324.1 - 6.9e-51 173.4 0.0 2.6e-47 161.6 0.0 2.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 15 TPT PF03151.16 OAP56325.1 - 3.4e-21 75.9 22.9 4.4e-21 75.5 22.9 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 OAP56325.1 - 4.1e-06 27.0 36.9 0.0073 16.5 17.4 2.4 2 0 0 2 2 2 2 EamA-like transporter family DUF2681 PF10883.8 OAP56325.1 - 0.073 13.5 0.0 0.22 11.9 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Plasmodium_Vir PF05795.11 OAP56325.1 - 0.1 12.0 0.1 0.71 9.2 0.0 2.0 2 0 0 2 2 2 0 Plasmodium vivax Vir protein PUNUT PF16913.5 OAP56325.1 - 0.12 11.6 23.3 0.27 10.4 21.9 2.1 1 1 1 2 2 2 0 Purine nucleobase transmembrane transport UAA PF08449.11 OAP56325.1 - 0.15 11.2 30.8 0.095 11.9 24.7 2.0 1 1 0 2 2 2 0 UAA transporter family DUF3949 PF13133.6 OAP56325.1 - 7.7 7.1 5.4 45 4.6 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3949) adh_short PF00106.25 OAP56326.1 - 4.5e-33 114.4 0.0 6.9e-33 113.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP56326.1 - 4.8e-29 101.6 0.0 7.5e-29 100.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase HET PF06985.11 OAP56326.1 - 3.9e-23 82.4 0.0 7.2e-23 81.6 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) KR PF08659.10 OAP56326.1 - 0.00013 21.9 0.0 0.00084 19.3 0.0 2.1 1 1 0 1 1 1 1 KR domain Lactamase_B PF00753.27 OAP56327.1 - 1.6e-16 60.9 0.2 3.7e-16 59.7 0.2 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OAP56327.1 - 0.00041 19.9 0.0 0.00094 18.7 0.0 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 OAP56327.1 - 0.036 14.0 0.1 0.2 11.6 0.0 2.0 2 0 0 2 2 2 0 Beta-lactamase superfamily domain AD PF09793.9 OAP56330.1 - 1e-18 67.2 0.0 1.6e-18 66.6 0.0 1.3 1 0 0 1 1 1 1 Anticodon-binding domain Parecho_VpG PF06344.11 OAP56330.1 - 0.28 11.9 1.6 31 5.5 0.1 3.4 3 0 0 3 3 3 0 Parechovirus Genome-linked protein 6PGD PF00393.19 OAP56331.1 - 1.2e-127 425.3 0.0 1.5e-127 424.9 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 OAP56331.1 - 5e-50 169.8 0.0 7.4e-50 169.2 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 OAP56331.1 - 0.033 14.4 0.4 0.093 13.0 0.0 2.0 2 0 0 2 2 2 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase RRM_1 PF00076.22 OAP56332.1 - 2e-18 66.0 0.0 3.1e-18 65.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.11 OAP56332.1 - 0.12 12.0 0.1 0.23 11.1 0.1 1.3 1 0 0 1 1 1 0 Ribonuclease B OB domain MbeD_MobD PF04899.12 OAP56332.1 - 0.22 11.6 0.4 0.41 10.8 0.4 1.3 1 0 0 1 1 1 0 MbeD/MobD like Peptidase_C2 PF00648.21 OAP56333.1 - 2.7e-62 210.5 0.4 8.4e-61 205.6 0.4 2.3 1 1 0 1 1 1 1 Calpain family cysteine protease Porin_1 PF00267.21 OAP56333.1 - 0.13 11.6 0.2 0.21 11.0 0.2 1.2 1 0 0 1 1 1 0 Gram-negative porin DDRGK PF09756.9 OAP56333.1 - 8 6.0 27.1 15 5.2 27.1 1.4 1 0 0 1 1 1 0 DDRGK domain Sugar_tr PF00083.24 OAP56334.1 - 8.2e-78 262.3 24.3 9.6e-78 262.0 24.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP56334.1 - 7.2e-16 58.1 32.0 7.2e-16 58.1 32.0 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF3906 PF13046.6 OAP56334.1 - 0.1 12.7 0.1 0.21 11.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3906) tRNA-synt_1b PF00579.25 OAP56335.1 - 3.4e-64 217.0 0.0 4.3e-64 216.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Pkinase PF00069.25 OAP56336.1 - 1.5e-70 237.6 0.0 2e-70 237.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP56336.1 - 1.6e-30 106.3 0.0 2.1e-30 105.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAP56336.1 - 0.00015 21.2 0.0 0.00028 20.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OAP56336.1 - 0.0013 17.7 0.0 0.014 14.3 0.0 1.9 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 OAP56336.1 - 0.0055 16.7 0.0 0.0077 16.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 OAP56336.1 - 0.012 14.7 0.0 0.018 14.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 EPSP_synthase PF00275.20 OAP56337.1 - 0.035 12.8 0.1 0.046 12.4 0.1 1.1 1 0 0 1 1 1 0 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) HisKA_7TM PF16927.5 OAP56337.1 - 0.053 13.6 10.3 0.95 9.4 0.5 2.5 2 1 0 2 2 2 0 N-terminal 7TM region of histidine kinase DUF4271 PF14093.6 OAP56337.1 - 0.073 13.0 7.7 0.75 9.7 0.1 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4271) DUF3180 PF11377.8 OAP56337.1 - 0.08 13.1 8.8 0.29 11.3 2.0 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3180) DUF5316 PF17247.2 OAP56337.1 - 0.18 11.8 2.4 3 7.9 0.0 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF5316) MIG-14_Wnt-bd PF06664.12 OAP56337.1 - 2.5 7.2 10.0 1 8.5 3.0 2.3 1 1 0 2 2 2 0 Wnt-binding factor required for Wnt secretion Peptidase_S28 PF05577.12 OAP56338.1 - 6.1e-39 134.0 0.4 1.3e-37 129.7 0.4 2.0 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S9 PF00326.21 OAP56338.1 - 9.5e-11 41.6 0.1 2e-08 34.0 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 OAP56338.1 - 0.00058 19.2 0.0 0.00092 18.5 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OAP56338.1 - 0.00097 19.8 0.0 0.34 11.5 0.0 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase family DUF2920 PF11144.8 OAP56338.1 - 0.017 14.3 0.0 0.025 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) Abhydrolase_1 PF00561.20 OAP56338.1 - 0.084 12.5 0.0 0.19 11.4 0.0 1.6 2 0 0 2 2 2 0 alpha/beta hydrolase fold PTR2 PF00854.21 OAP56339.1 - 1.3e-83 281.0 7.7 1.7e-83 280.7 7.7 1.1 1 0 0 1 1 1 1 POT family MFS_1 PF07690.16 OAP56339.1 - 1.5e-05 24.1 29.7 1.9e-05 23.7 26.5 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily HSD3 PF15244.6 OAP56340.1 - 3.7 7.0 5.2 6.2 6.2 5.2 1.3 1 0 0 1 1 1 0 Spermatogenesis-associated protein 7, or HSD3 Isochorismatase PF00857.20 OAP56341.1 - 3.6e-20 72.9 0.0 5.1e-20 72.4 0.0 1.2 1 0 0 1 1 1 1 Isochorismatase family AMPK1_CBM PF16561.5 OAP56342.1 - 7.7e-09 35.7 0.4 2.9e-07 30.6 0.4 2.2 1 1 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase DUF4493 PF14900.6 OAP56342.1 - 0.0094 15.8 0.1 0.013 15.4 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4493) NOC3p PF07540.11 OAP56343.1 - 1.2e-27 96.2 0.8 5e-27 94.2 0.0 2.5 2 0 0 2 2 2 1 Nucleolar complex-associated protein CBF PF03914.17 OAP56343.1 - 3.3e-17 63.1 0.1 9.6e-17 61.5 0.0 1.9 2 0 0 2 2 2 1 CBF/Mak21 family Bud13 PF09736.9 OAP56343.1 - 5.1 7.5 9.4 24 5.3 0.7 2.8 2 0 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex UPF0113_N PF17833.1 OAP56344.1 - 1e-26 93.3 0.0 1.4e-26 92.9 0.0 1.2 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 OAP56344.1 - 2.8e-22 78.8 0.0 4.1e-22 78.2 0.0 1.3 1 0 0 1 1 1 1 UPF0113 PUA domain PUA PF01472.20 OAP56344.1 - 0.047 13.7 0.0 0.082 12.9 0.0 1.4 1 0 0 1 1 1 0 PUA domain ApoO PF09769.9 OAP56345.1 - 3.2e-41 140.3 0.9 3.3e-40 137.0 0.0 2.1 2 0 0 2 2 2 1 Apolipoprotein O NODP PF07684.12 OAP56345.1 - 0.24 11.6 0.3 0.45 10.7 0.3 1.5 1 0 0 1 1 1 0 NOTCH protein Glyco_hydro_43 PF04616.14 OAP56346.1 - 3e-70 236.8 0.2 3.9e-70 236.4 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 OAP56346.1 - 1.4e-09 37.9 0.0 3e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain FMO-like PF00743.19 OAP56347.1 - 6.8e-23 80.9 0.0 1.2e-12 47.0 0.0 3.0 3 0 0 3 3 3 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OAP56347.1 - 8.7e-10 38.3 0.2 9.3e-06 25.1 0.0 3.0 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAP56347.1 - 7.5e-08 32.0 0.0 0.006 15.9 0.0 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAP56347.1 - 5.5e-07 29.7 0.0 1.8e-06 28.1 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 OAP56347.1 - 3.6e-06 27.1 0.1 0.00015 21.8 0.1 3.0 2 1 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.24 OAP56347.1 - 4.1e-06 26.6 0.8 0.011 15.3 0.6 2.7 3 0 0 3 3 3 2 FAD dependent oxidoreductase K_oxygenase PF13434.6 OAP56347.1 - 0.00034 19.9 1.1 0.28 10.3 0.0 3.7 3 1 1 4 4 4 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 OAP56347.1 - 0.0032 16.7 0.1 0.014 14.6 0.1 1.9 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 OAP56347.1 - 0.063 12.3 0.8 0.11 11.5 0.8 1.4 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 OAP56347.1 - 0.069 11.8 0.8 0.11 11.1 0.8 1.3 1 0 0 1 1 1 0 HI0933-like protein Shikimate_DH PF01488.20 OAP56347.1 - 0.097 12.7 0.0 7 6.7 0.0 2.8 4 0 0 4 4 4 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 OAP56347.1 - 0.12 12.9 0.1 0.76 10.4 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Glu_dehyd_C PF16912.5 OAP56347.1 - 0.15 11.6 0.0 1.4 8.4 0.0 2.2 2 1 0 2 2 2 0 Glucose dehydrogenase C-terminus GIDA PF01134.22 OAP56347.1 - 0.25 10.4 1.3 0.35 9.9 1.3 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A LapA_dom PF06305.11 OAP56348.1 - 0.52 10.2 0.1 0.52 10.2 0.1 3.6 5 0 0 5 5 5 0 Lipopolysaccharide assembly protein A domain DUF2721 PF11026.8 OAP56348.1 - 2.8 7.8 6.8 0.99 9.3 0.2 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2721) Peptidase_M3 PF01432.20 OAP56349.1 - 1.5e-114 383.8 0.0 2.2e-114 383.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 O-FucT PF10250.9 OAP56349.1 - 0.0098 15.6 0.4 0.017 14.8 0.4 1.3 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Fungal_trans PF04082.18 OAP56350.1 - 9.1e-07 28.2 0.0 1.5e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Methyltransf_11 PF08241.12 OAP56351.1 - 2.4e-16 60.2 0.0 4.3e-16 59.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAP56351.1 - 1.4e-14 54.6 0.0 2.7e-14 53.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAP56351.1 - 5.1e-11 43.2 0.0 9.5e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAP56351.1 - 2.4e-08 33.9 0.0 3.9e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAP56351.1 - 4.7e-07 29.8 0.0 1.5e-06 28.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAP56351.1 - 0.00059 19.2 0.0 0.001 18.4 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Zn_clus PF00172.18 OAP56352.1 - 1e-07 31.9 11.3 1.8e-07 31.2 11.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 OAP56352.1 - 3.5e-06 26.1 0.0 5.5e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Intg_mem_TP0381 PF09529.10 OAP56352.1 - 0.12 11.9 0.2 3.7 7.0 0.0 2.2 2 0 0 2 2 2 0 Integral membrane protein (intg_mem_TP0381) Thioredoxin PF00085.20 OAP56354.1 - 2.5e-61 204.1 0.4 7.8e-30 102.9 0.0 3.9 4 0 0 4 4 4 3 Thioredoxin Thioredoxin_6 PF13848.6 OAP56354.1 - 3e-49 167.5 0.0 1e-35 123.3 0.0 3.3 2 1 1 3 3 3 3 Thioredoxin-like domain Calsequestrin PF01216.17 OAP56354.1 - 2.1e-08 33.6 0.3 3.8e-08 32.8 0.1 1.5 1 1 0 1 1 1 1 Calsequestrin Thioredoxin_8 PF13905.6 OAP56354.1 - 5.4e-08 33.1 0.0 0.13 12.6 0.0 4.8 4 1 1 5 5 5 2 Thioredoxin-like AhpC-TSA PF00578.21 OAP56354.1 - 1.2e-07 31.7 0.8 0.047 13.6 0.0 4.2 4 0 0 4 4 4 2 AhpC/TSA family Redoxin PF08534.10 OAP56354.1 - 5.1e-07 29.5 3.0 0.067 12.9 0.0 4.0 3 1 1 4 4 4 3 Redoxin Thioredoxin_7 PF13899.6 OAP56354.1 - 8.2e-07 29.1 0.2 0.038 14.2 0.0 3.3 4 0 0 4 4 4 2 Thioredoxin-like Thioredoxin_2 PF13098.6 OAP56354.1 - 2e-06 28.2 0.2 0.024 15.1 0.0 3.1 2 1 0 2 2 2 2 Thioredoxin-like domain OST3_OST6 PF04756.13 OAP56354.1 - 0.00035 20.0 0.0 1.4 8.2 0.0 3.3 2 1 0 3 3 3 2 OST3 / OST6 family, transporter family Thioredoxin_4 PF13462.6 OAP56354.1 - 0.0039 17.4 0.7 0.78 9.9 0.0 3.6 3 0 0 3 3 3 1 Thioredoxin NCBP3 PF10309.9 OAP56354.1 - 0.096 12.5 0.0 20 5.1 0.0 3.2 3 0 0 3 3 3 0 Nuclear cap-binding protein subunit 3 Thioredoxin_3 PF13192.6 OAP56354.1 - 0.17 11.9 0.3 2 8.5 0.1 2.6 3 0 0 3 3 3 0 Thioredoxin domain ATG22 PF11700.8 OAP56355.1 - 1.2e-205 683.7 6.5 1.4e-205 683.5 6.5 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 OAP56355.1 - 6.5e-07 28.6 52.2 1.1e-05 24.5 23.5 3.3 2 1 1 3 3 3 3 Major Facilitator Superfamily Med14 PF08638.11 OAP56356.1 - 6.6e-58 195.3 0.0 1.3e-57 194.3 0.0 1.5 1 0 0 1 1 1 1 Mediator complex subunit MED14 UDG PF03167.19 OAP56357.1 - 3.7e-21 75.7 0.0 7.2e-21 74.8 0.0 1.4 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Zn_clus PF00172.18 OAP56358.1 - 4.8e-10 39.4 9.0 9.9e-10 38.4 9.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TMEM108 PF15759.5 OAP56358.1 - 0.028 13.5 0.4 0.038 13.0 0.4 1.1 1 0 0 1 1 1 0 TMEM108 family Glyco_hydro_20 PF00728.22 OAP56359.1 - 9.3e-104 347.6 1.3 1.3e-103 347.2 1.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 OAP56359.1 - 7.6e-23 81.7 0.2 3.1e-22 79.7 0.1 2.0 2 0 0 2 2 2 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 OAP56359.1 - 0.0037 18.0 0.1 0.0085 16.9 0.1 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 MmgE_PrpD PF03972.14 OAP56360.1 - 9e-115 383.7 0.0 1.1e-114 383.4 0.0 1.1 1 0 0 1 1 1 1 MmgE/PrpD family Abhydrolase_1 PF00561.20 OAP56362.1 - 4.7e-13 49.4 0.1 7.1e-13 48.8 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAP56362.1 - 4.9e-13 50.2 1.6 9.1e-13 49.3 1.6 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAP56362.1 - 6.6e-08 32.1 0.0 1.1e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 GMC_oxred_N PF00732.19 OAP56363.1 - 1.8e-54 185.1 0.0 2.4e-54 184.7 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAP56363.1 - 1.4e-21 77.5 0.0 2.7e-21 76.6 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 OAP56363.1 - 1.2e-08 34.5 4.0 0.00062 19.0 1.8 2.2 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.17 OAP56363.1 - 6.2e-05 22.4 1.1 0.0011 18.3 0.2 2.1 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.12 OAP56363.1 - 0.00027 20.1 0.3 0.00041 19.5 0.3 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 OAP56363.1 - 0.00038 20.1 0.2 0.0096 15.5 0.3 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAP56363.1 - 0.0014 18.8 1.7 0.0025 18.0 0.7 2.0 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAP56363.1 - 0.006 15.9 0.2 0.017 14.3 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAP56363.1 - 0.0099 14.6 0.2 0.016 14.0 0.2 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 OAP56363.1 - 0.014 15.9 2.0 1 10.0 0.3 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAP56363.1 - 0.017 14.4 2.3 1.4 8.1 1.3 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OAP56363.1 - 0.034 13.2 0.6 4.7 6.2 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Trp_halogenase PF04820.14 OAP56363.1 - 0.087 11.7 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Caleosin PF05042.13 OAP56364.1 - 6.1e-76 254.1 0.1 7.6e-76 253.8 0.1 1.1 1 0 0 1 1 1 1 Caleosin related protein EF-hand_6 PF13405.6 OAP56364.1 - 3.5e-06 26.5 1.3 0.0037 17.1 0.0 3.4 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.32 OAP56364.1 - 7.8e-05 22.0 1.7 0.0045 16.4 0.0 3.1 3 0 0 3 3 3 1 EF hand EF-hand_7 PF13499.6 OAP56364.1 - 0.0025 18.3 0.3 0.22 12.0 0.0 2.9 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_8 PF13833.6 OAP56364.1 - 0.083 12.7 0.1 2 8.3 0.0 2.7 3 0 0 3 3 3 0 EF-hand domain pair EF-hand_5 PF13202.6 OAP56364.1 - 0.16 11.5 6.3 1 8.9 0.1 3.3 3 0 0 3 3 3 0 EF hand Aminotran_1_2 PF00155.21 OAP56365.1 - 2.5e-35 122.3 0.0 3.3e-35 121.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_3 PF00202.21 OAP56365.1 - 0.084 11.5 0.0 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-III Sugar_tr PF00083.24 OAP56366.1 - 1.7e-74 251.4 19.9 2e-74 251.1 19.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP56366.1 - 5.8e-18 64.9 42.7 3.8e-15 55.7 27.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2070 PF09843.9 OAP56366.1 - 0.018 13.4 1.2 0.032 12.5 1.2 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Cyclase PF04199.13 OAP56367.1 - 2.8e-12 47.1 0.0 3.7e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase Fungal_trans PF04082.18 OAP56368.1 - 1.2e-14 54.1 0.1 1.9e-14 53.3 0.1 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Mif2_N PF15624.6 OAP56368.1 - 0.072 13.8 1.2 4.1 8.1 0.2 2.4 2 0 0 2 2 2 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Sox17_18_mid PF12067.8 OAP56368.1 - 0.28 11.3 2.5 0.33 11.0 0.8 2.0 2 0 0 2 2 2 0 Sox 17/18 central domain FMN_dh PF01070.18 OAP56369.1 - 2.2e-109 365.7 0.0 2.6e-109 365.4 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 OAP56369.1 - 2.1e-19 69.5 0.0 8.3e-19 67.5 0.0 2.0 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 OAP56369.1 - 0.00011 21.4 0.1 0.00025 20.3 0.0 1.5 2 0 0 2 2 2 1 Conserved region in glutamate synthase NMO PF03060.15 OAP56369.1 - 0.00079 18.9 0.3 0.0012 18.3 0.3 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase ThiG PF05690.14 OAP56369.1 - 0.0011 18.3 0.0 0.043 13.1 0.0 2.5 2 0 0 2 2 2 1 Thiazole biosynthesis protein ThiG IMPDH PF00478.25 OAP56369.1 - 0.0038 16.3 0.3 0.007 15.4 0.0 1.5 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain FAD_binding_3 PF01494.19 OAP56370.1 - 1.4e-47 162.6 0.0 2.4e-47 161.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 OAP56370.1 - 0.0011 19.2 0.1 0.0067 16.6 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAP56370.1 - 0.0018 17.9 0.2 0.66 9.5 0.1 2.3 1 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAP56370.1 - 0.0038 16.5 0.0 0.0066 15.7 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAP56370.1 - 0.015 15.9 0.0 0.36 11.4 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 OAP56370.1 - 0.022 14.4 0.0 0.039 13.6 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Lycopene_cycl PF05834.12 OAP56370.1 - 0.045 12.8 0.1 0.32 10.0 0.0 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein HI0933_like PF03486.14 OAP56370.1 - 0.049 12.3 0.1 0.11 11.1 0.0 1.5 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_3 PF13738.6 OAP56370.1 - 0.066 12.5 0.1 0.13 11.5 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAP56370.1 - 0.081 12.1 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Thi4 family SE PF08491.10 OAP56370.1 - 0.089 11.8 0.0 4.1 6.4 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase NAD_binding_9 PF13454.6 OAP56370.1 - 0.11 12.5 0.3 1.3 9.0 0.2 2.7 2 1 1 3 3 3 0 FAD-NAD(P)-binding Sugar_tr PF00083.24 OAP56371.1 - 2.5e-82 277.1 17.5 3.2e-82 276.8 17.5 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP56371.1 - 1.4e-31 109.7 30.7 3e-31 108.7 30.6 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Folate_carrier PF01770.18 OAP56371.1 - 3.1e-05 22.9 0.2 4.6e-05 22.3 0.2 1.2 1 0 0 1 1 1 1 Reduced folate carrier TRI12 PF06609.13 OAP56371.1 - 0.00024 19.7 4.8 0.00024 19.7 4.8 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Peptidase_S9 PF00326.21 OAP56372.1 - 0.0038 16.7 0.0 0.011 15.2 0.0 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family BAAT_C PF08840.11 OAP56372.1 - 0.016 15.2 0.0 0.021 14.7 0.0 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.18 OAP56372.1 - 0.038 13.5 0.1 0.056 13.0 0.1 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family Carboxyl_trans PF01039.22 OAP56373.1 - 9.2e-57 192.8 0.0 1.3e-47 162.5 0.0 2.6 1 1 1 2 2 2 2 Carboxyl transferase domain DUF5427 PF10310.9 OAP56373.1 - 0.1 11.6 0.1 0.13 11.2 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) DUF2982 PF11201.8 OAP56374.1 - 0.031 13.8 0.1 0.045 13.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2982) adh_short PF00106.25 OAP56375.1 - 1.2e-32 112.9 0.0 2.9e-32 111.7 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP56375.1 - 2e-24 86.5 0.0 3.2e-24 85.8 0.0 1.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP56375.1 - 3.3e-11 43.4 0.0 4.1e-11 43.1 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAP56375.1 - 2.1e-05 24.1 0.0 2.6e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 OAP56375.1 - 0.00025 21.0 0.0 0.00034 20.5 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 OAP56375.1 - 0.0022 18.2 0.0 0.0038 17.5 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Polysacc_synt_2 PF02719.15 OAP56375.1 - 0.015 14.5 0.0 0.019 14.1 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein YihI PF04220.12 OAP56375.1 - 0.098 12.4 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Der GTPase activator (YihI) Aminotran_1_2 PF00155.21 OAP56376.1 - 1.2e-39 136.6 0.0 1.5e-39 136.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 OAP56376.1 - 1.1e-07 30.7 0.0 1.6e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 OAP56376.1 - 8.1e-06 25.0 0.0 4.3e-05 22.7 0.0 2.0 2 1 0 2 2 2 1 Aminotransferase class-V Alliinase_C PF04864.13 OAP56376.1 - 0.0034 16.3 0.0 0.014 14.3 0.0 1.9 2 0 0 2 2 2 1 Allinase Beta_elim_lyase PF01212.21 OAP56376.1 - 0.085 12.1 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase Fungal_trans PF04082.18 OAP56377.1 - 1.4e-16 60.3 0.4 3.8e-16 58.9 0.1 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Amidohydro_1 PF01979.20 OAP56378.1 - 4.1e-48 164.5 0.0 4.8e-48 164.2 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 OAP56378.1 - 1.1e-20 74.5 0.0 9.2e-14 51.8 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family DUF3868 PF12984.7 OAP56378.1 - 0.19 11.6 0.0 0.37 10.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3868) MFS_1 PF07690.16 OAP56379.1 - 1.8e-31 109.4 30.9 1.8e-31 109.4 30.9 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Glyco_hydro_43 PF04616.14 OAP56380.1 - 7.5e-15 55.0 0.1 2e-14 53.6 0.1 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 NACHT PF05729.12 OAP56381.1 - 2.7e-10 40.4 0.0 7.4e-10 39.0 0.0 1.8 1 0 0 1 1 1 1 NACHT domain zf-C2H2_4 PF13894.6 OAP56381.1 - 2.6e-07 30.9 7.7 0.13 13.1 0.1 4.3 3 0 0 3 3 3 2 C2H2-type zinc finger AAA_22 PF13401.6 OAP56381.1 - 2e-06 28.1 0.1 0.00019 21.7 0.0 3.6 3 1 0 3 3 3 1 AAA domain zf-C2H2 PF00096.26 OAP56381.1 - 8.5e-06 25.9 18.2 0.065 13.7 3.1 4.9 5 0 0 5 5 3 3 Zinc finger, C2H2 type AAA_16 PF13191.6 OAP56381.1 - 5.8e-05 23.5 0.2 0.001 19.5 0.0 3.3 2 1 1 3 3 3 1 AAA ATPase domain AAA PF00004.29 OAP56381.1 - 0.0011 19.4 0.0 0.015 15.7 0.0 2.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 OAP56381.1 - 0.0012 18.1 0.1 0.01 15.1 0.0 2.5 3 0 0 3 3 3 1 NB-ARC domain zf-H2C2_2 PF13465.6 OAP56381.1 - 0.0012 19.1 0.3 0.0012 19.1 0.3 5.5 7 1 0 7 7 6 1 Zinc-finger double domain DUF2075 PF09848.9 OAP56381.1 - 0.0027 17.0 0.0 0.0068 15.7 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) KAP_NTPase PF07693.14 OAP56381.1 - 0.0036 16.6 0.4 0.017 14.4 0.0 2.2 3 0 0 3 3 3 1 KAP family P-loop domain AAA_14 PF13173.6 OAP56381.1 - 0.0082 16.2 0.1 0.87 9.6 0.0 3.6 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 OAP56381.1 - 0.01 16.4 0.0 0.43 11.1 0.0 3.2 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 OAP56381.1 - 0.021 15.2 0.0 0.11 12.9 0.0 2.2 2 0 0 2 2 2 0 RNA helicase Viral_helicase1 PF01443.18 OAP56381.1 - 0.03 14.1 0.3 6.7 6.4 0.0 2.6 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Goodbye PF17109.5 OAP56381.1 - 0.055 13.9 0.0 0.22 12.0 0.0 2.1 1 0 0 1 1 1 0 fungal STAND N-terminal Goodbye domain Zn_ribbon_recom PF13408.6 OAP56381.1 - 0.4 11.2 7.2 1.4 9.5 7.2 2.0 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain Ribosomal_L37ae PF01780.19 OAP56381.1 - 0.86 9.7 3.2 6.4 6.9 0.2 2.6 1 1 1 2 2 2 0 Ribosomal L37ae protein family T6PP_N PF18572.1 OAP56381.1 - 1.3 8.9 5.2 19 5.1 0.0 3.5 4 0 0 4 4 3 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain Zn-ribbon_8 PF09723.10 OAP56381.1 - 1.3 9.2 4.5 6.9 6.9 3.2 2.5 1 1 1 2 2 2 0 Zinc ribbon domain Com_YlbF PF06133.11 OAP56381.1 - 1.6 9.4 4.4 0.73 10.5 0.3 2.5 2 0 0 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA zf-C2H2_6 PF13912.6 OAP56381.1 - 1.7 8.7 6.3 27 4.9 0.5 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger SNF2_N PF00176.23 OAP56382.1 - 7.8e-64 215.6 0.0 1.2e-63 215.0 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OAP56382.1 - 6.8e-12 45.7 0.0 1.8e-11 44.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAP56382.1 - 2.1e-07 31.1 0.0 5.1e-07 29.9 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 OAP56382.1 - 0.0028 16.9 0.0 0.0047 16.2 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase zf-C3HC4_3 PF13920.6 OAP56382.1 - 0.0071 16.2 4.8 0.015 15.1 4.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAP56382.1 - 0.015 15.2 6.2 0.029 14.3 6.2 1.5 1 0 0 1 1 1 0 zinc-RING finger domain Prok-RING_4 PF14447.6 OAP56382.1 - 0.061 13.2 6.2 0.13 12.1 6.2 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 SHR-BD PF06650.12 OAP56382.1 - 0.073 12.4 0.0 0.21 10.9 0.0 1.7 2 0 0 2 2 2 0 SHR-binding domain of vacuolar-sorting associated protein 13 DEAD_2 PF06733.15 OAP56382.1 - 0.13 11.8 0.0 0.3 10.7 0.0 1.6 1 0 0 1 1 1 0 DEAD_2 zf-RING_6 PF14835.6 OAP56382.1 - 0.33 10.9 6.1 0.65 9.9 3.3 2.3 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-C3HC4 PF00097.25 OAP56382.1 - 6.7 6.7 6.3 19 5.2 6.3 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF1275 PF06912.11 OAP56383.1 - 6.7e-43 146.8 18.2 8.8e-43 146.5 18.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) Fungal_trans PF04082.18 OAP56384.1 - 6.9e-10 38.4 0.0 1.1e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain AAA PF00004.29 OAP56385.1 - 4.2e-17 62.8 0.0 1.1e-16 61.4 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OAP56385.1 - 0.041 14.3 0.0 2 8.8 0.0 2.6 1 1 0 2 2 2 0 AAA ATPase domain SET PF00856.28 OAP56386.1 - 4.8e-10 40.1 0.0 1.2e-09 38.8 0.0 1.7 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.18 OAP56386.1 - 7.2e-08 32.4 10.1 7.2e-08 32.4 10.1 3.1 3 0 0 3 3 3 1 MYND finger Glyco_trans_1_4 PF13692.6 OAP56387.1 - 6.9e-09 36.2 0.0 0.00041 20.8 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 OAP56387.1 - 0.086 12.8 0.4 0.24 11.4 0.4 1.7 1 1 0 1 1 1 0 Glycosyltransferase Family 4 Cation_efflux PF01545.21 OAP56388.1 - 1.2e-44 152.4 4.8 1.7e-44 152.0 4.8 1.2 1 0 0 1 1 1 1 Cation efflux family MFS_3 PF05977.13 OAP56388.1 - 0.061 11.7 0.1 0.12 10.7 0.1 1.4 1 0 0 1 1 1 0 Transmembrane secretion effector TRP PF06011.12 OAP56388.1 - 0.073 11.8 0.0 2.7 6.6 0.0 2.1 2 0 0 2 2 2 0 Transient receptor potential (TRP) ion channel SKG6 PF08693.10 OAP56389.1 - 0.0035 16.7 0.5 0.0083 15.5 0.5 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain TMEM51 PF15345.6 OAP56389.1 - 0.029 14.2 0.0 0.075 12.9 0.0 1.7 2 0 0 2 2 2 0 Transmembrane protein 51 Rax2 PF12768.7 OAP56389.1 - 0.04 13.4 0.0 0.07 12.6 0.0 1.3 1 0 0 1 1 1 0 Cortical protein marker for cell polarity CcmD PF04995.14 OAP56389.1 - 0.042 13.9 1.3 0.042 13.9 1.3 1.7 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) DUF4448 PF14610.6 OAP56389.1 - 0.1 12.4 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) p450 PF00067.22 OAP56390.1 - 5.3e-55 187.0 0.0 1.4e-54 185.6 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 TFIIIC_delta PF12657.7 OAP56391.1 - 3.7e-27 95.4 0.9 6.8e-27 94.6 0.9 1.4 1 0 0 1 1 1 1 Transcription factor IIIC subunit delta N-term zf-TFIIIC PF12660.7 OAP56391.1 - 2.5e-22 78.7 0.6 5.1e-22 77.7 0.6 1.5 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex DUF2321 PF10083.9 OAP56391.1 - 0.13 11.9 0.3 0.31 10.6 0.3 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) zinc_ribbon_9 PF14369.6 OAP56391.1 - 0.34 11.2 3.4 6.4 7.1 0.2 2.7 2 0 0 2 2 2 0 zinc-ribbon HypA PF01155.19 OAP56391.1 - 0.35 10.9 0.8 3.2 7.8 0.4 2.3 2 1 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-TFIIB PF13453.6 OAP56391.1 - 1.2 8.5 3.6 13 5.2 0.3 2.9 3 0 0 3 3 3 0 Transcription factor zinc-finger DZR PF12773.7 OAP56391.1 - 1.3 9.1 5.5 30 4.7 5.5 2.4 1 1 0 1 1 1 0 Double zinc ribbon zf-ribbon_3 PF13248.6 OAP56391.1 - 3.6 7.1 8.5 2.8 7.5 0.3 2.8 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_2 PF13240.6 OAP56391.1 - 7.1 6.5 7.2 8.6 6.2 0.3 3.2 3 0 0 3 3 3 0 zinc-ribbon domain Ank_2 PF12796.7 OAP56393.1 - 1.2e-54 182.9 0.0 5e-13 49.5 0.0 4.6 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.30 OAP56393.1 - 2.1e-38 129.1 2.0 9.7e-07 29.0 0.0 7.6 7 0 0 7 7 7 6 Ankyrin repeat Ank_3 PF13606.6 OAP56393.1 - 5e-33 109.4 0.8 2.5e-05 24.3 0.0 7.4 7 0 0 7 7 7 6 Ankyrin repeat Ank_4 PF13637.6 OAP56393.1 - 3.1e-32 110.5 0.5 2.4e-12 47.1 0.0 5.8 2 2 5 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 OAP56393.1 - 1.1e-25 89.4 6.4 1.4e-08 34.8 0.1 6.0 2 1 5 7 7 6 6 Ankyrin repeats (many copies) NACHT PF05729.12 OAP56393.1 - 6.2e-06 26.2 2.3 2.4e-05 24.3 0.4 2.8 2 1 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 OAP56393.1 - 0.00015 22.1 0.3 0.00059 20.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OAP56393.1 - 0.0002 21.8 1.4 0.0026 18.2 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain HTH_Tnp_4 PF13613.6 OAP56393.1 - 0.011 15.5 3.2 0.047 13.4 0.5 2.9 3 0 0 3 3 3 0 Helix-turn-helix of DDE superfamily endonuclease ACOX PF01756.19 OAP56393.1 - 0.053 13.1 0.1 0.15 11.6 0.1 1.7 1 0 0 1 1 1 0 Acyl-CoA oxidase DUF2075 PF09848.9 OAP56393.1 - 0.058 12.6 0.0 0.15 11.3 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ATPase_2 PF01637.18 OAP56393.1 - 0.095 12.6 0.0 0.29 11.0 0.0 1.8 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea VWA_3_C PF18571.1 OAP56393.1 - 0.13 12.1 1.7 3.6 7.5 0.0 3.9 4 0 0 4 4 4 0 von Willebrand factor type A C-terminal domain Beta_protein PF14350.6 OAP56393.1 - 0.16 11.4 0.3 0.86 9.0 0.1 2.3 2 0 0 2 2 2 0 Beta protein AAA PF00004.29 OAP56393.1 - 0.16 12.4 0.0 0.9 10.0 0.0 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SesA PF17107.5 OAP56393.1 - 0.16 12.1 6.1 0.11 12.7 0.4 3.0 3 0 0 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases JIP_LZII PF16471.5 OAP56393.1 - 2 8.6 4.2 1.7 8.9 1.2 2.3 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II Fungal_trans PF04082.18 OAP56395.1 - 6.9e-27 94.1 0.0 2.7e-26 92.2 0.0 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP56395.1 - 2.4e-07 30.7 11.0 4.9e-07 29.8 11.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 5_3_exonuc_N PF02739.16 OAP56395.1 - 0.18 11.7 0.0 0.34 10.8 0.0 1.4 1 0 0 1 1 1 0 5'-3' exonuclease, N-terminal resolvase-like domain DUF4407 PF14362.6 OAP56395.1 - 2.7 7.2 5.0 2.8 7.2 3.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Cellulase PF00150.18 OAP56396.1 - 1.9e-26 93.1 2.0 5e-26 91.8 0.9 1.9 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) COesterase PF00135.28 OAP56397.1 - 1.2e-71 242.2 0.6 2.7e-71 241.0 0.6 1.4 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAP56397.1 - 1.1e-09 38.5 0.0 4.1e-09 36.6 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Glyco_hydro_10 PF00331.20 OAP56398.1 - 1e-77 261.4 0.0 1.2e-77 261.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Sugar_tr PF00083.24 OAP56399.1 - 2e-89 300.6 21.9 2.4e-89 300.3 21.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP56399.1 - 1.3e-28 99.9 22.8 3e-28 98.8 17.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 OAP56399.1 - 1.1e-06 27.4 3.6 2e-06 26.6 3.6 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DEAD PF00270.29 OAP56400.1 - 4.7e-47 160.0 0.0 7.4e-47 159.4 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAP56400.1 - 1.9e-31 108.7 0.1 3.1e-30 104.8 0.1 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAP56400.1 - 3.7e-05 23.8 0.0 7.5e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 OAP56400.1 - 0.00025 20.4 0.1 0.00043 19.6 0.1 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Flavi_DEAD PF07652.14 OAP56400.1 - 0.018 15.0 0.0 0.057 13.4 0.0 1.8 2 0 0 2 2 2 0 Flavivirus DEAD domain AMP-binding PF00501.28 OAP56401.1 - 2.5e-74 250.4 0.0 3.5e-74 249.9 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 OAP56401.1 - 1.8e-60 204.3 0.0 3.4e-60 203.4 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein adh_short PF00106.25 OAP56401.1 - 8.2e-52 175.5 0.7 1.3e-51 174.8 0.7 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP56401.1 - 3.1e-38 131.6 1.6 3.6e-38 131.4 0.7 1.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP56401.1 - 4.6e-17 62.5 0.7 1.6e-14 54.2 0.8 2.4 2 0 0 2 2 2 2 KR domain Epimerase PF01370.21 OAP56401.1 - 6.4e-15 55.3 0.0 1.6e-08 34.3 0.0 3.1 2 2 0 2 2 2 2 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 OAP56401.1 - 3.4e-11 43.3 0.0 9.2e-11 42.0 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.19 OAP56401.1 - 1.6e-08 33.9 0.1 5.5e-06 25.6 0.0 3.0 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 OAP56401.1 - 1.7e-06 27.4 0.2 0.0042 16.2 0.0 2.9 3 0 0 3 3 3 2 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 OAP56401.1 - 1.6e-05 24.2 0.2 0.025 13.7 0.1 3.1 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein AMP-binding_C PF13193.6 OAP56401.1 - 0.00031 21.6 2.6 0.00083 20.3 0.5 3.0 3 0 0 3 3 2 1 AMP-binding enzyme C-terminal domain GDP_Man_Dehyd PF16363.5 OAP56401.1 - 0.018 14.4 0.0 3.6 6.9 0.0 2.3 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase DFP PF04127.15 OAP56401.1 - 0.04 13.7 0.3 0.31 10.8 0.4 2.3 3 0 0 3 3 3 0 DNA / pantothenate metabolism flavoprotein Cpn60_TCP1 PF00118.24 OAP56402.1 - 6.5e-167 556.1 4.4 7.5e-167 555.9 4.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family BRK PF07533.16 OAP56402.1 - 0.18 11.5 0.1 0.36 10.5 0.1 1.5 1 0 0 1 1 1 0 BRK domain Alpha-amylase PF00128.24 OAP56403.1 - 1.2e-111 373.6 0.0 1.8e-111 372.9 0.0 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.6 OAP56403.1 - 0.027 13.6 0.0 0.045 12.8 0.0 1.2 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain Sugar_tr PF00083.24 OAP56404.1 - 1.1e-74 252.0 18.4 1.2e-74 251.8 18.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP56404.1 - 2.6e-22 79.2 21.6 2.6e-22 79.2 21.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DnaJ PF00226.31 OAP56406.1 - 1.4e-19 70.0 0.9 2.7e-19 69.1 0.9 1.5 1 0 0 1 1 1 1 DnaJ domain Aminotran_1_2 PF00155.21 OAP56407.1 - 6.3e-64 216.4 0.0 7.4e-64 216.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 OAP56407.1 - 0.12 10.9 0.0 0.22 10.0 0.0 1.4 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme zf-C2H2_jaz PF12171.8 OAP56409.1 - 1.2e-08 34.9 0.7 2.5e-08 34.0 0.7 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OAP56409.1 - 5.6e-08 32.9 0.8 9.8e-08 32.2 0.8 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-DBF PF07535.12 OAP56409.1 - 0.0011 19.0 0.4 0.0027 17.8 0.4 1.5 1 0 0 1 1 1 1 DBF zinc finger Jak1_Phl PF17887.1 OAP56409.1 - 0.62 10.0 10.5 0.34 10.9 4.4 2.2 2 0 0 2 2 2 0 Jak1 pleckstrin homology-like domain Pyrid_ox_like PF16242.5 OAP56410.1 - 8.6e-24 83.8 0.0 1.2e-23 83.3 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like Putative_PNPOx PF01243.20 OAP56410.1 - 1.5e-08 34.7 0.0 2.6e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase FMN_bind_2 PF04299.12 OAP56410.1 - 0.00091 19.0 0.0 0.0017 18.1 0.0 1.5 1 1 0 1 1 1 1 Putative FMN-binding domain DEAD PF00270.29 OAP56411.1 - 3.3e-46 157.2 0.0 6.7e-46 156.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAP56411.1 - 2.8e-17 63.1 0.0 2.3e-16 60.1 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAP56411.1 - 2.8e-06 27.5 0.0 4.7e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 OAP56411.1 - 0.092 11.9 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase CMS1 PF14617.6 OAP56411.1 - 0.16 11.3 0.0 0.31 10.4 0.0 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Aldolase_II PF00596.21 OAP56412.1 - 2.4e-49 167.8 0.0 3.1e-49 167.4 0.0 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain SGL PF08450.12 OAP56413.1 - 7.2e-08 32.3 0.1 1.1e-07 31.7 0.1 1.2 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 OAP56413.1 - 0.026 14.7 0.0 0.059 13.6 0.0 1.6 1 0 0 1 1 1 0 Arylesterase zf-CRD PF17979.1 OAP56414.1 - 0.011 15.8 2.2 0.017 15.2 2.2 1.3 1 0 0 1 1 1 0 Cysteine rich domain with multizinc binding regions zf-FLZ PF04570.14 OAP56414.1 - 0.12 11.8 3.8 0.71 9.4 0.5 2.4 1 1 1 2 2 2 0 zinc-finger of the FCS-type, C2-C2 BIR PF00653.21 OAP56415.1 - 9.9e-47 157.5 2.5 5.8e-23 81.3 0.0 2.4 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain FancD2 PF14631.6 OAP56415.1 - 5 4.4 4.6 6.4 4.0 4.6 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease Tam41_Mmp37 PF09139.11 OAP56416.1 - 1.1e-129 432.5 0.0 1.4e-129 432.2 0.0 1.0 1 0 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial MAPEG PF01124.18 OAP56417.1 - 5.3e-13 49.0 4.2 6.8e-13 48.7 4.2 1.2 1 0 0 1 1 1 1 MAPEG family NAD_binding_2 PF03446.15 OAP56420.1 - 5.4e-28 98.2 0.0 1.2e-27 97.1 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 OAP56420.1 - 6.4e-24 84.5 0.1 9.3e-21 74.3 0.0 2.8 3 0 0 3 3 3 2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 OAP56420.1 - 2e-06 28.3 0.1 8.4e-06 26.3 0.0 2.2 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 OAP56420.1 - 0.0022 17.9 0.0 0.0063 16.4 0.0 1.8 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 OAP56420.1 - 0.13 11.8 0.0 1 8.9 0.0 2.2 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UBA_e1_thiolCys PF10585.9 OAP56422.1 - 0.067 13.1 3.0 0.14 12.1 3.0 1.5 1 0 0 1 1 1 0 Ubiquitin-activating enzyme active site SUIM_assoc PF16619.5 OAP56422.1 - 0.23 11.6 16.3 0.25 11.4 4.9 3.9 3 1 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 DUF2722 PF10846.8 OAP56422.1 - 0.56 9.1 0.0 0.56 9.1 0.0 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF2722) RabGAP-TBC PF00566.18 OAP56423.1 - 3e-33 115.3 0.0 4.6e-33 114.7 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Sas10_Utp3 PF04000.15 OAP56424.1 - 1.4e-14 54.4 0.1 3.8e-14 53.1 0.1 1.7 1 0 0 1 1 1 1 Sas10/Utp3/C1D family DMAP_binding PF06464.11 OAP56424.1 - 2.5 9.0 9.4 1.1 10.0 2.3 2.6 2 0 0 2 2 2 0 DMAP1-binding Domain Tautomerase_3 PF14832.6 OAP56425.1 - 2.4e-45 154.1 0.1 2.7e-45 154.0 0.1 1.0 1 0 0 1 1 1 1 Putative oxalocrotonate tautomerase enzyme Tautomerase PF01361.21 OAP56425.1 - 0.00012 22.0 0.0 0.00048 20.0 0.0 1.9 1 1 1 2 2 2 1 Tautomerase enzyme Peptidase_C13 PF01650.18 OAP56426.1 - 4.2e-40 137.9 0.0 5.8e-40 137.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase C13 family DUF4023 PF13215.6 OAP56427.1 - 0.00026 20.9 0.1 0.00026 20.9 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF4023) F-box-like PF12937.7 OAP56427.1 - 0.015 15.2 4.7 0.047 13.6 0.1 3.0 3 0 0 3 3 3 0 F-box-like TFIID_20kDa PF03847.13 OAP56427.1 - 0.019 15.5 0.0 0.036 14.6 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Fasciclin PF02469.22 OAP56428.1 - 2e-24 86.2 0.0 1.8e-15 57.3 0.1 2.3 2 0 0 2 2 2 2 Fasciclin domain DUF347 PF03988.12 OAP56428.1 - 0.053 13.7 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) SKG6 PF08693.10 OAP56428.1 - 0.1 12.0 0.1 0.21 11.0 0.1 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Polysacc_deac_1 PF01522.21 OAP56429.1 - 8e-18 64.5 0.0 2.2e-17 63.1 0.0 1.7 1 1 0 1 1 1 1 Polysaccharide deacetylase DUF1043 PF06295.12 OAP56429.1 - 0.1 12.6 0.0 0.13 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) FlxA PF14282.6 OAP56429.1 - 0.11 12.5 0.9 0.16 11.9 0.9 1.2 1 0 0 1 1 1 0 FlxA-like protein CDC45 PF02724.14 OAP56430.1 - 1.6e-232 773.4 10.9 7.6e-231 767.8 10.9 3.1 1 1 0 1 1 1 1 CDC45-like protein SDA1 PF05285.12 OAP56430.1 - 0.063 12.7 32.7 0.35 10.3 15.5 2.1 2 0 0 2 2 2 0 SDA1 Cwf_Cwc_15 PF04889.12 OAP56430.1 - 0.098 12.4 30.3 0.092 12.5 14.4 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 OAP56430.1 - 0.14 10.3 29.8 0.66 8.1 7.2 2.1 2 0 0 2 2 2 0 Nop14-like family Tom22 PF04281.13 OAP56430.1 - 0.33 10.7 0.0 0.33 10.7 0.0 3.4 3 0 0 3 3 3 0 Mitochondrial import receptor subunit Tom22 DUF3446 PF11928.8 OAP56430.1 - 3 8.2 20.1 0.27 11.6 0.9 3.2 3 0 0 3 3 3 0 Early growth response N-terminal domain TFIIF_alpha PF05793.12 OAP56430.1 - 3.5 6.1 34.1 2.3 6.7 17.4 2.2 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Menin PF05053.13 OAP56430.1 - 7.5 4.8 15.4 0.23 9.8 4.0 2.1 2 0 0 2 2 2 0 Menin Apt1 PF10351.9 OAP56430.1 - 8.7 5.1 19.3 3.4 6.4 8.4 2.3 2 0 0 2 2 2 0 Golgi-body localisation protein domain Lipase_GDSL_2 PF13472.6 OAP56431.1 - 9e-16 58.8 0.1 1.9e-15 57.7 0.1 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 OAP56431.1 - 6.3e-05 23.0 0.0 0.00011 22.3 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DHH PF01368.20 OAP56432.1 - 3.2e-05 24.1 0.2 5.3e-05 23.4 0.2 1.4 1 0 0 1 1 1 1 DHH family DUF5572 PF17733.1 OAP56432.1 - 0.11 12.3 0.2 0.32 10.8 0.2 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5572) p450 PF00067.22 OAP56433.1 - 6.5e-66 223.0 0.0 8.2e-66 222.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Med4 PF10018.9 OAP56434.1 - 5.9e-24 84.8 4.3 1.1e-23 83.9 4.3 1.5 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 MFS_1 PF07690.16 OAP56436.1 - 3.1e-23 82.3 15.1 3.1e-23 82.3 15.1 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAP56436.1 - 2.4e-12 46.5 2.7 2.4e-12 46.5 2.7 2.8 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 OAP56436.1 - 5.7e-07 28.3 3.4 1.1e-06 27.3 3.4 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) RabGAP-TBC PF00566.18 OAP56437.1 - 2.4e-49 167.9 0.0 5.5e-49 166.7 0.0 1.7 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF812 PF05667.11 OAP56437.1 - 6e-05 22.1 14.7 0.00011 21.3 14.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF812) CENP-H PF05837.12 OAP56437.1 - 0.2 12.1 21.9 0.085 13.3 4.8 3.8 3 0 0 3 3 3 0 Centromere protein H (CENP-H) ArAE_2_N PF10337.9 OAP56437.1 - 0.23 10.4 2.5 1.3 8.0 0.0 2.1 1 1 1 2 2 2 0 Putative ER transporter, 6TM, N-terminal Occludin_ELL PF07303.13 OAP56437.1 - 1.5 9.6 11.3 3.3 8.5 2.6 2.8 2 0 0 2 2 2 0 Occludin homology domain T3SSipB PF16535.5 OAP56437.1 - 3.5 8.1 11.7 0.11 13.0 1.4 2.7 2 0 0 2 2 2 0 Type III cell invasion protein SipB DivIC PF04977.15 OAP56437.1 - 5.6 6.8 10.4 16 5.3 1.0 3.3 2 0 0 2 2 2 0 Septum formation initiator DUF3450 PF11932.8 OAP56437.1 - 6.4 6.0 22.9 0.18 11.1 5.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) D5_N PF08706.11 OAP56437.1 - 7.8 6.8 6.0 1.3 9.2 0.5 2.2 2 0 0 2 2 2 0 D5 N terminal like HrpB2 PF09487.10 OAP56437.1 - 9 6.8 7.4 17 5.9 0.3 3.5 2 1 1 3 3 3 0 Bacterial type III secretion protein (HrpB2) DNA_topoisoIV PF00521.20 OAP56438.1 - 6.1e-138 460.3 1.9 2.2e-137 458.4 0.0 2.3 2 1 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 OAP56438.1 - 2.8e-52 176.4 6.1 2.8e-52 176.4 6.1 3.3 4 0 0 4 4 4 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 OAP56438.1 - 7.1e-29 100.5 6.4 1.7e-28 99.3 6.4 1.6 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 OAP56438.1 - 1.2e-14 54.8 0.1 3.9e-14 53.1 0.1 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 OAP56438.1 - 4.8e-07 29.9 0.0 3.1e-06 27.4 0.0 2.5 1 0 0 1 1 1 1 Toprim domain NusA_N PF08529.11 OAP56438.1 - 0.066 13.6 0.1 0.066 13.6 0.1 4.7 5 1 1 6 6 6 0 NusA N-terminal domain LIDHydrolase PF10230.9 OAP56438.1 - 0.17 11.4 2.2 0.3 10.6 0.3 2.2 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase DUF5638 PF18688.1 OAP56440.1 - 0.097 13.0 0.0 0.17 12.2 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5638) zf_CCCH_4 PF18345.1 OAP56440.1 - 0.64 10.2 12.6 0.052 13.6 2.8 3.3 3 0 0 3 3 3 0 Zinc finger domain zf-CCCH PF00642.24 OAP56440.1 - 4.6 7.3 10.6 2.8 8.0 1.9 3.1 2 1 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) PLA2G12 PF06951.11 OAP56442.1 - 3.6e-09 36.8 7.8 5.7e-09 36.1 7.8 1.2 1 0 0 1 1 1 1 Group XII secretory phospholipase A2 precursor (PLA2G12) F-box PF00646.33 OAP56443.1 - 5.1e-05 23.0 0.3 0.0001 22.1 0.3 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 OAP56443.1 - 0.3 11.0 4.9 0.3 11.0 0.6 2.8 3 0 0 3 3 3 0 F-box-like MFS_1 PF07690.16 OAP56444.1 - 3.7e-28 98.5 29.8 3.7e-28 98.5 29.8 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 OAP56444.1 - 0.0076 14.6 5.2 0.015 13.6 1.1 2.3 2 0 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family PsbY PF06298.11 OAP56444.1 - 0.009 15.9 0.2 0.009 15.9 0.2 2.1 2 0 0 2 2 2 1 Photosystem II protein Y (PsbY) DUF5360 PF17314.2 OAP56444.1 - 0.97 9.5 6.5 0.68 10.0 0.1 3.1 3 0 0 3 3 3 0 Family of unknown function (DUF5360) FAA_hydrolase PF01557.18 OAP56445.1 - 1.7e-60 204.4 0.0 2.1e-60 204.1 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAD_binding_3 PF01494.19 OAP56446.1 - 1.2e-23 83.9 0.2 4.3e-10 39.4 0.0 3.0 3 0 0 3 3 3 3 FAD binding domain NAD_binding_8 PF13450.6 OAP56446.1 - 0.00052 20.2 0.0 0.0012 19.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAP56446.1 - 0.016 14.5 0.0 0.2 10.8 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 OAP56446.1 - 0.018 14.1 0.0 0.6 9.1 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase Pyr_redox_3 PF13738.6 OAP56446.1 - 0.025 13.8 0.0 0.059 12.6 0.0 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAP56446.1 - 0.057 12.7 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.12 OAP56446.1 - 0.083 11.9 0.1 0.53 9.3 0.0 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein HI0933_like PF03486.14 OAP56446.1 - 0.22 10.2 0.0 0.82 8.3 0.0 1.8 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox PF00070.27 OAP56446.1 - 0.99 10.0 0.0 0.99 10.0 0.0 2.5 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase p450 PF00067.22 OAP56447.1 - 6.9e-54 183.3 0.0 8.8e-54 183.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.18 OAP56448.1 - 3.7e-10 39.3 0.2 5.5e-10 38.7 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP56448.1 - 4.3e-08 33.1 10.0 9.6e-08 32.0 10.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CBP4 PF07960.11 OAP56448.1 - 0.043 13.7 0.2 0.08 12.8 0.2 1.4 1 0 0 1 1 1 0 CBP4 FAD_binding_3 PF01494.19 OAP56449.1 - 1.3e-18 67.4 0.0 1.9e-11 43.8 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 OAP56449.1 - 1.1e-10 41.3 0.2 0.00041 19.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAP56449.1 - 2.8e-07 30.5 0.8 0.0024 17.5 0.8 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.14 OAP56449.1 - 3.3e-07 29.4 0.1 0.0028 16.4 0.1 2.2 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.24 OAP56449.1 - 1.6e-06 27.5 0.1 1.6e-05 24.2 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 OAP56449.1 - 1.9e-06 27.2 0.6 0.11 11.5 0.0 3.1 3 0 0 3 3 3 2 Lycopene cyclase protein NAD_binding_8 PF13450.6 OAP56449.1 - 2.4e-05 24.5 0.2 5.3e-05 23.4 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 OAP56449.1 - 0.00016 21.1 0.0 0.026 13.8 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OAP56449.1 - 0.00025 20.2 0.9 0.0029 16.8 0.1 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 OAP56449.1 - 0.00049 19.5 0.0 0.00091 18.6 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 OAP56449.1 - 0.00063 19.2 0.0 0.0011 18.5 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 OAP56449.1 - 0.0047 17.5 0.2 0.34 11.5 0.2 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 OAP56449.1 - 0.043 13.1 0.1 2.8 7.1 0.0 2.5 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase Trp_halogenase PF04820.14 OAP56449.1 - 0.052 12.4 0.2 6.6 5.5 0.1 2.4 2 0 0 2 2 2 0 Tryptophan halogenase NAD_binding_9 PF13454.6 OAP56449.1 - 0.079 12.9 1.6 0.95 9.4 1.6 2.3 1 1 0 1 1 1 0 FAD-NAD(P)-binding Thi4 PF01946.17 OAP56449.1 - 0.11 11.8 0.0 0.26 10.5 0.0 1.6 1 0 0 1 1 1 0 Thi4 family TPP_enzyme_N PF02776.18 OAP56450.1 - 2.1e-33 115.4 0.0 4.2e-33 114.4 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 OAP56450.1 - 2.3e-16 59.8 0.0 5e-16 58.7 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 OAP56450.1 - 1.3e-11 44.5 1.5 3.1e-11 43.3 0.1 2.2 2 1 1 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Glyoxalase PF00903.25 OAP56451.1 - 7.5e-14 52.0 0.1 1e-13 51.6 0.1 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 OAP56451.1 - 0.0037 18.1 0.0 0.007 17.1 0.0 1.4 1 0 0 1 1 1 1 Glyoxalase-like domain MMR_HSR1 PF01926.23 OAP56452.1 - 1.4e-11 44.5 0.0 2.5e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 OAP56452.1 - 1.7e-07 30.8 0.0 2.5e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 OAP56452.1 - 4.9e-05 23.3 0.0 0.00011 22.2 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase FeoB_N PF02421.18 OAP56452.1 - 0.0078 15.8 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Guanylate_kin PF00625.21 OAP56452.1 - 0.014 15.1 0.0 0.027 14.2 0.0 1.4 1 0 0 1 1 1 0 Guanylate kinase ABC_tran PF00005.27 OAP56452.1 - 0.033 14.7 0.0 0.054 14.0 0.0 1.3 1 0 0 1 1 1 0 ABC transporter AAA_16 PF13191.6 OAP56452.1 - 0.064 13.6 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 OAP56452.1 - 0.12 12.1 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Dynamin_N PF00350.23 OAP56452.1 - 0.2 11.7 0.1 6.5 6.8 0.2 2.2 1 1 1 2 2 2 0 Dynamin family PCI PF01399.27 OAP56455.1 - 0.0069 16.9 0.0 3 8.4 0.0 3.0 3 0 0 3 3 3 1 PCI domain SID-1_RNA_chan PF13965.6 OAP56455.1 - 0.017 13.5 0.1 0.026 13.0 0.1 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 TPR_2 PF07719.17 OAP56455.1 - 0.02 15.0 0.2 0.054 13.6 0.2 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_19 PF14559.6 OAP56455.1 - 0.099 13.2 0.0 0.52 10.8 0.0 2.1 1 1 0 1 1 1 0 Tetratricopeptide repeat ANAPC3 PF12895.7 OAP56455.1 - 0.6 10.4 3.8 0.54 10.5 1.0 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Sof1 PF04158.14 OAP56456.1 - 1e-31 109.0 14.2 1.8e-31 108.2 14.2 1.4 1 0 0 1 1 1 1 Sof1-like domain WD40 PF00400.32 OAP56456.1 - 6e-30 102.8 6.8 5e-06 27.2 0.1 6.9 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAP56456.1 - 6.4e-08 32.8 0.4 0.3 11.4 0.1 4.4 2 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OAP56456.1 - 0.00023 20.3 0.0 0.024 13.6 0.0 2.7 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein RPN6_N PF18055.1 OAP56457.1 - 8.2e-46 155.2 2.8 2.2e-45 153.8 0.2 2.7 3 0 0 3 3 3 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 OAP56457.1 - 1.1e-20 74.1 1.0 3e-20 72.7 0.3 2.1 2 0 0 2 2 2 1 PCI domain RPN6_C_helix PF18503.1 OAP56457.1 - 9.6e-12 44.4 0.5 2.3e-11 43.2 0.5 1.7 1 0 0 1 1 1 1 26S proteasome subunit RPN6 C-terminal helix domain DDRGK PF09756.9 OAP56457.1 - 0.00012 21.7 0.4 0.00026 20.6 0.4 1.5 1 0 0 1 1 1 1 DDRGK domain TPR_7 PF13176.6 OAP56457.1 - 0.0056 16.6 3.7 2.5 8.3 0.1 4.7 3 1 2 5 5 5 1 Tetratricopeptide repeat TPR_MalT PF17874.1 OAP56457.1 - 0.0084 15.5 10.5 0.024 14.0 3.4 3.2 2 1 1 3 3 3 1 MalT-like TPR region HTH_Crp_2 PF13545.6 OAP56457.1 - 0.011 15.7 0.0 1.2 9.1 0.0 2.8 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain ABC_membrane_2 PF06472.15 OAP56457.1 - 0.033 13.6 0.1 0.057 12.8 0.1 1.4 1 0 0 1 1 1 0 ABC transporter transmembrane region 2 SbsC_C PF18058.1 OAP56457.1 - 0.28 11.4 5.5 0.06 13.6 0.6 2.4 2 0 0 2 2 2 0 SbsC C-terminal domain DUF4456 PF14644.6 OAP56457.1 - 0.55 9.9 6.2 2.3 7.9 0.7 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4456) TPR_6 PF13174.6 OAP56457.1 - 1.8 9.4 10.5 15 6.5 0.1 5.6 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_1 PF00515.28 OAP56457.1 - 3.6 7.5 6.2 32 4.5 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF4398 PF14346.6 OAP56457.1 - 5 7.8 15.1 0.52 11.0 2.8 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4398) TPR_19 PF14559.6 OAP56457.1 - 5.9 7.5 8.6 2.9 8.5 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat EF-hand_6 PF13405.6 OAP56458.1 - 4.2e-25 85.5 4.8 7.9e-07 28.5 0.1 5.2 5 0 0 5 5 5 4 EF-hand domain EF-hand_7 PF13499.6 OAP56458.1 - 5.9e-25 87.5 8.2 6.4e-16 58.6 0.6 3.1 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 OAP56458.1 - 9e-25 84.3 12.1 3.4e-08 32.5 0.1 4.8 5 0 0 5 5 5 3 EF hand EF-hand_5 PF13202.6 OAP56458.1 - 3e-17 61.2 11.9 4.7e-05 22.7 0.1 4.8 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.6 OAP56458.1 - 3e-14 52.6 14.3 1.2e-05 25.1 0.9 4.1 3 2 1 4 4 4 3 EF-hand domain pair EF-hand_4 PF12763.7 OAP56458.1 - 1.8e-08 34.2 6.1 0.0021 18.0 0.1 3.9 1 1 2 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 OAP56458.1 - 9.7e-05 22.6 0.6 0.0035 17.6 0.1 3.0 2 1 1 3 3 3 1 EF-hand domain SPARC_Ca_bdg PF10591.9 OAP56458.1 - 0.00088 19.6 2.5 0.97 9.8 0.2 3.1 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 OAP56458.1 - 0.0039 17.0 2.0 0.88 9.5 0.0 3.6 5 0 0 5 5 5 1 EF hand DUF1679 PF07914.11 OAP56458.1 - 0.023 13.5 0.5 1.9 7.2 0.1 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1679) Staphylokinase PF02821.16 OAP56458.1 - 0.029 14.8 0.0 3.7 8.0 0.0 2.5 1 1 1 2 2 2 0 Staphylokinase/Streptokinase family EF-hand_14 PF17959.1 OAP56458.1 - 0.3 11.5 1.6 12 6.3 0.0 3.4 4 0 0 4 4 4 0 EF-hand domain EMP70 PF02990.16 OAP56459.1 - 5.3e-199 662.2 0.1 6.6e-199 661.9 0.1 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 PalH PF08733.10 OAP56459.1 - 0.88 8.5 8.3 0.27 10.2 0.1 2.7 3 0 0 3 3 3 0 PalH/RIM21 HATPase_c PF02518.26 OAP56460.1 - 1.3e-22 80.4 0.2 3.6e-22 79.0 0.1 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 OAP56460.1 - 1.7e-20 73.3 0.0 4.2e-20 72.0 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 OAP56460.1 - 9.3e-16 57.6 0.0 2.1e-15 56.5 0.0 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.12 OAP56460.1 - 9.9e-11 41.8 0.3 7.4e-05 23.0 0.0 3.7 3 0 0 3 3 3 3 PAS fold PAS_4 PF08448.10 OAP56460.1 - 0.0025 18.0 0.0 0.074 13.3 0.0 2.8 3 0 0 3 3 3 1 PAS fold PAS PF00989.25 OAP56460.1 - 0.16 11.9 0.0 0.75 9.8 0.0 2.2 2 0 0 2 2 2 0 PAS fold KxDL PF10241.9 OAP56461.1 - 3.8e-29 100.8 3.4 5.5e-29 100.3 3.4 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein DUF4407 PF14362.6 OAP56461.1 - 0.54 9.5 5.5 0.65 9.3 5.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TMF_DNA_bd PF12329.8 OAP56461.1 - 8.2 6.5 10.1 6.7 6.8 1.9 2.1 1 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding SNRNP27 PF08648.12 OAP56462.1 - 0.11 12.6 0.2 0.18 11.9 0.2 1.4 1 0 0 1 1 1 0 U4/U6.U5 small nuclear ribonucleoproteins GMC_oxred_N PF00732.19 OAP56463.1 - 2.6e-47 161.7 0.0 7.7e-47 160.1 0.0 1.7 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAP56463.1 - 8.2e-34 117.2 0.1 1.2e-33 116.6 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 OAP56463.1 - 7e-05 23.0 0.6 0.00039 20.6 0.2 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAP56463.1 - 0.00043 20.0 0.3 0.034 13.7 0.1 2.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAP56463.1 - 0.0071 15.6 0.1 0.58 9.3 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OAP56463.1 - 0.015 14.4 0.0 0.055 12.5 0.0 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 OAP56464.1 - 1.8e-11 43.9 0.0 4.3e-08 32.8 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 OAP56464.1 - 1.7e-09 36.6 0.1 8.3e-09 34.4 0.0 2.1 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 OAP56464.1 - 9.5e-08 31.6 0.0 0.0017 17.7 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAP56464.1 - 4.7e-05 23.5 1.0 6.9e-05 23.0 0.0 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 OAP56464.1 - 0.00021 20.5 0.2 0.068 12.3 0.0 2.6 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Shikimate_DH PF01488.20 OAP56464.1 - 0.00053 20.1 0.0 0.91 9.6 0.0 2.6 2 1 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.24 OAP56464.1 - 0.004 16.3 0.0 0.0061 15.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAP56464.1 - 0.0079 15.8 0.5 0.13 11.8 0.3 2.6 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 OAP56464.1 - 0.02 14.2 0.3 0.038 13.2 0.3 1.4 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.6 OAP56464.1 - 0.16 11.9 0.0 4.5 7.2 0.0 2.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding 2-Hacid_dh_C PF02826.19 OAP56464.1 - 0.17 11.2 0.8 0.31 10.4 0.0 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DSPc PF00782.20 OAP56465.1 - 1.2e-18 67.2 0.0 3.8e-18 65.6 0.0 1.7 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 OAP56465.1 - 0.002 17.7 0.0 0.0035 17.0 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase COesterase PF00135.28 OAP56466.1 - 1.1e-38 133.4 0.0 8.4e-31 107.4 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 OAP56466.1 - 0.034 14.0 0.0 0.068 13.0 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold TFR_dimer PF04253.15 OAP56467.1 - 1.9e-32 111.9 0.0 3.6e-32 111.0 0.0 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 OAP56467.1 - 3.5e-19 69.3 0.0 1.5e-18 67.2 0.0 2.0 2 0 0 2 2 2 1 Peptidase family M28 PA PF02225.22 OAP56467.1 - 1.6e-12 47.2 0.1 5.5e-12 45.5 0.1 1.9 1 1 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 OAP56467.1 - 0.053 13.2 0.0 0.099 12.3 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 PRP3 PF08572.10 OAP56468.1 - 1.8e-72 243.7 3.2 3.1e-72 242.9 3.2 1.4 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 OAP56468.1 - 8.3e-45 152.5 1.0 1.9e-44 151.3 1.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) DUF3421 PF11901.8 OAP56468.1 - 0.026 14.5 0.0 0.054 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3421) PIN_3 PF13470.6 OAP56468.1 - 3.8 8.3 5.7 94 3.8 0.1 3.4 3 0 0 3 3 3 0 PIN domain adh_short_C2 PF13561.6 OAP56469.1 - 5.5e-21 75.2 0.0 3.5e-12 46.4 0.0 2.6 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP56469.1 - 9.8e-21 74.1 0.0 9e-15 54.6 0.0 2.3 1 1 1 2 2 2 2 short chain dehydrogenase Epimerase PF01370.21 OAP56469.1 - 0.0039 16.7 0.0 0.0095 15.4 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.10 OAP56469.1 - 0.076 12.9 0.1 2.5 8.0 0.1 2.1 1 1 0 1 1 1 0 KR domain GST_N_3 PF13417.6 OAP56470.1 - 9.8e-14 51.5 0.0 3.2e-13 49.9 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 OAP56470.1 - 1.7e-13 50.7 0.0 3.4e-13 49.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OAP56470.1 - 7.6e-13 48.5 0.1 1.3e-12 47.8 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 OAP56470.1 - 6.4e-12 45.6 0.1 2.8e-11 43.5 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 OAP56470.1 - 4.9e-09 36.3 0.1 8e-09 35.6 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OAP56470.1 - 0.0066 16.4 0.3 0.031 14.3 0.1 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Plant_NMP1 PF06694.11 OAP56470.1 - 0.059 12.5 0.0 0.08 12.0 0.0 1.2 1 0 0 1 1 1 0 Plant nuclear matrix protein 1 (NMP1) Tom37 PF10568.9 OAP56470.1 - 0.06 13.7 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein Sugar_tr PF00083.24 OAP56471.1 - 1.9e-85 287.4 18.8 2.3e-85 287.2 18.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP56471.1 - 2e-25 89.5 44.1 2.5e-22 79.3 22.8 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 OAP56471.1 - 0.00092 17.8 4.2 0.00092 17.8 4.2 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) PUCC PF03209.15 OAP56471.1 - 0.0039 16.3 14.8 0.0039 16.3 14.8 1.8 2 0 0 2 2 2 1 PUCC protein MFS_1_like PF12832.7 OAP56471.1 - 1.1 8.0 16.5 0.73 8.6 9.4 2.6 1 1 0 2 2 2 0 MFS_1 like family p450 PF00067.22 OAP56472.1 - 2e-66 224.7 0.0 2.5e-66 224.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.25 OAP56473.1 - 9.4e-41 139.4 0.1 1.1e-40 139.2 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP56473.1 - 2.9e-26 92.4 0.0 3.4e-26 92.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP56473.1 - 4.9e-08 33.1 0.1 7.3e-08 32.5 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAP56473.1 - 2.4e-06 27.2 0.3 0.001 18.6 0.1 2.0 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 OAP56473.1 - 0.00044 19.7 0.0 0.00053 19.4 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Polysacc_synt_2 PF02719.15 OAP56473.1 - 0.0061 15.7 0.0 0.0082 15.3 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 OAP56473.1 - 0.0079 15.2 0.1 0.01 14.8 0.1 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 OAP56473.1 - 0.015 15.2 0.9 0.022 14.7 0.9 1.3 1 0 0 1 1 1 0 NAD(P)H-binding Fungal_trans PF04082.18 OAP56474.1 - 1.5e-18 66.8 0.0 2.3e-18 66.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short_C2 PF13561.6 OAP56475.1 - 8.3e-36 123.7 0.0 9.1e-36 123.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP56475.1 - 8.6e-20 71.0 0.0 1.1e-19 70.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAP56475.1 - 0.0052 16.7 0.0 0.0066 16.4 0.0 1.1 1 0 0 1 1 1 1 KR domain MFS_1 PF07690.16 OAP56476.1 - 1.5e-35 122.7 19.9 1.5e-35 122.7 19.9 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAP56476.1 - 9.8e-15 54.3 4.8 9.8e-15 54.3 4.8 2.9 2 1 0 3 3 3 2 Sugar (and other) transporter FMO-like PF00743.19 OAP56477.1 - 7e-10 37.9 0.7 8e-06 24.5 0.0 3.1 1 1 1 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OAP56477.1 - 4.1e-08 33.3 0.0 1e-07 32.0 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 OAP56477.1 - 2.4e-05 24.3 0.0 0.023 14.7 0.0 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 OAP56477.1 - 0.00013 21.4 0.1 0.004 16.5 0.0 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAP56477.1 - 0.00022 20.5 0.0 0.023 13.8 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) MCRA PF06100.11 OAP56477.1 - 0.0015 17.4 0.0 0.0022 16.9 0.0 1.2 1 0 0 1 1 1 1 MCRA family Pyr_redox_2 PF07992.14 OAP56477.1 - 0.0084 15.4 0.0 0.4 9.8 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DUF498 PF04430.14 OAP56477.1 - 0.047 13.8 0.5 1.6 8.8 0.0 3.2 5 0 0 5 5 5 0 Protein of unknown function (DUF498/DUF598) NAD_binding_7 PF13241.6 OAP56477.1 - 0.056 13.9 0.0 1.6 9.2 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding Shikimate_DH PF01488.20 OAP56477.1 - 0.23 11.5 0.0 16 5.6 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase CoA_transf_3 PF02515.17 OAP56478.1 - 2e-37 129.2 0.1 1.8e-34 119.4 0.1 2.8 2 1 0 2 2 2 2 CoA-transferase family III DLH PF01738.18 OAP56478.1 - 3.3e-20 72.6 0.0 6.1e-20 71.7 0.0 1.4 1 0 0 1 1 1 1 Dienelactone hydrolase family PQ-loop PF04193.14 OAP56479.1 - 0.0024 17.6 0.2 0.0024 17.6 0.2 2.1 2 0 0 2 2 2 1 PQ loop repeat MARVEL PF01284.23 OAP56479.1 - 0.01 15.8 18.8 0.18 11.8 18.7 2.0 1 1 0 1 1 1 0 Membrane-associating domain DUF3789 PF12664.7 OAP56479.1 - 0.11 12.2 1.3 0.29 10.9 1.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3789) RNA_pol_Rpb1_5 PF04998.17 OAP56480.1 - 9.5e-85 284.2 0.4 2e-84 283.2 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 OAP56480.1 - 2.3e-68 229.6 0.2 5.2e-68 228.5 0.2 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 OAP56480.1 - 2.8e-36 124.8 0.1 2.1e-34 118.7 0.0 3.5 4 0 0 4 4 4 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.12 OAP56480.1 - 2.4e-25 89.5 1.2 4.5e-24 85.4 0.7 3.0 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.17 OAP56480.1 - 3.1e-18 65.7 0.0 1.3e-17 63.7 0.0 2.1 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 adh_short PF00106.25 OAP56482.1 - 1.8e-31 109.1 0.0 4e-31 108.0 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP56482.1 - 1e-27 97.2 0.0 1.4e-27 96.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP56482.1 - 0.003 17.5 0.0 0.0083 16.1 0.0 1.7 1 1 0 1 1 1 1 KR domain Sugar_tr PF00083.24 OAP56483.1 - 1.7e-87 294.2 19.7 1.9e-87 294.0 19.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP56483.1 - 7.1e-27 94.3 39.9 1.8e-20 73.2 18.4 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily GFO_IDH_MocA PF01408.22 OAP56485.1 - 3.1e-09 37.7 0.0 1.5e-08 35.5 0.0 2.0 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 OAP56485.1 - 0.01 15.9 0.0 0.024 14.7 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain PrpF PF04303.13 OAP56486.1 - 1.3e-85 287.6 0.0 1.7e-85 287.3 0.0 1.1 1 0 0 1 1 1 1 PrpF protein DLH PF01738.18 OAP56487.1 - 2.9e-32 112.0 0.0 4e-32 111.5 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 OAP56487.1 - 7.1e-05 22.8 0.0 0.00012 22.0 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OAP56487.1 - 0.019 14.4 0.0 0.067 12.7 0.0 1.8 2 0 0 2 2 2 0 Prolyl oligopeptidase family Ammonium_transp PF00909.21 OAP56488.1 - 1.3e-76 257.9 31.9 1.4e-76 257.8 31.9 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family zf-PARP PF00645.18 OAP56489.1 - 2.3e-20 73.2 0.1 7.8e-20 71.5 0.1 2.0 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Lactamase_B_2 PF12706.7 OAP56490.1 - 2.3e-29 102.4 0.1 6.9e-28 97.5 0.1 2.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 OAP56490.1 - 2.6e-10 40.4 0.0 8e-10 38.9 0.0 1.9 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 OAP56490.1 - 7.1e-05 22.9 0.1 0.006 16.6 0.0 2.4 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily BCS1_N PF08740.11 OAP56491.1 - 7.4e-46 156.5 0.5 1e-45 156.0 0.5 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 OAP56491.1 - 6.3e-19 68.7 0.0 1.1e-18 67.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OAP56491.1 - 8.8e-05 22.9 0.0 0.00021 21.8 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 OAP56491.1 - 0.00068 19.6 0.0 0.0022 18.0 0.0 1.8 1 1 1 2 2 2 1 AAA domain (dynein-related subfamily) DUF815 PF05673.13 OAP56491.1 - 0.0014 17.9 0.0 0.0021 17.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_25 PF13481.6 OAP56491.1 - 0.0026 17.4 0.0 0.016 14.8 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 OAP56491.1 - 0.0031 18.1 0.0 0.0062 17.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 OAP56491.1 - 0.0088 15.6 0.0 0.016 14.7 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_24 PF13479.6 OAP56491.1 - 0.015 15.1 0.0 0.051 13.3 0.0 1.8 1 1 0 2 2 2 0 AAA domain PPV_E1_C PF00519.17 OAP56491.1 - 0.015 14.2 0.0 0.022 13.6 0.0 1.1 1 0 0 1 1 1 0 Papillomavirus helicase RNA_helicase PF00910.22 OAP56491.1 - 0.016 15.6 0.0 0.03 14.7 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_21 PF13304.6 OAP56491.1 - 0.027 14.3 0.0 0.049 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran PF00005.27 OAP56491.1 - 0.034 14.7 0.0 0.063 13.8 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 OAP56491.1 - 0.035 13.9 0.0 0.078 12.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATPase PF06745.13 OAP56491.1 - 0.065 12.6 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_11 PF13086.6 OAP56491.1 - 0.071 12.9 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 OAP56491.1 - 0.12 12.6 0.0 0.26 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 OAP56491.1 - 0.13 12.5 0.0 0.29 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 OAP56491.1 - 0.15 12.3 0.0 0.36 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 OAP56491.1 - 0.19 11.8 0.0 0.36 10.9 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase Ank_2 PF12796.7 OAP56492.1 - 3.2e-12 46.9 0.1 5.3e-11 43.0 0.0 2.8 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAP56492.1 - 1.2e-10 41.7 0.1 1.4e-08 35.1 0.0 3.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OAP56492.1 - 2.6e-09 37.2 2.4 2.3e-05 24.6 0.0 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 OAP56492.1 - 8.7e-08 32.3 0.1 0.00022 21.5 0.0 3.6 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 OAP56492.1 - 5.1e-06 26.4 0.0 0.94 10.3 0.0 4.1 3 0 0 3 3 3 2 Ankyrin repeat NACHT PF05729.12 OAP56492.1 - 1.8e-05 24.7 0.2 6.6e-05 22.9 0.0 2.1 2 0 0 2 2 2 1 NACHT domain Helo_like_N PF17111.5 OAP56492.1 - 0.0003 20.2 0.1 0.00056 19.3 0.1 1.4 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins AAA_16 PF13191.6 OAP56492.1 - 0.0026 18.2 0.0 0.015 15.7 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 OAP56492.1 - 0.015 15.6 0.0 0.064 13.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 OAP56492.1 - 0.073 13.5 0.0 0.17 12.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Methyltr_RsmB-F PF01189.17 OAP56493.1 - 3.7e-33 114.9 0.0 4e-26 91.9 0.0 3.0 2 1 0 2 2 2 2 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 OAP56493.1 - 0.0013 18.8 0.0 0.0023 18.0 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Glyco_hydro_3_C PF01915.22 OAP56495.1 - 1.8e-59 201.2 0.0 3e-59 200.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 OAP56495.1 - 8.2e-51 173.3 0.0 1.3e-50 172.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 OAP56495.1 - 8.6e-24 83.4 0.2 1.9e-23 82.3 0.2 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 OAP56495.1 - 3e-14 53.0 0.0 5.6e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 PA14 domain Zn_clus PF00172.18 OAP56496.1 - 0.00081 19.5 10.8 0.002 18.2 10.8 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 OAP56497.1 - 5.3e-26 91.4 26.9 5.3e-26 91.4 26.9 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Abhydrolase_3 PF07859.13 OAP56498.1 - 4.2e-14 52.9 0.0 1e-12 48.4 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 OAP56498.1 - 1.8e-07 30.4 0.0 2.5e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase enzyme Peptidase_S9 PF00326.21 OAP56498.1 - 1.1e-05 25.0 0.0 0.0037 16.8 0.0 3.0 3 0 0 3 3 3 1 Prolyl oligopeptidase family COesterase PF00135.28 OAP56498.1 - 0.0085 15.0 0.5 0.012 14.5 0.0 1.4 2 0 0 2 2 2 1 Carboxylesterase family DLH PF01738.18 OAP56498.1 - 0.074 12.6 0.0 0.18 11.3 0.0 1.6 2 0 0 2 2 2 0 Dienelactone hydrolase family CDH-cyt PF16010.5 OAP56499.1 - 4.2e-18 65.7 2.9 8.8e-18 64.6 2.9 1.5 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase Cytochrom_B561 PF03188.16 OAP56499.1 - 2.2e-07 31.1 13.2 2.2e-07 31.1 13.2 2.1 3 0 0 3 3 3 1 Eukaryotic cytochrome b561 DUF2427 PF10348.9 OAP56499.1 - 1.5 8.6 16.8 0.07 12.9 9.7 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF2427) NAD_binding_10 PF13460.6 OAP56501.1 - 3.6e-08 33.5 0.0 5.1e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 OAP56501.1 - 0.0082 15.2 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 OAP56501.1 - 0.051 12.7 0.0 0.17 11.0 0.0 1.9 1 1 1 2 2 2 0 Male sterility protein RNA_pol_Rpb5_C PF01191.19 OAP56502.1 - 1.8e-29 101.4 0.1 3.7e-29 100.4 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 OAP56502.1 - 1.4e-24 86.5 0.0 2.2e-24 85.9 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.12 OAP56502.1 - 0.0012 18.9 0.0 0.0025 17.8 0.0 1.5 1 0 0 1 1 1 1 Restriction endonuclease Sof1 PF04158.14 OAP56502.1 - 0.12 12.6 0.0 0.26 11.6 0.0 1.5 1 0 0 1 1 1 0 Sof1-like domain adh_short PF00106.25 OAP56505.1 - 3.6e-31 108.2 0.0 4.7e-31 107.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP56505.1 - 6.6e-25 88.0 0.0 8.6e-25 87.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP56505.1 - 0.00015 21.8 0.1 0.00022 21.2 0.1 1.3 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 OAP56505.1 - 0.21 11.4 0.0 0.37 10.7 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PGM_PMM_I PF02878.16 OAP56507.1 - 5e-17 61.9 1.1 6.4e-09 35.6 0.0 3.1 2 1 1 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 OAP56507.1 - 2.5e-10 40.4 0.6 6.4e-10 39.1 0.6 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_II PF02879.16 OAP56507.1 - 0.003 18.1 0.9 0.095 13.3 0.2 3.5 3 1 0 3 3 3 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 OAP56507.1 - 0.01 16.0 0.1 0.023 14.9 0.1 1.6 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III Per1 PF04080.13 OAP56508.1 - 3.8e-107 357.8 12.0 4.6e-107 357.5 12.0 1.1 1 0 0 1 1 1 1 Per1-like family DIL PF01843.19 OAP56509.1 - 6.4e-32 109.9 0.5 1.6e-31 108.6 0.5 1.7 1 0 0 1 1 1 1 DIL domain Ank_2 PF12796.7 OAP56509.1 - 5.4e-14 52.6 0.0 1.5e-13 51.2 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAP56509.1 - 1.3e-10 41.6 0.4 3.5e-07 30.7 0.2 3.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 OAP56509.1 - 2.5e-10 40.3 0.1 4.8e-05 23.6 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 OAP56509.1 - 1.1e-09 38.4 0.0 3.9e-06 27.0 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAP56509.1 - 1.9e-07 30.8 1.3 0.00043 20.5 0.0 4.0 4 0 0 4 4 4 1 Ankyrin repeat C1ORF64 PF15547.6 OAP56509.1 - 0.18 12.3 0.7 0.5 10.8 0.7 1.8 1 0 0 1 1 1 0 Steroid receptor-associated and regulated protein Podoplanin PF05808.11 OAP56510.1 - 0.002 18.2 2.3 0.002 18.2 2.3 2.3 2 0 0 2 2 2 1 Podoplanin MGC-24 PF05283.11 OAP56510.1 - 0.014 15.9 6.7 0.014 15.9 6.7 2.5 2 1 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Amnionless PF14828.6 OAP56510.1 - 0.055 12.3 0.6 0.081 11.7 0.6 1.3 1 0 0 1 1 1 0 Amnionless RIFIN PF02009.16 OAP56510.1 - 0.14 12.0 2.2 0.1 12.5 0.7 1.5 1 1 0 1 1 1 0 Rifin DUF4690 PF15756.5 OAP56510.1 - 1.4 9.6 12.0 0.19 12.4 3.3 2.6 2 0 0 2 2 2 0 Small Novel Rich in Cartilage UCH PF00443.29 OAP56511.1 - 7.4e-22 78.1 0.0 5.5e-21 75.2 0.0 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase CENP-B_dimeris PF09026.10 OAP56511.1 - 3.7 8.0 26.2 0.21 12.0 14.3 3.3 3 0 0 3 3 3 0 Centromere protein B dimerisation domain RXT2_N PF08595.11 OAP56511.1 - 9.5 6.2 19.1 0.76 9.8 7.7 3.6 3 0 0 3 3 3 0 RXT2-like, N-terminal Cir_N PF10197.9 OAP56512.1 - 0.00043 20.4 5.3 0.00043 20.4 5.3 3.2 2 1 0 2 2 2 1 N-terminal domain of CBF1 interacting co-repressor CIR DMRT-like PF15791.5 OAP56512.1 - 0.15 12.5 0.2 0.31 11.5 0.2 1.6 1 0 0 1 1 1 0 Doublesex-and mab-3-related transcription factor C1 and C2 AAA PF00004.29 OAP56513.1 - 5.8e-51 172.4 0.0 7.7e-38 129.9 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OAP56513.1 - 3e-09 36.5 0.1 6.6e-09 35.4 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 OAP56513.1 - 4e-09 37.1 0.1 0.0011 19.3 0.0 2.9 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 OAP56513.1 - 4e-09 36.9 0.2 0.00014 22.2 0.0 3.4 2 2 0 3 3 3 2 AAA domain CDC48_2 PF02933.17 OAP56513.1 - 6.6e-09 35.4 0.4 1e-07 31.6 0.1 2.4 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_5 PF07728.14 OAP56513.1 - 7.8e-09 35.6 0.0 0.002 18.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 OAP56513.1 - 4.3e-08 33.2 0.0 0.0011 19.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 OAP56513.1 - 5.4e-08 33.2 0.0 0.01 16.2 0.0 2.7 2 0 0 2 2 2 2 RNA helicase RuvB_N PF05496.12 OAP56513.1 - 1.8e-07 31.0 0.0 0.031 14.0 0.0 2.8 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain NB-ARC PF00931.22 OAP56513.1 - 2.9e-07 29.9 0.0 0.033 13.4 0.0 3.2 3 0 0 3 3 3 2 NB-ARC domain AAA_18 PF13238.6 OAP56513.1 - 4.9e-07 30.4 0.0 0.016 15.8 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_33 PF13671.6 OAP56513.1 - 9e-07 29.1 0.0 0.035 14.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 OAP56513.1 - 9.3e-07 28.4 0.1 0.0054 16.1 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI NACHT PF05729.12 OAP56513.1 - 9.9e-07 28.8 1.1 0.016 15.1 0.0 3.6 4 0 0 4 4 3 1 NACHT domain TIP49 PF06068.13 OAP56513.1 - 2.9e-06 26.7 0.0 0.016 14.5 0.0 2.4 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_2 PF07724.14 OAP56513.1 - 4.4e-06 26.9 0.0 5e-05 23.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_28 PF13521.6 OAP56513.1 - 8.6e-06 26.1 0.0 0.15 12.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 OAP56513.1 - 9.5e-06 25.5 0.0 0.011 15.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 OAP56513.1 - 2.6e-05 24.0 0.0 0.1 12.3 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein TsaE PF02367.17 OAP56513.1 - 9.1e-05 22.5 0.0 0.19 11.8 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 OAP56513.1 - 9.9e-05 22.9 0.3 0.046 14.2 0.1 2.7 3 0 0 3 3 2 1 ABC transporter CDC48_N PF02359.18 OAP56513.1 - 0.00016 21.8 0.0 0.00037 20.6 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_7 PF12775.7 OAP56513.1 - 0.00021 20.9 0.2 0.026 14.1 0.0 2.6 3 0 0 3 3 2 1 P-loop containing dynein motor region PhoH PF02562.16 OAP56513.1 - 0.00032 20.2 0.0 0.45 9.9 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein ATPase PF06745.13 OAP56513.1 - 0.00034 20.0 0.4 0.036 13.4 0.1 2.6 2 1 1 3 3 3 1 KaiC AAA_25 PF13481.6 OAP56513.1 - 0.00065 19.3 0.2 2 8.0 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_11 PF13086.6 OAP56513.1 - 0.00072 19.4 0.0 0.56 10.0 0.0 2.2 2 0 0 2 2 2 2 AAA domain ATPase_2 PF01637.18 OAP56513.1 - 0.00079 19.4 0.3 5.6 6.8 0.0 3.3 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea AAA_17 PF13207.6 OAP56513.1 - 0.00081 19.8 0.3 0.42 11.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain Parvo_NS1 PF01057.17 OAP56513.1 - 0.0011 18.1 0.0 0.48 9.5 0.0 2.3 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.26 OAP56513.1 - 0.0041 16.9 0.0 0.66 9.7 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain Rad17 PF03215.15 OAP56513.1 - 0.0042 17.0 0.0 4 7.3 0.0 2.7 3 0 0 3 3 2 1 Rad17 P-loop domain AAA_30 PF13604.6 OAP56513.1 - 0.0047 16.7 0.0 0.41 10.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain TniB PF05621.11 OAP56513.1 - 0.0049 16.3 0.1 4.3 6.7 0.0 3.8 3 1 0 3 3 3 0 Bacterial TniB protein AAA_19 PF13245.6 OAP56513.1 - 0.0052 17.1 0.3 0.67 10.3 0.0 2.9 3 0 0 3 3 2 1 AAA domain Vps4_C PF09336.10 OAP56513.1 - 0.012 15.6 0.2 0.81 9.7 0.0 3.3 3 0 0 3 3 3 0 Vps4 C terminal oligomerisation domain DUF2075 PF09848.9 OAP56513.1 - 0.014 14.7 0.0 1.2 8.3 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 OAP56513.1 - 0.015 15.3 0.0 4.6 7.2 0.1 2.6 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 OAP56513.1 - 0.016 15.0 0.0 0.14 11.8 0.0 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_3 PF07726.11 OAP56513.1 - 0.019 14.8 0.0 0.54 10.1 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 OAP56513.1 - 0.029 14.3 0.1 13 5.7 0.0 2.9 3 0 0 3 3 2 0 NTPase Zeta_toxin PF06414.12 OAP56513.1 - 0.046 13.0 0.0 3.8 6.8 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin Glyoxalase PF00903.25 OAP56514.1 - 4.5e-12 46.3 0.0 3.1e-11 43.5 0.0 2.1 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 OAP56514.1 - 0.00062 20.0 0.0 0.0021 18.3 0.0 2.0 2 1 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyco_hydro_67M PF07488.12 OAP56515.1 - 1.1e-140 468.3 0.1 1.7e-140 467.7 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 middle domain Glyco_hydro_67C PF07477.12 OAP56515.1 - 6.5e-88 294.0 3.6 9.4e-88 293.5 3.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 C-terminus Glyco_hydro_67N PF03648.14 OAP56515.1 - 1.5e-24 86.6 0.0 3.1e-24 85.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 N-terminus Glyco_hydro_20b PF02838.15 OAP56515.1 - 0.0036 18.1 0.1 0.013 16.2 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 20, domain 2 Avidin PF01382.17 OAP56515.1 - 8.5 6.9 10.8 0.35 11.3 0.1 3.0 3 0 0 3 3 3 0 Avidin family F-box-like PF12937.7 OAP56516.1 - 0.03 14.2 0.0 0.085 12.8 0.0 1.8 1 0 0 1 1 1 0 F-box-like MFS_1 PF07690.16 OAP56517.1 - 3.2e-36 125.0 24.7 7.3e-36 123.8 24.4 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAP56518.1 - 3.1e-78 263.7 19.5 4.4e-78 263.2 19.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter DUF3589 PF12141.8 OAP56518.1 - 1.4e-71 241.6 0.0 1.6e-69 234.8 0.0 2.2 1 1 0 1 1 1 1 Beta-mannosyltransferases MFS_1 PF07690.16 OAP56518.1 - 6.9e-11 41.7 48.6 1.1e-10 40.9 25.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MaoC_dehydratas PF01575.19 OAP56519.1 - 4.9e-23 81.0 0.0 9.2e-23 80.1 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 OAP56519.1 - 0.00024 21.3 0.0 0.0027 17.8 0.0 2.1 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase Methyltransf_25 PF13649.6 OAP56520.1 - 2.3e-11 44.2 0.0 5.8e-11 43.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAP56520.1 - 8.8e-11 41.8 0.0 1.5e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 OAP56520.1 - 1.1e-10 41.4 0.1 1.7e-10 40.8 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 OAP56520.1 - 3.3e-08 33.6 0.0 5e-07 29.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAP56520.1 - 8.5e-08 32.7 0.0 3.1e-07 31.0 0.0 1.9 2 1 1 3 3 2 1 Methyltransferase domain Methyltransf_9 PF08003.11 OAP56520.1 - 9.4e-06 24.8 0.1 1.4e-05 24.2 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_12 PF08242.12 OAP56520.1 - 9.5e-05 23.1 0.0 0.00021 22.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OAP56520.1 - 0.00034 20.2 0.1 0.00057 19.5 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.7 OAP56520.1 - 0.0011 18.9 0.1 0.0021 18.0 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 OAP56520.1 - 0.0012 18.2 0.0 0.0021 17.4 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_16 PF10294.9 OAP56520.1 - 0.0017 18.1 0.1 0.0029 17.4 0.1 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_32 PF13679.6 OAP56520.1 - 0.008 16.2 0.0 0.018 15.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 OAP56520.1 - 0.033 13.6 0.0 0.059 12.8 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB PCMT PF01135.19 OAP56520.1 - 0.039 13.7 0.1 0.074 12.8 0.1 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PRMT5 PF05185.16 OAP56520.1 - 0.039 13.8 0.1 0.068 13.0 0.1 1.4 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Methyltransf_24 PF13578.6 OAP56520.1 - 0.043 14.8 0.0 0.11 13.5 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.15 OAP56520.1 - 0.099 12.3 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 MFS_1 PF07690.16 OAP56521.1 - 1.3e-30 106.6 24.9 1.3e-30 106.6 24.9 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Transgly_assoc PF04226.13 OAP56521.1 - 0.029 14.6 0.8 0.11 12.7 0.8 2.0 1 0 0 1 1 1 0 Transglycosylase associated protein DUF308 PF03729.13 OAP56521.1 - 0.39 11.1 7.9 2.9 8.3 4.0 3.0 2 0 0 2 2 2 0 Short repeat of unknown function (DUF308) Saf_2TM PF18303.1 OAP56521.1 - 0.54 9.8 0.0 0.54 9.8 0.0 2.9 3 0 0 3 3 3 0 SAVED-fused 2TM effector domain RasGEF PF00617.19 OAP56522.1 - 3e-42 144.8 0.0 4.8e-42 144.2 0.0 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 OAP56522.1 - 4.5e-12 46.1 0.3 1.1e-11 44.9 0.3 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif AA_permease PF00324.21 OAP56523.1 - 1.4e-147 492.2 36.1 1.6e-147 492.0 36.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAP56523.1 - 1e-35 123.4 38.2 1.3e-35 123.1 38.2 1.1 1 0 0 1 1 1 1 Amino acid permease DUF4781 PF16013.5 OAP56523.1 - 0.049 12.4 1.7 0.066 12.0 0.8 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4781) Internalin_N PF12354.8 OAP56523.1 - 0.44 10.7 1.9 2.1 8.5 0.0 3.1 2 0 0 2 2 2 0 Bacterial adhesion/invasion protein N terminal Dynamin_N PF00350.23 OAP56524.1 - 7e-36 123.8 0.0 1.5e-35 122.7 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 OAP56524.1 - 3.2e-20 72.5 0.0 6.1e-20 71.6 0.0 1.5 1 0 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.23 OAP56524.1 - 2.3e-05 24.4 0.0 0.00015 21.8 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase GED PF02212.18 OAP56524.1 - 4.8e-05 23.4 1.7 0.0005 20.2 0.0 3.1 3 1 0 3 3 3 1 Dynamin GTPase effector domain AAA_21 PF13304.6 OAP56524.1 - 0.019 14.8 0.0 0.034 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AviRa PF11599.8 OAP56524.1 - 0.035 13.6 0.0 0.075 12.5 0.0 1.5 1 0 0 1 1 1 0 RRNA methyltransferase AviRa AAA_15 PF13175.6 OAP56524.1 - 0.047 13.4 0.0 0.082 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain FeoB_N PF02421.18 OAP56524.1 - 0.048 13.2 0.0 4 6.9 0.0 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_29 PF13555.6 OAP56524.1 - 0.084 12.6 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain zf-primase PF09329.11 OAP56525.1 - 7.2e-18 64.1 0.7 1.3e-17 63.3 0.7 1.5 1 0 0 1 1 1 1 Primase zinc finger tRNA_anti-codon PF01336.25 OAP56525.1 - 0.095 12.7 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain TMEM171 PF15471.6 OAP56525.1 - 0.26 10.3 1.0 0.55 9.2 1.0 1.5 1 0 0 1 1 1 0 Transmembrane protein family 171 RNase_H2-Ydr279 PF09468.10 OAP56526.1 - 5.7e-33 114.4 1.6 6.7e-33 114.1 0.0 1.9 2 1 0 2 2 2 1 Ydr279p protein family (RNase H2 complex component) wHTH domain Ydr279_N PF17745.1 OAP56526.1 - 1.7e-19 69.8 0.0 8e-19 67.7 0.0 2.2 2 0 0 2 2 2 1 Ydr279p protein triple barrel domain DRY_EERY PF09750.9 OAP56526.1 - 0.6 10.4 3.3 1.1 9.5 3.3 1.4 1 0 0 1 1 1 0 Alternative splicing regulator ABC2_membrane PF01061.24 OAP56527.1 - 1.7e-80 269.4 56.3 8.5e-44 149.5 21.1 3.0 4 0 0 4 4 3 2 ABC-2 type transporter PDR_CDR PF06422.12 OAP56527.1 - 2.1e-37 126.9 2.3 2e-29 101.3 0.1 2.9 2 0 0 2 2 2 2 CDR ABC transporter ABC_tran PF00005.27 OAP56527.1 - 4e-35 121.3 0.0 2.7e-16 60.3 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_trans_N PF14510.6 OAP56527.1 - 8.9e-12 45.5 2.5 3.2e-11 43.7 2.4 2.0 1 1 0 1 1 1 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 OAP56527.1 - 2.3e-08 33.5 53.0 1.4e-07 31.0 18.5 2.8 2 1 0 2 2 2 2 ABC-2 family transporter protein RsgA_GTPase PF03193.16 OAP56527.1 - 1.3e-06 28.4 0.0 9.5e-06 25.6 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 OAP56527.1 - 6.7e-06 26.6 0.2 0.0026 18.2 0.0 2.9 3 0 0 3 3 2 1 AAA ATPase domain AAA_21 PF13304.6 OAP56527.1 - 1.6e-05 24.9 0.0 0.067 13.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 OAP56527.1 - 4.2e-05 23.2 0.1 0.0018 17.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 OAP56527.1 - 6.5e-05 22.6 0.0 0.023 14.5 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.6 OAP56527.1 - 0.00044 20.5 0.2 0.12 12.6 0.1 2.8 2 1 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 OAP56527.1 - 0.0005 20.1 0.0 0.21 11.7 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_23 PF13476.6 OAP56527.1 - 0.0021 18.6 0.7 0.038 14.5 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_28 PF13521.6 OAP56527.1 - 0.0031 17.8 0.1 0.0031 17.8 0.1 2.2 3 0 0 3 3 1 1 AAA domain dNK PF01712.19 OAP56527.1 - 0.0034 17.3 0.0 0.014 15.3 0.0 1.9 2 0 0 2 2 2 1 Deoxynucleoside kinase AAA_18 PF13238.6 OAP56527.1 - 0.0037 17.8 0.0 0.029 14.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 OAP56527.1 - 0.0043 16.7 0.1 0.42 10.2 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain T2SSE PF00437.20 OAP56527.1 - 0.0046 16.0 0.0 0.75 8.8 0.1 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_30 PF13604.6 OAP56527.1 - 0.006 16.3 0.1 0.068 12.9 0.1 2.2 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 OAP56527.1 - 0.0061 16.5 0.0 0.15 11.9 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_33 PF13671.6 OAP56527.1 - 0.01 16.0 0.1 0.81 9.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 OAP56527.1 - 0.032 13.7 0.0 5.6 6.3 0.0 2.9 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain TsaE PF02367.17 OAP56527.1 - 0.055 13.5 0.1 0.23 11.5 0.1 1.9 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE FtsK_SpoIIIE PF01580.18 OAP56527.1 - 0.077 12.3 0.9 12 5.2 0.1 2.7 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_17 PF13207.6 OAP56527.1 - 0.095 13.1 0.1 0.69 10.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 OAP56527.1 - 0.15 11.8 0.0 0.66 9.7 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein Septin PF00735.18 OAP56527.1 - 0.16 11.2 0.1 11 5.3 0.0 2.2 2 0 0 2 2 2 0 Septin AAA PF00004.29 OAP56527.1 - 0.18 12.2 0.1 2.7 8.4 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MRP-S26 PF14943.6 OAP56527.1 - 5.4 6.9 6.9 0.71 9.8 0.5 2.4 2 1 0 2 2 2 0 Mitochondrial ribosome subunit S26 Ribonuclease_3 PF00636.26 OAP56530.1 - 6.8e-16 58.8 0.0 3.3e-15 56.6 0.0 2.2 1 1 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 OAP56530.1 - 2.3e-12 47.2 0.0 4e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.26 OAP56530.1 - 0.012 16.3 0.6 0.026 15.2 0.6 1.7 1 1 0 1 1 1 0 Double-stranded RNA binding motif MRP-S33 PF08293.11 OAP56531.1 - 4.2e-28 97.4 0.0 5.9e-28 96.9 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 adh_short_C2 PF13561.6 OAP56532.1 - 3.9e-62 209.9 0.8 4.5e-62 209.7 0.8 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP56532.1 - 1.5e-47 161.6 1.9 1.9e-47 161.3 1.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAP56532.1 - 1e-05 25.5 0.2 1.6e-05 24.9 0.2 1.3 1 0 0 1 1 1 1 KR domain LppA PF16708.5 OAP56532.1 - 0.03 14.2 0.3 3 7.7 0.0 2.8 2 2 0 2 2 2 0 Lipoprotein confined to pathogenic Mycobacterium DUF382 PF04037.13 OAP56533.1 - 4.9e-59 198.0 0.9 1.1e-58 196.9 0.9 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF382) PSP PF04046.16 OAP56533.1 - 2.7e-21 75.1 4.8 6.3e-21 74.0 4.8 1.7 1 0 0 1 1 1 1 PSP DUF1192 PF06698.11 OAP56533.1 - 0.013 15.6 10.0 1.3 9.1 5.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Keratin_2_tail PF16210.5 OAP56533.1 - 0.055 13.7 25.3 0.028 14.7 22.4 1.9 1 1 0 1 1 1 0 Keratin type II cytoskeletal 1 tail TFIIB PF00382.19 OAP56534.1 - 5e-27 93.7 0.1 3.9e-13 49.2 0.0 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 OAP56534.1 - 9.6e-10 37.8 0.5 1.7e-09 37.1 0.5 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.23 OAP56534.1 - 1e-05 25.2 0.2 2.1e-05 24.2 0.2 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 OAP56534.1 - 0.00039 20.5 0.0 1.2 9.2 0.0 2.4 2 0 0 2 2 2 2 Cyclin, C-terminal domain Sigma70_r4_2 PF08281.12 OAP56534.1 - 0.034 13.8 0.0 0.092 12.4 0.0 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 GerE PF00196.19 OAP56534.1 - 0.057 13.0 0.1 0.16 11.5 0.0 1.8 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family zf-ribbon_3 PF13248.6 OAP56534.1 - 0.12 11.8 4.7 1.2 8.6 4.7 2.2 1 1 0 1 1 1 0 zinc-ribbon domain ATP_sub_h PF10775.9 OAP56535.1 - 5.1e-25 87.2 1.5 7e-25 86.8 1.5 1.2 1 0 0 1 1 1 1 ATP synthase complex subunit h AMP-binding PF00501.28 OAP56536.1 - 1.5e-92 310.4 0.0 2.1e-92 309.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme DUF1765 PF08578.10 OAP56536.1 - 3.7e-42 143.7 7.3 5.9e-42 143.1 6.3 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1765) AMP-binding_C PF13193.6 OAP56536.1 - 2.3e-13 50.9 0.0 4.6e-13 49.9 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Reticulon PF02453.17 OAP56537.1 - 1.7e-28 99.6 2.5 2.4e-28 99.0 2.5 1.2 1 0 0 1 1 1 1 Reticulon PDZ_1 PF12812.7 OAP56538.1 - 1.6e-53 178.6 0.0 6.9e-35 118.9 0.0 2.8 2 0 0 2 2 2 2 PDZ-like domain Trypsin_2 PF13365.6 OAP56538.1 - 2e-23 84.0 2.1 3.6e-21 76.6 0.1 2.6 2 0 0 2 2 2 2 Trypsin-like peptidase domain PDZ_6 PF17820.1 OAP56538.1 - 2.2e-15 56.2 0.3 1.4e-07 31.3 0.0 3.7 3 0 0 3 3 3 3 PDZ domain PDZ_2 PF13180.6 OAP56538.1 - 1.3e-14 54.3 0.1 1.6e-05 25.1 0.0 3.7 3 0 0 3 3 3 3 PDZ domain PDZ PF00595.24 OAP56538.1 - 2.6e-11 43.7 0.0 7.8e-06 26.2 0.0 3.6 3 0 0 3 3 3 2 PDZ domain Trypsin PF00089.26 OAP56538.1 - 5.6e-06 26.3 0.2 2.7e-05 24.1 0.1 2.2 2 1 0 2 2 2 1 Trypsin Peptidase_S46 PF10459.9 OAP56538.1 - 0.0045 15.7 0.9 0.007 15.1 0.1 1.6 2 0 0 2 2 2 1 Peptidase S46 Tricorn_PDZ PF14685.6 OAP56538.1 - 0.0072 16.3 0.1 0.39 10.7 0.1 3.1 3 0 0 3 3 3 1 Tricorn protease PDZ domain 4HPAD_g_N PF18671.1 OAP56538.1 - 0.11 12.2 0.0 0.37 10.5 0.0 1.9 1 0 0 1 1 1 0 4-Hydroxyphenylacetate decarboxylase subunit gamma N-terminal Ank_2 PF12796.7 OAP56539.1 - 1.5e-21 76.8 0.0 4.9e-12 46.3 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OAP56539.1 - 7.9e-17 61.1 0.5 7.5e-08 32.5 0.0 4.3 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAP56539.1 - 1.3e-16 59.0 0.2 0.00011 22.4 0.0 5.8 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 OAP56539.1 - 5.4e-16 58.2 0.0 0.00063 20.1 0.0 5.0 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 OAP56539.1 - 7e-16 58.4 1.7 2.7e-09 37.4 0.1 3.9 2 1 2 4 4 4 3 Ankyrin repeats (many copies) PNP_UDP_1 PF01048.20 OAP56539.1 - 6.6e-10 38.6 0.0 1.2e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 Phosphorylase superfamily NACHT PF05729.12 OAP56539.1 - 1e-08 35.3 0.1 2.5e-08 34.0 0.1 1.8 1 0 0 1 1 1 1 NACHT domain KAP_NTPase PF07693.14 OAP56539.1 - 0.0019 17.5 0.0 0.0034 16.7 0.0 1.3 1 0 0 1 1 1 1 KAP family P-loop domain AAA_19 PF13245.6 OAP56539.1 - 0.04 14.2 0.0 0.14 12.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 OAP56539.1 - 0.082 12.3 0.0 0.23 10.8 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 OAP56539.1 - 0.16 12.0 0.0 15 5.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Ank_2 PF12796.7 OAP56540.1 - 6.4e-59 196.5 3.5 4.3e-18 65.7 0.0 5.4 2 1 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAP56540.1 - 1.5e-49 165.8 10.6 5.2e-14 52.4 0.0 9.0 5 3 4 9 9 9 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAP56540.1 - 3.7e-44 143.6 9.4 8.1e-05 22.7 0.0 11.3 11 0 0 11 11 11 10 Ankyrin repeat Ank PF00023.30 OAP56540.1 - 2.5e-39 132.0 14.8 6.9e-06 26.3 0.0 10.0 10 0 0 10 10 10 7 Ankyrin repeat Ank_5 PF13857.6 OAP56540.1 - 1.1e-36 124.4 9.5 1.4e-09 38.0 0.0 8.7 4 3 5 9 9 9 8 Ankyrin repeats (many copies) zf-C2H2_4 PF13894.6 OAP56540.1 - 4 8.5 4.6 1.1e+02 4.1 0.1 4.1 4 0 0 4 4 4 0 C2H2-type zinc finger Peptidase_S8 PF00082.22 OAP56542.1 - 1.6e-21 76.8 0.1 3.8e-21 75.6 0.1 1.5 1 1 0 1 1 1 1 Subtilase family SSXT PF05030.12 OAP56543.1 - 3.1e-05 23.5 7.2 0.03 13.9 0.0 3.1 3 0 0 3 3 3 2 SSXT protein (N-terminal region) FUSC PF04632.12 OAP56543.1 - 0.57 8.6 8.7 0.94 7.9 8.7 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Cdh1_DBD_1 PF18196.1 OAP56543.1 - 0.65 10.3 2.3 1.5 9.1 2.3 1.6 1 0 0 1 1 1 0 Chromodomain helicase DNA-binding domain 1 TERB2 PF15101.6 OAP56543.1 - 2.7 8.0 8.8 6.1 6.8 8.8 1.6 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Presenilin PF01080.17 OAP56543.1 - 3.2 6.4 7.4 3.7 6.2 7.4 1.3 1 0 0 1 1 1 0 Presenilin Plasmodium_Vir PF05795.11 OAP56543.1 - 3.5 7.0 5.6 4.5 6.6 5.6 1.4 1 0 0 1 1 1 0 Plasmodium vivax Vir protein TPR_1 PF00515.28 OAP56544.1 - 0.0042 16.8 4.9 3 7.8 0.0 4.5 3 1 1 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 OAP56544.1 - 0.011 15.9 0.7 0.04 14.1 0.7 2.0 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 OAP56544.1 - 0.043 13.9 12.8 0.17 12.0 0.0 4.8 4 1 1 5 5 5 0 Tetratricopeptide repeat DUF2681 PF10883.8 OAP56544.1 - 0.058 13.8 3.8 0.72 10.3 0.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) Meis_PKNOX_N PF16493.5 OAP56544.1 - 0.12 12.7 0.2 1.6 9.1 0.2 2.5 2 0 0 2 2 2 0 N-terminal of Homeobox Meis and PKNOX1 Drf_DAD PF06345.11 OAP56544.1 - 0.34 11.0 1.0 5.7 7.2 0.1 3.2 2 0 0 2 2 2 0 DRF Autoregulatory Domain TPR_14 PF13428.6 OAP56544.1 - 0.69 10.9 5.1 0.76 10.8 0.2 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat DUF1993 PF09351.10 OAP56544.1 - 1.6 8.9 3.5 27 4.8 0.1 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF1993) Acyl-CoA_dh_1 PF00441.24 OAP56545.1 - 2.2e-31 109.1 1.7 3.6e-31 108.4 1.7 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 OAP56545.1 - 1.5e-20 73.2 0.0 2.5e-20 72.5 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 OAP56545.1 - 9.3e-20 71.4 0.2 2e-19 70.3 0.2 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 OAP56545.1 - 1.8e-15 57.4 1.1 3.8e-15 56.3 1.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain INCENP_ARK-bind PF03941.15 OAP56546.1 - 1.3e-17 63.5 0.7 1.3e-17 63.5 0.7 3.1 2 0 0 2 2 2 1 Inner centromere protein, ARK binding region DUF5401 PF17380.2 OAP56546.1 - 0.0019 16.4 29.0 0.0019 16.4 29.0 2.5 2 0 0 2 2 2 2 Family of unknown function (DUF5401) UQ_con PF00179.26 OAP56547.1 - 1.6e-42 144.5 0.0 1.8e-42 144.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OAP56547.1 - 0.085 12.6 0.0 0.18 11.5 0.0 1.5 1 1 0 1 1 1 0 Prokaryotic E2 family B 7tm_1 PF00001.21 OAP56548.1 - 0.0023 17.3 0.0 0.0051 16.2 0.0 1.7 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) HSNSD PF12062.8 OAP56548.1 - 0.15 10.7 0.0 0.22 10.2 0.0 1.1 1 0 0 1 1 1 0 heparan sulfate-N-deacetylase Mito_carr PF00153.27 OAP56549.1 - 5.7e-60 199.3 5.2 8.1e-20 70.5 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Clat_adaptor_s PF01217.20 OAP56550.1 - 7e-51 171.9 4.1 5.1e-50 169.1 4.1 1.8 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Ist1 PF03398.14 OAP56551.1 - 8.3e-53 178.7 0.4 1e-52 178.3 0.4 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Seryl_tRNA_N PF02403.22 OAP56552.1 - 0.37 11.0 1.9 0.29 11.4 0.3 1.6 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain CDC45 PF02724.14 OAP56552.1 - 0.5 8.6 8.1 0.72 8.1 8.1 1.1 1 0 0 1 1 1 0 CDC45-like protein SUN PF03856.13 OAP56553.1 - 1e-77 261.0 13.8 1e-77 261.0 13.8 1.8 2 0 0 2 2 2 1 Beta-glucosidase (SUN family) LCM PF04072.14 OAP56554.1 - 1.1e-22 80.9 0.0 4.1e-22 79.0 0.0 1.9 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase zf-RING_2 PF13639.6 OAP56555.1 - 5.3e-08 33.1 7.4 1.9e-07 31.3 7.4 2.0 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.8 OAP56555.1 - 0.00027 21.0 4.5 0.00077 19.6 4.5 1.8 1 0 0 1 1 1 1 FANCL C-terminal domain zf-rbx1 PF12678.7 OAP56555.1 - 0.00029 21.1 6.3 0.00029 21.1 6.3 2.0 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 OAP56555.1 - 0.00029 20.8 3.4 0.0004 20.4 2.1 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 OAP56555.1 - 0.0052 16.6 6.2 0.014 15.2 6.2 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAP56555.1 - 0.011 15.5 7.2 0.026 14.4 7.2 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Mad3_BUB1_I PF08311.12 OAP56555.1 - 0.019 15.0 1.1 0.046 13.7 0.5 2.0 2 0 0 2 2 1 0 Mad3/BUB1 homology region 1 RWD PF05773.22 OAP56555.1 - 0.049 13.9 0.0 0.2 12.0 0.0 2.1 1 0 0 1 1 1 0 RWD domain Zn_ribbon_17 PF17120.5 OAP56555.1 - 0.09 12.4 4.0 0.21 11.2 4.0 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type RINGv PF12906.7 OAP56555.1 - 0.2 11.8 6.2 0.59 10.3 6.2 1.9 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_3 PF13920.6 OAP56555.1 - 0.8 9.6 4.0 2.2 8.2 4.0 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 OAP56555.1 - 0.94 9.3 5.1 11 5.9 0.6 2.6 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain PHD PF00628.29 OAP56555.1 - 1 9.3 5.1 3 7.8 5.1 1.9 1 0 0 1 1 1 0 PHD-finger C1_1 PF00130.22 OAP56555.1 - 1.2 9.0 4.4 0.76 9.7 2.2 1.7 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_4 PF14447.6 OAP56555.1 - 4.3 7.3 6.2 12 5.9 6.2 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 DEAD_2 PF06733.15 OAP56556.1 - 1.1e-56 191.2 0.1 2e-56 190.4 0.1 1.5 1 0 0 1 1 1 1 DEAD_2 HBB PF06777.11 OAP56556.1 - 2.1e-47 161.3 2.9 4.6e-43 147.1 0.8 2.4 2 0 0 2 2 2 2 Helical and beta-bridge domain Helicase_C_2 PF13307.6 OAP56556.1 - 7.9e-43 146.6 0.0 2.4e-42 145.0 0.0 1.9 2 0 0 2 2 2 1 Helicase C-terminal domain ResIII PF04851.15 OAP56556.1 - 0.00021 21.3 0.0 0.013 15.5 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 OAP56556.1 - 0.003 17.4 0.0 0.33 10.7 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase SNF2_N PF00176.23 OAP56556.1 - 0.015 14.0 0.0 0.2 10.3 0.0 2.2 1 1 0 1 1 1 0 SNF2 family N-terminal domain DUF2075 PF09848.9 OAP56556.1 - 0.036 13.3 0.0 2.9 7.0 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 OAP56556.1 - 0.05 13.9 1.0 7.2 6.9 0.0 3.2 2 1 1 3 3 3 0 AAA domain Remorin_C PF03763.13 OAP56556.1 - 0.4 10.6 3.6 1.1 9.1 3.6 1.7 1 0 0 1 1 1 0 Remorin, C-terminal region PhyH PF05721.13 OAP56557.1 - 3.5e-17 63.4 0.0 1.7e-16 61.1 0.0 1.9 2 0 0 2 2 2 1 Phytanoyl-CoA dioxygenase (PhyH) Fungal_trans_2 PF11951.8 OAP56557.1 - 4.3e-07 29.1 0.5 6.7e-07 28.4 0.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sugar_tr PF00083.24 OAP56558.1 - 3.5e-98 329.4 23.5 4.4e-98 329.1 23.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP56558.1 - 3.5e-20 72.2 28.5 3.5e-20 72.2 28.5 2.5 1 1 2 3 3 3 2 Major Facilitator Superfamily Fungal_trans_2 PF11951.8 OAP56558.1 - 6.1e-09 35.2 0.1 1e-08 34.4 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain OATP PF03137.20 OAP56558.1 - 0.091 11.0 4.6 0.08 11.2 0.7 2.4 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Phage_holin_3_2 PF04550.12 OAP56558.1 - 0.23 12.0 1.3 0.96 10.0 1.3 2.1 1 0 0 1 1 1 0 Phage holin family 2 DUF2530 PF10745.9 OAP56558.1 - 9.7 6.5 10.2 7.3 6.9 3.7 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) PhyH PF05721.13 OAP56559.1 - 2.4e-12 47.6 0.0 3.6e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 OAP56559.1 - 0.18 12.2 0.0 0.33 11.4 0.0 1.5 1 1 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase OCD_Mu_crystall PF02423.15 OAP56560.1 - 4.4e-12 45.6 0.0 8.4e-12 44.6 0.0 1.5 1 1 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.20 OAP56560.1 - 4.2e-06 26.9 0.0 2e-05 24.6 0.0 2.1 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DUF3739 PF12545.8 OAP56560.1 - 0.0015 19.0 0.1 0.015 15.7 0.0 2.1 2 0 0 2 2 2 1 Filamentous haemagglutinin family outer membrane protein TruB_C PF09142.11 OAP56560.1 - 0.0058 16.4 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 tRNA Pseudouridine synthase II, C terminal NAD_binding_7 PF13241.6 OAP56560.1 - 0.021 15.2 0.0 0.041 14.3 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding F420_oxidored PF03807.17 OAP56560.1 - 0.024 15.2 0.0 0.062 13.9 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA PF01408.22 OAP56560.1 - 0.035 14.9 0.0 0.26 12.1 0.0 2.1 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold NAD_Gly3P_dh_N PF01210.23 OAP56560.1 - 0.088 12.8 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus PGA_cap PF09587.10 OAP56561.1 - 5.4e-63 212.8 0.0 9.2e-63 212.1 0.0 1.4 1 1 0 1 1 1 1 Bacterial capsule synthesis protein PGA_cap Aa_trans PF01490.18 OAP56563.1 - 5.6e-81 272.3 23.6 7.5e-81 271.9 23.6 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF3273 PF11677.8 OAP56563.1 - 2.1 7.6 7.2 2.5 7.4 1.4 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3273) FixP_N PF14715.6 OAP56563.1 - 9 6.1 5.7 2.3 8.0 0.1 2.5 2 0 0 2 2 2 0 N-terminal domain of cytochrome oxidase-cbb3, FixP ABC_tran PF00005.27 OAP56564.1 - 1.8e-46 158.0 0.1 3.7e-28 98.8 0.0 2.8 3 0 0 3 3 2 2 ABC transporter ABC_membrane PF00664.23 OAP56564.1 - 8.8e-37 127.2 38.4 5.4e-23 82.0 18.4 3.3 3 0 0 3 3 3 3 ABC transporter transmembrane region SMC_N PF02463.19 OAP56564.1 - 1.2e-14 54.3 2.0 6.1e-06 25.8 0.2 4.2 2 2 1 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 OAP56564.1 - 3.3e-09 37.6 0.7 0.0019 18.7 0.1 2.7 3 0 0 3 3 3 2 AAA domain AAA_21 PF13304.6 OAP56564.1 - 7.3e-08 32.6 0.7 0.04 13.7 0.0 4.4 3 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 OAP56564.1 - 4.1e-06 26.4 1.3 0.00074 19.2 0.3 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.6 OAP56564.1 - 5.1e-06 26.8 0.1 0.24 11.7 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 OAP56564.1 - 0.00014 22.3 4.0 0.43 10.9 0.4 3.7 3 1 0 3 3 3 2 AAA ATPase domain T2SSE PF00437.20 OAP56564.1 - 0.00018 20.7 3.4 0.032 13.3 0.2 2.7 3 0 0 3 3 3 2 Type II/IV secretion system protein cobW PF02492.19 OAP56564.1 - 0.0018 17.9 0.9 1 8.9 0.0 2.5 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.6 OAP56564.1 - 0.0022 17.6 0.2 0.037 13.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 OAP56564.1 - 0.0028 17.7 0.1 0.39 10.8 0.1 2.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OAP56564.1 - 0.016 15.2 0.3 2.8 7.8 0.0 2.9 3 0 0 3 3 2 0 RsgA GTPase Dynamin_N PF00350.23 OAP56564.1 - 0.019 15.0 0.3 1.7 8.6 0.0 3.1 3 0 0 3 3 3 0 Dynamin family DUF87 PF01935.17 OAP56564.1 - 0.02 15.0 0.4 0.02 15.0 0.4 1.8 2 0 0 2 2 2 0 Helicase HerA, central domain ATPase_2 PF01637.18 OAP56564.1 - 0.023 14.6 0.1 1.6 8.6 0.0 2.7 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_33 PF13671.6 OAP56564.1 - 0.063 13.4 0.9 8.6 6.5 0.2 2.7 2 1 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 OAP56564.1 - 0.092 12.1 1.0 0.74 9.1 0.2 2.6 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_18 PF13238.6 OAP56564.1 - 0.16 12.5 0.0 8 7.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 OAP56564.1 - 0.24 11.3 3.6 2.8 7.8 0.1 3.5 5 0 0 5 5 4 0 NACHT domain NTPase_1 PF03266.15 OAP56564.1 - 0.26 11.2 0.7 0.94 9.4 0.0 2.3 3 0 0 3 3 2 0 NTPase IstB_IS21 PF01695.17 OAP56564.1 - 1.1 9.0 4.0 4.1 7.1 0.0 3.3 5 0 0 5 5 4 0 IstB-like ATP binding protein Bac_luciferase PF00296.20 OAP56565.1 - 2e-58 198.3 0.3 2.8e-58 197.8 0.3 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase RP-C_C PF11800.8 OAP56567.1 - 0.49 10.4 2.9 0.34 11.0 1.6 1.4 2 0 0 2 2 2 0 Replication protein C C-terminal region FAD_binding_4 PF01565.23 OAP56568.1 - 2.3e-27 95.4 0.0 4.8e-27 94.4 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.19 OAP56568.1 - 2.9e-07 30.4 0.0 4.6e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain Sugar_tr PF00083.24 OAP56569.1 - 6.1e-106 355.0 24.0 6.9e-106 354.8 24.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP56569.1 - 9.4e-16 57.7 42.5 3.4e-15 55.8 36.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 OAP56569.1 - 0.00045 18.8 0.8 0.00076 18.0 0.8 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) p450 PF00067.22 OAP56570.1 - 2e-53 181.8 0.0 2.6e-53 181.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.18 OAP56571.1 - 3.8e-21 75.3 0.0 4.5e-21 75.1 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain NUDIX PF00293.28 OAP56571.1 - 0.077 13.0 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 NUDIX domain FMO-like PF00743.19 OAP56572.1 - 6.1e-24 84.3 0.0 3.2e-19 68.7 0.1 2.3 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OAP56572.1 - 1e-11 44.7 0.1 7.9e-09 35.2 0.3 3.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAP56572.1 - 7.9e-11 41.7 0.0 5.1e-09 35.8 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAP56572.1 - 2.5e-08 33.4 0.0 0.00028 20.1 0.0 3.2 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 OAP56572.1 - 2.2e-07 31.0 0.2 6.2e-07 29.5 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAP56572.1 - 2.7e-06 27.2 0.1 1.9e-05 24.4 0.1 2.2 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 OAP56572.1 - 0.00091 19.7 0.1 2.4 8.8 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAP56572.1 - 0.0023 18.0 0.0 0.049 13.6 0.0 3.0 3 0 0 3 3 3 1 FAD-NAD(P)-binding Shikimate_DH PF01488.20 OAP56572.1 - 0.0025 17.9 0.1 0.9 9.6 0.0 2.5 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.24 OAP56572.1 - 0.0077 15.4 0.3 0.012 14.7 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 OAP56572.1 - 0.053 12.8 0.1 0.11 11.8 0.1 1.4 1 0 0 1 1 1 0 Thi4 family 2-Hacid_dh_C PF02826.19 OAP56572.1 - 0.18 11.2 0.1 0.47 9.8 0.0 1.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HI0933_like PF03486.14 OAP56572.1 - 0.35 9.5 1.1 0.57 8.8 1.1 1.3 1 0 0 1 1 1 0 HI0933-like protein Fungal_trans_2 PF11951.8 OAP56573.1 - 6.9e-06 25.1 0.7 1.1e-05 24.5 0.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain AA_permease_2 PF13520.6 OAP56574.1 - 3.8e-48 164.4 50.6 4.7e-48 164.1 50.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAP56574.1 - 6e-14 51.5 33.4 9.4e-14 50.9 33.4 1.2 1 0 0 1 1 1 1 Amino acid permease Mg_trans_NIPA PF05653.14 OAP56575.1 - 9.6e-91 303.9 26.4 1.2e-90 303.6 26.4 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 OAP56575.1 - 0.00011 22.3 6.1 0.00011 22.3 6.1 3.2 3 0 0 3 3 3 1 EamA-like transporter family DUF805 PF05656.14 OAP56575.1 - 3.7 8.0 13.4 4.5 7.7 3.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF805) Synaptobrevin PF00957.21 OAP56576.1 - 0.025 14.4 0.8 0.054 13.3 0.8 1.5 1 0 0 1 1 1 0 Synaptobrevin DUF2024 PF09630.10 OAP56576.1 - 0.033 14.1 0.8 0.13 12.2 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF2024) Pcc1 PF09341.10 OAP56576.1 - 0.039 14.1 0.1 0.086 13.0 0.1 1.5 1 0 0 1 1 1 0 Transcription factor Pcc1 DUF3958 PF13125.6 OAP56576.1 - 0.11 12.7 7.6 0.2 11.9 5.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3958) DUF5595 PF18077.1 OAP56576.1 - 0.6 10.2 3.1 1.3 9.2 3.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5595) DivIC PF04977.15 OAP56576.1 - 1.5 8.6 6.5 3.1 7.6 6.5 1.4 1 0 0 1 1 1 0 Septum formation initiator bZIP_2 PF07716.15 OAP56576.1 - 1.6 8.8 9.0 4.6 7.4 9.0 1.8 1 0 0 1 1 1 0 Basic region leucine zipper zf-C2H2_4 PF13894.6 OAP56576.1 - 3 8.9 5.2 0.54 11.2 1.0 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger Paralemmin PF03285.15 OAP56576.1 - 8.4 5.9 9.0 0.22 11.0 0.4 2.3 2 0 0 2 2 2 0 Paralemmin Amidase PF01425.21 OAP56577.1 - 1.4e-105 353.9 0.0 1.7e-105 353.6 0.0 1.1 1 0 0 1 1 1 1 Amidase 2OG-FeII_Oxy_2 PF13532.6 OAP56578.1 - 5.9e-35 121.2 0.0 8.3e-34 117.5 0.0 2.0 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily FUSC_2 PF13515.6 OAP56579.1 - 1.9e-30 105.6 2.2 1.9e-30 105.6 2.2 2.8 2 1 0 2 2 2 1 Fusaric acid resistance protein-like ALMT PF11744.8 OAP56579.1 - 5.7e-07 28.7 17.2 0.0016 17.4 0.7 4.1 4 1 0 4 4 4 3 Aluminium activated malate transporter ArAE_2 PF10334.9 OAP56579.1 - 4.5e-05 23.4 0.4 0.00013 21.9 0.2 1.8 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 FUSC-like PF12805.7 OAP56579.1 - 0.0026 16.9 5.9 0.0078 15.3 0.2 3.1 3 1 0 3 3 3 1 FUSC-like inner membrane protein yccS FUSC PF04632.12 OAP56579.1 - 0.0072 14.9 18.1 0.29 9.6 0.1 3.5 2 1 0 2 2 2 2 Fusaric acid resistance protein family ArAE_2_N PF10337.9 OAP56579.1 - 0.016 14.3 7.7 0.054 12.5 0.2 2.8 2 1 1 3 3 3 0 Putative ER transporter, 6TM, N-terminal DUF572 PF04502.13 OAP56580.1 - 0.014 15.1 3.7 0.021 14.5 3.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF2076 PF09849.9 OAP56580.1 - 0.34 10.9 6.1 0.75 9.8 6.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Epimerase PF01370.21 OAP56581.1 - 2.3e-23 82.9 0.0 1.7e-22 80.1 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAP56581.1 - 6.1e-15 55.4 0.0 2.1e-14 53.7 0.0 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 OAP56581.1 - 9.9e-08 31.3 0.0 8.2e-07 28.3 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 OAP56581.1 - 2.9e-07 29.9 0.0 6.8e-07 28.7 0.0 1.5 2 0 0 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.6 OAP56581.1 - 3.6e-05 23.7 0.0 7e-05 22.8 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 OAP56581.1 - 4.1e-05 22.8 0.0 6.2e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 OAP56581.1 - 7.4e-05 22.0 0.0 0.00015 21.0 0.0 1.6 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Mod_r PF07200.13 OAP56582.1 - 0.22 11.6 22.9 0.43 10.7 12.1 3.3 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF5082 PF16888.5 OAP56582.1 - 0.64 10.3 16.3 1 9.7 13.8 2.8 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) Tup_N PF08581.10 OAP56582.1 - 0.67 10.3 11.9 0.43 10.9 5.9 3.1 1 1 0 2 2 2 0 Tup N-terminal CorA PF01544.18 OAP56583.1 - 4e-40 137.9 0.3 1.6e-38 132.7 0.3 2.3 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein XhlA PF10779.9 OAP56583.1 - 0.15 12.3 2.4 0.37 11.0 2.4 1.7 1 0 0 1 1 1 0 Haemolysin XhlA Sugar_tr PF00083.24 OAP56584.1 - 9.8e-63 212.6 16.2 1.1e-62 212.4 16.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP56584.1 - 8.1e-12 44.7 17.3 8.1e-12 44.7 17.3 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF3493 PF11998.8 OAP56584.1 - 1.4 9.2 6.7 11 6.2 0.3 3.5 3 0 0 3 3 3 0 Low psii accumulation1 / Rep27 Fe-ADH PF00465.19 OAP56586.1 - 4.1e-70 236.4 0.4 4.8e-70 236.2 0.4 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 OAP56586.1 - 1.6e-14 54.3 0.2 2e-14 53.9 0.2 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase COesterase PF00135.28 OAP56587.1 - 7.3e-58 196.7 0.0 1.5e-49 169.2 0.0 2.0 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 OAP56587.1 - 2.7e-08 33.9 0.0 4.3e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold CMD PF02627.20 OAP56588.1 - 7e-08 32.4 0.0 1.4e-05 25.0 0.0 2.6 2 1 1 3 3 3 2 Carboxymuconolactone decarboxylase family PRMT5_C PF17286.2 OAP56588.1 - 0.16 11.8 0.0 0.16 11.8 0.0 1.1 1 0 0 1 1 1 0 PRMT5 oligomerisation domain HgmA PF04209.13 OAP56589.1 - 4.8e-154 513.1 0.0 5.5e-154 512.9 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase DUF3500 PF12006.8 OAP56590.1 - 6e-54 183.5 0.0 2.1e-53 181.8 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3500) But2 PF09792.9 OAP56591.1 - 1.4e-07 32.0 0.4 4.3e-07 30.4 0.0 1.9 2 1 0 2 2 2 1 Ubiquitin 3 binding protein But2 C-terminal domain fn3_2 PF16893.5 OAP56592.1 - 8.8e-37 125.1 0.3 1.5e-36 124.4 0.3 1.4 1 0 0 1 1 1 1 Fibronectin type III domain CHS5_N PF16892.5 OAP56592.1 - 3.3e-23 81.4 0.4 5.5e-23 80.7 0.4 1.4 1 0 0 1 1 1 1 Chitin biosynthesis protein CHS5 N-terminus PTCB-BRCT PF12738.7 OAP56592.1 - 1.1e-14 54.1 0.0 2.6e-14 52.9 0.0 1.6 2 0 0 2 2 2 1 twin BRCT domain BRCT PF00533.26 OAP56592.1 - 1.2e-09 38.4 0.0 2.2e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DUF3006 PF11213.8 OAP56592.1 - 0.00016 21.9 1.6 0.00025 21.2 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3006) BRCT_2 PF16589.5 OAP56592.1 - 0.00028 21.2 0.0 0.00064 20.1 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain fn3 PF00041.21 OAP56592.1 - 0.028 14.8 0.1 0.13 12.6 0.1 2.1 1 1 0 1 1 1 0 Fibronectin type III domain Ribonuclease_P PF00825.18 OAP56593.1 - 0.036 14.2 0.7 0.059 13.4 0.7 1.3 1 0 0 1 1 1 0 Ribonuclease P eIF-1a PF01176.19 OAP56594.1 - 8.1e-22 76.8 0.0 1.1e-21 76.3 0.0 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 ERCC4 PF02732.15 OAP56595.1 - 6.9e-18 65.3 0.0 1.4e-17 64.3 0.0 1.6 1 0 0 1 1 1 1 ERCC4 domain HHH_5 PF14520.6 OAP56595.1 - 0.069 13.8 0.0 0.24 12.1 0.0 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix domain Patatin PF01734.22 OAP56596.1 - 1.1e-17 65.0 0.0 1.8e-17 64.2 0.0 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase Zn_clus PF00172.18 OAP56597.1 - 2.6e-10 40.2 12.9 4.1e-10 39.6 12.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FlxA PF14282.6 OAP56597.1 - 0.27 11.2 4.4 0.65 10.0 4.4 1.5 1 0 0 1 1 1 0 FlxA-like protein CinA PF02464.17 OAP56599.1 - 6.3e-27 94.0 0.4 2.3e-19 69.5 0.1 2.0 2 0 0 2 2 2 2 Competence-damaged protein Sugar_tr PF00083.24 OAP56600.1 - 1.2e-75 255.1 21.2 1.4e-75 254.9 21.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP56600.1 - 8.7e-19 67.6 21.6 8.7e-19 67.6 21.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily 5-FTHF_cyc-lig PF01812.20 OAP56601.1 - 7.1e-15 55.3 0.0 9.2e-15 55.0 0.0 1.2 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family ADH_N PF08240.12 OAP56602.1 - 9.8e-18 64.0 2.4 2e-17 63.1 2.4 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAP56602.1 - 2.4e-09 37.2 0.0 4.5e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 OAP56602.1 - 0.00037 19.9 0.1 0.0006 19.2 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.6 OAP56602.1 - 0.0076 17.3 0.0 0.011 16.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 OAP56602.1 - 0.13 11.6 0.0 0.25 10.6 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Baculo_E25 PF05274.11 OAP56602.1 - 0.24 11.2 0.0 1.1 9.1 0.0 1.9 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein E25 Ydc2-catalyt PF09159.10 OAP56603.1 - 8.9e-68 229.0 0.0 1.2e-67 228.6 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 Pox_A22 PF04848.13 OAP56603.1 - 0.0012 19.0 0.0 0.14 12.3 0.0 2.7 3 0 0 3 3 3 2 Poxvirus A22 protein Malate_synthase PF01274.22 OAP56604.1 - 8.6e-226 750.2 0.0 9.8e-226 750.1 0.0 1.0 1 0 0 1 1 1 1 Malate synthase Epimerase PF01370.21 OAP56605.1 - 2.5e-17 63.2 0.0 3.4e-17 62.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAP56605.1 - 2.7e-10 40.2 0.0 2.8e-09 36.8 0.0 2.1 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 OAP56605.1 - 8e-10 38.3 0.0 0.00022 20.5 0.0 2.6 2 1 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.19 OAP56605.1 - 3e-09 36.3 0.0 3.9e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 OAP56605.1 - 1.6e-06 27.4 0.0 5.1e-06 25.8 0.0 1.8 1 1 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 OAP56605.1 - 0.04 13.1 0.0 0.24 10.5 0.0 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Ldh_1_N PF00056.23 OAP56605.1 - 0.072 13.2 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain adh_short PF00106.25 OAP56605.1 - 0.076 12.5 0.0 0.25 10.8 0.0 1.9 2 0 0 2 2 2 0 short chain dehydrogenase KR PF08659.10 OAP56605.1 - 0.13 12.2 0.0 1 9.3 0.0 2.2 2 0 0 2 2 2 0 KR domain F_bP_aldolase PF01116.20 OAP56606.1 - 5.7e-75 252.4 0.0 7e-75 252.1 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Methyltransf_24 PF13578.6 OAP56606.1 - 0.045 14.8 0.0 0.092 13.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain CUE PF02845.16 OAP56607.1 - 1.9e-10 40.2 0.0 4.8e-10 38.9 0.0 1.7 2 0 0 2 2 2 1 CUE domain Helicase_C PF00271.31 OAP56608.1 - 5.3e-13 49.3 0.0 1.4e-12 48.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 OAP56608.1 - 6.7e-13 48.8 0.0 1.9e-12 47.3 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 OAP56608.1 - 2.1e-12 47.3 0.0 5.2e-12 46.0 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) AAA_22 PF13401.6 OAP56608.1 - 2.4e-06 27.9 0.2 7.5e-06 26.3 0.1 1.9 2 0 0 2 2 1 1 AAA domain DEAD PF00270.29 OAP56608.1 - 3.8e-06 26.8 0.3 9.4e-06 25.5 0.1 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_30 PF13604.6 OAP56608.1 - 7.6e-06 25.8 0.0 1.7e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OAP56608.1 - 0.00013 22.3 0.2 0.00053 20.3 0.1 2.0 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 OAP56608.1 - 0.0032 18.0 0.1 0.1 13.1 0.1 2.7 1 1 0 1 1 1 1 ABC transporter AAA_14 PF13173.6 OAP56608.1 - 0.005 16.9 0.2 0.65 10.0 0.0 2.6 1 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OAP56608.1 - 0.0087 16.5 0.6 0.03 14.7 0.1 2.1 2 1 0 2 2 1 1 AAA ATPase domain cobW PF02492.19 OAP56608.1 - 0.014 15.0 0.1 0.18 11.4 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Flavi_DEAD PF07652.14 OAP56608.1 - 0.029 14.4 0.0 0.053 13.5 0.0 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain DUF2075 PF09848.9 OAP56608.1 - 0.036 13.3 0.0 0.074 12.3 0.0 1.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_33 PF13671.6 OAP56608.1 - 0.042 14.0 0.2 0.11 12.6 0.2 1.9 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.6 OAP56608.1 - 0.044 13.6 0.0 0.43 10.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 OAP56608.1 - 0.054 13.2 0.3 7.1 6.3 0.0 2.3 1 1 1 2 2 2 0 IstB-like ATP binding protein T2SSE PF00437.20 OAP56608.1 - 0.06 12.4 0.0 0.12 11.4 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.6 OAP56608.1 - 0.084 12.6 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain SRP54 PF00448.22 OAP56608.1 - 0.11 12.2 0.6 1.3 8.6 0.0 2.8 4 0 0 4 4 4 0 SRP54-type protein, GTPase domain Zeta_toxin PF06414.12 OAP56608.1 - 0.16 11.3 0.4 0.49 9.6 0.1 1.9 1 1 1 2 2 2 0 Zeta toxin AAA_23 PF13476.6 OAP56608.1 - 0.21 12.0 1.9 0.28 11.6 0.1 2.0 3 0 0 3 3 2 0 AAA domain DEAD PF00270.29 OAP56609.1 - 8.7e-16 58.2 0.0 1.4e-15 57.5 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAP56609.1 - 1e-13 51.6 0.0 7.4e-13 48.8 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 OAP56609.1 - 1.1e-08 35.7 11.0 5.1e-08 33.5 11.1 2.2 1 1 1 2 2 2 1 RecQ zinc-binding MmgE_PrpD PF03972.14 OAP56609.1 - 0.018 13.6 0.1 0.035 12.7 0.1 1.4 1 0 0 1 1 1 0 MmgE/PrpD family CLCA PF08434.11 OAP56609.1 - 0.11 11.8 1.2 0.19 11.0 1.2 1.3 1 0 0 1 1 1 0 Calcium-activated chloride channel N terminal BDV_P40 PF06407.11 OAP56609.1 - 0.16 11.1 0.0 0.29 10.2 0.0 1.4 1 0 0 1 1 1 0 Borna disease virus P40 protein Fungal_trans_2 PF11951.8 OAP56610.1 - 0.0007 18.5 0.3 0.0011 17.9 0.1 1.4 2 0 0 2 2 2 1 Fungal specific transcription factor domain Peptidase_A22B PF04258.13 OAP56611.1 - 2.6e-60 204.3 4.0 1.1e-59 202.3 4.0 2.1 1 1 0 1 1 1 1 Signal peptide peptidase SPP PF06550.11 OAP56611.1 - 5.5e-07 29.4 3.4 5.5e-07 29.4 3.4 2.0 2 0 0 2 2 2 1 Signal-peptide peptidase, presenilin aspartyl protease Luciferase_cat PF10285.9 OAP56611.1 - 0.11 11.8 0.1 0.2 11.0 0.1 1.3 1 0 0 1 1 1 0 Luciferase catalytic domain WH1 PF00568.23 OAP56613.1 - 2.2e-28 98.4 0.1 3.1e-28 97.9 0.1 1.2 1 0 0 1 1 1 1 WH1 domain WH2 PF02205.20 OAP56613.1 - 0.084 12.7 5.8 0.47 10.4 5.8 2.3 1 1 0 1 1 1 0 WH2 motif DCP1 PF06058.13 OAP56613.1 - 0.24 11.3 0.0 0.37 10.7 0.0 1.3 1 0 0 1 1 1 0 Dcp1-like decapping family CorA PF01544.18 OAP56614.1 - 4.2e-09 36.2 0.2 9e-09 35.1 0.2 1.5 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein ApoL PF05461.11 OAP56614.1 - 0.046 13.0 1.1 0.11 11.8 0.8 1.7 1 1 0 1 1 1 0 Apolipoprotein L AA_permease_2 PF13520.6 OAP56614.1 - 0.11 11.3 0.1 0.17 10.7 0.1 1.1 1 0 0 1 1 1 0 Amino acid permease DUF2371 PF10177.9 OAP56615.1 - 0.24 11.5 0.0 0.45 10.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) Asp PF00026.23 OAP56616.1 - 0.0027 17.2 0.0 0.0035 16.8 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Insulin_TMD PF17870.1 OAP56616.1 - 2.4 8.3 3.8 1.3 9.1 0.8 2.0 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment MFS_1 PF07690.16 OAP56617.1 - 5.4e-33 114.4 24.0 8e-33 113.8 24.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAP56617.1 - 1.7e-11 43.7 7.1 3e-11 42.8 7.1 1.4 1 0 0 1 1 1 1 Sugar (and other) transporter PTR2 PF00854.21 OAP56617.1 - 0.028 13.3 2.0 0.049 12.5 2.0 1.4 1 0 0 1 1 1 0 POT family TRI12 PF06609.13 OAP56617.1 - 0.052 12.0 5.3 0.08 11.3 5.3 1.2 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) MOSC PF03473.17 OAP56618.1 - 3.2e-31 108.1 0.0 5e-31 107.4 0.0 1.3 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 OAP56618.1 - 1.4e-05 25.0 0.0 2.9e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain BRCT_2 PF16589.5 OAP56619.1 - 3.8e-10 40.1 0.0 6.4e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 OAP56619.1 - 0.0033 17.7 0.0 0.0064 16.8 0.0 1.4 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain BRCT PF00533.26 OAP56619.1 - 0.029 14.8 0.0 0.052 13.9 0.0 1.5 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 OAP56619.1 - 0.043 13.8 1.0 0.18 11.7 1.0 2.1 1 1 0 1 1 1 0 twin BRCT domain Reprolysin_4 PF13583.6 OAP56619.1 - 0.079 12.6 0.1 0.12 12.0 0.1 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Meth_synt_2 PF01717.18 OAP56620.1 - 2.6e-150 500.2 0.0 4.4e-146 486.3 0.0 2.3 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 OAP56620.1 - 8.4e-119 396.7 0.0 2.8e-112 375.3 0.0 3.0 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain VbhA PF18495.1 OAP56620.1 - 0.0014 18.4 0.8 0.41 10.5 0.0 3.1 4 0 0 4 4 4 2 Antitoxin VbhA URO-D PF01208.17 OAP56620.1 - 0.024 13.8 0.0 0.21 10.7 0.0 2.3 2 0 0 2 2 2 0 Uroporphyrinogen decarboxylase (URO-D) SHOCT PF09851.9 OAP56620.1 - 0.33 10.8 3.9 0.49 10.2 0.2 2.9 3 0 0 3 3 3 0 Short C-terminal domain Steroid_dh PF02544.16 OAP56621.1 - 2.5e-09 37.3 2.3 1.8e-08 34.5 2.3 2.0 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 OAP56621.1 - 0.0017 17.9 3.0 0.0033 17.0 3.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) DUF3169 PF11368.8 OAP56621.1 - 0.053 13.0 0.0 0.083 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) CBFB_NFYA PF02045.15 OAP56622.1 - 1.6e-08 35.0 0.2 3.8e-08 33.8 0.2 1.6 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B CorA PF01544.18 OAP56622.1 - 2.8e-06 26.9 1.1 5.8e-06 25.8 1.1 1.5 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein ALS_ss_C PF10369.9 OAP56623.1 - 8e-15 54.8 0.0 7.5e-14 51.7 0.0 2.2 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.25 OAP56623.1 - 1.8e-14 53.2 0.1 9.1e-14 50.9 0.1 2.2 2 0 0 2 2 2 1 ACT domain ACT_5 PF13710.6 OAP56623.1 - 3.3e-08 33.2 0.0 6.7e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.6 OAP56623.1 - 0.07 13.1 0.0 13 5.9 0.0 2.6 2 0 0 2 2 2 0 ACT domain Glyco_hydro_28 PF00295.17 OAP56624.1 - 9.9e-32 110.3 7.3 1.3e-18 67.1 1.1 2.0 2 0 0 2 2 2 2 Glycosyl hydrolases family 28 Beta_helix PF13229.6 OAP56624.1 - 2.4 8.0 14.5 0.7 9.7 5.8 2.5 2 0 0 2 2 2 0 Right handed beta helix region Carb_anhydrase PF00194.21 OAP56625.1 - 1.1e-25 90.7 0.2 1.9e-25 89.9 0.2 1.4 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase DUF924 PF06041.11 OAP56626.1 - 3.9e-54 183.5 0.0 5e-54 183.2 0.0 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF924) Aa_trans PF01490.18 OAP56627.1 - 6.2e-63 212.9 15.6 7.2e-63 212.7 15.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DotU PF09850.9 OAP56627.1 - 0.089 12.5 0.0 0.27 10.9 0.0 1.8 1 0 0 1 1 1 0 Type VI secretion system protein DotU MCR PF18509.1 OAP56627.1 - 0.15 11.7 1.7 0.23 11.1 0.6 1.9 2 0 0 2 2 2 0 Magnetochrome domain eRF1_2 PF03464.15 OAP56628.1 - 4e-48 163.1 0.1 7.6e-48 162.2 0.1 1.5 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 OAP56628.1 - 6.3e-39 133.0 0.6 1.4e-38 131.9 0.6 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 OAP56628.1 - 3.4e-21 75.6 0.0 5.6e-21 74.9 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 baeRF_family10 PF18854.1 OAP56628.1 - 3.2e-10 40.4 0.0 6.6e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 acVLRF1 PF18859.1 OAP56628.1 - 4.8e-10 39.8 0.1 9.9e-10 38.8 0.1 1.5 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor PDT PF00800.18 OAP56629.1 - 2e-47 161.4 0.0 3.4e-47 160.6 0.0 1.4 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.25 OAP56629.1 - 1.8e-05 24.4 0.0 4e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 ACT domain Creatinase_N_2 PF16189.5 OAP56630.1 - 2.7e-54 183.6 0.1 2.6e-53 180.4 0.0 2.3 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 OAP56630.1 - 2.2e-41 141.9 0.1 4e-41 141.0 0.1 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M24_C PF16188.5 OAP56630.1 - 5.6e-26 90.4 0.3 1.5e-25 89.0 0.3 1.8 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 OAP56630.1 - 1.5e-23 83.9 0.0 4.4e-21 75.9 0.0 2.4 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain Importin_rep_3 PF18806.1 OAP56631.1 - 0.00033 20.6 0.0 0.0025 17.8 0.0 2.6 2 0 0 2 2 2 1 Importin 13 repeat IBN_N PF03810.19 OAP56631.1 - 0.0023 17.8 0.0 0.011 15.7 0.0 2.3 1 0 0 1 1 1 1 Importin-beta N-terminal domain EF-hand_2 PF09068.11 OAP56631.1 - 0.11 12.6 1.5 0.4 10.8 0.6 2.4 2 0 0 2 2 2 0 EF hand CamS PF07537.11 OAP56631.1 - 0.17 11.0 0.0 0.31 10.2 0.0 1.3 1 0 0 1 1 1 0 CamS sex pheromone cAM373 precursor Importin_rep PF18773.1 OAP56631.1 - 0.19 11.5 1.2 0.32 10.7 0.2 1.9 2 0 0 2 2 2 0 Importin 13 repeat Sec8_exocyst PF04048.14 OAP56632.1 - 6.5e-38 129.8 0.0 1.8e-37 128.4 0.0 1.8 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain Vps54_N PF10475.9 OAP56632.1 - 6e-09 35.6 0.1 1.2e-08 34.6 0.1 1.4 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex AAA_12 PF13087.6 OAP56632.1 - 0.016 14.9 0.0 0.029 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Vps51 PF08700.11 OAP56632.1 - 0.022 14.8 0.6 2 8.6 0.0 3.2 3 0 0 3 3 3 0 Vps51/Vps67 Zw10 PF06248.13 OAP56632.1 - 0.071 11.7 0.2 0.6 8.6 0.1 2.3 3 0 0 3 3 3 0 Centromere/kinetochore Zw10 COG2 PF06148.11 OAP56632.1 - 0.33 11.0 2.2 0.36 10.9 0.1 2.1 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Zn_clus PF00172.18 OAP56633.1 - 1.4e-08 34.7 14.2 2.2e-08 34.0 14.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain cwf21 PF08312.12 OAP56634.1 - 1.2e-15 57.4 15.0 3.2e-15 56.0 15.0 1.8 1 0 0 1 1 1 1 cwf21 domain YjbH PF06082.11 OAP56634.1 - 0.027 13.3 0.5 0.03 13.2 0.5 1.0 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH Hus1 PF04005.12 OAP56636.1 - 9.9e-91 303.9 0.0 1.1e-90 303.7 0.0 1.0 1 0 0 1 1 1 1 Hus1-like protein GAS2 PF02187.17 OAP56637.1 - 3.9e-06 26.9 0.2 8.1e-06 25.8 0.2 1.4 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain Glyco_transf_25 PF01755.17 OAP56638.1 - 0.015 15.1 0.0 0.75 9.6 0.0 2.2 2 0 0 2 2 2 0 Glycosyltransferase family 25 (LPS biosynthesis protein) Oxidored_FMN PF00724.20 OAP56639.1 - 1.6e-42 146.0 0.0 2e-42 145.7 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Na_H_Exchanger PF00999.21 OAP56640.1 - 4.2e-71 239.8 40.3 5.1e-71 239.5 40.3 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family NiFe_hyd_3_EhaA PF17367.2 OAP56640.1 - 2.8 8.1 14.7 0.84 9.8 1.4 3.8 2 1 1 3 3 3 0 NiFe-hydrogenase-type-3 Eha complex subunit A SNF2_N PF00176.23 OAP56641.1 - 6.7e-73 245.4 1.0 6.7e-73 245.4 1.0 2.0 2 0 0 2 2 2 1 SNF2 family N-terminal domain Bromodomain PF00439.25 OAP56641.1 - 2.9e-21 75.3 0.2 8e-21 73.9 0.2 1.7 1 0 0 1 1 1 1 Bromodomain Helicase_C PF00271.31 OAP56641.1 - 6.9e-21 74.7 1.6 1e-18 67.7 0.0 3.7 3 1 1 4 4 4 1 Helicase conserved C-terminal domain HSA PF07529.13 OAP56641.1 - 7e-20 71.1 12.6 7e-20 71.1 12.6 5.0 4 1 1 5 5 5 1 HSA SnAC PF14619.6 OAP56641.1 - 7.1e-13 49.0 3.0 7.1e-13 49.0 3.0 4.2 4 1 1 5 5 5 1 Snf2-ATP coupling, chromatin remodelling complex ResIII PF04851.15 OAP56641.1 - 1.6e-11 44.5 0.0 1.6e-11 44.5 0.0 3.5 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit QLQ PF08880.11 OAP56641.1 - 7e-10 38.5 4.0 7e-10 38.5 4.0 2.7 2 0 0 2 2 2 1 QLQ BAR PF03114.18 OAP56642.1 - 6.6e-48 163.4 8.7 8.3e-48 163.1 8.7 1.1 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.9 OAP56642.1 - 2.2e-05 23.8 3.8 3.1e-05 23.3 3.8 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR_3 PF16746.5 OAP56642.1 - 5.6e-05 23.0 5.9 0.00011 22.1 5.9 1.4 1 1 0 1 1 1 1 BAR domain of APPL family PMEI PF04043.15 OAP56642.1 - 0.0045 17.3 4.1 0.034 14.5 2.3 2.2 1 1 1 2 2 2 1 Plant invertase/pectin methylesterase inhibitor DUF2018 PF09442.10 OAP56642.1 - 0.19 12.7 3.2 0.25 12.3 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF2018) APG6_N PF17675.1 OAP56642.1 - 0.27 11.8 12.8 0.61 10.6 12.6 1.7 1 1 0 1 1 1 0 Apg6 coiled-coil region GBP_C PF02841.14 OAP56642.1 - 0.27 10.6 11.4 0.018 14.5 6.6 1.4 2 0 0 2 2 2 0 Guanylate-binding protein, C-terminal domain ZapA PF05164.13 OAP56642.1 - 0.27 11.7 7.0 0.39 11.2 1.5 3.0 2 1 1 3 3 3 0 Cell division protein ZapA OmpH PF03938.14 OAP56642.1 - 1.5 9.2 12.6 2.5 8.4 8.6 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Strep_SA_rep PF06696.11 OAP56642.1 - 4 7.5 7.5 5.4 7.1 0.0 3.3 3 0 0 3 3 3 0 Streptococcal surface antigen repeat Ribosomal_L2_C PF03947.18 OAP56643.1 - 1.5e-41 141.5 5.2 2.9e-41 140.6 5.2 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 OAP56643.1 - 1.5e-16 60.1 0.1 4.3e-16 58.6 0.1 1.8 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain WHIM1 PF15612.6 OAP56644.1 - 5.3e-05 22.6 0.0 0.00012 21.5 0.0 1.6 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 Nop14 PF04147.12 OAP56644.1 - 0.049 11.9 8.1 0.077 11.2 8.1 1.3 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.12 OAP56644.1 - 1.2 8.4 12.1 2.2 7.5 12.1 1.3 1 0 0 1 1 1 0 NOA36 protein Pkinase PF00069.25 OAP56645.1 - 7.7e-68 228.7 0.0 1.6e-67 227.6 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP56645.1 - 6.7e-50 169.8 0.0 1.8e-49 168.4 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Ras_bdg_2 PF14847.6 OAP56645.1 - 4.8e-29 100.6 0.1 9.7e-29 99.7 0.1 1.5 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_1 PF00536.30 OAP56645.1 - 5.7e-16 58.7 0.0 1.3e-15 57.6 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 OAP56645.1 - 2.6e-13 49.9 0.0 5.4e-13 48.9 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.23 OAP56645.1 - 1.7e-06 28.5 0.0 3.6e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Kinase-like PF14531.6 OAP56645.1 - 1.8e-05 24.2 0.0 0.014 14.7 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 OAP56645.1 - 0.0028 16.5 0.9 0.017 13.9 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 OAP56645.1 - 0.17 11.2 0.0 0.31 10.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MSA-2c PF12238.8 OAP56645.1 - 0.25 11.3 2.8 0.47 10.4 0.0 2.4 2 0 0 2 2 2 0 Merozoite surface antigen 2c zf-C2H2 PF00096.26 OAP56646.1 - 0.012 16.0 9.2 0.19 12.2 0.7 3.3 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAP56646.1 - 1.3 10.0 8.2 1.5 9.9 0.4 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger Lactamase_B PF00753.27 OAP56647.1 - 1.4e-06 28.5 3.0 1.7e-05 24.9 3.0 2.3 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OAP56647.1 - 0.00015 21.3 0.1 0.00026 20.6 0.1 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain FH2 PF02181.23 OAP56648.1 - 1.6e-84 284.2 6.2 2e-84 283.8 6.2 1.1 1 0 0 1 1 1 1 Formin Homology 2 Domain T3SSipB PF16535.5 OAP56648.1 - 0.19 12.2 7.5 0.062 13.8 1.1 3.1 3 1 0 3 3 3 0 Type III cell invasion protein SipB DUF5302 PF17227.2 OAP56648.1 - 0.23 12.5 0.1 0.23 12.5 0.1 3.6 3 0 0 3 3 3 0 Family of unknown function (DUF5302) HEPN_RiboL-PSP PF18735.1 OAP56648.1 - 4.4 7.2 8.0 0.3 11.0 0.1 2.7 3 1 0 3 3 3 0 RiboL-PSP-HEPN Drf_GBD PF06371.13 OAP56649.1 - 5.2e-65 218.5 0.0 5.2e-65 218.5 0.0 1.7 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 OAP56649.1 - 1.7e-51 174.7 1.0 1.7e-51 174.7 1.0 2.6 2 1 1 3 3 3 1 Diaphanous FH3 Domain FixQ PF05545.11 OAP56650.1 - 0.27 11.2 1.7 0.54 10.3 1.7 1.5 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ STE PF02200.16 OAP56651.1 - 6.8e-56 187.4 0.0 1.2e-55 186.6 0.0 1.4 1 0 0 1 1 1 1 STE like transcription factor zf-C2H2 PF00096.26 OAP56651.1 - 1.4e-11 44.2 10.8 3.5e-07 30.3 0.9 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OAP56651.1 - 4.9e-09 36.2 3.5 4.9e-09 36.2 3.5 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 OAP56651.1 - 4.2e-08 33.4 8.7 0.00029 21.4 0.5 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 OAP56651.1 - 3.3e-05 23.8 0.4 3.3e-05 23.8 0.4 2.4 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OAP56651.1 - 0.0026 18.0 0.4 0.032 14.5 0.1 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding FYDLN_acid PF09538.10 OAP56651.1 - 0.0086 16.7 1.3 0.022 15.5 1.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (FYDLN_acid) zf-Di19 PF05605.12 OAP56651.1 - 0.026 14.8 2.0 0.059 13.7 2.0 1.6 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zinc_ribbon_9 PF14369.6 OAP56651.1 - 0.054 13.8 0.1 0.12 12.6 0.1 1.6 1 0 0 1 1 1 0 zinc-ribbon zf-BED PF02892.15 OAP56651.1 - 0.12 12.4 1.5 0.55 10.3 0.8 2.3 2 0 0 2 2 2 0 BED zinc finger DUF4602 PF15375.6 OAP56652.1 - 2e-13 50.8 10.7 4.1e-13 49.8 10.7 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4602) DUF4702 PF15774.5 OAP56652.1 - 0.00016 20.8 0.3 0.00027 20.0 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4702) His_biosynth PF00977.21 OAP56653.1 - 6e-35 120.8 0.0 7.4e-35 120.5 0.0 1.1 1 0 0 1 1 1 1 Histidine biosynthesis protein Ribul_P_3_epim PF00834.19 OAP56653.1 - 0.15 11.4 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family Grg1 PF11034.8 OAP56655.1 - 3.1e-33 113.8 13.5 3.5e-33 113.6 13.5 1.0 1 0 0 1 1 1 1 Glucose-repressible protein Grg1 Glyoxalase PF00903.25 OAP56656.1 - 5.5e-06 26.6 0.0 1.3e-05 25.4 0.0 1.6 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 OAP56656.1 - 0.041 13.8 0.1 0.051 13.5 0.1 1.1 1 0 0 1 1 1 0 Glyoxalase-like domain AMPK1_CBM PF16561.5 OAP56656.1 - 0.12 12.6 0.0 0.21 11.9 0.0 1.3 1 0 0 1 1 1 0 Glycogen recognition site of AMP-activated protein kinase Abhydrolase_1 PF00561.20 OAP56657.1 - 3.4e-23 82.6 0.0 7.7e-22 78.2 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAP56657.1 - 5.7e-13 50.0 0.0 7.3e-13 49.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAP56657.1 - 1.5e-08 34.2 0.0 9.5e-05 21.8 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 FSH1 PF03959.13 OAP56657.1 - 0.004 16.8 0.0 0.32 10.6 0.0 2.3 2 1 0 2 2 2 1 Serine hydrolase (FSH1) Chlorophyllase2 PF12740.7 OAP56657.1 - 0.23 10.4 0.0 0.36 9.7 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme ECH_1 PF00378.20 OAP56658.1 - 1e-25 90.5 0.0 1.6e-25 89.9 0.0 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAP56658.1 - 1.4e-15 57.6 0.0 1.7e-15 57.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase UCH PF00443.29 OAP56658.1 - 0.054 13.0 0.0 0.078 12.5 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Abhydrolase_1 PF00561.20 OAP56659.1 - 4.7e-46 157.5 0.0 1.2e-45 156.2 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 OAP56659.1 - 0.00012 21.8 0.0 0.00024 20.9 0.0 1.4 1 0 0 1 1 1 1 Putative esterase ATP-synt_C PF00137.21 OAP56660.1 - 1.2e-27 96.0 37.1 7.1e-16 58.3 14.3 2.1 2 0 0 2 2 2 2 ATP synthase subunit C CNH PF00780.22 OAP56661.1 - 5.4e-77 259.1 0.0 3.1e-76 256.6 0.0 2.0 2 0 0 2 2 2 1 CNH domain PH_5 PF15405.6 OAP56661.1 - 1.1e-41 142.1 0.1 2.3e-41 141.1 0.1 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.20 OAP56661.1 - 2.6e-38 132.1 0.0 4.4e-38 131.3 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.21 OAP56661.1 - 5.5e-15 55.2 0.0 7.7e-14 51.5 0.0 2.3 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Brix PF04427.18 OAP56662.1 - 1.8e-24 86.9 0.0 3e-24 86.2 0.0 1.3 1 0 0 1 1 1 1 Brix domain PRIMA1 PF16101.5 OAP56662.1 - 0.44 10.6 3.3 0.8 9.8 3.3 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 BUD22 PF09073.10 OAP56662.1 - 0.53 9.6 17.4 0.81 9.0 17.4 1.2 1 0 0 1 1 1 0 BUD22 TFIIA PF03153.13 OAP56662.1 - 8 6.3 14.6 14 5.5 14.6 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit HGTP_anticodon PF03129.20 OAP56663.1 - 7.6e-22 77.3 0.0 7.6e-22 77.3 0.0 3.2 3 1 0 3 3 3 1 Anticodon binding domain tRNA-synt_2b PF00587.25 OAP56663.1 - 6.6e-08 32.7 0.0 2e-07 31.1 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) FAD_binding_3 PF01494.19 OAP56664.1 - 4e-53 180.9 0.0 5.2e-53 180.5 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAP56664.1 - 3.2e-08 33.5 1.2 0.00093 18.9 0.5 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OAP56664.1 - 3.1e-07 29.8 0.3 0.015 14.4 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 OAP56664.1 - 1.2e-05 24.7 0.0 0.00061 19.1 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAP56664.1 - 2.9e-05 24.5 0.1 0.028 15.0 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAP56664.1 - 0.00018 20.4 0.0 0.011 14.4 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein ApbA PF02558.16 OAP56664.1 - 0.0003 20.5 0.1 0.00065 19.4 0.1 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_8 PF13450.6 OAP56664.1 - 0.0005 20.2 0.1 0.0014 18.8 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 OAP56664.1 - 0.0064 15.8 0.0 1.3 8.2 0.0 2.4 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase NAD_binding_7 PF13241.6 OAP56664.1 - 0.014 15.8 0.0 0.034 14.6 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox_3 PF13738.6 OAP56664.1 - 0.02 14.2 0.1 1.4 8.1 0.0 2.4 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Glu_dehyd_C PF16912.5 OAP56664.1 - 0.056 12.9 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus FAD_oxidored PF12831.7 OAP56664.1 - 0.14 11.5 0.4 3.6 6.8 0.6 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 OAP56664.1 - 0.19 10.7 0.2 8 5.4 0.1 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein Trp_halogenase PF04820.14 OAP56664.1 - 0.2 10.5 0.1 0.56 9.0 0.2 1.6 2 0 0 2 2 2 0 Tryptophan halogenase GIDA PF01134.22 OAP56664.1 - 0.21 10.7 0.2 0.29 10.2 0.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD-oxidase_C PF02913.19 OAP56665.1 - 2.4e-50 171.5 2.0 3.6e-50 170.9 2.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 OAP56665.1 - 4.7e-38 130.1 0.4 1.7e-37 128.2 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain Dehydrin PF00257.19 OAP56665.1 - 2.2 8.8 9.8 6.1 7.4 9.8 1.8 1 0 0 1 1 1 0 Dehydrin MFS_1 PF07690.16 OAP56666.1 - 3.1e-29 102.0 31.0 4.9e-22 78.3 13.1 2.7 3 0 0 3 3 3 2 Major Facilitator Superfamily Peptidase_U4 PF03419.13 OAP56666.1 - 2 7.6 10.5 5.9 6.1 0.2 2.8 2 1 0 2 2 2 0 Sporulation factor SpoIIGA Fungal_trans PF04082.18 OAP56667.1 - 6.7e-20 71.2 3.4 1.7e-19 69.9 3.4 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP56667.1 - 2.4e-05 24.4 12.1 5e-05 23.3 12.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_zinc_N PF00107.26 OAP56668.1 - 3.2e-25 88.6 0.0 5.1e-25 88.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAP56668.1 - 2.9e-15 57.5 0.0 4.5e-15 56.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAP56668.1 - 3.9e-09 36.3 0.0 6.6e-08 32.4 0.0 2.8 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 OAP56668.1 - 0.00086 19.2 0.0 0.0017 18.2 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase adh_short PF00106.25 OAP56668.1 - 0.24 10.8 1.0 0.37 10.2 0.8 1.4 1 1 0 1 1 1 0 short chain dehydrogenase FAA_hydrolase PF01557.18 OAP56669.1 - 0.00015 21.5 0.0 0.00018 21.2 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Vac7 PF12751.7 OAP56670.1 - 0.012 15.1 5.3 0.016 14.7 5.3 1.0 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 TFIIF_alpha PF05793.12 OAP56670.1 - 0.052 12.1 10.7 0.069 11.7 10.7 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nop53 PF07767.11 OAP56670.1 - 0.17 11.2 11.6 0.043 13.2 3.6 2.0 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) Epimerase PF01370.21 OAP56671.1 - 2.6e-10 40.2 0.0 4.8e-10 39.3 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 OAP56671.1 - 0.00019 20.6 0.0 0.0015 17.7 0.0 2.0 2 0 0 2 2 2 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 OAP56671.1 - 0.0047 16.8 0.0 0.0087 16.0 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 OAP56671.1 - 0.0096 15.1 0.1 0.066 12.4 0.0 2.0 2 0 0 2 2 2 1 Male sterility protein GDP_Man_Dehyd PF16363.5 OAP56671.1 - 0.048 13.1 0.0 0.091 12.1 0.0 1.5 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase NmrA PF05368.13 OAP56671.1 - 0.048 13.2 0.0 0.074 12.6 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family adh_short PF00106.25 OAP56671.1 - 0.064 12.7 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase DUF410 PF04190.13 OAP56672.1 - 2.4e-81 273.3 0.0 2.9e-81 273.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF410) TPR_20 PF14561.6 OAP56672.1 - 0.13 12.6 0.0 1 9.7 0.0 2.3 2 1 0 2 2 2 0 Tetratricopeptide repeat Response_reg PF00072.24 OAP56673.1 - 7.5e-20 71.2 0.0 6.1e-14 52.1 0.0 2.3 2 0 0 2 2 2 2 Response regulator receiver domain SURF2 PF05477.11 OAP56673.1 - 0.3 10.8 8.1 0.49 10.0 8.1 1.3 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) RRM_1 PF00076.22 OAP56674.1 - 2.3e-16 59.4 0.0 1.4e-13 50.4 0.0 2.7 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OAP56674.1 - 0.082 12.8 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Occluded RNA-recognition motif UBA_4 PF14555.6 OAP56675.1 - 8.8e-10 38.2 0.0 2.9e-09 36.6 0.0 1.9 2 0 0 2 2 2 1 UBA-like domain PI3K_P85_iSH2 PF16454.5 OAP56675.1 - 0.37 10.4 3.8 1.9 8.0 0.1 2.5 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Pkinase PF00069.25 OAP56676.1 - 1.8e-58 198.0 0.0 3e-58 197.3 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP56676.1 - 5.9e-23 81.5 0.0 1.1e-13 51.0 0.0 2.8 2 1 1 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.6 OAP56676.1 - 0.043 13.1 0.3 3.1 7.0 0.0 2.4 2 0 0 2 2 2 0 Kinase-like Haspin_kinase PF12330.8 OAP56676.1 - 0.044 12.7 0.0 0.058 12.3 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 OAP56676.1 - 0.053 12.6 0.0 0.92 8.5 0.0 1.9 2 0 0 2 2 2 0 Seadornavirus VP7 Choline_kinase PF01633.20 OAP56676.1 - 0.13 11.8 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Gly_transf_sug PF04488.15 OAP56677.1 - 5.2e-14 52.7 0.0 1.8e-13 51.0 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif VASt PF16016.5 OAP56678.1 - 5e-37 127.7 0.0 9.2e-37 126.8 0.0 1.4 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 OAP56678.1 - 4.1e-22 78.2 0.0 1.1e-21 76.8 0.0 1.8 1 0 0 1 1 1 1 GRAM domain DUF4065 PF13274.6 OAP56678.1 - 3.9 8.4 5.2 4.8 8.1 1.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4065) MPS2 PF17060.5 OAP56679.1 - 0.056 12.7 0.1 0.096 11.9 0.1 1.2 1 0 0 1 1 1 0 Monopolar spindle protein 2 Mg_trans_NIPA PF05653.14 OAP56680.1 - 1.5e-65 221.2 6.4 2.4e-64 217.3 3.8 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 OAP56680.1 - 0.0024 18.0 0.7 0.0024 18.0 0.7 3.9 3 1 1 4 4 4 1 EamA-like transporter family BaxI_1 PF12811.7 OAP56680.1 - 0.051 13.1 3.6 0.13 11.8 3.6 1.6 1 0 0 1 1 1 0 Bax inhibitor 1 like SLC35F PF06027.12 OAP56680.1 - 0.061 12.8 0.0 0.061 12.8 0.0 2.4 2 0 0 2 2 2 0 Solute carrier family 35 Trp_oprn_chp PF09534.10 OAP56680.1 - 0.22 11.3 1.5 3.5 7.4 0.9 2.7 2 1 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF3431 PF11913.8 OAP56681.1 - 2.1e-80 269.5 0.4 2.5e-80 269.3 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Glyco_hydro_47 PF01532.20 OAP56682.1 - 2.2e-148 495.0 0.0 2.5e-148 494.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 GlcNAc_2-epim PF07221.11 OAP56682.1 - 0.078 12.2 0.1 1.3 8.2 0.0 2.5 3 0 0 3 3 3 0 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) RRM_1 PF00076.22 OAP56683.1 - 4.6e-18 64.8 0.0 6.8e-18 64.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 OAP56683.1 - 2.9e-07 30.9 6.6 2.9e-07 30.9 6.6 3.6 2 1 1 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 Abhydrolase_3 PF07859.13 OAP56684.1 - 7.5e-42 143.6 0.0 1e-41 143.1 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 OAP56684.1 - 0.16 10.8 0.0 0.36 9.6 0.0 1.6 1 1 0 1 1 1 0 Carboxylesterase family WD40 PF00400.32 OAP56685.1 - 6.7e-13 48.9 16.3 0.00037 21.2 0.1 6.0 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAP56685.1 - 0.036 14.3 0.1 17 5.8 0.0 3.3 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Glyoxal_oxid_N PF07250.11 OAP56685.1 - 0.07 12.3 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Glyoxal oxidase N-terminus MIP PF00230.20 OAP56686.1 - 1.9e-53 181.5 3.5 2.4e-53 181.2 3.5 1.1 1 0 0 1 1 1 1 Major intrinsic protein OsmC PF02566.19 OAP56687.1 - 4.9e-19 68.7 0.0 8e-19 68.0 0.0 1.3 1 0 0 1 1 1 1 OsmC-like protein CVNH PF08881.10 OAP56688.1 - 1.2e-27 96.6 0.8 2.3e-27 95.6 0.8 1.5 1 0 0 1 1 1 1 CVNH domain Rick_17kDa_Anti PF05433.15 OAP56688.1 - 2e-05 24.3 12.4 2e-05 24.3 12.4 2.2 2 0 0 2 2 2 1 Glycine zipper 2TM domain PAP_PilO PF06864.12 OAP56688.1 - 0.0016 17.4 0.9 0.0023 16.8 0.9 1.2 1 0 0 1 1 1 1 Pilin accessory protein (PilO) Dehydrin PF00257.19 OAP56688.1 - 0.006 17.1 5.2 0.006 17.1 5.2 2.3 1 1 1 2 2 1 1 Dehydrin Gly-zipper_Omp PF13488.6 OAP56688.1 - 0.0068 16.4 10.4 0.0068 16.4 10.4 2.3 2 0 0 2 2 2 1 Glycine zipper Zip PF02535.22 OAP56688.1 - 0.011 15.0 2.9 0.016 14.5 2.9 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF533 PF04391.12 OAP56688.1 - 0.016 14.8 20.5 0.038 13.5 2.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF533) ABA_WDS PF02496.16 OAP56688.1 - 0.022 15.2 16.0 0.037 14.5 2.0 3.3 2 1 1 3 3 3 0 ABA/WDS induced protein DUF3824 PF12868.7 OAP56688.1 - 0.023 15.3 2.6 0.023 15.3 2.6 4.7 1 1 4 5 5 3 0 Domain of unknwon function (DUF3824) RskA PF10099.9 OAP56688.1 - 0.084 13.2 9.0 0.27 11.5 9.0 1.9 1 1 0 1 1 1 0 Anti-sigma-K factor rskA RR_TM4-6 PF06459.12 OAP56688.1 - 0.13 12.1 2.9 0.24 11.2 2.9 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TAF4 PF05236.14 OAP56688.1 - 0.43 10.3 8.2 0.57 9.9 8.2 1.1 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family PNISR PF15996.5 OAP56688.1 - 1.1 9.5 10.8 1.9 8.8 10.8 1.3 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR Presenilin PF01080.17 OAP56688.1 - 1.1 7.9 8.3 1.6 7.4 8.3 1.1 1 0 0 1 1 1 0 Presenilin UCR_TM PF02921.14 OAP56688.1 - 2 8.9 4.5 0.4 11.2 0.6 1.9 2 0 0 2 2 1 0 Ubiquinol cytochrome reductase transmembrane region Velvet PF11754.8 OAP56688.1 - 5.9 6.7 12.4 0.62 9.9 4.6 2.2 2 0 0 2 2 2 0 Velvet factor NAD_kinase PF01513.21 OAP56690.1 - 1.3e-51 175.6 0.0 1.9e-51 175.0 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 OAP56690.1 - 0.0013 18.3 0.0 0.0026 17.3 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Acyltransferase PF01553.21 OAP56691.1 - 4.7e-26 91.0 0.0 7.6e-26 90.3 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 OAP56691.1 - 5.6e-13 48.8 0.0 1.2e-12 47.7 0.0 1.6 1 0 0 1 1 1 1 Acyltransferase C-terminus Sulfotransfer_4 PF17784.1 OAP56692.1 - 5.8e-47 160.3 0.8 6.8e-47 160.1 0.8 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OAP56692.1 - 4e-05 24.1 0.2 0.0079 16.6 0.2 2.1 1 1 0 1 1 1 1 Sulfotransferase family Glyco_hydro_88 PF07470.13 OAP56693.1 - 0.14 11.2 0.1 0.98 8.4 0.0 2.0 2 0 0 2 2 2 0 Glycosyl Hydrolase Family 88 Sod_Cu PF00080.20 OAP56694.1 - 1e-47 161.9 6.6 1.2e-47 161.7 6.6 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) CRAL_TRIO PF00650.20 OAP56695.1 - 1.4e-21 76.9 0.0 2.1e-21 76.3 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 OAP56695.1 - 2.1e-05 24.6 0.0 6.2e-05 23.1 0.0 1.9 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain NADH_B2 PF14813.6 OAP56696.1 - 0.019 14.7 0.0 0.021 14.6 0.0 1.1 1 0 0 1 1 1 0 NADH dehydrogenase 1 beta subcomplex subunit 2 P5-ATPase PF12409.8 OAP56697.1 - 8.8e-36 122.8 0.4 1.9e-35 121.7 0.4 1.6 1 0 0 1 1 1 1 P5-type ATPase cation transporter E1-E2_ATPase PF00122.20 OAP56697.1 - 2e-28 99.1 0.0 4.9e-28 97.9 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 OAP56697.1 - 9.8e-15 55.4 0.7 4e-06 27.3 0.0 3.3 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 OAP56697.1 - 6.3e-06 26.2 0.0 1.7e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_C PF00689.21 OAP56697.1 - 7.5e-05 22.5 4.8 7.5e-05 22.5 4.8 2.6 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase_N PF00690.26 OAP56697.1 - 0.0043 16.7 0.0 0.0088 15.7 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 OAP56697.1 - 0.049 13.4 0.0 6.2 6.5 0.0 2.3 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase NAP PF00956.18 OAP56698.1 - 4.1e-96 321.3 9.4 4.1e-96 321.3 9.4 1.7 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) RNA_pol_3_Rpc31 PF11705.8 OAP56698.1 - 4.1 7.6 31.4 0.26 11.5 15.7 2.4 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 DUF4611 PF15387.6 OAP56698.1 - 6.5 7.0 20.1 14 5.9 8.9 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Myosin_head PF00063.21 OAP56699.1 - 3.5e-262 871.5 1.6 4.9e-262 871.1 1.6 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) DIL PF01843.19 OAP56699.1 - 3.2e-26 91.6 2.6 3.2e-26 91.6 2.6 2.5 2 0 0 2 2 1 1 DIL domain IQ PF00612.27 OAP56699.1 - 6.8e-10 37.9 32.5 0.0019 17.8 0.2 6.8 7 0 0 7 7 6 4 IQ calmodulin-binding motif GAS PF13851.6 OAP56699.1 - 4.8e-05 22.8 26.6 0.0033 16.8 13.6 2.8 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding AAA_16 PF13191.6 OAP56699.1 - 0.0033 17.8 0.8 0.012 16.0 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain FlaC_arch PF05377.11 OAP56699.1 - 0.022 15.1 8.7 2.9 8.3 0.3 4.2 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) PhoH PF02562.16 OAP56699.1 - 0.031 13.7 0.4 5.9 6.3 0.1 4.1 4 1 0 4 4 4 0 PhoH-like protein AAA_22 PF13401.6 OAP56699.1 - 0.061 13.6 0.1 0.061 13.6 0.1 2.7 2 1 0 2 2 2 0 AAA domain KASH_CCD PF14662.6 OAP56699.1 - 0.072 12.9 26.8 0.011 15.6 8.0 2.9 1 1 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH NACHT PF05729.12 OAP56699.1 - 0.11 12.4 0.1 0.36 10.7 0.1 1.9 1 0 0 1 1 1 0 NACHT domain Phage_GP20 PF06810.11 OAP56699.1 - 0.27 11.0 10.7 1.7 8.4 1.2 2.8 1 1 1 2 2 2 0 Phage minor structural protein GP20 ERM PF00769.19 OAP56699.1 - 0.31 10.8 20.2 1.1 9.0 20.2 2.0 1 0 0 1 1 1 0 Ezrin/radixin/moesin family APG6_N PF17675.1 OAP56699.1 - 0.56 10.7 34.8 1.8 9.1 8.7 3.7 2 1 1 3 3 3 0 Apg6 coiled-coil region ATG16 PF08614.11 OAP56699.1 - 0.58 10.3 29.6 19 5.4 8.5 2.8 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Spc7 PF08317.11 OAP56699.1 - 0.6 8.9 25.3 0.57 9.0 9.9 2.4 1 1 1 2 2 2 0 Spc7 kinetochore protein Cep57_CLD PF14073.6 OAP56699.1 - 0.67 9.9 23.4 1.7 8.6 23.4 1.7 1 0 0 1 1 1 0 Centrosome localisation domain of Cep57 Prefoldin PF02996.17 OAP56699.1 - 0.89 9.5 7.9 9.3 6.2 0.3 3.4 2 1 0 2 2 2 0 Prefoldin subunit ABC_tran PF00005.27 OAP56699.1 - 1.1 9.8 0.0 1.1 9.8 0.0 3.1 2 1 0 2 2 1 0 ABC transporter DUF4201 PF13870.6 OAP56699.1 - 2.1 8.1 20.6 2.4 7.9 5.1 3.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) DegQ PF08181.11 OAP56699.1 - 4.2 7.6 11.7 0.049 13.7 1.6 3.1 4 0 0 4 4 2 0 DegQ (SacQ) family Fez1 PF06818.15 OAP56699.1 - 5.3 7.4 21.4 12 6.3 7.6 2.5 1 1 1 2 2 2 0 Fez1 Snapin_Pallidin PF14712.6 OAP56699.1 - 5.5 7.5 19.5 1.8 9.0 6.2 4.2 3 1 1 4 4 4 0 Snapin/Pallidin zf-C4H2 PF10146.9 OAP56699.1 - 6.1 7.1 13.2 3.6 7.9 9.3 2.5 1 1 1 2 2 2 0 Zinc finger-containing protein FUSC PF04632.12 OAP56699.1 - 7 5.1 7.9 14 4.0 7.9 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family HpcH_HpaI PF03328.14 OAP56702.1 - 3.7e-34 117.8 0.0 4.7e-34 117.5 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family Nudix_hydro PF18290.1 OAP56702.1 - 0.023 14.7 0.0 0.11 12.4 0.0 2.0 2 0 0 2 2 2 0 Nudix hydrolase domain PEP-utilizers_C PF02896.18 OAP56702.1 - 0.075 12.1 0.2 2.3 7.2 0.0 2.4 2 1 0 2 2 2 0 PEP-utilising enzyme, TIM barrel domain TauD PF02668.16 OAP56703.1 - 5.6e-55 187.0 1.1 6.6e-55 186.8 1.1 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family PPR_3 PF13812.6 OAP56703.1 - 0.17 12.0 0.1 0.41 10.8 0.1 1.6 1 0 0 1 1 1 0 Pentatricopeptide repeat domain FMN_dh PF01070.18 OAP56704.1 - 1.9e-119 398.8 0.0 2.2e-119 398.6 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 OAP56704.1 - 0.0003 20.0 0.0 0.00061 19.0 0.0 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 OAP56704.1 - 0.0018 17.3 0.3 0.0079 15.2 0.2 2.0 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain DHO_dh PF01180.21 OAP56704.1 - 0.0025 17.1 0.3 0.46 9.7 0.0 2.2 2 0 0 2 2 2 2 Dihydroorotate dehydrogenase AP_endonuc_2 PF01261.24 OAP56704.1 - 0.012 15.0 0.0 0.56 9.6 0.0 2.3 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel NMO PF03060.15 OAP56704.1 - 0.045 13.1 0.1 0.066 12.6 0.1 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase Fungal_trans PF04082.18 OAP56705.1 - 8e-14 51.3 0.2 1.5e-13 50.4 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain AAA_18 PF13238.6 OAP56706.1 - 1.9e-24 86.7 0.0 4.2e-24 85.6 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 OAP56706.1 - 7.3e-09 36.2 0.0 2.4e-08 34.5 0.0 1.8 1 1 1 2 2 2 1 AAA domain NTPase_1 PF03266.15 OAP56706.1 - 0.0017 18.3 0.5 0.0036 17.2 0.5 1.6 1 0 0 1 1 1 1 NTPase AAA PF00004.29 OAP56706.1 - 0.0035 17.8 0.0 0.0055 17.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OAP56706.1 - 0.0038 17.5 0.0 0.0062 16.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 OAP56706.1 - 0.0045 17.3 0.0 0.0086 16.5 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_28 PF13521.6 OAP56706.1 - 0.0089 16.3 2.0 0.013 15.8 0.7 1.8 2 0 0 2 2 2 1 AAA domain KTI12 PF08433.10 OAP56706.1 - 0.029 13.8 0.0 0.041 13.3 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_24 PF13479.6 OAP56706.1 - 0.034 13.8 1.9 0.072 12.8 1.1 2.0 1 1 1 2 2 2 0 AAA domain T2SSE PF00437.20 OAP56706.1 - 0.045 12.8 0.0 0.32 10.0 0.1 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 OAP56706.1 - 0.053 12.9 1.2 0.094 12.1 0.2 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family SRP54 PF00448.22 OAP56706.1 - 0.065 12.9 0.1 0.12 12.0 0.1 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_16 PF13191.6 OAP56706.1 - 0.071 13.5 0.3 0.062 13.7 0.3 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.6 OAP56706.1 - 0.087 12.9 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 OAP56706.1 - 0.091 12.3 0.8 0.73 9.4 0.1 2.2 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 OAP56706.1 - 0.091 12.7 0.0 0.21 11.5 0.0 1.6 2 0 0 2 2 1 0 NACHT domain Mg_chelatase PF01078.21 OAP56706.1 - 0.1 12.0 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI MMR_HSR1 PF01926.23 OAP56706.1 - 0.12 12.4 0.2 0.17 12.0 0.2 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_19 PF13245.6 OAP56706.1 - 0.13 12.6 2.9 0.11 12.8 1.5 1.6 1 1 0 1 1 1 0 AAA domain Microtub_bd PF16796.5 OAP56706.1 - 0.14 12.1 0.0 0.92 9.4 0.0 1.9 2 0 0 2 2 2 0 Microtubule binding AAA_30 PF13604.6 OAP56706.1 - 0.21 11.3 0.6 0.39 10.4 0.5 1.5 1 1 0 1 1 1 0 AAA domain CbiA PF01656.23 OAP56706.1 - 0.56 10.3 2.2 1.5 8.9 1.9 1.8 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Ham1p_like PF01725.16 OAP56707.1 - 1.4e-55 188.1 0.0 1.6e-55 187.9 0.0 1.0 1 0 0 1 1 1 1 Ham1 family Peptidase_C78 PF07910.13 OAP56708.1 - 1.9e-60 203.9 0.0 2.6e-60 203.5 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C78 zf-Di19 PF05605.12 OAP56708.1 - 0.0042 17.4 0.6 0.032 14.5 0.1 2.4 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.6 OAP56708.1 - 0.13 12.1 1.4 0.16 11.7 0.0 1.9 2 0 0 2 2 2 0 C2H2-type zinc-finger domain AA_kinase PF00696.28 OAP56709.1 - 2.2e-44 151.9 0.0 3.2e-44 151.3 0.0 1.3 1 0 0 1 1 1 1 Amino acid kinase family ACT_7 PF13840.6 OAP56709.1 - 2.6e-11 43.1 1.8 4.5e-10 39.2 0.3 2.5 2 0 0 2 2 2 1 ACT domain ACT PF01842.25 OAP56709.1 - 1.4e-07 31.2 0.1 1.2e-06 28.2 0.1 2.4 2 0 0 2 2 2 1 ACT domain Forkhead PF00250.18 OAP56710.1 - 4.5e-34 116.6 0.2 8.2e-34 115.7 0.2 1.5 1 0 0 1 1 1 1 Forkhead domain Dyp_perox PF04261.12 OAP56711.1 - 3.9e-89 298.9 0.0 4.8e-89 298.6 0.0 1.1 1 0 0 1 1 1 1 Dyp-type peroxidase family AlcCBM31 PF11606.8 OAP56711.1 - 0.038 14.2 0.0 0.09 13.0 0.0 1.5 1 0 0 1 1 1 0 Family 31 carbohydrate binding protein Ribosomal_S10 PF00338.22 OAP56712.1 - 1e-26 93.0 0.0 2.3e-26 91.9 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e GMC_oxred_N PF00732.19 OAP56713.1 - 2.7e-63 214.1 0.0 4e-63 213.6 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAP56713.1 - 2.6e-36 125.3 0.0 4.1e-36 124.7 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 OAP56713.1 - 1.5e-05 24.3 0.0 0.019 14.1 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 OAP56713.1 - 0.00036 20.2 3.0 0.058 13.0 2.8 3.1 2 1 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 OAP56713.1 - 0.026 13.6 0.0 0.06 12.4 0.1 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_8 PF13450.6 OAP56713.1 - 0.039 14.2 0.0 0.096 12.9 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAP56713.1 - 0.06 12.6 0.2 0.46 9.7 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 OAP56713.1 - 0.066 13.5 0.0 0.24 11.6 0.0 1.9 2 0 0 2 2 2 0 TrkA-N domain Thi4 PF01946.17 OAP56713.1 - 0.097 11.9 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 Thi4 family GDI PF00996.18 OAP56713.1 - 0.21 10.1 0.0 0.33 9.4 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor tRNA-synt_1b PF00579.25 OAP56714.1 - 8.5e-67 225.5 0.0 1.1e-66 225.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Abhydrolase_1 PF00561.20 OAP56715.1 - 4.1e-25 88.9 0.0 2e-18 67.0 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAP56715.1 - 5.9e-15 56.5 0.1 8.6e-15 55.9 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAP56715.1 - 4.8e-12 45.6 0.1 1.6e-11 43.9 0.1 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 OAP56715.1 - 2.1e-08 34.6 0.0 3.3e-08 33.9 0.0 1.3 1 1 0 1 1 1 1 Thioesterase domain Esterase PF00756.20 OAP56715.1 - 5.2e-05 23.0 0.0 8.9e-05 22.2 0.0 1.5 1 1 0 1 1 1 1 Putative esterase PGAP1 PF07819.13 OAP56715.1 - 0.0009 19.0 0.2 0.081 12.6 0.1 2.4 1 1 1 2 2 2 1 PGAP1-like protein Chlorophyllase2 PF12740.7 OAP56715.1 - 0.017 14.0 0.0 0.029 13.3 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Lipase_3 PF01764.25 OAP56715.1 - 0.026 14.4 0.0 0.047 13.6 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Ndr PF03096.14 OAP56715.1 - 0.096 11.4 0.0 0.2 10.3 0.0 1.4 2 0 0 2 2 2 0 Ndr family Ribosomal_S3Ae PF01015.18 OAP56716.1 - 1.5e-89 298.9 2.8 1.8e-89 298.7 2.8 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family SUI1 PF01253.22 OAP56716.1 - 0.008 16.7 0.3 0.081 13.5 0.0 2.3 2 0 0 2 2 2 1 Translation initiation factor SUI1 Ribosomal_L22 PF00237.19 OAP56716.1 - 0.1 12.9 0.2 0.18 12.0 0.2 1.4 1 0 0 1 1 1 0 Ribosomal protein L22p/L17e Abhydro_lipase PF04083.16 OAP56716.1 - 0.18 11.4 0.0 0.36 10.4 0.0 1.5 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region tRNA-synt_2b PF00587.25 OAP56717.1 - 1.3e-34 119.7 0.0 2.4e-34 118.9 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 OAP56717.1 - 6.3e-13 48.9 5.4 6.3e-13 48.9 5.4 1.9 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain DUF5082 PF16888.5 OAP56717.1 - 0.019 15.2 3.3 0.047 14.0 3.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) DUF4088 PF13317.6 OAP56717.1 - 0.022 14.3 0.5 0.035 13.7 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4088) Cytochrom_C552 PF02335.15 OAP56717.1 - 0.28 10.1 6.5 0.11 11.4 0.1 2.1 2 0 0 2 2 2 0 Cytochrome c552 Ras PF00071.22 OAP56718.1 - 9.3e-48 161.9 0.3 1.1e-47 161.7 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAP56718.1 - 1.4e-15 57.5 0.0 2.2e-15 57.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAP56718.1 - 1.7e-08 34.1 0.0 1.9e-08 34.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OAP56718.1 - 1.1e-05 25.0 0.3 7.3e-05 22.4 0.1 1.9 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 OAP56718.1 - 3.5e-05 23.3 0.1 6.2e-05 22.5 0.1 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 OAP56718.1 - 0.00015 21.7 0.2 0.035 14.0 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OAP56718.1 - 0.00059 19.9 0.0 0.00085 19.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OAP56718.1 - 0.00077 19.0 0.1 0.007 15.9 0.1 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B zf_ZIC PF18366.1 OAP56718.1 - 0.085 13.0 0.0 0.24 11.5 0.0 1.8 1 0 0 1 1 1 0 Zic proteins zinc finger domain WAPL PF07814.13 OAP56719.1 - 1.2e-35 123.1 9.4 1.9e-35 122.4 9.4 1.3 1 0 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin DUF3453 PF11935.8 OAP56719.1 - 0.22 11.1 3.0 3.1 7.4 0.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3453) UPRTase PF14681.6 OAP56720.1 - 3.1e-79 265.2 0.0 3.9e-79 264.9 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 OAP56720.1 - 0.00065 19.3 0.0 0.00096 18.7 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain 2-Hacid_dh_C PF02826.19 OAP56721.1 - 6.1e-52 175.5 0.0 1e-51 174.8 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 OAP56721.1 - 4.7e-37 126.6 0.0 7.1e-37 126.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ACT PF01842.25 OAP56721.1 - 0.00081 19.1 0.1 0.0018 18.0 0.1 1.7 1 0 0 1 1 1 1 ACT domain NAD_binding_2 PF03446.15 OAP56721.1 - 0.00085 19.5 0.1 0.0025 18.0 0.1 1.8 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 OAP56721.1 - 0.057 13.0 0.1 0.3 10.6 0.0 2.1 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain AdoHcyase_NAD PF00670.21 OAP56721.1 - 0.06 13.4 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain XdhC_C PF13478.6 OAP56721.1 - 0.11 13.0 0.3 0.38 11.3 0.0 2.0 3 0 0 3 3 3 0 XdhC Rossmann domain DUF1780 PF08682.10 OAP56721.1 - 0.15 11.8 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 Putative endonuclease, protein of unknown function (DUF1780) PD40 PF07676.12 OAP56722.1 - 0.11 12.5 0.1 1.3 9.1 0.0 2.7 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Ribosomal_L19e PF01280.20 OAP56723.1 - 8.3e-62 207.5 7.8 8.3e-62 207.5 7.8 1.8 2 0 0 2 2 2 1 Ribosomal protein L19e TRAP-gamma PF07074.12 OAP56723.1 - 1.1 8.7 4.4 1.6 8.2 4.4 1.2 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) KilA-N PF04383.13 OAP56724.1 - 0.00028 20.7 0.0 0.0042 16.9 0.0 2.2 1 1 0 1 1 1 1 KilA-N domain Elf1 PF05129.13 OAP56725.1 - 1.2e-29 102.2 0.7 1.5e-29 101.9 0.7 1.1 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like EST1_DNA_bind PF10373.9 OAP56725.1 - 0.0068 15.9 0.0 0.0084 15.6 0.0 1.1 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain zf-Sec23_Sec24 PF04810.15 OAP56725.1 - 0.052 13.6 0.8 3.6 7.7 0.1 2.2 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger GTP_CH_N PF12471.8 OAP56726.1 - 3.2e-92 307.6 0.0 4.6e-92 307.1 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.20 OAP56726.1 - 3.9e-17 62.3 0.0 6.8e-17 61.5 0.0 1.4 1 0 0 1 1 1 1 GTP cyclohydrolase II HCR PF07111.12 OAP56726.1 - 0.081 11.0 0.0 0.11 10.5 0.0 1.1 1 0 0 1 1 1 0 Alpha helical coiled-coil rod protein (HCR) DUF4672 PF15716.5 OAP56727.1 - 0.046 13.3 0.1 0.077 12.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4672) SHMT PF00464.19 OAP56728.1 - 6.9e-198 657.2 0.0 8e-198 656.9 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase AMP-binding PF00501.28 OAP56730.1 - 2.3e-75 253.8 0.0 3.1e-75 253.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 OAP56730.1 - 5.1e-19 67.9 1.9 9.7e-19 67.0 0.7 2.2 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 OAP56730.1 - 6.4e-16 59.1 0.0 2.1e-15 57.5 0.0 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Glyco_tranf_2_3 PF13641.6 OAP56730.1 - 0.09 12.6 0.1 3 7.7 0.0 2.3 2 0 0 2 2 2 0 Glycosyltransferase like family 2 AdoMet_MTase PF07757.13 OAP56731.1 - 4.2e-35 120.4 0.0 7.1e-35 119.7 0.0 1.3 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_32 PF13679.6 OAP56731.1 - 0.08 12.9 0.0 1.2 9.1 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Sec34 PF04136.15 OAP56732.1 - 1.6e-48 164.4 2.0 1.6e-48 164.4 2.0 1.9 2 0 0 2 2 2 1 Sec34-like family Bep_C_terminal PF17841.1 OAP56732.1 - 0.0042 17.3 1.3 0.42 10.8 0.0 3.1 3 0 0 3 3 3 1 BID domain of Bartonella effector protein (Bep) COG6 PF06419.11 OAP56732.1 - 0.058 11.6 3.7 0.063 11.5 0.6 2.3 3 0 0 3 3 3 0 Conserved oligomeric complex COG6 ALIX_LYPXL_bnd PF13949.6 OAP56732.1 - 2.1 7.6 7.7 0.91 8.8 3.0 2.4 3 0 0 3 3 3 0 ALIX V-shaped domain binding to HIV RCC1 PF00415.18 OAP56733.1 - 2.4e-27 95.3 6.4 4.6e-07 30.3 0.0 7.6 6 1 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OAP56733.1 - 1.3e-11 44.0 25.4 8.5e-09 35.0 0.0 6.5 8 0 0 8 8 8 3 Regulator of chromosome condensation (RCC1) repeat RskA PF10099.9 OAP56733.1 - 0.072 13.4 4.7 0.12 12.6 4.7 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA ASF1_hist_chap PF04729.13 OAP56734.1 - 1.4e-72 242.7 0.0 2.4e-72 241.9 0.0 1.4 1 0 0 1 1 1 1 ASF1 like histone chaperone Nop14 PF04147.12 OAP56734.1 - 0.0023 16.3 30.2 0.0029 15.9 30.2 1.0 1 0 0 1 1 1 1 Nop14-like family Nop53 PF07767.11 OAP56734.1 - 0.77 9.1 19.2 0.96 8.8 19.2 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) TFIIA PF03153.13 OAP56734.1 - 2.5 8.0 18.6 3.1 7.7 18.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit BUD22 PF09073.10 OAP56734.1 - 7.5 5.8 26.7 9.7 5.4 26.7 1.1 1 0 0 1 1 1 0 BUD22 PPP4R2 PF09184.11 OAP56734.1 - 7.6 6.0 19.7 11 5.5 19.7 1.3 1 0 0 1 1 1 0 PPP4R2 Suf PF05843.14 OAP56735.1 - 1.8e-79 267.8 0.0 1.8e-79 267.8 0.0 4.0 6 0 0 6 6 6 2 Suppressor of forked protein (Suf) TPR_14 PF13428.6 OAP56735.1 - 9.9e-06 26.0 1.0 0.016 16.0 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat Spexin PF15171.6 OAP56735.1 - 0.034 14.3 0.0 0.095 12.9 0.0 1.7 1 0 0 1 1 1 0 Neuropeptide secretory protein family, NPQ, spexin Piwi PF02171.17 OAP56736.1 - 5.2e-69 232.8 0.0 7.5e-69 232.3 0.0 1.2 1 0 0 1 1 1 1 Piwi domain ArgoL1 PF08699.10 OAP56736.1 - 1.3e-19 69.6 0.0 2.9e-19 68.5 0.0 1.6 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoN PF16486.5 OAP56736.1 - 6.8e-17 62.4 0.1 2.7e-16 60.4 0.0 2.0 2 0 0 2 2 2 1 N-terminal domain of argonaute PAZ PF02170.22 OAP56736.1 - 7e-14 51.8 0.1 1.3e-13 50.9 0.1 1.4 1 0 0 1 1 1 1 PAZ domain ArgoL2 PF16488.5 OAP56736.1 - 1.4e-11 44.5 0.0 3.6e-11 43.2 0.0 1.8 1 0 0 1 1 1 1 Argonaute linker 2 domain ArgoMid PF16487.5 OAP56736.1 - 1.2e-06 28.7 0.0 3.1e-06 27.4 0.0 1.8 1 0 0 1 1 1 1 Mid domain of argonaute DUF2834 PF11196.8 OAP56737.1 - 0.012 15.9 1.2 0.021 15.2 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2834) DUF5134 PF17197.4 OAP56737.1 - 0.034 14.1 0.5 0.044 13.7 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5134) p450 PF00067.22 OAP56739.1 - 2e-59 201.6 0.0 2.6e-59 201.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_7 PF03441.14 OAP56740.1 - 7.8e-47 159.4 0.0 1.2e-46 158.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 OAP56740.1 - 6.6e-19 68.5 0.0 1.4e-18 67.5 0.0 1.5 1 0 0 1 1 1 1 DNA photolyase zf-C2H2 PF00096.26 OAP56741.1 - 1.1e-11 44.5 11.0 7.6e-06 26.1 0.7 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAP56741.1 - 3.2e-09 36.8 9.2 0.00023 21.8 0.7 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OAP56741.1 - 1.6e-07 31.5 11.0 5.3e-06 26.6 2.2 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-H2C2_5 PF13909.6 OAP56741.1 - 5.8e-05 22.7 7.8 0.0074 16.0 0.2 2.5 2 0 0 2 2 2 2 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 OAP56741.1 - 0.00027 21.2 3.5 0.0073 16.6 0.1 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2HE PF16278.5 OAP56741.1 - 0.0039 17.6 6.6 0.14 12.6 0.9 2.3 1 1 1 2 2 2 2 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_6 PF13912.6 OAP56741.1 - 0.029 14.4 9.3 0.4 10.7 0.5 2.7 3 0 0 3 3 3 0 C2H2-type zinc finger zf-met PF12874.7 OAP56741.1 - 0.33 11.4 0.2 0.33 11.4 0.2 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 OAP56741.1 - 0.43 10.4 3.6 5.7 6.8 0.3 2.5 2 0 0 2 2 2 0 zinc-finger C2H2-type zf_UBZ PF18439.1 OAP56741.1 - 2.5 7.7 5.5 8.7 6.0 0.2 3.0 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-AN1 PF01428.16 OAP56741.1 - 6.1 7.1 8.6 19 5.5 2.0 2.3 1 1 1 2 2 2 0 AN1-like Zinc finger DUF1687 PF07955.11 OAP56743.1 - 7.3e-30 104.1 0.1 1e-29 103.6 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1687) ArsC PF03960.15 OAP56743.1 - 0.014 15.4 0.0 0.031 14.3 0.0 1.5 2 0 0 2 2 2 0 ArsC family Glyco_hydro_76 PF03663.14 OAP56744.1 - 6.5e-158 526.0 11.3 7.5e-158 525.8 11.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 OAP56744.1 - 0.49 9.4 9.7 1.1 8.3 0.2 3.1 1 1 1 3 3 3 0 Glycosyl Hydrolase Family 88 CBP4 PF07960.11 OAP56745.1 - 1.3e-20 73.6 0.3 1.4e-20 73.4 0.3 1.1 1 0 0 1 1 1 1 CBP4 DPCD PF14913.6 OAP56745.1 - 0.00035 20.0 0.1 0.00044 19.7 0.1 1.1 1 0 0 1 1 1 1 DPCD protein family Synaptobrevin PF00957.21 OAP56746.1 - 2.3e-33 113.9 1.6 2.5e-33 113.7 1.6 1.0 1 0 0 1 1 1 1 Synaptobrevin AKNA PF12443.8 OAP56746.1 - 0.054 14.2 0.0 0.093 13.4 0.0 1.3 1 1 0 1 1 1 0 AT-hook-containing transcription factor MCU PF04678.13 OAP56746.1 - 0.12 12.4 0.0 0.15 12.2 0.0 1.0 1 0 0 1 1 1 0 Mitochondrial calcium uniporter DUF1035 PF06281.12 OAP56746.1 - 0.6 10.1 3.3 0.89 9.6 3.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1035) NAT PF04768.13 OAP56747.1 - 1.2e-51 174.8 0.1 2.4e-51 173.8 0.1 1.5 1 0 0 1 1 1 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase Semialdhyde_dh PF01118.24 OAP56747.1 - 3.1e-32 111.5 0.0 7.1e-32 110.4 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.28 OAP56747.1 - 1.3e-30 106.8 0.2 2.8e-30 105.7 0.0 1.6 2 0 0 2 2 2 1 Amino acid kinase family Sacchrp_dh_NADP PF03435.18 OAP56747.1 - 0.04 14.2 0.0 0.1 12.9 0.0 1.7 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DapB_N PF01113.20 OAP56747.1 - 0.042 14.0 0.0 0.16 12.1 0.0 2.1 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Rad21_Rec8_N PF04825.13 OAP56748.1 - 1.7e-21 76.4 0.0 3.1e-21 75.6 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 OAP56748.1 - 0.041 13.2 0.0 0.095 12.0 0.0 1.6 1 0 0 1 1 1 0 Conserved region of Rad21 / Rec8 like protein CEP19 PF14933.6 OAP56748.1 - 0.084 13.2 0.1 0.21 11.9 0.1 1.6 1 0 0 1 1 1 0 CEP19-like protein DUF3408 PF11888.8 OAP56748.1 - 0.21 11.7 0.9 0.51 10.5 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) Sel1 PF08238.12 OAP56749.1 - 9.9e-49 162.7 26.3 6.3e-08 33.1 0.1 8.1 8 0 0 8 8 8 7 Sel1 repeat TPR_17 PF13431.6 OAP56749.1 - 0.041 14.3 0.6 12 6.5 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 OAP56749.1 - 1 10.1 12.4 14 6.6 0.1 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 OAP56749.1 - 1.6 9.5 12.4 24 5.7 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat FAD_binding_3 PF01494.19 OAP56750.1 - 6.1e-62 209.9 0.3 7.6e-62 209.6 0.3 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 OAP56750.1 - 4.6e-06 26.8 0.0 1e-05 25.6 0.0 1.6 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Trp_halogenase PF04820.14 OAP56750.1 - 7.5e-05 21.8 0.0 0.00021 20.3 0.0 1.7 2 0 0 2 2 2 1 Tryptophan halogenase DAO PF01266.24 OAP56750.1 - 0.00035 20.3 0.1 0.00087 19.0 0.1 1.7 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 OAP56750.1 - 0.0037 16.7 0.1 0.0065 15.9 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 OAP56750.1 - 0.0037 16.5 0.0 0.0097 15.2 0.0 1.6 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 OAP56750.1 - 0.0042 16.4 0.0 0.011 15.0 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAP56750.1 - 0.011 15.1 0.0 0.017 14.4 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAP56750.1 - 0.013 14.6 0.0 0.023 13.8 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 OAP56750.1 - 0.014 15.9 0.0 0.04 14.5 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAP56750.1 - 0.032 14.5 0.0 0.097 12.9 0.0 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 OAP56750.1 - 0.054 12.2 0.1 0.14 10.8 0.0 1.6 2 0 0 2 2 2 0 HI0933-like protein MPC PF03650.13 OAP56751.1 - 1.9e-46 156.7 0.3 3.7e-46 155.8 0.3 1.4 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers MtN3_slv PF03083.16 OAP56751.1 - 0.0013 18.7 0.3 0.0022 18.0 0.3 1.4 1 0 0 1 1 1 1 Sugar efflux transporter for intercellular exchange L51_S25_CI-B8 PF05047.16 OAP56752.1 - 1.9e-15 56.5 0.0 2.4e-15 56.2 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain LigB PF02900.18 OAP56753.1 - 1.3e-36 126.0 0.2 1.7e-36 125.7 0.2 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Metallophos_C PF14008.6 OAP56753.1 - 0.15 13.0 0.4 0.45 11.4 0.1 2.0 2 0 0 2 2 2 0 Iron/zinc purple acid phosphatase-like protein C adh_short PF00106.25 OAP56754.1 - 2.6e-41 141.2 0.2 3.6e-41 140.8 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP56754.1 - 5.6e-31 107.9 0.3 7.8e-31 107.4 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP56754.1 - 1.5e-06 28.2 2.5 2.7e-05 24.2 2.5 2.1 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 OAP56754.1 - 0.00022 20.8 0.1 0.00044 19.8 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 OAP56754.1 - 0.0057 15.8 0.0 0.0091 15.1 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain ODR4-like PF14778.6 OAP56754.1 - 0.08 11.9 0.0 0.11 11.5 0.0 1.1 1 0 0 1 1 1 0 Olfactory receptor 4-like DUF3237 PF11578.8 OAP56755.1 - 6.2e-37 126.7 0.0 1e-36 126.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) zf-BED PF02892.15 OAP56755.1 - 0.0011 18.9 7.5 0.3 11.1 1.0 2.4 2 0 0 2 2 2 2 BED zinc finger PyrI_C PF02748.15 OAP56755.1 - 0.76 9.7 5.0 10 6.1 0.6 2.5 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain RRG8 PF17068.5 OAP56756.1 - 0.012 15.1 0.0 0.023 14.1 0.0 1.4 1 0 0 1 1 1 0 Required for respiratory growth protein 8 mitochondrial Abhydrolase_6 PF12697.7 OAP56757.1 - 9.4e-17 62.4 1.5 1.2e-16 62.0 1.5 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAP56757.1 - 9.6e-05 22.1 0.0 0.00017 21.4 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAP56757.1 - 0.00012 21.5 0.1 0.0018 17.6 0.1 2.2 1 1 0 1 1 1 1 Serine aminopeptidase, S33 SET PF00856.28 OAP56758.1 - 1.8e-18 67.5 0.0 4.9e-18 66.1 0.0 1.8 1 0 0 1 1 1 1 SET domain Gln-synt_C PF00120.24 OAP56759.1 - 2e-82 277.0 0.0 2.4e-82 276.7 0.0 1.0 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Viral_alk_exo PF01771.17 OAP56759.1 - 0.11 11.3 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Viral alkaline exonuclease adh_short_C2 PF13561.6 OAP56760.1 - 2.2e-60 204.1 0.0 2.5e-60 204.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP56760.1 - 6.9e-44 149.6 0.0 8.8e-44 149.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAP56760.1 - 3.6e-10 40.0 0.4 5.3e-10 39.5 0.4 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 OAP56760.1 - 0.0012 18.8 0.0 0.002 18.1 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_25 PF13649.6 OAP56760.1 - 0.0012 19.5 0.0 0.0027 18.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.21 OAP56760.1 - 0.0089 15.5 0.0 0.013 15.0 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 OAP56760.1 - 0.0096 15.8 0.5 0.033 14.1 0.1 1.9 2 1 0 2 2 2 1 NAD(P)H-binding Methyltransf_12 PF08242.12 OAP56760.1 - 0.11 13.2 0.1 0.87 10.4 0.1 2.2 1 1 0 1 1 1 0 Methyltransferase domain 3Beta_HSD PF01073.19 OAP56760.1 - 0.13 11.2 0.0 0.29 10.1 0.0 1.7 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family RecC_C PF17946.1 OAP56760.1 - 0.14 12.0 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 RecC C-terminal domain Proteasom_PSMB PF10508.9 OAP56762.1 - 9.9e-05 21.0 0.0 0.00014 20.5 0.0 1.2 1 0 0 1 1 1 1 Proteasome non-ATPase 26S subunit DUF2249 PF10006.9 OAP56762.1 - 0.07 13.0 0.5 0.72 9.8 0.1 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2249) TrmO_C PF18389.1 OAP56762.1 - 0.17 12.0 0.8 2 8.6 0.2 2.6 2 0 0 2 2 2 0 TrmO C-terminal domain MitMem_reg PF13012.6 OAP56763.1 - 1.5e-07 31.8 0.0 4.1e-07 30.4 0.0 1.7 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 OAP56763.1 - 6.5e-07 29.3 0.0 1.1e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MCLC PF05934.11 OAP56764.1 - 0.74 8.5 1.9 1.5 7.5 1.9 1.4 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) Gcn1_N PF12074.8 OAP56765.1 - 1.8e-87 293.9 2.4 1.8e-87 293.9 2.4 4.0 4 0 0 4 4 4 1 Generalcontrol nonderepressible 1 (Gcn1) N-terminal HEAT PF02985.22 OAP56765.1 - 5.9e-27 91.4 43.3 0.028 14.6 0.0 23.5 25 0 0 25 25 24 5 HEAT repeat HEAT_2 PF13646.6 OAP56765.1 - 1e-26 93.2 62.9 2.5e-07 31.0 1.5 16.8 11 6 8 19 19 19 6 HEAT repeats HEAT_EZ PF13513.6 OAP56765.1 - 5.8e-24 84.2 46.5 1.7e-07 31.6 0.0 18.7 18 3 4 22 22 19 6 HEAT-like repeat Cnd1 PF12717.7 OAP56765.1 - 1.6e-14 54.3 5.8 0.0081 16.2 0.1 9.9 9 2 1 10 10 10 2 non-SMC mitotic condensation complex subunit 1 ParcG PF10274.9 OAP56765.1 - 2.2e-12 47.5 1.1 0.00021 21.5 0.0 6.7 5 2 1 6 6 6 2 Parkin co-regulated protein CLASP_N PF12348.8 OAP56765.1 - 1.2e-11 44.6 0.0 0.35 10.4 0.0 7.2 5 1 2 8 8 8 3 CLASP N terminal Vac14_Fab1_bd PF12755.7 OAP56765.1 - 5.6e-11 42.9 0.0 1.6 9.3 0.0 8.6 7 3 1 9 9 9 3 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 OAP56765.1 - 1.4e-06 27.2 5.8 0.49 8.9 0.3 7.0 5 2 2 7 7 7 2 Adaptin N terminal region UME PF08064.13 OAP56765.1 - 1.7e-05 24.6 10.1 1.2 9.0 0.0 9.4 10 2 2 12 12 9 1 UME (NUC010) domain Cohesin_HEAT PF12765.7 OAP56765.1 - 0.00048 20.4 14.0 1.9 8.9 0.1 6.8 7 0 0 7 7 7 3 HEAT repeat associated with sister chromatid cohesion Ipi1_N PF12333.8 OAP56765.1 - 0.0015 19.1 1.4 0.31 11.6 0.1 5.0 5 1 0 5 5 5 1 Rix1 complex component involved in 60S ribosome maturation TIP120 PF08623.10 OAP56765.1 - 0.014 15.2 0.1 1.1 9.0 0.0 4.1 4 1 1 5 5 5 0 TATA-binding protein interacting (TIP20) MMS19_C PF12460.8 OAP56765.1 - 0.03 13.5 17.4 0.81 8.7 0.9 7.0 7 2 0 8 8 8 0 RNAPII transcription regulator C-terminal Vitellogenin_N PF01347.22 OAP56765.1 - 0.067 11.6 0.1 0.56 8.5 0.0 2.4 3 0 0 3 3 3 0 Lipoprotein amino terminal region Tti2 PF10521.9 OAP56765.1 - 0.074 12.6 0.2 7.7 6.0 0.0 4.1 4 0 0 4 4 4 0 Tti2 family TFCD_C PF12612.8 OAP56765.1 - 0.1 12.4 0.0 0.1 12.4 0.0 4.0 4 1 1 5 5 4 0 Tubulin folding cofactor D C terminal Aconitase_B_N PF11791.8 OAP56765.1 - 0.16 12.0 0.6 5 7.2 0.0 4.0 4 0 0 4 4 4 0 Aconitate B N-terminal domain Arm PF00514.23 OAP56765.1 - 1.1 9.4 11.3 65 3.8 0.1 7.8 9 0 0 9 9 9 0 Armadillo/beta-catenin-like repeat Peptidase_M41 PF01434.18 OAP56766.1 - 6.5e-66 221.8 0.0 1.4e-65 220.7 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 OAP56766.1 - 2.6e-43 147.6 0.0 8.4e-43 146.0 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OAP56766.1 - 1.9e-12 46.8 0.1 5.2e-12 45.4 0.1 1.8 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 OAP56766.1 - 3.7e-07 30.5 0.0 9.1e-07 29.2 0.0 1.7 1 0 0 1 1 1 1 FtsH Extracellular AAA_5 PF07728.14 OAP56766.1 - 0.0005 20.1 0.0 0.0018 18.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OAP56766.1 - 0.0024 18.3 0.3 0.16 12.3 0.2 2.9 1 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 OAP56766.1 - 0.0025 17.6 0.0 0.037 13.8 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Phage_Gp15 PF06854.11 OAP56766.1 - 0.0036 17.3 0.1 0.0073 16.3 0.1 1.4 1 0 0 1 1 1 1 Bacteriophage Gp15 protein TIP49 PF06068.13 OAP56766.1 - 0.011 15.0 0.0 0.019 14.2 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_22 PF13401.6 OAP56766.1 - 0.035 14.4 2.3 1.2 9.4 0.1 3.4 5 0 0 5 5 4 0 AAA domain AAA_2 PF07724.14 OAP56766.1 - 0.067 13.3 0.0 0.22 11.6 0.0 1.9 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) RNA_pol PF00940.19 OAP56766.1 - 0.14 10.9 0.0 0.23 10.3 0.0 1.2 1 0 0 1 1 1 0 DNA-dependent RNA polymerase IstB_IS21 PF01695.17 OAP56766.1 - 0.21 11.3 0.3 0.43 10.3 0.0 1.7 2 0 0 2 2 1 0 IstB-like ATP binding protein AAA_17 PF13207.6 OAP56766.1 - 0.31 11.4 1.9 0.38 11.2 0.0 2.2 3 0 0 3 3 1 0 AAA domain Pox_Ag35 PF03286.14 OAP56766.1 - 4 7.2 8.5 9.2 6.0 1.9 2.3 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Inhibitor_Mig-6 PF11555.8 OAP56767.1 - 0.4 10.8 7.0 0.21 11.7 0.8 3.0 2 0 0 2 2 2 0 EGFR receptor inhibitor Mig-6 LRR_4 PF12799.7 OAP56768.1 - 0.0039 17.6 2.1 0.84 10.1 0.1 4.2 2 1 2 4 4 4 2 Leucine Rich repeats (2 copies) Pkinase PF00069.25 OAP56769.1 - 3.8e-59 200.2 0.0 3.6e-58 197.0 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP56769.1 - 1.2e-28 100.2 0.1 1.5e-19 70.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 OAP56769.1 - 3.3e-05 23.9 5.5 0.21 11.5 0.1 3.7 2 1 2 4 4 4 3 Phosphotransferase enzyme family Pkinase_C PF00433.24 OAP56769.1 - 0.00033 21.3 1.0 0.0023 18.6 0.3 2.5 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.6 OAP56769.1 - 0.0014 18.0 0.1 0.0087 15.4 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 OAP56769.1 - 0.024 13.6 0.0 0.054 12.4 0.0 1.5 1 1 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 OAP56769.1 - 0.058 12.7 0.0 0.14 11.5 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MmgE_PrpD PF03972.14 OAP56770.1 - 2.9e-145 484.2 0.0 3.3e-145 484.0 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family Glyco_hydro_3_C PF01915.22 OAP56771.1 - 1.4e-44 152.5 0.0 5.7e-44 150.5 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 OAP56771.1 - 7.8e-41 140.5 0.0 1.2e-40 139.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 OAP56771.1 - 1.8e-21 76.0 0.1 3.5e-21 75.1 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain FMO-like PF00743.19 OAP56772.1 - 3.6e-15 55.4 0.1 5.9e-13 48.1 0.1 2.6 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OAP56772.1 - 2.3e-09 37.3 0.0 1.7e-08 34.6 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAP56772.1 - 3.7e-05 23.1 0.0 0.19 11.0 0.0 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAP56772.1 - 5.8e-05 22.8 0.0 0.00047 19.9 0.0 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 OAP56772.1 - 0.00015 21.0 2.0 0.00041 19.6 0.0 2.6 4 0 0 4 4 4 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 OAP56772.1 - 0.0022 17.3 0.1 0.48 9.6 0.0 3.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAC PF01849.18 OAP56774.1 - 4.5e-24 84.2 0.4 1.1e-23 83.0 0.4 1.7 1 0 0 1 1 1 1 NAC domain Abhydrolase_2 PF02230.16 OAP56775.1 - 1.3e-59 201.7 0.0 1.6e-59 201.4 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 OAP56775.1 - 2.5e-07 30.2 0.2 0.0014 18.0 0.0 3.1 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 OAP56775.1 - 1.1e-05 25.1 1.0 9.2e-05 22.0 0.0 2.3 3 0 0 3 3 3 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 OAP56775.1 - 0.00034 21.3 0.0 0.00055 20.6 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.13 OAP56775.1 - 0.00043 20.0 0.0 0.003 17.2 0.0 2.2 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.20 OAP56775.1 - 0.011 15.4 0.2 0.39 10.3 0.1 2.7 1 1 1 2 2 2 0 alpha/beta hydrolase fold DUF1581 PF07619.11 OAP56775.1 - 0.027 14.6 0.0 0.045 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1581) DLH PF01738.18 OAP56775.1 - 0.028 14.0 0.0 0.04 13.5 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 OAP56775.1 - 0.076 12.9 0.0 6.7 6.5 0.0 2.2 1 1 0 2 2 2 0 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 OAP56775.1 - 0.18 11.4 0.0 0.57 9.8 0.0 1.8 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region EutQ PF06249.12 OAP56776.1 - 5.8e-10 39.1 0.0 7.7e-10 38.7 0.0 1.1 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Cupin_3 PF05899.12 OAP56776.1 - 1.6e-09 37.3 0.0 2.3e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_2 PF07883.11 OAP56776.1 - 0.0001 21.9 0.1 0.00015 21.4 0.1 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 OAP56776.1 - 0.028 14.0 0.0 0.044 13.4 0.0 1.3 1 0 0 1 1 1 0 Cupin Fungal_trans_2 PF11951.8 OAP56777.1 - 4.3e-59 200.3 0.8 6.1e-59 199.8 0.8 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP56777.1 - 3.5e-06 27.0 13.4 5.6e-06 26.4 13.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Epimerase PF01370.21 OAP56778.1 - 3.1e-18 66.1 0.0 4.4e-18 65.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 OAP56778.1 - 3e-10 39.7 0.0 1.1e-09 37.8 0.0 1.8 2 0 0 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.19 OAP56778.1 - 2.3e-08 33.4 0.0 4.3e-08 32.5 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 OAP56778.1 - 9.9e-07 28.5 0.2 5.3e-06 26.0 0.2 1.9 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 OAP56778.1 - 0.039 13.4 0.2 4.6 6.6 0.0 2.3 2 0 0 2 2 2 0 short chain dehydrogenase NmrA PF05368.13 OAP56778.1 - 0.079 12.5 0.0 8.4 5.9 0.0 2.6 3 0 0 3 3 3 0 NmrA-like family KR PF08659.10 OAP56778.1 - 0.12 12.2 0.3 0.48 10.3 0.3 1.8 1 1 0 1 1 1 0 KR domain adh_short PF00106.25 OAP56779.1 - 4e-28 98.2 0.5 1.3e-26 93.3 0.5 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP56779.1 - 1.2e-12 47.9 0.1 2.8e-11 43.5 0.1 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP56779.1 - 7.6e-10 39.0 0.2 1.3e-09 38.2 0.2 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OAP56779.1 - 5e-05 22.6 0.1 0.00021 20.6 0.0 1.8 1 1 0 2 2 2 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 OAP56779.1 - 0.0013 18.2 0.0 0.0019 17.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 OAP56779.1 - 0.01 16.1 0.0 0.022 15.0 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 OAP56779.1 - 0.14 12.2 0.1 0.4 10.7 0.1 1.8 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Ctr PF04145.15 OAP56780.1 - 1.7e-30 106.6 0.1 2e-30 106.3 0.1 1.1 1 0 0 1 1 1 1 Ctr copper transporter family Pyridox_oxase_2 PF12766.7 OAP56781.1 - 2.3e-25 89.1 0.0 4.3e-25 88.2 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DAO PF01266.24 OAP56782.1 - 3e-38 132.3 0.0 3.5e-38 132.1 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 OAP56782.1 - 1.1e-08 35.2 0.1 0.0068 16.4 0.2 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 OAP56782.1 - 7e-07 29.4 0.0 1.5e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAP56782.1 - 4.6e-05 22.8 0.0 0.00081 18.7 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 OAP56782.1 - 5.2e-05 22.3 0.1 0.00062 18.7 0.1 2.1 1 1 0 1 1 1 1 Tryptophan halogenase GIDA PF01134.22 OAP56782.1 - 6.4e-05 22.2 0.1 0.00074 18.7 0.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 OAP56782.1 - 0.012 14.7 0.4 0.035 13.2 0.4 1.7 1 1 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 OAP56782.1 - 0.022 13.5 0.0 0.11 11.2 0.0 1.8 2 0 0 2 2 2 0 HI0933-like protein K_oxygenase PF13434.6 OAP56782.1 - 0.041 13.0 0.0 0.28 10.3 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 OAP56782.1 - 0.057 14.0 0.0 0.66 10.6 0.0 2.6 4 0 0 4 4 4 0 Pyridine nucleotide-disulphide oxidoreductase AMP-binding PF00501.28 OAP56783.1 - 6.2e-71 239.2 0.0 7.7e-71 238.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAP56783.1 - 0.00011 23.1 0.0 0.00022 22.1 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Ank_2 PF12796.7 OAP56784.1 - 3.6e-41 139.6 5.6 3.7e-17 62.7 0.1 4.3 1 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAP56784.1 - 8.3e-38 128.3 10.4 1.3e-08 35.2 0.0 7.9 1 1 7 8 8 8 8 Ankyrin repeats (many copies) Ank PF00023.30 OAP56784.1 - 6.5e-27 92.8 10.7 4e-05 23.9 0.0 7.8 7 0 0 7 7 7 7 Ankyrin repeat Ank_3 PF13606.6 OAP56784.1 - 9.6e-25 84.0 5.4 0.00089 19.5 0.0 9.1 9 0 0 9 9 9 7 Ankyrin repeat Ank_5 PF13857.6 OAP56784.1 - 5.1e-20 71.3 9.2 1e-05 25.7 0.0 6.2 1 1 7 8 8 8 7 Ankyrin repeats (many copies) HeLo PF14479.6 OAP56784.1 - 0.056 13.3 0.0 0.13 12.1 0.0 1.7 1 1 0 1 1 1 0 Prion-inhibition and propagation PTE PF02126.18 OAP56784.1 - 0.17 11.3 0.3 1.6 8.1 0.1 2.3 1 1 1 2 2 2 0 Phosphotriesterase family Y_phosphatase2 PF03162.13 OAP56786.1 - 6.9e-39 133.1 0.0 1.1e-38 132.4 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 OAP56786.1 - 1.8e-08 34.6 0.0 1.1e-07 32.0 0.0 2.0 2 1 0 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.20 OAP56786.1 - 0.00065 19.5 0.1 0.0013 18.6 0.0 1.6 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 OAP56786.1 - 0.066 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein-tyrosine phosphatase TatD_DNase PF01026.21 OAP56787.1 - 5.2e-50 170.2 0.0 6.6e-50 169.9 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase BRCA-2_OB1 PF09103.10 OAP56787.1 - 0.14 12.1 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 FMN_dh PF01070.18 OAP56788.1 - 3.4e-88 296.0 0.2 1.6e-87 293.8 0.2 1.8 1 1 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 OAP56788.1 - 4.6e-18 65.1 0.0 9.5e-18 64.1 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 OAP56788.1 - 9.3e-05 21.7 0.0 0.00014 21.1 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase PPR_2 PF13041.6 OAP56789.1 - 3.2e-10 40.0 0.9 0.043 14.0 0.0 4.9 4 1 1 5 5 5 4 PPR repeat family PPR PF01535.20 OAP56789.1 - 2.1e-05 24.4 0.2 0.053 13.8 0.0 4.0 4 0 0 4 4 4 2 PPR repeat PPR_3 PF13812.6 OAP56789.1 - 0.0011 19.0 0.2 0.32 11.1 0.0 3.1 3 0 0 3 3 3 1 Pentatricopeptide repeat domain PPR_long PF17177.4 OAP56789.1 - 0.0095 15.3 0.2 0.027 13.9 0.0 1.7 2 0 0 2 2 2 1 Pentacotripeptide-repeat region of PRORP Vps5 PF09325.10 OAP56789.1 - 0.07 12.7 3.0 0.13 11.8 0.2 2.2 2 0 0 2 2 2 0 Vps5 C terminal like MRP-S25 PF13741.6 OAP56790.1 - 2.5e-72 243.1 0.8 3.3e-72 242.8 0.8 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.9 OAP56790.1 - 0.0022 18.2 1.6 2.8 8.2 0.1 3.0 3 0 0 3 3 3 2 Mitochondrial ribosomal protein S23 Vfa1 PF08432.10 OAP56791.1 - 3.3e-56 190.5 13.5 3.7e-56 190.3 13.5 1.0 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 U79_P34 PF03064.16 OAP56791.1 - 0.014 14.7 10.9 0.016 14.6 10.9 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 PPL5 PF18168.1 OAP56791.1 - 0.015 14.6 6.4 0.018 14.4 6.4 1.1 1 0 0 1 1 1 0 Prim-pol family 5 DUF5093 PF17011.5 OAP56791.1 - 0.018 15.3 4.3 0.034 14.4 4.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5093) RXT2_N PF08595.11 OAP56791.1 - 0.022 14.8 6.5 0.03 14.4 6.5 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal Spt20 PF12090.8 OAP56791.1 - 0.11 12.0 6.6 0.25 10.9 6.6 1.4 1 1 0 1 1 1 0 Spt20 family LRIF1 PF15741.5 OAP56791.1 - 0.12 10.9 7.1 0.13 10.8 7.1 1.0 1 0 0 1 1 1 0 Ligand-dependent nuclear receptor-interacting factor 1 DUF913 PF06025.12 OAP56791.1 - 0.22 10.5 1.8 0.26 10.2 1.8 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Sporozoite_P67 PF05642.11 OAP56791.1 - 0.45 8.5 5.6 0.5 8.4 5.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Sec16 PF12932.7 OAP56791.1 - 0.46 11.1 5.6 0.53 10.9 4.9 1.6 1 1 0 1 1 1 0 Vesicle coat trafficking protein Sec16 mid-region Connexin PF00029.19 OAP56791.1 - 0.87 9.3 4.2 1.1 9.0 4.2 1.2 1 0 0 1 1 1 0 Connexin CDC45 PF02724.14 OAP56791.1 - 1.7 6.9 11.0 1.9 6.7 11.0 1.1 1 0 0 1 1 1 0 CDC45-like protein TP53IP5 PF15331.6 OAP56791.1 - 1.8 8.7 10.6 2.4 8.2 10.6 1.1 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 DASH_Spc19 PF08287.11 OAP56791.1 - 1.9 8.4 10.1 2.6 7.9 10.1 1.2 1 0 0 1 1 1 0 Spc19 DUF4820 PF16091.5 OAP56791.1 - 3.1 7.1 8.9 0.15 11.4 3.4 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) RR_TM4-6 PF06459.12 OAP56791.1 - 5.5 6.7 17.7 9.4 6.0 17.7 1.4 1 1 0 1 1 1 0 Ryanodine Receptor TM 4-6 NPR3 PF03666.13 OAP56791.1 - 6.1 5.5 9.8 6.9 5.3 9.8 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 RRN3 PF05327.11 OAP56791.1 - 9.3 4.6 9.5 10 4.5 9.5 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DSPc PF00782.20 OAP56792.1 - 9.2e-20 70.8 0.0 5.5e-08 32.7 0.1 3.2 3 0 0 3 3 3 3 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 OAP56792.1 - 0.034 13.7 0.0 0.051 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase zf-C2H2 PF00096.26 OAP56793.1 - 0.0004 20.7 20.7 0.014 15.9 1.7 4.7 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OAP56793.1 - 0.067 13.7 0.3 0.067 13.7 0.3 3.2 3 0 0 3 3 3 0 Zinc-finger double domain zf-CHCC PF10276.9 OAP56793.1 - 0.19 11.8 4.0 8.7 6.5 0.2 2.4 2 0 0 2 2 2 0 Zinc-finger domain zf-FCS PF06467.14 OAP56793.1 - 0.21 11.5 3.2 8.8 6.4 0.4 2.7 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zf-C2H2_4 PF13894.6 OAP56793.1 - 0.3 12.0 20.3 0.48 11.4 1.8 4.6 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OAP56793.1 - 2.4 8.5 14.0 0.15 12.4 3.9 3.3 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Med14 PF08638.11 OAP56795.1 - 0.022 14.2 0.0 0.024 14.1 0.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit MED14 PWI PF01480.17 OAP56797.1 - 8.1e-32 109.4 0.0 2.1e-31 108.0 0.0 1.8 1 0 0 1 1 1 1 PWI domain LETM1 PF07766.13 OAP56798.1 - 1.7e-105 352.2 0.4 1.7e-105 352.2 0.4 2.3 2 0 0 2 2 2 1 LETM1-like protein SAP PF02037.27 OAP56798.1 - 4.9e-05 23.0 1.0 0.0029 17.3 0.0 3.7 4 0 0 4 4 4 1 SAP domain Neur_chan_memb PF02932.16 OAP56798.1 - 9.1 6.3 11.1 5.6 7.0 3.3 2.3 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region SMC_N PF02463.19 OAP56799.1 - 1.4e-55 188.1 0.0 3.7e-30 105.0 0.0 3.2 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 OAP56799.1 - 5.4e-31 107.3 0.0 2.6e-30 105.1 0.0 2.3 2 0 0 2 2 1 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 OAP56799.1 - 2.3e-13 51.1 20.8 7.7e-12 46.1 12.2 6.1 3 2 1 5 5 2 2 AAA domain AAA_21 PF13304.6 OAP56799.1 - 2.7e-12 47.1 9.1 1.2e-06 28.5 0.0 4.5 4 1 1 5 5 5 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 OAP56799.1 - 6.2e-11 42.6 2.2 6.2e-11 42.6 2.2 4.2 2 2 0 3 3 2 1 AAA ATPase domain AAA_29 PF13555.6 OAP56799.1 - 4.8e-09 35.8 0.0 1e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Spc7 PF08317.11 OAP56799.1 - 5.4e-05 22.2 15.3 5.4e-05 22.2 15.3 6.2 3 2 2 6 6 6 4 Spc7 kinetochore protein SbcCD_C PF13558.6 OAP56799.1 - 0.0022 18.2 0.0 0.013 15.7 0.0 2.4 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.14 OAP56799.1 - 0.39 10.7 2.5 22 5.1 1.8 3.2 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 OAP56799.1 - 0.98 9.9 0.0 0.98 9.9 0.0 6.0 4 2 0 4 4 3 0 ABC transporter Laminin_II PF06009.12 OAP56799.1 - 5.3 7.1 51.1 0.099 12.7 1.8 6.9 4 1 1 6 6 6 0 Laminin Domain II DUF1664 PF07889.12 OAP56799.1 - 7.6 6.6 48.6 0.099 12.7 2.0 7.9 4 3 4 8 8 8 0 Protein of unknown function (DUF1664) DUF2838 PF10998.8 OAP56800.1 - 9.2e-43 145.0 10.8 9.2e-43 145.0 10.8 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2838) Curto_V3 PF07436.11 OAP56800.1 - 0.11 12.9 0.1 0.31 11.5 0.1 1.7 1 0 0 1 1 1 0 Curtovirus V3 protein OmpH PF03938.14 OAP56800.1 - 0.13 12.6 2.5 0.18 12.2 0.6 1.8 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Glyco_hydro_cc PF11790.8 OAP56802.1 - 1.2e-47 162.5 0.1 1.5e-47 162.2 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Hydrolase_6 PF13344.6 OAP56803.1 - 3.8e-30 104.0 0.0 6.3e-30 103.3 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OAP56803.1 - 8.6e-15 54.6 0.0 2e-14 53.4 0.0 1.6 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 OAP56803.1 - 5e-10 40.0 0.0 3.6e-08 34.0 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 OAP56803.1 - 2.9e-05 24.2 0.0 0.025 14.7 0.0 2.2 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase PNK3P PF08645.11 OAP56803.1 - 0.063 13.0 0.0 2.5 7.8 0.0 2.3 2 0 0 2 2 2 0 Polynucleotide kinase 3 phosphatase Peptidase_M18 PF02127.15 OAP56804.1 - 3.9e-165 549.8 0.0 6.8e-165 549.0 0.0 1.4 1 1 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Toprim_2 PF13155.6 OAP56804.1 - 0.091 13.2 0.0 0.2 12.1 0.0 1.5 1 0 0 1 1 1 0 Toprim-like WD40 PF00400.32 OAP56805.1 - 3.6e-23 81.4 13.4 0.00016 22.4 0.1 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAP56805.1 - 7.3e-14 51.8 3.8 1.3e-05 25.4 0.1 4.1 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OAP56805.1 - 4.9e-06 26.5 0.1 0.084 12.7 0.0 3.1 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 OAP56805.1 - 0.0075 15.3 0.0 0.03 13.3 0.0 1.9 2 0 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PALB2_WD40 PF16756.5 OAP56805.1 - 0.18 10.7 1.0 13 4.6 0.1 2.3 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain Biotin_lipoyl PF00364.22 OAP56806.1 - 3.2e-20 71.7 1.0 5.9e-20 70.9 1.0 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 OAP56806.1 - 5.8e-09 36.1 0.1 2.1e-08 34.4 0.1 2.0 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 OAP56806.1 - 5.6e-05 22.9 0.0 0.0018 18.1 0.0 2.7 2 1 0 2 2 2 1 Biotin-lipoyl like HlyD_3 PF13437.6 OAP56806.1 - 0.062 14.0 0.1 1.6 9.4 0.0 2.6 1 1 1 2 2 2 0 HlyD family secretion protein ADH_zinc_N PF00107.26 OAP56807.1 - 2.4e-08 34.0 0.2 4.4e-08 33.2 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAP56807.1 - 3e-05 23.9 0.0 5.5e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Tcp11 PF05794.13 OAP56808.1 - 1.3e-92 311.2 6.1 1.6e-92 310.9 6.1 1.1 1 0 0 1 1 1 1 T-complex protein 11 Nbs1_C PF08599.10 OAP56808.1 - 5.9 7.1 7.3 1.3 9.2 2.8 2.2 2 0 0 2 2 2 0 DNA damage repair protein Nbs1 ILVD_EDD PF00920.21 OAP56809.1 - 2.2e-155 518.2 0.0 2.7e-155 517.9 0.0 1.1 1 0 0 1 1 1 1 Dehydratase family Spermine_synth PF01564.17 OAP56810.1 - 3.9e-06 26.4 0.0 6.2e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Methyltransf_30 PF05430.11 OAP56810.1 - 0.063 13.2 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase DUF2788 PF10981.8 OAP56810.1 - 0.12 12.4 0.1 0.29 11.2 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2788) RFX_DNA_binding PF02257.15 OAP56811.1 - 1.4e-27 96.1 0.1 3.1e-27 95.0 0.1 1.6 1 0 0 1 1 1 1 RFX DNA-binding domain Herpes_ori_bp PF02399.15 OAP56811.1 - 0.034 12.2 0.0 0.058 11.4 0.0 1.3 1 0 0 1 1 1 0 Origin of replication binding protein TB2_DP1_HVA22 PF03134.19 OAP56812.1 - 9.1e-27 92.8 9.2 9.1e-27 92.8 9.2 1.5 2 0 0 2 2 2 1 TB2/DP1, HVA22 family Peroxin-3 PF04882.12 OAP56813.1 - 1.5e-153 512.2 0.0 1.8e-153 512.0 0.0 1.1 1 0 0 1 1 1 1 Peroxin-3 Glycos_transf_2 PF00535.26 OAP56814.1 - 1.5e-21 76.9 0.1 1.9e-19 70.1 0.1 3.0 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 OAP56814.1 - 0.00068 19.6 0.0 0.1 12.5 0.0 2.4 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 OAP56814.1 - 0.13 11.7 0.0 4 6.8 0.0 2.1 2 0 0 2 2 2 0 Glycosyltransferase like family 2 SLC3A2_N PF16028.5 OAP56814.1 - 4 7.1 5.5 1.2 8.7 1.8 2.0 2 0 0 2 2 2 0 Solute carrier family 3 member 2 N-terminus NUDIX PF00293.28 OAP56815.1 - 3.1e-14 53.1 0.0 1.4e-13 51.0 0.0 1.8 2 0 0 2 2 2 1 NUDIX domain HET PF06985.11 OAP56816.1 - 2.6e-36 125.2 0.0 3.9e-36 124.6 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Pkinase PF00069.25 OAP56817.1 - 1.1e-23 83.9 0.0 7.5e-23 81.2 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP56817.1 - 5.8e-05 22.5 0.0 0.21 10.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 OAP56817.1 - 0.032 14.1 0.1 0.081 12.8 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Fungal_trans PF04082.18 OAP56818.1 - 1.2e-16 60.5 2.4 1.7e-16 60.1 2.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP56818.1 - 0.0005 20.1 11.6 0.00098 19.2 11.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 2OG-FeII_Oxy PF03171.20 OAP56819.1 - 6.9e-18 65.0 0.0 1.2e-17 64.3 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 OAP56819.1 - 6.6e-16 59.1 0.5 1.4e-15 58.1 0.5 1.6 1 1 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal AA_permease PF00324.21 OAP56820.1 - 2.7e-110 369.2 38.1 3.4e-110 368.9 38.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAP56820.1 - 2.9e-32 112.1 42.6 3.5e-32 111.8 42.6 1.0 1 0 0 1 1 1 1 Amino acid permease DIOX_N PF14226.6 OAP56821.1 - 4.1e-17 63.0 0.0 8.2e-17 62.1 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OAP56821.1 - 9.5e-17 61.3 0.0 1.6e-16 60.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily FAD_binding_3 PF01494.19 OAP56822.1 - 3.2e-71 240.4 0.1 3.9e-71 240.1 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAP56822.1 - 1.1e-08 35.0 1.2 3.6e-08 33.4 0.7 2.1 2 1 1 3 3 3 1 FAD dependent oxidoreductase Phe_hydrox_dim PF07976.12 OAP56822.1 - 3.2e-07 30.5 0.0 1.3e-05 25.3 0.0 2.4 1 1 1 2 2 2 1 Phenol hydroxylase, C-terminal dimerisation domain NAD_binding_8 PF13450.6 OAP56822.1 - 8.7e-06 25.9 0.3 3e-05 24.2 0.3 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAP56822.1 - 1.7e-05 24.3 0.5 9e-05 21.8 0.5 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAP56822.1 - 3.2e-05 23.3 0.1 5.7e-05 22.5 0.1 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 OAP56822.1 - 0.00016 21.0 0.0 0.00028 20.2 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAP56822.1 - 0.00018 20.8 0.7 0.00036 19.7 0.2 1.7 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 OAP56822.1 - 0.0002 20.2 0.7 0.013 14.2 0.2 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 OAP56822.1 - 0.00035 21.1 0.4 0.0096 16.5 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 OAP56822.1 - 0.00045 19.2 0.0 0.00076 18.4 0.0 1.4 1 0 0 1 1 1 1 Tryptophan halogenase FAD_oxidored PF12831.7 OAP56822.1 - 0.012 15.0 0.4 0.022 14.1 0.4 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 OAP56822.1 - 0.019 15.4 0.0 0.035 14.6 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding TrkA_N PF02254.18 OAP56822.1 - 0.033 14.5 0.0 0.074 13.3 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain GIDA PF01134.22 OAP56822.1 - 0.13 11.3 0.1 0.33 10.0 0.1 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A Sacchrp_dh_NADP PF03435.18 OAP56822.1 - 0.14 12.5 0.1 0.5 10.6 0.0 1.9 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain LRRNT PF01462.18 OAP56823.1 - 1.8 8.3 6.6 0.74 9.5 2.4 2.4 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain SKG6 PF08693.10 OAP56825.1 - 0.02 14.3 0.3 0.075 12.4 0.3 2.1 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Lysine_decarbox PF03641.14 OAP56826.1 - 3.1e-30 105.0 0.0 5.3e-30 104.2 0.0 1.4 1 1 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 OAP56826.1 - 6.7e-05 22.5 0.3 0.00077 19.1 0.3 2.1 1 1 0 1 1 1 1 SLOG cluster4 family DUF4169 PF13770.6 OAP56826.1 - 0.37 11.1 1.3 0.41 11.0 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4169) Proteasome PF00227.26 OAP56827.1 - 4.6e-50 169.8 0.1 5.7e-50 169.4 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 OAP56827.1 - 4.9e-12 45.3 0.3 4.9e-12 45.3 0.3 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature UPF0113 PF03657.13 OAP56827.1 - 0.072 13.4 0.1 20 5.5 0.0 2.8 3 0 0 3 3 3 0 UPF0113 PUA domain Vps55 PF04133.14 OAP56828.1 - 4.1e-41 139.6 9.6 4.6e-41 139.4 9.6 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 DUF4349 PF14257.6 OAP56828.1 - 0.95 8.9 4.6 0.18 11.2 0.7 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4349) UPF0220 PF05255.11 OAP56829.1 - 2.2e-73 245.3 5.7 2.5e-73 245.1 5.7 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) Fes1 PF08609.10 OAP56830.1 - 7.4e-30 103.7 0.7 5.7e-27 94.4 0.4 2.7 3 0 0 3 3 3 2 Nucleotide exchange factor Fes1 HEAT PF02985.22 OAP56830.1 - 5e-06 26.3 0.5 0.15 12.4 0.1 3.3 3 0 0 3 3 3 2 HEAT repeat HEAT_2 PF13646.6 OAP56830.1 - 6.6e-06 26.4 2.7 2.6e-05 24.5 1.2 2.5 2 2 0 2 2 2 1 HEAT repeats HEAT_EZ PF13513.6 OAP56830.1 - 3e-05 24.4 1.4 0.00013 22.4 1.4 2.2 1 0 0 1 1 1 1 HEAT-like repeat Arm PF00514.23 OAP56830.1 - 0.00052 20.0 0.8 0.15 12.1 0.1 3.1 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.20 OAP56830.1 - 0.12 10.9 0.2 6.7 5.1 0.0 1.8 1 1 1 2 2 2 0 Adaptin N terminal region Actin PF00022.19 OAP56831.1 - 2.6e-150 500.6 0.0 1e-149 498.6 0.0 1.7 1 1 0 1 1 1 1 Actin GHMP_kinases_N PF00288.26 OAP56832.1 - 1.5e-10 41.1 0.0 2.9e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 OAP56832.1 - 0.00056 20.2 0.0 0.0011 19.3 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal GARS_A PF01071.19 OAP56833.1 - 1.4e-82 276.2 0.1 1.3e-81 273.0 0.0 2.2 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain AIRS_C PF02769.22 OAP56833.1 - 6.7e-36 123.8 0.0 1.5e-35 122.7 0.0 1.6 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_N PF02844.15 OAP56833.1 - 6.1e-34 116.7 0.1 1.9e-33 115.1 0.1 1.9 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.16 OAP56833.1 - 1.2e-26 92.7 0.3 3.3e-26 91.4 0.3 1.8 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.24 OAP56833.1 - 1e-13 51.7 0.9 4.4e-13 49.7 0.9 2.1 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain ATP-grasp_3 PF02655.14 OAP56833.1 - 8.1e-05 22.7 0.1 0.00031 20.8 0.0 2.0 3 0 0 3 3 3 1 ATP-grasp domain ATP-grasp PF02222.22 OAP56833.1 - 0.00021 20.9 0.0 0.00037 20.1 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 OAP56833.1 - 0.003 17.2 0.0 0.025 14.2 0.0 2.1 2 0 0 2 2 2 1 RimK-like ATP-grasp domain ATPgrasp_ST PF14397.6 OAP56833.1 - 0.0056 16.0 0.0 0.07 12.4 0.0 2.2 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp ATP-grasp_4 PF13535.6 OAP56833.1 - 0.028 14.0 0.0 0.059 13.0 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain adh_short PF00106.25 OAP56834.1 - 9.4e-26 90.5 0.1 2.3e-25 89.2 0.1 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP56834.1 - 3e-16 59.7 0.2 4.3e-16 59.2 0.2 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 OAP56834.1 - 1.6e-09 37.6 0.1 2.1e-09 37.2 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 OAP56834.1 - 1e-08 35.3 0.4 1.3e-08 35.0 0.4 1.1 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 OAP56834.1 - 7.7e-05 22.7 0.2 0.00049 20.1 0.2 2.0 1 1 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 OAP56834.1 - 0.044 13.2 0.0 0.12 11.7 0.0 1.9 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase Fil_haemagg PF05594.14 OAP56834.1 - 0.22 12.1 2.6 0.56 10.8 2.6 1.6 1 0 0 1 1 1 0 Haemagluttinin repeat Pet127 PF08634.10 OAP56835.1 - 7.6e-114 379.8 0.2 1e-113 379.4 0.2 1.2 1 0 0 1 1 1 1 Mitochondrial protein Pet127 LRR_6 PF13516.6 OAP56836.1 - 0.023 14.7 5.3 25 5.3 0.1 5.6 6 0 0 6 6 6 0 Leucine Rich repeat Gly_transf_sug PF04488.15 OAP56837.1 - 2.2e-21 76.3 0.0 4.1e-21 75.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 OAP56837.1 - 2.1 7.6 2.9 1.1 8.5 0.3 1.6 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain Mid2 PF04478.12 OAP56838.1 - 0.0026 17.6 0.0 0.0063 16.4 0.0 1.6 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor NCU-G1 PF15065.6 OAP56838.1 - 0.1 11.6 0.8 0.2 10.6 0.7 1.5 1 1 0 1 1 1 0 Lysosomal transcription factor, NCU-G1 tRNA_deacylase PF04414.12 OAP56838.1 - 0.14 11.7 0.1 0.24 10.9 0.1 1.3 1 0 0 1 1 1 0 D-aminoacyl-tRNA deacylase Abhydrolase_1 PF00561.20 OAP56841.1 - 3.3e-10 40.1 0.0 1.9e-09 37.6 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAP56841.1 - 1.6e-09 37.4 0.0 3e-09 36.5 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Cohesin_load PF10345.9 OAP56842.1 - 4.4e-102 342.5 0.0 5.6e-102 342.1 0.0 1.0 1 0 0 1 1 1 1 Cohesin loading factor TPR_12 PF13424.6 OAP56842.1 - 0.00061 20.0 1.9 0.19 12.0 0.1 4.1 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 OAP56842.1 - 0.011 15.7 0.4 6.8 7.1 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 OAP56842.1 - 0.022 14.9 0.2 0.87 10.0 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 OAP56842.1 - 0.075 13.7 3.2 0.97 10.1 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 OAP56842.1 - 0.081 12.8 0.9 14 5.7 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 OAP56842.1 - 4.1 8.5 8.1 2.8 9.0 0.1 4.3 4 1 1 5 5 5 0 Tetratricopeptide repeat NIF PF03031.18 OAP56843.1 - 1.5e-20 73.5 0.0 2.3e-20 72.9 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF4407 PF14362.6 OAP56843.1 - 0.89 8.8 4.8 1.4 8.2 4.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RR_TM4-6 PF06459.12 OAP56843.1 - 1.6 8.5 4.3 2.9 7.6 4.3 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RRP36 PF06102.12 OAP56844.1 - 6.8e-39 133.5 27.2 6.8e-39 133.5 27.2 2.4 2 1 0 2 2 2 1 rRNA biogenesis protein RRP36 ADH_N PF08240.12 OAP56845.1 - 1.3e-18 66.9 2.1 2.3e-18 66.1 2.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAP56845.1 - 7.7e-12 45.3 0.1 1.8e-11 44.1 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 OAP56845.1 - 0.019 14.4 0.4 0.057 12.9 0.4 1.8 1 1 0 1 1 1 0 short chain dehydrogenase Amdase PF17645.1 OAP56845.1 - 0.021 14.4 0.0 3.5 7.2 0.0 2.4 2 0 0 2 2 2 0 Arylmalonate decarboxylase Methyltransf_25 PF13649.6 OAP56845.1 - 0.053 14.2 0.9 4.6 8.0 0.1 3.0 2 1 1 3 3 3 0 Methyltransferase domain T3SS_TC PF06511.11 OAP56845.1 - 0.13 11.6 0.2 0.21 11.0 0.2 1.2 1 0 0 1 1 1 0 Type III secretion systems tip complex components RNA_pol_L_2 PF13656.6 OAP56847.1 - 8.2e-30 102.4 0.0 1.1e-29 102.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 OAP56847.1 - 1.5e-10 40.4 0.0 2.9e-10 39.4 0.0 1.5 2 0 0 2 2 2 1 RNA polymerase Rpb3/Rpb11 dimerisation domain AdoMet_dc PF02675.15 OAP56847.1 - 0.0099 16.1 0.0 0.019 15.2 0.0 1.5 1 1 0 1 1 1 1 S-adenosylmethionine decarboxylase Nuc_deoxyri_tr3 PF11071.8 OAP56847.1 - 0.1 12.6 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 Nucleoside 2-deoxyribosyltransferase YtoQ Complex1_LYR_2 PF13233.6 OAP56848.1 - 3.6e-09 37.2 1.2 5.6e-09 36.6 1.2 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 OAP56848.1 - 7.6e-08 32.3 0.5 1.3e-07 31.5 0.5 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) IGPD PF00475.18 OAP56849.1 - 4.2e-56 189.2 0.2 2.8e-55 186.6 0.4 1.8 2 0 0 2 2 2 1 Imidazoleglycerol-phosphate dehydratase Arena_RNA_pol PF06317.11 OAP56849.1 - 0.069 10.3 0.0 0.091 9.9 0.0 1.0 1 0 0 1 1 1 0 Arenavirus RNA polymerase Histone PF00125.24 OAP56850.1 - 1.6e-42 145.0 0.4 2e-42 144.6 0.4 1.2 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 OAP56850.1 - 9.3e-06 25.7 0.1 1.4e-05 25.2 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 OAP56850.1 - 0.00034 21.0 0.1 0.00051 20.4 0.1 1.3 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 OAP56850.1 - 0.098 13.0 0.3 0.18 12.1 0.3 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DER1 PF04511.15 OAP56851.1 - 7.8e-52 176.0 3.7 9e-52 175.8 3.7 1.0 1 0 0 1 1 1 1 Der1-like family EF1G PF00647.19 OAP56852.1 - 2.4e-47 159.4 0.0 4.6e-47 158.5 0.0 1.5 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.25 OAP56852.1 - 3.8e-10 39.9 0.1 3.8e-10 39.9 0.1 2.5 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 OAP56852.1 - 4e-10 39.9 0.0 4e-10 39.9 0.0 2.7 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 OAP56852.1 - 3.1e-07 30.7 0.2 2.3e-06 27.9 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAP56852.1 - 2e-05 24.5 0.0 6e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 OAP56852.1 - 0.00048 20.4 0.1 0.0035 17.6 0.0 2.4 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 OAP56852.1 - 0.00065 19.8 0.0 0.0023 18.1 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Ribosomal_S9 PF00380.19 OAP56853.1 - 3.6e-41 140.5 0.1 5.6e-41 139.9 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S9/S16 TFIIA PF03153.13 OAP56854.1 - 1.7 8.5 8.2 1.9 8.4 8.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Clr5 PF14420.6 OAP56855.1 - 8.3e-12 45.1 1.2 8.3e-12 45.1 1.2 2.0 2 0 0 2 2 2 1 Clr5 domain TPR_2 PF07719.17 OAP56855.1 - 0.00021 21.2 0.0 3.5 8.0 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 OAP56855.1 - 0.0033 17.7 0.3 6 7.2 0.0 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat RskA PF10099.9 OAP56855.1 - 0.018 15.4 0.9 0.035 14.4 0.1 1.8 2 0 0 2 2 2 0 Anti-sigma-K factor rskA TPR_1 PF00515.28 OAP56855.1 - 0.049 13.5 0.0 19 5.3 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 OAP56855.1 - 0.05 13.8 0.0 14 6.2 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_MalT PF17874.1 OAP56855.1 - 0.058 12.7 2.6 0.066 12.6 1.2 1.8 2 0 0 2 2 2 0 MalT-like TPR region Erf4 PF10256.9 OAP56856.1 - 1.4e-37 128.4 0.0 2.2e-37 127.7 0.0 1.4 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family CFEM PF05730.11 OAP56857.1 - 3.5e-07 30.2 9.7 8.3e-07 29.0 9.7 1.7 1 0 0 1 1 1 1 CFEM domain Rep_fac_C PF08542.11 OAP56858.1 - 3.1e-23 82.0 0.0 8.5e-23 80.6 0.0 1.8 2 0 0 2 2 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 OAP56858.1 - 2.6e-13 50.1 0.0 7.8e-10 38.8 0.0 2.2 1 1 1 2 2 2 2 DNA polymerase III, delta subunit AAA PF00004.29 OAP56858.1 - 7.6e-11 42.6 0.0 1.3e-10 41.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 OAP56858.1 - 7.4e-07 29.3 0.0 1.3e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OAP56858.1 - 6.1e-06 26.7 0.0 0.00028 21.3 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 OAP56858.1 - 3e-05 23.8 0.0 6.7e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Viral_helicase1 PF01443.18 OAP56858.1 - 6.9e-05 22.7 0.0 0.00011 22.1 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_3 PF07726.11 OAP56858.1 - 8.6e-05 22.4 0.0 0.00015 21.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OAP56858.1 - 0.00021 21.6 0.1 0.38 11.0 0.1 2.4 1 1 1 2 2 2 2 AAA domain DNA_pol3_delta PF06144.13 OAP56858.1 - 0.00043 20.1 0.0 0.00067 19.5 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Mg_chelatase PF01078.21 OAP56858.1 - 0.0042 16.5 0.0 0.031 13.7 0.0 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI MeaB PF03308.16 OAP56858.1 - 0.0047 15.9 0.0 0.0085 15.1 0.0 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Rad17 PF03215.15 OAP56858.1 - 0.005 16.8 0.0 0.0092 15.9 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_assoc_2 PF16193.5 OAP56858.1 - 0.0063 16.8 0.0 0.028 14.7 0.0 2.1 2 0 0 2 2 2 1 AAA C-terminal domain AAA_24 PF13479.6 OAP56858.1 - 0.02 14.7 0.0 0.066 12.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 OAP56858.1 - 0.023 14.1 0.0 4.8 6.5 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein NTPase_1 PF03266.15 OAP56858.1 - 0.025 14.5 0.3 0.071 13.0 0.2 1.8 1 1 1 2 2 2 0 NTPase AAA_19 PF13245.6 OAP56858.1 - 0.029 14.7 0.1 0.074 13.4 0.1 1.8 1 1 0 1 1 1 0 AAA domain KTI12 PF08433.10 OAP56858.1 - 0.031 13.7 0.0 0.055 12.9 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_11 PF13086.6 OAP56858.1 - 0.051 13.4 0.0 0.077 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 OAP56858.1 - 0.14 11.7 0.1 0.74 9.4 0.1 2.0 1 1 1 2 2 2 0 AAA domain AAA_30 PF13604.6 OAP56858.1 - 0.16 11.7 0.1 0.54 10.0 0.1 1.8 1 1 0 1 1 1 0 AAA domain DEAD PF00270.29 OAP56858.1 - 0.17 11.6 0.1 2.2 8.0 0.0 2.2 1 1 1 2 2 2 0 DEAD/DEAH box helicase HET PF06985.11 OAP56859.1 - 2.1e-36 125.5 0.2 3.5e-36 124.7 0.2 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) NmrA PF05368.13 OAP56860.1 - 1.2e-18 67.5 0.0 1.7e-18 67.0 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAP56860.1 - 2e-17 63.7 0.0 3.2e-17 63.0 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAP56860.1 - 0.00047 19.7 0.0 0.0024 17.4 0.0 2.1 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OAP56860.1 - 0.0017 17.4 0.0 0.011 14.7 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Sacchrp_dh_NADP PF03435.18 OAP56860.1 - 0.04 14.2 0.0 0.12 12.7 0.0 1.7 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain KR PF08659.10 OAP56860.1 - 0.049 13.5 0.0 0.33 10.9 0.0 2.2 2 0 0 2 2 2 0 KR domain HTH_33 PF13592.6 OAP56860.1 - 0.076 12.7 0.1 2.7 7.7 0.1 2.4 2 0 0 2 2 2 0 Winged helix-turn helix TrkA_N PF02254.18 OAP56860.1 - 0.16 12.2 0.0 0.98 9.7 0.0 2.2 1 1 1 2 2 2 0 TrkA-N domain DUF4702 PF15774.5 OAP56860.1 - 0.17 10.8 0.0 0.25 10.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4702) DUF4464 PF14713.6 OAP56863.1 - 0.039 13.5 1.1 0.044 13.4 1.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4464) DUF3987 PF13148.6 OAP56863.1 - 0.052 12.6 3.4 0.061 12.3 3.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) NUDIX PF00293.28 OAP56865.1 - 3.2e-07 30.5 0.0 5e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain tRNA-synt_1e PF01406.19 OAP56866.1 - 3.7e-111 371.3 0.3 5.5e-111 370.7 0.3 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 OAP56866.1 - 1.4e-05 24.0 0.7 0.017 13.9 0.2 2.6 2 0 0 2 2 2 2 tRNA synthetases class I (M) DALR_2 PF09190.11 OAP56866.1 - 0.006 17.0 0.0 0.006 17.0 0.0 2.3 2 0 0 2 2 2 1 DALR domain tRNA-synt_1f PF01921.18 OAP56866.1 - 0.012 14.5 0.2 0.3 10.0 0.1 2.4 2 0 0 2 2 2 0 tRNA synthetases class I (K) DUF5388 PF17363.2 OAP56866.1 - 0.026 14.7 0.0 0.026 14.7 0.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5388) Arylsulfotran_2 PF14269.6 OAP56867.1 - 7.4e-57 193.0 0.9 1.3e-56 192.2 0.8 1.4 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 OAP56867.1 - 9.3e-19 67.6 0.0 3.2e-18 65.8 0.0 1.7 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Phage_holin_3_6 PF07332.11 OAP56867.1 - 2.3 8.3 4.7 4.4 7.4 0.0 2.2 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III RTA1 PF04479.13 OAP56868.1 - 1e-55 188.6 12.1 1e-55 188.6 12.1 1.9 1 1 1 2 2 2 2 RTA1 like protein GCD14 PF08704.10 OAP56869.1 - 1.2e-59 202.0 8.5 4.2e-37 128.1 0.5 3.5 3 1 0 3 3 3 2 tRNA methyltransferase complex GCD14 subunit Abhydrolase_4 PF08386.10 OAP56870.1 - 5.8e-18 64.9 0.0 1.1e-17 64.0 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.20 OAP56870.1 - 2.9e-17 63.1 0.5 1.6e-07 31.3 0.1 3.4 3 1 0 3 3 3 2 alpha/beta hydrolase fold Fungal_trans PF04082.18 OAP56871.1 - 6.2e-13 48.4 1.3 1e-12 47.7 1.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3669 PF12417.8 OAP56872.1 - 7.1e-19 67.8 0.0 1.9e-18 66.4 0.0 1.8 2 0 0 2 2 2 1 Zinc finger protein TMEM220 PF15071.6 OAP56872.1 - 0.12 13.2 0.1 0.39 11.5 0.0 1.8 2 0 0 2 2 2 0 Transmembrane family 220, helix Sugar_tr PF00083.24 OAP56873.1 - 6.9e-68 229.5 17.6 8.5e-68 229.3 17.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP56873.1 - 9.9e-17 60.9 19.4 9.9e-17 60.9 19.4 2.2 1 1 2 3 3 3 2 Major Facilitator Superfamily Glyco_hydro_127 PF07944.12 OAP56874.1 - 7.6e-119 397.5 0.0 9.2e-119 397.3 0.0 1.0 1 0 0 1 1 1 1 Beta-L-arabinofuranosidase, GH127 SH3_9 PF14604.6 OAP56874.1 - 0.099 12.5 0.0 1.5 8.8 0.0 2.6 2 0 0 2 2 2 0 Variant SH3 domain Glyco_hydro_39 PF01229.17 OAP56875.1 - 0.0065 15.1 0.2 0.0091 14.6 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 39 RraA-like PF03737.15 OAP56876.1 - 1e-35 123.1 0.0 1.2e-35 122.8 0.0 1.1 1 0 0 1 1 1 1 Aldolase/RraA adh_short PF00106.25 OAP56877.1 - 1.7e-14 53.7 0.1 5.4e-14 52.1 0.1 1.7 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP56877.1 - 1.4e-08 34.6 0.1 2e-08 34.1 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP56877.1 - 1.7e-06 28.1 0.1 2.5e-06 27.5 0.1 1.2 1 0 0 1 1 1 1 KR domain ABM PF03992.16 OAP56879.1 - 4e-11 42.9 0.0 0.00019 21.5 0.0 3.1 3 0 0 3 3 3 2 Antibiotic biosynthesis monooxygenase Glyco_tranf_2_3 PF13641.6 OAP56880.1 - 8.9e-18 65.0 0.0 1.4e-17 64.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 OAP56880.1 - 2.8e-14 53.3 0.0 5.1e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.6 OAP56880.1 - 7.9e-14 52.0 0.6 7.9e-14 52.0 0.6 3.2 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Cellulose_synt PF03552.14 OAP56880.1 - 1.1e-10 40.8 3.1 2.1e-07 29.9 2.5 2.5 1 1 2 3 3 3 2 Cellulose synthase Glyco_transf_21 PF13506.6 OAP56880.1 - 8e-10 38.5 0.0 1.3e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Chitin_synth_2 PF03142.15 OAP56880.1 - 0.027 13.1 3.9 0.058 12.0 0.2 2.7 2 1 1 3 3 3 0 Chitin synthase Glyco_hydro_12 PF01670.16 OAP56881.1 - 1.8e-16 60.8 3.6 1.4e-15 57.9 3.6 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 12 Ldi PF18566.1 OAP56882.1 - 3.8e-84 282.9 0.0 6.4e-84 282.2 0.0 1.4 1 0 0 1 1 1 1 Linalool dehydratase/isomerase Aldedh PF00171.22 OAP56883.1 - 1e-147 492.4 0.0 1.2e-147 492.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 OAP56883.1 - 0.099 11.7 0.0 0.22 10.6 0.0 1.8 1 1 0 1 1 1 0 Acyl-CoA reductase (LuxC) HEAT_2 PF13646.6 OAP56884.1 - 1.7e-08 34.7 8.7 0.24 11.8 0.0 7.5 6 2 2 8 8 8 3 HEAT repeats HEAT PF02985.22 OAP56884.1 - 3.1e-08 33.2 17.4 8.9 6.9 0.1 10.6 10 0 0 10 10 10 2 HEAT repeat HEAT_EZ PF13513.6 OAP56884.1 - 6.3e-05 23.4 7.5 21 5.7 0.0 8.2 7 0 0 7 7 7 1 HEAT-like repeat CLASP_N PF12348.8 OAP56884.1 - 0.00023 20.8 1.2 15 5.1 0.4 4.8 3 1 1 4 4 4 2 CLASP N terminal Vac14_Fab1_bd PF12755.7 OAP56884.1 - 0.02 15.4 0.0 0.19 12.3 0.0 2.9 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region Condensin2nSMC PF12422.8 OAP56884.1 - 0.17 12.1 0.3 12 6.1 0.0 3.7 4 0 0 4 4 4 0 Condensin II non structural maintenance of chromosomes subunit DUF89 PF01937.19 OAP56885.1 - 7.5e-132 439.6 0.0 8.5e-132 439.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 SPT_ssu-like PF11779.8 OAP56886.1 - 4.6e-24 83.8 5.3 7.3e-24 83.2 5.3 1.3 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like DUF1624 PF07786.12 OAP56886.1 - 0.015 14.8 0.3 0.018 14.6 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1624) Pet100 PF09803.9 OAP56887.1 - 6.6e-18 65.0 0.3 1.2e-17 64.2 0.1 1.4 1 1 0 1 1 1 1 Pet100 HemY_N PF07219.13 OAP56887.1 - 0.73 10.1 3.7 1 9.6 3.7 1.2 1 0 0 1 1 1 0 HemY protein N-terminus MFS_1 PF07690.16 OAP56888.1 - 2.5e-46 158.2 12.4 3.7e-46 157.7 12.4 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAP56888.1 - 1.9e-07 30.3 8.8 4.5e-07 29.1 8.7 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.20 OAP56888.1 - 0.084 11.1 0.1 0.28 9.4 0.1 1.7 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family F-box PF00646.33 OAP56889.1 - 0.00056 19.7 3.2 0.00067 19.5 0.4 2.5 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.7 OAP56889.1 - 0.013 15.4 0.3 0.03 14.2 0.3 1.6 1 0 0 1 1 1 0 F-box-like F-box-like_2 PF13013.6 OAP56889.1 - 0.034 14.1 0.1 0.084 12.9 0.1 1.7 1 1 0 1 1 1 0 F-box-like domain HTH_29 PF13551.6 OAP56889.1 - 0.11 12.6 0.1 0.55 10.3 0.0 2.1 2 0 0 2 2 2 0 Winged helix-turn helix TPR_10 PF13374.6 OAP56890.1 - 4.1e-42 140.9 3.9 4.5e-15 55.0 0.1 4.8 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_12 PF13424.6 OAP56890.1 - 1.6e-40 137.2 3.2 1.4e-15 57.3 0.4 3.9 2 1 2 4 4 3 3 Tetratricopeptide repeat TPR_7 PF13176.6 OAP56890.1 - 2.9e-12 45.7 2.1 0.034 14.2 0.0 4.9 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.28 OAP56890.1 - 4.6e-11 42.0 0.0 0.04 13.7 0.0 5.2 5 0 0 5 5 5 3 Tetratricopeptide repeat PNP_UDP_1 PF01048.20 OAP56890.1 - 6.5e-11 41.9 0.7 1.8e-10 40.5 0.7 1.7 1 1 0 1 1 1 1 Phosphorylase superfamily TPR_8 PF13181.6 OAP56890.1 - 1.9e-07 30.8 0.0 2.9 8.3 0.0 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat NB-ARC PF00931.22 OAP56890.1 - 2.2e-07 30.3 0.0 4.3e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain TPR_17 PF13431.6 OAP56890.1 - 5.1e-07 29.6 0.8 0.65 10.5 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat AAA_16 PF13191.6 OAP56890.1 - 3.8e-06 27.4 0.1 1.2e-05 25.7 0.0 2.0 2 0 0 2 2 1 1 AAA ATPase domain TPR_16 PF13432.6 OAP56890.1 - 4.2e-06 27.3 0.1 1.3 9.7 0.1 4.2 2 2 1 3 3 3 3 Tetratricopeptide repeat TPR_MalT PF17874.1 OAP56890.1 - 2e-05 24.1 0.7 4e-05 23.1 0.7 1.5 1 0 0 1 1 1 1 MalT-like TPR region TPR_4 PF07721.14 OAP56890.1 - 0.00015 22.1 0.0 11 7.0 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 OAP56890.1 - 0.00042 20.2 0.3 49 4.4 0.0 5.0 4 0 0 4 4 4 0 Tetratricopeptide repeat HSNSD PF12062.8 OAP56890.1 - 0.013 14.2 0.1 0.026 13.2 0.1 1.4 1 0 0 1 1 1 0 heparan sulfate-N-deacetylase TPR_14 PF13428.6 OAP56890.1 - 0.02 15.7 6.2 36 5.6 0.0 4.9 5 0 0 5 5 4 0 Tetratricopeptide repeat RPN2_C PF18004.1 OAP56890.1 - 1.1 9.1 3.4 20 5.1 0.2 3.0 2 1 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain TPR_10 PF13374.6 OAP56891.1 - 1.5e-95 310.9 16.0 6e-14 51.4 0.0 8.3 7 1 1 8 8 8 7 Tetratricopeptide repeat TPR_12 PF13424.6 OAP56891.1 - 5.6e-81 266.9 15.6 1.4e-19 70.2 0.1 5.2 2 1 3 5 5 5 5 Tetratricopeptide repeat TPR_1 PF00515.28 OAP56891.1 - 1.6e-32 110.0 4.3 0.0015 18.2 0.0 7.5 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_7 PF13176.6 OAP56891.1 - 1e-28 97.2 9.5 0.0031 17.4 0.0 7.6 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_8 PF13181.6 OAP56891.1 - 6.1e-25 85.3 2.4 0.026 14.7 0.0 7.5 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_17 PF13431.6 OAP56891.1 - 5.2e-19 67.2 11.0 0.041 14.3 0.1 7.6 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_4 PF07721.14 OAP56891.1 - 3.4e-17 61.3 5.6 0.61 10.9 0.1 7.7 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.17 OAP56891.1 - 3e-16 58.1 10.0 0.067 13.3 0.0 7.5 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.6 OAP56891.1 - 2.9e-14 53.4 6.0 0.00059 20.4 0.2 6.9 4 2 3 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.6 OAP56891.1 - 9.5e-13 47.8 10.8 1.1 10.3 0.0 7.5 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_MalT PF17874.1 OAP56891.1 - 1.3e-11 44.5 11.5 6.1e-09 35.7 3.3 3.2 1 1 1 3 3 3 2 MalT-like TPR region ANAPC3 PF12895.7 OAP56891.1 - 1.2e-09 38.2 1.2 0.0093 16.2 0.2 5.8 2 1 3 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.20 OAP56891.1 - 7e-09 35.3 1.1 29 5.2 0.0 7.5 8 0 0 8 8 7 0 PPR repeat TPR_19 PF14559.6 OAP56891.1 - 3.2e-07 30.8 9.7 0.083 13.4 0.2 5.5 2 1 5 7 7 7 4 Tetratricopeptide repeat DUF4919 PF16266.5 OAP56891.1 - 1.3e-05 25.2 1.4 0.25 11.3 0.0 3.7 1 1 3 4 4 4 2 Domain of unknown function (DUF4919) BTAD PF03704.17 OAP56891.1 - 1.9e-05 25.1 10.5 1 9.8 0.2 5.2 2 1 4 6 6 6 2 Bacterial transcriptional activator domain TPR_3 PF07720.12 OAP56891.1 - 0.0025 17.8 17.8 13 5.9 0.1 6.9 7 0 0 7 7 7 0 Tetratricopeptide repeat DUF5112 PF17139.4 OAP56891.1 - 0.0056 16.2 7.0 29 4.0 0.0 5.5 2 1 4 6 6 6 0 Domain of unknown function (DUF5112) DUF1925 PF09094.11 OAP56891.1 - 0.0068 16.7 7.5 46 4.4 0.0 5.4 2 1 3 5 5 5 0 Domain of unknown function (DUF1925) TPR_11 PF13414.6 OAP56891.1 - 0.0085 15.8 12.9 20 4.9 0.0 6.7 7 0 0 7 7 7 0 TPR repeat Topoisom_I PF01028.20 OAP56891.1 - 0.029 13.6 1.9 13 4.9 0.0 4.7 3 1 3 6 6 6 0 Eukaryotic DNA topoisomerase I, catalytic core Lipoprotein_3 PF00938.17 OAP56891.1 - 0.036 14.2 0.1 0.18 12.0 0.0 2.2 2 0 0 2 2 1 0 Lipoprotein ISG65-75 PF11727.8 OAP56891.1 - 0.072 12.3 5.3 18 4.5 0.1 4.5 2 1 3 5 5 5 0 Invariant surface glycoprotein TGT PF01702.18 OAP56891.1 - 0.1 11.7 0.2 0.19 10.9 0.1 1.5 1 1 0 1 1 1 0 Queuine tRNA-ribosyltransferase Mad3_BUB1_I PF08311.12 OAP56891.1 - 0.1 12.6 10.0 43 4.1 0.0 5.8 7 0 0 7 7 6 0 Mad3/BUB1 homology region 1 TetR_C_20 PF17925.1 OAP56891.1 - 0.17 12.2 6.4 34 4.8 0.0 5.2 3 1 3 7 7 6 0 Tetracyclin repressor-like, C-terminal domain DUF1152 PF06626.12 OAP56891.1 - 0.62 9.2 7.9 0.99 8.5 1.1 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF1152) RPN6_N PF18055.1 OAP56891.1 - 0.7 10.3 9.3 1.6 9.1 0.4 3.5 2 1 4 6 6 5 0 26S proteasome regulatory subunit RPN6 N-terminal domain Death PF00531.22 OAP56891.1 - 0.71 10.1 2.8 68 3.7 0.0 4.7 6 0 0 6 6 5 0 Death domain TPR_6 PF13174.6 OAP56891.1 - 1.8 9.4 7.5 29 5.6 0.0 4.6 5 0 0 5 5 3 0 Tetratricopeptide repeat MIT PF04212.18 OAP56891.1 - 6.3 7.0 19.5 7.6 6.7 0.1 6.0 4 2 2 6 6 6 0 MIT (microtubule interacting and transport) domain Exo_endo_phos PF03372.23 OAP56893.1 - 2.7e-06 27.1 0.0 5.4e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family WD40 PF00400.32 OAP56894.1 - 0.039 14.8 0.2 4.5 8.3 0.0 3.3 3 0 0 3 3 3 0 WD domain, G-beta repeat Nbas_N PF15492.6 OAP56894.1 - 0.1 11.9 0.0 0.24 10.7 0.0 1.6 1 1 0 1 1 1 0 Neuroblastoma-amplified sequence, N terminal CAF1 PF04857.20 OAP56895.1 - 4.8e-22 78.5 0.0 9.7e-11 41.4 0.0 2.1 2 0 0 2 2 2 2 CAF1 family ribonuclease NDUF_B12 PF08122.12 OAP56896.1 - 1.7e-24 85.6 1.8 2.7e-24 85.0 1.8 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family Cu_amine_oxid PF01179.20 OAP56897.1 - 8.4e-161 535.5 0.2 1e-160 535.2 0.2 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 OAP56897.1 - 8.4e-23 80.7 0.2 8.5e-22 77.5 0.1 2.3 2 0 0 2 2 2 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 OAP56897.1 - 7.1e-08 32.6 0.0 1.3e-07 31.8 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain RdgC PF04381.12 OAP56897.1 - 0.13 11.5 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 Putative exonuclease, RdgC Flavodoxin_1 PF00258.25 OAP56898.1 - 2.1e-32 112.3 0.0 4.2e-32 111.3 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin FAD_binding_1 PF00667.20 OAP56898.1 - 2.2e-31 109.1 0.0 3.1e-31 108.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 OAP56898.1 - 3.3e-14 53.4 0.0 5.6e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 OAP56898.1 - 0.096 12.9 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 Flavodoxin domain Collagen PF01391.18 OAP56899.1 - 0.0013 18.5 25.6 0.0013 18.5 25.6 3.0 2 1 0 2 2 2 1 Collagen triple helix repeat (20 copies) Ribosomal_S15 PF00312.22 OAP56899.1 - 0.0069 16.6 0.3 0.012 15.7 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein S15 Fib_alpha PF08702.10 OAP56899.1 - 0.22 11.7 2.2 0.33 11.1 2.2 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family ESM4 PF15952.5 OAP56899.1 - 0.33 11.3 4.6 0.45 10.9 4.6 1.4 1 1 0 1 1 1 0 Enhancer of split M4 family Pes-10 PF07149.11 OAP56899.1 - 1 8.3 5.3 1.5 7.8 5.3 1.1 1 0 0 1 1 1 0 Pes-10 Abhydrolase_6 PF12697.7 OAP56900.1 - 8e-05 23.3 0.1 0.00011 22.9 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAP56900.1 - 0.028 14.1 0.1 0.059 13.0 0.1 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold Zn_clus PF00172.18 OAP56901.1 - 1.7e-08 34.4 7.9 3.1e-08 33.6 7.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 OAP56901.1 - 1.7e-05 23.8 1.4 2.4e-05 23.3 1.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aminotran_5 PF00266.19 OAP56903.1 - 6.7e-29 101.0 0.0 2.4e-20 72.8 0.0 2.3 1 1 1 2 2 2 2 Aminotransferase class-V RNA_pol_3_Rpc31 PF11705.8 OAP56904.1 - 1.4e-35 123.6 65.5 9e-32 111.1 10.6 2.9 1 1 1 2 2 2 2 DNA-directed RNA polymerase III subunit Rpc31 TIMELESS_C PF05029.13 OAP56904.1 - 0.29 10.2 30.0 0.48 9.5 30.0 1.3 1 0 0 1 1 1 0 Timeless protein C terminal region AMP-binding PF00501.28 OAP56906.1 - 2.1e-79 267.1 0.0 2.6e-79 266.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAP56906.1 - 4.8e-17 62.7 0.8 1e-16 61.6 0.8 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain WSC PF01822.19 OAP56907.1 - 5.5e-07 29.7 13.3 1.2e-06 28.6 13.3 1.6 1 0 0 1 1 1 1 WSC domain Podoplanin PF05808.11 OAP56907.1 - 0.00056 20.0 1.7 0.00099 19.2 1.7 1.4 1 0 0 1 1 1 1 Podoplanin Rax2 PF12768.7 OAP56907.1 - 0.007 15.8 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 Cortical protein marker for cell polarity LapA_dom PF06305.11 OAP56907.1 - 0.074 12.9 0.2 0.074 12.9 0.2 1.6 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Mito_fiss_reg PF05308.11 OAP56907.1 - 9.9 6.2 7.7 18 5.3 7.7 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator FAD_binding_4 PF01565.23 OAP56910.1 - 2.6e-25 88.8 1.0 5.4e-25 87.7 1.0 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 OAP56910.1 - 0.0022 18.0 0.0 0.0053 16.8 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like Exo_endo_phos PF03372.23 OAP56911.1 - 7.2e-06 25.7 0.0 3e-05 23.6 0.0 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Fungal_trans PF04082.18 OAP56914.1 - 1.9e-15 56.6 1.2 8.4e-15 54.5 0.2 2.3 2 1 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 OAP56914.1 - 4.8e-11 42.5 7.7 4.9e-05 23.5 0.2 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAP56914.1 - 1.6e-08 34.7 7.5 0.0022 18.7 2.1 3.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OAP56914.1 - 3.4e-08 33.5 2.4 3.4e-08 33.5 2.4 3.5 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.8 OAP56914.1 - 0.00011 22.4 0.2 0.62 10.4 0.1 3.0 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 OAP56914.1 - 0.00043 20.5 3.7 0.00094 19.4 3.7 1.6 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 OAP56914.1 - 0.099 13.1 1.0 11 6.6 0.1 3.0 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.6 OAP56914.1 - 0.1 12.6 4.2 1.6 8.7 1.3 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf_C2H2_ZHX PF18387.1 OAP56914.1 - 3.9 7.2 6.0 0.68 9.6 0.6 2.5 2 1 1 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2HE PF16278.5 OAP56914.1 - 4.9 7.7 5.6 2.4 8.7 1.9 2.3 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger Lyase_1 PF00206.20 OAP56915.1 - 9.7e-114 380.0 0.0 1.5e-113 379.3 0.0 1.3 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 OAP56915.1 - 7.6e-21 74.3 0.0 1.9e-20 73.0 0.0 1.7 1 0 0 1 1 1 1 Fumarase C C-terminus Antimicrobial_2 PF08023.12 OAP56915.1 - 0.15 12.6 3.3 1.9 9.1 0.0 3.4 3 0 0 3 3 3 0 Frog antimicrobial peptide P4Ha_N PF08336.11 OAP56915.1 - 0.16 12.0 0.1 1.9 8.5 0.1 2.4 1 1 1 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Pyr_redox_2 PF07992.14 OAP56916.1 - 1.5e-26 93.3 0.0 2e-26 92.9 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAP56916.1 - 1.4e-08 35.2 4.1 6.2e-07 29.9 1.4 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAP56916.1 - 1.3e-07 31.2 1.1 2.2e-07 30.5 0.2 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAP56916.1 - 0.0051 16.8 3.4 7.9 6.4 0.1 3.7 3 1 1 4 4 4 2 FAD-NAD(P)-binding Trp_halogenase PF04820.14 OAP56916.1 - 0.028 13.3 3.2 1.1 8.0 0.1 2.3 2 0 0 2 2 2 0 Tryptophan halogenase Lycopene_cycl PF05834.12 OAP56916.1 - 0.1 11.6 4.1 2.5 7.0 0.0 2.9 2 1 1 3 3 3 0 Lycopene cyclase protein DUF3597 PF12200.8 OAP56917.1 - 0.18 12.3 1.9 0.25 11.9 1.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3597) SET PF00856.28 OAP56918.1 - 5.9e-09 36.5 0.0 9.9e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 SET domain Glu_cyclase_2 PF05096.12 OAP56918.1 - 0.032 13.7 0.0 0.046 13.1 0.0 1.1 1 0 0 1 1 1 0 Glutamine cyclotransferase TRI12 PF06609.13 OAP56919.1 - 5e-33 114.4 28.6 6.6e-33 114.0 28.6 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAP56919.1 - 1.8e-21 76.5 49.1 1.8e-21 76.5 49.1 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAP56919.1 - 1e-08 34.5 19.3 1e-08 34.5 19.3 3.2 1 1 2 3 3 3 2 Sugar (and other) transporter Ribosomal_S30 PF04758.14 OAP56921.1 - 3.2e-30 104.1 10.1 3.5e-30 104.0 10.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 UCH PF00443.29 OAP56922.1 - 1.2e-49 169.2 0.0 1.5e-49 168.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OAP56922.1 - 3.9e-11 43.1 6.0 2.5e-08 33.9 6.0 2.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 OAP56922.1 - 1.1e-07 31.4 0.1 3.1e-07 30.1 0.1 1.8 1 0 0 1 1 1 1 Ubiquitin family ARPC4 PF05856.12 OAP56923.1 - 1.5e-78 262.1 3.6 1.7e-78 262.0 3.6 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) Zn_clus PF00172.18 OAP56925.1 - 7.4e-08 32.4 7.6 1.1e-07 31.8 7.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2461 PF09365.10 OAP56926.1 - 8.3e-78 261.1 0.0 1.1e-77 260.7 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein (DUF2461) CDC45 PF02724.14 OAP56926.1 - 0.21 9.9 8.6 0.32 9.3 8.6 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 OAP56926.1 - 2 6.5 9.9 3.2 5.8 9.9 1.2 1 0 0 1 1 1 0 Nop14-like family ORC6 PF05460.13 OAP56926.1 - 6.5 5.9 10.6 10 5.3 10.6 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Presenilin PF01080.17 OAP56926.1 - 7.9 5.1 6.5 12 4.5 6.5 1.2 1 0 0 1 1 1 0 Presenilin Methyltransf_23 PF13489.6 OAP56927.1 - 1.7e-13 50.7 0.0 3.5e-13 49.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAP56927.1 - 4.2e-11 43.4 0.0 5.6e-08 33.4 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAP56927.1 - 5.6e-11 42.4 0.0 5.8e-07 29.4 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 OAP56927.1 - 1.8e-10 41.3 0.0 6.4e-05 23.5 0.0 2.5 1 1 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 OAP56927.1 - 3.7e-09 37.2 0.0 1e-07 32.6 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAP56927.1 - 1.1e-07 31.5 0.0 0.0071 15.7 0.0 2.3 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family TPMT PF05724.11 OAP56927.1 - 0.0012 18.5 0.0 0.0028 17.4 0.0 1.6 2 0 0 2 2 2 1 Thiopurine S-methyltransferase (TPMT) Pox_MCEL PF03291.16 OAP56927.1 - 0.021 13.9 0.0 0.035 13.2 0.0 1.6 1 1 0 1 1 1 0 mRNA capping enzyme N6_N4_Mtase PF01555.18 OAP56927.1 - 0.065 12.9 0.0 0.086 12.5 0.0 1.3 1 0 0 1 1 1 0 DNA methylase RrnaAD PF00398.20 OAP56927.1 - 0.084 11.9 0.0 0.14 11.2 0.0 1.4 1 1 0 1 1 1 0 Ribosomal RNA adenine dimethylase MTS PF05175.14 OAP56927.1 - 0.16 11.5 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain TYW3 PF02676.14 OAP56928.1 - 2.8e-60 203.3 0.1 6e-60 202.2 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase TYW3 Herpes_pp85 PF04637.12 OAP56928.1 - 1.7 7.0 3.8 2.6 6.4 3.8 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) EBP50_C PF09007.11 OAP56928.1 - 2.1 9.3 8.7 0.46 11.5 2.8 2.2 2 0 0 2 2 2 0 EBP50, C-terminal HAD PF12710.7 OAP56929.1 - 7.1e-23 82.0 0.0 1.1e-22 81.4 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 OAP56929.1 - 0.0023 17.4 0.0 0.0086 15.5 0.0 1.8 1 1 0 1 1 1 1 Putative Phosphatase UMPH-1 PF05822.12 OAP56929.1 - 0.0027 17.2 0.0 0.005 16.4 0.0 1.5 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) Hydrolase PF00702.26 OAP56929.1 - 0.018 15.4 0.2 0.055 13.7 0.2 2.0 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Acyl-CoA_dh_1 PF00441.24 OAP56931.1 - 8.6e-42 142.9 0.3 1.4e-41 142.2 0.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 OAP56931.1 - 1.2e-30 106.4 0.0 2.7e-30 105.3 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 OAP56931.1 - 1.8e-27 95.4 0.2 3.3e-27 94.5 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 OAP56931.1 - 1.8e-14 54.1 0.0 3.7e-14 53.2 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 OAP56931.1 - 5.1e-05 23.1 0.4 0.0002 21.1 0.4 1.9 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Oxidored_FMN PF00724.20 OAP56931.1 - 0.18 11.1 0.1 0.27 10.5 0.1 1.2 1 0 0 1 1 1 0 NADH:flavin oxidoreductase / NADH oxidase family IMS PF00817.20 OAP56932.1 - 5.9e-39 133.4 0.0 1.1e-38 132.6 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family zf_UBZ PF18439.1 OAP56932.1 - 1.8e-14 53.0 2.0 3.5e-14 52.1 2.0 1.5 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger IMS_C PF11799.8 OAP56932.1 - 2.4e-13 50.8 0.0 4.8e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 OAP56932.1 - 0.024 15.0 0.0 0.049 14.0 0.0 1.6 1 0 0 1 1 1 0 IMS family HHH motif DUF2197 PF09963.9 OAP56932.1 - 0.18 12.1 0.0 0.42 10.9 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2197) SLATT_fungal PF18142.1 OAP56933.1 - 1.3e-31 109.0 1.4 1.6e-31 108.8 0.2 1.7 2 0 0 2 2 2 1 SMODS and SLOG-associating 2TM effector domain SLATT_1 PF18181.1 OAP56933.1 - 0.031 14.2 0.2 0.031 14.2 0.2 1.7 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 TMPIT PF07851.13 OAP56933.1 - 0.64 9.2 3.3 3.7 6.7 0.1 2.1 2 0 0 2 2 2 0 TMPIT-like protein Fungal_trans PF04082.18 OAP56934.1 - 5.9e-29 100.9 0.9 1.2e-28 99.9 0.9 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain AMP-binding PF00501.28 OAP56935.1 - 1.3e-72 244.8 0.0 3.2e-72 243.4 0.0 1.6 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAP56935.1 - 1.7e-13 51.4 0.3 1.5e-07 32.2 0.0 3.0 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain CCDC144C PF14915.6 OAP56936.1 - 0.065 12.3 7.7 0.12 11.5 7.7 1.3 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region Mt_ATP-synt_D PF05873.12 OAP56936.1 - 0.13 12.1 0.5 0.28 11.0 0.5 1.5 1 0 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) DUF4763 PF15960.5 OAP56936.1 - 0.51 9.6 7.6 1.3 8.3 7.2 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4763) Phage_GP20 PF06810.11 OAP56936.1 - 2.6 7.8 7.5 0.41 10.5 3.5 1.6 2 0 0 2 2 2 0 Phage minor structural protein GP20 T5orf172 PF10544.9 OAP56937.1 - 1.9e-22 79.7 1.3 1.1e-21 77.3 1.3 2.2 1 1 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 OAP56937.1 - 4.4e-21 75.4 0.1 9.1e-21 74.3 0.1 1.6 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 Glyco_transf_28 PF03033.20 OAP56938.1 - 5.5e-18 65.3 0.1 2.8e-17 63.0 0.1 2.1 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 OAP56938.1 - 5.9e-06 25.4 0.0 1e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 OAP56938.1 - 0.011 15.7 0.0 0.023 14.7 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain PhyH PF05721.13 OAP56939.1 - 1.9e-24 87.1 0.0 2.7e-24 86.6 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Striatin PF08232.12 OAP56940.1 - 0.00029 21.5 2.0 0.00029 21.5 2.0 2.1 2 0 0 2 2 2 1 Striatin family CALCOCO1 PF07888.11 OAP56940.1 - 0.011 14.6 0.3 0.016 14.1 0.3 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like BBP1_C PF15272.6 OAP56940.1 - 0.12 12.2 0.3 0.23 11.2 0.1 1.5 2 0 0 2 2 2 0 Spindle pole body component BBP1, C-terminal Pox_A_type_inc PF04508.12 OAP56940.1 - 2.6 8.1 4.8 0.29 11.1 0.3 1.8 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Fungal_trans_2 PF11951.8 OAP56941.1 - 2.1e-05 23.5 0.1 3.4e-05 22.9 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain p450 PF00067.22 OAP56942.1 - 4.2e-37 128.0 0.0 5.1e-37 127.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 GMC_oxred_N PF00732.19 OAP56943.1 - 4.8e-56 190.3 0.0 6.8e-56 189.8 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAP56943.1 - 3.8e-34 118.3 0.0 6.1e-34 117.6 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 OAP56943.1 - 4.4e-06 26.0 0.6 0.0016 17.6 0.7 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 OAP56943.1 - 0.00026 20.1 0.3 0.00042 19.5 0.3 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 OAP56943.1 - 0.00042 20.5 0.2 0.0016 18.6 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAP56943.1 - 0.0016 18.1 2.3 0.0054 16.3 2.3 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 OAP56943.1 - 0.0064 15.8 0.1 0.011 15.0 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 OAP56943.1 - 0.018 14.3 0.0 0.64 9.2 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAP56943.1 - 0.022 14.0 0.0 0.035 13.3 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OAP56943.1 - 0.16 11.0 0.7 0.46 9.5 0.2 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A HI0933_like PF03486.14 OAP56943.1 - 0.18 10.5 0.3 0.25 10.0 0.3 1.2 1 0 0 1 1 1 0 HI0933-like protein Trp_halogenase PF04820.14 OAP56943.1 - 0.21 10.4 0.1 0.36 9.6 0.1 1.3 1 0 0 1 1 1 0 Tryptophan halogenase HlyIII PF03006.20 OAP56944.1 - 9.2e-11 41.9 3.8 1.1e-10 41.7 3.8 1.1 1 0 0 1 1 1 1 Haemolysin-III related DJ-1_PfpI PF01965.24 OAP56945.1 - 2.6e-09 37.1 0.0 8.4e-09 35.4 0.0 1.8 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 OAP56945.1 - 0.0014 18.3 0.0 0.0026 17.5 0.0 1.4 1 1 0 1 1 1 1 ThiJ/PfpI family-like Fungal_trans PF04082.18 OAP56946.1 - 4.7e-23 81.6 0.0 7.8e-23 80.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aldedh PF00171.22 OAP56947.1 - 5.4e-179 595.5 0.2 6.1e-179 595.4 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family TAXi_C PF14541.6 OAP56947.1 - 0.038 13.8 0.2 4.4 7.1 0.1 2.9 2 1 1 3 3 3 0 Xylanase inhibitor C-terminal RRM_1 PF00076.22 OAP56949.1 - 9.4e-33 111.9 0.3 1.3e-16 60.1 0.0 3.5 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OAP56949.1 - 0.00073 19.6 0.0 0.095 12.8 0.0 2.6 2 1 0 2 2 2 1 RNA recognition motif RRM_5 PF13893.6 OAP56949.1 - 0.00097 18.7 0.0 0.52 9.9 0.0 3.0 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.15 OAP56949.1 - 0.0016 18.4 0.8 1 9.4 0.1 2.4 2 0 0 2 2 2 2 DbpA RNA binding domain PHM7_cyt PF14703.6 OAP56949.1 - 0.0046 17.2 0.1 7.1 6.8 0.0 3.3 2 2 1 3 3 3 1 Cytosolic domain of 10TM putative phosphate transporter DUF4783 PF16022.5 OAP56949.1 - 0.025 14.7 0.1 0.31 11.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4783) DUF4944 PF16302.5 OAP56949.1 - 0.057 13.5 0.5 17 5.5 0.1 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4944) Limkain-b1 PF11608.8 OAP56949.1 - 0.059 13.4 0.2 18 5.5 0.0 2.8 3 0 0 3 3 3 0 Limkain b1 DUF1743 PF08489.11 OAP56949.1 - 0.09 12.8 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1743) API5 PF05918.11 OAP56949.1 - 0.59 8.9 3.5 0.86 8.3 3.5 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) FXMRP1_C_core PF12235.8 OAP56949.1 - 0.84 10.3 6.4 0.25 12.0 2.6 2.3 2 0 0 2 2 2 0 Fragile X-related 1 protein core C terminal MARVEL PF01284.23 OAP56950.1 - 1.5e-10 41.3 6.7 2e-10 40.8 6.7 1.2 1 0 0 1 1 1 1 Membrane-associating domain SH3_1 PF00018.28 OAP56951.1 - 2.1e-09 36.9 0.5 5.5e-09 35.5 0.1 1.8 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 OAP56951.1 - 7.4e-07 28.9 0.0 1.3e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 OAP56951.1 - 1.1e-05 25.1 0.0 1.9e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain YhhN PF07947.14 OAP56951.1 - 0.0035 17.0 12.0 0.0049 16.5 12.0 1.2 1 0 0 1 1 1 1 YhhN family TMEM220 PF15071.6 OAP56951.1 - 0.015 16.1 4.3 0.029 15.1 4.3 1.5 1 1 0 1 1 1 0 Transmembrane family 220, helix DUF2569 PF10754.9 OAP56951.1 - 0.11 12.9 10.9 0.31 11.5 10.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2569) DUF1129 PF06570.11 OAP56951.1 - 2.9 7.3 10.6 0.11 11.9 4.5 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) DUF2530 PF10745.9 OAP56951.1 - 7.7 6.8 7.1 2 8.7 3.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2530) Dynactin_p22 PF07426.11 OAP56952.1 - 1.8e-05 24.7 0.0 3.6e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Dynactin subunit p22 HALZ PF02183.18 OAP56952.1 - 0.98 9.7 3.7 0.42 10.9 0.5 2.0 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF4140 PF13600.6 OAP56952.1 - 1.7 9.1 5.3 0.44 11.0 0.7 2.3 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) Bot1p PF12298.8 OAP56954.1 - 2.1e-15 57.3 0.2 2.1e-15 57.3 0.2 2.6 2 1 1 3 3 3 1 Eukaryotic mitochondrial regulator protein NTPase_P4 PF11602.8 OAP56954.1 - 0.045 13.0 0.0 0.072 12.3 0.0 1.2 1 0 0 1 1 1 0 ATPase P4 of dsRNA bacteriophage phi-12 Glyco_hydro_43 PF04616.14 OAP56955.1 - 5.9e-26 91.4 0.0 8e-26 91.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 MFS_1 PF07690.16 OAP56956.1 - 8.2e-35 120.4 20.6 8.2e-35 120.4 20.6 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily YfhO PF09586.10 OAP56956.1 - 0.0093 14.3 0.2 0.044 12.0 0.3 1.9 2 0 0 2 2 2 1 Bacterial membrane protein YfhO Deltaretro_Tax PF05599.11 OAP56956.1 - 0.08 13.5 0.0 0.2 12.2 0.0 1.6 1 0 0 1 1 1 0 Deltaretrovirus Tax protein GFO_IDH_MocA PF01408.22 OAP56957.1 - 1.1e-24 87.6 0.0 1.8e-24 86.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 OAP56957.1 - 7.4e-09 35.6 0.3 2.3e-08 34.0 0.0 2.0 3 0 0 3 3 3 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 OAP56957.1 - 3.8e-05 24.3 0.2 6.6e-05 23.5 0.2 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DapB_N PF01113.20 OAP56957.1 - 0.0046 17.1 0.2 0.0079 16.3 0.2 1.3 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.24 OAP56957.1 - 0.042 14.3 0.0 0.067 13.6 0.0 1.3 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Redoxin PF08534.10 OAP56957.1 - 0.074 12.8 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Redoxin CALM_bind PF16025.5 OAP56958.1 - 0.082 13.4 4.4 0.19 12.2 4.4 1.6 1 0 0 1 1 1 0 Calcium-dependent calmodulin binding Zwint PF15556.6 OAP56958.1 - 0.62 9.5 4.1 0.93 8.9 4.1 1.2 1 0 0 1 1 1 0 ZW10 interactor PNP_UDP_1 PF01048.20 OAP56959.1 - 3e-07 29.9 2.7 1.4e-06 27.7 2.7 2.0 1 1 0 1 1 1 1 Phosphorylase superfamily Ank_2 PF12796.7 OAP56960.1 - 2.4e-29 101.7 6.0 1.8e-10 41.3 0.1 3.9 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAP56960.1 - 9.8e-26 89.8 4.8 4.5e-05 23.9 0.0 7.1 1 1 6 7 7 7 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 OAP56960.1 - 3.1e-21 75.2 3.3 0.00053 20.2 0.1 6.3 2 2 4 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 OAP56960.1 - 3.3e-19 68.4 16.4 0.04 14.4 0.1 8.2 8 0 0 8 8 8 6 Ankyrin repeat Ank_3 PF13606.6 OAP56960.1 - 2.9e-13 48.7 3.7 1.5 9.6 0.0 8.8 8 0 0 8 8 8 1 Ankyrin repeat NACHT PF05729.12 OAP56960.1 - 3.7e-07 30.2 0.1 8.8e-07 29.0 0.1 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 OAP56960.1 - 0.00013 22.4 5.2 0.00043 20.7 0.0 3.6 3 2 0 3 3 3 1 AAA ATPase domain KAP_NTPase PF07693.14 OAP56960.1 - 0.0029 16.9 0.7 1.8 7.7 0.2 2.8 2 1 1 3 3 3 2 KAP family P-loop domain AAA_22 PF13401.6 OAP56960.1 - 0.0082 16.4 0.0 0.027 14.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain Apolipoprotein PF01442.18 OAP56960.1 - 0.015 15.2 6.0 0.011 15.7 2.7 2.5 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain AAA PF00004.29 OAP56960.1 - 0.021 15.3 0.0 0.061 13.8 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF4417 PF14386.6 OAP56960.1 - 0.033 13.8 0.0 8 6.0 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4417) AAA_18 PF13238.6 OAP56960.1 - 0.064 13.8 0.1 0.53 10.8 0.1 2.6 1 1 0 1 1 1 0 AAA domain cobW PF02492.19 OAP56960.1 - 0.072 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DAP3 PF10236.9 OAP56960.1 - 0.15 11.2 0.0 0.28 10.3 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Arg_repressor PF01316.21 OAP56960.1 - 1.1 9.1 6.9 1.7e+02 2.0 0.1 5.3 5 0 0 5 5 5 0 Arginine repressor, DNA binding domain TPR_12 PF13424.6 OAP56961.1 - 1.4e-15 57.4 7.3 3.5e-07 30.4 0.2 4.5 4 1 1 5 5 4 3 Tetratricopeptide repeat NB-ARC PF00931.22 OAP56961.1 - 2.6e-12 46.5 0.0 4.4e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 OAP56961.1 - 4.9e-07 30.3 0.1 4.4e-06 27.2 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain TPR_10 PF13374.6 OAP56961.1 - 8.6e-06 25.5 10.6 0.14 12.1 0.1 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_MalT PF17874.1 OAP56961.1 - 9.1e-05 22.0 1.0 0.16 11.3 0.2 2.3 1 1 1 2 2 2 2 MalT-like TPR region TPR_1 PF00515.28 OAP56961.1 - 0.00012 21.8 15.6 0.87 9.5 0.0 5.6 6 0 0 6 6 6 3 Tetratricopeptide repeat ATPase_2 PF01637.18 OAP56961.1 - 0.00027 20.9 0.0 0.00055 19.9 0.0 1.5 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea TPR_8 PF13181.6 OAP56961.1 - 0.0035 17.4 5.2 22 5.6 0.1 5.9 5 1 0 5 5 5 0 Tetratricopeptide repeat AAA_25 PF13481.6 OAP56961.1 - 0.016 14.8 0.0 0.039 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 OAP56961.1 - 0.023 15.0 0.0 0.086 13.1 0.0 2.0 1 0 0 1 1 1 0 AAA domain TPR_2 PF07719.17 OAP56961.1 - 0.045 13.9 12.3 6.4 7.1 0.1 5.6 5 0 0 5 5 5 0 Tetratricopeptide repeat Viral_helicase1 PF01443.18 OAP56961.1 - 0.1 12.3 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ANAPC3 PF12895.7 OAP56961.1 - 0.18 12.0 3.3 0.28 11.4 0.3 2.9 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 OAP56961.1 - 0.48 10.6 8.3 1.3 9.2 0.2 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat APH PF01636.23 OAP56962.1 - 9.1e-06 25.8 1.3 0.079 12.9 0.1 3.0 2 1 0 2 2 2 2 Phosphotransferase enzyme family EcKinase PF02958.20 OAP56962.1 - 0.0019 17.6 0.0 0.56 9.5 0.0 3.0 3 0 0 3 3 3 1 Ecdysteroid kinase Choline_kinase PF01633.20 OAP56962.1 - 0.047 13.3 0.0 0.075 12.6 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF1463 PF07316.11 OAP56962.1 - 0.15 11.9 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1463) DUF3215 PF11503.8 OAP56963.1 - 0.077 12.9 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3215) DAO PF01266.24 OAP56964.1 - 1.4e-09 38.0 0.0 6.2e-09 35.9 0.0 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase MFS_1 PF07690.16 OAP56965.1 - 2.2e-22 79.4 24.0 3.6e-22 78.8 24.0 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily PUCC PF03209.15 OAP56965.1 - 0.0011 18.0 11.4 0.0043 16.1 11.4 1.8 1 1 0 1 1 1 1 PUCC protein DUF3236 PF11576.8 OAP56965.1 - 0.074 12.8 0.5 0.13 12.0 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3236) PAP_assoc PF03828.19 OAP56966.1 - 3.4e-17 62.4 0.1 1.1e-16 60.7 0.1 2.0 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 OAP56966.1 - 1e-07 32.2 0.0 1.7e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 OAP56966.1 - 0.0011 19.0 0.0 0.002 18.2 0.0 1.4 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase SE PF08491.10 OAP56967.1 - 3.2e-104 347.8 0.0 4.4e-104 347.4 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.19 OAP56967.1 - 1e-11 44.7 0.0 1.1e-08 34.7 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 OAP56967.1 - 3.5e-08 33.4 0.2 1.2e-06 28.4 0.2 2.3 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OAP56967.1 - 6.7e-05 22.1 1.6 0.0005 19.3 1.1 2.0 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 OAP56967.1 - 0.00017 21.7 0.4 0.00043 20.4 0.4 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAP56967.1 - 0.00094 18.5 0.0 0.0015 17.9 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OAP56967.1 - 0.00097 18.3 0.1 0.022 13.9 0.1 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 OAP56967.1 - 0.0012 18.3 0.1 0.0015 18.0 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 OAP56967.1 - 0.0027 17.0 0.1 0.014 14.6 0.0 1.9 2 0 0 2 2 2 1 Thi4 family ApbA PF02558.16 OAP56967.1 - 0.0036 17.0 0.1 0.0077 15.9 0.1 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 OAP56967.1 - 0.0037 17.2 0.1 0.0078 16.1 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.27 OAP56967.1 - 0.0098 16.4 0.2 0.02 15.4 0.2 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OAP56967.1 - 0.036 13.1 0.5 0.11 11.5 0.3 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein HI0933_like PF03486.14 OAP56967.1 - 0.058 12.1 0.2 0.083 11.6 0.2 1.1 1 0 0 1 1 1 0 HI0933-like protein Shikimate_DH PF01488.20 OAP56967.1 - 0.075 13.1 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.14 OAP56967.1 - 0.079 12.5 0.1 0.12 11.9 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ThiF PF00899.21 OAP56967.1 - 0.087 12.2 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 ThiF family TrkA_N PF02254.18 OAP56967.1 - 0.089 13.1 0.1 0.17 12.1 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain AlaDh_PNT_C PF01262.21 OAP56967.1 - 0.12 11.6 0.1 0.25 10.6 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Trp_halogenase PF04820.14 OAP56967.1 - 0.15 10.9 0.1 0.25 10.2 0.1 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Lactamase_B PF00753.27 OAP56968.1 - 5.3e-12 46.2 7.3 9.9e-12 45.3 7.3 1.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OAP56968.1 - 1.3e-05 24.9 0.6 2.2e-05 24.1 0.6 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 OAP56968.1 - 0.14 12.1 0.5 0.39 10.6 0.1 2.0 2 0 0 2 2 2 0 Beta-lactamase superfamily domain DIOX_N PF14226.6 OAP56969.1 - 1e-23 84.3 1.5 2.6e-23 83.0 1.5 1.7 1 1 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OAP56969.1 - 1.9e-18 66.8 0.0 5.2e-18 65.4 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF2439 PF10382.9 OAP56970.1 - 5.1e-25 87.6 0.2 8.7e-25 86.9 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) DUF1096 PF06493.11 OAP56970.1 - 0.054 14.0 1.2 0.28 11.7 1.2 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1096) SH3_9 PF14604.6 OAP56971.1 - 1.2e-14 53.8 0.1 2.6e-14 52.8 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 OAP56971.1 - 8.2e-14 50.9 0.1 1.5e-13 50.1 0.1 1.5 1 0 0 1 1 1 1 SH3 domain BAR PF03114.18 OAP56971.1 - 2.7e-12 46.8 4.7 4.3e-12 46.2 4.7 1.4 1 1 0 1 1 1 1 BAR domain SH3_2 PF07653.17 OAP56971.1 - 1.5e-09 37.4 0.0 2.6e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain T3SS_basalb_I PF17001.5 OAP56971.1 - 0.092 13.3 0.8 1.4 9.5 0.9 2.3 1 1 1 2 2 2 0 Type III secretion basal body protein I, YscI, HrpB, PscI Fib_alpha PF08702.10 OAP56971.1 - 0.14 12.4 2.8 0.29 11.3 2.8 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family GAS PF13851.6 OAP56971.1 - 1.1 8.5 10.7 3.8 6.8 7.6 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding ABC_tran PF00005.27 OAP56972.1 - 8.8e-15 55.4 0.2 2.1e-13 51.0 0.2 2.1 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 OAP56972.1 - 2.7e-11 43.9 0.8 0.00013 21.9 0.2 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF3584 PF12128.8 OAP56972.1 - 0.0018 15.9 0.3 0.0024 15.5 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) AAA_29 PF13555.6 OAP56972.1 - 0.002 17.8 0.1 0.0039 16.9 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 OAP56972.1 - 0.006 17.1 0.1 0.0088 16.6 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 OAP56972.1 - 0.011 15.3 0.1 0.023 14.3 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 OAP56972.1 - 0.012 15.3 0.1 0.017 14.8 0.1 1.1 1 0 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.9 OAP56972.1 - 0.015 15.0 0.0 0.022 14.5 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.6 OAP56972.1 - 0.043 14.1 0.2 0.078 13.2 0.2 1.4 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 OAP56972.1 - 0.045 13.6 0.0 0.067 13.1 0.0 1.2 1 0 0 1 1 1 0 RsgA GTPase SMC_N PF02463.19 OAP56972.1 - 0.06 12.8 0.0 5 6.5 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain SRP54 PF00448.22 OAP56972.1 - 0.08 12.6 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_22 PF13401.6 OAP56972.1 - 0.082 13.2 0.0 0.14 12.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 OAP56972.1 - 0.1 13.1 0.6 0.78 10.3 0.6 2.2 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 OAP56972.1 - 0.11 12.8 0.1 0.23 11.8 0.1 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_13 PF13166.6 OAP56972.1 - 0.15 10.7 0.1 0.2 10.3 0.1 1.1 1 0 0 1 1 1 0 AAA domain DLIC PF05783.11 OAP56972.1 - 0.19 10.5 0.1 0.29 9.9 0.1 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Phi-29_GP4 PF05464.11 OAP56972.1 - 0.19 12.0 0.1 0.3 11.4 0.1 1.3 1 0 0 1 1 1 0 Phi-29-like late genes activator (early protein GP4) Arf PF00025.21 OAP56972.1 - 0.19 11.2 0.1 0.44 10.0 0.0 1.6 2 0 0 2 2 2 0 ADP-ribosylation factor family Roc PF08477.13 OAP56972.1 - 0.2 11.9 0.0 0.35 11.1 0.0 1.3 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_5 PF07728.14 OAP56972.1 - 0.23 11.4 0.7 1.9 8.5 0.2 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) WD40 PF00400.32 OAP56973.1 - 1.6e-30 104.6 32.0 7.9e-05 23.4 0.1 12.9 14 0 0 14 14 14 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAP56973.1 - 1.6e-09 37.9 3.2 0.79 10.1 0.1 7.1 6 1 0 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OAP56973.1 - 2.6e-05 23.4 0.0 4.3 6.2 0.0 5.2 5 1 0 6 6 6 3 WD40 region of Ge1, enhancer of mRNA-decapping protein RTA1 PF04479.13 OAP56974.1 - 9e-46 156.1 4.1 1.1e-45 155.8 4.1 1.0 1 0 0 1 1 1 1 RTA1 like protein Urm1 PF09138.11 OAP56976.1 - 3.9e-34 116.9 0.0 4.4e-34 116.7 0.0 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.20 OAP56976.1 - 0.068 13.8 0.0 0.083 13.5 0.0 1.2 1 0 0 1 1 1 0 ThiS family 6PF2K PF01591.18 OAP56977.1 - 2.2e-61 207.0 0.0 3.4e-61 206.4 0.0 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 OAP56977.1 - 9e-20 71.2 0.2 3.7e-19 69.2 0.2 1.9 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Porin_3 PF01459.22 OAP56978.1 - 1.3e-75 254.4 0.0 1.6e-75 254.1 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic porin Zds_C PF08632.10 OAP56978.1 - 0.0042 16.8 0.0 0.0097 15.6 0.0 1.6 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term Pkinase PF00069.25 OAP56979.1 - 2e-65 220.8 0.0 2.4e-65 220.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP56979.1 - 4.2e-25 88.5 0.0 5.5e-25 88.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAP56979.1 - 1.7e-06 27.6 0.0 1.1e-05 24.9 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 OAP56979.1 - 0.001 19.1 0.2 0.0079 16.1 0.0 2.3 2 1 1 3 3 3 1 Phosphotransferase enzyme family DUF1229 PF06797.11 OAP56979.1 - 0.023 14.9 0.2 0.036 14.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1229) Kdo PF06293.14 OAP56979.1 - 0.13 11.5 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MIF4G_like PF09088.11 OAP56980.1 - 1.1e-89 299.2 0.2 1.7e-89 298.7 0.2 1.2 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.11 OAP56980.1 - 5.5e-70 235.9 0.1 7.8e-70 235.4 0.1 1.2 1 0 0 1 1 1 1 MIF4G like MIF4G PF02854.19 OAP56980.1 - 6.4e-05 22.7 0.0 0.00022 21.0 0.0 1.8 2 0 0 2 2 2 1 MIF4G domain RRM_1 PF00076.22 OAP56982.1 - 2.5e-37 126.5 0.0 1.2e-17 63.5 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OAP56982.1 - 0.00025 21.1 0.0 0.027 14.6 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif RRM_5 PF13893.6 OAP56982.1 - 0.00034 20.2 0.0 0.018 14.6 0.0 2.2 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.11 OAP56982.1 - 0.012 15.3 0.1 6.2 6.6 0.0 2.5 2 0 0 2 2 2 0 Ribonuclease B OB domain PHM7_cyt PF14703.6 OAP56982.1 - 0.012 15.9 0.1 0.38 11.0 0.0 2.2 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter Limkain-b1 PF11608.8 OAP56982.1 - 0.036 14.1 0.4 1.2 9.3 0.1 2.2 2 0 0 2 2 2 0 Limkain b1 RRM_occluded PF16842.5 OAP56982.1 - 0.045 13.6 0.0 0.081 12.8 0.0 1.4 1 0 0 1 1 1 0 Occluded RNA-recognition motif Tom7 PF08038.12 OAP56983.1 - 2.3e-13 49.6 0.0 2.4e-13 49.5 0.0 1.1 1 0 0 1 1 1 1 TOM7 family Sigma70_r4 PF04545.16 OAP56983.1 - 0.094 12.2 0.1 0.23 11.0 0.1 1.6 2 0 0 2 2 2 0 Sigma-70, region 4 WD40 PF00400.32 OAP56984.1 - 2.6e-60 198.9 9.5 5.9e-09 36.4 0.1 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAP56984.1 - 1.1e-18 67.3 0.0 1.4e-05 25.3 0.0 6.4 1 1 6 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Tup_N PF08581.10 OAP56984.1 - 1.6e-16 60.4 11.6 2.9e-16 59.5 11.6 1.4 1 0 0 1 1 1 1 Tup N-terminal WD40_like PF17005.5 OAP56984.1 - 2.7e-08 33.5 0.0 0.0023 17.3 0.0 4.8 3 1 2 5 5 5 1 WD40-like domain Ge1_WD40 PF16529.5 OAP56984.1 - 2.8e-06 26.5 0.0 1.7 7.5 0.0 4.7 1 1 3 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 OAP56984.1 - 2.9e-05 23.6 0.1 0.048 13.0 0.0 2.9 2 1 1 3 3 3 2 Neuroblastoma-amplified sequence, N terminal eIF2A PF08662.11 OAP56984.1 - 0.00035 20.5 0.0 0.085 12.7 0.0 3.2 1 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Peptidase_S9_N PF02897.15 OAP56984.1 - 0.00067 18.6 0.0 0.032 13.0 0.0 2.9 2 1 1 3 3 3 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Nup160 PF11715.8 OAP56984.1 - 0.0028 16.4 0.1 4.9 5.7 0.0 3.2 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 OAP56984.1 - 0.0039 15.8 0.2 0.022 13.3 0.2 2.1 1 1 0 2 2 2 1 Cytochrome D1 heme domain Nucleoporin_N PF08801.11 OAP56984.1 - 0.014 14.1 0.2 7.9 5.1 0.1 3.7 2 1 2 4 4 4 0 Nup133 N terminal like VID27 PF08553.10 OAP56984.1 - 0.23 10.5 0.0 5.7 5.9 0.0 2.6 1 1 2 3 3 3 0 VID27 C-terminal WD40-like domain Golgin_A5 PF09787.9 OAP56984.1 - 0.76 9.2 8.5 1.1 8.7 8.5 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 Proteasome_A_N PF10584.9 OAP56984.1 - 1.2 8.9 5.7 7.6 6.3 0.0 4.4 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature zf-C2H2 PF00096.26 OAP56985.1 - 1.1e-11 44.4 15.9 0.0013 19.1 2.8 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OAP56985.1 - 8.7e-07 29.1 1.1 8.7e-07 29.1 1.1 4.6 4 1 0 4 4 4 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 OAP56985.1 - 8.9e-06 26.1 13.9 0.071 14.0 0.5 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_8 PF15909.5 OAP56985.1 - 0.0016 18.7 1.3 0.0036 17.6 0.9 1.9 1 1 0 1 1 1 1 C2H2-type zinc ribbon zf-met PF12874.7 OAP56985.1 - 0.0074 16.6 0.4 0.34 11.3 0.1 3.2 3 0 0 3 3 3 1 Zinc-finger of C2H2 type FOXP-CC PF16159.5 OAP56985.1 - 0.081 13.6 5.1 0.74 10.5 1.1 3.2 2 1 0 2 2 2 0 FOXP coiled-coil domain Mito_carr PF00153.27 OAP56986.1 - 1.3e-64 214.2 0.4 2.3e-20 72.3 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein FA_hydroxylase PF04116.13 OAP56987.1 - 4.5e-25 88.5 18.9 1.7e-24 86.6 16.6 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF2015 PF09435.10 OAP56988.1 - 1.8e-44 150.1 0.0 2.2e-44 149.9 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) Ribosomal_L28e PF01778.17 OAP56989.1 - 3e-35 121.4 0.9 3.7e-35 121.2 0.9 1.1 1 0 0 1 1 1 1 Ribosomal L28e protein family Ldh_1_C PF02866.18 OAP56990.1 - 5.6e-46 156.5 0.0 9.4e-46 155.8 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 OAP56990.1 - 4.1e-41 140.4 0.1 3.5e-40 137.4 0.1 2.0 1 1 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 OAP56990.1 - 0.0073 15.3 0.0 0.021 13.9 0.0 1.8 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family SMBP PF16785.5 OAP56990.1 - 0.1 12.8 0.2 0.21 11.8 0.2 1.5 1 0 0 1 1 1 0 Small metal-binding protein Glyco_hydro_4 PF02056.16 OAP56990.1 - 0.11 12.0 0.5 12 5.4 0.0 2.3 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase NAD_binding_10 PF13460.6 OAP56990.1 - 0.13 12.1 0.3 0.44 10.4 0.0 2.1 3 0 0 3 3 3 0 NAD(P)H-binding TRAPP PF04051.16 OAP56991.1 - 5e-37 126.9 0.0 6.4e-37 126.5 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Sec16_C PF12931.7 OAP56992.1 - 8e-109 363.9 0.0 1.1e-108 363.5 0.0 1.2 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.7 OAP56992.1 - 9.4e-31 106.9 0.0 2.2e-30 105.7 0.0 1.7 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region Sec16_N PF12935.7 OAP56992.1 - 5.1e-10 39.9 20.4 5.1e-10 39.9 20.4 4.0 3 1 1 4 4 4 1 Vesicle coat trafficking protein Sec16 N-terminus PhoLip_ATPase_C PF16212.5 OAP56993.1 - 9.3e-52 176.2 3.7 9.3e-52 176.2 3.7 2.4 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 OAP56993.1 - 7.2e-17 60.8 1.6 1.4e-16 59.9 1.6 1.5 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 OAP56993.1 - 1.3e-11 45.2 6.4 5.3e-07 30.1 3.9 3.5 3 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 OAP56993.1 - 2.5e-06 27.1 0.7 2.5e-06 27.1 0.7 2.5 2 1 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 OAP56993.1 - 8.7e-06 25.7 0.0 0.00012 22.1 0.0 2.6 2 1 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 OAP56993.1 - 0.0056 16.4 0.0 0.013 15.3 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Mso1_Sec1_bdg PF14475.6 OAP56994.1 - 4.7e-13 48.5 0.1 8.6e-13 47.7 0.1 1.4 1 0 0 1 1 1 1 Sec1-binding region of Mso1 AMP_N PF05195.16 OAP56995.1 - 0.047 13.4 0.0 0.095 12.4 0.0 1.5 1 0 0 1 1 1 0 Aminopeptidase P, N-terminal domain DUF892 PF05974.12 OAP56995.1 - 0.063 13.3 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF892) YIF1 PF03878.15 OAP56996.1 - 1.5e-98 329.1 6.6 1.8e-98 328.9 6.6 1.0 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.17 OAP56996.1 - 0.00029 20.6 8.3 0.00029 20.6 8.3 1.7 2 0 0 2 2 2 1 Yip1 domain PLAC8 PF04749.17 OAP56997.1 - 3.2e-23 82.6 15.5 4.1e-23 82.2 15.5 1.1 1 0 0 1 1 1 1 PLAC8 family Vps55 PF04133.14 OAP56997.1 - 0.081 12.9 0.1 0.11 12.5 0.1 1.2 1 0 0 1 1 1 0 Vacuolar protein sorting 55 Lactamase_B PF00753.27 OAP56998.1 - 7.9e-08 32.5 4.2 5.1e-07 29.9 4.2 2.3 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OAP56998.1 - 0.014 15.0 0.0 0.028 13.9 0.0 1.5 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Lipocalin_5 PF13924.6 OAP56999.1 - 3.4e-16 59.3 0.0 3.8e-16 59.2 0.0 1.0 1 0 0 1 1 1 1 Lipocalin-like domain Aldedh PF00171.22 OAP57000.1 - 8e-150 499.4 0.1 1.8e-149 498.2 0.1 1.5 1 1 0 1 1 1 1 Aldehyde dehydrogenase family Halo_GVPC PF05465.13 OAP57000.1 - 0.051 13.8 2.0 0.15 12.4 2.0 1.8 1 0 0 1 1 1 0 Halobacterial gas vesicle protein C (GVPC) repeat FAD_binding_2 PF00890.24 OAP57001.1 - 2.4e-35 122.4 0.3 1.2e-34 120.1 0.3 1.8 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 OAP57001.1 - 1.7e-07 31.0 0.2 3e-06 26.9 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAP57001.1 - 8e-06 25.3 0.2 0.11 11.7 0.0 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAP57001.1 - 1.5e-05 24.8 2.1 1.5e-05 24.8 2.1 2.5 3 1 0 3 3 3 1 FAD dependent oxidoreductase HI0933_like PF03486.14 OAP57001.1 - 8.3e-05 21.4 5.0 0.033 12.9 0.2 3.2 3 0 0 3 3 3 3 HI0933-like protein GMC_oxred_N PF00732.19 OAP57001.1 - 0.003 17.0 0.0 0.0091 15.4 0.0 1.7 1 0 0 1 1 1 1 GMC oxidoreductase GIDA PF01134.22 OAP57001.1 - 0.0084 15.2 0.5 0.0084 15.2 0.5 2.6 3 0 0 3 3 3 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 OAP57001.1 - 0.029 13.6 0.0 0.047 12.9 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_binding_8 PF13450.6 OAP57001.1 - 0.033 14.4 0.4 0.13 12.5 0.4 2.1 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 OAP57001.1 - 0.048 14.2 0.3 19 5.9 0.0 3.2 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 OAP57001.1 - 0.057 12.7 0.0 0.16 11.2 0.0 1.8 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 OAP57001.1 - 0.065 12.5 0.2 0.31 10.3 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase adh_short_C2 PF13561.6 OAP57002.1 - 1.1e-56 192.0 0.1 1.3e-56 191.7 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP57002.1 - 1.1e-46 158.8 0.5 1.4e-46 158.4 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAP57002.1 - 2.4e-11 43.9 0.2 3e-11 43.6 0.2 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAP57002.1 - 0.027 13.9 0.3 0.041 13.3 0.3 1.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 OAP57002.1 - 0.13 12.1 0.5 0.18 11.7 0.5 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Oxysterol_BP PF01237.18 OAP57003.1 - 2.3e-58 197.8 0.4 4.9e-51 173.7 0.0 2.0 1 1 1 2 2 2 2 Oxysterol-binding protein DnaT PF17948.1 OAP57003.1 - 0.074 12.8 0.8 0.32 10.7 0.0 2.5 3 0 0 3 3 3 0 DnaT DNA-binding domain MOSC PF03473.17 OAP57004.1 - 6.1e-25 87.7 0.0 1.4e-24 86.6 0.0 1.6 2 0 0 2 2 2 1 MOSC domain MOSC_N PF03476.16 OAP57004.1 - 4.3e-18 65.3 0.0 7.8e-18 64.5 0.0 1.4 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain Cuticle_1 PF08140.11 OAP57004.1 - 0.06 13.4 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 Crustacean cuticle protein repeat Zn_clus PF00172.18 OAP57005.1 - 3.2e-10 40.0 9.4 5.4e-10 39.2 9.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 OAP57005.1 - 9.7e-08 31.2 2.2 0.0029 16.5 0.6 3.0 2 1 0 2 2 2 2 Fungal specific transcription factor domain Lactonase PF10282.9 OAP57006.1 - 1.1e-06 28.2 2.3 3.5e-05 23.2 1.5 3.2 2 1 1 3 3 3 1 Lactonase, 7-bladed beta-propeller Cytochrom_D1 PF02239.16 OAP57006.1 - 0.0011 17.6 3.1 0.016 13.7 1.9 2.9 1 1 1 2 2 2 1 Cytochrome D1 heme domain PD40 PF07676.12 OAP57006.1 - 0.052 13.5 0.1 22 5.1 0.0 4.3 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat HET PF06985.11 OAP57007.1 - 3.8e-09 37.0 0.1 7.4e-09 36.1 0.1 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Catalase PF00199.19 OAP57008.1 - 6.1e-193 641.1 0.4 9.8e-193 640.5 0.4 1.3 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 OAP57008.1 - 2.8e-12 46.7 0.1 7.2e-12 45.3 0.1 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive Arrestin_C PF02752.22 OAP57009.1 - 0.03 14.8 0.2 0.076 13.5 0.2 1.7 1 1 0 1 1 1 0 Arrestin (or S-antigen), C-terminal domain Adap_comp_sub PF00928.21 OAP57010.1 - 8.4e-84 281.0 0.0 1.1e-83 280.7 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 OAP57010.1 - 1.5e-05 24.9 0.2 2.7e-05 24.1 0.2 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Myb_DNA-bind_6 PF13921.6 OAP57011.1 - 0.03 14.6 0.0 0.054 13.7 0.0 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain DUF1996 PF09362.10 OAP57012.1 - 4.5e-74 249.4 0.9 7.3e-74 248.7 0.9 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) WSC PF01822.19 OAP57012.1 - 7.4e-60 199.1 65.8 1.1e-16 60.7 13.5 4.5 4 0 0 4 4 4 4 WSC domain DUF2423 PF10338.9 OAP57014.1 - 8.8e-18 64.3 4.5 8.8e-18 64.3 4.5 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF2423) Roughex PF06020.11 OAP57014.1 - 0.029 13.5 2.9 0.031 13.4 2.9 1.0 1 0 0 1 1 1 0 Drosophila roughex protein PINIT PF14324.6 OAP57015.1 - 4.8e-35 121.0 0.0 7.7e-35 120.4 0.0 1.3 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.20 OAP57015.1 - 1.1e-19 70.0 1.6 1.7e-19 69.2 1.6 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger SAP PF02037.27 OAP57015.1 - 1.4e-06 27.9 0.3 2.5e-06 27.1 0.3 1.4 1 0 0 1 1 1 1 SAP domain zf-Nse PF11789.8 OAP57015.1 - 0.044 13.6 0.2 0.12 12.2 0.1 1.8 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Vps36-NZF-N PF16988.5 OAP57015.1 - 0.048 13.0 0.1 0.12 11.8 0.1 1.6 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-Sec23_Sec24 PF04810.15 OAP57015.1 - 0.11 12.5 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger DUF3890 PF13029.6 OAP57015.1 - 0.22 12.0 0.2 0.59 10.6 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3890) Methyltransf_31 PF13847.6 OAP57016.1 - 1.8e-15 57.1 0.0 7.1e-15 55.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAP57016.1 - 8e-07 29.7 0.0 2.1e-06 28.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAP57016.1 - 1.1e-05 25.4 0.0 3.6e-05 23.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAP57016.1 - 0.00015 22.3 0.2 0.0021 18.7 0.1 2.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAP57016.1 - 0.0014 19.3 0.0 0.0055 17.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 OAP57016.1 - 0.027 14.5 0.0 0.065 13.2 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.14 OAP57016.1 - 0.067 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Rsm22 PF09243.10 OAP57016.1 - 0.15 11.3 0.0 0.23 10.7 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 SRP-alpha_N PF04086.13 OAP57017.1 - 1.7e-74 251.4 0.0 2.1e-74 251.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.22 OAP57017.1 - 3.3e-48 163.9 0.1 5.6e-48 163.2 0.1 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.19 OAP57017.1 - 1.5e-08 34.7 0.0 6.5e-08 32.7 0.0 2.1 2 0 0 2 2 1 1 SRP54-type protein, helical bundle domain MeaB PF03308.16 OAP57017.1 - 2.2e-07 30.1 0.0 4.2e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_24 PF13479.6 OAP57017.1 - 0.00017 21.4 0.0 0.017 14.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 OAP57017.1 - 0.0048 17.0 1.1 0.044 13.9 1.1 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_30 PF13604.6 OAP57017.1 - 0.0081 15.9 0.1 0.0081 15.9 0.1 2.0 3 0 0 3 3 2 1 AAA domain CbiA PF01656.23 OAP57017.1 - 0.014 15.4 4.8 0.3 11.1 0.0 3.1 2 1 1 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain ABC_tran PF00005.27 OAP57017.1 - 0.02 15.4 0.1 0.25 11.9 0.0 2.4 2 0 0 2 2 2 0 ABC transporter AAA_17 PF13207.6 OAP57017.1 - 0.022 15.2 0.0 0.073 13.5 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_31 PF13614.6 OAP57017.1 - 0.054 13.4 0.1 0.27 11.1 0.0 1.9 1 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 OAP57017.1 - 0.086 13.2 0.0 0.21 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain Longin PF13774.6 OAP57017.1 - 0.11 12.6 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Regulated-SNARE-like domain APS_kinase PF01583.20 OAP57017.1 - 0.15 12.0 0.0 0.36 10.7 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase DUF87 PF01935.17 OAP57017.1 - 4.6 7.3 6.4 0.88 9.6 0.1 2.6 2 1 1 3 3 3 0 Helicase HerA, central domain AIM24 PF01987.17 OAP57018.1 - 9.8e-48 162.6 0.3 1.1e-47 162.4 0.3 1.0 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 Peptidase_S41 PF03572.18 OAP57019.1 - 2.7e-08 33.6 0.0 6.9e-08 32.2 0.0 1.6 1 1 0 1 1 1 1 Peptidase family S41 SR-25 PF10500.9 OAP57020.1 - 2.7e-05 23.9 6.2 4.5e-05 23.2 6.2 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein SOG2 PF10428.9 OAP57020.1 - 0.028 13.6 8.4 0.037 13.2 8.4 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein FAM199X PF15814.5 OAP57020.1 - 0.22 10.5 5.9 0.33 10.0 5.9 1.2 1 0 0 1 1 1 0 Protein family FAM199X Apt1 PF10351.9 OAP57020.1 - 2.2 7.0 7.4 3.1 6.5 7.4 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain TPR_12 PF13424.6 OAP57021.1 - 1.2e-10 41.5 0.6 1.7e-07 31.4 0.1 3.6 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 OAP57021.1 - 6.9e-08 32.0 0.8 0.28 11.4 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.6 OAP57021.1 - 1.7e-06 27.7 1.8 0.11 12.4 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 OAP57021.1 - 4.4e-06 27.2 3.3 0.00043 20.9 0.2 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 OAP57021.1 - 5.2e-06 26.9 0.3 0.00049 20.5 0.0 2.6 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 OAP57021.1 - 0.00017 22.1 7.8 0.04 14.8 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_4 PF07721.14 OAP57021.1 - 0.0037 17.7 5.0 1.5 9.7 0.2 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat PPR_1 PF12854.7 OAP57021.1 - 0.012 15.3 1.0 0.17 11.6 0.2 2.3 2 0 0 2 2 2 0 PPR repeat TPR_7 PF13176.6 OAP57021.1 - 0.078 13.0 2.2 1.5 9.0 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat PPR PF01535.20 OAP57021.1 - 0.13 12.5 0.2 24 5.4 0.1 2.9 3 0 0 3 3 3 0 PPR repeat TPR_6 PF13174.6 OAP57021.1 - 1.9 9.3 4.0 14 6.6 0.1 3.2 4 0 0 4 4 3 0 Tetratricopeptide repeat DUF1479 PF07350.12 OAP57023.1 - 5.6e-162 539.2 0.0 6.6e-162 539.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) adh_short PF00106.25 OAP57024.1 - 2.4e-34 118.5 0.0 3.4e-34 118.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP57024.1 - 7e-31 107.6 0.0 1.2e-30 106.8 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP57024.1 - 9.5e-06 25.6 0.0 1.8e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 KR domain Ank_2 PF12796.7 OAP57024.1 - 0.047 14.3 0.2 36 5.1 0.0 3.2 2 2 0 2 2 2 0 Ankyrin repeats (3 copies) 2-Hacid_dh_C PF02826.19 OAP57024.1 - 0.13 11.7 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Aa_trans PF01490.18 OAP57025.1 - 3.7e-94 315.8 13.8 3.7e-94 315.8 13.8 1.6 2 0 0 2 2 2 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 OAP57025.1 - 0.00017 20.8 18.3 0.00017 20.8 18.3 1.8 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family Bax1-I PF01027.20 OAP57026.1 - 1.2e-50 172.2 31.1 1.4e-50 172.0 31.1 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Spore_YhaL PF14147.6 OAP57026.1 - 0.16 11.7 1.9 0.23 11.1 0.3 2.2 2 0 0 2 2 2 0 Sporulation protein YhaL DUF5504 PF17608.2 OAP57026.1 - 8.8 6.5 13.9 0.47 10.6 5.5 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5504) Sacchrp_dh_C PF16653.5 OAP57027.1 - 1.1e-97 327.3 0.0 1.7e-97 326.7 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 OAP57027.1 - 1.5e-23 83.5 0.2 2.2e-23 83.0 0.2 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 OAP57027.1 - 2.7e-07 30.7 0.1 5.7e-07 29.7 0.1 1.6 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.6 OAP57027.1 - 0.0012 18.7 0.1 0.0058 16.5 0.1 1.9 2 0 0 2 2 2 1 NAD(P)H-binding IlvN PF07991.12 OAP57027.1 - 0.044 13.4 0.1 0.2 11.2 0.0 2.0 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_7 PF13241.6 OAP57027.1 - 0.08 13.4 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Methyltransf_23 PF13489.6 OAP57028.1 - 4.8e-09 36.3 0.0 6.9e-09 35.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAP57028.1 - 0.00089 20.0 0.0 0.0015 19.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAP57028.1 - 0.0031 18.2 0.0 0.04 14.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAP57028.1 - 0.0098 16.5 0.0 0.048 14.3 0.0 2.0 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAP57028.1 - 0.021 14.6 0.0 0.042 13.6 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain CSTF2_hinge PF14327.6 OAP57028.1 - 0.17 12.4 0.1 0.52 10.8 0.1 1.8 1 1 0 1 1 1 0 Hinge domain of cleavage stimulation factor subunit 2 Ribosomal_L28e PF01778.17 OAP57029.1 - 9.7e-36 123.0 0.2 1.9e-35 122.1 0.2 1.5 1 0 0 1 1 1 1 Ribosomal L28e protein family Mak16 PF04874.14 OAP57029.1 - 5.6e-25 87.8 17.6 5.6e-25 87.8 17.6 2.4 1 1 1 2 2 2 1 Mak16 protein C-terminal region BUD22 PF09073.10 OAP57029.1 - 3.5e-05 23.3 15.0 4.4e-05 23.0 15.0 1.0 1 0 0 1 1 1 1 BUD22 TFIIF_alpha PF05793.12 OAP57029.1 - 0.019 13.6 25.1 0.024 13.2 25.1 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PYC_OADA PF02436.18 OAP57029.1 - 0.057 13.2 0.7 0.09 12.5 0.7 1.5 1 0 0 1 1 1 0 Conserved carboxylase domain GDI PF00996.18 OAP57030.1 - 1.7e-29 102.6 0.0 1.2e-28 99.8 0.0 2.2 2 1 0 2 2 2 1 GDP dissociation inhibitor TauD PF02668.16 OAP57031.1 - 1.9e-53 182.0 0.2 2.9e-53 181.4 0.2 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family TPR_11 PF13414.6 OAP57031.1 - 0.031 14.0 0.0 0.078 12.7 0.0 1.6 1 0 0 1 1 1 0 TPR repeat LRR_RI_capping PF18779.1 OAP57031.1 - 0.2 11.4 0.0 0.89 9.3 0.0 1.9 2 0 0 2 2 2 0 Capping Ribonuclease inhibitor Leucine Rich Repeat F-box PF00646.33 OAP57032.1 - 0.0037 17.1 0.0 0.0084 16.0 0.0 1.6 1 0 0 1 1 1 1 F-box domain zf-FPG_IleRS PF06827.14 OAP57032.1 - 0.0083 16.0 1.9 0.0083 16.0 1.9 2.9 3 0 0 3 3 3 1 Zinc finger found in FPG and IleRS F-box PF00646.33 OAP57033.1 - 0.001 18.9 0.2 0.0024 17.7 0.0 1.8 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 OAP57033.1 - 0.033 14.1 0.0 0.059 13.3 0.0 1.4 1 0 0 1 1 1 0 F-box-like DUF4732 PF15876.5 OAP57033.1 - 0.11 12.5 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4732) Zn_clus PF00172.18 OAP57034.1 - 6.6e-09 35.8 6.1 9.8e-09 35.2 6.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3425 PF11905.8 OAP57036.1 - 0.0019 18.1 0.2 0.0045 17.0 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 OAP57036.1 - 0.0024 17.9 0.7 0.0024 17.9 0.7 2.1 2 0 0 2 2 2 1 bZIP transcription factor TRP PF06011.12 OAP57037.1 - 2.2e-120 402.2 17.6 3e-120 401.8 17.6 1.2 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 OAP57037.1 - 2.6e-40 138.0 0.5 4.2e-40 137.3 0.5 1.3 1 0 0 1 1 1 1 ML-like domain VIR_N PF15912.5 OAP57037.1 - 0.2 11.2 6.4 0.34 10.5 6.4 1.3 1 0 0 1 1 1 0 Virilizer, N-terminal DHDPS PF00701.22 OAP57038.1 - 7.3e-37 126.6 0.0 8e-37 126.5 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family His_Phos_2 PF00328.22 OAP57039.1 - 2.1e-40 139.3 0.0 2.5e-40 139.0 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Acetyltransf_1 PF00583.25 OAP57040.1 - 5.7e-11 42.7 0.0 8.1e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OAP57040.1 - 5e-08 33.0 0.0 7.4e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OAP57040.1 - 5.7e-07 29.9 0.1 8.5e-07 29.3 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Cadherin-like PF12733.7 OAP57040.1 - 0.14 12.7 2.0 0.26 11.8 2.0 1.4 1 0 0 1 1 1 0 Cadherin-like beta sandwich domain Cyclin PF08613.11 OAP57041.1 - 4.3e-05 23.9 0.0 4.3e-05 23.9 0.0 2.3 3 0 0 3 3 3 1 Cyclin Cyclin_N PF00134.23 OAP57041.1 - 0.0027 17.4 0.0 0.0063 16.3 0.0 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Pyrid_oxidase_2 PF13883.6 OAP57042.1 - 1.2e-34 119.7 0.0 1.8e-34 119.1 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase HSP9_HSP12 PF04119.12 OAP57043.1 - 3.5e-24 85.0 8.5 3.5e-24 85.0 8.5 3.0 2 1 1 3 3 3 1 Heat shock protein 9/12 YtxH PF12732.7 OAP57043.1 - 0.012 16.1 14.4 0.091 13.3 1.8 3.1 1 1 2 3 3 3 0 YtxH-like protein Apolipoprotein PF01442.18 OAP57043.1 - 0.028 14.3 7.5 0.058 13.3 7.5 1.6 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain ApoLp-III PF07464.11 OAP57043.1 - 0.12 12.5 13.6 0.63 10.1 13.7 2.0 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Tape_meas_lam_C PF09718.10 OAP57043.1 - 0.2 11.8 13.8 0.9 9.7 9.7 2.7 2 1 1 3 3 3 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) DUF883 PF05957.13 OAP57043.1 - 0.25 12.0 8.0 0.97 10.1 3.7 2.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) CRAL_TRIO PF00650.20 OAP57044.1 - 8.1e-14 51.6 0.0 1.3e-13 51.0 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 OAP57044.1 - 0.0031 17.7 0.1 0.0049 17.0 0.1 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.15 OAP57044.1 - 0.018 15.2 0.0 0.042 14.0 0.0 1.7 1 0 0 1 1 1 0 CRAL/TRIO, N-terminal domain LIG3_BRCT PF16759.5 OAP57044.1 - 0.11 12.7 0.0 0.24 11.7 0.0 1.5 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain tRNA-synt_1g PF09334.11 OAP57044.1 - 0.16 10.7 0.0 0.43 9.3 0.0 1.6 2 0 0 2 2 2 0 tRNA synthetases class I (M) GATA PF00320.27 OAP57045.1 - 4.2e-16 58.3 2.5 8.5e-16 57.3 2.5 1.6 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.10 OAP57045.1 - 7.5e-12 44.9 4.1 1.3e-11 44.1 4.1 1.4 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) AreA_N PF07573.11 OAP57045.1 - 0.00074 20.1 2.9 0.00074 20.1 2.9 5.5 6 1 1 7 7 7 1 Nitrogen regulatory protein AreA N terminus Robl_LC7 PF03259.17 OAP57046.1 - 0.0082 15.9 0.0 1.5 8.7 0.0 2.3 2 0 0 2 2 2 2 Roadblock/LC7 domain Ipi1_N PF12333.8 OAP57047.1 - 1.3e-22 80.3 1.4 3.3e-22 79.0 0.0 2.3 2 0 0 2 2 2 1 Rix1 complex component involved in 60S ribosome maturation HEAT_EZ PF13513.6 OAP57047.1 - 0.097 13.2 1.0 1.7 9.3 0.1 2.7 1 1 2 3 3 3 0 HEAT-like repeat Amino_oxidase PF01593.24 OAP57048.1 - 1.7e-49 169.4 0.0 2e-49 169.1 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OAP57048.1 - 1.3e-11 44.5 0.1 2.5e-11 43.6 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 OAP57048.1 - 3.3e-06 26.5 0.1 5e-06 25.9 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 OAP57048.1 - 0.00012 21.6 0.1 0.00017 21.1 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 OAP57048.1 - 0.00042 19.6 0.0 0.00074 18.8 0.0 1.3 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 OAP57048.1 - 0.00081 18.2 0.0 0.0024 16.7 0.0 1.7 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 OAP57048.1 - 0.00098 18.5 0.0 0.06 12.6 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAP57048.1 - 0.0029 17.3 0.0 0.011 15.4 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAP57048.1 - 0.0091 15.3 0.0 0.017 14.4 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OAP57048.1 - 0.019 14.0 0.1 0.4 9.7 0.1 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein GIDA PF01134.22 OAP57048.1 - 0.11 11.6 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A AXE1 PF05448.12 OAP57050.1 - 3.1e-11 42.5 0.0 6.5e-06 25.0 0.0 3.0 3 0 0 3 3 3 2 Acetyl xylan esterase (AXE1) Abhydrolase_6 PF12697.7 OAP57050.1 - 2.3e-07 31.6 0.0 3e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAP57050.1 - 4.4e-06 26.5 0.0 1.1e-05 25.3 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 OAP57050.1 - 1.4e-05 24.8 0.0 1.6e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 OAP57050.1 - 0.0001 21.8 0.0 0.00037 20.0 0.0 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family BAAT_C PF08840.11 OAP57050.1 - 0.00055 19.9 0.0 0.0036 17.2 0.0 2.0 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Hydrolase_4 PF12146.8 OAP57050.1 - 0.0031 16.8 0.0 0.0074 15.6 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 GST_N_3 PF13417.6 OAP57051.1 - 0.00022 21.6 0.1 0.00061 20.2 0.1 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OAP57051.1 - 0.00039 20.7 0.1 0.001 19.3 0.1 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAP57051.1 - 0.024 14.7 0.1 0.26 11.3 0.0 2.6 3 0 0 3 3 3 0 Glutathione S-transferase, C-terminal domain Peptidase_C48 PF02902.19 OAP57052.1 - 5e-23 82.1 0.0 8.9e-23 81.3 0.0 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain PAP2 PF01569.21 OAP57053.1 - 4e-18 65.5 2.0 4e-18 65.5 2.0 1.9 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 OAP57053.1 - 0.0092 15.7 6.1 0.042 13.6 6.1 2.3 1 1 0 1 1 1 1 PAP2 superfamily Ras PF00071.22 OAP57054.1 - 2e-49 167.3 0.0 2.5e-49 167.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAP57054.1 - 1e-20 74.1 0.0 1.7e-20 73.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAP57054.1 - 1e-05 25.1 0.0 2.2e-05 24.0 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family AAA_7 PF12775.7 OAP57054.1 - 0.023 14.2 0.0 0.04 13.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region DASH_Dad1 PF08649.10 OAP57055.1 - 1.7e-22 79.3 0.9 2.2e-22 79.0 0.9 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad1 PilJ PF13675.6 OAP57055.1 - 0.065 13.3 0.1 0.27 11.3 0.1 1.9 1 1 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term LSM PF01423.22 OAP57056.1 - 7.6e-21 73.6 0.1 8.9e-21 73.4 0.1 1.1 1 0 0 1 1 1 1 LSM domain ADH_N_2 PF16884.5 OAP57056.1 - 0.086 12.7 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase DUF866 PF05907.13 OAP57057.1 - 3.2e-63 212.3 0.4 3.5e-63 212.1 0.4 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) HalOD2 PF18547.1 OAP57057.1 - 0.049 13.5 1.7 0.11 12.5 1.7 1.6 1 1 0 1 1 1 0 Halobacterial output domain 2 Zn_ribbon_SprT PF17283.2 OAP57057.1 - 0.11 12.4 2.1 4.6 7.2 0.1 2.3 2 0 0 2 2 2 0 SprT-like zinc ribbon domain Rubredoxin_2 PF18073.1 OAP57057.1 - 0.13 12.0 4.1 2.1 8.2 0.2 2.4 2 0 0 2 2 2 0 Rubredoxin metal binding domain DUF4379 PF14311.6 OAP57057.1 - 0.35 11.3 5.8 0.15 12.5 2.1 2.4 1 1 1 2 2 2 0 Probable Zinc-ribbon domain HET PF06985.11 OAP57058.1 - 4.1e-29 101.8 0.1 7.4e-29 101.0 0.1 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HA2 PF04408.23 OAP57059.1 - 1.4e-14 54.2 0.0 4.8e-14 52.5 0.0 1.9 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 OAP57059.1 - 4.3e-14 52.8 0.1 1.1e-13 51.5 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 OAP57059.1 - 1.5e-11 44.3 0.3 8.2e-11 42.0 0.1 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.16 OAP57059.1 - 0.00057 20.2 0.0 0.0013 19.1 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.6 OAP57059.1 - 0.014 15.6 0.1 0.046 14.0 0.1 1.9 1 0 0 1 1 1 0 AAA domain adh_short_C2 PF13561.6 OAP57060.1 - 1.4e-53 181.9 0.0 6.4e-51 173.2 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP57060.1 - 5.9e-46 156.4 0.1 2.3e-38 131.6 0.0 2.1 1 1 1 2 2 2 2 short chain dehydrogenase KR PF08659.10 OAP57060.1 - 3.8e-05 23.7 0.0 6.8e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 KR domain RF-1 PF00472.20 OAP57061.1 - 1.2e-22 80.0 5.7 2e-22 79.3 5.7 1.3 1 0 0 1 1 1 1 RF-1 domain RabGAP-TBC PF00566.18 OAP57063.1 - 1e-33 116.8 10.6 2.3e-30 105.8 5.2 2.5 2 0 0 2 2 2 2 Rab-GTPase-TBC domain PH_RBD PF12068.8 OAP57063.1 - 1.6e-09 37.4 0.0 3.4e-07 29.9 0.0 3.1 2 1 0 2 2 2 1 Rab-binding domain (RBD) Peptidase_M60 PF13402.6 OAP57063.1 - 0.043 13.3 0.1 0.085 12.4 0.1 1.5 1 0 0 1 1 1 0 Peptidase M60, enhancin and enhancin-like TBCC_N PF16752.5 OAP57063.1 - 0.055 13.9 1.1 0.16 12.5 1.1 1.8 1 0 0 1 1 1 0 Tubulin-specific chaperone C N-terminal domain Rap_GAP PF02145.15 OAP57064.1 - 1.1e-40 139.1 0.0 1.9e-40 138.4 0.0 1.3 1 0 0 1 1 1 1 Rap/ran-GAP DUF3384 PF11864.8 OAP57064.1 - 9.3e-25 87.5 0.0 1.6e-24 86.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3384) Tuberin PF03542.16 OAP57064.1 - 1.1e-24 87.3 3.4 1.7e-21 76.7 0.1 3.6 4 0 0 4 4 4 3 Tuberin CAS_CSE1 PF03378.15 OAP57065.1 - 4.7e-173 575.8 0.0 1.7e-172 573.9 0.0 1.9 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus Cse1 PF08506.10 OAP57065.1 - 2.7e-150 500.3 0.2 3.9e-150 499.8 0.2 1.2 1 0 0 1 1 1 1 Cse1 IBN_N PF03810.19 OAP57065.1 - 1.7e-15 56.7 0.0 8.5e-15 54.4 0.0 2.3 1 0 0 1 1 1 1 Importin-beta N-terminal domain Xpo1 PF08389.12 OAP57065.1 - 0.021 14.9 1.7 0.33 11.0 0.0 3.6 4 1 0 4 4 4 0 Exportin 1-like protein V-ATPase_H_N PF03224.14 OAP57065.1 - 0.11 11.8 0.4 0.82 8.9 0.0 2.5 3 0 0 3 3 3 0 V-ATPase subunit H Phyto_Pns9_10 PF05878.11 OAP57065.1 - 0.11 11.6 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns9/Pns10 Fcf2 PF08698.11 OAP57067.1 - 1.8e-34 118.0 0.5 1.8e-34 118.0 0.5 2.0 2 0 0 2 2 2 1 Fcf2 pre-rRNA processing Mpv17_PMP22 PF04117.12 OAP57069.1 - 9.3e-21 73.8 4.4 1.9e-19 69.6 0.8 2.6 3 0 0 3 3 3 2 Mpv17 / PMP22 family CBFD_NFYB_HMF PF00808.23 OAP57070.1 - 9.6e-19 67.4 0.6 1.3e-18 67.0 0.6 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 OAP57070.1 - 5.6e-16 59.1 0.8 7.7e-16 58.7 0.1 1.5 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.10 OAP57070.1 - 0.061 13.7 0.0 0.097 13.0 0.0 1.3 1 0 0 1 1 1 0 CENP-S associating Centromere protein X Mucin-like PF16058.5 OAP57070.1 - 4.7 7.3 17.4 40 4.4 17.4 2.4 1 1 0 1 1 1 0 Mucin-like Sec15 PF04091.12 OAP57071.1 - 1.5e-101 339.9 0.7 1.5e-101 339.9 0.7 2.5 3 1 0 3 3 3 1 Exocyst complex subunit Sec15-like COG2 PF06148.11 OAP57071.1 - 3.9e-05 23.8 5.5 0.00022 21.3 4.0 2.8 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 AAA_5 PF07728.14 OAP57071.1 - 0.0073 16.3 0.9 0.02 14.9 0.9 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF3510 PF12022.8 OAP57071.1 - 0.064 13.6 3.2 2.7 8.4 0.0 3.8 4 1 1 5 5 5 0 Domain of unknown function (DUF3510) Sec8_exocyst PF04048.14 OAP57071.1 - 0.11 12.4 8.5 0.038 13.9 3.6 2.7 2 1 1 3 3 3 0 Sec8 exocyst complex component specific domain YkyA PF10368.9 OAP57071.1 - 0.82 9.3 6.8 3.1 7.4 6.8 2.0 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein ApoLp-III PF07464.11 OAP57071.1 - 1.1 9.3 7.9 0.34 11.0 4.0 2.2 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) COG5 PF10392.9 OAP57071.1 - 1.2 9.3 13.4 0.022 14.9 4.3 2.8 3 1 0 4 4 4 0 Golgi transport complex subunit 5 RRM_2 PF04059.12 OAP57072.1 - 7.3e-39 131.9 0.2 1.2e-38 131.2 0.2 1.3 1 0 0 1 1 1 1 RNA recognition motif 2 adh_short PF00106.25 OAP57073.1 - 5.4e-35 120.6 0.0 2.6e-26 92.3 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAP57073.1 - 3.7e-22 79.0 0.0 3.3e-15 56.3 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP57073.1 - 9.5e-12 45.2 0.1 1.5e-11 44.5 0.1 1.2 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 OAP57073.1 - 0.0096 16.2 0.1 0.017 15.4 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Polysacc_synt_2 PF02719.15 OAP57073.1 - 0.025 13.7 0.1 0.037 13.2 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein SUI1 PF01253.22 OAP57073.1 - 0.028 14.9 0.1 0.049 14.2 0.1 1.4 1 0 0 1 1 1 0 Translation initiation factor SUI1 DUF5354 PF17305.2 OAP57073.1 - 0.057 13.6 0.0 0.091 13.0 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5354) Cloacin_immun PF03513.14 OAP57073.1 - 0.088 13.2 0.4 0.33 11.3 0.3 1.9 2 0 0 2 2 2 0 Cloacin immunity protein IpaB_EvcA PF03278.13 OAP57073.1 - 0.12 12.1 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 IpaB/EvcA family Asp PF00026.23 OAP57074.1 - 5e-60 203.6 0.3 5.9e-60 203.3 0.3 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OAP57074.1 - 2.9e-11 43.9 6.2 3.6e-08 33.9 2.8 3.8 3 1 0 3 3 3 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 OAP57074.1 - 0.0021 17.9 0.0 0.049 13.4 0.0 2.2 1 1 1 2 2 2 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 OAP57074.1 - 0.0029 18.2 0.5 1.9 9.2 0.0 3.5 2 1 0 2 2 2 1 Aspartyl protease peroxidase PF00141.23 OAP57075.1 - 5.1e-22 78.7 0.0 8.4e-22 78.0 0.0 1.3 1 0 0 1 1 1 1 Peroxidase Pkinase PF00069.25 OAP57077.1 - 7.4e-64 215.7 0.0 8.8e-64 215.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP57077.1 - 1e-29 103.6 0.0 1.4e-29 103.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAP57077.1 - 0.0026 17.1 0.0 0.0074 15.6 0.0 1.7 1 1 0 1 1 1 1 Kinase-like GFA PF04828.14 OAP57078.1 - 3.3e-19 69.0 0.0 4.4e-19 68.6 0.0 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme SNase PF00565.17 OAP57079.1 - 2.6e-82 272.3 0.4 5.7e-25 87.9 0.0 5.5 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.24 OAP57079.1 - 2.6e-26 92.0 0.0 5.2e-26 91.1 0.0 1.5 1 0 0 1 1 1 1 Tudor domain BPL_LplA_LipB PF03099.19 OAP57079.1 - 0.012 15.5 0.0 0.04 13.8 0.0 1.9 1 0 0 1 1 1 0 Biotin/lipoate A/B protein ligase family SMN PF06003.12 OAP57079.1 - 0.014 14.7 0.0 0.029 13.6 0.0 1.5 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Agenet PF05641.12 OAP57079.1 - 0.12 12.9 0.5 0.43 11.1 0.1 2.2 2 0 0 2 2 2 0 Agenet domain Isochorismatase PF00857.20 OAP57080.1 - 1e-17 64.9 0.0 6.7e-07 29.7 0.0 3.2 3 0 0 3 3 3 3 Isochorismatase family DEC-1_N PF04625.13 OAP57081.1 - 0.0061 15.6 7.0 0.0061 15.6 7.0 2.4 2 0 0 2 2 2 1 DEC-1 protein, N-terminal region HDA2-3 PF11496.8 OAP57081.1 - 0.72 9.0 5.2 1.1 8.4 5.0 1.4 1 1 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 Fungal_trans PF04082.18 OAP57082.1 - 4.7e-25 88.1 0.0 1e-24 87.0 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP57082.1 - 1.6e-09 37.7 12.2 2.8e-09 37.0 12.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TIMELESS PF04821.14 OAP57082.1 - 0.15 11.3 0.0 0.26 10.5 0.0 1.2 1 0 0 1 1 1 0 Timeless protein DUF4202 PF13875.6 OAP57085.1 - 3.3e-76 255.4 0.2 3.7e-76 255.2 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4202) Amidohydro_2 PF04909.14 OAP57086.1 - 6e-36 124.7 0.2 6.8e-36 124.5 0.2 1.0 1 0 0 1 1 1 1 Amidohydrolase TatD_DNase PF01026.21 OAP57086.1 - 0.01 15.2 0.0 0.016 14.6 0.0 1.4 1 0 0 1 1 1 0 TatD related DNase rRNA_methylase PF06962.12 OAP57086.1 - 0.18 11.8 0.0 0.33 10.9 0.0 1.3 1 0 0 1 1 1 0 Putative rRNA methylase SNF5 PF04855.12 OAP57088.1 - 1.3e-84 283.7 0.0 2.8e-84 282.6 0.0 1.5 2 0 0 2 2 2 1 SNF5 / SMARCB1 / INI1 GATA PF00320.27 OAP57088.1 - 0.00027 20.5 1.2 0.00027 20.5 1.2 1.8 2 0 0 2 2 2 1 GATA zinc finger WD40 PF00400.32 OAP57089.1 - 1.7e-21 76.1 18.9 0.00029 21.6 0.7 7.1 6 2 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAP57089.1 - 3.7e-09 36.8 5.3 0.0085 16.4 0.0 4.7 3 2 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain TFIIIC_delta PF12657.7 OAP57089.1 - 0.0013 18.7 6.4 0.0082 16.1 0.2 2.6 2 1 1 3 3 3 2 Transcription factor IIIC subunit delta N-term Ge1_WD40 PF16529.5 OAP57089.1 - 0.13 11.3 5.1 2.4 7.0 0.0 3.8 2 2 2 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein tRNA-synt_1c PF00749.21 OAP57090.1 - 2.7e-87 292.6 0.0 6e-87 291.5 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain DnaJ_C PF01556.18 OAP57091.1 - 8e-38 129.8 0.4 1.4e-37 129.0 0.4 1.4 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 OAP57091.1 - 7.7e-22 77.2 2.3 1.4e-21 76.3 2.3 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 OAP57091.1 - 1.5e-13 50.9 20.0 2.7e-13 50.0 20.0 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 OAP57091.1 - 0.021 14.8 18.5 0.21 11.6 5.9 2.6 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 OAP57091.1 - 0.034 14.2 8.5 0.56 10.2 1.2 2.4 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF1356 PF07092.12 OAP57091.1 - 0.098 11.9 5.6 0.35 10.1 0.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1356) TackOD1 PF18551.1 OAP57091.1 - 0.75 9.4 8.0 1.3 8.6 0.7 2.2 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 zf-RING_10 PF16685.5 OAP57091.1 - 1.1 9.4 6.2 3.5 7.8 0.5 2.3 2 0 0 2 2 2 0 zinc RING finger of MSL2 DAO PF01266.24 OAP57092.1 - 1.6e-54 185.9 0.0 1.8e-54 185.7 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 OAP57092.1 - 3.3e-07 29.8 0.0 7.1e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 OAP57092.1 - 2e-05 24.7 0.2 6.9e-05 23.0 0.2 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 OAP57092.1 - 0.00074 18.9 0.0 0.032 13.5 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAP57092.1 - 0.00075 19.5 0.1 0.0058 16.6 0.0 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 OAP57092.1 - 0.0012 18.0 0.0 0.0016 17.5 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 OAP57092.1 - 0.0052 16.0 0.5 0.082 12.1 0.5 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAP57092.1 - 0.0062 15.7 0.1 0.013 14.6 0.0 1.5 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Mqo PF06039.15 OAP57092.1 - 0.029 12.9 0.1 0.19 10.3 0.0 2.0 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) FAD_binding_2 PF00890.24 OAP57092.1 - 0.033 13.3 0.3 0.12 11.4 0.2 1.8 2 0 0 2 2 2 0 FAD binding domain 3HCDH_N PF02737.18 OAP57092.1 - 0.046 13.6 0.1 0.091 12.6 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.14 OAP57092.1 - 0.11 11.2 0.4 4.4 5.9 0.3 2.1 2 0 0 2 2 2 0 HI0933-like protein Rox3 PF08633.10 OAP57093.1 - 4e-55 187.3 1.1 6.4e-55 186.6 1.1 1.3 1 0 0 1 1 1 1 Rox3 mediator complex subunit HAD_2 PF13419.6 OAP57094.1 - 0.00052 20.1 0.0 0.00086 19.4 0.0 1.3 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OAP57094.1 - 0.0083 16.4 0.0 0.013 15.8 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Amidase PF01425.21 OAP57096.1 - 1e-90 304.9 0.0 2.8e-90 303.4 0.0 1.6 1 1 0 1 1 1 1 Amidase NmrA PF05368.13 OAP57097.1 - 2.5e-10 40.3 0.0 1.6e-09 37.7 0.0 1.9 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAP57097.1 - 9.6e-06 25.6 0.0 1.5e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding KRAB PF01352.27 OAP57098.1 - 0.021 14.5 0.0 0.04 13.6 0.0 1.5 1 0 0 1 1 1 0 KRAB box ADH_zinc_N PF00107.26 OAP57099.1 - 2.3e-19 69.7 0.0 3.3e-19 69.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 OAP57099.1 - 3.2e-18 65.6 0.0 4.9e-18 65.0 0.0 1.3 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 OAP57099.1 - 2.2e-07 32.0 0.0 3.7e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Aldedh PF00171.22 OAP57100.1 - 1.2e-131 439.4 0.1 1.4e-131 439.3 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family baeRF_family2 PF18844.1 OAP57100.1 - 0.094 12.8 0.2 0.26 11.3 0.2 1.7 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 2 MCM PF00493.23 OAP57101.1 - 3.7e-101 336.9 0.1 6.6e-101 336.1 0.1 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 OAP57101.1 - 5.4e-37 126.4 0.7 1.2e-36 125.4 0.7 1.5 1 0 0 1 1 1 1 MCM OB domain MCM6_C PF18263.1 OAP57101.1 - 8.8e-29 99.9 0.1 2.2e-28 98.6 0.0 1.8 2 0 0 2 2 2 1 MCM6 C-terminal winged-helix domain MCM_lid PF17855.1 OAP57101.1 - 1.2e-23 83.4 0.2 2.9e-23 82.1 0.2 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 OAP57101.1 - 6.2e-21 74.9 0.0 1.6e-20 73.6 0.0 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 OAP57101.1 - 3.8e-06 26.4 0.0 3.6e-05 23.3 0.0 2.2 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 OAP57101.1 - 0.0039 17.2 0.0 0.0096 15.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 OAP57101.1 - 0.0049 16.6 0.0 0.0098 15.6 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.11 OAP57101.1 - 0.018 14.9 0.0 0.053 13.4 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SR1P PF13790.6 OAP57101.1 - 0.24 11.6 3.2 1.1 9.4 0.3 2.4 2 0 0 2 2 2 0 SR1 protein zf-C3H1 PF10650.9 OAP57102.1 - 1.5e-08 34.2 1.6 2.5e-08 33.5 1.6 1.4 1 0 0 1 1 1 1 Putative zinc-finger domain XhlA PF10779.9 OAP57102.1 - 5.3 7.3 4.9 2.8 8.2 0.6 2.5 2 0 0 2 2 2 0 Haemolysin XhlA Myosin_head PF00063.21 OAP57103.1 - 4.8e-264 877.7 0.0 8.3e-264 876.9 0.0 1.4 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_N PF02736.19 OAP57103.1 - 1.8e-10 40.5 0.1 3.9e-10 39.4 0.1 1.6 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain GAS PF13851.6 OAP57103.1 - 0.0059 16.0 24.1 0.0059 16.0 24.1 5.8 1 1 5 6 6 6 5 Growth-arrest specific micro-tubule binding Fib_alpha PF08702.10 OAP57103.1 - 0.0075 16.5 14.0 0.0075 16.5 14.0 4.7 1 1 3 5 5 5 2 Fibrinogen alpha/beta chain family AAA_19 PF13245.6 OAP57103.1 - 0.074 13.4 0.0 0.3 11.4 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 OAP57103.1 - 0.11 12.8 0.0 0.11 12.8 0.0 4.6 3 1 0 3 3 3 0 AAA ATPase domain AAA_22 PF13401.6 OAP57103.1 - 0.13 12.5 0.0 0.13 12.5 0.0 4.1 4 1 1 5 5 5 0 AAA domain LtuB PF17455.2 OAP57103.1 - 3.1 8.5 4.9 5.3 7.7 0.9 3.2 2 0 0 2 2 2 0 Late transcription unit B NPV_P10 PF05531.12 OAP57103.1 - 6.6 7.3 22.3 5.7 7.5 2.6 5.4 2 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein MFS_1 PF07690.16 OAP57104.1 - 1.9e-08 33.7 37.2 3.8e-08 32.6 36.5 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 OAP57104.1 - 2.7e-08 33.7 5.4 2.7e-08 33.7 5.4 2.3 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 EXS PF03124.14 OAP57104.1 - 0.0013 18.2 3.2 0.003 16.9 3.2 1.8 1 0 0 1 1 1 1 EXS family LapA_dom PF06305.11 OAP57104.1 - 0.39 10.6 0.0 0.39 10.6 0.0 3.1 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain BcrAD_BadFG PF01869.20 OAP57105.1 - 1.1e-17 64.5 1.0 1.9e-17 63.6 1.0 1.4 1 0 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family SIS_2 PF13580.6 OAP57105.1 - 0.00043 20.3 4.1 0.0015 18.6 0.2 3.5 3 1 0 3 3 3 1 SIS domain SIS PF01380.22 OAP57105.1 - 0.021 14.7 1.1 0.068 13.0 0.0 2.4 2 0 0 2 2 2 0 SIS domain DDOST_48kD PF03345.14 OAP57106.1 - 2.8e-158 527.1 0.0 3.2e-158 526.9 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta BTB PF00651.31 OAP57108.1 - 0.03 14.5 0.0 0.076 13.2 0.0 1.6 1 0 0 1 1 1 0 BTB/POZ domain GST_N_3 PF13417.6 OAP57110.1 - 5e-13 49.3 0.0 1.1e-12 48.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OAP57110.1 - 5.7e-07 29.7 0.0 1.2e-06 28.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAP57110.1 - 8.6e-07 28.9 0.1 1.5e-06 28.1 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OAP57110.1 - 2.3e-06 27.7 0.0 3.6e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OAP57110.1 - 0.00032 20.8 0.0 0.00052 20.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 OAP57110.1 - 0.0017 18.7 0.0 0.012 15.9 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain DUF104 PF01954.16 OAP57110.1 - 0.14 12.7 0.3 3.5 8.1 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function DUF104 Aldedh PF00171.22 OAP57113.1 - 2.2e-43 148.4 0.0 8.1e-32 110.3 0.0 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family DUF1487 PF07368.11 OAP57113.1 - 0.024 14.1 0.0 0.032 13.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1487) FAD_binding_3 PF01494.19 OAP57114.1 - 1e-13 51.3 1.7 3.3e-07 29.9 0.0 3.1 2 1 1 3 3 3 2 FAD binding domain Pyr_redox_2 PF07992.14 OAP57114.1 - 3.9e-08 32.9 0.0 2.2e-05 23.8 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAP57114.1 - 5.3e-08 32.8 3.1 4.3e-06 26.6 1.9 2.3 1 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OAP57114.1 - 5.8e-06 25.6 0.2 1e-05 24.9 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 OAP57114.1 - 1.1e-05 25.5 1.3 4.1e-05 23.7 1.3 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 OAP57114.1 - 0.00018 20.3 0.3 0.012 14.4 0.3 2.1 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 OAP57114.1 - 0.0035 16.5 0.1 0.0081 15.3 0.1 1.5 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox PF00070.27 OAP57114.1 - 0.0062 17.1 0.5 0.067 13.8 0.9 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAP57114.1 - 0.02 14.2 0.0 0.17 11.1 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OAP57114.1 - 0.02 13.9 0.0 1.5 7.7 0.1 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein Amino_oxidase PF01593.24 OAP57114.1 - 0.037 13.3 0.2 0.94 8.7 0.1 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Thi4 PF01946.17 OAP57114.1 - 0.11 11.8 0.3 0.2 10.9 0.3 1.4 1 0 0 1 1 1 0 Thi4 family NAD_binding_7 PF13241.6 OAP57114.1 - 0.19 12.2 0.0 0.33 11.4 0.0 1.6 1 1 0 1 1 1 0 Putative NAD(P)-binding NAD_binding_9 PF13454.6 OAP57114.1 - 0.2 11.6 1.3 30 4.6 0.0 2.9 3 0 0 3 3 3 0 FAD-NAD(P)-binding Trp_halogenase PF04820.14 OAP57114.1 - 0.3 9.9 1.1 1.8 7.3 0.8 2.0 2 0 0 2 2 2 0 Tryptophan halogenase FAD_oxidored PF12831.7 OAP57114.1 - 0.83 8.9 5.1 0.31 10.3 2.0 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase CHAT PF12770.7 OAP57115.1 - 8.8e-33 113.9 0.4 1.1e-32 113.6 0.4 1.1 1 0 0 1 1 1 1 CHAT domain Aminotran_3 PF00202.21 OAP57116.1 - 3.1e-84 283.0 0.0 4e-84 282.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III NUMOD1 PF07453.13 OAP57116.1 - 0.14 12.5 0.0 0.51 10.7 0.0 2.0 2 0 0 2 2 2 0 NUMOD1 domain AA_permease PF00324.21 OAP57117.1 - 2.2e-123 412.4 37.8 2.7e-123 412.1 37.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAP57117.1 - 2.7e-35 122.0 40.3 3.3e-35 121.8 40.3 1.1 1 0 0 1 1 1 1 Amino acid permease Fungal_trans PF04082.18 OAP57118.1 - 3e-13 49.4 0.1 1e-12 47.7 0.1 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain SOR_SNZ PF01680.17 OAP57119.1 - 9.6e-107 355.4 6.9 1.3e-106 354.9 6.9 1.2 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.14 OAP57119.1 - 4.5e-08 32.7 8.9 7.1e-06 25.5 1.6 2.6 2 2 0 2 2 2 2 Thiazole biosynthesis protein ThiG Dus PF01207.17 OAP57119.1 - 2e-05 23.9 0.3 0.1 11.7 0.1 2.6 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 OAP57119.1 - 8.5e-05 22.1 0.8 0.024 14.1 0.1 2.8 2 1 0 2 2 2 2 Histidine biosynthesis protein NanE PF04131.14 OAP57119.1 - 0.0016 17.7 1.0 0.057 12.6 0.0 2.8 1 1 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase IGPS PF00218.21 OAP57119.1 - 0.0081 15.4 0.2 0.37 9.9 0.0 2.5 2 1 0 2 2 2 1 Indole-3-glycerol phosphate synthase Ribosomal_L29 PF00831.23 OAP57119.1 - 0.011 15.7 0.2 0.072 13.1 0.1 2.1 2 0 0 2 2 2 0 Ribosomal L29 protein TetR_C_27 PF17935.1 OAP57119.1 - 0.014 15.4 0.0 0.036 14.1 0.0 1.6 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain NMO PF03060.15 OAP57119.1 - 0.062 12.7 9.6 0.1 12.0 3.2 2.2 2 0 0 2 2 2 0 Nitronate monooxygenase MmgE_PrpD PF03972.14 OAP57120.1 - 2.6e-99 332.7 2.9 3.2e-99 332.5 2.9 1.0 1 0 0 1 1 1 1 MmgE/PrpD family Methyltransf_2 PF00891.18 OAP57121.1 - 9e-25 87.2 0.0 1.4e-24 86.5 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain AA_permease PF00324.21 OAP57122.1 - 2.4e-134 448.5 36.8 3e-134 448.2 36.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAP57122.1 - 4.7e-39 134.4 37.6 6.2e-39 134.0 37.6 1.0 1 0 0 1 1 1 1 Amino acid permease Asp PF00026.23 OAP57123.1 - 1.5e-35 123.2 0.2 3.3e-34 118.7 0.2 2.2 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OAP57123.1 - 0.0027 18.0 1.7 0.072 13.3 0.5 3.2 3 1 0 3 3 3 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 OAP57123.1 - 0.016 15.0 0.2 0.13 12.0 0.0 2.3 3 0 0 3 3 3 0 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 OAP57123.1 - 0.057 14.1 0.7 25 5.6 0.0 4.1 5 1 0 5 5 5 0 Aspartyl protease gag-asp_proteas PF13975.6 OAP57123.1 - 0.18 12.3 0.9 30 5.3 0.1 3.6 5 0 0 5 5 5 0 gag-polyprotein putative aspartyl protease p450 PF00067.22 OAP57125.1 - 1.9e-72 244.5 0.0 2.6e-72 244.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.20 OAP57125.1 - 6.9e-30 104.3 0.0 1.2e-29 103.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 OAP57125.1 - 2.6e-20 73.1 0.0 5.6e-20 72.0 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 OAP57125.1 - 2.2e-14 54.0 0.0 1.4e-13 51.4 0.0 2.5 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 OAP57125.1 - 0.00057 20.1 0.0 0.0014 18.8 0.0 1.7 1 0 0 1 1 1 1 Flavodoxin domain Glyco_tranf_2_2 PF10111.9 OAP57125.1 - 0.15 11.5 0.0 0.29 10.6 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase like family 2 ABC2_membrane PF01061.24 OAP57126.1 - 2.7e-71 239.3 63.7 6.2e-39 133.6 20.3 3.0 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 OAP57126.1 - 8.8e-38 129.9 0.0 2.8e-19 70.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 OAP57126.1 - 1.3e-25 89.1 7.5 7.6e-23 80.2 0.1 3.5 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.6 OAP57126.1 - 5.5e-15 55.7 0.0 1.6e-14 54.2 0.0 1.9 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 OAP57126.1 - 1.5e-07 31.9 0.9 0.00059 20.3 0.1 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 OAP57126.1 - 3.6e-05 23.7 2.4 0.025 14.4 0.1 2.8 2 1 1 3 3 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 OAP57126.1 - 0.00012 21.7 1.0 0.0049 16.5 0.1 2.7 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.6 OAP57126.1 - 0.00013 22.1 0.3 0.15 12.2 0.1 2.6 2 0 0 2 2 2 2 AAA domain ABC2_membrane_3 PF12698.7 OAP57126.1 - 0.0002 20.6 18.8 0.0002 20.6 18.8 2.9 3 1 0 3 3 1 1 ABC-2 family transporter protein RsgA_GTPase PF03193.16 OAP57126.1 - 0.00027 20.9 2.0 0.00027 20.9 0.2 1.8 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 OAP57126.1 - 0.00045 20.5 0.2 0.047 14.0 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.6 OAP57126.1 - 0.00095 18.9 1.0 0.047 13.4 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_30 PF13604.6 OAP57126.1 - 0.0017 18.1 0.1 0.12 12.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 OAP57126.1 - 0.002 18.7 0.0 0.071 13.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 OAP57126.1 - 0.019 15.4 0.3 6.8 7.1 0.2 3.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) SMC_N PF02463.19 OAP57126.1 - 0.034 13.6 0.1 1.4 8.3 0.0 2.9 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain T2SSE PF00437.20 OAP57126.1 - 0.057 12.5 0.2 2.5 7.1 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein NACHT PF05729.12 OAP57126.1 - 0.075 12.9 5.7 0.98 9.3 0.3 3.1 3 0 0 3 3 2 0 NACHT domain FeoB_N PF02421.18 OAP57126.1 - 0.1 12.1 0.2 0.53 9.8 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B MMR_HSR1 PF01926.23 OAP57126.1 - 0.11 12.6 0.9 2.2 8.4 0.1 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase Zeta_toxin PF06414.12 OAP57126.1 - 0.11 11.7 0.0 0.49 9.7 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin AAA_23 PF13476.6 OAP57126.1 - 0.12 12.9 0.1 1.1 9.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 OAP57126.1 - 0.13 12.5 0.2 3.9 7.8 0.0 3.0 3 0 0 3 3 3 0 Putative exonuclease SbcCD, C subunit AAA_24 PF13479.6 OAP57126.1 - 0.21 11.3 0.6 2.2 7.9 0.1 2.2 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 OAP57126.1 - 0.22 11.5 0.9 2.7 8.0 0.2 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE cobW PF02492.19 OAP57126.1 - 0.98 9.0 4.4 0.53 9.9 0.5 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Protoglobin PF11563.8 OAP57128.1 - 8.3e-37 126.5 0.1 1e-36 126.2 0.1 1.1 1 0 0 1 1 1 1 Protoglobin Ribosomal_L37 PF08561.10 OAP57129.1 - 1.8e-37 128.5 1.8 2.8e-37 127.9 1.8 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L37 RRM_1 PF00076.22 OAP57131.1 - 1.4e-40 136.9 0.0 4.2e-19 68.1 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OAP57131.1 - 8.1e-06 25.9 0.0 0.18 12.0 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif Alg6_Alg8 PF03155.15 OAP57132.1 - 2.8e-130 435.5 23.7 8.5e-82 275.7 11.2 2.2 2 0 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family Fasciclin PF02469.22 OAP57133.1 - 0.00039 20.6 0.0 0.00055 20.1 0.0 1.3 1 0 0 1 1 1 1 Fasciclin domain ADH_zinc_N PF00107.26 OAP57136.1 - 9.9e-26 90.2 0.0 1.6e-25 89.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAP57136.1 - 4.8e-22 77.9 0.3 8.1e-22 77.2 0.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 OAP57136.1 - 9.6e-08 33.2 0.0 1.3e-07 32.7 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 OAP57136.1 - 5.1e-05 22.7 0.2 9.3e-05 21.8 0.2 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Methyltransf_25 PF13649.6 OAP57136.1 - 0.0012 19.5 0.1 0.0025 18.5 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAP57136.1 - 0.0054 17.3 0.2 0.023 15.3 0.2 2.1 1 1 0 1 1 1 1 Methyltransferase domain BKACE PF05853.12 OAP57136.1 - 0.0055 16.1 0.0 0.007 15.7 0.0 1.3 1 0 0 1 1 1 1 beta-keto acid cleavage enzyme 2-Hacid_dh_C PF02826.19 OAP57136.1 - 0.0068 15.8 0.1 0.013 14.8 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 OAP57136.1 - 0.012 15.9 0.4 0.02 15.2 0.4 1.3 1 0 0 1 1 1 0 TrkA-N domain Methyltransf_31 PF13847.6 OAP57136.1 - 0.023 14.5 0.2 0.13 12.1 0.1 2.0 1 1 0 1 1 1 0 Methyltransferase domain CMAS PF02353.20 OAP57136.1 - 0.024 13.9 0.3 0.038 13.3 0.3 1.5 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase ApbA PF02558.16 OAP57136.1 - 0.068 12.8 0.3 0.12 12.0 0.1 1.5 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Methyltransf_12 PF08242.12 OAP57136.1 - 0.096 13.4 0.0 0.19 12.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 OAP57136.1 - 0.13 11.6 0.2 1 8.6 0.2 2.1 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family AMP-binding PF00501.28 OAP57137.1 - 9.3e-58 195.8 0.0 1.4e-57 195.2 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 OAP57137.1 - 7.8e-28 97.3 0.0 1.3e-27 96.6 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 OAP57137.1 - 4.9e-10 39.3 0.0 8.4e-10 38.5 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 OAP57137.1 - 1.5e-06 28.4 0.2 4.4e-06 26.9 0.2 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.19 OAP57137.1 - 0.00061 18.9 0.0 0.19 10.7 0.0 2.3 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding_C PF13193.6 OAP57137.1 - 0.0009 20.2 0.0 0.0071 17.3 0.1 2.6 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain Peptidase_C9 PF01707.16 OAP57137.1 - 0.098 12.2 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Peptidase family C9 Fungal_trans PF04082.18 OAP57138.1 - 1.1e-21 77.1 0.3 1.7e-21 76.5 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP57138.1 - 1.8e-05 24.8 8.7 1.8e-05 24.8 8.7 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FMO-like PF00743.19 OAP57139.1 - 9.1e-21 73.9 0.1 2.7e-19 69.0 0.0 2.2 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 OAP57139.1 - 5.6e-14 52.0 0.0 5.3e-13 48.8 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 OAP57139.1 - 3.1e-13 49.6 0.0 1.9e-10 40.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAP57139.1 - 8.9e-10 38.3 0.0 5.1e-08 32.5 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAP57139.1 - 1.1e-08 35.2 0.0 8.8e-05 22.7 0.0 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 OAP57139.1 - 4.9e-05 23.4 0.2 0.076 13.0 0.1 3.5 3 1 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.24 OAP57139.1 - 0.0033 17.0 0.4 0.1 12.2 0.1 2.6 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 OAP57139.1 - 0.004 17.7 0.0 0.021 15.4 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 OAP57139.1 - 0.014 15.9 0.2 0.26 11.8 0.1 2.8 2 1 0 2 2 2 0 Putative NAD(P)-binding Shikimate_DH PF01488.20 OAP57139.1 - 0.019 15.0 0.0 0.04 14.0 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.14 OAP57139.1 - 0.029 13.1 0.6 4.5 5.9 0.0 2.6 3 0 0 3 3 3 0 HI0933-like protein F420_oxidored PF03807.17 OAP57139.1 - 0.034 14.7 0.0 0.094 13.3 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 OAP57139.1 - 0.067 12.5 0.1 0.18 11.1 0.0 1.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Aldo_ket_red PF00248.21 OAP57141.1 - 2.7e-64 217.2 0.0 3.9e-64 216.7 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family Fungal_trans PF04082.18 OAP57141.1 - 0.0044 16.1 0.0 0.0082 15.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short_C2 PF13561.6 OAP57143.1 - 5.6e-49 166.8 0.0 7.1e-49 166.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP57143.1 - 1.6e-32 112.6 0.0 2.1e-32 112.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAP57143.1 - 2.4e-07 30.9 0.0 4.9e-07 29.8 0.0 1.5 1 1 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 OAP57143.1 - 0.038 13.1 0.1 0.089 11.9 0.0 1.5 2 0 0 2 2 2 0 RmlD substrate binding domain Epimerase PF01370.21 OAP57143.1 - 0.092 12.2 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family SHD1 PF03983.12 OAP57144.1 - 9.9e-33 111.8 0.0 1.8e-32 110.9 0.0 1.4 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_1 PF00018.28 OAP57144.1 - 2.1e-32 110.5 11.7 2.8e-13 49.2 0.2 4.4 4 0 0 4 4 4 3 SH3 domain SH3_9 PF14604.6 OAP57144.1 - 1.2e-26 92.3 9.9 6e-10 38.8 0.3 3.6 3 0 0 3 3 3 3 Variant SH3 domain SH3_2 PF07653.17 OAP57144.1 - 6e-18 64.3 0.1 2e-05 24.1 0.0 4.4 4 0 0 4 4 4 4 Variant SH3 domain DUF1720 PF08226.11 OAP57144.1 - 5.5e-08 33.1 110.1 1e-06 29.0 35.9 6.8 2 1 4 6 6 6 5 Domain of unknown function (DUF1720) SH3_10 PF17902.1 OAP57144.1 - 0.00099 19.1 0.0 0.11 12.5 0.0 3.1 3 0 0 3 3 3 1 SH3 domain SAM_4 PF18017.1 OAP57144.1 - 0.018 15.0 0.0 0.036 14.0 0.0 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) SH3_3 PF08239.11 OAP57144.1 - 0.037 14.3 8.7 0.12 12.7 1.0 3.2 3 0 0 3 3 3 0 Bacterial SH3 domain PRKCSH PF07915.13 OAP57145.1 - 3.5e-19 69.6 1.9 3.9e-19 69.4 0.2 2.0 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.6 OAP57145.1 - 0.071 12.8 0.1 0.17 11.5 0.0 1.7 2 0 0 2 2 2 0 Glucosidase II beta subunit-like protein TFIIA PF03153.13 OAP57145.1 - 1.3 8.9 7.3 1.6 8.6 6.3 1.4 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit LRR_6 PF13516.6 OAP57146.1 - 3e-17 61.1 6.2 0.022 14.8 0.0 7.6 8 0 0 8 8 8 5 Leucine Rich repeat LRR_4 PF12799.7 OAP57146.1 - 7.8e-05 23.0 18.1 0.83 10.2 0.5 6.4 5 3 2 8 8 8 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OAP57146.1 - 0.00082 19.6 2.2 1.9e+02 3.3 0.0 6.3 7 1 0 7 7 7 0 Leucine Rich Repeat LRR_8 PF13855.6 OAP57146.1 - 0.0017 18.1 10.5 8 6.3 0.0 5.9 5 2 0 5 5 5 2 Leucine rich repeat Drc1-Sld2 PF11719.8 OAP57146.1 - 1.7 8.1 8.5 2.3 7.7 8.5 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein EMC3_TMCO1 PF01956.16 OAP57147.1 - 1.5e-54 184.3 0.2 2e-54 183.9 0.2 1.2 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like zf-C4_Topoisom PF01396.19 OAP57148.1 - 0.035 13.9 0.2 0.13 12.1 0.0 2.0 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger NDUFA12 PF05071.16 OAP57149.1 - 2.1e-09 38.1 0.6 2.1e-09 38.1 0.6 1.7 2 0 0 2 2 2 1 NADH ubiquinone oxidoreductase subunit NDUFA12 CH PF00307.31 OAP57150.1 - 1.5e-14 54.0 0.0 3.3e-14 53.0 0.0 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain DUF3247 PF11607.8 OAP57151.1 - 0.13 12.6 0.0 1.6 9.0 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3247) FAD_binding_3 PF01494.19 OAP57152.1 - 2.9e-18 66.2 0.1 8.3e-18 64.7 0.1 1.8 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAP57152.1 - 5.2e-07 29.6 0.2 1.5e-06 28.1 0.1 1.8 1 1 1 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAP57152.1 - 3.3e-05 24.0 0.0 8.8e-05 22.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAP57152.1 - 0.00027 20.3 0.2 0.0043 16.3 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAP57152.1 - 0.0098 15.0 0.9 0.015 14.4 0.4 1.5 2 0 0 2 2 2 1 FAD binding domain CD34_antigen PF06365.12 OAP57152.1 - 0.011 15.4 0.0 0.021 14.4 0.0 1.4 1 0 0 1 1 1 0 CD34/Podocalyxin family SE PF08491.10 OAP57152.1 - 0.013 14.6 0.0 0.1 11.6 0.0 2.0 2 0 0 2 2 2 0 Squalene epoxidase NAD_binding_9 PF13454.6 OAP57152.1 - 0.015 15.3 0.2 0.55 10.2 0.2 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Trp_halogenase PF04820.14 OAP57152.1 - 0.017 14.0 2.2 0.076 11.8 0.4 2.1 2 0 0 2 2 2 0 Tryptophan halogenase HI0933_like PF03486.14 OAP57152.1 - 0.02 13.6 0.1 0.03 13.0 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.27 OAP57152.1 - 0.071 13.7 0.2 0.18 12.4 0.2 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 OAP57152.1 - 0.13 12.2 0.1 0.21 11.5 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.22 OAP57152.1 - 0.17 10.9 0.3 0.28 10.2 0.3 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A ADH_N PF08240.12 OAP57153.1 - 1.7e-21 76.1 0.3 2.7e-21 75.5 0.3 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAP57153.1 - 5.7e-14 52.2 0.0 9.4e-14 51.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 OAP57153.1 - 8.7e-05 22.1 0.0 0.00016 21.3 0.0 1.4 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 OAP57153.1 - 0.00015 22.8 0.0 0.00027 22.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 OAP57153.1 - 0.0015 18.4 0.1 0.005 16.7 0.0 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-associated DAO PF01266.24 OAP57153.1 - 0.15 11.6 2.1 7.1 6.1 2.6 2.2 1 1 0 2 2 2 0 FAD dependent oxidoreductase MatE PF01554.18 OAP57154.1 - 9.1e-09 35.2 12.3 0.00014 21.6 1.9 3.5 3 0 0 3 3 3 3 MatE Polysacc_synt_C PF14667.6 OAP57154.1 - 0.0018 18.3 0.6 0.0018 18.3 0.6 3.1 4 1 0 4 4 4 1 Polysaccharide biosynthesis C-terminal domain Aminotran_1_2 PF00155.21 OAP57155.1 - 1.3e-46 159.5 0.0 1.6e-46 159.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Nbl1_Borealin_N PF10444.9 OAP57156.1 - 3.5e-20 71.4 5.5 5.8e-20 70.7 5.5 1.4 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal DUF3546 PF12066.8 OAP57157.1 - 7.4e-33 113.0 4.6 7.4e-33 113.0 4.6 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF3546) DUF4187 PF13821.6 OAP57157.1 - 1.7e-12 46.9 0.2 4.2e-12 45.7 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) ARS2 PF04959.13 OAP57157.1 - 2.1e-10 41.3 0.6 2.1e-10 41.3 0.6 2.6 2 1 1 3 3 3 1 Arsenite-resistance protein 2 SPT6_acidic PF14632.6 OAP57158.1 - 0.016 15.7 0.3 6.8 7.3 1.0 2.2 1 1 1 2 2 2 0 Acidic N-terminal SPT6 TspO_MBR PF03073.15 OAP57159.1 - 3e-45 153.6 4.2 4.8e-45 152.9 4.2 1.4 1 1 0 1 1 1 1 TspO/MBR family Corona_NS3b PF03053.14 OAP57159.1 - 0.2 11.4 0.3 0.27 11.0 0.3 1.1 1 0 0 1 1 1 0 ORF3b coronavirus protein Zip PF02535.22 OAP57160.1 - 6.3e-51 173.6 1.5 7.6e-51 173.3 1.5 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Abhydrolase_6 PF12697.7 OAP57161.1 - 2.7e-12 47.8 5.5 1.1e-10 42.5 5.5 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAP57161.1 - 1e-07 31.9 0.0 1.8e-07 31.0 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAP57161.1 - 0.003 16.8 0.0 0.77 9.0 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Scytalone_dh PF02982.14 OAP57162.1 - 3.8e-83 277.0 2.1 5e-83 276.7 2.1 1.1 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.6 OAP57162.1 - 6.1e-07 29.6 1.1 9.2e-07 29.0 1.1 1.3 1 0 0 1 1 1 1 SnoaL-like domain Vint PF14623.6 OAP57163.1 - 1.2e-54 184.6 0.0 1.9e-54 183.9 0.0 1.3 1 0 0 1 1 1 1 Hint-domain Vwaint PF14624.6 OAP57163.1 - 2.1e-22 79.0 0.0 4.6e-22 77.9 0.0 1.5 1 0 0 1 1 1 1 VWA / Hh protein intein-like VWA_2 PF13519.6 OAP57163.1 - 2.7e-12 47.3 0.0 9.1e-12 45.6 0.0 2.0 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.28 OAP57163.1 - 6e-12 46.2 0.0 1.2e-11 45.2 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 OAP57163.1 - 3.7e-06 27.0 0.1 0.00051 20.0 0.0 3.3 2 1 0 2 2 2 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 OAP57163.1 - 0.14 11.5 0.1 0.33 10.3 0.1 1.6 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein Peptidase_C1_2 PF03051.15 OAP57163.1 - 0.28 9.9 0.0 0.41 9.4 0.0 1.1 1 0 0 1 1 1 0 Peptidase C1-like family Epimerase PF01370.21 OAP57164.1 - 2e-13 50.4 0.0 3.9e-13 49.4 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OAP57164.1 - 7.5e-10 38.3 0.0 1.6e-09 37.2 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 OAP57164.1 - 7.2e-07 28.9 0.0 1.3e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 OAP57164.1 - 2.9e-06 27.3 0.0 1.4e-05 25.1 0.0 2.0 1 1 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 OAP57164.1 - 0.00011 21.9 0.1 0.00017 21.3 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.25 OAP57164.1 - 0.00048 19.6 0.4 0.0037 16.8 0.2 2.3 2 1 0 2 2 2 1 short chain dehydrogenase NAD_binding_4 PF07993.12 OAP57164.1 - 0.00076 18.7 0.0 0.054 12.6 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 OAP57164.1 - 0.047 12.8 0.0 0.2 10.7 0.0 1.8 2 0 0 2 2 2 0 RmlD substrate binding domain HLH PF00010.26 OAP57165.1 - 3.9e-15 55.5 0.3 7e-15 54.7 0.3 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF2173 PF09941.9 OAP57165.1 - 0.11 12.8 0.4 0.19 12.0 0.4 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2173) Cyt_bd_oxida_I PF01654.17 OAP57165.1 - 0.15 10.7 0.0 0.2 10.2 0.0 1.1 1 0 0 1 1 1 0 Cytochrome bd terminal oxidase subunit I DUF2207 PF09972.9 OAP57166.1 - 0.19 10.4 0.0 0.3 9.8 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) HAND PF09110.11 OAP57166.1 - 0.54 11.0 5.7 2.4 8.9 1.1 2.7 2 0 0 2 2 2 0 HAND PSDC PF12588.8 OAP57167.1 - 8.1e-57 191.1 0.0 1.2e-56 190.6 0.0 1.3 1 0 0 1 1 1 1 Phophatidylserine decarboxylase PS_Dcarbxylase PF02666.15 OAP57167.1 - 9.1e-38 129.8 0.0 2.5e-37 128.4 0.0 1.6 2 0 0 2 2 2 1 Phosphatidylserine decarboxylase Biotin_lipoyl_2 PF13533.6 OAP57167.1 - 0.00071 19.4 0.5 0.06 13.2 0.2 2.3 2 0 0 2 2 2 2 Biotin-lipoyl like Peptidase_M23 PF01551.22 OAP57167.1 - 0.033 14.4 0.0 0.085 13.1 0.0 1.7 1 0 0 1 1 1 0 Peptidase family M23 HPP PF04982.13 OAP57168.1 - 4e-42 143.3 6.2 4e-42 143.3 6.2 1.8 2 0 0 2 2 2 1 HPP family Peptidase_M1 PF01433.20 OAP57169.1 - 5.9e-46 156.8 0.5 8.9e-46 156.2 0.5 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 OAP57169.1 - 3.6e-37 126.9 0.0 9.5e-37 125.5 0.0 1.8 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 OAP57169.1 - 3.4e-28 99.1 0.0 5.2e-28 98.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_MA_2 PF13485.6 OAP57169.1 - 0.041 13.5 0.0 0.22 11.2 0.0 1.9 2 0 0 2 2 2 0 Peptidase MA superfamily Peptidase_M61 PF05299.12 OAP57169.1 - 1 9.8 4.6 6.4 7.2 2.6 2.9 2 1 0 2 2 2 0 M61 glycyl aminopeptidase Gpr1_Fun34_YaaH PF01184.19 OAP57170.1 - 2.8e-31 108.7 19.3 3.4e-31 108.5 19.3 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family ATP-synt_E PF05680.12 OAP57171.1 - 3.3e-21 75.4 0.1 3.8e-21 75.2 0.1 1.0 1 0 0 1 1 1 1 ATP synthase E chain WD40 PF00400.32 OAP57172.1 - 2.7e-06 28.0 7.1 1.2 10.1 0.5 4.8 4 0 0 4 4 4 3 WD domain, G-beta repeat Spore_III_AF PF09581.10 OAP57172.1 - 0.34 10.9 1.5 0.71 9.9 1.1 1.6 2 0 0 2 2 2 0 Stage III sporulation protein AF (Spore_III_AF) ECM1 PF05782.11 OAP57172.1 - 6 5.7 9.2 8.8 5.1 9.2 1.2 1 0 0 1 1 1 0 Extracellular matrix protein 1 (ECM1) Ureidogly_lyase PF04115.12 OAP57173.1 - 2.8e-55 187.0 0.0 3.3e-55 186.7 0.0 1.1 1 0 0 1 1 1 1 Ureidoglycolate lyase zf-RING_2 PF13639.6 OAP57174.1 - 3.7e-08 33.6 4.0 7.8e-08 32.5 4.0 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 OAP57174.1 - 1.9e-06 28.0 3.2 5.6e-06 26.5 3.2 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 OAP57174.1 - 4.8e-06 26.5 2.0 1.5e-05 25.0 2.0 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 OAP57174.1 - 0.016 15.1 0.6 0.039 13.8 0.6 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-Di19 PF05605.12 OAP57174.1 - 0.023 15.0 0.2 14 6.1 0.0 2.8 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-RING_UBOX PF13445.6 OAP57174.1 - 0.052 13.6 2.1 0.12 12.4 2.1 1.7 1 0 0 1 1 1 0 RING-type zinc-finger Prok-RING_4 PF14447.6 OAP57174.1 - 0.058 13.3 3.5 7 6.6 0.0 3.1 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 PHD PF00628.29 OAP57174.1 - 0.12 12.3 2.4 0.22 11.4 2.4 1.5 1 0 0 1 1 1 0 PHD-finger FANCL_C PF11793.8 OAP57174.1 - 0.18 12.0 2.8 0.49 10.6 2.8 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_2 PF13923.6 OAP57174.1 - 0.47 10.3 7.4 4.4 7.2 7.5 2.4 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 OAP57174.1 - 1.3 8.9 4.7 20 5.1 5.3 2.3 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Rad50_zn_hook PF04423.14 OAP57174.1 - 2.1 8.2 3.4 24 4.9 0.1 3.0 3 0 0 3 3 3 0 Rad50 zinc hook motif Prok-RING_1 PF14446.6 OAP57174.1 - 2.6 8.0 7.4 3.4 7.7 4.4 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 bPH_6 PF10756.9 OAP57176.1 - 0.00094 19.2 0.9 8 6.6 0.0 3.5 1 1 2 3 3 3 3 Bacterial PH domain Ion_trans_2 PF07885.16 OAP57178.1 - 2.8e-28 97.7 24.5 9.2e-15 54.4 6.5 3.2 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.31 OAP57178.1 - 4.8e-05 22.7 9.0 0.0024 17.1 2.6 2.6 2 1 0 2 2 2 2 Ion transport protein HCV_NS4a PF01006.20 OAP57178.1 - 0.78 9.5 4.6 16 5.3 0.2 3.0 3 0 0 3 3 3 0 Hepatitis C virus non-structural protein NS4a ODV-E18 PF10717.9 OAP57179.1 - 0.33 10.8 1.3 0.38 10.6 0.0 1.7 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 ATP-synt PF00231.19 OAP57181.1 - 2.6e-76 257.0 1.3 3.1e-76 256.8 1.3 1.0 1 0 0 1 1 1 1 ATP synthase Topoisom_I_N PF02919.15 OAP57182.1 - 4.8e-95 317.1 3.9 4.8e-95 317.1 3.9 3.6 4 0 0 4 4 4 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.20 OAP57182.1 - 2.9e-90 301.6 5.1 2.9e-90 301.6 5.1 2.1 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.6 OAP57182.1 - 1.1e-32 111.8 1.2 1.1e-32 111.8 1.2 2.5 2 0 0 2 2 2 1 C-terminal topoisomerase domain CBFB_NFYA PF02045.15 OAP57183.1 - 5.7e-29 100.5 4.6 1.2e-28 99.5 4.6 1.6 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Hus1 PF04005.12 OAP57183.1 - 0.021 13.9 0.0 0.036 13.2 0.0 1.3 1 0 0 1 1 1 0 Hus1-like protein UBA2_C PF16195.5 OAP57183.1 - 0.36 11.5 9.9 0.067 13.9 5.2 2.1 2 0 0 2 2 2 0 SUMO-activating enzyme subunit 2 C-terminus DUF3818 PF12825.7 OAP57184.1 - 4.8e-131 436.8 0.8 7e-131 436.3 0.8 1.3 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) RRN3 PF05327.11 OAP57184.1 - 0.014 13.9 2.2 0.3 9.6 0.2 2.2 1 1 1 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 PXB PF12828.7 OAP57185.1 - 1.6e-39 134.8 1.2 2.1e-39 134.5 1.2 1.1 1 0 0 1 1 1 1 PX-associated PX PF00787.24 OAP57185.1 - 5.9e-10 39.1 0.5 1.3e-09 38.0 0.1 1.7 2 0 0 2 2 2 1 PX domain ADH_zinc_N PF00107.26 OAP57186.1 - 5.1e-10 39.4 0.0 9.7e-10 38.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAP57186.1 - 0.00017 21.4 0.1 0.00048 20.0 0.1 1.7 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 OAP57186.1 - 0.0043 18.1 0.0 0.0094 17.0 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PEP_mutase PF13714.6 OAP57186.1 - 0.066 12.7 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate phosphomutase S4 PF01479.25 OAP57187.1 - 1.4e-10 40.7 0.2 3.4e-10 39.5 0.1 1.8 2 0 0 2 2 2 1 S4 domain Ribosomal_S4 PF00163.19 OAP57187.1 - 3.5e-09 37.4 0.2 6e-09 36.7 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain MFS_1 PF07690.16 OAP57189.1 - 7.2e-12 44.9 3.9 7.7e-12 44.8 3.9 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAP57189.1 - 7.4e-05 21.8 1.6 7.4e-05 21.8 1.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter PCNA_C PF02747.15 OAP57190.1 - 0.16 12.1 0.0 0.29 11.3 0.0 1.3 1 0 0 1 1 1 0 Proliferating cell nuclear antigen, C-terminal domain Sugar_tr PF00083.24 OAP57191.1 - 1.2e-89 301.3 18.1 1.4e-89 301.0 18.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP57191.1 - 3.8e-15 55.7 36.0 4.7e-13 48.8 29.2 2.6 1 1 2 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.6 OAP57191.1 - 5e-05 22.0 19.3 0.0052 15.4 2.1 2.9 3 0 0 3 3 3 2 MFS/sugar transport protein MFS_1_like PF12832.7 OAP57191.1 - 0.35 9.7 10.2 0.46 9.3 1.1 2.3 2 0 0 2 2 2 0 MFS_1 like family Alpha-amylase PF00128.24 OAP57192.1 - 1.3e-112 376.7 0.1 2.2e-112 376.0 0.1 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.6 OAP57192.1 - 0.0093 15.1 0.1 0.018 14.1 0.1 1.4 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain Glyco_hydro_70 PF02324.16 OAP57192.1 - 0.14 10.3 0.1 0.21 9.7 0.1 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 70 NmrA PF05368.13 OAP57193.1 - 2.2e-27 96.1 0.0 2.8e-27 95.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAP57193.1 - 2.7e-08 33.9 0.1 7.7e-08 32.4 0.0 1.7 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 OAP57193.1 - 0.001 18.6 0.0 0.0017 17.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 OAP57193.1 - 0.073 13.3 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain F420_oxidored PF03807.17 OAP57193.1 - 0.2 12.3 0.0 0.36 11.4 0.0 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Amidase PF01425.21 OAP57194.1 - 3.9e-71 240.4 0.0 1e-70 239.0 0.0 1.6 1 1 0 1 1 1 1 Amidase Methyltransf_2 PF00891.18 OAP57195.1 - 1.2e-20 73.8 0.4 6.2e-20 71.4 0.4 2.1 1 1 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 OAP57195.1 - 0.096 12.7 0.1 0.24 11.4 0.1 1.7 1 0 0 1 1 1 0 Dimerisation domain FMO-like PF00743.19 OAP57196.1 - 7.7e-31 107.1 0.0 2.1e-22 79.2 0.0 2.3 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 OAP57196.1 - 1.1e-18 67.5 0.0 9e-16 57.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAP57196.1 - 1.4e-15 57.3 0.3 1.7e-13 50.4 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 OAP57196.1 - 2.3e-15 56.7 0.0 5e-07 29.3 0.0 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAP57196.1 - 1.2e-07 31.8 0.1 2e-05 24.7 0.0 3.0 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 OAP57196.1 - 3.4e-06 27.1 0.6 0.019 14.9 0.1 3.5 3 1 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox PF00070.27 OAP57196.1 - 0.00028 21.4 0.6 0.48 11.0 0.5 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAP57196.1 - 0.00031 20.1 0.1 0.023 14.0 0.1 2.5 3 0 0 3 3 3 1 Thi4 family FAD_binding_3 PF01494.19 OAP57196.1 - 0.001 18.4 0.9 0.031 13.5 0.2 2.6 3 0 0 3 3 3 1 FAD binding domain HI0933_like PF03486.14 OAP57196.1 - 0.0012 17.6 1.1 0.018 13.8 0.3 2.6 3 0 0 3 3 3 1 HI0933-like protein FAD_oxidored PF12831.7 OAP57196.1 - 0.0024 17.3 0.0 0.0024 17.3 0.0 1.5 2 0 0 2 2 1 1 FAD dependent oxidoreductase DAO PF01266.24 OAP57196.1 - 0.0027 17.4 4.6 0.61 9.6 0.2 3.8 2 2 1 4 4 4 1 FAD dependent oxidoreductase Shikimate_DH PF01488.20 OAP57196.1 - 0.0071 16.4 0.1 6 6.9 0.0 2.7 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase Catalase_C PF18011.1 OAP57196.1 - 0.051 13.2 0.8 0.44 10.2 0.2 2.7 2 2 1 3 3 3 0 C-terminal domain found in long catalases NAD_binding_7 PF13241.6 OAP57196.1 - 0.11 12.9 0.1 23 5.5 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding YjbE PF11106.8 OAP57196.1 - 0.15 12.3 4.8 0.33 11.2 4.8 1.6 1 0 0 1 1 1 0 Exopolysaccharide production protein YjbE FAD_binding_2 PF00890.24 OAP57196.1 - 1 8.4 3.9 0.99 8.4 0.9 2.2 2 1 1 3 3 3 0 FAD binding domain SNF2_N PF00176.23 OAP57197.1 - 8.4e-57 192.5 0.0 1.3e-56 191.8 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OAP57197.1 - 7.5e-11 42.4 0.0 1.8e-10 41.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAP57197.1 - 8.6e-07 29.1 0.3 3.8e-06 27.0 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 OAP57197.1 - 0.0003 20.6 0.1 0.0011 18.8 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase zf-RING_5 PF14634.6 OAP57197.1 - 0.001 19.0 11.2 0.0032 17.4 11.2 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 OAP57197.1 - 0.018 15.1 7.6 0.048 13.7 7.6 1.7 1 0 0 1 1 1 0 RING-type zinc-finger Flavi_DEAD PF07652.14 OAP57197.1 - 0.03 14.3 0.1 7.9 6.4 0.0 3.3 3 0 0 3 3 3 0 Flavivirus DEAD domain CEBP_ZZ PF16366.5 OAP57197.1 - 0.094 13.0 4.9 0.23 11.7 4.9 1.6 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain zf-C3HC4_3 PF13920.6 OAP57197.1 - 0.17 11.8 13.9 0.12 12.2 9.6 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OAP57197.1 - 0.33 11.2 10.6 0.72 10.1 10.6 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 OAP57197.1 - 0.55 10.2 13.1 1.7 8.6 13.1 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 OAP57197.1 - 0.63 10.0 3.0 1.8 8.5 3.0 1.7 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_2 PF13639.6 OAP57197.1 - 5 7.5 13.0 4.3 7.7 10.0 2.4 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4_2 PF13923.6 OAP57197.1 - 9.5 6.2 10.8 1.9 8.4 6.6 2.0 2 0 0 2 2 1 0 Zinc finger, C3HC4 type (RING finger) FNIP_N PF14636.6 OAP57198.1 - 2.2e-08 35.2 0.0 2.2e-08 35.2 0.0 5.4 4 2 1 5 5 5 1 Folliculin-interacting protein N-terminus FNIP_M PF14637.6 OAP57198.1 - 0.00039 20.5 0.1 0.0012 18.9 0.0 1.8 1 1 1 2 2 2 1 Folliculin-interacting protein middle domain RAP1 PF07218.11 OAP57198.1 - 0.085 11.1 2.3 0.16 10.2 2.3 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) IML1 PF12257.8 OAP57199.1 - 1.1e-113 379.1 0.0 1.7e-113 378.5 0.0 1.3 1 0 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 DEP PF00610.21 OAP57199.1 - 9.6e-27 92.8 0.2 2.1e-26 91.8 0.2 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) GDA1_CD39 PF01150.17 OAP57200.1 - 1e-51 176.0 0.0 1.3e-51 175.6 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Methyltransf_25 PF13649.6 OAP57202.1 - 1.2e-14 54.7 0.0 2.4e-14 53.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAP57202.1 - 9e-14 51.9 0.0 2e-13 50.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAP57202.1 - 8.5e-12 44.9 0.0 1.2e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 OAP57202.1 - 3.3e-10 39.9 0.0 5e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAP57202.1 - 4.7e-08 33.7 0.0 8.2e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAP57202.1 - 8.1e-07 29.0 0.0 1.2e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OAP57202.1 - 0.011 15.3 0.0 0.017 14.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_8 PF05148.15 OAP57202.1 - 0.24 11.2 0.0 2.1 8.1 0.0 2.0 2 0 0 2 2 2 0 Hypothetical methyltransferase LRV PF01816.17 OAP57202.1 - 0.28 11.7 1.8 0.67 10.5 0.5 2.3 2 0 0 2 2 2 0 Leucine rich repeat variant K_oxygenase PF13434.6 OAP57203.1 - 9.5e-17 61.1 0.0 4.9e-10 39.1 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 OAP57203.1 - 5.2e-10 39.0 0.0 0.0009 18.6 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAP57203.1 - 1.2e-07 31.6 3.1 3.2e-05 23.7 0.0 3.2 2 1 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 OAP57203.1 - 2e-06 27.3 0.0 0.033 13.4 0.0 3.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 OAP57203.1 - 0.0011 18.3 0.5 0.14 11.4 0.1 2.4 2 0 0 2 2 2 2 FAD binding domain Pyr_redox PF00070.27 OAP57203.1 - 0.0015 19.1 0.8 0.19 12.3 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAP57203.1 - 0.0028 17.6 1.2 0.59 10.1 0.0 3.2 3 1 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 OAP57203.1 - 0.0059 16.8 0.6 0.27 11.5 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 OAP57203.1 - 0.011 14.9 0.3 0.036 13.1 0.0 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein ApbA PF02558.16 OAP57203.1 - 0.016 14.9 0.0 0.19 11.4 0.0 2.5 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.14 OAP57203.1 - 0.051 12.3 0.0 0.63 8.7 0.0 2.3 2 0 0 2 2 2 0 HI0933-like protein 3HCDH_N PF02737.18 OAP57203.1 - 0.11 12.4 0.1 10 6.0 0.0 2.5 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.17 OAP57203.1 - 0.32 10.2 1.5 0.34 10.1 0.1 1.7 2 0 0 2 2 2 0 Thi4 family Fungal_trans_2 PF11951.8 OAP57204.1 - 2.2e-58 198.0 0.1 3.6e-58 197.2 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP57204.1 - 4e-05 23.7 5.9 6.8e-05 22.9 5.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain XAP5 PF04921.14 OAP57205.1 - 1.7e-81 273.8 0.0 2.3e-81 273.3 0.0 1.2 1 0 0 1 1 1 1 XAP5, circadian clock regulator DUF4604 PF15377.6 OAP57205.1 - 0.00043 20.7 3.1 0.00043 20.7 3.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4604) V_ATPase_I PF01496.19 OAP57206.1 - 0.065 11.1 1.8 0.069 11.1 1.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Phage_Mu_Gam PF07352.12 OAP57206.1 - 0.25 11.3 5.8 0.4 10.6 5.8 1.3 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein Jnk-SapK_ap_N PF09744.9 OAP57206.1 - 0.93 9.7 12.3 1.5 9.0 12.3 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Exonuc_VII_L PF02601.15 OAP57206.1 - 1.1 8.8 9.8 1.5 8.3 9.8 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit IFT57 PF10498.9 OAP57206.1 - 1.1 8.1 11.9 1.6 7.6 11.9 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 FapA PF03961.13 OAP57206.1 - 1.2 7.6 4.3 1.7 7.2 4.3 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF4407 PF14362.6 OAP57206.1 - 1.3 8.3 9.9 1.9 7.8 9.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) LCD1 PF09798.9 OAP57206.1 - 2.1 6.7 8.5 2.6 6.5 8.5 1.0 1 0 0 1 1 1 0 DNA damage checkpoint protein YlqD PF11068.8 OAP57206.1 - 4.5 7.7 13.6 8.1 6.8 13.6 1.4 1 0 0 1 1 1 0 YlqD protein FAD_binding_4 PF01565.23 OAP57207.1 - 1.4e-15 57.3 0.0 2.3e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Fip1 PF05182.13 OAP57208.1 - 1.4e-22 78.9 1.1 3.9e-22 77.5 1.1 1.7 1 0 0 1 1 1 1 Fip1 motif BLM_N PF16202.5 OAP57208.1 - 1 8.4 6.0 1.7 7.6 6.0 1.4 1 0 0 1 1 1 0 N-terminal region of Bloom syndrome protein Cpn10 PF00166.21 OAP57209.1 - 1.8e-27 95.2 0.0 2e-27 95.1 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Exo84_C PF16528.5 OAP57210.1 - 2.3e-60 203.9 0.6 2.3e-60 203.9 0.6 1.8 2 0 0 2 2 2 1 Exocyst component 84 C-terminal Vps51 PF08700.11 OAP57210.1 - 1.8e-16 60.0 3.2 4.8e-16 58.6 3.2 1.8 1 0 0 1 1 1 1 Vps51/Vps67 JMY PF15871.5 OAP57210.1 - 1.6 8.0 8.5 0.12 11.6 3.2 1.7 2 0 0 2 2 2 0 Junction-mediating and -regulatory protein HIP1_clath_bdg PF16515.5 OAP57210.1 - 1.8 9.2 9.1 0.79 10.4 2.8 2.7 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 ThylakoidFormat PF11264.8 OAP57210.1 - 2 8.1 10.4 0.65 9.6 1.1 2.6 3 0 0 3 3 3 0 Thylakoid formation protein APG6_N PF17675.1 OAP57210.1 - 5.6 7.5 16.2 3.7 8.1 2.1 2.6 3 0 0 3 3 3 0 Apg6 coiled-coil region AA_permease PF00324.21 OAP57211.1 - 1.5e-134 449.2 34.2 1.9e-134 448.9 34.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAP57211.1 - 1.9e-40 139.0 36.9 2.5e-40 138.6 36.9 1.0 1 0 0 1 1 1 1 Amino acid permease Glyco_hydro_1 PF00232.18 OAP57212.1 - 2.7e-79 266.7 1.3 4.8e-77 259.3 1.3 2.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 1 HET PF06985.11 OAP57213.1 - 1.8e-28 99.7 0.0 3e-28 99.0 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ABC2_membrane PF01061.24 OAP57214.1 - 3.6e-84 281.4 43.5 3.2e-45 154.1 20.3 2.9 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 OAP57214.1 - 2.3e-37 128.5 0.0 1.8e-17 64.2 0.0 3.2 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.12 OAP57214.1 - 3.9e-34 116.4 3.3 1e-29 102.3 0.1 3.2 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.6 OAP57214.1 - 5.2e-13 49.4 0.2 5.2e-13 49.4 0.2 2.1 2 0 0 2 2 2 1 ABC-transporter N-terminal AAA_16 PF13191.6 OAP57214.1 - 8.4e-07 29.5 0.1 0.0025 18.2 0.1 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.6 OAP57214.1 - 1.3e-06 28.1 0.1 1.8e-05 24.4 0.1 2.5 2 1 0 2 2 2 1 AAA domain AAA_21 PF13304.6 OAP57214.1 - 6.5e-06 26.2 0.0 0.082 12.7 0.0 3.4 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.6 OAP57214.1 - 2.9e-05 24.3 0.1 0.14 12.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 OAP57214.1 - 6.9e-05 22.5 1.0 0.0074 16.0 0.2 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 OAP57214.1 - 7.7e-05 22.7 0.1 0.0041 17.0 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase SMC_N PF02463.19 OAP57214.1 - 0.00019 20.9 0.0 0.56 9.6 0.0 3.9 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 OAP57214.1 - 0.00083 19.6 0.1 0.87 9.9 0.0 3.7 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.6 OAP57214.1 - 0.002 18.6 0.2 1.7 9.1 0.0 3.8 4 0 0 4 4 4 1 AAA domain AAA_18 PF13238.6 OAP57214.1 - 0.007 16.9 0.0 0.48 11.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 OAP57214.1 - 0.0073 15.9 0.9 0.23 11.0 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain ABC2_membrane_3 PF12698.7 OAP57214.1 - 0.012 14.7 39.3 0.048 12.8 12.1 2.6 2 1 0 2 2 2 0 ABC-2 family transporter protein AAA_23 PF13476.6 OAP57214.1 - 0.026 15.0 0.0 0.17 12.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 OAP57214.1 - 0.074 12.8 0.1 4.4 7.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 OAP57214.1 - 0.086 12.7 0.7 4.5 7.2 0.3 2.6 2 0 0 2 2 2 0 NACHT domain AAA_24 PF13479.6 OAP57214.1 - 0.1 12.3 0.7 7.8 6.2 0.2 2.5 2 0 0 2 2 2 0 AAA domain CCDC24 PF15669.5 OAP57216.1 - 0.02 14.7 0.7 0.02 14.7 0.7 2.4 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 24 family DUF3425 PF11905.8 OAP57217.1 - 3e-12 46.6 0.0 5.8e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 OAP57217.1 - 0.00011 22.3 12.2 0.00051 20.1 12.2 2.0 1 1 0 1 1 1 1 bZIP transcription factor Csm1_N PF18504.1 OAP57217.1 - 0.0032 17.8 1.1 0.0032 17.8 1.1 2.0 2 0 0 2 2 2 1 Csm1 N-terminal domain DUF1366 PF07104.11 OAP57217.1 - 0.16 11.7 0.0 0.29 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1366) bZIP_2 PF07716.15 OAP57217.1 - 0.2 11.8 9.2 0.17 12.0 2.6 2.3 2 0 0 2 2 2 0 Basic region leucine zipper FMO-like PF00743.19 OAP57218.1 - 2.5e-16 59.2 0.8 1e-14 53.9 0.1 2.5 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OAP57218.1 - 1e-11 44.9 0.0 2.3e-11 43.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 OAP57218.1 - 0.00039 19.8 0.1 0.0046 16.3 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAP57218.1 - 0.0004 19.6 0.0 0.015 14.5 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 OAP57218.1 - 0.0067 16.4 0.0 0.28 11.1 0.0 2.8 3 0 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.17 OAP57218.1 - 0.022 14.0 0.0 0.071 12.3 0.0 1.7 2 0 0 2 2 2 0 Thi4 family DAO PF01266.24 OAP57218.1 - 0.099 12.2 0.0 4 6.9 0.0 2.7 1 1 2 3 3 3 0 FAD dependent oxidoreductase Shikimate_DH PF01488.20 OAP57218.1 - 0.21 11.6 0.0 0.58 10.2 0.0 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase adh_short_C2 PF13561.6 OAP57219.1 - 5.1e-52 176.8 0.4 5.9e-52 176.6 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP57219.1 - 6.9e-44 149.6 0.1 8.4e-44 149.4 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAP57219.1 - 5e-05 23.3 0.2 0.00014 21.8 0.2 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 OAP57219.1 - 0.0069 15.9 0.0 0.19 11.2 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 OAP57219.1 - 0.035 13.4 0.0 0.061 12.6 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Eno-Rase_NADH_b PF12242.8 OAP57219.1 - 0.071 12.9 0.5 0.18 11.6 0.5 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase TRI12 PF06609.13 OAP57220.1 - 1.4e-32 112.9 29.8 1.8e-32 112.6 29.8 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAP57220.1 - 1.4e-18 66.9 53.8 1.4e-18 66.9 53.8 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily FAD_oxidored PF12831.7 OAP57221.1 - 6.1e-65 220.3 4.9 2.3e-63 215.1 4.9 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OAP57221.1 - 7.2e-07 28.6 4.1 1.6e-05 24.2 1.3 2.3 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 OAP57221.1 - 3.8e-05 23.1 0.1 5.7e-05 22.5 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OAP57221.1 - 9.4e-05 21.7 0.3 0.00014 21.1 0.3 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.27 OAP57221.1 - 0.00013 22.4 0.4 0.00032 21.2 0.4 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAP57221.1 - 0.00089 18.9 3.8 0.0012 18.6 2.7 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 OAP57221.1 - 0.0012 18.2 0.7 0.0026 17.1 0.7 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain DUF5329 PF17263.2 OAP57221.1 - 0.013 15.7 0.1 0.026 14.7 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5329) HI0933_like PF03486.14 OAP57221.1 - 0.02 13.6 0.3 0.032 12.9 0.3 1.3 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_8 PF13450.6 OAP57221.1 - 0.029 14.6 0.8 0.029 14.6 0.8 2.3 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 OAP57221.1 - 0.098 11.9 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HET PF06985.11 OAP57222.1 - 7.2e-06 26.4 0.8 2.2e-05 24.9 0.1 2.1 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Ost4 PF10215.9 OAP57223.1 - 1.4e-18 66.4 2.8 2.2e-18 65.8 2.8 1.2 1 0 0 1 1 1 1 Oligosaccaryltransferase PIF6 PF05341.11 OAP57224.1 - 0.076 13.1 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Per os infectivity factor 6 FOXP-CC PF16159.5 OAP57225.1 - 0.034 14.8 0.8 0.034 14.8 0.8 2.4 2 0 0 2 2 2 0 FOXP coiled-coil domain SLC12 PF03522.15 OAP57225.1 - 3.2 6.7 7.7 7.1 5.5 7.7 1.5 1 0 0 1 1 1 0 Solute carrier family 12 Ribosomal_L26 PF16906.5 OAP57226.1 - 3.8e-38 129.8 3.1 4.7e-38 129.5 3.1 1.1 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 OAP57226.1 - 1.7e-07 30.9 0.2 1.7e-07 30.9 0.2 1.8 2 0 0 2 2 2 1 KOW motif DUF1223 PF06764.11 OAP57226.1 - 0.15 12.1 0.1 0.17 11.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1223) MIP PF00230.20 OAP57227.1 - 1.3e-29 103.6 6.3 1.9e-29 103.0 6.3 1.2 1 0 0 1 1 1 1 Major intrinsic protein SKG6 PF08693.10 OAP57227.1 - 2.3 7.7 4.4 2.8 7.4 3.0 1.9 1 1 0 1 1 1 0 Transmembrane alpha-helix domain adh_short PF00106.25 OAP57228.1 - 3e-28 98.6 0.1 3.6e-28 98.4 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP57228.1 - 2.5e-22 79.6 0.1 3.3e-22 79.2 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP57228.1 - 1.5e-06 28.2 0.1 2e-06 27.8 0.1 1.2 1 0 0 1 1 1 1 KR domain DUF460 PF04312.13 OAP57228.1 - 0.051 13.3 0.0 0.072 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF460) DUF1776 PF08643.10 OAP57228.1 - 0.13 11.6 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) DUF4396 PF14342.6 OAP57229.1 - 2.8e-36 125.0 13.6 5.6e-36 124.0 13.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4396) Fungal_trans_2 PF11951.8 OAP57230.1 - 6.4e-06 25.2 0.1 0.0011 17.9 0.1 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Acyltransferase PF01553.21 OAP57231.1 - 8.3e-17 61.1 0.0 2.2e-16 59.7 0.0 1.7 1 0 0 1 1 1 1 Acyltransferase HK PF02110.15 OAP57231.1 - 0.026 13.9 0.0 0.47 9.8 0.0 2.2 2 0 0 2 2 2 0 Hydroxyethylthiazole kinase family Peptidase_M24 PF00557.24 OAP57234.1 - 2.7e-23 82.8 0.0 3.2e-23 82.5 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 LRR_9 PF14580.6 OAP57235.1 - 1e-58 197.7 0.1 1.5e-58 197.1 0.1 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 OAP57235.1 - 3.4e-07 30.5 3.9 0.0001 22.6 0.1 3.5 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OAP57235.1 - 8.8e-06 25.4 0.6 8.8e-06 25.4 0.6 3.1 3 1 1 4 4 4 1 Leucine rich repeat PrpR_N PF06506.11 OAP57235.1 - 0.007 16.0 0.1 0.011 15.3 0.1 1.3 1 0 0 1 1 1 1 Propionate catabolism activator LRR_6 PF13516.6 OAP57235.1 - 0.92 9.7 4.7 18 5.7 0.2 4.1 4 0 0 4 4 4 0 Leucine Rich repeat GATase PF00117.28 OAP57236.1 - 9.1e-10 38.6 0.0 1.3e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 OAP57236.1 - 0.0084 15.7 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain MFS_1 PF07690.16 OAP57237.1 - 9.7e-31 107.0 36.3 1.5e-30 106.3 33.5 2.1 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAP57237.1 - 9.7e-05 21.4 6.4 9.7e-05 21.4 6.4 2.7 2 0 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 OAP57237.1 - 6.5 4.9 12.8 6.5 4.9 2.9 3.4 3 2 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family TPP_enzyme_N PF02776.18 OAP57238.1 - 5e-36 123.9 0.5 8.4e-36 123.2 0.5 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 OAP57238.1 - 1.3e-15 57.5 0.6 2.5e-11 43.6 0.1 3.3 2 1 0 2 2 2 2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 OAP57238.1 - 3.6e-12 46.2 0.0 7.1e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain Na_Ca_ex PF01699.24 OAP57239.1 - 4.3e-44 150.1 37.4 5.4e-22 78.4 12.0 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein HCV_core PF01542.18 OAP57239.1 - 1.7 9.1 5.6 0.41 11.1 0.8 2.3 2 0 0 2 2 2 0 Hepatitis C virus core protein ATP_bind_3 PF01171.20 OAP57240.1 - 3.3e-36 124.8 0.0 8.2e-36 123.5 0.0 1.7 1 1 0 1 1 1 1 PP-loop family DIOX_N PF14226.6 OAP57241.1 - 1.5e-15 58.0 0.0 2.6e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OAP57241.1 - 1.7e-14 54.1 0.0 2.9e-14 53.4 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily RRN3 PF05327.11 OAP57242.1 - 1.2e-154 516.0 0.3 1.4e-154 515.7 0.3 1.1 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 SIMPL PF04402.14 OAP57243.1 - 3.3e-24 86.5 0.2 4.1e-24 86.2 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF541) Sugar_tr PF00083.24 OAP57244.1 - 6.4e-82 275.8 22.3 7.2e-82 275.6 22.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP57244.1 - 1.9e-23 83.0 57.3 2.9e-22 79.1 32.8 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3425 PF11905.8 OAP57245.1 - 3.7e-17 62.5 0.8 7.9e-17 61.4 0.8 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Baseplate_J PF04865.14 OAP57245.1 - 0.15 11.2 0.1 0.24 10.5 0.1 1.2 1 0 0 1 1 1 0 Baseplate J-like protein bZIP_1 PF00170.21 OAP57245.1 - 1.9 8.6 6.5 3.3 7.9 6.5 1.3 1 0 0 1 1 1 0 bZIP transcription factor NmrA PF05368.13 OAP57246.1 - 1.5e-31 109.8 0.0 2.3e-31 109.2 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAP57246.1 - 6.6e-10 39.2 0.0 1.1e-09 38.5 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAP57246.1 - 5.9e-06 25.9 0.0 2.1e-05 24.1 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 OAP57246.1 - 0.0039 17.4 0.0 0.0066 16.7 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain adh_short PF00106.25 OAP57246.1 - 0.1 12.1 0.0 0.23 10.9 0.0 1.6 2 0 0 2 2 2 0 short chain dehydrogenase Sacchrp_dh_NADP PF03435.18 OAP57246.1 - 0.19 12.0 0.0 0.32 11.2 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Xan_ur_permease PF00860.20 OAP57247.1 - 7.9e-22 77.5 24.6 3.7e-21 75.3 24.6 2.0 1 1 0 1 1 1 1 Permease family MFS_MOT1 PF16983.5 OAP57247.1 - 0.59 10.6 12.9 0.31 11.5 1.1 3.0 2 0 0 2 2 2 0 Molybdate transporter of MFS superfamily Pox_A32 PF04665.12 OAP57247.1 - 1 8.8 1.9 0.75 9.2 0.2 1.5 2 0 0 2 2 2 0 Poxvirus A32 protein Methyltransf_31 PF13847.6 OAP57248.1 - 0.013 15.3 0.0 0.022 14.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 OAP57248.1 - 0.098 13.3 0.0 0.2 12.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Fcf1 PF04900.12 OAP57249.1 - 7.7e-14 51.9 3.0 1.3e-12 47.9 3.0 2.6 1 1 0 1 1 1 1 Fcf1 Tmemb_14 PF03647.13 OAP57250.1 - 7.6e-25 87.5 7.9 8.8e-25 87.3 7.9 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C Aim19 PF10315.9 OAP57250.1 - 0.0026 18.1 0.9 0.0087 16.3 0.9 1.9 1 1 0 1 1 1 1 Altered inheritance of mitochondria protein 19 GMC_oxred_N PF00732.19 OAP57251.1 - 1.7e-55 188.5 0.0 2.4e-55 188.0 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAP57251.1 - 3.1e-33 115.3 0.0 5.4e-33 114.5 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 OAP57251.1 - 2.6e-05 24.4 0.2 6.5e-05 23.1 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 OAP57251.1 - 0.014 14.5 0.4 0.023 13.8 0.4 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_2 PF07992.14 OAP57251.1 - 0.038 13.2 0.3 0.13 11.4 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAP57251.1 - 0.11 11.5 5.2 0.024 13.7 1.8 1.5 2 0 0 2 2 2 0 FAD binding domain DAO PF01266.24 OAP57251.1 - 0.3 10.6 3.5 0.19 11.3 0.9 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase DAD PF02109.16 OAP57252.1 - 1.3e-43 147.8 0.0 1.7e-43 147.4 0.0 1.2 1 0 0 1 1 1 1 DAD family SET PF00856.28 OAP57253.1 - 9.3e-10 39.1 0.1 5.3e-09 36.7 0.0 2.3 2 1 0 2 2 2 1 SET domain Fungal_trans PF04082.18 OAP57254.1 - 1.3e-59 201.5 0.0 2e-59 200.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 OAP57254.1 - 0.00017 21.9 13.7 0.0027 18.1 2.9 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OAP57254.1 - 0.0071 16.7 2.3 0.0071 16.7 2.3 2.7 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 OAP57254.1 - 0.027 15.3 11.5 0.24 12.4 2.4 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger GFA PF04828.14 OAP57255.1 - 0.00024 21.4 0.1 0.00024 21.4 0.1 1.7 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Rot1 PF10681.9 OAP57256.1 - 5.6e-97 323.3 0.5 6.5e-97 323.1 0.5 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal 5-FTHF_cyc-lig PF01812.20 OAP57257.1 - 4.9e-34 117.8 0.0 1.1e-33 116.7 0.0 1.5 1 1 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family LSM PF01423.22 OAP57258.1 - 1.9e-14 53.1 0.1 2.2e-14 52.9 0.1 1.1 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 OAP57258.1 - 0.0042 16.7 0.0 0.0065 16.1 0.0 1.3 1 0 0 1 1 1 1 Hfq protein PhnA PF03831.14 OAP57258.1 - 0.032 14.1 0.1 1.5 8.8 0.1 2.3 2 1 0 2 2 2 0 PhnA domain Xpo1 PF08389.12 OAP57259.1 - 7.1e-27 94.3 0.2 8.6e-26 90.8 0.1 3.0 2 1 0 2 2 2 1 Exportin 1-like protein IBN_N PF03810.19 OAP57259.1 - 1.2e-08 34.7 0.6 3.6e-08 33.2 0.1 2.1 2 0 0 2 2 2 1 Importin-beta N-terminal domain UME PF08064.13 OAP57259.1 - 0.031 14.2 0.6 2.7 8.0 0.0 3.9 4 0 0 4 4 4 0 UME (NUC010) domain HEAT PF02985.22 OAP57259.1 - 0.29 11.5 3.0 24 5.5 0.0 4.6 4 0 0 4 4 4 0 HEAT repeat Mito_carr PF00153.27 OAP57260.1 - 4.8e-49 164.2 3.3 1.1e-18 66.9 0.3 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein zf-ZPR1 PF03367.13 OAP57261.1 - 2.2e-105 349.4 0.0 1.9e-55 187.0 0.0 2.1 2 0 0 2 2 2 2 ZPR1 zinc-finger domain zinc-ribbons_6 PF07191.12 OAP57261.1 - 0.056 13.4 2.9 0.5 10.4 0.5 2.3 2 0 0 2 2 2 0 zinc-ribbons HypA PF01155.19 OAP57261.1 - 0.14 12.1 2.7 1.7 8.7 0.3 2.4 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-ribbon_3 PF13248.6 OAP57261.1 - 0.19 11.2 11.5 6.1 6.4 0.1 3.5 3 0 0 3 3 3 0 zinc-ribbon domain Lar_restr_allev PF14354.6 OAP57261.1 - 0.2 12.1 6.9 0.51 10.7 1.1 2.6 2 1 0 2 2 2 0 Restriction alleviation protein Lar E7 PF00527.18 OAP57261.1 - 2.6 8.3 8.9 1.4 9.2 0.2 2.8 3 0 0 3 3 3 0 E7 protein, Early protein Rubredoxin_2 PF18073.1 OAP57261.1 - 4.4 7.1 11.4 6 6.7 0.2 3.5 3 0 0 3 3 3 0 Rubredoxin metal binding domain DZR PF12773.7 OAP57261.1 - 9.3 6.4 10.8 7.2 6.7 2.7 3.3 2 2 1 3 3 3 0 Double zinc ribbon Rpr2 PF04032.16 OAP57262.1 - 5.9e-07 29.7 1.7 1.7e-06 28.2 1.7 1.8 1 1 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain PLATZ PF04640.14 OAP57262.1 - 0.0051 17.4 0.6 6 7.6 1.0 2.5 1 1 1 2 2 2 2 PLATZ transcription factor CTU2 PF10288.9 OAP57262.1 - 0.077 13.2 2.8 0.77 10.0 2.8 2.1 1 1 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 RNA_POL_M_15KD PF02150.16 OAP57262.1 - 0.2 11.6 0.1 0.2 11.6 0.1 1.7 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit Fungal_trans_2 PF11951.8 OAP57263.1 - 2.6e-08 33.1 0.4 0.00087 18.2 0.3 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain bZIP_1 PF00170.21 OAP57264.1 - 4.3e-10 39.5 10.6 1.7e-09 37.7 6.7 2.4 2 1 1 3 3 3 2 bZIP transcription factor UPF0242 PF06785.11 OAP57264.1 - 0.00089 19.4 0.9 0.0012 18.9 0.9 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus ASD2 PF08687.11 OAP57264.1 - 0.0015 18.1 1.0 0.0019 17.8 1.0 1.1 1 0 0 1 1 1 1 Apx/Shroom domain ASD2 bZIP_Maf PF03131.17 OAP57264.1 - 0.003 18.0 7.9 0.005 17.3 7.9 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_2 PF07716.15 OAP57264.1 - 0.012 15.7 9.2 0.038 14.1 4.5 2.2 1 1 1 2 2 2 0 Basic region leucine zipper CCDC92 PF14916.6 OAP57264.1 - 0.037 13.8 2.9 0.089 12.6 2.9 1.6 1 0 0 1 1 1 0 Coiled-coil domain of unknown function ABC_tran_CTD PF16326.5 OAP57264.1 - 0.14 12.4 3.4 0.51 10.6 3.4 1.9 1 1 0 1 1 1 0 ABC transporter C-terminal domain DUF1192 PF06698.11 OAP57264.1 - 0.64 10.1 3.8 4.5 7.4 0.2 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1192) adh_short PF00106.25 OAP57265.1 - 2.3e-20 72.9 0.1 4.6e-17 62.1 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAP57265.1 - 2.6e-11 43.5 0.5 1.5e-10 41.1 0.1 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP57265.1 - 0.00057 19.8 0.1 0.00096 19.1 0.1 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OAP57265.1 - 0.13 11.4 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DBR1 PF05011.13 OAP57266.1 - 1.5e-41 142.1 0.1 3.5e-41 140.9 0.0 1.7 2 0 0 2 2 2 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 OAP57266.1 - 5.1e-05 23.9 1.2 8.3e-05 23.2 1.2 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase ORC6 PF05460.13 OAP57267.1 - 2.9e-35 122.2 0.0 2.2e-32 112.7 0.0 2.0 1 1 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) Ribosomal_60s PF00428.19 OAP57267.1 - 0.016 15.7 0.3 0.049 14.2 0.1 2.0 2 0 0 2 2 2 0 60s Acidic ribosomal protein NOA36 PF06524.12 OAP57267.1 - 2.5 7.3 6.0 4.6 6.5 6.0 1.4 1 0 0 1 1 1 0 NOA36 protein Methyltransf_24 PF13578.6 OAP57269.1 - 2.8e-10 41.2 0.0 5.9e-10 40.1 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_3 PF01596.17 OAP57269.1 - 2.7e-05 23.5 0.0 6e-05 22.3 0.0 1.5 1 1 0 1 1 1 1 O-methyltransferase CmcI PF04989.12 OAP57269.1 - 0.087 12.5 0.0 0.14 11.8 0.0 1.5 2 0 0 2 2 2 0 Cephalosporin hydroxylase Peptidase_C14 PF00656.22 OAP57270.1 - 9.1e-08 32.3 0.0 2.3e-07 31.0 0.0 1.5 1 1 0 1 1 1 1 Caspase domain Raptor_N PF14538.6 OAP57270.1 - 0.04 13.9 0.0 0.1 12.5 0.0 1.7 1 0 0 1 1 1 0 Raptor N-terminal CASPase like domain DUF1837 PF08878.11 OAP57270.1 - 0.097 12.5 0.2 0.32 10.8 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1837) PfkB PF00294.24 OAP57271.1 - 2.1e-35 122.5 0.0 2.3e-30 106.0 0.0 2.1 2 0 0 2 2 2 2 pfkB family carbohydrate kinase IU_nuc_hydro PF01156.19 OAP57272.1 - 1.4e-76 258.0 0.0 1.7e-76 257.7 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase AA_permease_2 PF13520.6 OAP57273.1 - 7.6e-64 216.1 53.7 9.4e-64 215.8 53.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAP57273.1 - 3.5e-20 72.1 45.2 4.7e-20 71.6 45.2 1.1 1 0 0 1 1 1 1 Amino acid permease B12D PF06522.11 OAP57273.1 - 0.18 11.7 1.4 4.9 7.0 1.2 2.8 2 0 0 2 2 2 0 NADH-ubiquinone reductase complex 1 MLRQ subunit Amidohydro_1 PF01979.20 OAP57274.1 - 2.1e-64 218.0 0.2 2.7e-64 217.7 0.2 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 OAP57274.1 - 1.1e-08 35.0 0.4 2.4e-06 27.3 0.1 2.1 2 0 0 2 2 2 2 Amidohydrolase family BtrH_N PF14399.6 OAP57274.1 - 0.026 14.8 0.0 0.13 12.5 0.0 2.0 2 0 0 2 2 2 0 Butirosin biosynthesis protein H, N-terminal 2OG-FeII_Oxy PF03171.20 OAP57275.1 - 0.00013 22.4 0.0 0.00082 19.8 0.0 2.1 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Glyco_hydro_16 PF00722.21 OAP57276.1 - 0.00073 19.1 0.0 0.0012 18.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 HORMA PF02301.18 OAP57277.1 - 2.1e-11 43.8 0.0 3e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 HORMA domain Ceramidase PF05875.12 OAP57278.1 - 3e-102 341.6 12.7 3.5e-102 341.3 12.7 1.0 1 0 0 1 1 1 1 Ceramidase DUF4131 PF13567.6 OAP57278.1 - 0.0013 18.4 0.7 0.85 9.2 0.1 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4131) Prefoldin_2 PF01920.20 OAP57279.1 - 1.7e-16 60.1 6.1 2.2e-16 59.7 6.1 1.2 1 0 0 1 1 1 1 Prefoldin subunit Rootletin PF15035.6 OAP57279.1 - 0.0063 16.6 3.7 0.0099 15.9 0.1 2.0 2 0 0 2 2 2 1 Ciliary rootlet component, centrosome cohesion CCDC-167 PF15188.6 OAP57279.1 - 0.026 14.9 1.7 0.046 14.1 1.7 1.6 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 SurA_N PF09312.11 OAP57279.1 - 0.065 13.3 1.4 0.19 11.8 1.4 1.8 1 1 0 1 1 1 0 SurA N-terminal domain Fib_alpha PF08702.10 OAP57279.1 - 0.17 12.1 4.4 1.3 9.2 0.1 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family SlyX PF04102.12 OAP57279.1 - 0.99 10.1 6.2 5.4 7.7 0.1 2.4 2 0 0 2 2 2 0 SlyX DUF936 PF06075.12 OAP57280.1 - 1.3 7.8 18.8 1.5 7.6 18.8 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) Castor_Poll_mid PF06241.12 OAP57281.1 - 0.16 11.9 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 Castor and Pollux, part of voltage-gated ion channel Tox-HNH-HHH PF15637.6 OAP57282.1 - 0.098 12.8 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif DUF997 PF06196.12 OAP57282.1 - 0.32 11.0 4.3 0.36 10.9 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF997) Neurensin PF14927.6 OAP57282.1 - 1.5 8.6 3.9 0.42 10.3 0.1 2.0 2 1 1 3 3 3 0 Neurensin DEAD PF00270.29 OAP57284.1 - 1.2e-28 100.1 0.0 2.7e-28 98.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1998 PF09369.10 OAP57284.1 - 1.5e-20 73.7 0.3 3.8e-20 72.4 0.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) Helicase_C PF00271.31 OAP57284.1 - 5.1e-12 46.1 0.0 2.6e-11 43.9 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAP57284.1 - 2.2e-07 31.0 0.0 4e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CDT1 PF08839.11 OAP57284.1 - 8.6e-07 29.4 0.0 1.7e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 DNA replication factor CDT1 like IBR PF01485.21 OAP57285.1 - 3.2e-05 24.1 6.7 3.2e-05 24.1 6.7 3.1 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain Acetyltransf_9 PF13527.7 OAP57286.1 - 8.3e-08 32.4 0.2 1.6e-07 31.5 0.2 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OAP57286.1 - 1.5e-07 31.7 0.1 3e-07 30.7 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OAP57286.1 - 1.3e-05 25.2 0.0 2.8e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAP57286.1 - 0.0003 21.0 0.0 0.00064 19.9 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_CG PF14542.6 OAP57286.1 - 0.001 19.2 0.0 0.38 10.9 0.1 2.6 2 0 0 2 2 2 2 GCN5-related N-acetyl-transferase FR47 PF08445.10 OAP57286.1 - 0.0071 16.3 0.0 0.016 15.1 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_15 PF17013.5 OAP57286.1 - 0.17 11.3 0.0 0.24 10.8 0.0 1.2 1 0 0 1 1 1 0 Putative acetyl-transferase FMO-like PF00743.19 OAP57287.1 - 2.8e-20 72.2 0.8 1.8e-17 63.0 0.5 2.6 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OAP57287.1 - 1.3e-08 34.9 0.0 3e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 OAP57287.1 - 2.6e-07 30.1 0.0 3.7e-05 23.0 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 OAP57287.1 - 0.00013 21.3 0.0 0.12 11.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAP57287.1 - 0.00085 19.3 0.0 0.12 12.4 0.0 2.9 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 OAP57287.1 - 0.0042 16.4 0.0 0.028 13.7 0.0 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.23 OAP57287.1 - 0.026 14.5 0.1 5.2 7.0 0.1 2.5 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Thi4 PF01946.17 OAP57287.1 - 0.064 12.5 0.0 0.74 9.0 0.0 2.1 2 0 0 2 2 2 0 Thi4 family XPC-binding PF09280.11 OAP57287.1 - 0.15 11.8 0.4 3.8 7.3 0.0 2.6 2 0 0 2 2 2 0 XPC-binding domain MMR_HSR1 PF01926.23 OAP57288.1 - 3.6e-06 27.0 0.0 1.8e-05 24.8 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 OAP57288.1 - 2.3e-05 24.8 0.2 0.00059 20.3 0.0 3.1 3 1 0 3 3 3 1 AAA ATPase domain AIG1 PF04548.16 OAP57288.1 - 0.00022 20.6 1.2 1.4 8.2 0.0 3.8 4 0 0 4 4 4 2 AIG1 family RsgA_GTPase PF03193.16 OAP57288.1 - 0.0038 17.2 0.2 0.02 14.8 0.0 2.2 2 1 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 OAP57288.1 - 0.0038 16.9 0.0 0.011 15.5 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain Septin PF00735.18 OAP57288.1 - 0.0097 15.2 0.2 0.068 12.4 0.1 2.4 1 1 0 1 1 1 1 Septin AAA_22 PF13401.6 OAP57288.1 - 0.012 15.9 0.1 0.13 12.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 OAP57288.1 - 0.024 14.0 0.1 0.15 11.4 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI G-alpha PF00503.20 OAP57288.1 - 0.039 13.1 0.1 0.13 11.4 0.1 2.0 1 1 0 1 1 1 0 G-protein alpha subunit Dynamin_N PF00350.23 OAP57288.1 - 0.047 13.7 0.1 0.87 9.6 0.1 2.9 1 1 0 1 1 1 0 Dynamin family T2SSE PF00437.20 OAP57288.1 - 0.05 12.7 0.0 0.1 11.6 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein GTP_EFTU PF00009.27 OAP57288.1 - 0.058 12.9 0.3 0.18 11.3 0.1 1.9 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain NACHT PF05729.12 OAP57288.1 - 0.06 13.3 0.0 0.19 11.6 0.0 1.8 1 0 0 1 1 1 0 NACHT domain AAA_7 PF12775.7 OAP57288.1 - 0.084 12.4 0.0 0.23 10.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 OAP57288.1 - 0.086 13.3 2.1 0.32 11.5 0.0 2.9 3 0 0 3 3 3 0 ABC transporter AAA_24 PF13479.6 OAP57288.1 - 0.12 12.1 0.0 1.1 8.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain Spore_IV_A PF09547.10 OAP57288.1 - 0.15 11.0 0.3 0.34 9.8 0.0 1.7 2 0 0 2 2 2 0 Stage IV sporulation protein A (spore_IV_A) AAA_23 PF13476.6 OAP57288.1 - 0.33 11.4 0.0 0.33 11.4 0.0 3.4 2 1 0 2 2 1 0 AAA domain DUF87 PF01935.17 OAP57288.1 - 3.6 7.6 7.4 2.1 8.4 0.0 3.2 3 0 0 3 3 3 0 Helicase HerA, central domain Oxidored-like PF09791.9 OAP57289.1 - 4.2e-24 83.9 4.9 8.5e-24 83.0 4.9 1.5 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal DUF5522 PF17653.1 OAP57289.1 - 0.06 13.3 3.1 0.16 11.9 3.1 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5522) SPT6_acidic PF14632.6 OAP57289.1 - 0.23 12.1 2.6 0.7 10.5 0.2 2.3 2 0 0 2 2 2 0 Acidic N-terminal SPT6 Glyoxalase PF00903.25 OAP57290.1 - 3.1e-06 27.4 0.0 6.8e-06 26.3 0.0 1.6 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 OAP57290.1 - 0.016 15.5 0.0 0.21 11.9 0.0 2.3 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 OAP57290.1 - 0.025 14.5 0.0 7.1 6.6 0.0 2.1 2 0 0 2 2 2 0 Glyoxalase-like domain DUF2388 PF09498.10 OAP57290.1 - 0.11 12.5 0.2 0.2 11.6 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2388) GLTT PF01744.20 OAP57291.1 - 0.23 11.3 0.7 0.49 10.2 0.7 1.6 1 0 0 1 1 1 0 GLTT repeat (6 copies) DUF2457 PF10446.9 OAP57292.1 - 0.44 9.6 4.6 8.7 5.4 5.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) MFS_1 PF07690.16 OAP57293.1 - 2.3e-14 53.1 32.6 2.3e-14 53.1 32.6 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAP57293.1 - 3.4e-07 29.5 11.0 3.4e-07 29.5 11.0 2.5 3 0 0 3 3 3 1 Sugar (and other) transporter Fungal_trans PF04082.18 OAP57294.1 - 3.2e-27 95.2 0.2 6.6e-27 94.2 0.1 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain FAD_binding_3 PF01494.19 OAP57295.1 - 4.4e-19 68.9 0.1 2.4e-18 66.5 0.1 1.9 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAP57295.1 - 2.5e-10 40.5 5.1 0.00034 20.3 0.0 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAP57295.1 - 8.1e-07 28.6 2.8 8e-05 22.0 0.4 2.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAP57295.1 - 8.5e-07 28.4 1.1 5.7e-06 25.7 0.9 2.0 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 OAP57295.1 - 2.6e-06 27.6 0.6 3.1e-05 24.1 0.2 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 OAP57295.1 - 5.2e-05 22.1 0.9 0.0003 19.6 0.5 2.1 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 OAP57295.1 - 8.4e-05 22.1 2.2 0.00018 21.0 2.2 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 OAP57295.1 - 0.0002 20.7 0.3 0.00062 19.1 0.3 1.8 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 OAP57295.1 - 0.00039 19.6 0.6 0.079 12.0 0.0 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox PF00070.27 OAP57295.1 - 0.00069 20.1 0.4 0.0046 17.5 0.3 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OAP57295.1 - 0.005 16.0 2.3 0.0051 15.9 1.1 1.5 2 0 0 2 2 2 1 Glucose inhibited division protein A Trp_halogenase PF04820.14 OAP57295.1 - 0.0057 15.6 3.5 0.024 13.5 0.9 2.5 2 1 1 3 3 3 1 Tryptophan halogenase Pyr_redox_3 PF13738.6 OAP57295.1 - 0.029 13.6 0.2 0.055 12.7 0.2 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 OAP57295.1 - 0.04 12.4 0.4 0.056 11.9 0.4 1.1 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like Amino_oxidase PF01593.24 OAP57295.1 - 0.085 12.1 0.2 5.9 6.1 0.0 2.3 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase CbiA PF01656.23 OAP57295.1 - 0.099 12.7 0.0 0.12 12.4 0.0 1.3 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain 3HCDH_N PF02737.18 OAP57295.1 - 0.13 12.1 0.3 0.22 11.4 0.3 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.6 OAP57295.1 - 2.5 8.1 4.0 11 6.0 0.1 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 OAP57296.1 - 2.2e-89 300.2 0.0 2.6e-89 299.9 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAP57296.1 - 0.00016 21.4 0.0 0.22 11.1 0.1 3.0 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAP57296.1 - 0.00058 19.2 0.0 0.0014 17.9 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAP57296.1 - 0.0065 15.6 0.1 0.033 13.3 0.1 1.9 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 OAP57296.1 - 0.014 15.6 0.1 0.029 14.6 0.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 OAP57296.1 - 0.026 13.8 0.0 0.049 12.9 0.0 1.5 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 OAP57296.1 - 0.031 13.5 0.1 0.046 13.0 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OAP57296.1 - 0.047 12.8 0.1 0.07 12.2 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Glyoxalase PF00903.25 OAP57297.1 - 3.7e-12 46.5 4.2 3.8e-11 43.3 1.9 2.4 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily p450 PF00067.22 OAP57298.1 - 2.6e-55 188.0 0.0 3.2e-55 187.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.25 OAP57299.1 - 7.9e-37 126.6 0.1 1e-36 126.2 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP57299.1 - 3.2e-35 121.8 0.1 4.9e-35 121.2 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP57299.1 - 2.2e-11 44.0 2.2 1.6e-09 38.0 2.2 2.1 1 1 0 1 1 1 1 KR domain Pyr_redox PF00070.27 OAP57299.1 - 0.0042 17.6 0.1 0.041 14.4 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 OAP57299.1 - 0.024 13.9 0.0 0.043 13.1 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GDP_Man_Dehyd PF16363.5 OAP57299.1 - 0.024 14.0 0.0 0.12 11.7 0.0 1.9 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Glyco_tran_WecB PF03808.13 OAP57299.1 - 0.028 14.4 0.2 3.2 7.7 0.0 2.5 2 1 1 3 3 3 0 Glycosyl transferase WecB/TagA/CpsF family DUF1776 PF08643.10 OAP57299.1 - 0.033 13.5 0.1 0.049 13.0 0.1 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) FAD_binding_3 PF01494.19 OAP57299.1 - 0.035 13.4 0.1 0.071 12.3 0.1 1.5 1 0 0 1 1 1 0 FAD binding domain Polysacc_synt_2 PF02719.15 OAP57299.1 - 0.038 13.1 0.0 0.072 12.2 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein ADH_zinc_N PF00107.26 OAP57299.1 - 0.045 13.7 0.3 0.14 12.2 0.1 1.8 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Epimerase PF01370.21 OAP57299.1 - 0.059 12.8 0.1 0.13 11.7 0.1 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family ECH_1 PF00378.20 OAP57300.1 - 2.3e-41 141.8 0.0 2.8e-41 141.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAP57300.1 - 6.4e-21 75.2 0.0 7.8e-21 74.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Lipase_3 PF01764.25 OAP57300.1 - 0.1 12.5 0.0 0.26 11.1 0.0 1.7 1 0 0 1 1 1 0 Lipase (class 3) UPF0160 PF03690.13 OAP57301.1 - 2.2e-127 425.1 0.0 2.5e-127 424.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) L_biotic_typeA PF04604.13 OAP57301.1 - 0.12 12.2 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Type-A lantibiotic UB2H PF14814.6 OAP57301.1 - 0.15 12.1 0.0 0.55 10.3 0.0 2.0 1 0 0 1 1 1 0 Bifunctional transglycosylase second domain ICE2 PF08426.10 OAP57302.1 - 1.1e-143 479.3 7.3 1.2e-143 479.1 7.3 1.0 1 0 0 1 1 1 1 ICE2 Serinc PF03348.15 OAP57302.1 - 1.2 8.0 8.3 6 5.7 0.0 2.6 3 0 0 3 3 3 0 Serine incorporator (Serinc) Endosulfine PF04667.17 OAP57303.1 - 1.5e-29 101.9 0.2 2.9e-29 101.0 0.2 1.5 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region DUF1286 PF06939.11 OAP57303.1 - 0.25 11.6 0.1 0.43 10.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1286) RNA_Me_trans PF04252.13 OAP57304.1 - 2.4e-77 259.1 0.0 2.8e-77 258.8 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase Fungal_trans_2 PF11951.8 OAP57305.1 - 5.9e-07 28.6 0.5 9.5e-07 28.0 0.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pribosyltran PF00156.27 OAP57306.1 - 1.4e-06 27.9 0.0 2.4e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Atx10homo_assoc PF09759.9 OAP57307.1 - 0.1 12.6 0.2 0.27 11.3 0.2 1.7 1 0 0 1 1 1 0 Spinocerebellar ataxia type 10 protein domain Apt1 PF10351.9 OAP57307.1 - 0.2 10.5 0.7 0.3 9.9 0.7 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain zf-C2H2 PF00096.26 OAP57308.1 - 1.3e-19 69.5 26.4 0.0002 21.6 0.1 5.8 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAP57308.1 - 2.5e-11 43.4 24.5 0.039 14.8 0.1 5.9 5 0 0 5 5 5 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OAP57308.1 - 1.6e-08 34.6 34.0 0.0065 16.9 0.3 6.0 6 0 0 6 6 5 5 Zinc-finger double domain zf_UBZ PF18439.1 OAP57308.1 - 2.3e-05 23.9 5.8 1.1 8.9 0.1 4.5 4 0 0 4 4 4 2 Ubiquitin-Binding Zinc Finger zf-C2H2_jaz PF12171.8 OAP57308.1 - 0.00026 21.2 5.4 0.28 11.5 0.0 4.2 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 OAP57308.1 - 0.001 19.0 16.2 0.063 13.3 0.1 5.3 5 0 0 5 5 5 2 C2H2-type zinc finger XPA_N PF01286.18 OAP57308.1 - 0.02 14.9 6.2 8.9 6.5 0.2 4.3 4 0 0 4 4 4 0 XPA protein N-terminal zf-Di19 PF05605.12 OAP57308.1 - 0.026 14.8 2.5 0.026 14.8 2.5 4.8 2 1 2 5 5 5 0 Drought induced 19 protein (Di19), zinc-binding IBR PF01485.21 OAP57308.1 - 0.028 14.6 19.1 0.14 12.4 4.8 3.3 1 1 2 3 3 3 0 IBR domain, a half RING-finger domain Zn_ribbon_SprT PF17283.2 OAP57308.1 - 0.04 13.8 13.1 0.037 13.9 2.4 3.8 3 0 0 3 3 3 0 SprT-like zinc ribbon domain C1_4 PF07975.12 OAP57308.1 - 0.044 14.0 0.5 0.044 14.0 0.5 3.3 2 1 1 3 3 3 0 TFIIH C1-like domain zf-C2H2_9 PF16293.5 OAP57308.1 - 0.049 13.5 0.8 4.5 7.2 0.1 2.7 1 1 1 2 2 2 0 C2H2 type zinc-finger (1 copy) zinc_ribbon_9 PF14369.6 OAP57308.1 - 0.25 11.7 6.3 17 5.8 0.1 4.5 4 0 0 4 4 4 0 zinc-ribbon TF_Zn_Ribbon PF08271.12 OAP57308.1 - 0.26 10.8 4.8 1 8.9 0.2 3.2 3 0 0 3 3 3 0 TFIIB zinc-binding zinc_ribbon_4 PF13717.6 OAP57308.1 - 0.38 10.7 16.0 0.15 12.0 3.5 4.4 4 2 0 4 4 4 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 OAP57308.1 - 0.41 10.8 22.1 0.9 9.7 3.0 4.2 2 1 3 5 5 5 0 Zinc ribbon domain zf-LYAR PF08790.11 OAP57308.1 - 2.1 8.3 12.2 24 4.9 0.1 4.3 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger zf-C2H2_2 PF12756.7 OAP57308.1 - 2.7 8.4 0.0 2.7 8.4 0.0 4.4 2 1 2 4 4 3 0 C2H2 type zinc-finger (2 copies) TRAF6_Z2 PF18048.1 OAP57308.1 - 6.8 6.9 16.2 3.6 7.8 0.1 3.8 3 0 0 3 3 3 0 TNF receptor-associated factor 6 zinc finger 2 HypA PF01155.19 OAP57308.1 - 7 6.7 15.4 0.73 9.9 0.3 3.4 1 1 1 2 2 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Ion_trans PF00520.31 OAP57309.1 - 0.00077 18.8 17.8 0.00077 18.8 17.8 1.8 2 1 0 2 2 2 1 Ion transport protein PKD_channel PF08016.12 OAP57309.1 - 0.0045 15.7 5.7 0.032 12.9 0.1 2.3 1 1 1 2 2 2 2 Polycystin cation channel DUF1989 PF09347.10 OAP57310.1 - 1.1e-28 100.0 0.0 2.5e-28 98.8 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF1989) Rhomboid PF01694.22 OAP57311.1 - 5.1e-33 114.2 10.5 5.1e-33 114.2 10.5 1.8 2 0 0 2 2 2 1 Rhomboid family VKOR PF07884.14 OAP57311.1 - 1.1 9.4 6.3 0.25 11.5 0.2 2.6 2 0 0 2 2 2 0 Vitamin K epoxide reductase family SPT_ssu-like PF11779.8 OAP57312.1 - 3e-15 55.5 0.8 5.7e-15 54.7 0.8 1.5 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like DUF2953 PF11167.8 OAP57312.1 - 0.02 15.0 0.5 0.047 13.8 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2953) UBM PF14377.6 OAP57313.1 - 0.0015 18.0 0.3 0.0015 18.0 0.3 2.3 2 0 0 2 2 2 1 Ubiquitin binding region AMP-binding PF00501.28 OAP57314.1 - 2.1e-52 178.1 0.0 5.3e-52 176.8 0.0 1.6 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAP57314.1 - 1.1e-07 32.7 0.0 2.7e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain VitD-bind_III PF09164.10 OAP57314.1 - 0.2 11.7 0.0 0.5 10.4 0.0 1.6 1 0 0 1 1 1 0 Vitamin D binding protein, domain III DASH_Dad3 PF08656.10 OAP57315.1 - 2e-23 82.2 0.1 5e-23 81.0 0.1 1.6 1 1 0 1 1 1 1 DASH complex subunit Dad3 Ribosomal_S5_C PF03719.15 OAP57316.1 - 2.1e-23 81.5 0.0 6.6e-23 80.0 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 OAP57316.1 - 1e-17 63.9 0.3 5.3e-17 61.6 0.1 2.2 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain PTPRCAP PF15713.5 OAP57316.1 - 0.037 14.3 0.1 0.071 13.4 0.1 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated LZ_Tnp_IS481 PF13011.6 OAP57316.1 - 0.6 10.7 2.7 3.2 8.3 0.1 2.8 3 0 0 3 3 3 0 leucine-zipper of insertion element IS481 PRMT5_TIM PF17285.2 OAP57317.1 - 3.5e-70 236.1 0.0 5e-70 235.6 0.0 1.2 1 0 0 1 1 1 1 PRMT5 TIM barrel domain PRMT5 PF05185.16 OAP57317.1 - 2.8e-65 219.4 0.0 3.4e-48 163.8 0.0 2.3 2 0 0 2 2 2 2 PRMT5 arginine-N-methyltransferase PRMT5_C PF17286.2 OAP57317.1 - 6.1e-57 192.3 0.0 2.2e-56 190.5 0.0 2.0 1 1 0 1 1 1 1 PRMT5 oligomerisation domain GDPD PF03009.17 OAP57318.1 - 1.8e-75 254.0 0.0 3.4e-75 253.1 0.0 1.5 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.7 OAP57318.1 - 6.6e-31 106.7 0.0 6.5e-19 68.3 0.0 3.6 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAP57318.1 - 7.8e-29 99.7 2.4 4e-12 46.4 0.0 5.2 5 0 0 5 5 5 3 Ankyrin repeats (many copies) SPX PF03105.19 OAP57318.1 - 2e-22 80.7 10.8 6.9e-11 42.7 0.1 3.9 2 1 2 4 4 4 3 SPX domain Ank_3 PF13606.6 OAP57318.1 - 1.7e-20 70.9 3.3 1.8e-05 24.8 0.0 7.3 7 0 0 7 7 7 4 Ankyrin repeat Ank PF00023.30 OAP57318.1 - 1.1e-18 66.8 4.9 0.00024 21.4 0.0 6.1 4 1 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 OAP57318.1 - 5.4e-17 61.6 1.1 2.5e-07 30.9 0.0 6.0 4 1 3 7 7 7 5 Ankyrin repeats (many copies) Dynamitin PF04912.14 OAP57318.1 - 0.095 12.0 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Dynamitin Pkinase PF00069.25 OAP57319.1 - 2.7e-75 253.1 0.0 5.7e-75 252.1 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP57319.1 - 1.6e-31 109.5 0.0 1e-22 80.7 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 OAP57319.1 - 4.8e-07 29.4 0.1 0.59 9.4 0.0 3.1 3 0 0 3 3 3 3 Kinase-like Pkinase_fungal PF17667.1 OAP57319.1 - 0.02 13.7 0.0 0.033 13.0 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 OAP57319.1 - 0.024 14.0 0.0 0.041 13.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OAP57319.1 - 0.15 11.9 0.0 2.3 8.1 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Vps4_C PF09336.10 OAP57320.1 - 0.016 15.2 0.0 0.048 13.7 0.0 1.8 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain His_Phos_2 PF00328.22 OAP57321.1 - 3.8e-10 39.7 0.0 9e-10 38.4 0.0 1.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PDGLE PF13190.6 OAP57321.1 - 0.096 12.6 0.1 0.79 9.7 0.0 2.3 2 0 0 2 2 2 0 PDGLE domain TRF PF08558.10 OAP57322.1 - 4.6e-46 157.4 0.0 2.5e-45 154.9 0.0 2.0 2 1 0 2 2 2 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.31 OAP57322.1 - 0.00013 22.1 0.1 0.0015 18.7 0.0 2.4 2 0 0 2 2 2 1 Myb-like DNA-binding domain HTH_32 PF13565.6 OAP57322.1 - 0.64 10.7 7.4 22 5.8 0.3 4.0 4 0 0 4 4 4 0 Homeodomain-like domain TFIID_30kDa PF03540.13 OAP57323.1 - 6.8e-23 80.4 0.1 1.1e-22 79.7 0.1 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit FoP_duplication PF13865.6 OAP57323.1 - 1.9 9.1 13.2 4.6 7.9 11.4 2.4 2 1 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 Ribosomal_S19 PF00203.21 OAP57324.1 - 1.2e-23 82.7 0.0 1.4e-23 82.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 Ras PF00071.22 OAP57325.1 - 2e-56 190.0 0.1 2.6e-56 189.7 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAP57325.1 - 1.5e-36 125.2 0.1 2.3e-36 124.7 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAP57325.1 - 1.6e-17 63.5 0.1 1.9e-17 63.3 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OAP57325.1 - 1.2e-06 28.2 0.0 6e-06 25.9 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 OAP57325.1 - 3.8e-06 26.5 0.0 5.1e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 OAP57325.1 - 3.9e-06 26.9 0.0 6.1e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OAP57325.1 - 1.1e-05 24.9 0.1 1.4e-05 24.6 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 OAP57325.1 - 0.00076 19.4 0.0 0.59 10.0 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase AAA_7 PF12775.7 OAP57325.1 - 0.066 12.7 0.0 0.18 11.3 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region TIR_2 PF13676.6 OAP57325.1 - 0.089 13.4 0.0 0.15 12.6 0.0 1.4 1 0 0 1 1 1 0 TIR domain PBP PF01161.20 OAP57326.1 - 5e-14 52.8 0.2 6.7e-14 52.3 0.2 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein PPR_2 PF13041.6 OAP57327.1 - 2.2e-45 152.6 4.8 7.6e-11 42.0 0.0 11.7 9 2 2 11 11 11 8 PPR repeat family PPR_3 PF13812.6 OAP57327.1 - 2.2e-29 101.3 7.2 0.0009 19.3 0.0 12.2 10 3 3 13 13 13 6 Pentatricopeptide repeat domain PPR PF01535.20 OAP57327.1 - 6.2e-23 79.4 11.3 0.0014 18.7 0.1 12.9 14 1 0 14 14 14 4 PPR repeat PPR_1 PF12854.7 OAP57327.1 - 2e-17 62.6 0.0 1e-05 25.1 0.0 8.3 8 0 0 8 8 8 2 PPR repeat PPR_long PF17177.4 OAP57327.1 - 7.4e-17 61.4 5.3 5.2e-07 29.2 0.0 5.5 3 1 2 5 5 5 4 Pentacotripeptide-repeat region of PRORP RPM2 PF08579.11 OAP57327.1 - 0.0016 18.8 0.0 1.5 9.3 0.0 4.0 4 0 0 4 4 4 1 Mitochondrial ribonuclease P subunit (RPM2) BTAD PF03704.17 OAP57327.1 - 0.026 15.0 6.5 2.8 8.4 0.0 3.9 3 1 1 4 4 4 0 Bacterial transcriptional activator domain DEP PF00610.21 OAP57327.1 - 0.056 13.5 0.1 27 4.9 0.0 3.3 3 0 0 3 3 3 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PNP_phzG_C PF10590.9 OAP57328.1 - 2.2e-21 75.7 1.7 3.4e-21 75.0 1.0 1.8 2 0 0 2 2 2 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Putative_PNPOx PF01243.20 OAP57328.1 - 4.6e-16 58.8 0.0 7.9e-16 58.0 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxase_2 PF12766.7 OAP57328.1 - 0.0058 17.2 0.1 0.015 15.9 0.1 1.8 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase EF-hand_1 PF00036.32 OAP57329.1 - 6.4e-41 134.9 8.3 5.6e-10 38.0 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 OAP57329.1 - 8.3e-32 109.5 6.1 1.8e-15 57.2 0.6 2.3 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OAP57329.1 - 4.3e-31 104.2 5.6 1.3e-08 34.1 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 OAP57329.1 - 1.5e-29 101.6 10.1 1.2e-13 50.7 0.4 4.0 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 OAP57329.1 - 1e-25 88.0 13.1 1.1e-07 31.1 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 OAP57329.1 - 4.5e-16 58.9 0.3 1.5e-09 38.0 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 OAP57329.1 - 1.8e-09 37.5 3.4 7.6e-05 22.6 0.3 2.1 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_11 PF08976.11 OAP57329.1 - 1e-08 35.9 0.2 0.00059 20.7 0.1 2.1 1 1 1 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 OAP57329.1 - 2.9e-07 30.8 0.4 0.0066 16.8 0.1 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.13 OAP57329.1 - 1.2e-05 25.2 0.1 0.082 13.0 0.0 2.5 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0154) EF-hand_14 PF17959.1 OAP57329.1 - 4.4e-05 23.7 0.5 0.36 11.2 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain Toprim_2 PF13155.6 OAP57329.1 - 0.00083 19.7 0.7 0.21 12.0 0.0 2.4 1 1 1 2 2 2 1 Toprim-like TerB PF05099.13 OAP57329.1 - 0.0012 18.8 0.6 0.14 12.1 0.1 2.6 1 1 0 2 2 2 1 Tellurite resistance protein TerB SurA_N_3 PF13624.6 OAP57329.1 - 0.0013 18.6 1.4 0.28 10.9 0.2 2.1 1 1 1 2 2 2 2 SurA N-terminal domain FGAR-AT_linker PF18072.1 OAP57329.1 - 0.0013 19.2 0.0 0.25 11.9 0.0 2.6 2 1 0 2 2 2 1 Formylglycinamide ribonucleotide amidotransferase linker domain SurA_N_2 PF13623.6 OAP57329.1 - 0.0034 17.3 2.0 0.3 10.9 0.5 2.3 1 1 1 2 2 2 1 SurA N-terminal domain RNA_pol_Rpb4 PF03874.16 OAP57329.1 - 0.0039 17.5 1.1 1.9 8.8 0.3 2.7 3 0 0 3 3 2 1 RNA polymerase Rpb4 DUF3349 PF11829.8 OAP57329.1 - 0.0048 17.7 0.4 1.4 9.7 0.1 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3349) DUF5580 PF17743.1 OAP57329.1 - 0.0065 15.1 0.0 0.0082 14.7 0.0 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5580) PMBR PF09373.10 OAP57329.1 - 0.011 15.8 0.1 50 4.3 0.0 3.9 4 0 0 4 4 3 0 Pseudomurein-binding repeat Caleosin PF05042.13 OAP57329.1 - 0.013 15.4 1.7 13 5.7 0.3 3.5 1 1 3 4 4 4 0 Caleosin related protein DUF1002 PF06207.11 OAP57329.1 - 0.038 13.5 2.0 2.8 7.4 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1002) FlgD PF03963.14 OAP57329.1 - 0.045 14.1 1.9 1.7 9.0 0.9 2.5 2 1 0 2 2 2 0 Flagellar hook capping protein - N-terminal region VbhA PF18495.1 OAP57329.1 - 0.049 13.5 0.3 54 3.8 0.0 4.2 4 1 0 4 4 4 0 Antitoxin VbhA Syntaxin PF00804.25 OAP57329.1 - 0.051 13.2 0.6 1.9 8.1 0.2 2.1 1 1 0 2 2 2 0 Syntaxin YqeY PF09424.10 OAP57329.1 - 0.053 13.6 0.2 0.73 9.9 0.1 2.1 1 1 1 2 2 2 0 Yqey-like protein Maf PF02545.14 OAP57329.1 - 0.053 13.4 0.2 0.61 9.9 0.0 2.1 1 1 0 2 2 2 0 Maf-like protein DUF1296 PF06972.11 OAP57329.1 - 0.055 13.6 1.9 0.78 9.9 0.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1296) DUF1456 PF07308.13 OAP57329.1 - 0.089 13.1 0.6 4.3 7.8 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1456) DUF4497 PF14924.6 OAP57329.1 - 0.089 13.3 0.1 3.9 8.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4497) MotA_activ PF09114.10 OAP57329.1 - 0.12 12.5 0.1 16 5.7 0.0 2.2 1 1 1 2 2 2 0 Transcription factor MotA, activation domain EF-hand_10 PF14788.6 OAP57329.1 - 0.89 9.5 7.1 0.39 10.6 0.6 3.5 2 2 3 5 5 5 0 EF hand DUF4337 PF14235.6 OAP57331.1 - 2 8.5 4.2 12 6.0 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) TPR_12 PF13424.6 OAP57332.1 - 3.8e-27 94.4 1.6 1.7e-08 34.6 0.0 6.9 3 1 5 8 8 8 6 Tetratricopeptide repeat TPR_10 PF13374.6 OAP57332.1 - 1.8e-22 78.5 5.8 0.00038 20.2 0.0 8.6 9 0 0 9 9 9 4 Tetratricopeptide repeat NB-ARC PF00931.22 OAP57332.1 - 7.8e-10 38.4 0.0 9e-09 34.9 0.0 2.4 2 1 0 2 2 2 1 NB-ARC domain TPR_MalT PF17874.1 OAP57332.1 - 4.9e-08 32.7 0.3 8.5e-06 25.4 0.0 2.7 2 1 0 3 3 3 1 MalT-like TPR region TPR_19 PF14559.6 OAP57332.1 - 1.5e-05 25.4 0.0 0.65 10.5 0.0 4.3 2 1 1 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 OAP57332.1 - 5e-05 23.0 0.3 0.076 13.1 0.0 4.7 5 0 0 5 5 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 OAP57332.1 - 0.00016 22.3 2.3 0.16 12.7 0.0 5.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.17 OAP57332.1 - 0.00066 19.6 2.2 0.28 11.4 0.1 4.9 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 OAP57332.1 - 0.00067 20.3 2.6 31 5.8 0.0 7.0 7 2 2 9 9 6 0 Tetratricopeptide repeat TPR_8 PF13181.6 OAP57332.1 - 0.00082 19.4 2.9 17 5.9 0.0 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat PPR PF01535.20 OAP57332.1 - 0.0011 19.1 0.1 0.087 13.1 0.1 3.8 4 0 0 4 4 3 1 PPR repeat TPR_20 PF14561.6 OAP57332.1 - 0.0014 18.9 0.0 0.84 10.0 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 OAP57332.1 - 0.0025 18.1 0.5 0.072 13.5 0.0 3.6 5 0 0 5 5 3 1 Tetratricopeptide repeat AAA_16 PF13191.6 OAP57332.1 - 0.0039 17.6 0.4 0.19 12.1 0.0 2.7 1 1 0 2 2 2 1 AAA ATPase domain HET-S PF17108.5 OAP57332.1 - 0.015 15.1 0.6 0.031 14.0 0.6 1.6 1 0 0 1 1 1 0 N-terminal small S protein of HET, non-prionic ATPase_2 PF01637.18 OAP57332.1 - 0.025 14.5 0.0 0.051 13.5 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea RPN7 PF10602.9 OAP57332.1 - 0.048 13.4 0.1 3.3 7.4 0.0 3.0 3 1 1 4 4 4 0 26S proteasome subunit RPN7 AAA_22 PF13401.6 OAP57332.1 - 0.12 12.6 0.0 0.78 10.0 0.0 2.3 1 1 0 1 1 1 0 AAA domain TPR_1 PF00515.28 OAP57332.1 - 0.2 11.6 1.9 34 4.5 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 OAP57332.1 - 0.8 10.5 12.0 6.1 7.8 0.0 6.0 7 0 0 7 7 5 0 Tetratricopeptide repeat p450 PF00067.22 OAP57333.1 - 2.3e-60 204.7 0.0 3e-60 204.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HeLo PF14479.6 OAP57334.1 - 2.9e-50 171.0 2.1 3.5e-50 170.7 1.7 1.3 1 1 0 1 1 1 1 Prion-inhibition and propagation HET-s_218-289 PF11558.8 OAP57334.1 - 0.087 12.9 1.1 0.47 10.5 1.1 2.3 1 1 0 1 1 1 0 Het-s 218-289 F1F0-ATPsyn_F PF10791.9 OAP57335.1 - 9.2e-38 128.6 0.1 1.2e-37 128.2 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi WRW PF10206.9 OAP57335.1 - 0.043 14.2 0.2 0.069 13.5 0.2 1.3 1 0 0 1 1 1 0 Mitochondrial F1F0-ATP synthase, subunit f PAM2 PF07145.15 OAP57337.1 - 0.027 14.1 0.2 0.14 11.9 0.0 2.3 2 0 0 2 2 2 0 Ataxin-2 C-terminal region SH3_9 PF14604.6 OAP57338.1 - 1.8e-05 24.5 0.2 5e-05 23.1 0.2 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 OAP57338.1 - 0.00027 20.5 1.2 0.00032 20.2 0.1 1.7 2 0 0 2 2 2 1 SH3 domain Mid2 PF04478.12 OAP57338.1 - 0.00029 20.7 0.2 0.00056 19.8 0.2 1.3 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor EphA2_TM PF14575.6 OAP57338.1 - 0.00043 21.1 0.0 0.00086 20.1 0.0 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Adeno_E3_CR2 PF02439.15 OAP57338.1 - 0.0018 18.0 2.0 0.0033 17.2 2.0 1.3 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Insulin_TMD PF17870.1 OAP57338.1 - 0.002 18.2 0.7 0.004 17.2 0.7 1.4 1 0 0 1 1 1 1 Insulin receptor trans-membrane segment DUF4690 PF15756.5 OAP57338.1 - 0.0058 17.2 0.2 0.019 15.6 0.2 1.9 1 0 0 1 1 1 1 Small Novel Rich in Cartilage CYYR1 PF10873.8 OAP57338.1 - 0.0062 17.0 1.7 0.0062 17.0 1.7 2.3 3 1 0 3 3 2 1 Cysteine and tyrosine-rich protein 1 Stevor PF17410.2 OAP57338.1 - 0.0092 15.6 0.0 0.018 14.6 0.0 1.4 1 0 0 1 1 1 1 Subtelomeric Variable Open Reading frame TMEM154 PF15102.6 OAP57338.1 - 0.015 15.2 0.0 0.033 14.1 0.0 1.5 1 0 0 1 1 1 0 TMEM154 protein family Cadherin_C_2 PF16492.5 OAP57338.1 - 0.058 14.1 0.0 0.15 12.8 0.0 1.7 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal CD34_antigen PF06365.12 OAP57338.1 - 0.083 12.5 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 CD34/Podocalyxin family Syndecan PF01034.20 OAP57338.1 - 0.12 12.3 0.8 0.23 11.4 0.8 1.3 1 0 0 1 1 1 0 Syndecan domain Arylesterase PF01731.20 OAP57339.1 - 0.056 13.6 3.8 53 4.1 0.0 4.4 3 2 1 4 4 4 0 Arylesterase UvdE PF03851.14 OAP57341.1 - 7.2e-108 360.0 0.0 9.3e-108 359.6 0.0 1.1 1 0 0 1 1 1 1 UV-endonuclease UvdE SPT2 PF08243.11 OAP57341.1 - 3.8 8.1 8.1 2.1 8.9 1.1 2.8 2 0 0 2 2 2 0 SPT2 chromatin protein ADH_N PF08240.12 OAP57342.1 - 1.6e-26 92.3 4.9 2.6e-26 91.6 4.9 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAP57342.1 - 2.7e-14 53.3 0.0 7.5e-14 51.8 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 OAP57342.1 - 0.001 18.4 0.0 0.0016 17.8 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 OAP57342.1 - 0.012 15.0 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 OAP57342.1 - 0.057 13.3 0.0 0.22 11.4 0.0 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 OAP57342.1 - 0.095 13.1 0.0 0.19 12.2 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding ABC_tran PF00005.27 OAP57344.1 - 8e-23 81.5 0.0 3.4e-11 43.8 0.0 3.0 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 OAP57344.1 - 3.2e-08 33.8 0.2 0.008 16.0 0.0 3.0 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 OAP57344.1 - 2.6e-05 24.4 0.0 0.011 15.9 0.0 2.6 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.6 OAP57344.1 - 0.011 16.0 0.0 0.36 11.1 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_29 PF13555.6 OAP57344.1 - 0.027 14.2 0.1 0.054 13.2 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 OAP57344.1 - 0.061 13.7 0.2 0.24 11.8 0.0 2.1 2 1 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.6 OAP57344.1 - 0.08 13.4 0.2 0.13 12.8 0.2 1.2 1 0 0 1 1 1 0 AAA domain Metallophos PF00149.28 OAP57345.1 - 1.4e-33 117.1 0.0 3.3e-29 102.8 0.0 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 OAP57345.1 - 0.12 12.0 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain Smg4_UPF3 PF03467.15 OAP57346.1 - 7e-41 140.1 0.0 7e-41 140.1 0.0 3.1 3 1 0 3 3 3 1 Smg-4/UPF3 family RRM_1 PF00076.22 OAP57346.1 - 1.1e-08 34.7 0.3 3.1e-07 30.1 0.0 2.9 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Mre11_DNA_bind PF04152.14 OAP57347.1 - 4.4e-49 167.1 2.1 4.4e-49 167.1 2.1 2.0 3 0 0 3 3 3 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 OAP57347.1 - 1.9e-14 54.6 3.5 3.2e-14 53.9 3.5 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OAP57347.1 - 0.00041 20.6 0.5 0.003 17.8 0.5 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain PBP1_TM PF14812.6 OAP57347.1 - 0.11 12.8 22.2 0.044 14.2 5.3 4.6 4 0 0 4 4 4 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4275 PF14101.6 OAP57348.1 - 0.013 15.7 0.1 0.024 14.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4275) Gpr1_Fun34_YaaH PF01184.19 OAP57349.1 - 7.6e-38 130.2 27.0 9.5e-38 129.9 27.0 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Bunya_G2 PF03563.13 OAP57349.1 - 0.86 8.8 2.9 1.2 8.3 2.9 1.1 1 0 0 1 1 1 0 Bunyavirus glycoprotein G2 F-box-like PF12937.7 OAP57351.1 - 4.2e-10 39.3 0.2 1.8e-09 37.4 0.1 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 OAP57351.1 - 1.8e-09 37.3 0.1 3.4e-09 36.3 0.1 1.5 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 OAP57351.1 - 0.091 12.6 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 F-box UIM PF02809.20 OAP57351.1 - 2.2 8.4 16.6 0.31 11.1 3.0 3.6 3 0 0 3 3 3 0 Ubiquitin interaction motif NAD_binding_2 PF03446.15 OAP57352.1 - 3.3e-40 137.8 0.1 6.1e-40 137.0 0.0 1.4 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 OAP57352.1 - 2.3e-24 86.0 0.0 3.7e-24 85.3 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase OCD_Mu_crystall PF02423.15 OAP57352.1 - 0.00081 18.4 0.0 0.0012 17.8 0.0 1.2 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family F420_oxidored PF03807.17 OAP57352.1 - 0.00085 19.9 0.0 0.0021 18.6 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 OAP57352.1 - 0.016 14.5 0.0 0.032 13.6 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 OAP57352.1 - 0.03 15.1 0.0 0.063 14.1 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Shikimate_DH PF01488.20 OAP57352.1 - 0.056 13.5 0.0 0.097 12.7 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF3053 PF11254.8 OAP57352.1 - 0.1 12.2 0.1 3.4 7.2 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3053) Fungal_trans_2 PF11951.8 OAP57353.1 - 5.2e-11 42.0 0.0 1.9e-10 40.1 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Mannosyl_trans3 PF11051.8 OAP57354.1 - 9.9e-59 198.9 0.1 1.8e-35 122.7 0.0 2.1 1 1 1 2 2 2 2 Mannosyltransferase putative MAP65_ASE1 PF03999.12 OAP57355.1 - 3.2e-66 224.3 48.9 7.5e-66 223.1 40.0 3.0 1 1 0 2 2 2 2 Microtubule associated protein (MAP65/ASE1 family) Baculo_PEP_C PF04513.12 OAP57355.1 - 0.014 15.5 0.5 0.059 13.4 0.5 2.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus BLOC1_2 PF10046.9 OAP57355.1 - 0.16 12.3 5.3 9.1 6.7 0.5 3.4 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spectrin PF00435.21 OAP57355.1 - 0.24 11.9 12.1 1 9.9 1.1 4.0 3 1 0 3 3 3 0 Spectrin repeat Vps5 PF09325.10 OAP57355.1 - 1.7 8.1 8.3 8.2 5.9 0.2 3.5 4 0 0 4 4 4 0 Vps5 C terminal like VGPC1_C PF16799.5 OAP57355.1 - 4.5 7.3 7.9 9.8 6.2 0.1 3.0 3 0 0 3 3 3 0 C-terminal membrane-localisation domain of ion-channel, VCN1 Sugar_tr PF00083.24 OAP57356.1 - 1.5e-88 297.7 18.6 1.7e-88 297.5 18.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP57356.1 - 7e-25 87.7 26.7 1.1e-23 83.7 16.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 OAP57356.1 - 9.9e-05 20.9 1.7 9.9e-05 20.9 1.7 2.4 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Kinocilin PF15033.6 OAP57356.1 - 5.8 6.6 8.3 31 4.3 2.5 3.5 2 1 1 3 3 3 0 Kinocilin protein F_bP_aldolase PF01116.20 OAP57357.1 - 2.4e-79 266.7 0.0 2.8e-79 266.5 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Epimerase PF01370.21 OAP57358.1 - 7.6e-18 64.9 0.0 9.6e-18 64.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OAP57358.1 - 2.2e-10 40.0 0.0 2.9e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 OAP57358.1 - 2.5e-10 40.3 0.1 3.4e-09 36.5 0.1 2.0 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 OAP57358.1 - 3.7e-07 29.6 0.0 0.00065 19.0 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 OAP57358.1 - 1.9e-06 27.2 0.1 1.1e-05 24.7 0.1 1.9 1 1 0 1 1 1 1 RmlD substrate binding domain Ldh_1_N PF00056.23 OAP57358.1 - 0.00044 20.4 0.0 0.00074 19.6 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain DapB_N PF01113.20 OAP57358.1 - 0.1 12.7 0.0 0.18 12.0 0.0 1.5 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus DUF348 PF03990.14 OAP57358.1 - 0.18 11.5 2.0 12 5.7 0.0 2.4 2 0 0 2 2 2 0 G5-linked-Ubiquitin-like domain Polysacc_synt_2 PF02719.15 OAP57358.1 - 0.2 10.8 0.0 0.41 9.7 0.0 1.5 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein PhyH PF05721.13 OAP57359.1 - 3e-07 30.9 0.1 5.6e-07 30.0 0.1 1.4 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 OAP57359.1 - 2.5e-06 26.5 0.4 0.023 13.5 0.0 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF1479) PHZA_PHZB PF03284.13 OAP57359.1 - 0.05 13.2 0.1 0.13 11.8 0.1 1.7 1 0 0 1 1 1 0 Phenazine biosynthesis protein A/B Fungal_trans PF04082.18 OAP57360.1 - 4e-18 65.4 0.1 5.8e-18 64.9 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP57360.1 - 8.3e-08 32.2 12.2 1.9e-07 31.1 12.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 2-Hacid_dh_C PF02826.19 OAP57361.1 - 5e-53 179.1 0.0 8.2e-53 178.4 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 OAP57361.1 - 1.5e-20 73.3 0.0 1.8e-20 72.9 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 OAP57361.1 - 0.0021 18.3 0.0 0.0038 17.4 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase JAB PF01398.21 OAP57362.1 - 9.3e-30 103.0 0.0 1.8e-29 102.1 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease CSN5_C PF18323.1 OAP57362.1 - 1.6e-23 83.4 0.1 2.7e-23 82.7 0.1 1.4 1 0 0 1 1 1 1 Cop9 signalosome subunit 5 C-terminal domain Prok-JAB PF14464.6 OAP57362.1 - 1.8e-05 24.5 0.1 8e-05 22.4 0.0 2.0 2 0 0 2 2 2 1 Prokaryotic homologs of the JAB domain DUF1586 PF07625.11 OAP57362.1 - 0.055 13.5 4.8 2 8.6 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1586) DUF3763 PF12592.8 OAP57363.1 - 0.086 12.9 1.4 0.27 11.3 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3763) PX PF00787.24 OAP57364.1 - 7.7e-17 61.3 0.1 2.6e-16 59.6 0.1 1.9 1 0 0 1 1 1 1 PX domain Prefoldin_3 PF13758.6 OAP57364.1 - 0.4 10.8 2.1 0.58 10.3 0.0 2.4 3 0 0 3 3 3 0 Prefoldin subunit IBN_N PF03810.19 OAP57366.1 - 1.1e-07 31.6 0.0 7.4e-07 29.0 0.0 2.5 1 0 0 1 1 1 1 Importin-beta N-terminal domain Xpo1 PF08389.12 OAP57366.1 - 0.0009 19.3 1.0 0.26 11.4 0.0 4.7 7 1 0 7 7 7 1 Exportin 1-like protein Cse1 PF08506.10 OAP57366.1 - 0.0015 17.5 0.1 0.0033 16.3 0.1 1.5 1 0 0 1 1 1 1 Cse1 HEAT_EZ PF13513.6 OAP57366.1 - 0.49 11.0 5.4 3.2 8.4 0.1 4.3 5 0 0 5 5 5 0 HEAT-like repeat Dcc1 PF09724.9 OAP57367.1 - 2.4e-17 63.2 0.0 2e-16 60.3 0.0 2.0 1 1 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 CysG_dimeriser PF10414.9 OAP57367.1 - 0.029 14.1 1.2 3.8 7.3 0.0 2.6 2 0 0 2 2 2 0 Sirohaem synthase dimerisation region Anp1 PF03452.14 OAP57368.1 - 1.7e-113 378.4 0.0 5e-113 376.9 0.0 1.7 2 0 0 2 2 2 1 Anp1 Glyco_tranf_2_4 PF13704.6 OAP57368.1 - 0.0077 16.7 0.1 0.023 15.2 0.1 1.8 1 0 0 1 1 1 1 Glycosyl transferase family 2 Rad54_N PF08658.10 OAP57368.1 - 0.078 13.1 0.7 0.16 12.1 0.7 1.4 1 0 0 1 1 1 0 Rad54 N terminal BTB PF00651.31 OAP57369.1 - 3.2e-05 24.1 0.0 5.1e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain Aa_trans PF01490.18 OAP57370.1 - 8.5e-23 80.7 35.6 1.5e-22 79.9 35.6 1.4 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein CBF PF03914.17 OAP57371.1 - 2.6e-52 177.3 1.3 1.4e-51 174.9 1.3 2.4 1 0 0 1 1 1 1 CBF/Mak21 family CinA PF02464.17 OAP57372.1 - 0.024 14.2 0.2 0.94 9.0 0.0 2.2 2 0 0 2 2 2 0 Competence-damaged protein DUF4134 PF13572.6 OAP57372.1 - 0.17 12.2 0.5 0.37 11.1 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4134) MGC-24 PF05283.11 OAP57372.1 - 0.22 12.0 1.9 0.4 11.1 1.9 1.4 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Abhydrolase_6 PF12697.7 OAP57374.1 - 3.6e-10 40.8 15.4 7.1e-09 36.6 15.4 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAP57374.1 - 5e-07 29.6 0.1 9.1e-07 28.8 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.13 OAP57374.1 - 0.0073 16.2 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase PGA_cap PF09587.10 OAP57375.1 - 6.2e-47 160.2 0.0 2.1e-46 158.5 0.0 1.7 1 1 0 1 1 1 1 Bacterial capsule synthesis protein PGA_cap Adeno_shaft PF00608.17 OAP57375.1 - 0.19 11.6 0.0 1.7 8.6 0.0 2.2 2 0 0 2 2 2 0 Adenoviral fibre protein (repeat/shaft region) MFS_1 PF07690.16 OAP57376.1 - 1.4e-27 96.6 28.8 2.1e-27 96.0 27.3 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily ADH_N PF08240.12 OAP57377.1 - 6e-29 100.1 2.9 1.2e-28 99.2 2.9 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAP57377.1 - 1.2e-19 70.5 0.0 2e-19 69.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 OAP57377.1 - 2.1e-08 33.9 0.5 8.2e-08 32.0 0.5 1.8 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 OAP57377.1 - 0.00063 19.1 0.0 0.0012 18.2 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.6 OAP57377.1 - 0.0022 19.0 0.0 0.0043 18.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AAA PF00004.29 OAP57378.1 - 5.4e-16 59.2 0.0 1e-15 58.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_10 PF17872.1 OAP57378.1 - 2.2e-12 47.0 0.2 6.6e-12 45.4 0.2 1.8 1 0 0 1 1 1 1 AAA lid domain AAA_16 PF13191.6 OAP57378.1 - 1.3e-09 38.7 0.0 1.1e-08 35.7 0.0 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OAP57378.1 - 2.4e-09 37.6 0.0 1e-08 35.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain BAH PF01426.18 OAP57378.1 - 4.8e-05 23.2 0.0 0.00013 21.8 0.0 1.7 2 0 0 2 2 2 1 BAH domain AAA_19 PF13245.6 OAP57378.1 - 0.0036 17.6 0.0 0.0086 16.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 OAP57378.1 - 0.019 14.8 0.0 0.053 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 OAP57378.1 - 0.027 14.7 0.0 0.1 12.8 0.0 2.0 1 0 0 1 1 1 0 AAA domain PIF1 PF05970.14 OAP57378.1 - 0.029 13.6 0.0 0.045 12.9 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase AAA_18 PF13238.6 OAP57378.1 - 0.068 13.7 0.0 0.15 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 OAP57378.1 - 0.094 12.6 0.0 0.29 11.0 0.0 1.8 1 1 0 1 1 1 0 NACHT domain DUF2075 PF09848.9 OAP57378.1 - 0.14 11.4 0.0 0.24 10.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) KH_1 PF00013.29 OAP57379.1 - 0.00099 18.9 0.0 0.69 9.8 0.0 2.5 2 0 0 2 2 2 2 KH domain Prefoldin PF02996.17 OAP57380.1 - 9.1e-19 67.5 0.0 1.3e-18 67.1 0.0 1.2 1 0 0 1 1 1 1 Prefoldin subunit DUF1192 PF06698.11 OAP57380.1 - 0.0079 16.2 0.2 0.02 14.9 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1192) Snapin_Pallidin PF14712.6 OAP57380.1 - 0.016 15.7 0.9 0.11 13.0 0.4 2.1 2 0 0 2 2 2 0 Snapin/Pallidin Dynamitin PF04912.14 OAP57380.1 - 0.035 13.5 0.6 0.14 11.5 0.6 1.8 1 1 0 1 1 1 0 Dynamitin DUF1664 PF07889.12 OAP57380.1 - 0.12 12.5 0.3 1.6 8.8 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Phage_TAC_11 PF11836.8 OAP57380.1 - 0.15 12.2 2.0 0.16 12.1 0.0 2.0 3 0 0 3 3 3 0 Phage tail tube protein, GTA-gp10 WXG100 PF06013.12 OAP57380.1 - 2.9 8.2 5.4 3.3 8.0 0.0 2.9 3 1 0 3 3 3 0 Proteins of 100 residues with WXG tRNA-synt_2b PF00587.25 OAP57381.1 - 5.2e-35 121.0 0.0 7.9e-35 120.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 OAP57381.1 - 7.3e-12 45.3 0.1 1.5e-11 44.3 0.1 1.5 1 0 0 1 1 1 1 Anticodon binding domain Myb_Cef PF11831.8 OAP57383.1 - 1.6e-47 162.1 10.3 1.6e-47 162.1 10.3 3.3 3 0 0 3 3 3 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.31 OAP57383.1 - 1.6e-21 76.2 4.7 3.3e-10 40.0 0.8 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OAP57383.1 - 1.7e-20 73.0 5.0 1.6e-13 50.7 1.5 2.7 1 1 1 2 2 2 2 Myb-like DNA-binding domain Rap1_C PF11626.8 OAP57383.1 - 0.084 13.0 3.7 0.14 12.3 0.0 2.9 3 0 0 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Lactonase PF10282.9 OAP57384.1 - 4.4e-59 200.5 0.0 5.9e-59 200.1 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller PD40 PF07676.12 OAP57384.1 - 0.00097 19.0 0.0 0.12 12.4 0.0 3.2 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat Sugar_tr PF00083.24 OAP57385.1 - 9.9e-78 262.0 22.7 1.2e-77 261.8 22.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP57385.1 - 4.6e-22 78.4 20.2 4.6e-22 78.4 20.2 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF4387 PF14330.6 OAP57386.1 - 5.7e-35 119.9 0.0 1e-34 119.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4387) AtuA PF07287.11 OAP57386.1 - 2.3e-21 75.9 0.0 1.7e-20 73.1 0.0 2.0 1 1 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA Fungal_trans PF04082.18 OAP57387.1 - 8.1e-07 28.3 0.0 3.3e-06 26.3 0.0 1.9 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP57387.1 - 3.9e-06 26.9 6.6 7e-06 26.1 6.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RPAP1_N PF08621.10 OAP57387.1 - 0.091 12.5 0.1 0.21 11.4 0.1 1.5 1 0 0 1 1 1 0 RPAP1-like, N-terminal MFS_1 PF07690.16 OAP57388.1 - 1.7e-30 106.2 25.2 1.3e-25 90.1 9.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 OAP57388.1 - 6.4e-05 22.4 1.7 6.4e-05 22.4 1.7 2.6 3 0 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB EamA PF00892.20 OAP57388.1 - 0.031 14.4 0.4 0.031 14.4 0.4 3.6 3 1 0 3 3 3 0 EamA-like transporter family LapA_dom PF06305.11 OAP57388.1 - 2.5 8.0 7.1 20 5.1 1.4 2.8 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain GFA PF04828.14 OAP57389.1 - 3.5e-05 24.1 1.1 3.5e-05 24.1 1.1 1.6 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme PHD_Oberon PF07227.11 OAP57389.1 - 0.23 11.3 6.2 0.63 9.9 0.5 2.2 2 0 0 2 2 2 0 PHD - plant homeodomain finger protein Fungal_trans PF04082.18 OAP57390.1 - 7.2e-06 25.2 0.2 1.8e-05 23.9 0.2 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP57390.1 - 2.3e-05 24.4 8.8 3.7e-05 23.8 8.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_39 PF01229.17 OAP57391.1 - 9.5e-42 143.2 0.1 2e-41 142.1 0.1 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 39 GST_C PF00043.25 OAP57392.1 - 7.1e-10 39.0 0.0 1.9e-09 37.6 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 OAP57392.1 - 1.9e-08 34.5 0.0 4.5e-08 33.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OAP57392.1 - 8.5e-07 29.2 0.0 1.6e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 OAP57392.1 - 1.1e-06 29.0 0.0 3.5e-06 27.3 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAP57392.1 - 1.6e-06 28.0 0.1 3.5e-06 26.9 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OAP57392.1 - 6.7e-05 23.0 0.0 0.00014 22.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Fungal_trans PF04082.18 OAP57393.1 - 1.4e-10 40.6 0.0 4.2e-10 39.1 0.0 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP57393.1 - 5e-06 26.5 10.1 1.1e-05 25.5 10.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.24 OAP57394.1 - 9.3e-77 258.8 19.3 1.1e-76 258.6 19.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP57394.1 - 1.3e-23 83.5 23.6 1.3e-23 83.5 23.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Tmemb_18A PF09771.9 OAP57394.1 - 0.17 12.3 0.4 28 5.1 0.1 2.7 2 0 0 2 2 2 0 Transmembrane protein 188 TauD PF02668.16 OAP57395.1 - 9.2e-61 206.0 0.8 1e-60 205.8 0.8 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family SatD PF16264.5 OAP57395.1 - 0.19 11.3 0.0 0.39 10.3 0.0 1.4 1 0 0 1 1 1 0 SatD family (SatD) FMO-like PF00743.19 OAP57396.1 - 4.6e-16 58.3 1.1 4.3e-09 35.4 0.0 3.3 2 1 1 3 3 3 3 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OAP57396.1 - 3.9e-13 49.4 0.0 1.3e-12 47.7 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 OAP57396.1 - 4.9e-07 29.2 0.0 5.2e-05 22.6 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 OAP57396.1 - 0.00013 21.3 0.1 0.0065 15.8 0.0 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAP57396.1 - 0.0013 18.0 0.0 0.31 10.2 0.0 2.8 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAP57396.1 - 0.0093 15.2 0.0 0.046 13.0 0.0 1.9 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.6 OAP57396.1 - 0.01 15.8 0.0 0.16 11.9 0.0 2.7 3 0 0 3 3 3 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 OAP57396.1 - 0.16 11.0 0.0 0.27 10.3 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein adh_short_C2 PF13561.6 OAP57397.1 - 5.2e-62 209.4 0.1 6.1e-62 209.2 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP57397.1 - 1.5e-45 155.0 0.1 1.9e-45 154.7 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAP57397.1 - 1.9e-15 57.3 0.1 3.3e-15 56.5 0.1 1.4 1 0 0 1 1 1 1 KR domain TrkA_N PF02254.18 OAP57397.1 - 0.0056 16.9 0.2 0.014 15.7 0.0 1.7 2 0 0 2 2 2 1 TrkA-N domain HATPase_c PF02518.26 OAP57397.1 - 0.01 16.4 0.0 0.024 15.1 0.0 1.6 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Epimerase PF01370.21 OAP57397.1 - 0.029 13.8 0.0 0.044 13.2 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family AMP-binding PF00501.28 OAP57398.1 - 6.4e-86 288.6 0.0 8.3e-86 288.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAP57398.1 - 1.5e-15 57.9 0.0 1.4e-14 54.8 0.0 2.3 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain GST_N PF02798.20 OAP57400.1 - 2.7e-15 56.5 0.0 4.2e-15 55.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 OAP57400.1 - 1.4e-13 51.0 0.0 2.2e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OAP57400.1 - 6.7e-10 39.1 0.0 9.8e-10 38.5 0.0 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 OAP57400.1 - 2.5e-09 37.3 0.0 3.6e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAP57400.1 - 7.6e-07 29.1 0.1 1.4e-06 28.2 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OAP57400.1 - 0.00045 20.4 0.0 0.0007 19.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain HET PF06985.11 OAP57401.1 - 7.7e-25 87.9 0.0 1.4e-24 87.1 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ADH_zinc_N PF00107.26 OAP57402.1 - 6.3e-11 42.4 0.6 1.1e-10 41.6 0.6 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAP57402.1 - 5.8e-08 32.6 0.1 1.9e-07 30.9 0.1 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 OAP57402.1 - 0.035 13.6 0.4 0.079 12.4 0.3 1.8 1 1 1 2 2 2 0 short chain dehydrogenase DUF5617 PF18493.1 OAP57402.1 - 0.19 11.8 0.1 0.54 10.4 0.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF5617) Fungal_trans_2 PF11951.8 OAP57403.1 - 0.021 13.6 0.0 0.046 12.5 0.0 1.5 1 0 0 1 1 1 0 Fungal specific transcription factor domain Abhydrolase_3 PF07859.13 OAP57404.1 - 9.1e-33 113.9 0.0 1.1e-32 113.6 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 OAP57404.1 - 1.3e-12 47.3 0.0 1.9e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase 4HBT PF03061.22 OAP57405.1 - 3.5e-10 40.1 0.4 6.6e-10 39.2 0.0 1.6 2 0 0 2 2 2 1 Thioesterase superfamily 4HBT_3 PF13622.6 OAP57405.1 - 0.00033 21.0 0.2 0.0031 17.8 0.0 2.0 1 1 1 2 2 2 1 Thioesterase-like superfamily DUF4442 PF14539.6 OAP57405.1 - 0.018 15.2 0.1 0.028 14.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) OPT PF03169.15 OAP57406.1 - 9.4e-152 506.8 42.0 1.1e-151 506.6 42.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein adh_short PF00106.25 OAP57407.1 - 3.1e-23 82.2 0.0 1.6e-18 66.9 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAP57407.1 - 8.6e-13 48.4 0.0 7.6e-09 35.5 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP57407.1 - 2.6e-10 40.5 0.1 3.8e-10 40.0 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAP57407.1 - 0.00012 21.7 0.0 0.00017 21.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 OAP57407.1 - 0.14 11.2 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein adh_short PF00106.25 OAP57408.1 - 6.4e-24 84.5 0.0 9.1e-24 84.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP57408.1 - 3.7e-19 69.2 0.0 4.5e-19 68.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP57408.1 - 5.7e-06 26.4 0.0 7.7e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 KR domain NACHT PF05729.12 OAP57410.1 - 3.3e-06 27.1 0.0 9e-06 25.7 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 OAP57410.1 - 6.7e-06 26.6 1.2 9.1e-05 22.9 0.0 3.0 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 OAP57410.1 - 0.00027 21.2 0.0 0.002 18.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 OAP57410.1 - 0.007 15.6 0.0 0.13 11.5 0.0 2.6 1 1 0 1 1 1 1 NB-ARC domain AAA PF00004.29 OAP57410.1 - 0.02 15.3 0.0 0.054 13.9 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 OAP57410.1 - 0.13 12.3 0.1 24 4.9 0.0 3.1 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 OAP57410.1 - 0.18 12.4 0.0 0.47 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain SNF2_N PF00176.23 OAP57411.1 - 2.8e-67 226.9 0.2 4.1e-67 226.4 0.2 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OAP57411.1 - 7.4e-16 58.5 0.0 3.7e-15 56.2 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAP57411.1 - 1.2e-06 28.7 0.0 2.8e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 OAP57411.1 - 0.00028 20.2 0.0 0.0005 19.4 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase SWI2_SNF2 PF18766.1 OAP57411.1 - 0.1 12.2 0.0 0.46 10.1 0.0 2.0 1 1 0 1 1 1 0 SWI2/SNF2 ATPase Nop53 PF07767.11 OAP57412.1 - 3.8e-82 276.8 26.8 6.6e-82 276.0 26.8 1.4 1 1 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) Repressor_Mnt PF11423.8 OAP57412.1 - 1.9 8.3 5.3 1.1 9.1 2.4 2.0 2 0 0 2 2 2 0 Regulatory protein Mnt RSN1_7TM PF02714.15 OAP57413.1 - 7.6e-85 284.5 27.5 5.4e-83 278.5 24.6 2.5 2 0 0 2 2 2 2 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 OAP57413.1 - 6.8e-46 155.9 1.4 6.8e-46 155.9 1.4 3.2 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 OAP57413.1 - 9.6e-36 123.6 0.6 1.5e-35 123.0 0.6 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 OAP57413.1 - 8.4e-29 99.6 0.0 4.7e-28 97.2 0.0 2.1 2 0 0 2 2 2 1 Extracellular tail, of 10TM putative phosphate transporter DUF3925 PF13063.6 OAP57413.1 - 2.9 8.2 8.0 1.6 9.0 0.5 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3925) RNase_P_Rpp14 PF01900.19 OAP57415.1 - 3.6e-32 110.7 0.0 4.6e-32 110.3 0.0 1.1 1 0 0 1 1 1 1 Rpp14/Pop5 family ATP_bind_1 PF03029.17 OAP57416.1 - 5.3e-69 232.7 0.0 1.3e-68 231.4 0.0 1.6 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein MeaB PF03308.16 OAP57416.1 - 0.0032 16.5 0.2 0.0073 15.3 0.0 1.6 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 OAP57416.1 - 0.017 15.2 0.0 5 7.2 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_31 PF13614.6 OAP57416.1 - 0.026 14.4 0.0 7.4 6.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 OAP57416.1 - 0.078 12.7 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.7 OAP57416.1 - 0.15 11.0 0.0 0.22 10.4 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_17 PF13207.6 OAP57416.1 - 0.18 12.2 0.2 0.18 12.2 0.2 2.2 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 OAP57416.1 - 0.19 12.1 0.0 0.33 11.3 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.6 OAP57416.1 - 0.68 10.1 0.0 0.68 10.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain MHYT PF03707.16 OAP57417.1 - 7.1e-20 70.9 11.3 1.4e-09 38.0 0.3 3.6 3 0 0 3 3 3 3 Bacterial signalling protein N terminal repeat Peptidase_S10 PF00450.22 OAP57418.1 - 7.8e-114 381.3 0.0 1e-113 380.9 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase RRM_1 PF00076.22 OAP57420.1 - 1.3e-08 34.5 0.0 2.4e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sulfotransfer_4 PF17784.1 OAP57421.1 - 2.9e-48 164.6 0.1 4.8e-48 163.8 0.1 1.3 1 0 0 1 1 1 1 Sulfotransferase domain RNase_PH PF01138.21 OAP57421.1 - 3.1e-13 50.4 0.1 9.5e-13 48.8 0.0 1.8 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 Sulfotransfer_3 PF13469.6 OAP57421.1 - 7.9e-08 32.9 1.0 5.6e-05 23.6 0.0 2.4 1 1 0 2 2 2 2 Sulfotransferase family Sulfotransfer_1 PF00685.27 OAP57421.1 - 0.064 12.7 0.0 0.096 12.1 0.0 1.2 1 0 0 1 1 1 0 Sulfotransferase domain GCP_C_terminal PF04130.13 OAP57422.1 - 6.7e-24 84.9 0.3 9.9e-24 84.3 0.3 1.2 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 OAP57422.1 - 3.8e-23 82.6 0.0 8.2e-23 81.5 0.0 1.5 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal UDPG_MGDP_dh_C PF03720.15 OAP57422.1 - 0.036 14.5 0.0 0.12 12.8 0.0 1.8 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain ThiF PF00899.21 OAP57423.1 - 4e-117 389.8 0.0 4.2e-77 258.8 0.0 2.4 2 1 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 OAP57423.1 - 1.5e-90 303.6 1.7 1.5e-90 303.5 0.1 1.8 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site E1_UFD PF09358.10 OAP57423.1 - 7.4e-31 106.7 0.0 1.9e-30 105.4 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin fold domain E1_FCCH PF16190.5 OAP57423.1 - 6.9e-29 99.9 0.0 1.8e-28 98.5 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_4HB PF16191.5 OAP57423.1 - 1.2e-26 92.7 2.2 1.7e-26 92.2 0.6 2.2 2 0 0 2 2 2 1 Ubiquitin-activating enzyme E1 four-helix bundle NAD_binding_7 PF13241.6 OAP57423.1 - 0.089 13.2 0.1 0.67 10.4 0.0 2.5 3 0 0 3 3 3 0 Putative NAD(P)-binding GST_N_2 PF13409.6 OAP57424.1 - 1.4e-23 82.9 0.3 1.3e-22 79.8 0.1 2.5 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAP57424.1 - 5.2e-17 61.6 0.0 1.9e-16 59.8 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OAP57424.1 - 2.9e-06 27.4 0.0 8.7e-06 25.9 0.0 2.1 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 OAP57424.1 - 9.9e-06 25.9 0.1 0.0002 21.7 0.1 2.6 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_5 PF16865.5 OAP57424.1 - 0.0005 20.6 0.0 0.00091 19.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OAP57424.1 - 0.00052 20.2 0.0 0.0012 19.0 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Peptidase_M7 PF02031.16 OAP57425.1 - 0.015 15.5 0.1 0.033 14.3 0.1 1.6 1 0 0 1 1 1 0 Streptomyces extracellular neutral proteinase (M7) family MFS_1 PF07690.16 OAP57427.1 - 7.7e-40 136.9 50.7 7.7e-40 136.9 50.7 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 OAP57427.1 - 1.8e-14 53.1 25.1 2.8e-14 52.5 25.1 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF4029 PF13221.6 OAP57427.1 - 0.043 14.4 1.6 0.18 12.4 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4029) DUF2919 PF11143.8 OAP57427.1 - 0.13 12.6 3.5 0.15 12.4 0.6 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2919) Phage_holin_2_3 PF16080.5 OAP57427.1 - 0.52 10.1 5.1 24 4.8 0.0 3.7 3 0 0 3 3 3 0 Bacteriophage holin family HP1 Zn_clus PF00172.18 OAP57428.1 - 0.0033 17.5 11.1 0.0073 16.4 11.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3176 PF11374.8 OAP57429.1 - 3.3e-18 65.9 4.3 9.3e-18 64.4 4.3 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) YbhQ PF11076.8 OAP57429.1 - 2 8.4 3.9 0.5 10.4 0.6 1.7 2 0 0 2 2 2 0 Putative inner membrane protein YbhQ OB_NTP_bind PF07717.16 OAP57430.1 - 4.9e-18 65.3 0.0 1e-17 64.3 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 OAP57430.1 - 4.4e-15 55.9 0.0 1.3e-14 54.4 0.0 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 OAP57430.1 - 7.4e-14 52.0 0.0 1.6e-13 51.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RWD PF05773.22 OAP57430.1 - 8.1e-11 42.2 0.0 1.7e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 RWD domain DEAD PF00270.29 OAP57430.1 - 5.2e-08 32.9 0.1 1.2e-07 31.7 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_29 PF13555.6 OAP57430.1 - 0.0013 18.4 0.0 0.0032 17.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_19 PF13245.6 OAP57430.1 - 0.0022 18.3 0.0 0.0051 17.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 OAP57430.1 - 0.0027 17.1 0.0 0.0062 15.9 0.0 1.5 1 0 0 1 1 1 1 KaiC AAA_23 PF13476.6 OAP57430.1 - 0.0072 16.9 0.0 0.022 15.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 OAP57430.1 - 0.0087 15.7 0.0 0.02 14.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain UBA PF00627.31 OAP57430.1 - 0.015 15.2 0.0 7.7 6.5 0.0 3.0 2 0 0 2 2 2 0 UBA/TS-N domain SMC_N PF02463.19 OAP57430.1 - 0.015 14.7 0.1 0.029 13.8 0.1 1.4 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Sigma54_activat PF00158.26 OAP57430.1 - 0.018 14.8 0.0 0.23 11.2 0.0 2.6 3 0 0 3 3 3 0 Sigma-54 interaction domain ResIII PF04851.15 OAP57430.1 - 0.018 15.1 0.0 0.039 13.9 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_22 PF13401.6 OAP57430.1 - 0.018 15.3 0.3 0.06 13.6 0.3 1.8 1 1 0 1 1 1 0 AAA domain Zot PF05707.12 OAP57430.1 - 0.019 14.6 0.0 0.037 13.7 0.0 1.5 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) AAA_30 PF13604.6 OAP57430.1 - 0.02 14.6 0.1 0.11 12.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 OAP57430.1 - 0.037 13.4 0.0 0.082 12.3 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family T2SSE PF00437.20 OAP57430.1 - 0.098 11.7 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein HOIP-UBA PF16678.5 OAP57430.1 - 0.11 12.4 0.1 23 5.0 0.0 2.9 2 0 0 2 2 2 0 HOIP UBA domain pair PhoH PF02562.16 OAP57430.1 - 0.16 11.4 0.0 0.29 10.6 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein Cyclin_N PF00134.23 OAP57431.1 - 7.9e-45 151.7 0.5 1.5e-44 150.8 0.5 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 OAP57431.1 - 4.2e-35 120.4 0.1 1.6e-34 118.6 0.1 2.1 1 0 0 1 1 1 1 Cyclin, C-terminal domain Zn_clus PF00172.18 OAP57432.1 - 0.0017 18.4 12.2 0.0032 17.6 12.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RNA_pol_Rpc4 PF05132.14 OAP57433.1 - 2e-30 106.2 0.0 2e-30 106.2 0.0 3.4 3 0 0 3 3 3 1 RNA polymerase III RPC4 Pep1_7 PF17232.2 OAP57433.1 - 0.16 12.5 4.2 0.8 10.2 1.1 2.7 2 0 0 2 2 2 0 Elicitor peptide 1-7 KRE1 PF17056.5 OAP57434.1 - 2.4e-11 43.2 0.2 4.9e-11 42.2 0.2 1.4 1 0 0 1 1 1 1 Killer toxin-resistance protein 1 DUF1177 PF06675.11 OAP57434.1 - 0.17 10.7 1.1 0.28 10.0 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1177) SepZ PF06066.11 OAP57434.1 - 0.52 10.5 3.3 0.27 11.5 0.3 2.0 2 1 1 3 3 3 0 SepZ CRCB PF02537.15 OAP57435.1 - 2.7e-36 123.8 12.5 1.3e-22 79.8 7.5 2.4 2 0 0 2 2 2 2 CrcB-like protein, Camphor Resistance (CrcB) UPRTase PF14681.6 OAP57436.1 - 1.5e-72 243.4 0.0 1.7e-72 243.2 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 OAP57436.1 - 3.5e-07 29.9 0.1 8.6e-07 28.6 0.1 1.5 1 1 0 1 1 1 1 Phosphoribosyl transferase domain UreD PF01774.17 OAP57437.1 - 3.3e-70 236.3 0.0 4.1e-70 236.0 0.0 1.1 1 0 0 1 1 1 1 UreD urease accessory protein STAG PF08514.11 OAP57438.1 - 1.8e-34 118.1 0.6 1.8e-34 118.1 0.6 2.9 3 0 0 3 3 3 1 STAG domain HEAT_2 PF13646.6 OAP57438.1 - 8e-05 23.0 1.2 0.034 14.5 0.2 3.9 2 1 1 3 3 3 1 HEAT repeats YL1 PF05764.13 OAP57438.1 - 0.0056 16.8 23.9 0.0056 16.8 23.9 4.4 3 1 0 3 3 3 1 YL1 nuclear protein DUF4446 PF14584.6 OAP57438.1 - 0.64 10.0 3.1 0.55 10.2 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) DUF4679 PF15728.5 OAP57438.1 - 9.5 5.1 8.5 16 4.4 8.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4679) TRAP_alpha PF03896.16 OAP57439.1 - 1.2e-10 41.1 0.0 1.6e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit Herpes_capsid PF06112.11 OAP57440.1 - 0.61 10.1 5.2 1.1 9.3 5.2 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein DUF3093 PF11292.8 OAP57441.1 - 6.1 7.1 7.9 0.27 11.5 1.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3093) PhyH PF05721.13 OAP57443.1 - 2.8e-11 44.1 0.0 4.3e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) R3H PF01424.22 OAP57444.1 - 0.42 10.6 2.5 0.7 9.9 0.7 2.3 2 0 0 2 2 2 0 R3H domain MFS_1 PF07690.16 OAP57445.1 - 2.2e-27 95.9 22.6 3.2e-27 95.4 22.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAP57445.1 - 4.5e-12 45.6 9.4 4.5e-12 45.6 9.4 2.9 3 1 1 4 4 4 1 Sugar (and other) transporter HMG-CoA_red PF00368.18 OAP57445.1 - 0.12 11.4 0.3 0.18 10.8 0.3 1.1 1 0 0 1 1 1 0 Hydroxymethylglutaryl-coenzyme A reductase Fungal_trans_2 PF11951.8 OAP57446.1 - 5.3e-19 68.3 5.0 7.6e-19 67.8 5.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP57446.1 - 5.6e-05 23.2 12.6 0.0001 22.3 12.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amidase PF01425.21 OAP57447.1 - 3.3e-92 309.8 0.0 4.3e-92 309.4 0.0 1.1 1 0 0 1 1 1 1 Amidase AMP-binding PF00501.28 OAP57448.1 - 3.1e-85 286.3 0.0 3.9e-85 286.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAP57448.1 - 1.5e-13 51.5 1.6 4.4e-13 50.0 1.6 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Wyosine_form PF08608.12 OAP57449.1 - 1.5e-24 86.1 0.0 3.4e-24 85.0 0.0 1.7 1 0 0 1 1 1 1 Wyosine base formation Radical_SAM PF04055.21 OAP57449.1 - 2e-19 70.6 0.1 5e-19 69.3 0.1 1.7 1 1 0 1 1 1 1 Radical SAM superfamily Flavodoxin_1 PF00258.25 OAP57449.1 - 1.9e-07 31.4 0.0 2.5e-06 27.7 0.0 2.5 1 1 0 1 1 1 1 Flavodoxin DUF4524 PF15025.6 OAP57449.1 - 0.063 13.0 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4524) EF-hand_1 PF00036.32 OAP57450.1 - 0.076 12.6 0.1 0.13 11.8 0.1 1.4 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.6 OAP57450.1 - 0.081 12.9 0.1 0.17 11.9 0.1 1.5 1 0 0 1 1 1 0 EF-hand domain MFS_1 PF07690.16 OAP57451.1 - 2e-31 109.2 32.5 2e-31 109.2 32.5 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAP57451.1 - 3.8e-07 29.4 18.5 8.4e-06 24.9 18.5 2.7 1 1 0 1 1 1 1 Sugar (and other) transporter Malic_M PF03949.15 OAP57451.1 - 0.12 11.6 0.0 0.24 10.6 0.0 1.4 1 0 0 1 1 1 0 Malic enzyme, NAD binding domain PhaG_MnhG_YufB PF03334.14 OAP57451.1 - 2.2 8.6 8.9 0.89 9.8 4.0 2.9 2 0 0 2 2 2 0 Na+/H+ antiporter subunit Isochorismatase PF00857.20 OAP57452.1 - 6.6e-29 101.3 0.0 7.8e-29 101.1 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family PNP_UDP_1 PF01048.20 OAP57452.1 - 0.056 12.7 0.0 0.087 12.1 0.0 1.3 1 0 0 1 1 1 0 Phosphorylase superfamily PHD PF00628.29 OAP57453.1 - 2.9e-07 30.3 7.1 4.8e-07 29.6 7.1 1.4 1 0 0 1 1 1 1 PHD-finger Mod_r PF07200.13 OAP57453.1 - 0.0006 19.9 3.5 0.0006 19.9 3.5 1.8 2 0 0 2 2 2 1 Modifier of rudimentary (Mod(r)) protein SHE3 PF17078.5 OAP57453.1 - 0.0018 18.0 2.1 0.0038 17.0 2.1 1.5 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 C1_1 PF00130.22 OAP57453.1 - 0.0041 17.0 1.3 0.0081 16.0 1.3 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_4 PF16866.5 OAP57453.1 - 0.008 16.2 4.3 0.02 15.0 4.3 1.7 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 OAP57453.1 - 0.011 15.9 3.9 0.025 14.8 3.9 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-PHD-like PF15446.6 OAP57453.1 - 0.017 14.8 1.2 0.047 13.3 1.2 1.8 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain SlyX PF04102.12 OAP57453.1 - 0.021 15.4 3.1 0.021 15.4 3.1 2.6 2 0 0 2 2 2 0 SlyX Zf_RING PF16744.5 OAP57453.1 - 0.024 14.8 1.1 0.048 13.8 1.1 1.4 1 0 0 1 1 1 0 KIAA1045 RING finger DUF2353 PF09789.9 OAP57453.1 - 0.025 13.9 7.2 0.04 13.3 7.2 1.2 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) Csm1_N PF18504.1 OAP57453.1 - 0.068 13.5 8.6 1.5 9.2 0.9 3.4 2 1 1 3 3 3 0 Csm1 N-terminal domain Rootletin PF15035.6 OAP57453.1 - 0.082 12.9 10.6 0.15 12.1 10.4 1.6 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DUF5082 PF16888.5 OAP57453.1 - 0.1 12.9 8.1 3.3 8.0 1.8 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF5082) PI3K_P85_iSH2 PF16454.5 OAP57453.1 - 0.11 12.1 6.8 0.18 11.4 6.8 1.2 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Lzipper-MIP1 PF14389.6 OAP57453.1 - 0.14 12.5 5.0 0.41 11.0 4.0 2.3 1 1 1 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 YabA PF06156.13 OAP57453.1 - 0.17 12.5 7.9 0.11 13.2 4.3 2.2 1 1 0 2 2 2 0 Initiation control protein YabA DivIC PF04977.15 OAP57453.1 - 0.18 11.6 9.9 0.4 10.5 2.3 2.6 1 1 1 2 2 2 0 Septum formation initiator Prok-RING_1 PF14446.6 OAP57453.1 - 0.24 11.3 6.7 0.1 12.5 4.2 1.7 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 ZapB PF06005.12 OAP57453.1 - 0.28 11.6 13.0 0.1 13.0 7.4 2.3 2 0 0 2 2 2 0 Cell division protein ZapB TSC22 PF01166.18 OAP57453.1 - 0.32 11.3 6.8 0.59 10.5 1.6 2.6 2 1 0 2 2 2 0 TSC-22/dip/bun family DUF4140 PF13600.6 OAP57453.1 - 0.36 11.3 6.3 5 7.6 1.4 2.8 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) UPF0242 PF06785.11 OAP57453.1 - 0.85 9.7 5.7 1.3 9.1 5.7 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Atg14 PF10186.9 OAP57453.1 - 1 8.3 12.4 1.4 7.9 6.2 2.6 2 1 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Cnn_1N PF07989.11 OAP57453.1 - 1.1 9.5 7.3 0.43 10.8 3.1 2.2 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 ATG16 PF08614.11 OAP57453.1 - 6.3 7.0 20.2 5 7.3 18.8 1.6 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF4472 PF14739.6 OAP57453.1 - 7.2 7.4 11.9 9.5 7.0 6.9 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4472) Aminotran_5 PF00266.19 OAP57454.1 - 3e-18 65.9 0.0 5.3e-18 65.1 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 OAP57454.1 - 0.0084 14.7 0.0 0.04 12.4 0.0 1.9 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 OAP57454.1 - 0.031 13.6 0.2 7.1 5.8 0.0 2.1 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family YajC PF02699.15 OAP57454.1 - 0.06 13.2 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Preprotein translocase subunit tRNA_int_end_N2 PF12928.7 OAP57455.1 - 5.3e-21 74.6 0.3 1.1e-20 73.5 0.1 1.7 2 0 0 2 2 2 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.14 OAP57455.1 - 0.0058 16.3 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, N-terminal domain Skp1_POZ PF03931.15 OAP57456.1 - 3.2e-12 46.4 0.0 4.2e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain BTB PF00651.31 OAP57456.1 - 0.0052 17.0 0.0 0.0067 16.6 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain ThiF PF00899.21 OAP57457.1 - 6.9e-72 241.7 0.0 9.4e-72 241.3 0.0 1.1 1 0 0 1 1 1 1 ThiF family UAE_UbL PF14732.6 OAP57457.1 - 1.2e-18 67.4 1.8 2.5e-18 66.4 0.6 2.1 2 0 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.9 OAP57457.1 - 1.3e-12 48.2 0.9 2.1e-07 31.2 0.0 2.6 1 1 1 2 2 2 2 Ubiquitin-activating enzyme active site NAD_binding_7 PF13241.6 OAP57457.1 - 0.0024 18.3 0.0 0.011 16.2 0.0 2.1 2 0 0 2 2 2 1 Putative NAD(P)-binding Pyr_redox PF00070.27 OAP57457.1 - 0.0062 17.1 1.3 3.1 8.4 0.1 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 OAP57457.1 - 0.017 15.2 0.0 0.04 14.0 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Kinesin_assoc PF16183.5 OAP57457.1 - 0.16 12.1 0.6 0.3 11.2 0.6 1.3 1 0 0 1 1 1 0 Kinesin-associated Q_salvage PF10343.9 OAP57458.1 - 1.9e-126 421.4 0.0 2.3e-126 421.1 0.0 1.0 1 0 0 1 1 1 1 Potential Queuosine, Q, salvage protein family PEMT PF04191.13 OAP57459.1 - 7.1e-62 206.4 8.3 5.9e-38 129.5 0.5 2.6 2 0 0 2 2 2 2 Phospholipid methyltransferase HECW_N PF16562.5 OAP57459.1 - 0.0072 16.1 0.0 0.024 14.4 0.0 1.8 1 1 0 1 1 1 1 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 ParA PF10609.9 OAP57460.1 - 3.1e-97 324.9 0.0 3.6e-97 324.7 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 OAP57460.1 - 7.4e-08 32.5 0.0 2e-07 31.1 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 OAP57460.1 - 1e-05 25.5 0.0 3.8e-05 23.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.15 OAP57460.1 - 1.5e-05 24.4 0.9 0.00049 19.4 0.2 2.6 1 1 1 3 3 3 1 Anion-transporting ATPase AAA_26 PF13500.6 OAP57460.1 - 0.0065 16.3 0.0 0.27 11.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 OAP57460.1 - 0.029 14.3 0.0 0.061 13.2 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_30 PF13604.6 OAP57460.1 - 0.056 13.1 0.0 0.079 12.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain MipZ PF09140.11 OAP57460.1 - 0.06 12.6 0.0 0.12 11.6 0.0 1.5 1 1 0 1 1 1 0 ATPase MipZ CLP1_P PF16575.5 OAP57460.1 - 0.067 13.0 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_18 PF13238.6 OAP57460.1 - 0.076 13.6 0.0 0.12 12.9 0.0 1.4 1 1 0 1 1 1 0 AAA domain Fer4_NifH PF00142.18 OAP57460.1 - 0.08 12.4 0.0 1.5 8.2 0.0 2.2 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family Asp PF00026.23 OAP57461.1 - 2.6e-61 207.8 4.0 3.1e-61 207.5 4.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OAP57461.1 - 1.7e-05 25.1 1.7 0.096 12.9 0.2 2.6 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 OAP57461.1 - 0.00011 22.8 4.2 0.13 12.9 1.2 3.4 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 OAP57461.1 - 0.048 14.2 2.1 10 6.8 0.4 3.5 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease CRT10 PF08728.10 OAP57461.1 - 0.18 9.9 0.0 0.25 9.5 0.0 1.1 1 0 0 1 1 1 0 CRT10 Thr_synth_N PF14821.6 OAP57463.1 - 1.4e-23 82.9 0.0 3.8e-23 81.5 0.0 1.8 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.25 OAP57463.1 - 5.6e-18 65.4 0.0 3.7e-17 62.7 0.0 2.0 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF302 PF03625.14 OAP57464.1 - 3.8e-05 23.5 0.0 6.1e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF302 Ammonium_transp PF00909.21 OAP57466.1 - 7.5e-74 248.8 18.9 8.6e-74 248.6 18.9 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family AA_permease_2 PF13520.6 OAP57467.1 - 5.2e-46 157.3 48.7 7e-46 156.9 48.7 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAP57467.1 - 3.4e-26 91.9 43.2 4.5e-26 91.5 43.2 1.0 1 0 0 1 1 1 1 Amino acid permease Phenol_monoox PF04663.12 OAP57467.1 - 1.3 9.3 5.9 3.3 7.9 0.0 3.4 3 0 0 3 3 3 0 Phenol hydroxylase conserved region Abhydrolase_3 PF07859.13 OAP57468.1 - 3.6e-60 203.4 0.9 5.1e-60 202.9 0.9 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 OAP57468.1 - 0.0041 16.0 0.6 0.022 13.6 0.0 1.9 2 0 0 2 2 2 1 Carboxylesterase family Chlorophyllase2 PF12740.7 OAP57468.1 - 0.028 13.3 0.0 0.042 12.8 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme adh_short_C2 PF13561.6 OAP57469.1 - 4.5e-49 167.1 0.1 1e-46 159.4 0.1 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP57469.1 - 4.7e-33 114.3 0.0 4.2e-31 107.9 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAP57469.1 - 2.3e-08 34.2 0.0 3.5e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAP57469.1 - 0.089 12.2 0.5 0.56 9.6 0.7 2.2 3 1 0 3 3 3 0 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.26 OAP57470.1 - 2.2e-25 89.1 2.3 3.5e-25 88.5 2.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAP57470.1 - 5.2e-11 43.7 0.0 9.1e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAP57470.1 - 7.8e-05 22.5 0.9 0.00048 20.0 0.0 2.6 2 2 2 4 4 4 1 Alcohol dehydrogenase GroES-like domain ACP_syn_III_C PF08541.10 OAP57470.1 - 0.022 14.9 1.2 0.067 13.4 0.2 2.3 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ATP-synt_J PF04911.12 OAP57471.1 - 1.6e-25 88.4 1.2 1.8e-25 88.3 1.2 1.0 1 0 0 1 1 1 1 ATP synthase j chain DASH_Spc19 PF08287.11 OAP57472.1 - 2.7e-51 173.6 3.0 3.5e-51 173.2 3.0 1.2 1 0 0 1 1 1 1 Spc19 Prefoldin_2 PF01920.20 OAP57472.1 - 0.007 16.3 5.5 2 8.4 3.4 2.6 3 0 0 3 3 3 2 Prefoldin subunit TPR_MLP1_2 PF07926.12 OAP57472.1 - 0.021 14.9 6.3 0.15 12.2 0.0 2.5 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein ADIP PF11559.8 OAP57472.1 - 0.077 13.1 7.7 0.67 10.0 2.1 3.0 2 1 0 3 3 3 0 Afadin- and alpha -actinin-Binding Syntaxin_2 PF14523.6 OAP57472.1 - 0.16 12.4 5.2 2.7 8.4 5.2 2.5 1 1 0 1 1 1 0 Syntaxin-like protein ECM11 PF15463.6 OAP57472.1 - 0.25 11.9 5.2 2 9.0 0.1 2.2 2 0 0 2 2 2 0 Extracellular mutant protein 11 DUF3086 PF11285.8 OAP57472.1 - 4.7 6.2 8.4 0.7 8.9 4.2 1.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3086) zf-CCCH PF00642.24 OAP57473.1 - 2.1e-05 24.3 1.6 2.1e-05 24.3 1.6 2.8 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 OAP57473.1 - 0.011 15.8 5.1 0.011 15.8 5.1 2.5 3 0 0 3 3 3 0 Zinc finger domain Suppressor_APC PF11414.8 OAP57473.1 - 0.031 14.3 0.5 0.056 13.5 0.5 1.4 1 0 0 1 1 1 0 Adenomatous polyposis coli tumour suppressor protein RasGAP_C PF03836.15 OAP57473.1 - 0.044 13.9 0.1 0.085 13.0 0.1 1.4 1 0 0 1 1 1 0 RasGAP C-terminus DUF4942 PF13708.6 OAP57473.1 - 0.066 13.2 1.0 0.093 12.7 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4942) Torus PF16131.5 OAP57473.1 - 0.074 13.8 1.5 0.23 12.2 0.1 2.4 2 0 0 2 2 2 0 Torus domain JIP_LZII PF16471.5 OAP57473.1 - 0.19 11.9 1.7 0.32 11.2 1.7 1.4 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II DUF4404 PF14357.6 OAP57473.1 - 0.36 11.5 1.7 0.85 10.3 1.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) MSA-2c PF12238.8 OAP57473.1 - 0.88 9.5 8.9 6.7 6.7 0.1 2.4 2 0 0 2 2 2 0 Merozoite surface antigen 2c Nab2p_Zf1 PF18260.1 OAP57473.1 - 1.5 8.8 10.2 1.9 8.4 4.3 2.4 2 0 0 2 2 2 0 Nuclear polyadenylated RNA-binding 2 protein CCCH zinc finger 1 zf-CCCH_4 PF18044.1 OAP57473.1 - 9.4 6.2 12.5 0.085 12.7 3.6 2.2 2 0 0 2 2 2 0 CCCH-type zinc finger Peptidase_M20 PF01546.28 OAP57474.1 - 2.9e-27 95.7 0.1 4.8e-27 95.0 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 OAP57474.1 - 1.4e-14 54.0 0.0 2.2e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain PAX PF00292.18 OAP57474.1 - 0.057 13.4 0.0 4.2 7.3 0.0 2.3 2 0 0 2 2 2 0 'Paired box' domain NMT1_2 PF13379.6 OAP57474.1 - 0.13 12.0 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 NMT1-like family FAD_binding_7 PF03441.14 OAP57475.1 - 2e-72 243.0 0.1 2e-72 243.0 0.1 1.5 2 0 0 2 2 2 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 OAP57475.1 - 5.5e-35 120.8 0.3 1.1e-34 119.8 0.3 1.5 1 0 0 1 1 1 1 DNA photolyase NAD_binding_8 PF13450.6 OAP57475.1 - 0.034 14.4 0.0 0.088 13.1 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Glyco_hydro_3_C PF01915.22 OAP57476.1 - 1.7e-51 175.1 0.0 4.8e-51 173.6 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 OAP57476.1 - 4.2e-40 138.1 0.0 7.6e-40 137.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 OAP57476.1 - 1.1e-16 60.7 0.1 2.1e-16 59.8 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain PIR PF00399.19 OAP57476.1 - 1.1e-11 43.9 31.2 5.2e-06 25.9 6.3 3.7 2 1 1 3 3 3 3 Yeast PIR protein repeat ECF_trnsprt PF12822.7 OAP57477.1 - 0.012 15.7 2.1 0.019 15.1 2.1 1.4 1 0 0 1 1 1 0 ECF transporter, substrate-specific component EBP PF05241.12 OAP57477.1 - 0.41 10.1 8.9 0.11 12.0 5.8 1.7 1 1 0 1 1 1 0 Emopamil binding protein ECH_1 PF00378.20 OAP57478.1 - 2.7e-25 89.1 0.0 3.5e-25 88.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAP57478.1 - 6.7e-10 39.0 0.0 8e-10 38.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Med31 PF05669.12 OAP57479.1 - 6e-30 103.1 1.1 8.2e-30 102.7 1.1 1.1 1 0 0 1 1 1 1 SOH1 Pal1 PF08316.11 OAP57480.1 - 6.9e-49 166.1 0.3 1.6e-48 165.0 0.0 1.8 2 0 0 2 2 2 1 Pal1 cell morphology protein ThrE PF06738.12 OAP57481.1 - 0.012 15.0 0.4 3 7.1 0.0 2.3 2 0 0 2 2 2 0 Putative threonine/serine exporter zf-Mss51 PF13824.6 OAP57482.1 - 1.7 8.8 8.9 9.1 6.5 0.0 3.7 3 1 0 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 AAA_16 PF13191.6 OAP57483.1 - 1.7e-05 25.3 0.0 4.2e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.13 OAP57483.1 - 0.02 14.1 0.0 0.037 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ATP-synt_ab PF00006.25 OAP57483.1 - 0.064 12.9 0.0 0.56 9.8 0.0 2.1 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_7 PF12775.7 OAP57483.1 - 0.08 12.4 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_29 PF13555.6 OAP57483.1 - 0.17 11.7 0.1 0.33 10.7 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 OAP57483.1 - 0.18 12.0 0.3 0.55 10.5 0.3 1.8 1 1 0 1 1 1 0 AAA domain CLU PF13236.6 OAP57484.1 - 4.1e-75 252.4 0.0 7.6e-75 251.5 0.0 1.5 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 OAP57484.1 - 1.3e-51 175.2 0.6 6.6e-51 172.8 0.0 2.4 3 0 0 3 3 3 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.6 OAP57484.1 - 3.5e-26 91.3 2.6 1.4e-13 50.9 0.0 4.2 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_10 PF13374.6 OAP57484.1 - 2.6e-25 87.5 0.2 7e-07 28.9 0.0 5.7 5 0 0 5 5 5 3 Tetratricopeptide repeat CLU_N PF15044.6 OAP57484.1 - 2.8e-25 88.5 0.6 9.9e-25 86.7 0.6 2.0 1 0 0 1 1 1 1 Mitochondrial function, CLU-N-term DUF727 PF05303.12 OAP57484.1 - 1.5e-05 25.0 0.0 4.1e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF727) TPR_2 PF07719.17 OAP57484.1 - 1.7e-05 24.5 1.9 10 6.5 0.0 5.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 OAP57484.1 - 7.8e-05 22.6 2.5 0.54 10.6 0.2 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_MalT PF17874.1 OAP57484.1 - 0.074 12.4 3.8 0.33 10.3 3.9 1.9 1 1 0 1 1 1 0 MalT-like TPR region UPF0016 PF01169.19 OAP57484.1 - 0.18 12.2 0.0 0.4 11.0 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein family UPF0016 BRF1 PF07741.13 OAP57484.1 - 0.93 9.9 4.0 3 8.2 0.4 2.9 2 0 0 2 2 2 0 Brf1-like TBP-binding domain WD40 PF00400.32 OAP57487.1 - 2.4e-29 101.0 7.8 2e-05 25.3 0.2 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.7 OAP57487.1 - 7e-09 35.5 0.5 1.5e-08 34.4 0.5 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAP57487.1 - 2.8e-07 30.2 0.3 5.4e-07 29.3 0.3 1.5 1 0 0 1 1 1 1 F-box domain ANAPC4_WD40 PF12894.7 OAP57487.1 - 4.1e-06 27.0 0.1 0.41 11.0 0.0 4.4 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain F-box_4 PF15966.5 OAP57487.1 - 0.00032 20.5 0.1 0.00062 19.6 0.1 1.4 1 0 0 1 1 1 1 F-box Nup160 PF11715.8 OAP57487.1 - 0.0004 19.2 0.0 0.091 11.4 0.0 3.3 4 0 0 4 4 4 1 Nucleoporin Nup120/160 DUF4592 PF15262.6 OAP57487.1 - 0.0079 16.9 0.7 0.017 15.8 0.7 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4592) BBS2_Mid PF14783.6 OAP57487.1 - 0.018 15.1 0.1 16 5.6 0.0 3.7 3 1 0 4 4 4 0 Ciliary BBSome complex subunit 2, middle region WD40_like PF17005.5 OAP57487.1 - 0.13 11.5 0.0 22 4.2 0.0 3.0 3 0 0 3 3 3 0 WD40-like domain Forkhead PF00250.18 OAP57488.1 - 3.5e-34 116.9 0.7 6.2e-34 116.1 0.7 1.4 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 OAP57488.1 - 1.8e-08 34.6 0.0 4e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 FHA domain Linker_histone PF00538.19 OAP57488.1 - 0.18 12.2 0.6 3.2 8.2 0.1 2.4 2 0 0 2 2 2 0 linker histone H1 and H5 family DUF3245 PF11595.8 OAP57488.1 - 0.92 10.0 4.4 0.52 10.8 0.2 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3245) RRM_1 PF00076.22 OAP57490.1 - 4.7e-13 48.7 0.0 9.1e-06 25.4 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G-patch PF01585.23 OAP57490.1 - 6.9e-10 38.7 1.1 1.4e-09 37.7 1.1 1.6 1 0 0 1 1 1 1 G-patch domain zf-RanBP PF00641.18 OAP57490.1 - 4.1e-09 35.6 1.4 7.4e-09 34.8 1.4 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others G-patch_2 PF12656.7 OAP57490.1 - 1.5e-06 28.2 0.1 4.7e-06 26.6 0.1 1.8 1 0 0 1 1 1 1 G-patch domain NCD3G PF07562.14 OAP57490.1 - 5.6 7.0 6.3 13 5.8 1.6 2.4 2 0 0 2 2 2 0 Nine Cysteines Domain of family 3 GPCR Yae1_N PF09811.9 OAP57491.1 - 6.9e-10 38.5 0.6 1.1e-09 37.9 0.6 1.3 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Sigma70_ner PF04546.13 OAP57491.1 - 2.8 7.8 6.6 0.8 9.5 1.5 2.0 2 0 0 2 2 2 0 Sigma-70, non-essential region Acatn PF13000.7 OAP57492.1 - 7.6e-154 513.2 17.6 8.4e-81 272.1 8.4 3.1 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 LAP1C PF05609.12 OAP57492.1 - 3 6.8 8.3 4.5 6.3 8.3 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF996 PF06195.13 OAP57492.1 - 5.2 7.4 13.7 0.55 10.5 1.3 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF996) DUF4637 PF15470.6 OAP57492.1 - 9.8 5.9 9.0 24 4.6 9.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) CENP-O PF09496.10 OAP57493.1 - 7.1e-49 166.7 0.0 1.7e-48 165.4 0.0 1.6 1 1 0 1 1 1 1 Cenp-O kinetochore centromere component Cyclase PF04199.13 OAP57494.1 - 6.8e-12 45.8 0.0 1.4e-11 44.8 0.0 1.4 1 1 0 1 1 1 1 Putative cyclase Ge1_WD40 PF16529.5 OAP57494.1 - 0.15 11.0 0.6 0.21 10.5 0.6 1.1 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein adh_short_C2 PF13561.6 OAP57495.1 - 5.2e-65 219.3 1.5 5.8e-65 219.1 1.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP57495.1 - 8.8e-50 168.9 0.7 1.2e-49 168.5 0.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAP57495.1 - 7.8e-08 32.4 1.2 1.4e-07 31.6 1.2 1.4 1 1 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 OAP57495.1 - 0.015 15.6 0.1 0.1 12.8 0.1 2.2 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain ADH_zinc_N PF00107.26 OAP57495.1 - 0.05 13.6 0.2 0.084 12.9 0.2 1.5 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Ldh_1_N PF00056.23 OAP57495.1 - 0.056 13.5 0.2 0.099 12.7 0.2 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Epimerase PF01370.21 OAP57495.1 - 0.084 12.3 0.1 2.4 7.5 0.2 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Cytochrom_C PF00034.21 OAP57495.1 - 0.097 13.8 0.0 0.22 12.7 0.0 1.7 1 0 0 1 1 1 0 Cytochrome c Sugar_tr PF00083.24 OAP57496.1 - 2.8e-88 296.8 16.2 3.2e-88 296.6 16.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP57496.1 - 3.8e-26 91.9 28.5 2.3e-21 76.1 18.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 OAP57496.1 - 7.6e-05 21.4 3.0 7.6e-05 21.4 3.0 2.8 2 1 1 3 3 3 1 MFS/sugar transport protein WTF PF03303.13 OAP57496.1 - 0.13 12.0 0.2 0.25 11.1 0.2 1.4 1 0 0 1 1 1 0 WTF protein TRI12 PF06609.13 OAP57497.1 - 6.7e-41 140.4 23.0 8.6e-41 140.0 23.0 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAP57497.1 - 3.2e-15 55.9 47.8 7.7e-15 54.7 45.1 2.2 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF3087 PF11286.8 OAP57497.1 - 0.098 12.1 4.7 1.3 8.5 0.8 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3087) SpoIIIAC PF06686.11 OAP57497.1 - 7.9 6.7 9.3 0.62 10.3 0.2 3.7 3 1 0 3 3 3 0 Stage III sporulation protein AC/AD protein family adh_short_C2 PF13561.6 OAP57498.1 - 1.3e-59 201.7 0.1 1.6e-59 201.3 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP57498.1 - 1.3e-49 168.3 0.2 1.6e-49 168.1 0.2 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAP57498.1 - 1e-15 58.1 0.0 1.9e-15 57.2 0.0 1.4 1 1 0 1 1 1 1 KR domain Fungal_trans PF04082.18 OAP57499.1 - 4.1e-24 85.0 1.2 7e-24 84.3 1.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP57499.1 - 1e-05 25.5 12.8 1e-05 25.5 12.8 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain VWA_3 PF13768.6 OAP57499.1 - 0.1 12.5 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 von Willebrand factor type A domain Ureidogly_lyase PF04115.12 OAP57501.1 - 8.6e-11 41.9 0.0 5.2e-10 39.4 0.0 1.9 1 1 0 1 1 1 1 Ureidoglycolate lyase MAPEG PF01124.18 OAP57503.1 - 2e-12 47.1 3.9 2.6e-12 46.8 3.9 1.2 1 0 0 1 1 1 1 MAPEG family DUF1154 PF06631.11 OAP57504.1 - 0.1 12.6 3.2 0.56 10.3 3.2 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1154) DFP PF04127.15 OAP57505.1 - 5.5e-18 65.5 0.0 4.2e-10 39.8 0.0 2.2 2 0 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein RTA1 PF04479.13 OAP57506.1 - 5.5e-34 117.6 6.2 7.3e-34 117.2 6.2 1.2 1 0 0 1 1 1 1 RTA1 like protein NB PF04159.13 OAP57506.1 - 0.13 12.3 0.7 0.22 11.6 0.7 1.3 1 0 0 1 1 1 0 NB glycoprotein AAA_22 PF13401.6 OAP57508.1 - 0.00088 19.6 0.0 0.7 10.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.7 OAP57508.1 - 0.012 14.6 0.0 1.7 7.5 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain AAA_16 PF13191.6 OAP57508.1 - 0.14 12.5 0.0 3.2 8.1 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain Cu-oxidase_3 PF07732.15 OAP57509.1 - 1.1e-38 131.8 1.1 1.4e-35 121.9 0.0 3.3 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 OAP57509.1 - 1.1e-33 115.9 2.4 2.8e-25 88.6 0.1 3.3 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 OAP57509.1 - 4.3e-18 65.9 0.0 5.8e-17 62.3 0.0 2.6 2 1 0 2 2 2 1 Multicopper oxidase GFO_IDH_MocA PF01408.22 OAP57510.1 - 9.1e-09 36.2 0.4 2.1e-08 35.0 0.4 1.7 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold YAcAr PF10686.9 OAP57511.1 - 0.062 13.3 0.5 0.34 10.9 0.0 2.3 2 0 0 2 2 2 0 YspA, cpYpsA-related SLOG family Cation_ATPase_C PF00689.21 OAP57512.1 - 2.2e-47 161.1 9.2 2.2e-47 161.1 9.2 2.1 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 OAP57512.1 - 1.7e-37 128.7 0.2 1.7e-37 128.7 0.2 2.9 4 0 0 4 4 4 1 E1-E2 ATPase Cation_ATPase PF13246.6 OAP57512.1 - 1.1e-18 67.0 0.0 2.2e-18 66.1 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 OAP57512.1 - 1.7e-17 64.4 0.0 4.5e-17 63.0 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 OAP57512.1 - 9.8e-11 41.2 0.0 3.8e-10 39.3 0.0 2.1 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 OAP57512.1 - 0.00061 19.6 0.5 0.0053 16.5 0.0 2.5 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Ferlin_C PF16165.5 OAP57512.1 - 0.094 12.7 0.0 0.29 11.0 0.0 1.8 1 0 0 1 1 1 0 Ferlin C-terminus MFS_1 PF07690.16 OAP57513.1 - 4.8e-47 160.6 20.7 4.8e-47 160.6 20.7 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAP57513.1 - 3e-11 42.9 6.1 3e-11 42.9 6.1 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 OAP57513.1 - 0.0014 17.1 1.5 0.0014 17.1 1.5 1.4 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 OAP57513.1 - 0.99 7.6 6.1 3.9 5.7 1.2 2.6 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family MoaE PF02391.17 OAP57514.1 - 8.7e-35 119.4 0.0 1.1e-34 119.1 0.0 1.1 1 0 0 1 1 1 1 MoaE protein DUF4632 PF15451.6 OAP57514.1 - 0.096 12.8 0.3 0.21 11.7 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4632) SCO1-SenC PF02630.14 OAP57515.1 - 7.6e-45 152.1 0.0 1.1e-44 151.6 0.0 1.2 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 OAP57515.1 - 2.2e-05 24.4 0.0 3.5e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 OAP57515.1 - 0.0076 16.6 0.0 0.013 15.8 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Amidohydro_1 PF01979.20 OAP57516.1 - 4.9e-18 65.5 2.2 7.9e-18 64.9 2.2 1.3 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 OAP57516.1 - 1.2e-09 38.2 8.9 2.3e-05 24.1 3.7 3.8 1 1 0 2 2 2 2 Amidohydrolase family Cyt-b5 PF00173.28 OAP57517.1 - 4e-15 55.7 0.0 5.7e-15 55.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Gpr1_Fun34_YaaH PF01184.19 OAP57518.1 - 4.3e-71 238.8 15.9 5.4e-71 238.5 15.9 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family PNTB PF02233.16 OAP57518.1 - 2.4 7.0 7.2 3.2 6.6 7.2 1.1 1 0 0 1 1 1 0 NAD(P) transhydrogenase beta subunit FAA_hydrolase PF01557.18 OAP57519.1 - 6.1e-62 209.1 0.0 8.6e-62 208.6 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Abhydrolase_1 PF00561.20 OAP57519.1 - 1.2e-19 71.0 0.2 4.6e-13 49.4 0.3 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAP57519.1 - 2.7e-17 62.9 0.1 1.1e-16 60.8 0.1 2.0 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OAP57519.1 - 2.9e-13 50.9 0.2 5.4e-13 50.1 0.2 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.13 OAP57519.1 - 0.00013 21.8 0.3 0.00035 20.5 0.1 1.8 2 0 0 2 2 2 1 Serine hydrolase Abhydrolase_5 PF12695.7 OAP57519.1 - 0.0014 18.4 0.1 1.3 8.8 0.0 2.6 2 1 1 3 3 3 2 Alpha/beta hydrolase family Esterase PF00756.20 OAP57519.1 - 0.0053 16.4 0.1 0.0089 15.7 0.1 1.3 1 0 0 1 1 1 1 Putative esterase PGAP1 PF07819.13 OAP57519.1 - 0.042 13.5 0.9 0.95 9.1 0.1 2.2 1 1 0 2 2 2 0 PGAP1-like protein Abhydrolase_4 PF08386.10 OAP57519.1 - 0.077 13.1 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein Thioesterase PF00975.20 OAP57519.1 - 0.15 12.2 0.1 0.3 11.1 0.1 1.5 1 0 0 1 1 1 0 Thioesterase domain Fungal_trans PF04082.18 OAP57520.1 - 1.8e-12 46.9 0.4 3.8e-12 45.8 0.4 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP57520.1 - 7.1e-08 32.4 8.3 1.6e-07 31.3 8.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SUIM_assoc PF16619.5 OAP57520.1 - 0.012 15.6 0.7 0.012 15.6 0.7 2.2 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Dscam_C PF12355.8 OAP57520.1 - 0.64 11.0 6.4 0.27 12.2 0.4 2.4 2 0 0 2 2 2 0 Down syndrome cell adhesion molecule C terminal RPE65 PF03055.15 OAP57521.1 - 9e-124 414.2 0.0 1e-123 414.0 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein PPI_Ypi1 PF07491.11 OAP57521.1 - 0.0085 15.9 0.1 0.019 14.8 0.1 1.5 1 0 0 1 1 1 1 Protein phosphatase inhibitor SQS_PSY PF00494.19 OAP57522.1 - 6.5e-55 186.4 0.1 1.1e-54 185.7 0.1 1.3 1 0 0 1 1 1 1 Squalene/phytoene synthase Amino_oxidase PF01593.24 OAP57522.1 - 1.4e-23 83.9 0.3 1.3e-22 80.8 0.3 2.2 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OAP57522.1 - 1.6e-13 50.6 0.1 3.7e-13 49.5 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAP57522.1 - 1.6e-06 28.0 0.9 2.2e-05 24.2 1.0 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAP57522.1 - 1.1e-05 24.8 0.0 0.00056 19.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAP57522.1 - 0.00039 19.6 3.0 0.00064 18.9 1.1 2.0 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 OAP57522.1 - 0.00084 18.1 0.1 0.0097 14.6 0.4 2.0 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 OAP57522.1 - 0.0038 16.6 0.1 0.0086 15.5 0.0 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 OAP57522.1 - 0.0056 16.0 0.1 0.0089 15.3 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAP57522.1 - 0.14 11.4 0.2 0.24 10.6 0.2 1.2 1 0 0 1 1 1 0 Thi4 family FAD_binding_3 PF01494.19 OAP57522.1 - 0.19 10.9 0.3 0.34 10.1 0.3 1.3 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.22 OAP57522.1 - 0.4 9.7 1.1 0.69 8.9 1.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Bac_rhodopsin PF01036.18 OAP57523.1 - 5.5e-45 153.7 20.9 6.6e-45 153.4 20.9 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF1980 PF09323.10 OAP57523.1 - 0.94 9.4 6.1 0.14 12.0 2.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) Fungal_trans PF04082.18 OAP57525.1 - 4.9e-05 22.5 0.5 7.6e-05 21.9 0.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP57525.1 - 0.0014 18.7 2.3 0.0014 18.7 2.3 2.5 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hamartin PF04388.12 OAP57525.1 - 0.55 8.8 3.8 0.12 11.0 0.2 1.7 2 0 0 2 2 2 0 Hamartin protein Cupin_2 PF07883.11 OAP57526.1 - 1e-08 34.7 0.0 3.4e-08 33.1 0.0 1.8 2 0 0 2 2 2 1 Cupin domain Cupin_3 PF05899.12 OAP57526.1 - 0.043 13.5 0.0 0.12 12.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF861) Transp_cyt_pur PF02133.15 OAP57527.1 - 5.6e-78 262.7 41.7 6.4e-78 262.5 41.7 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF1129 PF06570.11 OAP57527.1 - 0.88 9.0 4.0 2.7 7.4 4.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) Abhydrolase_6 PF12697.7 OAP57528.1 - 2.8e-05 24.8 1.6 2.8e-05 24.8 1.6 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAP57528.1 - 0.0025 17.5 0.1 0.0069 16.1 0.1 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OAP57528.1 - 0.014 14.9 0.0 0.045 13.2 0.0 1.8 1 1 0 1 1 1 0 Prolyl oligopeptidase family AMP-binding PF00501.28 OAP57529.1 - 1.2e-40 139.5 0.0 1.7e-40 138.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 OAP57529.1 - 5.3e-07 29.4 0.1 1.3e-06 28.2 0.1 1.7 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 OAP57529.1 - 0.00045 21.1 0.0 0.001 20.0 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain MTS PF05175.14 OAP57529.1 - 0.13 11.8 0.0 0.34 10.5 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase small domain LRR_8 PF13855.6 OAP57530.1 - 5.3e-10 38.9 4.8 1.8e-09 37.2 4.8 2.0 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 OAP57530.1 - 5.2e-08 33.1 3.4 5.2e-08 33.1 3.4 3.4 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OAP57530.1 - 0.0022 18.3 5.8 3.4 8.6 0.2 3.9 3 0 0 3 3 3 2 Leucine Rich Repeat TctC PF03401.14 OAP57530.1 - 0.14 11.2 0.0 0.2 10.7 0.0 1.1 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter family receptor LRR_9 PF14580.6 OAP57530.1 - 0.14 11.6 0.8 0.27 10.7 0.8 1.4 1 0 0 1 1 1 0 Leucine-rich repeat LRR_6 PF13516.6 OAP57530.1 - 1.5 9.1 7.5 12 6.3 0.2 3.2 3 0 0 3 3 3 0 Leucine Rich repeat Efg1 PF10153.9 OAP57532.1 - 7e-30 103.7 5.8 7e-30 103.7 5.8 2.1 3 0 0 3 3 3 1 rRNA-processing protein Efg1 zinc_ribbon_16 PF17034.5 OAP57533.1 - 2.6e-19 69.7 9.7 1.6e-12 47.7 5.0 2.5 2 0 0 2 2 2 2 Zinc-ribbon like family WD40 PF00400.32 OAP57533.1 - 0.003 18.3 0.2 12 7.0 0.0 3.9 3 0 0 3 3 3 2 WD domain, G-beta repeat Zn_ribbon_17 PF17120.5 OAP57533.1 - 0.0041 16.7 10.0 0.015 14.9 10.0 2.0 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type VIT1 PF01988.19 OAP57534.1 - 0.0064 16.4 1.1 0.015 15.2 0.5 2.0 1 1 0 1 1 1 1 VIT family DUF5413 PF17434.2 OAP57534.1 - 0.012 16.0 0.2 0.043 14.1 0.2 2.0 1 0 0 1 1 1 0 Family of unknown function (DUF5413) DUF4040 PF13244.6 OAP57534.1 - 0.12 12.6 0.6 0.12 12.6 0.6 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF4040) Peptidase_A4 PF01828.17 OAP57535.1 - 2.1e-42 145.0 8.4 2.9e-42 144.5 8.4 1.2 1 0 0 1 1 1 1 Peptidase A4 family Peptidase_S3 PF00944.19 OAP57535.1 - 0.087 12.6 0.1 0.14 12.0 0.1 1.2 1 0 0 1 1 1 0 Alphavirus core protein SpaA PF17802.1 OAP57535.1 - 0.64 10.4 3.6 1.5 9.2 3.6 1.7 1 1 0 1 1 1 0 Prealbumin-like fold domain Ank_4 PF13637.6 OAP57536.1 - 9.2e-14 51.6 0.0 6.1e-09 36.2 0.0 2.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OAP57536.1 - 8.4e-12 45.5 0.0 4.8e-11 43.1 0.0 2.0 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 OAP57536.1 - 1.3e-10 41.3 0.2 0.0013 19.1 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 OAP57536.1 - 8.2e-10 38.8 0.1 1.2e-05 25.4 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAP57536.1 - 2.1e-08 33.8 0.0 0.0036 17.7 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Astacin PF01400.24 OAP57536.1 - 1.8e-06 27.7 0.2 3.2e-06 26.9 0.2 1.5 1 1 0 1 1 1 1 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.24 OAP57536.1 - 5e-05 23.2 2.2 0.0011 18.9 0.8 2.2 1 1 1 2 2 2 2 Matrixin Reprolysin_5 PF13688.6 OAP57536.1 - 0.0081 16.3 0.4 0.011 15.9 0.4 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 OAP57536.1 - 0.038 13.6 0.0 0.071 12.8 0.0 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like p450 PF00067.22 OAP57537.1 - 9.2e-52 176.3 0.0 1.1e-51 176.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 OAP57538.1 - 5.9e-16 58.3 0.0 7.5e-16 57.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Glyoxalase PF00903.25 OAP57539.1 - 5.5e-14 52.5 0.0 8.1e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 OAP57539.1 - 7.6e-05 23.5 0.0 0.00013 22.7 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase-like domain FAD_binding_3 PF01494.19 OAP57540.1 - 9e-80 268.5 0.0 1.1e-79 268.2 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 OAP57540.1 - 0.005 16.1 0.0 0.034 13.4 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAP57540.1 - 0.019 15.5 0.1 0.17 12.5 0.0 2.5 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAP57540.1 - 0.02 14.2 0.0 0.068 12.4 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAP57540.1 - 0.042 14.1 0.2 0.16 12.3 0.2 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain p450 PF00067.22 OAP57541.1 - 5.2e-83 279.3 0.0 9.9e-54 182.8 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 SnoaL_4 PF13577.6 OAP57542.1 - 0.0035 17.5 0.1 0.012 15.7 0.0 1.6 1 1 1 2 2 2 1 SnoaL-like domain DUF4440 PF14534.6 OAP57542.1 - 0.0035 17.7 0.1 0.0056 17.1 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_2 PF12680.7 OAP57542.1 - 0.01 16.5 0.2 0.014 16.0 0.2 1.2 1 0 0 1 1 1 0 SnoaL-like domain Fungal_trans PF04082.18 OAP57543.1 - 6.8e-15 54.8 0.4 3.8e-14 52.3 0.4 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain B2 PF11473.8 OAP57543.1 - 0.0029 17.3 0.0 0.0069 16.2 0.0 1.6 1 0 0 1 1 1 1 RNA binding protein B2 SARAF PF06682.12 OAP57544.1 - 1.3e-94 317.5 0.1 1.6e-94 317.3 0.1 1.0 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis Tyr-DNA_phospho PF06087.12 OAP57545.1 - 1.6e-83 281.0 0.0 2.4e-83 280.4 0.0 1.2 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase UIM PF02809.20 OAP57545.1 - 0.00052 19.8 2.6 0.00052 19.8 2.6 1.9 2 0 0 2 2 2 1 Ubiquitin interaction motif PLDc_2 PF13091.6 OAP57545.1 - 0.0037 17.1 0.0 0.015 15.1 0.0 1.9 2 0 0 2 2 2 1 PLD-like domain Gti1_Pac2 PF09729.9 OAP57546.1 - 2.9e-63 213.2 0.0 5.8e-63 212.2 0.0 1.5 1 0 0 1 1 1 1 Gti1/Pac2 family MBOAT PF03062.19 OAP57547.1 - 4e-57 194.1 4.3 7.7e-57 193.2 4.3 1.4 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Ribosomal_S7 PF00177.21 OAP57547.1 - 0.028 14.1 0.0 0.07 12.8 0.0 1.7 1 1 0 1 1 1 0 Ribosomal protein S7p/S5e PAP2 PF01569.21 OAP57547.1 - 0.055 13.2 3.7 0.16 11.7 3.7 1.8 1 0 0 1 1 1 0 PAP2 superfamily Sec1 PF00995.23 OAP57548.1 - 3.4e-133 445.9 0.1 4e-133 445.7 0.1 1.1 1 0 0 1 1 1 1 Sec1 family Glyco_tran_WecB PF03808.13 OAP57548.1 - 0.19 11.7 0.0 2.1 8.3 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family CDP-OH_P_transf PF01066.21 OAP57549.1 - 6.1e-14 52.5 0.8 6.1e-14 52.5 0.8 2.2 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase GIDA PF01134.22 OAP57550.1 - 9.8e-158 525.3 0.0 1.2e-157 525.0 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 OAP57550.1 - 3.5e-64 216.8 0.0 5.1e-64 216.3 0.0 1.2 1 0 0 1 1 1 1 GidA associated domain Pyr_redox_2 PF07992.14 OAP57550.1 - 1.5e-06 27.7 0.1 3.9e-06 26.3 0.1 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 OAP57550.1 - 2e-06 27.4 1.9 3.4e-06 26.7 1.8 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OAP57550.1 - 0.00016 20.9 1.7 0.00016 20.9 1.7 1.7 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 OAP57550.1 - 0.003 16.9 0.1 0.0064 15.8 0.1 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 OAP57550.1 - 0.0096 14.7 1.3 0.11 11.1 0.4 2.3 2 0 0 2 2 2 1 HI0933-like protein Trp_halogenase PF04820.14 OAP57550.1 - 0.17 10.7 0.5 4.2 6.1 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Ank_2 PF12796.7 OAP57551.1 - 1.7e-35 121.4 1.8 3.5e-11 43.5 0.0 4.9 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OAP57551.1 - 8.3e-21 73.8 9.7 6.6e-06 26.3 0.1 9.3 5 3 4 9 9 9 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 OAP57551.1 - 6.6e-17 61.6 4.3 5.6e-07 30.0 0.0 6.5 3 1 4 7 7 7 5 Ankyrin repeats (many copies) Ank PF00023.30 OAP57551.1 - 3.9e-15 55.5 11.3 0.0014 18.9 0.0 9.0 9 0 0 9 9 9 3 Ankyrin repeat Ank_3 PF13606.6 OAP57551.1 - 8.7e-15 53.4 7.8 0.022 15.3 0.0 9.5 9 0 0 9 9 9 3 Ankyrin repeat NACHT PF05729.12 OAP57551.1 - 4.4e-07 30.0 0.0 1.2e-06 28.5 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 OAP57551.1 - 0.028 14.8 0.3 0.47 10.8 0.0 2.9 4 0 0 4 4 4 0 AAA ATPase domain GvpL_GvpF PF06386.11 OAP57551.1 - 0.048 13.6 0.2 0.14 12.1 0.0 1.8 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF Zeta_toxin PF06414.12 OAP57551.1 - 0.057 12.7 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_22 PF13401.6 OAP57551.1 - 0.1 12.9 0.0 0.32 11.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain Torsin PF06309.11 OAP57551.1 - 0.14 12.3 0.0 0.34 11.0 0.0 1.7 1 0 0 1 1 1 0 Torsin AAA PF00004.29 OAP57551.1 - 0.18 12.2 0.0 0.63 10.5 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Anticodon_1 PF08264.13 OAP57553.1 - 1e-12 48.3 0.0 2.1e-12 47.3 0.0 1.5 1 1 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1 PF00133.22 OAP57553.1 - 9.1e-06 24.2 0.0 1.8e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 OAP57553.1 - 0.0025 16.6 0.0 0.0046 15.8 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 OAP57554.1 - 5.8e-41 140.0 0.0 9e-41 139.4 0.0 1.3 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1 PF00133.22 OAP57554.1 - 3.7e-30 104.7 0.0 2.7e-27 95.3 0.0 4.1 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 OAP57554.1 - 7.4e-23 80.9 0.1 1.2e-20 73.6 0.0 2.1 1 1 1 2 2 2 2 tRNA synthetases class I (M) DUF3425 PF11905.8 OAP57556.1 - 4.4e-23 81.6 3.4 8.8e-23 80.6 3.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 OAP57556.1 - 0.0026 17.8 8.4 0.0072 16.4 5.8 2.7 2 1 1 3 3 3 1 bZIP transcription factor YabA PF06156.13 OAP57556.1 - 0.18 12.5 0.8 0.81 10.4 0.4 2.2 2 0 0 2 2 2 0 Initiation control protein YabA bZIP_2 PF07716.15 OAP57556.1 - 0.4 10.8 9.7 0.032 14.3 3.9 2.1 2 0 0 2 2 2 0 Basic region leucine zipper BMFP PF04380.13 OAP57556.1 - 4.7 7.8 8.1 1.5 9.3 1.3 2.9 3 0 0 3 3 3 0 Membrane fusogenic activity Coatomer_E PF04733.14 OAP57557.1 - 7.5e-53 179.8 9.9 8.5e-53 179.6 9.9 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit ANAPC3 PF12895.7 OAP57557.1 - 0.0002 21.5 0.6 1.4 9.2 0.3 2.9 2 1 1 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 OAP57557.1 - 0.00021 21.8 17.9 0.0029 18.1 2.6 3.9 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 OAP57557.1 - 0.00086 19.6 5.9 0.34 11.2 0.1 3.7 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 OAP57557.1 - 0.0015 18.5 2.7 0.56 10.5 0.0 4.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_4 PF07721.14 OAP57557.1 - 0.0051 17.3 1.0 0.14 12.8 0.5 5.5 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 OAP57557.1 - 0.032 14.0 0.0 8.2 6.4 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Type_III_YscG PF09477.10 OAP57557.1 - 0.043 13.9 4.9 0.18 11.9 2.0 2.5 1 1 0 2 2 2 0 Bacterial type II secretion system chaperone protein (type_III_yscG) TPR_16 PF13432.6 OAP57557.1 - 0.18 12.5 15.9 0.32 11.7 0.1 4.6 3 1 2 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 OAP57557.1 - 0.64 11.0 16.2 8 7.6 0.1 4.8 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 OAP57557.1 - 2.8 7.9 6.6 7 6.7 0.1 4.1 4 1 0 4 4 4 0 Tetratricopeptide repeat Aldo_ket_red PF00248.21 OAP57558.1 - 6.3e-73 245.5 0.0 7.5e-73 245.3 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family ATP_transf PF09830.9 OAP57559.1 - 0.048 13.8 0.3 0.3 11.3 0.1 2.0 2 0 0 2 2 2 0 ATP adenylyltransferase MscS_TM PF12794.7 OAP57559.1 - 0.23 10.3 3.1 2.4 6.9 3.1 2.0 1 1 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Sugar_tr PF00083.24 OAP57560.1 - 1.3e-78 264.9 24.2 1.5e-78 264.7 24.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP57560.1 - 4.3e-21 75.2 47.9 4.3e-12 45.6 19.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily adh_short_C2 PF13561.6 OAP57561.1 - 7.6e-53 179.5 4.8 9.3e-53 179.2 4.8 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP57561.1 - 4.4e-43 147.0 1.3 5.9e-43 146.6 1.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAP57561.1 - 0.00062 19.7 0.7 0.001 19.0 0.7 1.3 1 0 0 1 1 1 1 KR domain SWIRM-assoc_3 PF16498.5 OAP57561.1 - 0.028 14.7 1.3 0.062 13.6 0.2 2.1 2 0 0 2 2 2 0 SWIRM-associated domain at the C-terminal TRI5 PF06330.11 OAP57562.1 - 3.9e-17 62.2 0.0 6.8e-17 61.4 0.0 1.4 1 1 0 1 1 1 1 Trichodiene synthase (TRI5) Trp_syntA PF00290.20 OAP57563.1 - 4.4e-94 314.2 0.0 8.2e-94 313.3 0.0 1.4 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.25 OAP57563.1 - 7.4e-51 173.3 1.1 1.4e-50 172.4 1.1 1.4 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme HET PF06985.11 OAP57565.1 - 1.5e-13 51.3 0.0 3.9e-13 50.0 0.0 1.8 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) DUF1989 PF09347.10 OAP57567.1 - 1.3e-63 213.6 0.0 1.7e-63 213.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) Aminotran_3 PF00202.21 OAP57568.1 - 7.6e-111 370.6 0.0 9.6e-111 370.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III DUF1674 PF07896.12 OAP57570.1 - 2.2e-19 69.6 3.4 5.9e-19 68.3 3.4 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1674) PepSY_2 PF13670.6 OAP57570.1 - 0.2 11.7 0.0 0.37 10.8 0.0 1.5 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain Inhibitor_I9 PF05922.16 OAP57571.1 - 0.00082 20.0 0.1 0.0011 19.6 0.1 1.2 1 0 0 1 1 1 1 Peptidase inhibitor I9 Glyoxalase PF00903.25 OAP57572.1 - 3.7e-15 56.2 0.0 5.4e-15 55.7 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 OAP57572.1 - 5.5e-10 39.5 0.0 8.4e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 OAP57572.1 - 0.00049 20.0 0.0 1.1 9.2 0.0 3.0 3 0 0 3 3 3 2 Glyoxalase-like domain Glyoxalase_3 PF13468.6 OAP57572.1 - 0.066 13.3 0.0 0.19 11.8 0.0 1.8 2 1 1 3 3 3 0 Glyoxalase-like domain Ubie_methyltran PF01209.18 OAP57573.1 - 1.5e-13 50.6 0.0 3.1e-13 49.6 0.0 1.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 OAP57573.1 - 4.8e-13 49.6 0.0 1.6e-12 47.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAP57573.1 - 9.1e-13 48.7 0.0 3.7e-12 46.8 0.0 2.0 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAP57573.1 - 3.1e-09 36.8 0.0 4.1e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAP57573.1 - 2.4e-06 28.2 0.0 4.4e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAP57573.1 - 0.0093 15.8 0.0 0.012 15.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain p450 PF00067.22 OAP57574.1 - 1.3e-57 195.6 0.0 1.7e-57 195.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 APAF1_C PF17908.1 OAP57574.1 - 0.15 12.1 0.1 0.44 10.6 0.0 1.7 1 1 0 1 1 1 0 APAF-1 helical domain SET PF00856.28 OAP57575.1 - 1.4e-12 48.3 0.0 2.7e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 SET domain FIST_C PF10442.9 OAP57575.1 - 0.06 13.3 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 FIST C domain Phytase-like PF13449.6 OAP57577.1 - 2.4e-38 132.7 0.0 4.2e-38 131.9 0.0 1.4 1 1 0 1 1 1 1 Esterase-like activity of phytase LVIVD PF08309.11 OAP57577.1 - 0.12 11.8 1.1 4.3 6.7 0.1 3.1 3 0 0 3 3 3 0 LVIVD repeat Grg1 PF11034.8 OAP57578.1 - 6.2e-32 109.6 12.4 7e-32 109.5 12.4 1.0 1 0 0 1 1 1 1 Glucose-repressible protein Grg1 Meckelin PF09773.9 OAP57579.1 - 0.21 9.6 0.3 0.29 9.2 0.3 1.1 1 0 0 1 1 1 0 Meckelin (Transmembrane protein 67) WD40 PF00400.32 OAP57581.1 - 3.4e-40 135.3 8.9 3e-06 27.8 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAP57581.1 - 7.7e-10 39.0 0.1 0.3 11.4 0.0 4.8 1 1 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 OAP57581.1 - 0.0044 15.8 0.1 1 8.0 0.0 2.3 2 0 0 2 2 2 2 Nup133 N terminal like Ge1_WD40 PF16529.5 OAP57581.1 - 0.11 11.4 0.0 8.6 5.2 0.0 2.6 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF5643 PF18705.1 OAP57581.1 - 0.17 11.9 0.0 20 5.2 0.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5643) TRAPP PF04051.16 OAP57582.1 - 5.6e-15 55.3 0.0 3.9e-14 52.6 0.0 1.9 1 1 1 2 2 2 1 Transport protein particle (TRAPP) component HMGL-like PF00682.19 OAP57585.1 - 6.7e-76 255.3 0.0 1.2e-75 254.5 0.0 1.4 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 OAP57585.1 - 3.1e-23 82.1 0.6 1.9e-22 79.6 0.6 2.1 1 1 0 1 1 1 1 LeuA allosteric (dimerisation) domain RAP80_UIM PF18282.1 OAP57585.1 - 0.06 13.1 0.2 4.1 7.2 0.0 3.1 3 0 0 3 3 3 0 RAP80 N-terminal ubiquitin interaction motif DAO PF01266.24 OAP57586.1 - 2.1e-51 175.6 0.1 3.5e-51 174.8 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 OAP57586.1 - 1.4e-44 151.0 0.1 2.5e-44 150.2 0.1 1.4 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 OAP57586.1 - 4.6e-09 35.9 0.9 2e-08 33.7 0.9 2.0 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 OAP57586.1 - 2.5e-05 23.8 0.6 8.4e-05 22.1 0.2 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAP57586.1 - 0.0002 20.7 0.0 0.0015 17.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAP57586.1 - 0.0026 17.9 0.3 0.008 16.4 0.2 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.18 OAP57586.1 - 0.0051 16.7 0.2 0.011 15.6 0.2 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.22 OAP57586.1 - 0.0094 15.1 0.4 0.024 13.7 0.3 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.14 OAP57586.1 - 0.039 12.7 0.4 0.066 11.9 0.4 1.3 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.27 OAP57586.1 - 0.04 14.5 0.5 0.18 12.4 0.1 2.3 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAP57586.1 - 0.053 12.8 1.1 2.8 7.1 0.2 2.3 2 0 0 2 2 2 0 Thi4 family FAD_binding_3 PF01494.19 OAP57586.1 - 0.12 11.6 0.2 0.5 9.6 0.2 2.0 1 1 0 1 1 1 0 FAD binding domain Aa_trans PF01490.18 OAP57587.1 - 1e-45 156.2 33.0 1.2e-45 156.0 33.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 OAP57587.1 - 0.0059 15.7 17.4 0.0059 15.7 17.4 2.4 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family FAD_binding_3 PF01494.19 OAP57588.1 - 3.1e-20 72.7 0.0 1.9e-19 70.2 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAP57588.1 - 1.2e-07 31.7 3.7 0.0043 16.7 5.2 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAP57588.1 - 1.3e-07 31.2 0.2 1.7e-06 27.5 0.2 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAP57588.1 - 1.9e-07 31.2 0.4 4.8e-07 29.9 0.4 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 OAP57588.1 - 3.6e-07 29.9 0.0 5e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OAP57588.1 - 7.1e-06 25.4 4.6 1.2e-05 24.6 4.6 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 OAP57588.1 - 8.5e-06 26.2 0.2 0.0021 18.6 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAP57588.1 - 2e-05 23.5 0.3 0.00058 18.7 1.0 2.1 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 OAP57588.1 - 0.0011 18.2 1.2 0.0019 17.5 1.2 1.3 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 OAP57588.1 - 0.0027 16.9 4.6 0.0049 16.0 4.6 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 OAP57588.1 - 0.0048 16.2 0.4 0.025 13.8 0.4 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 OAP57588.1 - 0.0082 15.0 2.5 3.1 6.6 0.0 2.1 1 1 0 2 2 2 2 Tryptophan halogenase AlaDh_PNT_C PF01262.21 OAP57588.1 - 0.035 13.4 1.8 0.058 12.7 1.8 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Amino_oxidase PF01593.24 OAP57588.1 - 0.085 12.1 0.3 0.89 8.8 0.3 2.4 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase MCRA PF06100.11 OAP57588.1 - 0.099 11.4 0.2 0.18 10.6 0.2 1.4 1 0 0 1 1 1 0 MCRA family UDPG_MGDP_dh_N PF03721.14 OAP57588.1 - 0.14 11.7 0.3 0.25 10.9 0.3 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain SE PF08491.10 OAP57588.1 - 0.18 10.8 0.0 0.26 10.3 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase Rossmann-like PF10727.9 OAP57588.1 - 0.27 11.1 1.4 0.56 10.1 0.5 2.0 2 0 0 2 2 2 0 Rossmann-like domain 3HCDH_N PF02737.18 OAP57588.1 - 0.3 11.0 1.5 0.54 10.1 1.5 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 OAP57588.1 - 0.3 10.1 0.8 1.5 7.8 1.5 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein bZIP_1 PF00170.21 OAP57590.1 - 5.5e-07 29.6 10.3 5.5e-07 29.6 10.3 1.8 1 1 1 2 2 2 1 bZIP transcription factor SlyX PF04102.12 OAP57590.1 - 5.8e-06 26.8 3.6 5.8e-06 26.8 3.6 1.6 1 1 1 2 2 2 1 SlyX bZIP_2 PF07716.15 OAP57590.1 - 5.5e-05 23.2 17.6 0.00015 21.8 10.1 2.1 1 1 1 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 OAP57590.1 - 0.00049 20.6 10.5 0.00051 20.5 9.6 1.5 2 0 0 2 2 1 1 bZIP Maf transcription factor DUF2353 PF09789.9 OAP57590.1 - 0.0034 16.8 2.8 0.004 16.6 2.8 1.1 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) Tup_N PF08581.10 OAP57590.1 - 0.0046 17.2 1.0 0.0085 16.4 1.0 1.4 1 0 0 1 1 1 1 Tup N-terminal Shugoshin_N PF07558.11 OAP57590.1 - 0.0047 16.8 1.6 0.24 11.3 0.3 2.3 2 0 0 2 2 2 1 Shugoshin N-terminal coiled-coil region KASH_CCD PF14662.6 OAP57590.1 - 0.021 14.6 4.6 0.026 14.3 4.6 1.1 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Spc29 PF17082.5 OAP57590.1 - 0.032 14.1 0.4 0.052 13.4 0.4 1.4 1 1 0 1 1 1 0 Spindle Pole Component 29 Spc7 PF08317.11 OAP57590.1 - 0.033 13.1 5.6 0.043 12.7 5.6 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein RPAP3_C PF13877.6 OAP57590.1 - 0.048 14.2 0.5 0.63 10.6 0.0 2.1 1 1 1 2 2 2 0 Potential Monad-binding region of RPAP3 WD40_alt PF14077.6 OAP57590.1 - 0.051 13.4 1.7 0.42 10.5 0.0 2.3 1 1 1 2 2 2 0 Alternative WD40 repeat motif Herpes_UL25 PF01499.16 OAP57590.1 - 0.056 12.0 4.3 0.068 11.7 4.3 1.0 1 0 0 1 1 1 0 Herpesvirus UL25 family SF1-HH PF16275.5 OAP57590.1 - 0.062 13.7 0.5 0.062 13.7 0.5 1.6 1 1 1 2 2 2 0 Splicing factor 1 helix-hairpin domain CHD5 PF04420.14 OAP57590.1 - 0.086 12.7 2.1 0.12 12.2 2.1 1.3 1 0 0 1 1 1 0 CHD5-like protein H-kinase_dim PF02895.14 OAP57590.1 - 0.12 12.8 0.8 0.12 12.8 0.8 2.1 2 1 1 3 3 2 0 Signal transducing histidine kinase, homodimeric domain Fib_alpha PF08702.10 OAP57590.1 - 0.13 12.4 2.0 0.17 12.0 2.0 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Troponin PF00992.20 OAP57590.1 - 1 9.7 7.9 1.4 9.2 7.9 1.2 1 0 0 1 1 1 0 Troponin DivIC PF04977.15 OAP57590.1 - 6.8 6.5 8.8 1.9 8.3 2.1 2.2 1 1 1 2 2 2 0 Septum formation initiator Fungal_trans_2 PF11951.8 OAP57591.1 - 0.0078 15.1 0.1 0.18 10.6 0.0 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain DMRT-like PF15791.5 OAP57591.1 - 0.061 13.7 0.7 0.12 12.8 0.7 1.5 1 0 0 1 1 1 0 Doublesex-and mab-3-related transcription factor C1 and C2 BRO1 PF03097.18 OAP57592.1 - 9e-116 386.9 0.2 4.2e-115 384.7 0.0 2.0 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 OAP57592.1 - 7.6e-86 288.0 12.3 1.7e-85 286.9 12.3 1.6 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV Aldolase_II PF00596.21 OAP57593.1 - 9.3e-51 172.4 0.6 1.2e-50 172.0 0.6 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain BRCC36_C PF18110.1 OAP57593.1 - 0.064 13.4 0.5 0.18 12.0 0.1 1.9 2 0 0 2 2 2 0 BRCC36 C-terminal helical domain PTPS_related PF10131.9 OAP57594.1 - 0.039 12.3 0.0 0.045 12.1 0.0 1.0 1 0 0 1 1 1 0 6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein Ferric_reduct PF01794.19 OAP57595.1 - 1.2e-20 73.9 11.3 1.2e-20 73.9 11.3 2.0 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 OAP57595.1 - 6.7e-13 49.1 0.1 1.4e-07 31.8 0.0 2.4 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 OAP57595.1 - 2e-11 43.9 0.0 1.7e-06 28.1 0.0 2.3 2 0 0 2 2 2 2 FAD-binding domain ADH_N PF08240.12 OAP57596.1 - 4.9e-05 23.2 0.0 0.00059 19.7 0.0 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAP57596.1 - 0.08 12.9 0.0 0.21 11.5 0.0 1.8 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Ank_2 PF12796.7 OAP57597.1 - 1.2e-34 118.7 0.0 2.9e-14 53.4 0.0 5.5 3 1 2 5 5 5 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAP57597.1 - 5.8e-27 93.7 0.0 1.6e-07 31.7 0.0 6.0 5 1 1 6 6 6 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 OAP57597.1 - 7e-24 83.6 0.1 8.7e-07 29.1 0.0 5.1 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAP57597.1 - 7e-23 78.2 0.0 0.0013 19.1 0.0 7.8 7 0 0 7 7 7 5 Ankyrin repeat Ank PF00023.30 OAP57597.1 - 9.4e-20 70.1 0.1 0.00019 21.7 0.0 7.1 7 0 0 7 7 7 3 Ankyrin repeat NACHT PF05729.12 OAP57597.1 - 0.0038 17.2 0.0 0.01 15.8 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 OAP57597.1 - 0.058 13.8 0.0 0.25 11.7 0.0 2.1 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 OAP57597.1 - 0.11 12.7 0.0 0.28 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain MFS_1 PF07690.16 OAP57598.1 - 1.8e-51 175.2 53.7 2.6e-51 174.6 53.2 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily AA_permease_C PF13906.6 OAP57598.1 - 0.067 13.3 0.7 0.067 13.3 0.7 3.9 4 0 0 4 4 4 0 C-terminus of AA_permease Ank_2 PF12796.7 OAP57599.1 - 5.5e-11 42.9 0.1 1.7e-05 25.3 0.1 1.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OAP57599.1 - 4.7e-08 32.7 0.1 0.047 14.3 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 OAP57599.1 - 6.8e-08 32.6 0.1 0.27 11.6 0.1 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 OAP57599.1 - 0.0016 19.0 0.0 0.0052 17.3 0.0 1.8 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 OAP57599.1 - 0.0049 17.2 0.0 1.9 9.1 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat GAT PF03127.14 OAP57599.1 - 0.0066 16.7 0.1 0.032 14.5 0.0 1.9 2 0 0 2 2 2 1 GAT domain Imm30 PF15565.6 OAP57599.1 - 0.029 14.5 0.3 0.063 13.3 0.3 1.6 1 0 0 1 1 1 0 Immunity protein 30 HTH_40 PF14493.6 OAP57599.1 - 0.1 13.0 0.0 0.19 12.2 0.0 1.5 1 1 0 1 1 1 0 Helix-turn-helix domain GTP_EFTU PF00009.27 OAP57600.1 - 6.2e-55 185.8 0.0 9.4e-55 185.2 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 OAP57600.1 - 4e-42 143.1 0.1 1.2e-41 141.5 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 OAP57600.1 - 3.6e-14 52.9 1.6 3.6e-14 52.9 1.6 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 TFIIS_C PF01096.18 OAP57600.1 - 3.5e-11 42.8 0.2 3.5e-11 42.8 0.2 2.3 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 OAP57600.1 - 0.00047 20.0 3.3 0.0016 18.2 3.3 1.9 1 1 0 1 1 1 1 RNA polymerases M/15 Kd subunit MMR_HSR1 PF01926.23 OAP57600.1 - 0.0014 18.7 0.1 0.027 14.5 0.1 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 OAP57600.1 - 5.9 6.9 7.4 0.4 10.6 1.0 2.3 3 0 0 3 3 3 0 Elongation factor Tu domain 4 adh_short_C2 PF13561.6 OAP57601.1 - 1.4e-49 168.8 0.0 1.6e-49 168.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP57601.1 - 6.5e-37 126.9 0.0 1.2e-36 126.0 0.0 1.4 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 OAP57601.1 - 3.6e-05 23.8 0.2 9.1e-05 22.4 0.2 1.7 1 1 0 1 1 1 1 KR domain Annexin PF00191.20 OAP57602.1 - 3.1e-17 62.4 0.1 0.00092 19.2 0.1 4.5 4 0 0 4 4 4 4 Annexin ArgoL1 PF08699.10 OAP57602.1 - 0.14 11.8 0.0 0.33 10.6 0.0 1.6 1 0 0 1 1 1 0 Argonaute linker 1 domain ABC1 PF03109.16 OAP57603.1 - 2e-22 79.6 0.0 4.7e-22 78.4 0.0 1.6 1 0 0 1 1 1 1 ABC1 family CobW_C PF07683.14 OAP57603.1 - 0.043 13.7 0.1 0.22 11.5 0.0 2.2 2 0 0 2 2 2 0 Cobalamin synthesis protein cobW C-terminal domain BSP_II PF05432.11 OAP57604.1 - 0.85 9.3 14.6 1.3 8.6 14.6 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Ribosomal_60s PF00428.19 OAP57604.1 - 9.3 6.9 10.3 0.75 10.4 4.9 1.9 2 0 0 2 2 2 0 60s Acidic ribosomal protein His_Phos_1 PF00300.22 OAP57605.1 - 3.1e-10 40.1 0.0 9.9e-10 38.4 0.0 1.9 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Glyco_transf_25 PF01755.17 OAP57605.1 - 0.015 15.1 0.0 0.039 13.8 0.0 1.7 1 1 0 1 1 1 0 Glycosyltransferase family 25 (LPS biosynthesis protein) APH PF01636.23 OAP57606.1 - 0.00018 21.5 0.5 0.00036 20.5 0.5 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF347 PF03988.12 OAP57607.1 - 0.15 12.3 5.1 0.091 13.0 3.2 1.7 1 1 1 2 2 2 0 Repeat of Unknown Function (DUF347) SKG6 PF08693.10 OAP57607.1 - 1.5 8.3 4.2 0.3 10.5 0.3 1.9 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Nucleoside_tran PF01733.18 OAP57608.1 - 4e-52 177.5 3.9 7e-52 176.7 3.9 1.3 1 0 0 1 1 1 1 Nucleoside transporter MFS_1 PF07690.16 OAP57608.1 - 1.1e-10 41.0 26.7 0.0011 18.0 3.7 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily PNTB PF02233.16 OAP57608.1 - 0.07 12.0 3.0 0.13 11.1 3.0 1.4 1 0 0 1 1 1 0 NAD(P) transhydrogenase beta subunit Haspin_kinase PF12330.8 OAP57609.1 - 9.4e-32 110.4 0.0 1.3e-31 109.9 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Vps62 PF06101.11 OAP57611.1 - 4.5e-17 61.6 4.5 4.9e-14 51.5 0.8 2.6 2 1 1 3 3 3 2 Vacuolar protein sorting-associated protein 62 HMG_box PF00505.19 OAP57614.1 - 0.00011 22.6 0.6 0.00021 21.6 0.6 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box PLN_propep PF16485.5 OAP57614.1 - 0.29 10.9 1.7 6.1 6.6 0.4 2.4 2 0 0 2 2 2 0 Protealysin propeptide Cpn60_TCP1 PF00118.24 OAP57615.1 - 9.5e-151 502.8 9.7 1.1e-150 502.6 9.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family RXT2_N PF08595.11 OAP57615.1 - 0.0017 18.4 5.4 0.004 17.2 5.4 1.5 1 0 0 1 1 1 1 RXT2-like, N-terminal FAM176 PF14851.6 OAP57615.1 - 0.027 14.2 4.6 0.066 12.9 4.6 1.6 1 0 0 1 1 1 0 FAM176 family PPP4R2 PF09184.11 OAP57615.1 - 0.035 13.7 4.7 0.043 13.4 3.6 1.7 2 0 0 2 2 2 0 PPP4R2 TetR_C_14 PF17754.1 OAP57615.1 - 0.076 13.0 0.7 5.8 6.9 0.1 2.5 2 0 0 2 2 2 0 MftR C-terminal domain Pox_Ag35 PF03286.14 OAP57615.1 - 0.097 12.4 8.2 0.028 14.2 4.7 1.8 2 0 0 2 2 2 0 Pox virus Ag35 surface protein MRNIP PF15749.5 OAP57615.1 - 0.098 13.4 1.6 0.19 12.4 1.6 1.5 1 0 0 1 1 1 0 MRN-interacting protein TFB6 PF17110.5 OAP57615.1 - 0.12 12.2 3.8 0.35 10.6 3.8 1.8 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH NOA36 PF06524.12 OAP57615.1 - 0.25 10.6 13.9 0.42 9.9 13.9 1.2 1 0 0 1 1 1 0 NOA36 protein Sporozoite_P67 PF05642.11 OAP57615.1 - 0.44 8.6 6.6 0.7 7.9 6.6 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Sigma70_ner PF04546.13 OAP57615.1 - 0.45 10.4 9.0 0.1 12.4 4.6 1.9 2 0 0 2 2 2 0 Sigma-70, non-essential region Nop14 PF04147.12 OAP57615.1 - 1 7.5 10.3 1.5 7.0 10.3 1.1 1 0 0 1 1 1 0 Nop14-like family FYDLN_acid PF09538.10 OAP57615.1 - 1.5 9.6 12.0 4.1 8.1 12.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Nucleo_P87 PF07267.11 OAP57615.1 - 1.6 7.5 5.7 0.66 8.8 2.9 1.7 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 RRN3 PF05327.11 OAP57615.1 - 1.6 7.2 5.6 2.4 6.6 5.6 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Afi1 PF07792.12 OAP57615.1 - 1.7 9.1 6.3 3.9 8.0 6.3 1.5 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DNA_pol_phi PF04931.13 OAP57615.1 - 1.8 6.6 15.5 3.6 5.6 15.5 1.4 1 0 0 1 1 1 0 DNA polymerase phi Cwf_Cwc_15 PF04889.12 OAP57615.1 - 3.5 7.3 12.9 5.9 6.5 12.9 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Pes-10 PF07149.11 OAP57615.1 - 4 6.4 8.3 9.1 5.2 8.3 1.6 1 0 0 1 1 1 0 Pes-10 DUF2457 PF10446.9 OAP57615.1 - 4.2 6.4 17.4 6.9 5.7 17.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Astro_capsid_p PF12226.8 OAP57615.1 - 4.8 6.2 11.8 7.8 5.5 11.8 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein PBP1_TM PF14812.6 OAP57615.1 - 6 7.3 13.0 13 6.2 13.0 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Aminotran_3 PF00202.21 OAP57616.1 - 1.5e-86 290.6 0.0 1.9e-86 290.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III DHDPS PF00701.22 OAP57617.1 - 5.6e-38 130.3 0.0 6.8e-38 130.0 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family p450 PF00067.22 OAP57618.1 - 3.4e-43 148.1 0.0 4.4e-43 147.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SSF PF00474.17 OAP57619.1 - 4e-16 58.9 32.0 6.3e-16 58.2 31.7 1.5 1 1 0 1 1 1 1 Sodium:solute symporter family adh_short PF00106.25 OAP57620.1 - 5.4e-31 107.6 0.0 6.8e-31 107.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP57620.1 - 3.2e-24 85.8 0.0 3.7e-24 85.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP57620.1 - 1.5e-09 38.0 0.1 2.2e-09 37.5 0.1 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 OAP57620.1 - 0.021 14.7 0.4 0.035 14.0 0.5 1.4 1 1 0 1 1 1 0 NAD(P)H-binding Polysacc_synt_2 PF02719.15 OAP57620.1 - 0.033 13.3 0.4 0.12 11.5 0.4 1.8 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein Fungal_trans PF04082.18 OAP57621.1 - 7.9e-13 48.0 0.5 1.1e-12 47.5 0.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DOCK_N PF16172.5 OAP57621.1 - 0.15 11.0 0.0 0.27 10.1 0.0 1.3 1 0 0 1 1 1 0 DOCK N-terminus zf-AD PF07776.15 OAP57621.1 - 0.31 11.3 1.7 5.5 7.3 0.2 2.6 2 0 0 2 2 2 0 Zinc-finger associated domain (zf-AD) Fungal_trans PF04082.18 OAP57622.1 - 1.4e-17 63.6 1.0 2.5e-17 62.8 1.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain AAT PF03417.16 OAP57623.1 - 7.3e-27 94.5 0.0 9.9e-27 94.1 0.0 1.1 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Penicil_amidase PF01804.18 OAP57623.1 - 0.013 14.5 0.0 0.018 14.1 0.0 1.2 1 0 0 1 1 1 0 Penicillin amidase Amidohydro_1 PF01979.20 OAP57624.1 - 1e-24 87.6 0.0 1.2e-22 80.7 0.0 2.1 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 OAP57624.1 - 7.3e-14 52.1 3.6 3.5e-07 30.1 0.1 3.0 2 1 0 2 2 2 2 Amidohydrolase family Aldo_ket_red PF00248.21 OAP57625.1 - 1.8e-38 132.4 0.0 9.3e-37 126.8 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Aminotran_3 PF00202.21 OAP57626.1 - 1.6e-91 307.0 0.0 2.2e-91 306.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III p450 PF00067.22 OAP57626.1 - 8.1e-47 160.0 0.0 1.2e-46 159.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Beta_elim_lyase PF01212.21 OAP57626.1 - 5.2e-05 22.7 0.0 8.8e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 OAP57626.1 - 0.2 10.8 0.0 0.71 9.0 0.0 2.0 2 1 0 2 2 2 0 Aminotransferase class I and II Amidase PF01425.21 OAP57627.1 - 1.4e-103 347.3 0.0 1.8e-103 347.0 0.0 1.1 1 0 0 1 1 1 1 Amidase MFS_1 PF07690.16 OAP57628.1 - 3.8e-33 114.9 28.7 5.1e-33 114.5 28.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 OAP57628.1 - 0.002 17.5 18.9 0.027 13.8 18.9 2.1 1 1 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB CrgA PF06781.12 OAP57628.1 - 0.54 10.4 4.9 1.3 9.1 0.5 3.7 5 0 0 5 5 5 0 Cell division protein CrgA Voltage_CLC PF00654.20 OAP57629.1 - 3.7e-86 289.6 33.2 3.2e-85 286.5 32.5 2.0 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 OAP57629.1 - 0.021 15.3 0.0 3.3 8.2 0.0 2.5 2 0 0 2 2 2 0 CBS domain PH_10 PF15411.6 OAP57630.1 - 2.9e-25 88.9 0.1 5.1e-25 88.1 0.1 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain VWA PF00092.28 OAP57630.1 - 1.6e-13 51.3 0.0 2.7e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 OAP57630.1 - 1.5e-06 28.2 0.1 1e-05 25.5 0.1 2.3 1 1 0 1 1 1 1 von Willebrand factor type A domain zf-RING_2 PF13639.6 OAP57630.1 - 7.2e-05 23.0 3.0 0.00014 22.2 3.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 OAP57630.1 - 0.00044 20.1 3.8 0.00087 19.2 3.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 OAP57630.1 - 0.00088 18.8 3.0 0.0017 18.0 3.0 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_2 PF13923.6 OAP57630.1 - 0.00097 18.9 3.3 0.0021 17.9 3.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.11 OAP57630.1 - 0.0011 19.3 3.9 0.0019 18.5 3.9 1.4 1 0 0 1 1 1 1 RING-like domain zf-C3HC4 PF00097.25 OAP57630.1 - 0.0017 18.2 3.3 0.0034 17.2 3.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OAP57630.1 - 0.019 15.2 1.3 0.046 14.0 1.3 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain PH PF00169.29 OAP57630.1 - 0.035 14.6 0.0 0.081 13.4 0.0 1.6 1 0 0 1 1 1 0 PH domain Prok-RING_4 PF14447.6 OAP57630.1 - 0.29 11.0 2.4 0.52 10.2 2.4 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 OAP57630.1 - 0.76 9.9 3.4 1.8 8.6 3.4 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3H2C3 PF17122.5 OAP57630.1 - 0.76 9.9 4.0 1.9 8.6 4.0 1.7 1 1 0 1 1 1 0 Zinc-finger AAA_5 PF07728.14 OAP57631.1 - 2.9e-124 409.5 0.0 2.3e-22 79.5 0.0 9.6 9 0 0 9 9 9 9 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 OAP57631.1 - 2.6e-42 143.3 2.7 1.9e-15 57.0 0.0 5.6 5 0 0 5 5 4 4 Midasin AAA lid domain AAA_3 PF07726.11 OAP57631.1 - 1.8e-31 108.7 0.0 4e-12 46.1 0.0 7.5 7 0 0 7 7 7 3 ATPase family associated with various cellular activities (AAA) AAA_lid_5 PF17865.1 OAP57631.1 - 7.7e-29 99.9 0.7 2.6e-28 98.2 0.2 2.3 2 0 0 2 2 1 1 Midasin AAA lid domain AAA PF00004.29 OAP57631.1 - 5.9e-28 97.9 0.0 4.7e-05 23.8 0.0 7.2 7 0 0 7 7 6 5 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 OAP57631.1 - 1.5e-26 93.0 1.8 6.1e-05 22.6 0.0 7.0 7 0 0 7 7 7 6 P-loop containing dynein motor region AAA_16 PF13191.6 OAP57631.1 - 9.8e-24 84.6 21.1 0.00036 21.0 0.1 9.6 10 2 0 10 10 6 6 AAA ATPase domain AAA_6 PF12774.7 OAP57631.1 - 7.8e-21 74.4 0.3 0.014 14.4 0.0 7.8 9 0 0 9 9 8 5 Hydrolytic ATP binding site of dynein motor region Dynein_heavy PF03028.15 OAP57631.1 - 1e-20 74.0 0.0 0.0006 19.9 0.0 7.3 7 0 0 7 7 6 4 Dynein heavy chain region D6 P-loop domain TsaE PF02367.17 OAP57631.1 - 2.3e-18 66.4 0.4 0.039 13.9 0.0 6.5 6 0 0 6 6 6 4 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 OAP57631.1 - 1.6e-16 60.4 0.0 0.027 14.2 0.0 7.0 7 0 0 7 7 7 3 Sigma-54 interaction domain AAA_22 PF13401.6 OAP57631.1 - 3.9e-15 56.3 0.0 0.088 13.1 0.0 7.4 6 0 0 6 6 6 2 AAA domain AAA_18 PF13238.6 OAP57631.1 - 4e-15 56.5 15.1 0.00038 21.0 0.0 8.0 8 0 0 8 8 6 4 AAA domain AAA_14 PF13173.6 OAP57631.1 - 3.1e-13 49.9 0.0 0.17 11.9 0.0 7.7 8 0 0 8 8 7 2 AAA domain AAA_33 PF13671.6 OAP57631.1 - 3.9e-13 49.8 0.1 0.027 14.6 0.0 7.0 6 0 0 6 6 6 2 AAA domain ABC_tran PF00005.27 OAP57631.1 - 5.1e-13 49.7 0.7 0.062 13.8 0.0 6.4 6 0 0 6 6 6 3 ABC transporter AAA_30 PF13604.6 OAP57631.1 - 7.1e-13 48.7 0.0 0.56 9.9 0.0 7.0 6 1 0 6 6 6 3 AAA domain T2SSE PF00437.20 OAP57631.1 - 4.8e-12 45.5 1.9 0.34 9.9 0.0 6.4 6 0 0 6 6 6 2 Type II/IV secretion system protein NACHT PF05729.12 OAP57631.1 - 9.2e-12 45.2 4.2 0.041 13.8 0.1 6.0 6 0 0 6 6 5 3 NACHT domain Zeta_toxin PF06414.12 OAP57631.1 - 1.5e-11 44.0 0.4 0.76 9.0 0.0 7.7 7 0 0 7 7 7 2 Zeta toxin Mg_chelatase PF01078.21 OAP57631.1 - 1.6e-11 44.0 1.7 3.4 7.0 0.0 8.7 8 2 1 9 9 9 0 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 OAP57631.1 - 2.8e-11 43.4 0.2 0.48 10.2 0.0 6.3 6 0 0 6 6 6 2 Holliday junction DNA helicase RuvB P-loop domain RsgA_GTPase PF03193.16 OAP57631.1 - 4e-11 43.1 1.1 0.043 13.7 0.0 5.6 6 0 0 6 6 6 2 RsgA GTPase RNA_helicase PF00910.22 OAP57631.1 - 6.3e-11 42.6 0.9 4 7.9 0.0 6.6 6 0 0 6 6 6 0 RNA helicase Sigma54_activ_2 PF14532.6 OAP57631.1 - 1.2e-10 41.6 1.1 0.038 14.1 0.0 6.7 6 0 0 6 6 6 1 Sigma-54 interaction domain AAA_29 PF13555.6 OAP57631.1 - 3.1e-09 36.4 0.6 0.69 9.7 0.0 6.3 6 0 0 6 6 6 2 P-loop containing region of AAA domain AAA_19 PF13245.6 OAP57631.1 - 7.8e-09 36.0 7.2 3.6 7.9 0.1 7.1 6 0 0 6 6 6 0 AAA domain AAA_28 PF13521.6 OAP57631.1 - 7.8e-09 36.0 3.6 0.019 15.2 0.0 6.5 6 0 0 6 6 6 1 AAA domain IstB_IS21 PF01695.17 OAP57631.1 - 1.6e-08 34.5 0.1 0.62 9.8 0.0 5.5 5 0 0 5 5 5 1 IstB-like ATP binding protein Rad17 PF03215.15 OAP57631.1 - 5e-07 29.8 0.2 0.7 9.8 0.0 5.2 5 0 0 5 5 5 1 Rad17 P-loop domain PduV-EutP PF10662.9 OAP57631.1 - 5.1e-07 29.5 1.6 0.7 9.6 0.0 5.5 6 0 0 6 6 5 1 Ethanolamine utilisation - propanediol utilisation AAA_25 PF13481.6 OAP57631.1 - 8.3e-07 28.8 4.9 0.89 9.1 0.1 5.4 6 0 0 6 6 4 1 AAA domain NTPase_1 PF03266.15 OAP57631.1 - 2.3e-06 27.6 4.6 2.3 8.1 0.3 5.6 5 0 0 5 5 5 1 NTPase Roc PF08477.13 OAP57631.1 - 2.7e-06 27.6 2.7 3.5 7.9 0.2 6.2 6 0 0 6 6 6 0 Ras of Complex, Roc, domain of DAPkinase ATPase_2 PF01637.18 OAP57631.1 - 3.2e-06 27.2 0.0 4.1 7.3 0.0 5.5 6 0 0 6 6 5 0 ATPase domain predominantly from Archaea TIP49 PF06068.13 OAP57631.1 - 3.4e-06 26.5 0.9 0.017 14.3 0.0 5.0 6 0 0 6 6 6 1 TIP49 P-loop domain DUF815 PF05673.13 OAP57631.1 - 4.4e-06 26.0 0.4 1 8.5 0.0 5.3 6 0 0 6 6 6 1 Protein of unknown function (DUF815) TniB PF05621.11 OAP57631.1 - 2.4e-05 23.8 0.0 17 4.7 0.0 5.8 6 0 0 6 6 6 0 Bacterial TniB protein AAA_24 PF13479.6 OAP57631.1 - 2.9e-05 23.9 0.1 1.3 8.7 0.0 5.3 6 0 0 6 6 6 1 AAA domain CPT PF07931.12 OAP57631.1 - 8.1e-05 22.5 1.6 2 8.2 0.0 5.8 5 1 0 5 5 5 1 Chloramphenicol phosphotransferase-like protein CbiA PF01656.23 OAP57631.1 - 0.00014 21.9 0.1 1.6 8.8 0.0 4.4 4 0 0 4 4 3 1 CobQ/CobB/MinD/ParA nucleotide binding domain PhoH PF02562.16 OAP57631.1 - 0.0003 20.3 1.2 2.2 7.7 0.0 4.2 4 0 0 4 4 4 1 PhoH-like protein SRP54 PF00448.22 OAP57631.1 - 0.00054 19.6 2.7 7.8 6.1 0.1 5.0 5 0 0 5 5 5 0 SRP54-type protein, GTPase domain cobW PF02492.19 OAP57631.1 - 0.00055 19.6 3.4 1.1 8.8 0.0 4.9 5 0 0 5 5 5 1 CobW/HypB/UreG, nucleotide-binding domain Bac_DnaA PF00308.18 OAP57631.1 - 0.00075 19.4 0.0 6.1 6.6 0.0 4.6 5 0 0 5 5 4 0 Bacterial dnaA protein MMR_HSR1 PF01926.23 OAP57631.1 - 0.002 18.2 2.2 26 4.9 0.0 6.0 7 0 0 7 7 5 0 50S ribosome-binding GTPase SRPRB PF09439.10 OAP57631.1 - 0.0022 17.4 1.2 5.6 6.3 0.0 5.3 6 0 0 6 6 6 0 Signal recognition particle receptor beta subunit AAA_8 PF12780.7 OAP57631.1 - 0.0043 16.4 0.5 34 3.6 0.0 5.6 6 0 0 6 6 5 0 P-loop containing dynein motor region D4 ResIII PF04851.15 OAP57631.1 - 0.0051 16.8 1.2 21 5.0 0.0 5.0 5 0 0 5 5 4 0 Type III restriction enzyme, res subunit NB-ARC PF00931.22 OAP57631.1 - 0.0054 16.0 0.2 16 4.6 0.0 4.5 5 0 0 5 5 5 0 NB-ARC domain HCV_NS4b PF01001.19 OAP57631.1 - 0.0073 15.9 0.0 1.5 8.4 0.0 2.5 2 0 0 2 2 2 1 Hepatitis C virus non-structural protein NS4b dNK PF01712.19 OAP57631.1 - 0.0087 15.9 5.3 17 5.2 0.0 5.4 6 0 0 6 6 5 0 Deoxynucleoside kinase AAA_21 PF13304.6 OAP57631.1 - 0.022 14.6 0.0 0.57 9.9 0.0 3.2 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system ATP_bind_1 PF03029.17 OAP57631.1 - 0.076 12.8 10.7 2.6 7.8 0.1 5.4 6 0 0 6 6 5 0 Conserved hypothetical ATP binding protein Cytidylate_kin PF02224.18 OAP57631.1 - 0.084 12.6 0.1 3 7.5 0.0 3.3 2 0 0 2 2 2 0 Cytidylate kinase Septin PF00735.18 OAP57631.1 - 0.19 10.9 0.4 27 3.9 0.0 3.3 3 0 0 3 3 3 0 Septin ATPase PF06745.13 OAP57631.1 - 0.22 10.9 0.6 52 3.1 0.0 4.4 5 0 0 5 5 5 0 KaiC AAA_23 PF13476.6 OAP57631.1 - 1.6 9.2 0.0 1.6 9.2 0.0 7.1 7 1 0 7 7 6 0 AAA domain MobB PF03205.14 OAP57631.1 - 5.6 6.9 6.8 49 3.8 0.0 4.5 6 0 0 6 6 3 0 Molybdopterin guanine dinucleotide synthesis protein B PRCC PF10253.9 OAP57633.1 - 1.7e-36 127.1 8.3 1.7e-36 127.1 8.3 2.4 1 1 1 2 2 2 1 Mitotic checkpoint regulator, MAD2B-interacting Peptidase_M48 PF01435.18 OAP57634.1 - 2.6e-33 115.5 0.0 4e-33 114.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M48 adh_short_C2 PF13561.6 OAP57635.1 - 4.4e-58 196.6 0.0 2.3e-56 191.0 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP57635.1 - 1.3e-39 135.7 0.0 3.7e-39 134.2 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAP57635.1 - 1.8e-12 47.5 0.0 2.7e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAP57635.1 - 0.0071 15.8 0.0 0.021 14.3 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 OAP57635.1 - 0.071 12.2 0.0 0.1 11.7 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Fungal_trans PF04082.18 OAP57636.1 - 2.8e-11 43.0 0.8 5.3e-11 42.0 0.8 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP57636.1 - 1.5e-05 25.0 13.2 2.5e-05 24.3 13.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain EBP PF05241.12 OAP57637.1 - 5.4e-64 214.9 3.8 6.4e-64 214.7 3.8 1.0 1 0 0 1 1 1 1 Emopamil binding protein Acetyltransf_7 PF13508.7 OAP57638.1 - 8e-09 35.8 0.0 1.3e-08 35.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAP57638.1 - 1.7e-08 34.7 0.0 6.7e-08 32.8 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OAP57638.1 - 1.4e-06 28.3 0.0 2.6e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 OAP57638.1 - 0.002 18.2 0.0 0.0054 16.8 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain SgrT PF15894.5 OAP57638.1 - 0.11 12.5 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Inhibitor of glucose uptake transporter SgrT Sugar_tr PF00083.24 OAP57639.1 - 9.1e-108 361.0 19.7 1.1e-107 360.8 19.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP57639.1 - 4.1e-26 91.7 30.7 3.1e-25 88.8 24.7 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily zf-C3HC4 PF00097.25 OAP57640.1 - 3.1e-07 30.2 7.5 3.1e-07 30.2 7.5 4.8 5 1 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OAP57640.1 - 1.2e-06 28.2 5.2 1.2e-06 28.2 5.2 5.1 6 1 2 8 8 7 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAP57640.1 - 1.7e-05 25.0 8.0 1.7e-05 25.0 8.0 4.5 4 1 1 5 5 4 1 Ring finger domain zf-RING_UBOX PF13445.6 OAP57640.1 - 2.6e-05 24.2 6.6 2.6e-05 24.2 6.6 3.0 3 0 0 3 3 3 1 RING-type zinc-finger zf-RING_5 PF14634.6 OAP57640.1 - 0.00044 20.1 7.0 0.00044 20.1 7.0 4.4 6 1 0 6 6 5 1 zinc-RING finger domain zf-RING_6 PF14835.6 OAP57640.1 - 0.00046 20.0 1.2 0.00046 20.0 1.2 3.0 3 1 0 3 3 1 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.6 OAP57640.1 - 0.0011 19.0 7.2 0.0011 19.0 7.2 3.8 4 1 0 4 4 4 1 zinc finger of C3HC4-type, RING SH3_9 PF14604.6 OAP57640.1 - 0.0023 17.7 0.1 0.0023 17.7 0.1 2.3 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 OAP57640.1 - 0.013 15.1 0.1 0.027 14.1 0.1 1.5 1 0 0 1 1 1 0 SH3 domain SH3_2 PF07653.17 OAP57640.1 - 0.044 13.5 0.4 0.11 12.1 0.0 1.9 2 0 0 2 2 2 0 Variant SH3 domain Lin-8 PF03353.15 OAP57640.1 - 4.5 6.7 16.6 0.57 9.7 5.4 2.2 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist Zn_clus PF00172.18 OAP57641.1 - 1.8e-07 31.1 9.4 3.1e-07 30.4 9.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 OAP57642.1 - 1.1e-37 129.8 52.9 1.1e-37 129.8 52.9 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 OAP57642.1 - 2.1e-14 52.9 13.5 2.1e-14 52.9 13.5 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 OAP57642.1 - 5.6e-11 42.0 11.4 5.6e-11 42.0 11.4 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter Tim17 PF02466.19 OAP57642.1 - 0.0078 16.6 0.5 0.26 11.7 0.0 3.3 2 1 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family Fungal_trans PF04082.18 OAP57643.1 - 3.9e-23 81.8 0.0 7.1e-23 81.0 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP57643.1 - 8.6e-08 32.2 12.9 1.9e-07 31.1 12.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CMD PF02627.20 OAP57644.1 - 9.5e-21 73.7 0.0 1.7e-20 72.8 0.0 1.4 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family Lactamase_B PF00753.27 OAP57645.1 - 2.2e-05 24.6 7.7 4.1e-05 23.7 7.7 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OAP57645.1 - 8.1e-05 22.2 1.1 0.00018 21.1 0.8 1.9 1 1 1 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 OAP57645.1 - 0.038 13.9 0.1 0.06 13.2 0.1 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain NAD_binding_2 PF03446.15 OAP57646.1 - 3.8e-34 118.2 0.0 4.9e-34 117.8 0.0 1.1 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 OAP57646.1 - 4.3e-16 59.3 0.0 6.9e-16 58.6 0.0 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 OAP57646.1 - 0.019 15.5 0.0 0.049 14.2 0.0 1.7 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Ldh_2 PF02615.14 OAP57647.1 - 4e-88 295.8 1.4 4.5e-88 295.6 1.4 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase MFS_1 PF07690.16 OAP57648.1 - 1.6e-30 106.2 28.3 1.6e-30 106.2 28.3 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily FAD_binding_2 PF00890.24 OAP57649.1 - 1.4e-37 129.8 0.1 1.1e-36 126.9 0.1 1.9 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 OAP57649.1 - 9e-08 31.9 0.1 1.4e-07 31.2 0.1 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 OAP57649.1 - 1.1e-06 28.5 0.1 1.1e-06 28.5 0.1 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 OAP57649.1 - 5.3e-06 25.4 0.8 0.0055 15.5 0.0 3.1 3 0 0 3 3 3 2 HI0933-like protein Pyr_redox_2 PF07992.14 OAP57649.1 - 9.7e-06 25.0 0.3 0.00024 20.4 0.2 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OAP57649.1 - 0.00021 20.5 2.0 0.00045 19.4 0.2 2.3 3 0 0 3 3 3 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 OAP57649.1 - 0.0044 17.2 0.2 0.026 14.7 0.1 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 OAP57649.1 - 0.011 15.0 0.0 0.38 10.0 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 OAP57649.1 - 0.03 13.6 0.0 0.055 12.7 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 OAP57649.1 - 0.15 11.1 0.0 0.51 9.3 0.1 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 OAP57649.1 - 0.18 11.1 0.0 0.32 10.3 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Aldedh PF00171.22 OAP57650.1 - 9.4e-147 489.2 0.0 1.1e-146 489.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Halo_GVPC PF05465.13 OAP57650.1 - 0.065 13.5 1.7 0.17 12.1 1.7 1.7 1 0 0 1 1 1 0 Halobacterial gas vesicle protein C (GVPC) repeat DUF1487 PF07368.11 OAP57650.1 - 0.26 10.7 0.0 1.1 8.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) ADH_N PF08240.12 OAP57651.1 - 4e-27 94.3 1.8 7.2e-27 93.4 1.8 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAP57651.1 - 2.3e-16 60.0 0.0 3.8e-16 59.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 OAP57651.1 - 5.2e-05 23.1 0.0 0.00026 20.8 0.0 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-associated Methyltransf_31 PF13847.6 OAP57651.1 - 0.053 13.3 0.0 0.092 12.5 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain AlaDh_PNT_C PF01262.21 OAP57651.1 - 0.099 11.9 0.0 0.29 10.4 0.0 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Methyltransf_25 PF13649.6 OAP57651.1 - 0.13 12.9 0.0 0.36 11.6 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Abhydrolase_6 PF12697.7 OAP57652.1 - 3.8e-08 34.2 0.2 5.3e-08 33.7 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Nitroreductase PF00881.24 OAP57653.1 - 2e-17 63.8 0.0 2.4e-17 63.5 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family MFS_1 PF07690.16 OAP57655.1 - 1.9e-36 125.8 29.3 1.9e-36 125.8 29.3 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 OAP57655.1 - 4.1e-06 26.3 5.6 4.1e-06 26.3 5.6 2.0 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB DUF1230 PF06799.11 OAP57655.1 - 1.3 9.1 7.3 0.082 13.0 0.6 2.4 3 0 0 3 3 3 0 Conserved in the green lineage and diatoms 27 EXS PF03124.14 OAP57655.1 - 8.2 5.6 13.8 0.14 11.4 3.2 2.7 2 1 1 3 3 3 0 EXS family Peptidase_M20 PF01546.28 OAP57656.1 - 6.4e-31 107.7 0.3 1.7e-30 106.3 0.2 1.7 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 OAP57656.1 - 0.075 12.9 0.0 0.19 11.7 0.0 1.7 1 0 0 1 1 1 0 Peptidase dimerisation domain Peptidase_M28 PF04389.17 OAP57656.1 - 0.15 11.7 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M28 E1-E2_ATPase PF00122.20 OAP57657.1 - 2.9e-46 157.2 3.9 2.9e-46 157.2 3.9 3.2 4 1 1 5 5 5 1 E1-E2 ATPase Hydrolase PF00702.26 OAP57657.1 - 7.4e-23 81.9 1.5 1.3e-22 81.1 1.5 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 OAP57657.1 - 0.011 16.1 0.0 0.04 14.4 0.0 2.1 1 0 0 1 1 1 0 Heavy-metal-associated domain HAD PF12710.7 OAP57657.1 - 0.08 13.3 0.1 0.24 11.8 0.1 1.8 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase MFS_1 PF07690.16 OAP57658.1 - 1.5e-39 136.0 71.7 1.8e-32 112.7 43.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily adh_short_C2 PF13561.6 OAP57659.1 - 3.4e-06 26.8 0.0 9.2e-06 25.4 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP57659.1 - 5e-06 26.1 0.0 2.3e-05 23.9 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase Fungal_trans_2 PF11951.8 OAP57660.1 - 1e-44 152.9 0.4 1.3e-44 152.5 0.4 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP57660.1 - 0.00023 21.2 10.5 0.00023 21.2 10.5 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dynamin_N PF00350.23 OAP57661.1 - 4.2e-28 98.5 0.0 8.2e-28 97.6 0.0 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 OAP57661.1 - 0.00041 19.6 0.0 0.0028 16.9 0.0 2.0 2 0 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.23 OAP57661.1 - 0.0011 19.0 0.0 0.0036 17.4 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase GED PF02212.18 OAP57661.1 - 0.0015 18.6 0.0 0.0041 17.2 0.0 1.7 1 0 0 1 1 1 1 Dynamin GTPase effector domain Nucleoporin_FG PF13634.6 OAP57661.1 - 0.036 14.9 33.9 0.53 11.2 19.9 3.4 2 1 0 2 2 2 0 Nucleoporin FG repeat region FtsK_SpoIIIE PF01580.18 OAP57661.1 - 0.074 12.4 0.0 0.59 9.4 0.0 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_28 PF13521.6 OAP57661.1 - 0.15 12.3 0.2 0.51 10.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain Fungal_trans PF04082.18 OAP57662.1 - 1.8e-18 66.6 0.0 3e-18 65.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aldo_ket_red PF00248.21 OAP57663.1 - 1e-47 162.8 0.0 1.3e-47 162.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Sugar_tr PF00083.24 OAP57664.1 - 2.6e-74 250.7 17.2 3.1e-74 250.5 17.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP57664.1 - 7e-17 61.4 23.9 1.1e-09 37.7 16.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hyd_65N_2 PF14498.6 OAP57665.1 - 2.1e-53 181.6 0.0 3e-53 181.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain OprD PF03573.13 OAP57665.1 - 0.089 11.8 0.0 24 3.8 0.0 2.9 3 0 0 3 3 3 0 outer membrane porin, OprD family Fungal_trans PF04082.18 OAP57666.1 - 4.8e-15 55.3 1.2 7.6e-15 54.7 1.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 OAP57666.1 - 6.9e-09 35.7 7.2 0.00016 21.9 1.5 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAP57666.1 - 0.00013 22.5 6.9 0.26 12.2 0.4 3.2 2 0 0 2 2 2 2 C2H2-type zinc finger DZR PF12773.7 OAP57666.1 - 0.032 14.2 0.5 0.086 12.9 0.5 1.7 1 0 0 1 1 1 0 Double zinc ribbon zf-C2H2_11 PF16622.5 OAP57666.1 - 0.2 11.4 9.2 0.64 9.8 1.1 2.6 2 0 0 2 2 2 0 zinc-finger C2H2-type adh_short PF00106.25 OAP57667.1 - 3.7e-43 147.3 0.0 4.9e-43 146.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP57667.1 - 4.3e-34 118.1 0.0 5.5e-34 117.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP57667.1 - 4.7e-06 26.6 0.1 1.5e-05 25.0 0.1 1.7 1 1 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 OAP57667.1 - 0.014 14.7 0.1 0.031 13.6 0.0 1.6 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Oxidored_nitro PF00148.19 OAP57667.1 - 0.036 12.8 0.1 1.3 7.7 0.0 2.1 2 0 0 2 2 2 0 Nitrogenase component 1 type Oxidoreductase Epimerase PF01370.21 OAP57667.1 - 0.042 13.3 0.0 0.43 10.0 0.0 2.0 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family ECH_1 PF00378.20 OAP57668.1 - 5.8e-53 179.8 0.0 8.6e-53 179.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAP57668.1 - 7.8e-30 104.5 0.0 1.6e-25 90.4 0.0 2.1 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 OAP57668.1 - 0.049 13.6 0.0 0.38 10.7 0.0 2.1 1 1 1 2 2 2 0 Peptidase family S49 DUF3005 PF11448.8 OAP57668.1 - 0.063 13.3 0.1 1.7 8.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3005) AMP-binding PF00501.28 OAP57669.1 - 5.9e-45 153.6 0.0 8.7e-45 153.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 OAP57669.1 - 8.3e-08 32.0 0.1 2.5e-07 30.5 0.0 1.9 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus 4HBT PF03061.22 OAP57670.1 - 6.3e-10 39.3 0.0 9.4e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_2 PF13279.6 OAP57670.1 - 1.8e-06 28.5 0.0 2.1e-06 28.2 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.17 OAP57670.1 - 0.0053 16.1 0.9 0.0082 15.5 0.8 1.3 1 1 0 1 1 1 1 Acyl-ACP thioesterase Pyr_redox_2 PF07992.14 OAP57671.1 - 5.1e-16 58.8 0.0 6.2e-14 51.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAP57671.1 - 2.7e-15 56.4 0.1 2.1e-12 46.9 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.19 OAP57671.1 - 9.8e-14 50.7 0.5 2.7e-11 42.6 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OAP57671.1 - 1.2e-11 44.4 0.1 5.7e-10 38.9 0.0 2.7 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAP57671.1 - 3.3e-11 43.2 0.0 1.1e-08 35.2 0.0 2.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAP57671.1 - 1.8e-08 34.4 0.5 1.3e-05 25.0 0.0 3.5 2 1 1 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 OAP57671.1 - 2e-06 28.3 0.3 0.015 15.8 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAP57671.1 - 5.2e-06 26.5 0.2 0.0019 18.2 0.0 3.7 3 1 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_7 PF13241.6 OAP57671.1 - 0.00046 20.6 0.0 0.24 11.9 0.0 2.7 2 0 0 2 2 2 1 Putative NAD(P)-binding Thi4 PF01946.17 OAP57671.1 - 0.00069 18.9 0.2 0.0056 15.9 0.0 2.2 3 0 0 3 3 3 1 Thi4 family Shikimate_DH PF01488.20 OAP57671.1 - 0.001 19.1 0.0 0.09 12.8 0.0 2.5 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.14 OAP57671.1 - 0.0011 17.7 0.0 0.059 12.1 0.0 2.5 3 0 0 3 3 3 1 HI0933-like protein FAD_binding_2 PF00890.24 OAP57671.1 - 0.0041 16.3 0.0 0.0092 15.1 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain 2-Hacid_dh_C PF02826.19 OAP57671.1 - 0.011 15.1 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 OAP57671.1 - 0.011 14.8 0.0 2.2 7.2 0.0 3.0 3 0 0 3 3 3 0 Lycopene cyclase protein NAD_binding_2 PF03446.15 OAP57671.1 - 0.061 13.5 0.1 0.65 10.1 0.0 2.1 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase GIDA PF01134.22 OAP57671.1 - 0.091 11.8 0.1 16 4.5 0.0 2.7 3 0 0 3 3 3 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 OAP57671.1 - 0.73 9.1 4.1 23 4.2 1.0 3.0 2 1 1 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain adh_short_C2 PF13561.6 OAP57672.1 - 1.3e-60 204.9 0.1 1.6e-60 204.6 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP57672.1 - 2e-45 154.7 0.3 2.6e-45 154.3 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAP57672.1 - 4.5e-07 29.9 1.0 9.9e-07 28.8 1.0 1.7 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OAP57672.1 - 0.0043 16.2 0.1 0.0064 15.7 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Arylesterase PF01731.20 OAP57673.1 - 4.6e-07 29.9 0.0 1.1e-06 28.8 0.0 1.6 1 0 0 1 1 1 1 Arylesterase SGL PF08450.12 OAP57673.1 - 0.00019 21.1 0.0 0.00034 20.3 0.0 1.4 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 OAP57673.1 - 0.029 14.5 0.1 0.11 12.6 0.0 2.0 2 0 0 2 2 2 0 Strictosidine synthase ABM PF03992.16 OAP57674.1 - 2e-11 43.8 0.1 2.3e-11 43.6 0.1 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase TPR_14 PF13428.6 OAP57674.1 - 0.042 14.7 1.5 0.053 14.4 0.5 1.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Sugar_tr PF00083.24 OAP57675.1 - 3.2e-87 293.3 19.4 3.7e-87 293.1 19.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP57675.1 - 7.6e-20 71.1 32.1 1.4e-17 63.7 19.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DIOX_N PF14226.6 OAP57676.1 - 9.3e-17 61.9 0.6 2.9e-16 60.3 0.0 2.0 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OAP57676.1 - 3e-11 43.7 0.0 8.8e-11 42.2 0.0 1.9 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Ppx-GppA PF02541.16 OAP57677.1 - 3.4e-43 148.1 0.0 8.9e-43 146.7 0.0 1.6 1 1 0 1 1 1 1 Ppx/GppA phosphatase family DIOX_N PF14226.6 OAP57678.1 - 1.8e-30 106.1 0.0 2.9e-30 105.4 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OAP57678.1 - 1.5e-18 67.1 0.0 2.7e-18 66.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Transp_cyt_pur PF02133.15 OAP57679.1 - 3e-91 306.4 39.4 3.4e-91 306.2 39.4 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin TIR_2 PF13676.6 OAP57680.1 - 0.012 16.3 0.0 0.061 13.9 0.0 2.2 1 0 0 1 1 1 0 TIR domain DUF1127 PF06568.11 OAP57680.1 - 0.63 9.8 3.6 15 5.4 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1127) LSM14 PF12701.7 OAP57681.1 - 5.9e-27 93.6 0.1 9.4e-27 92.9 0.1 1.3 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.10 OAP57681.1 - 1.5e-18 67.6 4.7 1.5e-18 67.6 4.7 1.9 2 0 0 2 2 2 1 FDF domain SM-ATX PF14438.6 OAP57681.1 - 0.0021 18.2 0.0 0.0044 17.1 0.0 1.5 1 0 0 1 1 1 1 Ataxin 2 SM domain GRP PF07172.11 OAP57681.1 - 1.5 9.6 33.2 1.5 9.6 0.9 2.5 2 0 0 2 2 2 0 Glycine rich protein family WD40 PF00400.32 OAP57682.1 - 1e-12 48.3 12.3 0.0073 17.1 0.1 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.8 OAP57682.1 - 0.0042 15.8 2.2 0.36 9.4 0.5 3.4 3 1 0 4 4 4 2 Nucleoporin Nup120/160 Thioredox_DsbH PF03190.15 OAP57683.1 - 1.6e-65 220.0 0.0 2.8e-65 219.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.6 OAP57683.1 - 2.5e-07 30.8 0.0 5.8e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like GlcNAc_2-epim PF07221.11 OAP57683.1 - 0.0074 15.6 0.2 1.2 8.3 0.0 2.5 1 1 1 2 2 2 2 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) Epimerase PF01370.21 OAP57684.1 - 7.7e-09 35.4 0.0 4.2e-08 32.9 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.17 OAP57684.1 - 0.056 14.0 0.1 0.28 11.8 0.0 2.0 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent NmrA PF05368.13 OAP57684.1 - 0.078 12.5 0.0 0.15 11.6 0.0 1.6 1 1 0 1 1 1 0 NmrA-like family NAD_binding_4 PF07993.12 OAP57684.1 - 0.085 12.0 0.0 0.16 11.1 0.0 1.5 1 0 0 1 1 1 0 Male sterility protein PDDEXK_10 PF07788.11 OAP57684.1 - 0.12 12.4 0.0 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 PD-(D/E)XK nuclease superfamily 3Beta_HSD PF01073.19 OAP57684.1 - 0.13 11.2 0.0 0.4 9.6 0.0 1.8 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family PBP_sp32 PF07222.12 OAP57685.1 - 9.8 5.6 16.3 1.5 8.2 12.0 1.8 2 0 0 2 2 2 0 Proacrosin binding protein sp32 T3SS_needle_reg PF09025.10 OAP57686.1 - 0.071 13.1 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 YopR, type III needle-polymerisation regulator GST_N_2 PF13409.6 OAP57687.1 - 6.3e-10 39.2 0.0 1.3e-09 38.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 OAP57687.1 - 2.7e-08 33.9 0.0 1e-07 32.1 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 OAP57687.1 - 1.9e-07 31.4 0.0 3.1e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 OAP57687.1 - 1.9e-07 31.3 0.0 3.3e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OAP57687.1 - 5.9e-06 26.4 0.0 1.2e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OAP57687.1 - 0.0057 16.7 0.0 0.0085 16.1 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Phosphonate-bd PF12974.7 OAP57688.1 - 0.2 11.2 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein Fungal_trans PF04082.18 OAP57689.1 - 4.9e-20 71.7 3.5 1.9e-19 69.7 1.0 2.5 2 1 0 2 2 2 1 Fungal specific transcription factor domain SOBP PF15279.6 OAP57690.1 - 0.19 12.3 0.2 0.19 12.3 0.2 2.4 3 0 0 3 3 3 0 Sine oculis-binding protein NDK PF00334.19 OAP57691.1 - 6.5e-54 181.6 0.0 7.4e-54 181.4 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Glyco_hydro_31 PF01055.26 OAP57692.1 - 4.9e-141 470.9 6.8 6.5e-141 470.5 6.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 OAP57692.1 - 1.1e-27 96.1 1.0 4.5e-26 91.0 0.4 2.7 2 0 0 2 2 2 1 Galactose mutarotase-like DUF5110 PF17137.4 OAP57692.1 - 7.7e-07 29.3 0.3 4.7e-06 26.8 0.2 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF5110) Gp5_C PF06715.12 OAP57692.1 - 0.051 13.7 0.1 0.32 11.2 0.1 2.4 1 0 0 1 1 1 0 Gp5 C-terminal repeat (3 copies) Pih1_fungal_CS PF18482.1 OAP57692.1 - 0.2 12.2 0.0 0.45 11.1 0.0 1.5 1 0 0 1 1 1 0 Fungal Pih1 CS domain DUF347 PF03988.12 OAP57693.1 - 0.0009 19.4 1.2 0.0021 18.2 0.5 1.9 2 0 0 2 2 2 1 Repeat of Unknown Function (DUF347) Alpha_GJ PF03229.13 OAP57693.1 - 0.0051 17.4 3.3 0.016 15.7 3.3 1.9 1 0 0 1 1 1 1 Alphavirus glycoprotein J MGC-24 PF05283.11 OAP57693.1 - 0.21 12.0 5.7 0.031 14.7 1.9 1.6 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Smg8_Smg9 PF10220.9 OAP57693.1 - 0.29 9.4 0.4 0.39 9.0 0.4 1.1 1 0 0 1 1 1 0 Smg8_Smg9 PQ-loop PF04193.14 OAP57694.1 - 7e-24 83.4 6.7 1.3e-15 56.9 0.1 3.0 3 0 0 3 3 3 2 PQ loop repeat ER_lumen_recept PF00810.18 OAP57694.1 - 0.052 14.4 3.3 0.21 12.4 3.3 1.9 1 1 0 1 1 1 0 ER lumen protein retaining receptor Phage_holin_5_2 PF16079.5 OAP57694.1 - 0.085 13.2 1.4 2.9 8.3 0.1 2.4 2 0 0 2 2 2 0 Phage holin family Hol44, in holin superfamily V AzlD PF05437.12 OAP57694.1 - 0.75 10.0 5.2 0.28 11.4 0.4 2.2 2 0 0 2 2 2 0 Branched-chain amino acid transport protein (AzlD) SOG2 PF10428.9 OAP57695.1 - 2.9 7.0 13.5 4.1 6.5 13.5 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein MFS_1 PF07690.16 OAP57697.1 - 3.6e-36 124.8 33.6 3.6e-36 124.8 33.6 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 OAP57697.1 - 1.5e-09 36.9 6.3 2.2e-09 36.3 6.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) LapA_dom PF06305.11 OAP57697.1 - 1.3 8.9 0.0 1.3 8.9 0.0 3.9 4 0 0 4 4 4 0 Lipopolysaccharide assembly protein A domain DUF2237 PF09996.9 OAP57698.1 - 2.6e-39 133.8 0.1 3.3e-39 133.4 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2237) ACBP PF00887.19 OAP57699.1 - 4e-22 78.2 0.0 1.2e-21 76.7 0.0 1.8 2 0 0 2 2 2 1 Acyl CoA binding protein FERM_M PF00373.18 OAP57699.1 - 0.026 14.9 0.0 0.053 13.9 0.0 1.5 1 0 0 1 1 1 0 FERM central domain MFS_1 PF07690.16 OAP57700.1 - 5e-39 134.2 25.2 5e-39 134.2 25.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.18 OAP57701.1 - 2.1e-25 89.3 1.0 2.5e-25 89.0 0.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP57701.1 - 8.1e-09 35.5 7.8 1.4e-08 34.7 7.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.25 OAP57702.1 - 5.6e-53 180.0 0.0 7.3e-53 179.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP57702.1 - 1.7e-27 96.3 0.0 2.8e-27 95.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAP57702.1 - 1.4e-05 24.6 0.0 2.3e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OAP57702.1 - 0.017 14.5 0.0 0.036 13.4 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ank_2 PF12796.7 OAP57703.1 - 2.4e-51 172.2 8.1 5.7e-13 49.3 0.4 5.9 2 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAP57703.1 - 2.4e-39 133.2 3.8 1.4e-06 28.7 0.0 8.6 4 2 4 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAP57703.1 - 6.4e-36 118.3 4.4 0.00058 20.1 0.0 11.5 11 0 0 11 11 11 8 Ankyrin repeat Ank PF00023.30 OAP57703.1 - 1.3e-35 120.3 17.0 2.4e-05 24.6 0.1 11.5 10 1 1 11 11 11 10 Ankyrin repeat Ank_5 PF13857.6 OAP57703.1 - 3.9e-34 116.3 6.2 0.00019 21.6 0.0 7.7 4 1 3 7 7 7 7 Ankyrin repeats (many copies) AAA_22 PF13401.6 OAP57703.1 - 0.0081 16.4 0.0 0.032 14.5 0.0 2.0 1 0 0 1 1 1 1 AAA domain Pkinase_Tyr PF07714.17 OAP57704.1 - 0.0037 16.6 0.0 0.12 11.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 OAP57704.1 - 0.0051 16.2 0.0 1.6 8.0 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain ADH_zinc_N PF00107.26 OAP57705.1 - 5.9e-15 55.4 0.0 1.1e-14 54.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAP57705.1 - 1.1e-12 49.2 0.0 2.7e-12 47.9 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAP57705.1 - 6.8e-09 35.6 0.0 3.4e-08 33.3 0.0 2.2 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ResIII PF04851.15 OAP57706.1 - 2.9e-21 76.2 0.0 6.3e-21 75.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 OAP57706.1 - 8.6e-21 74.4 0.1 4.2e-20 72.2 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 OAP57706.1 - 6.2e-18 65.2 0.0 1.8e-17 63.7 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 OAP57706.1 - 0.1 12.9 0.0 0.33 11.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 OAP57706.1 - 0.18 11.7 0.0 0.45 10.4 0.0 1.6 1 0 0 1 1 1 0 NACHT domain HUN PF08729.10 OAP57706.1 - 0.18 11.8 6.2 0.047 13.7 2.0 2.2 2 0 0 2 2 2 0 HPC2 and ubinuclein domain Metallophos PF00149.28 OAP57708.1 - 1.1e-10 42.4 0.0 1.9e-10 41.6 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OAP57708.1 - 1.7e-06 28.4 0.9 1e-05 25.8 0.9 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain FBPase_2 PF06874.11 OAP57708.1 - 0.033 12.5 0.1 0.099 10.9 0.1 1.5 1 1 1 2 2 2 0 Firmicute fructose-1,6-bisphosphatase Ins_allergen_rp PF06757.13 OAP57708.1 - 0.1 12.6 0.0 0.28 11.1 0.0 1.7 2 0 0 2 2 2 0 Insect allergen related repeat, nitrile-specifier detoxification DUF4286 PF14114.6 OAP57709.1 - 1 9.9 6.2 12 6.5 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4286) HALZ PF02183.18 OAP57709.1 - 1.7 8.9 8.2 0.84 9.9 0.7 2.8 2 0 0 2 2 2 0 Homeobox associated leucine zipper Mit_KHE1 PF10173.9 OAP57709.1 - 2.2 8.3 5.7 0.6 10.2 1.6 2.1 2 0 0 2 2 2 0 Mitochondrial K+-H+ exchange-related Pcc1 PF09341.10 OAP57709.1 - 4.2 7.6 10.0 0.091 12.9 1.2 2.7 3 0 0 3 3 3 0 Transcription factor Pcc1 AbiEii PF08843.11 OAP57711.1 - 0.0012 18.8 0.0 0.0037 17.2 0.0 1.8 1 1 0 1 1 1 1 Nucleotidyl transferase AbiEii toxin, Type IV TA system Metallophos PF00149.28 OAP57712.1 - 8.2e-08 33.0 5.6 0.00087 19.8 0.4 2.7 3 0 0 3 3 3 2 Calcineurin-like phosphoesterase Suc_Fer-like PF06999.12 OAP57713.1 - 5.6e-54 183.0 0.0 7.1e-54 182.6 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Ring_hydroxyl_A PF00848.19 OAP57714.1 - 1e-26 94.2 0.9 8.9e-24 84.6 0.9 2.4 1 1 0 1 1 1 1 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.26 OAP57714.1 - 5e-16 58.4 0.0 9.3e-16 57.6 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain XRN1_DBM PF18245.1 OAP57714.1 - 0.076 13.0 0.0 0.26 11.3 0.0 1.9 1 0 0 1 1 1 0 5-3 exonuclease XRN1 DCP1-binding motif Fungal_trans_2 PF11951.8 OAP57715.1 - 8.7e-39 133.4 2.1 1.3e-38 132.9 2.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP57715.1 - 0.039 14.1 0.6 0.039 14.1 0.6 1.8 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldolase_II PF00596.21 OAP57716.1 - 5.7e-28 98.1 0.0 7.5e-28 97.7 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Hormone_3 PF00159.18 OAP57716.1 - 0.26 11.4 1.6 0.59 10.3 0.1 2.3 2 0 0 2 2 2 0 Pancreatic hormone peptide Sugar_tr PF00083.24 OAP57717.1 - 3.2e-128 428.4 28.5 3.7e-128 428.2 28.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP57717.1 - 2.2e-24 86.0 47.2 7.7e-19 67.8 22.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily IBR PF01485.21 OAP57718.1 - 2.1e-19 69.5 38.1 3.1e-15 56.1 3.7 3.7 3 1 1 4 4 4 3 IBR domain, a half RING-finger domain RWD PF05773.22 OAP57718.1 - 1.3e-17 64.1 0.1 3.3e-17 62.8 0.1 1.7 1 0 0 1 1 1 1 RWD domain zf-RING_2 PF13639.6 OAP57718.1 - 0.0048 17.2 10.5 0.0048 17.2 10.5 4.2 3 1 1 4 4 4 2 Ring finger domain zf-RING_UBOX PF13445.6 OAP57718.1 - 0.014 15.4 9.7 0.014 15.4 9.7 3.8 3 0 0 3 3 3 0 RING-type zinc-finger PAP2 PF01569.21 OAP57719.1 - 1.1e-12 47.8 4.7 1.1e-12 47.8 4.7 1.9 1 1 0 1 1 1 1 PAP2 superfamily DUF212 PF02681.14 OAP57719.1 - 0.00093 19.3 0.1 0.053 13.7 0.0 2.3 2 0 0 2 2 2 1 Divergent PAP2 family DUF202 PF02656.15 OAP57719.1 - 2.6 8.6 6.7 4.5 7.8 4.0 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF202) DUF3934 PF13070.6 OAP57719.1 - 6.2 7.4 9.1 2 9.0 5.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3934) CPBP PF02517.16 OAP57720.1 - 4.3e-14 52.7 12.9 4.3e-14 52.7 12.9 2.2 2 1 0 2 2 2 1 CPBP intramembrane metalloprotease Synaptobrevin PF00957.21 OAP57721.1 - 0.36 10.6 0.8 0.73 9.7 0.8 1.4 1 0 0 1 1 1 0 Synaptobrevin HET PF06985.11 OAP57722.1 - 0.013 15.8 0.3 1.5 9.2 0.0 2.7 1 1 1 2 2 2 0 Heterokaryon incompatibility protein (HET) ER_lumen_recept PF00810.18 OAP57724.1 - 1.7e-54 184.6 7.3 2.5e-54 184.1 7.3 1.2 1 0 0 1 1 1 1 ER lumen protein retaining receptor DUF485 PF04341.12 OAP57724.1 - 0.0016 18.4 5.3 0.012 15.5 0.1 2.8 2 1 1 3 3 3 2 Protein of unknown function, DUF485 PQ-loop PF04193.14 OAP57724.1 - 0.062 13.1 9.9 2.9 7.7 0.1 4.0 4 0 0 4 4 4 0 PQ loop repeat Integrase_H2C2 PF17921.1 OAP57726.1 - 4.3e-08 33.1 2.2 5.3e-08 32.8 0.6 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain Tcell_CD4_C PF12104.8 OAP57726.1 - 0.95 9.4 0.0 0.95 9.4 0.0 2.7 3 0 0 3 3 3 0 T cell CD4 receptor C terminal region QRPTase_C PF01729.19 OAP57727.1 - 4.9e-54 182.6 0.2 6.1e-54 182.3 0.2 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 OAP57727.1 - 7.5e-19 67.6 0.0 2.9e-18 65.7 0.0 2.0 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain IGPS PF00218.21 OAP57727.1 - 0.014 14.6 0.2 0.025 13.7 0.1 1.4 2 0 0 2 2 2 0 Indole-3-glycerol phosphate synthase WD40 PF00400.32 OAP57729.1 - 2.7e-10 40.7 7.9 0.043 14.7 0.0 6.7 7 0 0 7 7 7 4 WD domain, G-beta repeat Myb_DNA-bind_4 PF13837.6 OAP57729.1 - 4e-05 23.9 0.6 8.1e-05 22.9 0.6 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain eIF2A PF08662.11 OAP57729.1 - 0.017 15.0 0.0 14 5.5 0.0 3.0 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 OAP57729.1 - 0.017 15.4 0.0 8.1 6.8 0.0 3.9 5 0 0 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain CCDC53 PF10152.9 OAP57729.1 - 3.6 8.0 16.1 3.5 8.0 4.9 3.2 3 0 0 3 3 3 0 Subunit CCDC53 of WASH complex DUF5572 PF17733.1 OAP57730.1 - 5.1e-18 64.6 2.1 1.1e-17 63.6 2.1 1.6 1 0 0 1 1 1 1 Family of unknown function (DUF5572) Ndc1_Nup PF09531.10 OAP57730.1 - 0.22 10.2 1.6 0.25 10.0 1.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PUF PF00806.19 OAP57731.1 - 4.1e-38 126.9 4.2 1.3e-05 24.6 0.0 8.9 9 0 0 9 9 9 7 Pumilio-family RNA binding repeat RraB PF06877.11 OAP57731.1 - 0.0018 18.9 0.1 0.73 10.6 0.0 2.8 2 1 1 3 3 3 1 Regulator of ribonuclease activity B AIP3 PF03915.13 OAP57731.1 - 0.0097 15.0 3.3 0.014 14.5 3.3 1.1 1 0 0 1 1 1 1 Actin interacting protein 3 Spc7 PF08317.11 OAP57731.1 - 0.089 11.7 7.5 0.14 11.0 7.5 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4618 PF15397.6 OAP57731.1 - 0.89 8.9 10.6 1.5 8.2 10.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) DUF4200 PF13863.6 OAP57731.1 - 3 8.3 8.3 5.3 7.5 8.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Spc24 PF08286.11 OAP57731.1 - 4.9 7.5 5.8 13 6.1 5.8 1.7 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 Peptidase_S9 PF00326.21 OAP57732.1 - 7.8e-09 35.3 0.5 1.3e-08 34.5 0.5 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 OAP57732.1 - 0.0059 16.4 0.0 0.87 9.4 0.0 2.5 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Esterase PF00756.20 OAP57732.1 - 0.014 15.1 0.7 0.028 14.1 0.7 1.5 1 0 0 1 1 1 0 Putative esterase Hydrolase_4 PF12146.8 OAP57732.1 - 0.093 12.0 0.0 0.51 9.6 0.0 2.1 2 1 1 3 3 3 0 Serine aminopeptidase, S33 TPT PF03151.16 OAP57733.1 - 1.1e-59 202.2 12.8 1.4e-59 201.9 12.8 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 OAP57733.1 - 1.1e-05 25.6 32.9 0.00071 19.8 9.8 3.2 2 1 0 2 2 2 2 EamA-like transporter family TMEM100 PF16311.5 OAP57733.1 - 0.023 14.3 2.2 0.098 12.3 0.1 2.3 2 0 0 2 2 2 0 Transmembrane protein 100 UAA PF08449.11 OAP57733.1 - 0.024 13.8 15.8 0.65 9.1 15.8 2.3 1 1 0 1 1 1 0 UAA transporter family YjcB PF15940.5 OAP57733.1 - 0.2 11.8 3.9 0.43 10.8 0.2 2.6 2 0 0 2 2 2 0 Family of unknown function 2TM PF13239.6 OAP57733.1 - 4.9 7.5 7.0 11 6.4 0.1 2.9 3 0 0 3 3 3 0 2TM domain CDC50 PF03381.15 OAP57734.1 - 1.7e-96 323.0 0.1 2.1e-96 322.7 0.1 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Peptidase_M43 PF05572.13 OAP57735.1 - 8.6e-10 38.7 2.3 5.4e-08 32.9 2.3 2.5 1 1 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 OAP57735.1 - 5.4e-06 26.7 9.1 1.3e-05 25.4 9.1 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 OAP57735.1 - 0.022 14.4 0.3 0.044 13.4 0.3 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 OAP57735.1 - 0.033 14.0 0.0 0.044 13.6 0.0 1.2 1 0 0 1 1 1 0 Matrixin Reprolysin_3 PF13582.6 OAP57735.1 - 0.044 14.3 0.6 0.15 12.6 0.6 1.9 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 OAP57735.1 - 0.31 10.9 4.9 0.46 10.4 4.9 1.4 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Methyltransf_25 PF13649.6 OAP57736.1 - 5.2e-15 55.9 0.0 4.6e-13 49.7 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAP57736.1 - 1.1e-13 51.3 0.0 2.6e-13 50.0 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAP57736.1 - 2.2e-12 47.4 0.0 3e-08 34.2 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 OAP57736.1 - 8.2e-11 42.5 0.0 1.5e-10 41.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAP57736.1 - 3.8e-09 36.6 0.0 5.6e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 OAP57736.1 - 6.8e-05 22.9 0.0 9.4e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OAP57736.1 - 0.00056 19.5 0.0 0.015 14.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase small domain PCMT PF01135.19 OAP57736.1 - 0.00075 19.3 0.0 0.0014 18.4 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.18 OAP57736.1 - 0.00098 18.5 0.0 0.0019 17.6 0.0 1.4 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 OAP57736.1 - 0.0043 17.2 0.0 0.012 15.8 0.0 1.7 1 1 0 1 1 1 1 FtsJ-like methyltransferase Pox_MCEL PF03291.16 OAP57736.1 - 0.0047 16.1 0.0 0.014 14.6 0.0 1.7 1 1 0 1 1 1 1 mRNA capping enzyme NNMT_PNMT_TEMT PF01234.17 OAP57736.1 - 0.017 14.3 0.0 0.029 13.6 0.0 1.3 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family SKIP_SNW PF02731.15 OAP57737.1 - 1.6e-71 239.2 5.1 1.6e-71 239.2 5.1 2.5 3 0 0 3 3 3 1 SKIP/SNW domain LRIF1 PF15741.5 OAP57737.1 - 0.47 8.9 7.6 0.68 8.4 7.6 1.1 1 0 0 1 1 1 0 Ligand-dependent nuclear receptor-interacting factor 1 COX17 PF05051.13 OAP57738.1 - 1.5e-20 73.3 8.3 2e-20 72.9 8.3 1.2 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Sec10 PF07393.11 OAP57739.1 - 2.7e-205 683.9 0.0 3.3e-205 683.7 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 ALIX_LYPXL_bnd PF13949.6 OAP57739.1 - 0.0056 16.0 4.4 1.5 8.1 1.6 2.4 2 0 0 2 2 2 2 ALIX V-shaped domain binding to HIV Opi1 PF08618.10 OAP57740.1 - 1.4e-34 120.1 3.4 1.4e-25 90.5 0.3 2.2 1 1 1 2 2 2 2 Transcription factor Opi1 UL42 PF17638.2 OAP57740.1 - 5 7.1 6.2 6.5 6.8 4.4 2.0 2 0 0 2 2 2 0 HCMV UL42 PSDC PF12588.8 OAP57741.1 - 4e-27 94.9 0.1 1.4e-23 83.4 0.0 2.2 1 1 1 2 2 2 2 Phophatidylserine decarboxylase PS_Dcarbxylase PF02666.15 OAP57741.1 - 3e-24 85.7 0.0 6.8e-24 84.5 0.0 1.5 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase Gemini_V2 PF01524.17 OAP57741.1 - 0.08 13.1 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 Geminivirus V2 protein MFS_1 PF07690.16 OAP57742.1 - 1.1e-18 67.3 39.8 1.1e-18 67.3 39.8 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1970 PF09301.10 OAP57742.1 - 0.066 13.5 0.5 0.74 10.1 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF1970) HSCB_C PF07743.13 OAP57746.1 - 1.7e-15 57.2 7.9 7.2e-15 55.2 6.7 2.0 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 OAP57746.1 - 2.7e-05 24.2 0.2 9.5e-05 22.5 0.0 1.9 2 0 0 2 2 2 1 DnaJ domain Sin3a_C PF16879.5 OAP57748.1 - 6.5e-68 229.5 1.7 6.5e-68 229.5 1.7 3.5 4 0 0 4 4 4 1 C-terminal domain of Sin3a protein PAH PF02671.21 OAP57748.1 - 4.9e-47 157.8 2.7 6e-18 64.7 0.0 3.9 3 1 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.12 OAP57748.1 - 3.2e-39 133.0 0.0 7.5e-39 131.8 0.0 1.7 1 0 0 1 1 1 1 Sin3 family co-repressor Sporozoite_P67 PF05642.11 OAP57748.1 - 1.8 6.6 7.1 0.38 8.8 0.5 2.2 2 0 0 2 2 2 0 Sporozoite P67 surface antigen Ank_2 PF12796.7 OAP57751.1 - 1.1e-36 125.2 4.4 1.3e-11 44.9 0.3 4.9 2 1 2 5 5 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAP57751.1 - 1e-28 99.3 1.2 3.9e-09 36.9 0.1 6.1 4 2 3 7 7 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 OAP57751.1 - 2.6e-23 81.8 3.4 2.1e-09 37.5 0.1 4.8 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 OAP57751.1 - 9.6e-18 63.8 3.1 0.012 16.1 0.0 6.9 6 0 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.6 OAP57751.1 - 4.9e-17 60.3 1.0 0.3 11.8 0.0 8.2 8 0 0 8 8 8 3 Ankyrin repeat NACHT PF05729.12 OAP57751.1 - 4.5e-08 33.2 0.0 9.6e-08 32.1 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 OAP57751.1 - 5.7e-06 26.8 0.5 0.00033 21.1 0.1 3.1 3 0 0 3 3 3 1 AAA ATPase domain ATPase_2 PF01637.18 OAP57751.1 - 1.8e-05 24.8 0.0 4e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 OAP57751.1 - 0.00054 20.2 0.0 0.011 16.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain KAP_NTPase PF07693.14 OAP57751.1 - 0.015 14.5 0.2 0.097 11.9 0.1 2.2 3 0 0 3 3 3 0 KAP family P-loop domain AAA_14 PF13173.6 OAP57751.1 - 0.027 14.5 0.0 0.11 12.5 0.0 2.0 1 1 0 1 1 1 0 AAA domain Goodbye PF17109.5 OAP57751.1 - 0.03 14.8 0.0 0.11 13.0 0.0 2.0 1 0 0 1 1 1 0 fungal STAND N-terminal Goodbye domain TsaE PF02367.17 OAP57751.1 - 0.041 13.9 0.0 0.087 12.8 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NB-ARC PF00931.22 OAP57751.1 - 0.15 11.2 0.0 0.28 10.3 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA PF00004.29 OAP57751.1 - 0.15 12.5 0.0 1.7 9.1 0.0 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Sugar_tr PF00083.24 OAP57753.1 - 7e-63 213.0 18.3 8.3e-63 212.8 18.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP57753.1 - 1.4e-16 60.4 32.0 1.4e-16 60.4 32.0 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF1952 PF09189.10 OAP57753.1 - 0.048 13.5 0.0 0.24 11.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1952) Asp PF00026.23 OAP57755.1 - 4.3e-08 32.9 0.0 6.5e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease ArfA PF03889.13 OAP57755.1 - 0.19 11.3 0.4 3.2 7.3 0.0 2.5 2 0 0 2 2 2 0 Alternative ribosome-rescue factor A HAT_KAT11 PF08214.11 OAP57756.1 - 1.9e-81 274.1 0.0 2.4e-81 273.7 0.0 1.1 1 0 0 1 1 1 1 Histone acetylation protein WW PF00397.26 OAP57758.1 - 3.4e-09 36.6 1.1 7.4e-09 35.5 1.1 1.6 1 0 0 1 1 1 1 WW domain Glyco_transf_21 PF13506.6 OAP57759.1 - 3.8e-09 36.3 0.0 0.0018 17.8 0.0 3.6 4 0 0 4 4 4 3 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 OAP57759.1 - 0.03 14.2 0.1 0.16 11.8 0.0 2.3 2 1 0 2 2 2 0 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 OAP57761.1 - 8.2e-33 113.6 0.0 1e-32 113.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 OAP57761.1 - 3e-13 50.2 0.0 3.8e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 OAP57761.1 - 6.1e-05 22.6 0.0 8e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7N PF13733.6 OAP57761.1 - 0.0097 15.5 0.0 0.019 14.6 0.0 1.4 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_21 PF13506.6 OAP57761.1 - 0.17 11.4 0.0 0.32 10.5 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 21 TPR_19 PF14559.6 OAP57762.1 - 2.7e-05 24.6 0.0 0.051 14.1 0.0 2.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 OAP57762.1 - 0.011 16.3 0.1 3 8.7 0.0 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 OAP57762.1 - 0.039 14.1 0.1 0.92 9.8 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 OAP57762.1 - 0.051 13.8 0.1 39 4.8 0.1 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 OAP57762.1 - 0.053 13.4 0.3 0.15 12.0 0.1 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 OAP57762.1 - 0.15 12.4 0.1 1.3 9.4 0.1 2.4 2 1 1 3 3 3 0 Tetratricopeptide repeat HlyIII PF03006.20 OAP57763.1 - 9.7e-33 113.8 4.3 1.3e-32 113.4 4.3 1.1 1 0 0 1 1 1 1 Haemolysin-III related SAC3_GANP PF03399.16 OAP57764.1 - 0.015 14.7 0.0 0.077 12.4 0.0 1.9 2 0 0 2 2 2 0 SAC3/GANP family Vps35 PF03635.17 OAP57766.1 - 0 1022.3 0.0 0 1022.1 0.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 VTC PF09359.10 OAP57767.1 - 7.7e-86 287.9 0.6 1.4e-85 287.1 0.6 1.4 1 0 0 1 1 1 1 VTC domain DUF202 PF02656.15 OAP57767.1 - 8.7e-11 42.1 6.8 9.2e-11 42.0 5.4 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) SPX PF03105.19 OAP57767.1 - 6.4e-09 36.2 14.4 7.7e-05 22.8 0.5 3.2 2 1 1 3 3 3 2 SPX domain UXS1_N PF11803.8 OAP57767.1 - 0.055 13.8 1.4 49 4.4 0.1 3.5 3 0 0 3 3 3 0 UDP-glucuronate decarboxylase N-terminal NCE101 PF11654.8 OAP57767.1 - 0.14 11.9 0.1 0.37 10.5 0.1 1.7 1 0 0 1 1 1 0 Non-classical export protein 1 NUDIX PF00293.28 OAP57768.1 - 8.3e-12 45.3 0.0 1.5e-11 44.5 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Zn_clus PF00172.18 OAP57770.1 - 9.7e-09 35.2 10.7 2.2e-08 34.1 10.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 OAP57770.1 - 0.00011 21.2 0.0 0.00023 20.1 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain PSI_integrin PF17205.3 OAP57770.1 - 0.14 11.9 3.8 0.095 12.5 1.2 2.0 2 0 0 2 2 2 0 Integrin plexin domain Solute_trans_a PF03619.16 OAP57771.1 - 8.4e-44 150.1 13.4 1e-43 149.8 13.4 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha SHR3_chaperone PF08229.11 OAP57771.1 - 0.056 12.4 0.2 0.29 10.1 0.0 2.2 2 0 0 2 2 2 0 ER membrane protein SH3 DUF2339 PF10101.9 OAP57771.1 - 0.12 10.9 10.8 0.25 9.9 10.8 1.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2339) FixQ PF05545.11 OAP57771.1 - 0.2 11.7 0.0 0.2 11.7 0.0 3.4 3 0 0 3 3 3 0 Cbb3-type cytochrome oxidase component FixQ Protocadherin PF08374.11 OAP57771.1 - 0.33 10.9 0.8 5.1 7.0 0.5 2.2 2 0 0 2 2 2 0 Protocadherin EI24 PF07264.11 OAP57771.1 - 4.9 7.4 11.6 34 4.6 11.5 2.2 1 1 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) Yippee-Mis18 PF03226.14 OAP57773.1 - 0.26 11.5 0.0 0.34 11.1 0.0 1.1 1 0 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly ORC6 PF05460.13 OAP57774.1 - 0.22 10.8 3.3 0.28 10.4 3.3 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Myb_DNA-binding PF00249.31 OAP57777.1 - 0.0013 18.9 0.0 0.0022 18.1 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 OAP57777.1 - 0.013 15.8 0.0 0.026 14.8 0.0 1.6 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Cofilin_ADF PF00241.20 OAP57778.1 - 3.3e-34 117.3 0.0 3.8e-34 117.1 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein COX4 PF02936.14 OAP57779.1 - 3e-48 163.3 1.2 3.5e-48 163.1 1.2 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV B12D PF06522.11 OAP57779.1 - 0.0024 17.6 0.3 0.082 12.7 0.0 2.4 2 0 0 2 2 2 1 NADH-ubiquinone reductase complex 1 MLRQ subunit DUF1104 PF06518.11 OAP57779.1 - 0.095 13.1 0.3 0.2 12.1 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1104) DUF3961 PF13106.6 OAP57779.1 - 0.22 11.2 0.6 0.42 10.3 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3961) DUF3106 PF11304.8 OAP57779.1 - 0.31 11.5 7.5 0.074 13.5 4.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3106) ATP-synt_ab PF00006.25 OAP57780.1 - 2e-61 207.3 0.2 5.6e-61 205.9 0.0 1.8 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 OAP57780.1 - 8.9e-23 80.6 0.6 5e-22 78.2 0.4 2.3 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain AAA PF00004.29 OAP57780.1 - 0.0098 16.3 0.1 0.85 10.0 0.0 2.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 OAP57780.1 - 0.011 15.6 0.3 0.025 14.5 0.1 1.7 2 0 0 2 2 2 0 RsgA GTPase NB-ARC PF00931.22 OAP57780.1 - 0.012 14.9 0.3 0.082 12.1 0.1 2.1 2 0 0 2 2 2 0 NB-ARC domain ATPase_2 PF01637.18 OAP57780.1 - 0.027 14.4 0.0 0.085 12.8 0.0 1.7 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea T3SS_ATPase_C PF18269.1 OAP57780.1 - 0.032 14.1 0.8 0.14 12.0 0.8 2.0 1 1 0 1 1 1 0 T3SS EscN ATPase C-terminal domain AAA_19 PF13245.6 OAP57780.1 - 0.036 14.4 1.1 0.48 10.7 0.2 2.3 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 OAP57780.1 - 0.041 13.2 0.1 0.071 12.4 0.1 1.4 1 0 0 1 1 1 0 KaiC NACHT PF05729.12 OAP57780.1 - 0.046 13.6 0.1 0.13 12.2 0.0 1.7 2 0 0 2 2 2 0 NACHT domain RNA_helicase PF00910.22 OAP57780.1 - 0.074 13.4 0.0 0.17 12.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_16 PF13191.6 OAP57780.1 - 0.12 12.8 0.2 0.5 10.7 0.2 2.1 1 1 0 1 1 1 0 AAA ATPase domain SAPS PF04499.15 OAP57781.1 - 0.034 12.9 1.6 0.044 12.6 1.6 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein HRDC PF00570.23 OAP57781.1 - 0.036 14.0 0.0 0.33 11.0 0.0 2.4 2 0 0 2 2 2 0 HRDC domain NPR3 PF03666.13 OAP57781.1 - 0.11 11.3 1.6 0.14 10.9 1.6 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 AA_permease_2 PF13520.6 OAP57782.1 - 1.1e-63 215.6 49.7 1.3e-63 215.3 49.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAP57782.1 - 4.5e-27 94.8 39.1 6.1e-27 94.3 39.1 1.1 1 0 0 1 1 1 1 Amino acid permease SGL PF08450.12 OAP57783.1 - 0.041 13.5 0.3 1.1 8.8 0.1 2.6 2 1 0 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region Cpn60_TCP1 PF00118.24 OAP57784.1 - 5.3e-84 282.6 12.9 1e-83 281.7 12.9 1.4 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family Rrf2 PF02082.20 OAP57784.1 - 0.073 13.4 0.1 0.23 11.8 0.1 1.9 1 0 0 1 1 1 0 Transcriptional regulator MMU163 PF17119.5 OAP57787.1 - 1.2e-102 342.3 6.0 6.7e-65 218.7 1.1 2.1 1 1 1 2 2 2 2 Mitochondrial protein up-regulated during meiosis Alpha-amylase_C PF02806.18 OAP57788.1 - 3.8e-26 91.4 0.1 9.5e-26 90.1 0.1 1.7 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.18 OAP57788.1 - 4.4e-19 68.6 0.1 1.4e-18 67.0 0.0 2.0 2 0 0 2 2 2 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 OAP57788.1 - 2.4e-14 53.6 0.2 5.3e-11 42.7 0.1 2.2 1 1 1 2 2 2 2 Alpha amylase, catalytic domain hDGE_amylase PF14701.6 OAP57788.1 - 0.17 10.9 0.1 0.62 9.1 0.1 1.8 2 0 0 2 2 2 0 Glycogen debranching enzyme, glucanotransferase domain Hydrolase_4 PF12146.8 OAP57789.1 - 1e-06 28.2 0.1 0.018 14.3 0.0 2.7 1 1 2 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OAP57789.1 - 3.1e-06 27.9 1.1 1.9e-05 25.4 1.1 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 OAP57789.1 - 1.2e-05 24.9 0.0 0.019 14.4 0.0 2.1 1 1 1 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 OAP57789.1 - 0.00098 18.8 0.1 0.0041 16.8 0.0 1.8 1 1 1 2 2 2 1 alpha/beta hydrolase fold DUF915 PF06028.11 OAP57789.1 - 0.0035 16.7 0.0 0.0061 15.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) VirJ PF06057.11 OAP57789.1 - 0.013 15.4 0.0 0.021 14.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) DLH PF01738.18 OAP57789.1 - 0.15 11.6 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family YSIRK_signal PF04650.17 OAP57789.1 - 0.19 11.6 0.4 0.41 10.6 0.4 1.5 1 0 0 1 1 1 0 YSIRK type signal peptide AAA_2 PF07724.14 OAP57790.1 - 2.5e-37 128.6 0.0 2.6e-36 125.3 0.0 2.3 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 OAP57790.1 - 1.8e-14 54.3 0.0 4.2e-14 53.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 OAP57790.1 - 3.4e-07 30.2 0.0 7.8e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 OAP57790.1 - 1.5e-06 28.2 0.0 3.5e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 OAP57790.1 - 0.0001 21.8 0.1 0.01 15.2 0.0 3.1 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 OAP57790.1 - 0.0009 19.0 0.0 0.088 12.5 0.0 2.3 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_22 PF13401.6 OAP57790.1 - 0.0019 18.5 0.5 0.027 14.8 0.3 2.6 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OAP57790.1 - 0.0021 18.5 0.1 0.012 16.0 0.1 2.3 1 1 0 1 1 1 1 AAA ATPase domain IstB_IS21 PF01695.17 OAP57790.1 - 0.0046 16.7 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_24 PF13479.6 OAP57790.1 - 0.0054 16.5 0.0 0.0087 15.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 OAP57790.1 - 0.0073 16.1 0.3 0.1 12.3 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain MCM PF00493.23 OAP57790.1 - 0.0092 15.1 0.3 0.022 13.9 0.1 1.7 2 0 0 2 2 2 1 MCM P-loop domain AAA_7 PF12775.7 OAP57790.1 - 0.041 13.4 0.0 0.075 12.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 OAP57790.1 - 0.056 13.8 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_3 PF07726.11 OAP57790.1 - 0.11 12.3 0.0 0.28 11.0 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 OAP57790.1 - 0.18 11.8 0.0 0.36 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 OAP57790.1 - 0.2 12.2 1.4 0.26 11.8 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_33 PF13671.6 OAP57790.1 - 0.45 10.7 2.1 1.8 8.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain NAD_binding_10 PF13460.6 OAP57791.1 - 7.2e-21 74.9 0.1 9.5e-21 74.5 0.1 1.1 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAP57791.1 - 0.013 15.0 0.0 0.022 14.2 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 OAP57791.1 - 0.097 11.8 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain DUF4202 PF13875.6 OAP57791.1 - 0.18 11.7 0.1 0.28 11.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4202) GST_N_3 PF13417.6 OAP57792.1 - 1e-20 73.9 0.0 2.1e-20 72.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OAP57792.1 - 1.4e-18 66.9 0.3 3.9e-18 65.5 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 OAP57792.1 - 9.7e-14 51.5 0.0 1.9e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAP57792.1 - 1.3e-06 28.3 0.1 2.5e-06 27.4 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 OAP57792.1 - 9.8e-05 22.9 0.0 0.00023 21.7 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OAP57792.1 - 0.0019 18.4 0.0 0.0035 17.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 OAP57792.1 - 0.055 13.7 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 Glutaredoxin GST_C_3 PF14497.6 OAP57792.1 - 0.085 13.1 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain ANAPC10 PF03256.16 OAP57793.1 - 1.4e-37 129.2 0.0 5.1e-37 127.3 0.0 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) DUF2271 PF10029.9 OAP57793.1 - 0.16 11.6 0.1 0.32 10.6 0.1 1.4 1 0 0 1 1 1 0 Predicted periplasmic protein (DUF2271) Cas1_AcylT PF07779.12 OAP57794.1 - 3.2e-113 379.2 14.1 4.4e-113 378.7 14.1 1.0 1 0 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p DUF3494 PF11999.8 OAP57794.1 - 0.057 13.1 0.0 0.096 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3494) MFS_1 PF07690.16 OAP57795.1 - 2.7e-32 112.1 72.5 4.5e-24 85.0 45.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 OAP57795.1 - 0.00072 18.5 1.2 0.00072 18.5 1.2 2.9 1 1 0 2 2 2 2 MFS_1 like family TMIE PF16038.5 OAP57795.1 - 0.21 11.5 0.2 0.21 11.5 0.2 1.8 2 0 0 2 2 2 0 TMIE protein His_Phos_1 PF00300.22 OAP57796.1 - 1.4e-14 54.2 0.8 7.2e-14 51.9 0.8 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) PP2C PF00481.21 OAP57797.1 - 2.9e-37 128.7 0.1 2.3e-30 106.1 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 OAP57797.1 - 0.0039 16.9 0.0 0.01 15.5 0.0 1.7 2 0 0 2 2 2 1 Protein phosphatase 2C CDP-OH_P_transf PF01066.21 OAP57798.1 - 3e-13 50.3 0.8 3e-13 50.3 0.8 2.1 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Abhydrolase_3 PF07859.13 OAP57799.1 - 7.5e-42 143.6 0.0 1.1e-41 143.1 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 OAP57799.1 - 3.9e-05 22.7 0.0 0.00013 21.0 0.0 1.7 1 1 0 1 1 1 1 Carboxylesterase family Mcl1_mid PF12341.8 OAP57800.1 - 2e-95 319.6 0.0 1.9e-94 316.4 0.0 2.2 2 1 0 2 2 2 1 Minichromosome loss protein, Mcl1, middle region WD40 PF00400.32 OAP57800.1 - 3.8e-14 52.8 3.4 0.00022 22.0 0.0 6.3 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAP57800.1 - 4.4e-14 52.6 0.1 0.0006 20.1 0.0 5.6 4 1 1 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 OAP57800.1 - 2.2e-05 23.7 0.0 5.8e-05 22.3 0.0 1.7 2 0 0 2 2 2 1 Coatomer WD associated region eIF2A PF08662.11 OAP57800.1 - 0.0027 17.6 0.3 4.4 7.1 0.1 3.2 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A VID27 PF08553.10 OAP57800.1 - 0.012 14.7 0.0 0.023 13.8 0.0 1.4 1 0 0 1 1 1 0 VID27 C-terminal WD40-like domain PD40 PF07676.12 OAP57800.1 - 0.026 14.5 0.1 32 4.6 0.0 4.3 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat DNA_pol_alpha_N PF12254.8 OAP57800.1 - 0.044 13.9 1.0 0.099 12.7 1.0 1.5 1 0 0 1 1 1 0 DNA polymerase alpha subunit p180 N terminal IKI3 PF04762.12 OAP57800.1 - 0.12 10.4 0.0 0.17 9.8 0.0 1.2 1 0 0 1 1 1 0 IKI3 family Cytochrom_D1 PF02239.16 OAP57800.1 - 0.15 10.5 0.0 0.99 7.9 0.0 2.1 2 0 0 2 2 2 0 Cytochrome D1 heme domain BBS2_Mid PF14783.6 OAP57800.1 - 0.19 11.7 0.0 7.8 6.6 0.0 2.5 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region Nucleoporin_N PF08801.11 OAP57800.1 - 0.23 10.1 0.0 0.57 8.9 0.0 1.6 1 0 0 1 1 1 0 Nup133 N terminal like OTT_1508_deam PF14441.6 OAP57801.1 - 4.7e-12 45.7 5.0 4.1e-11 42.7 4.0 2.6 2 0 0 2 2 2 1 OTT_1508-like deaminase DUF1275 PF06912.11 OAP57802.1 - 1.9e-43 148.6 12.9 2.3e-43 148.4 12.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) DUF4267 PF14087.6 OAP57802.1 - 0.064 13.3 6.7 0.21 11.7 1.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4267) COesterase PF00135.28 OAP57803.1 - 7.6e-73 246.1 0.0 1e-72 245.7 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAP57803.1 - 7.6e-09 35.7 0.3 9.4e-08 32.2 0.3 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OAP57803.1 - 0.0091 15.5 0.2 0.018 14.6 0.2 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Say1_Mug180 PF10340.9 OAP57803.1 - 0.17 10.7 0.0 11 4.8 0.0 2.1 2 0 0 2 2 2 0 Steryl acetyl hydrolase Fungal_trans PF04082.18 OAP57804.1 - 4.8e-15 55.3 1.0 7.4e-15 54.7 1.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP57804.1 - 7.8e-09 35.5 7.1 1.6e-08 34.5 7.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 OAP57806.1 - 4.1e-37 127.9 23.5 4.1e-37 127.9 23.5 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAP57806.1 - 2.9e-08 33.0 2.2 2.9e-08 33.0 2.2 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter LacY_symp PF01306.19 OAP57806.1 - 6.1e-05 22.0 1.1 6.1e-05 22.0 1.1 2.1 1 1 0 2 2 2 1 LacY proton/sugar symporter Peptidase_M19 PF01244.21 OAP57807.1 - 1.2e-94 317.0 0.0 1.6e-94 316.7 0.0 1.1 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Fructosamin_kin PF03881.14 OAP57807.1 - 6.5e-71 238.9 0.0 1.6e-70 237.6 0.0 1.5 1 1 0 1 1 1 1 Fructosamine kinase APH PF01636.23 OAP57807.1 - 7.3e-07 29.4 0.0 1.4e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 OAP57807.1 - 0.022 13.6 0.0 0.034 13.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) UFD1 PF03152.14 OAP57808.1 - 1.7e-73 245.8 0.0 2.1e-73 245.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CDC48_2 PF02933.17 OAP57808.1 - 0.067 13.0 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), domain 2 GYF PF02213.16 OAP57809.1 - 1.4e-12 47.1 2.1 3.6e-12 45.8 2.1 1.7 1 0 0 1 1 1 1 GYF domain gp12-short_mid PF09089.10 OAP57809.1 - 0.078 13.2 0.6 3.1 8.0 0.0 2.5 2 0 0 2 2 2 0 Phage short tail fibre protein gp12, middle domain dCMP_cyt_deam_1 PF00383.23 OAP57810.1 - 3.6e-08 33.2 1.9 3.6e-07 30.0 1.9 2.1 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 OAP57810.1 - 3.8e-05 23.4 0.9 0.00033 20.4 0.2 2.2 2 0 0 2 2 2 1 MafB19-like deaminase DUF202 PF02656.15 OAP57811.1 - 7.3e-05 23.1 8.6 0.00078 19.8 8.6 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF202) Fungal_trans PF04082.18 OAP57812.1 - 8.1e-13 48.0 1.1 1.3e-12 47.4 1.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.6 OAP57812.1 - 7.6e-07 29.3 2.0 7.6e-07 29.3 2.0 3.6 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 OAP57812.1 - 4.8e-06 27.0 10.7 0.0017 19.0 1.1 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 OAP57812.1 - 8e-05 22.9 12.6 0.013 15.9 3.8 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 OAP57812.1 - 0.022 15.1 1.9 3 8.2 0.3 2.5 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-Di19 PF05605.12 OAP57812.1 - 0.06 13.6 3.3 0.086 13.1 0.1 2.2 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.6 OAP57812.1 - 0.29 10.9 8.8 0.13 12.0 0.3 2.8 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 OAP57812.1 - 0.47 10.8 3.5 3.3 8.1 1.1 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding TRI12 PF06609.13 OAP57813.1 - 8.5e-49 166.5 26.9 1.1e-48 166.1 26.9 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAP57813.1 - 1.2e-20 73.7 54.8 2e-20 73.0 48.0 2.7 2 2 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAP57813.1 - 5.7e-11 41.9 17.0 5.7e-11 41.9 17.0 3.2 2 2 2 4 4 4 1 Sugar (and other) transporter DUF3522 PF12036.8 OAP57813.1 - 0.033 14.5 1.6 0.033 14.5 1.6 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF3522) TIP49 PF06068.13 OAP57814.1 - 1.2e-152 508.1 1.7 1.9e-152 507.5 1.7 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 OAP57814.1 - 2.1e-21 75.8 2.7 2.4e-21 75.6 0.8 2.2 3 0 0 3 3 2 1 TIP49 AAA-lid domain AAA PF00004.29 OAP57814.1 - 5.3e-09 36.6 0.8 5.5e-06 26.8 0.0 3.0 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 OAP57814.1 - 4.1e-08 33.1 0.4 3.9e-05 23.4 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 OAP57814.1 - 3.3e-06 27.6 0.4 1e-05 26.0 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain DnaB_C PF03796.15 OAP57814.1 - 2.3e-05 23.9 0.6 4.8e-05 22.8 0.6 1.5 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain Mg_chelatase PF01078.21 OAP57814.1 - 0.0029 17.0 0.7 0.03 13.7 0.3 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 OAP57814.1 - 0.0031 17.8 1.2 0.087 13.2 1.2 2.4 1 1 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 OAP57814.1 - 0.0076 16.0 0.0 1.9 8.2 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain Parvo_NS1 PF01057.17 OAP57814.1 - 0.013 14.6 0.0 0.022 13.9 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_5 PF07728.14 OAP57814.1 - 0.019 15.0 0.0 0.35 10.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 OAP57814.1 - 0.037 13.6 0.1 0.069 12.7 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 OAP57814.1 - 0.056 13.0 0.2 0.4 10.2 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_33 PF13671.6 OAP57814.1 - 0.065 13.4 0.0 0.24 11.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_32 PF13654.6 OAP57814.1 - 0.082 11.7 1.0 0.13 11.0 0.0 1.7 3 0 0 3 3 3 0 AAA domain AAA_11 PF13086.6 OAP57814.1 - 0.094 12.5 0.8 0.53 10.0 0.8 2.1 1 1 0 1 1 1 0 AAA domain Hydin_ADK PF17213.3 OAP57814.1 - 0.48 10.7 3.1 0.26 11.5 0.3 2.0 2 1 0 2 2 2 0 Hydin Adenylate kinase-like domain DUF948 PF06103.11 OAP57815.1 - 0.02 15.1 1.1 0.19 12.0 0.3 2.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Shugoshin_N PF07558.11 OAP57815.1 - 0.15 11.9 1.9 18 5.3 0.1 3.1 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region Rsa3 PF14615.6 OAP57815.1 - 0.18 11.4 0.2 48 3.6 0.1 3.3 3 0 0 3 3 3 0 Ribosome-assembly protein 3 Peptidase_S49 PF01343.18 OAP57815.1 - 0.7 9.8 5.4 0.21 11.5 2.0 1.9 2 0 0 2 2 2 0 Peptidase family S49 Baculo_PEP_C PF04513.12 OAP57815.1 - 0.77 9.8 6.6 0.5 10.4 1.2 2.9 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus FlaC_arch PF05377.11 OAP57815.1 - 1.1 9.7 9.7 8.1 6.9 0.1 4.1 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) GLTSCR1 PF15249.6 OAP57815.1 - 2.4 8.6 11.9 0.99 9.9 6.6 2.9 2 1 0 2 2 2 0 Conserved region of unknown function on GLTSCR protein COG5 PF10392.9 OAP57815.1 - 3.9 7.7 10.9 0.12 12.6 3.2 2.5 3 0 0 3 3 3 0 Golgi transport complex subunit 5 KxDL PF10241.9 OAP57815.1 - 8 6.8 11.5 0.34 11.2 1.3 3.5 2 2 0 3 3 3 0 Uncharacterized conserved protein PhyH PF05721.13 OAP57816.1 - 1.4e-27 97.3 0.0 1.9e-27 96.9 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) HGWP PF03578.15 OAP57816.1 - 0.052 13.1 0.0 0.099 12.2 0.0 1.5 1 0 0 1 1 1 0 HGWP repeat DUF1479 PF07350.12 OAP57816.1 - 0.22 10.2 0.0 0.3 9.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1479) Ge1_WD40 PF16529.5 OAP57818.1 - 0.0033 16.4 0.0 0.017 14.1 0.0 2.1 1 1 0 1 1 1 1 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF445 PF04286.12 OAP57818.1 - 1.7 8.4 11.2 0.16 11.8 4.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF445) Chs7 PF12271.8 OAP57819.1 - 1.4e-109 365.9 9.4 1.6e-109 365.8 9.4 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone YvrJ PF12841.7 OAP57819.1 - 0.061 12.9 0.1 0.14 11.7 0.1 1.5 1 0 0 1 1 1 0 YvrJ protein family Cytochrom_B_C PF00032.17 OAP57819.1 - 0.54 10.6 8.6 0.16 12.3 0.5 2.9 2 2 0 2 2 2 0 Cytochrome b(C-terminal)/b6/petD HET PF06985.11 OAP57820.1 - 3.7e-27 95.5 0.3 6.5e-27 94.7 0.3 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Macoilin PF09726.9 OAP57821.1 - 1 7.8 7.3 1.5 7.3 7.3 1.2 1 0 0 1 1 1 0 Macoilin family FMO-like PF00743.19 OAP57822.1 - 1.2e-15 57.0 0.2 5.1e-14 51.6 0.0 2.1 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 OAP57822.1 - 7.7e-13 48.3 0.0 1e-10 41.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAP57822.1 - 2.5e-12 46.7 0.0 3.5e-11 42.9 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAP57822.1 - 2e-08 33.8 0.0 8.5e-07 28.4 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 OAP57822.1 - 4.1e-05 23.3 2.8 0.0057 16.3 0.1 3.7 2 1 2 4 4 4 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAP57822.1 - 7.5e-05 22.9 0.0 0.00036 20.7 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 OAP57822.1 - 0.00043 20.3 1.3 0.23 11.4 0.4 4.0 3 1 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 OAP57822.1 - 0.011 16.3 0.1 9.8 6.8 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 OAP57822.1 - 0.056 13.9 0.0 23 5.5 0.0 2.7 2 0 0 2 2 2 0 Putative NAD(P)-binding Lycopene_cycl PF05834.12 OAP57822.1 - 0.081 12.0 0.2 2.4 7.1 0.1 2.8 3 0 0 3 3 3 0 Lycopene cyclase protein DUF1902 PF08972.11 OAP57822.1 - 0.16 12.0 1.0 0.33 11.0 1.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1902) Peptidase_M16 PF00675.20 OAP57823.1 - 1.5e-15 57.5 0.0 2.8e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 OAP57823.1 - 1.8e-10 41.2 0.0 3.1e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase M16 inactive domain PALB2_WD40 PF16756.5 OAP57823.1 - 0.18 10.7 0.0 0.27 10.1 0.0 1.2 1 0 0 1 1 1 0 Partner and localizer of BRCA2 WD40 domain TFIIE_alpha PF02002.17 OAP57824.1 - 0.00012 21.8 0.3 0.0011 18.8 0.2 2.3 2 0 0 2 2 2 1 TFIIE alpha subunit RNA_pol_Rpc82 PF05645.13 OAP57824.1 - 0.00046 20.0 0.0 0.08 12.7 0.0 3.6 2 1 0 2 2 2 1 RNA polymerase III subunit RPC82 ATP-synt_Eps PF04627.13 OAP57825.1 - 7.2e-23 80.3 0.5 9.5e-23 79.9 0.5 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain Mak10 PF04112.13 OAP57826.1 - 1.5e-55 187.3 0.0 2.8e-55 186.4 0.0 1.5 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Brix PF04427.18 OAP57827.1 - 1.9e-32 113.0 0.0 2.4e-32 112.6 0.0 1.1 1 0 0 1 1 1 1 Brix domain Aldo_ket_red PF00248.21 OAP57828.1 - 2.4e-49 168.1 0.0 2.7e-49 167.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family F-box-like PF12937.7 OAP57830.1 - 5.6e-06 26.1 0.4 3.4e-05 23.6 0.1 2.5 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 OAP57830.1 - 0.034 14.0 0.1 0.092 12.6 0.1 1.7 1 0 0 1 1 1 0 F-box domain Pyr_redox_2 PF07992.14 OAP57831.1 - 8.6e-13 48.2 0.0 2.6e-10 40.0 0.0 2.6 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 OAP57831.1 - 3.2e-09 35.8 0.0 9.3e-06 24.3 0.0 2.8 2 1 1 3 3 3 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OAP57831.1 - 8.3e-09 35.1 0.0 1.1e-07 31.4 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAP57831.1 - 4e-05 23.7 0.5 0.00013 22.2 0.2 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.20 OAP57831.1 - 0.042 13.9 0.1 0.14 12.3 0.0 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Aldolase_II PF00596.21 OAP57832.1 - 3.4e-48 164.1 0.0 4.6e-48 163.6 0.0 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain ADH_N PF08240.12 OAP57833.1 - 4.9e-26 90.7 1.6 1.2e-25 89.5 1.6 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAP57833.1 - 4.8e-20 71.9 0.0 7.7e-20 71.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TrkA_N PF02254.18 OAP57833.1 - 0.001 19.3 0.1 0.0018 18.6 0.1 1.3 1 0 0 1 1 1 1 TrkA-N domain FAD_binding_3 PF01494.19 OAP57833.1 - 0.0039 16.5 0.3 0.0069 15.7 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain Glu_dehyd_C PF16912.5 OAP57833.1 - 0.005 16.4 0.1 0.032 13.7 0.0 2.0 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus Shikimate_DH PF01488.20 OAP57833.1 - 0.056 13.5 0.0 0.094 12.8 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ADH_zinc_N_2 PF13602.6 OAP57833.1 - 0.079 14.0 0.1 0.24 12.4 0.1 1.8 1 1 1 2 2 2 0 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 OAP57833.1 - 0.11 11.8 0.1 0.17 11.1 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain F420_oxidored PF03807.17 OAP57833.1 - 0.13 12.8 0.1 0.24 12.0 0.1 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent RecR PF02132.15 OAP57833.1 - 0.31 10.7 1.0 43 3.8 0.2 3.1 3 0 0 3 3 3 0 RecR protein Fungal_trans PF04082.18 OAP57834.1 - 1.3e-17 63.7 0.0 2.2e-17 63.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP57834.1 - 1.3e-06 28.4 8.2 2.4e-06 27.6 8.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FMO-like PF00743.19 OAP57835.1 - 5.4e-14 51.5 0.0 2.5e-13 49.3 0.0 1.8 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 OAP57835.1 - 1.5e-08 34.2 0.0 5.8e-07 29.0 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAP57835.1 - 1.8e-08 34.0 0.0 4.3e-08 32.8 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAP57835.1 - 1.1e-06 28.7 0.1 7.1e-06 26.2 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 OAP57835.1 - 2.5e-05 23.6 0.0 0.00012 21.3 0.0 2.0 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 OAP57835.1 - 0.015 15.8 0.1 2.8 8.6 0.1 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAP57835.1 - 0.016 14.8 0.1 8.2 5.9 0.0 3.1 2 1 1 3 3 3 0 FAD dependent oxidoreductase Shikimate_DH PF01488.20 OAP57835.1 - 0.03 14.4 0.4 0.34 11.0 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.6 OAP57835.1 - 0.031 14.3 0.3 1.2 9.1 0.0 3.2 3 1 0 3 3 3 0 FAD-NAD(P)-binding 2-Hacid_dh_C PF02826.19 OAP57835.1 - 0.035 13.5 0.0 0.064 12.6 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 OAP57835.1 - 0.12 12.9 0.0 16 6.0 0.0 2.7 2 0 0 2 2 2 0 Putative NAD(P)-binding Sugar_tr PF00083.24 OAP57836.1 - 6.2e-94 315.4 25.9 7.4e-94 315.1 25.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP57836.1 - 7e-21 74.5 23.5 7e-21 74.5 23.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1672 PF07901.11 OAP57836.1 - 0.077 12.3 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1672) Aldedh PF00171.22 OAP57837.1 - 9.5e-135 449.7 0.0 1.2e-134 449.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family OmdA PF13376.6 OAP57837.1 - 1.4 9.0 3.0 1.7 8.7 0.3 2.2 2 0 0 2 2 2 0 Bacteriocin-protection, YdeI or OmpD-Associated Ras PF00071.22 OAP57838.1 - 3.3e-63 212.1 0.3 3.9e-63 211.9 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAP57838.1 - 2.7e-35 121.2 0.2 3.8e-35 120.7 0.2 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAP57838.1 - 2.8e-13 49.7 0.1 3.7e-13 49.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OAP57838.1 - 5.6e-08 32.9 0.1 8.6e-08 32.3 0.1 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OAP57838.1 - 8.7e-05 22.5 0.2 0.014 15.3 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 OAP57838.1 - 0.00012 21.7 0.2 0.00057 19.5 0.1 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OAP57838.1 - 0.00048 19.5 0.1 0.00076 18.9 0.1 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 OAP57838.1 - 0.0043 17.3 0.0 0.032 14.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain SRPRB PF09439.10 OAP57838.1 - 0.016 14.6 0.0 0.024 14.0 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_14 PF13173.6 OAP57838.1 - 0.018 15.1 0.1 0.061 13.4 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 OAP57838.1 - 0.019 15.3 0.1 0.032 14.6 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 OAP57838.1 - 0.023 15.2 0.1 0.032 14.7 0.1 1.5 1 1 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 OAP57838.1 - 0.024 14.4 0.1 0.06 13.1 0.1 1.7 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 OAP57838.1 - 0.041 13.3 0.0 0.16 11.3 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein FeoB_N PF02421.18 OAP57838.1 - 0.089 12.3 0.1 0.22 11.0 0.0 1.6 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_7 PF12775.7 OAP57838.1 - 0.092 12.3 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region SpoIIID PF12116.8 OAP57838.1 - 0.13 12.4 0.1 2.4 8.3 0.0 2.2 2 0 0 2 2 2 0 Stage III sporulation protein D AAA_21 PF13304.6 OAP57838.1 - 0.14 12.0 0.6 0.23 11.2 0.4 1.5 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Chromo PF00385.24 OAP57839.1 - 2.6e-07 30.4 0.0 6.8e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Cyclin PF08613.11 OAP57840.1 - 4.9e-31 108.3 0.0 1.1e-30 107.1 0.0 1.5 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 OAP57840.1 - 2.5e-05 24.0 0.0 4.4e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain ORC6 PF05460.13 OAP57840.1 - 3.5 6.8 12.2 6 6.0 12.2 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) HEAT_2 PF13646.6 OAP57841.1 - 0.00018 21.8 9.1 0.00055 20.3 0.9 5.0 5 2 0 5 5 5 1 HEAT repeats Arm PF00514.23 OAP57841.1 - 0.00048 20.1 18.7 0.062 13.4 0.1 7.6 9 0 0 9 9 9 2 Armadillo/beta-catenin-like repeat HEAT PF02985.22 OAP57841.1 - 0.0036 17.4 15.7 0.4 11.1 0.0 7.3 7 0 0 7 7 7 1 HEAT repeat WAPL PF07814.13 OAP57841.1 - 0.0081 15.0 0.8 0.035 12.9 0.0 2.3 3 1 0 3 3 3 1 Wings apart-like protein regulation of heterochromatin DUF3535 PF12054.8 OAP57841.1 - 0.037 13.3 2.2 0.031 13.5 0.5 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3535) DUF3361 PF11841.8 OAP57841.1 - 0.064 13.2 0.9 0.19 11.6 0.9 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3361) TAF6_C PF07571.13 OAP57841.1 - 0.12 12.8 1.2 16 5.9 0.0 3.9 2 2 1 3 3 3 0 TAF6 C-terminal HEAT repeat domain V-ATPase_H_C PF11698.8 OAP57841.1 - 0.12 12.5 0.1 14 5.8 0.0 3.0 2 1 1 3 3 3 0 V-ATPase subunit H SR-25 PF10500.9 OAP57842.1 - 0.17 11.5 14.0 0.26 10.9 14.0 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein UPF0561 PF10573.9 OAP57842.1 - 0.19 11.8 2.4 0.54 10.4 2.4 1.7 1 0 0 1 1 1 0 Uncharacterised protein family UPF0561 AF-4 PF05110.13 OAP57842.1 - 0.97 7.4 10.9 1.3 7.0 10.9 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein CBFD_NFYB_HMF PF00808.23 OAP57843.1 - 2e-05 24.8 0.1 2.6e-05 24.4 0.1 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-W PF15510.6 OAP57843.1 - 0.00033 20.8 0.1 0.0004 20.5 0.1 1.1 1 0 0 1 1 1 1 CENP-W protein Vip3A_N PF12495.8 OAP57844.1 - 0.016 15.1 0.4 0.029 14.3 0.4 1.4 1 0 0 1 1 1 0 Vegetative insecticide protein 3A N terminal APP_E2 PF12925.7 OAP57844.1 - 0.092 12.5 8.7 0.2 11.3 8.7 1.6 1 1 0 1 1 1 0 E2 domain of amyloid precursor protein AAA_23 PF13476.6 OAP57844.1 - 0.12 12.9 4.4 0.23 12.0 4.4 1.5 1 0 0 1 1 1 0 AAA domain DUF1690 PF07956.11 OAP57844.1 - 2.7 8.4 10.7 1.3 9.4 4.2 3.1 1 1 2 3 3 3 0 Protein of Unknown function (DUF1690) Ax_dynein_light PF10211.9 OAP57844.1 - 3.2 7.7 12.7 2 8.3 10.2 1.9 2 0 0 2 2 2 0 Axonemal dynein light chain PQQ_3 PF13570.6 OAP57845.1 - 0.27 11.8 1.8 6 7.5 0.1 2.9 3 0 0 3 3 3 0 PQQ-like domain Pex16 PF08610.10 OAP57847.1 - 9.6e-130 432.5 0.9 1.1e-129 432.3 0.9 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) ASXH PF13919.6 OAP57848.1 - 1.1e-17 64.3 0.0 1.4e-17 64.0 0.0 1.1 1 0 0 1 1 1 1 Asx homology domain Myb_DNA-binding PF00249.31 OAP57849.1 - 2.6e-15 56.3 3.0 1.9e-12 47.2 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OAP57849.1 - 8.3e-08 32.4 3.8 5.2e-06 26.6 0.2 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Methyltransf_11 PF08241.12 OAP57850.1 - 9.5e-13 48.6 0.0 1.5e-12 47.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAP57850.1 - 2.4e-11 44.2 0.0 4e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAP57850.1 - 1.3e-08 34.8 0.0 7.7e-07 29.1 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAP57850.1 - 1.8e-07 31.1 0.0 2.9e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAP57850.1 - 3.5e-05 24.5 0.0 7.5e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 OAP57850.1 - 0.0063 15.5 0.1 0.023 13.6 0.1 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1698) MetW PF07021.12 OAP57850.1 - 0.1 12.2 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW TIG PF01833.24 OAP57851.1 - 8.3e-11 41.8 0.3 3.4e-10 39.9 0.1 2.2 2 0 0 2 2 2 1 IPT/TIG domain Ank_4 PF13637.6 OAP57851.1 - 1.7e-07 31.6 0.6 4.1e-07 30.4 0.6 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 OAP57851.1 - 3.6e-07 30.7 0.0 7.1e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 OAP57851.1 - 9.1e-07 29.1 6.6 0.011 16.2 0.4 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 OAP57851.1 - 2.1e-06 27.9 0.2 5.2e-06 26.6 0.2 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAP57851.1 - 5.3e-06 26.4 1.2 0.18 12.5 0.2 2.7 2 0 0 2 2 2 2 Ankyrin repeat RHD_dimer PF16179.5 OAP57851.1 - 0.06 13.4 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 Rel homology dimerisation domain adh_short_C2 PF13561.6 OAP57852.1 - 7.9e-36 123.8 0.0 9.5e-36 123.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP57852.1 - 1e-26 93.6 0.0 1.3e-26 93.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 OAP57852.1 - 4.9e-07 29.4 0.0 1.5e-06 27.8 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.10 OAP57852.1 - 8.1e-07 29.1 0.1 0.00017 21.5 0.0 2.5 2 1 0 2 2 2 1 KR domain 3Beta_HSD PF01073.19 OAP57852.1 - 0.00025 20.2 0.0 0.00048 19.2 0.0 1.4 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 OAP57852.1 - 0.0065 15.9 0.1 0.02 14.3 0.0 1.8 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 OAP57852.1 - 0.0087 15.2 0.0 0.014 14.5 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 OAP57852.1 - 0.029 14.2 0.0 0.046 13.6 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding NmrA PF05368.13 OAP57852.1 - 0.031 13.8 0.0 0.048 13.2 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family DUF1295 PF06966.12 OAP57853.1 - 3.4e-13 49.7 0.2 4.3e-13 49.3 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 OAP57853.1 - 4.1e-06 26.9 0.1 5.4e-06 26.4 0.1 1.3 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase ERG4_ERG24 PF01222.17 OAP57853.1 - 0.00046 19.1 1.2 0.00074 18.4 0.6 1.6 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family PEMT PF04191.13 OAP57853.1 - 0.00093 19.6 1.0 0.0055 17.1 0.3 2.3 1 1 1 2 2 2 1 Phospholipid methyltransferase NnrU PF07298.11 OAP57853.1 - 0.0019 17.7 0.1 0.0044 16.5 0.0 1.5 1 1 0 1 1 1 1 NnrU protein ICMT PF04140.14 OAP57853.1 - 0.11 12.9 0.0 0.23 11.9 0.0 1.6 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family DUF4079 PF13301.6 OAP57854.1 - 1.3e-05 25.4 2.6 0.24 11.6 0.1 3.1 2 1 1 3 3 3 2 Protein of unknown function (DUF4079) TM140 PF14985.6 OAP57854.1 - 0.029 13.9 3.1 0.2 11.2 0.1 2.1 2 0 0 2 2 2 0 TM140 protein family Cytochrom_B561 PF03188.16 OAP57854.1 - 0.081 13.1 6.3 0.087 13.0 3.5 2.3 1 1 1 2 2 2 0 Eukaryotic cytochrome b561 DUF4668 PF15701.5 OAP57854.1 - 0.24 11.2 0.8 1.2 8.9 0.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4668) zf-CCHC PF00098.23 OAP57855.1 - 1.1e-34 116.9 45.2 1.4e-08 34.4 4.0 5.3 5 0 0 5 5 5 5 Zinc knuckle zf-CCHC_4 PF14392.6 OAP57855.1 - 1.6e-05 24.5 28.1 0.18 11.6 0.8 5.1 5 0 0 5 5 5 5 Zinc knuckle zf-CCHC_5 PF14787.6 OAP57855.1 - 1.8e-05 24.4 25.6 0.049 13.4 1.3 4.5 4 0 0 4 4 4 4 GAG-polyprotein viral zinc-finger zf-CCHC_3 PF13917.6 OAP57855.1 - 0.00085 19.2 28.6 0.092 12.7 0.6 5.0 3 1 2 5 5 5 4 Zinc knuckle zf-CCHC_6 PF15288.6 OAP57855.1 - 0.042 13.7 33.3 0.41 10.5 0.4 5.4 4 1 1 5 5 5 0 Zinc knuckle zf-CCHC_2 PF13696.6 OAP57855.1 - 0.052 13.4 2.4 0.052 13.4 2.4 4.5 4 0 0 4 4 4 0 Zinc knuckle F-box-like PF12937.7 OAP57856.1 - 5.6e-08 32.6 0.1 1.2e-07 31.6 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAP57856.1 - 9.4e-08 31.7 1.7 1.8e-07 30.8 1.7 1.5 1 0 0 1 1 1 1 F-box domain SAE2 PF08573.10 OAP57857.1 - 1.1e-23 84.4 0.0 1.1e-23 84.4 0.0 3.4 3 1 0 3 3 2 1 DNA repair protein endonuclease SAE2/CtIP C-terminus Geminin PF07412.12 OAP57857.1 - 0.0036 17.1 2.6 0.0086 15.8 2.6 1.7 1 0 0 1 1 1 1 Geminin Cnn_1N PF07989.11 OAP57857.1 - 0.014 15.5 7.5 0.014 15.5 7.5 2.1 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 HALZ PF02183.18 OAP57857.1 - 0.032 14.5 2.5 0.032 14.5 2.5 2.8 2 1 0 2 2 2 0 Homeobox associated leucine zipper Atg14 PF10186.9 OAP57857.1 - 0.046 12.8 15.7 0.018 14.1 12.4 1.8 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Phage_GP20 PF06810.11 OAP57857.1 - 0.089 12.6 5.0 0.28 11.0 4.9 1.9 1 1 0 1 1 1 0 Phage minor structural protein GP20 FapA PF03961.13 OAP57857.1 - 0.35 9.4 3.7 0.57 8.7 3.7 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A TMEM192 PF14802.6 OAP57857.1 - 0.38 9.8 1.0 0.6 9.2 1.0 1.3 1 0 0 1 1 1 0 TMEM192 family CENP-H PF05837.12 OAP57857.1 - 0.69 10.3 17.0 0.043 14.2 9.4 2.7 3 0 0 3 3 3 0 Centromere protein H (CENP-H) DUF641 PF04859.12 OAP57857.1 - 1.3 9.3 8.6 0.54 10.6 5.0 2.1 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) TMPIT PF07851.13 OAP57857.1 - 2 7.6 3.8 3.3 6.8 3.8 1.4 1 0 0 1 1 1 0 TMPIT-like protein YabA PF06156.13 OAP57857.1 - 2.8 8.6 13.4 0.86 10.3 2.6 3.1 2 1 1 3 3 3 0 Initiation control protein YabA UPF0242 PF06785.11 OAP57857.1 - 3.3 7.8 19.3 0.068 13.3 10.3 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus PRKG1_interact PF15898.5 OAP57857.1 - 5 8.1 17.9 0.75 10.7 2.0 3.4 2 1 1 3 3 3 0 cGMP-dependent protein kinase interacting domain ADIP PF11559.8 OAP57857.1 - 10 6.2 18.5 4 7.5 12.6 2.6 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding SR-25 PF10500.9 OAP57858.1 - 2.1 7.9 20.0 3.3 7.3 20.0 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SRF-TF PF00319.18 OAP57859.1 - 0.028 13.9 0.0 0.25 10.8 0.0 2.4 3 0 0 3 3 3 0 SRF-type transcription factor (DNA-binding and dimerisation domain) AMP-binding PF00501.28 OAP57860.1 - 1.8e-73 247.6 0.0 2.2e-73 247.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAP57860.1 - 7.8e-11 42.8 0.0 2.1e-10 41.4 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain CAP_GLY PF01302.25 OAP57861.1 - 1.2e-18 66.8 2.5 2.4e-18 65.9 2.5 1.5 1 1 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.6 OAP57861.1 - 6.7e-14 52.1 0.0 1.5e-13 51.0 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.23 OAP57861.1 - 0.0015 18.2 0.0 0.0035 17.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family CENP-C_C PF11699.8 OAP57862.1 - 2.4e-29 101.4 0.1 5.1e-29 100.3 0.1 1.6 1 0 0 1 1 1 1 Mif2/CENP-C like Mif2_N PF15624.6 OAP57862.1 - 1.4e-20 74.4 8.9 1.4e-20 74.4 8.9 3.5 3 1 1 4 4 4 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Cupin_2 PF07883.11 OAP57862.1 - 9.3e-06 25.3 0.0 1.8e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 OAP57862.1 - 0.0049 16.5 0.1 0.0086 15.7 0.1 1.3 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.12 OAP57862.1 - 0.097 12.4 0.1 0.25 11.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF861) RNase_HII PF01351.18 OAP57863.1 - 1.1e-48 165.8 0.0 1.6e-48 165.2 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease HII FMN_dh PF01070.18 OAP57864.1 - 4e-103 345.1 0.0 4.8e-103 344.8 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 OAP57864.1 - 4.9e-17 61.8 0.0 1e-16 60.8 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 OAP57864.1 - 8.2e-08 31.8 0.2 1.2e-07 31.2 0.2 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 OAP57864.1 - 1.5e-06 27.4 0.0 1.8e-05 24.0 0.1 2.0 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 OAP57864.1 - 0.021 14.2 1.2 0.044 13.2 1.2 1.4 1 0 0 1 1 1 0 Nitronate monooxygenase His_biosynth PF00977.21 OAP57864.1 - 0.042 13.3 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 Histidine biosynthesis protein DHO_dh PF01180.21 OAP57864.1 - 0.049 12.8 0.1 0.082 12.1 0.1 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase ThiG PF05690.14 OAP57864.1 - 0.14 11.5 0.2 0.3 10.4 0.1 1.6 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG Ribul_P_3_epim PF00834.19 OAP57864.1 - 0.2 11.0 0.0 0.28 10.5 0.0 1.2 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family p450 PF00067.22 OAP57865.1 - 3.9e-52 177.5 0.0 5.1e-52 177.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 OAP57866.1 - 4.4e-45 154.1 65.9 4.6e-39 134.3 53.1 3.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAP57866.1 - 5.4e-08 32.1 8.8 5.4e-08 32.1 8.8 2.9 1 1 2 4 4 4 2 Sugar (and other) transporter Cauli_VI PF01693.16 OAP57867.1 - 4.9e-37 126.0 7.0 3.9e-19 68.7 1.2 2.6 2 0 0 2 2 2 2 Caulimovirus viroplasmin RNase_H PF00075.24 OAP57867.1 - 9.1e-31 107.0 1.6 8.5e-27 94.1 0.3 2.8 3 0 0 3 3 3 2 RNase H RVT_3 PF13456.6 OAP57867.1 - 0.041 13.7 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 Reverse transcriptase-like Na_H_Exchanger PF00999.21 OAP57868.1 - 8.5e-46 156.5 16.1 1.1e-45 156.1 16.1 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family 6PF2K PF01591.18 OAP57869.1 - 2.6e-67 226.4 0.6 7.7e-48 162.7 0.3 2.2 2 0 0 2 2 2 2 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 OAP57869.1 - 3.6e-28 98.6 0.0 4.6e-21 75.4 0.0 2.8 3 0 0 3 3 3 2 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 OAP57869.1 - 5.6e-05 23.3 0.1 0.3 11.2 0.1 2.3 2 0 0 2 2 2 2 AAA domain KTI12 PF08433.10 OAP57869.1 - 0.037 13.5 0.0 0.74 9.2 0.0 2.2 2 0 0 2 2 2 0 Chromatin associated protein KTI12 WLM PF08325.10 OAP57870.1 - 1.1e-49 169.1 0.0 1.8e-49 168.4 0.0 1.3 1 0 0 1 1 1 1 WLM domain DUF45 PF01863.17 OAP57870.1 - 0.039 14.0 0.3 0.16 12.0 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function DUF45 Cu_amine_oxid PF01179.20 OAP57871.1 - 2.6e-165 550.3 0.0 3.2e-165 550.0 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.16 OAP57871.1 - 6.2e-05 23.1 0.5 0.00012 22.3 0.1 1.7 2 0 0 2 2 2 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.16 OAP57871.1 - 0.00016 22.0 0.0 0.00042 20.7 0.0 1.7 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Rad51 PF08423.11 OAP57872.1 - 1.4e-41 142.5 0.0 5e-40 137.4 0.0 2.1 1 1 0 1 1 1 1 Rad51 AAA_25 PF13481.6 OAP57872.1 - 9.3e-07 28.6 0.0 1.7e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 OAP57872.1 - 0.00042 19.8 0.0 0.0017 17.7 0.0 1.9 1 1 0 1 1 1 1 KaiC RecA PF00154.21 OAP57872.1 - 0.0027 17.2 0.1 0.26 10.7 0.0 2.2 2 0 0 2 2 2 2 recA bacterial DNA recombination protein DnaB_C PF03796.15 OAP57872.1 - 0.0059 16.0 0.1 0.51 9.6 0.1 2.4 1 1 0 1 1 1 1 DnaB-like helicase C terminal domain HU-CCDC81_euk_2 PF18289.1 OAP57872.1 - 0.19 11.9 0.0 0.35 11.1 0.0 1.3 1 0 0 1 1 1 0 CCDC81 eukaryotic HU domain 2 Peptidase_S9 PF00326.21 OAP57873.1 - 1e-45 155.8 0.0 1.5e-45 155.3 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 OAP57873.1 - 4.4e-11 42.7 1.9 1.3e-10 41.2 0.3 2.3 2 1 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S15 PF02129.18 OAP57873.1 - 2.3e-10 40.5 0.1 2.1e-06 27.5 0.4 2.4 2 0 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 OAP57873.1 - 2.6e-08 33.4 0.3 0.0011 18.3 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OAP57873.1 - 1.6e-07 31.2 0.3 0.0022 17.7 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold COesterase PF00135.28 OAP57873.1 - 1.1e-06 27.9 0.1 1.5e-06 27.4 0.1 1.1 1 0 0 1 1 1 1 Carboxylesterase family PD40 PF07676.12 OAP57873.1 - 1.1e-06 28.4 1.9 0.022 14.7 0.1 2.6 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat BAAT_C PF08840.11 OAP57873.1 - 3.6e-06 27.1 0.1 6.6e-05 22.9 0.1 2.2 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_3 PF07859.13 OAP57873.1 - 1.9e-05 24.6 0.2 0.0003 20.7 0.2 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold AXE1 PF05448.12 OAP57873.1 - 0.00012 20.9 0.0 0.00026 19.8 0.0 1.5 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.16 OAP57873.1 - 0.0025 17.6 0.0 1.7 8.4 0.0 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 OAP57873.1 - 0.0037 17.9 1.0 0.019 15.5 1.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family LIP PF03583.14 OAP57873.1 - 0.0087 15.4 2.4 0.35 10.1 2.0 2.2 2 0 0 2 2 2 1 Secretory lipase Esterase PF00756.20 OAP57873.1 - 0.021 14.5 0.6 0.065 12.9 0.6 1.7 1 1 0 1 1 1 0 Putative esterase Esterase_phd PF10503.9 OAP57873.1 - 0.03 13.8 4.5 0.13 11.7 4.5 2.1 1 1 0 1 1 1 0 Esterase PHB depolymerase FSH1 PF03959.13 OAP57873.1 - 0.045 13.4 0.0 0.14 11.8 0.0 1.8 1 1 0 1 1 1 0 Serine hydrolase (FSH1) DUF1749 PF08538.10 OAP57873.1 - 0.097 11.7 0.1 0.26 10.3 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1749) PAE PF03283.13 OAP57873.1 - 0.1 11.7 0.0 0.2 10.7 0.0 1.4 1 0 0 1 1 1 0 Pectinacetylesterase DPPIV_N PF00930.21 OAP57873.1 - 0.14 10.9 0.1 0.43 9.3 0.0 1.7 2 0 0 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region NCE101 PF11654.8 OAP57874.1 - 2.9e-08 33.3 0.0 3.5e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Non-classical export protein 1 GFA PF04828.14 OAP57875.1 - 8.7e-24 83.7 0.3 1.1e-23 83.3 0.3 1.1 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Mito_carr PF00153.27 OAP57876.1 - 1.6e-32 111.3 5.4 2e-14 53.3 0.5 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein CFIA_Pcf11 PF11526.8 OAP57877.1 - 8.6e-08 32.6 0.1 2.5e-07 31.1 0.1 1.8 1 0 0 1 1 1 1 Subunit of cleavage factor IA Pcf11 CTD_bind PF04818.13 OAP57877.1 - 1.5e-06 29.0 0.0 4.9e-06 27.3 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase II-binding domain. VHS PF00790.19 OAP57877.1 - 0.0048 16.8 0.0 0.0094 15.8 0.0 1.4 1 0 0 1 1 1 1 VHS domain zf-ISL3 PF14690.6 OAP57877.1 - 0.025 15.3 0.3 0.053 14.2 0.3 1.5 1 0 0 1 1 1 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-C2H2_11 PF16622.5 OAP57877.1 - 0.16 11.8 0.1 0.31 10.9 0.1 1.4 1 0 0 1 1 1 0 zinc-finger C2H2-type zf_UBZ PF18439.1 OAP57877.1 - 0.39 10.3 2.1 2 8.1 2.1 2.0 1 1 0 1 1 1 0 Ubiquitin-Binding Zinc Finger HOOK PF05622.12 OAP57879.1 - 3.8e-28 98.1 49.7 5e-26 91.1 31.4 3.1 2 2 0 2 2 2 2 HOOK protein CtsR_C PF17727.1 OAP57879.1 - 0.0037 17.3 7.0 0.79 9.9 0.2 3.2 3 0 0 3 3 3 2 CtsR C-terminal dimerization domain KxDL PF10241.9 OAP57879.1 - 0.012 15.8 0.5 0.012 15.8 0.5 5.6 4 2 1 5 5 5 0 Uncharacterized conserved protein KASH_CCD PF14662.6 OAP57879.1 - 0.012 15.4 12.1 0.012 15.4 12.1 4.3 2 1 2 4 4 4 0 Coiled-coil region of CCDC155 or KASH DUF3896 PF13035.6 OAP57879.1 - 0.73 10.0 4.0 1.3 9.2 0.3 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3896) DUF4736 PF15883.5 OAP57879.1 - 1.8 8.3 9.4 0.37 10.5 5.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4736) Lactamase_B_2 PF12706.7 OAP57881.1 - 0.0097 15.4 0.2 0.025 14.1 0.2 1.8 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 OAP57881.1 - 0.01 15.9 2.1 0.019 15.0 2.1 1.7 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.6 OAP57881.1 - 0.13 12.1 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain NAD_binding_2 PF03446.15 OAP57882.1 - 7.9e-31 107.4 1.0 1.4e-30 106.6 1.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 OAP57882.1 - 4.6e-20 72.1 0.0 3.1e-19 69.4 0.0 2.2 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase OCD_Mu_crystall PF02423.15 OAP57882.1 - 5.1e-05 22.4 0.0 9e-05 21.5 0.0 1.3 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family F420_oxidored PF03807.17 OAP57882.1 - 0.015 15.9 0.1 0.039 14.5 0.1 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 OAP57882.1 - 0.096 12.6 0.1 0.27 11.1 0.0 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Metallophos_2 PF12850.7 OAP57882.1 - 0.11 12.7 0.0 0.59 10.3 0.0 1.9 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase superfamily domain Fungal_trans PF04082.18 OAP57883.1 - 1.7e-13 50.2 0.7 8.4e-13 48.0 0.7 2.2 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 OAP57883.1 - 3.6e-07 30.3 12.7 0.0049 17.2 5.4 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OAP57883.1 - 2.4e-06 27.7 3.1 2.4e-06 27.7 3.1 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 OAP57883.1 - 5.2e-05 23.7 11.6 0.013 16.3 4.5 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OAP57883.1 - 0.23 11.8 4.1 0.87 9.9 1.5 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zinc_ribbon_4 PF13717.6 OAP57883.1 - 0.53 10.2 1.9 4.4 7.3 0.5 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_11 PF16622.5 OAP57883.1 - 2.4 8.0 7.9 7 6.5 0.1 2.6 2 0 0 2 2 2 0 zinc-finger C2H2-type Lactamase_B PF00753.27 OAP57884.1 - 1.4e-11 44.8 2.0 5.9e-11 42.7 2.0 1.9 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OAP57884.1 - 0.012 15.2 0.8 0.042 13.4 0.3 2.2 2 1 1 3 3 3 0 Beta-lactamase superfamily domain CMD PF02627.20 OAP57885.1 - 3e-14 52.8 0.0 9e-06 25.7 0.0 2.3 2 0 0 2 2 2 2 Carboxymuconolactone decarboxylase family MFS_1 PF07690.16 OAP57886.1 - 2.5e-38 131.9 21.6 3.6e-38 131.4 21.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 OAP57886.1 - 0.31 9.3 8.3 0.61 8.3 5.1 2.6 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Alpha-amylase PF00128.24 OAP57887.1 - 4.2e-22 79.1 0.2 1.1e-21 77.8 0.2 1.6 1 1 0 1 1 1 1 Alpha amylase, catalytic domain DUF1939 PF09154.10 OAP57887.1 - 0.0096 16.1 0.1 0.024 14.8 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1939) Glyco_hydro_70 PF02324.16 OAP57887.1 - 0.025 12.8 0.0 2.3 6.3 0.0 2.6 3 0 0 3 3 3 0 Glycosyl hydrolase family 70 Tannase PF07519.11 OAP57888.1 - 4.8e-99 332.4 1.7 5.6e-99 332.2 1.7 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.21 OAP57888.1 - 0.00037 20.0 0.1 0.045 13.2 0.1 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 OAP57888.1 - 0.00074 18.8 0.0 0.0034 16.7 0.0 2.0 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OAP57888.1 - 0.036 13.7 0.0 0.091 12.4 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold ADK PF00406.22 OAP57889.1 - 1.8e-59 200.2 0.0 2.4e-59 199.8 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 OAP57889.1 - 2e-21 76.8 0.3 5.3e-21 75.5 0.0 1.7 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 OAP57889.1 - 2.7e-17 62.4 0.0 5.5e-17 61.5 0.0 1.5 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 OAP57889.1 - 9e-05 23.0 0.0 0.00017 22.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 OAP57889.1 - 0.00057 20.1 0.0 0.00097 19.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain GFO_IDH_MocA PF01408.22 OAP57890.1 - 7.8e-14 52.5 0.0 1.4e-13 51.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold RRM_1 PF00076.22 OAP57891.1 - 3.6e-17 62.0 0.0 2.5e-13 49.6 0.0 3.0 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.15 OAP57891.1 - 0.17 11.9 0.0 0.46 10.5 0.0 1.7 2 0 0 2 2 2 0 DbpA RNA binding domain GST_N_3 PF13417.6 OAP57892.1 - 1.6e-14 54.0 0.0 3e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 OAP57892.1 - 2e-12 47.3 0.0 3.5e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OAP57892.1 - 1.9e-09 37.7 0.0 3.6e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OAP57892.1 - 6.4e-09 35.9 0.1 1.4e-08 34.8 0.1 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OAP57892.1 - 7.6e-07 29.1 0.1 3.4e-06 27.0 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OAP57892.1 - 0.00012 22.2 0.0 0.00019 21.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 OAP57892.1 - 0.01 15.6 0.0 0.02 14.7 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 OAP57892.1 - 0.17 12.6 0.0 0.29 11.9 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain Methyltransf_11 PF08241.12 OAP57894.1 - 6e-17 62.1 0.1 1e-16 61.4 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAP57894.1 - 1.4e-16 61.0 0.0 2.2e-16 60.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAP57894.1 - 9.5e-15 55.2 0.0 1.6e-14 54.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAP57894.1 - 1.3e-12 47.8 0.0 1.7e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAP57894.1 - 3.6e-11 43.2 0.0 5e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 OAP57894.1 - 4.7e-11 42.5 0.0 6.4e-11 42.1 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 OAP57894.1 - 1.2e-07 31.3 0.0 1.8e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_33 PF10017.9 OAP57894.1 - 9.2e-06 25.0 0.0 8.5e-05 21.9 0.0 2.0 2 0 0 2 2 2 1 Histidine-specific methyltransferase, SAM-dependent PrmA PF06325.13 OAP57894.1 - 1.1e-05 25.1 0.0 1.6e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.19 OAP57894.1 - 2.6e-05 24.1 0.0 3.7e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 OAP57894.1 - 2.7e-05 23.8 0.0 8e-05 22.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_5 PF01795.19 OAP57894.1 - 0.00016 21.3 0.0 0.0025 17.4 0.0 2.0 1 1 1 2 2 2 1 MraW methylase family Methyltransf_2 PF00891.18 OAP57894.1 - 0.00044 19.6 0.0 0.0005 19.4 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_32 PF13679.6 OAP57894.1 - 0.00075 19.5 0.0 0.001 19.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 OAP57894.1 - 0.00076 19.4 0.0 0.0013 18.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 OAP57894.1 - 0.0024 16.8 0.0 0.0036 16.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_8 PF05148.15 OAP57894.1 - 0.0051 16.7 0.1 0.083 12.7 0.1 2.1 1 1 0 1 1 1 1 Hypothetical methyltransferase FtsJ PF01728.19 OAP57894.1 - 0.014 15.5 0.0 0.069 13.2 0.0 2.0 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_20 PF12147.8 OAP57894.1 - 0.028 13.6 0.0 0.033 13.3 0.0 1.1 1 0 0 1 1 1 0 Putative methyltransferase TehB PF03848.14 OAP57894.1 - 0.15 11.4 0.0 0.35 10.3 0.0 1.6 1 1 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_7 PF03492.15 OAP57894.1 - 0.2 10.8 0.1 0.53 9.4 0.0 1.7 2 0 0 2 2 2 0 SAM dependent carboxyl methyltransferase CDC14 PF08045.11 OAP57895.1 - 3.4e-117 390.6 0.0 4.1e-117 390.3 0.0 1.0 1 0 0 1 1 1 1 Cell division control protein 14, SIN component polyprenyl_synt PF00348.17 OAP57896.1 - 5.6e-66 222.2 0.0 6.8e-66 221.9 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Translin PF01997.16 OAP57896.1 - 0.015 15.3 0.0 0.034 14.1 0.0 1.6 1 1 0 1 1 1 0 Translin family p450 PF00067.22 OAP57897.1 - 1.1e-61 209.0 0.0 1.5e-61 208.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 IGPS PF00218.21 OAP57898.1 - 6.8e-96 320.3 0.0 1.4e-95 319.3 0.0 1.5 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase GATase PF00117.28 OAP57898.1 - 1.6e-45 155.3 0.0 3.1e-45 154.3 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I PRAI PF00697.22 OAP57898.1 - 2.4e-45 154.7 0.1 1.6e-39 135.7 0.0 2.6 2 1 1 3 3 3 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase QRPTase_C PF01729.19 OAP57898.1 - 1.4e-05 25.0 0.2 0.00052 19.8 0.0 2.7 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, C-terminal domain Peptidase_C26 PF07722.13 OAP57898.1 - 7.4e-05 22.6 0.5 0.00031 20.6 0.5 1.9 1 1 0 1 1 1 1 Peptidase C26 NanE PF04131.14 OAP57898.1 - 0.0042 16.3 0.2 0.063 12.5 0.0 2.5 2 0 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase Peripla_BP_2 PF01497.18 OAP57898.1 - 0.012 15.2 0.0 0.036 13.6 0.0 1.7 2 0 0 2 2 2 0 Periplasmic binding protein His_biosynth PF00977.21 OAP57898.1 - 0.027 14.0 0.2 0.63 9.5 0.0 3.0 4 0 0 4 4 4 0 Histidine biosynthesis protein PdxJ PF03740.13 OAP57898.1 - 0.038 13.1 0.0 9 5.3 0.0 2.8 1 1 0 2 2 2 0 Pyridoxal phosphate biosynthesis protein PdxJ FMN_dh PF01070.18 OAP57898.1 - 0.2 10.6 0.6 13 4.7 0.1 2.4 2 0 0 2 2 2 0 FMN-dependent dehydrogenase AhpC-TSA_2 PF13911.6 OAP57899.1 - 7.2e-13 48.7 0.0 1.5e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme UPF1_Zn_bind PF09416.10 OAP57900.1 - 1.9e-72 242.2 3.8 2.3e-72 242.0 2.2 1.9 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.6 OAP57900.1 - 3.9e-60 202.9 0.0 8.5e-60 201.8 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 OAP57900.1 - 2.3e-54 185.0 2.5 6.8e-31 108.0 0.2 2.4 1 1 1 2 2 2 2 AAA domain DUF5599 PF18141.1 OAP57900.1 - 2e-33 114.5 0.0 3.8e-33 113.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5599) AAA_30 PF13604.6 OAP57900.1 - 2.6e-13 50.1 0.2 3e-12 46.7 0.2 2.4 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OAP57900.1 - 4.4e-11 43.3 0.0 2.6e-10 40.8 0.0 2.3 2 1 0 2 2 2 1 AAA domain ResIII PF04851.15 OAP57900.1 - 5.7e-06 26.4 0.0 1.1e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 OAP57900.1 - 0.00022 21.0 0.1 0.6 9.8 0.0 2.8 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 OAP57900.1 - 0.00058 19.2 0.2 0.0089 15.3 0.0 2.4 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.14 OAP57900.1 - 0.0012 18.8 0.0 0.0024 17.7 0.0 1.6 1 0 0 1 1 1 1 Helicase UvrD-helicase PF00580.21 OAP57900.1 - 0.0017 17.9 0.1 0.043 13.3 0.0 2.5 2 1 1 3 3 3 1 UvrD/REP helicase N-terminal domain PIF1 PF05970.14 OAP57900.1 - 0.0022 17.2 0.1 0.56 9.3 0.0 2.2 2 0 0 2 2 2 2 PIF1-like helicase DEAD PF00270.29 OAP57900.1 - 0.006 16.4 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_10 PF12846.7 OAP57900.1 - 0.033 13.1 0.0 0.051 12.5 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain Ribosomal_S13_N PF08069.12 OAP57900.1 - 0.074 13.1 0.0 0.2 11.7 0.0 1.7 1 0 0 1 1 1 0 Ribosomal S13/S15 N-terminal domain AAA_22 PF13401.6 OAP57900.1 - 0.12 12.6 0.0 0.38 11.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 OAP57900.1 - 0.15 11.4 0.0 0.44 9.9 0.0 1.8 2 0 0 2 2 2 0 KaiC zf-UBP PF02148.19 OAP57900.1 - 1.7 9.1 7.0 4.3 7.7 7.0 1.7 1 0 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein Brix PF04427.18 OAP57901.1 - 2.4e-29 102.8 0.0 3e-29 102.5 0.0 1.1 1 0 0 1 1 1 1 Brix domain Nup188_C PF18378.1 OAP57903.1 - 9.7e-71 238.5 0.3 3e-70 236.9 0.3 1.9 1 1 0 1 1 1 1 Nuclear pore protein NUP188 C-terminal domain Nup188 PF10487.9 OAP57903.1 - 3e-55 187.6 0.1 2.5e-53 181.3 0.1 2.6 1 1 0 1 1 1 1 Nucleoporin subcomplex protein binding to Pom34 AMP-binding PF00501.28 OAP57905.1 - 8.3e-85 284.9 0.0 1.1e-84 284.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAP57905.1 - 1.4e-15 58.1 0.1 3.9e-15 56.6 0.1 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF4188 PF13826.6 OAP57906.1 - 1e-31 109.7 0.8 1.7e-31 109.0 0.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4188) DUF3291 PF11695.8 OAP57906.1 - 0.00042 20.0 0.2 0.00061 19.5 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3291) Dehydratase_hem PF13816.6 OAP57906.1 - 0.0053 16.2 2.2 0.016 14.6 2.2 1.6 1 1 0 1 1 1 1 Haem-containing dehydratase FAM86 PF14904.6 OAP57906.1 - 0.056 13.5 0.0 0.87 9.7 0.0 2.1 2 0 0 2 2 2 0 Family of unknown function FA_desaturase PF00487.24 OAP57907.1 - 1.7e-24 87.0 18.6 3.6e-24 86.0 18.6 1.4 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 OAP57907.1 - 3.3e-07 30.6 0.0 2.8e-06 27.6 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3474) TRAPPC10 PF12584.8 OAP57908.1 - 9.9e-14 51.3 0.0 2.2e-13 50.2 0.0 1.6 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 RVT_1 PF00078.27 OAP57909.1 - 0.0069 15.9 0.0 0.018 14.6 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SWIM PF04434.17 OAP57910.1 - 8.9e-05 22.1 1.1 0.15 11.8 0.0 2.4 2 0 0 2 2 2 2 SWIM zinc finger MitMem_reg PF13012.6 OAP57911.1 - 5.1e-38 129.9 0.2 8.6e-38 129.2 0.2 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 OAP57911.1 - 2.7e-31 108.0 0.6 1.4e-30 105.7 0.0 2.1 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF1682 PF07946.14 OAP57911.1 - 0.025 13.8 2.3 0.034 13.4 2.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Connexin PF00029.19 OAP57911.1 - 0.036 13.8 1.2 0.063 13.0 1.2 1.3 1 0 0 1 1 1 0 Connexin DUF2999 PF11212.8 OAP57911.1 - 0.058 13.7 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2999) FAM176 PF14851.6 OAP57911.1 - 0.31 10.7 2.0 0.69 9.6 2.0 1.5 1 0 0 1 1 1 0 FAM176 family NARP1 PF12569.8 OAP57911.1 - 2.8 6.7 9.4 3.8 6.3 9.4 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 ALMT PF11744.8 OAP57911.1 - 5.8 5.6 5.7 8.4 5.1 5.7 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter p450 PF00067.22 OAP57912.1 - 7.5e-71 239.2 0.0 9e-71 239.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ThuA PF06283.11 OAP57912.1 - 0.073 13.3 0.8 1.9 8.7 0.0 2.5 3 0 0 3 3 3 0 Trehalose utilisation Cu-oxidase_2 PF07731.14 OAP57913.1 - 2.4e-37 127.7 7.4 1.5e-35 121.9 0.6 3.2 2 2 1 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 OAP57913.1 - 6.4e-36 123.0 2.6 6.4e-36 123.0 2.6 3.4 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase PF00394.22 OAP57913.1 - 1.5e-27 96.6 0.1 1.5e-27 96.6 0.1 2.8 3 1 0 3 3 3 1 Multicopper oxidase Keratin_2_head PF16208.5 OAP57914.1 - 0.25 11.5 12.7 0.46 10.6 12.7 1.3 1 0 0 1 1 1 0 Keratin type II head DUF5320 PF17253.2 OAP57914.1 - 1.2 10.2 5.5 0.33 12.0 1.5 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5320) Fungal_trans PF04082.18 OAP57915.1 - 9.4e-10 38.0 0.0 1.6e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain TRI12 PF06609.13 OAP57916.1 - 5e-44 150.7 17.2 6e-44 150.5 17.2 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAP57916.1 - 1.4e-18 67.0 53.7 3.4e-18 65.7 51.5 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAP57916.1 - 5.2e-06 25.6 17.7 5.2e-06 25.6 17.7 3.3 3 2 0 3 3 3 1 Sugar (and other) transporter Cupin_2 PF07883.11 OAP57917.1 - 3.6e-08 33.0 0.1 6.1e-08 32.3 0.1 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.7 OAP57917.1 - 0.00016 21.4 0.4 0.0003 20.5 0.4 1.4 2 0 0 2 2 2 1 Cupin AraC_binding PF02311.19 OAP57917.1 - 0.0023 17.9 0.3 0.0029 17.5 0.3 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain BppL_N PF18338.1 OAP57917.1 - 0.018 14.8 1.7 0.12 12.2 1.7 2.2 1 1 0 1 1 1 0 Lower baseplate protein N-terminal domain Cupin_3 PF05899.12 OAP57917.1 - 0.056 13.1 0.0 0.14 11.8 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF861) Cupin_2 PF07883.11 OAP57918.1 - 0.0012 18.5 0.1 0.005 16.5 0.1 2.0 2 0 0 2 2 2 1 Cupin domain Ectoine_synth PF06339.12 OAP57918.1 - 0.021 15.0 0.0 0.037 14.2 0.0 1.4 1 0 0 1 1 1 0 Ectoine synthase adh_short PF00106.25 OAP57919.1 - 2.1e-44 151.3 0.0 2.5e-44 151.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP57919.1 - 1.7e-31 109.6 0.0 2.2e-31 109.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP57919.1 - 5.7e-08 32.9 0.0 8.2e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAP57919.1 - 1.3e-05 24.8 0.0 3.7e-05 23.3 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 OAP57919.1 - 0.0026 17.7 0.0 0.0031 17.4 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 OAP57919.1 - 0.0031 17.1 0.1 0.026 14.1 0.0 2.0 2 0 0 2 2 2 1 NmrA-like family F420_oxidored PF03807.17 OAP57919.1 - 0.023 15.3 0.0 0.044 14.4 0.0 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent RmlD_sub_bind PF04321.17 OAP57919.1 - 0.061 12.4 0.0 0.16 11.0 0.0 1.7 1 1 0 1 1 1 0 RmlD substrate binding domain NAD_binding_2 PF03446.15 OAP57919.1 - 0.065 13.4 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase TRI12 PF06609.13 OAP57920.1 - 1.5e-51 175.5 14.9 2e-51 175.2 14.9 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAP57920.1 - 1.8e-14 53.5 49.7 6.4e-12 45.1 47.8 3.2 2 1 0 2 2 2 1 Major Facilitator Superfamily Cupin_2 PF07883.11 OAP57921.1 - 8.1e-09 35.1 0.1 1.8e-08 33.9 0.1 1.6 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 OAP57921.1 - 5.6e-06 26.3 0.2 7.4e-06 25.9 0.2 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.22 OAP57921.1 - 0.0012 18.5 0.0 0.0016 18.0 0.0 1.2 1 1 0 1 1 1 1 Cupin Cupin_6 PF12852.7 OAP57921.1 - 0.0054 16.5 0.1 0.0089 15.8 0.0 1.4 1 1 0 1 1 1 1 Cupin Cupin_3 PF05899.12 OAP57921.1 - 0.017 14.8 0.4 0.051 13.3 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF861) ADH_N PF08240.12 OAP57922.1 - 5.9e-29 100.1 1.1 1.1e-28 99.3 1.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAP57922.1 - 7.5e-16 58.3 0.2 1.5e-15 57.3 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAP57922.1 - 6.9e-06 27.2 0.0 2.8e-05 25.2 0.0 1.9 1 1 1 2 2 2 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 OAP57922.1 - 0.00016 21.2 0.0 0.00036 20.1 0.0 1.5 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 OAP57922.1 - 0.0007 19.0 0.9 0.0014 18.0 0.9 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Lactamase_B PF00753.27 OAP57923.1 - 2.5e-09 37.4 0.3 6.8e-09 36.0 0.3 1.7 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OAP57923.1 - 0.022 14.3 0.0 0.038 13.5 0.0 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Fungal_trans PF04082.18 OAP57924.1 - 1.6e-13 50.3 0.2 2.8e-13 49.5 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain CMD PF02627.20 OAP57925.1 - 1.9e-20 72.7 0.6 2.6e-20 72.3 0.6 1.2 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family adh_short PF00106.25 OAP57926.1 - 1.7e-31 109.2 0.0 2.3e-31 108.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP57926.1 - 3.9e-21 75.7 0.0 5.2e-21 75.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP57926.1 - 1.7e-07 31.3 0.3 1.1e-05 25.5 0.3 2.9 1 1 0 1 1 1 1 KR domain FMO-like PF00743.19 OAP57927.1 - 9.9e-18 63.8 2.3 5.8e-16 58.0 2.3 2.8 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 OAP57927.1 - 2e-10 40.4 0.0 4.2e-08 32.8 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAP57927.1 - 2e-07 31.1 0.1 8.5e-07 29.1 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 OAP57927.1 - 3.1e-06 26.7 1.4 0.005 16.1 0.0 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAP57927.1 - 5e-06 25.9 0.1 6.6e-05 22.2 0.0 2.5 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) DUF3738 PF12543.8 OAP57927.1 - 0.034 14.3 0.0 0.053 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3738) Flavodoxin_1 PF00258.25 OAP57927.1 - 0.072 13.3 0.0 0.19 11.9 0.0 1.8 1 0 0 1 1 1 0 Flavodoxin NAD_binding_9 PF13454.6 OAP57927.1 - 0.089 12.8 0.0 15 5.6 0.0 3.1 3 0 0 3 3 3 0 FAD-NAD(P)-binding ARL2_Bind_BART PF11527.8 OAP57927.1 - 0.13 12.4 0.2 0.26 11.4 0.2 1.4 1 0 0 1 1 1 0 The ARF-like 2 binding protein BART 2-Hacid_dh_C PF02826.19 OAP57927.1 - 0.21 10.9 0.1 5 6.5 0.0 2.3 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Abhydrolase_3 PF07859.13 OAP57928.1 - 3.8e-45 154.3 0.1 9.9e-45 153.0 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold COesterase PF00135.28 OAP57928.1 - 2.1e-12 46.7 0.1 4.4e-12 45.7 0.1 1.5 1 1 0 1 1 1 1 Carboxylesterase family Esterase_phd PF10503.9 OAP57928.1 - 0.059 12.9 0.1 0.099 12.1 0.1 1.4 1 0 0 1 1 1 0 Esterase PHB depolymerase Say1_Mug180 PF10340.9 OAP57928.1 - 0.065 12.1 0.0 0.087 11.7 0.0 1.1 1 0 0 1 1 1 0 Steryl acetyl hydrolase DUF498 PF04430.14 OAP57928.1 - 0.065 13.3 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF498/DUF598) Abhydrolase_6 PF12697.7 OAP57928.1 - 0.25 11.9 3.5 0.27 11.8 2.5 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family FMO-like PF00743.19 OAP57929.1 - 2.6e-13 49.3 0.5 1.1e-12 47.2 0.2 2.0 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OAP57929.1 - 9.1e-12 45.0 0.0 1.8e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 OAP57929.1 - 1.9e-06 27.3 0.0 0.0034 16.6 0.0 3.7 2 1 2 4 4 4 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 OAP57929.1 - 8e-05 22.0 0.0 0.0067 15.7 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAP57929.1 - 0.00021 21.3 0.0 0.013 15.4 0.0 2.9 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 OAP57929.1 - 0.0039 16.5 0.0 0.083 12.1 0.0 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAP57929.1 - 0.0041 16.7 0.0 0.91 9.0 0.0 3.0 3 0 0 3 3 3 1 FAD dependent oxidoreductase PS_pyruv_trans PF04230.13 OAP57929.1 - 0.008 16.1 0.7 0.069 13.1 0.2 2.5 3 0 0 3 3 3 1 Polysaccharide pyruvyl transferase ARL2_Bind_BART PF11527.8 OAP57929.1 - 0.017 15.2 1.2 1.2 9.2 0.3 2.4 2 0 0 2 2 2 0 The ARF-like 2 binding protein BART APP_N PF02177.16 OAP57929.1 - 0.035 14.5 0.2 2.1 8.8 0.0 2.3 2 0 0 2 2 2 0 Amyloid A4 N-terminal heparin-binding Shikimate_DH PF01488.20 OAP57929.1 - 0.11 12.5 0.0 17 5.5 0.0 3.0 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.17 OAP57929.1 - 0.13 11.4 0.0 0.78 8.9 0.0 2.1 3 0 0 3 3 3 0 Thi4 family adh_short_C2 PF13561.6 OAP57930.1 - 1.1e-63 214.9 0.1 1.3e-63 214.7 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP57930.1 - 6.4e-48 162.8 0.1 8.1e-48 162.5 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAP57930.1 - 1.4e-08 34.9 1.3 2.1e-08 34.3 1.3 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 OAP57930.1 - 0.015 15.2 0.1 0.022 14.7 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DNA_pol_B_exo2 PF10108.9 OAP57930.1 - 0.12 12.1 0.0 0.23 11.1 0.0 1.4 2 0 0 2 2 2 0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB IreB PF06135.12 OAP57930.1 - 0.16 12.2 0.0 0.71 10.1 0.0 1.9 2 0 0 2 2 2 0 IreB regulatory phosphoprotein NmrA PF05368.13 OAP57930.1 - 0.19 11.2 0.1 0.76 9.3 0.1 1.9 2 1 1 3 3 3 0 NmrA-like family Cyclase PF04199.13 OAP57931.1 - 7.2e-16 58.7 0.0 1.1e-15 58.0 0.0 1.3 1 0 0 1 1 1 1 Putative cyclase DUF5490 PF17593.2 OAP57931.1 - 0.076 13.0 0.1 0.18 11.8 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5490) adh_short_C2 PF13561.6 OAP57932.1 - 5e-58 196.4 0.0 7e-58 195.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP57932.1 - 5.3e-42 143.5 0.0 6.9e-42 143.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAP57932.1 - 4.9e-14 52.6 0.0 7.3e-14 52.1 0.0 1.2 1 0 0 1 1 1 1 KR domain HATPase_c PF02518.26 OAP57932.1 - 0.043 14.3 0.0 0.14 12.7 0.0 1.8 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 2-Hacid_dh_C PF02826.19 OAP57932.1 - 0.17 11.2 0.1 0.37 10.1 0.1 1.5 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain adh_short_C2 PF13561.6 OAP57933.1 - 2.5e-54 184.3 0.0 3.1e-54 184.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP57933.1 - 5.8e-45 153.2 0.1 7.2e-45 152.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAP57933.1 - 1.7e-09 37.8 0.0 2.5e-09 37.3 0.0 1.1 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.17 OAP57933.1 - 0.051 14.1 0.3 0.099 13.2 0.3 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 OAP57933.1 - 0.3 11.0 1.1 0.46 10.3 1.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Fungal_trans PF04082.18 OAP57934.1 - 2.3e-11 43.3 0.1 3.9e-11 42.5 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain SGL PF08450.12 OAP57935.1 - 1.9e-11 44.0 0.1 1.1e-10 41.5 0.1 2.0 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 OAP57935.1 - 0.0017 18.3 0.0 0.68 10.1 0.0 3.1 2 0 0 2 2 2 2 NHL repeat Arylesterase PF01731.20 OAP57935.1 - 0.085 13.1 0.1 0.58 10.4 0.0 2.3 2 0 0 2 2 2 0 Arylesterase DUF1869 PF08956.10 OAP57935.1 - 0.095 12.6 0.2 4.1 7.4 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1869) NAD_binding_2 PF03446.15 OAP57936.1 - 8.2e-24 84.6 0.5 1.3e-23 84.0 0.2 1.4 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 OAP57936.1 - 1.4e-19 70.6 0.0 2.1e-19 70.0 0.0 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Sugar_tr PF00083.24 OAP57937.1 - 5e-87 292.6 20.6 5.7e-87 292.5 20.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP57937.1 - 6e-25 87.9 34.4 6.4e-15 54.9 10.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 OAP57937.1 - 0.057 12.3 18.5 0.0061 15.5 2.7 3.6 3 1 1 4 4 4 0 MFS_1 like family Sugar_tr PF00083.24 OAP57938.1 - 3.2e-77 260.3 22.4 3.8e-77 260.1 22.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP57938.1 - 7.6e-17 61.3 29.2 7.6e-17 61.3 29.2 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF3302 PF11742.8 OAP57938.1 - 0.1 12.7 2.2 0.43 10.7 2.2 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3302) NAD_binding_2 PF03446.15 OAP57939.1 - 6.5e-29 101.1 0.1 1e-28 100.5 0.1 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 OAP57939.1 - 5.8e-22 78.2 0.0 1.1e-21 77.4 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase OCD_Mu_crystall PF02423.15 OAP57939.1 - 0.065 12.2 0.0 0.11 11.4 0.0 1.4 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family Beta-lactamase PF00144.24 OAP57940.1 - 9.4e-37 127.0 0.0 6.5e-36 124.2 0.0 1.9 1 1 0 1 1 1 1 Beta-lactamase MAT1-1-2 PF17043.5 OAP57940.1 - 0.15 11.9 0.1 3.8 7.4 0.0 2.2 2 0 0 2 2 2 0 Mating type protein 1-1-2 of unknown function SesA PF17107.5 OAP57941.1 - 6.7e-20 71.5 2.0 8.5e-20 71.2 2.0 1.1 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases YqfQ PF14181.6 OAP57941.1 - 0.014 15.6 0.2 0.017 15.4 0.2 1.1 1 0 0 1 1 1 0 YqfQ-like protein IQ_SEC7_PH PF16453.5 OAP57941.1 - 0.19 11.7 1.4 0.28 11.1 0.8 1.5 1 1 1 2 2 2 0 PH domain DUF1661 PF07877.11 OAP57941.1 - 0.26 11.0 0.1 0.26 11.0 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1661) DIOX_N PF14226.6 OAP57943.1 - 1.1e-14 55.2 0.0 2.4e-14 54.1 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OAP57943.1 - 1.8e-11 44.4 0.0 3.1e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Abhydrolase_6 PF12697.7 OAP57945.1 - 8.4e-14 52.7 0.4 1.3e-13 52.1 0.4 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAP57945.1 - 1.9e-10 40.8 0.0 7.6e-09 35.6 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 OAP57945.1 - 0.021 13.7 0.0 0.034 13.1 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme CsoSCA PF08936.10 OAP57945.1 - 0.11 11.1 0.0 0.16 10.6 0.0 1.1 1 0 0 1 1 1 0 Carboxysome Shell Carbonic Anhydrase Gyro_capsid PF04162.12 OAP57946.1 - 0.054 12.0 1.9 0.1 11.1 1.9 1.4 1 0 0 1 1 1 0 Gyrovirus capsid protein (VP1) CLN3 PF02487.17 OAP57947.1 - 1.2e-160 535.0 4.8 1.4e-160 534.8 4.8 1.0 1 0 0 1 1 1 1 CLN3 protein Rxt3 PF08642.10 OAP57948.1 - 3.8e-28 98.8 0.0 6.8e-27 94.7 0.0 2.7 1 1 0 1 1 1 1 Histone deacetylation protein Rxt3 LCCL PF03815.19 OAP57948.1 - 0.00028 20.9 0.0 0.0019 18.3 0.0 2.1 1 1 0 1 1 1 1 LCCL domain DUF1992 PF09350.10 OAP57949.1 - 4e-21 74.9 0.1 1.1e-20 73.6 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1992) RPAP1_N PF08621.10 OAP57949.1 - 0.075 12.8 0.6 0.19 11.5 0.0 2.0 2 0 0 2 2 2 0 RPAP1-like, N-terminal DTHCT PF08070.11 OAP57951.1 - 0.55 11.0 12.7 0.09 13.5 7.8 2.1 2 0 0 2 2 2 0 DTHCT (NUC029) region MFS_1 PF07690.16 OAP57952.1 - 9.1e-27 93.9 43.8 1.3e-26 93.4 43.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4338 PF14236.6 OAP57952.1 - 0.12 11.6 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4338) SecD_SecF PF02355.16 OAP57952.1 - 0.16 11.3 2.5 0.5 9.7 1.4 2.2 2 0 0 2 2 2 0 Protein export membrane protein HMGL-like PF00682.19 OAP57953.1 - 1.1e-42 146.5 0.0 2e-31 109.5 0.1 2.0 2 0 0 2 2 2 2 HMGL-like LCM PF04072.14 OAP57955.1 - 1.6e-14 54.3 0.0 6.5e-14 52.3 0.0 1.8 2 0 0 2 2 2 1 Leucine carboxyl methyltransferase Cupin_8 PF13621.6 OAP57955.1 - 5.6e-10 39.4 0.0 1.1e-09 38.4 0.0 1.4 1 0 0 1 1 1 1 Cupin-like domain Kelch_4 PF13418.6 OAP57955.1 - 6.1e-08 32.5 1.0 0.0011 19.0 0.0 3.8 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_5 PF13854.6 OAP57955.1 - 0.07 13.1 0.8 14 5.8 0.0 3.5 3 0 0 3 3 3 0 Kelch motif Haem_oxygenas_2 PF14518.6 OAP57955.1 - 0.096 12.5 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Iron-containing redox enzyme L51_S25_CI-B8 PF05047.16 OAP57959.1 - 1.9e-06 27.7 0.0 4.7e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain APOBEC4 PF18775.1 OAP57959.1 - 0.18 12.0 0.0 0.35 11.0 0.0 1.4 1 0 0 1 1 1 0 APOBEC4 Ctr PF04145.15 OAP57960.1 - 6.2e-30 104.8 0.2 8.1e-30 104.4 0.2 1.1 1 0 0 1 1 1 1 Ctr copper transporter family FA_hydroxylase PF04116.13 OAP57961.1 - 0.022 15.1 0.3 0.029 14.7 0.3 1.1 1 0 0 1 1 1 0 Fatty acid hydroxylase superfamily NAD_binding_4 PF07993.12 OAP57962.1 - 0.001 18.3 0.0 0.0016 17.6 0.0 1.3 1 1 0 1 1 1 1 Male sterility protein Acyl_transf_3 PF01757.22 OAP57963.1 - 3.6e-33 115.1 23.4 6.3e-33 114.3 23.4 1.4 1 0 0 1 1 1 1 Acyltransferase family SLC35F PF06027.12 OAP57964.1 - 2.3e-98 329.4 22.8 2.7e-98 329.2 22.8 1.0 1 0 0 1 1 1 1 Solute carrier family 35 CRT-like PF08627.10 OAP57964.1 - 8.2e-12 44.7 1.8 1.4e-11 44.0 1.8 1.3 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 OAP57964.1 - 0.013 15.7 33.0 0.015 15.4 15.0 2.3 2 0 0 2 2 2 0 EamA-like transporter family ExoD PF06055.12 OAP57964.1 - 2.9 7.2 8.2 0.37 10.2 0.5 2.7 3 0 0 3 3 3 0 Exopolysaccharide synthesis, ExoD HCV_env PF01539.17 OAP57964.1 - 8.4 6.0 11.3 0.066 12.9 2.3 2.0 2 1 1 3 3 3 0 Hepatitis C virus envelope glycoprotein E1 DUF2207 PF09972.9 OAP57964.1 - 8.9 4.9 13.6 1.9 7.1 3.2 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Ribosomal_L7Ae PF01248.26 OAP57965.1 - 2.6e-25 88.0 1.1 5.9e-25 86.8 1.1 1.6 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Ank_2 PF12796.7 OAP57965.1 - 8.8e-25 87.1 0.0 2.1e-09 37.8 0.0 3.6 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OAP57965.1 - 1.4e-21 76.2 0.7 1.2e-08 35.1 0.1 5.6 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 OAP57965.1 - 6.8e-21 74.4 0.0 2.7e-08 34.2 0.0 4.3 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAP57965.1 - 4.7e-15 54.2 1.3 0.00035 20.8 0.0 5.9 6 0 0 6 6 6 3 Ankyrin repeat Ank PF00023.30 OAP57965.1 - 2.8e-12 46.5 0.1 0.0069 16.8 0.0 5.0 5 0 0 5 5 5 3 Ankyrin repeat Steroid_dh PF02544.16 OAP57966.1 - 4.7e-07 29.9 0.7 0.00073 19.5 0.1 2.6 2 0 0 2 2 2 2 3-oxo-5-alpha-steroid 4-dehydrogenase BCS1_N PF08740.11 OAP57967.1 - 7e-28 97.9 0.0 1.5e-27 96.8 0.0 1.5 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 OAP57967.1 - 1.3e-15 58.0 0.0 1e-06 29.2 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 OAP57967.1 - 0.0007 19.5 0.7 0.43 10.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.12 OAP57967.1 - 0.0009 19.0 0.0 0.0017 18.1 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 OAP57967.1 - 0.0013 19.1 0.0 0.01 16.3 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 OAP57967.1 - 0.0034 17.4 0.0 0.013 15.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 OAP57967.1 - 0.031 14.0 0.0 0.056 13.2 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_7 PF12775.7 OAP57967.1 - 0.074 12.6 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_18 PF13238.6 OAP57967.1 - 0.081 13.5 0.0 0.081 13.5 0.0 2.8 2 1 0 2 2 1 0 AAA domain ParA PF10609.9 OAP57967.1 - 0.082 12.3 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase AAA_33 PF13671.6 OAP57967.1 - 0.23 11.6 0.0 0.23 11.6 0.0 2.2 2 0 0 2 2 1 0 AAA domain Scs3p PF10261.9 OAP57968.1 - 2.5e-67 227.0 4.8 3.4e-67 226.5 4.8 1.2 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM Cytochrom_B561 PF03188.16 OAP57969.1 - 6.7e-08 32.8 10.5 1.3e-07 31.8 10.5 1.4 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 CDH-cyt PF16010.5 OAP57969.1 - 6.5e-05 22.7 0.0 0.00016 21.5 0.0 1.7 1 1 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase PepSY_TM PF03929.16 OAP57969.1 - 0.0068 16.1 2.9 0.017 14.8 2.9 1.8 1 1 0 1 1 1 1 PepSY-associated TM region KleE PF17394.2 OAP57969.1 - 0.049 13.8 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized KleE stable inheritance protein Tmemb_14 PF03647.13 OAP57969.1 - 0.17 12.6 6.4 0.075 13.8 3.5 2.0 2 0 0 2 2 2 0 Transmembrane proteins 14C Nitroreductase PF00881.24 OAP57970.1 - 3.1e-13 50.1 0.0 6.8e-13 49.0 0.0 1.5 1 1 0 1 1 1 1 Nitroreductase family BDV_P40 PF06407.11 OAP57970.1 - 0.16 11.0 0.0 0.23 10.5 0.0 1.1 1 0 0 1 1 1 0 Borna disease virus P40 protein p450 PF00067.22 OAP57971.1 - 8.2e-68 229.2 0.0 9.9e-68 229.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Stm1_N PF09598.10 OAP57972.1 - 1.4e-16 61.1 4.4 1.4e-16 61.1 4.4 3.4 3 1 0 3 3 3 1 Stm1 HABP4_PAI-RBP1 PF04774.15 OAP57972.1 - 7.5e-05 23.6 10.0 7.5e-05 23.6 10.0 2.8 2 1 1 3 3 3 1 Hyaluronan / mRNA binding family mIF3 PF14877.6 OAP57972.1 - 0.074 12.7 0.5 0.11 12.2 0.5 1.2 1 0 0 1 1 1 0 Mitochondrial translation initiation factor PNK3P PF08645.11 OAP57972.1 - 0.12 12.1 0.2 0.18 11.5 0.2 1.2 1 0 0 1 1 1 0 Polynucleotide kinase 3 phosphatase bZIP_1 PF00170.21 OAP57973.1 - 5.5e-06 26.4 6.7 9e-06 25.7 6.7 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 OAP57973.1 - 0.00094 19.2 7.4 0.0019 18.2 7.4 1.5 1 0 0 1 1 1 1 Basic region leucine zipper Vir_act_alpha_C PF10400.9 OAP57973.1 - 0.073 13.8 3.4 0.13 13.0 3.4 1.4 1 0 0 1 1 1 0 Virulence activator alpha C-term IATP PF04568.12 OAP57973.1 - 2.9 8.4 7.7 2.3 8.7 3.0 2.6 2 0 0 2 2 2 0 Mitochondrial ATPase inhibitor, IATP bZIP_Maf PF03131.17 OAP57973.1 - 6.4 7.4 11.4 0.99 10.0 7.3 1.7 2 0 0 2 2 2 0 bZIP Maf transcription factor Arrestin_C PF02752.22 OAP57974.1 - 9.2e-10 39.1 0.6 3.5e-08 34.0 0.3 2.4 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain adh_short_C2 PF13561.6 OAP57975.1 - 1.7e-42 145.6 0.0 2.1e-42 145.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP57975.1 - 4.8e-38 130.6 0.0 7.3e-38 130.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAP57975.1 - 3e-07 30.5 0.1 4.7e-07 29.9 0.1 1.4 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OAP57975.1 - 0.14 11.3 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Epimerase PF01370.21 OAP57975.1 - 0.18 11.3 0.1 0.68 9.3 0.1 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAP57975.1 - 0.21 11.0 0.0 5.8 6.2 0.0 2.2 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Glyoxalase_3 PF13468.6 OAP57976.1 - 2.7e-20 73.2 0.0 9.7e-20 71.4 0.0 1.9 2 1 0 2 2 2 1 Glyoxalase-like domain SMK-1 PF04802.15 OAP57977.1 - 1e-77 260.3 6.2 1.6e-77 259.7 6.2 1.3 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 MIP-T3 PF10243.9 OAP57977.1 - 0.13 12.3 0.3 0.48 10.4 0.1 2.2 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 CH-like domain RNA_pol_Rpb2_2 PF04561.14 OAP57977.1 - 0.3 10.7 4.1 14 5.2 0.2 3.1 3 1 0 4 4 4 0 RNA polymerase Rpb2, domain 2 MBOAT_2 PF13813.6 OAP57978.1 - 2e-17 63.2 0.6 2e-17 63.2 0.6 2.3 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family 2OG-FeII_Oxy_2 PF13532.6 OAP57979.1 - 6.9e-13 49.2 0.0 2e-11 44.5 0.0 2.0 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Polysacc_deac_1 PF01522.21 OAP57980.1 - 2.2e-16 59.9 0.0 4.5e-16 58.9 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 OAP57980.1 - 1.1e-06 28.4 0.1 2.6e-06 27.2 0.1 1.7 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) Peroxidase_2 PF01328.17 OAP57980.1 - 0.036 14.6 0.0 0.069 13.7 0.0 1.4 1 0 0 1 1 1 0 Peroxidase, family 2 DUF2194 PF09960.9 OAP57980.1 - 0.066 11.5 0.0 0.089 11.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2194) HeH PF12949.7 OAP57980.1 - 0.16 11.7 0.0 4.3 7.1 0.0 2.7 2 0 0 2 2 2 0 HeH/LEM domain PhetRS_B1 PF18262.1 OAP57980.1 - 0.18 12.0 0.0 2.1 8.6 0.0 2.6 2 1 0 2 2 2 0 Phe-tRNA synthetase beta subunit B1 domain Git3 PF11710.8 OAP57981.1 - 1.7e-08 34.5 9.8 1.7e-08 34.5 9.8 1.8 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 Dicty_CAR PF05462.11 OAP57981.1 - 8.2e-08 31.7 6.3 8.2e-08 31.7 6.3 2.0 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor DUF3357 PF11837.8 OAP57981.1 - 0.1 13.1 0.5 0.72 10.3 0.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) TRI12 PF06609.13 OAP57982.1 - 2.2e-34 118.9 11.4 2.6e-34 118.6 11.4 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAP57982.1 - 9.8e-19 67.5 53.3 1.1e-18 67.3 42.5 3.1 1 1 1 2 2 2 2 Major Facilitator Superfamily HHH_5 PF14520.6 OAP57982.1 - 0.022 15.4 0.3 0.045 14.3 0.3 1.4 1 0 0 1 1 1 0 Helix-hairpin-helix domain Lactonase PF10282.9 OAP57983.1 - 0.0013 18.1 0.0 0.04 13.2 0.0 2.8 2 2 1 3 3 3 1 Lactonase, 7-bladed beta-propeller DUF1815 PF08844.10 OAP57983.1 - 0.089 12.8 0.1 0.16 12.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1815) bZIP_1 PF00170.21 OAP57984.1 - 0.0012 18.8 8.3 0.0023 18.0 8.3 1.4 1 0 0 1 1 1 1 bZIP transcription factor G-gamma PF00631.22 OAP57984.1 - 0.021 14.8 0.1 0.021 14.8 0.1 1.8 2 0 0 2 2 2 0 GGL domain APG6_N PF17675.1 OAP57984.1 - 0.083 13.4 2.8 0.14 12.6 2.8 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region SlyX PF04102.12 OAP57984.1 - 0.64 10.7 3.6 0.56 10.9 1.3 2.0 1 1 1 2 2 2 0 SlyX ADIP PF11559.8 OAP57984.1 - 1.2 9.2 6.5 2.9 8.0 6.0 1.7 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding CENP-Q PF13094.6 OAP57984.1 - 2.3 8.4 6.4 3.3 7.9 0.3 2.3 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit BAG PF02179.16 OAP57986.1 - 1.8e-13 50.7 0.0 3.6e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 BAG domain ubiquitin PF00240.23 OAP57986.1 - 0.00084 19.0 0.0 0.0015 18.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family DUF5519 PF17648.1 OAP57987.1 - 0.00037 20.3 0.1 0.00069 19.5 0.1 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5519) LIAS_N PF16881.5 OAP57988.1 - 3.8e-26 91.6 0.0 6.8e-26 90.8 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 OAP57988.1 - 1.5e-13 51.5 0.0 2.3e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily DUF848 PF05852.11 OAP57988.1 - 0.15 12.2 0.0 8 6.6 0.0 2.2 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) SelK_SelG PF10961.8 OAP57989.1 - 1e-08 35.6 11.6 6.7e-06 26.6 11.6 2.3 1 1 0 1 1 1 1 Selenoprotein SelK_SelG Meth_synt_2 PF01717.18 OAP57990.1 - 0.00097 18.5 0.0 0.028 13.7 0.0 2.1 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain TPR_MLP1_2 PF07926.12 OAP57992.1 - 1.2e-33 116.0 31.4 1.2e-33 116.0 31.4 19.3 9 6 8 17 17 17 3 TPR/MLP1/MLP2-like protein PKcGMP_CC PF16808.5 OAP57992.1 - 0.005 16.7 1.6 0.005 16.7 1.6 11.1 12 0 0 12 12 12 2 Coiled-coil N-terminus of cGMP-dependent protein kinase HALZ PF02183.18 OAP57992.1 - 0.014 15.6 0.4 0.014 15.6 0.4 16.0 19 1 0 19 19 19 0 Homeobox associated leucine zipper Mto2_bdg PF12808.7 OAP57992.1 - 0.014 15.6 0.3 0.014 15.6 0.3 16.8 17 3 4 21 21 21 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Uteroglobin PF01099.17 OAP57992.1 - 0.024 14.9 0.1 0.024 14.9 0.1 5.5 6 1 1 7 7 7 0 Uteroglobin family DUF4279 PF14106.6 OAP57992.1 - 0.059 13.6 3.9 0.99 9.6 0.2 4.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4279) Guanylin PF02058.15 OAP57992.1 - 0.89 10.1 3.1 7.3 7.1 0.1 4.5 2 0 0 2 2 2 0 Guanylin precursor TFA2_Winged_2 PF18121.1 OAP57993.1 - 3.8e-21 74.5 0.6 2e-20 72.2 0.1 2.1 2 0 0 2 2 2 1 TFA2 Winged helix domain 2 TFIIE_beta PF02186.15 OAP57993.1 - 2.7e-06 27.6 0.1 1e-05 25.7 0.0 2.0 2 0 0 2 2 2 1 TFIIE beta subunit core domain DUF4834 PF16118.5 OAP57994.1 - 0.0074 17.2 0.0 0.016 16.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4834) DUF4381 PF14316.6 OAP57994.1 - 0.016 15.5 0.0 0.027 14.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) stn_TNFRSF12A PF12191.8 OAP57994.1 - 0.046 13.9 0.5 0.12 12.5 0.5 1.7 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain DUF2500 PF10694.9 OAP57994.1 - 0.072 13.6 0.0 0.13 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2500) PGF-CTERM PF18204.1 OAP57994.1 - 0.13 12.3 3.2 0.39 10.7 3.2 1.9 1 0 0 1 1 1 0 PGF-CTERM motif DUF2207 PF09972.9 OAP57994.1 - 0.2 10.4 0.0 0.24 10.1 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) RCR PF12273.8 OAP57994.1 - 1.1 9.9 9.6 5.3 7.7 9.7 2.1 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red Phage_holin_2_4 PF16082.5 OAP57994.1 - 7 6.5 7.5 0.13 12.0 0.6 1.7 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like DHBP_synthase PF00926.19 OAP57995.1 - 2.4e-85 284.9 0.1 2.8e-85 284.7 0.1 1.1 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase SIR2 PF02146.17 OAP57996.1 - 5.9e-31 107.8 0.0 9e-12 45.3 0.0 3.2 3 0 0 3 3 3 3 Sir2 family zf-trcl PF13451.6 OAP57996.1 - 0.24 11.3 1.5 0.52 10.2 1.5 1.5 1 0 0 1 1 1 0 Probable zinc-ribbon domain PIP49_C PF12260.8 OAP57997.1 - 0.022 14.4 0.0 0.035 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 Epimerase PF01370.21 OAP57999.1 - 7.4e-18 64.9 0.0 1.2e-17 64.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 OAP57999.1 - 2.3e-11 43.3 0.0 2.7e-11 43.1 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 OAP57999.1 - 6.4e-10 39.2 1.0 1.2e-09 38.3 1.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 OAP57999.1 - 5.4e-09 35.9 0.1 9.3e-07 28.6 0.1 2.5 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 OAP57999.1 - 1.5e-08 34.0 0.0 4.4e-07 29.2 0.0 2.1 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 OAP57999.1 - 6.3e-07 29.2 0.2 1.4e-06 28.0 0.2 1.5 2 0 0 2 2 2 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 OAP57999.1 - 4.1e-06 27.1 0.1 8.1e-06 26.1 0.1 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_4 PF07993.12 OAP57999.1 - 0.00011 21.5 0.1 0.00031 20.0 0.0 1.8 2 1 0 2 2 2 1 Male sterility protein TrkA_N PF02254.18 OAP57999.1 - 0.00062 20.0 0.1 0.0017 18.6 0.1 1.8 2 0 0 2 2 2 1 TrkA-N domain KR PF08659.10 OAP57999.1 - 0.0069 16.3 0.3 0.014 15.3 0.3 1.5 1 1 0 1 1 1 1 KR domain adh_short PF00106.25 OAP57999.1 - 0.011 15.2 0.1 0.017 14.6 0.1 1.4 1 0 0 1 1 1 0 short chain dehydrogenase ApbA PF02558.16 OAP57999.1 - 0.12 12.0 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA ResIII PF04851.15 OAP58000.1 - 4.7e-21 75.5 0.0 1.2e-20 74.2 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 OAP58000.1 - 6e-14 52.3 0.1 2.3e-12 47.2 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 OAP58000.1 - 6.3e-10 39.1 0.0 1.7e-09 37.7 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 OAP58000.1 - 0.0072 16.0 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 SWI2/SNF2 ATPase Iso_dh PF00180.20 OAP58001.1 - 5.8e-99 331.5 0.0 7.3e-99 331.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Sec5 PF15469.6 OAP58002.1 - 5e-36 124.3 0.0 3.1e-35 121.7 0.0 2.3 2 0 0 2 2 2 1 Exocyst complex component Sec5 Vps51 PF08700.11 OAP58002.1 - 8.8e-06 25.7 0.1 4.2e-05 23.5 0.1 2.3 2 0 0 2 2 2 1 Vps51/Vps67 Abi_C PF14355.6 OAP58002.1 - 0.029 14.5 0.0 0.15 12.2 0.0 2.3 1 0 0 1 1 1 0 Abortive infection C-terminus Eaf7 PF07904.13 OAP58003.1 - 3.7e-22 78.7 0.5 1.5e-21 76.8 0.0 2.2 2 0 0 2 2 2 1 Chromatin modification-related protein EAF7 NOA36 PF06524.12 OAP58003.1 - 2.6 7.3 7.5 3.3 7.0 7.5 1.1 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.12 OAP58003.1 - 3.1 5.9 9.3 3.7 5.6 9.3 1.2 1 0 0 1 1 1 0 Nop14-like family Clr5 PF14420.6 OAP58004.1 - 1.7e-05 24.9 0.0 4.2e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 Clr5 domain MFS_1 PF07690.16 OAP58005.1 - 3.9e-43 147.7 32.6 5.9e-43 147.1 32.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAP58005.1 - 1.1e-07 31.2 6.7 1.1e-07 31.2 6.7 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter VIT1 PF01988.19 OAP58005.1 - 0.0096 15.8 5.0 0.046 13.6 0.8 2.5 2 0 0 2 2 2 2 VIT family GCP_C_terminal PF04130.13 OAP58006.1 - 8.6e-67 225.8 6.0 8.6e-67 225.8 6.0 2.0 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 OAP58006.1 - 2.2e-05 24.3 7.1 0.00024 20.9 0.2 3.2 3 0 0 3 3 3 2 Gamma tubulin complex component N-terminal DUF3460 PF11943.8 OAP58006.1 - 0.013 15.8 0.2 0.029 14.6 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3460) DUF2236 PF09995.9 OAP58007.1 - 2.6e-33 116.2 0.2 5.8e-33 115.0 0.1 1.6 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2236) DUF2428 PF10350.9 OAP58007.1 - 0.26 10.5 0.5 4.9 6.3 0.0 2.4 3 0 0 3 3 3 0 Putative death-receptor fusion protein (DUF2428) Neugrin PF06413.11 OAP58008.1 - 2.3e-16 60.5 1.7 3.3e-16 60.0 1.7 1.4 1 0 0 1 1 1 1 Neugrin MRP-L20 PF12824.7 OAP58008.1 - 2e-10 41.0 2.9 3.6e-10 40.3 2.9 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Glyco_tranf_2_3 PF13641.6 OAP58009.1 - 1.2e-19 71.1 0.0 1.8e-19 70.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 OAP58009.1 - 3.8e-16 59.6 1.5 3.8e-16 59.6 1.5 1.9 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 OAP58009.1 - 8e-14 51.8 0.0 1.3e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Cellulose_synt PF03552.14 OAP58009.1 - 2.6e-10 39.5 3.3 1.4e-08 33.8 0.1 2.8 2 1 1 3 3 3 2 Cellulose synthase Glyco_transf_21 PF13506.6 OAP58009.1 - 3.3e-09 36.4 0.0 7.2e-09 35.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 21 DUF2275 PF10039.9 OAP58009.1 - 0.23 11.5 0.0 0.43 10.6 0.0 1.3 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2275) Acyl-CoA_ox_N PF14749.6 OAP58010.1 - 4.6e-21 75.7 0.1 1e-20 74.5 0.1 1.6 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal ACOX PF01756.19 OAP58010.1 - 2.4e-13 50.0 0.1 4.4e-13 49.2 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.19 OAP58010.1 - 3.7e-07 30.2 0.0 9e-07 29.0 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 OAP58010.1 - 4.2e-05 23.8 0.7 8.6e-05 22.8 0.7 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HET PF06985.11 OAP58011.1 - 1.1e-32 113.4 1.4 1.7e-32 112.8 1.4 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) FlgD_ig PF13860.6 OAP58012.1 - 0.038 13.9 0.0 0.085 12.7 0.0 1.6 1 0 0 1 1 1 0 FlgD Ig-like domain Adeno_E3_CR2 PF02439.15 OAP58013.1 - 0.087 12.6 0.5 0.21 11.4 0.5 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 SKG6 PF08693.10 OAP58013.1 - 1.6 8.2 6.2 1.4 8.4 3.4 2.3 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Abhydrolase_6 PF12697.7 OAP58014.1 - 2.7e-18 67.4 0.2 8.1e-18 65.8 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAP58014.1 - 7.2e-14 52.1 0.0 7.3e-11 42.2 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAP58014.1 - 3.4e-10 39.6 0.1 8.1e-09 35.1 0.1 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 OAP58014.1 - 0.00058 19.8 0.0 0.0012 18.8 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Mem_trans PF03547.18 OAP58015.1 - 5.3e-19 67.9 0.8 9.1e-10 37.5 0.0 2.1 2 0 0 2 2 2 2 Membrane transport protein Vac_ImportDeg PF09783.9 OAP58016.1 - 2e-25 89.5 0.0 6.9e-25 87.7 0.0 2.0 1 1 0 1 1 1 1 Vacuolar import and degradation protein Abhydrolase_1 PF00561.20 OAP58017.1 - 2.9e-22 79.5 0.0 3.9e-21 75.8 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAP58017.1 - 1.3e-10 42.3 0.2 1.7e-10 41.9 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAP58017.1 - 1.9e-09 37.1 0.0 1.1e-08 34.6 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 OAP58017.1 - 1.4e-06 28.3 0.0 3.3e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Esterase_phd PF10503.9 OAP58017.1 - 0.18 11.3 0.0 0.35 10.3 0.0 1.4 1 0 0 1 1 1 0 Esterase PHB depolymerase p450 PF00067.22 OAP58018.1 - 6.7e-59 199.8 0.0 1e-58 199.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 PHD PF00628.29 OAP58018.1 - 2.1e-10 40.3 7.2 2.1e-10 40.3 7.2 2.3 2 0 0 2 2 2 1 PHD-finger Tannase PF07519.11 OAP58019.1 - 1.7e-91 307.5 1.7 2.2e-91 307.1 1.7 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Sugar_tr PF00083.24 OAP58020.1 - 5.9e-92 308.9 14.5 7e-92 308.6 14.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP58020.1 - 9.1e-27 93.9 47.8 2.6e-23 82.5 25.9 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.18 OAP58021.1 - 2.8e-17 62.6 0.0 4.7e-17 61.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP58021.1 - 2e-09 37.4 12.8 3.6e-09 36.6 12.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PSI_integrin PF17205.3 OAP58021.1 - 0.0047 16.6 1.0 0.0047 16.6 1.0 2.6 3 0 0 3 3 3 1 Integrin plexin domain YscO PF07321.12 OAP58021.1 - 0.049 13.6 0.7 0.11 12.5 0.7 1.5 1 0 0 1 1 1 0 Type III secretion protein YscO Filo_glycop PF01611.16 OAP58021.1 - 0.052 12.5 0.0 0.098 11.6 0.0 1.4 1 0 0 1 1 1 0 Filovirus glycoprotein CENP-H PF05837.12 OAP58021.1 - 0.069 13.6 0.2 0.21 12.0 0.2 1.8 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DUF4551 PF15087.6 OAP58021.1 - 0.085 11.7 1.5 0.13 11.1 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Str_synth PF03088.16 OAP58021.1 - 0.11 12.7 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 Strictosidine synthase Opy2 PF09463.10 OAP58021.1 - 5.9 7.3 7.3 1.1 9.6 3.0 2.0 2 0 0 2 2 2 0 Opy2 protein AtuA PF07287.11 OAP58022.1 - 1.1e-125 419.0 0.1 1.4e-125 418.7 0.1 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA FAD_binding_3 PF01494.19 OAP58023.1 - 4.8e-88 295.7 0.0 9.5e-88 294.8 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 OAP58023.1 - 1.7e-55 187.6 0.0 3.2e-55 186.7 0.0 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox_2 PF07992.14 OAP58023.1 - 7.4e-05 22.1 0.4 0.00085 18.6 0.1 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAP58023.1 - 0.00049 18.9 0.1 0.00078 18.3 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 OAP58023.1 - 0.0011 18.3 0.0 0.035 13.3 0.0 2.2 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 OAP58023.1 - 0.0017 17.5 0.0 0.0029 16.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 OAP58023.1 - 0.0037 16.4 0.0 0.0083 15.2 0.0 1.6 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 OAP58023.1 - 0.0055 16.0 0.0 0.0087 15.3 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAP58023.1 - 0.035 14.3 0.0 0.21 11.8 0.0 2.3 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 OAP58023.1 - 0.093 13.3 0.0 0.27 11.8 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF3425 PF11905.8 OAP58024.1 - 1e-12 48.1 0.7 3.6e-12 46.3 0.0 2.2 3 0 0 3 3 3 1 Domain of unknown function (DUF3425) zf-C2H2 PF00096.26 OAP58025.1 - 2.3e-12 46.6 13.3 5.9e-06 26.4 4.3 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAP58025.1 - 2.8e-10 40.1 11.0 0.00011 22.7 0.8 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 OAP58025.1 - 7.2e-08 32.6 3.1 0.001 19.4 0.1 2.6 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 OAP58025.1 - 1.1e-07 31.9 0.7 0.011 15.9 0.7 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 OAP58025.1 - 1.3e-07 31.5 6.4 0.0022 17.9 0.1 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OAP58025.1 - 3.3e-06 27.3 15.1 3.5e-06 27.2 3.4 3.2 3 0 0 3 3 3 1 Zinc-finger double domain Zn-C2H2_12 PF18112.1 OAP58025.1 - 2.5e-05 24.6 0.5 0.18 12.3 0.0 3.0 2 0 0 2 2 2 2 Autophagy receptor zinc finger-C2H2 domain zf-Di19 PF05605.12 OAP58025.1 - 0.00047 20.4 3.5 0.0011 19.3 3.5 1.6 1 1 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding Rad50_zn_hook PF04423.14 OAP58025.1 - 0.0016 18.3 4.3 0.57 10.1 0.4 2.3 2 0 0 2 2 2 2 Rad50 zinc hook motif zf-C2HC_2 PF13913.6 OAP58025.1 - 0.007 16.2 1.8 0.024 14.5 0.0 2.3 2 0 0 2 2 2 1 zinc-finger of a C2HC-type zf-C2H2_9 PF16293.5 OAP58025.1 - 0.01 15.6 0.8 3.2 7.7 0.1 2.4 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) zf-MYST PF17772.1 OAP58025.1 - 0.018 14.6 0.6 2.5 7.8 0.1 2.4 2 0 0 2 2 2 0 MYST family zinc finger domain DUF2225 PF09986.9 OAP58025.1 - 0.086 12.5 2.4 1 9.0 0.5 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-RING_2 PF13639.6 OAP58025.1 - 0.092 13.1 0.2 17 5.8 0.0 2.3 2 0 0 2 2 2 0 Ring finger domain zf-C2H2_2 PF12756.7 OAP58025.1 - 0.14 12.5 1.9 9.1 6.7 0.1 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Prok-RING_4 PF14447.6 OAP58025.1 - 0.16 11.8 1.7 4 7.4 0.1 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 LIM PF00412.22 OAP58025.1 - 0.26 11.6 1.0 0.44 10.8 1.0 1.3 1 0 0 1 1 1 0 LIM domain Ldh_1_N PF00056.23 OAP58026.1 - 9.2e-28 97.1 0.1 2.8e-27 95.5 0.1 1.8 1 1 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 OAP58026.1 - 1.7e-18 67.1 0.0 2.5e-18 66.6 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain F420_oxidored PF03807.17 OAP58026.1 - 0.043 14.4 0.1 0.19 12.3 0.1 2.1 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent XPC-binding PF09280.11 OAP58026.1 - 0.054 13.2 1.1 0.088 12.6 1.1 1.3 1 0 0 1 1 1 0 XPC-binding domain Sacchrp_dh_NADP PF03435.18 OAP58026.1 - 0.061 13.6 0.7 0.69 10.2 0.1 2.5 3 0 0 3 3 3 0 Saccharopine dehydrogenase NADP binding domain DAO PF01266.24 OAP58026.1 - 0.061 12.9 2.4 0.11 12.1 0.6 2.0 1 1 1 2 2 2 0 FAD dependent oxidoreductase CtsR PF05848.11 OAP58026.1 - 0.1 12.5 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 CtsR N-terminal HTH domain PPDK_N PF01326.19 OAP58027.1 - 5.3e-111 371.0 0.0 7.5e-111 370.5 0.0 1.2 1 0 0 1 1 1 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain PEP-utilizers_C PF02896.18 OAP58027.1 - 1.4e-60 204.9 0.0 2.3e-60 204.2 0.0 1.3 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PEP-utilizers PF00391.23 OAP58027.1 - 1.1e-25 89.1 1.0 2.9e-25 87.8 1.0 1.8 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain zf-C2H2 PF00096.26 OAP58028.1 - 9e-07 29.0 18.0 3e-05 24.2 2.7 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OAP58028.1 - 4.2e-05 23.8 3.8 4.2e-05 23.8 3.8 2.4 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 OAP58028.1 - 0.00011 22.8 1.8 0.00011 22.8 1.8 3.3 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OAP58028.1 - 0.0015 18.7 0.7 0.0015 18.7 0.7 1.8 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 OAP58028.1 - 0.036 14.7 1.7 0.036 14.7 1.7 3.4 2 1 2 4 4 4 0 FOXP coiled-coil domain zf-C2H2_6 PF13912.6 OAP58028.1 - 0.056 13.5 1.7 0.12 12.4 1.7 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_8 PF15909.5 OAP58028.1 - 0.087 13.1 4.2 0.27 11.5 4.3 1.8 1 1 0 1 1 1 0 C2H2-type zinc ribbon zf-TRAF PF02176.18 OAP58028.1 - 0.58 10.9 8.2 0.26 12.0 2.6 2.3 2 0 0 2 2 2 0 TRAF-type zinc finger zf-C2H2_2 PF12756.7 OAP58028.1 - 7.2 7.0 7.2 27 5.2 5.5 2.5 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Fungal_trans PF04082.18 OAP58029.1 - 1e-25 90.3 0.0 1.8e-25 89.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP58029.1 - 2.5e-11 43.5 12.6 4.7e-11 42.6 12.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.13 OAP58029.1 - 0.29 11.3 2.7 0.47 10.7 0.1 2.6 3 0 0 3 3 3 0 Gal4-like dimerisation domain Sugar_tr PF00083.24 OAP58030.1 - 3e-99 332.9 12.4 3.7e-99 332.6 12.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP58030.1 - 1.6e-27 96.4 16.8 1.6e-27 96.4 16.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 OAP58030.1 - 9.7e-05 21.0 1.0 0.0002 19.9 1.0 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) SPC25 PF06703.11 OAP58030.1 - 0.72 9.6 4.5 0.16 11.8 0.2 2.1 3 0 0 3 3 3 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Ras PF00071.22 OAP58032.1 - 6.6e-56 188.4 0.0 7.5e-56 188.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAP58032.1 - 1.5e-21 76.8 0.0 2.3e-21 76.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAP58032.1 - 2.2e-08 33.8 0.0 2.6e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OAP58032.1 - 0.0025 17.4 0.0 0.0063 16.1 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain RRM_1 PF00076.22 OAP58033.1 - 4.9e-18 64.7 0.0 8.7e-18 63.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OAP58033.1 - 0.013 15.6 0.0 0.031 14.4 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif PHM7_cyt PF14703.6 OAP58033.1 - 2.9 8.1 14.2 2.2 8.5 0.1 3.5 3 1 1 4 4 4 0 Cytosolic domain of 10TM putative phosphate transporter Pkinase PF00069.25 OAP58034.1 - 3.1e-40 138.2 0.0 4.8e-40 137.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP58034.1 - 2e-27 96.1 0.0 2.9e-27 95.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OAP58034.1 - 0.0017 17.8 0.0 0.0031 16.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OAP58034.1 - 0.011 15.1 0.0 0.018 14.3 0.0 1.3 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 OAP58034.1 - 0.049 13.5 1.5 12 5.7 0.0 3.4 2 2 1 3 3 3 0 Phosphotransferase enzyme family Med10 PF09748.9 OAP58035.1 - 9.5e-34 116.0 0.1 1.4e-33 115.4 0.1 1.3 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex Chalcone_2 PF16035.5 OAP58036.1 - 1.9e-76 256.4 0.0 2.6e-76 256.0 0.0 1.2 1 0 0 1 1 1 1 Chalcone isomerase like Auts2 PF15336.6 OAP58036.1 - 0.0012 19.0 2.6 0.0069 16.5 0.7 2.3 2 0 0 2 2 2 1 Autism susceptibility gene 2 protein Chalcone_3 PF16036.5 OAP58036.1 - 0.012 15.7 0.0 0.49 10.5 0.0 2.4 2 0 0 2 2 2 0 Chalcone isomerase-like Glutaredoxin PF00462.24 OAP58037.1 - 3.2e-18 65.7 0.0 4.6e-18 65.2 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin DUF836 PF05768.14 OAP58037.1 - 0.0054 17.1 0.1 0.0073 16.7 0.1 1.4 1 1 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_4 PF13462.6 OAP58037.1 - 0.011 15.8 0.2 1.4 9.0 0.1 2.1 2 0 0 2 2 2 0 Thioredoxin Thioredoxin_2 PF13098.6 OAP58037.1 - 0.013 15.9 0.1 0.031 14.7 0.1 1.7 1 1 0 1 1 1 0 Thioredoxin-like domain DSBA PF01323.20 OAP58037.1 - 0.056 13.2 0.2 0.55 10.0 0.2 2.0 1 1 1 2 2 2 0 DSBA-like thioredoxin domain Thioredoxin_3 PF13192.6 OAP58037.1 - 0.059 13.4 0.0 0.094 12.8 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin domain Thioredoxin PF00085.20 OAP58037.1 - 0.079 13.0 0.0 0.083 12.9 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin TraF PF13728.6 OAP58037.1 - 0.11 12.3 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein Thioredoxin_9 PF14595.6 OAP58037.1 - 0.14 11.9 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin DnaJ PF00226.31 OAP58039.1 - 3e-20 72.1 1.2 6.6e-20 71.0 1.2 1.6 1 0 0 1 1 1 1 DnaJ domain zf-UBR PF02207.20 OAP58040.1 - 0.78 10.0 8.6 0.055 13.6 3.0 2.0 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) Lipase_3 PF01764.25 OAP58041.1 - 8e-17 61.4 0.0 1.3e-16 60.8 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 OAP58041.1 - 0.0011 19.7 0.2 0.0016 19.1 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 OAP58041.1 - 0.14 11.8 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein OrfB_Zn_ribbon PF07282.11 OAP58042.1 - 0.042 13.8 0.6 0.042 13.8 0.6 3.2 2 2 1 3 3 3 0 Putative transposase DNA-binding domain DUF2207 PF09972.9 OAP58042.1 - 6.8 5.3 4.8 9.6 4.8 4.8 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Methyltransf_23 PF13489.6 OAP58043.1 - 4.3e-21 75.5 0.0 5.8e-21 75.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAP58043.1 - 1.3e-12 48.2 0.0 3.7e-12 46.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAP58043.1 - 4.7e-09 36.9 0.0 1.3e-07 32.3 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAP58043.1 - 1.3e-08 35.4 0.0 2.8e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAP58043.1 - 1.8e-06 27.8 0.0 0.031 14.1 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_16 PF10294.9 OAP58043.1 - 0.028 14.2 0.0 0.043 13.5 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase PrmA PF06325.13 OAP58043.1 - 0.03 13.7 0.0 0.052 12.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 OAP58043.1 - 0.03 13.9 0.0 0.051 13.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Ubie_methyltran PF01209.18 OAP58043.1 - 0.032 13.6 0.0 0.49 9.7 0.0 2.1 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family p450 PF00067.22 OAP58044.1 - 4e-63 213.8 0.0 5e-63 213.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HET PF06985.11 OAP58045.1 - 1.5e-06 28.6 0.1 0.018 15.4 0.0 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) HET PF06985.11 OAP58046.1 - 2.4e-24 86.3 0.0 8.8e-24 84.5 0.0 2.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) TPR_12 PF13424.6 OAP58046.1 - 1.3e-13 51.0 2.9 0.00055 20.2 0.1 4.8 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_10 PF13374.6 OAP58046.1 - 0.00016 21.4 8.7 1.8 8.6 0.0 6.3 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.6 OAP58046.1 - 0.0025 18.5 0.3 89 4.3 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 OAP58046.1 - 0.0056 17.2 2.7 1 9.9 0.0 3.9 5 0 0 5 5 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 OAP58046.1 - 0.026 14.8 5.2 2.4 8.5 1.0 3.3 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 OAP58046.1 - 0.61 10.3 4.0 4.3 7.7 0.1 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 OAP58046.1 - 0.92 10.3 4.9 6 7.7 0.1 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Sigma70_r3 PF04539.16 OAP58046.1 - 7.7 6.7 8.4 7.9 6.7 0.4 2.7 2 0 0 2 2 2 0 Sigma-70 region 3 DUF3883 PF13020.6 OAP58047.1 - 0.0034 17.4 0.0 0.012 15.6 0.0 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF3883) HET PF06985.11 OAP58048.1 - 3.7e-21 76.0 0.0 6.8e-21 75.1 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.7 OAP58048.1 - 8.6e-08 32.7 0.0 0.0031 18.1 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 OAP58048.1 - 2.1e-06 27.9 0.1 0.36 11.4 0.0 4.6 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 OAP58048.1 - 3.6e-06 27.4 0.3 0.0032 18.0 0.1 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OAP58048.1 - 3.5e-05 24.0 0.0 0.00047 20.4 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAP58048.1 - 6.3e-05 23.1 1.1 0.61 10.8 0.0 4.2 5 0 0 5 5 5 2 Ankyrin repeat ADH_N PF08240.12 OAP58049.1 - 9.5e-26 89.8 1.4 2.2e-25 88.7 1.4 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAP58049.1 - 1e-20 74.0 0.2 2.1e-20 73.0 0.2 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAP58049.1 - 6.6e-07 30.5 0.0 1.1e-06 29.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 OAP58049.1 - 0.015 14.6 0.7 0.024 13.9 0.7 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Cript PF10235.9 OAP58049.1 - 0.21 12.1 1.1 0.36 11.4 1.1 1.3 1 0 0 1 1 1 0 Microtubule-associated protein CRIPT DUF3425 PF11905.8 OAP58050.1 - 1.8e-23 82.8 0.6 3.7e-23 81.8 0.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 OAP58050.1 - 0.0043 17.1 9.6 0.013 15.5 9.3 1.9 1 1 1 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 OAP58050.1 - 0.091 12.9 7.6 1.1 9.4 4.9 2.3 2 0 0 2 2 2 0 Basic region leucine zipper DUF2514 PF10721.9 OAP58050.1 - 0.12 12.4 4.6 0.28 11.2 4.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) Fmp27_WPPW PF10359.9 OAP58050.1 - 0.18 10.6 1.9 0.28 10.0 1.9 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF1690 PF07956.11 OAP58050.1 - 4.4 7.7 7.0 8.1 6.9 7.0 1.3 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) Sugar_tr PF00083.24 OAP58051.1 - 2.8e-76 257.2 20.3 3.5e-76 256.9 20.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP58051.1 - 1.3e-18 67.1 39.6 5.6e-14 51.8 6.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Cellulase PF00150.18 OAP58052.1 - 2e-08 34.0 0.0 3.8e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) JSRP PF15312.6 OAP58052.1 - 0.039 13.9 0.0 0.2 11.6 0.0 2.2 2 0 0 2 2 2 0 Junctional sarcoplasmic reticulum protein Myotub-related PF06602.14 OAP58053.1 - 3.4e-149 496.6 0.0 4.2e-149 496.3 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain GRAM PF02893.20 OAP58053.1 - 0.075 12.9 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 GRAM domain DSPc PF00782.20 OAP58054.1 - 1.1e-21 77.1 0.0 2.4e-20 72.7 0.0 2.3 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Peptidase_M15 PF01427.17 OAP58055.1 - 0.12 12.1 0.0 0.14 11.9 0.0 1.1 1 0 0 1 1 1 0 D-ala-D-ala dipeptidase Metallophos PF00149.28 OAP58057.1 - 1.3e-10 42.2 0.6 2.4e-10 41.3 0.6 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OAP58057.1 - 2.6e-06 27.7 0.1 6.8e-05 23.1 0.1 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain CDO_I PF05995.12 OAP58059.1 - 1.9e-42 144.4 0.0 2.6e-42 144.0 0.0 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I PCO_ADO PF07847.12 OAP58059.1 - 8.3e-05 22.1 0.1 0.00012 21.6 0.1 1.2 1 0 0 1 1 1 1 PCO_ADO MMR_HSR1_Xtn PF16897.5 OAP58060.1 - 5.9e-40 135.6 1.9 2.5e-39 133.6 0.7 2.2 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 OAP58060.1 - 3.7e-23 81.4 0.1 7.1e-23 80.4 0.1 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 OAP58060.1 - 7.8e-21 74.3 0.1 2.8e-20 72.5 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OAP58060.1 - 4.2e-09 36.1 0.1 2.6e-08 33.6 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 OAP58060.1 - 0.00046 19.8 0.1 4.4 6.8 0.0 3.7 2 2 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 OAP58060.1 - 0.0015 18.6 0.1 0.35 10.9 0.0 2.5 1 1 1 2 2 2 2 Dynamin family MeaB PF03308.16 OAP58060.1 - 0.005 15.9 0.7 0.017 14.1 0.1 2.0 2 1 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_GTPase PF03193.16 OAP58060.1 - 0.11 12.4 0.8 3.3 7.6 0.1 2.8 2 1 1 3 3 3 0 RsgA GTPase DUF211 PF02680.14 OAP58060.1 - 0.14 12.3 2.0 0.27 11.4 0.6 2.3 2 1 1 3 3 3 0 Uncharacterized ArCR, COG1888 HTH_Tnp_Tc5 PF03221.16 OAP58061.1 - 3.3e-10 39.8 0.2 6.3e-10 38.9 0.2 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 OAP58061.1 - 0.00046 19.7 1.4 0.00046 19.7 1.4 1.9 3 0 0 3 3 3 1 CENP-B N-terminal DNA-binding domain MarR PF01047.22 OAP58061.1 - 0.00092 19.1 0.0 0.0021 18.0 0.0 1.5 1 0 0 1 1 1 1 MarR family HTH_38 PF13936.6 OAP58061.1 - 0.0071 16.1 0.5 0.014 15.1 0.5 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 OAP58061.1 - 0.012 15.4 0.3 0.043 13.6 0.0 2.0 2 0 0 2 2 2 0 Homeodomain-like domain Sigma70_r4 PF04545.16 OAP58061.1 - 0.028 13.9 0.2 0.053 13.0 0.2 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_Tnp_4 PF13613.6 OAP58061.1 - 0.1 12.3 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease PXA PF02194.15 OAP58062.1 - 8.4e-47 159.5 1.7 9.4e-47 159.3 0.9 1.5 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.12 OAP58062.1 - 0.094 13.3 0.0 0.31 11.6 0.0 2.0 2 0 0 2 2 2 0 Sorting nexin C terminal Tom5 PF10642.9 OAP58062.1 - 0.56 10.3 1.9 2.8 8.1 0.1 2.8 3 0 0 3 3 3 0 Mitochondrial import receptor subunit or translocase IU_nuc_hydro PF01156.19 OAP58063.1 - 2.4e-79 267.1 0.0 2.8e-79 266.8 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase A_deamin PF02137.18 OAP58064.1 - 5.9e-05 22.7 0.3 0.0002 20.9 0.3 1.7 1 1 0 1 1 1 1 Adenosine-deaminase (editase) domain Fungal_trans PF04082.18 OAP58065.1 - 4.9e-26 91.4 0.0 9.4e-26 90.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP58065.1 - 3.2e-09 36.7 10.6 5.2e-09 36.1 10.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Man-6-P_recep PF02157.15 OAP58066.1 - 6.8e-13 48.3 0.0 8.8e-13 47.9 0.0 1.3 1 1 0 1 1 1 1 Mannose-6-phosphate receptor ATG27 PF09451.10 OAP58066.1 - 2e-12 47.6 0.0 3.5e-12 46.7 0.0 1.5 1 1 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.18 OAP58066.1 - 0.00033 20.7 0.0 0.0067 16.5 0.0 2.2 2 1 0 2 2 2 1 Cation-independent mannose-6-phosphate receptor repeat ERG4_ERG24 PF01222.17 OAP58067.1 - 3.1e-158 527.1 0.8 3.6e-158 526.8 0.8 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 OAP58067.1 - 0.0013 18.3 0.8 0.0055 16.3 0.4 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) MFS_1 PF07690.16 OAP58068.1 - 2.7e-25 89.1 20.5 2.7e-25 89.1 20.5 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 OAP58068.1 - 6.1e-06 24.9 2.2 6.1e-06 24.9 2.2 2.2 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF5631 PF18645.1 OAP58068.1 - 0.045 14.1 0.1 21 5.6 0.0 3.4 3 0 0 3 3 3 0 Family of unknown function (DUF5631) adh_short PF00106.25 OAP58069.1 - 3.8e-49 166.8 0.0 4.6e-49 166.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP58069.1 - 7.5e-31 107.5 0.0 1e-30 107.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP58069.1 - 4.6e-09 36.4 0.0 6.7e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAP58069.1 - 0.00096 18.7 0.0 0.0014 18.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family AMP-binding PF00501.28 OAP58070.1 - 1.8e-74 250.9 0.0 2.2e-74 250.6 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAP58070.1 - 3.1e-12 47.3 0.1 3.5e-11 43.9 0.0 2.7 2 1 1 3 3 3 1 AMP-binding enzyme C-terminal domain Methyltransf_22 PF13383.6 OAP58070.1 - 0.12 11.9 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain CoA_transf_3 PF02515.17 OAP58071.1 - 4.8e-66 223.4 0.1 1.5e-65 221.7 0.1 1.6 1 1 0 1 1 1 1 CoA-transferase family III DUF4834 PF16118.5 OAP58071.1 - 0.3 12.1 4.3 0.82 10.7 4.3 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF2207 PF09972.9 OAP58071.1 - 0.33 9.6 0.9 0.34 9.6 0.9 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) p450 PF00067.22 OAP58072.1 - 5.8e-70 236.3 0.0 7.2e-70 236.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 OAP58073.1 - 1.2e-72 245.2 0.0 1.6e-72 244.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SabA_adhesion PF18304.1 OAP58074.1 - 0.043 13.1 0.0 0.043 13.1 0.0 1.0 1 0 0 1 1 1 0 SabA N-terminal extracellular adhesion domain SUR7 PF06687.12 OAP58075.1 - 7.5e-36 123.8 3.8 9.2e-36 123.5 3.8 1.1 1 0 0 1 1 1 1 SUR7/PalI family Clc-like PF07062.12 OAP58075.1 - 0.0047 16.4 1.1 0.0072 15.8 1.1 1.3 1 0 0 1 1 1 1 Clc-like Amastin PF07344.11 OAP58075.1 - 0.21 11.4 9.2 0.42 10.4 9.2 1.5 1 0 0 1 1 1 0 Amastin surface glycoprotein Fig1 PF12351.8 OAP58075.1 - 2.3 8.1 7.5 0.041 13.8 0.6 1.6 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 Phage_holin_3_6 PF07332.11 OAP58075.1 - 2.7 8.1 14.7 1.3 9.1 4.5 2.7 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III Anoctamin PF04547.12 OAP58075.1 - 7.9 5.2 7.4 10 4.9 7.4 1.2 1 0 0 1 1 1 0 Calcium-activated chloride channel Rogdi_lz PF10259.9 OAP58076.1 - 6.2e-84 281.6 0.1 7.1e-84 281.4 0.1 1.0 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein AMP-binding PF00501.28 OAP58078.1 - 4.3e-57 193.6 0.0 6.1e-57 193.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAP58078.1 - 0.0017 19.3 0.1 0.0041 18.1 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Thiolase_N PF00108.23 OAP58079.1 - 4.1e-62 209.9 0.1 6.9e-62 209.2 0.1 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 OAP58079.1 - 3.8e-47 159.0 0.1 8.8e-47 157.8 0.1 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III_C PF08541.10 OAP58079.1 - 0.0018 18.4 0.0 0.0053 16.9 0.0 1.8 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Cupin_2 PF07883.11 OAP58080.1 - 2e-10 40.3 0.0 3.3e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 OAP58080.1 - 1.6e-05 24.8 0.0 2.2e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_3 PF05899.12 OAP58080.1 - 0.036 13.7 0.0 0.064 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF861) CENP-C_C PF11699.8 OAP58080.1 - 0.11 12.7 0.0 0.25 11.6 0.0 1.6 1 0 0 1 1 1 0 Mif2/CENP-C like EutQ PF06249.12 OAP58080.1 - 0.13 12.0 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutQ Glyco_hydro_1 PF00232.18 OAP58081.1 - 7.5e-157 522.4 0.0 9.9e-157 522.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 MFS_2 PF13347.6 OAP58082.1 - 2e-11 43.1 4.7 2e-11 43.1 4.7 2.5 3 0 0 3 3 3 1 MFS/sugar transport protein MFS_1 PF07690.16 OAP58082.1 - 1.9e-08 33.7 14.4 1.9e-08 33.7 14.4 2.9 2 1 0 3 3 3 1 Major Facilitator Superfamily BT1 PF03092.16 OAP58082.1 - 0.0016 16.8 3.2 0.18 10.0 0.1 2.8 3 0 0 3 3 3 2 BT1 family PUCC PF03209.15 OAP58082.1 - 0.002 17.2 1.4 0.002 17.2 1.4 1.9 2 0 0 2 2 2 1 PUCC protein DUF1146 PF06612.11 OAP58082.1 - 0.12 12.4 0.2 0.12 12.4 0.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1146) DUF2518 PF10726.9 OAP58082.1 - 0.64 9.7 2.7 0.55 9.9 0.3 2.1 2 0 0 2 2 2 0 Protein of function (DUF2518) Yip1 PF04893.17 OAP58083.1 - 0.0074 16.0 2.5 0.0084 15.8 2.5 1.1 1 0 0 1 1 1 1 Yip1 domain MIG-14_Wnt-bd PF06664.12 OAP58083.1 - 0.0081 15.4 0.1 0.0086 15.3 0.1 1.0 1 0 0 1 1 1 1 Wnt-binding factor required for Wnt secretion DUF3149 PF11346.8 OAP58083.1 - 0.1 12.3 2.3 0.18 11.4 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3149) CoA_binding PF02629.19 OAP58084.1 - 8.3e-27 93.7 3.9 8.7e-27 93.7 0.6 2.2 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 OAP58084.1 - 7.9e-23 81.0 0.4 1.2e-22 80.4 0.4 1.3 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 OAP58084.1 - 1.2e-07 31.6 0.1 2.2e-07 30.7 0.1 1.4 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 OAP58084.1 - 0.0015 19.0 0.0 0.0038 17.7 0.0 1.7 1 0 0 1 1 1 1 CoA binding domain Sugar_tr PF00083.24 OAP58085.1 - 1.2e-104 350.7 32.1 1.4e-104 350.5 32.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP58085.1 - 2.7e-33 115.4 25.4 2.7e-33 115.4 25.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily V-SNARE PF05008.15 OAP58085.1 - 0.02 15.3 0.5 0.035 14.5 0.5 1.4 1 0 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus Fungal_trans_2 PF11951.8 OAP58086.1 - 2.1e-07 30.1 0.0 4.4e-07 29.0 0.0 1.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain Holin_2-3 PF13272.6 OAP58086.1 - 0.22 11.8 0.8 2.6 8.4 0.1 2.4 2 0 0 2 2 2 0 Putative 2/3 transmembrane domain holin p450 PF00067.22 OAP58087.1 - 1.3e-57 195.7 0.0 1.7e-57 195.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 APG17 PF04108.12 OAP58087.1 - 0.16 11.0 0.0 0.24 10.4 0.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg17 Radical_SAM_C PF16199.5 OAP58088.1 - 1.5e-32 111.4 0.0 3.9e-32 110.1 0.0 1.7 2 0 0 2 2 2 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 OAP58088.1 - 7.5e-20 72.0 0.0 2e-19 70.6 0.0 1.6 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 OAP58088.1 - 2.9e-11 43.6 0.0 6.7e-11 42.5 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OAP58088.1 - 2.3e-08 34.1 0.5 2.6e-06 27.4 0.1 3.3 3 1 0 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OAP58088.1 - 0.01 16.3 0.0 0.023 15.1 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain TP_methylase PF00590.20 OAP58089.1 - 1.5e-48 165.5 0.5 3.1e-48 164.5 0.5 1.5 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.6 OAP58089.1 - 2e-13 50.7 0.0 3.8e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_M PF14824.6 OAP58089.1 - 1.4e-10 40.4 0.1 4.4e-10 38.8 0.1 1.9 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Sirohm_synth_C PF14823.6 OAP58089.1 - 9.8e-10 37.9 0.0 5.6e-07 29.1 0.0 2.8 2 0 0 2 2 2 2 Sirohaem biosynthesis protein C-terminal adh_short PF00106.25 OAP58090.1 - 4.6e-31 107.8 0.0 1.4e-30 106.2 0.0 1.8 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP58090.1 - 1.3e-22 80.5 0.0 1e-21 77.6 0.0 2.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP58090.1 - 1.6e-06 28.2 0.1 0.026 14.4 0.0 2.5 3 0 0 3 3 3 2 KR domain Sod_Cu PF00080.20 OAP58090.1 - 0.042 14.0 0.0 0.12 12.5 0.0 1.7 2 0 0 2 2 2 0 Copper/zinc superoxide dismutase (SODC) Glyco_transf_90 PF05686.12 OAP58091.1 - 4.9e-21 75.1 2.5 2.1e-17 63.1 0.6 3.1 2 1 0 2 2 2 2 Glycosyl transferase family 90 MHC2-interact PF09307.10 OAP58091.1 - 0.044 13.8 0.2 0.077 13.0 0.2 1.3 1 0 0 1 1 1 0 CLIP, MHC2 interacting His_Phos_1 PF00300.22 OAP58092.1 - 8.9e-22 77.7 0.1 1.1e-21 77.4 0.1 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) HEAT PF02985.22 OAP58093.1 - 1.5e-35 118.2 15.3 0.014 15.6 0.1 12.3 13 0 0 13 13 13 10 HEAT repeat HEAT_2 PF13646.6 OAP58093.1 - 6e-34 116.3 6.2 1.7e-10 41.1 0.0 7.3 3 2 5 8 8 8 8 HEAT repeats Vac14_Fab1_bd PF12755.7 OAP58093.1 - 6.6e-12 45.9 3.3 0.00024 21.7 0.1 6.5 5 2 3 8 8 8 3 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 OAP58093.1 - 1.4e-10 41.5 10.2 0.022 15.2 0.0 7.7 6 3 3 9 9 8 2 HEAT-like repeat Cnd1 PF12717.7 OAP58093.1 - 2.7e-09 37.3 9.7 0.015 15.3 0.1 5.3 4 1 2 6 6 6 3 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 OAP58093.1 - 1.1e-07 31.7 1.0 0.086 12.4 0.1 4.1 3 1 1 4 4 4 2 CLASP N terminal RTP1_C1 PF10363.9 OAP58093.1 - 5.6e-06 26.5 5.5 0.94 9.7 0.2 4.6 4 1 1 5 5 5 3 Required for nuclear transport of RNA pol II C-terminus 1 Adaptin_N PF01602.20 OAP58093.1 - 6e-06 25.1 8.7 0.078 11.5 0.2 4.5 2 1 1 3 3 3 2 Adaptin N terminal region TetR_C_16 PF17920.1 OAP58093.1 - 0.011 15.9 0.1 10 6.4 0.0 3.2 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain MadL PF03817.13 OAP58093.1 - 0.082 12.9 0.1 0.22 11.5 0.1 1.7 2 0 0 2 2 2 0 Malonate transporter MadL subunit Proteasom_PSMB PF10508.9 OAP58093.1 - 0.12 10.8 3.0 0.53 8.7 0.0 2.5 2 1 0 2 2 2 0 Proteasome non-ATPase 26S subunit M11L PF11099.8 OAP58093.1 - 0.13 12.6 0.4 17 5.7 0.0 3.4 2 2 1 4 4 4 0 Apoptosis regulator M11L like Arm PF00514.23 OAP58093.1 - 1.7 8.8 5.9 5 7.3 0.0 3.9 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat tRNA_synthFbeta PF17759.1 OAP58094.1 - 3.5e-48 163.9 0.0 5.2e-48 163.3 0.0 1.3 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 OAP58094.1 - 7.4e-32 109.4 0.2 6.3e-30 103.2 0.1 2.6 2 0 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 OAP58094.1 - 9.8e-27 93.7 0.0 1.7e-26 93.0 0.0 1.4 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 OAP58094.1 - 2e-18 66.4 0.0 4.8e-16 58.8 0.0 2.6 2 0 0 2 2 2 2 tRNA synthetase B5 domain Ribosomal_S3_C PF00189.20 OAP58095.1 - 9.9e-25 86.9 0.1 4.9e-24 84.7 0.1 2.0 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 OAP58095.1 - 6.8e-12 45.0 0.1 1.2e-11 44.3 0.1 1.4 1 0 0 1 1 1 1 KH domain CoA_binding_2 PF13380.6 OAP58095.1 - 0.073 13.6 0.2 0.46 11.0 0.1 2.2 3 0 0 3 3 3 0 CoA binding domain UN_NPL4 PF11543.8 OAP58095.1 - 0.1 13.1 0.0 0.2 12.2 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Coilin_N PF15862.5 OAP58095.1 - 0.15 11.8 0.0 0.33 10.7 0.0 1.5 1 0 0 1 1 1 0 Coilin N-terminus DEAD PF00270.29 OAP58096.1 - 5.6e-42 143.5 0.0 3.7e-41 140.8 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAP58096.1 - 3.4e-25 88.6 0.0 1e-24 87.0 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AA_permease_2 PF13520.6 OAP58097.1 - 4.7e-55 187.1 54.4 5.8e-55 186.8 54.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAP58097.1 - 3.7e-17 62.1 45.6 4.9e-17 61.7 45.6 1.1 1 0 0 1 1 1 1 Amino acid permease IF2_assoc PF08364.11 OAP58097.1 - 0.098 12.9 0.2 0.17 12.2 0.2 1.3 1 0 0 1 1 1 0 Bacterial translation initiation factor IF-2 associated region Glyoxal_oxid_N PF07250.11 OAP58100.1 - 2.7e-18 66.0 0.0 6.3e-18 64.8 0.0 1.6 2 0 0 2 2 2 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 OAP58100.1 - 2.8e-16 59.6 0.0 4.4e-16 58.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Glyoxal_oxid_N PF07250.11 OAP58101.1 - 5.3e-19 68.4 0.0 1.3e-18 67.1 0.0 1.7 1 1 0 1 1 1 1 Glyoxal oxidase N-terminus Kelch_6 PF13964.6 OAP58101.1 - 0.071 13.4 0.6 22 5.5 0.0 3.0 2 1 1 3 3 3 0 Kelch motif HEAT PF02985.22 OAP58103.1 - 0.018 15.2 1.4 18 5.9 0.0 4.0 3 0 0 3 3 3 0 HEAT repeat SnoaL_2 PF12680.7 OAP58105.1 - 2.1e-06 28.3 0.8 3.1e-06 27.8 0.8 1.3 1 0 0 1 1 1 1 SnoaL-like domain Pyr_redox_2 PF07992.14 OAP58106.1 - 2.6e-33 115.5 0.0 5.1e-31 108.0 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAP58106.1 - 2.6e-12 47.1 0.0 1.2e-08 35.3 0.0 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAP58106.1 - 0.00016 21.8 0.0 0.25 11.6 0.0 2.9 3 0 0 3 3 3 2 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 OAP58106.1 - 0.0014 17.9 0.0 0.22 10.7 0.0 2.5 2 0 0 2 2 2 2 FAD binding domain FAD_binding_2 PF00890.24 OAP58106.1 - 0.026 13.6 0.1 0.79 8.7 0.0 2.4 3 0 0 3 3 3 0 FAD binding domain Herpes_UL46 PF03387.14 OAP58106.1 - 0.13 11.0 0.0 0.25 10.0 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus UL46 protein Coat_X PF07552.11 OAP58106.1 - 0.22 11.4 0.8 0.35 10.7 0.1 1.7 2 0 0 2 2 2 0 Spore Coat Protein X and V domain FHA PF00498.26 OAP58107.1 - 1.2e-16 60.8 0.0 2.2e-16 59.9 0.0 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 OAP58107.1 - 0.00022 21.5 0.0 0.00057 20.2 0.0 1.7 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain YhfZ_C PF14503.6 OAP58107.1 - 0.005 16.4 0.4 0.0099 15.4 0.0 1.6 2 0 0 2 2 2 1 YhfZ C-terminal domain Tropomyosin_1 PF12718.7 OAP58107.1 - 0.0084 16.3 14.0 0.0084 16.3 14.0 2.7 2 1 0 3 3 3 1 Tropomyosin like Fib_alpha PF08702.10 OAP58107.1 - 0.27 11.4 9.8 0.028 14.6 3.3 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family TolA_bind_tri PF16331.5 OAP58107.1 - 0.39 10.8 13.0 1.4 9.0 4.0 2.8 2 0 0 2 2 2 0 TolA binding protein trimerisation DUF2937 PF11157.8 OAP58107.1 - 2.2 8.0 8.3 0.63 9.7 4.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) XhlA PF10779.9 OAP58107.1 - 5.7 7.2 8.7 0.96 9.7 0.6 2.9 2 1 0 2 2 2 0 Haemolysin XhlA Jnk-SapK_ap_N PF09744.9 OAP58107.1 - 6.4 7.0 27.5 0.92 9.7 13.1 2.5 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DUF2205 PF10224.9 OAP58107.1 - 10 6.2 13.5 4.5 7.3 0.3 3.5 1 1 1 3 3 3 0 Short coiled-coil protein Romo1 PF10247.9 OAP58108.1 - 7.2e-21 74.3 20.7 1.3e-20 73.5 20.7 1.4 1 1 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 SNARE PF05739.19 OAP58109.1 - 5.9e-13 48.6 0.1 1.3e-12 47.5 0.1 1.6 1 0 0 1 1 1 1 SNARE domain Syntaxin-5_N PF11416.8 OAP58109.1 - 2.3e-11 42.6 0.5 5.8e-11 41.3 0.5 1.8 1 0 0 1 1 1 1 Syntaxin-5 N-terminal, Sly1p-binding domain Syntaxin PF00804.25 OAP58109.1 - 2.5e-06 27.3 5.0 5.8e-05 22.8 0.0 2.9 2 1 0 2 2 2 2 Syntaxin KxDL PF10241.9 OAP58109.1 - 0.00014 22.1 2.9 0.1 12.9 0.1 3.3 4 0 0 4 4 4 2 Uncharacterized conserved protein Syntaxin-18_N PF10496.9 OAP58109.1 - 0.0024 18.1 1.9 0.017 15.4 0.0 2.8 2 1 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus NPV_P10 PF05531.12 OAP58109.1 - 0.012 16.1 6.1 0.64 10.5 0.4 3.5 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein BLOC1_2 PF10046.9 OAP58109.1 - 0.71 10.2 3.5 2.1 8.7 0.2 2.9 2 2 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF16 PF01519.16 OAP58109.1 - 0.77 10.3 4.7 0.37 11.3 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function DUF16 Prominin PF05478.11 OAP58109.1 - 5.3 4.9 7.4 2.4 6.0 0.5 2.2 1 1 1 2 2 2 0 Prominin Fes1 PF08609.10 OAP58109.1 - 6.3 7.7 6.5 92 4.0 6.5 2.6 1 1 0 1 1 1 0 Nucleotide exchange factor Fes1 DUF4797 PF16051.5 OAP58111.1 - 0.029 14.3 0.2 0.068 13.1 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4797) Sas10_Utp3 PF04000.15 OAP58112.1 - 2.4e-18 66.5 1.1 2.4e-18 66.5 1.1 1.9 2 0 0 2 2 2 1 Sas10/Utp3/C1D family NPV_P10 PF05531.12 OAP58112.1 - 0.095 13.2 0.8 0.28 11.7 0.2 2.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein ApbA_C PF08546.11 OAP58113.1 - 6.5e-31 107.1 0.0 1e-30 106.5 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 OAP58113.1 - 5.6e-23 81.3 0.0 9e-22 77.4 0.0 2.2 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA DUF3433 PF11915.8 OAP58118.1 - 2.1e-32 111.4 21.5 8.9e-24 83.8 2.6 3.7 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) Virul_fac_BrkB PF03631.15 OAP58118.1 - 0.025 14.2 37.0 0.26 10.9 4.9 4.1 4 0 0 4 4 4 0 Virulence factor BrkB COesterase PF00135.28 OAP58119.1 - 2.4e-09 36.6 0.4 3.9e-09 35.9 0.4 1.3 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAP58119.1 - 2e-07 31.1 0.0 2.6e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 OAP58119.1 - 4.7e-05 22.4 0.1 0.00049 19.1 0.0 2.0 2 0 0 2 2 2 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 OAP58119.1 - 0.018 14.5 0.0 0.033 13.6 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF1749 PF08538.10 OAP58119.1 - 0.064 12.3 0.0 0.23 10.5 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1749) FAD_binding_3 PF01494.19 OAP58120.1 - 2.6e-26 92.7 0.0 5.7e-26 91.6 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAP58120.1 - 1.5e-10 41.2 1.2 8.9e-05 22.2 1.0 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAP58120.1 - 4.4e-08 32.7 0.2 0.00046 19.5 0.2 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAP58120.1 - 3.9e-07 29.1 0.2 8.5e-07 28.0 0.2 1.5 1 1 0 1 1 1 1 HI0933-like protein Trp_halogenase PF04820.14 OAP58120.1 - 8.1e-06 24.9 2.4 0.0064 15.4 1.3 2.2 1 1 1 2 2 2 2 Tryptophan halogenase FAD_binding_2 PF00890.24 OAP58120.1 - 1.4e-05 24.4 2.3 2.5e-05 23.5 2.3 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 OAP58120.1 - 2.9e-05 24.2 2.1 7.3e-05 22.9 2.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 OAP58120.1 - 0.00022 20.4 1.1 0.0016 17.6 1.1 1.9 1 1 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 OAP58120.1 - 0.00058 19.2 0.1 0.3 10.3 0.8 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 OAP58120.1 - 0.00066 19.1 1.6 0.043 13.1 0.0 2.4 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase GIDA PF01134.22 OAP58120.1 - 0.00076 18.7 0.1 0.00087 18.5 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A SE PF08491.10 OAP58120.1 - 0.0012 17.9 0.0 0.0058 15.7 0.0 1.9 1 1 0 1 1 1 1 Squalene epoxidase 3HCDH_N PF02737.18 OAP58120.1 - 0.0023 17.8 0.3 0.0033 17.3 0.3 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.27 OAP58120.1 - 0.0054 17.3 0.1 0.15 12.6 0.1 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 OAP58120.1 - 0.01 15.2 0.5 0.018 14.3 0.5 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 OAP58120.1 - 0.017 14.5 3.0 0.029 13.7 3.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_Gly3P_dh_N PF01210.23 OAP58120.1 - 0.075 13.0 0.1 0.11 12.4 0.1 1.2 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DUF3603 PF12227.8 OAP58120.1 - 0.15 11.3 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3603) Pentapeptide_2 PF01469.18 OAP58121.1 - 0.29 11.0 4.3 0.57 10.1 4.3 1.5 1 0 0 1 1 1 0 Pentapeptide repeats (8 copies) Fig1 PF12351.8 OAP58123.1 - 5.4e-10 39.5 1.2 1.1e-09 38.5 1.2 1.5 1 0 0 1 1 1 1 Ca2+ regulator and membrane fusion protein Fig1 DUF898 PF05987.13 OAP58123.1 - 0.0013 17.9 0.8 0.0018 17.4 0.8 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF898) Choline_transpo PF04515.12 OAP58123.1 - 0.011 15.0 1.8 0.021 14.0 1.8 1.4 1 0 0 1 1 1 0 Plasma-membrane choline transporter SUR7 PF06687.12 OAP58124.1 - 2.5e-19 69.8 12.7 3.1e-19 69.4 12.7 1.1 1 0 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.8 OAP58124.1 - 0.8 9.6 17.1 1.8 8.4 14.7 2.0 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 Sugar_tr PF00083.24 OAP58128.1 - 2e-79 267.6 26.8 2.4e-79 267.3 26.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP58128.1 - 3.3e-30 105.2 25.8 7.8e-28 97.4 21.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily His_Phos_2 PF00328.22 OAP58129.1 - 0.15 11.3 0.0 4.3 6.6 0.0 2.2 2 0 0 2 2 2 0 Histidine phosphatase superfamily (branch 2) Aldedh PF00171.22 OAP58130.1 - 4.3e-154 513.4 0.2 4.9e-154 513.3 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 OAP58130.1 - 0.0039 16.7 0.0 0.012 15.1 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) FMN_dh PF01070.18 OAP58131.1 - 5.6e-102 341.3 0.0 6.6e-102 341.1 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 OAP58131.1 - 0.00021 20.5 0.2 0.00045 19.5 0.2 1.4 2 0 0 2 2 2 1 Conserved region in glutamate synthase IMPDH PF00478.25 OAP58131.1 - 0.00079 18.5 3.2 0.0023 17.0 1.5 2.1 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain Flag1_repress PF03614.13 OAP58131.1 - 0.02 14.7 0.1 0.22 11.3 0.1 2.1 2 0 0 2 2 2 0 Repressor of phase-1 flagellin His_biosynth PF00977.21 OAP58131.1 - 0.13 11.7 0.6 4.1 6.8 0.1 2.3 1 1 1 2 2 2 0 Histidine biosynthesis protein Pkinase PF00069.25 OAP58132.1 - 3.5e-63 213.5 0.0 4.2e-63 213.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP58132.1 - 8.2e-36 123.6 0.0 1.1e-35 123.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAP58132.1 - 9.2e-07 28.5 0.0 1.5e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OAP58132.1 - 0.00043 19.2 0.0 0.00062 18.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 OAP58132.1 - 0.12 11.9 0.0 3.4 7.2 0.0 2.1 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 KH_1 PF00013.29 OAP58133.1 - 2.5e-42 142.5 8.9 1.3e-16 60.1 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 OAP58133.1 - 6.8e-10 38.6 10.6 0.013 15.3 0.5 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 OAP58133.1 - 1.6e-08 34.3 7.3 0.014 15.3 0.4 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 OAP58133.1 - 0.00045 20.3 5.7 0.29 11.2 0.1 3.4 3 0 0 3 3 3 2 NusA-like KH domain MOEP19 PF16005.5 OAP58133.1 - 0.032 14.2 0.0 13 5.9 0.0 2.5 3 0 0 3 3 3 0 KH-like RNA-binding domain ADH_N PF08240.12 OAP58134.1 - 6.1e-30 103.3 0.7 9.7e-30 102.7 0.7 1.2 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAP58134.1 - 2.5e-14 53.4 0.0 3.7e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 OAP58134.1 - 0.065 13.2 1.4 0.097 12.6 0.1 2.0 2 0 0 2 2 2 0 Alcohol dehydrogenase GroES-associated Yippee-Mis18 PF03226.14 OAP58135.1 - 2.4e-19 69.5 0.6 2.8e-19 69.3 0.6 1.0 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.8 OAP58135.1 - 0.0004 20.6 1.6 0.00053 20.2 1.6 1.2 1 0 0 1 1 1 1 C-terminal domain of RIG-I CpXC PF14353.6 OAP58135.1 - 0.039 14.0 0.1 0.11 12.6 0.0 1.7 2 0 0 2 2 2 0 CpXC protein Eapp_C PF10238.9 OAP58135.1 - 0.081 13.0 2.3 1.1 9.3 0.3 2.1 1 1 1 2 2 2 0 E2F-associated phosphoprotein RabGAP-TBC PF00566.18 OAP58137.1 - 4e-34 118.2 0.1 6.4e-34 117.5 0.1 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Retrotrans_gag PF03732.17 OAP58137.1 - 0.034 14.4 0.1 0.067 13.5 0.1 1.5 1 0 0 1 1 1 0 Retrotransposon gag protein Hid1 PF12722.7 OAP58137.1 - 0.91 7.6 2.7 1.5 6.9 2.7 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Pkinase PF00069.25 OAP58138.1 - 1.5e-54 185.1 0.0 2.2e-54 184.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP58138.1 - 2.3e-18 66.4 0.0 3.5e-18 65.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAP58138.1 - 9.3e-06 25.2 0.0 1.8e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 OAP58138.1 - 1.7e-05 24.9 0.3 0.043 13.7 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OAP58138.1 - 0.0033 16.4 0.1 0.0053 15.7 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 OAP58138.1 - 0.0034 17.0 0.0 0.0096 15.5 0.0 1.7 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 OAP58138.1 - 0.0094 14.8 0.0 0.015 14.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Sod_Cu PF00080.20 OAP58138.1 - 0.043 14.0 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 Copper/zinc superoxide dismutase (SODC) LRR_6 PF13516.6 OAP58139.1 - 1.1e-12 46.9 3.2 0.0047 16.9 0.0 6.2 7 0 0 7 7 7 4 Leucine Rich repeat F-box-like PF12937.7 OAP58139.1 - 3.3e-10 39.7 0.2 7.6e-10 38.5 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAP58139.1 - 9e-06 25.4 0.0 3.1e-05 23.7 0.0 1.9 1 0 0 1 1 1 1 F-box domain LRR_4 PF12799.7 OAP58139.1 - 0.0041 17.5 0.1 0.0041 17.5 0.1 5.9 4 2 1 5 5 5 1 Leucine Rich repeats (2 copies) PRANC PF09372.10 OAP58139.1 - 0.074 13.4 0.0 0.24 11.7 0.0 1.9 1 0 0 1 1 1 0 PRANC domain LRR_1 PF00560.33 OAP58139.1 - 0.36 11.6 15.6 1.5 9.6 0.0 6.3 6 1 0 6 6 6 0 Leucine Rich Repeat MBOAT PF03062.19 OAP58141.1 - 5.1e-34 118.2 11.7 8.9e-34 117.4 7.9 2.1 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family Ring_hydroxyl_A PF00848.19 OAP58141.1 - 3.5e-22 79.4 2.3 6.9e-10 39.3 0.0 2.3 1 1 1 2 2 2 2 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.26 OAP58141.1 - 4.4e-14 52.2 0.0 8.7e-14 51.2 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pex14_N PF04695.13 OAP58141.1 - 0.0035 18.0 0.0 0.011 16.3 0.0 1.8 2 0 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region dCMP_cyt_deam_1 PF00383.23 OAP58142.1 - 3.9e-09 36.3 0.1 6.6e-09 35.6 0.1 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 OAP58142.1 - 6.7e-08 32.4 0.0 9.9e-08 31.8 0.0 1.3 1 0 0 1 1 1 1 MafB19-like deaminase SNAD4 PF18750.1 OAP58142.1 - 0.031 14.4 0.3 0.058 13.5 0.3 1.4 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 CMS1 PF14617.6 OAP58143.1 - 5e-52 176.7 0.0 6.4e-52 176.4 0.0 1.1 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.29 OAP58143.1 - 0.0011 18.7 0.0 0.0016 18.2 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase adh_short_C2 PF13561.6 OAP58144.1 - 5.4e-31 108.0 0.1 6.8e-31 107.6 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP58144.1 - 8.7e-26 90.6 0.1 1.1e-25 90.3 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAP58144.1 - 0.00036 20.5 0.2 0.00054 19.9 0.2 1.2 1 0 0 1 1 1 1 KR domain Pyr_redox_2 PF07992.14 OAP58144.1 - 0.0015 17.9 0.1 0.0023 17.2 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 OAP58144.1 - 0.0021 18.5 0.1 0.0059 17.0 0.1 1.7 2 0 0 2 2 2 1 Putative NAD(P)-binding Sacchrp_dh_NADP PF03435.18 OAP58144.1 - 0.0097 16.2 0.1 0.016 15.5 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain 3HCDH_N PF02737.18 OAP58144.1 - 0.012 15.5 0.1 0.021 14.7 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 OAP58144.1 - 0.022 14.1 0.0 0.048 13.0 0.0 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Pyr_redox PF00070.27 OAP58144.1 - 0.022 15.3 0.1 0.047 14.3 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 OAP58144.1 - 0.033 14.4 0.0 0.06 13.6 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain AlaDh_PNT_C PF01262.21 OAP58144.1 - 0.055 12.8 2.8 0.22 10.8 0.2 2.1 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 OAP58144.1 - 0.16 11.2 0.0 0.24 10.6 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Fumble PF03630.14 OAP58145.1 - 8.9e-144 478.7 0.4 1.1e-143 478.3 0.4 1.1 1 0 0 1 1 1 1 Fumble EamA PF00892.20 OAP58147.1 - 1.6e-11 44.6 23.4 2.3e-06 27.8 3.1 2.5 2 0 0 2 2 2 2 EamA-like transporter family Nuc_sug_transp PF04142.15 OAP58147.1 - 3.2e-09 36.4 1.7 6.6e-09 35.4 1.7 1.6 1 1 0 1 1 1 1 Nucleotide-sugar transporter TPT PF03151.16 OAP58147.1 - 7.7e-06 25.5 6.2 1.9e-05 24.2 0.3 2.4 2 1 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.11 OAP58147.1 - 0.00037 19.8 9.7 0.00067 19.0 9.7 1.4 1 0 0 1 1 1 1 UAA transporter family CRT-like PF08627.10 OAP58147.1 - 0.08 11.9 0.2 0.08 11.9 0.2 2.4 2 1 0 2 2 2 0 CRT-like, chloroquine-resistance transporter-like DMT_6 PF04342.12 OAP58147.1 - 0.24 11.6 4.9 3.3 8.0 1.0 2.7 2 0 0 2 2 2 0 Putative member of DMT superfamily (DUF486) p450 PF00067.22 OAP58149.1 - 4.9e-60 203.6 0.0 6.3e-60 203.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Adaptin_N PF01602.20 OAP58150.1 - 5.8e-143 477.2 2.8 7.7e-143 476.8 2.8 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 OAP58150.1 - 1.4e-21 76.9 0.0 3.8e-21 75.5 0.0 1.8 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 OAP58150.1 - 1.7e-08 34.7 5.4 0.00011 22.3 0.0 4.4 2 2 2 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 OAP58150.1 - 2.9e-07 30.8 2.4 0.032 14.6 0.0 4.9 5 1 0 5 5 5 2 HEAT repeats DUF3730 PF12530.8 OAP58150.1 - 6.8e-05 22.5 0.1 0.0031 17.1 0.0 2.7 2 1 1 3 3 3 1 Protein of unknown function (DUF3730) HEAT PF02985.22 OAP58150.1 - 0.0027 17.8 2.1 6.4 7.3 0.1 4.7 5 0 0 5 5 5 1 HEAT repeat HEAT_EZ PF13513.6 OAP58150.1 - 0.02 15.4 0.3 65 4.2 0.0 5.5 5 1 0 5 5 5 0 HEAT-like repeat Arm PF00514.23 OAP58150.1 - 0.052 13.6 0.0 98 3.2 0.1 5.1 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat IFN-gamma PF00714.17 OAP58150.1 - 0.16 11.8 1.0 1.6 8.6 0.3 2.5 2 0 0 2 2 2 0 Interferon gamma DEAD PF00270.29 OAP58151.1 - 1.8e-41 141.8 0.0 3.2e-41 141.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAP58151.1 - 6.2e-29 100.6 0.0 1.5e-28 99.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAP58151.1 - 1.5e-05 25.1 0.0 2.8e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 OAP58151.1 - 0.033 12.9 0.0 0.05 12.3 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain LSDAT_prok PF18171.1 OAP58151.1 - 0.11 11.8 0.0 0.19 10.9 0.0 1.4 1 0 0 1 1 1 0 SLOG in TRPM, prokaryote AAA_22 PF13401.6 OAP58151.1 - 0.11 12.7 0.0 0.66 10.2 0.0 2.3 2 2 0 2 2 2 0 AAA domain Glyco_transf_28 PF03033.20 OAP58152.1 - 2e-21 76.5 0.0 5.5e-21 75.1 0.0 1.8 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 OAP58152.1 - 0.0018 17.2 0.0 0.0027 16.6 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 OAP58152.1 - 0.062 13.3 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain VPS13_C PF16909.5 OAP58152.1 - 0.076 12.8 0.3 0.19 11.5 0.3 1.6 1 0 0 1 1 1 0 Vacuolar-sorting-associated 13 protein C-terminal ATG_C PF09333.11 OAP58152.1 - 0.11 12.9 0.2 0.71 10.3 0.0 2.2 2 0 0 2 2 2 0 Autophagy-related protein C terminal domain Aldo_ket_red PF00248.21 OAP58153.1 - 2.1e-50 171.6 0.0 2.4e-50 171.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family p450 PF00067.22 OAP58154.1 - 1.3e-67 228.6 0.0 1.8e-67 228.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 NAD_binding_3 PF03447.16 OAP58155.1 - 9.1e-06 26.3 0.1 2.6e-05 24.8 0.1 1.8 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain SAF PF08666.12 OAP58155.1 - 1.9e-05 25.2 0.1 6.3e-05 23.5 0.0 2.0 2 0 0 2 2 2 1 SAF domain NmrA PF05368.13 OAP58156.1 - 1e-27 97.2 0.0 4e-27 95.3 0.0 1.8 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.6 OAP58156.1 - 2.1e-06 27.8 0.0 2.7e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding TrkA_N PF02254.18 OAP58156.1 - 0.2 11.9 0.0 0.31 11.3 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain Fungal_trans_2 PF11951.8 OAP58157.1 - 1.1e-18 67.2 2.2 2.3e-18 66.2 2.2 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 OAP58158.1 - 9.4e-38 130.0 33.2 1.2e-37 129.6 33.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily PT-VENN PF04829.13 OAP58158.1 - 0.0077 16.3 1.1 0.025 14.7 1.1 1.8 1 0 0 1 1 1 1 Pre-toxin domain with VENN motif Abhydrolase_1 PF00561.20 OAP58159.1 - 1.9e-14 53.9 0.2 5.5e-12 45.9 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAP58159.1 - 1.1e-06 29.4 0.3 1.5e-06 29.0 0.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAP58159.1 - 7.7e-05 22.1 0.3 0.00061 19.1 0.2 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DAO PF01266.24 OAP58160.1 - 6.2e-14 52.3 0.0 7.5e-14 52.1 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAP58160.1 - 0.00074 18.8 0.0 0.023 14.0 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAP58160.1 - 0.011 15.0 0.0 0.019 14.2 0.0 1.3 1 0 0 1 1 1 0 Thi4 family NAD_binding_8 PF13450.6 OAP58160.1 - 0.015 15.5 0.2 0.053 13.7 0.0 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 OAP58160.1 - 0.043 13.8 0.3 0.094 12.7 0.1 1.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding Mqo PF06039.15 OAP58160.1 - 0.052 12.1 0.0 0.068 11.7 0.0 1.2 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) DUF3425 PF11905.8 OAP58161.1 - 7e-09 35.7 0.0 2e-08 34.3 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 OAP58161.1 - 3 8.0 9.3 5.8 7.1 9.3 1.5 1 0 0 1 1 1 0 bZIP transcription factor Epimerase PF01370.21 OAP58163.1 - 3.6e-10 39.7 0.1 2.2e-05 24.0 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 OAP58163.1 - 6.8e-08 32.6 0.0 9.7e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 OAP58163.1 - 1e-05 25.3 0.1 1.5e-05 24.6 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 OAP58163.1 - 0.0015 17.6 0.0 0.012 14.6 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.18 OAP58163.1 - 0.0016 18.6 0.2 0.0029 17.9 0.2 1.4 1 0 0 1 1 1 1 TrkA-N domain Shikimate_DH PF01488.20 OAP58163.1 - 0.0039 17.2 0.1 0.0072 16.4 0.1 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_2 PF03446.15 OAP58163.1 - 0.025 14.8 0.0 0.041 14.1 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Polysacc_synt_2 PF02719.15 OAP58163.1 - 0.025 13.7 0.0 0.037 13.2 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 OAP58163.1 - 0.054 13.8 0.1 0.14 12.5 0.1 1.7 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain ApbA PF02558.16 OAP58163.1 - 0.055 13.1 0.0 0.088 12.4 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 OAP58163.1 - 0.077 12.9 0.1 0.12 12.2 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 OAP58163.1 - 0.08 12.2 0.1 0.13 11.6 0.1 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain BCDHK_Adom3 PF10436.9 OAP58164.1 - 5.7e-46 156.3 0.0 8.1e-46 155.8 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 OAP58164.1 - 1.5e-10 41.6 0.0 1.5e-09 38.3 0.0 2.5 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 OAP58164.1 - 0.068 13.1 0.0 0.36 10.8 0.0 2.1 1 1 0 1 1 1 0 Histidine kinase-like ATPase domain Carboxyl_trans PF01039.22 OAP58165.1 - 1.7e-67 228.2 0.0 2.9e-67 227.4 0.0 1.3 1 1 0 1 1 1 1 Carboxyl transferase domain E1_dh PF00676.20 OAP58165.1 - 0.23 10.4 0.0 0.36 9.7 0.0 1.2 1 0 0 1 1 1 0 Dehydrogenase E1 component CPSase_L_D2 PF02786.17 OAP58166.1 - 1.6e-52 178.1 0.0 2.9e-52 177.3 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.19 OAP58166.1 - 5.1e-35 119.8 0.0 1.9e-34 118.0 0.0 2.0 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_carb_N PF00289.22 OAP58166.1 - 8.1e-27 93.9 0.0 1.7e-26 92.9 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_lipoyl PF00364.22 OAP58166.1 - 3.9e-13 49.0 3.6 8.8e-13 47.9 2.0 2.4 2 1 0 2 2 2 1 Biotin-requiring enzyme ATP-grasp PF02222.22 OAP58166.1 - 1.4e-06 28.0 0.1 2.6e-06 27.1 0.1 1.4 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 OAP58166.1 - 2.8e-06 27.0 0.0 5e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.6 OAP58166.1 - 8.3e-06 25.5 0.2 0.0056 16.5 0.0 2.5 2 0 0 2 2 2 2 Biotin-lipoyl like RnfC_N PF13375.6 OAP58166.1 - 0.00025 20.9 0.0 0.00085 19.2 0.0 1.9 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain DUF2118 PF09891.9 OAP58166.1 - 0.00029 20.8 0.1 0.00059 19.8 0.1 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2118) ATP-grasp_3 PF02655.14 OAP58166.1 - 0.0011 19.1 0.0 0.0023 18.0 0.0 1.5 1 1 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.6 OAP58166.1 - 0.016 14.9 0.1 0.039 13.7 0.1 1.5 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon ATPgrasp_ST PF14397.6 OAP58166.1 - 0.022 14.0 0.0 0.11 11.8 0.0 1.9 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp PIN_6 PF17146.4 OAP58166.1 - 0.074 13.6 0.1 0.43 11.1 0.0 2.2 2 0 0 2 2 2 0 PIN domain of ribonuclease HMG_box PF00505.19 OAP58167.1 - 5.2e-22 78.1 0.1 9.1e-22 77.3 0.1 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 OAP58167.1 - 1.6e-09 38.3 0.0 3.5e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 HMG-box domain WD40 PF00400.32 OAP58168.1 - 2.1e-49 164.4 30.6 9.1e-08 32.6 0.1 9.1 8 1 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAP58168.1 - 1.3e-11 44.7 0.1 0.045 14.1 0.1 5.5 4 2 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OAP58168.1 - 1.3e-05 24.0 0.5 0.0016 17.2 0.0 3.3 4 0 0 4 4 4 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 OAP58168.1 - 1.5e-05 24.0 0.0 1 8.0 0.0 3.2 3 0 0 3 3 3 3 Nup133 N terminal like bZIP_2 PF07716.15 OAP58168.1 - 0.0062 16.6 0.5 0.013 15.6 0.5 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 OAP58168.1 - 0.14 12.3 0.3 0.31 11.2 0.3 1.5 1 0 0 1 1 1 0 bZIP transcription factor DivIC PF04977.15 OAP58168.1 - 0.23 11.3 0.2 0.39 10.5 0.2 1.3 1 0 0 1 1 1 0 Septum formation initiator CLASP_N PF12348.8 OAP58169.1 - 2.6e-05 23.9 0.2 0.011 15.3 0.0 2.4 2 0 0 2 2 2 2 CLASP N terminal Cnd1 PF12717.7 OAP58169.1 - 7.6e-05 22.8 6.2 0.049 13.7 0.2 3.6 3 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HALZ PF02183.18 OAP58169.1 - 8.3e-05 22.7 6.6 0.11 12.7 0.1 3.1 3 0 0 3 3 3 2 Homeobox associated leucine zipper Adaptin_N PF01602.20 OAP58169.1 - 0.00023 19.9 3.3 0.0023 16.6 3.4 2.4 1 1 1 2 2 2 2 Adaptin N terminal region HEAT PF02985.22 OAP58169.1 - 0.0087 16.2 0.5 11 6.6 0.6 4.5 4 0 0 4 4 4 0 HEAT repeat APG6_N PF17675.1 OAP58169.1 - 0.0094 16.5 10.2 0.0094 16.5 10.2 2.4 2 0 0 2 2 1 1 Apg6 coiled-coil region DivIC PF04977.15 OAP58169.1 - 0.015 15.0 14.4 0.29 10.9 5.2 3.4 2 1 1 3 3 3 0 Septum formation initiator TAN PF11640.8 OAP58169.1 - 0.024 14.8 0.1 0.024 14.8 0.1 2.8 3 1 0 3 3 3 0 Telomere-length maintenance and DNA damage repair Mod_r PF07200.13 OAP58169.1 - 0.029 14.5 8.9 0.24 11.5 7.4 2.7 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Vac14_Fab1_bd PF12755.7 OAP58169.1 - 0.062 13.9 0.0 54 4.5 0.0 3.6 2 1 1 3 3 3 0 Vacuolar 14 Fab1-binding region MMS19_N PF14500.6 OAP58169.1 - 0.12 11.9 0.6 32 4.0 0.1 3.3 2 2 2 4 4 4 0 Dos2-interacting transcription regulator of RNA-Pol-II Golgin_A5 PF09787.9 OAP58169.1 - 0.13 11.7 8.2 0.28 10.6 8.2 1.4 1 0 0 1 1 1 0 Golgin subfamily A member 5 MOR2-PAG1_C PF14225.6 OAP58169.1 - 0.15 11.9 0.0 0.78 9.5 0.0 2.2 2 1 1 3 3 3 0 Cell morphogenesis C-terminal NRBF2 PF08961.10 OAP58169.1 - 0.3 10.7 9.7 0.37 10.4 0.9 2.6 1 1 1 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator bZIP_1 PF00170.21 OAP58169.1 - 0.35 11.0 13.5 0.93 9.6 0.7 3.2 3 0 0 3 3 3 0 bZIP transcription factor ADIP PF11559.8 OAP58169.1 - 1.2 9.3 10.4 3.8 7.6 10.4 1.9 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding TPR_MLP1_2 PF07926.12 OAP58169.1 - 1.2 9.2 17.0 0.16 12.0 11.4 2.5 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Cep57_CLD_2 PF14197.6 OAP58169.1 - 1.5 9.0 15.4 0.38 10.9 7.7 3.1 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 SseC PF04888.12 OAP58169.1 - 4.2 6.9 7.2 2.4 7.6 2.0 2.5 2 0 0 2 2 2 0 Secretion system effector C (SseC) like family TMF_DNA_bd PF12329.8 OAP58169.1 - 6.9 6.7 11.2 3.3 7.8 7.1 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF3106 PF11304.8 OAP58169.1 - 9.7 6.7 8.5 3.4 8.2 0.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3106) Ribosomal_L7Ae PF01248.26 OAP58170.1 - 4.3e-21 74.5 0.6 4.3e-21 74.5 0.6 1.6 2 0 0 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF913 PF06025.12 OAP58171.1 - 3.8e-97 325.6 0.0 3.8e-97 325.6 0.0 6.1 5 1 0 5 5 5 1 Domain of Unknown Function (DUF913) HECT PF00632.25 OAP58171.1 - 5.8e-92 308.4 0.0 1.2e-91 307.5 0.0 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF908 PF06012.12 OAP58171.1 - 3e-70 237.4 0.3 3e-70 237.4 0.3 2.9 3 0 0 3 3 3 1 Domain of Unknown Function (DUF908) UBM PF14377.6 OAP58171.1 - 6.9e-24 82.5 13.4 3.5e-08 32.6 0.9 3.9 3 0 0 3 3 3 3 Ubiquitin binding region An_peroxidase PF03098.15 OAP58172.1 - 8.7e-38 130.2 0.0 1.5e-24 86.5 0.0 3.1 1 1 2 3 3 3 3 Animal haem peroxidase Imm43 PF15570.6 OAP58172.1 - 0.0055 16.7 0.1 0.015 15.3 0.0 1.7 2 0 0 2 2 2 1 Immunity protein 43 Steroid_dh PF02544.16 OAP58173.1 - 7.7e-32 110.4 0.3 1.1e-31 109.9 0.3 1.2 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.13 OAP58173.1 - 0.00014 22.2 0.1 0.00028 21.2 0.1 1.6 1 0 0 1 1 1 1 Phospholipid methyltransferase DUF1295 PF06966.12 OAP58173.1 - 0.013 15.1 0.1 0.02 14.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1295) DUF621 PF04789.15 OAP58173.1 - 0.049 12.8 0.2 0.084 12.0 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF621) Glyco_transf_34 PF05637.12 OAP58174.1 - 2.9e-56 190.9 0.0 4.1e-56 190.4 0.0 1.2 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Peptidase_M20 PF01546.28 OAP58175.1 - 5.5e-31 107.9 0.1 7.7e-31 107.4 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.17 OAP58175.1 - 0.00019 21.2 0.0 0.00036 20.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 M20_dimer PF07687.14 OAP58175.1 - 0.00027 20.8 0.1 0.00068 19.5 0.1 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain ANAPC15 PF15243.6 OAP58175.1 - 0.0076 16.6 0.0 0.014 15.7 0.0 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 15 SET PF00856.28 OAP58176.1 - 0.00043 20.7 0.0 0.00079 19.9 0.0 1.5 1 0 0 1 1 1 1 SET domain DUF5313 PF17240.2 OAP58176.1 - 0.098 13.1 0.1 0.2 12.1 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5313) Complex1_51K PF01512.17 OAP58177.1 - 1.9e-45 154.5 0.0 3e-45 153.8 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 OAP58177.1 - 5.6e-29 100.0 0.4 1.3e-28 98.9 0.4 1.7 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 OAP58177.1 - 7.6e-10 38.5 0.0 3.6e-09 36.3 0.0 2.1 2 0 0 2 2 2 1 SLBB domain DUF3568 PF12092.8 OAP58177.1 - 0.14 12.2 0.2 0.34 11.0 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3568) AP_endonuc_2 PF01261.24 OAP58178.1 - 7.7e-29 100.6 0.2 1.4e-28 99.8 0.1 1.5 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel Inositol_P PF00459.25 OAP58179.1 - 1.5e-74 250.9 0.0 2.7e-74 250.1 0.0 1.5 1 1 0 1 1 1 1 Inositol monophosphatase family Spt20 PF12090.8 OAP58179.1 - 0.37 10.4 7.6 0.62 9.6 7.6 1.4 1 0 0 1 1 1 0 Spt20 family DHquinase_II PF01220.19 OAP58180.1 - 7.5e-54 181.2 0.0 1.6e-53 180.0 0.0 1.5 1 1 0 1 1 1 1 Dehydroquinase class II Sortilin-Vps10 PF15902.5 OAP58180.1 - 0.071 11.9 0.0 0.098 11.4 0.0 1.1 1 0 0 1 1 1 0 Sortilin, neurotensin receptor 3, Med3 PF11593.8 OAP58180.1 - 2.1 7.5 3.5 2.6 7.1 3.5 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Sugar_tr PF00083.24 OAP58181.1 - 8.9e-129 430.3 25.1 1e-128 430.1 25.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP58181.1 - 8.6e-20 70.9 36.3 8.6e-20 70.9 36.3 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Shikimate_dh_N PF08501.11 OAP58182.1 - 1.5e-21 76.4 0.0 2.7e-21 75.6 0.0 1.4 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.20 OAP58182.1 - 0.011 15.8 0.0 0.018 15.1 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase SDH_C PF18317.1 OAP58182.1 - 0.039 13.7 0.0 0.13 12.0 0.0 2.0 2 0 0 2 2 2 0 Shikimate 5'-dehydrogenase C-terminal domain DHquinase_I PF01487.15 OAP58183.1 - 5.1e-21 76.0 0.0 9.2e-21 75.1 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase Shikimate_dh_N PF08501.11 OAP58183.1 - 1e-15 57.7 0.0 2.3e-15 56.6 0.0 1.6 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SKI PF01202.22 OAP58183.1 - 3.8e-15 56.4 0.0 7.6e-15 55.4 0.0 1.5 1 0 0 1 1 1 1 Shikimate kinase Shikimate_DH PF01488.20 OAP58183.1 - 2.2e-07 31.0 0.1 4.5e-07 30.0 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase SDH_C PF18317.1 OAP58183.1 - 1.6e-06 27.7 0.0 3.2e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain F420_oxidored PF03807.17 OAP58183.1 - 0.095 13.3 0.0 0.26 11.9 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Fungal_trans PF04082.18 OAP58184.1 - 1.5e-16 60.3 0.0 2.3e-16 59.7 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP58184.1 - 2.4e-08 34.0 11.9 4.2e-08 33.2 11.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HET PF06985.11 OAP58185.1 - 1.5e-24 87.0 0.0 2.6e-24 86.2 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) F-box-like PF12937.7 OAP58186.1 - 5.6e-06 26.1 0.1 1.7e-05 24.6 0.1 1.9 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.6 OAP58186.1 - 4.2e-05 23.2 5.2 3.3 8.0 0.6 6.0 5 0 0 5 5 5 2 Leucine Rich repeat F-box PF00646.33 OAP58186.1 - 0.0036 17.2 0.3 0.024 14.5 0.3 2.4 1 1 0 1 1 1 1 F-box domain LRR_4 PF12799.7 OAP58186.1 - 0.7 10.4 6.9 7.5 7.1 1.1 4.1 3 1 2 5 5 5 0 Leucine Rich repeats (2 copies) Aminotran_5 PF00266.19 OAP58187.1 - 7e-22 77.9 0.0 2.6e-21 76.0 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 OAP58187.1 - 3.9e-05 23.0 0.0 0.00014 21.2 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class I and II SepSecS PF05889.13 OAP58187.1 - 0.044 12.5 0.0 0.066 11.9 0.0 1.2 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS DegT_DnrJ_EryC1 PF01041.17 OAP58187.1 - 0.14 11.4 0.0 16 4.7 0.0 2.1 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Rieske PF00355.26 OAP58187.1 - 0.18 11.8 0.1 4.7 7.2 0.0 2.2 2 0 0 2 2 2 0 Rieske [2Fe-2S] domain ADH_zinc_N PF00107.26 OAP58188.1 - 6.4e-22 77.9 1.7 7.1e-22 77.8 0.6 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAP58188.1 - 6.6e-11 43.4 0.1 2e-10 41.8 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAP58188.1 - 2.5e-08 33.8 0.0 7e-08 32.3 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 OAP58188.1 - 0.01 15.3 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus NIL PF09383.10 OAP58188.1 - 0.039 13.8 0.0 0.12 12.2 0.0 1.8 2 0 0 2 2 2 0 NIL domain ADH_zinc_N PF00107.26 OAP58192.1 - 3.9e-12 46.3 0.0 7.4e-12 45.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAP58192.1 - 2.9e-06 27.1 0.0 0.00011 22.0 0.0 2.7 3 1 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 OAP58192.1 - 0.003 18.6 0.3 0.12 13.5 0.1 2.9 1 1 1 2 2 2 1 Zinc-binding dehydrogenase adh_short PF00106.25 OAP58192.1 - 0.06 12.8 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase MFS_1 PF07690.16 OAP58193.1 - 0.00061 18.8 10.0 0.0052 15.8 1.6 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Pribosyltran_N PF13793.6 OAP58194.1 - 3.8e-43 146.1 0.2 9.1e-43 144.9 0.1 1.7 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 OAP58194.1 - 2.3e-34 119.1 0.7 2.2e-28 99.5 0.6 2.6 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 OAP58194.1 - 2.8e-16 59.4 0.3 1.4e-15 57.2 0.1 2.0 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 OAP58194.1 - 0.0032 16.9 0.1 0.0064 16.0 0.1 1.5 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Chorismate_bind PF00425.18 OAP58195.1 - 3.5e-88 295.5 0.0 5.3e-88 294.9 0.0 1.3 1 0 0 1 1 1 1 chorismate binding enzyme Ribosomal_S6e PF01092.19 OAP58195.1 - 1.3e-57 193.2 0.0 2.7e-57 192.1 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S6e Anth_synt_I_N PF04715.13 OAP58195.1 - 9.8e-28 97.1 0.0 6.6e-25 88.0 0.0 3.5 3 0 0 3 3 3 1 Anthranilate synthase component I, N terminal region DUF1635 PF07795.11 OAP58196.1 - 0.025 14.4 5.6 0.05 13.5 5.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) Rootletin PF15035.6 OAP58196.1 - 0.037 14.1 11.3 0.068 13.2 11.3 1.4 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DivIC PF04977.15 OAP58196.1 - 0.52 10.1 6.7 0.26 11.1 3.8 2.0 1 1 1 2 2 2 0 Septum formation initiator Herpes_UL6 PF01763.16 OAP58196.1 - 0.84 8.1 6.1 1.3 7.5 5.8 1.4 1 1 0 1 1 1 0 Herpesvirus UL6 like SHE3 PF17078.5 OAP58196.1 - 2.4 7.8 13.0 3.5 7.3 9.6 2.0 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 DUF1664 PF07889.12 OAP58196.1 - 2.9 7.9 11.6 5.1 7.2 1.2 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) TSNAXIP1_N PF15739.5 OAP58196.1 - 3.4 8.1 11.0 0.62 10.5 6.9 1.9 2 0 0 2 2 2 0 Translin-associated factor X-interacting N-terminus Spc7 PF08317.11 OAP58196.1 - 4.1 6.2 21.8 0.82 8.5 14.0 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein ATG16 PF08614.11 OAP58196.1 - 4.2 7.5 18.1 8.5 6.6 17.9 1.6 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) YabA PF06156.13 OAP58196.1 - 4.6 7.9 12.4 0.27 11.9 5.1 2.4 1 1 2 3 3 3 0 Initiation control protein YabA Nup54 PF13874.6 OAP58196.1 - 5.9 7.0 13.7 2.6 8.1 9.4 2.2 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 Ax_dynein_light PF10211.9 OAP58196.1 - 9.8 6.1 16.2 0.72 9.8 8.9 2.2 2 1 0 2 2 2 0 Axonemal dynein light chain WD40 PF00400.32 OAP58197.1 - 2.8e-12 46.9 1.4 0.05 14.5 0.0 6.0 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAP58197.1 - 1.4e-10 41.4 0.0 5.6e-06 26.6 0.0 4.7 4 1 0 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 OAP58197.1 - 3.1e-08 33.3 0.1 1e-07 31.7 0.1 1.9 1 0 0 1 1 1 1 LisH eIF2A PF08662.11 OAP58197.1 - 0.0035 17.2 0.0 0.06 13.2 0.0 2.7 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A DUF1751 PF08551.10 OAP58198.1 - 2.2e-24 85.9 2.5 5e-24 84.7 2.5 1.6 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.22 OAP58198.1 - 4.8e-05 23.4 5.9 4.8e-05 23.4 5.9 1.5 2 0 0 2 2 2 1 Rhomboid family Ribonuclease_T2 PF00445.18 OAP58199.1 - 2e-36 126.0 0.5 3.7e-36 125.1 0.0 1.6 2 0 0 2 2 2 1 Ribonuclease T2 family DUF1330 PF07045.11 OAP58200.1 - 0.0047 17.2 0.0 0.4 11.0 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF1330) ENTH PF01417.20 OAP58201.1 - 3.6e-48 162.7 0.0 5.4e-48 162.2 0.0 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 OAP58201.1 - 0.00037 19.6 0.0 0.00058 18.9 0.0 1.2 1 0 0 1 1 1 1 ANTH domain DUF1720 PF08226.11 OAP58201.1 - 0.0056 17.1 37.7 0.0056 17.1 37.7 5.2 1 1 1 2 2 2 1 Domain of unknown function (DUF1720) DUF4264 PF14084.6 OAP58201.1 - 0.069 12.8 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4264) GPI-anchored PF10342.9 OAP58202.1 - 2e-08 34.9 1.7 2e-08 34.9 1.7 2.0 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Clr5 PF14420.6 OAP58203.1 - 1.6e-09 37.9 0.3 3.1e-09 36.9 0.3 1.5 1 0 0 1 1 1 1 Clr5 domain TPR_12 PF13424.6 OAP58203.1 - 0.13 12.5 0.2 4.4 7.7 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF2673 PF10880.8 OAP58203.1 - 0.2 11.8 0.3 29 4.8 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2673) Clr5 PF14420.6 OAP58204.1 - 2.6e-11 43.5 0.5 7.4e-11 42.1 0.5 1.8 1 0 0 1 1 1 1 Clr5 domain TPR_16 PF13432.6 OAP58204.1 - 0.072 13.7 0.0 0.77 10.5 0.0 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 OAP58204.1 - 0.083 13.0 1.1 7.4 7.0 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Complex1_LYR_2 PF13233.6 OAP58205.1 - 3.7e-22 78.9 0.3 4.6e-22 78.6 0.3 1.1 1 0 0 1 1 1 1 Complex1_LYR-like NAD_binding_2 PF03446.15 OAP58206.1 - 3.4e-25 89.0 0.3 5.5e-25 88.4 0.3 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 OAP58206.1 - 1.4e-19 70.5 0.0 2.5e-19 69.7 0.0 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F-box-like PF12937.7 OAP58207.1 - 0.0009 19.1 0.0 0.0024 17.7 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAP58207.1 - 0.057 13.3 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 F-box domain MutL_C PF08676.11 OAP58208.1 - 1.1e-24 86.9 0.0 2.8e-24 85.5 0.0 1.7 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 OAP58208.1 - 1e-20 73.6 0.0 8.2e-20 70.7 0.0 2.6 4 0 0 4 4 4 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 OAP58208.1 - 4.1e-11 42.9 0.0 1.8e-10 40.8 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 OAP58208.1 - 1.8e-05 25.2 0.0 4.5e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Carn_acyltransf PF00755.20 OAP58209.1 - 6.1e-200 665.8 0.1 7e-200 665.6 0.1 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase DUF2034 PF10356.9 OAP58210.1 - 6.2e-26 91.0 0.0 3.1e-21 75.6 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2034) Mrr_cat PF04471.12 OAP58210.1 - 8e-07 29.1 0.2 0.00012 22.1 0.1 2.9 2 1 0 2 2 2 1 Restriction endonuclease DUF4253 PF14062.6 OAP58210.1 - 0.14 12.3 0.0 0.24 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4253) DUF3237 PF11578.8 OAP58211.1 - 3.9e-17 62.5 0.0 4.8e-17 62.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) CBS PF00571.28 OAP58213.1 - 0.0065 16.9 1.8 0.86 10.1 0.1 3.0 3 0 0 3 3 3 2 CBS domain Glyco_hydro_2 PF00703.21 OAP58214.1 - 6e-10 39.8 0.0 1.2e-09 38.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Mannosidase_ig PF17786.1 OAP58214.1 - 1.2e-09 38.6 0.0 3.2e-09 37.3 0.0 1.8 1 0 0 1 1 1 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2_N PF02837.18 OAP58214.1 - 0.0072 16.2 0.0 0.023 14.6 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.17 OAP58214.1 - 0.0098 15.0 0.2 0.024 13.7 0.2 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain MFS_1 PF07690.16 OAP58215.1 - 1.2e-24 86.9 35.3 1.8e-24 86.4 35.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Cytidylate_kin PF02224.18 OAP58215.1 - 0.18 11.5 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase Peptidase_S9_N PF02897.15 OAP58216.1 - 1e-42 146.5 0.0 1.5e-42 145.9 0.0 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 OAP58216.1 - 4.3e-35 121.1 0.0 7e-35 120.4 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 OAP58216.1 - 5.6e-09 35.6 0.1 5.9e-08 32.3 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OAP58216.1 - 0.00021 21.0 0.1 0.00056 19.6 0.1 1.8 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 OAP58216.1 - 0.031 13.9 0.0 0.056 13.1 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Ribosomal_S7 PF00177.21 OAP58217.1 - 1e-30 106.4 0.0 1.8e-30 105.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e DUF2285 PF10074.9 OAP58217.1 - 0.041 14.5 2.3 0.12 13.0 2.3 1.8 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2285) SOG2 PF10428.9 OAP58217.1 - 0.96 8.6 3.8 1.4 8.1 3.8 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DUF1687 PF07955.11 OAP58217.1 - 1.3 9.5 4.1 3.3 8.2 4.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1687) Na_Ca_ex PF01699.24 OAP58218.1 - 9.7e-46 155.5 36.4 1.8e-24 86.4 16.3 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF420 PF04238.12 OAP58218.1 - 6.3 7.1 14.9 0.19 12.0 1.2 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF420) Dynactin PF12455.8 OAP58219.1 - 9.3e-74 248.2 8.7 9.3e-74 248.2 8.7 4.4 4 3 2 6 6 6 1 Dynein associated protein CAP_GLY PF01302.25 OAP58219.1 - 1.3e-22 79.5 0.3 2.4e-22 78.7 0.3 1.4 1 0 0 1 1 1 1 CAP-Gly domain TSC22 PF01166.18 OAP58219.1 - 0.1 12.9 0.0 0.1 12.9 0.0 9.1 8 2 0 8 8 8 0 TSC-22/dip/bun family KH_1 PF00013.29 OAP58220.1 - 4.9e-37 125.6 4.1 2.6e-07 30.4 0.0 7.4 7 0 0 7 7 7 7 KH domain Diphthamide_syn PF01866.17 OAP58220.1 - 0.031 13.7 0.3 1.2 8.5 0.1 2.2 2 0 0 2 2 2 0 Putative diphthamide synthesis protein SUV3_C PF12513.8 OAP58220.1 - 0.046 13.7 0.0 0.12 12.3 0.0 1.8 1 0 0 1 1 1 0 Mitochondrial degradasome RNA helicase subunit C terminal DUF4210 PF13915.6 OAP58221.1 - 6.6e-32 109.9 0.1 1.3e-31 109.0 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.6 OAP58221.1 - 1.1e-23 83.1 1.2 2.5e-23 82.0 0.2 2.2 2 0 0 2 2 2 1 Chromosome segregation during meiosis TOBE PF03459.17 OAP58222.1 - 0.11 12.8 0.1 0.2 12.0 0.1 1.4 1 0 0 1 1 1 0 TOBE domain rRNA_processing PF08524.11 OAP58222.1 - 2.1 8.4 25.6 27 4.7 25.6 2.1 1 1 0 1 1 1 0 rRNA processing Actin PF00022.19 OAP58223.1 - 2.1e-129 431.7 0.0 2.4e-129 431.5 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.13 OAP58223.1 - 0.13 11.1 0.0 7.1 5.4 0.0 2.2 2 0 0 2 2 2 0 MreB/Mbl protein 5HT_transport_N PF03491.13 OAP58223.1 - 0.18 12.0 0.1 0.43 10.8 0.1 1.6 1 0 0 1 1 1 0 Serotonin (5-HT) neurotransmitter transporter, N-terminus Methyltransf_23 PF13489.6 OAP58224.1 - 2.3e-15 56.8 0.0 5.2e-15 55.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAP58224.1 - 2.1e-07 31.5 0.0 4.7e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAP58224.1 - 6.1e-05 22.9 0.0 0.00024 20.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAP58224.1 - 0.0048 17.6 0.0 0.024 15.4 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAP58224.1 - 0.017 15.7 0.0 0.037 14.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 OAP58224.1 - 0.03 13.9 0.0 0.079 12.5 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase small domain FtsJ PF01728.19 OAP58224.1 - 0.11 12.6 0.0 0.18 11.9 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase Rax2 PF12768.7 OAP58225.1 - 5.9e-65 218.7 1.6 4.5e-63 212.6 0.0 4.0 6 0 0 6 6 6 1 Cortical protein marker for cell polarity DUF5122 PF17164.4 OAP58225.1 - 0.5 10.7 12.6 18 5.7 0.8 6.0 4 0 0 4 4 4 0 Domain of unknown function (DUF5122) beta-propeller OGG_N PF07934.12 OAP58226.1 - 2e-31 108.6 0.0 3.7e-31 107.7 0.0 1.5 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 OAP58226.1 - 8.9e-17 61.5 0.0 1.8e-16 60.5 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 OAP58226.1 - 0.0036 17.1 0.0 0.0085 15.9 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif AA_permease_2 PF13520.6 OAP58227.1 - 1.3e-48 165.9 45.6 1.6e-48 165.6 45.6 1.0 1 0 0 1 1 1 1 Amino acid permease Fungal_trans_2 PF11951.8 OAP58228.1 - 3.4e-36 124.9 1.1 1.2e-35 123.1 1.1 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP58228.1 - 4.2e-05 23.6 7.9 8e-05 22.7 7.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_M20 PF01546.28 OAP58229.1 - 3.5e-30 105.3 0.0 6.1e-30 104.5 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 OAP58229.1 - 1.8e-13 50.3 0.0 3.7e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain RRM_1 PF00076.22 OAP58230.1 - 2.1e-33 114.0 0.1 4.5e-14 52.0 0.0 3.6 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OAP58230.1 - 3.6e-08 33.1 0.0 0.01 15.6 0.0 3.3 3 0 0 3 3 3 2 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 OAP58230.1 - 0.011 15.7 0.0 1.5 8.9 0.0 2.5 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.13 OAP58230.1 - 0.019 14.9 0.0 2.8 8.0 0.0 2.5 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif SKG6 PF08693.10 OAP58230.1 - 5.2 6.6 5.8 12 5.4 5.8 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain GTP_EFTU PF00009.27 OAP58231.1 - 6.1e-41 140.1 0.0 9.5e-41 139.5 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 OAP58231.1 - 3.8e-30 104.5 0.1 1.7e-29 102.4 0.1 2.2 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 OAP58231.1 - 2.7e-05 24.5 0.1 6e-05 23.4 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 OAP58231.1 - 0.00018 21.5 0.1 0.0017 18.5 0.1 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase Ran-binding PF05508.11 OAP58232.1 - 1.8e-123 411.5 0.3 2.2e-123 411.2 0.3 1.1 1 0 0 1 1 1 1 RanGTP-binding protein CorA PF01544.18 OAP58232.1 - 0.019 14.3 2.4 0.035 13.4 2.4 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Tektin PF03148.14 OAP58232.1 - 0.051 12.3 1.6 0.1 11.3 1.6 1.5 1 0 0 1 1 1 0 Tektin family CSTF2_hinge PF14327.6 OAP58233.1 - 1.4e-31 108.7 2.4 1.4e-31 108.7 2.4 2.8 3 0 0 3 3 3 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.22 OAP58233.1 - 8e-20 70.4 0.2 1.3e-19 69.8 0.2 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.6 OAP58233.1 - 3.7e-09 36.0 4.6 3.7e-09 36.0 4.6 2.7 2 0 0 2 2 2 1 Transcription termination and cleavage factor C-terminal RRM_7 PF16367.5 OAP58233.1 - 0.0014 18.7 0.4 0.11 12.7 0.0 2.4 1 1 1 2 2 2 1 RNA recognition motif RRM_occluded PF16842.5 OAP58233.1 - 0.043 13.7 0.0 0.11 12.4 0.0 1.7 1 1 0 1 1 1 0 Occluded RNA-recognition motif Band_7 PF01145.25 OAP58234.1 - 9.8e-23 81.1 5.7 1.8e-22 80.2 5.7 1.5 1 1 0 1 1 1 1 SPFH domain / Band 7 family Methyltransf_5 PF01795.19 OAP58234.1 - 0.14 11.7 3.0 0.22 11.0 3.0 1.3 1 1 0 1 1 1 0 MraW methylase family SNF2_N PF00176.23 OAP58235.1 - 2e-20 72.8 0.1 3.6e-19 68.7 0.1 2.3 1 1 0 1 1 1 1 SNF2 family N-terminal domain DNA_methylase PF00145.17 OAP58235.1 - 4.4e-12 46.0 0.0 9.2e-12 44.9 0.0 1.5 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase ResIII PF04851.15 OAP58235.1 - 0.13 12.2 0.0 0.35 10.9 0.0 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit ACC_central PF08326.12 OAP58236.1 - 1.6e-281 935.9 0.0 2.1e-281 935.5 0.0 1.2 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.22 OAP58236.1 - 2.1e-187 623.7 0.0 3.5e-187 622.9 0.0 1.4 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 OAP58236.1 - 1.2e-52 178.4 0.0 2.4e-52 177.5 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 OAP58236.1 - 3.5e-28 98.4 0.1 7.3e-28 97.3 0.1 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 OAP58236.1 - 2.8e-24 85.3 0.0 2e-21 76.1 0.0 3.3 3 0 0 3 3 3 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 OAP58236.1 - 8.3e-17 60.8 0.2 2e-16 59.6 0.2 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_3 PF02655.14 OAP58236.1 - 0.0037 17.3 0.0 0.012 15.7 0.0 1.8 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 OAP58236.1 - 0.0047 16.5 0.0 0.011 15.3 0.0 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus GxGYxYP_N PF16216.5 OAP58236.1 - 0.015 15.4 0.0 0.034 14.3 0.0 1.5 1 0 0 1 1 1 0 GxGYxY sequence motif in domain of unknown function N-terminal ATP-grasp PF02222.22 OAP58236.1 - 0.03 13.9 0.0 0.07 12.7 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 OAP58236.1 - 0.045 13.6 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Biotin-lipoyl like ATPgrasp_Ter PF15632.6 OAP58236.1 - 0.077 12.7 0.0 0.21 11.3 0.0 1.7 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon SnoaL_2 PF12680.7 OAP58237.1 - 0.00098 19.7 0.0 0.002 18.8 0.0 1.7 1 1 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 OAP58237.1 - 0.016 15.6 0.0 0.027 14.9 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4440) RNA_pol_Rpb2_6 PF00562.28 OAP58238.1 - 1.8e-115 386.1 0.0 2.4e-115 385.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 OAP58238.1 - 3.2e-39 134.6 0.0 6.5e-39 133.6 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 OAP58238.1 - 8.5e-29 99.5 0.0 1.9e-28 98.4 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_2 PF04561.14 OAP58238.1 - 4.1e-24 85.3 0.0 7.2e-24 84.5 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpa2_4 PF06883.12 OAP58238.1 - 6.3e-24 83.7 0.0 1.5e-23 82.5 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_7 PF04560.20 OAP58238.1 - 2.1e-15 56.9 0.0 6.8e-15 55.3 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 PseudoU_synth_1 PF01416.20 OAP58240.1 - 3.8e-09 37.0 0.0 1.3e-07 32.1 0.0 2.4 2 0 0 2 2 2 1 tRNA pseudouridine synthase Catalase-rel PF06628.12 OAP58240.1 - 0.069 13.4 0.7 0.57 10.4 0.4 2.3 2 0 0 2 2 2 0 Catalase-related immune-responsive DUF4441 PF14536.6 OAP58240.1 - 0.18 12.0 0.8 0.38 11.0 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4441) DeoC PF01791.9 OAP58241.1 - 4.1e-11 42.9 1.6 5.4e-11 42.6 1.6 1.1 1 0 0 1 1 1 1 DeoC/LacD family aldolase MOSC PF03473.17 OAP58242.1 - 6.2e-29 100.7 0.0 9.1e-29 100.1 0.0 1.3 1 0 0 1 1 1 1 MOSC domain zf-C3HC4 PF00097.25 OAP58243.1 - 1.2 9.0 7.1 51 3.9 7.1 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_clus PF00172.18 OAP58244.1 - 1.2e-09 38.1 11.3 2e-09 37.4 11.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DIOX_N PF14226.6 OAP58245.1 - 4.2e-26 92.0 0.0 7e-26 91.3 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OAP58245.1 - 6.3e-21 74.8 0.4 2e-20 73.2 0.0 2.0 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily CMD PF02627.20 OAP58246.1 - 2.4e-08 33.9 0.1 1.8e-05 24.7 0.0 2.3 1 1 1 2 2 2 2 Carboxymuconolactone decarboxylase family LAMTOR PF15454.6 OAP58248.1 - 5.5e-10 39.7 0.0 1.1e-09 38.8 0.0 1.5 1 1 0 1 1 1 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator G10 PF01125.17 OAP58249.1 - 0.03 14.1 0.8 0.057 13.2 0.8 1.3 1 0 0 1 1 1 0 G10 protein AMP-binding PF00501.28 OAP58250.1 - 6.2e-53 179.9 0.0 7.8e-53 179.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAP58250.1 - 4.4e-11 43.6 0.0 1.3e-10 42.1 0.0 1.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACOX PF01756.19 OAP58251.1 - 6.6e-41 139.8 0.1 1.6e-40 138.6 0.1 1.7 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 OAP58251.1 - 1.4e-26 93.5 1.0 2.5e-26 92.7 0.3 1.8 2 0 0 2 2 2 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 OAP58251.1 - 3.7e-09 36.7 0.0 9.1e-09 35.4 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 OAP58251.1 - 0.1 12.8 1.6 1.4 9.1 1.6 2.2 1 1 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain ECH_1 PF00378.20 OAP58252.1 - 1.6e-26 93.2 0.0 2e-26 92.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAP58252.1 - 2.1e-11 43.9 0.0 2.4e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase MFS_1 PF07690.16 OAP58253.1 - 3.4e-40 138.0 50.7 3.4e-40 138.0 50.7 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAP58253.1 - 1.6e-13 50.3 13.1 1.6e-13 50.3 13.1 3.0 3 0 0 3 3 3 2 Sugar (and other) transporter NDUF_B12 PF08122.12 OAP58253.1 - 0.21 11.7 1.6 0.52 10.4 0.2 2.5 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B12 subunit family Peptidase_M24 PF00557.24 OAP58254.1 - 4.6e-53 180.0 0.0 7.8e-53 179.3 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 OAP58254.1 - 4e-39 133.1 0.0 7.1e-39 132.3 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Pyridox_ox_2 PF12900.7 OAP58255.1 - 9.6e-39 132.6 0.0 1.3e-38 132.2 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Csa1 PF06023.12 OAP58256.1 - 0.12 11.7 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 CRISPR-associated exonuclease Csa1 Cellulase PF00150.18 OAP58257.1 - 4.2e-13 49.4 0.2 9.6e-13 48.2 0.2 1.5 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF5542 PF17696.1 OAP58257.1 - 0.0012 18.9 0.2 0.0012 18.9 0.2 2.2 2 1 1 3 3 3 1 Family of unknown function (DUF5542) SDA1 PF05285.12 OAP58257.1 - 0.0015 18.1 12.5 0.0023 17.4 12.5 1.2 1 0 0 1 1 1 1 SDA1 DUF4407 PF14362.6 OAP58257.1 - 0.0098 15.3 0.6 0.017 14.5 0.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) TMEM154 PF15102.6 OAP58257.1 - 0.11 12.4 0.1 0.34 10.8 0.0 1.8 2 0 0 2 2 2 0 TMEM154 protein family FAD_binding_9 PF08021.11 OAP58257.1 - 0.13 12.5 0.0 0.86 9.8 0.0 2.1 2 0 0 2 2 2 0 Siderophore-interacting FAD-binding domain Cytomega_UL20A PF05984.12 OAP58257.1 - 0.26 11.6 4.1 0.17 12.2 1.8 1.8 2 0 0 2 2 2 0 Cytomegalovirus UL20A protein DUF1980 PF09323.10 OAP58257.1 - 0.3 11.0 0.0 0.3 11.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) TAF1D PF15333.6 OAP58257.1 - 0.56 9.9 10.7 1.2 8.8 10.7 1.5 1 0 0 1 1 1 0 TATA box-binding protein-associated factor 1D Coiled-coil_56 PF09813.9 OAP58257.1 - 1.9 8.6 6.9 4.8 7.3 6.9 1.6 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 56 SurA_N_2 PF13623.6 OAP58257.1 - 9.7 6.1 7.0 11 5.8 0.1 2.4 2 0 0 2 2 2 0 SurA N-terminal domain APG12 PF04110.13 OAP58260.1 - 8.7e-29 99.8 0.0 1.2e-28 99.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.16 OAP58260.1 - 0.0053 16.9 0.0 0.007 16.5 0.0 1.3 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like Pantoate_transf PF02548.15 OAP58261.1 - 7.2e-106 353.3 0.3 8.7e-106 353.0 0.3 1.1 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 OAP58261.1 - 2.5e-08 33.7 0.5 8.9e-08 31.9 0.2 1.8 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase 4HFCP_synth PF04476.13 OAP58261.1 - 0.039 13.7 0.1 0.062 13.0 0.1 1.3 1 0 0 1 1 1 0 4-HFC-P synthase DUF2012 PF09430.10 OAP58261.1 - 0.12 12.6 0.0 0.25 11.4 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2012) UQ_con PF00179.26 OAP58262.1 - 6.1e-38 129.6 0.1 7.5e-38 129.3 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 OAP58262.1 - 0.046 14.0 0.1 0.091 13.1 0.0 1.6 2 0 0 2 2 2 0 RWD domain F-box PF00646.33 OAP58263.1 - 7.5e-08 32.1 3.2 7.5e-08 32.1 3.2 2.0 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 OAP58263.1 - 1.5e-07 31.1 3.2 3.2e-07 30.1 3.2 1.5 1 0 0 1 1 1 1 F-box-like RPEL PF02755.15 OAP58263.1 - 1.5e-06 27.7 3.4 0.00023 20.8 0.0 3.4 3 0 0 3 3 3 2 RPEL repeat F-box_4 PF15966.5 OAP58263.1 - 0.0015 18.4 1.8 0.0041 17.0 0.8 2.1 2 0 0 2 2 2 1 F-box HemY_N PF07219.13 OAP58263.1 - 0.018 15.2 0.1 0.039 14.2 0.1 1.6 1 0 0 1 1 1 0 HemY protein N-terminus PknG_rubred PF16919.5 OAP58263.1 - 0.19 11.9 1.2 0.48 10.6 1.2 1.7 1 1 0 1 1 1 0 Protein kinase G rubredoxin domain zf-C2H2_2 PF12756.7 OAP58264.1 - 1e-23 83.6 0.4 1e-23 83.6 0.4 1.8 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 OAP58264.1 - 0.015 16.1 5.7 2.5 9.2 0.1 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger Astro_capsid_p PF12226.8 OAP58264.1 - 0.14 11.2 8.4 0.23 10.6 8.4 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein zf-C2H2 PF00096.26 OAP58264.1 - 0.84 10.2 10.4 1.5 9.4 0.2 3.3 3 0 0 3 3 3 0 Zinc finger, C2H2 type DUF1298 PF06974.13 OAP58265.1 - 0.12 12.4 0.1 0.22 11.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1298) SNF2_N PF00176.23 OAP58266.1 - 3.9e-66 223.2 0.2 7.8e-65 218.9 0.2 2.7 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OAP58266.1 - 1.4e-14 54.4 0.0 5.6e-14 52.4 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAP58266.1 - 4.7e-10 39.7 0.2 3.9e-09 36.7 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit THUMP PF02926.17 OAP58266.1 - 0.23 11.6 2.5 0.3 11.2 0.3 2.2 2 0 0 2 2 2 0 THUMP domain TFIIA PF03153.13 OAP58266.1 - 9.6 6.1 27.6 7.8 6.4 15.6 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Pkinase PF00069.25 OAP58267.1 - 1.7e-63 214.4 0.0 2.4e-63 214.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP58267.1 - 1.3e-35 122.9 0.0 1.8e-35 122.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAP58267.1 - 2.4e-05 23.8 0.0 3.6e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 OAP58267.1 - 0.00044 20.3 0.2 0.00044 20.3 0.2 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 OAP58267.1 - 0.00074 18.9 0.4 0.0015 17.9 0.4 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OAP58267.1 - 0.0064 15.5 0.0 0.0087 15.0 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 OAP58267.1 - 0.028 13.2 0.0 0.042 12.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Endonuc_Holl PF10107.9 OAP58267.1 - 0.034 14.0 0.1 0.4 10.5 0.0 2.1 2 0 0 2 2 2 0 Endonuclease related to archaeal Holliday junction resolvase Dfp1_Him1_M PF08630.10 OAP58268.1 - 1.3e-32 112.6 2.4 1.8e-32 112.3 0.0 2.4 3 0 0 3 3 3 1 Dfp1/Him1, central region zf-DBF PF07535.12 OAP58268.1 - 1.7e-21 76.0 0.4 4.7e-21 74.6 0.1 2.0 2 0 0 2 2 2 1 DBF zinc finger PTCB-BRCT PF12738.7 OAP58268.1 - 0.024 14.6 0.0 0.05 13.6 0.0 1.5 1 0 0 1 1 1 0 twin BRCT domain Osteoregulin PF07175.11 OAP58268.1 - 0.41 10.8 7.7 0.22 11.7 4.5 2.2 2 0 0 2 2 2 0 Osteoregulin GTA_holin_3TM PF11351.8 OAP58268.1 - 5.2 7.6 7.9 0.43 11.1 2.4 1.9 2 0 0 2 2 2 0 Holin of 3TMs, for gene-transfer release Pkinase PF00069.25 OAP58269.1 - 5.4e-16 58.7 0.0 3.4e-15 56.1 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP58269.1 - 2.8e-08 33.4 0.0 1.4e-06 27.8 0.0 2.8 1 1 0 1 1 1 1 Protein tyrosine kinase UCH_C PF18031.1 OAP58269.1 - 0.059 13.3 0.4 0.19 11.7 0.0 2.0 2 0 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolases Ribosomal_L6 PF00347.23 OAP58270.1 - 1.8e-21 76.6 0.0 1.3e-10 41.8 0.0 2.5 2 1 0 2 2 2 2 Ribosomal protein L6 Inositol_P PF00459.25 OAP58271.1 - 1.1e-51 176.0 2.4 3.9e-51 174.2 2.4 1.7 1 1 0 1 1 1 1 Inositol monophosphatase family VHS PF00790.19 OAP58272.1 - 3.4e-18 65.9 0.0 7.5e-18 64.7 0.0 1.6 1 0 0 1 1 1 1 VHS domain GAT PF03127.14 OAP58272.1 - 8.9e-06 25.9 0.5 7.7e-05 22.9 0.1 2.6 2 1 1 3 3 3 1 GAT domain ENTH PF01417.20 OAP58272.1 - 0.00073 19.6 0.0 0.0042 17.1 0.0 2.1 1 1 1 2 2 2 1 ENTH domain SnoaL_2 PF12680.7 OAP58273.1 - 0.0011 19.6 0.1 0.0017 18.9 0.1 1.3 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_4 PF13577.6 OAP58273.1 - 0.076 13.1 0.0 0.091 12.9 0.0 1.4 1 1 0 1 1 1 0 SnoaL-like domain FAD_binding_3 PF01494.19 OAP58274.1 - 1.7e-17 63.7 0.0 4e-08 32.9 0.0 2.8 2 1 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 OAP58274.1 - 5.1e-08 32.5 0.0 2.3e-06 27.0 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAP58274.1 - 2.3e-07 30.7 4.4 1.6e-06 28.0 3.8 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OAP58274.1 - 3.3e-07 29.7 4.0 5.5e-07 29.0 4.0 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 OAP58274.1 - 3.9e-06 26.5 2.3 5.6e-06 26.0 2.3 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 OAP58274.1 - 4e-06 27.3 0.1 9.6e-06 26.1 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAP58274.1 - 9.2e-06 25.8 1.1 2e-05 24.7 1.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 OAP58274.1 - 9.2e-06 24.8 0.0 6.1e-05 22.0 0.0 1.9 2 0 0 2 2 2 1 Tryptophan halogenase HI0933_like PF03486.14 OAP58274.1 - 0.00025 19.9 0.1 0.00059 18.7 0.2 1.5 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 OAP58274.1 - 0.0008 18.6 2.2 0.0013 17.9 2.2 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.17 OAP58274.1 - 0.0031 16.8 0.2 0.005 16.1 0.2 1.3 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 OAP58274.1 - 0.0073 15.4 0.7 0.033 13.2 1.0 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein Amino_oxidase PF01593.24 OAP58274.1 - 0.018 14.3 0.3 0.043 13.1 0.2 1.7 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 OAP58274.1 - 0.029 13.6 0.1 0.042 13.1 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 OAP58274.1 - 0.035 13.4 2.7 0.068 12.5 2.7 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 OAP58274.1 - 0.077 13.3 0.1 0.14 12.4 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain CUE PF02845.16 OAP58275.1 - 0.00011 21.8 0.0 0.00022 20.8 0.0 1.5 1 0 0 1 1 1 1 CUE domain Smr PF01713.21 OAP58275.1 - 0.0027 18.0 0.1 0.011 16.0 0.1 2.1 1 1 0 1 1 1 1 Smr domain DUF1771 PF08590.10 OAP58275.1 - 0.003 17.9 9.4 0.0092 16.3 9.4 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) SelR PF01641.18 OAP58276.1 - 3.3e-51 172.5 0.3 3.8e-51 172.2 0.3 1.0 1 0 0 1 1 1 1 SelR domain zinc_ribbon_10 PF10058.9 OAP58276.1 - 0.003 17.3 0.1 0.2 11.4 0.0 2.3 2 0 0 2 2 2 1 Predicted integral membrane zinc-ribbon metal-binding protein Tnp_zf-ribbon_2 PF13842.6 OAP58276.1 - 0.014 16.2 0.2 9.9 7.1 0.1 2.4 2 0 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon Yippee-Mis18 PF03226.14 OAP58276.1 - 0.023 14.9 0.5 0.054 13.7 0.5 1.6 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly TF_Zn_Ribbon PF08271.12 OAP58276.1 - 0.024 14.1 0.8 0.9 9.1 0.1 2.5 2 0 0 2 2 2 0 TFIIB zinc-binding MCM_OB PF17207.3 OAP58276.1 - 0.042 13.7 0.2 0.11 12.4 0.0 1.7 2 0 0 2 2 2 0 MCM OB domain DZR PF12773.7 OAP58276.1 - 0.084 12.9 4.5 1.5 8.9 4.7 2.3 1 1 1 2 2 2 0 Double zinc ribbon Ribosomal_L37e PF01907.19 OAP58276.1 - 0.26 11.5 4.3 4.5 7.5 0.4 2.3 2 0 0 2 2 2 0 Ribosomal protein L37e zf-Mss51 PF13824.6 OAP58276.1 - 0.71 10.0 4.6 8.2 6.6 1.2 3.3 2 1 1 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-ribbon_3 PF13248.6 OAP58276.1 - 2.4 7.7 6.1 2.4 7.7 0.1 3.1 4 0 0 4 4 4 0 zinc-ribbon domain MFS_1 PF07690.16 OAP58277.1 - 1.9e-31 109.3 32.2 2.8e-31 108.8 32.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily QRPTase_C PF01729.19 OAP58278.1 - 1.1e-53 181.5 0.0 1.3e-53 181.2 0.0 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 OAP58278.1 - 3.9e-17 62.1 0.0 1.7e-16 60.0 0.0 2.1 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain PRAI PF00697.22 OAP58278.1 - 0.016 14.9 0.0 0.026 14.3 0.0 1.2 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase AIRC PF00731.20 OAP58279.1 - 7.2e-57 191.1 1.6 8.9e-57 190.8 1.6 1.0 1 0 0 1 1 1 1 AIR carboxylase Fungal_trans PF04082.18 OAP58280.1 - 2.3e-28 99.0 3.7 5.9e-28 97.6 3.2 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 OAP58280.1 - 4.9e-08 33.0 9.2 0.00054 20.3 0.8 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAP58280.1 - 9.5e-06 26.0 6.7 0.042 14.7 0.3 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OAP58280.1 - 2.8 8.6 15.6 1.2 9.7 2.8 3.3 3 0 0 3 3 3 0 Zinc-finger double domain Abhydrolase_6 PF12697.7 OAP58281.1 - 8.3e-10 39.6 23.8 9.1e-08 33.0 23.8 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAP58281.1 - 2e-06 27.6 0.4 2.1e-05 24.3 0.4 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF1688 PF07958.11 OAP58282.1 - 6.4e-150 499.5 0.0 7.2e-150 499.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) DUF2066 PF09839.9 OAP58282.1 - 0.068 12.6 0.3 0.82 9.0 0.2 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2066) GFO_IDH_MocA PF01408.22 OAP58283.1 - 3.6e-17 63.3 0.0 8.9e-17 62.0 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 OAP58283.1 - 0.017 15.8 0.5 0.13 12.9 0.4 2.1 2 0 0 2 2 2 0 Homoserine dehydrogenase, NAD binding domain Pribosyltran_N PF13793.6 OAP58285.1 - 4.1e-44 149.2 0.3 1.1e-42 144.6 0.0 2.2 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 OAP58285.1 - 6.2e-35 120.9 5.6 8.9e-31 107.3 0.7 2.5 2 1 1 3 3 3 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 OAP58285.1 - 5.9e-16 58.4 1.8 1.3e-15 57.3 1.5 1.7 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 OAP58285.1 - 0.027 13.9 0.2 0.072 12.5 0.2 1.7 2 0 0 2 2 2 0 Uracil phosphoribosyltransferase AA_permease_2 PF13520.6 OAP58286.1 - 2e-56 191.6 26.0 1.4e-55 188.9 26.0 1.9 1 1 0 1 1 1 1 Amino acid permease Ank_4 PF13637.6 OAP58288.1 - 2.2e-33 114.2 8.3 9.8e-13 48.3 0.0 6.5 2 1 5 7 7 7 7 Ankyrin repeats (many copies) Ank_2 PF12796.7 OAP58288.1 - 3.3e-31 107.7 1.6 2.4e-11 44.1 0.0 4.6 3 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OAP58288.1 - 7e-27 93.2 6.1 2.1e-08 34.3 0.1 6.5 4 1 3 7 7 7 6 Ankyrin repeats (many copies) Ank PF00023.30 OAP58288.1 - 5.9e-23 80.3 15.1 1.2e-06 28.7 0.0 7.6 7 0 0 7 7 7 4 Ankyrin repeat Ank_3 PF13606.6 OAP58288.1 - 6.6e-23 78.3 5.7 2.9e-05 24.1 0.0 7.6 7 0 0 7 7 7 5 Ankyrin repeat Helo_like_N PF17111.5 OAP58288.1 - 2.2e-05 23.9 0.1 3.4e-05 23.3 0.1 1.2 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins SesA PF17107.5 OAP58288.1 - 0.027 14.7 0.1 0.052 13.7 0.1 1.4 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF1664 PF07889.12 OAP58289.1 - 0.00023 21.2 0.6 0.00032 20.7 0.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 OAP58289.1 - 0.00035 20.6 0.2 0.00066 19.7 0.2 1.4 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4618 PF15397.6 OAP58289.1 - 0.0046 16.4 0.1 0.0061 16.0 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4618) DUF1640 PF07798.11 OAP58289.1 - 0.0046 17.0 2.2 0.0082 16.2 1.9 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1640) Tektin PF03148.14 OAP58289.1 - 0.007 15.2 1.9 0.0087 14.9 1.3 1.3 1 1 0 1 1 1 1 Tektin family SKA2 PF16740.5 OAP58289.1 - 0.0071 16.1 0.4 0.19 11.5 0.2 2.2 1 1 1 2 2 2 1 Spindle and kinetochore-associated protein 2 Abi_C PF14355.6 OAP58289.1 - 0.0086 16.2 0.3 0.057 13.5 0.0 2.3 1 1 1 2 2 2 1 Abortive infection C-terminus KxDL PF10241.9 OAP58289.1 - 0.0088 16.3 0.5 0.016 15.5 0.5 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein Phage_HK97_TLTM PF06120.11 OAP58289.1 - 0.01 15.1 0.6 0.013 14.7 0.6 1.1 1 0 0 1 1 1 0 Tail length tape measure protein Spc7 PF08317.11 OAP58289.1 - 0.012 14.6 0.7 0.015 14.2 0.7 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF2730 PF10805.8 OAP58289.1 - 0.015 15.4 0.2 0.031 14.4 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) DASH_Dam1 PF08653.10 OAP58289.1 - 0.017 14.9 0.6 6.2 6.7 0.0 2.5 2 0 0 2 2 2 0 DASH complex subunit Dam1 Bacillus_HBL PF05791.11 OAP58289.1 - 0.026 14.4 0.4 0.04 13.7 0.4 1.4 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) CENP-H PF05837.12 OAP58289.1 - 0.028 14.8 0.3 0.043 14.2 0.3 1.3 1 0 0 1 1 1 0 Centromere protein H (CENP-H) WEMBL PF05701.11 OAP58289.1 - 0.035 12.8 0.5 0.044 12.5 0.5 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light Wtap PF17098.5 OAP58289.1 - 0.048 13.6 0.5 0.088 12.7 0.3 1.5 1 1 0 1 1 1 0 WTAP/Mum2p family DUF148 PF02520.17 OAP58289.1 - 0.062 13.4 0.4 0.18 12.0 0.6 1.6 2 0 0 2 2 2 0 Domain of unknown function DUF148 FlaC_arch PF05377.11 OAP58289.1 - 0.097 13.1 2.3 0.68 10.4 1.3 2.6 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Occludin_ELL PF07303.13 OAP58289.1 - 0.1 13.3 0.1 0.16 12.7 0.1 1.2 1 0 0 1 1 1 0 Occludin homology domain BLOC1_2 PF10046.9 OAP58289.1 - 0.11 12.9 1.1 0.28 11.5 1.2 1.7 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fib_alpha PF08702.10 OAP58289.1 - 0.14 12.3 0.9 0.21 11.7 0.9 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family NPV_P10 PF05531.12 OAP58289.1 - 0.24 11.9 1.5 4.8 7.7 1.4 2.7 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein ArfGap PF01412.18 OAP58290.1 - 9.7e-41 138.5 0.4 1.4e-40 138.0 0.4 1.2 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf HET PF06985.11 OAP58291.1 - 2.3e-13 50.8 5.8 6.9e-11 42.7 0.8 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) FB_lectin PF07367.11 OAP58291.1 - 3.9e-07 30.1 0.1 8.4e-07 29.0 0.1 1.5 1 0 0 1 1 1 1 Fungal fruit body lectin CorA PF01544.18 OAP58292.1 - 1.6e-07 30.9 0.1 2.6e-07 30.3 0.1 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein ABC_tran_CTD PF16326.5 OAP58292.1 - 0.064 13.5 0.7 3.4 8.0 0.1 2.5 2 0 0 2 2 2 0 ABC transporter C-terminal domain RyR PF02026.16 OAP58293.1 - 1.7e-12 47.4 1.1 7.1e-08 32.5 0.3 2.6 2 0 0 2 2 2 2 RyR domain Torsin PF06309.11 OAP58293.1 - 0.0069 16.5 0.0 0.018 15.1 0.0 1.6 1 0 0 1 1 1 1 Torsin Zds_C PF08632.10 OAP58294.1 - 1.5e-28 98.3 1.2 1.5e-28 98.3 1.2 2.1 2 0 0 2 2 2 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term TFIIA PF03153.13 OAP58294.1 - 0.025 14.6 40.8 0.23 11.4 23.4 2.6 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Sin_N PF04801.13 OAP58294.1 - 0.047 12.9 16.5 0.11 11.7 16.5 1.5 1 0 0 1 1 1 0 Sin-like protein conserved region CLN3 PF02487.17 OAP58294.1 - 4.4 6.2 4.6 7.3 5.5 4.6 1.2 1 0 0 1 1 1 0 CLN3 protein DUF4349 PF14257.6 OAP58295.1 - 0.049 13.1 0.1 0.062 12.7 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) DUF2244 PF10003.9 OAP58295.1 - 0.076 12.7 1.7 0.11 12.2 1.7 1.2 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) TFIIE_alpha PF02002.17 OAP58296.1 - 3.2e-12 46.2 0.0 6.7e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 TFIIE alpha subunit zinc-ribbons_6 PF07191.12 OAP58296.1 - 0.011 15.7 0.4 0.023 14.7 0.4 1.4 1 0 0 1 1 1 0 zinc-ribbons zf-TFIIB PF13453.6 OAP58296.1 - 0.046 13.1 1.2 0.11 11.8 1.2 1.7 1 0 0 1 1 1 0 Transcription factor zinc-finger zf_UBZ PF18439.1 OAP58296.1 - 0.074 12.7 1.1 11 5.7 0.1 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger PHD PF00628.29 OAP58296.1 - 0.26 11.2 2.0 3.2 7.7 0.7 2.5 2 0 0 2 2 2 0 PHD-finger GTP-bdg_M PF16360.5 OAP58296.1 - 1.2 9.8 4.9 1.9 9.1 0.2 3.1 3 0 0 3 3 3 0 GTP-binding GTPase Middle Region DUF4407 PF14362.6 OAP58296.1 - 1.8 7.9 3.8 0.76 9.1 0.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Zn_ribbon_SprT PF17283.2 OAP58296.1 - 6.6 6.7 7.4 3.7 7.5 0.7 2.8 2 1 1 3 3 3 0 SprT-like zinc ribbon domain Fungal_trans_2 PF11951.8 OAP58297.1 - 6.3e-06 25.3 0.1 9.6e-06 24.6 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Tht1 PF04163.12 OAP58298.1 - 9.4e-05 21.4 2.3 0.00016 20.6 1.8 1.8 1 1 0 1 1 1 1 Tht1-like nuclear fusion protein DUF948 PF06103.11 OAP58298.1 - 0.014 15.6 6.3 0.96 9.8 0.3 4.4 1 1 3 4 4 4 0 Bacterial protein of unknown function (DUF948) COG2 PF06148.11 OAP58298.1 - 0.014 15.5 9.5 0.32 11.1 3.1 3.3 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DEDD_Tnp_IS110 PF01548.17 OAP58298.1 - 0.033 14.1 4.0 5.8 6.8 0.1 3.3 3 0 0 3 3 3 0 Transposase DUF3516 PF12029.8 OAP58298.1 - 0.12 11.4 5.5 0.87 8.6 1.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3516) CENP-H PF05837.12 OAP58298.1 - 0.59 10.6 23.4 2.1 8.8 0.5 3.6 3 1 1 4 4 4 0 Centromere protein H (CENP-H) DUF1664 PF07889.12 OAP58298.1 - 0.65 10.0 7.3 2.3 8.3 0.4 3.4 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 OAP58298.1 - 4.5 7.3 13.6 1.6 8.8 2.7 3.4 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Neurensin PF14927.6 OAP58300.1 - 0.031 14.0 0.4 0.12 12.1 0.1 2.0 2 0 0 2 2 2 0 Neurensin SIR2 PF02146.17 OAP58301.1 - 2.2e-38 131.9 0.0 1.5e-37 129.2 0.0 1.9 1 1 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 OAP58301.1 - 0.0039 16.9 0.1 0.36 10.6 0.0 2.3 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain DUF3517 PF12030.8 OAP58303.1 - 9.5e-46 156.2 0.0 3.2e-45 154.5 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3517) UCH PF00443.29 OAP58303.1 - 1.1e-39 136.5 0.8 3e-39 135.1 0.1 2.1 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OAP58303.1 - 7.7e-24 84.9 0.0 1.5e-23 83.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ADD_ATRX PF17981.1 OAP58303.1 - 0.73 9.8 3.0 0.38 10.7 0.1 1.9 2 0 0 2 2 2 0 Cysteine Rich ADD domain RNase_P_pop3 PF08228.11 OAP58304.1 - 3.2e-09 37.0 0.0 1.2e-08 35.2 0.0 1.7 1 1 0 1 1 1 1 RNase P subunit Pop3 HMw1_D2 PF18254.1 OAP58304.1 - 0.029 14.7 0.0 1.1 9.7 0.0 2.4 2 1 1 3 3 3 0 HMW1 domain 2 ICMT PF04140.14 OAP58305.1 - 7e-28 96.9 1.1 1.2e-27 96.1 1.1 1.3 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 OAP58305.1 - 1.8e-12 47.6 0.8 1.8e-12 47.6 0.8 1.8 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.12 OAP58305.1 - 1.1e-05 25.0 0.9 1.5e-05 24.7 0.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ERG4_ERG24 PF01222.17 OAP58305.1 - 2.9e-05 23.0 1.0 4e-05 22.6 1.0 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Hexapep_2 PF14602.6 OAP58306.1 - 5.2e-13 48.5 5.8 3.8e-09 36.1 3.7 2.4 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.24 OAP58306.1 - 1.3e-12 46.9 7.0 1.1e-10 40.8 3.6 2.7 3 0 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Mac PF12464.8 OAP58306.1 - 2.9e-08 33.8 0.0 5.6e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 Maltose acetyltransferase GST_N_4 PF17172.4 OAP58307.1 - 4.8e-17 62.5 0.0 1.3e-16 61.1 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 OAP58307.1 - 1.8e-06 27.6 0.0 8.3e-06 25.5 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OAP58307.1 - 2.5e-05 24.2 0.0 4.4e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 OAP58307.1 - 0.088 13.2 0.0 0.5 10.8 0.0 2.0 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Epimerase PF01370.21 OAP58308.1 - 4e-13 49.4 0.0 6.9e-13 48.6 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OAP58308.1 - 1.2e-08 34.3 0.0 1.6e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 OAP58308.1 - 1.6e-08 34.1 0.0 1.2e-05 24.7 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein GDP_Man_Dehyd PF16363.5 OAP58308.1 - 5.3e-08 32.6 0.1 1.6e-07 31.0 0.1 1.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 OAP58308.1 - 1.4e-07 31.6 0.1 2.2e-07 31.0 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 OAP58308.1 - 9.8e-06 25.3 0.1 1.6e-05 24.6 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family KR PF08659.10 OAP58308.1 - 0.036 14.0 0.4 6 6.7 0.0 2.4 2 1 0 2 2 2 0 KR domain Polysacc_synt_2 PF02719.15 OAP58308.1 - 0.079 12.1 0.1 1.2 8.1 0.1 2.2 2 1 0 2 2 2 0 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 OAP58308.1 - 0.11 11.5 0.0 2.4 7.2 0.0 2.2 2 0 0 2 2 2 0 RmlD substrate binding domain adh_short PF00106.25 OAP58308.1 - 0.12 11.8 0.2 1 8.8 0.2 2.4 1 1 0 1 1 1 0 short chain dehydrogenase Atrophin-1 PF03154.15 OAP58309.1 - 8.3 4.6 16.2 10 4.2 16.2 1.0 1 0 0 1 1 1 0 Atrophin-1 family Methyltransf_2 PF00891.18 OAP58310.1 - 9.3e-19 67.6 0.0 1.4e-18 67.0 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain CheR PF01739.18 OAP58310.1 - 0.034 13.6 0.0 0.24 10.8 0.0 2.1 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain Methyltransf_25 PF13649.6 OAP58310.1 - 0.096 13.4 0.0 0.29 11.9 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Sugar_tr PF00083.24 OAP58311.1 - 4.5e-125 418.0 26.9 5.1e-125 417.9 26.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP58311.1 - 1e-23 83.9 40.7 8.2e-16 57.9 20.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 OAP58311.1 - 0.005 15.3 0.5 0.005 15.3 0.5 2.3 2 1 0 2 2 2 1 Transmembrane secretion effector TRI12 PF06609.13 OAP58311.1 - 0.28 9.5 8.9 0.053 11.9 3.3 2.0 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) HAD_2 PF13419.6 OAP58312.1 - 0.0017 18.5 0.0 0.0024 18.0 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OAP58312.1 - 0.0042 17.1 0.0 0.0087 16.1 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Acid_PPase PF12689.7 OAP58312.1 - 0.06 13.2 0.0 0.095 12.5 0.0 1.3 1 0 0 1 1 1 0 Acid Phosphatase FTA4 PF13093.6 OAP58313.1 - 2.1e-56 191.1 9.2 2.4e-56 190.8 9.2 1.0 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 GAS PF13851.6 OAP58313.1 - 5.6 6.3 10.8 2.3 7.5 6.2 2.3 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding Sec62 PF03839.16 OAP58314.1 - 2.3e-74 249.6 4.9 2.3e-74 249.6 4.9 2.0 2 0 0 2 2 2 1 Translocation protein Sec62 DUF2207 PF09972.9 OAP58314.1 - 0.28 9.9 2.5 0.38 9.5 1.6 1.8 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) TFIIA PF03153.13 OAP58314.1 - 3.8 7.4 25.4 0.14 12.2 19.0 1.7 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit TMEM154 PF15102.6 OAP58315.1 - 0.13 12.2 3.9 0.2 11.5 0.0 2.3 2 0 0 2 2 2 0 TMEM154 protein family Med3 PF11593.8 OAP58315.1 - 2 7.5 5.6 3.6 6.7 5.6 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal NmrA PF05368.13 OAP58316.1 - 1.3e-25 90.3 0.2 1.6e-25 90.1 0.2 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAP58316.1 - 1.1e-16 61.3 0.0 2e-16 60.4 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAP58316.1 - 3.4e-06 26.7 0.1 1.1e-05 25.0 0.0 1.9 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OAP58316.1 - 0.00016 20.8 0.0 0.00025 20.2 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 OAP58316.1 - 0.012 14.8 0.4 0.057 12.5 0.0 1.9 2 0 0 2 2 2 0 RmlD substrate binding domain DapB_N PF01113.20 OAP58316.1 - 0.013 15.6 0.1 0.033 14.3 0.1 1.8 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.24 OAP58316.1 - 0.032 14.7 0.3 0.11 12.9 0.1 2.0 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.25 OAP58316.1 - 0.05 13.1 0.1 0.094 12.2 0.1 1.5 1 0 0 1 1 1 0 short chain dehydrogenase Abhydrolase_3 PF07859.13 OAP58318.1 - 4.5e-22 78.9 0.0 6.9e-22 78.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 OAP58318.1 - 1.1e-16 60.7 0.0 1.6e-16 60.2 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase DUF2974 PF11187.8 OAP58318.1 - 0.058 12.9 0.0 0.099 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Pkinase PF00069.25 OAP58320.1 - 4.8e-67 226.1 0.0 6e-67 225.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP58320.1 - 1.4e-31 109.8 0.0 1.7e-31 109.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OAP58320.1 - 1.2e-05 24.5 0.1 1.6e-05 24.1 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OAP58320.1 - 7.5e-05 22.2 0.1 0.00025 20.4 0.1 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OAP58320.1 - 0.00047 20.1 0.1 0.0014 18.6 0.0 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 OAP58320.1 - 0.00055 19.3 0.0 0.058 12.7 0.0 2.2 1 1 1 2 2 2 2 Kinase-like FTA2 PF13095.6 OAP58320.1 - 0.014 15.1 0.0 0.023 14.3 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 OAP58320.1 - 0.028 14.0 0.0 0.047 13.3 0.0 1.4 1 0 0 1 1 1 0 RIO1 family G-alpha PF00503.20 OAP58321.1 - 1.6e-117 392.7 0.2 1.8e-117 392.5 0.2 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 OAP58321.1 - 4.2e-15 55.6 1.2 2.2e-10 40.3 0.3 2.5 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OAP58321.1 - 1.1e-05 24.9 0.1 0.063 12.6 0.0 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 OAP58321.1 - 0.002 18.3 0.2 0.56 10.4 0.1 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase MCM PF00493.23 OAP58321.1 - 0.068 12.3 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain TniB PF05621.11 OAP58321.1 - 0.068 12.6 0.1 0.12 11.7 0.1 1.4 1 0 0 1 1 1 0 Bacterial TniB protein AAA_29 PF13555.6 OAP58321.1 - 0.099 12.4 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 OAP58321.1 - 0.11 12.6 0.3 12 6.1 0.3 3.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase Phosphorylase PF00343.20 OAP58322.1 - 0 1069.9 0.0 0 1069.7 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase Avl9 PF09794.9 OAP58323.1 - 4.6e-133 443.6 0.0 6e-133 443.2 0.0 1.1 1 0 0 1 1 1 1 Transport protein Avl9 SPA PF08616.10 OAP58323.1 - 2.7e-07 30.5 0.1 0.00092 19.1 0.0 2.5 2 0 0 2 2 2 2 Stabilization of polarity axis DUF2347 PF09804.9 OAP58323.1 - 0.00031 20.4 4.2 0.0018 17.9 0.0 3.3 3 1 0 3 3 3 1 Uncharacterized conserved protein (DUF2347) Cullin PF00888.22 OAP58324.1 - 4.9e-193 643.1 13.1 6.2e-193 642.8 13.1 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 OAP58324.1 - 4.7e-25 87.4 4.7 6.3e-25 87.0 2.5 2.5 2 0 0 2 2 2 1 Cullin protein neddylation domain SatD PF16264.5 OAP58324.1 - 0.0056 16.3 0.4 0.025 14.2 0.0 2.1 2 0 0 2 2 2 1 SatD family (SatD) HTH_34 PF13601.6 OAP58324.1 - 0.086 13.0 0.0 1.3 9.3 0.0 2.8 2 1 0 2 2 2 0 Winged helix DNA-binding domain Cupin_1 PF00190.22 OAP58325.1 - 3e-06 26.9 0.1 4.4e-06 26.4 0.1 1.2 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 OAP58325.1 - 5.6e-06 26.0 0.3 9.8e-06 25.2 0.3 1.3 1 0 0 1 1 1 1 Cupin domain ARD PF03079.14 OAP58325.1 - 0.025 14.8 0.0 0.037 14.2 0.0 1.2 1 0 0 1 1 1 0 ARD/ARD' family Cupin_6 PF12852.7 OAP58325.1 - 0.027 14.2 0.0 0.034 13.9 0.0 1.2 1 0 0 1 1 1 0 Cupin HupF_HypC PF01455.18 OAP58325.1 - 0.071 13.3 0.0 0.41 10.8 0.0 2.0 2 0 0 2 2 2 0 HupF/HypC family Mit_KHE1 PF10173.9 OAP58327.1 - 2.2e-58 197.5 0.0 3.5e-58 196.8 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related DSPc PF00782.20 OAP58328.1 - 9.9e-12 44.8 0.0 1.6e-11 44.2 0.0 1.5 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain zf-UBR PF02207.20 OAP58330.1 - 5.8e-13 48.8 4.1 5.8e-13 48.8 4.1 3.5 4 0 0 4 4 4 2 Putative zinc finger in N-recognin (UBR box) MCM PF00493.23 OAP58331.1 - 4.7e-101 336.6 0.0 7.6e-101 335.9 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 OAP58331.1 - 1.8e-38 131.2 0.4 3.2e-38 130.4 0.4 1.4 1 0 0 1 1 1 1 MCM OB domain MCM2_N PF12619.8 OAP58331.1 - 3.2e-35 121.7 37.4 3.2e-35 121.7 37.4 2.4 2 1 0 2 2 2 1 Mini-chromosome maintenance protein 2 MCM_lid PF17855.1 OAP58331.1 - 7e-25 87.3 0.4 2.2e-24 85.7 0.4 1.9 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 OAP58331.1 - 1.3e-14 54.6 0.0 3.5e-14 53.2 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 OAP58331.1 - 2.8e-08 33.4 0.1 1.9e-06 27.4 0.0 2.4 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 OAP58331.1 - 2.4e-06 27.6 0.0 5.9e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 OAP58331.1 - 0.0018 18.0 0.2 0.012 15.3 0.2 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.11 OAP58331.1 - 0.0041 17.0 0.1 0.11 12.4 0.0 2.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OAP58331.1 - 0.096 13.1 0.0 0.66 10.3 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain Zn_ribbon_2 PF12674.7 OAP58331.1 - 0.12 13.1 0.4 0.34 11.6 0.4 1.8 1 0 0 1 1 1 0 Putative zinc ribbon domain Ribosomal_L9_N PF01281.19 OAP58331.1 - 0.12 11.9 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L9, N-terminal domain DUF1272 PF06906.11 OAP58331.1 - 0.21 11.7 0.5 0.44 10.7 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) DZR PF12773.7 OAP58331.1 - 0.23 11.5 0.8 0.51 10.4 0.8 1.5 1 0 0 1 1 1 0 Double zinc ribbon IBB PF01749.20 OAP58331.1 - 0.3 11.6 2.7 1.1 9.7 2.7 2.0 1 1 0 1 1 1 0 Importin beta binding domain SNF2_N PF00176.23 OAP58332.1 - 2.3e-64 217.3 0.1 4.7e-64 216.3 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OAP58332.1 - 5.6e-23 81.4 0.4 5.4e-22 78.2 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAP58332.1 - 1.3e-08 35.0 1.0 2.8e-08 33.9 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 OAP58332.1 - 5.9e-05 22.4 0.0 0.0061 15.8 0.0 2.9 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 OAP58332.1 - 0.00038 20.3 0.0 0.00087 19.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 OAP58332.1 - 0.0016 17.7 0.0 0.0016 17.7 0.0 1.9 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase Glyco_hydro_31 PF01055.26 OAP58333.1 - 3.1e-23 82.7 0.1 4e-23 82.3 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 DUF4968 PF16338.5 OAP58333.1 - 8.8e-07 29.2 0.0 1.3e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4968) Gal_mutarotas_2 PF13802.6 OAP58333.1 - 4.4e-05 23.7 0.3 0.00031 21.0 0.3 2.2 1 1 0 1 1 1 1 Galactose mutarotase-like DUF2092 PF09865.9 OAP58333.1 - 0.088 12.2 0.1 0.24 10.7 0.1 1.7 1 0 0 1 1 1 0 Predicted periplasmic protein (DUF2092) Glyco_hydro_31 PF01055.26 OAP58334.1 - 1.5e-34 120.0 0.7 1.6e-34 119.8 0.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Glyco_hydro_31 PF01055.26 OAP58335.1 - 1.5e-35 123.2 0.0 2.8e-35 122.4 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 31 Ank_2 PF12796.7 OAP58336.1 - 1.5e-30 105.6 19.7 9.6e-11 42.1 0.2 4.6 2 1 4 6 6 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAP58336.1 - 2.5e-28 98.0 14.7 5.6e-08 33.2 0.0 6.4 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 OAP58336.1 - 1.9e-17 62.8 18.3 0.00018 21.8 0.0 7.4 7 0 0 7 7 7 5 Ankyrin repeat Ank_3 PF13606.6 OAP58336.1 - 2.7e-16 58.0 7.2 0.00014 22.0 0.0 7.3 7 0 0 7 7 7 3 Ankyrin repeat PNP_UDP_1 PF01048.20 OAP58336.1 - 4.8e-13 48.9 0.2 1.2e-12 47.6 0.2 1.6 1 1 0 1 1 1 1 Phosphorylase superfamily Ank_5 PF13857.6 OAP58336.1 - 3.8e-10 39.8 10.5 5.8e-05 23.3 0.1 6.2 3 2 5 8 8 7 3 Ankyrin repeats (many copies) NACHT PF05729.12 OAP58336.1 - 2.1e-06 27.7 0.0 5.9e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 OAP58336.1 - 1.2e-05 25.8 0.0 0.00015 22.2 0.0 2.7 3 0 0 3 3 2 1 AAA ATPase domain AAA_19 PF13245.6 OAP58336.1 - 0.0043 17.4 0.0 0.0084 16.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 OAP58336.1 - 0.0053 17.0 0.0 0.013 15.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 OAP58336.1 - 0.02 14.1 0.0 0.037 13.2 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_30 PF13604.6 OAP58336.1 - 0.022 14.5 0.0 0.046 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Ploopntkinase3 PF18751.1 OAP58336.1 - 0.042 13.8 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 Viral_helicase1 PF01443.18 OAP58336.1 - 0.072 12.8 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.22 OAP58336.1 - 0.1 13.0 0.0 0.22 11.9 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_29 PF13555.6 OAP58336.1 - 0.14 11.9 0.0 0.39 10.5 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.6 OAP58336.1 - 0.16 12.5 0.0 0.51 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 OAP58336.1 - 0.2 12.1 0.0 0.54 10.7 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sulfate_transp PF00916.20 OAP58337.1 - 2.3e-82 276.7 16.6 3e-82 276.4 16.6 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 OAP58337.1 - 6.3e-14 51.6 0.0 1.5e-13 50.4 0.0 1.7 1 0 0 1 1 1 1 STAS domain MotB_plug PF13677.6 OAP58337.1 - 0.023 14.3 0.5 0.055 13.1 0.5 1.6 1 0 0 1 1 1 0 Membrane MotB of proton-channel complex MotA/MotB STAS_2 PF13466.6 OAP58337.1 - 0.048 14.0 0.0 0.16 12.3 0.0 1.9 1 0 0 1 1 1 0 STAS domain SpoIIIAC PF06686.11 OAP58337.1 - 0.64 10.2 5.6 12 6.2 0.1 3.4 3 0 0 3 3 3 0 Stage III sporulation protein AC/AD protein family DUF1275 PF06912.11 OAP58338.1 - 1.8e-44 152.0 8.2 2.1e-44 151.8 8.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) Tcell_CD4_C PF12104.8 OAP58338.1 - 0.2 11.6 1.4 0.41 10.6 1.4 1.4 1 0 0 1 1 1 0 T cell CD4 receptor C terminal region TLP1_add_C PF18313.1 OAP58339.1 - 1.9e-32 111.0 0.1 5.3e-32 109.6 0.1 1.8 1 0 0 1 1 1 1 Thiolase-like protein type 1 additional C-terminal domain PAN_1 PF00024.26 OAP58340.1 - 0.0082 16.1 1.4 0.013 15.4 0.0 2.0 2 0 0 2 2 2 1 PAN domain DUF4834 PF16118.5 OAP58340.1 - 0.54 11.3 3.6 14 6.7 3.6 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) Apt1 PF10351.9 OAP58340.1 - 0.58 9.0 2.8 0.74 8.6 2.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Beta-lactamase PF00144.24 OAP58341.1 - 2e-20 73.3 2.0 3.3e-20 72.6 2.0 1.3 1 0 0 1 1 1 1 Beta-lactamase Helo_like_N PF17111.5 OAP58341.1 - 0.0039 16.6 1.0 0.0054 16.1 0.1 1.7 2 0 0 2 2 2 1 Fungal N-terminal domain of STAND proteins TatD_DNase PF01026.21 OAP58343.1 - 1.6e-35 122.7 0.0 2.9e-35 121.9 0.0 1.4 1 1 0 1 1 1 1 TatD related DNase DUF2014 PF09427.10 OAP58344.1 - 1.2e-89 300.2 0.1 2.2e-89 299.3 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF2014) HLH PF00010.26 OAP58344.1 - 7.9e-19 67.4 0.6 1.8e-18 66.2 0.6 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain bZIP_1 PF00170.21 OAP58344.1 - 0.00031 20.8 1.8 0.00046 20.2 0.7 1.8 2 0 0 2 2 2 1 bZIP transcription factor ZapB PF06005.12 OAP58344.1 - 0.011 16.2 2.1 0.016 15.6 0.3 2.0 2 0 0 2 2 2 0 Cell division protein ZapB bZIP_2 PF07716.15 OAP58344.1 - 0.99 9.5 3.7 1.1 9.4 1.4 2.1 2 0 0 2 2 2 0 Basic region leucine zipper Anp1 PF03452.14 OAP58346.1 - 1.8e-104 348.9 0.0 2.2e-104 348.5 0.0 1.1 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.26 OAP58346.1 - 0.037 13.8 0.0 0.068 13.0 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 Peptidase_S10 PF00450.22 OAP58347.1 - 1.4e-88 298.1 5.9 4.2e-88 296.6 5.9 1.7 1 1 0 1 1 1 1 Serine carboxypeptidase HhH-GPD PF00730.25 OAP58349.1 - 6.9e-05 23.3 0.0 0.00014 22.3 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein GHBP PF12772.7 OAP58349.1 - 0.032 13.8 2.0 0.046 13.2 2.0 1.2 1 0 0 1 1 1 0 Growth hormone receptor binding Adaptin_binding PF10199.9 OAP58349.1 - 0.053 14.1 0.4 0.11 13.1 0.4 1.5 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 DSPc PF00782.20 OAP58350.1 - 3.9e-21 75.3 0.0 5e-21 74.9 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 OAP58350.1 - 0.00012 22.3 0.0 0.00019 21.7 0.0 1.3 1 0 0 1 1 1 1 Rit1 DUSP-like domain Y_phosphatase PF00102.27 OAP58350.1 - 0.0074 15.9 0.0 0.0096 15.5 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Nop16 PF09420.10 OAP58351.1 - 1.4e-66 224.6 14.5 1.6e-66 224.4 14.5 1.0 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 Zip PF02535.22 OAP58352.1 - 3.6e-62 210.5 11.1 1e-60 205.7 11.1 2.1 1 1 0 1 1 1 1 ZIP Zinc transporter Phage_holin_Dp1 PF16938.5 OAP58352.1 - 0.057 13.6 0.8 2 8.7 0.3 2.9 2 0 0 2 2 2 0 Putative phage holin Dp-1 DUF515 PF04415.12 OAP58352.1 - 0.53 8.6 2.3 0.85 7.9 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) SR-25 PF10500.9 OAP58352.1 - 2.9 7.5 11.3 5 6.7 11.3 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Aldedh PF00171.22 OAP58353.1 - 1.3e-116 389.9 0.0 1.6e-116 389.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF5316 PF17247.2 OAP58354.1 - 0.0091 16.0 0.5 0.0091 16.0 0.5 2.1 1 1 1 2 2 2 1 Family of unknown function (DUF5316) DUF4231 PF14015.6 OAP58354.1 - 0.095 13.2 0.1 0.13 12.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) NAD_binding_10 PF13460.6 OAP58355.1 - 3.9e-08 33.4 0.1 2.1e-07 31.0 0.1 2.0 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 OAP58355.1 - 0.00089 18.9 0.2 0.0018 17.8 0.2 1.5 2 0 0 2 2 2 1 NmrA-like family RdRP PF05183.12 OAP58356.1 - 1.9e-114 383.4 0.0 3.2e-114 382.7 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase AAA_12 PF13087.6 OAP58356.1 - 1.9e-46 158.2 0.0 3.7e-46 157.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 OAP58356.1 - 1.3e-43 149.6 0.5 4.8e-23 82.3 0.4 2.5 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.6 OAP58356.1 - 2.1e-13 50.4 0.0 3.8e-12 46.3 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 OAP58356.1 - 2.2e-11 44.3 0.5 5.6e-11 43.0 0.1 1.9 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 OAP58356.1 - 2.9e-06 27.4 0.0 6.2e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 OAP58356.1 - 4.1e-06 26.7 0.0 0.069 12.9 0.0 3.4 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.14 OAP58356.1 - 0.00019 21.3 0.0 0.0005 20.0 0.0 1.7 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.6 OAP58356.1 - 0.00026 20.8 0.0 0.00077 19.2 0.0 1.9 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain DEAD PF00270.29 OAP58356.1 - 0.00034 20.4 0.1 0.00077 19.3 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase PhoH PF02562.16 OAP58356.1 - 0.00036 20.0 0.0 0.0012 18.3 0.0 1.9 1 1 0 1 1 1 1 PhoH-like protein AAA_22 PF13401.6 OAP58356.1 - 0.0033 17.7 0.0 0.014 15.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 OAP58356.1 - 0.0074 16.7 0.0 0.024 15.0 0.0 1.9 1 0 0 1 1 1 1 RNA helicase AAA_16 PF13191.6 OAP58356.1 - 0.0078 16.6 0.0 0.035 14.5 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 OAP58356.1 - 0.0093 16.4 0.0 0.025 15.0 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 OAP58356.1 - 0.032 13.5 0.0 0.38 9.9 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) MlrC_C PF07171.12 OAP58356.1 - 0.077 13.2 0.3 1.2 9.3 0.0 2.6 3 0 0 3 3 3 0 MlrC C-terminus UvrD-helicase PF00580.21 OAP58356.1 - 0.16 11.5 0.0 0.8 9.2 0.0 1.9 1 1 1 2 2 2 0 UvrD/REP helicase N-terminal domain SRP54 PF00448.22 OAP58356.1 - 0.16 11.5 0.1 3.5 7.2 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_28 PF13521.6 OAP58357.1 - 1.4e-27 97.0 0.0 1.7e-27 96.7 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OAP58357.1 - 0.0034 17.8 0.0 0.004 17.6 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 OAP58357.1 - 0.0076 16.8 0.0 0.011 16.3 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 OAP58357.1 - 0.01 15.6 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 OAP58357.1 - 0.053 13.8 0.0 0.11 12.8 0.0 1.7 1 1 1 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 OAP58357.1 - 0.095 12.8 0.0 0.16 12.1 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA PF00004.29 OAP58357.1 - 0.16 12.4 0.0 0.25 11.8 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Cu-oxidase_2 PF07731.14 OAP58359.1 - 9e-42 142.1 11.3 4.4e-40 136.6 0.2 4.2 4 1 0 4 4 4 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 OAP58359.1 - 2.1e-41 140.7 3.0 2.1e-41 140.7 3.0 2.6 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.22 OAP58359.1 - 3.4e-35 121.5 0.2 1e-34 119.9 0.2 1.9 1 0 0 1 1 1 1 Multicopper oxidase Mt_ATP-synt_D PF05873.12 OAP58360.1 - 3.6e-17 62.7 0.4 4.3e-17 62.4 0.4 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) Dor1 PF04124.12 OAP58360.1 - 0.023 13.4 0.4 0.028 13.1 0.4 1.1 1 0 0 1 1 1 0 Dor1-like family BORCS8 PF10167.9 OAP58360.1 - 0.079 12.9 0.2 0.16 12.0 0.2 1.6 1 1 0 1 1 1 0 BLOC-1-related complex sub-unit 8 BLOC1_2 PF10046.9 OAP58360.1 - 0.085 13.2 1.6 0.68 10.3 0.7 2.4 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 NAC PF01849.18 OAP58361.1 - 1.2e-21 76.5 0.0 3.7e-21 74.8 0.0 1.9 2 0 0 2 2 2 1 NAC domain Pes-10 PF07149.11 OAP58361.1 - 0.45 9.5 6.8 0.73 8.8 6.8 1.3 1 0 0 1 1 1 0 Pes-10 Ribosomal_L14e PF01929.17 OAP58362.1 - 7.8e-31 106.4 1.4 1e-30 106.0 1.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.29 OAP58362.1 - 2.6e-05 24.0 0.2 4.5e-05 23.2 0.2 1.4 1 0 0 1 1 1 1 KOW motif Prot_ATP_ID_OB PF16450.5 OAP58362.1 - 0.0075 16.2 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain RGS PF00615.19 OAP58363.1 - 0.054 13.8 0.0 0.32 11.3 0.0 2.1 1 1 0 1 1 1 0 Regulator of G protein signaling domain Methyltransf_23 PF13489.6 OAP58364.1 - 1.6e-14 54.1 0.0 2.7e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAP58364.1 - 1.5e-13 51.2 0.0 1.1e-12 48.4 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAP58364.1 - 3.2e-13 50.2 0.1 1.4e-09 38.6 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase domain Sterol_MT_C PF08498.10 OAP58364.1 - 8.8e-13 48.4 0.0 1.6e-12 47.5 0.0 1.4 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_31 PF13847.6 OAP58364.1 - 1.3e-10 41.3 0.0 1.5e-09 37.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 OAP58364.1 - 9.3e-08 31.7 0.0 3.1e-06 26.7 0.0 2.1 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 OAP58364.1 - 2.3e-06 28.2 0.0 6.1e-06 26.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 OAP58364.1 - 0.00022 21.0 0.0 0.00033 20.5 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_15 PF09445.10 OAP58364.1 - 0.0065 16.1 0.0 0.0095 15.5 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_32 PF13679.6 OAP58364.1 - 0.1 12.6 0.0 0.29 11.1 0.0 1.8 2 1 0 2 2 2 0 Methyltransferase domain FtsJ PF01728.19 OAP58364.1 - 0.14 12.3 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase GTP_EFTU PF00009.27 OAP58365.1 - 2.6e-66 222.9 0.1 3.8e-66 222.3 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 OAP58365.1 - 3.8e-32 110.6 0.0 1.4e-31 108.8 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 OAP58365.1 - 6.8e-22 77.3 0.0 1.3e-20 73.2 0.0 2.4 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 OAP58365.1 - 6.9e-14 52.0 0.0 2.9e-13 50.0 0.0 2.2 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 OAP58365.1 - 6.3e-12 45.4 0.0 1.4e-11 44.3 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 OAP58365.1 - 0.00016 21.7 0.2 0.00049 20.1 0.1 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase Solute_trans_a PF03619.16 OAP58366.1 - 5.4e-97 324.5 11.8 6.5e-97 324.2 11.8 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha MFS_1 PF07690.16 OAP58368.1 - 1.8e-44 152.1 24.5 1.8e-44 152.1 24.5 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAP58368.1 - 2.3e-13 49.8 2.2 2.3e-13 49.8 2.2 2.5 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 OAP58368.1 - 4.7e-09 35.2 2.0 7.1e-09 34.6 2.0 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2178 PF09946.9 OAP58368.1 - 2.5 8.3 9.1 4 7.7 0.4 3.6 4 0 0 4 4 4 0 Predicted membrane protein (DUF2178) Rick_17kDa_Anti PF05433.15 OAP58369.1 - 2.2e-06 27.4 9.7 3.9e-06 26.6 9.7 1.4 1 0 0 1 1 1 1 Glycine zipper 2TM domain ATPase_gene1 PF09527.10 OAP58369.1 - 0.1 12.8 0.9 0.15 12.2 0.9 1.2 1 0 0 1 1 1 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter ABC_tran PF00005.27 OAP58370.1 - 1.7e-47 161.4 0.3 1.3e-23 84.0 0.0 4.0 2 2 0 2 2 2 2 ABC transporter 4HB PF17947.1 OAP58370.1 - 1.3e-29 102.1 1.4 3.8e-29 100.6 1.4 1.9 1 0 0 1 1 1 1 Four helical bundle domain AAA_21 PF13304.6 OAP58370.1 - 3.3e-16 60.0 0.1 0.0022 17.8 0.0 5.1 4 1 0 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OAP58370.1 - 1.3e-15 57.5 0.0 1.8e-06 27.6 0.0 3.5 2 1 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 OAP58370.1 - 1.2e-10 42.3 4.5 3.9e-05 24.2 0.1 3.8 4 0 0 4 4 3 2 AAA domain AAA_29 PF13555.6 OAP58370.1 - 3.3e-09 36.3 0.2 0.0025 17.5 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 OAP58370.1 - 2.1e-07 31.0 0.1 0.001 19.0 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OAP58370.1 - 1.3e-06 28.5 0.0 0.0061 16.6 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_28 PF13521.6 OAP58370.1 - 3.3e-06 27.4 0.0 0.037 14.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 OAP58370.1 - 7.9e-06 26.4 0.1 0.11 12.9 0.0 3.4 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 OAP58370.1 - 1.1e-05 25.7 0.2 0.23 11.7 0.0 3.8 5 0 0 5 5 3 2 AAA domain AAA_18 PF13238.6 OAP58370.1 - 2.2e-05 25.0 0.1 0.67 10.5 0.0 3.4 3 0 0 3 3 2 2 AAA domain DUF87 PF01935.17 OAP58370.1 - 2.7e-05 24.4 0.0 0.17 12.0 0.0 3.6 2 1 1 3 3 3 1 Helicase HerA, central domain AAA PF00004.29 OAP58370.1 - 3.5e-05 24.2 0.4 0.79 10.1 0.0 4.5 4 1 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.9 OAP58370.1 - 3.7e-05 23.5 0.0 0.07 12.9 0.0 2.9 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.23 OAP58370.1 - 0.00011 22.3 0.1 0.0037 17.3 0.0 2.8 2 0 0 2 2 2 1 Dynamin family AAA_15 PF13175.6 OAP58370.1 - 0.00011 22.0 0.6 0.71 9.5 0.0 3.4 3 1 1 4 4 4 2 AAA ATPase domain AAA_27 PF13514.6 OAP58370.1 - 0.00013 21.6 0.0 0.098 12.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 OAP58370.1 - 0.00017 21.5 0.0 0.11 12.4 0.0 2.5 2 0 0 2 2 2 1 NACHT domain RNA_helicase PF00910.22 OAP58370.1 - 0.0003 21.1 0.0 0.81 10.1 0.0 2.7 2 0 0 2 2 2 1 RNA helicase MeaB PF03308.16 OAP58370.1 - 0.00038 19.5 0.1 0.59 9.1 0.0 2.5 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_33 PF13671.6 OAP58370.1 - 0.00043 20.5 0.0 0.57 10.3 0.0 3.0 2 0 0 2 2 2 1 AAA domain G-alpha PF00503.20 OAP58370.1 - 0.00058 19.1 0.1 0.78 8.8 0.0 2.7 3 0 0 3 3 3 2 G-protein alpha subunit AAA_24 PF13479.6 OAP58370.1 - 0.00084 19.1 0.0 1.6 8.4 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_30 PF13604.6 OAP58370.1 - 0.002 17.8 0.0 2.7 7.7 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.6 OAP58370.1 - 0.0047 17.0 0.0 5.8 7.0 0.0 2.9 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 OAP58370.1 - 0.0077 16.5 0.0 1.5 9.1 0.0 3.0 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit ATP_bind_1 PF03029.17 OAP58370.1 - 0.008 16.0 0.0 4 7.2 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein HEAT_2 PF13646.6 OAP58370.1 - 0.011 16.1 0.2 1.9 8.9 0.1 3.5 3 1 1 4 4 2 0 HEAT repeats CLP1_P PF16575.5 OAP58370.1 - 0.012 15.4 0.0 0.63 9.8 0.0 2.6 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Roc PF08477.13 OAP58370.1 - 0.012 15.8 0.0 8.9 6.6 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NB-ARC PF00931.22 OAP58370.1 - 0.013 14.7 0.1 0.45 9.7 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain cobW PF02492.19 OAP58370.1 - 0.019 14.5 0.0 11 5.5 0.0 3.0 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain IstB_IS21 PF01695.17 OAP58370.1 - 0.024 14.4 0.0 12 5.6 0.0 2.8 2 0 0 2 2 2 0 IstB-like ATP binding protein Rad17 PF03215.15 OAP58370.1 - 0.025 14.5 0.0 1.7 8.5 0.0 2.5 2 0 0 2 2 2 0 Rad17 P-loop domain Septin PF00735.18 OAP58370.1 - 0.027 13.7 0.0 3.9 6.7 0.0 2.7 2 0 0 2 2 2 0 Septin ATPase_2 PF01637.18 OAP58370.1 - 0.028 14.3 0.1 3.8 7.4 0.0 3.0 3 0 0 3 3 2 0 ATPase domain predominantly from Archaea Cytidylate_kin PF02224.18 OAP58370.1 - 0.033 13.9 0.0 5.7 6.6 0.0 2.6 2 0 0 2 2 2 0 Cytidylate kinase AAA_5 PF07728.14 OAP58370.1 - 0.035 14.1 0.1 20 5.2 0.0 3.5 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) T2SSE PF00437.20 OAP58370.1 - 0.038 13.1 0.1 2.6 7.0 0.0 2.7 3 0 0 3 3 2 0 Type II/IV secretion system protein Ploopntkinase3 PF18751.1 OAP58370.1 - 0.064 13.2 0.0 11 5.9 0.0 2.5 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 DUF815 PF05673.13 OAP58370.1 - 0.075 12.2 0.0 11 5.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Mg_chelatase PF01078.21 OAP58370.1 - 0.077 12.4 0.0 3.7 6.9 0.0 2.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 OAP58370.1 - 0.083 12.4 0.0 14 5.1 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region MukB PF04310.12 OAP58370.1 - 0.099 12.4 0.0 13 5.5 0.0 2.5 2 0 0 2 2 2 0 MukB N-terminal ATP-synt_ab PF00006.25 OAP58370.1 - 0.13 11.9 0.0 10 5.7 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain HEAT PF02985.22 OAP58370.1 - 0.19 12.1 0.1 29 5.3 0.0 3.5 3 0 0 3 3 2 0 HEAT repeat AAA_13 PF13166.6 OAP58370.1 - 6.5 5.3 11.1 2.3 6.8 0.0 3.6 4 0 0 4 4 3 0 AAA domain FMO-like PF00743.19 OAP58371.1 - 6e-14 51.3 0.7 9.1e-12 44.2 0.2 2.7 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OAP58371.1 - 5.7e-10 39.3 0.0 5e-09 36.3 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAP58371.1 - 1.3e-05 24.9 0.0 0.13 11.8 0.0 2.9 3 0 0 3 3 3 2 FAD dependent oxidoreductase K_oxygenase PF13434.6 OAP58371.1 - 3.4e-05 23.1 0.1 0.00022 20.5 0.0 2.2 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 OAP58371.1 - 4.3e-05 23.6 0.1 0.047 13.7 0.0 3.4 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 OAP58371.1 - 7.9e-05 22.0 0.0 0.071 12.3 0.0 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAP58371.1 - 0.00082 18.7 0.0 0.035 13.4 0.0 2.4 2 0 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.6 OAP58371.1 - 0.0013 18.1 0.2 0.053 12.8 0.1 3.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAP58371.1 - 0.049 12.3 0.4 0.69 8.6 0.0 2.6 3 0 0 3 3 3 0 HI0933-like protein GIDA PF01134.22 OAP58371.1 - 0.07 12.2 1.5 8.4 5.4 0.0 2.9 3 0 0 3 3 3 0 Glucose inhibited division protein A Cu_amine_oxid PF01179.20 OAP58372.1 - 3.9e-107 358.7 0.0 9.7e-105 350.8 0.0 2.1 1 1 0 1 1 1 1 Copper amine oxidase, enzyme domain DUF1965 PF09248.10 OAP58372.1 - 7.3e-17 60.9 0.0 1.8e-16 59.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1965) Cu_amine_oxidN2 PF02727.16 OAP58372.1 - 5.6e-05 23.3 0.0 0.00011 22.4 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Clr5 PF14420.6 OAP58374.1 - 1.2e-17 63.8 1.8 4.3e-17 62.1 1.8 2.0 1 0 0 1 1 1 1 Clr5 domain TPR_12 PF13424.6 OAP58374.1 - 0.036 14.3 4.6 0.22 11.8 0.7 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 OAP58374.1 - 0.094 12.8 2.9 1.9 8.7 0.6 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 OAP58374.1 - 0.18 11.7 5.6 9.3 6.3 1.9 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 OAP58374.1 - 0.33 11.2 2.7 2 8.7 1.3 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat CDC37_N PF03234.14 OAP58375.1 - 1.8e-45 155.0 4.6 1.8e-45 155.0 4.6 3.3 4 0 0 4 4 4 1 Cdc37 N terminal kinase binding CDC37_M PF08565.11 OAP58375.1 - 2.6e-40 137.0 0.7 2.6e-40 137.0 0.7 2.1 2 0 0 2 2 2 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.10 OAP58375.1 - 5.9e-36 122.6 0.9 5.9e-36 122.6 0.9 2.4 2 0 0 2 2 2 1 Cdc37 C terminal domain Rab15_effector PF15208.6 OAP58375.1 - 0.088 12.1 0.4 7.7 5.7 0.0 2.3 2 0 0 2 2 2 0 Rab15 effector YebO PF13974.6 OAP58375.1 - 0.63 10.2 5.1 1.9 8.7 0.1 3.7 3 0 0 3 3 3 0 YebO-like protein ABC_membrane PF00664.23 OAP58376.1 - 3e-48 164.9 11.1 3.8e-48 164.5 11.1 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 OAP58376.1 - 2.3e-36 125.3 0.0 5.6e-36 124.1 0.0 1.7 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 OAP58376.1 - 2.4e-07 30.4 0.0 0.00017 21.1 0.0 3.1 2 1 1 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 OAP58376.1 - 0.0061 16.8 0.1 0.072 13.4 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OAP58376.1 - 0.0095 16.3 0.1 0.035 14.5 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 OAP58376.1 - 0.011 15.5 0.0 0.027 14.2 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain IstB_IS21 PF01695.17 OAP58376.1 - 0.025 14.3 0.0 0.22 11.3 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA PF00004.29 OAP58376.1 - 0.027 14.9 0.0 0.14 12.6 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_ATPase PF09818.9 OAP58376.1 - 0.058 12.2 0.6 0.13 11.0 0.1 1.8 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_25 PF13481.6 OAP58376.1 - 0.13 11.8 0.0 1.3 8.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.7 OAP58376.1 - 0.17 10.7 0.0 0.28 10.1 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_23 PF13476.6 OAP58376.1 - 0.18 12.3 0.0 0.18 12.3 0.0 2.2 3 0 0 3 3 3 0 AAA domain SbcCD_C PF13558.6 OAP58376.1 - 1.5 9.1 5.0 1.8 8.8 0.7 3.2 3 1 0 3 3 3 0 Putative exonuclease SbcCD, C subunit MBOAT PF03062.19 OAP58377.1 - 8.7e-16 58.2 19.7 1.3e-15 57.7 19.7 1.4 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 OAP58377.1 - 0.0018 18.5 4.0 0.0062 16.8 4.0 1.9 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family WD40 PF00400.32 OAP58378.1 - 2.5e-32 110.4 24.2 3e-07 31.0 0.0 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAP58378.1 - 1.9e-12 47.3 0.0 0.16 12.3 0.0 5.2 3 1 3 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 OAP58378.1 - 0.036 12.6 0.3 0.08 11.5 0.1 1.6 2 0 0 2 2 2 0 Cytochrome D1 heme domain Prok-E2_C PF14459.6 OAP58378.1 - 0.51 10.5 3.3 1.1 9.4 3.3 1.5 1 0 0 1 1 1 0 Prokaryotic E2 family C WD40 PF00400.32 OAP58379.1 - 6.8e-39 131.2 11.7 2.8e-06 28.0 0.1 7.5 7 1 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAP58379.1 - 2.1e-15 56.8 0.0 0.0021 18.3 0.0 5.4 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OAP58379.1 - 3e-05 24.0 0.0 0.00064 19.7 0.0 2.5 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 OAP58379.1 - 3.2e-05 22.8 0.2 0.041 12.5 0.1 2.7 1 1 1 2 2 2 2 Nucleoporin Nup120/160 WD40_like PF17005.5 OAP58379.1 - 0.0011 18.4 0.0 0.0019 17.6 0.0 1.4 1 0 0 1 1 1 1 WD40-like domain Frtz PF11768.8 OAP58379.1 - 0.25 9.6 0.0 0.36 9.1 0.0 1.1 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz Orbi_VP6 PF01516.16 OAP58379.1 - 0.51 9.8 10.7 0.99 8.9 10.7 1.4 1 0 0 1 1 1 0 Orbivirus helicase VP6 Tetraspanin PF00335.20 OAP58381.1 - 0.0028 17.4 0.2 0.0028 17.4 0.2 2.1 2 0 0 2 2 2 1 Tetraspanin family E1-E2_ATPase PF00122.20 OAP58381.1 - 0.029 13.9 0.7 0.029 13.9 0.7 1.9 2 1 0 2 2 2 0 E1-E2 ATPase Phage_holin_3_6 PF07332.11 OAP58381.1 - 4.8 7.2 20.1 7.1 6.7 12.6 2.3 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III DUF4188 PF13826.6 OAP58382.1 - 3.8e-31 107.8 0.3 6.7e-31 107.1 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4188) Dehydratase_hem PF13816.6 OAP58382.1 - 0.0005 19.6 0.6 0.00067 19.1 0.6 1.1 1 0 0 1 1 1 1 Haem-containing dehydratase DUF3291 PF11695.8 OAP58382.1 - 0.0079 15.9 0.2 0.012 15.3 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3291) ABM PF03992.16 OAP58382.1 - 0.11 12.7 0.4 0.2 11.8 0.4 1.4 1 0 0 1 1 1 0 Antibiotic biosynthesis monooxygenase MSC PF09402.10 OAP58383.1 - 4.7e-110 368.2 0.0 7.1e-110 367.6 0.0 1.3 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.7 OAP58383.1 - 2.7e-14 52.6 0.2 2.7e-14 52.6 0.2 1.9 2 0 0 2 2 2 1 HeH/LEM domain Spt5_N PF11942.8 OAP58384.1 - 3.3 8.8 10.0 36 5.4 5.4 2.8 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Enterotoxin_HS1 PF08090.11 OAP58384.1 - 7 6.7 7.0 0.65 10.0 1.8 2.1 2 0 0 2 2 2 0 Heat stable E.coli enterotoxin 1 Ribosomal_L16 PF00252.18 OAP58385.1 - 1.6e-43 147.8 0.1 2.1e-43 147.5 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e HAMP_N3 PF18575.1 OAP58385.1 - 0.027 14.0 0.0 2.5 7.7 0.0 2.5 2 0 0 2 2 2 0 HAMP N-terminal domain 3 Ribosomal_L7Ae PF01248.26 OAP58386.1 - 2e-23 81.9 0.0 2.3e-23 81.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Pox_A_type_inc PF04508.12 OAP58387.1 - 0.018 14.8 0.3 0.066 13.1 0.3 2.0 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat TSC22 PF01166.18 OAP58387.1 - 0.93 9.9 26.2 0.22 11.8 1.0 4.4 4 0 0 4 4 4 0 TSC-22/dip/bun family His_Phos_1 PF00300.22 OAP58388.1 - 1.5e-11 44.3 3.6 5.4e-08 32.8 0.2 2.6 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) HECT PF00632.25 OAP58389.1 - 4.3e-71 239.9 0.0 1.1e-70 238.6 0.0 1.7 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) AZUL PF16558.5 OAP58389.1 - 4.4e-17 62.1 2.9 1.3e-16 60.6 2.9 1.8 1 0 0 1 1 1 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A DUF2555 PF10742.9 OAP58389.1 - 0.13 12.1 0.1 0.62 9.9 0.1 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2555) Tim17 PF02466.19 OAP58390.1 - 7.9e-32 109.9 7.7 9.6e-32 109.7 7.7 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family TraQ PF09679.10 OAP58391.1 - 0.0061 16.5 0.1 0.0061 16.5 0.1 2.0 2 0 0 2 2 2 1 Type-F conjugative transfer system pilin chaperone (TraQ) Thiamine_BP PF01910.17 OAP58392.1 - 3.5e-32 110.2 0.1 4e-32 110.0 0.1 1.0 1 0 0 1 1 1 1 Thiamine-binding protein PspB PF06667.12 OAP58392.1 - 0.1 12.7 0.1 0.16 12.0 0.1 1.4 1 0 0 1 1 1 0 Phage shock protein B DUF1335 PF07056.11 OAP58392.1 - 0.15 12.2 0.0 0.58 10.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1335) DUF3425 PF11905.8 OAP58393.1 - 2.3e-09 37.3 0.2 9.5e-09 35.3 0.2 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) Fungal_trans PF04082.18 OAP58394.1 - 1.2e-08 34.3 0.4 4.3e-08 32.5 0.4 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP58394.1 - 3.5e-05 23.8 7.0 3.5e-05 23.8 7.0 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-H2C2_2 PF13465.6 OAP58394.1 - 0.015 15.7 0.0 8.5 7.0 0.0 3.0 2 1 0 2 2 2 0 Zinc-finger double domain zf-C2H2 PF00096.26 OAP58394.1 - 0.022 15.2 4.6 0.022 15.2 4.6 3.0 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 OAP58394.1 - 0.5 10.4 9.0 0.12 12.4 1.6 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger DUF2039 PF10217.9 OAP58394.1 - 2.2 8.7 10.4 7.4 7.0 10.4 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) adh_short PF00106.25 OAP58395.1 - 3.3e-36 124.6 0.0 5.6e-36 123.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP58395.1 - 8.3e-27 94.2 0.0 1.3e-26 93.6 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_2 PF03446.15 OAP58395.1 - 0.022 14.9 0.1 0.11 12.7 0.0 2.0 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase KR PF08659.10 OAP58395.1 - 0.087 12.7 0.0 2 8.3 0.1 2.3 2 0 0 2 2 2 0 KR domain PRP4 PF08799.11 OAP58395.1 - 0.12 12.0 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like TrkA_N PF02254.18 OAP58395.1 - 0.19 12.0 0.1 0.62 10.3 0.0 1.9 3 0 0 3 3 3 0 TrkA-N domain NAD_binding_8 PF13450.6 OAP58396.1 - 1.3e-12 47.7 0.1 3.9e-12 46.2 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAP58396.1 - 0.022 14.0 0.2 0.28 10.4 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OAP58396.1 - 0.088 11.9 0.4 3.1 6.8 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A HI0933_like PF03486.14 OAP58396.1 - 0.15 10.7 0.1 0.22 10.2 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein p450 PF00067.22 OAP58397.1 - 1.8e-43 149.0 0.0 2.3e-43 148.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.18 OAP58398.1 - 1.8e-08 33.7 0.0 4.8e-08 32.3 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF3425 PF11905.8 OAP58399.1 - 2.3e-13 50.2 0.7 5.4e-13 49.0 0.1 2.0 2 1 0 2 2 2 1 Domain of unknown function (DUF3425) FMO-like PF00743.19 OAP58400.1 - 4.2e-13 48.6 0.3 4.9e-12 45.1 0.2 2.5 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 OAP58400.1 - 6.4e-09 35.4 0.2 1e-05 24.9 0.0 3.5 3 1 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 OAP58400.1 - 5e-08 32.5 0.0 2.3e-05 23.8 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAP58400.1 - 5.1e-08 33.0 0.0 1.6e-07 31.4 0.0 1.9 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 OAP58400.1 - 9.4e-06 25.1 0.1 0.00022 20.6 0.1 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAP58400.1 - 0.053 13.5 0.0 0.43 10.5 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding Fungal_trans PF04082.18 OAP58401.1 - 1e-16 60.8 1.0 2.1e-16 59.8 1.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short_C2 PF13561.6 OAP58402.1 - 1e-37 130.0 4.4 1.9e-36 125.8 4.4 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP58402.1 - 3e-36 124.7 4.1 1.9e-35 122.1 4.1 1.8 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAP58402.1 - 8.4e-09 35.6 0.3 1.2e-08 35.1 0.3 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAP58402.1 - 4.5e-07 29.6 0.3 6.7e-07 29.0 0.1 1.4 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 OAP58402.1 - 2.7e-05 24.1 0.1 4e-05 23.6 0.1 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 OAP58402.1 - 0.00021 21.5 0.2 0.00033 20.9 0.2 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain GDP_Man_Dehyd PF16363.5 OAP58402.1 - 0.023 14.1 0.0 0.032 13.6 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase DUF448 PF04296.13 OAP58402.1 - 0.082 12.8 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF448) Sugar_tr PF00083.24 OAP58403.1 - 4.4e-78 263.1 28.9 5.1e-78 262.9 28.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP58403.1 - 1.3e-29 103.2 28.3 1.3e-29 103.2 28.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TMEM215 PF15746.5 OAP58403.1 - 0.04 13.4 3.3 0.59 9.5 0.6 2.5 2 0 0 2 2 2 0 TMEM215 family FMO-like PF00743.19 OAP58404.1 - 3.2e-15 55.6 0.1 1.8e-13 49.8 0.0 2.6 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OAP58404.1 - 2e-08 34.3 0.0 7.2e-08 32.6 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 OAP58404.1 - 1.2e-07 31.2 0.0 0.011 14.9 0.0 4.2 3 1 0 4 4 4 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 OAP58404.1 - 7.3e-05 22.1 0.0 0.0043 16.3 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAP58404.1 - 0.004 17.2 0.0 0.77 9.7 0.0 3.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 OAP58404.1 - 0.005 16.1 0.9 1.1 8.4 0.0 3.5 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Malic_M PF03949.15 OAP58404.1 - 0.015 14.6 0.5 0.42 9.8 0.0 2.2 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain ARL2_Bind_BART PF11527.8 OAP58404.1 - 0.039 14.1 0.1 0.11 12.6 0.1 1.7 1 0 0 1 1 1 0 The ARF-like 2 binding protein BART NAD_Gly3P_dh_N PF01210.23 OAP58404.1 - 0.14 12.2 0.2 1.9 8.4 0.0 2.2 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus p450 PF00067.22 OAP58405.1 - 2.2e-62 211.3 0.0 2.7e-62 211.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Cyclase PF04199.13 OAP58406.1 - 1.9e-14 54.1 0.0 2.5e-14 53.7 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase adh_short_C2 PF13561.6 OAP58407.1 - 9.6e-53 179.1 0.0 1.2e-52 178.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP58407.1 - 6.7e-43 146.4 0.1 8.5e-43 146.1 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAP58407.1 - 5.5e-07 29.7 1.0 3.5e-06 27.1 1.0 2.0 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 OAP58407.1 - 0.18 10.8 0.0 0.25 10.3 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short_C2 PF13561.6 OAP58409.1 - 1.2e-53 182.1 0.1 2e-53 181.4 0.1 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP58409.1 - 5.5e-50 169.5 0.3 8.2e-50 169.0 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAP58409.1 - 5.7e-15 55.7 0.1 1.1e-14 54.7 0.1 1.4 2 0 0 2 2 2 1 KR domain CABS1 PF15367.6 OAP58409.1 - 0.0089 15.2 0.0 0.012 14.8 0.0 1.1 1 0 0 1 1 1 1 Calcium-binding and spermatid-specific protein 1 THF_DHG_CYH_C PF02882.19 OAP58409.1 - 0.07 12.5 0.1 0.85 8.9 0.0 2.6 3 1 1 4 4 4 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain RmlD_sub_bind PF04321.17 OAP58409.1 - 0.16 11.1 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Epimerase PF01370.21 OAP58409.1 - 0.16 11.4 0.1 0.42 10.0 0.1 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family GST_C_3 PF14497.6 OAP58410.1 - 5.5e-08 32.9 0.0 8.9e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OAP58410.1 - 1.8e-07 31.3 0.0 3.4e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OAP58410.1 - 5.6e-07 29.5 0.0 1.2e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 OAP58410.1 - 1.9e-06 28.2 0.0 2.9e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 OAP58410.1 - 2.8e-06 27.6 0.0 5.1e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OAP58410.1 - 2.4e-05 24.5 0.0 4.2e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 OAP58410.1 - 0.0014 18.4 0.0 0.0027 17.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Syntaxin-5_N PF11416.8 OAP58410.1 - 0.11 11.7 0.9 0.25 10.6 0.9 1.5 1 0 0 1 1 1 0 Syntaxin-5 N-terminal, Sly1p-binding domain Metallophos PF00149.28 OAP58414.1 - 3e-12 47.5 0.2 5.1e-12 46.7 0.2 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Drf_FH1 PF06346.12 OAP58415.1 - 9.4 5.9 20.1 8 6.2 15.9 1.8 1 1 0 1 1 1 0 Formin Homology Region 1 HrpB1_HrpK PF09613.10 OAP58416.1 - 0.014 15.0 0.0 0.042 13.5 0.0 1.8 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB1_HrpK) Zeta_toxin PF06414.12 OAP58416.1 - 0.034 13.4 0.0 0.07 12.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_16 PF13191.6 OAP58416.1 - 0.15 12.4 0.0 0.41 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain TPR_2 PF07719.17 OAP58416.1 - 0.18 12.0 2.0 49 4.4 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 OAP58416.1 - 0.21 11.5 3.7 3.6 7.6 0.2 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat DNA_pol_B_thumb PF14791.6 OAP58417.1 - 2e-20 72.7 0.0 1.1e-19 70.4 0.1 2.2 2 0 0 2 2 2 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.9 OAP58417.1 - 1.9e-19 69.2 0.4 4.3e-19 68.1 0.4 1.7 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda DNA_pol_B_palm PF14792.6 OAP58417.1 - 3.1e-16 59.6 0.0 7.4e-16 58.4 0.0 1.7 1 1 0 1 1 1 1 DNA polymerase beta palm HHH_8 PF14716.6 OAP58417.1 - 2.5e-09 37.4 0.1 6e-09 36.2 0.1 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_5 PF14520.6 OAP58417.1 - 0.0036 17.9 0.0 0.24 12.0 0.0 2.6 2 0 0 2 2 2 1 Helix-hairpin-helix domain BRCT_2 PF16589.5 OAP58417.1 - 0.016 15.6 0.0 0.61 10.5 0.0 2.4 2 0 0 2 2 2 0 BRCT domain, a BRCA1 C-terminus domain Ribophorin_I PF04597.14 OAP58418.1 - 4.3e-150 500.7 0.1 4.9e-150 500.6 0.1 1.0 1 0 0 1 1 1 1 Ribophorin I Xan_ur_permease PF00860.20 OAP58418.1 - 0.19 10.4 0.1 0.44 9.2 0.0 1.5 2 0 0 2 2 2 0 Permease family 2Fe-2S_thioredx PF01257.19 OAP58419.1 - 5.3e-60 201.5 0.2 7.2e-60 201.1 0.2 1.2 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin F-box-like PF12937.7 OAP58420.1 - 5.7e-07 29.3 0.5 1.1e-06 28.5 0.5 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAP58420.1 - 3.7e-05 23.5 0.0 0.00011 22.0 0.0 1.8 1 0 0 1 1 1 1 F-box domain VTC PF09359.10 OAP58421.1 - 1.3e-100 336.4 0.1 1.3e-100 336.4 0.1 1.6 2 0 0 2 2 2 1 VTC domain DUF202 PF02656.15 OAP58421.1 - 3.8e-12 46.5 3.7 8.3e-12 45.4 3.7 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF202) SPX PF03105.19 OAP58421.1 - 1.2e-11 45.2 24.3 3.2e-06 27.3 0.1 4.2 3 1 1 4 4 4 3 SPX domain LXG PF04740.12 OAP58421.1 - 0.045 13.5 4.1 0.063 13.0 2.7 2.0 1 1 1 2 2 2 0 LXG domain of WXG superfamily Rad17 PF03215.15 OAP58422.1 - 4.9e-22 78.8 0.0 8.8e-22 77.9 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain Peptidase_M16 PF00675.20 OAP58422.1 - 0.00014 21.9 0.5 0.00026 21.0 0.0 1.7 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) AAA_16 PF13191.6 OAP58422.1 - 0.00014 22.3 0.0 0.00034 21.0 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 OAP58422.1 - 0.00096 19.6 0.0 0.0027 18.2 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 OAP58422.1 - 0.0015 18.3 0.1 0.0078 15.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 OAP58422.1 - 0.015 15.0 0.0 0.028 14.2 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 OAP58422.1 - 0.036 14.1 0.1 0.068 13.2 0.1 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 OAP58422.1 - 0.037 14.3 0.3 0.19 12.0 0.3 2.2 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 OAP58422.1 - 0.056 13.6 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 OAP58422.1 - 0.074 12.1 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_5 PF07728.14 OAP58422.1 - 0.11 12.5 0.2 0.41 10.7 0.2 2.0 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_6 PF12774.7 OAP58422.1 - 0.12 11.3 0.0 0.21 10.5 0.0 1.2 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region Nbs1_C PF08599.10 OAP58422.1 - 0.21 11.8 5.4 2 8.6 1.0 2.9 2 0 0 2 2 2 0 DNA damage repair protein Nbs1 DHHC PF01529.20 OAP58423.1 - 4.7e-32 110.9 5.1 4.7e-32 110.9 5.1 1.9 2 0 0 2 2 2 1 DHHC palmitoyltransferase zf-UBR PF02207.20 OAP58423.1 - 0.11 12.6 6.1 0.18 12.0 6.1 1.2 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) MARVEL PF01284.23 OAP58424.1 - 8.4e-09 35.6 19.5 2.7e-07 30.7 18.3 2.1 1 1 1 2 2 2 2 Membrane-associating domain Claudin_3 PF06653.11 OAP58424.1 - 0.035 14.1 13.1 0.043 13.8 4.5 2.2 1 1 1 2 2 2 0 Tight junction protein, Claudin-like VWA PF00092.28 OAP58425.1 - 1e-09 38.9 0.6 2.9e-09 37.4 0.1 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_2 PF13519.6 OAP58425.1 - 4.6e-05 24.0 0.0 0.00012 22.7 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain SARAF PF06682.12 OAP58425.1 - 0.16 11.6 0.0 0.16 11.6 0.0 2.2 1 1 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis Mito_carr PF00153.27 OAP58426.1 - 1.5e-59 197.9 2.5 5.4e-20 71.1 0.0 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF295 PF03478.18 OAP58426.1 - 0.014 14.9 0.6 2.4 7.8 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF295) Serine_protease PF18405.1 OAP58426.1 - 0.029 13.5 0.4 0.34 10.0 0.2 2.4 2 0 0 2 2 2 0 Gammaproteobacterial serine protease F-box-like PF12937.7 OAP58427.1 - 7.5e-06 25.7 0.2 1.5e-05 24.8 0.2 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAP58427.1 - 0.0009 19.1 0.2 0.0019 18.0 0.2 1.5 1 0 0 1 1 1 1 F-box domain TPR_2 PF07719.17 OAP58427.1 - 0.043 13.9 0.2 0.44 10.8 0.2 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat BRO1 PF03097.18 OAP58427.1 - 0.085 11.6 0.3 0.12 11.1 0.3 1.2 1 0 0 1 1 1 0 BRO1-like domain MIT PF04212.18 OAP58427.1 - 0.11 12.5 0.3 0.23 11.5 0.3 1.4 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain KAR9 PF08580.10 OAP58428.1 - 4.6e-149 498.1 4.9 4.6e-149 498.1 4.9 1.3 1 1 0 1 1 1 1 Yeast cortical protein KAR9 PLU-1 PF08429.11 OAP58428.1 - 2.2e-05 23.8 2.2 0.076 12.2 0.2 3.3 2 1 1 3 3 3 2 PLU-1-like protein Helo_like_N PF17111.5 OAP58428.1 - 0.027 13.8 2.7 0.48 9.8 0.1 2.7 2 1 0 2 2 2 0 Fungal N-terminal domain of STAND proteins SPOUT_MTase PF02590.17 OAP58428.1 - 0.074 13.0 0.3 0.36 10.8 0.0 2.3 2 0 0 2 2 2 0 Predicted SPOUT methyltransferase DUF4332 PF14229.6 OAP58428.1 - 0.3 11.3 4.5 0.4 10.9 0.6 2.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4332) RuvA_C PF07499.13 OAP58428.1 - 0.42 11.1 2.5 0.39 11.2 0.8 1.9 2 0 0 2 2 2 0 RuvA, C-terminal domain DNA_repr_REX1B PF14966.6 OAP58428.1 - 2 9.2 6.6 12 6.6 0.3 3.3 4 0 0 4 4 4 0 DNA repair REX1-B BCL_N PF04714.13 OAP58428.1 - 5.3 7.2 8.3 5.2 7.2 0.4 3.4 3 0 0 3 3 3 0 BCL7, N-terminal conserver region DUF2353 PF09789.9 OAP58428.1 - 5.4 6.3 8.4 0.75 9.1 2.0 2.2 2 1 0 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) Mod_r PF07200.13 OAP58428.1 - 5.8 7.0 12.0 0.61 10.2 0.5 3.9 4 1 0 4 4 4 0 Modifier of rudimentary (Mod(r)) protein Val_tRNA-synt_C PF10458.9 OAP58428.1 - 8 6.8 7.9 0.69 10.2 0.5 3.1 4 0 0 4 4 4 0 Valyl tRNA synthetase tRNA binding arm AOX PF01786.17 OAP58429.1 - 5.1e-95 317.1 0.1 7.1e-95 316.6 0.1 1.2 1 0 0 1 1 1 1 Alternative oxidase Acylphosphatase PF00708.18 OAP58430.1 - 7.5e-26 90.4 0.2 8.3e-26 90.2 0.2 1.0 1 0 0 1 1 1 1 Acylphosphatase Fer4_23 PF18009.1 OAP58430.1 - 0.18 12.3 0.0 0.19 12.1 0.0 1.1 1 0 0 1 1 1 0 4Fe-4S iron-sulfur cluster binding domain GFA PF04828.14 OAP58432.1 - 9.4e-24 83.6 0.0 1.2e-23 83.2 0.0 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Aldolase_II PF00596.21 OAP58433.1 - 1e-45 156.0 0.2 1.3e-45 155.7 0.2 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain TetR_N PF00440.23 OAP58433.1 - 0.11 12.4 0.4 0.48 10.3 0.0 2.2 2 0 0 2 2 2 0 Bacterial regulatory proteins, tetR family PH PF00169.29 OAP58434.1 - 8.3e-10 39.1 0.0 2.2e-09 37.8 0.0 1.8 1 0 0 1 1 1 1 PH domain Anillin PF08174.11 OAP58434.1 - 0.0001 22.7 0.2 0.00027 21.4 0.0 1.9 2 0 0 2 2 2 1 Cell division protein anillin Orthopox_F8 PF05886.11 OAP58434.1 - 0.074 13.2 0.1 0.36 11.0 0.1 2.2 1 0 0 1 1 1 0 Orthopoxvirus F8 protein DEAD PF00270.29 OAP58435.1 - 5.1e-31 107.8 0.0 9.5e-31 106.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAP58435.1 - 3.1e-16 59.7 0.2 1.7e-15 57.3 0.3 2.2 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAP58435.1 - 2.9e-05 24.1 0.0 0.00021 21.3 0.0 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 OAP58435.1 - 0.15 10.8 0.3 0.69 8.6 0.0 2.1 2 0 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 HA2 PF04408.23 OAP58436.1 - 1.3e-23 83.4 0.0 3.2e-23 82.1 0.0 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 OAP58436.1 - 7.7e-15 55.0 0.1 2.4e-14 53.4 0.0 1.9 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 OAP58436.1 - 3.6e-12 46.6 0.0 8e-12 45.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 OAP58436.1 - 0.00014 21.7 0.0 0.0003 20.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 OAP58436.1 - 0.00019 21.7 0.1 0.0012 19.1 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.6 OAP58436.1 - 0.011 15.5 0.0 0.023 14.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain T2SSE PF00437.20 OAP58436.1 - 0.068 12.2 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein ABC_tran PF00005.27 OAP58436.1 - 0.072 13.6 0.0 0.25 11.9 0.0 1.9 1 0 0 1 1 1 0 ABC transporter AAA_19 PF13245.6 OAP58436.1 - 0.075 13.4 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 OAP58436.1 - 0.082 12.8 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase PIR PF00399.19 OAP58437.1 - 8.2e-91 296.0 174.9 3.8e-07 29.5 3.7 16.3 10 6 6 16 16 16 16 Yeast PIR protein repeat MTS PF05175.14 OAP58438.1 - 0.071 12.7 0.0 17 4.9 0.0 2.7 2 1 0 3 3 3 0 Methyltransferase small domain Extensin-like_C PF06904.12 OAP58438.1 - 0.096 12.7 0.0 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 Extensin-like protein C-terminus Cullin PF00888.22 OAP58439.1 - 2.1e-20 72.9 0.0 3.9e-20 72.0 0.0 1.3 1 0 0 1 1 1 1 Cullin family ANAPC2 PF08672.11 OAP58439.1 - 1.9e-18 66.7 0.0 4.9e-18 65.4 0.0 1.8 1 0 0 1 1 1 1 Anaphase promoting complex (APC) subunit 2 Fungal_trans_2 PF11951.8 OAP58440.1 - 1.7e-07 30.4 0.0 3.1e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain TauD PF02668.16 OAP58441.1 - 2.4e-25 89.8 0.0 3.5e-25 89.3 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Glyco_transf_24 PF18404.1 OAP58443.1 - 4.5e-149 495.1 2.6 1.2e-148 493.8 2.4 1.7 2 0 0 2 2 2 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 OAP58443.1 - 1.4e-65 221.8 0.0 6.3e-64 216.4 0.0 2.4 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_15 PF18403.1 OAP58443.1 - 5.1e-52 176.9 0.0 4.9e-49 167.1 0.0 2.8 3 0 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_12 PF18400.1 OAP58443.1 - 2e-46 158.3 0.0 3.3e-46 157.6 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_13 PF18401.1 OAP58443.1 - 8.9e-46 155.2 3.5 5.4e-42 142.9 0.3 3.8 4 0 0 4 4 4 2 Thioredoxin-like domain UDP-g_GGTase PF06427.11 OAP58443.1 - 9.4e-44 148.0 0.0 1.7e-43 147.1 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.20 OAP58443.1 - 0.00078 19.1 0.1 0.0015 18.1 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 8 DUF1416 PF07210.12 OAP58443.1 - 0.17 11.8 0.0 0.39 10.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1416) TRI12 PF06609.13 OAP58444.1 - 2.9e-28 98.6 24.1 3.5e-28 98.4 24.1 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAP58444.1 - 2.6e-16 59.5 55.5 2.6e-16 59.5 55.5 3.2 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF2417 PF10329.9 OAP58444.1 - 0.016 14.6 3.1 0.038 13.4 3.1 1.6 1 0 0 1 1 1 0 Region of unknown function (DUF2417) Podoplanin PF05808.11 OAP58444.1 - 0.12 12.4 0.4 0.62 10.2 0.0 2.3 3 0 0 3 3 3 0 Podoplanin DJ-1_PfpI PF01965.24 OAP58445.1 - 3e-07 30.4 0.0 4e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family FAD_binding_4 PF01565.23 OAP58446.1 - 6.6e-17 61.6 0.0 1.1e-16 60.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Glycophorin_A PF01102.18 OAP58447.1 - 0.0087 16.3 0.0 0.023 14.9 0.0 1.7 1 0 0 1 1 1 1 Glycophorin A VSP PF03302.13 OAP58447.1 - 0.031 13.1 0.8 0.05 12.5 0.8 1.3 1 0 0 1 1 1 0 Giardia variant-specific surface protein DUF2613 PF11021.8 OAP58447.1 - 0.083 13.0 0.6 0.083 13.0 0.6 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF2613) Mucin PF01456.17 OAP58447.1 - 0.32 11.0 20.4 0.049 13.6 8.8 2.6 2 0 0 2 2 2 0 Mucin-like glycoprotein SKG6 PF08693.10 OAP58447.1 - 1.3 8.5 5.2 1.4 8.4 0.5 2.5 2 0 0 2 2 2 0 Transmembrane alpha-helix domain adh_short PF00106.25 OAP58448.1 - 1.9e-27 96.0 0.1 2.6e-27 95.6 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP58448.1 - 1.2e-26 93.7 0.0 1.7e-26 93.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP58448.1 - 3.7e-09 36.8 0.0 5e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OAP58448.1 - 2.5e-05 23.6 0.1 3.6e-05 23.1 0.1 1.3 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein F420_oxidored PF03807.17 OAP58448.1 - 0.0033 18.0 0.3 0.0072 16.9 0.3 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 OAP58448.1 - 0.0041 17.2 0.0 0.007 16.4 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 OAP58448.1 - 0.0091 15.4 0.0 0.018 14.4 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 OAP58448.1 - 0.011 16.0 0.1 0.018 15.3 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain 3HCDH_N PF02737.18 OAP58448.1 - 0.018 14.9 0.5 0.03 14.2 0.5 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 OAP58448.1 - 0.13 11.9 0.1 0.26 10.9 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Glyco_tran_WecB PF03808.13 OAP58448.1 - 0.14 12.1 0.0 2.8 7.8 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family Methyltransf_31 PF13847.6 OAP58448.1 - 0.19 11.5 0.0 0.31 10.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Corona_S2 PF01601.16 OAP58448.1 - 0.28 9.6 0.1 0.41 9.1 0.1 1.2 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein PALP PF00291.25 OAP58449.1 - 2.6e-64 217.4 0.1 5.6e-64 216.4 0.1 1.5 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.28 OAP58449.1 - 4e-11 43.2 0.0 2.8e-08 34.1 0.0 2.8 2 0 0 2 2 2 2 CBS domain RRM_1 PF00076.22 OAP58450.1 - 1.1e-12 47.6 0.0 1.5e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 OAP58450.1 - 0.00015 21.7 0.0 0.00021 21.2 0.0 1.2 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif NOA36 PF06524.12 OAP58450.1 - 3.5 6.9 12.2 4.7 6.5 12.2 1.3 1 0 0 1 1 1 0 NOA36 protein EIF4E-T PF10477.9 OAP58450.1 - 6 5.6 26.3 7.3 5.3 26.3 1.0 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E Mito_carr PF00153.27 OAP58451.1 - 7.9e-75 246.9 2.3 5.8e-24 83.9 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 OAP58451.1 - 9.9e-05 21.6 0.4 0.0097 15.1 0.0 3.0 3 1 1 4 4 4 2 Gammaproteobacterial serine protease Ribosomal_L18 PF17135.4 OAP58452.1 - 1.5e-92 308.2 3.4 1.7e-92 308.0 3.4 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 OAP58452.1 - 0.00013 22.6 2.1 0.00014 22.6 0.1 2.1 2 1 0 2 2 2 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A tRNA_anti-like PF12869.7 OAP58452.1 - 0.027 14.1 0.0 0.044 13.4 0.0 1.3 1 0 0 1 1 1 0 tRNA_anti-like DUF4211 PF13926.6 OAP58452.1 - 0.066 13.3 0.1 0.12 12.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4211) Aldedh PF00171.22 OAP58453.1 - 3.9e-11 42.1 8.4 8.6e-09 34.4 4.9 2.8 2 1 0 2 2 2 2 Aldehyde dehydrogenase family TubC_N PF18563.1 OAP58453.1 - 0.1 12.6 0.9 16 5.6 0.1 2.9 2 1 1 3 3 3 0 TubC N-terminal docking domain Presenilin PF01080.17 OAP58454.1 - 1 8.1 5.3 1 8.1 5.3 1.0 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 OAP58454.1 - 1.4 8.1 5.3 1.3 8.2 5.3 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter DUF4834 PF16118.5 OAP58454.1 - 1.7 9.6 4.3 1.9 9.5 4.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF2076 PF09849.9 OAP58454.1 - 1.9 8.5 23.6 1.9 8.4 23.6 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) V_ATPase_I PF01496.19 OAP58454.1 - 3 5.7 6.9 3.3 5.5 6.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TFB6 PF17110.5 OAP58454.1 - 3.6 7.3 7.3 4 7.2 7.3 1.3 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH DNA_pol_phi PF04931.13 OAP58454.1 - 3.9 5.5 15.1 3.5 5.6 15.1 1.0 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 OAP58454.1 - 8.7 5.6 24.9 12 5.1 24.9 1.3 1 0 0 1 1 1 0 NOA36 protein iPGM_N PF06415.13 OAP58455.1 - 1.7e-77 259.7 0.0 2.5e-77 259.2 0.0 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Metalloenzyme PF01676.18 OAP58455.1 - 1.3e-72 244.2 0.0 1.5e-72 244.0 0.0 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 OAP58455.1 - 2.9e-06 26.9 0.0 8.4e-05 22.1 0.0 2.6 2 1 0 2 2 2 1 Sulfatase Phosphodiest PF01663.22 OAP58455.1 - 4.9e-06 26.4 0.0 2.8e-05 23.9 0.0 2.1 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Alk_phosphatase PF00245.20 OAP58455.1 - 0.0041 16.1 0.1 0.017 14.1 0.1 1.8 2 0 0 2 2 2 1 Alkaline phosphatase Fungal_trans PF04082.18 OAP58456.1 - 3e-13 49.4 1.5 3.9e-13 49.0 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP58456.1 - 3.6e-06 27.0 10.7 5.8e-06 26.3 10.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SRC-1 PF08832.10 OAP58456.1 - 0.21 12.7 0.5 0.51 11.4 0.5 1.7 1 0 0 1 1 1 0 Steroid receptor coactivator bZIP_2 PF07716.15 OAP58456.1 - 0.29 11.2 1.7 0.7 10.0 1.7 1.6 1 0 0 1 1 1 0 Basic region leucine zipper Amidase PF01425.21 OAP58457.1 - 1.2e-62 212.3 0.1 3.3e-60 204.3 0.5 2.2 2 1 0 2 2 2 2 Amidase PPO1_DWL PF12142.8 OAP58459.1 - 0.0045 16.7 0.1 0.036 13.8 0.0 2.3 2 0 0 2 2 2 1 Polyphenol oxidase middle domain Abhydrolase_1 PF00561.20 OAP58460.1 - 7.2e-22 78.3 0.2 6.8e-15 55.4 0.5 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAP58460.1 - 7.6e-19 69.2 4.5 9.1e-19 68.9 4.5 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAP58460.1 - 7.6e-11 41.7 0.3 8.2e-10 38.3 0.3 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 OAP58460.1 - 0.013 14.2 0.0 0.049 12.3 0.0 1.8 2 0 0 2 2 2 0 Ndr family FSH1 PF03959.13 OAP58460.1 - 0.13 11.9 0.0 0.44 10.2 0.0 1.7 2 0 0 2 2 2 0 Serine hydrolase (FSH1) HAD_SAK_1 PF10307.9 OAP58461.1 - 8.5e-71 238.0 0.0 1.3e-70 237.3 0.0 1.3 1 0 0 1 1 1 1 HAD domain family 1 in Swiss Army Knife RNA repair proteins DUF3431 PF11913.8 OAP58462.1 - 4.5e-66 222.7 0.0 5.5e-66 222.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Evr1_Alr PF04777.13 OAP58463.1 - 1.2e-28 99.5 2.5 2.2e-28 98.7 1.0 1.8 2 0 0 2 2 2 1 Erv1 / Alr family Bd3614-deam PF14439.6 OAP58463.1 - 0.12 12.5 0.1 12 6.0 0.1 2.1 2 0 0 2 2 2 0 Bd3614-like deaminase DUF5310 PF17237.2 OAP58465.1 - 5.1e-22 77.5 0.9 5.8e-22 77.3 0.9 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5310) DUF3593 PF12159.8 OAP58465.1 - 0.074 13.1 0.0 0.076 13.1 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3593) Pyr_redox_2 PF07992.14 OAP58466.1 - 6.5e-22 78.1 0.0 1.1e-10 41.3 0.0 3.2 3 0 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAP58466.1 - 5.3e-19 68.6 0.0 3.4e-17 62.7 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAP58466.1 - 1.6e-14 53.8 0.0 1.7e-09 37.3 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.19 OAP58466.1 - 7.5e-14 51.0 0.0 1.8e-12 46.5 0.0 2.2 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Shikimate_DH PF01488.20 OAP58466.1 - 2.3e-11 43.9 0.1 2e-05 24.7 0.0 3.2 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 OAP58466.1 - 5.4e-11 42.9 0.1 0.0032 18.0 0.0 3.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 OAP58466.1 - 3.9e-08 32.9 0.0 1.4e-07 31.1 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.6 OAP58466.1 - 3e-06 27.3 1.5 0.095 12.7 0.0 3.7 3 1 1 4 4 4 2 FAD-NAD(P)-binding DAO PF01266.24 OAP58466.1 - 9.7e-06 25.4 0.4 0.087 12.4 0.0 3.6 2 2 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAP58466.1 - 1.1e-05 25.5 0.1 8.8e-05 22.7 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 OAP58466.1 - 4.4e-05 22.4 0.2 0.00026 19.8 0.0 2.2 3 0 0 3 3 3 1 HI0933-like protein 2-Hacid_dh_C PF02826.19 OAP58466.1 - 7.6e-05 22.1 0.0 0.047 13.0 0.0 2.3 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 OAP58466.1 - 8.5e-05 21.8 0.1 0.017 14.2 0.1 2.5 3 0 0 3 3 3 1 FAD binding domain GIDA PF01134.22 OAP58466.1 - 0.00015 21.0 0.6 0.12 11.4 0.0 2.8 3 1 0 3 3 3 2 Glucose inhibited division protein A NAD_binding_7 PF13241.6 OAP58466.1 - 0.00031 21.1 0.0 0.68 10.4 0.0 2.5 2 1 0 2 2 2 2 Putative NAD(P)-binding ThiF PF00899.21 OAP58466.1 - 0.00061 19.2 0.0 0.34 10.2 0.0 2.2 2 0 0 2 2 2 2 ThiF family IlvN PF07991.12 OAP58466.1 - 0.0011 18.6 0.1 0.25 10.9 0.0 2.4 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain 3HCDH_N PF02737.18 OAP58466.1 - 0.0011 18.9 0.1 0.2 11.5 0.0 2.4 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 OAP58466.1 - 0.0042 16.2 0.8 0.11 11.5 0.0 2.5 3 0 0 3 3 3 1 Lycopene cyclase protein F420_oxidored PF03807.17 OAP58466.1 - 0.0047 17.5 1.1 0.083 13.5 0.1 2.9 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent AlaDh_PNT_C PF01262.21 OAP58466.1 - 0.014 14.7 0.0 0.4 9.9 0.0 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 OAP58466.1 - 0.03 13.7 0.1 0.06 12.7 0.1 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase TrkA_N PF02254.18 OAP58466.1 - 0.036 14.3 0.3 4.9 7.5 0.0 3.0 3 0 0 3 3 3 0 TrkA-N domain Trp_halogenase PF04820.14 OAP58466.1 - 0.056 12.3 3.4 1.6 7.4 0.1 2.8 3 0 0 3 3 3 0 Tryptophan halogenase Thi4 PF01946.17 OAP58466.1 - 0.084 12.1 0.1 0.86 8.8 0.0 2.4 3 0 0 3 3 3 0 Thi4 family FAD_binding_3 PF01494.19 OAP58467.1 - 2.1e-69 234.5 0.0 2.7e-69 234.1 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 OAP58467.1 - 1.4e-06 27.7 0.1 6.7e-06 25.4 0.1 2.0 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 OAP58467.1 - 1.7e-06 27.5 0.0 0.00022 20.6 0.0 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAP58467.1 - 1.4e-05 24.9 0.1 0.0033 17.1 0.0 2.6 3 0 0 3 3 3 2 FAD dependent oxidoreductase FAD_oxidored PF12831.7 OAP58467.1 - 1.8e-05 24.3 0.2 5.6e-05 22.7 0.2 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 OAP58467.1 - 4.8e-05 22.6 0.0 7.6e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.14 OAP58467.1 - 7.3e-05 21.6 0.0 0.00012 20.9 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.6 OAP58467.1 - 0.00044 20.4 0.2 0.0017 18.6 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 OAP58467.1 - 0.00076 18.8 0.0 0.0012 18.2 0.0 1.2 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 OAP58467.1 - 0.0032 16.8 0.0 0.0063 15.8 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OAP58467.1 - 0.0097 15.0 0.2 0.062 12.3 0.1 2.2 3 0 0 3 3 3 1 Lycopene cyclase protein Glyoxalase PF00903.25 OAP58468.1 - 1.9e-12 47.5 1.1 1.2e-07 32.0 0.2 2.4 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 OAP58468.1 - 0.0027 18.0 0.0 4.5 7.6 0.0 3.4 2 2 1 3 3 3 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Fungal_trans PF04082.18 OAP58469.1 - 4.5e-24 84.9 0.5 9.6e-24 83.8 0.3 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP58469.1 - 1.8e-08 34.4 11.9 3.3e-08 33.5 11.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SUIM_assoc PF16619.5 OAP58469.1 - 0.0015 18.5 3.1 0.0015 18.5 3.1 2.1 2 0 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 NOA36 PF06524.12 OAP58469.1 - 0.21 10.9 5.6 0.33 10.2 5.6 1.2 1 0 0 1 1 1 0 NOA36 protein AP3D1 PF06375.11 OAP58470.1 - 0.51 10.6 1.5 0.98 9.6 0.4 1.9 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 ABC_membrane PF00664.23 OAP58471.1 - 2.3e-80 270.1 43.5 2.1e-42 145.7 17.6 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 OAP58471.1 - 1.4e-64 216.7 0.0 7e-33 114.0 0.0 3.1 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 OAP58471.1 - 1.4e-15 57.3 1.3 0.0002 20.9 0.0 4.8 5 0 0 5 5 5 3 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 OAP58471.1 - 4.8e-11 43.1 0.0 8.2e-05 22.9 0.0 3.5 3 1 0 3 3 3 2 AAA domain AAA_16 PF13191.6 OAP58471.1 - 3.9e-08 33.9 2.9 0.00082 19.8 0.2 3.0 2 1 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 OAP58471.1 - 5.8e-08 32.9 0.0 0.81 9.4 0.0 4.3 4 1 1 5 5 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 OAP58471.1 - 1.3e-07 31.2 0.3 0.00089 19.0 0.2 2.8 3 0 0 3 3 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 OAP58471.1 - 1.7e-07 31.3 0.0 0.019 14.9 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA PF00004.29 OAP58471.1 - 2.4e-06 28.0 1.0 1.6 9.2 0.0 4.6 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 OAP58471.1 - 7.2e-06 26.0 0.0 0.058 13.1 0.0 2.6 3 0 0 3 3 3 2 AAA ATPase domain AAA_23 PF13476.6 OAP58471.1 - 1.8e-05 25.4 3.2 0.16 12.5 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_30 PF13604.6 OAP58471.1 - 3.6e-05 23.6 0.3 0.53 10.0 0.0 3.3 3 1 0 3 3 2 2 AAA domain AAA_25 PF13481.6 OAP58471.1 - 0.0001 21.9 0.0 0.26 10.9 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_7 PF12775.7 OAP58471.1 - 0.00014 21.4 0.0 0.36 10.3 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_18 PF13238.6 OAP58471.1 - 0.00015 22.4 0.0 1.1 9.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 OAP58471.1 - 0.00017 21.8 0.0 1 9.5 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 OAP58471.1 - 0.00022 21.5 0.4 0.49 10.6 0.1 3.3 3 1 0 3 3 3 1 AAA domain Rad17 PF03215.15 OAP58471.1 - 0.00024 21.1 0.0 0.12 12.3 0.0 2.7 3 0 0 3 3 2 1 Rad17 P-loop domain AAA_5 PF07728.14 OAP58471.1 - 0.00024 21.1 0.0 1.5 8.8 0.0 3.3 4 0 0 4 4 2 2 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 OAP58471.1 - 0.00024 20.9 0.0 0.13 12.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 OAP58471.1 - 0.0027 17.9 1.8 2.4 8.4 0.2 4.0 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit IstB_IS21 PF01695.17 OAP58471.1 - 0.0068 16.2 0.4 14 5.3 0.0 3.8 4 0 0 4 4 4 0 IstB-like ATP binding protein SRP54 PF00448.22 OAP58471.1 - 0.012 15.3 0.0 4.5 6.8 0.0 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain RNA_helicase PF00910.22 OAP58471.1 - 0.013 15.9 0.0 6.6 7.2 0.0 2.7 2 0 0 2 2 2 0 RNA helicase NB-ARC PF00931.22 OAP58471.1 - 0.023 13.9 0.0 1.5 7.9 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain PTN13_u3 PF16599.5 OAP58471.1 - 0.024 14.7 0.0 0.024 14.7 0.0 2.3 3 0 0 3 3 1 0 Unstructured linker region on PTN13 protein between PDZ Zeta_toxin PF06414.12 OAP58471.1 - 0.037 13.3 0.0 7.3 5.8 0.0 2.9 3 0 0 3 3 3 0 Zeta toxin G-alpha PF00503.20 OAP58471.1 - 0.037 13.2 0.0 9.2 5.3 0.0 2.3 2 0 0 2 2 2 0 G-protein alpha subunit PRK PF00485.18 OAP58471.1 - 0.046 13.5 0.0 4.1 7.1 0.0 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family MMR_HSR1 PF01926.23 OAP58471.1 - 0.066 13.3 0.0 18 5.5 0.0 2.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 OAP58471.1 - 0.084 12.6 0.0 5.1 6.8 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_17 PF13207.6 OAP58471.1 - 0.093 13.2 0.0 32 4.9 0.0 2.9 2 0 0 2 2 2 0 AAA domain MoaE PF02391.17 OAP58471.1 - 0.32 11.3 1.6 24 5.2 0.1 2.8 2 0 0 2 2 2 0 MoaE protein PAN_1 PF00024.26 OAP58472.1 - 1.5e-05 24.9 0.1 0.18 11.8 0.0 2.3 2 0 0 2 2 2 2 PAN domain PAN_3 PF08277.12 OAP58472.1 - 5.7e-05 22.8 3.7 0.0032 17.2 0.2 2.7 2 1 0 2 2 2 2 PAN-like domain PAN_4 PF14295.6 OAP58472.1 - 3.3 7.7 7.2 9 6.3 0.6 3.4 3 0 0 3 3 3 0 PAN domain DUF2183 PF09949.9 OAP58475.1 - 7.9e-22 77.5 0.2 2.1e-21 76.1 0.1 1.8 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2183) adh_short PF00106.25 OAP58476.1 - 6.9e-43 146.4 0.4 1.1e-42 145.8 0.4 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP58476.1 - 2.1e-38 132.2 0.2 3.8e-37 128.1 0.2 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP58476.1 - 1e-08 35.3 0.3 1e-08 35.3 0.3 2.0 2 1 1 3 3 3 1 KR domain Epimerase PF01370.21 OAP58476.1 - 0.051 13.0 0.1 0.078 12.4 0.1 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family ApbA PF02558.16 OAP58476.1 - 0.072 12.7 0.1 0.12 12.0 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.27 OAP58476.1 - 0.081 13.5 0.5 0.26 11.9 0.2 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 OAP58476.1 - 0.13 12.1 0.2 0.26 11.1 0.2 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 OAP58476.1 - 0.14 12.3 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase RMI1_N PF08585.12 OAP58477.1 - 3.6e-64 216.5 0.0 4.4e-64 216.2 0.0 1.1 1 0 0 1 1 1 1 RecQ mediated genome instability protein TPR_1 PF00515.28 OAP58478.1 - 6.2e-31 104.9 18.0 0.00027 20.6 0.0 13.1 16 0 0 16 16 14 6 Tetratricopeptide repeat TPR_2 PF07719.17 OAP58478.1 - 1.9e-30 102.5 39.5 0.0005 20.0 0.1 17.3 19 0 0 19 19 18 7 Tetratricopeptide repeat TPR_17 PF13431.6 OAP58478.1 - 6.7e-29 98.2 12.4 0.0051 17.1 0.0 15.1 15 1 1 16 16 16 5 Tetratricopeptide repeat TPR_16 PF13432.6 OAP58478.1 - 1e-28 99.7 32.4 5.6e-06 26.9 0.5 12.5 9 3 1 11 11 11 7 Tetratricopeptide repeat TPR_8 PF13181.6 OAP58478.1 - 1.4e-26 90.5 19.8 0.021 15.0 0.0 14.4 16 0 0 16 16 14 7 Tetratricopeptide repeat TPR_14 PF13428.6 OAP58478.1 - 2.6e-26 90.0 48.6 0.001 19.7 0.0 18.3 13 4 6 19 19 18 6 Tetratricopeptide repeat TPR_19 PF14559.6 OAP58478.1 - 6.5e-24 84.2 39.8 2.1e-07 31.3 0.6 12.1 11 3 2 14 14 11 7 Tetratricopeptide repeat TPR_11 PF13414.6 OAP58478.1 - 5.5e-23 80.4 10.3 0.00025 20.7 0.0 10.9 11 0 0 11 11 11 6 TPR repeat TPR_7 PF13176.6 OAP58478.1 - 1e-16 59.6 12.3 0.011 15.7 0.1 10.2 9 2 1 10 10 10 4 Tetratricopeptide repeat TPR_12 PF13424.6 OAP58478.1 - 1.9e-14 53.7 39.7 0.00053 20.2 0.4 12.9 14 0 0 14 14 14 4 Tetratricopeptide repeat TPR_6 PF13174.6 OAP58478.1 - 9.2e-07 29.1 31.5 0.35 11.6 0.0 14.1 18 0 0 18 18 14 2 Tetratricopeptide repeat TPR_9 PF13371.6 OAP58478.1 - 2.7e-06 27.4 21.2 0.034 14.3 0.3 8.0 9 0 0 9 9 9 2 Tetratricopeptide repeat ANAPC5 PF12862.7 OAP58478.1 - 0.0057 16.7 4.9 0.041 13.9 0.2 4.3 4 0 0 4 4 3 1 Anaphase-promoting complex subunit 5 TPR_10 PF13374.6 OAP58478.1 - 0.0086 15.9 14.8 3.7 7.5 0.3 7.5 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_22 PF18833.1 OAP58478.1 - 0.016 15.3 0.1 0.073 13.2 0.1 2.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_3 PF07720.12 OAP58478.1 - 0.026 14.5 0.1 15 5.7 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_20 PF14561.6 OAP58478.1 - 0.073 13.4 32.7 0.13 12.6 0.2 8.4 8 2 2 10 10 9 0 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 OAP58478.1 - 0.46 10.1 5.6 4 7.1 0.6 4.2 3 1 1 4 4 4 0 Bacterial type III secretion protein (HrpB1_HrpK) ANAPC3 PF12895.7 OAP58478.1 - 2.7 8.3 27.0 9.5 6.5 0.0 8.5 9 1 0 9 9 9 0 Anaphase-promoting complex, cyclosome, subunit 3 Methyltransf_25 PF13649.6 OAP58479.1 - 2.6e-14 53.7 0.0 9.5e-14 51.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAP58479.1 - 6.8e-13 49.1 0.0 4.2e-12 46.5 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAP58479.1 - 1e-10 41.4 0.0 2.7e-10 40.0 0.0 1.8 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 OAP58479.1 - 4.4e-09 36.4 0.0 5.9e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAP58479.1 - 1.4e-08 34.7 0.0 1e-07 31.9 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAP58479.1 - 2.3e-07 31.5 0.0 4.4e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OAP58479.1 - 0.014 15.0 0.0 0.029 13.9 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase small domain RE_XamI PF09572.10 OAP58479.1 - 0.075 12.7 0.0 1.3 8.6 0.0 2.0 2 0 0 2 2 2 0 XamI restriction endonuclease Epimerase PF01370.21 OAP58480.1 - 9.1e-16 58.0 0.0 2e-15 56.9 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 OAP58480.1 - 7.1e-15 55.4 0.0 1.2e-14 54.6 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 OAP58480.1 - 6.8e-13 48.7 0.0 1e-12 48.2 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 OAP58480.1 - 1.8e-12 46.9 0.0 3.8e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 OAP58480.1 - 2.5e-08 33.4 0.0 5.3e-07 29.0 0.0 2.6 1 1 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 OAP58480.1 - 7.6e-08 32.1 0.0 1.2e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 OAP58480.1 - 1.3e-06 27.8 0.0 0.46 9.6 0.0 3.3 1 1 2 3 3 3 3 Male sterility protein adh_short PF00106.25 OAP58480.1 - 0.00023 20.7 0.0 0.00048 19.7 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP58480.1 - 0.0004 20.0 0.0 0.00069 19.2 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.15 OAP58480.1 - 0.0098 15.0 0.0 0.015 14.5 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_2 PF03446.15 OAP58480.1 - 0.13 12.4 0.0 0.37 10.9 0.0 1.7 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 OAP58480.1 - 0.15 11.9 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain KR PF08659.10 OAP58480.1 - 0.17 11.8 0.0 5.7 6.8 0.0 2.3 2 0 0 2 2 2 0 KR domain Zn_clus PF00172.18 OAP58481.1 - 0.00021 21.3 4.0 0.00021 21.3 4.0 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 OAP58482.1 - 4.4e-24 85.1 38.5 4.4e-24 85.1 38.5 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2306 PF10067.9 OAP58483.1 - 4.1e-17 62.7 9.3 4.1e-17 62.7 9.3 2.0 3 0 0 3 3 3 1 Predicted membrane protein (DUF2306) DUF420 PF04238.12 OAP58483.1 - 0.012 15.9 6.6 0.03 14.6 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF420) DUF2304 PF10066.9 OAP58483.1 - 1.1 9.5 5.4 2.8 8.2 0.3 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) Zn_clus PF00172.18 OAP58484.1 - 1.3e-08 34.8 8.5 2.2e-08 34.1 8.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 OAP58484.1 - 0.0068 15.3 0.1 0.013 14.4 0.0 1.4 2 0 0 2 2 2 1 Fungal specific transcription factor domain Sporozoite_P67 PF05642.11 OAP58485.1 - 1.6 6.7 4.8 1.6 6.7 4.8 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen zf-C3Hc3H PF13891.6 OAP58486.1 - 0.093 13.1 0.1 0.093 13.1 0.1 2.1 3 0 0 3 3 3 0 Potential DNA-binding domain p450 PF00067.22 OAP58487.1 - 8.7e-63 212.7 0.0 1.1e-62 212.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Adaptin_N PF01602.20 OAP58489.1 - 4.2e-138 461.2 2.8 5.4e-138 460.8 2.8 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 OAP58489.1 - 1.3e-63 213.9 1.1 1.3e-61 207.4 0.5 2.7 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 OAP58489.1 - 1.4e-17 63.9 1.1 1.2e-07 32.0 0.0 6.0 4 2 3 7 7 7 5 HEAT repeats HEAT PF02985.22 OAP58489.1 - 1.2e-10 40.7 7.3 0.023 14.9 0.0 6.7 8 0 0 8 8 8 3 HEAT repeat HEAT_EZ PF13513.6 OAP58489.1 - 0.027 15.0 7.7 1 9.9 0.0 5.5 5 1 1 6 6 6 0 HEAT-like repeat RTP1_C1 PF10363.9 OAP58489.1 - 0.027 14.6 0.4 1.2 9.3 0.0 3.7 2 2 2 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 CLASP_N PF12348.8 OAP58489.1 - 0.07 12.7 0.1 2.8 7.4 0.0 3.0 2 1 1 3 3 3 0 CLASP N terminal CAAP1 PF15335.6 OAP58489.1 - 0.14 12.7 1.2 0.5 11.0 0.1 2.5 3 0 0 3 3 3 0 Caspase activity and apoptosis inhibitor 1 zf-CCCH_4 PF18044.1 OAP58490.1 - 1.3e-07 31.2 2.1 2.7e-07 30.2 2.1 1.6 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 OAP58490.1 - 5e-06 26.4 5.9 9.4e-06 25.5 5.9 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 OAP58490.1 - 0.00025 20.9 0.9 0.0004 20.2 0.9 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 OAP58490.1 - 0.83 10.2 4.9 1.8 9.1 4.9 1.6 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Ribosomal_S10 PF00338.22 OAP58491.1 - 5e-27 94.0 0.4 5.9e-27 93.8 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e CUE PF02845.16 OAP58492.1 - 6.3e-06 25.8 0.1 1.4e-05 24.6 0.1 1.5 1 0 0 1 1 1 1 CUE domain DUF1221 PF06760.11 OAP58492.1 - 0.17 11.3 1.3 0.32 10.5 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1221) Xpo1 PF08389.12 OAP58493.1 - 6.1e-06 26.4 0.5 6.1e-06 26.4 0.5 4.3 4 1 0 4 4 4 1 Exportin 1-like protein IBN_N PF03810.19 OAP58493.1 - 0.013 15.4 0.1 0.093 12.7 0.2 2.6 2 0 0 2 2 2 0 Importin-beta N-terminal domain E2F_TDP PF02319.20 OAP58493.1 - 0.031 14.3 0.1 0.62 10.1 0.0 2.7 2 0 0 2 2 2 0 E2F/DP family winged-helix DNA-binding domain GRIM-19 PF06212.12 OAP58494.1 - 3.6e-21 75.5 0.1 6.2e-21 74.7 0.1 1.4 1 1 0 1 1 1 1 GRIM-19 protein tRNA_m1G_MT PF01746.21 OAP58495.1 - 2.5e-24 86.1 0.0 3.3e-19 69.3 0.0 2.3 2 0 0 2 2 2 2 tRNA (Guanine-1)-methyltransferase GREB1 PF15782.5 OAP58495.1 - 0.18 8.9 1.8 0.23 8.5 1.8 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Glyco_hydro_5_C PF18564.1 OAP58496.1 - 7.3e-23 80.9 0.0 1.6e-22 79.8 0.0 1.6 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Cellulase PF00150.18 OAP58496.1 - 9.8e-16 58.0 0.8 5.2e-11 42.5 0.2 2.6 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_42 PF02449.15 OAP58496.1 - 0.00085 18.8 0.3 0.14 11.4 0.1 2.2 2 0 0 2 2 2 2 Beta-galactosidase Glyco_hydro_35 PF01301.19 OAP58496.1 - 0.011 15.3 0.1 0.02 14.6 0.1 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 35 Pkinase PF00069.25 OAP58497.1 - 7.2e-68 228.8 0.0 8.9e-68 228.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP58497.1 - 3.6e-32 111.7 0.0 4.7e-32 111.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OAP58497.1 - 0.00034 20.0 0.2 0.00061 19.2 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OAP58497.1 - 0.0039 16.2 0.4 0.0091 15.0 0.4 1.5 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 OAP58497.1 - 0.01 15.2 0.0 0.018 14.3 0.0 1.4 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 OAP58497.1 - 0.035 14.0 0.1 0.058 13.3 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family S_100 PF01023.19 OAP58497.1 - 0.04 13.6 0.1 0.12 12.1 0.1 1.8 1 0 0 1 1 1 0 S-100/ICaBP type calcium binding domain Seadorna_VP7 PF07387.11 OAP58497.1 - 0.061 12.4 0.1 0.09 11.8 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Sec23_trunk PF04811.15 OAP58498.1 - 1.2e-72 244.4 0.0 2.3e-72 243.5 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 OAP58498.1 - 2.5e-23 81.8 0.1 8e-23 80.2 0.0 1.9 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 OAP58498.1 - 5.3e-18 65.6 0.1 1.1e-17 64.5 0.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 OAP58498.1 - 1.5e-16 60.1 4.7 2.6e-16 59.4 4.7 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 OAP58498.1 - 5.7e-09 35.8 0.0 1.5e-08 34.4 0.0 1.8 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 OAP58498.1 - 0.037 13.4 0.1 0.079 12.4 0.1 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain HET PF06985.11 OAP58500.1 - 0.00048 20.5 0.0 0.001 19.5 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF5559 PF17714.1 OAP58500.1 - 0.097 12.5 0.1 0.22 11.4 0.0 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF5559) DUF1772 PF08592.11 OAP58501.1 - 8.2e-27 94.2 1.1 1.2e-26 93.6 1.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) Ribosomal_S19e PF01090.19 OAP58502.1 - 5.3e-56 188.1 0.2 6.2e-56 187.9 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Ring_hydroxyl_A PF00848.19 OAP58504.1 - 4e-16 59.6 0.3 6.5e-13 49.1 0.3 2.4 1 1 0 1 1 1 1 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.26 OAP58504.1 - 5.2e-15 55.2 0.0 1.1e-14 54.2 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain DUF3405 PF11885.8 OAP58505.1 - 3.2e-169 563.9 6.6 3.9e-169 563.6 6.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) DEC-1_N PF04625.13 OAP58505.1 - 0.82 8.6 5.3 1.3 8.0 5.3 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region eIF2A PF08662.11 OAP58508.1 - 2.1e-82 275.7 0.0 2.7e-80 268.9 0.0 2.4 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 OAP58508.1 - 0.014 16.3 3.3 4.4 8.3 0.1 5.1 5 1 0 6 6 6 0 WD domain, G-beta repeat ANAPC1 PF12859.7 OAP58510.1 - 9.4e-18 65.0 0.1 3.8e-17 63.0 0.1 2.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.22 OAP58510.1 - 1.8e-05 24.9 0.7 0.0034 17.7 0.0 3.4 3 0 0 3 3 3 1 Proteasome/cyclosome repeat Aldose_epim PF01263.20 OAP58511.1 - 6.5e-67 226.0 0.1 8e-67 225.7 0.1 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Zn_clus PF00172.18 OAP58512.1 - 8.9e-09 35.3 13.4 1.5e-08 34.6 13.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TLD PF07534.16 OAP58513.1 - 3.2e-25 89.0 0.0 9e-15 55.1 0.0 2.2 2 0 0 2 2 2 2 TLD VID27 PF08553.10 OAP58514.1 - 1.1e-186 620.1 0.0 1.4e-186 619.7 0.0 1.2 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain VID27_N PF17748.1 OAP58514.1 - 1.1e-75 253.2 0.8 1.1e-75 253.2 0.8 3.0 2 1 1 3 3 3 1 VID27 N-terminal region VID27_PH PF17747.1 OAP58514.1 - 5.5e-45 152.1 0.8 4.5e-44 149.2 0.2 2.4 2 0 0 2 2 2 1 VID27 PH-like domain Vps51 PF08700.11 OAP58515.1 - 7e-25 86.9 0.4 2.1e-24 85.4 0.4 1.9 1 0 0 1 1 1 1 Vps51/Vps67 Sec5 PF15469.6 OAP58515.1 - 0.00013 21.9 0.0 0.00032 20.6 0.0 1.7 1 1 0 1 1 1 1 Exocyst complex component Sec5 COG5 PF10392.9 OAP58515.1 - 0.0023 18.1 0.2 0.0053 16.9 0.2 1.6 1 0 0 1 1 1 1 Golgi transport complex subunit 5 FSA_C PF10479.9 OAP58515.1 - 1.5 6.9 7.6 2 6.4 7.6 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Fungal_trans_2 PF11951.8 OAP58516.1 - 4.8e-10 38.8 0.7 7.7e-10 38.1 0.7 1.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain PCI PF01399.27 OAP58517.1 - 3.1e-09 37.3 0.0 9.8e-09 35.7 0.0 1.9 1 0 0 1 1 1 1 PCI domain Rpn9_C PF18261.1 OAP58517.1 - 6.4e-07 28.9 0.6 1.7e-06 27.5 0.6 1.7 1 0 0 1 1 1 1 Rpn9 C-terminal helix TPR_19 PF14559.6 OAP58517.1 - 0.027 15.0 0.1 0.083 13.4 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat Dimerisation2 PF16864.5 OAP58517.1 - 0.03 14.3 0.1 4.1 7.4 0.0 2.5 2 0 0 2 2 2 0 Dimerisation domain TPR_8 PF13181.6 OAP58517.1 - 0.064 13.5 0.1 0.22 11.8 0.1 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 OAP58517.1 - 0.072 14.0 0.0 0.42 11.6 0.0 2.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.17 OAP58517.1 - 0.099 12.8 0.1 0.38 11.0 0.1 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat Ribosomal_S17 PF00366.20 OAP58518.1 - 2.1e-12 46.9 0.1 3.9e-12 46.1 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S17 Glyco_transf_20 PF00982.21 OAP58519.1 - 4.2e-201 668.7 0.0 4.9e-201 668.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glyco_transf_5 PF08323.11 OAP58519.1 - 0.049 13.3 0.1 0.15 11.7 0.1 1.9 2 0 0 2 2 2 0 Starch synthase catalytic domain Zn_clus PF00172.18 OAP58520.1 - 0.0033 17.5 7.7 0.0073 16.4 7.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Spt20 PF12090.8 OAP58520.1 - 6 6.4 15.3 12 5.5 15.3 1.4 1 0 0 1 1 1 0 Spt20 family Prenyltrans PF00432.21 OAP58521.1 - 9.2e-37 124.5 35.4 2.7e-10 39.8 3.1 6.4 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat dsrm PF00035.26 OAP58521.1 - 0.012 16.3 0.0 0.028 15.1 0.0 1.6 1 0 0 1 1 1 0 Double-stranded RNA binding motif SQHop_cyclase_C PF13243.6 OAP58521.1 - 0.03 13.4 0.3 0.06 12.4 0.3 1.4 1 0 0 1 1 1 0 Squalene-hopene cyclase C-terminal domain DND1_DSRM PF14709.7 OAP58521.1 - 0.14 12.4 0.1 0.32 11.3 0.1 1.5 1 0 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 MCU PF04678.13 OAP58522.1 - 5.6e-27 95.0 0.0 1.2e-26 93.9 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial calcium uniporter HEM4 PF02602.15 OAP58524.1 - 2.7e-31 108.7 0.0 1.8e-17 63.5 0.1 4.1 3 1 0 3 3 3 3 Uroporphyrinogen-III synthase HemD BLACT_WH PF17778.1 OAP58525.1 - 3e-15 55.9 0.1 6.4e-15 54.9 0.1 1.6 1 0 0 1 1 1 1 Beta-lactamase associated winged helix domain Lactamase_B PF00753.27 OAP58525.1 - 6.2e-12 45.9 2.8 1.1e-11 45.1 2.7 1.7 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OAP58525.1 - 1e-08 35.0 0.2 1.5e-08 34.4 0.2 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Aconitase PF00330.20 OAP58526.1 - 3.9e-151 504.2 0.0 4.8e-151 503.9 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 OAP58526.1 - 2.4e-45 154.1 0.0 3.9e-45 153.4 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain zf-C2H2_jaz PF12171.8 OAP58527.1 - 1.6e-08 34.6 3.1 3.2e-08 33.6 3.1 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 OAP58527.1 - 0.0053 17.1 2.0 0.0053 17.1 2.0 2.1 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OAP58527.1 - 0.028 14.8 2.6 0.049 14.1 0.1 2.2 2 0 0 2 2 2 0 Zinc-finger double domain zf-met PF12874.7 OAP58527.1 - 0.041 14.3 1.9 0.041 14.3 1.9 1.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 OAP58527.1 - 0.047 14.5 0.9 0.047 14.5 0.9 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 OAP58527.1 - 0.1 12.9 2.2 0.22 11.8 2.2 1.5 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-MYST PF17772.1 OAP58527.1 - 0.11 12.2 0.2 0.19 11.3 0.2 1.4 1 0 0 1 1 1 0 MYST family zinc finger domain Mito_carr PF00153.27 OAP58528.1 - 3.9e-42 142.1 7.9 1.5e-20 72.9 0.2 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein SNF2_N PF00176.23 OAP58529.1 - 3.4e-58 197.0 0.0 5.1e-58 196.5 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.10 OAP58529.1 - 6.6e-49 166.5 0.9 2.5e-48 164.6 0.9 2.0 2 0 0 2 2 2 1 Rad54 N terminal Helicase_C PF00271.31 OAP58529.1 - 3.3e-16 59.6 0.0 7.6e-16 58.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAP58529.1 - 8.9e-07 29.1 0.0 1.7e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 OAP58529.1 - 0.00031 20.0 0.0 0.0014 17.9 0.0 2.0 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 SWI2_SNF2 PF18766.1 OAP58529.1 - 0.15 11.7 0.0 0.44 10.2 0.0 1.8 1 1 0 1 1 1 0 SWI2/SNF2 ATPase Vac14_Fig4_bd PF11916.8 OAP58530.1 - 3e-80 268.1 5.1 3e-80 268.1 5.1 1.7 2 0 0 2 2 2 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 OAP58530.1 - 7.8e-33 112.9 0.2 1.3e-28 99.4 0.3 4.9 4 1 0 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT PF02985.22 OAP58530.1 - 1.8e-07 30.8 0.9 0.00073 19.6 0.0 4.6 3 0 0 3 3 3 1 HEAT repeat Cnd1 PF12717.7 OAP58530.1 - 7.4e-05 22.8 1.3 0.029 14.4 0.3 3.4 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 OAP58530.1 - 8.1e-05 23.0 3.2 0.0011 19.4 0.1 4.2 4 0 0 4 4 4 1 HEAT-like repeat Arm PF00514.23 OAP58530.1 - 0.0049 16.9 0.0 0.73 10.0 0.0 3.6 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat Pneumo_ncap PF03246.13 OAP58530.1 - 0.087 11.6 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Pneumovirus nucleocapsid protein HEAT_2 PF13646.6 OAP58530.1 - 0.32 11.4 10.5 1.4 9.3 0.2 4.9 7 1 1 8 8 8 0 HEAT repeats ABC_membrane PF00664.23 OAP58532.1 - 2.3e-38 132.4 14.1 3e-38 132.1 14.1 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 OAP58532.1 - 3.3e-34 118.3 0.0 7.5e-34 117.2 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 OAP58532.1 - 2.5e-06 27.1 0.0 0.0027 17.2 0.0 2.6 2 1 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 OAP58532.1 - 0.00017 22.0 0.0 0.00049 20.5 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OAP58532.1 - 0.00041 20.6 0.2 0.0049 17.1 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_21 PF13304.6 OAP58532.1 - 0.00085 19.2 0.1 0.0094 15.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_14 PF13173.6 OAP58532.1 - 0.001 19.1 0.0 0.021 14.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 OAP58532.1 - 0.005 16.6 0.0 0.012 15.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.6 OAP58532.1 - 0.0095 15.7 0.1 0.028 14.1 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 OAP58532.1 - 0.015 15.0 0.1 0.041 13.6 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.6 OAP58532.1 - 0.017 15.7 0.0 0.065 13.8 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 OAP58532.1 - 0.023 15.2 0.0 0.078 13.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 OAP58532.1 - 0.028 14.4 0.0 0.056 13.4 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain RsgA_GTPase PF03193.16 OAP58532.1 - 0.028 14.3 0.0 0.079 12.9 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase AAA PF00004.29 OAP58532.1 - 0.029 14.8 0.0 0.15 12.5 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 OAP58532.1 - 0.043 14.0 0.0 0.19 12.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 OAP58532.1 - 0.047 13.8 0.0 0.12 12.5 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_7 PF12775.7 OAP58532.1 - 0.047 13.2 0.0 0.13 11.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 OAP58532.1 - 0.051 13.7 0.2 0.91 9.7 0.0 2.7 3 0 0 3 3 2 0 AAA domain SbcCD_C PF13558.6 OAP58532.1 - 0.083 13.1 0.8 4.5 7.6 0.1 3.2 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit ATP-synt_ab PF00006.25 OAP58532.1 - 0.11 12.2 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain IstB_IS21 PF01695.17 OAP58532.1 - 0.11 12.2 1.8 15 5.3 0.0 3.1 2 1 1 3 3 3 0 IstB-like ATP binding protein AAA_25 PF13481.6 OAP58532.1 - 0.12 12.0 0.0 0.29 10.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain DAO PF01266.24 OAP58533.1 - 2.2e-25 90.0 0.5 2.5e-25 89.8 0.5 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 OAP58533.1 - 5e-05 23.3 0.3 0.11 12.4 0.1 2.2 2 0 0 2 2 2 2 FAD-NAD(P)-binding GIDA PF01134.22 OAP58533.1 - 0.00012 21.3 0.0 0.00056 19.1 0.0 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A TrkA_N PF02254.18 OAP58533.1 - 0.0022 18.2 0.0 0.016 15.4 0.0 2.1 2 0 0 2 2 2 1 TrkA-N domain GDI PF00996.18 OAP58533.1 - 0.045 12.3 0.0 0.074 11.6 0.0 1.3 1 0 0 1 1 1 0 GDP dissociation inhibitor NAD_binding_8 PF13450.6 OAP58533.1 - 0.067 13.4 0.0 0.17 12.2 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Sacchrp_dh_NADP PF03435.18 OAP58533.1 - 0.084 13.1 0.1 0.34 11.2 0.0 2.0 2 1 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain MFS_1 PF07690.16 OAP58534.1 - 3.3e-32 111.8 34.5 2.6e-24 85.8 25.8 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAP58534.1 - 2.6e-10 39.7 3.3 2.6e-10 39.7 3.3 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 OAP58534.1 - 0.0029 16.1 0.3 0.0049 15.3 0.3 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 OAP58534.1 - 0.02 13.3 6.9 0.21 9.9 2.6 2.3 2 0 0 2 2 2 0 Transmembrane secretion effector AIM24 PF01987.17 OAP58536.1 - 6.8e-48 163.1 0.0 8.6e-48 162.8 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 BTB PF00651.31 OAP58537.1 - 5.5e-12 45.9 0.0 9.5e-12 45.1 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain DUF3425 PF11905.8 OAP58539.1 - 2e-10 40.7 0.5 4.7e-10 39.5 0.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) ERM PF00769.19 OAP58539.1 - 0.037 13.8 5.8 0.056 13.3 5.8 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Pox_A_type_inc PF04508.12 OAP58539.1 - 0.048 13.5 1.1 1.3 9.0 0.5 2.7 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat KxDL PF10241.9 OAP58539.1 - 0.11 12.8 0.5 0.43 10.9 0.5 1.9 1 1 0 1 1 1 0 Uncharacterized conserved protein SlyX PF04102.12 OAP58539.1 - 0.19 12.4 3.2 2.7 8.7 1.5 2.5 2 0 0 2 2 2 0 SlyX bZIP_1 PF00170.21 OAP58539.1 - 0.9 9.7 10.3 1.8 8.7 10.3 1.5 1 0 0 1 1 1 0 bZIP transcription factor Acyl-CoA_dh_1 PF00441.24 OAP58540.1 - 5e-22 78.7 1.7 7.5e-22 78.2 1.7 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 OAP58540.1 - 2.4e-13 50.7 0.0 4.4e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 OAP58540.1 - 1e-10 41.7 0.0 1.9e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 OAP58540.1 - 9.9e-07 29.1 0.1 1.6e-06 28.4 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain AMP-binding PF00501.28 OAP58541.1 - 1.8e-89 300.3 0.0 2.2e-89 300.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAP58541.1 - 5.2e-15 56.2 0.2 1.2e-14 55.0 0.2 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain adh_short_C2 PF13561.6 OAP58542.1 - 6.2e-53 179.7 0.3 7.3e-53 179.5 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP58542.1 - 6.7e-42 143.2 0.1 8.6e-42 142.8 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAP58542.1 - 1.2e-05 25.3 0.4 4.4e-05 23.5 0.4 1.7 1 1 0 1 1 1 1 KR domain CLU PF13236.6 OAP58542.1 - 0.1 12.4 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Clustered mitochondria Cyclase PF04199.13 OAP58543.1 - 1.7e-16 60.7 0.5 3.2e-16 59.8 0.5 1.4 1 1 0 1 1 1 1 Putative cyclase Sugar_tr PF00083.24 OAP58544.1 - 1.3e-76 258.3 21.4 1.5e-76 258.1 21.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP58544.1 - 9.2e-20 70.9 26.2 9.2e-20 70.9 26.2 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF3493 PF11998.8 OAP58544.1 - 0.98 9.6 4.9 0.77 10.0 0.4 3.0 2 1 1 3 3 3 0 Low psii accumulation1 / Rep27 APH PF01636.23 OAP58545.1 - 2.5e-40 138.9 0.1 4.5e-40 138.1 0.0 1.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 OAP58545.1 - 0.00017 20.9 0.0 0.0031 16.8 0.0 2.2 1 1 0 1 1 1 1 Fructosamine kinase EcKinase PF02958.20 OAP58545.1 - 0.0015 18.0 0.0 0.0022 17.3 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase RIO1 PF01163.22 OAP58545.1 - 0.014 15.0 0.0 0.27 10.8 0.0 2.1 2 0 0 2 2 2 0 RIO1 family Choline_kinase PF01633.20 OAP58545.1 - 0.052 13.1 0.0 0.077 12.6 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 OAP58545.1 - 0.07 12.5 0.0 0.19 11.0 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1679 PF07914.11 OAP58545.1 - 0.2 10.4 0.0 4 6.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) BTB PF00651.31 OAP58546.1 - 8.9e-09 35.6 0.0 1.4e-08 35.0 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain EMP24_GP25L PF01105.24 OAP58547.1 - 4.1e-43 147.4 0.0 5.1e-43 147.1 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD EzrA PF06160.12 OAP58547.1 - 0.01 14.1 0.9 0.013 13.7 0.9 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA YabA PF06156.13 OAP58547.1 - 0.16 12.6 0.5 0.38 11.4 0.5 1.5 2 0 0 2 2 2 0 Initiation control protein YabA DASH_Spc34 PF08657.10 OAP58549.1 - 1.5e-40 139.6 9.8 2e-23 83.5 0.7 2.1 1 1 1 2 2 2 2 DASH complex subunit Spc34 TPR_MLP1_2 PF07926.12 OAP58549.1 - 0.022 14.8 3.0 0.16 12.0 0.4 2.4 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DASH_Spc19 PF08287.11 OAP58549.1 - 0.041 13.8 5.0 0.076 12.9 5.0 1.4 1 0 0 1 1 1 0 Spc19 zf-C4H2 PF10146.9 OAP58549.1 - 0.21 11.9 5.4 0.14 12.5 3.2 1.7 2 0 0 2 2 2 0 Zinc finger-containing protein SlyX PF04102.12 OAP58549.1 - 4.1 8.1 6.8 12 6.6 0.6 3.2 3 1 0 3 3 3 0 SlyX CCDC-167 PF15188.6 OAP58549.1 - 4.7 7.6 8.0 28 5.1 8.0 2.3 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 UPF0242 PF06785.11 OAP58549.1 - 6.9 6.7 7.5 84 3.2 7.2 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Rpn3_C PF08375.11 OAP58550.1 - 2.1e-25 88.9 1.6 2.1e-25 88.9 1.6 2.4 2 0 0 2 2 2 1 Proteasome regulatory subunit C-terminal PCI PF01399.27 OAP58550.1 - 7.2e-21 74.7 0.2 2.6e-20 72.9 0.1 2.0 2 0 0 2 2 2 1 PCI domain CSN8_PSD8_EIF3K PF10075.9 OAP58550.1 - 0.022 14.8 0.1 0.053 13.5 0.1 1.7 1 1 0 1 1 1 0 CSN8/PSMD8/EIF3K family DASH_Dam1 PF08653.10 OAP58551.1 - 2.9e-21 75.0 0.6 5.6e-21 74.1 0.6 1.5 1 0 0 1 1 1 1 DASH complex subunit Dam1 UCH PF00443.29 OAP58553.1 - 1.5e-47 162.3 0.1 2e-47 161.9 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OAP58553.1 - 1.5e-15 57.7 8.8 7.1e-14 52.1 8.8 2.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 OAP58553.1 - 0.00033 20.9 1.9 0.014 15.7 0.8 2.9 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein Ytp1 PF10355.9 OAP58554.1 - 3.5e-119 397.1 10.2 5.6e-119 396.4 10.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 OAP58554.1 - 4.6e-27 93.9 22.3 1.8e-26 91.9 9.2 3.5 4 0 0 4 4 4 2 Domain of unknown function (DUF2427) DUF3382 PF11862.8 OAP58554.1 - 0.27 11.5 6.9 3.3 8.1 0.1 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF3382) Clr5 PF14420.6 OAP58555.1 - 0.00043 20.5 0.1 0.00087 19.5 0.1 1.5 1 0 0 1 1 1 1 Clr5 domain Rhomboid PF01694.22 OAP58556.1 - 1.2e-18 67.5 6.7 1.2e-18 67.5 6.7 1.4 2 0 0 2 2 2 1 Rhomboid family Gaa1 PF04114.14 OAP58557.1 - 1.1e-161 539.3 7.3 1.3e-161 539.1 7.3 1.0 1 0 0 1 1 1 1 Gaa1-like, GPI transamidase component GFA PF04828.14 OAP58558.1 - 5.4e-16 58.7 3.9 3.1e-10 40.2 0.1 2.2 1 1 1 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme Yippee-Mis18 PF03226.14 OAP58558.1 - 0.032 14.4 0.7 0.052 13.8 0.7 1.3 1 0 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly ApbA PF02558.16 OAP58559.1 - 1.6e-29 102.5 0.0 2.5e-29 101.9 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 OAP58559.1 - 1.4e-25 90.0 0.0 6.5e-24 84.5 0.0 2.2 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA C terminal Sacchrp_dh_NADP PF03435.18 OAP58559.1 - 0.0054 17.0 0.0 0.019 15.2 0.0 2.0 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Glyco_hydro_18 PF00704.28 OAP58560.1 - 3.6e-86 289.7 0.4 4.1e-86 289.5 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 RasGAP PF00616.19 OAP58561.1 - 6.1e-56 189.4 0.0 1.3e-55 188.3 0.0 1.6 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 OAP58561.1 - 1.3e-31 109.6 0.3 1.3e-31 109.6 0.3 2.9 4 0 0 4 4 4 1 RasGAP C-terminus NYD-SP28_assoc PF14775.6 OAP58561.1 - 0.83 9.8 3.9 7.6 6.7 0.0 3.5 3 0 0 3 3 3 0 Sperm tail C-terminal domain DUF724 PF05266.14 OAP58561.1 - 3.5 7.4 6.7 7.1 6.4 2.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Beta-lactamase PF00144.24 OAP58562.1 - 2.5e-44 151.9 0.9 3.6e-44 151.4 0.9 1.2 1 0 0 1 1 1 1 Beta-lactamase Coatomer_WDAD PF04053.14 OAP58563.1 - 4.5e-145 484.1 0.0 8e-145 483.3 0.0 1.4 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.11 OAP58563.1 - 3.1e-105 352.2 0.0 4.8e-105 351.6 0.0 1.2 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.32 OAP58563.1 - 8.1e-35 118.3 14.3 3.2e-07 30.9 0.2 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat SET PF00856.28 OAP58563.1 - 5.7e-15 56.1 0.3 2.5e-14 54.0 0.0 2.2 2 0 0 2 2 2 1 SET domain ANAPC4_WD40 PF12894.7 OAP58563.1 - 6.2e-07 29.6 0.6 0.0075 16.5 0.0 5.1 3 2 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OAP58563.1 - 0.043 12.5 7.1 3.2 6.3 0.1 3.9 2 1 1 4 4 4 0 Nucleoporin Nup120/160 IPPT PF01715.17 OAP58563.1 - 0.053 13.3 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 IPP transferase Sec23_trunk PF04811.15 OAP58564.1 - 2.1e-75 253.5 0.0 2.8e-75 253.0 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 OAP58564.1 - 4.4e-30 104.3 0.1 1.1e-29 103.0 0.1 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 OAP58564.1 - 7e-24 83.6 0.0 1.7e-23 82.4 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 OAP58564.1 - 2.6e-15 56.2 2.8 4.9e-15 55.3 2.8 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 OAP58564.1 - 9.6e-11 41.4 0.0 2.4e-10 40.2 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 OAP58564.1 - 0.085 12.3 0.4 0.21 11.0 0.1 1.8 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain UL42 PF17638.2 OAP58564.1 - 0.3 11.1 6.1 0.046 13.7 1.4 1.9 2 0 0 2 2 2 0 HCMV UL42 Ribosomal_L11_N PF03946.14 OAP58565.1 - 1.2e-23 82.7 0.2 1.9e-23 82.0 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 OAP58565.1 - 2.3e-13 50.4 0.0 4.3e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Dynamin_N PF00350.23 OAP58566.1 - 1.2e-14 54.7 0.0 3.1e-13 50.1 0.0 3.0 1 1 1 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 OAP58566.1 - 3e-05 24.1 0.0 0.0038 17.3 0.0 3.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_15 PF13175.6 OAP58566.1 - 0.00053 19.8 0.3 0.0069 16.1 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_16 PF13191.6 OAP58566.1 - 0.0011 19.3 0.0 0.0011 19.3 0.0 3.0 3 1 0 3 3 3 1 AAA ATPase domain AIG1 PF04548.16 OAP58566.1 - 0.0034 16.8 0.1 0.033 13.5 0.0 2.4 2 0 0 2 2 2 1 AIG1 family AAA_22 PF13401.6 OAP58566.1 - 0.0071 16.6 0.3 1.2 9.5 0.0 3.2 3 0 0 3 3 3 1 AAA domain ABC_tran PF00005.27 OAP58566.1 - 0.0078 16.7 0.0 0.04 14.4 0.0 2.2 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 OAP58566.1 - 0.0085 16.0 0.1 0.073 13.0 0.1 2.5 2 0 0 2 2 2 1 RsgA GTPase Rx_N PF18052.1 OAP58566.1 - 0.059 13.6 4.7 1.5 9.1 0.1 3.4 2 1 0 2 2 2 0 Rx N-terminal domain AAA_18 PF13238.6 OAP58566.1 - 0.087 13.4 0.0 0.087 13.4 0.0 2.6 3 0 0 3 3 3 0 AAA domain Roc PF08477.13 OAP58566.1 - 0.13 12.5 0.0 0.43 10.8 0.0 1.9 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase FapA PF03961.13 OAP58566.1 - 0.3 9.6 7.2 0.24 10.0 2.9 2.5 3 0 0 3 3 3 0 Flagellar Assembly Protein A Cob_adeno_trans PF01923.18 OAP58566.1 - 1.3 9.2 14.4 4.4 7.4 1.0 4.7 5 0 0 5 5 5 0 Cobalamin adenosyltransferase FlaC_arch PF05377.11 OAP58566.1 - 3.2 8.2 9.0 2.2 8.8 0.1 4.7 8 0 0 8 8 6 0 Flagella accessory protein C (FlaC) Syntaxin_2 PF14523.6 OAP58566.1 - 3.3 8.1 13.3 4.1 7.8 2.2 3.9 4 0 0 4 4 3 0 Syntaxin-like protein CENP-Q PF13094.6 OAP58566.1 - 4.4 7.5 14.0 12 6.0 6.9 3.7 3 0 0 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF1664 PF07889.12 OAP58566.1 - 7.8 6.6 16.3 4.3 7.4 0.7 4.2 4 1 1 5 5 5 0 Protein of unknown function (DUF1664) Abhydrolase_3 PF07859.13 OAP58567.1 - 3.2e-30 105.6 0.2 5.1e-30 104.9 0.2 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 OAP58567.1 - 1.8e-05 23.8 0.0 2.8e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family gpD PF02925.16 OAP58567.1 - 0.04 13.9 0.0 0.074 13.0 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage scaffolding protein D DUF664 PF04978.12 OAP58567.1 - 0.054 13.9 0.4 0.1 13.0 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF664) Fungal_trans_2 PF11951.8 OAP58568.1 - 4.9e-06 25.6 0.7 8.2e-06 24.9 0.7 1.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain TUTF7_u4 PF16631.5 OAP58570.1 - 0.0073 16.9 0.8 0.045 14.4 0.7 2.2 1 1 1 2 2 2 1 Unstructured region 4 on terminal uridylyltransferase 7 MFS_1 PF07690.16 OAP58571.1 - 4.1e-23 81.9 81.5 8e-21 74.3 43.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAP58571.1 - 0.00028 19.9 32.7 0.00078 18.4 2.0 3.2 2 2 0 3 3 3 2 Sugar (and other) transporter NYN PF01936.18 OAP58572.1 - 5.4e-06 26.9 0.0 3.2e-05 24.4 0.0 2.0 1 1 0 1 1 1 1 NYN domain Lactamase_B PF00753.27 OAP58573.1 - 3.3e-20 72.9 3.8 4.3e-20 72.6 3.8 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OAP58573.1 - 7.3e-05 22.4 0.2 0.00017 21.2 0.2 1.6 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Pex2_Pex12 PF04757.14 OAP58574.1 - 8.6e-36 123.6 6.1 1.2e-35 123.2 6.1 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.6 OAP58574.1 - 0.0013 18.9 4.5 0.0029 17.7 4.5 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 OAP58574.1 - 0.016 15.3 1.3 0.052 13.6 1.3 1.9 1 1 0 1 1 1 0 RING-type zinc-finger IBN_N PF03810.19 OAP58575.1 - 6.9e-13 48.3 0.1 4.1e-12 45.8 0.1 2.4 1 0 0 1 1 1 1 Importin-beta N-terminal domain Xpo1 PF08389.12 OAP58575.1 - 0.089 12.8 2.6 0.24 11.4 0.2 3.0 2 1 1 3 3 3 0 Exportin 1-like protein Abhydrolase_6 PF12697.7 OAP58576.1 - 3.3e-15 57.3 0.1 6.6e-15 56.3 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAP58576.1 - 9.6e-15 54.9 0.0 2.1e-14 53.8 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAP58576.1 - 2.8e-12 46.4 0.0 5e-09 35.8 0.0 2.5 2 0 0 2 2 2 2 Serine aminopeptidase, S33 DSPc PF00782.20 OAP58576.1 - 5e-10 39.3 0.0 9.6e-10 38.4 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 OAP58576.1 - 0.0018 17.9 0.0 0.0029 17.2 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Ser_hydrolase PF06821.13 OAP58576.1 - 0.0022 17.9 0.0 0.0056 16.5 0.0 1.6 1 0 0 1 1 1 1 Serine hydrolase PTPlike_phytase PF14566.6 OAP58576.1 - 0.0092 16.1 0.0 0.018 15.2 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate PGAP1 PF07819.13 OAP58576.1 - 0.02 14.6 0.0 0.26 11.0 0.0 2.1 2 0 0 2 2 2 0 PGAP1-like protein DUF900 PF05990.12 OAP58576.1 - 0.034 13.7 0.0 0.059 12.9 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Y_phosphatase3 PF13350.6 OAP58576.1 - 0.077 13.0 0.0 0.24 11.3 0.0 1.7 2 0 0 2 2 2 0 Tyrosine phosphatase family LIDHydrolase PF10230.9 OAP58576.1 - 0.096 12.2 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase DSPn PF14671.6 OAP58576.1 - 0.12 12.8 0.0 0.21 12.1 0.0 1.3 1 0 0 1 1 1 0 Dual specificity protein phosphatase, N-terminal half Thioesterase PF00975.20 OAP58576.1 - 0.13 12.4 0.2 0.29 11.2 0.2 1.6 1 0 0 1 1 1 0 Thioesterase domain GatB_N PF02934.15 OAP58577.1 - 1.1e-93 313.6 0.0 1.4e-93 313.2 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 OAP58577.1 - 1.3e-20 73.8 0.0 2.1e-20 73.1 0.0 1.3 1 0 0 1 1 1 1 GatB domain p450 PF00067.22 OAP58578.1 - 1.1e-67 228.8 0.0 1.4e-67 228.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Arginase PF00491.21 OAP58579.1 - 1e-75 254.9 0.8 1.3e-75 254.5 0.8 1.1 1 0 0 1 1 1 1 Arginase family MHYT PF03707.16 OAP58580.1 - 7.2e-29 99.7 18.6 3.3e-12 46.4 0.1 4.5 4 0 0 4 4 4 3 Bacterial signalling protein N terminal repeat HATPase_c PF02518.26 OAP58580.1 - 7.1e-22 78.0 0.0 1.5e-21 77.0 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 OAP58580.1 - 1.9e-21 76.3 0.7 4.6e-21 75.1 0.7 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 OAP58580.1 - 1.2e-12 47.6 2.6 1.2e-12 47.6 0.7 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.6 OAP58580.1 - 0.027 14.4 0.0 0.093 12.6 0.0 1.9 1 0 0 1 1 1 0 GHKL domain HATPase_c_2 PF13581.6 OAP58580.1 - 0.15 12.0 0.0 0.44 10.5 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain AIM24 PF01987.17 OAP58581.1 - 1.3e-50 172.0 0.4 1.7e-50 171.7 0.4 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 eIF-5_eIF-2B PF01873.17 OAP58582.1 - 6.6e-42 142.1 0.7 1.2e-41 141.3 0.7 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.12 OAP58582.1 - 0.1 12.1 0.4 0.23 11.0 0.4 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding GET2 PF08690.10 OAP58582.1 - 0.13 11.9 6.1 0.19 11.4 6.1 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 zf-HYPF PF07503.12 OAP58582.1 - 1.6 8.6 5.1 18 5.2 3.1 2.7 2 1 1 3 3 3 0 HypF finger Arc_trans_TRASH PF08394.10 OAP58582.1 - 1.6 9.1 7.9 1.4 9.3 0.3 3.0 2 1 1 3 3 3 0 Archaeal TRASH domain DNA_binding_1 PF01035.20 OAP58585.1 - 8.3e-24 83.5 0.0 1.6e-23 82.6 0.0 1.5 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain MRC1 PF09444.10 OAP58586.1 - 1.6e-35 122.7 25.5 1.6e-35 122.7 25.5 8.3 7 3 1 8 8 8 1 MRC1-like domain AMP-binding PF00501.28 OAP58587.1 - 5.3e-77 259.2 0.1 6.7e-77 258.9 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAP58587.1 - 2.1e-13 51.0 0.3 4.4e-13 50.0 0.3 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain zf-CCHC PF00098.23 OAP58588.1 - 9.7e-53 174.0 84.7 2.6e-06 27.2 1.3 10.4 10 0 0 10 10 10 10 Zinc knuckle zf-CCHC_2 PF13696.6 OAP58588.1 - 2.6e-08 33.5 66.4 0.015 15.1 0.2 10.3 10 0 0 10 10 10 7 Zinc knuckle zf-C2H2_10 PF16588.5 OAP58588.1 - 1.2e-05 25.0 2.5 1.2e-05 25.0 2.5 7.3 7 0 0 7 7 7 4 C2H2 zinc-finger zf-CCHC_4 PF14392.6 OAP58588.1 - 1.3e-05 24.8 53.9 0.04 13.7 0.5 9.9 10 0 0 10 10 10 6 Zinc knuckle zf-CCHC_3 PF13917.6 OAP58588.1 - 2.8e-05 24.0 64.3 0.28 11.2 0.8 10.0 3 2 7 10 10 10 7 Zinc knuckle zf-CCHC_6 PF15288.6 OAP58588.1 - 0.0044 16.8 2.8 0.0044 16.8 2.8 9.2 5 4 5 10 10 10 4 Zinc knuckle adh_short PF00106.25 OAP58589.1 - 2.5e-11 43.4 0.0 3.6e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP58589.1 - 4.5e-09 36.2 0.0 5.6e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase RmlD_sub_bind PF04321.17 OAP58589.1 - 0.00089 18.4 0.0 0.0014 17.8 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain F420_oxidored PF03807.17 OAP58589.1 - 0.0099 16.4 0.1 0.03 14.9 0.1 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.21 OAP58589.1 - 0.049 13.1 0.0 0.074 12.5 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family zf-C2H2 PF00096.26 OAP58590.1 - 0.025 15.0 6.6 2.2 8.9 1.0 3.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type Not3 PF04065.15 OAP58591.1 - 9.3e-79 264.1 25.2 9.3e-79 264.1 25.2 1.9 2 0 0 2 2 2 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 OAP58591.1 - 1e-40 138.8 16.5 2.5e-40 137.6 16.5 1.7 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family DUF2373 PF10180.9 OAP58591.1 - 0.059 13.2 4.1 0.16 11.9 4.1 1.7 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2373) Frankia_peptide PF14407.6 OAP58591.1 - 0.092 12.7 0.3 0.29 11.1 0.3 1.9 1 0 0 1 1 1 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. Tyr_Deacylase PF02580.16 OAP58592.1 - 2.1e-54 184.0 0.1 2.5e-54 183.7 0.1 1.1 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase FmdA_AmdA PF03069.15 OAP58593.1 - 1.4e-175 583.6 0.0 1.6e-175 583.4 0.0 1.0 1 0 0 1 1 1 1 Acetamidase/Formamidase family Pro-kuma_activ PF09286.11 OAP58595.1 - 6.4e-39 133.5 0.2 1e-38 132.8 0.2 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 OAP58595.1 - 0.00048 19.5 0.1 0.00089 18.6 0.1 1.3 1 0 0 1 1 1 1 Subtilase family 2OG-FeII_Oxy PF03171.20 OAP58596.1 - 0.0027 18.2 0.0 0.0063 17.0 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 OAP58596.1 - 0.013 16.3 0.0 0.024 15.4 0.0 1.5 1 0 0 1 1 1 0 non-haem dioxygenase in morphine synthesis N-terminal Lactamase_B_2 PF12706.7 OAP58598.1 - 1.4e-07 31.2 0.0 3.1e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DRMBL PF07522.14 OAP58598.1 - 1.7e-07 31.4 0.0 4.3e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B PF00753.27 OAP58598.1 - 0.0012 18.9 0.1 0.004 17.2 0.0 1.9 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily RMMBL PF07521.12 OAP58598.1 - 0.013 15.4 0.0 0.038 13.9 0.0 1.8 1 0 0 1 1 1 0 Zn-dependent metallo-hydrolase RNA specificity domain NAD_binding_1 PF00175.21 OAP58599.1 - 9.1e-30 103.5 0.0 1.7e-29 102.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 OAP58599.1 - 1.8e-24 86.0 0.0 3e-24 85.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 OAP58599.1 - 2.7e-10 40.6 0.0 1.3e-05 25.3 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 OAP58599.1 - 0.039 14.2 0.0 0.086 13.1 0.0 1.6 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain HMG_box PF00505.19 OAP58600.1 - 1.2e-11 44.8 1.9 2.6e-11 43.8 1.9 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 OAP58600.1 - 2.5e-06 28.0 1.7 5.2e-06 27.0 1.7 1.6 1 0 0 1 1 1 1 HMG-box domain CDC45 PF02724.14 OAP58600.1 - 2.3 6.4 11.1 2.8 6.1 11.1 1.1 1 0 0 1 1 1 0 CDC45-like protein EBV-NA3 PF05009.12 OAP58600.1 - 3.2 7.2 6.4 6 6.3 6.3 1.6 1 1 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) Amidohydro_1 PF01979.20 OAP58601.1 - 9.5e-76 255.3 0.5 2e-75 254.3 0.5 1.5 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.20 OAP58601.1 - 3.8e-56 188.6 3.8 7.9e-56 187.6 3.8 1.6 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.20 OAP58601.1 - 1e-39 134.5 0.2 2.4e-30 104.4 0.0 2.4 1 1 1 2 2 2 2 Urease beta subunit Urease_gamma PF00547.18 OAP58601.1 - 5.1e-21 74.8 0.0 1.3e-20 73.5 0.0 1.7 1 0 0 1 1 1 1 Urease, gamma subunit Amidohydro_3 PF07969.11 OAP58601.1 - 7.5e-10 38.9 0.4 2.9e-07 30.3 0.0 2.2 1 1 1 2 2 2 2 Amidohydrolase family Abhydrolase_1 PF00561.20 OAP58604.1 - 3.2e-06 27.0 0.0 0.00088 19.0 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAP58604.1 - 1.6e-05 24.3 0.0 0.0028 17.0 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OAP58604.1 - 4.7e-05 24.1 0.0 8e-05 23.3 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 OAP58604.1 - 0.00034 20.2 0.0 0.00064 19.2 0.0 1.4 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 OAP58604.1 - 0.0016 18.4 0.0 0.0022 17.9 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.18 OAP58604.1 - 0.0036 16.9 0.0 0.34 10.4 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S15 PF02129.18 OAP58604.1 - 0.0052 16.4 0.0 0.092 12.3 0.0 2.0 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.20 OAP58604.1 - 0.048 13.3 0.0 0.074 12.7 0.0 1.2 1 0 0 1 1 1 0 Putative esterase Lipase_3 PF01764.25 OAP58604.1 - 0.075 12.9 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) SAD_SRA PF02182.17 OAP58605.1 - 3e-26 92.0 0.0 5.6e-26 91.1 0.0 1.4 1 0 0 1 1 1 1 SAD/SRA domain tRNA-synt_2 PF00152.20 OAP58606.1 - 3.5e-58 197.2 0.0 4.7e-57 193.4 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.20 OAP58606.1 - 4.9e-06 26.2 0.0 0.0013 18.2 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA_anti-codon PF01336.25 OAP58606.1 - 0.00018 21.4 0.0 0.00033 20.6 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA_anti_2 PF13742.6 OAP58606.1 - 0.017 15.3 0.0 0.029 14.6 0.0 1.4 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain zf-Tim10_DDP PF02953.15 OAP58607.1 - 4.9e-22 77.3 2.7 5.7e-22 77.1 2.7 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger CAAP1 PF15335.6 OAP58607.1 - 0.0088 16.6 0.1 0.013 16.1 0.1 1.1 1 0 0 1 1 1 1 Caspase activity and apoptosis inhibitor 1 Tom5 PF10642.9 OAP58607.1 - 0.05 13.6 0.1 0.1 12.6 0.1 1.5 1 0 0 1 1 1 0 Mitochondrial import receptor subunit or translocase Peptidase_S76 PF13611.6 OAP58607.1 - 0.15 12.4 0.0 0.18 12.1 0.0 1.2 1 0 0 1 1 1 0 Serine peptidase of plant viral polyprotein, P1 Filament PF00038.21 OAP58608.1 - 0.0015 18.2 2.4 0.0015 18.2 2.4 2.0 3 0 0 3 3 3 1 Intermediate filament protein PG_binding_1 PF01471.18 OAP58608.1 - 0.008 16.4 0.0 1.4 9.2 0.0 3.0 2 0 0 2 2 2 1 Putative peptidoglycan binding domain CEP63 PF17045.5 OAP58608.1 - 0.009 15.9 6.7 0.017 15.0 6.7 1.4 1 0 0 1 1 1 1 Centrosomal protein of 63 kDa Tropomyosin_1 PF12718.7 OAP58608.1 - 0.46 10.6 6.0 1.6 8.9 6.0 1.9 1 1 0 1 1 1 0 Tropomyosin like CENP-F_leu_zip PF10473.9 OAP58608.1 - 7.4 6.6 9.6 20 5.2 0.1 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CLTH PF10607.9 OAP58609.1 - 2.5e-28 98.8 0.0 4.8e-28 97.9 0.0 1.5 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 OAP58609.1 - 2.3e-06 27.5 2.3 5.1e-06 26.4 2.3 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 OAP58609.1 - 0.0017 18.3 2.2 0.0033 17.4 2.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Rtf2 PF04641.12 OAP58609.1 - 0.0019 17.6 0.2 0.0032 16.9 0.2 1.4 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_2 PF13639.6 OAP58609.1 - 0.012 16.0 2.9 0.022 15.1 2.9 1.5 1 0 0 1 1 1 0 Ring finger domain UxuA PF03786.13 OAP58609.1 - 0.15 10.8 0.0 0.25 10.2 0.0 1.3 1 0 0 1 1 1 0 D-mannonate dehydratase (UxuA) zf-C3HC4_2 PF13923.6 OAP58609.1 - 0.48 10.3 4.4 0.98 9.3 4.4 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) BTB PF00651.31 OAP58610.1 - 4.2e-07 30.2 0.0 9.9e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain GNT-I PF03071.15 OAP58610.1 - 0.16 10.7 0.0 0.23 10.2 0.0 1.2 1 0 0 1 1 1 0 GNT-I family Skp1_POZ PF03931.15 OAP58610.1 - 0.19 11.9 0.0 0.39 10.9 0.0 1.5 1 0 0 1 1 1 0 Skp1 family, tetramerisation domain PCI PF01399.27 OAP58611.1 - 1.8e-09 38.1 0.0 5.5e-09 36.5 0.0 1.9 2 0 0 2 2 2 1 PCI domain TPR_1 PF00515.28 OAP58611.1 - 0.0055 16.5 1.3 0.023 14.5 0.4 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 OAP58611.1 - 0.0066 16.5 0.3 0.23 11.7 0.1 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 OAP58611.1 - 0.027 14.8 0.0 0.19 12.0 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Ribosomal_L18A PF01775.17 OAP58612.1 - 4.8e-55 184.9 0.3 6.1e-55 184.5 0.3 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A Methyltransf_23 PF13489.6 OAP58613.1 - 1.5e-16 60.6 0.0 2.6e-16 59.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAP58613.1 - 1.3e-07 32.2 0.2 4.7e-06 27.2 0.1 2.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAP58613.1 - 4.1e-05 24.2 0.0 0.0024 18.6 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAP58613.1 - 0.00013 22.6 0.1 0.00083 20.0 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAP58613.1 - 0.00019 21.3 0.0 0.00072 19.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.17 OAP58613.1 - 0.0038 16.7 0.0 0.0091 15.5 0.0 1.6 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.14 OAP58613.1 - 0.015 14.9 0.0 0.029 13.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Ubie_methyltran PF01209.18 OAP58613.1 - 0.022 14.1 0.0 0.21 10.9 0.0 2.1 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Glyco_hydro_16 PF00722.21 OAP58614.1 - 4.3e-06 26.3 0.1 7.9e-06 25.5 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 PQQ_3 PF13570.6 OAP58614.1 - 7.4e-06 26.3 0.5 2.2 8.9 0.0 4.0 3 0 0 3 3 3 3 PQQ-like domain WD40 PF00400.32 OAP58614.1 - 0.00068 20.4 0.2 0.19 12.6 0.0 4.4 5 0 0 5 5 5 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAP58614.1 - 0.013 15.8 0.0 6.2 7.2 0.0 3.0 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 OAP58614.1 - 0.14 10.9 0.0 11 4.7 0.0 2.2 2 0 0 2 2 2 0 Nup133 N terminal like ABC_tran PF00005.27 OAP58615.1 - 3.4e-46 157.2 0.0 1.8e-24 86.8 0.0 3.1 3 0 0 3 3 3 2 ABC transporter ABC_membrane PF00664.23 OAP58615.1 - 2.2e-36 125.9 21.0 1.6e-25 90.3 5.5 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 OAP58615.1 - 1.6e-15 57.1 3.3 7.6e-06 25.5 0.1 4.7 4 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 OAP58615.1 - 1.2e-09 38.4 0.0 0.079 12.8 0.0 4.3 3 1 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 OAP58615.1 - 5.5e-07 30.1 0.0 0.037 14.5 0.0 3.7 3 1 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 OAP58615.1 - 1.2e-06 28.1 0.1 0.03 14.0 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 OAP58615.1 - 5.8e-06 26.6 0.6 0.093 13.0 0.0 4.0 4 0 0 4 4 4 2 AAA domain AAA_16 PF13191.6 OAP58615.1 - 7.9e-05 23.1 0.0 0.21 11.9 0.0 3.0 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 OAP58615.1 - 0.00042 20.3 0.1 0.67 9.8 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_33 PF13671.6 OAP58615.1 - 0.00054 20.1 0.1 0.059 13.5 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_5 PF07728.14 OAP58615.1 - 0.00085 19.3 0.1 6.9 6.7 0.0 3.8 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 OAP58615.1 - 0.00092 19.3 0.1 0.63 10.1 0.0 3.6 4 0 0 4 4 4 1 AAA domain AAA_30 PF13604.6 OAP58615.1 - 0.0017 18.1 0.2 9.8 5.8 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA_23 PF13476.6 OAP58615.1 - 0.0022 18.5 0.2 1.1 9.7 0.0 2.8 3 0 0 3 3 3 1 AAA domain NB-ARC PF00931.22 OAP58615.1 - 0.0034 16.6 0.9 0.47 9.6 0.0 3.2 2 2 0 2 2 2 1 NB-ARC domain AAA_7 PF12775.7 OAP58615.1 - 0.0082 15.7 0.0 0.78 9.2 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region MMR_HSR1 PF01926.23 OAP58615.1 - 0.0084 16.2 0.0 6.3 6.9 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_24 PF13479.6 OAP58615.1 - 0.013 15.2 0.1 1.3 8.7 0.0 2.6 2 1 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 OAP58615.1 - 0.013 15.4 0.8 0.27 11.1 0.0 3.0 4 0 0 4 4 3 0 ATPase domain predominantly from Archaea NACHT PF05729.12 OAP58615.1 - 0.019 14.9 0.4 3.7 7.4 0.1 3.0 2 0 0 2 2 2 0 NACHT domain RNA_helicase PF00910.22 OAP58615.1 - 0.025 15.0 0.2 23 5.4 0.0 3.4 3 0 0 3 3 3 0 RNA helicase Rad17 PF03215.15 OAP58615.1 - 0.033 14.1 0.4 0.53 10.2 0.0 2.7 3 0 0 3 3 3 0 Rad17 P-loop domain AAA_25 PF13481.6 OAP58615.1 - 0.04 13.5 2.1 1.3 8.5 0.0 3.6 4 0 0 4 4 4 0 AAA domain MeaB PF03308.16 OAP58615.1 - 0.056 12.4 0.1 0.21 10.5 0.0 1.9 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 OAP58615.1 - 0.086 12.4 0.4 1.5 8.4 0.0 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_15 PF13175.6 OAP58615.1 - 0.086 12.5 0.0 15 5.2 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain Roc PF08477.13 OAP58615.1 - 0.098 12.9 0.2 12 6.1 0.0 3.1 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase Adeno_IVa2 PF02456.15 OAP58615.1 - 0.16 10.7 0.0 0.33 9.7 0.0 1.4 1 0 0 1 1 1 0 Adenovirus IVa2 protein KAP_NTPase PF07693.14 OAP58615.1 - 0.19 10.9 0.0 4.3 6.5 0.0 2.2 2 0 0 2 2 2 0 KAP family P-loop domain NTPase_1 PF03266.15 OAP58615.1 - 0.34 10.8 3.0 54 3.7 0.2 3.3 3 0 0 3 3 3 0 NTPase DUF1118 PF06549.12 OAP58615.1 - 1.4 9.2 7.6 1.2 9.5 3.6 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1118) Iso_dh PF00180.20 OAP58616.1 - 5.4e-124 413.8 0.0 6.2e-124 413.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase IBR PF01485.21 OAP58617.1 - 9.5e-09 35.4 44.3 4.3e-05 23.7 9.5 3.8 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 OAP58617.1 - 0.0022 17.8 6.3 0.0022 17.8 6.3 4.0 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) DUF2158 PF09926.9 OAP58617.1 - 0.029 14.1 0.3 0.06 13.1 0.3 1.4 1 0 0 1 1 1 0 Uncharacterized small protein (DUF2158) PALP PF00291.25 OAP58618.1 - 1.4e-57 195.4 0.1 1.8e-57 195.0 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Hydrolase PF00702.26 OAP58621.1 - 4.6e-12 46.7 0.0 5.1e-09 36.7 0.0 3.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 OAP58621.1 - 5.6e-09 36.3 0.0 0.0001 22.4 0.0 2.8 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OAP58621.1 - 0.00033 20.7 0.0 0.0011 19.0 0.0 1.9 2 0 0 2 2 2 1 HAD-hyrolase-like HAD PF12710.7 OAP58621.1 - 0.0025 18.2 0.0 1.7 9.0 0.0 2.5 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Pkinase PF00069.25 OAP58622.1 - 4.8e-44 150.7 0.0 2e-40 138.9 0.0 3.2 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAP58622.1 - 4.8e-13 49.0 0.0 2.8e-08 33.4 0.0 3.3 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.23 OAP58622.1 - 0.00073 19.5 0.3 0.0026 17.7 0.3 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OAP58622.1 - 0.0017 17.2 0.0 0.0043 15.9 0.0 1.8 1 1 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OAP58622.1 - 0.0038 16.6 0.1 0.077 12.3 0.0 2.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 OAP58622.1 - 0.0093 15.6 0.1 0.057 13.0 0.0 2.1 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 OAP58622.1 - 0.021 14.2 0.1 1.2 8.4 0.0 2.5 3 0 0 3 3 3 0 Kinase-like DUF2724 PF10893.8 OAP58622.1 - 0.056 13.3 0.0 0.73 9.7 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2724) Cnd1_N PF12922.7 OAP58623.1 - 7.2e-60 201.6 0.4 2.2e-59 200.1 0.4 1.9 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1, N-term Cnd1 PF12717.7 OAP58623.1 - 2.1e-47 161.2 2.1 3.4e-42 144.2 0.1 3.6 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 OAP58623.1 - 1.3e-10 41.5 0.8 0.00012 22.4 0.0 4.5 3 1 1 4 4 4 3 HEAT repeats HEAT PF02985.22 OAP58623.1 - 4.8e-09 35.7 10.7 0.048 13.9 0.1 6.9 6 0 0 6 6 6 2 HEAT repeat RTP1_C1 PF10363.9 OAP58623.1 - 6.9e-06 26.2 0.0 0.0039 17.4 0.0 3.5 2 0 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 OAP58623.1 - 2.8e-05 24.5 4.0 0.16 12.5 0.1 5.9 6 0 0 6 6 6 1 HEAT-like repeat Adaptin_N PF01602.20 OAP58623.1 - 3.1e-05 22.7 11.0 0.0037 15.9 0.3 3.8 5 1 0 5 5 5 2 Adaptin N terminal region Cnd3 PF12719.7 OAP58623.1 - 6.9e-05 22.2 7.0 0.00036 19.8 0.6 3.8 3 1 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain RIX1 PF08167.12 OAP58623.1 - 0.0087 15.8 2.1 11 5.7 0.0 4.4 5 0 0 5 5 5 1 rRNA processing/ribosome biogenesis DUF573 PF04504.14 OAP58623.1 - 1.4 9.6 3.4 2.4 8.9 0.4 2.9 3 0 0 3 3 3 0 Protein of unknown function, DUF573 SKG6 PF08693.10 OAP58625.1 - 0.013 14.9 0.2 0.037 13.4 0.2 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain SOG2 PF10428.9 OAP58625.1 - 0.36 10.0 12.4 0.48 9.6 12.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein BES1_N PF05687.13 OAP58625.1 - 2.7 8.4 10.1 5.6 7.3 10.1 1.4 1 0 0 1 1 1 0 BES1/BZR1 plant transcription factor, N-terminal CDK2AP PF09806.9 OAP58625.1 - 2.9 7.9 8.9 4.5 7.3 8.9 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Fungal_trans PF04082.18 OAP58626.1 - 1.1e-19 70.5 1.4 1.4e-19 70.2 0.4 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain RcbX PF02341.15 OAP58626.1 - 0.085 13.1 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 RbcX protein zf-C2H2 PF00096.26 OAP58626.1 - 1.4 9.5 14.0 0.075 13.5 1.8 3.5 3 0 0 3 3 3 0 Zinc finger, C2H2 type Oxysterol_BP PF01237.18 OAP58627.1 - 4.5e-52 177.1 0.0 2.5e-50 171.4 0.0 2.1 1 1 0 1 1 1 1 Oxysterol-binding protein Aldedh PF00171.22 OAP58628.1 - 9e-84 281.6 0.0 1.2e-83 281.2 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1978 PF09321.10 OAP58628.1 - 0.079 12.3 0.1 0.12 11.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1978) Trehalase PF01204.18 OAP58629.1 - 4.1e-182 606.6 0.0 5.8e-182 606.1 0.0 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.11 OAP58629.1 - 4.2e-14 51.9 1.6 7.2e-14 51.2 1.6 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain FYVE PF01363.21 OAP58629.1 - 0.0022 18.1 4.4 0.0022 18.1 4.4 2.4 4 0 0 4 4 4 1 FYVE zinc finger ICL PF00463.21 OAP58630.1 - 1.2e-297 987.6 4.6 1.3e-297 987.4 4.6 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 OAP58630.1 - 1.5e-11 44.3 0.1 7.8e-11 41.9 0.0 2.0 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase DUF3197 PF11432.8 OAP58630.1 - 0.12 12.3 0.4 23 4.9 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3197) Adhesin_P1_N PF18652.1 OAP58630.1 - 0.14 12.2 0.8 0.89 9.6 0.4 2.4 2 0 0 2 2 2 0 Adhesin P1 N-terminal domain adh_short PF00106.25 OAP58631.1 - 3.9e-33 114.6 0.0 4.9e-33 114.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP58631.1 - 6.6e-22 78.2 0.0 9.7e-22 77.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP58631.1 - 5.9e-09 36.1 0.1 9.8e-09 35.4 0.1 1.3 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 OAP58631.1 - 0.0021 17.1 0.0 0.0027 16.7 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 OAP58631.1 - 0.11 11.6 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF3273 PF11677.8 OAP58632.1 - 0.14 11.4 1.2 0.23 10.7 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3273) DUF1011 PF06237.12 OAP58632.1 - 0.93 9.9 4.6 0.28 11.5 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1011) MRP-L20 PF12824.7 OAP58635.1 - 7.3e-50 169.3 7.3 8.5e-50 169.1 7.3 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Neugrin PF06413.11 OAP58635.1 - 0.003 17.6 0.1 0.0044 17.1 0.1 1.4 1 0 0 1 1 1 1 Neugrin Peptidase_M20 PF01546.28 OAP58636.1 - 3.9e-32 111.7 0.0 4.9e-32 111.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 OAP58636.1 - 1.7e-12 47.2 0.0 2.7e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 OAP58636.1 - 0.12 12.0 0.0 0.27 10.9 0.0 1.6 1 0 0 1 1 1 0 Peptidase family M28 PCMT PF01135.19 OAP58637.1 - 1.3e-65 221.1 0.0 1.5e-65 220.9 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 OAP58637.1 - 9.2e-09 35.3 0.0 1.3e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAP58637.1 - 2.6e-07 31.3 0.0 4.1e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 OAP58637.1 - 1.7e-06 28.1 0.0 2.7e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAP58637.1 - 4.3e-05 24.1 0.0 6.7e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAP58637.1 - 0.00018 21.4 0.0 0.00023 21.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OAP58637.1 - 0.0012 18.4 0.0 0.0019 17.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 OAP58637.1 - 0.0027 18.4 0.0 0.0041 17.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAP58637.1 - 0.0068 15.8 0.0 0.0091 15.3 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.13 OAP58637.1 - 0.018 14.5 0.0 0.025 14.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_24 PF13578.6 OAP58637.1 - 0.072 14.1 0.0 0.12 13.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.7 OAP58637.1 - 0.18 11.7 0.0 0.28 11.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain EF-hand_1 PF00036.32 OAP58637.1 - 0.42 10.3 2.2 0.49 10.1 0.0 2.3 2 0 0 2 2 2 0 EF hand EF-hand_5 PF13202.6 OAP58637.1 - 4 7.1 5.9 0.71 9.5 0.2 2.5 2 0 0 2 2 2 0 EF hand Cys_Met_Meta_PP PF01053.20 OAP58638.1 - 7.3e-32 110.3 0.0 1e-31 109.9 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 OAP58638.1 - 0.099 11.8 0.0 0.3 10.2 0.0 1.7 2 0 0 2 2 2 0 Aminotransferase class I and II Nrap_D5 PF17406.2 OAP58639.1 - 7.7e-56 188.3 0.3 1.2e-55 187.6 0.3 1.3 1 0 0 1 1 1 1 Nrap protein PAP/OAS1-like domain 5 Nrap_D4 PF17405.2 OAP58639.1 - 4.2e-50 170.1 0.1 1.1e-49 168.7 0.0 1.7 2 0 0 2 2 2 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D3 PF17404.2 OAP58639.1 - 3.9e-40 137.6 0.0 8.1e-40 136.5 0.0 1.5 1 0 0 1 1 1 1 Nrap protein domain 3 Nrap_D2 PF17403.2 OAP58639.1 - 2.6e-37 127.9 0.0 3.1e-34 117.9 0.0 2.4 2 0 0 2 2 2 2 Nrap protein PAP/OAS-like domain Nrap_D6 PF17407.2 OAP58639.1 - 3.9e-37 127.5 0.0 7.6e-37 126.5 0.0 1.5 1 0 0 1 1 1 1 Nrap protein domain 6 Nrap PF03813.14 OAP58639.1 - 1.5e-25 90.0 0.0 3.1e-25 89.0 0.0 1.5 1 0 0 1 1 1 1 Nrap protein domain 1 Mito_carr PF00153.27 OAP58640.1 - 6.8e-51 170.2 1.6 1.6e-19 69.6 0.2 4.0 4 0 0 4 4 4 4 Mitochondrial carrier protein SMC_N PF02463.19 OAP58641.1 - 3.3e-27 95.4 0.1 4.8e-27 94.8 0.1 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 OAP58641.1 - 1.4e-15 58.3 17.4 1.4e-15 58.3 17.4 4.8 2 2 1 3 3 3 1 AAA domain AAA_15 PF13175.6 OAP58641.1 - 4.6e-10 39.7 0.1 4.7e-09 36.4 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 OAP58641.1 - 0.00029 20.7 10.3 0.0038 17.1 0.3 3.2 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 OAP58641.1 - 0.00045 19.9 0.0 0.0009 18.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_hinge PF06470.13 OAP58641.1 - 0.0018 18.6 0.4 0.013 15.8 0.0 2.7 3 1 0 3 3 3 1 SMC proteins Flexible Hinge Domain HALZ PF02183.18 OAP58641.1 - 0.08 13.2 9.2 3.5 7.9 0.3 4.2 3 0 0 3 3 3 0 Homeobox associated leucine zipper Lectin_N PF03954.14 OAP58641.1 - 0.097 12.4 3.5 1.5 8.6 0.8 3.0 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain ABC_tran PF00005.27 OAP58641.1 - 0.16 12.5 7.8 0.97 9.9 0.2 4.0 3 2 0 3 3 3 0 ABC transporter Synaptonemal_3 PF15191.6 OAP58641.1 - 0.53 10.1 3.2 0.49 10.2 0.1 2.7 3 0 0 3 3 3 0 Synaptonemal complex central element protein 3 KNOX2 PF03791.13 OAP58641.1 - 0.66 9.5 5.8 1.3 8.5 0.2 3.1 3 0 0 3 3 3 0 KNOX2 domain FliJ PF02050.16 OAP58641.1 - 1.1 9.5 67.7 0.017 15.3 10.4 6.5 4 2 2 6 6 6 0 Flagellar FliJ protein Sec8_exocyst PF04048.14 OAP58641.1 - 1.4 8.8 11.4 1.8 8.5 0.0 5.2 2 2 3 6 6 6 0 Sec8 exocyst complex component specific domain DEAD PF00270.29 OAP58642.1 - 3.1e-42 144.3 0.0 4.5e-42 143.8 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAP58642.1 - 8.8e-29 100.1 0.9 2.6e-27 95.3 0.3 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAP58642.1 - 0.00044 20.3 0.0 0.00096 19.2 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit API5 PF05918.11 OAP58642.1 - 0.01 14.7 4.3 0.015 14.2 4.3 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) CMS1 PF14617.6 OAP58642.1 - 0.096 12.0 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit ARS2 PF04959.13 OAP58642.1 - 9.8 6.5 12.5 16 5.8 12.5 1.3 1 0 0 1 1 1 0 Arsenite-resistance protein 2 DUF1918 PF08940.11 OAP58643.1 - 0.0012 18.4 0.1 0.71 9.5 0.0 4.4 5 0 0 5 5 5 2 Domain of unknown function (DUF1918) Peptidase_C12 PF01088.21 OAP58644.1 - 8e-52 176.0 0.0 1e-51 175.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 YccV-like PF08755.11 OAP58645.1 - 5.9e-27 94.1 0.5 1.3e-26 92.9 0.0 1.9 2 0 0 2 2 2 1 Hemimethylated DNA-binding protein YccV like Transglut_core2 PF13369.6 OAP58645.1 - 3.6e-14 52.6 0.0 7.4e-14 51.6 0.0 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily F-box-like PF12937.7 OAP58645.1 - 4.8e-12 45.6 0.0 1e-11 44.6 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAP58645.1 - 5.4e-09 35.7 0.0 5.3e-08 32.5 0.0 2.4 2 0 0 2 2 2 1 F-box domain Rhodanese PF00581.20 OAP58647.1 - 0.0013 19.3 0.0 0.0036 17.8 0.0 1.8 1 1 0 1 1 1 1 Rhodanese-like domain DnaJ PF00226.31 OAP58649.1 - 3.5e-24 84.7 0.6 3.5e-24 84.7 0.6 2.2 2 0 0 2 2 2 1 DnaJ domain zf-C2H2_jaz PF12171.8 OAP58649.1 - 1e-12 48.0 15.5 2.9e-10 40.1 4.2 3.3 2 1 1 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OAP58649.1 - 1.5e-10 41.1 10.9 2.7e-09 37.1 2.2 3.2 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 OAP58649.1 - 2.2e-09 37.5 5.8 0.00076 19.8 1.2 2.5 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 OAP58649.1 - 2.6e-06 27.8 4.1 0.03 15.1 0.3 2.9 3 0 0 3 3 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 OAP58649.1 - 1.5e-05 25.2 7.5 0.015 15.8 0.8 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type RPT PF13446.6 OAP58649.1 - 0.041 13.8 0.0 0.19 11.7 0.0 2.2 1 1 0 1 1 1 0 A repeated domain in UCH-protein CpXC PF14353.6 OAP58649.1 - 0.09 12.8 5.2 0.33 11.0 0.1 2.8 3 0 0 3 3 3 0 CpXC protein Bestrophin PF01062.21 OAP58649.1 - 0.23 10.8 0.6 0.37 10.1 0.6 1.2 1 0 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel zf-C2H2_6 PF13912.6 OAP58649.1 - 0.28 11.2 8.0 2.5 8.2 0.5 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger Elf1 PF05129.13 OAP58649.1 - 1.6 8.9 5.2 1.4 9.0 1.5 2.4 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like zf-LYAR PF08790.11 OAP58649.1 - 2.1 8.3 4.7 1.6 8.7 1.0 2.4 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger SPX PF03105.19 OAP58650.1 - 8.9e-50 170.7 9.6 1.8e-49 169.7 9.6 1.5 1 1 0 1 1 1 1 SPX domain zf-C3HC4_3 PF13920.6 OAP58650.1 - 2.3e-07 30.5 7.7 4.5e-07 29.6 7.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OAP58650.1 - 1.5e-06 28.2 8.6 1.5e-06 28.2 8.6 2.4 3 0 0 3 3 2 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 OAP58650.1 - 4.1e-06 26.5 9.7 4.1e-06 26.5 9.7 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OAP58650.1 - 0.00011 22.0 10.2 0.00032 20.5 10.2 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAP58650.1 - 0.00013 21.9 8.3 0.00044 20.1 8.3 2.0 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 OAP58650.1 - 0.00016 21.6 4.2 0.00016 21.6 4.2 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 OAP58650.1 - 0.00054 20.2 11.3 0.00054 20.2 11.3 2.0 2 0 0 2 2 2 1 Ring finger domain Prok-RING_4 PF14447.6 OAP58650.1 - 0.0025 17.7 8.8 0.019 14.8 9.3 2.1 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 OAP58650.1 - 0.036 13.8 6.1 0.036 13.8 4.0 2.0 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 OAP58650.1 - 0.13 12.3 2.5 0.27 11.3 2.5 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger F-112 PF09645.10 OAP58650.1 - 0.58 10.3 4.1 0.29 11.2 0.3 2.4 2 0 0 2 2 2 0 F-112 protein TerY_C PF15616.6 OAP58650.1 - 1.1 9.3 4.2 3.2 7.9 3.3 2.0 1 1 1 2 2 2 0 TerY-C metal binding domain NOB1_Zn_bind PF08772.11 OAP58650.1 - 1.3 9.2 5.0 0.67 10.2 2.3 2.0 1 1 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like zf-P11 PF03854.14 OAP58650.1 - 1.6 8.5 8.6 1.4 8.6 3.8 2.2 1 1 1 2 2 2 0 P-11 zinc finger RecR PF02132.15 OAP58650.1 - 3 7.5 8.6 19 4.9 0.3 2.9 2 0 0 2 2 2 0 RecR protein zf-rbx1 PF12678.7 OAP58650.1 - 3.1 8.1 9.3 12 6.3 9.3 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger domain Epimerase PF01370.21 OAP58652.1 - 2.7e-11 43.4 0.0 4.1e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 OAP58652.1 - 1.6e-07 31.1 0.1 0.015 14.8 0.1 2.2 2 0 0 2 2 2 2 NmrA-like family RmlD_sub_bind PF04321.17 OAP58652.1 - 0.0055 15.8 0.0 0.047 12.8 0.0 2.0 2 0 0 2 2 2 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 OAP58652.1 - 0.02 14.3 0.0 2 7.7 0.0 2.2 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase adh_short PF00106.25 OAP58652.1 - 0.051 13.0 0.1 0.12 11.8 0.0 1.6 2 0 0 2 2 2 0 short chain dehydrogenase DUF4974 PF16344.5 OAP58652.1 - 0.078 13.0 0.0 0.24 11.4 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4974) NAD_binding_2 PF03446.15 OAP58652.1 - 0.084 13.0 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_2 PF03446.15 OAP58654.1 - 6e-34 117.5 0.2 8.2e-34 117.1 0.2 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 OAP58654.1 - 1.6e-29 102.6 0.0 2.9e-29 101.8 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 2-Hacid_dh_C PF02826.19 OAP58654.1 - 4.9e-08 32.5 0.0 8e-08 31.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 OAP58654.1 - 4.8e-05 23.9 0.4 0.00012 22.6 0.0 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.12 OAP58654.1 - 0.0013 18.3 0.0 0.0021 17.6 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain Rossmann-like PF10727.9 OAP58654.1 - 0.016 15.1 0.0 0.038 13.8 0.0 1.6 1 0 0 1 1 1 0 Rossmann-like domain SUFU PF05076.13 OAP58654.1 - 0.022 14.8 0.0 0.045 13.7 0.0 1.6 1 1 0 1 1 1 0 Suppressor of fused protein (SUFU) Polysacc_deac_2 PF04748.13 OAP58654.1 - 0.024 13.8 0.1 0.11 11.6 0.1 2.0 1 1 0 1 1 1 0 Divergent polysaccharide deacetylase AlaDh_PNT_C PF01262.21 OAP58654.1 - 0.046 13.0 0.1 0.084 12.2 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 OAP58654.1 - 0.065 13.5 0.0 0.19 12.0 0.0 1.9 1 1 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.18 OAP58654.1 - 0.067 13.1 0.0 0.2 11.5 0.0 1.9 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 OAP58655.1 - 1.7e-14 53.9 0.1 4.4e-14 52.5 0.1 1.7 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 OAP58655.1 - 1.7e-06 27.5 2.1 0.00042 19.6 0.2 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAP58655.1 - 1.1e-05 24.8 0.2 1.7e-05 24.1 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 OAP58655.1 - 6.7e-05 23.1 0.2 0.00015 21.9 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 OAP58655.1 - 0.0003 20.0 0.3 0.00054 19.2 0.3 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A DAO PF01266.24 OAP58655.1 - 0.00063 19.4 0.7 0.0083 15.7 0.3 2.2 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 OAP58655.1 - 0.036 14.6 0.4 0.81 10.3 0.3 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 OAP58655.1 - 0.051 12.9 0.2 0.074 12.4 0.2 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 OAP58655.1 - 0.066 11.9 0.5 0.13 10.9 0.4 1.5 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_4 PF01565.23 OAP58656.1 - 4.1e-28 97.9 0.0 6.5e-28 97.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.19 OAP58656.1 - 3.2e-10 40.1 0.0 4.5e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain Fungal_trans PF04082.18 OAP58657.1 - 2.3e-06 26.8 0.0 3.4e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain FMN_dh PF01070.18 OAP58658.1 - 4.5e-111 371.2 0.0 5.3e-111 371.0 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 OAP58658.1 - 1.5e-19 69.9 0.0 3.2e-19 68.8 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 OAP58658.1 - 0.0011 18.2 0.0 0.0018 17.5 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 OAP58658.1 - 0.043 12.8 0.0 0.09 11.8 0.0 1.5 1 1 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain ApbA PF02558.16 OAP58659.1 - 1.4e-32 112.4 0.0 1.9e-32 112.0 0.0 1.1 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 OAP58659.1 - 1.4e-27 96.4 0.0 2.1e-27 95.8 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal adh_short_C2 PF13561.6 OAP58660.1 - 6.5e-54 183.0 0.3 7.5e-54 182.7 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP58660.1 - 1.2e-49 168.4 0.4 1.5e-49 168.1 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAP58660.1 - 1.5e-09 38.0 1.6 3.2e-09 37.0 1.6 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 OAP58660.1 - 0.00049 19.6 0.1 0.00077 19.0 0.1 1.4 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Glyco_transf_5 PF08323.11 OAP58660.1 - 0.014 15.1 0.0 0.09 12.5 0.0 2.0 2 1 0 2 2 2 0 Starch synthase catalytic domain Glyco_transf_4 PF13439.6 OAP58660.1 - 0.11 12.5 0.0 1.8 8.6 0.0 2.5 3 0 0 3 3 3 0 Glycosyltransferase Family 4 MR_MLE_C PF13378.6 OAP58661.1 - 2.9e-55 187.2 0.1 3.8e-55 186.8 0.1 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 OAP58661.1 - 2.9e-20 72.6 0.0 7.1e-20 71.4 0.0 1.6 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Fungal_trans PF04082.18 OAP58662.1 - 3.1e-60 203.5 0.0 4.5e-60 202.9 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 OAP58662.1 - 0.00078 19.8 10.1 0.011 16.2 0.9 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type DUF5570 PF17731.1 OAP58662.1 - 0.0052 16.9 0.0 0.013 15.6 0.0 1.6 1 0 0 1 1 1 1 Family of unknown function (DUF5570) zf-H2C2_2 PF13465.6 OAP58662.1 - 0.12 12.8 4.8 0.29 11.6 1.7 2.8 2 0 0 2 2 2 0 Zinc-finger double domain Aldedh PF00171.22 OAP58663.1 - 2.1e-145 484.8 0.0 2.5e-145 484.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family AA_permease_2 PF13520.6 OAP58664.1 - 1.9e-46 158.8 56.8 1.9e-45 155.5 56.8 1.9 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAP58664.1 - 2.5e-24 85.7 40.5 3.4e-24 85.3 40.5 1.1 1 0 0 1 1 1 1 Amino acid permease Serglycin PF04360.12 OAP58665.1 - 8 6.4 6.8 14 5.6 6.4 1.5 1 1 0 1 1 1 0 Serglycin Acetyltransf_10 PF13673.7 OAP58666.1 - 2.6e-08 33.8 0.0 4.4e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAP58666.1 - 3.8e-08 33.6 0.0 5.2e-08 33.1 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OAP58666.1 - 6.2e-08 33.0 0.0 1.2e-07 32.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 OAP58666.1 - 0.011 15.8 0.0 0.078 13.1 0.0 2.2 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 OAP58666.1 - 0.12 12.5 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase MFS_1 PF07690.16 OAP58667.1 - 4.8e-34 117.8 26.9 4.8e-34 117.8 26.9 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans_2 PF11951.8 OAP58668.1 - 1.2e-09 37.5 0.0 2.1e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 OAP58669.1 - 1.1e-37 129.9 31.9 1.5e-37 129.4 31.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily NAD_binding_11 PF14833.6 OAP58670.1 - 5.4e-30 104.1 0.0 1.1e-29 103.2 0.0 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.15 OAP58670.1 - 2.2e-27 96.2 0.0 3.1e-27 95.7 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 OAP58670.1 - 0.0075 16.8 0.0 0.019 15.5 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 OAP58670.1 - 0.039 14.0 0.0 0.076 13.1 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ABM PF03992.16 OAP58671.1 - 3.5e-15 55.9 0.4 1.8e-10 40.8 0.0 2.1 2 0 0 2 2 2 2 Antibiotic biosynthesis monooxygenase Methyltransf_23 PF13489.6 OAP58672.1 - 2.4e-13 50.2 0.0 4.1e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAP58672.1 - 1.4e-10 41.8 0.0 6.8e-10 39.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAP58672.1 - 1.4e-06 28.9 0.0 3.8e-06 27.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAP58672.1 - 1.1e-05 25.3 0.0 0.0022 17.8 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAP58672.1 - 1.6e-05 25.6 0.0 0.0002 22.0 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 OAP58672.1 - 0.008 15.7 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase FtsJ PF01728.19 OAP58672.1 - 0.022 14.9 0.0 0.033 14.3 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_PK PF05891.12 OAP58672.1 - 0.076 12.5 0.1 0.14 11.7 0.1 1.3 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase CMAS PF02353.20 OAP58672.1 - 0.11 11.7 0.0 0.35 10.1 0.0 1.8 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase CheR PF01739.18 OAP58672.1 - 0.11 11.9 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain PrmA PF06325.13 OAP58672.1 - 0.12 11.8 0.0 0.51 9.7 0.0 1.9 3 0 0 3 3 3 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.18 OAP58672.1 - 0.21 10.8 0.1 2.6 7.3 0.1 2.0 1 1 0 1 1 1 0 O-methyltransferase domain HD PF01966.22 OAP58673.1 - 1.2e-06 28.7 0.0 1.8e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 HD domain CBM_1 PF00734.18 OAP58674.1 - 6.6e-08 32.4 9.3 6.6e-08 32.4 9.3 2.2 2 0 0 2 2 2 1 Fungal cellulose binding domain DPBB_1 PF03330.18 OAP58674.1 - 0.001 19.3 0.0 0.0024 18.1 0.0 1.6 1 1 0 1 1 1 1 Lytic transglycolase CAP_N PF01213.19 OAP58674.1 - 5.4 6.4 5.6 7 6.0 5.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal FAD_binding_3 PF01494.19 OAP58675.1 - 9.5e-14 51.4 0.0 2.5e-13 50.0 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAP58675.1 - 9.2e-05 22.2 1.1 0.00017 21.3 1.1 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 OAP58675.1 - 9.3e-05 21.5 0.8 0.01 14.7 0.1 2.4 2 0 0 2 2 2 2 Tryptophan halogenase Pyr_redox_2 PF07992.14 OAP58675.1 - 0.0022 17.3 0.1 0.11 11.7 0.0 2.1 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAP58675.1 - 0.0046 17.1 0.0 0.013 15.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 OAP58675.1 - 0.019 14.0 0.1 5 6.1 0.2 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 OAP58675.1 - 0.053 13.5 0.3 0.28 11.2 0.1 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 OAP58675.1 - 0.071 13.7 0.3 3.5 8.3 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase G-patch PF01585.23 OAP58676.1 - 2.5e-09 36.9 1.5 2.5e-09 36.9 1.5 2.1 2 0 0 2 2 2 1 G-patch domain R3H PF01424.22 OAP58676.1 - 8e-08 32.2 0.0 1.8e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 R3H domain G-patch_2 PF12656.7 OAP58676.1 - 0.0029 17.7 1.4 0.011 15.8 1.4 2.1 1 0 0 1 1 1 1 G-patch domain Peptidase_C54 PF03416.19 OAP58677.1 - 5.9e-98 327.7 0.0 8.3e-98 327.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 Histone PF00125.24 OAP58678.1 - 3.5e-21 75.9 0.5 4.5e-21 75.6 0.5 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 OAP58678.1 - 4.7e-05 23.6 0.0 0.00011 22.4 0.0 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 OAP58678.1 - 0.00028 21.3 0.0 0.00046 20.6 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A DUF1018 PF06252.12 OAP58678.1 - 0.056 14.4 0.4 0.077 14.0 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) RP-C PF03428.13 OAP58678.1 - 0.072 12.7 0.1 0.17 11.6 0.1 1.6 1 1 0 1 1 1 0 Replication protein C N-terminal domain Histone_H2A_C PF16211.5 OAP58679.1 - 2.9e-21 74.9 2.9 5.1e-21 74.1 2.9 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 OAP58679.1 - 1e-16 61.5 0.0 1.4e-16 61.0 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 OAP58679.1 - 9.6e-06 25.8 0.0 1.3e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Complex1_LYR PF05347.15 OAP58680.1 - 6.4e-10 38.9 1.6 1e-09 38.3 1.6 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) 2-oxoacid_dh PF00198.23 OAP58681.1 - 9.8e-81 270.6 0.4 1.3e-80 270.3 0.4 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 OAP58681.1 - 6.8e-17 61.1 1.2 1.6e-16 59.9 1.2 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 OAP58681.1 - 0.00016 21.4 0.1 0.0019 18.0 0.0 2.2 1 1 1 2 2 2 1 Biotin-lipoyl like HlyD_3 PF13437.6 OAP58681.1 - 0.00017 22.2 0.2 0.031 15.0 0.0 2.4 1 1 1 2 2 2 1 HlyD family secretion protein RnfC_N PF13375.6 OAP58681.1 - 0.00038 20.4 0.6 0.71 9.9 0.0 2.9 1 1 1 2 2 2 2 RnfC Barrel sandwich hybrid domain HlyD_D23 PF16576.5 OAP58681.1 - 0.025 13.8 0.1 0.097 11.9 0.1 1.9 1 1 0 1 1 1 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion GCV_H PF01597.19 OAP58681.1 - 0.029 14.2 0.6 0.09 12.7 0.4 1.9 1 1 0 1 1 1 0 Glycine cleavage H-protein Peptidase_M23 PF01551.22 OAP58681.1 - 0.048 13.9 0.2 6 7.1 0.1 2.6 1 1 1 2 2 2 0 Peptidase family M23 Presenilin PF01080.17 OAP58681.1 - 1.5 7.5 5.0 2.4 6.8 5.0 1.3 1 0 0 1 1 1 0 Presenilin COesterase PF00135.28 OAP58682.1 - 2.6e-55 188.3 0.0 5.9e-54 183.8 0.0 2.0 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAP58682.1 - 2.3e-05 24.3 0.0 0.19 11.6 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Sugar_tr PF00083.24 OAP58683.1 - 2e-101 340.1 21.7 2.3e-101 339.9 21.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP58683.1 - 9.4e-21 74.1 39.3 2e-20 73.0 25.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily RAMP4 PF06624.12 OAP58683.1 - 1 9.4 3.5 8.3 6.6 0.4 2.9 2 0 0 2 2 2 0 Ribosome associated membrane protein RAMP4 Phage_holin_3_2 PF04550.12 OAP58683.1 - 1.3 9.6 8.8 0.71 10.5 3.1 3.0 2 0 0 2 2 2 0 Phage holin family 2 TF_AP-2 PF03299.14 OAP58684.1 - 0.00099 19.1 2.2 0.056 13.4 0.0 2.5 2 1 1 3 3 3 2 Transcription factor AP-2 Pullulanase_Ins PF18494.1 OAP58684.1 - 0.043 14.3 0.0 27 5.3 0.0 3.2 3 0 0 3 3 3 0 Pullulanase Ins domain Acetyltransf_13 PF13880.6 OAP58685.1 - 4.4e-29 100.3 0.0 8.6e-29 99.3 0.0 1.5 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.6 OAP58685.1 - 1.7e-13 50.1 0.1 3e-13 49.3 0.1 1.5 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO MFS_1 PF07690.16 OAP58686.1 - 4.8e-39 134.3 19.9 1.5e-38 132.6 20.0 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily PLDc PF00614.22 OAP58688.1 - 1.4e-17 63.0 0.4 1.6e-08 34.4 0.3 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 OAP58688.1 - 6.5e-14 52.0 0.0 3.4e-07 30.2 0.0 3.4 2 1 0 2 2 2 2 PLD-like domain PX PF00787.24 OAP58688.1 - 3.6e-11 43.0 0.0 1.2e-10 41.4 0.0 1.9 1 0 0 1 1 1 1 PX domain ApbA PF02558.16 OAP58689.1 - 1.1e-17 64.1 0.0 1.5e-17 63.6 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.14 OAP58689.1 - 9.7e-07 28.3 0.1 1.5e-06 27.7 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAP58689.1 - 1.7e-06 27.9 0.9 2.2e-06 27.5 0.8 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 OAP58689.1 - 4.5e-06 27.1 0.2 8.3e-06 26.3 0.2 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.17 OAP58689.1 - 6.7e-06 26.6 0.0 1.5e-05 25.4 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_7 PF13241.6 OAP58689.1 - 2.7e-05 24.6 0.0 6.7e-05 23.3 0.0 1.7 2 0 0 2 2 1 1 Putative NAD(P)-binding NAD_binding_8 PF13450.6 OAP58689.1 - 0.00021 21.4 0.5 0.0004 20.6 0.5 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 OAP58689.1 - 0.00034 20.0 0.1 0.00056 19.2 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 OAP58689.1 - 0.00084 18.7 0.5 0.0012 18.1 0.5 1.2 1 0 0 1 1 1 1 FAD binding domain Shikimate_DH PF01488.20 OAP58689.1 - 0.00084 19.4 0.2 0.0013 18.8 0.2 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_2 PF03446.15 OAP58689.1 - 0.0012 19.0 0.0 0.0019 18.4 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 OAP58689.1 - 0.0015 18.4 0.1 0.0022 17.9 0.1 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 OAP58689.1 - 0.0016 18.5 0.0 0.004 17.1 0.0 1.7 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus HI0933_like PF03486.14 OAP58689.1 - 0.021 13.5 0.3 0.051 12.3 0.2 1.6 2 0 0 2 2 2 0 HI0933-like protein Rossmann-like PF10727.9 OAP58689.1 - 0.022 14.6 0.8 0.064 13.1 0.2 2.0 2 0 0 2 2 2 0 Rossmann-like domain FAD_binding_2 PF00890.24 OAP58689.1 - 0.026 13.6 0.4 0.047 12.8 0.4 1.4 1 0 0 1 1 1 0 FAD binding domain UDPG_MGDP_dh_N PF03721.14 OAP58689.1 - 0.028 14.0 0.2 0.056 13.0 0.2 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Lycopene_cycl PF05834.12 OAP58689.1 - 0.03 13.4 0.3 0.045 12.8 0.3 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein IlvN PF07991.12 OAP58689.1 - 0.038 13.6 0.1 0.061 12.9 0.1 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain XdhC_C PF13478.6 OAP58689.1 - 0.043 14.3 0.0 0.072 13.6 0.0 1.3 1 0 0 1 1 1 0 XdhC Rossmann domain ThiF PF00899.21 OAP58689.1 - 0.051 12.9 0.3 0.11 11.8 0.3 1.5 1 0 0 1 1 1 0 ThiF family GIDA PF01134.22 OAP58689.1 - 0.08 12.0 0.9 0.11 11.6 0.9 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_9 PF13454.6 OAP58689.1 - 0.081 12.9 0.1 0.22 11.5 0.1 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding TrkA_N PF02254.18 OAP58689.1 - 0.15 12.4 0.1 0.26 11.6 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain DUF1748 PF08520.10 OAP58689.1 - 0.17 11.8 0.0 0.71 9.8 0.0 2.0 2 0 0 2 2 2 0 Fungal protein of unknown function (DUF1748) Zn_clus PF00172.18 OAP58690.1 - 3.2e-05 24.0 3.1 7.2e-05 22.8 3.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 OAP58690.1 - 0.16 10.8 4.2 0.076 11.8 0.7 2.1 2 0 0 2 2 2 0 Fungal specific transcription factor domain Ras PF00071.22 OAP58691.1 - 2.4e-38 131.3 0.0 1.2e-36 125.7 0.0 2.0 1 1 0 1 1 1 1 Ras family Roc PF08477.13 OAP58691.1 - 5.3e-12 46.0 0.0 1.1e-11 44.9 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAP58691.1 - 0.00057 19.4 0.1 0.0037 16.7 0.0 2.0 1 1 1 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OAP58691.1 - 0.0038 17.3 0.0 0.0057 16.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OAP58691.1 - 0.029 13.9 0.0 0.49 9.9 0.0 2.6 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain PRK PF00485.18 OAP58691.1 - 0.088 12.5 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family DUF3176 PF11374.8 OAP58692.1 - 1e-30 106.1 0.5 3.2e-30 104.5 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) PAS_9 PF13426.7 OAP58693.1 - 8.9e-26 90.2 0.0 1.5e-16 60.5 0.0 3.6 3 0 0 3 3 3 3 PAS domain PAS_3 PF08447.12 OAP58693.1 - 2.9e-18 65.9 0.0 9.1e-11 41.9 0.0 3.6 3 0 0 3 3 3 3 PAS fold GATA PF00320.27 OAP58693.1 - 3.9e-14 52.0 7.9 3.9e-14 52.0 7.9 2.0 2 0 0 2 2 2 1 GATA zinc finger PAS PF00989.25 OAP58693.1 - 3.6e-13 49.5 0.0 0.00077 19.4 0.0 4.1 4 0 0 4 4 4 3 PAS fold PAS_11 PF14598.6 OAP58693.1 - 8.8e-09 35.5 0.0 0.00081 19.5 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.10 OAP58693.1 - 1.3e-07 31.9 0.0 0.044 14.0 0.0 3.7 3 0 0 3 3 3 2 PAS fold HUN PF08729.10 OAP58694.1 - 9.1e-08 32.0 0.0 1.9e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 HPC2 and ubinuclein domain RPAP1_C PF08620.10 OAP58695.1 - 4.4e-26 90.8 0.0 1.5e-25 89.1 0.0 1.9 2 0 0 2 2 2 1 RPAP1-like, C-terminal RPAP1_N PF08621.10 OAP58695.1 - 6.9e-14 51.3 7.6 1.4e-13 50.4 7.6 1.5 1 0 0 1 1 1 1 RPAP1-like, N-terminal FMO-like PF00743.19 OAP58696.1 - 5.5e-13 48.2 0.4 2.1e-12 46.3 0.0 2.1 3 0 0 3 3 3 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OAP58696.1 - 6.2e-09 35.5 0.0 1.4e-07 31.0 0.0 2.4 1 1 2 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAP58696.1 - 8.5e-08 32.3 0.0 3.5e-07 30.4 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAP58696.1 - 3.3e-07 29.8 0.0 0.12 11.5 0.0 3.2 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAP58696.1 - 8.8e-06 25.1 0.2 0.00019 20.7 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 OAP58696.1 - 0.041 13.5 0.0 0.14 11.7 0.0 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 OAP58696.1 - 0.11 13.1 0.1 2.8 8.5 0.0 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase adh_short PF00106.25 OAP58697.1 - 2.2e-35 121.9 0.0 4.3e-35 120.9 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP58697.1 - 1.7e-25 89.9 0.0 9.6e-25 87.5 0.0 1.8 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 OAP58697.1 - 8.5e-09 35.2 0.1 3.3e-08 33.2 0.1 1.8 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) KR PF08659.10 OAP58697.1 - 3.4e-06 27.1 0.0 1.1e-05 25.5 0.1 1.7 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 OAP58697.1 - 0.01 15.3 0.0 0.019 14.5 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NmrA PF05368.13 OAP58697.1 - 0.012 15.2 0.0 0.019 14.5 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family Proteasome PF00227.26 OAP58699.1 - 2.5e-49 167.4 0.0 3.5e-49 166.9 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 OAP58699.1 - 4.8e-13 48.5 0.3 8.3e-13 47.8 0.3 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Amidase_5 PF05382.13 OAP58699.1 - 0.16 11.9 0.0 2.9 7.8 0.0 2.2 2 0 0 2 2 2 0 Bacteriophage peptidoglycan hydrolase DUF2373 PF10180.9 OAP58700.1 - 5.5e-22 77.4 0.1 1.3e-21 76.2 0.1 1.7 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) NOT2_3_5 PF04153.18 OAP58700.1 - 0.064 13.3 0.4 0.21 11.7 0.4 1.8 1 0 0 1 1 1 0 NOT2 / NOT3 / NOT5 family Zip PF02535.22 OAP58700.1 - 9 5.4 9.0 0.88 8.7 1.7 2.1 2 0 0 2 2 2 0 ZIP Zinc transporter Asp PF00026.23 OAP58701.1 - 1e-103 347.1 0.0 1.2e-103 346.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OAP58701.1 - 6.5e-13 49.3 1.2 6.9e-11 42.7 0.6 2.6 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 OAP58701.1 - 0.00074 20.1 0.1 1.6 9.4 0.0 3.1 2 2 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 OAP58701.1 - 0.0041 17.7 0.0 8 7.1 0.0 3.3 2 1 0 2 2 2 2 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 OAP58701.1 - 0.013 15.3 0.0 0.12 12.1 0.0 2.2 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal NIF PF03031.18 OAP58702.1 - 4.8e-27 94.6 0.0 1e-26 93.6 0.0 1.5 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase BRCT PF00533.26 OAP58702.1 - 9.1e-11 42.0 0.0 2e-10 40.9 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 OAP58702.1 - 5.2e-10 39.1 0.4 1.1e-09 38.1 0.4 1.5 1 0 0 1 1 1 1 twin BRCT domain BRCT_2 PF16589.5 OAP58702.1 - 7e-05 23.2 0.0 0.0002 21.7 0.0 1.8 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 OAP58702.1 - 0.0014 18.9 0.1 0.0039 17.4 0.1 1.8 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain BRCT_3 PF18428.1 OAP58702.1 - 0.054 13.6 0.1 0.13 12.3 0.1 1.6 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain Sigma_reg_N PF13800.6 OAP58703.1 - 0.096 13.0 3.0 5.2 7.4 0.1 2.9 3 0 0 3 3 3 0 Sigma factor regulator N-terminal tRNA-synt_2 PF00152.20 OAP58705.1 - 4.2e-61 206.7 0.0 9e-61 205.7 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.20 OAP58705.1 - 0.012 15.1 0.2 4.3 6.8 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) SAP30_Sin3_bdg PF13867.6 OAP58705.1 - 0.082 13.3 0.0 0.3 11.5 0.0 2.0 1 0 0 1 1 1 0 Sin3 binding region of histone deacetylase complex subunit SAP30 DUF2434 PF10361.9 OAP58706.1 - 2.2e-99 332.2 5.2 2.8e-99 331.8 5.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2434) DUF4149 PF13664.6 OAP58706.1 - 0.027 14.8 3.0 0.17 12.2 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4149) Gti1_Pac2 PF09729.9 OAP58707.1 - 2.7e-45 154.7 0.9 1.1e-37 129.8 0.1 2.4 1 1 1 2 2 2 2 Gti1/Pac2 family HET PF06985.11 OAP58708.1 - 1.1e-29 103.7 0.4 2.3e-29 102.6 0.4 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) LVIVD PF08309.11 OAP58708.1 - 0.11 11.8 0.1 0.23 10.8 0.1 1.5 1 0 0 1 1 1 0 LVIVD repeat p450 PF00067.22 OAP58709.1 - 2.1e-30 105.9 0.0 2.6e-30 105.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 GCP_C_terminal PF04130.13 OAP58710.1 - 1.1e-94 317.4 4.8 2.6e-94 316.2 4.8 1.7 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 OAP58710.1 - 2.4e-80 270.5 0.1 3.5e-79 266.6 0.0 2.3 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal MFS_1 PF07690.16 OAP58711.1 - 1.5e-19 70.2 53.6 5.8e-13 48.5 26.6 2.9 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.13 OAP58711.1 - 8.1e-05 21.2 25.0 0.00015 20.4 25.0 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Cupin_2 PF07883.11 OAP58712.1 - 2.9e-08 33.3 0.1 0.00013 21.6 0.0 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_1 PF00190.22 OAP58712.1 - 4.3e-07 29.7 0.0 8.3e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.12 OAP58712.1 - 0.0023 17.6 0.5 0.017 14.8 0.4 2.5 1 1 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_6 PF12852.7 OAP58712.1 - 0.017 14.9 1.2 0.084 12.6 1.2 2.0 1 1 0 1 1 1 0 Cupin Pmp3 PF01679.17 OAP58713.1 - 2.8e-19 69.0 11.2 4.7e-19 68.3 11.2 1.4 1 0 0 1 1 1 1 Proteolipid membrane potential modulator RseC_MucC PF04246.12 OAP58713.1 - 0.051 13.5 0.0 0.061 13.3 0.0 1.2 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC FRG1 PF06229.12 OAP58714.1 - 1.6e-40 138.9 1.7 2.7e-40 138.1 1.7 1.4 1 0 0 1 1 1 1 FRG1-like domain zf-RING_2 PF13639.6 OAP58715.1 - 1.4e-12 47.8 5.4 2.3e-12 47.0 5.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 OAP58715.1 - 3.8e-09 36.1 3.3 6.9e-09 35.3 3.3 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 OAP58715.1 - 1.8e-08 34.0 5.0 3.2e-08 33.3 5.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAP58715.1 - 3.4e-06 26.8 3.9 5.9e-06 26.1 3.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAP58715.1 - 9.2e-06 25.5 2.9 1.4e-05 24.9 2.9 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 OAP58715.1 - 7.1e-05 22.7 4.9 0.00016 21.6 4.9 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 OAP58715.1 - 0.00014 22.1 7.7 0.00093 19.4 7.8 2.1 1 1 1 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 OAP58715.1 - 0.00099 18.9 2.3 0.0017 18.2 2.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 OAP58715.1 - 0.0033 17.5 0.4 0.0069 16.4 0.4 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger TMEM154 PF15102.6 OAP58715.1 - 0.019 14.8 0.1 0.039 13.8 0.1 1.5 1 0 0 1 1 1 0 TMEM154 protein family Prok-RING_4 PF14447.6 OAP58715.1 - 0.02 14.8 10.9 0.82 9.6 10.8 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-Nse PF11789.8 OAP58715.1 - 0.033 14.0 3.9 0.075 12.9 3.9 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.6 OAP58715.1 - 0.079 13.1 4.4 0.18 12.0 4.4 1.6 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING PspB PF06667.12 OAP58715.1 - 0.11 12.5 0.7 0.23 11.6 0.7 1.5 1 0 0 1 1 1 0 Phage shock protein B LapA_dom PF06305.11 OAP58715.1 - 0.14 12.0 1.1 0.42 10.5 1.1 1.8 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain PHD PF00628.29 OAP58715.1 - 0.16 11.9 2.4 0.27 11.2 2.4 1.4 1 0 0 1 1 1 0 PHD-finger zf-RING_4 PF14570.6 OAP58715.1 - 0.21 11.4 3.8 0.37 10.6 3.8 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Baculo_11_kDa PF06143.11 OAP58715.1 - 0.24 11.0 1.6 0.47 10.1 1.6 1.4 1 0 0 1 1 1 0 Baculovirus 11 kDa family FANCL_C PF11793.8 OAP58715.1 - 0.25 11.5 1.8 0.71 10.1 1.8 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain SIT PF15330.6 OAP58715.1 - 0.26 11.8 1.0 0.55 10.7 1.0 1.5 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT zf-RING-like PF08746.11 OAP58715.1 - 0.28 11.5 1.8 0.59 10.5 1.8 1.6 1 1 0 1 1 1 0 RING-like domain DUF4381 PF14316.6 OAP58715.1 - 2.6 8.3 5.8 2.8 8.2 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) zf-C3H2C3 PF17122.5 OAP58715.1 - 4.3 7.5 8.2 0.17 12.0 1.6 2.1 2 0 0 2 2 1 0 Zinc-finger Ada3 PF10198.9 OAP58716.1 - 6.8e-45 152.4 0.0 6.8e-45 152.4 0.0 2.5 2 0 0 2 2 2 1 Histone acetyltransferases subunit 3 CSTF2_hinge PF14327.6 OAP58716.1 - 0.18 12.3 0.0 0.44 11.0 0.0 1.6 1 0 0 1 1 1 0 Hinge domain of cleavage stimulation factor subunit 2 Effector_1 PF04518.12 OAP58716.1 - 0.48 9.5 2.0 0.75 8.8 2.0 1.2 1 0 0 1 1 1 0 Effector from type III secretion system Ndc1_Nup PF09531.10 OAP58716.1 - 5.4 5.6 7.7 8.2 5.0 7.7 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Pkinase PF00069.25 OAP58717.1 - 4.6e-16 59.0 0.0 3.9e-10 39.5 0.0 3.0 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAP58717.1 - 7.6e-10 38.5 0.0 4.4e-08 32.7 0.0 3.3 2 1 0 2 2 2 1 Protein tyrosine kinase p450 PF00067.22 OAP58718.1 - 1.2e-47 162.7 0.0 1.7e-47 162.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DMSP_lyase PF16867.5 OAP58719.1 - 0.16 11.6 2.5 0.15 11.7 0.3 2.0 2 0 0 2 2 2 0 Dimethlysulfonioproprionate lyase COQ7 PF03232.13 OAP58720.1 - 2e-70 236.0 0.1 2.6e-70 235.6 0.1 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.17 OAP58720.1 - 2.3e-06 28.1 0.0 8.2e-06 26.3 0.0 1.8 1 1 0 1 1 1 1 Rubrerythrin Crr6 PF08847.11 OAP58720.1 - 0.029 14.0 0.0 0.068 12.8 0.0 1.6 1 1 1 2 2 2 0 Chlororespiratory reduction 6 Plus-3 PF03126.18 OAP58721.1 - 1.1e-25 90.3 0.0 6.1e-25 87.9 0.0 2.1 2 0 0 2 2 2 1 Plus-3 domain Aldo_ket_red PF00248.21 OAP58723.1 - 2.6e-47 161.4 0.0 3.2e-47 161.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Pro_isomerase PF00160.21 OAP58727.1 - 4.3e-34 118.1 0.1 9e-34 117.0 0.1 1.6 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_2 PF07719.17 OAP58727.1 - 5.1e-09 35.6 9.5 4.1e-07 29.6 0.5 3.8 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 OAP58727.1 - 9.8e-09 34.7 7.7 1.9e-06 27.4 0.1 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 OAP58727.1 - 6.8e-07 29.5 3.9 7.3e-06 26.2 0.4 2.6 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 OAP58727.1 - 4e-06 26.4 6.6 0.0082 15.8 0.3 3.1 2 1 0 2 2 2 2 TPR repeat TPR_8 PF13181.6 OAP58727.1 - 1.4e-05 24.9 7.2 7.9e-05 22.6 0.1 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 OAP58727.1 - 0.00013 22.4 4.5 0.00077 20.1 2.3 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 OAP58727.1 - 0.00035 20.7 1.8 0.005 17.0 0.5 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 OAP58727.1 - 0.011 16.3 10.0 0.019 15.6 2.5 2.9 1 1 0 2 2 2 0 Tetratricopeptide repeat TPR_15 PF13429.6 OAP58727.1 - 0.012 14.8 6.2 0.16 11.2 1.0 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 OAP58727.1 - 0.11 13.1 0.8 0.11 13.1 0.8 3.0 1 1 0 2 2 2 0 Tetratricopeptide repeat Vta1_C PF18097.1 OAP58727.1 - 0.16 11.7 1.1 27 4.6 0.0 3.3 3 1 1 4 4 4 0 Vta1 C-terminal domain TPR_6 PF13174.6 OAP58727.1 - 0.61 10.8 8.4 0.31 11.8 0.4 3.6 3 1 1 4 4 4 0 Tetratricopeptide repeat NAD_binding_8 PF13450.6 OAP58728.1 - 6.4e-07 29.5 0.1 6.5e-06 26.3 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain AA_permease PF00324.21 OAP58729.1 - 8.6e-136 453.3 40.1 9.8e-136 453.1 40.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAP58729.1 - 3.3e-37 128.4 45.3 4.5e-37 127.9 45.3 1.2 1 0 0 1 1 1 1 Amino acid permease TPR_12 PF13424.6 OAP58730.1 - 4.5e-10 39.7 26.0 0.054 13.8 0.1 10.1 9 2 1 10 10 10 4 Tetratricopeptide repeat NACHT PF05729.12 OAP58730.1 - 5.5e-10 39.4 0.0 1.6e-09 37.9 0.0 1.9 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 OAP58730.1 - 1.5e-07 31.9 0.0 7.6e-07 29.7 0.0 2.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OAP58730.1 - 1.3e-05 25.5 1.4 5.2e-05 23.5 0.0 2.9 3 0 0 3 3 3 1 AAA domain TPR_19 PF14559.6 OAP58730.1 - 4.3e-05 23.9 0.5 1.7 9.2 0.0 5.2 4 1 0 4 4 4 2 Tetratricopeptide repeat AAA PF00004.29 OAP58730.1 - 0.032 14.6 0.2 0.38 11.2 0.0 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 OAP58730.1 - 0.12 12.9 1.3 2.2 8.8 0.1 3.7 3 1 0 3 3 3 0 AAA domain ACT PF01842.25 OAP58730.1 - 0.18 11.6 2.3 2 8.3 0.1 3.3 3 0 0 3 3 3 0 ACT domain TPR_7 PF13176.6 OAP58730.1 - 0.25 11.5 6.6 14 6.0 0.0 5.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 OAP58730.1 - 0.65 9.9 8.3 10 6.2 0.0 6.2 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_2 PF07719.17 OAP58730.1 - 0.89 9.8 6.9 21 5.6 0.1 4.9 6 0 0 6 6 5 0 Tetratricopeptide repeat Kelch_4 PF13418.6 OAP58731.1 - 1.3e-23 82.8 7.8 4e-10 39.5 0.1 6.9 6 1 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.6 OAP58731.1 - 4.3e-20 71.5 3.5 0.00019 21.6 0.0 7.1 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_1 PF01344.25 OAP58731.1 - 1.2e-14 53.5 0.6 0.00043 19.8 0.0 5.8 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.6 OAP58731.1 - 7.3e-13 48.3 3.2 0.0001 22.4 0.0 5.4 5 1 1 6 6 6 4 Kelch motif Kelch_2 PF07646.15 OAP58731.1 - 1.4e-10 40.7 5.9 3.7e-05 23.5 0.1 5.4 6 1 0 6 6 6 3 Kelch motif Kelch_5 PF13854.6 OAP58731.1 - 1.1e-07 31.6 0.4 0.44 10.6 0.0 5.3 5 0 0 5 5 5 2 Kelch motif adh_short PF00106.25 OAP58732.1 - 2.2e-36 125.2 0.0 3.1e-36 124.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP58732.1 - 3.1e-36 125.1 0.4 4.1e-36 124.7 0.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP58732.1 - 2.8e-06 27.3 0.1 5.5e-06 26.4 0.1 1.4 1 0 0 1 1 1 1 KR domain DUF664 PF04978.12 OAP58732.1 - 0.11 12.9 0.2 0.21 12.0 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF664) MIF4G PF02854.19 OAP58733.1 - 7.4e-22 78.0 4.9 1.2e-21 77.4 4.9 1.3 1 0 0 1 1 1 1 MIF4G domain MA3 PF02847.17 OAP58733.1 - 2.4e-19 69.4 0.2 1.1e-18 67.3 0.1 2.2 2 0 0 2 2 2 1 MA3 domain SRP14 PF02290.15 OAP58734.1 - 1.3e-25 89.5 0.2 1.3e-25 89.5 0.2 1.8 2 1 0 2 2 2 1 Signal recognition particle 14kD protein DUF1934 PF09148.10 OAP58734.1 - 0.11 12.6 0.5 0.15 12.1 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1934) RRP14 PF15459.6 OAP58734.1 - 8.5 7.1 13.8 14 6.3 0.4 2.3 2 0 0 2 2 2 0 60S ribosome biogenesis protein Rrp14 Inp1 PF12634.7 OAP58735.1 - 3.3e-37 127.5 0.0 1.1e-36 125.9 0.0 1.9 1 0 0 1 1 1 1 Inheritance of peroxisomes protein 1 p450 PF00067.22 OAP58737.1 - 4.1e-66 223.6 0.0 5.1e-66 223.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PAP2_3 PF14378.6 OAP58738.1 - 0.0016 18.2 0.4 0.0016 18.1 0.4 1.2 1 0 0 1 1 1 1 PAP2 superfamily adh_short_C2 PF13561.6 OAP58741.1 - 2.7e-47 161.3 0.0 3.1e-47 161.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP58741.1 - 4.5e-41 140.5 0.2 5.3e-41 140.2 0.2 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAP58741.1 - 3.6e-10 40.0 0.0 6.4e-10 39.2 0.0 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 OAP58741.1 - 4.1e-06 26.4 0.0 3.3e-05 23.5 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 OAP58741.1 - 0.0015 17.7 0.0 0.0023 17.1 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 OAP58741.1 - 0.0032 16.9 0.0 0.012 15.1 0.0 1.8 1 1 1 2 2 2 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 OAP58741.1 - 0.022 13.9 0.0 0.03 13.5 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 OAP58741.1 - 0.036 13.1 0.2 0.068 12.2 0.0 1.5 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family EI24 PF07264.11 OAP58743.1 - 5.3e-12 46.4 0.1 1.5e-10 41.6 0.1 2.1 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) 3HCDH_N PF02737.18 OAP58744.1 - 1.5e-54 184.7 1.8 2e-54 184.2 1.8 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 OAP58744.1 - 1.1e-33 115.7 0.0 3.9e-33 113.9 0.0 2.0 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 OAP58744.1 - 9.3e-05 22.6 0.8 0.00047 20.4 0.8 2.1 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Sacchrp_dh_NADP PF03435.18 OAP58744.1 - 0.0013 18.9 0.4 0.0037 17.5 0.4 1.8 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain 2-Hacid_dh_C PF02826.19 OAP58744.1 - 0.0018 17.6 0.6 0.081 12.3 0.1 2.2 1 1 1 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 OAP58744.1 - 0.0046 16.5 0.7 0.061 12.9 0.5 2.1 1 1 1 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox_2 PF07992.14 OAP58744.1 - 0.0057 15.9 0.0 0.0076 15.5 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAP58744.1 - 0.067 12.8 0.2 0.1 12.1 0.2 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_Gly3P_dh_N PF01210.23 OAP58744.1 - 0.08 12.9 0.1 0.12 12.3 0.1 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox PF00070.27 OAP58744.1 - 0.13 12.9 0.0 0.27 11.8 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 OAP58744.1 - 0.17 12.1 0.9 1.1 9.5 0.1 2.5 3 0 0 3 3 3 0 TrkA-N domain F420_oxidored PF03807.17 OAP58744.1 - 0.5 11.0 2.7 3.3 8.4 2.1 2.5 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent TIMELESS PF04821.14 OAP58745.1 - 2e-84 283.2 0.0 5.3e-84 281.7 0.0 1.8 1 0 0 1 1 1 1 Timeless protein TIMELESS_C PF05029.13 OAP58745.1 - 9.3e-26 91.1 58.0 1.1e-25 90.9 48.4 4.5 2 1 0 2 2 2 1 Timeless protein C terminal region LPP20 PF02169.16 OAP58745.1 - 1 9.7 3.6 0.92 9.9 1.2 2.2 2 0 0 2 2 2 0 LPP20 lipoprotein Amidohydro_1 PF01979.20 OAP58746.1 - 6.4e-69 232.9 0.0 7.5e-69 232.7 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 OAP58746.1 - 3.3e-08 33.4 0.3 0.00019 21.0 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family SGIII PF15467.6 OAP58746.1 - 0.0099 15.2 0.0 0.014 14.7 0.0 1.1 1 0 0 1 1 1 1 Secretogranin-3 cNMP_binding PF00027.29 OAP58747.1 - 2.8e-29 101.0 2.0 9.6e-18 64.1 0.0 5.7 6 0 0 6 6 6 4 Cyclic nucleotide-binding domain Patatin PF01734.22 OAP58747.1 - 2.2e-17 64.0 5.0 2.2e-16 60.7 5.0 2.7 1 1 0 1 1 1 1 Patatin-like phospholipase ADH_N PF08240.12 OAP58748.1 - 2.9e-26 91.5 2.6 2.9e-26 91.5 2.6 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAP58748.1 - 4.1e-21 75.3 0.0 6.1e-21 74.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAP58748.1 - 4.2e-08 34.3 0.0 9.4e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 OAP58748.1 - 1.7e-05 24.4 0.0 2.9e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus 2-Hacid_dh_C PF02826.19 OAP58748.1 - 0.026 13.9 0.1 0.057 12.8 0.0 1.5 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 OAP58748.1 - 0.044 14.2 0.0 0.078 13.4 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding ADH_N_assoc PF13823.6 OAP58748.1 - 0.095 12.7 2.3 0.1 12.6 0.0 2.3 2 0 0 2 2 2 0 Alcohol dehydrogenase GroES-associated FAD_binding_3 PF01494.19 OAP58748.1 - 0.16 11.2 0.2 0.22 10.7 0.2 1.1 1 0 0 1 1 1 0 FAD binding domain GGACT PF06094.12 OAP58750.1 - 7.6e-09 36.2 0.5 3.7e-08 34.0 0.0 2.1 2 0 0 2 2 2 1 Gamma-glutamyl cyclotransferase, AIG2-like RNase_H PF00075.24 OAP58751.1 - 2.6e-14 53.6 0.0 3.9e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 RNase H Propep_M14 PF02244.16 OAP58751.1 - 0.16 12.4 0.0 0.39 11.2 0.0 1.6 1 0 0 1 1 1 0 Carboxypeptidase activation peptide Ribosomal_S2 PF00318.20 OAP58752.1 - 4.3e-65 218.9 0.1 3.2e-64 216.1 0.1 2.0 1 1 0 1 1 1 1 Ribosomal protein S2 DUF2528 PF10800.8 OAP58752.1 - 0.034 14.7 0.0 0.078 13.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2528) SKG6 PF08693.10 OAP58753.1 - 0.11 11.9 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Stevor PF17410.2 OAP58753.1 - 0.18 11.3 0.6 0.27 10.7 0.6 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame GPP34 PF05719.11 OAP58756.1 - 2.6e-68 230.1 0.3 3.4e-68 229.7 0.3 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) Amidohydro_2 PF04909.14 OAP58757.1 - 8.6e-27 94.7 1.2 8.6e-26 91.4 1.2 2.0 1 1 0 1 1 1 1 Amidohydrolase Asp PF00026.23 OAP58758.1 - 1e-61 209.1 3.0 1.3e-61 208.7 3.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OAP58758.1 - 1.8e-09 38.1 0.5 1.8e-07 31.6 0.5 2.8 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 OAP58758.1 - 1.3e-05 25.7 0.7 2.1 9.0 0.1 3.8 3 0 0 3 3 3 3 Aspartyl protease gag-asp_proteas PF13975.6 OAP58758.1 - 0.00017 22.1 0.1 0.59 10.7 0.0 3.8 3 1 0 3 3 3 2 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 OAP58758.1 - 0.042 13.6 0.0 0.098 12.4 0.0 1.7 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal Sterol_MT_C PF08498.10 OAP58759.1 - 6.7e-28 96.8 0.3 1.2e-27 96.0 0.3 1.5 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 OAP58759.1 - 3.9e-18 65.9 0.0 7.2e-18 65.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAP58759.1 - 8e-17 61.7 0.0 1.5e-16 60.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAP58759.1 - 3.5e-15 56.1 0.0 1.2e-14 54.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.20 OAP58759.1 - 1.2e-10 41.1 0.1 1.9e-10 40.5 0.1 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 OAP58759.1 - 6.9e-10 39.0 0.0 1.1e-09 38.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAP58759.1 - 1.8e-09 38.2 0.0 3.8e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAP58759.1 - 1.2e-07 31.3 0.0 2e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_29 PF03141.16 OAP58759.1 - 5.3e-05 22.0 0.0 7.2e-05 21.5 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PrmA PF06325.13 OAP58759.1 - 0.00039 19.9 0.0 0.00089 18.7 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.19 OAP58759.1 - 0.0015 18.3 0.0 0.0024 17.7 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_15 PF09445.10 OAP58759.1 - 0.0023 17.5 0.0 0.0038 16.8 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase RrnaAD PF00398.20 OAP58759.1 - 0.0079 15.3 0.0 0.014 14.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase MTS PF05175.14 OAP58759.1 - 0.021 14.4 0.0 0.044 13.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain MetW PF07021.12 OAP58759.1 - 0.11 12.0 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.6 OAP58759.1 - 0.13 12.3 0.1 0.43 10.5 0.0 1.8 1 1 1 2 2 2 0 Methyltransferase domain RRM_1 PF00076.22 OAP58760.1 - 4e-09 36.2 0.0 8e-09 35.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 OAP58760.1 - 0.0068 16.4 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Complex1_LYR PF05347.15 OAP58761.1 - 0.0029 17.6 0.1 0.0046 17.0 0.1 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) RAC_head PF16717.5 OAP58762.1 - 6.1e-29 100.9 6.7 6.1e-29 100.9 6.7 3.5 4 1 0 4 4 4 1 Ribosome-associated complex head domain DnaJ PF00226.31 OAP58762.1 - 6.8e-20 71.0 2.0 3e-19 68.9 2.0 2.2 1 0 0 1 1 1 1 DnaJ domain Endonuc_Holl PF10107.9 OAP58762.1 - 1.5 8.6 17.3 2.2 8.1 16.3 1.9 1 1 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase V_ATPase_I PF01496.19 OAP58762.1 - 3.7 5.4 11.3 5.6 4.7 11.3 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Fungal_trans PF04082.18 OAP58763.1 - 3.9e-27 95.0 0.2 6.8e-27 94.1 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Gpr1_Fun34_YaaH PF01184.19 OAP58764.1 - 7.6e-85 283.7 19.9 8.7e-85 283.5 19.9 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family zf-LITAF-like PF10601.9 OAP58764.1 - 0.031 14.5 0.2 0.082 13.2 0.2 1.7 1 0 0 1 1 1 0 LITAF-like zinc ribbon domain ADH_zinc_N PF00107.26 OAP58765.1 - 7.6e-20 71.2 0.5 1.4e-19 70.4 0.5 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAP58765.1 - 0.00019 21.3 0.0 0.00041 20.2 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 OAP58765.1 - 0.00027 20.5 0.2 0.00039 20.0 0.2 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 OAP58765.1 - 0.00075 20.6 0.0 0.0013 19.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_2 PF03446.15 OAP58766.1 - 3.5e-37 128.0 0.7 5e-37 127.5 0.7 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 OAP58766.1 - 2.3e-27 95.6 0.0 4.3e-27 94.8 0.0 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase MetW PF07021.12 OAP58766.1 - 0.068 12.8 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW CoA_transf_3 PF02515.17 OAP58767.1 - 2e-38 132.5 0.0 8e-38 130.5 0.0 1.8 2 0 0 2 2 2 1 CoA-transferase family III Aldedh PF00171.22 OAP58768.1 - 8.9e-136 453.1 0.1 1e-135 452.9 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Ada_Zn_binding PF02805.16 OAP58769.1 - 2.6e-28 97.8 1.4 3.8e-28 97.3 1.4 1.2 1 0 0 1 1 1 1 Metal binding domain of Ada HTH_18 PF12833.7 OAP58769.1 - 0.011 16.0 0.0 0.022 15.0 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_AraC PF00165.23 OAP58769.1 - 0.016 15.3 0.0 0.036 14.2 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix proteins, AraC family FlhC PF05280.11 OAP58769.1 - 0.18 11.5 0.2 0.58 9.9 0.1 1.8 1 1 1 2 2 2 0 Flagellar transcriptional activator (FlhC) Flavin_Reduct PF01613.18 OAP58770.1 - 3.1e-11 43.6 0.0 4.3e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 Flavin reductase like domain Putative_PNPOx PF01243.20 OAP58770.1 - 0.0024 18.0 0.0 0.0041 17.3 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF447 PF04289.12 OAP58770.1 - 0.024 14.4 0.0 0.051 13.3 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF447) GST_N PF02798.20 OAP58771.1 - 8.5e-13 48.5 0.0 7.7e-12 45.4 0.0 2.4 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OAP58771.1 - 1.2e-11 44.6 0.1 2.8e-11 43.5 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 OAP58771.1 - 5.3e-10 39.6 0.0 1.4e-09 38.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OAP58771.1 - 2.7e-07 30.8 0.0 8e-07 29.3 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 OAP58771.1 - 2.6e-06 27.5 0.0 8.6e-06 25.9 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OAP58771.1 - 8.5e-06 25.7 0.1 2e-05 24.5 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain FAD_binding_4 PF01565.23 OAP58772.1 - 1.2e-25 89.8 0.0 2e-25 89.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.19 OAP58772.1 - 1.2e-11 44.8 1.1 1.3e-11 44.7 0.0 1.6 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain FSH1 PF03959.13 OAP58773.1 - 4e-29 101.8 0.0 5.2e-29 101.4 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Imm74 PF15603.6 OAP58773.1 - 0.11 12.7 0.5 0.22 11.7 0.5 1.4 1 0 0 1 1 1 0 Immunity protein 74 Abhydrolase_1 PF00561.20 OAP58773.1 - 0.33 10.6 0.9 0.83 9.2 0.9 1.7 1 1 0 1 1 1 0 alpha/beta hydrolase fold NB-ARC PF00931.22 OAP58774.1 - 1e-08 34.7 0.0 1.6e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.6 OAP58774.1 - 0.00012 22.4 0.0 0.00053 20.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OAP58774.1 - 0.00022 21.6 0.0 0.00048 20.6 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 OAP58774.1 - 0.00088 19.3 0.0 0.01 15.9 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 OAP58774.1 - 0.03 14.7 0.0 0.057 13.9 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 OAP58774.1 - 0.15 12.3 0.0 0.33 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 OAP58774.1 - 0.16 11.4 0.0 0.29 10.5 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Rad17 PF03215.15 OAP58774.1 - 0.18 11.7 0.0 0.49 10.3 0.0 1.7 2 0 0 2 2 2 0 Rad17 P-loop domain DUF676 PF05057.14 OAP58775.1 - 6.2e-06 25.9 0.0 1e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 OAP58775.1 - 0.0001 23.0 0.0 0.00014 22.6 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 OAP58775.1 - 0.0005 19.9 0.0 0.00085 19.1 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein ECH_1 PF00378.20 OAP58776.1 - 7.3e-40 136.8 0.0 1.4e-39 135.9 0.0 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAP58776.1 - 8.9e-28 97.7 0.0 1e-27 97.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase DUF4440 PF14534.6 OAP58777.1 - 4.6e-08 33.4 0.0 6e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) CARD PF00619.21 OAP58777.1 - 0.11 12.5 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Caspase recruitment domain CsbD PF05532.12 OAP58778.1 - 0.00031 20.6 27.5 0.0067 16.3 8.1 2.4 1 1 1 2 2 2 2 CsbD-like LEA_4 PF02987.16 OAP58778.1 - 0.23 11.6 16.1 0.66 10.1 0.2 3.0 3 1 0 3 3 3 0 Late embryogenesis abundant protein DnaJ PF00226.31 OAP58779.1 - 1.8e-10 40.8 0.5 3.4e-10 39.9 0.5 1.5 1 0 0 1 1 1 1 DnaJ domain Tannase PF07519.11 OAP58780.1 - 3.8e-95 319.5 0.2 4.6e-95 319.3 0.2 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Sugar_tr PF00083.24 OAP58781.1 - 1.2e-54 185.9 9.9 9.8e-38 130.2 0.1 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 OAP58781.1 - 1e-19 70.7 26.1 4e-16 58.9 11.8 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 OAP58781.1 - 2.8e-05 22.8 3.4 2.8e-05 22.8 3.4 3.1 2 1 1 3 3 3 3 MFS/sugar transport protein PUCC PF03209.15 OAP58781.1 - 0.0003 19.9 3.2 0.0003 19.9 3.2 1.7 2 0 0 2 2 2 1 PUCC protein TRI12 PF06609.13 OAP58781.1 - 0.001 17.6 1.2 0.001 17.6 1.2 1.8 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF1485 PF07364.12 OAP58782.1 - 8.5e-102 340.3 0.2 1.1e-101 340.0 0.2 1.1 1 0 0 1 1 1 1 Metallopeptidase family M81 MlrC_C PF07171.12 OAP58782.1 - 2.7e-58 197.1 0.2 4e-58 196.5 0.2 1.3 1 0 0 1 1 1 1 MlrC C-terminus 2-Hacid_dh_C PF02826.19 OAP58783.1 - 2.5e-45 154.0 0.0 3.7e-45 153.5 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 OAP58783.1 - 0.0068 16.1 0.0 0.018 14.7 0.0 1.8 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Aminotran_5 PF00266.19 OAP58784.1 - 5e-27 94.8 0.0 7e-27 94.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V ADH_N PF08240.12 OAP58785.1 - 2.2e-26 91.9 1.0 3.2e-26 91.4 0.3 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAP58785.1 - 1.1e-16 61.1 0.0 1.9e-16 60.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 OAP58785.1 - 0.019 14.3 0.1 0.029 13.7 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain MIT PF04212.18 OAP58786.1 - 5.3e-12 45.6 1.5 1.1e-11 44.6 1.5 1.6 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain AAA_14 PF13173.6 OAP58786.1 - 0.06 13.4 0.1 3.5 7.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain Cupin_1 PF00190.22 OAP58787.1 - 4.8e-17 62.0 1.3 5.9e-17 61.7 1.3 1.1 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 OAP58787.1 - 0.00061 19.4 0.0 0.001 18.7 0.0 1.3 1 0 0 1 1 1 1 Cupin domain AA_kinase PF00696.28 OAP58788.1 - 1.8e-26 93.2 0.5 2.5e-26 92.8 0.5 1.2 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.20 OAP58788.1 - 6.1e-17 61.3 0.2 1.7e-16 59.9 0.2 1.8 1 1 0 1 1 1 1 PUA domain Nucleotid_trans PF03407.16 OAP58788.1 - 0.062 13.3 0.0 0.098 12.6 0.0 1.2 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase CPSase_L_D2 PF02786.17 OAP58789.1 - 1e-54 185.3 0.0 1.6e-54 184.6 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Carboxyl_trans PF01039.22 OAP58789.1 - 2.7e-46 158.3 0.0 1.8e-38 132.5 0.0 2.3 2 0 0 2 2 2 2 Carboxyl transferase domain Biotin_carb_N PF00289.22 OAP58789.1 - 1.3e-31 109.4 0.0 1.3e-30 106.2 0.0 2.5 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 OAP58789.1 - 2e-22 79.4 0.0 1.3e-21 76.7 0.0 2.2 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 OAP58789.1 - 1.4e-15 56.8 0.8 9.5e-15 54.2 0.8 2.3 2 0 0 2 2 2 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 OAP58789.1 - 9.9e-08 31.7 5.7 0.00011 22.0 1.1 2.7 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp_3 PF02655.14 OAP58789.1 - 1.7e-05 24.9 0.0 3.7e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.6 OAP58789.1 - 0.0003 21.4 0.3 0.65 10.7 0.0 2.7 2 0 0 2 2 2 2 HlyD family secretion protein HlyD_D23 PF16576.5 OAP58789.1 - 0.00093 18.5 1.1 0.76 9.0 0.1 2.3 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion ECH_1 PF00378.20 OAP58789.1 - 0.0012 18.3 0.3 0.0023 17.3 0.3 1.4 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ATPgrasp_ST PF14397.6 OAP58789.1 - 0.0015 17.9 0.0 0.0029 16.9 0.0 1.4 1 0 0 1 1 1 1 Sugar-transfer associated ATP-grasp Dala_Dala_lig_C PF07478.13 OAP58789.1 - 0.047 13.2 0.0 0.095 12.2 0.0 1.4 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus DUF2118 PF09891.9 OAP58789.1 - 0.051 13.5 0.9 0.092 12.7 0.1 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2118) NQRA PF05896.11 OAP58789.1 - 0.067 12.6 0.2 6.4 6.1 0.0 2.2 1 1 1 2 2 2 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) Peptidase_M76 PF09768.9 OAP58790.1 - 1.3e-60 204.1 5.8 7.6e-58 195.1 5.8 2.0 1 1 0 1 1 1 1 Peptidase M76 family SprT-like PF10263.9 OAP58790.1 - 0.0013 18.6 0.4 0.0029 17.4 0.2 1.6 1 1 0 1 1 1 1 SprT-like family Peptidase_M91 PF14891.6 OAP58790.1 - 0.013 15.8 0.1 0.018 15.4 0.1 1.2 1 0 0 1 1 1 0 Effector protein BSP PF04450.12 OAP58790.1 - 0.064 13.0 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Peptidase of plants and bacteria DA1-like PF12315.8 OAP58790.1 - 0.3 10.4 0.0 0.3 10.4 0.0 1.6 2 0 0 2 2 2 0 Protein DA1 KRE9 PF05390.11 OAP58791.1 - 5.2e-14 52.8 8.5 5.2e-14 52.8 8.5 2.2 2 0 0 2 2 2 1 Yeast cell wall synthesis protein KRE9/KNH1 GPI-anchored PF10342.9 OAP58791.1 - 1e-11 45.4 0.7 1.9e-11 44.5 0.1 1.8 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family BACON PF13004.7 OAP58791.1 - 1.6 8.8 5.2 0.63 10.1 0.3 2.5 2 1 0 2 2 2 0 Putative binding domain, N-terminal SRPRB PF09439.10 OAP58792.1 - 6.5e-22 77.8 0.0 3.1e-20 72.4 0.0 2.1 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 OAP58792.1 - 3.4e-05 23.9 0.0 8.3e-05 22.7 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 OAP58792.1 - 5e-05 22.8 0.0 0.0051 16.3 0.0 2.4 2 1 0 2 2 2 1 ADP-ribosylation factor family AAA_16 PF13191.6 OAP58792.1 - 0.00031 21.2 0.2 0.00052 20.4 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain ATP_bind_1 PF03029.17 OAP58792.1 - 0.00039 20.3 0.0 0.16 11.7 0.0 2.3 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 OAP58792.1 - 0.00068 19.6 0.4 0.019 14.9 0.1 2.6 3 0 0 3 3 3 1 RsgA GTPase ABC_tran PF00005.27 OAP58792.1 - 0.0033 18.0 0.1 0.0058 17.1 0.1 1.3 1 1 0 1 1 1 1 ABC transporter GTP_EFTU PF00009.27 OAP58792.1 - 0.0038 16.8 0.0 0.031 13.8 0.0 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain TniB PF05621.11 OAP58792.1 - 0.0049 16.3 0.0 0.0094 15.4 0.0 1.4 1 0 0 1 1 1 1 Bacterial TniB protein AAA_18 PF13238.6 OAP58792.1 - 0.0078 16.8 0.1 0.019 15.5 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 OAP58792.1 - 0.012 16.0 0.2 0.051 14.0 0.2 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Roc PF08477.13 OAP58792.1 - 0.019 15.2 0.0 0.096 12.9 0.0 2.0 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 OAP58792.1 - 0.04 13.1 0.0 2.3 7.3 0.0 2.0 1 1 1 2 2 2 0 G-protein alpha subunit AAA_5 PF07728.14 OAP58792.1 - 0.052 13.6 0.0 0.095 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Gtr1_RagA PF04670.12 OAP58792.1 - 0.053 12.9 0.0 0.14 11.5 0.0 1.7 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_29 PF13555.6 OAP58792.1 - 0.057 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.6 OAP58792.1 - 0.074 12.8 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain BatA PF07584.11 OAP58792.1 - 0.082 13.3 0.7 0.14 12.6 0.2 1.7 2 0 0 2 2 1 0 Aerotolerance regulator N-terminal AAA_28 PF13521.6 OAP58792.1 - 0.11 12.8 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 OAP58792.1 - 0.13 12.0 0.0 0.48 10.2 0.0 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 OAP58792.1 - 0.13 12.5 0.0 0.2 11.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain RuvB_N PF05496.12 OAP58792.1 - 0.13 12.0 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain cobW PF02492.19 OAP58792.1 - 0.17 11.5 0.0 1.9 8.0 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Acetyltransf_1 PF00583.25 OAP58793.1 - 6.5e-19 68.3 0.0 9.4e-19 67.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 OAP58793.1 - 5.6e-11 42.3 0.1 1.7e-10 40.7 0.0 1.7 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_10 PF13673.7 OAP58793.1 - 8.1e-10 38.7 0.0 1.2e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OAP58793.1 - 4.5e-09 36.6 0.0 7.1e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 OAP58793.1 - 8.9e-08 32.9 0.0 1.1e-07 32.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 OAP58793.1 - 3.1e-06 26.9 0.0 5.1e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 OAP58793.1 - 0.01 15.9 0.1 0.028 14.5 0.0 1.8 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 OAP58793.1 - 0.011 15.9 0.0 0.019 15.1 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 OAP58793.1 - 0.05 13.2 0.0 0.074 12.6 0.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase Acetyltransf_18 PF18014.1 OAP58793.1 - 0.08 12.8 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain LCAT PF02450.15 OAP58794.1 - 6.2e-104 348.3 0.1 8.1e-104 347.9 0.1 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Lipase_2 PF01674.18 OAP58794.1 - 2.8e-05 23.8 0.0 5.5e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 2) DUF1749 PF08538.10 OAP58794.1 - 0.021 13.9 0.0 0.034 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) DUF900 PF05990.12 OAP58794.1 - 0.077 12.5 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) PAP2_3 PF14378.6 OAP58795.1 - 2.9e-24 85.8 15.7 5.9e-24 84.8 15.7 1.5 1 0 0 1 1 1 1 PAP2 superfamily PAP2 PF01569.21 OAP58795.1 - 1.3e-09 38.0 7.6 1.3e-09 38.0 7.6 2.2 2 0 0 2 2 2 1 PAP2 superfamily FMN_dh PF01070.18 OAP58796.1 - 1.8e-118 395.5 0.0 2.1e-118 395.3 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 OAP58796.1 - 6e-11 41.9 0.4 3.9e-08 32.7 0.1 2.5 3 0 0 3 3 3 2 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 OAP58796.1 - 4.6e-05 22.7 0.0 0.00011 21.4 0.1 1.6 2 0 0 2 2 2 1 Conserved region in glutamate synthase NMO PF03060.15 OAP58796.1 - 6.3e-05 22.5 0.3 0.00012 21.6 0.3 1.4 1 0 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.21 OAP58796.1 - 0.0038 16.7 0.1 0.044 13.2 0.0 2.5 1 1 1 2 2 2 1 Histidine biosynthesis protein ThiG PF05690.14 OAP58796.1 - 0.043 13.1 0.2 1.4 8.1 0.1 2.5 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG CDT1_C PF16679.5 OAP58797.1 - 2.8e-12 46.9 0.0 6.3e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 DNA replication factor Cdt1 C-terminal domain DTHCT PF08070.11 OAP58797.1 - 0.047 14.4 1.7 0.058 14.1 0.4 1.9 2 0 0 2 2 2 0 DTHCT (NUC029) region Pex24p PF06398.11 OAP58798.1 - 1.6e-08 34.0 8.9 2.7e-08 33.2 8.9 1.4 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Apolipoprotein PF01442.18 OAP58799.1 - 2e-05 24.6 7.0 2.5e-05 24.3 7.0 1.0 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain V-ATPase_G_2 PF16999.5 OAP58799.1 - 0.011 16.1 13.1 0.017 15.5 13.1 1.4 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit DUF809 PF05663.11 OAP58799.1 - 1 9.5 3.4 1.4 9.0 3.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF809) OmpH PF03938.14 OAP58799.1 - 1.2 9.5 12.4 1.8 8.9 12.4 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) ISG65-75 PF11727.8 OAP58799.1 - 2.3 7.4 13.2 3 7.0 13.2 1.2 1 0 0 1 1 1 0 Invariant surface glycoprotein DUF4200 PF13863.6 OAP58799.1 - 2.7 8.4 12.4 6.1 7.3 12.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) BAR PF03114.18 OAP58799.1 - 5 6.7 10.4 7.6 6.1 6.1 2.0 1 1 1 2 2 2 0 BAR domain DUF4407 PF14362.6 OAP58799.1 - 6.2 6.1 10.1 8.3 5.7 10.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF883 PF05957.13 OAP58799.1 - 6.2 7.5 15.3 0.081 13.5 7.1 2.1 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Helicase_C_2 PF13307.6 OAP58800.1 - 1.9e-54 184.4 0.0 6e-54 182.8 0.0 1.9 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 OAP58800.1 - 2.1e-47 161.0 0.0 5.1e-47 159.8 0.0 1.7 1 0 0 1 1 1 1 DEAD_2 ResIII PF04851.15 OAP58800.1 - 0.0027 17.7 0.3 3.7 7.5 0.0 2.8 2 1 0 2 2 2 2 Type III restriction enzyme, res subunit HBB PF06777.11 OAP58800.1 - 0.0054 16.4 0.0 0.019 14.7 0.0 1.9 2 0 0 2 2 2 1 Helical and beta-bridge domain PhoH PF02562.16 OAP58800.1 - 0.0071 15.8 0.0 2.1 7.7 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein DEAD PF00270.29 OAP58800.1 - 0.028 14.2 0.1 4.6 7.0 0.0 2.6 2 1 0 2 2 2 0 DEAD/DEAH box helicase Brix PF04427.18 OAP58800.1 - 0.064 13.4 0.0 0.13 12.3 0.0 1.7 1 1 0 1 1 1 0 Brix domain AAA_22 PF13401.6 OAP58800.1 - 0.091 13.0 1.4 3.9 7.8 0.0 2.8 2 1 0 2 2 2 0 AAA domain Sel1 PF08238.12 OAP58801.1 - 1.2e-21 76.6 18.7 1.2e-07 32.1 0.1 6.7 7 0 0 7 7 7 5 Sel1 repeat RTA1 PF04479.13 OAP58802.1 - 0.2 11.3 12.3 0.16 11.5 7.2 2.4 1 1 0 2 2 2 0 RTA1 like protein zf-C2H2_assoc PF16606.5 OAP58802.1 - 0.33 11.2 1.7 1 9.6 0.2 2.3 2 0 0 2 2 2 0 Unstructured conserved, between two C2H2-type zinc-fingers DUF2393 PF09624.10 OAP58802.1 - 3.5 7.6 5.4 1.9 8.5 0.4 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2393) DUF4131 PF13567.6 OAP58802.1 - 3.9 7.1 0.0 3.9 7.1 0.0 3.7 1 1 3 4 4 4 0 Domain of unknown function (DUF4131) DUF5373 PF17343.2 OAP58802.1 - 5.7 6.7 11.9 1.1 9.0 8.0 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5373) Mpv17_PMP22 PF04117.12 OAP58803.1 - 1.9e-16 60.0 8.8 3.8e-16 59.1 8.8 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family zf-RING_2 PF13639.6 OAP58804.1 - 3e-10 40.2 5.2 4.6e-10 39.7 5.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 OAP58804.1 - 3e-08 33.4 1.8 4.2e-08 32.9 1.8 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAP58804.1 - 3.7e-07 29.9 3.4 5.7e-07 29.3 3.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OAP58804.1 - 4.8e-07 29.5 5.7 7.4e-07 28.9 5.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OAP58804.1 - 1.4e-06 28.5 4.0 3.9e-06 27.1 4.0 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 OAP58804.1 - 0.0032 17.2 2.2 0.006 16.3 2.2 1.5 1 0 0 1 1 1 1 RING-like zinc finger Prok-RING_4 PF14447.6 OAP58804.1 - 0.034 14.0 3.4 0.055 13.3 3.4 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 OAP58804.1 - 0.044 13.7 2.5 0.081 12.9 2.5 1.5 1 0 0 1 1 1 0 zinc-RING finger domain ADH_N_2 PF16884.5 OAP58805.1 - 7.3e-13 48.4 0.0 1.8e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 OAP58805.1 - 1.6e-11 44.3 0.0 2.3e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAP58805.1 - 1.4e-08 35.8 0.0 2.7e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Peptidase_M16 PF00675.20 OAP58806.1 - 3.9e-38 130.8 1.3 2e-20 73.3 0.0 3.4 3 1 1 4 4 4 2 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 OAP58806.1 - 4.1e-37 128.0 0.0 7.2e-37 127.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase M16 inactive domain Zn_clus PF00172.18 OAP58807.1 - 3.2e-08 33.6 8.9 5.3e-08 32.8 8.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ACOX PF01756.19 OAP58807.1 - 0.052 13.1 0.0 0.23 11.0 0.0 2.1 1 1 1 2 2 2 0 Acyl-CoA oxidase DUF5106 PF17127.4 OAP58807.1 - 0.17 12.2 0.1 0.8 10.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5106) FMO-like PF00743.19 OAP58808.1 - 2.3e-19 69.3 0.8 1.8e-14 53.1 0.1 3.2 2 2 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OAP58808.1 - 2.5e-12 46.8 0.0 6.2e-12 45.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 OAP58808.1 - 3.7e-10 39.5 0.0 1.5e-07 30.9 0.0 3.2 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 OAP58808.1 - 8.3e-08 31.8 0.0 7.4e-07 28.7 0.0 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAP58808.1 - 3e-06 26.7 0.0 0.0003 20.1 0.0 2.7 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAP58808.1 - 0.014 14.6 0.0 0.046 13.0 0.0 1.8 2 0 0 2 2 2 0 Thi4 family DAO PF01266.24 OAP58808.1 - 0.026 14.1 0.9 0.36 10.3 0.9 2.5 1 1 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 OAP58808.1 - 0.028 14.4 3.1 0.35 10.8 0.0 3.0 3 0 0 3 3 3 0 FAD-NAD(P)-binding DUF2204 PF09970.9 OAP58808.1 - 0.15 11.7 0.0 0.31 10.6 0.0 1.5 1 0 0 1 1 1 0 Nucleotidyl transferase of unknown function (DUF2204) Pyr_redox PF00070.27 OAP58808.1 - 0.26 11.9 1.4 2.2 8.9 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase CybS PF05328.12 OAP58809.1 - 2e-48 163.5 0.0 2.5e-48 163.1 0.0 1.1 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit Sdh_cyt PF01127.22 OAP58809.1 - 0.0064 16.5 5.2 0.028 14.5 1.5 2.1 1 1 1 2 2 2 2 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Maf PF02545.14 OAP58810.1 - 7.1e-52 175.6 0.1 8.4e-52 175.4 0.1 1.0 1 0 0 1 1 1 1 Maf-like protein Rubis-subs-bind PF09273.11 OAP58810.1 - 0.048 14.3 0.1 0.23 12.1 0.0 1.9 2 0 0 2 2 2 0 Rubisco LSMT substrate-binding AlaDh_PNT_N PF05222.15 OAP58811.1 - 9.6e-31 106.9 0.0 1.4e-30 106.3 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.21 OAP58811.1 - 2.3e-05 23.8 0.0 7.7e-05 22.1 0.0 1.7 2 1 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain GFA PF04828.14 OAP58812.1 - 0.097 13.0 0.0 0.21 12.0 0.0 1.6 1 0 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme zinc_ribbon_2 PF13240.6 OAP58812.1 - 0.18 11.6 0.5 0.18 11.6 0.5 1.8 2 0 0 2 2 2 0 zinc-ribbon domain HLH PF00010.26 OAP58813.1 - 0.00013 21.8 0.3 0.00053 19.9 0.0 2.0 1 1 1 2 2 2 1 Helix-loop-helix DNA-binding domain Ribonuc_L-PSP PF01042.21 OAP58816.1 - 1.4e-34 118.7 0.0 1.7e-34 118.4 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP DUF1682 PF07946.14 OAP58817.1 - 0.079 12.2 5.2 0.1 11.8 5.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) FUSC PF04632.12 OAP58817.1 - 0.64 8.5 5.8 0.73 8.3 5.8 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family MFS_1 PF07690.16 OAP58819.1 - 4.1e-34 118.1 27.4 4.1e-34 118.1 27.4 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAP58819.1 - 9.4e-10 37.9 11.1 9.4e-10 37.9 11.1 2.5 3 1 0 3 3 3 1 Sugar (and other) transporter DUF3522 PF12036.8 OAP58819.1 - 0.024 14.9 0.8 0.024 14.9 0.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3522) DIOX_N PF14226.6 OAP58820.1 - 3.9e-18 66.3 0.1 1.9e-09 38.3 0.0 2.4 1 1 1 2 2 2 2 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OAP58820.1 - 2.5e-17 63.2 0.0 4.8e-17 62.3 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Sugar_tr PF00083.24 OAP58821.1 - 4.4e-94 315.9 21.5 5.3e-94 315.6 21.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP58821.1 - 1.1e-27 96.9 22.4 1.1e-27 96.9 22.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Pam17 PF08566.10 OAP58821.1 - 0.014 15.2 3.1 0.053 13.4 0.3 2.3 2 0 0 2 2 2 0 Mitochondrial import protein Pam17 RTX PF02382.15 OAP58821.1 - 0.31 10.7 1.7 0.62 9.7 0.9 1.7 2 0 0 2 2 2 0 N-terminal domain in RTX protein Preseq_ALAS PF09029.10 OAP58822.1 - 0.031 14.8 0.8 0.031 14.8 0.8 2.3 1 1 1 2 2 2 0 5-aminolevulinate synthase presequence HAD_2 PF13419.6 OAP58823.1 - 6e-05 23.2 0.0 0.00011 22.3 0.0 1.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase DUF2608 PF11019.8 OAP58823.1 - 0.0038 16.8 0.1 0.0066 16.0 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2608) Hydrolase_like PF13242.6 OAP58823.1 - 0.021 14.9 0.0 0.051 13.6 0.0 1.6 1 0 0 1 1 1 0 HAD-hyrolase-like PilJ PF13675.6 OAP58824.1 - 0.064 13.3 0.5 0.11 12.5 0.5 1.3 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term FAD_binding_4 PF01565.23 OAP58825.1 - 3.6e-20 72.1 1.2 8.7e-20 70.9 1.2 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 OAP58825.1 - 0.00013 21.9 0.0 0.00042 20.3 0.1 1.9 2 0 0 2 2 2 1 Berberine and berberine like Lactamase_B PF00753.27 OAP58826.1 - 4.4e-18 66.0 1.5 6.5e-18 65.5 1.5 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OAP58826.1 - 0.0062 16.1 0.5 0.013 15.0 0.5 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DDE_Tnp_1 PF01609.21 OAP58826.1 - 0.041 13.5 0.1 0.059 13.0 0.1 1.2 1 0 0 1 1 1 0 Transposase DDE domain AMPK1_CBM PF16561.5 OAP58827.1 - 4.5e-05 23.6 0.0 9e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase DUF951 PF06107.11 OAP58827.1 - 0.019 14.8 1.5 0.036 14.0 1.5 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF951) K_channel_TID PF07941.11 OAP58827.1 - 0.093 13.2 1.7 0.18 12.3 1.7 1.5 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain Peptidase_S10 PF00450.22 OAP58828.1 - 4.6e-128 428.2 0.1 5.5e-128 427.9 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Carbpep_Y_N PF05388.11 OAP58828.1 - 4.2e-13 49.9 0.0 1.3e-12 48.4 0.0 1.8 1 0 0 1 1 1 1 Carboxypeptidase Y pro-peptide Euplotes_phero PF05842.11 OAP58828.1 - 0.02 15.5 0.5 0.043 14.4 0.5 1.6 1 1 0 1 1 1 0 Euplotes octocarinatus mating pheromone protein Ribosomal_S13 PF00416.22 OAP58829.1 - 1.3e-54 184.0 2.8 1.5e-54 183.8 2.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 HHH_6 PF14579.6 OAP58829.1 - 0.048 13.9 0.1 0.18 12.1 0.0 1.9 1 1 0 1 1 1 0 Helix-hairpin-helix motif FbpA PF05833.11 OAP58829.1 - 0.05 12.4 0.0 0.053 12.3 0.0 1.2 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) PP28 PF10252.9 OAP58829.1 - 0.093 13.2 0.2 0.22 12.0 0.2 1.6 1 0 0 1 1 1 0 Casein kinase substrate phosphoprotein PP28 2OG-FeII_Oxy PF03171.20 OAP58831.1 - 4.9e-15 55.8 0.0 8.3e-15 55.1 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 OAP58831.1 - 6e-14 52.8 0.0 9.4e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Gpr1_Fun34_YaaH PF01184.19 OAP58832.1 - 1.1e-31 110.1 29.9 3.8e-27 95.3 25.9 2.1 1 1 1 2 2 2 2 GPR1/FUN34/yaaH family FixP_N PF14715.6 OAP58832.1 - 1.8 8.4 0.0 1.8 8.4 0.0 3.5 4 1 0 4 4 4 0 N-terminal domain of cytochrome oxidase-cbb3, FixP Patatin PF01734.22 OAP58833.1 - 1e-16 61.8 0.0 3.7e-16 59.9 0.0 1.9 1 1 0 1 1 1 1 Patatin-like phospholipase LLC1 PF14945.6 OAP58833.1 - 0.088 13.4 0.0 0.16 12.6 0.0 1.5 1 0 0 1 1 1 0 Normal lung function maintenance, Low in Lung Cancer 1 protein Patatin PF01734.22 OAP58834.1 - 2.4e-07 31.2 0.1 6.2e-07 29.8 0.0 1.7 2 0 0 2 2 2 1 Patatin-like phospholipase Pyridoxal_deC PF00282.19 OAP58835.1 - 6.2e-78 262.1 0.0 8.1e-78 261.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Cytochrom_D1 PF02239.16 OAP58837.1 - 1.3e-06 27.2 0.0 0.31 9.5 0.0 3.6 1 1 1 3 3 3 3 Cytochrome D1 heme domain Lactonase PF10282.9 OAP58837.1 - 8.3e-06 25.3 0.0 0.077 12.2 0.0 3.1 2 1 0 2 2 2 2 Lactonase, 7-bladed beta-propeller PQQ_2 PF13360.6 OAP58837.1 - 2.2e-05 24.2 0.0 0.0045 16.6 0.0 2.2 2 0 0 2 2 2 2 PQQ-like domain PQQ_3 PF13570.6 OAP58837.1 - 0.016 15.6 0.6 19 5.9 0.0 4.0 5 0 0 5 5 5 0 PQQ-like domain YfkB PF08756.10 OAP58837.1 - 0.021 14.6 0.0 0.067 13.0 0.0 1.7 2 0 0 2 2 2 0 YfkB-like domain PD40 PF07676.12 OAP58837.1 - 0.071 13.1 0.1 10 6.2 0.0 3.3 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat DnaJ PF00226.31 OAP58838.1 - 7e-19 67.7 0.2 3.2e-18 65.6 0.0 2.1 2 0 0 2 2 2 1 DnaJ domain Cauli_AT PF03233.13 OAP58838.1 - 0.088 12.7 0.5 0.15 11.9 0.5 1.5 1 0 0 1 1 1 0 Aphid transmission protein CP2 PF04516.15 OAP58839.1 - 2e-77 259.6 0.0 3e-77 259.0 0.0 1.2 1 0 0 1 1 1 1 CP2 transcription factor DUF881 PF05949.12 OAP58839.1 - 0.054 13.4 0.1 0.12 12.2 0.1 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF881) Tektin PF03148.14 OAP58839.1 - 0.16 10.6 0.0 0.26 10.0 0.0 1.2 1 0 0 1 1 1 0 Tektin family TMF_DNA_bd PF12329.8 OAP58839.1 - 0.29 11.2 0.9 0.75 9.8 0.9 1.6 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Peptidase_M24 PF00557.24 OAP58840.1 - 8.5e-35 120.3 0.0 1.3e-34 119.7 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF3323 PF11796.8 OAP58840.1 - 0.1 12.5 1.4 0.18 11.7 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function N-terminus (DUF3323) MRJP PF03022.16 OAP58841.1 - 5.2e-22 78.5 0.0 8.6e-22 77.8 0.0 1.3 1 0 0 1 1 1 1 Major royal jelly protein Arylesterase PF01731.20 OAP58841.1 - 0.013 15.7 0.3 1.6 9.0 0.0 2.8 3 0 0 3 3 3 0 Arylesterase Metallopep PF12044.8 OAP58842.1 - 3.1e-165 549.9 0.0 3.9e-165 549.6 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Reprolysin_5 PF13688.6 OAP58842.1 - 0.043 14.0 0.1 0.083 13.0 0.1 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 OAP58842.1 - 0.066 13.1 0.1 0.12 12.2 0.1 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Jacalin PF01419.17 OAP58842.1 - 0.066 13.1 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Jacalin-like lectin domain Reprolysin_3 PF13582.6 OAP58842.1 - 0.2 12.2 0.2 0.35 11.4 0.2 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Whi5 PF08528.11 OAP58843.1 - 1.5e-06 27.7 0.0 2.7e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Whi5 like PDCD2_C PF04194.13 OAP58844.1 - 8.7e-47 159.4 0.0 1e-44 152.7 0.0 2.3 2 0 0 2 2 2 2 Programmed cell death protein 2, C-terminal putative domain DUF4499 PF14934.6 OAP58845.1 - 0.011 16.0 0.5 0.016 15.5 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4499) Glyco_trans_2_3 PF13632.6 OAP58846.1 - 2.2e-52 177.9 2.0 2.2e-52 177.9 2.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 OAP58846.1 - 9.1e-06 25.6 0.0 0.00011 22.1 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 2 Cellulose_synt PF03552.14 OAP58846.1 - 0.0011 17.6 6.1 0.0016 17.0 6.1 1.2 1 0 0 1 1 1 1 Cellulose synthase Glyco_tranf_2_3 PF13641.6 OAP58846.1 - 0.025 14.5 0.0 0.044 13.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 OAP58846.1 - 0.038 13.5 0.1 0.099 12.1 0.0 1.6 2 0 0 2 2 2 0 Glycosyl transferase family 21 Ten1 PF12658.7 OAP58847.1 - 7.8e-30 103.3 0.0 9.5e-30 103.0 0.0 1.0 1 0 0 1 1 1 1 Telomere capping, CST complex subunit Ten1_2 PF15490.6 OAP58847.1 - 0.019 14.7 0.0 0.031 14.0 0.0 1.6 1 1 0 1 1 1 0 Telomere-capping, CST complex subunit Snf7 PF03357.21 OAP58848.1 - 3.4e-35 121.2 21.1 3.4e-35 121.2 21.1 2.0 1 1 1 2 2 2 1 Snf7 DUF3138 PF11336.8 OAP58848.1 - 0.24 10.0 14.2 0.15 10.6 11.5 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3138) Allexi_40kDa PF05549.11 OAP58848.1 - 2.1 7.8 7.3 3.1 7.2 6.6 1.7 1 1 1 2 2 2 0 Allexivirus 40kDa protein PIN_8 PF18476.1 OAP58848.1 - 2.7 7.8 11.9 20 5.0 11.9 2.0 1 1 0 1 1 1 0 PIN like domain DNA_pol_A_exo1 PF01612.20 OAP58849.1 - 5.2e-37 127.3 0.8 8.2e-37 126.6 0.8 1.3 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.12 OAP58849.1 - 1.7e-26 92.7 0.5 1.3e-25 89.9 0.9 2.3 2 0 0 2 2 2 1 PMC2NT (NUC016) domain HRDC PF00570.23 OAP58849.1 - 5e-14 52.0 0.0 1.3e-13 50.7 0.0 1.8 1 0 0 1 1 1 1 HRDC domain Zn_clus PF00172.18 OAP58850.1 - 6.6e-08 32.6 10.9 1.5e-07 31.4 10.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_3 PF01494.19 OAP58851.1 - 5.2e-23 81.8 0.0 9.2e-23 81.0 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 OAP58851.1 - 9.3e-06 25.8 0.0 1.9e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAP58851.1 - 0.00019 20.7 0.1 0.0014 17.9 0.1 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAP58851.1 - 0.0026 17.4 0.1 0.023 14.3 0.0 2.0 1 1 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 OAP58851.1 - 0.011 14.9 0.0 0.22 10.5 0.0 2.5 3 0 0 3 3 3 0 Lycopene cyclase protein SE PF08491.10 OAP58851.1 - 0.011 14.8 0.0 0.063 12.3 0.0 1.9 2 0 0 2 2 2 0 Squalene epoxidase HI0933_like PF03486.14 OAP58851.1 - 0.021 13.5 0.0 0.21 10.3 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.17 OAP58851.1 - 0.024 13.9 0.0 0.036 13.3 0.0 1.2 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 OAP58851.1 - 0.041 13.1 0.0 0.1 11.9 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 OAP58851.1 - 0.089 11.6 0.0 2.2 7.0 0.0 2.5 3 0 0 3 3 3 0 Tryptophan halogenase FMN_red PF03358.15 OAP58852.1 - 4.9e-31 107.6 0.0 6.3e-31 107.2 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 OAP58852.1 - 3.4e-07 30.2 0.0 4.1e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold MFS_1 PF07690.16 OAP58853.1 - 1.3e-35 123.0 24.5 1.3e-35 123.0 24.5 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAP58853.1 - 2.3e-10 40.0 22.6 1.2e-09 37.6 22.5 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 OAP58853.1 - 0.00013 20.6 5.2 0.00019 20.0 5.2 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) PTR2 PF00854.21 OAP58853.1 - 0.0015 17.4 1.2 0.0015 17.4 1.2 2.0 2 0 0 2 2 2 1 POT family Fungal_trans PF04082.18 OAP58854.1 - 1.3e-22 80.1 2.1 1.3e-22 80.1 2.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain FAD_binding_3 PF01494.19 OAP58855.1 - 1.5e-23 83.6 0.0 2.2e-23 83.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain SE PF08491.10 OAP58855.1 - 1.4e-06 27.5 0.0 2.9e-06 26.5 0.0 1.5 1 1 0 1 1 1 1 Squalene epoxidase Trp_halogenase PF04820.14 OAP58855.1 - 6e-06 25.4 2.2 0.013 14.4 0.0 2.3 2 0 0 2 2 2 2 Tryptophan halogenase DAO PF01266.24 OAP58855.1 - 2.7e-05 23.9 3.1 0.045 13.3 3.7 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 OAP58855.1 - 6e-05 23.1 1.4 0.032 14.2 0.2 2.8 3 0 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 OAP58855.1 - 0.00024 20.4 0.6 0.18 11.0 0.7 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAP58855.1 - 0.00032 20.8 1.8 0.00043 20.5 0.2 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 OAP58855.1 - 0.0064 15.8 0.1 0.015 14.6 0.0 1.6 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 OAP58855.1 - 0.058 12.5 0.2 0.099 11.7 0.2 1.4 1 0 0 1 1 1 0 FAD binding domain MCRA PF06100.11 OAP58855.1 - 0.083 11.7 2.6 0.062 12.1 0.9 1.5 2 0 0 2 2 2 0 MCRA family HI0933_like PF03486.14 OAP58855.1 - 0.098 11.3 0.1 0.16 10.6 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein Amidohydro_2 PF04909.14 OAP58856.1 - 2.1e-26 93.4 0.1 2.8e-26 93.0 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase UPF0203 PF05254.12 OAP58857.1 - 1.8e-27 95.4 1.8 2.1e-27 95.2 1.8 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) COX17 PF05051.13 OAP58857.1 - 2.5e-05 24.5 0.8 5e-05 23.6 0.8 1.5 1 1 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.10 OAP58857.1 - 0.00097 19.1 2.2 0.05 13.6 0.1 2.1 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like UCR_hinge PF02320.16 OAP58857.1 - 0.016 15.4 3.5 1.9 8.7 0.1 2.1 1 1 1 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein DUF5339 PF17274.2 OAP58857.1 - 0.092 13.6 1.5 0.45 11.4 0.1 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5339) 2OG-FeII_Oxy_3 PF13640.6 OAP58858.1 - 3.3e-10 40.7 0.0 5.5e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 OAP58858.1 - 0.091 13.3 0.0 0.17 12.4 0.0 1.4 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Forkhead PF00250.18 OAP58859.1 - 6.8e-15 55.1 0.0 1.3e-14 54.2 0.0 1.5 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 OAP58859.1 - 2e-06 28.0 0.1 4.6e-06 26.9 0.1 1.6 1 0 0 1 1 1 1 FHA domain FHA_2 PF17913.1 OAP58859.1 - 0.0023 18.1 0.0 0.0045 17.2 0.0 1.4 1 0 0 1 1 1 1 FHA domain Prenylcys_lyase PF07156.14 OAP58860.1 - 2.2e-78 263.9 0.0 5.4e-78 262.6 0.0 1.5 1 1 0 1 1 1 1 Prenylcysteine lyase Amino_oxidase PF01593.24 OAP58860.1 - 1.2e-11 44.6 0.0 4.5e-11 42.7 0.0 1.8 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OAP58860.1 - 1.9e-09 37.6 0.0 3.7e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 OAP58860.1 - 0.00041 20.4 0.0 0.0014 18.7 0.0 1.8 2 0 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.24 OAP58860.1 - 0.0013 18.4 0.0 0.044 13.4 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAP58860.1 - 0.06 12.6 0.0 0.76 8.9 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Nuc_deoxyrib_tr PF05014.15 OAP58861.1 - 6.3e-10 39.2 0.0 1.2e-09 38.3 0.0 1.5 1 0 0 1 1 1 1 Nucleoside 2-deoxyribosyltransferase adh_short_C2 PF13561.6 OAP58862.1 - 4.4e-26 91.9 0.0 5.6e-26 91.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP58862.1 - 7.4e-19 68.0 0.0 1.1e-18 67.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAP58862.1 - 4.4e-07 30.0 0.0 6.6e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OAP58862.1 - 0.097 11.8 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein ADH_N PF08240.12 OAP58864.1 - 5.4e-28 97.1 0.4 8.8e-28 96.4 0.4 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAP58864.1 - 3.8e-22 78.7 0.1 6.1e-22 78.0 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAP58864.1 - 9.8e-06 26.7 0.1 1.6e-05 26.0 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 OAP58864.1 - 0.0018 17.6 0.2 0.0034 16.7 0.2 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Aldedh PF00171.22 OAP58865.1 - 6.9e-128 427.0 0.9 7.8e-128 426.9 0.9 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Peptidase_M24 PF00557.24 OAP58866.1 - 8.1e-53 179.2 0.1 1.1e-52 178.8 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 OAP58866.1 - 1.9e-24 85.7 0.0 3.4e-24 84.9 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Glyco_hydro_76 PF03663.14 OAP58867.1 - 8.1e-24 84.8 8.6 1.1e-23 84.4 8.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 adh_short PF00106.25 OAP58868.1 - 2e-35 122.0 0.0 2.8e-35 121.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP58868.1 - 4.8e-18 65.6 0.0 5.6e-18 65.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP58868.1 - 2.7e-07 30.7 0.0 4.7e-07 29.9 0.0 1.4 1 1 0 1 1 1 1 KR domain F420_oxidored PF03807.17 OAP58868.1 - 7.8e-05 23.2 0.0 0.00018 22.0 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 OAP58868.1 - 0.00042 20.4 0.0 0.00077 19.5 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NmrA PF05368.13 OAP58868.1 - 0.00044 19.9 0.1 0.0024 17.4 0.0 1.9 2 0 0 2 2 2 1 NmrA-like family Epimerase PF01370.21 OAP58868.1 - 0.0012 18.4 0.0 0.0045 16.5 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.19 OAP58868.1 - 0.0091 15.4 0.0 0.016 14.6 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 OAP58868.1 - 0.016 15.5 0.0 0.029 14.7 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain FTR PF01913.18 OAP58868.1 - 0.028 14.4 0.0 0.048 13.6 0.0 1.3 1 0 0 1 1 1 0 Formylmethanofuran-tetrahydromethanopterin formyltransferase NAD_binding_10 PF13460.6 OAP58868.1 - 0.035 14.0 0.0 0.051 13.5 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding ApbA PF02558.16 OAP58868.1 - 0.076 12.7 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Polysacc_synt_2 PF02719.15 OAP58868.1 - 0.085 12.0 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Pyr_redox PF00070.27 OAP58868.1 - 0.13 12.8 0.1 0.41 11.2 0.0 1.9 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 OAP58868.1 - 0.16 12.2 0.0 0.4 11.0 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain GDP_Man_Dehyd PF16363.5 OAP58868.1 - 0.16 11.3 0.0 0.42 10.0 0.0 1.7 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase TRI12 PF06609.13 OAP58869.1 - 1.4e-25 89.8 17.1 1.7e-25 89.5 17.1 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAP58869.1 - 2.7e-23 82.5 43.2 4.3e-21 75.2 42.6 2.7 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAP58869.1 - 2.4e-08 33.3 23.2 1e-07 31.2 3.7 2.8 2 1 1 3 3 3 2 Sugar (and other) transporter YfhO PF09586.10 OAP58869.1 - 0.011 14.1 0.8 0.018 13.3 0.8 1.3 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DUF2085 PF09858.9 OAP58869.1 - 0.018 15.5 1.4 0.018 15.5 1.4 3.7 3 1 1 4 4 4 0 Predicted membrane protein (DUF2085) Peptidase_S15 PF02129.18 OAP58870.1 - 4.7e-35 121.5 0.6 3.2e-33 115.5 0.2 2.1 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 OAP58870.1 - 8.4e-24 84.8 0.0 1.3e-23 84.1 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Fungal_trans PF04082.18 OAP58871.1 - 7.2e-16 58.0 0.1 1.4e-15 57.0 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain ResB PF05140.14 OAP58871.1 - 0.1 11.3 0.3 0.18 10.5 0.3 1.3 1 0 0 1 1 1 0 ResB-like family HgmA PF04209.13 OAP58872.1 - 3.3e-187 622.4 0.1 3.8e-187 622.2 0.1 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase FAA_hydrolase PF01557.18 OAP58873.1 - 9e-52 175.9 0.0 1.2e-51 175.4 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 OAP58873.1 - 8.9e-30 103.0 0.0 2.2e-29 101.8 0.0 1.7 2 0 0 2 2 2 1 Fumarylacetoacetase N-terminal p450 PF00067.22 OAP58874.1 - 1.4e-58 198.8 0.0 1.6e-58 198.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Abhydrolase_6 PF12697.7 OAP58875.1 - 1e-12 49.1 2.5 1.2e-12 48.9 2.5 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAP58875.1 - 1.3e-05 24.6 0.0 8.2e-05 22.0 0.0 2.2 1 1 0 1 1 1 1 Serine aminopeptidase, S33 FliG_M PF14841.6 OAP58875.1 - 0.078 13.2 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 FliG middle domain PGAP1 PF07819.13 OAP58875.1 - 0.08 12.6 0.1 0.36 10.5 0.0 2.0 3 0 0 3 3 3 0 PGAP1-like protein SLATT_fungal PF18142.1 OAP58876.1 - 1.4e-36 125.1 0.8 2.6e-36 124.2 0.8 1.4 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain SUIM_assoc PF16619.5 OAP58876.1 - 0.015 15.3 9.2 0.034 14.2 9.2 1.6 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 SAPS PF04499.15 OAP58876.1 - 0.26 10.0 3.3 0.3 9.8 3.3 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein BTB PF00651.31 OAP58877.1 - 8.1e-08 32.5 0.0 1.6e-07 31.5 0.0 1.5 1 1 0 1 1 1 1 BTB/POZ domain BSP_II PF05432.11 OAP58877.1 - 0.011 15.5 11.4 0.019 14.6 11.4 1.4 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Vfa1 PF08432.10 OAP58877.1 - 0.021 15.2 5.8 0.032 14.5 5.8 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CENP-B_dimeris PF09026.10 OAP58877.1 - 0.035 14.5 15.8 0.09 13.2 15.8 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain BUD22 PF09073.10 OAP58877.1 - 0.27 10.6 13.2 0.4 10.0 13.2 1.2 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 OAP58877.1 - 0.31 9.2 15.0 0.42 8.8 15.0 1.1 1 0 0 1 1 1 0 Nop14-like family DUF4611 PF15387.6 OAP58877.1 - 0.49 10.6 11.8 1.3 9.3 11.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) RNA_pol_3_Rpc31 PF11705.8 OAP58877.1 - 0.54 10.5 22.2 1 9.6 22.2 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Myc_N PF01056.18 OAP58877.1 - 0.59 10.0 6.6 1.3 8.8 6.6 1.6 1 0 0 1 1 1 0 Myc amino-terminal region RXT2_N PF08595.11 OAP58877.1 - 0.83 9.7 9.1 1.5 8.9 9.1 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal FAM176 PF14851.6 OAP58877.1 - 0.89 9.2 8.9 1.7 8.3 8.9 1.4 1 0 0 1 1 1 0 FAM176 family Cwf_Cwc_15 PF04889.12 OAP58877.1 - 2.1 8.0 18.1 3.4 7.3 18.1 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF2722 PF10846.8 OAP58877.1 - 2.6 6.9 8.1 4.1 6.3 8.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) NPR3 PF03666.13 OAP58877.1 - 2.7 6.7 6.3 3.9 6.2 6.3 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF2457 PF10446.9 OAP58877.1 - 3.1 6.9 21.4 5.3 6.1 21.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) PI3K_1B_p101 PF10486.9 OAP58877.1 - 3.1 5.4 4.6 4.6 4.9 4.6 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Pox_Ag35 PF03286.14 OAP58877.1 - 3.8 7.3 12.7 6.8 6.4 12.7 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein FYDLN_acid PF09538.10 OAP58877.1 - 3.8 8.2 15.5 8.3 7.1 15.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) NOA36 PF06524.12 OAP58877.1 - 4.1 6.7 18.2 7.4 5.8 18.2 1.4 1 0 0 1 1 1 0 NOA36 protein Med17 PF10156.9 OAP58877.1 - 4.1 6.0 6.9 5.9 5.5 6.9 1.1 1 0 0 1 1 1 0 Subunit 17 of Mediator complex TRAP_alpha PF03896.16 OAP58877.1 - 4.3 6.5 7.5 6.3 5.9 7.5 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Astro_capsid_p PF12226.8 OAP58877.1 - 4.6 6.3 16.9 7.3 5.6 16.9 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein DUF4746 PF15928.5 OAP58877.1 - 5.1 6.4 10.3 7.7 5.8 10.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) CDC45 PF02724.14 OAP58877.1 - 8.6 4.5 13.5 12 4.0 13.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Mto2_bdg PF12808.7 OAP58878.1 - 2.8e-20 72.4 31.5 1.5e-17 63.6 19.2 11.4 12 1 0 12 12 12 2 Micro-tubular organiser Mto1 C-term Mto2-binding region Cnn_1N PF07989.11 OAP58878.1 - 2.8e-19 69.0 10.4 2.8e-19 69.0 10.4 12.2 10 3 3 13 13 13 2 Centrosomin N-terminal motif 1 Cep57_MT_bd PF06657.13 OAP58878.1 - 0.0023 18.4 1.5 0.0023 18.4 1.5 10.1 9 3 3 13 13 13 1 Centrosome microtubule-binding domain of Cep57 NFACT-R_1 PF05670.13 OAP58878.1 - 0.094 13.4 0.0 0.36 11.5 0.0 2.0 1 0 0 1 1 1 0 NFACT protein RNA binding domain DUF1664 PF07889.12 OAP58878.1 - 0.13 12.3 0.1 0.13 12.3 0.1 8.8 5 1 4 10 10 9 0 Protein of unknown function (DUF1664) MHC_II_beta PF00969.19 OAP58878.1 - 0.14 12.3 2.1 0.41 10.8 1.1 2.4 2 0 0 2 2 2 0 Class II histocompatibility antigen, beta domain DASH_Duo1 PF08651.10 OAP58878.1 - 0.88 9.4 13.8 1.3 8.9 0.1 5.2 5 1 2 7 7 7 0 DASH complex subunit Duo1 Sec8_exocyst PF04048.14 OAP58878.1 - 2.1 8.3 23.1 0.13 12.1 0.5 6.0 5 2 2 7 7 7 0 Sec8 exocyst complex component specific domain Sec7 PF01369.20 OAP58879.1 - 4.2e-31 108.1 0.0 8.1e-31 107.1 0.0 1.4 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.6 OAP58879.1 - 2.4e-17 63.4 0.0 1.2e-16 61.1 0.0 2.4 1 0 0 1 1 1 1 Pleckstrin homology domain UNC-50 PF05216.13 OAP58880.1 - 3.7e-82 275.2 12.4 4.1e-82 275.0 12.4 1.0 1 0 0 1 1 1 1 UNC-50 family Glyco_hydro_44 PF12891.7 OAP58880.1 - 0.068 13.1 0.0 0.097 12.6 0.0 1.1 1 0 0 1 1 1 0 Glycoside hydrolase family 44 GFA PF04828.14 OAP58881.1 - 1e-23 83.5 0.5 1.6e-23 82.9 0.5 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme NOB1_Zn_bind PF08772.11 OAP58881.1 - 0.058 13.6 1.8 2.3 8.5 0.0 2.4 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like Auto_anti-p27 PF06677.12 OAP58881.1 - 0.14 12.4 0.1 0.14 12.4 0.1 2.1 2 1 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Rpr2 PF04032.16 OAP58881.1 - 0.14 12.4 0.9 0.29 11.4 0.1 1.8 1 1 1 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain NTP_transf_2 PF01909.23 OAP58882.1 - 0.0021 18.3 0.0 0.0063 16.8 0.0 1.9 2 0 0 2 2 2 1 Nucleotidyltransferase domain Glyco_transf_20 PF00982.21 OAP58883.1 - 3.7e-153 510.6 0.0 7.4e-153 509.6 0.0 1.4 2 0 0 2 2 2 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 OAP58883.1 - 2.6e-82 275.5 0.0 4.2e-82 274.8 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.12 OAP58883.1 - 0.0016 18.2 0.0 0.19 11.4 0.0 2.3 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase MFS_1 PF07690.16 OAP58884.1 - 7.9e-19 67.8 52.1 7.9e-19 67.8 52.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PP28 PF10252.9 OAP58885.1 - 4.1e-30 104.1 19.1 4.1e-30 104.1 19.1 2.7 3 0 0 3 3 3 2 Casein kinase substrate phosphoprotein PP28 Nop53 PF07767.11 OAP58885.1 - 0.5 9.7 51.9 1.4 8.3 13.2 2.0 1 1 1 2 2 2 0 Nop53 (60S ribosomal biogenesis) DUF1917 PF08939.10 OAP58886.1 - 1.6e-65 221.6 2.5 1.7e-60 205.1 0.2 3.1 2 1 0 2 2 2 2 Domain of unknown function (DUF1917) Granin PF01271.17 OAP58886.1 - 0.043 12.7 5.1 0.062 12.2 5.1 1.1 1 0 0 1 1 1 0 Granin (chromogranin or secretogranin) DUF1455 PF07306.11 OAP58886.1 - 0.9 9.5 4.0 0.41 10.6 1.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1455) HeLo PF14479.6 OAP58887.1 - 1.6e-24 86.9 0.4 3e-24 86.0 0.4 1.4 1 0 0 1 1 1 1 Prion-inhibition and propagation Pkinase PF00069.25 OAP58887.1 - 0.016 14.6 0.0 0.048 13.0 0.0 1.6 1 1 0 1 1 1 0 Protein kinase domain PfkB PF00294.24 OAP58888.1 - 3e-49 168.0 0.9 4.4e-49 167.4 0.9 1.2 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 OAP58888.1 - 0.0022 17.4 0.0 0.0037 16.7 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase DUF951 PF06107.11 OAP58888.1 - 0.19 11.7 0.4 0.51 10.3 0.0 1.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF951) Pkinase PF00069.25 OAP58889.1 - 1.2e-34 119.9 0.0 1.6e-34 119.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP58889.1 - 3.2e-15 56.1 0.0 4.7e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 OAP58889.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Polyketide_cyc PF03364.20 OAP58890.1 - 0.002 18.3 0.1 0.039 14.1 0.0 2.3 2 0 0 2 2 2 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 OAP58890.1 - 0.0056 16.9 0.1 0.014 15.7 0.1 1.6 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Glyco_transf_20 PF00982.21 OAP58891.1 - 5.1e-163 543.1 0.0 5.8e-163 542.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glyco_trans_1_4 PF13692.6 OAP58891.1 - 0.0068 16.8 0.0 0.013 16.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 OAP58891.1 - 0.024 14.2 0.0 0.42 10.1 0.0 2.3 1 1 0 1 1 1 0 Glycosyl transferases group 1 DUF1598 PF07643.11 OAP58891.1 - 0.077 13.2 0.0 0.21 11.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1598) DUF1624 PF07786.12 OAP58891.1 - 0.16 11.5 0.0 0.26 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1624) Pkinase PF00069.25 OAP58892.1 - 5.4e-17 62.0 0.0 1.4e-16 60.7 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP58892.1 - 2.5e-08 33.5 0.0 4e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAP58892.1 - 0.0034 16.2 0.0 0.0055 15.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OAP58892.1 - 0.0076 16.2 0.0 0.019 14.9 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Oxysterol_BP PF01237.18 OAP58893.1 - 3e-121 404.8 0.3 5.9e-121 403.8 0.3 1.5 1 1 0 1 1 1 1 Oxysterol-binding protein PH_8 PF15409.6 OAP58893.1 - 9.2e-38 128.4 0.1 2.2e-37 127.2 0.1 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 OAP58893.1 - 8.7e-07 29.4 2.1 1.8e-06 28.4 0.0 2.7 3 0 0 3 3 3 1 PH domain Ino80_Iec3 PF14612.6 OAP58894.1 - 2.5e-68 231.3 1.1 3.5e-68 230.8 1.1 1.2 1 0 0 1 1 1 1 IEC3 subunit of the Ino80 complex, chromatin re-modelling RRM_1 PF00076.22 OAP58895.1 - 4.2e-20 71.4 0.0 1.1e-11 44.4 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 OAP58895.1 - 0.011 15.7 0.0 0.044 13.8 0.0 1.9 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RE_XcyI PF09571.10 OAP58895.1 - 0.015 14.6 0.1 0.023 13.9 0.1 1.2 1 0 0 1 1 1 0 XcyI restriction endonuclease Btz PF09405.10 OAP58896.1 - 2.7e-20 73.0 3.1 6.9e-20 71.6 3.1 1.7 1 0 0 1 1 1 1 CASC3/Barentsz eIF4AIII binding N_BRCA1_IG PF16158.5 OAP58897.1 - 1.5e-29 102.7 0.0 4.3e-29 101.2 0.0 1.8 1 0 0 1 1 1 1 Ig-like domain from next to BRCA1 gene ZZ PF00569.17 OAP58897.1 - 1.5e-21 76.0 54.7 5.5e-08 32.5 6.6 4.4 4 0 0 4 4 4 4 Zinc finger, ZZ type C1_2 PF03107.16 OAP58897.1 - 4.6 7.6 52.4 0.13 12.6 7.6 4.5 4 0 0 4 4 4 0 C1 domain IFRD PF05004.13 OAP58898.1 - 1.6e-72 244.2 11.3 2.4e-72 243.7 11.3 1.1 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) Adaptin_N PF01602.20 OAP58898.1 - 0.0077 14.8 0.1 0.011 14.3 0.1 1.4 1 0 0 1 1 1 1 Adaptin N terminal region ADP_ribosyl_GH PF03747.14 OAP58898.1 - 0.056 13.2 0.5 0.11 12.2 0.5 1.5 1 1 0 1 1 1 0 ADP-ribosylglycohydrolase DUF4853 PF16145.5 OAP58898.1 - 0.075 13.2 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4853) DUF2321 PF10083.9 OAP58898.1 - 0.12 12.0 1.5 59 3.2 0.3 3.1 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2321) PAP2_3 PF14378.6 OAP58899.1 - 5.5e-24 84.9 26.9 1.1e-23 83.9 21.2 3.0 2 1 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.6 OAP58899.1 - 0.007 16.9 1.3 0.007 16.9 1.3 3.4 4 1 1 5 5 5 1 PAP2 superfamily C-terminal Acetyltransf_2 PF00797.17 OAP58899.1 - 0.08 12.7 0.2 0.12 12.1 0.2 1.2 1 0 0 1 1 1 0 N-acetyltransferase Fungal_trans_2 PF11951.8 OAP58900.1 - 0.00052 18.9 0.1 0.00099 18.0 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF4012 PF13196.6 OAP58900.1 - 0.16 12.4 0.0 0.31 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4012) Gpi1 PF05024.15 OAP58902.1 - 7.6e-75 251.1 8.1 1.4e-74 250.3 8.1 1.4 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) DUF155 PF02582.14 OAP58904.1 - 4.2e-47 160.5 0.0 6.3e-47 159.9 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Clathrin PF00637.20 OAP58905.1 - 2.6e-17 63.0 0.7 4.3e-15 55.8 0.3 2.6 3 0 0 3 3 3 2 Region in Clathrin and VPS WD40_like PF17005.5 OAP58905.1 - 0.0064 15.9 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 WD40-like domain Vps39_1 PF10366.9 OAP58905.1 - 0.096 13.0 0.2 0.28 11.5 0.2 1.7 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 1 zf-RING_5 PF14634.6 OAP58905.1 - 0.15 12.1 5.0 0.036 14.0 1.2 1.8 2 0 0 2 2 2 0 zinc-RING finger domain Tfb2 PF03849.14 OAP58906.1 - 3.8e-118 394.5 0.0 7.7e-118 393.5 0.0 1.5 1 1 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 OAP58906.1 - 3.2e-22 78.7 0.2 8.3e-22 77.4 0.2 1.8 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 OAP58906.1 - 7.2e-06 26.2 0.1 1.7e-05 25.0 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Zn_clus PF00172.18 OAP58907.1 - 2.7e-07 30.6 4.8 4.9e-07 29.8 4.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 4HBT PF03061.22 OAP58908.1 - 5.8e-12 45.8 0.1 8.6e-12 45.3 0.1 1.3 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.6 OAP58908.1 - 0.015 15.5 0.0 0.021 15.0 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4442) Actin PF00022.19 OAP58909.1 - 2e-88 296.8 0.0 2e-87 293.5 0.0 1.9 1 1 0 1 1 1 1 Actin PilM_2 PF11104.8 OAP58909.1 - 0.023 13.7 0.0 2.2 7.2 0.0 2.2 2 0 0 2 2 2 0 Type IV pilus assembly protein PilM; MreB_Mbl PF06723.13 OAP58909.1 - 0.19 10.5 0.0 0.38 9.5 0.0 1.4 1 0 0 1 1 1 0 MreB/Mbl protein PrgH PF09480.10 OAP58909.1 - 0.21 10.9 0.0 0.31 10.3 0.0 1.1 1 0 0 1 1 1 0 Type III secretion system protein PrgH-EprH (PrgH) DUF4404 PF14357.6 OAP58911.1 - 0.072 13.7 0.1 0.072 13.7 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) Cupin_1 PF00190.22 OAP58912.1 - 3.6e-21 75.4 1.4 6e-21 74.6 1.4 1.3 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 OAP58912.1 - 5.5e-06 26.0 0.0 1.7e-05 24.5 0.0 1.8 1 1 1 2 2 2 1 Cupin domain MannoseP_isomer PF01050.18 OAP58912.1 - 0.21 11.4 0.0 0.32 10.9 0.0 1.2 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase ILVD_EDD PF00920.21 OAP58913.1 - 3e-207 689.3 0.9 3.5e-207 689.1 0.9 1.0 1 0 0 1 1 1 1 Dehydratase family Ferritin_2 PF13668.6 OAP58915.1 - 1.2e-37 129.1 0.8 1.2e-37 129.1 0.8 2.2 2 1 0 2 2 2 1 Ferritin-like domain DUF908 PF06012.12 OAP58915.1 - 0.9 8.9 9.1 1.7 8.0 9.1 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Zn_clus PF00172.18 OAP58916.1 - 5.9e-10 39.1 7.5 9.4e-10 38.5 7.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_transf_28 PF03033.20 OAP58917.1 - 6.5e-29 100.8 0.0 1.3e-28 99.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain GRAM PF02893.20 OAP58917.1 - 3.6e-25 88.0 0.4 2e-21 76.0 0.0 2.7 3 0 0 3 3 3 2 GRAM domain PH PF00169.29 OAP58917.1 - 3.6e-14 53.2 0.6 6.4e-12 45.9 0.5 2.5 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 OAP58917.1 - 6.4e-07 29.8 0.7 1.4e-06 28.6 0.7 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 OAP58917.1 - 0.0005 20.3 0.5 0.0017 18.6 0.3 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain PH_3 PF14593.6 OAP58917.1 - 0.00065 19.8 0.0 0.0016 18.5 0.0 1.6 1 0 0 1 1 1 1 PH domain UDPGT PF00201.18 OAP58917.1 - 0.08 11.7 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase TPP_enzyme_N PF02776.18 OAP58918.1 - 4.3e-26 91.6 0.0 6.9e-26 90.9 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 OAP58918.1 - 3e-20 72.4 0.0 7.4e-20 71.1 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 OAP58918.1 - 2.6e-14 53.3 0.0 6.6e-14 52.0 0.0 1.6 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.20 OAP58918.1 - 0.00068 18.7 0.1 0.0011 18.0 0.1 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Pkinase PF00069.25 OAP58919.1 - 2.7e-64 217.1 0.0 3.8e-64 216.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP58919.1 - 6.5e-45 153.4 0.0 1e-44 152.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAP58919.1 - 8.7e-12 44.9 0.0 2.9e-07 30.1 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 OAP58919.1 - 0.0027 16.6 0.0 0.0062 15.4 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OAP58919.1 - 0.0031 16.9 0.0 0.0061 15.9 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OAP58919.1 - 0.046 13.6 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family MBOAT_2 PF13813.6 OAP58921.1 - 2.8e-14 53.2 3.6 2.8e-14 53.2 3.6 2.5 2 1 0 2 2 2 1 Membrane bound O-acyl transferase family DUF2427 PF10348.9 OAP58922.1 - 8e-28 96.3 0.8 8e-28 96.3 0.8 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) Ytp1 PF10355.9 OAP58922.1 - 2.6e-24 85.9 23.6 2.1e-23 82.9 19.6 3.0 2 1 0 2 2 2 1 Protein of unknown function (Ytp1) Lgl_C PF08596.10 OAP58924.1 - 9.6e-118 393.3 0.0 4.1e-117 391.2 0.0 2.0 2 0 0 2 2 2 1 Lethal giant larvae(Lgl) like, C-terminal ANAPC4_WD40 PF12894.7 OAP58924.1 - 1.8e-08 34.6 0.0 2.1 8.7 0.0 6.0 5 2 0 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OAP58924.1 - 3e-06 27.9 0.1 0.08 13.8 0.1 4.1 2 0 0 2 2 2 2 WD domain, G-beta repeat But2 PF09792.9 OAP58925.1 - 2e-13 50.9 0.4 4.6e-13 49.8 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin 3 binding protein But2 C-terminal domain HET PF06985.11 OAP58927.1 - 2.1e-27 96.3 0.7 1e-26 94.1 0.0 2.2 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Nop14 PF04147.12 OAP58927.1 - 7.9e-06 24.4 31.9 1.1e-05 23.9 31.9 1.1 1 0 0 1 1 1 1 Nop14-like family RNA_pol_Rpc4 PF05132.14 OAP58927.1 - 0.0012 19.3 1.2 0.0028 18.1 1.2 1.6 1 0 0 1 1 1 1 RNA polymerase III RPC4 Mpp10 PF04006.12 OAP58927.1 - 0.0023 16.5 30.9 0.0033 15.9 30.9 1.1 1 0 0 1 1 1 1 Mpp10 protein SDA1 PF05285.12 OAP58927.1 - 0.0057 16.1 39.2 0.0092 15.4 39.2 1.2 1 0 0 1 1 1 1 SDA1 CDC45 PF02724.14 OAP58927.1 - 0.0064 14.8 26.1 0.01 14.2 26.1 1.2 1 0 0 1 1 1 1 CDC45-like protein SAPS PF04499.15 OAP58927.1 - 0.053 12.3 12.0 0.075 11.8 12.0 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CobT PF06213.12 OAP58927.1 - 0.072 12.5 34.5 0.12 11.8 34.5 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT dsRBD2 PF17842.1 OAP58927.1 - 0.17 12.1 0.1 0.49 10.6 0.1 1.8 1 0 0 1 1 1 0 Double-stranded RNA binding domain 2 DUF913 PF06025.12 OAP58927.1 - 0.24 10.3 5.0 0.45 9.4 5.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) RR_TM4-6 PF06459.12 OAP58927.1 - 0.3 10.9 9.1 0.55 10.0 9.1 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 OAP58927.1 - 0.61 8.8 6.4 0.91 8.2 6.4 1.1 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 OAP58927.1 - 1.1 8.4 5.0 1.7 7.8 5.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Smg8_Smg9 PF10220.9 OAP58927.1 - 1.5 7.1 4.0 1.1 7.5 2.1 1.7 2 0 0 2 2 2 0 Smg8_Smg9 Tim54 PF11711.8 OAP58927.1 - 3.6 6.3 9.9 6.6 5.4 9.9 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 TFIIA PF03153.13 OAP58927.1 - 4.8 7.1 32.9 8.4 6.3 32.9 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3106 PF11304.8 OAP58928.1 - 0.065 13.7 0.4 0.11 13.0 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3106) Aminotran_1_2 PF00155.21 OAP58929.1 - 6.2e-39 134.2 0.0 8.1e-39 133.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 OAP58929.1 - 0.00034 19.3 0.0 0.00062 18.4 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Glucan_synthase PF02364.15 OAP58930.1 - 0 1397.3 0.0 0 1396.6 0.0 1.3 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 OAP58930.1 - 1.4e-43 148.3 0.4 4.2e-43 146.8 0.4 1.9 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Glyco_hydro_72 PF03198.14 OAP58931.1 - 1.2e-136 455.2 8.2 1.4e-136 454.9 8.2 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 OAP58931.1 - 1.2e-22 80.3 2.0 3.2e-22 79.0 2.0 1.8 1 0 0 1 1 1 1 X8 domain Glyco_hydro_114 PF03537.13 OAP58931.1 - 0.23 10.7 3.2 8.9 5.5 0.0 2.4 1 1 1 2 2 2 0 Glycoside-hydrolase family GH114 Mog1 PF04603.12 OAP58932.1 - 1.3e-26 93.6 0.0 9.3e-26 90.8 0.0 2.1 1 1 0 1 1 1 1 Ran-interacting Mog1 protein SSP160 PF06933.11 OAP58932.1 - 1.4 7.1 11.8 0.59 8.3 8.7 1.7 2 0 0 2 2 2 0 Special lobe-specific silk protein SSP160 SprT-like PF10263.9 OAP58933.1 - 1e-36 125.2 0.1 1.7e-36 124.5 0.1 1.3 1 0 0 1 1 1 1 SprT-like family Zn_ribbon_SprT PF17283.2 OAP58933.1 - 1.3e-06 28.2 2.2 1.3e-06 28.2 2.2 2.6 2 0 0 2 2 2 1 SprT-like zinc ribbon domain SPT6_acidic PF14632.6 OAP58933.1 - 0.27 11.9 16.9 0.058 14.0 5.1 2.8 2 0 0 2 2 2 0 Acidic N-terminal SPT6 p450 PF00067.22 OAP58934.1 - 1.8e-53 181.9 0.0 2.4e-53 181.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 GvpK PF05121.12 OAP58934.1 - 0.036 14.1 1.7 0.17 11.9 0.0 2.4 2 0 0 2 2 2 0 Gas vesicle protein K ARA70 PF12489.8 OAP58934.1 - 0.14 12.3 0.1 0.27 11.4 0.1 1.4 1 0 0 1 1 1 0 Nuclear coactivator 2OG-FeII_Oxy_3 PF13640.6 OAP58935.1 - 1.3e-09 38.9 0.1 3.1e-09 37.6 0.1 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF3876 PF12992.7 OAP58935.1 - 0.032 14.3 0.0 0.16 12.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function, B. Theta Gene description (DUF3876) 2OG-FeII_Oxy PF03171.20 OAP58935.1 - 0.05 14.1 0.0 0.14 12.7 0.0 1.7 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily ArsB PF02040.15 OAP58937.1 - 8.7e-09 35.2 11.2 8.8e-05 22.0 5.6 2.2 2 0 0 2 2 2 2 Arsenical pump membrane protein zf-C2H2 PF00096.26 OAP58938.1 - 4.3e-06 26.9 11.3 0.0032 17.9 1.5 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OAP58938.1 - 0.00029 21.1 4.1 0.00029 21.1 4.1 2.8 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 OAP58938.1 - 0.019 15.7 15.6 0.052 14.4 2.6 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_5 PF13909.6 OAP58938.1 - 0.37 10.6 3.5 2.4 8.0 0.4 2.6 2 0 0 2 2 2 0 C2H2-type zinc-finger domain COG5 PF10392.9 OAP58939.1 - 5.4e-29 101.0 1.4 1.1e-28 100.0 1.4 1.6 1 0 0 1 1 1 1 Golgi transport complex subunit 5 DUF4611 PF15387.6 OAP58939.1 - 0.035 14.3 3.5 0.08 13.2 3.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Phage_holin_7_1 PF16081.5 OAP58939.1 - 1.1 9.4 3.2 2 8.6 0.1 2.6 3 0 0 3 3 3 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family COX6B PF02297.17 OAP58940.1 - 2.3e-23 82.2 3.8 3.1e-23 81.8 3.8 1.2 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Mobilization_B PF17511.2 OAP58940.1 - 0.082 13.3 0.8 0.11 12.8 0.8 1.1 1 0 0 1 1 1 0 Mobilization protein B DAP3 PF10236.9 OAP58940.1 - 0.09 11.9 0.0 0.092 11.9 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 CLU PF13236.6 OAP58940.1 - 0.093 12.5 0.1 0.14 12.0 0.0 1.3 1 1 0 1 1 1 0 Clustered mitochondria SYS1 PF09801.9 OAP58941.1 - 9.5e-52 175.0 7.7 1.1e-51 174.8 7.7 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network VIT1 PF01988.19 OAP58941.1 - 0.33 10.8 5.3 0.21 11.4 3.9 1.4 1 1 0 1 1 1 0 VIT family NAD_binding_10 PF13460.6 OAP58942.1 - 2.6e-09 37.2 0.1 4e-09 36.6 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAP58942.1 - 5.5e-09 35.8 0.4 3.1e-07 30.1 0.4 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OAP58942.1 - 4.2e-05 22.7 0.1 0.00019 20.5 0.1 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 OAP58942.1 - 0.00018 21.2 0.2 0.0011 18.6 0.2 1.9 2 0 0 2 2 2 1 NmrA-like family GDP_Man_Dehyd PF16363.5 OAP58942.1 - 0.0005 19.6 0.1 0.0044 16.5 0.0 2.3 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase Shikimate_DH PF01488.20 OAP58942.1 - 0.0016 18.5 0.0 0.0024 17.9 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 OAP58942.1 - 0.0025 17.5 0.1 0.0041 16.8 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 OAP58942.1 - 0.0035 17.6 0.1 0.0065 16.7 0.1 1.4 1 0 0 1 1 1 1 TrkA-N domain AlaDh_PNT_C PF01262.21 OAP58942.1 - 0.0067 15.7 0.3 0.01 15.2 0.3 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Seipin PF06775.14 OAP58942.1 - 0.04 14.0 0.0 0.068 13.3 0.0 1.3 1 0 0 1 1 1 0 Putative adipose-regulatory protein (Seipin) NAD_binding_2 PF03446.15 OAP58942.1 - 0.062 13.5 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Get5_bdg PF16843.5 OAP58942.1 - 0.063 12.8 0.1 0.12 11.9 0.1 1.4 1 0 0 1 1 1 0 Binding domain to Get4 on Get5, Golgi to ER traffic protein Polysacc_synt_2 PF02719.15 OAP58942.1 - 0.14 11.2 0.1 0.32 10.1 0.1 1.5 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein DnaJ PF00226.31 OAP58943.1 - 4.4e-21 74.8 3.4 6.7e-21 74.2 1.5 2.3 2 0 0 2 2 2 1 DnaJ domain TPR_9 PF13371.6 OAP58943.1 - 4.8e-13 49.0 0.4 0.004 17.3 0.2 4.8 3 2 1 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 OAP58943.1 - 1.1e-11 44.0 5.3 0.001 18.8 0.0 7.1 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_2 PF07719.17 OAP58943.1 - 2.5e-10 39.7 10.4 0.049 13.8 0.0 8.0 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_19 PF14559.6 OAP58943.1 - 2.3e-08 34.4 3.0 0.018 15.5 0.0 4.7 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 OAP58943.1 - 1e-07 32.1 7.2 7.2 7.5 0.0 7.9 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_8 PF13181.6 OAP58943.1 - 1e-07 31.6 1.1 0.22 11.9 0.0 6.2 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 OAP58943.1 - 0.00011 22.5 5.0 3.8 7.9 0.0 5.8 4 2 1 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 OAP58943.1 - 0.00014 22.4 13.5 3.3 8.8 0.0 6.6 5 3 3 8 8 7 2 Tetratricopeptide repeat TPR_11 PF13414.6 OAP58943.1 - 0.00039 20.0 0.4 0.084 12.6 0.3 4.1 4 1 1 5 5 5 1 TPR repeat TPR_17 PF13431.6 OAP58943.1 - 0.00099 19.3 0.5 0.53 10.8 0.1 4.1 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 OAP58943.1 - 0.0039 17.8 22.0 1.4 9.6 0.0 6.0 5 1 1 6 6 6 3 Tetratricopeptide repeat PknG_TPR PF16918.5 OAP58943.1 - 0.011 14.5 0.2 0.12 11.1 0.0 2.5 3 0 0 3 3 3 0 Protein kinase G tetratricopeptide repeat ANAPC3 PF12895.7 OAP58943.1 - 0.018 15.2 7.8 0.89 9.8 0.4 4.5 5 1 1 6 6 5 0 Anaphase-promoting complex, cyclosome, subunit 3 Toprim_3 PF13362.6 OAP58943.1 - 5.5 7.4 7.5 0.89 10.0 1.1 2.9 2 2 1 3 3 3 0 Toprim domain MOZ_SAS PF01853.18 OAP58944.1 - 2.8e-54 183.5 0.0 1.2e-53 181.4 0.0 1.8 1 1 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 OAP58944.1 - 7.3e-12 44.7 3.1 4.3e-06 26.2 0.0 2.5 2 0 0 2 2 2 2 MYST family zinc finger domain Planc_extracel PF07595.12 OAP58944.1 - 0.59 10.0 6.2 1.6 8.7 0.6 2.8 2 0 0 2 2 2 0 Planctomycete extracellular Macoilin PF09726.9 OAP58945.1 - 2.2 6.7 6.4 3 6.3 6.4 1.1 1 0 0 1 1 1 0 Macoilin family Prefoldin PF02996.17 OAP58946.1 - 6.3e-24 84.2 1.3 3.8e-21 75.2 0.1 2.5 2 1 0 2 2 2 2 Prefoldin subunit Sec2p PF06428.11 OAP58946.1 - 0.00066 19.6 0.4 0.18 11.8 0.0 2.3 2 0 0 2 2 2 2 GDP/GTP exchange factor Sec2p Prefoldin_2 PF01920.20 OAP58946.1 - 0.011 15.7 1.7 0.038 13.9 0.0 2.3 2 1 1 3 3 3 0 Prefoldin subunit YscO PF07321.12 OAP58946.1 - 0.047 13.7 0.1 0.047 13.7 0.1 1.9 2 1 0 2 2 2 0 Type III secretion protein YscO Pinin_SDK_N PF04697.13 OAP58946.1 - 0.16 12.6 3.9 11 6.7 0.4 2.4 2 0 0 2 2 2 0 pinin/SDK conserved region RAP1 PF07218.11 OAP58947.1 - 0.23 9.7 4.1 0.34 9.1 4.1 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF4407 PF14362.6 OAP58947.1 - 2.7 7.2 4.6 4.8 6.4 4.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) GAS PF13851.6 OAP58947.1 - 2.9 7.2 15.7 5.6 6.3 15.7 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding ABC_tran_CTD PF16326.5 OAP58947.1 - 3.1 8.1 15.6 1.9 8.8 1.3 3.2 3 0 0 3 3 3 0 ABC transporter C-terminal domain zf-MIZ PF02891.20 OAP58949.1 - 4.1e-11 42.4 0.1 8.2e-11 41.5 0.1 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 OAP58949.1 - 0.022 14.6 0.0 0.052 13.4 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit SAM_2 PF07647.17 OAP58950.1 - 3.4e-12 46.3 0.2 6.6e-12 45.4 0.2 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_9 PF14604.6 OAP58950.1 - 1.2e-10 41.1 0.0 2.1e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 OAP58950.1 - 1.4e-10 40.6 0.0 2.7e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 SH3 domain PH PF00169.29 OAP58950.1 - 4.7e-10 39.9 0.0 2.3e-09 37.7 0.0 2.2 1 1 0 1 1 1 1 PH domain SAM_1 PF00536.30 OAP58950.1 - 0.0014 19.0 0.2 0.0027 18.1 0.2 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_2 PF07653.17 OAP58950.1 - 0.0046 16.6 0.0 0.0097 15.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain PH_11 PF15413.6 OAP58950.1 - 0.0073 16.7 0.0 0.02 15.3 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain Dscam_C PF12355.8 OAP58952.1 - 0.06 14.3 0.7 0.06 14.3 0.7 2.5 2 0 0 2 2 2 0 Down syndrome cell adhesion molecule C terminal Copper-fist PF00649.18 OAP58952.1 - 0.78 9.3 3.0 1.8 8.1 3.0 1.6 1 0 0 1 1 1 0 Copper fist DNA binding domain 14-3-3 PF00244.20 OAP58953.1 - 1.4e-106 355.0 8.8 1.6e-106 354.8 8.8 1.0 1 0 0 1 1 1 1 14-3-3 protein Imm71 PF15602.6 OAP58953.1 - 0.013 15.6 0.2 0.68 10.0 0.0 2.2 1 1 1 2 2 2 0 Immunity protein 71 TerB PF05099.13 OAP58953.1 - 0.044 13.8 0.2 0.044 13.8 0.2 2.0 3 0 0 3 3 3 0 Tellurite resistance protein TerB FapA PF03961.13 OAP58953.1 - 0.066 11.8 2.4 0.089 11.4 2.4 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF4710 PF15828.5 OAP58953.1 - 0.096 12.8 2.3 0.81 9.9 0.0 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4710) TPR_12 PF13424.6 OAP58953.1 - 0.2 11.9 3.4 0.44 10.9 0.8 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Ima1_N PF09779.9 OAP58953.1 - 0.6 11.0 2.1 4.5 8.1 0.1 2.5 2 1 0 2 2 2 0 Ima1 N-terminal domain TPR_19 PF14559.6 OAP58953.1 - 0.73 10.4 0.1 0.73 10.4 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat IATP PF04568.12 OAP58954.1 - 1e-22 80.4 9.0 7.2e-16 58.4 0.4 2.0 2 0 0 2 2 2 2 Mitochondrial ATPase inhibitor, IATP PKHD_C PF18331.1 OAP58954.1 - 0.0048 16.9 0.2 0.018 15.1 0.3 1.9 2 0 0 2 2 2 1 PKHD-type hydroxylase C-terminal domain SPX PF03105.19 OAP58954.1 - 0.013 15.4 0.2 0.016 15.2 0.2 1.0 1 0 0 1 1 1 0 SPX domain DUF2730 PF10805.8 OAP58954.1 - 0.035 14.2 0.1 0.051 13.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) DivIC PF04977.15 OAP58954.1 - 0.041 13.7 1.0 0.072 12.9 1.0 1.4 1 0 0 1 1 1 0 Septum formation initiator BLOC1_2 PF10046.9 OAP58954.1 - 0.046 14.0 0.2 0.079 13.3 0.2 1.3 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 XhlA PF10779.9 OAP58954.1 - 0.28 11.4 1.1 0.54 10.5 1.1 1.4 1 0 0 1 1 1 0 Haemolysin XhlA Nsp1_C PF05064.13 OAP58955.1 - 6.3e-32 109.8 2.4 7.6e-32 109.6 0.3 2.0 2 0 0 2 2 2 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.6 OAP58955.1 - 0.0015 19.3 24.3 0.0015 19.3 24.3 6.6 1 1 5 6 6 6 3 Nucleoporin FG repeat region HAP1_N PF04849.13 OAP58955.1 - 0.068 12.4 4.3 0.078 12.2 0.6 2.1 2 0 0 2 2 2 0 HAP1 N-terminal conserved region Evr1_Alr PF04777.13 OAP58955.1 - 0.18 12.3 0.0 0.39 11.2 0.0 1.6 1 0 0 1 1 1 0 Erv1 / Alr family DUF724 PF05266.14 OAP58955.1 - 0.21 11.4 1.8 0.4 10.5 1.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF724) CCDC-167 PF15188.6 OAP58955.1 - 0.46 10.8 1.5 0.97 9.8 1.5 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 AAA_13 PF13166.6 OAP58955.1 - 1.2 7.7 3.5 2 6.9 1.9 1.9 1 1 1 2 2 2 0 AAA domain ERM PF00769.19 OAP58955.1 - 1.8 8.3 7.6 3 7.6 7.4 1.4 1 1 0 1 1 1 0 Ezrin/radixin/moesin family DUF5102 PF17104.5 OAP58956.1 - 8.8e-110 367.3 1.6 1.4e-109 366.6 1.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5102) Caskin-Pro-rich PF16907.5 OAP58956.1 - 0.023 15.2 0.8 0.095 13.2 0.8 2.1 1 0 0 1 1 1 0 Proline rich region of Caskin proteins FEZ PF07763.13 OAP58956.1 - 0.053 13.3 0.9 0.12 12.1 0.7 1.7 2 0 0 2 2 2 0 FEZ-like protein Zn_clus PF00172.18 OAP58957.1 - 2.1e-08 34.1 10.6 4.5e-08 33.1 10.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAP58957.1 - 2.2e-08 33.5 0.1 3.4e-08 32.8 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 OAP58958.1 - 8.7e-34 117.0 61.5 1.2e-30 106.6 39.5 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily CSN8_PSD8_EIF3K PF10075.9 OAP58959.1 - 7.4e-20 71.4 0.0 2e-18 66.7 0.0 2.1 2 0 0 2 2 2 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 OAP58959.1 - 0.0037 16.7 0.0 0.0087 15.5 0.0 1.6 2 0 0 2 2 2 1 SAC3/GANP family WD40 PF00400.32 OAP58961.1 - 1.6e-27 95.1 0.0 3.1e-08 34.1 0.0 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAP58961.1 - 5.1e-12 45.9 0.1 0.00091 19.5 0.1 4.9 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OAP58961.1 - 0.00098 19.1 0.3 0.37 10.6 0.0 3.4 1 1 3 4 4 4 2 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.6 OAP58961.1 - 0.0054 16.3 0.6 0.081 12.5 0.1 2.4 2 1 1 3 3 3 2 PQQ-like domain WD40_like PF17005.5 OAP58961.1 - 0.024 14.0 0.0 0.54 9.5 0.0 2.5 1 1 1 2 2 2 0 WD40-like domain PALB2_WD40 PF16756.5 OAP58961.1 - 0.08 11.9 0.0 2.5 6.9 0.0 2.2 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain SesA PF17107.5 OAP58962.1 - 0.16 12.2 0.0 0.4 10.9 0.0 1.6 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Patatin PF01734.22 OAP58963.1 - 5.3e-20 72.5 0.0 3.1e-19 70.0 0.0 2.3 2 1 0 2 2 2 1 Patatin-like phospholipase AAA_16 PF13191.6 OAP58963.1 - 2.8e-06 27.8 0.3 7e-05 23.3 0.0 3.1 3 1 1 4 4 4 1 AAA ATPase domain NB-ARC PF00931.22 OAP58963.1 - 7.9e-05 22.0 0.0 0.00015 21.0 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.6 OAP58963.1 - 0.0018 18.5 0.0 0.0092 16.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain ATPase PF06745.13 OAP58963.1 - 0.0024 17.2 0.1 0.061 12.7 0.0 3.1 4 0 0 4 4 4 1 KaiC AAA_24 PF13479.6 OAP58963.1 - 0.0088 15.8 0.0 0.023 14.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 OAP58963.1 - 0.01 15.8 0.0 0.079 13.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA PF00004.29 OAP58963.1 - 0.014 15.8 0.0 0.088 13.2 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 OAP58963.1 - 0.031 14.2 0.0 0.12 12.3 0.0 2.0 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_25 PF13481.6 OAP58963.1 - 0.044 13.3 0.0 0.12 11.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 OAP58963.1 - 0.045 13.8 0.1 0.35 10.9 0.0 2.5 4 0 0 4 4 4 0 AAA domain AAA_11 PF13086.6 OAP58963.1 - 0.094 12.5 0.2 0.52 10.1 0.0 2.2 3 0 0 3 3 3 0 AAA domain IstB_IS21 PF01695.17 OAP58963.1 - 0.11 12.2 0.0 0.39 10.4 0.0 2.0 2 1 0 2 2 2 0 IstB-like ATP binding protein p450 PF00067.22 OAP58964.1 - 1e-38 133.3 0.0 1.3e-38 132.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Amidase PF01425.21 OAP58965.1 - 1.5e-88 297.7 0.2 2.2e-88 297.2 0.2 1.2 1 1 0 1 1 1 1 Amidase Fungal_trans PF04082.18 OAP58966.1 - 1.8e-25 89.5 0.0 3.5e-25 88.5 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP58966.1 - 1.4e-08 34.7 9.3 2.7e-08 33.8 9.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aa_trans PF01490.18 OAP58967.1 - 1.2e-26 93.4 28.0 1.5e-26 93.1 28.0 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.6 OAP58967.1 - 0.4 9.5 44.1 28 3.4 44.1 2.3 1 1 0 1 1 1 0 Amino acid permease DUF805 PF05656.14 OAP58967.1 - 7.2 7.1 12.3 0.93 9.9 2.5 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF805) adh_short_C2 PF13561.6 OAP58968.1 - 3.3e-63 213.4 0.3 4.6e-63 212.9 0.3 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP58968.1 - 1.4e-50 171.5 0.0 1.8e-50 171.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAP58968.1 - 2.9e-09 37.1 1.0 5.5e-09 36.2 0.0 1.9 3 0 0 3 3 3 1 KR domain Polysacc_synt_2 PF02719.15 OAP58968.1 - 0.044 12.9 0.0 0.068 12.3 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein ThiF PF00899.21 OAP58968.1 - 0.063 12.6 2.8 0.57 9.5 0.3 2.4 1 1 1 2 2 2 0 ThiF family FTHFS PF01268.19 OAP58969.1 - 3.2e-255 847.6 0.0 4.4e-255 847.1 0.0 1.2 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 OAP58969.1 - 3.7e-67 224.6 0.9 3.7e-67 224.6 0.9 2.1 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 OAP58969.1 - 5e-39 133.2 0.4 1.1e-38 132.1 0.4 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GTP_EFTU PF00009.27 OAP58969.1 - 0.00096 18.7 0.2 0.003 17.1 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain OCD_Mu_crystall PF02423.15 OAP58969.1 - 0.0098 14.9 0.8 0.02 13.8 0.1 1.7 2 0 0 2 2 2 1 Ornithine cyclodeaminase/mu-crystallin family Helicase_C_4 PF13871.6 OAP58969.1 - 0.017 14.8 0.0 0.03 14.0 0.0 1.3 1 0 0 1 1 1 0 C-terminal domain on Strawberry notch homologue RsgA_GTPase PF03193.16 OAP58969.1 - 0.084 12.8 0.0 0.23 11.3 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase ABC2_membrane PF01061.24 OAP58970.1 - 1.2e-72 243.8 53.4 2.9e-40 137.9 18.5 2.6 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 OAP58970.1 - 9.7e-33 113.6 0.0 1.1e-17 64.8 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 OAP58970.1 - 3.4e-32 110.2 0.8 7.2e-28 96.3 0.1 2.8 2 0 0 2 2 2 2 CDR ABC transporter ABC2_membrane_3 PF12698.7 OAP58970.1 - 1.1e-07 31.3 3.4 1.1e-07 31.3 3.4 3.5 2 2 1 3 3 3 1 ABC-2 family transporter protein AAA_21 PF13304.6 OAP58970.1 - 1.3e-06 28.5 0.0 0.099 12.4 0.0 3.2 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OAP58970.1 - 0.00027 20.5 0.0 1.3 8.4 0.0 3.2 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 OAP58970.1 - 0.00047 20.6 1.6 0.0012 19.3 0.1 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 OAP58970.1 - 0.00095 19.5 0.4 0.0049 17.2 0.2 2.4 3 1 0 3 3 1 1 AAA domain AAA_25 PF13481.6 OAP58970.1 - 0.0011 18.5 0.0 0.0029 17.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 OAP58970.1 - 0.0016 18.4 0.0 0.0034 17.3 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase NACHT PF05729.12 OAP58970.1 - 0.0018 18.2 0.0 0.0044 16.9 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_29 PF13555.6 OAP58970.1 - 0.0031 17.2 0.3 0.02 14.6 0.1 2.5 3 0 0 3 3 2 1 P-loop containing region of AAA domain AAA_23 PF13476.6 OAP58970.1 - 0.0048 17.4 0.0 0.01 16.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 OAP58970.1 - 0.056 13.4 0.2 0.12 12.3 0.2 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 OAP58970.1 - 0.068 12.4 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.6 OAP58970.1 - 0.11 12.6 0.0 0.33 11.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 OAP58970.1 - 0.12 12.6 0.5 0.33 11.2 0.5 1.8 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 OAP58970.1 - 0.12 12.9 0.0 0.3 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 OAP58970.1 - 0.27 10.9 0.9 0.68 9.6 0.4 1.9 2 0 0 2 2 2 0 AAA domain Fungal_trans PF04082.18 OAP58971.1 - 2.6e-22 79.2 0.0 4.3e-22 78.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain LXG PF04740.12 OAP58971.1 - 0.014 15.1 0.1 0.43 10.3 0.0 2.4 2 0 0 2 2 2 0 LXG domain of WXG superfamily EHN PF06441.12 OAP58972.1 - 1.7e-32 112.0 0.3 2.5e-32 111.4 0.3 1.3 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 OAP58972.1 - 1.5e-14 54.3 0.1 3.4e-14 53.1 0.1 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF915 PF06028.11 OAP58972.1 - 0.0025 17.2 0.0 0.0037 16.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) CorA PF01544.18 OAP58974.1 - 3.8e-06 26.4 3.7 9.1e-06 25.2 0.1 2.2 1 1 1 2 2 2 2 CorA-like Mg2+ transporter protein CDP-OH_P_transf PF01066.21 OAP58975.1 - 6.1e-13 49.3 0.2 6.1e-13 49.3 0.2 1.8 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Gar1 PF04410.14 OAP58976.1 - 4e-38 130.6 0.0 6.4e-38 129.9 0.0 1.3 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region tRNA-synt_2b PF00587.25 OAP58977.1 - 9.6e-32 110.4 0.0 1.5e-28 100.0 0.0 2.9 3 0 0 3 3 3 2 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 OAP58977.1 - 1.6e-16 60.2 0.2 3.6e-16 59.1 0.2 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.14 OAP58977.1 - 8.3e-12 45.0 0.0 1.5e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.21 OAP58977.1 - 2.7e-05 24.1 0.0 0.00057 19.9 0.0 2.4 2 0 0 2 2 2 1 TGS domain DUF2370 PF10176.9 OAP58978.1 - 1.6e-89 299.5 0.0 2.8e-89 298.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) DUF2561 PF10812.8 OAP58978.1 - 0.32 11.0 0.8 0.56 10.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2561) Abhydrolase_6 PF12697.7 OAP58980.1 - 0.00012 22.7 0.8 0.00017 22.2 0.8 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF4054 PF13262.6 OAP58980.1 - 0.18 11.8 0.0 0.31 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4054) RRM_1 PF00076.22 OAP58981.1 - 2.6e-08 33.6 0.0 5.1e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OAP58981.1 - 8.1e-05 22.2 0.0 0.00018 21.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.15 OAP58981.1 - 0.21 11.6 0.0 0.73 9.9 0.0 1.9 2 0 0 2 2 2 0 DbpA RNA binding domain U3_assoc_6 PF08640.11 OAP58982.1 - 6.3e-29 99.9 0.4 1.2e-27 95.8 0.3 2.3 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.6 OAP58982.1 - 9.2e-06 26.1 2.8 0.015 16.0 0.4 3.9 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_15 PF13429.6 OAP58982.1 - 0.013 14.8 0.1 0.025 13.8 0.1 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat NRDE-2 PF08424.10 OAP58982.1 - 0.022 13.9 0.1 0.15 11.1 0.0 2.0 1 1 0 1 1 1 0 NRDE-2, necessary for RNA interference Frag1 PF10277.9 OAP58983.1 - 2.7e-40 138.2 7.6 2.7e-40 138.2 7.6 3.3 3 1 0 3 3 3 2 Frag1/DRAM/Sfk1 family Methyltransf_2 PF00891.18 OAP58985.1 - 9.8e-23 80.5 0.2 2.5e-22 79.2 0.2 1.7 1 1 0 1 1 1 1 O-methyltransferase domain Rrf2 PF02082.20 OAP58985.1 - 0.0099 16.2 0.0 0.023 15.0 0.0 1.6 1 0 0 1 1 1 1 Transcriptional regulator MarR PF01047.22 OAP58985.1 - 0.04 13.8 0.0 0.09 12.7 0.0 1.5 1 0 0 1 1 1 0 MarR family Methyltransf_25 PF13649.6 OAP58985.1 - 0.065 13.9 0.0 0.19 12.5 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Put_DNA-bind_N PF06971.13 OAP58985.1 - 0.077 13.0 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 Putative DNA-binding protein N-terminus Methyltransf_23 PF13489.6 OAP58985.1 - 0.11 12.3 0.0 0.33 10.8 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain p450 PF00067.22 OAP58986.1 - 5.4e-68 229.8 0.0 6.8e-68 229.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ADH_N PF08240.12 OAP58987.1 - 3.4e-06 26.9 0.1 8.2e-05 22.5 0.1 2.2 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAP58987.1 - 0.12 12.4 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase FAD_binding_4 PF01565.23 OAP58988.1 - 5.3e-21 74.8 1.9 1.1e-20 73.8 1.9 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 OAP58988.1 - 1.5e-07 31.4 0.1 3.2e-07 30.3 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like DNA_pol_viral_N PF00242.17 OAP58988.1 - 0.15 11.5 0.0 0.29 10.6 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain DIM PF08194.12 OAP58988.1 - 0.18 12.1 2.4 0.48 10.7 2.4 1.8 1 0 0 1 1 1 0 DIM protein SH2_2 PF14633.6 OAP58989.1 - 3.7e-84 281.5 0.0 3.7e-84 281.5 0.0 2.3 3 0 0 3 3 3 1 SH2 domain HTH_44 PF14641.6 OAP58989.1 - 3.2e-32 111.4 0.3 1.3e-31 109.4 0.3 2.1 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 HHH_7 PF14635.6 OAP58989.1 - 2.7e-30 104.8 0.0 5.7e-30 103.8 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.6 OAP58989.1 - 1.1e-25 90.2 0.0 3.8e-25 88.4 0.0 2.1 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 SPT6_acidic PF14632.6 OAP58989.1 - 1.9e-14 54.0 31.6 1.9e-14 54.0 31.6 6.0 3 1 4 7 7 7 1 Acidic N-terminal SPT6 HHH_9 PF17674.1 OAP58989.1 - 5e-06 27.3 1.9 5e-06 27.3 1.9 3.9 3 1 0 3 3 3 1 HHH domain SH2 PF00017.24 OAP58989.1 - 1.8e-05 24.8 0.0 4.6e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 SH2 domain HHH_3 PF12836.7 OAP58989.1 - 0.012 15.8 0.0 0.036 14.3 0.0 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix motif Pkinase PF00069.25 OAP58990.1 - 7.8e-63 212.3 0.0 1.4e-62 211.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain VHS PF00790.19 OAP58990.1 - 1.8e-43 147.8 0.0 3.9e-43 146.7 0.0 1.6 1 0 0 1 1 1 1 VHS domain Pkinase_Tyr PF07714.17 OAP58990.1 - 2e-33 115.8 0.0 3.2e-33 115.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Alpha_adaptinC2 PF02883.20 OAP58990.1 - 1.7e-24 86.2 1.4 4.3e-24 84.9 1.4 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain GAT PF03127.14 OAP58990.1 - 4.2e-21 75.0 0.1 1.2e-20 73.6 0.1 1.8 1 0 0 1 1 1 1 GAT domain GGA_N-GAT PF18308.1 OAP58990.1 - 5.4e-08 32.3 1.1 1.2e-06 28.0 0.0 3.2 3 0 0 3 3 3 1 GGA N-GAT domain Pkinase_fungal PF17667.1 OAP58990.1 - 0.00017 20.5 0.0 0.00031 19.6 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 OAP58990.1 - 0.00049 19.5 0.0 0.0011 18.4 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 OAP58990.1 - 0.081 12.0 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 PIN_8 PF18476.1 OAP58990.1 - 0.3 10.9 1.6 0.52 10.1 1.2 1.5 2 0 0 2 2 2 0 PIN like domain DUF5384 PF17358.2 OAP58991.1 - 0.29 11.2 9.2 0.53 10.3 9.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5384) GAS PF13851.6 OAP58992.1 - 0.12 11.7 3.1 0.34 10.2 1.9 2.0 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding CBS PF00571.28 OAP58993.1 - 1.5e-18 67.0 8.7 6.2e-06 26.6 0.0 5.1 5 0 0 5 5 5 4 CBS domain NP1-WLL PF11733.8 OAP58994.1 - 0.11 12.2 2.1 0.22 11.3 2.1 1.4 1 0 0 1 1 1 0 Non-capsid protein NP1 FAM60A PF15396.6 OAP58994.1 - 0.15 12.0 0.8 0.25 11.3 0.8 1.2 1 0 0 1 1 1 0 Protein Family FAM60A RBR PF17208.3 OAP58994.1 - 0.42 11.3 3.4 0.89 10.3 3.4 1.4 1 0 0 1 1 1 0 RNA binding Region SGL PF08450.12 OAP58995.1 - 5.7e-22 78.5 0.2 1.1e-21 77.6 0.2 1.5 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 OAP58995.1 - 8.2e-05 22.7 0.0 0.0014 18.8 0.0 2.6 1 1 1 2 2 2 1 Arylesterase Str_synth PF03088.16 OAP58995.1 - 0.00025 21.1 0.0 0.0012 18.9 0.0 2.1 1 1 0 1 1 1 1 Strictosidine synthase PD40 PF07676.12 OAP58995.1 - 0.25 11.3 1.2 2 8.5 0.1 3.0 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Pep_deformylase PF01327.21 OAP58996.1 - 1.4e-41 141.7 0.0 2.1e-41 141.2 0.0 1.2 1 0 0 1 1 1 1 Polypeptide deformylase HAD_2 PF13419.6 OAP58997.1 - 2.1e-12 47.5 0.0 2.9e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OAP58997.1 - 7.6e-08 32.9 0.0 2.8e-07 31.0 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OAP58997.1 - 0.00037 20.5 0.0 0.00074 19.5 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 OAP58997.1 - 0.029 14.5 0.0 0.13 12.3 0.0 2.2 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase EI24 PF07264.11 OAP58998.1 - 7.4e-15 55.6 15.4 9.8e-15 55.2 15.4 1.1 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) YqzE PF14038.6 OAP58998.1 - 0.12 12.4 0.1 0.26 11.3 0.1 1.5 1 0 0 1 1 1 0 YqzE-like protein Zn_clus PF00172.18 OAP58999.1 - 3.4e-08 33.5 9.9 5.9e-08 32.7 9.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAP58999.1 - 0.0055 15.8 0.0 0.027 13.5 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain HNH PF01844.23 OAP59000.1 - 0.1 12.8 5.7 0.3 11.3 5.7 1.8 1 0 0 1 1 1 0 HNH endonuclease HNH_5 PF14279.6 OAP59000.1 - 0.26 11.2 1.1 8.3 6.4 1.5 2.7 2 1 0 2 2 2 0 HNH endonuclease DUF3449 PF11931.8 OAP59001.1 - 0.0068 16.2 1.5 0.83 9.4 0.0 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF3449) zf-Sec23_Sec24 PF04810.15 OAP59001.1 - 0.14 12.2 0.5 6.3 6.9 0.1 2.6 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger zf-UBP PF02148.19 OAP59001.1 - 2.7 8.4 6.1 4.5 7.7 0.3 2.4 1 1 1 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein GMC_oxred_N PF00732.19 OAP59002.1 - 2.9e-76 256.7 0.0 3.7e-76 256.3 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAP59002.1 - 1.2e-33 116.6 0.0 4.9e-33 114.7 0.0 2.0 1 1 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 OAP59002.1 - 0.001 18.2 0.0 1.1 8.3 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 OAP59002.1 - 0.0019 17.3 0.0 0.0029 16.7 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 OAP59002.1 - 0.04 13.2 0.0 0.073 12.3 0.0 1.3 1 0 0 1 1 1 0 Thi4 family DAO PF01266.24 OAP59002.1 - 0.063 12.9 0.7 0.55 9.8 0.7 2.3 1 1 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAP59002.1 - 0.21 10.8 0.0 0.35 10.1 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase BCAS2 PF05700.11 OAP59003.1 - 1.5e-53 181.5 0.7 1.7e-53 181.4 0.7 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) Ceramidase_alk PF04734.13 OAP59004.1 - 3e-212 705.8 0.0 3.4e-212 705.6 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 OAP59004.1 - 7.3e-57 191.9 0.0 1.1e-56 191.4 0.0 1.3 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal Kelch_5 PF13854.6 OAP59005.1 - 5.4e-16 58.2 7.4 4.2e-07 29.8 0.0 4.7 4 0 0 4 4 4 3 Kelch motif Kelch_4 PF13418.6 OAP59005.1 - 1.9e-08 34.1 15.3 0.003 17.5 0.2 5.9 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_3 PF13415.6 OAP59005.1 - 1e-07 32.0 13.2 0.029 14.7 0.2 6.0 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_2 PF07646.15 OAP59005.1 - 5.6e-07 29.3 9.5 0.031 14.3 0.6 4.5 5 0 0 5 5 5 3 Kelch motif Kelch_1 PF01344.25 OAP59005.1 - 6.1e-06 25.7 6.4 0.095 12.3 0.1 3.9 3 0 0 3 3 3 3 Kelch motif Kelch_6 PF13964.6 OAP59005.1 - 3.7e-05 23.8 17.3 0.14 12.5 0.4 5.7 4 1 1 5 5 5 3 Kelch motif SKG6 PF08693.10 OAP59005.1 - 0.002 17.5 3.5 0.0061 15.9 3.5 1.8 1 0 0 1 1 1 1 Transmembrane alpha-helix domain MFS_1 PF07690.16 OAP59006.1 - 3.3e-36 125.0 35.2 1.1e-34 119.9 34.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAP59006.1 - 1.6e-10 40.5 9.4 1.6e-10 40.5 9.4 1.9 2 0 0 2 2 2 1 Sugar (and other) transporter HemY_N PF07219.13 OAP59006.1 - 0.017 15.3 0.1 0.069 13.4 0.1 2.1 1 0 0 1 1 1 0 HemY protein N-terminus QCR10 PF09796.9 OAP59006.1 - 1.3 9.1 3.7 22 5.2 0.4 2.9 2 0 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Ribosomal_L27A PF00828.19 OAP59008.1 - 7.2e-16 59.0 0.0 7.8e-16 58.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Drc1-Sld2 PF11719.8 OAP59009.1 - 1.2e-69 236.0 18.2 1.7e-69 235.5 18.2 1.2 1 0 0 1 1 1 1 DNA replication and checkpoint protein Sec1 PF00995.23 OAP59010.1 - 1.4e-124 417.4 0.0 1.7e-124 417.2 0.0 1.0 1 0 0 1 1 1 1 Sec1 family zf_CCCH_4 PF18345.1 OAP59011.1 - 2.7e-06 27.2 2.7 4.7e-06 26.5 2.7 1.4 1 0 0 1 1 1 1 Zinc finger domain Torus PF16131.5 OAP59011.1 - 0.00049 20.8 0.3 0.0016 19.1 0.3 1.9 1 0 0 1 1 1 1 Torus domain zf-CCCH_3 PF15663.5 OAP59011.1 - 0.0064 16.7 0.1 0.013 15.7 0.1 1.5 1 0 0 1 1 1 1 Zinc-finger containing family zf-CCCH PF00642.24 OAP59011.1 - 0.0097 15.8 0.8 0.016 15.1 0.8 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 OAP59011.1 - 0.036 13.9 1.4 0.067 13.0 1.4 1.4 1 0 0 1 1 1 0 CCCH-type zinc finger Med26 PF08711.11 OAP59011.1 - 0.06 13.4 0.3 0.21 11.6 0.2 1.9 2 0 0 2 2 2 0 TFIIS helical bundle-like domain zf-CCCH_2 PF14608.6 OAP59011.1 - 0.24 11.9 0.5 0.43 11.1 0.5 1.4 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger AT_hook PF02178.19 OAP59011.1 - 8.2 6.7 8.4 0.78 9.8 2.1 2.9 2 0 0 2 2 2 0 AT hook motif ArsA_ATPase PF02374.15 OAP59012.1 - 8.6e-114 379.8 0.0 9.9e-114 379.6 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 OAP59012.1 - 3.8e-15 56.2 0.0 2e-13 50.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain CbiA PF01656.23 OAP59012.1 - 1.1e-12 48.1 0.0 2.2e-12 47.2 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Fer4_NifH PF00142.18 OAP59012.1 - 1.5e-06 27.8 0.1 3.9e-06 26.5 0.0 1.7 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.22 OAP59012.1 - 2.5e-06 27.2 0.4 0.00045 19.9 0.1 2.5 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain ParA PF10609.9 OAP59012.1 - 7e-06 25.7 2.0 0.00011 21.7 0.1 2.6 3 0 0 3 3 3 1 NUBPL iron-transfer P-loop NTPase CBP_BcsQ PF06564.12 OAP59012.1 - 0.00013 21.5 0.3 0.00069 19.2 0.0 2.2 3 0 0 3 3 3 1 Cellulose biosynthesis protein BcsQ AAA_25 PF13481.6 OAP59012.1 - 0.0087 15.7 0.3 0.026 14.1 0.3 1.9 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 OAP59012.1 - 0.024 14.1 0.0 0.075 12.5 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein Zeta_toxin PF06414.12 OAP59012.1 - 0.026 13.8 0.0 0.046 13.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin NB-ARC PF00931.22 OAP59012.1 - 0.059 12.5 0.0 0.13 11.4 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain ATPase PF06745.13 OAP59012.1 - 0.094 12.0 0.2 0.31 10.3 0.0 1.8 2 0 0 2 2 2 0 KaiC AAA_16 PF13191.6 OAP59012.1 - 0.14 12.6 0.0 0.31 11.4 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain GREB1 PF15782.5 OAP59013.1 - 4.5 4.3 6.4 6.2 3.8 6.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer MFS_1 PF07690.16 OAP59014.1 - 4.5e-42 144.2 17.5 4.5e-42 144.2 17.5 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAP59014.1 - 6.6e-12 45.0 2.6 6.6e-12 45.0 2.6 3.1 3 1 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 OAP59014.1 - 1.1e-05 24.2 0.4 1.7e-05 23.5 0.4 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAP59015.1 - 5.5e-38 130.8 3.4 1.6e-21 76.6 0.8 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAP59015.1 - 5.8e-09 35.3 6.9 6.3e-06 25.3 2.1 3.0 3 0 0 3 3 3 2 Sugar (and other) transporter MFS_1_like PF12832.7 OAP59015.1 - 4e-07 29.2 8.1 4e-07 29.2 8.1 2.7 3 1 0 3 3 3 1 MFS_1 like family MFS_2 PF13347.6 OAP59015.1 - 1.2e-05 24.1 24.8 0.00082 18.0 14.0 3.4 2 2 1 3 3 3 3 MFS/sugar transport protein MFS_5 PF05631.14 OAP59015.1 - 0.00061 18.8 1.9 0.00098 18.1 1.9 1.2 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM FAM176 PF14851.6 OAP59015.1 - 0.0016 18.1 0.0 0.16 11.6 0.0 2.5 2 0 0 2 2 2 1 FAM176 family OATP PF03137.20 OAP59015.1 - 0.036 12.4 10.7 0.22 9.8 3.7 2.9 3 1 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family MFS_3 PF05977.13 OAP59015.1 - 0.52 8.6 10.7 0.22 9.9 1.8 2.2 2 0 0 2 2 2 0 Transmembrane secretion effector ECH_1 PF00378.20 OAP59016.1 - 2.2e-37 128.7 0.0 6.6e-37 127.2 0.0 1.6 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAP59016.1 - 4.9e-31 108.4 0.0 2.4e-30 106.2 0.0 1.7 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase MARVEL PF01284.23 OAP59017.1 - 1.2e-27 96.8 14.0 1.4e-27 96.5 14.0 1.0 1 0 0 1 1 1 1 Membrane-associating domain DUF2070 PF09843.9 OAP59017.1 - 0.087 11.1 4.1 0.091 11.0 4.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Pyr_redox_2 PF07992.14 OAP59018.1 - 1.6e-67 227.9 8.3 1.6e-67 227.9 8.3 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 OAP59018.1 - 2e-39 134.2 0.1 6.7e-39 132.6 0.1 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 OAP59018.1 - 3.9e-21 75.4 1.8 3.9e-21 75.4 1.8 2.9 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OAP59018.1 - 9.9e-09 34.7 7.0 8.8e-07 28.3 2.3 2.5 2 1 0 2 2 2 2 Glucose inhibited division protein A NAD_binding_8 PF13450.6 OAP59018.1 - 1.8e-07 31.2 4.1 0.0039 17.4 0.6 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 OAP59018.1 - 4.1e-07 29.7 9.8 5e-07 29.4 0.2 2.8 2 1 1 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 OAP59018.1 - 2e-06 27.3 0.3 2e-06 27.3 0.3 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAP59018.1 - 9.8e-06 24.5 14.0 0.0079 14.9 1.2 4.2 4 0 0 4 4 4 3 HI0933-like protein K_oxygenase PF13434.6 OAP59018.1 - 1.2e-05 24.6 0.1 0.094 11.8 0.0 2.3 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.24 OAP59018.1 - 3.2e-05 23.2 9.9 0.00011 21.4 2.0 3.2 3 1 0 3 3 3 1 FAD binding domain AlaDh_PNT_C PF01262.21 OAP59018.1 - 4.8e-05 22.8 3.7 0.0028 17.0 0.5 2.9 2 1 1 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 OAP59018.1 - 0.00076 19.2 12.1 0.36 10.4 1.9 4.1 4 0 0 4 4 4 2 FAD dependent oxidoreductase 3HCDH_N PF02737.18 OAP59018.1 - 0.054 13.4 1.8 0.13 12.1 1.8 1.7 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 OAP59018.1 - 0.078 13.4 0.8 0.73 10.3 0.2 2.6 2 0 0 2 2 2 0 Putative NAD(P)-binding Lycopene_cycl PF05834.12 OAP59018.1 - 0.31 10.0 4.6 4.8 6.1 0.5 2.7 2 1 0 2 2 2 0 Lycopene cyclase protein FAD_binding_3 PF01494.19 OAP59018.1 - 0.39 9.9 8.5 0.44 9.7 1.5 2.7 2 1 0 2 2 2 0 FAD binding domain GTP_EFTU PF00009.27 OAP59022.1 - 6.2e-32 110.7 4.6 3.4e-30 105.0 4.6 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 OAP59022.1 - 9e-24 83.6 0.6 2.5e-23 82.2 0.6 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 OAP59022.1 - 2.3e-08 34.1 0.2 5.7e-08 32.8 0.2 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 OAP59022.1 - 8.6e-07 29.3 0.8 0.0014 19.0 0.2 3.0 2 0 0 2 2 2 2 Elongation factor Tu domain 2 IF2_N PF04760.15 OAP59022.1 - 0.00017 21.3 0.0 0.0004 20.1 0.0 1.7 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region FeoB_N PF02421.18 OAP59022.1 - 0.00018 21.0 0.1 0.00035 20.1 0.1 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Arf PF00025.21 OAP59022.1 - 0.00056 19.4 0.0 0.0011 18.5 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OAP59022.1 - 0.0011 18.8 0.7 0.0084 16.0 0.2 2.2 1 1 1 2 2 2 1 RsgA GTPase Ras PF00071.22 OAP59022.1 - 0.002 17.7 0.1 0.0036 16.9 0.1 1.4 1 0 0 1 1 1 1 Ras family DUF2326 PF10088.9 OAP59022.1 - 0.02 14.7 0.3 0.039 13.7 0.3 1.4 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2326) SRPRB PF09439.10 OAP59022.1 - 0.05 13.0 0.1 0.13 11.7 0.1 1.6 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit TniB PF05621.11 OAP59022.1 - 0.063 12.7 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein Roc PF08477.13 OAP59022.1 - 0.11 12.8 0.1 0.19 11.9 0.1 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Mito_carr PF00153.27 OAP59023.1 - 3.2e-58 193.7 0.7 1.6e-19 69.6 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Fer4 PF00037.27 OAP59024.1 - 1.7e-13 49.8 16.1 2.1e-08 33.6 3.5 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 OAP59024.1 - 5.3e-13 49.3 8.7 8.9e-13 48.6 8.7 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 OAP59024.1 - 1.2e-09 38.9 6.4 3.4e-05 24.7 0.3 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 OAP59024.1 - 1.9e-09 37.5 4.5 0.00065 19.8 0.3 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 OAP59024.1 - 2.5e-09 37.1 20.5 1.2e-06 28.5 11.5 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 OAP59024.1 - 3.1e-08 33.7 9.2 5.1e-08 32.9 9.2 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 OAP59024.1 - 7e-08 32.8 18.9 1.3e-05 25.5 10.2 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 OAP59024.1 - 4e-06 26.6 11.7 0.0082 16.2 1.7 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 OAP59024.1 - 5.5e-06 26.5 9.7 0.00031 21.0 1.1 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.7 OAP59024.1 - 1.6e-05 24.7 16.3 0.0069 16.4 4.8 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 OAP59024.1 - 0.00019 21.9 11.6 0.0069 16.9 12.5 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_3 PF12798.7 OAP59024.1 - 0.0076 17.1 14.9 0.018 15.9 3.5 2.3 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_13 PF13370.6 OAP59024.1 - 0.012 16.1 14.4 0.33 11.5 3.6 2.6 2 1 1 3 3 3 0 4Fe-4S single cluster domain of Ferredoxin I c-SKI_SMAD_bind PF08782.10 OAP59024.1 - 0.031 14.5 4.7 1.4 9.2 0.3 2.2 1 1 1 2 2 2 0 c-SKI Smad4 binding domain Fer4_18 PF13746.6 OAP59024.1 - 0.11 12.7 8.9 65 3.8 8.6 2.2 1 1 0 1 1 1 0 4Fe-4S dicluster domain hGDE_central PF14702.6 OAP59024.1 - 0.17 11.5 0.0 0.25 11.0 0.0 1.1 1 0 0 1 1 1 0 Central domain of human glycogen debranching enzyme Fer4_22 PF17179.4 OAP59024.1 - 0.3 11.9 10.8 3 8.8 1.7 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain EPF PF17181.4 OAP59024.1 - 0.61 10.1 5.2 0.41 10.7 0.4 2.3 2 0 0 2 2 2 0 Epidermal patterning factor proteins ETF_QO PF05187.13 OAP59024.1 - 0.78 9.9 5.8 0.92 9.7 2.2 2.1 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_15 PF13459.6 OAP59024.1 - 1.3 9.9 11.8 7.6 7.4 4.3 3.0 2 1 0 2 2 2 0 4Fe-4S single cluster domain PP-binding PF00550.25 OAP59025.1 - 1.5e-10 41.3 0.2 2.1e-10 40.8 0.2 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 OAP59025.1 - 8.2e-07 29.2 0.1 1.7e-06 28.1 0.2 1.4 2 0 0 2 2 2 1 Acyl-carrier CoA_transf_3 PF02515.17 OAP59026.1 - 1.4e-108 363.3 0.1 1.7e-108 363.1 0.1 1.1 1 0 0 1 1 1 1 CoA-transferase family III Acyl-CoA_dh_1 PF00441.24 OAP59027.1 - 9.4e-36 123.3 9.6 2.1e-35 122.1 9.6 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 OAP59027.1 - 8.3e-23 81.2 0.2 8.3e-23 81.2 0.2 1.9 2 1 1 3 3 3 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 OAP59027.1 - 5e-18 65.1 0.0 9.2e-18 64.2 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 OAP59027.1 - 4e-14 53.0 6.1 4e-14 53.0 6.1 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Glucosaminidase PF01832.20 OAP59027.1 - 0.14 12.7 0.1 1.3 9.5 0.0 2.1 2 0 0 2 2 2 0 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase Rick_17kDa_Anti PF05433.15 OAP59028.1 - 0.0013 18.6 18.1 0.0013 18.6 18.1 1.8 2 0 0 2 2 2 1 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.6 OAP59028.1 - 0.0075 16.2 13.8 0.015 15.3 13.8 1.6 1 0 0 1 1 1 1 Glycine zipper Gly-zipper_YMGG PF13441.6 OAP59028.1 - 0.02 14.6 15.4 0.046 13.5 15.4 1.6 1 0 0 1 1 1 0 YMGG-like Gly-zipper DUF2076 PF09849.9 OAP59028.1 - 0.79 9.7 17.7 1.6 8.7 17.7 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) TraT PF05818.12 OAP59028.1 - 1.9 8.1 8.4 2.8 7.6 8.0 1.5 1 1 0 1 1 1 0 Enterobacterial TraT complement resistance protein DUF3425 PF11905.8 OAP59029.1 - 0.00018 21.4 0.0 0.00036 20.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Lbh PF15317.6 OAP59029.1 - 0.79 10.6 3.6 0.61 11.0 1.4 2.0 2 1 0 2 2 2 0 Cardiac transcription factor regulator, Developmental protein SnoaL_2 PF12680.7 OAP59030.1 - 0.011 16.4 0.0 0.014 16.1 0.0 1.1 1 0 0 1 1 1 0 SnoaL-like domain ADH_zinc_N PF00107.26 OAP59031.1 - 1.8e-21 76.4 0.0 3e-21 75.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAP59031.1 - 7.8e-17 62.6 0.0 1.1e-16 62.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAP59031.1 - 3.6e-08 33.3 0.0 1e-06 28.5 0.0 2.3 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain Rep_fac-A_C PF08646.10 OAP59032.1 - 2e-56 189.8 7.3 9.7e-55 184.3 2.6 2.5 3 0 0 3 3 3 2 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 OAP59032.1 - 2e-38 130.2 0.1 2e-37 127.0 0.1 2.4 2 0 0 2 2 2 1 Replication protein A OB domain Rep-A_N PF04057.12 OAP59032.1 - 6.2e-19 67.9 0.3 1.3e-18 66.9 0.3 1.5 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.25 OAP59032.1 - 8.7e-17 60.9 0.0 2.1e-10 40.4 0.0 3.8 3 0 0 3 3 3 3 OB-fold nucleic acid binding domain CDC24_OB3 PF17244.2 OAP59032.1 - 0.00013 21.7 0.4 0.016 15.0 0.1 3.0 3 0 0 3 3 3 1 Cell division control protein 24, OB domain 3 DUF4541 PF15074.6 OAP59032.1 - 0.058 14.0 0.3 0.37 11.4 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4541) DLH PF01738.18 OAP59033.1 - 9.3e-19 67.8 0.0 1.2e-09 38.1 0.0 2.5 2 1 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 OAP59033.1 - 0.00066 19.4 0.1 1.1 8.9 0.0 2.7 1 1 1 2 2 2 2 alpha/beta hydrolase fold EF-hand_1 PF00036.32 OAP59034.1 - 1.1e-41 137.3 12.9 7.8e-10 37.6 0.9 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 OAP59034.1 - 3.5e-36 123.5 5.8 3.9e-19 68.9 2.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 OAP59034.1 - 6.8e-35 118.7 11.4 2.3e-15 56.1 0.6 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 OAP59034.1 - 2.1e-30 102.0 9.5 1.9e-09 36.7 0.2 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 OAP59034.1 - 6.5e-26 88.6 10.6 2.6e-06 26.7 0.3 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 OAP59034.1 - 1.5e-16 60.5 0.4 2.3e-09 37.4 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 OAP59034.1 - 3.4e-09 36.6 1.9 0.00075 19.4 0.2 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 OAP59034.1 - 5.6e-09 36.3 0.2 0.0016 18.7 0.1 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.13 OAP59034.1 - 9.9e-07 28.7 0.0 0.0077 16.2 0.0 3.0 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.10 OAP59034.1 - 5.8e-06 26.3 1.6 2.3e-05 24.4 0.2 2.3 2 1 0 2 2 2 1 Ca2+ insensitive EF hand EF-hand_11 PF08976.11 OAP59034.1 - 9.1e-05 23.3 0.2 0.0022 18.8 0.1 2.0 1 1 1 2 2 2 1 EF-hand domain TerB PF05099.13 OAP59034.1 - 0.00012 22.0 0.3 0.35 10.8 0.0 2.2 1 1 1 2 2 2 2 Tellurite resistance protein TerB Caleosin PF05042.13 OAP59034.1 - 0.00045 20.2 1.8 0.44 10.5 0.0 3.5 1 1 3 4 4 4 1 Caleosin related protein RNA_pol_Rpb4 PF03874.16 OAP59034.1 - 0.00062 20.1 0.8 0.66 10.3 0.1 2.7 2 1 1 3 3 3 2 RNA polymerase Rpb4 DUF3349 PF11829.8 OAP59034.1 - 0.0014 19.3 0.4 3.7 8.4 0.0 2.9 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) Dockerin_1 PF00404.18 OAP59034.1 - 0.0053 16.9 7.0 0.38 11.0 0.8 2.9 1 1 2 3 3 3 2 Dockerin type I domain DUF5580 PF17743.1 OAP59034.1 - 0.006 15.2 0.0 0.0062 15.1 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5580) SurA_N_2 PF13623.6 OAP59034.1 - 0.0091 15.9 0.9 0.32 10.9 0.1 2.2 1 1 1 2 2 2 1 SurA N-terminal domain EF-hand_14 PF17959.1 OAP59034.1 - 0.012 16.0 0.5 6.2 7.2 0.1 2.4 1 1 1 2 2 2 0 EF-hand domain Poly_export PF02563.16 OAP59034.1 - 0.023 14.9 0.0 0.18 12.1 0.0 2.5 2 1 0 2 2 2 0 Polysaccharide biosynthesis/export protein DUF4497 PF14924.6 OAP59034.1 - 0.036 14.5 0.0 8.7 6.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4497) RuvA_C PF07499.13 OAP59034.1 - 0.058 13.9 0.1 8.5 6.9 0.0 3.0 3 0 0 3 3 3 0 RuvA, C-terminal domain MotA_activ PF09114.10 OAP59034.1 - 0.061 13.4 0.3 1.2 9.3 0.0 2.3 1 1 0 2 2 2 0 Transcription factor MotA, activation domain dCache_2 PF08269.11 OAP59034.1 - 0.066 12.4 0.1 1.1 8.4 0.1 2.1 1 1 1 2 2 2 0 Cache domain DUF5132 PF17195.4 OAP59034.1 - 0.15 12.2 0.5 21 5.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF5132) RloB PF13707.6 OAP59034.1 - 0.16 12.2 1.1 0.76 9.9 0.2 2.0 1 1 1 2 2 2 0 RloB-like protein SNARE PF05739.19 OAP59035.1 - 2.9e-15 56.0 1.3 1.3e-14 53.9 0.8 2.3 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.25 OAP59035.1 - 1.6e-06 28.0 10.7 7.3e-06 25.8 10.7 1.9 1 1 0 1 1 1 1 Syntaxin MCPsignal PF00015.21 OAP59035.1 - 0.0034 17.2 7.7 0.016 15.0 0.3 2.3 2 0 0 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain Med21 PF11221.8 OAP59035.1 - 0.0058 16.9 4.4 0.0089 16.3 0.1 2.5 2 1 0 2 2 2 1 Subunit 21 of Mediator complex DNA_repr_REX1B PF14966.6 OAP59035.1 - 0.011 16.3 2.8 0.035 14.8 0.3 2.8 2 1 1 3 3 3 0 DNA repair REX1-B MAP65_ASE1 PF03999.12 OAP59035.1 - 0.056 12.1 3.8 0.074 11.7 3.8 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Pox_VLTF3 PF04947.14 OAP59035.1 - 0.065 13.0 0.2 0.16 11.7 0.2 1.6 1 0 0 1 1 1 0 Poxvirus Late Transcription Factor VLTF3 like LXG PF04740.12 OAP59035.1 - 0.27 10.9 4.8 0.15 11.7 0.3 2.3 2 0 0 2 2 2 0 LXG domain of WXG superfamily Syntaxin_2 PF14523.6 OAP59035.1 - 0.27 11.6 14.8 0.13 12.6 7.3 2.9 2 2 0 2 2 2 0 Syntaxin-like protein TMPIT PF07851.13 OAP59035.1 - 0.38 10.0 6.2 0.56 9.4 2.1 2.1 2 0 0 2 2 2 0 TMPIT-like protein SlyX PF04102.12 OAP59035.1 - 0.47 11.1 8.0 0.76 10.4 0.3 3.2 2 1 1 3 3 3 0 SlyX DUF948 PF06103.11 OAP59035.1 - 2.5 8.4 6.0 30 5.0 0.1 3.4 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) HeLo PF14479.6 OAP59038.1 - 2.5e-05 24.2 0.0 0.00013 21.9 0.0 1.9 1 1 1 2 2 2 1 Prion-inhibition and propagation CENP-T_C PF15511.6 OAP59039.1 - 4.4e-09 36.4 0.1 5.3e-09 36.2 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 OAP59039.1 - 1.9e-05 25.1 0.2 2.2e-05 24.8 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 OAP59039.1 - 5e-05 23.4 0.2 7.3e-05 22.9 0.2 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 OAP59039.1 - 0.00012 22.3 0.1 0.00021 21.5 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 OAP59039.1 - 0.00017 21.9 0.1 0.00023 21.5 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 OAP59039.1 - 0.0038 17.3 0.0 0.0045 17.0 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 OAP59039.1 - 0.0045 17.0 0.0 0.0054 16.7 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated UPF0137 PF03677.13 OAP59039.1 - 0.05 13.4 0.2 0.061 13.1 0.2 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) TFIID_20kDa PF03847.13 OAP59039.1 - 0.059 13.9 0.0 0.12 12.9 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A HIGH_NTase1_ass PF16581.5 OAP59039.1 - 0.073 13.1 0.0 0.082 12.9 0.0 1.1 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region Lectin_leg-like PF03388.13 OAP59040.1 - 1.6e-58 197.8 0.0 1.9e-58 197.5 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.19 OAP59040.1 - 1.3e-06 28.1 0.0 0.0087 15.6 0.0 2.1 2 0 0 2 2 2 2 Legume lectin domain zf-Tim10_DDP PF02953.15 OAP59041.1 - 8.7e-21 73.3 1.3 1.5e-20 72.6 1.3 1.4 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Pkinase PF00069.25 OAP59042.1 - 4.6e-71 239.3 0.0 5.6e-71 239.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP59042.1 - 9e-38 130.0 0.0 1.2e-37 129.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAP59042.1 - 1e-05 25.0 0.0 1.5e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like CRIM PF16978.5 OAP59043.1 - 1.6e-41 141.8 0.0 2.7e-41 141.0 0.0 1.4 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), middle CRIM domain SIN1_PH PF16979.5 OAP59043.1 - 3.9e-20 72.2 0.1 6.3e-20 71.5 0.1 1.3 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology UCH PF00443.29 OAP59044.1 - 6.2e-35 120.9 0.0 1.1e-34 120.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 OAP59044.1 - 1.7e-25 89.1 10.4 1.6e-19 70.0 1.5 3.1 2 0 0 2 2 2 2 Zn-finger in ubiquitin-hydrolases and other protein zf-UBP_var PF17807.1 OAP59044.1 - 2e-25 88.3 3.2 1.2e-23 82.6 0.4 2.6 2 0 0 2 2 2 2 Variant UBP zinc finger UBA PF00627.31 OAP59044.1 - 1.4e-18 66.4 0.3 3.5e-11 42.8 0.1 2.7 2 0 0 2 2 2 2 UBA/TS-N domain UCH_1 PF13423.6 OAP59044.1 - 1.7e-15 57.5 1.6 6.7e-08 32.5 0.0 3.6 3 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase UBA_4 PF14555.6 OAP59044.1 - 0.0038 17.0 0.0 0.0079 16.0 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain DUF2180 PF09947.9 OAP59044.1 - 1.4 9.0 8.5 37 4.4 0.4 3.9 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2180) Tugs PF17840.1 OAP59045.1 - 0.057 13.6 0.4 0.13 12.5 0.4 1.6 1 1 0 1 1 1 0 Tethering Ubl4a to BAGS domain BOP1NT PF08145.12 OAP59046.1 - 2.7e-106 355.3 6.8 3.8e-106 354.8 6.8 1.2 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 OAP59046.1 - 9.1e-19 67.5 9.6 1.6e-07 31.9 0.6 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAP59046.1 - 0.0015 18.8 0.0 3.6 7.9 0.0 3.2 2 2 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain 4HBT PF03061.22 OAP59047.1 - 4.2e-14 52.7 0.1 6.7e-14 52.0 0.1 1.3 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.6 OAP59047.1 - 0.05 13.7 0.0 0.06 13.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) zf-RING_2 PF13639.6 OAP59048.1 - 0.036 14.4 3.3 0.036 14.4 3.3 1.7 2 0 0 2 2 2 0 Ring finger domain Ank_5 PF13857.6 OAP59048.1 - 0.044 14.1 0.0 0.5 10.7 0.0 2.3 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 OAP59048.1 - 0.19 12.3 0.0 0.9 10.2 0.0 2.0 2 1 0 2 2 2 0 Ankyrin repeats (3 copies) Cytochrome_C7 PF14522.6 OAP59048.1 - 0.22 11.6 3.1 0.34 11.0 3.1 1.3 1 0 0 1 1 1 0 Cytochrome c7 and related cytochrome c PXA PF02194.15 OAP59049.1 - 5.7e-38 130.7 0.2 1.1e-37 129.8 0.2 1.5 1 0 0 1 1 1 1 PXA domain Nexin_C PF08628.12 OAP59049.1 - 1.2e-20 74.1 0.0 3.3e-20 72.7 0.0 1.8 1 0 0 1 1 1 1 Sorting nexin C terminal PX PF00787.24 OAP59049.1 - 2e-07 31.0 0.0 7.2e-07 29.2 0.0 2.0 1 0 0 1 1 1 1 PX domain His_biosynth PF00977.21 OAP59050.1 - 1.5e-45 155.4 0.3 8e-45 153.1 0.3 2.2 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.28 OAP59050.1 - 2.3e-21 76.4 0.0 3.6e-21 75.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.19 OAP59050.1 - 2.8e-10 40.3 0.0 2.7e-07 30.6 0.0 2.3 2 0 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.14 OAP59050.1 - 1.3e-07 31.4 0.0 3.5e-07 30.0 0.0 1.8 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.13 OAP59050.1 - 0.019 14.7 0.3 0.12 12.1 0.0 2.3 2 1 0 2 2 2 0 Peptidase C26 Acyltransferase PF01553.21 OAP59051.1 - 1.5e-32 112.0 0.0 2.4e-32 111.4 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Rad52_Rad22 PF04098.15 OAP59052.1 - 1.4e-59 200.4 0.1 1.9e-59 200.0 0.1 1.2 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein DUF3433 PF11915.8 OAP59053.1 - 1.1e-36 125.2 16.1 1.4e-21 76.7 1.0 3.4 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) Amino_oxidase PF01593.24 OAP59054.1 - 3.6e-47 161.7 0.0 4.6e-47 161.3 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OAP59054.1 - 1.9e-06 28.0 0.0 5.2e-06 26.6 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAP59054.1 - 0.0081 15.4 0.0 0.013 14.7 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAP59054.1 - 0.025 13.7 0.4 0.035 13.2 0.4 1.2 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.24 OAP59054.1 - 0.028 14.0 0.2 0.056 13.0 0.2 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 OAP59054.1 - 0.043 12.5 0.2 0.067 11.9 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein p450 PF00067.22 OAP59055.1 - 1.2e-57 195.7 0.0 1.6e-57 195.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.25 OAP59055.1 - 4.6e-16 58.9 3.2 4.4e-13 49.1 0.3 3.1 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAP59055.1 - 3.3e-10 39.9 0.0 9.2e-10 38.5 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Iwr1 PF08574.10 OAP59056.1 - 2.4e-16 60.5 16.1 6e-16 59.2 15.5 2.1 2 0 0 2 2 2 1 Transcription factor Iwr1 ATP_sub_h PF10775.9 OAP59056.1 - 0.0083 16.1 1.6 0.015 15.3 0.0 2.2 3 0 0 3 3 3 1 ATP synthase complex subunit h Bcr-Abl_Oligo PF09036.10 OAP59056.1 - 0.078 13.0 0.0 0.26 11.3 0.0 1.8 1 0 0 1 1 1 0 Bcr-Abl oncoprotein oligomerisation domain PUF PF00806.19 OAP59058.1 - 1.7e-30 103.0 0.0 2.3e-05 23.8 0.0 6.7 6 0 0 6 6 6 6 Pumilio-family RNA binding repeat RRM_1 PF00076.22 OAP59058.1 - 2.6e-12 46.4 0.0 6.8e-12 45.0 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OAP59058.1 - 0.04 13.8 0.0 0.091 12.6 0.0 1.6 1 0 0 1 1 1 0 Occluded RNA-recognition motif SET_assoc PF11767.8 OAP59058.1 - 0.12 12.0 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated Myb_DNA-binding PF00249.31 OAP59059.1 - 2.5e-14 53.2 0.3 2.9e-06 27.4 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OAP59059.1 - 9.4e-12 45.0 0.0 5e-05 23.5 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain CHDCT2 PF08074.11 OAP59059.1 - 0.0013 18.9 0.0 0.13 12.4 0.0 2.3 2 0 0 2 2 2 1 CHDCT2 (NUC038) domain SANT_DAMP1_like PF16282.5 OAP59059.1 - 0.0018 18.4 0.4 0.66 10.2 0.1 2.3 2 0 0 2 2 2 2 SANT/Myb-like domain of DAMP1 SLIDE PF09111.10 OAP59059.1 - 0.027 14.5 0.0 7.4 6.6 0.0 2.3 2 0 0 2 2 2 0 SLIDE PX PF00787.24 OAP59060.1 - 9.3e-26 90.0 0.1 1.1e-25 89.8 0.1 1.1 1 0 0 1 1 1 1 PX domain DNA_pol_phi PF04931.13 OAP59061.1 - 6.1e-174 580.2 21.2 8.1e-174 579.8 21.2 1.2 1 0 0 1 1 1 1 DNA polymerase phi BUD22 PF09073.10 OAP59061.1 - 0.62 9.3 22.9 1.2 8.4 22.9 1.4 1 0 0 1 1 1 0 BUD22 Thioredoxin_16 PF18569.1 OAP59061.1 - 0.7 10.0 2.6 22 5.3 0.3 3.5 3 0 0 3 3 3 0 Thioredoxin-like domain ArAE_2_N PF10337.9 OAP59062.1 - 2.4e-31 109.3 3.4 2.4e-31 109.3 3.4 3.5 3 2 0 3 3 3 2 Putative ER transporter, 6TM, N-terminal FUSC_2 PF13515.6 OAP59062.1 - 2.5e-15 56.7 10.8 2.5e-15 56.7 10.8 3.1 2 1 1 3 3 3 1 Fusaric acid resistance protein-like ArAE_2 PF10334.9 OAP59062.1 - 4.5e-08 33.2 0.2 1.9e-06 27.9 0.1 2.5 2 1 0 2 2 2 1 Aromatic acid exporter family member 2 Methyltransf_23 PF13489.6 OAP59063.1 - 4.4e-27 94.9 0.0 6.1e-27 94.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAP59063.1 - 4.8e-13 49.6 0.0 1.1e-12 48.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAP59063.1 - 1.1e-09 38.8 0.0 2.9e-09 37.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAP59063.1 - 2.3e-09 37.2 0.0 1.1e-08 35.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAP59063.1 - 1.3e-08 35.5 0.0 7.1e-08 33.1 0.0 2.2 2 1 0 2 2 1 1 Methyltransferase domain FtsJ PF01728.19 OAP59063.1 - 7.5e-05 22.9 0.0 0.00011 22.4 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.14 OAP59063.1 - 0.0012 18.5 0.0 0.0019 17.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 OAP59063.1 - 0.004 16.5 0.0 0.015 14.7 0.0 1.8 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 OAP59063.1 - 0.0076 15.7 0.5 0.038 13.5 0.0 2.3 2 1 1 3 3 3 1 Putative methyltransferase Methyltransf_16 PF10294.9 OAP59063.1 - 0.025 14.3 0.0 0.039 13.7 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase Met_10 PF02475.16 OAP59063.1 - 0.032 14.0 0.0 0.045 13.5 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein CheR PF01739.18 OAP59063.1 - 0.099 12.1 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain FAD_binding_3 PF01494.19 OAP59064.1 - 6.3e-26 91.4 0.1 6e-11 42.2 0.0 3.1 3 0 0 3 3 3 3 FAD binding domain Pyr_redox PF00070.27 OAP59064.1 - 9.8e-05 22.8 0.0 0.049 14.2 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAP59064.1 - 0.00013 21.3 0.1 0.018 14.3 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAP59064.1 - 0.00024 21.3 0.0 0.0006 20.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAP59064.1 - 0.00036 20.2 0.1 0.009 15.6 0.0 2.2 1 1 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 OAP59064.1 - 0.00076 18.6 0.1 0.095 11.7 0.0 2.8 3 0 0 3 3 3 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 OAP59064.1 - 0.029 13.5 0.0 0.051 12.6 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 OAP59064.1 - 0.036 12.8 0.0 0.077 11.7 0.0 1.5 2 0 0 2 2 2 0 HI0933-like protein IlvN PF07991.12 OAP59064.1 - 0.037 13.6 0.0 0.074 12.6 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain ApbA PF02558.16 OAP59064.1 - 0.068 12.8 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.23 OAP59064.1 - 0.15 12.0 0.0 0.34 10.9 0.0 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus TrkA_N PF02254.18 OAP59064.1 - 0.2 11.9 0.0 0.38 11.0 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox_3 PF13738.6 OAP59064.1 - 0.2 10.9 0.0 0.38 10.0 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAP59065.1 - 6.3e-59 200.3 0.8 7.6e-59 200.0 0.8 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAP59065.1 - 0.00014 22.0 0.4 0.00034 20.8 0.4 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 OAP59065.1 - 0.0073 15.6 0.1 0.015 14.5 0.1 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 OAP59065.1 - 0.035 13.3 0.2 0.08 12.2 0.1 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 OAP59065.1 - 0.042 13.1 0.2 0.075 12.3 0.2 1.4 1 0 0 1 1 1 0 FAD binding domain ApbA PF02558.16 OAP59065.1 - 0.045 13.4 0.2 0.085 12.5 0.2 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.6 OAP59065.1 - 0.048 12.9 0.3 0.073 12.3 0.3 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAP59065.1 - 0.062 12.0 0.3 0.093 11.4 0.3 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.27 OAP59065.1 - 0.064 13.8 0.2 0.15 12.6 0.2 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 OAP59065.1 - 0.072 13.3 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Lycopene_cycl PF05834.12 OAP59065.1 - 0.099 11.7 0.8 0.36 9.8 0.4 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_oxidored PF12831.7 OAP59065.1 - 0.12 11.7 4.2 0.72 9.1 4.2 1.9 1 1 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 OAP59065.1 - 0.13 12.3 0.2 0.23 11.4 0.2 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 OAP59065.1 - 0.43 9.6 2.5 0.91 8.5 2.5 1.4 1 0 0 1 1 1 0 FAD binding domain TauD PF02668.16 OAP59066.1 - 1.7e-49 169.0 1.1 2.5e-49 168.5 1.1 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family K_channel_TID PF07941.11 OAP59066.1 - 0.012 16.0 3.0 0.022 15.2 3.0 1.3 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain p450 PF00067.22 OAP59067.1 - 2e-55 188.4 0.0 2.8e-55 187.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF4022 PF13214.6 OAP59067.1 - 0.14 12.4 0.8 0.46 10.8 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4022) GTP_EFTU PF00009.27 OAP59068.1 - 1.1e-32 113.2 0.5 4.7e-32 111.1 0.0 2.4 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 OAP59068.1 - 1.1e-20 73.7 0.2 3.1e-20 72.3 0.2 1.8 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 OAP59068.1 - 1.2e-10 41.6 3.0 1.1e-09 38.6 0.0 3.1 3 0 0 3 3 3 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.6 OAP59068.1 - 2.4e-09 36.9 0.2 9.1e-09 35.1 0.2 2.0 1 1 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.23 OAP59068.1 - 3.4e-07 30.3 0.3 9.6e-06 25.7 0.0 3.2 3 0 0 3 3 3 1 50S ribosome-binding GTPase Roc PF08477.13 OAP59068.1 - 0.00054 20.2 0.0 0.0015 18.8 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 OAP59068.1 - 0.0032 17.3 0.0 0.0092 15.8 0.0 1.9 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein MMS1_N PF10433.9 OAP59069.1 - 2.1e-41 142.1 0.0 1.9e-40 139.0 0.0 2.1 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term RabGAP-TBC PF00566.18 OAP59070.1 - 2.2e-20 73.2 0.1 4.4e-20 72.3 0.0 1.5 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Prefoldin_2 PF01920.20 OAP59070.1 - 0.096 12.7 0.1 0.23 11.4 0.1 1.6 1 0 0 1 1 1 0 Prefoldin subunit Yip1 PF04893.17 OAP59071.1 - 3.7e-11 43.0 14.0 5.8e-11 42.4 14.0 1.4 1 1 0 1 1 1 1 Yip1 domain YIF1 PF03878.15 OAP59071.1 - 0.044 13.3 2.9 0.56 9.7 2.9 2.2 1 1 0 1 1 1 0 YIF1 V_ATPase_I PF01496.19 OAP59072.1 - 1.8e-256 853.1 0.0 2.3e-256 852.8 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family ubiquitin PF00240.23 OAP59072.1 - 7.8e-33 112.1 0.6 1.6e-32 111.1 0.6 1.6 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.17 OAP59072.1 - 1.3e-30 105.0 11.9 2.2e-30 104.3 11.9 1.4 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.8 OAP59072.1 - 7.4e-15 54.6 1.3 1.8e-14 53.3 0.6 2.1 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 OAP59072.1 - 0.0004 20.8 0.2 0.0015 18.9 0.2 2.0 1 0 0 1 1 1 1 Ubiquitin-like domain CheZ PF04344.13 OAP59072.1 - 0.0084 16.1 1.4 0.038 13.9 0.1 2.3 2 0 0 2 2 2 1 Chemotaxis phosphatase, CheZ Filament PF00038.21 OAP59072.1 - 0.011 15.4 4.2 1.4 8.4 0.9 2.4 2 0 0 2 2 2 0 Intermediate filament protein TBK1_ULD PF18396.1 OAP59072.1 - 0.044 13.7 0.1 0.1 12.5 0.1 1.6 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 OAP59072.1 - 0.063 13.6 0.2 0.14 12.5 0.2 1.6 1 0 0 1 1 1 0 Ubiquitin-like domain DUF5344 PF17279.2 OAP59072.1 - 0.097 13.3 0.4 27 5.4 0.0 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5344) Baculo_PEP_C PF04513.12 OAP59072.1 - 0.098 12.7 1.2 0.41 10.7 0.2 2.4 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Prefoldin_2 PF01920.20 OAP59072.1 - 1.7 8.7 5.1 0.95 9.5 0.6 2.7 3 0 0 3 3 3 0 Prefoldin subunit BLM10_mid PF16507.5 OAP59073.1 - 4.5e-207 688.9 0.0 7.4e-207 688.2 0.0 1.4 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 OAP59073.1 - 4e-29 100.4 0.0 1.6e-28 98.4 0.0 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) BLM10_N PF16547.5 OAP59073.1 - 4.5e-21 74.9 0.0 1e-20 73.8 0.0 1.6 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, N-terminal HEAT PF02985.22 OAP59073.1 - 2.4e-05 24.2 0.1 0.9 10.0 0.0 4.5 3 0 0 3 3 3 1 HEAT repeat CLASP_N PF12348.8 OAP59073.1 - 0.0011 18.6 0.1 0.13 11.8 0.0 2.9 3 0 0 3 3 3 1 CLASP N terminal HEAT_2 PF13646.6 OAP59073.1 - 0.0081 16.5 0.0 1.1 9.7 0.0 3.9 4 0 0 4 4 4 1 HEAT repeats Isochorismatase PF00857.20 OAP59074.1 - 4.7e-20 72.5 0.0 5.4e-20 72.3 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family Sugar_tr PF00083.24 OAP59075.1 - 3.1e-62 210.9 25.8 8.8e-62 209.4 25.8 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP59075.1 - 6.4e-14 51.6 30.8 1.2e-13 50.7 30.8 1.5 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAP59076.1 - 4.4e-135 451.0 28.0 5.1e-135 450.8 28.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP59076.1 - 5.7e-25 88.0 46.8 6.1e-23 81.3 28.3 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily PAP2 PF01569.21 OAP59076.1 - 4.2 7.1 16.4 0.17 11.7 5.5 3.1 2 2 0 2 2 2 0 PAP2 superfamily PMT PF02366.18 OAP59077.1 - 0.016 14.8 5.1 0.024 14.2 4.6 1.7 1 1 0 1 1 1 0 Dolichyl-phosphate-mannose-protein mannosyltransferase AA_permease_2 PF13520.6 OAP59078.1 - 1.5e-48 165.7 48.6 1.8e-48 165.5 48.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAP59078.1 - 1e-24 87.0 41.5 1.3e-24 86.6 41.5 1.1 1 0 0 1 1 1 1 Amino acid permease DUF641 PF04859.12 OAP59079.1 - 0.035 14.5 0.1 0.077 13.3 0.1 1.6 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) PKcGMP_CC PF16808.5 OAP59079.1 - 0.044 13.6 1.9 0.1 12.5 1.9 1.6 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase XhlA PF10779.9 OAP59079.1 - 0.046 13.9 0.3 0.096 12.9 0.3 1.5 1 0 0 1 1 1 0 Haemolysin XhlA Prefoldin_2 PF01920.20 OAP59079.1 - 0.24 11.4 2.0 5.5 7.0 0.8 2.8 3 0 0 3 3 3 0 Prefoldin subunit Acyl_transf_3 PF01757.22 OAP59080.1 - 7.6e-39 133.7 24.4 9.7e-39 133.4 24.4 1.1 1 0 0 1 1 1 1 Acyltransferase family FAD-oxidase_C PF02913.19 OAP59081.1 - 1.5e-63 214.8 0.0 2.2e-63 214.2 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 OAP59081.1 - 1.6e-33 115.4 0.0 6.8e-33 113.3 0.0 2.1 3 0 0 3 3 3 1 FAD binding domain RdRP PF05183.12 OAP59082.1 - 5e-182 606.6 0.0 6.3e-182 606.3 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase RRM_1 PF00076.22 OAP59082.1 - 0.006 16.4 0.0 0.027 14.3 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L21e PF01157.18 OAP59083.1 - 2e-47 159.2 7.1 2.6e-47 158.8 5.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L21e LRS4 PF10422.9 OAP59083.1 - 0.022 14.3 0.0 0.027 14.1 0.0 1.1 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 S4 PF01479.25 OAP59084.1 - 2.1e-12 46.6 0.7 2.1e-12 46.6 0.7 2.5 3 0 0 3 3 3 1 S4 domain Ribosomal_S4 PF00163.19 OAP59084.1 - 7.6e-06 26.8 0.2 1.6e-05 25.7 0.2 1.6 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain DUF4201 PF13870.6 OAP59085.1 - 4.7e-05 23.2 4.7 0.14 11.9 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4201) AAA_13 PF13166.6 OAP59085.1 - 0.00014 20.7 3.2 0.00017 20.5 3.2 1.1 1 0 0 1 1 1 1 AAA domain HMMR_N PF15905.5 OAP59085.1 - 0.00066 19.3 5.4 0.00066 19.3 5.4 1.5 1 1 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal KxDL PF10241.9 OAP59085.1 - 0.0012 19.1 3.3 0.033 14.5 0.0 2.6 2 0 0 2 2 2 1 Uncharacterized conserved protein CENP-F_leu_zip PF10473.9 OAP59085.1 - 0.0024 17.9 2.6 0.0024 17.9 2.6 3.0 2 1 1 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4763 PF15960.5 OAP59085.1 - 0.0028 17.0 7.4 0.0074 15.6 7.4 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4763) DUF4407 PF14362.6 OAP59085.1 - 0.0033 16.8 3.3 0.0033 16.8 3.3 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF4407) DUF948 PF06103.11 OAP59085.1 - 0.0057 16.9 3.0 0.3 11.4 0.1 2.3 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF948) Mod_r PF07200.13 OAP59085.1 - 0.0094 16.1 8.3 0.017 15.2 0.6 2.5 2 1 0 2 2 2 1 Modifier of rudimentary (Mod(r)) protein Spc7 PF08317.11 OAP59085.1 - 0.011 14.7 17.5 0.15 10.9 1.4 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF1664 PF07889.12 OAP59085.1 - 0.012 15.6 5.3 0.27 11.3 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Bacillus_HBL PF05791.11 OAP59085.1 - 0.022 14.6 0.6 0.17 11.7 0.0 2.1 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Fez1 PF06818.15 OAP59085.1 - 0.024 15.1 12.3 0.045 14.2 12.3 1.4 1 0 0 1 1 1 0 Fez1 LidA_Long_CC PF18641.1 OAP59085.1 - 0.029 14.4 5.8 1.3 9.1 0.2 2.5 2 0 0 2 2 2 0 LidA long coiled-coil domain DUF641 PF04859.12 OAP59085.1 - 0.032 14.6 16.4 1.9 8.8 5.1 3.3 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) UPF0242 PF06785.11 OAP59085.1 - 0.033 14.3 8.6 1.6 8.8 0.1 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus L31 PF09784.9 OAP59085.1 - 0.042 14.3 3.1 0.06 13.8 0.7 2.1 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L31 DUF489 PF04356.12 OAP59085.1 - 0.087 12.8 3.5 0.23 11.4 0.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF489) DUF3584 PF12128.8 OAP59085.1 - 0.093 10.2 10.8 0.12 9.9 10.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Lipoprotein_7 PF01540.16 OAP59085.1 - 0.099 11.9 3.6 0.25 10.6 3.6 1.6 1 1 0 1 1 1 0 Adhesin lipoprotein TraB PF01963.17 OAP59085.1 - 0.12 12.2 6.5 0.54 10.1 5.7 2.0 1 1 1 2 2 2 0 TraB family Bap31_Bap29_C PF18035.1 OAP59085.1 - 0.13 12.3 8.8 0.45 10.6 0.1 3.5 2 1 1 3 3 3 0 Bap31/Bap29 cytoplasmic coiled-coil domain YabA PF06156.13 OAP59085.1 - 0.13 12.9 6.6 6.5 7.5 0.1 2.8 1 1 2 3 3 3 0 Initiation control protein YabA HIP1_clath_bdg PF16515.5 OAP59085.1 - 0.27 11.9 14.6 0.17 12.5 1.0 3.1 2 1 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 FlaC_arch PF05377.11 OAP59085.1 - 0.3 11.5 9.7 2.7 8.5 0.2 4.1 2 2 1 3 3 3 0 Flagella accessory protein C (FlaC) FUSC PF04632.12 OAP59085.1 - 0.33 9.5 5.5 0.41 9.1 4.8 1.5 1 1 0 1 1 1 0 Fusaric acid resistance protein family BLOC1_2 PF10046.9 OAP59085.1 - 0.38 11.1 6.4 1.2 9.5 0.3 2.6 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CHASE3 PF05227.13 OAP59085.1 - 0.41 10.6 12.6 0.19 11.6 0.5 2.3 2 0 0 2 2 2 0 CHASE3 domain DUF4094 PF13334.6 OAP59085.1 - 0.6 10.6 2.6 4.5 7.8 0.3 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4094) GAS PF13851.6 OAP59085.1 - 0.63 9.3 15.2 3 7.1 4.2 3.0 2 1 0 3 3 3 0 Growth-arrest specific micro-tubule binding OmpH PF03938.14 OAP59085.1 - 0.65 10.3 15.7 1.7 9.0 7.8 2.8 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) ABC_tran_CTD PF16326.5 OAP59085.1 - 0.72 10.1 0.0 0.72 10.1 0.0 4.1 3 1 0 3 3 3 0 ABC transporter C-terminal domain ATG16 PF08614.11 OAP59085.1 - 1.1 9.4 25.7 0.27 11.4 2.1 3.0 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) COG2 PF06148.11 OAP59085.1 - 1.1 9.3 11.7 1.3 9.1 0.9 3.0 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Cep57_CLD_2 PF14197.6 OAP59085.1 - 1.3 9.2 21.0 0.36 11.0 1.3 3.8 2 2 1 3 3 2 0 Centrosome localisation domain of PPC89 Phage_GPO PF05929.11 OAP59085.1 - 1.3 8.6 11.7 0.83 9.2 2.0 2.8 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase SlyX PF04102.12 OAP59085.1 - 1.5 9.5 14.0 25 5.6 5.7 3.7 2 1 0 3 3 3 0 SlyX Cnn_1N PF07989.11 OAP59085.1 - 2 8.6 16.7 3.8 7.8 0.8 3.9 2 2 2 4 4 4 0 Centrosomin N-terminal motif 1 DUF4200 PF13863.6 OAP59085.1 - 2.8 8.4 19.0 5.7 7.4 4.0 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) DivIC PF04977.15 OAP59085.1 - 2.9 7.7 20.3 5.9 6.7 0.0 4.3 3 1 1 4 4 4 0 Septum formation initiator Prefoldin_2 PF01920.20 OAP59085.1 - 3.2 7.8 15.0 1.5 8.8 2.8 2.9 2 1 0 2 2 2 0 Prefoldin subunit UPF0449 PF15136.6 OAP59085.1 - 4.6 7.8 7.5 4.8 7.7 0.7 3.0 1 1 2 3 3 3 0 Uncharacterised protein family UPF0449 Uds1 PF15456.6 OAP59085.1 - 8.3 6.6 14.7 5.9 7.1 8.2 2.6 2 1 0 2 2 2 0 Up-regulated During Septation FAM76 PF16046.5 OAP59085.1 - 8.5 5.6 9.8 8.1 5.7 0.7 2.1 1 1 1 2 2 2 0 FAM76 protein WDCP PF15390.6 OAP59085.1 - 9.6 4.4 6.4 15 3.8 5.6 1.6 1 1 1 2 2 2 0 WD repeat and coiled-coil-containing protein family DUF1797 PF08796.10 OAP59086.1 - 5.3 7.2 9.7 6 7.0 0.2 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1797) Mito_carr PF00153.27 OAP59087.1 - 9.3e-73 240.2 1.6 4.6e-25 87.4 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 OAP59087.1 - 0.034 13.3 0.4 13 4.8 0.1 3.5 3 2 0 4 4 4 0 Gammaproteobacterial serine protease CN_hydrolase PF00795.22 OAP59088.1 - 1.4e-35 122.9 0.0 3.8e-35 121.5 0.0 1.7 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase Acyl-CoA_dh_1 PF00441.24 OAP59089.1 - 5.3e-29 101.4 0.6 8.6e-29 100.7 0.6 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 OAP59089.1 - 1e-19 70.5 0.0 1.8e-19 69.7 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 OAP59089.1 - 1.6e-16 61.0 0.0 4.3e-16 59.6 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 OAP59089.1 - 2.2e-12 47.4 1.0 3.6e-12 46.7 1.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain SWIRM-assoc_3 PF16498.5 OAP59089.1 - 0.087 13.1 1.7 0.47 10.7 0.0 3.0 3 1 1 4 4 4 0 SWIRM-associated domain at the C-terminal bZIP_1 PF00170.21 OAP59090.1 - 0.091 12.9 5.6 0.19 11.9 5.6 1.4 1 0 0 1 1 1 0 bZIP transcription factor SBF PF01758.16 OAP59091.1 - 6.5e-53 179.3 8.2 6.5e-53 179.3 8.2 2.3 2 2 1 3 3 3 1 Sodium Bile acid symporter family FA_hydroxylase PF04116.13 OAP59091.1 - 0.93 9.8 3.1 0.96 9.8 0.4 2.5 2 1 0 2 2 2 0 Fatty acid hydroxylase superfamily DUF1793 PF08760.11 OAP59092.1 - 2.3e-69 233.1 0.7 5.4e-69 231.9 0.7 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) DUF4965 PF16335.5 OAP59092.1 - 4.2e-61 205.6 0.2 9.9e-48 162.1 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4965) DUF5127 PF17168.4 OAP59092.1 - 3.6e-47 161.0 0.8 5.9e-47 160.3 0.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4964 PF16334.5 OAP59092.1 - 0.0012 18.3 0.0 0.0025 17.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4964) Pyr_redox_2 PF07992.14 OAP59093.1 - 2.2e-05 23.9 0.0 0.002 17.4 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Acid_PPase PF12689.7 OAP59094.1 - 8.2e-56 188.5 0.0 1.2e-55 188.0 0.0 1.2 1 0 0 1 1 1 1 Acid Phosphatase Ank_5 PF13857.6 OAP59095.1 - 1.6e-34 117.5 9.4 2.3e-07 30.9 0.0 7.2 5 2 2 7 7 6 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 OAP59095.1 - 5e-32 110.3 4.4 1.8e-10 41.3 0.1 6.2 3 1 4 7 7 7 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAP59095.1 - 7.3e-30 103.0 3.7 1.1e-07 32.2 0.0 8.3 4 2 4 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAP59095.1 - 1e-23 80.8 8.4 0.001 19.4 0.0 10.6 11 0 0 11 11 10 6 Ankyrin repeat Ank PF00023.30 OAP59095.1 - 2.5e-15 56.1 14.7 0.0042 17.5 0.0 9.9 10 1 0 10 10 10 3 Ankyrin repeat SPRY PF00622.28 OAP59095.1 - 1.8e-14 53.9 0.0 4e-14 52.8 0.0 1.7 1 0 0 1 1 1 1 SPRY domain NACHT PF05729.12 OAP59095.1 - 1.2e-08 35.1 0.0 2.9e-08 33.8 0.0 1.8 1 0 0 1 1 1 1 NACHT domain KAP_NTPase PF07693.14 OAP59095.1 - 1e-06 28.3 0.3 0.00055 19.3 0.3 2.5 1 1 0 1 1 1 1 KAP family P-loop domain AAA_16 PF13191.6 OAP59095.1 - 2.1e-06 28.2 0.0 8.7e-06 26.2 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.22 OAP59095.1 - 0.00029 20.1 0.1 0.00029 20.1 0.1 2.1 2 0 0 2 2 2 1 NB-ARC domain DUF2791 PF10923.8 OAP59095.1 - 0.0024 16.8 0.2 0.0042 16.0 0.2 1.3 1 0 0 1 1 1 1 P-loop Domain of unknown function (DUF2791) ABC_tran PF00005.27 OAP59095.1 - 0.024 15.2 2.4 0.46 11.0 0.0 2.8 2 0 0 2 2 2 0 ABC transporter DUF4211 PF13926.6 OAP59095.1 - 0.058 13.4 0.0 24 5.0 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4211) ATPase_2 PF01637.18 OAP59095.1 - 0.07 13.0 0.2 0.18 11.7 0.2 1.7 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea DUF2071 PF09844.9 OAP59095.1 - 0.074 12.7 0.1 0.18 11.4 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (COG2071) AAA_33 PF13671.6 OAP59095.1 - 0.14 12.3 2.1 0.75 9.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain YebO PF13974.6 OAP59095.1 - 3.8 7.6 12.1 0.25 11.5 4.8 2.8 3 0 0 3 3 3 0 YebO-like protein SKG6 PF08693.10 OAP59097.1 - 0.00081 18.7 1.8 0.0015 17.9 1.8 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain NICE-1 PF15845.5 OAP59097.1 - 0.0065 17.2 0.7 0.0065 17.2 0.7 1.7 1 1 1 2 2 2 1 Cysteine-rich C-terminal 1 family Herpes_gE PF02480.16 OAP59097.1 - 0.015 14.1 0.0 0.022 13.5 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E GPI-anchored PF10342.9 OAP59097.1 - 0.026 15.3 0.2 0.046 14.5 0.2 1.4 1 0 0 1 1 1 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family MLANA PF14991.6 OAP59097.1 - 0.13 12.5 0.0 0.27 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein melan-A AMP-binding PF00501.28 OAP59098.1 - 1.1e-46 159.3 0.0 1.5e-46 158.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 OAP59098.1 - 0.00013 21.8 1.0 0.00018 21.3 0.1 1.8 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 OAP59098.1 - 0.08 13.9 0.0 0.19 12.7 0.0 1.7 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain HET PF06985.11 OAP59099.1 - 4.3e-26 92.0 0.9 6.8e-26 91.4 0.9 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Lyase_1 PF00206.20 OAP59100.1 - 1.2e-91 307.4 0.0 1.9e-91 306.7 0.0 1.3 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 OAP59100.1 - 1.3e-22 80.3 0.2 3.3e-22 79.0 0.2 1.8 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal IL28A PF15177.6 OAP59100.1 - 0.072 12.9 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Interleukin-28A SAPS PF04499.15 OAP59101.1 - 1.8e-195 650.4 0.0 1.8e-195 650.4 0.0 2.1 2 1 0 2 2 2 1 SIT4 phosphatase-associated protein Snf7 PF03357.21 OAP59102.1 - 7.5e-46 155.9 16.1 8.8e-46 155.6 16.1 1.0 1 0 0 1 1 1 1 Snf7 CLZ PF16526.5 OAP59102.1 - 0.001 19.4 4.5 0.042 14.2 0.0 3.4 2 1 1 3 3 3 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF1664 PF07889.12 OAP59102.1 - 0.017 15.1 10.5 0.2 11.7 0.2 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.12 OAP59102.1 - 0.021 15.3 10.1 0.43 11.1 0.2 2.7 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein RE_Bsp6I PF09504.10 OAP59102.1 - 0.042 13.5 0.5 0.086 12.4 0.1 1.7 2 0 0 2 2 2 0 Bsp6I restriction endonuclease HHH_2 PF12826.7 OAP59102.1 - 0.051 13.7 0.0 0.097 12.8 0.0 1.4 1 0 0 1 1 1 0 Helix-hairpin-helix motif DUF4201 PF13870.6 OAP59102.1 - 0.061 13.1 12.1 0.23 11.2 9.4 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) FlaC_arch PF05377.11 OAP59102.1 - 0.11 12.9 8.9 0.63 10.5 0.2 3.5 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) End3 PF12761.7 OAP59102.1 - 0.28 11.3 8.0 0.21 11.7 6.7 1.5 1 1 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 DUF2120 PF09893.9 OAP59102.1 - 0.68 10.0 4.9 0.61 10.2 3.1 1.8 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2120) FapA PF03961.13 OAP59102.1 - 0.69 8.5 12.6 0.4 9.2 4.5 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A DUF2205 PF10224.9 OAP59102.1 - 0.96 9.5 7.8 0.37 10.8 1.2 2.8 1 1 0 2 2 2 0 Short coiled-coil protein Endotoxin_N PF03945.14 OAP59102.1 - 1.1 9.0 7.2 10 5.8 6.8 2.0 1 1 0 1 1 1 0 delta endotoxin, N-terminal domain Muted PF14942.6 OAP59102.1 - 1.7 9.0 11.9 7 7.0 7.1 2.2 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein TRPM_tetra PF16519.5 OAP59102.1 - 2.2 8.5 5.7 23 5.2 1.1 2.9 2 1 1 3 3 3 0 Tetramerisation domain of TRPM DASH_Dam1 PF08653.10 OAP59102.1 - 2.6 7.9 4.9 24 4.8 0.2 3.3 3 0 0 3 3 3 0 DASH complex subunit Dam1 Atg14 PF10186.9 OAP59102.1 - 4.8 6.2 11.2 13 4.8 11.3 1.6 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Sld5 PF05916.11 OAP59103.1 - 6.4e-17 62.0 0.0 8.4e-17 61.6 0.0 1.1 1 0 0 1 1 1 1 GINS complex protein Solute_trans_a PF03619.16 OAP59104.1 - 9.9e-56 189.2 13.3 1.1e-55 189.0 13.3 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Hexapep PF00132.24 OAP59105.1 - 6.5e-12 44.7 7.5 6.7e-07 28.8 2.5 4.2 3 1 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 OAP59105.1 - 0.00017 21.3 3.0 1.7 8.5 0.2 3.8 3 1 1 4 4 4 3 Hexapeptide repeat of succinyl-transferase PAPA-1 PF04795.12 OAP59105.1 - 8.1 7.3 9.8 1.8 9.4 6.5 1.6 2 0 0 2 2 2 0 PAPA-1-like conserved region HET PF06985.11 OAP59106.1 - 6.9e-25 88.1 0.0 1.3e-24 87.3 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Myb_DNA-binding PF00249.31 OAP59108.1 - 0.00041 20.5 0.0 0.0009 19.4 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain KIX_2 PF16987.5 OAP59109.1 - 1.6e-11 44.0 0.0 1.6e-11 44.0 0.0 6.0 6 0 0 6 6 6 1 KIX domain LMBR1 PF04791.16 OAP59110.1 - 2.4e-119 399.5 6.2 2.8e-119 399.3 6.2 1.0 1 0 0 1 1 1 1 LMBR1-like membrane protein Holin_9 PF16936.5 OAP59110.1 - 0.027 14.6 1.4 0.072 13.3 1.4 1.6 1 0 0 1 1 1 0 Putative holin Filament PF00038.21 OAP59110.1 - 0.074 12.6 0.1 2.7 7.5 0.0 2.0 2 0 0 2 2 2 0 Intermediate filament protein SUR7 PF06687.12 OAP59111.1 - 1.1e-22 80.8 11.8 1.4e-22 80.4 11.8 1.1 1 0 0 1 1 1 1 SUR7/PalI family Fungal_trans_2 PF11951.8 OAP59112.1 - 1.3e-08 34.1 0.1 3.9e-08 32.5 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Ion_trans_2 PF07885.16 OAP59113.1 - 3.2e-25 87.9 23.0 9.9e-16 57.5 5.1 3.5 4 0 0 4 4 4 2 Ion channel Arg_decarbox_C PF17944.1 OAP59113.1 - 2.8 8.6 5.1 31 5.2 0.3 2.7 2 0 0 2 2 2 0 Arginine decarboxylase C-terminal helical extension Pyr_redox_2 PF07992.14 OAP59114.1 - 2e-09 37.1 0.0 7.1e-07 28.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 OAP59114.1 - 1.7e-08 33.4 0.1 3.7e-08 32.3 0.0 1.6 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OAP59114.1 - 1.7e-06 28.2 0.0 8.1e-06 26.0 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 OAP59114.1 - 0.062 12.3 0.0 0.31 10.0 0.0 2.0 1 1 0 1 1 1 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 OAP59114.1 - 0.11 12.4 0.6 0.94 9.5 0.0 2.6 3 0 0 3 3 3 0 FAD-NAD(P)-binding Methyltransf_23 PF13489.6 OAP59115.1 - 8.2e-22 77.8 0.0 1.1e-21 77.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAP59115.1 - 1.7e-10 41.5 0.0 3.4e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAP59115.1 - 9.4e-09 35.9 0.0 3.8e-08 34.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAP59115.1 - 2.7e-08 33.7 0.0 4.7e-07 29.7 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAP59115.1 - 2e-06 28.3 0.0 3.5e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 OAP59115.1 - 0.00017 21.1 1.3 0.00021 20.8 0.0 1.8 3 0 0 3 3 3 1 Putative methyltransferase FtsJ PF01728.19 OAP59115.1 - 0.00067 19.8 0.0 0.0011 19.1 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.14 OAP59115.1 - 0.0023 17.5 0.0 0.0039 16.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.18 OAP59115.1 - 0.054 12.8 0.0 0.079 12.2 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain FAD_binding_3 PF01494.19 OAP59116.1 - 2.9e-25 89.2 0.1 6.5e-12 45.4 0.0 3.0 3 0 0 3 3 3 3 FAD binding domain DAO PF01266.24 OAP59116.1 - 8.5e-06 25.6 0.8 0.014 15.0 0.5 2.4 1 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAP59116.1 - 3.2e-05 23.3 0.1 0.033 13.4 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAP59116.1 - 0.0011 19.5 0.4 0.15 12.7 0.1 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAP59116.1 - 0.0012 19.1 0.3 0.0038 17.4 0.3 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 OAP59116.1 - 0.028 13.1 1.3 0.038 12.7 0.1 1.8 3 0 0 3 3 3 0 HI0933-like protein Lycopene_cycl PF05834.12 OAP59116.1 - 0.037 13.1 0.0 0.094 11.8 0.0 1.7 1 1 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 OAP59116.1 - 0.045 13.0 0.0 0.26 10.5 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 OAP59116.1 - 0.051 13.2 0.0 0.13 11.9 0.0 1.7 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.20 OAP59116.1 - 0.074 13.1 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.17 OAP59116.1 - 0.09 12.0 0.2 0.14 11.4 0.2 1.3 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.6 OAP59116.1 - 0.11 12.4 0.2 6.9 6.6 0.0 2.6 3 0 0 3 3 3 0 FAD-NAD(P)-binding DNA_meth_N PF18284.1 OAP59116.1 - 0.15 12.0 0.2 0.32 10.9 0.2 1.4 1 0 0 1 1 1 0 DNA methylase N-terminal domain Lactamase_B PF00753.27 OAP59117.1 - 2.8e-11 43.8 0.5 5.2e-11 42.9 0.5 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OAP59117.1 - 0.0052 16.3 0.2 0.059 12.9 0.1 2.6 2 1 1 3 3 3 1 Beta-lactamase superfamily domain NMO PF03060.15 OAP59118.1 - 1.4e-29 103.6 10.0 6e-22 78.5 8.0 2.3 2 1 0 2 2 2 2 Nitronate monooxygenase IMPDH PF00478.25 OAP59118.1 - 4.2e-06 26.0 0.6 1.1e-05 24.6 0.7 1.6 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 OAP59118.1 - 0.003 16.6 3.8 0.0044 16.1 3.8 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 OAP59118.1 - 0.1 11.7 1.2 0.16 11.1 1.2 1.2 1 0 0 1 1 1 0 Conserved region in glutamate synthase Methyltrn_RNA_3 PF02598.17 OAP59119.1 - 4.6e-112 374.2 0.0 5.5e-112 373.9 0.0 1.1 1 0 0 1 1 1 1 Putative RNA methyltransferase UPF0016 PF01169.19 OAP59120.1 - 7.2e-40 135.2 24.3 1.3e-20 73.5 9.8 2.3 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 Kelch_5 PF13854.6 OAP59122.1 - 5.3e-13 48.6 12.7 8.2e-10 38.5 0.3 5.3 5 0 0 5 5 5 2 Kelch motif Kelch_4 PF13418.6 OAP59122.1 - 1.3e-10 41.1 14.0 6.5e-05 22.9 0.1 6.4 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_6 PF13964.6 OAP59122.1 - 3.2e-10 39.9 7.1 0.27 11.6 0.1 5.1 5 0 0 5 5 5 4 Kelch motif Kelch_3 PF13415.6 OAP59122.1 - 3.6e-05 23.9 14.8 0.028 14.7 0.2 5.8 5 1 0 5 5 5 2 Galactose oxidase, central domain DUF4690 PF15756.5 OAP59122.1 - 0.0004 20.9 0.4 0.0011 19.5 0.4 1.7 1 0 0 1 1 1 1 Small Novel Rich in Cartilage VSP PF03302.13 OAP59122.1 - 0.0017 17.3 0.3 0.0028 16.6 0.3 1.2 1 0 0 1 1 1 1 Giardia variant-specific surface protein Kelch_2 PF07646.15 OAP59122.1 - 0.059 13.4 4.8 27 5.0 0.0 4.2 3 1 0 3 3 3 0 Kelch motif Kelch_1 PF01344.25 OAP59122.1 - 0.067 12.8 0.3 0.067 12.8 0.3 4.8 6 1 0 6 6 6 0 Kelch motif Aa_trans PF01490.18 OAP59123.1 - 1.5e-41 142.4 33.0 1.9e-41 142.2 33.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.6 OAP59123.1 - 0.00015 20.7 52.5 0.01 14.7 51.7 2.1 1 1 0 1 1 1 1 Amino acid permease TPR_2 PF07719.17 OAP59124.1 - 7.3e-32 106.9 11.0 3.8e-06 26.6 0.4 7.7 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_1 PF00515.28 OAP59124.1 - 1.2e-31 107.1 13.6 4.3e-08 32.6 0.6 7.5 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_19 PF14559.6 OAP59124.1 - 1.7e-23 82.9 21.3 4.3e-05 23.9 0.5 6.8 6 1 0 7 7 7 5 Tetratricopeptide repeat TPR_11 PF13414.6 OAP59124.1 - 4.6e-23 80.6 12.7 2.4e-06 27.1 0.1 6.8 4 2 2 6 6 6 5 TPR repeat DnaJ PF00226.31 OAP59124.1 - 5.3e-20 71.3 6.9 7.6e-20 70.8 2.7 2.7 2 0 0 2 2 2 1 DnaJ domain TPR_17 PF13431.6 OAP59124.1 - 3.7e-16 58.3 12.7 0.027 14.9 0.0 6.9 7 0 0 7 7 6 5 Tetratricopeptide repeat TPR_8 PF13181.6 OAP59124.1 - 3.8e-16 57.9 17.0 0.00029 20.8 0.3 7.6 8 0 0 8 8 6 5 Tetratricopeptide repeat TPR_7 PF13176.6 OAP59124.1 - 1.1e-14 53.3 10.4 0.019 14.9 0.2 7.5 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.6 OAP59124.1 - 5.2e-14 52.6 16.2 0.0019 18.8 0.0 6.0 6 1 1 7 7 5 4 Tetratricopeptide repeat TPR_14 PF13428.6 OAP59124.1 - 6e-14 51.6 10.3 0.052 14.4 0.2 7.4 3 2 4 7 7 7 3 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 OAP59124.1 - 5.4e-10 39.2 4.8 0.00018 21.5 0.1 4.9 4 2 1 5 5 5 2 Fis1 C-terminal tetratricopeptide repeat TPR_9 PF13371.6 OAP59124.1 - 9.6e-10 38.5 4.5 2.8e-06 27.4 0.2 4.0 4 1 1 5 5 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 OAP59124.1 - 2.5e-08 34.0 4.6 7.8e-05 22.8 0.2 3.8 2 1 3 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 BTAD PF03704.17 OAP59124.1 - 3.1e-08 34.2 4.1 0.018 15.4 0.1 4.6 2 2 3 5 5 5 2 Bacterial transcriptional activator domain TPR_12 PF13424.6 OAP59124.1 - 6.4e-08 32.8 15.3 0.23 11.8 0.6 6.4 5 2 1 6 6 5 3 Tetratricopeptide repeat TPR_6 PF13174.6 OAP59124.1 - 5.8e-07 29.7 17.2 3.9 8.3 0.2 8.2 7 1 1 8 8 8 2 Tetratricopeptide repeat TPR_10 PF13374.6 OAP59124.1 - 1.2e-05 25.1 13.4 1 9.3 0.0 7.2 7 0 0 7 7 7 2 Tetratricopeptide repeat TOM20_plant PF06552.12 OAP59124.1 - 0.00018 21.3 9.2 0.072 12.8 0.1 4.1 3 2 2 5 5 5 2 Plant specific mitochondrial import receptor subunit TOM20 ChAPs PF09295.10 OAP59124.1 - 0.012 14.7 0.6 0.32 9.9 0.1 2.2 2 0 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) RPT PF13446.6 OAP59124.1 - 0.047 13.6 2.6 0.39 10.7 0.0 3.6 4 0 0 4 4 3 0 A repeated domain in UCH-protein Coatomer_E PF04733.14 OAP59124.1 - 0.091 12.2 3.9 0.59 9.5 0.5 2.7 2 1 1 3 3 3 0 Coatomer epsilon subunit MIT PF04212.18 OAP59124.1 - 0.15 12.2 5.4 24 5.1 0.1 4.6 4 1 0 4 4 4 0 MIT (microtubule interacting and transport) domain TPM_phosphatase PF04536.14 OAP59124.1 - 0.33 11.1 2.1 22 5.3 0.1 3.0 3 0 0 3 3 2 0 TPM domain SHNi-TPR PF10516.9 OAP59124.1 - 2 7.9 7.8 9.7 5.7 0.0 4.7 6 0 0 6 6 5 0 SHNi-TPR MAGE PF01454.19 OAP59125.1 - 8.4e-56 189.0 0.0 1.7e-55 188.0 0.0 1.5 1 0 0 1 1 1 1 MAGE family IBR PF01485.21 OAP59126.1 - 4.8e-07 29.9 28.9 0.00023 21.3 6.3 4.5 3 1 0 4 4 4 4 IBR domain, a half RING-finger domain FYVE PF01363.21 OAP59126.1 - 0.15 12.3 35.9 1.1 9.4 1.2 3.8 4 0 0 4 4 4 0 FYVE zinc finger ABC2_membrane PF01061.24 OAP59127.1 - 5e-29 101.2 27.1 8.9e-29 100.4 27.1 1.4 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 OAP59127.1 - 5.4e-25 88.5 0.2 8.1e-25 87.9 0.2 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 OAP59127.1 - 7.2e-07 28.9 0.2 1.2e-06 28.2 0.2 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain ABC2_membrane_3 PF12698.7 OAP59127.1 - 4.4e-06 26.1 4.7 4.4e-06 26.1 4.7 2.2 1 1 0 2 2 2 1 ABC-2 family transporter protein AAA_21 PF13304.6 OAP59127.1 - 2.2e-05 24.5 0.2 0.074 12.8 0.0 2.3 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 OAP59127.1 - 2.3e-05 24.4 0.6 0.00032 20.6 0.4 2.1 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 OAP59127.1 - 0.00013 22.4 0.1 0.00022 21.6 0.1 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OAP59127.1 - 0.0012 19.1 0.1 0.0043 17.3 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 OAP59127.1 - 0.0017 18.0 0.1 0.004 16.8 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_13 PF13166.6 OAP59127.1 - 0.003 16.3 0.1 0.069 11.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.22 OAP59127.1 - 0.0053 16.4 0.1 0.012 15.3 0.1 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_28 PF13521.6 OAP59127.1 - 0.0084 16.4 0.0 0.014 15.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 OAP59127.1 - 0.0093 16.4 0.2 0.037 14.4 0.2 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 OAP59127.1 - 0.0097 16.5 0.0 0.019 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain Phosphoprotein PF00922.17 OAP59127.1 - 0.015 14.9 0.1 0.027 14.1 0.1 1.3 1 0 0 1 1 1 0 Vesiculovirus phosphoprotein AAA_29 PF13555.6 OAP59127.1 - 0.016 15.0 0.2 0.036 13.8 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain SbcCD_C PF13558.6 OAP59127.1 - 0.024 14.8 0.1 0.087 13.1 0.1 1.9 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit NB-ARC PF00931.22 OAP59127.1 - 0.03 13.5 0.1 0.049 12.8 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain cobW PF02492.19 OAP59127.1 - 0.039 13.5 0.1 0.067 12.8 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Rad17 PF03215.15 OAP59127.1 - 0.045 13.7 0.0 0.075 12.9 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_30 PF13604.6 OAP59127.1 - 0.058 13.1 0.1 0.11 12.3 0.1 1.4 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 OAP59127.1 - 0.068 12.2 0.2 0.11 11.5 0.2 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_33 PF13671.6 OAP59127.1 - 0.075 13.2 0.2 0.16 12.1 0.2 1.7 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 OAP59127.1 - 0.08 12.9 0.1 0.15 11.9 0.1 1.4 1 0 0 1 1 1 0 NACHT domain AAA_5 PF07728.14 OAP59127.1 - 0.085 12.9 0.0 0.3 11.1 0.1 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.23 OAP59127.1 - 0.13 12.3 0.1 0.29 11.2 0.1 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_24 PF13479.6 OAP59127.1 - 0.16 11.7 0.0 0.36 10.5 0.0 1.6 2 0 0 2 2 1 0 AAA domain ATPase_2 PF01637.18 OAP59127.1 - 0.2 11.6 0.0 0.33 10.8 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Zn_clus PF00172.18 OAP59128.1 - 1.8e-09 37.6 7.5 3.3e-09 36.7 7.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAP59128.1 - 9.3e-09 34.7 0.0 1.4e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain CaKB PF03185.15 OAP59130.1 - 0.04 13.6 2.6 0.04 13.6 2.6 1.7 1 1 0 1 1 1 0 Calcium-activated potassium channel, beta subunit HSCB_C PF07743.13 OAP59130.1 - 0.22 12.1 0.0 0.69 10.4 0.0 1.8 1 1 0 1 1 1 0 HSCB C-terminal oligomerisation domain GST_N PF02798.20 OAP59131.1 - 5.3e-14 52.3 0.0 9.2e-14 51.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OAP59131.1 - 8.5e-12 45.1 0.0 1.2e-11 44.7 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 OAP59131.1 - 4.7e-11 42.9 0.0 1.2e-10 41.7 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OAP59131.1 - 1.9e-09 37.7 0.0 4.3e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAP59131.1 - 1.1e-06 28.6 0.0 1.9e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OAP59131.1 - 3.1e-05 24.1 0.0 5.1e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Sugar_tr PF00083.24 OAP59132.1 - 7.1e-104 348.2 20.0 8.1e-104 348.0 20.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP59132.1 - 4.1e-24 85.2 34.1 1.4e-18 67.0 17.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily VEGFR-2_TMD PF17988.1 OAP59132.1 - 0.029 13.8 0.7 0.087 12.3 0.7 1.9 1 0 0 1 1 1 0 VEGFR-2 Transmembrane domain MatC_N PF07158.11 OAP59132.1 - 0.1 12.6 5.3 0.061 13.3 2.4 2.0 2 0 0 2 2 2 0 Dicarboxylate carrier protein MatC N-terminus Lig_chan PF00060.26 OAP59132.1 - 0.33 10.8 2.8 1.2 9.0 0.1 2.6 2 0 0 2 2 2 0 Ligand-gated ion channel Alpha-L-AF_C PF06964.12 OAP59133.1 - 2e-28 99.7 0.0 2.8e-28 99.1 0.0 1.2 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain Fungal_trans PF04082.18 OAP59134.1 - 2.7e-14 52.9 0.0 6.6e-14 51.6 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain COPI_assoc PF08507.10 OAP59135.1 - 1.8 8.6 5.0 3.7 7.6 0.0 2.9 3 0 0 3 3 3 0 COPI associated protein CFEM PF05730.11 OAP59136.1 - 6.9e-14 51.7 11.7 9.8e-14 51.2 11.7 1.2 1 0 0 1 1 1 1 CFEM domain DUF1422 PF07226.11 OAP59136.1 - 0.088 12.8 0.2 0.26 11.3 0.0 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1422) DUF2516 PF10724.9 OAP59136.1 - 0.26 11.6 0.2 0.26 11.6 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2516) MSP1_C PF07462.11 OAP59136.1 - 9 4.9 4.5 11 4.6 4.5 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus dCMP_cyt_deam_1 PF00383.23 OAP59137.1 - 2.9e-09 36.7 0.0 4.1e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 OAP59137.1 - 2e-06 27.6 0.0 3e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 MafB19-like deaminase Glyoxalase PF00903.25 OAP59138.1 - 0.006 16.8 0.0 0.0074 16.5 0.0 1.3 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily SIMPL PF04402.14 OAP59139.1 - 1.5e-21 77.8 0.5 1.7e-21 77.6 0.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF541) DAO PF01266.24 OAP59140.1 - 1e-44 153.6 0.2 1.3e-44 153.3 0.2 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAP59140.1 - 0.00012 22.3 0.1 0.0003 21.0 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 OAP59140.1 - 0.003 16.8 0.0 0.0048 16.2 0.0 1.2 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 OAP59140.1 - 0.0031 17.5 0.1 1.6 8.7 0.1 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 OAP59140.1 - 0.011 14.9 0.1 0.08 12.0 0.1 2.0 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_2 PF07992.14 OAP59140.1 - 0.011 15.0 0.0 0.024 13.9 0.0 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAP59140.1 - 0.022 14.0 0.0 0.58 9.4 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAP59140.1 - 0.15 10.8 0.0 6.2 5.4 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein DUF3074 PF11274.8 OAP59141.1 - 4.2e-59 199.6 3.0 6.3e-59 199.0 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3074) DUF4407 PF14362.6 OAP59141.1 - 6.3 6.1 21.2 12 5.1 21.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Exonuc_VII_L PF02601.15 OAP59141.1 - 6.8 6.2 16.0 13 5.3 16.0 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit Ubiquitin_3 PF14836.6 OAP59142.1 - 0.059 13.4 0.3 0.13 12.3 0.3 1.5 1 0 0 1 1 1 0 Ubiquitin-like domain NAD_binding_1 PF00175.21 OAP59143.1 - 7.9e-28 97.3 0.1 1.9e-27 96.0 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 OAP59143.1 - 1.7e-15 57.1 0.0 8.2e-15 55.0 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 OAP59143.1 - 1.1e-05 25.6 0.0 0.00065 19.9 0.0 2.4 1 1 1 2 2 2 1 Ferric reductase NAD binding domain NT-C2 PF10358.9 OAP59144.1 - 1.7e-34 118.6 0.0 2.5e-34 118.1 0.0 1.3 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins DUF4834 PF16118.5 OAP59144.1 - 3.3 8.7 5.1 1.4 10.0 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) SLS PF14611.6 OAP59146.1 - 1.6e-09 37.9 0.0 3.2e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator Spc42p PF11544.8 OAP59146.1 - 0.13 12.3 0.3 0.39 10.8 0.3 1.8 1 0 0 1 1 1 0 Spindle pole body component Spc42p Sugar_tr PF00083.24 OAP59147.1 - 2.1e-69 234.6 18.6 2.4e-69 234.3 18.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP59147.1 - 4e-15 55.6 24.6 4e-15 55.6 24.6 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 OAP59147.1 - 0.071 11.9 17.2 0.26 10.1 4.3 2.4 2 0 0 2 2 2 0 MFS_1 like family Sugar_tr PF00083.24 OAP59148.1 - 3.6e-72 243.7 22.1 4.2e-72 243.4 22.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP59148.1 - 3.6e-15 55.8 33.8 3.6e-15 55.8 33.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 OAP59148.1 - 3.1e-06 26.7 2.8 3.1e-06 26.7 2.8 2.0 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB MFS_3 PF05977.13 OAP59148.1 - 0.0013 17.2 1.9 0.0013 17.2 1.9 2.0 2 0 0 2 2 2 1 Transmembrane secretion effector MFS_5 PF05631.14 OAP59148.1 - 0.003 16.6 0.4 0.003 16.6 0.4 2.0 2 0 0 2 2 2 1 Sugar-tranasporters, 12 TM MFS_1_like PF12832.7 OAP59148.1 - 0.085 11.7 20.9 0.029 13.3 4.9 2.4 2 0 0 2 2 2 0 MFS_1 like family Melibiase_2 PF16499.5 OAP59149.1 - 4.6e-55 186.8 9.3 1.3e-53 182.1 9.3 2.2 1 1 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 OAP59149.1 - 1.3e-09 38.0 0.1 4.2e-08 33.1 0.0 2.5 2 0 0 2 2 2 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 OAP59149.1 - 3e-05 23.1 0.4 5.3e-05 22.3 0.0 1.5 2 0 0 2 2 2 1 Melibiase Fungal_trans PF04082.18 OAP59150.1 - 3.8e-07 29.4 0.1 1e-06 28.0 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain MFS_1 PF07690.16 OAP59151.1 - 6.4e-17 61.5 40.4 4.2e-12 45.7 17.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily HpcH_HpaI PF03328.14 OAP59153.1 - 1.9e-38 131.8 0.0 2.5e-38 131.4 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family Fungal_trans PF04082.18 OAP59154.1 - 5.4e-17 61.7 0.0 8.5e-17 61.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP59154.1 - 0.00029 20.9 9.5 0.00052 20.1 9.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ABC_tran PF00005.27 OAP59155.1 - 8.9e-38 129.9 1.6 2.4e-20 73.4 0.0 3.5 3 1 0 3 3 2 2 ABC transporter AAA_21 PF13304.6 OAP59155.1 - 1.5e-12 48.0 9.2 0.011 15.5 0.1 4.3 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OAP59155.1 - 3e-12 46.5 0.5 0.00013 21.4 0.1 4.2 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain ABC_tran_Xtn PF12848.7 OAP59155.1 - 1e-09 38.3 6.4 1e-09 38.3 6.4 2.3 2 0 0 2 2 1 1 ABC transporter Metallophos PF00149.28 OAP59155.1 - 1.2e-09 39.0 2.0 2.2e-09 38.2 2.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase AAA_29 PF13555.6 OAP59155.1 - 1.8e-06 27.6 0.1 0.1 12.3 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_28 PF13521.6 OAP59155.1 - 3.4e-05 24.2 3.8 8.1e-05 22.9 0.4 2.8 2 1 0 2 2 2 1 AAA domain AAA_23 PF13476.6 OAP59155.1 - 0.00011 22.8 10.1 0.057 13.9 0.0 4.0 4 0 0 4 4 4 2 AAA domain MMR_HSR1 PF01926.23 OAP59155.1 - 0.00016 21.7 0.7 0.62 10.2 0.0 3.1 3 0 0 3 3 2 2 50S ribosome-binding GTPase AAA_18 PF13238.6 OAP59155.1 - 0.00018 22.1 0.2 0.97 10.0 0.0 2.9 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 OAP59155.1 - 0.00095 19.1 1.2 0.46 10.4 0.0 3.1 3 0 0 3 3 3 1 RsgA GTPase AAA_16 PF13191.6 OAP59155.1 - 0.0013 19.1 7.5 0.35 11.3 0.1 2.9 2 1 0 2 2 2 2 AAA ATPase domain AAA_5 PF07728.14 OAP59155.1 - 0.0018 18.3 1.2 3.9 7.5 0.0 3.7 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) DUF815 PF05673.13 OAP59155.1 - 0.002 17.4 1.2 0.11 11.7 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_33 PF13671.6 OAP59155.1 - 0.0021 18.3 3.2 0.85 9.8 0.1 3.0 3 0 0 3 3 3 2 AAA domain AAA PF00004.29 OAP59155.1 - 0.0026 18.2 0.9 3.5 8.1 0.0 3.8 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 OAP59155.1 - 0.0037 17.2 0.2 4.9 7.1 0.1 3.0 3 0 0 3 3 3 2 NACHT domain AAA_25 PF13481.6 OAP59155.1 - 0.0059 16.2 1.1 7.4 6.1 1.4 3.1 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.6 OAP59155.1 - 0.011 16.1 3.5 0.69 10.2 0.0 3.3 3 1 0 3 3 3 0 AAA domain FtsK_SpoIIIE PF01580.18 OAP59155.1 - 0.014 14.7 0.1 2.7 7.3 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family Luteo_coat PF00894.18 OAP59155.1 - 0.073 13.0 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 Luteovirus coat protein AAA_13 PF13166.6 OAP59155.1 - 0.089 11.4 4.9 3.9 6.0 0.0 3.4 3 0 0 3 3 3 0 AAA domain SbcCD_C PF13558.6 OAP59155.1 - 0.095 13.0 0.2 0.53 10.6 0.0 2.5 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.6 OAP59155.1 - 0.11 12.1 1.6 2 8.0 0.0 2.8 3 0 0 3 3 3 0 AAA ATPase domain RNA_helicase PF00910.22 OAP59155.1 - 0.13 12.7 0.1 28 5.2 0.1 2.7 2 0 0 2 2 2 0 RNA helicase DUF5615 PF18480.1 OAP59155.1 - 0.18 11.6 0.4 5.4 6.8 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF5615) ING PF12998.7 OAP59157.1 - 5.1e-05 23.8 0.0 0.00012 22.7 0.0 1.7 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding Ras PF00071.22 OAP59158.1 - 1.2e-55 187.5 0.0 1.9e-55 186.9 0.0 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAP59158.1 - 1.2e-33 115.9 0.0 2.1e-33 115.1 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAP59158.1 - 3.1e-13 49.5 0.0 9.2e-13 48.0 0.0 1.6 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OAP59158.1 - 7.9e-06 25.5 0.0 1.3e-05 24.9 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OAP59158.1 - 0.00011 21.6 0.0 0.00018 21.0 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OAP59158.1 - 0.00018 21.5 0.0 0.00035 20.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OAP59158.1 - 0.031 14.2 0.1 2.6 7.9 0.0 2.6 2 1 0 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 OAP59158.1 - 0.047 14.1 1.1 0.12 12.8 1.1 2.0 1 1 0 1 1 1 0 AAA ATPase domain EI24 PF07264.11 OAP59159.1 - 8.7e-14 52.2 0.8 1.4e-13 51.4 0.8 1.3 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) OFeT_1 PF16955.5 OAP59159.1 - 0.044 13.5 1.7 0.072 12.8 0.0 1.9 2 0 0 2 2 2 0 Ferrous iron uptake permease, iron-lead transporter SoPB_HTH PF18090.1 OAP59159.1 - 0.15 12.2 0.0 0.3 11.3 0.0 1.5 1 0 0 1 1 1 0 Centromere-binding protein HTH domain DUF4185 PF13810.6 OAP59160.1 - 8.7e-06 25.2 0.0 2.8e-05 23.5 0.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4185) PAN_4 PF14295.6 OAP59160.1 - 0.027 14.4 0.2 0.084 12.8 0.2 1.9 1 1 0 1 1 1 0 PAN domain Fungal_trans_2 PF11951.8 OAP59162.1 - 0.0007 18.5 0.0 0.0011 17.9 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.25 OAP59163.1 - 3.9e-31 108.0 0.0 5.3e-31 107.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP59163.1 - 2.6e-24 86.1 0.0 3.4e-24 85.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP59163.1 - 1.2e-08 35.1 2.0 1.2e-08 35.1 0.7 1.5 2 0 0 2 2 2 1 KR domain Shikimate_DH PF01488.20 OAP59163.1 - 0.033 14.3 0.1 0.072 13.1 0.0 1.5 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.15 OAP59163.1 - 0.072 12.2 0.0 0.41 9.7 0.0 1.9 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein F420H2_quin_red PF04075.14 OAP59163.1 - 0.11 12.7 0.1 0.16 12.1 0.1 1.3 1 0 0 1 1 1 0 F420H(2)-dependent quinone reductase MmgE_PrpD PF03972.14 OAP59164.1 - 1.4e-112 376.4 0.2 1.7e-112 376.2 0.2 1.0 1 0 0 1 1 1 1 MmgE/PrpD family MFS_1 PF07690.16 OAP59165.1 - 1.1e-43 149.6 28.4 1.6e-40 139.1 13.5 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAP59165.1 - 1.5e-16 60.3 7.3 1.5e-16 60.3 7.3 2.5 3 0 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 OAP59165.1 - 4.6e-05 22.0 3.0 4.6e-05 22.0 3.0 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 OAP59165.1 - 0.71 8.7 8.8 0.24 10.2 0.1 2.9 2 1 1 3 3 3 0 MFS_1 like family ANAPC4_WD40 PF12894.7 OAP59166.1 - 1.2e-09 38.4 0.2 0.022 15.0 0.0 6.0 5 2 2 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OAP59166.1 - 4.5e-07 30.5 1.3 0.11 13.4 0.1 5.8 6 0 0 6 6 5 1 WD domain, G-beta repeat PGAP1 PF07819.13 OAP59166.1 - 3.6e-05 23.6 0.0 0.00013 21.8 0.0 1.9 2 0 0 2 2 2 1 PGAP1-like protein DUF676 PF05057.14 OAP59166.1 - 0.0008 19.0 0.0 0.0023 17.5 0.0 1.7 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_2 PF01674.18 OAP59166.1 - 0.0011 18.5 0.3 0.021 14.4 0.0 2.5 3 0 0 3 3 3 1 Lipase (class 2) Abhydrolase_6 PF12697.7 OAP59166.1 - 0.0028 18.3 0.5 0.0093 16.6 0.1 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family LCAT PF02450.15 OAP59166.1 - 0.021 14.0 0.0 0.042 13.0 0.0 1.4 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase 6PF2K PF01591.18 OAP59166.1 - 0.035 13.4 0.0 0.078 12.3 0.0 1.5 1 0 0 1 1 1 0 6-phosphofructo-2-kinase DUF2004 PF09406.10 OAP59166.1 - 0.041 14.2 0.0 0.13 12.6 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2004) DUF829 PF05705.14 OAP59166.1 - 0.08 12.8 0.0 0.5 10.2 0.0 2.1 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF829) TFIIIC_delta PF12657.7 OAP59166.1 - 0.081 12.9 0.0 4.4 7.2 0.0 2.6 2 0 0 2 2 2 0 Transcription factor IIIC subunit delta N-term Hydrolase_4 PF12146.8 OAP59166.1 - 0.093 12.0 0.1 0.51 9.6 0.0 2.1 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Fructosamin_kin PF03881.14 OAP59167.1 - 3.4e-36 124.9 0.1 4.5e-36 124.5 0.1 1.1 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 OAP59167.1 - 0.00022 21.2 0.0 0.00034 20.6 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Aconitase PF00330.20 OAP59168.1 - 6.2e-69 233.2 0.0 4.6e-67 227.0 0.0 2.1 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 OAP59168.1 - 1.2e-12 48.3 0.0 2.3e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain PEP_mutase PF13714.6 OAP59169.1 - 7.3e-43 146.7 0.1 9e-43 146.4 0.1 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 OAP59169.1 - 1.1e-18 67.0 0.2 1.5e-18 66.6 0.2 1.1 1 0 0 1 1 1 1 Isocitrate lyase family Fungal_trans PF04082.18 OAP59171.1 - 4.9e-21 74.9 0.1 1.1e-20 73.9 0.1 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain RRM_1 PF00076.22 OAP59172.1 - 0.0015 18.3 0.0 0.0027 17.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) QueT PF06177.11 OAP59173.1 - 0.019 15.4 0.4 0.036 14.4 0.4 1.4 1 0 0 1 1 1 0 QueT transporter Ank_2 PF12796.7 OAP59174.1 - 0.03 14.9 0.0 0.11 13.2 0.0 1.8 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OAP59174.1 - 0.03 14.6 0.1 1.9 8.9 0.0 3.1 2 1 1 3 3 3 0 Ankyrin repeats (many copies) CorA PF01544.18 OAP59175.1 - 0.00012 21.5 5.5 0.00022 20.7 5.5 1.5 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein SecE PF00584.20 OAP59176.1 - 7.7e-07 29.0 1.8 5.9e-05 22.9 0.0 2.7 3 0 0 3 3 3 2 SecE/Sec61-gamma subunits of protein translocation complex Ripply PF14998.6 OAP59176.1 - 0.015 15.9 0.1 0.083 13.5 0.0 1.9 2 0 0 2 2 2 0 Transcription Regulator WD40 PF00400.32 OAP59177.1 - 1.6e-21 76.2 20.4 0.00045 21.0 0.3 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat Kelch_6 PF13964.6 OAP59177.1 - 0.0097 16.2 0.7 0.59 10.5 0.0 3.5 3 0 0 3 3 3 1 Kelch motif ANAPC4_WD40 PF12894.7 OAP59177.1 - 0.036 14.4 0.0 0.7 10.2 0.0 2.9 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 OAP59177.1 - 0.065 13.2 0.1 0.47 10.5 0.0 2.5 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat PQQ_3 PF13570.6 OAP59177.1 - 0.071 13.6 0.4 77 4.0 0.1 3.9 3 0 0 3 3 3 0 PQQ-like domain Cytochrom_D1 PF02239.16 OAP59177.1 - 0.096 11.2 0.8 0.63 8.5 0.0 2.5 3 0 0 3 3 3 0 Cytochrome D1 heme domain SDA1 PF05285.12 OAP59177.1 - 9.1 5.6 8.9 14 5.0 8.9 1.2 1 0 0 1 1 1 0 SDA1 Spt20 PF12090.8 OAP59178.1 - 2.6 7.6 9.8 3.5 7.2 9.8 1.2 1 0 0 1 1 1 0 Spt20 family SUIM_assoc PF16619.5 OAP59178.1 - 5.2 7.2 16.7 1.1 9.4 12.3 2.1 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 TonB_C PF03544.14 OAP59179.1 - 0.041 14.3 0.0 0.095 13.2 0.0 1.5 1 0 0 1 1 1 0 Gram-negative bacterial TonB protein C-terminal Vpu PF00558.19 OAP59181.1 - 0.063 13.1 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Vpu protein Sec39 PF08314.11 OAP59182.1 - 4.7e-188 627.1 3.6 5.5e-188 626.9 3.6 1.0 1 0 0 1 1 1 1 Secretory pathway protein Sec39 Ndufs5 PF10200.9 OAP59183.1 - 4.2e-05 23.7 0.0 5.6e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa DUF3128 PF11326.8 OAP59183.1 - 0.00075 19.8 0.9 0.0022 18.3 0.9 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3128) UPF0203 PF05254.12 OAP59183.1 - 0.38 11.0 3.5 1.5 9.1 3.6 1.8 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) DUF3535 PF12054.8 OAP59184.1 - 4.3e-115 385.4 1.2 1.9e-114 383.3 0.5 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF3535) SNF2_N PF00176.23 OAP59184.1 - 1.6e-64 217.9 0.0 1.2e-63 215.0 0.0 2.2 2 1 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OAP59184.1 - 4.2e-20 72.1 0.0 1.1e-19 70.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT PF02985.22 OAP59184.1 - 2.2e-15 55.4 3.2 0.015 15.5 0.0 8.1 7 0 0 7 7 7 5 HEAT repeat HEAT_2 PF13646.6 OAP59184.1 - 1.5e-06 28.5 1.6 0.011 16.1 0.1 5.3 6 0 0 6 6 6 1 HEAT repeats Adaptin_N PF01602.20 OAP59184.1 - 0.011 14.4 3.0 8.7 4.8 0.0 3.8 4 0 0 4 4 4 0 Adaptin N terminal region TAF6_C PF07571.13 OAP59184.1 - 0.021 15.1 0.1 17 5.8 0.0 4.7 5 0 0 5 5 5 0 TAF6 C-terminal HEAT repeat domain Vac14_Fab1_bd PF12755.7 OAP59184.1 - 0.024 15.2 0.0 18 6.0 0.0 3.8 3 1 0 4 4 4 0 Vacuolar 14 Fab1-binding region ERCC3_RAD25_C PF16203.5 OAP59184.1 - 0.064 12.5 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase HEAT_EZ PF13513.6 OAP59184.1 - 1.9 9.1 6.8 15 6.2 0.1 5.5 7 0 0 7 7 7 0 HEAT-like repeat Cupin_1 PF00190.22 OAP59185.1 - 3.8e-18 65.6 0.6 5.4e-18 65.0 0.6 1.2 1 0 0 1 1 1 1 Cupin MAPEG PF01124.18 OAP59186.1 - 5.5e-19 68.4 0.1 7.5e-19 67.9 0.1 1.2 1 0 0 1 1 1 1 MAPEG family DUF1180 PF06679.12 OAP59186.1 - 0.025 15.0 0.1 0.029 14.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) APH PF01636.23 OAP59187.1 - 1.8e-13 50.9 0.0 2.8e-13 50.3 0.0 1.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 OAP59187.1 - 3.8e-06 26.4 0.4 1.2e-05 24.8 0.2 1.8 2 0 0 2 2 2 1 Ecdysteroid kinase DUF1679 PF07914.11 OAP59187.1 - 0.00018 20.5 0.1 0.027 13.3 0.1 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF1679) Choline_kinase PF01633.20 OAP59187.1 - 0.0027 17.3 0.1 0.0051 16.4 0.1 1.4 2 0 0 2 2 2 1 Choline/ethanolamine kinase Exo_endo_phos PF03372.23 OAP59190.1 - 3.8e-07 29.9 0.6 5.3e-07 29.4 0.6 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 OAP59190.1 - 0.028 14.3 0.4 0.15 11.9 0.4 2.0 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase Gln-synt_C PF00120.24 OAP59191.1 - 1e-60 205.6 0.0 2.1e-60 204.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Amidohydro_2 PF04909.14 OAP59191.1 - 3e-16 60.1 0.5 6.7e-15 55.6 0.0 2.3 2 0 0 2 2 2 1 Amidohydrolase Aldedh PF00171.22 OAP59192.1 - 1e-148 495.7 0.1 1.3e-148 495.4 0.1 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family GPI2 PF06432.11 OAP59193.1 - 2.8e-122 407.5 0.4 3.4e-122 407.3 0.4 1.1 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase adh_short PF00106.25 OAP59194.1 - 1.7e-22 79.9 0.5 2.8e-22 79.1 0.5 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP59194.1 - 6.9e-14 52.0 0.4 6.9e-14 52.0 0.4 1.8 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP59194.1 - 0.00031 20.7 0.0 0.00077 19.4 0.0 1.6 1 0 0 1 1 1 1 KR domain Zn_clus PF00172.18 OAP59194.1 - 0.0034 17.5 4.8 0.0063 16.6 4.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Epimerase PF01370.21 OAP59194.1 - 0.051 13.0 0.2 0.14 11.6 0.2 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Sugar_tr PF00083.24 OAP59195.1 - 3.4e-82 276.7 17.0 3.8e-82 276.5 17.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP59195.1 - 8.5e-26 90.7 32.8 5.4e-25 88.1 23.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 OAP59197.1 - 3.3e-45 154.5 21.3 3.3e-45 154.5 21.3 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAP59197.1 - 1.4e-07 30.8 3.6 1.4e-07 30.8 3.6 2.0 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 OAP59197.1 - 0.0058 15.1 1.2 0.01 14.3 1.2 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) FPN1 PF06963.12 OAP59197.1 - 0.011 14.4 0.0 0.011 14.4 0.0 1.8 3 0 0 3 3 3 0 Ferroportin1 (FPN1) LMBR1 PF04791.16 OAP59198.1 - 0.0038 16.2 0.4 0.0052 15.8 0.4 1.3 1 0 0 1 1 1 1 LMBR1-like membrane protein V_ATPase_I PF01496.19 OAP59198.1 - 3.8 5.3 29.2 5.3 4.8 29.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Macoilin PF09726.9 OAP59198.1 - 9.6 4.6 34.2 15 4.0 34.2 1.2 1 0 0 1 1 1 0 Macoilin family Fungal_trans PF04082.18 OAP59199.1 - 7.3e-13 48.1 0.1 1.4e-12 47.3 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain APH PF01636.23 OAP59199.1 - 6.2e-05 23.0 0.3 0.00018 21.5 0.3 1.8 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 OAP59199.1 - 0.0076 15.9 0.1 0.015 14.9 0.1 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pyr_redox_2 PF07992.14 OAP59200.1 - 3.6e-15 56.0 0.0 1.3e-13 50.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAP59200.1 - 7e-15 55.1 0.0 4.3e-13 49.2 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 OAP59200.1 - 2.2e-08 33.0 0.1 5.2e-07 28.5 0.1 2.3 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 OAP59200.1 - 2.4e-08 33.5 0.3 1.1e-06 28.0 0.1 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 OAP59200.1 - 3.5e-07 30.3 0.0 1.1e-05 25.6 0.0 2.9 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 OAP59200.1 - 7e-05 23.3 0.9 0.54 10.8 0.1 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 OAP59200.1 - 7.8e-05 22.1 0.1 0.0022 17.3 0.1 2.6 3 0 0 3 3 3 1 FAD binding domain DAO PF01266.24 OAP59200.1 - 0.0029 17.3 0.0 0.44 10.1 0.0 2.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OAP59200.1 - 0.0038 16.4 0.7 0.012 14.7 0.2 2.0 3 0 0 3 3 3 1 FAD binding domain 3HCDH_N PF02737.18 OAP59200.1 - 0.008 16.1 0.3 2.7 7.8 0.0 2.3 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 OAP59200.1 - 0.0083 15.5 0.2 0.035 13.5 0.0 1.9 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HI0933_like PF03486.14 OAP59200.1 - 0.058 12.1 0.1 0.13 10.9 0.0 1.6 2 0 0 2 2 2 0 HI0933-like protein XdhC_C PF13478.6 OAP59200.1 - 0.1 13.1 0.1 1.2 9.7 0.0 2.3 2 0 0 2 2 2 0 XdhC Rossmann domain Lycopene_cycl PF05834.12 OAP59200.1 - 0.11 11.5 0.0 0.25 10.4 0.0 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein TrkA_N PF02254.18 OAP59200.1 - 0.14 12.5 0.0 0.35 11.2 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain Shikimate_DH PF01488.20 OAP59200.1 - 0.17 12.0 0.0 20 5.2 0.0 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase adh_short PF00106.25 OAP59201.1 - 8.9e-31 106.9 0.0 3.3e-30 105.0 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP59201.1 - 3.4e-20 72.6 0.0 1.8e-19 70.3 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Sugar_tr PF00083.24 OAP59202.1 - 3.3e-72 243.8 28.1 3.7e-72 243.6 28.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP59202.1 - 2.7e-20 72.6 38.9 4e-10 39.1 16.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily adh_short_C2 PF13561.6 OAP59203.1 - 2.1e-61 207.4 0.2 3.1e-61 206.9 0.2 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP59203.1 - 4.2e-47 160.1 0.2 6.9e-47 159.4 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAP59203.1 - 4.4e-08 33.3 0.8 1.4e-07 31.6 0.8 1.8 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OAP59203.1 - 0.025 13.7 0.0 0.041 13.0 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Methyltransf_25 PF13649.6 OAP59203.1 - 0.085 13.6 0.1 0.18 12.6 0.1 1.6 1 0 0 1 1 1 0 Methyltransferase domain Lactamase_B PF00753.27 OAP59204.1 - 1e-09 38.7 0.1 1.6e-09 38.1 0.1 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OAP59204.1 - 0.00042 19.9 0.0 0.00099 18.7 0.0 1.7 1 0 0 1 1 1 1 Beta-lactamase superfamily domain PT-VENN PF04829.13 OAP59205.1 - 2.3 8.4 6.6 2.2 8.4 4.0 2.3 2 0 0 2 2 2 0 Pre-toxin domain with VENN motif adh_short PF00106.25 OAP59206.1 - 3.1e-18 66.0 0.1 1.5e-17 63.7 0.1 2.1 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 OAP59206.1 - 5.6e-11 42.7 0.1 8.5e-11 42.1 0.1 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 OAP59206.1 - 8.4e-10 38.6 0.1 1.8e-09 37.5 0.1 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 OAP59206.1 - 0.027 13.9 1.4 0.15 11.5 1.4 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF3425 PF11905.8 OAP59207.1 - 9.4e-24 83.8 0.0 1.6e-23 83.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_Maf PF03131.17 OAP59207.1 - 0.12 12.9 4.1 0.25 11.9 4.1 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor NmrA PF05368.13 OAP59208.1 - 5.4e-24 85.0 0.0 7.1e-24 84.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAP59208.1 - 3.1e-09 37.0 0.0 4.8e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 OAP59208.1 - 0.13 12.6 0.2 0.28 11.4 0.0 1.7 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain RhoGAP PF00620.27 OAP59209.1 - 8.1e-47 158.8 0.0 2.1e-46 157.5 0.0 1.7 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.23 OAP59209.1 - 7.1e-13 48.6 0.3 7.1e-13 48.6 0.3 2.2 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain T3SSipB PF16535.5 OAP59209.1 - 0.28 11.7 6.0 0.63 10.5 6.0 1.6 1 0 0 1 1 1 0 Type III cell invasion protein SipB HAUS-augmin3 PF14932.6 OAP59209.1 - 7.2 6.1 13.3 0.3 10.6 5.6 2.0 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 DUF745 PF05335.13 OAP59209.1 - 8.6 6.0 15.0 0.73 9.5 6.3 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF745) Clr5 PF14420.6 OAP59210.1 - 1.6e-14 53.9 0.1 4.5e-14 52.4 0.1 1.9 1 0 0 1 1 1 1 Clr5 domain TPR_12 PF13424.6 OAP59210.1 - 3.3e-11 43.3 1.1 7.6e-07 29.3 0.0 4.0 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 OAP59210.1 - 4.2e-09 36.0 4.9 0.011 15.6 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 OAP59210.1 - 0.00078 19.4 2.4 1 9.6 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 OAP59210.1 - 0.0039 17.1 2.3 0.02 14.9 0.1 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_MalT PF17874.1 OAP59210.1 - 0.038 13.3 0.1 0.39 10.0 0.0 2.1 2 0 0 2 2 2 0 MalT-like TPR region TPR_1 PF00515.28 OAP59210.1 - 0.11 12.3 0.2 2.2 8.3 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat FAD_binding_4 PF01565.23 OAP59211.1 - 3.7e-18 65.6 3.6 6.8e-18 64.8 3.6 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 OAP59211.1 - 4.4e-05 23.5 0.0 8.1e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Berberine and berberine like APH PF01636.23 OAP59211.1 - 0.014 15.4 0.0 0.021 14.7 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Hce2 PF14856.6 OAP59211.1 - 0.11 12.8 0.0 0.38 11.1 0.0 1.9 1 1 0 1 1 1 0 Pathogen effector; putative necrosis-inducing factor Helveticin_J PF17312.2 OAP59211.1 - 0.12 11.4 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 Bacteriocin helveticin-J Methyltransf_25 PF13649.6 OAP59212.1 - 1.8e-10 41.4 0.2 1.5e-09 38.4 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 OAP59212.1 - 4.3e-10 39.5 0.1 7.3e-10 38.7 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 OAP59212.1 - 4.1e-08 33.8 0.1 4.7e-07 30.4 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAP59212.1 - 2.1e-06 27.6 0.0 6.4e-06 26.0 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain MTS PF05175.14 OAP59212.1 - 7.6e-06 25.6 0.1 1.5e-05 24.6 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.7 OAP59212.1 - 1.8e-05 24.7 0.1 4.5e-05 23.4 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAP59212.1 - 6e-05 22.9 0.0 0.00013 21.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 OAP59212.1 - 0.00037 19.5 0.0 0.00072 18.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) PCMT PF01135.19 OAP59212.1 - 0.003 17.4 0.0 0.0053 16.5 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RasGAP_C PF03836.15 OAP59212.1 - 0.004 17.3 0.1 0.008 16.3 0.1 1.4 1 0 0 1 1 1 1 RasGAP C-terminus Met_10 PF02475.16 OAP59212.1 - 0.006 16.4 0.1 0.015 15.0 0.1 1.6 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_12 PF08242.12 OAP59212.1 - 0.0063 17.2 0.0 0.015 16.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 OAP59212.1 - 0.02 14.7 0.0 0.036 13.8 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase CMAS PF02353.20 OAP59212.1 - 0.051 12.9 0.0 0.078 12.3 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.18 OAP59212.1 - 0.071 12.4 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain TehB PF03848.14 OAP59212.1 - 0.15 11.5 0.1 0.29 10.5 0.1 1.5 2 0 0 2 2 2 0 Tellurite resistance protein TehB FAD_binding_3 PF01494.19 OAP59213.1 - 1.9e-29 103.1 0.0 3.4e-29 102.2 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAP59213.1 - 1.1e-06 28.5 0.9 0.0007 19.3 0.6 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAP59213.1 - 1.7e-06 28.1 0.2 6e-06 26.4 0.2 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAP59213.1 - 9.1e-06 25.1 0.2 0.00021 20.7 0.1 2.2 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAP59213.1 - 0.0001 21.6 0.4 0.00015 21.0 0.4 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 OAP59213.1 - 0.00029 21.3 0.2 0.0097 16.4 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 OAP59213.1 - 0.0027 16.8 0.0 0.24 10.4 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase Lycopene_cycl PF05834.12 OAP59213.1 - 0.0029 16.7 0.2 0.011 14.8 0.4 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein HI0933_like PF03486.14 OAP59213.1 - 0.0045 15.7 0.0 0.023 13.4 0.0 1.9 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 OAP59213.1 - 0.0084 15.4 0.1 0.013 14.8 0.1 1.3 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 OAP59213.1 - 0.026 13.6 0.3 0.041 13.0 0.3 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 OAP59213.1 - 0.062 12.6 0.5 0.13 11.5 0.3 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAP59213.1 - 0.089 12.8 0.3 2.1 8.3 0.2 2.6 3 0 0 3 3 3 0 FAD-NAD(P)-binding 3HCDH_N PF02737.18 OAP59213.1 - 0.11 12.4 0.1 0.18 11.6 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MFS_1 PF07690.16 OAP59214.1 - 1.5e-25 89.9 19.0 1.5e-25 89.9 19.0 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Presenilin PF01080.17 OAP59214.1 - 0.061 12.1 2.0 0.11 11.2 2.0 1.4 1 0 0 1 1 1 0 Presenilin HSP70 PF00012.20 OAP59216.1 - 1.9e-07 29.7 0.3 3.7e-07 28.7 0.1 1.5 2 0 0 2 2 2 1 Hsp70 protein Med7 PF05983.11 OAP59217.1 - 0.08 13.0 1.2 0.21 11.7 1.2 1.8 1 1 0 1 1 1 0 MED7 protein Syntaxin_2 PF14523.6 OAP59217.1 - 0.54 10.7 5.8 1.6 9.1 3.8 2.2 2 0 0 2 2 2 0 Syntaxin-like protein FAD_binding_3 PF01494.19 OAP59219.1 - 1.2e-21 77.4 0.0 5.5e-21 75.2 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 OAP59219.1 - 7.7e-07 29.3 0.6 1.6e-06 28.3 0.6 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAP59219.1 - 5e-05 22.7 0.1 0.0035 16.6 0.2 2.2 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAP59219.1 - 0.0021 17.2 0.7 0.0034 16.5 0.7 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAP59219.1 - 0.0053 16.4 3.1 0.018 14.6 2.7 2.0 2 1 1 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 OAP59219.1 - 0.044 14.3 0.1 0.087 13.4 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAP59219.1 - 0.045 13.0 0.2 0.074 12.3 0.2 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 OAP59219.1 - 0.051 12.8 0.7 0.081 12.2 0.7 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.21 OAP59219.1 - 0.074 12.4 0.4 0.14 11.4 0.4 1.4 1 0 0 1 1 1 0 ThiF family SE PF08491.10 OAP59219.1 - 0.095 11.7 0.0 0.19 10.7 0.0 1.5 1 1 0 1 1 1 0 Squalene epoxidase UDPG_MGDP_dh_N PF03721.14 OAP59219.1 - 0.12 12.0 0.4 0.25 10.9 0.4 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain GIDA PF01134.22 OAP59219.1 - 0.39 9.7 1.9 0.57 9.2 1.9 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Glyco_hydro_43 PF04616.14 OAP59220.1 - 6.2e-28 97.9 2.2 1.6e-18 67.1 0.4 2.4 2 1 0 2 2 2 2 Glycosyl hydrolases family 43 Amidohydro_3 PF07969.11 OAP59221.1 - 1.1e-76 259.2 4.2 1.4e-76 258.9 4.2 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 OAP59221.1 - 7.7e-17 61.6 0.0 1.9e-12 47.2 0.0 3.5 3 1 0 3 3 3 2 Amidohydrolase family DUF883 PF05957.13 OAP59222.1 - 0.02 15.5 1.2 0.034 14.7 0.5 1.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) PhyH PF05721.13 OAP59223.1 - 1.4e-28 100.6 0.3 1.8e-28 100.3 0.3 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 OAP59223.1 - 9.1e-05 22.8 0.0 0.00019 21.8 0.0 1.6 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase 2OG-FeII_Oxy_3 PF13640.6 OAP59223.1 - 0.0041 18.0 0.1 0.0086 16.9 0.1 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Phosphodiest PF01663.22 OAP59224.1 - 1e-29 104.3 0.0 1.9e-29 103.4 0.0 1.5 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase HD PF01966.22 OAP59224.1 - 7.4e-06 26.2 0.0 1.4e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 HD domain HD_4 PF13328.6 OAP59224.1 - 0.029 14.1 0.0 0.057 13.2 0.0 1.4 1 0 0 1 1 1 0 HD domain Zn_clus PF00172.18 OAP59225.1 - 9.6e-10 38.4 7.2 1.6e-09 37.7 7.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAP59225.1 - 3e-06 26.5 1.7 0.00011 21.3 0.2 2.5 1 1 1 2 2 2 2 Fungal specific transcription factor domain BRI3BP PF14965.6 OAP59225.1 - 0.09 12.3 0.2 0.22 11.0 0.2 1.6 1 0 0 1 1 1 0 Negative regulator of p53/TP53 Sugar_tr PF00083.24 OAP59226.1 - 4.7e-35 121.3 13.8 7.9e-35 120.6 13.8 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP59226.1 - 5.8e-19 68.2 27.7 9.6e-17 60.9 20.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2721 PF11026.8 OAP59226.1 - 0.17 11.8 0.2 0.17 11.8 0.2 3.9 5 0 0 5 5 5 0 Protein of unknown function (DUF2721) CytB6-F_Fe-S PF08802.10 OAP59226.1 - 0.28 11.3 3.3 2 8.5 0.2 3.2 2 0 0 2 2 2 0 Cytochrome B6-F complex Fe-S subunit Brix PF04427.18 OAP59228.1 - 4.7e-50 170.4 0.0 6.5e-50 169.9 0.0 1.2 1 0 0 1 1 1 1 Brix domain TFIIA PF03153.13 OAP59228.1 - 0.22 11.5 22.2 0.3 11.0 22.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1168 PF06658.12 OAP59228.1 - 0.65 9.8 30.3 0.1 12.4 13.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1168) UQ_con PF00179.26 OAP59229.1 - 5.4e-42 142.8 0.0 6.2e-42 142.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OAP59229.1 - 2.1e-05 24.2 0.0 2.8e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 OAP59229.1 - 0.023 15.0 0.0 0.025 14.8 0.0 1.3 1 0 0 1 1 1 0 RWD domain ChAPs PF09295.10 OAP59230.1 - 1.2e-149 498.7 0.0 1.6e-149 498.3 0.0 1.2 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_2 PF07719.17 OAP59230.1 - 0.00078 19.4 1.5 0.065 13.4 0.6 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 OAP59230.1 - 0.00087 19.9 4.3 3 8.9 0.1 4.5 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 OAP59230.1 - 0.0042 17.6 3.8 0.27 11.7 0.0 3.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 OAP59230.1 - 0.0083 15.9 0.6 2.4 8.1 0.2 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.6 OAP59230.1 - 0.02 14.1 6.0 0.13 11.4 0.4 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 OAP59230.1 - 0.033 14.4 0.0 1.9 8.9 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 OAP59230.1 - 0.091 13.1 5.9 1.2 9.4 0.2 3.7 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 OAP59230.1 - 0.11 12.6 3.0 28 5.1 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF1824 PF08854.10 OAP59230.1 - 0.16 11.9 0.0 0.42 10.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1824) Exonuc_VII_S PF02609.16 OAP59231.1 - 1.1 9.4 7.7 1.9 8.6 0.1 4.6 5 0 0 5 5 5 0 Exonuclease VII small subunit PseudoU_synth_1 PF01416.20 OAP59232.1 - 3.2e-34 117.7 0.0 1.2e-33 115.7 0.0 2.0 2 0 0 2 2 2 1 tRNA pseudouridine synthase PIG-H PF10181.9 OAP59233.1 - 1.4e-25 88.9 0.4 2.5e-25 88.1 0.4 1.4 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component ubiquitin PF00240.23 OAP59234.1 - 0.02 14.7 0.0 0.033 13.9 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin family YukD PF08817.10 OAP59234.1 - 0.069 13.8 0.0 0.12 13.1 0.0 1.4 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD Presenilin PF01080.17 OAP59234.1 - 3.1 6.5 5.8 4.2 6.0 5.8 1.3 1 0 0 1 1 1 0 Presenilin Pribosyl_synth PF14572.6 OAP59235.1 - 2.2e-43 148.5 2.1 2.2e-37 128.9 1.0 2.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 OAP59235.1 - 1.9e-32 111.6 0.0 4.7e-32 110.3 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 OAP59235.1 - 2.9e-14 52.9 0.6 5.2e-14 52.1 0.6 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 OAP59235.1 - 0.0077 15.7 1.6 0.0085 15.6 0.3 1.7 2 0 0 2 2 2 1 Uracil phosphoribosyltransferase Zn_clus PF00172.18 OAP59236.1 - 6.2e-06 26.2 5.3 1.2e-05 25.4 5.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 OAP59236.1 - 1e-05 24.6 0.2 2.2e-05 23.5 0.2 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain PSI_integrin PF17205.3 OAP59236.1 - 0.044 13.5 1.7 0.09 12.5 1.7 1.5 1 0 0 1 1 1 0 Integrin plexin domain RTA1 PF04479.13 OAP59237.1 - 9.7e-57 191.9 3.2 1.4e-56 191.4 3.2 1.2 1 0 0 1 1 1 1 RTA1 like protein TMEM208_SND2 PF05620.11 OAP59237.1 - 0.054 13.3 3.0 0.1 12.4 1.3 2.3 1 1 1 2 2 2 0 SRP-independent targeting protein 2/TMEM208 PMP1_2 PF08114.11 OAP59237.1 - 0.071 12.9 0.2 0.071 12.9 0.2 2.0 2 0 0 2 2 2 0 ATPase proteolipid family DUF4834 PF16118.5 OAP59237.1 - 5.9 7.9 7.9 1.7 9.6 0.7 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF4834) Closter_coat PF01785.17 OAP59238.1 - 0.11 11.7 0.5 2.8 7.2 0.2 2.1 2 0 0 2 2 2 0 Closterovirus coat protein vATP-synt_AC39 PF01992.16 OAP59239.1 - 6.9e-106 354.5 0.0 7.7e-106 354.4 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit GMC_oxred_C PF05199.13 OAP59240.1 - 2.6e-30 105.8 0.0 4.8e-30 105.0 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 OAP59240.1 - 1.5e-27 96.8 0.0 2.1e-24 86.4 0.0 2.9 1 1 1 2 2 2 2 GMC oxidoreductase Pyr_redox_2 PF07992.14 OAP59240.1 - 0.0003 20.1 0.0 0.00049 19.4 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAP59240.1 - 0.003 17.8 0.3 0.012 15.9 0.4 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 OAP59240.1 - 0.013 14.6 0.0 0.021 13.9 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_2 PF00890.24 OAP59240.1 - 0.059 12.4 0.1 0.1 11.7 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain FAD_binding_3 PF01494.19 OAP59240.1 - 0.069 12.4 0.2 0.12 11.6 0.2 1.4 1 0 0 1 1 1 0 FAD binding domain CFEM PF05730.11 OAP59241.1 - 7.1e-14 51.7 14.2 1.5e-13 50.6 14.2 1.6 1 0 0 1 1 1 1 CFEM domain Peroxidase_2 PF01328.17 OAP59242.1 - 1.6e-40 139.6 0.0 2.2e-40 139.2 0.0 1.2 1 0 0 1 1 1 1 Peroxidase, family 2 gp37_C PF12604.8 OAP59242.1 - 0.003 17.3 0.1 1.2 8.8 0.0 2.2 2 0 0 2 2 2 2 Tail fibre protein gp37 C terminal Fungal_trans PF04082.18 OAP59243.1 - 2.8e-11 43.0 0.0 4.8e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAD_binding_3 PF01494.19 OAP59244.1 - 4.4e-51 174.2 0.0 9.9e-51 173.0 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAP59244.1 - 4e-08 33.2 0.5 0.0061 16.2 0.0 2.7 3 0 0 3 3 3 2 FAD dependent oxidoreductase HI0933_like PF03486.14 OAP59244.1 - 5.7e-06 25.3 0.0 0.024 13.3 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox PF00070.27 OAP59244.1 - 0.00024 21.6 0.6 0.25 11.9 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAP59244.1 - 0.00057 19.2 0.1 0.14 11.4 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAP59244.1 - 0.0044 16.3 0.1 0.0093 15.2 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OAP59244.1 - 0.0095 15.0 0.7 0.9 8.5 0.1 2.6 3 0 0 3 3 3 1 Lycopene cyclase protein Thi4 PF01946.17 OAP59244.1 - 0.019 14.2 0.0 0.031 13.5 0.0 1.2 1 0 0 1 1 1 0 Thi4 family SE PF08491.10 OAP59244.1 - 0.029 13.4 0.0 0.068 12.2 0.0 1.6 2 0 0 2 2 2 0 Squalene epoxidase FAD_binding_2 PF00890.24 OAP59244.1 - 0.08 12.0 0.0 5.5 6.0 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain NAD_binding_8 PF13450.6 OAP59244.1 - 0.081 13.2 0.2 0.27 11.5 0.2 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain ApbA PF02558.16 OAP59244.1 - 0.18 11.5 0.1 0.31 10.7 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Trp_halogenase PF04820.14 OAP59244.1 - 0.2 10.4 0.5 0.67 8.7 0.1 1.8 2 0 0 2 2 2 0 Tryptophan halogenase Sugar_tr PF00083.24 OAP59246.1 - 7e-82 275.7 36.6 8.4e-82 275.4 36.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP59246.1 - 1.3e-31 109.8 27.1 1.3e-31 109.8 27.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily GET2 PF08690.10 OAP59246.1 - 3.3 7.3 5.0 2.6 7.6 0.1 2.2 2 0 0 2 2 2 0 GET complex subunit GET2 APH PF01636.23 OAP59247.1 - 5e-40 137.9 0.0 7.3e-40 137.4 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 OAP59247.1 - 0.00039 20.1 0.0 0.96 9.0 0.0 2.2 2 0 0 2 2 2 2 RIO1 family EcKinase PF02958.20 OAP59247.1 - 0.00082 18.8 0.0 0.0014 18.0 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase Pkinase PF00069.25 OAP59247.1 - 0.0062 15.9 0.0 2.4 7.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain p450 PF00067.22 OAP59248.1 - 2e-55 188.4 0.0 2.4e-55 188.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Lyase_1 PF00206.20 OAP59249.1 - 9e-103 343.9 0.0 1.8e-102 343.0 0.0 1.5 1 1 0 1 1 1 1 Lyase Fungal_trans PF04082.18 OAP59249.1 - 4.3e-20 71.8 0.1 6.6e-20 71.2 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain FumaraseC_C PF10415.9 OAP59249.1 - 5.1e-13 49.2 0.0 1.4e-12 47.8 0.0 1.8 1 0 0 1 1 1 1 Fumarase C C-terminus Cupin_2 PF07883.11 OAP59251.1 - 4.6e-18 64.7 1.4 2.2e-16 59.3 0.3 2.5 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.19 OAP59251.1 - 0.00012 22.0 0.5 0.0003 20.7 0.5 1.6 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_3 PF05899.12 OAP59251.1 - 0.0011 18.6 0.1 0.16 11.6 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF861) FAD_binding_3 PF01494.19 OAP59252.1 - 1.9e-21 76.7 0.1 3.8e-21 75.7 0.1 1.5 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 OAP59252.1 - 3e-08 33.3 2.8 0.00029 20.2 0.6 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAP59252.1 - 1.8e-05 24.8 0.2 4.5e-05 23.6 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAP59252.1 - 2.1e-05 24.3 5.2 0.0035 17.0 2.0 2.4 1 1 1 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 OAP59252.1 - 5.2e-05 22.5 0.8 6.4e-05 22.2 0.1 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein HI0933_like PF03486.14 OAP59252.1 - 0.00012 20.9 0.9 0.013 14.2 1.1 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 OAP59252.1 - 0.00029 21.3 2.4 0.0097 16.4 0.1 2.7 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAP59252.1 - 0.00046 19.4 1.1 0.00046 19.4 1.1 1.8 2 0 0 2 2 2 1 FAD binding domain Rossmann-like PF10727.9 OAP59252.1 - 0.0035 17.2 0.1 0.0096 15.8 0.1 1.7 1 0 0 1 1 1 1 Rossmann-like domain AlaDh_PNT_C PF01262.21 OAP59252.1 - 0.0087 15.4 0.3 0.021 14.1 0.3 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Amino_oxidase PF01593.24 OAP59252.1 - 0.0094 15.3 0.6 2.1 7.5 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase GIDA PF01134.22 OAP59252.1 - 0.024 13.7 2.8 0.038 13.1 2.8 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A 3HCDH_N PF02737.18 OAP59252.1 - 0.046 13.6 1.6 0.077 12.9 1.6 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.17 OAP59252.1 - 0.071 12.3 0.8 0.15 11.3 0.5 1.7 2 0 0 2 2 2 0 Thi4 family Pyr_redox_3 PF13738.6 OAP59252.1 - 0.16 11.2 0.2 0.32 10.2 0.2 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 OAP59252.1 - 0.31 9.9 3.2 2.4 6.9 0.0 2.2 1 1 0 2 2 2 0 Tryptophan halogenase Nop PF01798.18 OAP59253.1 - 2.9e-82 275.6 0.1 2.9e-82 275.6 0.1 2.2 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 OAP59253.1 - 1.4e-22 79.8 2.5 1.4e-22 79.8 2.5 2.5 2 0 0 2 2 2 1 NOP5NT (NUC127) domain HWE_HK PF07536.14 OAP59253.1 - 0.018 15.8 0.2 3.2 8.5 0.1 2.9 2 0 0 2 2 2 0 HWE histidine kinase dsrm PF00035.26 OAP59253.1 - 0.38 11.5 0.1 0.38 11.5 0.1 3.7 3 0 0 3 3 3 0 Double-stranded RNA binding motif RNA_pol_Rpb4 PF03874.16 OAP59254.1 - 1.1e-06 28.9 0.0 0.089 13.1 0.1 2.6 2 1 0 2 2 2 2 RNA polymerase Rpb4 TniB PF05621.11 OAP59254.1 - 0.094 12.1 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein PhaG_MnhG_YufB PF03334.14 OAP59254.1 - 0.22 11.8 0.1 0.7 10.2 0.0 1.7 2 0 0 2 2 2 0 Na+/H+ antiporter subunit PLAC8 PF04749.17 OAP59255.1 - 3.3e-26 92.2 18.5 3.9e-26 91.9 18.5 1.1 1 0 0 1 1 1 1 PLAC8 family Fungal_trans_2 PF11951.8 OAP59257.1 - 3.4e-05 22.8 0.0 6.8e-05 21.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain NABP PF07990.12 OAP59257.1 - 0.3 10.6 0.5 0.42 10.1 0.5 1.1 1 0 0 1 1 1 0 Nucleic acid binding protein NABP MFS_1 PF07690.16 OAP59258.1 - 2.9e-30 105.4 30.4 2.9e-30 105.4 30.4 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily GPHR_N PF12537.8 OAP59258.1 - 4.5 7.4 4.9 3.9 7.6 0.7 2.5 2 0 0 2 2 2 0 The Golgi pH Regulator (GPHR) Family N-terminal Sulfatase PF00884.23 OAP59259.1 - 2.2e-42 145.6 0.0 5.4e-41 141.0 0.0 2.3 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 OAP59259.1 - 8.5e-07 28.9 0.1 0.00026 20.7 0.1 2.3 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4976 PF16347.5 OAP59259.1 - 1.6e-05 25.1 0.5 9e-05 22.7 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4976) Sulfatase_C PF14707.6 OAP59259.1 - 0.063 14.0 0.0 0.15 12.8 0.0 1.6 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase Thioredox_DsbH PF03190.15 OAP59259.1 - 0.074 13.0 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF255 Herpes_MCP PF03122.14 OAP59259.1 - 0.32 8.4 0.0 0.46 7.9 0.0 1.1 1 0 0 1 1 1 0 Herpes virus major capsid protein FAD_binding_3 PF01494.19 OAP59260.1 - 1e-23 84.2 0.0 1.4e-23 83.7 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 OAP59260.1 - 9.9e-08 31.6 0.2 0.011 15.0 0.0 2.2 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAP59260.1 - 4e-06 26.2 0.1 6.3e-06 25.5 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 OAP59260.1 - 2e-05 24.7 1.3 4e-05 23.7 0.3 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAP59260.1 - 2.4e-05 24.1 1.9 0.00026 20.7 1.2 2.1 1 1 1 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 OAP59260.1 - 3e-05 23.2 1.1 0.00024 20.3 1.1 2.0 1 1 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 OAP59260.1 - 0.0002 20.7 0.0 0.026 13.8 0.0 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 OAP59260.1 - 0.0014 18.0 0.2 0.097 11.9 0.0 2.3 1 1 1 2 2 2 1 Flavin containing amine oxidoreductase Trp_halogenase PF04820.14 OAP59260.1 - 0.0015 17.4 0.5 0.46 9.3 0.0 2.4 2 0 0 2 2 2 2 Tryptophan halogenase ApbA PF02558.16 OAP59260.1 - 0.0016 18.1 0.1 0.0033 17.1 0.1 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA GIDA PF01134.22 OAP59260.1 - 0.0063 15.6 0.3 0.017 14.3 0.3 1.7 1 1 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.14 OAP59260.1 - 0.013 14.2 0.0 0.027 13.2 0.0 1.6 1 1 0 1 1 1 0 HI0933-like protein NAD_binding_9 PF13454.6 OAP59260.1 - 0.029 14.3 0.1 3.1 7.8 0.0 2.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding DUF1577 PF07614.11 OAP59260.1 - 0.13 11.4 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1577) Thi4 PF01946.17 OAP59260.1 - 0.13 11.5 0.1 0.22 10.8 0.1 1.3 1 0 0 1 1 1 0 Thi4 family AlaDh_PNT_C PF01262.21 OAP59260.1 - 0.18 11.0 0.6 0.44 9.8 0.6 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain SE PF08491.10 OAP59260.1 - 0.22 10.5 0.0 1.2 8.1 0.0 1.9 1 1 0 1 1 1 0 Squalene epoxidase Fungal_trans PF04082.18 OAP59261.1 - 2.7e-14 52.8 0.6 3.7e-14 52.4 0.6 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP59261.1 - 9.3e-05 22.5 3.3 0.00018 21.5 3.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.24 OAP59262.1 - 2.2e-84 284.0 15.1 2.6e-84 283.7 15.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP59262.1 - 3.7e-17 62.3 17.3 3.7e-17 62.3 17.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans_2 PF11951.8 OAP59264.1 - 4.2e-07 29.1 5.0 7.2e-07 28.3 0.6 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain DUF4381 PF14316.6 OAP59264.1 - 0.11 12.8 0.1 0.21 11.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Kringle PF00051.18 OAP59265.1 - 0.052 13.9 1.0 0.1 12.9 1.0 1.5 1 0 0 1 1 1 0 Kringle domain Crisp PF08562.10 OAP59266.1 - 0.27 11.9 1.7 0.38 11.4 0.6 1.7 2 0 0 2 2 2 0 Crisp Peptidase_C1_2 PF03051.15 OAP59267.1 - 1.7e-156 521.4 0.0 2.2e-156 521.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.23 OAP59267.1 - 6.1e-09 36.3 0.0 0.00021 21.4 0.0 2.7 2 1 0 2 2 2 2 Papain family cysteine protease UQ_con PF00179.26 OAP59268.1 - 2e-51 173.3 0.0 2.3e-51 173.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OAP59268.1 - 0.00088 19.0 0.0 0.00098 18.8 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 OAP59268.1 - 0.061 13.6 0.0 0.099 12.9 0.0 1.5 1 1 0 1 1 1 0 RWD domain Thiolase_N PF00108.23 OAP59269.1 - 3.9e-90 301.7 1.0 5.5e-90 301.3 1.0 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 OAP59269.1 - 5.3e-36 123.0 0.7 5.3e-36 123.0 0.7 2.0 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 OAP59269.1 - 3.8e-05 23.4 0.8 0.0001 22.0 0.8 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain DUF5419 PF17441.2 OAP59269.1 - 0.096 12.8 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5419) ACP_syn_III PF08545.10 OAP59269.1 - 0.81 9.6 8.3 4.8 7.1 0.3 3.3 4 0 0 4 4 4 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III His_Phos_1 PF00300.22 OAP59270.1 - 0.00072 19.3 1.3 4.8 6.8 0.0 3.6 3 1 0 3 3 3 3 Histidine phosphatase superfamily (branch 1) Ter PF05472.11 OAP59270.1 - 0.23 10.4 0.0 0.37 9.8 0.0 1.2 1 0 0 1 1 1 0 DNA replication terminus site-binding protein (Ter protein) Abhydrolase_6 PF12697.7 OAP59271.1 - 6.7e-10 39.9 1.2 8e-10 39.7 1.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAP59271.1 - 7.9e-07 29.0 0.0 1.3e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Kinesin PF00225.23 OAP59272.1 - 5.7e-107 357.5 0.2 5.7e-107 357.5 0.2 1.9 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 OAP59272.1 - 1.6e-27 96.3 0.1 5.1e-27 94.6 0.1 2.0 1 0 0 1 1 1 1 Microtubule binding Pro-kuma_activ PF09286.11 OAP59273.1 - 2.2e-29 102.6 0.0 3.3e-29 102.0 0.0 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 OAP59273.1 - 0.00068 19.0 0.0 0.0012 18.1 0.0 1.4 1 0 0 1 1 1 1 Subtilase family ABM PF03992.16 OAP59274.1 - 4.3e-06 26.8 1.1 5.8e-06 26.3 1.1 1.3 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase T5orf172 PF10544.9 OAP59275.1 - 6.2e-24 84.5 0.3 1.9e-23 83.0 0.3 1.8 1 0 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 OAP59275.1 - 2.3e-17 63.4 0.9 5.1e-17 62.3 0.9 1.6 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 ADH_zinc_N PF00107.26 OAP59276.1 - 4.3e-11 42.9 0.0 8e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAP59276.1 - 5.1e-09 37.3 0.0 1.2e-08 36.1 0.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAP59276.1 - 2.1e-06 27.6 0.2 0.00013 21.8 0.1 2.5 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.6 OAP59276.1 - 0.015 15.2 0.1 0.029 14.3 0.1 1.4 1 0 0 1 1 1 0 NAD(P)H-binding ADH_N_2 PF16884.5 OAP59276.1 - 0.023 14.6 0.0 0.063 13.2 0.0 1.7 1 1 0 1 1 1 0 N-terminal domain of oxidoreductase adh_short PF00106.25 OAP59276.1 - 0.059 12.8 0.1 0.095 12.1 0.1 1.3 1 0 0 1 1 1 0 short chain dehydrogenase RmlD_sub_bind PF04321.17 OAP59276.1 - 0.13 11.4 0.0 0.17 10.9 0.0 1.1 1 0 0 1 1 1 0 RmlD substrate binding domain FAD_binding_4 PF01565.23 OAP59277.1 - 3.2e-27 95.0 7.9 6e-27 94.1 7.9 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 OAP59277.1 - 3.3e-09 36.7 2.7 8e-09 35.5 2.7 1.6 1 0 0 1 1 1 1 Berberine and berberine like Peripla_BP_4 PF13407.6 OAP59277.1 - 0.011 15.4 0.1 0.019 14.5 0.1 1.4 1 0 0 1 1 1 0 Periplasmic binding protein domain AA_permease_2 PF13520.6 OAP59278.1 - 7e-66 222.8 48.4 8.9e-66 222.5 48.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAP59278.1 - 7.1e-17 61.1 39.7 1.1e-16 60.6 39.7 1.2 1 0 0 1 1 1 1 Amino acid permease Cupin_8 PF13621.6 OAP59279.1 - 1.2e-38 133.3 0.1 1.8e-38 132.7 0.1 1.3 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 OAP59279.1 - 3.7e-06 26.6 0.2 0.0013 18.3 0.0 2.2 2 0 0 2 2 2 2 Cupin superfamily protein JmjC PF02373.22 OAP59279.1 - 3.6e-05 24.1 0.1 7.2e-05 23.2 0.1 1.5 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 OAP59279.1 - 0.092 12.5 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Cupin domain RRM_1 PF00076.22 OAP59280.1 - 1.4e-27 95.3 0.0 1.2e-13 50.6 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OAP59280.1 - 0.00034 20.4 0.0 0.062 13.2 0.0 2.1 2 0 0 2 2 2 2 Occluded RNA-recognition motif RRM_3 PF08777.11 OAP59280.1 - 0.022 14.8 0.0 0.14 12.2 0.0 1.9 2 0 0 2 2 2 0 RNA binding motif DbpA PF03880.15 OAP59280.1 - 0.09 12.8 0.0 1.6 8.8 0.0 2.2 2 0 0 2 2 2 0 DbpA RNA binding domain CSD PF00313.22 OAP59280.1 - 0.13 12.1 0.2 0.39 10.6 0.0 1.8 2 0 0 2 2 2 0 'Cold-shock' DNA-binding domain SDA1 PF05285.12 OAP59281.1 - 0.39 10.1 5.0 0.11 11.9 1.5 1.8 2 0 0 2 2 2 0 SDA1 Spt20 PF12090.8 OAP59281.1 - 1.8 8.1 4.8 0.5 9.9 1.3 1.7 2 0 0 2 2 2 0 Spt20 family NOA36 PF06524.12 OAP59281.1 - 8.3 5.6 8.7 14 4.9 8.7 1.3 1 0 0 1 1 1 0 NOA36 protein Homeobox_KN PF05920.11 OAP59282.1 - 2.6e-16 59.3 0.4 8.1e-16 57.6 0.2 2.0 2 0 0 2 2 2 1 Homeobox KN domain Homeodomain PF00046.29 OAP59282.1 - 0.00045 20.0 1.8 0.00049 19.9 0.1 2.0 2 0 0 2 2 2 1 Homeodomain HTH_Tnp_Tc5 PF03221.16 OAP59282.1 - 0.00067 19.6 0.3 0.0017 18.4 0.3 1.8 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain zf-C2H2_4 PF13894.6 OAP59282.1 - 0.007 17.1 1.1 0.007 17.1 1.1 4.9 5 0 0 5 5 5 2 C2H2-type zinc finger zf-C2H2 PF00096.26 OAP59282.1 - 0.035 14.6 17.6 0.18 12.3 0.9 4.4 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_3rep PF18868.1 OAP59282.1 - 0.066 13.9 6.7 1.5 9.5 0.1 2.3 2 0 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats Elf1 PF05129.13 OAP59282.1 - 0.32 11.1 1.8 1.5 8.9 0.5 2.5 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like UQ_con PF00179.26 OAP59284.1 - 7.6e-08 32.1 0.4 1.5e-07 31.2 0.4 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 OAP59284.1 - 0.044 14.1 0.1 0.087 13.1 0.1 1.4 1 0 0 1 1 1 0 RWD domain 2OG-FeII_Oxy_2 PF13532.6 OAP59286.1 - 1e-34 120.5 0.0 1.4e-34 120.0 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-GRF PF06839.12 OAP59286.1 - 2.2e-08 34.0 7.6 4.8e-08 33.0 7.6 1.5 1 0 0 1 1 1 1 GRF zinc finger TPK_catalytic PF04263.16 OAP59286.1 - 0.1 12.6 0.0 0.31 11.1 0.0 1.7 2 0 0 2 2 2 0 Thiamin pyrophosphokinase, catalytic domain DUF4387 PF14330.6 OAP59287.1 - 1.7e-27 95.9 0.0 3.2e-27 95.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4387) AtuA PF07287.11 OAP59287.1 - 0.02 13.6 0.0 0.031 13.0 0.0 1.3 1 0 0 1 1 1 0 Acyclic terpene utilisation family protein AtuA TAL_FSA PF00923.19 OAP59288.1 - 1.3e-76 257.8 0.0 1.4e-76 257.6 0.0 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase Histone_H2A_C PF16211.5 OAP59288.1 - 0.15 11.8 0.1 0.29 10.9 0.1 1.5 1 0 0 1 1 1 0 C-terminus of histone H2A Sugar_tr PF00083.24 OAP59290.1 - 2.9e-92 309.9 19.3 3.4e-92 309.7 19.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP59290.1 - 2e-21 76.3 38.7 5.3e-18 65.1 11.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4293 PF14126.6 OAP59290.1 - 0.15 12.3 2.0 0.56 10.5 2.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4293) T2SSB PF16537.5 OAP59290.1 - 0.16 11.6 0.0 0.34 10.5 0.0 1.5 1 0 0 1 1 1 0 Type II secretion system protein B ox_reductase_C PF08635.10 OAP59291.1 - 5.1e-62 207.7 0.1 8.2e-62 207.0 0.1 1.3 1 0 0 1 1 1 1 Putative oxidoreductase C terminal domain GFO_IDH_MocA PF01408.22 OAP59291.1 - 2.1e-12 47.9 0.0 3.3e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 OAP59291.1 - 0.0014 18.6 0.0 0.0033 17.4 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Sugar_tr PF00083.24 OAP59292.1 - 9.6e-89 298.3 26.7 1.1e-88 298.1 26.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP59292.1 - 7e-16 58.1 48.5 2.9e-10 39.6 18.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Trypsin_2 PF13365.6 OAP59293.1 - 6.7e-05 23.8 0.0 0.00012 23.0 0.0 1.5 1 1 0 1 1 1 1 Trypsin-like peptidase domain Cyclase PF04199.13 OAP59294.1 - 3e-09 37.3 0.0 4.8e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 Putative cyclase adh_short_C2 PF13561.6 OAP59295.1 - 2.8e-40 138.4 1.6 5.2e-30 104.7 0.0 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP59295.1 - 6.9e-26 90.9 4.1 1.7e-12 47.2 0.4 2.2 1 1 1 2 2 2 2 short chain dehydrogenase KR PF08659.10 OAP59295.1 - 5.6e-13 49.2 3.6 5.9e-12 45.9 0.4 2.2 1 1 1 2 2 2 1 KR domain Epimerase PF01370.21 OAP59295.1 - 4.1e-07 29.7 0.3 6.2e-06 25.9 0.3 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAP59295.1 - 6.5e-06 25.8 0.0 0.0031 17.0 0.0 2.1 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase NmrA PF05368.13 OAP59295.1 - 0.0062 16.1 0.5 0.012 15.2 0.5 1.5 1 1 0 1 1 1 1 NmrA-like family 2-Hacid_dh_C PF02826.19 OAP59295.1 - 0.019 14.3 0.0 0.028 13.8 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NanE PF04131.14 OAP59295.1 - 0.038 13.2 0.1 0.057 12.6 0.1 1.3 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase TrkA_N PF02254.18 OAP59295.1 - 0.039 14.2 0.0 0.068 13.4 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain DapB_N PF01113.20 OAP59295.1 - 0.054 13.6 0.1 0.097 12.8 0.1 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus RmlD_sub_bind PF04321.17 OAP59295.1 - 0.059 12.5 0.0 0.11 11.5 0.0 1.5 2 0 0 2 2 2 0 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 OAP59295.1 - 0.079 12.1 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein YjeF_N PF03853.15 OAP59295.1 - 0.096 12.6 0.3 0.16 11.8 0.3 1.4 1 1 0 1 1 1 0 YjeF-related protein N-terminus 3HCDH_N PF02737.18 OAP59295.1 - 0.11 12.4 0.1 0.18 11.7 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DFP PF04127.15 OAP59295.1 - 0.12 12.2 0.1 0.2 11.4 0.1 1.4 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein TAL_FSA PF00923.19 OAP59296.1 - 7.5e-28 97.7 0.1 9.5e-28 97.4 0.1 1.1 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase WD40 PF00400.32 OAP59297.1 - 4.9e-17 62.0 17.6 0.0036 18.1 0.0 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.8 OAP59297.1 - 0.0028 16.4 0.6 0.25 10.0 0.1 2.6 1 1 1 3 3 3 2 Nucleoporin Nup120/160 PQQ_3 PF13570.6 OAP59297.1 - 0.026 15.0 0.5 4.3 8.0 0.1 3.8 4 0 0 4 4 4 0 PQQ-like domain eIF2A PF08662.11 OAP59297.1 - 0.053 13.4 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A Ribonuclease PF00545.20 OAP59298.1 - 6.5e-06 26.8 0.1 9.1e-06 26.3 0.1 1.2 1 0 0 1 1 1 1 ribonuclease AChE_tetra PF08674.10 OAP59298.1 - 0.18 11.5 0.2 0.18 11.5 0.2 1.9 2 0 0 2 2 2 0 Acetylcholinesterase tetramerisation domain Ccdc124 PF06244.12 OAP59299.1 - 5.7e-29 101.3 19.2 6e-28 98.0 19.2 2.1 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 TFIID-18kDa PF02269.16 OAP59300.1 - 1.1e-28 99.1 0.3 1.3e-27 95.6 0.1 2.2 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit CBFD_NFYB_HMF PF00808.23 OAP59300.1 - 0.0079 16.5 0.2 0.2 12.0 0.1 2.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TP_methylase PF00590.20 OAP59301.1 - 4e-23 82.5 0.1 1e-22 81.1 0.1 1.6 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases LamB_YcsF PF03746.16 OAP59302.1 - 2.2e-83 279.6 0.0 2.5e-83 279.4 0.0 1.0 1 0 0 1 1 1 1 LamB/YcsF family CT_A_B PF02626.15 OAP59303.1 - 7.6e-77 258.5 0.0 1.3e-76 257.7 0.0 1.4 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain A and B CPSase_L_D2 PF02786.17 OAP59303.1 - 1.9e-58 197.5 0.0 3.3e-58 196.6 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 OAP59303.1 - 1.6e-38 131.6 0.0 8.3e-38 129.3 0.1 2.2 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 OAP59303.1 - 1.9e-34 118.0 0.0 4.4e-34 116.8 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain CT_C_D PF02682.16 OAP59303.1 - 6.3e-22 78.3 0.0 1.2e-21 77.4 0.0 1.5 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain C and D Biotin_lipoyl PF00364.22 OAP59303.1 - 3.4e-11 42.8 0.6 1.4e-10 40.9 0.6 2.1 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 OAP59303.1 - 2.3e-07 30.6 0.0 5.3e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.6 OAP59303.1 - 8.2e-05 22.3 0.1 0.22 11.4 0.0 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like RimK PF08443.11 OAP59303.1 - 0.00031 20.4 0.0 0.0024 17.5 0.0 2.3 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp PF02222.22 OAP59303.1 - 0.0012 18.4 0.0 0.0024 17.5 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_5 PF13549.6 OAP59303.1 - 0.019 14.4 0.0 0.056 12.9 0.0 1.8 1 0 0 1 1 1 0 ATP-grasp domain HAUS5 PF14817.6 OAP59303.1 - 0.039 12.7 0.7 0.057 12.2 0.7 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 PLDc_2 PF13091.6 OAP59304.1 - 2.8e-19 69.3 0.0 3.8e-13 49.5 0.0 3.5 2 2 0 2 2 2 2 PLD-like domain PLDc PF00614.22 OAP59304.1 - 3.8e-05 23.7 0.1 0.016 15.4 0.0 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif FAM83 PF07894.12 OAP59304.1 - 0.0023 17.6 0.1 0.27 10.7 0.0 2.8 3 0 0 3 3 3 1 FAM83 A-H Regulator_TrmB PF11495.8 OAP59304.1 - 0.017 14.3 0.1 0.21 10.7 0.0 2.5 3 0 0 3 3 3 0 Archaeal transcriptional regulator TrmB p450 PF00067.22 OAP59305.1 - 2.4e-62 211.2 0.0 2.9e-62 210.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_23 PF13489.6 OAP59306.1 - 1.3e-21 77.2 0.0 1.9e-21 76.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAP59306.1 - 5.1e-10 39.9 0.0 1.1e-09 38.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAP59306.1 - 3.7e-08 33.9 0.0 7.4e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAP59306.1 - 6.6e-08 32.5 0.0 1.7e-06 27.9 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAP59306.1 - 5.8e-05 23.8 0.0 0.00018 22.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 OAP59306.1 - 0.022 14.2 0.0 0.031 13.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF938 PF06080.12 OAP59306.1 - 0.044 13.6 0.0 0.14 11.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF938) MTS PF05175.14 OAP59306.1 - 0.089 12.3 0.0 0.25 10.9 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_16 PF10294.9 OAP59306.1 - 0.14 11.9 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_2 PF00891.18 OAP59306.1 - 0.18 11.1 0.0 1.8 7.8 0.0 2.3 2 1 1 3 3 3 0 O-methyltransferase domain Methyltransf_23 PF13489.6 OAP59308.1 - 6.3e-20 71.7 0.1 1.8e-13 50.7 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 OAP59308.1 - 2.9e-06 27.9 0.0 6.9e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAP59308.1 - 0.00085 19.9 0.0 0.0026 18.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAP59308.1 - 0.0099 16.6 0.0 0.084 13.6 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain DAO PF01266.24 OAP59309.1 - 1.2e-38 133.6 0.3 1.6e-38 133.2 0.3 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 OAP59309.1 - 0.0006 19.8 0.6 0.049 13.6 0.0 2.6 2 1 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 OAP59309.1 - 0.0018 17.6 0.0 1.8 7.7 0.0 2.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAP59309.1 - 0.0064 15.6 0.2 0.044 12.9 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.22 OAP59309.1 - 0.19 10.8 0.0 0.36 9.9 0.0 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A TBP PF00352.21 OAP59310.1 - 1.2e-67 223.8 0.0 7.5e-33 112.3 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 OAP59310.1 - 0.00013 22.0 0.0 0.24 11.6 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) DUF4295 PF14128.6 OAP59310.1 - 0.045 13.6 0.1 0.26 11.2 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4295) ETF_QO PF05187.13 OAP59311.1 - 1.9e-25 89.0 0.0 3.2e-25 88.3 0.0 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S DAO PF01266.24 OAP59311.1 - 3.3e-08 33.5 0.8 0.00039 20.1 0.3 2.3 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAP59311.1 - 1.3e-07 31.7 0.0 4.7e-07 30.0 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 OAP59311.1 - 6.3e-06 25.6 0.0 0.00062 19.1 0.0 2.1 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.14 OAP59311.1 - 5.7e-05 22.5 0.0 0.00014 21.2 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAP59311.1 - 0.0001 21.5 2.0 0.0017 17.6 0.9 2.1 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.19 OAP59311.1 - 0.00026 20.4 0.4 0.00052 19.4 0.4 1.6 1 1 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 OAP59311.1 - 0.00051 18.9 0.6 0.00078 18.2 0.6 1.2 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_9 PF13454.6 OAP59311.1 - 0.00057 19.9 0.1 0.0024 17.9 0.1 2.0 3 0 0 3 3 3 1 FAD-NAD(P)-binding Amino_oxidase PF01593.24 OAP59311.1 - 0.0018 17.7 0.0 0.005 16.2 0.0 1.7 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 OAP59311.1 - 0.0019 17.5 0.4 0.0031 16.8 0.4 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAP59311.1 - 0.0042 17.6 1.5 2.2 8.9 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 OAP59311.1 - 0.055 12.8 0.0 0.089 12.1 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 OAP59311.1 - 0.056 12.5 0.3 0.083 11.9 0.3 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein K_oxygenase PF13434.6 OAP59311.1 - 0.092 11.9 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.14 OAP59311.1 - 0.11 11.4 0.3 1.7 7.4 0.2 2.1 2 0 0 2 2 2 0 Tryptophan halogenase AlaDh_PNT_C PF01262.21 OAP59311.1 - 0.16 11.2 0.0 0.26 10.5 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 OAP59311.1 - 0.19 10.8 0.2 0.3 10.1 0.2 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A adh_short PF00106.25 OAP59312.1 - 3.2e-30 105.0 0.3 8.6e-18 64.5 0.0 3.1 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAP59312.1 - 5.1e-25 88.4 0.0 2.9e-13 49.9 0.0 2.2 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP59312.1 - 0.00056 19.9 0.0 0.0011 19.0 0.0 1.4 1 0 0 1 1 1 1 KR domain Fe_hyd_lg_C PF02906.14 OAP59312.1 - 0.044 13.5 0.1 0.1 12.3 0.1 1.5 1 1 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain adh_short PF00106.25 OAP59313.1 - 5e-23 81.6 0.0 6.2e-22 78.0 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP59313.1 - 9.4e-13 48.3 0.0 1.7e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP59313.1 - 4.8e-06 26.6 0.1 7e-06 26.1 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAP59313.1 - 0.00022 20.7 0.0 0.0004 19.9 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAP59313.1 - 0.12 11.8 0.0 0.52 9.7 0.0 1.8 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase ABC2_membrane PF01061.24 OAP59314.1 - 7.7e-86 286.8 55.7 9.4e-44 149.3 16.6 2.9 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 OAP59314.1 - 1.9e-38 132.1 1.0 5.1e-20 72.4 0.0 3.1 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.12 OAP59314.1 - 7.9e-30 102.6 1.9 2e-25 88.5 0.0 3.0 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.6 OAP59314.1 - 9.4e-14 51.8 2.2 9.4e-14 51.8 2.2 3.1 3 1 0 3 3 1 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 OAP59314.1 - 1.1e-07 31.3 28.5 8.8e-06 25.1 12.1 2.7 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_18 PF13238.6 OAP59314.1 - 2.3e-06 28.2 0.0 0.00016 22.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 OAP59314.1 - 2.1e-05 24.5 0.3 0.0003 20.8 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 OAP59314.1 - 3.9e-05 24.1 0.1 0.021 15.2 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 OAP59314.1 - 4.2e-05 23.5 0.9 0.022 14.6 0.1 2.5 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 OAP59314.1 - 0.00025 20.7 0.4 0.091 12.3 0.2 2.7 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.6 OAP59314.1 - 0.00073 19.2 0.6 0.5 10.2 0.2 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 OAP59314.1 - 0.0011 19.0 0.0 0.073 13.2 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_28 PF13521.6 OAP59314.1 - 0.0015 18.8 0.0 0.0055 17.0 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 OAP59314.1 - 0.002 18.4 0.1 0.16 12.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 OAP59314.1 - 0.0024 18.0 0.0 0.052 13.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 OAP59314.1 - 0.0064 15.9 0.6 0.054 12.9 0.0 2.6 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain NACHT PF05729.12 OAP59314.1 - 0.0076 16.2 0.2 0.45 10.4 0.2 2.4 2 0 0 2 2 2 1 NACHT domain AAA_24 PF13479.6 OAP59314.1 - 0.021 14.5 0.2 0.24 11.1 0.1 2.6 3 0 0 3 3 3 0 AAA domain cobW PF02492.19 OAP59314.1 - 0.058 13.0 0.3 0.31 10.6 0.3 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Septin PF00735.18 OAP59314.1 - 0.091 12.0 0.1 0.4 9.9 0.1 1.9 2 0 0 2 2 2 0 Septin FtsK_SpoIIIE PF01580.18 OAP59314.1 - 0.11 11.8 1.9 9.5 5.5 0.3 2.7 3 0 0 3 3 2 0 FtsK/SpoIIIE family T2SSE PF00437.20 OAP59314.1 - 0.12 11.4 0.2 1.3 8.0 0.2 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein Dynamin_N PF00350.23 OAP59314.1 - 0.13 12.3 0.8 0.38 10.8 0.0 2.2 3 0 0 3 3 1 0 Dynamin family AAA_17 PF13207.6 OAP59314.1 - 0.15 12.5 0.2 7.7 6.9 0.1 2.8 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 OAP59314.1 - 0.25 11.0 3.7 4.9 6.8 0.5 2.8 3 0 0 3 3 3 0 AAA domain NB-ARC PF00931.22 OAP59314.1 - 0.43 9.7 1.4 5.5 6.1 0.3 2.3 2 0 0 2 2 2 0 NB-ARC domain Cwf_Cwc_15 PF04889.12 OAP59314.1 - 1.3 8.7 4.7 0.56 9.9 0.8 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein EMC3_TMCO1 PF01956.16 OAP59314.1 - 2.5 7.8 8.4 0.25 11.0 0.2 3.1 3 1 0 3 3 2 0 Integral membrane protein EMC3/TMCO1-like Glyco_hydro_72 PF03198.14 OAP59315.1 - 1.5e-83 280.6 0.5 2.3e-83 280.1 0.5 1.1 1 0 0 1 1 1 1 Glucanosyltransferase DUF4434 PF14488.6 OAP59315.1 - 0.17 11.9 0.1 0.27 11.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4434) GTA_TIM PF13547.6 OAP59316.1 - 0.0015 17.9 0.4 0.0023 17.3 0.4 1.2 1 0 0 1 1 1 1 GTA TIM-barrel-like domain Pkinase PF00069.25 OAP59317.1 - 5.7e-08 32.4 0.0 0.00014 21.3 0.0 2.6 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAP59317.1 - 3e-05 23.4 0.0 0.0036 16.6 0.0 2.9 2 1 0 2 2 2 2 Protein tyrosine kinase BCL9 PF11502.8 OAP59317.1 - 0.2 11.5 2.6 0.39 10.5 2.6 1.5 1 0 0 1 1 1 0 B-cell lymphoma 9 protein Ank_2 PF12796.7 OAP59319.1 - 5.1e-19 68.7 0.1 2e-08 34.7 0.1 4.0 2 1 4 6 6 6 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OAP59319.1 - 6.6e-16 58.2 2.3 8.6e-05 22.7 0.1 4.8 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 OAP59319.1 - 1.7e-14 53.9 0.3 2.2e-07 31.3 0.0 4.7 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAP59319.1 - 1e-11 43.9 0.4 0.031 14.8 0.0 6.5 6 0 0 6 6 5 2 Ankyrin repeat Ank PF00023.30 OAP59319.1 - 3e-10 40.1 0.0 0.044 14.3 0.0 5.5 4 0 0 4 4 4 2 Ankyrin repeat AAA_16 PF13191.6 OAP59319.1 - 1.2e-09 38.8 0.0 4.5e-09 36.9 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 OAP59319.1 - 1.2e-09 38.2 0.6 3.2e-09 36.9 0.1 2.1 2 0 0 2 2 1 1 NACHT domain AAA_22 PF13401.6 OAP59319.1 - 6.5e-06 26.5 0.1 3.6e-05 24.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain KAP_NTPase PF07693.14 OAP59319.1 - 0.0011 18.3 0.0 0.0088 15.3 0.0 2.1 1 1 1 2 2 2 1 KAP family P-loop domain DUF913 PF06025.12 OAP59319.1 - 0.0021 17.1 0.0 0.0037 16.3 0.0 1.3 1 0 0 1 1 1 1 Domain of Unknown Function (DUF913) ATPase_2 PF01637.18 OAP59319.1 - 0.042 13.8 0.0 0.1 12.5 0.0 1.7 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_19 PF13245.6 OAP59319.1 - 0.044 14.1 0.1 0.25 11.7 0.1 2.2 1 1 0 1 1 1 0 AAA domain TsaE PF02367.17 OAP59319.1 - 0.12 12.4 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Methyltransf_11 PF08241.12 OAP59320.1 - 2.5e-11 44.1 0.0 4.4e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAP59320.1 - 9.6e-09 35.8 0.0 2.4e-08 34.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAP59320.1 - 0.00065 20.4 0.0 0.00096 19.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 OAP59320.1 - 0.15 11.7 0.0 0.36 10.4 0.0 1.6 2 0 0 2 2 2 0 Nodulation protein S (NodS) HET PF06985.11 OAP59322.1 - 2.9e-11 43.9 0.2 5.5e-08 33.3 0.0 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Optomotor-blind PF11078.8 OAP59322.1 - 0.67 10.6 3.4 14 6.3 0.0 2.9 3 0 0 3 3 3 0 Optomotor-blind protein N-terminal region MFS_1 PF07690.16 OAP59323.1 - 5.7e-34 117.6 43.6 2.7e-32 112.1 31.0 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily Aldolase_II PF00596.21 OAP59324.1 - 3e-17 63.2 0.2 3.9e-17 62.8 0.2 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain An_peroxidase PF03098.15 OAP59325.1 - 4.7e-34 117.9 0.2 1.3e-18 66.9 0.0 4.3 2 1 2 4 4 4 3 Animal haem peroxidase p450 PF00067.22 OAP59325.1 - 4.7e-09 35.5 0.0 1.4e-08 34.0 0.0 1.7 2 0 0 2 2 2 1 Cytochrome P450 SR-25 PF10500.9 OAP59326.1 - 0.014 15.0 18.2 0.023 14.3 18.2 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RPN2_C PF18004.1 OAP59326.1 - 0.16 11.9 13.8 0.3 11.0 13.8 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain F-box-like PF12937.7 OAP59326.1 - 1.2 9.1 9.0 0.038 13.9 1.8 2.3 2 1 0 2 2 2 0 F-box-like RR_TM4-6 PF06459.12 OAP59326.1 - 1.4 8.7 10.0 2.1 8.1 10.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 AP3D1 PF06375.11 OAP59326.1 - 1.4 9.2 13.0 3.5 7.8 13.0 1.6 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 DUF3915 PF13054.6 OAP59326.1 - 1.8 8.5 5.3 4 7.4 5.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) RNA_polI_A34 PF08208.11 OAP59326.1 - 2.4 8.2 19.0 4.2 7.4 19.0 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 AAA PF00004.29 OAP59327.1 - 1.7e-40 138.5 0.0 3.9e-40 137.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 OAP59327.1 - 2.2e-18 66.0 0.2 4.3e-18 65.0 0.2 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 OAP59327.1 - 2.4e-09 36.9 0.1 5.6e-09 35.7 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 OAP59327.1 - 3.3e-05 23.9 0.8 0.00016 21.6 0.0 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OAP59327.1 - 0.00013 22.4 1.3 0.019 15.3 0.0 3.0 2 1 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 OAP59327.1 - 0.00024 20.9 0.0 0.00063 19.5 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 OAP59327.1 - 0.0026 17.9 1.8 0.0095 16.1 0.0 2.7 2 2 0 2 2 2 1 AAA domain (Cdc48 subfamily) PhoH PF02562.16 OAP59327.1 - 0.0027 17.2 0.3 0.065 12.7 0.1 2.4 2 0 0 2 2 2 1 PhoH-like protein AAA_22 PF13401.6 OAP59327.1 - 0.003 17.8 1.9 0.1 12.9 0.0 2.9 2 1 1 3 3 3 1 AAA domain Mg_chelatase PF01078.21 OAP59327.1 - 0.004 16.6 0.1 0.02 14.3 0.1 2.1 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 OAP59327.1 - 0.0044 16.2 1.0 0.018 14.2 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_33 PF13671.6 OAP59327.1 - 0.011 15.8 0.0 0.037 14.2 0.0 2.0 1 0 0 1 1 1 0 AAA domain JIP_LZII PF16471.5 OAP59327.1 - 0.015 15.5 5.1 0.046 13.9 5.1 1.8 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II IstB_IS21 PF01695.17 OAP59327.1 - 0.065 13.0 0.1 0.15 11.8 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_7 PF12775.7 OAP59327.1 - 0.16 11.5 0.3 0.45 10.0 0.0 1.9 2 1 0 2 2 2 0 P-loop containing dynein motor region AAA_11 PF13086.6 OAP59327.1 - 0.31 10.8 0.0 0.31 10.8 0.0 2.9 2 2 1 3 3 2 0 AAA domain CLZ PF16526.5 OAP59327.1 - 0.96 9.9 10.3 0.25 11.7 5.8 2.6 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Cyclin PF08613.11 OAP59328.1 - 2.8e-11 44.1 0.0 4e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 OAP59328.1 - 2.1e-05 24.3 0.0 3.4e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain CRC_subunit PF08624.10 OAP59329.1 - 1.5e-53 180.8 0.0 3.2e-53 179.8 0.0 1.5 2 0 0 2 2 2 1 Chromatin remodelling complex Rsc7/Swp82 subunit Pkinase PF00069.25 OAP59330.1 - 1.5e-69 234.3 0.0 2e-69 233.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP59330.1 - 9.5e-31 107.0 0.0 1.4e-30 106.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 OAP59330.1 - 1.9e-13 50.9 0.2 9.6e-13 48.6 0.2 2.3 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 OAP59330.1 - 1.8e-08 34.0 0.0 1.8e-07 30.8 0.0 2.0 1 1 1 2 2 2 1 Kinase-like C2 PF00168.30 OAP59330.1 - 3.7e-06 27.2 0.0 0.0025 18.1 0.0 2.6 2 0 0 2 2 2 2 C2 domain Haspin_kinase PF12330.8 OAP59330.1 - 0.00081 18.4 0.1 0.0017 17.4 0.1 1.4 1 1 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 OAP59330.1 - 0.0061 16.2 0.2 1.7 8.2 0.0 2.4 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 OAP59330.1 - 0.013 15.4 0.0 0.027 14.4 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 OAP59330.1 - 0.09 12.4 0.1 0.15 11.6 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Adeno_E3_15_3 PF03307.14 OAP59330.1 - 0.13 12.2 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Adenovirus 15.3kD protein in E3 region Kdo PF06293.14 OAP59330.1 - 0.14 11.5 0.1 0.22 10.9 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Cornifin PF02389.15 OAP59330.1 - 8.5 6.6 8.9 0.96 9.7 1.2 2.3 2 0 0 2 2 2 0 Cornifin (SPRR) family CsbD PF05532.12 OAP59331.1 - 0.052 13.5 0.5 0.078 12.9 0.5 1.3 1 0 0 1 1 1 0 CsbD-like zf-H2C2_5 PF13909.6 OAP59332.1 - 0.00016 21.3 6.4 0.029 14.1 1.6 3.7 3 0 0 3 3 3 2 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 OAP59332.1 - 0.0019 18.9 9.8 0.51 11.3 0.5 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 OAP59332.1 - 0.002 18.5 17.0 0.0038 17.6 0.7 3.8 3 1 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_11 PF16622.5 OAP59332.1 - 0.023 14.4 0.0 0.067 13.0 0.0 1.8 1 0 0 1 1 1 0 zinc-finger C2H2-type zf_C2H2_ZHX PF18387.1 OAP59332.1 - 0.072 12.7 0.5 3.3 7.4 0.1 2.3 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain CX9C PF16860.5 OAP59333.1 - 0.00045 20.2 0.9 0.00069 19.6 0.9 1.3 1 1 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, NDUF_B7 PF05676.13 OAP59333.1 - 0.0013 18.4 3.4 0.37 10.5 0.1 2.1 1 1 1 2 2 2 2 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) tRNA-synt_1 PF00133.22 OAP59334.1 - 2e-220 733.1 0.1 3.7e-220 732.3 0.1 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 OAP59334.1 - 9.3e-23 80.9 0.0 2.3e-21 76.3 0.0 2.7 3 0 0 3 3 3 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 OAP59334.1 - 1.3e-14 53.7 0.1 1.6e-05 23.8 0.0 3.9 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 OAP59334.1 - 0.00097 18.6 0.1 0.037 13.4 0.0 2.8 3 0 0 3 3 3 1 tRNA synthetases class I (C) catalytic domain HET PF06985.11 OAP59335.1 - 4.6e-23 82.2 0.0 1e-22 81.1 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) NAD_binding_2 PF03446.15 OAP59336.1 - 6.1e-30 104.5 0.0 9.2e-30 103.9 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 OAP59336.1 - 3.1e-14 53.3 0.1 5e-14 52.6 0.1 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase OCD_Mu_crystall PF02423.15 OAP59336.1 - 0.013 14.5 0.0 0.02 13.8 0.0 1.2 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family F420_oxidored PF03807.17 OAP59336.1 - 0.03 14.9 0.0 0.067 13.8 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Uso1_p115_head PF04869.14 OAP59337.1 - 2e-99 332.7 0.0 4.7e-99 331.5 0.0 1.7 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.13 OAP59337.1 - 4.8e-19 69.0 30.7 4.8e-19 69.0 30.7 3.7 1 1 1 2 2 2 1 Uso1 / p115 like vesicle tethering protein, C terminal region Atx10homo_assoc PF09759.9 OAP59337.1 - 0.0037 17.3 1.6 1.9 8.5 0.0 4.2 4 0 0 4 4 4 1 Spinocerebellar ataxia type 10 protein domain HEAT PF02985.22 OAP59337.1 - 0.12 12.7 3.0 13 6.4 0.0 3.8 4 0 0 4 4 4 0 HEAT repeat DUF3573 PF12097.8 OAP59337.1 - 0.18 10.6 2.2 0.4 9.5 2.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Acetyltransf_11 PF13720.6 OAP59337.1 - 2.2 8.8 0.0 2.2 8.8 0.0 4.3 4 1 0 4 4 4 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 AMP-binding PF00501.28 OAP59338.1 - 2.8e-83 279.9 0.0 3.8e-83 279.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAP59338.1 - 5e-12 46.6 0.0 9.7e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain XRN_M PF17846.1 OAP59339.1 - 4.9e-144 480.6 1.5 2.5e-143 478.2 0.0 2.4 2 1 0 2 2 2 1 Xrn1 helical domain XRN_N PF03159.18 OAP59339.1 - 3.5e-98 327.8 0.0 8.1e-98 326.7 0.0 1.6 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus zf-CCHC_2 PF13696.6 OAP59339.1 - 0.0079 16.0 1.4 0.02 14.7 1.4 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 OAP59339.1 - 0.016 15.3 2.9 0.033 14.3 2.9 1.5 1 0 0 1 1 1 0 Zinc knuckle DUF5540 PF17694.1 OAP59339.1 - 0.26 11.8 1.6 0.61 10.6 1.6 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5540) p450 PF00067.22 OAP59340.1 - 5.6e-53 180.3 0.0 6.4e-53 180.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 2-Hacid_dh_C PF02826.19 OAP59341.1 - 4.4e-43 146.7 0.0 6.8e-43 146.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 OAP59341.1 - 1.2e-06 28.2 0.0 2.5e-06 27.2 0.0 1.5 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AOC_like PF18678.1 OAP59341.1 - 0.019 14.6 0.1 0.038 13.6 0.1 1.4 1 0 0 1 1 1 0 Allene oxide cyclase barrel like domain F420_oxidored PF03807.17 OAP59341.1 - 0.065 13.8 0.0 0.19 12.4 0.0 1.7 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent ADH_N PF08240.12 OAP59342.1 - 1.3e-18 66.9 0.1 2.2e-18 66.2 0.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAP59342.1 - 8e-14 51.7 0.0 2e-13 50.4 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAP59342.1 - 0.0093 17.0 0.0 0.017 16.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 OAP59342.1 - 0.12 11.8 0.8 0.21 11.0 0.2 1.7 2 0 0 2 2 2 0 short chain dehydrogenase SAM_MT PF04445.13 OAP59342.1 - 0.26 10.7 1.3 0.45 9.9 0.3 1.7 2 0 0 2 2 2 0 Putative SAM-dependent methyltransferase Fungal_trans PF04082.18 OAP59343.1 - 2.6e-13 49.6 0.5 6e-13 48.4 0.5 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 OAP59343.1 - 5.1e-06 26.7 1.6 1.5e-05 25.2 1.6 1.9 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAP59343.1 - 0.0029 18.3 1.0 0.0098 16.7 1.0 2.0 1 0 0 1 1 1 1 C2H2-type zinc finger Inhibitor_Mig-6 PF11555.8 OAP59343.1 - 0.042 14.0 1.3 0.16 12.1 1.3 2.0 1 0 0 1 1 1 0 EGFR receptor inhibitor Mig-6 zf-Di19 PF05605.12 OAP59343.1 - 0.11 12.8 0.1 0.22 11.8 0.1 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.6 OAP59343.1 - 0.26 11.8 3.1 1.2 9.7 0.7 2.5 2 0 0 2 2 2 0 Zinc-finger double domain tRNA-synt_2b PF00587.25 OAP59344.1 - 2.2e-21 76.6 0.0 3.4e-19 69.5 0.0 2.9 2 1 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 OAP59344.1 - 2.5e-07 30.9 1.5 4.6e-07 30.0 1.5 1.4 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain ATG16 PF08614.11 OAP59344.1 - 0.004 17.4 1.5 0.0065 16.7 1.5 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) APG6_N PF17675.1 OAP59344.1 - 0.18 12.3 0.7 0.32 11.5 0.7 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region Macoilin PF09726.9 OAP59344.1 - 0.33 9.5 0.7 0.46 9.0 0.7 1.1 1 0 0 1 1 1 0 Macoilin family Abhydrolase_1 PF00561.20 OAP59345.1 - 3.1e-21 76.2 0.2 5.2e-21 75.4 0.2 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAP59345.1 - 3e-19 70.5 1.2 4.4e-19 70.0 1.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAP59345.1 - 4.5e-07 29.4 0.0 8.6e-07 28.5 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 OAP59345.1 - 0.11 11.2 0.0 0.18 10.5 0.0 1.3 1 0 0 1 1 1 0 Ndr family Epimerase PF01370.21 OAP59346.1 - 1.8e-13 50.5 0.0 2.9e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAP59346.1 - 1.2e-06 28.1 0.0 2e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 OAP59346.1 - 1.1e-05 24.7 0.0 0.00034 19.9 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 OAP59346.1 - 0.0026 17.7 0.0 0.0039 17.1 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 OAP59346.1 - 0.0094 15.1 0.0 0.021 13.9 0.0 1.5 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 OAP59346.1 - 0.036 13.1 0.0 0.059 12.4 0.0 1.3 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Zn_clus PF00172.18 OAP59347.1 - 0.00098 19.2 11.1 0.002 18.2 11.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAP59347.1 - 0.009 15.1 0.0 0.016 14.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain TPR_MalT PF17874.1 OAP59347.1 - 0.028 13.8 0.0 0.048 13.0 0.0 1.3 1 0 0 1 1 1 0 MalT-like TPR region Aldolase_II PF00596.21 OAP59348.1 - 2.2e-39 135.3 1.5 4.2e-39 134.4 1.5 1.4 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Peptidase_C41 PF05417.11 OAP59348.1 - 0.014 15.2 0.3 0.026 14.3 0.3 1.4 1 0 0 1 1 1 0 Hepatitis E cysteine protease CTP_transf_1 PF01148.20 OAP59349.1 - 0.0005 19.9 0.9 0.00072 19.4 0.9 1.2 1 0 0 1 1 1 1 Cytidylyltransferase family Fructosamin_kin PF03881.14 OAP59350.1 - 9.1e-31 107.1 0.0 1.1e-30 106.8 0.0 1.1 1 0 0 1 1 1 1 Fructosamine kinase PQQ_2 PF13360.6 OAP59351.1 - 9.5e-06 25.4 0.5 0.00034 20.3 0.0 3.2 4 1 1 5 5 5 1 PQQ-like domain Abhydrolase_6 PF12697.7 OAP59351.1 - 0.00027 21.6 0.1 0.0007 20.3 0.1 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.14 OAP59351.1 - 0.0021 17.6 0.0 0.0038 16.8 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 OAP59351.1 - 0.0028 17.4 0.0 0.0077 16.0 0.0 1.6 2 0 0 2 2 2 1 PGAP1-like protein DUF359 PF04019.12 OAP59351.1 - 0.022 14.4 0.0 0.066 12.9 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF359) Hydrolase_4 PF12146.8 OAP59351.1 - 0.045 13.0 0.0 0.089 12.0 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 NACHT PF05729.12 OAP59351.1 - 0.051 13.5 0.0 0.16 11.9 0.0 1.8 2 0 0 2 2 2 0 NACHT domain Zeta_toxin PF06414.12 OAP59351.1 - 0.19 11.0 0.0 0.35 10.1 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin WD40 PF00400.32 OAP59351.1 - 0.28 12.1 1.5 22 6.1 0.2 4.5 5 0 0 5 5 5 0 WD domain, G-beta repeat MFS_1 PF07690.16 OAP59352.1 - 8.9e-42 143.3 19.7 8.9e-42 143.3 19.7 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAP59352.1 - 4.5e-08 32.4 3.4 4.5e-08 32.4 3.4 1.7 2 0 0 2 2 2 1 Sugar (and other) transporter Cortexin PF11057.8 OAP59352.1 - 0.041 13.7 0.0 0.041 13.7 0.0 1.8 2 0 0 2 2 2 0 Cortexin of kidney Abhydrolase_6 PF12697.7 OAP59353.1 - 1.1e-10 42.5 14.3 1.4e-08 35.6 14.3 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAP59353.1 - 7.7e-10 38.8 0.0 2.6e-08 33.8 0.0 2.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Iso_dh PF00180.20 OAP59354.1 - 6.5e-88 295.2 0.0 7.4e-88 295.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Tape_meas_lam_C PF09718.10 OAP59354.1 - 0.041 14.0 0.3 0.074 13.2 0.3 1.4 1 0 0 1 1 1 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) EIIA-man PF03610.16 OAP59354.1 - 0.094 13.0 0.1 0.15 12.3 0.1 1.3 1 0 0 1 1 1 0 PTS system fructose IIA component DEAD PF00270.29 OAP59355.1 - 2.6e-36 125.0 0.0 1.8e-35 122.3 0.0 2.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.6 OAP59355.1 - 1.5e-20 73.2 0.0 3.1e-20 72.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.31 OAP59355.1 - 2.7e-18 66.3 0.0 7e-18 65.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAP59355.1 - 2.5e-05 24.4 0.0 0.0002 21.4 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 OAP59355.1 - 0.039 14.2 0.8 0.44 10.8 0.1 2.7 2 1 0 2 2 2 0 AAA domain Fungal_trans PF04082.18 OAP59356.1 - 8.3e-30 103.7 0.9 1.9e-29 102.5 0.0 2.1 3 0 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP59356.1 - 1.8e-09 37.5 11.3 3.2e-09 36.8 11.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 OAP59357.1 - 5.8e-36 124.1 18.0 5.8e-36 124.1 18.0 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAP59357.1 - 4.8e-07 29.0 5.0 4.8e-07 29.0 5.0 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 OAP59357.1 - 0.019 13.4 0.9 0.03 12.7 0.9 1.2 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 OAP59357.1 - 7.7 4.8 13.0 0.87 7.9 3.4 2.8 2 1 1 3 3 3 0 Transmembrane secretion effector CoA_transf_3 PF02515.17 OAP59358.1 - 6.6e-108 361.1 0.1 3.4e-105 352.2 0.0 2.2 2 0 0 2 2 2 2 CoA-transferase family III TRI12 PF06609.13 OAP59359.1 - 1.1e-36 126.5 25.8 1.4e-36 126.1 25.8 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAP59359.1 - 9.2e-22 77.4 50.4 1.5e-21 76.7 47.8 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAP59359.1 - 2.1e-12 46.6 28.4 8.7e-10 38.0 10.3 2.5 2 0 0 2 2 2 2 Sugar (and other) transporter Fungal_trans PF04082.18 OAP59360.1 - 6.5e-24 84.4 0.4 1.1e-23 83.6 0.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP59360.1 - 3.3e-07 30.3 4.5 6.1e-07 29.5 4.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_C14 PF00656.22 OAP59361.1 - 6.6e-44 150.7 0.0 1e-43 150.1 0.0 1.2 1 1 0 1 1 1 1 Caspase domain Pilin_N PF07790.11 OAP59362.1 - 0.013 16.4 1.0 0.028 15.3 1.0 1.5 1 0 0 1 1 1 0 Archaeal Type IV pilin, N-terminal DUF3169 PF11368.8 OAP59362.1 - 0.21 11.0 0.4 0.36 10.3 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) EpuA PF11772.8 OAP59362.1 - 6.9 6.4 7.1 12 5.7 7.1 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta PT-VENN PF04829.13 OAP59362.1 - 8.2 6.6 6.3 18 5.5 6.3 1.5 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif Presenilin PF01080.17 OAP59364.1 - 0.79 8.4 3.2 0.95 8.2 3.2 1.0 1 0 0 1 1 1 0 Presenilin Ish1 PF10281.9 OAP59365.1 - 2.2e-96 315.8 20.3 1.2e-14 54.3 0.1 7.6 7 0 0 7 7 7 7 Putative stress-responsive nuclear envelope protein HeH PF12949.7 OAP59365.1 - 1.6e-13 50.1 0.0 0.0004 20.0 0.0 6.2 6 0 0 6 6 6 2 HeH/LEM domain SAP PF02037.27 OAP59365.1 - 2.1e-11 43.3 0.0 0.17 11.7 0.0 7.1 7 0 0 7 7 7 3 SAP domain Slx4 PF09494.10 OAP59365.1 - 8.8e-06 25.6 0.2 22 5.1 0.0 5.7 6 0 0 6 6 6 0 Slx4 endonuclease ANAPC2 PF08672.11 OAP59365.1 - 1.1e-05 25.8 0.8 40 4.8 0.0 6.5 7 0 0 7 7 7 0 Anaphase promoting complex (APC) subunit 2 Thymopoietin PF08198.11 OAP59365.1 - 0.00014 21.4 0.1 11 5.7 0.0 4.5 4 0 0 4 4 4 1 Thymopoietin protein SAM_2 PF07647.17 OAP59365.1 - 0.00018 21.6 2.9 23 5.2 0.0 6.1 6 0 0 6 6 6 0 SAM domain (Sterile alpha motif) LEM PF03020.15 OAP59365.1 - 0.0016 17.9 0.0 3.6 7.2 0.0 4.4 4 0 0 4 4 4 1 LEM domain SAP30_Sin3_bdg PF13867.6 OAP59365.1 - 0.084 13.2 6.7 0.8 10.1 0.0 4.3 6 0 0 6 6 6 0 Sin3 binding region of histone deacetylase complex subunit SAP30 ATR13 PF16829.5 OAP59365.1 - 0.11 12.9 0.1 0.65 10.4 0.2 2.2 2 0 0 2 2 2 0 Avirulence protein ATR13, RxLR effector Homeobox_KN PF05920.11 OAP59365.1 - 0.12 12.3 0.8 10 6.1 0.1 4.0 4 0 0 4 4 4 0 Homeobox KN domain DUF3612 PF12268.8 OAP59365.1 - 0.12 12.4 0.0 41 4.2 0.0 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF3612) DUF4125 PF13526.6 OAP59365.1 - 0.21 11.2 2.4 6.5 6.3 0.4 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF4125) DUF2795 PF11387.8 OAP59365.1 - 0.56 10.5 8.8 11 6.3 0.1 4.9 5 0 0 5 5 5 0 Protein of unknown function (DUF2795) Recombinase PF07508.13 OAP59365.1 - 1.8 9.0 9.1 18 5.8 1.8 4.2 2 2 1 3 3 3 0 Recombinase Cyt-b5 PF00173.28 OAP59366.1 - 5.9e-16 58.4 0.0 7.9e-16 58.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Sugar_tr PF00083.24 OAP59367.1 - 2.8e-41 141.8 10.9 1.2e-40 139.7 10.9 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP59367.1 - 8.8e-25 87.4 34.1 1.8e-23 83.0 19.2 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily SesA PF17107.5 OAP59368.1 - 3e-06 27.4 0.3 5.3e-06 26.6 0.3 1.4 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases SMN PF06003.12 OAP59368.1 - 0.005 16.1 1.4 0.0089 15.3 1.4 1.3 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) Utp12 PF04003.12 OAP59368.1 - 0.019 15.3 0.1 0.06 13.7 0.1 1.8 1 0 0 1 1 1 0 Dip2/Utp12 Family MbeD_MobD PF04899.12 OAP59368.1 - 0.074 13.2 0.8 0.32 11.1 0.8 2.0 1 1 0 1 1 1 0 MbeD/MobD like KxDL PF10241.9 OAP59368.1 - 0.13 12.5 0.2 0.37 11.1 0.2 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein Lum_binding PF00677.17 OAP59369.1 - 1.3e-43 146.9 0.6 4.4e-21 74.7 0.2 2.4 2 0 0 2 2 2 2 Lumazine binding domain TPP_enzyme_N PF02776.18 OAP59370.1 - 1.5e-54 184.2 0.0 2.2e-53 180.4 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 OAP59370.1 - 1.8e-47 161.0 0.4 4.1e-45 153.3 0.0 2.8 3 0 0 3 3 3 2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 OAP59370.1 - 7.8e-40 135.8 0.2 1.8e-39 134.6 0.2 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain Allantoicase PF03561.15 OAP59371.1 - 3.7e-89 296.1 0.1 2.6e-45 153.9 0.0 2.1 2 0 0 2 2 2 2 Allantoicase repeat DUF5035 PF16438.5 OAP59371.1 - 0.12 12.2 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5035) MFS_1 PF07690.16 OAP59372.1 - 1.1e-40 139.7 37.0 1.7e-40 139.0 31.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAP59372.1 - 1.6e-05 24.0 11.3 1.6e-05 24.0 11.3 3.0 3 1 0 3 3 3 1 Sugar (and other) transporter OATP PF03137.20 OAP59372.1 - 0.0084 14.5 1.0 0.046 12.0 0.7 2.2 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family AMP-binding PF00501.28 OAP59373.1 - 6.1e-99 331.5 0.0 7.1e-99 331.2 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAP59373.1 - 3e-11 44.2 0.9 5.7e-10 40.0 0.4 2.6 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DUF547 PF04784.14 OAP59373.1 - 0.21 11.7 0.0 0.74 9.9 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF547 GalKase_gal_bdg PF10509.9 OAP59374.1 - 1.9e-19 68.9 0.0 4.1e-19 67.9 0.0 1.6 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.26 OAP59374.1 - 2.5e-14 53.2 2.6 5.3e-14 52.2 2.6 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 OAP59374.1 - 4.6e-13 49.3 0.0 1.7e-12 47.5 0.0 2.0 1 0 0 1 1 1 1 GHMP kinases C terminal HTH_7 PF02796.15 OAP59374.1 - 0.019 15.1 0.0 0.042 13.9 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_23 PF13384.6 OAP59374.1 - 0.051 13.4 0.0 0.13 12.1 0.0 1.7 1 0 0 1 1 1 0 Homeodomain-like domain Phage_antiter_Q PF06323.11 OAP59374.1 - 0.057 12.9 0.0 0.094 12.2 0.0 1.2 1 0 0 1 1 1 0 Phage antitermination protein Q Sigma70_r4_2 PF08281.12 OAP59374.1 - 0.11 12.2 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_3 PF01381.22 OAP59374.1 - 0.14 12.2 0.8 0.41 10.7 0.1 2.2 3 0 0 3 3 3 0 Helix-turn-helix DUF2316 PF10078.9 OAP59374.1 - 0.15 12.3 0.0 10 6.4 0.0 2.3 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2316) RINGv PF12906.7 OAP59375.1 - 5.7e-06 26.3 7.2 1.1e-05 25.4 7.2 1.5 1 0 0 1 1 1 1 RING-variant domain MRP-L28 PF09812.9 OAP59375.1 - 1.2e-05 25.5 0.0 1.8e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 FANCL_C PF11793.8 OAP59375.1 - 4.6e-05 23.5 3.8 9.6e-05 22.5 3.8 1.4 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING_2 PF13639.6 OAP59375.1 - 0.051 13.9 6.9 0.092 13.1 6.9 1.5 1 0 0 1 1 1 0 Ring finger domain Ras PF00071.22 OAP59376.1 - 6.8e-50 168.8 0.0 7.9e-50 168.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAP59376.1 - 4.1e-22 78.7 0.0 5.8e-22 78.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAP59376.1 - 3e-07 30.1 0.0 4.7e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 OAP59376.1 - 0.0016 17.9 0.0 0.0021 17.5 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 OAP59376.1 - 0.013 14.8 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 OAP59376.1 - 0.051 13.3 0.0 3 7.6 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 OAP59376.1 - 0.093 12.8 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_21 PF13304.6 OAP59376.1 - 0.21 11.3 0.0 0.25 11.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system NST1 PF13945.6 OAP59377.1 - 6.1e-60 202.6 5.4 6.1e-60 202.6 5.4 4.3 3 1 1 4 4 4 1 Salt tolerance down-regulator GTP1_OBG PF01018.22 OAP59378.1 - 1.7e-39 134.9 1.0 5.6e-29 100.7 2.6 2.3 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.23 OAP59378.1 - 4.1e-21 75.2 0.0 6.8e-21 74.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OAP59378.1 - 9.5e-05 22.0 0.2 0.00042 19.9 0.0 2.0 2 1 0 3 3 3 1 Ferrous iron transport protein B MeaB PF03308.16 OAP59378.1 - 0.03 13.3 0.1 2.7 6.9 0.0 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 OAP59378.1 - 0.15 12.7 0.0 0.31 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Lactamase_B PF00753.27 OAP59379.1 - 5.7e-05 23.2 0.9 0.00013 22.1 0.8 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OAP59379.1 - 0.0032 17.0 0.5 0.006 16.1 0.2 1.7 2 1 0 2 2 2 1 Beta-lactamase superfamily domain MerB PF03243.15 OAP59379.1 - 0.16 12.1 0.0 0.28 11.3 0.0 1.3 1 0 0 1 1 1 0 Alkylmercury lyase Aconitase PF00330.20 OAP59380.1 - 1.5e-146 489.0 0.0 1.8e-146 488.8 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 OAP59380.1 - 1.5e-32 112.7 0.0 2.7e-32 111.8 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain Iso_dh PF00180.20 OAP59381.1 - 3.9e-97 325.5 0.0 4.5e-97 325.3 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase MFS_1 PF07690.16 OAP59382.1 - 4.3e-33 114.7 21.9 6.6e-33 114.1 21.9 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4064 PF13273.6 OAP59382.1 - 0.16 12.2 4.8 0.64 10.3 0.5 3.4 3 2 0 3 3 3 0 Protein of unknown function (DUF4064) p450 PF00067.22 OAP59384.1 - 1.8e-68 231.4 0.0 2.2e-68 231.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sfi1 PF08457.10 OAP59385.1 - 1.9e-42 145.6 64.3 3.3e-23 82.1 29.3 3.4 1 1 2 3 3 3 3 Sfi1 spindle body protein Phage_P2_GpE PF06528.12 OAP59385.1 - 8.5 6.0 9.0 3.8 7.1 0.5 3.9 3 0 0 3 3 3 0 Phage P2 GpE Glyco_hydro_43 PF04616.14 OAP59386.1 - 4e-30 105.1 0.0 5e-30 104.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 DUF5348 PF17295.2 OAP59386.1 - 0.13 12.2 0.5 1.1 9.2 0.5 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF5348) Arylesterase PF01731.20 OAP59387.1 - 0.0017 18.5 0.1 0.0042 17.3 0.1 1.8 1 1 0 1 1 1 1 Arylesterase Glyco_hydro_42C PF08533.10 OAP59387.1 - 0.076 12.8 0.1 0.28 10.9 0.0 1.9 2 0 0 2 2 2 0 Beta-galactosidase C-terminal domain Transp_cyt_pur PF02133.15 OAP59388.1 - 8.1e-97 324.8 37.9 9.5e-97 324.5 37.9 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin PARP PF00644.20 OAP59390.1 - 6.7e-10 38.9 0.0 1.4e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain UQ_con PF00179.26 OAP59390.1 - 6.8e-09 35.5 0.0 1.6e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme BCSC_C PF05420.11 OAP59390.1 - 0.018 14.2 0.2 0.029 13.5 0.2 1.2 1 0 0 1 1 1 0 Cellulose synthase operon protein C C-terminus (BCSC_C) Ribosomal_L27e PF01777.18 OAP59392.1 - 4.9e-38 129.4 4.8 7.5e-38 128.8 4.8 1.3 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 OAP59392.1 - 0.0069 16.3 0.5 0.017 15.0 0.5 1.7 1 0 0 1 1 1 1 KOW motif UBA_2 PF08587.11 OAP59393.1 - 0.018 15.1 7.3 16 5.7 0.0 6.6 6 1 1 7 7 7 0 Ubiquitin associated domain (UBA) CMD PF02627.20 OAP59393.1 - 0.093 12.8 2.3 0.81 9.8 0.1 3.7 3 0 0 3 3 3 0 Carboxymuconolactone decarboxylase family M PF02370.16 OAP59393.1 - 1.9 9.3 4.6 14 6.6 0.1 3.7 2 0 0 2 2 2 0 M protein repeat Imm1 PF14430.6 OAP59393.1 - 2.7 8.6 4.7 5.1 7.8 0.2 4.0 3 0 0 3 3 3 0 Immunity protein Imm1 Scaffolding_pro PF11418.8 OAP59393.1 - 4.3 8.0 8.3 1.3 9.6 1.7 3.8 4 0 0 4 4 4 0 Phi29 scaffolding protein TRAM_LAG1_CLN8 PF03798.16 OAP59394.1 - 1.6e-51 174.9 9.7 2.1e-51 174.5 9.7 1.1 1 0 0 1 1 1 1 TLC domain Rhomboid PF01694.22 OAP59394.1 - 0.47 10.4 5.1 2.5 8.1 0.4 2.7 3 0 0 3 3 3 0 Rhomboid family Mo25 PF08569.11 OAP59395.1 - 2.2e-121 405.3 0.2 2.5e-121 405.1 0.2 1.0 1 0 0 1 1 1 1 Mo25-like Ndc80_HEC PF03801.13 OAP59396.1 - 3.9e-59 198.7 0.1 7.5e-59 197.8 0.1 1.5 1 0 0 1 1 1 1 HEC/Ndc80p family DUF3584 PF12128.8 OAP59396.1 - 0.00016 19.4 5.5 0.00016 19.4 5.5 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3584) Filament PF00038.21 OAP59396.1 - 0.0013 18.4 40.3 0.039 13.5 24.2 2.5 2 0 0 2 2 2 2 Intermediate filament protein LXG PF04740.12 OAP59396.1 - 0.006 16.3 2.6 0.006 16.3 2.6 3.4 2 1 1 3 3 3 1 LXG domain of WXG superfamily Syntaxin_2 PF14523.6 OAP59396.1 - 0.049 14.0 17.8 0.87 10.0 7.0 3.0 2 0 0 2 2 2 0 Syntaxin-like protein NPV_P10 PF05531.12 OAP59396.1 - 0.12 12.9 13.4 5 7.7 0.1 4.4 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Nucleoporin_FG PF13634.6 OAP59396.1 - 0.15 12.9 6.6 0.38 11.6 6.6 1.6 1 0 0 1 1 1 0 Nucleoporin FG repeat region CENP-F_leu_zip PF10473.9 OAP59396.1 - 0.24 11.4 42.8 0.72 9.9 19.5 4.0 2 2 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMPIT PF07851.13 OAP59396.1 - 1.8 7.7 18.1 0.65 9.2 5.1 2.6 2 1 0 2 2 2 0 TMPIT-like protein DUF1664 PF07889.12 OAP59396.1 - 1.8 8.6 19.4 0.35 10.9 4.7 4.0 2 2 2 4 4 4 0 Protein of unknown function (DUF1664) Csm1_N PF18504.1 OAP59396.1 - 3 8.3 18.9 8.7 6.8 0.5 4.6 2 2 1 4 4 4 0 Csm1 N-terminal domain GAS PF13851.6 OAP59396.1 - 3.8 6.8 35.8 0.58 9.5 8.0 3.5 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding KxDL PF10241.9 OAP59396.1 - 6 7.2 23.6 5.8 7.3 1.7 4.5 2 1 2 4 4 4 0 Uncharacterized conserved protein Pex14_N PF04695.13 OAP59397.1 - 2.4e-40 138.8 0.1 2.4e-40 138.8 0.1 3.4 3 1 1 4 4 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1043 PF06295.12 OAP59397.1 - 0.0099 15.9 1.4 0.02 14.9 1.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1043) FlgN PF05130.12 OAP59397.1 - 0.014 15.9 9.1 0.023 15.2 9.1 1.2 1 0 0 1 1 1 0 FlgN protein OmpH PF03938.14 OAP59397.1 - 0.02 15.3 2.8 0.02 15.3 2.8 1.7 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) zf-C4H2 PF10146.9 OAP59397.1 - 0.036 14.4 3.1 0.078 13.3 3.1 1.7 1 1 0 1 1 1 0 Zinc finger-containing protein Golgin_A5 PF09787.9 OAP59397.1 - 0.063 12.7 4.1 0.092 12.2 4.1 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 Rsd_AlgQ PF04353.13 OAP59397.1 - 0.068 13.1 0.8 0.11 12.4 0.6 1.4 1 1 0 1 1 1 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ DUF3584 PF12128.8 OAP59397.1 - 0.068 10.7 10.5 0.09 10.3 10.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Baculo_PEP_C PF04513.12 OAP59397.1 - 0.075 13.1 4.6 0.21 11.6 4.6 1.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Flagellar_rod PF05149.12 OAP59397.1 - 0.26 10.7 4.5 0.38 10.2 4.5 1.1 1 0 0 1 1 1 0 Paraflagellar rod protein FliD_N PF02465.18 OAP59397.1 - 0.28 11.9 2.8 2.6 8.8 2.8 2.6 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus HXXSHH PF07586.11 OAP59397.1 - 0.39 10.3 2.6 0.63 9.6 2.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) FAM76 PF16046.5 OAP59397.1 - 0.68 9.2 2.8 1 8.7 2.8 1.2 1 0 0 1 1 1 0 FAM76 protein DUF1451 PF07295.11 OAP59397.1 - 0.96 9.5 3.0 1.5 8.8 3.0 1.2 1 0 0 1 1 1 0 Zinc-ribbon containing domain CLZ PF16526.5 OAP59397.1 - 0.98 9.8 7.9 4.2 7.8 1.7 2.6 2 1 1 3 3 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels AAA_13 PF13166.6 OAP59397.1 - 1.3 7.6 5.3 1.7 7.2 5.3 1.1 1 0 0 1 1 1 0 AAA domain DUF4404 PF14357.6 OAP59397.1 - 2.1 9.0 7.2 0.95 10.1 4.0 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF4404) Nup88 PF10168.9 OAP59397.1 - 2.3 5.9 4.6 3.5 5.3 4.6 1.2 1 0 0 1 1 1 0 Nuclear pore component XhlA PF10779.9 OAP59397.1 - 7.3 6.9 9.9 6.6 7.0 0.5 2.8 2 1 0 3 3 3 0 Haemolysin XhlA TTL PF03133.15 OAP59399.1 - 9.8e-54 182.5 0.0 1.5e-53 181.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family SurE PF01975.17 OAP59399.1 - 3.7e-52 177.0 0.0 5.4e-52 176.4 0.0 1.2 1 0 0 1 1 1 1 Survival protein SurE ATPgrasp_YheCD PF14398.6 OAP59399.1 - 5.2e-05 22.6 0.0 0.00055 19.3 0.0 2.1 2 0 0 2 2 2 1 YheC/D like ATP-grasp ABC_tran PF00005.27 OAP59400.1 - 4.2e-33 114.8 0.0 1.2e-32 113.3 0.0 1.8 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 OAP59400.1 - 1.6e-22 80.4 7.3 2.8e-22 79.7 7.3 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 OAP59400.1 - 0.00091 18.7 0.1 0.014 14.9 0.3 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 OAP59400.1 - 0.0051 17.1 0.2 0.034 14.4 0.0 2.4 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 OAP59400.1 - 0.014 14.7 0.0 0.032 13.5 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_10 PF12846.7 OAP59400.1 - 0.028 13.4 0.3 0.067 12.1 0.0 1.7 2 0 0 2 2 2 0 AAA-like domain AAA_16 PF13191.6 OAP59400.1 - 0.051 14.0 0.1 0.33 11.3 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain RsgA_GTPase PF03193.16 OAP59400.1 - 0.059 13.3 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 OAP59400.1 - 0.1 12.4 0.2 0.35 10.7 0.2 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain MFS_1 PF07690.16 OAP59401.1 - 9.8e-23 80.6 48.2 2.4e-13 49.8 22.2 2.0 1 1 0 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.25 OAP59405.1 - 2.1e-68 230.5 0.0 2.8e-68 230.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP59405.1 - 2.1e-32 112.5 0.0 4.1e-32 111.5 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAP59405.1 - 0.00013 21.4 0.0 0.00077 18.9 0.0 2.1 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 OAP59405.1 - 0.00071 19.0 0.0 0.0012 18.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OAP59405.1 - 0.0008 19.4 0.0 0.0087 16.0 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 OAP59405.1 - 0.0092 15.6 0.0 2.5 7.7 0.0 2.3 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 OAP59405.1 - 0.027 13.4 0.0 0.042 12.8 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain PH_3 PF14593.6 OAP59405.1 - 0.069 13.3 0.0 0.22 11.6 0.0 1.8 1 0 0 1 1 1 0 PH domain MFS_1 PF07690.16 OAP59407.1 - 2.5e-38 131.9 33.4 3.1e-38 131.6 23.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAP59407.1 - 1.1e-07 31.1 11.1 1.1e-07 31.1 11.1 2.6 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 OAP59407.1 - 4.3e-07 28.7 3.0 6.3e-07 28.2 3.0 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Fungal_trans PF04082.18 OAP59408.1 - 1.8e-23 83.0 0.0 3.1e-23 82.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP59408.1 - 2.5e-07 30.7 10.9 4.6e-07 29.8 10.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.25 OAP59409.1 - 6e-42 143.3 0.0 8.1e-42 142.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP59409.1 - 6.8e-27 94.5 0.1 8.3e-27 94.2 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP59409.1 - 1.1e-05 25.5 0.0 1.7e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 OAP59409.1 - 0.00032 20.6 0.0 0.00046 20.1 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding ADH_zinc_N PF00107.26 OAP59409.1 - 0.056 13.4 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Linocin_M18 PF04454.12 OAP59409.1 - 0.069 12.4 0.0 0.16 11.3 0.0 1.5 2 0 0 2 2 2 0 Encapsulating protein for peroxidase DUF1776 PF08643.10 OAP59409.1 - 0.072 12.4 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) MgtC PF02308.16 OAP59411.1 - 0.0065 16.8 3.1 0.012 16.0 3.1 1.4 1 0 0 1 1 1 1 MgtC family DUF3278 PF11683.8 OAP59411.1 - 0.023 14.8 1.6 0.043 13.9 1.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3278) Tmpp129 PF10272.9 OAP59411.1 - 0.09 12.1 1.1 0.13 11.5 1.1 1.2 1 0 0 1 1 1 0 Putative transmembrane protein precursor DUF1670 PF07900.11 OAP59411.1 - 0.11 11.8 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1670) Peptidase_U4 PF03419.13 OAP59411.1 - 7.5 5.7 8.5 11 5.2 8.5 1.2 1 0 0 1 1 1 0 Sporulation factor SpoIIGA Asp_protease_2 PF13650.6 OAP59412.1 - 1.2e-05 25.9 0.0 2.5e-05 24.8 0.0 1.5 1 1 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 OAP59412.1 - 0.0009 19.8 0.0 0.0018 18.8 0.0 1.5 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 OAP59412.1 - 0.01 16.1 0.0 0.017 15.4 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease adh_short_C2 PF13561.6 OAP59414.1 - 6.9e-58 196.0 0.2 8.4e-58 195.7 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP59414.1 - 5.1e-48 163.1 0.6 5.9e-48 162.9 0.6 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAP59414.1 - 2.7e-13 50.2 0.4 3.9e-13 49.7 0.4 1.3 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 OAP59415.1 - 1.7e-29 102.7 0.0 2.4e-29 102.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP59415.1 - 1.5e-23 83.6 0.1 2.4e-23 82.9 0.1 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP59415.1 - 2.1e-08 34.3 0.5 1.2e-07 31.8 0.5 1.9 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 OAP59415.1 - 0.00018 21.5 0.0 0.00034 20.6 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAP59415.1 - 0.0002 20.9 0.0 0.00031 20.3 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 OAP59415.1 - 0.031 13.4 0.0 0.041 13.0 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein LytR_C PF13399.6 OAP59415.1 - 0.093 13.7 1.0 0.53 11.3 0.2 2.4 3 0 0 3 3 3 0 LytR cell envelope-related transcriptional attenuator GMC_oxred_N PF00732.19 OAP59416.1 - 5.9e-49 167.0 0.0 8.3e-49 166.6 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAP59416.1 - 1.3e-32 113.3 0.2 2.2e-32 112.5 0.2 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 OAP59416.1 - 2.3e-05 24.5 0.0 6.6e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAP59416.1 - 9.2e-05 22.2 2.6 0.0017 18.0 2.6 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAP59416.1 - 0.013 14.7 0.0 0.044 13.0 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OAP59416.1 - 0.021 13.9 0.0 0.046 12.8 0.0 1.6 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 OAP59416.1 - 0.027 13.7 0.1 6.6 5.9 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAP59416.1 - 0.13 12.2 0.0 0.29 11.1 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding SLATT_fungal PF18142.1 OAP59417.1 - 7.7e-31 106.6 0.3 9.7e-31 106.2 0.3 1.1 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain SLATT_1 PF18181.1 OAP59417.1 - 0.012 15.5 0.9 0.017 15.0 0.9 1.2 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 1 SLATT_3 PF18184.1 OAP59417.1 - 0.052 13.7 1.6 0.097 12.8 1.6 1.6 1 1 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 3 Pex14_N PF04695.13 OAP59417.1 - 3.3 8.4 9.7 1.3 9.7 1.4 2.5 2 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region NmrA PF05368.13 OAP59418.1 - 8.8e-53 179.2 0.1 1.1e-52 178.9 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAP59418.1 - 1.2e-15 57.9 1.0 1.7e-15 57.4 1.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 OAP59418.1 - 1e-05 24.7 0.0 1.4e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 OAP59418.1 - 0.00032 20.3 0.1 0.0006 19.4 0.1 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 OAP59418.1 - 0.011 16.0 0.2 0.02 15.1 0.2 1.6 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Kinesin PF00225.23 OAP59419.1 - 7.8e-58 196.0 0.0 1.3e-57 195.3 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 OAP59419.1 - 1.4e-12 47.8 0.0 4.7e-10 39.6 0.0 2.4 2 0 0 2 2 2 2 Microtubule binding Peptidase_C58 PF03543.14 OAP59419.1 - 0.099 12.3 0.0 0.4 10.4 0.0 2.0 2 0 0 2 2 2 0 Yersinia/Haemophilus virulence surface antigen GIT_CC PF16559.5 OAP59419.1 - 0.11 12.4 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF87 PF01935.17 OAP59419.1 - 0.69 10.0 3.7 7.4 6.6 0.7 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain DUF1640 PF07798.11 OAP59419.1 - 5.1 7.1 13.1 2 8.5 5.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) DASH_Spc19 PF08287.11 OAP59419.1 - 5.4 6.9 10.0 0.98 9.3 1.1 2.5 2 0 0 2 2 2 0 Spc19 Rho_Binding PF08912.11 OAP59419.1 - 9.3 7.1 10.6 0.55 11.1 0.3 2.6 2 0 0 2 2 2 0 Rho Binding Cep57_CLD_2 PF14197.6 OAP59419.1 - 10 6.3 11.0 0.48 10.6 1.1 3.4 3 1 1 4 4 4 0 Centrosome localisation domain of PPC89 Amidohydro_2 PF04909.14 OAP59421.1 - 8.1e-45 153.8 0.1 9.7e-45 153.6 0.1 1.0 1 0 0 1 1 1 1 Amidohydrolase Lactamase_B_2 PF12706.7 OAP59422.1 - 6e-32 110.8 0.0 2.7e-31 108.7 0.0 1.9 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 OAP59422.1 - 2e-13 50.6 0.1 3.2e-13 49.9 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 OAP59422.1 - 0.0071 16.4 0.0 0.12 12.4 0.0 2.3 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily adh_short PF00106.25 OAP59423.1 - 4.8e-18 65.3 0.0 9.5e-16 57.8 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAP59423.1 - 1.2e-09 38.1 0.0 4.5e-09 36.2 0.0 1.8 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP59423.1 - 0.00045 20.2 0.0 0.00067 19.6 0.0 1.2 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 OAP59423.1 - 0.022 14.2 0.1 0.32 10.4 0.0 2.0 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase DUF3292 PF11696.8 OAP59424.1 - 1.4e-267 889.4 0.0 1.6e-267 889.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3292) PRT_C PF08372.10 OAP59424.1 - 0.00022 21.0 0.1 0.00083 19.1 0.1 1.8 2 0 0 2 2 2 1 Plant phosphoribosyltransferase C-terminal DUF3433 PF11915.8 OAP59425.1 - 1.7e-35 121.3 10.5 8.4e-20 71.0 2.9 4.1 5 0 0 5 5 5 2 Protein of unknown function (DUF3433) DUF3290 PF11694.8 OAP59425.1 - 0.35 10.8 2.5 0.24 11.4 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3290) Presenilin PF01080.17 OAP59425.1 - 1.6 7.4 5.5 4.3 6.0 0.1 2.3 2 0 0 2 2 2 0 Presenilin Peptidase_S24 PF00717.23 OAP59426.1 - 7.2e-08 32.3 0.0 1.1e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like SLT PF01464.20 OAP59427.1 - 0.0053 16.4 0.0 0.0089 15.7 0.0 1.4 1 0 0 1 1 1 1 Transglycosylase SLT domain DUF3425 PF11905.8 OAP59428.1 - 1.1e-11 44.7 0.0 2.2e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) CorA PF01544.18 OAP59430.1 - 4.8e-07 29.4 3.3 1.7e-06 27.6 0.4 2.2 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein BatD PF13584.6 OAP59430.1 - 0.036 12.9 0.0 0.053 12.3 0.0 1.2 1 0 0 1 1 1 0 Oxygen tolerance Acetyltransf_2 PF00797.17 OAP59431.1 - 5.5e-37 127.8 0.0 7.6e-37 127.4 0.0 1.2 1 0 0 1 1 1 1 N-acetyltransferase adh_short PF00106.25 OAP59432.1 - 2.4e-10 40.2 0.0 6.3e-07 29.0 0.0 2.5 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAP59432.1 - 3.7e-08 33.2 0.0 0.0025 17.4 0.0 2.6 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Band_7 PF01145.25 OAP59433.1 - 7.5e-28 97.7 2.4 7.5e-28 97.7 2.4 1.5 2 0 0 2 2 2 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 OAP59433.1 - 0.038 13.7 0.5 0.067 12.9 0.1 1.6 2 0 0 2 2 2 0 SPFH domain-Band 7 family adh_short PF00106.25 OAP59434.1 - 5.1e-29 101.1 0.0 2.2e-27 95.8 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP59434.1 - 1.4e-18 67.3 0.0 1.2e-17 64.3 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP59434.1 - 9e-06 25.7 0.1 1.4e-05 25.1 0.1 1.2 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.20 OAP59434.1 - 0.13 12.3 0.2 0.23 11.5 0.2 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase p450 PF00067.22 OAP59435.1 - 3.3e-54 184.4 0.0 5e-54 183.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 UQ_con PF00179.26 OAP59435.1 - 2.4e-21 75.9 0.0 4.7e-21 74.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme EAF PF09816.9 OAP59436.1 - 2.4e-13 50.3 0.0 4.8e-13 49.4 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor DUF726 PF05277.12 OAP59437.1 - 3.5e-120 401.0 1.3 4.9e-120 400.6 1.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Trypan_PARP PF05887.11 OAP59437.1 - 0.0044 17.0 15.0 0.013 15.4 15.0 1.9 1 1 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) Abhydrolase_6 PF12697.7 OAP59437.1 - 0.015 15.9 1.1 0.015 15.9 1.1 2.8 2 1 0 3 3 3 0 Alpha/beta hydrolase family SPESP1 PF15754.5 OAP59437.1 - 0.024 13.8 1.5 0.046 12.9 1.5 1.4 1 0 0 1 1 1 0 Sperm equatorial segment protein 1 Thioesterase PF00975.20 OAP59437.1 - 0.075 13.1 0.5 0.16 12.0 0.0 1.7 2 0 0 2 2 2 0 Thioesterase domain TonB_N PF16031.5 OAP59437.1 - 0.41 11.2 14.9 0.27 11.7 12.6 1.9 1 1 0 1 1 1 0 TonB polyproline region Rav1p_C PF12234.8 OAP59438.1 - 6.3e-192 639.4 0.0 1e-191 638.7 0.0 1.3 1 0 0 1 1 1 1 RAVE protein 1 C terminal WD40 PF00400.32 OAP59438.1 - 0.32 11.9 15.7 5.2 8.1 0.0 6.7 8 0 0 8 8 8 0 WD domain, G-beta repeat Peptidase_C12 PF01088.21 OAP59439.1 - 1.1e-42 146.2 0.0 1.3e-42 145.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 PhyH PF05721.13 OAP59440.1 - 3.5e-18 66.6 0.0 1.2e-17 64.9 0.0 1.8 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 OAP59440.1 - 0.19 10.4 0.0 0.97 8.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1479) AAA_24 PF13479.6 OAP59441.1 - 0.014 15.2 0.2 3.6 7.3 0.1 2.2 2 0 0 2 2 2 0 AAA domain DUF4096 PF13340.6 OAP59441.1 - 0.064 13.5 0.8 17 5.7 0.1 2.5 2 0 0 2 2 2 0 Putative transposase of IS4/5 family (DUF4096) EFTUD2 PF16004.5 OAP59441.1 - 0.65 10.6 15.1 0.49 11.0 4.1 2.5 3 0 0 3 3 3 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus DUF3328 PF11807.8 OAP59442.1 - 3.3e-43 148.0 0.0 3.9e-43 147.8 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.8 OAP59443.1 - 1.1e-13 51.5 0.0 1.7e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) RIBIOP_C PF04950.12 OAP59444.1 - 7.1e-96 321.1 0.0 7.1e-96 321.1 0.0 2.1 2 0 0 2 2 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 OAP59444.1 - 9.9e-29 99.3 0.0 3.6e-28 97.5 0.0 2.1 1 0 0 1 1 1 1 AARP2CN (NUC121) domain AAA_22 PF13401.6 OAP59444.1 - 4.5e-05 23.7 0.2 0.00018 21.8 0.0 2.1 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.6 OAP59444.1 - 0.00032 21.1 0.0 0.0014 19.0 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 OAP59444.1 - 0.00032 20.9 0.0 0.0011 19.1 0.0 2.0 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 OAP59444.1 - 0.00055 20.0 0.0 0.0019 18.2 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OAP59444.1 - 0.00056 19.5 0.0 0.072 12.6 0.0 2.5 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA PF00004.29 OAP59444.1 - 0.00075 19.9 0.0 0.0022 18.4 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 OAP59444.1 - 0.00079 19.4 0.0 0.0016 18.4 0.0 1.6 1 0 0 1 1 1 1 NACHT domain ABC_tran PF00005.27 OAP59444.1 - 0.0028 18.2 0.7 0.0098 16.4 0.0 2.2 2 0 0 2 2 1 1 ABC transporter AAA_19 PF13245.6 OAP59444.1 - 0.0038 17.6 0.0 0.0091 16.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 OAP59444.1 - 0.01 15.0 0.0 0.021 14.0 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain PduV-EutP PF10662.9 OAP59444.1 - 0.012 15.4 0.0 0.093 12.5 0.0 2.1 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.22 OAP59444.1 - 0.018 15.5 0.0 0.039 14.4 0.0 1.6 1 0 0 1 1 1 0 RNA helicase cobW PF02492.19 OAP59444.1 - 0.018 14.6 0.1 0.036 13.6 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 OAP59444.1 - 0.023 14.6 0.0 0.1 12.5 0.0 2.0 2 0 0 2 2 1 0 RsgA GTPase AAA_7 PF12775.7 OAP59444.1 - 0.025 14.1 0.1 0.077 12.5 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region ATPase_2 PF01637.18 OAP59444.1 - 0.029 14.3 0.9 0.079 12.9 0.0 2.1 2 0 0 2 2 1 0 ATPase domain predominantly from Archaea MobB PF03205.14 OAP59444.1 - 0.032 14.1 0.4 0.39 10.6 0.0 2.8 2 1 1 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 OAP59444.1 - 0.036 14.0 0.1 0.067 13.1 0.1 1.4 1 0 0 1 1 1 0 NTPase KAP_NTPase PF07693.14 OAP59444.1 - 0.037 13.3 0.0 0.077 12.2 0.0 1.5 1 0 0 1 1 1 0 KAP family P-loop domain AAA_24 PF13479.6 OAP59444.1 - 0.041 13.6 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 OAP59444.1 - 0.043 13.4 0.5 0.21 11.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 OAP59444.1 - 0.045 14.3 0.1 0.045 14.3 0.1 3.0 3 0 0 3 3 2 0 AAA domain AAA_5 PF07728.14 OAP59444.1 - 0.082 12.9 0.1 0.28 11.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Roc PF08477.13 OAP59444.1 - 0.095 12.9 0.0 0.26 11.5 0.0 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_14 PF13173.6 OAP59444.1 - 0.1 12.6 0.0 0.33 11.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 OAP59444.1 - 0.2 11.4 0.0 0.2 11.4 0.0 3.2 3 1 0 3 3 2 0 AAA domain FeoB_N PF02421.18 OAP59444.1 - 0.21 11.1 0.0 0.84 9.1 0.0 2.0 2 0 0 2 2 2 0 Ferrous iron transport protein B Whi5 PF08528.11 OAP59445.1 - 2.6e-11 42.9 0.2 4.8e-11 42.0 0.2 1.5 1 0 0 1 1 1 1 Whi5 like DUF4578 PF15147.6 OAP59445.1 - 6.4 7.7 10.5 15 6.5 0.2 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4578) adh_short_C2 PF13561.6 OAP59446.1 - 8.4e-54 182.6 3.4 2e-48 165.0 0.6 2.6 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP59446.1 - 4.8e-44 150.2 0.2 1.2e-34 119.5 0.0 2.4 1 1 1 2 2 2 2 short chain dehydrogenase Epimerase PF01370.21 OAP59446.1 - 6.2e-05 22.6 0.0 0.0032 17.0 0.0 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DFP PF04127.15 OAP59446.1 - 0.036 13.9 0.4 0.1 12.4 0.1 1.8 1 1 1 2 2 2 0 DNA / pantothenate metabolism flavoprotein KR PF08659.10 OAP59446.1 - 0.049 13.6 2.9 0.7 9.8 0.8 3.0 2 2 0 2 2 2 0 KR domain PPO1_KFDV PF12143.8 OAP59446.1 - 0.18 11.9 0.0 0.28 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF_B2219) AAA PF00004.29 OAP59447.1 - 7.6e-17 62.0 0.1 3e-16 60.0 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 OAP59447.1 - 0.0031 17.5 0.0 0.0086 16.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 OAP59447.1 - 0.0048 17.2 0.6 0.032 14.5 0.1 2.5 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 OAP59447.1 - 0.033 14.3 0.3 0.45 10.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 OAP59447.1 - 0.051 13.3 0.0 0.15 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 OAP59447.1 - 0.072 13.5 1.1 0.35 11.2 0.9 2.2 1 1 0 1 1 1 0 AAA ATPase domain CDC27 PF09507.10 OAP59447.1 - 1.3 8.4 36.8 3.7 6.8 36.8 1.7 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 SWI-SNF_Ssr4 PF08549.10 OAP59447.1 - 4.6 5.8 18.0 7.4 5.1 18.0 1.3 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) PspB PF06667.12 OAP59448.1 - 0.029 14.4 0.3 0.052 13.6 0.3 1.4 1 0 0 1 1 1 0 Phage shock protein B ADH_zinc_N PF00107.26 OAP59449.1 - 3.5e-15 56.1 0.0 5.6e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 OAP59449.1 - 4.2e-11 42.7 0.0 9.9e-11 41.5 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 OAP59449.1 - 0.00065 20.8 0.0 0.0012 19.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase IBR PF01485.21 OAP59450.1 - 3.2e-09 36.9 54.6 9.9e-08 32.1 7.6 4.6 4 1 0 4 4 4 3 IBR domain, a half RING-finger domain Tub_N PF16322.5 OAP59450.1 - 0.23 11.9 1.8 0.42 11.0 1.8 1.4 1 0 0 1 1 1 0 Tubby N-terminal Radial_spoke PF04712.12 OAP59450.1 - 0.76 8.6 5.5 1 8.2 5.5 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein RNA_pol_3_Rpc31 PF11705.8 OAP59450.1 - 5.5 7.2 10.0 9.1 6.5 10.0 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Voldacs PF03517.13 OAP59450.1 - 6 7.0 8.2 13 5.9 8.2 1.5 1 0 0 1 1 1 0 Regulator of volume decrease after cellular swelling Ldh_1_C PF02866.18 OAP59451.1 - 1.4e-48 165.0 0.0 3e-48 163.9 0.0 1.5 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 OAP59451.1 - 8.2e-43 145.9 0.0 1.3e-42 145.3 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 OAP59451.1 - 0.00029 20.0 0.0 0.00039 19.5 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 OAP59451.1 - 0.073 13.5 0.1 0.29 11.6 0.0 2.0 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain MFS_1 PF07690.16 OAP59452.1 - 2.1e-23 82.8 23.3 2.1e-23 82.8 23.3 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 OAP59452.1 - 0.0011 17.5 2.4 0.0015 17.1 2.4 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF5326 PF17260.2 OAP59453.1 - 0.093 12.9 0.1 0.093 12.9 0.1 2.9 3 1 0 3 3 3 0 Family of unknown function (DUF5326) DUF2964 PF11177.8 OAP59453.1 - 1.3 9.3 4.5 1.7 8.9 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2964) UCH PF00443.29 OAP59454.1 - 8.2e-74 248.3 0.0 1.7e-73 247.3 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase PX PF00787.24 OAP59454.1 - 2e-16 60.0 0.0 6.7e-16 58.3 0.0 1.9 1 0 0 1 1 1 1 PX domain DUSP PF06337.12 OAP59454.1 - 2e-14 53.9 0.0 1.1e-13 51.6 0.0 2.4 1 0 0 1 1 1 1 DUSP domain UCH_1 PF13423.6 OAP59454.1 - 8.8e-13 48.5 0.7 3.2e-05 23.7 0.0 3.6 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Vps5 PF09325.10 OAP59454.1 - 1.4e-06 28.0 7.4 1e-05 25.2 0.4 2.3 2 0 0 2 2 2 2 Vps5 C terminal like Shisa PF13908.6 OAP59454.1 - 3.8 7.7 0.0 3.8 7.7 0.0 3.1 3 0 0 3 3 3 0 Wnt and FGF inhibitory regulator DUF2428 PF10350.9 OAP59455.1 - 3.1e-50 171.0 2.0 7.9e-50 169.6 2.0 1.7 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) HEAT_2 PF13646.6 OAP59455.1 - 0.00025 21.4 8.6 0.033 14.6 0.2 4.8 5 0 0 5 5 5 2 HEAT repeats HEAT PF02985.22 OAP59455.1 - 0.0004 20.4 7.6 20 5.8 0.1 7.0 6 0 0 6 6 6 2 HEAT repeat RTP1_C1 PF10363.9 OAP59455.1 - 0.02 15.1 0.2 3.3 7.9 0.1 3.9 3 1 1 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 Cnd1 PF12717.7 OAP59455.1 - 0.1 12.6 0.9 6.3 6.8 0.1 3.3 4 0 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 Tim17 PF02466.19 OAP59456.1 - 3.9e-28 98.1 3.2 6.3e-28 97.4 3.2 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family NAD_binding_10 PF13460.6 OAP59457.1 - 3.3e-11 43.4 0.0 3.7e-10 40.0 0.0 2.5 1 1 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 OAP59457.1 - 1e-06 28.0 0.0 8.1e-06 25.0 0.0 2.0 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 OAP59457.1 - 3.3e-06 26.7 0.0 1.3e-05 24.8 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 OAP59457.1 - 0.0012 18.0 0.1 0.06 12.4 0.0 2.9 2 1 1 3 3 3 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 OAP59457.1 - 0.0041 16.3 0.0 0.038 13.1 0.0 2.2 2 0 0 2 2 2 1 Male sterility protein GDP_Man_Dehyd PF16363.5 OAP59457.1 - 0.032 13.6 0.0 0.046 13.1 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase adh_short PF00106.25 OAP59457.1 - 0.044 13.2 0.0 0.13 11.7 0.0 1.8 2 0 0 2 2 2 0 short chain dehydrogenase SYF2 PF08231.12 OAP59458.1 - 7.4e-48 163.0 15.6 7.4e-48 163.0 15.6 1.9 2 1 0 2 2 2 1 SYF2 splicing factor TetR_C_24 PF17932.1 OAP59458.1 - 0.021 15.1 1.3 0.16 12.2 0.2 2.6 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain DAO PF01266.24 OAP59459.1 - 4.2e-29 102.2 0.1 5.8e-29 101.8 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAP59459.1 - 0.0011 19.2 0.1 0.0031 17.7 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAP59459.1 - 0.0017 17.6 0.0 0.0037 16.6 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Sacchrp_dh_NADP PF03435.18 OAP59459.1 - 0.0019 18.5 0.1 0.011 16.0 0.0 2.0 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain FAD_binding_3 PF01494.19 OAP59459.1 - 0.035 13.4 0.0 0.055 12.7 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.14 OAP59459.1 - 0.071 11.9 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Thi4 PF01946.17 OAP59459.1 - 0.14 11.4 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.27 OAP59459.1 - 0.15 12.6 0.0 0.46 11.1 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase YEATS PF03366.16 OAP59460.1 - 3.1e-35 120.0 1.5 4.9e-35 119.4 1.5 1.3 1 0 0 1 1 1 1 YEATS family V-set_2 PF15910.5 OAP59460.1 - 0.19 11.8 0.0 2.8 8.1 0.0 2.1 2 0 0 2 2 2 0 ICOS V-set domain M16C_assoc PF08367.11 OAP59460.1 - 0.78 8.8 3.3 1.3 8.1 3.3 1.2 1 0 0 1 1 1 0 Peptidase M16C associated Velvet PF11754.8 OAP59462.1 - 2.9e-42 145.3 2.1 9.6e-23 81.4 0.0 2.7 2 1 1 3 3 3 2 Velvet factor Glyoxalase PF00903.25 OAP59463.1 - 3.9e-09 36.8 0.0 7.8e-09 35.8 0.0 1.5 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 OAP59463.1 - 1.6e-06 28.3 0.1 2e-06 28.1 0.1 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 OAP59463.1 - 0.00099 19.0 0.0 0.0065 16.4 0.0 2.0 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_6 PF18029.1 OAP59463.1 - 0.0017 19.1 0.0 0.0043 17.8 0.0 1.6 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_3 PF13468.6 OAP59463.1 - 0.011 15.9 0.2 0.016 15.4 0.2 1.5 1 1 0 1 1 1 0 Glyoxalase-like domain Lipase_3 PF01764.25 OAP59465.1 - 3.5e-19 69.1 0.0 9.4e-19 67.7 0.0 1.7 2 0 0 2 2 2 1 Lipase (class 3) Abhydrolase_6 PF12697.7 OAP59465.1 - 0.0034 18.0 0.2 0.0034 18.0 0.2 2.4 2 1 0 2 2 2 1 Alpha/beta hydrolase family TGBp3 PF02495.17 OAP59465.1 - 0.098 12.3 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Triple gene block 3 PGAP1 PF07819.13 OAP59465.1 - 0.16 11.6 0.0 0.37 10.5 0.0 1.5 2 0 0 2 2 2 0 PGAP1-like protein Transp_cyt_pur PF02133.15 OAP59468.1 - 1.1e-75 255.1 32.8 1.4e-75 254.8 32.8 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Amidase PF01425.21 OAP59469.1 - 3e-73 247.3 0.0 3.7e-73 247.0 0.0 1.1 1 0 0 1 1 1 1 Amidase Isochorismatase PF00857.20 OAP59469.1 - 8.1e-35 120.6 0.0 3.2e-34 118.6 0.0 1.9 2 0 0 2 2 2 1 Isochorismatase family Ovate PF04844.13 OAP59469.1 - 0.13 12.2 0.0 0.36 10.8 0.0 1.7 1 0 0 1 1 1 0 Transcriptional repressor, ovate Fungal_trans PF04082.18 OAP59470.1 - 1.9e-23 82.8 0.1 1.9e-23 82.8 0.1 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP59470.1 - 0.0065 16.6 8.3 0.012 15.7 8.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 OAP59471.1 - 3.1e-21 75.7 67.3 9.1e-12 44.6 32.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF5056 PF16479.5 OAP59471.1 - 0.076 13.2 0.9 1 9.6 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5056) DUF5368 PF17336.2 OAP59471.1 - 4.9 7.4 10.9 0.32 11.2 1.4 3.3 3 0 0 3 3 3 0 Family of unknown function (DUF5368) Beta-lactamase PF00144.24 OAP59472.1 - 4.1e-57 193.9 0.0 5.2e-57 193.6 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase Fungal_trans_2 PF11951.8 OAP59474.1 - 0.025 13.4 0.3 0.025 13.4 0.3 2.4 3 0 0 3 3 3 0 Fungal specific transcription factor domain Atg8 PF02991.16 OAP59475.1 - 9.7e-51 170.3 0.2 1.1e-50 170.1 0.2 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 OAP59475.1 - 3.7e-06 27.2 0.0 4.5e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Coprogen_oxidas PF01218.18 OAP59476.1 - 1.6e-136 453.8 0.0 2e-136 453.6 0.0 1.1 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase Cu-oxidase_3 PF07732.15 OAP59477.1 - 1.8e-42 144.1 10.5 1.8e-41 140.9 2.8 3.6 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 OAP59477.1 - 2.8e-37 127.5 13.2 1.2e-31 109.3 2.9 4.2 3 1 0 3 3 3 3 Multicopper oxidase Cu-oxidase PF00394.22 OAP59477.1 - 1.6e-35 122.6 0.0 7.6e-33 113.9 0.0 2.5 2 0 0 2 2 2 2 Multicopper oxidase Atg29_N PF18388.1 OAP59478.1 - 3.8e-27 93.9 0.9 6.6e-27 93.1 0.9 1.4 1 0 0 1 1 1 1 Atg29 N-terminal domain Glyco_hydro_16 PF00722.21 OAP59480.1 - 1.7e-07 30.9 0.0 2.7e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 TFIIA PF03153.13 OAP59480.1 - 4.4 7.2 13.5 5.5 6.9 13.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SARAF PF06682.12 OAP59480.1 - 9.2 5.8 7.2 12 5.4 7.2 1.2 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Ferritin_2 PF13668.6 OAP59481.1 - 1.7e-17 63.9 0.0 3.1e-17 63.0 0.0 1.4 1 0 0 1 1 1 1 Ferritin-like domain Tmemb_9 PF05434.11 OAP59484.1 - 0.022 14.7 0.4 0.048 13.6 0.0 1.7 2 0 0 2 2 2 0 TMEM9 AAL_decarboxy PF03306.13 OAP59486.1 - 5.4e-78 261.3 0.3 6.1e-78 261.1 0.3 1.0 1 0 0 1 1 1 1 Alpha-acetolactate decarboxylase TPP_enzyme_N PF02776.18 OAP59487.1 - 7.2e-44 149.4 1.6 6.7e-43 146.3 2.2 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 OAP59487.1 - 2e-37 128.3 0.6 1.2e-36 125.9 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 OAP59487.1 - 1.2e-22 80.1 0.0 2.1e-22 79.3 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain DUF1194 PF06707.11 OAP59487.1 - 0.05 12.8 0.0 0.086 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1194) AsnC_trans_reg2 PF17805.1 OAP59487.1 - 0.14 12.3 0.2 2.3 8.4 0.0 2.5 2 0 0 2 2 2 0 AsnC-like ligand binding domain Zn_clus PF00172.18 OAP59489.1 - 6.6e-08 32.6 10.6 1.6e-07 31.4 10.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Transferase PF02458.15 OAP59490.1 - 1.2e-16 60.4 0.0 1.7e-16 59.9 0.0 1.2 1 0 0 1 1 1 1 Transferase family Asp PF00026.23 OAP59491.1 - 4e-28 98.8 0.0 3.1e-13 49.8 0.0 2.0 2 0 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 OAP59491.1 - 0.0011 19.2 0.5 0.94 9.7 0.1 2.8 3 0 0 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 OAP59491.1 - 0.009 16.6 0.3 13 6.5 0.0 3.1 3 0 0 3 3 3 2 Aspartyl protease TAXi_C PF14541.6 OAP59491.1 - 0.11 12.3 0.0 0.3 10.8 0.0 1.7 1 1 1 2 2 2 0 Xylanase inhibitor C-terminal Mob1_phocein PF03637.17 OAP59492.1 - 1.3e-45 155.5 0.0 2.9e-45 154.3 0.0 1.6 1 1 0 1 1 1 1 Mob1/phocein family FAM220 PF15487.6 OAP59492.1 - 0.13 11.9 0.5 0.19 11.3 0.5 1.2 1 0 0 1 1 1 0 FAM220 family Leo1 PF04004.13 OAP59493.1 - 8e-32 110.4 0.1 1.8e-31 109.2 0.1 1.6 1 0 0 1 1 1 1 Leo1-like protein BAH PF01426.18 OAP59494.1 - 6.7e-18 64.7 0.0 1.6e-17 63.5 0.0 1.7 1 0 0 1 1 1 1 BAH domain zf-HC5HC2H_2 PF13832.6 OAP59494.1 - 8.8e-17 61.3 0.2 8.8e-17 61.3 0.2 3.9 3 1 0 3 3 3 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 OAP59494.1 - 6.9e-14 51.9 0.3 6.9e-14 51.9 0.3 4.4 4 1 0 4 4 4 2 PHD-like zinc-binding domain PHD PF00628.29 OAP59494.1 - 3.2e-11 42.9 45.6 5.7e-07 29.3 5.0 5.8 6 0 0 6 6 6 2 PHD-finger PHD_2 PF13831.6 OAP59494.1 - 4e-09 35.9 3.3 4e-09 35.9 3.3 3.9 5 0 0 5 5 4 1 PHD-finger C1_1 PF00130.22 OAP59494.1 - 0.00052 19.9 3.5 0.00052 19.9 3.5 6.4 6 1 1 7 7 7 2 Phorbol esters/diacylglycerol binding domain (C1 domain) LsmAD PF06741.13 OAP59494.1 - 0.029 14.9 0.2 0.029 14.9 0.2 2.6 3 0 0 3 3 1 0 LsmAD domain Myb_DNA-binding PF00249.31 OAP59494.1 - 0.052 13.7 0.1 0.21 11.8 0.1 2.0 2 0 0 2 2 2 0 Myb-like DNA-binding domain DNA_primase_lrg PF04104.14 OAP59494.1 - 0.053 12.9 0.7 0.14 11.5 0.7 1.7 1 0 0 1 1 1 0 Eukaryotic and archaeal DNA primase, large subunit TrkA_C PF02080.21 OAP59494.1 - 0.2 11.5 0.0 0.5 10.2 0.0 1.6 1 0 0 1 1 1 0 TrkA-C domain Siva PF05458.12 OAP59494.1 - 0.31 10.7 7.2 4.4 7.0 0.2 2.8 2 0 0 2 2 2 0 Cd27 binding protein (Siva) DEAD PF00270.29 OAP59495.1 - 5.8e-15 55.5 0.0 2.4e-14 53.5 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAP59495.1 - 5.2e-07 30.0 0.0 4.1e-06 27.1 0.0 2.3 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAP59495.1 - 1.3e-06 28.5 0.0 2.2e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF4332 PF14229.6 OAP59495.1 - 0.0078 16.5 0.1 0.024 14.9 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4332) AAA_5 PF07728.14 OAP59495.1 - 0.09 12.8 0.0 0.34 10.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) HHH_5 PF14520.6 OAP59495.1 - 0.094 13.3 0.0 0.53 10.9 0.0 2.3 2 0 0 2 2 2 0 Helix-hairpin-helix domain Zn_clus PF00172.18 OAP59496.1 - 3e-07 30.5 9.9 5.4e-07 29.6 9.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FMN_red PF03358.15 OAP59496.1 - 3.6e-07 30.0 0.0 7.2e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_1 PF00258.25 OAP59496.1 - 0.0058 16.9 0.3 0.013 15.7 0.3 1.6 1 1 0 1 1 1 1 Flavodoxin APH PF01636.23 OAP59497.1 - 1.3e-37 130.0 0.0 2e-37 129.4 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 OAP59497.1 - 8e-05 22.3 0.0 0.17 11.5 0.1 2.3 2 0 0 2 2 2 2 RIO1 family EcKinase PF02958.20 OAP59497.1 - 0.00011 21.6 0.0 0.0002 20.8 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase AMP-binding PF00501.28 OAP59498.1 - 3.2e-70 236.9 0.0 3.9e-70 236.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAP59498.1 - 5e-12 46.6 0.1 1.4e-11 45.2 0.0 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain MaoC_dehydratas PF01575.19 OAP59499.1 - 1.2e-26 92.7 0.0 2.9e-26 91.4 0.0 1.6 2 0 0 2 2 2 1 MaoC like domain MaoC_dehydrat_N PF13452.6 OAP59499.1 - 1.4e-09 38.2 0.1 0.0004 20.5 0.1 2.5 2 1 0 2 2 2 2 N-terminal half of MaoC dehydratase Bacteriocin_IId PF09221.10 OAP59499.1 - 0.037 14.2 0.5 0.092 12.9 0.5 1.7 1 0 0 1 1 1 0 Bacteriocin class IId cyclical uberolysin-like ECH_1 PF00378.20 OAP59500.1 - 8.7e-37 126.8 0.0 1e-36 126.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAP59500.1 - 2.7e-17 63.3 0.0 3.2e-17 63.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase DEAD PF00270.29 OAP59501.1 - 1.1e-52 178.4 0.0 2.1e-52 177.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAP59501.1 - 1.6e-33 115.3 0.6 3.5e-29 101.4 0.1 2.6 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.15 OAP59501.1 - 9.7e-09 35.5 0.0 2.1e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 OAP59501.1 - 1.5e-06 27.6 0.2 2.4e-05 23.7 0.1 2.2 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_RecD PF05127.14 OAP59501.1 - 0.0088 15.9 0.2 0.023 14.6 0.0 1.8 2 0 0 2 2 2 1 Helicase AAA_30 PF13604.6 OAP59501.1 - 0.0096 15.6 0.0 0.02 14.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain UTP25 PF06862.12 OAP59501.1 - 0.032 13.0 0.1 0.93 8.2 0.0 2.2 2 0 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 CMS1 PF14617.6 OAP59501.1 - 0.19 11.0 3.7 1.7 8.0 0.0 2.5 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit Rft-1 PF04506.13 OAP59502.1 - 1.5e-129 433.1 7.5 1.8e-129 432.8 7.5 1.0 1 0 0 1 1 1 1 Rft protein Polysacc_synt PF01943.17 OAP59502.1 - 4.9e-05 22.8 8.9 4.9e-05 22.8 8.9 2.4 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein Proteasome PF00227.26 OAP59503.1 - 3.3e-45 153.9 0.1 4.6e-45 153.4 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 OAP59503.1 - 3.2e-15 55.2 3.0 3.2e-15 55.2 3.0 1.8 2 0 0 2 2 2 1 Proteasome beta subunits C terminal Sugar_tr PF00083.24 OAP59504.1 - 1.4e-80 271.4 22.6 1.6e-80 271.2 22.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP59504.1 - 5.4e-27 94.6 60.4 3.5e-21 75.5 30.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily NUP214 PF16755.5 OAP59505.1 - 3.6e-13 49.5 0.0 1.4e-12 47.6 0.0 1.9 1 1 0 1 1 1 1 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 ANAPC4_WD40 PF12894.7 OAP59505.1 - 0.0017 18.6 0.0 0.026 14.8 0.0 2.6 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain DUF1664 PF07889.12 OAP59505.1 - 0.83 9.7 3.8 4.4 7.4 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) KH_1 PF00013.29 OAP59506.1 - 3.8e-42 141.9 3.9 8e-18 64.0 0.2 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 OAP59506.1 - 9e-11 41.4 0.8 0.0097 15.7 0.2 3.2 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 OAP59506.1 - 2.7e-05 24.1 6.7 0.22 11.7 0.1 3.3 3 0 0 3 3 3 3 NusA-like KH domain KH_4 PF13083.6 OAP59506.1 - 8.9e-05 22.3 0.1 0.77 9.7 0.0 3.2 3 0 0 3 3 3 2 KH domain MOEP19 PF16005.5 OAP59506.1 - 0.00033 20.6 0.0 0.049 13.6 0.0 2.3 2 0 0 2 2 2 2 KH-like RNA-binding domain MltA PF03562.17 OAP59507.1 - 0.062 13.1 0.0 0.062 13.1 0.0 1.1 1 0 0 1 1 1 0 MltA specific insert domain Meth_synt_2 PF01717.18 OAP59508.1 - 5e-08 32.6 0.0 8.6e-07 28.5 0.0 2.6 1 1 0 1 1 1 1 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 OAP59508.1 - 0.016 14.8 0.0 0.027 14.0 0.0 1.4 1 0 0 1 1 1 0 Cobalamin-independent synthase, N-terminal domain Sugar_tr PF00083.24 OAP59509.1 - 1.2e-81 274.9 26.1 1.4e-81 274.7 26.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP59509.1 - 3.6e-25 88.7 24.8 1.3e-24 86.8 21.4 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily adh_short_C2 PF13561.6 OAP59511.1 - 2.2e-53 181.3 2.1 5.7e-43 147.1 1.4 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP59511.1 - 1.1e-43 149.0 2.9 1.5e-43 148.5 2.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase 3HCDH_N PF02737.18 OAP59511.1 - 0.077 12.9 1.5 0.14 12.0 0.7 1.8 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DLH PF01738.18 OAP59512.1 - 1.9e-22 79.9 0.0 2.5e-22 79.5 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Gpr1_Fun34_YaaH PF01184.19 OAP59513.1 - 1.7e-32 112.8 17.4 2.2e-32 112.4 17.4 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family IucA_IucC PF04183.12 OAP59514.1 - 0.02 14.5 0.0 4.5 6.8 0.0 2.3 1 1 1 2 2 2 0 IucA / IucC family DUF2909 PF11137.8 OAP59514.1 - 0.11 12.5 0.4 0.23 11.4 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2909) HET PF06985.11 OAP59515.1 - 0.0054 17.1 0.0 1.2 9.4 0.0 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) FeoB_Cyto PF17910.1 OAP59516.1 - 0.0031 18.0 0.0 0.0052 17.3 0.0 1.3 1 0 0 1 1 1 1 FeoB cytosolic helical domain DSPc PF00782.20 OAP59517.1 - 6.9e-09 35.6 0.0 1.3e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 OAP59517.1 - 2.2e-06 27.4 0.0 3.6e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 OAP59517.1 - 0.047 13.8 0.0 0.094 12.8 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 OAP59517.1 - 0.072 13.1 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family MFS_1 PF07690.16 OAP59518.1 - 2e-44 152.0 70.7 2.1e-41 142.0 52.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MMM1 PF10296.9 OAP59519.1 - 8.9e-129 429.3 0.0 1.2e-128 428.9 0.0 1.1 1 0 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 DUF2683 PF10884.8 OAP59519.1 - 0.11 12.8 0.0 0.25 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2683) ARD PF03079.14 OAP59521.1 - 3.3e-46 157.3 0.4 4e-46 157.1 0.4 1.1 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 OAP59521.1 - 4.8e-09 35.8 0.0 8.5e-09 35.0 0.0 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 OAP59521.1 - 7.2e-06 25.9 0.0 1.1e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain DUF4078 PF13300.6 OAP59521.1 - 0.048 14.0 1.2 2.6 8.4 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4078) adh_short PF00106.25 OAP59522.1 - 8.8e-29 100.4 0.0 1.3e-28 99.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP59522.1 - 1.8e-19 70.2 0.0 2.4e-19 69.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP59522.1 - 2.5e-08 34.1 0.0 3.7e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAP59522.1 - 3e-05 23.6 0.0 6.7e-05 22.5 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 OAP59522.1 - 0.0089 15.2 0.0 0.012 14.8 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 OAP59522.1 - 0.025 14.1 0.1 0.052 13.1 0.1 1.5 1 0 0 1 1 1 0 NmrA-like family DapB_N PF01113.20 OAP59522.1 - 0.044 13.9 0.0 0.095 12.8 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus RmlD_sub_bind PF04321.17 OAP59522.1 - 0.045 12.9 0.0 0.082 12.0 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain GCIP PF13324.6 OAP59522.1 - 8.2 5.9 6.3 16 5.0 6.3 1.4 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting BRE1 PF08647.11 OAP59523.1 - 3.1e-24 84.8 9.8 3.1e-24 84.8 9.8 6.7 5 1 1 6 6 6 1 BRE1 E3 ubiquitin ligase zf-C3HC4_2 PF13923.6 OAP59523.1 - 1.5e-09 37.5 8.1 3e-09 36.6 8.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OAP59523.1 - 1e-08 34.9 7.0 1.9e-08 34.0 7.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAP59523.1 - 1.7e-07 31.0 10.7 3.1e-07 30.1 10.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAP59523.1 - 5.2e-07 29.6 5.1 1.4e-06 28.2 5.1 1.8 1 0 0 1 1 1 1 RING-type zinc-finger APG6_N PF17675.1 OAP59523.1 - 1e-06 29.3 88.9 0.00067 20.2 0.8 6.9 2 1 5 7 7 7 3 Apg6 coiled-coil region zf-RING_2 PF13639.6 OAP59523.1 - 5.1e-06 26.7 6.9 9.2e-06 25.9 6.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 OAP59523.1 - 8.7e-06 25.6 9.8 1.6e-05 24.7 9.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 OAP59523.1 - 1.7e-05 24.6 6.8 3.2e-05 23.7 6.8 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 KxDL PF10241.9 OAP59523.1 - 0.00024 21.3 6.9 0.00024 21.3 6.9 6.7 6 1 0 6 6 6 1 Uncharacterized conserved protein DUF1272 PF06906.11 OAP59523.1 - 0.00033 20.7 5.5 0.00069 19.7 5.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1272) zf-C3HC4_4 PF15227.6 OAP59523.1 - 0.0021 18.2 6.0 0.004 17.3 6.0 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING DZR PF12773.7 OAP59523.1 - 0.0072 16.3 6.8 0.014 15.4 6.8 1.4 1 0 0 1 1 1 1 Double zinc ribbon zf-RING_10 PF16685.5 OAP59523.1 - 0.032 14.4 5.2 0.096 12.8 5.2 1.9 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_4 PF14570.6 OAP59523.1 - 0.046 13.5 5.5 0.094 12.5 5.3 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 OAP59523.1 - 0.15 12.4 7.5 0.095 13.0 4.9 2.1 2 0 0 2 2 1 0 RING-H2 zinc finger domain zf-ribbon_3 PF13248.6 OAP59523.1 - 0.18 11.3 3.4 0.41 10.1 0.9 2.4 2 0 0 2 2 2 0 zinc-ribbon domain TBD PF12845.7 OAP59523.1 - 1.3 9.0 6.7 7.9 6.5 4.0 3.1 2 0 0 2 2 2 0 TBD domain PTSIIB_sorb PF03830.15 OAP59523.1 - 1.4 9.1 7.2 3.3 7.9 0.7 3.1 2 1 0 2 2 2 0 PTS system sorbose subfamily IIB component ATG16 PF08614.11 OAP59523.1 - 2 8.6 88.0 0.23 11.6 24.1 6.1 3 1 2 5 5 5 0 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.9 OAP59523.1 - 2.7 8.0 71.7 0.92 9.5 0.6 6.7 3 1 3 6 6 6 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2218 PF09981.9 OAP59523.1 - 6 7.3 11.9 0.93 9.9 2.4 3.5 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2218) FPP PF05911.11 OAP59523.1 - 6.2 4.9 67.4 0.44 8.7 29.0 3.4 1 1 2 3 3 3 0 Filament-like plant protein, long coiled-coil FYVE PF01363.21 OAP59523.1 - 6.6 6.9 10.0 7.4 6.8 5.2 2.5 1 1 1 2 2 2 0 FYVE zinc finger ADIP PF11559.8 OAP59523.1 - 9.7 6.3 79.7 0.075 13.1 8.3 7.1 5 2 2 7 7 7 0 Afadin- and alpha -actinin-Binding Myb_DNA-bind_7 PF15963.5 OAP59524.1 - 2.1e-20 72.4 0.9 4.8e-20 71.2 0.1 2.1 2 0 0 2 2 2 1 Myb DNA-binding like UreF PF01730.16 OAP59525.1 - 3.8e-20 72.8 0.1 5.4e-20 72.3 0.1 1.2 1 0 0 1 1 1 1 UreF ABC1 PF03109.16 OAP59526.1 - 1.5e-32 112.2 0.0 2.7e-32 111.4 0.0 1.4 1 0 0 1 1 1 1 ABC1 family AMPK1_CBM PF16561.5 OAP59527.1 - 6.6e-30 103.2 0.1 1.2e-29 102.4 0.1 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase AMPKBI PF04739.15 OAP59527.1 - 9e-24 83.6 1.2 4.7e-23 81.2 1.2 2.3 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interaction domain RelB PF04221.12 OAP59527.1 - 0.08 12.9 0.0 0.23 11.5 0.0 1.7 1 0 0 1 1 1 0 RelB antitoxin CBM53 PF16760.5 OAP59527.1 - 0.097 13.3 0.1 0.26 11.9 0.1 1.7 1 0 0 1 1 1 0 Starch/carbohydrate-binding module (family 53) Peptidase_M22 PF00814.25 OAP59528.1 - 4.2e-85 285.7 0.0 4.9e-85 285.5 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.15 OAP59528.1 - 0.18 11.4 0.0 1.4 8.5 0.0 2.0 2 0 0 2 2 2 0 Carbamoyltransferase N-terminus SET PF00856.28 OAP59529.1 - 1.1e-18 68.1 0.0 2.2e-18 67.2 0.0 1.5 1 0 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.11 OAP59529.1 - 6.3e-09 36.6 0.1 1.3e-07 32.4 0.1 2.7 1 1 0 1 1 1 1 Rubisco LSMT substrate-binding EPL1 PF10513.9 OAP59530.1 - 1.3e-22 80.8 0.1 1.3e-22 80.8 0.1 2.4 2 1 0 2 2 2 1 Enhancer of polycomb-like EF-hand_1 PF00036.32 OAP59531.1 - 2.2e-26 89.4 15.9 5e-08 31.9 0.3 4.7 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.6 OAP59531.1 - 4.3e-23 81.5 13.2 2.1e-14 53.7 1.0 2.8 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 OAP59531.1 - 3.4e-19 67.0 10.7 0.00011 21.8 0.1 5.0 5 0 0 5 5 5 4 EF-hand domain EF-hand_5 PF13202.6 OAP59531.1 - 1.6e-17 62.1 13.2 1.8e-06 27.2 0.3 4.7 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.6 OAP59531.1 - 2.1e-10 40.3 14.5 0.00083 19.2 0.3 4.4 3 1 2 5 5 5 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 OAP59531.1 - 2.6e-06 27.7 0.1 0.011 16.1 0.0 2.4 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 OAP59531.1 - 6.1e-05 22.9 8.4 0.094 12.7 0.3 4.0 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 OAP59531.1 - 0.08 13.1 0.5 0.29 11.4 0.4 2.0 1 1 0 1 1 1 0 Dockerin type I domain Iso_dh PF00180.20 OAP59532.1 - 4.6e-103 345.0 0.0 5.9e-103 344.7 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase adh_short PF00106.25 OAP59534.1 - 1.3e-25 90.1 0.4 6e-19 68.3 0.2 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAP59534.1 - 5.5e-14 52.3 0.3 3.9e-12 46.2 0.1 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP59534.1 - 3.6e-07 30.3 0.1 5.1e-07 29.8 0.1 1.3 1 0 0 1 1 1 1 KR domain DUF3073 PF11273.8 OAP59534.1 - 0.12 13.1 0.0 0.23 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3073) MINDY_DUB PF04424.13 OAP59535.1 - 4.2e-21 75.1 0.0 7e-21 74.4 0.0 1.3 1 0 0 1 1 1 1 MINDY deubiquitinase Myb_DNA-binding PF00249.31 OAP59536.1 - 3.3e-09 36.8 0.0 1.8e-05 24.8 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OAP59536.1 - 0.0016 18.3 0.1 0.0016 18.3 0.1 2.6 2 0 0 2 2 2 1 Myb DNA-binding like Myb_DNA-bind_6 PF13921.6 OAP59536.1 - 0.0036 17.5 0.2 0.18 12.1 0.2 2.6 2 0 0 2 2 2 1 Myb-like DNA-binding domain DS PF01916.17 OAP59537.1 - 1.3e-128 428.3 0.0 1.5e-128 428.1 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase zf-C3HC4_3 PF13920.6 OAP59538.1 - 1.7e-10 40.6 15.2 2.8e-10 39.9 15.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) UCH PF00443.29 OAP59538.1 - 4.4e-07 29.7 0.0 6.8e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg PF12436.8 OAP59538.1 - 1.5e-05 24.4 0.0 0.037 13.3 0.0 2.3 2 0 0 2 2 2 2 ICP0-binding domain of Ubiquitin-specific protease 7 Prok-RING_4 PF14447.6 OAP59538.1 - 0.041 13.8 14.6 0.076 12.9 14.6 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 MORN PF02493.20 OAP59538.1 - 0.078 12.9 21.5 0.077 12.9 1.6 4.3 4 0 0 4 4 4 0 MORN repeat zf-RING_5 PF14634.6 OAP59538.1 - 0.75 9.8 16.0 1.5 8.9 16.0 1.5 1 0 0 1 1 1 0 zinc-RING finger domain Abhydrolase_6 PF12697.7 OAP59539.1 - 5.3e-19 69.7 0.0 6.1e-19 69.5 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 OAP59539.1 - 0.092 12.4 0.1 0.98 9.1 0.1 2.1 1 1 0 1 1 1 0 PGAP1-like protein adh_short PF00106.25 OAP59540.1 - 1.6e-19 70.1 0.0 6e-09 35.6 0.0 2.4 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAP59540.1 - 1.3e-13 51.1 0.0 5.6e-06 26.1 0.0 2.3 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase DUF1127 PF06568.11 OAP59540.1 - 0.14 11.9 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1127) MFS_1 PF07690.16 OAP59541.1 - 1.3e-35 122.9 33.3 3.4e-35 121.6 27.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Septin PF00735.18 OAP59542.1 - 1.2e-36 126.4 0.0 1.5e-12 47.4 0.0 3.1 3 0 0 3 3 3 3 Septin MMR_HSR1 PF01926.23 OAP59542.1 - 0.0024 17.9 0.0 0.0057 16.7 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase CDC45 PF02724.14 OAP59542.1 - 0.02 13.2 1.1 0.029 12.7 1.1 1.2 1 0 0 1 1 1 0 CDC45-like protein FtsK_SpoIIIE PF01580.18 OAP59542.1 - 0.031 13.7 0.0 0.05 13.0 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Ras PF00071.22 OAP59542.1 - 0.078 12.6 0.0 0.38 10.3 0.0 2.0 1 1 0 1 1 1 0 Ras family AAA_14 PF13173.6 OAP59542.1 - 0.12 12.4 0.0 0.3 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain DNA_pol_phi PF04931.13 OAP59542.1 - 3.8 5.5 9.5 5.4 5.0 9.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi XAP5 PF04921.14 OAP59542.1 - 4.3 7.1 6.4 0.47 10.2 2.1 1.5 2 0 0 2 2 2 0 XAP5, circadian clock regulator DOPA_dioxygen PF08883.11 OAP59544.1 - 9.8e-43 144.7 0.1 1.2e-42 144.4 0.1 1.1 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family ELP6 PF09807.9 OAP59545.1 - 2.3e-10 40.3 0.0 8.8e-07 28.6 0.0 2.2 2 0 0 2 2 2 2 Elongation complex protein 6 Glyco_hydro_16 PF00722.21 OAP59546.1 - 1.1e-37 129.2 0.5 3.1e-37 127.8 0.5 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 LysM PF01476.20 OAP59546.1 - 2.9e-16 59.2 0.8 1.4e-07 31.4 0.0 2.5 2 0 0 2 2 2 2 LysM domain Ribosomal_L37e PF01907.19 OAP59546.1 - 0.021 15.0 0.7 0.074 13.2 0.7 2.0 1 0 0 1 1 1 0 Ribosomal protein L37e NFACT-R_1 PF05670.13 OAP59548.1 - 2.9e-39 134.1 0.0 4.3e-39 133.5 0.0 1.3 1 0 0 1 1 1 1 NFACT protein RNA binding domain PVL_ORF50 PF07768.11 OAP59548.1 - 0.027 14.8 6.7 0.043 14.1 6.7 1.3 1 0 0 1 1 1 0 PVL ORF-50-like family Spem1 PF15670.5 OAP59548.1 - 0.23 11.0 4.3 0.31 10.6 4.3 1.1 1 0 0 1 1 1 0 Spermatid maturation protein 1 DUF1682 PF07946.14 OAP59548.1 - 1.4 8.0 11.5 2 7.5 11.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Thiolase_N PF00108.23 OAP59550.1 - 1.8e-20 73.4 0.3 8.5e-19 67.9 0.1 3.0 2 1 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 OAP59550.1 - 9.6e-13 47.9 0.3 3.1e-12 46.2 0.0 2.0 2 0 0 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III PF08545.10 OAP59550.1 - 1.1e-07 31.6 0.0 1e-05 25.3 0.1 2.6 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.26 OAP59550.1 - 4.1e-06 26.6 0.2 4.7e-05 23.1 0.2 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 OAP59550.1 - 0.018 15.0 0.2 0.25 11.4 0.0 2.6 2 0 0 2 2 2 0 Beta-ketoacyl synthase, C-terminal domain SmaI PF17411.2 OAP59550.1 - 0.14 11.3 0.0 0.25 10.5 0.0 1.3 1 0 0 1 1 1 0 Type II site-specific deoxyribonuclease Mito_carr PF00153.27 OAP59551.1 - 5.7e-42 141.6 6.5 1.3e-15 57.0 0.3 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF2620 PF10941.8 OAP59551.1 - 0.19 11.9 0.8 6.6 6.9 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function DUF2620 Oxidored_FMN PF00724.20 OAP59552.1 - 6.1e-38 131.0 0.0 8.1e-38 130.5 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF202 PF02656.15 OAP59553.1 - 6.5e-15 55.3 5.0 1e-14 54.7 1.9 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Nop14 PF04147.12 OAP59554.1 - 0.27 9.4 30.6 0.41 8.8 30.6 1.3 1 0 0 1 1 1 0 Nop14-like family PDEase_I PF00233.19 OAP59555.1 - 2e-66 224.1 0.0 3e-66 223.5 0.0 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase NPL4 PF05021.15 OAP59556.1 - 2.3e-135 450.9 0.0 2.8e-135 450.6 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.15 OAP59556.1 - 1.5e-71 239.2 0.4 2.3e-71 238.6 0.4 1.3 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.8 OAP59556.1 - 0.035 14.6 0.0 0.68 10.5 0.0 2.4 1 1 0 1 1 1 0 Nuclear pore localisation protein NPL4 DUF2417 PF10329.9 OAP59557.1 - 2e-81 272.9 1.5 2.7e-81 272.5 1.5 1.1 1 0 0 1 1 1 1 Region of unknown function (DUF2417) Spo7 PF03907.13 OAP59557.1 - 0.0024 17.4 1.4 0.0024 17.4 1.4 1.6 2 0 0 2 2 2 1 Spo7-like protein DUF2070 PF09843.9 OAP59557.1 - 0.19 10.0 12.4 0.26 9.5 12.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Trp_oprn_chp PF09534.10 OAP59557.1 - 0.9 9.3 8.2 0.67 9.7 5.6 1.9 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF4267 PF14087.6 OAP59557.1 - 5.1 7.2 6.7 1.7 8.7 2.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4267) Abhydrolase_6 PF12697.7 OAP59558.1 - 2.6e-23 83.8 0.0 4.5e-23 83.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAP59558.1 - 5.9e-12 45.8 0.0 9.6e-12 45.1 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAP59558.1 - 1.1e-07 31.4 0.0 1.9e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 OAP59558.1 - 0.024 14.3 0.0 0.038 13.7 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein DLH PF01738.18 OAP59558.1 - 0.024 14.2 0.0 2.3 7.7 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family LIDHydrolase PF10230.9 OAP59558.1 - 0.037 13.6 0.0 0.059 12.9 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Peptidase_S9 PF00326.21 OAP59558.1 - 0.056 12.9 0.0 5.3 6.4 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_5 PF12695.7 OAP59558.1 - 0.063 13.0 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family DEAD PF00270.29 OAP59559.1 - 5.3e-46 156.6 0.3 2.8e-45 154.2 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAP59559.1 - 8.8e-27 93.6 0.1 3.6e-25 88.5 0.1 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain MCPsignal PF00015.21 OAP59559.1 - 0.004 17.0 2.8 0.0091 15.8 2.8 1.6 1 0 0 1 1 1 1 Methyl-accepting chemotaxis protein (MCP) signalling domain AAA_22 PF13401.6 OAP59559.1 - 0.054 13.8 0.1 0.2 11.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain UTP25 PF06862.12 OAP59559.1 - 0.11 11.2 0.7 1.3 7.7 0.0 2.7 2 1 1 3 3 3 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 DHHW PF14286.6 OAP59559.1 - 0.65 9.3 4.9 7.1 5.8 0.0 2.7 2 0 0 2 2 2 0 DHHW protein Pribosyltran PF00156.27 OAP59560.1 - 5.1e-13 48.8 0.0 7e-13 48.4 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 OAP59560.1 - 0.058 12.8 0.0 0.078 12.4 0.0 1.1 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase AMP-binding PF00501.28 OAP59561.1 - 2.8e-64 217.3 0.8 1.6e-34 119.2 0.0 4.3 2 2 0 2 2 2 2 AMP-binding enzyme ADH_N PF08240.12 OAP59561.1 - 5.4e-29 100.3 0.9 1.4e-28 99.0 0.9 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAP59561.1 - 3.7e-15 56.1 0.0 1e-14 54.6 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DMAP_binding PF06464.11 OAP59561.1 - 4.2e-10 40.4 0.1 1.7e-09 38.4 0.1 2.1 2 0 0 2 2 2 1 DMAP1-binding Domain Glu_dehyd_C PF16912.5 OAP59561.1 - 3.2e-05 23.5 0.0 6.6e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 OAP59561.1 - 6.4e-05 22.4 0.0 0.00019 20.8 0.1 1.7 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.6 OAP59561.1 - 0.0022 19.1 0.0 0.0088 17.1 0.0 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ThrE PF06738.12 OAP59563.1 - 1.4e-56 191.6 16.4 3e-52 177.4 2.9 2.2 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 OAP59563.1 - 5.4e-13 49.2 25.6 6.8e-12 45.6 11.7 3.0 3 0 0 3 3 3 2 Threonine/Serine exporter, ThrE Abhydrolase_3 PF07859.13 OAP59564.1 - 1.4e-53 181.9 0.0 1.8e-53 181.6 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 OAP59564.1 - 4.2e-07 29.2 0.1 9.3e-07 28.1 0.1 1.5 1 1 0 1 1 1 1 Carboxylesterase family Say1_Mug180 PF10340.9 OAP59564.1 - 0.0019 17.1 0.0 0.004 16.1 0.0 1.5 1 1 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 OAP59564.1 - 0.0065 16.0 0.1 0.041 13.4 0.1 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 OAP59564.1 - 0.0097 15.5 0.0 0.042 13.4 0.0 1.8 2 0 0 2 2 2 1 Dienelactone hydrolase family Abhydro_lipase PF04083.16 OAP59564.1 - 0.013 15.1 0.0 0.025 14.2 0.0 1.4 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Hydrolase_4 PF12146.8 OAP59564.1 - 0.042 13.1 0.0 0.15 11.3 0.0 1.8 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OAP59564.1 - 0.051 14.2 0.3 0.092 13.3 0.3 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family AXE1 PF05448.12 OAP59564.1 - 0.083 11.5 0.0 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) CoA_transf_3 PF02515.17 OAP59565.1 - 5.4e-111 371.3 0.0 6.5e-111 371.0 0.0 1.1 1 0 0 1 1 1 1 CoA-transferase family III Ribonuc_L-PSP PF01042.21 OAP59566.1 - 2.5e-39 134.0 0.0 2.8e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP ADH_zinc_N PF00107.26 OAP59567.1 - 4.9e-28 97.7 0.2 9e-28 96.8 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAP59567.1 - 7.1e-12 46.5 0.0 1.2e-11 45.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAP59567.1 - 5.8e-06 26.2 0.0 3.8e-05 23.5 0.0 2.5 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 OAP59567.1 - 0.00048 19.5 0.6 0.00079 18.8 0.6 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HupF_HypC PF01455.18 OAP59567.1 - 0.0027 17.8 0.7 0.012 15.7 0.3 2.2 1 1 1 2 2 2 1 HupF/HypC family Ifi-6-16 PF06140.13 OAP59569.1 - 7.7e-08 32.1 31.7 7.7e-08 32.1 31.7 2.3 1 1 1 2 2 2 1 Interferon-induced 6-16 family F5_F8_type_C PF00754.25 OAP59570.1 - 0.00055 20.1 0.8 1.5 9.0 0.3 4.1 3 1 2 5 5 5 1 F5/8 type C domain BNR PF02012.20 OAP59570.1 - 0.0012 18.5 1.9 2.4 8.5 0.1 3.5 3 0 0 3 3 3 2 BNR/Asp-box repeat BNR_2 PF13088.6 OAP59570.1 - 0.072 12.4 0.1 0.83 8.9 0.0 2.1 1 1 0 2 2 2 0 BNR repeat-like domain NMO PF03060.15 OAP59571.1 - 1.2e-53 182.6 1.0 1.7e-53 182.2 1.0 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 OAP59571.1 - 5e-09 35.6 0.1 7.2e-06 25.2 0.0 2.8 2 1 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 OAP59571.1 - 0.0002 20.5 2.1 0.0002 20.5 2.1 1.7 2 0 0 2 2 2 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 OAP59571.1 - 0.0047 16.1 0.2 0.0081 15.3 0.2 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase DHO_dh PF01180.21 OAP59571.1 - 0.091 12.0 0.3 0.18 11.0 0.3 1.4 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase Radial_spoke_3 PF06098.11 OAP59571.1 - 0.18 11.0 0.0 0.28 10.4 0.0 1.2 1 0 0 1 1 1 0 Radial spoke protein 3 MFS_1 PF07690.16 OAP59572.1 - 5.2e-31 107.9 28.2 1e-30 106.9 28.2 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1180 PF06679.12 OAP59572.1 - 0.074 13.5 1.9 0.74 10.2 0.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1180) CoA_transf_3 PF02515.17 OAP59573.1 - 5.6e-48 163.9 0.3 1.5e-42 146.1 0.0 4.0 3 2 0 3 3 3 2 CoA-transferase family III Fungal_trans PF04082.18 OAP59574.1 - 3.5e-22 78.7 0.1 5.7e-22 78.0 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP59574.1 - 3.8e-09 36.5 8.4 6.3e-09 35.8 8.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short_C2 PF13561.6 OAP59575.1 - 1.3e-60 204.9 0.1 1.6e-60 204.6 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP59575.1 - 1.2e-48 165.2 0.2 1.5e-48 164.9 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAP59575.1 - 0.00022 21.2 0.3 0.0004 20.4 0.3 1.4 1 1 0 1 1 1 1 KR domain FMO-like PF00743.19 OAP59576.1 - 1.4e-14 53.5 1.7 4.8e-14 51.7 0.5 2.1 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OAP59576.1 - 5.2e-06 25.9 0.1 8.3e-05 22.0 0.0 2.6 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAP59576.1 - 5.4e-06 25.8 0.0 0.00014 21.1 0.0 2.5 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 OAP59576.1 - 0.0001 22.5 0.6 0.00027 21.1 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAP59576.1 - 0.00023 20.5 0.0 0.0078 15.5 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAP59576.1 - 0.064 13.2 0.0 4.4 7.3 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding adh_short PF00106.25 OAP59577.1 - 1.4e-38 132.4 0.0 2e-38 131.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP59577.1 - 6.2e-27 94.7 0.0 8.7e-27 94.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP59577.1 - 4.8e-06 26.6 0.1 2.6e-05 24.2 0.1 1.9 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 OAP59577.1 - 0.00056 19.4 0.0 0.018 14.5 0.0 2.1 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family Retrotrans_gag PF03732.17 OAP59577.1 - 0.0022 18.3 0.0 0.0043 17.3 0.0 1.4 1 0 0 1 1 1 1 Retrotransposon gag protein GDP_Man_Dehyd PF16363.5 OAP59577.1 - 0.0052 16.2 0.0 0.081 12.3 0.0 2.0 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 OAP59577.1 - 0.012 14.6 0.0 0.018 14.1 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family MFS_1 PF07690.16 OAP59578.1 - 1.1e-27 96.9 32.2 1.1e-27 96.9 32.2 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAP59578.1 - 0.0001 21.3 24.0 0.00019 20.5 24.0 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter Folate_carrier PF01770.18 OAP59578.1 - 0.0061 15.3 1.6 0.0061 15.3 1.6 1.8 2 0 0 2 2 2 1 Reduced folate carrier Lactamase_B PF00753.27 OAP59579.1 - 1.3e-08 35.1 1.6 3.9e-08 33.5 1.5 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OAP59579.1 - 0.0092 15.5 0.0 0.057 12.9 0.0 2.0 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Dabb PF07876.12 OAP59580.1 - 2.8e-12 47.1 0.0 3.1e-12 46.9 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain adh_short PF00106.25 OAP59581.1 - 3.9e-20 72.1 0.0 5.1e-20 71.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP59581.1 - 2.7e-19 69.6 0.0 3.7e-19 69.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP59581.1 - 6.1e-06 26.3 0.0 9.5e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OAP59581.1 - 0.011 14.8 0.1 0.016 14.4 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Rib_recp_KP_reg PF05104.12 OAP59582.1 - 2.3 9.2 9.4 20 6.2 9.4 2.4 1 1 0 1 1 1 0 Ribosome receptor lysine/proline rich region NmrA PF05368.13 OAP59583.1 - 1e-12 48.2 0.0 2e-12 47.2 0.0 1.4 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAP59583.1 - 6.3e-12 45.8 0.0 1.2e-11 44.9 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAP59583.1 - 1.5e-06 27.9 0.2 0.00041 19.9 0.1 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family KR PF08659.10 OAP59583.1 - 0.0016 18.4 0.0 0.0026 17.7 0.0 1.2 1 0 0 1 1 1 1 KR domain Semialdhyde_dh PF01118.24 OAP59583.1 - 0.0026 18.2 0.0 0.0043 17.5 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain PglD_N PF17836.1 OAP59583.1 - 0.036 14.7 0.1 0.072 13.7 0.1 1.5 1 0 0 1 1 1 0 PglD N-terminal domain DapB_N PF01113.20 OAP59583.1 - 0.058 13.5 0.0 0.13 12.3 0.0 1.6 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus RmlD_sub_bind PF04321.17 OAP59583.1 - 0.075 12.1 0.1 0.13 11.3 0.1 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain adh_short PF00106.25 OAP59584.1 - 3.3e-42 144.2 0.0 4.6e-42 143.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP59584.1 - 1.8e-28 99.7 0.0 2.3e-28 99.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP59584.1 - 1.4e-06 28.4 0.0 2.2e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 OAP59584.1 - 2.2e-05 24.0 0.0 2.8e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) F420_oxidored PF03807.17 OAP59584.1 - 0.041 14.5 0.0 0.1 13.2 0.0 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ADH_zinc_N PF00107.26 OAP59584.1 - 0.073 13.0 0.1 0.2 11.7 0.0 1.7 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Transp_cyt_pur PF02133.15 OAP59585.1 - 3e-82 276.7 44.7 4.6e-75 253.1 37.8 2.0 2 0 0 2 2 2 2 Permease for cytosine/purines, uracil, thiamine, allantoin Fic PF02661.18 OAP59586.1 - 0.059 14.3 0.6 45 5.0 0.2 3.8 3 1 0 3 3 3 0 Fic/DOC family PhyH PF05721.13 OAP59586.1 - 0.066 13.5 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 Phytanoyl-CoA dioxygenase (PhyH) Fungal_trans PF04082.18 OAP59587.1 - 2.1e-12 46.7 0.0 3.1e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sugar_tr PF00083.24 OAP59588.1 - 1.9e-66 224.8 30.9 1.7e-55 188.7 17.9 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 OAP59588.1 - 2.8e-27 95.6 26.9 4.5e-26 91.6 23.0 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_5 PF05631.14 OAP59588.1 - 0.0043 16.0 8.0 0.014 14.3 1.8 2.2 2 0 0 2 2 2 2 Sugar-tranasporters, 12 TM MFS_3 PF05977.13 OAP59588.1 - 0.083 11.3 2.6 1 7.7 0.1 2.2 2 0 0 2 2 2 0 Transmembrane secretion effector Sugar_tr PF00083.24 OAP59589.1 - 1.7e-78 264.5 19.0 1.9e-78 264.4 19.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP59589.1 - 2.6e-21 76.0 23.3 2.6e-21 76.0 23.3 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily zf-Mss51 PF13824.6 OAP59591.1 - 2.9e-29 100.9 5.4 6e-29 99.9 5.4 1.6 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.18 OAP59591.1 - 0.00036 20.6 0.3 0.00088 19.3 0.3 1.6 1 0 0 1 1 1 1 MYND finger DUF4902 PF16245.5 OAP59591.1 - 0.13 12.2 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4902) Laminin_G_3 PF13385.6 OAP59592.1 - 0.003 17.7 1.6 0.0069 16.5 1.6 1.7 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily NDUF_B8 PF05821.11 OAP59593.1 - 2.8e-10 40.3 0.1 3.9e-10 39.9 0.1 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) SNF2_N PF00176.23 OAP59594.1 - 8e-65 218.8 0.2 1.6e-64 217.9 0.2 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OAP59594.1 - 7.6e-20 71.3 0.9 1.8e-18 66.9 0.1 3.3 4 0 0 4 4 4 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAP59594.1 - 1.2e-10 41.7 0.1 1.1e-09 38.6 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HSA PF07529.13 OAP59594.1 - 4.5e-07 30.1 18.0 9.1e-07 29.1 15.7 2.8 2 0 0 2 2 2 1 HSA DEAD PF00270.29 OAP59594.1 - 9.7e-06 25.5 0.0 3.5e-05 23.6 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase DEAD_2 PF06733.15 OAP59594.1 - 0.058 13.0 0.4 0.22 11.1 0.0 2.2 2 0 0 2 2 2 0 DEAD_2 Sugar_tr PF00083.24 OAP59595.1 - 3.5e-90 303.0 17.6 4.5e-90 302.7 17.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP59595.1 - 1.3e-11 44.1 43.6 1e-06 27.9 14.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Gpr1_Fun34_YaaH PF01184.19 OAP59596.1 - 1.7e-34 119.2 16.0 2.1e-34 119.0 16.0 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family UL41A PF17591.2 OAP59596.1 - 6.2 7.0 8.5 13 5.9 2.5 3.0 1 1 1 3 3 3 0 Herpesvirus UL41A MARVEL PF01284.23 OAP59597.1 - 1.2e-08 35.1 6.7 4.4e-08 33.3 6.7 1.8 1 1 1 2 2 2 1 Membrane-associating domain APH PF01636.23 OAP59598.1 - 1.3e-05 25.2 0.0 7e-05 22.9 0.0 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family Ank_2 PF12796.7 OAP59600.1 - 2.7e-77 255.4 5.4 4.2e-11 43.3 0.0 9.2 5 3 3 8 8 8 8 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OAP59600.1 - 9e-59 194.8 22.0 2.2e-08 34.2 0.0 14.2 8 4 8 16 16 16 13 Ankyrin repeats (many copies) Ank_4 PF13637.6 OAP59600.1 - 2.3e-57 190.6 9.7 5.1e-06 26.9 0.0 12.9 8 4 5 13 13 13 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAP59600.1 - 5.2e-49 158.5 11.5 0.0017 18.7 0.0 18.1 19 0 0 19 19 19 12 Ankyrin repeat Ank PF00023.30 OAP59600.1 - 9.8e-43 142.8 23.7 3.2e-05 24.2 1.1 17.4 18 0 0 18 18 18 8 Ankyrin repeat HET PF06985.11 OAP59600.1 - 9.2e-24 84.5 0.0 2.7e-23 83.0 0.0 1.9 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SBP_bac_5 PF00496.22 OAP59600.1 - 0.039 12.9 0.1 0.072 12.0 0.1 1.3 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 5 Middle BRCA-2_helical PF09169.10 OAP59600.1 - 0.1 12.3 0.0 65 3.1 0.0 3.8 4 0 0 4 4 4 0 BRCA2, helical PRODH PF18327.1 OAP59600.1 - 1.2 9.4 5.0 13 6.1 0.0 4.3 4 0 0 4 4 4 0 Proline utilization A proline dehydrogenase N-terminal domain Peptidase_C97 PF05903.14 OAP59601.1 - 1.3e-05 25.1 0.1 2.5e-05 24.1 0.1 1.4 1 0 0 1 1 1 1 PPPDE putative peptidase domain DUF778 PF05608.12 OAP59601.1 - 0.0064 16.9 1.4 0.012 16.0 0.1 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF778) GrpE PF01025.19 OAP59601.1 - 0.013 15.2 1.0 0.036 13.7 0.0 1.9 2 0 0 2 2 2 0 GrpE DUF4105 PF13387.6 OAP59601.1 - 0.049 13.3 0.1 0.073 12.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4105) LRAT PF04970.13 OAP59601.1 - 0.051 13.9 1.6 0.22 11.8 0.4 2.4 2 1 1 3 3 3 0 Lecithin retinol acyltransferase DUF4796 PF16044.5 OAP59601.1 - 0.085 12.4 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4796) Presenilin PF01080.17 OAP59602.1 - 0.00014 20.8 5.4 0.00014 20.8 5.4 2.2 2 0 0 2 2 2 1 Presenilin Spt20 PF12090.8 OAP59602.1 - 0.0012 18.5 36.8 0.0012 18.5 36.8 2.9 3 0 0 3 3 3 1 Spt20 family TFIIA PF03153.13 OAP59602.1 - 0.0028 17.7 36.1 0.0028 17.7 36.1 2.4 2 1 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit Apt1 PF10351.9 OAP59602.1 - 1.6 7.5 16.7 0.0054 15.7 3.6 2.1 2 0 0 2 2 2 0 Golgi-body localisation protein domain NAD_binding_4 PF07993.12 OAP59604.1 - 3.5e-71 239.4 0.0 5.4e-71 238.8 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 OAP59604.1 - 9e-70 235.4 0.0 3e-69 233.7 0.0 1.8 2 0 0 2 2 2 1 AMP-binding enzyme Epimerase PF01370.21 OAP59604.1 - 1.6e-09 37.6 0.0 2.9e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Condensation PF00668.20 OAP59604.1 - 9.8e-09 34.4 0.0 9.9e-08 31.1 0.0 2.3 1 1 0 1 1 1 1 Condensation domain 3Beta_HSD PF01073.19 OAP59604.1 - 4.2e-08 32.5 0.0 1.3e-07 30.9 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding_C PF13193.6 OAP59604.1 - 1.1e-06 29.5 0.0 6.6e-06 27.0 0.0 2.4 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain PP-binding PF00550.25 OAP59604.1 - 6.6e-06 26.4 0.0 1.7e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site NAD_binding_10 PF13460.6 OAP59604.1 - 0.16 11.8 0.0 2.5 7.9 0.0 2.5 1 1 0 1 1 1 0 NAD(P)H-binding Pyr_redox_3 PF13738.6 OAP59605.1 - 4.4e-14 52.5 0.1 7.1e-12 45.2 0.1 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 OAP59605.1 - 1.8e-11 43.2 0.1 1.7e-09 36.7 0.1 2.8 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 OAP59605.1 - 5.6e-11 42.2 0.0 2.5e-07 30.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAP59605.1 - 1.9e-07 30.6 0.1 0.00026 20.3 0.0 2.6 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 OAP59605.1 - 5.6e-06 26.5 0.0 5.6e-06 26.5 0.0 2.1 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.20 OAP59605.1 - 2.9e-05 24.2 0.0 0.4 10.7 0.0 2.5 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 OAP59605.1 - 0.0025 17.1 0.0 0.15 11.3 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 OAP59605.1 - 0.0034 17.0 0.5 1.6 8.2 0.0 3.0 2 1 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OAP59605.1 - 0.11 11.6 0.0 0.19 10.7 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain ThiF PF00899.21 OAP59605.1 - 0.17 11.2 0.1 3.9 6.8 0.0 2.5 2 0 0 2 2 2 0 ThiF family adh_short PF00106.25 OAP59606.1 - 1.1e-37 129.3 0.0 1.7e-37 128.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP59606.1 - 1.2e-27 97.0 0.0 1.6e-27 96.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP59606.1 - 8.7e-05 22.5 0.0 0.0011 18.9 0.0 2.2 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 OAP59606.1 - 0.0037 16.8 0.0 0.0058 16.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 OAP59606.1 - 0.015 15.5 0.1 0.026 14.8 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 OAP59606.1 - 0.04 14.2 0.0 0.074 13.3 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain 3Beta_HSD PF01073.19 OAP59606.1 - 0.21 10.6 0.0 0.36 9.8 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Fungal_trans PF04082.18 OAP59607.1 - 6.7e-11 41.7 0.0 1.2e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP59607.1 - 2e-05 24.6 12.0 4.3e-05 23.5 12.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PhrC_PhrF PF11131.8 OAP59607.1 - 0.052 13.1 0.1 0.12 11.9 0.1 1.6 1 0 0 1 1 1 0 Rap-phr extracellular signalling adh_short PF00106.25 OAP59608.1 - 2.6e-34 118.4 0.0 3.6e-34 117.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP59608.1 - 1.9e-30 106.2 0.0 2.7e-30 105.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP59608.1 - 0.0031 17.5 0.1 0.049 13.6 0.1 2.1 1 1 0 1 1 1 1 KR domain Exotox-A_bind PF09101.10 OAP59608.1 - 0.048 13.0 0.0 0.072 12.4 0.0 1.2 1 0 0 1 1 1 0 Exotoxin A binding NUP214 PF16755.5 OAP59608.1 - 0.096 11.9 0.0 0.14 11.4 0.0 1.1 1 0 0 1 1 1 0 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 2-Hacid_dh_C PF02826.19 OAP59608.1 - 0.14 11.5 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 4HBT PF03061.22 OAP59609.1 - 8.7e-09 35.6 0.9 1.4e-08 34.9 0.9 1.4 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 OAP59609.1 - 5.9e-06 26.7 0.0 7.7e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Spt46 PF17734.1 OAP59610.1 - 3.2 7.5 5.6 3.2 7.5 5.6 1.1 1 0 0 1 1 1 0 Spermatogenesis-associated protein 46 ATP-synt_ab_Xtn PF16886.5 OAP59612.1 - 0.0082 16.0 0.1 0.024 14.5 0.1 1.7 2 0 0 2 2 2 1 ATPsynthase alpha/beta subunit N-term extension DUF726 PF05277.12 OAP59613.1 - 4.6e-123 410.5 2.1 4.6e-123 410.5 2.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF726) Phage_holin_3_6 PF07332.11 OAP59613.1 - 0.11 12.5 3.2 0.31 11.1 1.5 2.5 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Thioesterase PF00975.20 OAP59613.1 - 0.12 12.5 0.6 0.41 10.7 0.0 2.2 2 0 0 2 2 2 0 Thioesterase domain Bromo_TP PF07524.13 OAP59613.1 - 0.16 12.0 0.0 0.87 9.6 0.0 2.3 3 0 0 3 3 3 0 Bromodomain associated Pertussis_S1 PF02917.14 OAP59613.1 - 5.4 6.7 7.5 0.16 11.7 0.7 1.8 2 0 0 2 2 2 0 Pertussis toxin, subunit 1 Aha1_N PF09229.11 OAP59614.1 - 1e-40 139.1 0.2 2.2e-40 138.0 0.1 1.6 2 0 0 2 2 2 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 OAP59614.1 - 4.3e-19 69.0 0.8 7e-19 68.3 0.8 1.4 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein MRG PF05712.13 OAP59615.1 - 2e-41 141.5 0.0 5.8e-39 133.5 0.0 2.3 1 1 0 1 1 1 1 MRG Tudor-knot PF11717.8 OAP59615.1 - 5.3e-05 23.0 3.8 5.5e-05 23.0 0.6 2.4 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain Ribosomal_L9_C PF03948.14 OAP59615.1 - 0.1 13.1 0.1 1.5 9.3 0.0 2.4 2 0 0 2 2 2 0 Ribosomal protein L9, C-terminal domain Hid1 PF12722.7 OAP59615.1 - 7.1 4.6 5.8 11 4.0 5.8 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Cnl2_NKP2 PF09447.10 OAP59616.1 - 1.1e-20 73.6 0.3 1.9e-20 72.8 0.3 1.4 1 0 0 1 1 1 1 Cnl2/NKP2 family protein Bacillus_HBL PF05791.11 OAP59616.1 - 0.095 12.5 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) Utp14 PF04615.13 OAP59616.1 - 0.12 11.0 3.7 0.14 10.7 3.7 1.2 1 0 0 1 1 1 0 Utp14 protein FBPase PF00316.20 OAP59617.1 - 1.1e-69 233.7 0.0 1.5e-69 233.2 0.0 1.2 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Sugar_tr PF00083.24 OAP59618.1 - 5.6e-93 312.3 25.3 6.7e-93 312.0 25.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP59618.1 - 1.9e-19 69.8 61.2 3.1e-18 65.8 28.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2089 PF09862.9 OAP59619.1 - 0.5 10.4 1.6 17 5.5 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2089) 6PF2K PF01591.18 OAP59620.1 - 2.4e-74 249.4 0.6 3.8e-74 248.7 0.6 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 OAP59620.1 - 4.7e-40 137.4 0.0 8.9e-40 136.5 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) KTI12 PF08433.10 OAP59620.1 - 5.8e-06 26.0 0.0 1e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 OAP59620.1 - 0.00028 21.1 0.0 0.0046 17.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain Pterin_4a PF01329.19 OAP59620.1 - 0.26 11.5 0.1 0.26 11.5 0.1 2.2 3 0 0 3 3 3 0 Pterin 4 alpha carbinolamine dehydratase Aa_trans PF01490.18 OAP59621.1 - 1.9e-33 115.8 25.4 1.9e-33 115.8 25.4 1.4 2 0 0 2 2 2 1 Transmembrane amino acid transporter protein DUF2613 PF11021.8 OAP59621.1 - 0.012 15.7 2.1 0.078 13.1 0.6 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) Bap31 PF05529.12 OAP59621.1 - 1.3 8.8 5.0 0.6 10.0 1.9 2.1 2 0 0 2 2 2 0 Bap31/Bap29 transmembrane region GTA_holin_3TM PF11351.8 OAP59621.1 - 1.9 9.1 4.0 1.3 9.6 0.7 2.3 2 0 0 2 2 2 0 Holin of 3TMs, for gene-transfer release DUF5353 PF17304.2 OAP59622.1 - 9.7e-34 114.9 1.9 1.3e-33 114.6 1.9 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5353) Remorin_C PF03763.13 OAP59622.1 - 0.057 13.3 6.9 0.084 12.8 6.9 1.2 1 0 0 1 1 1 0 Remorin, C-terminal region Pex19 PF04614.12 OAP59622.1 - 0.071 12.9 4.5 0.093 12.5 4.5 1.1 1 0 0 1 1 1 0 Pex19 protein family DUF4337 PF14235.6 OAP59622.1 - 0.092 12.9 1.9 0.13 12.4 1.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Mit_KHE1 PF10173.9 OAP59622.1 - 0.22 11.6 0.5 0.28 11.2 0.5 1.1 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related ETRAMP PF09716.10 OAP59622.1 - 0.42 10.7 1.6 0.84 9.7 1.6 1.5 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) YtxH PF12732.7 OAP59622.1 - 1.3 9.6 6.7 3.3 8.3 6.7 1.8 1 0 0 1 1 1 0 YtxH-like protein DUF883 PF05957.13 OAP59622.1 - 5.5 7.7 6.7 0.6 10.8 0.5 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) V-SNARE_C PF12352.8 OAP59624.1 - 7.1e-14 51.8 0.1 3.6e-13 49.6 0.1 2.2 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 OAP59624.1 - 0.0018 18.2 0.1 0.0056 16.6 0.0 1.8 2 0 0 2 2 2 1 Sec20 Sigma70_r4 PF04545.16 OAP59624.1 - 0.035 13.6 0.1 0.08 12.5 0.1 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 DUF4047 PF13256.6 OAP59624.1 - 0.041 14.1 0.1 0.069 13.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) DHC_N1 PF08385.12 OAP59624.1 - 0.053 12.2 0.2 0.065 11.9 0.2 1.1 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 1 KxDL PF10241.9 OAP59624.1 - 0.068 13.5 5.8 0.11 12.7 2.9 2.5 2 1 1 3 3 3 0 Uncharacterized conserved protein HBM PF16591.5 OAP59624.1 - 0.076 12.4 5.2 0.1 12.0 3.8 1.8 1 1 1 2 2 2 0 Helical bimodular sensor domain TPR_MLP1_2 PF07926.12 OAP59624.1 - 0.21 11.7 9.0 0.49 10.5 7.9 2.2 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF4407 PF14362.6 OAP59624.1 - 8.4 5.6 10.2 32 3.7 10.2 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) FMO-like PF00743.19 OAP59625.1 - 5.1e-19 68.1 0.2 5.4e-18 64.7 0.2 2.0 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like GYF PF02213.16 OAP59625.1 - 4.7e-17 61.4 0.4 9.4e-17 60.4 0.4 1.5 1 0 0 1 1 1 1 GYF domain Pyr_redox_2 PF07992.14 OAP59625.1 - 4.4e-11 42.6 0.0 2.3e-08 33.6 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAP59625.1 - 7.1e-11 41.9 0.0 2.9e-10 39.9 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAP59625.1 - 3.6e-10 39.5 0.4 8.2e-08 31.8 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 OAP59625.1 - 9.7e-08 32.1 0.0 3e-07 30.6 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAP59625.1 - 6.9e-06 25.9 0.0 6.7e-05 22.6 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Shikimate_DH PF01488.20 OAP59625.1 - 0.0048 17.0 0.1 0.6 10.2 0.0 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.6 OAP59625.1 - 0.014 15.4 0.8 0.18 11.8 0.0 3.1 4 0 0 4 4 4 0 FAD-NAD(P)-binding Thi4 PF01946.17 OAP59625.1 - 0.02 14.1 0.1 0.035 13.3 0.1 1.3 1 0 0 1 1 1 0 Thi4 family DUF917 PF06032.12 OAP59626.1 - 1.2e-111 373.0 2.0 2.5e-111 371.9 2.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF917) Hydant_A_N PF05378.13 OAP59626.1 - 4.6e-31 107.9 0.0 1.1e-29 103.5 0.0 2.8 3 0 0 3 3 3 1 Hydantoinase/oxoprolinase N-terminal region Hydantoinase_A PF01968.18 OAP59626.1 - 5.9e-25 88.1 2.9 1.9e-20 73.3 0.1 3.4 2 1 0 2 2 2 2 Hydantoinase/oxoprolinase ROK PF00480.20 OAP59626.1 - 0.014 14.9 1.9 0.015 14.8 0.3 1.8 2 0 0 2 2 2 0 ROK family StbA PF06406.11 OAP59626.1 - 0.24 10.6 2.1 10 5.2 0.0 2.7 3 0 0 3 3 3 0 StbA protein BcrAD_BadFG PF01869.20 OAP59626.1 - 0.85 9.1 8.1 0.34 10.4 0.8 3.2 2 1 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family DIOX_N PF14226.6 OAP59627.1 - 1.1e-28 100.3 0.0 1.7e-28 99.7 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OAP59627.1 - 1.7e-17 63.7 0.0 2.8e-17 63.1 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Transp_cyt_pur PF02133.15 OAP59628.1 - 2.9e-90 303.2 36.3 2.9e-90 303.2 36.3 1.5 2 0 0 2 2 2 1 Permease for cytosine/purines, uracil, thiamine, allantoin Aldo_ket_red PF00248.21 OAP59629.1 - 1.8e-43 148.9 0.0 5.6e-42 143.9 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Fungal_trans PF04082.18 OAP59630.1 - 1.6e-23 83.1 0.3 2.5e-23 82.5 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF1989 PF09347.10 OAP59631.1 - 8.9e-52 175.1 0.1 1.5e-51 174.3 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) Polysacc_deac_1 PF01522.21 OAP59631.1 - 2.9e-16 59.5 0.0 5.5e-16 58.6 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 OAP59631.1 - 1.3e-06 28.2 0.1 2.1e-06 27.5 0.1 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) DUF2194 PF09960.9 OAP59631.1 - 0.11 10.8 0.0 0.16 10.3 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2194) CENP-F_leu_zip PF10473.9 OAP59632.1 - 0.0028 17.7 12.0 0.0028 17.7 12.0 6.3 1 1 2 5 5 5 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.6 OAP59632.1 - 0.0071 15.7 92.3 2.9 7.2 2.2 6.4 1 1 5 6 6 6 6 Growth-arrest specific micro-tubule binding DUF5486 PF17588.2 OAP59632.1 - 0.7 9.8 4.2 9.5 6.2 1.6 3.2 2 0 0 2 2 2 0 Family of unknown function (DUF5486) Sec20 PF03908.13 OAP59632.1 - 1.8 8.5 14.6 3.1 7.8 0.4 4.4 2 2 1 3 3 3 0 Sec20 TENA_THI-4 PF03070.16 OAP59633.1 - 0.038 13.8 0.0 9 6.0 0.0 2.2 2 0 0 2 2 2 0 TENA/THI-4/PQQC family HTH_19 PF12844.7 OAP59633.1 - 0.077 13.0 0.0 3.5 7.7 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain Hydrolase PF00702.26 OAP59633.1 - 0.1 12.8 0.0 0.21 11.8 0.0 1.7 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Isochorismatase PF00857.20 OAP59634.1 - 4.2e-32 111.7 0.0 1.2e-31 110.2 0.0 1.9 1 0 0 1 1 1 1 Isochorismatase family Zein-binding PF04576.15 OAP59634.1 - 0.38 11.1 1.1 5.3 7.4 0.3 2.3 2 0 0 2 2 2 0 Zein-binding TauD PF02668.16 OAP59639.1 - 7.8e-57 193.1 0.2 9.1e-57 192.9 0.2 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF1479 PF07350.12 OAP59639.1 - 0.018 13.8 0.1 0.036 12.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1479) TPR_11 PF13414.6 OAP59639.1 - 0.093 12.4 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 TPR repeat P16-Arc PF04699.14 OAP59640.1 - 1.2e-45 155.7 0.0 1.3e-45 155.5 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Dynactin_p62 PF05502.13 OAP59641.1 - 3.5e-172 573.5 0.2 4.6e-172 573.1 0.2 1.1 1 0 0 1 1 1 1 Dynactin p62 family Methyltransf_23 PF13489.6 OAP59642.1 - 1.9e-11 44.1 0.0 2.8e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAP59642.1 - 4.5e-10 40.0 0.0 9.9e-10 39.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAP59642.1 - 4.9e-07 30.4 0.0 2.4e-06 28.1 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAP59642.1 - 1.2e-05 26.0 0.0 2.3e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAP59642.1 - 0.00038 20.3 0.0 0.0014 18.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAP59642.1 - 0.064 12.6 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Ribosomal_S7e PF01251.18 OAP59643.1 - 3.8e-78 261.5 0.0 4.4e-78 261.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e ADH_zinc_N PF00107.26 OAP59644.1 - 6.9e-25 87.5 1.5 1.2e-24 86.7 1.5 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAP59644.1 - 5e-10 39.2 0.0 1.6e-09 37.6 0.0 1.9 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 OAP59644.1 - 2.1e-06 28.8 0.0 0.0013 19.8 0.0 2.6 1 1 0 2 2 2 2 Zinc-binding dehydrogenase TrkA_N PF02254.18 OAP59644.1 - 0.00023 21.4 0.0 0.00047 20.4 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain AlaDh_PNT_C PF01262.21 OAP59644.1 - 0.0036 16.6 0.4 0.0064 15.8 0.4 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain GST_N_3 PF13417.6 OAP59645.1 - 1.1e-09 38.5 0.0 2.9e-09 37.2 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OAP59645.1 - 6.4e-08 32.8 0.0 1.3e-07 31.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAP59645.1 - 2.7e-05 24.1 0.0 6.5e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OAP59645.1 - 4.1e-05 23.7 0.0 7.4e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OAP59645.1 - 0.0009 19.4 0.0 0.0039 17.4 0.0 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin2_C PF04399.13 OAP59645.1 - 0.018 14.8 0.0 0.031 14.1 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain GST_N PF02798.20 OAP59645.1 - 0.032 14.6 0.0 0.11 12.9 0.0 1.9 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_C_5 PF16865.5 OAP59645.1 - 0.083 13.5 0.1 0.17 12.5 0.1 1.6 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain COA2 PF17051.5 OAP59647.1 - 0.12 12.4 1.1 0.38 10.8 1.1 1.9 1 0 0 1 1 1 0 Cytochrome C oxidase assembly factor 2 zf-RING_2 PF13639.6 OAP59648.1 - 1.5e-12 47.7 5.1 2.3e-12 47.1 5.1 1.3 1 0 0 1 1 1 1 Ring finger domain PA PF02225.22 OAP59648.1 - 1.3e-09 37.9 0.0 3.9e-09 36.4 0.0 1.8 1 0 0 1 1 1 1 PA domain zf-RING_11 PF17123.5 OAP59648.1 - 6.9e-09 35.3 2.9 6.9e-09 35.3 2.9 1.8 2 0 0 2 2 2 1 RING-like zinc finger zf-rbx1 PF12678.7 OAP59648.1 - 1.7e-08 34.6 2.5 3.4e-08 33.7 2.5 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 OAP59648.1 - 3.8e-08 33.0 4.2 6.1e-08 32.4 4.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAP59648.1 - 5.4e-08 32.6 3.0 8.6e-08 31.9 3.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAP59648.1 - 1.3e-07 31.5 2.2 1.9e-07 30.9 2.2 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 OAP59648.1 - 1.1e-05 25.2 2.8 1.6e-05 24.7 2.8 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAP59648.1 - 5.4e-05 23.1 2.2 0.00043 20.2 2.8 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 OAP59648.1 - 0.0026 17.8 0.7 0.0051 16.8 0.7 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 OAP59648.1 - 0.0033 17.2 2.9 0.0056 16.5 2.9 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 OAP59648.1 - 0.052 13.7 2.5 0.14 12.4 2.5 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 OAP59648.1 - 0.13 12.5 2.3 0.35 11.1 2.3 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.6 OAP59648.1 - 0.18 11.6 2.9 0.33 10.8 2.9 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.5 OAP59648.1 - 0.22 11.2 2.9 0.4 10.4 2.9 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type PHD PF00628.29 OAP59648.1 - 0.53 10.2 3.0 0.96 9.4 3.0 1.5 1 0 0 1 1 1 0 PHD-finger RINGv PF12906.7 OAP59648.1 - 0.92 9.7 3.6 1.8 8.7 3.6 1.5 1 0 0 1 1 1 0 RING-variant domain zf-RING-like PF08746.11 OAP59648.1 - 1.4 9.3 3.0 2.5 8.5 3.0 1.4 1 0 0 1 1 1 0 RING-like domain MIP PF00230.20 OAP59649.1 - 6.9e-50 169.9 11.3 1e-49 169.3 11.3 1.1 1 0 0 1 1 1 1 Major intrinsic protein PRP21_like_P PF12230.8 OAP59650.1 - 3.3e-53 180.8 3.3 3.3e-53 180.8 3.3 2.2 2 1 0 2 2 2 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.20 OAP59650.1 - 2.9e-37 126.4 1.5 4.3e-20 71.4 0.0 2.3 2 0 0 2 2 2 2 Surp module zf_UBZ PF18439.1 OAP59650.1 - 0.0032 17.0 0.0 0.0086 15.7 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger PMT PF02366.18 OAP59651.1 - 2.6e-80 269.5 14.7 4.6e-80 268.7 14.7 1.4 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 OAP59651.1 - 1.3e-67 227.3 14.4 1.3e-67 227.3 14.4 2.4 2 0 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 OAP59651.1 - 6.2e-46 156.6 0.1 1e-45 155.8 0.1 1.3 1 0 0 1 1 1 1 MIR domain EB1 PF03271.17 OAP59652.1 - 9.7e-18 64.1 0.3 1.9e-17 63.2 0.3 1.5 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.31 OAP59652.1 - 3.2e-08 33.7 1.0 1.1e-07 32.0 0.3 1.9 2 0 0 2 2 2 1 Calponin homology (CH) domain Syja_N PF02383.18 OAP59652.1 - 0.066 12.5 0.0 0.066 12.5 0.0 1.1 1 0 0 1 1 1 0 SacI homology domain Whi5 PF08528.11 OAP59654.1 - 1.1e-09 37.6 0.9 2.2e-09 36.7 0.9 1.5 1 0 0 1 1 1 1 Whi5 like Lin-8 PF03353.15 OAP59654.1 - 2.2 7.8 7.8 0.16 11.5 0.3 2.2 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist Peptidase_C15 PF01470.17 OAP59657.1 - 8.4e-12 45.7 0.0 6.5e-09 36.2 0.0 2.9 2 1 0 2 2 2 2 Pyroglutamyl peptidase Mad3_BUB1_I PF08311.12 OAP59658.1 - 2e-42 144.1 0.0 3.2e-42 143.4 0.0 1.3 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Mad3_BUB1_II PF08171.11 OAP59658.1 - 1.1e-12 47.9 0.0 1.1e-11 44.7 0.0 2.4 2 0 0 2 2 2 1 Mad3/BUB1 homology region 2 Pkinase PF00069.25 OAP59658.1 - 3.8e-08 33.0 0.0 2.4e-07 30.4 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP59658.1 - 0.0076 15.6 0.0 0.035 13.4 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Mad3_BUB1_I_2 PF17014.5 OAP59658.1 - 0.11 12.6 0.0 0.36 10.9 0.0 1.8 2 0 0 2 2 2 0 Putative Mad3/BUB1 like region 1 protein Ribosomal_S4e PF00900.20 OAP59660.1 - 2.1e-37 126.9 0.5 5.3e-37 125.6 0.3 1.8 2 0 0 2 2 2 1 Ribosomal family S4e 40S_S4_C PF16121.5 OAP59660.1 - 4.7e-24 83.8 0.1 7.9e-24 83.0 0.1 1.4 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 OAP59660.1 - 6.3e-17 61.4 6.7 1.2e-16 60.6 6.7 1.5 1 0 0 1 1 1 1 RS4NT (NUC023) domain KOW PF00467.29 OAP59660.1 - 0.00015 21.5 2.9 0.00015 21.5 2.9 2.6 3 0 0 3 3 3 1 KOW motif S4 PF01479.25 OAP59660.1 - 0.02 14.6 0.0 0.041 13.6 0.0 1.6 1 0 0 1 1 1 0 S4 domain Semialdhyde_dhC PF02774.18 OAP59661.1 - 9e-36 123.7 0.0 1.2e-35 123.3 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 OAP59661.1 - 1.6e-28 99.6 0.0 5.1e-28 98.0 0.0 1.9 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DXP_reductoisom PF02670.16 OAP59661.1 - 0.028 15.1 0.0 0.074 13.8 0.0 1.7 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase YcaO_C PF18381.1 OAP59662.1 - 0.0052 16.7 0.0 0.0068 16.3 0.0 1.1 1 0 0 1 1 1 1 YcaO cyclodehydratase C-terminal domain p450 PF00067.22 OAP59663.1 - 1e-66 225.6 0.2 1.3e-66 225.2 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 Mannosyl_trans2 PF04188.13 OAP59664.1 - 1.4e-33 116.9 8.2 1.8e-33 116.5 8.2 1.1 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V) DUF4064 PF13273.6 OAP59664.1 - 1.6 9.0 8.7 0.08 13.2 1.5 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) p450 PF00067.22 OAP59665.1 - 1.9e-62 211.5 0.0 2.6e-62 211.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAA_hydrolase PF01557.18 OAP59666.1 - 1.2e-59 201.6 0.0 1.7e-59 201.1 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family EPTP PF03736.17 OAP59667.1 - 8.4e-49 163.3 8.2 5.4e-11 42.3 0.1 7.5 7 0 0 7 7 7 7 EPTP domain DUF5624 PF18538.1 OAP59667.1 - 5.6e-48 162.3 0.2 1.2e-47 161.2 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5624) Abhydrolase_6 PF12697.7 OAP59667.1 - 2.4e-16 61.0 0.2 1.9e-14 54.8 0.0 3.0 3 0 0 3 3 3 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAP59667.1 - 1.4e-14 54.4 0.0 3.5e-14 53.1 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Ndr PF03096.14 OAP59667.1 - 3.3e-05 22.7 0.0 5.5e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Ndr family Hydrolase_4 PF12146.8 OAP59667.1 - 0.00036 19.9 0.0 0.0014 18.0 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Lipocalin_3 PF12702.7 OAP59667.1 - 0.066 13.3 0.3 0.16 12.1 0.1 1.7 2 0 0 2 2 2 0 Lipocalin-like Velvet PF11754.8 OAP59669.1 - 2.2e-20 73.7 1.3 3.5e-15 56.6 0.1 3.3 2 2 1 3 3 3 2 Velvet factor GFA PF04828.14 OAP59670.1 - 2.2e-18 66.3 9.2 1.5e-10 41.2 0.1 3.7 3 1 0 3 3 3 2 Glutathione-dependent formaldehyde-activating enzyme Zn_ribbon_recom PF13408.6 OAP59670.1 - 0.058 13.9 9.4 0.44 11.1 0.1 3.6 3 0 0 3 3 3 0 Recombinase zinc beta ribbon domain DUF4567 PF15131.6 OAP59670.1 - 0.11 12.5 0.1 5.5 7.1 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4567) NOB1_Zn_bind PF08772.11 OAP59670.1 - 0.11 12.6 2.4 13 6.1 0.4 2.7 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like zf-NADH-PPase PF09297.11 OAP59670.1 - 3 7.6 17.2 1 9.1 0.2 3.6 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain Ribosomal_S27 PF01599.19 OAP59670.1 - 4.2 7.6 7.7 21 5.4 0.8 2.8 2 0 0 2 2 2 0 Ribosomal protein S27a Sugar_tr PF00083.24 OAP59671.1 - 4.3e-80 269.8 22.0 5e-80 269.6 22.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP59671.1 - 4e-29 101.6 49.9 7.8e-28 97.4 26.9 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily PhyH PF05721.13 OAP59672.1 - 0.00027 21.3 0.0 0.0027 18.0 0.0 2.0 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) FAD_binding_3 PF01494.19 OAP59673.1 - 2.5e-10 40.2 0.0 8.4e-10 38.4 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain DUF2407_C PF13373.6 OAP59674.1 - 3.2e-44 150.5 0.0 4.8e-44 149.9 0.0 1.3 1 0 0 1 1 1 1 DUF2407 C-terminal domain DUF2407 PF10302.9 OAP59674.1 - 6e-28 97.5 0.0 1.1e-27 96.5 0.0 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.23 OAP59674.1 - 0.0041 16.9 0.0 0.0069 16.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family V-SNARE PF05008.15 OAP59675.1 - 5.6e-22 77.9 3.6 5.6e-22 77.9 3.6 2.0 2 1 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 OAP59675.1 - 1.5e-18 66.8 5.4 1.5e-18 66.8 5.4 2.8 4 0 0 4 4 4 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 OAP59675.1 - 0.00023 21.0 2.3 0.00043 20.2 0.2 2.2 2 0 0 2 2 2 1 Sec20 DUF4407 PF14362.6 OAP59675.1 - 0.0073 15.7 5.1 0.0093 15.4 5.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) Fusion_gly PF00523.18 OAP59675.1 - 0.02 13.2 2.0 0.043 12.1 0.4 2.0 2 1 0 2 2 2 0 Fusion glycoprotein F0 DDE_Tnp_1 PF01609.21 OAP59675.1 - 0.023 14.4 0.4 0.029 14.0 0.4 1.3 1 0 0 1 1 1 0 Transposase DDE domain DUF1542 PF07564.11 OAP59675.1 - 0.023 14.8 0.4 0.056 13.6 0.4 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1542) SNARE PF05739.19 OAP59675.1 - 0.091 12.8 0.8 0.29 11.2 0.8 1.9 1 0 0 1 1 1 0 SNARE domain ARGLU PF15346.6 OAP59675.1 - 0.25 11.2 7.7 0.15 12.0 5.4 1.7 1 1 1 2 2 2 0 Arginine and glutamate-rich 1 Amino_oxidase PF01593.24 OAP59676.1 - 3.5e-16 59.5 0.0 1.5e-15 57.4 0.0 1.9 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OAP59676.1 - 1.7e-10 41.0 0.1 3.6e-10 39.9 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 OAP59676.1 - 5.8e-09 36.1 0.1 0.0017 18.4 0.0 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding DAO PF01266.24 OAP59676.1 - 1e-05 25.3 0.2 0.017 14.7 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Prenylcys_lyase PF07156.14 OAP59676.1 - 0.0076 15.4 0.0 0.019 14.1 0.0 1.6 1 1 0 1 1 1 1 Prenylcysteine lyase Pyr_redox_2 PF07992.14 OAP59676.1 - 0.015 14.6 0.1 1.5 8.0 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAP59676.1 - 0.1 11.8 0.1 0.58 9.4 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ATP_bind_3 PF01171.20 OAP59677.1 - 1.5e-19 70.4 0.0 2.4e-19 69.8 0.0 1.3 1 0 0 1 1 1 1 PP-loop family zn-ribbon_14 PF16503.5 OAP59677.1 - 1.2e-17 63.1 15.1 6.7e-17 60.7 4.8 4.0 4 0 0 4 4 4 2 Zinc-ribbon RecR PF02132.15 OAP59677.1 - 0.0022 17.5 0.8 0.0022 17.5 0.8 3.4 4 0 0 4 4 4 2 RecR protein tRNA_Me_trans PF03054.16 OAP59677.1 - 0.07 11.9 0.0 0.12 11.1 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase zf-UBR PF02207.20 OAP59677.1 - 1.5 9.0 6.2 3.4 7.9 0.6 2.6 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) zf-C4pol PF14260.6 OAP59677.1 - 1.6 9.3 6.7 12 6.4 1.1 3.0 2 0 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta AAA PF00004.29 OAP59678.1 - 1.9e-37 128.6 0.0 1e-36 126.3 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OAP59678.1 - 1.2e-09 37.8 0.0 3.2e-09 36.5 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 OAP59678.1 - 0.00041 20.8 0.7 0.024 15.0 0.0 3.2 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 OAP59678.1 - 0.00077 19.7 2.3 0.16 12.2 0.1 3.7 3 1 1 4 4 4 1 AAA domain AAA_33 PF13671.6 OAP59678.1 - 0.0016 18.6 0.0 0.0085 16.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 OAP59678.1 - 0.0034 17.1 0.0 0.0066 16.2 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 OAP59678.1 - 0.0085 16.2 0.0 0.025 14.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) ox_reductase_C PF08635.10 OAP59678.1 - 0.026 14.2 0.1 0.049 13.3 0.1 1.4 1 0 0 1 1 1 0 Putative oxidoreductase C terminal domain AAA_18 PF13238.6 OAP59678.1 - 0.04 14.5 0.1 0.23 12.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 OAP59678.1 - 0.043 13.7 0.0 0.082 12.8 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_14 PF13173.6 OAP59678.1 - 0.051 13.6 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 OAP59678.1 - 0.065 13.2 0.1 0.18 11.8 0.1 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 OAP59678.1 - 0.077 13.4 0.0 0.2 12.1 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.21 OAP59678.1 - 0.08 12.3 0.0 0.18 11.2 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 OAP59678.1 - 0.08 12.7 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.13 OAP59678.1 - 0.18 11.0 0.0 0.31 10.2 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_17 PF13207.6 OAP59678.1 - 2.7 8.4 4.8 0.76 10.2 0.1 2.6 4 0 0 4 4 4 0 AAA domain AAA_18 PF13238.6 OAP59679.1 - 0.0016 19.0 0.0 0.0048 17.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain PRK PF00485.18 OAP59679.1 - 0.0053 16.5 0.0 0.0081 15.9 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_16 PF13191.6 OAP59679.1 - 0.011 16.1 0.1 0.019 15.3 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain CTNNB1_binding PF08347.11 OAP59679.1 - 0.03 14.5 0.3 0.053 13.7 0.3 1.3 1 0 0 1 1 1 0 N-terminal CTNNB1 binding AAA_22 PF13401.6 OAP59679.1 - 0.032 14.5 0.0 0.065 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 OAP59679.1 - 0.049 13.9 0.1 0.13 12.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain CPT PF07931.12 OAP59679.1 - 0.1 12.5 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein LIM_bind PF01803.16 OAP59680.1 - 5.2e-53 180.0 0.0 5.2e-53 180.0 0.0 3.8 3 1 0 3 3 3 1 LIM-domain binding protein TIP49 PF06068.13 OAP59681.1 - 5.2e-165 548.8 0.0 6.3e-165 548.6 0.0 1.0 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 OAP59681.1 - 1.8e-24 85.6 0.0 8.2e-24 83.5 0.0 2.1 2 0 0 2 2 2 1 TIP49 AAA-lid domain AAA PF00004.29 OAP59681.1 - 1.3e-10 41.9 0.1 5.8e-07 30.0 0.1 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 OAP59681.1 - 6.3e-10 39.0 0.1 1.4e-06 28.2 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 OAP59681.1 - 2.4e-05 24.6 0.1 0.31 11.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 OAP59681.1 - 6e-05 23.5 0.1 0.00049 20.5 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 OAP59681.1 - 0.00019 21.8 0.6 0.06 13.7 0.2 2.3 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 OAP59681.1 - 0.0007 19.9 0.1 0.0028 17.9 0.1 1.9 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 OAP59681.1 - 0.0011 18.9 0.1 0.18 11.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 OAP59681.1 - 0.0013 18.5 0.1 0.82 9.3 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain Zeta_toxin PF06414.12 OAP59681.1 - 0.0056 16.0 0.2 0.013 14.8 0.2 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_25 PF13481.6 OAP59681.1 - 0.018 14.6 0.0 0.037 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 OAP59681.1 - 0.02 14.3 0.1 0.66 9.3 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ATPase PF06745.13 OAP59681.1 - 0.045 13.1 0.7 0.12 11.7 0.1 1.8 2 0 0 2 2 2 0 KaiC AAA_18 PF13238.6 OAP59681.1 - 0.046 14.3 0.0 0.13 12.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain DnaB_C PF03796.15 OAP59681.1 - 0.056 12.8 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_30 PF13604.6 OAP59681.1 - 0.057 13.1 0.2 0.75 9.5 0.1 2.3 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 OAP59681.1 - 0.057 13.1 0.1 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_14 PF13173.6 OAP59681.1 - 0.064 13.3 0.0 1.1 9.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 OAP59681.1 - 0.068 12.4 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 OAP59681.1 - 0.12 11.9 0.3 0.39 10.2 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region Ribosomal_L28 PF00830.19 OAP59682.1 - 6.8e-11 42.2 0.3 1.6e-10 41.0 0.3 1.6 1 0 0 1 1 1 1 Ribosomal L28 family DSBA PF01323.20 OAP59683.1 - 3e-27 95.7 0.0 3.7e-27 95.4 0.0 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain CAP_N PF01213.19 OAP59683.1 - 0.23 10.9 1.1 0.32 10.4 1.1 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal SNF2_N PF00176.23 OAP59684.1 - 4.6e-45 153.9 0.0 1.4e-40 139.1 0.0 2.2 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 OAP59684.1 - 1.7e-06 28.4 0.0 3.6e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAP59684.1 - 0.00033 20.7 0.0 0.26 11.3 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Ald_Xan_dh_C2 PF02738.18 OAP59685.1 - 2.2e-207 689.9 0.1 3.2e-207 689.4 0.1 1.2 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.21 OAP59685.1 - 1.7e-45 154.8 0.0 3.3e-45 153.9 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.17 OAP59685.1 - 1.7e-30 105.2 2.4 4.7e-30 103.8 0.0 3.1 5 0 0 5 5 5 1 CO dehydrogenase flavoprotein C-terminal domain Fer2_2 PF01799.20 OAP59685.1 - 1.7e-28 98.4 0.0 4e-28 97.3 0.0 1.7 1 0 0 1 1 1 1 [2Fe-2S] binding domain Ald_Xan_dh_C PF01315.22 OAP59685.1 - 2.5e-27 95.4 0.0 6.6e-27 94.1 0.0 1.8 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2 PF00111.27 OAP59685.1 - 2.2e-08 33.9 0.1 2.2e-08 33.9 0.1 2.0 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain SR-25 PF10500.9 OAP59686.1 - 1.5 8.4 28.0 0.023 14.3 11.2 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF4614 PF15391.6 OAP59686.1 - 4.2 7.3 23.3 5 7.1 5.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) KH_1 PF00013.29 OAP59687.1 - 3.9e-40 135.5 8.5 4.3e-15 55.3 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 OAP59687.1 - 1.6e-05 24.6 2.6 0.12 12.2 0.0 2.8 3 0 0 3 3 3 2 KH domain KH_4 PF13083.6 OAP59687.1 - 0.0013 18.6 5.2 0.071 13.0 0.1 3.1 3 0 0 3 3 3 2 KH domain Glyco_hydro_130 PF04041.13 OAP59689.1 - 1.1e-39 136.3 0.0 2.2e-39 135.3 0.0 1.4 1 1 0 1 1 1 1 beta-1,4-mannooligosaccharide phosphorylase Glyco_hydro_32N PF00251.20 OAP59689.1 - 2.1e-08 34.1 0.5 3.8e-05 23.4 0.0 3.0 3 0 0 3 3 3 2 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_43 PF04616.14 OAP59689.1 - 4.7e-08 32.7 0.7 0.00097 18.5 0.1 4.0 3 1 1 4 4 4 2 Glycosyl hydrolases family 43 DNA_pol_E_B PF04042.16 OAP59689.1 - 7.5e-05 22.2 0.4 0.00011 21.6 0.4 1.1 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Nup96 PF12110.8 OAP59690.1 - 8.1e-58 195.8 1.4 1.2e-57 195.3 1.4 1.2 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.14 OAP59690.1 - 3.9e-50 169.8 0.0 7.1e-50 169.0 0.0 1.4 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.6 OAP59690.1 - 3.4e-07 31.0 72.4 4.8e-06 27.3 35.1 9.8 3 2 5 8 8 8 3 Nucleoporin FG repeat region LisH_TPL PF17814.1 OAP59690.1 - 0.15 11.7 0.3 0.94 9.2 0.1 2.2 2 0 0 2 2 2 0 LisH-like dimerisation domain GET2 PF08690.10 OAP59691.1 - 6.4e-12 45.8 6.6 1.7e-11 44.3 2.6 2.6 1 1 0 2 2 2 1 GET complex subunit GET2 DUF919 PF06034.11 OAP59691.1 - 0.18 11.7 0.1 0.3 10.9 0.1 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF919) DUF3094 PF11293.8 OAP59691.1 - 0.2 11.4 1.5 0.54 10.0 0.1 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3094) AMP-binding PF00501.28 OAP59692.1 - 3.6e-86 289.4 0.1 4.9e-86 289.0 0.1 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAP59692.1 - 3e-27 95.4 0.2 7.7e-26 90.9 0.2 2.5 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 OAP59692.1 - 2.9e-20 71.9 1.2 6.8e-20 70.7 1.2 1.7 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus EF-hand_7 PF13499.6 OAP59693.1 - 1e-14 54.7 1.2 1.6e-08 34.9 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 OAP59693.1 - 2.4e-14 51.7 0.1 6.2e-06 25.4 0.0 3.5 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 OAP59693.1 - 1.1e-12 46.8 0.2 1.5e-05 24.5 0.1 3.5 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.6 OAP59693.1 - 1.8e-09 37.3 1.1 2.3e-06 27.4 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 OAP59693.1 - 0.0024 18.1 0.3 0.0052 17.1 0.0 1.7 2 0 0 2 2 2 1 EF-hand domain EF-hand_4 PF12763.7 OAP59693.1 - 0.005 16.8 0.0 0.019 14.9 0.0 1.8 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand IMS PF00817.20 OAP59694.1 - 1e-37 129.4 0.0 1.8e-37 128.6 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 OAP59694.1 - 8.8e-17 61.9 0.2 7.7e-16 58.9 0.2 2.2 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 OAP59694.1 - 4.8e-07 29.7 0.3 4.4e-05 23.6 0.0 3.2 3 0 0 3 3 3 1 IMS family HHH motif HHH_5 PF14520.6 OAP59694.1 - 0.0023 18.5 0.0 0.19 12.3 0.0 2.6 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH PF00633.23 OAP59694.1 - 0.027 14.3 0.0 0.13 12.2 0.1 2.1 2 0 0 2 2 2 0 Helix-hairpin-helix motif HHH_8 PF14716.6 OAP59694.1 - 0.048 14.0 0.1 0.17 12.3 0.0 1.9 2 0 0 2 2 2 0 Helix-hairpin-helix domain Amidohydro_1 PF01979.20 OAP59696.1 - 1.4e-12 47.6 0.0 1.9e-12 47.1 0.0 1.3 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 OAP59696.1 - 2.2e-11 43.9 1.0 3.2e-08 33.5 0.0 2.5 2 1 0 2 2 2 2 Amidohydrolase family Neocarzinostat PF00960.18 OAP59696.1 - 0.052 13.5 0.6 0.096 12.7 0.6 1.4 1 0 0 1 1 1 0 Neocarzinostatin family C2 PF00168.30 OAP59697.1 - 3.6e-27 94.7 0.1 1.1e-16 60.9 0.0 2.8 3 0 0 3 3 3 2 C2 domain Reprolysin_5 PF13688.6 OAP59698.1 - 4.5e-59 199.9 11.6 4.5e-59 199.9 11.6 2.5 2 1 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 OAP59698.1 - 3.2e-52 177.3 4.6 6.8e-52 176.2 4.6 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 OAP59698.1 - 8.1e-51 172.6 6.3 1.6e-50 171.6 6.3 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.23 OAP59698.1 - 4.6e-17 62.6 32.3 4.6e-17 62.6 32.3 4.3 3 2 0 3 3 3 1 Disintegrin Reprolysin_3 PF13582.6 OAP59698.1 - 7.6e-14 52.3 0.1 2.2e-13 50.8 0.1 1.9 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like ADAM_CR_2 PF17771.1 OAP59698.1 - 6.7e-05 23.3 8.4 6.7e-05 23.3 8.4 5.3 1 1 2 3 3 3 1 ADAM cysteine-rich domain Pep_M12B_propep PF01562.19 OAP59698.1 - 0.0007 19.8 0.1 0.0021 18.3 0.1 1.8 1 0 0 1 1 1 1 Reprolysin family propeptide Peptidase_M66 PF10462.9 OAP59698.1 - 0.081 11.9 0.1 0.14 11.1 0.1 1.3 1 0 0 1 1 1 0 Peptidase M66 Reprolysin PF01421.19 OAP59698.1 - 0.09 12.7 17.9 0.023 14.6 10.1 3.4 1 1 1 2 2 2 0 Reprolysin (M12B) family zinc metalloprotease Aminotran_1_2 PF00155.21 OAP59699.1 - 3.4e-54 184.4 0.0 4.2e-54 184.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 OAP59699.1 - 0.0031 16.1 0.0 0.0048 15.5 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 OAP59699.1 - 0.12 11.6 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase Aminotran_5 PF00266.19 OAP59699.1 - 0.18 10.8 0.0 0.28 10.1 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V MgsA_C PF12002.8 OAP59700.1 - 1.9e-61 206.9 1.2 3.5e-61 206.0 0.1 2.0 3 0 0 3 3 2 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 OAP59700.1 - 8.4e-24 83.7 0.3 1.9e-23 82.6 0.3 1.6 1 0 0 1 1 1 1 AAA C-terminal domain AAA PF00004.29 OAP59700.1 - 1.4e-13 51.5 0.1 3.7e-13 50.1 0.1 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 OAP59700.1 - 2.1e-09 37.4 0.0 4.8e-09 36.2 0.0 1.5 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 OAP59700.1 - 4e-05 23.1 0.2 0.15 11.4 0.0 2.3 1 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 OAP59700.1 - 5.1e-05 23.3 0.0 0.00065 19.7 0.0 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OAP59700.1 - 9.5e-05 22.8 0.7 0.057 13.8 0.1 3.1 2 1 1 3 3 3 1 AAA ATPase domain Sigma54_activat PF00158.26 OAP59700.1 - 0.00023 20.9 0.1 0.013 15.2 0.1 2.3 1 1 0 1 1 1 1 Sigma-54 interaction domain ResIII PF04851.15 OAP59700.1 - 0.00061 19.8 0.3 0.43 10.6 0.0 2.3 1 1 1 2 2 2 2 Type III restriction enzyme, res subunit AAA_3 PF07726.11 OAP59700.1 - 0.0023 17.8 0.0 0.0057 16.5 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OAP59700.1 - 0.0033 17.7 0.3 0.014 15.7 0.2 2.2 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 OAP59700.1 - 0.0034 16.6 0.0 0.0059 15.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.6 OAP59700.1 - 0.0054 16.8 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain zf-C2HC_2 PF13913.6 OAP59700.1 - 0.039 13.9 0.0 0.24 11.4 0.0 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type AAA_30 PF13604.6 OAP59700.1 - 0.043 13.5 0.7 0.12 12.1 0.7 1.7 1 1 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.6 OAP59700.1 - 0.049 13.7 0.0 0.094 12.8 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain zf_C2H2_13 PF18508.1 OAP59700.1 - 0.057 13.0 0.3 0.26 10.9 0.7 1.9 2 0 0 2 2 2 0 Zinc finger domain AAA_18 PF13238.6 OAP59700.1 - 0.13 12.8 0.1 0.35 11.4 0.0 1.8 2 0 0 2 2 1 0 AAA domain TIP49 PF06068.13 OAP59700.1 - 0.14 11.4 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain TsaE PF02367.17 OAP59700.1 - 0.15 12.1 0.0 0.33 10.9 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SKI PF01202.22 OAP59700.1 - 0.17 12.0 0.1 0.37 10.9 0.1 1.6 1 0 0 1 1 1 0 Shikimate kinase AAA_24 PF13479.6 OAP59700.1 - 0.19 11.4 0.0 0.32 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 OAP59700.1 - 0.2 10.8 0.0 0.36 10.0 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Pro_dh PF01619.18 OAP59702.1 - 3.4e-61 207.4 0.1 4.6e-61 206.9 0.1 1.2 1 0 0 1 1 1 1 Proline dehydrogenase DAO PF01266.24 OAP59702.1 - 1.5e-22 80.7 0.0 2.6e-22 79.9 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAP59702.1 - 0.037 14.3 0.0 0.21 11.9 0.0 2.2 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Mito_carr PF00153.27 OAP59703.1 - 4.6e-48 161.1 7.8 2e-18 66.1 0.2 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.19 OAP59703.1 - 0.0013 19.0 4.8 0.0015 18.8 0.3 2.9 2 1 1 3 3 3 1 Tim17/Tim22/Tim23/Pmp24 family Cupin_2 PF07883.11 OAP59704.1 - 5.8e-08 32.3 0.2 1.6e-06 27.7 0.2 2.3 1 1 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 OAP59704.1 - 1.5e-06 27.8 0.0 2.4e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Cupin P5CR_dimer PF14748.6 OAP59706.1 - 3.7e-19 68.9 2.9 5.6e-19 68.3 1.0 2.2 3 0 0 3 3 3 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 OAP59706.1 - 4e-15 56.2 0.0 1e-14 54.9 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent DHDPS PF00701.22 OAP59707.1 - 2.1e-10 39.8 0.2 4.8e-08 32.1 0.0 2.0 1 1 1 2 2 2 2 Dihydrodipicolinate synthetase family Fungal_trans PF04082.18 OAP59708.1 - 2.2e-18 66.2 0.3 8.9e-18 64.3 0.3 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Aldedh PF00171.22 OAP59709.1 - 1.3e-96 324.0 0.0 1.6e-96 323.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Aldedh PF00171.22 OAP59710.1 - 5.3e-138 460.4 0.1 6.1e-138 460.2 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 OAP59710.1 - 0.012 14.7 0.0 0.018 14.1 0.0 1.3 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) PGM_PMM_II PF02879.16 OAP59710.1 - 0.056 14.1 0.0 0.29 11.8 0.0 2.1 2 0 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PagP PF07017.11 OAP59710.1 - 0.38 10.2 1.1 1.9 7.9 0.1 2.4 2 1 1 3 3 3 0 Antimicrobial peptide resistance and lipid A acylation protein PagP Calreticulin PF00262.18 OAP59711.1 - 3.1e-171 569.2 17.3 4.1e-171 568.8 17.3 1.2 1 0 0 1 1 1 1 Calreticulin family Aldolase_II PF00596.21 OAP59712.1 - 4.1e-44 150.7 0.0 4.8e-44 150.5 0.0 1.0 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain GCN5L1 PF06320.13 OAP59713.1 - 3.2e-14 53.1 3.5 4.1e-14 52.7 3.5 1.1 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) Tektin PF03148.14 OAP59713.1 - 0.00049 19.0 1.1 0.00064 18.6 1.1 1.2 1 0 0 1 1 1 1 Tektin family DUF2884 PF11101.8 OAP59713.1 - 0.0047 16.5 0.8 0.0047 16.5 0.8 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF2884) DUF2205 PF10224.9 OAP59713.1 - 0.0087 16.0 1.7 0.017 15.1 1.7 1.6 1 1 0 1 1 1 1 Short coiled-coil protein DUF2968 PF11180.8 OAP59713.1 - 0.0089 15.7 2.6 0.013 15.1 2.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2968) DUF4515 PF14988.6 OAP59713.1 - 0.018 14.9 2.7 0.025 14.4 2.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4515) OmpH PF03938.14 OAP59713.1 - 0.025 14.9 3.9 0.032 14.6 3.9 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) EzrA PF06160.12 OAP59713.1 - 0.054 11.7 3.9 0.064 11.4 3.9 1.0 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Mt_ATP-synt_B PF05405.14 OAP59713.1 - 0.06 13.0 0.8 0.1 12.2 0.7 1.4 1 1 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Sec34 PF04136.15 OAP59713.1 - 0.068 13.1 2.1 0.098 12.5 1.7 1.5 1 1 0 1 1 1 0 Sec34-like family DUF4349 PF14257.6 OAP59713.1 - 0.069 12.6 8.3 0.17 11.3 8.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4349) CHASE3 PF05227.13 OAP59713.1 - 0.078 12.9 2.8 0.098 12.6 1.4 1.7 1 1 1 2 2 2 0 CHASE3 domain DUF3450 PF11932.8 OAP59713.1 - 0.08 12.2 7.3 0.11 11.8 7.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) TMPIT PF07851.13 OAP59713.1 - 0.082 12.1 1.1 0.099 11.9 1.1 1.1 1 0 0 1 1 1 0 TMPIT-like protein NYD-SP28_assoc PF14775.6 OAP59713.1 - 0.15 12.2 1.8 0.43 10.7 1.1 2.0 1 1 1 2 2 2 0 Sperm tail C-terminal domain YabA PF06156.13 OAP59713.1 - 0.24 12.1 4.3 0.46 11.2 4.3 1.5 1 1 0 1 1 1 0 Initiation control protein YabA APG6_N PF17675.1 OAP59713.1 - 0.3 11.6 10.5 0.95 10.0 10.5 1.8 1 1 0 1 1 1 0 Apg6 coiled-coil region TBCC_N PF16752.5 OAP59713.1 - 0.31 11.5 6.5 6.9 7.1 5.7 2.3 1 1 1 2 2 2 0 Tubulin-specific chaperone C N-terminal domain UPF0242 PF06785.11 OAP59713.1 - 0.34 11.0 5.3 0.43 10.7 5.3 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Prefoldin_2 PF01920.20 OAP59713.1 - 0.35 10.9 6.4 0.19 11.7 2.3 2.2 1 1 1 2 2 2 0 Prefoldin subunit bZIP_1 PF00170.21 OAP59713.1 - 0.42 10.7 5.8 1.4 9.1 4.7 2.3 1 1 1 2 2 2 0 bZIP transcription factor DUF4407 PF14362.6 OAP59713.1 - 0.5 9.7 4.5 0.63 9.4 4.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Vps39_1 PF10366.9 OAP59714.1 - 1.4e-31 109.0 0.0 3.9e-30 104.3 0.0 2.9 3 1 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.9 OAP59714.1 - 6.4e-28 97.4 0.0 2.8e-27 95.3 0.0 2.2 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.22 OAP59714.1 - 2.1e-13 50.5 0.0 4.8e-13 49.3 0.0 1.5 1 1 0 1 1 1 1 CNH domain Clathrin PF00637.20 OAP59714.1 - 1e-07 31.9 4.1 5.6e-07 29.5 0.5 3.1 3 0 0 3 3 3 1 Region in Clathrin and VPS TPR_1 PF00515.28 OAP59714.1 - 0.052 13.4 0.3 5.3 7.0 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Gon7 PF08738.10 OAP59715.1 - 7.4e-12 45.3 6.8 5.9e-11 42.4 4.5 2.0 1 1 1 2 2 2 2 Gon7 family PdaC PF13739.6 OAP59715.1 - 0.18 12.8 3.9 0.26 12.3 3.9 1.3 1 0 0 1 1 1 0 Deacetylase PdaC HbrB PF08539.11 OAP59716.1 - 6.1e-51 172.8 0.0 1.7e-50 171.3 0.0 1.8 1 0 0 1 1 1 1 HbrB-like PMC2NT PF08066.12 OAP59716.1 - 0.027 15.1 1.0 0.11 13.2 0.1 2.3 2 0 0 2 2 2 0 PMC2NT (NUC016) domain Hydrolase_4 PF12146.8 OAP59717.1 - 3e-12 46.3 0.0 1.1e-06 28.1 0.0 2.0 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OAP59717.1 - 1.5e-09 37.8 0.0 9.8e-09 35.2 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAP59717.1 - 5.3e-08 33.7 0.0 6.8e-08 33.4 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family PLDc_2 PF13091.6 OAP59717.1 - 0.0002 21.3 0.1 0.00033 20.6 0.1 1.3 1 0 0 1 1 1 1 PLD-like domain Peptidase_S9 PF00326.21 OAP59717.1 - 0.00022 20.8 0.0 0.00031 20.3 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 OAP59717.1 - 0.0067 16.0 0.1 0.0091 15.6 0.1 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_4 PF08386.10 OAP59717.1 - 0.025 14.7 0.0 0.04 14.0 0.0 1.3 1 0 0 1 1 1 0 TAP-like protein HisG_C PF08029.11 OAP59717.1 - 0.045 13.9 0.1 0.077 13.2 0.1 1.4 1 0 0 1 1 1 0 HisG, C-terminal domain DUF3425 PF11905.8 OAP59718.1 - 5.8e-14 52.1 3.8 5.1e-13 49.1 3.8 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 OAP59718.1 - 0.00043 20.3 4.5 0.0007 19.6 4.5 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 OAP59718.1 - 0.0077 16.3 6.7 0.014 15.4 6.7 1.3 1 0 0 1 1 1 1 Basic region leucine zipper DUF2275 PF10039.9 OAP59719.1 - 1.5 8.9 8.1 3.4 7.7 8.1 1.7 1 1 0 1 1 1 0 Predicted integral membrane protein (DUF2275) Plasmodium_Vir PF05795.11 OAP59719.1 - 1.8 7.9 2.7 1.8 7.9 0.0 1.9 2 0 0 2 2 2 0 Plasmodium vivax Vir protein VSP PF03302.13 OAP59719.1 - 6.2 5.6 8.3 0.092 11.6 1.1 1.5 2 0 0 2 2 2 0 Giardia variant-specific surface protein Abhydrolase_3 PF07859.13 OAP59720.1 - 1.5e-35 123.0 0.0 1e-25 90.9 0.0 2.6 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 OAP59720.1 - 0.075 11.9 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Steryl acetyl hydrolase Fis1_TPR_C PF14853.6 OAP59721.1 - 1.2e-25 89.3 1.7 1.8e-25 88.7 1.7 1.3 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 OAP59721.1 - 6.7e-18 64.1 0.1 1.1e-17 63.3 0.1 1.4 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.17 OAP59721.1 - 0.0016 18.4 3.1 0.0016 18.4 3.1 1.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 OAP59721.1 - 0.021 15.4 0.4 0.056 14.1 0.4 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF2957 PF11170.8 OAP59721.1 - 0.059 12.2 0.0 0.084 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2957) Spc24 PF08286.11 OAP59722.1 - 2.3e-36 124.2 5.1 3.9e-35 120.3 0.6 2.2 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 CLZ PF16526.5 OAP59722.1 - 0.031 14.6 9.0 0.09 13.1 2.3 2.4 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels APG6_N PF17675.1 OAP59722.1 - 0.058 13.9 11.8 0.1 13.1 11.8 1.4 1 1 0 1 1 1 0 Apg6 coiled-coil region Laminin_II PF06009.12 OAP59722.1 - 0.065 13.2 7.6 0.88 9.6 1.3 2.2 1 1 1 2 2 2 0 Laminin Domain II FlaC_arch PF05377.11 OAP59722.1 - 0.073 13.5 4.2 4.9 7.6 0.7 3.0 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Streptin-Immun PF11083.8 OAP59722.1 - 0.092 13.2 0.4 0.59 10.6 0.0 2.1 2 0 0 2 2 2 0 Lantibiotic streptin immunity protein WDCP PF15390.6 OAP59722.1 - 0.1 10.9 2.1 0.12 10.7 2.1 1.0 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family SHE3 PF17078.5 OAP59722.1 - 0.14 11.8 9.1 0.12 12.0 1.3 2.1 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 Exonuc_VII_L PF02601.15 OAP59722.1 - 0.23 11.0 4.5 0.29 10.7 4.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Atg14 PF10186.9 OAP59722.1 - 0.26 10.3 4.9 0.33 10.0 4.9 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 V_ATPase_I PF01496.19 OAP59722.1 - 0.29 9.0 1.7 0.31 8.9 1.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family THOC7 PF05615.13 OAP59722.1 - 0.31 11.3 8.3 0.45 10.8 8.3 1.3 1 0 0 1 1 1 0 Tho complex subunit 7 SlyX PF04102.12 OAP59722.1 - 0.35 11.5 8.3 0.86 10.3 1.5 2.5 2 1 0 2 2 2 0 SlyX Prefoldin_2 PF01920.20 OAP59722.1 - 0.41 10.6 8.5 1.4 8.9 2.3 2.2 2 0 0 2 2 2 0 Prefoldin subunit DUF4337 PF14235.6 OAP59722.1 - 0.44 10.7 2.7 0.68 10.0 2.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Nsp1_C PF05064.13 OAP59722.1 - 0.5 10.2 5.4 3.1 7.6 1.3 2.2 2 0 0 2 2 2 0 Nsp1-like C-terminal region Uso1_p115_C PF04871.13 OAP59722.1 - 0.54 10.6 11.0 2.2 8.7 11.0 1.8 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Csm1_N PF18504.1 OAP59722.1 - 0.69 10.3 8.1 1.4 9.3 2.3 2.5 2 1 0 2 2 2 0 Csm1 N-terminal domain GAS PF13851.6 OAP59722.1 - 1.1 8.6 10.8 0.61 9.4 3.6 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding PEP-utilisers_N PF05524.13 OAP59722.1 - 1.4 9.1 7.8 1.9 8.7 2.1 2.3 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal YabA PF06156.13 OAP59722.1 - 1.6 9.4 5.4 2.7 8.7 1.9 2.2 1 1 1 2 2 2 0 Initiation control protein YabA DUF4164 PF13747.6 OAP59722.1 - 1.9 8.8 12.6 1.7 8.9 9.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) Sec2p PF06428.11 OAP59722.1 - 2.6 8.1 10.1 9.9 6.2 0.9 2.3 1 1 0 2 2 2 0 GDP/GTP exchange factor Sec2p Phage_GPO PF05929.11 OAP59722.1 - 2.7 7.5 7.1 14 5.2 7.1 1.9 1 1 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Nup54 PF13874.6 OAP59722.1 - 3.5 7.7 11.0 10 6.2 10.1 2.1 2 1 0 2 2 2 0 Nucleoporin complex subunit 54 Spc7 PF08317.11 OAP59722.1 - 4.1 6.2 11.2 7 5.4 11.2 1.3 1 1 0 1 1 1 0 Spc7 kinetochore protein ADIP PF11559.8 OAP59722.1 - 7.1 6.7 12.7 1.9 8.6 2.7 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding HR1 PF02185.16 OAP59722.1 - 7.9 6.7 13.1 12 6.1 1.8 2.5 2 1 0 2 2 2 0 Hr1 repeat DUF4140 PF13600.6 OAP59722.1 - 7.9 7.0 10.4 9.4 6.8 2.7 2.5 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) XhlA PF10779.9 OAP59722.1 - 9.4 6.5 6.3 7.3 6.9 1.2 2.3 2 0 0 2 2 2 0 Haemolysin XhlA S4 PF01479.25 OAP59723.1 - 5.4e-15 54.8 0.0 9e-15 54.1 0.0 1.4 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.6 OAP59723.1 - 0.057 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 S4 domain Pyr_redox_2 PF07992.14 OAP59724.1 - 7.2e-51 173.2 0.3 8.6e-51 172.9 0.3 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAP59724.1 - 5.5e-19 68.5 0.1 1.3e-17 64.1 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAP59724.1 - 6.5e-17 61.9 0.9 6.4e-15 55.5 0.1 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 OAP59724.1 - 9.7e-05 22.8 0.2 0.0053 17.2 0.1 2.7 2 1 0 2 2 2 1 Putative NAD(P)-binding NAD_binding_8 PF13450.6 OAP59724.1 - 0.00019 21.6 0.9 0.18 12.1 0.2 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 OAP59724.1 - 0.00029 20.1 0.0 0.0057 15.8 0.0 2.8 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 OAP59724.1 - 0.00037 19.8 0.3 0.0025 17.1 0.0 2.2 2 1 0 2 2 2 1 Thi4 family DAO PF01266.24 OAP59724.1 - 0.0061 16.2 3.2 2.8 7.4 0.0 3.4 2 2 1 3 3 3 2 FAD dependent oxidoreductase FAD_oxidored PF12831.7 OAP59724.1 - 0.0065 15.9 0.8 0.29 10.4 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 OAP59724.1 - 0.0077 15.5 0.0 1.8 7.8 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain Shikimate_DH PF01488.20 OAP59724.1 - 0.041 13.9 0.1 16 5.5 0.1 3.0 2 1 1 3 3 3 0 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.24 OAP59724.1 - 0.047 12.8 5.2 2.8 6.9 0.2 3.6 2 2 1 4 4 4 0 FAD binding domain GIDA PF01134.22 OAP59724.1 - 0.4 9.7 10.2 3.5 6.6 0.2 4.3 2 2 3 5 5 5 0 Glucose inhibited division protein A Malic_M PF03949.15 OAP59726.1 - 1.1e-90 303.4 0.2 1.5e-90 303.0 0.2 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 OAP59726.1 - 1.9e-63 213.6 0.0 2.9e-63 213.0 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Phage_int_SAM_5 PF13102.6 OAP59726.1 - 0.067 13.5 0.0 0.14 12.5 0.0 1.5 1 0 0 1 1 1 0 Phage integrase SAM-like domain Ldh_2 PF02615.14 OAP59727.1 - 2.2e-88 296.6 0.0 2.5e-88 296.5 0.0 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase adh_short PF00106.25 OAP59729.1 - 0.00097 18.6 0.0 0.0013 18.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP59729.1 - 0.0012 18.5 0.0 0.0012 18.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Glyoxalase PF00903.25 OAP59730.1 - 3.6e-05 24.0 0.1 0.00037 20.7 0.1 2.0 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily adh_short_C2 PF13561.6 OAP59731.1 - 8.8e-42 143.3 0.0 1.2e-40 139.5 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP59731.1 - 1.2e-38 132.5 0.0 2.3e-37 128.3 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAP59731.1 - 7e-07 29.3 0.0 1e-06 28.8 0.0 1.2 1 0 0 1 1 1 1 KR domain YAcAr PF10686.9 OAP59731.1 - 0.24 11.4 0.5 5.7 7.0 0.1 2.3 1 1 1 2 2 2 0 YspA, cpYpsA-related SLOG family GDP_Man_Dehyd PF16363.5 OAP59731.1 - 0.26 10.7 0.0 0.51 9.7 0.0 1.5 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase p450 PF00067.22 OAP59732.1 - 4.6e-42 144.3 0.0 5.8e-42 144.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Xan_ur_permease PF00860.20 OAP59733.1 - 8.4e-24 84.0 37.0 4.3e-23 81.6 33.2 3.0 2 1 0 2 2 2 1 Permease family Nucleos_tra2_N PF01773.20 OAP59733.1 - 6.8 7.4 11.3 0.36 11.5 0.8 3.7 4 0 0 4 4 4 0 Na+ dependent nucleoside transporter N-terminus ADH_N PF08240.12 OAP59734.1 - 5.4e-17 61.7 0.2 1.1e-16 60.6 0.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAP59734.1 - 9.9e-09 35.3 0.0 1.7e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_25 PF13649.6 OAP59734.1 - 0.0015 19.2 0.3 0.01 16.5 0.2 2.2 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAP59734.1 - 0.0033 17.2 0.1 0.0053 16.6 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAP59734.1 - 0.0071 17.0 0.0 0.022 15.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Sugar_tr PF00083.24 OAP59735.1 - 3.3e-94 316.3 20.0 7.5e-94 315.1 20.0 1.5 1 1 1 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP59735.1 - 2.2e-13 49.9 41.5 3e-12 46.1 28.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PspA_IM30 PF04012.12 OAP59736.1 - 0.064 12.8 1.4 0.079 12.5 0.0 1.7 2 0 0 2 2 2 0 PspA/IM30 family adh_short PF00106.25 OAP59737.1 - 3.9e-32 111.3 0.1 6.9e-24 84.4 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAP59737.1 - 8e-16 58.3 0.0 7.1e-11 42.1 0.0 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP59737.1 - 1.9e-09 37.7 0.0 2.9e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OAP59737.1 - 0.037 13.1 0.1 0.063 12.4 0.1 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Epimerase PF01370.21 OAP59737.1 - 0.098 12.1 0.2 0.26 10.7 0.1 1.7 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAP59737.1 - 0.11 11.9 0.1 0.19 11.1 0.1 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Rad51 PF08423.11 OAP59738.1 - 4.1e-08 32.8 0.0 1.8e-07 30.7 0.0 1.9 1 1 0 1 1 1 1 Rad51 AAA_25 PF13481.6 OAP59738.1 - 3.4e-06 26.8 0.0 9e-06 25.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain ATPase PF06745.13 OAP59738.1 - 2.6e-05 23.7 0.0 0.0001 21.7 0.0 1.9 2 0 0 2 2 2 1 KaiC RecA PF00154.21 OAP59738.1 - 0.001 18.6 0.0 0.002 17.6 0.0 1.4 1 0 0 1 1 1 1 recA bacterial DNA recombination protein DnaB_C PF03796.15 OAP59738.1 - 0.0019 17.6 0.1 0.0049 16.2 0.0 1.7 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain AAA PF00004.29 OAP59738.1 - 0.012 16.0 0.0 0.092 13.2 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 OAP59738.1 - 0.079 12.7 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 OAP59738.1 - 0.081 12.6 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 OAP59738.1 - 0.085 12.8 0.0 0.19 11.6 0.0 1.6 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea ATP_bind_1 PF03029.17 OAP59738.1 - 0.099 12.4 0.1 0.55 10.0 0.0 1.9 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_19 PF13245.6 OAP59738.1 - 0.11 12.9 0.0 6.4 7.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 OAP59738.1 - 0.11 12.7 0.2 2.9 8.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 OAP59738.1 - 0.13 12.5 0.0 0.35 11.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.22 OAP59738.1 - 0.14 11.3 0.0 0.36 10.0 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain Pkinase PF00069.25 OAP59739.1 - 1.1e-73 247.9 0.0 1.4e-73 247.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP59739.1 - 5.4e-29 101.3 0.0 8e-29 100.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAP59739.1 - 9.8e-08 31.6 0.0 1.4e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OAP59739.1 - 0.00015 20.7 0.0 0.00025 20.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OAP59739.1 - 0.00056 19.9 0.1 0.00084 19.3 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 OAP59739.1 - 0.00062 19.2 0.0 0.0012 18.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Cpn60_TCP1 PF00118.24 OAP59740.1 - 5.8e-159 529.8 0.4 6.5e-159 529.7 0.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Herpes_UL6 PF01763.16 OAP59740.1 - 0.035 12.6 0.0 0.053 12.0 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL6 like Nop PF01798.18 OAP59741.1 - 1.1e-87 293.4 0.2 2e-87 292.5 0.2 1.5 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 OAP59741.1 - 1.4e-18 67.0 0.2 5.4e-18 65.1 0.0 2.2 2 0 0 2 2 2 1 NOP5NT (NUC127) domain DMT_YdcZ PF04657.13 OAP59741.1 - 0.046 14.0 0.1 0.077 13.3 0.1 1.2 1 0 0 1 1 1 0 Putative inner membrane exporter, YdcZ HHH_2 PF12826.7 OAP59741.1 - 0.16 12.1 0.3 14 5.9 0.1 3.4 3 0 0 3 3 3 0 Helix-hairpin-helix motif DUF3767 PF12597.8 OAP59743.1 - 7.3e-12 45.0 0.7 3.1e-06 26.9 0.3 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF3767) DUF1744 PF08490.12 OAP59744.1 - 6.3e-145 482.7 0.1 9.1e-145 482.2 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 OAP59744.1 - 1.4e-82 277.5 0.3 2.2e-82 276.9 0.3 1.3 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 OAP59744.1 - 1.3e-15 57.1 0.0 2.3e-12 46.4 0.0 3.7 3 1 0 3 3 3 2 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 OAP59744.1 - 3e-07 30.3 0.1 1e-06 28.6 0.1 1.9 1 1 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 OAP59744.1 - 7.5e-05 22.8 0.0 0.00031 20.8 0.0 2.1 1 0 0 1 1 1 1 RNase_H superfamily ADK_lid PF05191.14 OAP59744.1 - 0.051 13.6 0.2 0.21 11.6 0.0 2.2 2 0 0 2 2 2 0 Adenylate kinase, active site lid UPF1_Zn_bind PF09416.10 OAP59744.1 - 0.09 12.7 0.1 0.58 10.1 0.0 2.5 2 0 0 2 2 2 0 RNA helicase (UPF2 interacting domain) TFIID_20kDa PF03847.13 OAP59745.1 - 5.6e-23 81.2 0.0 8.9e-23 80.6 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Adaptin_binding PF10199.9 OAP59745.1 - 0.0032 18.1 1.5 0.0032 18.1 1.5 2.1 2 1 0 2 2 2 1 Alpha and gamma adaptin binding protein p34 ERp29 PF07749.12 OAP59745.1 - 0.0051 17.7 0.0 0.0051 17.7 0.0 3.2 3 1 0 3 3 3 1 Endoplasmic reticulum protein ERp29, C-terminal domain ATG19_autophagy PF12744.7 OAP59745.1 - 0.2 10.8 2.2 0.38 9.9 2.2 1.4 1 0 0 1 1 1 0 Autophagy protein Atg19, Atg8-binding BAR_2 PF10455.9 OAP59747.1 - 2.2e-57 194.4 5.1 3.6e-57 193.7 5.1 1.3 1 1 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 OAP59747.1 - 7.2e-22 78.2 6.4 1.8e-15 57.2 1.2 2.1 2 0 0 2 2 2 2 BAR domain Arfaptin PF06456.13 OAP59747.1 - 0.05 13.2 1.5 0.13 11.9 0.1 2.2 2 0 0 2 2 2 0 Arfaptin-like domain BAR_3 PF16746.5 OAP59747.1 - 0.067 12.9 3.9 0.18 11.5 0.4 2.3 2 1 0 2 2 2 0 BAR domain of APPL family Mob1_phocein PF03637.17 OAP59748.1 - 1.9e-22 80.1 0.5 1.9e-22 80.1 0.5 1.6 2 0 0 2 2 2 1 Mob1/phocein family CxC6 PF18721.1 OAP59748.1 - 0.036 14.3 3.9 0.074 13.3 3.9 1.4 1 0 0 1 1 1 0 CxC6 like cysteine cluster associated with KDZ transposases cobW PF02492.19 OAP59749.1 - 3.9e-12 46.1 0.3 4.7e-12 45.9 0.3 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.6 OAP59749.1 - 0.00043 20.9 0.0 0.00049 20.7 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OAP59749.1 - 0.00072 20.0 0.0 0.00085 19.7 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain TsaE PF02367.17 OAP59749.1 - 0.0044 17.0 0.0 0.0045 17.0 0.0 1.1 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 OAP59749.1 - 0.0067 16.9 0.2 0.0077 16.8 0.2 1.1 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 OAP59749.1 - 0.011 15.5 0.1 0.012 15.4 0.1 1.2 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.6 OAP59749.1 - 0.011 15.5 0.1 0.011 15.4 0.1 1.1 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 OAP59749.1 - 0.013 14.8 0.0 0.015 14.6 0.0 1.1 1 0 0 1 1 1 0 Zeta toxin AAA_22 PF13401.6 OAP59749.1 - 0.015 15.6 0.0 0.019 15.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 OAP59749.1 - 0.015 15.8 0.2 0.019 15.5 0.2 1.2 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 OAP59749.1 - 0.016 15.1 0.0 0.016 15.1 0.0 1.1 1 0 0 1 1 1 0 RsgA GTPase MMR_HSR1 PF01926.23 OAP59749.1 - 0.017 15.2 0.1 0.023 14.8 0.1 1.2 1 0 0 1 1 1 0 50S ribosome-binding GTPase T2SSE PF00437.20 OAP59749.1 - 0.019 14.0 0.1 0.019 14.0 0.1 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein ATPase_2 PF01637.18 OAP59749.1 - 0.025 14.5 0.0 0.029 14.3 0.0 1.1 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea NTPase_1 PF03266.15 OAP59749.1 - 0.04 13.8 0.2 0.048 13.6 0.2 1.1 1 0 0 1 1 1 0 NTPase AAA_14 PF13173.6 OAP59749.1 - 0.046 13.8 0.1 0.057 13.5 0.1 1.2 1 0 0 1 1 1 0 AAA domain MobB PF03205.14 OAP59749.1 - 0.12 12.3 0.2 0.16 11.9 0.2 1.2 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Rad17 PF03215.15 OAP59749.1 - 0.12 12.3 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 Rad17 P-loop domain TrwB_AAD_bind PF10412.9 OAP59749.1 - 0.19 10.6 0.0 0.22 10.4 0.0 1.1 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Viral_helicase1 PF01443.18 OAP59749.1 - 0.19 11.4 0.1 0.22 11.2 0.1 1.1 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase dNK PF01712.19 OAP59749.1 - 0.2 11.5 0.1 0.24 11.2 0.1 1.1 1 0 0 1 1 1 0 Deoxynucleoside kinase cobW PF02492.19 OAP59750.1 - 7.8e-31 107.0 0.0 1.1e-30 106.6 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 OAP59750.1 - 6.8e-06 25.9 0.0 1.3e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain Pkinase PF00069.25 OAP59751.1 - 1.4e-11 44.3 0.0 1.9e-10 40.6 0.0 2.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP59751.1 - 3.1e-11 43.1 0.0 3.9e-10 39.5 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase DUF2661 PF10860.8 OAP59751.1 - 0.21 11.7 0.0 0.51 10.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2661) SAP30_Sin3_bdg PF13867.6 OAP59752.1 - 7.2e-08 32.6 0.0 3.8e-07 30.3 0.0 2.1 2 0 0 2 2 2 1 Sin3 binding region of histone deacetylase complex subunit SAP30 NUDE_C PF04880.13 OAP59752.1 - 0.13 12.7 5.5 0.3 11.6 5.5 1.5 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region zf-H2C2_2 PF13465.6 OAP59753.1 - 5.8e-06 26.5 10.2 2.2e-05 24.6 3.0 4.2 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2 PF00096.26 OAP59753.1 - 1.2e-05 25.5 24.5 0.00069 19.9 4.5 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 OAP59753.1 - 0.01 15.8 1.0 6.3 6.9 0.0 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OAP59753.1 - 0.02 15.2 1.4 0.11 12.8 0.2 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 OAP59753.1 - 0.029 15.2 20.4 0.048 14.5 3.0 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger FOXP-CC PF16159.5 OAP59753.1 - 0.045 14.4 2.4 0.1 13.2 0.3 2.5 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-H2C2_5 PF13909.6 OAP59753.1 - 5.9 6.7 14.2 3 7.7 0.2 3.6 3 0 0 3 3 3 0 C2H2-type zinc-finger domain BRO1 PF03097.18 OAP59754.1 - 2.7e-131 438.0 3.4 2.7e-131 438.0 3.4 2.4 3 0 0 3 3 3 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 OAP59754.1 - 1.9e-72 244.0 18.0 1.9e-72 244.0 18.0 1.8 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV DUF2383 PF09537.10 OAP59754.1 - 0.15 12.4 7.2 1.4 9.3 0.5 4.1 5 0 0 5 5 5 0 Domain of unknown function (DUF2383) GlutR_dimer PF00745.20 OAP59754.1 - 0.2 12.1 0.1 0.2 12.1 0.1 2.9 3 0 0 3 3 3 0 Glutamyl-tRNAGlu reductase, dimerisation domain DUF4226 PF10774.9 OAP59754.1 - 0.94 9.8 6.3 0.23 11.8 0.9 2.8 2 2 0 2 2 2 0 Domain of unknown function (DUF4226) DnaJ_C PF01556.18 OAP59755.1 - 1.8e-36 125.4 0.0 2.4e-36 125.0 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 OAP59755.1 - 2.7e-22 78.7 2.3 5.3e-22 77.7 2.3 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 OAP59755.1 - 3e-11 43.5 17.8 5.4e-11 42.7 17.8 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 OAP59755.1 - 0.74 9.8 17.0 0.14 12.2 3.1 3.4 1 1 2 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein Lon_C PF05362.13 OAP59756.1 - 1.5e-63 214.0 0.0 3.3e-63 213.0 0.0 1.6 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 OAP59756.1 - 8e-35 120.6 0.0 2.1e-34 119.2 0.0 1.8 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 OAP59756.1 - 8.5e-22 78.0 0.0 2.1e-21 76.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 OAP59756.1 - 1.2e-06 28.6 0.0 2.7e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 OAP59756.1 - 3.2e-06 27.4 0.0 9.3e-06 25.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) ChlI PF13541.6 OAP59756.1 - 6e-06 26.1 0.0 1.7e-05 24.7 0.0 1.8 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_22 PF13401.6 OAP59756.1 - 3.2e-05 24.2 0.0 0.00049 20.4 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_PrkA PF08298.11 OAP59756.1 - 4.1e-05 22.7 0.0 8.1e-05 21.7 0.0 1.4 1 0 0 1 1 1 1 PrkA AAA domain RuvB_N PF05496.12 OAP59756.1 - 5.9e-05 22.9 0.0 0.00068 19.4 0.0 2.7 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 OAP59756.1 - 0.00025 21.5 1.0 0.0022 18.4 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA_18 PF13238.6 OAP59756.1 - 0.0037 17.8 1.3 0.078 13.5 0.0 3.1 3 0 0 3 3 3 1 AAA domain SKI PF01202.22 OAP59756.1 - 0.0058 16.8 0.1 0.51 10.5 0.0 2.7 2 0 0 2 2 2 1 Shikimate kinase IstB_IS21 PF01695.17 OAP59756.1 - 0.01 15.6 0.0 0.067 12.9 0.0 2.1 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_14 PF13173.6 OAP59756.1 - 0.021 14.8 0.0 0.055 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 OAP59756.1 - 0.048 13.6 0.0 0.15 12.0 0.0 1.8 1 0 0 1 1 1 0 RsgA GTPase AAA_30 PF13604.6 OAP59756.1 - 0.054 13.2 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 OAP59756.1 - 0.067 13.1 0.2 1.5 8.7 0.0 2.9 2 1 1 3 3 3 0 NTPase RNA_helicase PF00910.22 OAP59756.1 - 0.07 13.5 0.0 0.21 12.0 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_7 PF12775.7 OAP59756.1 - 0.13 11.8 0.7 0.25 10.8 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region DNTTIP1_dimer PF18192.1 OAP59756.1 - 0.2 12.1 2.1 3.7 8.0 0.3 3.0 2 1 0 2 2 2 0 DNTTIP1 dimerisation domain ABC_tran PF00005.27 OAP59756.1 - 0.75 10.3 4.1 0.85 10.1 0.0 2.9 3 0 0 3 3 3 0 ABC transporter DUF445 PF04286.12 OAP59756.1 - 1.9 8.2 8.3 0.74 9.6 2.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF445) KH_8 PF17903.1 OAP59758.1 - 1.4e-28 98.8 0.0 2.9e-28 97.8 0.0 1.6 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 OAP59758.1 - 0.043 13.7 0.0 0.1 12.4 0.0 1.7 1 0 0 1 1 1 0 KH domain DUF5414 PF17435.2 OAP59758.1 - 0.12 12.0 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5414) MFS_1 PF07690.16 OAP59759.1 - 8.1e-14 51.3 43.5 5.9e-13 48.5 43.5 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAP59759.1 - 3.2e-05 23.0 9.8 3.2e-05 23.0 9.8 2.8 2 1 0 2 2 2 1 Sugar (and other) transporter Sugar_tr PF00083.24 OAP59761.1 - 2.1e-102 343.3 31.1 2.4e-102 343.1 31.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP59761.1 - 6.7e-33 114.1 32.1 6.7e-33 114.1 32.1 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily p450 PF00067.22 OAP59762.1 - 1.5e-62 211.9 0.0 2e-62 211.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.20 OAP59763.1 - 8.5e-51 172.6 0.0 1.3e-50 172.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 OAP59763.1 - 3.8e-27 95.2 0.0 8.2e-27 94.2 0.0 1.6 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.21 OAP59763.1 - 4.7e-18 65.8 0.1 1.3e-17 64.4 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain baeRF_family10 PF18854.1 OAP59763.1 - 0.14 12.4 0.0 11 6.3 0.0 2.6 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 10 Fungal_trans_2 PF11951.8 OAP59764.1 - 3.7e-10 39.2 2.1 9.2e-10 37.9 2.1 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Rer1 PF03248.13 OAP59766.1 - 2.2e-79 265.1 4.9 2.6e-79 264.9 4.9 1.0 1 0 0 1 1 1 1 Rer1 family ECH_1 PF00378.20 OAP59767.1 - 2.2e-75 253.2 0.2 2.8e-75 252.9 0.2 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAP59767.1 - 7.2e-35 121.1 0.6 1.2e-34 120.3 0.6 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Aldedh PF00171.22 OAP59768.1 - 6.7e-158 526.0 0.1 7.6e-158 525.8 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 OAP59768.1 - 0.00019 21.0 0.0 0.43 10.0 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) LuxC PF05893.14 OAP59768.1 - 0.0012 17.9 0.1 0.0019 17.3 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF5133 PF17196.4 OAP59768.1 - 2.6 8.3 3.6 8.2 6.7 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF5133) Zn_clus PF00172.18 OAP59769.1 - 0.014 15.5 5.4 0.028 14.5 5.4 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAP59769.1 - 0.019 14.0 0.1 0.04 12.9 0.1 1.5 1 0 0 1 1 1 0 Fungal specific transcription factor domain MFS_1 PF07690.16 OAP59770.1 - 1.4e-39 136.1 48.8 2.4e-39 135.2 48.8 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 OAP59770.1 - 5.9e-08 31.6 21.9 1.3e-07 30.5 21.9 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Epimerase PF01370.21 OAP59771.1 - 2.8e-20 72.8 0.0 3.7e-20 72.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAP59771.1 - 1.1e-11 44.7 0.0 1.8e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 OAP59771.1 - 3.9e-11 42.5 0.0 5.6e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 OAP59771.1 - 2.5e-10 40.0 0.0 5.9e-10 38.8 0.0 1.6 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 OAP59771.1 - 2.6e-07 30.7 0.0 4.5e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 OAP59771.1 - 5.5e-05 22.7 0.0 0.0002 20.9 0.0 2.1 2 1 0 2 2 2 1 short chain dehydrogenase Polysacc_synt_2 PF02719.15 OAP59771.1 - 0.0001 21.6 0.0 0.00013 21.2 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 OAP59771.1 - 0.00014 21.8 0.0 0.00027 20.9 0.0 1.4 1 0 0 1 1 1 1 KR domain NmrA PF05368.13 OAP59771.1 - 0.0035 16.9 0.0 0.017 14.7 0.0 1.9 2 0 0 2 2 2 1 NmrA-like family adh_short_C2 PF13561.6 OAP59771.1 - 0.056 13.0 0.0 0.22 11.0 0.0 1.9 1 1 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase HHH_5 PF14520.6 OAP59772.1 - 0.019 15.5 0.0 0.027 15.1 0.0 1.2 1 0 0 1 1 1 0 Helix-hairpin-helix domain Cdd1 PF11731.8 OAP59772.1 - 0.029 14.6 0.0 0.12 12.6 0.0 1.9 1 1 1 2 2 2 0 Pathogenicity locus DUF4332 PF14229.6 OAP59772.1 - 0.13 12.6 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4332) Rtf2 PF04641.12 OAP59773.1 - 1.3e-57 195.2 6.3 2e-57 194.6 6.3 1.3 1 1 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.8 OAP59773.1 - 7.5e-07 28.9 0.0 0.0012 18.6 0.0 2.4 1 1 1 2 2 2 2 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 OAP59773.1 - 0.00063 19.7 1.5 0.0032 17.5 0.3 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 OAP59773.1 - 0.0015 18.4 0.2 0.0043 17.0 0.1 1.8 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 OAP59773.1 - 0.011 16.1 0.4 0.052 13.9 0.1 2.2 1 1 1 2 2 2 0 Ring finger domain zf-NOSIP PF15906.5 OAP59773.1 - 0.025 14.7 0.0 0.068 13.3 0.0 1.8 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein ADK_lid PF05191.14 OAP59773.1 - 0.074 13.0 0.8 0.26 11.3 0.4 2.2 3 0 0 3 3 3 0 Adenylate kinase, active site lid zf-C3HC4_3 PF13920.6 OAP59773.1 - 0.14 12.1 0.4 0.35 10.8 0.1 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OAP59773.1 - 0.14 12.0 0.3 0.33 10.8 0.3 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) ADH_zinc_N PF00107.26 OAP59773.1 - 0.16 11.9 0.0 0.33 10.9 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase zf-RING_11 PF17123.5 OAP59773.1 - 0.28 11.0 1.7 0.88 9.4 0.0 2.3 2 0 0 2 2 2 0 RING-like zinc finger MutS_V PF00488.21 OAP59774.1 - 2.2e-70 236.5 0.0 3.8e-70 235.8 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 OAP59774.1 - 2e-39 135.8 8.5 5e-39 134.5 8.5 1.7 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 OAP59774.1 - 2e-19 69.9 0.0 4.7e-19 68.7 0.0 1.6 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 OAP59774.1 - 1.8e-10 41.2 0.0 1.1e-09 38.6 0.0 2.3 2 0 0 2 2 2 1 MutS domain II 3-HAO PF06052.12 OAP59775.1 - 7e-46 155.6 0.0 8.3e-46 155.4 0.0 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Auxin_BP PF02041.16 OAP59775.1 - 0.0027 17.4 0.1 0.0037 16.9 0.1 1.2 1 0 0 1 1 1 1 Auxin binding protein Cupin_2 PF07883.11 OAP59775.1 - 0.0041 16.8 0.1 0.0062 16.2 0.1 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 OAP59775.1 - 0.083 12.8 0.1 0.13 12.1 0.1 1.3 1 0 0 1 1 1 0 AraC-like ligand binding domain RTC_insert PF05189.13 OAP59776.1 - 3e-31 108.0 0.0 6.1e-31 107.0 0.0 1.6 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain RTC PF01137.21 OAP59776.1 - 4.5e-25 88.2 0.0 5.8e-25 87.8 0.0 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase PAP2_3 PF14378.6 OAP59777.1 - 7.7e-32 110.5 19.3 2.8e-16 59.8 0.1 3.5 4 0 0 4 4 4 3 PAP2 superfamily PAP2 PF01569.21 OAP59777.1 - 0.069 12.9 0.2 0.069 12.9 0.2 2.6 2 1 0 2 2 2 0 PAP2 superfamily PWWP PF00855.17 OAP59778.1 - 1.6e-16 60.5 0.0 1.6e-16 60.5 0.0 3.1 2 1 1 3 3 3 1 PWWP domain DNA_mis_repair PF01119.19 OAP59778.1 - 0.0013 18.4 0.0 0.041 13.6 0.0 2.3 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain DUF2935 PF11155.8 OAP59778.1 - 0.054 13.8 0.4 0.11 12.9 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2935) Pkinase PF00069.25 OAP59779.1 - 1e-34 120.1 0.0 2.4e-18 66.5 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAP59779.1 - 1.6e-11 44.0 0.0 0.00078 18.8 0.0 3.7 3 1 0 3 3 3 2 Protein tyrosine kinase APH PF01636.23 OAP59779.1 - 5e-05 23.4 2.0 0.00013 22.0 0.6 2.3 2 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 OAP59779.1 - 0.1 12.2 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase CNDH2_M PF16869.5 OAP59779.1 - 0.27 11.9 4.1 0.27 11.9 1.4 2.1 2 0 0 2 2 2 0 PF16858 Sec63 PF02889.16 OAP59780.1 - 5.4e-162 537.0 0.0 1.9e-92 309.1 0.0 3.0 3 0 0 3 3 3 2 Sec63 Brl domain DEAD PF00270.29 OAP59780.1 - 7e-50 169.2 0.0 5e-28 98.0 0.0 3.0 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_PWI PF18149.1 OAP59780.1 - 5.4e-30 103.8 0.2 1.9e-29 102.1 0.2 2.0 1 0 0 1 1 1 1 N-terminal helicase PWI domain ResIII PF04851.15 OAP59780.1 - 1.9e-24 86.6 0.0 2.2e-14 53.8 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 OAP59780.1 - 3.4e-10 40.3 0.0 1.1e-06 28.9 0.0 3.6 2 1 0 2 2 2 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 OAP59780.1 - 8.2e-08 32.6 0.0 0.00091 19.5 0.0 3.0 2 0 0 2 2 2 2 AAA domain T2SSE PF00437.20 OAP59780.1 - 0.0013 17.8 0.0 0.47 9.5 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein PhoH PF02562.16 OAP59780.1 - 0.0033 16.9 0.0 0.16 11.4 0.0 2.6 2 0 0 2 2 2 1 PhoH-like protein AAA_19 PF13245.6 OAP59780.1 - 0.02 15.2 0.2 13 6.1 0.0 3.4 3 0 0 3 3 3 0 AAA domain Helicase_C_2 PF13307.6 OAP59780.1 - 0.083 13.0 0.0 21 5.2 0.0 3.5 4 0 0 4 4 4 0 Helicase C-terminal domain Acetyltransf_1 PF00583.25 OAP59781.1 - 0.059 13.6 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family FR47 PF08445.10 OAP59781.1 - 0.085 12.8 0.0 0.28 11.2 0.0 1.8 1 0 0 1 1 1 0 FR47-like protein Thiolase_N PF00108.23 OAP59782.1 - 1.3e-74 250.9 0.5 1.7e-74 250.4 0.5 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 OAP59782.1 - 3.4e-41 139.8 0.2 8.9e-41 138.4 0.2 1.7 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 OAP59782.1 - 0.00096 18.8 1.6 0.0027 17.3 0.7 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 OAP59782.1 - 0.19 11.6 1.0 8.1 6.4 0.2 2.4 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Ribosomal_L50 PF10501.9 OAP59783.1 - 1.8e-05 24.9 0.1 4.1e-05 23.7 0.1 1.7 1 0 0 1 1 1 1 Ribosomal subunit 39S Methyltransf_16 PF10294.9 OAP59784.1 - 2.2e-20 73.1 0.0 3.5e-20 72.5 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 OAP59784.1 - 0.0004 20.3 0.0 0.00055 19.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAP59784.1 - 0.17 12.6 0.0 0.67 10.7 0.0 2.1 2 1 0 2 2 2 0 Methyltransferase domain MFS_1 PF07690.16 OAP59785.1 - 3.3e-34 118.4 29.9 3.5e-34 118.3 29.0 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Fungal_trans_2 PF11951.8 OAP59786.1 - 0.0027 16.6 0.0 0.0045 15.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF899 PF05988.12 OAP59787.1 - 1.1e-72 244.1 0.0 1.4e-72 243.8 0.0 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF899) AKAP2_C PF15304.6 OAP59787.1 - 0.22 10.8 0.1 0.32 10.3 0.1 1.1 1 0 0 1 1 1 0 A-kinase anchor protein 2 C-terminus p450 PF00067.22 OAP59788.1 - 4.7e-60 203.6 0.0 5.8e-60 203.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PhzC-PhzF PF02567.16 OAP59790.1 - 2.7e-18 66.4 0.1 1.3e-15 57.6 0.0 2.4 1 1 1 2 2 2 2 Phenazine biosynthesis-like protein Zn_clus PF00172.18 OAP59790.1 - 1.4e-08 34.7 7.6 4.3e-08 33.2 7.6 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ank_5 PF13857.6 OAP59791.1 - 8.9e-05 22.7 0.0 0.0002 21.6 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) polyprenyl_synt PF00348.17 OAP59792.1 - 3e-71 239.5 0.0 1.7e-70 237.0 0.0 1.9 1 1 0 1 1 1 1 Polyprenyl synthetase HEPPP_synt_1 PF07307.11 OAP59792.1 - 0.12 12.0 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 AMMECR1 PF01871.17 OAP59793.1 - 3.4e-40 137.4 0.0 6.6e-40 136.4 0.0 1.4 1 0 0 1 1 1 1 AMMECR1 Apt1 PF10351.9 OAP59793.1 - 0.0028 16.6 3.3 0.0028 16.6 3.3 1.1 1 0 0 1 1 1 1 Golgi-body localisation protein domain YL1 PF05764.13 OAP59793.1 - 0.029 14.5 11.2 0.044 13.9 11.2 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Peptidase_S64 PF08192.11 OAP59793.1 - 0.11 11.0 12.5 0.14 10.6 12.5 1.0 1 0 0 1 1 1 0 Peptidase family S64 PI3K_1B_p101 PF10486.9 OAP59793.1 - 0.39 8.4 13.1 0.53 8.0 13.1 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Astro_capsid_p PF12226.8 OAP59793.1 - 0.52 9.4 5.5 0.83 8.7 5.5 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein BUD22 PF09073.10 OAP59793.1 - 0.77 9.0 19.0 1.2 8.4 19.0 1.3 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 OAP59793.1 - 0.99 7.5 10.4 1.3 7.2 10.4 1.1 1 0 0 1 1 1 0 Nop14-like family ORC_WH_C PF18137.1 OAP59793.1 - 2 8.5 6.5 0.22 11.6 2.2 1.6 2 0 0 2 2 2 0 Origin recognition complex winged helix C-terminal SPX PF03105.19 OAP59793.1 - 2.3 8.1 15.2 3.7 7.4 15.2 1.2 1 0 0 1 1 1 0 SPX domain Macoilin PF09726.9 OAP59793.1 - 2.5 6.5 10.2 3.2 6.2 10.2 1.1 1 0 0 1 1 1 0 Macoilin family CDC45 PF02724.14 OAP59793.1 - 3.3 5.9 10.8 4.4 5.5 10.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Sporozoite_P67 PF05642.11 OAP59793.1 - 4.9 5.1 10.2 8.7 4.3 10.2 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Ank_4 PF13637.6 OAP59794.1 - 2.6e-24 85.3 7.1 2.2e-08 34.5 0.1 5.3 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 OAP59794.1 - 6.7e-23 81.1 0.1 3.3e-07 30.8 0.0 3.2 3 0 0 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 OAP59794.1 - 1.9e-20 72.3 2.7 9.9e-05 22.6 0.1 4.5 4 1 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 OAP59794.1 - 8e-20 70.6 0.7 4.2e-06 26.9 0.1 4.2 3 2 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAP59794.1 - 4.4e-18 63.5 1.4 0.004 17.5 0.1 6.0 6 0 0 6 6 6 4 Ankyrin repeat adh_short PF00106.25 OAP59795.1 - 2e-38 131.8 0.0 2.8e-38 131.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP59795.1 - 1.5e-22 80.4 0.0 1.9e-22 80.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP59795.1 - 2.7e-05 24.1 0.1 8.7e-05 22.5 0.1 1.9 1 1 0 1 1 1 1 KR domain Erg28 PF03694.13 OAP59796.1 - 1.7e-36 125.0 0.2 2e-36 124.7 0.2 1.1 1 0 0 1 1 1 1 Erg28 like protein Cellsynth_D PF03500.13 OAP59796.1 - 0.17 11.8 0.1 0.29 11.0 0.1 1.3 1 1 0 1 1 1 0 Cellulose synthase subunit D GalP_UDP_transf PF01087.22 OAP59797.1 - 7e-69 231.9 0.0 1.1e-67 228.1 0.0 2.2 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.17 OAP59797.1 - 2.2e-59 200.0 0.0 4.5e-59 198.9 0.0 1.4 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain HIT PF01230.23 OAP59797.1 - 0.0018 18.9 0.0 0.0061 17.3 0.0 1.8 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.8 OAP59797.1 - 0.029 14.8 0.0 0.066 13.7 0.0 1.5 1 0 0 1 1 1 0 Scavenger mRNA decapping enzyme C-term binding WG_beta_rep PF14903.6 OAP59797.1 - 0.16 12.3 0.1 0.43 10.9 0.1 1.6 1 0 0 1 1 1 0 WG containing repeat F-box-like PF12937.7 OAP59798.1 - 4.3e-08 32.9 0.5 8.9e-08 31.9 0.5 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAP59798.1 - 0.00092 19.0 1.9 0.00092 19.0 1.9 1.7 2 0 0 2 2 2 1 F-box domain Clr5 PF14420.6 OAP59800.1 - 2.2e-14 53.4 0.3 7.9e-14 51.6 0.3 2.0 1 0 0 1 1 1 1 Clr5 domain HTH_33 PF13592.6 OAP59800.1 - 0.044 13.4 0.1 0.14 11.8 0.1 1.9 1 0 0 1 1 1 0 Winged helix-turn helix APH PF01636.23 OAP59802.1 - 7.1e-10 39.2 0.2 1.2e-09 38.4 0.2 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Glyco_hydro_47 PF01532.20 OAP59804.1 - 2e-110 369.8 0.0 2.9e-110 369.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 3Beta_HSD PF01073.19 OAP59805.1 - 1e-14 54.3 0.0 1.3e-14 53.8 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 OAP59805.1 - 1.1e-13 51.2 0.1 2e-13 50.4 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 OAP59805.1 - 1.5e-10 40.7 0.0 0.00023 20.4 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 OAP59805.1 - 6.1e-07 29.5 0.0 1.5e-06 28.3 0.0 1.6 2 0 0 2 2 2 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 OAP59805.1 - 1.8e-06 27.6 0.0 3.4e-06 26.7 0.0 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase KR PF08659.10 OAP59805.1 - 1.2e-05 25.3 0.0 3.9e-05 23.6 0.0 1.8 2 0 0 2 2 2 1 KR domain adh_short PF00106.25 OAP59805.1 - 0.0051 16.3 0.9 0.035 13.6 0.0 2.6 3 1 0 3 3 3 1 short chain dehydrogenase NmrA PF05368.13 OAP59805.1 - 0.017 14.7 0.0 0.037 13.6 0.0 1.6 2 0 0 2 2 2 0 NmrA-like family Fungal_trans PF04082.18 OAP59806.1 - 1.3e-14 53.9 0.4 1.8e-14 53.4 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP59806.1 - 3.6e-05 23.8 13.6 6.5e-05 23.0 13.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAP59807.1 - 4.4e-21 75.1 0.1 7.1e-21 74.4 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP59807.1 - 7.8e-07 29.1 13.4 1.5e-06 28.2 13.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_12 PF13424.6 OAP59807.1 - 0.081 13.2 0.0 0.21 11.9 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF1127 PF06568.11 OAP59807.1 - 0.11 12.2 0.3 0.42 10.4 0.3 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1127) PAC4 PF16093.5 OAP59808.1 - 2.2e-19 69.4 0.1 2.9e-19 69.0 0.1 1.2 1 0 0 1 1 1 1 Proteasome assembly chaperone 4 POC3_POC4 PF10448.9 OAP59808.1 - 0.017 15.2 0.0 0.017 15.1 0.0 1.1 1 0 0 1 1 1 0 20S proteasome chaperone assembly proteins 3 and 4 N2227 PF07942.12 OAP59809.1 - 1.3e-85 286.9 0.0 1.6e-85 286.6 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_11 PF08241.12 OAP59809.1 - 0.0054 17.4 0.0 0.47 11.1 0.0 2.5 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAP59809.1 - 0.015 15.1 0.0 0.038 13.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 OAP59809.1 - 0.019 15.7 0.0 0.77 10.5 0.0 2.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 OAP59809.1 - 0.16 12.7 0.0 4.5 8.0 0.0 2.4 1 1 1 2 2 2 0 Methyltransferase domain HSP70 PF00012.20 OAP59810.1 - 5e-11 41.5 0.5 1.7e-09 36.4 0.2 2.0 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 OAP59810.1 - 0.061 12.1 0.1 0.27 10.0 0.0 1.8 2 0 0 2 2 2 0 MreB/Mbl protein HSP70 PF00012.20 OAP59811.1 - 7.6e-61 206.0 1.5 9.1e-57 192.6 0.2 2.6 2 1 1 3 3 3 2 Hsp70 protein MreB_Mbl PF06723.13 OAP59811.1 - 0.016 14.1 0.0 0.036 12.9 0.0 1.6 1 0 0 1 1 1 0 MreB/Mbl protein AbiEi_3_N PF17194.4 OAP59811.1 - 0.017 15.2 0.0 0.045 13.8 0.0 1.7 1 0 0 1 1 1 0 Transcriptional regulator, AbiEi antitoxin N-terminal domain YkyA PF10368.9 OAP59811.1 - 0.25 11.0 2.0 0.66 9.6 2.0 1.7 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein Tubulin_3 PF14881.6 OAP59812.1 - 8.5e-77 256.9 0.2 4.3e-76 254.6 0.2 2.1 3 0 0 3 3 3 1 Tubulin domain Misat_Tub_SegII PF10644.9 OAP59812.1 - 6.3e-39 132.9 0.0 1.8e-38 131.5 0.0 1.8 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin PF00091.25 OAP59812.1 - 0.0036 17.5 0.0 0.52 10.5 0.0 2.3 2 0 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain NPR1_interact PF15699.5 OAP59813.1 - 1.6 9.4 18.3 17 6.1 1.1 4.2 1 1 1 2 2 2 0 NPR1 interacting DUF1479 PF07350.12 OAP59814.1 - 1.6e-120 402.6 0.0 1.9e-120 402.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) Sugar_tr PF00083.24 OAP59815.1 - 1.8e-79 267.8 26.3 2.2e-79 267.5 26.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP59815.1 - 2.2e-21 76.2 33.9 2.2e-21 76.2 33.9 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4410 PF14366.6 OAP59815.1 - 0.14 12.1 0.1 0.42 10.5 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4410) Pilin_N PF07790.11 OAP59815.1 - 0.2 12.6 2.0 0.58 11.1 2.0 1.9 1 0 0 1 1 1 0 Archaeal Type IV pilin, N-terminal Fungal_trans PF04082.18 OAP59816.1 - 8e-14 51.3 0.0 1.3e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP59816.1 - 0.0082 16.2 2.2 0.015 15.4 2.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PMI_typeI PF01238.21 OAP59817.1 - 9.2e-73 245.6 0.0 2.1e-72 244.4 0.0 1.5 1 1 0 1 1 1 1 Phosphomannose isomerase type I AraC_binding PF02311.19 OAP59817.1 - 3.7e-05 23.6 0.1 0.00047 20.1 0.0 2.7 3 0 0 3 3 3 1 AraC-like ligand binding domain Cupin_2 PF07883.11 OAP59817.1 - 0.00077 19.1 0.1 0.053 13.3 0.1 2.3 2 0 0 2 2 2 1 Cupin domain AraC_N PF06719.13 OAP59817.1 - 0.026 14.2 0.1 0.064 12.9 0.0 1.6 2 0 0 2 2 2 0 AraC-type transcriptional regulator N-terminus Cupin_3 PF05899.12 OAP59817.1 - 0.17 11.6 0.5 0.38 10.5 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF861) UPF0242 PF06785.11 OAP59818.1 - 0.031 14.4 13.1 0.99 9.5 5.4 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus C1_2 PF03107.16 OAP59818.1 - 0.034 14.5 4.9 0.09 13.1 4.9 1.7 1 0 0 1 1 1 0 C1 domain LpqV PF17301.2 OAP59818.1 - 0.22 11.8 0.1 0.22 11.8 0.1 2.8 3 0 0 3 3 3 0 Putative lipoprotein LpqV Siva PF05458.12 OAP59818.1 - 0.25 11.0 4.0 0.85 9.3 4.0 1.9 1 0 0 1 1 1 0 Cd27 binding protein (Siva) SAGA-Tad1 PF12767.7 OAP59818.1 - 1.8 8.3 12.0 1.3 8.7 0.9 2.7 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit zf-UBR PF02207.20 OAP59818.1 - 8.9 6.6 12.4 0.17 12.1 2.9 2.3 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) CoA_binding_2 PF13380.6 OAP59819.1 - 8.3e-25 87.5 0.0 9.7e-25 87.3 0.0 1.1 1 0 0 1 1 1 1 CoA binding domain AA_permease PF00324.21 OAP59822.1 - 7.6e-95 318.3 42.9 9.2e-95 318.0 42.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAP59822.1 - 3.8e-24 85.3 46.8 4.5e-24 85.1 46.8 1.0 1 0 0 1 1 1 1 Amino acid permease Ribosomal_S15 PF00312.22 OAP59822.1 - 0.26 11.5 0.1 0.46 10.7 0.1 1.3 1 0 0 1 1 1 0 Ribosomal protein S15 PEP_mutase PF13714.6 OAP59823.1 - 3e-58 197.1 2.2 3.5e-58 196.9 2.2 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase DUF3253 PF11625.8 OAP59823.1 - 0.1 12.8 0.2 14 6.0 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3253) Fungal_trans_2 PF11951.8 OAP59824.1 - 4.3e-10 39.0 2.6 4.6e-10 38.9 1.2 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain TANGO2 PF05742.12 OAP59825.1 - 9.4e-70 235.5 0.0 1.1e-69 235.3 0.0 1.0 1 0 0 1 1 1 1 Transport and Golgi organisation 2 TB2_DP1_HVA22 PF03134.19 OAP59826.1 - 2.2e-22 78.8 7.2 4e-22 77.9 7.2 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family zf-RING_2 PF13639.6 OAP59827.1 - 2.4e-13 50.2 4.4 4.2e-13 49.4 4.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 OAP59827.1 - 2.9e-11 42.9 1.5 5.7e-11 42.0 1.5 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 OAP59827.1 - 1.4e-07 31.3 4.2 2.2e-07 30.6 4.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OAP59827.1 - 9.2e-07 29.1 4.5 2.3e-06 27.8 4.5 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 OAP59827.1 - 9.6e-07 28.6 3.7 1.6e-06 27.8 3.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAP59827.1 - 1.7e-05 24.7 2.3 3e-05 23.9 2.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 OAP59827.1 - 1.8e-05 24.5 5.2 3.5e-05 23.6 5.2 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 OAP59827.1 - 0.0011 19.0 3.9 0.002 18.1 3.9 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 OAP59827.1 - 0.0039 17.0 2.3 0.0075 16.1 2.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 OAP59827.1 - 0.0057 16.7 1.4 0.012 15.6 1.4 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 OAP59827.1 - 0.023 14.5 3.2 0.039 13.7 3.2 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.29 OAP59827.1 - 0.042 13.7 2.9 0.077 12.9 2.9 1.5 1 0 0 1 1 1 0 PHD-finger zf-RING-like PF08746.11 OAP59827.1 - 0.063 13.6 2.1 0.11 12.8 2.1 1.5 1 0 0 1 1 1 0 RING-like domain zf-C3H2C3 PF17122.5 OAP59827.1 - 0.2 11.7 1.8 0.47 10.5 1.8 1.6 1 0 0 1 1 1 0 Zinc-finger Zn_ribbon_17 PF17120.5 OAP59827.1 - 0.4 10.3 2.3 0.75 9.5 2.3 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 OAP59827.1 - 0.98 9.6 3.9 4.9 7.4 3.9 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain DUF1180 PF06679.12 OAP59827.1 - 1.5 9.2 0.0 1.5 9.2 0.0 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF1180) K_oxygenase PF13434.6 OAP59829.1 - 0.00037 19.8 0.0 0.00051 19.3 0.0 1.1 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 OAP59829.1 - 0.15 11.3 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SLATT_fungal PF18142.1 OAP59830.1 - 0.36 10.8 2.1 0.61 10.1 2.1 1.4 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain DUF4407 PF14362.6 OAP59830.1 - 9 5.5 8.4 15 4.8 8.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FA_desaturase PF00487.24 OAP59831.1 - 5.5e-20 72.3 13.2 5.5e-20 72.3 13.2 1.7 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.28 OAP59831.1 - 1.2e-16 60.6 0.1 3e-16 59.3 0.1 1.7 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain U-box PF04564.15 OAP59832.1 - 2.5e-22 78.8 0.1 6.2e-22 77.6 0.0 1.7 2 0 0 2 2 1 1 U-box domain TPR_2 PF07719.17 OAP59832.1 - 4.7e-09 35.7 9.7 0.017 15.2 0.4 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 OAP59832.1 - 4.4e-05 24.0 7.2 0.0046 17.6 0.6 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 OAP59832.1 - 5.5e-05 22.8 5.9 0.0027 17.5 0.2 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 OAP59832.1 - 0.00061 20.0 12.2 0.073 13.4 2.9 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat Lyase_aromatic PF00221.19 OAP59832.1 - 0.0017 17.1 0.4 0.0022 16.7 0.4 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase TPR_10 PF13374.6 OAP59832.1 - 0.0023 17.8 14.5 0.16 11.9 0.1 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 OAP59832.1 - 0.0098 16.1 5.3 0.38 11.0 0.7 3.0 1 1 2 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 CHIP_TPR_N PF18391.1 OAP59832.1 - 0.043 14.6 7.6 0.093 13.5 7.6 1.5 1 0 0 1 1 1 0 CHIP N-terminal tetratricopeptide repeat domain zf-NOSIP PF15906.5 OAP59832.1 - 0.048 13.8 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein TPR_19 PF14559.6 OAP59832.1 - 0.087 13.3 6.2 1.1 9.8 0.8 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 OAP59832.1 - 0.11 12.6 0.0 0.11 12.6 0.0 3.7 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 OAP59832.1 - 0.19 12.2 2.7 4.3 7.9 0.3 3.6 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 OAP59832.1 - 0.31 12.0 11.2 2.3 9.2 0.1 3.9 2 2 2 4 4 4 0 Tetratricopeptide repeat DUF2526 PF10735.9 OAP59832.1 - 0.33 11.2 5.8 0.55 10.4 3.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2526) TPR_6 PF13174.6 OAP59832.1 - 1 10.1 4.9 22 5.9 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 OAP59832.1 - 1.1 8.9 5.4 0.6 9.8 0.6 2.5 2 0 0 2 2 2 0 TPR repeat ACBP PF00887.19 OAP59833.1 - 2.6e-21 75.6 1.2 3e-21 75.4 1.2 1.1 1 0 0 1 1 1 1 Acyl CoA binding protein WD40 PF00400.32 OAP59834.1 - 5.1e-09 36.6 7.2 0.071 14.0 0.4 4.9 4 0 0 4 4 4 3 WD domain, G-beta repeat WD40_3 PF15911.5 OAP59834.1 - 0.0056 16.6 0.0 2.3 8.3 0.0 3.1 3 0 0 3 3 3 1 WD domain, G-beta repeat SOG2 PF10428.9 OAP59834.1 - 0.062 12.5 8.7 0.085 12.0 8.7 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein PPP4R2 PF09184.11 OAP59834.1 - 0.14 11.8 2.7 0.21 11.2 2.7 1.2 1 0 0 1 1 1 0 PPP4R2 Ge1_WD40 PF16529.5 OAP59834.1 - 0.16 10.9 0.0 0.94 8.4 0.0 2.2 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Apt1 PF10351.9 OAP59834.1 - 0.72 8.6 4.3 1 8.2 4.3 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Spt20 PF12090.8 OAP59834.1 - 5.5 6.5 15.1 8.8 5.9 15.1 1.2 1 0 0 1 1 1 0 Spt20 family BES1_N PF05687.13 OAP59834.1 - 6.1 7.2 8.7 10 6.5 8.7 1.3 1 0 0 1 1 1 0 BES1/BZR1 plant transcription factor, N-terminal Glycos_transf_4 PF00953.21 OAP59835.1 - 2.2e-32 112.2 9.1 2.2e-32 112.2 9.1 2.6 2 1 0 2 2 2 1 Glycosyl transferase family 4 Tyr-DNA_phospho PF06087.12 OAP59836.1 - 2.9e-139 464.6 0.0 3.4e-139 464.4 0.0 1.0 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.6 OAP59836.1 - 0.00092 19.1 0.0 0.39 10.6 0.0 2.2 2 0 0 2 2 2 2 PLD-like domain DUF4290 PF14123.6 OAP59836.1 - 0.22 11.1 0.0 0.47 10.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4290) Rad4 PF03835.15 OAP59837.1 - 5.9e-34 116.9 0.1 2e-33 115.2 0.1 1.9 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.9 OAP59837.1 - 9.7e-29 99.6 0.3 1.8e-28 98.7 0.3 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 OAP59837.1 - 1e-15 57.3 0.1 2.4e-15 56.1 0.1 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 OAP59837.1 - 1.5e-14 54.7 1.6 1.5e-14 54.7 1.6 3.8 3 0 0 3 3 3 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.19 OAP59837.1 - 0.0017 18.8 0.0 0.0083 16.6 0.0 2.2 2 0 0 2 2 2 1 Transglutaminase-like superfamily EF-hand_7 PF13499.6 OAP59838.1 - 9.9e-13 48.3 0.2 1.4e-07 31.8 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 OAP59838.1 - 9.1e-10 38.7 0.0 0.00053 20.3 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_6 PF13405.6 OAP59838.1 - 1.2e-09 37.4 0.1 0.0087 15.9 0.0 3.4 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 OAP59838.1 - 2e-09 36.3 0.0 0.027 14.0 0.0 3.6 3 1 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 OAP59838.1 - 6e-07 29.2 0.1 2.6e-05 24.0 0.1 2.8 3 0 0 3 3 3 1 EF-hand domain pair DUF3216 PF11505.8 OAP59838.1 - 0.066 13.4 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3216) 2OG-FeII_Oxy PF03171.20 OAP59839.1 - 1.2e-17 64.2 0.0 2.3e-17 63.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 OAP59839.1 - 4.9e-17 62.8 0.0 1.6e-11 45.0 0.0 2.4 2 0 0 2 2 2 2 non-haem dioxygenase in morphine synthesis N-terminal Transp_cyt_pur PF02133.15 OAP59840.1 - 9.3e-34 116.9 28.3 1.2e-33 116.6 28.3 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin AA_permease_2 PF13520.6 OAP59841.1 - 1.7e-40 139.1 55.2 2.1e-40 138.8 55.2 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAP59841.1 - 3.4e-17 62.2 44.6 4.9e-17 61.7 44.6 1.1 1 0 0 1 1 1 1 Amino acid permease Peptidase_M13_N PF05649.13 OAP59842.1 - 9.6e-95 318.5 0.0 1.6e-94 317.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 OAP59842.1 - 1.6e-62 210.8 0.1 2.6e-62 210.1 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M13 PSII_Pbs27 PF13326.6 OAP59842.1 - 0.073 13.4 2.6 0.65 10.3 0.1 3.0 2 1 1 3 3 3 0 Photosystem II Pbs27 DUF3306 PF11748.8 OAP59842.1 - 0.22 12.4 1.3 12 6.8 0.8 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) SET PF00856.28 OAP59843.1 - 0.059 13.8 0.0 2 8.8 0.0 2.5 1 1 0 1 1 1 0 SET domain p450 PF00067.22 OAP59844.1 - 2.1e-31 109.2 0.0 3.2e-31 108.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 DUF4131 PF13567.6 OAP59844.1 - 0.047 13.4 0.7 0.078 12.6 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) HATPase_c PF02518.26 OAP59846.1 - 1.2e-25 90.2 0.0 3.2e-25 88.8 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 OAP59846.1 - 1.7e-25 89.4 0.4 5.1e-25 87.8 0.4 1.9 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 OAP59846.1 - 2e-16 59.7 1.6 3.1e-16 59.2 0.2 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.10 OAP59846.1 - 9e-16 58.1 0.0 7.5e-07 29.4 0.0 2.3 2 0 0 2 2 2 2 PAS fold PAS PF00989.25 OAP59846.1 - 2.3e-12 46.9 0.0 1.5e-08 34.7 0.0 2.7 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 OAP59846.1 - 8.3e-12 45.3 0.0 3.5e-11 43.3 0.0 2.1 2 0 0 2 2 2 1 PAS domain DUF5601 PF18151.1 OAP59846.1 - 0.17 12.2 0.0 2.3 8.6 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5601) H_kinase_N PF12282.8 OAP59846.1 - 0.17 11.8 0.4 24 4.8 0.1 2.3 2 0 0 2 2 2 0 Signal transduction histidine kinase Acetyltransf_1 PF00583.25 OAP59848.1 - 1.2e-12 48.1 0.0 2.8e-12 46.9 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OAP59848.1 - 1.8e-10 40.8 0.0 2.8e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OAP59848.1 - 1.8e-06 28.3 0.0 2.9e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 OAP59848.1 - 0.0015 18.6 0.0 0.17 11.9 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAP59848.1 - 0.035 14.1 0.0 0.07 13.1 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein SDA1 PF05285.12 OAP59848.1 - 1.8 7.9 5.9 2.7 7.4 5.9 1.2 1 0 0 1 1 1 0 SDA1 Asp_protease PF09668.10 OAP59849.1 - 1.5e-57 192.8 0.1 2.4e-57 192.1 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 OAP59849.1 - 2.5e-22 79.2 0.1 6.8e-22 77.8 0.1 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 OAP59849.1 - 1.3e-11 45.0 1.8 2.8e-11 43.9 0.2 2.3 2 0 0 2 2 2 1 Aspartyl protease UBA PF00627.31 OAP59849.1 - 6.1e-09 35.6 0.1 1.2e-08 34.7 0.1 1.5 1 0 0 1 1 1 1 UBA/TS-N domain ubiquitin PF00240.23 OAP59849.1 - 1.4e-05 24.8 0.0 2.5e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family RVP_2 PF08284.11 OAP59849.1 - 3.3e-05 23.7 0.1 0.00044 20.0 0.0 2.3 2 1 0 2 2 2 1 Retroviral aspartyl protease RVP PF00077.20 OAP59849.1 - 0.00034 20.9 0.0 0.00075 19.8 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease UBA_4 PF14555.6 OAP59849.1 - 0.011 15.5 0.0 0.028 14.2 0.0 1.6 1 0 0 1 1 1 0 UBA-like domain CUE PF02845.16 OAP59849.1 - 0.038 13.7 0.0 0.14 11.9 0.0 2.0 2 0 0 2 2 2 0 CUE domain NOT2_3_5 PF04153.18 OAP59850.1 - 1.7e-25 89.6 0.3 4e-25 88.4 0.3 1.6 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family ATG16 PF08614.11 OAP59851.1 - 0.0052 17.0 3.8 0.0052 17.0 3.8 2.2 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) NPV_P10 PF05531.12 OAP59851.1 - 0.025 15.0 0.3 2.4 8.7 0.3 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein MscS_porin PF12795.7 OAP59851.1 - 0.025 14.1 7.8 0.088 12.3 7.5 1.8 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain BRE1 PF08647.11 OAP59851.1 - 0.089 12.9 3.1 1.4 9.0 0.3 2.6 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase DUF4686 PF15742.5 OAP59851.1 - 0.16 11.1 8.9 0.24 10.5 8.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4686) CENP-F_leu_zip PF10473.9 OAP59851.1 - 0.36 10.8 7.7 0.17 11.9 0.4 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FAP206 PF12018.8 OAP59851.1 - 0.37 10.3 4.4 0.58 9.6 4.4 1.3 1 0 0 1 1 1 0 Domain of unknown function Exonuc_VII_L PF02601.15 OAP59851.1 - 0.44 10.1 4.0 0.82 9.2 4.0 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit HAUS-augmin3 PF14932.6 OAP59851.1 - 0.84 9.2 7.2 1.4 8.5 7.2 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 FOXP-CC PF16159.5 OAP59851.1 - 2.2 9.0 3.6 7.8 7.2 0.5 3.1 2 1 2 4 4 4 0 FOXP coiled-coil domain dCMP_cyt_deam_1 PF00383.23 OAP59852.1 - 1.6e-07 31.1 0.0 3.5e-07 30.0 0.0 1.6 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 OAP59852.1 - 1.7e-05 24.6 0.0 0.0007 19.4 0.0 2.2 2 0 0 2 2 2 1 MafB19-like deaminase Bd3614-deam PF14439.6 OAP59852.1 - 0.1 12.7 0.1 0.21 11.7 0.1 1.5 1 0 0 1 1 1 0 Bd3614-like deaminase Pribosyltran PF00156.27 OAP59853.1 - 1.6e-16 60.2 0.3 2.4e-16 59.6 0.3 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain MTHFR PF02219.17 OAP59854.1 - 7.1e-115 383.2 0.0 9.6e-115 382.8 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase CENP-F_N PF10481.9 OAP59855.1 - 9 5.8 7.6 6.7 6.3 4.9 2.0 2 0 0 2 2 2 0 Cenp-F N-terminal domain Hexokinase_2 PF03727.16 OAP59856.1 - 3.2e-54 183.9 0.0 5.9e-54 183.0 0.0 1.4 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 OAP59856.1 - 1.3e-46 159.1 0.0 1.8e-46 158.5 0.0 1.2 1 0 0 1 1 1 1 Hexokinase FAA_hydrolase PF01557.18 OAP59858.1 - 1.4e-49 168.7 0.0 1.7e-49 168.5 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Not3 PF04065.15 OAP59859.1 - 0.0023 17.4 0.6 0.0046 16.4 0.6 1.5 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component ALMT PF11744.8 OAP59859.1 - 1.1 8.0 4.5 2.2 7.0 4.5 1.4 1 0 0 1 1 1 0 Aluminium activated malate transporter Csm1_N PF18504.1 OAP59859.1 - 3.7 7.9 9.4 0.091 13.1 1.2 2.5 2 0 0 2 2 2 0 Csm1 N-terminal domain DEAD PF00270.29 OAP59860.1 - 1.1e-44 152.3 0.6 2e-44 151.4 0.6 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAP59860.1 - 6.1e-32 110.3 0.3 4.1e-31 107.6 0.1 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAP59860.1 - 1.8e-06 28.1 0.0 2.9e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 OAP59860.1 - 0.00049 19.9 0.0 0.00091 19.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OAP59860.1 - 0.0014 19.0 0.4 0.012 15.9 0.2 2.2 2 1 0 2 2 2 1 AAA domain CMS1 PF14617.6 OAP59860.1 - 0.0065 15.8 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit AAA_22 PF13401.6 OAP59860.1 - 0.051 13.9 1.7 0.4 11.0 1.7 2.4 1 1 0 1 1 1 0 AAA domain IL17R_D_N PF16742.5 OAP59860.1 - 0.097 12.7 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 N-terminus of interleukin 17 receptor D fragilysinNterm PF16376.5 OAP59860.1 - 0.11 12.2 0.0 0.32 10.7 0.0 1.7 1 0 0 1 1 1 0 N-terminal domain of fragilysin Helicase_RecD PF05127.14 OAP59860.1 - 0.13 12.1 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 Helicase Cupin_8 PF13621.6 OAP59861.1 - 9.8e-16 58.2 0.9 4.2e-14 52.9 0.1 2.6 2 1 0 2 2 2 1 Cupin-like domain JmjC PF02373.22 OAP59861.1 - 2.4e-10 40.8 0.1 6.9e-10 39.4 0.1 1.8 1 1 0 1 1 1 1 JmjC domain, hydroxylase F-box-like PF12937.7 OAP59861.1 - 1.2e-05 25.1 0.1 2.7e-05 24.0 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAP59861.1 - 3.8e-05 23.4 0.1 0.00011 21.9 0.0 1.9 2 0 0 2 2 2 1 F-box domain DUF3460 PF11943.8 OAP59861.1 - 0.077 13.3 0.3 0.32 11.3 0.3 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3460) Ctr PF04145.15 OAP59862.1 - 2.4e-27 96.4 5.4 4e-27 95.6 5.4 1.3 1 1 0 1 1 1 1 Ctr copper transporter family TspO_MBR PF03073.15 OAP59862.1 - 0.16 12.1 5.4 0.18 11.8 3.7 1.8 1 1 1 2 2 2 0 TspO/MBR family NuA4 PF09340.10 OAP59863.1 - 4.1e-27 93.9 1.1 7e-27 93.1 0.0 1.9 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 NUDIX PF00293.28 OAP59864.1 - 8.5e-12 45.2 0.1 2.8e-11 43.6 0.0 1.9 1 1 1 2 2 2 1 NUDIX domain PHINT_rpt PF14882.6 OAP59864.1 - 0.063 13.6 2.8 0.18 12.1 2.8 1.7 1 0 0 1 1 1 0 Phage-integrase repeat unit Glyco_hydro_38N PF01074.22 OAP59866.1 - 6.9e-88 294.7 1.3 6.9e-88 294.7 1.3 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 OAP59866.1 - 1.7e-58 198.3 0.1 1.1e-57 195.6 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 OAP59866.1 - 4.5e-27 94.0 0.1 1e-26 92.9 0.1 1.7 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 OAP59866.1 - 1.4e-11 44.3 0.0 3.6e-11 43.0 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain CAP_GLY PF01302.25 OAP59867.1 - 2.8e-16 59.3 0.2 5.8e-16 58.3 0.2 1.6 1 0 0 1 1 1 1 CAP-Gly domain CLIP1_ZNF PF16641.5 OAP59867.1 - 3.9e-08 33.0 11.9 0.00045 20.0 1.3 2.5 2 0 0 2 2 2 2 CLIP1 zinc knuckle DUF812 PF05667.11 OAP59867.1 - 6.1e-05 22.1 16.6 6.1e-05 22.1 16.6 2.4 1 1 1 2 2 2 1 Protein of unknown function (DUF812) EzrA PF06160.12 OAP59867.1 - 0.0016 16.7 19.6 0.01 14.0 19.0 2.3 1 1 0 1 1 1 1 Septation ring formation regulator, EzrA Fez1 PF06818.15 OAP59867.1 - 0.0029 18.1 32.6 0.15 12.5 17.0 3.1 2 1 0 3 3 3 2 Fez1 AAA_13 PF13166.6 OAP59867.1 - 0.003 16.3 8.9 0.003 16.3 8.9 2.9 2 1 0 3 3 3 1 AAA domain PKcGMP_CC PF16808.5 OAP59867.1 - 0.016 15.0 0.1 0.016 15.0 0.1 4.9 5 1 0 5 5 5 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Spc7 PF08317.11 OAP59867.1 - 0.016 14.1 33.9 0.05 12.5 12.8 3.2 2 1 1 3 3 3 0 Spc7 kinetochore protein DUF5339 PF17274.2 OAP59867.1 - 0.059 14.2 4.2 5.8 7.8 0.3 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5339) Paramyx_P_V_C PF03210.13 OAP59867.1 - 0.06 13.1 0.7 0.12 12.1 0.0 1.9 2 0 0 2 2 1 0 Paramyxovirus P/V phosphoprotein C-terminal DUF1664 PF07889.12 OAP59867.1 - 0.17 11.9 17.7 0.24 11.4 3.9 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF1664) DUF241 PF03087.14 OAP59867.1 - 0.21 11.4 11.0 0.16 11.8 5.1 2.6 1 1 1 2 2 2 0 Arabidopsis protein of unknown function DELLA PF12041.8 OAP59867.1 - 0.24 11.3 0.8 0.72 9.8 0.8 1.8 1 0 0 1 1 1 0 Transcriptional regulator DELLA protein N terminal NPV_P10 PF05531.12 OAP59867.1 - 0.3 11.6 21.5 0.19 12.2 3.3 4.6 4 1 1 5 5 5 0 Nucleopolyhedrovirus P10 protein DUF3584 PF12128.8 OAP59867.1 - 1.2 6.6 30.1 2.9 5.3 30.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) TcdB_N PF12918.7 OAP59867.1 - 1.2 9.5 6.8 13 6.1 0.3 3.4 3 0 0 3 3 3 0 TcdB toxin N-terminal helical domain RSS_P20 PF11757.8 OAP59867.1 - 1.5 9.4 6.2 0.58 10.6 1.0 2.6 1 1 0 2 2 2 0 Suppressor of RNA silencing P21-like N-terminal domain MCPsignal PF00015.21 OAP59867.1 - 2 8.2 5.1 11 5.7 0.7 3.0 3 1 1 4 4 4 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Fib_alpha PF08702.10 OAP59867.1 - 2.5 8.3 21.2 0.64 10.2 1.9 3.8 1 1 1 3 3 3 0 Fibrinogen alpha/beta chain family PspA_IM30 PF04012.12 OAP59867.1 - 3.3 7.2 33.4 0.028 14.0 4.6 3.8 3 1 1 4 4 4 0 PspA/IM30 family Sec34 PF04136.15 OAP59867.1 - 4.1 7.3 17.1 0.6 10.0 3.9 2.7 3 0 0 3 3 2 0 Sec34-like family Ribonuc_2-5A PF06479.12 OAP59867.1 - 4.4 7.5 6.2 1.1 9.5 0.7 2.4 3 0 0 3 3 2 0 Ribonuclease 2-5A DUF4407 PF14362.6 OAP59867.1 - 4.4 6.6 27.6 1.8e+04 -8.8 27.6 2.9 1 1 0 1 1 0 0 Domain of unknown function (DUF4407) CENP-H PF05837.12 OAP59867.1 - 5.3 7.5 25.4 9.4 6.7 10.4 4.3 2 1 0 3 3 3 0 Centromere protein H (CENP-H) Borrelia_REV PF03978.13 OAP59867.1 - 5.3 7.0 7.7 0.44 10.5 0.3 2.5 3 0 0 3 3 3 0 Borrelia burgdorferi REV protein Laminin_II PF06009.12 OAP59867.1 - 5.7 7.0 21.4 0.52 10.3 1.8 3.2 2 2 0 3 3 3 0 Laminin Domain II HMMR_N PF15905.5 OAP59867.1 - 6.5 6.1 35.5 0.56 9.6 9.6 3.2 2 1 1 3 3 3 0 Hyaluronan mediated motility receptor N-terminal FlaC_arch PF05377.11 OAP59867.1 - 8 6.9 22.4 0.55 10.7 0.3 4.6 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) Sec8_exocyst PF04048.14 OAP59867.1 - 9.4 6.1 11.8 2.2 8.2 0.6 3.6 3 1 1 4 4 4 0 Sec8 exocyst complex component specific domain DUF948 PF06103.11 OAP59867.1 - 9.5 6.6 9.3 0.32 11.3 0.9 2.8 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) YscO PF07321.12 OAP59867.1 - 9.5 6.2 39.4 0.19 11.7 4.5 3.9 2 1 2 4 4 4 0 Type III secretion protein YscO ATP-synt_DE PF00401.20 OAP59868.1 - 0.016 15.4 0.7 0.032 14.5 0.7 1.4 1 0 0 1 1 1 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain AA_permease PF00324.21 OAP59869.1 - 1.5e-140 469.0 37.3 1.7e-140 468.8 37.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAP59869.1 - 4.2e-37 128.0 39.6 5.4e-37 127.6 39.6 1.0 1 0 0 1 1 1 1 Amino acid permease DUF4781 PF16013.5 OAP59869.1 - 0.052 12.4 0.1 0.088 11.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4781) FMN_dh PF01070.18 OAP59870.1 - 1.4e-119 399.2 0.0 1.7e-119 399.0 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 OAP59870.1 - 1.5e-23 82.7 0.0 3.5e-23 81.5 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 OAP59870.1 - 2.2e-09 36.9 0.0 4.2e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 OAP59870.1 - 0.00016 20.8 0.4 0.00029 19.9 0.0 1.5 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 OAP59870.1 - 0.0016 17.9 0.1 0.0022 17.4 0.1 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.21 OAP59870.1 - 0.049 13.1 0.8 0.62 9.5 0.1 2.2 1 1 0 2 2 2 0 Histidine biosynthesis protein ThiG PF05690.14 OAP59870.1 - 0.082 12.2 0.1 8.1 5.7 0.0 2.3 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG DUF676 PF05057.14 OAP59871.1 - 4.3e-40 137.5 0.1 1e-25 90.5 0.0 3.7 4 0 0 4 4 4 3 Putative serine esterase (DUF676) DUF3597 PF12200.8 OAP59871.1 - 0.19 12.3 0.8 0.95 10.0 0.8 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3597) MFS_1 PF07690.16 OAP59872.1 - 4.6e-18 65.3 27.2 7.6e-18 64.5 27.2 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 OAP59872.1 - 5.1e-11 42.5 6.9 5.1e-11 42.5 6.9 2.9 4 0 0 4 4 4 1 Ion channel regulatory protein UNC-93 MFS_1_like PF12832.7 OAP59872.1 - 0.00068 18.6 8.4 0.00068 18.6 8.4 2.6 1 1 2 3 3 3 1 MFS_1 like family PUCC PF03209.15 OAP59872.1 - 0.0017 17.5 2.9 0.041 12.9 1.3 2.9 2 1 1 3 3 3 1 PUCC protein SPC12 PF06645.13 OAP59872.1 - 1.7 8.8 9.8 1.1 9.4 0.9 4.0 3 1 0 3 3 3 0 Microsomal signal peptidase 12 kDa subunit (SPC12) Amidohydro_1 PF01979.20 OAP59873.1 - 2.9e-15 56.4 0.1 4.2e-14 52.6 0.1 2.1 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 OAP59873.1 - 2.9e-09 36.9 0.1 6e-06 26.0 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Peptidase_S9 PF00326.21 OAP59874.1 - 1.3e-51 175.1 0.0 2.2e-51 174.4 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family PD40 PF07676.12 OAP59874.1 - 0.0011 18.8 0.0 0.12 12.3 0.0 3.1 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat AXE1 PF05448.12 OAP59874.1 - 0.0039 15.9 0.2 0.086 11.5 0.2 2.2 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) YqeY PF09424.10 OAP59875.1 - 3.6e-14 53.1 5.3 4.1e-14 52.9 5.3 1.1 1 0 0 1 1 1 1 Yqey-like protein GAT PF03127.14 OAP59875.1 - 0.12 12.7 0.0 0.43 10.9 0.0 1.9 1 1 1 2 2 2 0 GAT domain Nucleoporin_N PF08801.11 OAP59876.1 - 5.2e-95 318.7 0.0 7.1e-95 318.3 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 OAP59876.1 - 1.5e-56 192.4 5.4 7.9e-56 190.0 5.3 1.9 1 1 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal DUF2781 PF10914.8 OAP59877.1 - 2.4e-35 122.1 13.1 2.9e-35 121.8 13.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) DUF4728 PF15860.5 OAP59877.1 - 0.048 14.3 1.6 0.048 14.3 1.6 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4728) LacAB_rpiB PF02502.18 OAP59878.1 - 6.3e-45 152.6 0.4 7.1e-45 152.4 0.4 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase Gly_rich_SFCGS PF14272.6 OAP59878.1 - 0.0093 16.0 0.0 0.014 15.4 0.0 1.4 1 1 0 1 1 1 1 Glycine-rich SFCGS DUF2620 PF10941.8 OAP59878.1 - 0.067 13.3 0.8 0.13 12.4 0.7 1.5 1 1 0 1 1 1 0 Protein of unknown function DUF2620 BTB PF00651.31 OAP59879.1 - 4.9e-17 62.1 0.0 8e-17 61.5 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain zf-HIT PF04438.16 OAP59879.1 - 0.0021 17.9 2.9 0.0037 17.1 2.9 1.3 1 0 0 1 1 1 1 HIT zinc finger HypA PF01155.19 OAP59879.1 - 0.028 14.4 0.1 0.049 13.7 0.1 1.5 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn_Tnp_IS1595 PF12760.7 OAP59879.1 - 0.14 12.1 5.5 0.36 10.8 5.5 1.7 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Zn-ribbon_8 PF09723.10 OAP59879.1 - 0.29 11.3 3.6 0.61 10.3 3.6 1.5 1 0 0 1 1 1 0 Zinc ribbon domain Fungal_lectin PF07938.12 OAP59880.1 - 1.1e-07 31.5 0.3 6.2e-06 25.8 0.0 2.2 1 1 1 2 2 2 2 Fungal fucose-specific lectin TIM PF00121.18 OAP59881.1 - 3.4e-35 121.6 0.0 1.3e-34 119.7 0.0 1.8 2 0 0 2 2 2 1 Triosephosphate isomerase SMC_N PF02463.19 OAP59882.1 - 8.6e-71 237.9 0.0 2.4e-70 236.4 0.0 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 OAP59882.1 - 2.1e-22 79.6 0.8 1.9e-20 73.4 0.1 3.2 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 OAP59882.1 - 6.7e-10 39.3 4.8 0.00065 19.6 0.0 4.0 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran PF00005.27 OAP59882.1 - 0.00063 20.3 0.0 0.00063 20.3 0.0 6.6 5 2 0 5 5 5 2 ABC transporter AAA_29 PF13555.6 OAP59882.1 - 0.0012 18.6 0.1 0.0028 17.4 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain GAS PF13851.6 OAP59882.1 - 0.0012 18.2 7.6 0.0012 18.2 7.6 7.3 2 2 3 6 6 6 2 Growth-arrest specific micro-tubule binding HSBP1 PF06825.12 OAP59882.1 - 0.34 10.8 9.0 1.5 8.8 0.1 4.9 4 0 0 4 4 4 0 Heat shock factor binding protein 1 AAA_23 PF13476.6 OAP59882.1 - 4.9 7.6 105.1 1.7 9.1 42.3 6.5 2 2 0 2 2 2 0 AAA domain MRP-L47 PF06984.13 OAP59883.1 - 7.3e-22 77.3 0.2 1.1e-21 76.7 0.2 1.3 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Fungal_trans PF04082.18 OAP59884.1 - 1.4e-11 43.9 2.6 2.1e-11 43.4 2.6 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain U6-snRNA_bdg PF10596.9 OAP59884.1 - 0.042 13.8 0.0 0.077 12.9 0.0 1.3 1 0 0 1 1 1 0 U6-snRNA interacting domain of PrP8 NmrA PF05368.13 OAP59885.1 - 9.1e-05 22.1 0.0 0.0012 18.4 0.0 2.1 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.6 OAP59885.1 - 0.00025 21.0 0.0 0.00053 19.9 0.0 1.5 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 OAP59885.1 - 0.0044 16.5 0.0 0.042 13.3 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.6 OAP59886.1 - 1.4e-60 204.8 0.4 1.6e-60 204.6 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP59886.1 - 1e-44 152.4 0.4 1.3e-44 152.0 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAP59886.1 - 9.9e-08 32.1 0.1 1.3e-07 31.7 0.1 1.1 1 0 0 1 1 1 1 KR domain IMPDH PF00478.25 OAP59886.1 - 0.041 12.9 0.0 0.05 12.6 0.0 1.3 1 1 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain YjeF_N PF03853.15 OAP59886.1 - 0.055 13.4 0.2 0.086 12.7 0.2 1.3 1 0 0 1 1 1 0 YjeF-related protein N-terminus AdoHcyase_NAD PF00670.21 OAP59886.1 - 0.12 12.5 1.3 0.27 11.3 1.3 1.5 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain DUF1776 PF08643.10 OAP59886.1 - 0.18 11.2 0.0 0.25 10.7 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) TPP_enzyme_N PF02776.18 OAP59887.1 - 2.1e-31 108.9 0.1 3.8e-31 108.0 0.1 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 OAP59887.1 - 7.4e-17 61.4 0.0 3e-16 59.4 0.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 OAP59887.1 - 5.4e-15 55.5 0.2 1.1e-14 54.5 0.2 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain GDI PF00996.18 OAP59888.1 - 2.2e-190 632.8 0.0 2.5e-190 632.6 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.6 OAP59888.1 - 0.0071 16.6 0.0 0.019 15.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Fungal_trans_2 PF11951.8 OAP59890.1 - 1.6e-17 63.4 0.8 1.6e-17 63.4 0.8 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Methyltransf_8 PF05148.15 OAP59891.1 - 2.5e-55 187.7 0.0 7.3e-52 176.4 0.0 2.9 3 1 0 3 3 3 2 Hypothetical methyltransferase Methyltransf_11 PF08241.12 OAP59891.1 - 0.0012 19.5 0.0 0.0039 17.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAP59891.1 - 0.021 15.5 0.1 0.15 12.8 0.1 2.3 1 1 0 1 1 1 0 Methyltransferase domain DUF1174 PF06671.11 OAP59891.1 - 0.032 13.9 2.1 0.032 13.9 2.1 1.9 2 0 0 2 2 2 0 Repeat of unknown function (DUF1174) GCP_N_terminal PF17681.1 OAP59894.1 - 4.8e-64 216.9 0.0 7.2e-64 216.3 0.0 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 OAP59894.1 - 1.2e-52 179.3 1.8 1.9e-52 178.7 1.8 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal Polysacc_deac_1 PF01522.21 OAP59896.1 - 3.4e-13 49.6 0.0 5.1e-13 49.0 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase Oxidored_FMN PF00724.20 OAP59897.1 - 3.5e-72 243.6 0.0 4.9e-72 243.1 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Polysacc_deac_1 PF01522.21 OAP59898.1 - 2.2e-09 37.2 0.0 4.2e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Amidase PF01425.21 OAP59899.1 - 9.4e-81 272.1 0.0 1.2e-80 271.7 0.0 1.1 1 0 0 1 1 1 1 Amidase Aa_trans PF01490.18 OAP59900.1 - 3.9e-23 81.8 29.8 5e-23 81.5 29.8 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.6 OAP59900.1 - 0.83 8.4 42.5 2.5e+02 0.2 42.5 2.3 1 1 0 1 1 1 0 Amino acid permease Candida_ALS PF05792.13 OAP59900.1 - 2.5 8.8 5.9 6.7 7.4 5.9 1.8 1 0 0 1 1 1 0 Candida agglutinin-like (ALS) SLATT_1 PF18181.1 OAP59900.1 - 9.6 6.2 17.6 6.2 6.8 1.7 3.8 4 0 0 4 4 4 0 SMODS and SLOG-associating 2TM effector domain 1 Proteasome PF00227.26 OAP59901.1 - 1.5e-55 187.7 0.0 1.9e-55 187.3 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 OAP59901.1 - 1.6e-12 46.8 0.2 3.6e-12 45.7 0.0 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature TauD PF02668.16 OAP59902.1 - 2e-56 191.7 0.1 2.7e-56 191.3 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family ATG_C PF09333.11 OAP59902.1 - 0.077 13.3 0.1 0.25 11.7 0.0 1.8 2 0 0 2 2 2 0 Autophagy-related protein C terminal domain Peptidase_M3 PF01432.20 OAP59905.1 - 1.5e-160 535.5 0.0 3.5e-160 534.2 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M3 MSP7_C PF12948.7 OAP59905.1 - 0.041 14.6 0.1 20 5.8 0.0 3.0 3 0 0 3 3 3 0 MSP7-like protein C-terminal domain AF0941-like PF14591.6 OAP59905.1 - 0.2 12.2 0.1 0.2 12.2 0.1 2.2 3 0 0 3 3 3 0 AF0941-like Arf PF00025.21 OAP59906.1 - 1.8e-72 242.5 0.0 2e-72 242.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 OAP59906.1 - 2.4e-13 50.3 0.0 3.5e-13 49.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 OAP59906.1 - 5.1e-12 45.6 0.2 6.1e-08 32.2 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 OAP59906.1 - 8.5e-11 41.6 0.0 1.1e-10 41.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 OAP59906.1 - 3e-09 36.7 0.0 3.4e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 OAP59906.1 - 8.7e-08 31.8 0.0 1.2e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OAP59906.1 - 1.3e-06 28.5 0.0 2.6e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase MeaB PF03308.16 OAP59906.1 - 0.021 13.8 0.4 0.086 11.8 0.1 2.1 2 1 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB FeoB_N PF02421.18 OAP59906.1 - 0.027 14.0 0.3 0.12 11.9 0.2 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B GTP_EFTU PF00009.27 OAP59906.1 - 0.061 12.9 0.1 3.9 7.0 0.0 2.1 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Actin PF00022.19 OAP59907.1 - 7e-30 103.9 0.0 7.6e-19 67.6 0.0 2.6 2 1 0 2 2 2 2 Actin MreB_Mbl PF06723.13 OAP59907.1 - 1.5e-06 27.3 0.0 0.00098 18.0 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein Actin_micro PF17003.5 OAP59907.1 - 5.1e-05 22.6 0.2 0.00011 21.6 0.0 1.5 2 0 0 2 2 2 1 Putative actin-like family FtsA PF14450.6 OAP59907.1 - 9.9e-05 22.7 0.0 0.00032 21.1 0.0 2.0 2 1 0 2 2 2 1 Cell division protein FtsA PilM_2 PF11104.8 OAP59907.1 - 0.00028 20.0 0.2 0.094 11.7 0.0 2.2 2 0 0 2 2 2 2 Type IV pilus assembly protein PilM; Abhydrolase_1 PF00561.20 OAP59908.1 - 7.1e-18 65.2 0.0 1.3e-16 61.0 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAP59908.1 - 2.2e-13 51.3 0.0 3.7e-13 50.6 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAP59908.1 - 7e-11 41.8 0.0 5.8e-10 38.8 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 OAP59908.1 - 4.1e-05 22.4 0.0 6.3e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Ndr family Helicase_C PF00271.31 OAP59909.1 - 2.1e-14 53.8 0.0 5e-14 52.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HA2 PF04408.23 OAP59909.1 - 2.1e-11 44.1 0.0 7.9e-11 42.2 0.0 2.0 1 0 0 1 1 1 1 Helicase associated domain (HA2) DEAD PF00270.29 OAP59909.1 - 1.1e-10 41.6 0.1 6.9e-10 39.0 0.1 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_19 PF13245.6 OAP59909.1 - 0.00029 21.2 0.0 0.00077 19.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 OAP59909.1 - 0.015 15.0 0.0 0.033 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 OAP59909.1 - 0.054 12.9 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein adh_short PF00106.25 OAP59910.1 - 8.4e-37 126.5 0.2 1.1e-36 126.2 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP59910.1 - 2.3e-26 92.8 0.0 2.8e-26 92.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP59910.1 - 0.0017 18.3 0.0 0.0025 17.7 0.0 1.3 1 0 0 1 1 1 1 KR domain ADH_zinc_N PF00107.26 OAP59910.1 - 0.098 12.6 0.2 1.4 8.9 0.0 2.3 2 0 0 2 2 2 0 Zinc-binding dehydrogenase NmrA PF05368.13 OAP59910.1 - 0.14 11.7 0.0 0.28 10.7 0.0 1.5 1 0 0 1 1 1 0 NmrA-like family RNA_pol_inhib PF16857.5 OAP59911.1 - 0.053 13.3 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase inhibitor Metallophos PF00149.28 OAP59912.1 - 1.4e-09 38.7 0.8 1.4e-09 38.7 0.8 2.1 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase 5_nucleotid_C PF02872.18 OAP59912.1 - 0.044 14.0 0.0 0.095 12.9 0.0 1.5 1 0 0 1 1 1 0 5'-nucleotidase, C-terminal domain Transket_pyr PF02779.24 OAP59913.1 - 4.9e-49 166.4 0.0 7.7e-49 165.8 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 OAP59913.1 - 1.5e-34 118.6 0.0 3.5e-34 117.4 0.0 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain DUF1691 PF07950.11 OAP59915.1 - 1.7e-21 76.9 1.1 6.6e-15 55.7 0.3 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1691) Cytochrom_B562 PF07361.11 OAP59916.1 - 0.0046 17.6 7.9 0.1 13.3 3.8 3.3 3 0 0 3 3 3 1 Cytochrome b562 Cep57_CLD_2 PF14197.6 OAP59916.1 - 0.0063 16.6 0.8 0.0063 16.6 0.8 4.3 3 1 0 3 3 3 1 Centrosome localisation domain of PPC89 BRE1 PF08647.11 OAP59916.1 - 0.0087 16.1 1.0 0.0087 16.1 1.0 5.3 3 2 2 5 5 5 1 BRE1 E3 ubiquitin ligase APG6_N PF17675.1 OAP59916.1 - 0.12 12.9 41.0 0.24 11.9 5.3 4.9 3 2 1 5 5 5 0 Apg6 coiled-coil region AKNA PF12443.8 OAP59916.1 - 0.15 12.7 11.0 0.038 14.6 2.1 4.2 3 2 1 4 4 4 0 AT-hook-containing transcription factor PEP-utilisers_N PF05524.13 OAP59916.1 - 0.18 12.0 6.4 6.7 6.9 3.4 3.3 3 0 0 3 3 3 0 PEP-utilising enzyme, N-terminal Shugoshin_N PF07558.11 OAP59916.1 - 0.37 10.7 4.0 1.4 8.9 0.5 3.3 3 1 1 4 4 4 0 Shugoshin N-terminal coiled-coil region Spc7 PF08317.11 OAP59916.1 - 2.1 7.1 37.7 0.2 10.5 1.3 4.1 2 2 2 4 4 4 0 Spc7 kinetochore protein zf-C2H2_jaz PF12171.8 OAP59917.1 - 3.1e-06 27.3 3.3 5.3e-06 26.6 3.3 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OAP59917.1 - 0.011 16.1 0.8 0.02 15.3 0.8 1.5 1 0 0 1 1 1 0 Zinc-finger of C2H2 type TRM PF02005.16 OAP59919.1 - 4.9e-107 358.4 0.0 5.3e-94 315.5 0.0 2.1 1 1 1 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.16 OAP59919.1 - 4.2e-07 29.9 0.0 9.3e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 Met-10+ like-protein Gag_p12 PF01141.18 OAP59920.1 - 0.15 12.5 1.5 1.7 9.0 0.1 2.6 2 0 0 2 2 2 0 Gag polyprotein, inner coat protein p12 Fe-S_biosyn PF01521.20 OAP59921.1 - 1.8e-10 41.0 0.1 1.3e-09 38.3 0.1 2.3 1 1 0 1 1 1 1 Iron-sulphur cluster biosynthesis Aminotran_5 PF00266.19 OAP59922.1 - 7.8e-07 28.4 0.0 6.4e-06 25.4 0.0 1.9 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 OAP59922.1 - 0.21 10.8 0.0 0.35 10.1 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family F-box-like PF12937.7 OAP59923.1 - 0.0046 16.8 0.6 0.014 15.2 0.0 2.1 2 0 0 2 2 2 1 F-box-like MCM_bind PF09739.9 OAP59923.1 - 0.093 11.2 0.0 0.13 10.6 0.0 1.2 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Rad9 PF04139.13 OAP59924.1 - 3.4e-53 180.6 0.0 4.8e-53 180.2 0.0 1.1 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.16 OAP59924.1 - 1.7e-05 24.0 0.0 6.5e-05 22.1 0.0 1.9 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 RCC1 PF00415.18 OAP59925.1 - 5.3e-22 78.2 16.2 6.1e-07 30.0 0.6 7.9 8 1 0 8 8 8 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OAP59925.1 - 8.9e-17 60.4 18.8 0.00024 20.8 0.0 6.9 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat Glyco_hydro_3_C PF01915.22 OAP59926.1 - 7.2e-64 215.5 0.0 1.3e-63 214.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 OAP59926.1 - 5.7e-48 163.9 0.0 9e-48 163.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 OAP59926.1 - 5.7e-24 84.0 1.2 1.2e-23 82.9 1.2 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 OAP59926.1 - 1.2e-10 41.4 0.0 2.3e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 PA14 domain Nucleo_P87 PF07267.11 OAP59927.1 - 0.31 9.8 5.5 0.38 9.6 5.5 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 HRI1 PF16815.5 OAP59928.1 - 3.8e-59 200.2 0.1 4.5e-59 199.9 0.1 1.1 1 0 0 1 1 1 1 Protein HRI1 Bac_surface_Ag PF01103.23 OAP59929.1 - 3.1e-42 145.2 0.9 6.1e-42 144.3 0.9 1.5 1 0 0 1 1 1 1 Surface antigen Yip1 PF04893.17 OAP59929.1 - 0.00044 20.0 15.2 0.0025 17.6 15.2 2.0 1 1 0 1 1 1 1 Yip1 domain UQ_con PF00179.26 OAP59930.1 - 1.2e-18 67.1 0.0 1.7e-18 66.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF2631 PF10939.8 OAP59930.1 - 0.086 12.7 0.3 0.19 11.6 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2631) Prok-E2_B PF14461.6 OAP59930.1 - 0.13 11.9 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B Fungal_trans_2 PF11951.8 OAP59931.1 - 2.3e-06 26.7 0.3 0.0032 16.3 0.1 2.3 2 1 0 2 2 2 2 Fungal specific transcription factor domain Cyto_heme_lyase PF01265.17 OAP59932.1 - 7.2e-118 393.4 1.8 8.4e-118 393.2 1.8 1.0 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase Paf1 PF03985.13 OAP59933.1 - 2.2e-48 165.3 0.1 3.2e-48 164.8 0.1 1.2 1 0 0 1 1 1 1 Paf1 TINF2_N PF14973.6 OAP59933.1 - 0.15 12.4 0.1 0.29 11.5 0.1 1.4 1 0 0 1 1 1 0 TERF1-interacting nuclear factor 2 N-terminus Paf67 PF10255.9 OAP59934.1 - 4.1e-153 510.2 0.0 4.8e-153 509.9 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TRAPPC-Trs85 PF12739.7 OAP59934.1 - 0.038 13.0 0.1 0.054 12.5 0.1 1.3 1 0 0 1 1 1 0 ER-Golgi trafficking TRAPP I complex 85 kDa subunit TPR_2 PF07719.17 OAP59934.1 - 0.039 14.1 0.0 0.25 11.5 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat CN_hydrolase PF00795.22 OAP59935.1 - 1.6e-26 93.3 0.0 2.4e-26 92.7 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase LysR_substrate PF03466.20 OAP59935.1 - 0.047 13.0 0.0 5.2 6.4 0.0 2.2 2 0 0 2 2 2 0 LysR substrate binding domain zf-MYND PF01753.18 OAP59937.1 - 8.3e-12 45.0 10.5 1.4e-11 44.2 10.5 1.4 1 0 0 1 1 1 1 MYND finger Lyase_8 PF02278.18 OAP59937.1 - 0.16 11.4 0.0 0.23 10.9 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide lyase family 8, super-sandwich domain zf-C6H2 PF15801.5 OAP59937.1 - 2.1 8.7 11.8 9.7 6.6 11.8 2.1 1 1 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding DUF805 PF05656.14 OAP59938.1 - 0.009 16.4 3.0 0.053 13.9 0.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF805) DuoxA PF10204.9 OAP59938.1 - 0.19 10.7 11.9 0.16 10.9 2.7 2.1 2 0 0 2 2 2 0 Dual oxidase maturation factor DUF3054 PF11255.8 OAP59938.1 - 0.4 11.2 5.6 0.87 10.1 5.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3054) Rhodanese PF00581.20 OAP59939.1 - 2.2e-07 31.4 0.2 5.3e-07 30.1 0.2 1.6 1 1 0 1 1 1 1 Rhodanese-like domain CSD PF00313.22 OAP59939.1 - 0.15 12.0 0.0 0.26 11.2 0.0 1.3 1 0 0 1 1 1 0 'Cold-shock' DNA-binding domain 3Beta_HSD PF01073.19 OAP59939.1 - 0.16 11.0 0.0 0.21 10.6 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family MscS_TM PF12794.7 OAP59939.1 - 1.7 7.5 5.0 2.2 7.1 5.0 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Ribosomal_S21 PF01165.20 OAP59940.1 - 4.8e-08 32.6 1.2 4.8e-08 32.6 1.2 1.9 2 0 0 2 2 2 1 Ribosomal protein S21 zf-C3HC4_3 PF13920.6 OAP59941.1 - 0.00072 19.4 3.2 0.0013 18.6 3.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAP59941.1 - 0.0016 18.3 1.8 0.0035 17.2 1.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prominin PF05478.11 OAP59941.1 - 0.017 13.1 1.1 0.025 12.6 1.1 1.1 1 0 0 1 1 1 0 Prominin zf-RING_5 PF14634.6 OAP59941.1 - 0.018 15.0 5.6 0.035 14.1 5.6 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 OAP59941.1 - 0.019 15.0 1.2 0.048 13.7 1.2 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OAP59941.1 - 0.046 13.6 2.9 0.093 12.6 2.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) UPF0240 PF06784.11 OAP59941.1 - 0.071 13.2 0.9 0.75 9.8 1.1 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0240) zf-RING_6 PF14835.6 OAP59941.1 - 0.08 12.8 2.2 0.16 11.8 2.2 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein IL17R_fnIII_D2 PF16578.5 OAP59941.1 - 0.1 13.1 0.7 0.25 11.9 0.7 1.6 1 0 0 1 1 1 0 Interleukin 17 receptor D DASH_Dad2 PF08654.10 OAP59941.1 - 0.11 12.9 3.4 0.24 11.8 1.0 2.5 3 0 0 3 3 3 0 DASH complex subunit Dad2 zf-C3HC4_4 PF15227.6 OAP59941.1 - 0.12 12.6 0.8 0.28 11.4 0.8 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 OAP59941.1 - 0.16 11.8 4.6 0.32 10.9 4.6 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 DIL PF01843.19 OAP59941.1 - 0.22 11.8 1.2 0.52 10.6 1.2 1.6 1 0 0 1 1 1 0 DIL domain Spc24 PF08286.11 OAP59941.1 - 0.25 11.6 2.0 1.3 9.3 2.5 1.9 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 SKA2 PF16740.5 OAP59941.1 - 0.33 10.8 5.0 0.34 10.7 3.0 2.1 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 Vps51 PF08700.11 OAP59941.1 - 0.91 9.6 4.5 5.7 7.1 4.5 2.2 1 1 0 1 1 1 0 Vps51/Vps67 Med9 PF07544.13 OAP59941.1 - 2.6 8.2 5.2 2.5 8.3 1.4 2.7 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 FAD_binding_7 PF03441.14 OAP59942.1 - 2.2e-54 184.0 1.3 2.2e-54 184.0 1.3 1.8 2 0 0 2 2 2 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 OAP59942.1 - 9.6e-42 142.8 0.3 5.2e-41 140.4 0.0 2.1 2 0 0 2 2 2 1 DNA photolyase Fungal_trans PF04082.18 OAP59943.1 - 3.3e-19 69.0 0.2 6.3e-19 68.0 0.2 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.6 OAP59943.1 - 2.1e-07 31.1 6.9 3.3e-06 27.3 0.9 2.8 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 OAP59943.1 - 0.00054 20.6 12.6 0.067 14.1 3.8 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.12 OAP59943.1 - 0.0086 16.4 4.1 0.017 15.4 4.1 1.4 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.26 OAP59943.1 - 0.0092 16.4 12.3 0.045 14.2 5.3 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 OAP59943.1 - 0.43 10.9 3.1 6.9 7.1 0.1 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Sugar_tr PF00083.24 OAP59944.1 - 1.6e-75 254.7 18.6 1.9e-75 254.5 18.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP59944.1 - 1.5e-23 83.3 17.7 1.5e-23 83.3 17.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 OAP59944.1 - 0.0025 16.7 4.9 0.0054 15.6 4.9 1.5 1 0 0 1 1 1 1 MFS_1 like family ORC4_C PF14629.6 OAP59945.1 - 2.7e-44 151.2 0.0 4.1e-44 150.6 0.0 1.3 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.6 OAP59945.1 - 1.2e-14 55.1 0.2 3.3e-14 53.6 0.2 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OAP59945.1 - 2.1e-06 28.1 0.0 5.9e-06 26.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 OAP59945.1 - 2.8e-05 24.5 0.0 0.00013 22.4 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 OAP59945.1 - 0.0003 20.7 0.0 0.0016 18.4 0.0 2.1 1 1 0 1 1 1 1 NACHT domain ATPase_2 PF01637.18 OAP59945.1 - 0.00089 19.2 0.0 0.0016 18.4 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea DUF815 PF05673.13 OAP59945.1 - 0.0017 17.6 0.0 0.0027 16.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Mg_chelatase PF01078.21 OAP59945.1 - 0.034 13.5 0.0 0.24 10.8 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 OAP59945.1 - 0.05 13.6 0.0 1.1 9.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 OAP59945.1 - 0.051 13.1 0.0 0.094 12.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_19 PF13245.6 OAP59945.1 - 0.059 13.7 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain TPR_12 PF13424.6 OAP59947.1 - 6.1e-14 52.1 3.7 3.1e-08 33.8 0.2 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat Clr5 PF14420.6 OAP59947.1 - 3.9e-07 30.2 2.6 9.7e-07 28.9 2.6 1.7 1 0 0 1 1 1 1 Clr5 domain TPR_10 PF13374.6 OAP59947.1 - 4.4e-05 23.2 2.7 1.8 8.6 0.7 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 OAP59947.1 - 0.0047 16.9 5.3 0.18 12.0 0.2 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 OAP59947.1 - 0.0061 16.7 0.5 0.17 12.2 0.1 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 OAP59947.1 - 0.0079 16.2 2.1 0.35 11.0 0.4 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 OAP59947.1 - 0.056 14.0 0.4 10 6.7 0.1 2.9 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 OAP59947.1 - 0.062 14.1 7.5 1.5 9.8 0.4 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat SPA PF08616.10 OAP59947.1 - 0.1 12.5 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Stabilization of polarity axis TPR_4 PF07721.14 OAP59947.1 - 0.13 12.9 10.2 2.7 8.9 0.1 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat MFS_1 PF07690.16 OAP59948.1 - 4.6e-48 163.9 12.2 1.6e-42 145.7 6.8 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 OAP59948.1 - 2.7e-07 29.3 0.1 0.00022 19.6 0.1 2.4 2 0 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family MFS_4 PF06779.14 OAP59948.1 - 0.0044 16.4 4.2 0.0044 16.4 4.2 2.4 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB MFS_1_like PF12832.7 OAP59948.1 - 0.037 12.9 9.6 0.19 10.6 2.6 3.5 3 1 1 4 4 4 0 MFS_1 like family PUCC PF03209.15 OAP59948.1 - 0.46 9.4 16.5 0.077 12.0 5.8 3.1 3 2 0 3 3 3 0 PUCC protein DUF697 PF05128.12 OAP59948.1 - 0.47 10.1 3.6 0.71 9.6 2.6 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF697) Pterin_bind PF00809.22 OAP59949.1 - 4.7e-74 249.1 0.0 6.2e-74 248.7 0.0 1.2 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.20 OAP59949.1 - 4.1e-38 130.3 0.1 3.9e-37 127.2 0.0 2.4 3 0 0 3 3 3 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) NMO PF03060.15 OAP59950.1 - 6.6e-56 190.1 0.6 9.3e-56 189.6 0.6 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 OAP59950.1 - 1.4e-11 44.0 0.4 2.4e-11 43.3 0.4 1.3 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 OAP59950.1 - 7.1e-06 25.3 0.8 1.3e-05 24.5 0.8 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase DHO_dh PF01180.21 OAP59950.1 - 0.0008 18.7 0.1 0.0015 17.8 0.1 1.5 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase Glu_synthase PF01645.17 OAP59950.1 - 0.0084 15.3 0.3 0.017 14.3 0.3 1.5 1 0 0 1 1 1 1 Conserved region in glutamate synthase HSP70 PF00012.20 OAP59951.1 - 3.2e-15 55.4 0.1 5.8e-15 54.5 0.0 1.3 2 0 0 2 2 2 1 Hsp70 protein GAS PF13851.6 OAP59952.1 - 0.00039 19.8 3.1 0.00065 19.1 3.1 1.2 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Golgin_A5 PF09787.9 OAP59952.1 - 0.0034 16.9 3.4 0.0063 16.0 3.4 1.4 1 0 0 1 1 1 1 Golgin subfamily A member 5 HAP1_N PF04849.13 OAP59952.1 - 0.0079 15.4 5.4 0.015 14.5 5.0 1.6 1 1 0 1 1 1 1 HAP1 N-terminal conserved region Spc7 PF08317.11 OAP59952.1 - 0.013 14.4 2.4 0.021 13.7 2.4 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4404 PF14357.6 OAP59952.1 - 0.013 16.1 3.1 2.3 8.9 1.0 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4404) Filament PF00038.21 OAP59952.1 - 0.014 15.0 1.5 0.021 14.4 1.5 1.2 1 0 0 1 1 1 0 Intermediate filament protein CENP-F_leu_zip PF10473.9 OAP59952.1 - 0.028 14.5 6.7 0.081 12.9 6.7 1.7 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CorA PF01544.18 OAP59952.1 - 0.11 11.8 0.4 0.17 11.1 0.4 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein HIP1_clath_bdg PF16515.5 OAP59952.1 - 0.29 11.8 7.1 1.9 9.1 6.2 2.1 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 PRKG1_interact PF15898.5 OAP59952.1 - 0.8 10.6 6.5 4.7 8.2 6.5 2.0 1 1 0 1 1 1 0 cGMP-dependent protein kinase interacting domain Bap31_Bap29_C PF18035.1 OAP59952.1 - 2 8.5 4.6 12 5.9 0.8 2.4 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain DivIC PF04977.15 OAP59952.1 - 3.5 7.5 7.7 2.1 8.2 2.8 2.3 1 1 1 2 2 2 0 Septum formation initiator eIF3g PF12353.8 OAP59953.1 - 6.6e-41 139.6 3.9 1e-40 139.0 3.9 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 OAP59953.1 - 3.8e-17 61.9 0.0 7.4e-17 60.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH_7 PF18586.1 OAP59953.1 - 0.013 15.8 0.1 0.032 14.6 0.1 1.6 1 0 0 1 1 1 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 1 RRM_occluded PF16842.5 OAP59953.1 - 0.12 12.2 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 Occluded RNA-recognition motif NDT80_PhoG PF05224.12 OAP59955.1 - 8.8e-36 123.9 0.0 1.3e-35 123.3 0.0 1.3 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family GCV_T PF01571.21 OAP59956.1 - 9e-74 248.1 0.0 1.1e-73 247.8 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 OAP59956.1 - 5.4e-19 67.9 0.0 9.6e-19 67.1 0.0 1.4 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain CHD5 PF04420.14 OAP59957.1 - 5.6e-54 182.3 0.1 7e-54 182.0 0.1 1.1 1 0 0 1 1 1 1 CHD5-like protein YnfE PF17452.2 OAP59957.1 - 0.0068 16.7 0.0 0.011 16.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized YnfE-like Peptidase_S49_N PF08496.10 OAP59957.1 - 0.056 13.5 1.7 0.062 13.4 0.7 1.5 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Adaptin_N PF01602.20 OAP59958.1 - 2.5e-120 402.5 10.0 3.2e-120 402.2 10.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 OAP59958.1 - 2.8e-53 180.3 10.3 1e-52 178.5 0.6 3.2 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 OAP59958.1 - 2.8e-14 53.3 5.3 1e-08 35.4 0.2 4.7 4 1 1 5 5 5 3 HEAT repeats HEAT PF02985.22 OAP59958.1 - 6.7e-10 38.4 4.2 0.062 13.6 0.1 5.8 7 0 0 7 7 6 3 HEAT repeat Arm PF00514.23 OAP59958.1 - 0.0012 18.8 2.0 10 6.3 0.0 5.1 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 OAP59958.1 - 0.0013 19.1 7.5 12 6.5 0.1 6.0 6 1 1 7 7 7 2 HEAT-like repeat CLASP_N PF12348.8 OAP59958.1 - 0.0049 16.5 1.4 8.6 5.8 0.0 3.6 3 1 0 3 3 3 2 CLASP N terminal RasGEF_N_2 PF14663.6 OAP59958.1 - 0.037 14.4 2.6 1.7 9.1 0.0 3.8 5 0 0 5 5 5 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Atx10homo_assoc PF09759.9 OAP59958.1 - 0.041 13.9 0.0 30 4.7 0.0 4.0 4 0 0 4 4 4 0 Spinocerebellar ataxia type 10 protein domain FANCI_S2 PF14676.6 OAP59958.1 - 0.044 14.1 2.8 42 4.4 0.1 3.9 3 2 0 3 3 3 0 FANCI solenoid 2 V-ATPase_H_C PF11698.8 OAP59958.1 - 1.3 9.1 3.2 7.3 6.7 0.0 3.6 4 1 0 4 4 4 0 V-ATPase subunit H DUF1077 PF06417.12 OAP59959.1 - 2.1e-50 169.6 1.5 2.6e-50 169.3 1.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) DUF4271 PF14093.6 OAP59959.1 - 0.031 14.2 0.2 0.042 13.7 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4271) RPAP2_Rtr1 PF04181.13 OAP59960.1 - 6.6e-21 74.4 0.1 1.3e-20 73.5 0.1 1.5 1 0 0 1 1 1 1 Rtr1/RPAP2 family SH3_2 PF07653.17 OAP59961.1 - 2.1e-09 36.9 0.0 3.9e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 OAP59961.1 - 2.6e-09 36.6 0.1 7.4e-09 35.1 0.1 1.9 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 OAP59961.1 - 7.8e-08 32.1 0.1 2.1e-07 30.7 0.1 1.8 1 0 0 1 1 1 1 Variant SH3 domain CUE PF02845.16 OAP59962.1 - 1.8e-07 30.7 0.0 2.8e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 CUE domain G2BR PF18442.1 OAP59962.1 - 0.0049 16.5 13.1 0.0083 15.7 13.1 1.4 1 0 0 1 1 1 1 E3 gp78 Ube2g2-binding region (G2BR) DAG1 PF05454.11 OAP59962.1 - 0.011 15.2 4.3 0.021 14.2 4.3 1.4 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) Sld5 PF05916.11 OAP59963.1 - 7.4e-31 106.8 0.0 1.3e-30 106.1 0.0 1.4 1 0 0 1 1 1 1 GINS complex protein DIE2_ALG10 PF04922.12 OAP59964.1 - 1.1e-119 400.3 13.6 1.4e-119 400.0 13.6 1.1 1 0 0 1 1 1 1 DIE2/ALG10 family Defensin_big PF14862.6 OAP59964.1 - 0.062 13.6 0.2 0.27 11.6 0.2 2.1 1 0 0 1 1 1 0 Big defensin AA_permease_2 PF13520.6 OAP59965.1 - 4.2e-51 174.1 49.7 7.4e-49 166.7 43.3 2.0 2 0 0 2 2 2 2 Amino acid permease AA_permease PF00324.21 OAP59965.1 - 6.1e-23 81.1 35.8 6.1e-23 81.1 35.8 1.9 2 0 0 2 2 2 1 Amino acid permease DUF2235 PF09994.9 OAP59966.1 - 2.7e-38 132.0 0.0 8.3e-38 130.4 0.0 1.7 1 1 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) DUF3970 PF13113.6 OAP59968.1 - 0.0039 17.4 0.2 0.0075 16.5 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3970) Fis1_TPR_C PF14853.6 OAP59968.1 - 0.078 13.1 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat RRM_1 PF00076.22 OAP59969.1 - 1.9e-09 37.2 0.0 4.3e-09 36.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 OAP59969.1 - 2e-07 30.9 0.0 3.8e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 OAP59969.1 - 0.0035 17.2 0.0 0.0088 15.9 0.0 1.7 1 0 0 1 1 1 1 Occluded RNA-recognition motif RRM_3 PF08777.11 OAP59969.1 - 0.012 15.7 0.0 0.027 14.5 0.0 1.6 1 0 0 1 1 1 0 RNA binding motif Alkyl_sulf_dimr PF14863.6 OAP59973.1 - 3.8 8.0 6.1 0.72 10.3 2.4 1.6 2 0 0 2 2 2 0 Alkyl sulfatase dimerisation APH PF01636.23 OAP59974.1 - 2.3e-11 44.1 0.1 3e-11 43.7 0.1 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 OAP59974.1 - 0.00022 20.7 0.0 0.00043 19.7 0.0 1.5 2 0 0 2 2 2 1 Ecdysteroid kinase Choline_kinase PF01633.20 OAP59974.1 - 0.00069 19.3 0.0 0.0011 18.6 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF2458 PF10454.9 OAP59977.1 - 8.2e-54 181.8 0.7 1.8e-53 180.7 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2458) DUF5617 PF18493.1 OAP59977.1 - 0.097 12.8 0.5 0.19 11.8 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5617) GET2 PF08690.10 OAP59977.1 - 6 6.5 7.4 1.7 8.2 1.0 2.1 2 0 0 2 2 2 0 GET complex subunit GET2 COX14 PF14880.6 OAP59978.1 - 6.2e-12 45.2 0.1 1.7e-11 43.7 0.1 1.8 1 0 0 1 1 1 1 Cytochrome oxidase c assembly HDV_ag PF01517.18 OAP59978.1 - 0.015 15.1 2.0 0.032 14.0 2.0 1.6 1 0 0 1 1 1 0 Hepatitis delta virus delta antigen TraF PF13728.6 OAP59978.1 - 0.063 13.1 0.2 0.12 12.2 0.2 1.4 1 0 0 1 1 1 0 F plasmid transfer operon protein DAHP_synth_1 PF00793.20 OAP59980.1 - 1.3e-99 332.6 0.1 1.5e-99 332.3 0.1 1.0 1 0 0 1 1 1 1 DAHP synthetase I family FAT PF02259.23 OAP59981.1 - 4.8e-117 391.1 0.9 4.8e-117 391.1 0.9 2.1 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.27 OAP59981.1 - 5.5e-73 245.8 0.6 1.6e-72 244.3 0.2 2.0 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.8 OAP59981.1 - 3.3e-60 202.7 6.3 1.2e-57 194.3 0.1 5.5 5 1 0 6 6 5 1 Domain of unknown function (DUF3385) FRB_dom PF08771.11 OAP59981.1 - 6.6e-42 142.0 2.6 8.9e-41 138.3 0.0 3.6 3 0 0 3 3 3 1 FKBP12-rapamycin binding domain HEAT_2 PF13646.6 OAP59981.1 - 2e-19 69.8 12.4 7.2e-06 26.3 0.1 9.4 7 2 1 9 9 9 4 HEAT repeats FATC PF02260.20 OAP59981.1 - 2.4e-16 59.3 0.2 2e-15 56.3 0.2 2.6 2 0 0 2 2 2 1 FATC domain HEAT_EZ PF13513.6 OAP59981.1 - 1.2e-12 48.0 13.4 0.44 11.1 0.0 11.7 11 1 2 13 13 11 3 HEAT-like repeat HEAT PF02985.22 OAP59981.1 - 2.2e-11 43.0 22.2 2.3 8.7 0.0 11.8 13 0 0 13 13 12 2 HEAT repeat TPR_19 PF14559.6 OAP59981.1 - 0.00032 21.1 0.2 4.3 7.9 0.0 5.5 5 0 0 5 5 4 1 Tetratricopeptide repeat MMS19_C PF12460.8 OAP59981.1 - 0.003 16.7 6.1 0.076 12.1 0.1 4.6 4 1 0 4 4 4 1 RNAPII transcription regulator C-terminal TPR_14 PF13428.6 OAP59981.1 - 0.0057 17.4 2.7 16 6.6 0.1 5.1 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 OAP59981.1 - 0.061 13.0 0.1 0.22 11.2 0.1 2.0 1 0 0 1 1 1 0 TPR repeat CLASP_N PF12348.8 OAP59981.1 - 0.071 12.7 0.1 15 5.1 0.0 4.1 4 0 0 4 4 4 0 CLASP N terminal ANAPC3 PF12895.7 OAP59981.1 - 1.2 9.5 4.4 15 5.9 0.2 3.7 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 OAP59981.1 - 2.2 8.6 5.3 12 6.3 0.2 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat PAP_assoc PF03828.19 OAP59982.1 - 2e-10 40.7 0.0 4.1e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 OAP59982.1 - 7.1e-08 32.6 0.0 1.6e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Fungal_trans_2 PF11951.8 OAP59983.1 - 5.2e-08 32.1 0.0 7.2e-08 31.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP59983.1 - 2e-07 31.0 10.5 3.5e-07 30.2 10.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FlaC_arch PF05377.11 OAP59983.1 - 0.055 13.9 0.1 0.22 11.9 0.1 2.1 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) LAP1C PF05609.12 OAP59983.1 - 0.066 12.3 3.3 0.1 11.6 3.3 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) FAM220 PF15487.6 OAP59983.1 - 0.38 10.3 4.3 0.84 9.2 4.3 1.6 1 0 0 1 1 1 0 FAM220 family DUF4698 PF15769.5 OAP59983.1 - 0.78 8.7 5.2 0.27 10.2 2.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4698) NPR3 PF03666.13 OAP59983.1 - 1.3 7.7 5.8 0.17 10.7 1.4 1.6 1 1 1 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 zf-RING_11 PF17123.5 OAP59985.1 - 1.7e-05 24.5 0.2 3.2e-05 23.6 0.2 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 OAP59985.1 - 0.0003 21.1 0.6 0.00052 20.3 0.6 1.3 1 0 0 1 1 1 1 Ring finger domain RNA_pol_I_TF PF04090.12 OAP59986.1 - 1.3e-05 24.8 0.0 9.5e-05 22.0 0.0 2.0 1 1 0 1 1 1 1 RNA polymerase I specific initiation factor DUF3419 PF11899.8 OAP59987.1 - 1.7e-154 514.7 0.0 2.1e-154 514.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_25 PF13649.6 OAP59987.1 - 3.6e-10 40.4 0.0 1.7e-09 38.3 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAP59987.1 - 3.9e-10 39.8 0.0 6.3e-09 35.9 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAP59987.1 - 2.3e-09 37.9 0.0 4.8e-08 33.7 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAP59987.1 - 3e-09 37.4 0.0 1.9e-08 34.8 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAP59987.1 - 2.2e-08 34.0 0.0 5.9e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAP59987.1 - 2.6e-08 33.5 0.0 5.5e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 OAP59987.1 - 6.3e-07 29.4 0.0 1.1e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Rsm22 PF09243.10 OAP59987.1 - 0.021 14.1 0.0 0.035 13.4 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 ADP_ribosyl_GH PF03747.14 OAP59989.1 - 5.7e-70 236.3 0.0 6.6e-70 236.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase Yip1 PF04893.17 OAP59990.1 - 1.3e-14 54.3 10.0 2e-14 53.6 10.0 1.4 1 0 0 1 1 1 1 Yip1 domain Ran_BP1 PF00638.18 OAP59991.1 - 7.2e-16 58.6 0.0 9e-10 38.9 0.2 2.4 2 0 0 2 2 2 2 RanBP1 domain Zn_Tnp_IS91 PF14319.6 OAP59992.1 - 0.21 11.6 0.2 0.21 11.6 0.2 2.1 2 0 0 2 2 2 0 Transposase zinc-binding domain RWD PF05773.22 OAP59994.1 - 0.00044 20.5 0.0 0.0017 18.6 0.0 2.0 1 1 0 1 1 1 1 RWD domain Amidohydro_2 PF04909.14 OAP59995.1 - 1.4e-34 120.2 0.2 1.8e-34 119.9 0.2 1.1 1 0 0 1 1 1 1 Amidohydrolase Fungal_trans PF04082.18 OAP59996.1 - 5.8e-13 48.5 3.0 2.6e-12 46.3 3.0 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP59996.1 - 6.1e-10 39.1 9.0 1.3e-09 38.0 9.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_3 PF01494.19 OAP59997.1 - 4.1e-22 78.9 0.0 6.1e-22 78.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAP59997.1 - 1.2e-07 31.6 7.7 0.003 17.2 3.8 2.3 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAP59997.1 - 7.4e-07 28.7 1.9 0.0023 17.2 0.4 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAP59997.1 - 1.3e-05 25.3 1.5 3.9e-05 23.8 1.5 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 OAP59997.1 - 3.9e-05 23.2 1.2 5.3e-05 22.7 1.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 OAP59997.1 - 6.2e-05 22.2 0.5 9.3e-05 21.6 0.5 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 OAP59997.1 - 7.5e-05 22.0 2.7 7.5e-05 22.0 2.7 1.9 2 0 0 2 2 2 1 FAD binding domain Trp_halogenase PF04820.14 OAP59997.1 - 0.00011 21.2 6.2 0.003 16.5 0.9 2.1 1 1 1 2 2 2 2 Tryptophan halogenase HI0933_like PF03486.14 OAP59997.1 - 0.0012 17.6 3.5 0.0042 15.9 2.0 2.0 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 OAP59997.1 - 0.0014 19.1 1.7 0.11 13.1 0.9 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 OAP59997.1 - 0.031 13.3 0.0 0.055 12.5 0.0 1.4 2 0 0 2 2 2 0 Squalene epoxidase Pyr_redox_3 PF13738.6 OAP59997.1 - 0.13 11.5 1.8 0.23 10.7 1.8 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 OAP59997.1 - 0.16 11.8 0.2 0.28 11.1 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Amino_oxidase PF01593.24 OAP59997.1 - 0.22 10.8 2.4 0.89 8.8 0.1 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase GIDA PF01134.22 OAP59997.1 - 0.45 9.5 2.2 0.65 9.0 2.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 OAP59997.1 - 1.2 8.4 3.5 2 7.7 1.3 2.0 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Transp_cyt_pur PF02133.15 OAP59998.1 - 1.5e-20 73.4 32.9 2.2e-20 72.9 32.9 1.3 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Fungal_trans PF04082.18 OAP59999.1 - 7.8e-16 57.9 0.9 1.6e-15 56.8 0.9 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.18 OAP60001.1 - 2e-30 105.7 0.0 3.6e-30 104.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP60001.1 - 3.1e-08 33.6 7.3 5e-08 32.9 7.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AAA PF00004.29 OAP60002.1 - 1.9e-36 125.4 0.0 4.8e-36 124.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OAP60002.1 - 1.1e-08 34.7 0.0 2.2e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 OAP60002.1 - 1.9e-05 25.1 2.3 0.00069 20.0 0.0 3.0 2 1 1 3 3 2 1 AAA ATPase domain RuvB_N PF05496.12 OAP60002.1 - 2.5e-05 24.1 0.0 4.7e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 OAP60002.1 - 3.7e-05 23.8 0.0 0.00018 21.5 0.0 2.0 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 OAP60002.1 - 5.2e-05 23.3 0.2 0.00038 20.5 0.2 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 OAP60002.1 - 0.0004 20.9 0.0 0.0016 18.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 OAP60002.1 - 0.00053 20.2 0.0 0.0013 18.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 OAP60002.1 - 0.00055 20.2 0.1 0.0068 16.7 0.0 2.5 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.17 OAP60002.1 - 0.00068 19.4 0.0 0.0013 18.5 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.6 OAP60002.1 - 0.00071 19.2 0.2 0.024 14.2 0.1 2.4 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 OAP60002.1 - 0.00087 18.7 0.1 0.0017 17.8 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 OAP60002.1 - 0.0011 19.2 0.4 0.021 15.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 OAP60002.1 - 0.0021 18.4 0.0 0.007 16.7 0.0 1.9 2 1 0 2 2 1 1 RNA helicase NACHT PF05729.12 OAP60002.1 - 0.0032 17.4 0.1 0.015 15.2 0.0 2.2 2 0 0 2 2 2 1 NACHT domain AAA_2 PF07724.14 OAP60002.1 - 0.0036 17.4 0.0 0.011 15.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) TniB PF05621.11 OAP60002.1 - 0.0048 16.3 0.0 3.1 7.2 0.0 2.9 1 1 2 3 3 3 1 Bacterial TniB protein DUF815 PF05673.13 OAP60002.1 - 0.0077 15.4 0.0 0.016 14.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_24 PF13479.6 OAP60002.1 - 0.0097 15.6 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.6 OAP60002.1 - 0.011 15.8 0.1 0.032 14.3 0.0 1.8 2 0 0 2 2 1 0 Sigma-54 interaction domain Rad17 PF03215.15 OAP60002.1 - 0.016 15.1 0.1 0.071 13.0 0.1 1.9 1 1 1 2 2 2 0 Rad17 P-loop domain AAA_11 PF13086.6 OAP60002.1 - 0.02 14.7 0.0 0.043 13.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 OAP60002.1 - 0.023 14.6 0.1 0.3 11.0 0.0 2.2 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea Parvo_NS1 PF01057.17 OAP60002.1 - 0.025 13.6 0.0 0.047 12.8 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Guanylate_kin PF00625.21 OAP60002.1 - 0.028 14.1 0.1 0.41 10.3 0.0 2.8 4 0 0 4 4 4 0 Guanylate kinase Sigma54_activat PF00158.26 OAP60002.1 - 0.038 13.7 0.0 0.076 12.7 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain ABC_tran PF00005.27 OAP60002.1 - 0.052 14.1 0.3 0.17 12.4 0.0 2.0 2 0 0 2 2 1 0 ABC transporter AAA_7 PF12775.7 OAP60002.1 - 0.069 12.7 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Bac_DnaA PF00308.18 OAP60002.1 - 0.076 12.8 0.0 0.25 11.2 0.0 1.8 2 0 0 2 2 2 0 Bacterial dnaA protein TsaE PF02367.17 OAP60002.1 - 0.093 12.7 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Viral_helicase1 PF01443.18 OAP60002.1 - 0.11 12.3 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase TIP49 PF06068.13 OAP60002.1 - 0.11 11.7 0.1 0.27 10.4 0.0 1.6 2 0 0 2 2 2 0 TIP49 P-loop domain CPT PF07931.12 OAP60002.1 - 0.12 12.3 0.2 0.41 10.5 0.0 2.0 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Tna_leader PF08053.11 OAP60002.1 - 0.16 11.9 0.5 0.38 10.8 0.5 1.6 1 0 0 1 1 1 0 Tryptophanase operon leader peptide Csm1 PF12539.8 OAP60003.1 - 3.5e-30 104.5 0.4 6.8e-30 103.5 0.4 1.5 1 0 0 1 1 1 1 Chromosome segregation protein Csm1/Pcs1 CheZ PF04344.13 OAP60003.1 - 0.037 13.9 5.3 0.18 11.7 4.3 2.4 2 0 0 2 2 2 0 Chemotaxis phosphatase, CheZ TPR_MLP1_2 PF07926.12 OAP60003.1 - 0.038 14.1 9.8 0.15 12.1 9.8 2.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein NYD-SP28 PF14772.6 OAP60003.1 - 0.092 12.8 10.6 0.038 14.0 5.1 2.6 1 1 1 2 2 2 0 Sperm tail SAM_KSR1 PF13543.6 OAP60003.1 - 0.12 12.5 3.2 2.1 8.5 0.3 2.7 1 1 2 3 3 3 0 SAM like domain present in kinase suppressor RAS 1 GAS PF13851.6 OAP60003.1 - 0.18 11.2 9.9 0.58 9.5 8.5 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF948 PF06103.11 OAP60003.1 - 0.23 11.8 1.3 2 8.8 1.0 2.7 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) Lipoprotein_20 PF13942.6 OAP60003.1 - 0.3 11.0 6.5 0.53 10.2 4.6 2.0 1 1 1 2 2 2 0 YfhG lipoprotein Csm1_N PF18504.1 OAP60003.1 - 0.46 10.9 5.2 3.1 8.2 1.8 3.6 2 1 2 4 4 4 0 Csm1 N-terminal domain BAR_3 PF16746.5 OAP60003.1 - 0.73 9.5 5.8 0.26 10.9 1.5 2.3 3 0 0 3 3 3 0 BAR domain of APPL family Bap31_Bap29_C PF18035.1 OAP60003.1 - 2 8.5 7.5 29 4.8 0.0 3.1 2 1 1 3 3 3 0 Bap31/Bap29 cytoplasmic coiled-coil domain DUF2203 PF09969.9 OAP60003.1 - 2.2 9.0 9.6 0.99 10.1 5.1 2.7 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) TMF_DNA_bd PF12329.8 OAP60003.1 - 6.8 6.8 13.1 0.94 9.5 4.0 3.3 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding ADIP PF11559.8 OAP60003.1 - 8.7 6.4 18.4 0.12 12.5 8.2 2.8 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding SOUL PF04832.12 OAP60004.1 - 0.0086 16.3 0.3 0.055 13.7 0.1 2.3 2 0 0 2 2 2 1 SOUL heme-binding protein adh_short PF00106.25 OAP60005.1 - 2.3e-28 99.0 0.0 7.8e-27 94.0 0.0 2.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP60005.1 - 2e-16 60.3 0.0 3.6e-14 52.9 0.0 2.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 OAP60005.1 - 0.00022 20.7 0.0 0.00027 20.4 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.6 OAP60005.1 - 0.0021 18.0 0.1 0.0035 17.3 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAP60005.1 - 0.0022 17.5 0.8 0.47 9.9 0.0 2.9 3 0 0 3 3 3 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 OAP60005.1 - 0.0081 15.7 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Retinal PF15449.6 OAP60005.1 - 0.018 12.9 0.6 0.024 12.5 0.6 1.0 1 0 0 1 1 1 0 Retinal protein MTP18 PF10558.9 OAP60007.1 - 9.6e-82 273.0 0.2 1.2e-81 272.7 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) ATP19 PF11022.8 OAP60008.1 - 2.7e-26 91.7 0.0 3.2e-26 91.5 0.0 1.1 1 0 0 1 1 1 1 ATP synthase subunit K Peroxin-13_N PF04088.13 OAP60008.1 - 0.057 13.7 0.5 0.52 10.6 0.0 2.0 2 0 0 2 2 2 0 Peroxin 13, N-terminal region AAT PF03417.16 OAP60009.1 - 4.7e-28 98.4 0.0 6e-28 98.1 0.0 1.1 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase ACPS PF01648.20 OAP60010.1 - 2.7e-12 46.8 0.0 4.8e-12 46.0 0.0 1.4 1 1 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily 4PPT_N PF17837.1 OAP60010.1 - 0.0025 17.9 0.5 2.7 8.2 0.1 2.5 2 0 0 2 2 2 2 4'-phosphopantetheinyl transferase N-terminal domain Methyltransf_3 PF01596.17 OAP60011.1 - 1.8e-25 89.4 0.0 5.9e-18 64.8 0.0 2.1 1 1 1 2 2 2 2 O-methyltransferase Methyltransf_24 PF13578.6 OAP60011.1 - 9.4e-09 36.3 0.0 2.7e-08 34.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 OAP60011.1 - 0.049 13.6 0.0 0.087 12.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Hva1_TUDOR PF11160.8 OAP60012.1 - 1.1e-06 28.6 0.9 1.9e-06 28.0 0.9 1.5 1 1 0 1 1 1 1 Hypervirulence associated proteins TUDOR domain Brix PF04427.18 OAP60012.1 - 0.028 14.5 0.0 0.029 14.5 0.0 1.0 1 0 0 1 1 1 0 Brix domain Sep15_SelM PF08806.11 OAP60012.1 - 0.17 12.1 0.0 0.22 11.7 0.0 1.2 1 0 0 1 1 1 0 Sep15/SelM redox domain NACHT PF05729.12 OAP60013.1 - 2.2e-07 31.0 0.1 7.7e-07 29.2 0.1 2.0 1 0 0 1 1 1 1 NACHT domain SesA PF17107.5 OAP60013.1 - 3.6e-06 27.2 2.2 1.2e-05 25.5 0.1 2.7 3 0 0 3 3 3 1 N-terminal domain on NACHT_NTPase and P-loop NTPases AAA_22 PF13401.6 OAP60013.1 - 0.001 19.3 0.0 0.0085 16.4 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_23 PF13476.6 OAP60013.1 - 0.038 14.5 0.0 0.038 14.5 0.0 2.5 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.27 OAP60013.1 - 0.04 14.4 0.0 0.13 12.8 0.0 1.8 1 0 0 1 1 1 0 ABC transporter cobW PF02492.19 OAP60013.1 - 0.074 12.6 0.0 0.83 9.2 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.6 OAP60013.1 - 0.14 11.9 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Erp_C PF06780.11 OAP60013.1 - 0.16 11.9 0.2 0.9 9.6 0.1 2.2 2 0 0 2 2 2 0 Erp protein C-terminus Lipoxygenase PF00305.19 OAP60015.1 - 6.7e-28 97.5 0.7 1.2e-27 96.7 0.7 1.3 1 1 0 1 1 1 1 Lipoxygenase EthD PF07110.11 OAP60016.1 - 3.4e-14 53.7 0.5 4.3e-14 53.4 0.5 1.1 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 OAP60016.1 - 0.0015 19.0 0.1 0.0022 18.4 0.1 1.2 1 0 0 1 1 1 1 Methylmuconolactone methyl-isomerase adh_short PF00106.25 OAP60017.1 - 3.2e-39 134.4 0.0 3.9e-39 134.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP60017.1 - 5.9e-30 104.5 0.0 8.4e-30 104.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP60017.1 - 5.4e-05 23.2 0.0 0.00027 20.9 0.0 1.8 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 OAP60017.1 - 0.014 14.8 0.0 0.02 14.4 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OAP60017.1 - 0.047 12.7 0.0 0.073 12.1 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family MFS_1 PF07690.16 OAP60018.1 - 2.8e-24 85.7 35.1 2.8e-24 85.7 35.1 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily ABM PF03992.16 OAP60019.1 - 4.4e-09 36.3 0.0 7.6e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase DUF5470 PF17564.2 OAP60020.1 - 0.15 12.2 0.2 0.29 11.3 0.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5470) PigN PF04987.14 OAP60021.1 - 1.9e-161 538.0 37.2 2.7e-161 537.5 37.2 1.2 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Sulfatase PF00884.23 OAP60021.1 - 1.4e-07 31.3 0.1 2.1e-07 30.7 0.1 1.3 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 OAP60021.1 - 3e-07 30.4 4.8 7.8e-06 25.7 4.8 2.1 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 OAP60021.1 - 1.8e-05 24.3 0.0 2.8e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Alk_phosphatase PF00245.20 OAP60021.1 - 0.16 10.9 0.0 0.26 10.2 0.0 1.3 1 0 0 1 1 1 0 Alkaline phosphatase EAP30 PF04157.16 OAP60022.1 - 6.4e-41 140.2 0.1 7.5e-41 140.0 0.1 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family EutK_C PF16365.5 OAP60022.1 - 0.08 13.0 0.7 0.17 11.9 0.3 1.8 2 0 0 2 2 2 0 Ethanolamine utilization protein EutK C-terminus SAC3_GANP PF03399.16 OAP60023.1 - 6e-22 78.4 0.1 2.3e-10 40.3 0.0 2.2 2 0 0 2 2 2 2 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 OAP60023.1 - 4.8e-05 23.4 0.0 0.00011 22.1 0.0 1.6 1 1 0 1 1 1 1 CSN8/PSMD8/EIF3K family SH3_1 PF00018.28 OAP60024.1 - 9.1e-24 82.8 0.2 1.9e-10 40.2 0.0 3.3 4 0 0 4 4 4 2 SH3 domain PX PF00787.24 OAP60024.1 - 4.7e-12 45.9 0.0 1.1e-11 44.7 0.0 1.6 1 0 0 1 1 1 1 PX domain SH3_9 PF14604.6 OAP60024.1 - 5.1e-12 45.5 2.5 5.2e-06 26.2 0.0 2.9 3 0 0 3 3 3 2 Variant SH3 domain SH3_2 PF07653.17 OAP60024.1 - 6.7e-09 35.3 0.0 1.1e-05 25.0 0.0 2.9 2 0 0 2 2 2 2 Variant SH3 domain PB1 PF00564.24 OAP60024.1 - 3.7e-08 33.2 0.3 6.7e-08 32.4 0.3 1.4 1 0 0 1 1 1 1 PB1 domain AP2 PF00847.20 OAP60024.1 - 0.0094 16.2 0.0 0.017 15.3 0.0 1.4 1 0 0 1 1 1 1 AP2 domain AFG1_ATPase PF03969.16 OAP60025.1 - 1.1e-98 330.5 0.0 7.3e-94 314.6 0.0 2.2 2 0 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.6 OAP60025.1 - 8.8e-05 23.0 1.2 0.93 9.8 0.0 3.7 3 1 1 4 4 4 2 AAA ATPase domain AAA_14 PF13173.6 OAP60025.1 - 0.0013 18.8 0.0 0.0035 17.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain Bac_DnaA PF00308.18 OAP60025.1 - 0.0022 17.9 0.5 1.6 8.5 0.1 2.5 2 0 0 2 2 2 2 Bacterial dnaA protein AAA_22 PF13401.6 OAP60025.1 - 0.0058 16.9 0.2 0.049 13.9 0.0 2.7 2 2 0 2 2 2 1 AAA domain AAA_5 PF07728.14 OAP60025.1 - 0.015 15.3 0.0 0.2 11.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) MCM_lid PF17855.1 OAP60025.1 - 0.021 15.2 0.6 0.068 13.6 0.6 1.9 1 0 0 1 1 1 0 MCM AAA-lid domain AAA PF00004.29 OAP60025.1 - 0.029 14.8 1.8 0.09 13.2 0.0 2.7 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 OAP60025.1 - 0.076 13.0 0.0 0.2 11.7 0.0 1.6 1 1 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sacchrp_dh_NADP PF03435.18 OAP60025.1 - 0.099 12.9 0.1 0.44 10.8 0.0 2.1 2 1 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain RNA_helicase PF00910.22 OAP60025.1 - 0.14 12.5 0.0 0.55 10.6 0.0 2.0 1 1 0 1 1 1 0 RNA helicase Zw10 PF06248.13 OAP60025.1 - 0.24 9.9 0.7 11 4.4 0.2 2.3 2 0 0 2 2 2 0 Centromere/kinetochore Zw10 DUF948 PF06103.11 OAP60025.1 - 1.7 9.0 5.9 0.46 10.8 1.9 2.2 4 0 0 4 4 3 0 Bacterial protein of unknown function (DUF948) LysM PF01476.20 OAP60026.1 - 0.045 13.8 0.0 0.076 13.1 0.0 1.4 1 0 0 1 1 1 0 LysM domain Cys_Met_Meta_PP PF01053.20 OAP60028.1 - 4.6e-138 459.9 0.0 5.4e-138 459.7 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 OAP60028.1 - 1.3e-06 27.9 0.0 1.9e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 OAP60028.1 - 1.5e-05 24.1 0.0 3e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 OAP60028.1 - 0.00019 20.9 0.1 0.0004 19.8 0.0 1.5 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family GDC-P PF02347.16 OAP60028.1 - 0.0043 15.9 0.0 0.0066 15.3 0.0 1.2 1 0 0 1 1 1 1 Glycine cleavage system P-protein B12-binding PF02310.19 OAP60028.1 - 0.055 13.5 0.0 0.53 10.3 0.0 2.2 2 0 0 2 2 2 0 B12 binding domain PHP PF02811.19 OAP60029.1 - 2.9e-12 47.2 0.2 1.6e-11 44.8 0.3 2.1 2 1 0 2 2 2 1 PHP domain FKBP_C PF00254.28 OAP60030.1 - 1.5e-13 50.9 0.0 1.8e-13 50.6 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Zeta_toxin PF06414.12 OAP60031.1 - 0.008 15.5 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin PRK PF00485.18 OAP60031.1 - 0.02 14.7 0.0 0.038 13.7 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family KAP_NTPase PF07693.14 OAP60031.1 - 0.033 13.4 0.0 0.053 12.7 0.0 1.4 1 0 0 1 1 1 0 KAP family P-loop domain AAA_18 PF13238.6 OAP60031.1 - 0.12 12.9 0.0 0.21 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 OAP60031.1 - 0.19 10.9 0.0 1.4 8.0 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain adh_short PF00106.25 OAP60032.1 - 1.1e-85 286.0 8.4 2.7e-47 160.8 0.4 2.6 3 0 0 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAP60032.1 - 3.4e-65 219.9 7.3 2.2e-35 122.3 0.1 2.9 2 2 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase MaoC_dehydratas PF01575.19 OAP60032.1 - 1.4e-31 108.6 0.0 3.5e-31 107.3 0.0 1.7 2 0 0 2 2 2 1 MaoC like domain KR PF08659.10 OAP60032.1 - 1.8e-27 96.4 3.0 1.1e-12 48.3 0.1 2.3 2 0 0 2 2 2 2 KR domain THF_DHG_CYH_C PF02882.19 OAP60032.1 - 0.00096 18.5 1.4 0.0044 16.3 0.4 2.2 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.18 OAP60032.1 - 0.61 9.9 5.8 6.1 6.7 1.1 2.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAM25 PF15825.5 OAP60032.1 - 3 8.3 9.9 1.8 8.9 0.5 3.4 3 0 0 3 3 3 0 FAM25 family IBR PF01485.21 OAP60033.1 - 1.8e-05 24.8 4.2 1.8e-05 24.8 4.2 4.7 4 1 1 5 5 5 2 IBR domain, a half RING-finger domain Ac81 PF05820.11 OAP60033.1 - 0.026 14.1 1.0 0.066 12.8 0.2 1.9 2 0 0 2 2 2 0 Baculoviridae AC81 CUE PF02845.16 OAP60033.1 - 0.19 11.5 0.2 0.64 9.8 0.2 2.0 1 0 0 1 1 1 0 CUE domain zinc_ribbon_9 PF14369.6 OAP60033.1 - 0.56 10.5 0.0 0.56 10.5 0.0 4.3 4 1 0 4 4 4 0 zinc-ribbon Aldo_ket_red PF00248.21 OAP60034.1 - 4.5e-57 193.5 0.0 5.9e-57 193.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Bclx_interact PF08945.10 OAP60034.1 - 0.095 12.5 0.3 0.25 11.2 0.3 1.7 1 0 0 1 1 1 0 Bcl-x interacting, BH3 domain Pam16 PF03656.13 OAP60035.1 - 3.7e-32 111.0 0.6 4.5e-32 110.7 0.6 1.0 1 0 0 1 1 1 1 Pam16 Ribosomal_S2 PF00318.20 OAP60035.1 - 0.097 11.9 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein S2 Pex24p PF06398.11 OAP60036.1 - 8.4e-94 314.5 0.1 1.2e-93 314.1 0.1 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Tmemb_cc2 PF10267.9 OAP60036.1 - 1.1 8.3 3.1 20 4.2 0.0 2.1 2 0 0 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein Chlorosome_CsmC PF11098.8 OAP60037.1 - 0.018 15.0 4.9 0.026 14.5 4.9 1.3 1 0 0 1 1 1 0 Chlorosome envelope protein C Coiled PF05710.12 OAP60037.1 - 2.3 9.1 12.1 1.3 9.9 9.9 1.6 1 1 1 2 2 2 0 Coiled coil VPS13_C PF16909.5 OAP60037.1 - 8.3 6.1 6.5 9.2 6.0 4.4 1.8 1 1 0 1 1 1 0 Vacuolar-sorting-associated 13 protein C-terminal Lipase_3 PF01764.25 OAP60038.1 - 8.6e-05 22.4 0.0 0.00018 21.4 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 OAP60038.1 - 0.02 15.5 0.5 0.074 13.6 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAP60038.1 - 0.093 12.0 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 VPS9 PF02204.18 OAP60039.1 - 3.8e-25 88.1 0.0 6.4e-25 87.4 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 OAP60039.1 - 0.041 14.2 0.3 0.52 10.7 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5601) RcsF PF16358.5 OAP60039.1 - 0.051 13.6 0.0 0.2 11.8 0.0 2.0 1 0 0 1 1 1 0 RcsF lipoprotein JAKMIP_CC3 PF16034.5 OAP60039.1 - 0.066 13.2 0.4 2.1 8.3 0.0 2.6 2 0 0 2 2 2 0 JAKMIP CC3 domain ECM11 PF15463.6 OAP60040.1 - 5e-25 88.6 0.3 5e-25 88.6 0.3 2.4 3 0 0 3 3 3 1 Extracellular mutant protein 11 PAS_3 PF08447.12 OAP60041.1 - 1e-14 54.6 0.0 3.5e-11 43.2 0.1 2.4 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 OAP60041.1 - 2.6e-07 30.8 0.0 0.00081 19.6 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS PF00989.25 OAP60041.1 - 6.3e-06 26.2 0.0 0.0033 17.4 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.10 OAP60041.1 - 6.3e-05 23.2 0.0 0.0086 16.3 0.0 3.0 3 0 0 3 3 3 1 PAS fold PAS_11 PF14598.6 OAP60041.1 - 0.0003 20.9 0.0 0.0072 16.4 0.0 2.2 2 0 0 2 2 2 1 PAS domain Bac_luciferase PF00296.20 OAP60042.1 - 5.5e-56 190.3 0.2 9.2e-56 189.5 0.2 1.2 1 0 0 1 1 1 1 Luciferase-like monooxygenase Methyltrn_RNA_3 PF02598.17 OAP60042.1 - 0.12 11.8 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 Putative RNA methyltransferase FMO-like PF00743.19 OAP60044.1 - 7.2e-15 54.4 0.0 1.8e-14 53.1 0.0 1.6 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OAP60044.1 - 1.8e-10 40.9 0.0 6.1e-10 39.2 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 OAP60044.1 - 2.5e-08 33.5 0.0 1.5e-07 31.0 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAP60044.1 - 1e-06 28.2 0.0 9.5e-06 25.0 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAP60044.1 - 2.2e-06 27.5 1.4 3.2e-05 23.7 1.4 2.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 OAP60044.1 - 3.4e-06 26.4 0.2 9.3e-05 21.7 0.0 2.4 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 OAP60044.1 - 0.0026 17.0 0.7 0.0044 16.3 0.0 1.6 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.6 OAP60044.1 - 0.011 15.7 0.0 0.65 10.0 0.0 2.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding Mqo PF06039.15 OAP60044.1 - 0.14 10.7 0.4 7.3 5.0 0.1 2.2 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) HI0933_like PF03486.14 OAP60044.1 - 0.63 8.7 1.2 1.2 7.7 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein MFS_1 PF07690.16 OAP60045.1 - 3.3e-29 101.9 34.0 6.7e-29 100.9 33.9 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Trep_Strep PF09605.10 OAP60045.1 - 1.1 9.2 16.2 0.34 10.9 0.7 3.5 3 0 0 3 3 3 0 Hypothetical bacterial integral membrane protein (Trep_Strep) Bac_luciferase PF00296.20 OAP60046.1 - 5.3e-58 196.9 0.0 7e-58 196.5 0.0 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase MFS_1 PF07690.16 OAP60047.1 - 5.5e-30 104.5 23.6 5.5e-30 104.5 23.6 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily BPL_N PF09825.9 OAP60048.1 - 5.3e-147 489.8 0.0 6.9e-147 489.4 0.0 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.19 OAP60048.1 - 7.6e-21 74.4 0.1 1.5e-20 73.4 0.1 1.5 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.17 OAP60048.1 - 2.1e-05 24.3 0.0 4.4e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain CHCH PF06747.13 OAP60049.1 - 1.6e-06 28.1 9.1 2.6e-06 27.4 9.1 1.3 1 0 0 1 1 1 1 CHCH domain CX9C PF16860.5 OAP60049.1 - 0.0034 17.3 1.2 0.22 11.6 0.3 2.2 2 0 0 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Cmc1 PF08583.10 OAP60049.1 - 0.081 13.0 6.5 0.43 10.6 1.0 2.2 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like COX17 PF05051.13 OAP60049.1 - 0.12 12.7 3.2 0.18 12.2 3.2 1.2 1 0 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) Mgm101p PF06420.12 OAP60050.1 - 5.6e-86 286.3 0.0 7.1e-86 286.0 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 Usp PF00582.26 OAP60051.1 - 4.9e-21 75.7 0.0 1.6e-20 74.1 0.0 1.9 1 0 0 1 1 1 1 Universal stress protein family HEPPP_synt_1 PF07307.11 OAP60051.1 - 0.01 15.5 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 1 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 ABA_GPCR PF12430.8 OAP60052.1 - 5.1e-53 179.5 3.8 5.1e-53 179.5 3.8 2.1 2 0 0 2 2 2 1 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 OAP60052.1 - 2.5e-21 75.5 0.0 2.5e-21 75.5 0.0 3.0 4 0 0 4 4 4 1 The Golgi pH Regulator (GPHR) Family N-terminal MitoNEET_N PF10660.9 OAP60052.1 - 0.013 15.5 0.1 0.051 13.6 0.1 2.1 1 0 0 1 1 1 0 Iron-containing outer mitochondrial membrane protein N-terminus DUF1751 PF08551.10 OAP60052.1 - 2.4 8.8 5.2 6.7 7.3 0.1 3.2 2 1 0 3 3 3 0 Eukaryotic integral membrane protein (DUF1751) Syntaxin-18_N PF10496.9 OAP60053.1 - 1e-08 35.3 0.6 3.8e-08 33.5 0.1 2.2 2 0 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.19 OAP60053.1 - 6.2e-07 29.3 0.2 1.7e-06 27.9 0.0 1.8 2 0 0 2 2 2 1 SNARE domain DUF5089 PF17002.5 OAP60053.1 - 0.037 13.9 4.4 1.5 8.6 0.0 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF5089) BLOC1_2 PF10046.9 OAP60053.1 - 0.36 11.1 4.7 21 5.5 0.2 3.3 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF16 PF01519.16 OAP60053.1 - 1 9.9 7.8 3 8.4 0.5 3.3 3 0 0 3 3 3 0 Protein of unknown function DUF16 Aminotran_1_2 PF00155.21 OAP60054.1 - 1.6e-83 280.9 0.0 1.8e-83 280.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DUF3446 PF11928.8 OAP60055.1 - 9.4 6.6 9.4 0.93 9.8 1.0 2.4 2 0 0 2 2 2 0 Early growth response N-terminal domain Neur_chan_memb PF02932.16 OAP60056.1 - 4.9 7.1 6.5 6.8 6.7 6.5 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region MS_channel PF00924.18 OAP60057.1 - 4e-20 72.2 0.8 7e-20 71.5 0.8 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.32 OAP60057.1 - 0.0089 15.5 0.3 0.026 14.1 0.3 1.9 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 OAP60057.1 - 0.095 12.6 0.8 0.26 11.2 0.8 1.7 1 0 0 1 1 1 0 EF-hand domain pair Serglycin PF04360.12 OAP60058.1 - 0.055 13.4 9.1 0.13 12.2 9.1 1.7 1 0 0 1 1 1 0 Serglycin Med12 PF09497.10 OAP60061.1 - 2.6e-26 91.7 0.1 7e-26 90.3 0.1 1.8 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 Zn_clus PF00172.18 OAP60063.1 - 4.7e-08 33.0 10.3 7.9e-08 32.3 10.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 OAP60063.1 - 1.4e-06 27.4 1.7 2.5e-06 26.6 1.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain RTA1 PF04479.13 OAP60064.1 - 6e-71 238.3 4.2 8.9e-71 237.8 4.2 1.2 1 0 0 1 1 1 1 RTA1 like protein SFTA2 PF15210.6 OAP60064.1 - 0.44 10.5 1.7 0.55 10.2 0.1 1.9 2 0 0 2 2 2 0 Surfactant-associated protein 2 GST_N_3 PF13417.6 OAP60065.1 - 6.5e-15 55.3 0.0 1.1e-14 54.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 OAP60065.1 - 2.2e-11 43.9 0.0 3.9e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OAP60065.1 - 1.3e-09 38.2 0.0 2.2e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OAP60065.1 - 5.3e-08 33.0 0.0 1.5e-07 31.5 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OAP60065.1 - 7.6e-07 29.2 0.0 1.4e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OAP60065.1 - 2.1e-06 27.6 0.1 3.8e-06 26.8 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 OAP60065.1 - 0.022 14.6 0.3 0.041 13.7 0.3 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Cupin_2 PF07883.11 OAP60066.1 - 2.1e-25 88.2 0.0 9.4e-13 47.7 0.0 2.4 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.19 OAP60066.1 - 2e-06 27.8 0.0 0.006 16.5 0.0 2.2 2 0 0 2 2 2 2 AraC-like ligand binding domain CENP-C_C PF11699.8 OAP60066.1 - 3.8e-05 23.8 0.0 0.00018 21.7 0.0 1.9 2 0 0 2 2 2 1 Mif2/CENP-C like ARD PF03079.14 OAP60066.1 - 0.0018 18.5 0.0 1.5 9.0 0.0 2.2 2 0 0 2 2 2 2 ARD/ARD' family DMSP_lyase PF16867.5 OAP60066.1 - 0.0025 17.5 0.1 0.0069 16.0 0.0 1.7 2 0 0 2 2 2 1 Dimethlysulfonioproprionate lyase Cupin_3 PF05899.12 OAP60066.1 - 0.0063 16.2 0.0 2.6 7.8 0.0 2.6 3 0 0 3 3 3 2 Protein of unknown function (DUF861) DUF4437 PF14499.6 OAP60066.1 - 0.0073 15.5 0.1 0.01 15.0 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4437) Aldedh PF00171.22 OAP60067.1 - 1.2e-125 419.7 0.1 1.4e-125 419.5 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Fungal_trans PF04082.18 OAP60068.1 - 1.3e-33 116.1 0.0 2.1e-33 115.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Coatomer_WDAD PF04053.14 OAP60069.1 - 1.8e-165 551.4 0.0 5.2e-165 549.8 0.0 1.7 2 1 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.32 OAP60069.1 - 3.7e-33 113.0 6.2 1e-05 26.2 0.0 8.8 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAP60069.1 - 4.4e-09 36.5 0.1 1.1 9.6 0.0 5.9 5 2 2 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OAP60069.1 - 2.9e-05 22.9 2.3 0.066 11.8 0.5 3.5 2 1 1 3 3 3 1 Nucleoporin Nup120/160 Guanylate_cyc PF00211.20 OAP60070.1 - 7.9e-21 74.5 0.0 3.6e-19 69.1 0.0 2.1 1 1 1 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain Aconitase PF00330.20 OAP60071.1 - 4.2e-167 556.8 0.1 5.1e-167 556.5 0.1 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 OAP60071.1 - 1.7e-41 141.6 0.0 3.5e-41 140.6 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF3394 PF11874.8 OAP60071.1 - 0.18 11.5 0.0 18 5.0 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3394) RGS PF00615.19 OAP60072.1 - 8.1e-30 103.5 0.1 3.4e-29 101.5 0.1 2.0 2 0 0 2 2 2 1 Regulator of G protein signaling domain DEP PF00610.21 OAP60072.1 - 5.4e-22 77.6 0.0 4.6e-18 65.0 0.0 3.3 3 0 0 3 3 3 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) CDC73_C PF05179.14 OAP60073.1 - 1.1e-55 187.7 0.0 1.9e-55 186.9 0.0 1.4 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal OsmC PF02566.19 OAP60075.1 - 1.8e-16 60.5 0.0 2.7e-16 59.9 0.0 1.3 1 0 0 1 1 1 1 OsmC-like protein MFS_1 PF07690.16 OAP60076.1 - 5.5e-11 42.0 43.4 5.5e-11 42.0 43.4 3.0 1 1 2 3 3 3 2 Major Facilitator Superfamily G-alpha PF00503.20 OAP60077.1 - 1.2e-35 123.3 0.7 1.7e-35 122.9 0.2 1.4 2 0 0 2 2 2 1 G-protein alpha subunit Helo_like_N PF17111.5 OAP60077.1 - 0.0045 16.4 1.0 0.0095 15.3 1.0 1.6 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins Sec8_exocyst PF04048.14 OAP60077.1 - 0.061 13.2 0.3 0.18 11.7 0.1 2.0 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain Glutaredoxin PF00462.24 OAP60078.1 - 1e-18 67.3 0.0 2.7e-16 59.5 0.0 2.5 2 0 0 2 2 2 2 Glutaredoxin Thioredoxin PF00085.20 OAP60078.1 - 4e-12 46.0 0.0 1.6e-11 44.1 0.0 1.9 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_8 PF13905.6 OAP60078.1 - 0.032 14.6 0.0 0.92 9.9 0.0 2.4 1 1 1 2 2 2 0 Thioredoxin-like AhpC-TSA PF00578.21 OAP60078.1 - 0.2 11.6 0.0 0.53 10.2 0.0 1.6 2 0 0 2 2 2 0 AhpC/TSA family TauD PF02668.16 OAP60079.1 - 1.9e-31 109.8 0.3 1.6e-29 103.5 0.3 2.2 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 OAP60079.1 - 0.0029 18.2 0.0 0.009 16.6 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF971) Turandot PF07240.11 OAP60079.1 - 0.096 12.7 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Stress-inducible humoral factor Turandot WD40 PF00400.32 OAP60080.1 - 1.4e-13 51.1 4.3 0.12 13.3 0.3 6.6 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAP60080.1 - 0.012 15.9 0.1 3 8.2 0.0 3.7 4 2 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain HAUS-augmin3 PF14932.6 OAP60081.1 - 0.029 14.0 0.3 0.05 13.2 0.3 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 AAA_13 PF13166.6 OAP60081.1 - 0.031 13.0 0.4 0.051 12.2 0.4 1.2 1 0 0 1 1 1 0 AAA domain DUF4407 PF14362.6 OAP60081.1 - 0.31 10.4 1.6 0.78 9.0 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Acetyltransf_3 PF13302.7 OAP60082.1 - 1.4e-14 54.9 0.0 1.9e-14 54.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAP60082.1 - 0.098 12.9 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family p450 PF00067.22 OAP60083.1 - 7.6e-58 196.4 0.0 1e-57 196.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 LSM PF01423.22 OAP60084.1 - 6.1e-21 73.9 0.5 6.7e-21 73.8 0.5 1.0 1 0 0 1 1 1 1 LSM domain Peptidase_M1_N PF17900.1 OAP60085.1 - 4.4e-05 23.7 0.0 0.17 12.1 0.0 2.4 2 0 0 2 2 2 2 Peptidase M1 N-terminal domain Ntox28 PF15605.6 OAP60085.1 - 0.049 13.9 0.4 1.1 9.5 0.0 2.6 2 0 0 2 2 2 0 Bacterial toxin 28 CDP-OH_P_transf PF01066.21 OAP60086.1 - 4.2e-16 59.5 0.3 4.2e-16 59.5 0.3 3.2 3 1 0 3 3 3 1 CDP-alcohol phosphatidyltransferase Holin_SPP1 PF04688.13 OAP60086.1 - 0.084 13.0 0.0 0.58 10.4 0.0 2.1 1 1 1 2 2 2 0 SPP1 phage holin HpcH_HpaI PF03328.14 OAP60087.1 - 6.5e-43 146.4 0.0 9e-43 146.0 0.0 1.2 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 OAP60087.1 - 5.4e-14 52.1 0.1 1.4e-08 34.2 0.0 2.1 1 1 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold Pkinase PF00069.25 OAP60088.1 - 1.7e-69 234.1 0.0 2.4e-69 233.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP60088.1 - 7.1e-33 114.0 0.0 1.1e-32 113.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 OAP60088.1 - 1.5e-08 35.2 0.2 1.5e-08 35.2 0.2 1.9 2 0 0 2 2 2 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 OAP60088.1 - 5.6e-06 25.5 0.0 8.3e-06 25.0 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 OAP60088.1 - 0.0065 15.8 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like ZZ PF00569.17 OAP60089.1 - 2.3e-09 36.9 5.5 4.2e-09 36.1 5.5 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type SWIRM PF04433.17 OAP60089.1 - 6.3e-09 36.1 0.0 1.7e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.31 OAP60089.1 - 1.1e-08 35.1 1.7 1.5e-08 34.7 0.0 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain zf-UBR PF02207.20 OAP60089.1 - 2.1 8.5 6.6 5.9 7.1 6.6 1.7 1 1 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) Caudo_TAP PF02413.17 OAP60090.1 - 0.044 13.9 0.4 0.058 13.5 0.4 1.2 1 0 0 1 1 1 0 Caudovirales tail fibre assembly protein, lambda gpK GDC-P PF02347.16 OAP60091.1 - 2.8e-178 593.2 0.0 3.5e-165 550.0 0.0 2.6 3 0 0 3 3 3 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.21 OAP60091.1 - 3.2e-07 29.9 0.0 7.7e-07 28.7 0.0 1.6 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 OAP60091.1 - 4.1e-07 29.3 0.2 0.00014 21.0 0.0 2.3 2 0 0 2 2 2 2 Aminotransferase class-V SepSecS PF05889.13 OAP60091.1 - 0.022 13.4 0.1 0.1 11.3 0.0 2.1 3 0 0 3 3 3 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS DegT_DnrJ_EryC1 PF01041.17 OAP60091.1 - 0.13 11.6 0.0 0.25 10.6 0.0 1.4 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Senescence PF06911.12 OAP60092.1 - 0.076 13.3 3.2 0.13 12.6 3.2 1.4 1 1 0 1 1 1 0 Senescence-associated protein VPS13_C PF16909.5 OAP60092.1 - 0.12 12.2 4.4 0.11 12.3 2.3 1.8 1 1 1 2 2 2 0 Vacuolar-sorting-associated 13 protein C-terminal Peptidase_U32_C PF16325.5 OAP60093.1 - 0.033 14.4 0.0 0.063 13.6 0.0 1.4 1 0 0 1 1 1 0 Peptidase family U32 C-terminal domain DUF4889 PF16230.5 OAP60093.1 - 0.26 11.5 0.7 0.46 10.7 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4889) MAGE_N PF12440.8 OAP60094.1 - 2.1 9.1 13.4 3.6 8.3 13.4 1.4 1 0 0 1 1 1 0 Melanoma associated antigen family N terminal Sporozoite_P67 PF05642.11 OAP60094.1 - 3.1 5.8 10.7 3.6 5.5 10.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen BES1_N PF05687.13 OAP60094.1 - 4.9 7.5 7.4 7.1 7.0 7.4 1.2 1 0 0 1 1 1 0 BES1/BZR1 plant transcription factor, N-terminal Arylsulfotran_2 PF14269.6 OAP60095.1 - 7.5e-51 173.3 2.3 1.1e-50 172.7 2.3 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 OAP60095.1 - 6.4e-21 74.7 0.3 1.6e-20 73.3 0.3 1.6 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) F-box PF00646.33 OAP60096.1 - 0.00038 20.2 0.2 0.0011 18.8 0.2 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 OAP60096.1 - 0.0056 16.5 1.0 0.02 14.8 0.3 2.2 2 0 0 2 2 2 1 F-box-like UFD1 PF03152.14 OAP60097.1 - 1.3e-26 93.1 0.0 1.6e-22 79.8 0.0 3.3 2 1 0 2 2 2 2 Ubiquitin fusion degradation protein UFD1 MCR PF18509.1 OAP60097.1 - 0.0064 16.0 3.5 0.022 14.3 0.4 2.9 2 0 0 2 2 2 1 Magnetochrome domain AZUL PF16558.5 OAP60097.1 - 0.012 15.8 0.1 0.035 14.4 0.1 1.8 1 0 0 1 1 1 0 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A zf-UDP PF14569.6 OAP60097.1 - 0.025 14.7 5.6 0.065 13.4 0.6 2.8 2 0 0 2 2 2 0 Zinc-binding RING-finger zf-C2H2_4 PF13894.6 OAP60097.1 - 1.6 9.8 14.7 0.72 10.9 0.3 4.6 4 0 0 4 4 4 0 C2H2-type zinc finger Ring_hydroxyl_A PF00848.19 OAP60099.1 - 1.3e-25 90.6 3.9 7.8e-25 88.1 3.9 2.1 1 1 0 1 1 1 1 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.26 OAP60099.1 - 2.7e-14 52.9 0.1 5.1e-14 52.0 0.1 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Fungal_trans_2 PF11951.8 OAP60100.1 - 5.1e-37 127.6 0.1 4.1e-36 124.6 0.1 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP60100.1 - 0.00015 21.9 9.2 0.00015 21.9 9.2 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PhyH PF05721.13 OAP60101.1 - 3.1e-25 89.7 0.0 4.2e-25 89.3 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 OAP60101.1 - 0.14 10.9 0.0 0.22 10.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1479) AA_permease_2 PF13520.6 OAP60102.1 - 4e-40 137.9 48.9 5.1e-40 137.6 48.9 1.0 1 0 0 1 1 1 1 Amino acid permease ABC1 PF03109.16 OAP60104.1 - 3e-21 75.8 0.0 1.3e-11 44.7 0.0 2.9 2 0 0 2 2 2 2 ABC1 family Raf1_HTH PF18579.1 OAP60104.1 - 0.0015 18.2 0.0 0.0031 17.2 0.0 1.5 1 0 0 1 1 1 1 Rubisco accumulation factor 1 helix turn helix domain APH PF01636.23 OAP60104.1 - 0.16 11.8 0.9 0.38 10.6 0.1 2.1 2 1 1 3 3 3 0 Phosphotransferase enzyme family MFS_1 PF07690.16 OAP60105.1 - 1.1e-33 116.7 33.0 1.5e-33 116.2 33.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3925 PF13063.6 OAP60105.1 - 0.041 14.1 2.2 0.17 12.1 2.2 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3925) Ciart PF15673.5 OAP60107.1 - 0.12 11.7 0.2 0.19 11.0 0.2 1.2 1 0 0 1 1 1 0 Circadian-associated transcriptional repressor LisH_TPL PF17814.1 OAP60107.1 - 0.16 11.7 0.2 0.49 10.1 0.0 1.9 2 0 0 2 2 2 0 LisH-like dimerisation domain MFS_1 PF07690.16 OAP60110.1 - 2.1e-15 56.5 20.2 2.6e-12 46.4 5.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily CcmH PF03918.14 OAP60110.1 - 0.13 11.6 0.5 4.6 6.5 0.0 2.7 3 0 0 3 3 3 0 Cytochrome C biogenesis protein His_Phos_2 PF00328.22 OAP60111.1 - 2e-40 139.3 0.0 3.9e-40 138.4 0.0 1.4 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Voltage_CLC PF00654.20 OAP60112.1 - 0.09 12.0 6.3 0.052 12.8 1.3 2.0 1 1 1 2 2 2 0 Voltage gated chloride channel Tetraspanin PF00335.20 OAP60112.1 - 5 6.8 9.8 0.45 10.2 2.2 1.9 1 1 1 2 2 2 0 Tetraspanin family CcmD PF04995.14 OAP60112.1 - 7.6 6.7 0.0 7.6 6.7 0.0 3.2 3 1 0 3 3 3 0 Heme exporter protein D (CcmD) FAD_binding_3 PF01494.19 OAP60114.1 - 6.3e-12 45.4 1.6 2e-05 24.0 0.2 3.3 3 0 0 3 3 3 3 FAD binding domain DAO PF01266.24 OAP60114.1 - 2.1e-05 24.3 0.1 3.7e-05 23.5 0.1 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 OAP60114.1 - 0.0076 16.2 0.1 16 5.5 0.0 3.4 3 0 0 3 3 3 1 FAD-NAD(P)-binding MTBP_C PF14920.6 OAP60114.1 - 0.01 15.6 1.0 0.01 15.6 1.0 1.8 2 0 0 2 2 2 0 MDM2-binding Pyr_redox_2 PF07992.14 OAP60114.1 - 0.012 14.8 0.1 3.3 6.8 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAP60114.1 - 0.014 15.6 0.0 0.066 13.4 0.0 2.3 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Herpes_UL14 PF03580.14 OAP60114.1 - 0.17 12.1 1.6 0.31 11.3 1.6 1.3 1 0 0 1 1 1 0 Herpesvirus UL14-like protein She9_MDM33 PF05546.11 OAP60114.1 - 0.56 10.0 3.7 0.92 9.3 3.7 1.2 1 0 0 1 1 1 0 She9 / Mdm33 family IQ PF00612.27 OAP60115.1 - 5.4e-05 22.6 0.7 0.00015 21.3 0.7 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif APG6_N PF17675.1 OAP60115.1 - 0.45 11.0 10.2 0.038 14.5 3.8 2.4 3 0 0 3 3 3 0 Apg6 coiled-coil region MCU PF04678.13 OAP60115.1 - 7.9 6.5 7.5 1.1 9.3 3.2 1.7 2 0 0 2 2 2 0 Mitochondrial calcium uniporter Fungal_trans PF04082.18 OAP60116.1 - 2.8e-29 102.0 0.0 4.5e-29 101.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP60116.1 - 2.3e-05 24.4 12.3 5.8e-05 23.1 12.3 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UTP15_C PF09384.10 OAP60116.1 - 0.069 12.8 0.1 0.18 11.4 0.1 1.7 1 1 0 1 1 1 0 UTP15 C terminal Peptidase_S10 PF00450.22 OAP60117.1 - 2.6e-97 326.9 2.2 3.1e-97 326.7 2.2 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase DNA_pol_lambd_f PF10391.9 OAP60118.1 - 0.066 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda DUF3659 PF12396.8 OAP60119.1 - 3.9e-274 885.0 162.0 1.8e-23 82.2 0.5 14.4 14 0 0 14 14 14 13 Protein of unknown function (DUF3659) RPW8 PF05659.11 OAP60119.1 - 0.054 13.2 3.1 0.054 13.2 1.4 1.9 2 0 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 FCD PF07729.12 OAP60119.1 - 0.83 10.1 8.0 1.7 9.1 6.3 2.4 3 0 0 3 3 3 0 FCD domain Phage_fiber_C PF06820.12 OAP60119.1 - 1.6 9.1 10.7 1.5e+02 2.8 0.0 7.5 8 1 0 8 8 8 0 Putative prophage tail fibre C-terminus Acetyltransf_10 PF13673.7 OAP60120.1 - 0.0001 22.2 0.0 0.00017 21.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAP60120.1 - 0.0029 17.8 0.0 0.0049 17.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OAP60120.1 - 0.0037 17.7 0.0 0.006 17.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 OAP60120.1 - 0.011 15.8 0.0 0.018 15.1 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain NMO PF03060.15 OAP60121.1 - 9.4e-56 189.6 4.5 1.3e-55 189.1 4.5 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 OAP60121.1 - 1.6e-09 37.2 3.3 3.5e-09 36.1 3.3 1.5 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 OAP60121.1 - 9.4e-08 31.4 3.0 1.7e-07 30.6 3.0 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 OAP60121.1 - 0.0025 17.0 1.4 0.0047 16.1 1.4 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase PEP_hydrolase PF09370.10 OAP60121.1 - 0.084 12.1 0.1 0.19 11.0 0.1 1.6 1 0 0 1 1 1 0 Phosphoenolpyruvate hydrolase-like DHO_dh PF01180.21 OAP60121.1 - 0.13 11.5 0.2 0.23 10.6 0.2 1.4 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase NmrA PF05368.13 OAP60122.1 - 3.3e-07 30.1 0.0 5.8e-07 29.3 0.0 1.4 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAP60122.1 - 0.073 13.0 0.1 0.56 10.1 0.1 2.3 1 1 0 1 1 1 0 NAD(P)H-binding Epimerase PF01370.21 OAP60122.1 - 0.2 11.1 0.4 1.1 8.7 0.1 1.9 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family AAA PF00004.29 OAP60123.1 - 2.7e-48 163.8 1.2 3.6e-41 140.7 0.0 3.6 3 1 0 4 4 3 3 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OAP60123.1 - 4.8e-16 58.3 1.7 4e-10 39.3 0.5 3.2 3 0 0 3 3 2 2 AAA+ lid domain AAA_16 PF13191.6 OAP60123.1 - 3.6e-09 37.2 0.4 0.011 16.2 0.0 3.7 2 2 0 3 3 3 2 AAA ATPase domain AAA_5 PF07728.14 OAP60123.1 - 3.7e-07 30.2 0.5 0.00096 19.2 0.1 3.1 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) DUF815 PF05673.13 OAP60123.1 - 2.9e-06 26.6 0.0 0.0055 15.9 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_28 PF13521.6 OAP60123.1 - 8.3e-06 26.1 0.0 0.067 13.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain Rad17 PF03215.15 OAP60123.1 - 4.5e-05 23.4 0.0 0.0027 17.7 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain RuvB_N PF05496.12 OAP60123.1 - 0.00012 21.9 0.0 0.0027 17.4 0.0 2.7 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 OAP60123.1 - 0.00012 22.3 0.0 1.9 8.8 0.0 3.6 2 1 1 3 3 3 1 AAA domain RNA_helicase PF00910.22 OAP60123.1 - 0.00032 21.1 0.0 0.68 10.3 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_2 PF07724.14 OAP60123.1 - 0.0012 19.0 0.0 0.0028 17.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 OAP60123.1 - 0.0013 18.0 0.0 0.039 13.1 0.0 2.2 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_7 PF12775.7 OAP60123.1 - 0.0023 17.5 0.0 1 8.9 0.0 2.6 3 0 0 3 3 3 1 P-loop containing dynein motor region CDC48_N PF02359.18 OAP60123.1 - 0.0023 18.1 0.0 0.0071 16.5 0.0 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_33 PF13671.6 OAP60123.1 - 0.0033 17.6 0.0 0.74 10.0 0.0 2.9 3 0 0 3 3 2 1 AAA domain TsaE PF02367.17 OAP60123.1 - 0.0039 17.2 0.0 0.75 9.8 0.0 2.3 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 OAP60123.1 - 0.0044 16.6 1.0 3.8 7.0 0.0 3.0 2 1 1 3 3 3 1 AAA domain IstB_IS21 PF01695.17 OAP60123.1 - 0.0053 16.5 0.0 1 9.1 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein ATPase_2 PF01637.18 OAP60123.1 - 0.0063 16.4 0.0 5.8 6.8 0.0 3.1 2 1 1 3 3 3 1 ATPase domain predominantly from Archaea AAA_3 PF07726.11 OAP60123.1 - 0.0063 16.4 0.1 0.039 13.8 0.0 2.4 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 OAP60123.1 - 0.013 16.0 0.0 11 6.5 0.0 2.7 2 0 0 2 2 2 0 ABC transporter AAA_29 PF13555.6 OAP60123.1 - 0.014 15.1 0.0 0.41 10.4 0.0 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain Sigma54_activ_2 PF14532.6 OAP60123.1 - 0.017 15.2 0.0 0.29 11.2 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain NACHT PF05729.12 OAP60123.1 - 0.018 15.0 0.2 12 5.8 0.0 3.3 3 1 0 3 3 3 0 NACHT domain Adeno_IVa2 PF02456.15 OAP60123.1 - 0.027 13.3 0.0 4.1 6.1 0.0 2.6 2 1 0 2 2 2 0 Adenovirus IVa2 protein Vps4_C PF09336.10 OAP60123.1 - 0.033 14.2 0.1 14 5.8 0.0 2.6 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain Mg_chelatase PF01078.21 OAP60123.1 - 0.037 13.4 0.1 1.4 8.3 0.0 2.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 OAP60123.1 - 0.066 13.2 0.0 1.4 8.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 OAP60123.1 - 0.15 11.7 0.0 6.7 6.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain zinc_ribbon_10 PF10058.9 OAP60124.1 - 8.1e-19 67.1 0.1 1.3e-18 66.4 0.1 1.4 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein DUF4271 PF14093.6 OAP60124.1 - 0.032 14.1 0.1 0.045 13.7 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4271) Ima1_N PF09779.9 OAP60124.1 - 0.095 13.6 0.5 0.095 13.6 0.5 2.3 2 1 0 2 2 2 0 Ima1 N-terminal domain Rubredoxin_2 PF18073.1 OAP60124.1 - 8.6 6.2 9.2 0.8 9.5 4.0 1.9 2 0 0 2 2 2 0 Rubredoxin metal binding domain ADH_zinc_N PF00107.26 OAP60125.1 - 2.5e-15 56.6 0.0 4.9e-15 55.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAP60125.1 - 0.0012 19.9 0.0 0.0022 19.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAP60125.1 - 0.0021 17.9 0.0 0.0047 16.8 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Pyridoxal_deC PF00282.19 OAP60126.1 - 1.1e-108 363.3 0.0 1.4e-108 363.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain SMC_Nse1 PF07574.13 OAP60127.1 - 1.3e-60 204.7 0.2 2.1e-60 203.9 0.2 1.4 1 0 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex Glyco_hydro_65N PF03636.15 OAP60127.1 - 9.4e-34 117.0 0.1 1.6e-33 116.3 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_65m PF03632.15 OAP60127.1 - 2.9e-25 89.0 2.1 8.4e-20 71.0 0.2 2.2 1 1 1 2 2 2 2 Glycosyl hydrolase family 65 central catalytic domain F5_F8_type_C PF00754.25 OAP60127.1 - 0.0041 17.2 0.0 0.017 15.2 0.0 2.0 1 0 0 1 1 1 1 F5/8 type C domain CBFD_NFYB_HMF PF00808.23 OAP60128.1 - 7.2e-11 42.2 0.1 3.5e-08 33.6 0.0 2.2 2 0 0 2 2 2 2 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Rrf2 PF02082.20 OAP60128.1 - 0.12 12.7 0.0 0.32 11.4 0.0 1.7 1 1 1 2 2 2 0 Transcriptional regulator adh_short PF00106.25 OAP60129.1 - 5.6e-35 120.6 0.0 6.6e-35 120.4 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP60129.1 - 2.9e-21 76.1 0.0 3.4e-21 75.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP60129.1 - 1e-09 38.6 0.6 1.2e-07 31.8 0.1 2.1 1 1 1 2 2 2 2 KR domain DUF1776 PF08643.10 OAP60129.1 - 0.0027 17.2 0.0 0.0037 16.7 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Polysacc_synt_2 PF02719.15 OAP60129.1 - 0.074 12.2 0.1 0.2 10.8 0.1 1.6 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein FAA_hydrolase PF01557.18 OAP60130.1 - 2.4e-61 207.2 0.0 3.2e-61 206.8 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family p450 PF00067.22 OAP60131.1 - 8.9e-73 245.6 0.0 1.1e-72 245.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fasciclin PF02469.22 OAP60132.1 - 6e-22 78.2 0.0 7.5e-10 39.1 0.0 2.3 2 0 0 2 2 2 2 Fasciclin domain SKG6 PF08693.10 OAP60132.1 - 0.027 13.9 0.4 0.068 12.6 0.4 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain VSP PF03302.13 OAP60132.1 - 0.33 9.8 1.4 0.49 9.2 1.4 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein adh_short_C2 PF13561.6 OAP60133.1 - 5.1e-60 202.9 2.8 8.5e-60 202.2 2.8 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP60133.1 - 1.9e-47 161.2 0.3 2.8e-47 160.7 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAP60133.1 - 8.5e-12 45.3 1.5 4.6e-11 42.9 1.5 1.9 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OAP60133.1 - 3e-06 26.6 0.0 4.7e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 OAP60133.1 - 0.008 15.7 0.9 0.018 14.5 0.9 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family E1-E2_ATPase PF00122.20 OAP60134.1 - 1.6e-45 154.9 4.8 1.6e-45 154.9 4.8 2.7 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 OAP60134.1 - 4.8e-17 62.9 0.0 1.9e-16 61.0 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 OAP60134.1 - 2e-08 33.8 0.0 4.2e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 OAP60134.1 - 0.00046 20.2 0.0 0.00095 19.2 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 OAP60134.1 - 0.0026 17.5 0.3 0.0064 16.3 0.1 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase O-antigen_lig PF13425.6 OAP60134.1 - 0.14 11.0 5.1 0.31 9.8 5.1 1.5 1 0 0 1 1 1 0 O-antigen ligase like membrane protein CTD_bind PF04818.13 OAP60135.1 - 6.7e-09 36.4 0.0 1.4e-08 35.5 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase II-binding domain. RRM_1 PF00076.22 OAP60135.1 - 5.7e-07 29.3 0.0 9.7e-07 28.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TFIIA PF03153.13 OAP60135.1 - 5.4 6.9 5.5 7.2 6.5 5.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Citrate_synt PF00285.21 OAP60136.1 - 1.9e-100 336.4 0.0 2.4e-100 336.1 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Eclosion PF04736.12 OAP60136.1 - 0.11 12.3 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Eclosion hormone Mito_carr PF00153.27 OAP60137.1 - 2.3e-27 94.8 4.9 4.6e-11 42.5 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein PALP PF00291.25 OAP60139.1 - 6.5e-69 232.6 0.2 7.9e-69 232.3 0.2 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DAHP_snth_FXD PF18152.1 OAP60139.1 - 0.1 12.5 0.0 0.24 11.2 0.0 1.6 1 0 0 1 1 1 0 DAHP synthase ferredoxin-like domain ZnuA PF01297.17 OAP60139.1 - 0.18 11.2 0.3 0.8 9.1 0.8 1.5 1 1 0 1 1 1 0 Zinc-uptake complex component A periplasmic Amidohydro_1 PF01979.20 OAP60140.1 - 5.1e-25 88.5 0.0 1.3e-24 87.2 0.0 1.7 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 OAP60140.1 - 8.8e-20 71.6 0.0 1.8e-09 37.6 0.0 3.1 3 0 0 3 3 3 2 Amidohydrolase family Amidohydro_2 PF04909.14 OAP60140.1 - 0.0083 15.9 0.0 0.016 15.0 0.0 1.6 1 1 0 1 1 1 1 Amidohydrolase Urease_alpha PF00449.20 OAP60140.1 - 0.064 13.6 1.0 0.092 13.1 0.2 1.7 2 0 0 2 2 2 0 Urease alpha-subunit, N-terminal domain tRNA-synt_1c PF00749.21 OAP60141.1 - 2.2e-101 338.9 0.0 3.2e-101 338.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 OAP60141.1 - 4.3e-32 111.4 0.8 1.1e-31 110.0 0.8 1.7 1 1 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain Ribosomal_L1 PF00687.21 OAP60142.1 - 5.7e-27 94.8 0.0 9.5e-27 94.1 0.0 1.4 1 1 0 1 1 1 1 Ribosomal protein L1p/L10e family SR-25 PF10500.9 OAP60142.1 - 0.014 15.0 0.3 0.024 14.2 0.3 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein COG2 PF06148.11 OAP60143.1 - 8.7e-32 110.0 1.5 8.7e-32 110.0 1.5 1.6 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.11 OAP60143.1 - 3e-07 30.4 1.4 2.2e-06 27.7 0.1 2.5 2 0 0 2 2 2 1 Vps51/Vps67 COG5 PF10392.9 OAP60143.1 - 0.00017 21.8 0.8 0.00017 21.8 0.8 2.1 2 0 0 2 2 2 1 Golgi transport complex subunit 5 Sec8_exocyst PF04048.14 OAP60143.1 - 0.029 14.2 0.2 0.053 13.4 0.2 1.4 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain Zw10 PF06248.13 OAP60143.1 - 0.059 11.9 2.6 0.033 12.8 0.8 1.4 2 0 0 2 2 2 0 Centromere/kinetochore Zw10 NPV_P10 PF05531.12 OAP60143.1 - 0.069 13.6 6.0 0.78 10.2 0.2 3.2 3 2 0 3 3 3 0 Nucleopolyhedrovirus P10 protein kleA_kleC PF17383.2 OAP60143.1 - 0.078 13.3 0.5 0.24 11.7 0.5 1.8 1 0 0 1 1 1 0 Uncharacterized KorC regulated protein A VWA_2 PF13519.6 OAP60143.1 - 0.1 13.3 0.1 0.31 11.7 0.1 1.8 1 1 0 1 1 1 0 von Willebrand factor type A domain DUF16 PF01519.16 OAP60143.1 - 0.11 13.0 5.0 0.079 13.5 1.9 2.3 2 1 0 2 2 2 0 Protein of unknown function DUF16 TSC22 PF01166.18 OAP60143.1 - 0.44 10.9 6.3 0.12 12.7 1.5 2.4 2 0 0 2 2 2 0 TSC-22/dip/bun family SGS PF05002.15 OAP60144.1 - 4.1e-25 87.7 10.4 3.3e-24 84.8 10.4 2.4 1 1 0 1 1 1 1 SGS domain CS PF04969.16 OAP60144.1 - 2.9e-14 53.8 0.0 6.7e-14 52.7 0.0 1.6 1 0 0 1 1 1 1 CS domain TPR_16 PF13432.6 OAP60144.1 - 0.0013 19.4 3.5 0.025 15.2 1.6 2.8 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 OAP60144.1 - 0.0045 17.5 1.2 2.7 8.6 0.8 2.9 2 1 0 2 2 2 2 Tetratricopeptide repeat DUF2057 PF09829.9 OAP60144.1 - 0.03 14.5 7.6 0.13 12.4 2.4 2.9 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2057) TPR_2 PF07719.17 OAP60144.1 - 0.2 11.8 3.1 2.3 8.6 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 OAP60144.1 - 6.2 7.9 6.0 12 7.0 0.2 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat 7tm_3 PF00003.22 OAP60145.1 - 0.026 14.3 10.5 0.042 13.6 10.5 1.2 1 0 0 1 1 1 0 7 transmembrane sweet-taste receptor of 3 GCPR DUF4234 PF14018.6 OAP60145.1 - 0.11 12.6 0.1 0.29 11.3 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4234) DUF2569 PF10754.9 OAP60145.1 - 4.5 7.7 8.0 6.7 7.2 5.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2569) RdRP PF05183.12 OAP60146.1 - 2.6e-110 369.8 0.0 3.6e-110 369.4 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase RapH_N PF18801.1 OAP60146.1 - 0.087 12.9 0.1 0.27 11.4 0.1 1.8 1 0 0 1 1 1 0 response regulator aspartate phosphatase H, N terminal Metallophos PF00149.28 OAP60147.1 - 7.3e-36 124.6 0.1 1.4e-35 123.7 0.1 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF1647 PF07801.11 OAP60147.1 - 0.088 12.5 0.6 2 8.1 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1647) p450 PF00067.22 OAP60148.1 - 7.3e-70 236.0 0.0 1.1e-69 235.4 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 TAL_FSA PF00923.19 OAP60149.1 - 2.2e-65 220.9 0.1 2.7e-65 220.6 0.1 1.1 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase Zn_clus PF00172.18 OAP60150.1 - 0.0035 17.4 0.9 0.0035 17.4 0.9 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Creb_binding PF09030.10 OAP60150.1 - 0.017 15.8 1.8 0.029 15.0 0.1 2.2 2 0 0 2 2 2 0 Creb binding DUF1192 PF06698.11 OAP60150.1 - 0.31 11.1 3.9 0.37 10.9 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) Aldedh PF00171.22 OAP60151.1 - 3.9e-169 563.0 0.1 4.4e-169 562.9 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Sugar_tr PF00083.24 OAP60152.1 - 1.3e-118 396.7 18.3 1.5e-118 396.5 18.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP60152.1 - 2.1e-28 99.3 20.1 2.1e-28 99.3 20.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Cyclase PF04199.13 OAP60153.1 - 8.1e-13 48.8 0.1 1.1e-12 48.4 0.1 1.2 1 0 0 1 1 1 1 Putative cyclase 2OG-FeII_Oxy PF03171.20 OAP60157.1 - 1.3e-15 57.7 0.1 5.8e-15 55.6 0.1 2.0 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 OAP60157.1 - 4.3e-08 33.9 0.1 2e-06 28.5 0.1 2.2 1 1 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal GAT PF03127.14 OAP60157.1 - 0.18 12.1 0.0 0.38 11.1 0.0 1.4 1 0 0 1 1 1 0 GAT domain DAO PF01266.24 OAP60158.1 - 5e-43 148.0 0.9 6.1e-43 147.8 0.9 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 OAP60158.1 - 3.3e-05 24.4 0.0 0.2 12.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAP60158.1 - 0.0041 16.4 0.0 1.9 7.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAP60158.1 - 0.0064 16.7 0.3 0.019 15.2 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 OAP60158.1 - 0.22 10.2 0.0 0.42 9.3 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein MCRA PF06100.11 OAP60158.1 - 0.39 9.4 0.5 0.69 8.6 0.5 1.3 1 0 0 1 1 1 0 MCRA family His_Phos_1 PF00300.22 OAP60159.1 - 1.2e-05 25.1 0.0 2.9e-05 23.8 0.0 1.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF3245 PF11595.8 OAP60161.1 - 0.00017 22.1 4.9 0.00017 22.1 4.9 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF3245) FAM176 PF14851.6 OAP60161.1 - 1.7 8.3 3.3 23 4.7 0.3 2.4 2 0 0 2 2 2 0 FAM176 family HSF_DNA-bind PF00447.17 OAP60162.1 - 2.8e-30 104.8 2.1 4.5e-30 104.1 2.1 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding CytoC_RC PF02276.18 OAP60162.1 - 0.069 12.5 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Photosynthetic reaction centre cytochrome C subunit Peptidase_C97 PF05903.14 OAP60162.1 - 0.073 12.9 0.0 7.6 6.4 0.0 2.2 2 0 0 2 2 2 0 PPPDE putative peptidase domain Ets PF00178.22 OAP60162.1 - 0.16 12.4 0.1 0.31 11.5 0.1 1.4 1 0 0 1 1 1 0 Ets-domain Bystin PF05291.11 OAP60163.1 - 1.9e-127 424.6 0.0 2.4e-127 424.2 0.0 1.1 1 0 0 1 1 1 1 Bystin HET PF06985.11 OAP60164.1 - 1.9e-32 112.7 1.5 3e-32 112.0 1.5 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PAP1 PF08601.10 OAP60164.1 - 0.33 10.6 5.7 0.54 9.9 5.7 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 PBP_N PF17093.5 OAP60164.1 - 3.6 7.9 6.3 10 6.4 6.3 1.7 1 0 0 1 1 1 0 Penicillin-binding protein N-terminus Amidase PF01425.21 OAP60165.1 - 1.1e-110 370.7 0.9 2.5e-66 224.5 2.6 2.1 1 1 0 2 2 2 2 Amidase TatD_DNase PF01026.21 OAP60166.1 - 1.8e-08 34.1 0.0 1.2e-07 31.3 0.0 2.0 2 0 0 2 2 2 1 TatD related DNase Fungal_trans PF04082.18 OAP60166.1 - 4.8e-06 25.8 0.0 7.8e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain HAD_2 PF13419.6 OAP60167.1 - 1.9e-10 41.1 0.0 3.2e-10 40.4 0.0 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OAP60167.1 - 0.0015 18.9 0.0 0.072 13.4 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase ATP-grasp_2 PF08442.10 OAP60168.1 - 1.3e-79 266.4 0.3 2.5e-79 265.6 0.3 1.4 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 OAP60168.1 - 4.1e-23 81.9 0.3 7.5e-23 81.0 0.3 1.5 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 OAP60168.1 - 3.6e-09 36.4 0.5 1.2e-08 34.7 0.2 1.9 2 0 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.19 OAP60168.1 - 0.01 15.6 0.3 0.033 13.9 0.0 2.0 2 1 0 2 2 2 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain VID27_N PF17748.1 OAP60168.1 - 0.047 13.5 0.6 0.083 12.7 0.6 1.3 1 0 0 1 1 1 0 VID27 N-terminal region DAO_C PF16901.5 OAP60168.1 - 0.15 11.9 0.0 4 7.3 0.0 2.5 3 0 0 3 3 3 0 C-terminal domain of alpha-glycerophosphate oxidase zf-His_Me_endon PF05551.11 OAP60169.1 - 1.1e-11 45.0 2.1 1.1e-11 45.0 2.1 1.8 2 0 0 2 2 2 1 Zinc-binding loop region of homing endonuclease Myb_DNA-bind_2 PF08914.11 OAP60170.1 - 2.3e-10 40.5 0.0 5.8e-10 39.2 0.0 1.7 1 0 0 1 1 1 1 Rap1 Myb domain DUF4191 PF13829.6 OAP60170.1 - 0.12 11.7 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) Kinesin PF00225.23 OAP60171.1 - 4.6e-13 48.8 0.0 1.4e-07 30.8 0.0 2.2 2 0 0 2 2 2 2 Kinesin motor domain HALZ PF02183.18 OAP60171.1 - 0.0039 17.4 1.9 1.6 9.0 0.3 2.6 2 0 0 2 2 2 2 Homeobox associated leucine zipper DivIC PF04977.15 OAP60171.1 - 0.038 13.8 0.5 0.038 13.8 0.5 2.8 3 0 0 3 3 3 0 Septum formation initiator IHHNV_capsid PF16530.5 OAP60171.1 - 0.058 12.5 0.0 0.097 11.8 0.0 1.2 1 0 0 1 1 1 0 Infectious hypodermal and haematopoietic necrosis virus, capsid DUF1318 PF07027.12 OAP60171.1 - 0.091 13.2 0.0 0.2 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1318) UPF0242 PF06785.11 OAP60171.1 - 0.12 12.4 0.4 0.42 10.7 0.4 1.9 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus ATG16 PF08614.11 OAP60171.1 - 0.12 12.5 13.1 0.047 13.9 7.6 2.4 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) KASH_CCD PF14662.6 OAP60171.1 - 0.14 11.9 4.5 0.26 11.1 4.5 1.4 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH CCDC154 PF15450.6 OAP60171.1 - 0.24 9.9 8.7 0.36 9.3 8.7 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 154 YabA PF06156.13 OAP60171.1 - 0.31 11.7 2.0 4.7 7.9 2.0 2.4 1 1 0 1 1 1 0 Initiation control protein YabA Cep57_CLD_2 PF14197.6 OAP60171.1 - 0.4 10.8 13.6 1.6 8.9 1.0 3.0 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 Jnk-SapK_ap_N PF09744.9 OAP60171.1 - 0.46 10.7 7.2 0.82 9.9 6.6 1.7 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 Fez1 PF06818.15 OAP60171.1 - 2.2 8.7 6.2 4.5 7.7 6.2 1.5 1 0 0 1 1 1 0 Fez1 Spc7 PF08317.11 OAP60171.1 - 3.1 6.6 5.0 5.4 5.8 5.0 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF3450 PF11932.8 OAP60171.1 - 5.8 6.1 8.8 2 7.7 1.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) SNF2_N PF00176.23 OAP60172.1 - 1e-15 57.4 0.0 1.6e-15 56.7 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OAP60172.1 - 1.1e-06 28.9 0.0 2.5e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4193 PF13834.6 OAP60176.1 - 0.00079 19.9 0.4 0.0057 17.1 0.1 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF4193) zf-UDP PF14569.6 OAP60176.1 - 0.39 10.9 2.8 4.8 7.4 2.8 2.4 1 1 0 1 1 1 0 Zinc-binding RING-finger FYVE PF01363.21 OAP60176.1 - 0.43 10.8 8.9 0.089 12.9 1.0 2.4 1 1 0 2 2 2 0 FYVE zinc finger ADD_ATRX PF17981.1 OAP60176.1 - 1.2 9.1 4.0 0.97 9.4 1.6 2.0 2 0 0 2 2 2 0 Cysteine Rich ADD domain zf-C3HC4 PF00097.25 OAP60176.1 - 2.5 8.1 5.4 0.99 9.3 0.9 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Zn_clus PF00172.18 OAP60177.1 - 3.2 7.9 7.9 7.1 6.8 7.9 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain SNF2_N PF00176.23 OAP60180.1 - 3.7e-08 32.5 0.0 6.9e-08 31.6 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OAP60180.1 - 0.0038 17.5 0.0 0.0074 16.6 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SLAC1 PF03595.17 OAP60189.1 - 1.4e-76 257.9 56.8 1.6e-76 257.7 56.8 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel POPLD PF08170.12 OAP60189.1 - 1.9 8.9 4.9 0.83 10.0 1.4 2.1 2 0 0 2 2 2 0 POPLD (NUC188) domain Pro_CA PF00484.19 OAP60190.1 - 4.9e-15 56.2 0.0 1e-14 55.1 0.0 1.5 1 1 0 1 1 1 1 Carbonic anhydrase GCIP PF13324.6 OAP60191.1 - 2.2e-23 83.2 0.6 3.2e-23 82.7 0.6 1.1 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting Sigma70_ner PF04546.13 OAP60191.1 - 0.0064 16.4 0.6 0.01 15.8 0.6 1.2 1 0 0 1 1 1 1 Sigma-70, non-essential region PMC2NT PF08066.12 OAP60191.1 - 0.055 14.2 0.9 10 6.9 0.0 2.7 2 1 1 3 3 3 0 PMC2NT (NUC016) domain Lactamase_B PF00753.27 OAP60192.1 - 1.5e-10 41.5 0.6 2.4e-10 40.7 0.6 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OAP60192.1 - 0.002 17.7 0.5 0.0031 17.0 0.5 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain MFS_1 PF07690.16 OAP60193.1 - 1.8e-36 125.8 22.8 2.6e-36 125.3 22.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily p450 PF00067.22 OAP60194.1 - 4.7e-60 203.7 0.0 5.5e-60 203.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 GST_N_3 PF13417.6 OAP60195.1 - 1.3e-11 44.8 0.0 2.3e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OAP60195.1 - 2.4e-10 40.6 0.1 8e-10 38.9 0.0 1.9 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 OAP60195.1 - 2.2e-07 31.0 0.0 1.5e-06 28.3 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 OAP60195.1 - 2.8e-07 30.8 0.0 6.5e-07 29.6 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAP60195.1 - 1.3e-05 25.1 0.5 0.0042 17.1 0.0 2.7 3 0 0 3 3 3 2 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OAP60195.1 - 1.6e-05 25.0 0.0 3.9e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 OAP60195.1 - 0.00027 21.1 0.0 0.00054 20.1 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin NMT1 PF09084.11 OAP60196.1 - 0.00022 21.3 0.0 0.0088 16.0 0.0 2.3 2 0 0 2 2 2 2 NMT1/THI5 like GMC_oxred_N PF00732.19 OAP60197.1 - 2.1e-45 155.3 0.0 3.3e-45 154.7 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAP60197.1 - 1.7e-31 109.7 0.0 2.6e-31 109.1 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 OAP60197.1 - 0.00014 21.6 0.1 0.007 16.0 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAP60197.1 - 0.0028 17.8 0.3 0.0081 16.4 0.1 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAP60197.1 - 0.011 15.0 0.0 0.063 12.5 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OAP60197.1 - 0.016 14.3 0.1 0.032 13.3 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 OAP60197.1 - 0.11 12.4 0.4 0.26 11.3 0.1 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding Trp_halogenase PF04820.14 OAP60197.1 - 0.17 10.7 0.1 0.24 10.2 0.1 1.1 1 0 0 1 1 1 0 Tryptophan halogenase Fungal_trans PF04082.18 OAP60198.1 - 3.6e-31 108.2 0.1 5.3e-31 107.6 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP60198.1 - 6.3e-10 39.0 6.5 1.1e-09 38.3 6.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 OAP60198.1 - 0.0064 15.3 0.5 0.063 12.1 0.5 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Amidohydro_2 PF04909.14 OAP60199.1 - 1.6e-41 143.0 0.3 1.9e-41 142.7 0.3 1.1 1 0 0 1 1 1 1 Amidohydrolase DED PF01335.21 OAP60199.1 - 0.12 12.7 0.0 0.27 11.5 0.0 1.6 1 0 0 1 1 1 0 Death effector domain WASH_WAHD PF11945.8 OAP60199.1 - 0.29 10.6 0.1 0.42 10.1 0.1 1.1 1 0 0 1 1 1 0 WAHD domain of WASH complex Cupin_2 PF07883.11 OAP60200.1 - 2.4e-20 72.0 1.3 2.9e-18 65.4 0.3 2.5 2 1 0 2 2 2 2 Cupin domain AraC_binding PF02311.19 OAP60200.1 - 3.3e-05 23.8 0.2 6.5e-05 22.8 0.2 1.5 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_3 PF05899.12 OAP60200.1 - 8.8e-05 22.1 0.1 0.071 12.8 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) Auxin_BP PF02041.16 OAP60200.1 - 9.9e-05 22.1 0.0 0.057 13.1 0.0 2.3 2 0 0 2 2 2 2 Auxin binding protein DMSP_lyase PF16867.5 OAP60200.1 - 0.0097 15.6 0.2 0.026 14.2 0.2 1.7 1 0 0 1 1 1 1 Dimethlysulfonioproprionate lyase Cupin_1 PF00190.22 OAP60200.1 - 0.029 14.0 0.0 6.6 6.3 0.0 2.3 2 0 0 2 2 2 0 Cupin FAD_binding_3 PF01494.19 OAP60201.1 - 2.8e-26 92.6 0.0 3.5e-26 92.3 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 OAP60201.1 - 2.8e-11 43.2 0.1 4.4e-05 22.9 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAP60201.1 - 1.8e-07 31.3 0.4 5.2e-07 29.8 0.4 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 OAP60201.1 - 3.2e-07 29.6 2.5 0.0024 16.8 0.0 2.9 1 1 0 2 2 2 2 Tryptophan halogenase DAO PF01266.24 OAP60201.1 - 4.6e-07 29.7 7.0 0.00021 21.0 2.8 2.9 1 1 2 3 3 3 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 OAP60201.1 - 7.2e-07 29.7 0.4 0.0017 18.9 0.3 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAP60201.1 - 8.7e-07 28.0 0.5 0.00074 18.3 0.6 2.1 2 0 0 2 2 2 2 HI0933-like protein FAD_oxidored PF12831.7 OAP60201.1 - 1.1e-05 24.9 0.0 1.7e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OAP60201.1 - 2.6e-05 23.5 2.8 4e-05 22.9 2.0 1.6 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 OAP60201.1 - 4.1e-05 22.8 0.1 0.00013 21.1 0.1 1.8 1 1 0 1 1 1 1 Lycopene cyclase protein Amino_oxidase PF01593.24 OAP60201.1 - 5.2e-05 22.7 0.1 0.091 12.0 0.1 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase GIDA PF01134.22 OAP60201.1 - 0.0007 18.8 0.7 0.0011 18.1 0.7 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 OAP60201.1 - 0.0013 18.1 0.0 0.0024 17.2 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 OAP60201.1 - 0.0019 17.5 0.7 0.0046 16.2 0.7 1.6 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 OAP60201.1 - 0.019 14.2 0.7 0.043 13.1 0.7 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 OAP60201.1 - 0.08 12.0 0.0 0.13 11.3 0.0 1.4 1 1 0 1 1 1 0 Squalene epoxidase NAD_binding_9 PF13454.6 OAP60201.1 - 0.19 11.7 4.4 1.1 9.3 2.1 2.8 2 1 0 2 2 2 0 FAD-NAD(P)-binding 3HCDH_N PF02737.18 OAP60201.1 - 0.36 10.7 1.1 0.63 9.9 1.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sugar_tr PF00083.24 OAP60202.1 - 1.4e-94 317.6 24.2 1.6e-94 317.3 24.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP60202.1 - 1.6e-24 86.5 23.6 1.6e-24 86.5 23.6 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF2070 PF09843.9 OAP60202.1 - 3.7 5.7 8.0 7.2 4.8 8.0 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) adh_short_C2 PF13561.6 OAP60203.1 - 1.2e-48 165.7 0.1 6.7e-47 160.0 0.0 2.5 2 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP60203.1 - 5.5e-37 127.1 0.0 6.9e-36 123.5 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAP60203.1 - 4.7e-10 39.7 0.0 2e-09 37.6 0.0 2.2 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 OAP60203.1 - 0.031 13.8 0.0 0.044 13.3 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Aldedh PF00171.22 OAP60204.1 - 8.3e-166 552.1 0.2 9.5e-166 551.9 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Cyclase PF04199.13 OAP60205.1 - 1.4e-13 51.2 0.0 2e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 Putative cyclase Glyoxalase PF00903.25 OAP60206.1 - 4.1e-11 43.2 0.0 6e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 OAP60206.1 - 9.2e-09 35.6 0.0 1.2e-08 35.2 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 OAP60206.1 - 6.3e-08 33.4 0.0 1.9e-07 31.9 0.0 1.7 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_3 PF13468.6 OAP60206.1 - 7.3e-05 22.9 0.0 0.00025 21.2 0.0 1.7 1 1 0 1 1 1 1 Glyoxalase-like domain Aldo_ket_red PF00248.21 OAP60207.1 - 4.3e-45 154.1 0.0 1.4e-44 152.5 0.0 1.7 1 1 0 1 1 1 1 Aldo/keto reductase family Fungal_trans PF04082.18 OAP60208.1 - 7.1e-16 58.0 0.2 1.1e-15 57.4 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP60208.1 - 8.7e-05 22.6 14.3 0.00018 21.6 14.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_N PF08240.12 OAP60209.1 - 4.6e-28 97.3 0.4 1e-27 96.2 0.3 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAP60209.1 - 5.1e-26 91.2 0.0 7.9e-26 90.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 OAP60209.1 - 8.2e-08 32.0 0.1 1.3e-07 31.4 0.1 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 OAP60209.1 - 3.3e-05 25.0 0.0 8.1e-05 23.7 0.0 1.7 1 1 1 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 OAP60209.1 - 0.0047 16.3 0.0 0.0086 15.4 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 OAP60209.1 - 0.16 12.1 0.0 0.29 11.2 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ADH_N PF08240.12 OAP60210.1 - 1.8e-28 98.6 1.1 3.5e-28 97.7 0.0 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAP60210.1 - 3.3e-18 65.9 0.9 5.7e-18 65.1 0.9 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAP60210.1 - 2.2e-07 32.0 0.0 5.3e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 OAP60210.1 - 2.5e-06 27.1 2.3 0.00079 19.0 2.3 2.5 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus Cas_csx3 PF09620.10 OAP60210.1 - 0.018 14.9 0.0 0.05 13.5 0.0 1.7 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_csx3) HI0933_like PF03486.14 OAP60210.1 - 0.062 12.0 1.6 0.089 11.5 1.6 1.2 1 0 0 1 1 1 0 HI0933-like protein ThiF PF00899.21 OAP60210.1 - 0.14 11.5 0.7 0.3 10.4 0.7 1.5 1 0 0 1 1 1 0 ThiF family UDPG_MGDP_dh_N PF03721.14 OAP60210.1 - 0.18 11.4 0.5 0.63 9.6 0.2 2.0 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FMO-like PF00743.19 OAP60211.1 - 9.1e-13 47.5 0.0 2.3e-12 46.1 0.0 1.6 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 OAP60211.1 - 2.9e-10 39.9 0.0 9.9e-09 34.8 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAP60211.1 - 4.3e-10 39.3 0.2 1.4e-07 31.0 0.1 3.0 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 OAP60211.1 - 2e-09 37.1 0.0 8.1e-09 35.2 0.0 2.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAP60211.1 - 2.8e-08 33.9 0.0 7.3e-08 32.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAP60211.1 - 0.00027 20.6 0.5 0.062 12.9 0.1 2.7 2 1 1 3 3 3 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 OAP60211.1 - 0.022 13.8 0.0 0.034 13.2 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 OAP60211.1 - 0.046 13.7 0.1 0.69 9.9 0.0 3.0 4 0 0 4 4 4 0 FAD-NAD(P)-binding Transketolase_N PF00456.21 OAP60212.1 - 3.8e-101 338.4 0.1 5.2e-101 338.0 0.1 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 OAP60212.1 - 1.4e-34 119.3 0.3 3.6e-34 118.0 0.3 1.6 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 OAP60212.1 - 4e-11 42.9 0.0 1.2e-10 41.3 0.0 1.8 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 OAP60212.1 - 1.5e-06 27.7 0.0 0.0049 16.1 0.0 2.3 2 0 0 2 2 2 2 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 OAP60212.1 - 6e-05 22.9 0.3 0.003 17.3 0.1 3.3 3 1 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.20 OAP60212.1 - 0.094 11.7 0.0 0.16 10.9 0.0 1.4 1 0 0 1 1 1 0 Dehydrogenase E1 component adh_short_C2 PF13561.6 OAP60213.1 - 4.8e-59 199.8 3.8 7.3e-59 199.2 3.8 1.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP60213.1 - 1.5e-45 155.1 1.4 1.9e-45 154.7 1.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAP60213.1 - 4.9e-08 33.1 1.7 1.9e-07 31.2 1.7 1.8 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 OAP60214.1 - 5e-11 42.5 0.2 6.5e-05 22.5 0.1 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 OAP60214.1 - 1.8e-07 31.3 0.3 3e-07 30.5 0.3 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 OAP60214.1 - 4.1e-06 27.2 0.2 2.5e-05 24.7 0.1 2.2 3 0 0 3 3 3 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 OAP60214.1 - 0.0031 16.5 0.0 0.094 11.7 0.0 2.0 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 OAP60214.1 - 0.0033 17.0 0.1 0.0048 16.5 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family GDP_Man_Dehyd PF16363.5 OAP60214.1 - 0.0098 15.3 0.2 0.039 13.3 0.0 2.0 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase Sacchrp_dh_NADP PF03435.18 OAP60214.1 - 0.012 15.8 0.0 0.036 14.3 0.0 1.8 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain RmlD_sub_bind PF04321.17 OAP60214.1 - 0.047 12.8 0.1 1.4 7.9 0.0 2.2 2 0 0 2 2 2 0 RmlD substrate binding domain DXP_reductoisom PF02670.16 OAP60214.1 - 0.073 13.8 0.0 0.16 12.7 0.0 1.5 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase DUF3426 PF11906.8 OAP60214.1 - 0.13 12.4 0.1 0.28 11.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3426) Abhydrolase_1 PF00561.20 OAP60215.1 - 4.9e-21 75.5 0.3 8.6e-20 71.5 0.3 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAP60215.1 - 1.8e-16 61.4 9.6 6.2e-16 59.7 9.6 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAP60215.1 - 1.7e-11 43.8 0.0 2.5e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 FAD_binding_4 PF01565.23 OAP60216.1 - 5.4e-23 81.3 2.7 1e-22 80.4 2.7 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 OAP60216.1 - 3.8e-13 49.3 0.0 1.1e-12 47.9 0.0 1.8 2 0 0 2 2 2 1 Berberine and berberine like RPS31 PF17067.5 OAP60216.1 - 0.048 13.8 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 Ribosomal protein S31e Cytokin-bind PF09265.10 OAP60216.1 - 0.17 11.2 0.2 0.27 10.6 0.2 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding Bul1_N PF04425.12 OAP60217.1 - 0.031 13.0 0.3 0.062 12.0 0.0 1.5 1 1 1 2 2 2 0 Bul1 N terminus Bul1_C PF04426.12 OAP60217.1 - 0.094 12.1 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Bul1 C terminus MMR_HSR1 PF01926.23 OAP60218.1 - 7.7e-10 38.9 0.0 2.4e-09 37.3 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AIG1 PF04548.16 OAP60218.1 - 1.5e-09 37.5 0.0 2.7e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 OAP60218.1 - 3.2e-05 24.1 1.3 0.071 13.2 0.2 3.0 2 1 1 3 3 3 2 Dynamin family RsgA_GTPase PF03193.16 OAP60218.1 - 0.0002 21.3 0.1 0.00057 19.8 0.1 1.8 1 1 0 1 1 1 1 RsgA GTPase Septin PF00735.18 OAP60218.1 - 0.00074 18.9 0.1 0.005 16.2 0.1 2.0 1 1 0 1 1 1 1 Septin IIGP PF05049.13 OAP60218.1 - 0.00096 18.3 0.0 0.0022 17.1 0.0 1.5 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) FtsK_SpoIIIE PF01580.18 OAP60218.1 - 0.0016 17.8 0.0 0.0037 16.6 0.0 1.6 1 0 0 1 1 1 1 FtsK/SpoIIIE family TsaE PF02367.17 OAP60218.1 - 0.0016 18.4 0.0 0.03 14.3 0.0 2.3 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE T2SSE PF00437.20 OAP60218.1 - 0.0045 16.1 0.0 0.0082 15.2 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 OAP60218.1 - 0.037 14.5 0.1 0.34 11.4 0.0 2.2 2 0 0 2 2 2 0 ABC transporter SRPRB PF09439.10 OAP60218.1 - 0.05 13.0 0.2 0.17 11.3 0.0 2.1 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 OAP60218.1 - 0.052 13.8 0.5 0.21 11.8 0.0 2.2 2 2 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 OAP60218.1 - 0.053 12.8 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin DUF87 PF01935.17 OAP60218.1 - 0.07 13.2 1.6 0.21 11.6 1.6 2.1 1 1 0 1 1 1 0 Helicase HerA, central domain AAA_16 PF13191.6 OAP60218.1 - 0.13 12.7 1.4 0.25 11.7 0.0 2.1 2 1 0 2 2 2 0 AAA ATPase domain AAA_19 PF13245.6 OAP60218.1 - 0.14 12.5 0.2 3.5 8.0 0.1 2.7 3 0 0 3 3 3 0 AAA domain Mhr1 PF12829.7 OAP60218.1 - 0.19 11.8 0.1 0.4 10.8 0.1 1.5 1 0 0 1 1 1 0 Transcriptional regulation of mitochondrial recombination PRP1_N PF06424.12 OAP60218.1 - 0.2 12.1 3.1 0.31 11.4 3.1 1.3 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal Macoilin PF09726.9 OAP60219.1 - 0.0018 17.0 0.6 0.0023 16.6 0.1 1.3 2 0 0 2 2 2 1 Macoilin family TMF_TATA_bd PF12325.8 OAP60219.1 - 0.047 13.9 0.8 0.8 9.9 0.1 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding HSP70 PF00012.20 OAP60220.1 - 7.9e-08 31.0 0.2 9.5e-07 27.4 0.1 2.0 2 0 0 2 2 2 2 Hsp70 protein Mif2_N PF15624.6 OAP60220.1 - 3.8 8.2 7.1 8.4 7.1 7.1 1.5 1 0 0 1 1 1 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Amidase PF01425.21 OAP60221.1 - 2e-81 274.3 0.0 2.9e-81 273.7 0.0 1.2 1 0 0 1 1 1 1 Amidase Amino_oxidase PF01593.24 OAP60222.1 - 3.2e-52 178.3 0.0 5.3e-52 177.6 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Ribonuc_L-PSP PF01042.21 OAP60222.1 - 6.4e-18 64.9 0.0 1.4e-17 63.8 0.0 1.5 2 0 0 2 2 1 1 Endoribonuclease L-PSP NAD_binding_8 PF13450.6 OAP60222.1 - 2.1e-12 47.1 0.1 4.4e-12 46.0 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 OAP60222.1 - 2.9e-07 29.9 1.6 4.8e-07 29.2 1.6 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAP60222.1 - 7.7e-07 29.0 1.2 6.1e-06 26.1 1.2 2.3 2 1 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 OAP60222.1 - 3.5e-06 26.4 0.1 5.6e-06 25.8 0.1 1.2 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 OAP60222.1 - 3.1e-05 23.4 0.0 4.9e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 OAP60222.1 - 5.1e-05 22.7 0.9 7.4e-05 22.1 0.9 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 OAP60222.1 - 0.0001 21.8 1.9 0.00017 21.1 1.9 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 OAP60222.1 - 0.00014 22.3 0.1 0.00035 21.1 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAP60222.1 - 0.00084 18.2 0.1 0.0027 16.5 0.3 1.6 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 OAP60222.1 - 0.0012 18.1 0.2 0.0016 17.6 0.2 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 OAP60222.1 - 0.0022 17.3 0.0 0.027 13.7 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OAP60222.1 - 0.0026 16.9 0.3 0.046 12.8 0.5 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 OAP60222.1 - 0.026 13.8 0.1 0.049 12.9 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DUF2231 PF09990.9 OAP60223.1 - 2.1e-08 34.6 0.1 3.5e-08 33.8 0.1 1.4 1 0 0 1 1 1 1 Predicted membrane protein (DUF2231) 2OG-FeII_Oxy PF03171.20 OAP60224.1 - 1.4e-06 28.8 0.0 2.6e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 OAP60224.1 - 0.00065 20.4 0.0 0.0012 19.5 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal ThiJ_like PF17124.5 OAP60225.1 - 9.1e-63 211.5 0.0 1.1e-62 211.2 0.0 1.0 1 0 0 1 1 1 1 ThiJ/PfpI family-like DJ-1_PfpI PF01965.24 OAP60225.1 - 2.2e-12 47.1 0.0 5.9e-12 45.7 0.0 1.7 2 1 0 2 2 2 1 DJ-1/PfpI family GATase_3 PF07685.14 OAP60225.1 - 0.1 12.2 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain GMC_oxred_C PF05199.13 OAP60226.1 - 5.5e-09 36.7 0.3 1.9e-08 34.9 0.2 2.0 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_N PF00732.19 OAP60226.1 - 9.9e-09 35.0 0.0 4.9e-08 32.7 0.0 2.0 1 1 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 OAP60226.1 - 4.6e-05 22.7 0.1 7.4e-05 22.0 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Hydrolase_4 PF12146.8 OAP60226.1 - 0.0031 16.8 0.1 0.7 9.1 0.0 3.3 4 0 0 4 4 4 1 Serine aminopeptidase, S33 FAD_oxidored PF12831.7 OAP60226.1 - 0.0046 16.3 0.5 0.0073 15.7 0.5 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAP60226.1 - 0.0075 15.5 0.1 0.014 14.7 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAP60226.1 - 0.014 15.6 0.5 0.044 14.0 0.5 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 OAP60226.1 - 0.09 11.5 0.1 0.16 10.7 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.19 OAP60226.1 - 0.093 12.0 0.2 0.17 11.1 0.2 1.4 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 OAP60226.1 - 0.13 11.3 0.1 0.2 10.7 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox PF00070.27 OAP60226.1 - 0.15 12.6 0.1 0.4 11.3 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SpoIIM PF01944.17 OAP60227.1 - 0.089 12.8 3.6 0.15 12.0 3.6 1.4 1 0 0 1 1 1 0 Stage II sporulation protein M Lipase_GDSL_2 PF13472.6 OAP60228.1 - 2e-19 70.7 1.2 2.7e-19 70.2 1.2 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 OAP60228.1 - 3.1e-08 33.8 0.1 5.3e-08 33.1 0.1 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Sugar_tr PF00083.24 OAP60229.1 - 7e-97 325.1 16.9 8.1e-97 324.9 16.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP60229.1 - 2.2e-14 53.2 32.6 9.2e-10 38.0 13.2 2.4 1 1 0 2 2 2 2 Major Facilitator Superfamily DUF4216 PF13952.6 OAP60229.1 - 0.082 13.3 0.2 0.24 11.8 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4216) CDH-cyt PF16010.5 OAP60230.1 - 9.4e-28 97.1 1.6 9.4e-28 97.1 1.6 2.0 2 1 0 2 2 2 1 Cytochrome domain of cellobiose dehydrogenase Cytochrom_B561 PF03188.16 OAP60230.1 - 2e-06 28.0 8.6 2e-06 28.0 8.6 1.9 3 0 0 3 3 3 1 Eukaryotic cytochrome b561 DUF2427 PF10348.9 OAP60230.1 - 0.00084 19.1 3.6 0.00084 19.1 3.6 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) DOMON PF03351.17 OAP60230.1 - 0.0018 18.5 0.1 0.0044 17.2 0.1 1.7 1 0 0 1 1 1 1 DOMON domain MerC PF03203.14 OAP60230.1 - 0.011 16.1 0.8 0.011 16.1 0.8 2.2 2 1 0 2 2 2 0 MerC mercury resistance protein SdpI PF13630.6 OAP60230.1 - 0.038 14.1 0.5 0.038 14.1 0.5 2.5 2 1 0 2 2 2 0 SdpI/YhfL protein family COX1 PF00115.20 OAP60230.1 - 0.37 9.6 14.1 11 4.8 14.7 2.0 1 1 0 1 1 1 0 Cytochrome C and Quinol oxidase polypeptide I Chorion_2 PF03964.15 OAP60230.1 - 0.42 11.5 13.1 0.1 13.5 4.1 3.2 3 0 0 3 3 3 0 Chorion family 2 DUF4079 PF13301.6 OAP60230.1 - 0.97 9.6 8.1 1.3 9.2 3.0 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF4079) ERAP1_C PF11838.8 OAP60231.1 - 0.088 12.3 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 ERAP1-like C-terminal domain Ribosomal_S11 PF00411.19 OAP60232.1 - 7.3e-47 158.3 1.0 9.1e-47 158.0 1.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 CBM_25 PF03423.13 OAP60232.1 - 0.14 12.4 0.0 0.26 11.6 0.0 1.4 1 0 0 1 1 1 0 Carbohydrate binding domain (family 25) AAR2 PF05282.11 OAP60233.1 - 1.9e-76 257.8 0.0 5.6e-76 256.2 0.0 1.6 1 1 0 1 1 1 1 AAR2 protein Ribosomal_S9 PF00380.19 OAP60234.1 - 1.7e-34 118.9 0.2 1.9e-34 118.8 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Exo70 PF03081.15 OAP60234.1 - 0.19 10.7 0.5 0.25 10.4 0.5 1.1 1 0 0 1 1 1 0 Exo70 exocyst complex subunit Ribosomal_L13 PF00572.18 OAP60235.1 - 2e-44 150.8 0.0 2.6e-44 150.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 Uricase PF01014.18 OAP60236.1 - 1.8e-80 267.6 2.4 3.9e-42 143.6 1.3 2.0 2 0 0 2 2 2 2 Uricase RICTOR_N PF14664.6 OAP60237.1 - 8.8e-125 416.6 0.4 1.4e-124 415.9 0.4 1.3 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.6 OAP60237.1 - 9.2e-36 121.8 1.0 1.2e-34 118.2 0.1 3.2 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.6 OAP60237.1 - 8.6e-35 119.4 0.2 1.3e-33 115.6 0.0 3.0 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.6 OAP60237.1 - 6.8e-28 96.7 0.7 6.3e-26 90.4 0.1 3.4 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.16 OAP60237.1 - 4.7e-15 55.5 10.4 1.4e-14 53.9 10.4 1.9 1 0 0 1 1 1 1 Hr1 repeat Proteasom_PSMB PF10508.9 OAP60237.1 - 0.0065 15.0 0.0 0.81 8.1 0.0 3.4 3 1 1 4 4 4 1 Proteasome non-ATPase 26S subunit Arm PF00514.23 OAP60237.1 - 0.018 15.1 0.0 0.21 11.7 0.1 2.9 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat Uds1 PF15456.6 OAP60237.1 - 0.79 9.9 8.9 0.55 10.4 6.8 1.8 2 0 0 2 2 2 0 Up-regulated During Septation LON_substr_bdg PF02190.16 OAP60238.1 - 1.5e-25 90.3 0.0 2.6e-25 89.5 0.0 1.4 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain zf-C3HC4_2 PF13923.6 OAP60238.1 - 5.2e-14 51.8 19.2 8.5e-12 44.7 10.9 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAP60238.1 - 8.7e-11 41.6 20.9 1.3e-07 31.5 10.3 2.4 2 0 0 2 2 2 2 zinc-RING finger domain zf-C3HC4 PF00097.25 OAP60238.1 - 1.4e-09 37.6 17.8 3.3e-06 26.9 9.8 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OAP60238.1 - 2.8e-09 37.0 20.1 3e-05 24.1 8.9 2.7 2 1 0 2 2 2 2 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 OAP60238.1 - 6.5e-09 35.5 15.4 2.2e-07 30.7 7.3 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAP60238.1 - 1.6e-08 34.4 20.1 3e-06 27.1 7.5 2.5 2 0 0 2 2 2 2 RING-type zinc-finger zf-RING_2 PF13639.6 OAP60238.1 - 1.1e-07 32.1 21.5 9.2e-07 29.1 10.0 2.5 2 0 0 2 2 2 2 Ring finger domain zf-RING_10 PF16685.5 OAP60238.1 - 1.2e-05 25.3 6.3 1.2e-05 25.3 6.3 2.3 2 0 0 2 2 2 1 zinc RING finger of MSL2 Prok-RING_4 PF14447.6 OAP60238.1 - 1.9e-05 24.4 16.5 7.8e-05 22.5 8.0 2.7 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 OAP60238.1 - 0.0063 16.3 7.6 0.0063 16.3 7.6 2.9 3 1 0 3 3 3 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 OAP60238.1 - 0.0077 16.5 5.3 0.0077 16.5 5.3 1.9 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-RING_6 PF14835.6 OAP60238.1 - 0.012 15.5 10.2 0.25 11.2 3.8 2.4 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-P11 PF03854.14 OAP60238.1 - 0.11 12.2 5.2 0.4 10.4 5.2 1.9 1 0 0 1 1 1 0 P-11 zinc finger zf-WRNIP1_ubi PF18279.1 OAP60238.1 - 0.91 10.3 5.5 2.1 9.2 1.4 3.4 2 1 0 2 2 2 0 Werner helicase-interacting protein 1 ubiquitin-binding domain Zn_Tnp_IS91 PF14319.6 OAP60238.1 - 0.93 9.6 9.2 2 8.5 2.6 2.7 2 0 0 2 2 2 0 Transposase zinc-binding domain Baculo_IE-1 PF05290.11 OAP60238.1 - 1.2 9.1 4.6 2.3 8.2 0.5 2.3 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) Amidase PF01425.21 OAP60239.1 - 6.5e-55 186.9 0.1 2.6e-53 181.6 0.1 2.4 1 1 0 1 1 1 1 Amidase Glyco_hydro_43 PF04616.14 OAP60240.1 - 1.4e-73 247.7 0.4 1.8e-73 247.4 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 OAP60240.1 - 3.5e-12 46.5 0.0 5.2e-12 45.9 0.0 1.2 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain DUF1349 PF07081.11 OAP60240.1 - 0.04 13.6 0.0 0.066 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1349) Sugar_tr PF00083.24 OAP60241.1 - 4.2e-78 263.2 20.7 5.3e-78 262.9 20.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP60241.1 - 4.7e-26 91.5 19.6 1.8e-21 76.5 7.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 OAP60241.1 - 1.7e-05 23.5 2.3 1.7e-05 23.5 2.3 2.3 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Thioredoxin PF00085.20 OAP60242.1 - 6.3e-06 26.1 0.0 1.7e-05 24.7 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 OAP60242.1 - 0.00023 21.6 0.0 0.00045 20.6 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 OAP60242.1 - 0.0042 16.5 0.0 0.0069 15.8 0.0 1.3 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family DUF3741 PF12552.8 OAP60242.1 - 0.076 13.0 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3741) PWI PF01480.17 OAP60244.1 - 7.7e-17 61.4 0.1 1.7e-16 60.3 0.1 1.6 1 0 0 1 1 1 1 PWI domain RRM_1 PF00076.22 OAP60244.1 - 0.0067 16.2 0.0 0.015 15.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Zn_clus PF00172.18 OAP60245.1 - 0.00024 21.2 11.7 0.0008 19.5 11.7 1.9 1 1 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NCA2 PF08637.10 OAP60246.1 - 1.1e-107 359.5 0.2 2.1e-107 358.6 0.2 1.5 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 Rox3 PF08633.10 OAP60246.1 - 0.013 15.8 0.0 0.024 14.9 0.0 1.4 1 0 0 1 1 1 0 Rox3 mediator complex subunit Ras PF00071.22 OAP60247.1 - 6e-65 217.8 0.0 7.3e-65 217.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAP60247.1 - 1.2e-33 115.9 0.1 1.7e-33 115.4 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAP60247.1 - 4.7e-13 49.0 0.0 5.8e-13 48.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OAP60247.1 - 4.5e-05 23.1 0.0 9e-05 22.1 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OAP60247.1 - 0.00023 20.6 0.0 0.00027 20.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 OAP60247.1 - 0.0018 18.2 0.1 1.8 8.4 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OAP60247.1 - 0.0031 17.6 0.0 0.0069 16.5 0.0 1.6 1 1 1 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.10 OAP60247.1 - 0.022 14.2 0.0 0.027 13.9 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 OAP60247.1 - 0.047 13.2 0.0 0.19 11.2 0.0 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_22 PF13401.6 OAP60247.1 - 0.12 12.7 0.1 0.53 10.6 0.1 2.0 1 1 0 1 1 1 0 AAA domain Profilin PF00235.19 OAP60248.1 - 5e-52 175.5 0.4 5.5e-52 175.4 0.4 1.0 1 0 0 1 1 1 1 Profilin Tox-ODYAM1 PF15642.6 OAP60248.1 - 0.096 11.6 0.1 0.12 11.3 0.1 1.1 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus adh_short_C2 PF13561.6 OAP60249.1 - 1.2e-52 178.8 2.3 1.5e-52 178.5 2.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP60249.1 - 7.8e-49 165.8 4.2 1e-48 165.4 4.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAP60249.1 - 3.4e-08 33.6 0.5 4.6e-08 33.2 0.5 1.1 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 OAP60249.1 - 0.0023 17.8 0.6 0.0035 17.2 0.6 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 OAP60249.1 - 0.0035 17.9 2.0 0.019 15.5 1.8 2.4 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Polysacc_synt_2 PF02719.15 OAP60249.1 - 0.018 14.2 1.1 0.024 13.8 1.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 OAP60249.1 - 0.022 15.0 0.2 0.058 13.7 0.1 1.7 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 OAP60249.1 - 0.045 13.2 0.2 0.11 12.0 0.1 1.6 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family NAD_binding_7 PF13241.6 OAP60249.1 - 0.092 13.2 0.4 0.18 12.3 0.4 1.6 1 1 0 1 1 1 0 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.19 OAP60249.1 - 0.11 11.9 0.3 0.17 11.2 0.3 1.4 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 OAP60249.1 - 0.14 12.2 0.8 0.24 11.5 0.7 1.5 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain DUF2545 PF10810.8 OAP60249.1 - 0.27 11.4 1.3 3.7 7.8 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2545) HET PF06985.11 OAP60250.1 - 1.2e-25 90.5 0.5 1.2e-25 90.5 0.5 2.0 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Utp21 PF04192.12 OAP60252.1 - 2e-64 217.3 0.6 2.9e-64 216.8 0.6 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain ANAPC4_WD40 PF12894.7 OAP60252.1 - 4.1e-14 52.6 0.0 0.00091 19.5 0.0 6.1 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OAP60252.1 - 2.2e-10 40.9 22.1 0.00034 21.3 0.6 9.0 10 0 0 10 10 10 2 WD domain, G-beta repeat Utp12 PF04003.12 OAP60252.1 - 0.00059 20.1 0.0 0.0012 19.1 0.0 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family PALB2_WD40 PF16756.5 OAP60252.1 - 0.0019 17.2 0.1 3.7 6.4 0.0 3.4 4 0 0 4 4 4 2 Partner and localizer of BRCA2 WD40 domain PQQ PF01011.21 OAP60252.1 - 0.0085 16.0 0.1 14 5.8 0.0 3.5 3 0 0 3 3 3 2 PQQ enzyme repeat WD40_like PF17005.5 OAP60252.1 - 0.01 15.2 4.4 0.44 9.8 0.3 4.0 2 2 1 3 3 3 0 WD40-like domain Cytochrom_D1 PF02239.16 OAP60252.1 - 0.04 12.4 0.0 0.25 9.8 0.0 2.0 2 0 0 2 2 2 0 Cytochrome D1 heme domain HPS3_N PF14761.6 OAP60252.1 - 0.15 11.6 0.0 7 6.1 0.0 2.6 2 0 0 2 2 2 0 Hermansky-Pudlak syndrome 3 His_Phos_2 PF00328.22 OAP60253.1 - 2.2e-108 363.1 0.3 3e-108 362.6 0.3 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 OAP60253.1 - 9e-32 109.1 0.0 2e-31 108.0 0.0 1.6 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 OAP60253.1 - 4.7e-08 32.8 0.0 1.1e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 RimK-like ATP-grasp domain BTK PF00779.19 OAP60254.1 - 0.0025 17.6 0.9 0.0071 16.1 0.9 1.8 1 0 0 1 1 1 1 BTK motif PRR20 PF15708.5 OAP60254.1 - 0.021 14.7 0.2 0.021 14.7 0.2 1.8 2 0 0 2 2 2 0 Proline-rich protein family 20 PGI PF00342.19 OAP60255.1 - 1.4e-233 775.9 1.0 1.6e-233 775.7 1.0 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase Arc_PepC PF06819.11 OAP60255.1 - 0.056 13.6 0.9 0.39 10.8 0.3 2.3 2 0 0 2 2 2 0 Archaeal Peptidase A24 C-terminal Domain CA_like PF10563.9 OAP60257.1 - 0.23 11.3 0.2 0.58 10.1 0.0 1.6 2 0 0 2 2 2 0 Putative carbonic anhydrase GMC_oxred_N PF00732.19 OAP60258.1 - 7.9e-67 225.7 0.0 3.1e-66 223.7 0.0 1.8 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAP60258.1 - 3.6e-34 118.3 0.2 6.6e-34 117.5 0.2 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 OAP60258.1 - 1.5e-06 27.6 0.6 0.024 13.7 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 OAP60258.1 - 0.00076 18.6 0.2 0.002 17.3 0.1 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 OAP60258.1 - 0.0021 18.2 0.0 0.0049 17.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 OAP60258.1 - 0.013 14.8 0.0 0.029 13.6 0.0 1.5 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.14 OAP60258.1 - 0.041 13.1 0.1 0.64 9.2 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAP60258.1 - 0.066 12.8 2.7 0.2 11.2 0.7 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 OAP60258.1 - 0.066 12.5 0.1 2.3 7.4 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAP60258.1 - 0.12 11.0 0.1 1.1 7.9 0.1 2.2 2 0 0 2 2 2 0 HI0933-like protein DAGK_cat PF00781.24 OAP60259.1 - 2.6e-11 43.2 0.0 4.3e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain PsbY PF06298.11 OAP60260.1 - 3.5 7.6 4.9 6.6 6.7 4.9 1.4 1 0 0 1 1 1 0 Photosystem II protein Y (PsbY) Metallophos PF00149.28 OAP60261.1 - 1.7e-11 45.0 1.0 2.8e-11 44.3 1.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OAP60261.1 - 7e-06 26.3 0.0 4.7e-05 23.6 0.0 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Pkinase PF00069.25 OAP60262.1 - 3.2e-40 138.2 0.0 2.9e-22 79.3 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAP60262.1 - 2.1e-13 50.2 0.1 6.4e-09 35.5 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAP60262.1 - 0.051 12.3 0.3 0.083 11.7 0.3 1.5 1 1 0 1 1 1 0 Fungal protein kinase PRIMA1 PF16101.5 OAP60263.1 - 1.1 9.3 7.2 0.36 10.9 0.7 2.3 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Pup PF05639.11 OAP60263.1 - 2.6 9.0 6.0 8 7.4 0.1 2.3 2 0 0 2 2 2 0 Pup-like protein Gemini_mov PF01708.16 OAP60264.1 - 0.12 12.2 0.0 0.4 10.5 0.0 1.9 1 0 0 1 1 1 0 Geminivirus putative movement protein FTR1 PF03239.14 OAP60264.1 - 0.18 11.0 0.4 0.25 10.5 0.4 1.1 1 0 0 1 1 1 0 Iron permease FTR1 family SLAC1 PF03595.17 OAP60265.1 - 1.6e-56 192.0 57.0 1.8e-56 191.8 57.0 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel eIF-3c_N PF05470.12 OAP60266.1 - 6.5e-173 576.2 28.2 6.5e-173 576.2 28.2 3.3 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 OAP60266.1 - 1.4e-14 54.5 1.1 1.5e-12 47.9 0.0 3.3 2 0 0 2 2 2 1 PCI domain DUF1385 PF07136.11 OAP60266.1 - 0.013 14.8 0.0 0.035 13.4 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1385) APP_E2 PF12925.7 OAP60266.1 - 1.3 8.7 11.1 0.37 10.5 0.6 3.3 3 0 0 3 3 3 0 E2 domain of amyloid precursor protein SDA1 PF05285.12 OAP60266.1 - 1.5 8.2 29.8 2.7 7.3 29.8 1.3 1 0 0 1 1 1 0 SDA1 Pkinase PF00069.25 OAP60267.1 - 3.5e-50 170.8 0.1 1.6e-49 168.7 0.1 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP60267.1 - 2.1e-23 83.0 0.1 6.5e-23 81.3 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 OAP60267.1 - 0.00023 21.2 7.8 0.00044 20.2 0.1 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 OAP60267.1 - 0.0028 17.3 0.1 0.011 15.4 0.1 1.9 1 1 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 OAP60267.1 - 0.68 9.5 2.7 0.33 10.5 0.2 1.7 2 0 0 2 2 2 0 Choline/ethanolamine kinase SNF2_N PF00176.23 OAP60268.1 - 9.8e-65 218.5 0.0 1.9e-64 217.6 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OAP60268.1 - 1.2e-18 67.5 0.0 4.3e-18 65.7 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAP60268.1 - 1.3e-05 25.3 0.0 5.8e-05 23.2 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit TFIIF_beta PF02270.15 OAP60268.1 - 0.059 13.5 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 TFIIF, beta subunit HTH domain EAP30 PF04157.16 OAP60269.1 - 6.6e-69 231.8 0.1 7.4e-69 231.6 0.1 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family Chlorophyllase PF07224.11 OAP60269.1 - 0.13 11.2 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Ribosomal_L30_N PF08079.12 OAP60270.1 - 1.3e-26 92.7 14.4 2.6e-26 91.6 14.4 1.6 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 OAP60270.1 - 2.4e-17 62.6 2.8 6.1e-17 61.3 2.8 1.8 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e GFA PF04828.14 OAP60271.1 - 2.8e-06 27.6 1.0 3.5e-06 27.3 0.1 1.6 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Zn_ribbon_SprT PF17283.2 OAP60271.1 - 0.054 13.4 0.4 0.054 13.4 0.4 3.0 3 0 0 3 3 3 0 SprT-like zinc ribbon domain DNA_pol_B PF00136.21 OAP60273.1 - 1.5e-118 396.4 3.2 2.9e-117 392.2 1.6 2.3 2 0 0 2 2 2 2 DNA polymerase family B zf-DNA_Pol PF08996.10 OAP60273.1 - 1.4e-67 227.0 4.4 3.3e-67 225.8 4.4 1.7 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.19 OAP60273.1 - 6.5e-41 140.6 0.0 1.3e-40 139.6 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.8 OAP60273.1 - 5.9e-25 87.1 8.2 5.9e-25 87.1 8.2 3.0 3 0 0 3 3 3 1 DNA polymerase alpha subunit p180 N terminal DNA_pol_B_2 PF03175.13 OAP60273.1 - 0.0008 18.4 0.3 0.002 17.1 0.0 1.7 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral MGDG_synth PF06925.11 OAP60273.1 - 0.18 11.9 0.1 0.66 10.1 0.0 2.0 2 0 0 2 2 2 0 Monogalactosyldiacylglycerol (MGDG) synthase Phos_pyr_kin PF08543.12 OAP60274.1 - 3.3e-78 262.5 4.0 4.7e-78 262.0 4.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.16 OAP60274.1 - 4.3e-49 167.2 0.6 6.4e-49 166.6 0.6 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.24 OAP60274.1 - 0.00044 19.6 0.1 0.0014 18.0 0.0 1.7 2 0 0 2 2 2 1 pfkB family carbohydrate kinase HK PF02110.15 OAP60274.1 - 0.003 17.0 2.1 0.015 14.7 0.3 2.3 2 0 0 2 2 2 1 Hydroxyethylthiazole kinase family Methyltransf_28 PF02636.17 OAP60275.1 - 5.2e-75 252.5 0.0 6.3e-75 252.2 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PPR_2 PF13041.6 OAP60277.1 - 1.3e-24 86.1 0.0 4.9e-19 68.3 0.0 2.8 2 0 0 2 2 2 2 PPR repeat family PPR PF01535.20 OAP60277.1 - 7.4e-06 25.9 0.2 0.0036 17.4 0.0 4.2 4 0 0 4 4 4 1 PPR repeat PPR_3 PF13812.6 OAP60277.1 - 1.4e-05 25.0 0.0 0.019 15.1 0.0 3.7 3 1 1 4 4 4 2 Pentatricopeptide repeat domain PPR_1 PF12854.7 OAP60277.1 - 1.9e-05 24.2 0.0 0.34 10.6 0.0 4.2 3 1 0 3 3 3 2 PPR repeat PPR_long PF17177.4 OAP60277.1 - 0.01 15.2 0.0 0.027 13.9 0.0 1.7 1 0 0 1 1 1 0 Pentacotripeptide-repeat region of PRORP Polysacc_deac_1 PF01522.21 OAP60277.1 - 0.14 12.0 0.4 1.1 9.2 0.1 2.6 2 1 1 3 3 3 0 Polysaccharide deacetylase FOXP-CC PF16159.5 OAP60278.1 - 0.11 13.2 0.9 0.22 12.2 0.9 1.6 1 1 0 1 1 1 0 FOXP coiled-coil domain zf-C2H2 PF00096.26 OAP60278.1 - 0.16 12.5 0.2 0.29 11.7 0.2 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type Med3 PF11593.8 OAP60278.1 - 0.16 11.1 6.5 0.21 10.7 6.5 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal YabA PF06156.13 OAP60278.1 - 4.7 7.9 6.0 2.4 8.8 0.2 2.1 1 1 1 2 2 2 0 Initiation control protein YabA DEAD PF00270.29 OAP60280.1 - 6.8e-50 169.3 0.0 1.5e-48 164.9 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAP60280.1 - 5.7e-31 107.2 0.0 2e-30 105.4 0.0 2.0 2 1 1 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAP60280.1 - 4e-05 23.7 0.0 0.00012 22.1 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 OAP60280.1 - 0.0022 18.4 0.0 0.96 9.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain Helicase_C_2 PF13307.6 OAP60280.1 - 0.0053 16.9 0.0 0.0091 16.2 0.0 1.3 1 0 0 1 1 1 1 Helicase C-terminal domain UTP25 PF06862.12 OAP60280.1 - 0.007 15.2 0.1 1.1 7.9 0.0 2.3 2 0 0 2 2 2 2 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 ERCC3_RAD25_C PF16203.5 OAP60280.1 - 0.012 14.8 0.1 0.018 14.3 0.1 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase DUF5335 PF17269.2 OAP60280.1 - 0.037 13.9 0.1 0.064 13.1 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5335) AAA_22 PF13401.6 OAP60280.1 - 0.15 12.3 0.9 28 5.0 0.0 3.5 4 0 0 4 4 4 0 AAA domain Fungal_trans PF04082.18 OAP60281.1 - 6.5e-12 45.0 1.7 1.1e-11 44.3 0.7 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain QCR10 PF09796.9 OAP60281.1 - 0.081 13.0 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) TmoB PF06234.12 OAP60281.1 - 0.13 12.3 0.0 12 6.1 0.0 2.5 2 0 0 2 2 2 0 Toluene-4-monooxygenase system protein B (TmoB) Chitin_synth_1 PF01644.17 OAP60283.1 - 7e-78 260.2 0.2 9.9e-78 259.7 0.2 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 OAP60283.1 - 1.7e-27 95.1 0.1 4.3e-27 93.9 0.1 1.7 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 OAP60283.1 - 1.7e-21 76.5 0.7 1.3e-19 70.3 0.0 2.4 1 1 0 2 2 2 1 Chitin synthase Glyco_trans_2_3 PF13632.6 OAP60283.1 - 9.5e-07 28.9 0.3 9.5e-07 28.9 0.3 2.3 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Hist_deacetyl PF00850.19 OAP60285.1 - 7.3e-48 163.6 0.3 1.1e-47 163.0 0.3 1.2 1 0 0 1 1 1 1 Histone deacetylase domain ApbA_C PF08546.11 OAP60286.1 - 1.7e-27 96.1 0.0 4e-27 94.9 0.0 1.7 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 OAP60286.1 - 8.2e-25 87.2 0.0 1.2e-24 86.7 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA TGT PF01702.18 OAP60287.1 - 1.1e-91 307.7 0.0 1.3e-91 307.4 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase DND1_DSRM PF14709.7 OAP60288.1 - 0.07 13.4 0.0 0.13 12.5 0.0 1.4 1 1 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 R3H-assoc PF13902.6 OAP60290.1 - 5.4e-08 33.3 0.5 3.6e-07 30.6 0.4 2.2 2 0 0 2 2 2 1 R3H-associated N-terminal domain Syntaxin-6_N PF09177.11 OAP60290.1 - 0.021 15.3 0.5 0.062 13.9 0.2 1.9 2 0 0 2 2 2 0 Syntaxin 6, N-terminal DUF2533 PF10752.9 OAP60290.1 - 0.023 15.1 0.5 0.31 11.5 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2533) DUF1826 PF08856.11 OAP60290.1 - 0.14 12.1 0.5 0.24 11.3 0.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1826) Peptidase_M28 PF04389.17 OAP60291.1 - 3.8e-30 105.1 0.1 1e-29 103.7 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M28 Peptidase_M20 PF01546.28 OAP60291.1 - 9.7e-07 28.7 0.1 1.8e-06 27.8 0.1 1.6 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 DUF1774 PF08611.10 OAP60292.1 - 3.3e-35 120.3 1.8 3.3e-35 120.3 1.8 2.1 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF1774) TMEM192 PF14802.6 OAP60292.1 - 0.015 14.4 2.3 0.03 13.4 2.3 1.5 1 0 0 1 1 1 0 TMEM192 family Mtp PF03821.16 OAP60292.1 - 1.1 8.7 3.9 0.25 10.9 0.3 1.8 2 0 0 2 2 2 0 Golgi 4-transmembrane spanning transporter zf-ANAPC11 PF12861.7 OAP60293.1 - 0.033 14.3 2.0 0.064 13.3 2.0 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-4CXXC_R1 PF10497.9 OAP60293.1 - 0.14 12.4 1.4 0.27 11.5 1.4 1.4 1 0 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 zf-rbx1 PF12678.7 OAP60293.1 - 0.8 10.0 4.8 1.8 8.9 4.8 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain CNOT1_HEAT PF16418.5 OAP60294.1 - 0.19 11.8 0.2 0.66 10.0 0.1 1.9 2 0 0 2 2 2 0 CCR4-NOT transcription complex subunit 1 HEAT repeat Lactamase_B_4 PF13691.6 OAP60296.1 - 0.037 13.7 0.2 2.8 7.7 0.0 2.5 2 1 0 2 2 2 0 tRNase Z endonuclease ADH_N PF08240.12 OAP60297.1 - 6.3e-25 87.2 0.1 1.2e-24 86.2 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAP60297.1 - 5.4e-19 68.5 1.3 1e-18 67.6 0.1 2.1 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAP60297.1 - 1.1e-05 26.5 0.0 3.8e-05 24.8 0.0 1.9 3 0 0 3 3 3 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 OAP60297.1 - 0.0075 15.8 0.6 0.015 14.8 0.6 1.4 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 OAP60297.1 - 0.078 12.3 3.1 0.085 12.1 2.1 1.6 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain IGFBP PF00219.18 OAP60297.1 - 0.1 13.3 0.2 0.1 13.3 0.2 1.7 2 0 0 2 2 2 0 Insulin-like growth factor binding protein zf-AN1 PF01428.16 OAP60298.1 - 5.8e-22 77.6 30.8 6.2e-11 42.3 9.8 2.2 2 0 0 2 2 2 2 AN1-like Zinc finger IBR PF01485.21 OAP60298.1 - 0.0098 16.1 18.9 0.022 15.0 6.6 2.5 2 0 0 2 2 2 2 IBR domain, a half RING-finger domain Transp_Tc5_C PF04236.15 OAP60298.1 - 1.8 8.9 15.9 1.9 8.9 4.2 2.4 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain C1_4 PF07975.12 OAP60298.1 - 4 7.8 19.6 11 6.4 3.1 2.6 2 0 0 2 2 2 0 TFIIH C1-like domain zinc_ribbon_4 PF13717.6 OAP60298.1 - 9.9 6.2 9.2 12 5.9 0.9 2.9 2 0 0 2 2 2 0 zinc-ribbon domain Thymidylat_synt PF00303.19 OAP60299.1 - 2.6e-106 354.6 0.0 3.1e-106 354.4 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase Tyosinase_C PF18132.1 OAP60301.1 - 6.5e-28 97.8 0.0 9.9e-28 97.3 0.0 1.3 1 0 0 1 1 1 1 Tyosinase C-terminal domain Tyrosinase PF00264.20 OAP60301.1 - 1.3e-27 97.5 0.0 2.8e-27 96.5 0.0 1.5 1 0 0 1 1 1 1 Common central domain of tyrosinase Ank_2 PF12796.7 OAP60302.1 - 4.4e-18 65.6 0.1 1.5e-10 41.5 0.0 4.7 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 OAP60302.1 - 1.1e-16 60.4 11.4 0.00027 21.2 0.0 6.2 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.6 OAP60302.1 - 3.5e-15 56.2 0.5 4.9e-09 36.6 0.0 4.8 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAP60302.1 - 2.4e-14 52.0 3.1 0.0014 18.9 0.0 6.3 6 0 0 6 6 5 3 Ankyrin repeat Ank_5 PF13857.6 OAP60302.1 - 8.6e-13 48.2 5.0 0.00039 20.6 0.0 5.5 3 1 2 5 5 5 4 Ankyrin repeats (many copies) AAA_16 PF13191.6 OAP60302.1 - 2.5e-06 28.0 0.0 1.1e-05 25.9 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 OAP60302.1 - 5.3e-05 23.2 0.1 0.00017 21.6 0.1 1.8 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 OAP60302.1 - 0.00019 21.8 0.0 0.01 16.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain Abhydrolase_6 PF12697.7 OAP60302.1 - 0.00057 20.5 0.0 0.0024 18.5 0.0 2.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.14 OAP60302.1 - 0.022 14.3 0.0 0.042 13.3 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) PGAP1 PF07819.13 OAP60302.1 - 0.051 13.3 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein RNA_helicase PF00910.22 OAP60302.1 - 0.056 13.8 0.4 0.2 12.0 0.0 2.2 2 0 0 2 2 1 0 RNA helicase NB-ARC PF00931.22 OAP60302.1 - 0.059 12.5 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain zf_UBZ PF18439.1 OAP60302.1 - 0.064 12.9 0.8 0.13 11.8 0.8 1.6 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger KAP_NTPase PF07693.14 OAP60302.1 - 0.08 12.2 0.3 0.31 10.3 0.0 2.0 2 0 0 2 2 2 0 KAP family P-loop domain AAA_29 PF13555.6 OAP60302.1 - 0.14 11.9 0.0 0.37 10.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain zf-CSL PF05207.13 OAP60302.1 - 0.17 11.6 0.2 0.39 10.5 0.2 1.5 1 0 0 1 1 1 0 CSL zinc finger FMN_dh PF01070.18 OAP60304.1 - 2.1e-111 372.3 0.0 2.7e-111 372.0 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 OAP60304.1 - 1.5e-05 24.2 0.1 2.7e-05 23.4 0.1 1.5 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 OAP60304.1 - 2.6e-05 23.6 0.1 4.1e-05 22.9 0.1 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase ThiG PF05690.14 OAP60304.1 - 0.00048 19.5 0.0 0.79 9.0 0.0 2.6 2 1 1 3 3 3 2 Thiazole biosynthesis protein ThiG NMO PF03060.15 OAP60304.1 - 0.00062 19.3 0.2 0.00095 18.6 0.2 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.21 OAP60304.1 - 0.01 15.3 0.5 0.5 9.8 0.0 2.7 2 1 1 3 3 3 0 Histidine biosynthesis protein Anoctamin PF04547.12 OAP60305.1 - 1.2e-115 387.0 2.7 1.4e-115 386.7 2.7 1.0 1 0 0 1 1 1 1 Calcium-activated chloride channel DUF2207 PF09972.9 OAP60305.1 - 0.97 8.1 3.8 2.5 6.8 0.3 2.5 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) F-box PF00646.33 OAP60306.1 - 5.9e-05 22.8 0.1 0.00016 21.5 0.1 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 OAP60306.1 - 0.00015 21.6 0.3 0.00039 20.2 0.3 1.8 1 0 0 1 1 1 1 F-box-like Na_Ca_ex PF01699.24 OAP60307.1 - 1.8e-21 76.7 26.9 9.7e-15 54.8 11.1 3.9 5 0 0 5 5 5 2 Sodium/calcium exchanger protein YccF PF03733.13 OAP60307.1 - 1.9e-13 50.9 13.3 1.9e-13 50.9 13.3 4.9 6 0 0 6 6 6 1 Inner membrane component domain AAA PF00004.29 OAP60308.1 - 3.4e-44 150.5 0.0 5.3e-44 149.9 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OAP60308.1 - 3.7e-15 55.4 0.1 7.7e-15 54.4 0.1 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 OAP60308.1 - 2e-07 31.3 0.0 3.4e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 OAP60308.1 - 7.3e-07 29.7 0.1 4.5e-05 23.9 0.0 2.8 2 1 0 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 OAP60308.1 - 7.6e-07 29.2 0.0 1.9e-06 27.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Prot_ATP_ID_OB PF16450.5 OAP60308.1 - 2.6e-06 27.3 2.5 6.7e-06 26.0 2.5 1.8 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_22 PF13401.6 OAP60308.1 - 3e-05 24.3 0.2 0.0063 16.8 0.0 2.4 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 OAP60308.1 - 7e-05 22.6 0.0 0.00014 21.7 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 OAP60308.1 - 0.0011 18.7 0.0 0.002 17.9 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.13 OAP60308.1 - 0.0011 18.2 0.0 0.0023 17.2 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 OAP60308.1 - 0.0018 18.4 0.0 0.0036 17.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 OAP60308.1 - 0.006 17.1 0.0 0.029 14.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.11 OAP60308.1 - 0.0063 16.4 0.0 0.015 15.1 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 OAP60308.1 - 0.0076 15.6 0.1 0.018 14.4 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI ATPase PF06745.13 OAP60308.1 - 0.0077 15.6 0.0 0.019 14.3 0.0 1.6 1 0 0 1 1 1 1 KaiC AAA_28 PF13521.6 OAP60308.1 - 0.011 15.9 0.0 0.02 15.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 OAP60308.1 - 0.012 15.6 0.0 0.021 14.8 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 OAP60308.1 - 0.019 14.1 0.0 0.033 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.26 OAP60308.1 - 0.023 14.4 0.0 0.096 12.4 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain PhoH PF02562.16 OAP60308.1 - 0.027 13.9 0.0 0.098 12.1 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein AAA_7 PF12775.7 OAP60308.1 - 0.03 13.9 0.0 0.048 13.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region HR1 PF02185.16 OAP60308.1 - 0.032 14.3 0.9 0.081 13.0 0.9 1.7 1 0 0 1 1 1 0 Hr1 repeat RNA_helicase PF00910.22 OAP60308.1 - 0.04 14.3 0.0 0.069 13.5 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.6 OAP60308.1 - 0.044 13.8 0.0 0.073 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 OAP60308.1 - 0.044 13.5 0.0 0.1 12.3 0.0 1.6 2 0 0 2 2 2 0 AAA domain Prot_ATP_OB_N PF17758.1 OAP60308.1 - 0.065 12.9 0.1 0.24 11.1 0.1 2.0 1 1 0 1 1 1 0 Proteasomal ATPase OB N-terminal domain AAA_25 PF13481.6 OAP60308.1 - 0.066 12.8 0.1 0.21 11.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 OAP60308.1 - 0.091 11.8 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF2072 PF09845.9 OAP60308.1 - 0.14 12.4 0.1 0.25 11.6 0.1 1.4 1 0 0 1 1 1 0 Zn-ribbon containing protein NACHT PF05729.12 OAP60308.1 - 0.15 12.0 0.0 0.45 10.4 0.0 1.7 2 0 0 2 2 2 0 NACHT domain Zeta_toxin PF06414.12 OAP60308.1 - 0.16 11.2 0.0 0.28 10.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Inositol_P PF00459.25 OAP60309.1 - 9.7e-62 208.9 0.1 1.3e-61 208.5 0.1 1.1 1 0 0 1 1 1 1 Inositol monophosphatase family SPX PF03105.19 OAP60310.1 - 0.63 9.9 5.4 0.67 9.8 5.4 1.3 1 0 0 1 1 1 0 SPX domain Pterin_4a PF01329.19 OAP60311.1 - 1.6e-11 44.2 0.1 2.8e-11 43.4 0.1 1.4 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase DUF123 PF01986.16 OAP60311.1 - 0.085 13.4 0.0 0.14 12.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF123 FA_hydroxylase PF04116.13 OAP60312.1 - 1.6e-26 93.2 17.0 1.6e-26 93.2 17.0 2.3 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily MFS_1 PF07690.16 OAP60313.1 - 7.8e-46 156.6 46.2 1.3e-36 126.3 34.7 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Lactamase_B PF00753.27 OAP60316.1 - 4.6e-07 30.1 0.1 1e-06 28.9 0.1 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OAP60316.1 - 0.0093 15.5 0.0 0.018 14.6 0.0 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain DUF1775 PF07987.11 OAP60316.1 - 0.054 13.8 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unkown function (DUF1775) DUF4147 PF13660.6 OAP60316.1 - 0.16 11.5 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4147) p450 PF00067.22 OAP60317.1 - 9.5e-61 205.9 0.0 1.3e-60 205.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PRC PF05239.16 OAP60317.1 - 0.14 12.2 0.1 0.27 11.3 0.1 1.4 1 0 0 1 1 1 0 PRC-barrel domain Ank_2 PF12796.7 OAP60319.1 - 1.9e-58 195.0 1.7 1e-11 45.2 0.0 6.4 6 0 0 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAP60319.1 - 1.2e-45 153.3 0.5 3.9e-06 27.3 0.0 11.0 6 4 6 12 12 12 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAP60319.1 - 2.4e-45 147.3 6.3 3.8e-05 23.7 0.0 14.4 15 0 0 15 15 15 11 Ankyrin repeat Ank_5 PF13857.6 OAP60319.1 - 1e-38 130.9 4.5 1.2e-06 28.6 0.0 9.5 6 2 4 10 10 10 8 Ankyrin repeats (many copies) Ank PF00023.30 OAP60319.1 - 2e-25 88.0 11.5 0.028 14.9 0.0 13.1 14 1 1 15 15 15 5 Ankyrin repeat p450 PF00067.22 OAP60320.1 - 2.3e-34 119.0 0.0 2e-25 89.5 0.0 2.8 2 1 1 3 3 3 2 Cytochrome P450 adh_short PF00106.25 OAP60321.1 - 6.5e-38 130.2 0.0 9.5e-38 129.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP60321.1 - 5.5e-30 104.6 0.0 9.4e-30 103.9 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase TrkA_N PF02254.18 OAP60321.1 - 6.8e-05 23.1 0.0 0.00012 22.3 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain Epimerase PF01370.21 OAP60321.1 - 0.00095 18.7 0.0 0.0022 17.5 0.0 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.10 OAP60321.1 - 0.0036 17.2 0.3 0.011 15.6 0.1 1.8 2 1 0 2 2 2 1 KR domain DFP PF04127.15 OAP60321.1 - 0.01 15.7 0.3 0.019 14.8 0.3 1.5 1 1 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein UPF0146 PF03686.13 OAP60321.1 - 0.094 12.6 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) TSP_NTD PF17804.1 OAP60321.1 - 0.11 12.8 0.0 0.15 12.3 0.0 1.2 1 0 0 1 1 1 0 Tail specific protease N-terminal domain FAD_binding_3 PF01494.19 OAP60321.1 - 0.11 11.7 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.14 OAP60322.1 - 7e-11 41.9 0.0 1.6e-07 30.8 0.0 2.8 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAP60322.1 - 2.9e-09 36.6 0.0 3.9e-07 29.6 0.0 3.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 OAP60322.1 - 3.4e-07 29.1 0.0 3.5e-06 25.7 0.0 2.3 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Shikimate_DH PF01488.20 OAP60322.1 - 2e-06 27.9 0.3 0.0057 16.7 0.0 2.3 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase NAD_binding_8 PF13450.6 OAP60322.1 - 3.3e-05 24.0 0.0 0.00014 22.0 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAP60322.1 - 0.00015 21.5 1.5 0.52 9.8 1.0 2.6 2 0 0 2 2 2 2 FAD dependent oxidoreductase K_oxygenase PF13434.6 OAP60322.1 - 0.00052 19.2 0.0 0.068 12.3 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.24 OAP60322.1 - 0.0029 16.8 0.2 0.005 16.0 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain 2-Hacid_dh_C PF02826.19 OAP60322.1 - 0.017 14.5 0.0 0.038 13.4 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_9 PF13454.6 OAP60322.1 - 0.027 14.4 0.1 2.6 8.0 0.1 2.9 3 0 0 3 3 3 0 FAD-NAD(P)-binding NAD_binding_7 PF13241.6 OAP60322.1 - 0.065 13.7 0.0 8.1 6.9 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding Pyr_redox PF00070.27 OAP60322.1 - 0.081 13.5 0.8 11 6.7 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.17 OAP60322.1 - 0.24 12.0 1.6 32 5.2 0.0 2.6 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent MFS_1 PF07690.16 OAP60323.1 - 7.2e-14 51.5 52.1 4.7e-08 32.3 44.1 3.2 1 1 1 2 2 2 2 Major Facilitator Superfamily p450 PF00067.22 OAP60324.1 - 6.5e-69 232.8 0.0 8.1e-69 232.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 GST_N_3 PF13417.6 OAP60325.1 - 5.3e-07 30.0 0.0 0.00017 21.9 0.0 2.4 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OAP60325.1 - 3.8e-05 23.9 0.0 0.00026 21.3 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAP60325.1 - 0.00013 21.9 0.0 0.00031 20.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 OAP60325.1 - 0.015 15.6 0.0 0.04 14.3 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAP60326.1 - 0.00015 21.7 0.2 0.00036 20.5 0.2 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 OAP60326.1 - 0.00019 21.7 0.0 0.00031 21.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 OAP60326.1 - 0.00038 20.8 0.0 0.00062 20.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 OAP60326.1 - 0.06 13.7 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Unstab_antitox PF09720.10 OAP60326.1 - 0.069 13.2 0.1 0.17 12.0 0.1 1.5 1 0 0 1 1 1 0 Putative addiction module component HET PF06985.11 OAP60327.1 - 2.5e-06 27.9 0.0 0.00026 21.4 0.0 2.6 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Ammonium_transp PF00909.21 OAP60329.1 - 2.6e-106 355.7 32.2 3.2e-106 355.4 32.2 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DUF4231 PF14015.6 OAP60329.1 - 1.4 9.4 4.3 11 6.5 0.2 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) UQ_con PF00179.26 OAP60330.1 - 7.4e-21 74.3 0.1 1.1e-20 73.8 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OAP60330.1 - 0.04 13.6 0.0 0.75 9.5 0.0 2.3 2 1 0 2 2 2 0 Prokaryotic E2 family B MA3 PF02847.17 OAP60331.1 - 4.7e-29 100.7 0.2 1.3e-28 99.3 0.1 1.8 2 0 0 2 2 2 1 MA3 domain MIF4G PF02854.19 OAP60331.1 - 4e-13 49.5 0.1 7.6e-13 48.6 0.1 1.5 1 0 0 1 1 1 1 MIF4G domain DPM2 PF07297.12 OAP60332.1 - 1.5e-29 102.1 2.6 1.7e-29 102.0 2.6 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.12 OAP60332.1 - 0.00028 20.8 0.8 0.00029 20.7 0.8 1.1 1 0 0 1 1 1 1 PIG-P COX14 PF14880.6 OAP60332.1 - 0.017 15.0 0.1 0.017 15.0 0.1 1.9 2 0 0 2 2 2 0 Cytochrome oxidase c assembly LapA_dom PF06305.11 OAP60332.1 - 0.035 13.9 0.2 0.065 13.1 0.2 1.5 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain DUF4229 PF14012.6 OAP60332.1 - 0.069 13.2 6.9 0.39 10.9 6.9 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF4229) Baculo_p26 PF04766.12 OAP60333.1 - 0.042 13.3 0.0 0.077 12.5 0.0 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus p26 protein PFK PF00365.20 OAP60334.1 - 6.5e-183 606.5 0.0 2.8e-101 338.6 0.1 2.1 2 0 0 2 2 2 2 Phosphofructokinase CPSF_A PF03178.15 OAP60335.1 - 1.2e-90 304.1 0.0 3.9e-89 299.1 0.0 2.5 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.9 OAP60335.1 - 7.4e-24 84.2 0.0 2.2e-23 82.7 0.0 1.7 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term LMBR1 PF04791.16 OAP60336.1 - 5.2e-16 58.6 9.4 5.2e-16 58.6 9.4 2.3 1 1 1 2 2 2 2 LMBR1-like membrane protein X PF00739.19 OAP60338.1 - 0.22 11.6 2.1 0.38 10.9 2.1 1.4 1 0 0 1 1 1 0 Trans-activation protein X WD40 PF00400.32 OAP60339.1 - 3.9e-06 27.5 1.6 5.7 8.0 0.1 4.6 4 0 0 4 4 4 4 WD domain, G-beta repeat DUF1770 PF08589.10 OAP60339.1 - 0.11 13.5 1.2 0.25 12.3 0.1 2.1 2 0 0 2 2 2 0 Fungal protein of unknown function (DUF1770) DUF4611 PF15387.6 OAP60339.1 - 0.45 10.8 4.1 8.9 6.6 0.8 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Fungal_trans_2 PF11951.8 OAP60340.1 - 2.7e-11 42.9 3.1 3.8e-11 42.4 3.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain APG6 PF04111.12 OAP60341.1 - 8.1e-69 231.1 0.0 1.4e-68 230.4 0.0 1.4 1 0 0 1 1 1 1 Apg6 BARA domain APG6_N PF17675.1 OAP60341.1 - 1e-13 51.9 6.9 1.1e-12 48.6 6.9 2.5 1 1 0 1 1 1 1 Apg6 coiled-coil region CdvA PF18822.1 OAP60341.1 - 0.025 14.4 0.4 0.054 13.3 0.4 1.5 1 0 0 1 1 1 0 CdvA-like coiled-coil domain AAA_28 PF13521.6 OAP60341.1 - 0.044 14.0 0.0 0.094 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain TrkA_N PF02254.18 OAP60341.1 - 0.053 13.8 0.1 0.8 10.0 0.0 2.2 2 0 0 2 2 2 0 TrkA-N domain Scm3 PF10384.9 OAP60342.1 - 6.2e-18 64.3 2.1 3.6e-17 61.8 0.1 2.5 2 0 0 2 2 2 1 Centromere protein Scm3 zf-C2H2_4 PF13894.6 OAP60342.1 - 2.7 9.1 3.9 2.1 9.4 0.3 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger PALP PF00291.25 OAP60343.1 - 4.4e-66 223.3 0.2 5.3e-66 223.0 0.2 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme UPF0181 PF03701.14 OAP60343.1 - 0.066 12.8 0.1 0.45 10.2 0.0 2.3 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0181) Methyltransf_28 PF02636.17 OAP60344.1 - 1.8e-39 136.0 0.0 2.6e-39 135.4 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PRMT5 PF05185.16 OAP60344.1 - 0.05 13.5 0.0 0.082 12.8 0.0 1.3 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase P34-Arc PF04045.14 OAP60345.1 - 4.1e-107 357.4 0.4 4.9e-107 357.1 0.4 1.0 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc ARPC4 PF05856.12 OAP60345.1 - 0.00044 19.9 1.0 0.0018 17.9 0.7 2.1 2 1 0 2 2 2 1 ARP2/3 complex 20 kDa subunit (ARPC4) Hemerythrin PF01814.23 OAP60345.1 - 0.4 11.3 3.5 5 7.7 0.5 2.5 2 1 0 2 2 2 0 Hemerythrin HHE cation binding domain NAD_binding_1 PF00175.21 OAP60346.1 - 1.3e-14 54.7 0.0 2.7e-14 53.7 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Globin PF00042.22 OAP60346.1 - 1.9e-11 44.5 0.0 1.2e-10 41.9 0.0 2.2 3 0 0 3 3 3 1 Globin FAD_binding_6 PF00970.24 OAP60346.1 - 8e-06 26.1 0.0 1.2e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Protoglobin PF11563.8 OAP60346.1 - 9.3e-06 25.6 0.1 1.6e-05 24.9 0.1 1.3 1 0 0 1 1 1 1 Protoglobin NAD_binding_6 PF08030.12 OAP60346.1 - 2.7e-05 24.4 0.0 0.0007 19.7 0.0 2.1 2 0 0 2 2 2 1 Ferric reductase NAD binding domain WD40 PF00400.32 OAP60348.1 - 4.3e-50 166.6 31.0 1.2e-05 26.0 0.0 12.9 12 1 0 12 12 12 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAP60348.1 - 1e-21 77.0 6.9 0.014 15.7 0.0 9.9 5 3 5 11 11 11 7 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 OAP60348.1 - 3.2e-16 59.6 0.1 6.3e-16 58.6 0.1 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family Ge1_WD40 PF16529.5 OAP60348.1 - 8.2e-09 34.9 6.3 0.13 11.1 0.2 6.7 4 3 2 6 6 6 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 OAP60348.1 - 5.5e-05 21.7 0.1 0.066 11.5 0.0 3.4 3 0 0 3 3 3 1 WD repeat-containing and planar cell polarity effector protein Fritz WD40_like PF17005.5 OAP60348.1 - 0.00067 19.1 0.2 0.51 9.6 0.0 3.6 3 1 0 3 3 3 1 WD40-like domain Nup160 PF11715.8 OAP60348.1 - 0.00093 18.0 10.5 0.32 9.6 0.1 5.8 5 2 2 7 7 7 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 OAP60348.1 - 0.008 15.0 1.1 0.4 9.4 0.1 3.6 3 1 0 3 3 3 1 Nup133 N terminal like eIF2A PF08662.11 OAP60348.1 - 0.01 15.8 0.3 7.9 6.3 0.0 4.5 4 1 1 5 5 5 0 Eukaryotic translation initiation factor eIF2A HPS3_N PF14761.6 OAP60348.1 - 0.025 14.1 0.2 1.4e+02 1.9 0.0 5.0 4 1 2 6 6 6 0 Hermansky-Pudlak syndrome 3 RAB3GAP2_N PF14655.6 OAP60348.1 - 0.044 13.0 0.1 4.7 6.4 0.0 3.3 2 1 0 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Hira PF07569.11 OAP60348.1 - 0.095 12.4 0.9 4.4 7.0 0.1 3.6 4 1 1 5 5 5 0 TUP1-like enhancer of split Myb_DNA-binding PF00249.31 OAP60349.1 - 1.9e-25 88.8 1.9 1.4e-14 54.0 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OAP60349.1 - 8.2e-20 70.8 1.3 4.7e-14 52.4 0.0 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain DUF2774 PF11242.8 OAP60349.1 - 0.056 13.6 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2774) HTH_23 PF13384.6 OAP60349.1 - 0.091 12.6 0.1 0.23 11.3 0.1 1.6 1 0 0 1 1 1 0 Homeodomain-like domain Glyco_transf_41 PF13844.6 OAP60350.1 - 1.5e-93 313.8 0.2 3.8e-46 157.5 0.0 3.6 3 1 0 3 3 3 2 Glycosyl transferase family 41 TPR_1 PF00515.28 OAP60350.1 - 1.4e-16 59.5 9.9 9.7e-05 22.0 0.2 5.6 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 OAP60350.1 - 2.7e-16 58.3 10.8 0.00084 19.3 0.3 5.8 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_8 PF13181.6 OAP60350.1 - 1.2e-12 47.0 5.8 0.029 14.6 0.0 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 OAP60350.1 - 1.5e-11 44.1 13.8 0.0003 21.4 1.1 6.0 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.6 OAP60350.1 - 1.8e-11 44.2 9.2 0.00014 22.1 0.3 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 OAP60350.1 - 1.9e-10 40.3 16.8 0.0076 16.1 1.6 6.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 OAP60350.1 - 4.7e-09 35.8 16.8 0.00068 19.3 0.6 6.2 5 1 2 7 7 7 3 TPR repeat TPR_17 PF13431.6 OAP60350.1 - 1.7e-08 34.2 6.0 0.56 10.7 0.1 5.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 OAP60350.1 - 4e-07 29.6 8.0 0.024 14.6 0.1 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 OAP60350.1 - 9.7e-07 29.3 16.2 1.8e-05 25.3 1.9 4.3 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 OAP60350.1 - 0.00038 20.9 12.8 0.0081 16.6 2.7 3.7 3 1 0 3 3 2 2 Tetratricopeptide repeat BTAD PF03704.17 OAP60350.1 - 0.064 13.7 7.7 0.11 12.9 0.1 3.0 4 0 0 4 4 3 0 Bacterial transcriptional activator domain ANAPC3 PF12895.7 OAP60350.1 - 3.3 8.0 7.5 1.2 9.4 0.6 2.9 3 0 0 3 3 2 0 Anaphase-promoting complex, cyclosome, subunit 3 ADK PF00406.22 OAP60351.1 - 5.9e-36 123.8 0.0 3e-20 72.9 0.0 2.1 2 0 0 2 2 2 2 Adenylate kinase ADK_lid PF05191.14 OAP60351.1 - 4.2e-15 55.4 0.0 6.8e-15 54.8 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.6 OAP60351.1 - 2.6e-14 53.8 0.1 7.4e-10 39.4 0.0 2.7 2 1 1 3 3 3 2 AAA domain AAA_18 PF13238.6 OAP60351.1 - 1.1e-05 25.9 0.0 2.8e-05 24.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 OAP60351.1 - 0.00066 19.9 0.1 0.0032 17.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain DUF1654 PF07867.11 OAP60351.1 - 0.02 14.6 0.1 0.039 13.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1654) AAA_28 PF13521.6 OAP60351.1 - 0.029 14.6 0.1 0.24 11.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 OAP60351.1 - 0.12 11.3 0.0 0.2 10.6 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_5 PF07728.14 OAP60351.1 - 0.13 12.2 0.0 0.37 10.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DNA_primase_lrg PF04104.14 OAP60352.1 - 1.8e-85 286.6 0.0 3.5e-85 285.6 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit DUF3533 PF12051.8 OAP60353.1 - 3.9e-85 286.0 11.6 4.9e-85 285.7 11.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) UL41A PF17591.2 OAP60353.1 - 3.3 7.9 6.3 7.9 6.7 0.5 2.6 2 0 0 2 2 2 0 Herpesvirus UL41A Cys_Met_Meta_PP PF01053.20 OAP60354.1 - 2.5e-133 444.3 0.0 2.8e-133 444.2 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 OAP60354.1 - 1.7e-06 27.2 0.1 4.9e-06 25.7 0.1 1.8 1 1 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 OAP60354.1 - 4.8e-06 26.1 0.0 8.6e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 OAP60354.1 - 1.8e-05 24.1 0.0 2.5e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 OAP60354.1 - 2.2e-05 24.0 0.1 4.9e-05 22.8 0.1 1.5 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Met_gamma_lyase PF06838.11 OAP60354.1 - 0.00069 18.3 0.0 0.00093 17.8 0.0 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase SepSecS PF05889.13 OAP60354.1 - 0.0026 16.5 0.0 0.0037 16.0 0.0 1.1 1 0 0 1 1 1 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Asparaginase_C PF17763.1 OAP60354.1 - 0.089 13.0 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 Glutaminase/Asparaginase C-terminal domain IMPDH PF00478.25 OAP60354.1 - 0.13 11.2 0.6 0.43 9.5 0.1 1.9 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain AA_kinase PF00696.28 OAP60355.1 - 9.4e-31 107.2 0.8 1.4e-30 106.7 0.1 1.6 2 0 0 2 2 2 1 Amino acid kinase family ACT PF01842.25 OAP60355.1 - 2.2e-11 43.3 4.1 1e-08 34.8 0.3 3.0 3 0 0 3 3 3 2 ACT domain ACT_7 PF13840.6 OAP60355.1 - 3.4e-09 36.3 1.9 3.4e-09 36.3 1.9 2.2 2 0 0 2 2 2 1 ACT domain RNA_pol_L PF01193.24 OAP60355.1 - 0.13 11.7 0.1 1.9 8.0 0.1 2.4 1 1 0 1 1 1 0 RNA polymerase Rpb3/Rpb11 dimerisation domain Abhydrolase_1 PF00561.20 OAP60356.1 - 7e-42 143.8 0.0 9.7e-42 143.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAP60356.1 - 3.2e-05 24.6 0.7 7.2e-05 23.5 0.7 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 OAP60356.1 - 4.1e-05 23.6 0.0 9.4e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein CN_hydrolase PF00795.22 OAP60357.1 - 1.1e-55 188.8 0.0 1.3e-55 188.6 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Zn_clus PF00172.18 OAP60358.1 - 1.2e-07 31.7 10.9 1.2e-07 31.7 10.9 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAP60358.1 - 6.2e-06 25.4 0.0 1.3e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain p450 PF00067.22 OAP60359.1 - 3.3e-53 181.1 0.0 3.2e-52 177.8 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 Chal_sti_synt_C PF02797.15 OAP60359.1 - 0.12 12.4 0.0 0.3 11.0 0.0 1.6 2 0 0 2 2 2 0 Chalcone and stilbene synthases, C-terminal domain MFS_1 PF07690.16 OAP60360.1 - 2e-37 128.9 35.2 5.2e-37 127.6 27.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAP60360.1 - 1.2e-11 44.1 28.2 2.4e-10 39.9 28.2 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter PUCC PF03209.15 OAP60360.1 - 0.00045 19.3 8.6 0.00045 19.3 8.6 2.7 3 1 0 3 3 3 1 PUCC protein OATP PF03137.20 OAP60360.1 - 0.0016 16.8 3.5 0.0069 14.7 3.5 2.2 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family PSI_PsaJ PF01701.18 OAP60360.1 - 0.052 14.1 0.1 0.18 12.3 0.1 1.9 1 0 0 1 1 1 0 Photosystem I reaction centre subunit IX / PsaJ Fungal_trans_2 PF11951.8 OAP60361.1 - 2.7e-52 177.9 0.8 3.2e-52 177.6 0.8 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP60361.1 - 2.4e-07 30.7 12.0 5.1e-07 29.7 12.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CorA PF01544.18 OAP60362.1 - 0.0001 21.7 0.6 0.00035 20.0 0.1 2.1 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein Acetyltransf_7 PF13508.7 OAP60363.1 - 2.5e-08 34.2 0.0 5.8e-08 33.1 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OAP60363.1 - 3.6e-08 33.4 0.0 5.8e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAP60363.1 - 2.4e-07 31.0 0.0 4.1e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 OAP60363.1 - 4.2e-05 23.6 0.0 0.031 14.4 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAP60363.1 - 0.00065 19.6 0.0 0.0012 18.7 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 OAP60363.1 - 0.047 13.8 0.0 0.083 13.0 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DIOX_N PF14226.6 OAP60364.1 - 1.2e-13 51.9 0.0 2e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OAP60364.1 - 6.5e-12 45.8 0.0 1.1e-11 45.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Sugar_tr PF00083.24 OAP60365.1 - 4.9e-29 101.5 27.1 8.6e-21 74.3 7.8 2.2 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 OAP60365.1 - 5.5e-18 65.0 40.1 1.3e-09 37.5 22.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ATG22 PF11700.8 OAP60365.1 - 0.17 10.5 11.5 0.072 11.7 0.8 2.7 3 0 0 3 3 3 0 Vacuole effluxer Atg22 like FMO-like PF00743.19 OAP60367.1 - 2.9e-18 65.6 0.0 7.7e-16 57.6 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OAP60367.1 - 6e-14 52.0 0.0 1.6e-12 47.3 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAP60367.1 - 1.6e-13 50.6 0.0 6.9e-11 41.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAP60367.1 - 1.2e-11 44.4 0.0 2e-09 37.1 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 OAP60367.1 - 4.7e-11 42.8 0.0 1.3e-09 38.1 0.0 2.8 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 OAP60367.1 - 1e-07 32.0 0.1 0.28 11.2 0.0 4.4 4 0 0 4 4 4 1 FAD-NAD(P)-binding DAO PF01266.24 OAP60367.1 - 5.6e-05 22.9 0.0 0.18 11.4 0.1 3.5 3 1 0 4 4 4 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 OAP60367.1 - 0.00015 22.2 0.1 0.23 12.0 0.0 2.9 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 OAP60367.1 - 0.0051 16.9 0.1 0.03 14.4 0.0 2.1 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase GIDA PF01134.22 OAP60367.1 - 0.018 14.2 0.0 0.47 9.5 0.0 2.5 3 0 0 3 3 3 0 Glucose inhibited division protein A Thi4 PF01946.17 OAP60367.1 - 0.018 14.3 0.3 0.057 12.7 0.0 1.8 2 0 0 2 2 2 0 Thi4 family Melibiase_C PF17801.1 OAP60367.1 - 0.086 12.9 0.0 7.9 6.6 0.0 2.6 2 0 0 2 2 2 0 Alpha galactosidase C-terminal beta sandwich domain Sugar_tr PF00083.24 OAP60368.1 - 5e-57 193.8 11.8 6.1e-57 193.5 11.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP60368.1 - 3.3e-22 78.9 27.5 2.9e-21 75.8 24.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 OAP60368.1 - 2.7e-05 22.7 1.3 0.049 11.9 0.1 2.6 2 1 1 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family MFS_2 PF13347.6 OAP60368.1 - 0.012 14.3 22.2 0.66 8.5 2.7 3.4 2 2 1 3 3 3 0 MFS/sugar transport protein PhyH PF05721.13 OAP60369.1 - 2.4e-20 73.7 0.0 3.4e-20 73.2 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) AA_permease_2 PF13520.6 OAP60370.1 - 1.5e-52 178.9 54.0 1.9e-52 178.6 54.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAP60370.1 - 6.1e-19 68.0 43.4 8.3e-19 67.5 43.4 1.1 1 0 0 1 1 1 1 Amino acid permease Fungal_trans_2 PF11951.8 OAP60371.1 - 1.1e-32 113.4 2.8 1.5e-32 112.9 2.8 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-Mss51 PF13824.6 OAP60373.1 - 3.7e-06 27.0 1.9 1e-05 25.6 1.9 1.7 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.18 OAP60373.1 - 1.5e-05 25.0 4.0 4.1e-05 23.6 4.0 1.8 1 0 0 1 1 1 1 MYND finger DUF3712 PF12505.8 OAP60374.1 - 8.2e-09 35.8 0.4 8e-07 29.4 0.1 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF3712) LEA_2 PF03168.13 OAP60374.1 - 7.5e-06 26.4 0.6 0.11 13.0 0.0 4.4 4 0 0 4 4 4 2 Late embryogenesis abundant protein SID-1_RNA_chan PF13965.6 OAP60374.1 - 0.095 11.1 1.0 0.13 10.6 1.0 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 UNC-50 PF05216.13 OAP60374.1 - 0.22 11.0 0.2 10 5.6 0.0 2.2 2 0 0 2 2 2 0 UNC-50 family DAG_kinase_N PF14513.6 OAP60374.1 - 7.8 6.7 20.8 17 5.6 20.8 1.6 1 0 0 1 1 1 0 Diacylglycerol kinase N-terminus S-methyl_trans PF02574.16 OAP60375.1 - 3.1e-64 217.4 0.0 3.6e-64 217.2 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase OTCace PF00185.24 OAP60376.1 - 2.1e-43 148.1 0.0 2.9e-43 147.7 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.21 OAP60376.1 - 1.4e-40 138.7 0.0 2.1e-40 138.1 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain DUF3984 PF13136.6 OAP60377.1 - 1.6e-31 109.9 20.2 8.1e-31 107.6 20.2 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF3984) S1-P1_nuclease PF02265.16 OAP60378.1 - 4.6e-63 213.4 0.4 5.8e-63 213.0 0.4 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease Nucleoporin_C PF03177.14 OAP60379.1 - 1.3e-111 374.2 0.1 1.7e-111 373.9 0.1 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.11 OAP60379.1 - 5.9e-51 173.6 0.0 8.2e-51 173.1 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like HABP4_PAI-RBP1 PF04774.15 OAP60380.1 - 0.19 12.6 2.3 0.31 11.9 2.3 1.5 1 1 0 1 1 1 0 Hyaluronan / mRNA binding family CIAPIN1 PF05093.13 OAP60381.1 - 1.8e-41 140.7 4.9 3.1e-41 139.9 4.9 1.3 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DRE2_N PF16803.5 OAP60381.1 - 6.7e-38 129.9 0.0 1.1e-37 129.3 0.0 1.3 1 0 0 1 1 1 1 Fe-S cluster assembly protein DRE2 N-terminus ALAD PF00490.21 OAP60382.1 - 2.9e-120 401.2 0.0 3.4e-120 401.0 0.0 1.1 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Zn_clus PF00172.18 OAP60383.1 - 3.2e-09 36.7 11.5 6.5e-09 35.8 11.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 OAP60383.1 - 0.00019 20.4 0.7 0.00037 19.4 0.1 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Ldl_recept_a PF00057.18 OAP60383.1 - 0.22 11.8 4.6 0.61 10.4 4.6 1.7 1 0 0 1 1 1 0 Low-density lipoprotein receptor domain class A GRAB PF10375.9 OAP60384.1 - 4.6e-09 35.8 0.1 8.6e-09 35.0 0.1 1.5 1 0 0 1 1 1 1 GRIP-related Arf-binding domain FAM184 PF15665.5 OAP60384.1 - 0.018 14.8 54.9 1 9.1 15.7 3.1 1 1 1 2 2 2 0 Family with sequence similarity 184, A and B HALZ PF02183.18 OAP60384.1 - 0.047 13.9 0.5 0.047 13.9 0.5 5.3 5 1 1 6 6 5 0 Homeobox associated leucine zipper CALCOCO1 PF07888.11 OAP60384.1 - 0.19 10.6 52.5 0.25 10.1 46.1 2.2 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF4407 PF14362.6 OAP60384.1 - 0.46 9.8 44.7 0.082 12.2 21.9 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Filament PF00038.21 OAP60384.1 - 0.5 9.9 51.5 2.8 7.5 0.8 3.1 1 1 2 3 3 3 0 Intermediate filament protein DUF3584 PF12128.8 OAP60384.1 - 0.69 7.4 52.7 0.17 9.4 19.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Golgin_A5 PF09787.9 OAP60384.1 - 0.75 9.2 54.3 0.46 9.9 20.7 3.3 1 1 2 3 3 3 0 Golgin subfamily A member 5 Ipi1_N PF12333.8 OAP60384.1 - 1.1 9.9 0.0 1.1 9.9 0.0 2.9 4 0 0 4 4 2 0 Rix1 complex component involved in 60S ribosome maturation Spc7 PF08317.11 OAP60384.1 - 1.7 7.5 58.9 2.6 6.8 22.4 3.8 1 1 3 4 4 4 0 Spc7 kinetochore protein DUF3450 PF11932.8 OAP60384.1 - 3.7 6.8 51.6 0.022 14.1 11.6 4.0 1 1 1 3 3 3 0 Protein of unknown function (DUF3450) CtIP_N PF10482.9 OAP60384.1 - 4.8 7.3 39.4 6.6 6.8 14.6 4.2 2 2 2 4 4 4 0 Tumour-suppressor protein CtIP N-terminal domain CENP-F_leu_zip PF10473.9 OAP60384.1 - 6 6.9 60.0 0.44 10.6 20.9 3.4 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Atg14 PF10186.9 OAP60384.1 - 6.5 5.7 42.4 0.23 10.5 21.1 2.5 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 GAS PF13851.6 OAP60384.1 - 6.8 6.0 52.7 28 4.0 26.8 3.0 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding Spindle_Spc25 PF08234.12 OAP60385.1 - 2.8e-09 37.0 0.0 7.4e-09 35.7 0.0 1.7 1 0 0 1 1 1 1 Chromosome segregation protein Spc25 Spc7 PF08317.11 OAP60385.1 - 0.016 14.1 9.4 0.021 13.7 9.4 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4472 PF14739.6 OAP60385.1 - 0.039 14.7 1.8 0.039 14.7 1.8 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) HAP1_N PF04849.13 OAP60385.1 - 0.065 12.4 10.0 0.093 11.9 10.0 1.1 1 0 0 1 1 1 0 HAP1 N-terminal conserved region DUF4407 PF14362.6 OAP60385.1 - 0.081 12.3 7.9 0.12 11.7 7.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Cob_adeno_trans PF01923.18 OAP60385.1 - 0.17 12.0 3.8 0.27 11.4 3.8 1.2 1 0 0 1 1 1 0 Cobalamin adenosyltransferase ADIP PF11559.8 OAP60385.1 - 0.23 11.6 16.5 0.55 10.3 16.4 1.6 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF724 PF05266.14 OAP60385.1 - 0.45 10.3 8.2 0.35 10.7 6.3 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF724) APG6_N PF17675.1 OAP60385.1 - 0.57 10.7 15.0 2.6 8.6 0.1 2.0 1 1 1 2 2 2 0 Apg6 coiled-coil region BRE1 PF08647.11 OAP60385.1 - 0.59 10.3 11.4 0.9 9.7 11.4 1.3 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase GBP_C PF02841.14 OAP60385.1 - 0.62 9.4 11.8 0.88 8.9 11.8 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain SlyX PF04102.12 OAP60385.1 - 0.69 10.6 13.3 0.24 12.0 5.3 2.7 1 1 1 2 2 2 0 SlyX Striatin PF08232.12 OAP60385.1 - 2.1 8.9 14.9 0.8 10.3 6.4 2.2 1 1 1 2 2 2 0 Striatin family DivIC PF04977.15 OAP60385.1 - 2.8 7.8 10.6 2 8.3 7.5 2.2 1 1 1 2 2 2 0 Septum formation initiator Cortex-I_coil PF09304.10 OAP60385.1 - 3.2 8.0 9.4 4.7 7.5 7.8 1.9 1 1 1 2 2 2 0 Cortexillin I, coiled coil DUF1664 PF07889.12 OAP60385.1 - 3.6 7.6 7.1 3.7 7.6 1.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) PKD_channel PF08016.12 OAP60386.1 - 0.018 13.7 8.4 0.43 9.2 2.3 2.3 2 0 0 2 2 2 0 Polycystin cation channel Methyltransf_25 PF13649.6 OAP60387.1 - 3.1e-08 34.2 0.0 1.5e-07 32.0 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAP60387.1 - 4.5e-08 33.6 0.0 1.2e-07 32.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAP60387.1 - 2.8e-06 26.8 0.0 4.7e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 OAP60387.1 - 5.5e-06 27.0 0.0 1.3e-05 25.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAP60387.1 - 0.00034 20.4 0.0 0.00056 19.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAP60387.1 - 0.063 13.1 0.0 0.15 11.9 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain cobW PF02492.19 OAP60388.1 - 6.6e-44 149.6 2.4 6.4e-33 113.8 0.2 2.2 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 OAP60388.1 - 5.5e-18 64.7 0.2 3e-12 46.3 0.0 2.5 2 0 0 2 2 2 2 Cobalamin synthesis protein cobW C-terminal domain AAA_16 PF13191.6 OAP60388.1 - 0.0015 19.0 0.1 0.0059 17.0 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain TsaE PF02367.17 OAP60388.1 - 0.02 14.9 0.0 0.041 13.9 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE T2SSE PF00437.20 OAP60388.1 - 0.025 13.6 0.0 0.048 12.7 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Viral_helicase1 PF01443.18 OAP60388.1 - 0.039 13.7 0.0 0.072 12.8 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_29 PF13555.6 OAP60388.1 - 0.045 13.5 0.2 0.11 12.3 0.2 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain NACHT PF05729.12 OAP60388.1 - 0.1 12.5 0.0 0.28 11.1 0.0 1.8 2 0 0 2 2 2 0 NACHT domain adh_short_C2 PF13561.6 OAP60389.1 - 2.7e-40 138.4 2.8 3.7e-40 138.0 0.2 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP60389.1 - 5.9e-36 123.8 1.2 8.9e-36 123.2 0.1 1.8 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 OAP60389.1 - 1.1e-08 35.3 0.4 7.5e-08 32.5 0.1 2.1 2 0 0 2 2 2 1 KR domain Smim3 PF17307.2 OAP60389.1 - 0.13 11.8 1.7 0.72 9.4 0.2 2.5 2 0 0 2 2 2 0 Small integral membrane protein 3 SGTA_dimer PF16546.5 OAP60390.1 - 2.4e-26 91.3 1.3 4.7e-26 90.4 1.3 1.5 1 0 0 1 1 1 1 Homodimerisation domain of SGTA TPR_2 PF07719.17 OAP60390.1 - 1.6e-14 52.8 4.9 4.2e-05 23.4 0.2 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 OAP60390.1 - 5.8e-13 48.1 5.2 0.0004 20.1 0.3 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 OAP60390.1 - 5.7e-11 41.9 5.0 7.9e-08 31.9 1.0 3.5 2 1 2 4 4 3 3 TPR repeat TPR_8 PF13181.6 OAP60390.1 - 5e-09 35.7 5.7 0.088 13.1 0.2 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 OAP60390.1 - 2.2e-07 30.4 0.1 0.017 15.1 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 OAP60390.1 - 1.8e-06 28.5 7.1 5.5e-06 26.9 1.5 2.8 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 OAP60390.1 - 3.7e-06 27.3 3.3 0.014 16.1 0.8 3.9 2 1 2 4 4 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 OAP60390.1 - 4.4e-05 23.6 2.5 0.0062 16.8 0.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 OAP60390.1 - 7.7e-05 22.9 1.9 0.0054 17.0 0.9 2.6 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 OAP60390.1 - 0.00025 21.5 1.2 0.0074 16.8 0.1 3.2 3 1 1 4 4 3 2 Tetratricopeptide repeat STI1 PF17830.1 OAP60390.1 - 0.00032 20.6 6.1 0.00032 20.6 6.1 2.9 3 0 0 3 3 3 1 STI1 domain TPR_9 PF13371.6 OAP60390.1 - 0.00049 20.2 0.1 0.019 15.1 0.1 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat BTAD PF03704.17 OAP60390.1 - 0.0087 16.5 0.5 0.17 12.3 0.1 2.2 2 0 0 2 2 2 1 Bacterial transcriptional activator domain TPR_15 PF13429.6 OAP60390.1 - 0.013 14.8 0.8 0.023 13.9 0.8 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.6 OAP60390.1 - 0.024 15.3 5.7 2.4 9.0 0.2 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat XPC-binding PF09280.11 OAP60390.1 - 0.029 14.1 0.8 0.029 14.1 0.8 2.4 2 0 0 2 2 2 0 XPC-binding domain TPR_10 PF13374.6 OAP60390.1 - 0.071 13.0 3.5 0.083 12.8 0.4 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.18 OAP60390.1 - 0.099 12.7 1.9 0.65 10.1 1.0 2.6 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain DUF5339 PF17274.2 OAP60390.1 - 0.3 12.0 0.2 0.3 12.0 0.2 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF5339) Wzy_C_2 PF11846.8 OAP60390.1 - 0.4 10.6 1.4 0.65 9.9 1.4 1.2 1 0 0 1 1 1 0 Virulence factor membrane-bound polymerase, C-terminal Peptidase_S28 PF05577.12 OAP60391.1 - 1.7e-35 122.6 0.0 2.3e-35 122.3 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S9 PF00326.21 OAP60391.1 - 0.0028 17.2 0.1 0.0066 15.9 0.0 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 OAP60391.1 - 0.19 10.9 0.0 0.31 10.3 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 PBP PF01161.20 OAP60394.1 - 1.3e-13 51.4 0.0 2.2e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein SOG2 PF10428.9 OAP60394.1 - 0.75 8.9 22.6 1.2 8.2 22.6 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein Plasmodium_Vir PF05795.11 OAP60394.1 - 2.6 7.4 3.6 3.3 7.0 3.6 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Macoilin PF09726.9 OAP60394.1 - 6.9 5.1 10.3 8.6 4.8 10.3 1.1 1 0 0 1 1 1 0 Macoilin family DUF3923 PF13061.6 OAP60395.1 - 0.039 14.0 3.1 5.5 7.2 0.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3923) PAF-AH_p_II PF03403.13 OAP60397.1 - 1.3e-07 30.5 0.0 1.7e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_1 PF00561.20 OAP60397.1 - 0.0038 16.9 0.0 0.0058 16.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAP60397.1 - 0.005 16.1 0.0 0.0066 15.7 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OAP60397.1 - 0.028 15.0 0.0 0.036 14.7 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Ub-RnfH PF03658.14 OAP60397.1 - 0.16 12.4 0.0 0.33 11.3 0.0 1.5 1 0 0 1 1 1 0 RnfH family Ubiquitin Mit_ribos_Mrp51 PF11709.8 OAP60398.1 - 3.8e-88 296.5 0.2 2.8e-87 293.7 0.2 1.9 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit Ribosomal_S17e PF00833.18 OAP60399.1 - 3.8e-60 201.2 0.4 4.5e-60 200.9 0.4 1.0 1 0 0 1 1 1 1 Ribosomal S17 Thioredoxin PF00085.20 OAP60400.1 - 7.7e-46 154.3 0.0 7.8e-24 83.6 0.0 4.3 3 1 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 OAP60400.1 - 2.3e-12 47.2 0.0 0.018 15.0 0.0 4.1 3 1 1 4 4 4 3 Thioredoxin-like domain HyaE PF07449.11 OAP60400.1 - 0.0001 22.2 0.0 1.1 9.2 0.0 3.9 4 0 0 4 4 4 1 Hydrogenase-1 expression protein HyaE Thioredoxin_8 PF13905.6 OAP60400.1 - 0.0066 16.7 0.0 6.7 7.1 0.0 3.9 4 1 0 4 4 4 1 Thioredoxin-like Thioredoxin_3 PF13192.6 OAP60400.1 - 0.098 12.7 0.1 0.62 10.2 0.0 2.3 2 0 0 2 2 2 0 Thioredoxin domain Thioredoxin_7 PF13899.6 OAP60400.1 - 0.23 11.6 1.1 5.8 7.2 0.1 3.4 4 0 0 4 4 4 0 Thioredoxin-like SH3-WW_linker PF16618.5 OAP60401.1 - 0.16 12.5 0.1 0.39 11.2 0.1 1.6 1 0 0 1 1 1 0 Linker region between SH3 and WW domains on ARHGAP12 Trypsin_2 PF13365.6 OAP60401.1 - 0.16 12.9 0.0 0.37 11.7 0.0 1.7 1 1 0 1 1 1 0 Trypsin-like peptidase domain E1_DerP2_DerF2 PF02221.15 OAP60402.1 - 6e-26 91.5 0.5 7e-26 91.2 0.5 1.1 1 0 0 1 1 1 1 ML domain Amidohydro_2 PF04909.14 OAP60403.1 - 8.7e-25 88.1 0.1 1e-24 87.9 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase MFS_1 PF07690.16 OAP60404.1 - 1.3e-26 93.4 29.9 1.3e-26 93.4 29.9 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily BT1 PF03092.16 OAP60404.1 - 0.00016 20.0 1.5 0.00016 20.0 1.5 2.0 2 0 0 2 2 2 1 BT1 family Response_reg PF00072.24 OAP60405.1 - 7.1e-21 74.5 0.0 1.6e-20 73.4 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 OAP60405.1 - 7.4e-20 71.5 0.2 1.4e-19 70.6 0.2 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 OAP60405.1 - 2.1e-12 46.9 0.0 6.5e-12 45.3 0.0 1.9 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.6 OAP60405.1 - 0.00026 21.3 0.0 0.00075 19.8 0.0 1.8 1 0 0 1 1 1 1 GAF domain ETC_C1_NDUFA5 PF04716.14 OAP60406.1 - 5.1e-27 93.5 3.5 3.4e-25 87.6 0.5 2.6 2 0 0 2 2 2 2 ETC complex I subunit conserved region QCR10 PF09796.9 OAP60407.1 - 2.5e-28 97.9 0.2 3.4e-28 97.5 0.2 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Acetyltransf_3 PF13302.7 OAP60408.1 - 3.4e-17 63.4 0.0 4.9e-17 62.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAP60408.1 - 1.7e-09 37.9 0.0 2.3e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 OAP60408.1 - 4.9e-08 33.3 0.0 6.1e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 OAP60408.1 - 6.5e-07 29.1 0.0 9e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OAP60408.1 - 0.0066 16.8 0.0 0.0096 16.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_18 PF18014.1 OAP60408.1 - 0.03 14.1 0.0 0.046 13.6 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OAP60408.1 - 0.066 13.2 0.0 0.089 12.7 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain ATP-synt_F PF01990.17 OAP60409.1 - 1.9e-34 117.8 0.1 2.2e-34 117.6 0.1 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit PDT PF00800.18 OAP60409.1 - 0.17 11.6 0.0 0.27 11.0 0.0 1.3 1 1 0 1 1 1 0 Prephenate dehydratase DUF2418 PF10332.9 OAP60410.1 - 5.7e-33 113.3 0.1 1.4e-32 112.1 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2418) DUF2105 PF09878.9 OAP60410.1 - 0.1 12.3 0.1 0.19 11.5 0.1 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2105) Fungal_trans PF04082.18 OAP60411.1 - 8.5e-09 34.8 2.1 1.4e-08 34.1 2.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain AMP-binding PF00501.28 OAP60412.1 - 4.7e-76 256.1 0.0 1.4e-75 254.5 0.0 1.7 2 0 0 2 2 2 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAP60412.1 - 2.9e-15 57.0 0.2 5.8e-15 56.0 0.2 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain adh_short_C2 PF13561.6 OAP60413.1 - 2.3e-41 141.9 0.0 2.8e-41 141.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP60413.1 - 3.9e-41 140.7 1.5 1.7e-39 135.3 0.0 2.0 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 OAP60413.1 - 0.00022 21.2 0.0 0.00035 20.5 0.0 1.3 1 0 0 1 1 1 1 KR domain TrkA_N PF02254.18 OAP60413.1 - 0.047 14.0 0.0 0.08 13.2 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain TPP_enzyme_C PF02775.21 OAP60413.1 - 0.048 13.5 0.0 0.087 12.6 0.0 1.5 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain HET PF06985.11 OAP60414.1 - 1.9e-06 28.3 0.7 0.00098 19.5 0.0 2.6 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) HET PF06985.11 OAP60415.1 - 3.5e-11 43.6 1.7 2.1e-08 34.6 0.0 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.16 OAP60416.1 - 2.6e-32 112.1 25.1 3.5e-32 111.7 25.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily ILVD_EDD PF00920.21 OAP60417.1 - 6.3e-203 675.1 0.5 7.2e-203 674.9 0.5 1.0 1 0 0 1 1 1 1 Dehydratase family Fungal_trans PF04082.18 OAP60418.1 - 1.1e-17 64.0 3.4 9.4e-17 60.9 1.4 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain Ebola_NP PF05505.12 OAP60419.1 - 0.014 13.8 0.0 0.019 13.3 0.0 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein DUF1752 PF08550.10 OAP60421.1 - 0.0019 18.0 0.5 0.0038 17.0 0.5 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) zf-H2C2_2 PF13465.6 OAP60422.1 - 5.6e-09 36.0 15.8 1.7e-08 34.5 6.4 3.5 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.26 OAP60422.1 - 1.5e-08 34.7 17.9 0.00011 22.5 1.9 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type Fungal_trans PF04082.18 OAP60422.1 - 2.5e-08 33.3 0.7 8.7e-08 31.5 0.7 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2_4 PF13894.6 OAP60422.1 - 2.6e-06 27.8 14.3 0.0034 18.1 1.1 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 OAP60422.1 - 0.00059 20.1 7.1 0.047 14.1 0.4 2.7 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 OAP60422.1 - 0.00083 19.6 5.1 0.11 12.8 0.1 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 OAP60422.1 - 0.0078 16.2 9.5 0.0094 15.9 0.4 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_11 PF16622.5 OAP60422.1 - 0.43 10.4 6.8 4 7.3 0.3 2.5 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2HC_2 PF13913.6 OAP60422.1 - 0.86 9.6 8.9 0.41 10.6 0.4 2.7 2 0 0 2 2 2 0 zinc-finger of a C2HC-type p450 PF00067.22 OAP60423.1 - 1.1e-76 258.5 0.0 1.4e-76 258.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 TRI12 PF06609.13 OAP60424.1 - 8.6e-49 166.5 22.5 1.1e-48 166.1 22.5 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAP60424.1 - 3.9e-23 82.0 45.0 3.9e-23 82.0 45.0 3.1 2 2 1 3 3 3 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAP60424.1 - 2.8e-13 49.5 8.3 5.3e-13 48.6 9.1 3.6 3 2 1 4 4 4 2 Sugar (and other) transporter DUF3522 PF12036.8 OAP60424.1 - 0.004 17.5 1.2 0.004 17.5 1.2 3.1 2 1 1 3 3 3 1 Protein of unknown function (DUF3522) DUF3784 PF12650.7 OAP60424.1 - 0.5 10.6 0.0 0.5 10.6 0.0 5.8 5 2 1 6 6 6 0 Domain of unknown function (DUF3784) DUF3464 PF11947.8 OAP60424.1 - 0.95 9.2 4.4 1.3 8.8 1.0 2.7 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 COesterase PF00135.28 OAP60425.1 - 2.5e-68 231.2 0.0 3.6e-68 230.7 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAP60425.1 - 2.1e-06 27.8 0.5 5.9e-05 23.0 0.2 2.7 2 1 0 2 2 2 1 alpha/beta hydrolase fold NmrA PF05368.13 OAP60426.1 - 6.5e-31 107.7 0.0 7.9e-31 107.4 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAP60426.1 - 1.9e-08 34.5 0.0 2.5e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAP60426.1 - 0.13 11.7 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family MFS_1 PF07690.16 OAP60427.1 - 4.4e-43 147.6 34.8 4.4e-43 147.6 34.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAP60427.1 - 1.1e-12 47.7 6.4 1.1e-12 47.7 6.4 2.6 2 1 1 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 OAP60427.1 - 6e-10 38.2 0.8 6e-10 38.2 0.8 1.7 1 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 OAP60427.1 - 2.7e-05 23.6 0.8 2.7e-05 23.6 0.8 2.2 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Antirestrict PF03230.13 OAP60427.1 - 0.14 12.2 0.0 1.2 9.2 0.0 2.3 2 0 0 2 2 2 0 Antirestriction protein CBM_14 PF01607.24 OAP60428.1 - 4.9e-09 36.2 4.4 5.7e-09 36.0 3.4 1.7 1 1 0 1 1 1 1 Chitin binding Peritrophin-A domain DUF4600 PF15372.6 OAP60430.1 - 0.38 11.2 5.1 1.6 9.1 4.7 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4600) Spc7 PF08317.11 OAP60430.1 - 1.3 7.8 9.6 2.2 7.1 9.6 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Cortex-I_coil PF09304.10 OAP60430.1 - 1.6 9.0 11.7 2.6 8.3 9.9 2.1 1 1 1 2 2 2 0 Cortexillin I, coiled coil kleA_kleC PF17383.2 OAP60430.1 - 5.8 7.3 9.1 12 6.3 1.7 3.0 1 1 2 3 3 3 0 Uncharacterized KorC regulated protein A CorA PF01544.18 OAP60430.1 - 6.5 6.0 9.5 12 5.1 9.5 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DHO_dh PF01180.21 OAP60431.1 - 6.5e-70 235.7 0.1 4.1e-58 196.9 0.0 2.1 2 0 0 2 2 2 2 Dihydroorotate dehydrogenase FMN_dh PF01070.18 OAP60431.1 - 0.0069 15.4 0.1 0.37 9.8 0.0 2.6 3 0 0 3 3 3 1 FMN-dependent dehydrogenase DUF4574 PF15141.6 OAP60431.1 - 0.11 12.4 0.1 0.11 12.4 0.1 2.3 2 0 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 NOG1_N PF17835.1 OAP60432.1 - 1.8e-48 164.5 0.0 1.8e-48 164.5 0.0 2.5 4 0 0 4 4 4 1 NOG1 N-terminal helical domain NOGCT PF08155.11 OAP60432.1 - 5.7e-27 93.5 2.7 1.1e-26 92.5 2.7 1.5 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.14 OAP60432.1 - 2e-25 88.3 0.2 4e-25 87.4 0.2 1.5 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.23 OAP60432.1 - 1e-15 57.8 0.0 2.2e-15 56.7 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OAP60432.1 - 1.5e-07 31.1 0.1 3.5e-07 29.9 0.1 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 OAP60432.1 - 0.0047 16.9 0.3 1.4 8.8 0.2 2.7 2 1 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 OAP60432.1 - 0.0064 16.6 0.0 3.8 7.6 0.0 2.6 1 1 1 2 2 2 2 Dynamin family Gtr1_RagA PF04670.12 OAP60432.1 - 0.0073 15.7 1.5 0.021 14.2 0.1 2.1 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region HEPN_AbiA_CTD PF18732.1 OAP60432.1 - 0.022 14.7 0.2 12 5.9 0.1 2.9 2 1 1 3 3 3 0 HEPN like, Abia C-terminal domain MBR1 PF17058.5 OAP60432.1 - 0.067 13.5 1.1 0.14 12.5 1.1 1.4 1 0 0 1 1 1 0 Mitochondrial biogenesis regulation protein 1 AAA_16 PF13191.6 OAP60432.1 - 0.095 13.1 1.7 0.35 11.2 0.0 2.8 2 2 0 2 2 2 0 AAA ATPase domain ADH_N PF08240.12 OAP60433.1 - 1.2e-07 31.5 0.0 2.2e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Zn_clus PF00172.18 OAP60437.1 - 2.7e-08 33.8 7.4 4.8e-08 33.0 7.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAP60437.1 - 5.1e-08 32.3 1.9 8.3e-08 31.6 1.9 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3425 PF11905.8 OAP60437.1 - 0.12 12.3 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3425) Got1 PF04178.12 OAP60438.1 - 2.7e-14 53.6 13.8 3.6e-14 53.2 13.8 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family AgrD PF05931.11 OAP60438.1 - 0.096 12.7 1.7 0.29 11.2 1.7 1.7 1 0 0 1 1 1 0 Staphylococcal AgrD protein TcpE PF12648.7 OAP60438.1 - 1.7 9.2 5.4 5 7.7 5.4 1.9 1 1 0 1 1 1 0 TcpE family CPP1-like PF11833.8 OAP60438.1 - 1.8 8.2 4.6 2.1 7.9 4.6 1.1 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Fungal_trans PF04082.18 OAP60439.1 - 2.8e-15 56.1 1.0 9.5e-14 51.1 0.2 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain DHC_N2 PF08393.13 OAP60439.1 - 0.056 12.5 0.1 0.088 11.9 0.1 1.2 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 2 End_N_terminal PF12218.8 OAP60439.1 - 0.1 12.3 0.0 0.97 9.2 0.0 2.5 2 0 0 2 2 2 0 N terminal extension of bacteriophage endosialidase Glyoxalase PF00903.25 OAP60440.1 - 1.6e-23 83.3 0.6 3.1e-16 59.8 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 OAP60440.1 - 2e-14 53.7 0.2 4.6e-06 26.9 0.0 2.4 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 OAP60440.1 - 1.4e-05 25.2 0.1 0.34 11.0 0.0 3.8 3 1 0 3 3 3 2 Glyoxalase-like domain Glyoxalase_5 PF14696.6 OAP60440.1 - 1.6e-05 25.1 0.3 0.00043 20.5 0.3 2.5 1 1 0 1 1 1 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase_6 PF18029.1 OAP60440.1 - 0.027 15.2 0.1 12 6.8 0.4 2.3 2 0 0 2 2 2 0 Glyoxalase-like domain TPR_17 PF13431.6 OAP60441.1 - 0.028 14.8 0.6 0.3 11.5 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat FMO-like PF00743.19 OAP60442.1 - 1.8e-49 168.6 0.0 2.5e-49 168.1 0.0 1.2 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OAP60442.1 - 2.2e-11 43.6 0.0 2.2e-10 40.3 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAP60442.1 - 0.00018 20.9 0.0 0.00048 19.4 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAP60442.1 - 0.01 16.1 0.0 0.026 14.7 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 OAP60442.1 - 0.011 15.0 0.1 0.018 14.3 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 OAP60442.1 - 0.051 12.3 0.0 2.4 6.7 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox PF00070.27 OAP60442.1 - 0.061 13.9 0.0 6.6 7.4 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAP60442.1 - 0.14 12.2 0.0 0.6 10.1 0.0 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding Snf7 PF03357.21 OAP60443.1 - 5.1e-11 42.5 9.9 8.6e-11 41.7 9.9 1.3 1 1 0 1 1 1 1 Snf7 Tam41_Mmp37 PF09139.11 OAP60443.1 - 0.34 10.3 2.0 0.55 9.6 2.0 1.3 1 0 0 1 1 1 0 Phosphatidate cytidylyltransferase, mitochondrial Amidase PF01425.21 OAP60444.1 - 2.9e-97 326.5 0.0 6.9e-96 321.9 0.0 2.0 1 1 0 1 1 1 1 Amidase Fungal_trans_2 PF11951.8 OAP60445.1 - 6.6e-10 38.3 0.7 9.4e-10 37.8 0.7 1.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain Peptidase_S10 PF00450.22 OAP60446.1 - 9.3e-60 203.2 0.1 1.3e-59 202.7 0.1 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Aminotran_1_2 PF00155.21 OAP60447.1 - 1.3e-39 136.4 0.0 1e-32 113.7 0.0 2.9 3 0 0 3 3 3 2 Aminotransferase class I and II OKR_DC_1 PF01276.20 OAP60447.1 - 0.19 10.4 0.1 0.61 8.8 0.1 1.7 1 1 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain DUF5519 PF17648.1 OAP60448.1 - 0.042 13.7 0.0 0.079 12.8 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5519) Na_Ca_ex PF01699.24 OAP60450.1 - 2.2e-33 115.4 35.6 3.8e-18 65.9 18.7 2.5 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF5418 PF17439.2 OAP60450.1 - 0.32 11.1 3.9 0.14 12.2 0.3 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5418) Phage_Coat_B PF05356.11 OAP60450.1 - 6.8 6.7 5.8 0.85 9.6 0.4 2.4 2 0 0 2 2 2 0 Phage Coat protein B Peptidase_S10 PF00450.22 OAP60451.1 - 1.6e-77 261.7 0.0 2e-77 261.4 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase CoA_trans PF01144.23 OAP60452.1 - 4.4e-89 297.6 3.0 7.6e-49 166.0 0.0 3.1 3 0 0 3 3 3 3 Coenzyme A transferase AcetylCoA_hyd_C PF13336.6 OAP60452.1 - 0.00012 22.1 0.2 0.00036 20.5 0.0 1.8 2 0 0 2 2 2 1 Acetyl-CoA hydrolase/transferase C-terminal domain TauD PF02668.16 OAP60453.1 - 3.7e-54 184.3 0.9 4.6e-54 184.0 0.9 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.16 OAP60454.1 - 4.9e-30 104.6 32.2 4.9e-30 104.6 32.2 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 OAP60454.1 - 0.0023 16.8 1.5 0.0054 15.6 0.0 2.3 2 1 0 2 2 2 1 MFS_1 like family Actin PF00022.19 OAP60455.1 - 6.6e-22 77.7 0.0 4.9e-19 68.2 0.0 2.7 3 0 0 3 3 3 2 Actin Pkinase_Tyr PF07714.17 OAP60456.1 - 6e-13 48.7 0.0 3.2e-12 46.3 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OAP60456.1 - 1.8e-12 47.2 0.0 1.3e-11 44.4 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain bZIP_1 PF00170.21 OAP60457.1 - 2.4e-06 27.5 15.2 5.1e-06 26.5 15.2 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 OAP60457.1 - 1.3e-05 25.2 17.4 3.4e-05 23.8 17.4 1.7 1 0 0 1 1 1 1 Basic region leucine zipper NAM-associated PF14303.6 OAP60457.1 - 0.13 13.0 6.8 0.28 11.9 6.8 1.5 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Arv1 PF04161.13 OAP60459.1 - 6.1e-65 219.3 0.0 8.3e-65 218.9 0.0 1.2 1 0 0 1 1 1 1 Arv1-like family TctB PF07331.11 OAP60459.1 - 3.5 7.9 8.9 16 5.7 3.9 2.2 1 1 1 2 2 2 0 Tripartite tricarboxylate transporter TctB family MFS_1 PF07690.16 OAP60460.1 - 2.1e-29 102.5 51.7 2.5e-27 95.7 14.9 2.9 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.13 OAP60460.1 - 1.5e-10 40.1 10.0 3.5e-10 39.0 10.0 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Phage-MuB_C PF09077.11 OAP60460.1 - 0.00089 19.1 0.1 0.0031 17.4 0.1 1.9 1 0 0 1 1 1 1 Mu B transposition protein, C terminal NAT PF04768.13 OAP60461.1 - 9.1e-51 171.9 0.0 6.5e-50 169.1 0.0 2.0 2 0 0 2 2 2 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase NAD_binding_2 PF03446.15 OAP60462.1 - 2.1e-31 109.2 0.1 3.5e-31 108.5 0.1 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 OAP60462.1 - 2.2e-13 50.6 0.1 1e-12 48.5 0.0 2.0 1 1 1 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_11 PF14833.6 OAP60462.1 - 3.3e-10 40.3 0.0 5.7e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Shikimate_DH PF01488.20 OAP60462.1 - 5.3e-09 36.3 0.0 1.2e-08 35.1 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 OAP60462.1 - 0.00089 19.5 0.0 0.0021 18.3 0.0 1.6 2 0 0 2 2 2 1 TrkA-N domain Ham1p_like PF01725.16 OAP60462.1 - 0.01 15.8 0.0 0.029 14.3 0.0 1.7 1 1 0 1 1 1 0 Ham1 family Sacchrp_dh_NADP PF03435.18 OAP60462.1 - 0.011 16.0 0.0 0.029 14.6 0.0 1.7 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain GFO_IDH_MocA PF01408.22 OAP60462.1 - 0.013 16.3 0.1 0.048 14.5 0.0 2.0 3 0 0 3 3 3 0 Oxidoreductase family, NAD-binding Rossmann fold IlvN PF07991.12 OAP60462.1 - 0.026 14.1 0.0 0.073 12.6 0.0 1.7 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain UDPG_MGDP_dh_N PF03721.14 OAP60462.1 - 0.049 13.2 0.2 0.17 11.4 0.2 1.8 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain PDH PF02153.17 OAP60462.1 - 0.073 12.1 0.1 0.11 11.5 0.1 1.2 1 0 0 1 1 1 0 Prephenate dehydrogenase NAD_binding_10 PF13460.6 OAP60462.1 - 0.088 12.7 0.0 0.19 11.6 0.0 1.6 2 0 0 2 2 2 0 NAD(P)H-binding FAD_binding_3 PF01494.19 OAP60463.1 - 9.8e-31 107.3 0.0 2.3e-30 106.0 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 OAP60463.1 - 4.8e-07 29.3 1.0 0.0071 15.6 0.1 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OAP60463.1 - 8.3e-05 21.8 1.2 0.0029 16.7 0.5 2.4 2 1 0 2 2 2 1 Lycopene cyclase protein SE PF08491.10 OAP60463.1 - 0.00012 21.2 0.0 0.00031 19.9 0.0 1.6 1 1 0 1 1 1 1 Squalene epoxidase Pyr_redox PF00070.27 OAP60463.1 - 0.00083 19.9 0.3 0.95 10.1 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAP60463.1 - 0.00092 19.4 0.7 0.0021 18.3 0.7 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 OAP60463.1 - 0.00097 18.5 0.4 0.29 10.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAP60463.1 - 0.012 14.7 2.8 0.029 13.5 1.2 2.2 1 1 2 3 3 3 0 FAD binding domain DAO PF01266.24 OAP60463.1 - 0.086 12.4 4.7 1.1 8.8 1.4 2.2 1 1 1 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.14 OAP60463.1 - 0.46 9.1 1.3 11 4.6 0.0 2.4 2 0 0 2 2 2 0 HI0933-like protein TPR_12 PF13424.6 OAP60464.1 - 9.9e-16 57.8 3.9 3.2e-09 36.9 0.1 4.1 3 1 1 4 4 4 2 Tetratricopeptide repeat Clr5 PF14420.6 OAP60464.1 - 2.1e-15 56.7 0.8 7.7e-15 54.9 0.3 2.3 2 0 0 2 2 2 1 Clr5 domain TPR_10 PF13374.6 OAP60464.1 - 6.9e-15 54.4 4.4 8.6e-05 22.3 0.2 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_MalT PF17874.1 OAP60464.1 - 0.00012 21.6 0.9 0.00012 21.6 0.9 2.7 2 2 1 3 3 3 1 MalT-like TPR region TPR_7 PF13176.6 OAP60464.1 - 0.00026 20.8 1.9 0.023 14.7 0.1 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 OAP60464.1 - 0.0037 17.9 11.1 1.4 10.0 0.1 5.4 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 OAP60464.1 - 0.0055 17.3 1.2 0.0055 17.3 1.2 3.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 OAP60464.1 - 0.0055 17.2 0.2 0.032 14.7 0.1 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_4 PF07721.14 OAP60464.1 - 0.022 15.3 9.6 5.9 7.8 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 OAP60464.1 - 0.065 13.4 1.5 12 6.3 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF2938 PF11158.8 OAP60464.1 - 0.15 11.5 0.1 0.27 10.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2938) Glyco_hydro_31 PF01055.26 OAP60466.1 - 1.7e-158 528.5 4.3 2.2e-158 528.1 4.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 OAP60466.1 - 1.9e-36 124.8 0.0 4.1e-36 123.7 0.0 1.6 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 OAP60466.1 - 1.5e-13 50.9 1.5 7e-13 48.7 1.5 2.3 1 0 0 1 1 1 1 Galactose mutarotase-like PAXX PF15384.6 OAP60466.1 - 0.2 11.3 0.5 0.35 10.5 0.5 1.3 1 0 0 1 1 1 0 PAXX, PAralog of XRCC4 and XLF, also called C9orf142 Amidase PF01425.21 OAP60467.1 - 4.6e-77 259.9 0.9 6.8e-77 259.3 0.9 1.3 1 0 0 1 1 1 1 Amidase Glyco_transf_28 PF03033.20 OAP60468.1 - 4e-18 65.8 0.1 1.5e-10 41.2 0.0 2.5 2 0 0 2 2 2 2 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 OAP60468.1 - 3.8e-06 26.0 0.0 7.3e-06 25.0 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase ATG_C PF09333.11 OAP60468.1 - 0.00029 21.1 0.0 0.0013 19.0 0.0 2.2 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain UIM PF02809.20 OAP60468.1 - 0.0011 18.7 18.2 0.91 9.6 1.7 5.1 4 0 0 4 4 4 3 Ubiquitin interaction motif Glyco_tran_28_C PF04101.16 OAP60468.1 - 0.1 12.5 0.2 0.53 10.2 0.0 2.3 2 0 0 2 2 2 0 Glycosyltransferase family 28 C-terminal domain adh_short_C2 PF13561.6 OAP60469.1 - 4e-38 131.3 0.6 6e-38 130.7 0.1 1.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP60469.1 - 4.5e-32 111.1 0.0 9.2e-32 110.1 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_deac_1 PF01522.21 OAP60469.1 - 4.9e-14 52.3 0.0 9.1e-14 51.4 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Epimerase PF01370.21 OAP60469.1 - 4.8e-05 22.9 0.0 0.00026 20.5 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family DUF2334 PF10096.9 OAP60469.1 - 7.9e-05 22.4 0.0 0.00014 21.5 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) KR PF08659.10 OAP60469.1 - 0.00067 19.6 0.0 0.0017 18.3 0.0 1.6 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 OAP60469.1 - 0.0066 16.4 0.0 0.016 15.1 0.0 1.6 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 OAP60469.1 - 0.016 14.6 0.0 0.025 14.0 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase NmrA PF05368.13 OAP60469.1 - 0.059 12.9 0.0 0.18 11.3 0.0 1.7 2 0 0 2 2 2 0 NmrA-like family 3Beta_HSD PF01073.19 OAP60469.1 - 0.064 12.2 0.0 0.095 11.7 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family AA_permease_2 PF13520.6 OAP60470.1 - 8.8e-51 173.1 45.9 1e-50 172.8 45.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAP60470.1 - 5.4e-24 84.6 40.2 7.6e-24 84.1 40.2 1.1 1 0 0 1 1 1 1 Amino acid permease DUF962 PF06127.11 OAP60470.1 - 0.00011 22.2 0.3 0.0031 17.6 0.0 3.0 2 1 0 2 2 2 1 Protein of unknown function (DUF962) SID-1_RNA_chan PF13965.6 OAP60470.1 - 0.46 8.8 3.3 0.88 7.9 3.3 1.4 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Ribosomal_S7 PF00177.21 OAP60471.1 - 7.5e-36 123.0 2.0 9.4e-36 122.7 2.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Zn_clus PF00172.18 OAP60472.1 - 0.0016 18.5 3.5 0.0035 17.4 3.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 OAP60472.1 - 0.012 14.4 2.3 0.031 13.1 0.1 2.1 2 0 0 2 2 2 0 Fungal specific transcription factor domain SDA1 PF05285.12 OAP60473.1 - 2.7e-98 329.6 37.2 2.7e-98 329.6 37.2 2.2 2 0 0 2 2 2 2 SDA1 NUC130_3NT PF08158.12 OAP60473.1 - 1.2e-22 79.9 0.1 5.1e-22 77.9 0.0 2.2 2 0 0 2 2 2 1 NUC130/3NT domain RNR_inhib PF08591.10 OAP60475.1 - 5.8e-13 50.1 2.0 4e-12 47.4 0.2 2.5 1 1 1 2 2 2 1 Ribonucleotide reductase inhibitor HET PF06985.11 OAP60476.1 - 0.0037 17.6 0.3 0.0087 16.4 0.3 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Mto2_bdg PF12808.7 OAP60477.1 - 0.0088 16.3 3.4 0.0088 16.3 3.4 2.9 3 0 0 3 3 3 1 Micro-tubular organiser Mto1 C-term Mto2-binding region Spc7 PF08317.11 OAP60477.1 - 0.15 11.0 23.6 0.47 9.3 23.6 1.8 1 0 0 1 1 1 0 Spc7 kinetochore protein GAS PF13851.6 OAP60477.1 - 1.5 8.2 27.8 5.2 6.4 8.0 2.8 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding MPS2 PF17060.5 OAP60477.1 - 3.7 6.7 9.5 5.9 6.0 7.0 2.2 2 0 0 2 2 2 0 Monopolar spindle protein 2 Ank_2 PF12796.7 OAP60478.1 - 4e-11 43.4 0.6 8.6e-10 39.1 0.3 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OAP60478.1 - 8.4e-06 26.0 3.0 0.004 17.4 0.9 3.5 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 OAP60478.1 - 9.8e-06 26.0 0.5 0.00017 22.1 0.4 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAP60478.1 - 0.0036 17.7 3.3 0.22 12.2 0.1 4.0 5 0 0 5 5 5 1 Ankyrin repeat Ank PF00023.30 OAP60478.1 - 0.029 14.8 8.4 0.07 13.6 0.1 3.9 3 1 0 3 3 3 0 Ankyrin repeat PNP_UDP_1 PF01048.20 OAP60479.1 - 5.9e-13 48.6 0.3 2.1e-12 46.8 0.3 1.7 1 1 0 1 1 1 1 Phosphorylase superfamily GGACT PF06094.12 OAP60480.1 - 1.9e-05 25.3 0.0 3.9e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like AIG2_2 PF13772.6 OAP60480.1 - 0.023 15.1 0.0 0.11 13.0 0.0 2.2 2 0 0 2 2 2 0 AIG2-like family Transferase PF02458.15 OAP60481.1 - 6.5e-22 77.8 0.0 2.1e-19 69.5 0.0 2.1 2 0 0 2 2 2 2 Transferase family BTB PF00651.31 OAP60482.1 - 4.1e-13 49.5 0.1 1.2e-11 44.8 0.0 2.5 3 0 0 3 3 3 1 BTB/POZ domain CALCOCO1 PF07888.11 OAP60482.1 - 0.0011 18.0 2.8 0.002 17.1 2.8 1.4 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like Skp1_POZ PF03931.15 OAP60482.1 - 0.054 13.7 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Skp1 family, tetramerisation domain CENP-Q PF13094.6 OAP60482.1 - 0.27 11.4 4.3 0.23 11.6 1.0 2.0 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit HIT PF01230.23 OAP60483.1 - 3.2e-21 75.9 0.0 4.8e-21 75.3 0.0 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 OAP60483.1 - 0.00011 22.6 0.0 0.00018 22.0 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 OAP60483.1 - 0.00055 19.8 0.0 0.00078 19.3 0.0 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 GalP_UDP_tr_C PF02744.17 OAP60483.1 - 0.078 12.7 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Galactose-1-phosphate uridyl transferase, C-terminal domain HD_3 PF13023.6 OAP60484.1 - 6.3e-47 159.6 0.0 8.2e-47 159.2 0.0 1.1 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 OAP60484.1 - 3.6e-12 46.4 0.0 4.5e-12 46.1 0.0 1.1 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 OAP60484.1 - 0.0058 16.8 0.0 0.011 16.0 0.0 1.4 1 0 0 1 1 1 1 HD domain Cytochrom_B561 PF03188.16 OAP60485.1 - 2.9e-09 37.2 9.0 5.9e-09 36.2 9.0 1.5 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF2306 PF10067.9 OAP60485.1 - 4.6e-05 23.7 1.5 4.6e-05 23.7 1.5 2.2 1 1 0 2 2 2 1 Predicted membrane protein (DUF2306) PepSY_TM PF03929.16 OAP60485.1 - 0.0007 19.4 4.1 0.0011 18.7 4.0 1.6 1 1 0 1 1 1 1 PepSY-associated TM region DUF4079 PF13301.6 OAP60485.1 - 0.1 12.7 14.9 1.8 8.7 13.5 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF4079) XK-related PF09815.9 OAP60485.1 - 0.12 11.4 6.2 0.18 10.8 3.5 2.3 2 1 0 2 2 2 0 XK-related protein Phage_holin_2_4 PF16082.5 OAP60485.1 - 0.15 11.8 0.1 0.15 11.8 0.1 2.0 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like RseC_MucC PF04246.12 OAP60485.1 - 0.53 10.2 3.4 14 5.6 0.1 2.5 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC MFS_1 PF07690.16 OAP60485.1 - 0.54 9.1 13.8 3.9 6.3 8.2 2.6 1 1 0 2 2 2 0 Major Facilitator Superfamily TraQ PF09679.10 OAP60485.1 - 0.68 9.9 6.9 3.6 7.6 1.0 3.7 2 1 2 4 4 4 0 Type-F conjugative transfer system pilin chaperone (TraQ) HET PF06985.11 OAP60486.1 - 1.9e-32 112.6 0.1 3.5e-32 111.8 0.1 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HAUS6_N PF14661.6 OAP60487.1 - 1.7e-36 125.9 0.1 3.6e-36 124.9 0.0 1.5 2 0 0 2 2 2 1 HAUS augmin-like complex subunit 6 N-terminus Vir_act_alpha_C PF10400.9 OAP60487.1 - 0.023 15.3 0.5 0.8 10.4 0.1 2.4 2 0 0 2 2 2 0 Virulence activator alpha C-term HrpB2 PF09487.10 OAP60487.1 - 0.065 13.7 0.2 0.15 12.5 0.2 1.6 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB2) ATG16 PF08614.11 OAP60487.1 - 0.11 12.7 4.7 3.6 7.8 0.8 2.3 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) FAD_binding_2 PF00890.24 OAP60489.1 - 1.1e-58 199.3 0.6 1.4e-58 199.0 0.6 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAP60489.1 - 1.9e-10 40.9 3.3 1.4e-09 38.0 2.4 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAP60489.1 - 5e-08 33.1 0.3 2.2e-07 31.0 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 OAP60489.1 - 1.7e-06 27.5 0.8 9.4e-06 25.1 0.6 1.9 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 OAP60489.1 - 2.5e-06 27.1 0.2 1.2e-05 24.9 0.2 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAP60489.1 - 5.4e-06 25.9 1.2 0.00016 21.0 0.2 2.8 2 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAP60489.1 - 8e-06 26.3 0.2 0.0021 18.6 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAP60489.1 - 1e-05 24.9 0.3 0.001 18.4 0.2 2.5 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.22 OAP60489.1 - 1.9e-05 24.0 0.8 0.0015 17.7 0.0 3.0 2 1 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.14 OAP60489.1 - 0.00028 19.7 0.1 0.014 14.1 0.2 2.4 2 0 0 2 2 2 1 HI0933-like protein Amino_oxidase PF01593.24 OAP60489.1 - 0.003 16.9 0.1 0.019 14.3 0.0 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.21 OAP60489.1 - 0.03 13.6 0.4 0.058 12.7 0.4 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 OAP60489.1 - 0.076 12.3 0.0 1.6 8.0 0.3 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Fis1_TPR_C PF14853.6 OAP60491.1 - 0.1 12.7 0.1 0.21 11.7 0.1 1.5 1 1 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat HET PF06985.11 OAP60492.1 - 8.6e-28 97.5 0.6 1.3e-27 96.9 0.6 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) zf-MYND PF01753.18 OAP60493.1 - 1.5e-07 31.4 8.5 1.5e-07 31.4 8.5 1.8 2 0 0 2 2 2 1 MYND finger SET PF00856.28 OAP60493.1 - 6.4e-06 26.6 0.1 6.2e-05 23.5 0.0 2.6 2 2 0 2 2 2 1 SET domain Alpha-amylase PF00128.24 OAP60494.1 - 1e-37 130.5 0.0 2e-34 119.7 0.0 2.2 2 0 0 2 2 2 2 Alpha amylase, catalytic domain DUF3459 PF11941.8 OAP60494.1 - 0.002 18.4 0.0 0.0047 17.2 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3459) Malt_amylase_C PF16657.5 OAP60494.1 - 0.015 15.4 0.0 0.039 14.1 0.0 1.7 1 0 0 1 1 1 0 Maltogenic Amylase, C-terminal domain hDGE_amylase PF14701.6 OAP60494.1 - 0.036 13.1 0.0 0.061 12.4 0.0 1.3 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain FAS_I_H PF18314.1 OAP60495.1 - 1.8e-80 269.4 0.3 4.4e-80 268.1 0.0 1.8 2 0 0 2 2 2 1 Fatty acid synthase type I helical domain Fas_alpha_ACP PF18325.1 OAP60495.1 - 1.2e-74 250.1 0.0 3.3e-74 248.6 0.0 1.9 1 0 0 1 1 1 1 Fatty acid synthase subunit alpha Acyl carrier domain ketoacyl-synt PF00109.26 OAP60495.1 - 2.6e-22 79.6 0.0 5.3e-22 78.6 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACPS PF01648.20 OAP60495.1 - 6e-18 65.0 0.0 1.7e-17 63.6 0.0 1.8 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.22 OAP60495.1 - 2.5e-11 43.6 0.0 6.5e-11 42.3 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.25 OAP60495.1 - 4.5e-05 23.0 0.0 0.00019 20.9 0.0 2.1 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 OAP60495.1 - 0.0024 17.8 0.0 0.0076 16.2 0.0 1.8 1 0 0 1 1 1 1 KR domain DarA_N PF18788.1 OAP60495.1 - 0.14 12.2 0.0 0.57 10.3 0.0 2.0 1 0 0 1 1 1 0 Defence against restriction A N-terminal BASP1 PF05466.12 OAP60495.1 - 5.3 7.0 17.8 12 5.8 17.8 1.5 1 0 0 1 1 1 0 Brain acid soluble protein 1 (BASP1 protein) DUF1729 PF08354.10 OAP60496.1 - 1.1e-159 531.1 0.0 1.9e-159 530.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) Acyl_transf_1 PF00698.21 OAP60496.1 - 2e-92 310.1 0.0 3.5e-90 302.7 0.0 2.8 3 0 0 3 3 3 1 Acyl transferase domain FAS_meander PF17951.1 OAP60496.1 - 4e-55 185.6 0.1 1.1e-54 184.2 0.0 1.9 2 0 0 2 2 2 1 Fatty acid synthase meander beta sheet domain SAT PF16073.5 OAP60496.1 - 6e-40 137.5 0.1 1.6e-39 136.1 0.0 1.8 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis MaoC_dehydratas PF01575.19 OAP60496.1 - 8.8e-39 131.9 0.0 2e-38 130.7 0.0 1.7 1 0 0 1 1 1 1 MaoC like domain FAS_N PF17828.1 OAP60496.1 - 3.8e-38 130.4 0.0 1.1e-37 128.9 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain in fatty acid synthase subunit beta MaoC_dehydrat_N PF13452.6 OAP60496.1 - 2e-22 79.7 0.0 8.7e-22 77.7 0.0 2.2 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase Peptidase_C39_2 PF13529.6 OAP60498.1 - 0.001 19.6 0.3 0.0023 18.5 0.0 1.7 2 0 0 2 2 2 1 Peptidase_C39 like family Peptidase_C1 PF00112.23 OAP60498.1 - 0.006 16.7 6.6 0.041 14.0 1.4 3.0 2 1 0 2 2 2 1 Papain family cysteine protease DUF5480 PF17576.2 OAP60498.1 - 0.035 14.1 0.1 0.06 13.3 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5480) BtrH_N PF14399.6 OAP60498.1 - 0.086 13.1 0.4 0.19 12.0 0.4 1.6 1 0 0 1 1 1 0 Butirosin biosynthesis protein H, N-terminal DUF1999 PF09390.10 OAP60498.1 - 0.097 12.3 0.1 0.16 11.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1999) Abhydrolase_1 PF00561.20 OAP60499.1 - 1.6e-17 64.0 0.1 4e-17 62.7 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAP60499.1 - 1.2e-12 48.9 0.3 1.4e-12 48.7 0.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAP60499.1 - 3e-06 26.7 0.0 5e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF1057 PF06342.12 OAP60499.1 - 0.011 14.7 0.0 0.11 11.5 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1057) LIDHydrolase PF10230.9 OAP60499.1 - 0.012 15.2 0.0 0.017 14.7 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Urate_ox_N PF06181.11 OAP60499.1 - 0.15 11.4 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 Urate oxidase N-terminal TPR_12 PF13424.6 OAP60500.1 - 1.3e-26 92.7 15.3 2.1e-08 34.3 0.1 6.4 3 2 4 7 7 7 6 Tetratricopeptide repeat TPR_10 PF13374.6 OAP60500.1 - 1.9e-21 75.3 17.2 3.1e-07 30.1 0.5 8.2 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_2 PF07719.17 OAP60500.1 - 3.7e-06 26.6 1.9 10 6.5 0.0 5.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 OAP60500.1 - 0.015 15.1 2.0 4.7 7.2 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 OAP60500.1 - 0.047 14.1 0.8 1.9 9.1 0.0 3.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.14 OAP60500.1 - 0.096 13.4 14.8 31 5.6 0.0 6.8 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_11 PF13414.6 OAP60500.1 - 0.11 12.2 0.1 17 5.2 0.0 3.9 5 0 0 5 5 5 0 TPR repeat TPR_20 PF14561.6 OAP60500.1 - 0.14 12.5 6.7 0.27 11.6 0.8 4.0 2 2 1 3 3 3 0 Tetratricopeptide repeat EIF4E-T PF10477.9 OAP60500.1 - 0.17 10.7 0.0 0.24 10.2 0.0 1.2 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E DUF1841 PF08897.11 OAP60500.1 - 5.9 6.9 7.6 14 5.7 0.1 3.0 3 1 1 4 4 4 0 Domain of unknown function (DUF1841) Fungal_trans_2 PF11951.8 OAP60503.1 - 1.5e-40 139.2 0.2 1.9e-40 138.9 0.2 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Peptidase_M1 PF01433.20 OAP60504.1 - 1.1e-78 263.8 0.3 1.7e-78 263.1 0.3 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 OAP60504.1 - 4.8e-57 193.9 0.0 8.7e-57 193.0 0.0 1.4 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 OAP60504.1 - 5.3e-37 127.8 0.0 4.2e-36 124.9 0.0 2.0 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain TetR_C_28 PF17937.1 OAP60504.1 - 0.068 13.6 0.4 22 5.6 0.0 3.4 2 1 1 3 3 3 0 Tetracyclin repressor-like, C-terminal domain SSXT PF05030.12 OAP60504.1 - 0.12 12.0 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 SSXT protein (N-terminal region) Transp_cyt_pur PF02133.15 OAP60505.1 - 4.1e-103 345.5 34.6 4.8e-103 345.3 34.6 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF917 PF06032.12 OAP60506.1 - 9e-101 337.2 0.2 2.2e-100 335.9 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.18 OAP60506.1 - 3.7e-29 101.9 16.1 2.2e-24 86.2 0.6 3.7 3 1 1 4 4 4 3 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 OAP60506.1 - 8.3e-28 97.3 9.3 5.5e-26 91.3 0.0 3.8 4 0 0 4 4 4 2 Hydantoinase/oxoprolinase N-terminal region MutL PF13941.6 OAP60506.1 - 0.00097 17.8 0.3 0.1 11.2 0.0 2.4 2 0 0 2 2 2 2 MutL protein BcrAD_BadFG PF01869.20 OAP60506.1 - 0.0058 16.2 2.8 0.05 13.1 0.2 2.4 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family FtsA PF14450.6 OAP60506.1 - 0.15 12.4 4.4 3.9 7.9 0.3 3.8 3 0 0 3 3 3 0 Cell division protein FtsA Amidohydro_3 PF07969.11 OAP60507.1 - 0.027 13.9 0.0 0.039 13.4 0.0 1.3 1 0 0 1 1 1 0 Amidohydrolase family Amidohydro_1 PF01979.20 OAP60507.1 - 0.088 12.1 0.1 0.1 11.9 0.1 1.1 1 0 0 1 1 1 0 Amidohydrolase family ATG22 PF11700.8 OAP60509.1 - 2.4e-117 392.5 17.5 2.7e-117 392.3 17.5 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 OAP60509.1 - 1.1e-08 34.4 31.1 1.1e-06 27.9 13.6 3.0 1 1 1 3 3 3 3 Major Facilitator Superfamily SHOCT PF09851.9 OAP60509.1 - 0.00087 18.9 3.0 0.0016 18.1 3.0 1.4 1 0 0 1 1 1 1 Short C-terminal domain Peptidase_S15 PF02129.18 OAP60510.1 - 1.4e-58 198.6 0.1 1.9e-58 198.2 0.1 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 OAP60510.1 - 9.3e-45 153.3 0.0 1.3e-44 152.8 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Abhydrolase_1 PF00561.20 OAP60510.1 - 2.2e-08 34.1 0.1 5.6e-08 32.7 0.1 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAP60510.1 - 1.4e-07 32.4 1.6 1.9e-07 31.9 0.6 1.7 1 1 1 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAP60510.1 - 1.5e-07 30.9 0.0 2.8e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 OAP60510.1 - 8.2e-05 22.2 0.0 0.00018 21.0 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family AXE1 PF05448.12 OAP60510.1 - 0.0028 16.4 0.0 0.0046 15.7 0.0 1.3 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) BAAT_C PF08840.11 OAP60510.1 - 0.23 11.4 0.0 0.39 10.6 0.0 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal 2OG-FeII_Oxy_3 PF13640.6 OAP60511.1 - 0.0091 16.9 0.0 0.017 16.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Fungal_trans_2 PF11951.8 OAP60512.1 - 1.2e-15 57.2 2.0 1.3e-11 44.0 0.1 2.0 1 1 0 2 2 2 2 Fungal specific transcription factor domain Aminotran_1_2 PF00155.21 OAP60513.1 - 6.9e-18 64.9 0.0 9e-18 64.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 OAP60513.1 - 2.8e-07 29.7 0.0 4.1e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase DegT_DnrJ_EryC1 PF01041.17 OAP60513.1 - 0.11 11.8 0.1 0.47 9.7 0.0 1.8 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family AA_permease PF00324.21 OAP60514.1 - 3.1e-102 342.6 38.4 3.8e-102 342.3 38.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAP60514.1 - 4.8e-26 91.6 41.7 6e-26 91.2 41.7 1.0 1 0 0 1 1 1 1 Amino acid permease DUF3671 PF12420.8 OAP60514.1 - 2.2 8.4 7.6 29 4.8 1.2 3.5 3 0 0 3 3 3 0 Protein of unknown function TPP_enzyme_N PF02776.18 OAP60515.1 - 3.4e-32 111.4 0.4 7.6e-32 110.3 0.4 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 OAP60515.1 - 4.8e-17 62.1 0.1 4.1e-16 59.1 0.0 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 OAP60515.1 - 3.5e-14 52.7 0.0 7e-14 51.7 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain DUF4693 PF15764.5 OAP60515.1 - 0.061 12.9 0.0 0.098 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4693) ChlI PF13541.6 OAP60515.1 - 0.12 12.3 0.0 0.45 10.4 0.0 2.0 2 0 0 2 2 2 0 Subunit ChlI of Mg-chelatase HET PF06985.11 OAP60516.1 - 3e-18 66.6 0.0 5.2e-18 65.8 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) AtuA PF07287.11 OAP60517.1 - 2.1e-126 421.4 0.0 2.7e-126 421.0 0.0 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA AtuA PF07287.11 OAP60518.1 - 6.1e-122 406.7 0.1 7.2e-122 406.5 0.1 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA Sec63 PF02889.16 OAP60520.1 - 2.3e-124 413.7 0.0 2.8e-78 262.6 0.3 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 OAP60520.1 - 2.9e-51 173.7 0.1 2.7e-26 92.4 0.6 3.1 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.15 OAP60520.1 - 7.8e-22 78.1 0.0 1.1e-10 41.8 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 OAP60520.1 - 5.9e-15 55.6 0.0 1.3e-06 28.8 0.0 4.5 3 2 0 3 3 3 2 Helicase conserved C-terminal domain AAA_30 PF13604.6 OAP60520.1 - 5e-07 29.6 0.2 0.02 14.6 0.4 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 OAP60520.1 - 8.5e-07 29.3 0.2 0.023 15.0 0.0 3.5 2 1 0 2 2 2 2 AAA domain AAA_19 PF13245.6 OAP60520.1 - 1.5e-06 28.6 1.2 0.00082 19.7 0.9 3.0 3 0 0 3 3 3 1 AAA domain AAA PF00004.29 OAP60520.1 - 0.002 18.6 0.3 4.3 7.8 0.0 4.0 3 2 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) Helicase_PWI PF18149.1 OAP60520.1 - 0.0022 18.1 0.0 0.0064 16.7 0.0 1.7 1 0 0 1 1 1 1 N-terminal helicase PWI domain T2SSE PF00437.20 OAP60520.1 - 0.023 13.8 0.0 1.2 8.1 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein IstB_IS21 PF01695.17 OAP60520.1 - 0.039 13.7 0.2 7.1 6.3 0.0 3.4 4 0 0 4 4 4 0 IstB-like ATP binding protein Radial_spoke_3 PF06098.11 OAP60520.1 - 0.046 13.0 1.4 2.7 7.2 0.9 2.4 2 0 0 2 2 2 0 Radial spoke protein 3 AAA_16 PF13191.6 OAP60520.1 - 0.083 13.3 0.0 4.2 7.7 0.0 2.8 2 0 0 2 2 2 0 AAA ATPase domain Synaptobrevin PF00957.21 OAP60521.1 - 4.2e-14 52.1 0.4 7.2e-14 51.4 0.4 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 OAP60521.1 - 6.3e-10 39.0 0.0 1.1e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Acetyltransf_1 PF00583.25 OAP60522.1 - 6.2e-19 68.4 0.0 8.5e-19 67.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OAP60522.1 - 1.9e-09 37.8 0.0 3.3e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OAP60522.1 - 2.8e-07 30.5 0.0 4.5e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAP60522.1 - 6e-06 26.1 0.0 9.3e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 OAP60522.1 - 7.2e-05 23.5 0.0 0.0001 23.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 OAP60522.1 - 0.0024 18.0 0.0 0.019 15.0 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 OAP60522.1 - 0.01 15.9 0.0 0.02 15.0 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Fungal_trans_2 PF11951.8 OAP60523.1 - 0.004 16.0 0.1 0.18 10.6 0.0 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain TrwB_AAD_bind PF10412.9 OAP60525.1 - 0.013 14.4 0.2 0.036 13.0 0.1 1.7 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain adh_short PF00106.25 OAP60526.1 - 2.2e-33 115.3 0.3 2.8e-33 115.0 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP60526.1 - 8.2e-24 84.4 0.1 1.1e-23 84.1 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 OAP60526.1 - 1.2e-07 31.8 0.0 2e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 OAP60526.1 - 3.8e-06 26.6 0.0 5.2e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 OAP60526.1 - 0.00052 20.3 0.0 0.00079 19.7 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain F420_oxidored PF03807.17 OAP60526.1 - 0.016 15.7 0.0 0.033 14.7 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.21 OAP60526.1 - 0.019 14.4 0.0 0.032 13.7 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAP60526.1 - 0.17 11.2 0.0 0.27 10.6 0.0 1.4 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase Brr6_like_C_C PF10104.9 OAP60527.1 - 1.3e-45 154.5 1.7 1.6e-45 154.1 1.7 1.1 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain DNA_binding_1 PF01035.20 OAP60528.1 - 3.9e-23 81.4 0.0 5.1e-23 81.0 0.0 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain DUF4708 PF15813.5 OAP60529.1 - 0.18 11.0 0.0 0.26 10.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4708) Bud13 PF09736.9 OAP60531.1 - 1.8e-47 161.4 8.3 1.8e-47 161.4 8.3 3.2 2 1 0 2 2 2 1 Pre-mRNA-splicing factor of RES complex HSP70 PF00012.20 OAP60532.1 - 0.0074 14.5 0.0 0.0098 14.1 0.0 1.2 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 OAP60532.1 - 0.021 13.6 0.5 0.13 11.1 0.2 2.1 2 0 0 2 2 2 0 MreB/Mbl protein GIDE PF12483.8 OAP60532.1 - 0.09 12.2 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 E3 Ubiquitin ligase StbA PF06406.11 OAP60532.1 - 0.1 11.8 0.1 0.25 10.6 0.1 1.6 1 0 0 1 1 1 0 StbA protein LapA_dom PF06305.11 OAP60533.1 - 0.024 14.4 0.1 0.052 13.4 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain SKG6 PF08693.10 OAP60533.1 - 0.061 12.8 0.3 0.12 11.8 0.3 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Syndecan PF01034.20 OAP60535.1 - 0.00078 19.3 1.5 0.0009 19.1 0.0 1.9 2 0 0 2 2 2 1 Syndecan domain Herpes_gE PF02480.16 OAP60535.1 - 0.00086 18.2 0.1 0.0014 17.5 0.1 1.3 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E MGC-24 PF05283.11 OAP60535.1 - 0.0086 16.5 11.1 0.16 12.4 11.1 2.2 1 1 0 1 1 1 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin Gly-zipper_Omp PF13488.6 OAP60535.1 - 0.017 15.1 9.2 0.058 13.4 9.2 1.9 1 0 0 1 1 1 0 Glycine zipper Podoplanin PF05808.11 OAP60535.1 - 0.019 15.1 1.1 0.036 14.2 1.1 1.4 1 0 0 1 1 1 0 Podoplanin AJAP1_PANP_C PF15298.6 OAP60535.1 - 0.12 12.6 6.3 0.19 11.9 6.3 1.3 1 0 0 1 1 1 0 AJAP1/PANP C-terminus CoA_transf_3 PF02515.17 OAP60536.1 - 1.4e-95 320.5 0.1 1.8e-95 320.2 0.1 1.1 1 0 0 1 1 1 1 CoA-transferase family III Fungal_trans PF04082.18 OAP60537.1 - 3.8e-10 39.2 0.5 8e-10 38.2 0.2 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain p450 PF00067.22 OAP60538.1 - 9.1e-63 212.6 0.0 1.2e-62 212.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SnoaL_4 PF13577.6 OAP60539.1 - 1.7e-12 47.6 3.0 2.1e-12 47.3 3.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_2 PF12680.7 OAP60539.1 - 2.9e-05 24.6 1.9 4e-05 24.2 1.9 1.3 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 OAP60539.1 - 0.0023 18.3 0.8 0.003 17.9 0.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) FAD_binding_3 PF01494.19 OAP60540.1 - 7.7e-44 150.4 0.0 9.7e-44 150.0 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 OAP60540.1 - 0.00019 20.7 0.2 0.0033 16.5 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 OAP60540.1 - 0.00062 20.0 0.1 0.0031 17.7 0.1 2.2 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 OAP60540.1 - 0.0032 16.7 0.1 0.27 10.3 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 OAP60540.1 - 0.0033 16.2 0.4 0.02 13.6 0.1 1.9 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.24 OAP60540.1 - 0.0099 15.5 1.1 0.022 14.3 0.7 1.8 1 1 1 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 OAP60540.1 - 0.012 14.7 0.0 0.27 10.2 0.1 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox_2 PF07992.14 OAP60540.1 - 0.036 13.3 0.1 0.096 11.9 0.1 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAP60540.1 - 0.041 13.1 0.0 0.078 12.2 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 OAP60540.1 - 0.048 12.9 0.1 0.12 11.6 0.1 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 OAP60540.1 - 0.048 13.0 0.5 0.36 10.1 0.5 2.0 1 1 0 1 1 1 0 FAD dependent oxidoreductase HET PF06985.11 OAP60541.1 - 4.2e-25 88.8 0.0 1.3e-24 87.2 0.0 1.9 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ints3 PF10189.9 OAP60543.1 - 0.06 12.6 0.0 0.091 12.0 0.0 1.2 1 0 0 1 1 1 0 Integrator complex subunit 3 DUF383 PF04063.14 OAP60544.1 - 3.7e-65 219.2 0.0 1.9e-64 216.8 0.0 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF383) DUF384 PF04064.13 OAP60544.1 - 8.9e-23 79.9 3.5 1e-22 79.7 2.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF384) Mic1 PF07035.12 OAP60544.1 - 0.11 12.2 0.2 0.25 11.0 0.2 1.5 1 0 0 1 1 1 0 Colon cancer-associated protein Mic1-like ADSL_C PF10397.9 OAP60544.1 - 0.7 10.5 4.1 0.27 11.8 0.4 2.2 2 1 0 2 2 2 0 Adenylosuccinate lyase C-terminus PI3_PI4_kinase PF00454.27 OAP60545.1 - 5.6e-52 177.0 0.0 1.2e-51 176.0 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 OAP60545.1 - 5.5e-37 127.8 0.7 5e-36 124.6 0.3 2.8 3 0 0 3 3 3 1 FAT domain UME PF08064.13 OAP60545.1 - 1.5e-30 105.1 2.8 4.6e-30 103.5 0.0 3.4 4 0 0 4 4 4 1 UME (NUC010) domain FATC PF02260.20 OAP60545.1 - 3.8e-14 52.2 0.0 1.2e-13 50.7 0.0 1.9 2 0 0 2 2 2 1 FATC domain IFRD PF05004.13 OAP60545.1 - 0.04 13.0 3.0 1.1 8.3 0.5 4.0 5 0 0 5 5 5 0 Interferon-related developmental regulator (IFRD) HEAT_EZ PF13513.6 OAP60545.1 - 0.085 13.4 3.7 6.8 7.3 0.2 4.1 3 0 0 3 3 3 0 HEAT-like repeat TPR_14 PF13428.6 OAP60545.1 - 0.14 13.0 5.0 79 4.5 0.1 5.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 OAP60545.1 - 0.31 11.6 4.5 0.25 11.9 0.2 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Swi3 PF07962.12 OAP60546.1 - 5.9e-30 103.1 0.1 1.2e-29 102.1 0.1 1.6 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 DUF4672 PF15716.5 OAP60546.1 - 0.079 12.6 0.9 0.27 10.8 0.9 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4672) NADH_u_ox_C PF12853.7 OAP60547.1 - 8.3e-25 86.6 0.1 1.6e-24 85.7 0.1 1.4 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit NADH-u_ox-rdase PF10785.9 OAP60547.1 - 1.3e-21 77.0 0.2 2.3e-21 76.3 0.2 1.4 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit Rop-like PF05082.13 OAP60547.1 - 0.013 15.3 0.1 0.052 13.4 0.1 2.0 1 0 0 1 1 1 0 Rop-like Trigger_N PF05697.13 OAP60549.1 - 0.093 13.1 0.0 0.26 11.6 0.0 1.7 1 0 0 1 1 1 0 Bacterial trigger factor protein (TF) Lipoprotein_22 PF17294.2 OAP60549.1 - 0.094 12.4 0.0 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised lipoprotein family Sec3_C_2 PF15278.6 OAP60549.1 - 0.19 12.1 1.1 30 5.0 0.0 3.3 3 0 0 3 3 3 0 Sec3 exocyst complex subunit PRKCSH-like PF12999.7 OAP60550.1 - 2.8e-47 160.8 2.8 6.1e-26 91.3 0.6 2.6 2 0 0 2 2 2 2 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 OAP60550.1 - 4.3e-33 114.2 0.6 2e-32 112.0 0.1 2.1 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 OAP60550.1 - 9e-11 42.6 0.2 2.3e-10 41.3 0.2 1.8 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein ATG27 PF09451.10 OAP60550.1 - 0.02 14.8 0.3 0.04 13.8 0.3 1.5 1 0 0 1 1 1 0 Autophagy-related protein 27 Uds1 PF15456.6 OAP60550.1 - 0.081 13.1 10.0 0.1 12.8 3.0 2.7 2 1 1 3 3 3 0 Up-regulated During Septation CdAMP_rec PF06153.11 OAP60550.1 - 0.092 13.0 0.1 0.19 11.9 0.1 1.5 1 0 0 1 1 1 0 Cyclic-di-AMP receptor DNA_pol3_beta_3 PF02768.15 OAP60550.1 - 0.6 10.0 3.4 1.2 9.0 3.4 1.4 1 0 0 1 1 1 0 DNA polymerase III beta subunit, C-terminal domain MutS_IV PF05190.18 OAP60550.1 - 1.4 9.4 4.3 3.6 8.0 0.4 2.9 3 0 0 3 3 3 0 MutS family domain IV Tropomyosin PF00261.20 OAP60550.1 - 1.5 8.1 21.0 0.053 12.9 7.2 3.1 3 0 0 3 3 3 0 Tropomyosin Snapin_Pallidin PF14712.6 OAP60550.1 - 2.3 8.7 9.5 3 8.3 0.0 2.6 3 0 0 3 3 3 0 Snapin/Pallidin Ldl_recept_a PF00057.18 OAP60550.1 - 4 7.8 13.6 0.2 11.9 1.8 2.7 2 0 0 2 2 2 0 Low-density lipoprotein receptor domain class A BST2 PF16716.5 OAP60550.1 - 9 7.0 10.8 1.1 10.0 0.1 3.0 3 0 0 3 3 3 0 Bone marrow stromal antigen 2 F-box-like PF12937.7 OAP60551.1 - 0.0044 16.9 1.0 0.033 14.1 0.0 2.8 3 0 0 3 3 3 1 F-box-like Fungal_TACC PF12709.7 OAP60552.1 - 2.1e-08 34.5 6.1 2.1e-08 34.5 6.1 4.0 3 2 0 3 3 3 2 Fungal Transforming acidic coiled-coil (TACC) proteins DUF4685 PF15737.5 OAP60552.1 - 0.02 15.3 3.5 1.2 9.6 0.2 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4685) CT_C_D PF02682.16 OAP60552.1 - 0.094 12.4 0.1 0.26 11.0 0.1 1.8 1 1 0 1 1 1 0 Carboxyltransferase domain, subdomain C and D DUF4407 PF14362.6 OAP60552.1 - 0.21 10.9 21.6 1.7 7.9 6.6 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Spc7 PF08317.11 OAP60552.1 - 1.5 7.6 35.2 0.037 12.9 13.7 2.5 2 1 0 2 2 2 0 Spc7 kinetochore protein DUF5082 PF16888.5 OAP60552.1 - 2 8.7 16.7 0.92 9.8 5.6 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) JIP_LZII PF16471.5 OAP60552.1 - 5.9 7.1 25.5 0.26 11.5 2.9 4.4 3 1 0 4 4 4 0 JNK-interacting protein leucine zipper II SWI-SNF_Ssr4 PF08549.10 OAP60553.1 - 5.8 5.4 6.3 7.8 5.0 6.3 1.2 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Lyase_1 PF00206.20 OAP60554.1 - 1.8e-39 136.0 0.0 2.9e-39 135.3 0.0 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 OAP60554.1 - 4.1e-20 72.1 0.1 1.1e-19 70.8 0.1 1.8 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus Crp PF00325.20 OAP60554.1 - 0.095 12.4 0.0 1.6 8.5 0.0 2.6 1 1 0 1 1 1 0 Bacterial regulatory proteins, crp family GST_C_3 PF14497.6 OAP60555.1 - 6.5e-31 106.5 0.0 1.5e-30 105.3 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OAP60555.1 - 2.5e-06 27.6 0.0 4.3e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain ADH_zinc_N PF00107.26 OAP60556.1 - 6e-09 36.0 0.0 9e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAP60556.1 - 0.00054 21.0 0.0 0.001 20.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAP60556.1 - 0.015 15.1 0.2 0.038 13.9 0.1 1.7 2 0 0 2 2 2 0 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 OAP60556.1 - 0.044 13.7 0.0 1.3 9.0 0.0 2.5 2 0 0 2 2 2 0 N-terminal domain of oxidoreductase RST PF12174.8 OAP60556.1 - 0.087 12.8 0.1 0.22 11.5 0.1 1.6 1 0 0 1 1 1 0 RCD1-SRO-TAF4 (RST) plant domain HC2 PF07382.11 OAP60557.1 - 3.1e-05 24.1 13.9 3.1e-05 24.1 13.9 1.6 2 0 0 2 2 2 1 Histone H1-like nucleoprotein HC2 Microvir_lysis PF04517.12 OAP60557.1 - 0.012 15.5 0.6 0.012 15.5 0.6 1.8 2 0 0 2 2 2 0 Microvirus lysis protein (E), C terminus Glyco_hydro_127 PF07944.12 OAP60558.1 - 5.5e-103 345.2 0.0 6.9e-103 344.9 0.0 1.0 1 0 0 1 1 1 1 Beta-L-arabinofuranosidase, GH127 MFS_1 PF07690.16 OAP60559.1 - 7.9e-09 34.9 23.9 7.9e-09 34.9 23.9 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 OAP60559.1 - 1.9e-05 24.4 2.6 1.9e-05 24.4 2.6 2.5 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 Bac_luciferase PF00296.20 OAP60560.1 - 6.7e-55 186.7 4.0 1.1e-54 186.0 4.0 1.2 1 0 0 1 1 1 1 Luciferase-like monooxygenase MFS_1 PF07690.16 OAP60561.1 - 2.5e-34 118.8 35.2 2.5e-34 118.8 35.2 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily adh_short PF00106.25 OAP60562.1 - 1.9e-20 73.1 0.1 1.1e-15 57.6 0.2 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAP60562.1 - 3.9e-13 49.5 0.0 3.6e-10 39.8 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP60562.1 - 0.001 19.0 0.4 0.0017 18.3 0.4 1.2 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 OAP60562.1 - 0.084 13.1 0.2 0.14 12.4 0.2 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain FAD_binding_3 PF01494.19 OAP60563.1 - 4.1e-12 46.0 0.7 2.4e-06 27.1 0.0 2.9 2 1 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 OAP60563.1 - 2.9e-07 30.0 0.2 0.00031 20.1 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAP60563.1 - 3.2e-06 26.5 0.1 5.2e-06 25.8 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 OAP60563.1 - 1.5e-05 25.1 0.1 4.4e-05 23.6 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 OAP60563.1 - 0.00029 20.3 0.1 0.00093 18.6 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 OAP60563.1 - 0.00039 19.2 0.0 0.0016 17.2 0.0 1.8 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 OAP60563.1 - 0.0006 19.0 0.1 0.00096 18.3 0.1 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.27 OAP60563.1 - 0.0032 18.0 0.2 0.17 12.5 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAP60563.1 - 0.036 13.3 0.0 0.16 11.2 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAP60563.1 - 0.041 13.5 0.6 0.089 12.4 0.3 1.7 1 1 0 1 1 1 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 OAP60563.1 - 0.042 13.1 0.0 0.074 12.3 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Sulfotransfer_4 PF17784.1 OAP60563.1 - 0.15 11.9 0.3 0.71 9.7 0.0 2.1 2 0 0 2 2 2 0 Sulfotransferase domain XPG_I_2 PF12813.7 OAP60564.1 - 1.9e-48 165.1 0.0 2.6e-48 164.7 0.0 1.2 1 0 0 1 1 1 1 XPG domain containing XPG_I PF00867.18 OAP60564.1 - 0.022 15.1 0.0 0.048 14.0 0.0 1.5 1 0 0 1 1 1 0 XPG I-region DUF4851 PF16143.5 OAP60564.1 - 0.034 13.6 0.0 0.061 12.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4851) NAD_binding_4 PF07993.12 OAP60565.1 - 5.1e-41 140.6 0.0 9.9e-41 139.6 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 OAP60565.1 - 9.1e-33 113.5 0.0 4.7e-32 111.1 0.0 1.9 2 0 0 2 2 2 1 AMP-binding enzyme Epimerase PF01370.21 OAP60565.1 - 2.7e-10 40.2 0.0 5.7e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 OAP60565.1 - 1.8e-09 37.8 0.0 4.7e-09 36.5 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site AAA_33 PF13671.6 OAP60565.1 - 1.3e-07 31.9 1.3 9.5e-07 29.1 0.1 2.9 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 OAP60565.1 - 1.1e-06 29.2 2.0 1.2e-05 25.8 1.1 3.6 3 1 0 3 3 2 1 AAA domain AAA_16 PF13191.6 OAP60565.1 - 0.00029 21.3 0.0 0.0011 19.4 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain KR PF08659.10 OAP60565.1 - 0.00037 20.4 0.0 0.0015 18.5 0.0 2.1 1 0 0 1 1 1 1 KR domain SKI PF01202.22 OAP60565.1 - 0.00041 20.5 0.3 1.2 9.3 0.0 3.0 3 0 0 3 3 2 2 Shikimate kinase Cytidylate_kin PF02224.18 OAP60565.1 - 0.00046 20.0 0.0 0.0022 17.8 0.0 2.2 2 0 0 2 2 2 1 Cytidylate kinase NACHT PF05729.12 OAP60565.1 - 0.00049 20.1 0.3 0.41 10.6 0.0 3.6 4 0 0 4 4 3 1 NACHT domain 3Beta_HSD PF01073.19 OAP60565.1 - 0.00069 18.7 0.0 0.0053 15.8 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 OAP60565.1 - 0.012 15.0 0.0 0.14 11.5 0.0 2.1 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Ploopntkinase3 PF18751.1 OAP60565.1 - 0.018 14.9 0.0 1.4 8.8 0.0 2.5 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 Polysacc_synt_2 PF02719.15 OAP60565.1 - 0.023 13.8 0.0 0.042 13.0 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NmrA PF05368.13 OAP60565.1 - 0.024 14.2 0.1 0.046 13.3 0.1 1.4 1 0 0 1 1 1 0 NmrA-like family AAA_22 PF13401.6 OAP60565.1 - 0.028 14.7 0.3 0.67 10.2 0.0 3.2 4 0 0 4 4 3 0 AAA domain NAD_binding_10 PF13460.6 OAP60565.1 - 0.04 13.8 0.1 0.12 12.3 0.1 1.8 1 0 0 1 1 1 0 NAD(P)H-binding AAA PF00004.29 OAP60565.1 - 0.046 14.2 0.2 0.19 12.2 0.0 2.1 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 OAP60565.1 - 0.051 14.0 0.1 0.22 12.0 0.1 2.1 1 1 0 1 1 1 0 AAA domain dNK PF01712.19 OAP60565.1 - 0.069 13.0 0.0 0.94 9.3 0.0 2.3 2 0 0 2 2 2 0 Deoxynucleoside kinase RsgA_GTPase PF03193.16 OAP60565.1 - 0.078 12.9 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase ParA PF10609.9 OAP60565.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase RNA_helicase PF00910.22 OAP60565.1 - 0.17 12.2 0.0 0.47 10.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Fungal_trans PF04082.18 OAP60567.1 - 1.9e-26 92.7 0.3 3e-26 92.1 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP60567.1 - 2.9e-06 27.3 5.8 5.6e-06 26.4 5.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldo_ket_red PF00248.21 OAP60568.1 - 2.7e-51 174.5 0.0 1.2e-50 172.4 0.0 1.8 1 1 0 1 1 1 1 Aldo/keto reductase family HlyIII PF03006.20 OAP60569.1 - 1.5e-51 175.3 16.2 1.8e-51 175.0 16.2 1.1 1 0 0 1 1 1 1 Haemolysin-III related SnAC PF14619.6 OAP60569.1 - 0.036 14.7 0.0 0.056 14.1 0.0 1.2 1 0 0 1 1 1 0 Snf2-ATP coupling, chromatin remodelling complex MaoC_dehydratas PF01575.19 OAP60570.1 - 2e-10 40.3 0.0 3.3e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain DUF3581 PF12119.8 OAP60570.1 - 0.18 11.2 0.1 0.54 9.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3581) RibD_C PF01872.17 OAP60571.1 - 3.6e-28 98.8 0.0 7.6e-28 97.7 0.0 1.6 1 1 0 1 1 1 1 RibD C-terminal domain RRM_1 PF00076.22 OAP60572.1 - 4.4e-13 48.9 0.0 6.3e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OAP60572.1 - 0.19 11.8 0.0 0.35 11.0 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif PYRIN PF02758.16 OAP60572.1 - 0.21 11.7 0.0 0.4 10.9 0.0 1.4 1 0 0 1 1 1 0 PAAD/DAPIN/Pyrin domain Glyco_hydro_79C PF16862.5 OAP60573.1 - 3.1e-24 85.8 1.6 2e-23 83.2 0.3 2.7 3 0 0 3 3 3 1 Glycosyl hydrolase family 79 C-terminal beta domain Kinesin PF00225.23 OAP60574.1 - 1.8e-27 96.1 0.1 1.5e-20 73.4 0.0 2.1 2 0 0 2 2 2 2 Kinesin motor domain AMP-binding PF00501.28 OAP60575.1 - 3.7e-88 296.0 0.0 5.5e-88 295.4 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAP60575.1 - 1.5e-12 48.3 0.2 5e-12 46.6 0.2 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Zn_clus PF00172.18 OAP60575.1 - 3.4e-06 27.1 4.7 6.2e-06 26.2 4.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2201 PF09967.9 OAP60575.1 - 0.064 13.4 0.1 0.14 12.3 0.1 1.5 1 0 0 1 1 1 0 VWA-like domain (DUF2201) DSBA PF01323.20 OAP60576.1 - 1e-18 67.8 0.0 1.2e-18 67.6 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Oxidored_molyb PF00174.19 OAP60577.1 - 3.8e-43 147.1 0.0 5.6e-43 146.5 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 OAP60577.1 - 1e-07 32.1 0.0 2.1e-07 31.0 0.0 1.5 1 1 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Big_7 PF17957.1 OAP60577.1 - 0.00011 22.9 0.0 0.0013 19.4 0.0 2.3 1 1 1 2 2 2 1 Bacterial Ig domain Gmad2 PF10648.9 OAP60577.1 - 0.01 16.1 0.0 0.021 15.1 0.0 1.5 1 0 0 1 1 1 0 Immunoglobulin-like domain of bacterial spore germination Y_Y_Y PF07495.13 OAP60577.1 - 0.13 12.2 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 Y_Y_Y domain Fungal_trans PF04082.18 OAP60578.1 - 5.7e-11 41.9 0.2 9.6e-11 41.2 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP60578.1 - 3.8e-06 26.9 11.0 6.6e-06 26.1 11.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PEP_mutase PF13714.6 OAP60579.1 - 1.8e-49 168.3 0.3 2.1e-49 168.1 0.3 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 OAP60579.1 - 1.1e-20 73.7 0.3 1.4e-20 73.3 0.3 1.1 1 0 0 1 1 1 1 Isocitrate lyase family Pantoate_transf PF02548.15 OAP60579.1 - 0.0042 16.5 0.0 0.012 15.0 0.0 1.8 1 1 0 1 1 1 1 Ketopantoate hydroxymethyltransferase Bep_C_terminal PF17841.1 OAP60579.1 - 0.099 12.9 0.1 0.25 11.6 0.0 1.6 2 0 0 2 2 2 0 BID domain of Bartonella effector protein (Bep) AMP-binding PF00501.28 OAP60580.1 - 8.6e-79 265.1 0.1 1.1e-78 264.7 0.1 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAP60580.1 - 7.5e-17 62.1 0.4 3.1e-16 60.1 0.1 2.3 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain PIP5K PF01504.18 OAP60581.1 - 1.2e-45 155.9 0.0 5.8e-45 153.6 0.0 1.8 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Oxysterol_BP PF01237.18 OAP60582.1 - 3.3e-49 167.7 0.0 7.9e-46 156.6 0.0 3.2 1 1 0 1 1 1 1 Oxysterol-binding protein TMEM171 PF15471.6 OAP60582.1 - 0.13 11.2 2.2 0.24 10.3 2.2 1.3 1 0 0 1 1 1 0 Transmembrane protein family 171 Zn_clus PF00172.18 OAP60583.1 - 1.9e-08 34.3 11.4 3.4e-08 33.5 11.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAP60583.1 - 0.0021 17.1 0.2 0.0038 16.3 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF1712 PF08217.11 OAP60584.1 - 1.8e-14 53.2 0.0 7.3e-12 44.6 0.0 2.2 2 0 0 2 2 2 2 Fungal domain of unknown function (DUF1712) Ras PF00071.22 OAP60585.1 - 2.9e-57 192.8 0.0 3.3e-57 192.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAP60585.1 - 3.1e-22 79.0 0.0 4.7e-22 78.5 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAP60585.1 - 2.2e-06 27.2 0.0 3.6e-06 26.6 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 OAP60585.1 - 0.0077 15.7 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit NB-ARC PF00931.22 OAP60585.1 - 0.046 12.9 0.1 0.43 9.7 0.0 2.0 1 1 1 2 2 2 0 NB-ARC domain Gtr1_RagA PF04670.12 OAP60585.1 - 0.14 11.5 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Abhydrolase_6 PF12697.7 OAP60586.1 - 4.7e-19 69.9 0.0 5.6e-19 69.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 OAP60586.1 - 0.0051 16.4 0.0 1.1 8.7 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family Hydrolase_4 PF12146.8 OAP60586.1 - 0.013 14.8 0.0 0.1 11.8 0.0 2.2 1 1 0 1 1 1 0 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 OAP60586.1 - 0.016 14.1 0.0 0.022 13.7 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Abhydrolase_1 PF00561.20 OAP60586.1 - 0.087 12.5 0.0 0.19 11.3 0.0 1.6 2 0 0 2 2 2 0 alpha/beta hydrolase fold E1-E2_ATPase PF00122.20 OAP60587.1 - 1.5e-38 132.1 0.2 1.5e-38 132.1 0.2 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 OAP60587.1 - 6.3e-36 123.8 5.6 6.3e-36 123.8 5.6 2.4 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 OAP60587.1 - 3.2e-21 76.6 0.0 1.2e-10 42.1 0.1 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 OAP60587.1 - 5.4e-11 42.4 0.0 1e-10 41.5 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 OAP60587.1 - 7.4e-09 35.2 0.0 1.7e-08 34.0 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.7 OAP60587.1 - 0.0013 19.1 0.0 0.0061 17.0 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2231 PF09990.9 OAP60587.1 - 0.8 10.2 7.6 0.071 13.6 0.5 2.7 3 0 0 3 3 3 0 Predicted membrane protein (DUF2231) HET PF06985.11 OAP60588.1 - 9.1e-27 94.2 0.1 1.4e-26 93.6 0.1 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ZZ PF00569.17 OAP60588.1 - 0.0027 17.5 9.6 0.0056 16.5 9.6 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type zf-UDP PF14569.6 OAP60588.1 - 0.1 12.8 3.2 0.23 11.6 3.2 1.7 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-UBR PF02207.20 OAP60588.1 - 0.33 11.1 6.7 0.22 11.7 4.1 2.1 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) DUF805 PF05656.14 OAP60589.1 - 1.1 9.7 6.3 7.5 7.0 6.3 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF805) MARVEL PF01284.23 OAP60589.1 - 1.1 9.3 6.4 0.23 11.5 1.8 2.1 2 1 0 2 2 2 0 Membrane-associating domain PhoD PF09423.10 OAP60590.1 - 1.3e-06 27.7 0.2 0.0004 19.5 0.2 2.9 2 1 0 2 2 2 2 PhoD-like phosphatase Rad51 PF08423.11 OAP60591.1 - 4e-128 426.0 0.0 4.9e-128 425.8 0.0 1.1 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 OAP60591.1 - 1.2e-10 41.4 0.0 1.5e-10 41.0 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.6 OAP60591.1 - 2.6e-09 36.9 0.0 3.7e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 OAP60591.1 - 1.6e-05 24.4 0.1 3.3e-05 23.3 0.1 1.5 1 1 0 1 1 1 1 KaiC HHH_5 PF14520.6 OAP60591.1 - 2.3e-05 24.9 0.3 8.9e-05 23.0 0.1 2.1 3 0 0 3 3 3 1 Helix-hairpin-helix domain DnaB_C PF03796.15 OAP60591.1 - 0.0086 15.4 0.2 0.081 12.2 0.0 2.0 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain AAA_22 PF13401.6 OAP60591.1 - 0.03 14.6 0.2 0.085 13.1 0.2 1.7 1 1 0 1 1 1 0 AAA domain PAXNEB PF05625.11 OAP60591.1 - 0.078 12.1 2.2 0.47 9.5 0.5 2.1 1 1 1 2 2 2 0 PAXNEB protein AAA_24 PF13479.6 OAP60591.1 - 0.14 11.8 0.0 0.33 10.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain Transferase PF02458.15 OAP60592.1 - 2.6e-23 82.4 0.0 2.8e-17 62.5 0.0 2.8 2 1 0 2 2 2 2 Transferase family PXA PF02194.15 OAP60593.1 - 4e-49 167.1 2.8 7.2e-49 166.2 0.7 2.5 2 1 1 3 3 3 1 PXA domain Nexin_C PF08628.12 OAP60593.1 - 6e-24 84.8 0.2 6.5e-23 81.5 0.1 2.7 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.24 OAP60593.1 - 2.3e-21 75.9 1.2 6.2e-21 74.5 0.6 2.1 2 0 0 2 2 2 1 PX domain RGS PF00615.19 OAP60593.1 - 3.3e-12 46.7 0.1 1.1e-11 45.0 0.1 2.0 1 0 0 1 1 1 1 Regulator of G protein signaling domain RRP36 PF06102.12 OAP60593.1 - 0.063 13.2 0.1 0.063 13.2 0.1 2.8 3 0 0 3 3 3 0 rRNA biogenesis protein RRP36 CPDase PF07823.11 OAP60593.1 - 0.11 12.2 0.0 0.92 9.2 0.0 2.2 2 0 0 2 2 2 0 Cyclic phosphodiesterase-like protein HD_assoc PF13286.6 OAP60593.1 - 0.12 12.9 0.4 4.3 7.9 0.0 3.2 1 1 1 2 2 2 0 Phosphohydrolase-associated domain FMO-like PF00743.19 OAP60594.1 - 1.2e-09 37.2 0.0 2.5e-08 32.8 0.0 2.2 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OAP60594.1 - 2.1e-09 37.5 0.0 5.2e-09 36.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 OAP60594.1 - 1.1e-06 28.1 0.0 0.026 13.8 0.0 3.7 4 1 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAP60594.1 - 9.7e-06 24.9 0.1 0.0021 17.3 0.0 3.4 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 OAP60594.1 - 0.034 14.2 0.0 0.15 12.0 0.0 2.2 3 0 0 3 3 3 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 OAP60594.1 - 0.1 11.8 0.0 1.7 7.8 0.0 2.6 3 1 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Cupin_8 PF13621.6 OAP60595.1 - 3.2e-25 89.3 0.0 3.5e-25 89.2 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 OAP60595.1 - 0.007 15.9 0.0 0.016 14.7 0.0 1.5 2 0 0 2 2 2 1 Cupin superfamily protein JmjC PF02373.22 OAP60595.1 - 0.018 15.4 0.0 0.14 12.5 0.0 2.3 3 0 0 3 3 3 0 JmjC domain, hydroxylase DUF3701 PF12482.8 OAP60595.1 - 0.028 14.5 0.5 0.05 13.7 0.5 1.4 1 0 0 1 1 1 0 Phage integrase protein Cupin_2 PF07883.11 OAP60595.1 - 0.06 13.1 0.0 0.22 11.2 0.0 2.0 2 0 0 2 2 2 0 Cupin domain CK_II_beta PF01214.18 OAP60596.1 - 2.8e-76 255.4 0.0 7.6e-76 254.0 0.0 1.7 1 1 0 1 1 1 1 Casein kinase II regulatory subunit Spt5_N PF11942.8 OAP60596.1 - 0.015 16.2 17.5 0.38 11.8 0.7 2.6 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Fungal_trans PF04082.18 OAP60597.1 - 1.5e-15 56.9 0.0 2.5e-15 56.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP60597.1 - 2.5e-05 24.3 6.5 4.6e-05 23.5 6.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Helo_like_N PF17111.5 OAP60597.1 - 0.1 12.0 0.0 4.3 6.7 0.0 2.4 2 0 0 2 2 2 0 Fungal N-terminal domain of STAND proteins HalX PF08663.10 OAP60597.1 - 0.17 12.2 0.4 0.4 11.0 0.4 1.6 1 0 0 1 1 1 0 HalX domain CIA30 PF08547.12 OAP60598.1 - 9.5e-26 90.7 0.0 1.8e-25 89.8 0.0 1.4 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) bZIP_1 PF00170.21 OAP60598.1 - 0.00036 20.6 5.5 0.0006 19.9 5.5 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 OAP60598.1 - 0.0079 16.3 6.7 0.013 15.6 6.7 1.3 1 0 0 1 1 1 1 Basic region leucine zipper UPF0561 PF10573.9 OAP60598.1 - 0.014 15.5 2.5 0.026 14.7 2.5 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0561 bZIP_Maf PF03131.17 OAP60598.1 - 0.33 11.5 6.6 0.61 10.6 6.6 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor PknG_rubred PF16919.5 OAP60599.1 - 0.00066 19.9 0.4 0.00098 19.3 0.1 1.5 2 0 0 2 2 2 1 Protein kinase G rubredoxin domain DUF4123 PF13503.6 OAP60599.1 - 0.003 18.0 0.0 0.0034 17.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4123) DEAD PF00270.29 OAP60601.1 - 1e-51 175.2 0.0 2.6e-50 170.6 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAP60601.1 - 5.3e-27 94.4 0.0 2e-26 92.5 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAP60601.1 - 0.0036 17.3 0.0 0.023 14.7 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 OAP60601.1 - 0.14 11.4 1.2 0.72 9.1 0.0 2.5 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit HMG_box_2 PF09011.10 OAP60602.1 - 2.7e-13 50.3 12.5 3.2e-11 43.7 0.3 3.3 2 1 0 2 2 2 2 HMG-box domain HMG_box PF00505.19 OAP60602.1 - 3e-13 50.0 12.1 9.6e-10 38.7 1.8 3.3 2 1 0 2 2 2 2 HMG (high mobility group) box Ribosomal_L10 PF00466.20 OAP60603.1 - 0.0042 17.2 0.0 0.027 14.6 0.0 2.1 1 1 0 1 1 1 1 Ribosomal protein L10 Ntox1 PF15500.6 OAP60603.1 - 0.087 13.2 0.0 0.16 12.4 0.0 1.3 1 0 0 1 1 1 0 Putative RNase-like toxin, toxin_1 SSF PF00474.17 OAP60604.1 - 1.7e-17 63.4 31.9 2.6e-17 62.8 31.9 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family Pilt PF15453.6 OAP60604.1 - 0.9 8.9 7.0 1.5 8.2 7.0 1.2 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions p450 PF00067.22 OAP60605.1 - 2.3e-72 244.2 0.0 2.8e-72 243.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HTH_27 PF13463.6 OAP60605.1 - 0.07 13.6 0.0 0.14 12.7 0.0 1.5 1 0 0 1 1 1 0 Winged helix DNA-binding domain Methyltransf_25 PF13649.6 OAP60606.1 - 4.2e-17 62.6 0.0 7.2e-17 61.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAP60606.1 - 1.8e-15 57.3 0.0 4.9e-15 55.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAP60606.1 - 6.3e-10 39.1 0.0 9.2e-10 38.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAP60606.1 - 1e-09 38.4 0.0 1.4e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAP60606.1 - 1.7e-06 28.7 0.0 3.1e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OAP60606.1 - 2.7e-06 27.0 0.0 4.2e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain tRNA_U5-meth_tr PF05958.11 OAP60606.1 - 5.7e-05 22.3 0.0 7.5e-05 21.9 0.0 1.1 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Ubie_methyltran PF01209.18 OAP60606.1 - 0.00016 21.1 0.0 0.0023 17.3 0.0 2.0 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family NodS PF05401.11 OAP60606.1 - 0.00039 20.1 0.0 0.00045 19.9 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_15 PF09445.10 OAP60606.1 - 0.02 14.5 0.1 0.05 13.2 0.0 1.6 1 1 1 2 2 2 0 RNA cap guanine-N2 methyltransferase UPF0146 PF03686.13 OAP60606.1 - 0.02 14.7 0.0 0.032 14.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) PrmA PF06325.13 OAP60606.1 - 0.021 14.2 0.0 0.025 14.0 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) TehB PF03848.14 OAP60606.1 - 0.042 13.3 0.0 0.063 12.7 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_18 PF12847.7 OAP60606.1 - 0.089 12.7 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain CheR PF01739.18 OAP60606.1 - 0.093 12.2 0.0 5.2 6.5 0.0 2.5 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain Methyltransf_16 PF10294.9 OAP60606.1 - 0.15 11.7 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase CMAS PF02353.20 OAP60606.1 - 0.18 11.1 0.0 0.2 10.9 0.0 1.3 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase MFS_1 PF07690.16 OAP60607.1 - 4.6e-20 71.8 43.3 2.3e-18 66.3 36.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAP60607.1 - 9.8e-06 24.7 8.6 9.8e-06 24.7 8.6 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter 2OG-FeII_Oxy_3 PF13640.6 OAP60608.1 - 1.2e-09 38.9 0.1 2e-09 38.2 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily adh_short PF00106.25 OAP60609.1 - 7.2e-32 110.4 0.0 2.5e-31 108.6 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP60609.1 - 2.4e-27 96.0 0.0 6.2e-27 94.7 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP60609.1 - 1.2e-05 25.3 0.0 0.0068 16.3 0.0 2.2 2 0 0 2 2 2 2 KR domain adh_short PF00106.25 OAP60610.1 - 7.2e-42 143.1 0.1 9.4e-42 142.7 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP60610.1 - 3.3e-35 121.7 0.1 5.2e-35 121.1 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP60610.1 - 4.9e-08 33.1 0.0 9.7e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAP60610.1 - 0.00011 21.7 0.0 0.00019 21.0 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 OAP60610.1 - 0.073 12.9 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AMP-binding PF00501.28 OAP60611.1 - 4.7e-67 226.4 0.0 5.6e-67 226.2 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAP60611.1 - 2.9e-18 66.6 0.1 6.4e-18 65.5 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PUA_3 PF17785.1 OAP60611.1 - 0.031 14.1 0.1 0.11 12.4 0.1 2.0 1 1 0 1 1 1 0 PUA-like domain Ins134_P3_kin_N PF17927.1 OAP60611.1 - 0.17 12.3 0.0 1.1 9.8 0.0 2.2 2 0 0 2 2 2 0 Inositol 1,3,4-trisphosphate 5/6-kinase pre-ATP-grasp domain LRR_4 PF12799.7 OAP60612.1 - 3.1e-10 40.1 14.7 1.2 9.6 0.3 7.5 6 1 1 7 7 7 5 Leucine Rich repeats (2 copies) F-box-like PF12937.7 OAP60612.1 - 2e-09 37.2 0.8 7.3e-09 35.4 0.8 2.1 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.6 OAP60612.1 - 3.6e-05 23.5 26.2 3.1 8.1 0.1 10.8 12 0 0 12 12 12 3 Leucine Rich repeat F-box PF00646.33 OAP60612.1 - 4e-05 23.4 0.2 0.00017 21.4 0.2 2.2 1 0 0 1 1 1 1 F-box domain Glyco_hydro_15 PF00723.21 OAP60614.1 - 0.033 13.0 0.4 0.051 12.3 0.4 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 15 TPR_12 PF13424.6 OAP60614.1 - 0.14 12.5 0.0 6.5 7.1 0.2 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Ribosomal_L11_N PF03946.14 OAP60614.1 - 0.2 11.5 0.2 0.38 10.6 0.2 1.4 1 0 0 1 1 1 0 Ribosomal protein L11, N-terminal domain MFS_1 PF07690.16 OAP60615.1 - 2.7e-19 69.3 53.5 2.2e-18 66.3 29.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Ribosomal_L1 PF00687.21 OAP60618.1 - 7.9e-47 159.6 0.2 9e-47 159.5 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Acetyltransf_7 PF13508.7 OAP60619.1 - 2.8e-11 43.7 0.0 4.1e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAP60619.1 - 6.7e-11 42.5 0.0 1e-10 41.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 OAP60619.1 - 5.9e-10 39.0 0.0 1.4e-09 37.7 0.0 1.6 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 OAP60619.1 - 4.4e-09 36.3 0.0 8.8e-09 35.4 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 OAP60619.1 - 7.4e-06 26.0 0.0 1.4e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.7 OAP60619.1 - 0.0011 19.7 0.0 0.0014 19.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 OAP60619.1 - 0.0032 17.2 0.0 0.0048 16.6 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 OAP60619.1 - 0.097 12.8 0.0 0.18 11.9 0.0 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Arf PF00025.21 OAP60620.1 - 6.6e-80 266.7 0.1 7.7e-80 266.4 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 OAP60620.1 - 3e-14 53.2 0.0 4.3e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 OAP60620.1 - 5.1e-14 52.1 0.0 6.2e-14 51.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 OAP60620.1 - 2.5e-13 49.9 1.4 2e-09 37.1 0.3 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 OAP60620.1 - 8.2e-13 48.3 0.0 8.9e-13 48.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 OAP60620.1 - 1.7e-10 40.7 0.0 2.1e-10 40.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OAP60620.1 - 4.1e-06 26.8 0.0 6.4e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 OAP60620.1 - 0.011 15.1 0.7 0.026 13.8 0.7 1.7 1 1 0 1 1 1 0 6-phosphofructo-2-kinase Aconitase PF00330.20 OAP60621.1 - 2.6e-93 313.5 0.0 9.9e-90 301.7 0.0 2.9 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 OAP60621.1 - 6.7e-21 75.0 0.0 1.2e-20 74.1 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF2686 PF10887.8 OAP60621.1 - 0.0006 18.9 0.1 0.0011 18.0 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2686) WH2 PF02205.20 OAP60622.1 - 3.6e-10 39.3 3.2 6.4e-10 38.5 0.8 2.2 2 0 0 2 2 2 1 WH2 motif Ribosomal_60s PF00428.19 OAP60623.1 - 0.046 14.3 19.4 0.88 10.2 6.7 2.3 1 1 1 2 2 2 0 60s Acidic ribosomal protein DUF3431 PF11913.8 OAP60624.1 - 5.3e-16 59.1 0.1 5.9e-15 55.6 0.1 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF3431) CHORD PF04968.12 OAP60625.1 - 8.9e-35 119.2 9.7 2.9e-25 88.7 5.7 2.4 2 0 0 2 2 2 2 CHORD CS PF04969.16 OAP60625.1 - 4.3e-14 53.3 0.0 1.1e-13 51.9 0.0 1.7 1 0 0 1 1 1 1 CS domain BTK PF00779.19 OAP60625.1 - 0.15 11.9 5.4 0.45 10.4 0.3 2.7 2 0 0 2 2 2 0 BTK motif SIR2 PF02146.17 OAP60628.1 - 1.2e-28 100.3 0.0 7.4e-28 97.7 0.0 2.1 1 1 0 1 1 1 1 Sir2 family Med16 PF11635.8 OAP60629.1 - 5.1e-52 176.8 0.0 9.1e-52 176.0 0.0 1.4 1 1 0 1 1 1 1 Mediator complex subunit 16 ANAPC4_WD40 PF12894.7 OAP60629.1 - 0.11 12.8 0.0 0.43 10.9 0.0 2.1 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain Ribosomal_L29 PF00831.23 OAP60630.1 - 6.6e-19 67.6 0.3 6.6e-19 67.6 0.3 1.9 2 1 0 2 2 2 1 Ribosomal L29 protein V-SNARE_C PF12352.8 OAP60631.1 - 1.2e-15 57.5 0.6 1.2e-15 57.5 0.6 2.7 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus GOLGA2L5 PF15070.6 OAP60631.1 - 0.0011 17.7 6.2 0.0015 17.3 6.2 1.3 1 0 0 1 1 1 1 Putative golgin subfamily A member 2-like protein 5 Syntaxin-6_N PF09177.11 OAP60631.1 - 0.053 14.1 5.6 0.056 14.0 2.6 2.4 1 1 1 2 2 2 0 Syntaxin 6, N-terminal FlgT_M PF16539.5 OAP60631.1 - 0.14 12.3 2.1 0.18 11.9 1.9 1.4 1 1 0 1 1 1 0 Flagellar assembly protein T, middle domain Surfac_D-trimer PF09006.11 OAP60631.1 - 0.17 11.8 0.2 0.57 10.1 0.0 2.0 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation FliD_N PF02465.18 OAP60631.1 - 0.38 11.5 2.1 3 8.6 0.0 2.6 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus CHAD PF05235.14 OAP60631.1 - 0.51 10.3 7.6 0.083 12.8 2.3 2.1 1 1 1 2 2 2 0 CHAD domain Atg14 PF10186.9 OAP60631.1 - 0.97 8.5 9.5 3.1 6.8 9.6 1.6 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Sec34 PF04136.15 OAP60631.1 - 1.3 8.9 6.8 2.5 8.0 2.2 2.8 2 1 2 4 4 4 0 Sec34-like family Spc7 PF08317.11 OAP60631.1 - 2.5 6.9 8.9 1.2 7.9 6.8 1.5 2 0 0 2 2 2 0 Spc7 kinetochore protein ATP-synt_10 PF05176.14 OAP60632.1 - 7.5e-67 225.3 0.0 9.9e-67 224.9 0.0 1.1 1 0 0 1 1 1 1 ATP10 protein DNA_pol_B_palm PF14792.6 OAP60633.1 - 2.3e-29 101.9 0.0 6.8e-29 100.4 0.0 1.9 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_lambd_f PF10391.9 OAP60633.1 - 1.8e-20 72.5 0.4 3.8e-20 71.5 0.4 1.6 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.6 OAP60633.1 - 2.1e-11 44.0 0.2 4.3e-11 43.0 0.2 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain Zn_clus PF00172.18 OAP60633.1 - 0.0017 18.4 4.6 0.0041 17.2 4.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BRCT_2 PF16589.5 OAP60633.1 - 0.002 18.5 0.0 0.0042 17.5 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 OAP60633.1 - 0.0033 17.8 0.0 0.0067 16.8 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain NTP_transf_2 PF01909.23 OAP60633.1 - 0.0059 16.9 0.0 0.013 15.8 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain zf-BED PF02892.15 OAP60633.1 - 0.051 13.6 2.0 0.064 13.3 0.2 2.1 2 0 0 2 2 2 0 BED zinc finger 5_3_exonuc PF01367.20 OAP60633.1 - 0.11 13.1 0.0 0.35 11.5 0.0 1.8 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold CRC_subunit PF08624.10 OAP60634.1 - 1.2e-51 174.6 0.2 1.8e-51 174.1 0.2 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit AT_hook PF02178.19 OAP60634.1 - 1.8 8.7 6.4 6.5 7.0 6.4 2.1 1 0 0 1 1 1 0 AT hook motif FAD_binding_3 PF01494.19 OAP60635.1 - 1e-22 80.9 0.4 3.2e-22 79.3 0.4 1.7 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 OAP60635.1 - 2.8e-09 36.6 2.4 1.9e-05 24.0 0.8 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAP60635.1 - 1.2e-07 31.7 4.3 0.002 17.8 3.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.17 OAP60635.1 - 2.9e-06 26.7 1.6 0.0018 17.5 1.6 2.2 1 1 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 OAP60635.1 - 4.6e-06 25.6 2.1 0.0028 16.4 1.3 2.2 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox PF00070.27 OAP60635.1 - 5.2e-06 26.9 0.7 0.0004 20.9 0.3 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAP60635.1 - 5.3e-06 26.6 0.6 1.3e-05 25.4 0.6 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 OAP60635.1 - 2.1e-05 23.8 5.6 3.5e-05 23.1 2.7 2.2 1 1 1 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 OAP60635.1 - 3.8e-05 22.9 1.5 0.00037 19.6 1.5 2.1 1 1 0 1 1 1 1 Lycopene cyclase protein GIDA PF01134.22 OAP60635.1 - 5.2e-05 22.5 1.1 7.1e-05 22.0 1.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Trp_halogenase PF04820.14 OAP60635.1 - 0.0013 17.6 3.2 0.0065 15.4 1.0 2.5 2 1 1 3 3 3 1 Tryptophan halogenase Amino_oxidase PF01593.24 OAP60635.1 - 0.0021 17.4 0.2 1.6 8.0 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 OAP60635.1 - 0.0048 16.3 2.6 0.0087 15.4 2.6 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 OAP60635.1 - 0.024 13.9 0.4 0.024 13.9 0.4 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 OAP60635.1 - 0.2 10.9 4.8 0.59 9.3 4.5 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase MCRA PF06100.11 OAP60635.1 - 0.24 10.2 0.9 2.5 6.8 0.6 2.4 3 0 0 3 3 3 0 MCRA family NAD_binding_9 PF13454.6 OAP60635.1 - 0.42 10.6 1.6 2.5 8.0 0.4 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding MFS_1 PF07690.16 OAP60636.1 - 6.4e-30 104.3 26.0 6.4e-30 104.3 26.0 1.8 1 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 OAP60636.1 - 6.6e-05 21.5 1.1 0.00011 20.8 1.1 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) FAM70 PF14967.6 OAP60636.1 - 0.032 13.7 2.4 0.036 13.5 1.3 1.5 2 0 0 2 2 2 0 FAM70 protein Fungal_trans PF04082.18 OAP60637.1 - 1.2e-07 31.1 0.8 4.6e-06 25.9 0.8 2.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain SLD3 PF08639.10 OAP60638.1 - 7.3e-129 431.0 17.5 7.3e-129 431.0 17.5 1.6 2 0 0 2 2 2 1 DNA replication regulator SLD3 GTP1_OBG PF01018.22 OAP60638.1 - 0.14 11.7 0.0 0.51 9.9 0.0 1.8 2 0 0 2 2 2 0 GTP1/OBG Syntaxin_2 PF14523.6 OAP60639.1 - 6.2e-21 74.7 5.3 5.6e-20 71.6 1.2 2.4 2 0 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.19 OAP60639.1 - 2.6e-16 59.4 1.3 6.1e-16 58.2 1.3 1.7 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 OAP60639.1 - 0.00081 19.1 10.1 0.012 15.3 10.0 2.4 1 1 0 1 1 1 1 Syntaxin Prominin PF05478.11 OAP60639.1 - 0.006 14.6 1.1 0.0083 14.1 0.2 1.6 2 0 0 2 2 2 1 Prominin Nitr_red_assoc PF09655.10 OAP60639.1 - 0.013 16.2 0.1 0.023 15.3 0.1 1.4 1 0 0 1 1 1 0 Conserved nitrate reductase-associated protein (Nitr_red_assoc) DUF883 PF05957.13 OAP60639.1 - 0.085 13.5 3.8 0.32 11.6 0.2 2.7 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) PMC2NT PF08066.12 OAP60639.1 - 0.2 12.4 1.3 0.38 11.5 0.1 2.0 2 0 0 2 2 2 0 PMC2NT (NUC016) domain DUF3829 PF12889.7 OAP60639.1 - 0.58 9.6 2.1 4.4 6.7 0.2 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3829) Ndc1_Nup PF09531.10 OAP60640.1 - 9.5e-148 493.6 0.8 1.2e-147 493.3 0.8 1.1 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup IKI3 PF04762.12 OAP60641.1 - 7.4e-276 917.8 0.0 8.9e-276 917.5 0.0 1.1 1 0 0 1 1 1 1 IKI3 family ANAPC4_WD40 PF12894.7 OAP60641.1 - 9.4e-05 22.6 0.3 5 7.5 0.1 4.4 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain LysR_substrate PF03466.20 OAP60641.1 - 0.02 14.2 0.1 0.11 11.9 0.0 2.1 2 0 0 2 2 2 0 LysR substrate binding domain SNAP PF14938.6 OAP60641.1 - 0.45 9.9 5.7 0.74 9.2 5.7 1.2 1 0 0 1 1 1 0 Soluble NSF attachment protein, SNAP TPR_7 PF13176.6 OAP60641.1 - 4.5 7.5 8.3 1.2 9.3 0.4 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat COX7C PF02935.16 OAP60642.1 - 4.9e-24 84.4 3.7 5.4e-24 84.2 3.7 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc rRNA_proc-arch PF13234.6 OAP60643.1 - 2.3e-88 296.6 0.7 5e-88 295.5 0.7 1.6 1 0 0 1 1 1 1 rRNA-processing arch domain Cut8 PF08559.10 OAP60643.1 - 4.6e-59 199.9 0.0 9.4e-59 198.9 0.0 1.5 1 0 0 1 1 1 1 Cut8, nuclear proteasome tether protein DSHCT PF08148.12 OAP60643.1 - 1.3e-52 177.8 1.2 4.2e-52 176.1 1.2 1.9 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.29 OAP60643.1 - 2.7e-18 66.3 0.0 7.9e-18 64.8 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAP60643.1 - 2.1e-06 28.0 0.0 1.2e-05 25.6 0.0 2.2 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAP60643.1 - 1.1e-05 25.5 0.0 4.1e-05 23.6 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit T2SSE PF00437.20 OAP60643.1 - 0.033 13.2 0.0 0.092 11.8 0.0 1.7 1 0 0 1 1 1 0 Type II/IV secretion system protein ATPase_2 PF01637.18 OAP60643.1 - 0.065 13.1 0.0 0.23 11.3 0.0 1.9 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Cyto_heme_lyase PF01265.17 OAP60644.1 - 4.6e-32 111.8 14.1 6.1e-29 101.5 14.1 3.1 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase MDD_C PF18376.1 OAP60645.1 - 3.5e-64 216.0 0.0 5.7e-64 215.3 0.0 1.3 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 OAP60645.1 - 5.4e-09 36.2 0.8 1.2e-08 35.1 0.8 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain FANCI_S3 PF14677.6 OAP60645.1 - 0.073 12.8 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 FANCI solenoid 3 FMO-like PF00743.19 OAP60646.1 - 2.7e-14 52.5 0.1 1.9e-13 49.7 0.1 2.0 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OAP60646.1 - 1e-13 51.2 0.1 3.2e-13 49.6 0.1 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAP60646.1 - 6.4e-09 35.5 0.0 1.2e-07 31.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAP60646.1 - 2.4e-08 33.5 0.0 6.1e-07 28.9 0.0 2.4 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 OAP60646.1 - 3e-08 33.8 0.0 9.9e-07 28.9 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 OAP60646.1 - 1.9e-06 27.3 0.0 3.1e-05 23.3 0.0 2.2 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 OAP60646.1 - 2.1e-05 24.3 1.4 0.00076 19.2 0.2 3.0 3 1 1 4 4 4 1 FAD dependent oxidoreductase Mqo PF06039.15 OAP60646.1 - 2.5e-05 23.0 0.5 0.0064 15.1 0.1 2.8 3 1 1 4 4 4 2 Malate:quinone oxidoreductase (Mqo) Pyr_redox PF00070.27 OAP60646.1 - 0.0011 19.4 0.0 0.24 12.0 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 OAP60646.1 - 0.015 15.4 0.1 0.27 11.3 0.0 2.8 4 0 0 4 4 4 0 Shikimate / quinate 5-dehydrogenase Lycopene_cycl PF05834.12 OAP60646.1 - 0.04 12.9 0.0 0.74 8.8 0.0 2.8 4 0 0 4 4 4 0 Lycopene cyclase protein FAD_binding_2 PF00890.24 OAP60646.1 - 0.054 12.6 0.4 0.11 11.5 0.0 1.7 2 0 0 2 2 2 0 FAD binding domain NAD_binding_9 PF13454.6 OAP60646.1 - 0.061 13.3 0.6 40 4.2 0.1 3.3 3 0 0 3 3 3 0 FAD-NAD(P)-binding NAD_binding_7 PF13241.6 OAP60646.1 - 0.11 12.9 0.0 0.28 11.6 0.0 1.8 2 0 0 2 2 2 0 Putative NAD(P)-binding zf-met2 PF12907.7 OAP60647.1 - 9.8e-12 44.8 3.2 1.5e-11 44.2 3.2 1.3 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.14 OAP60647.1 - 6.1e-07 30.2 9.4 6.1e-07 30.2 9.4 1.7 2 0 0 2 2 2 1 4F5 protein family zf-C2H2_4 PF13894.6 OAP60647.1 - 0.033 15.0 0.1 0.059 14.2 0.1 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger Aminotran_3 PF00202.21 OAP60648.1 - 1e-81 274.7 0.0 1.4e-81 274.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 OAP60648.1 - 0.016 14.4 0.0 0.035 13.3 0.0 1.5 1 0 0 1 1 1 0 Aminotransferase class I and II AAA PF00004.29 OAP60651.1 - 5.5e-85 282.5 0.0 1.8e-41 141.7 0.0 2.8 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OAP60651.1 - 2.8e-24 84.6 0.2 8.5e-13 47.9 0.0 3.1 2 0 0 2 2 2 2 AAA+ lid domain RuvB_N PF05496.12 OAP60651.1 - 6.4e-13 48.8 0.0 1.2e-07 31.7 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 OAP60651.1 - 1.7e-10 41.6 5.4 0.00024 21.6 0.9 4.9 3 2 1 4 4 3 2 AAA ATPase domain AAA_22 PF13401.6 OAP60651.1 - 2.2e-10 41.0 1.9 0.0077 16.5 0.0 4.5 3 2 1 4 4 3 2 AAA domain AAA_2 PF07724.14 OAP60651.1 - 4.4e-10 40.0 0.0 0.00016 21.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 OAP60651.1 - 1.6e-09 37.9 0.3 0.00064 19.7 0.1 3.8 4 1 0 4 4 3 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 OAP60651.1 - 9.4e-09 35.6 0.1 0.00032 20.9 0.0 3.2 4 0 0 4 4 2 2 AAA domain AAA_14 PF13173.6 OAP60651.1 - 1.4e-08 34.8 0.0 0.00021 21.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 OAP60651.1 - 4.6e-08 33.5 0.0 0.00011 22.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 OAP60651.1 - 5.8e-08 33.1 0.0 0.0013 19.1 0.0 3.1 2 1 0 2 2 2 2 RNA helicase AAA_25 PF13481.6 OAP60651.1 - 1.2e-07 31.5 1.5 0.38 10.3 0.0 3.7 2 1 1 3 3 3 3 AAA domain AAA_18 PF13238.6 OAP60651.1 - 1.8e-07 31.8 0.0 0.00035 21.1 0.0 3.0 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 OAP60651.1 - 3.7e-07 29.7 0.7 0.005 16.3 0.0 2.9 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 OAP60651.1 - 7.1e-07 29.1 0.0 0.0068 16.2 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein TIP49 PF06068.13 OAP60651.1 - 9.5e-07 28.3 0.0 0.00024 20.4 0.0 2.4 2 0 0 2 2 2 1 TIP49 P-loop domain ABC_tran PF00005.27 OAP60651.1 - 5.1e-06 27.0 0.8 0.49 10.9 0.0 4.2 4 0 0 4 4 4 2 ABC transporter TniB PF05621.11 OAP60651.1 - 6e-06 25.8 0.2 1.7 8.0 0.0 4.4 3 1 0 4 4 4 1 Bacterial TniB protein Zeta_toxin PF06414.12 OAP60651.1 - 8.1e-06 25.3 0.9 0.016 14.5 0.0 3.6 4 0 0 4 4 4 1 Zeta toxin Rad17 PF03215.15 OAP60651.1 - 9.4e-06 25.7 0.0 0.0075 16.2 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_3 PF07726.11 OAP60651.1 - 1.1e-05 25.3 0.0 0.0066 16.3 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Cytidylate_kin2 PF13189.6 OAP60651.1 - 1.4e-05 25.4 0.0 0.00068 19.8 0.0 2.5 2 0 0 2 2 2 1 Cytidylate kinase-like family TsaE PF02367.17 OAP60651.1 - 3.3e-05 23.9 0.0 0.081 12.9 0.0 2.3 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase PF06745.13 OAP60651.1 - 7e-05 22.3 0.2 0.26 10.6 0.0 3.4 2 1 1 3 3 3 1 KaiC AAA_11 PF13086.6 OAP60651.1 - 9.5e-05 22.3 0.7 0.3 10.8 0.0 2.9 3 0 0 3 3 3 2 AAA domain NACHT PF05729.12 OAP60651.1 - 0.00019 21.4 4.9 0.095 12.6 0.0 4.6 5 2 1 6 6 6 1 NACHT domain Vps4_C PF09336.10 OAP60651.1 - 0.00021 21.2 0.1 0.12 12.3 0.0 3.2 3 0 0 3 3 3 1 Vps4 C terminal oligomerisation domain Viral_helicase1 PF01443.18 OAP60651.1 - 0.00026 20.8 0.0 0.4 10.4 0.0 2.3 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_17 PF13207.6 OAP60651.1 - 0.00034 21.0 1.6 0.043 14.2 0.1 3.1 3 1 0 3 3 2 1 AAA domain Parvo_NS1 PF01057.17 OAP60651.1 - 0.0005 19.3 0.1 0.29 10.2 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_7 PF12775.7 OAP60651.1 - 0.00065 19.3 0.0 0.29 10.6 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_24 PF13479.6 OAP60651.1 - 0.00081 19.2 0.0 0.99 9.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 OAP60651.1 - 0.00083 19.1 0.0 1.9 8.1 0.0 3.0 2 1 0 2 2 2 2 Sigma-54 interaction domain SKI PF01202.22 OAP60651.1 - 0.001 19.2 1.9 0.29 11.3 0.0 3.3 3 0 0 3 3 3 1 Shikimate kinase PhoH PF02562.16 OAP60651.1 - 0.0021 17.5 0.1 2.2 7.7 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein Sigma54_activ_2 PF14532.6 OAP60651.1 - 0.003 17.7 0.0 0.19 11.9 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain ATPase_2 PF01637.18 OAP60651.1 - 0.0045 16.9 0.1 9 6.1 0.0 3.4 3 1 1 4 4 4 0 ATPase domain predominantly from Archaea NB-ARC PF00931.22 OAP60651.1 - 0.0046 16.2 0.9 2.2 7.4 0.0 3.2 3 0 0 3 3 3 1 NB-ARC domain AAA_19 PF13245.6 OAP60651.1 - 0.005 17.2 0.1 0.67 10.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 OAP60651.1 - 0.0054 15.9 0.0 0.31 10.2 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AFG1_ATPase PF03969.16 OAP60651.1 - 0.021 13.8 0.0 0.33 9.8 0.0 2.6 2 0 0 2 2 2 0 AFG1-like ATPase Guanylate_kin PF00625.21 OAP60651.1 - 0.024 14.3 1.3 2.9 7.5 0.0 3.8 3 2 2 5 5 4 0 Guanylate kinase AAA_30 PF13604.6 OAP60651.1 - 0.027 14.2 0.0 8.7 6.0 0.0 2.8 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 OAP60651.1 - 0.027 13.7 0.1 0.88 8.7 0.1 2.5 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Cytidylate_kin PF02224.18 OAP60651.1 - 0.043 13.5 0.2 0.49 10.1 0.0 2.4 2 0 0 2 2 2 0 Cytidylate kinase DAP3 PF10236.9 OAP60651.1 - 0.052 12.7 0.0 22 4.1 0.0 3.2 2 1 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 ResIII PF04851.15 OAP60651.1 - 0.053 13.5 0.1 4.3 7.3 0.0 2.7 3 1 0 3 3 2 0 Type III restriction enzyme, res subunit Bac_DnaA PF00308.18 OAP60651.1 - 0.054 13.3 0.0 14 5.5 0.0 3.0 3 1 0 3 3 3 0 Bacterial dnaA protein AAA_23 PF13476.6 OAP60651.1 - 0.065 13.7 3.1 2.8 8.4 0.0 3.2 3 0 0 3 3 3 0 AAA domain Hydin_ADK PF17213.3 OAP60651.1 - 0.068 13.4 2.5 0.3 11.3 0.0 2.8 3 0 0 3 3 3 0 Hydin Adenylate kinase-like domain DUF4260 PF14079.6 OAP60652.1 - 5.2e-41 139.1 0.4 5.9e-41 139.0 0.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4260) Ank_5 PF13857.6 OAP60653.1 - 5.1e-19 68.1 0.0 2.8e-13 49.8 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeats (many copies) VPS9 PF02204.18 OAP60653.1 - 8.1e-16 58.1 0.0 3.3e-15 56.2 0.0 2.0 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ank_2 PF12796.7 OAP60653.1 - 2.3e-13 50.5 0.0 0.00049 20.6 0.0 4.0 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OAP60653.1 - 2.1e-08 33.7 0.3 0.053 14.1 0.0 5.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 OAP60653.1 - 1.2e-06 29.0 0.0 0.059 14.0 0.0 4.8 5 0 0 5 5 5 2 Ankyrin repeats (many copies) Ank PF00023.30 OAP60653.1 - 3.8e-06 27.1 0.0 0.027 14.9 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat PX PF00787.24 OAP60653.1 - 0.00012 22.0 0.3 0.00012 22.0 0.3 2.1 2 0 0 2 2 2 1 PX domain DUF447 PF04289.12 OAP60653.1 - 0.12 12.1 0.0 0.3 10.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF447) Inhibitor_I78 PF11720.8 OAP60654.1 - 3.7e-10 39.7 0.0 4.8e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase inhibitor I78 family potato_inhibit PF00280.18 OAP60654.1 - 0.00016 22.3 0.1 0.00022 21.8 0.1 1.2 1 0 0 1 1 1 1 Potato inhibitor I family Tim44 PF04280.15 OAP60655.1 - 7.2e-35 120.2 0.0 1.3e-34 119.4 0.0 1.4 1 0 0 1 1 1 1 Tim44-like domain TRAP_alpha PF03896.16 OAP60655.1 - 7.7 5.6 8.4 2.7 7.1 2.1 2.2 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Ribosomal_S11 PF00411.19 OAP60656.1 - 8.5e-06 26.1 0.5 0.041 14.3 0.0 2.7 2 1 1 3 3 3 2 Ribosomal protein S11 Sporozoite_P67 PF05642.11 OAP60656.1 - 0.08 11.0 0.4 0.12 10.4 0.2 1.4 2 0 0 2 2 2 0 Sporozoite P67 surface antigen RIC1 PF07064.13 OAP60657.1 - 2.4e-80 269.6 0.0 3.9e-80 268.9 0.0 1.3 1 0 0 1 1 1 1 RIC1 ANAPC4_WD40 PF12894.7 OAP60657.1 - 2.7e-06 27.6 0.0 0.13 12.6 0.0 3.5 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OAP60657.1 - 0.02 15.8 1.1 3.2 8.8 0.2 3.9 3 1 0 3 3 3 0 WD domain, G-beta repeat Abhydrolase_3 PF07859.13 OAP60659.1 - 3e-49 167.7 0.0 4.2e-49 167.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 OAP60659.1 - 6.9e-07 28.5 0.0 2.2e-06 26.8 0.0 1.7 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 OAP60659.1 - 0.00016 21.3 0.0 0.0012 18.4 0.0 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 OAP60659.1 - 0.0028 18.3 1.0 0.0078 16.8 1.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAP60659.1 - 0.0039 16.9 0.0 0.006 16.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold AXE1 PF05448.12 OAP60659.1 - 0.069 11.8 0.0 0.17 10.5 0.0 1.6 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Sugar_tr PF00083.24 OAP60660.1 - 1.5e-66 225.1 22.4 1.8e-66 224.9 22.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP60660.1 - 2.4e-16 59.6 25.2 5.2e-16 58.5 19.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily AcetylCoA_hydro PF02550.15 OAP60662.1 - 2.5e-51 174.5 0.0 4e-51 173.8 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.6 OAP60662.1 - 7.2e-42 142.9 0.0 1.2e-41 142.2 0.0 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain SBP56 PF05694.11 OAP60663.1 - 4.7e-185 615.7 0.0 5.7e-185 615.5 0.0 1.1 1 0 0 1 1 1 1 56kDa selenium binding protein (SBP56) Sugar_tr PF00083.24 OAP60663.1 - 4.4e-84 282.9 19.4 5.7e-84 282.6 19.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP60663.1 - 4.9e-12 45.4 35.3 1.3e-09 37.4 9.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily LVIVD PF08309.11 OAP60663.1 - 0.014 14.7 0.0 0.035 13.4 0.0 1.6 1 0 0 1 1 1 0 LVIVD repeat SET PF00856.28 OAP60664.1 - 3.9e-08 33.8 0.7 1.2e-07 32.2 0.1 2.3 2 1 0 2 2 2 1 SET domain PHD PF00628.29 OAP60664.1 - 0.00018 21.3 10.7 0.00035 20.4 10.7 1.5 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.6 OAP60664.1 - 0.69 9.9 7.9 1.6 8.7 7.9 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 FGGY_C PF02782.16 OAP60665.1 - 1.2e-48 165.5 0.1 1.8e-48 164.9 0.1 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 OAP60665.1 - 1.1e-20 74.3 0.1 2.4e-19 69.9 0.1 2.6 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.20 OAP60665.1 - 0.076 12.5 0.0 0.24 10.8 0.0 1.8 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family zf-RING_2 PF13639.6 OAP60666.1 - 1.2e-10 41.5 3.3 2e-10 40.8 3.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 OAP60666.1 - 7e-08 32.1 0.3 7e-08 32.1 0.3 1.7 2 0 0 2 2 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 OAP60666.1 - 7.8e-08 32.0 2.5 1.3e-07 31.3 2.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAP60666.1 - 6e-07 29.2 2.1 9.7e-07 28.6 2.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OAP60666.1 - 1.1e-06 28.8 4.8 2.3e-06 27.8 4.8 1.5 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 OAP60666.1 - 1.6e-05 24.8 1.0 2.4e-05 24.3 0.4 1.6 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 OAP60666.1 - 9.1e-05 22.3 1.6 0.00015 21.6 1.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 OAP60666.1 - 0.0015 18.1 4.1 0.0025 17.4 4.1 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type PIG-L PF02585.17 OAP60666.1 - 0.0034 18.0 0.1 0.011 16.3 0.0 1.8 2 0 0 2 2 2 1 GlcNAc-PI de-N-acetylase zf-ANAPC11 PF12861.7 OAP60666.1 - 0.0088 16.1 0.6 0.017 15.2 0.6 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 OAP60666.1 - 0.021 15.0 1.5 0.041 14.0 1.5 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 OAP60666.1 - 0.039 13.8 1.9 0.08 12.8 1.9 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OAP60666.1 - 0.05 13.5 1.5 0.092 12.6 1.5 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 PHD PF00628.29 OAP60666.1 - 0.099 12.5 2.7 0.18 11.7 2.7 1.4 1 0 0 1 1 1 0 PHD-finger zf-RING_4 PF14570.6 OAP60666.1 - 0.13 12.1 1.3 0.31 10.9 1.3 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RINGv PF12906.7 OAP60666.1 - 0.16 12.1 4.0 0.33 11.1 4.0 1.5 1 0 0 1 1 1 0 RING-variant domain zf-C3H2C3 PF17122.5 OAP60666.1 - 6.3 6.9 6.8 19 5.4 6.8 1.8 1 1 0 1 1 1 0 Zinc-finger HSP20 PF00011.21 OAP60668.1 - 8e-09 35.6 0.0 1.1e-06 28.7 0.0 2.1 2 0 0 2 2 2 2 Hsp20/alpha crystallin family PIH1_CS PF18201.1 OAP60668.1 - 0.12 12.8 0.0 0.19 12.1 0.0 1.6 1 1 0 1 1 1 0 PIH1 CS-like domain Abhydrolase_9 PF10081.9 OAP60669.1 - 0.031 13.3 5.8 0.043 12.9 5.8 1.1 1 0 0 1 1 1 0 Alpha/beta-hydrolase family SelP_N PF04592.14 OAP60669.1 - 0.12 11.8 9.1 0.17 11.3 9.1 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Zip PF02535.22 OAP60669.1 - 0.65 9.2 3.3 0.74 9.0 3.3 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Nucleo_P87 PF07267.11 OAP60669.1 - 1.5 7.6 7.3 1.8 7.3 7.3 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Cyclase PF04199.13 OAP60671.1 - 1.1e-07 32.2 0.0 1.7e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 Putative cyclase RCC1 PF00415.18 OAP60672.1 - 1.9e-47 159.7 11.1 6.2e-09 36.4 0.0 7.5 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OAP60672.1 - 1.9e-33 113.5 29.1 6.9e-08 32.1 0.4 6.7 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat dCMP_cyt_deam_1 PF00383.23 OAP60673.1 - 9.2e-26 89.7 0.0 1.2e-25 89.3 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 OAP60673.1 - 1.6e-20 73.3 0.0 2e-20 72.9 0.0 1.1 1 0 0 1 1 1 1 MafB19-like deaminase SNAD4 PF18750.1 OAP60673.1 - 0.0014 18.7 0.0 0.0023 18.0 0.0 1.3 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 Bd3614-deam PF14439.6 OAP60673.1 - 0.0022 18.1 0.7 0.17 12.0 0.1 2.3 1 1 1 2 2 2 1 Bd3614-like deaminase APOBEC3 PF18771.1 OAP60673.1 - 0.0024 18.0 0.0 0.0036 17.4 0.0 1.2 1 0 0 1 1 1 1 APOBEC3 APOBEC4_like PF18774.1 OAP60673.1 - 0.003 17.5 0.0 0.0042 17.0 0.0 1.2 1 0 0 1 1 1 1 APOBEC4-like -AID/APOBEC-deaminase NAD2 PF18782.1 OAP60673.1 - 0.013 15.6 0.0 0.019 15.1 0.0 1.2 1 0 0 1 1 1 0 Novel AID APOBEC clade 2 NAD1 PF18778.1 OAP60673.1 - 0.04 14.0 0.0 0.064 13.3 0.0 1.3 1 0 0 1 1 1 0 Novel AID APOBEC clade 1 APOBEC2 PF18772.1 OAP60673.1 - 0.042 13.9 0.0 0.061 13.4 0.0 1.2 1 0 0 1 1 1 0 APOBEC2 APOBEC_N PF08210.11 OAP60673.1 - 0.073 13.0 0.0 0.094 12.6 0.0 1.2 1 0 0 1 1 1 0 APOBEC-like N-terminal domain Cytochrom_B558a PF05038.13 OAP60674.1 - 0.36 10.4 2.7 0.78 9.3 2.7 1.5 1 0 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit CAP_N PF01213.19 OAP60674.1 - 0.52 9.7 3.5 0.78 9.2 3.5 1.5 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal F-box-like PF12937.7 OAP60675.1 - 0.00079 19.3 0.2 0.0082 16.0 0.0 2.4 2 0 0 2 2 2 1 F-box-like ADH_N PF08240.12 OAP60676.1 - 1e-24 86.5 0.8 2.2e-24 85.4 0.4 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAP60676.1 - 5.3e-19 68.5 0.1 9.6e-19 67.7 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAP60676.1 - 4.8e-09 37.4 0.1 9.8e-09 36.4 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase BKACE PF05853.12 OAP60676.1 - 0.0013 18.1 0.0 0.0021 17.4 0.0 1.3 1 0 0 1 1 1 1 beta-keto acid cleavage enzyme AlaDh_PNT_C PF01262.21 OAP60676.1 - 0.0016 17.8 0.2 0.0024 17.2 0.2 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain YAcAr PF10686.9 OAP60676.1 - 0.03 14.3 0.2 0.095 12.7 0.0 1.9 3 0 0 3 3 3 0 YspA, cpYpsA-related SLOG family adh_short PF00106.25 OAP60676.1 - 0.13 11.7 0.2 0.13 11.7 0.2 1.7 2 0 0 2 2 2 0 short chain dehydrogenase Epimerase PF01370.21 OAP60676.1 - 0.14 11.6 0.1 0.21 11.0 0.1 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DapB_N PF01113.20 OAP60676.1 - 0.15 12.2 0.5 0.5 10.5 0.5 1.9 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus AhpC-TSA_2 PF13911.6 OAP60676.1 - 0.18 12.0 0.0 5 7.3 0.0 2.3 2 0 0 2 2 2 0 AhpC/TSA antioxidant enzyme 2-Hacid_dh_C PF02826.19 OAP60676.1 - 0.18 11.2 0.1 0.32 10.3 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Aldedh PF00171.22 OAP60677.1 - 1.3e-158 528.3 0.0 1.5e-158 528.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 OAP60677.1 - 0.00025 20.5 0.0 0.014 14.8 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1487) Ead_Ea22 PF13935.6 OAP60677.1 - 0.16 12.7 0.3 0.3 11.7 0.3 1.4 1 0 0 1 1 1 0 Ead/Ea22-like protein LuxC PF05893.14 OAP60677.1 - 0.16 10.9 0.2 0.26 10.3 0.2 1.2 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) Tetraspanin PF00335.20 OAP60678.1 - 0.0024 17.6 0.0 0.013 15.2 0.0 2.0 2 0 0 2 2 2 1 Tetraspanin family 7tm_3 PF00003.22 OAP60678.1 - 0.0039 17.0 0.2 0.0059 16.4 0.2 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR DUF1345 PF07077.11 OAP60678.1 - 0.018 14.8 1.2 0.96 9.1 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1345) Mem_trans PF03547.18 OAP60678.1 - 0.023 13.1 3.1 0.06 11.7 0.0 2.0 1 1 1 2 2 2 0 Membrane transport protein Orai-1 PF07856.12 OAP60678.1 - 0.063 13.0 0.6 0.083 12.6 0.1 1.4 2 0 0 2 2 2 0 Mediator of CRAC channel activity CRPA PF05745.11 OAP60678.1 - 0.076 13.0 0.7 0.14 12.1 0.7 1.4 1 0 0 1 1 1 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) Phage_holin_2_4 PF16082.5 OAP60678.1 - 0.29 10.9 0.0 0.29 10.9 0.0 2.4 3 0 0 3 3 3 0 Bacteriophage holin family, superfamily II-like Wzy_C PF04932.15 OAP60678.1 - 0.44 10.2 7.0 2 8.0 7.0 2.1 1 1 0 1 1 1 0 O-Antigen ligase SpoIIM PF01944.17 OAP60678.1 - 0.64 10.1 6.8 0.88 9.6 1.1 2.8 3 0 0 3 3 3 0 Stage II sporulation protein M Y_phosphatase PF00102.27 OAP60679.1 - 6.2e-61 205.9 0.0 2.1e-59 201.0 0.0 2.5 1 1 0 1 1 1 1 Protein-tyrosine phosphatase Rhodanese PF00581.20 OAP60679.1 - 3.9e-07 30.5 0.0 9.4e-07 29.3 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain DSPc PF00782.20 OAP60679.1 - 0.0052 16.6 0.1 0.01 15.6 0.1 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 OAP60679.1 - 0.03 14.3 0.2 0.063 13.2 0.2 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family COX16 PF14138.6 OAP60680.1 - 6.6e-30 103.5 0.1 8.9e-30 103.0 0.1 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 AIMP2_LysRS_bd PF16780.5 OAP60680.1 - 0.073 12.8 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 AIMP2 lysyl-tRNA synthetase binding domain HET PF06985.11 OAP60681.1 - 1.1e-10 42.1 0.0 3.9e-07 30.5 0.0 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) HLH PF00010.26 OAP60682.1 - 1.4e-08 34.6 0.0 3.7e-08 33.2 0.0 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Mucin15 PF15672.5 OAP60683.1 - 0.012 15.1 1.8 0.016 14.7 1.8 1.1 1 0 0 1 1 1 0 Cell-membrane associated Mucin15 MARVEL PF01284.23 OAP60684.1 - 0.00047 20.2 16.0 0.0007 19.6 15.6 1.5 1 1 0 1 1 1 1 Membrane-associating domain Herpes_UL79 PF03049.14 OAP60684.1 - 0.03 14.0 0.6 0.048 13.3 0.6 1.3 1 0 0 1 1 1 0 UL79 family DUF202 PF02656.15 OAP60684.1 - 1.2 9.6 5.7 7.3 7.1 0.6 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF202) Zn_clus PF00172.18 OAP60685.1 - 3e-08 33.6 11.5 5.4e-08 32.8 11.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Nic96 PF04097.14 OAP60686.1 - 7e-195 649.1 0.0 8.7e-195 648.8 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 OPT PF03169.15 OAP60687.1 - 1.9e-204 680.8 37.4 2.3e-204 680.6 37.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Fe-ADH PF00465.19 OAP60689.1 - 7.8e-65 219.1 0.0 1e-64 218.7 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 OAP60689.1 - 2.1e-08 34.2 0.6 0.00056 19.7 0.1 2.1 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase AA_permease PF00324.21 OAP60691.1 - 8.2e-104 347.8 36.7 1e-103 347.5 36.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAP60691.1 - 2.3e-23 82.7 39.7 2.9e-23 82.4 39.7 1.1 1 0 0 1 1 1 1 Amino acid permease Dabb PF07876.12 OAP60692.1 - 7.8e-19 68.1 0.0 8.6e-19 68.0 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain DUF3638 PF12340.8 OAP60693.1 - 2.3e-86 288.8 0.3 7.3e-86 287.1 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 OAP60693.1 - 8.3e-11 41.1 0.0 1.6e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) Thioredoxin_13 PF18401.1 OAP60693.1 - 0.15 11.9 0.4 12 5.8 0.1 3.0 3 0 0 3 3 3 0 Thioredoxin-like domain HTH_32 PF13565.6 OAP60693.1 - 0.97 10.1 7.1 1 10.0 2.9 3.5 4 0 0 4 4 4 0 Homeodomain-like domain Lyase_aromatic PF00221.19 OAP60694.1 - 1.3e-140 469.1 1.3 1.6e-139 465.6 1.3 2.0 1 1 0 1 1 1 1 Aromatic amino acid lyase Beta-lactamase PF00144.24 OAP60695.1 - 2.6e-42 145.3 0.0 4e-42 144.6 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.20 OAP60695.1 - 0.0067 15.9 0.0 0.036 13.5 0.0 1.9 2 0 0 2 2 2 1 D-alanyl-D-alanine carboxypeptidase Beta-lactamase2 PF13354.6 OAP60695.1 - 0.013 15.1 0.0 0.025 14.2 0.0 1.4 1 0 0 1 1 1 0 Beta-lactamase enzyme family PAM2 PF07145.15 OAP60696.1 - 0.00052 19.5 15.2 1.2 9.0 0.0 5.0 4 0 0 4 4 4 3 Ataxin-2 C-terminal region Thioredoxin_6 PF13848.6 OAP60697.1 - 3.4e-18 66.2 0.0 6.6e-18 65.3 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain Fungal_trans_2 PF11951.8 OAP60697.1 - 1.5e-08 33.9 0.1 2.3e-08 33.3 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain 2OG-FeII_Oxy_3 PF13640.6 OAP60698.1 - 2.4e-09 38.0 0.0 6e-09 36.7 0.0 1.6 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily UQ_con PF00179.26 OAP60699.1 - 2.9e-35 121.0 0.0 4e-35 120.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OAP60699.1 - 0.1 12.3 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family B PIR PF00399.19 OAP60700.1 - 8.4e-05 22.0 0.7 0.00049 19.6 0.7 2.4 1 0 0 1 1 1 1 Yeast PIR protein repeat MMgT PF10270.9 OAP60701.1 - 2.3e-34 117.8 0.0 2.7e-34 117.5 0.0 1.1 1 0 0 1 1 1 1 Membrane magnesium transporter PEX11 PF05648.14 OAP60702.1 - 6e-23 81.5 0.5 1.1e-22 80.6 0.5 1.4 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) DUF4834 PF16118.5 OAP60702.1 - 5.2 8.1 7.2 0.6 11.1 2.4 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4834) DUF2981 PF11200.8 OAP60702.1 - 6.1 6.5 7.6 3 7.5 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2981) AIF_C PF14721.6 OAP60702.1 - 7.5 6.9 7.3 70 3.8 6.7 2.2 1 1 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Phosphoesterase PF04185.14 OAP60703.1 - 3.3e-61 207.4 6.5 6.1e-61 206.6 6.5 1.4 1 1 0 1 1 1 1 Phosphoesterase family VIT1 PF01988.19 OAP60704.1 - 8.4e-62 208.8 3.7 1.2e-61 208.4 3.7 1.2 1 0 0 1 1 1 1 VIT family MARVEL PF01284.23 OAP60704.1 - 0.03 14.4 1.8 0.05 13.6 1.8 1.4 1 0 0 1 1 1 0 Membrane-associating domain SLATT_fungal PF18142.1 OAP60704.1 - 0.24 11.4 1.0 0.61 10.1 1.0 1.7 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain Phosphoesterase PF04185.14 OAP60705.1 - 6.6e-37 127.5 2.9 2.2e-36 125.8 2.9 1.7 1 1 0 1 1 1 1 Phosphoesterase family HIF-1a_CTAD PF08778.10 OAP60705.1 - 0.15 11.7 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 HIF-1 alpha C terminal transactivation domain Cu-oxidase_3 PF07732.15 OAP60706.1 - 2.1e-44 150.3 1.8 1.4e-43 147.7 0.7 2.7 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.22 OAP60706.1 - 2.4e-41 141.5 0.9 3.7e-40 137.6 0.0 2.6 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 OAP60706.1 - 8.8e-38 129.1 7.6 3.3e-35 120.8 0.5 4.0 3 1 0 3 3 3 2 Multicopper oxidase HD-ZIP_N PF04618.12 OAP60706.1 - 0.051 14.1 0.1 0.12 12.9 0.1 1.6 1 0 0 1 1 1 0 HD-ZIP protein N terminus Glyco_hydro_17 PF00332.18 OAP60707.1 - 7.7e-23 81.6 0.9 3.2e-22 79.5 1.1 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 17 MHC_II_beta PF00969.19 OAP60707.1 - 0.056 13.5 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Class II histocompatibility antigen, beta domain DUF3405 PF11885.8 OAP60708.1 - 1.4e-229 763.0 1.1 1.7e-229 762.7 1.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) Cupin_2 PF07883.11 OAP60709.1 - 5.2e-07 29.3 0.0 8.1e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 OAP60709.1 - 0.054 13.2 0.0 0.14 11.9 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF861) MFS_1 PF07690.16 OAP60710.1 - 5.4e-37 127.5 29.6 8.2e-37 126.9 29.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily NCOA_u2 PF16665.5 OAP60711.1 - 0.064 13.6 0.2 1.8 8.9 0.2 2.3 1 1 0 1 1 1 0 Unstructured region on nuclear receptor coactivator protein HTH_Tnp_Mu_2 PF09039.11 OAP60711.1 - 0.1 12.7 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 Mu DNA binding, I gamma subdomain CoA_trans PF01144.23 OAP60712.1 - 2.4e-100 334.4 2.0 3.5e-59 199.8 0.2 2.1 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.6 OAP60712.1 - 0.0018 18.2 0.1 0.0039 17.1 0.1 1.5 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain Mito_carr PF00153.27 OAP60713.1 - 6.8e-48 160.6 0.5 2e-15 56.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Zn_clus PF00172.18 OAP60714.1 - 3.2e-07 30.4 7.8 6.1e-07 29.5 7.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAP60714.1 - 0.00052 19.1 0.4 0.0017 17.5 0.4 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain bZIP_1 PF00170.21 OAP60715.1 - 1.4e-07 31.5 15.0 4.3e-07 29.9 15.1 1.7 1 1 0 1 1 1 1 bZIP transcription factor ATG16 PF08614.11 OAP60715.1 - 1.6e-05 25.2 10.1 2.1e-05 24.9 10.1 1.1 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) TolA_bind_tri PF16331.5 OAP60715.1 - 0.00027 21.0 9.1 0.52 10.4 8.9 2.4 2 0 0 2 2 2 2 TolA binding protein trimerisation UPF0242 PF06785.11 OAP60715.1 - 0.00041 20.5 4.1 0.00048 20.3 4.1 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus DUF812 PF05667.11 OAP60715.1 - 0.0013 17.7 3.6 0.0016 17.5 3.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) TPR_MLP1_2 PF07926.12 OAP60715.1 - 0.0014 18.7 6.8 0.0025 17.9 6.8 1.4 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein DUF3450 PF11932.8 OAP60715.1 - 0.0019 17.5 7.4 0.0045 16.3 7.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) DUF3323 PF11796.8 OAP60715.1 - 0.0029 17.5 0.4 0.0039 17.1 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function N-terminus (DUF3323) bZIP_2 PF07716.15 OAP60715.1 - 0.0035 17.4 20.0 0.092 12.8 14.2 2.2 1 1 1 2 2 2 2 Basic region leucine zipper OEP PF02321.18 OAP60715.1 - 0.007 16.2 5.5 0.0099 15.7 5.5 1.3 1 0 0 1 1 1 1 Outer membrane efflux protein FPP PF05911.11 OAP60715.1 - 0.0079 14.5 4.2 0.0094 14.2 4.2 1.0 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil Jnk-SapK_ap_N PF09744.9 OAP60715.1 - 0.0082 16.4 8.3 0.015 15.5 8.2 1.4 2 0 0 2 2 1 1 JNK_SAPK-associated protein-1 COG7 PF10191.9 OAP60715.1 - 0.0098 14.2 6.1 0.016 13.5 6.1 1.3 1 0 0 1 1 1 1 Golgi complex component 7 (COG7) HAUS6_N PF14661.6 OAP60715.1 - 0.015 14.9 1.8 0.017 14.7 1.8 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF4618 PF15397.6 OAP60715.1 - 0.018 14.5 5.0 0.027 13.9 5.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) DUF16 PF01519.16 OAP60715.1 - 0.024 15.1 2.9 0.038 14.5 2.9 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF16 DUF724 PF05266.14 OAP60715.1 - 0.032 14.1 5.5 0.048 13.5 5.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Fib_alpha PF08702.10 OAP60715.1 - 0.044 14.0 10.2 0.089 13.0 8.6 1.9 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Macoilin PF09726.9 OAP60715.1 - 0.047 12.2 7.8 0.055 12.0 7.8 1.0 1 0 0 1 1 1 0 Macoilin family Exonuc_VII_L PF02601.15 OAP60715.1 - 0.065 12.8 5.9 0.081 12.5 5.9 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit ADIP PF11559.8 OAP60715.1 - 0.072 13.2 9.9 0.12 12.5 9.9 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding TSC22 PF01166.18 OAP60715.1 - 0.078 13.3 3.0 1.6 9.1 0.2 2.5 1 1 1 2 2 2 0 TSC-22/dip/bun family FapA PF03961.13 OAP60715.1 - 0.087 11.4 2.0 0.11 11.1 2.0 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A HIP1_clath_bdg PF16515.5 OAP60715.1 - 0.093 13.3 12.5 0.21 12.2 11.5 2.0 2 1 1 3 3 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF1664 PF07889.12 OAP60715.1 - 0.098 12.7 1.1 0.19 11.8 1.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Seryl_tRNA_N PF02403.22 OAP60715.1 - 0.099 12.9 3.4 0.18 12.1 3.4 1.3 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain U1snRNP70_N PF12220.8 OAP60715.1 - 0.12 13.1 5.5 0.26 11.9 5.5 1.6 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal TMF_DNA_bd PF12329.8 OAP60715.1 - 0.12 12.4 6.6 0.12 12.4 5.3 1.6 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF4407 PF14362.6 OAP60715.1 - 0.14 11.5 7.2 0.12 11.8 5.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) KxDL PF10241.9 OAP60715.1 - 0.15 12.4 8.1 0.18 12.1 7.0 1.6 2 0 0 2 2 1 0 Uncharacterized conserved protein bZIP_Maf PF03131.17 OAP60715.1 - 0.19 12.2 16.6 0.35 11.4 16.6 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor Sec34 PF04136.15 OAP60715.1 - 0.27 11.1 4.8 1.3 8.9 2.2 2.1 2 0 0 2 2 2 0 Sec34-like family TMPIT PF07851.13 OAP60715.1 - 0.33 10.2 4.2 0.46 9.7 4.2 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF1151 PF06625.11 OAP60715.1 - 0.48 10.4 11.6 0.72 9.8 11.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1151) SlyX PF04102.12 OAP60715.1 - 0.59 10.8 9.8 0.39 11.4 7.5 1.9 1 1 1 2 2 2 0 SlyX HemX PF04375.14 OAP60715.1 - 0.66 9.2 10.5 0.19 11.0 7.8 1.4 2 0 0 2 2 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF3682 PF12446.8 OAP60715.1 - 0.89 10.0 5.2 1.2 9.6 5.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) DivIC PF04977.15 OAP60715.1 - 1.2 9.0 13.4 0.14 11.9 3.4 2.3 1 1 1 2 2 2 0 Septum formation initiator DUF2040 PF09745.9 OAP60715.1 - 1.4 9.0 11.1 2.4 8.3 11.1 1.4 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 55 (DUF2040) ABC_tran_CTD PF16326.5 OAP60715.1 - 6.2 7.2 12.3 39 4.6 11.2 2.4 1 1 1 2 2 2 0 ABC transporter C-terminal domain ZapB PF06005.12 OAP60715.1 - 7.8 7.0 14.7 0.82 10.2 7.4 2.2 1 1 1 2 2 1 0 Cell division protein ZapB Csm1_N PF18504.1 OAP60715.1 - 8.5 6.8 11.5 0.29 11.5 1.3 2.4 1 1 2 3 3 3 0 Csm1 N-terminal domain Glycophorin_A PF01102.18 OAP60716.1 - 0.021 15.1 0.2 0.021 15.1 0.2 1.9 2 0 0 2 2 2 0 Glycophorin A DUF202 PF02656.15 OAP60716.1 - 0.28 11.6 2.6 6.3 7.3 0.0 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF202) Rcd1 PF04078.13 OAP60717.1 - 8.1e-119 395.7 0.0 1.5e-118 394.8 0.0 1.4 1 1 0 1 1 1 1 Cell differentiation family, Rcd1-like SbcCD_C PF13558.6 OAP60717.1 - 0.011 15.9 1.8 0.026 14.7 1.8 1.6 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Hid1 PF12722.7 OAP60717.1 - 0.9 7.6 4.8 1.1 7.3 4.8 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein baeRF_family10 PF18854.1 OAP60717.1 - 0.98 9.7 6.1 4.1 7.7 3.0 2.4 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 10 BAF1_ABF1 PF04684.13 OAP60717.1 - 4.5 6.2 12.6 6.1 5.8 12.6 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor PAT1 PF09770.9 OAP60717.1 - 6.3 4.9 15.1 7.3 4.7 15.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 NST1 PF13945.6 OAP60717.1 - 8.3 6.5 12.2 13 5.9 12.2 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator Aldo_ket_red PF00248.21 OAP60718.1 - 9.9e-64 215.3 0.0 1.1e-63 215.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF2256 PF10013.9 OAP60719.1 - 0.0059 16.7 1.7 0.019 15.1 1.7 1.9 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2256) TetR_C_11 PF16859.5 OAP60719.1 - 0.15 12.4 1.3 0.3 11.4 1.3 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Ecl1 PF12855.7 OAP60719.1 - 1.3 10.2 4.0 4.2 8.5 4.0 2.0 1 1 0 1 1 1 0 ECL1/2/3 zinc binding proteins Fungal_trans_2 PF11951.8 OAP60720.1 - 4e-07 29.2 0.9 4e-07 29.2 0.9 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Sugar_tr PF00083.24 OAP60721.1 - 1.4e-65 221.9 21.5 1.7e-65 221.6 21.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP60721.1 - 2.8e-21 75.8 27.8 1.2e-17 63.9 17.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily AA_permease_C PF13906.6 OAP60721.1 - 0.062 13.4 3.3 0.095 12.8 1.1 2.5 2 0 0 2 2 2 0 C-terminus of AA_permease zf-C2H2 PF00096.26 OAP60722.1 - 9.8e-06 25.8 11.9 0.00026 21.3 3.0 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OAP60722.1 - 3.8e-05 23.9 2.3 3.8e-05 23.9 2.3 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-met PF12874.7 OAP60722.1 - 9.8e-05 22.6 9.1 0.0011 19.2 1.1 2.6 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 OAP60722.1 - 0.0021 18.7 1.8 0.0021 18.7 1.8 2.7 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OAP60722.1 - 0.02 15.2 1.4 0.02 15.2 1.4 1.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 OAP60722.1 - 0.059 13.4 1.3 0.15 12.1 1.3 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger zf-Di19 PF05605.12 OAP60722.1 - 0.082 13.2 4.7 0.15 12.4 4.7 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding DUF1178 PF06676.11 OAP60722.1 - 1.7 9.0 7.8 0.11 12.9 2.8 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1178) Ceramidase_alk PF04734.13 OAP60724.1 - 0.29 9.7 0.1 0.36 9.4 0.1 1.1 1 0 0 1 1 1 0 Neutral/alkaline non-lysosomal ceramidase, N-terminal FAD_binding_3 PF01494.19 OAP60725.1 - 2.3e-22 79.7 0.0 4.3e-22 78.8 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 OAP60725.1 - 2.7e-08 33.4 0.6 7e-07 28.8 0.7 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAP60725.1 - 2.2e-06 27.5 2.9 4.9e-05 23.1 0.9 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OAP60725.1 - 2.3e-06 26.9 1.1 6.5e-06 25.5 1.1 1.7 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 OAP60725.1 - 1.1e-05 25.6 1.2 4.4e-05 23.6 1.2 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 OAP60725.1 - 5e-05 22.2 0.6 0.0051 15.6 0.4 2.1 2 0 0 2 2 2 2 HI0933-like protein Trp_halogenase PF04820.14 OAP60725.1 - 0.00024 20.1 0.3 0.012 14.5 0.2 2.5 2 1 0 3 3 3 1 Tryptophan halogenase Lycopene_cycl PF05834.12 OAP60725.1 - 0.0004 19.5 0.5 0.0012 18.0 0.0 1.9 2 1 0 2 2 2 1 Lycopene cyclase protein Pyr_redox PF00070.27 OAP60725.1 - 0.00053 20.5 1.3 0.019 15.5 2.4 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 OAP60725.1 - 0.0053 16.1 0.6 0.92 8.7 0.1 2.5 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase GIDA PF01134.22 OAP60725.1 - 0.0066 15.6 2.2 0.013 14.6 1.7 1.6 2 0 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.17 OAP60725.1 - 0.022 14.0 0.5 0.035 13.3 0.5 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 OAP60725.1 - 0.073 12.3 0.1 0.29 10.3 0.1 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 OAP60725.1 - 0.11 12.4 1.1 0.19 11.6 1.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.6 OAP60725.1 - 0.24 11.4 1.8 3.9 7.5 0.9 2.8 2 1 0 2 2 2 0 FAD-NAD(P)-binding FAD_oxidored PF12831.7 OAP60725.1 - 0.27 10.5 4.2 0.13 11.6 0.9 2.1 4 0 0 4 4 4 0 FAD dependent oxidoreductase bZIP_1 PF00170.21 OAP60726.1 - 0.0035 17.4 18.2 1 9.5 15.6 2.2 1 1 1 2 2 2 2 bZIP transcription factor GIT_CC PF16559.5 OAP60726.1 - 0.028 14.3 1.7 0.054 13.4 1.7 1.4 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor bZIP_2 PF07716.15 OAP60726.1 - 0.06 13.4 16.6 0.64 10.1 15.3 2.2 1 1 1 2 2 2 0 Basic region leucine zipper V_ATPase_I_N PF18670.1 OAP60726.1 - 0.068 13.6 0.4 0.13 12.7 0.4 1.4 1 0 0 1 1 1 0 V-type ATPase subunit I, N-terminal domain bZIP_Maf PF03131.17 OAP60726.1 - 0.078 13.5 15.7 0.13 12.8 15.7 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor YabA PF06156.13 OAP60726.1 - 0.14 12.8 0.5 0.14 12.8 0.5 1.7 1 1 1 2 2 2 0 Initiation control protein YabA DUF2205 PF10224.9 OAP60726.1 - 0.16 11.9 2.2 0.27 11.2 2.2 1.3 1 0 0 1 1 1 0 Short coiled-coil protein Methyltransf_23 PF13489.6 OAP60727.1 - 2.7e-12 46.8 0.0 3.7e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAP60727.1 - 3.6e-08 34.0 0.0 1e-07 32.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAP60727.1 - 1.5e-06 28.9 0.0 2.6e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAP60727.1 - 2.5e-05 24.1 0.0 5.1e-05 23.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAP60727.1 - 8.5e-05 23.2 0.0 0.0021 18.7 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain DREV PF05219.12 OAP60727.1 - 0.17 11.0 0.0 15 4.6 0.0 2.1 2 0 0 2 2 2 0 DREV methyltransferase Ubie_methyltran PF01209.18 OAP60727.1 - 0.17 11.2 0.0 0.31 10.3 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family SLAC1 PF03595.17 OAP60728.1 - 4.9e-99 331.7 54.2 5.6e-99 331.5 54.2 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel DUF3481 PF11980.8 OAP60728.1 - 0.061 13.0 0.1 0.47 10.2 0.0 2.2 2 0 0 2 2 2 0 C-terminal domain of neuropilin glycoprotein CemA PF03040.14 OAP60728.1 - 0.065 13.2 0.4 5.7 6.8 0.2 2.5 2 0 0 2 2 2 0 CemA family K1 PF02960.14 OAP60728.1 - 0.081 13.0 0.3 0.23 11.6 0.0 1.9 2 0 0 2 2 2 0 K1 glycoprotein Oxidored_molyb PF00174.19 OAP60729.1 - 1.4e-57 194.0 0.0 2.6e-57 193.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 OAP60729.1 - 4.7e-24 85.0 0.0 1.1e-23 83.8 0.0 1.6 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Cyt-b5 PF00173.28 OAP60729.1 - 7.2e-10 38.9 0.0 1.3e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Amidase PF01425.21 OAP60730.1 - 1.2e-79 268.4 0.0 1.9e-79 267.8 0.0 1.3 1 1 0 1 1 1 1 Amidase Zn_clus PF00172.18 OAP60731.1 - 3e-05 24.0 14.9 5e-05 23.3 14.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1556 PF07590.11 OAP60731.1 - 2.5 8.5 9.5 0.13 12.5 1.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1556) Rpp20 PF12328.8 OAP60732.1 - 1.9e-29 102.4 9.2 3.7e-28 98.2 9.2 2.2 1 1 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.21 OAP60732.1 - 6.5e-13 48.3 0.1 1.3e-11 44.1 0.1 2.2 1 1 0 1 1 1 1 Alba LZ_Tnp_IS66 PF13007.7 OAP60732.1 - 1.2 10.0 5.2 0.55 11.1 0.7 2.5 2 0 0 2 2 2 0 Transposase C of IS166 homeodomain Metallophos_2 PF12850.7 OAP60733.1 - 4.7e-13 49.7 0.0 5.9e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain TFIIF_beta PF02270.15 OAP60735.1 - 8.7e-27 93.1 0.5 1.5e-26 92.3 0.5 1.4 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain TFIIF_beta_N PF17683.1 OAP60735.1 - 2.1e-24 86.7 0.2 1.1e-23 84.4 0.0 2.0 2 0 0 2 2 2 1 TFIIF, beta subunit N-terminus Tau95 PF09734.9 OAP60735.1 - 0.00014 22.6 0.6 0.00028 21.7 0.6 1.7 1 1 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain 2-Hacid_dh_C PF02826.19 OAP60736.1 - 2.9e-56 189.6 0.0 4e-56 189.2 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 OAP60736.1 - 7e-13 48.4 0.0 8.6e-13 48.1 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 OAP60736.1 - 7e-05 23.0 0.0 0.00011 22.4 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 OAP60736.1 - 0.042 13.4 0.0 0.061 12.9 0.0 1.2 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain CTP_transf_like PF01467.26 OAP60738.1 - 8.7e-26 90.8 0.0 2.5e-22 79.6 0.0 2.3 2 0 0 2 2 2 2 Cytidylyltransferase-like Glutaredoxin PF00462.24 OAP60740.1 - 4.4e-09 36.4 0.1 2.2e-07 31.0 0.1 2.7 1 1 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.6 OAP60740.1 - 0.0083 16.5 0.1 0.09 13.2 0.1 2.2 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Zn_clus PF00172.18 OAP60741.1 - 1.4e-08 34.7 9.9 2.3e-08 34.0 9.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-U1 PF06220.12 OAP60742.1 - 4.4e-11 42.4 0.3 7.4e-11 41.6 0.3 1.4 1 0 0 1 1 1 1 U1 zinc finger DUF3896 PF13035.6 OAP60742.1 - 0.49 10.6 2.8 0.86 9.8 1.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3896) PRELI PF04707.14 OAP60743.1 - 2.3e-43 147.7 0.4 2.6e-43 147.5 0.4 1.0 1 0 0 1 1 1 1 PRELI-like family GATase_3 PF07685.14 OAP60743.1 - 0.11 12.1 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain Abhydrolase_6 PF12697.7 OAP60744.1 - 3.9e-09 37.5 6.2 1.2e-07 32.6 3.6 2.8 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAP60744.1 - 2.3e-08 34.0 0.0 6.5e-08 32.5 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAP60744.1 - 0.0028 16.9 0.0 0.02 14.2 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Acetyltransf_7 PF13508.7 OAP60746.1 - 2.9e-08 34.0 0.0 6.3e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OAP60746.1 - 1.1e-06 28.6 0.0 0.00061 19.7 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAP60746.1 - 2.9e-06 27.5 0.0 9.9e-06 25.8 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_CG PF14542.6 OAP60746.1 - 0.00026 21.1 0.0 0.00054 20.0 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 OAP60746.1 - 0.0063 16.5 0.0 0.26 11.3 0.0 2.3 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_9 PF13527.7 OAP60746.1 - 0.048 13.7 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 OAP60746.1 - 0.074 12.5 0.0 1.2 8.5 0.0 2.1 2 0 0 2 2 2 0 Putative acetyl-transferase CDC45 PF02724.14 OAP60746.1 - 1.8 6.8 3.4 2.4 6.3 3.4 1.2 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 OAP60746.1 - 3.1 7.1 9.3 4.6 6.6 9.3 1.2 1 0 0 1 1 1 0 SDA1 GST_N_3 PF13417.6 OAP60747.1 - 9.7e-15 54.8 0.0 2.1e-14 53.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OAP60747.1 - 4.7e-13 49.2 0.0 1.3e-12 47.9 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 OAP60747.1 - 4.2e-10 39.8 0.0 9.4e-10 38.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAP60747.1 - 5.2e-07 29.6 0.1 1.1e-06 28.5 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 OAP60747.1 - 0.00032 21.2 0.0 0.00068 20.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain TFIIA PF03153.13 OAP60747.1 - 0.015 15.4 15.4 0.027 14.5 15.4 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit GST_C_3 PF14497.6 OAP60747.1 - 0.11 12.7 0.0 0.36 11.0 0.0 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain RbpA PF13397.6 OAP60747.1 - 0.34 11.5 1.5 3.2 8.4 0.1 2.5 2 0 0 2 2 2 0 RNA polymerase-binding protein Pkinase PF00069.25 OAP60749.1 - 6.4e-56 189.6 0.1 1.1e-39 136.4 0.2 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAP60749.1 - 2.6e-26 92.5 0.2 1.4e-19 70.4 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 OAP60749.1 - 3.3e-06 26.3 0.1 5e-06 25.7 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OAP60749.1 - 0.00041 20.3 0.1 0.063 13.2 0.2 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 OAP60749.1 - 0.00066 19.1 0.0 0.0018 17.7 0.0 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OAP60749.1 - 0.0017 17.8 0.0 0.0046 16.3 0.0 1.7 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 OAP60749.1 - 0.031 13.9 0.1 7.3 6.1 0.0 2.5 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Seadorna_VP7 PF07387.11 OAP60749.1 - 0.031 13.3 0.0 0.052 12.6 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.22 OAP60749.1 - 0.069 12.7 1.1 1.3 8.6 0.0 2.3 2 0 0 2 2 2 0 RIO1 family PA28_alpha PF02251.18 OAP60749.1 - 0.073 13.1 0.3 0.87 9.7 0.0 2.7 3 0 0 3 3 3 0 Proteasome activator pa28 alpha subunit SpoIIIAH PF12685.7 OAP60749.1 - 0.79 9.5 4.4 1.7 8.4 4.4 1.5 1 1 0 1 1 1 0 SpoIIIAH-like protein Tim54 PF11711.8 OAP60750.1 - 8.9e-144 478.9 0.2 1e-143 478.7 0.2 1.0 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 CAP_GLY PF01302.25 OAP60751.1 - 4e-15 55.6 0.0 7e-15 54.8 0.0 1.3 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.7 OAP60751.1 - 3.4e-11 43.2 22.8 2.5e-05 24.5 1.5 5.2 5 0 0 5 5 5 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 OAP60751.1 - 2.3e-09 37.0 0.1 0.0016 18.0 0.0 2.7 3 0 0 3 3 3 2 Leucine-rich repeat LRR_8 PF13855.6 OAP60751.1 - 7.6e-06 25.6 15.3 0.029 14.1 1.0 4.7 3 1 2 5 5 5 3 Leucine rich repeat LRR_6 PF13516.6 OAP60751.1 - 0.00035 20.4 15.6 0.47 10.6 0.6 6.7 7 0 0 7 7 7 3 Leucine Rich repeat LRR_1 PF00560.33 OAP60751.1 - 0.0011 19.2 12.9 21 6.2 0.1 7.5 7 0 0 7 7 7 1 Leucine Rich Repeat LRR_2 PF07723.13 OAP60751.1 - 0.011 16.4 6.1 1.1 10.0 0.2 4.3 3 0 0 3 3 3 0 Leucine Rich Repeat Dna2 PF08696.11 OAP60752.1 - 7.5e-63 212.0 0.0 1.9e-62 210.7 0.0 1.7 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_12 PF13087.6 OAP60752.1 - 1.9e-51 174.5 0.0 3.2e-51 173.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 OAP60752.1 - 1.5e-32 113.5 0.3 4.8e-16 59.3 0.0 3.1 2 1 1 3 3 3 2 AAA domain AAA_30 PF13604.6 OAP60752.1 - 1.1e-16 61.2 0.0 2.3e-16 60.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OAP60752.1 - 1.3e-12 48.3 0.9 2.6e-12 47.3 0.0 2.0 2 0 0 2 2 1 1 AAA domain Cas_Cas4 PF01930.17 OAP60752.1 - 1e-08 35.5 1.7 5e-08 33.2 1.1 2.2 2 0 0 2 2 2 1 Domain of unknown function DUF83 Viral_helicase1 PF01443.18 OAP60752.1 - 7.5e-05 22.6 3.6 0.38 10.5 0.1 3.7 4 0 0 4 4 3 2 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.21 OAP60752.1 - 0.00026 20.6 0.0 0.00083 19.0 0.0 1.9 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain SRP54 PF00448.22 OAP60752.1 - 0.00055 19.6 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_16 PF13191.6 OAP60752.1 - 0.0014 19.0 0.4 0.024 15.0 0.0 3.1 4 0 0 4 4 4 1 AAA ATPase domain Helicase_RecD PF05127.14 OAP60752.1 - 0.0016 18.3 0.0 0.0058 16.5 0.0 2.0 1 1 0 1 1 1 1 Helicase TFIIA PF03153.13 OAP60752.1 - 0.0034 17.4 15.1 0.043 13.8 14.6 2.9 3 1 0 3 3 2 1 Transcription factor IIA, alpha/beta subunit CbiA PF01656.23 OAP60752.1 - 0.0086 16.1 0.0 0.02 14.9 0.0 1.7 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain DNA_mis_repair PF01119.19 OAP60752.1 - 0.0098 15.6 0.0 3 7.5 0.0 2.5 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain ResIII PF04851.15 OAP60752.1 - 0.021 14.8 0.0 0.056 13.4 0.0 1.8 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_7 PF12775.7 OAP60752.1 - 0.03 13.9 0.1 0.071 12.6 0.1 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region T2SSE PF00437.20 OAP60752.1 - 0.03 13.4 0.2 0.3 10.1 0.1 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein PIF1 PF05970.14 OAP60752.1 - 0.043 13.0 0.1 0.29 10.3 0.0 2.0 2 0 0 2 2 2 0 PIF1-like helicase DUF87 PF01935.17 OAP60752.1 - 0.049 13.7 0.9 0.16 12.1 0.2 2.3 2 0 0 2 2 1 0 Helicase HerA, central domain cobW PF02492.19 OAP60752.1 - 0.069 12.7 0.1 0.16 11.6 0.1 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.6 OAP60752.1 - 0.1 12.2 0.0 0.43 10.1 0.0 2.0 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 OAP60752.1 - 0.11 12.4 0.2 0.27 11.2 0.2 1.6 1 0 0 1 1 1 0 NTPase AAA_18 PF13238.6 OAP60752.1 - 0.11 13.0 0.0 0.35 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 OAP60752.1 - 0.12 12.8 0.0 0.45 10.9 0.0 2.0 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 OAP60752.1 - 0.13 11.5 0.0 0.26 10.5 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) MeaB PF03308.16 OAP60752.1 - 0.15 11.0 0.0 0.27 10.2 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB SIR2 PF02146.17 OAP60753.1 - 2.6e-43 148.0 0.0 1.9e-31 109.3 0.0 2.3 2 0 0 2 2 2 2 Sir2 family DUF592 PF04574.13 OAP60753.1 - 4e-05 23.4 0.0 7.1e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF592) Mito_carr PF00153.27 OAP60754.1 - 9.7e-66 217.8 0.4 5.3e-22 77.6 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein HLH PF00010.26 OAP60755.1 - 1.7e-11 43.9 0.0 8e-11 41.7 0.0 2.0 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain Got1 PF04178.12 OAP60756.1 - 2.9e-36 124.3 15.1 3.8e-36 123.9 15.1 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family Ank_5 PF13857.6 OAP60757.1 - 1.5e-09 37.9 0.4 2.8e-08 33.9 0.1 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 OAP60757.1 - 7.4e-08 32.8 0.1 4.8e-07 30.2 0.1 2.2 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 OAP60757.1 - 1.4e-06 28.8 0.1 2.4e-06 28.0 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OAP60757.1 - 6.8e-06 26.0 1.4 4.5e-05 23.5 0.1 2.9 3 1 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 OAP60757.1 - 0.0014 18.9 0.1 0.009 16.4 0.1 2.2 2 0 0 2 2 2 1 Ankyrin repeat DUF1741 PF08427.10 OAP60757.1 - 0.079 12.6 0.0 0.51 9.9 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1741) RNA_lig_T4_1 PF09511.10 OAP60758.1 - 3e-88 295.4 0.0 6.9e-88 294.2 0.0 1.6 1 0 0 1 1 1 1 RNA ligase tRNA_lig_CPD PF08302.11 OAP60758.1 - 8.3e-80 267.9 0.0 1.3e-79 267.3 0.0 1.3 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain tRNA_lig_kinase PF08303.11 OAP60758.1 - 7.2e-49 166.1 0.2 1.3e-48 165.2 0.2 1.5 1 0 0 1 1 1 1 tRNA ligase kinase domain AAA_18 PF13238.6 OAP60758.1 - 0.00096 19.7 0.1 0.033 14.7 0.0 3.2 3 0 0 3 3 3 1 AAA domain RNA_ligase PF09414.10 OAP60758.1 - 0.0054 17.1 0.0 0.012 15.9 0.0 1.6 1 0 0 1 1 1 1 RNA ligase Cyclin_N PF00134.23 OAP60759.1 - 4.9e-46 155.6 0.0 1.1e-44 151.3 0.0 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 OAP60759.1 - 2.2e-32 111.6 0.0 5.1e-32 110.5 0.0 1.7 1 0 0 1 1 1 1 Cyclin, C-terminal domain HIT PF01230.23 OAP60760.1 - 2.5e-19 69.8 0.1 3.9e-19 69.2 0.1 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 OAP60760.1 - 1.5e-05 25.5 0.2 3.9e-05 24.1 0.0 1.7 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 OAP60760.1 - 0.17 11.8 0.4 0.44 10.4 0.4 1.9 1 1 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 UPF0020 PF01170.18 OAP60761.1 - 1.3e-08 34.8 0.0 0.00015 21.5 0.1 2.3 2 0 0 2 2 2 2 Putative RNA methylase family UPF0020 N6_N4_Mtase PF01555.18 OAP60761.1 - 0.0014 18.4 0.0 0.013 15.2 0.0 2.3 3 0 0 3 3 3 1 DNA methylase RWD PF05773.22 OAP60762.1 - 2.5e-23 82.6 0.1 4.2e-23 81.8 0.1 1.4 1 0 0 1 1 1 1 RWD domain DFRP_C PF16543.5 OAP60762.1 - 0.13 12.8 12.0 0.21 12.1 11.1 1.7 1 1 0 1 1 1 0 DRG Family Regulatory Proteins, Tma46 Mpp10 PF04006.12 OAP60763.1 - 4.6e-107 359.0 53.5 4.5e-106 355.7 53.5 2.3 1 1 0 1 1 1 1 Mpp10 protein SPX PF03105.19 OAP60764.1 - 2.9e-07 30.8 29.7 0.0023 17.9 0.4 4.9 2 2 2 4 4 4 3 SPX domain VTC PF09359.10 OAP60764.1 - 0.00042 19.8 0.1 0.34 10.3 0.0 2.6 1 1 1 2 2 2 2 VTC domain Voltage_CLC PF00654.20 OAP60765.1 - 2.3e-87 293.5 19.5 2.3e-87 293.5 19.5 1.7 2 0 0 2 2 2 1 Voltage gated chloride channel PDR_assoc PF08370.11 OAP60765.1 - 0.05 13.4 2.9 0.091 12.5 1.0 2.3 2 0 0 2 2 2 0 Plant PDR ABC transporter associated Sulfate_transp PF00916.20 OAP60766.1 - 4.3e-63 213.4 20.3 6.8e-63 212.7 20.3 1.2 1 0 0 1 1 1 1 Sulfate permease family cNMP_binding PF00027.29 OAP60766.1 - 1.2e-14 54.1 0.0 2.2e-14 53.3 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.21 OAP60766.1 - 1.7e-13 50.3 0.1 2.9e-13 49.5 0.1 1.4 1 0 0 1 1 1 1 STAS domain PH_6 PF15406.6 OAP60767.1 - 2.8e-33 114.5 4.2 2.8e-33 114.5 4.2 3.5 4 0 0 4 4 4 1 Pleckstrin homology domain PH PF00169.29 OAP60767.1 - 6e-06 26.7 0.1 6.5e-05 23.4 0.0 2.6 2 1 0 2 2 2 1 PH domain bZIP_2 PF07716.15 OAP60768.1 - 3.1e-08 33.6 7.0 5.2e-08 32.9 7.0 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 OAP60768.1 - 0.0013 18.7 6.3 0.0025 17.9 6.3 1.3 1 0 0 1 1 1 1 bZIP transcription factor RR_TM4-6 PF06459.12 OAP60768.1 - 0.46 10.3 4.5 0.57 10.0 4.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 U1snRNP70_N PF12220.8 OAP60768.1 - 1.4 9.6 6.9 2.6 8.7 6.9 1.4 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Presenilin PF01080.17 OAP60768.1 - 9.6 4.8 5.5 12 4.5 5.5 1.1 1 0 0 1 1 1 0 Presenilin zf-H2C2_2 PF13465.6 OAP60769.1 - 2.3e-08 34.1 5.9 6e-06 26.5 0.6 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 OAP60769.1 - 1.2e-07 31.7 5.4 1.3e-05 25.4 0.2 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 OAP60769.1 - 4.8e-05 23.2 0.7 0.014 15.4 0.0 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_4 PF13894.6 OAP60769.1 - 0.00035 21.2 6.2 0.008 16.9 0.2 2.9 3 0 0 3 3 3 2 C2H2-type zinc finger FOXP-CC PF16159.5 OAP60769.1 - 0.0045 17.6 9.8 0.11 13.1 0.1 3.6 2 1 2 4 4 4 2 FOXP coiled-coil domain zf-H2C2_5 PF13909.6 OAP60769.1 - 0.059 13.1 1.4 0.79 9.5 0.1 2.5 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-met PF12874.7 OAP60769.1 - 0.068 13.6 0.3 15 6.1 0.0 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type SOGA PF11365.8 OAP60769.1 - 0.074 14.2 0.1 0.21 12.8 0.1 1.7 1 0 0 1 1 1 0 Protein SOGA zf-C2H2_11 PF16622.5 OAP60769.1 - 0.086 12.6 0.6 0.71 9.7 0.0 2.2 2 0 0 2 2 2 0 zinc-finger C2H2-type Sina PF03145.16 OAP60769.1 - 0.22 11.4 5.0 6 6.8 0.6 2.2 1 1 1 2 2 2 0 Seven in absentia protein family FAD_binding_3 PF01494.19 OAP60770.1 - 2.7e-25 89.4 0.6 1.7e-24 86.8 0.6 1.9 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAP60770.1 - 4.4e-13 49.6 5.3 1.2e-05 25.0 1.4 3.1 1 1 1 3 3 3 3 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAP60770.1 - 3e-09 36.5 0.1 0.00096 18.5 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 OAP60770.1 - 3.8e-07 29.3 1.0 0.02 13.8 0.0 2.8 3 0 0 3 3 3 2 Tryptophan halogenase Pyr_redox_3 PF13738.6 OAP60770.1 - 1.1e-05 24.8 0.4 0.0049 16.2 0.2 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OAP60770.1 - 1.2e-05 24.6 0.8 0.043 12.9 0.2 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein NAD_binding_8 PF13450.6 OAP60770.1 - 7.1e-05 23.0 1.7 7.8e-05 22.8 0.0 1.9 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 OAP60770.1 - 0.00017 20.4 0.6 0.0015 17.3 0.6 2.0 1 1 0 1 1 1 1 HI0933-like protein Amino_oxidase PF01593.24 OAP60770.1 - 0.00072 19.0 0.9 0.12 11.6 0.0 2.8 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 OAP60770.1 - 0.0019 17.3 0.9 0.0037 16.4 0.9 1.5 1 0 0 1 1 1 1 FAD binding domain SE PF08491.10 OAP60770.1 - 0.0069 15.5 0.0 0.51 9.3 0.0 2.3 2 0 0 2 2 2 1 Squalene epoxidase Pyr_redox PF00070.27 OAP60770.1 - 0.0076 16.8 0.4 3.8 8.1 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAP60770.1 - 0.013 14.7 0.2 0.022 14.0 0.2 1.3 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.6 OAP60770.1 - 0.036 14.1 3.2 0.74 9.8 0.1 3.1 3 1 0 3 3 3 0 FAD-NAD(P)-binding MCRA PF06100.11 OAP60770.1 - 0.12 11.2 0.5 0.24 10.1 0.5 1.5 1 0 0 1 1 1 0 MCRA family K_oxygenase PF13434.6 OAP60770.1 - 0.18 10.9 0.1 4.4 6.4 0.1 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) tRNA_SAD PF07973.14 OAP60771.1 - 2e-06 27.8 0.8 3.3e-06 27.1 0.8 1.4 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain tRNA-synt_2c PF01411.19 OAP60771.1 - 4.2e-06 25.6 0.0 5.3e-06 25.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) 6PGD PF00393.19 OAP60772.1 - 3.4e-89 299.1 0.0 4.2e-89 298.7 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 OAP60772.1 - 4.8e-33 114.6 0.0 1.8e-32 112.7 0.0 1.9 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 OAP60772.1 - 2.5e-05 24.2 0.0 4.9e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 OAP60772.1 - 0.00031 20.1 0.1 0.0014 18.0 0.0 1.9 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 OAP60772.1 - 0.00098 19.4 0.0 0.022 15.0 0.0 2.4 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain NAD_Gly3P_dh_N PF01210.23 OAP60772.1 - 0.0023 17.9 0.0 0.007 16.4 0.0 1.8 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UDPG_MGDP_dh_N PF03721.14 OAP60772.1 - 0.0031 17.1 0.0 0.0061 16.2 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.16 OAP60772.1 - 0.0073 16.0 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 OAP60772.1 - 0.056 14.0 0.0 0.17 12.5 0.0 1.9 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent AP_endonuc_2 PF01261.24 OAP60773.1 - 2e-37 128.7 0.0 2.9e-37 128.2 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel MFS_1 PF07690.16 OAP60774.1 - 8.7e-36 123.6 60.5 4.3e-35 121.3 58.1 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily AgrB PF04647.15 OAP60774.1 - 0.056 12.7 2.3 0.25 10.6 2.3 2.2 1 0 0 1 1 1 0 Accessory gene regulator B Sec2p PF06428.11 OAP60775.1 - 0.004 17.1 2.1 0.0056 16.6 2.1 1.2 1 0 0 1 1 1 1 GDP/GTP exchange factor Sec2p APG6_N PF17675.1 OAP60775.1 - 0.0051 17.3 3.8 0.0062 17.1 3.8 1.1 1 0 0 1 1 1 1 Apg6 coiled-coil region Mod_r PF07200.13 OAP60775.1 - 0.015 15.4 3.1 0.018 15.1 3.1 1.1 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein HALZ PF02183.18 OAP60775.1 - 0.015 15.5 0.6 0.031 14.5 0.6 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper ZapB PF06005.12 OAP60775.1 - 0.038 14.4 3.7 0.058 13.8 3.7 1.4 1 0 0 1 1 1 0 Cell division protein ZapB Atg14 PF10186.9 OAP60775.1 - 0.082 12.0 5.3 0.09 11.8 5.3 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF5082 PF16888.5 OAP60775.1 - 0.089 13.1 3.8 0.1 12.9 3.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) SUIM_assoc PF16619.5 OAP60775.1 - 0.15 12.1 3.7 0.34 11.0 3.7 1.6 1 1 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Spc7 PF08317.11 OAP60775.1 - 0.21 10.4 5.8 0.26 10.2 5.8 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein HCMV_UL139 PF12507.8 OAP60775.1 - 0.25 11.7 6.6 0.64 10.4 6.6 1.6 1 1 0 1 1 1 0 Human Cytomegalovirus UL139 protein DUF4407 PF14362.6 OAP60775.1 - 0.25 10.6 3.3 0.32 10.3 3.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CENP-H PF05837.12 OAP60775.1 - 0.46 10.9 5.8 0.6 10.5 5.8 1.1 1 0 0 1 1 1 0 Centromere protein H (CENP-H) FlxA PF14282.6 OAP60775.1 - 1 9.4 5.1 1.5 8.8 5.1 1.3 1 1 0 1 1 1 0 FlxA-like protein DUF4140 PF13600.6 OAP60775.1 - 3.1 8.3 7.7 11 6.6 7.7 1.9 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DivIC PF04977.15 OAP60775.1 - 3.1 7.6 8.9 3.9 7.3 5.8 2.1 1 1 1 2 2 2 0 Septum formation initiator Adenylsucc_synt PF00709.21 OAP60776.1 - 5.2e-165 549.4 0.0 6.2e-165 549.2 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase CFEM PF05730.11 OAP60777.1 - 0.19 11.8 4.3 0.22 11.6 0.8 2.2 2 0 0 2 2 2 0 CFEM domain DUF21 PF01595.20 OAP60777.1 - 0.73 9.5 5.2 1.3 8.7 5.2 1.5 1 0 0 1 1 1 0 Cyclin M transmembrane N-terminal domain PRK PF00485.18 OAP60778.1 - 6.9e-05 22.7 0.0 0.00033 20.5 0.0 1.9 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family NB-ARC PF00931.22 OAP60778.1 - 0.00012 21.3 0.0 0.00026 20.3 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain AAA_33 PF13671.6 OAP60778.1 - 0.00054 20.1 0.0 0.047 13.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 OAP60778.1 - 0.0011 18.9 0.0 0.0019 18.1 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 OAP60778.1 - 0.003 17.9 0.1 0.043 14.2 0.0 2.2 1 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 OAP60778.1 - 0.0045 17.3 0.0 0.029 14.6 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA PF00004.29 OAP60778.1 - 0.0045 17.4 0.0 0.0087 16.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Thymidylate_kin PF02223.17 OAP60778.1 - 0.0063 16.2 0.2 0.83 9.3 0.0 2.5 3 0 0 3 3 2 1 Thymidylate kinase AAA_18 PF13238.6 OAP60778.1 - 0.01 16.4 2.6 0.022 15.3 0.1 2.6 1 1 1 2 2 2 0 AAA domain AAA_17 PF13207.6 OAP60778.1 - 0.027 14.9 2.7 0.07 13.5 0.1 2.6 1 1 1 3 3 3 0 AAA domain Viral_helicase1 PF01443.18 OAP60778.1 - 0.054 13.2 0.0 0.087 12.6 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase cobW PF02492.19 OAP60778.1 - 0.058 13.0 0.1 0.1 12.2 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Ploopntkinase3 PF18751.1 OAP60778.1 - 0.06 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 T2SSE PF00437.20 OAP60778.1 - 0.065 12.3 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_19 PF13245.6 OAP60778.1 - 0.088 13.1 0.0 0.13 12.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 OAP60778.1 - 0.091 12.7 0.1 0.16 11.9 0.1 1.4 1 0 0 1 1 1 0 NTPase AAA_30 PF13604.6 OAP60778.1 - 0.11 12.2 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 OAP60778.1 - 0.17 11.9 0.0 0.29 11.2 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_23 PF13476.6 OAP60778.1 - 0.23 12.0 2.6 0.57 10.7 2.6 1.8 1 1 0 1 1 1 0 AAA domain MBOAT_2 PF13813.6 OAP60780.1 - 1.2e-19 70.3 3.2 3.3e-19 68.9 3.2 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Pkinase PF00069.25 OAP60781.1 - 1.6e-72 244.1 0.0 4.9e-72 242.5 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP60781.1 - 4.3e-50 170.4 0.0 7.5e-50 169.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAP60781.1 - 0.0019 17.1 0.0 0.0037 16.1 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase GerD PF17898.1 OAP60781.1 - 0.011 15.6 1.0 0.045 13.7 0.5 2.3 2 0 0 2 2 2 0 Spore germination GerD central core domain DUF383 PF04063.14 OAP60781.1 - 0.014 15.1 1.6 0.091 12.4 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF383) Kinase-like PF14531.6 OAP60781.1 - 0.029 13.7 0.0 0.16 11.3 0.0 2.0 2 0 0 2 2 2 0 Kinase-like CLASP_N PF12348.8 OAP60781.1 - 0.051 13.1 4.1 2.9 7.4 1.0 2.5 2 0 0 2 2 2 0 CLASP N terminal Arfaptin PF06456.13 OAP60781.1 - 0.085 12.4 0.0 0.21 11.1 0.0 1.6 1 0 0 1 1 1 0 Arfaptin-like domain UTP15_C PF09384.10 OAP60781.1 - 0.99 9.1 3.9 2 8.1 0.8 2.5 3 0 0 3 3 3 0 UTP15 C terminal DUF3425 PF11905.8 OAP60783.1 - 3e-17 62.8 1.5 1e-16 61.1 1.5 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) VPS9 PF02204.18 OAP60784.1 - 1.8e-29 102.0 0.0 2.9e-29 101.3 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 OAP60784.1 - 2.6e-14 53.2 0.1 6.5e-14 52.0 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF5601) CUE PF02845.16 OAP60784.1 - 1.7e-08 34.0 0.2 1.6e-07 30.9 0.0 2.3 2 0 0 2 2 2 1 CUE domain Asn_synthase PF00733.21 OAP60785.1 - 1e-15 58.3 0.6 9.1e-10 38.7 0.3 3.2 2 1 0 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 OAP60785.1 - 6.3e-07 29.3 0.0 1.5e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 OAP60785.1 - 0.00019 21.7 0.0 0.00065 19.9 0.0 1.8 1 1 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 OAP60785.1 - 0.0065 16.0 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein MFS_1 PF07690.16 OAP60786.1 - 5e-37 127.6 75.9 1.5e-33 116.2 48.0 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAP60786.1 - 2.1e-05 23.6 33.7 0.0032 16.4 10.9 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 OAP60787.1 - 8.8e-22 77.5 56.3 2e-21 76.4 37.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3367 PF11847.8 OAP60787.1 - 1.4 6.7 7.5 0.054 11.4 0.6 1.8 2 0 0 2 2 2 0 Alpha-(1->3)-arabinofuranosyltransferase RRM_1 PF00076.22 OAP60788.1 - 4.1e-13 49.0 0.0 6.4e-13 48.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF812 PF05667.11 OAP60788.1 - 0.71 8.7 5.8 0.9 8.3 5.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Sin_N PF04801.13 OAP60788.1 - 2.2 7.4 5.1 2.8 7.1 5.1 1.0 1 0 0 1 1 1 0 Sin-like protein conserved region HECT PF00632.25 OAP60789.1 - 3.3e-99 332.2 0.0 4.7e-99 331.7 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 OAP60789.1 - 9.1e-34 115.2 20.2 1.2e-11 44.5 1.4 4.0 4 0 0 4 4 4 3 WW domain C2 PF00168.30 OAP60789.1 - 5.1e-20 71.7 0.0 1.2e-19 70.5 0.0 1.6 1 0 0 1 1 1 1 C2 domain Clr5 PF14420.6 OAP60790.1 - 0.0018 18.5 0.0 0.0037 17.4 0.0 1.5 1 0 0 1 1 1 1 Clr5 domain LSM PF01423.22 OAP60791.1 - 6.9e-18 64.1 0.1 1e-17 63.5 0.1 1.3 1 0 0 1 1 1 1 LSM domain MFS_1 PF07690.16 OAP60792.1 - 3.3e-28 98.6 34.1 3.5e-28 98.5 33.2 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF2530 PF10745.9 OAP60792.1 - 8 6.8 15.6 0.23 11.7 1.0 4.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2530) Alpha-amylase PF00128.24 OAP60793.1 - 1.7e-107 359.9 0.1 3.1e-107 359.1 0.0 1.4 2 0 0 2 2 2 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 OAP60793.1 - 2.7e-09 37.0 0.0 5.4e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain hDGE_amylase PF14701.6 OAP60793.1 - 0.00042 19.5 0.0 0.00073 18.7 0.0 1.3 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain Glyco_hydro_42C PF08533.10 OAP60793.1 - 0.015 15.0 0.2 0.058 13.1 0.0 2.1 2 0 0 2 2 2 0 Beta-galactosidase C-terminal domain FAA_hydrolase PF01557.18 OAP60794.1 - 2.1e-51 174.7 0.0 2.8e-51 174.3 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 OAP60794.1 - 2.3e-32 111.3 0.0 3.8e-32 110.6 0.0 1.4 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal p450 PF00067.22 OAP60795.1 - 7.6e-60 203.0 0.0 8.6e-60 202.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HgmA PF04209.13 OAP60796.1 - 3.5e-194 645.4 0.3 4e-194 645.2 0.3 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase HLH PF00010.26 OAP60797.1 - 7e-12 45.1 0.0 1.2e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PPP4R2 PF09184.11 OAP60797.1 - 0.0047 16.6 2.8 0.0087 15.7 2.8 1.5 1 1 0 1 1 1 1 PPP4R2 DUF4611 PF15387.6 OAP60797.1 - 0.012 15.8 1.9 0.012 15.8 1.9 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) NOA36 PF06524.12 OAP60797.1 - 0.063 12.6 4.4 0.095 12.0 4.4 1.2 1 0 0 1 1 1 0 NOA36 protein RXT2_N PF08595.11 OAP60797.1 - 0.073 13.1 1.0 0.16 12.0 1.0 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal CENP-B_dimeris PF09026.10 OAP60797.1 - 0.098 13.1 14.1 0.19 12.1 14.1 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain FAM176 PF14851.6 OAP60797.1 - 0.18 11.5 1.4 0.4 10.3 1.4 1.5 1 0 0 1 1 1 0 FAM176 family PI3K_1B_p101 PF10486.9 OAP60797.1 - 0.22 9.3 2.3 0.39 8.5 2.3 1.3 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Macoilin PF09726.9 OAP60797.1 - 0.81 8.2 5.7 1.3 7.5 5.7 1.4 1 0 0 1 1 1 0 Macoilin family DNA_pol_phi PF04931.13 OAP60797.1 - 1.5 6.8 8.1 2.1 6.3 8.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi PBP1_TM PF14812.6 OAP60797.1 - 6.2 7.3 13.0 0.21 12.0 6.2 1.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Aminotran_4 PF01063.19 OAP60798.1 - 3.2e-30 105.7 0.0 4e-30 105.4 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV Pkinase_Tyr PF07714.17 OAP60799.1 - 8.6e-13 48.2 0.0 6.2e-11 42.1 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OAP60799.1 - 5.1e-10 39.2 0.0 2.2e-09 37.1 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 OAP60799.1 - 0.2 11.0 0.0 0.33 10.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 OAP60800.1 - 4.3e-18 65.6 0.0 2.2e-17 63.3 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP60800.1 - 1.6e-09 37.4 0.0 1.7e-08 34.1 0.0 2.3 2 1 0 2 2 2 1 Protein tyrosine kinase MIP PF00230.20 OAP60801.1 - 7.9e-44 150.1 10.8 1.7e-43 148.9 10.8 1.5 1 1 0 1 1 1 1 Major intrinsic protein SPW PF03779.14 OAP60801.1 - 0.026 14.1 3.5 0.053 13.1 1.1 2.5 2 0 0 2 2 2 0 SPW repeat MFS_1 PF07690.16 OAP60802.1 - 6.7e-27 94.3 32.4 6.7e-27 94.3 32.4 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily AMP-binding PF00501.28 OAP60803.1 - 1.4e-75 254.6 0.0 1.6e-75 254.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAP60803.1 - 8.1e-15 55.6 0.1 1.6e-14 54.6 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Fungal_trans PF04082.18 OAP60804.1 - 9.3e-23 80.6 3.0 1.4e-22 80.0 3.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain ECH_1 PF00378.20 OAP60805.1 - 4e-23 82.0 0.0 1.4e-22 80.3 0.0 1.8 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAP60805.1 - 3.5e-20 72.8 0.0 4e-20 72.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Glycos_transf_3 PF00591.21 OAP60806.1 - 3.5e-61 207.0 0.0 3.6e-49 167.6 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 OAP60806.1 - 2e-07 30.8 0.0 6.8e-07 29.0 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase family, helical bundle domain DNA_RNApol_7kD PF03604.13 OAP60807.1 - 9.7e-16 57.2 4.5 1.2e-15 56.8 4.5 1.1 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit DZR PF12773.7 OAP60807.1 - 0.0092 16.0 0.2 0.014 15.4 0.2 1.3 1 0 0 1 1 1 1 Double zinc ribbon zf_UBZ PF18439.1 OAP60807.1 - 0.012 15.2 0.5 0.88 9.2 0.1 2.1 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger UPF0547 PF10571.9 OAP60807.1 - 0.024 14.7 0.8 0.062 13.4 0.8 1.6 1 1 0 1 1 1 0 Uncharacterised protein family UPF0547 zinc-ribbon_6 PF10005.9 OAP60807.1 - 0.03 15.0 0.3 0.039 14.6 0.3 1.2 1 0 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_10 PF10058.9 OAP60807.1 - 0.042 13.6 0.3 0.45 10.3 0.0 2.1 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein DUF1451 PF07295.11 OAP60807.1 - 0.065 13.3 0.3 0.076 13.0 0.3 1.1 1 0 0 1 1 1 0 Zinc-ribbon containing domain Zn-ribbon_8 PF09723.10 OAP60807.1 - 0.35 11.0 2.9 3.2 7.9 2.7 2.1 1 1 1 2 2 2 0 Zinc ribbon domain HET PF06985.11 OAP60808.1 - 8.3e-38 130.0 0.4 1.4e-37 129.3 0.4 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Bys1 PF04681.12 OAP60809.1 - 0.0021 18.0 2.5 0.0066 16.4 2.5 1.7 1 1 0 1 1 1 1 Blastomyces yeast-phase-specific protein VIT1 PF01988.19 OAP60810.1 - 1.2e-61 208.4 2.5 1.4e-61 208.1 2.5 1.1 1 0 0 1 1 1 1 VIT family Mod_r PF07200.13 OAP60812.1 - 1.9e-21 76.7 1.7 2.4e-21 76.4 1.7 1.1 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein ALIX_LYPXL_bnd PF13949.6 OAP60812.1 - 0.00026 20.4 1.6 0.00036 19.9 1.6 1.2 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV UPF0242 PF06785.11 OAP60812.1 - 0.0063 16.7 2.1 0.011 15.9 2.1 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus DivIC PF04977.15 OAP60812.1 - 0.19 11.5 2.2 0.61 9.9 0.9 2.2 2 0 0 2 2 2 0 Septum formation initiator APG6_N PF17675.1 OAP60812.1 - 0.37 11.3 5.1 0.083 13.4 1.1 1.8 2 0 0 2 2 2 0 Apg6 coiled-coil region FUSC PF04632.12 OAP60812.1 - 0.62 8.5 6.2 0.8 8.2 6.2 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family TolA_bind_tri PF16331.5 OAP60812.1 - 1.5 8.9 8.6 1.7 8.8 7.0 1.9 1 1 1 2 2 2 0 TolA binding protein trimerisation TPR_MLP1_2 PF07926.12 OAP60812.1 - 2.8 8.0 8.6 0.17 11.9 1.7 2.1 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein CENP-H PF05837.12 OAP60812.1 - 7.7 7.0 8.1 0.8 10.1 3.8 1.6 2 0 0 2 2 2 0 Centromere protein H (CENP-H) CLZ PF16526.5 OAP60812.1 - 9.7 6.6 8.0 0.4 11.1 1.5 2.0 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels SF3A2 PF16835.5 OAP60813.1 - 1.6e-38 130.9 0.0 2.5e-38 130.3 0.0 1.3 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 OAP60813.1 - 1.9e-05 24.9 2.5 2e-05 24.8 0.5 2.0 2 0 0 2 2 2 1 Zinc-finger of C2H2 type PRP4 PF08799.11 OAP60813.1 - 0.05 13.2 1.5 0.11 12.1 1.5 1.6 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like Ank_2 PF12796.7 OAP60815.1 - 1.9e-12 47.6 0.0 9.3e-12 45.4 0.0 1.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OAP60815.1 - 4e-12 45.2 0.1 9.8e-06 25.6 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 OAP60815.1 - 9.8e-11 42.0 0.2 3.6e-07 30.6 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OAP60815.1 - 1.1e-10 41.5 0.6 1.1e-07 31.9 0.0 3.3 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 OAP60815.1 - 1.3e-07 31.8 0.1 2.2e-06 27.9 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat Esterase_phd PF10503.9 OAP60816.1 - 6.3e-13 48.7 1.3 1.4e-11 44.3 0.6 2.4 2 1 0 2 2 2 1 Esterase PHB depolymerase Abhydrolase_2 PF02230.16 OAP60816.1 - 9e-06 25.6 0.0 0.00043 20.1 0.0 2.1 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase FSH1 PF03959.13 OAP60816.1 - 1.7e-05 24.6 0.0 0.00099 18.8 0.0 2.2 1 1 1 2 2 2 1 Serine hydrolase (FSH1) Hydrolase_4 PF12146.8 OAP60816.1 - 0.00024 20.4 0.1 0.6 9.3 0.1 2.3 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OAP60816.1 - 0.00045 20.9 2.5 0.00061 20.5 2.5 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 OAP60816.1 - 0.001 19.0 0.0 0.0014 18.5 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OAP60816.1 - 0.0027 17.2 3.0 0.13 11.7 0.3 3.1 2 1 0 3 3 3 1 Prolyl oligopeptidase family AXE1 PF05448.12 OAP60816.1 - 0.009 14.7 0.2 0.055 12.1 0.1 2.0 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) Esterase PF00756.20 OAP60816.1 - 0.016 14.9 0.1 0.047 13.3 0.1 1.6 1 1 0 1 1 1 0 Putative esterase Lipase_3 PF01764.25 OAP60816.1 - 0.079 12.8 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Lipase (class 3) DLH PF01738.18 OAP60816.1 - 0.19 11.3 0.0 0.31 10.6 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family zf-C2H2_assoc3 PF16637.5 OAP60817.1 - 0.14 12.3 2.1 1.4 9.2 0.4 2.4 1 1 1 2 2 2 0 Putative zinc-finger between two C2H2 zinc-fingers on Patz DUF2263 PF10021.9 OAP60818.1 - 2.8e-20 73.2 0.0 7.9e-20 71.7 0.0 1.7 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Macro PF01661.21 OAP60818.1 - 0.032 14.3 0.0 0.052 13.6 0.0 1.3 1 0 0 1 1 1 0 Macro domain Enkurin PF13864.6 OAP60819.1 - 0.044 14.2 0.1 0.076 13.4 0.1 1.3 1 0 0 1 1 1 0 Calmodulin-binding PAP2_3 PF14378.6 OAP60819.1 - 0.098 12.3 7.6 0.16 11.6 7.6 1.3 1 1 0 1 1 1 0 PAP2 superfamily Tn7_Tnp_TnsA_C PF08721.11 OAP60819.1 - 0.13 12.9 0.1 0.22 12.2 0.1 1.3 1 0 0 1 1 1 0 TnsA endonuclease C terminal Ribosomal_L3 PF00297.22 OAP60820.1 - 1.7e-17 63.5 4.3 5.1e-16 58.6 1.7 2.2 1 1 1 2 2 2 2 Ribosomal protein L3 DUF4267 PF14087.6 OAP60822.1 - 3e-22 78.8 6.0 3.7e-22 78.5 6.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) DUF5337 PF17272.2 OAP60822.1 - 0.02 14.7 0.3 0.065 13.1 0.0 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5337) Sugar_tr PF00083.24 OAP60823.1 - 1.4e-53 182.4 24.7 1.8e-53 182.0 24.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP60823.1 - 1.2e-10 40.9 45.0 7.1e-09 35.1 35.5 2.4 1 1 1 3 3 3 2 Major Facilitator Superfamily Ank_4 PF13637.6 OAP60824.1 - 1.1e-32 112.0 14.3 8.8e-11 42.1 0.0 6.6 4 2 3 7 7 7 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 OAP60824.1 - 8.6e-30 103.2 5.2 4.5e-12 46.4 0.1 3.9 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) SPX PF03105.19 OAP60824.1 - 1e-19 71.8 10.9 5.3e-09 36.5 0.3 3.3 1 1 2 3 3 3 3 SPX domain Ank_3 PF13606.6 OAP60824.1 - 7.7e-18 62.7 6.7 0.0014 19.0 0.0 7.1 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.6 OAP60824.1 - 1.2e-16 60.5 10.4 7.3e-06 26.2 0.1 5.5 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 OAP60824.1 - 3.5e-12 46.2 12.8 0.038 14.4 0.0 8.0 8 0 0 8 8 8 3 Ankyrin repeat GDPD PF03009.17 OAP60824.1 - 8.4e-07 29.0 0.0 2.4e-06 27.5 0.0 1.7 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Mito_carr PF00153.27 OAP60827.1 - 5.4e-67 221.8 6.5 1.2e-24 86.0 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4748 PF15932.5 OAP60827.1 - 0.042 13.6 0.8 0.12 12.1 0.8 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4748) Kri1 PF05178.12 OAP60828.1 - 1.2e-29 102.9 18.1 1.2e-29 102.9 18.1 5.1 6 1 0 6 6 6 1 KRI1-like family Kri1_C PF12936.7 OAP60828.1 - 1.6e-29 101.9 0.4 1.6e-29 101.9 0.4 4.7 4 2 1 5 5 5 1 KRI1-like family C-terminal CRISPR_Cse2 PF09485.10 OAP60828.1 - 0.03 14.9 6.1 0.074 13.6 6.1 1.7 1 0 0 1 1 1 0 CRISPR-associated protein Cse2 (CRISPR_cse2) VASt PF16016.5 OAP60829.1 - 8.2e-36 123.7 0.0 1.5e-35 122.9 0.0 1.5 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain BAR_3 PF16746.5 OAP60829.1 - 8.8e-16 58.3 1.3 3e-15 56.6 1.1 1.9 1 1 1 2 2 2 1 BAR domain of APPL family PH PF00169.29 OAP60829.1 - 1.9e-09 38.0 0.0 1e-08 35.6 0.0 2.3 2 0 0 2 2 2 1 PH domain GRAM PF02893.20 OAP60829.1 - 0.005 16.7 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 GRAM domain Tup_N PF08581.10 OAP60829.1 - 0.54 10.6 2.2 0.67 10.3 0.6 1.9 2 0 0 2 2 2 0 Tup N-terminal Fungal_trans_2 PF11951.8 OAP60830.1 - 3.7e-08 32.6 1.0 5.6e-08 32.0 1.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Solute_trans_a PF03619.16 OAP60831.1 - 2.7e-68 230.4 8.9 3.7e-68 229.9 8.9 1.2 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Acyl-CoA_dh_1 PF00441.24 OAP60832.1 - 2e-33 115.7 4.1 3e-33 115.1 4.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 OAP60832.1 - 1.7e-22 79.4 0.0 2.9e-22 78.7 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 OAP60832.1 - 3.2e-13 50.3 1.9 6.1e-13 49.4 0.2 2.4 2 2 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 OAP60832.1 - 8.1e-08 32.6 2.2 1.3e-07 31.9 2.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain CrtC PF07143.11 OAP60832.1 - 0.12 13.0 0.0 0.21 12.2 0.0 1.3 1 0 0 1 1 1 0 CrtC N-terminal lipocalin domain HpcH_HpaI PF03328.14 OAP60833.1 - 4.2e-31 107.8 0.0 5.9e-31 107.3 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family DUF836 PF05768.14 OAP60834.1 - 3.2e-09 37.1 0.2 5.2e-08 33.2 0.2 2.0 1 1 0 1 1 1 1 Glutaredoxin-like domain (DUF836) MFS_1 PF07690.16 OAP60835.1 - 2.2e-37 128.8 62.0 1.6e-32 112.8 35.8 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.18 OAP60836.1 - 4.2e-05 22.7 0.0 7.5e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain p450 PF00067.22 OAP60837.1 - 1.1e-61 209.0 0.0 1.4e-61 208.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Acetyltransf_1 PF00583.25 OAP60838.1 - 1.2e-10 41.7 0.0 2.1e-10 40.9 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OAP60838.1 - 5.7e-09 36.0 0.0 1e-08 35.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OAP60838.1 - 2.5e-08 34.2 0.0 5.1e-08 33.2 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 OAP60838.1 - 0.00047 20.2 0.0 0.00072 19.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAP60838.1 - 0.0065 16.4 0.0 0.014 15.4 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein OrfB_IS605 PF01385.19 OAP60839.1 - 0.0058 16.8 0.2 2.4 8.4 0.1 2.6 2 0 0 2 2 2 2 Probable transposase FlxA PF14282.6 OAP60839.1 - 0.084 12.9 2.6 0.28 11.2 2.6 1.9 1 0 0 1 1 1 0 FlxA-like protein ACOX PF01756.19 OAP60839.1 - 0.17 11.5 0.3 0.48 10.0 0.0 1.8 2 0 0 2 2 2 0 Acyl-CoA oxidase DUF3138 PF11336.8 OAP60839.1 - 0.18 10.4 0.7 0.73 8.4 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) Leu_zip PF15294.6 OAP60839.1 - 2.2 7.7 6.9 0.32 10.5 1.5 2.2 2 0 0 2 2 2 0 Leucine zipper DivIC PF04977.15 OAP60839.1 - 9.9 6.0 7.4 21 4.9 1.4 2.5 2 0 0 2 2 2 0 Septum formation initiator Anp1 PF03452.14 OAP60841.1 - 3.2e-108 361.1 0.0 3.8e-108 360.9 0.0 1.1 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.26 OAP60841.1 - 0.006 16.4 0.6 0.04 13.7 0.1 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 2 Sugar_tr PF00083.24 OAP60844.1 - 2.2e-127 425.7 28.3 2.5e-127 425.5 28.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP60844.1 - 5.9e-22 78.1 30.0 8.4e-13 48.0 11.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily z-alpha PF02295.17 OAP60844.1 - 0.046 13.8 0.0 0.081 13.0 0.0 1.3 1 0 0 1 1 1 0 Adenosine deaminase z-alpha domain SirB PF04247.12 OAP60844.1 - 0.054 13.6 1.7 6.8 6.8 0.1 2.8 2 0 0 2 2 2 0 Invasion gene expression up-regulator, SirB MFS_1 PF07690.16 OAP60845.1 - 1.6e-13 50.3 32.9 1.6e-13 50.3 32.9 3.8 2 2 1 3 3 3 2 Major Facilitator Superfamily LapA_dom PF06305.11 OAP60845.1 - 0.15 11.9 4.2 1 9.2 0.2 3.5 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain MFS_1 PF07690.16 OAP60846.1 - 0.00023 20.2 6.7 0.00025 20.1 6.7 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Barwin PF00967.17 OAP60847.1 - 0.0046 16.8 1.2 0.0074 16.1 1.2 1.3 1 0 0 1 1 1 1 Barwin family ABC1 PF03109.16 OAP60848.1 - 1.2e-30 106.1 0.0 2e-30 105.4 0.0 1.4 1 0 0 1 1 1 1 ABC1 family Acetyltransf_7 PF13508.7 OAP60848.1 - 9.3e-06 26.0 0.0 2.3e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OAP60848.1 - 0.00022 21.2 0.0 0.0005 20.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain RIO1 PF01163.22 OAP60848.1 - 0.063 12.9 0.0 0.15 11.6 0.0 1.6 1 0 0 1 1 1 0 RIO1 family Mur_ligase_M PF08245.12 OAP60849.1 - 1.6e-08 34.8 0.0 3.7e-08 33.6 0.0 1.6 2 0 0 2 2 2 1 Mur ligase middle domain Acetyltransf_10 PF13673.7 OAP60850.1 - 3.2e-07 30.3 0.0 5.5e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAP60850.1 - 3.5e-06 27.2 0.0 1e-05 25.7 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OAP60850.1 - 1.6e-05 25.2 0.0 3.6e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain EHN PF06441.12 OAP60851.1 - 1.4e-35 121.9 0.2 3.4e-35 120.7 0.2 1.7 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 OAP60851.1 - 2.9e-06 27.1 0.0 6.1e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Fungal_trans_2 PF11951.8 OAP60852.1 - 7.2e-09 34.9 0.0 1.3e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Choline_kinase PF01633.20 OAP60853.1 - 1.1e-43 149.3 0.0 5.4e-42 143.8 0.0 2.1 2 0 0 2 2 2 2 Choline/ethanolamine kinase APH PF01636.23 OAP60853.1 - 2.7e-07 30.8 0.7 3.6e-07 30.4 0.1 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.20 OAP60853.1 - 0.015 14.6 0.0 0.022 14.1 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase CPL PF08144.11 OAP60854.1 - 2.4e-32 112.3 0.3 2.6e-30 105.6 0.0 3.8 3 1 2 5 5 5 1 CPL (NUC119) domain PUF PF00806.19 OAP60854.1 - 0.0023 17.5 0.6 1.8 8.4 0.0 3.8 3 0 0 3 3 3 2 Pumilio-family RNA binding repeat Guanylate_kin PF00625.21 OAP60858.1 - 1.5e-57 194.2 0.0 2.2e-57 193.7 0.0 1.2 1 0 0 1 1 1 1 Guanylate kinase AAA_33 PF13671.6 OAP60858.1 - 1e-06 29.0 0.2 1.5e-05 25.2 0.2 2.2 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 OAP60858.1 - 2.5e-05 24.1 0.2 0.096 12.4 0.1 2.2 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 OAP60858.1 - 3.2e-05 24.4 0.1 9.5e-05 22.8 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 OAP60858.1 - 5.1e-05 23.8 0.1 0.00021 21.8 0.0 2.0 1 1 1 2 2 2 1 AAA domain AAA_28 PF13521.6 OAP60858.1 - 0.00035 20.9 0.0 0.0047 17.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 OAP60858.1 - 0.00041 20.3 0.0 0.00089 19.2 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 OAP60858.1 - 0.00079 19.7 0.0 0.0022 18.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 OAP60858.1 - 0.0012 19.4 0.0 0.0021 18.6 0.0 1.7 1 1 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 OAP60858.1 - 0.003 17.3 0.3 0.017 14.8 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA PF00004.29 OAP60858.1 - 0.0037 17.7 1.0 0.15 12.5 0.1 2.3 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 OAP60858.1 - 0.0088 16.1 0.0 0.018 15.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Rad17 PF03215.15 OAP60858.1 - 0.012 15.5 0.0 0.03 14.2 0.0 1.7 2 0 0 2 2 2 0 Rad17 P-loop domain dNK PF01712.19 OAP60858.1 - 0.029 14.2 0.3 2.9 7.7 0.0 2.4 2 1 0 2 2 2 0 Deoxynucleoside kinase RNA_helicase PF00910.22 OAP60858.1 - 0.031 14.7 0.1 0.12 12.8 0.0 2.0 2 0 0 2 2 2 0 RNA helicase AAA_7 PF12775.7 OAP60858.1 - 0.04 13.4 0.0 0.096 12.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region Thymidylate_kin PF02223.17 OAP60858.1 - 0.042 13.5 0.1 1.8 8.2 0.1 2.2 2 0 0 2 2 2 0 Thymidylate kinase Viral_helicase1 PF01443.18 OAP60858.1 - 0.097 12.4 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 OAP60858.1 - 0.1 12.3 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 OAP60858.1 - 0.1 12.2 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain CPT PF07931.12 OAP60858.1 - 0.14 12.0 0.0 1.8 8.4 0.0 2.1 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Mg_chelatase PF01078.21 OAP60858.1 - 0.17 11.3 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_23 PF13476.6 OAP60858.1 - 0.25 11.8 3.2 0.62 10.5 3.2 1.8 1 1 0 1 1 1 0 AAA domain Septin PF00735.18 OAP60859.1 - 1.2e-112 375.8 0.5 1.4e-112 375.6 0.5 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 OAP60859.1 - 6e-08 32.8 0.0 1.4e-07 31.5 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 OAP60859.1 - 3.6e-06 26.4 0.0 6.8e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 OAP60859.1 - 1.1e-05 25.4 0.5 8.3e-05 22.5 0.1 2.1 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 OAP60859.1 - 1.7e-05 24.4 0.5 0.0041 16.7 0.0 2.3 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 OAP60859.1 - 0.00075 19.6 0.3 0.83 9.7 0.2 2.5 1 1 1 2 2 2 2 Dynamin family NB-ARC PF00931.22 OAP60859.1 - 0.0024 17.1 0.1 0.0044 16.2 0.1 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 OAP60859.1 - 0.0075 16.7 0.0 0.025 15.0 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_7 PF12775.7 OAP60859.1 - 0.0076 15.8 0.0 0.046 13.2 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_22 PF13401.6 OAP60859.1 - 0.0089 16.3 0.0 0.017 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 OAP60859.1 - 0.01 16.4 0.5 0.015 15.8 0.5 1.8 1 1 0 1 1 1 1 ABC transporter Gtr1_RagA PF04670.12 OAP60859.1 - 0.037 13.4 0.0 0.4 10.0 0.0 2.1 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region G-alpha PF00503.20 OAP60859.1 - 0.058 12.5 1.0 0.3 10.2 0.2 2.0 1 1 1 2 2 2 0 G-protein alpha subunit FtsK_SpoIIIE PF01580.18 OAP60859.1 - 0.06 12.7 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family T2SSE PF00437.20 OAP60859.1 - 0.081 12.0 0.0 0.19 10.7 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_23 PF13476.6 OAP60859.1 - 0.11 13.0 0.4 0.19 12.2 0.2 1.6 1 1 0 1 1 1 0 AAA domain Microtub_bd PF16796.5 OAP60859.1 - 0.11 12.4 0.2 0.33 10.9 0.0 1.9 2 1 0 2 2 2 0 Microtubule binding Roc PF08477.13 OAP60859.1 - 0.13 12.4 0.0 0.28 11.4 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 OAP60859.1 - 0.18 11.6 0.0 0.39 10.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain WD40 PF00400.32 OAP60860.1 - 3.8e-24 84.5 10.3 7.8e-09 36.0 0.9 7.0 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAP60860.1 - 1.3e-13 51.0 0.4 0.00013 22.2 0.2 4.9 2 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OAP60860.1 - 9.3e-06 25.6 0.0 0.0094 15.9 0.0 3.1 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 OAP60860.1 - 5e-05 22.0 0.0 0.00043 18.9 0.0 2.0 1 1 0 1 1 1 1 Cytochrome D1 heme domain Lactonase PF10282.9 OAP60860.1 - 0.0024 17.2 0.0 0.0049 16.2 0.0 1.5 2 0 0 2 2 2 1 Lactonase, 7-bladed beta-propeller Ribosomal_L32p PF01783.23 OAP60860.1 - 0.0032 17.7 3.0 0.0063 16.8 3.0 1.5 1 0 0 1 1 1 1 Ribosomal L32p protein family Nup160 PF11715.8 OAP60860.1 - 0.0043 15.8 0.6 0.09 11.4 0.0 2.7 2 1 1 3 3 3 1 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 OAP60860.1 - 0.026 13.5 0.0 1.7 7.5 0.0 2.9 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 OAP60860.1 - 0.03 13.6 0.0 9.7 5.4 0.0 3.2 4 0 0 4 4 4 0 WD40-like domain Nbas_N PF15492.6 OAP60860.1 - 0.04 13.2 0.5 8.9 5.5 0.0 3.3 2 1 2 4 4 4 0 Neuroblastoma-amplified sequence, N terminal Hira PF07569.11 OAP60860.1 - 0.066 12.9 0.3 2.6 7.7 0.0 2.6 2 0 0 2 2 2 0 TUP1-like enhancer of split Sulfate_transp PF00916.20 OAP60861.1 - 0.0041 15.9 0.1 0.0042 15.9 0.1 1.1 1 0 0 1 1 1 1 Sulfate permease family Aim19 PF10315.9 OAP60861.1 - 0.018 15.3 0.1 0.024 14.9 0.1 1.3 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 19 DUF1977 PF09320.11 OAP60862.1 - 5.2e-27 94.2 1.0 8.5e-27 93.5 0.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1977) DnaJ PF00226.31 OAP60862.1 - 4e-22 78.1 1.4 6.9e-22 77.3 0.2 1.9 2 0 0 2 2 2 1 DnaJ domain Ufd2P_core PF10408.9 OAP60863.1 - 1.3e-213 711.2 12.5 1.5e-213 710.9 12.5 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 OAP60863.1 - 1.2e-24 86.3 2.6 2.9e-24 85.0 1.6 2.3 2 0 0 2 2 2 1 U-box domain FAD_SOX PF18371.1 OAP60863.1 - 0.0032 17.8 0.7 4.5 7.7 0.1 2.8 2 0 0 2 2 2 2 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase SIMPL PF04402.14 OAP60863.1 - 0.078 13.4 0.0 0.078 13.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF541) DUF2203 PF09969.9 OAP60863.1 - 0.13 13.0 0.6 2 9.2 0.1 2.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Not3 PF04065.15 OAP60863.1 - 0.55 9.6 4.1 12 5.3 0.3 2.6 2 0 0 2 2 2 0 Not1 N-terminal domain, CCR4-Not complex component CDT1_C PF16679.5 OAP60863.1 - 0.58 10.6 7.2 1.7 9.2 1.2 3.0 2 0 0 2 2 2 0 DNA replication factor Cdt1 C-terminal domain Methyltransf_23 PF13489.6 OAP60864.1 - 3.6e-11 43.2 0.0 6.8e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAP60864.1 - 2.4e-07 30.6 0.0 1.6e-06 28.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAP60864.1 - 2.6e-07 31.2 0.0 1e-06 29.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAP60864.1 - 4.1e-07 30.7 0.0 1.2e-06 29.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAP60864.1 - 6.7e-07 29.9 0.0 0.00012 22.7 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAP60864.1 - 0.22 10.8 0.0 0.8 9.0 0.0 1.7 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family NIPSNAP PF07978.13 OAP60865.1 - 1.5e-27 95.8 0.1 1.7e-27 95.6 0.1 1.0 1 0 0 1 1 1 1 NIPSNAP Peptidase_M19 PF01244.21 OAP60866.1 - 8.6e-99 330.7 0.0 1e-98 330.5 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) DIOX_N PF14226.6 OAP60867.1 - 5.9e-22 78.6 0.0 9.3e-22 78.0 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OAP60867.1 - 4.6e-19 68.8 0.0 1.2e-18 67.5 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily RRM_1 PF00076.22 OAP60870.1 - 2.3e-14 53.0 0.0 5.6e-14 51.7 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 OAP60870.1 - 0.031 14.3 0.1 0.076 13.0 0.1 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RL PF17797.1 OAP60870.1 - 0.067 13.1 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 RL domain Hydrolase_6 PF13344.6 OAP60870.1 - 0.13 12.4 0.2 0.5 10.5 0.0 2.1 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase TEX15 PF15326.6 OAP60870.1 - 4.4 7.0 6.1 12 5.5 6.1 1.7 1 0 0 1 1 1 0 Testis expressed sequence 15 RTC PF01137.21 OAP60871.1 - 1e-46 158.9 0.0 1e-36 126.2 0.0 2.1 2 0 0 2 2 2 2 RNA 3'-terminal phosphate cyclase Ricin_B_lectin PF00652.22 OAP60872.1 - 2.5e-17 63.3 0.0 4e-05 23.9 0.0 4.2 2 2 3 5 5 5 5 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 OAP60872.1 - 6e-09 36.5 0.0 0.012 16.3 0.0 4.5 4 0 0 4 4 4 2 Ricin-type beta-trefoil lectin domain-like FIST_C PF10442.9 OAP60872.1 - 0.012 15.5 0.0 5.6 7.0 0.0 2.4 2 0 0 2 2 2 0 FIST C domain CDtoxinA PF03498.14 OAP60872.1 - 0.013 15.1 3.2 2.7 7.6 0.0 3.9 2 2 2 4 4 4 0 Cytolethal distending toxin A/C domain FAD_binding_3 PF01494.19 OAP60873.1 - 1.4e-17 63.9 1.8 4.1e-11 42.7 0.1 2.1 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 OAP60873.1 - 2.4e-09 36.9 0.5 1.3e-06 27.9 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAP60873.1 - 4.3e-07 30.4 0.1 1.1e-06 29.1 0.1 1.6 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAP60873.1 - 2.9e-05 23.8 1.6 0.00014 21.6 0.6 2.1 1 1 1 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAP60873.1 - 0.00021 21.5 0.2 0.00052 20.2 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 OAP60873.1 - 0.0027 17.0 0.2 0.0027 17.0 0.2 1.5 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 OAP60873.1 - 0.0074 15.4 0.0 0.014 14.5 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein GIDA PF01134.22 OAP60873.1 - 0.048 12.7 0.5 0.065 12.3 0.5 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_Gly3P_dh_N PF01210.23 OAP60873.1 - 0.066 13.2 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.16 OAP60873.1 - 0.095 12.3 0.1 0.19 11.4 0.1 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Trp_halogenase PF04820.14 OAP60873.1 - 0.59 8.9 2.7 0.82 8.4 0.5 1.9 1 1 0 2 2 2 0 Tryptophan halogenase Peptidase_M49 PF03571.15 OAP60874.1 - 1.2e-242 806.2 0.0 1.5e-242 805.9 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M49 cIII PF08134.11 OAP60874.1 - 0.21 11.4 1.8 0.62 9.9 0.4 2.4 2 0 0 2 2 2 0 cIII protein family ADH_zinc_N PF00107.26 OAP60875.1 - 2.2e-09 37.4 0.1 4.8e-09 36.3 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAP60875.1 - 1.5e-07 31.2 0.1 3.1e-07 30.2 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 OAP60875.1 - 5.4e-06 27.5 0.0 1.1e-05 26.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Zn_clus PF00172.18 OAP60876.1 - 2.7e-09 37.0 9.0 4.3e-09 36.3 9.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 OAP60876.1 - 8.1e-07 28.2 0.5 0.012 14.5 0.2 2.4 2 1 0 2 2 2 2 Fungal specific transcription factor domain E1-E2_ATPase PF00122.20 OAP60877.1 - 8.1e-45 152.6 1.7 8.1e-45 152.6 1.7 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 OAP60877.1 - 3.8e-21 76.4 0.2 1e-20 74.9 0.0 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 OAP60877.1 - 3.6e-13 49.7 1.0 8.8e-13 48.5 0.2 2.2 2 0 0 2 2 2 1 Heavy-metal-associated domain dsrm PF00035.26 OAP60878.1 - 0.00047 20.8 0.0 0.0014 19.3 0.0 1.8 1 0 0 1 1 1 1 Double-stranded RNA binding motif OTT_1508_deam PF14441.6 OAP60879.1 - 1.5e-19 69.8 0.4 3.6e-19 68.5 0.4 1.7 1 0 0 1 1 1 1 OTT_1508-like deaminase DUF4487 PF14868.6 OAP60879.1 - 0.015 14.2 0.1 0.03 13.2 0.0 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4487) DUF5056 PF16479.5 OAP60881.1 - 0.12 12.6 0.7 0.54 10.5 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5056) Abhydrolase_6 PF12697.7 OAP60882.1 - 1.6e-11 45.3 1.1 2.2e-11 44.8 1.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAP60882.1 - 7.4e-07 28.7 0.0 1.1e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OAP60882.1 - 0.0028 17.4 0.0 0.005 16.5 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold PTCB-BRCT PF12738.7 OAP60883.1 - 3.3e-36 123.0 2.0 1.2e-20 73.2 0.3 5.3 5 0 0 5 5 5 4 twin BRCT domain RTT107_BRCT_5 PF16770.5 OAP60883.1 - 2.4e-30 104.3 0.2 1.7e-26 92.0 0.0 4.3 4 0 0 4 4 4 2 Regulator of Ty1 transposition protein 107 BRCT domain BRCT PF00533.26 OAP60883.1 - 4.8e-30 103.8 0.0 5e-10 39.6 0.0 6.0 6 0 0 6 6 6 4 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 OAP60883.1 - 9.3e-29 99.7 0.0 0.0003 21.1 0.1 6.4 6 0 0 6 6 6 5 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 OAP60883.1 - 3.8e-11 43.1 0.0 0.001 19.3 0.0 4.5 4 0 0 4 4 4 3 DNA ligase 3 BRCT domain ESCRT-II PF05871.12 OAP60884.1 - 9.8e-53 178.2 0.9 1.3e-52 177.7 0.3 1.5 2 0 0 2 2 2 1 ESCRT-II complex subunit PHD PF00628.29 OAP60885.1 - 6.3e-09 35.6 9.4 1.3e-08 34.6 9.4 1.6 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 OAP60885.1 - 0.0036 16.8 5.7 0.0088 15.6 5.7 1.6 1 0 0 1 1 1 1 PHD-finger DDT PF02791.17 OAP60885.1 - 0.25 11.7 1.0 0.39 11.1 0.2 1.7 2 0 0 2 2 2 0 DDT domain C1_2 PF03107.16 OAP60885.1 - 0.43 10.9 8.9 0.074 13.4 3.9 2.1 2 0 0 2 2 2 0 C1 domain 2-Hacid_dh_C PF02826.19 OAP60886.1 - 3.9e-34 117.6 0.0 5.6e-34 117.0 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 OAP60886.1 - 4e-14 52.4 0.0 4.8e-14 52.2 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NmrA PF05368.13 OAP60887.1 - 3.9e-27 95.3 0.0 4.6e-27 95.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAP60887.1 - 8.6e-11 42.1 0.0 1.7e-10 41.1 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAP60887.1 - 7.4e-06 25.6 0.1 0.00038 20.0 0.1 2.3 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 OAP60887.1 - 0.0061 17.0 0.1 0.048 14.1 0.0 2.1 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 OAP60887.1 - 0.0066 16.7 0.0 0.013 15.8 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain KR PF08659.10 OAP60887.1 - 0.031 14.2 0.1 0.057 13.3 0.1 1.4 1 0 0 1 1 1 0 KR domain GDP_Man_Dehyd PF16363.5 OAP60887.1 - 0.04 13.3 0.1 1.2 8.5 0.0 2.1 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 OAP60887.1 - 0.056 12.4 0.1 0.083 11.9 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family S1-P1_nuclease PF02265.16 OAP60888.1 - 4.6e-70 236.3 0.7 5.2e-70 236.1 0.7 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease Aconitase PF00330.20 OAP60889.1 - 3.9e-149 497.6 0.0 4.9e-149 497.3 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 OAP60889.1 - 5e-38 130.4 0.0 8e-38 129.7 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain MACPF PF01823.19 OAP60890.1 - 2.6e-16 60.4 0.2 4.1e-16 59.7 0.2 1.2 1 0 0 1 1 1 1 MAC/Perforin domain Fungal_trans PF04082.18 OAP60891.1 - 2.7e-12 46.3 0.2 4.1e-12 45.7 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP60891.1 - 0.00014 21.9 7.0 0.00031 20.8 7.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2408 PF10303.9 OAP60892.1 - 6.3e-48 162.8 5.2 8e-31 107.4 1.3 5.0 2 2 2 4 4 4 4 Protein of unknown function (DUF2408) Baculo_PEP_C PF04513.12 OAP60892.1 - 0.0004 20.5 1.3 0.0044 17.1 0.0 3.1 3 1 1 4 4 4 1 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_lid_8 PF17868.1 OAP60892.1 - 0.017 15.0 0.4 0.19 11.6 0.0 3.0 3 0 0 3 3 3 0 AAA lid domain Spc7 PF08317.11 OAP60892.1 - 0.018 13.9 3.0 0.02 13.8 0.8 1.9 1 1 1 2 2 2 0 Spc7 kinetochore protein TBCA PF02970.16 OAP60892.1 - 0.022 15.1 0.5 0.14 12.5 0.0 2.5 2 1 0 2 2 2 0 Tubulin binding cofactor A HisKA_3 PF07730.13 OAP60892.1 - 0.034 14.7 1.0 0.42 11.2 0.2 2.9 3 0 0 3 3 3 0 Histidine kinase DUF1664 PF07889.12 OAP60892.1 - 0.044 13.8 1.4 0.27 11.3 0.0 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) Rx_N PF18052.1 OAP60892.1 - 0.049 13.9 3.7 7 7.0 0.1 3.2 3 0 0 3 3 3 0 Rx N-terminal domain DUF885 PF05960.11 OAP60892.1 - 0.075 12.7 0.1 0.096 12.3 0.1 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) DUF4201 PF13870.6 OAP60892.1 - 0.12 12.1 7.9 1.6 8.5 1.7 3.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4201) EzrA PF06160.12 OAP60892.1 - 0.15 10.2 4.1 0.16 10.1 0.2 2.4 2 1 0 2 2 2 0 Septation ring formation regulator, EzrA XhlA PF10779.9 OAP60892.1 - 0.71 10.1 5.4 2.7 8.2 0.3 3.4 3 0 0 3 3 3 0 Haemolysin XhlA THOC7 PF05615.13 OAP60892.1 - 1.4 9.2 6.2 20 5.5 0.1 2.4 2 0 0 2 2 2 0 Tho complex subunit 7 NPV_P10 PF05531.12 OAP60892.1 - 1.9 9.0 6.1 4.9 7.7 0.0 3.9 4 1 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Wbp11 PF09429.10 OAP60892.1 - 3.4 8.1 5.6 8 6.9 0.2 3.1 3 0 0 3 3 3 0 WW domain binding protein 11 Exonuc_VII_L PF02601.15 OAP60892.1 - 4.1 6.9 5.4 26 4.3 5.4 2.0 1 1 0 1 1 1 0 Exonuclease VII, large subunit Glyco_hydro_88 PF07470.13 OAP60893.1 - 3.3e-12 46.1 0.0 5e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Amidohydro_3 PF07969.11 OAP60894.1 - 4.4e-48 164.9 1.9 5.1e-48 164.7 1.9 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 OAP60894.1 - 6.8e-10 38.8 4.1 5.2e-08 32.6 1.1 3.0 2 1 0 2 2 2 2 Amidohydrolase family HATPase_c PF02518.26 OAP60895.1 - 1.2e-24 87.0 0.0 2.3e-24 86.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 OAP60895.1 - 7.1e-19 68.0 0.2 4.5e-18 65.4 0.2 2.3 1 1 0 1 1 1 1 Response regulator receiver domain PAS_4 PF08448.10 OAP60895.1 - 1.4e-13 51.1 0.0 1.8e-06 28.2 0.0 3.0 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 OAP60895.1 - 4.5e-12 46.2 0.0 4.5e-08 33.3 0.0 2.9 2 0 0 2 2 2 2 PAS domain HisKA PF00512.25 OAP60895.1 - 1.3e-09 37.9 1.7 1.6e-09 37.6 0.1 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain GAF PF01590.26 OAP60895.1 - 1.8e-06 28.6 0.0 8.3e-06 26.5 0.0 2.1 2 0 0 2 2 2 1 GAF domain PAS_3 PF08447.12 OAP60895.1 - 1.4e-05 25.3 0.3 0.00022 21.4 0.3 2.6 1 1 0 1 1 1 1 PAS fold GAF_2 PF13185.6 OAP60895.1 - 4.7e-05 23.7 0.0 0.0003 21.1 0.0 2.3 2 0 0 2 2 2 1 GAF domain PAS_8 PF13188.7 OAP60895.1 - 0.0001 22.2 0.0 0.00037 20.4 0.0 1.9 1 0 0 1 1 1 1 PAS domain GAF_3 PF13492.6 OAP60895.1 - 0.0012 19.2 0.0 0.0026 18.1 0.0 1.5 1 0 0 1 1 1 1 GAF domain PAS PF00989.25 OAP60895.1 - 0.0013 18.7 0.0 0.0035 17.3 0.0 1.8 1 0 0 1 1 1 1 PAS fold Zn_clus PF00172.18 OAP60896.1 - 1.7e-07 31.2 4.5 3.6e-07 30.2 4.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PrsW-protease PF13367.6 OAP60897.1 - 3.2e-17 62.6 7.5 1.2e-16 60.8 7.5 2.0 1 1 0 1 1 1 1 PrsW family intramembrane metalloprotease TctB PF07331.11 OAP60897.1 - 0.0076 16.5 5.1 0.11 12.7 0.2 3.1 1 1 2 3 3 3 2 Tripartite tricarboxylate transporter TctB family Rtt106 PF08512.12 OAP60898.1 - 6.1e-29 100.3 0.0 9.7e-29 99.6 0.0 1.3 1 0 0 1 1 1 1 Histone chaperone Rttp106-like PH_18 PF18469.1 OAP60898.1 - 1.3e-07 31.7 0.0 2.4e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain G-patch PF01585.23 OAP60899.1 - 5.8e-11 42.1 0.9 1.3e-10 41.0 0.9 1.6 1 0 0 1 1 1 1 G-patch domain RRM_1 PF00076.22 OAP60899.1 - 8.2e-05 22.4 0.0 0.00015 21.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AMP-binding PF00501.28 OAP60900.1 - 4.1e-93 312.3 0.0 4.7e-93 312.1 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAP60900.1 - 2.6e-05 25.1 1.8 9.5e-05 23.3 0.3 2.6 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain GH3 PF03321.13 OAP60900.1 - 0.00031 19.7 0.0 0.001 18.0 0.0 1.7 2 0 0 2 2 2 1 GH3 auxin-responsive promoter YCII PF03795.14 OAP60901.1 - 9.2e-13 48.4 0.0 1.1e-12 48.2 0.0 1.0 1 0 0 1 1 1 1 YCII-related domain Sod_Cu PF00080.20 OAP60902.1 - 8.1e-12 45.5 0.9 1.2e-11 45.0 0.9 1.3 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Sld5 PF05916.11 OAP60903.1 - 1.8e-12 47.7 0.0 2.6e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein zf-RING_2 PF13639.6 OAP60904.1 - 9.6e-05 22.6 12.1 9.6e-05 22.6 12.1 2.3 2 1 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 OAP60904.1 - 0.00034 20.8 8.9 0.00034 20.8 8.9 2.0 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 OAP60904.1 - 0.0033 17.4 4.2 0.0081 16.2 4.2 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 OAP60904.1 - 0.0069 16.5 10.0 0.017 15.3 5.3 2.4 1 1 0 2 2 2 1 FANCL C-terminal domain zf-Di19 PF05605.12 OAP60904.1 - 0.014 15.7 4.2 0.33 11.3 0.0 2.7 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding HMG_box PF00505.19 OAP60905.1 - 1.2e-09 38.5 0.6 2e-09 37.7 0.6 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box SURF4 PF02077.15 OAP60908.1 - 1.1e-94 317.0 9.2 1.2e-94 316.8 9.2 1.0 1 0 0 1 1 1 1 SURF4 family HR_lesion PF05514.11 OAP60908.1 - 1.2 9.3 8.0 1.9 8.7 2.0 2.9 3 1 0 3 3 3 0 HR-like lesion-inducing IU_nuc_hydro PF01156.19 OAP60909.1 - 2e-58 198.4 0.0 4.4e-58 197.2 0.0 1.4 1 1 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase C_LFY_FLO PF17538.2 OAP60909.1 - 0.041 13.4 0.0 0.12 11.8 0.0 1.7 2 0 0 2 2 2 0 DNA Binding Domain (C-terminal) Leafy/Floricaula GST_C PF00043.25 OAP60910.1 - 4.3e-08 33.3 0.0 6.6e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OAP60910.1 - 2.2e-06 27.6 4.7 5.1e-06 26.4 3.1 2.6 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OAP60910.1 - 1.4e-05 25.2 0.0 3.2e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 OAP60910.1 - 3.7e-05 24.0 0.0 6.1e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 OAP60910.1 - 0.0011 19.2 0.0 0.0028 18.0 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OAP60910.1 - 0.0043 17.3 0.0 0.0082 16.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Ribonuc_L-PSP PF01042.21 OAP60911.1 - 3.7e-13 49.5 0.0 4.2e-13 49.4 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP HgmA PF04209.13 OAP60913.1 - 2.5e-132 441.6 0.0 3.1e-132 441.3 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase DUF3425 PF11905.8 OAP60914.1 - 7.2e-13 48.6 0.4 1.4e-12 47.6 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) CDRT4 PF15213.6 OAP60914.1 - 0.029 15.0 1.4 2.6 8.7 0.3 2.4 2 0 0 2 2 2 0 CMT1A duplicated region transcript 4 protein bZIP_1 PF00170.21 OAP60914.1 - 0.12 12.5 7.8 0.23 11.6 7.8 1.4 1 0 0 1 1 1 0 bZIP transcription factor Omptin PF01278.20 OAP60914.1 - 0.14 11.2 0.5 0.21 10.6 0.5 1.2 1 0 0 1 1 1 0 Omptin family PBP1_TM PF14812.6 OAP60914.1 - 0.38 11.2 6.7 0.86 10.0 6.7 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SnoaL_2 PF12680.7 OAP60915.1 - 2e-08 34.8 0.9 3.2e-08 34.1 0.9 1.3 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 OAP60915.1 - 5.2e-06 26.8 0.2 8e-06 26.2 0.2 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_3 PF13474.6 OAP60915.1 - 1.5e-05 25.2 0.1 2.7e-05 24.4 0.1 1.4 1 0 0 1 1 1 1 SnoaL-like domain Lumazine_bd_2 PF12893.7 OAP60915.1 - 0.00033 21.3 0.0 0.0024 18.5 0.0 2.0 2 0 0 2 2 2 1 Putative lumazine-binding SnoaL_4 PF13577.6 OAP60915.1 - 0.00075 19.6 0.7 0.0011 19.1 0.7 1.2 1 0 0 1 1 1 1 SnoaL-like domain LEH PF07858.12 OAP60915.1 - 0.081 13.0 0.2 0.095 12.8 0.2 1.3 1 1 0 1 1 1 0 Limonene-1,2-epoxide hydrolase catalytic domain Ral PF11058.8 OAP60915.1 - 0.17 11.5 0.0 0.92 9.1 0.0 2.0 2 0 0 2 2 2 0 Antirestriction protein Ral DUF4878 PF12870.7 OAP60915.1 - 0.19 12.0 0.0 0.33 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4878) Aa_trans PF01490.18 OAP60916.1 - 7.8e-20 70.9 33.6 1.6e-19 69.9 33.6 1.4 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.6 OAP60916.1 - 0.034 13.0 42.4 0.39 9.5 42.3 2.1 1 1 0 1 1 1 0 Amino acid permease SLATT_fungal PF18142.1 OAP60916.1 - 1.9 8.5 4.4 16 5.5 0.5 2.7 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain NACHT PF05729.12 OAP60917.1 - 9.5e-08 32.1 0.0 7e-07 29.3 0.0 2.5 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 OAP60917.1 - 8.4e-05 23.0 1.8 0.00045 20.7 0.0 3.0 2 1 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 OAP60917.1 - 0.003 17.2 0.0 0.0066 16.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain NB-ARC PF00931.22 OAP60917.1 - 0.0078 15.4 0.0 0.027 13.6 0.0 1.9 1 0 0 1 1 1 1 NB-ARC domain RsgA_GTPase PF03193.16 OAP60917.1 - 0.0085 16.0 0.5 0.19 11.6 0.0 2.8 3 0 0 3 3 3 1 RsgA GTPase AAA_22 PF13401.6 OAP60917.1 - 0.027 14.8 1.3 0.17 12.2 0.0 3.0 2 2 0 2 2 2 0 AAA domain ABC_tran PF00005.27 OAP60917.1 - 0.12 12.9 0.0 0.12 12.9 0.0 2.7 2 1 0 2 2 1 0 ABC transporter dNK PF01712.19 OAP60917.1 - 0.13 12.1 0.5 0.92 9.3 0.0 2.6 3 1 0 3 3 3 0 Deoxynucleoside kinase AAA_18 PF13238.6 OAP60917.1 - 0.14 12.7 0.1 1.1 9.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 OAP60917.1 - 0.17 12.3 0.0 0.63 10.5 0.0 2.0 1 0 0 1 1 1 0 RNA helicase AAA_5 PF07728.14 OAP60917.1 - 0.19 11.7 1.2 33 4.5 0.0 2.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF87 PF01935.17 OAP60917.1 - 0.39 10.8 0.0 0.39 10.8 0.0 2.9 2 1 0 2 2 1 0 Helicase HerA, central domain CBP_BcsQ PF06564.12 OAP60917.1 - 0.48 9.9 5.2 2.4 7.6 3.2 2.6 1 1 1 2 2 2 0 Cellulose biosynthesis protein BcsQ AAA_33 PF13671.6 OAP60917.1 - 3.9 7.6 0.0 3.9 7.6 0.0 3.7 4 1 0 4 4 2 0 AAA domain COesterase PF00135.28 OAP60918.1 - 6.7e-45 153.9 0.0 3.9e-44 151.4 0.0 1.8 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAP60918.1 - 0.16 11.8 0.2 0.61 9.9 0.0 1.9 2 0 0 2 2 2 0 alpha/beta hydrolase fold Arginase PF00491.21 OAP60919.1 - 7.3e-74 248.8 0.1 9e-74 248.5 0.1 1.0 1 0 0 1 1 1 1 Arginase family MatE PF01554.18 OAP60920.1 - 3.6e-44 150.3 26.6 8.3e-26 90.6 5.1 2.4 2 0 0 2 2 2 2 MatE Fungal_trans_2 PF11951.8 OAP60921.1 - 7.1e-39 133.7 0.9 9.1e-39 133.4 0.9 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aminotran_5 PF00266.19 OAP60922.1 - 3.1e-31 108.6 0.0 4.4e-31 108.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V MFS_1 PF07690.16 OAP60923.1 - 7e-50 169.9 31.4 3.9e-49 167.5 27.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAP60923.1 - 8.6e-14 51.2 5.7 8.6e-14 51.2 5.7 2.8 3 1 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 OAP60923.1 - 7.6e-09 34.5 1.0 1.2e-08 33.9 1.0 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Aminotran_1_2 PF00155.21 OAP60924.1 - 9.1e-38 130.4 0.0 1.1e-37 130.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 OAP60924.1 - 0.00057 18.5 0.0 0.00096 17.8 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 OAP60924.1 - 0.041 13.2 0.0 0.071 12.4 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family YafQ_toxin PF15738.5 OAP60924.1 - 0.085 13.2 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial toxin of type II toxin-antitoxin system, YafQ MFS_1 PF07690.16 OAP60925.1 - 2.1e-15 56.5 17.8 3.2e-15 55.9 17.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily CBM_2 PF00553.19 OAP60925.1 - 0.026 14.8 1.0 0.051 13.9 1.0 1.4 1 0 0 1 1 1 0 Cellulose binding domain Ferric_reduct PF01794.19 OAP60926.1 - 3.6e-20 72.4 18.0 3.6e-20 72.4 18.0 2.2 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 OAP60926.1 - 8.1e-18 65.0 0.0 1.2e-17 64.4 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 OAP60926.1 - 6e-10 39.2 0.0 0.00022 21.3 0.0 2.4 2 0 0 2 2 2 2 FAD-binding domain Fasciclin PF02469.22 OAP60927.1 - 1.2e-31 109.6 0.0 1.6e-20 73.7 0.0 2.3 2 0 0 2 2 2 2 Fasciclin domain FTA2 PF13095.6 OAP60928.1 - 4.3e-74 248.7 0.0 6.5e-74 248.2 0.0 1.2 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Fungal_trans PF04082.18 OAP60930.1 - 8e-08 31.6 0.0 1.8e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Serglycin PF04360.12 OAP60930.1 - 0.073 13.0 0.7 0.21 11.6 0.7 1.7 1 0 0 1 1 1 0 Serglycin SBE2 PF17076.5 OAP60931.1 - 0.53 8.5 3.9 0.61 8.2 3.9 1.1 1 0 0 1 1 1 0 SBE2, cell-wall formation DUF3123 PF11321.8 OAP60932.1 - 1.4 9.6 7.5 1 10.0 0.6 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3123) PCI PF01399.27 OAP60933.1 - 8.3e-21 74.5 0.0 2.6e-20 72.9 0.0 1.9 1 0 0 1 1 1 1 PCI domain RPN5_C PF18098.1 OAP60933.1 - 1.6e-12 47.3 0.2 1.6e-12 47.3 0.2 2.0 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN5 C-terminal domain ATP-sulfurylase PF01747.17 OAP60934.1 - 2.1e-85 285.5 0.1 3.1e-85 285.0 0.1 1.3 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.20 OAP60934.1 - 6e-55 185.5 0.0 9.3e-55 184.8 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.6 OAP60934.1 - 2.8e-53 179.8 0.0 4.3e-53 179.2 0.0 1.3 1 0 0 1 1 1 1 PUA-like domain CPT PF07931.12 OAP60934.1 - 0.15 11.9 0.0 0.59 10.0 0.0 2.0 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein PAPS_reduct PF01507.19 OAP60935.1 - 7.9e-46 156.3 0.1 1.4e-45 155.5 0.0 1.4 2 0 0 2 2 2 1 Phosphoadenosine phosphosulfate reductase family HAD PF12710.7 OAP60936.1 - 6.5e-22 78.9 0.0 8.9e-22 78.4 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OAP60936.1 - 1.9e-17 64.3 0.0 2.5e-17 63.9 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 OAP60936.1 - 3.2e-10 40.2 0.1 1e-09 38.6 0.0 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 OAP60936.1 - 0.0049 17.0 0.0 5.1 7.1 0.0 2.9 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 OAP60936.1 - 0.015 14.7 0.0 0.061 12.7 0.0 1.8 1 1 0 1 1 1 0 Putative Phosphatase DUF705 PF05152.12 OAP60936.1 - 0.028 13.9 0.0 0.041 13.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF705) DUF4287 PF14117.6 OAP60936.1 - 0.13 12.4 0.1 0.3 11.3 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4287) DUF4392 PF14336.6 OAP60936.1 - 0.14 11.6 0.1 0.54 9.7 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4392) TrbI_Ftype PF09677.10 OAP60937.1 - 0.13 12.6 0.2 0.13 12.6 0.2 1.9 2 0 0 2 2 2 0 Type-F conjugative transfer system protein (TrbI_Ftype) Strabismus PF06638.11 OAP60937.1 - 0.19 10.3 0.0 0.3 9.7 0.0 1.2 1 0 0 1 1 1 0 Strabismus protein EGF_2 PF07974.13 OAP60937.1 - 0.41 11.1 11.6 0.74 10.2 11.6 1.4 1 0 0 1 1 1 0 EGF-like domain hEGF PF12661.7 OAP60937.1 - 0.43 11.3 6.3 1.1 10.0 6.3 1.7 1 0 0 1 1 1 0 Human growth factor-like EGF EGF PF00008.27 OAP60937.1 - 0.49 10.7 5.3 1.4 9.3 5.3 1.8 1 1 0 1 1 1 0 EGF-like domain Adeno_52K PF03052.15 OAP60938.1 - 0.029 13.8 0.2 0.89 9.0 0.0 2.2 2 0 0 2 2 2 0 Adenoviral protein L1 52/55-kDa ATP-synt_D PF01813.17 OAP60939.1 - 0.00094 19.1 0.0 0.016 15.0 0.0 2.1 2 0 0 2 2 2 2 ATP synthase subunit D Complex1_LYR PF05347.15 OAP60940.1 - 8.4e-23 80.2 2.7 1.2e-22 79.7 2.7 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 OAP60940.1 - 5e-09 36.8 1.3 5.8e-09 36.6 1.3 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Requiem_N PF14051.6 OAP60940.1 - 0.011 16.0 1.2 0.015 15.5 1.2 1.3 1 0 0 1 1 1 0 N-terminal domain of DPF2/REQ. Ribonuclease_P PF00825.18 OAP60940.1 - 0.09 12.9 1.5 1.2 9.3 0.3 2.1 1 1 1 2 2 2 0 Ribonuclease P zf-C2H2_4 PF13894.6 OAP60941.1 - 0.1 13.5 3.0 0.17 12.8 3.0 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger DUF1761 PF08570.10 OAP60942.1 - 4.7e-26 91.5 3.7 5.3e-26 91.3 3.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1761) Methyltransf_16 PF10294.9 OAP60943.1 - 3e-45 154.1 0.0 4.6e-45 153.5 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Met_10 PF02475.16 OAP60943.1 - 0.027 14.2 0.0 0.042 13.6 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein MTS PF05175.14 OAP60943.1 - 0.068 12.7 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain GrpE PF01025.19 OAP60944.1 - 0.02 14.6 5.6 2.1 8.0 3.0 2.2 2 0 0 2 2 2 0 GrpE DUF2563 PF10817.8 OAP60944.1 - 0.07 13.7 0.9 0.17 12.5 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2563) DUF4726 PF15855.5 OAP60944.1 - 0.14 12.4 0.3 0.33 11.2 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4726) FadA PF09403.10 OAP60944.1 - 0.27 11.7 4.7 0.12 12.9 1.5 2.0 2 1 0 2 2 2 0 Adhesion protein FadA DUF1043 PF06295.12 OAP60944.1 - 1 9.3 7.1 0.34 10.9 2.9 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1043) Nucleocapsid-N PF11030.8 OAP60944.1 - 1.4 8.8 3.6 1.5 8.8 0.1 2.2 2 1 0 2 2 2 0 Nucleocapsid protein N ING PF12998.7 OAP60944.1 - 3.6 8.2 7.0 1.5 9.5 1.0 2.4 2 1 1 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding Aminotran_4 PF01063.19 OAP60945.1 - 9.8e-24 84.5 0.0 3.3e-23 82.7 0.0 1.8 1 1 0 1 1 1 1 Amino-transferase class IV Glutaredoxin PF00462.24 OAP60946.1 - 5.8e-15 55.3 0.0 3.1e-14 52.9 0.0 2.2 3 0 0 3 3 3 1 Glutaredoxin Flavoprotein PF02441.19 OAP60947.1 - 9e-41 139.2 0.0 1e-40 139.1 0.0 1.0 1 0 0 1 1 1 1 Flavoprotein UbiA PF01040.18 OAP60948.1 - 8.8e-43 146.4 13.8 1e-42 146.2 13.8 1.0 1 0 0 1 1 1 1 UbiA prenyltransferase family JmjC PF02373.22 OAP60949.1 - 1.2e-09 38.6 0.5 2.1e-08 34.6 0.5 2.6 1 1 0 1 1 1 1 JmjC domain, hydroxylase zf-4CXXC_R1 PF10497.9 OAP60949.1 - 3.5e-07 30.4 6.7 3.5e-07 30.4 6.7 2.6 2 0 0 2 2 2 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Cupin_2 PF07883.11 OAP60949.1 - 0.001 18.8 0.2 0.0048 16.6 0.0 2.2 2 0 0 2 2 2 1 Cupin domain DUF1279 PF06916.13 OAP60950.1 - 2.4e-26 92.1 0.0 3.6e-26 91.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) Coa1 PF08695.10 OAP60951.1 - 8.5e-38 128.7 0.1 1.3e-37 128.2 0.1 1.2 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 Ribosomal_L2_C PF03947.18 OAP60953.1 - 3.7e-46 156.4 1.3 5.8e-45 152.6 1.3 2.4 1 1 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 OAP60953.1 - 5.5e-26 90.3 1.1 1e-25 89.4 1.1 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Fungal_trans PF04082.18 OAP60954.1 - 5.6e-27 94.4 0.2 1e-26 93.5 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain TPR_16 PF13432.6 OAP60955.1 - 3.9e-08 33.8 0.8 0.17 12.5 0.0 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 OAP60955.1 - 4.1e-07 30.2 7.0 0.33 11.3 0.0 5.5 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 OAP60955.1 - 4.4e-05 23.3 1.4 2.8 8.3 0.0 5.8 6 1 0 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 OAP60955.1 - 0.00053 20.4 2.9 4.3 7.9 0.0 4.7 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 OAP60955.1 - 0.0061 16.7 0.0 14 6.2 0.0 4.8 5 1 0 5 5 5 1 Tetratricopeptide repeat Arm_APC_u3 PF16629.5 OAP60955.1 - 0.0064 16.1 0.1 0.011 15.3 0.1 1.3 1 0 0 1 1 1 1 Armadillo-associated region on APC TPR_7 PF13176.6 OAP60955.1 - 0.033 14.2 6.5 9 6.6 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 OAP60955.1 - 0.034 15.0 11.1 14 6.9 0.0 5.4 5 1 1 6 6 6 0 Tetratricopeptide repeat DUF4407 PF14362.6 OAP60955.1 - 1.3 8.3 8.1 0.15 11.4 0.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) NmrA PF05368.13 OAP60956.1 - 3.4e-17 62.8 0.0 4.1e-17 62.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAP60956.1 - 6.6e-07 29.4 0.0 1.2e-06 28.5 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding DUF5624 PF18538.1 OAP60956.1 - 0.00051 20.1 0.0 0.12 12.5 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF5624) Semialdhyde_dh PF01118.24 OAP60956.1 - 0.04 14.3 0.1 0.068 13.6 0.1 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 OAP60956.1 - 0.046 14.0 0.0 0.094 13.0 0.0 1.6 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 OAP60956.1 - 0.073 13.3 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Mito_carr PF00153.27 OAP60957.1 - 1.4e-41 140.3 1.7 1.9e-16 59.7 0.0 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 OAP60957.1 - 0.19 10.8 1.1 0.22 10.7 0.1 1.6 2 0 0 2 2 2 0 Gammaproteobacterial serine protease JAB PF01398.21 OAP60958.1 - 6.6e-09 35.8 0.2 2e-07 31.0 0.2 2.5 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease WLM PF08325.10 OAP60959.1 - 0.053 13.6 0.1 0.053 13.6 0.1 1.6 2 0 0 2 2 2 0 WLM domain Neugrin PF06413.11 OAP60959.1 - 0.056 13.4 1.3 0.06 13.3 1.3 1.1 1 0 0 1 1 1 0 Neugrin INTAP PF16617.5 OAP60959.1 - 0.4 11.1 9.3 0.052 13.9 4.0 2.0 1 1 1 2 2 2 0 Intersectin and clathrin adaptor AP2 binding region zf-C2H2 PF00096.26 OAP60960.1 - 3.9e-07 30.2 16.7 0.0012 19.1 0.8 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAP60960.1 - 0.0013 19.3 16.2 0.0079 16.9 0.4 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.7 OAP60960.1 - 0.0018 18.6 3.3 0.44 11.0 0.1 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-Di19 PF05605.12 OAP60960.1 - 0.0099 16.2 0.2 0.019 15.3 0.2 1.4 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 OAP60960.1 - 0.015 15.6 3.6 1.3 9.4 0.3 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 OAP60960.1 - 0.043 13.8 0.4 0.15 12.1 0.4 2.0 1 0 0 1 1 1 0 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 OAP60960.1 - 0.079 12.6 1.1 0.18 11.5 1.1 1.6 1 0 0 1 1 1 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-H2C2_2 PF13465.6 OAP60960.1 - 0.66 10.5 9.5 5.3 7.6 0.2 4.0 4 0 0 4 4 4 0 Zinc-finger double domain zf-C2H2_11 PF16622.5 OAP60960.1 - 0.95 9.3 5.3 0.4 10.5 0.4 2.3 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-MYST PF17772.1 OAP60960.1 - 7.9 6.2 6.7 1.4 8.5 0.3 2.7 3 0 0 3 3 3 0 MYST family zinc finger domain PNK3P PF08645.11 OAP60962.1 - 4.8e-54 182.4 0.1 7e-54 181.9 0.1 1.3 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.6 OAP60962.1 - 1.8e-11 44.4 0.0 1.4e-10 41.5 0.0 2.4 3 0 0 3 3 3 1 AAA domain Rad17 PF03215.15 OAP60962.1 - 0.009 16.0 0.0 0.051 13.5 0.0 1.9 2 0 0 2 2 2 1 Rad17 P-loop domain Zeta_toxin PF06414.12 OAP60962.1 - 0.018 14.3 0.0 0.031 13.5 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_22 PF13401.6 OAP60962.1 - 0.12 12.7 0.0 2 8.7 0.0 2.5 3 0 0 3 3 3 0 AAA domain Med18 PF09637.10 OAP60963.1 - 2.8e-41 142.0 0.0 3.2e-41 141.8 0.0 1.0 1 0 0 1 1 1 1 Med18 protein S36_mt PF10937.8 OAP60964.1 - 8.9e-37 127.2 1.6 2.2e-36 125.9 1.6 1.6 1 1 0 1 1 1 1 Ribosomal protein S36, mitochondrial BTG PF07742.12 OAP60965.1 - 0.13 12.2 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 BTG family RGS PF00615.19 OAP60966.1 - 2.4e-10 40.7 0.0 3.5e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain DUF647 PF04884.14 OAP60967.1 - 1.5e-88 296.5 0.6 2.1e-88 296.0 0.6 1.2 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis DUF5377 PF17347.2 OAP60967.1 - 0.015 15.6 0.0 0.032 14.6 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5377) ThaI PF15514.6 OAP60967.1 - 0.17 11.5 0.0 0.3 10.7 0.0 1.3 1 0 0 1 1 1 0 Restriction endonuclease ThaI PITH PF06201.13 OAP60970.1 - 2.8e-44 151.0 0.0 3.5e-44 150.7 0.0 1.1 1 0 0 1 1 1 1 PITH domain Snf7 PF03357.21 OAP60971.1 - 2.6e-30 105.3 13.0 2.6e-30 105.3 13.0 1.8 1 1 1 2 2 2 1 Snf7 MR_MLE_N PF02746.16 OAP60971.1 - 0.0095 16.1 0.6 0.026 14.8 0.1 1.9 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain GCIP PF13324.6 OAP60971.1 - 1.8 8.1 8.5 0.33 10.5 1.7 2.0 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting Abhydrolase_2 PF02230.16 OAP60972.1 - 4.1e-10 39.9 0.0 4.2e-07 30.0 0.0 2.3 2 1 0 2 2 2 2 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 OAP60972.1 - 5.2e-10 39.2 0.1 8.3e-05 22.2 0.1 2.3 1 1 1 2 2 2 2 Prolyl oligopeptidase family Esterase_phd PF10503.9 OAP60972.1 - 3.1e-08 33.4 0.0 0.00019 21.0 0.0 3.3 2 1 1 3 3 3 2 Esterase PHB depolymerase DLH PF01738.18 OAP60972.1 - 1.7e-07 31.1 0.0 3.2e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Dienelactone hydrolase family Esterase PF00756.20 OAP60972.1 - 6.7e-07 29.2 0.0 0.00035 20.3 0.0 2.4 2 0 0 2 2 2 2 Putative esterase Hydrolase_4 PF12146.8 OAP60972.1 - 1.8e-06 27.4 0.5 0.00044 19.6 0.1 2.5 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OAP60972.1 - 0.0035 18.0 4.1 0.0081 16.8 2.6 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAP60972.1 - 0.11 12.1 0.1 0.48 10.0 0.0 1.8 1 1 1 2 2 2 0 alpha/beta hydrolase fold Zn_clus PF00172.18 OAP60973.1 - 1e-07 31.9 8.7 2.3e-07 30.8 8.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 OAP60973.1 - 0.18 10.6 3.4 0.24 10.1 3.4 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain MFS_1 PF07690.16 OAP60974.1 - 5.6e-43 147.2 46.3 5.6e-43 147.2 46.3 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 OAP60974.1 - 1.6e-10 40.0 24.5 2.8e-10 39.2 24.5 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 OAP60974.1 - 1.4e-06 27.4 14.6 1.4e-06 27.4 14.6 4.4 4 1 0 4 4 4 2 Sugar (and other) transporter OATP PF03137.20 OAP60974.1 - 0.0014 17.0 4.9 0.0014 17.0 4.9 2.4 2 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family EMP24_GP25L PF01105.24 OAP60975.1 - 5.1e-40 137.3 0.1 6.2e-40 137.1 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD p450 PF00067.22 OAP60976.1 - 1.6e-63 215.1 0.0 2.5e-63 214.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans_2 PF11951.8 OAP60976.1 - 4.1e-13 48.9 2.9 7.6e-13 48.0 2.9 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Band_7 PF01145.25 OAP60976.1 - 0.07 13.1 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 SPFH domain / Band 7 family Sugar_tr PF00083.24 OAP60977.1 - 2.2e-86 290.5 23.1 2.7e-86 290.2 23.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP60977.1 - 3e-15 56.0 46.9 1.5e-08 34.0 18.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Mur_ligase PF01225.25 OAP60977.1 - 0.14 12.5 0.2 1.2 9.5 0.0 2.7 3 0 0 3 3 3 0 Mur ligase family, catalytic domain Sugar_tr PF00083.24 OAP60978.1 - 2.5e-121 405.7 19.1 2.8e-121 405.5 19.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP60978.1 - 1.7e-26 93.0 50.2 2.3e-24 86.0 24.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Ilm1 PF10311.9 OAP60978.1 - 0.15 11.7 0.5 0.33 10.6 0.1 1.7 2 0 0 2 2 2 0 Increased loss of mitochondrial DNA protein 1 Lipase_GDSL PF00657.22 OAP60980.1 - 4.9e-11 43.0 0.0 6.7e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 OAP60980.1 - 0.05 14.0 7.6 0.075 13.4 5.6 2.2 2 1 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family Peptidase_M28 PF04389.17 OAP60982.1 - 1.7e-33 116.0 0.0 2.7e-33 115.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 DUF4173 PF13777.6 OAP60982.1 - 0.0025 17.3 9.7 0.0025 17.3 9.7 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF4173) Peptidase_M20 PF01546.28 OAP60982.1 - 0.077 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 HSP70 PF00012.20 OAP60983.1 - 0.25 9.5 0.1 3 5.9 0.0 2.0 2 0 0 2 2 2 0 Hsp70 protein Presenilin PF01080.17 OAP60984.1 - 0.064 12.0 1.0 0.085 11.6 1.0 1.2 1 0 0 1 1 1 0 Presenilin Rad10 PF03834.14 OAP60985.1 - 3.4e-49 165.6 0.2 6e-49 164.8 0.2 1.4 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.6 OAP60985.1 - 0.004 17.7 0.2 0.012 16.1 0.0 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH PF00633.23 OAP60985.1 - 0.0086 15.9 0.1 0.02 14.8 0.1 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_2 PF12826.7 OAP60985.1 - 0.023 14.8 1.2 0.087 12.9 0.0 2.4 3 0 0 3 3 3 0 Helix-hairpin-helix motif ssDNA_DBD PF18333.1 OAP60985.1 - 0.026 14.6 0.5 0.056 13.5 0.5 1.5 1 0 0 1 1 1 0 Non-canonical single-stranded DNA-binding domain RRM_1 PF00076.22 OAP60986.1 - 1e-40 137.4 0.2 2.4e-16 59.3 0.0 5.5 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OAP60986.1 - 0.0025 17.4 0.0 1.6 8.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) XRN_M PF17846.1 OAP60986.1 - 0.069 12.1 5.0 0.15 10.9 5.0 1.6 1 0 0 1 1 1 0 Xrn1 helical domain Cyt-b5 PF00173.28 OAP60987.1 - 8.8e-09 35.4 0.0 1.1e-08 35.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Arginase PF00491.21 OAP60988.1 - 7.1e-78 261.9 0.5 9.4e-78 261.5 0.5 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 OAP60988.1 - 0.16 12.2 0.2 0.26 11.5 0.2 1.3 1 0 0 1 1 1 0 UPF0489 domain AA_permease PF00324.21 OAP60989.1 - 7.3e-113 377.7 34.2 8.9e-113 377.4 34.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAP60989.1 - 3.8e-19 68.8 37.8 5.1e-19 68.4 37.8 1.1 1 0 0 1 1 1 1 Amino acid permease Ycf70 PF17382.2 OAP60989.1 - 0.1 13.0 0.7 20 5.6 0.0 2.8 2 0 0 2 2 2 0 Uncharacterized Ycf70-like Orthoreo_P10 PF07204.11 OAP60989.1 - 0.52 10.3 2.7 1.7 8.7 2.7 1.9 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 DUF3602 PF12223.8 OAP60990.1 - 6.8e-10 39.4 11.8 4.9e-05 23.8 1.6 3.4 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) zf-C2H2 PF00096.26 OAP60991.1 - 0.015 15.7 3.2 0.043 14.3 3.2 1.9 1 0 0 1 1 1 0 Zinc finger, C2H2 type DNA_pol_phi PF04931.13 OAP60991.1 - 0.23 9.5 1.7 0.33 9.0 1.7 1.2 1 0 0 1 1 1 0 DNA polymerase phi Abhydrolase_1 PF00561.20 OAP60992.1 - 3.3e-10 40.0 0.0 0.00012 21.9 0.0 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAP60992.1 - 1.1e-09 39.3 0.2 1.4e-09 38.9 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAP60992.1 - 1.9e-08 33.9 0.1 0.00022 20.6 0.1 2.4 2 1 0 2 2 2 2 Serine aminopeptidase, S33 PGAP1 PF07819.13 OAP60992.1 - 0.022 14.5 0.0 0.03 14.0 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_2 PF02230.16 OAP60992.1 - 0.029 14.2 0.0 2 8.2 0.0 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase IN_DBD_C PF00552.21 OAP60992.1 - 0.12 11.7 0.0 0.25 10.6 0.0 1.5 1 0 0 1 1 1 0 Integrase DNA binding domain Pam16 PF03656.13 OAP60993.1 - 4.1e-08 33.3 0.1 8.8e-08 32.2 0.1 1.5 1 1 0 1 1 1 1 Pam16 DnaJ PF00226.31 OAP60993.1 - 6.3e-05 23.0 0.0 0.0001 22.4 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain DUF3918 PF13056.6 OAP60993.1 - 0.012 15.2 0.5 0.025 14.2 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3918) SMBP PF16785.5 OAP60994.1 - 0.072 13.3 0.3 0.19 12.0 0.3 1.6 1 0 0 1 1 1 0 Small metal-binding protein AA_permease_2 PF13520.6 OAP60995.1 - 4.3e-49 167.5 50.5 5.6e-49 167.1 50.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAP60995.1 - 1.4e-21 76.7 44.2 1.7e-21 76.4 44.2 1.0 1 0 0 1 1 1 1 Amino acid permease PetN PF03742.14 OAP60995.1 - 0.0028 17.5 2.2 0.024 14.5 2.2 2.7 1 0 0 1 1 1 1 PetN Hemerythrin PF01814.23 OAP60996.1 - 2e-11 44.6 0.9 2.7e-11 44.2 0.9 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain TCTP PF00838.17 OAP60996.1 - 0.0073 16.7 0.1 0.0092 16.3 0.1 1.2 1 0 0 1 1 1 1 Translationally controlled tumour protein MARVEL PF01284.23 OAP60997.1 - 6.9e-07 29.4 9.5 1.4e-06 28.4 9.5 1.4 1 0 0 1 1 1 1 Membrane-associating domain DUF3425 PF11905.8 OAP60998.1 - 5.2e-17 62.0 0.0 1e-16 61.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Zn_clus PF00172.18 OAP60998.1 - 4.6e-09 36.2 6.5 8e-09 35.5 6.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_L24e PF01246.20 OAP60999.1 - 2.2e-29 101.5 4.7 4.7e-29 100.4 4.7 1.6 1 0 0 1 1 1 1 Ribosomal protein L24e DUF2175 PF09943.9 OAP60999.1 - 0.62 10.4 4.8 1.1 9.5 0.4 2.4 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) APG6_N PF17675.1 OAP60999.1 - 1.2 9.7 5.5 2.1 8.9 5.5 1.5 1 1 0 1 1 1 0 Apg6 coiled-coil region Sugar_tr PF00083.24 OAP61000.1 - 2.8e-78 263.8 18.4 3.2e-78 263.6 18.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP61000.1 - 2.3e-12 46.5 29.5 2.3e-12 46.5 29.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2574 PF10836.8 OAP61000.1 - 0.05 13.5 1.6 0.054 13.4 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2574) Zn_clus PF00172.18 OAP61001.1 - 2.2e-05 24.5 9.3 2.2e-05 24.5 9.3 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAP61001.1 - 0.034 13.2 0.0 0.055 12.5 0.0 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain Integrase_H2C2 PF17921.1 OAP61001.1 - 0.15 12.2 1.4 0.33 11.1 1.4 1.6 1 0 0 1 1 1 0 Integrase zinc binding domain adh_short PF00106.25 OAP61002.1 - 1.8e-16 60.2 0.0 2.9e-15 56.2 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP61002.1 - 2e-09 37.3 0.0 3.8e-09 36.4 0.0 1.4 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase GDP_Man_Dehyd PF16363.5 OAP61002.1 - 0.0068 15.8 0.0 0.036 13.4 0.0 1.8 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 OAP61002.1 - 0.074 12.5 0.0 0.29 10.6 0.0 1.7 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family KR PF08659.10 OAP61002.1 - 0.09 12.7 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 KR domain Pmp3 PF01679.17 OAP61002.1 - 0.21 11.8 0.5 0.44 10.8 0.5 1.5 1 0 0 1 1 1 0 Proteolipid membrane potential modulator NAD_binding_10 PF13460.6 OAP61003.1 - 2.1e-07 31.0 0.0 2.6e-07 30.7 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 OAP61003.1 - 0.00038 19.7 0.0 0.075 12.2 0.0 2.5 2 1 1 3 3 3 2 Male sterility protein 3Beta_HSD PF01073.19 OAP61003.1 - 0.0063 15.5 0.0 0.013 14.5 0.0 1.5 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 OAP61003.1 - 0.014 14.5 0.0 0.083 12.0 0.0 1.9 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.24 OAP61003.1 - 0.014 15.8 0.0 0.035 14.6 0.0 1.7 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.21 OAP61003.1 - 0.042 13.3 0.0 0.06 12.8 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family KR PF08659.10 OAP61003.1 - 0.084 12.8 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 KR domain Fungal_trans_2 PF11951.8 OAP61004.1 - 1.2e-08 34.3 2.9 4.3e-07 29.1 2.9 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Abhydrolase_1 PF00561.20 OAP61005.1 - 1.2e-17 64.4 0.2 1.7e-16 60.7 0.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAP61005.1 - 8e-12 44.9 0.0 3.7e-11 42.8 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OAP61005.1 - 3.1e-09 37.8 0.8 3.7e-09 37.5 0.8 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family PhyH PF05721.13 OAP61006.1 - 6.1e-23 82.2 0.1 7.6e-23 81.9 0.1 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 OAP61006.1 - 0.002 18.5 0.1 0.008 16.6 0.0 2.0 2 1 1 3 3 3 1 Putative 2OG-Fe(II) oxygenase RE_Bsp6I PF09504.10 OAP61007.1 - 0.082 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Bsp6I restriction endonuclease CDP-OH_P_transf PF01066.21 OAP61008.1 - 2.2e-17 63.6 0.1 2.2e-17 63.6 0.1 3.5 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Zn_Tnp_IS1595 PF12760.7 OAP61009.1 - 0.017 15.1 1.1 0.03 14.3 1.1 1.3 1 0 0 1 1 1 0 Transposase zinc-ribbon domain OrfB_Zn_ribbon PF07282.11 OAP61009.1 - 0.078 12.9 1.1 0.14 12.1 1.1 1.4 1 0 0 1 1 1 0 Putative transposase DNA-binding domain PRIMA1 PF16101.5 OAP61009.1 - 1.2 9.2 6.2 2.1 8.4 6.2 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Ribosomal_L13 PF00572.18 OAP61010.1 - 6e-11 42.7 0.0 5.9e-09 36.2 0.0 2.4 1 1 0 1 1 1 1 Ribosomal protein L13 WD40 PF00400.32 OAP61011.1 - 3.9e-12 46.5 14.3 0.00017 22.3 1.6 4.8 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAP61011.1 - 1.3e-07 31.8 0.2 0.14 12.5 0.0 4.6 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 OAP61011.1 - 0.00018 20.4 0.4 2.5 6.7 0.0 3.4 1 1 1 3 3 3 2 Nup133 N terminal like Frtz PF11768.8 OAP61011.1 - 0.015 13.6 0.0 0.041 12.2 0.0 1.6 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz PQQ_3 PF13570.6 OAP61011.1 - 0.023 15.2 0.4 29 5.3 0.0 4.0 4 1 1 5 5 5 0 PQQ-like domain Nup160 PF11715.8 OAP61011.1 - 0.034 12.8 3.0 1.7 7.2 0.3 3.1 1 1 2 3 3 3 0 Nucleoporin Nup120/160 adh_short PF00106.25 OAP61012.1 - 3.6e-22 78.8 0.0 1.1e-19 70.7 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAP61012.1 - 6e-12 45.6 0.0 7e-10 38.8 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP61012.1 - 3.4e-09 36.9 0.2 5.6e-09 36.1 0.2 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAP61012.1 - 0.068 12.6 0.0 0.089 12.2 0.0 1.1 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Toprim_4 PF13662.6 OAP61012.1 - 0.17 12.4 0.2 25 5.4 0.0 2.4 1 1 1 2 2 2 0 Toprim domain YchF-GTPase_C PF06071.13 OAP61013.1 - 2.6e-35 120.5 0.2 6.5e-35 119.2 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 OAP61013.1 - 1.4e-15 57.4 0.0 3.8e-15 56.0 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OAP61013.1 - 0.00053 19.5 0.0 0.0011 18.5 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.21 OAP61013.1 - 0.0023 18.0 0.0 0.0072 16.4 0.0 1.8 2 0 0 2 2 2 1 TGS domain DUF4609 PF15382.6 OAP61013.1 - 0.15 11.9 0.0 0.38 10.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4609) SecA_PP_bind PF01043.20 OAP61013.1 - 0.28 11.8 1.0 0.46 11.2 0.1 1.9 2 1 0 2 2 2 0 SecA preprotein cross-linking domain Glyco_transf_15 PF01793.16 OAP61014.1 - 9.6e-95 317.6 1.2 1.3e-94 317.2 1.2 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Hira PF07569.11 OAP61015.1 - 1e-83 280.4 0.0 2.9e-83 279.0 0.0 1.8 2 0 0 2 2 2 1 TUP1-like enhancer of split WD40 PF00400.32 OAP61015.1 - 9.2e-29 99.1 16.3 1.7e-05 25.5 0.0 8.2 7 1 1 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAP61015.1 - 6.5e-15 55.2 0.0 0.024 14.9 0.0 5.9 4 2 2 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain HIRA_B PF09453.10 OAP61015.1 - 7.2e-08 32.1 0.2 2.1e-07 30.6 0.2 1.9 1 0 0 1 1 1 1 HIRA B motif Ge1_WD40 PF16529.5 OAP61015.1 - 0.0011 17.9 0.2 0.93 8.4 0.0 4.3 4 2 2 6 6 6 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 OAP61015.1 - 0.01 15.8 2.9 0.79 9.7 0.2 3.9 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Band_7 PF01145.25 OAP61016.1 - 8.6e-31 107.3 1.4 1.7e-30 106.4 1.4 1.5 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_C PF16200.5 OAP61016.1 - 1.7e-24 85.6 1.9 5e-24 84.1 1.9 1.9 1 0 0 1 1 1 1 C-terminal region of band_7 Pox_A11 PF05061.13 OAP61016.1 - 0.038 13.3 0.2 0.061 12.6 0.2 1.3 1 0 0 1 1 1 0 Poxvirus A11 Protein Band_7_1 PF13421.6 OAP61016.1 - 0.065 12.9 0.2 0.15 11.8 0.0 1.7 2 0 0 2 2 2 0 SPFH domain-Band 7 family DRTGG PF07085.12 OAP61016.1 - 0.079 12.7 1.2 1 9.2 0.1 2.7 1 1 0 3 3 3 0 DRTGG domain Fungal_trans PF04082.18 OAP61017.1 - 8.3e-14 51.3 0.0 1.3e-13 50.6 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP61017.1 - 0.25 11.5 0.1 0.25 11.5 0.1 1.9 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Catalase PF00199.19 OAP61018.1 - 6.4e-150 499.5 0.4 1.7e-149 498.1 0.4 1.6 1 1 0 1 1 1 1 Catalase Catalase-rel PF06628.12 OAP61018.1 - 3.2e-10 40.1 0.3 7.3e-10 38.9 0.3 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive Carbpep_Y_N PF05388.11 OAP61018.1 - 0.45 11.0 1.9 1 9.9 0.2 2.2 2 0 0 2 2 2 0 Carboxypeptidase Y pro-peptide Oxidored_molyb PF00174.19 OAP61019.1 - 2.8e-43 147.5 0.0 5.1e-43 146.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 OAP61019.1 - 1.5e-19 70.4 3.7 3.1e-19 69.4 3.7 1.5 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain muHD PF10291.9 OAP61019.1 - 0.053 12.9 0.3 0.087 12.3 0.3 1.2 1 0 0 1 1 1 0 Muniscin C-terminal mu homology domain Cytochrom_B561 PF03188.16 OAP61020.1 - 0.00015 21.9 7.2 0.00015 21.9 7.2 1.8 1 1 1 2 2 2 2 Eukaryotic cytochrome b561 ETRAMP PF09716.10 OAP61020.1 - 0.072 13.2 5.0 3.3 7.9 0.1 3.0 2 1 1 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) PRA1 PF03208.19 OAP61020.1 - 1.2 8.7 6.7 0.29 10.7 0.2 2.6 2 1 1 3 3 3 0 PRA1 family protein DUF2427 PF10348.9 OAP61020.1 - 8.3 6.3 9.3 11 5.8 6.5 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF2427) MFS_1 PF07690.16 OAP61021.1 - 1.7e-30 106.1 18.1 2.3e-30 105.7 16.6 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1980 PF09323.10 OAP61021.1 - 0.1 12.5 0.0 22 4.9 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) UPF0242 PF06785.11 OAP61021.1 - 0.1 12.7 0.0 1.1 9.4 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF3993 PF13158.6 OAP61021.1 - 0.13 12.4 0.2 6.2 7.1 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3993) Wzy_C PF04932.15 OAP61021.1 - 3.2 7.4 10.1 1.2 8.7 0.1 3.4 2 2 1 3 3 3 0 O-Antigen ligase Fungal_trans PF04082.18 OAP61022.1 - 1.7e-06 27.3 0.0 3.1e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Tautomerase_3 PF14832.6 OAP61023.1 - 1.7e-08 34.7 0.0 3.1e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 Putative oxalocrotonate tautomerase enzyme COesterase PF00135.28 OAP61024.1 - 5.3e-58 197.1 0.0 6.8e-58 196.8 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAP61024.1 - 4.4e-05 23.4 0.0 0.019 14.8 0.0 2.6 2 0 0 2 2 2 2 alpha/beta hydrolase fold Pkinase PF00069.25 OAP61025.1 - 2.5e-26 92.6 0.0 3.2e-26 92.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP61025.1 - 6.9e-14 51.7 0.0 9.6e-14 51.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAP61025.1 - 3.6e-09 35.9 0.0 6.5e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OAP61025.1 - 0.00018 21.5 0.0 0.0014 18.6 0.0 2.1 1 1 0 2 2 2 1 Phosphotransferase enzyme family AhpC-TSA PF00578.21 OAP61026.1 - 4e-23 81.7 0.0 7.2e-23 80.8 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 OAP61026.1 - 1.4e-13 50.8 0.0 2.3e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 OAP61026.1 - 0.012 15.7 0.0 0.021 14.9 0.0 1.4 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme Sedlin_N PF04628.13 OAP61027.1 - 4.1e-17 62.5 0.0 7.1e-17 61.8 0.0 1.3 1 1 0 1 1 1 1 Sedlin, N-terminal conserved region Oxidored_q6 PF01058.22 OAP61028.1 - 3.6e-22 78.6 0.0 6e-22 77.9 0.0 1.3 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit HMA PF00403.26 OAP61030.1 - 9.4e-18 64.4 1.7 1.1e-17 64.2 1.7 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain Fer2_BFD PF04324.15 OAP61030.1 - 0.061 13.7 0.2 0.25 11.7 0.1 1.9 2 0 0 2 2 2 0 BFD-like [2Fe-2S] binding domain DUF2293 PF10056.9 OAP61031.1 - 5.4e-29 100.3 0.1 1.6e-28 98.8 0.1 1.9 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2293) Hydrolase_4 PF12146.8 OAP61032.1 - 4.7e-10 39.1 0.0 6.1e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OAP61032.1 - 3.1e-07 30.3 0.0 1.5e-05 24.8 0.1 2.1 1 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAP61032.1 - 1.6e-05 25.6 0.1 1.8e-05 25.5 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.13 OAP61032.1 - 5.6e-05 23.1 0.1 0.00055 19.8 0.1 2.0 1 1 1 2 2 2 1 Serine hydrolase Thioesterase PF00975.20 OAP61032.1 - 8.3e-05 22.8 0.0 0.00013 22.2 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.13 OAP61032.1 - 0.00085 19.1 0.0 0.0013 18.5 0.0 1.3 1 1 0 1 1 1 1 PGAP1-like protein Esterase PF00756.20 OAP61032.1 - 0.0015 18.3 0.0 0.0019 17.9 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.16 OAP61032.1 - 0.0065 16.3 0.0 0.0089 15.9 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Acyl_transf_1 PF00698.21 OAP61032.1 - 0.009 15.5 0.1 0.011 15.3 0.1 1.1 1 0 0 1 1 1 1 Acyl transferase domain FSH1 PF03959.13 OAP61032.1 - 0.02 14.5 0.0 0.032 13.9 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.7 OAP61032.1 - 0.041 13.6 0.0 0.096 12.5 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase family TauD PF02668.16 OAP61033.1 - 8.2e-30 104.5 0.3 1.2e-29 103.9 0.3 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Zn_clus PF00172.18 OAP61034.1 - 6.8e-06 26.1 10.4 1.1e-05 25.4 10.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TauD PF02668.16 OAP61035.1 - 8e-34 117.6 0.1 1.2e-33 117.1 0.1 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DIOX_N PF14226.6 OAP61036.1 - 4.6e-28 98.4 0.0 7e-28 97.8 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OAP61036.1 - 7.3e-22 77.8 0.1 1.2e-21 77.0 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Ank_5 PF13857.6 OAP61037.1 - 1.1e-21 76.6 0.2 1e-07 32.1 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 OAP61037.1 - 1.8e-18 66.6 0.0 4.9e-06 27.0 0.0 4.4 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 OAP61037.1 - 8.1e-16 58.4 0.0 0.0012 19.4 0.0 3.2 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OAP61037.1 - 3e-11 42.5 0.0 0.16 12.6 0.0 4.7 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 OAP61037.1 - 2.2e-10 40.5 0.1 0.012 16.1 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat F-box PF00646.33 OAP61037.1 - 4.2e-05 23.3 0.0 7.9e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 OAP61037.1 - 0.00037 20.3 0.1 0.00073 19.4 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 OAP61037.1 - 0.0037 17.1 0.1 0.013 15.4 0.0 1.9 2 0 0 2 2 2 1 F-box HNH_2 PF13391.6 OAP61038.1 - 2e-10 40.6 0.0 3.7e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 HNH endonuclease BTHB PF18410.1 OAP61039.1 - 0.0061 16.3 0.2 0.92 9.4 0.1 2.3 2 0 0 2 2 2 2 Basic tilted helix bundle domain Complex1_LYR PF05347.15 OAP61039.1 - 0.012 15.7 2.8 0.012 15.7 2.8 1.9 2 0 0 2 2 2 0 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 OAP61039.1 - 0.044 14.5 2.9 0.087 13.6 3.0 1.7 1 1 0 1 1 1 0 Complex1_LYR-like DASH_Dad4 PF08650.10 OAP61039.1 - 0.092 12.7 0.3 0.21 11.6 0.2 1.7 1 1 0 1 1 1 0 DASH complex subunit Dad4 MFS_1 PF07690.16 OAP61040.1 - 1e-41 143.1 45.3 1e-41 143.1 45.3 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAP61040.1 - 2.1e-09 36.8 7.9 2.1e-09 36.8 7.9 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter Cluap1 PF10234.9 OAP61040.1 - 0.097 12.1 0.1 0.14 11.5 0.1 1.1 1 0 0 1 1 1 0 Clusterin-associated protein-1 AtuA PF07287.11 OAP61041.1 - 9.9e-133 442.2 0.0 1.2e-132 441.9 0.0 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA CoA_transf_3 PF02515.17 OAP61042.1 - 6.8e-39 134.0 0.0 1e-35 123.6 0.0 2.2 2 0 0 2 2 2 2 CoA-transferase family III HSP20 PF00011.21 OAP61044.1 - 3.9e-20 71.9 1.3 9.6e-15 54.6 0.2 2.1 1 1 1 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 OAP61044.1 - 1.5e-05 24.5 0.1 8e-05 22.1 0.1 2.0 1 1 0 1 1 1 1 HSP20-like domain found in ArsA HSP20 PF00011.21 OAP61046.1 - 3.4e-09 36.8 0.0 4.1e-08 33.3 0.0 2.1 2 0 0 2 2 2 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 OAP61046.1 - 0.00093 18.7 0.0 0.0051 16.3 0.0 2.0 2 0 0 2 2 2 1 HSP20-like domain found in ArsA HLH PF00010.26 OAP61047.1 - 7.2e-09 35.5 0.0 1.6e-08 34.3 0.0 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain HNH_2 PF13391.6 OAP61049.1 - 0.0008 19.5 0.0 0.0017 18.5 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease Nop14 PF04147.12 OAP61050.1 - 0.11 10.7 4.3 0.13 10.4 4.3 1.1 1 0 0 1 1 1 0 Nop14-like family DARPP-32 PF05395.12 OAP61050.1 - 0.17 12.1 6.1 0.26 11.5 6.1 1.3 1 0 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 SDA1 PF05285.12 OAP61050.1 - 8.9 5.6 10.6 12 5.2 10.6 1.1 1 0 0 1 1 1 0 SDA1 Acetyltransf_3 PF13302.7 OAP61051.1 - 3.8e-16 60.0 0.1 2.5e-15 57.3 0.1 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAP61051.1 - 4.9e-05 23.5 0.1 7.9e-05 22.9 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 OAP61051.1 - 0.0051 16.5 0.1 0.0097 15.6 0.0 1.6 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain zf-CHCC PF10276.9 OAP61051.1 - 0.12 12.5 0.1 0.23 11.6 0.1 1.4 1 0 0 1 1 1 0 Zinc-finger domain Ion_trans PF00520.31 OAP61053.1 - 9.7e-10 38.1 1.6 1.2e-09 37.7 1.6 1.1 1 0 0 1 1 1 1 Ion transport protein CCDC85 PF10226.9 OAP61053.1 - 0.011 15.4 0.2 0.019 14.7 0.2 1.3 1 0 0 1 1 1 0 CCDC85 family DUF5082 PF16888.5 OAP61053.1 - 0.011 16.0 0.6 0.019 15.3 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) ZapB PF06005.12 OAP61053.1 - 0.019 15.4 0.2 0.031 14.7 0.2 1.3 1 0 0 1 1 1 0 Cell division protein ZapB DHR10 PF18595.1 OAP61053.1 - 0.034 14.2 0.6 0.053 13.6 0.6 1.2 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain YabA PF06156.13 OAP61053.1 - 0.043 14.4 0.0 0.09 13.4 0.0 1.5 1 0 0 1 1 1 0 Initiation control protein YabA Med21 PF11221.8 OAP61053.1 - 0.058 13.7 1.5 0.096 12.9 1.5 1.3 1 0 0 1 1 1 0 Subunit 21 of Mediator complex TSC22 PF01166.18 OAP61053.1 - 0.19 12.0 0.5 0.34 11.3 0.5 1.3 1 0 0 1 1 1 0 TSC-22/dip/bun family MLANA PF14991.6 OAP61054.1 - 8.3 6.7 6.4 1.9 8.8 2.7 1.7 1 1 1 2 2 2 0 Protein melan-A HpcH_HpaI PF03328.14 OAP61055.1 - 4.8e-31 107.6 0.0 6.4e-31 107.2 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PEP-utilizers_C PF02896.18 OAP61055.1 - 0.027 13.6 0.2 0.07 12.2 0.3 1.6 2 1 0 2 2 2 0 PEP-utilising enzyme, TIM barrel domain ADH_zinc_N PF00107.26 OAP61055.1 - 0.056 13.4 0.8 1.3 9.0 0.1 2.5 2 1 0 2 2 2 0 Zinc-binding dehydrogenase PK PF00224.21 OAP61055.1 - 0.059 12.3 0.1 0.085 11.7 0.1 1.1 1 0 0 1 1 1 0 Pyruvate kinase, barrel domain PcF PF09461.10 OAP61055.1 - 0.13 12.6 0.0 0.28 11.6 0.0 1.5 1 0 0 1 1 1 0 Phytotoxin PcF protein Aminotran_3 PF00202.21 OAP61056.1 - 8.1e-124 413.4 0.0 9.5e-124 413.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 OAP61056.1 - 0.13 11.4 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II Spt4 PF06093.13 OAP61057.1 - 4.2e-32 110.1 0.2 5e-32 109.8 0.2 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger PPP5 PF08321.12 OAP61058.1 - 1.1e-33 115.3 0.5 2.9e-33 114.0 0.5 1.7 1 0 0 1 1 1 1 PPP5 TPR repeat region Metallophos PF00149.28 OAP61058.1 - 1.6e-30 107.1 0.1 2.4e-30 106.6 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_1 PF00515.28 OAP61058.1 - 3.4e-09 36.1 9.1 0.00071 19.3 0.4 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 OAP61058.1 - 1.1e-07 31.4 7.9 0.011 15.8 0.5 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 OAP61058.1 - 5e-06 26.1 7.5 0.0064 16.2 0.9 3.4 2 1 1 3 3 3 2 TPR repeat TPR_16 PF13432.6 OAP61058.1 - 0.0012 19.4 2.6 4.2 8.1 5.5 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 OAP61058.1 - 0.0019 18.9 1.2 3.7 8.6 0.2 3.2 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 OAP61058.1 - 0.0019 18.6 1.9 0.96 10.0 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 OAP61058.1 - 0.014 15.7 2.6 2.4 8.7 0.5 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 OAP61058.1 - 0.029 14.5 0.1 0.44 10.7 0.1 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 OAP61058.1 - 0.044 14.4 0.6 17 6.3 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 OAP61058.1 - 0.55 10.6 7.0 0.32 11.3 0.7 3.0 3 0 0 3 3 2 0 Tetratricopeptide repeat MIT PF04212.18 OAP61058.1 - 4 7.6 7.0 14 5.9 0.2 3.0 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain F-box PF00646.33 OAP61059.1 - 0.004 17.0 0.0 0.012 15.5 0.0 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 OAP61059.1 - 0.049 13.5 0.1 0.13 12.1 0.1 1.7 1 0 0 1 1 1 0 F-box-like DUF3669 PF12417.8 OAP61061.1 - 2.8e-16 59.5 0.1 2.8e-16 59.5 0.1 1.8 2 0 0 2 2 2 1 Zinc finger protein AMP-binding PF00501.28 OAP61062.1 - 7.5e-77 258.7 0.0 1e-76 258.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAP61062.1 - 1.2e-10 42.2 1.2 2.4e-10 41.2 0.6 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain bMG3 PF11974.8 OAP61062.1 - 0.13 12.3 0.0 0.32 11.0 0.0 1.7 1 0 0 1 1 1 0 Bacterial alpha-2-macroglobulin MG3 domain CMD PF02627.20 OAP61063.1 - 0.0007 19.6 2.1 0.78 9.8 0.2 2.6 2 0 0 2 2 2 2 Carboxymuconolactone decarboxylase family zf_Hakai PF18408.1 OAP61063.1 - 0.3 10.8 0.1 0.3 10.8 0.1 2.0 2 0 0 2 2 2 0 C2H2 Hakai zinc finger domain Pep3_Vps18 PF05131.14 OAP61064.1 - 1.1e-44 151.9 0.0 7.9e-44 149.1 0.0 2.4 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 OAP61064.1 - 1.5e-09 37.8 9.4 2.8e-06 27.3 0.1 3.5 3 1 0 3 3 3 2 Region in Clathrin and VPS Vps39_2 PF10367.9 OAP61064.1 - 8.6e-05 22.9 0.1 0.00018 21.9 0.1 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 zf-C3HC4_2 PF13923.6 OAP61064.1 - 0.00029 20.6 0.5 0.00083 19.2 0.5 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 OAP61064.1 - 0.00043 19.8 0.3 0.001 18.6 0.3 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_2 PF13639.6 OAP61064.1 - 0.00071 19.9 0.9 0.0021 18.4 0.9 1.9 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 OAP61064.1 - 0.0015 18.5 0.5 0.0037 17.2 0.5 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 OAP61064.1 - 0.0022 17.7 4.6 0.0022 17.7 4.6 2.4 2 0 0 2 2 2 1 RING-like zinc finger DUF2175 PF09943.9 OAP61064.1 - 0.0078 16.5 0.3 0.03 14.6 0.0 2.1 2 0 0 2 2 1 1 Uncharacterized protein conserved in archaea (DUF2175) zf-RING_UBOX PF13445.6 OAP61064.1 - 0.014 15.4 1.0 0.034 14.2 1.0 1.7 1 0 0 1 1 1 0 RING-type zinc-finger RPN1_RPN2_N PF17781.1 OAP61064.1 - 0.02 14.3 0.2 0.041 13.3 0.2 1.5 1 0 0 1 1 1 0 RPN1/RPN2 N-terminal domain zf-rbx1 PF12678.7 OAP61064.1 - 0.027 14.7 0.1 0.23 11.8 0.3 2.3 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 OAP61064.1 - 0.03 14.2 0.3 0.074 12.9 0.3 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PspA_IM30 PF04012.12 OAP61064.1 - 0.28 10.7 4.2 0.27 10.8 0.1 2.6 3 0 0 3 3 3 0 PspA/IM30 family MFS_1 PF07690.16 OAP61065.1 - 1.3e-30 106.5 36.0 1.3e-30 106.5 36.0 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Spo12 PF05032.12 OAP61066.1 - 5.3e-10 39.0 0.2 1.7e-09 37.4 0.2 1.9 1 0 0 1 1 1 1 Spo12 family KdpD PF02702.17 OAP61066.1 - 0.024 14.1 0.1 0.029 13.9 0.1 1.1 1 0 0 1 1 1 0 Osmosensitive K+ channel His kinase sensor domain PQ-loop PF04193.14 OAP61067.1 - 1.3e-39 133.7 9.8 3.6e-21 74.7 1.5 2.6 2 0 0 2 2 2 2 PQ loop repeat HTH_Bact PF18768.1 OAP61067.1 - 0.19 11.3 0.3 0.7 9.5 0.1 2.0 2 0 0 2 2 2 0 Helix-turn-helix bacterial domain HemX PF04375.14 OAP61067.1 - 0.22 10.8 0.1 0.33 10.2 0.1 1.2 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF3585 PF12130.8 OAP61068.1 - 0.0051 16.9 1.7 0.009 16.2 1.7 1.3 1 0 0 1 1 1 1 Bivalent Mical/EHBP Rab binding domain Paralemmin PF03285.15 OAP61068.1 - 0.028 14.0 0.4 0.028 14.0 0.4 2.0 2 0 0 2 2 2 0 Paralemmin Zn_clus PF00172.18 OAP61069.1 - 1.2e-06 28.6 8.6 4e-06 26.9 8.6 2.0 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PUF PF00806.19 OAP61070.1 - 1.6e-58 191.2 18.0 2.1e-09 36.6 0.2 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat DUF234 PF03008.14 OAP61070.1 - 0.14 12.6 0.2 0.35 11.3 0.2 1.6 1 0 0 1 1 1 0 Archaea bacterial proteins of unknown function Importin_rep_3 PF18806.1 OAP61070.1 - 0.24 11.5 0.6 81 3.4 0.0 3.2 1 1 2 3 3 3 0 Importin 13 repeat sCache_2 PF17200.4 OAP61070.1 - 0.3 10.9 1.6 92 2.8 0.0 4.0 5 0 0 5 5 5 0 Single Cache domain 2 Toxin_38 PF14866.6 OAP61070.1 - 0.46 10.8 1.1 6.4 7.2 0.1 2.4 2 0 0 2 2 2 0 Potassium channel toxin Mcp5_PH PF12814.7 OAP61072.1 - 4.3e-45 152.8 0.1 8.7e-45 151.8 0.1 1.6 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology PH PF00169.29 OAP61072.1 - 5.2e-06 26.9 0.0 1.3e-05 25.6 0.0 1.7 1 0 0 1 1 1 1 PH domain Tup_N PF08581.10 OAP61072.1 - 0.96 9.8 11.6 1.1 9.6 0.1 3.9 3 0 0 3 3 3 0 Tup N-terminal MbeD_MobD PF04899.12 OAP61072.1 - 1.3 9.2 7.8 0.088 12.9 1.2 2.6 3 0 0 3 3 3 0 MbeD/MobD like CLTH PF10607.9 OAP61073.1 - 1.9e-29 102.4 0.1 4.8e-29 101.2 0.0 1.7 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 OAP61073.1 - 3.9e-05 23.4 0.0 0.0001 22.1 0.0 1.8 1 0 0 1 1 1 1 LisH RRP36 PF06102.12 OAP61073.1 - 0.072 13.1 2.1 0.15 12.0 2.1 1.4 1 0 0 1 1 1 0 rRNA biogenesis protein RRP36 PhyH PF05721.13 OAP61075.1 - 1e-06 29.2 0.2 2.7e-06 27.8 0.2 1.7 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Fungal_trans_2 PF11951.8 OAP61076.1 - 0.042 12.6 0.1 0.06 12.1 0.1 1.1 1 0 0 1 1 1 0 Fungal specific transcription factor domain SSF PF00474.17 OAP61079.1 - 1.4e-21 76.8 28.3 2.3e-21 76.1 28.3 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family LapA_dom PF06305.11 OAP61080.1 - 0.023 14.5 0.1 0.042 13.7 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain F1F0-ATPsyn_F PF10791.9 OAP61080.1 - 0.16 12.5 0.0 0.32 11.5 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial F1-F0 ATP synthase subunit F of fungi SSB PF00436.25 OAP61081.1 - 1.4e-14 54.0 0.0 1.8e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 Single-strand binding protein family STE3 PF02076.15 OAP61082.1 - 4.1e-72 242.8 12.2 4.8e-72 242.6 12.2 1.0 1 0 0 1 1 1 1 Pheromone A receptor DHHC PF01529.20 OAP61082.1 - 0.76 9.9 4.2 0.55 10.3 1.8 2.1 1 1 1 2 2 2 0 DHHC palmitoyltransferase DUF4231 PF14015.6 OAP61082.1 - 0.94 10.0 7.0 2.5 8.6 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) PhaG_MnhG_YufB PF03334.14 OAP61082.1 - 1.8 8.8 8.7 0.089 13.0 2.1 2.2 2 0 0 2 2 2 0 Na+/H+ antiporter subunit HSBP1 PF06825.12 OAP61083.1 - 0.0086 15.9 1.0 0.079 12.8 0.3 2.3 2 0 0 2 2 2 1 Heat shock factor binding protein 1 Vip3A_N PF12495.8 OAP61083.1 - 0.027 14.4 0.2 0.056 13.3 0.1 1.5 1 1 1 2 2 2 0 Vegetative insecticide protein 3A N terminal Sugarporin_N PF11471.8 OAP61083.1 - 0.056 13.4 0.6 0.056 13.4 0.6 2.2 3 0 0 3 3 3 0 Maltoporin periplasmic N-terminal extension Syntaxin-6_N PF09177.11 OAP61083.1 - 3.5 8.3 5.6 12 6.5 0.3 2.9 2 1 1 3 3 3 0 Syntaxin 6, N-terminal GSH_synth_ATP PF03917.17 OAP61084.1 - 2.2e-135 451.2 0.0 2.5e-135 451.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 OAP61084.1 - 3.7e-30 104.4 0.0 6.2e-30 103.7 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic glutathione synthase SNF2_N PF00176.23 OAP61085.1 - 1.9e-46 158.4 0.8 3.9e-46 157.4 0.8 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OAP61085.1 - 2.4e-18 66.5 0.0 6.2e-18 65.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAP61085.1 - 1.6e-07 31.4 1.2 3.7e-07 30.3 0.0 2.3 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit SAM_2 PF07647.17 OAP61085.1 - 1.7e-05 24.9 0.0 3.7e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) LIDHydrolase PF10230.9 OAP61086.1 - 2.2e-49 168.4 0.0 2.3e-39 135.5 0.0 2.5 2 1 0 2 2 2 2 Lipid-droplet associated hydrolase Thioesterase PF00975.20 OAP61086.1 - 0.057 13.5 0.0 0.057 13.5 0.0 2.0 3 0 0 3 3 3 0 Thioesterase domain PGAP1 PF07819.13 OAP61086.1 - 0.15 11.8 2.9 0.1 12.3 0.6 1.9 2 0 0 2 2 2 0 PGAP1-like protein Peptidase_S49_N PF08496.10 OAP61086.1 - 0.35 10.9 0.1 0.35 10.9 0.1 1.7 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Abhydrolase_6 PF12697.7 OAP61086.1 - 0.44 11.1 12.1 0.45 11.1 6.8 2.5 2 1 0 2 2 2 0 Alpha/beta hydrolase family Presenilin PF01080.17 OAP61086.1 - 0.48 9.1 4.1 0.77 8.5 4.1 1.4 1 0 0 1 1 1 0 Presenilin Neur_chan_memb PF02932.16 OAP61086.1 - 0.88 9.6 2.5 2.3 8.2 2.5 1.7 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CDC45 PF02724.14 OAP61086.1 - 1.6 7.0 6.9 2.4 6.4 6.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Suf PF05843.14 OAP61086.1 - 1.7 8.6 5.3 3.8 7.4 5.3 1.5 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF3464 PF11947.8 OAP61086.1 - 9.8 5.9 6.8 20 4.9 0.7 2.3 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 DCP1 PF06058.13 OAP61087.1 - 2e-25 89.0 0.0 2.7e-25 88.6 0.0 1.2 1 0 0 1 1 1 1 Dcp1-like decapping family LCE6A PF15858.5 OAP61087.1 - 0.33 11.7 2.5 1 10.2 2.5 1.8 1 0 0 1 1 1 0 Late cornified envelope protein 6A family Septin PF00735.18 OAP61088.1 - 5.5e-107 357.2 0.0 1.3e-106 356.1 0.0 1.5 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 OAP61088.1 - 3.4e-05 23.9 0.0 8.7e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 OAP61088.1 - 0.0015 18.6 3.7 1.4 8.9 0.0 3.1 2 1 1 3 3 3 2 Dynamin family RsgA_GTPase PF03193.16 OAP61088.1 - 0.0024 17.8 2.2 0.009 15.9 0.1 2.7 3 1 0 3 3 3 1 RsgA GTPase GTP_EFTU PF00009.27 OAP61088.1 - 0.0039 16.8 0.1 0.31 10.6 0.0 2.4 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 OAP61088.1 - 0.1 12.9 0.8 0.19 12.0 0.1 2.0 2 1 0 2 2 2 0 AAA domain GBP_C PF02841.14 OAP61088.1 - 0.17 11.3 6.1 0.25 10.7 6.1 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain EB1 PF03271.17 OAP61088.1 - 0.48 10.7 3.2 5.6 7.3 1.1 2.6 2 0 0 2 2 2 0 EB1-like C-terminal motif TMPIT PF07851.13 OAP61088.1 - 2.3 7.4 3.5 3.5 6.8 3.5 1.2 1 0 0 1 1 1 0 TMPIT-like protein Pkinase PF00069.25 OAP61089.1 - 2.1e-51 174.8 0.0 2.7e-51 174.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP61089.1 - 1e-27 97.0 0.2 1.5e-26 93.3 0.2 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAP61089.1 - 0.0079 15.0 1.4 0.079 11.7 0.1 2.1 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 OAP61089.1 - 0.02 14.2 0.0 0.044 13.1 0.0 1.5 1 0 0 1 1 1 0 Kinase-like FTA2 PF13095.6 OAP61089.1 - 0.14 11.8 0.1 1.2 8.7 0.0 2.0 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 OAP61089.1 - 0.17 11.2 0.0 0.27 10.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Y_phosphatase3 PF13350.6 OAP61090.1 - 7.6e-47 160.2 0.0 1.2e-46 159.5 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 OAP61090.1 - 0.0026 17.4 0.0 0.0049 16.5 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 OAP61090.1 - 0.0038 16.8 0.0 0.0053 16.4 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 OAP61090.1 - 0.22 11.7 0.0 0.41 10.8 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate DLIC PF05783.11 OAP61091.1 - 6.1e-31 107.8 6.6 4.5e-30 104.9 0.0 3.1 3 0 0 3 3 3 2 Dynein light intermediate chain (DLIC) RRM_1 PF00076.22 OAP61092.1 - 4e-15 55.4 0.0 8.7e-15 54.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OAP61092.1 - 0.0094 15.5 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OAP61092.1 - 0.03 14.4 0.0 0.069 13.3 0.0 1.6 1 1 0 1 1 1 0 RNA recognition motif DUF4698 PF15769.5 OAP61092.1 - 0.095 11.7 3.1 0.15 11.1 3.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4698) DUF4407 PF14362.6 OAP61092.1 - 6.3 6.1 13.7 8.9 5.6 13.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AMP-binding PF00501.28 OAP61093.1 - 2.7e-97 326.0 0.0 3.2e-97 325.8 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAP61093.1 - 1.2e-19 71.0 0.1 2.8e-19 69.9 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Coiled-coil_56 PF09813.9 OAP61094.1 - 0.077 13.1 0.5 0.18 11.9 0.1 1.8 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 56 DUF2052 PF09747.9 OAP61095.1 - 8.6e-24 84.8 32.7 2.7e-15 57.0 9.1 4.1 3 1 0 4 4 4 2 Coiled-coil domain containing protein (DUF2052) ThiF PF00899.21 OAP61096.1 - 3.2e-32 111.8 0.0 4.6e-32 111.3 0.0 1.2 1 0 0 1 1 1 1 ThiF family MTD PF01993.18 OAP61096.1 - 0.092 12.1 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 methylene-5,6,7,8-tetrahydromethanopterin dehydrogenase Rit1_C PF17184.4 OAP61097.1 - 3e-75 253.2 0.0 4.2e-75 252.7 0.0 1.2 1 0 0 1 1 1 1 Rit1 N-terminal domain Init_tRNA_PT PF04179.12 OAP61097.1 - 3.5e-34 117.4 0.1 6.4e-34 116.6 0.1 1.5 1 0 0 1 1 1 1 Rit1 DUSP-like domain Aldo_ket_red PF00248.21 OAP61098.1 - 2.4e-47 161.6 0.0 1.4e-35 123.0 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family P3A PF08727.11 OAP61098.1 - 0.038 13.4 0.2 10 5.6 0.1 2.7 2 0 0 2 2 2 0 Poliovirus 3A protein like ALMT PF11744.8 OAP61098.1 - 0.11 11.3 0.1 0.16 10.8 0.1 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Rhabdo_M1 PF03342.13 OAP61098.1 - 0.17 11.2 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 Rhabdovirus M1 matrix protein (M1 polymerase-associated protein) Pro_CA PF00484.19 OAP61099.1 - 2.1e-10 41.1 1.0 1e-09 38.9 1.0 1.9 1 1 0 1 1 1 1 Carbonic anhydrase PLA2_B PF01735.18 OAP61102.1 - 3e-15 55.6 0.1 4.4e-07 28.7 0.0 2.2 2 0 0 2 2 2 2 Lysophospholipase catalytic domain Zn_clus PF00172.18 OAP61103.1 - 0.00058 19.9 12.9 0.0011 19.0 12.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cauli_DNA-bind PF03310.13 OAP61104.1 - 0.14 12.2 0.1 0.79 9.8 0.0 2.2 2 0 0 2 2 2 0 Caulimovirus DNA-binding protein vATP-synt_E PF01991.18 OAP61105.1 - 3.9e-64 215.7 12.5 4.6e-64 215.5 12.5 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit DUF3574 PF12098.8 OAP61105.1 - 0.2 11.5 1.7 0.3 10.9 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3574) Mg_trans_NIPA PF05653.14 OAP61106.1 - 2.2e-14 53.3 11.2 5.5e-08 32.3 2.0 2.0 2 0 0 2 2 2 2 Magnesium transporter NIPA PUNUT PF16913.5 OAP61106.1 - 1.3e-05 24.6 0.2 1.3e-05 24.6 0.2 2.1 2 0 0 2 2 2 1 Purine nucleobase transmembrane transport EamA PF00892.20 OAP61106.1 - 0.0051 17.0 2.9 0.0051 17.0 2.9 3.5 3 2 0 3 3 3 1 EamA-like transporter family CCDC106 PF15794.5 OAP61106.1 - 0.66 9.6 2.6 1 9.0 2.6 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 DUF5315 PF17242.2 OAP61107.1 - 4.9e-22 77.5 1.1 4.9e-22 77.5 1.1 1.9 2 0 0 2 2 2 1 Disordered region of unknown function (DUF5315) DUF4619 PF15398.6 OAP61107.1 - 0.021 14.4 1.1 0.038 13.5 1.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4619) Ribosom_S12_S23 PF00164.25 OAP61108.1 - 6.3e-51 170.8 0.7 8.2e-51 170.4 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 CTP_transf_like PF01467.26 OAP61109.1 - 6.3e-30 104.2 0.0 1.2e-29 103.3 0.0 1.5 1 0 0 1 1 1 1 Cytidylyltransferase-like TmoB PF06234.12 OAP61109.1 - 0.032 14.3 0.0 0.072 13.2 0.0 1.5 1 0 0 1 1 1 0 Toluene-4-monooxygenase system protein B (TmoB) Arena_RNA_pol PF06317.11 OAP61109.1 - 0.23 8.6 0.1 0.31 8.2 0.1 1.0 1 0 0 1 1 1 0 Arenavirus RNA polymerase PGA2 PF07543.12 OAP61109.1 - 0.83 9.6 4.0 0.26 11.3 0.8 1.8 2 0 0 2 2 2 0 Protein trafficking PGA2 PP2C PF00481.21 OAP61110.1 - 1.9e-80 270.3 0.0 4e-80 269.1 0.0 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C He_PIG PF05345.12 OAP61111.1 - 3e-11 43.3 6.7 0.0027 17.9 0.2 4.9 4 0 0 4 4 4 3 Putative Ig domain Peptidase_M7 PF02031.16 OAP61111.1 - 0.03 14.4 0.5 0.073 13.2 0.1 1.8 2 0 0 2 2 2 0 Streptomyces extracellular neutral proteinase (M7) family SUR7 PF06687.12 OAP61112.1 - 4.3e-34 118.0 6.6 5.1e-34 117.8 6.6 1.0 1 0 0 1 1 1 1 SUR7/PalI family DUF373 PF04123.13 OAP61112.1 - 0.18 11.2 7.1 0.29 10.5 7.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF373) Fig1 PF12351.8 OAP61112.1 - 1.5 8.8 17.1 0.032 14.2 10.4 1.6 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 Mannitol_dh_C PF08125.13 OAP61113.1 - 3.8e-44 151.0 0.0 6.1e-44 150.4 0.0 1.3 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.23 OAP61113.1 - 3.8e-21 75.8 0.6 2.1e-20 73.4 0.1 2.3 2 1 1 3 3 3 1 Mannitol dehydrogenase Rossmann domain 3HCDH_N PF02737.18 OAP61113.1 - 0.00056 19.9 1.7 0.011 15.6 0.0 3.0 4 0 0 4 4 4 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 OAP61113.1 - 0.006 16.2 0.8 0.012 15.2 0.3 1.8 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.16 OAP61113.1 - 0.011 15.4 0.0 0.31 10.7 0.0 2.3 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA NAD_binding_10 PF13460.6 OAP61113.1 - 0.016 15.1 1.0 11 5.9 0.3 3.2 2 1 0 2 2 2 0 NAD(P)H-binding NAD_Gly3P_dh_N PF01210.23 OAP61113.1 - 0.051 13.6 0.1 2.7 8.0 0.0 2.9 2 1 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DUF3425 PF11905.8 OAP61114.1 - 1.7e-13 50.7 0.1 3.2e-13 49.7 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) adh_short PF00106.25 OAP61115.1 - 9.6e-29 100.2 0.0 1.8e-28 99.3 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP61115.1 - 4e-23 82.2 0.0 7e-23 81.4 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP61115.1 - 0.00012 22.1 0.2 0.00024 21.1 0.2 1.5 1 0 0 1 1 1 1 KR domain Methyltransf_25 PF13649.6 OAP61115.1 - 0.021 15.5 0.1 0.046 14.4 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain HATPase_c PF02518.26 OAP61115.1 - 0.024 15.1 0.0 0.071 13.6 0.0 1.7 1 1 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ECH_1 PF00378.20 OAP61116.1 - 4e-47 160.6 0.0 6.4e-47 160.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAP61116.1 - 2.6e-27 96.2 0.6 4.2e-24 85.6 0.8 2.1 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase PGPGW PF09656.10 OAP61116.1 - 0.023 14.2 0.1 0.052 13.1 0.1 1.6 1 0 0 1 1 1 0 Putative transmembrane protein (PGPGW) SRF-TF PF00319.18 OAP61117.1 - 3.4e-21 74.5 0.1 4.7e-21 74.0 0.1 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) adh_short PF00106.25 OAP61118.1 - 1.7e-08 34.2 0.0 8.3e-07 28.7 0.0 2.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP61118.1 - 0.0087 15.6 0.0 0.026 14.1 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Tetraspanin PF00335.20 OAP61119.1 - 6.1e-05 22.8 11.3 0.00027 20.7 12.0 1.7 1 1 0 1 1 1 1 Tetraspanin family Fungal_trans_2 PF11951.8 OAP61120.1 - 8.4e-08 31.4 3.6 1.1e-07 31.0 3.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP61120.1 - 0.016 15.3 2.1 0.035 14.2 2.1 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DbpA PF03880.15 OAP61121.1 - 0.0042 17.0 0.0 0.011 15.8 0.0 1.6 1 0 0 1 1 1 1 DbpA RNA binding domain Peptidase_S49_N PF08496.10 OAP61122.1 - 0.0061 16.6 5.3 0.0061 16.6 5.3 2.0 2 0 0 2 2 2 1 Peptidase family S49 N-terminal zf-C3HC4_3 PF13920.6 OAP61122.1 - 0.26 11.2 5.0 1.5 8.8 2.6 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) U1snRNP70_N PF12220.8 OAP61122.1 - 1.7 9.4 9.7 2.6 8.7 3.2 3.0 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal CENP-F_N PF10481.9 OAP61123.1 - 0.0036 17.0 12.3 0.0049 16.6 12.3 1.1 1 0 0 1 1 1 1 Cenp-F N-terminal domain HIP1_clath_bdg PF16515.5 OAP61123.1 - 0.027 15.0 9.8 0.29 11.8 2.8 2.5 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 GreA_GreB_N PF03449.15 OAP61123.1 - 0.029 14.5 4.1 0.029 14.5 4.1 2.1 2 0 0 2 2 2 0 Transcription elongation factor, N-terminal DUF1640 PF07798.11 OAP61123.1 - 0.061 13.4 8.3 0.13 12.3 1.3 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1640) Cnn_1N PF07989.11 OAP61123.1 - 0.086 13.0 3.4 0.19 11.9 1.2 2.1 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 SlyX PF04102.12 OAP61123.1 - 0.13 12.8 5.2 4 8.1 2.0 2.5 2 0 0 2 2 2 0 SlyX DegS PF05384.11 OAP61123.1 - 0.39 10.2 9.8 0.083 12.4 5.4 1.9 2 0 0 2 2 2 0 Sensor protein DegS DUF4140 PF13600.6 OAP61123.1 - 0.7 10.4 10.2 1 9.9 4.3 2.6 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) FlaC_arch PF05377.11 OAP61123.1 - 0.72 10.3 4.6 0.57 10.6 0.4 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DivIC PF04977.15 OAP61123.1 - 1 9.2 11.5 0.88 9.4 7.3 2.3 2 0 0 2 2 2 0 Septum formation initiator Tmemb_cc2 PF10267.9 OAP61123.1 - 1.1 8.3 10.8 1.6 7.8 10.8 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein HALZ PF02183.18 OAP61123.1 - 1.3 9.3 6.6 0.26 11.5 1.7 2.0 2 0 0 2 2 2 0 Homeobox associated leucine zipper Csm1_N PF18504.1 OAP61123.1 - 1.7 9.1 7.6 1.9 8.9 3.1 2.4 2 0 0 2 2 2 0 Csm1 N-terminal domain CLZ PF16526.5 OAP61123.1 - 4 7.9 7.6 10 6.6 0.6 2.3 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF2046 PF09755.9 OAP61123.1 - 5.8 6.0 14.5 0.058 12.6 0.7 2.6 3 1 0 3 3 3 0 Uncharacterized conserved protein H4 (DUF2046) APG6_N PF17675.1 OAP61123.1 - 6 7.4 10.7 0.65 10.5 3.2 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region Spc24 PF08286.11 OAP61123.1 - 6.7 7.0 6.2 26 5.1 3.0 2.2 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 ATG16 PF08614.11 OAP61123.1 - 8.5 6.5 23.5 24 5.1 16.9 2.7 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) AIM5 PF17050.5 OAP61124.1 - 3.4e-19 69.4 1.1 7.5e-19 68.3 1.1 1.6 1 0 0 1 1 1 1 Altered inheritance of mitochondria 5 RapA_C PF12137.8 OAP61124.1 - 0.0075 15.3 0.4 0.2 10.7 0.5 1.9 1 1 1 2 2 2 1 RNA polymerase recycling family C-terminal YtxH PF12732.7 OAP61124.1 - 0.01 16.3 2.5 0.01 16.3 2.5 2.7 2 1 0 3 3 3 0 YtxH-like protein Apolipoprotein PF01442.18 OAP61124.1 - 0.015 15.2 3.2 0.035 14.0 3.3 1.6 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain MRP-L46 PF11788.8 OAP61124.1 - 0.05 14.3 1.1 0.079 13.7 1.1 1.3 1 0 0 1 1 1 0 39S mitochondrial ribosomal protein L46 RNase_J_C PF17770.1 OAP61124.1 - 0.074 14.1 2.4 0.4 11.8 0.1 2.2 1 1 1 2 2 2 0 Ribonuclease J C-terminal domain Mt_ATP-synt_D PF05873.12 OAP61124.1 - 0.24 11.2 2.6 0.39 10.6 2.6 1.4 1 1 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) Beta-lactamase PF00144.24 OAP61125.1 - 0.031 13.5 0.0 0.034 13.4 0.0 1.2 1 0 0 1 1 1 0 Beta-lactamase Beta-lactamase PF00144.24 OAP61126.1 - 1.5e-05 24.4 0.0 1.5e-05 24.4 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase UPF0270 PF06794.12 OAP61126.1 - 0.1 12.7 0.0 0.15 12.1 0.0 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0270) Arrestin_N PF00339.29 OAP61127.1 - 0.048 13.7 0.0 0.16 12.0 0.0 1.9 2 0 0 2 2 2 0 Arrestin (or S-antigen), N-terminal domain Rgp1 PF08737.10 OAP61127.1 - 0.21 10.7 0.0 0.42 9.7 0.0 1.4 1 0 0 1 1 1 0 Rgp1 SH3_1 PF00018.28 OAP61128.1 - 3.2e-13 49.1 0.1 1.1e-12 47.3 0.1 2.0 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 OAP61128.1 - 1.4e-12 47.1 0.0 2.9e-11 42.9 0.0 2.4 2 0 0 2 2 2 1 Variant SH3 domain G-alpha PF00503.20 OAP61128.1 - 8.1e-12 45.0 0.0 2.4e-11 43.4 0.0 1.6 2 0 0 2 2 2 1 G-protein alpha subunit SH3_9 PF14604.6 OAP61128.1 - 2.9e-10 39.8 0.0 6.2e-10 38.8 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain RP-C PF03428.13 OAP61128.1 - 0.045 13.4 1.8 0.2 11.3 0.0 2.2 2 0 0 2 2 2 0 Replication protein C N-terminal domain Glyco_hydro_106 PF17132.4 OAP61128.1 - 0.13 10.6 0.0 0.17 10.1 0.0 1.1 1 0 0 1 1 1 0 alpha-L-rhamnosidase MinC_N PF05209.13 OAP61128.1 - 0.17 11.8 0.0 0.37 10.8 0.0 1.5 1 0 0 1 1 1 0 Septum formation inhibitor MinC, N-terminal domain HisKA_3 PF07730.13 OAP61128.1 - 0.7 10.5 4.0 0.78 10.3 1.0 2.3 2 0 0 2 2 2 0 Histidine kinase DUF3176 PF11374.8 OAP61129.1 - 5.5e-35 119.8 0.7 1.5e-34 118.4 0.2 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF3176) DUF3341 PF11821.8 OAP61129.1 - 0.29 10.8 0.9 5.6 6.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3341) TMEM43 PF07787.12 OAP61129.1 - 0.41 10.0 1.3 0.75 9.1 1.3 1.4 1 0 0 1 1 1 0 Transmembrane protein 43 AMP-binding PF00501.28 OAP61130.1 - 1.2e-71 241.5 0.1 1.6e-71 241.2 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAP61130.1 - 3.2e-16 60.0 0.2 1.5e-15 57.9 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Ribosomal_L17 PF01196.19 OAP61131.1 - 1.3e-29 103.0 0.0 2e-29 102.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L17 IF-2B PF01008.17 OAP61132.1 - 6e-44 150.3 0.0 5.1e-23 81.7 0.0 2.1 1 1 1 2 2 2 2 Initiation factor 2 subunit family NIF PF03031.18 OAP61133.1 - 4.5e-58 195.5 0.0 6.4e-58 194.9 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Yos9_DD PF17880.1 OAP61133.1 - 0.13 12.3 0.0 0.23 11.6 0.0 1.3 1 0 0 1 1 1 0 Yos9 dimerzation domain EamA PF00892.20 OAP61134.1 - 1.1e-12 48.3 25.0 6e-07 29.7 8.9 3.2 3 0 0 3 3 3 3 EamA-like transporter family SUZ PF12752.7 OAP61135.1 - 2e-14 54.1 0.7 2e-14 54.1 0.7 5.6 5 0 0 5 5 5 1 SUZ domain R3H PF01424.22 OAP61135.1 - 8.7e-06 25.6 0.0 2.1e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 R3H domain cwf18 PF08315.12 OAP61136.1 - 3.1e-43 147.7 4.8 3.1e-43 147.7 4.8 2.0 2 0 0 2 2 2 1 cwf18 pre-mRNA splicing factor PPR_2 PF13041.6 OAP61137.1 - 3.3e-08 33.6 0.0 0.015 15.5 0.0 4.0 3 1 1 4 4 4 3 PPR repeat family PPR_long PF17177.4 OAP61137.1 - 3.6e-06 26.5 0.1 0.00024 20.6 0.0 2.9 3 0 0 3 3 3 1 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 OAP61137.1 - 6.3e-05 23.0 2.6 0.29 11.5 0.0 4.6 4 1 0 4 4 4 1 PPR repeat PPR_3 PF13812.6 OAP61137.1 - 0.076 13.1 0.0 3.5 7.8 0.0 3.1 2 1 1 3 3 3 0 Pentatricopeptide repeat domain C1_2 PF03107.16 OAP61138.1 - 0.04 14.2 0.1 0.085 13.2 0.1 1.5 1 0 0 1 1 1 0 C1 domain TFIID-18kDa PF02269.16 OAP61139.1 - 3.7e-17 62.1 0.0 8.4e-16 57.8 0.1 2.2 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit MitMem_reg PF13012.6 OAP61140.1 - 3.1e-19 69.5 0.4 5.2e-19 68.7 0.4 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 OAP61140.1 - 1e-17 64.2 0.0 1.6e-17 63.5 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease UPF0172 PF03665.13 OAP61140.1 - 7.7e-05 22.8 0.0 0.00022 21.3 0.0 1.7 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0172) BTB PF00651.31 OAP61141.1 - 1.2e-23 83.5 0.0 1.2e-11 44.8 0.1 2.9 3 0 0 3 3 3 2 BTB/POZ domain Ank PF00023.30 OAP61141.1 - 5.3e-08 33.0 0.1 0.0014 19.0 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 OAP61141.1 - 7.3e-08 32.9 0.1 1.6e-07 31.8 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OAP61141.1 - 1.2e-07 31.9 0.0 4.5e-07 30.0 0.0 2.1 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 OAP61141.1 - 4.5e-07 30.3 0.1 1.3e-06 28.9 0.1 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAP61141.1 - 9e-05 22.6 0.3 0.093 13.3 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeat DUF3342 PF11822.8 OAP61141.1 - 0.017 15.3 0.0 0.051 13.8 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3342) DEAD PF00270.29 OAP61142.1 - 2e-36 125.4 0.0 3.3e-36 124.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAP61142.1 - 4.8e-25 88.1 0.0 1.4e-23 83.3 0.1 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAP61142.1 - 5.1e-07 29.8 0.0 9.7e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 OAP61142.1 - 0.0038 16.6 0.0 0.025 13.9 0.0 2.0 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit BORCS6 PF10157.9 OAP61143.1 - 1.6e-05 25.2 0.1 2.4e-05 24.6 0.1 1.3 1 0 0 1 1 1 1 BLOC-1-related complex sub-unit 6 EzrA PF06160.12 OAP61143.1 - 9.5e-05 20.8 0.1 0.00013 20.4 0.1 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA MAD PF05557.13 OAP61143.1 - 0.0034 15.8 1.1 0.0047 15.4 1.1 1.1 1 0 0 1 1 1 1 Mitotic checkpoint protein DUF1664 PF07889.12 OAP61143.1 - 0.0066 16.5 2.7 0.015 15.4 2.6 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1664) AIP3 PF03915.13 OAP61143.1 - 0.0077 15.4 0.5 0.01 15.0 0.5 1.1 1 0 0 1 1 1 1 Actin interacting protein 3 DUF4200 PF13863.6 OAP61143.1 - 0.0091 16.4 1.3 0.015 15.7 1.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4200) BLOC1_2 PF10046.9 OAP61143.1 - 0.012 15.8 3.5 0.093 13.0 0.7 2.4 2 1 1 3 3 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CK2S PF15011.6 OAP61143.1 - 0.013 15.3 0.6 0.18 11.7 0.2 2.2 1 1 0 2 2 2 0 Casein Kinase 2 substrate Fib_alpha PF08702.10 OAP61143.1 - 0.015 15.5 1.0 0.026 14.7 1.0 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DHR10 PF18595.1 OAP61143.1 - 0.017 15.2 3.7 0.053 13.6 3.6 1.9 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain HEPN_AbiU2 PF18734.1 OAP61143.1 - 0.017 14.6 0.3 0.025 14.1 0.3 1.2 1 0 0 1 1 1 0 AbiU2 BEN PF10523.9 OAP61143.1 - 0.019 15.2 0.1 0.14 12.4 0.0 2.1 2 0 0 2 2 2 0 BEN domain CLZ PF16526.5 OAP61143.1 - 0.019 15.3 1.4 3.9 7.9 0.8 2.6 2 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DASH_Dad2 PF08654.10 OAP61143.1 - 0.022 15.2 0.1 1.5 9.3 0.0 2.4 2 0 0 2 2 2 0 DASH complex subunit Dad2 HBM PF16591.5 OAP61143.1 - 0.024 14.1 1.2 0.075 12.4 0.4 1.9 1 1 1 2 2 2 0 Helical bimodular sensor domain DUF4407 PF14362.6 OAP61143.1 - 0.027 13.8 0.2 0.031 13.6 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Fzo_mitofusin PF04799.13 OAP61143.1 - 0.027 14.0 2.4 0.13 11.8 2.4 1.9 1 1 0 1 1 1 0 fzo-like conserved region DUF948 PF06103.11 OAP61143.1 - 0.034 14.4 0.2 0.091 13.0 0.2 1.8 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) BORCS7 PF16088.5 OAP61143.1 - 0.034 14.4 0.8 0.11 12.8 0.8 1.7 1 1 0 1 1 1 0 BLOC-1-related complex sub-unit 7 FadA PF09403.10 OAP61143.1 - 0.039 14.4 0.1 0.066 13.7 0.1 1.3 1 0 0 1 1 1 0 Adhesion protein FadA Vps53_N PF04100.12 OAP61143.1 - 0.044 12.8 1.1 0.067 12.2 1.1 1.2 1 0 0 1 1 1 0 Vps53-like, N-terminal DUF5082 PF16888.5 OAP61143.1 - 0.045 14.0 4.0 9.5 6.5 0.0 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) Dynamitin PF04912.14 OAP61143.1 - 0.049 13.0 2.5 0.094 12.0 0.9 1.8 1 1 1 2 2 2 0 Dynamitin FlaC_arch PF05377.11 OAP61143.1 - 0.057 13.8 3.1 0.43 11.0 1.0 2.6 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Spc7 PF08317.11 OAP61143.1 - 0.058 12.3 0.3 0.094 11.6 0.3 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein kleA_kleC PF17383.2 OAP61143.1 - 0.075 13.4 0.2 0.18 12.1 0.1 1.7 2 0 0 2 2 1 0 Uncharacterized KorC regulated protein A Occludin_ELL PF07303.13 OAP61143.1 - 0.085 13.6 0.2 0.3 11.8 0.2 1.8 1 1 1 2 2 2 0 Occludin homology domain Baculo_PEP_C PF04513.12 OAP61143.1 - 0.1 12.7 0.1 0.49 10.4 0.1 1.9 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Med9 PF07544.13 OAP61143.1 - 0.1 12.7 2.3 0.32 11.1 0.9 2.4 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Hrs_helical PF12210.8 OAP61143.1 - 0.14 12.7 3.8 0.93 10.1 0.7 2.4 2 1 1 3 3 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate BAR_2 PF10455.9 OAP61143.1 - 0.14 11.2 1.1 0.24 10.5 1.1 1.4 1 1 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking THOC7 PF05615.13 OAP61143.1 - 0.17 12.2 4.1 0.45 10.8 4.0 1.9 1 1 0 1 1 1 0 Tho complex subunit 7 Vps51 PF08700.11 OAP61143.1 - 0.21 11.7 1.6 7.2 6.8 0.8 2.9 2 1 0 2 2 2 0 Vps51/Vps67 DUF1515 PF07439.11 OAP61143.1 - 0.25 11.4 3.2 0.35 10.9 2.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1515) DASH_Duo1 PF08651.10 OAP61143.1 - 0.3 10.9 3.0 2.2 8.1 0.2 2.8 3 0 0 3 3 3 0 DASH complex subunit Duo1 Snapin_Pallidin PF14712.6 OAP61143.1 - 0.31 11.5 11.2 0.034 14.6 3.1 2.8 2 1 0 2 2 2 0 Snapin/Pallidin CorA PF01544.18 OAP61143.1 - 0.34 10.2 4.8 1.1 8.4 4.8 1.8 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF4164 PF13747.6 OAP61143.1 - 0.39 11.0 6.7 2 8.7 6.9 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) YkyA PF10368.9 OAP61143.1 - 0.44 10.2 3.1 0.81 9.3 3.2 1.4 1 1 0 1 1 1 0 Putative cell-wall binding lipoprotein HAUS4 PF14735.6 OAP61143.1 - 0.78 9.4 3.3 22 4.6 0.2 2.8 2 1 1 3 3 3 0 HAUS augmin-like complex subunit 4 Wbp11 PF09429.10 OAP61144.1 - 1.2e-20 73.6 16.3 1.2e-20 73.6 16.3 2.1 2 1 0 2 2 2 1 WW domain binding protein 11 DUF3040 PF11239.8 OAP61144.1 - 1.2 9.4 4.2 6.9 7.0 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) Pkinase PF00069.25 OAP61145.1 - 3.1e-55 187.4 0.3 1.3e-34 119.8 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAP61145.1 - 4e-35 121.3 0.0 4.8e-25 88.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 OAP61145.1 - 0.0045 16.4 0.0 0.018 14.4 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 OAP61145.1 - 0.077 11.8 0.0 0.19 10.5 0.0 1.6 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 OAP61145.1 - 0.11 12.4 0.9 2.3 8.1 0.0 2.5 2 1 0 3 3 3 0 Phosphotransferase enzyme family DUF3896 PF13035.6 OAP61145.1 - 0.16 12.2 1.3 0.6 10.3 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3896) zf-C2H2 PF00096.26 OAP61146.1 - 4.7e-08 33.1 13.5 6.5e-05 23.2 2.4 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OAP61146.1 - 3e-05 24.3 1.5 3e-05 24.3 1.5 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 OAP61146.1 - 0.00024 21.7 11.5 0.042 14.7 1.8 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 OAP61146.1 - 0.0015 18.9 1.3 0.013 15.9 0.2 2.3 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 OAP61146.1 - 0.0045 17.2 3.5 0.12 12.7 0.2 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 OAP61146.1 - 0.079 13.0 0.4 0.079 13.0 0.4 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 OAP61146.1 - 0.17 12.1 3.1 7.6 6.8 0.6 2.4 2 0 0 2 2 2 0 Zinc ribbon domain zf-MYST PF17772.1 OAP61146.1 - 0.4 10.3 8.1 3.1 7.5 1.8 2.4 2 0 0 2 2 2 0 MYST family zinc finger domain Zn_ribbon_SprT PF17283.2 OAP61146.1 - 2 8.4 10.8 0.13 12.2 4.7 2.0 2 0 0 2 2 2 0 SprT-like zinc ribbon domain MtrG PF04210.13 OAP61148.1 - 0.043 13.7 0.0 1.3 8.9 0.0 2.2 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G Herpes_heli_pri PF05774.11 OAP61148.1 - 0.12 12.6 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus helicase-primase complex component RNA_pol_3_Rpc31 PF11705.8 OAP61148.1 - 0.12 12.7 9.1 0.14 12.3 9.1 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 AC_N PF16214.5 OAP61148.1 - 2.9 6.9 5.6 3.4 6.7 5.6 1.1 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region Sugar_tr PF00083.24 OAP61149.1 - 2.1e-78 264.2 28.2 2.4e-78 264.0 28.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP61149.1 - 1.5e-26 93.2 32.0 3.8e-25 88.6 22.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PhyH PF05721.13 OAP61150.1 - 1.4e-16 61.4 0.1 1.8e-16 61.0 0.1 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 OAP61150.1 - 0.066 13.6 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase DIOX_N PF14226.6 OAP61150.1 - 0.088 13.6 0.0 11 6.9 0.0 2.9 3 0 0 3 3 3 0 non-haem dioxygenase in morphine synthesis N-terminal PPP4R2 PF09184.11 OAP61151.1 - 0.33 10.5 9.7 0.37 10.3 9.7 1.2 1 0 0 1 1 1 0 PPP4R2 NOA36 PF06524.12 OAP61151.1 - 1.6 7.9 13.0 2.4 7.4 13.0 1.3 1 0 0 1 1 1 0 NOA36 protein Hid1 PF12722.7 OAP61151.1 - 3.9 5.5 4.4 3.9 5.5 4.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SAPS PF04499.15 OAP61151.1 - 6 5.5 6.8 6.7 5.4 6.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SURF2 PF05477.11 OAP61151.1 - 9.2 5.9 12.5 13 5.4 12.5 1.1 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Pkinase PF00069.25 OAP61152.1 - 1.9e-32 112.7 0.0 2.8e-32 112.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP61152.1 - 2.6e-15 56.4 0.0 3.7e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Chromo PF00385.24 OAP61152.1 - 0.015 15.2 0.0 0.038 13.9 0.0 1.6 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain APH PF01636.23 OAP61152.1 - 0.095 12.6 0.0 0.44 10.4 0.0 2.0 1 1 0 1 1 1 0 Phosphotransferase enzyme family CorA PF01544.18 OAP61154.1 - 8.8e-17 61.3 0.0 2e-16 60.2 0.0 1.5 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein CK2S PF15011.6 OAP61154.1 - 0.0011 18.9 1.7 0.1 12.5 0.3 3.1 3 0 0 3 3 3 2 Casein Kinase 2 substrate UTP25 PF06862.12 OAP61155.1 - 3.8e-175 583.2 0.0 4.7e-175 582.9 0.0 1.1 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Hydrolase_6 PF13344.6 OAP61156.1 - 7.4e-23 80.6 0.0 1.5e-22 79.6 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OAP61156.1 - 1.5e-17 63.4 0.0 8.6e-17 61.0 0.0 2.3 1 1 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 OAP61156.1 - 0.006 16.9 0.0 5.3 7.3 0.0 2.9 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HTH_27 PF13463.6 OAP61156.1 - 0.19 12.3 0.0 0.57 10.7 0.0 1.8 2 0 0 2 2 2 0 Winged helix DNA-binding domain DUF3665 PF12427.8 OAP61156.1 - 0.28 10.9 1.9 0.54 10.0 1.9 1.4 1 0 0 1 1 1 0 Branched-chain amino acid aminotransferase Alpha-amylase PF00128.24 OAP61157.1 - 4.9e-19 69.1 2.7 6.8e-19 68.6 1.0 2.1 2 1 0 2 2 2 1 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.11 OAP61157.1 - 2.1e-13 50.6 0.0 3.5e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 OAP61157.1 - 4.9e-06 26.2 0.0 1e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 OAP61157.1 - 0.021 14.8 0.0 0.057 13.4 0.0 1.7 1 0 0 1 1 1 0 Glycosyltransferase Family 4 SMI1_KNR4 PF09346.10 OAP61158.1 - 8e-35 120.1 0.0 1.3e-34 119.4 0.0 1.4 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) SUKH_5 PF14567.6 OAP61158.1 - 0.14 11.9 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 SMI1-KNR4 cell-wall Bmt2 PF11968.8 OAP61159.1 - 2e-68 230.6 0.0 4.1e-67 226.3 0.0 2.4 2 1 0 2 2 2 1 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 Kin17_mid PF10357.9 OAP61160.1 - 1.1e-52 177.2 1.2 1.9e-52 176.5 1.2 1.4 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein zf-C2H2_jaz PF12171.8 OAP61160.1 - 0.00029 21.0 0.9 0.00059 20.0 0.9 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OAP61160.1 - 0.0012 19.1 2.2 0.0023 18.3 2.2 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 OAP61160.1 - 0.0034 17.7 2.6 0.013 15.8 0.2 2.3 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) DUF3236 PF11576.8 OAP61160.1 - 0.39 10.4 1.7 0.74 9.5 0.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3236) DUF2263 PF10021.9 OAP61161.1 - 4.2e-08 33.7 0.0 8.4e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Macro PF01661.21 OAP61161.1 - 0.075 13.1 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Macro domain DIOX_N PF14226.6 OAP61162.1 - 1.6e-19 70.8 0.1 3.3e-19 69.8 0.1 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OAP61162.1 - 5.9e-13 49.2 0.1 1.5e-12 47.9 0.0 1.7 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CorA PF01544.18 OAP61163.1 - 6.1e-47 160.3 0.0 9.6e-47 159.7 0.0 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein YmdB PF13277.6 OAP61163.1 - 0.15 11.3 0.2 0.24 10.7 0.2 1.2 1 0 0 1 1 1 0 YmdB-like protein zf-rbx1 PF12678.7 OAP61164.1 - 4.7e-25 87.6 12.7 7e-25 87.1 12.7 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 OAP61164.1 - 4.3e-17 62.0 10.0 5.7e-17 61.6 10.0 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 OAP61164.1 - 5.9e-06 26.5 15.2 0.0002 21.6 15.2 2.2 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 OAP61164.1 - 7.8e-05 22.4 3.4 7.8e-05 22.4 3.4 2.3 1 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAP61164.1 - 0.0016 18.2 11.5 0.023 14.5 11.5 2.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 OAP61164.1 - 0.11 12.6 8.4 0.49 10.6 8.6 1.8 1 1 1 2 2 2 0 FANCL C-terminal domain zf-C3HC4_3 PF13920.6 OAP61164.1 - 0.3 11.0 10.4 0.65 9.9 4.0 2.4 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAP61164.1 - 0.36 10.9 7.2 1.2 9.2 7.2 1.9 1 1 0 1 1 1 0 RING-type zinc-finger Zn_ribbon_17 PF17120.5 OAP61164.1 - 0.53 9.9 14.7 0.13 11.9 4.8 2.2 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 OAP61164.1 - 1.2 9.0 17.1 98 2.8 17.1 2.5 1 1 0 1 1 1 0 RING-like zinc finger PNRC PF15365.6 OAP61165.1 - 2.1e-08 33.8 6.4 2.1e-08 33.8 6.4 3.3 4 0 0 4 4 4 1 Proline-rich nuclear receptor coactivator motif G10 PF01125.17 OAP61166.1 - 5.5e-65 217.6 1.3 6.4e-65 217.4 1.3 1.0 1 0 0 1 1 1 1 G10 protein zf-Tim10_DDP PF02953.15 OAP61167.1 - 1.1e-21 76.2 1.9 1.5e-21 75.8 1.9 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Ribosomal_L23eN PF03939.13 OAP61168.1 - 5.7e-27 93.7 9.6 5.7e-27 93.7 9.6 1.8 2 0 0 2 2 2 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 OAP61168.1 - 3.6e-16 59.3 0.8 3.6e-16 59.3 0.8 1.6 2 0 0 2 2 2 1 Ribosomal protein L23 P2 PF07194.11 OAP61168.1 - 0.011 15.8 0.2 0.021 14.8 0.2 1.5 2 0 0 2 2 2 0 P2 response regulator binding domain DUF1323 PF07037.11 OAP61168.1 - 0.1 13.0 0.1 0.24 11.8 0.0 1.6 2 0 0 2 2 2 0 Putative transcription regulator (DUF1323) TusA PF01206.17 OAP61168.1 - 0.13 12.1 0.2 0.29 11.0 0.2 1.6 2 0 0 2 2 2 0 Sulfurtransferase TusA Thioredoxin PF00085.20 OAP61169.1 - 0.00041 20.3 0.0 0.00063 19.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin EamA PF00892.20 OAP61170.1 - 0.00027 21.1 9.1 0.00027 21.1 9.1 2.2 2 0 0 2 2 2 1 EamA-like transporter family KH_1 PF00013.29 OAP61171.1 - 4e-07 29.8 0.1 1.7e-06 27.7 0.0 2.0 2 0 0 2 2 2 1 KH domain PEHE PF15275.6 OAP61171.1 - 0.048 14.3 6.2 0.87 10.2 3.7 2.9 2 0 0 2 2 2 0 PEHE domain DUF2431 PF10354.9 OAP61172.1 - 6.7e-57 192.4 0.0 1.9e-56 191.0 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF2431) WD40 PF00400.32 OAP61173.1 - 6.1e-06 26.9 19.0 0.0016 19.2 0.5 6.0 6 0 0 6 6 6 3 WD domain, G-beta repeat FAD_binding_3 PF01494.19 OAP61174.1 - 9e-37 127.1 0.0 2.1e-36 125.9 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain Fungal_trans PF04082.18 OAP61174.1 - 4.9e-13 48.7 0.2 1e-12 47.7 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain UQ_con PF00179.26 OAP61175.1 - 3.5e-48 162.8 0.0 3.9e-48 162.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OAP61175.1 - 0.00075 19.2 0.0 0.001 18.8 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 OAP61175.1 - 0.016 15.1 0.1 0.03 14.2 0.1 1.5 1 1 0 1 1 1 0 UEV domain RWD PF05773.22 OAP61175.1 - 0.064 13.5 0.1 0.11 12.7 0.1 1.4 1 1 0 1 1 1 0 RWD domain Ribosomal_L24e PF01246.20 OAP61177.1 - 2.2e-27 95.1 0.3 2.2e-27 95.1 0.3 1.8 2 0 0 2 2 2 1 Ribosomal protein L24e DUF775 PF05603.12 OAP61177.1 - 0.12 11.9 1.7 0.15 11.5 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF775) DUF1770 PF08589.10 OAP61178.1 - 2.9e-21 76.3 6.1 4.9e-20 72.3 6.1 2.1 1 1 0 1 1 1 1 Fungal protein of unknown function (DUF1770) PfkB PF00294.24 OAP61179.1 - 1.7e-64 218.1 0.0 1.9e-64 217.8 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 OAP61179.1 - 0.013 14.9 0.0 0.025 14.0 0.0 1.4 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase EST1_DNA_bind PF10373.9 OAP61180.1 - 4.4e-46 157.6 0.9 2.3e-45 155.2 0.2 2.2 2 1 0 2 2 2 1 Est1 DNA/RNA binding domain EST1 PF10374.9 OAP61180.1 - 4.9e-22 79.0 1.1 1.7e-21 77.3 1.1 2.0 1 0 0 1 1 1 1 Telomerase activating protein Est1 TPR_17 PF13431.6 OAP61180.1 - 0.025 14.9 0.5 0.1 13.0 0.5 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.28 OAP61180.1 - 0.034 14.0 0.5 5.5 7.0 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 OAP61180.1 - 0.078 13.8 0.3 0.45 11.5 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TFIIA PF03153.13 OAP61180.1 - 1.7 8.5 11.6 3.3 7.6 11.6 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ribosomal_L5_C PF00673.21 OAP61181.1 - 2.7e-28 98.0 0.0 4.2e-28 97.4 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 OAP61181.1 - 5.3e-07 29.9 0.0 9.5e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L5 Beta-lactamase PF00144.24 OAP61182.1 - 3.1e-46 158.1 0.0 9.8e-46 156.5 0.0 1.6 1 1 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.20 OAP61182.1 - 0.014 14.9 0.0 0.019 14.4 0.0 1.2 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase UCH_1 PF13423.6 OAP61183.1 - 1.9e-12 47.4 0.0 1.5e-08 34.6 0.0 2.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase NDUFA12 PF05071.16 OAP61184.1 - 2.4e-32 111.6 1.3 2.9e-32 111.3 1.3 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 LTV PF04180.14 OAP61185.1 - 3.2e-113 379.3 8.4 3.7e-113 379.2 8.4 1.0 1 0 0 1 1 1 1 Low temperature viability protein Glyco_hydro_92N PF17678.1 OAP61185.1 - 0.045 13.6 0.0 0.069 13.0 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 92 N-terminal domain MMR_HSR1 PF01926.23 OAP61186.1 - 1.9e-17 63.3 0.5 5.2e-15 55.5 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OAP61186.1 - 1.8e-08 34.5 0.4 0.00061 19.7 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 OAP61186.1 - 1e-07 31.6 0.3 1.2e-05 24.9 0.1 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B AIG1 PF04548.16 OAP61186.1 - 0.0089 15.4 0.1 0.0089 15.4 0.1 2.2 3 0 0 3 3 3 1 AIG1 family cobW PF02492.19 OAP61186.1 - 0.043 13.4 0.8 0.16 11.6 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.23 OAP61186.1 - 0.048 13.7 0.3 0.048 13.7 0.3 3.5 4 1 0 4 4 4 0 Dynamin family MeaB PF03308.16 OAP61186.1 - 0.14 11.1 0.1 0.54 9.2 0.0 1.9 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF3365 PF11845.8 OAP61186.1 - 1.1 9.6 2.9 1.6 9.0 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3365) SUIM_assoc PF16619.5 OAP61186.1 - 4.5 7.4 8.2 1.4 9.0 2.0 2.7 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 MFS_1 PF07690.16 OAP61187.1 - 1e-38 133.2 50.0 2.2e-38 132.1 41.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 OAP61187.1 - 0.0016 16.8 6.7 0.069 11.4 2.8 2.5 1 1 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family zf-C2H2_jaz PF12171.8 OAP61189.1 - 2e-09 37.5 2.6 0.0012 19.1 1.0 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OAP61189.1 - 5.2e-08 33.0 2.6 0.00092 19.5 0.9 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 OAP61189.1 - 9.6e-05 22.9 2.9 0.035 14.9 0.1 4.3 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2 PF00096.26 OAP61189.1 - 0.00086 19.6 5.0 0.012 16.0 0.3 3.8 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 OAP61189.1 - 0.0014 19.0 3.9 0.28 11.5 0.6 2.6 2 1 1 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 OAP61189.1 - 0.0019 18.1 1.5 0.054 13.5 0.1 2.8 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_11 PF16622.5 OAP61189.1 - 0.0061 16.3 0.3 0.0061 16.3 0.3 3.6 4 0 0 4 4 4 2 zinc-finger C2H2-type zf-C2HC_2 PF13913.6 OAP61189.1 - 0.03 14.2 8.5 0.32 11.0 0.7 3.4 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-H2C2_2 PF13465.6 OAP61189.1 - 0.87 10.1 0.1 0.87 10.1 0.1 3.7 4 0 0 4 4 4 0 Zinc-finger double domain zf-LYAR PF08790.11 OAP61189.1 - 1.2 9.2 7.7 1.3 9.0 0.1 2.9 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger Mu-like_Com PF10122.9 OAP61189.1 - 6.5 6.3 8.2 7 6.2 0.5 2.9 3 0 0 3 3 3 0 Mu-like prophage protein Com IBR PF01485.21 OAP61190.1 - 4.5e-11 42.8 25.1 6.2e-07 29.6 8.6 3.8 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain zf-RING_UBOX PF13445.6 OAP61190.1 - 0.0073 16.3 11.1 0.0073 16.3 11.1 4.6 4 1 0 4 4 4 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OAP61190.1 - 0.013 15.4 12.3 0.013 15.4 12.3 4.2 3 2 1 4 4 4 0 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.22 OAP61190.1 - 0.018 14.9 0.0 3.7 7.4 0.0 3.2 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DNA_topoisoIV PF00521.20 OAP61190.1 - 0.2 10.5 0.0 0.31 9.9 0.0 1.2 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A Abhydrolase_3 PF07859.13 OAP61191.1 - 7.7e-52 176.2 0.0 9.6e-52 175.9 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 OAP61191.1 - 9.6e-05 21.4 0.6 0.0016 17.4 0.6 2.1 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 OAP61191.1 - 0.00012 21.6 0.0 0.0074 15.8 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family DUF1899 PF08953.11 OAP61191.1 - 0.086 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1899) AXE1 PF05448.12 OAP61191.1 - 0.098 11.3 0.0 0.15 10.7 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) DLH PF01738.18 OAP61191.1 - 0.11 12.0 0.1 1.3 8.5 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family Say1_Mug180 PF10340.9 OAP61191.1 - 0.15 10.9 0.0 0.33 9.8 0.0 1.6 1 1 0 1 1 1 0 Steryl acetyl hydrolase Sad1_UNC PF07738.13 OAP61192.1 - 5.1e-32 110.7 0.1 9.9e-32 109.7 0.1 1.5 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal PLDc_2 PF13091.6 OAP61194.1 - 7.1e-13 48.6 0.0 1.7e-06 27.9 0.0 2.8 3 0 0 3 3 3 2 PLD-like domain PLDc PF00614.22 OAP61194.1 - 5.1e-06 26.4 1.3 0.36 11.1 0.1 3.5 2 1 0 2 2 2 2 Phospholipase D Active site motif Pkinase PF00069.25 OAP61195.1 - 2.1e-50 171.6 0.0 3e-50 171.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP61195.1 - 2.7e-29 102.2 0.0 3.9e-29 101.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAP61195.1 - 2.3e-14 53.4 0.0 2.9e-10 40.0 0.0 3.1 2 1 1 3 3 3 3 Kinase-like Kdo PF06293.14 OAP61195.1 - 0.0036 16.7 0.0 0.0073 15.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Acyl-CoA_dh_1 PF00441.24 OAP61196.1 - 6.3e-28 97.9 0.8 1.2e-27 97.0 0.8 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 OAP61196.1 - 5.9e-19 68.1 0.0 1.1e-18 67.2 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 OAP61196.1 - 1.1e-14 55.0 0.1 2.4e-14 53.9 0.0 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 OAP61196.1 - 2.7e-12 47.1 0.5 5e-12 46.2 0.5 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain SAC3_GANP PF03399.16 OAP61197.1 - 5e-93 311.7 0.0 8e-93 311.0 0.0 1.3 1 0 0 1 1 1 1 SAC3/GANP family PAM2 PF07145.15 OAP61197.1 - 0.16 11.7 0.5 0.51 10.2 0.5 1.9 1 0 0 1 1 1 0 Ataxin-2 C-terminal region SDA1 PF05285.12 OAP61197.1 - 0.43 9.9 26.3 2.1 7.7 26.3 2.2 1 0 0 1 1 1 0 SDA1 DUF2841 PF11001.8 OAP61198.1 - 8e-33 113.1 1.5 1.3e-32 112.4 1.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) ABC_membrane PF00664.23 OAP61199.1 - 4.7e-78 262.6 21.9 7.7e-39 134.0 6.7 2.7 2 1 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 OAP61199.1 - 2.7e-51 173.7 0.3 3.6e-30 105.3 0.1 2.8 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.19 OAP61199.1 - 2.6e-10 40.1 7.0 0.00094 18.7 0.1 4.7 3 2 1 5 5 5 3 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 OAP61199.1 - 4.4e-06 26.8 2.5 0.039 14.0 0.0 3.0 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_23 PF13476.6 OAP61199.1 - 2.1e-05 25.1 0.3 0.0015 19.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 OAP61199.1 - 2.4e-05 24.3 0.1 0.015 15.1 0.0 3.0 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 OAP61199.1 - 2.5e-05 24.2 0.1 0.015 15.2 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 OAP61199.1 - 0.00012 21.8 1.6 0.066 13.0 0.0 3.3 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 OAP61199.1 - 0.0002 21.8 0.4 0.21 12.0 0.2 2.6 2 0 0 2 2 2 2 AAA ATPase domain Dynamin_N PF00350.23 OAP61199.1 - 0.0017 18.4 0.3 0.28 11.2 0.0 2.6 2 0 0 2 2 2 1 Dynamin family AAA_27 PF13514.6 OAP61199.1 - 0.0067 16.0 0.1 0.03 13.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 OAP61199.1 - 0.0097 16.3 0.0 0.58 10.6 0.0 2.8 2 0 0 2 2 2 1 RNA helicase DUF87 PF01935.17 OAP61199.1 - 0.017 15.2 1.1 1.4 9.0 0.1 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_30 PF13604.6 OAP61199.1 - 0.036 13.8 0.7 1.1 9.0 0.0 2.8 2 1 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 OAP61199.1 - 0.045 13.5 0.7 2.6 7.7 0.0 2.8 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_15 PF13175.6 OAP61199.1 - 0.072 12.8 2.5 0.2 11.3 0.1 2.2 2 0 0 2 2 2 0 AAA ATPase domain Roc PF08477.13 OAP61199.1 - 0.083 13.1 0.1 14 5.9 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 OAP61199.1 - 0.16 12.3 5.4 4.3 7.6 0.1 3.5 2 1 0 2 2 2 0 AAA domain GTP_EFTU PF00009.27 OAP61199.1 - 0.18 11.3 0.1 8.8 5.8 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain DUF4748 PF15932.5 OAP61199.1 - 0.56 10.0 3.7 2.9 7.7 3.7 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4748) Peptidase_C2 PF00648.21 OAP61200.1 - 9.4e-66 221.8 6.3 2.4e-64 217.2 6.3 2.2 1 1 0 1 1 1 1 Calpain family cysteine protease C2-C2_1 PF11618.8 OAP61200.1 - 0.13 12.4 0.1 0.22 11.6 0.1 1.3 1 0 0 1 1 1 0 First C2 domain of RPGR-interacting protein 1 RabGAP-TBC PF00566.18 OAP61201.1 - 1.9e-47 161.7 0.0 3.2e-47 161.0 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_6 PF13405.6 OAP61201.1 - 0.00059 19.6 0.9 0.077 13.0 0.4 3.5 2 0 0 2 2 2 1 EF-hand domain GRAM PF02893.20 OAP61201.1 - 0.04 13.8 0.0 0.095 12.6 0.0 1.6 1 1 0 1 1 1 0 GRAM domain EF-hand_1 PF00036.32 OAP61201.1 - 0.093 12.3 0.6 1.3 8.7 1.1 2.7 2 0 0 2 2 2 0 EF hand CNH PF00780.22 OAP61202.1 - 1.1e-65 222.1 0.0 1.6e-65 221.5 0.0 1.2 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.20 OAP61202.1 - 7.7e-31 107.7 0.0 2.7e-30 106.0 0.0 1.9 2 0 0 2 2 2 1 RhoGEF domain PH_5 PF15405.6 OAP61202.1 - 2.3e-12 47.2 0.0 3.3e-10 40.2 0.0 2.9 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 OAP61202.1 - 1.5e-06 28.7 0.0 0.00028 21.3 0.0 2.8 2 0 0 2 2 2 1 PH domain FAD_binding_3 PF01494.19 OAP61204.1 - 1e-50 173.0 0.0 1.4e-50 172.6 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAP61204.1 - 1.7e-05 24.6 0.0 0.077 12.6 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAP61204.1 - 9.9e-05 22.5 0.2 0.00039 20.6 0.2 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 OAP61204.1 - 0.00015 21.2 0.1 0.0069 15.7 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAP61204.1 - 0.001 17.9 0.0 0.012 14.4 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 OAP61204.1 - 0.0041 16.5 0.0 0.012 14.9 0.0 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAP61204.1 - 0.0042 16.3 0.0 0.012 14.8 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAP61204.1 - 0.0044 16.3 0.0 0.0088 15.3 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 OAP61204.1 - 0.0067 17.0 0.1 0.083 13.5 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 OAP61204.1 - 0.014 14.7 0.1 0.44 9.8 0.0 2.4 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 OAP61204.1 - 0.016 14.3 0.6 0.049 12.7 0.6 1.8 1 1 0 1 1 1 0 Lycopene cyclase protein FAD_binding_2 PF00890.24 OAP61204.1 - 0.016 14.3 0.4 0.062 12.4 0.4 1.7 1 1 1 2 2 2 0 FAD binding domain NAD_binding_9 PF13454.6 OAP61204.1 - 0.025 14.6 0.4 0.4 10.7 0.0 2.8 4 0 0 4 4 4 0 FAD-NAD(P)-binding ApbA PF02558.16 OAP61204.1 - 0.17 11.5 0.1 0.3 10.7 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA MFS_1 PF07690.16 OAP61205.1 - 1.5e-42 145.8 38.2 4.8e-36 124.4 13.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAP61205.1 - 2.6e-10 39.8 8.1 8.7e-09 34.7 0.2 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.7 OAP61205.1 - 0.0017 17.3 5.4 0.0017 17.3 5.4 2.8 1 1 1 2 2 2 1 MFS_1 like family MFS_2 PF13347.6 OAP61205.1 - 0.006 15.2 0.6 0.006 15.2 0.6 2.7 2 1 0 2 2 2 1 MFS/sugar transport protein Folate_carrier PF01770.18 OAP61205.1 - 0.16 10.7 0.0 0.25 10.0 0.0 1.2 1 0 0 1 1 1 0 Reduced folate carrier 5_nucleotid_C PF02872.18 OAP61207.1 - 1.3e-35 123.0 0.0 2.3e-35 122.2 0.0 1.4 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 OAP61207.1 - 2.9e-05 24.7 0.0 4.7e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Aminotran_1_2 PF00155.21 OAP61208.1 - 2.1e-84 283.8 0.0 2.7e-84 283.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 OAP61208.1 - 3.6e-06 25.8 0.0 5.7e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 OAP61208.1 - 6.9e-06 25.6 0.1 1.3e-05 24.7 0.1 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 OAP61208.1 - 8e-06 25.0 0.0 1.4e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 OAP61208.1 - 0.0058 15.9 0.1 0.012 14.9 0.1 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase DUF3405 PF11885.8 OAP61208.1 - 0.072 11.7 0.3 0.1 11.2 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3405) RNA_pol_I_A49 PF06870.12 OAP61209.1 - 1.4e-73 248.0 0.1 1.7e-73 247.7 0.1 1.1 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor OxoDH_E1alpha_N PF12573.8 OAP61209.1 - 0.023 14.4 0.2 0.065 13.0 0.2 1.8 1 0 0 1 1 1 0 2-oxoisovalerate dehydrogenase E1 alpha subunit N terminal Haem_oxygenas_2 PF14518.6 OAP61211.1 - 1.3e-34 119.5 0.0 2.7e-34 118.5 0.0 1.6 1 0 0 1 1 1 1 Iron-containing redox enzyme 2OG-FeII_Oxy PF03171.20 OAP61212.1 - 1.7e-09 38.1 0.0 4.6e-09 36.7 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 OAP61212.1 - 4.1e-08 34.0 0.0 6.6e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal tRNA-synt_1b PF00579.25 OAP61214.1 - 9.3e-33 113.8 0.0 1.6e-32 113.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Ub-Mut7C PF14451.6 OAP61214.1 - 0.17 11.7 0.0 0.6 10.0 0.0 1.9 2 0 0 2 2 2 0 Mut7-C ubiquitin Pyridox_ox_2 PF12900.7 OAP61215.1 - 4.3e-39 133.7 0.0 5.7e-39 133.3 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase FMN_bind_2 PF04299.12 OAP61215.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Putative FMN-binding domain Peptidase_M20 PF01546.28 OAP61216.1 - 5e-19 68.8 0.0 1e-18 67.8 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 OAP61216.1 - 1.2e-13 50.9 0.0 3e-13 49.6 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Pkinase PF00069.25 OAP61217.1 - 6.1e-57 193.0 0.0 1.7e-50 171.9 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAP61217.1 - 3.7e-24 85.4 0.0 1.5e-21 76.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase FHA PF00498.26 OAP61217.1 - 3.1e-10 40.3 0.0 7.7e-10 39.0 0.0 1.7 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.6 OAP61217.1 - 2.3e-06 27.1 0.0 3.7e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OAP61217.1 - 4.6e-05 22.4 0.0 0.00011 21.1 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Yop-YscD_cpl PF16697.5 OAP61217.1 - 0.00024 21.4 0.0 0.00064 20.0 0.0 1.8 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Kdo PF06293.14 OAP61217.1 - 0.015 14.6 0.0 0.033 13.5 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family AA_permease_2 PF13520.6 OAP61218.1 - 1.7e-56 191.9 51.7 2.1e-56 191.6 51.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAP61218.1 - 1.8e-21 76.3 42.9 2.4e-21 75.9 42.9 1.2 1 0 0 1 1 1 1 Amino acid permease ECSCR PF15820.5 OAP61218.1 - 0.028 14.2 0.2 0.15 11.9 0.0 2.3 2 0 0 2 2 2 0 Endothelial cell-specific chemotaxis regulator TssN PF17555.2 OAP61218.1 - 3.6 6.9 8.6 4.9 6.4 6.9 2.1 1 1 1 2 2 2 0 Type VI secretion system, TssN SNF2_N PF00176.23 OAP61219.1 - 5.1e-65 219.5 1.5 8.6e-65 218.7 1.5 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OAP61219.1 - 1.6e-19 70.3 0.0 3.7e-19 69.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAP61219.1 - 1.1e-07 32.0 0.0 2.9e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 OAP61219.1 - 0.0005 19.9 0.0 0.0021 17.8 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 OAP61219.1 - 0.0032 16.7 0.0 0.029 13.5 0.0 2.3 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 Paf1 PF03985.13 OAP61219.1 - 0.019 14.0 4.7 0.57 9.1 1.2 2.1 2 0 0 2 2 2 0 Paf1 HTH_17 PF12728.7 OAP61219.1 - 0.099 12.8 0.4 7.2 6.9 0.1 2.7 2 0 0 2 2 2 0 Helix-turn-helix domain baeRF_family12 PF18856.1 OAP61219.1 - 0.53 10.9 4.5 0.39 11.3 0.1 2.3 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 12 Cas_CT1975 PF09344.10 OAP61219.1 - 0.84 9.0 5.7 1.4 8.3 5.7 1.2 1 0 0 1 1 1 0 CT1975-like protein DBINO PF13892.6 OAP61220.1 - 2.4e-48 163.9 19.4 2.4e-48 163.9 19.4 3.5 3 1 0 3 3 3 1 DNA-binding domain Fe_hyd_lg_C PF02906.14 OAP61220.1 - 1.7 8.2 8.6 0.043 13.5 1.6 1.8 2 0 0 2 2 2 0 Iron only hydrogenase large subunit, C-terminal domain Rotamase_3 PF13616.6 OAP61221.1 - 7.7e-16 58.7 0.1 1.5e-15 57.7 0.1 1.5 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 OAP61221.1 - 2.4e-14 54.1 0.1 5.5e-14 52.9 0.0 1.6 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 OAP61221.1 - 0.0011 19.8 0.0 0.0014 19.5 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain DUF3970 PF13113.6 OAP61221.1 - 0.13 12.5 0.0 0.27 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3970) CYSTM PF12734.7 OAP61223.1 - 0.18 12.1 50.9 2.6 8.4 46.4 3.7 2 1 0 2 2 2 0 Cysteine-rich TM module stress tolerance Abhydrolase_1 PF00561.20 OAP61224.1 - 6e-17 62.1 0.0 6.6e-15 55.4 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAP61224.1 - 1.1e-13 52.3 0.1 6.8e-13 49.7 0.1 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAP61224.1 - 1.6e-06 27.6 0.0 5.2e-05 22.6 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 EHN PF06441.12 OAP61224.1 - 0.038 14.4 0.8 0.096 13.1 0.1 2.1 3 0 0 3 3 3 0 Epoxide hydrolase N terminus Ferric_reduct PF01794.19 OAP61226.1 - 1.8e-17 63.6 9.0 1.8e-17 63.6 9.0 2.0 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 OAP61226.1 - 1.5e-11 44.6 0.0 3.9e-11 43.3 0.0 1.6 2 0 0 2 2 2 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 OAP61226.1 - 0.035 14.8 0.0 3.5 8.3 0.0 2.5 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain FAD_binding_8 PF08022.12 OAP61226.1 - 0.054 13.6 0.0 0.13 12.4 0.0 1.7 1 0 0 1 1 1 0 FAD-binding domain Glyco_transf_8 PF01501.20 OAP61227.1 - 5.1e-22 78.7 0.1 1.4e-21 77.2 0.1 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 8 Prok-E2_E PF14462.6 OAP61227.1 - 0.08 12.8 0.2 0.27 11.0 0.2 1.9 1 0 0 1 1 1 0 Prokaryotic E2 family E Zip PF02535.22 OAP61227.1 - 8.1 5.6 4.9 11 5.1 4.9 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter SNF2_N PF00176.23 OAP61228.1 - 3.5e-68 229.9 0.0 5e-68 229.4 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.11 OAP61228.1 - 1e-16 60.6 0.0 2e-16 59.7 0.0 1.5 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.31 OAP61228.1 - 4.1e-14 52.9 0.1 1.4e-13 51.1 0.0 2.0 2 0 0 2 2 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.6 OAP61228.1 - 5.6e-10 38.9 13.7 1.2e-09 37.8 13.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OAP61228.1 - 1.8e-08 34.1 11.9 1.8e-08 34.1 11.9 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAP61228.1 - 1.2e-07 31.9 13.5 1.2e-07 31.9 13.5 2.0 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 OAP61228.1 - 1.3e-06 28.2 14.1 1.3e-06 28.2 14.1 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAP61228.1 - 1.3e-06 28.3 10.4 3.6e-06 26.9 10.4 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 OAP61228.1 - 5.9e-06 26.3 12.6 1.2e-05 25.4 12.6 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 OAP61228.1 - 1.8e-05 24.6 12.4 4e-05 23.5 12.4 1.6 1 0 0 1 1 1 1 zinc-RING finger domain DEAD PF00270.29 OAP61228.1 - 9.4e-05 22.2 0.0 0.0002 21.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Prok-RING_4 PF14447.6 OAP61228.1 - 0.00012 21.9 12.3 0.00025 20.8 12.3 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 OAP61228.1 - 0.00014 22.1 9.8 0.00031 21.0 9.8 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_10 PF16685.5 OAP61228.1 - 0.007 16.5 9.4 0.017 15.2 9.4 1.6 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-ANAPC11 PF12861.7 OAP61228.1 - 0.015 15.3 3.6 0.04 14.0 3.6 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger HDA2-3 PF11496.8 OAP61228.1 - 0.017 14.3 0.9 0.3 10.2 0.0 3.3 4 1 0 4 4 4 0 Class II histone deacetylase complex subunits 2 and 3 zf-RING_4 PF14570.6 OAP61228.1 - 0.055 13.3 9.5 0.11 12.3 9.5 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-P11 PF03854.14 OAP61228.1 - 0.076 12.7 9.6 0.15 11.7 7.6 2.2 2 0 0 2 2 2 0 P-11 zinc finger zf-Nse PF11789.8 OAP61228.1 - 0.24 11.2 9.6 0.19 11.6 7.7 1.9 2 0 0 2 2 1 0 Zinc-finger of the MIZ type in Nse subunit K1377 PF15352.6 OAP61228.1 - 0.43 8.8 2.9 0.66 8.2 2.9 1.2 1 0 0 1 1 1 0 Susceptibility to monomelic amyotrophy zf-RING_11 PF17123.5 OAP61228.1 - 1.3 8.8 7.6 4.7 7.1 7.6 2.1 1 0 0 1 1 1 0 RING-like zinc finger RIX1 PF08167.12 OAP61229.1 - 9.9e-46 155.8 3.9 2.6e-45 154.5 1.9 2.4 3 0 0 3 3 3 1 rRNA processing/ribosome biogenesis RTP1_C1 PF10363.9 OAP61229.1 - 0.014 15.6 0.0 1.4 9.1 0.0 3.0 3 1 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 TPR_8 PF13181.6 OAP61230.1 - 1.9e-05 24.5 7.9 0.77 10.1 0.0 7.1 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_19 PF14559.6 OAP61230.1 - 2e-05 25.0 8.0 0.63 10.6 0.0 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 OAP61230.1 - 4.1e-05 23.4 7.0 3.1 8.1 0.1 6.7 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.6 OAP61230.1 - 0.002 18.8 11.7 0.78 10.7 0.1 5.6 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_6 PF13174.6 OAP61230.1 - 0.13 13.0 7.7 5.2 7.9 0.0 5.0 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_17 PF13431.6 OAP61230.1 - 0.4 11.2 2.1 8.9 7.0 0.0 3.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 OAP61230.1 - 0.69 9.8 5.8 36 4.4 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 OAP61230.1 - 1.4 9.3 11.5 3.4 8.0 0.1 5.8 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_16 PF13432.6 OAP61230.1 - 1.8 9.3 3.8 51 4.6 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 OAP61230.1 - 2.2 8.5 7.9 94 3.4 0.0 5.6 7 0 0 7 7 7 0 Tetratricopeptide repeat Asp PF00026.23 OAP61231.1 - 7.9e-73 245.6 5.2 1.1e-72 245.1 5.2 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OAP61231.1 - 7.5e-13 49.1 4.0 1.8e-10 41.3 2.6 3.4 2 2 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 OAP61231.1 - 6.2e-07 30.0 1.5 0.0056 17.3 0.4 3.6 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 OAP61231.1 - 0.00046 20.7 0.5 0.31 11.6 0.0 3.4 3 1 0 3 3 3 2 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 OAP61231.1 - 0.021 14.6 0.0 0.087 12.6 0.0 2.1 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal Abhydrolase_1 PF00561.20 OAP61232.1 - 3e-23 82.8 0.2 1.5e-22 80.4 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 OAP61232.1 - 3.3e-22 77.8 0.1 6.6e-22 76.9 0.1 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Hydrolase_4 PF12146.8 OAP61232.1 - 7.6e-06 25.4 0.0 0.00073 18.9 0.0 2.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 FSH1 PF03959.13 OAP61232.1 - 0.00052 19.8 0.0 0.23 11.1 0.0 2.2 2 0 0 2 2 2 2 Serine hydrolase (FSH1) Aa_trans PF01490.18 OAP61232.1 - 0.013 14.2 0.0 0.023 13.4 0.0 1.3 1 0 0 1 1 1 0 Transmembrane amino acid transporter protein Ku PF02735.16 OAP61233.1 - 3e-43 147.9 0.0 9e-43 146.4 0.0 1.8 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 OAP61233.1 - 2.1e-34 119.2 0.0 3e-34 118.7 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 OAP61233.1 - 1.1e-25 90.1 0.3 3.6e-25 88.5 0.3 1.9 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm SAP PF02037.27 OAP61233.1 - 1.1e-10 41.0 0.0 2.1e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 SAP domain FRG1 PF06229.12 OAP61233.1 - 0.1 12.3 0.1 0.9 9.2 0.0 2.1 2 0 0 2 2 2 0 FRG1-like domain Ferrochelatase PF00762.19 OAP61234.1 - 1.4e-99 333.1 0.0 1.7e-99 332.9 0.0 1.1 1 0 0 1 1 1 1 Ferrochelatase adh_short_C2 PF13561.6 OAP61235.1 - 8.7e-51 172.7 1.2 9e-49 166.1 0.2 2.0 1 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP61235.1 - 1.7e-45 154.9 1.4 2.3e-38 131.6 0.1 2.2 1 1 1 2 2 2 2 short chain dehydrogenase KR PF08659.10 OAP61235.1 - 2.6e-09 37.3 3.2 1e-08 35.3 3.2 1.7 1 1 0 1 1 1 1 KR domain LtrA PF06772.11 OAP61237.1 - 2.1e-22 79.8 15.6 5.3e-22 78.5 15.5 1.6 1 1 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) MFS_1 PF07690.16 OAP61238.1 - 2.5e-28 99.1 47.2 4.2e-27 95.0 27.7 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.25 OAP61239.1 - 8.6e-68 228.6 0.9 1.1e-66 225.0 0.9 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP61239.1 - 5.3e-51 173.4 1.2 5.3e-51 173.4 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase PBD PF00786.28 OAP61239.1 - 4.2e-24 84.7 1.1 1e-23 83.4 0.1 2.3 2 0 0 2 2 2 1 P21-Rho-binding domain PH_11 PF15413.6 OAP61239.1 - 4.2e-10 40.0 0.1 1.3e-09 38.4 0.1 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain Haspin_kinase PF12330.8 OAP61239.1 - 5e-06 25.7 0.0 1.1e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 OAP61239.1 - 1.2e-05 24.8 0.0 2.4e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OAP61239.1 - 6.4e-05 21.9 0.0 6.4e-05 21.9 0.0 2.0 2 1 0 2 2 1 1 Fungal protein kinase PH PF00169.29 OAP61239.1 - 6.4e-05 23.4 0.1 0.00017 22.1 0.1 1.7 1 0 0 1 1 1 1 PH domain KIND PF16474.5 OAP61239.1 - 0.026 14.4 0.0 0.063 13.2 0.0 1.6 1 0 0 1 1 1 0 Kinase non-catalytic C-lobe domain Seadorna_VP7 PF07387.11 OAP61239.1 - 0.034 13.2 0.1 0.058 12.4 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 U79_P34 PF03064.16 OAP61239.1 - 0.12 11.7 3.9 0.25 10.7 3.9 1.4 1 0 0 1 1 1 0 HSV U79 / HCMV P34 APH PF01636.23 OAP61239.1 - 0.23 11.3 4.5 0.69 9.8 0.3 2.9 2 1 1 3 3 3 0 Phosphotransferase enzyme family WD40 PF00400.32 OAP61240.1 - 2.8e-18 65.9 3.9 0.0062 17.4 0.0 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAP61240.1 - 1.2e-06 28.8 0.1 0.00089 19.5 0.0 3.4 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OAP61240.1 - 0.0052 15.8 0.8 2.4 7.0 0.1 3.5 2 2 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Peptidase_C25_C PF03785.14 OAP61240.1 - 0.048 13.5 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Peptidase family C25, C terminal ig-like domain adh_short_C2 PF13561.6 OAP61241.1 - 2e-30 106.1 0.0 2.5e-30 105.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP61241.1 - 4.8e-26 91.4 0.0 6.4e-26 91.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAP61241.1 - 3.7e-08 33.5 0.0 5.6e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_7 PF13241.6 OAP61241.1 - 0.0067 16.9 0.0 0.048 14.1 0.0 2.1 2 0 0 2 2 2 1 Putative NAD(P)-binding THF_DHG_CYH_C PF02882.19 OAP61241.1 - 0.11 11.9 0.1 0.67 9.3 0.0 2.2 3 0 0 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.21 OAP61241.1 - 0.17 11.4 0.0 0.33 10.4 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family FSH1 PF03959.13 OAP61242.1 - 2.1e-24 86.4 0.0 2.8e-24 85.9 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 OAP61242.1 - 0.0025 18.4 0.0 0.0059 17.2 0.0 1.4 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAP61242.1 - 0.036 13.7 0.0 0.91 9.1 0.0 2.4 3 0 0 3 3 3 0 alpha/beta hydrolase fold FlgD_ig PF13860.6 OAP61243.1 - 0.029 14.2 1.4 0.095 12.6 0.0 2.6 3 0 0 3 3 3 0 FlgD Ig-like domain SecE PF00584.20 OAP61243.1 - 0.031 14.2 0.5 0.062 13.2 0.5 1.4 1 0 0 1 1 1 0 SecE/Sec61-gamma subunits of protein translocation complex PIG-X PF08320.12 OAP61244.1 - 1.1e-63 215.0 0.0 1.5e-63 214.5 0.0 1.2 1 0 0 1 1 1 1 PIG-X / PBN1 EST1_DNA_bind PF10373.9 OAP61247.1 - 3.3e-09 36.6 0.0 8.3e-09 35.3 0.0 1.6 2 0 0 2 2 2 1 Est1 DNA/RNA binding domain ALMS_motif PF15309.6 OAP61247.1 - 0.045 14.2 0.6 0.094 13.2 0.6 1.5 1 0 0 1 1 1 0 ALMS motif Mid1 PF12929.7 OAP61248.1 - 9.8e-159 529.1 1.8 1.2e-158 528.8 1.8 1.1 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.22 OAP61248.1 - 0.0033 18.0 7.4 0.27 11.9 3.6 2.7 2 1 0 2 2 2 2 Fz domain Es2 PF09751.9 OAP61249.1 - 1.7e-107 360.9 12.5 2e-107 360.6 12.5 1.1 1 0 0 1 1 1 1 Nuclear protein Es2 SF3b1 PF08920.10 OAP61249.1 - 0.28 11.7 3.6 0.7 10.4 0.1 2.7 2 1 0 2 2 2 0 Splicing factor 3B subunit 1 TPR_2 PF07719.17 OAP61250.1 - 6.9e-17 60.1 29.3 0.015 15.3 0.3 13.0 13 0 0 13 13 13 5 Tetratricopeptide repeat TPR_19 PF14559.6 OAP61250.1 - 2.9e-12 46.9 33.4 0.0017 18.8 0.3 10.0 8 2 1 10 10 9 5 Tetratricopeptide repeat TPR_8 PF13181.6 OAP61250.1 - 4.3e-09 35.9 19.6 0.58 10.5 0.1 10.3 12 0 0 12 12 12 3 Tetratricopeptide repeat TPR_14 PF13428.6 OAP61250.1 - 5.7e-09 36.1 42.5 0.33 11.9 0.6 13.4 11 5 4 15 15 13 4 Tetratricopeptide repeat TPR_1 PF00515.28 OAP61250.1 - 5.8e-09 35.4 28.3 0.0034 17.2 0.3 11.5 14 0 0 14 14 14 2 Tetratricopeptide repeat TPR_12 PF13424.6 OAP61250.1 - 2.6e-06 27.6 31.0 0.63 10.4 0.5 10.4 10 1 2 12 12 12 4 Tetratricopeptide repeat TPR_16 PF13432.6 OAP61250.1 - 1.6e-05 25.5 41.2 0.016 15.8 1.1 8.2 9 1 1 10 10 8 4 Tetratricopeptide repeat ANAPC3 PF12895.7 OAP61250.1 - 5.4e-05 23.3 9.9 0.023 14.9 0.5 5.5 5 0 0 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 OAP61250.1 - 0.00011 21.8 13.7 5.2 6.8 0.5 7.8 7 0 0 7 7 7 1 TPR repeat TPR_17 PF13431.6 OAP61250.1 - 0.0011 19.2 25.8 1.5 9.4 0.2 9.9 12 0 0 12 12 10 1 Tetratricopeptide repeat TPR_7 PF13176.6 OAP61250.1 - 0.036 14.1 20.8 0.4 10.8 0.4 7.7 9 0 0 9 9 8 0 Tetratricopeptide repeat CEND1 PF15677.5 OAP61250.1 - 0.54 10.8 11.3 2 9.0 11.3 2.0 1 0 0 1 1 1 0 Cell cycle exit and neuronal differentiation protein 1 TPR_6 PF13174.6 OAP61250.1 - 2.1 9.1 30.7 5.2 7.9 0.1 11.3 13 0 0 13 13 11 0 Tetratricopeptide repeat TPR_3 PF07720.12 OAP61250.1 - 2.3 8.3 12.7 10 6.2 0.2 5.2 5 0 0 5 5 4 0 Tetratricopeptide repeat RSN1_7TM PF02714.15 OAP61251.1 - 4e-88 295.3 16.2 6.4e-88 294.6 16.2 1.3 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_ext PF12621.8 OAP61251.1 - 5.7e-26 90.5 0.1 2e-25 88.8 0.1 2.0 2 0 0 2 2 2 1 Extracellular tail, of 10TM putative phosphate transporter PHM7_cyt PF14703.6 OAP61251.1 - 4e-24 85.8 0.4 7.2e-24 85.0 0.4 1.4 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 OAP61251.1 - 0.012 15.4 0.5 0.051 13.3 0.5 2.2 1 0 0 1 1 1 0 Late exocytosis, associated with Golgi transport RRM_1 PF00076.22 OAP61251.1 - 0.017 14.9 0.0 0.036 13.9 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Fungal_trans_2 PF11951.8 OAP61252.1 - 4.8e-10 38.8 2.9 6.1e-09 35.2 0.2 2.6 3 0 0 3 3 3 2 Fungal specific transcription factor domain Sugar_tr PF00083.24 OAP61253.1 - 6.7e-52 176.9 5.9 7.9e-52 176.6 5.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP61253.1 - 2.5e-07 30.0 24.9 1.7e-05 23.9 19.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAP61254.1 - 1.4e-34 119.7 4.1 1.4e-34 119.7 4.1 1.4 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP61254.1 - 4.3e-11 42.4 11.9 4.3e-11 42.4 11.9 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 OAP61254.1 - 0.00084 19.1 1.8 0.0013 18.5 1.8 1.3 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 TRI12 PF06609.13 OAP61254.1 - 0.0015 17.1 1.1 0.0018 16.7 1.1 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_5 PF05631.14 OAP61254.1 - 0.0031 16.5 0.4 0.0034 16.4 0.4 1.2 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_2 PF13347.6 OAP61254.1 - 0.011 14.3 1.7 0.02 13.4 1.7 1.4 1 0 0 1 1 1 0 MFS/sugar transport protein PTR2 PF00854.21 OAP61254.1 - 0.045 12.6 0.3 0.045 12.6 0.3 1.8 2 0 0 2 2 2 0 POT family p450 PF00067.22 OAP61255.1 - 3.6e-63 213.9 0.0 4.6e-63 213.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Tcf25 PF04910.14 OAP61255.1 - 0.086 11.9 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Transcriptional repressor TCF25 DUF325 PF03804.13 OAP61255.1 - 0.12 12.4 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 Viral proteins of unknown function Dioxygenase_C PF00775.21 OAP61257.1 - 7e-33 113.6 0.0 9.3e-33 113.2 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 OAP61257.1 - 2e-28 98.1 0.0 3.6e-28 97.2 0.0 1.4 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 OAP61257.1 - 0.001 19.3 0.0 0.003 17.8 0.0 1.8 1 1 0 1 1 1 1 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 OAP61257.1 - 0.13 12.3 0.0 2.6 8.1 0.0 2.3 2 0 0 2 2 2 0 CarboxypepD_reg-like domain ET PF01684.16 OAP61259.1 - 0.015 15.6 0.6 0.015 15.6 0.6 2.6 3 0 0 3 3 3 0 ET module DUF3433 PF11915.8 OAP61260.1 - 1.3e-11 44.7 0.1 4e-11 43.2 0.1 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3433) Zn_clus PF00172.18 OAP61261.1 - 0.0003 20.8 13.3 0.00061 19.9 13.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 OAP61261.1 - 0.00082 18.3 2.1 0.0013 17.6 1.9 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Abhydrolase_6 PF12697.7 OAP61262.1 - 1.8e-08 35.3 0.5 2.9e-08 34.6 0.5 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAP61262.1 - 9e-06 25.5 0.3 3.3e-05 23.7 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAP61262.1 - 0.00032 20.0 0.2 0.0015 17.8 0.2 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 LIDHydrolase PF10230.9 OAP61262.1 - 0.021 14.4 0.0 0.035 13.7 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Peptidase_S9 PF00326.21 OAP61262.1 - 0.051 13.1 0.0 5.3 6.5 0.0 2.4 2 0 0 2 2 2 0 Prolyl oligopeptidase family HCV_NS4a PF01006.20 OAP61263.1 - 0.29 10.9 1.3 0.49 10.2 1.3 1.4 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein NS4a Ysc84 PF04366.12 OAP61264.1 - 4.7e-38 129.8 0.6 7.6e-38 129.2 0.6 1.3 1 0 0 1 1 1 1 Las17-binding protein actin regulator HET PF06985.11 OAP61265.1 - 3e-15 56.8 0.0 4.1e-15 56.4 0.0 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF5449 PF17528.2 OAP61265.1 - 0.12 12.2 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5449) Hydrophobin_2 PF06766.11 OAP61268.1 - 2e-25 88.5 10.6 2e-25 88.5 10.6 1.6 2 0 0 2 2 2 1 Fungal hydrophobin Hydrolase PF00702.26 OAP61269.1 - 1.3e-26 94.2 0.8 9.1e-21 75.1 0.1 2.8 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 OAP61269.1 - 1.4e-26 93.2 0.1 6.1e-26 91.0 0.1 2.2 1 1 0 1 1 1 1 E1-E2 ATPase HMA PF00403.26 OAP61269.1 - 1.6e-07 31.7 0.1 6e-07 29.8 0.0 2.0 2 0 0 2 2 2 1 Heavy-metal-associated domain MFS_1 PF07690.16 OAP61271.1 - 2.3e-27 95.8 23.3 2.3e-27 95.8 23.3 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Wzz PF02706.15 OAP61271.1 - 0.095 13.0 1.5 1 9.7 0.0 3.1 3 0 0 3 3 3 0 Chain length determinant protein Herpes_LMP1 PF05297.11 OAP61271.1 - 0.15 11.2 1.0 0.44 9.7 1.0 1.8 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) FAD_binding_3 PF01494.19 OAP61272.1 - 6.9e-15 55.1 0.0 2.2e-14 53.5 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 OAP61272.1 - 5.4e-09 35.6 0.3 1.2e-08 34.5 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 OAP61272.1 - 6.4e-09 35.4 0.1 0.00019 20.8 0.0 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAP61272.1 - 6.2e-07 29.3 4.5 0.0002 21.1 0.3 2.6 2 1 0 3 3 3 2 FAD dependent oxidoreductase HI0933_like PF03486.14 OAP61272.1 - 6.3e-07 28.4 0.1 1.4e-05 24.0 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 OAP61272.1 - 6.3e-06 25.8 0.0 1.2e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAP61272.1 - 9.8e-06 25.7 0.0 5.8e-05 23.2 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 OAP61272.1 - 0.00014 21.1 0.0 0.00021 20.5 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.27 OAP61272.1 - 0.00099 19.6 0.2 0.055 14.0 0.1 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAP61272.1 - 0.0037 16.6 0.2 0.011 15.0 0.3 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OAP61272.1 - 0.027 13.5 0.2 0.13 11.2 0.1 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 OAP61272.1 - 0.039 13.2 0.0 0.067 12.5 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 OAP61272.1 - 0.097 11.9 0.1 0.18 11.0 0.1 1.3 1 0 0 1 1 1 0 Thi4 family p450 PF00067.22 OAP61273.1 - 4.6e-75 253.1 0.0 5.6e-75 252.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 bVLRF1 PF18826.1 OAP61274.1 - 4.4e-60 201.9 0.0 4.4e-60 201.9 0.0 1.9 2 0 0 2 2 2 1 bacteroidetes VLRF1 release factor Ank_5 PF13857.6 OAP61274.1 - 8.5e-08 32.3 0.1 2.1e-07 31.1 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) zf-C2H2_jaz PF12171.8 OAP61274.1 - 0.037 14.3 0.1 0.074 13.4 0.1 1.5 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Ank PF00023.30 OAP61274.1 - 0.28 11.7 0.9 0.72 10.4 0.9 1.7 1 0 0 1 1 1 0 Ankyrin repeat PARP PF00644.20 OAP61275.1 - 1.4e-54 184.6 0.0 4.9e-54 182.9 0.0 1.8 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 OAP61275.1 - 3.2e-41 140.6 0.3 5.5e-41 139.9 0.3 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 OAP61275.1 - 1.2e-19 70.1 0.2 2.4e-19 69.1 0.2 1.5 1 0 0 1 1 1 1 WGR domain BRCT_2 PF16589.5 OAP61275.1 - 1.7e-05 25.1 0.1 3.7e-05 24.0 0.1 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 OAP61275.1 - 0.066 13.2 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 twin BRCT domain BRCT PF00533.26 OAP61275.1 - 0.069 13.5 0.0 0.15 12.4 0.0 1.6 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain DUF3751 PF12571.8 OAP61275.1 - 0.12 12.5 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 Phage tail-collar fibre protein Macoilin PF09726.9 OAP61276.1 - 7.6 5.0 8.1 9 4.7 8.1 1.1 1 0 0 1 1 1 0 Macoilin family DER1 PF04511.15 OAP61277.1 - 7.1e-25 88.0 3.9 8e-25 87.9 3.9 1.0 1 0 0 1 1 1 1 Der1-like family DKCLD PF08068.12 OAP61278.1 - 3.5e-28 97.5 1.1 2.5e-24 85.1 0.2 3.6 3 0 0 3 3 3 2 DKCLD (NUC011) domain TruB_N PF01509.18 OAP61278.1 - 3.4e-23 82.7 0.1 3e-20 73.1 0.1 3.3 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 OAP61278.1 - 1.7e-22 79.3 0.7 3.2e-22 78.4 0.7 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain PUA PF01472.20 OAP61278.1 - 3.8e-21 74.8 1.5 7.3e-21 73.9 1.5 1.5 1 0 0 1 1 1 1 PUA domain UPF0113 PF03657.13 OAP61278.1 - 0.0088 16.3 0.0 0.022 15.0 0.0 1.7 1 0 0 1 1 1 1 UPF0113 PUA domain RNA_polI_A34 PF08208.11 OAP61278.1 - 0.89 9.6 21.4 1.6 8.8 21.4 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 RR_TM4-6 PF06459.12 OAP61278.1 - 3.3 7.4 12.9 4.3 7.1 12.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Pkinase PF00069.25 OAP61279.1 - 5.1e-48 163.7 0.0 8.1e-48 163.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP61279.1 - 1.4e-26 93.4 0.0 1.9e-26 92.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OAP61279.1 - 0.009 15.4 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OAP61279.1 - 0.023 14.0 0.0 0.046 13.0 0.0 1.5 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 OAP61279.1 - 0.067 13.1 0.6 2.4 8.0 0.0 2.9 2 1 1 3 3 3 0 Phosphotransferase enzyme family BAR PF03114.18 OAP61281.1 - 5.9e-59 199.6 2.5 8.1e-59 199.2 2.5 1.1 1 0 0 1 1 1 1 BAR domain CP12 PF02672.15 OAP61281.1 - 0.028 15.1 0.1 0.13 13.0 0.0 2.3 2 0 0 2 2 2 0 CP12 domain FliD_N PF02465.18 OAP61281.1 - 0.11 13.2 2.3 4.5 8.0 0.6 2.4 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Arfaptin PF06456.13 OAP61281.1 - 0.5 9.9 4.2 2.4 7.7 4.2 2.0 1 1 0 1 1 1 0 Arfaptin-like domain ETF PF01012.21 OAP61282.1 - 1.1e-45 155.8 0.8 1.3e-45 155.5 0.8 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Skp1 PF01466.19 OAP61283.1 - 2.9e-28 97.7 0.5 5e-28 97.0 0.5 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 OAP61283.1 - 1.1e-23 83.1 0.6 2.6e-23 82.0 0.3 1.7 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain RT_RNaseH_2 PF17919.1 OAP61285.1 - 7e-22 77.4 0.0 1.5e-21 76.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAP61285.1 - 2e-17 63.4 0.0 5e-17 62.1 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Glyco_trans_2_3 PF13632.6 OAP61286.1 - 8.4e-47 159.6 6.0 8.4e-47 159.6 6.0 2.4 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 OAP61286.1 - 0.00023 21.0 0.0 0.00066 19.5 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 OAP61286.1 - 0.00046 20.1 0.1 0.00091 19.2 0.1 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 OAP61286.1 - 0.0099 15.4 0.1 0.035 13.6 0.1 1.8 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glyco_transf_22 PF03901.17 OAP61287.1 - 1.9e-61 208.6 23.7 2.6e-61 208.1 23.7 1.2 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Glyco_hydro_16 PF00722.21 OAP61287.1 - 2.2e-15 56.6 2.9 2.2e-15 56.6 2.9 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 UBA PF00627.31 OAP61288.1 - 5.7e-24 83.6 1.5 5.6e-14 51.7 0.1 2.6 2 0 0 2 2 2 2 UBA/TS-N domain XPC-binding PF09280.11 OAP61288.1 - 3.6e-22 77.8 12.1 6e-22 77.1 12.1 1.4 1 0 0 1 1 1 1 XPC-binding domain ubiquitin PF00240.23 OAP61288.1 - 1.2e-20 73.0 0.1 1.9e-20 72.4 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 OAP61288.1 - 1e-06 28.5 0.2 1.6e-06 27.8 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 OAP61288.1 - 0.0033 17.5 0.0 0.0062 16.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 OAP61288.1 - 0.0045 17.5 0.0 0.0078 16.8 0.0 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain UBA_3 PF09288.10 OAP61288.1 - 0.029 14.2 0.0 2.3 8.1 0.0 2.4 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain Phasin_2 PF09361.10 OAP61288.1 - 0.052 13.8 0.7 0.1 12.9 0.7 1.5 1 0 0 1 1 1 0 Phasin protein HTH_15 PF12324.8 OAP61288.1 - 0.11 12.5 0.1 0.26 11.3 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of alkylmercury lyase Ubiquitin_2 PF14560.6 OAP61288.1 - 0.11 13.0 0.0 0.26 11.8 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-like domain MCM_N PF14551.6 OAP61288.1 - 0.12 13.0 0.0 0.25 12.0 0.0 1.5 1 0 0 1 1 1 0 MCM N-terminal domain DUF1421 PF07223.11 OAP61288.1 - 0.17 11.7 0.0 0.65 9.9 0.0 1.9 2 0 0 2 2 2 0 UBA-like domain (DUF1421) Med6 PF04934.14 OAP61289.1 - 2.1e-33 114.9 0.0 3.1e-33 114.4 0.0 1.2 1 0 0 1 1 1 1 MED6 mediator sub complex component SnAPC_2_like PF11035.8 OAP61289.1 - 0.015 15.5 1.3 0.015 15.5 1.3 1.4 2 0 0 2 2 2 0 Small nuclear RNA activating complex subunit 2, SNAP190 Myb Chorismate_bind PF00425.18 OAP61290.1 - 1.4e-62 211.6 0.2 4e-62 210.1 0.2 1.7 1 1 0 1 1 1 1 chorismate binding enzyme GATase PF00117.28 OAP61290.1 - 3.6e-27 95.4 0.0 2.3e-18 66.6 0.0 2.2 2 0 0 2 2 2 2 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.13 OAP61290.1 - 5.1e-18 65.6 0.1 2.3e-17 63.5 0.0 2.2 3 0 0 3 3 3 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.13 OAP61290.1 - 1.3e-06 28.3 0.1 0.02 14.7 0.0 2.4 2 0 0 2 2 2 2 Peptidase C26 Methyltransf_25 PF13649.6 OAP61291.1 - 1.1e-24 86.9 0.0 2.6e-24 85.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAP61291.1 - 1.1e-23 83.7 0.0 2e-23 82.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAP61291.1 - 7.9e-21 74.4 0.0 1.1e-20 73.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAP61291.1 - 1.8e-15 57.5 0.0 4.9e-15 56.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAP61291.1 - 3.7e-13 49.3 0.0 6.2e-13 48.6 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 OAP61291.1 - 2e-12 47.2 0.0 3.2e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OAP61291.1 - 2.9e-07 30.2 0.0 4.9e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 OAP61291.1 - 1.4e-05 25.0 0.0 1.9e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.12 OAP61291.1 - 1.7e-05 24.5 0.0 7.4e-05 22.4 0.0 1.8 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW CheR PF01739.18 OAP61291.1 - 2.1e-05 24.1 0.0 0.0014 18.2 0.0 2.3 1 1 1 2 2 2 1 CheR methyltransferase, SAM binding domain NodS PF05401.11 OAP61291.1 - 0.00016 21.4 0.0 0.00052 19.7 0.0 1.7 1 1 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_32 PF13679.6 OAP61291.1 - 0.0019 18.2 0.0 0.003 17.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 OAP61291.1 - 0.002 18.0 0.0 0.017 15.0 0.0 2.0 2 0 0 2 2 2 1 Hypothetical methyltransferase CMAS PF02353.20 OAP61291.1 - 0.002 17.5 0.0 0.0069 15.7 0.0 1.9 2 1 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.11 OAP61291.1 - 0.0028 16.7 0.0 0.0048 15.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_4 PF02390.17 OAP61291.1 - 0.0031 17.0 0.0 0.064 12.7 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase DUF938 PF06080.12 OAP61291.1 - 0.0045 16.8 0.0 0.0071 16.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_18 PF12847.7 OAP61291.1 - 0.009 16.0 0.0 0.014 15.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 OAP61291.1 - 0.015 14.4 0.0 0.021 13.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase FtsJ PF01728.19 OAP61291.1 - 0.015 15.4 0.0 0.044 13.9 0.0 1.7 1 1 0 1 1 1 0 FtsJ-like methyltransferase PrmA PF06325.13 OAP61291.1 - 0.015 14.7 0.0 0.022 14.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_PK PF05891.12 OAP61291.1 - 0.028 13.9 0.0 0.046 13.2 0.0 1.3 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Methyltransf_29 PF03141.16 OAP61291.1 - 0.034 12.7 0.0 0.067 11.7 0.0 1.6 1 1 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_24 PF13578.6 OAP61291.1 - 0.049 14.6 0.1 0.23 12.5 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Methyltr_RsmB-F PF01189.17 OAP61291.1 - 0.082 12.5 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F DUF3684 PF12449.8 OAP61292.1 - 0 1386.1 0.0 0 1385.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) HATPase_c_3 PF13589.6 OAP61292.1 - 8e-06 25.7 0.0 1.7e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TRAPPC9-Trs120 PF08626.11 OAP61293.1 - 3.6e-300 998.5 0.0 4.1e-300 998.3 0.0 1.0 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit HA2 PF04408.23 OAP61294.1 - 5.2e-21 75.0 0.1 5.2e-21 75.0 0.1 3.5 4 0 0 4 4 4 1 Helicase associated domain (HA2) Helicase_C PF00271.31 OAP61294.1 - 3.9e-11 43.3 0.0 2.1e-10 40.9 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 OAP61294.1 - 3.6e-09 36.6 0.0 9.7e-08 32.0 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.16 OAP61294.1 - 4.3e-08 33.4 0.0 9.4e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_19 PF13245.6 OAP61294.1 - 0.00022 21.6 0.0 0.0005 20.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 OAP61294.1 - 0.00083 19.6 0.0 0.0043 17.3 0.0 2.3 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 OAP61294.1 - 0.0036 17.0 0.0 0.0078 15.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 OAP61294.1 - 0.026 13.8 1.0 0.067 12.4 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) T2SSE PF00437.20 OAP61294.1 - 0.063 12.3 0.0 0.14 11.2 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_23 PF13476.6 OAP61294.1 - 0.24 11.9 19.1 0.28 11.7 0.0 3.3 4 0 0 4 4 3 0 AAA domain FANC_SAP PF18081.1 OAP61294.1 - 0.9 9.8 3.2 9.5 6.5 0.4 3.2 2 0 0 2 2 2 0 Fanconi anemia-associated nuclease SAP domain APH PF01636.23 OAP61295.1 - 2e-14 54.1 0.0 7.8e-13 48.9 0.0 2.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family DUF1679 PF07914.11 OAP61295.1 - 0.0004 19.4 0.0 0.0037 16.2 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1679) Choline_kinase PF01633.20 OAP61295.1 - 0.00069 19.3 0.2 0.0015 18.2 0.0 1.6 2 0 0 2 2 2 1 Choline/ethanolamine kinase EcKinase PF02958.20 OAP61295.1 - 0.092 12.0 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase T5orf172 PF10544.9 OAP61296.1 - 5.2e-18 65.5 1.2 1.1e-17 64.4 1.2 1.6 1 0 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 OAP61296.1 - 1.8e-11 44.6 1.5 3.7e-11 43.5 1.5 1.6 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 HET PF06985.11 OAP61297.1 - 2.2e-12 47.5 6.2 1e-09 38.9 0.9 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Pkinase_Tyr PF07714.17 OAP61299.1 - 5.1e-08 32.5 0.0 7.6e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OAP61299.1 - 8.7e-08 31.8 0.1 1.5e-07 31.1 0.1 1.4 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.23 OAP61299.1 - 0.046 13.6 0.7 0.14 12.1 0.4 1.7 1 1 0 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 OAP61299.1 - 0.086 12.4 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 OAP61299.1 - 0.13 11.6 0.4 0.18 11.1 0.4 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family p450 PF00067.22 OAP61300.1 - 1.2e-53 182.5 0.0 4.5e-53 180.6 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 CRCB PF02537.15 OAP61301.1 - 2.3e-35 120.8 8.0 1.5e-20 73.3 6.6 2.3 2 0 0 2 2 2 2 CrcB-like protein, Camphor Resistance (CrcB) adh_short_C2 PF13561.6 OAP61302.1 - 4.5e-62 209.7 0.1 5.1e-62 209.5 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP61302.1 - 2.3e-41 141.4 0.1 2.7e-41 141.2 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAP61302.1 - 4.3e-13 49.6 0.0 6.3e-13 49.0 0.0 1.2 1 0 0 1 1 1 1 KR domain Phosphodiest PF01663.22 OAP61303.1 - 5.4e-16 59.1 0.1 9.2e-16 58.4 0.1 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 OAP61303.1 - 0.00013 21.5 0.0 0.00022 20.7 0.0 1.4 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.18 OAP61303.1 - 0.00028 20.4 0.6 0.00059 19.3 0.6 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily Gly-zipper_YMGG PF13441.6 OAP61303.1 - 0.2 11.4 11.4 0.5 10.1 11.4 1.6 1 0 0 1 1 1 0 YMGG-like Gly-zipper Gly-zipper_Omp PF13488.6 OAP61303.1 - 0.25 11.3 14.0 0.75 9.8 14.0 1.8 1 0 0 1 1 1 0 Glycine zipper PglZ PF08665.12 OAP61303.1 - 0.29 11.2 0.7 15 5.7 0.1 2.3 2 0 0 2 2 2 0 PglZ domain zf-CCCH PF00642.24 OAP61304.1 - 1.9e-08 34.0 2.5 3.4e-08 33.2 2.5 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-RING_UBOX PF13445.6 OAP61304.1 - 9.1e-08 32.0 5.3 1.9e-07 30.9 5.3 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 OAP61304.1 - 2.5e-07 30.5 5.6 4.7e-07 29.6 5.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OAP61304.1 - 1.4e-06 28.0 8.2 2.6e-06 27.2 8.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf_CCCH_4 PF18345.1 OAP61304.1 - 1.8e-05 24.6 6.2 3.5e-05 23.7 6.2 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-RING_5 PF14634.6 OAP61304.1 - 2.1e-05 24.4 8.2 3.9e-05 23.5 8.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 OAP61304.1 - 2.2e-05 24.2 9.8 4.1e-05 23.4 9.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 OAP61304.1 - 7.3e-05 22.8 3.0 7.3e-05 22.8 3.0 1.7 2 0 0 2 2 1 1 zinc RING finger of MSL2 zf-CCCH_4 PF18044.1 OAP61304.1 - 0.00019 21.1 2.6 0.00019 21.1 2.6 1.7 2 0 0 2 2 1 1 CCCH-type zinc finger zf-RING_2 PF13639.6 OAP61304.1 - 0.00039 20.7 6.8 0.00072 19.8 6.8 1.5 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 OAP61304.1 - 0.00096 19.0 6.1 0.0018 18.1 6.1 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 DUF903 PF06004.12 OAP61304.1 - 0.0056 16.5 1.0 0.015 15.2 0.0 2.2 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF903) zf-C3HC4_4 PF15227.6 OAP61304.1 - 0.0092 16.1 8.1 0.022 14.9 8.1 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING NADH_4Fe-4S PF10589.9 OAP61304.1 - 0.021 14.9 0.2 2.3 8.3 0.1 2.5 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region zf-CCCH_2 PF14608.6 OAP61304.1 - 0.081 13.4 3.6 0.17 12.4 3.6 1.6 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger CN_hydrolase PF00795.22 OAP61305.1 - 1.5e-18 67.1 0.1 4.7e-17 62.2 0.0 2.1 2 0 0 2 2 2 2 Carbon-nitrogen hydrolase Uso1_p115_C PF04871.13 OAP61305.1 - 0.11 12.9 4.0 0.17 12.3 4.0 1.2 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region HLH PF00010.26 OAP61306.1 - 7.6e-11 41.8 0.8 1.3e-10 41.1 0.8 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain TACC_C PF05010.14 OAP61306.1 - 0.023 14.5 0.5 0.031 14.0 0.5 1.1 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF724 PF05266.14 OAP61306.1 - 0.14 12.0 0.6 0.18 11.6 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) ERM PF00769.19 OAP61306.1 - 0.16 11.8 3.7 0.28 11.0 3.7 1.5 1 1 0 1 1 1 0 Ezrin/radixin/moesin family APG6_N PF17675.1 OAP61306.1 - 1.1 9.8 3.7 1.7 9.1 3.7 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF2235 PF09994.9 OAP61307.1 - 2.9e-75 253.3 0.0 5.1e-75 252.5 0.0 1.4 2 0 0 2 2 2 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) But2 PF09792.9 OAP61308.1 - 3.8e-38 131.1 0.5 6.3e-38 130.4 0.2 1.5 2 0 0 2 2 2 1 Ubiquitin 3 binding protein But2 C-terminal domain GATase_6 PF13522.6 OAP61309.1 - 5.4e-15 55.8 0.0 1.6e-14 54.2 0.0 1.9 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 OAP61309.1 - 8e-13 48.4 0.0 2.8e-12 46.6 0.0 2.0 2 0 0 2 2 2 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 OAP61309.1 - 1.4e-08 34.4 0.1 2.9e-08 33.4 0.1 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.6 OAP61309.1 - 0.0013 17.7 0.0 0.0036 16.3 0.0 1.7 2 0 0 2 2 2 1 Glutamine amidotransferases class-II PRTase_2 PF15609.6 OAP61309.1 - 0.041 13.4 0.0 0.11 12.0 0.0 1.6 1 1 0 1 1 1 0 Phosphoribosyl transferase DNA_methylase PF00145.17 OAP61310.1 - 3.7e-39 135.0 0.0 1.4e-26 93.6 0.0 2.1 1 1 1 2 2 2 2 C-5 cytosine-specific DNA methylase Methyltransf_15 PF09445.10 OAP61310.1 - 0.072 12.7 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase PrmA PF06325.13 OAP61310.1 - 0.12 11.7 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) RNase_PH PF01138.21 OAP61311.1 - 4.9e-19 69.1 0.0 1.6e-18 67.5 0.0 1.8 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 FAD_binding_3 PF01494.19 OAP61312.1 - 5e-70 236.5 0.0 7.5e-70 235.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 OAP61312.1 - 6e-46 156.5 0.0 1.2e-45 155.5 0.0 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain DAO PF01266.24 OAP61312.1 - 6e-05 22.8 1.1 0.058 13.0 0.9 3.1 1 1 0 2 2 2 1 FAD dependent oxidoreductase SE PF08491.10 OAP61312.1 - 0.0041 16.2 0.0 0.048 12.7 0.0 2.0 1 1 0 1 1 1 1 Squalene epoxidase FAD_binding_2 PF00890.24 OAP61312.1 - 0.022 13.8 0.7 0.048 12.7 0.7 1.5 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 OAP61312.1 - 0.023 13.9 0.0 0.036 13.3 0.0 1.3 1 0 0 1 1 1 0 Thi4 family NAD_binding_8 PF13450.6 OAP61312.1 - 0.076 13.3 0.0 0.4 10.9 0.0 2.2 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAP61312.1 - 0.12 11.5 0.0 0.3 10.3 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Phosphodiest PF01663.22 OAP61313.1 - 9.4e-14 51.8 1.8 4.2e-09 36.5 0.0 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 OAP61313.1 - 0.028 13.8 0.2 0.084 12.3 0.0 1.8 2 0 0 2 2 2 0 Sulfatase Methyltransf_23 PF13489.6 OAP61314.1 - 2.9e-14 53.2 0.0 4.3e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAP61314.1 - 0.0015 19.2 0.0 0.0042 17.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAP61314.1 - 0.006 17.2 0.0 0.014 16.1 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAP61314.1 - 0.012 16.4 0.0 0.065 14.0 0.0 2.2 2 1 0 2 2 2 0 Methyltransferase domain p450 PF00067.22 OAP61315.1 - 3.3e-69 233.8 0.0 3.7e-69 233.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF2189 PF09955.9 OAP61315.1 - 0.025 14.8 0.3 0.1 12.9 0.0 2.1 2 0 0 2 2 2 0 Predicted integral membrane protein (DUF2189) SAP PF02037.27 OAP61316.1 - 7e-08 32.0 0.2 1.4e-07 31.1 0.2 1.5 1 0 0 1 1 1 1 SAP domain RAI1 PF08652.11 OAP61317.1 - 2.6e-25 88.4 0.0 1.1e-24 86.4 0.0 2.0 2 0 0 2 2 2 1 RAI1 like PD-(D/E)XK nuclease CEP76-C2 PF15627.6 OAP61317.1 - 0.0054 16.3 0.1 0.047 13.2 0.0 2.1 2 0 0 2 2 2 1 CEP76 C2 domain LT-IIB PF06453.11 OAP61317.1 - 0.13 12.2 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Type II heat-labile enterotoxin , B subunit (LT-IIB) IPPT PF01715.17 OAP61318.1 - 5.8e-58 196.4 0.1 7.7e-58 196.0 0.1 1.1 1 0 0 1 1 1 1 IPP transferase AAA_33 PF13671.6 OAP61318.1 - 1.8e-05 24.9 0.3 0.0014 18.8 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 OAP61318.1 - 1.9e-05 25.2 0.7 0.018 15.6 0.0 3.0 2 1 1 3 3 3 1 AAA domain IPT PF01745.16 OAP61318.1 - 9.2e-05 21.9 0.0 0.00017 21.1 0.0 1.4 1 0 0 1 1 1 1 Isopentenyl transferase zf-C2H2_6 PF13912.6 OAP61318.1 - 0.0014 18.6 0.4 0.0014 18.6 0.4 1.9 2 0 0 2 2 2 1 C2H2-type zinc finger AAA_16 PF13191.6 OAP61318.1 - 0.0015 18.9 0.5 0.021 15.2 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_28 PF13521.6 OAP61318.1 - 0.0064 16.7 0.9 0.072 13.3 0.0 2.7 2 1 1 3 3 3 1 AAA domain AAA_22 PF13401.6 OAP61318.1 - 0.0083 16.4 0.0 0.086 13.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain zf-C2H2_jaz PF12171.8 OAP61318.1 - 0.012 15.9 0.0 0.022 15.1 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 OAP61318.1 - 0.029 14.7 0.0 0.056 13.8 0.0 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 OAP61318.1 - 0.033 14.6 0.1 0.056 13.8 0.1 1.4 1 0 0 1 1 1 0 Zinc-finger of C2H2 type AAA_5 PF07728.14 OAP61318.1 - 0.04 13.9 0.0 0.083 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 OAP61318.1 - 0.056 13.4 0.1 2.6 8.0 0.0 2.4 2 0 0 2 2 2 0 NACHT domain AAA PF00004.29 OAP61318.1 - 0.076 13.4 0.0 0.17 12.3 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) GAGA PF09237.11 OAP61318.1 - 0.087 12.6 0.0 0.21 11.4 0.0 1.7 1 0 0 1 1 1 0 GAGA factor Hpr_kinase_C PF07475.12 OAP61318.1 - 0.1 12.1 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain PhoH PF02562.16 OAP61318.1 - 0.15 11.5 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein RNA_helicase PF00910.22 OAP61318.1 - 0.16 12.4 0.0 0.37 11.2 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Torus PF16131.5 OAP61319.1 - 1.8e-43 147.6 0.4 4.1e-43 146.5 0.0 1.8 2 0 0 2 2 2 1 Torus domain RRM_1 PF00076.22 OAP61319.1 - 9.8e-08 31.7 0.0 1.8e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 OAP61319.1 - 0.00015 21.7 1.9 0.00027 20.9 1.9 1.5 1 0 0 1 1 1 1 Zinc finger domain Nup35_RRM_2 PF14605.6 OAP61319.1 - 0.0072 16.3 0.0 0.016 15.2 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif zf-CCCH PF00642.24 OAP61319.1 - 0.11 12.4 2.2 0.19 11.7 2.2 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Glyco_hydro_63 PF03200.16 OAP61320.1 - 1.6e-165 551.6 0.7 2.7e-164 547.6 0.0 2.5 2 1 0 2 2 2 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 OAP61320.1 - 1.9e-81 273.5 0.0 6.5e-81 271.7 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 63 N-terminal domain TEX33 PF15400.6 OAP61320.1 - 0.12 12.9 0.0 0.32 11.5 0.0 1.7 2 0 0 2 2 2 0 Testis-expressed sequence 33 protein family Pkinase PF00069.25 OAP61321.1 - 3.8e-67 226.4 0.0 3.9e-34 118.2 0.0 3.6 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 OAP61321.1 - 3.7e-37 128.0 0.0 1.2e-16 60.8 0.0 3.3 3 0 0 3 3 3 3 Protein tyrosine kinase HGTP_anticodon2 PF12745.7 OAP61321.1 - 4.8e-18 65.6 6.2 3.3e-17 62.9 0.0 2.6 3 0 0 3 3 3 1 Anticodon binding domain of tRNAs tRNA-synt_His PF13393.6 OAP61321.1 - 2e-15 56.9 0.5 6.9e-14 51.8 0.0 2.3 2 0 0 2 2 2 1 Histidyl-tRNA synthetase RWD PF05773.22 OAP61321.1 - 9.5e-13 48.4 0.0 5.7e-12 45.9 0.0 2.3 2 0 0 2 2 2 1 RWD domain APH PF01636.23 OAP61321.1 - 0.00064 19.7 0.0 0.0029 17.6 0.0 2.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 OAP61321.1 - 0.011 15.1 0.1 0.32 10.3 0.0 2.7 3 0 0 3 3 3 0 Kinase-like DUF1682 PF07946.14 OAP61321.1 - 0.4 9.8 8.3 0.69 9.1 8.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) MMR_HSR1_Xtn PF16897.5 OAP61322.1 - 1.8e-34 117.9 0.7 4.3e-34 116.7 0.3 1.8 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 OAP61322.1 - 3.7e-21 75.3 0.0 8.3e-21 74.2 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.21 OAP61322.1 - 4.2e-21 74.8 0.6 7.4e-21 74.0 0.1 1.7 2 0 0 2 2 2 1 TGS domain FeoB_N PF02421.18 OAP61322.1 - 9.6e-14 51.2 0.0 1.6e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 OAP61322.1 - 3.9e-05 23.8 0.2 0.053 13.6 0.0 2.4 1 1 1 2 2 2 2 Dynamin family AIG1 PF04548.16 OAP61322.1 - 0.013 14.8 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 AIG1 family MeaB PF03308.16 OAP61322.1 - 0.087 11.8 0.0 0.22 10.5 0.0 1.6 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MCM PF00493.23 OAP61322.1 - 0.1 11.6 0.1 0.24 10.5 0.0 1.5 2 0 0 2 2 2 0 MCM P-loop domain AAA_18 PF13238.6 OAP61322.1 - 0.15 12.7 0.0 4.2 7.9 0.0 2.5 1 1 0 2 2 2 0 AAA domain DAO PF01266.24 OAP61323.1 - 6e-62 210.3 0.8 7.2e-62 210.0 0.8 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAP61323.1 - 0.0001 22.4 0.4 0.00028 21.0 0.4 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAP61323.1 - 0.0016 17.7 0.0 0.012 14.9 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAP61323.1 - 0.011 16.3 0.0 0.028 15.0 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 OAP61323.1 - 0.018 13.9 0.1 0.091 11.6 0.1 1.8 2 0 0 2 2 2 0 Tryptophan halogenase MCRA PF06100.11 OAP61323.1 - 0.025 13.4 0.1 0.041 12.7 0.1 1.2 1 0 0 1 1 1 0 MCRA family NAD_binding_9 PF13454.6 OAP61323.1 - 0.12 12.4 0.2 0.89 9.5 0.1 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding Thi4 PF01946.17 OAP61323.1 - 0.17 11.1 0.1 0.3 10.3 0.1 1.3 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.22 OAP61323.1 - 0.2 10.7 0.0 4.4 6.3 0.0 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A CRT10 PF08728.10 OAP61324.1 - 2e-18 66.0 0.1 3.3e-11 42.1 0.0 2.7 3 0 0 3 3 3 2 CRT10 MMtag PF10159.9 OAP61325.1 - 4.5e-34 116.6 3.4 7.2e-34 115.9 3.4 1.3 1 0 0 1 1 1 1 Multiple myeloma tumor-associated adh_short PF00106.25 OAP61326.1 - 8.6e-23 80.8 0.0 1.9e-22 79.7 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP61326.1 - 6.1e-16 58.7 0.0 1.1e-15 57.9 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase CLPTM1 PF05602.12 OAP61327.1 - 3.4e-161 537.1 0.3 4.1e-161 536.8 0.3 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) DUF1453 PF07301.11 OAP61327.1 - 0.0095 15.9 0.9 0.74 9.8 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1453) 2TM PF13239.6 OAP61327.1 - 0.28 11.5 2.2 2.3 8.6 0.1 2.9 2 0 0 2 2 2 0 2TM domain DUF1240 PF06836.12 OAP61327.1 - 1.2 9.7 4.7 4.5 7.9 4.7 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1240) eIF-5_eIF-2B PF01873.17 OAP61328.1 - 0.018 14.9 2.3 0.026 14.4 2.3 1.2 1 0 0 1 1 1 0 Domain found in IF2B/IF5 Transcrip_reg PF01709.20 OAP61330.1 - 2.6e-61 207.1 1.9 2.9e-61 207.0 1.9 1.0 1 0 0 1 1 1 1 Transcriptional regulator LAL_C2 PF18603.1 OAP61330.1 - 0.0068 16.5 0.2 0.97 9.6 0.0 3.4 4 0 0 4 4 4 1 L-amino acid ligase C-terminal domain 2 DUF4258 PF14076.6 OAP61330.1 - 0.01 16.2 0.0 0.066 13.6 0.0 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4258) DUF3646 PF12362.8 OAP61330.1 - 0.052 13.9 0.2 0.097 13.0 0.2 1.4 1 0 0 1 1 1 0 DNA polymerase III gamma and tau subunits C terminal PTR2 PF00854.21 OAP61331.1 - 1.5e-69 234.7 2.7 2.3e-69 234.1 2.7 1.2 1 0 0 1 1 1 1 POT family Vps51 PF08700.11 OAP61331.1 - 2e-09 37.4 0.2 9.7e-09 35.2 0.0 2.3 2 0 0 2 2 2 1 Vps51/Vps67 MFS_1 PF07690.16 OAP61331.1 - 3.6e-06 26.2 25.1 3.6e-06 26.2 25.1 2.6 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF3112 PF11309.8 OAP61331.1 - 0.18 11.2 0.8 0.44 10.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3112) Rubis-subs-bind PF09273.11 OAP61331.1 - 0.24 12.1 2.3 0.45 11.2 0.5 2.4 2 0 0 2 2 2 0 Rubisco LSMT substrate-binding Sugar_tr PF00083.24 OAP61331.1 - 1.6 7.5 19.7 0.81 8.5 4.0 3.5 3 1 0 3 3 3 0 Sugar (and other) transporter FUN14 PF04930.15 OAP61332.1 - 3.3e-07 30.6 0.4 5.6e-07 29.9 0.4 1.3 1 0 0 1 1 1 1 FUN14 family DUF1622 PF07784.11 OAP61332.1 - 0.2 11.6 1.9 16 5.5 0.3 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1622) FAD_binding_3 PF01494.19 OAP61333.1 - 1e-79 268.3 0.0 1.6e-79 267.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain RVT_thumb PF06817.14 OAP61335.1 - 0.061 13.2 0.1 0.13 12.1 0.1 1.5 1 0 0 1 1 1 0 Reverse transcriptase thumb domain TPR_MLP1_2 PF07926.12 OAP61336.1 - 8.5e-07 29.1 41.8 0.0043 17.1 5.2 4.7 4 0 0 4 4 4 4 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 OAP61336.1 - 0.006 15.5 37.2 0.028 13.3 10.3 3.4 1 1 3 4 4 4 2 Spc7 kinetochore protein LMP PF04778.12 OAP61336.1 - 0.0092 15.9 11.6 0.13 12.2 0.4 3.5 3 0 0 3 3 3 1 LMP repeated region ZapB PF06005.12 OAP61336.1 - 0.026 14.9 42.5 0.33 11.4 4.5 5.8 5 1 1 6 6 5 0 Cell division protein ZapB MAD PF05557.13 OAP61336.1 - 0.067 11.5 37.5 0.13 10.6 2.9 3.1 1 1 1 2 2 2 0 Mitotic checkpoint protein DUF1075 PF06388.11 OAP61336.1 - 0.1 12.7 0.1 0.37 10.8 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1075) DUF4200 PF13863.6 OAP61336.1 - 0.23 11.9 33.5 0.61 10.5 1.8 4.6 3 1 2 5 5 5 0 Domain of unknown function (DUF4200) Csm1_N PF18504.1 OAP61336.1 - 0.27 11.6 32.0 0.55 10.6 4.5 5.8 5 1 1 6 6 6 0 Csm1 N-terminal domain Leu_zip PF15294.6 OAP61336.1 - 0.62 9.5 29.0 1.5 8.3 9.2 2.6 1 1 0 2 2 2 0 Leucine zipper TSC22 PF01166.18 OAP61336.1 - 0.93 9.9 15.9 1.2 9.5 0.3 5.2 5 0 0 5 5 5 0 TSC-22/dip/bun family Fez1 PF06818.15 OAP61336.1 - 0.93 9.9 40.6 1.8 9.0 18.4 3.0 1 1 0 2 2 2 0 Fez1 BLOC1_2 PF10046.9 OAP61336.1 - 1.2 9.5 22.2 0.3 11.4 2.8 4.3 4 0 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Seryl_tRNA_N PF02403.22 OAP61336.1 - 1.6 9.0 24.3 0.81 9.9 1.5 5.1 3 1 1 4 4 4 0 Seryl-tRNA synthetase N-terminal domain SHE3 PF17078.5 OAP61336.1 - 1.9 8.1 25.8 7.9 6.1 2.4 3.5 2 1 1 3 3 3 0 SWI5-dependent HO expression protein 3 Mod_r PF07200.13 OAP61336.1 - 2.1 8.4 38.4 0.55 10.3 5.9 3.9 1 1 3 4 4 4 0 Modifier of rudimentary (Mod(r)) protein DASH_Dam1 PF08653.10 OAP61336.1 - 4 7.3 6.2 19 5.1 0.7 3.4 3 0 0 3 3 3 0 DASH complex subunit Dam1 YabA PF06156.13 OAP61336.1 - 4.6 7.9 29.2 26 5.5 4.2 4.9 1 1 2 3 3 3 0 Initiation control protein YabA Acyl-CoA_dh_2 PF08028.11 OAP61336.1 - 5.3 7.3 17.3 3 8.1 0.3 4.2 3 1 0 4 4 4 0 Acyl-CoA dehydrogenase, C-terminal domain Rootletin PF15035.6 OAP61336.1 - 8.6 6.3 43.9 1.7 8.6 4.6 4.0 1 1 3 4 4 4 0 Ciliary rootlet component, centrosome cohesion DUF4140 PF13600.6 OAP61336.1 - 9.4 6.7 31.1 0.71 10.3 1.4 5.0 3 1 0 4 4 4 0 N-terminal domain of unknown function (DUF4140) GATase PF00117.28 OAP61337.1 - 3e-46 157.6 0.0 4.1e-46 157.2 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.22 OAP61337.1 - 5.5e-45 152.3 0.0 1.1e-44 151.4 0.0 1.5 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase small chain, CPSase domain Peptidase_C26 PF07722.13 OAP61337.1 - 8.3e-05 22.4 0.2 0.003 17.4 0.2 2.4 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.24 OAP61337.1 - 0.013 15.3 0.0 0.023 14.5 0.0 1.3 1 0 0 1 1 1 0 DJ-1/PfpI family Zn_clus PF00172.18 OAP61338.1 - 0.012 15.7 0.6 0.021 14.9 0.6 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAP61341.1 - 2.5e-14 53.0 1.0 4.4e-14 52.2 0.1 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain MFS_1 PF07690.16 OAP61342.1 - 9.5e-23 80.7 43.1 9.5e-23 80.7 43.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily D123 PF07065.14 OAP61343.1 - 1.3e-112 375.9 0.1 1.6e-112 375.6 0.1 1.1 1 0 0 1 1 1 1 D123 Cut12 PF11500.8 OAP61344.1 - 1.3e-07 31.6 3.9 3.5e-07 30.3 3.9 1.7 1 0 0 1 1 1 1 Spindle pole body formation-associated protein HAUS-augmin3 PF14932.6 OAP61344.1 - 0.003 17.2 0.4 0.0083 15.7 0.3 1.6 1 1 0 1 1 1 1 HAUS augmin-like complex subunit 3 KASH_CCD PF14662.6 OAP61344.1 - 0.033 14.0 1.0 0.06 13.2 1.0 1.4 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH IFT20 PF14931.6 OAP61344.1 - 0.052 13.7 2.4 0.11 12.7 2.4 1.5 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 Tho2 PF11262.8 OAP61344.1 - 0.57 9.3 2.5 0.92 8.6 2.5 1.3 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Myc-LZ PF02344.15 OAP61344.1 - 0.99 9.6 6.9 0.22 11.7 1.3 2.3 2 0 0 2 2 2 0 Myc leucine zipper domain Macoilin PF09726.9 OAP61344.1 - 1.1 7.8 10.3 0.043 12.4 1.1 2.0 1 1 1 2 2 2 0 Macoilin family ZapB PF06005.12 OAP61344.1 - 1.2 9.6 6.2 0.47 10.9 2.5 2.1 2 0 0 2 2 2 0 Cell division protein ZapB DUF1640 PF07798.11 OAP61345.1 - 2.4e-32 112.4 6.9 2.4e-32 112.4 6.9 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1640) DUF4407 PF14362.6 OAP61345.1 - 0.0043 16.5 6.4 0.0043 16.5 6.4 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4407) HA2 PF04408.23 OAP61345.1 - 2.9 8.2 6.4 3.1 8.1 0.2 3.0 3 0 0 3 3 3 0 Helicase associated domain (HA2) 2-Hacid_dh_C PF02826.19 OAP61346.1 - 1.2e-50 171.3 0.0 2.5e-50 170.3 0.0 1.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 OAP61346.1 - 7.7e-16 58.0 0.0 1.1e-15 57.5 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 OAP61346.1 - 0.0016 18.7 0.0 0.0045 17.2 0.0 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase FmiP_Thoc5 PF09766.9 OAP61347.1 - 5.2e-05 22.7 3.6 5.8e-05 22.5 3.6 1.1 1 0 0 1 1 1 1 Fms-interacting protein/Thoc5 DUF2722 PF10846.8 OAP61347.1 - 5.8e-05 22.2 7.1 5.8e-05 22.2 7.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Pex14_N PF04695.13 OAP61347.1 - 0.00071 20.3 8.8 0.0012 19.6 8.8 1.3 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Spt20 PF12090.8 OAP61347.1 - 0.0044 16.7 19.7 0.0054 16.4 19.7 1.1 1 0 0 1 1 1 1 Spt20 family Pannexin_like PF12534.8 OAP61347.1 - 0.008 15.3 1.3 0.0086 15.2 1.3 1.1 1 0 0 1 1 1 1 Pannexin-like TM region of LRRC8 ORC5_C PF14630.6 OAP61347.1 - 0.0095 15.5 1.1 0.013 15.0 1.1 1.1 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus Suf PF05843.14 OAP61347.1 - 0.011 15.8 6.0 0.013 15.5 6.0 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) EIIBC-GUT_N PF03612.14 OAP61347.1 - 0.017 14.9 2.2 0.022 14.5 2.2 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Dpy19 PF10034.9 OAP61347.1 - 0.026 12.8 1.2 0.03 12.6 1.2 1.0 1 0 0 1 1 1 0 Q-cell neuroblast polarisation Presenilin PF01080.17 OAP61347.1 - 0.029 13.2 1.4 0.034 12.9 1.4 1.2 1 0 0 1 1 1 0 Presenilin Connexin PF00029.19 OAP61347.1 - 0.056 13.2 0.9 0.068 12.9 0.9 1.1 1 0 0 1 1 1 0 Connexin DUF3464 PF11947.8 OAP61347.1 - 0.066 13.0 3.3 0.09 12.5 3.3 1.2 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 RICTOR_N PF14664.6 OAP61347.1 - 0.071 12.1 1.5 0.081 11.9 1.5 1.2 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, N-term FHIPEP PF00771.20 OAP61347.1 - 0.13 10.7 2.8 0.17 10.4 2.8 1.1 1 0 0 1 1 1 0 FHIPEP family DUF2232 PF09991.9 OAP61347.1 - 0.14 11.3 0.7 0.18 11.0 0.7 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) OATP PF03137.20 OAP61347.1 - 0.44 8.8 1.5 0.53 8.5 1.5 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family CLN3 PF02487.17 OAP61347.1 - 0.44 9.5 1.5 0.5 9.4 1.5 1.1 1 0 0 1 1 1 0 CLN3 protein TFIIA PF03153.13 OAP61347.1 - 0.75 9.7 19.9 0.92 9.4 19.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PIEZO PF15917.5 OAP61347.1 - 0.97 8.9 12.0 6.1 6.3 0.0 2.1 2 0 0 2 2 2 0 Piezo AIF_C PF14721.6 OAP61347.1 - 1.3 9.4 4.7 1.9 8.8 4.7 1.2 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term UPF0560 PF10577.9 OAP61347.1 - 1.3 7.4 9.3 1.5 7.2 9.3 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Dicty_REP PF05086.12 OAP61347.1 - 1.6 6.6 4.1 1.8 6.4 4.1 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Peptidase_S49_N PF08496.10 OAP61347.1 - 4.5 7.3 9.6 6.7 6.8 9.6 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal TERB2 PF15101.6 OAP61347.1 - 5.2 7.1 12.1 2.9 7.9 10.4 1.4 2 0 0 2 2 1 0 Telomere-associated protein TERB2 DUF4834 PF16118.5 OAP61347.1 - 6.1 7.9 10.5 11 7.0 10.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) F-box PF00646.33 OAP61348.1 - 1.2e-06 28.2 0.8 6.5e-06 25.9 0.5 2.3 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 OAP61348.1 - 3.1e-05 23.8 0.4 8.3e-05 22.4 0.4 1.8 1 0 0 1 1 1 1 F-box-like Herpes_gE PF02480.16 OAP61348.1 - 0.035 12.9 0.0 0.052 12.3 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E SOR_SNZ PF01680.17 OAP61349.1 - 3.7e-106 353.5 7.4 5e-106 353.1 7.4 1.2 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.14 OAP61349.1 - 2e-07 30.6 11.2 2.1e-06 27.3 2.3 2.4 2 1 0 2 2 2 2 Thiazole biosynthesis protein ThiG Dus PF01207.17 OAP61349.1 - 0.00011 21.4 0.3 0.084 11.9 0.1 2.5 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) NanE PF04131.14 OAP61349.1 - 0.0013 18.0 0.9 0.026 13.7 0.0 2.6 2 2 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase His_biosynth PF00977.21 OAP61349.1 - 0.0021 17.6 0.8 0.068 12.6 0.0 2.9 2 1 1 3 3 3 1 Histidine biosynthesis protein IGPS PF00218.21 OAP61349.1 - 0.011 14.9 0.1 0.4 9.8 0.0 2.4 2 1 0 2 2 2 0 Indole-3-glycerol phosphate synthase TetR_C_27 PF17935.1 OAP61349.1 - 0.042 13.9 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain NMO PF03060.15 OAP61349.1 - 0.13 11.6 11.6 0.099 12.0 3.5 2.2 2 0 0 2 2 2 0 Nitronate monooxygenase ORC2 PF04084.14 OAP61350.1 - 1e-111 373.1 0.0 1.7e-111 372.3 0.0 1.4 1 1 0 1 1 1 1 Origin recognition complex subunit 2 Cohesin_HEAT PF12765.7 OAP61350.1 - 0.2 12.0 0.6 1.6 9.1 0.1 2.3 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion Cwf_Cwc_15 PF04889.12 OAP61350.1 - 0.3 10.8 26.8 0.58 9.9 14.7 2.4 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein ArgJ PF01960.18 OAP61351.1 - 1.8e-147 491.0 1.6 2.1e-147 490.8 1.6 1.0 1 0 0 1 1 1 1 ArgJ family HTH_16 PF12645.7 OAP61351.1 - 0.14 12.2 0.0 0.44 10.6 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain SecY PF00344.20 OAP61352.1 - 2.1e-71 240.7 7.8 2.6e-71 240.4 7.8 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 OAP61352.1 - 2.4e-17 62.5 0.3 6.7e-17 61.0 0.3 1.9 1 0 0 1 1 1 1 Plug domain of Sec61p FMN_bind_2 PF04299.12 OAP61353.1 - 1.8e-57 193.7 0.2 2.4e-57 193.3 0.2 1.1 1 0 0 1 1 1 1 Putative FMN-binding domain SEN1_N PF12726.7 OAP61354.1 - 3.7e-181 604.1 9.7 4.8e-181 603.7 9.7 1.1 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.6 OAP61354.1 - 8.1e-71 238.9 0.1 8.1e-71 238.9 0.1 2.6 3 0 0 3 3 3 1 AAA domain AAA_12 PF13087.6 OAP61354.1 - 6.1e-61 205.5 0.0 2.3e-60 203.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 OAP61354.1 - 3.5e-09 36.7 0.1 1.7e-05 24.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 OAP61354.1 - 4e-07 30.5 0.0 1.3e-06 28.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 OAP61354.1 - 2.4e-05 24.2 0.1 0.065 13.0 0.0 3.3 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.21 OAP61354.1 - 4e-05 23.3 0.1 0.13 11.7 0.0 3.1 2 1 0 3 3 3 2 UvrD/REP helicase N-terminal domain AAA_23 PF13476.6 OAP61354.1 - 0.04 14.4 3.0 0.061 13.8 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_29 PF13555.6 OAP61354.1 - 0.053 13.3 0.3 0.12 12.1 0.3 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain zf-CCHC PF00098.23 OAP61354.1 - 0.15 12.2 20.7 0.44 10.7 3.3 3.5 3 0 0 3 3 3 0 Zinc knuckle Terminase_6 PF03237.15 OAP61354.1 - 0.15 11.7 1.0 3 7.4 0.4 2.7 2 0 0 2 2 2 0 Terminase-like family PhoLip_ATPase_C PF16212.5 OAP61355.1 - 1.7e-78 263.8 24.3 1.7e-78 263.8 24.3 2.5 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 OAP61355.1 - 4.1e-19 68.0 1.2 1e-18 66.8 1.2 1.7 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 OAP61355.1 - 4.9e-11 43.3 5.7 2e-07 31.5 1.0 3.3 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 OAP61355.1 - 7.3e-11 42.0 0.0 3.7e-10 39.8 0.0 2.1 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 OAP61355.1 - 0.00023 20.8 1.7 0.0013 18.3 0.0 2.8 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase_3 PF08282.12 OAP61355.1 - 0.026 14.3 0.4 0.051 13.3 0.4 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase ApbA PF02558.16 OAP61356.1 - 3e-28 98.4 0.0 4.4e-28 97.8 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 OAP61356.1 - 2.5e-21 76.2 0.0 3.8e-21 75.6 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal bZIP_1 PF00170.21 OAP61357.1 - 1.9e-08 34.3 5.6 3.2e-08 33.6 5.6 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 OAP61357.1 - 0.00069 20.1 5.7 0.0012 19.4 5.7 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor HALZ PF02183.18 OAP61357.1 - 0.00095 19.3 1.2 0.0019 18.4 1.2 1.5 1 0 0 1 1 1 1 Homeobox associated leucine zipper bZIP_2 PF07716.15 OAP61357.1 - 0.0013 18.8 9.2 0.0013 18.8 9.2 2.0 3 0 0 3 3 3 1 Basic region leucine zipper Myb_DNA-bind_3 PF12776.7 OAP61357.1 - 0.02 15.9 0.3 0.04 14.9 0.3 1.4 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain GAS PF13851.6 OAP61357.1 - 0.038 13.4 3.0 0.053 12.9 3.0 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding SOG2 PF10428.9 OAP61358.1 - 7e-99 332.3 0.1 7e-99 332.3 0.1 3.2 3 0 0 3 3 3 1 RAM signalling pathway protein LRR_8 PF13855.6 OAP61358.1 - 7.7e-12 44.8 1.1 2e-07 30.7 0.1 3.5 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 OAP61358.1 - 2.8e-10 40.3 1.6 0.00056 20.2 0.1 4.1 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 OAP61358.1 - 0.0095 15.9 2.2 4.1 7.7 0.0 4.6 5 0 0 5 5 5 1 Leucine Rich repeat LRR_1 PF00560.33 OAP61358.1 - 0.17 12.5 5.7 26 5.9 0.1 4.9 5 0 0 5 5 5 0 Leucine Rich Repeat zf-C2HC5 PF06221.13 OAP61359.1 - 1.9e-21 75.8 7.2 2.9e-21 75.2 7.2 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type Hexokinase_2 PF03727.16 OAP61360.1 - 3.6e-76 255.8 0.0 5.2e-76 255.2 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 OAP61360.1 - 1e-75 254.0 0.1 1.7e-75 253.3 0.1 1.3 1 0 0 1 1 1 1 Hexokinase 4HBT PF03061.22 OAP61362.1 - 0.047 14.0 0.1 0.87 10.0 0.0 2.5 2 0 0 2 2 2 0 Thioesterase superfamily DASH_Hsk3 PF08227.11 OAP61363.1 - 1.1e-21 76.9 3.4 1.6e-21 76.4 3.4 1.2 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like FlxA PF14282.6 OAP61363.1 - 0.022 14.7 0.3 0.031 14.3 0.3 1.2 1 0 0 1 1 1 0 FlxA-like protein DUF4349 PF14257.6 OAP61363.1 - 0.028 13.9 0.3 0.035 13.5 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) BBS2_C PF14782.6 OAP61363.1 - 0.079 11.7 0.0 0.094 11.5 0.0 1.1 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal RIC3 PF15361.6 OAP61363.1 - 0.088 13.2 0.1 0.12 12.8 0.1 1.2 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 NmrA PF05368.13 OAP61364.1 - 7.5e-10 38.8 0.0 9.2e-10 38.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAP61364.1 - 5.7e-05 23.1 0.0 9.8e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 OAP61364.1 - 0.0089 16.5 0.0 0.019 15.4 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain ADH_N PF08240.12 OAP61365.1 - 1e-30 105.8 0.4 2e-30 104.9 0.4 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAP61365.1 - 1e-22 80.5 2.3 1e-22 80.5 2.3 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAP61365.1 - 2.3e-07 31.9 0.4 6.6e-07 30.5 0.1 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase TrkA_N PF02254.18 OAP61365.1 - 0.00025 21.3 0.8 0.00093 19.4 0.5 2.0 2 0 0 2 2 2 1 TrkA-N domain MTS PF05175.14 OAP61365.1 - 0.0041 16.7 0.3 0.0077 15.8 0.3 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Shikimate_DH PF01488.20 OAP61365.1 - 0.0087 16.1 0.4 0.018 15.1 0.4 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Methyltransf_31 PF13847.6 OAP61365.1 - 0.13 12.0 0.1 0.25 11.1 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain DUF4911 PF16256.5 OAP61365.1 - 0.14 12.2 0.1 0.28 11.2 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4911) Sacchrp_dh_NADP PF03435.18 OAP61365.1 - 0.27 11.5 2.0 0.53 10.6 0.9 2.0 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain p450 PF00067.22 OAP61366.1 - 1.4e-67 228.4 0.0 1.7e-67 228.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Alpha-amylase PF00128.24 OAP61367.1 - 9.7e-28 97.7 0.4 2.3e-27 96.5 0.4 1.5 1 1 0 1 1 1 1 Alpha amylase, catalytic domain DUF1939 PF09154.10 OAP61367.1 - 1.9e-05 24.7 0.0 4.1e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1939) Alpha-amylase_C PF02806.18 OAP61367.1 - 2.6e-05 24.6 0.0 0.00056 20.3 0.0 2.3 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain Glyco_hydro_70 PF02324.16 OAP61367.1 - 0.00063 18.1 0.2 0.091 10.9 0.0 2.9 3 0 0 3 3 3 2 Glycosyl hydrolase family 70 SAM_PNT PF02198.16 OAP61367.1 - 0.47 10.5 2.6 0.37 10.8 0.3 1.9 2 0 0 2 2 2 0 Sterile alpha motif (SAM)/Pointed domain 4HBT PF03061.22 OAP61368.1 - 5.7e-08 33.0 0.4 9.1e-08 32.4 0.4 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 OAP61368.1 - 0.0012 19.2 0.9 0.015 15.5 0.4 2.0 1 1 1 2 2 2 1 Thioesterase-like superfamily MaoC_dehydratas PF01575.19 OAP61368.1 - 0.1 12.2 0.2 0.17 11.5 0.2 1.3 1 0 0 1 1 1 0 MaoC like domain p450 PF00067.22 OAP61369.1 - 8.5e-49 166.5 0.0 1.5e-48 165.7 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 CHAT PF12770.7 OAP61370.1 - 5.9e-36 124.4 0.2 1.1e-35 123.5 0.2 1.5 1 0 0 1 1 1 1 CHAT domain Abhydrolase_3 PF07859.13 OAP61371.1 - 0.0026 17.7 0.0 0.0046 16.8 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAP61371.1 - 0.075 12.3 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Orbi_VP5 PF00901.17 OAP61371.1 - 0.16 10.3 0.1 0.24 9.7 0.1 1.2 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 MFS_1 PF07690.16 OAP61372.1 - 2.4e-38 132.0 42.7 2.4e-38 132.0 42.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Zn_clus PF00172.18 OAP61373.1 - 4.4 7.5 14.4 27 5.0 14.4 2.4 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain NAD_binding_8 PF13450.6 OAP61374.1 - 6.7e-12 45.5 1.8 2e-11 43.9 1.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 OAP61374.1 - 2.2e-11 43.7 0.1 6.6e-11 42.2 0.0 1.7 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 OAP61374.1 - 1e-07 31.4 4.7 9.5e-07 28.2 4.7 2.1 1 1 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 OAP61374.1 - 2.5e-07 31.3 0.0 7.9e-07 29.7 0.0 1.9 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 OAP61374.1 - 0.00015 22.0 0.0 0.00031 21.0 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Thi4 PF01946.17 OAP61374.1 - 0.00037 19.8 0.2 0.00067 19.0 0.2 1.3 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 OAP61374.1 - 0.0011 18.6 3.0 0.0044 16.7 3.0 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 OAP61374.1 - 0.0026 17.0 0.8 0.0048 16.2 0.8 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 OAP61374.1 - 0.0088 15.3 0.3 0.016 14.5 0.3 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase MCRA PF06100.11 OAP61374.1 - 0.014 14.2 0.2 0.019 13.8 0.2 1.1 1 0 0 1 1 1 0 MCRA family HI0933_like PF03486.14 OAP61374.1 - 0.037 12.7 0.3 0.46 9.1 1.1 2.0 2 0 0 2 2 2 0 HI0933-like protein FAD_oxidored PF12831.7 OAP61374.1 - 0.037 13.4 1.6 0.056 12.8 1.6 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.22 OAP61374.1 - 0.33 10.0 1.4 0.52 9.3 1.4 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Promethin PF16015.5 OAP61375.1 - 8.1e-24 83.6 15.3 1.1e-23 83.2 15.3 1.1 1 0 0 1 1 1 1 Promethin DUF4212 PF13937.6 OAP61375.1 - 9.1 6.7 9.2 15 6.0 9.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4212) Catalase PF00199.19 OAP61376.1 - 4.3e-161 536.3 0.0 5.3e-161 536.0 0.0 1.1 1 0 0 1 1 1 1 Catalase Catalase_C PF18011.1 OAP61376.1 - 2.5e-42 144.1 0.0 4.2e-42 143.3 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain found in long catalases Catalase-rel PF06628.12 OAP61376.1 - 5.3e-18 65.0 0.0 1e-17 64.1 0.0 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive DUF4272 PF14094.6 OAP61376.1 - 0.067 12.4 0.0 0.37 10.0 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4272) Autophagy_N PF03986.13 OAP61377.1 - 1.8e-43 147.8 0.0 5.7e-43 146.1 0.0 1.9 2 1 0 2 2 2 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_C PF10381.9 OAP61377.1 - 5.9e-16 57.7 0.6 1e-15 56.9 0.6 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal Autophagy_act_C PF03987.15 OAP61377.1 - 3.1e-14 53.3 0.5 5.2e-14 52.6 0.5 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain ATG2_CAD PF13329.6 OAP61377.1 - 0.083 12.6 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Autophagy-related protein 2 CAD motif SNRNP27 PF08648.12 OAP61378.1 - 1.9e-06 27.8 0.1 4.7e-06 26.6 0.1 1.6 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins p450 PF00067.22 OAP61380.1 - 6.2e-47 160.4 0.0 8.4e-47 160.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_23 PF13489.6 OAP61381.1 - 2.2e-14 53.6 0.0 3.5e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAP61381.1 - 2.6e-14 53.3 0.0 3.4e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAP61381.1 - 1.8e-13 51.0 0.0 4e-13 49.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAP61381.1 - 2.8e-10 40.7 0.0 7.1e-10 39.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAP61381.1 - 1.1e-09 38.0 0.0 5.9e-09 35.6 0.0 1.9 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 OAP61381.1 - 7e-09 36.3 0.0 1.5e-08 35.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 OAP61381.1 - 5.5e-05 23.0 0.0 0.00019 21.2 0.0 1.8 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.19 OAP61381.1 - 0.00019 21.6 0.0 0.00028 21.0 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.14 OAP61381.1 - 0.0045 16.6 0.0 0.012 15.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain DUF2153 PF09921.9 OAP61382.1 - 0.039 13.8 0.4 0.07 12.9 0.4 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2153) CSN4_RPN5_eIF3a PF18420.1 OAP61383.1 - 0.027 14.6 0.9 0.89 9.8 0.0 2.7 2 0 0 2 2 2 0 CSN4/RPN5/eIF3a helix turn helix domain BAR PF03114.18 OAP61383.1 - 0.21 11.2 6.0 2.2 7.9 2.6 2.2 2 0 0 2 2 2 0 BAR domain Cyclin_N PF00134.23 OAP61384.1 - 1.5e-05 24.7 0.0 7.4e-05 22.5 0.0 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain TFIIB PF00382.19 OAP61384.1 - 0.0014 18.6 0.0 0.49 10.5 0.1 2.2 2 0 0 2 2 2 2 Transcription factor TFIIB repeat PNGaseA PF12222.8 OAP61385.1 - 4.5e-143 477.2 5.2 3.4e-142 474.3 5.2 1.9 1 1 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A Elong_Iki1 PF10483.9 OAP61386.1 - 9.9e-85 284.6 0.0 4e-84 282.6 0.0 1.7 1 1 0 1 1 1 1 Elongator subunit Iki1 Longin PF13774.6 OAP61387.1 - 1.7e-27 95.3 1.7 1.8e-27 95.2 0.8 1.5 2 0 0 2 2 2 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 OAP61387.1 - 4.9e-15 55.1 0.0 9.4e-15 54.2 0.0 1.5 1 0 0 1 1 1 1 Synaptobrevin SLM4 PF16818.5 OAP61387.1 - 0.0054 16.7 1.3 0.1 12.5 0.1 2.3 1 1 1 2 2 2 1 Protein SLM4 DUF3958 PF13125.6 OAP61387.1 - 0.037 14.2 0.9 1.2 9.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3958) DUF1664 PF07889.12 OAP61387.1 - 0.67 10.0 4.5 1.1 9.3 0.4 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) MIOX PF05153.15 OAP61388.1 - 7e-126 418.9 1.1 8.6e-126 418.6 1.1 1.1 1 0 0 1 1 1 1 Myo-inositol oxygenase HD PF01966.22 OAP61388.1 - 0.049 13.8 0.1 1.4 9.1 0.0 2.6 2 0 0 2 2 2 0 HD domain Aldo_ket_red PF00248.21 OAP61389.1 - 2.4e-43 148.4 0.0 2.6e-41 141.8 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family GFO_IDH_MocA PF01408.22 OAP61390.1 - 5.6e-24 85.3 0.4 1.3e-23 84.1 0.1 1.8 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 OAP61390.1 - 9.7e-06 25.6 0.0 1.9e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_2 PF03446.15 OAP61390.1 - 0.045 13.9 0.1 0.2 11.8 0.0 2.1 3 0 0 3 3 3 0 NAD binding domain of 6-phosphogluconate dehydrogenase SpdB PF05122.13 OAP61390.1 - 0.047 13.8 0.2 17 5.7 0.1 2.8 2 0 0 2 2 2 0 Mobile element transfer protein Gp_dh_N PF00044.24 OAP61390.1 - 0.069 13.5 0.0 0.28 11.6 0.0 2.0 1 1 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain HAD_2 PF13419.6 OAP61393.1 - 5.4e-18 65.7 0.0 8.3e-18 65.1 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Glyco_transf_8 PF01501.20 OAP61393.1 - 2.6e-16 60.0 0.2 4.7e-16 59.1 0.2 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 8 Hydrolase PF00702.26 OAP61393.1 - 3.5e-10 40.5 0.0 2.3e-09 37.8 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 OAP61393.1 - 0.00038 20.9 0.0 0.0011 19.3 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Nucleotid_trans PF03407.16 OAP61393.1 - 0.011 15.8 2.6 0.026 14.5 2.6 1.6 1 1 0 1 1 1 0 Nucleotide-diphospho-sugar transferase Hydrolase_like PF13242.6 OAP61393.1 - 0.012 15.6 0.0 0.024 14.7 0.0 1.5 1 0 0 1 1 1 0 HAD-hyrolase-like Mannosyl_trans3 PF11051.8 OAP61393.1 - 0.044 13.1 0.0 0.073 12.4 0.0 1.4 1 0 0 1 1 1 0 Mannosyltransferase putative CH PF00307.31 OAP61394.1 - 4e-47 158.9 0.1 1.8e-22 79.6 0.0 2.7 3 0 0 3 3 3 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 OAP61394.1 - 7.6e-11 41.7 0.3 3.6e-06 26.7 0.0 3.3 3 0 0 3 3 3 2 CAMSAP CH domain EF-hand_6 PF13405.6 OAP61394.1 - 7.9e-06 25.4 0.1 3.6e-05 23.3 0.1 2.2 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.32 OAP61394.1 - 0.00021 20.6 0.1 0.00084 18.7 0.0 2.2 2 0 0 2 2 2 1 EF hand EFhand_Ca_insen PF08726.10 OAP61394.1 - 0.0016 18.5 0.6 0.027 14.6 0.1 2.7 2 0 0 2 2 2 1 Ca2+ insensitive EF hand EF-hand_8 PF13833.6 OAP61394.1 - 0.0041 16.9 0.0 0.014 15.3 0.0 2.0 1 0 0 1 1 1 1 EF-hand domain pair DUF1943 PF09172.11 OAP61394.1 - 0.0057 15.9 0.2 0.0087 15.3 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1943) EF-hand_7 PF13499.6 OAP61394.1 - 0.038 14.4 1.7 0.18 12.2 0.2 2.8 2 1 0 2 2 2 0 EF-hand domain pair zf-RRPl_C4 PF17026.5 OAP61394.1 - 0.056 13.5 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type NADH-UOR_E PF16514.5 OAP61394.1 - 0.059 13.7 0.1 0.33 11.3 0.1 2.4 1 1 0 1 1 1 0 putative NADH-ubiquinone oxidoreductase chain E Spectrin PF00435.21 OAP61394.1 - 0.082 13.4 6.0 8.2 7.0 0.1 2.8 2 0 0 2 2 2 0 Spectrin repeat DUF4508 PF14969.6 OAP61394.1 - 0.15 12.3 3.2 5.6 7.3 0.4 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4508) FUSC PF04632.12 OAP61394.1 - 2.8 6.3 4.0 4.2 5.8 4.0 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family AMP-binding PF00501.28 OAP61395.1 - 9.9e-70 235.2 0.0 1.3e-69 234.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAP61395.1 - 9.7e-14 52.1 0.0 2.2e-13 51.0 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain FAD_binding_6 PF00970.24 OAP61396.1 - 5.5e-13 49.1 0.0 1.4e-12 47.8 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 OAP61396.1 - 1.7e-08 35.1 0.0 0.00045 20.8 0.0 2.6 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain Pyr_redox_2 PF07992.14 OAP61397.1 - 8.5e-48 163.1 2.2 9.2e-48 163.0 1.1 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAP61397.1 - 2e-18 66.7 7.3 7.5e-17 61.7 0.1 3.4 4 0 0 4 4 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 OAP61397.1 - 5.8e-16 58.7 0.0 1.5e-15 57.4 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_3 PF13738.6 OAP61397.1 - 2e-09 37.1 2.7 4.4e-06 26.2 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OAP61397.1 - 2.1e-09 37.0 3.8 3.8e-06 26.2 0.1 2.6 2 1 1 3 3 3 2 Glucose inhibited division protein A 3HCDH_N PF02737.18 OAP61397.1 - 3e-06 27.2 1.1 0.02 14.8 0.1 2.4 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 OAP61397.1 - 3.4e-06 27.4 1.8 0.031 14.7 0.1 3.0 2 1 0 2 2 2 2 Putative NAD(P)-binding Lycopene_cycl PF05834.12 OAP61397.1 - 1.3e-05 24.4 2.3 0.015 14.4 0.1 3.1 2 1 1 3 3 3 2 Lycopene cyclase protein FAD_binding_2 PF00890.24 OAP61397.1 - 3.9e-05 22.9 3.2 0.039 13.0 0.1 3.7 4 0 0 4 4 4 2 FAD binding domain 2-Hacid_dh_C PF02826.19 OAP61397.1 - 0.00013 21.3 0.7 0.17 11.2 0.0 3.7 4 0 0 4 4 4 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain K_oxygenase PF13434.6 OAP61397.1 - 0.00017 20.9 0.6 0.00093 18.4 0.1 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 OAP61397.1 - 0.00094 18.0 7.6 0.16 10.7 0.0 3.5 4 0 0 4 4 4 2 HI0933-like protein AlaDh_PNT_C PF01262.21 OAP61397.1 - 0.0015 17.9 1.4 0.035 13.4 0.1 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 OAP61397.1 - 0.0015 17.8 1.6 0.1 11.8 0.2 2.3 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 OAP61397.1 - 0.0022 17.4 4.8 0.025 13.9 0.7 2.9 2 1 1 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.17 OAP61397.1 - 0.0033 16.7 0.5 0.02 14.2 0.0 2.3 2 0 0 2 2 2 1 Thi4 family UDPG_MGDP_dh_N PF03721.14 OAP61397.1 - 0.034 13.7 0.1 2 7.9 0.0 2.5 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.18 OAP61397.1 - 0.046 14.0 5.1 4 7.7 0.2 3.1 3 0 0 3 3 2 0 TrkA-N domain XdhC_C PF13478.6 OAP61397.1 - 0.046 14.2 0.2 8.3 6.9 0.0 2.8 2 1 0 2 2 2 0 XdhC Rossmann domain ThiF PF00899.21 OAP61397.1 - 0.066 12.6 0.4 3.8 6.8 0.0 2.6 2 0 0 2 2 2 0 ThiF family DAO PF01266.24 OAP61397.1 - 0.097 12.2 9.0 1.1 8.8 0.3 3.3 3 1 0 3 3 3 0 FAD dependent oxidoreductase F420_oxidored PF03807.17 OAP61397.1 - 0.29 11.7 2.0 18 6.0 0.0 3.1 3 1 0 3 3 2 0 NADP oxidoreductase coenzyme F420-dependent MutL PF13941.6 OAP61399.1 - 0.032 12.8 0.0 0.053 12.1 0.0 1.3 1 0 0 1 1 1 0 MutL protein SrfB PF07520.11 OAP61399.1 - 0.1 10.5 0.0 0.16 9.9 0.0 1.2 1 0 0 1 1 1 0 Virulence factor SrfB EutA PF06277.11 OAP61399.1 - 0.22 10.3 0.5 3.1 6.5 0.1 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation protein EutA AA_permease_2 PF13520.6 OAP61401.1 - 1.4e-63 215.2 37.3 1.9e-63 214.8 37.3 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAP61401.1 - 5.4e-26 91.2 23.4 5.4e-26 91.2 23.4 2.1 2 0 0 2 2 2 1 Amino acid permease NADHdeh_related PF10125.9 OAP61401.1 - 0.0013 18.1 3.5 0.0031 16.9 3.5 1.6 1 0 0 1 1 1 1 NADH dehydrogenase I, subunit N related protein CCB1 PF12046.8 OAP61401.1 - 0.045 13.1 0.1 0.14 11.5 0.1 1.8 1 0 0 1 1 1 0 Cofactor assembly of complex C subunit B GFO_IDH_MocA PF01408.22 OAP61403.1 - 8.4e-23 81.5 0.0 1.4e-22 80.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 OAP61403.1 - 2.8e-14 53.1 0.0 5.3e-14 52.2 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 OAP61403.1 - 0.00077 20.1 0.1 0.0015 19.2 0.1 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Cyclin_C_2 PF16899.5 OAP61404.1 - 2.5e-32 111.3 0.2 1.2e-25 89.9 0.0 2.4 2 0 0 2 2 2 2 Cyclin C-terminal domain Cyclin_N PF00134.23 OAP61404.1 - 2e-06 27.6 0.0 4.7e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain UQ_con PF00179.26 OAP61405.1 - 9e-43 145.3 0.0 1.2e-42 144.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.10 OAP61405.1 - 0.00012 21.8 0.1 0.00022 21.0 0.1 1.4 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain GGA_N-GAT PF18308.1 OAP61405.1 - 0.006 16.2 0.1 0.013 15.1 0.1 1.5 1 0 0 1 1 1 1 GGA N-GAT domain Prok-E2_B PF14461.6 OAP61405.1 - 0.035 13.8 0.0 0.05 13.3 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B RWD PF05773.22 OAP61405.1 - 0.14 12.5 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 RWD domain UEV PF05743.13 OAP61405.1 - 0.17 11.7 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 UEV domain AAA PF00004.29 OAP61406.1 - 6.7e-41 139.8 0.0 1.2e-40 138.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OAP61406.1 - 1.4e-11 44.0 0.7 2.8e-11 43.0 0.7 1.5 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 OAP61406.1 - 1.3e-09 37.8 0.1 2.4e-09 37.0 0.1 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 OAP61406.1 - 5.1e-06 26.7 0.0 1.1e-05 25.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 OAP61406.1 - 5.3e-06 26.8 0.2 0.0059 16.9 0.2 2.6 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 OAP61406.1 - 1.3e-05 24.5 0.0 2.1e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 OAP61406.1 - 9.8e-05 22.4 0.1 0.00028 20.9 0.1 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OAP61406.1 - 0.00025 21.5 0.3 0.002 18.6 0.2 2.2 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 OAP61406.1 - 0.00026 20.8 0.0 0.00052 19.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 OAP61406.1 - 0.0028 18.2 0.0 0.0067 17.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 OAP61406.1 - 0.0034 17.6 0.0 0.0076 16.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.11 OAP61406.1 - 0.0098 15.8 0.0 0.041 13.8 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 OAP61406.1 - 0.012 15.7 0.0 0.027 14.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 OAP61406.1 - 0.016 14.9 0.0 0.04 13.7 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.13 OAP61406.1 - 0.018 14.3 0.1 0.058 12.6 0.1 1.6 1 1 0 1 1 1 0 TIP49 P-loop domain AAA_14 PF13173.6 OAP61406.1 - 0.018 15.1 0.0 0.037 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 OAP61406.1 - 0.021 14.2 0.1 0.57 9.5 0.1 2.2 1 1 0 2 2 2 0 KaiC NACHT PF05729.12 OAP61406.1 - 0.021 14.7 0.1 0.63 9.9 0.1 2.5 1 1 1 2 2 2 0 NACHT domain RNA_helicase PF00910.22 OAP61406.1 - 0.048 14.1 0.0 0.099 13.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.21 OAP61406.1 - 0.059 12.7 0.1 0.12 11.7 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 OAP61406.1 - 0.066 12.5 0.0 0.18 11.0 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin PhoH PF02562.16 OAP61406.1 - 0.087 12.3 0.3 0.51 9.7 0.1 2.0 2 0 0 2 2 2 0 PhoH-like protein Prot_ATP_OB_N PF17758.1 OAP61406.1 - 0.13 12.0 0.5 1 9.0 0.0 2.4 2 0 0 2 2 2 0 Proteasomal ATPase OB N-terminal domain AAA_25 PF13481.6 OAP61406.1 - 0.13 11.8 1.2 0.66 9.5 0.4 2.2 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.6 OAP61406.1 - 0.14 11.9 0.3 0.3 10.8 0.3 1.7 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.9 OAP61406.1 - 0.16 11.2 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 OAP61406.1 - 0.2 11.1 0.1 0.52 9.8 0.1 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region TRAM_LAG1_CLN8 PF03798.16 OAP61407.1 - 8.2e-47 159.5 21.2 8.2e-47 159.5 21.2 2.1 2 1 0 2 2 2 1 TLC domain TRAM1 PF08390.11 OAP61407.1 - 1e-19 69.9 0.5 2.9e-19 68.5 0.5 1.8 1 0 0 1 1 1 1 TRAM1-like protein FAM177 PF14774.6 OAP61407.1 - 0.1 12.9 1.2 2.5 8.5 0.1 2.7 2 0 0 2 2 2 0 FAM177 family Macoilin PF09726.9 OAP61407.1 - 6.1 5.3 6.4 11 4.5 6.4 1.3 1 0 0 1 1 1 0 Macoilin family WD40 PF00400.32 OAP61408.1 - 5e-27 93.6 12.2 2.1e-08 34.7 0.0 5.5 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAP61408.1 - 2.7e-09 37.2 0.6 0.0035 17.6 0.1 3.7 2 2 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OAP61408.1 - 0.00021 20.1 1.1 0.0022 16.7 0.0 2.3 3 0 0 3 3 3 1 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 OAP61408.1 - 0.00061 18.9 0.0 0.0073 15.3 0.0 2.4 3 0 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Me-amine-dh_H PF06433.11 OAP61408.1 - 0.00063 18.7 0.0 0.012 14.5 0.0 2.2 2 0 0 2 2 2 1 Methylamine dehydrogenase heavy chain (MADH) Proteasome_A_N PF10584.9 OAP61408.1 - 0.14 11.9 0.2 0.46 10.2 0.0 2.0 2 0 0 2 2 2 0 Proteasome subunit A N-terminal signature GAS PF13851.6 OAP61409.1 - 0.019 14.3 4.5 0.029 13.7 4.5 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Tropomyosin_1 PF12718.7 OAP61409.1 - 0.13 12.4 2.7 0.27 11.4 2.7 1.5 1 0 0 1 1 1 0 Tropomyosin like DUF2570 PF10828.8 OAP61409.1 - 0.29 11.0 5.1 0.49 10.2 5.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) PEP-utilisers_N PF05524.13 OAP61409.1 - 1.3 9.2 4.5 1.1e+02 3.0 4.5 2.4 1 1 0 1 1 1 0 PEP-utilising enzyme, N-terminal Trypan_PARP PF05887.11 OAP61409.1 - 2.5 8.1 15.0 4.6 7.2 4.3 2.8 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) CPSase_L_D2 PF02786.17 OAP61410.1 - 1e-75 253.9 0.0 1.8e-75 253.0 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.19 OAP61410.1 - 2e-38 130.8 0.0 4.9e-38 129.5 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_carb_N PF00289.22 OAP61410.1 - 6.5e-37 126.4 0.0 1.6e-36 125.2 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_lipoyl PF00364.22 OAP61410.1 - 3.3e-14 52.5 1.3 7.8e-14 51.3 1.3 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 OAP61410.1 - 1.5e-09 37.7 0.0 3.5e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 OAP61410.1 - 3.8e-08 33.1 0.0 7.4e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 OAP61410.1 - 0.0004 20.5 0.0 0.00074 19.6 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 OAP61410.1 - 0.00088 18.9 0.0 0.0056 16.3 0.0 2.3 2 1 0 2 2 2 1 RimK-like ATP-grasp domain GARS_A PF01071.19 OAP61410.1 - 0.00091 19.0 0.0 0.0016 18.3 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Biotin_lipoyl_2 PF13533.6 OAP61410.1 - 0.0018 18.0 0.4 0.032 14.0 0.0 2.5 1 1 1 2 2 2 1 Biotin-lipoyl like ATP-grasp_4 PF13535.6 OAP61410.1 - 0.039 13.5 0.0 0.088 12.4 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain ATPgrasp_ST PF14397.6 OAP61410.1 - 0.047 12.9 0.0 0.096 11.9 0.0 1.4 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp ATPgrasp_Ter PF15632.6 OAP61410.1 - 0.065 13.0 0.0 0.15 11.8 0.0 1.6 2 0 0 2 2 2 0 ATP-grasp in the biosynthetic pathway with Ter operon WW_FCH_linker PF16623.5 OAP61411.1 - 0.18 12.5 3.0 0.24 12.2 0.7 2.4 2 0 0 2 2 2 0 Unstructured linker region between on GAS7 protein PgpA PF04608.13 OAP61413.1 - 0.19 11.7 5.9 0.37 10.8 5.0 1.7 2 0 0 2 2 2 0 Phosphatidylglycerophosphatase A adh_short_C2 PF13561.6 OAP61414.1 - 2e-55 187.9 0.3 3.7e-55 187.0 0.3 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP61414.1 - 3.7e-38 130.9 1.0 8.6e-38 129.8 1.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAP61414.1 - 1.8e-13 50.8 0.3 2.5e-13 50.4 0.3 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAP61414.1 - 0.00015 21.3 0.0 0.0002 20.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAP61414.1 - 0.037 13.4 0.0 7 5.9 0.0 2.1 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase DUF1752 PF08550.10 OAP61415.1 - 0.0029 17.4 0.5 0.0029 17.4 0.5 1.8 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF1752) BSP_II PF05432.11 OAP61415.1 - 0.61 9.7 14.6 1.3 8.7 14.6 1.5 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) SAPS PF04499.15 OAP61415.1 - 1.1 7.9 7.1 1.7 7.3 7.1 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SURF2 PF05477.11 OAP61415.1 - 2.2 7.9 13.6 3.9 7.1 13.6 1.3 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) PHD PF00628.29 OAP61416.1 - 8.4e-10 38.4 1.9 8.4e-10 38.4 1.9 1.7 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.6 OAP61416.1 - 0.0038 16.8 2.5 0.0062 16.1 2.5 1.4 1 0 0 1 1 1 1 PHD-finger zf-CW PF07496.15 OAP61416.1 - 0.027 14.5 0.8 0.061 13.4 0.8 1.6 1 0 0 1 1 1 0 CW-type Zinc Finger UIM PF02809.20 OAP61416.1 - 0.035 14.0 4.2 0.084 12.8 4.2 1.7 1 0 0 1 1 1 0 Ubiquitin interaction motif zf-CSL PF05207.13 OAP61416.1 - 0.082 12.6 0.2 0.18 11.6 0.2 1.5 1 0 0 1 1 1 0 CSL zinc finger DUF3425 PF11905.8 OAP61417.1 - 3.9e-17 62.4 0.0 9.4e-17 61.2 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 OAP61417.1 - 0.025 14.7 7.0 0.047 13.8 7.0 1.4 1 0 0 1 1 1 0 bZIP transcription factor bZIP_2 PF07716.15 OAP61417.1 - 0.058 13.5 6.2 0.1 12.7 6.2 1.3 1 0 0 1 1 1 0 Basic region leucine zipper Ras PF00071.22 OAP61418.1 - 4.4e-24 84.9 0.0 5.2e-24 84.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Arf PF00025.21 OAP61418.1 - 0.027 13.9 0.0 0.034 13.6 0.0 1.2 1 0 0 1 1 1 0 ADP-ribosylation factor family Roc PF08477.13 OAP61418.1 - 0.18 12.0 0.0 0.27 11.4 0.0 1.3 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Carboxyl_trans PF01039.22 OAP61419.1 - 4.8e-140 467.5 0.1 6.4e-140 467.1 0.1 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain ECH_1 PF00378.20 OAP61419.1 - 0.092 12.0 1.1 0.13 11.5 0.0 1.8 2 0 0 2 2 2 0 Enoyl-CoA hydratase/isomerase HET PF06985.11 OAP61420.1 - 0.00063 20.1 0.0 0.0012 19.2 0.0 1.5 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MMR_HSR1 PF01926.23 OAP61421.1 - 1.3e-07 31.7 0.1 2.2e-07 30.9 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 OAP61421.1 - 1.4e-06 27.8 0.0 3.4e-06 26.5 0.0 1.6 1 1 0 1 1 1 1 AIG1 family FtsK_SpoIIIE PF01580.18 OAP61421.1 - 0.0056 16.1 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family RsgA_GTPase PF03193.16 OAP61421.1 - 0.011 15.7 0.1 0.039 13.9 0.1 1.9 1 1 0 1 1 1 0 RsgA GTPase Peptidase_S9 PF00326.21 OAP61421.1 - 0.017 14.6 0.0 0.032 13.7 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Dynamin_N PF00350.23 OAP61421.1 - 0.019 15.1 1.2 1.1 9.3 0.0 2.4 1 1 1 2 2 2 0 Dynamin family SRPRB PF09439.10 OAP61421.1 - 0.021 14.2 0.0 0.04 13.3 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_18 PF13238.6 OAP61421.1 - 0.033 14.7 0.0 0.17 12.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 OAP61421.1 - 0.04 13.6 0.0 0.068 12.9 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DUF87 PF01935.17 OAP61421.1 - 0.072 13.2 0.3 0.16 12.1 0.3 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_29 PF13555.6 OAP61421.1 - 0.078 12.7 0.2 0.22 11.3 0.2 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 OAP61421.1 - 0.089 13.1 0.0 0.26 11.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 OAP61421.1 - 0.092 11.9 0.0 0.19 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Septin PF00735.18 OAP61421.1 - 0.11 11.8 0.0 0.23 10.7 0.0 1.5 1 0 0 1 1 1 0 Septin NTPase_P4 PF11602.8 OAP61421.1 - 0.12 11.5 0.0 0.94 8.6 0.0 2.0 2 0 0 2 2 2 0 ATPase P4 of dsRNA bacteriophage phi-12 Cupin_2 PF07883.11 OAP61422.1 - 7.2e-07 28.8 0.0 1.2e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 OAP61422.1 - 0.12 12.1 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Pro_isomerase PF00160.21 OAP61424.1 - 2.3e-54 184.0 0.0 2.6e-54 183.8 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD NAD_binding_6 PF08030.12 OAP61425.1 - 3.4e-20 72.7 0.0 2.2e-19 70.1 0.0 2.0 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 OAP61425.1 - 1.7e-18 66.9 11.7 1.7e-18 66.9 11.7 2.7 3 0 0 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 OAP61425.1 - 1.2e-12 47.9 0.0 2.8e-12 46.7 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 OAP61425.1 - 1.1e-05 26.0 0.0 0.097 13.3 0.0 2.3 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain DUF4405 PF14358.6 OAP61425.1 - 2.1 9.0 21.9 15 6.2 10.9 3.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4405) POP1 PF06978.11 OAP61426.1 - 1.5e-69 234.1 22.8 1.5e-69 234.1 22.8 2.8 3 0 0 3 3 3 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 OAP61426.1 - 1.8e-28 98.7 1.4 8.7e-28 96.5 0.5 2.7 2 0 0 2 2 2 1 POPLD (NUC188) domain DUF563 PF04577.14 OAP61426.1 - 2.8 8.0 4.7 0.76 9.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF563) Fungal_trans_2 PF11951.8 OAP61427.1 - 7.9e-14 51.3 0.0 1.3e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain bZIP_1 PF00170.21 OAP61428.1 - 3.2e-06 27.1 11.5 5.3e-06 26.4 9.3 2.0 1 1 1 2 2 2 1 bZIP transcription factor CEP63 PF17045.5 OAP61428.1 - 0.0033 17.4 1.5 0.0045 16.9 1.5 1.1 1 0 0 1 1 1 1 Centrosomal protein of 63 kDa bZIP_2 PF07716.15 OAP61428.1 - 0.0075 16.3 12.5 0.025 14.7 6.7 2.3 1 1 1 2 2 2 1 Basic region leucine zipper DUF4094 PF13334.6 OAP61428.1 - 0.013 15.9 2.4 0.021 15.2 2.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4094) Macoilin PF09726.9 OAP61428.1 - 0.028 13.0 0.1 0.032 12.8 0.1 1.1 1 0 0 1 1 1 0 Macoilin family CLZ PF16526.5 OAP61428.1 - 0.069 13.5 2.6 0.21 12.0 1.8 2.1 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels FlxA PF14282.6 OAP61428.1 - 0.091 12.8 1.2 0.42 10.6 1.1 2.0 1 1 0 1 1 1 0 FlxA-like protein SlyX PF04102.12 OAP61428.1 - 0.1 13.2 1.7 0.39 11.4 1.4 2.1 1 1 1 2 2 2 0 SlyX DUF2390 PF09523.10 OAP61428.1 - 0.12 12.7 1.4 0.25 11.7 1.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2390) SHE3 PF17078.5 OAP61428.1 - 0.12 12.1 3.0 0.19 11.4 3.0 1.2 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 ABC_tran_CTD PF16326.5 OAP61428.1 - 0.18 12.0 2.1 0.36 11.1 2.1 1.5 1 0 0 1 1 1 0 ABC transporter C-terminal domain GIT_CC PF16559.5 OAP61428.1 - 0.19 11.6 1.0 0.31 10.9 1.0 1.3 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor LapA_dom PF06305.11 OAP61428.1 - 6.1 6.7 6.9 4.6 7.1 0.1 2.3 2 1 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Redoxin PF08534.10 OAP61429.1 - 3.6e-33 114.4 0.0 4.1e-33 114.2 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 OAP61429.1 - 1.3e-10 41.2 0.0 1.8e-10 40.8 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family DUF1348 PF07080.11 OAP61430.1 - 5.2e-54 181.6 2.4 6.6e-54 181.3 2.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) SnoaL_2 PF12680.7 OAP61430.1 - 0.00032 21.3 0.0 0.0008 20.0 0.0 1.8 1 1 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 OAP61430.1 - 0.00075 19.9 0.0 0.0012 19.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) Fasciclin PF02469.22 OAP61431.1 - 7.8e-45 152.2 0.0 3.8e-23 82.1 0.0 2.2 2 0 0 2 2 2 2 Fasciclin domain Pkinase PF00069.25 OAP61432.1 - 3.5e-68 229.8 0.0 2.9e-67 226.8 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP61432.1 - 1.2e-36 126.4 0.0 6.2e-34 117.5 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Fungal_KA1 PF16797.5 OAP61432.1 - 3.7e-36 123.4 0.1 8.6e-36 122.2 0.1 1.7 1 0 0 1 1 1 1 Fungal kinase associated-1 domain Haspin_kinase PF12330.8 OAP61432.1 - 0.00012 21.1 0.1 0.00032 19.8 0.0 1.7 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 OAP61432.1 - 0.0092 15.9 1.1 0.047 13.6 0.1 2.4 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.6 OAP61432.1 - 0.016 14.5 0.0 0.03 13.7 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 OAP61432.1 - 0.018 14.4 0.0 0.035 13.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 OAP61432.1 - 0.066 12.8 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase HET PF06985.11 OAP61433.1 - 1.1e-25 90.7 0.0 2.5e-25 89.5 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) FMO-like PF00743.19 OAP61434.1 - 4.6e-36 124.3 0.0 5.6e-24 84.5 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OAP61434.1 - 5.7e-12 45.5 0.7 2e-10 40.4 0.2 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAP61434.1 - 1.9e-09 37.2 0.0 2.1e-08 33.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAP61434.1 - 7.6e-08 31.9 0.0 1.5e-05 24.3 0.0 2.7 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 OAP61434.1 - 8.8e-05 22.5 0.0 0.0014 18.6 0.0 2.4 1 1 0 1 1 1 1 FAD-NAD(P)-binding DAO PF01266.24 OAP61434.1 - 0.0004 20.1 0.4 0.12 11.9 0.0 2.8 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAP61434.1 - 0.00046 20.4 0.0 0.0011 19.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 OAP61434.1 - 0.11 13.1 0.2 0.8 10.3 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF1690 PF07956.11 OAP61435.1 - 3.5e-41 140.9 6.0 4.2e-41 140.6 6.0 1.1 1 0 0 1 1 1 1 Protein of Unknown function (DUF1690) MutS_II PF05188.17 OAP61435.1 - 0.0037 17.5 0.3 0.0084 16.4 0.1 1.6 1 1 0 1 1 1 1 MutS domain II Rootletin PF15035.6 OAP61435.1 - 0.0053 16.8 4.7 0.0097 15.9 0.9 2.0 2 0 0 2 2 2 1 Ciliary rootlet component, centrosome cohesion DUF4633 PF15464.6 OAP61435.1 - 0.062 13.4 2.8 0.15 12.2 0.8 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4633) Apolipoprotein PF01442.18 OAP61435.1 - 0.12 12.2 8.5 0.25 11.2 8.5 1.5 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain T6PP_N PF18572.1 OAP61435.1 - 0.13 12.2 1.5 0.28 11.0 1.3 1.8 1 1 0 1 1 1 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain Acetyltransf_1 PF00583.25 OAP61436.1 - 2.3e-08 34.3 0.0 3.3e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OAP61436.1 - 4.1e-05 23.9 0.0 6.8e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OAP61436.1 - 0.0016 18.4 0.0 0.0028 17.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAP61436.1 - 0.0029 17.6 0.0 0.0062 16.5 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Methyltransf_2 PF00891.18 OAP61438.1 - 1.5e-26 93.0 0.0 2.4e-26 92.4 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_23 PF13489.6 OAP61438.1 - 0.053 13.3 0.0 0.22 11.3 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Dimerisation2 PF16864.5 OAP61438.1 - 0.068 13.2 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Dimerisation domain Methyltransf_23 PF13489.6 OAP61439.1 - 3.9e-21 75.6 0.0 1.2e-20 74.1 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAP61439.1 - 3.2e-14 53.4 0.0 1.4e-13 51.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAP61439.1 - 4.6e-13 49.6 0.0 1.1e-12 48.4 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAP61439.1 - 1.1e-11 44.7 0.0 7.7e-11 42.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAP61439.1 - 6.4e-09 36.5 0.0 3.9e-08 34.0 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 OAP61439.1 - 4.1e-05 23.1 0.0 6e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 OAP61439.1 - 0.0002 21.0 0.0 0.00073 19.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.18 OAP61439.1 - 0.00051 19.4 0.0 0.00086 18.7 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_4 PF02390.17 OAP61439.1 - 0.0045 16.5 0.0 0.017 14.6 0.0 1.9 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_16 PF10294.9 OAP61439.1 - 0.024 14.4 0.0 0.039 13.7 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Ubie_methyltran PF01209.18 OAP61439.1 - 0.11 11.8 0.0 0.29 10.4 0.0 1.7 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family CMAS PF02353.20 OAP61439.1 - 0.11 11.8 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Peptidase_S28 PF05577.12 OAP61440.1 - 3.9e-33 114.9 0.0 5.8e-33 114.3 0.0 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S9 PF00326.21 OAP61440.1 - 7.4e-05 22.3 0.0 0.0069 15.9 0.0 2.6 2 0 0 2 2 2 2 Prolyl oligopeptidase family GDPD PF03009.17 OAP61441.1 - 3.3e-13 49.9 0.0 4.1e-13 49.6 0.0 1.1 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family CorA PF01544.18 OAP61442.1 - 0.0036 16.7 1.0 0.0053 16.1 0.2 1.7 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein Sugar_tr PF00083.24 OAP61443.1 - 1.7e-48 165.6 12.3 3.5e-48 164.6 12.3 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP61443.1 - 4.8e-20 71.8 19.8 8.8e-20 70.9 19.5 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily CMAS PF02353.20 OAP61444.1 - 1.9e-60 204.5 0.0 2.3e-60 204.2 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 OAP61444.1 - 1.3e-09 38.1 0.0 2.3e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAP61444.1 - 5.9e-06 26.9 0.0 1.3e-05 25.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAP61444.1 - 1.3e-05 25.8 0.0 2.7e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 OAP61444.1 - 0.0057 16.2 0.0 0.01 15.4 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_12 PF08242.12 OAP61444.1 - 0.011 16.4 0.1 0.057 14.2 0.1 2.1 1 1 0 1 1 1 0 Methyltransferase domain EXS PF03124.14 OAP61445.1 - 6e-114 380.8 11.5 6.8e-114 380.6 11.5 1.0 1 0 0 1 1 1 1 EXS family Sugar_tr PF00083.24 OAP61446.1 - 2.8e-38 132.0 31.0 2e-35 122.5 31.0 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP61446.1 - 3.7e-24 85.3 32.8 1.8e-12 46.9 13.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 OAP61446.1 - 0.0094 14.6 20.0 0.13 10.8 7.3 3.2 1 1 2 3 3 3 2 MFS/sugar transport protein PhyH PF05721.13 OAP61447.1 - 8.8e-25 88.2 0.0 1.4e-24 87.6 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) HD PF01966.22 OAP61447.1 - 1.2e-07 31.9 0.0 1.2e-06 28.7 0.0 2.3 2 0 0 2 2 2 1 HD domain 2OG-FeII_Oxy_5 PF13759.6 OAP61447.1 - 0.0011 19.3 0.0 0.0025 18.2 0.0 1.6 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase HD_4 PF13328.6 OAP61447.1 - 0.0064 16.2 0.0 0.014 15.1 0.0 1.6 1 0 0 1 1 1 1 HD domain HDOD PF08668.12 OAP61447.1 - 0.012 15.1 0.0 0.023 14.2 0.0 1.3 1 0 0 1 1 1 0 HDOD domain 2OG-FeII_Oxy_3 PF13640.6 OAP61447.1 - 0.047 14.6 0.0 0.092 13.6 0.0 1.4 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily CRAL_TRIO PF00650.20 OAP61448.1 - 6.1e-19 68.3 0.0 7.7e-19 68.0 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 OAP61448.1 - 2.4e-07 30.8 0.1 6.2e-07 29.5 0.1 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Ribosomal_S16 PF00886.19 OAP61449.1 - 6.3e-23 80.6 0.0 1.3e-22 79.7 0.0 1.5 1 1 0 1 1 1 1 Ribosomal protein S16 YjeF_N PF03853.15 OAP61450.1 - 7.8e-35 120.3 0.0 9.6e-35 120.0 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus DnaJ_C PF01556.18 OAP61451.1 - 1.2e-37 129.2 1.1 1.6e-37 128.9 1.1 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 OAP61451.1 - 3.5e-28 97.5 3.4 5.8e-28 96.8 3.4 1.4 1 0 0 1 1 1 1 DnaJ domain Fungal_trans_2 PF11951.8 OAP61452.1 - 9.5e-07 28.0 0.4 1.5e-06 27.3 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain EMC1_C PF07774.13 OAP61453.1 - 2.2e-70 236.7 0.0 4.8e-70 235.6 0.0 1.6 2 0 0 2 2 2 1 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 OAP61453.1 - 4.8e-16 59.1 12.8 7.6e-10 38.8 4.6 3.4 1 1 0 3 3 3 2 PQQ-like domain PQQ PF01011.21 OAP61453.1 - 0.0033 17.3 4.3 2.3 8.3 0.0 5.1 5 0 0 5 5 5 1 PQQ enzyme repeat PQQ_3 PF13570.6 OAP61453.1 - 0.0076 16.7 13.1 1.4 9.5 0.1 6.6 6 0 0 6 6 6 1 PQQ-like domain Germane PF10646.9 OAP61453.1 - 0.11 13.3 0.1 0.43 11.4 0.1 2.0 2 0 0 2 2 2 0 Sporulation and spore germination PUL PF08324.11 OAP61454.1 - 1.4e-48 165.6 0.1 1.8e-48 165.2 0.1 1.2 1 0 0 1 1 1 1 PUL domain PFU PF09070.11 OAP61454.1 - 1.2e-43 147.9 0.6 2.3e-43 147.0 0.6 1.5 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.32 OAP61454.1 - 2.5e-26 91.4 10.3 1e-05 26.2 0.0 6.8 6 0 0 6 6 6 6 WD domain, G-beta repeat Zn_clus PF00172.18 OAP61455.1 - 3.3e-07 30.3 7.2 7.5e-07 29.2 7.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Exo_endo_phos PF03372.23 OAP61456.1 - 6.7e-05 22.5 1.8 0.00018 21.1 1.8 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family ERG2_Sigma1R PF04622.12 OAP61457.1 - 8.7e-90 299.6 0.0 1e-89 299.4 0.0 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein 3Beta_HSD PF01073.19 OAP61458.1 - 4.9e-28 97.9 0.0 1.7e-27 96.2 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 OAP61458.1 - 8.8e-14 51.5 0.0 2.1e-13 50.3 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 OAP61458.1 - 6.9e-09 35.2 0.0 2.9e-08 33.2 0.0 1.8 2 0 0 2 2 2 1 Male sterility protein KR PF08659.10 OAP61458.1 - 1.5e-06 28.3 0.0 3.2e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 OAP61458.1 - 4.2e-06 26.4 0.0 3e-05 23.6 0.0 2.3 3 0 0 3 3 3 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 OAP61458.1 - 5.6e-06 25.7 0.0 2.2e-05 23.7 0.0 1.8 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 OAP61458.1 - 6.7e-05 22.9 0.0 0.00013 21.9 0.0 1.6 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 OAP61458.1 - 0.00037 19.7 0.0 0.0042 16.2 0.0 2.0 2 0 0 2 2 2 1 RmlD substrate binding domain DUF3712 PF12505.8 OAP61459.1 - 9.2e-23 80.9 0.0 1.9e-22 79.8 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3712) CoA_transf_3 PF02515.17 OAP61461.1 - 3e-44 151.6 0.1 9.3e-39 133.6 0.0 2.2 2 0 0 2 2 2 2 CoA-transferase family III An_peroxidase PF03098.15 OAP61462.1 - 9.7e-35 120.1 0.0 1.5e-18 66.7 0.0 3.4 1 1 2 3 3 3 3 Animal haem peroxidase p450 PF00067.22 OAP61462.1 - 0.00024 20.0 0.0 0.00052 18.9 0.0 1.5 1 0 0 1 1 1 1 Cytochrome P450 DUF2235 PF09994.9 OAP61463.1 - 2.5e-95 319.1 1.1 3.6e-95 318.6 1.1 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) DUF4337 PF14235.6 OAP61463.1 - 1.5 8.9 4.3 0.85 9.7 0.4 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4337) DPM3 PF08285.11 OAP61464.1 - 0.025 14.7 0.0 0.068 13.4 0.0 1.7 1 0 0 1 1 1 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF4203 PF13886.6 OAP61465.1 - 1.3e-49 168.6 30.2 1.6e-49 168.3 30.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) Pept_tRNA_hydro PF01195.19 OAP61467.1 - 2.8e-29 102.2 0.0 3.9e-29 101.8 0.0 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase MFS_1 PF07690.16 OAP61468.1 - 6.6e-24 84.5 28.7 1.3e-23 83.6 27.7 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_transf_15 PF01793.16 OAP61469.1 - 4.9e-111 371.1 9.8 6e-111 370.8 9.8 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Voldacs PF03517.13 OAP61470.1 - 1.4e-27 96.5 0.9 2.8e-27 95.6 0.0 1.9 2 0 0 2 2 2 1 Regulator of volume decrease after cellular swelling GCP_N_terminal PF17681.1 OAP61471.1 - 2.1e-26 93.3 1.4 6.8e-26 91.6 0.1 2.1 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 OAP61471.1 - 5.8e-20 72.0 3.2 1.1e-19 71.1 3.2 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP5-Mod21 PF14609.6 OAP61471.1 - 0.0098 14.3 4.3 0.055 11.8 1.6 2.8 2 1 0 2 2 2 1 gamma-Tubulin ring complex non-core subunit mod21 Abhydrolase_2 PF02230.16 OAP61473.1 - 4.1e-15 56.2 0.0 5.2e-15 55.8 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Esterase PF00756.20 OAP61473.1 - 0.013 15.2 0.0 0.018 14.7 0.0 1.4 1 1 0 1 1 1 0 Putative esterase Abhydrolase_6 PF12697.7 OAP61473.1 - 0.025 15.2 0.5 0.04 14.5 0.5 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF3759 PF12585.8 OAP61474.1 - 1.7e-40 136.9 6.9 2.1e-40 136.6 6.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) XRCC4 PF06632.12 OAP61475.1 - 6.8e-17 61.3 12.6 1.1e-16 60.7 12.6 1.2 1 0 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 CCDC-167 PF15188.6 OAP61475.1 - 0.28 11.5 10.4 0.1 12.9 3.1 3.3 2 1 1 3 3 3 0 Coiled-coil domain-containing protein 167 FAM76 PF16046.5 OAP61475.1 - 0.36 10.1 14.7 0.014 14.8 8.3 1.7 2 0 0 2 2 2 0 FAM76 protein TMPIT PF07851.13 OAP61475.1 - 0.51 9.5 2.6 0.77 8.9 2.6 1.2 1 0 0 1 1 1 0 TMPIT-like protein NPV_P10 PF05531.12 OAP61475.1 - 0.62 10.6 7.0 0.46 11.0 3.6 2.3 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein AP_endonuc_2 PF01261.24 OAP61477.1 - 2.8e-30 105.3 0.1 5.4e-30 104.4 0.0 1.5 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel Glyco_hydro_43 PF04616.14 OAP61478.1 - 2.4e-23 82.9 0.1 3e-23 82.5 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.20 OAP61478.1 - 0.019 14.6 0.0 0.11 12.1 0.0 1.8 1 1 1 2 2 2 0 Glycosyl hydrolases family 32 N-terminal domain SH3_5 PF08460.10 OAP61478.1 - 0.11 12.5 0.7 32 4.7 0.0 3.2 3 0 0 3 3 3 0 Bacterial SH3 domain Alk_phosphatase PF00245.20 OAP61479.1 - 1.4e-73 248.2 0.1 2e-72 244.4 0.1 2.0 1 1 0 1 1 1 1 Alkaline phosphatase Sulfatase PF00884.23 OAP61479.1 - 1.5e-07 31.1 0.3 5.5e-07 29.3 0.3 1.8 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 OAP61479.1 - 5.6e-06 26.2 0.1 9.5e-06 25.4 0.1 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 OAP61479.1 - 0.0042 15.7 0.2 0.0062 15.2 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Metalloenzyme PF01676.18 OAP61479.1 - 0.041 13.2 0.1 0.078 12.3 0.1 1.4 1 0 0 1 1 1 0 Metalloenzyme superfamily DUF1398 PF07166.11 OAP61480.1 - 3.9e-06 26.9 0.0 0.00014 21.9 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1398) HET PF06985.11 OAP61481.1 - 0.0044 17.4 0.5 0.017 15.4 0.1 2.2 1 1 1 2 2 2 1 Heterokaryon incompatibility protein (HET) GP67 PF17634.2 OAP61484.1 - 1.9 8.9 6.0 6.2 7.3 6.0 1.8 1 0 0 1 1 1 0 Gene product 67 DUF3425 PF11905.8 OAP61486.1 - 8e-18 64.6 0.4 8e-18 64.6 0.4 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3425) MAS20 PF02064.15 OAP61486.1 - 0.94 9.6 3.7 1.6 8.8 3.7 1.3 1 0 0 1 1 1 0 MAS20 protein import receptor OrfB_IS605 PF01385.19 OAP61486.1 - 8.7 6.6 7.1 4.9 7.4 4.9 1.7 2 0 0 2 2 2 0 Probable transposase Abhydrolase_6 PF12697.7 OAP61488.1 - 9.9e-07 29.6 0.3 1.6e-06 28.9 0.3 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAP61488.1 - 0.015 14.9 0.0 0.026 14.2 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAP61488.1 - 0.018 14.3 0.0 0.074 12.3 0.0 1.9 1 1 0 1 1 1 0 Serine aminopeptidase, S33 BAAT_C PF08840.11 OAP61488.1 - 0.047 13.6 0.0 0.081 12.8 0.0 1.4 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Acetate_kinase PF00871.17 OAP61489.1 - 1.4e-95 320.3 0.2 1.6e-95 320.1 0.2 1.0 1 0 0 1 1 1 1 Acetokinase family XFP_N PF09364.10 OAP61490.1 - 4.4e-102 341.6 0.1 5.5e-102 341.3 0.1 1.0 1 0 0 1 1 1 1 XFP N-terminal domain TPP_enzyme_C PF02775.21 OAP61490.1 - 0.029 14.2 0.1 0.047 13.5 0.1 1.3 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain XFP_C PF09363.10 OAP61491.1 - 5.1e-80 267.7 0.0 7e-80 267.3 0.0 1.2 1 0 0 1 1 1 1 XFP C-terminal domain XFP PF03894.15 OAP61491.1 - 5.5e-78 260.7 0.0 8.4e-78 260.1 0.0 1.3 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase XFP_N PF09364.10 OAP61491.1 - 1.4e-42 145.8 0.0 1.9e-42 145.4 0.0 1.2 1 0 0 1 1 1 1 XFP N-terminal domain Transketolase_C PF02780.20 OAP61491.1 - 0.021 14.7 0.2 0.15 12.0 0.1 2.2 2 0 0 2 2 2 0 Transketolase, C-terminal domain SH3_9 PF14604.6 OAP61491.1 - 0.041 13.7 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Variant SH3 domain SH3_2 PF07653.17 OAP61491.1 - 0.15 11.7 0.0 0.4 10.4 0.0 1.6 1 0 0 1 1 1 0 Variant SH3 domain MFS_1 PF07690.16 OAP61493.1 - 2.2e-33 115.6 37.8 7.8e-33 113.8 25.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 OAP61493.1 - 6.2e-06 24.9 1.1 6.2e-06 24.9 1.1 2.4 3 0 0 3 3 3 2 Fungal trichothecene efflux pump (TRI12) CHCH PF06747.13 OAP61494.1 - 6.5e-11 42.1 6.6 2.2e-08 34.0 2.1 2.4 2 0 0 2 2 2 2 CHCH domain CX9C PF16860.5 OAP61494.1 - 0.0001 22.2 3.7 0.0028 17.6 1.0 2.2 2 0 0 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Cmc1 PF08583.10 OAP61494.1 - 0.027 14.5 8.2 0.54 10.3 2.0 2.2 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.9 OAP61494.1 - 0.21 11.9 6.8 6.3 7.2 2.1 2.9 2 1 1 3 3 3 0 Cytochrome c oxidase assembly protein PET191 UCR_hinge PF02320.16 OAP61494.1 - 1.2 9.4 6.5 9.1 6.6 5.6 2.5 1 1 1 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein DUF2959 PF11172.8 OAP61495.1 - 0.072 13.2 0.0 0.1 12.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2959) RHD3 PF05879.12 OAP61496.1 - 0 1038.2 0.0 0 1037.8 0.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.19 OAP61496.1 - 1.1e-06 28.2 0.2 1.8e-06 27.4 0.2 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.23 OAP61496.1 - 3.1e-06 27.4 0.1 8.7e-06 25.9 0.0 1.8 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 OAP61496.1 - 1.9e-05 24.7 0.0 3.9e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.6 OAP61496.1 - 0.00013 22.3 0.0 0.00041 20.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain Septin PF00735.18 OAP61496.1 - 0.012 15.0 0.1 0.022 14.0 0.1 1.4 1 0 0 1 1 1 0 Septin Peptidase_M18 PF02127.15 OAP61497.1 - 6.4e-136 453.6 0.0 7.4e-136 453.4 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Drc1-Sld2 PF11719.8 OAP61498.1 - 0.11 12.0 0.1 0.17 11.4 0.1 1.3 1 0 0 1 1 1 0 DNA replication and checkpoint protein MFS_1 PF07690.16 OAP61499.1 - 3.3e-33 115.1 36.8 3.3e-33 115.1 36.8 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily NmrA PF05368.13 OAP61500.1 - 7.8e-39 133.6 0.0 9.6e-39 133.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAP61500.1 - 9e-13 48.5 0.0 1.2e-12 48.1 0.0 1.3 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAP61500.1 - 1.7e-06 27.7 0.0 2.3e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OAP61500.1 - 0.0028 16.7 0.0 0.0037 16.3 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 OAP61500.1 - 0.016 15.2 0.1 0.024 14.6 0.1 1.2 1 0 0 1 1 1 0 KR domain DXP_reductoisom PF02670.16 OAP61500.1 - 0.11 13.2 0.0 0.18 12.5 0.0 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase TrkA_N PF02254.18 OAP61500.1 - 0.11 12.8 0.0 0.19 12.0 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain UQ_con PF00179.26 OAP61501.1 - 5.6e-51 171.9 0.0 6.3e-51 171.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OAP61501.1 - 0.17 11.6 0.0 0.4 10.4 0.0 1.5 1 1 0 1 1 1 0 Prokaryotic E2 family B TP6A_N PF04406.14 OAP61502.1 - 1.4e-21 76.3 0.4 2.6e-21 75.4 0.4 1.5 1 0 0 1 1 1 1 Type IIB DNA topoisomerase SQHop_cyclase_C PF13243.6 OAP61503.1 - 7.4e-57 192.9 0.3 1.5e-52 178.7 0.4 2.2 2 0 0 2 2 2 2 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 OAP61503.1 - 7.1e-45 153.3 3.6 7.1e-38 130.3 0.5 3.7 3 1 1 4 4 4 3 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.21 OAP61503.1 - 5.7e-35 118.7 1.2 1.6e-12 47.0 0.0 5.1 5 0 0 5 5 5 3 Prenyltransferase and squalene oxidase repeat TED_complement PF07678.14 OAP61503.1 - 1.7e-05 24.1 0.5 0.0019 17.3 0.1 3.3 1 1 2 3 3 3 2 A-macroglobulin TED domain Pec_lyase PF09492.10 OAP61503.1 - 0.091 12.1 0.1 5.7 6.2 0.0 3.4 3 1 1 4 4 4 0 Pectic acid lyase FAD_binding_3 PF01494.19 OAP61504.1 - 2.4e-07 30.3 1.6 7.5e-06 25.4 1.6 2.5 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 OAP61504.1 - 0.00027 20.3 0.3 3.5e+02 0.2 0.0 1.9 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OAP61504.1 - 0.0025 16.9 0.0 0.0056 15.8 0.0 1.5 1 1 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 OAP61504.1 - 0.004 16.4 0.2 0.0068 15.7 0.2 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 OAP61504.1 - 0.0057 16.9 0.1 0.0057 16.9 0.1 2.4 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 OAP61504.1 - 0.0065 15.2 1.7 0.012 14.3 0.3 2.1 3 0 0 3 3 3 1 HI0933-like protein DAO PF01266.24 OAP61504.1 - 0.011 15.4 1.8 0.022 14.3 1.8 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 OAP61504.1 - 0.051 14.1 0.2 0.17 12.4 0.1 1.9 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 OAP61504.1 - 0.058 12.7 0.3 0.33 10.2 0.0 2.2 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 OAP61504.1 - 0.059 12.6 0.4 0.085 12.1 0.4 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAP61504.1 - 0.061 13.3 0.3 0.78 9.7 0.3 2.5 1 1 0 1 1 1 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 OAP61504.1 - 0.095 11.8 0.4 0.15 11.1 0.4 1.2 1 0 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.14 OAP61504.1 - 0.32 9.8 1.1 1 8.1 0.4 2.0 1 1 0 2 2 2 0 Tryptophan halogenase MFS_1 PF07690.16 OAP61505.1 - 7.1e-14 51.5 84.2 6.4e-11 41.8 49.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily HET PF06985.11 OAP61506.1 - 2.6e-19 70.0 0.7 6.2e-19 68.8 0.2 1.9 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Fungal_trans_2 PF11951.8 OAP61507.1 - 7.6e-14 51.3 2.1 1.3e-13 50.5 0.4 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Methyltr_RsmB-F PF01189.17 OAP61507.1 - 0.045 13.4 0.0 0.09 12.4 0.0 1.4 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Ank_2 PF12796.7 OAP61509.1 - 4e-73 242.0 11.5 1.7e-11 44.5 0.0 11.1 7 3 3 11 11 11 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAP61509.1 - 6.9e-56 185.9 5.7 3e-07 30.9 0.0 15.6 9 4 6 16 16 16 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAP61509.1 - 2.6e-43 141.0 10.0 0.00082 19.6 0.0 19.3 21 0 0 21 21 21 9 Ankyrin repeat Ank PF00023.30 OAP61509.1 - 1.1e-31 107.9 21.4 0.0049 17.3 0.0 17.7 17 1 0 17 17 17 6 Ankyrin repeat Ank_5 PF13857.6 OAP61509.1 - 9.5e-30 102.3 6.9 0.00054 20.2 0.0 12.6 7 3 6 13 13 13 7 Ankyrin repeats (many copies) DUF3447 PF11929.8 OAP61509.1 - 1.5e-06 28.0 0.0 0.022 14.7 0.0 5.1 5 1 1 6 6 6 1 Domain of unknown function (DUF3447) Phage_T7_Capsid PF05396.11 OAP61509.1 - 0.00052 20.4 2.5 8 6.8 0.2 4.8 4 1 0 5 5 5 2 Phage T7 capsid assembly protein Shigella_OspC PF06128.11 OAP61509.1 - 0.091 12.5 0.2 51 3.5 0.0 4.0 5 0 0 5 5 5 0 Shigella flexneri OspC protein MPM1 PF17234.2 OAP61510.1 - 0.057 13.7 0.1 0.057 13.7 0.1 3.9 4 0 0 4 4 4 0 Mitochondrial peculiar membrane protein 1 DUF4449 PF14613.6 OAP61510.1 - 0.13 12.4 7.0 1.4 9.0 1.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4449) DUF883 PF05957.13 OAP61510.1 - 0.18 12.4 1.1 0.57 10.8 1.1 1.9 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Questin_oxidase PF14027.6 OAP61511.1 - 9.5e-104 347.6 2.3 1.1e-103 347.4 2.3 1.0 1 0 0 1 1 1 1 Questin oxidase-like adh_short_C2 PF13561.6 OAP61512.1 - 2.3e-47 161.5 0.0 4.9e-47 160.4 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP61512.1 - 1.3e-41 142.2 0.0 2.3e-41 141.4 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAP61512.1 - 6e-06 26.3 0.0 6.2e-05 23.0 0.0 2.0 2 0 0 2 2 2 1 KR domain 3HCDH_N PF02737.18 OAP61512.1 - 0.00076 19.4 0.0 0.0019 18.1 0.0 1.6 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 OAP61512.1 - 0.0082 16.3 0.0 0.015 15.5 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Epimerase PF01370.21 OAP61512.1 - 0.01 15.3 0.0 0.018 14.5 0.0 1.5 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 OAP61512.1 - 0.014 14.6 0.0 0.019 14.1 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein UDPG_MGDP_dh_N PF03721.14 OAP61512.1 - 0.051 13.1 0.0 0.11 12.1 0.0 1.6 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF1776 PF08643.10 OAP61512.1 - 0.089 12.1 0.0 0.25 10.7 0.0 1.6 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) GDP_Man_Dehyd PF16363.5 OAP61512.1 - 0.094 12.1 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Ribosomal_L31e PF01198.19 OAP61512.1 - 0.12 12.7 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L31e 2-Hacid_dh_C PF02826.19 OAP61512.1 - 0.12 11.7 0.0 0.64 9.3 0.0 1.9 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 OAP61512.1 - 0.18 12.1 0.0 0.3 11.4 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain ANAPC8 PF04049.13 OAP61515.1 - 3.4e-53 179.5 0.4 3.7e-52 176.1 0.1 2.4 2 0 0 2 2 2 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_1 PF00515.28 OAP61515.1 - 1.1e-20 72.5 3.7 0.00026 20.7 0.0 6.7 7 1 0 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.6 OAP61515.1 - 7.6e-17 60.1 14.8 1.5e-05 24.9 0.0 8.9 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_2 PF07719.17 OAP61515.1 - 1.3e-15 56.2 16.7 0.032 14.4 0.0 8.6 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_14 PF13428.6 OAP61515.1 - 5.2e-14 51.7 23.1 0.0029 18.3 0.1 8.5 8 1 1 9 9 8 5 Tetratricopeptide repeat TPR_11 PF13414.6 OAP61515.1 - 6.6e-11 41.7 1.6 8.1e-07 28.6 0.6 3.9 2 2 1 3 3 3 1 TPR repeat ANAPC3 PF12895.7 OAP61515.1 - 6.2e-08 32.8 15.3 0.083 13.1 0.3 6.5 6 0 0 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 OAP61515.1 - 8.4e-08 32.6 15.4 0.073 13.6 0.4 6.6 6 1 0 6 6 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 OAP61515.1 - 6.1e-07 29.6 15.4 0.42 10.9 0.3 6.7 6 1 1 7 7 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 OAP61515.1 - 9.7e-07 29.3 19.6 1.5e-05 25.5 0.0 6.2 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_6 PF13174.6 OAP61515.1 - 3.1e-06 27.5 17.1 5.3 7.9 0.0 8.8 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_17 PF13431.6 OAP61515.1 - 4e-06 26.8 9.0 1.7 9.2 0.0 7.0 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 OAP61515.1 - 0.0027 17.6 15.1 3.5 7.9 0.0 6.1 7 0 0 7 7 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 OAP61515.1 - 0.0033 17.5 14.6 0.0096 16.0 0.2 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat ChAPs PF09295.10 OAP61515.1 - 0.0091 15.0 0.1 11 4.9 0.0 3.2 2 1 1 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) PPR PF01535.20 OAP61515.1 - 0.38 11.1 3.8 40 4.8 0.2 3.8 4 0 0 4 4 4 0 PPR repeat TPR_10 PF13374.6 OAP61515.1 - 0.48 10.4 6.8 66 3.6 0.0 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat Pro_racemase PF05544.11 OAP61516.1 - 2.4e-61 207.6 0.0 3.3e-61 207.1 0.0 1.2 1 0 0 1 1 1 1 Proline racemase DUF1241 PF06840.11 OAP61517.1 - 0.065 12.9 0.1 0.1 12.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1241) Apc15p PF05841.11 OAP61518.1 - 1.2e-05 26.1 2.3 1.4e-05 25.9 0.0 2.3 3 0 0 3 3 3 1 Apc15p protein GATase_2 PF00310.21 OAP61519.1 - 2.1e-178 593.3 0.0 3.1e-178 592.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 OAP61519.1 - 4e-156 519.8 0.0 8.1e-156 518.8 0.0 1.5 2 0 0 2 2 2 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 OAP61519.1 - 9.8e-116 386.1 0.0 1.1e-113 379.4 0.0 2.3 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 OAP61519.1 - 4.6e-86 287.3 4.7 7.7e-86 286.5 4.7 1.4 1 0 0 1 1 1 1 GXGXG motif Pyr_redox_2 PF07992.14 OAP61519.1 - 4e-26 91.9 0.0 3.1e-25 89.0 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 OAP61519.1 - 6.3e-21 74.3 0.1 1.3e-20 73.2 0.1 1.6 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster DAO PF01266.24 OAP61519.1 - 2.9e-07 30.4 0.4 0.0045 16.6 0.2 2.6 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAP61519.1 - 9.5e-07 29.0 0.0 3.1e-06 27.3 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 OAP61519.1 - 1.7e-05 25.3 0.1 0.011 16.3 0.1 2.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 OAP61519.1 - 3.3e-05 23.4 0.0 6.1e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 OAP61519.1 - 7.9e-05 22.1 0.3 0.21 10.8 0.0 3.5 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAP61519.1 - 0.0003 19.6 0.2 0.00066 18.5 0.2 1.5 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.19 OAP61519.1 - 0.00071 18.9 0.5 0.0099 15.2 0.1 2.3 2 0 0 2 2 2 1 FAD binding domain FAD_binding_2 PF00890.24 OAP61519.1 - 0.00088 18.5 0.0 0.004 16.3 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 OAP61519.1 - 0.0014 18.0 0.1 0.0029 17.0 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 OAP61519.1 - 0.0024 17.2 0.0 0.16 11.2 0.0 2.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FMN_dh PF01070.18 OAP61519.1 - 0.012 14.7 2.1 0.054 12.5 1.7 2.1 2 0 0 2 2 2 0 FMN-dependent dehydrogenase Thi4 PF01946.17 OAP61519.1 - 0.017 14.4 0.6 0.054 12.7 0.1 2.0 2 0 0 2 2 2 0 Thi4 family NAD_binding_7 PF13241.6 OAP61519.1 - 0.047 14.1 3.5 8.5 6.9 0.0 3.2 4 0 0 4 4 2 0 Putative NAD(P)-binding Rossmann-like PF10727.9 OAP61519.1 - 0.12 12.3 1.0 2 8.3 0.0 2.5 2 0 0 2 2 2 0 Rossmann-like domain 2-Hacid_dh_C PF02826.19 OAP61519.1 - 0.15 11.4 0.0 0.43 9.9 0.0 1.7 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GIDA PF01134.22 OAP61519.1 - 0.16 11.0 1.1 0.39 9.8 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Nup54 PF13874.6 OAP61520.1 - 1.6e-35 122.2 4.2 1.6e-35 122.2 4.2 2.1 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.6 OAP61520.1 - 5.9e-12 46.3 67.0 1.1e-06 29.4 34.1 3.0 1 1 1 2 2 2 2 Nucleoporin FG repeat region Nup54_57_C PF18570.1 OAP61520.1 - 3.6e-07 29.6 2.1 3.6e-07 29.6 2.1 2.1 2 0 0 2 2 2 1 NUP57/Nup54 C-terminal domain Prominin PF05478.11 OAP61520.1 - 0.35 8.8 5.5 0.49 8.3 5.5 1.1 1 0 0 1 1 1 0 Prominin FapA PF03961.13 OAP61520.1 - 0.9 8.1 10.0 0.22 10.1 4.7 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A Spc7 PF08317.11 OAP61520.1 - 0.96 8.3 19.8 0.031 13.1 9.3 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein Sporozoite_P67 PF05642.11 OAP61520.1 - 1.9 6.5 8.2 2.5 6.1 8.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SKA2 PF16740.5 OAP61520.1 - 4.3 7.2 10.3 0.47 10.3 4.4 2.3 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 Peptidase_M3_N PF08439.10 OAP61520.1 - 4.5 7.6 6.1 15 5.9 0.1 3.3 2 1 1 3 3 3 0 Oligopeptidase F Tom5 PF10642.9 OAP61521.1 - 6.9e-13 48.4 0.1 1.1e-12 47.8 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial import receptor subunit or translocase MFS_1 PF07690.16 OAP61522.1 - 1.4e-28 99.9 32.2 2.1e-28 99.3 32.2 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily HTH_35 PF13693.6 OAP61522.1 - 0.14 12.2 0.2 1 9.5 0.0 2.5 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding PhaG_MnhG_YufB PF03334.14 OAP61522.1 - 9.1 6.6 11.5 0.36 11.1 0.6 3.8 4 1 0 4 4 4 0 Na+/H+ antiporter subunit PAN_4 PF14295.6 OAP61523.1 - 0.19 11.6 2.4 1 9.3 0.6 2.6 2 0 0 2 2 2 0 PAN domain Med26 PF08711.11 OAP61524.1 - 1.2e-13 50.8 0.0 2.5e-13 49.8 0.0 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain HIG_1_N PF04588.13 OAP61525.1 - 4e-05 23.8 0.9 4e-05 23.8 0.9 1.7 2 0 0 2 2 2 1 Hypoxia induced protein conserved region 4HBT_2 PF13279.6 OAP61526.1 - 3.7e-10 40.4 0.0 7.7e-10 39.3 0.0 1.6 2 0 0 2 2 2 1 Thioesterase-like superfamily Glyco_hydro_61 PF03443.14 OAP61527.1 - 6.2e-05 23.0 0.0 0.00011 22.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 His_Phos_2 PF00328.22 OAP61528.1 - 8.2e-35 120.9 0.0 1.3e-34 120.2 0.0 1.3 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Ank_2 PF12796.7 OAP61529.1 - 2.3e-101 332.5 16.1 1.4e-16 60.8 0.1 9.9 4 3 7 11 11 11 11 Ankyrin repeats (3 copies) Ank PF00023.30 OAP61529.1 - 3e-74 242.5 14.3 2.2e-06 27.8 0.0 15.9 16 0 0 16 16 16 12 Ankyrin repeat Ank_4 PF13637.6 OAP61529.1 - 3.3e-73 241.2 9.6 1.8e-10 41.1 0.0 13.8 6 3 9 15 15 15 13 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAP61529.1 - 5.5e-72 229.1 0.3 2e-05 24.6 0.0 16.9 17 0 0 17 17 17 13 Ankyrin repeat Ank_5 PF13857.6 OAP61529.1 - 9.9e-65 213.8 8.7 9.7e-09 35.3 0.0 13.7 5 4 10 15 15 15 12 Ankyrin repeats (many copies) CorA PF01544.18 OAP61529.1 - 1.1e-09 38.1 0.7 2.4e-09 36.9 0.7 1.6 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Blt1 PF12754.7 OAP61530.1 - 5.9e-41 140.3 0.1 5.9e-41 140.3 0.1 1.5 2 0 0 2 2 2 1 Blt1 N-terminal domain Blt1_C PF17183.4 OAP61530.1 - 2.8e-14 52.4 0.2 4.3e-14 51.8 0.2 1.3 1 0 0 1 1 1 1 Get5 carboxyl domain ubiquitin PF00240.23 OAP61530.1 - 0.075 12.8 0.2 0.19 11.5 0.0 1.8 2 0 0 2 2 2 0 Ubiquitin family DUF2072 PF09845.9 OAP61531.1 - 0.18 12.1 0.9 0.44 10.8 0.9 1.7 1 0 0 1 1 1 0 Zn-ribbon containing protein SAT PF16073.5 OAP61532.1 - 7.2e-73 245.3 1.0 7.2e-73 245.3 1.0 2.4 3 0 0 3 3 3 1 Starter unit:ACP transacylase in aflatoxin biosynthesis ketoacyl-synt PF00109.26 OAP61532.1 - 3.7e-72 242.9 0.0 6.6e-72 242.1 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 OAP61532.1 - 8.3e-37 127.4 0.0 1.6e-36 126.4 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 OAP61532.1 - 1.1e-35 122.2 0.0 3.8e-35 120.4 0.0 2.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.25 OAP61532.1 - 3e-22 78.7 6.7 3.9e-12 46.3 0.7 2.5 2 0 0 2 2 2 2 Phosphopantetheine attachment site Thioesterase PF00975.20 OAP61532.1 - 3.1e-19 70.0 0.0 1.5e-18 67.7 0.0 2.3 2 0 0 2 2 2 1 Thioesterase domain PS-DH PF14765.6 OAP61532.1 - 3.5e-12 46.2 0.0 1.4e-11 44.2 0.0 1.9 2 0 0 2 2 2 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 OAP61532.1 - 7.6e-08 32.8 0.0 1.9e-07 31.5 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Abhydrolase_6 PF12697.7 OAP61532.1 - 3e-05 24.7 0.3 0.012 16.2 0.0 2.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Thiolase_N PF00108.23 OAP61532.1 - 0.0079 15.6 0.0 0.022 14.1 0.0 1.7 1 0 0 1 1 1 1 Thiolase, N-terminal domain Fungal_trans_2 PF11951.8 OAP61533.1 - 5.6e-27 94.5 0.7 2e-25 89.5 0.7 2.2 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP61533.1 - 0.00053 20.1 3.8 0.00093 19.3 3.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_4 PF01565.23 OAP61534.1 - 7.6e-22 77.6 0.1 1.6e-21 76.5 0.1 1.6 1 0 0 1 1 1 1 FAD binding domain MFS_1 PF07690.16 OAP61535.1 - 1.2e-07 31.0 34.8 6.1e-05 22.1 31.5 2.3 2 1 0 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.16 OAP61535.1 - 2.3e-07 30.6 7.3 8.1e-07 28.9 7.3 1.9 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 LAB_N PF07578.11 OAP61535.1 - 0.17 12.0 4.5 0.22 11.6 2.4 2.3 2 0 0 2 2 2 0 Lipid A Biosynthesis N-terminal domain OppC_N PF12911.7 OAP61535.1 - 0.18 11.8 1.7 4 7.5 0.0 3.2 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C Amidase PF01425.21 OAP61536.1 - 3.1e-99 333.0 0.0 3.8e-99 332.7 0.0 1.1 1 0 0 1 1 1 1 Amidase PhyH PF05721.13 OAP61537.1 - 1.4e-20 74.5 0.0 2.2e-20 73.8 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) HypA PF01155.19 OAP61537.1 - 0.0069 16.4 0.2 0.011 15.7 0.2 1.3 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DpnI PF06044.12 OAP61537.1 - 0.04 13.6 0.1 0.23 11.1 0.2 2.0 2 0 0 2 2 2 0 Dam-replacing family RNHCP PF12647.7 OAP61537.1 - 0.15 12.1 0.7 0.26 11.3 0.7 1.4 1 0 0 1 1 1 0 RNHCP domain zinc_ribbon_9 PF14369.6 OAP61537.1 - 0.15 12.3 2.3 0.42 10.9 2.2 1.8 1 1 1 2 2 2 0 zinc-ribbon Zn-ribbon_8 PF09723.10 OAP61537.1 - 0.2 11.8 2.6 0.37 11.0 2.6 1.4 1 0 0 1 1 1 0 Zinc ribbon domain C1_4 PF07975.12 OAP61537.1 - 0.58 10.4 3.6 2.1 8.7 3.2 2.0 1 1 1 2 2 2 0 TFIIH C1-like domain zinc_ribbon_4 PF13717.6 OAP61537.1 - 2.9 7.9 5.7 7.9 6.5 0.1 2.6 3 0 0 3 3 3 0 zinc-ribbon domain Proteasome PF00227.26 OAP61538.1 - 4.5e-55 186.1 0.1 5.9e-55 185.7 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 OAP61538.1 - 8.1e-13 47.8 0.2 2.1e-12 46.5 0.1 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature zf-CHCC PF10276.9 OAP61539.1 - 4.4e-15 55.4 3.5 7.3e-15 54.7 3.5 1.4 1 0 0 1 1 1 1 Zinc-finger domain MFS_1 PF07690.16 OAP61540.1 - 9e-42 143.2 49.6 2e-41 142.1 49.6 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 OAP61540.1 - 4e-11 42.0 16.6 5.4e-11 41.6 16.6 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Cu-oxidase_2 PF07731.14 OAP61541.1 - 3.3e-41 140.2 1.7 4.5e-37 126.8 0.0 3.4 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 OAP61541.1 - 6.4e-36 123.0 15.3 7.4e-36 122.8 1.9 4.8 4 1 1 5 5 5 1 Multicopper oxidase Cu-oxidase PF00394.22 OAP61541.1 - 1.1e-25 90.6 1.5 5.7e-25 88.3 0.4 2.5 2 0 0 2 2 2 1 Multicopper oxidase DUF4267 PF14087.6 OAP61542.1 - 1.5e-18 66.9 3.5 2e-18 66.5 3.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) Fungal_trans PF04082.18 OAP61543.1 - 7.4e-14 51.4 0.1 1.3e-13 50.6 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP61543.1 - 1.9e-08 34.3 12.1 3.2e-08 33.6 12.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DLH PF01738.18 OAP61544.1 - 2.2e-17 63.4 0.0 4.4e-17 62.4 0.0 1.5 1 1 0 1 1 1 1 Dienelactone hydrolase family 2H-phosphodiest PF08975.10 OAP61545.1 - 9.4e-40 135.2 0.0 1.8e-39 134.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1868) 2_5_RNA_ligase2 PF13563.6 OAP61545.1 - 0.00088 19.2 0.5 0.002 18.0 0.5 1.7 1 1 1 2 2 2 1 2'-5' RNA ligase superfamily CutC PF03932.14 OAP61546.1 - 1e-63 214.5 0.0 1.2e-63 214.2 0.0 1.0 1 0 0 1 1 1 1 CutC family UPF0047 PF01894.17 OAP61547.1 - 9e-38 129.0 0.0 1e-37 128.8 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 MPP6 PF10175.9 OAP61548.1 - 0.00061 20.3 0.0 0.00061 20.3 0.0 4.3 2 1 1 3 3 3 1 M-phase phosphoprotein 6 Utp14 PF04615.13 OAP61548.1 - 0.065 11.8 27.8 1.1 7.7 23.4 2.1 2 0 0 2 2 2 0 Utp14 protein FoP_duplication PF13865.6 OAP61549.1 - 0.1 13.2 6.5 0.2 12.2 6.5 1.4 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Histone PF00125.24 OAP61550.1 - 5.8e-17 62.3 0.0 7.6e-17 61.9 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 OAP61550.1 - 8.9e-13 47.7 0.1 2.1e-12 46.6 0.1 1.6 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 OAP61550.1 - 3.3e-05 24.1 0.0 4.9e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone R3H PF01424.22 OAP61551.1 - 7.8e-13 48.2 0.6 1.5e-12 47.3 0.6 1.5 1 0 0 1 1 1 1 R3H domain RRM_1 PF00076.22 OAP61551.1 - 1.6e-06 27.8 0.0 3.4e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_2 PF04059.12 OAP61551.1 - 0.045 14.0 0.0 0.075 13.3 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif 2 Aldo_ket_red PF00248.21 OAP61552.1 - 6e-12 45.4 0.1 5.4e-11 42.2 0.0 2.3 1 1 1 2 2 2 1 Aldo/keto reductase family CO_deh_flav_C PF03450.17 OAP61552.1 - 0.14 12.3 0.0 0.25 11.5 0.0 1.3 1 0 0 1 1 1 0 CO dehydrogenase flavoprotein C-terminal domain HSF_DNA-bind PF00447.17 OAP61553.1 - 9.7e-29 99.9 0.1 9.7e-29 99.9 0.1 2.1 3 0 0 3 3 3 1 HSF-type DNA-binding Golgin_A5 PF09787.9 OAP61553.1 - 0.0058 16.1 1.6 0.011 15.2 1.6 1.4 1 0 0 1 1 1 1 Golgin subfamily A member 5 APG6_N PF17675.1 OAP61553.1 - 0.086 13.4 5.9 0.77 10.3 5.2 2.5 2 1 0 2 2 2 0 Apg6 coiled-coil region Ets PF00178.22 OAP61553.1 - 0.087 13.3 0.0 0.22 12.0 0.0 1.6 1 0 0 1 1 1 0 Ets-domain SlyX PF04102.12 OAP61553.1 - 0.43 11.2 4.2 48 4.7 3.9 3.0 2 0 0 2 2 2 0 SlyX Spc7 PF08317.11 OAP61553.1 - 0.45 9.3 5.2 0.16 10.8 1.4 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein Baculo_PEP_C PF04513.12 OAP61553.1 - 4 7.5 7.0 5.1 7.1 3.4 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3450 PF11932.8 OAP61553.1 - 4.2 6.6 9.2 1.6 8.0 4.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) FUSC PF04632.12 OAP61553.1 - 9.9 4.6 5.7 2.2 6.7 1.2 2.0 2 1 0 2 2 2 0 Fusaric acid resistance protein family MFS_1 PF07690.16 OAP61554.1 - 5.5e-15 55.1 50.8 7.6e-08 31.7 20.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily SecG PF03840.14 OAP61554.1 - 0.041 14.0 0.1 0.041 14.0 0.1 3.0 3 1 1 4 4 4 0 Preprotein translocase SecG subunit DUF4231 PF14015.6 OAP61555.1 - 4.8 7.7 6.0 4.8 7.7 0.4 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) HET PF06985.11 OAP61556.1 - 9.7e-22 77.9 0.9 4.9e-14 52.9 0.1 2.8 2 1 0 2 2 2 2 Heterokaryon incompatibility protein (HET) PKD_3 PF16820.5 OAP61557.1 - 0.14 11.9 0.1 0.3 10.9 0.1 1.5 1 0 0 1 1 1 0 PKD-like domain zf-C2H2_4 PF13894.6 OAP61557.1 - 0.33 11.9 1.8 23 6.2 0.1 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger Pyr_redox_2 PF07992.14 OAP61558.1 - 3.4e-16 59.3 0.0 2.2e-13 50.1 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAP61558.1 - 1e-13 51.2 0.8 7.6e-13 48.4 0.4 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 OAP61558.1 - 4.2e-10 38.7 0.0 7.7e-10 37.8 0.0 1.5 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 OAP61558.1 - 2.6e-08 33.4 0.0 6.6e-06 25.5 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 OAP61558.1 - 2.9e-05 24.5 0.2 2 9.0 0.0 3.9 4 0 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OAP61558.1 - 0.0001 21.5 0.1 0.017 14.2 0.0 2.6 3 0 0 3 3 3 1 Lycopene cyclase protein Thi4 PF01946.17 OAP61558.1 - 0.0016 17.7 0.1 0.017 14.4 0.0 2.6 4 0 0 4 4 4 1 Thi4 family FAD_binding_3 PF01494.19 OAP61558.1 - 0.0059 15.9 0.0 0.018 14.3 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 OAP61558.1 - 0.009 16.2 0.1 0.044 14.0 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.20 OAP61558.1 - 0.011 15.8 0.0 0.18 11.8 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DAO PF01266.24 OAP61558.1 - 0.019 14.6 1.4 1.1 8.7 0.1 2.7 2 1 0 2 2 2 0 FAD dependent oxidoreductase F420_oxidored PF03807.17 OAP61558.1 - 0.025 15.2 0.3 5.6 7.6 0.0 2.7 3 0 0 3 3 2 0 NADP oxidoreductase coenzyme F420-dependent HI0933_like PF03486.14 OAP61558.1 - 0.027 13.2 0.5 0.54 8.9 0.1 2.6 3 0 0 3 3 3 0 HI0933-like protein 3HCDH_N PF02737.18 OAP61558.1 - 0.05 13.5 0.1 5.4 6.9 0.0 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 OAP61558.1 - 0.07 12.8 0.0 0.43 10.2 0.0 2.1 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA FAD_binding_2 PF00890.24 OAP61558.1 - 0.13 11.3 1.9 0.27 10.3 0.4 2.2 2 1 0 2 2 2 0 FAD binding domain DUF2024 PF09630.10 OAP61558.1 - 0.19 11.6 0.9 15 5.6 0.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF2024) TrkA_N PF02254.18 OAP61558.1 - 0.38 11.0 1.6 21 5.4 0.1 2.9 4 0 0 4 4 3 0 TrkA-N domain DUF3446 PF11928.8 OAP61560.1 - 2.8 8.3 25.4 0.78 10.1 8.0 2.8 3 0 0 3 3 3 0 Early growth response N-terminal domain Glug PF07581.12 OAP61561.1 - 9.4 6.9 10.6 2.1 8.9 4.0 3.3 3 0 0 3 3 3 0 The GLUG motif FMN_dh PF01070.18 OAP61562.1 - 2.5e-109 365.5 0.0 3.5e-109 365.0 0.0 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 OAP61562.1 - 6.5e-18 64.6 0.0 1.3e-17 63.7 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 OAP61562.1 - 4.1e-05 22.9 0.0 6.5e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 OAP61562.1 - 0.00012 21.2 0.5 0.00053 19.1 0.1 2.0 2 1 1 3 3 3 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 OAP61562.1 - 0.0015 18.0 0.0 0.0024 17.3 0.0 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase ThiG PF05690.14 OAP61562.1 - 0.019 14.3 0.0 0.21 10.8 0.0 2.1 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG Pro_isomerase PF00160.21 OAP61568.1 - 1.4e-35 122.9 0.0 2.5e-35 122.1 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD FMO-like PF00743.19 OAP61569.1 - 6e-24 84.4 0.0 5.1e-22 78.0 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OAP61569.1 - 2.6e-10 40.4 0.0 7.9e-10 38.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 OAP61569.1 - 5.2e-08 32.5 0.0 5.1e-07 29.2 0.0 2.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAP61569.1 - 4.8e-07 29.3 0.0 2.7e-05 23.6 0.0 2.5 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAP61569.1 - 7.6e-06 25.3 0.0 0.00099 18.3 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Amino_oxidase PF01593.24 OAP61569.1 - 0.0053 16.1 0.0 11 5.2 0.0 3.6 2 2 2 4 4 4 1 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 OAP61569.1 - 0.0061 16.6 0.1 0.27 11.2 0.0 3.0 3 0 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.17 OAP61569.1 - 0.12 11.6 0.0 7.5 5.7 0.0 2.3 2 0 0 2 2 2 0 Thi4 family FAD-oxidase_C PF02913.19 OAP61570.1 - 9.3e-61 205.6 0.0 1.3e-60 205.2 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 OAP61570.1 - 4.3e-38 130.2 0.3 1.4e-37 128.5 0.2 1.8 2 0 0 2 2 2 1 FAD binding domain Aldolase_II PF00596.21 OAP61572.1 - 1.3e-30 106.7 0.8 1.7e-30 106.3 0.8 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Nif11 PF07862.11 OAP61572.1 - 0.1 12.9 0.0 0.24 11.7 0.0 1.6 1 0 0 1 1 1 0 Nif11 domain GatB_N PF02934.15 OAP61572.1 - 0.12 11.7 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 GatB/GatE catalytic domain ABM PF03992.16 OAP61573.1 - 0.049 13.7 0.1 7.2 6.8 0.0 2.3 2 0 0 2 2 2 0 Antibiotic biosynthesis monooxygenase EF-hand_14 PF17959.1 OAP61573.1 - 0.13 12.6 0.0 0.26 11.7 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain FAD_binding_3 PF01494.19 OAP61574.1 - 4e-18 65.8 4.7 4.8e-10 39.2 1.7 3.1 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 OAP61574.1 - 3.1e-05 24.1 0.0 7.5e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 OAP61574.1 - 9.8e-05 21.6 0.0 0.00019 20.7 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAP61574.1 - 0.00013 21.7 0.0 0.001 18.8 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 OAP61574.1 - 0.00063 20.3 0.7 0.041 14.4 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAP61574.1 - 0.00063 19.1 0.0 0.021 14.1 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAP61574.1 - 0.0059 15.9 0.2 0.014 14.6 0.2 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 OAP61574.1 - 0.0064 16.7 0.2 0.017 15.4 0.1 1.7 2 0 0 2 2 2 1 TrkA-N domain Lycopene_cycl PF05834.12 OAP61574.1 - 0.016 14.2 0.1 0.024 13.7 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein HI0933_like PF03486.14 OAP61574.1 - 0.025 13.3 0.1 0.37 9.4 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.17 OAP61574.1 - 0.082 12.1 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Beta_helix PF13229.6 OAP61575.1 - 3.3e-12 46.5 9.6 2.2e-09 37.4 6.0 2.3 1 1 1 2 2 2 2 Right handed beta helix region Methyltransf_23 PF13489.6 OAP61576.1 - 2.8e-20 72.8 0.0 4.4e-20 72.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAP61576.1 - 3.4e-10 40.5 0.0 1.6e-09 38.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAP61576.1 - 5.6e-08 33.3 0.0 1.3e-07 32.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAP61576.1 - 2e-07 30.9 0.0 0.0092 15.8 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 OAP61576.1 - 1.5e-05 25.6 0.0 3.7e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 OAP61576.1 - 0.0031 17.0 0.0 0.0062 16.0 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase CMAS PF02353.20 OAP61576.1 - 0.0036 16.6 0.0 0.0087 15.4 0.0 1.5 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 OAP61576.1 - 0.0056 16.2 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 OAP61576.1 - 0.031 13.7 0.0 0.054 12.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.9 OAP61576.1 - 0.05 13.3 0.0 0.076 12.7 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase DUF938 PF06080.12 OAP61576.1 - 0.075 12.8 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_2 PF00891.18 OAP61576.1 - 0.14 11.4 0.0 0.29 10.4 0.0 1.6 1 0 0 1 1 1 0 O-methyltransferase domain p450 PF00067.22 OAP61577.1 - 1e-55 189.4 0.0 1.2e-55 189.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 G-patch_2 PF12656.7 OAP61578.1 - 0.11 12.6 0.1 0.23 11.5 0.1 1.5 1 0 0 1 1 1 0 G-patch domain Peptidase_C1 PF00112.23 OAP61580.1 - 9.1e-05 22.6 0.0 0.006 16.7 0.0 2.5 2 0 0 2 2 2 2 Papain family cysteine protease Abhydrolase_6 PF12697.7 OAP61581.1 - 1e-13 52.4 5.8 1.3e-13 52.0 5.8 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAP61581.1 - 0.0052 16.1 0.0 0.049 12.9 0.0 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 YjbE PF11106.8 OAP61581.1 - 0.17 12.1 2.7 1.5 9.1 0.1 2.2 2 0 0 2 2 2 0 Exopolysaccharide production protein YjbE Hexokinase_2 PF03727.16 OAP61582.1 - 5.9e-73 245.2 0.0 8.4e-73 244.7 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 OAP61582.1 - 1.1e-69 234.3 0.0 1.8e-69 233.6 0.0 1.3 1 0 0 1 1 1 1 Hexokinase DUF5441 PF17513.2 OAP61582.1 - 0.031 14.0 0.4 0.05 13.4 0.4 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5441) Isochorismatase PF00857.20 OAP61582.1 - 0.11 12.7 0.0 1.5 9.0 0.0 2.2 2 0 0 2 2 2 0 Isochorismatase family TAFII28 PF04719.14 OAP61583.1 - 4.2e-21 74.8 1.0 1.9e-20 72.7 1.0 2.0 1 1 0 1 1 1 1 hTAFII28-like protein conserved region AT_hook PF02178.19 OAP61583.1 - 0.0043 16.8 1.9 0.019 14.8 1.9 2.2 1 0 0 1 1 1 1 AT hook motif Phage_Gp23 PF10669.9 OAP61583.1 - 0.37 11.1 10.1 0.5 10.7 4.0 2.2 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) PKK PF12474.8 OAP61583.1 - 0.44 10.7 18.3 0.9 9.7 3.6 2.3 2 0 0 2 2 2 0 Polo kinase kinase GET2 PF08690.10 OAP61583.1 - 4.1 7.0 11.9 0.16 11.6 4.4 2.1 2 0 0 2 2 2 0 GET complex subunit GET2 CENP-X PF09415.10 OAP61583.1 - 4.2 7.8 7.6 0.22 11.8 0.8 2.5 2 0 0 2 2 2 0 CENP-S associating Centromere protein X Tannase PF07519.11 OAP61584.1 - 4e-82 276.6 0.2 5e-82 276.3 0.2 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase MtrB PF05440.12 OAP61584.1 - 0.15 12.5 0.0 4.3 7.8 0.0 2.3 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase subunit B Ank_2 PF12796.7 OAP61585.1 - 3.9e-15 56.2 0.3 4.9e-05 23.8 0.0 3.6 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAP61585.1 - 4.7e-09 36.6 1.9 5.2e-07 30.1 0.0 3.9 3 1 1 4 4 4 1 Ankyrin repeats (many copies) Ank PF00023.30 OAP61585.1 - 8.2e-08 32.4 0.6 0.098 13.1 0.3 4.3 3 1 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 OAP61585.1 - 1.6e-07 31.1 0.2 0.042 14.4 0.0 5.2 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 OAP61585.1 - 3.9e-06 27.0 1.1 0.0077 16.5 0.1 4.5 2 2 3 5 5 5 1 Ankyrin repeats (many copies) Pyr_redox_2 PF07992.14 OAP61586.1 - 4.5e-15 55.7 0.0 6.4e-12 45.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 OAP61586.1 - 4.9e-14 51.6 0.5 3.8e-12 45.4 0.0 2.4 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OAP61586.1 - 1.3e-11 44.3 0.0 2.3e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAP61586.1 - 1.7e-09 37.3 0.0 7.6e-09 35.2 0.0 1.8 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 OAP61586.1 - 1.3e-08 34.9 0.0 6.2e-07 29.6 0.0 3.4 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAP61586.1 - 2.1e-05 24.3 0.0 0.0085 15.7 0.0 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OAP61586.1 - 0.0034 16.5 0.0 0.0062 15.7 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 OAP61586.1 - 0.013 14.8 0.1 0.028 13.8 0.1 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 OAP61586.1 - 0.016 13.9 1.1 0.3 9.7 0.1 2.7 3 0 0 3 3 3 0 HI0933-like protein NAD_binding_9 PF13454.6 OAP61586.1 - 0.019 14.9 3.4 15 5.5 0.9 4.1 3 1 0 3 3 3 0 FAD-NAD(P)-binding GIDA PF01134.22 OAP61586.1 - 0.023 13.8 1.0 0.61 9.1 0.1 2.7 3 0 0 3 3 3 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 OAP61586.1 - 0.2 10.6 1.8 0.33 10.0 0.2 2.1 2 1 0 2 2 2 0 Lycopene cyclase protein Beta-lactamase PF00144.24 OAP61587.1 - 3.6e-44 151.4 0.0 7.3e-44 150.3 0.0 1.4 1 1 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.20 OAP61587.1 - 0.16 11.4 0.0 0.24 10.8 0.0 1.2 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase Zn_clus PF00172.18 OAP61588.1 - 5.4e-06 26.4 12.4 2.9e-05 24.1 12.4 2.1 1 1 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Prot_inhib_II PF02428.15 OAP61588.1 - 4.1 7.9 5.1 17 5.9 0.5 2.4 2 0 0 2 2 2 0 Potato type II proteinase inhibitor family HET PF06985.11 OAP61589.1 - 3.3e-11 43.7 8.2 1.3e-09 38.6 1.9 2.7 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) SAM_decarbox PF01536.16 OAP61590.1 - 1.3e-131 438.8 0.0 1.6e-131 438.5 0.0 1.1 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase ParA PF10609.9 OAP61591.1 - 6.4e-82 274.7 0.1 2.1e-81 273.0 0.1 1.8 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 OAP61591.1 - 6.9e-10 39.1 0.0 3.2e-09 36.9 0.0 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.11 OAP61591.1 - 3.8e-08 33.0 0.0 2.9e-07 30.0 0.0 2.0 1 1 1 2 2 2 1 ATPase MipZ AAA_31 PF13614.6 OAP61591.1 - 1.2e-05 25.3 0.9 7.6e-05 22.7 0.9 2.1 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.15 OAP61591.1 - 3.3e-05 23.2 0.1 6.1e-05 22.3 0.1 1.4 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_25 PF13481.6 OAP61591.1 - 0.00015 21.4 0.0 0.00028 20.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 OAP61591.1 - 0.0011 18.0 0.1 0.0016 17.5 0.1 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_26 PF13500.6 OAP61591.1 - 0.0026 17.6 0.8 0.65 9.8 0.4 2.3 2 0 0 2 2 2 2 AAA domain CBP_BcsQ PF06564.12 OAP61591.1 - 0.0078 15.7 0.0 0.014 14.8 0.0 1.5 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ APS_kinase PF01583.20 OAP61591.1 - 0.019 14.9 0.0 0.029 14.2 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase Zeta_toxin PF06414.12 OAP61591.1 - 0.02 14.2 0.0 0.03 13.6 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin SRP54 PF00448.22 OAP61591.1 - 0.025 14.2 0.1 1 8.9 0.1 2.1 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Desulfoferrod_N PF06397.12 OAP61591.1 - 0.033 13.8 1.0 0.072 12.7 1.0 1.5 1 0 0 1 1 1 0 Desulfoferrodoxin, N-terminal domain AAA_16 PF13191.6 OAP61591.1 - 0.11 12.9 0.1 0.24 11.8 0.1 1.5 2 0 0 2 2 1 0 AAA ATPase domain CLP1_P PF16575.5 OAP61591.1 - 0.12 12.2 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop RsgA_GTPase PF03193.16 OAP61591.1 - 0.16 11.9 0.8 0.4 10.6 0.8 1.6 1 0 0 1 1 1 0 RsgA GTPase Amidohydro_1 PF01979.20 OAP61593.1 - 6.1e-53 180.3 0.0 7.4e-53 180.1 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 OAP61593.1 - 1.8e-10 40.9 0.7 4.9e-09 36.2 0.0 2.1 2 0 0 2 2 2 2 Amidohydrolase family A_deaminase PF00962.22 OAP61593.1 - 0.064 12.6 0.0 0.2 10.9 0.0 1.7 2 0 0 2 2 2 0 Adenosine/AMP deaminase SnoaL_4 PF13577.6 OAP61594.1 - 3.8e-28 98.2 0.6 5.5e-28 97.6 0.6 1.2 1 0 0 1 1 1 1 SnoaL-like domain RPE65 PF03055.15 OAP61595.1 - 5.2e-95 319.3 0.1 6.1e-95 319.1 0.1 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Aldedh PF00171.22 OAP61596.1 - 9.7e-158 525.5 1.0 1.1e-157 525.3 1.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 OAP61596.1 - 9.8e-05 21.9 0.1 0.27 10.6 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) LuxC PF05893.14 OAP61596.1 - 0.031 13.3 0.3 0.055 12.5 0.3 1.3 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) His_Phos_2 PF00328.22 OAP61598.1 - 4.6e-32 111.8 0.0 6.7e-32 111.3 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) 2-Hacid_dh_C PF02826.19 OAP61599.1 - 2e-38 131.5 0.0 2.6e-38 131.2 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 OAP61599.1 - 1.4e-18 66.9 0.0 1.7e-18 66.6 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain H_lectin PF09458.10 OAP61600.1 - 2.2e-45 152.7 0.3 2.4e-17 62.8 0.0 3.2 3 0 0 3 3 3 3 H-type lectin domain Peptidase_M1 PF01433.20 OAP61600.1 - 0.04 13.5 0.3 0.08 12.5 0.3 1.5 1 0 0 1 1 1 0 Peptidase family M1 domain Astacin PF01400.24 OAP61601.1 - 4.5e-06 26.4 0.1 1.3e-05 25.0 0.1 1.6 1 1 0 1 1 1 1 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.24 OAP61601.1 - 6.9e-06 26.0 1.7 0.0086 15.9 0.5 2.3 1 1 0 2 2 2 2 Matrixin Peptidase_M43 PF05572.13 OAP61601.1 - 0.0043 17.0 0.0 0.0067 16.3 0.0 1.3 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 OAP61601.1 - 0.0084 16.3 0.0 0.0093 16.1 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 OAP61601.1 - 0.013 16.0 0.0 0.02 15.4 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 OAP61601.1 - 0.018 14.7 0.0 0.023 14.3 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DUF4344 PF14247.6 OAP61601.1 - 0.031 13.9 0.0 0.22 11.2 0.0 1.9 2 0 0 2 2 2 0 Putative metallopeptidase Reprolysin_2 PF13574.6 OAP61601.1 - 0.071 13.0 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M57 PF12388.8 OAP61601.1 - 0.13 11.8 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Zincin_1 PF06262.11 OAP61601.1 - 0.16 12.1 0.1 0.31 11.2 0.1 1.4 1 0 0 1 1 1 0 Zincin-like metallopeptidase DUF4953 PF16313.5 OAP61601.1 - 0.2 10.9 0.2 0.38 9.9 0.2 1.4 1 0 0 1 1 1 0 Met-zincin Metallopep PF12044.8 OAP61601.1 - 0.23 10.0 0.6 0.39 9.3 0.6 1.3 1 0 0 1 1 1 0 Putative peptidase family FAD_binding_3 PF01494.19 OAP61604.1 - 6.5e-86 288.7 0.0 1.6e-85 287.5 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 OAP61604.1 - 4.5e-56 189.5 0.0 8.4e-56 188.6 0.0 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox_2 PF07992.14 OAP61604.1 - 0.00027 20.3 0.1 0.00057 19.2 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAP61604.1 - 0.00075 18.3 0.0 0.0015 17.4 0.0 1.4 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 OAP61604.1 - 0.0066 15.7 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 OAP61604.1 - 0.014 15.6 0.0 0.047 13.9 0.0 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 OAP61604.1 - 0.015 14.4 0.0 0.033 13.2 0.0 1.6 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_2 PF00890.24 OAP61604.1 - 0.017 14.2 0.0 0.029 13.5 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 OAP61604.1 - 0.03 14.9 0.0 0.081 13.5 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAP61604.1 - 0.038 13.2 0.0 0.059 12.6 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 OAP61604.1 - 0.1 11.9 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase DUF3425 PF11905.8 OAP61605.1 - 1.8e-12 47.3 0.1 3.4e-12 46.4 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Ribonuc_L-PSP PF01042.21 OAP61606.1 - 6e-18 65.0 0.0 7e-18 64.8 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Flavin_Reduct PF01613.18 OAP61607.1 - 1.5e-18 67.3 0.0 2.1e-18 66.8 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain Dabb PF07876.12 OAP61608.1 - 1.1e-09 38.8 0.0 1.3e-09 38.6 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain p450 PF00067.22 OAP61609.1 - 1.7e-67 228.2 0.0 2.2e-67 227.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4145 PF13643.6 OAP61609.1 - 0.02 15.0 0.0 0.059 13.5 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4145) Abhydrolase_3 PF07859.13 OAP61610.1 - 9.6e-22 77.9 0.2 2.1e-20 73.5 0.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OAP61610.1 - 7.5e-11 41.9 0.4 0.00016 21.2 0.1 2.6 3 0 0 3 3 3 2 Prolyl oligopeptidase family Chlorophyllase2 PF12740.7 OAP61610.1 - 1.1e-07 31.1 0.0 1.4e-07 30.7 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase enzyme Esterase PF00756.20 OAP61610.1 - 8e-07 29.0 0.0 1.5e-06 28.1 0.0 1.5 1 1 0 1 1 1 1 Putative esterase COesterase PF00135.28 OAP61610.1 - 1.6e-06 27.3 0.5 1.2e-05 24.4 0.0 2.3 2 1 1 3 3 3 1 Carboxylesterase family Chlorophyllase PF07224.11 OAP61610.1 - 4.3e-06 26.0 0.0 5.6e-06 25.6 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase AXE1 PF05448.12 OAP61610.1 - 5.4e-06 25.3 0.1 0.002 16.9 0.0 2.1 1 1 0 2 2 2 2 Acetyl xylan esterase (AXE1) Peptidase_S15 PF02129.18 OAP61610.1 - 7.1e-05 22.5 0.0 0.00024 20.8 0.0 1.9 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Esterase_phd PF10503.9 OAP61610.1 - 8e-05 22.2 0.0 0.36 10.3 0.0 2.3 2 0 0 2 2 2 2 Esterase PHB depolymerase DLH PF01738.18 OAP61610.1 - 0.0003 20.4 0.1 0.0088 15.6 0.1 2.3 2 1 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 OAP61610.1 - 0.0016 18.3 0.1 0.39 10.5 0.0 2.3 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase Say1_Mug180 PF10340.9 OAP61610.1 - 0.019 13.9 0.1 3.2 6.5 0.0 2.1 2 0 0 2 2 2 0 Steryl acetyl hydrolase Hydrolase_4 PF12146.8 OAP61610.1 - 0.019 14.2 0.0 0.36 10.0 0.0 2.1 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OAP61610.1 - 0.027 15.1 0.4 0.037 14.6 0.4 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2920 PF11144.8 OAP61610.1 - 0.041 13.1 0.0 0.11 11.6 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2920) BAAT_C PF08840.11 OAP61610.1 - 0.14 12.0 0.0 0.22 11.4 0.0 1.5 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal MFS_1 PF07690.16 OAP61611.1 - 4.4e-28 98.2 24.6 4.4e-28 98.2 24.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAP61611.1 - 4.1e-06 25.9 12.9 4.1e-06 25.9 12.9 2.5 3 0 0 3 3 3 1 Sugar (and other) transporter Dioxygenase_C PF00775.21 OAP61612.1 - 7.2e-39 133.1 0.0 1e-38 132.6 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 OAP61612.1 - 1.2e-31 108.4 0.0 2.1e-31 107.6 0.0 1.5 1 0 0 1 1 1 1 Catechol dioxygenase N terminus ADH_N_2 PF16884.5 OAP61613.1 - 3.5e-32 110.5 0.0 1.1e-31 108.9 0.0 1.9 1 1 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 OAP61613.1 - 2.9e-20 72.6 0.0 5.4e-20 71.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAP61613.1 - 9.6e-12 46.1 0.0 2e-11 45.1 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glyco_hydro_43 PF04616.14 OAP61614.1 - 1e-36 126.8 4.7 1.4e-36 126.3 4.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Herpes_capsid PF06112.11 OAP61614.1 - 5.6 7.0 10.3 10 6.1 10.3 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Fe-ADH PF00465.19 OAP61615.1 - 6.4e-63 212.8 0.0 7.2e-63 212.6 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 OAP61615.1 - 7.6e-10 38.9 0.0 9.9e-10 38.5 0.0 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Aldo_ket_red PF00248.21 OAP61617.1 - 1.4e-40 139.4 0.0 6.3e-39 133.9 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family T4BSS_DotH_IcmK PF12293.8 OAP61617.1 - 0.049 12.9 0.0 0.14 11.4 0.0 1.7 1 1 0 1 1 1 0 Putative outer membrane core complex of type IVb secretion Ras PF00071.22 OAP61618.1 - 1.4e-38 132.0 0.1 1.8e-38 131.7 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAP61618.1 - 9.5e-18 64.6 0.0 1.5e-17 63.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAP61618.1 - 6.8e-10 38.7 0.1 8.6e-10 38.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OAP61618.1 - 1.7e-07 31.0 0.0 2.1e-07 30.7 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OAP61618.1 - 0.00032 20.1 0.0 0.00038 19.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Choline_transpo PF04515.12 OAP61619.1 - 1.6e-25 90.0 18.7 1.6e-25 90.0 18.7 2.3 2 0 0 2 2 2 1 Plasma-membrane choline transporter PMT PF02366.18 OAP61620.1 - 5.4e-89 298.0 18.2 5.4e-89 298.0 18.2 1.7 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 OAP61620.1 - 2.1e-64 216.8 14.1 2.1e-64 216.8 14.1 2.6 2 1 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 OAP61620.1 - 9.3e-34 116.9 0.3 1.6e-33 116.2 0.3 1.2 1 0 0 1 1 1 1 MIR domain Fungal_trans PF04082.18 OAP61621.1 - 1e-08 34.6 0.5 1.9e-08 33.7 0.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP61621.1 - 7.4e-06 26.0 13.7 1.3e-05 25.2 13.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DAO PF01266.24 OAP61622.1 - 1.8e-20 73.9 12.6 8.4e-19 68.3 12.6 2.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase CAF1A PF12253.8 OAP61623.1 - 1.4e-18 66.8 6.3 1.4e-18 66.8 6.3 3.6 3 1 0 3 3 2 1 Chromatin assembly factor 1 subunit A RR_TM4-6 PF06459.12 OAP61623.1 - 0.011 15.6 18.3 0.011 15.6 18.3 1.8 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Zip PF02535.22 OAP61623.1 - 0.17 11.1 2.1 0.23 10.6 2.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter SprA-related PF12118.8 OAP61623.1 - 0.22 10.6 13.0 0.35 10.0 13.0 1.2 1 0 0 1 1 1 0 SprA-related family DDHD PF02862.17 OAP61623.1 - 0.36 11.0 3.5 0.64 10.1 3.5 1.4 1 0 0 1 1 1 0 DDHD domain RNA_pol_3_Rpc31 PF11705.8 OAP61623.1 - 0.59 10.3 25.2 1.5 9.0 1.3 2.8 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 DUF5427 PF10310.9 OAP61623.1 - 0.85 8.5 17.0 1.6 7.6 17.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5427) DUF2151 PF10221.9 OAP61623.1 - 1.9 7.0 10.3 2.6 6.5 10.3 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator Raftlin PF15250.6 OAP61623.1 - 2.4 6.8 9.4 3.7 6.2 9.4 1.2 1 0 0 1 1 1 0 Raftlin CDC27 PF09507.10 OAP61623.1 - 2.5 7.4 31.4 0.037 13.4 21.5 2.3 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 Hamartin PF04388.12 OAP61623.1 - 3.4 6.2 9.9 5.1 5.6 9.9 1.2 1 0 0 1 1 1 0 Hamartin protein DUF4407 PF14362.6 OAP61623.1 - 3.4 6.9 17.1 4.9 6.4 17.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ndc1_Nup PF09531.10 OAP61623.1 - 6.3 5.4 4.5 9.7 4.7 4.5 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup GREB1 PF15782.5 OAP61623.1 - 6.5 3.7 7.9 8.7 3.3 7.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Pmp3 PF01679.17 OAP61625.1 - 2e-20 72.7 8.7 2.5e-20 72.4 8.7 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator DUF3481 PF11980.8 OAP61625.1 - 1.3 8.8 3.1 1.6 8.5 3.1 1.2 1 0 0 1 1 1 0 C-terminal domain of neuropilin glycoprotein Ank_2 PF12796.7 OAP61626.1 - 1.3e-26 93.0 0.0 1.1e-11 45.1 0.0 4.0 1 1 4 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.30 OAP61626.1 - 2e-14 53.3 0.4 0.00022 21.5 0.0 4.9 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 OAP61626.1 - 1.8e-13 50.4 1.0 0.00022 21.4 0.0 4.9 5 0 0 5 5 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAP61626.1 - 1.2e-12 46.8 0.5 8.8e-05 22.6 0.0 5.5 5 1 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.6 OAP61626.1 - 2.1e-11 44.1 0.1 0.067 13.8 0.0 4.7 3 1 1 4 4 4 3 Ankyrin repeats (many copies) TPR_2 PF07719.17 OAP61626.1 - 1.4e-08 34.2 4.2 0.00018 21.4 0.8 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 OAP61626.1 - 2.1e-07 31.1 8.7 0.00037 20.7 1.7 4.3 3 2 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 OAP61626.1 - 1e-06 28.3 1.1 0.0035 17.1 0.2 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 OAP61626.1 - 2.6e-06 27.8 0.4 2e-05 25.0 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 OAP61626.1 - 3.5e-05 23.5 0.4 1.1 9.5 0.2 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 OAP61626.1 - 5.1e-05 23.2 1.1 1.4 9.3 0.2 4.4 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_MalT PF17874.1 OAP61626.1 - 0.00029 20.3 0.3 0.63 9.4 0.0 2.5 1 1 1 2 2 2 2 MalT-like TPR region TPR_16 PF13432.6 OAP61626.1 - 0.00086 19.9 0.6 0.038 14.7 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 OAP61626.1 - 0.0038 17.9 4.4 6.1 8.0 0.2 4.5 4 0 0 4 4 3 1 Tetratricopeptide repeat HemY_N PF07219.13 OAP61626.1 - 0.033 14.4 0.4 0.1 12.8 0.4 1.8 1 0 0 1 1 1 0 HemY protein N-terminus TPR_10 PF13374.6 OAP61626.1 - 0.044 13.7 3.8 2.6 8.0 0.5 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Helo_like_N PF17111.5 OAP61626.1 - 0.059 12.7 0.2 0.22 10.9 0.2 2.0 1 1 0 1 1 1 0 Fungal N-terminal domain of STAND proteins RBM39linker PF15519.6 OAP61626.1 - 0.11 13.6 0.1 3.6 8.7 0.0 2.8 2 0 0 2 2 2 0 linker between RRM2 and RRM3 domains in RBM39 protein ANAPC3 PF12895.7 OAP61626.1 - 0.12 12.6 0.1 0.48 10.7 0.1 2.1 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF410 PF04190.13 OAP61626.1 - 0.13 12.1 1.1 23 4.7 0.2 3.2 3 1 0 4 4 3 0 Protein of unknown function (DUF410) TPR_6 PF13174.6 OAP61626.1 - 1.7 9.4 3.8 19 6.2 0.0 3.5 4 0 0 4 4 2 0 Tetratricopeptide repeat Fungal_trans PF04082.18 OAP61627.1 - 2.2e-19 69.5 0.0 3.5e-19 68.9 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ribosomal_L27 PF01016.19 OAP61629.1 - 2.7e-28 97.8 2.1 3e-28 97.6 0.1 2.0 2 0 0 2 2 2 1 Ribosomal L27 protein TPR_1 PF00515.28 OAP61630.1 - 1.4e-07 31.1 0.0 0.14 12.1 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 OAP61630.1 - 5.3e-07 29.3 0.1 0.092 12.9 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat UBA PF00627.31 OAP61630.1 - 3.4e-05 23.7 0.0 7.9e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain TPR_12 PF13424.6 OAP61630.1 - 0.034 14.4 0.4 0.18 12.1 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat ParB_C PF18064.1 OAP61630.1 - 0.052 13.7 0.1 0.5 10.6 0.0 2.4 2 0 0 2 2 2 0 Centromere-binding protein ParB C-terminal DUF1688 PF07958.11 OAP61631.1 - 7.7e-187 621.2 0.0 8.8e-187 621.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) Gtr1_RagA PF04670.12 OAP61632.1 - 3.9e-93 311.1 0.4 4.7e-93 310.8 0.4 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 OAP61632.1 - 2.6e-10 40.5 0.0 5.4e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 OAP61632.1 - 5.9e-10 39.0 0.0 1.1e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 OAP61632.1 - 4.7e-08 33.1 0.0 8.7e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 OAP61632.1 - 1.3e-07 31.2 0.0 1.9e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1_Xtn PF16897.5 OAP61632.1 - 0.00022 21.2 0.3 0.0025 17.8 0.1 2.2 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain GTP_EFTU PF00009.27 OAP61632.1 - 0.0011 18.6 0.0 0.002 17.7 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 OAP61632.1 - 0.0082 16.7 0.6 0.018 15.5 0.2 1.9 2 1 0 2 2 2 1 ABC transporter G-alpha PF00503.20 OAP61632.1 - 0.0092 15.2 4.2 1.4 8.0 1.2 2.7 1 1 2 3 3 3 2 G-protein alpha subunit AAA_29 PF13555.6 OAP61632.1 - 0.015 15.1 0.6 0.052 13.3 0.3 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain AIG1 PF04548.16 OAP61632.1 - 0.017 14.4 1.2 0.06 12.7 0.3 2.3 2 1 0 2 2 2 0 AIG1 family DUF815 PF05673.13 OAP61632.1 - 0.019 14.1 0.1 0.045 12.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RsgA_GTPase PF03193.16 OAP61632.1 - 0.021 14.7 1.8 0.31 10.9 0.0 2.9 3 1 0 3 3 3 0 RsgA GTPase SRPRB PF09439.10 OAP61632.1 - 0.023 14.1 0.0 0.035 13.5 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 OAP61632.1 - 0.059 12.9 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Zn_clus PF00172.18 OAP61633.1 - 1.6e-05 24.9 10.5 2.6e-05 24.2 10.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DIOX_N PF14226.6 OAP61634.1 - 1e-19 71.4 0.0 2.2e-19 70.3 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OAP61634.1 - 4.3e-16 59.3 0.0 7.3e-16 58.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily POTRA PF07244.15 OAP61634.1 - 0.15 12.6 0.1 3.8 8.1 0.1 2.3 2 0 0 2 2 2 0 Surface antigen variable number repeat Cupin_2 PF07883.11 OAP61635.1 - 1.3e-09 37.6 0.0 2.2e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Cupin domain GNAT_like PF18407.1 OAP61636.1 - 0.053 13.9 4.3 0.053 13.9 4.3 2.7 2 1 1 3 3 3 0 GCN5-related N-acetyltransferase like domain CoA_transf_3 PF02515.17 OAP61638.1 - 1.4e-66 225.1 0.0 3.4e-66 223.8 0.0 1.5 1 1 0 1 1 1 1 CoA-transferase family III DUF5590 PF17881.1 OAP61641.1 - 0.026 14.6 0.1 0.049 13.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5590) Cass2 PF14526.6 OAP61641.1 - 0.14 12.3 0.0 0.18 12.0 0.0 1.1 1 0 0 1 1 1 0 Integron-associated effector binding protein IPP-2 PF04979.14 OAP61644.1 - 6.6e-20 72.2 16.6 6.6e-20 72.2 16.6 2.0 2 1 0 2 2 2 1 Protein phosphatase inhibitor 2 (IPP-2) Tudor_3 PF18115.1 OAP61645.1 - 3.7e-19 68.3 0.0 7.7e-19 67.3 0.0 1.6 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain Rad9_Rad53_bind PF08605.10 OAP61645.1 - 2.5e-16 60.1 0.0 3.8e-16 59.4 0.0 1.3 1 0 0 1 1 1 1 Fungal Rad9-like Rad53-binding BRCT PF00533.26 OAP61645.1 - 0.0013 19.1 0.0 0.0033 17.8 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 OAP61645.1 - 0.0013 19.1 0.0 0.0036 17.7 0.0 1.8 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 OAP61645.1 - 0.058 13.3 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 Regulator of Ty1 transposition protein 107 BRCT domain Syndecan PF01034.20 OAP61646.1 - 0.00036 20.4 0.0 0.00063 19.6 0.0 1.4 1 0 0 1 1 1 1 Syndecan domain Adeno_E3_CR2 PF02439.15 OAP61646.1 - 0.0024 17.6 0.4 0.0047 16.7 0.4 1.4 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Protocadherin PF08374.11 OAP61646.1 - 0.015 15.3 0.2 0.1 12.6 0.0 2.1 2 0 0 2 2 2 0 Protocadherin TrbL PF04610.14 OAP61646.1 - 0.028 14.2 0.1 0.04 13.7 0.1 1.1 1 0 0 1 1 1 0 TrbL/VirB6 plasmid conjugal transfer protein EphA2_TM PF14575.6 OAP61646.1 - 0.11 13.4 0.0 0.19 12.6 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4271 PF14093.6 OAP61647.1 - 0.54 10.1 3.9 0.6 10.0 1.7 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4271) TMV_coat PF00721.21 OAP61647.1 - 0.59 10.0 3.5 0.39 10.5 0.3 2.0 2 0 0 2 2 2 0 Virus coat protein (TMV like) Zn_clus PF00172.18 OAP61648.1 - 1.3e-09 38.1 13.0 2.6e-09 37.1 13.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAP61648.1 - 1.9e-08 33.6 0.3 5.4e-08 32.2 0.1 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain tRNA_int_endo PF01974.17 OAP61649.1 - 2.7e-19 69.0 0.0 5.8e-19 67.9 0.0 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.14 OAP61649.1 - 4.3e-07 29.5 0.0 0.00012 21.7 0.0 2.4 2 0 0 2 2 2 2 tRNA intron endonuclease, N-terminal domain Nop10p PF04135.12 OAP61650.1 - 1.1e-19 70.2 0.8 1.5e-19 69.7 0.8 1.3 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family NOB1_Zn_bind PF08772.11 OAP61651.1 - 1.2e-31 108.6 3.5 2e-31 108.0 3.5 1.3 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like PIN_6 PF17146.4 OAP61651.1 - 1.8e-26 92.4 0.1 6.3e-26 90.7 0.0 2.0 2 0 0 2 2 2 1 PIN domain of ribonuclease HypA PF01155.19 OAP61651.1 - 0.011 15.8 1.1 0.18 11.8 1.5 2.1 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-NADH-PPase PF09297.11 OAP61651.1 - 0.014 15.1 3.0 0.027 14.1 1.0 2.3 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain zinc-ribbons_6 PF07191.12 OAP61651.1 - 0.15 12.0 4.4 0.26 11.3 4.4 1.3 1 0 0 1 1 1 0 zinc-ribbons Zn-ribbon_8 PF09723.10 OAP61651.1 - 0.23 11.6 2.4 0.35 11.0 1.3 1.9 2 0 0 2 2 2 0 Zinc ribbon domain DUF1387 PF07139.11 OAP61651.1 - 0.32 10.7 3.4 0.49 10.1 3.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) MFS_1 PF07690.16 OAP61652.1 - 8.6e-22 77.5 36.1 8.6e-22 77.5 29.9 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily EI24 PF07264.11 OAP61652.1 - 0.0068 16.7 4.4 0.0068 16.7 4.4 3.1 2 1 0 2 2 2 1 Etoposide-induced protein 2.4 (EI24) m04gp34like PF12216.8 OAP61652.1 - 0.13 11.8 0.1 0.23 11.0 0.1 1.3 1 0 0 1 1 1 0 Immune evasion protein Glyco_hydro_16 PF00722.21 OAP61653.1 - 1.2e-06 28.1 0.7 1.9e-06 27.5 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 POT1 PF02765.17 OAP61654.1 - 3.4e-10 39.9 0.0 6.2e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 Sdh_cyt PF01127.22 OAP61655.1 - 1.2e-21 76.9 6.8 1.8e-21 76.4 6.8 1.2 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Longin PF13774.6 OAP61656.1 - 0.15 12.1 0.2 0.43 10.6 0.0 1.9 2 0 0 2 2 2 0 Regulated-SNARE-like domain Phosphoesterase PF04185.14 OAP61658.1 - 1.2e-56 192.5 5.0 2.3e-56 191.5 5.0 1.5 1 1 0 1 1 1 1 Phosphoesterase family VIT1 PF01988.19 OAP61659.1 - 3.9e-66 223.0 1.2 4.5e-66 222.8 1.2 1.0 1 0 0 1 1 1 1 VIT family SyrA PF11089.8 OAP61659.1 - 1.2 9.3 4.2 1.5 9.0 0.7 2.3 2 0 0 2 2 2 0 Exopolysaccharide production repressor MFS_1 PF07690.16 OAP61660.1 - 3.5e-29 101.8 34.6 3.5e-29 101.8 34.6 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 OAP61660.1 - 2.2 6.5 11.1 0.51 8.5 4.5 2.8 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family AMP-binding PF00501.28 OAP61661.1 - 4.8e-58 196.7 0.0 6.6e-58 196.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAP61661.1 - 8.1e-13 49.2 0.0 2.2e-12 47.7 0.0 1.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain TraK PF06586.11 OAP61661.1 - 0.12 12.0 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 TraK protein Sugar_tr PF00083.24 OAP61662.1 - 1.1e-96 324.4 18.1 1.3e-96 324.3 18.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP61662.1 - 2e-18 66.5 35.8 1.3e-12 47.3 13.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.18 OAP61663.1 - 5.8e-15 55.0 0.0 1.1e-14 54.1 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Acetyltransf_1 PF00583.25 OAP61664.1 - 8.6e-12 45.3 0.0 1.2e-11 44.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OAP61664.1 - 2e-10 40.7 0.0 2.8e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OAP61664.1 - 8.8e-07 29.3 0.0 1.3e-06 28.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAP61664.1 - 2.7e-06 27.3 0.0 7e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 OAP61664.1 - 0.00025 21.7 0.0 0.00034 21.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 OAP61664.1 - 0.0032 17.6 0.0 0.012 15.7 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 OAP61664.1 - 0.012 15.7 0.0 0.025 14.7 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DUF4436 PF14494.6 OAP61665.1 - 0.0017 17.7 2.0 0.0025 17.2 2.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4436) CBP_BcsF PF11120.8 OAP61665.1 - 0.82 9.8 5.5 1.4 9.1 5.5 1.3 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsF SPC22 PF04573.12 OAP61666.1 - 1.4e-38 132.0 0.0 2.6e-28 98.7 0.0 2.1 2 0 0 2 2 2 2 Signal peptidase subunit adh_short_C2 PF13561.6 OAP61667.1 - 1.1e-30 107.0 0.7 1.3e-30 106.7 0.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP61667.1 - 5.9e-21 74.8 0.3 7.4e-21 74.5 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAP61667.1 - 4.7e-07 29.9 0.4 7.7e-07 29.2 0.4 1.3 1 0 0 1 1 1 1 KR domain Oxidored_nitro PF00148.19 OAP61667.1 - 0.00065 18.5 0.1 0.0011 17.8 0.1 1.3 1 1 0 1 1 1 1 Nitrogenase component 1 type Oxidoreductase DUF5641 PF18701.1 OAP61667.1 - 0.008 16.3 0.0 0.015 15.4 0.0 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5641) ADH_zinc_N PF00107.26 OAP61667.1 - 0.0087 16.0 0.3 0.061 13.3 0.1 2.2 2 1 0 2 2 2 1 Zinc-binding dehydrogenase NAD_binding_7 PF13241.6 OAP61667.1 - 0.024 15.1 0.1 0.044 14.2 0.1 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding TFIIA PF03153.13 OAP61668.1 - 8.4 6.3 17.2 15 5.4 17.2 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pkinase PF00069.25 OAP61669.1 - 9.8e-71 238.2 0.0 1.3e-70 237.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP61669.1 - 2.4e-33 115.5 0.0 7.9e-33 113.8 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OAP61669.1 - 0.00067 19.1 0.2 0.0016 17.8 0.2 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OAP61669.1 - 0.0043 16.4 0.0 0.013 14.8 0.0 1.7 1 1 1 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 OAP61669.1 - 0.012 14.6 0.2 0.15 11.0 0.0 2.0 2 0 0 2 2 2 0 Haspin like kinase domain Pkinase_fungal PF17667.1 OAP61669.1 - 0.053 12.3 0.0 0.11 11.2 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 OAP61669.1 - 0.35 10.8 7.5 1.7 8.5 0.0 3.2 3 1 1 4 4 4 0 Phosphotransferase enzyme family AAA PF00004.29 OAP61671.1 - 7.1e-16 58.8 0.0 2.1e-15 57.3 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 OAP61671.1 - 5.9e-15 55.4 0.0 2.3e-14 53.5 0.0 2.1 2 0 0 2 2 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 OAP61671.1 - 3e-12 46.6 0.0 1.5e-11 44.3 0.0 2.0 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 OAP61671.1 - 1.4e-08 34.9 0.0 2.9e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_assoc_2 PF16193.5 OAP61671.1 - 1e-06 29.0 0.0 3.3e-06 27.3 0.0 1.9 1 0 0 1 1 1 1 AAA C-terminal domain DNA_pol3_delta PF06144.13 OAP61671.1 - 1.5e-06 28.1 0.0 2.8e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_30 PF13604.6 OAP61671.1 - 3e-06 27.1 0.0 6.2e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 OAP61671.1 - 5.1e-06 26.8 0.0 2e-05 24.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OAP61671.1 - 9.6e-06 26.1 0.0 0.00055 20.4 0.0 2.6 2 1 0 3 3 2 1 AAA ATPase domain AAA_11 PF13086.6 OAP61671.1 - 1.6e-05 24.8 0.1 6.8e-05 22.8 0.0 1.7 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 OAP61671.1 - 6.6e-05 22.9 0.2 0.00062 19.8 0.1 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 OAP61671.1 - 0.00017 21.4 0.0 0.00047 19.9 0.0 1.8 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 OAP61671.1 - 0.00034 19.9 0.0 0.0006 19.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) ResIII PF04851.15 OAP61671.1 - 0.00051 20.1 0.0 0.17 11.9 0.0 2.2 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_14 PF13173.6 OAP61671.1 - 0.00076 19.5 0.0 0.019 15.0 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_24 PF13479.6 OAP61671.1 - 0.00096 18.9 0.0 0.0017 18.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 OAP61671.1 - 0.0017 18.1 0.1 0.011 15.5 0.0 2.1 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_3 PF07726.11 OAP61671.1 - 0.0028 17.5 0.0 0.017 14.9 0.1 2.4 2 1 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 OAP61671.1 - 0.0071 16.7 0.1 0.017 15.5 0.1 1.5 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 OAP61671.1 - 0.011 15.2 0.0 0.021 14.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region PhoH PF02562.16 OAP61671.1 - 0.013 14.9 0.0 0.79 9.1 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein DUF2075 PF09848.9 OAP61671.1 - 0.018 14.3 0.0 0.027 13.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_28 PF13521.6 OAP61671.1 - 0.019 15.2 0.0 0.035 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 OAP61671.1 - 0.021 15.3 0.0 0.037 14.6 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Mg_chelatase PF01078.21 OAP61671.1 - 0.023 14.1 0.1 0.12 11.8 0.1 2.2 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI TniB PF05621.11 OAP61671.1 - 0.039 13.4 0.0 0.19 11.1 0.0 2.0 1 1 0 1 1 1 0 Bacterial TniB protein TAFII28 PF04719.14 OAP61671.1 - 0.055 13.6 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 hTAFII28-like protein conserved region RNA_helicase PF00910.22 OAP61671.1 - 0.11 12.9 0.0 0.24 11.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase P21-Arc PF04062.14 OAP61672.1 - 1.4e-74 249.9 0.0 1.6e-74 249.7 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit Gcd10p PF04189.13 OAP61673.1 - 6.4e-117 390.0 0.0 8.2e-117 389.6 0.0 1.1 1 0 0 1 1 1 1 Gcd10p family HAD_2 PF13419.6 OAP61674.1 - 1.2e-11 45.1 0.0 4e-11 43.3 0.0 1.8 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OAP61674.1 - 1.1e-05 25.4 0.0 1.9e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 OAP61674.1 - 1.2e-05 25.7 0.0 1.6e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF202 PF02656.15 OAP61675.1 - 0.14 12.6 2.0 0.21 12.0 2.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF202) Mito_carr PF00153.27 OAP61676.1 - 1e-51 172.8 1.7 3.1e-17 62.3 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein HET PF06985.11 OAP61677.1 - 4.9e-26 91.8 0.1 1.1e-25 90.7 0.1 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) GFO_IDH_MocA PF01408.22 OAP61678.1 - 1.6e-14 54.8 0.0 2.4e-14 54.2 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Fungal_trans PF04082.18 OAP61679.1 - 1.1e-23 83.7 0.1 2.8e-23 82.3 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Abhydrolase_1 PF00561.20 OAP61680.1 - 9.3e-19 68.1 0.0 4.7e-18 65.8 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAP61680.1 - 2.5e-08 33.5 0.0 1.9e-07 30.6 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 OAP61680.1 - 2.4e-05 24.2 0.1 0.21 11.4 0.1 3.1 2 1 0 3 3 3 2 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 OAP61680.1 - 2.6e-05 25.0 0.1 3.5e-05 24.5 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.14 OAP61680.1 - 6.5e-05 21.8 0.0 0.0022 16.7 0.0 2.0 2 0 0 2 2 2 1 Ndr family Abhydrolase_5 PF12695.7 OAP61680.1 - 0.0052 16.6 0.0 1.2 8.9 0.0 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 OAP61680.1 - 0.022 14.2 0.0 3.7 7.0 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family DLH PF01738.18 OAP61680.1 - 0.1 12.1 0.0 1.5 8.3 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family Esterase_phd PF10503.9 OAP61680.1 - 0.14 11.6 0.0 19 4.6 0.0 2.6 2 1 1 3 3 3 0 Esterase PHB depolymerase FAD_binding_3 PF01494.19 OAP61681.1 - 1.5e-21 77.1 0.1 2.7e-21 76.2 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 OAP61681.1 - 5.5e-08 32.9 1.5 1.4e-07 31.7 1.5 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAP61681.1 - 3.8e-07 29.6 0.9 1.2e-06 28.0 0.9 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAP61681.1 - 4.5e-07 29.8 10.1 0.0028 17.3 7.6 2.5 3 0 0 3 3 3 2 FAD dependent oxidoreductase HI0933_like PF03486.14 OAP61681.1 - 1.7e-06 27.0 0.7 4.3e-06 25.7 0.7 1.6 1 1 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 OAP61681.1 - 2.7e-06 27.8 1.5 2.8e-05 24.6 0.7 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 OAP61681.1 - 2.7e-05 23.7 0.5 3.9e-05 23.2 0.5 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 OAP61681.1 - 8.3e-05 22.0 5.9 0.032 13.5 2.3 2.6 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase Trp_halogenase PF04820.14 OAP61681.1 - 0.00036 19.5 4.7 0.0027 16.6 3.6 2.4 3 0 0 3 3 3 1 Tryptophan halogenase FAD_binding_2 PF00890.24 OAP61681.1 - 0.0006 19.0 7.0 0.0012 18.0 7.0 1.5 1 0 0 1 1 1 1 FAD binding domain Rossmann-like PF10727.9 OAP61681.1 - 0.0026 17.6 0.7 0.01 15.7 0.9 1.9 2 0 0 2 2 2 1 Rossmann-like domain Pyr_redox_3 PF13738.6 OAP61681.1 - 0.0035 16.6 6.9 0.29 10.3 6.2 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OAP61681.1 - 0.0063 15.6 2.9 0.012 14.7 2.9 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 OAP61681.1 - 0.018 14.4 4.4 0.019 14.2 2.5 1.9 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 OAP61681.1 - 0.091 12.0 0.9 0.15 11.3 0.9 1.3 1 0 0 1 1 1 0 Thi4 family SE PF08491.10 OAP61681.1 - 0.11 11.5 0.0 0.26 10.3 0.0 1.6 1 1 0 1 1 1 0 Squalene epoxidase 3HCDH_N PF02737.18 OAP61681.1 - 1.5 8.7 3.5 3 7.7 3.5 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MFS_1 PF07690.16 OAP61682.1 - 4e-31 108.2 23.7 4e-31 108.2 23.7 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Aldedh PF00171.22 OAP61683.1 - 1.6e-148 495.1 0.1 1.8e-148 494.9 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 OAP61683.1 - 0.073 12.5 0.0 0.29 10.5 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1487) Ribosomal_S20p PF01649.18 OAP61683.1 - 0.21 12.2 0.2 0.56 10.9 0.0 1.7 2 0 0 2 2 2 0 Ribosomal protein S20 MFS_1 PF07690.16 OAP61684.1 - 4.6e-18 65.3 71.3 3.3e-14 52.6 44.2 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 OAP61685.1 - 1e-20 74.0 70.8 7.2e-15 54.8 38.3 3.1 1 1 3 4 4 4 2 Major Facilitator Superfamily Aldo_ket_red PF00248.21 OAP61686.1 - 4.6e-63 213.1 0.0 5.3e-63 212.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DHHA1 PF02272.19 OAP61686.1 - 0.03 14.7 0.9 0.092 13.2 0.5 1.9 2 0 0 2 2 2 0 DHHA1 domain Claudin_3 PF06653.11 OAP61686.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Tight junction protein, Claudin-like Epimerase PF01370.21 OAP61687.1 - 0.00011 21.8 0.0 0.00018 21.0 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family ERCC3_RAD25_C PF16203.5 OAP61688.1 - 1.9e-117 390.9 0.7 3.1e-117 390.2 0.7 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 OAP61688.1 - 2.9e-33 114.7 0.0 6.9e-33 113.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAP61688.1 - 7.5e-16 58.6 0.0 1.5e-15 57.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 OAP61688.1 - 9.8e-12 45.2 0.1 2.3e-11 44.0 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 OAP61688.1 - 1e-05 24.4 0.0 1.5e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain AAA_34 PF13872.6 OAP61688.1 - 0.00012 21.1 0.0 0.0002 20.4 0.0 1.3 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 DEAD PF00270.29 OAP61688.1 - 0.032 14.0 0.0 0.056 13.2 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase DUF4748 PF15932.5 OAP61689.1 - 2.3e-20 72.1 0.7 4.3e-20 71.2 0.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4748) Sec16_N PF12935.7 OAP61689.1 - 0.013 15.7 2.2 0.016 15.4 2.2 1.1 1 0 0 1 1 1 0 Vesicle coat trafficking protein Sec16 N-terminus CTD_bind PF04818.13 OAP61690.1 - 9.3e-15 55.2 0.4 4.9e-13 49.7 0.2 2.9 2 1 1 3 3 3 1 RNA polymerase II-binding domain. SOBP PF15279.6 OAP61690.1 - 0.0014 19.4 24.3 0.0028 18.3 24.3 1.4 1 0 0 1 1 1 1 Sine oculis-binding protein MOR2-PAG1_mid PF14228.6 OAP61690.1 - 0.016 12.9 0.2 0.024 12.3 0.2 1.2 1 0 0 1 1 1 0 Cell morphogenesis central region DUF2457 PF10446.9 OAP61690.1 - 5.2 6.1 17.0 11 5.1 17.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Peptidase_C48 PF02902.19 OAP61691.1 - 2.5e-33 115.8 0.1 4.5e-33 114.9 0.1 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain IF4E PF01652.18 OAP61692.1 - 1.2e-53 181.2 0.0 2e-53 180.5 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Phage_B PF02304.15 OAP61692.1 - 0.16 12.3 0.0 0.36 11.2 0.0 1.5 1 0 0 1 1 1 0 Scaffold protein B BCDHK_Adom3 PF10436.9 OAP61693.1 - 5e-34 117.5 0.1 4.7e-33 114.3 0.0 2.0 2 0 0 2 2 2 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 OAP61693.1 - 3.1e-05 24.4 0.0 0.00011 22.7 0.0 1.8 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 OAP61693.1 - 0.003 17.4 0.0 0.005 16.7 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 OAP61693.1 - 0.0056 16.6 0.0 0.55 10.2 0.0 2.3 1 1 1 2 2 2 2 Histidine kinase-like ATPase domain USP7_ICP0_bdg PF12436.8 OAP61694.1 - 4.8e-86 288.0 0.2 3.4e-84 281.9 0.0 2.5 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.6 OAP61694.1 - 1.8e-70 236.8 4.6 1.8e-69 233.6 0.3 3.6 3 1 1 4 4 4 1 Ubiquitin-specific protease C-terminal UCH PF00443.29 OAP61694.1 - 1.3e-46 159.3 0.5 2.2e-46 158.5 0.5 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OAP61694.1 - 3e-21 76.4 0.0 1.2e-20 74.4 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.26 OAP61694.1 - 1.5e-06 28.3 0.0 3.8e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 MATH domain Rad60-SLD PF11976.8 OAP61694.1 - 0.0041 16.9 0.1 2.3 8.1 0.0 4.0 3 0 0 3 3 3 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 OAP61694.1 - 0.012 15.4 0.4 18 5.2 0.0 4.4 5 0 0 5 5 5 0 Ubiquitin family PspC PF04024.12 OAP61694.1 - 0.19 11.6 0.1 15 5.5 0.1 2.7 3 0 0 3 3 3 0 PspC domain NAD_binding_4 PF07993.12 OAP61695.1 - 9.2e-37 126.6 0.0 1.4e-36 126.0 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 OAP61695.1 - 8.4e-24 83.9 0.0 1.4e-23 83.2 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 OAP61695.1 - 8.1e-12 45.1 0.0 1.3e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 OAP61695.1 - 4.2e-07 30.2 0.2 1e-06 29.0 0.1 1.8 2 0 0 2 2 2 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.19 OAP61695.1 - 0.00076 18.6 0.0 0.0017 17.4 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 OAP61695.1 - 0.089 11.9 0.0 0.36 9.9 0.0 2.0 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein DHQ_synthase PF01761.20 OAP61696.1 - 1e-52 178.9 0.0 1.7e-52 178.2 0.0 1.2 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.6 OAP61696.1 - 1.3e-10 41.4 0.0 2.2e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Methyltransf_3 PF01596.17 OAP61697.1 - 2e-12 46.8 0.0 2.6e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 OAP61697.1 - 8.8e-11 42.8 0.0 1.8e-10 41.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CmcI PF04989.12 OAP61697.1 - 0.091 12.4 0.0 0.24 11.1 0.0 1.8 2 1 0 2 2 2 0 Cephalosporin hydroxylase Vps16_C PF04840.12 OAP61698.1 - 0.042 12.9 0.0 0.062 12.3 0.0 1.2 1 0 0 1 1 1 0 Vps16, C-terminal region Abhydrolase_3 PF07859.13 OAP61699.1 - 9.3e-28 97.5 0.1 1.4e-27 96.9 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold EMP24_GP25L PF01105.24 OAP61700.1 - 1.8e-46 158.4 0.7 2.1e-46 158.2 0.7 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD SdrD_B PF17210.3 OAP61700.1 - 0.11 12.7 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 SdrD B-like domain adh_short PF00106.25 OAP61701.1 - 7.4e-41 139.8 0.0 1e-40 139.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP61701.1 - 5e-30 104.8 0.0 7.1e-30 104.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP61701.1 - 5.2e-10 39.5 0.0 7.5e-10 39.0 0.0 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 OAP61701.1 - 0.00011 21.7 0.0 0.00016 21.2 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 OAP61701.1 - 0.0004 19.9 0.0 0.00093 18.7 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 OAP61701.1 - 0.053 12.6 0.0 0.073 12.2 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain DHHA2 PF02833.14 OAP61702.1 - 8.1e-25 87.7 0.0 1.4e-24 86.9 0.0 1.4 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.20 OAP61702.1 - 1.5e-07 31.6 0.0 3.4e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 DHH family TGT PF01702.18 OAP61703.1 - 2.4e-65 221.0 0.0 2.9e-65 220.7 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Thymidylate_kin PF02223.17 OAP61704.1 - 9.4e-44 149.3 0.0 1.1e-43 149.1 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase CPT PF07931.12 OAP61704.1 - 0.0016 18.3 0.0 0.0025 17.7 0.0 1.3 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_16 PF13191.6 OAP61704.1 - 0.025 14.9 0.0 0.036 14.5 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain KTI12 PF08433.10 OAP61704.1 - 0.034 13.6 0.0 0.063 12.7 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_35 PF14516.6 OAP61704.1 - 0.04 12.8 0.0 0.056 12.3 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_22 PF13401.6 OAP61704.1 - 0.096 13.0 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain PRK PF00485.18 OAP61704.1 - 0.12 12.1 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GIY-YIG PF01541.24 OAP61705.1 - 3e-12 46.6 0.0 6e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 GIY-YIG catalytic domain zf-HC5HC2H PF13771.6 OAP61705.1 - 0.0098 16.1 2.5 0.022 15.0 2.5 1.5 1 0 0 1 1 1 1 PHD-like zinc-binding domain FANCL_C PF11793.8 OAP61705.1 - 0.018 15.2 4.4 0.031 14.5 4.4 1.3 1 0 0 1 1 1 0 FANCL C-terminal domain zf-HC5HC2H_2 PF13832.6 OAP61705.1 - 0.067 13.4 1.5 0.13 12.4 1.5 1.4 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-RING_2 PF13639.6 OAP61705.1 - 0.075 13.4 7.1 0.13 12.6 7.1 1.4 1 0 0 1 1 1 0 Ring finger domain FYDLN_acid PF09538.10 OAP61705.1 - 0.36 11.5 5.0 1.1 10.0 5.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) C1_1 PF00130.22 OAP61705.1 - 0.53 10.2 3.1 0.31 10.9 0.9 1.8 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Astro_capsid_p PF12226.8 OAP61705.1 - 2.4 7.2 8.4 0.86 8.7 5.5 1.7 2 0 0 2 2 2 0 Turkey astrovirus capsid protein IBR PF01485.21 OAP61705.1 - 3.2 8.0 6.2 11 6.3 6.4 1.8 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain PLU-1 PF08429.11 OAP61706.1 - 2.3e-93 313.0 13.0 2.9e-90 302.9 10.3 2.3 2 0 0 2 2 2 2 PLU-1-like protein JmjC PF02373.22 OAP61706.1 - 9e-44 148.6 0.2 2e-43 147.4 0.2 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase ARID PF01388.21 OAP61706.1 - 1e-20 74.2 0.1 2.6e-20 72.9 0.1 1.8 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain JmjN PF02375.17 OAP61706.1 - 7.2e-17 61.0 1.1 2.5e-16 59.3 1.1 2.0 1 0 0 1 1 1 1 jmjN domain zf-C5HC2 PF02928.16 OAP61706.1 - 2e-13 50.5 7.5 2e-13 50.5 7.5 2.1 2 0 0 2 2 2 1 C5HC2 zinc finger PHD PF00628.29 OAP61706.1 - 6.2e-13 48.4 39.3 1.2e-08 34.7 10.9 3.5 3 0 0 3 3 3 2 PHD-finger Prok-RING_1 PF14446.6 OAP61706.1 - 0.0049 16.8 6.4 0.0049 16.8 6.4 2.7 2 1 0 2 2 2 1 Prokaryotic RING finger family 1 zf-PHD-like PF15446.6 OAP61706.1 - 0.21 11.2 11.8 0.21 11.2 2.7 2.6 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain zf-RanBP PF00641.18 OAP61706.1 - 0.92 8.9 9.1 1.9 7.8 0.4 2.6 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others PHD_2 PF13831.6 OAP61706.1 - 9.9 5.8 19.4 0.17 11.4 6.4 2.8 2 0 0 2 2 2 0 PHD-finger MTHFR PF02219.17 OAP61707.1 - 5.1e-92 308.2 0.0 1.4e-91 306.8 0.0 1.6 1 1 0 1 1 1 1 Methylenetetrahydrofolate reductase Abhydrolase_3 PF07859.13 OAP61708.1 - 1.8e-58 197.9 0.0 2.3e-58 197.5 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 OAP61708.1 - 1.2e-10 40.9 0.1 3.6e-10 39.3 0.1 1.7 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 OAP61708.1 - 2.2e-05 24.1 0.0 0.11 11.9 0.0 2.4 2 0 0 2 2 2 2 Prolyl oligopeptidase family DLH PF01738.18 OAP61708.1 - 0.063 12.8 0.0 0.13 11.8 0.0 1.5 2 0 0 2 2 2 0 Dienelactone hydrolase family Pyr_redox_2 PF07992.14 OAP61709.1 - 8.9e-15 54.7 0.0 3.9e-12 46.0 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 OAP61709.1 - 6.4e-13 48.0 0.2 2.9e-10 39.2 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OAP61709.1 - 1e-08 35.2 0.1 5.5e-08 32.9 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 OAP61709.1 - 7.9e-08 31.8 0.0 9.6e-07 28.2 0.0 2.2 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 OAP61709.1 - 4.4e-06 26.2 0.0 0.00023 20.5 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAP61709.1 - 9.2e-05 22.5 0.8 0.0031 17.5 0.1 3.0 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 OAP61709.1 - 0.00083 19.9 0.2 0.45 11.1 0.1 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 OAP61709.1 - 0.0026 17.1 0.0 0.04 13.3 0.0 2.2 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 OAP61709.1 - 0.01 16.3 0.0 1.6 9.2 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding SnoaL_4 PF13577.6 OAP61710.1 - 7.2e-21 74.6 0.4 9.5e-21 74.2 0.4 1.2 1 0 0 1 1 1 1 SnoaL-like domain Ring_hydroxyl_B PF00866.18 OAP61710.1 - 0.0097 16.0 0.0 0.015 15.4 0.0 1.2 1 0 0 1 1 1 1 Ring hydroxylating beta subunit Sugar_tr PF00083.24 OAP61711.1 - 1.2e-64 218.9 29.5 1.4e-64 218.6 29.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP61711.1 - 1.3e-21 76.9 31.0 1.3e-21 76.9 31.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Popeye PF04831.13 OAP61711.1 - 4.3 7.5 13.9 0.25 11.5 0.7 3.0 3 0 0 3 3 3 0 Popeye protein conserved region adh_short_C2 PF13561.6 OAP61712.1 - 6.5e-65 219.0 0.8 7.7e-65 218.7 0.8 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP61712.1 - 9.3e-50 168.8 1.5 1.2e-49 168.5 1.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAP61712.1 - 4.1e-10 39.9 1.6 6.2e-10 39.3 1.6 1.2 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 OAP61712.1 - 0.016 15.5 0.2 0.038 14.2 0.2 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 OAP61712.1 - 0.12 11.9 0.9 1 8.8 0.9 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family FMO-like PF00743.19 OAP61713.1 - 9.9e-15 53.9 1.0 9.2e-12 44.1 1.0 2.8 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OAP61713.1 - 7.5e-10 38.9 0.0 1.6e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAP61713.1 - 1e-08 34.8 0.0 2.2e-06 27.1 0.0 2.5 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAP61713.1 - 4.7e-08 32.7 1.2 0.00014 21.2 0.0 3.4 3 1 1 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAP61713.1 - 5e-06 25.9 0.8 0.39 9.8 0.0 3.8 3 1 1 4 4 4 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 OAP61713.1 - 1.2e-05 25.1 0.8 0.49 9.9 0.1 3.3 2 1 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 OAP61713.1 - 0.0033 17.4 0.0 0.048 13.7 0.0 2.5 3 0 0 3 3 3 1 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 OAP61713.1 - 0.038 13.3 0.4 0.074 12.3 0.0 1.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 OAP61713.1 - 0.059 12.4 0.1 7.6 5.5 0.2 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A Shikimate_DH PF01488.20 OAP61713.1 - 0.12 12.4 0.0 9.5 6.3 0.0 2.9 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase DALR_1 PF05746.15 OAP61714.1 - 0.015 15.4 0.0 0.019 15.2 0.0 1.1 1 0 0 1 1 1 0 DALR anticodon binding domain Fib_alpha PF08702.10 OAP61714.1 - 0.029 14.5 0.2 0.25 11.5 0.2 1.8 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family LigB PF02900.18 OAP61714.1 - 0.068 12.2 0.0 0.071 12.2 0.0 1.1 1 0 0 1 1 1 0 Catalytic LigB subunit of aromatic ring-opening dioxygenase TUDOR PF00567.24 OAP61714.1 - 0.083 12.9 0.5 6.2 6.9 0.0 2.1 1 1 1 2 2 2 0 Tudor domain Fungal_trans PF04082.18 OAP61715.1 - 1.1e-16 60.6 0.5 1.8e-16 60.0 0.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ycf66_N PF07444.11 OAP61715.1 - 0.073 13.2 0.1 0.16 12.1 0.1 1.5 1 0 0 1 1 1 0 Ycf66 protein N-terminus Abhydrolase_3 PF07859.13 OAP61716.1 - 6.6e-58 196.0 0.0 8.3e-58 195.7 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 OAP61716.1 - 8.2e-05 21.7 0.1 0.00047 19.1 0.1 1.9 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 OAP61716.1 - 0.003 17.1 0.0 0.038 13.5 0.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family ADH_zinc_N PF00107.26 OAP61717.1 - 4e-21 75.4 0.1 7.7e-21 74.4 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAP61717.1 - 6.8e-21 74.2 0.2 1.1e-20 73.5 0.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 OAP61717.1 - 8.3e-06 25.3 0.1 1.5e-05 24.4 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 OAP61717.1 - 4.7e-05 23.6 0.3 9e-05 22.7 0.3 1.5 1 0 0 1 1 1 1 TrkA-N domain 2-Hacid_dh_C PF02826.19 OAP61717.1 - 0.00011 21.6 0.0 0.00022 20.6 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CMAS PF02353.20 OAP61717.1 - 0.0066 15.8 0.0 0.0098 15.2 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 OAP61717.1 - 0.0079 16.9 0.1 0.017 15.8 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAP61717.1 - 0.017 15.7 0.2 0.046 14.4 0.2 1.8 1 1 0 1 1 1 0 Methyltransferase domain 3HCDH_N PF02737.18 OAP61717.1 - 0.018 14.9 0.4 0.028 14.3 0.4 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ThiF PF00899.21 OAP61717.1 - 0.048 13.0 0.0 0.084 12.2 0.0 1.3 1 0 0 1 1 1 0 ThiF family ADH_zinc_N_2 PF13602.6 OAP61717.1 - 0.054 14.5 0.0 0.11 13.5 0.0 1.5 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Methyltransf_31 PF13847.6 OAP61717.1 - 0.13 12.1 0.1 0.51 10.1 0.1 1.9 2 0 0 2 2 2 0 Methyltransferase domain SnoaL_4 PF13577.6 OAP61718.1 - 1.1e-13 51.5 0.4 1.5e-13 51.0 0.4 1.2 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_2 PF12680.7 OAP61718.1 - 0.073 13.7 0.1 0.2 12.3 0.1 1.7 1 1 0 1 1 1 0 SnoaL-like domain Fungal_trans PF04082.18 OAP61719.1 - 0.31 10.0 5.5 2.4 7.1 5.5 2.2 1 1 0 1 1 1 0 Fungal specific transcription factor domain Fungal_trans PF04082.18 OAP61721.1 - 2.4e-16 59.6 0.2 3.5e-16 59.0 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP61721.1 - 7.4e-05 22.8 20.2 8e-05 22.7 17.1 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain OrfB_Zn_ribbon PF07282.11 OAP61721.1 - 2.5 8.1 12.6 10 6.1 11.3 2.3 2 0 0 2 2 2 0 Putative transposase DNA-binding domain HpcH_HpaI PF03328.14 OAP61722.1 - 3.8e-29 101.4 0.0 4.5e-29 101.2 0.0 1.0 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PEPcase_2 PF14010.6 OAP61722.1 - 0.063 11.8 0.0 0.088 11.3 0.0 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase Cyclase PF04199.13 OAP61723.1 - 3.3e-15 56.5 0.0 4.2e-15 56.2 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase FluMu_N PF17891.1 OAP61723.1 - 0.024 14.4 0.0 0.043 13.6 0.0 1.4 1 0 0 1 1 1 0 Mu-like prophage FluMu N-terminal domain Sugar_tr PF00083.24 OAP61724.1 - 2e-76 257.7 19.1 2.4e-76 257.4 19.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP61724.1 - 6.2e-20 71.4 40.8 9.5e-16 57.6 23.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TauD PF02668.16 OAP61725.1 - 2.8e-50 171.6 0.5 3.3e-50 171.4 0.5 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family FMO-like PF00743.19 OAP61726.1 - 6.2e-18 64.5 0.1 6e-16 58.0 0.1 2.5 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OAP61726.1 - 3e-09 37.0 0.5 6e-09 36.0 0.0 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAP61726.1 - 2.8e-06 26.8 0.0 4.6e-05 22.8 0.0 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAP61726.1 - 0.00021 20.5 0.0 0.0069 15.6 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 OAP61726.1 - 0.0018 17.6 0.0 0.011 15.0 0.0 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAP61726.1 - 0.0083 15.7 0.0 2.7 7.5 0.0 3.1 2 1 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 OAP61726.1 - 0.15 12.6 0.0 3.3 8.3 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase adh_short_C2 PF13561.6 OAP61727.1 - 1.4e-63 214.6 6.8 1.6e-63 214.4 6.8 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP61727.1 - 4.1e-45 153.6 6.1 5.2e-45 153.3 6.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAP61727.1 - 7.3e-11 42.3 3.9 1.1e-10 41.8 3.9 1.1 1 0 0 1 1 1 1 KR domain Ldh_1_N PF00056.23 OAP61727.1 - 0.00096 19.3 0.3 0.00096 19.3 0.3 2.0 2 1 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain Epimerase PF01370.21 OAP61727.1 - 0.002 17.7 0.5 0.007 15.9 0.2 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 OAP61727.1 - 0.017 15.4 0.3 0.027 14.7 0.3 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain 3HCDH_N PF02737.18 OAP61727.1 - 0.018 14.9 0.5 0.039 13.9 0.5 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 OAP61727.1 - 0.03 13.5 0.0 0.053 12.6 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein UDPG_MGDP_dh_N PF03721.14 OAP61727.1 - 0.034 13.7 0.3 0.072 12.7 0.1 1.6 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain p450 PF00067.22 OAP61728.1 - 1.9e-63 214.9 0.0 2.3e-63 214.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FMN_dh PF01070.18 OAP61729.1 - 6.9e-102 341.0 0.0 1.3e-101 340.2 0.0 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase adh_short PF00106.25 OAP61729.1 - 2.6e-45 154.3 0.1 4.1e-45 153.7 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP61729.1 - 6.9e-35 120.7 0.1 1e-34 120.1 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Cyt-b5 PF00173.28 OAP61729.1 - 2.5e-22 78.8 0.0 5.4e-22 77.7 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NMO PF03060.15 OAP61729.1 - 1.3e-05 24.7 0.1 2.3e-05 23.9 0.1 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 OAP61729.1 - 2.3e-05 23.6 0.0 5.9e-05 22.2 0.0 1.7 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 OAP61729.1 - 0.0067 15.6 0.1 0.012 14.8 0.1 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase KR PF08659.10 OAP61729.1 - 0.018 15.0 1.4 0.069 13.1 1.4 1.9 1 1 0 1 1 1 0 KR domain Epimerase PF01370.21 OAP61729.1 - 0.099 12.1 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Fungal_trans PF04082.18 OAP61730.1 - 1.4e-16 60.3 0.5 2e-16 59.8 0.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP61730.1 - 0.0002 21.4 7.1 0.00039 20.5 7.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ndc1_Nup PF09531.10 OAP61730.1 - 2 7.0 6.6 0.077 11.7 0.6 1.6 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup Lactamase_B PF00753.27 OAP61731.1 - 1.8e-08 34.6 2.7 8e-08 32.5 2.7 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OAP61731.1 - 0.0018 17.8 0.2 0.014 14.9 0.1 2.3 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 OAP61731.1 - 0.16 11.8 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain adh_short_C2 PF13561.6 OAP61732.1 - 2.1e-44 151.8 0.0 2.8e-44 151.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP61732.1 - 6.9e-31 107.2 0.0 8.3e-31 107.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase DUF3638 PF12340.8 OAP61733.1 - 6.9e-74 248.0 0.0 1.2e-73 247.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 OAP61733.1 - 8.1e-13 47.5 0.5 1.8e-12 46.4 0.5 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) WW PF00397.26 OAP61734.1 - 0.0012 18.8 2.6 0.0012 18.8 2.6 2.2 2 0 0 2 2 2 1 WW domain CRISPR_Cse2 PF09485.10 OAP61734.1 - 0.034 14.7 0.9 0.048 14.2 0.9 1.2 1 0 0 1 1 1 0 CRISPR-associated protein Cse2 (CRISPR_cse2) HSP9_HSP12 PF04119.12 OAP61734.1 - 0.041 14.3 0.6 0.13 12.6 0.1 2.0 2 0 0 2 2 2 0 Heat shock protein 9/12 VSG_B PF13206.6 OAP61734.1 - 0.32 10.2 0.8 0.43 9.8 0.8 1.2 1 0 0 1 1 1 0 Trypanosomal VSG domain GGACT PF06094.12 OAP61736.1 - 9.2e-20 71.5 0.2 1.4e-19 70.9 0.2 1.3 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like Septin PF00735.18 OAP61737.1 - 2.8e-113 377.9 0.3 3.8e-113 377.4 0.3 1.2 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 OAP61737.1 - 1.9e-07 31.2 0.0 4e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OAP61737.1 - 5.8e-06 26.3 0.0 3.5e-05 23.8 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 OAP61737.1 - 7.1e-06 25.7 2.7 6e-05 22.7 0.1 2.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 OAP61737.1 - 0.0016 18.7 0.7 0.0051 17.1 0.0 2.1 2 1 0 2 2 2 1 AAA domain Roc PF08477.13 OAP61737.1 - 0.002 18.3 0.1 0.0044 17.2 0.1 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Pox_A32 PF04665.12 OAP61737.1 - 0.002 17.6 0.1 0.0035 16.8 0.1 1.3 1 0 0 1 1 1 1 Poxvirus A32 protein AIG1 PF04548.16 OAP61737.1 - 0.0071 15.7 0.0 0.013 14.8 0.0 1.4 1 0 0 1 1 1 1 AIG1 family IIGP PF05049.13 OAP61737.1 - 0.0082 15.2 0.0 0.014 14.5 0.0 1.4 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Ras PF00071.22 OAP61737.1 - 0.016 14.8 0.2 0.068 12.8 0.1 2.1 2 0 0 2 2 2 0 Ras family AAA_24 PF13479.6 OAP61737.1 - 0.017 14.9 0.0 0.028 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 OAP61737.1 - 0.024 14.6 0.0 0.044 13.7 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.6 OAP61737.1 - 0.03 14.7 1.0 0.094 13.1 0.1 2.4 2 1 0 2 2 2 0 AAA ATPase domain T2SSE PF00437.20 OAP61737.1 - 0.035 13.2 0.2 0.12 11.5 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_25 PF13481.6 OAP61737.1 - 0.046 13.3 0.2 0.52 9.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.14 OAP61737.1 - 0.05 12.8 0.0 0.053 12.8 0.0 1.4 1 1 0 1 1 1 0 KAP family P-loop domain ABC_tran PF00005.27 OAP61737.1 - 0.054 14.0 0.1 0.23 12.0 0.0 2.0 2 0 0 2 2 2 0 ABC transporter FOXP-CC PF16159.5 OAP61737.1 - 0.056 14.1 1.0 0.16 12.6 0.2 2.2 1 1 1 2 2 1 0 FOXP coiled-coil domain Sigma54_activat PF00158.26 OAP61737.1 - 0.066 12.9 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain RNA_helicase PF00910.22 OAP61737.1 - 0.1 13.0 0.0 0.27 11.6 0.0 1.8 1 0 0 1 1 1 0 RNA helicase PduV-EutP PF10662.9 OAP61737.1 - 0.11 12.3 0.4 4.2 7.1 0.4 2.6 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.23 OAP61737.1 - 0.39 10.8 5.4 2.9 7.9 0.1 2.9 2 1 1 3 3 3 0 Dynamin family WD40 PF00400.32 OAP61738.1 - 5.1e-39 131.5 26.1 2.7e-08 34.3 0.2 12.4 12 0 0 12 12 12 8 WD domain, G-beta repeat Utp12 PF04003.12 OAP61738.1 - 1.7e-21 76.5 0.0 2.8e-21 75.9 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 OAP61738.1 - 2.6e-15 56.5 0.0 1.2 9.5 0.0 8.7 4 2 4 9 9 9 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OAP61738.1 - 2.6e-07 29.7 8.1 0.15 10.7 0.1 4.7 3 2 2 5 5 5 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 OAP61738.1 - 5.2e-07 28.9 0.0 2.7 6.9 0.0 5.3 4 2 2 6 6 6 4 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_3 PF13570.6 OAP61738.1 - 0.5 10.9 5.8 34 5.1 0.2 4.7 6 0 0 6 6 6 0 PQQ-like domain MFS_1 PF07690.16 OAP61739.1 - 2e-26 92.7 40.5 2e-26 92.7 40.5 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily MMPL PF03176.15 OAP61739.1 - 5.7 5.8 8.3 2 7.3 0.4 2.5 2 0 0 2 2 2 0 MMPL family Methyltransf_32 PF13679.6 OAP61740.1 - 1.5e-23 83.5 1.1 1.5e-23 83.5 1.1 2.5 2 1 0 2 2 2 1 Methyltransferase domain NUDIX PF00293.28 OAP61741.1 - 7.4e-16 58.4 0.4 1.4e-15 57.5 0.4 1.3 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.11 OAP61741.1 - 2.3e-09 37.8 0.0 7.1e-09 36.3 0.0 1.8 2 0 0 2 2 2 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.11 OAP61741.1 - 1.7e-07 30.8 2.2 2.9e-07 30.0 2.2 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain CN_hydrolase PF00795.22 OAP61742.1 - 1.4e-38 132.8 0.0 1.9e-38 132.3 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 OAP61742.1 - 7.3e-24 84.2 0.0 3.5e-23 82.0 0.0 1.9 1 1 0 1 1 1 1 NAD synthase RelE PF06296.12 OAP61742.1 - 0.11 12.6 0.0 0.43 10.7 0.0 1.9 2 0 0 2 2 2 0 RelE toxin of RelE / RelB toxin-antitoxin system GTP_cyclohydroI PF01227.22 OAP61743.1 - 1e-73 246.6 0.1 2.2e-73 245.5 0.2 1.5 2 0 0 2 2 2 1 GTP cyclohydrolase I QueF PF14489.6 OAP61743.1 - 0.0026 17.9 0.0 0.0063 16.6 0.0 1.6 1 0 0 1 1 1 1 QueF-like protein Cu_amine_oxidN2 PF02727.16 OAP61743.1 - 0.066 13.4 0.1 0.23 11.7 0.0 1.9 2 0 0 2 2 2 0 Copper amine oxidase, N2 domain DUF3638 PF12340.8 OAP61743.1 - 0.076 12.3 0.3 0.16 11.3 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3638) Abhydrolase_6 PF12697.7 OAP61744.1 - 1.9e-17 64.6 0.0 2.2e-17 64.4 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_8 PF06259.12 OAP61744.1 - 0.14 11.7 0.0 0.34 10.5 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase Ubie_methyltran PF01209.18 OAP61745.1 - 3.5e-16 59.3 0.0 9.8e-16 57.8 0.0 1.6 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 OAP61745.1 - 3.5e-16 59.6 0.0 7.1e-16 58.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAP61745.1 - 2.8e-14 53.6 0.0 5.8e-14 52.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAP61745.1 - 3e-10 40.1 0.0 3.9e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAP61745.1 - 6.3e-08 33.3 0.0 1.2e-07 32.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAP61745.1 - 1.9e-07 31.1 0.0 3.1e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Transglut_core PF01841.19 OAP61746.1 - 4.3e-10 40.0 0.0 9.5e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily HET PF06985.11 OAP61747.1 - 0.07 13.5 0.1 0.17 12.3 0.1 1.6 1 0 0 1 1 1 0 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.16 OAP61748.1 - 1.7e-35 122.6 25.9 4.6e-35 121.2 25.9 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily 5TM-5TMR_LYT PF07694.12 OAP61748.1 - 0.0048 16.4 2.6 0.48 9.9 0.0 2.8 2 0 0 2 2 2 2 5TMR of 5TMR-LYT SDA1 PF05285.12 OAP61749.1 - 0.023 14.1 13.1 0.033 13.6 13.1 1.2 1 0 0 1 1 1 0 SDA1 Rrp44_CSD1 PF17216.3 OAP61749.1 - 1.6 8.4 4.4 2.7 7.7 4.4 1.5 1 0 0 1 1 1 0 Rrp44-like cold shock domain adh_short PF00106.25 OAP61750.1 - 2.3e-31 108.8 1.4 3e-31 108.4 1.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP61750.1 - 7e-22 78.1 0.5 1.1e-21 77.5 0.5 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.15 OAP61750.1 - 2.5e-09 36.7 0.1 3.4e-09 36.3 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 OAP61750.1 - 6.4e-09 36.0 0.1 1e-08 35.3 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAP61750.1 - 0.0001 21.8 0.7 0.0009 18.8 0.7 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAP61750.1 - 0.00038 20.0 1.2 0.00061 19.3 0.1 1.7 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 OAP61750.1 - 0.0024 16.9 0.2 0.0035 16.4 0.2 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_7 PF13241.6 OAP61750.1 - 0.0067 16.8 0.9 0.014 15.8 0.4 1.7 2 0 0 2 2 2 1 Putative NAD(P)-binding Methyltransf_25 PF13649.6 OAP61750.1 - 0.0069 17.1 0.1 0.017 15.8 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Tgi2PP PF18250.1 OAP61750.1 - 0.013 15.7 0.0 0.051 13.8 0.0 1.9 2 0 0 2 2 2 0 Effector immunity protein Tgi2PP Shikimate_DH PF01488.20 OAP61750.1 - 0.075 13.1 0.1 0.13 12.3 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 OAP61750.1 - 0.08 13.5 0.7 0.15 12.7 0.2 1.7 2 0 0 2 2 1 0 NADP oxidoreductase coenzyme F420-dependent Urocanase PF01175.18 OAP61750.1 - 0.11 12.2 1.9 0.2 11.3 1.3 1.7 1 1 1 2 2 2 0 Urocanase Rossmann-like domain adh_short PF00106.25 OAP61751.1 - 4.5e-36 124.2 0.2 6.2e-36 123.7 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP61751.1 - 2e-27 96.3 0.2 8.3e-27 94.3 0.2 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP61751.1 - 0.0078 16.1 0.1 0.26 11.2 0.1 2.3 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 OAP61751.1 - 0.027 14.0 0.0 0.063 12.7 0.0 1.6 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.6 OAP61752.1 - 3.1e-63 213.5 1.0 3.5e-63 213.3 1.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP61752.1 - 9.7e-50 168.7 2.0 1.2e-49 168.5 2.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAP61752.1 - 1.5e-11 44.6 0.8 1.9e-11 44.2 0.8 1.2 1 0 0 1 1 1 1 KR domain DUF4133 PF13571.6 OAP61752.1 - 0.084 13.2 1.7 0.16 12.3 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4133) GST_N_3 PF13417.6 OAP61753.1 - 3.2e-17 62.7 0.0 6.1e-17 61.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 OAP61753.1 - 1.3e-16 60.6 0.0 2.5e-16 59.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OAP61753.1 - 1.3e-15 57.4 0.0 2.1e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 OAP61753.1 - 7e-14 51.9 0.0 1.3e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 OAP61753.1 - 3.5e-13 49.6 0.0 6.7e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OAP61753.1 - 1.2e-07 31.7 0.0 2e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MFS_1 PF07690.16 OAP61754.1 - 4.6e-24 85.0 28.1 4.6e-24 85.0 28.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAP61754.1 - 1.1e-06 27.8 11.4 1.1e-06 27.8 11.4 2.2 2 1 0 2 2 2 1 Sugar (and other) transporter GCS PF03074.16 OAP61755.1 - 1.3e-123 413.0 0.0 1.7e-123 412.6 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase GCS2 PF04107.13 OAP61755.1 - 0.00074 19.0 0.0 0.0013 18.2 0.0 1.3 1 0 0 1 1 1 1 Glutamate-cysteine ligase family 2(GCS2) PhyH PF05721.13 OAP61757.1 - 1.1e-19 71.6 0.0 1.4e-19 71.2 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Fungal_trans_2 PF11951.8 OAP61758.1 - 5.5e-53 180.1 0.8 7.3e-53 179.8 0.8 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain WD40 PF00400.32 OAP61759.1 - 8.1e-23 80.3 15.5 2.6e-07 31.2 0.7 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAP61759.1 - 1.5e-12 47.6 0.0 0.0098 16.2 0.0 4.8 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain PQQ PF01011.21 OAP61759.1 - 1.8e-07 30.8 0.0 0.0085 16.0 0.0 3.4 3 0 0 3 3 3 2 PQQ enzyme repeat BBS2_Mid PF14783.6 OAP61759.1 - 0.0041 17.1 0.8 4 7.5 0.0 4.3 4 1 0 5 5 5 1 Ciliary BBSome complex subunit 2, middle region PQQ_2 PF13360.6 OAP61759.1 - 0.024 14.2 7.5 0.027 14.0 3.2 2.5 1 1 1 2 2 2 0 PQQ-like domain NUMOD4 PF07463.11 OAP61759.1 - 0.067 13.4 1.1 10 6.4 0.1 3.3 3 0 0 3 3 3 0 NUMOD4 motif PQQ_3 PF13570.6 OAP61759.1 - 0.3 11.6 8.3 2.4 8.8 0.0 4.9 6 0 0 6 6 6 0 PQQ-like domain ACT_7 PF13840.6 OAP61760.1 - 6.4e-27 93.1 0.0 5.3e-17 61.4 0.0 3.5 3 0 0 3 3 3 3 ACT domain XRN_M PF17846.1 OAP61761.1 - 1.9e-99 333.6 6.2 3.9e-99 332.6 6.2 1.4 1 1 0 1 1 1 1 Xrn1 helical domain XRN_N PF03159.18 OAP61761.1 - 1.2e-97 326.1 0.0 1.2e-97 326.1 0.0 1.5 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus XRN1_D1 PF18332.1 OAP61761.1 - 3.5e-75 252.0 2.9 1e-74 250.5 0.0 2.2 2 0 0 2 2 2 1 Exoribonuclease Xrn1 D1 domain XRN1_D2_D3 PF18334.1 OAP61761.1 - 3.1e-33 113.8 0.7 1e-32 112.1 0.0 2.3 3 0 0 3 3 3 1 Exoribonuclease Xrn1 D2/D3 domain SH3_12 PF18129.1 OAP61761.1 - 1.4e-23 82.7 0.1 3.1e-23 81.6 0.1 1.6 1 0 0 1 1 1 1 Xrn1 SH3-like domain Xrn1_D3 PF18194.1 OAP61761.1 - 7.1e-08 32.4 0.0 2e-07 31.0 0.0 1.8 1 0 0 1 1 1 1 Exoribonuclease 1 Domain-3 Phage_TAC_4 PF08748.11 OAP61761.1 - 0.038 14.3 1.0 0.11 12.8 1.0 1.7 1 0 0 1 1 1 0 Phage tail assembly chaperone R3H PF01424.22 OAP61761.1 - 0.091 12.8 0.0 0.25 11.3 0.0 1.7 1 0 0 1 1 1 0 R3H domain DUF2533 PF10752.9 OAP61761.1 - 0.12 12.9 0.1 0.3 11.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2533) CAF1C_H4-bd PF12265.8 OAP61762.1 - 1.4e-28 98.9 0.7 8.5e-28 96.4 0.5 2.4 3 0 0 3 3 3 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 OAP61762.1 - 1e-25 89.5 8.5 5.2e-06 27.1 0.1 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAP61762.1 - 0.002 18.4 2.5 3.6 8.0 0.1 4.2 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Fungal_trans_2 PF11951.8 OAP61763.1 - 5.4e-12 45.2 1.1 7.6e-12 44.7 0.5 1.4 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP61763.1 - 2.6e-05 24.2 8.7 4.2e-05 23.6 8.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_N PF08240.12 OAP61764.1 - 1.3e-09 37.9 0.0 2.5e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAP61764.1 - 8.2e-08 32.3 0.0 1.6e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAP61764.1 - 0.015 16.3 0.0 0.033 15.2 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase TAF6_C PF07571.13 OAP61765.1 - 1.1e-29 102.6 0.0 2.2e-29 101.6 0.0 1.6 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain TAF PF02969.17 OAP61765.1 - 2.9e-24 85.0 0.1 7.2e-24 83.8 0.1 1.7 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.24 OAP61765.1 - 0.0036 17.7 0.2 0.0079 16.6 0.2 1.6 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 OAP61765.1 - 0.0037 17.5 0.0 0.016 15.5 0.1 2.1 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 OAP61765.1 - 0.043 13.9 0.1 0.13 12.4 0.1 1.7 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Redoxin PF08534.10 OAP61766.1 - 0.12 12.1 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Redoxin FeoB_associated PF12669.7 OAP61766.1 - 0.21 12.0 1.0 0.33 11.4 0.3 1.7 1 1 0 1 1 1 0 FeoB-associated Cys-rich membrane protein DUF3292 PF11696.8 OAP61768.1 - 0.0058 15.1 7.0 0.46 8.8 1.4 2.8 3 0 0 3 3 3 2 Protein of unknown function (DUF3292) DUF3325 PF11804.8 OAP61768.1 - 0.11 12.6 0.2 0.11 12.6 0.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3325) Reticulon PF02453.17 OAP61768.1 - 0.16 11.9 5.8 0.088 12.8 0.7 2.2 2 0 0 2 2 2 0 Reticulon Fungal_trans_2 PF11951.8 OAP61769.1 - 1.1e-07 31.0 0.0 1.7e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain RmlD_sub_bind PF04321.17 OAP61770.1 - 5.9e-57 193.0 0.0 7.3e-57 192.6 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 OAP61770.1 - 1.5e-26 93.4 0.0 1.9e-26 93.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAP61770.1 - 1.3e-15 57.6 0.2 1.8e-14 53.9 0.2 2.0 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 OAP61770.1 - 2.3e-11 43.4 1.3 2.3e-09 36.8 0.3 2.9 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 OAP61770.1 - 5.8e-11 41.9 0.1 1.4e-09 37.4 0.1 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 OAP61770.1 - 1.1e-09 37.8 0.2 2.8e-06 26.7 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein KR PF08659.10 OAP61770.1 - 0.0012 18.8 0.3 0.61 10.0 0.0 2.4 2 0 0 2 2 2 2 KR domain SET PF00856.28 OAP61771.1 - 4.7e-11 43.4 0.0 2.5e-10 41.0 0.0 2.4 1 1 0 1 1 1 1 SET domain preSET_CXC PF18264.1 OAP61771.1 - 4.6e-08 33.4 14.7 4.6e-08 33.4 14.7 3.6 3 1 0 3 3 3 1 CXC domain Pil1 PF13805.6 OAP61772.1 - 1e-126 421.9 0.0 1.3e-126 421.5 0.0 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 DUF2385 PF09539.10 OAP61772.1 - 0.025 15.1 0.2 1.8 9.2 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2385) FAM92 PF06730.11 OAP61772.1 - 0.044 13.2 1.9 0.068 12.6 0.8 1.8 1 1 1 2 2 2 0 FAM92 protein HD_2 PF12917.7 OAP61772.1 - 0.084 12.6 0.1 5.9 6.6 0.0 2.3 2 0 0 2 2 2 0 HD containing hydrolase-like enzyme PPL5 PF18168.1 OAP61772.1 - 0.15 11.4 0.4 0.26 10.5 0.4 1.3 1 0 0 1 1 1 0 Prim-pol family 5 Atg14 PF10186.9 OAP61772.1 - 0.2 10.7 2.0 8.5 5.4 0.1 2.3 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 AAR2 PF05282.11 OAP61772.1 - 1.7 7.9 4.1 2.2 7.6 3.7 1.3 1 1 0 1 1 1 0 AAR2 protein SUR7 PF06687.12 OAP61773.1 - 7.1e-38 130.4 14.8 8.7e-38 130.1 14.8 1.1 1 0 0 1 1 1 1 SUR7/PalI family KASH PF10541.9 OAP61773.1 - 0.14 12.4 1.5 0.18 12.1 0.1 1.9 2 0 0 2 2 2 0 Nuclear envelope localisation domain LapA_dom PF06305.11 OAP61773.1 - 0.83 9.5 0.0 0.83 9.5 0.0 3.3 4 0 0 4 4 4 0 Lipopolysaccharide assembly protein A domain LigD_N PF13298.6 OAP61774.1 - 3.9e-35 120.3 0.1 7.6e-35 119.4 0.1 1.5 1 0 0 1 1 1 1 DNA polymerase Ligase (LigD) Pirin PF02678.16 OAP61775.1 - 1.1e-21 76.8 1.2 3.4e-21 75.2 1.2 1.7 1 1 0 1 1 1 1 Pirin Cupin_2 PF07883.11 OAP61775.1 - 2.3e-07 30.4 3.5 2.5e-05 23.9 1.1 3.1 2 1 0 2 2 2 2 Cupin domain Pirin_C_2 PF17954.1 OAP61775.1 - 0.0012 19.0 0.0 0.017 15.3 0.0 2.5 2 1 0 2 2 2 1 Quercetinase C-terminal cupin domain Cupin_1 PF00190.22 OAP61775.1 - 0.046 13.3 0.0 0.085 12.5 0.0 1.4 1 0 0 1 1 1 0 Cupin MelC1 PF06236.11 OAP61775.1 - 0.057 13.5 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 Tyrosinase co-factor MelC1 ABC_tran PF00005.27 OAP61776.1 - 1.6e-48 164.7 0.1 2.7e-29 102.4 0.1 2.9 3 0 0 3 3 2 2 ABC transporter ABC_membrane PF00664.23 OAP61776.1 - 3.6e-36 125.2 22.0 1.8e-25 90.1 10.6 3.7 4 0 0 4 4 4 2 ABC transporter transmembrane region SMC_N PF02463.19 OAP61776.1 - 4.5e-11 42.6 1.2 4.7e-05 22.9 0.2 4.6 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 OAP61776.1 - 0.00033 21.2 0.9 0.11 13.0 0.0 3.4 3 0 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.23 OAP61776.1 - 0.00051 20.1 0.1 0.1 12.6 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_29 PF13555.6 OAP61776.1 - 0.00082 19.1 0.2 0.88 9.4 0.0 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 OAP61776.1 - 0.00086 19.2 0.1 1.8 8.4 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 OAP61776.1 - 0.0029 17.9 0.3 3.3 8.0 0.0 3.3 2 1 0 2 2 2 1 AAA domain DUF87 PF01935.17 OAP61776.1 - 0.0072 16.4 3.2 1.1 9.3 0.1 2.7 2 0 0 2 2 2 2 Helicase HerA, central domain T2SSE PF00437.20 OAP61776.1 - 0.0089 15.1 0.0 0.72 8.9 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_10 PF12846.7 OAP61776.1 - 0.011 14.6 0.0 1.3 7.8 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain AAA_25 PF13481.6 OAP61776.1 - 0.036 13.7 0.0 2.5 7.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.6 OAP61776.1 - 0.041 13.7 0.7 13 5.5 0.0 4.0 4 0 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 OAP61776.1 - 0.081 12.6 0.2 9.2 5.9 0.0 2.9 2 1 0 2 2 2 0 AAA domain PhoH PF02562.16 OAP61776.1 - 0.087 12.3 0.1 10 5.5 0.0 3.0 3 0 0 3 3 3 0 PhoH-like protein AAA_16 PF13191.6 OAP61776.1 - 0.11 12.9 8.5 0.17 12.2 0.1 3.4 4 0 0 4 4 4 0 AAA ATPase domain DUF2075 PF09848.9 OAP61776.1 - 0.11 11.7 0.0 1.7 7.8 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) IstB_IS21 PF01695.17 OAP61776.1 - 0.13 12.0 0.2 4.5 7.0 0.0 2.8 3 0 0 3 3 2 0 IstB-like ATP binding protein SbcCD_C PF13558.6 OAP61776.1 - 0.14 12.4 0.0 14 6.0 0.0 3.5 3 0 0 3 3 3 0 Putative exonuclease SbcCD, C subunit NACHT PF05729.12 OAP61776.1 - 0.4 10.6 2.1 1.2 9.0 0.1 2.7 3 0 0 3 3 3 0 NACHT domain Peptidase_M28 PF04389.17 OAP61777.1 - 1.5e-31 109.6 0.0 2.3e-31 109.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 MutS_V PF00488.21 OAP61780.1 - 6.8e-66 221.9 0.2 1.6e-65 220.7 0.2 1.7 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 OAP61780.1 - 1.6e-41 142.7 0.0 3.2e-41 141.7 0.0 1.5 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 OAP61780.1 - 5.5e-33 113.6 0.1 1.5e-32 112.2 0.1 1.8 2 0 0 2 2 2 1 MutS domain I MutS_II PF05188.17 OAP61780.1 - 8.9e-15 55.2 0.0 2.2e-14 53.9 0.0 1.7 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 OAP61780.1 - 2e-06 28.0 0.0 4.7e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 MutS family domain IV AAA_23 PF13476.6 OAP61780.1 - 0.0071 16.9 0.0 0.0071 16.9 0.0 2.4 3 0 0 3 3 3 1 AAA domain AAA_27 PF13514.6 OAP61780.1 - 0.027 14.1 0.0 0.062 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 OAP61780.1 - 0.034 14.5 0.2 0.26 11.6 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.6 OAP61780.1 - 0.053 13.3 0.1 0.12 12.1 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 OAP61780.1 - 0.11 11.8 0.0 0.3 10.3 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin AAA_21 PF13304.6 OAP61780.1 - 0.11 12.3 0.1 0.24 11.2 0.1 1.6 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 OAP61780.1 - 0.46 10.1 1.4 2.2 7.9 0.0 2.4 2 1 0 2 2 2 0 AAA ATPase domain tRNA-synt_1b PF00579.25 OAP61781.1 - 5.1e-74 249.2 0.0 6.6e-74 248.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) TyrRSs_C PF16714.5 OAP61781.1 - 1.2e-43 147.7 0.0 2.1e-43 146.9 0.0 1.4 1 0 0 1 1 1 1 Tyrosyl-tRNA synthetase C-terminal domain S4 PF01479.25 OAP61781.1 - 0.1 12.4 0.3 0.32 10.7 0.0 2.0 2 0 0 2 2 2 0 S4 domain Zn_clus PF00172.18 OAP61783.1 - 1.1e-05 25.4 8.7 2.8e-05 24.1 8.7 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RRN9 PF10680.9 OAP61784.1 - 4.4e-14 52.5 2.1 1.8e-13 50.6 0.3 3.0 2 1 0 2 2 2 1 RNA polymerase I specific transcription initiation factor zf-C2H2_aberr PF17017.5 OAP61784.1 - 0.015 15.4 0.2 0.2 11.8 0.0 2.1 2 0 0 2 2 2 0 Aberrant zinc-finger Zn_clus PF00172.18 OAP61784.1 - 0.038 14.1 7.0 0.1 12.8 7.0 1.7 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain PALP PF00291.25 OAP61785.1 - 1.3e-73 248.0 0.1 1.7e-73 247.6 0.1 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 OAP61785.1 - 7.2e-44 147.5 0.0 5.2e-21 74.2 0.0 2.3 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase HIG_1_N PF04588.13 OAP61786.1 - 6.8e-24 83.9 0.3 9.4e-24 83.4 0.3 1.2 1 0 0 1 1 1 1 Hypoxia induced protein conserved region Ctr PF04145.15 OAP61786.1 - 0.13 12.9 0.1 0.22 12.1 0.1 1.4 1 0 0 1 1 1 0 Ctr copper transporter family FTCD_C PF04961.12 OAP61786.1 - 0.24 11.1 2.9 2.1 8.1 3.5 1.9 2 0 0 2 2 2 0 Formiminotransferase-cyclodeaminase VSG_B PF13206.6 OAP61786.1 - 0.32 10.2 8.2 0.38 10.0 8.2 1.1 1 0 0 1 1 1 0 Trypanosomal VSG domain Nup88 PF10168.9 OAP61786.1 - 1.2 6.8 6.7 1.5 6.5 6.7 1.0 1 0 0 1 1 1 0 Nuclear pore component MAS20 PF02064.15 OAP61786.1 - 1.4 9.0 10.5 5.4 7.1 10.2 2.0 1 1 0 1 1 1 0 MAS20 protein import receptor TMPIT PF07851.13 OAP61786.1 - 6 6.0 9.0 14 4.8 0.0 2.0 1 1 1 2 2 2 0 TMPIT-like protein HSP70 PF00012.20 OAP61786.1 - 6.9 4.7 8.9 8.9 4.4 8.9 1.1 1 0 0 1 1 1 0 Hsp70 protein Complex1_LYR PF05347.15 OAP61787.1 - 1.7e-13 50.4 0.5 1.1e-12 47.8 0.0 2.6 3 0 0 3 3 3 1 Complex 1 protein (LYR family) zf-RING_2 PF13639.6 OAP61787.1 - 0.00018 21.8 5.6 0.00035 20.8 5.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 OAP61787.1 - 0.00039 20.2 3.9 0.00077 19.3 3.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Complex1_LYR_2 PF13233.6 OAP61787.1 - 0.0015 19.2 0.1 0.013 16.3 0.0 2.4 2 0 0 2 2 2 1 Complex1_LYR-like zf-C3HC4_2 PF13923.6 OAP61787.1 - 0.0028 17.4 2.2 0.0052 16.6 2.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAP61787.1 - 0.017 15.1 6.8 0.033 14.2 6.8 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.6 OAP61787.1 - 0.63 10.1 7.2 3.4 7.7 7.4 2.1 1 1 1 2 2 2 0 zinc-RING finger domain LidA_Long_CC PF18641.1 OAP61787.1 - 0.95 9.5 4.8 1.8 8.6 1.3 2.3 1 1 1 2 2 2 0 LidA long coiled-coil domain zf-C3HC4_4 PF15227.6 OAP61787.1 - 3.5 7.9 9.3 6.4 7.0 9.3 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING RCC_reductase PF06405.11 OAP61788.1 - 0.037 13.2 1.6 0.039 13.1 0.1 1.8 2 0 0 2 2 2 0 Red chlorophyll catabolite reductase (RCC reductase) DUF1223 PF06764.11 OAP61788.1 - 0.068 13.2 0.7 0.15 12.1 0.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1223) Pyr_redox_2 PF07992.14 OAP61789.1 - 3.4e-15 56.1 0.0 4.7e-12 45.7 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 OAP61789.1 - 2.2e-13 49.5 0.2 4.6e-12 45.1 0.0 2.1 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OAP61789.1 - 3.2e-10 39.8 0.0 2.8e-08 33.4 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAP61789.1 - 9.6e-10 38.1 0.0 3e-08 33.2 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 OAP61789.1 - 9.7e-09 35.3 0.0 1.6e-07 31.5 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAP61789.1 - 0.00063 19.4 0.7 0.12 12.0 0.0 3.1 3 2 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OAP61789.1 - 0.00095 18.4 0.0 0.0022 17.1 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 OAP61789.1 - 0.0055 16.0 0.4 0.012 14.8 0.0 1.7 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.12 OAP61789.1 - 0.0065 15.6 0.0 0.06 12.4 0.0 2.4 2 1 0 2 2 2 1 Lycopene cyclase protein HI0933_like PF03486.14 OAP61789.1 - 0.086 11.5 0.2 5.4 5.6 0.0 3.0 3 0 0 3 3 3 0 HI0933-like protein Shikimate_DH PF01488.20 OAP61789.1 - 0.15 12.1 0.0 3.7 7.6 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.6 OAP61789.1 - 0.25 11.3 1.5 47 3.9 0.1 3.8 3 1 0 4 4 4 0 FAD-NAD(P)-binding GIDA PF01134.22 OAP61789.1 - 2.1 7.3 4.3 3.8 6.5 0.0 2.5 3 0 0 3 3 3 0 Glucose inhibited division protein A WD40 PF00400.32 OAP61791.1 - 1.1e-19 70.4 11.5 1.4e-05 25.7 0.1 5.5 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAP61791.1 - 4.7e-08 33.2 0.0 0.41 11.0 0.0 4.4 4 1 0 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OAP61791.1 - 0.062 13.2 0.0 5.6 6.8 0.0 2.5 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Tom37 PF10568.9 OAP61792.1 - 2.3e-38 131.3 0.1 4.1e-38 130.5 0.1 1.4 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_N_4 PF17172.4 OAP61792.1 - 5.7e-09 36.6 0.0 1e-08 35.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 OAP61792.1 - 2e-08 33.9 0.1 8.8e-08 31.8 0.0 2.2 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OAP61792.1 - 2.6e-05 24.1 0.1 0.00023 21.1 0.1 2.4 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OAP61792.1 - 0.019 15.1 0.0 0.043 14.0 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OAP61792.1 - 0.15 12.3 0.0 0.36 11.1 0.0 1.8 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Zip PF02535.22 OAP61793.1 - 3.6e-66 223.7 4.1 4.2e-66 223.4 4.1 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter bZIP_1 PF00170.21 OAP61794.1 - 0.00012 22.1 12.0 0.0018 18.3 3.4 2.3 1 1 1 2 2 2 2 bZIP transcription factor GAS PF13851.6 OAP61794.1 - 0.018 14.4 1.6 0.027 13.8 1.6 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding ZapB PF06005.12 OAP61794.1 - 0.056 13.9 4.1 0.1 13.0 4.1 1.4 1 0 0 1 1 1 0 Cell division protein ZapB zf-CpG_bind_C PF12269.8 OAP61794.1 - 0.072 12.9 1.2 0.1 12.4 1.2 1.1 1 0 0 1 1 1 0 CpG binding protein zinc finger C terminal domain Jnk-SapK_ap_N PF09744.9 OAP61794.1 - 0.077 13.2 3.9 0.12 12.6 3.9 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 APG6_N PF17675.1 OAP61794.1 - 0.15 12.6 4.7 0.23 12.0 4.7 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region Spc7 PF08317.11 OAP61794.1 - 0.17 10.8 6.5 0.24 10.3 6.5 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Cnn_1N PF07989.11 OAP61794.1 - 0.28 11.4 1.8 0.49 10.6 1.8 1.4 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 Macoilin PF09726.9 OAP61794.1 - 0.28 9.7 4.2 0.39 9.2 4.2 1.1 1 0 0 1 1 1 0 Macoilin family bZIP_2 PF07716.15 OAP61794.1 - 0.32 11.1 14.4 1.5 9.0 2.8 2.4 1 1 1 2 2 2 0 Basic region leucine zipper Csm1_N PF18504.1 OAP61794.1 - 0.48 10.8 5.6 0.76 10.2 2.8 2.1 1 1 1 2 2 2 0 Csm1 N-terminal domain DUF5320 PF17253.2 OAP61794.1 - 0.58 11.2 4.2 0.22 12.6 1.8 1.6 2 0 0 2 2 1 0 Family of unknown function (DUF5320) ADIP PF11559.8 OAP61794.1 - 0.61 10.2 7.2 0.92 9.6 7.2 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF2205 PF10224.9 OAP61794.1 - 1.1 9.2 3.9 0.8 9.7 2.0 1.7 2 0 0 2 2 2 0 Short coiled-coil protein SlyX PF04102.12 OAP61794.1 - 3.1 8.5 6.2 7.6 7.2 5.0 2.3 1 1 1 2 2 2 0 SlyX Methyltransf_31 PF13847.6 OAP61795.1 - 7.9e-25 87.4 0.0 1.1e-24 87.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAP61795.1 - 2e-19 70.1 0.0 4e-19 69.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAP61795.1 - 2.2e-19 69.9 0.0 4.1e-19 69.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAP61795.1 - 1.6e-11 44.3 0.0 2.4e-11 43.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAP61795.1 - 4.7e-11 43.3 0.0 7.1e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAP61795.1 - 1.7e-08 34.1 0.0 2.3e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.13 OAP61795.1 - 3.5e-05 23.4 0.0 5.2e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) UPF0020 PF01170.18 OAP61795.1 - 4.3e-05 23.3 0.0 7.5e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_8 PF05148.15 OAP61795.1 - 0.0032 17.3 0.0 0.005 16.7 0.0 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase MTS PF05175.14 OAP61795.1 - 0.0075 15.8 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 OAP61795.1 - 0.017 14.5 0.0 0.024 13.9 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.18 OAP61795.1 - 0.076 12.3 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain PCMT PF01135.19 OAP61795.1 - 0.093 12.5 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) GTP_CH_N PF12471.8 OAP61796.1 - 4.5e-90 300.6 0.0 6.8e-90 300.0 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.20 OAP61796.1 - 2e-18 66.5 0.0 3.2e-18 65.9 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase II GntR PF00392.21 OAP61796.1 - 0.049 13.3 0.0 2 8.1 0.0 2.8 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family DUF1688 PF07958.11 OAP61797.1 - 2.3e-148 494.4 0.0 2.5e-148 494.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) Q_salvage PF10343.9 OAP61797.1 - 0.068 12.7 0.0 6.8 6.2 0.0 2.4 2 0 0 2 2 2 0 Potential Queuosine, Q, salvage protein family UPRTase PF14681.6 OAP61798.1 - 2e-55 187.5 0.1 7.4e-51 172.5 0.0 2.0 1 1 1 2 2 2 2 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 OAP61798.1 - 2.1e-06 27.4 0.0 3.3e-06 26.7 0.0 1.3 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Aldedh PF00171.22 OAP61799.1 - 1.2e-128 429.6 0.7 1.5e-128 429.3 0.7 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 OAP61799.1 - 1.1e-05 24.7 0.0 2e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) Cellulase PF00150.18 OAP61799.1 - 0.14 11.6 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) Pribosyltran_N PF13793.6 OAP61800.1 - 1.6e-41 140.9 0.0 1.3e-40 138.0 0.0 2.1 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 OAP61800.1 - 3.1e-31 108.8 2.4 1.6e-28 100.0 0.6 2.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 OAP61800.1 - 9.6e-09 34.9 1.1 1.9e-08 34.0 1.1 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 OAP61800.1 - 0.012 15.1 0.3 0.022 14.2 0.3 1.4 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Mito_morph_reg PF14972.6 OAP61800.1 - 0.12 12.0 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial morphogenesis regulator UPRTase PF14681.6 OAP61801.1 - 2.5e-63 213.3 0.0 2.9e-63 213.1 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 OAP61801.1 - 0.00018 21.1 0.0 0.00023 20.7 0.0 1.4 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Transp_cyt_pur PF02133.15 OAP61802.1 - 1.6e-127 426.0 37.4 1.9e-127 425.7 37.4 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin MOSC PF03473.17 OAP61803.1 - 1.1e-24 86.9 0.0 2.6e-24 85.7 0.0 1.7 1 0 0 1 1 1 1 MOSC domain Fer2 PF00111.27 OAP61803.1 - 8.5e-14 51.3 0.4 1.7e-13 50.3 0.4 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain 3-alpha PF03475.14 OAP61803.1 - 8.7e-09 35.1 0.0 1.8e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 3-alpha domain NAD_binding_1 PF00175.21 OAP61803.1 - 0.00013 22.6 0.1 0.0066 17.1 0.0 2.9 2 1 0 2 2 2 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 OAP61803.1 - 0.0013 18.9 0.0 1.9 8.6 0.0 2.4 2 0 0 2 2 2 2 Ferric reductase NAD binding domain Fer2_4 PF13510.6 OAP61803.1 - 0.015 15.3 0.2 0.073 13.1 0.1 2.1 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain DIOX_N PF14226.6 OAP61804.1 - 6e-36 123.8 0.0 9e-36 123.2 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OAP61804.1 - 8e-23 80.8 0.0 1.4e-22 80.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ADH_zinc_N PF00107.26 OAP61806.1 - 3.3e-11 43.3 0.0 8.6e-11 41.9 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAP61806.1 - 3.5e-05 24.9 0.0 6.4e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 OAP61806.1 - 0.00087 18.8 0.9 0.0059 16.1 0.9 2.0 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 OAP61806.1 - 0.031 13.6 0.1 0.045 13.0 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Tautomerase_3 PF14832.6 OAP61808.1 - 3.9e-09 36.8 0.0 4.7e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 Putative oxalocrotonate tautomerase enzyme YTH PF04146.15 OAP61809.1 - 1.5e-59 200.7 0.0 3e-59 199.7 0.0 1.5 1 0 0 1 1 1 1 YT521-B-like domain RRM_1 PF00076.22 OAP61809.1 - 3.8e-06 26.6 0.0 6.6e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OAP61809.1 - 0.0049 16.7 0.0 0.0092 15.8 0.0 1.3 1 0 0 1 1 1 1 Occluded RNA-recognition motif ArfGap PF01412.18 OAP61810.1 - 1.4e-32 112.3 1.1 2.8e-32 111.2 0.0 2.2 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf BAR_3 PF16746.5 OAP61810.1 - 8.8e-20 71.4 14.4 1.6e-19 70.5 14.4 1.3 1 0 0 1 1 1 1 BAR domain of APPL family PH PF00169.29 OAP61810.1 - 3.2e-13 50.1 0.2 1e-12 48.5 0.2 2.0 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 OAP61810.1 - 0.014 15.8 0.5 0.085 13.3 0.3 2.5 2 0 0 2 2 2 0 Pleckstrin homology domain PH_13 PF16652.5 OAP61810.1 - 0.023 14.5 0.4 0.093 12.5 0.0 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain ANAPC9 PF12856.7 OAP61810.1 - 0.025 14.8 1.0 0.063 13.5 1.0 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 9 Ribosomal_L37ae PF01780.19 OAP61810.1 - 0.23 11.6 0.5 5 7.3 0.0 2.4 2 0 0 2 2 2 0 Ribosomal L37ae protein family DUF948 PF06103.11 OAP61810.1 - 2.2 8.6 4.3 29 5.0 0.1 2.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Phage_GP20 PF06810.11 OAP61810.1 - 3.5 7.4 13.8 2.8 7.8 1.8 2.6 2 0 0 2 2 2 0 Phage minor structural protein GP20 RRM_1 PF00076.22 OAP61811.1 - 1.1e-08 34.8 0.0 2.9e-08 33.4 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OAP61811.1 - 0.039 13.6 0.1 0.067 12.8 0.1 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Autophagy_act_C PF03987.15 OAP61812.1 - 1.1e-13 51.5 0.1 2.1e-13 50.6 0.1 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Haem_degrading PF03928.14 OAP61813.1 - 1.8e-34 118.4 0.3 2.2e-34 118.1 0.3 1.1 1 0 0 1 1 1 1 Haem-degrading Varsurf_PPLC PF03490.13 OAP61813.1 - 0.13 12.2 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 Variant-surface-glycoprotein phospholipase C Rotamase PF00639.21 OAP61815.1 - 2.3e-24 86.1 0.0 3.8e-24 85.5 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 OAP61815.1 - 3.6e-16 59.8 0.0 4.7e-16 59.4 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.26 OAP61815.1 - 2e-08 34.1 3.1 2e-08 34.1 3.1 1.6 2 0 0 2 2 2 1 WW domain Rotamase_2 PF13145.6 OAP61815.1 - 1.4e-05 25.9 0.0 1.9e-05 25.5 0.0 1.4 1 1 0 1 1 1 1 PPIC-type PPIASE domain MRI PF15325.6 OAP61815.1 - 0.059 14.5 0.9 0.09 13.9 0.6 1.4 1 1 0 1 1 1 0 Modulator of retrovirus infection Ribosomal_L14 PF00238.19 OAP61816.1 - 6.6e-48 161.8 1.9 7.3e-48 161.7 1.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Phage_antitermQ PF06530.12 OAP61816.1 - 0.11 12.4 0.1 0.2 11.6 0.1 1.4 1 0 0 1 1 1 0 Phage antitermination protein Q SET PF00856.28 OAP61817.1 - 2.6e-10 40.9 0.0 3.7e-08 33.9 0.0 2.5 2 0 0 2 2 2 2 SET domain Pyocin_S PF06958.12 OAP61817.1 - 0.035 14.6 0.1 0.035 14.6 0.1 2.4 2 1 0 2 2 2 0 S-type Pyocin adh_short_C2 PF13561.6 OAP61818.1 - 1.1e-29 103.7 0.1 4.2e-28 98.5 0.1 2.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP61818.1 - 1.1e-22 80.5 0.0 1.9e-22 79.7 0.0 1.3 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAP61818.1 - 0.00058 19.8 0.0 0.0011 18.9 0.0 1.3 1 0 0 1 1 1 1 KR domain MRP-L46 PF11788.8 OAP61819.1 - 1.1e-28 100.3 0.2 3.1e-28 98.9 0.0 1.9 2 0 0 2 2 2 1 39S mitochondrial ribosomal protein L46 Exo_endo_phos PF03372.23 OAP61820.1 - 1.2e-05 24.9 0.0 2.3e-05 24.1 0.0 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SNF5 PF04855.12 OAP61821.1 - 1.6e-63 214.7 0.2 1.9e-62 211.2 0.2 2.1 1 1 0 1 1 1 1 SNF5 / SMARCB1 / INI1 INO80_Ies4 PF08193.11 OAP61821.1 - 0.13 12.3 5.6 0.033 14.2 1.3 2.1 2 0 0 2 2 2 0 INO80 complex subunit Ies4 Peptidase_M24 PF00557.24 OAP61822.1 - 2.2e-07 30.8 0.0 3.4e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 AP3D1 PF06375.11 OAP61822.1 - 0.0069 16.6 2.7 0.0069 16.6 2.7 1.6 2 0 0 2 2 2 1 AP-3 complex subunit delta-1 OAD_gamma PF04277.13 OAP61822.1 - 0.16 12.6 8.5 0.11 13.0 3.9 2.5 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain DUF3246 PF11596.8 OAP61822.1 - 0.18 11.2 4.5 0.34 10.3 4.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) PHD PF00628.29 OAP61823.1 - 1.5e-17 63.2 14.0 1.6e-11 43.9 7.8 2.4 2 0 0 2 2 2 2 PHD-finger zf-PHD-like PF15446.6 OAP61823.1 - 0.014 15.0 7.0 0.019 14.6 3.0 2.5 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain PHD_2 PF13831.6 OAP61823.1 - 0.09 12.4 11.0 0.012 15.2 3.8 2.9 3 0 0 3 3 3 0 PHD-finger C1_1 PF00130.22 OAP61823.1 - 0.53 10.2 11.2 4.5 7.2 4.0 2.3 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Ras PF00071.22 OAP61824.1 - 7.8e-53 178.4 0.0 9.4e-53 178.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAP61824.1 - 1.1e-18 67.5 0.0 1.6e-18 67.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAP61824.1 - 1.5e-06 27.8 0.0 2.2e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RRM_1 PF00076.22 OAP61825.1 - 2.3e-36 123.4 0.0 4.2e-11 42.5 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OAP61825.1 - 2e-14 53.2 0.0 0.0041 16.9 0.0 4.3 4 0 0 4 4 4 4 Occluded RNA-recognition motif RRM PF10378.9 OAP61825.1 - 1.6e-07 30.9 10.7 8.9e-07 28.5 10.5 2.5 1 1 0 1 1 1 1 Putative RRM domain DUF4523 PF15023.6 OAP61825.1 - 7.6e-06 25.8 0.0 0.082 12.7 0.0 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF4523) RRM_7 PF16367.5 OAP61825.1 - 1.6e-05 24.9 0.0 0.059 13.5 0.0 3.6 3 0 0 3 3 3 1 RNA recognition motif RRM_3 PF08777.11 OAP61825.1 - 0.00021 21.3 0.0 0.2 11.7 0.1 3.1 3 0 0 3 3 3 2 RNA binding motif RRM_Rrp7 PF17799.1 OAP61825.1 - 0.027 14.3 0.0 1.6 8.5 0.0 3.3 2 1 2 4 4 4 0 Rrp7 RRM-like N-terminal domain RNA_bind PF08675.11 OAP61825.1 - 0.12 12.4 0.4 0.64 10.1 0.0 2.4 3 0 0 3 3 3 0 RNA binding domain tRNA-synt_2 PF00152.20 OAP61826.1 - 8.4e-87 291.2 0.0 2.2e-86 289.8 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 OAP61826.1 - 4.5e-09 36.2 0.0 8.6e-09 35.3 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA_anti_2 PF13742.6 OAP61826.1 - 0.062 13.5 0.0 0.21 11.8 0.0 1.9 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain DUF4539 PF15072.6 OAP61826.1 - 0.13 12.3 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4539) Lectin_leg-like PF03388.13 OAP61827.1 - 1.5e-27 96.4 0.2 3.3e-27 95.3 0.0 1.5 2 0 0 2 2 2 1 Legume-like lectin family m_DGTX_Dc1a_b_c PF17491.2 OAP61827.1 - 0.019 15.6 0.8 0.039 14.6 0.8 1.4 1 0 0 1 1 1 0 Spider Toxins mu-diguetoxin-1 a, b and c Baculo_PEP_C PF04513.12 OAP61827.1 - 0.071 13.1 1.6 0.3 11.1 1.5 1.8 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Prefoldin_2 PF01920.20 OAP61827.1 - 0.1 12.5 0.5 13 5.8 0.1 2.4 2 0 0 2 2 2 0 Prefoldin subunit ABC_tran_CTD PF16326.5 OAP61827.1 - 0.17 12.2 1.6 8.9 6.6 0.0 2.9 1 1 2 3 3 3 0 ABC transporter C-terminal domain DUF4094 PF13334.6 OAP61827.1 - 6.7 7.2 6.4 0.72 10.3 0.8 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4094) Alg6_Alg8 PF03155.15 OAP61828.1 - 1.1e-175 585.3 28.3 1.2e-175 585.1 28.3 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family WAC_Acf1_DNA_bd PF10537.9 OAP61829.1 - 2.6e-37 127.4 0.0 8e-37 125.8 0.0 1.9 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal WSD PF15613.6 OAP61829.1 - 1.7e-22 79.7 0.2 1.7e-22 79.7 0.2 2.8 3 0 0 3 3 3 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DDT PF02791.17 OAP61829.1 - 4.2e-16 59.0 4.4 7.8e-16 58.1 4.4 1.4 1 0 0 1 1 1 1 DDT domain WHIM1 PF15612.6 OAP61829.1 - 2.9e-06 26.6 0.0 6.9e-06 25.5 0.0 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 Dynamin_N PF00350.23 OAP61829.1 - 0.22 11.6 0.8 0.67 10.0 0.8 1.8 1 0 0 1 1 1 0 Dynamin family Arginase PF00491.21 OAP61830.1 - 1.3e-89 300.4 0.0 1.6e-89 300.1 0.0 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 OAP61830.1 - 0.012 15.9 0.1 0.019 15.2 0.1 1.2 1 0 0 1 1 1 0 UPF0489 domain ketoacyl-synt PF00109.26 OAP61831.1 - 4e-59 200.3 0.8 4.2e-58 196.9 0.1 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 OAP61831.1 - 2.2e-34 118.0 0.9 4.1e-34 117.1 0.9 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 OAP61831.1 - 1.7e-06 27.6 0.6 6.5e-05 22.4 0.1 2.4 2 0 0 2 2 2 1 Thiolase, N-terminal domain ACP_syn_III PF08545.10 OAP61831.1 - 0.011 15.5 2.6 2.7 7.9 0.1 3.3 2 1 1 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_C PF02803.18 OAP61831.1 - 0.014 15.0 3.3 0.23 11.1 0.3 3.1 2 2 1 3 3 3 0 Thiolase, C-terminal domain SCA7 PF08313.12 OAP61832.1 - 2.3e-31 107.5 0.3 2.3e-31 107.5 0.3 2.2 3 0 0 3 3 3 1 SCA7, zinc-binding domain CDC45 PF02724.14 OAP61832.1 - 0.0084 14.5 11.1 0.011 14.1 11.1 1.1 1 0 0 1 1 1 1 CDC45-like protein DUF2897 PF11446.8 OAP61832.1 - 0.049 13.5 0.3 0.049 13.5 0.3 4.2 4 2 1 5 5 5 0 Protein of unknown function (DUF2897) OrsD PF12013.8 OAP61832.1 - 0.068 13.6 0.7 0.068 13.6 0.7 1.9 2 0 0 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D DUF3537 PF12056.8 OAP61832.1 - 0.07 11.9 1.2 0.1 11.4 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3537) TLP-20 PF06088.11 OAP61832.1 - 1.5 8.7 8.0 2.7 7.8 8.0 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Presenilin PF01080.17 OAP61832.1 - 4.9 5.8 6.2 7.5 5.2 6.2 1.2 1 0 0 1 1 1 0 Presenilin mRNA_cap_enzyme PF01331.19 OAP61833.1 - 1.6e-54 184.7 1.2 2.2e-54 184.2 1.2 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 OAP61833.1 - 8.9e-30 103.5 0.6 4.7e-29 101.2 0.4 2.0 2 0 0 2 2 2 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.21 OAP61833.1 - 7.6e-10 38.8 0.1 0.00019 21.1 0.0 2.3 1 1 1 2 2 2 2 ATP dependent DNA ligase domain RNA_ligase PF09414.10 OAP61833.1 - 5.5e-05 23.5 0.7 0.0001 22.6 0.1 1.7 2 0 0 2 2 2 1 RNA ligase GrpB PF04229.14 OAP61833.1 - 0.0018 18.5 3.2 0.0018 18.5 3.2 2.0 2 0 0 2 2 2 1 GrpB protein Fungal_trans PF04082.18 OAP61834.1 - 2.2e-15 56.4 0.7 5.3e-15 55.2 0.7 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP61834.1 - 1.7e-07 31.2 7.6 3.2e-07 30.3 7.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NinF PF05810.12 OAP61834.1 - 0.23 11.3 1.2 0.59 10.0 1.2 1.6 1 0 0 1 1 1 0 NinF protein adh_short PF00106.25 OAP61835.1 - 1e-17 64.2 0.1 3.3e-14 52.8 0.1 2.2 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAP61835.1 - 2.1e-07 30.7 0.1 1.3e-05 24.9 0.0 2.3 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP61835.1 - 0.00096 19.1 0.1 0.0018 18.2 0.1 1.4 1 0 0 1 1 1 1 KR domain HEAT PF02985.22 OAP61836.1 - 0.0014 18.7 1.6 0.82 10.1 0.0 5.1 4 0 0 4 4 4 1 HEAT repeat EH_Signature PF15611.6 OAP61836.1 - 5.2 6.4 10.9 0.2 11.0 3.5 2.5 4 0 0 4 4 4 0 EH_Signature domain CFEM PF05730.11 OAP61838.1 - 4e-10 39.7 4.2 9.1e-10 38.5 4.2 1.6 1 0 0 1 1 1 1 CFEM domain FoP_duplication PF13865.6 OAP61838.1 - 4.5 7.9 7.4 32 5.2 5.7 2.3 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 BSD PF03909.17 OAP61839.1 - 2.9e-18 65.6 2.5 7.1e-18 64.4 0.9 2.3 2 0 0 2 2 2 1 BSD domain Suf PF05843.14 OAP61839.1 - 0.02 14.9 0.9 0.02 14.9 0.9 1.7 3 0 0 3 3 3 0 Suppressor of forked protein (Suf) DUF327 PF03885.13 OAP61839.1 - 0.21 11.6 3.3 1.3 9.0 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF327) Med3 PF11593.8 OAP61839.1 - 0.39 9.8 4.5 10 5.2 0.0 2.2 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal DNA_ligase_A_M PF01068.21 OAP61841.1 - 7.7e-60 202.0 0.8 3e-57 193.6 0.8 2.3 1 1 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 OAP61841.1 - 1.1e-44 152.7 0.1 2.2e-44 151.8 0.1 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 OAP61841.1 - 5.4e-28 97.5 0.0 2.5e-27 95.4 0.0 2.3 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region Adeno_E1B_55K_N PF04623.12 OAP61841.1 - 0.079 13.7 0.0 0.25 12.1 0.0 1.9 1 0 0 1 1 1 0 Adenovirus E1B protein N-terminus Ank_2 PF12796.7 OAP61842.1 - 7.8e-60 199.4 6.1 6.4e-10 39.5 0.0 9.5 5 2 5 11 11 11 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAP61842.1 - 2.5e-44 149.1 8.9 9e-08 32.5 0.0 10.5 8 2 2 11 11 11 8 Ankyrin repeats (many copies) Ank PF00023.30 OAP61842.1 - 4.4e-32 109.1 11.2 0.018 15.4 0.0 16.7 15 2 0 15 15 15 6 Ankyrin repeat Ank_3 PF13606.6 OAP61842.1 - 2.4e-31 104.3 16.6 0.15 12.7 0.0 16.0 17 0 0 17 17 17 7 Ankyrin repeat Ank_5 PF13857.6 OAP61842.1 - 2.7e-25 88.1 12.3 0.002 18.4 0.1 10.7 7 3 3 10 10 10 7 Ankyrin repeats (many copies) ZZ PF00569.17 OAP61842.1 - 0.0027 17.5 6.4 0.0061 16.3 6.4 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type C1_2 PF03107.16 OAP61842.1 - 0.34 11.3 9.1 0.89 9.9 9.1 1.7 1 0 0 1 1 1 0 C1 domain Peptidase_S8 PF00082.22 OAP61844.1 - 2.1e-16 60.1 0.0 3.7e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 Subtilase family Ank_2 PF12796.7 OAP61844.1 - 3.3e-09 37.2 0.0 0.00045 20.7 0.0 2.8 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OAP61844.1 - 5.2e-06 26.4 0.0 0.41 11.3 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 OAP61844.1 - 1e-05 26.0 0.1 0.1 13.2 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 OAP61844.1 - 7.4e-05 23.0 0.0 0.052 14.0 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat UBM PF14377.6 OAP61844.1 - 0.02 14.4 0.9 0.054 13.0 0.9 1.7 1 0 0 1 1 1 0 Ubiquitin binding region RQC PF09382.10 OAP61846.1 - 1.8e-23 82.5 0.0 4.2e-23 81.3 0.0 1.6 1 0 0 1 1 1 1 RQC domain DEAD PF00270.29 OAP61846.1 - 8.5e-23 81.0 0.4 3.4e-22 79.0 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAP61846.1 - 3.4e-22 78.9 0.7 8.2e-18 64.8 0.0 3.7 4 0 0 4 4 4 2 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 OAP61846.1 - 4.7e-16 59.3 7.0 1.4e-15 57.7 7.0 1.9 1 0 0 1 1 1 1 RecQ zinc-binding HRDC PF00570.23 OAP61846.1 - 0.0021 18.0 0.0 0.0074 16.2 0.0 1.9 1 0 0 1 1 1 1 HRDC domain DUF4600 PF15372.6 OAP61846.1 - 4.3 7.8 6.6 62 4.0 6.6 2.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4600) Kelch_4 PF13418.6 OAP61847.1 - 1e-30 105.5 8.9 1.6e-08 34.4 0.0 6.3 5 1 0 5 5 5 5 Galactose oxidase, central domain DUF4110 PF13422.6 OAP61847.1 - 1.7e-29 101.7 3.8 1.7e-29 101.7 3.8 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4110) Kelch_3 PF13415.6 OAP61847.1 - 1.4e-25 89.0 14.5 1e-09 38.4 0.1 6.7 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_5 PF13854.6 OAP61847.1 - 1.5e-20 72.7 6.4 2.1e-06 27.6 0.0 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 OAP61847.1 - 1e-16 60.5 5.7 0.00017 21.7 0.0 5.9 5 1 1 6 6 6 4 Kelch motif Kelch_1 PF01344.25 OAP61847.1 - 3.1e-15 55.5 5.6 2.2e-08 33.5 0.0 5.4 5 1 0 5 5 5 4 Kelch motif Kelch_2 PF07646.15 OAP61847.1 - 1.5e-13 50.1 14.8 0.00011 22.0 0.0 6.3 6 1 0 6 6 6 4 Kelch motif PI3K_1B_p101 PF10486.9 OAP61847.1 - 0.84 7.3 4.0 1.3 6.7 4.0 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit BUD22 PF09073.10 OAP61847.1 - 3.4 6.9 16.8 0.73 9.1 5.3 2.3 2 0 0 2 2 2 0 BUD22 OAD_gamma PF04277.13 OAP61847.1 - 6.7 7.4 5.9 30 5.3 5.9 2.1 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Gpi16 PF04113.14 OAP61848.1 - 9.1e-236 783.7 0.0 1.1e-235 783.4 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component Coagulin PF02035.15 OAP61848.1 - 0.15 12.0 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 Coagulin LUC7 PF03194.15 OAP61849.1 - 2.2e-70 237.2 0.5 2.6e-70 236.9 0.5 1.0 1 0 0 1 1 1 1 LUC7 N_terminus MCPsignal PF00015.21 OAP61849.1 - 0.038 13.8 0.0 0.059 13.2 0.0 1.3 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain GRP PF07172.11 OAP61849.1 - 1.9 9.2 39.0 3.9 8.2 39.0 1.5 1 0 0 1 1 1 0 Glycine rich protein family Pkinase PF00069.25 OAP61850.1 - 5.9e-66 222.5 0.1 1.7e-65 221.0 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP61850.1 - 4.8e-44 150.6 0.0 7.4e-44 150.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAP61850.1 - 1.4e-09 37.7 0.0 4.7e-08 32.7 0.0 2.6 3 0 0 3 3 3 1 Kinase-like Haspin_kinase PF12330.8 OAP61850.1 - 7.5e-06 25.1 0.0 7.5e-06 25.1 0.0 2.4 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 OAP61850.1 - 0.023 14.0 0.0 0.098 12.0 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OAP61850.1 - 0.042 13.8 4.7 0.56 10.1 0.3 3.1 2 1 1 3 3 3 0 Phosphotransferase enzyme family DEAD PF00270.29 OAP61851.1 - 4.8e-47 160.0 0.0 1.5e-46 158.4 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAP61851.1 - 2.3e-29 102.0 0.1 1.2e-28 99.7 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAP61851.1 - 0.014 15.4 0.0 0.035 14.1 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit PRAI PF00697.22 OAP61851.1 - 0.13 12.0 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase DUF2986 PF11661.8 OAP61851.1 - 0.41 11.2 6.7 0.063 13.8 1.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2986) Spc7_N PF15402.6 OAP61852.1 - 4.2e-258 859.3 69.0 4.2e-258 859.3 69.0 2.3 2 0 0 2 2 2 1 N-terminus of kinetochore NMS complex subunit Spc7 Spc7 PF08317.11 OAP61852.1 - 4.8e-102 341.0 8.0 4.8e-102 341.0 8.0 1.6 2 0 0 2 2 2 1 Spc7 kinetochore protein Spc7_C2 PF15577.6 OAP61852.1 - 5.4e-09 36.0 0.1 1e-08 35.1 0.1 1.5 1 0 0 1 1 1 1 Spc7_C2 Exonuc_VII_L PF02601.15 OAP61852.1 - 9.3 5.7 10.2 1.7 8.2 4.9 2.2 2 0 0 2 2 2 0 Exonuclease VII, large subunit Ribosomal_S17_N PF16205.5 OAP61853.1 - 1.7e-33 114.8 0.2 3.1e-33 114.0 0.2 1.5 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 OAP61853.1 - 7.5e-26 90.0 0.6 1.3e-25 89.3 0.2 1.6 2 0 0 2 2 2 1 Ribosomal protein S17 Oxidored_FMN PF00724.20 OAP61854.1 - 1.4e-41 142.9 0.0 2e-41 142.4 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family FMN_dh PF01070.18 OAP61854.1 - 0.0083 15.2 0.0 0.019 14.0 0.0 1.6 2 0 0 2 2 2 1 FMN-dependent dehydrogenase WD40 PF00400.32 OAP61855.1 - 6.1e-06 26.9 0.5 0.18 12.7 0.1 5.8 6 0 0 6 6 6 1 WD domain, G-beta repeat Glyco_hydro_2 PF00703.21 OAP61857.1 - 2.9e-11 44.0 0.0 7e-11 42.8 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Mannosidase_ig PF17786.1 OAP61857.1 - 6.3e-08 33.1 0.0 1.7e-07 31.7 0.0 1.8 1 0 0 1 1 1 1 Mannosidase Ig/CBM-like domain Ig_mannosidase PF17753.1 OAP61857.1 - 4.3e-05 23.2 0.0 0.00012 21.8 0.0 1.8 1 0 0 1 1 1 1 Ig-fold domain Glyco_hydro_2_N PF02837.18 OAP61857.1 - 0.035 14.0 0.0 0.059 13.3 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, sugar binding domain Ig_GlcNase PF18368.1 OAP61857.1 - 0.042 14.0 0.5 0.26 11.4 0.0 2.3 2 0 0 2 2 2 0 Exo-beta-D-glucosaminidase Ig-fold domain Fungal_trans PF04082.18 OAP61858.1 - 1e-12 47.7 0.0 2.1e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP61858.1 - 5.6e-08 32.8 15.1 8.7e-08 32.2 15.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain His_Phos_2 PF00328.22 OAP61859.1 - 8.7e-66 222.8 0.0 1.2e-65 222.4 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) GMC_oxred_N PF00732.19 OAP61859.1 - 3.5e-46 157.9 0.0 5.8e-46 157.2 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAP61859.1 - 1.2e-38 132.9 0.1 2.5e-38 131.8 0.1 1.6 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 OAP61859.1 - 0.045 14.0 0.1 0.17 12.1 0.1 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain MFS_1 PF07690.16 OAP61860.1 - 3.4e-26 92.0 48.7 3.4e-26 92.0 48.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily FGGY_C PF02782.16 OAP61861.1 - 4.4e-72 242.0 1.1 7.3e-72 241.3 1.1 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 OAP61861.1 - 1.2e-69 234.6 0.0 1.6e-69 234.2 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.20 OAP61861.1 - 0.0075 15.8 0.3 1 8.8 0.0 2.2 2 0 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family MIP PF00230.20 OAP61862.1 - 3.6e-56 190.4 6.1 4.6e-56 190.1 6.1 1.1 1 0 0 1 1 1 1 Major intrinsic protein Glyco_hydro_16 PF00722.21 OAP61863.1 - 3.4e-07 29.9 2.7 4.6e-07 29.5 0.0 2.6 3 0 0 3 3 3 1 Glycosyl hydrolases family 16 Zn_clus PF00172.18 OAP61864.1 - 4.5e-05 23.5 8.6 4.5e-05 23.5 8.6 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAP61864.1 - 0.00011 21.4 0.4 0.00022 20.4 0.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain TMEM171 PF15471.6 OAP61864.1 - 2 7.3 4.9 3.8 6.4 3.0 2.1 2 0 0 2 2 2 0 Transmembrane protein family 171 MFS_1 PF07690.16 OAP61865.1 - 4e-43 147.7 49.4 4e-43 147.7 49.4 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 OAP61865.1 - 4.3e-11 42.0 17.1 1.1e-10 40.6 17.2 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Plant_vir_prot PF01307.17 OAP61865.1 - 0.14 12.4 0.2 0.86 9.9 0.0 2.4 2 0 0 2 2 2 0 Plant viral movement protein DUF1269 PF06897.12 OAP61865.1 - 9.1 6.6 7.6 0.38 11.1 1.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1269) ILVD_EDD PF00920.21 OAP61866.1 - 6.4e-211 701.5 1.2 7.3e-211 701.3 1.2 1.0 1 0 0 1 1 1 1 Dehydratase family Cyclase PF04199.13 OAP61867.1 - 5.9e-14 52.5 0.0 1.2e-13 51.5 0.0 1.5 1 1 0 1 1 1 1 Putative cyclase Vps54 PF07928.12 OAP61868.1 - 9.3e-53 178.3 0.3 9.3e-53 178.3 0.3 2.4 3 0 0 3 3 3 1 Vps54-like protein Vps54_N PF10475.9 OAP61868.1 - 8.1e-06 25.3 1.4 8.1e-06 25.3 1.4 2.4 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex DUF3510 PF12022.8 OAP61868.1 - 0.02 15.3 1.0 0.72 10.2 0.1 3.5 2 1 1 3 3 3 0 Domain of unknown function (DUF3510) Sec8_exocyst PF04048.14 OAP61868.1 - 0.022 14.7 1.4 0.074 12.9 1.4 1.9 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain LUC7 PF03194.15 OAP61868.1 - 1.4 8.5 8.2 1.4 8.5 5.9 2.0 2 1 0 2 2 2 0 LUC7 N_terminus HET PF06985.11 OAP61870.1 - 6.2e-10 39.6 0.9 7.9e-07 29.5 0.0 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.16 OAP61871.1 - 6.4e-36 124.0 30.7 6.4e-36 124.0 30.7 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily MCM PF00493.23 OAP61872.1 - 2e-105 350.8 0.2 5.2e-105 349.5 0.0 1.7 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 OAP61872.1 - 4.8e-36 123.4 0.3 1.2e-35 122.1 0.3 1.6 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 OAP61872.1 - 6.8e-27 93.7 1.9 1.7e-26 92.5 1.9 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 OAP61872.1 - 6.1e-16 58.9 0.5 1.3e-15 57.8 0.5 1.6 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 OAP61872.1 - 1.3e-06 28.0 0.0 0.00026 20.4 0.0 2.3 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 OAP61872.1 - 2.5e-05 24.3 0.0 5.8e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 OAP61872.1 - 0.0003 20.6 0.1 0.0013 18.6 0.0 2.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 OAP61872.1 - 0.03 14.0 0.0 0.97 9.1 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA PF00004.29 OAP61872.1 - 0.11 12.9 0.2 0.54 10.7 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Velvet PF11754.8 OAP61873.1 - 0.00025 21.1 0.0 0.00067 19.7 0.0 1.6 2 0 0 2 2 2 1 Velvet factor Pkinase PF00069.25 OAP61874.1 - 9.5e-44 149.7 0.0 1e-40 139.8 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAP61874.1 - 1.9e-24 86.3 0.0 3.5e-24 85.5 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAP61874.1 - 0.0019 17.1 0.0 0.0028 16.5 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OAP61874.1 - 0.056 12.8 0.0 0.09 12.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OAP61874.1 - 0.18 11.1 0.1 0.62 9.3 0.1 1.8 1 1 0 1 1 1 0 Kinase-like PhyH PF05721.13 OAP61875.1 - 1.3e-24 87.6 0.3 2e-24 87.1 0.3 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) ADH_zinc_N PF00107.26 OAP61876.1 - 7.4e-22 77.7 0.1 1.5e-21 76.7 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAP61876.1 - 1.3e-20 73.3 0.8 3.1e-20 72.1 0.1 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 OAP61876.1 - 6.4e-05 24.0 0.0 0.00012 23.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 OAP61876.1 - 8.8e-05 22.1 0.5 0.00016 21.3 0.5 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 OAP61876.1 - 0.037 13.3 5.5 0.083 12.2 5.5 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DLH PF01738.18 OAP61878.1 - 1.1e-22 80.7 0.0 1.4e-22 80.4 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family LIDHydrolase PF10230.9 OAP61878.1 - 0.0036 16.9 0.0 0.0046 16.5 0.0 1.1 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Peptidase_S15 PF02129.18 OAP61878.1 - 0.087 12.4 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 OAP61878.1 - 0.16 11.4 0.0 0.46 9.9 0.0 1.7 2 0 0 2 2 2 0 Prolyl oligopeptidase family Acyl-CoA_dh_1 PF00441.24 OAP61879.1 - 9.9e-37 126.4 0.9 2.1e-36 125.4 0.4 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 OAP61879.1 - 6.5e-17 61.5 0.1 1.5e-16 60.4 0.1 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 OAP61879.1 - 3.7e-11 43.4 0.0 6.5e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 OAP61879.1 - 1.7e-08 35.1 0.0 9.4e-08 32.7 0.0 2.2 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain HpaB_N PF11794.8 OAP61879.1 - 0.0039 16.9 0.1 0.01 15.5 0.1 1.6 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Tai4 PF16695.5 OAP61880.1 - 7.3 7.2 5.4 1.4e+02 3.1 0.0 5.0 5 0 0 5 5 5 0 Type VI secretion system (T6SS), amidase immunity protein CAP_N PF01213.19 OAP61881.1 - 0.089 12.3 7.8 1 8.8 7.6 2.2 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Metallophos PF00149.28 OAP61882.1 - 1.6e-10 41.9 2.0 1.6e-10 41.9 2.0 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase 5_nucleotid_C PF02872.18 OAP61882.1 - 0.0019 18.4 0.0 0.0037 17.5 0.0 1.4 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain p450 PF00067.22 OAP61883.1 - 5.7e-49 167.1 0.0 1e-48 166.3 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 Aminotran_1_2 PF00155.21 OAP61883.1 - 4.1e-08 32.8 0.0 1.6e-07 30.9 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class I and II Methyltransf_23 PF13489.6 OAP61884.1 - 8.6e-17 61.5 0.0 1.3e-16 60.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAP61884.1 - 2e-08 34.8 0.0 6.4e-08 33.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAP61884.1 - 2.4e-06 28.2 0.0 2e-05 25.2 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAP61884.1 - 3.2e-06 27.7 0.0 7.1e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAP61884.1 - 4.4e-05 23.3 0.0 0.25 11.1 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain FtsJ PF01728.19 OAP61884.1 - 0.0087 16.2 0.0 0.013 15.6 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase PrmA PF06325.13 OAP61884.1 - 0.037 13.4 0.0 0.055 12.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.17 OAP61884.1 - 0.037 13.5 0.0 0.072 12.6 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase MTS PF05175.14 OAP61884.1 - 0.047 13.2 0.0 0.083 12.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain EspA PF03433.13 OAP61884.1 - 0.22 11.3 0.0 0.33 10.8 0.0 1.2 1 0 0 1 1 1 0 EspA-like secreted protein LCCL PF03815.19 OAP61885.1 - 9.8e-21 73.7 0.1 1.6e-20 73.0 0.1 1.3 1 0 0 1 1 1 1 LCCL domain AMP-binding PF00501.28 OAP61886.1 - 1.4e-84 284.1 0.0 1.7e-84 283.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Cys_Met_Meta_PP PF01053.20 OAP61887.1 - 5.7e-147 489.2 0.0 6.5e-147 489.0 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 OAP61887.1 - 8e-10 38.4 0.0 1.2e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 OAP61887.1 - 4.5e-08 32.8 0.1 8e-08 32.0 0.1 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 OAP61887.1 - 6.9e-05 22.0 0.2 0.00011 21.2 0.2 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 OAP61887.1 - 0.00048 19.5 0.0 0.00079 18.8 0.0 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase SepSecS PF05889.13 OAP61887.1 - 0.0016 17.3 0.0 0.0021 16.8 0.0 1.2 1 0 0 1 1 1 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Met_gamma_lyase PF06838.11 OAP61887.1 - 0.025 13.1 0.0 0.035 12.6 0.0 1.2 1 0 0 1 1 1 0 Methionine gamma-lyase MFS_1 PF07690.16 OAP61888.1 - 5.6e-50 170.3 32.7 1.1e-36 126.5 15.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 OAP61888.1 - 7.9e-09 34.6 25.0 1e-06 27.6 2.5 2.6 2 1 1 3 3 3 2 MFS/sugar transport protein OATP PF03137.20 OAP61888.1 - 2.7e-06 26.0 2.4 0.0007 18.0 1.6 2.5 2 1 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.24 OAP61888.1 - 9.9e-05 21.4 10.8 9.9e-05 21.4 10.8 2.7 2 1 0 2 2 2 1 Sugar (and other) transporter MARVEL PF01284.23 OAP61889.1 - 9.7e-19 67.8 17.0 1.1e-18 67.6 17.0 1.1 1 0 0 1 1 1 1 Membrane-associating domain UL45 PF05473.12 OAP61889.1 - 0.14 11.8 0.7 0.25 10.9 0.7 1.4 1 0 0 1 1 1 0 UL45 protein, carbohydrate-binding C-type lectin-like DUF1440 PF07274.12 OAP61889.1 - 0.62 10.4 6.2 0.23 11.8 3.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1440) DUF202 PF02656.15 OAP61889.1 - 1.7 9.1 13.6 0.12 12.8 3.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF202) Fungal_trans_2 PF11951.8 OAP61890.1 - 7.6e-10 38.1 0.3 2e-08 33.5 0.0 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain EF-hand_4 PF12763.7 OAP61891.1 - 1.9e-33 114.5 0.0 9.1e-13 48.1 0.0 3.5 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 OAP61891.1 - 1.3e-08 33.7 0.5 0.28 10.8 0.0 5.5 5 0 0 5 5 5 2 EF hand EF-hand_7 PF13499.6 OAP61891.1 - 5.7e-08 33.1 0.0 0.00047 20.6 0.0 4.2 5 0 0 5 5 3 1 EF-hand domain pair Spc7 PF08317.11 OAP61891.1 - 0.00026 20.0 37.8 0.0015 17.5 27.4 2.1 1 1 1 2 2 2 2 Spc7 kinetochore protein EF-hand_6 PF13405.6 OAP61891.1 - 0.0012 18.6 0.9 27 5.0 0.2 5.0 5 0 0 5 5 5 0 EF-hand domain DUF724 PF05266.14 OAP61891.1 - 0.0014 18.5 10.9 0.0014 18.5 10.9 3.1 1 1 2 3 3 3 1 Protein of unknown function (DUF724) UBA PF00627.31 OAP61891.1 - 0.0028 17.5 0.0 0.0058 16.5 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain Macoilin PF09726.9 OAP61891.1 - 0.0083 14.8 26.6 0.016 13.8 26.6 1.3 1 0 0 1 1 1 1 Macoilin family PRKG1_interact PF15898.5 OAP61891.1 - 0.015 16.2 12.0 0.015 16.2 12.0 3.8 1 1 2 3 3 3 0 cGMP-dependent protein kinase interacting domain EF-hand_8 PF13833.6 OAP61891.1 - 0.13 12.1 0.1 32 4.5 0.0 3.5 4 0 0 4 4 4 0 EF-hand domain pair DUF3854 PF12965.7 OAP61891.1 - 0.21 11.6 1.7 0.47 10.4 1.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3854) GAS PF13851.6 OAP61891.1 - 0.23 10.8 38.2 1.2 8.5 20.0 2.5 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF3584 PF12128.8 OAP61891.1 - 0.38 8.2 33.1 0.61 7.5 33.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Lebercilin PF15619.6 OAP61891.1 - 0.4 10.3 39.6 0.89 9.2 38.9 1.8 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Mating_N PF12731.7 OAP61891.1 - 0.41 10.8 3.1 6.2 7.0 0.5 2.4 2 0 0 2 2 2 0 Mating-type protein beta 1 MbeD_MobD PF04899.12 OAP61891.1 - 0.46 10.6 20.2 0.25 11.5 3.8 4.0 3 1 2 5 5 3 0 MbeD/MobD like WEMBL PF05701.11 OAP61891.1 - 0.7 8.5 32.8 1.1 7.9 32.8 1.2 1 0 0 1 1 1 0 Weak chloroplast movement under blue light DUF4746 PF15928.5 OAP61891.1 - 1.2 8.4 15.7 1.1 8.7 13.9 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4746) Csm1_N PF18504.1 OAP61891.1 - 1.3 9.4 37.0 0.034 14.5 3.6 4.3 3 1 1 4 4 4 0 Csm1 N-terminal domain EzrA PF06160.12 OAP61891.1 - 1.5 6.9 25.7 2.2 6.3 25.7 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Golgin_A5 PF09787.9 OAP61891.1 - 1.9 7.9 38.6 1.1 8.7 20.8 2.2 1 1 1 2 2 2 0 Golgin subfamily A member 5 LPP PF04728.13 OAP61891.1 - 2.3 8.7 26.0 0.38 11.2 1.7 4.4 2 1 2 4 4 4 0 Lipoprotein leucine-zipper APG6_N PF17675.1 OAP61891.1 - 3.5 8.1 44.6 8.4 6.9 19.8 3.1 1 1 1 2 2 2 0 Apg6 coiled-coil region BRE1 PF08647.11 OAP61891.1 - 4.9 7.3 38.8 0.48 10.5 10.5 3.3 2 1 1 3 3 3 0 BRE1 E3 ubiquitin ligase CENP-F_leu_zip PF10473.9 OAP61891.1 - 6.3 6.8 41.3 0.33 11.0 21.9 3.1 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 THOC7 PF05615.13 OAP61891.1 - 9 6.6 39.0 15 5.9 7.5 3.6 1 1 2 3 3 3 0 Tho complex subunit 7 Tubulin PF00091.25 OAP61892.1 - 8.9e-67 225.1 0.0 1.3e-66 224.5 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 OAP61892.1 - 6e-51 171.9 0.2 1.1e-50 171.1 0.2 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 OAP61892.1 - 0.0016 18.2 0.0 0.0039 16.9 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain Pga1 PF10333.9 OAP61893.1 - 0.00084 19.2 0.0 0.0011 18.9 0.0 1.3 1 0 0 1 1 1 1 GPI-Mannosyltransferase II co-activator Dioxygenase_C PF00775.21 OAP61894.1 - 5.1e-47 159.7 0.0 7.9e-47 159.0 0.0 1.3 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 OAP61894.1 - 5.9e-27 93.3 0.2 1.2e-26 92.3 0.2 1.5 1 0 0 1 1 1 1 Catechol dioxygenase N terminus Fungal_trans PF04082.18 OAP61894.1 - 7.8e-08 31.7 0.0 1.5e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP61894.1 - 3.4e-05 23.9 16.0 5.8e-05 23.1 16.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CarboxypepD_reg PF13620.6 OAP61894.1 - 0.0034 17.6 0.0 0.0089 16.3 0.0 1.7 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain Methyltr_RsmB-F PF01189.17 OAP61895.1 - 1.3e-75 253.5 0.0 2.1e-75 252.8 0.0 1.4 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 OAP61895.1 - 1.8e-07 31.5 0.0 4.8e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF FtsJ PF01728.19 OAP61895.1 - 0.014 15.5 0.0 0.032 14.3 0.0 1.6 1 0 0 1 1 1 0 FtsJ-like methyltransferase Zn_clus PF00172.18 OAP61896.1 - 3.3e-08 33.5 9.3 8.4e-08 32.2 9.3 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MRG PF05712.13 OAP61896.1 - 0.13 11.5 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 MRG Glycogen_syn PF05693.13 OAP61897.1 - 0 1138.3 0.0 0 1138.1 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glyco_transf_4 PF13439.6 OAP61897.1 - 4.4e-05 23.5 0.1 8.5e-05 22.6 0.1 1.6 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 OAP61897.1 - 9.8e-05 22.0 0.0 0.022 14.3 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 OAP61897.1 - 0.00059 20.3 0.0 0.19 12.2 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 OAP61897.1 - 0.00063 20.2 0.0 0.0013 19.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Sulfatase PF00884.23 OAP61898.1 - 6e-64 216.4 1.4 7.7e-64 216.0 1.4 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 OAP61898.1 - 0.00056 19.6 0.1 0.0014 18.3 0.1 1.5 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4976 PF16347.5 OAP61898.1 - 0.00068 19.9 0.3 0.0016 18.7 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4976) DUF229 PF02995.17 OAP61898.1 - 0.11 11.1 0.0 0.34 9.5 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF229) polyprenyl_synt PF00348.17 OAP61899.1 - 1.5e-90 302.8 0.0 1.8e-90 302.5 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase XPA_C PF05181.12 OAP61900.1 - 8.6e-26 89.7 2.5 1.7e-25 88.7 2.5 1.5 1 0 0 1 1 1 1 XPA protein C-terminus XPA_N PF01286.18 OAP61900.1 - 4.2e-06 26.7 2.9 9.1e-06 25.6 2.9 1.5 1 0 0 1 1 1 1 XPA protein N-terminal ADD_DNMT3 PF17980.1 OAP61900.1 - 0.13 12.3 0.1 0.29 11.2 0.1 1.5 1 0 0 1 1 1 0 Cysteine rich ADD domain in DNMT3 YhfH PF14149.6 OAP61900.1 - 0.15 12.1 1.9 0.8 9.7 0.1 2.7 2 0 0 2 2 2 0 YhfH-like protein ArfGap PF01412.18 OAP61900.1 - 2 8.5 5.2 0.45 10.6 0.4 2.3 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf Striatin PF08232.12 OAP61901.1 - 4.1e-42 144.4 9.5 4.1e-42 144.4 9.5 1.8 2 0 0 2 2 2 1 Striatin family WD40 PF00400.32 OAP61901.1 - 6.3e-12 45.8 8.9 0.0021 18.8 0.1 5.7 6 1 0 6 6 6 4 WD domain, G-beta repeat 4HBT PF03061.22 OAP61904.1 - 1.9e-07 31.4 0.0 2.9e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily Sugar_tr PF00083.24 OAP61905.1 - 1.5e-61 208.7 13.0 8.5e-59 199.6 13.0 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP61905.1 - 9.4e-15 54.4 30.8 9.4e-15 54.4 30.8 2.9 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF3099 PF11298.8 OAP61905.1 - 0.89 9.7 4.4 12 6.2 0.5 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3099) Catalase PF00199.19 OAP61906.1 - 2.8e-06 26.7 0.0 2.2e-05 23.8 0.0 1.9 2 0 0 2 2 2 1 Catalase DUF3405 PF11885.8 OAP61907.1 - 4.2e-128 428.2 0.8 5.7e-128 427.8 0.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) OppC_N PF12911.7 OAP61907.1 - 6.3 6.9 5.5 0.7 9.9 0.6 1.9 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C Dynamin_N PF00350.23 OAP61908.1 - 5.9e-30 104.5 0.6 1.2e-29 103.5 0.0 1.9 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.20 OAP61908.1 - 3.3e-25 88.9 0.0 5.9e-25 88.1 0.0 1.4 1 0 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.23 OAP61908.1 - 0.00019 21.5 0.0 0.0011 19.0 0.0 2.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_21 PF13304.6 OAP61908.1 - 0.0032 17.3 0.3 0.056 13.2 0.0 2.7 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system TINF2_N PF14973.6 OAP61908.1 - 0.032 14.6 0.6 0.25 11.7 0.2 2.5 2 0 0 2 2 2 0 TERF1-interacting nuclear factor 2 N-terminus LST1 PF05083.13 OAP61908.1 - 0.043 14.1 1.1 0.11 12.8 1.1 1.6 1 0 0 1 1 1 0 LST-1 protein ABC_tran PF00005.27 OAP61908.1 - 0.071 13.6 0.1 0.54 10.8 0.0 2.5 2 1 0 2 2 2 0 ABC transporter AAA_15 PF13175.6 OAP61908.1 - 0.082 12.6 0.1 0.21 11.2 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.6 OAP61908.1 - 0.091 12.5 0.0 0.24 11.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AA_permease_2 PF13520.6 OAP61909.1 - 1.7e-89 300.6 35.1 2.1e-89 300.3 35.1 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAP61909.1 - 3.2e-18 65.6 28.7 4.3e-18 65.2 28.7 1.2 1 0 0 1 1 1 1 Amino acid permease Alpha-amylase PF00128.24 OAP61910.1 - 1.6e-15 57.5 0.4 1.3e-14 54.5 0.0 2.1 2 0 0 2 2 2 1 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.18 OAP61910.1 - 0.012 16.1 0.1 0.043 14.3 0.0 2.0 2 0 0 2 2 2 0 Alpha amylase, C-terminal all-beta domain FtsX PF02687.21 OAP61911.1 - 0.37 11.3 2.4 0.69 10.4 2.4 1.4 1 0 0 1 1 1 0 FtsX-like permease family Zn_clus PF00172.18 OAP61912.1 - 2.1e-08 34.1 7.7 3.4e-08 33.5 7.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 OAP61912.1 - 2e-05 23.6 0.0 3.5e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain RuvC PF02075.17 OAP61913.1 - 0.065 13.1 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Crossover junction endodeoxyribonuclease RuvC Hpre_diP_synt_I PF07456.11 OAP61913.1 - 2.5 8.1 10.1 12 5.9 6.2 2.5 2 1 0 2 2 2 0 Heptaprenyl diphosphate synthase component I NTP_transf_9 PF04248.12 OAP61914.1 - 1.8e-29 101.4 0.4 2.1e-29 101.2 0.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF427) DEAD PF00270.29 OAP61915.1 - 5.2e-40 137.1 0.7 8.2e-40 136.4 0.7 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAP61915.1 - 6.4e-31 107.0 0.1 5.3e-30 104.0 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAP61915.1 - 8.5e-08 32.4 0.0 2.1e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit OCRL_clath_bd PF16726.5 OAP61915.1 - 0.087 13.0 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 Inositol polyphosphate 5-phosphatase clathrin binding domain YoaP PF14268.6 OAP61915.1 - 0.11 12.0 0.0 0.32 10.5 0.0 1.7 1 0 0 1 1 1 0 YoaP-like GMC_oxred_N PF00732.19 OAP61916.1 - 1.7e-65 221.3 0.0 2.3e-65 220.9 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase SIR2 PF02146.17 OAP61916.1 - 6.1e-56 189.1 0.0 9.4e-56 188.5 0.0 1.3 1 0 0 1 1 1 1 Sir2 family GMC_oxred_C PF05199.13 OAP61916.1 - 9.8e-18 65.1 0.0 2.6e-17 63.7 0.0 1.7 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 OAP61916.1 - 0.005 15.9 0.1 0.0077 15.3 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein UPF0184 PF03670.13 OAP61916.1 - 0.19 12.1 0.0 0.39 11.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) SF-assemblin PF06705.11 OAP61916.1 - 0.26 10.6 0.7 0.39 10.0 0.7 1.2 1 0 0 1 1 1 0 SF-assemblin/beta giardin Hexokinase_2 PF03727.16 OAP61918.1 - 5.4e-84 281.4 0.0 7.8e-84 280.8 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 OAP61918.1 - 1.2e-74 250.5 0.0 2.5e-74 249.5 0.0 1.5 2 0 0 2 2 2 1 Hexokinase ANAPC4_WD40 PF12894.7 OAP61919.1 - 4e-07 30.2 0.0 0.85 10.0 0.0 4.6 4 2 2 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OAP61919.1 - 5.4e-06 27.0 0.1 0.071 14.0 0.0 4.9 4 0 0 4 4 4 1 WD domain, G-beta repeat PD40 PF07676.12 OAP61919.1 - 0.035 14.0 0.0 7.4 6.6 0.0 2.6 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 OAP61919.1 - 0.085 11.8 0.0 0.15 11.0 0.0 1.4 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein COG4 PF08318.12 OAP61921.1 - 1.8e-121 405.3 0.0 2.5e-121 404.8 0.0 1.2 1 0 0 1 1 1 1 COG4 transport protein HTH_57 PF18679.1 OAP61921.1 - 0.0058 16.9 0.3 1 9.7 0.0 2.7 2 0 0 2 2 2 1 ThcOx helix turn helix domain RTP1_C2 PF10304.9 OAP61921.1 - 0.098 12.4 0.1 0.31 10.8 0.1 2.0 1 0 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 2 CTD_bind PF04818.13 OAP61921.1 - 0.11 13.4 0.0 1.8 9.5 0.0 2.8 2 0 0 2 2 2 0 RNA polymerase II-binding domain. Nsp1_C PF05064.13 OAP61921.1 - 2.5 7.9 5.0 1.9 8.3 0.5 2.8 2 1 1 3 3 3 0 Nsp1-like C-terminal region WD40 PF00400.32 OAP61922.1 - 6.6e-44 147.0 26.6 1.3e-09 38.5 0.2 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAP61922.1 - 5.7e-09 36.2 0.4 0.12 12.7 0.0 4.3 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OAP61922.1 - 5.3e-05 22.1 7.6 0.12 11.0 0.1 4.3 1 1 2 4 4 4 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 OAP61922.1 - 0.0036 16.3 0.2 10 5.0 0.0 4.1 2 2 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 OAP61922.1 - 0.013 14.9 0.0 1.2 8.4 0.0 2.3 2 0 0 2 2 2 0 WD40-like domain PD40 PF07676.12 OAP61922.1 - 0.018 15.0 0.4 22 5.1 0.0 4.4 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 OAP61922.1 - 0.02 13.5 0.0 1.4 7.3 0.0 2.2 2 0 0 2 2 2 0 Cytochrome D1 heme domain Aldo_ket_red PF00248.21 OAP61923.1 - 5.6e-71 239.1 0.0 6.4e-71 238.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Sdh5 PF03937.16 OAP61924.1 - 3.3e-23 81.4 0.4 8.7e-23 80.1 0.2 1.7 2 0 0 2 2 2 1 Flavinator of succinate dehydrogenase MFS_1 PF07690.16 OAP61925.1 - 2e-38 132.2 41.9 3e-38 131.7 34.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 OAP61925.1 - 1.8e-09 36.6 2.6 3e-09 35.9 2.6 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) PAS PF00989.25 OAP61926.1 - 0.0042 17.1 0.0 0.093 12.7 0.0 2.3 2 0 0 2 2 2 1 PAS fold Zn_clus PF00172.18 OAP61926.1 - 0.0057 16.8 9.3 0.0057 16.8 9.3 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF874 PF05917.11 OAP61926.1 - 0.037 13.1 0.2 0.037 13.1 0.2 1.9 2 0 0 2 2 2 0 Helicobacter pylori protein of unknown function (DUF874) Flavokinase PF01687.17 OAP61927.1 - 2.5e-32 111.5 0.0 3.3e-32 111.1 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase Mito_fiss_reg PF05308.11 OAP61927.1 - 1.3 9.0 4.2 2 8.5 4.2 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 OAP61927.1 - 3 7.3 4.1 4.3 6.7 4.1 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal E1-E2_ATPase PF00122.20 OAP61928.1 - 4.2e-48 163.3 0.4 4.2e-48 163.3 0.4 2.7 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 OAP61928.1 - 1.4e-45 155.3 1.0 1.4e-45 155.3 1.0 2.2 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 OAP61928.1 - 7.2e-22 78.7 1.3 6.4e-21 75.6 1.3 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 OAP61928.1 - 2.5e-20 71.9 0.3 4.8e-20 71.0 0.3 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 OAP61928.1 - 1.5e-09 37.8 0.0 3.2e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 OAP61928.1 - 9.4e-07 28.8 0.9 2.2e-05 24.3 0.7 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DAGK_cat PF00781.24 OAP61928.1 - 0.067 12.8 0.2 0.57 9.8 0.0 2.3 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain ComFB PF10719.9 OAP61928.1 - 0.29 11.2 0.7 8.6 6.5 0.1 2.5 2 0 0 2 2 2 0 Late competence development protein ComFB Rad21_Rec8_N PF04825.13 OAP61929.1 - 8e-35 119.3 0.0 1.5e-34 118.5 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 OAP61929.1 - 2.7e-08 33.0 0.0 5.4e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein DUF3176 PF11374.8 OAP61930.1 - 1.3e-25 89.6 0.1 3.1e-25 88.4 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) Acyltransferase PF01553.21 OAP61931.1 - 4.2e-13 49.1 0.0 1.9e-12 47.0 0.0 1.9 1 1 0 1 1 1 1 Acyltransferase L31 PF09784.9 OAP61932.1 - 5.1e-46 155.3 1.0 5.7e-46 155.1 1.0 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 Val_tRNA-synt_C PF10458.9 OAP61932.1 - 0.11 12.8 0.7 3.8 7.9 0.7 2.4 1 1 1 2 2 2 0 Valyl tRNA synthetase tRNA binding arm Cas_APE2256 PF09651.10 OAP61932.1 - 0.12 12.2 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_APE2256) DUF1556 PF07590.11 OAP61933.1 - 0.67 10.3 5.0 0.95 9.8 2.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1556) SRAP PF02586.14 OAP61934.1 - 3.1e-80 268.8 0.3 5.9e-80 267.9 0.3 1.5 1 0 0 1 1 1 1 SOS response associated peptidase (SRAP) Roughex PF06020.11 OAP61934.1 - 0.0091 15.1 3.3 0.0091 15.1 3.3 2.0 2 0 0 2 2 2 1 Drosophila roughex protein DDHD PF02862.17 OAP61934.1 - 0.22 11.7 6.4 0.36 11.0 0.1 2.2 2 0 0 2 2 2 0 DDHD domain Neur_chan_memb PF02932.16 OAP61934.1 - 1.7 8.6 8.1 4.4 7.3 0.4 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region CPSF100_C PF13299.6 OAP61934.1 - 3.8 7.7 14.4 0.37 11.0 1.1 2.4 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal TPR_12 PF13424.6 OAP61935.1 - 0.00011 22.4 0.8 2 8.7 0.0 3.9 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 OAP61935.1 - 0.00055 19.9 2.7 2.6 8.5 0.2 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 OAP61935.1 - 0.01 15.9 0.9 2 8.7 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat RPN7 PF10602.9 OAP61935.1 - 0.02 14.6 0.0 2.3 7.9 0.0 2.7 3 0 0 3 3 3 0 26S proteasome subunit RPN7 TPR_19 PF14559.6 OAP61935.1 - 0.034 14.7 1.9 14 6.3 0.0 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat TAL_effector PF03377.13 OAP61935.1 - 0.092 13.1 0.0 0.89 9.9 0.0 2.5 2 0 0 2 2 2 0 TAL effector repeat TPR_14 PF13428.6 OAP61935.1 - 1.5 9.8 7.6 73 4.6 0.1 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF3433 PF11915.8 OAP61936.1 - 1.7e-33 114.9 24.0 9.8e-19 67.6 1.8 4.1 5 0 0 5 5 5 2 Protein of unknown function (DUF3433) LapA_dom PF06305.11 OAP61936.1 - 5.8 6.8 7.5 2.3 8.1 1.7 3.1 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Glyco_hydro_cc PF11790.8 OAP61937.1 - 8.7e-60 202.2 0.3 1.1e-59 201.9 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core RED_N PF07808.13 OAP61938.1 - 1.5e-11 44.3 7.0 1.5e-11 44.3 7.0 2.1 2 0 0 2 2 2 1 RED-like protein N-terminal region DUF1974 PF09317.11 OAP61938.1 - 0.35 10.4 2.2 0.56 9.7 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1974) Methyltransf_15 PF09445.10 OAP61939.1 - 1.3e-51 174.4 0.0 1.9e-51 173.9 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Met_10 PF02475.16 OAP61939.1 - 1.5e-06 28.1 0.0 1.9e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein UPF0020 PF01170.18 OAP61939.1 - 6.1e-06 26.1 0.6 0.00092 18.9 0.4 3.3 1 1 0 2 2 2 1 Putative RNA methylase family UPF0020 Methyltransf_25 PF13649.6 OAP61939.1 - 8e-05 23.3 0.0 0.00016 22.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 OAP61939.1 - 0.00038 20.4 0.0 0.00064 19.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OAP61939.1 - 0.002 17.7 0.0 0.0031 17.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Cons_hypoth95 PF03602.15 OAP61939.1 - 0.0041 16.8 0.0 0.011 15.4 0.0 1.6 1 1 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_11 PF08241.12 OAP61939.1 - 0.0052 17.4 0.0 0.011 16.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 OAP61939.1 - 0.016 14.6 0.1 0.023 14.1 0.1 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_5 PF01795.19 OAP61939.1 - 0.027 14.0 0.0 0.042 13.3 0.0 1.3 2 0 0 2 2 2 0 MraW methylase family N6_Mtase PF02384.16 OAP61939.1 - 0.053 12.8 0.0 0.079 12.2 0.0 1.2 1 0 0 1 1 1 0 N-6 DNA Methylase Methyltr_RsmB-F PF01189.17 OAP61939.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F DUF3591 PF12157.8 OAP61940.1 - 7.6e-174 578.5 5.0 1.5e-173 577.5 4.6 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3591) zf-CCHC PF00098.23 OAP61940.1 - 0.0088 16.1 0.7 0.0088 16.1 0.7 1.9 2 0 0 2 2 2 1 Zinc knuckle OrfB_Zn_ribbon PF07282.11 OAP61940.1 - 0.23 11.4 2.0 0.51 10.3 2.0 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-CCHC_6 PF15288.6 OAP61940.1 - 7.1 6.6 8.6 0.4 10.6 1.5 2.3 2 0 0 2 2 2 0 Zinc knuckle DAO PF01266.24 OAP61941.1 - 7.1e-34 117.9 0.5 1.5e-33 116.9 0.5 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 OAP61941.1 - 5.2e-08 33.0 0.2 0.014 15.4 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 OAP61941.1 - 1.7e-05 24.2 0.1 0.035 13.3 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 OAP61941.1 - 2.7e-05 23.2 0.0 0.0017 17.3 0.0 2.1 2 0 0 2 2 2 1 Tryptophan halogenase GIDA PF01134.22 OAP61941.1 - 3.3e-05 23.1 0.0 0.00014 21.1 0.0 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 OAP61941.1 - 0.00086 18.6 0.1 0.6 9.3 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAP61941.1 - 0.00097 19.3 0.0 0.0027 17.9 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GMC_oxred_N PF00732.19 OAP61941.1 - 0.0035 16.8 0.0 0.22 10.9 0.0 2.1 2 0 0 2 2 2 1 GMC oxidoreductase Lycopene_cycl PF05834.12 OAP61941.1 - 0.067 12.2 0.0 4.5 6.2 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein Thi4 PF01946.17 OAP61941.1 - 0.14 11.4 0.0 0.27 10.4 0.0 1.4 1 0 0 1 1 1 0 Thi4 family PALP PF00291.25 OAP61942.1 - 1.3e-08 34.6 0.0 2.7e-08 33.6 0.0 1.4 1 1 1 2 2 2 1 Pyridoxal-phosphate dependent enzyme Ring_hydroxyl_A PF00848.19 OAP61943.1 - 3.2e-25 89.4 1.7 1.8e-11 44.4 1.2 2.5 1 1 1 2 2 2 2 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.26 OAP61943.1 - 2.3e-14 53.1 0.0 4.7e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Fungal_trans PF04082.18 OAP61943.1 - 7.5e-05 21.9 0.0 0.00018 20.7 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain HrpB7 PF09486.10 OAP61943.1 - 0.11 12.9 0.6 4.3 7.7 1.0 2.2 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) GCV_T PF01571.21 OAP61944.1 - 2.2e-71 240.3 0.0 7.1e-71 238.6 0.0 1.7 2 0 0 2 2 2 1 Aminomethyltransferase folate-binding domain DAO PF01266.24 OAP61944.1 - 7e-48 164.0 1.3 9.1e-48 163.6 0.2 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase GCV_T_C PF08669.11 OAP61944.1 - 1.7e-23 82.3 0.1 3.9e-23 81.2 0.1 1.7 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain FAO_M PF16350.5 OAP61944.1 - 2.1e-19 69.6 0.0 4.3e-19 68.6 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase central domain Pyr_redox_2 PF07992.14 OAP61944.1 - 1.9e-05 24.0 0.1 0.087 12.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAP61944.1 - 4.5e-05 23.9 0.1 0.21 12.2 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 OAP61944.1 - 0.0021 18.3 0.3 0.011 16.0 0.1 2.2 3 0 0 3 3 3 1 TrkA-N domain NAD_binding_9 PF13454.6 OAP61944.1 - 0.0022 18.0 0.3 0.25 11.3 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding ThiF PF00899.21 OAP61944.1 - 0.0071 15.7 0.1 0.015 14.6 0.1 1.4 1 0 0 1 1 1 1 ThiF family SoxG PF04268.12 OAP61944.1 - 0.0086 16.2 0.0 0.19 11.9 0.0 2.5 2 0 0 2 2 2 1 Sarcosine oxidase, gamma subunit family FAD_binding_3 PF01494.19 OAP61944.1 - 0.023 14.0 0.1 3.5 6.8 0.1 2.2 2 0 0 2 2 2 0 FAD binding domain NAD_binding_8 PF13450.6 OAP61944.1 - 0.038 14.2 0.0 0.13 12.5 0.0 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain F420_oxidored PF03807.17 OAP61944.1 - 0.069 13.7 0.1 0.38 11.4 0.0 2.2 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 OAP61944.1 - 0.11 12.5 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FKBP_C PF00254.28 OAP61945.1 - 1.5e-28 99.0 0.1 7.2e-28 96.8 0.0 2.2 3 0 0 3 3 3 1 FKBP-type peptidyl-prolyl cis-trans isomerase NPL PF17800.1 OAP61945.1 - 4.8e-25 88.1 2.9 4.8e-25 88.1 2.9 2.8 2 2 0 2 2 2 1 Nucleoplasmin-like domain IMS PF00817.20 OAP61946.1 - 2.6e-43 147.6 0.0 5.1e-43 146.6 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family REV1_C PF16727.5 OAP61946.1 - 3.6e-22 78.5 0.7 7.6e-22 77.5 0.7 1.6 1 0 0 1 1 1 1 DNA repair protein REV1 C-terminal domain IMS_C PF11799.8 OAP61946.1 - 4.2e-14 53.2 0.0 4.7e-13 49.9 0.0 2.5 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain UBM PF14377.6 OAP61946.1 - 4.3e-14 51.4 19.4 4.8e-06 25.8 1.0 4.2 4 0 0 4 4 4 3 Ubiquitin binding region BRCT_2 PF16589.5 OAP61946.1 - 8.9e-10 38.9 0.0 2.3e-09 37.5 0.0 1.8 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 OAP61946.1 - 6.8e-06 26.4 0.0 4.4e-05 23.8 0.0 2.4 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain mCpol PF18182.1 OAP61946.1 - 0.00044 20.6 0.0 0.0012 19.2 0.0 1.7 1 0 0 1 1 1 1 minimal CRISPR polymerase domain PTCB-BRCT PF12738.7 OAP61946.1 - 0.0011 18.8 0.0 0.0027 17.6 0.0 1.7 1 0 0 1 1 1 1 twin BRCT domain IMS_HHH PF11798.8 OAP61946.1 - 0.0022 18.2 0.3 0.019 15.2 0.1 2.7 2 0 0 2 2 2 1 IMS family HHH motif DUF1805 PF08827.11 OAP61946.1 - 0.043 14.2 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) DUF4364 PF14277.6 OAP61946.1 - 0.13 12.0 0.7 0.28 10.9 0.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4364) Pkinase PF00069.25 OAP61947.1 - 9.4e-34 117.0 2.4 1.4e-26 93.4 0.1 3.8 3 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAP61947.1 - 8.2e-14 51.5 0.0 1.9e-12 47.0 0.0 2.6 3 0 0 3 3 3 1 Protein tyrosine kinase APH PF01636.23 OAP61947.1 - 0.0089 16.0 0.3 0.0089 16.0 0.3 2.4 2 1 1 3 3 3 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 OAP61947.1 - 0.082 11.9 0.1 0.13 11.2 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Oxidored_FMN PF00724.20 OAP61948.1 - 8.6e-91 304.7 0.0 1e-90 304.5 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AP_endonuc_2 PF01261.24 OAP61948.1 - 0.023 14.1 0.1 9.1 5.7 0.0 3.1 2 2 1 3 3 3 0 Xylose isomerase-like TIM barrel MFS_1 PF07690.16 OAP61951.1 - 9.3e-29 100.4 32.1 1.2e-28 100.1 32.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Trp_oprn_chp PF09534.10 OAP61951.1 - 0.018 14.8 1.5 0.03 14.1 0.4 1.9 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Arf PF00025.21 OAP61952.1 - 1.5e-42 145.0 0.0 1.8e-42 144.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 OAP61952.1 - 1.2e-18 67.3 0.0 1.3e-18 67.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAP61952.1 - 4.8e-15 55.8 0.0 7.3e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 OAP61952.1 - 8.4e-10 38.7 0.0 1.2e-09 38.2 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OAP61952.1 - 3.8e-08 33.0 0.0 4.4e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 OAP61952.1 - 1.8e-07 30.8 0.0 2e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 OAP61952.1 - 0.00012 21.4 0.2 0.0005 19.3 0.0 2.0 2 1 1 3 3 3 1 G-protein alpha subunit FeoB_N PF02421.18 OAP61952.1 - 0.00017 21.1 1.0 0.00075 19.1 1.0 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 OAP61952.1 - 0.00023 21.3 0.0 0.075 13.1 0.1 2.2 1 1 1 2 2 2 2 Dynamin family GTP_EFTU PF00009.27 OAP61952.1 - 0.0018 17.9 0.0 0.023 14.2 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 OAP61952.1 - 0.028 14.9 0.0 0.033 14.7 0.0 1.4 1 1 0 1 1 1 0 ABC transporter PduV-EutP PF10662.9 OAP61952.1 - 0.1 12.4 0.0 1.3 8.7 0.0 2.3 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1_Xtn PF16897.5 OAP61952.1 - 0.12 12.4 0.0 0.26 11.3 0.0 1.6 2 0 0 2 2 2 0 C-terminal region of MMR_HSR1 domain RCR PF12273.8 OAP61953.1 - 1.4e-21 77.4 9.6 1.6e-21 77.1 9.6 1.1 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red SARAF PF06682.12 OAP61953.1 - 0.0069 16.1 0.9 0.0097 15.6 0.9 1.4 1 1 1 2 2 2 1 SOCE-associated regulatory factor of calcium homoeostasis LapA_dom PF06305.11 OAP61953.1 - 0.79 9.6 2.9 1.1 9.1 2.9 1.2 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain DUF4381 PF14316.6 OAP61953.1 - 9 6.5 9.6 0.51 10.6 4.3 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Conotoxin PF02950.17 OAP61955.1 - 0.047 14.7 2.2 0.78 10.8 0.0 2.5 2 0 0 2 2 2 0 Conotoxin Chromate_transp PF02417.15 OAP61956.1 - 0.21 11.7 7.4 1.1 9.4 2.2 2.6 2 0 0 2 2 2 0 Chromate transporter Proteasome PF00227.26 OAP61957.1 - 4.1e-47 160.1 0.2 5e-47 159.9 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Cupin_5 PF06172.11 OAP61958.1 - 6e-50 169.1 0.0 7.6e-50 168.7 0.0 1.1 1 0 0 1 1 1 1 Cupin superfamily (DUF985) EF_assoc_2 PF08356.12 OAP61959.1 - 7.2e-35 118.8 0.0 1.3e-34 118.0 0.0 1.5 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.12 OAP61959.1 - 2.2e-29 100.8 1.7 2.9e-29 100.5 0.8 1.7 2 0 0 2 2 1 1 EF hand associated Ras PF00071.22 OAP61959.1 - 1.6e-25 89.6 0.0 5.5e-15 55.3 0.0 2.2 2 0 0 2 2 2 2 Ras family Roc PF08477.13 OAP61959.1 - 1.8e-13 50.7 0.0 1.1e-08 35.3 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 OAP61959.1 - 1.7e-08 34.5 0.0 0.00012 22.2 0.0 2.9 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.6 OAP61959.1 - 0.00043 20.6 0.0 1.1 9.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 OAP61959.1 - 0.00065 19.4 0.1 0.29 10.9 0.0 2.7 3 0 0 3 3 2 1 P-loop containing region of AAA domain Dynamin_N PF00350.23 OAP61959.1 - 0.00072 19.7 0.0 0.28 11.2 0.0 2.9 3 0 0 3 3 2 1 Dynamin family AAA_16 PF13191.6 OAP61959.1 - 0.0015 18.9 0.1 2.5 8.4 0.0 2.8 3 0 0 3 3 3 2 AAA ATPase domain EF-hand_1 PF00036.32 OAP61959.1 - 0.0037 16.7 2.2 0.26 10.9 0.4 2.6 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 OAP61959.1 - 0.004 17.6 2.4 0.32 11.5 0.9 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_10 PF14788.6 OAP61959.1 - 0.0077 16.1 2.2 0.2 11.5 0.2 2.7 3 0 0 3 3 2 1 EF hand RNA_helicase PF00910.22 OAP61959.1 - 0.013 15.9 0.0 0.28 11.6 0.0 2.5 2 0 0 2 2 2 0 RNA helicase GTP_EFTU PF00009.27 OAP61959.1 - 0.015 14.8 0.0 8.6 5.8 0.0 3.1 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OAP61959.1 - 0.031 14.2 0.0 1 9.3 0.0 2.7 2 0 0 2 2 2 0 RsgA GTPase EF-hand_6 PF13405.6 OAP61959.1 - 0.038 13.9 2.7 0.98 9.5 0.3 2.7 2 0 0 2 2 2 0 EF-hand domain AAA_18 PF13238.6 OAP61959.1 - 0.07 13.7 0.1 1.7 9.2 0.0 2.9 3 1 0 3 3 3 0 AAA domain AAA_28 PF13521.6 OAP61959.1 - 0.1 12.9 0.0 5.9 7.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 OAP61959.1 - 0.19 12.3 0.0 1.8 9.1 0.0 2.2 2 0 0 2 2 2 0 ABC transporter AAA_25 PF13481.6 OAP61959.1 - 0.19 11.3 0.1 17 4.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain Septin PF00735.18 OAP61959.1 - 0.2 10.9 0.0 0.49 9.6 0.0 1.6 1 0 0 1 1 1 0 Septin EF-hand_8 PF13833.6 OAP61959.1 - 0.33 10.8 2.8 7.5 6.5 0.1 2.8 2 0 0 2 2 2 0 EF-hand domain pair Ysc84 PF04366.12 OAP61960.1 - 1.7e-41 141.0 0.3 3.1e-41 140.1 0.3 1.4 1 0 0 1 1 1 1 Las17-binding protein actin regulator SH3_1 PF00018.28 OAP61960.1 - 1.5e-14 53.3 0.3 4.7e-14 51.7 0.1 1.9 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 OAP61960.1 - 1.8e-13 50.0 0.1 6.4e-13 48.2 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.6 OAP61960.1 - 1.1e-10 41.2 0.0 2.1e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain MFS_1 PF07690.16 OAP61961.1 - 5.6e-18 65.0 32.4 5.6e-18 65.0 32.4 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily 7TMR-DISM_7TM PF07695.11 OAP61961.1 - 0.003 17.5 10.4 0.003 17.5 10.4 3.5 2 1 1 3 3 3 1 7TM diverse intracellular signalling Sugar_tr PF00083.24 OAP61961.1 - 0.026 13.4 28.3 2.6 6.8 28.3 2.8 1 1 0 1 1 1 0 Sugar (and other) transporter HlyIII PF03006.20 OAP61961.1 - 0.042 13.6 9.1 0.043 13.5 0.2 2.4 2 0 0 2 2 2 0 Haemolysin-III related DDHD PF02862.17 OAP61962.1 - 9.9e-60 202.5 0.7 1.1e-58 199.0 0.1 2.4 2 0 0 2 2 2 1 DDHD domain DUF676 PF05057.14 OAP61962.1 - 0.07 12.6 0.2 0.82 9.1 0.0 2.5 3 0 0 3 3 3 0 Putative serine esterase (DUF676) AAR2 PF05282.11 OAP61962.1 - 9.9 5.5 7.9 0.15 11.5 0.4 1.7 2 0 0 2 2 2 0 AAR2 protein CH PF00307.31 OAP61963.1 - 2e-71 237.1 0.0 2.9e-18 66.0 0.0 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.6 OAP61963.1 - 3.1e-08 33.9 1.7 2.3e-07 31.1 1.0 2.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 OAP61963.1 - 1.3e-05 24.3 1.0 0.42 10.3 0.1 3.5 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 OAP61963.1 - 0.00011 21.8 0.9 0.013 15.4 0.0 3.2 3 0 0 3 3 3 1 EF-hand domain CAMSAP_CH PF11971.8 OAP61963.1 - 0.0046 16.8 0.0 0.19 11.5 0.0 3.3 4 0 0 4 4 4 1 CAMSAP CH domain DLH PF01738.18 OAP61964.1 - 2.6e-30 105.6 0.0 3.1e-30 105.4 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family MFS_1 PF07690.16 OAP61965.1 - 2.5e-30 105.6 21.8 3.7e-30 105.1 21.8 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily HET PF06985.11 OAP61966.1 - 2.8e-35 121.8 0.0 2.9e-29 102.3 0.0 2.3 2 0 0 2 2 2 2 Heterokaryon incompatibility protein (HET) Ppx-GppA PF02541.16 OAP61967.1 - 6.9e-42 143.8 0.0 2.5e-31 109.2 0.0 2.1 2 0 0 2 2 2 2 Ppx/GppA phosphatase family GDA1_CD39 PF01150.17 OAP61967.1 - 0.027 13.1 0.1 0.057 12.1 0.1 1.5 1 0 0 1 1 1 0 GDA1/CD39 (nucleoside phosphatase) family SWI-SNF_Ssr4 PF08549.10 OAP61968.1 - 1.2e-182 609.4 28.7 1.8e-181 605.4 28.7 2.0 1 1 0 1 1 1 1 Fungal domain of unknown function (DUF1750) Sod_Cu PF00080.20 OAP61968.1 - 0.038 14.1 0.6 0.078 13.1 0.6 1.4 1 0 0 1 1 1 0 Copper/zinc superoxide dismutase (SODC) Uds1 PF15456.6 OAP61968.1 - 0.18 12.0 4.3 0.4 10.8 4.3 1.5 1 0 0 1 1 1 0 Up-regulated During Septation SLD5_C PF16922.5 OAP61969.1 - 1.2e-11 44.6 0.7 1.9e-11 44.0 0.7 1.3 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus Sld5 PF05916.11 OAP61969.1 - 1.4e-05 25.5 0.0 2.7e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 GINS complex protein UBM PF14377.6 OAP61969.1 - 0.07 12.6 0.0 0.15 11.5 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin binding region Chlor_dismutase PF06778.12 OAP61969.1 - 0.079 12.5 0.1 0.1 12.1 0.1 1.2 1 0 0 1 1 1 0 Chlorite dismutase Cullin PF00888.22 OAP61970.1 - 5.7e-192 639.6 11.8 7.2e-192 639.3 11.8 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 OAP61970.1 - 1.3e-26 92.4 0.1 1.3e-26 92.4 0.1 3.0 4 0 0 4 4 4 1 Cullin protein neddylation domain HTH_IclR PF09339.10 OAP61970.1 - 0.011 15.6 0.0 0.04 13.7 0.0 2.0 2 0 0 2 2 2 0 IclR helix-turn-helix domain Gam PF06064.11 OAP61970.1 - 0.021 15.0 1.2 0.066 13.5 0.1 2.4 2 1 1 3 3 3 0 Host-nuclease inhibitor protein Gam Rrf2 PF02082.20 OAP61970.1 - 0.032 14.6 0.3 0.17 12.2 0.0 2.3 2 0 0 2 2 2 0 Transcriptional regulator zf-DNL PF05180.12 OAP61971.1 - 3e-26 91.1 0.6 4.8e-26 90.5 0.6 1.3 1 0 0 1 1 1 1 DNL zinc finger zinc_ribbon_4 PF13717.6 OAP61971.1 - 0.075 13.0 0.1 0.075 13.0 0.1 1.7 2 0 0 2 2 2 0 zinc-ribbon domain Alpha-amylase PF00128.24 OAP61972.1 - 1.8e-115 386.1 0.2 2.6e-115 385.6 0.2 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF3459 PF11941.8 OAP61972.1 - 1.1e-05 25.6 0.1 8.8e-05 22.8 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3459) hDGE_amylase PF14701.6 OAP61972.1 - 0.066 12.3 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain DUF3533 PF12051.8 OAP61973.1 - 4.9e-79 266.0 2.9 5.6e-79 265.8 2.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) Alpha-L-AF_C PF06964.12 OAP61974.1 - 9.3e-28 97.4 0.3 1.9e-27 96.4 0.3 1.5 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain F-box PF00646.33 OAP61975.1 - 0.0013 18.5 0.2 0.0046 16.8 0.2 2.0 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 OAP61975.1 - 0.0032 17.3 0.1 0.0085 16.0 0.1 1.8 1 0 0 1 1 1 1 F-box-like Sugar_tr PF00083.24 OAP61976.1 - 2.7e-76 257.3 23.2 3.1e-76 257.1 23.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP61976.1 - 2.3e-16 59.7 37.9 5e-10 38.8 18.4 2.8 1 1 2 3 3 3 2 Major Facilitator Superfamily ABC2_membrane_3 PF12698.7 OAP61976.1 - 0.003 16.7 0.9 0.003 16.7 0.9 2.3 2 2 0 2 2 2 1 ABC-2 family transporter protein MFS_1_like PF12832.7 OAP61976.1 - 3 6.6 16.1 0.0072 15.2 2.5 2.4 2 1 1 3 3 3 0 MFS_1 like family DUF4131 PF13567.6 OAP61976.1 - 3.6 7.2 8.6 0.36 10.5 2.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Questin_oxidase PF14027.6 OAP61979.1 - 1.3e-84 284.7 1.7 1.5e-84 284.5 1.7 1.0 1 0 0 1 1 1 1 Questin oxidase-like Ldh_2 PF02615.14 OAP61980.1 - 5.3e-127 423.6 0.1 5.9e-127 423.4 0.1 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase PHY PF00360.20 OAP61981.1 - 2.2e-28 98.8 0.0 2.5e-27 95.4 0.0 2.2 2 0 0 2 2 2 1 Phytochrome region HATPase_c PF02518.26 OAP61981.1 - 1.2e-17 64.4 0.1 2.8e-17 63.3 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 OAP61981.1 - 2.4e-13 50.2 0.0 7.4e-13 48.6 0.0 1.9 1 1 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 OAP61981.1 - 6.9e-13 48.4 0.4 2.1e-12 46.9 0.4 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF PF01590.26 OAP61981.1 - 9.6e-13 48.9 0.0 5.5e-12 46.5 0.0 2.2 2 0 0 2 2 2 1 GAF domain PAS_2 PF08446.11 OAP61981.1 - 1.7e-09 38.3 0.0 5.8e-09 36.6 0.0 2.0 1 0 0 1 1 1 1 PAS fold Fungal_trans_2 PF11951.8 OAP61982.1 - 0.07 11.9 0.2 0.82 8.4 0.0 2.2 2 0 0 2 2 2 0 Fungal specific transcription factor domain zf-RRN7 PF11781.8 OAP61983.1 - 0.14 11.8 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 MARVEL PF01284.23 OAP61983.1 - 0.16 12.0 16.9 0.36 10.9 17.0 1.5 1 1 0 1 1 1 0 Membrane-associating domain DUF2070 PF09843.9 OAP61983.1 - 1.7 6.9 9.4 2 6.6 9.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) UCH_1 PF13423.6 OAP61984.1 - 6e-95 318.5 0.1 8.2e-95 318.1 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.24 OAP61984.1 - 1.7e-12 48.2 0.0 3.8e-12 47.0 0.0 1.6 1 0 0 1 1 1 1 Exonuclease UCH PF00443.29 OAP61984.1 - 0.00099 18.7 0.0 0.0021 17.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ANAPC4_WD40 PF12894.7 OAP61984.1 - 0.17 12.2 0.0 9.1 6.7 0.0 2.8 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Serglycin PF04360.12 OAP61984.1 - 0.17 11.8 3.6 0.5 10.3 3.6 1.7 1 0 0 1 1 1 0 Serglycin zf-RING_2 PF13639.6 OAP61985.1 - 8.1e-09 35.7 2.1 1.2e-08 35.2 2.1 1.2 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 OAP61985.1 - 3.1e-05 24.2 3.3 0.00023 21.4 3.3 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 OAP61985.1 - 0.00017 21.6 5.4 0.00028 20.8 5.4 1.3 1 0 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 OAP61985.1 - 0.0017 18.4 0.1 0.0025 17.9 0.1 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 OAP61985.1 - 0.0099 15.6 3.7 0.018 14.8 3.7 1.4 1 0 0 1 1 1 1 RING-like zinc finger zinc_ribbon_9 PF14369.6 OAP61985.1 - 0.023 14.9 0.1 0.057 13.7 0.1 1.6 1 0 0 1 1 1 0 zinc-ribbon zf-C3HC4_2 PF13923.6 OAP61985.1 - 0.035 14.0 3.0 0.097 12.5 3.2 1.6 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAP61985.1 - 0.17 11.8 1.2 0.3 11.0 1.2 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) ADH_N_2 PF16884.5 OAP61986.1 - 7.7e-25 86.9 0.0 1.5e-24 86.0 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 OAP61986.1 - 2.3e-22 79.4 0.1 5.4e-22 78.2 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAP61986.1 - 1.5e-07 32.5 0.0 3.9e-07 31.2 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase DapB_N PF01113.20 OAP61986.1 - 0.11 12.6 0.4 0.21 11.7 0.3 1.6 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Sulfatase PF00884.23 OAP61987.1 - 2.2e-76 257.2 0.0 2.7e-76 256.9 0.0 1.1 1 0 0 1 1 1 1 Sulfatase DUF4994 PF16385.5 OAP61987.1 - 7.9e-05 22.5 0.0 0.00016 21.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function Sulfatase_C PF14707.6 OAP61987.1 - 0.0025 18.6 0.0 0.075 13.8 0.0 2.4 1 1 0 1 1 1 1 C-terminal region of aryl-sulfatase DUF4976 PF16347.5 OAP61987.1 - 0.0066 16.7 0.4 0.038 14.2 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4976) Sugar_tr PF00083.24 OAP61988.1 - 3.7e-110 368.9 27.0 4.5e-110 368.6 27.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP61988.1 - 2.1e-18 66.4 30.4 2.1e-18 66.4 30.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Pox_MCEL PF03291.16 OAP61989.1 - 2.5e-67 227.4 0.0 3.4e-64 217.1 0.0 2.6 1 1 0 1 1 1 1 mRNA capping enzyme Methyltransf_25 PF13649.6 OAP61989.1 - 1.5e-10 41.7 0.0 3.7e-05 24.4 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 OAP61989.1 - 4.4e-09 37.0 0.0 2e-08 34.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAP61989.1 - 5.6e-08 33.3 0.1 1.3e-06 29.0 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAP61989.1 - 9.2e-07 28.8 0.0 0.00012 21.9 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAP61989.1 - 5.5e-06 26.3 0.0 1e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 OAP61989.1 - 0.016 14.4 0.0 0.027 13.7 0.0 1.3 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Raftlin PF15250.6 OAP61989.1 - 0.79 8.4 2.4 1.2 7.8 0.0 2.0 2 0 0 2 2 2 0 Raftlin C1_1 PF00130.22 OAP61990.1 - 0.00083 19.2 2.1 0.0017 18.2 2.1 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_2 PF13639.6 OAP61990.1 - 0.0012 19.2 5.2 0.0033 17.7 5.2 1.8 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.8 OAP61990.1 - 0.11 12.7 4.3 0.25 11.5 4.3 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain PHD PF00628.29 OAP61990.1 - 2.6 8.0 8.7 0.51 10.3 4.4 2.0 2 0 0 2 2 2 0 PHD-finger Hen1_L PF12623.7 OAP61991.1 - 3 6.8 8.4 64 2.5 0.1 5.0 2 2 5 7 7 7 0 RNA repair, ligase-Pnkp-associating, region of Hen1 GRASP55_65 PF04495.14 OAP61992.1 - 9.7e-41 139.3 0.0 1.3e-39 135.7 0.0 2.0 2 0 0 2 2 2 1 GRASP55/65 PDZ-like domain HD PF01966.22 OAP61993.1 - 0.00014 22.0 0.3 0.0009 19.5 0.2 2.3 2 1 0 2 2 2 1 HD domain Nore1-SARAH PF16517.5 OAP61993.1 - 0.06 13.3 0.5 0.16 11.9 0.5 1.7 1 0 0 1 1 1 0 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain HBB PF06777.11 OAP61993.1 - 0.084 12.5 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Helical and beta-bridge domain Methyltransf_2 PF00891.18 OAP61994.1 - 1.8e-27 96.0 0.0 3e-27 95.3 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 OAP61994.1 - 0.0027 18.4 0.0 0.0085 16.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAP61994.1 - 0.0055 17.4 0.0 0.018 15.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain DUF1413 PF07205.11 OAP61994.1 - 0.025 14.6 0.0 0.065 13.2 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1413) bZIP_1 PF00170.21 OAP61995.1 - 1.8e-07 31.2 12.3 3e-07 30.4 12.3 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 OAP61995.1 - 0.00028 21.4 6.9 0.00053 20.4 6.9 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_2 PF07716.15 OAP61995.1 - 0.00063 19.8 12.8 0.001 19.1 12.8 1.3 1 0 0 1 1 1 1 Basic region leucine zipper GvpL_GvpF PF06386.11 OAP61995.1 - 0.023 14.7 0.9 0.031 14.2 0.9 1.2 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF DUF4778 PF16008.5 OAP61995.1 - 0.031 14.3 1.9 0.039 14.0 1.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) DNA_methylase PF00145.17 OAP61995.1 - 0.05 12.9 0.3 0.058 12.7 0.3 1.1 1 0 0 1 1 1 0 C-5 cytosine-specific DNA methylase CDC45 PF02724.14 OAP61995.1 - 0.066 11.5 4.3 0.078 11.3 4.3 1.1 1 0 0 1 1 1 0 CDC45-like protein OrfB_IS605 PF01385.19 OAP61995.1 - 0.097 12.9 2.8 0.16 12.2 2.8 1.4 1 0 0 1 1 1 0 Probable transposase p450 PF00067.22 OAP61996.1 - 6.7e-76 255.9 0.0 8.6e-76 255.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4708 PF15813.5 OAP61996.1 - 0.16 11.1 0.0 0.26 10.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4708) AP_endonuc_2 PF01261.24 OAP61997.1 - 1.2e-29 103.2 0.0 1.8e-29 102.7 0.0 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel YL1 PF05764.13 OAP61998.1 - 3.4e-50 171.4 38.4 3.4e-50 171.4 38.4 3.1 3 1 0 3 3 3 1 YL1 nuclear protein YL1_C PF08265.11 OAP61998.1 - 1.5e-07 31.0 0.0 2.6e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Ecl1 PF12855.7 OAP61999.1 - 5.3e-43 148.2 28.0 1.2e-42 147.0 28.0 1.6 1 1 0 1 1 1 1 ECL1/2/3 zinc binding proteins zf-MYND PF01753.18 OAP61999.1 - 0.0011 19.0 4.0 0.0023 18.0 4.0 1.4 1 0 0 1 1 1 1 MYND finger zf-FLZ PF04570.14 OAP61999.1 - 0.13 11.7 6.2 0.8 9.2 6.2 2.0 1 1 0 1 1 1 0 zinc-finger of the FCS-type, C2-C2 DUF2256 PF10013.9 OAP61999.1 - 1.5 9.0 5.5 8.8 6.5 5.5 2.0 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2256) PhoLip_ATPase_C PF16212.5 OAP62000.1 - 7.7e-79 265.0 24.6 7.7e-79 265.0 24.6 2.1 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 OAP62000.1 - 2.2e-25 88.1 5.6 7.8e-25 86.4 5.6 2.0 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 OAP62000.1 - 2.5e-11 44.3 1.8 5e-07 30.2 0.3 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 OAP62000.1 - 3.1e-10 40.0 0.0 1.8e-09 37.5 0.0 2.2 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 OAP62000.1 - 1.8e-08 34.1 0.0 4.6e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 OAP62000.1 - 0.0031 17.3 0.3 0.027 14.2 0.1 2.2 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase RNase_PH PF01138.21 OAP62001.1 - 2.7e-23 82.9 0.0 4.4e-23 82.2 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 OAP62001.1 - 1.1e-09 38.2 0.0 1.9e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 DUF348 PF03990.14 OAP62001.1 - 0.0037 17.0 0.3 0.024 14.4 0.1 2.3 2 0 0 2 2 2 1 G5-linked-Ubiquitin-like domain RT_RNaseH PF17917.1 OAP62001.1 - 0.0081 16.4 0.0 4.2 7.7 0.0 2.4 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 OAP62001.1 - 0.065 13.3 0.0 3.5 7.7 0.0 2.4 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase Cwf_Cwc_15 PF04889.12 OAP62002.1 - 4.6e-64 216.5 25.7 8.4e-64 215.7 21.1 2.3 2 0 0 2 2 2 1 Cwf15/Cwc15 cell cycle control protein ThrE PF06738.12 OAP62002.1 - 1.1e-60 205.0 19.0 4.7e-57 193.1 3.5 2.3 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 OAP62002.1 - 5.2e-10 39.6 29.7 6.5e-10 39.2 9.4 2.6 3 0 0 3 3 3 2 Threonine/Serine exporter, ThrE GDE_N PF12439.8 OAP62002.1 - 0.0086 15.5 0.0 0.02 14.3 0.0 1.6 1 0 0 1 1 1 1 Glycogen debranching enzyme N terminal PA26 PF04636.13 OAP62002.1 - 8.8 5.1 6.0 17 4.2 6.0 1.4 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DHFR_1 PF00186.19 OAP62004.1 - 3.1e-19 69.2 0.0 1.3e-08 34.7 0.0 4.4 4 1 0 4 4 4 4 Dihydrofolate reductase Med22 PF06179.12 OAP62005.1 - 5.1e-10 39.5 0.1 8.2e-10 38.8 0.1 1.5 1 1 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex DBR1 PF05011.13 OAP62005.1 - 0.1 13.0 0.0 0.12 12.8 0.0 1.3 1 0 0 1 1 1 0 Lariat debranching enzyme, C-terminal domain ATG13 PF10033.9 OAP62007.1 - 2.5e-69 233.6 0.0 5.7e-69 232.5 0.0 1.6 2 0 0 2 2 2 1 Autophagy-related protein 13 RCC1 PF00415.18 OAP62008.1 - 6.1e-21 74.8 0.2 2.3e-05 24.9 0.0 5.9 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 OAP62008.1 - 5.7e-16 58.7 0.2 3e-09 37.1 0.0 2.5 2 0 0 2 2 2 2 BTB/POZ domain Ank_4 PF13637.6 OAP62008.1 - 1.5e-09 38.2 0.1 5.8e-09 36.3 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) RCC1_2 PF13540.6 OAP62008.1 - 1.1e-08 34.6 10.8 6.6e-08 32.2 1.0 4.3 5 0 0 5 5 5 1 Regulator of chromosome condensation (RCC1) repeat Ank_2 PF12796.7 OAP62008.1 - 4.1e-08 33.7 0.0 1.5e-07 31.9 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OAP62008.1 - 7.8e-06 25.9 0.3 0.37 11.5 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 OAP62008.1 - 0.0086 16.5 0.1 0.32 11.5 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 OAP62008.1 - 0.0099 16.2 0.1 0.29 11.5 0.0 3.0 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Asp PF00026.23 OAP62009.1 - 1.2e-64 218.8 4.2 1.6e-64 218.4 4.2 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OAP62009.1 - 6.4e-14 52.6 0.3 1e-07 32.4 0.1 2.7 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 OAP62009.1 - 0.14 11.9 0.2 0.96 9.2 0.2 2.2 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal DUF2834 PF11196.8 OAP62010.1 - 0.38 11.1 9.3 1.7 9.0 0.8 3.9 3 1 1 4 4 4 0 Protein of unknown function (DUF2834) BUD22 PF09073.10 OAP62011.1 - 1.2e-85 288.5 11.4 1.8e-85 287.9 11.4 1.3 1 0 0 1 1 1 1 BUD22 ParA PF10609.9 OAP62012.1 - 7.5e-88 294.1 0.2 1.1e-87 293.6 0.2 1.2 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase Abhydrolase_3 PF07859.13 OAP62012.1 - 3.8e-41 141.3 0.1 3.7e-30 105.4 0.0 3.3 3 0 0 3 3 3 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 OAP62012.1 - 3.7e-14 52.4 0.0 9.6e-14 51.0 0.0 1.6 2 0 0 2 2 2 1 Steryl acetyl hydrolase CbiA PF01656.23 OAP62012.1 - 1.3e-10 41.4 0.0 3.4e-10 40.0 0.0 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 OAP62012.1 - 8.4e-06 25.8 0.1 2e-05 24.6 0.1 1.7 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.15 OAP62012.1 - 0.00076 18.8 1.2 0.0064 15.7 0.2 2.4 2 1 1 3 3 3 1 Anion-transporting ATPase MipZ PF09140.11 OAP62012.1 - 0.0016 17.7 0.1 0.003 16.9 0.1 1.4 1 0 0 1 1 1 1 ATPase MipZ AAA_25 PF13481.6 OAP62012.1 - 0.039 13.5 0.0 0.1 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain COesterase PF00135.28 OAP62012.1 - 0.041 12.8 0.3 0.34 9.7 0.3 2.0 1 1 0 1 1 1 0 Carboxylesterase family CLP1_P PF16575.5 OAP62012.1 - 0.054 13.3 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Asp PF00026.23 OAP62013.1 - 1.4e-38 133.1 0.0 6e-38 131.0 0.0 1.8 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 OAP62013.1 - 0.00034 21.2 1.3 0.021 15.4 0.2 3.4 2 1 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 OAP62013.1 - 0.00075 20.0 0.1 0.082 13.5 0.0 3.3 3 0 0 3 3 3 1 gag-polyprotein putative aspartyl protease Zn_clus PF00172.18 OAP62014.1 - 3.2e-07 30.4 7.8 5.1e-07 29.7 7.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_4 PF01565.23 OAP62015.1 - 7.3e-25 87.3 0.0 1.3e-24 86.5 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.19 OAP62015.1 - 3.8e-11 43.1 0.0 6.3e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain LisH PF08513.11 OAP62015.1 - 0.15 12.1 1.6 0.41 10.7 0.2 2.4 3 0 0 3 3 3 0 LisH Sugar_tr PF00083.24 OAP62016.1 - 1.1e-75 255.3 33.0 1.3e-75 255.1 33.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP62016.1 - 3.5e-29 101.8 44.9 2.6e-24 85.8 21.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily adh_short_C2 PF13561.6 OAP62017.1 - 4.7e-52 176.9 6.5 1.9e-38 132.3 4.8 3.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP62017.1 - 2.8e-41 141.2 1.4 4.4e-41 140.5 1.4 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAP62017.1 - 2.2e-07 31.0 0.2 4.3e-07 30.0 0.2 1.5 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OAP62017.1 - 0.0093 15.1 0.0 0.014 14.6 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein PALP PF00291.25 OAP62017.1 - 0.03 13.7 0.4 0.052 13.0 0.4 1.3 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme VCBS PF13517.6 OAP62017.1 - 0.14 12.8 0.2 0.7 10.5 0.1 2.1 2 0 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella ThiF PF00899.21 OAP62017.1 - 5.9 6.2 6.1 1.2 8.5 1.7 1.9 2 1 1 3 3 3 0 ThiF family FMO-like PF00743.19 OAP62018.1 - 1.2e-13 50.4 0.1 8e-13 47.7 0.1 2.1 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OAP62018.1 - 1.8e-12 47.3 0.0 4.1e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 OAP62018.1 - 2.6e-07 30.2 0.0 0.0026 17.1 0.0 3.4 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAP62018.1 - 4.3e-07 29.5 0.0 0.0036 16.6 0.0 3.1 1 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAP62018.1 - 1.8e-06 27.4 0.0 1.4e-05 24.4 0.0 2.2 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 OAP62018.1 - 0.00055 19.6 0.0 0.17 11.4 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase GIDA PF01134.22 OAP62018.1 - 0.0008 18.6 0.0 1.1 8.2 0.0 2.5 2 0 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.17 OAP62018.1 - 0.0041 16.4 0.0 0.18 11.0 0.0 2.3 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.6 OAP62018.1 - 0.0092 16.0 0.0 2.5 8.1 0.0 3.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding p450 PF00067.22 OAP62019.1 - 3e-55 187.8 0.0 2e-54 185.1 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 adh_short PF00106.25 OAP62020.1 - 5.8e-34 117.3 0.0 9.7e-34 116.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP62020.1 - 3.4e-30 105.3 0.0 5.3e-30 104.7 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Fungal_trans PF04082.18 OAP62020.1 - 1.6e-05 24.1 0.1 2.9e-05 23.3 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain KR PF08659.10 OAP62020.1 - 0.033 14.1 0.1 7 6.5 0.0 2.7 3 0 0 3 3 3 0 KR domain NAD_binding_8 PF13450.6 OAP62021.1 - 7.3e-12 45.4 0.0 2.2e-11 43.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.19 OAP62021.1 - 1.9e-10 39.8 0.0 7.4e-10 37.9 0.0 1.8 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OAP62021.1 - 1.1e-05 24.9 0.0 0.00016 21.0 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAP62021.1 - 0.0015 17.7 0.0 0.029 13.5 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 OAP62021.1 - 0.0066 15.7 0.0 0.22 10.7 0.0 2.2 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.14 OAP62021.1 - 0.019 14.2 0.0 0.8 8.9 0.0 2.7 2 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase MetallophosC PF16370.5 OAP62021.1 - 0.023 14.9 1.3 0.023 14.9 1.3 1.7 2 0 0 2 2 2 0 C terminal of Calcineurin-like phosphoesterase DUF4188 PF13826.6 OAP62021.1 - 0.03 14.7 0.4 2.8 8.3 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4188) NAD_binding_9 PF13454.6 OAP62021.1 - 0.033 14.2 0.0 0.91 9.5 0.0 2.8 3 0 0 3 3 3 0 FAD-NAD(P)-binding DAO PF01266.24 OAP62021.1 - 0.075 12.6 0.0 0.34 10.5 0.0 2.1 1 1 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 OAP62021.1 - 0.12 11.1 0.0 0.21 10.3 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein adh_short PF00106.25 OAP62022.1 - 2.3e-37 128.3 0.0 4e-37 127.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP62022.1 - 6.4e-28 97.9 0.0 9.4e-28 97.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP62022.1 - 5e-07 29.8 0.9 1.6e-05 24.9 0.9 2.7 1 1 0 1 1 1 1 KR domain DFP PF04127.15 OAP62022.1 - 0.0046 16.8 0.0 0.0068 16.3 0.0 1.2 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein Eno-Rase_NADH_b PF12242.8 OAP62022.1 - 0.011 15.5 0.9 0.069 12.9 0.1 2.6 3 1 1 4 4 4 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.21 OAP62022.1 - 0.11 12.0 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Abhydrolase_3 PF07859.13 OAP62023.1 - 3.8e-49 167.4 0.5 5.2e-49 167.0 0.5 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 OAP62023.1 - 7.7e-07 28.3 0.3 1.8e-06 27.2 0.3 1.5 1 1 0 1 1 1 1 Carboxylesterase family p450 PF00067.22 OAP62024.1 - 1.8e-55 188.5 0.0 2.7e-55 187.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.18 OAP62024.1 - 2.1e-29 102.4 2.6 3.6e-29 101.6 2.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Peptidase_S15 PF02129.18 OAP62025.1 - 1.1e-33 117.0 5.8 2.5e-30 106.0 5.8 2.9 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 OAP62025.1 - 2.4e-30 106.1 0.0 3.6e-30 105.6 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain DUF3362 PF11842.8 OAP62025.1 - 0.25 11.7 0.2 0.4 11.0 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3362) adh_short_C2 PF13561.6 OAP62026.1 - 9.3e-62 208.6 0.0 1.1e-61 208.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP62026.1 - 1.1e-50 171.8 0.0 1.4e-50 171.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAP62026.1 - 7.8e-06 25.9 0.0 1.5e-05 25.0 0.0 1.4 1 1 0 1 1 1 1 KR domain 2-Hacid_dh_C PF02826.19 OAP62026.1 - 0.014 14.7 0.1 2 7.8 0.1 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 OAP62026.1 - 0.069 12.4 0.2 0.098 11.9 0.2 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain AdoHcyase_NAD PF00670.21 OAP62026.1 - 0.07 13.2 0.1 0.093 12.8 0.1 1.3 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Acyl-CoA_dh_1 PF00441.24 OAP62027.1 - 6.2e-34 117.4 0.4 9.8e-34 116.7 0.4 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 OAP62027.1 - 3.1e-23 81.8 0.1 5.6e-23 81.0 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 OAP62027.1 - 2.2e-18 67.0 0.0 5.8e-18 65.6 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 OAP62027.1 - 0.0014 18.9 0.1 0.0022 18.3 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Pox_T4_N PF04491.12 OAP62027.1 - 0.08 12.8 0.1 0.18 11.7 0.1 1.5 1 0 0 1 1 1 0 Poxvirus T4 protein, N terminus Abhydrolase_1 PF00561.20 OAP62028.1 - 3.4e-20 72.8 0.1 2.7e-16 60.0 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAP62028.1 - 6.8e-16 59.5 0.6 8.1e-16 59.3 0.6 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAP62028.1 - 0.00026 20.4 0.0 0.00073 18.9 0.0 1.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Aa_trans PF01490.18 OAP62029.1 - 1.3e-26 93.3 37.7 2e-26 92.6 37.7 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Catalase PF00199.19 OAP62030.1 - 8.8e-119 397.0 0.0 1.2e-118 396.6 0.0 1.1 1 0 0 1 1 1 1 Catalase Catalase_C PF18011.1 OAP62030.1 - 1.5e-28 99.4 0.0 3e-28 98.4 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain found in long catalases Catalase-rel PF06628.12 OAP62030.1 - 2.6e-08 33.9 0.0 5.8e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive MFS_1 PF07690.16 OAP62033.1 - 2.5e-39 135.2 26.5 2.5e-39 135.2 26.5 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 OAP62033.1 - 0.0013 17.1 9.2 0.014 13.7 6.6 2.4 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family TPP_enzyme_N PF02776.18 OAP62034.1 - 2.4e-35 121.7 0.4 5.5e-33 114.0 0.1 2.6 2 1 0 2 2 2 2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 OAP62034.1 - 1.1e-18 67.4 0.0 2.8e-18 66.1 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 OAP62034.1 - 6e-11 42.2 0.0 1.2e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TauD PF02668.16 OAP62035.1 - 3.4e-56 191.0 2.6 3.9e-56 190.8 2.6 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Lactamase_B PF00753.27 OAP62036.1 - 2.8e-10 40.5 2.1 3.5e-10 40.2 2.0 1.4 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OAP62036.1 - 0.001 18.7 0.0 0.002 17.7 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Sugar_tr PF00083.24 OAP62037.1 - 7.2e-85 285.5 26.5 8.3e-85 285.3 26.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP62037.1 - 7.9e-31 107.3 45.5 1.3e-28 100.0 25.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily SnoaL_4 PF13577.6 OAP62038.1 - 7.5e-12 45.5 4.3 9.7e-12 45.1 4.3 1.1 1 0 0 1 1 1 1 SnoaL-like domain DUF2605 PF10792.9 OAP62038.1 - 0.024 14.6 0.1 0.034 14.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2605) Lzipper-MIP1 PF14389.6 OAP62038.1 - 0.083 13.2 0.1 0.13 12.6 0.1 1.3 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 SnoaL_2 PF12680.7 OAP62038.1 - 0.13 13.0 2.7 0.38 11.4 2.7 2.0 1 1 0 1 1 1 0 SnoaL-like domain Rv2175c_C PF18367.1 OAP62038.1 - 0.13 12.4 0.6 2.2 8.5 0.0 2.8 2 1 1 3 3 3 0 Rv2175c C-terminal domain of unknown function AHSA1 PF08327.11 OAP62038.1 - 0.15 12.3 2.2 1.3 9.3 0.2 2.2 2 0 0 2 2 2 0 Activator of Hsp90 ATPase homolog 1-like protein Oxidored_FMN PF00724.20 OAP62039.1 - 5.5e-61 206.7 0.0 6.9e-61 206.4 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family GST_N PF02798.20 OAP62040.1 - 1.1e-07 32.0 0.0 1.8e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OAP62040.1 - 7e-07 29.5 0.0 1.2e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 OAP62040.1 - 7.5e-07 29.5 0.0 1.2e-06 28.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OAP62040.1 - 0.0038 17.4 0.0 0.0061 16.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain EthD PF07110.11 OAP62041.1 - 4.4e-21 75.8 0.1 5.5e-21 75.5 0.1 1.1 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 OAP62041.1 - 2.4e-07 31.2 0.0 3.1e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Methylmuconolactone methyl-isomerase Speriolin_C PF15059.6 OAP62041.1 - 0.0061 16.7 0.0 0.0077 16.4 0.0 1.2 1 0 0 1 1 1 1 Speriolin C-terminus adh_short PF00106.25 OAP62042.1 - 3.7e-39 134.2 0.2 4.5e-39 133.9 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP62042.1 - 2.6e-26 92.6 0.1 8.9e-26 90.9 0.1 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP62042.1 - 8.5e-12 45.3 0.1 1.2e-11 44.9 0.1 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OAP62042.1 - 6.5e-09 35.3 0.1 7.5e-09 35.1 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 OAP62042.1 - 1.6e-06 27.7 0.1 6e-06 25.9 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OAP62042.1 - 0.00044 19.4 0.1 0.00057 19.0 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Ldh_1_N PF00056.23 OAP62042.1 - 0.0005 20.2 0.4 0.0016 18.6 0.1 1.8 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 OAP62042.1 - 0.012 15.1 0.0 0.019 14.3 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase ThiF PF00899.21 OAP62042.1 - 0.015 14.7 0.4 0.027 13.8 0.4 1.3 1 0 0 1 1 1 0 ThiF family NAD_binding_10 PF13460.6 OAP62042.1 - 0.098 12.5 0.1 0.19 11.6 0.1 1.4 1 1 0 1 1 1 0 NAD(P)H-binding RmlD_sub_bind PF04321.17 OAP62042.1 - 0.15 11.1 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain ABM PF03992.16 OAP62043.1 - 0.0071 16.4 0.3 0.015 15.4 0.3 1.5 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase ORC6 PF05460.13 OAP62043.1 - 0.088 12.1 0.3 0.13 11.6 0.3 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Caveolin PF01146.17 OAP62043.1 - 0.11 12.4 0.1 0.15 12.0 0.1 1.2 1 0 0 1 1 1 0 Caveolin EHN PF06441.12 OAP62044.1 - 2.7e-37 127.4 0.4 2e-35 121.4 0.0 2.3 2 0 0 2 2 2 2 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 OAP62044.1 - 2.1e-12 47.2 0.1 3.2e-12 46.6 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Aldo_ket_red PF00248.21 OAP62045.1 - 2.3e-47 161.6 0.0 2.6e-47 161.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family FAD_binding_3 PF01494.19 OAP62046.1 - 8.7e-75 252.1 0.0 1.3e-74 251.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain adh_short PF00106.25 OAP62046.1 - 1.7e-27 96.1 0.2 4e-27 94.9 0.1 1.6 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP62046.1 - 9e-19 67.9 0.0 1.5e-18 67.2 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP62046.1 - 0.00026 21.0 0.0 0.00049 20.1 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAP62046.1 - 0.00035 20.1 0.1 0.0053 16.2 0.1 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 OAP62046.1 - 0.0059 16.5 0.1 0.011 15.6 0.1 1.5 1 1 0 1 1 1 1 NAD(P)H-binding TrkA_N PF02254.18 OAP62046.1 - 0.072 13.4 0.1 0.14 12.4 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain adh_short PF00106.25 OAP62047.1 - 7.4e-27 94.1 0.2 1.1e-26 93.5 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP62047.1 - 5.2e-22 78.6 0.0 6.5e-22 78.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 OAP62047.1 - 3.7e-05 23.3 0.6 0.00078 19.0 0.6 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 OAP62047.1 - 0.00062 19.7 0.0 0.00089 19.2 0.0 1.4 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 OAP62047.1 - 0.0045 16.4 0.1 1.3 8.3 0.1 2.2 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 OAP62047.1 - 0.055 13.4 0.1 0.12 12.2 0.1 1.9 1 1 0 1 1 1 0 NAD(P)H-binding MT PF12777.7 OAP62047.1 - 0.069 12.2 0.0 0.097 11.7 0.0 1.3 1 0 0 1 1 1 0 Microtubule-binding stalk of dynein motor Pro_CA PF00484.19 OAP62048.1 - 3.3e-12 47.0 0.0 4.6e-12 46.5 0.0 1.2 1 0 0 1 1 1 1 Carbonic anhydrase ARID PF01388.21 OAP62050.1 - 4.9e-20 72.0 0.1 1.3e-19 70.6 0.1 1.8 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain Rhodanese PF00581.20 OAP62052.1 - 4.1e-11 43.3 0.0 9.3e-11 42.2 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain PNP_UDP_1 PF01048.20 OAP62053.1 - 1.9e-09 37.1 0.3 2.4e-09 36.8 0.3 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily DUF2011 PF09428.10 OAP62054.1 - 1.2e-19 70.3 0.0 3.2e-19 69.0 0.0 1.8 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2011) PBP_sp32 PF07222.12 OAP62054.1 - 3.3 7.1 6.5 6.4 6.2 6.5 1.4 1 0 0 1 1 1 0 Proacrosin binding protein sp32 ELFV_dehydrog PF00208.21 OAP62055.1 - 3.6e-67 226.6 0.0 6.4e-67 225.8 0.0 1.4 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 OAP62055.1 - 3.6e-18 64.6 0.1 8.8e-13 46.7 0.0 2.1 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.18 OAP62055.1 - 0.019 14.9 0.0 0.072 13.0 0.0 1.9 2 0 0 2 2 2 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain STIMATE PF12400.8 OAP62056.1 - 7.3e-41 139.6 1.0 1.3e-40 138.9 1.0 1.4 1 0 0 1 1 1 1 STIMATE family ABC2_membrane_3 PF12698.7 OAP62056.1 - 1.7 7.6 8.5 0.089 11.9 0.8 2.4 2 1 0 2 2 2 0 ABC-2 family transporter protein Peptidase_M48_N PF16491.5 OAP62056.1 - 4.4 7.2 6.8 4.7 7.1 0.6 2.4 3 0 0 3 3 3 0 CAAX prenyl protease N-terminal, five membrane helices Vps62 PF06101.11 OAP62057.1 - 4.4e-11 41.8 1.2 4.4e-11 41.8 1.2 1.8 2 0 0 2 2 2 1 Vacuolar protein sorting-associated protein 62 DUF1302 PF06980.11 OAP62057.1 - 0.044 12.4 0.3 0.066 11.8 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1302) TFIIIC_sub6 PF10419.9 OAP62058.1 - 2.8e-06 27.1 0.0 8.1e-06 25.6 0.0 1.8 1 0 0 1 1 1 1 TFIIIC subunit triple barrel domain AIRC PF00731.20 OAP62059.1 - 5.3e-57 191.5 1.2 1e-56 190.7 1.2 1.4 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.22 OAP62059.1 - 1.2e-49 168.2 0.0 1.8e-49 167.6 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain PurK_C PF17769.1 OAP62059.1 - 9e-19 66.9 0.0 1.9e-18 65.9 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain Dala_Dala_lig_C PF07478.13 OAP62059.1 - 0.00046 19.8 0.0 0.001 18.6 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus AlaDh_PNT_C PF01262.21 OAP62059.1 - 0.017 14.4 0.1 0.04 13.2 0.1 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain RRM_1 PF00076.22 OAP62060.1 - 8.6e-18 63.9 0.1 1.2e-17 63.5 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OAP62060.1 - 0.00039 20.0 0.0 0.00049 19.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) JmjC PF02373.22 OAP62061.1 - 1.4e-09 38.4 0.1 7.6e-09 36.0 0.1 2.3 1 1 0 1 1 1 1 JmjC domain, hydroxylase PHD PF00628.29 OAP62061.1 - 5.7e-09 35.7 7.6 5.7e-09 35.7 7.6 2.2 3 0 0 3 3 3 1 PHD-finger JHD PF17811.1 OAP62061.1 - 1.1e-07 32.3 0.9 1.9e-07 31.6 0.2 1.8 2 0 0 2 2 2 1 Jumonji helical domain Cupin_8 PF13621.6 OAP62061.1 - 7.7e-06 25.8 0.0 2.1e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 Cupin-like domain PHD_Oberon PF07227.11 OAP62061.1 - 0.0016 18.3 2.9 0.0039 17.1 2.9 1.6 1 0 0 1 1 1 1 PHD - plant homeodomain finger protein PHD_2 PF13831.6 OAP62061.1 - 0.0059 16.1 3.1 0.016 14.7 3.1 1.8 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H_2 PF13832.6 OAP62061.1 - 3 8.1 7.3 0.82 9.9 3.2 2.1 2 0 0 2 2 2 0 PHD-zinc-finger like domain C1_1 PF00130.22 OAP62061.1 - 3.7 7.5 10.5 0.054 13.4 2.4 2.1 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn_clus PF00172.18 OAP62061.1 - 5.4 7.2 32.6 0.061 13.5 3.4 4.2 3 1 1 4 4 4 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Mito_carr PF00153.27 OAP62062.1 - 1.2e-47 159.7 0.3 2.5e-16 59.3 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Selenoprotein_S PF06936.11 OAP62062.1 - 2.1 8.1 5.5 0.22 11.3 0.6 1.8 2 0 0 2 2 2 0 Selenoprotein S (SelS) YtxH PF12732.7 OAP62062.1 - 3.7 8.1 12.0 8.4 7.0 3.8 3.2 3 0 0 3 3 3 0 YtxH-like protein TMEM208_SND2 PF05620.11 OAP62063.1 - 7.9e-52 175.4 0.3 8.8e-52 175.3 0.3 1.0 1 0 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 TPR_1 PF00515.28 OAP62064.1 - 6e-38 127.1 14.7 1.3e-07 31.1 0.2 8.6 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_2 PF07719.17 OAP62064.1 - 6.8e-34 113.2 20.5 9.3e-07 28.5 0.2 9.0 9 0 0 9 9 9 7 Tetratricopeptide repeat ANAPC3 PF12895.7 OAP62064.1 - 9.1e-30 102.7 18.6 2.2e-19 69.5 0.3 4.8 2 1 2 5 5 5 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 OAP62064.1 - 1.1e-22 78.2 7.9 0.0027 17.8 0.0 8.5 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_16 PF13432.6 OAP62064.1 - 6.6e-21 74.7 12.7 1.1e-09 38.8 2.2 7.0 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_11 PF13414.6 OAP62064.1 - 4.3e-20 71.1 7.0 9.4e-07 28.4 5.8 9.1 8 2 2 10 10 10 3 TPR repeat TPR_19 PF14559.6 OAP62064.1 - 1.6e-18 67.0 15.8 8.2e-05 23.0 0.0 6.8 6 2 1 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.6 OAP62064.1 - 3.4e-17 61.7 19.6 0.012 16.3 0.0 9.6 5 1 5 10 10 10 6 Tetratricopeptide repeat TPR_17 PF13431.6 OAP62064.1 - 2.1e-16 59.0 10.2 0.045 14.1 0.2 8.4 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_12 PF13424.6 OAP62064.1 - 2.8e-13 50.0 16.2 0.00069 19.9 0.1 7.1 5 1 2 7 7 6 5 Tetratricopeptide repeat TPR_9 PF13371.6 OAP62064.1 - 1.7e-11 44.1 5.3 0.013 15.6 0.1 5.7 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 OAP62064.1 - 5.5e-08 33.0 11.5 3.3 8.6 0.0 8.5 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_7 PF13176.6 OAP62064.1 - 1.7e-07 30.7 11.4 0.14 12.3 0.0 6.7 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_10 PF13374.6 OAP62064.1 - 0.001 18.9 5.5 3.3 7.7 0.1 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_15 PF13429.6 OAP62064.1 - 0.015 14.5 11.8 0.86 8.8 0.0 4.8 2 2 1 4 4 4 0 Tetratricopeptide repeat YfiO PF13525.6 OAP62064.1 - 0.025 14.3 1.7 0.19 11.4 0.3 2.5 2 0 0 2 2 2 0 Outer membrane lipoprotein ChAPs PF09295.10 OAP62064.1 - 0.037 13.0 0.2 3.1 6.7 0.0 3.3 2 2 1 4 4 4 0 ChAPs (Chs5p-Arf1p-binding proteins) TRIF-NTD PF17798.1 OAP62064.1 - 0.22 11.6 1.5 1.1 9.4 0.1 3.0 3 0 0 3 3 3 0 TRIF N-terminal domain Apolipoprotein PF01442.18 OAP62065.1 - 1.5 8.6 38.4 0.13 12.1 1.4 7.4 5 3 0 5 5 5 0 Apolipoprotein A1/A4/E domain RINGv PF12906.7 OAP62066.1 - 3.2e-16 59.2 7.9 5.6e-16 58.4 7.9 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 OAP62066.1 - 0.0012 19.2 7.3 0.0021 18.3 7.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-ANAPC11 PF12861.7 OAP62066.1 - 0.25 11.4 4.4 0.22 11.6 2.1 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF1932 PF09130.11 OAP62068.1 - 4.8e-27 93.7 0.0 1.2e-26 92.5 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1932) F420_oxidored PF03807.17 OAP62068.1 - 0.00025 21.6 0.0 0.0015 19.1 0.0 2.3 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 OAP62068.1 - 0.0023 18.1 0.0 0.023 14.9 0.1 2.5 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.23 OAP62068.1 - 0.11 12.4 0.0 1.5 8.8 0.0 2.3 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 2-Hacid_dh_C PF02826.19 OAP62068.1 - 0.14 11.5 0.3 1.8 7.9 0.1 2.2 1 1 1 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ILVD_EDD PF00920.21 OAP62069.1 - 4.1e-155 517.3 0.2 4.7e-155 517.1 0.2 1.0 1 0 0 1 1 1 1 Dehydratase family Glyoxalase PF00903.25 OAP62070.1 - 2.6e-40 137.6 0.0 6e-19 68.5 0.0 2.1 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 OAP62070.1 - 3.1e-15 56.4 0.0 1.1e-06 28.9 0.0 3.7 1 1 2 3 3 3 3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 OAP62070.1 - 4.3e-06 27.5 0.0 0.088 13.6 0.0 2.8 2 2 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_3 PF13468.6 OAP62070.1 - 9.1e-06 25.9 0.0 0.14 12.3 0.0 3.3 1 1 1 2 2 2 2 Glyoxalase-like domain MoaF PF10703.9 OAP62070.1 - 0.00065 19.6 0.1 0.052 13.5 0.0 2.4 2 0 0 2 2 2 1 MoaF N-terminal domain Glyoxalase_2 PF12681.7 OAP62070.1 - 0.0014 18.6 1.0 1.2 9.1 0.0 3.7 4 0 0 4 4 4 1 Glyoxalase-like domain DUF1338 PF07063.13 OAP62070.1 - 0.0074 15.5 0.0 0.3 10.2 0.0 2.9 4 0 0 4 4 4 1 Domain of unknown function (DUF1338) HTH_54 PF18607.1 OAP62070.1 - 0.011 15.7 0.0 2.2 8.4 0.0 2.3 2 0 0 2 2 2 0 ParA helix turn helix domain NIL PF09383.10 OAP62070.1 - 0.18 11.7 0.0 6.1 6.8 0.0 2.2 2 0 0 2 2 2 0 NIL domain Fe-ADH PF00465.19 OAP62071.1 - 5.2e-103 344.7 0.0 6.2e-103 344.4 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 OAP62071.1 - 6.8e-15 55.5 0.0 6e-11 42.5 0.0 2.3 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Peripla_BP_6 PF13458.6 OAP62071.1 - 0.033 13.8 0.0 0.062 13.0 0.0 1.3 1 0 0 1 1 1 0 Periplasmic binding protein Toprim_3 PF13362.6 OAP62071.1 - 0.1 13.0 0.0 0.42 11.0 0.0 1.9 2 0 0 2 2 2 0 Toprim domain 2-Hacid_dh_C PF02826.19 OAP62072.1 - 1.4e-54 184.2 0.0 2.1e-54 183.5 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 OAP62072.1 - 1.9e-35 121.5 0.1 3.9e-35 120.4 0.1 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain XdhC_C PF13478.6 OAP62072.1 - 0.015 15.8 0.0 0.042 14.4 0.0 1.8 1 0 0 1 1 1 0 XdhC Rossmann domain IlvN PF07991.12 OAP62072.1 - 0.015 14.9 0.0 0.03 13.9 0.0 1.5 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain AdoHcyase_NAD PF00670.21 OAP62072.1 - 0.021 14.9 0.1 0.046 13.8 0.1 1.5 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ACT PF01842.25 OAP62072.1 - 0.054 13.3 0.2 0.48 10.3 0.2 2.7 1 1 0 1 1 1 0 ACT domain Glyco_hydro_43 PF04616.14 OAP62073.1 - 8.3e-68 228.8 0.0 1.1e-67 228.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 OAP62073.1 - 8.2e-11 42.0 0.0 1.4e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain Glyco_hydro_32C PF08244.12 OAP62073.1 - 0.18 11.8 0.0 0.32 11.0 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 32 C terminal Complex1_30kDa PF00329.19 OAP62074.1 - 2.5e-45 154.1 0.0 3.4e-45 153.6 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit zf-RING_4 PF14570.6 OAP62075.1 - 5.7e-18 64.4 13.3 1e-17 63.6 13.3 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 OAP62075.1 - 7.3e-08 32.1 7.7 1.4e-07 31.3 7.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.22 OAP62075.1 - 6.5e-05 22.7 0.0 0.00016 21.4 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RING_2 PF13639.6 OAP62075.1 - 0.00015 22.0 11.2 0.00034 20.9 11.2 1.6 1 0 0 1 1 1 1 Ring finger domain Rtf2 PF04641.12 OAP62075.1 - 0.00025 20.5 4.0 0.00025 20.5 4.0 2.7 3 0 0 3 3 3 1 Rtf2 RING-finger Prok-RING_4 PF14447.6 OAP62075.1 - 0.0015 18.4 9.6 0.078 12.8 10.2 2.3 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-TFIIIC PF12660.7 OAP62075.1 - 0.051 13.5 0.6 0.11 12.5 0.6 1.6 1 0 0 1 1 1 0 Putative zinc-finger of transcription factor IIIC complex zf-RING_5 PF14634.6 OAP62075.1 - 0.18 11.8 11.7 0.35 10.9 11.7 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.25 OAP62075.1 - 0.3 11.0 12.1 0.6 10.0 12.1 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.21 OAP62075.1 - 0.62 10.2 6.2 2.2 8.5 6.1 1.9 1 1 0 1 1 1 0 FYVE zinc finger Baculo_IE-1 PF05290.11 OAP62075.1 - 0.62 10.0 6.7 1.2 9.1 6.7 1.4 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) DZR PF12773.7 OAP62075.1 - 0.85 9.7 10.2 9.2 6.4 10.5 2.3 1 1 1 2 2 2 0 Double zinc ribbon zf-C3HC4_2 PF13923.6 OAP62075.1 - 2.9 7.8 11.2 6.1 6.8 11.2 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) GCN5L1 PF06320.13 OAP62076.1 - 0.25 11.5 14.7 0.26 11.4 0.5 3.1 2 1 1 3 3 3 0 GCN5-like protein 1 (GCN5L1) zf-C3HC PF07967.13 OAP62079.1 - 7.7e-31 106.9 9.1 1e-28 100.0 0.1 3.5 3 1 0 3 3 3 2 C3HC zinc finger-like Rsm1 PF08600.10 OAP62079.1 - 6.4e-17 61.5 1.1 1.1e-15 57.5 0.2 2.8 3 0 0 3 3 3 1 Rsm1-like BIR PF00653.21 OAP62079.1 - 0.00053 20.6 2.0 0.037 14.7 0.1 2.4 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain zf-TFIIB PF13453.6 OAP62079.1 - 0.003 16.9 0.9 0.0087 15.4 0.9 1.7 1 0 0 1 1 1 1 Transcription factor zinc-finger RNF220 PF15926.5 OAP62079.1 - 0.34 10.5 5.7 0.076 12.6 0.7 2.4 2 1 1 3 3 3 0 E3 ubiquitin-protein ligase RNF220 Mito_carr PF00153.27 OAP62080.1 - 8.1e-54 179.5 2.3 6.7e-18 64.4 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Atx10homo_assoc PF09759.9 OAP62081.1 - 8e-28 96.4 0.1 5.5e-27 93.7 0.0 2.4 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain zf-C2H2_4 PF13894.6 OAP62082.1 - 3.8e-06 27.3 22.4 0.0024 18.6 1.4 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OAP62082.1 - 0.00038 20.7 1.9 0.00038 20.7 1.9 3.6 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2 PF00096.26 OAP62082.1 - 0.0013 19.1 23.3 0.024 15.1 3.9 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 OAP62082.1 - 2.8 7.8 17.6 2.7 7.9 2.1 4.0 3 1 0 3 3 3 0 C2H2-type zinc-finger domain DUF629 PF04780.12 OAP62082.1 - 8.9 4.7 6.5 6.9 5.1 4.3 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF629) adh_short PF00106.25 OAP62083.1 - 1.1e-21 77.2 0.1 1.3e-21 76.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP62083.1 - 1.6e-21 77.0 0.3 2.1e-21 76.6 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 OAP62083.1 - 0.00014 21.4 0.0 0.00024 20.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 OAP62083.1 - 0.00062 19.7 0.2 0.00095 19.1 0.2 1.3 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 OAP62083.1 - 0.044 13.7 0.3 0.077 12.9 0.3 1.5 1 1 0 1 1 1 0 KR domain DIOX_N PF14226.6 OAP62085.1 - 2.1e-19 70.4 0.0 5.5e-19 69.1 0.0 1.7 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OAP62085.1 - 1.2e-14 54.6 0.0 2.2e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily NUDE_C PF04880.13 OAP62086.1 - 2.6e-49 168.1 10.0 2.6e-49 168.1 10.0 4.3 2 2 4 6 6 4 1 NUDE protein, C-terminal conserved region ZapB PF06005.12 OAP62086.1 - 0.0073 16.7 10.5 0.0073 16.7 10.5 4.8 2 1 2 4 4 4 2 Cell division protein ZapB Tropomyosin_1 PF12718.7 OAP62086.1 - 0.43 10.7 38.5 0.46 10.6 24.8 3.2 2 1 1 3 3 3 0 Tropomyosin like MAD PF05557.13 OAP62086.1 - 0.65 8.3 32.8 55 1.9 32.8 2.2 1 1 0 1 1 1 0 Mitotic checkpoint protein TPR_MLP1_2 PF07926.12 OAP62086.1 - 0.7 10.0 41.7 1.3 9.1 10.5 4.1 2 1 3 5 5 5 0 TPR/MLP1/MLP2-like protein Fez1 PF06818.15 OAP62086.1 - 1.6 9.2 32.4 0.91 9.9 17.5 2.5 2 1 1 3 3 3 0 Fez1 Atg14 PF10186.9 OAP62086.1 - 3.4 6.6 34.5 0.18 10.9 12.4 2.5 2 1 1 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 PSII_Pbs27 PF13326.6 OAP62086.1 - 3.5 8.0 9.5 0.19 12.0 2.1 2.2 2 0 0 2 2 2 0 Photosystem II Pbs27 Tho2 PF11262.8 OAP62086.1 - 3.5 6.7 25.0 0.19 10.9 9.0 2.1 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 ERM PF00769.19 OAP62086.1 - 5.2 6.8 39.4 0.2 11.4 19.3 2.2 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Fmp27_WPPW PF10359.9 OAP62086.1 - 7.9 5.2 21.4 1.3 7.7 15.8 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain YabA PF06156.13 OAP62086.1 - 9.4 6.9 25.3 0.067 13.8 7.1 3.1 1 1 1 2 2 1 0 Initiation control protein YabA Isochorismatase PF00857.20 OAP62087.1 - 1.6e-48 165.2 0.0 2e-48 164.9 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family NUC153 PF08159.12 OAP62088.1 - 3.8e-12 45.8 0.5 1.1e-11 44.3 0.5 1.8 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.32 OAP62088.1 - 0.023 15.5 0.1 63 4.7 0.0 4.0 4 0 0 4 4 4 0 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAP62088.1 - 0.036 14.4 0.0 0.31 11.4 0.0 2.5 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Med13_C PF06333.12 OAP62089.1 - 3.6e-83 279.6 1.2 3.6e-83 279.6 1.2 2.6 2 0 0 2 2 2 1 Mediator complex subunit 13 C-terminal domain Med13_N PF11597.8 OAP62089.1 - 1.2e-69 235.1 0.4 1.2e-69 235.1 0.4 1.6 2 0 0 2 2 2 1 Mediator complex subunit 13 N-terminal MID_MedPIWI PF18296.1 OAP62089.1 - 1.5e-10 41.3 8.3 7.5e-07 29.2 0.0 3.2 3 1 1 4 4 4 2 MID domain of medPIWI FAM104 PF15434.6 OAP62089.1 - 0.11 13.0 1.5 0.41 11.2 1.5 1.9 1 0 0 1 1 1 0 Family 104 MFS_1 PF07690.16 OAP62090.1 - 1.5e-14 53.7 51.1 6.3e-14 51.7 49.6 2.7 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 OAP62090.1 - 6.3e-07 28.2 22.3 9.6e-07 27.6 22.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) dCMP_cyt_deam_1 PF00383.23 OAP62093.1 - 1.5e-27 95.4 1.3 2.2e-27 94.9 1.3 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 OAP62093.1 - 1.2e-10 41.3 0.1 1.6e-10 40.9 0.1 1.2 1 0 0 1 1 1 1 MafB19-like deaminase Pex14_N PF04695.13 OAP62093.1 - 0.014 16.0 0.1 0.02 15.5 0.1 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region APOBEC4_like PF18774.1 OAP62093.1 - 0.11 12.4 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 APOBEC4-like -AID/APOBEC-deaminase AAA_18 PF13238.6 OAP62094.1 - 0.0037 17.8 0.0 0.014 15.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 OAP62094.1 - 0.0066 16.6 0.0 0.0066 16.6 0.0 1.3 1 1 0 1 1 1 1 AAA domain Lambda_CIII PF02061.16 OAP62094.1 - 0.031 14.3 0.0 0.061 13.4 0.0 1.4 1 0 0 1 1 1 0 Lambda Phage CIII CoaE PF01121.20 OAP62094.1 - 0.054 13.2 0.0 0.088 12.5 0.0 1.3 1 0 0 1 1 1 0 Dephospho-CoA kinase ATG7_N PF16420.5 OAP62095.1 - 6.6e-113 377.3 0.0 9.2e-113 376.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 OAP62095.1 - 5.9e-45 153.5 0.0 8.9e-45 152.9 0.0 1.1 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 OAP62095.1 - 0.18 11.9 0.0 0.42 10.7 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FtsJ PF01728.19 OAP62096.1 - 8.8e-55 185.5 0.0 1e-54 185.3 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF4611 PF15387.6 OAP62097.1 - 2.5 8.4 12.6 0.27 11.5 2.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) HMMR_N PF15905.5 OAP62098.1 - 0.003 17.1 32.2 0.003 17.1 32.2 1.5 1 1 1 2 2 2 1 Hyaluronan mediated motility receptor N-terminal FAM76 PF16046.5 OAP62098.1 - 0.0036 16.7 18.9 0.0047 16.3 18.9 1.2 1 0 0 1 1 1 1 FAM76 protein PDE4_UCR PF18100.1 OAP62098.1 - 0.0048 17.5 5.5 0.0048 17.5 5.5 2.3 1 1 1 2 2 2 1 Phosphodiesterase 4 upstream conserved regions (UCR) GAS PF13851.6 OAP62098.1 - 0.0084 15.5 34.8 0.0069 15.8 28.6 2.1 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding ATG16 PF08614.11 OAP62098.1 - 0.016 15.4 35.2 0.28 11.4 20.4 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.9 OAP62098.1 - 0.017 15.2 42.0 1.1 9.3 16.4 3.2 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 YgaB PF14182.6 OAP62098.1 - 0.017 15.5 6.0 0.017 15.5 6.0 3.3 2 1 0 2 2 1 0 YgaB-like protein HOOK PF05622.12 OAP62098.1 - 0.033 12.4 31.1 0.038 12.2 31.1 1.1 1 0 0 1 1 1 0 HOOK protein FlaC_arch PF05377.11 OAP62098.1 - 0.088 13.2 18.7 0.59 10.6 0.2 4.9 3 1 3 6 6 5 0 Flagella accessory protein C (FlaC) YabA PF06156.13 OAP62098.1 - 0.11 13.1 29.3 1.1 10.0 6.4 3.8 1 1 2 3 3 3 0 Initiation control protein YabA Filament PF00038.21 OAP62098.1 - 0.13 11.9 33.1 0.16 11.5 17.2 2.3 1 1 1 2 2 2 0 Intermediate filament protein Cnn_1N PF07989.11 OAP62098.1 - 0.26 11.5 33.6 0.51 10.5 4.9 4.9 2 1 4 6 6 6 0 Centrosomin N-terminal motif 1 Seryl_tRNA_N PF02403.22 OAP62098.1 - 0.29 11.4 29.2 0.071 13.4 9.3 3.2 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain KASH_CCD PF14662.6 OAP62098.1 - 0.35 10.7 36.5 2.1 8.2 17.3 2.3 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH KxDL PF10241.9 OAP62098.1 - 0.73 10.2 19.8 0.062 13.6 3.4 3.2 1 1 2 3 3 3 0 Uncharacterized conserved protein PRKG1_interact PF15898.5 OAP62098.1 - 0.84 10.6 34.9 4.2 8.3 9.9 3.4 1 1 3 4 4 4 0 cGMP-dependent protein kinase interacting domain Spc7 PF08317.11 OAP62098.1 - 0.89 8.4 36.4 0.14 11.0 20.4 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein THOC7 PF05615.13 OAP62098.1 - 0.99 9.7 36.5 7.5 6.8 20.1 3.0 1 1 2 3 3 3 0 Tho complex subunit 7 Uso1_p115_C PF04871.13 OAP62098.1 - 1.8 8.9 36.4 7.5 6.9 12.8 3.1 1 1 2 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF812 PF05667.11 OAP62098.1 - 2 7.2 29.0 2.7 6.8 29.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) APG6_N PF17675.1 OAP62098.1 - 2.9 8.4 46.5 0.059 13.9 10.7 3.1 1 1 2 3 3 3 0 Apg6 coiled-coil region DUF1664 PF07889.12 OAP62098.1 - 2.9 7.9 14.4 8.1 6.5 1.5 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) Atg14 PF10186.9 OAP62098.1 - 4.1 6.4 28.9 1.6 7.7 15.5 2.1 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF3450 PF11932.8 OAP62098.1 - 4.7 6.4 30.7 2.6 7.3 10.5 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) DUF4407 PF14362.6 OAP62098.1 - 5.7 6.2 21.3 7.9 5.7 21.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) FUSC PF04632.12 OAP62098.1 - 5.9 5.3 27.6 0.078 11.5 11.0 2.0 1 1 1 2 2 2 0 Fusaric acid resistance protein family HIP1_clath_bdg PF16515.5 OAP62098.1 - 7.8 7.2 38.5 0.082 13.5 5.9 3.7 1 1 3 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 MFS_1 PF07690.16 OAP62100.1 - 5.4e-38 130.8 21.8 7.7e-38 130.3 21.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily TMEM89 PF15098.6 OAP62100.1 - 0.096 12.9 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 TMEM89 protein family OST3_OST6 PF04756.13 OAP62102.1 - 3.5e-103 345.0 0.0 4.3e-103 344.7 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin PF00085.20 OAP62102.1 - 0.0033 17.4 0.0 0.0065 16.4 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin HXXEE PF13787.6 OAP62102.1 - 2.4 9.0 7.7 0.34 11.7 1.8 2.1 1 1 0 2 2 2 0 Protein of unknown function with HXXEE motif GrpE PF01025.19 OAP62103.1 - 0.29 10.8 4.8 0.46 10.1 4.8 1.3 1 0 0 1 1 1 0 GrpE ARS2 PF04959.13 OAP62104.1 - 4 7.8 8.1 0.36 11.2 1.3 2.5 2 1 0 2 2 2 0 Arsenite-resistance protein 2 Prenyltrans PF00432.21 OAP62105.1 - 1.8e-27 94.8 12.7 3.1e-06 26.8 0.6 5.7 5 1 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat MarR PF01047.22 OAP62105.1 - 0.14 12.1 0.0 1.2 9.1 0.0 2.4 3 0 0 3 3 3 0 MarR family eIF3_subunit PF08597.10 OAP62106.1 - 2.2e-67 227.5 35.6 2.4e-67 227.4 35.6 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit Peptidase_M56 PF05569.11 OAP62106.1 - 0.06 12.5 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 BlaR1 peptidase M56 Nop53 PF07767.11 OAP62106.1 - 8 5.7 36.3 9.7 5.5 0.3 2.1 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) Rrn6 PF10214.9 OAP62106.1 - 9.7 4.5 15.3 0.31 9.5 9.6 1.4 2 0 0 2 2 2 0 RNA polymerase I-specific transcription-initiation factor Enolase_C PF00113.22 OAP62107.1 - 5e-154 511.8 0.1 6.6e-154 511.4 0.1 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 OAP62107.1 - 1.2e-57 193.7 0.2 2.3e-57 192.8 0.1 1.6 2 0 0 2 2 2 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 OAP62107.1 - 4.1e-07 29.8 0.0 6.6e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 OAP62107.1 - 0.0051 16.0 0.6 0.15 11.2 0.1 2.6 3 0 0 3 3 3 1 Methylaspartate ammonia-lyase C-terminus VSP PF03302.13 OAP62107.1 - 0.1 11.4 0.2 0.16 10.8 0.2 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein AAA PF00004.29 OAP62108.1 - 6e-43 146.4 0.0 1.2e-42 145.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 OAP62108.1 - 8.6e-13 48.0 0.1 2.9e-11 43.2 0.0 2.4 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 OAP62108.1 - 1.9e-10 40.3 0.2 4.9e-10 39.0 0.0 1.8 2 0 0 2 2 1 1 AAA+ lid domain AAA_16 PF13191.6 OAP62108.1 - 2.4e-07 31.3 0.0 0.00012 22.5 0.1 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 OAP62108.1 - 1.8e-06 28.0 0.0 4.3e-05 23.5 0.0 2.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 OAP62108.1 - 2.2e-06 27.9 0.0 8e-06 26.1 0.0 2.0 3 0 0 3 3 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 OAP62108.1 - 7.5e-06 25.8 0.0 1.6e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 OAP62108.1 - 6.6e-05 23.5 0.1 0.0042 17.6 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 OAP62108.1 - 0.00019 21.7 0.0 0.0031 17.8 0.0 2.4 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 OAP62108.1 - 0.00041 19.6 0.0 0.0011 18.2 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_7 PF12775.7 OAP62108.1 - 0.00084 18.9 0.0 0.0016 18.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region TIP49 PF06068.13 OAP62108.1 - 0.0018 17.6 0.0 0.0033 16.7 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 OAP62108.1 - 0.0035 17.5 0.0 0.0095 16.1 0.0 1.8 2 0 0 2 2 1 1 AAA domain Prot_ATP_OB_N PF17758.1 OAP62108.1 - 0.0041 16.7 0.0 0.012 15.2 0.0 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB N-terminal domain Mg_chelatase PF01078.21 OAP62108.1 - 0.0044 16.4 0.0 0.0093 15.4 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TsaE PF02367.17 OAP62108.1 - 0.0054 16.7 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 OAP62108.1 - 0.0062 16.3 0.0 0.015 15.0 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein DUF4482 PF14818.6 OAP62108.1 - 0.0067 17.3 0.7 0.0067 17.3 0.7 1.8 2 0 0 2 2 1 1 Domain of unknown function (DUF4482) AAA_14 PF13173.6 OAP62108.1 - 0.0086 16.1 0.0 0.019 15.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 OAP62108.1 - 0.0087 15.8 0.0 0.027 14.2 0.0 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.11 OAP62108.1 - 0.0091 15.9 0.0 0.022 14.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 OAP62108.1 - 0.011 16.1 0.0 0.023 15.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_11 PF13086.6 OAP62108.1 - 0.02 14.7 0.5 0.32 10.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 OAP62108.1 - 0.03 14.0 0.0 0.087 12.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 OAP62108.1 - 0.031 13.6 0.7 0.12 11.7 0.0 2.2 3 0 0 3 3 3 0 KaiC Thymidylate_kin PF02223.17 OAP62108.1 - 0.045 13.4 0.0 6 6.5 0.0 2.7 3 0 0 3 3 2 0 Thymidylate kinase NACHT PF05729.12 OAP62108.1 - 0.073 13.0 0.1 0.19 11.7 0.0 1.7 2 0 0 2 2 2 0 NACHT domain PhoH PF02562.16 OAP62108.1 - 0.076 12.5 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 OAP62108.1 - 0.092 12.3 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 OAP62108.1 - 0.098 11.9 0.1 0.25 10.6 0.0 1.6 2 0 0 2 2 1 0 Zeta toxin AAA_28 PF13521.6 OAP62108.1 - 0.1 12.8 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 OAP62108.1 - 0.1 11.7 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_30 PF13604.6 OAP62108.1 - 0.11 12.2 0.0 0.28 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain OmpH PF03938.14 OAP62108.1 - 0.54 10.6 7.0 0.32 11.3 2.1 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DivIC PF04977.15 OAP62108.1 - 0.97 9.3 3.9 5.6 6.8 1.1 2.8 3 0 0 3 3 2 0 Septum formation initiator AAA_13 PF13166.6 OAP62108.1 - 2 7.0 4.4 29 3.1 0.9 2.7 2 1 1 3 3 3 0 AAA domain MFS_1 PF07690.16 OAP62109.1 - 1.4e-25 90.0 63.3 4.8e-21 75.1 48.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Gal4_dimer PF03902.13 OAP62110.1 - 0.033 14.3 0.1 0.34 11.1 0.0 2.2 2 0 0 2 2 2 0 Gal4-like dimerisation domain GAPES4 PF17157.4 OAP62110.1 - 0.11 13.0 0.1 0.24 11.8 0.1 1.6 1 0 0 1 1 1 0 Gammaproteobacterial periplasmic sensor domain Mitoc_mL59 PF18126.1 OAP62111.1 - 7.4e-51 171.8 3.0 1.3e-50 171.0 3.0 1.4 1 1 0 1 1 1 1 Mitochondrial ribosomal protein mL59 Suf PF05843.14 OAP62112.1 - 1.3e-06 28.7 4.3 0.00018 21.6 0.1 3.2 3 0 0 3 3 3 1 Suppressor of forked protein (Suf) TPR_14 PF13428.6 OAP62112.1 - 1.4e-06 28.7 5.1 0.36 11.8 0.1 6.8 6 4 3 9 9 9 2 Tetratricopeptide repeat TPR_19 PF14559.6 OAP62112.1 - 0.00088 19.7 1.2 22 5.6 0.0 4.2 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_15 PF13429.6 OAP62112.1 - 0.022 14.0 5.6 5.4 6.1 0.3 4.1 4 1 0 4 4 4 0 Tetratricopeptide repeat HAT PF02184.16 OAP62112.1 - 1.3 9.0 19.1 16 5.6 0.0 6.7 7 1 0 7 7 7 0 HAT (Half-A-TPR) repeat SIS PF01380.22 OAP62113.1 - 1.6e-58 196.2 0.0 2.9e-31 108.0 0.1 2.3 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 OAP62113.1 - 2.7e-18 66.5 0.0 5.5e-18 65.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 OAP62113.1 - 1.3e-11 44.5 0.0 3.1e-11 43.2 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 OAP62113.1 - 0.00045 19.2 0.0 0.0007 18.6 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glyco_transf_22 PF03901.17 OAP62114.1 - 5.1e-75 253.3 19.8 6.3e-75 253.0 19.8 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family BCHF PF07284.11 OAP62114.1 - 0.041 13.9 2.5 0.054 13.5 0.4 2.2 2 0 0 2 2 2 0 2-vinyl bacteriochlorophyllide hydratase (BCHF) ArfGap PF01412.18 OAP62115.1 - 3.8e-40 136.6 0.4 1e-39 135.3 0.4 1.7 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf CUE PF02845.16 OAP62115.1 - 0.1 12.3 0.1 0.19 11.4 0.1 1.5 1 0 0 1 1 1 0 CUE domain UBA PF00627.31 OAP62115.1 - 0.11 12.5 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 UBA/TS-N domain Zn-ribbon_8 PF09723.10 OAP62116.1 - 0.09 12.9 1.2 0.19 11.9 1.2 1.5 1 0 0 1 1 1 0 Zinc ribbon domain Rubredoxin_2 PF18073.1 OAP62116.1 - 0.56 10.0 6.4 1 9.1 1.1 2.3 2 0 0 2 2 2 0 Rubredoxin metal binding domain zf-Mss51 PF13824.6 OAP62116.1 - 0.96 9.6 5.9 3 8.0 0.9 3.4 2 1 1 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 Proteasome PF00227.26 OAP62117.1 - 1.8e-45 154.8 0.0 7.3e-32 110.4 0.0 2.2 1 1 1 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.9 OAP62117.1 - 5.7e-12 45.1 1.0 6.3e-12 44.9 0.0 1.6 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DUF5633 PF18656.1 OAP62117.1 - 5.1 7.1 5.7 1.3 9.0 1.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5633) DMRL_synthase PF00885.19 OAP62118.1 - 7.8e-54 181.3 0.1 1.1e-53 180.9 0.1 1.2 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase Aminotran_3 PF00202.21 OAP62119.1 - 2.1e-119 398.8 0.0 2.5e-119 398.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 OAP62119.1 - 0.0025 17.0 0.0 0.0046 16.2 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II OAM_dimer PF16554.5 OAP62119.1 - 0.046 14.2 0.0 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 Dimerisation domain of d-ornithine 4,5-aminomutase MPLKIP PF15502.6 OAP62120.1 - 1.1 9.5 4.3 0.87 9.9 0.6 2.7 2 1 1 3 3 3 0 M-phase-specific PLK1-interacting protein Syja_N PF02383.18 OAP62123.1 - 1.7e-75 254.3 0.0 5.4e-75 252.7 0.0 1.8 2 0 0 2 2 2 1 SacI homology domain Exo_endo_phos PF03372.23 OAP62123.1 - 8.8e-12 45.0 0.0 1.7e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family TPR_2 PF07719.17 OAP62125.1 - 4.5e-06 26.4 0.0 0.00058 19.8 0.0 3.9 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 OAP62125.1 - 1.7e-05 25.2 1.0 2.1 9.4 0.0 5.2 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 OAP62125.1 - 3.9e-05 23.2 0.0 0.033 13.9 0.0 2.9 2 0 0 2 2 2 2 TPR repeat TPR_9 PF13371.6 OAP62125.1 - 0.00013 22.1 0.8 0.004 17.3 0.1 3.4 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 OAP62125.1 - 0.0023 18.4 0.2 0.092 13.3 0.0 3.3 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 OAP62125.1 - 0.0029 17.4 0.2 0.03 14.1 0.0 2.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_20 PF14561.6 OAP62125.1 - 0.01 16.1 0.0 0.049 14.0 0.0 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 OAP62125.1 - 0.016 15.8 0.1 0.09 13.4 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 OAP62125.1 - 0.022 15.1 0.0 1.9 9.0 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat BTAD PF03704.17 OAP62125.1 - 0.032 14.7 0.1 0.16 12.4 0.0 2.2 1 1 0 1 1 1 0 Bacterial transcriptional activator domain TPR_8 PF13181.6 OAP62125.1 - 0.035 14.3 0.0 0.46 10.8 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat HrpJ PF07201.11 OAP62125.1 - 0.056 13.8 1.1 0.23 11.8 0.0 2.3 2 1 0 2 2 2 0 HrpJ-like domain TOM20_plant PF06552.12 OAP62125.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Plant specific mitochondrial import receptor subunit TOM20 TPR_12 PF13424.6 OAP62125.1 - 0.22 11.8 1.9 0.92 9.8 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Adaptin_N PF01602.20 OAP62126.1 - 1.5e-86 291.1 0.1 1.9e-86 290.7 0.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 OAP62126.1 - 1.8e-07 31.4 0.1 0.00058 19.9 0.0 2.6 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 OAP62126.1 - 0.0029 17.7 0.2 10 6.7 0.0 4.5 5 0 0 5 5 5 1 HEAT repeat HEAT_EZ PF13513.6 OAP62126.1 - 0.0046 17.4 4.7 0.57 10.7 0.0 4.4 4 1 1 5 5 5 1 HEAT-like repeat UPF0147 PF03685.13 OAP62126.1 - 0.027 14.5 0.1 1.7 8.7 0.0 2.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0147) HEAT_2 PF13646.6 OAP62126.1 - 0.048 14.1 2.3 0.3 11.5 0.1 3.1 3 0 0 3 3 3 0 HEAT repeats IF4E PF01652.18 OAP62129.1 - 1.6e-56 190.5 0.5 1.9e-56 190.3 0.5 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Mpv17_PMP22 PF04117.12 OAP62130.1 - 1.4e-23 82.9 0.1 2.4e-23 82.1 0.1 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family Ribosomal_S5 PF00333.20 OAP62131.1 - 7.8e-27 93.0 1.7 1.1e-26 92.5 0.7 1.8 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 OAP62131.1 - 5.1e-23 80.3 0.0 8.6e-23 79.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain FoP_duplication PF13865.6 OAP62131.1 - 5.7 7.6 10.9 14 6.4 10.9 1.6 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 IKBKB_SDD PF18397.1 OAP62132.1 - 0.061 12.6 0.1 0.074 12.3 0.1 1.1 1 0 0 1 1 1 0 IQBAL scaffold dimerization domain YtxH PF12732.7 OAP62132.1 - 1.2 9.8 4.2 21 5.7 4.2 2.2 1 1 0 1 1 1 0 YtxH-like protein Apolipoprotein PF01442.18 OAP62133.1 - 4.2e-07 30.0 12.6 0.0027 17.6 4.3 2.8 1 1 2 3 3 3 3 Apolipoprotein A1/A4/E domain FAM184 PF15665.5 OAP62133.1 - 0.00051 19.9 17.6 0.11 12.2 0.0 3.5 2 1 1 3 3 3 2 Family with sequence similarity 184, A and B Senescence PF06911.12 OAP62133.1 - 0.024 14.9 7.0 2.4 8.4 0.0 4.6 2 2 1 3 3 3 0 Senescence-associated protein ApoLp-III PF07464.11 OAP62133.1 - 0.027 14.6 2.0 0.027 14.6 2.0 4.6 3 1 1 4 4 4 0 Apolipophorin-III precursor (apoLp-III) XH PF03469.14 OAP62133.1 - 0.028 14.3 9.6 2.4 8.1 0.1 4.1 3 1 1 4 4 4 0 XH domain Peptidase_C39_2 PF13529.6 OAP62133.1 - 0.058 14.0 1.9 2.3 8.7 0.0 3.2 2 2 0 3 3 3 0 Peptidase_C39 like family DUF948 PF06103.11 OAP62133.1 - 0.066 13.5 11.0 1.3 9.3 0.1 5.1 2 2 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Laminin_II PF06009.12 OAP62133.1 - 0.079 13.0 11.9 0.44 10.5 0.3 4.0 2 2 1 4 4 4 0 Laminin Domain II DUF643 PF04867.12 OAP62133.1 - 0.09 13.4 12.8 1.1 10.0 0.8 3.8 3 1 1 4 4 4 0 Protein of unknown function (DUF643) YtxH PF12732.7 OAP62133.1 - 0.11 13.1 24.7 43 4.7 2.5 6.0 2 1 0 2 2 1 0 YtxH-like protein TetR_C_25 PF17933.1 OAP62133.1 - 0.17 12.3 0.2 1.5 9.2 0.0 2.6 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Phasin_2 PF09361.10 OAP62133.1 - 0.17 12.2 10.2 45 4.4 0.5 5.2 2 2 1 3 3 3 0 Phasin protein DUF445 PF04286.12 OAP62133.1 - 0.22 11.3 10.2 0.91 9.3 10.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF445) CarD_CdnL_TRCF PF02559.16 OAP62133.1 - 1.9 9.3 16.4 12 6.7 2.8 4.9 3 1 1 4 4 4 0 CarD-like/TRCF domain Het-C PF07217.11 OAP62133.1 - 4.3 5.7 8.6 0.57 8.7 1.5 2.1 1 1 0 2 2 2 0 Heterokaryon incompatibility protein Het-C 4HB_MCP_1 PF12729.7 OAP62133.1 - 7.3 6.1 8.2 1.9 8.0 1.1 3.2 2 1 2 4 4 4 0 Four helix bundle sensory module for signal transduction GST_N_2 PF13409.6 OAP62134.1 - 2.5e-17 62.9 0.0 6.6e-17 61.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAP62134.1 - 3.2e-12 46.3 0.0 1.1e-11 44.6 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OAP62134.1 - 0.00065 19.8 0.0 0.0013 18.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OAP62134.1 - 0.0033 17.6 0.0 0.01 16.0 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain LIM PF00412.22 OAP62135.1 - 2.3e-14 53.4 13.5 1.2e-08 35.0 4.5 2.3 2 0 0 2 2 2 2 LIM domain TNFR_c6 PF00020.18 OAP62135.1 - 1.7 9.1 10.3 2.3 8.7 0.7 3.6 3 0 0 3 3 3 0 TNFR/NGFR cysteine-rich region NAD_binding_5 PF07994.12 OAP62136.1 - 2.1e-145 484.1 0.1 2.5e-145 483.9 0.1 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 OAP62136.1 - 1.7e-45 153.7 2.5 2.9e-45 153.0 1.0 2.1 2 0 0 2 2 2 1 Myo-inositol-1-phosphate synthase Dehydrin PF00257.19 OAP62137.1 - 0.1 13.1 1.8 0.24 11.9 1.7 1.9 1 1 0 1 1 1 0 Dehydrin SLAC1 PF03595.17 OAP62138.1 - 1e-73 248.4 48.2 1.2e-73 248.2 48.2 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel CPP1-like PF11833.8 OAP62138.1 - 2.2 7.9 4.1 5.8 6.5 4.1 1.8 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like MLTD_N PF06474.12 OAP62139.1 - 0.036 14.2 0.3 0.036 14.2 0.3 2.2 3 0 0 3 3 3 0 MltD lipid attachment motif PIN_4 PF13638.6 OAP62140.1 - 0.0018 18.5 0.0 0.02 15.2 0.0 2.1 2 0 0 2 2 2 1 PIN domain UPF0183 PF03676.14 OAP62141.1 - 3.4e-52 178.1 0.0 7e-35 121.1 0.0 3.0 2 1 0 2 2 2 2 Uncharacterised protein family (UPF0183) Kinesin PF00225.23 OAP62142.1 - 3.8e-109 364.7 0.2 3.8e-109 364.7 0.2 1.8 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 OAP62142.1 - 6.8e-26 91.0 0.1 3.3e-25 88.8 0.0 2.3 2 0 0 2 2 2 1 Microtubule binding Microtub_bind PF13931.6 OAP62142.1 - 8.1e-09 36.0 0.4 8.1e-09 36.0 0.4 4.5 4 1 0 4 4 4 1 Kinesin-associated microtubule-binding Apolipoprotein PF01442.18 OAP62142.1 - 0.0001 22.2 4.2 0.0001 22.2 4.2 3.0 2 1 1 3 3 3 2 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 OAP62142.1 - 0.0015 18.6 0.4 0.0015 18.6 0.4 4.6 4 1 1 5 5 5 2 Baculovirus polyhedron envelope protein, PEP, C terminus Spore_III_AB PF09548.10 OAP62142.1 - 0.015 15.4 8.3 3.5 7.7 7.1 3.8 2 1 1 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) Nas2_N PF18265.1 OAP62142.1 - 2.6 8.1 8.6 1.3 9.0 0.0 4.1 4 0 0 4 4 4 0 Nas2 N_terminal domain DUF4829 PF16111.5 OAP62142.1 - 9.4 7.1 9.6 0.6 10.9 3.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4829) SnoaL_4 PF13577.6 OAP62144.1 - 1.9e-08 34.5 0.5 2.5e-08 34.1 0.5 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 OAP62144.1 - 0.058 13.8 0.3 0.091 13.2 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) Y_phosphatase PF00102.27 OAP62146.1 - 5.1e-49 167.0 0.0 9.3e-23 81.0 0.0 3.1 3 0 0 3 3 3 3 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 OAP62146.1 - 0.0088 16.0 0.0 0.016 15.2 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 OAP62146.1 - 0.092 12.9 0.0 0.27 11.3 0.0 1.8 1 0 0 1 1 1 0 Inositol hexakisphosphate DSPc PF00782.20 OAP62146.1 - 0.13 12.1 0.2 0.38 10.6 0.0 1.8 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain GATA PF00320.27 OAP62147.1 - 2.8e-15 55.6 5.3 6e-15 54.6 5.3 1.6 1 0 0 1 1 1 1 GATA zinc finger zinc_ribbon_9 PF14369.6 OAP62147.1 - 0.41 10.9 1.6 0.88 9.9 1.6 1.5 1 0 0 1 1 1 0 zinc-ribbon Acetyltransf_1 PF00583.25 OAP62148.1 - 0.008 16.4 0.0 0.018 15.3 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 OAP62148.1 - 0.028 14.4 0.0 0.051 13.5 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_9 PF13527.7 OAP62148.1 - 0.16 12.0 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Fungal_trans PF04082.18 OAP62149.1 - 1.3e-23 83.5 0.1 1.8e-23 83.0 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP62149.1 - 3.4e-07 30.3 9.0 5.3e-07 29.7 9.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Actin PF00022.19 OAP62150.1 - 8.6e-113 377.0 0.0 6e-112 374.2 0.0 1.8 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 OAP62150.1 - 0.06 12.1 0.0 0.22 10.3 0.0 1.9 1 1 0 1 1 1 0 MreB/Mbl protein Pap_E4 PF02711.14 OAP62151.1 - 0.0087 17.0 1.1 0.0087 17.0 1.1 2.7 3 0 0 3 3 3 1 E4 protein Trp_oprn_chp PF09534.10 OAP62151.1 - 0.052 13.3 1.5 1.6 8.5 0.0 2.4 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) SQS_PSY PF00494.19 OAP62152.1 - 1.6e-36 126.2 0.0 2.3e-36 125.6 0.0 1.3 1 0 0 1 1 1 1 Squalene/phytoene synthase SabA_adhesion PF18304.1 OAP62152.1 - 0.011 15.0 0.0 0.02 14.1 0.0 1.4 1 0 0 1 1 1 0 SabA N-terminal extracellular adhesion domain Peroxin-22 PF12827.7 OAP62152.1 - 0.028 14.4 0.0 0.23 11.4 0.0 2.3 2 0 0 2 2 2 0 Peroxisomal biogenesis protein family IL6Ra-bind PF09240.10 OAP62152.1 - 0.85 10.1 3.1 0.94 9.9 0.1 2.5 3 0 0 3 3 3 0 Interleukin-6 receptor alpha chain, binding DnaJ-X PF14308.6 OAP62153.1 - 1.7e-78 262.9 3.2 1.7e-78 262.9 3.2 3.3 3 1 1 4 4 4 1 X-domain of DnaJ-containing DnaJ PF00226.31 OAP62153.1 - 9.7e-25 86.5 0.4 3.1e-24 84.9 0.4 2.0 1 0 0 1 1 1 1 DnaJ domain Homeodomain PF00046.29 OAP62153.1 - 0.029 14.2 1.0 0.07 13.0 1.0 1.6 1 0 0 1 1 1 0 Homeodomain OrfB_IS605 PF01385.19 OAP62153.1 - 2.2 8.5 10.5 0.041 14.1 2.4 2.3 3 0 0 3 3 3 0 Probable transposase IMS PF00817.20 OAP62155.1 - 1.3e-42 145.3 1.1 2.3e-42 144.5 0.4 1.8 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.8 OAP62155.1 - 7.6e-15 55.6 0.3 1.8e-14 54.4 0.3 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 OAP62155.1 - 6.1e-05 23.1 0.0 0.00018 21.6 0.0 1.9 1 0 0 1 1 1 1 IMS family HHH motif Vps36-NZF-N PF16988.5 OAP62155.1 - 0.094 12.1 1.0 1.2 8.6 0.1 2.4 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain EamA PF00892.20 OAP62156.1 - 1.2e-10 41.7 24.6 9.2e-06 25.9 3.8 2.6 2 0 0 2 2 2 2 EamA-like transporter family CSG2 PF16965.5 OAP62156.1 - 0.025 13.5 17.7 0.78 8.6 17.5 3.0 1 1 0 1 1 1 0 Ceramide synthase regulator FAM176 PF14851.6 OAP62156.1 - 0.76 9.4 3.5 0.51 10.0 0.2 2.1 2 0 0 2 2 2 0 FAM176 family TMEM234 PF10639.9 OAP62156.1 - 5.4 7.1 11.7 3.2 7.8 1.5 2.7 3 0 0 3 3 3 0 Putative transmembrane family 234 FAD_binding_4 PF01565.23 OAP62157.1 - 4.4e-16 58.9 0.1 8.2e-16 58.0 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 OAP62157.1 - 0.00044 20.3 0.6 0.00092 19.3 0.1 1.7 2 0 0 2 2 2 1 Berberine and berberine like GMC_oxred_N PF00732.19 OAP62158.1 - 1e-58 199.1 0.0 1.3e-58 198.7 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAP62158.1 - 1.1e-33 116.7 0.0 1.9e-33 116.0 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 OAP62158.1 - 8e-05 21.9 0.0 0.00013 21.2 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 OAP62158.1 - 9.5e-05 22.6 0.1 0.00045 20.4 0.0 2.2 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 OAP62158.1 - 0.00027 20.2 0.1 0.013 14.6 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.6 OAP62158.1 - 0.0005 19.4 1.4 0.34 10.1 0.0 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAP62158.1 - 0.0019 17.8 0.3 0.059 12.9 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 OAP62158.1 - 0.0023 17.2 0.0 0.0042 16.3 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 OAP62158.1 - 0.015 14.6 0.1 2.4 7.3 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Aldo_ket_red PF00248.21 OAP62159.1 - 3.4e-51 174.2 0.0 3.9e-51 174.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family NIBRIN_BRCT_II PF16508.5 OAP62160.1 - 2e-32 112.0 0.0 4.9e-32 110.7 0.0 1.7 1 0 0 1 1 1 1 Second BRCT domain on Nijmegen syndrome breakage protein FHA PF00498.26 OAP62160.1 - 2.5e-10 40.6 0.6 8.6e-10 38.8 0.2 2.1 2 0 0 2 2 2 1 FHA domain RTT107_BRCT_5 PF16770.5 OAP62160.1 - 0.0073 16.2 0.1 0.028 14.3 0.1 2.0 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain OAF PF14941.6 OAP62160.1 - 0.1 12.1 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator, Out at first RPEL PF02755.15 OAP62161.1 - 1.8e-27 94.2 20.3 4.1e-09 35.8 0.6 3.5 3 0 0 3 3 3 3 RPEL repeat Rotamase_3 PF13616.6 OAP62161.1 - 0.11 13.0 2.6 0.5 10.9 0.7 2.0 1 1 1 2 2 2 0 PPIC-type PPIASE domain Translin PF01997.16 OAP62162.1 - 3.7e-63 213.2 0.1 4.2e-63 213.0 0.1 1.0 1 0 0 1 1 1 1 Translin family Leu_leader PF08054.11 OAP62162.1 - 1 9.0 2.7 1.7 8.3 0.4 2.3 3 0 0 3 3 3 0 Leucine operon leader peptide Mannosyl_trans PF05007.13 OAP62163.1 - 2.6e-74 250.4 16.9 3.8e-74 249.8 16.9 1.2 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.13 OAP62163.1 - 3.3e-09 36.3 9.2 3.3e-09 36.3 9.2 2.2 2 0 0 2 2 2 1 GPI transamidase subunit PIG-U Bac_rhodopsin PF01036.18 OAP62166.1 - 2.3e-53 181.1 17.7 2.8e-53 180.8 17.7 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein Heliorhodopsin PF18761.1 OAP62166.1 - 0.0013 18.1 10.0 0.002 17.5 9.6 1.6 1 1 0 1 1 1 1 Heliorhodopsin MerC PF03203.14 OAP62166.1 - 0.0071 16.8 12.2 0.0073 16.8 6.3 2.3 2 0 0 2 2 2 1 MerC mercury resistance protein LMBR1 PF04791.16 OAP62166.1 - 0.038 12.9 0.2 0.038 12.9 0.2 1.7 1 1 0 1 1 1 0 LMBR1-like membrane protein DUF1772 PF08592.11 OAP62166.1 - 0.36 11.1 14.4 1.7 9.0 3.9 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) Phage_holin_3_6 PF07332.11 OAP62166.1 - 1.3 9.1 14.6 2.2 8.4 8.8 2.5 2 1 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III tRNA-synt_1 PF00133.22 OAP62167.1 - 3e-147 491.5 0.0 3.9e-147 491.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 OAP62167.1 - 4e-20 71.9 0.0 2.5e-12 46.3 0.0 3.3 3 0 0 3 3 3 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 OAP62167.1 - 6.3e-20 71.7 0.2 1.2e-19 70.8 0.2 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 OAP62167.1 - 0.005 16.2 0.0 1 8.7 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain zf-FPG_IleRS PF06827.14 OAP62167.1 - 0.15 12.0 4.8 0.54 10.2 4.8 2.0 1 1 0 1 1 1 0 Zinc finger found in FPG and IleRS tRNA-synt_1_2 PF13603.6 OAP62167.1 - 0.17 11.4 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 Leucyl-tRNA synthetase, Domain 2 HET PF06985.11 OAP62168.1 - 1.5e-05 25.4 0.2 0.0037 17.6 0.0 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) DUF872 PF05915.12 OAP62170.1 - 0.11 12.6 0.3 10 6.3 0.0 2.7 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) Rhodanese PF00581.20 OAP62171.1 - 1.5e-13 51.2 0.0 1.6e-07 31.8 0.0 2.3 2 0 0 2 2 2 2 Rhodanese-like domain Peptidase_M24 PF00557.24 OAP62172.1 - 1.1e-49 168.9 0.0 1.4e-49 168.6 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 OAP62172.1 - 1.4e-18 66.9 8.2 3.2e-18 65.7 8.2 1.6 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 OAP62172.1 - 7.9e-05 22.7 5.3 0.00023 21.2 5.3 1.8 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.16 OAP62172.1 - 0.07 13.0 4.7 0.18 11.7 4.7 1.8 1 0 0 1 1 1 0 HIT zinc finger ZZ PF00569.17 OAP62173.1 - 1.1e-11 44.3 6.5 2e-11 43.5 6.5 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type EF-hand_1 PF00036.32 OAP62173.1 - 2.5e-10 39.1 5.8 0.0002 20.7 0.5 3.1 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 OAP62173.1 - 7.8e-10 39.1 2.3 0.00092 19.6 0.7 3.6 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 OAP62173.1 - 1.2e-08 34.2 3.6 0.00053 19.7 0.4 3.0 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 OAP62173.1 - 0.0032 16.9 5.9 0.72 9.5 0.1 3.5 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 OAP62173.1 - 0.026 14.3 6.4 0.24 11.3 0.2 3.4 4 0 0 4 4 4 0 EF-hand domain pair DUF4519 PF15012.6 OAP62173.1 - 0.24 11.6 1.3 0.54 10.5 1.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) zf-B_box PF00643.24 OAP62173.1 - 0.27 11.4 6.8 0.44 10.7 6.8 1.3 1 0 0 1 1 1 0 B-box zinc finger C1_2 PF03107.16 OAP62173.1 - 2.1 8.7 9.7 3.8 7.9 9.7 1.4 1 0 0 1 1 1 0 C1 domain WD40 PF00400.32 OAP62175.1 - 1.7e-14 53.9 14.4 7.9e-05 23.4 0.0 6.6 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAP62175.1 - 3.5e-07 30.4 0.0 0.28 11.5 0.0 4.7 3 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.12 OAP62175.1 - 0.17 9.9 0.0 3.3 5.6 0.0 2.6 3 0 0 3 3 3 0 IKI3 family MutS_V PF00488.21 OAP62176.1 - 6.7e-63 212.1 0.2 1.6e-62 210.9 0.2 1.6 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.18 OAP62176.1 - 6.1e-33 114.7 2.2 1.5e-32 113.4 2.2 1.7 1 0 0 1 1 1 1 MutS domain III MutS_II PF05188.17 OAP62176.1 - 3.9e-12 46.6 0.1 1.1e-11 45.1 0.1 1.8 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 OAP62176.1 - 3.5e-08 33.7 1.4 9.2e-08 32.3 1.4 1.8 1 0 0 1 1 1 1 MutS family domain IV AAA_27 PF13514.6 OAP62176.1 - 0.044 13.4 0.0 0.13 11.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain RNA_pol_3_Rpc31 PF11705.8 OAP62176.1 - 0.048 13.9 8.3 0.1 12.8 8.3 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DUF3213 PF11491.8 OAP62176.1 - 0.056 13.6 0.1 0.17 12.1 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) Cwf_Cwc_15 PF04889.12 OAP62176.1 - 2.6 7.7 9.1 5 6.8 9.1 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 OAP62176.1 - 9 5.5 13.0 16 4.7 13.0 1.3 1 0 0 1 1 1 0 NOA36 protein WD40 PF00400.32 OAP62177.1 - 7.5e-65 213.3 32.1 2.9e-12 46.9 0.6 9.5 9 0 0 9 9 9 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAP62177.1 - 1.6e-24 86.0 6.2 2e-05 24.8 0.1 6.8 3 2 5 8 8 7 7 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OAP62177.1 - 1.7e-13 50.3 4.4 0.014 14.4 1.7 6.5 3 3 4 7 7 7 4 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 OAP62177.1 - 2.6e-06 26.4 9.3 0.59 8.7 1.6 5.8 4 2 1 6 6 6 2 Nucleoporin Nup120/160 eIF2A PF08662.11 OAP62177.1 - 6.2e-06 26.2 0.0 0.056 13.3 0.0 2.8 2 2 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A NLE PF08154.12 OAP62177.1 - 0.00012 22.5 0.0 0.00025 21.5 0.0 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain IKI3 PF04762.12 OAP62177.1 - 0.00033 18.8 0.1 0.76 7.7 0.0 3.2 2 1 1 3 3 3 3 IKI3 family Nbas_N PF15492.6 OAP62177.1 - 0.00035 20.0 0.9 5.2 6.3 0.1 4.0 4 1 1 5 5 5 2 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.12 OAP62177.1 - 0.02 14.8 3.0 1.4 8.9 0.0 3.7 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat FAD_binding_9 PF08021.11 OAP62177.1 - 0.053 13.7 0.0 0.18 12.0 0.0 1.8 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain Nucleoporin_N PF08801.11 OAP62177.1 - 0.085 11.6 2.7 1.1 8.0 2.7 2.9 1 1 0 1 1 1 0 Nup133 N terminal like Proteasome_A_N PF10584.9 OAP62177.1 - 0.18 11.5 0.5 20 5.0 0.0 3.3 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature Cytochrom_C1 PF02167.15 OAP62178.1 - 1.7e-93 312.4 0.0 2.1e-93 312.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 OAP62178.1 - 0.0076 16.6 0.0 0.017 15.4 0.0 1.7 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 OAP62178.1 - 0.023 15.8 0.0 0.11 13.6 0.0 2.2 2 0 0 2 2 2 0 Cytochrome c RSN1_7TM PF02714.15 OAP62179.1 - 8.5e-81 271.3 18.6 8.5e-81 271.3 18.6 2.0 3 0 0 3 3 3 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 OAP62179.1 - 1.4e-41 142.6 0.0 2.1e-41 142.1 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 OAP62179.1 - 3.8e-37 127.5 1.2 3.8e-37 127.5 1.2 2.6 2 1 0 2 2 2 1 Late exocytosis, associated with Golgi transport Phage_holin_4_1 PF05105.12 OAP62179.1 - 0.081 13.1 0.8 0.31 11.2 0.8 2.0 1 0 0 1 1 1 0 Bacteriophage holin family CcmD PF04995.14 OAP62179.1 - 4.2 7.5 5.2 2.2 8.4 1.5 2.7 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) F-box-like PF12937.7 OAP62180.1 - 1.2e-09 37.9 0.8 5.1e-06 26.3 0.2 2.5 2 0 0 2 2 2 2 F-box-like F-box PF00646.33 OAP62180.1 - 4.2e-09 36.1 0.2 0.0009 19.1 0.1 2.7 2 0 0 2 2 2 2 F-box domain Aminotran_3 PF00202.21 OAP62181.1 - 8.3e-34 116.9 0.0 2.4e-21 75.9 0.0 4.5 4 1 0 4 4 4 2 Aminotransferase class-III AAA_26 PF13500.6 OAP62181.1 - 1.4e-21 77.2 0.0 2.4e-21 76.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 OAP62181.1 - 0.12 12.4 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain PsaL PF02605.15 OAP62182.1 - 0.052 13.2 0.2 1 9.0 0.0 2.3 2 0 0 2 2 2 0 Photosystem I reaction centre subunit XI UBA_6 PF18039.1 OAP62182.1 - 0.064 13.2 0.2 0.26 11.3 0.1 2.1 2 0 0 2 2 2 0 UBA-like domain Aminotran_1_2 PF00155.21 OAP62184.1 - 8e-44 150.3 0.0 9.2e-44 150.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 OAP62184.1 - 9.3e-09 34.3 0.0 1.4e-08 33.7 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_3 PF00202.21 OAP62184.1 - 0.0056 15.4 0.0 0.0078 14.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 OAP62184.1 - 0.022 14.1 0.0 0.032 13.5 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase Sulfotransfer_4 PF17784.1 OAP62185.1 - 2.2e-58 197.6 0.1 2.5e-58 197.4 0.1 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OAP62185.1 - 0.00055 20.4 1.5 0.4 11.0 0.1 2.8 1 1 1 2 2 2 2 Sulfotransferase family IL22 PF14565.6 OAP62186.1 - 0.082 13.2 0.1 12 6.1 0.0 2.2 2 0 0 2 2 2 0 Interleukin 22 IL-10-related T-cell-derived-inducible factor VitD-bind_III PF09164.10 OAP62186.1 - 0.74 9.8 3.4 2.2 8.3 3.4 1.7 1 0 0 1 1 1 0 Vitamin D binding protein, domain III bZIP_1 PF00170.21 OAP62186.1 - 3.8 7.7 11.1 9 6.5 7.2 2.3 2 0 0 2 2 2 0 bZIP transcription factor adh_short PF00106.25 OAP62187.1 - 5.2e-24 84.8 0.0 1.2e-21 77.0 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAP62187.1 - 4.3e-16 59.2 0.0 2.2e-14 53.6 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP62187.1 - 2e-07 31.1 0.1 3.2e-07 30.4 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAP62187.1 - 1.3e-05 24.8 0.0 1.9e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 OAP62187.1 - 0.0044 16.2 0.0 0.02 14.0 0.0 1.8 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Fungal_trans_2 PF11951.8 OAP62188.1 - 4.1e-20 72.0 3.1 3.1e-13 49.3 0.3 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP62188.1 - 1.7e-09 37.7 7.7 2.5e-09 37.1 7.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ecm29 PF13001.7 OAP62189.1 - 1.5e-127 426.3 1.7 1.5e-127 426.3 1.7 2.9 3 0 0 3 3 3 1 Proteasome stabiliser RIX1 PF08167.12 OAP62189.1 - 0.0042 16.8 4.0 0.065 13.0 0.0 3.9 4 0 0 4 4 4 1 rRNA processing/ribosome biogenesis Vac14_Fab1_bd PF12755.7 OAP62189.1 - 0.01 16.4 0.3 3.9 8.1 0.1 4.3 4 1 0 4 4 4 0 Vacuolar 14 Fab1-binding region HEAT PF02985.22 OAP62189.1 - 0.081 13.2 9.5 23 5.6 0.0 7.9 9 0 0 9 9 9 0 HEAT repeat HEAT_EZ PF13513.6 OAP62189.1 - 0.2 12.2 11.0 28 5.3 0.0 7.3 9 0 0 9 9 9 0 HEAT-like repeat Ribosomal_S28e PF01200.18 OAP62190.1 - 4e-31 106.8 1.8 4.5e-31 106.6 1.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e HisG PF01634.18 OAP62191.1 - 4.6e-59 198.9 0.1 6.5e-59 198.5 0.1 1.2 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 OAP62191.1 - 2.2e-28 98.2 1.2 3.1e-28 97.7 0.3 1.7 2 0 0 2 2 2 1 HisG, C-terminal domain NMT1 PF09084.11 OAP62191.1 - 0.0032 17.4 0.1 0.0052 16.8 0.1 1.3 1 0 0 1 1 1 1 NMT1/THI5 like DUF3262 PF11660.8 OAP62192.1 - 0.011 16.1 0.1 0.27 11.7 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3262) DUF2721 PF11026.8 OAP62192.1 - 0.019 14.9 0.1 0.026 14.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) PufQ PF05398.11 OAP62192.1 - 0.34 11.1 2.0 1.2 9.3 1.5 2.0 1 1 1 2 2 2 0 PufQ cytochrome subunit Fcf1 PF04900.12 OAP62193.1 - 1.8e-38 130.9 0.3 2.9e-38 130.3 0.3 1.3 1 0 0 1 1 1 1 Fcf1 PIN_9 PF18477.1 OAP62193.1 - 1.2e-12 48.2 0.1 2.2e-12 47.3 0.1 1.4 1 0 0 1 1 1 1 PIN like domain DUF4706 PF15797.5 OAP62193.1 - 0.062 13.8 0.3 0.16 12.5 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4706) DUF2613 PF11021.8 OAP62194.1 - 4.1 7.6 7.5 3.5 7.8 4.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) ATP11 PF06644.11 OAP62195.1 - 4.4e-99 331.7 0.0 5e-99 331.5 0.0 1.0 1 0 0 1 1 1 1 ATP11 protein Hydrolase_4 PF12146.8 OAP62196.1 - 7.3e-17 61.4 0.0 1.3e-10 41.0 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OAP62196.1 - 4e-13 49.6 0.1 1e-07 31.9 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold AXE1 PF05448.12 OAP62196.1 - 7.6e-11 41.2 0.0 2e-06 26.7 0.0 3.0 1 1 1 2 2 2 2 Acetyl xylan esterase (AXE1) BAAT_C PF08840.11 OAP62196.1 - 2e-07 31.2 0.0 0.0011 18.9 0.0 2.2 1 1 1 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_6 PF12697.7 OAP62196.1 - 2.8e-06 28.1 0.0 2e-05 25.3 0.0 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family FSH1 PF03959.13 OAP62196.1 - 6e-05 22.8 0.0 9.4e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_S15 PF02129.18 OAP62196.1 - 0.00017 21.3 0.0 0.2 11.2 0.0 2.4 2 0 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 OAP62196.1 - 0.00043 19.8 0.0 0.00074 19.1 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family LIDHydrolase PF10230.9 OAP62196.1 - 0.00079 19.1 0.0 0.069 12.7 0.1 2.1 1 1 1 2 2 2 1 Lipid-droplet associated hydrolase Abhydrolase_3 PF07859.13 OAP62196.1 - 0.00087 19.2 0.0 0.0018 18.2 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.18 OAP62196.1 - 0.001 18.7 0.0 0.012 15.2 0.0 2.1 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_4 PF08386.10 OAP62196.1 - 0.025 14.7 0.0 0.047 13.8 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein Acyl_transf_2 PF02273.15 OAP62196.1 - 0.032 13.5 0.0 0.078 12.2 0.0 1.5 2 0 0 2 2 2 0 Acyl transferase Lipase_3 PF01764.25 OAP62196.1 - 0.04 13.8 0.0 0.14 12.0 0.0 1.8 1 1 0 2 2 2 0 Lipase (class 3) Abhydrolase_2 PF02230.16 OAP62196.1 - 0.052 13.3 0.0 1.4 8.7 0.0 2.2 1 1 1 2 2 2 0 Phospholipase/Carboxylesterase DUF818 PF05677.12 OAP62196.1 - 0.076 11.9 0.0 0.094 11.7 0.0 1.1 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) UPF0227 PF05728.12 OAP62196.1 - 0.08 12.9 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Proteasome PF00227.26 OAP62197.1 - 3.2e-46 157.2 0.4 4.6e-46 156.7 0.4 1.2 1 0 0 1 1 1 1 Proteasome subunit Cyclin PF08613.11 OAP62197.1 - 1.7e-39 135.7 0.1 4.2e-24 85.7 0.1 2.4 2 0 0 2 2 2 2 Cyclin SNF2_N PF00176.23 OAP62198.1 - 9.6e-53 179.1 0.4 3.1e-51 174.1 0.0 2.6 2 1 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OAP62198.1 - 6.2e-18 65.2 0.0 7.7e-17 61.6 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAP62198.1 - 5.2e-06 26.6 0.0 2.6e-05 24.3 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.25 OAP62198.1 - 3.5e-05 23.6 6.4 3.5e-05 23.6 6.4 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OAP62198.1 - 0.0016 18.3 7.2 0.0016 18.3 7.2 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) AAA_34 PF13872.6 OAP62198.1 - 0.0044 15.9 0.2 0.01 14.7 0.0 1.7 2 0 0 2 2 2 1 P-loop containing NTP hydrolase pore-1 DEAD PF00270.29 OAP62198.1 - 0.0058 16.4 0.0 0.014 15.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 OAP62198.1 - 0.01 15.1 0.0 0.018 14.2 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Zn_Tnp_IS91 PF14319.6 OAP62198.1 - 0.23 11.5 14.5 0.15 12.1 2.6 2.6 2 0 0 2 2 2 0 Transposase zinc-binding domain DUF4196 PF13846.6 OAP62198.1 - 0.54 10.5 10.3 0.036 14.3 3.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4196) LRR_4 PF12799.7 OAP62199.1 - 0.0098 16.3 6.5 9.5 6.8 0.6 5.0 3 1 3 6 6 6 1 Leucine Rich repeats (2 copies) Rrn6 PF10214.9 OAP62199.1 - 0.028 12.9 0.6 0.039 12.4 0.1 1.3 1 1 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor CFAP91 PF14738.6 OAP62199.1 - 0.056 13.5 6.8 0.18 11.8 6.8 1.8 1 0 0 1 1 1 0 Cilia- and flagella-associated protein 91 INCENP_N PF12178.8 OAP62199.1 - 0.069 13.2 0.0 0.32 11.0 0.0 2.2 2 0 0 2 2 2 0 Chromosome passenger complex (CPC) protein INCENP N terminal FYVE PF01363.21 OAP62199.1 - 0.17 12.1 0.7 0.6 10.3 0.7 1.9 1 1 0 1 1 1 0 FYVE zinc finger LRR_8 PF13855.6 OAP62199.1 - 3.2 7.6 5.7 7.3 6.4 2.4 3.3 2 1 1 3 3 3 0 Leucine rich repeat MutS_V PF00488.21 OAP62200.1 - 3.3e-73 245.7 0.4 6.9e-73 244.7 0.2 1.7 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.18 OAP62200.1 - 1.3e-37 129.8 0.5 2.9e-37 128.8 0.5 1.6 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 OAP62200.1 - 3e-29 101.5 0.3 7.2e-29 100.3 0.0 1.8 2 0 0 2 2 2 1 MutS domain I MutS_II PF05188.17 OAP62200.1 - 4.3e-09 36.8 0.0 1.2e-08 35.4 0.0 1.8 1 0 0 1 1 1 1 MutS domain II DUF4911 PF16256.5 OAP62200.1 - 0.0041 17.1 0.0 0.015 15.3 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4911) MutS_IV PF05190.18 OAP62200.1 - 0.011 16.1 0.0 0.026 14.9 0.0 1.7 1 0 0 1 1 1 0 MutS family domain IV FAD_binding_3 PF01494.19 OAP62201.1 - 4.5e-23 82.1 0.0 1.8e-22 80.1 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAP62201.1 - 4.7e-05 23.1 0.1 0.022 14.3 0.0 2.4 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 OAP62201.1 - 0.0067 16.4 0.0 0.016 15.2 0.0 1.7 1 0 0 1 1 1 1 FAD-NAD(P)-binding Sacchrp_dh_NADP PF03435.18 OAP62201.1 - 0.036 14.3 0.0 0.097 12.9 0.0 1.7 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Pyr_redox_2 PF07992.14 OAP62201.1 - 0.074 12.3 0.0 6 6.0 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 OAP62201.1 - 0.11 11.5 0.0 0.58 9.2 0.0 1.9 2 0 0 2 2 2 0 Squalene epoxidase BAF PF02961.14 OAP62202.1 - 0.079 13.4 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 Barrier to autointegration factor ubiquitin PF00240.23 OAP62203.1 - 0.00029 20.5 0.0 0.00068 19.3 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin family Pkinase PF00069.25 OAP62204.1 - 2.7e-64 217.1 0.0 3.7e-64 216.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP62204.1 - 1.2e-36 126.3 0.0 1.5e-36 126.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAP62204.1 - 0.0017 17.8 0.0 0.0025 17.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OAP62204.1 - 0.052 12.3 0.0 0.14 10.9 0.0 1.6 2 0 0 2 2 2 0 Fungal protein kinase APH PF01636.23 OAP62204.1 - 0.072 13.0 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family IGR PF09597.10 OAP62205.1 - 1.9e-26 91.9 1.3 3.8e-26 91.0 1.3 1.5 1 0 0 1 1 1 1 IGR protein motif Cloacin PF03515.14 OAP62205.1 - 0.12 12.1 0.1 0.19 11.4 0.1 1.3 1 0 0 1 1 1 0 Colicin-like bacteriocin tRNase domain Kinesin PF00225.23 OAP62206.1 - 1e-94 317.2 0.0 2.4e-94 316.0 0.0 1.6 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 OAP62206.1 - 1.1e-22 80.6 0.0 6.3e-22 78.1 0.0 2.1 2 0 0 2 2 2 1 Microtubule binding DUF4407 PF14362.6 OAP62206.1 - 0.037 13.4 12.4 0.087 12.2 2.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Spc7 PF08317.11 OAP62206.1 - 0.3 9.9 15.3 1.7 7.5 5.5 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein UPF0242 PF06785.11 OAP62206.1 - 0.35 11.0 9.6 1 9.4 0.2 2.8 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus FapA PF03961.13 OAP62206.1 - 2 7.0 7.3 1.9 7.0 1.8 2.2 2 0 0 2 2 2 0 Flagellar Assembly Protein A RHS PF03527.14 OAP62207.1 - 0.1 12.4 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 RHS protein AMP-binding PF00501.28 OAP62208.1 - 6.6e-58 196.3 0.0 9.3e-58 195.8 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAP62208.1 - 1.5e-09 38.7 0.1 2.7e-09 37.9 0.1 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain YL1_C PF08265.11 OAP62208.1 - 0.095 12.5 0.2 0.23 11.3 0.2 1.6 1 0 0 1 1 1 0 YL1 nuclear protein C-terminal domain Eisosome1 PF12757.7 OAP62209.1 - 9.6e-38 129.3 15.2 9.6e-38 129.3 15.2 5.8 4 2 1 5 5 5 1 Eisosome protein 1 TSP9 PF11493.8 OAP62209.1 - 0.069 13.8 0.4 0.56 10.9 0.4 2.7 1 0 0 1 1 1 0 Thylakoid soluble phosphoprotein TSP9 Y_phosphatase3 PF13350.6 OAP62210.1 - 6.1e-40 137.6 0.0 1.3e-39 136.6 0.0 1.5 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 OAP62210.1 - 2.6e-06 27.1 0.0 8e-06 25.5 0.0 1.7 2 0 0 2 2 2 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 OAP62210.1 - 0.014 15.0 0.0 0.022 14.3 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Frag1 PF10277.9 OAP62211.1 - 2.1e-46 158.2 19.0 2.5e-46 158.0 19.0 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family EMP70 PF02990.16 OAP62211.1 - 0.00029 19.6 2.0 0.00045 19.0 2.0 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 SPC25 PF06703.11 OAP62211.1 - 0.059 13.2 0.4 0.11 12.3 0.2 1.6 1 1 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) 60KD_IMP PF02096.20 OAP62211.1 - 0.088 12.7 0.3 0.13 12.1 0.3 1.4 1 1 0 1 1 1 0 60Kd inner membrane protein DUF973 PF06157.11 OAP62211.1 - 0.58 9.2 4.4 1 8.3 4.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF973) DUF2964 PF11177.8 OAP62211.1 - 5.7 7.2 7.1 1.4 9.1 0.6 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2964) DUF3533 PF12051.8 OAP62212.1 - 9.4e-71 238.7 6.4 1.1e-70 238.5 6.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) DnaJ PF00226.31 OAP62213.1 - 6.8e-21 74.2 2.8 1.5e-20 73.1 2.8 1.6 1 0 0 1 1 1 1 DnaJ domain DUF1269 PF06897.12 OAP62213.1 - 0.0023 18.2 0.9 0.004 17.4 0.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1269) SARAF PF06682.12 OAP62213.1 - 0.0093 15.6 0.4 0.12 12.0 0.4 2.0 1 1 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis Gly-zipper_Omp PF13488.6 OAP62213.1 - 0.0098 15.9 6.4 0.015 15.3 6.4 1.3 1 0 0 1 1 1 1 Glycine zipper DUF456 PF04306.13 OAP62213.1 - 0.011 16.1 0.3 0.015 15.6 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF456) Gly-zipper_YMGG PF13441.6 OAP62213.1 - 0.035 13.8 7.8 0.056 13.2 7.8 1.3 1 0 0 1 1 1 0 YMGG-like Gly-zipper PT-VENN PF04829.13 OAP62213.1 - 0.81 9.8 5.4 0.4 10.8 2.0 1.9 2 0 0 2 2 2 0 Pre-toxin domain with VENN motif Rick_17kDa_Anti PF05433.15 OAP62213.1 - 1.5 8.7 13.2 2.7 7.9 13.2 1.3 1 0 0 1 1 1 0 Glycine zipper 2TM domain Bacteriocin_IIc PF10439.9 OAP62213.1 - 2.7 8.2 8.6 5.4 7.2 8.6 1.5 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide PRA1 PF03208.19 OAP62216.1 - 2.2e-36 124.6 0.4 2.7e-36 124.3 0.4 1.1 1 0 0 1 1 1 1 PRA1 family protein DnaJ PF00226.31 OAP62217.1 - 2e-07 31.0 0.0 4.9e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain Fungal_trans_2 PF11951.8 OAP62218.1 - 0.015 14.1 0.1 0.023 13.5 0.1 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain Cornichon PF03311.14 OAP62219.1 - 9.6e-42 142.2 5.7 1.1e-41 141.9 5.7 1.0 1 0 0 1 1 1 1 Cornichon protein WD40 PF00400.32 OAP62220.1 - 6.1e-28 96.5 6.4 1.7e-06 28.6 0.0 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAP62220.1 - 2.1e-13 50.4 0.0 0.0068 16.7 0.0 4.9 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 OAP62220.1 - 5.7e-06 26.1 0.0 1.5e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 PQQ-like domain Cytochrom_D1 PF02239.16 OAP62220.1 - 0.011 14.3 0.0 0.021 13.3 0.0 1.4 1 0 0 1 1 1 0 Cytochrome D1 heme domain Nup160 PF11715.8 OAP62220.1 - 0.12 11.0 0.0 0.53 8.9 0.0 1.8 1 1 1 2 2 2 0 Nucleoporin Nup120/160 DUF1513 PF07433.11 OAP62220.1 - 0.13 11.3 0.2 1.8 7.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1513) Sod_Fe_C PF02777.18 OAP62221.1 - 8.6e-18 64.4 0.0 8.2e-08 32.3 0.2 2.5 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain OAM_alpha PF16552.5 OAP62221.1 - 0.18 11.7 0.0 0.36 10.7 0.0 1.5 1 0 0 1 1 1 0 D-ornithine 4,5-aminomutase alpha-subunit Lustrin_cystein PF14625.6 OAP62222.1 - 3.1 8.2 17.2 3.5 8.1 5.2 2.9 2 0 0 2 2 2 0 Lustrin, cysteine-rich repeated domain CS PF04969.16 OAP62223.1 - 1.6e-17 64.3 0.1 3.7e-17 63.1 0.1 1.7 1 0 0 1 1 1 1 CS domain DUF4404 PF14357.6 OAP62223.1 - 0.26 12.0 1.4 0.68 10.6 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) Melibiase_2 PF16499.5 OAP62224.1 - 2.4e-52 177.9 2.0 9.4e-37 126.7 0.7 2.2 2 0 0 2 2 2 2 Alpha galactosidase A Melibiase_C PF17801.1 OAP62224.1 - 8.3e-11 41.8 1.5 1e-08 35.1 1.3 2.6 2 0 0 2 2 2 2 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 OAP62224.1 - 0.002 17.2 0.0 0.0033 16.5 0.0 1.3 1 0 0 1 1 1 1 Melibiase UbiA PF01040.18 OAP62225.1 - 6.5e-57 192.7 12.9 1e-56 192.1 12.9 1.3 1 0 0 1 1 1 1 UbiA prenyltransferase family Med8 PF10232.9 OAP62226.1 - 3.6e-44 151.1 2.0 4e-44 150.9 2.0 1.0 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 Astro_capsid_p PF12226.8 OAP62226.1 - 0.015 14.5 8.5 0.015 14.5 8.5 1.7 2 0 0 2 2 2 0 Turkey astrovirus capsid protein Acyl-CoA_dh_1 PF00441.24 OAP62228.1 - 6.2e-33 114.1 0.2 1.2e-32 113.2 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.28 OAP62228.1 - 9.1e-21 73.8 0.0 2.9e-20 72.2 0.0 1.9 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.19 OAP62228.1 - 2.5e-19 69.2 0.2 4.3e-19 68.5 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 OAP62228.1 - 4e-10 40.3 0.0 1e-09 39.0 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 OAP62228.1 - 2.6e-05 24.5 0.0 7.4e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain PIG-S PF10510.9 OAP62229.1 - 5.7e-139 464.3 0.0 7.4e-139 463.9 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein Amidase PF01425.21 OAP62229.1 - 2.8e-12 46.4 0.1 5.6e-12 45.4 0.1 1.5 1 1 0 1 1 1 1 Amidase DUF4128 PF13554.6 OAP62229.1 - 0.0051 16.9 0.1 0.038 14.0 0.0 2.2 2 0 0 2 2 2 1 Bacteriophage related domain of unknown function HU-CCDC81_euk_2 PF18289.1 OAP62229.1 - 0.12 12.5 0.0 0.34 11.1 0.0 1.8 1 0 0 1 1 1 0 CCDC81 eukaryotic HU domain 2 Adhesin_P1 PF03257.13 OAP62229.1 - 1.9 9.0 0.0 1.9 9.0 0.0 3.5 5 0 0 5 5 5 0 Mycoplasma adhesin P1 Polyketide_cyc PF03364.20 OAP62230.1 - 2.3e-22 79.6 0.0 2.7e-22 79.4 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 OAP62230.1 - 2.1e-06 28.1 0.1 2.6e-06 27.8 0.1 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport DUF1687 PF07955.11 OAP62230.1 - 0.022 15.2 0.4 0.031 14.7 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1687) Insulin_TMD PF17870.1 OAP62231.1 - 0.18 11.9 0.1 0.36 10.9 0.1 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment 3Beta_HSD PF01073.19 OAP62233.1 - 1.5e-60 204.6 0.0 2.2e-60 204.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 OAP62233.1 - 3.5e-39 134.7 0.0 4.6e-39 134.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAP62233.1 - 4.1e-21 75.7 0.0 5.3e-19 68.8 0.0 2.1 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 OAP62233.1 - 1.4e-18 67.0 0.0 2.1e-18 66.4 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.17 OAP62233.1 - 2.8e-16 59.5 0.0 6.3e-16 58.3 0.0 1.7 1 1 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 OAP62233.1 - 1.4e-12 47.4 0.0 8.5e-11 41.5 0.0 2.2 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.10 OAP62233.1 - 1.5e-12 47.8 0.0 2.5e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 OAP62233.1 - 9.9e-08 32.1 0.0 1.7e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 OAP62233.1 - 0.00029 21.1 0.0 0.0007 19.9 0.0 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain adh_short PF00106.25 OAP62233.1 - 0.00036 20.1 0.0 0.0006 19.3 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase TrkA_N PF02254.18 OAP62233.1 - 0.026 14.8 1.1 0.091 13.0 0.0 2.5 3 1 0 3 3 2 0 TrkA-N domain NmrA PF05368.13 OAP62233.1 - 0.051 13.1 0.0 0.069 12.7 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family Peptidase_M57 PF12388.8 OAP62233.1 - 0.14 11.8 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Spt5-NGN PF03439.13 OAP62234.1 - 1.2e-23 82.8 0.0 2.5e-23 81.8 0.0 1.6 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.8 OAP62234.1 - 2e-17 63.9 10.5 2e-17 63.9 10.5 4.0 2 1 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal CTD PF12815.7 OAP62234.1 - 2.2e-09 37.7 29.2 2.2e-09 37.7 29.2 5.0 3 1 1 4 4 4 1 Spt5 C-terminal nonapeptide repeat binding Spt4 KOW PF00467.29 OAP62234.1 - 5.8e-07 29.2 12.9 0.018 15.0 1.5 5.3 5 0 0 5 5 5 2 KOW motif DUF3912 PF13051.6 OAP62234.1 - 0.15 12.4 1.1 14 6.1 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3912) Myosin_N PF02736.19 OAP62234.1 - 7.6 6.5 7.8 0.69 9.8 0.6 3.0 3 0 0 3 3 3 0 Myosin N-terminal SH3-like domain Aldedh PF00171.22 OAP62235.1 - 2.6e-183 609.8 0.1 2.9e-183 609.6 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 OAP62235.1 - 0.024 14.1 0.0 0.11 11.9 0.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1487) IPI_T4 PF11634.8 OAP62235.1 - 0.13 12.3 0.0 12 5.9 0.0 2.6 2 0 0 2 2 2 0 Nuclease inhibitor from bacteriophage T4 EVE PF01878.18 OAP62236.1 - 1.7e-49 167.5 0.0 2.6e-49 167.0 0.0 1.3 1 0 0 1 1 1 1 EVE domain bZIP_2 PF07716.15 OAP62237.1 - 0.00053 20.0 5.7 0.00098 19.2 5.7 1.4 1 0 0 1 1 1 1 Basic region leucine zipper SGL PF08450.12 OAP62238.1 - 1.5e-69 234.3 0.1 1.8e-69 234.1 0.1 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region DUF5074 PF16819.5 OAP62238.1 - 0.0053 16.8 0.0 0.14 12.2 0.0 2.3 1 1 1 2 2 2 1 Domain of unknown function (DUF5074) Glu_cyclase_2 PF05096.12 OAP62238.1 - 0.054 12.9 0.0 6.6 6.1 0.0 2.2 2 0 0 2 2 2 0 Glutamine cyclotransferase Phytase-like PF13449.6 OAP62238.1 - 0.091 12.7 0.0 0.51 10.2 0.0 2.0 2 0 0 2 2 2 0 Esterase-like activity of phytase DAHP_synth_2 PF01474.16 OAP62240.1 - 6.2e-193 641.2 0.0 8.4e-192 637.5 0.0 1.9 1 1 0 1 1 1 1 Class-II DAHP synthetase family Glyco_hydro_17 PF00332.18 OAP62242.1 - 2.1e-05 24.3 2.2 7.2e-05 22.5 1.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 17 Acyl-CoA_dh_1 PF00441.24 OAP62243.1 - 3.7e-41 140.8 0.4 5e-41 140.4 0.4 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 OAP62243.1 - 1.6e-20 73.1 0.1 3.2e-20 72.1 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 OAP62243.1 - 2.1e-19 70.2 0.0 5.1e-19 69.0 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Cyt-b5 PF00173.28 OAP62243.1 - 1.2e-18 67.0 0.2 2.3e-18 66.1 0.2 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_2 PF08028.11 OAP62243.1 - 2.4e-09 37.6 0.0 3.5e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain RecG_wedge PF17191.4 OAP62243.1 - 0.15 11.7 0.1 0.25 10.9 0.1 1.3 1 0 0 1 1 1 0 RecG wedge domain Kelch_3 PF13415.6 OAP62244.1 - 1.3e-15 57.2 5.0 6e-10 39.2 0.0 5.5 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_4 PF13418.6 OAP62244.1 - 2e-15 56.5 4.7 1.3e-05 25.1 0.0 5.3 4 1 0 4 4 4 2 Galactose oxidase, central domain Kelch_5 PF13854.6 OAP62244.1 - 5.6e-14 51.8 4.5 1.8e-05 24.6 0.0 4.2 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.6 OAP62244.1 - 6.4e-12 45.3 10.0 0.0013 18.9 0.0 5.7 4 1 1 5 5 5 3 Kelch motif Kelch_1 PF01344.25 OAP62244.1 - 1.8e-11 43.4 0.2 0.00099 18.6 0.0 4.3 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.15 OAP62244.1 - 3.5e-09 36.3 1.8 1.8e-05 24.5 0.0 4.8 4 1 0 4 4 4 2 Kelch motif BTB PF00651.31 OAP62244.1 - 0.0011 19.2 0.0 0.06 13.6 0.0 2.2 2 0 0 2 2 2 1 BTB/POZ domain AhpC-TSA PF00578.21 OAP62245.1 - 3.1e-31 107.9 0.0 4.4e-31 107.4 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 OAP62245.1 - 1.1e-13 51.1 0.0 1.5e-13 50.7 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 OAP62245.1 - 8.1e-12 44.8 0.3 1.5e-11 43.9 0.3 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Ank_2 PF12796.7 OAP62246.1 - 1.1e-10 41.9 0.0 1.6e-10 41.4 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OAP62246.1 - 7.1e-10 39.0 0.4 1e-05 25.7 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 OAP62246.1 - 7.3e-08 32.5 0.8 1.1e-05 25.6 0.4 2.3 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 OAP62246.1 - 1.1e-07 32.2 0.1 0.0071 16.9 0.0 3.1 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAP62246.1 - 5.6e-07 29.4 0.1 0.0015 18.8 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Agglutinin_C PF18021.1 OAP62246.1 - 0.13 12.8 0.1 2.4 8.7 0.0 2.1 2 0 0 2 2 2 0 Agglutinin C-terminal GMC_oxred_N PF00732.19 OAP62248.1 - 2.1e-68 230.9 0.0 3.3e-68 230.2 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAP62248.1 - 6.6e-37 127.2 0.0 1.1e-36 126.5 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 OAP62248.1 - 1.1e-06 28.0 0.3 0.00033 19.9 0.1 2.4 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 OAP62248.1 - 6.4e-06 26.0 0.4 0.00031 20.5 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 OAP62248.1 - 1.8e-05 23.9 0.1 3.1e-05 23.2 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 OAP62248.1 - 8.3e-05 22.0 0.0 0.0082 15.4 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAP62248.1 - 0.00012 22.2 0.2 0.00029 21.0 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 OAP62248.1 - 0.00035 19.9 0.0 0.00082 18.7 0.0 1.5 1 0 0 1 1 1 1 Thi4 family Imm40 PF15569.6 OAP62248.1 - 0.0044 17.1 0.0 0.012 15.7 0.0 1.7 1 1 0 1 1 1 1 Immunity protein 40 Pyr_redox_3 PF13738.6 OAP62248.1 - 0.0059 15.9 0.1 0.31 10.2 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAP62248.1 - 0.041 12.6 0.1 0.068 11.9 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein FAD_oxidored PF12831.7 OAP62248.1 - 0.3 10.4 0.7 28 3.9 0.0 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase GTP_EFTU PF00009.27 OAP62249.1 - 2.5e-58 196.8 0.2 5.2e-58 195.8 0.2 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 OAP62249.1 - 4.6e-34 116.4 0.0 1.1e-33 115.1 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.18 OAP62249.1 - 3.4e-33 114.0 0.1 6.2e-33 113.1 0.1 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 OAP62249.1 - 4.3e-21 74.7 0.0 1.4e-20 73.1 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 OAP62249.1 - 5.3e-13 49.2 0.1 1.5e-12 47.7 0.1 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 OAP62249.1 - 2.3e-07 30.7 0.0 7.1e-07 29.1 0.0 1.9 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain ATP_bind_1 PF03029.17 OAP62249.1 - 0.032 14.0 0.1 0.11 12.3 0.0 1.9 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 OAP62249.1 - 0.1 12.7 0.0 0.25 11.4 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase Methyltransf_3 PF01596.17 OAP62250.1 - 3.4e-24 85.2 0.0 4.6e-24 84.8 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 OAP62250.1 - 5.4e-12 46.7 0.0 8.1e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAP62250.1 - 0.0027 18.3 0.0 0.0062 17.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAP62250.1 - 0.093 12.6 0.0 0.32 10.8 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Syja_N PF02383.18 OAP62251.1 - 1.4e-90 303.9 0.0 1.7e-90 303.6 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain Ras PF00071.22 OAP62252.1 - 2e-59 199.8 0.4 2.3e-59 199.6 0.4 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAP62252.1 - 1.6e-36 125.1 0.2 3.7e-36 124.0 0.1 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAP62252.1 - 7.4e-15 54.8 0.1 9.1e-15 54.5 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OAP62252.1 - 1e-06 28.8 0.0 1.7e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OAP62252.1 - 1.5e-06 27.7 0.1 1.8e-06 27.5 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 OAP62252.1 - 2.5e-06 27.2 0.0 3.5e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OAP62252.1 - 0.0001 22.2 1.2 0.28 11.1 0.0 2.4 1 1 2 3 3 3 2 RsgA GTPase AAA_16 PF13191.6 OAP62252.1 - 0.014 15.8 0.1 0.023 15.1 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 OAP62252.1 - 0.045 14.0 0.1 2.7 8.3 0.0 2.3 1 1 1 2 2 2 0 AAA domain TniB PF05621.11 OAP62252.1 - 0.15 11.5 0.0 0.44 9.9 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein TLD PF07534.16 OAP62253.1 - 9.6e-21 74.5 0.0 2e-20 73.4 0.0 1.6 1 0 0 1 1 1 1 TLD Mur_ligase_M PF08245.12 OAP62254.1 - 0.00019 21.5 2.3 0.00095 19.2 1.2 2.5 1 1 1 2 2 2 1 Mur ligase middle domain Kelch_5 PF13854.6 OAP62255.1 - 9.1e-15 54.3 2.3 1.1e-11 44.4 0.2 3.9 3 0 0 3 3 3 1 Kelch motif Kelch_4 PF13418.6 OAP62255.1 - 0.00013 21.9 6.0 0.11 12.6 0.2 5.0 4 1 0 4 4 4 1 Galactose oxidase, central domain Kelch_6 PF13964.6 OAP62255.1 - 0.00021 21.4 1.4 0.04 14.2 0.1 4.3 4 0 0 4 4 4 1 Kelch motif Kelch_2 PF07646.15 OAP62255.1 - 0.00048 20.0 1.9 1.2 9.2 0.0 5.3 5 0 0 5 5 5 1 Kelch motif Rax2 PF12768.7 OAP62255.1 - 0.00063 19.3 0.1 0.0026 17.3 0.0 2.0 2 0 0 2 2 2 1 Cortical protein marker for cell polarity SKG6 PF08693.10 OAP62255.1 - 0.0016 17.8 3.6 0.0041 16.5 3.6 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Kelch_1 PF01344.25 OAP62255.1 - 0.0095 15.5 6.4 0.055 13.1 0.1 4.4 4 1 0 4 4 4 1 Kelch motif EndoU_bacteria PF14436.6 OAP62255.1 - 0.027 14.8 0.1 0.097 13.0 0.1 2.0 1 0 0 1 1 1 0 Bacterial EndoU nuclease Stevor PF17410.2 OAP62255.1 - 0.067 12.7 0.1 0.11 12.1 0.1 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame EphA2_TM PF14575.6 OAP62255.1 - 0.082 13.8 0.0 0.18 12.7 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Amidohydro_1 PF01979.20 OAP62257.1 - 5e-19 68.8 0.9 7e-19 68.3 0.9 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 OAP62257.1 - 2.9e-08 33.6 2.1 1.9e-05 24.3 0.4 2.7 2 1 0 2 2 2 2 Amidohydrolase family NAD_binding_2 PF03446.15 OAP62258.1 - 1.1e-29 103.7 0.0 1.4e-29 103.3 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 OAP62258.1 - 4.8e-07 30.1 0.0 8.3e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Shikimate_DH PF01488.20 OAP62258.1 - 4.8e-05 23.4 0.0 8e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 OAP62258.1 - 0.00013 22.5 0.0 0.00026 21.5 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA PF01408.22 OAP62258.1 - 0.00072 20.4 0.0 0.0012 19.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold OCD_Mu_crystall PF02423.15 OAP62258.1 - 0.0014 17.7 0.0 0.0019 17.2 0.0 1.2 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family 2-Hacid_dh_C PF02826.19 OAP62258.1 - 0.0037 16.7 0.0 0.0057 16.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 OAP62258.1 - 0.005 16.4 0.0 0.037 13.6 0.0 2.2 1 1 2 3 3 3 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain ApbA PF02558.16 OAP62258.1 - 0.017 14.7 0.0 0.088 12.5 0.0 2.0 1 1 1 2 2 2 0 Ketopantoate reductase PanE/ApbA Abhydrolase_1 PF00561.20 OAP62259.1 - 8.5e-28 97.7 0.0 7.5e-25 88.0 0.0 2.0 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAP62259.1 - 4.1e-24 85.2 0.0 6.3e-24 84.6 0.0 1.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OAP62259.1 - 1.7e-21 77.9 0.0 2e-21 77.7 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 OAP62259.1 - 7.7e-09 36.0 0.0 9.2e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 Thioesterase domain Ser_hydrolase PF06821.13 OAP62259.1 - 2.2e-07 30.9 0.1 0.00095 19.1 0.0 2.2 2 0 0 2 2 2 2 Serine hydrolase Abhydrolase_2 PF02230.16 OAP62259.1 - 3.2e-06 27.1 0.1 0.028 14.2 0.0 3.0 1 1 2 3 3 3 2 Phospholipase/Carboxylesterase Esterase PF00756.20 OAP62259.1 - 1.7e-05 24.6 0.0 6.7e-05 22.7 0.0 2.0 2 1 0 2 2 2 1 Putative esterase Abhydrolase_5 PF12695.7 OAP62259.1 - 4.6e-05 23.2 0.1 0.0025 17.6 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family PGAP1 PF07819.13 OAP62259.1 - 4.7e-05 23.2 0.3 0.0042 16.8 0.0 2.2 1 1 0 2 2 2 1 PGAP1-like protein DUF915 PF06028.11 OAP62259.1 - 9.5e-05 21.8 0.0 0.13 11.6 0.0 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase of unknown function (DUF915) DLH PF01738.18 OAP62259.1 - 0.00014 21.5 0.0 0.021 14.4 0.0 2.5 1 1 0 2 2 2 1 Dienelactone hydrolase family Ndr PF03096.14 OAP62259.1 - 0.0003 19.6 0.0 0.00035 19.4 0.0 1.2 1 0 0 1 1 1 1 Ndr family BAAT_C PF08840.11 OAP62259.1 - 0.00045 20.2 0.0 0.0014 18.6 0.0 1.7 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_3 PF07859.13 OAP62259.1 - 0.0011 18.9 0.1 0.002 18.0 0.1 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 OAP62259.1 - 0.0054 15.7 0.1 0.029 13.3 0.0 2.2 3 0 0 3 3 3 1 Chlorophyllase enzyme Palm_thioest PF02089.15 OAP62259.1 - 0.0087 15.9 0.0 0.011 15.6 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase LIDHydrolase PF10230.9 OAP62259.1 - 0.024 14.2 0.0 0.036 13.6 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase UPF0227 PF05728.12 OAP62259.1 - 0.052 13.5 0.0 0.076 12.9 0.0 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0227) Lipase_3 PF01764.25 OAP62259.1 - 0.054 13.4 0.0 0.084 12.7 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF676 PF05057.14 OAP62259.1 - 0.094 12.2 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Phenol_Hydrox PF02332.18 OAP62260.1 - 0.015 14.9 0.1 0.022 14.3 0.1 1.2 1 0 0 1 1 1 0 Methane/Phenol/Toluene Hydroxylase Fungal_trans PF04082.18 OAP62261.1 - 2.1e-25 89.3 0.0 3.1e-25 88.7 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP62261.1 - 4.9e-07 29.8 10.8 9.9e-07 28.8 10.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NMT_C PF02799.15 OAP62262.1 - 5.2e-85 284.2 0.0 7.8e-85 283.7 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 OAP62262.1 - 8.5e-70 233.7 0.1 1.5e-68 229.7 0.0 2.2 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_9 PF13527.7 OAP62262.1 - 0.00049 20.2 0.2 0.02 15.0 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAP62262.1 - 0.1 12.8 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family FR47 PF08445.10 OAP62262.1 - 0.16 12.0 0.0 4.2 7.4 0.0 2.3 2 0 0 2 2 2 0 FR47-like protein DUF3987 PF13148.6 OAP62262.1 - 0.18 10.8 1.3 0.27 10.2 0.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) F-box-like PF12937.7 OAP62263.1 - 8.6e-05 22.3 0.9 0.0002 21.2 0.1 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 OAP62263.1 - 0.0028 17.5 0.0 0.0077 16.1 0.0 1.7 1 0 0 1 1 1 1 F-box domain XPG_N PF00752.17 OAP62264.1 - 8.4e-35 119.3 0.0 2.1e-34 118.0 0.0 1.8 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 OAP62264.1 - 1.7e-24 86.0 0.0 4.3e-24 84.7 0.0 1.8 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.20 OAP62264.1 - 5.8e-05 23.6 0.0 0.00023 21.7 0.0 2.0 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold UIM PF02809.20 OAP62264.1 - 0.0058 16.5 3.7 0.0058 16.5 3.7 3.5 3 0 0 3 3 3 1 Ubiquitin interaction motif HHH_5 PF14520.6 OAP62264.1 - 0.045 14.4 0.0 0.19 12.4 0.0 2.0 2 0 0 2 2 2 0 Helix-hairpin-helix domain HHH_2 PF12826.7 OAP62264.1 - 0.095 12.8 0.0 0.27 11.4 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif WD40 PF00400.32 OAP62265.1 - 7e-23 80.5 5.2 4.2e-05 24.2 0.1 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAP62265.1 - 5.4e-13 49.1 0.0 7.1e-08 32.6 0.0 4.5 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OAP62265.1 - 9.8e-05 22.3 0.0 0.057 13.3 0.0 2.5 1 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 OAP62265.1 - 0.00063 19.6 0.4 0.4 10.7 0.1 3.4 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat WD40_like PF17005.5 OAP62265.1 - 0.0053 16.1 0.0 0.023 14.1 0.0 1.9 2 0 0 2 2 2 1 WD40-like domain PSII_BNR PF14870.6 OAP62265.1 - 0.028 13.7 0.1 0.061 12.6 0.1 1.5 2 0 0 2 2 2 0 Photosynthesis system II assembly factor YCF48 MMS1_N PF10433.9 OAP62265.1 - 0.12 10.9 0.0 0.24 10.0 0.0 1.4 1 0 0 1 1 1 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term Metallophos PF00149.28 OAP62266.1 - 1.2e-35 123.9 0.2 1.7e-35 123.4 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 OAP62266.1 - 3.8e-16 59.3 0.0 6.9e-16 58.4 0.0 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain LSM PF01423.22 OAP62267.1 - 5.7e-09 35.5 0.0 8.3e-09 35.0 0.0 1.3 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 OAP62267.1 - 2.2e-07 30.9 0.1 7e-07 29.3 0.1 1.7 1 1 0 1 1 1 1 Ataxin 2 SM domain MOLO1 PF17175.4 OAP62268.1 - 0.029 14.5 0.0 0.16 12.1 0.0 2.1 2 0 0 2 2 2 0 Modulator of levamisole receptor-1 LIN37 PF15306.6 OAP62268.1 - 6.1 7.0 11.4 98 3.1 9.2 2.6 1 1 0 1 1 1 0 LIN37 N-SET PF11764.8 OAP62269.1 - 8.7e-45 152.9 0.0 8.7e-45 152.9 0.0 2.5 3 0 0 3 3 3 1 COMPASS (Complex proteins associated with Set1p) component N SET_assoc PF11767.8 OAP62269.1 - 3.3e-24 84.3 0.5 6.9e-24 83.3 0.5 1.6 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated SET PF00856.28 OAP62269.1 - 9.3e-21 74.9 0.1 9.3e-21 74.9 0.1 2.9 2 1 0 2 2 2 1 SET domain RRM_1 PF00076.22 OAP62269.1 - 0.00021 21.0 0.0 0.00067 19.4 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Trm112p PF03966.16 OAP62270.1 - 6.4e-15 55.5 0.0 1.1e-14 54.7 0.0 1.4 1 1 0 1 1 1 1 Trm112p-like protein Gpr1_Fun34_YaaH PF01184.19 OAP62272.1 - 1e-89 299.6 18.4 1.2e-89 299.4 18.4 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Memo PF01875.17 OAP62273.1 - 9.8e-63 211.8 0.0 1.2e-62 211.5 0.0 1.1 1 0 0 1 1 1 1 Memo-like protein GEP5 PF17053.5 OAP62273.1 - 0.15 11.9 0.1 0.25 11.1 0.1 1.3 1 0 0 1 1 1 0 Genetic interactor of prohibitin 5 DUF5615 PF18480.1 OAP62274.1 - 0.068 12.9 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5615) zf-RING_2 PF13639.6 OAP62275.1 - 0.0007 19.9 8.0 0.0012 19.1 8.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-ANAPC11 PF12861.7 OAP62275.1 - 0.0083 16.2 2.3 0.014 15.5 2.3 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Tropomyosin_1 PF12718.7 OAP62275.1 - 0.012 15.7 0.6 0.024 14.8 0.6 1.4 1 0 0 1 1 1 0 Tropomyosin like Rad50_zn_hook PF04423.14 OAP62275.1 - 0.051 13.4 0.0 0.14 12.0 0.0 1.8 1 0 0 1 1 1 0 Rad50 zinc hook motif zf-rbx1 PF12678.7 OAP62275.1 - 0.079 13.3 6.1 0.17 12.2 6.1 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain C1_2 PF03107.16 OAP62275.1 - 0.15 12.4 2.3 0.25 11.7 0.3 2.2 2 0 0 2 2 2 0 C1 domain DUF2256 PF10013.9 OAP62275.1 - 0.17 12.1 1.3 7.2 6.8 0.2 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) Prok-RING_1 PF14446.6 OAP62275.1 - 0.61 10.1 8.2 2.7 8.0 8.6 1.9 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 zf-C3HC4_3 PF13920.6 OAP62275.1 - 0.62 10.0 8.6 1.5 8.8 8.8 1.5 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAP62275.1 - 0.86 9.5 8.9 1.5 8.8 8.9 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 OAP62275.1 - 1.4 8.6 6.9 2.7 7.7 6.9 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 OAP62275.1 - 1.7 8.9 7.2 3.3 8.0 7.2 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING_5 PF14634.6 OAP62275.1 - 9.6 6.3 7.8 17 5.5 7.8 1.4 1 0 0 1 1 1 0 zinc-RING finger domain Cyt-b5 PF00173.28 OAP62276.1 - 9.1e-17 61.0 0.0 1.5e-16 60.3 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FKBP_C PF00254.28 OAP62277.1 - 2.5e-32 111.0 0.0 3.1e-32 110.8 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase CoA_transf_3 PF02515.17 OAP62278.1 - 0.2 10.7 2.2 0.3 10.2 2.2 1.2 1 0 0 1 1 1 0 CoA-transferase family III UvrD_C PF13361.6 OAP62280.1 - 2.1e-60 205.0 0.1 5.8e-58 196.9 0.0 2.6 2 1 0 2 2 2 2 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.21 OAP62280.1 - 2.6e-59 201.3 0.1 1.1e-57 196.0 0.0 2.8 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 OAP62280.1 - 4.7e-32 111.3 0.0 2.1e-31 109.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain UvrD_C_2 PF13538.6 OAP62280.1 - 5.1e-14 51.8 0.7 1.2e-13 50.7 0.0 2.0 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 OAP62280.1 - 1.5e-08 34.6 0.0 6e-05 22.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 OAP62280.1 - 8.5e-07 28.9 0.2 0.027 14.2 0.0 3.2 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_12 PF13087.6 OAP62280.1 - 4.5e-05 23.1 0.0 0.0019 17.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 OAP62280.1 - 0.0054 16.5 0.1 0.025 14.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 OAP62280.1 - 0.018 15.3 2.5 2.7 8.2 0.1 3.0 3 0 0 3 3 3 0 AAA domain N_formyltrans_C PF18216.1 OAP62280.1 - 0.14 11.8 0.0 0.4 10.4 0.0 1.7 1 0 0 1 1 1 0 N-formyltransferase dimerization C-terminal domain FAD_binding_3 PF01494.19 OAP62283.1 - 4.4e-17 62.4 0.1 1.3e-09 37.8 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 OAP62283.1 - 5.7e-10 38.9 0.6 0.0007 18.9 0.2 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAP62283.1 - 7.9e-09 35.5 6.9 0.0012 18.5 0.0 2.4 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAP62283.1 - 6.7e-07 29.4 0.9 1.6e-06 28.3 0.9 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 OAP62283.1 - 1.1e-05 25.9 1.0 0.018 15.6 0.5 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 OAP62283.1 - 3.2e-05 23.4 0.3 0.037 13.3 0.0 2.5 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 OAP62283.1 - 0.0003 20.2 1.8 0.19 10.9 3.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAP62283.1 - 0.00031 20.7 0.1 0.00086 19.3 0.1 1.7 1 1 0 1 1 1 1 FAD-NAD(P)-binding Thi4 PF01946.17 OAP62283.1 - 0.0006 19.1 0.7 0.0011 18.2 0.7 1.4 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 OAP62283.1 - 0.00065 18.5 4.3 0.045 12.4 2.7 2.1 2 0 0 2 2 2 2 HI0933-like protein GIDA PF01134.22 OAP62283.1 - 0.0013 17.9 4.8 0.0034 16.5 4.3 1.9 3 0 0 3 3 3 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 OAP62283.1 - 0.0013 18.1 5.0 0.0028 17.1 5.0 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OAP62283.1 - 0.0014 17.8 5.2 0.0023 17.1 4.6 1.6 2 0 0 2 2 2 1 FAD binding domain Trp_halogenase PF04820.14 OAP62283.1 - 0.0022 16.9 6.1 0.17 10.7 3.3 2.3 1 1 1 2 2 2 2 Tryptophan halogenase Lycopene_cycl PF05834.12 OAP62283.1 - 0.0043 16.1 2.1 0.24 10.4 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein 3HCDH_N PF02737.18 OAP62283.1 - 0.13 12.1 1.1 0.26 11.2 1.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SE PF08491.10 OAP62283.1 - 0.13 11.2 0.0 0.26 10.3 0.0 1.4 2 0 0 2 2 2 0 Squalene epoxidase Rossmann-like PF10727.9 OAP62283.1 - 0.28 11.0 1.4 1.3 8.9 0.8 2.1 2 0 0 2 2 2 0 Rossmann-like domain AlaDh_PNT_C PF01262.21 OAP62283.1 - 0.52 9.6 2.5 1 8.6 2.5 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain F-box-like PF12937.7 OAP62284.1 - 0.00045 20.0 0.6 0.0013 18.6 0.6 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAP62284.1 - 0.00061 19.6 0.3 0.0017 18.2 0.3 1.8 1 0 0 1 1 1 1 F-box domain Glyco_hydro_36C PF16874.5 OAP62285.1 - 0.0067 16.9 0.1 2.4 8.7 0.0 2.5 3 0 0 3 3 3 2 Glycosyl hydrolase family 36 C-terminal domain IBR PF01485.21 OAP62286.1 - 2.4e-07 30.8 3.0 2.4e-07 30.8 3.0 2.9 2 1 0 2 2 2 1 IBR domain, a half RING-finger domain zf-C3HC4_4 PF15227.6 OAP62286.1 - 0.029 14.5 19.5 0.029 14.5 19.5 3.3 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING Cyclin_N PF00134.23 OAP62287.1 - 2.4e-38 130.8 1.1 1.1e-36 125.4 0.2 2.2 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 OAP62287.1 - 8.3e-08 32.3 0.2 2.2e-07 31.0 0.2 1.8 1 1 0 1 1 1 1 Cyclin, C-terminal domain PQ-loop PF04193.14 OAP62289.1 - 5.5e-24 83.7 6.4 6.7e-15 54.6 1.1 2.4 2 0 0 2 2 2 2 PQ loop repeat tRNA-synt_2 PF00152.20 OAP62290.1 - 7.2e-88 294.7 0.0 1e-87 294.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) Aminotran_1_2 PF00155.21 OAP62290.1 - 2e-28 99.6 0.0 3.2e-28 98.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 OAP62290.1 - 5.3e-05 22.3 0.0 8.9e-05 21.6 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 OAP62290.1 - 5.4e-05 21.9 0.0 8.2e-05 21.3 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 OAP62290.1 - 0.0047 16.3 0.0 0.016 14.5 0.0 1.7 2 0 0 2 2 2 1 Beta-eliminating lyase tRNA-synt_2d PF01409.20 OAP62290.1 - 0.22 11.0 0.0 0.97 8.9 0.0 1.9 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) ABC2_membrane PF01061.24 OAP62291.1 - 3.5e-34 118.1 21.1 6.8e-34 117.1 21.1 1.5 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 OAP62291.1 - 1.4e-26 93.7 0.0 2.3e-26 93.0 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 OAP62291.1 - 3.3e-05 23.9 0.1 0.29 10.9 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 OAP62291.1 - 9.9e-05 21.6 30.8 0.00017 20.9 27.0 2.2 1 1 1 2 2 2 1 ABC-2 family transporter protein AAA_29 PF13555.6 OAP62291.1 - 0.0011 18.6 0.1 0.0025 17.5 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 OAP62291.1 - 0.0059 16.5 0.4 0.013 15.4 0.1 1.7 2 0 0 2 2 2 1 RsgA GTPase SMC_N PF02463.19 OAP62291.1 - 0.044 13.2 0.0 0.49 9.8 0.0 2.2 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 OAP62291.1 - 0.07 13.4 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 OAP62291.1 - 0.12 12.9 0.0 0.25 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 OAP62291.1 - 0.13 12.7 0.2 0.26 11.8 0.2 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 OAP62291.1 - 0.14 12.3 0.0 0.29 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Glycophorin_A PF01102.18 OAP62291.1 - 0.16 12.2 0.0 0.42 10.9 0.0 1.7 1 0 0 1 1 1 0 Glycophorin A hEGF PF12661.7 OAP62291.1 - 0.18 12.5 15.9 0.23 12.1 3.6 4.1 3 0 0 3 3 3 0 Human growth factor-like EGF AAA_25 PF13481.6 OAP62291.1 - 0.21 11.1 0.0 0.51 9.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain MaoC_dehydratas PF01575.19 OAP62292.1 - 0.0061 16.1 0.0 0.012 15.2 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain ZZ PF00569.17 OAP62293.1 - 3.1e-05 23.7 8.9 3.1e-05 23.7 8.9 3.0 3 0 0 3 3 3 1 Zinc finger, ZZ type zf-4CXXC_R1 PF10497.9 OAP62293.1 - 7.2e-05 22.9 15.9 7.2e-05 22.9 15.9 2.6 2 0 0 2 2 2 1 Zinc-finger domain of monoamine-oxidase A repressor R1 JmjC PF02373.22 OAP62293.1 - 0.00028 21.3 0.0 0.00064 20.1 0.0 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase FlxA PF14282.6 OAP62293.1 - 0.0047 16.9 1.2 0.009 16.0 1.2 1.3 1 0 0 1 1 1 1 FlxA-like protein Cupin_2 PF07883.11 OAP62293.1 - 0.1 12.3 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Cupin domain AA_permease PF00324.21 OAP62294.1 - 6.3e-113 377.9 42.2 7.6e-113 377.6 42.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAP62294.1 - 3.1e-26 92.2 46.6 3.8e-26 91.9 46.6 1.0 1 0 0 1 1 1 1 Amino acid permease Smim3 PF17307.2 OAP62294.1 - 0.12 11.9 2.1 0.53 9.8 2.1 2.1 1 0 0 1 1 1 0 Small integral membrane protein 3 p450 PF00067.22 OAP62295.1 - 1.2e-59 202.3 0.0 3.7e-59 200.7 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 Importin_rep_4 PF18808.1 OAP62297.1 - 2.2e-35 120.8 1.5 9.6e-34 115.5 1.4 3.7 2 1 1 3 3 3 1 Importin repeat HEAT_EZ PF13513.6 OAP62297.1 - 8.1e-23 80.5 6.8 2e-08 34.5 0.1 9.1 9 1 1 10 10 10 2 HEAT-like repeat Importin_rep_5 PF18816.1 OAP62297.1 - 8.7e-21 74.0 3.5 3e-20 72.3 3.5 2.0 1 0 0 1 1 1 1 Importin repeat HEAT PF02985.22 OAP62297.1 - 4.2e-17 60.8 11.2 0.0044 17.2 0.0 11.6 13 0 0 13 13 10 3 HEAT repeat HEAT_2 PF13646.6 OAP62297.1 - 5.7e-17 61.9 4.5 5.8e-05 23.4 0.0 8.1 6 2 2 8 8 7 3 HEAT repeats Importin_rep_6 PF18829.1 OAP62297.1 - 1.1e-13 51.2 1.7 3.3e-12 46.5 0.1 3.2 3 0 0 3 3 3 1 Importin repeat 6 DUF3385 PF11865.8 OAP62297.1 - 1.7e-09 37.8 0.9 0.032 14.1 0.0 6.4 4 4 1 5 5 5 1 Domain of unknown function (DUF3385) Vac14_Fab1_bd PF12755.7 OAP62297.1 - 3e-09 37.4 0.0 0.054 14.1 0.0 5.8 5 1 1 6 6 5 2 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 OAP62297.1 - 1.2e-06 28.3 0.0 0.033 13.7 0.0 4.7 4 1 1 5 5 5 2 CLASP N terminal MMS19_C PF12460.8 OAP62297.1 - 1.9e-06 27.2 3.1 3.5e-06 26.4 0.2 3.0 3 1 1 4 4 4 1 RNAPII transcription regulator C-terminal RIX1 PF08167.12 OAP62297.1 - 5.2e-06 26.3 0.0 0.00049 19.9 0.0 3.5 2 1 1 3 3 3 1 rRNA processing/ribosome biogenesis Arm PF00514.23 OAP62297.1 - 3.5e-05 23.7 7.3 0.04 14.0 0.0 5.2 5 0 0 5 5 4 1 Armadillo/beta-catenin-like repeat DRIM PF07539.12 OAP62297.1 - 7.7e-05 21.2 0.1 0.033 12.5 0.3 3.5 2 1 1 3 3 3 1 Down-regulated in metastasis Cnd1 PF12717.7 OAP62297.1 - 7.9e-05 22.7 0.0 0.19 11.8 0.0 4.9 3 3 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Xpo1 PF08389.12 OAP62297.1 - 0.0012 18.9 0.5 0.66 10.0 0.0 4.5 5 1 0 5 5 4 1 Exportin 1-like protein RTP1_C1 PF10363.9 OAP62297.1 - 0.0033 17.6 1.7 0.21 11.8 0.2 4.5 5 1 2 7 7 6 1 Required for nuclear transport of RNA pol II C-terminus 1 Adaptin_N PF01602.20 OAP62297.1 - 0.0039 15.8 0.2 1.3 7.5 0.1 3.7 3 1 1 4 4 4 1 Adaptin N terminal region DSHCT PF08148.12 OAP62297.1 - 0.0046 16.6 0.2 0.028 14.1 0.0 2.5 3 0 0 3 3 3 1 DSHCT (NUC185) domain Cohesin_HEAT PF12765.7 OAP62297.1 - 0.0057 16.9 0.0 1.4 9.3 0.0 3.7 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion IFRD PF05004.13 OAP62297.1 - 0.01 15.0 0.4 0.37 9.8 0.1 3.5 2 2 0 2 2 2 0 Interferon-related developmental regulator (IFRD) Ecm29 PF13001.7 OAP62297.1 - 0.015 14.0 1.1 13 4.3 0.0 4.1 3 2 1 5 5 5 0 Proteasome stabiliser IBN_N PF03810.19 OAP62297.1 - 0.017 15.1 0.3 0.15 12.0 0.1 3.0 2 1 1 3 3 2 0 Importin-beta N-terminal domain TFCD_C PF12612.8 OAP62297.1 - 0.027 14.3 0.0 15 5.3 0.0 3.4 3 0 0 3 3 3 0 Tubulin folding cofactor D C terminal YihI PF04220.12 OAP62297.1 - 0.091 12.5 0.6 0.28 10.9 0.6 1.8 1 0 0 1 1 1 0 Der GTPase activator (YihI) DUF4042 PF13251.6 OAP62297.1 - 0.092 12.4 0.0 18 5.0 0.0 4.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4042) MIF4G_like_2 PF09090.11 OAP62297.1 - 0.11 12.0 0.4 0.38 10.2 0.1 2.0 2 0 0 2 2 2 0 MIF4G like V-ATPase_H_N PF03224.14 OAP62297.1 - 0.92 8.7 3.9 2.8 7.2 0.1 3.2 4 0 0 4 4 4 0 V-ATPase subunit H Bromodomain PF00439.25 OAP62298.1 - 1.4e-19 69.9 0.3 4.1e-19 68.4 0.3 1.8 1 0 0 1 1 1 1 Bromodomain Bromo_TP PF07524.13 OAP62298.1 - 0.00085 19.3 0.0 0.002 18.1 0.0 1.6 1 0 0 1 1 1 1 Bromodomain associated PBP1_TM PF14812.6 OAP62298.1 - 0.77 10.2 13.8 0.037 14.4 1.5 3.3 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal VanZ PF04892.12 OAP62299.1 - 2.3e-06 28.3 0.7 3.4e-06 27.7 0.7 1.3 1 0 0 1 1 1 1 VanZ like family NAD_binding_6 PF08030.12 OAP62300.1 - 4.5e-32 111.3 0.0 9.5e-32 110.3 0.0 1.6 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 OAP62300.1 - 2.6e-21 75.7 0.0 7e-21 74.4 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 OAP62300.1 - 2.5e-19 69.6 10.0 1.5e-18 67.2 7.3 2.3 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.21 OAP62300.1 - 0.18 12.4 0.0 0.69 10.6 0.0 2.0 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain MIS13 PF08202.11 OAP62303.1 - 8.6e-46 156.6 0.1 2.9e-45 154.9 0.0 1.9 2 0 0 2 2 2 1 Mis12-Mtw1 protein family FAD_binding_3 PF01494.19 OAP62304.1 - 4.2e-06 26.3 1.8 0.0074 15.6 0.1 3.0 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.24 OAP62304.1 - 0.00027 20.6 2.6 0.004 16.8 0.5 2.6 2 1 1 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAP62304.1 - 0.15 11.3 0.7 0.64 9.2 0.7 1.9 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase YbfN PF13982.6 OAP62306.1 - 0.0068 16.7 0.1 0.009 16.3 0.1 1.2 1 0 0 1 1 1 1 YbfN-like lipoprotein ADH_zinc_N PF00107.26 OAP62307.1 - 2.3e-25 89.1 0.1 4.3e-25 88.2 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAP62307.1 - 3.8e-25 87.9 1.0 7e-25 87.0 1.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 OAP62307.1 - 2.8e-07 30.3 0.0 4e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 OAP62307.1 - 0.00036 21.6 0.0 0.00064 20.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 OAP62307.1 - 0.025 14.5 0.0 0.075 13.0 0.0 1.9 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-associated Shikimate_DH PF01488.20 OAP62307.1 - 0.11 12.6 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 OAP62307.1 - 0.13 11.6 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DZR PF12773.7 OAP62307.1 - 0.18 11.8 4.2 0.58 10.2 4.2 1.8 1 1 0 1 1 1 0 Double zinc ribbon zf-ribbon_3 PF13248.6 OAP62307.1 - 0.73 9.3 8.1 0.16 11.4 1.5 2.5 2 0 0 2 2 2 0 zinc-ribbon domain Macoilin PF09726.9 OAP62308.1 - 0.064 11.8 2.4 0.059 11.9 2.4 1.1 1 0 0 1 1 1 0 Macoilin family RAP1 PF07218.11 OAP62308.1 - 0.61 8.3 14.4 0.84 7.8 14.4 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF1180 PF06679.12 OAP62308.1 - 2.6 8.5 14.8 9.8 6.6 9.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) 4HBT PF03061.22 OAP62309.1 - 5.6e-09 36.2 0.0 8.6e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily DUF2183 PF09949.9 OAP62309.1 - 0.12 12.7 0.1 1.9 8.9 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2183) BCOR PF15808.5 OAP62309.1 - 0.16 12.1 0.0 0.23 11.7 0.0 1.1 1 0 0 1 1 1 0 BCL-6 co-repressor, non-ankyrin-repeat region PBP PF01161.20 OAP62310.1 - 3.9e-14 53.1 0.0 4.7e-14 52.8 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein MFS_1 PF07690.16 OAP62311.1 - 3.5e-44 151.2 25.0 4.8e-44 150.7 22.9 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAP62311.1 - 3.1 6.6 24.8 0.24 10.2 9.9 2.8 2 1 1 3 3 3 0 Sugar (and other) transporter Cnd2 PF05786.14 OAP62312.1 - 1.1e-248 827.9 12.4 1.3e-248 827.6 12.4 1.0 1 0 0 1 1 1 1 Condensin complex subunit 2 CNDH2_N PF06278.11 OAP62312.1 - 0.13 12.5 1.2 0.34 11.1 0.0 2.3 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal EF-hand_4 PF12763.7 OAP62313.1 - 3.7e-24 84.7 0.0 2.9e-12 46.4 0.0 2.4 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand WH2 PF02205.20 OAP62313.1 - 2e-07 30.6 0.9 5.4e-07 29.2 0.9 1.8 1 0 0 1 1 1 1 WH2 motif DUF1720 PF08226.11 OAP62313.1 - 8.1e-05 23.0 33.2 8.1e-05 23.0 33.2 8.1 5 3 2 7 7 7 3 Domain of unknown function (DUF1720) EF-hand_7 PF13499.6 OAP62313.1 - 0.00086 19.7 0.0 0.11 13.0 0.0 2.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 OAP62313.1 - 0.0022 17.4 0.0 0.17 11.5 0.0 2.5 2 0 0 2 2 2 1 EF hand E3_binding PF02817.17 OAP62313.1 - 0.019 15.3 0.0 0.073 13.4 0.0 2.0 1 0 0 1 1 1 0 e3 binding domain EF-hand_8 PF13833.6 OAP62313.1 - 0.13 12.1 0.0 0.44 10.4 0.0 1.9 2 0 0 2 2 2 0 EF-hand domain pair Fungal_trans PF04082.18 OAP62314.1 - 3.6e-17 62.3 0.2 8.7e-17 61.0 0.1 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain FMO-like PF00743.19 OAP62315.1 - 1.5e-16 59.9 0.0 3.3e-16 58.8 0.0 1.5 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 OAP62315.1 - 2.6e-15 56.4 0.0 3e-13 49.7 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAP62315.1 - 6.7e-10 39.0 0.0 8.3e-07 29.2 0.0 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 OAP62315.1 - 1.2e-08 34.5 0.0 2.4e-07 30.3 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 OAP62315.1 - 4.4e-07 29.5 0.0 1.3e-06 27.9 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAP62315.1 - 9.1e-05 22.5 0.4 0.0046 17.0 0.1 3.3 3 1 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 OAP62315.1 - 0.00016 22.1 0.1 0.13 12.8 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 OAP62315.1 - 0.01 15.9 0.0 0.26 11.3 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 OAP62315.1 - 0.012 15.8 0.1 1.5 9.1 0.0 2.8 3 0 0 3 3 3 0 TrkA-N domain NAD_binding_7 PF13241.6 OAP62315.1 - 0.029 14.8 0.0 3.8 8.0 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding FAD_binding_3 PF01494.19 OAP62315.1 - 0.055 12.7 0.0 4.6 6.4 0.0 2.4 2 0 0 2 2 2 0 FAD binding domain IlvN PF07991.12 OAP62315.1 - 0.08 12.5 0.2 0.69 9.5 0.0 2.1 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain DUF1188 PF06690.11 OAP62315.1 - 0.11 12.0 0.0 12 5.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1188) 2-Hacid_dh_C PF02826.19 OAP62315.1 - 0.16 11.3 0.0 0.37 10.1 0.0 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Viral_DNA_bp PF00747.17 OAP62315.1 - 0.31 8.2 0.0 0.47 7.6 0.0 1.2 1 0 0 1 1 1 0 ssDNA binding protein RNA_pol_L_2 PF13656.6 OAP62316.1 - 1.6e-25 88.7 0.1 2.7e-25 87.9 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 OAP62316.1 - 5.2e-10 38.6 0.0 1e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain NMO PF03060.15 OAP62317.1 - 5.5e-32 111.5 9.8 2.8e-27 96.0 4.3 2.2 2 0 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.18 OAP62317.1 - 1.5e-10 40.7 1.3 2.1e-10 40.2 1.3 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 OAP62317.1 - 5.7e-09 35.4 0.6 1.8e-08 33.8 0.6 1.8 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 OAP62317.1 - 1.1e-05 24.8 0.8 1.9e-05 24.0 0.8 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.21 OAP62317.1 - 0.023 14.1 0.0 0.048 13.1 0.0 1.5 1 0 0 1 1 1 0 Histidine biosynthesis protein LSM PF01423.22 OAP62318.1 - 1.3e-16 60.1 0.0 1.4e-16 59.9 0.0 1.0 1 0 0 1 1 1 1 LSM domain Lipase_3 PF01764.25 OAP62319.1 - 5.1e-29 101.0 0.0 1e-28 100.0 0.0 1.5 1 1 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 OAP62319.1 - 8.9e-05 23.2 0.1 0.00014 22.6 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAP62319.1 - 0.00094 18.5 0.0 0.0015 17.8 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 OAP62319.1 - 0.0055 16.9 0.0 0.01 15.9 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.13 OAP62319.1 - 0.053 13.2 0.0 0.085 12.6 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein DUF2974 PF11187.8 OAP62319.1 - 0.056 13.0 0.0 0.27 10.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Abhydrolase_5 PF12695.7 OAP62319.1 - 0.059 13.1 0.0 0.096 12.4 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAP62319.1 - 0.082 12.5 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 OAP62321.1 - 2.4e-70 236.7 0.0 3e-70 236.4 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 OAP62321.1 - 7.7e-11 41.5 0.1 1.9e-10 40.2 0.1 1.5 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 OAP62321.1 - 7.3e-07 28.9 0.1 0.00081 18.9 0.1 2.6 2 1 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 OAP62321.1 - 0.00078 20.1 0.5 0.0029 18.3 0.1 2.1 2 1 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAP62321.1 - 0.0015 17.8 0.1 1.2 8.4 0.0 2.7 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Esterase_phd PF10503.9 OAP62321.1 - 0.0087 15.6 0.0 0.016 14.7 0.0 1.4 1 0 0 1 1 1 1 Esterase PHB depolymerase DLH PF01738.18 OAP62321.1 - 0.015 14.8 0.0 0.62 9.6 0.0 2.3 2 0 0 2 2 2 0 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 OAP62321.1 - 0.061 13.0 0.1 0.18 11.4 0.0 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold AXE1 PF05448.12 OAP62321.1 - 0.095 11.4 0.1 1.9 7.0 0.2 2.2 1 1 0 2 2 2 0 Acetyl xylan esterase (AXE1) Say1_Mug180 PF10340.9 OAP62321.1 - 0.12 11.2 0.0 0.15 10.9 0.0 1.1 1 0 0 1 1 1 0 Steryl acetyl hydrolase NGP1NT PF08153.12 OAP62322.1 - 1.8e-50 170.4 1.1 2.9e-50 169.8 1.1 1.3 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 OAP62322.1 - 1.3e-17 63.9 0.1 5.3e-14 52.3 0.0 2.9 2 1 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 OAP62322.1 - 1.2e-05 24.9 0.0 0.00017 21.1 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B Arf PF00025.21 OAP62322.1 - 0.00033 20.1 0.0 0.095 12.1 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OAP62322.1 - 0.00051 20.0 0.0 0.0014 18.6 0.0 1.7 1 1 0 1 1 1 1 RsgA GTPase Dynamin_N PF00350.23 OAP62322.1 - 0.0022 18.1 0.0 0.73 9.9 0.0 3.3 2 1 1 3 3 3 1 Dynamin family GTP_EFTU PF00009.27 OAP62322.1 - 0.0038 16.8 0.0 0.31 10.5 0.0 3.0 2 1 0 3 3 3 1 Elongation factor Tu GTP binding domain Metallophos PF00149.28 OAP62323.1 - 3.8e-13 50.4 0.3 6.3e-13 49.7 0.3 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OAP62323.1 - 0.13 12.4 0.0 14 5.8 0.0 2.4 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase superfamily domain Stk19 PF10494.9 OAP62325.1 - 9.1e-80 267.9 0.0 1.1e-79 267.6 0.0 1.1 1 0 0 1 1 1 1 Serine-threonine protein kinase 19 Glyco_transf_20 PF00982.21 OAP62326.1 - 1.2e-162 541.9 0.2 1.6e-162 541.5 0.2 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 OAP62326.1 - 8.9e-36 123.2 0.1 2.4e-35 121.8 0.0 1.7 2 0 0 2 2 2 1 Trehalose-phosphatase Hydrolase_3 PF08282.12 OAP62326.1 - 0.0099 15.6 0.0 0.77 9.4 0.0 2.5 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Glyco_transf_5 PF08323.11 OAP62326.1 - 0.07 12.8 0.4 0.19 11.4 0.2 1.7 2 0 0 2 2 2 0 Starch synthase catalytic domain GFO_IDH_MocA PF01408.22 OAP62327.1 - 3.7e-18 66.5 0.0 5.7e-18 65.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Cupin_2 PF07883.11 OAP62329.1 - 1.8e-09 37.2 0.0 2.8e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Cupin domain FAD_binding_4 PF01565.23 OAP62330.1 - 8.9e-31 106.5 2.5 1.2e-30 106.0 0.9 2.0 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 OAP62330.1 - 0.0049 16.9 0.1 0.011 15.9 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like Mo25 PF08569.11 OAP62330.1 - 0.2 11.0 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Mo25-like EthD PF07110.11 OAP62331.1 - 1.8e-13 51.4 0.0 2.3e-13 51.1 0.0 1.1 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 OAP62331.1 - 1.9e-05 25.1 0.2 2.3e-05 24.8 0.2 1.2 1 0 0 1 1 1 1 Methylmuconolactone methyl-isomerase DUF4990 PF16380.5 OAP62331.1 - 0.1 12.7 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function Abhydrolase_1 PF00561.20 OAP62332.1 - 3.7e-15 56.3 0.1 1.4e-12 47.8 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAP62332.1 - 8.1e-11 42.9 0.5 1.3e-10 42.3 0.5 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF1476 PF07345.11 OAP62332.1 - 0.057 13.8 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta Fungal_trans PF04082.18 OAP62333.1 - 3e-11 42.9 0.1 4.7e-11 42.2 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain NACHT PF05729.12 OAP62334.1 - 2.4e-08 34.1 0.1 1.2e-07 31.8 0.0 2.4 2 1 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 OAP62334.1 - 6.8e-05 23.3 0.9 0.00029 21.2 0.0 2.5 3 0 0 3 3 3 1 AAA ATPase domain AAA_33 PF13671.6 OAP62334.1 - 0.002 18.3 0.3 3.1 7.9 0.0 3.0 2 1 0 2 2 2 2 AAA domain 3H PF02829.14 OAP62334.1 - 0.0054 17.0 0.2 0.015 15.5 0.2 1.8 1 0 0 1 1 1 1 3H domain AAA_18 PF13238.6 OAP62334.1 - 0.011 16.2 0.0 0.049 14.2 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 OAP62334.1 - 0.062 13.6 0.0 0.23 11.7 0.0 2.0 1 0 0 1 1 1 0 AAA domain OTT_1508_deam PF14441.6 OAP62335.1 - 4.9e-19 68.1 0.2 1.1e-18 67.0 0.2 1.6 1 0 0 1 1 1 1 OTT_1508-like deaminase zf-MYND PF01753.18 OAP62335.1 - 0.077 13.1 10.4 0.17 12.0 10.4 1.6 1 0 0 1 1 1 0 MYND finger adh_short_C2 PF13561.6 OAP62336.1 - 1.5e-15 57.4 1.3 2.3e-13 50.3 1.3 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP62336.1 - 6.2e-13 48.7 0.4 8e-12 45.0 0.4 2.2 1 1 0 1 1 1 1 short chain dehydrogenase DNA_ligase_IV PF11411.8 OAP62336.1 - 0.24 11.5 0.6 0.9 9.7 0.2 2.2 2 0 0 2 2 2 0 DNA ligase IV 4HBT_3 PF13622.6 OAP62337.1 - 4e-50 171.4 0.1 4.5e-50 171.2 0.1 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Na_Ca_ex PF01699.24 OAP62338.1 - 2.5e-51 173.6 40.7 8.1e-28 97.3 18.8 3.1 3 0 0 3 3 3 2 Sodium/calcium exchanger protein Vpu PF00558.19 OAP62338.1 - 0.098 12.4 0.1 0.24 11.2 0.1 1.6 1 0 0 1 1 1 0 Vpu protein AMP-binding PF00501.28 OAP62339.1 - 3.5e-89 299.3 0.0 4.2e-89 299.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAP62339.1 - 2.4e-13 50.9 0.3 5.2e-13 49.8 0.3 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Formyl_trans_N PF00551.19 OAP62340.1 - 5.4e-40 137.1 0.0 7.7e-40 136.6 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase MannoseP_isomer PF01050.18 OAP62340.1 - 0.055 13.4 0.1 0.084 12.8 0.1 1.2 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase C2 PF00168.30 OAP62341.1 - 6.3e-11 42.5 0.0 1.2e-10 41.6 0.0 1.4 1 0 0 1 1 1 1 C2 domain Sigma70_r1_2 PF00140.20 OAP62341.1 - 0.11 12.6 0.1 0.31 11.1 0.1 1.8 1 0 0 1 1 1 0 Sigma-70 factor, region 1.2 AAA PF00004.29 OAP62342.1 - 2e-12 47.6 0.0 4.1e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OAP62342.1 - 1e-10 42.3 0.4 4.5e-10 40.2 0.1 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 OAP62342.1 - 1.2e-09 38.6 0.0 3.4e-09 37.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain Cdc6_C PF09079.11 OAP62342.1 - 9.6e-07 28.7 0.0 4.1e-06 26.7 0.0 2.2 1 1 0 1 1 1 1 CDC6, C terminal winged helix domain AAA_5 PF07728.14 OAP62342.1 - 0.0004 20.4 0.0 0.0018 18.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 OAP62342.1 - 0.0032 17.0 0.0 0.0071 15.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_30 PF13604.6 OAP62342.1 - 0.0037 17.0 0.0 0.0069 16.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 OAP62342.1 - 0.014 15.3 0.1 0.035 14.0 0.1 1.7 1 1 0 1 1 1 0 NACHT domain AAA_19 PF13245.6 OAP62342.1 - 0.032 14.6 0.3 0.16 12.3 0.1 2.3 2 1 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 OAP62342.1 - 0.053 13.2 0.0 0.13 11.9 0.0 1.7 2 0 0 2 2 2 0 Sigma-54 interaction domain PIF1 PF05970.14 OAP62342.1 - 0.056 12.6 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 PIF1-like helicase AAA_14 PF13173.6 OAP62342.1 - 0.15 12.1 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 OAP62342.1 - 0.17 12.3 0.0 0.37 11.2 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_29 PF13555.6 OAP62342.1 - 0.17 11.6 0.1 0.4 10.5 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Thioredoxin_7 PF13899.6 OAP62343.1 - 9.8e-17 60.9 0.0 2.1e-16 59.9 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like UBA_4 PF14555.6 OAP62343.1 - 4.1e-09 36.1 0.0 1e-08 34.8 0.0 1.7 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 OAP62343.1 - 7e-08 32.6 0.0 2e-07 31.1 0.0 1.8 2 0 0 2 2 2 1 UBX domain UIM PF02809.20 OAP62343.1 - 0.013 15.4 2.2 0.013 15.4 2.2 2.4 2 0 0 2 2 2 0 Ubiquitin interaction motif Thioredoxin_2 PF13098.6 OAP62343.1 - 0.022 15.2 0.0 0.046 14.2 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like domain Suf PF05843.14 OAP62343.1 - 0.079 12.9 0.4 0.13 12.2 0.4 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Pkinase PF00069.25 OAP62344.1 - 1.6e-69 234.2 0.0 2.8e-69 233.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP62344.1 - 9e-52 175.9 0.0 1.5e-51 175.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAP62344.1 - 0.00027 19.9 0.0 0.00055 18.8 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 OAP62344.1 - 0.00083 18.8 0.0 0.076 12.3 0.0 2.3 2 0 0 2 2 2 2 Kinase-like ABC1 PF03109.16 OAP62344.1 - 0.0041 17.3 0.1 0.032 14.4 0.0 2.3 2 0 0 2 2 2 1 ABC1 family HTH_35 PF13693.6 OAP62344.1 - 0.071 13.2 0.4 0.16 12.0 0.4 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding DUF3074 PF11274.8 OAP62345.1 - 1.5e-44 152.2 0.0 2e-44 151.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) Peptidase_S8 PF00082.22 OAP62346.1 - 9.6e-45 153.1 0.1 1.8e-44 152.2 0.1 1.5 1 0 0 1 1 1 1 Subtilase family p450 PF00067.22 OAP62347.1 - 6.8e-62 209.7 0.0 8.8e-62 209.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 NAD_binding_2 PF03446.15 OAP62348.1 - 1.6e-32 112.8 0.0 2.2e-32 112.4 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 OAP62348.1 - 8e-21 74.5 0.0 1.4e-20 73.8 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 OAP62348.1 - 0.0037 17.8 0.0 0.012 16.1 0.0 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 OAP62348.1 - 0.027 13.9 0.0 0.044 13.1 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 OAP62348.1 - 0.066 12.8 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Shikimate_DH PF01488.20 OAP62348.1 - 0.11 12.6 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase CMD PF02627.20 OAP62349.1 - 1.5e-21 76.3 0.1 2.7e-21 75.4 0.1 1.4 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family TetR_C_31 PF17940.1 OAP62349.1 - 0.06 13.6 0.7 0.19 12.0 0.2 1.9 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Bestrophin PF01062.21 OAP62350.1 - 1.2e-36 126.6 0.1 2e-36 125.9 0.1 1.3 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel T6SS_VasE PF05936.12 OAP62350.1 - 0.017 13.9 0.0 0.038 12.7 0.0 1.6 2 0 0 2 2 2 0 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE Glyco_transf_25 PF01755.17 OAP62351.1 - 7.1e-13 48.9 0.0 2.2e-11 44.0 0.0 2.6 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) Gly_transf_sug PF04488.15 OAP62352.1 - 1.1e-13 51.6 0.0 2e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TPPK_C PF12555.8 OAP62352.1 - 0.22 11.6 1.0 0.43 10.7 1.0 1.4 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal Abhydrolase_1 PF00561.20 OAP62353.1 - 2.3e-19 70.1 0.0 4.4e-18 65.9 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAP62353.1 - 1.4e-16 60.5 0.0 3e-16 59.4 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OAP62353.1 - 1.6e-16 61.6 3.6 1.8e-16 61.4 3.6 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 OAP62353.1 - 0.00039 20.6 0.1 0.00062 19.9 0.1 1.4 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_4 PF08386.10 OAP62353.1 - 0.0038 17.3 0.1 1.4 9.0 0.1 2.3 2 0 0 2 2 2 2 TAP-like protein DUF1100 PF06500.11 OAP62353.1 - 0.13 11.0 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) DUF3176 PF11374.8 OAP62354.1 - 4.7e-29 100.7 1.5 4.7e-29 100.7 1.5 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF3176) MS_channel PF00924.18 OAP62355.1 - 3.8e-15 56.0 0.6 8.4e-15 54.9 0.6 1.6 1 0 0 1 1 1 1 Mechanosensitive ion channel E1-E2_ATPase PF00122.20 OAP62355.1 - 0.9 9.0 4.4 1.3 8.6 0.6 2.4 2 0 0 2 2 2 0 E1-E2 ATPase OppC_N PF12911.7 OAP62355.1 - 2.1 8.4 5.2 2.7 8.0 1.1 2.6 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C 4HBT PF03061.22 OAP62356.1 - 2.9e-08 34.0 0.0 4.3e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_2 PF13279.6 OAP62356.1 - 2.6e-05 24.7 0.0 3.4e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.17 OAP62356.1 - 0.0002 20.8 0.1 0.00028 20.2 0.1 1.2 1 0 0 1 1 1 1 Acyl-ACP thioesterase MaoC_dehydratas PF01575.19 OAP62357.1 - 0.17 11.4 0.5 1.6 8.3 0.0 2.2 2 0 0 2 2 2 0 MaoC like domain PIP5K PF01504.18 OAP62359.1 - 2e-36 125.6 0.3 1.4e-27 96.6 0.8 2.6 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 OAP62359.1 - 7.4e-30 104.0 0.0 1.3e-29 103.2 0.0 1.3 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.21 OAP62359.1 - 6.1e-14 51.9 8.8 1.4e-13 50.7 8.8 1.7 1 0 0 1 1 1 1 FYVE zinc finger DZR PF12773.7 OAP62359.1 - 0.64 10.1 6.2 0.5 10.4 3.9 2.1 2 0 0 2 2 2 0 Double zinc ribbon C1_1 PF00130.22 OAP62359.1 - 1.6 8.7 11.1 0.091 12.7 5.5 1.9 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) F-box PF00646.33 OAP62360.1 - 0.0037 17.1 2.2 0.0045 16.8 0.1 2.1 2 0 0 2 2 2 1 F-box domain TniQ PF06527.11 OAP62360.1 - 0.0092 16.7 1.7 0.027 15.2 0.7 2.0 2 0 0 2 2 2 1 TniQ FAD_binding_3 PF01494.19 OAP62361.1 - 2.6e-18 66.4 0.0 5.9e-18 65.2 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 OAP62361.1 - 5.9e-05 22.4 0.0 0.00013 21.3 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OAP62361.1 - 0.00019 20.6 0.0 0.00031 19.9 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 OAP62361.1 - 0.00063 19.1 0.0 0.0011 18.3 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 OAP62361.1 - 0.00088 18.9 0.1 0.004 16.8 0.2 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase SE PF08491.10 OAP62361.1 - 0.00098 18.3 0.0 0.0017 17.5 0.0 1.3 1 0 0 1 1 1 1 Squalene epoxidase NAD_binding_8 PF13450.6 OAP62361.1 - 0.0016 18.6 0.2 0.0049 17.1 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 OAP62361.1 - 0.0031 16.4 1.0 0.97 8.2 0.0 2.4 3 0 0 3 3 3 2 Tryptophan halogenase Pyr_redox PF00070.27 OAP62361.1 - 0.004 17.7 0.1 0.018 15.6 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAP62361.1 - 0.0047 15.7 0.1 0.0075 15.0 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.7 OAP62361.1 - 0.0056 16.1 1.5 0.072 12.4 0.8 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase 3HCDH_N PF02737.18 OAP62361.1 - 0.089 12.7 0.1 0.21 11.5 0.0 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 OAP62361.1 - 0.15 11.3 0.1 2.7 7.2 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 OAP62361.1 - 0.18 12.3 0.0 0.4 11.2 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding GFO_IDH_MocA PF01408.22 OAP62362.1 - 1.7e-18 67.6 0.3 2.5e-18 67.0 0.3 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 OAP62362.1 - 1.3e-13 51.0 0.0 2.8e-13 49.9 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Semialdhyde_dh PF01118.24 OAP62362.1 - 1.4e-06 28.8 0.3 3e-05 24.5 0.1 2.3 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 OAP62362.1 - 0.00074 19.6 0.1 0.0024 18.0 0.0 1.8 1 1 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus CoA_binding PF02629.19 OAP62362.1 - 0.033 14.9 1.1 0.046 14.4 0.1 1.7 2 0 0 2 2 2 0 CoA binding domain Amidohydro_2 PF04909.14 OAP62363.1 - 4.6e-28 98.8 2.6 9.2e-28 97.8 2.6 1.5 1 1 0 1 1 1 1 Amidohydrolase PS_Dcarbxylase PF02666.15 OAP62364.1 - 9.9e-56 188.5 0.0 1.6e-55 187.8 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.30 OAP62364.1 - 1e-36 125.3 0.0 2.1e-17 63.3 0.0 2.5 2 0 0 2 2 2 2 C2 domain YL1 PF05764.13 OAP62364.1 - 0.063 13.4 5.0 0.017 15.3 1.8 1.7 2 0 0 2 2 2 0 YL1 nuclear protein HhH-GPD PF00730.25 OAP62365.1 - 9.1e-07 29.3 0.0 1.6e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein DPBB_1 PF03330.18 OAP62366.1 - 2.4e-05 24.5 0.1 3.8e-05 23.9 0.1 1.3 1 0 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 OAP62366.1 - 0.021 14.6 0.1 0.03 14.2 0.1 1.2 1 0 0 1 1 1 0 Barwin family SHP PF03579.13 OAP62366.1 - 0.082 12.9 0.1 0.13 12.3 0.1 1.3 1 0 0 1 1 1 0 Small hydrophobic protein FAM70 PF14967.6 OAP62366.1 - 0.15 11.5 0.0 0.2 11.1 0.0 1.1 1 0 0 1 1 1 0 FAM70 protein Amidase PF01425.21 OAP62367.1 - 1.3e-72 245.2 1.4 2.3e-71 241.1 1.4 2.3 1 1 0 1 1 1 1 Amidase Fasciclin PF02469.22 OAP62368.1 - 2.3e-45 153.9 3.3 3.1e-27 95.3 1.1 2.2 2 0 0 2 2 2 2 Fasciclin domain NPR3 PF03666.13 OAP62369.1 - 9.7 4.8 11.5 21 3.8 11.5 1.5 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 TAF4 PF05236.14 OAP62370.1 - 0.00076 19.3 5.2 0.00091 19.1 5.2 1.1 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family Trypan_PARP PF05887.11 OAP62370.1 - 0.085 12.8 4.7 0.36 10.8 0.3 2.1 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) FAM176 PF14851.6 OAP62370.1 - 0.19 11.4 3.9 0.3 10.7 3.9 1.3 1 0 0 1 1 1 0 FAM176 family DUF3245 PF11595.8 OAP62370.1 - 0.22 12.0 6.4 0.33 11.4 6.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) Acetyltransf_1 PF00583.25 OAP62371.1 - 2.6e-11 43.8 0.0 3.8e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OAP62371.1 - 4.2e-07 29.9 0.1 6.1e-07 29.4 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAP62371.1 - 8.2e-07 28.9 0.1 1.5e-06 28.1 0.1 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 OAP62371.1 - 3e-05 24.4 0.0 5.3e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 OAP62371.1 - 0.0055 16.8 0.2 0.0088 16.1 0.2 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 OAP62371.1 - 0.086 12.3 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Putative acetyl-transferase adh_short_C2 PF13561.6 OAP62372.1 - 2.5e-42 145.0 0.0 4.3e-35 121.4 0.0 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP62372.1 - 8.2e-39 133.1 0.0 1e-38 132.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAP62372.1 - 3.3e-11 43.4 0.0 5.7e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAP62372.1 - 0.0022 17.5 0.1 0.033 13.6 0.1 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Pkinase PF00069.25 OAP62373.1 - 2.7e-10 40.1 0.0 4.7e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain HEAT PF02985.22 OAP62373.1 - 4.9e-08 32.6 1.8 0.28 11.5 0.0 5.6 5 0 0 5 5 5 2 HEAT repeat Pkinase_Tyr PF07714.17 OAP62373.1 - 1.7e-05 24.2 0.0 3e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Cnd1 PF12717.7 OAP62373.1 - 2.8e-05 24.2 0.1 0.00083 19.4 0.0 2.3 1 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 OAP62373.1 - 0.00053 20.3 0.3 0.024 15.0 0.1 3.3 2 1 2 4 4 4 2 HEAT repeats HEAT_EZ PF13513.6 OAP62373.1 - 0.0022 18.5 0.3 1.4 9.5 0.0 3.7 2 1 1 3 3 3 1 HEAT-like repeat Kinase-like PF14531.6 OAP62373.1 - 0.23 10.7 0.0 0.38 10.0 0.0 1.2 1 0 0 1 1 1 0 Kinase-like DUF1857 PF08982.11 OAP62375.1 - 4.4e-49 166.1 0.1 4.9e-49 166.0 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1857) Mnd1 PF03962.15 OAP62375.1 - 0.17 12.2 0.7 0.33 11.3 0.7 1.5 1 0 0 1 1 1 0 Mnd1 HTH domain Zn_clus PF00172.18 OAP62376.1 - 1.9e-05 24.7 10.5 1.9e-05 24.7 10.5 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 OAP62376.1 - 0.0012 17.7 0.4 0.0041 16.0 0.0 2.0 2 1 0 2 2 2 1 Fungal specific transcription factor domain SUR7 PF06687.12 OAP62377.1 - 1.9e-38 132.2 10.8 2.5e-38 131.9 10.8 1.1 1 0 0 1 1 1 1 SUR7/PalI family DUF973 PF06157.11 OAP62377.1 - 0.078 12.0 1.4 0.2 10.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF973) Meckelin PF09773.9 OAP62377.1 - 2.3 6.2 3.4 3.2 5.7 3.4 1.1 1 0 0 1 1 1 0 Meckelin (Transmembrane protein 67) TPR_12 PF13424.6 OAP62379.1 - 5.9e-34 116.2 6.0 6.6e-14 52.0 0.0 5.6 1 1 3 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.6 OAP62379.1 - 8.6e-27 92.2 6.5 7.3e-09 35.2 0.0 6.3 6 0 0 6 6 6 4 Tetratricopeptide repeat NACHT PF05729.12 OAP62379.1 - 3.1e-11 43.5 0.0 1.1e-10 41.7 0.0 1.9 1 0 0 1 1 1 1 NACHT domain TPR_7 PF13176.6 OAP62379.1 - 5e-11 41.8 4.2 0.044 13.8 0.0 5.9 5 0 0 5 5 5 3 Tetratricopeptide repeat AAA_16 PF13191.6 OAP62379.1 - 1e-07 32.5 0.3 3.5e-07 30.8 0.0 2.1 2 0 0 2 2 1 1 AAA ATPase domain TPR_1 PF00515.28 OAP62379.1 - 1.8e-06 27.5 0.1 0.25 11.3 0.0 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 OAP62379.1 - 3.6e-05 23.6 0.0 1.4 9.3 0.1 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 OAP62379.1 - 5.7e-05 22.9 0.3 9.4 6.6 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat AAA_22 PF13401.6 OAP62379.1 - 6.9e-05 23.1 0.0 0.00042 20.6 0.0 2.5 2 1 1 3 3 2 1 AAA domain NB-ARC PF00931.22 OAP62379.1 - 0.00087 18.6 0.0 0.0017 17.6 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain TPR_MalT PF17874.1 OAP62379.1 - 0.0032 16.9 8.4 0.0088 15.5 0.7 2.6 1 1 1 2 2 2 1 MalT-like TPR region TPR_14 PF13428.6 OAP62379.1 - 0.0044 17.7 0.2 3.6 8.6 0.0 4.1 2 1 1 3 3 3 1 Tetratricopeptide repeat RNA_helicase PF00910.22 OAP62379.1 - 0.0075 16.6 0.0 0.022 15.2 0.0 1.8 1 0 0 1 1 1 1 RNA helicase AAA_19 PF13245.6 OAP62379.1 - 0.0087 16.4 0.0 0.025 14.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 OAP62379.1 - 0.022 14.7 0.0 0.053 13.4 0.0 1.6 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_14 PF13173.6 OAP62379.1 - 0.024 14.7 0.0 0.19 11.7 0.0 2.4 1 1 0 1 1 1 0 AAA domain ResIII PF04851.15 OAP62379.1 - 0.055 13.5 0.0 0.15 12.1 0.0 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_30 PF13604.6 OAP62379.1 - 0.058 13.1 0.0 0.24 11.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 OAP62379.1 - 0.059 13.2 0.0 0.16 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 OAP62379.1 - 0.067 13.7 0.4 0.61 10.6 0.0 2.7 2 1 0 2 2 2 0 ABC transporter Rad17 PF03215.15 OAP62379.1 - 0.1 12.5 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain AAA PF00004.29 OAP62379.1 - 0.14 12.6 0.0 0.38 11.2 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) vWA-TerF-like PF10138.9 OAP62381.1 - 1.4e-06 28.6 0.0 2.2e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA PF00092.28 OAP62381.1 - 7e-05 23.1 0.0 0.00016 22.0 0.0 1.6 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 OAP62381.1 - 0.013 14.9 0.0 0.044 13.2 0.0 1.8 1 1 0 1 1 1 0 VWA domain containing CoxE-like protein UPF0270 PF06794.12 OAP62381.1 - 0.026 14.6 0.1 0.079 13.0 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0270) VWA_2 PF13519.6 OAP62381.1 - 0.055 14.1 0.2 0.3 11.8 0.0 2.4 3 1 0 3 3 3 0 von Willebrand factor type A domain Ank_2 PF12796.7 OAP62382.1 - 8.9e-48 160.8 0.0 1.9e-15 57.2 0.0 4.5 3 1 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAP62382.1 - 2.6e-35 120.3 3.3 3.7e-09 36.9 0.0 5.4 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 OAP62382.1 - 1.6e-31 107.3 2.0 1.3e-07 31.7 0.0 6.8 7 0 0 7 7 6 5 Ankyrin repeat Ank_3 PF13606.6 OAP62382.1 - 4e-28 94.3 1.0 0.00024 21.3 0.0 7.1 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 OAP62382.1 - 6e-21 74.2 5.6 8.7e-06 25.9 0.0 6.7 2 1 5 7 7 7 6 Ankyrin repeats (many copies) DUF676 PF05057.14 OAP62382.1 - 0.00065 19.3 0.0 0.00096 18.7 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 OAP62382.1 - 0.0047 17.6 4.1 0.3 11.7 3.5 2.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 OAP62382.1 - 0.012 15.5 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAP62382.1 - 0.016 14.4 0.0 0.028 13.7 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 LIDHydrolase PF10230.9 OAP62382.1 - 0.053 13.1 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase SIR2_2 PF13289.6 OAP62382.1 - 0.061 13.4 0.0 1.9 8.6 0.0 2.5 2 0 0 2 2 2 0 SIR2-like domain PGAP1 PF07819.13 OAP62382.1 - 0.083 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein MmgE_PrpD PF03972.14 OAP62383.1 - 8.8e-64 215.7 7.8 1e-63 215.4 7.8 1.1 1 0 0 1 1 1 1 MmgE/PrpD family AA_permease PF00324.21 OAP62384.1 - 2.8e-90 303.2 45.4 6.7e-90 302.0 45.4 1.5 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAP62384.1 - 2.3e-24 86.0 46.0 3e-24 85.6 46.0 1.1 1 0 0 1 1 1 1 Amino acid permease Acetyltransf_10 PF13673.7 OAP62385.1 - 0.00091 19.2 0.0 0.0019 18.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAP62385.1 - 0.0016 18.7 0.0 0.0021 18.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 OAP62385.1 - 0.0065 16.4 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein TauD PF02668.16 OAP62386.1 - 8e-37 127.5 0.1 1.3e-36 126.8 0.1 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family ECH_1 PF00378.20 OAP62387.1 - 3.4e-37 128.1 0.1 4.5e-37 127.7 0.1 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAP62387.1 - 6.5e-19 68.6 0.0 8.2e-19 68.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase BACON PF13004.7 OAP62387.1 - 0.076 13.0 0.2 0.14 12.2 0.2 1.4 1 0 0 1 1 1 0 Putative binding domain, N-terminal His_Phos_2 PF00328.22 OAP62388.1 - 2.5e-26 92.9 0.0 3.2e-26 92.6 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) p450 PF00067.22 OAP62390.1 - 4.4e-69 233.4 0.0 5.5e-69 233.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.25 OAP62391.1 - 3.2e-34 118.1 0.8 4.2e-33 114.5 0.8 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP62391.1 - 4.3e-25 88.6 0.2 2.4e-24 86.2 0.2 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP62391.1 - 8e-15 55.2 0.8 2.3e-14 53.7 0.3 1.8 2 0 0 2 2 2 1 KR domain Eno-Rase_NADH_b PF12242.8 OAP62391.1 - 0.0014 18.4 0.2 0.045 13.5 0.1 2.6 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Polysacc_synt_2 PF02719.15 OAP62391.1 - 0.023 13.8 0.1 0.032 13.4 0.1 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF656 PF04920.12 OAP62391.1 - 0.044 13.7 0.0 0.085 12.8 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF656) NmrA PF05368.13 OAP62392.1 - 2.3e-14 53.5 0.0 3.5e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 OAP62392.1 - 2.2e-06 27.9 0.0 4.2e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 OAP62392.1 - 4.1e-06 26.8 0.0 7.2e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Aldo_ket_red PF00248.21 OAP62393.1 - 1.2e-42 146.1 0.1 2.4e-41 141.9 0.1 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family SLX9 PF15341.6 OAP62394.1 - 2.5e-33 115.3 4.5 2.5e-33 115.3 4.5 1.4 2 0 0 2 2 2 1 Ribosome biogenesis protein SLX9 EthD PF07110.11 OAP62395.1 - 0.0014 19.7 0.0 0.0032 18.6 0.0 1.5 1 1 0 1 1 1 1 EthD domain DUF1445 PF07286.12 OAP62396.1 - 6.8e-60 201.1 0.0 9e-60 200.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1445) Cellulase PF00150.18 OAP62397.1 - 1.5e-28 100.0 1.0 2.5e-28 99.3 1.0 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Sugar_tr PF00083.24 OAP62398.1 - 3.3e-76 257.0 13.8 3.8e-76 256.8 13.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP62398.1 - 2.5e-28 99.1 30.6 6.3e-26 91.1 17.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 OAP62398.1 - 4.3e-07 28.9 13.8 1.3e-06 27.2 3.5 2.4 2 0 0 2 2 2 2 MFS/sugar transport protein TRI12 PF06609.13 OAP62398.1 - 6.1e-07 28.2 2.2 1.3e-06 27.1 2.2 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 OAP62398.1 - 3.2 5.9 8.7 0.25 9.6 0.2 2.6 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family DUF2235 PF09994.9 OAP62399.1 - 2.7e-33 115.6 0.0 4e-33 115.0 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) TauD PF02668.16 OAP62400.1 - 1.1e-45 156.6 0.0 1.2e-45 156.4 0.0 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Pkinase PF00069.25 OAP62401.1 - 5.1e-27 94.9 0.0 6.1e-16 58.6 0.0 2.4 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAP62401.1 - 4.5e-09 36.0 0.1 3e-05 23.4 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase RIO1 PF01163.22 OAP62401.1 - 0.048 13.3 0.0 0.093 12.3 0.0 1.4 1 0 0 1 1 1 0 RIO1 family PBP PF01161.20 OAP62402.1 - 5e-16 59.2 0.0 6.5e-16 58.8 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Zn_clus PF00172.18 OAP62403.1 - 1.2e-07 31.7 10.9 2.3e-07 30.8 10.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 OAP62404.1 - 9.7e-12 44.4 0.2 2.3e-11 43.2 0.2 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Fer2_2 PF01799.20 OAP62404.1 - 0.11 12.5 0.2 0.29 11.2 0.2 1.7 1 0 0 1 1 1 0 [2Fe-2S] binding domain ANAPC4_WD40 PF12894.7 OAP62405.1 - 1.4e-11 44.5 0.4 0.21 11.9 0.0 7.2 3 2 4 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OAP62405.1 - 2.2e-07 31.5 11.8 0.25 12.3 0.1 8.9 10 1 0 10 10 10 3 WD domain, G-beta repeat Ge1_WD40 PF16529.5 OAP62405.1 - 0.002 17.2 0.0 0.026 13.5 0.0 2.6 2 0 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 OAP62405.1 - 0.039 13.9 0.9 0.84 9.7 0.0 3.2 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Rad4 PF03835.15 OAP62406.1 - 1.2e-15 57.5 4.5 2.2e-15 56.6 4.5 1.4 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Transglut_core PF01841.19 OAP62406.1 - 1.2e-13 51.5 1.3 2.8e-13 50.3 1.3 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily YdjO PF14169.6 OAP62406.1 - 0.038 13.7 0.8 7.5 6.4 0.0 2.5 2 0 0 2 2 2 0 Cold-inducible protein YdjO AA_permease PF00324.21 OAP62407.1 - 1.3e-125 419.7 42.2 2.4e-113 379.3 24.5 2.0 1 1 1 2 2 2 2 Amino acid permease AA_permease_2 PF13520.6 OAP62407.1 - 1.2e-26 93.5 38.3 2e-26 92.8 25.8 2.1 1 1 1 2 2 2 2 Amino acid permease Internalin_N PF12354.8 OAP62407.1 - 0.062 13.4 1.4 0.24 11.5 0.0 2.7 2 1 0 2 2 2 0 Bacterial adhesion/invasion protein N terminal MBOAT_2 PF13813.6 OAP62410.1 - 1.7e-18 66.7 0.6 5.1e-18 65.1 0.6 1.9 1 1 0 1 1 1 1 Membrane bound O-acyl transferase family peroxidase PF00141.23 OAP62411.1 - 1.5e-50 172.0 0.0 2.6e-50 171.2 0.0 1.4 1 0 0 1 1 1 1 Peroxidase AIF-MLS PF14962.6 OAP62411.1 - 0.025 14.6 1.5 0.038 14.0 1.5 1.2 1 0 0 1 1 1 0 Mitochondria Localisation Sequence MFS_1 PF07690.16 OAP62413.1 - 1.7e-37 129.2 27.5 2.6e-37 128.6 27.5 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Peptidase_A8 PF01252.18 OAP62413.1 - 7.9 6.7 14.9 1.9 8.7 1.2 3.7 2 2 1 4 4 4 0 Signal peptidase (SPase) II COesterase PF00135.28 OAP62414.1 - 3.4e-76 257.2 0.0 5.3e-76 256.5 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAP62414.1 - 7.2e-08 32.5 1.2 8.5e-07 29.0 1.2 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OAP62414.1 - 0.0038 16.7 0.1 0.0066 15.9 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family AMP-binding PF00501.28 OAP62415.1 - 3.1e-68 230.3 0.0 5.3e-68 229.5 0.0 1.3 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAP62415.1 - 1.8e-13 51.3 0.1 3.6e-13 50.3 0.1 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PI-PLC-X PF00388.19 OAP62416.1 - 4.7e-49 165.7 0.0 7.3e-49 165.1 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 OAP62416.1 - 6.4e-38 129.6 0.0 1.4e-37 128.6 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain BolA PF01722.18 OAP62417.1 - 4.7e-29 100.5 0.2 5.7e-29 100.2 0.2 1.1 1 0 0 1 1 1 1 BolA-like protein Cofilin_ADF PF00241.20 OAP62417.1 - 0.073 12.9 0.0 0.079 12.8 0.0 1.2 1 0 0 1 1 1 0 Cofilin/tropomyosin-type actin-binding protein Syntaxin PF00804.25 OAP62418.1 - 1.7e-21 76.8 10.9 4.6e-21 75.4 10.9 1.7 1 1 0 1 1 1 1 Syntaxin SNARE PF05739.19 OAP62418.1 - 6e-11 42.2 2.2 8.6e-11 41.7 0.4 2.2 2 0 0 2 2 2 1 SNARE domain Use1 PF09753.9 OAP62418.1 - 3.5e-05 23.7 4.1 5.2e-05 23.1 4.1 1.2 1 0 0 1 1 1 1 Membrane fusion protein Use1 HHH_2 PF12826.7 OAP62418.1 - 0.0097 16.0 0.3 0.058 13.5 0.3 2.2 1 1 1 2 2 2 1 Helix-hairpin-helix motif Syntaxin_2 PF14523.6 OAP62418.1 - 0.013 15.8 4.7 0.05 14.0 0.5 2.5 2 1 0 2 2 2 0 Syntaxin-like protein DUF1634 PF07843.11 OAP62418.1 - 0.019 15.0 0.3 0.034 14.2 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1634) DUF4094 PF13334.6 OAP62418.1 - 0.029 14.8 2.3 0.15 12.5 0.6 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4094) Tweety PF04906.13 OAP62418.1 - 0.063 11.9 1.6 0.12 11.0 1.6 1.4 1 0 0 1 1 1 0 Tweety Laminin_II PF06009.12 OAP62418.1 - 0.51 10.4 7.0 1.8 8.6 1.8 2.4 2 1 0 2 2 2 0 Laminin Domain II RIFIN PF02009.16 OAP62418.1 - 2.6 7.9 7.5 4.3 7.1 7.1 1.6 1 1 1 2 2 2 0 Rifin Spectrin PF00435.21 OAP62418.1 - 8.2 7.0 11.7 5.4 7.6 1.3 3.5 2 2 2 4 4 4 0 Spectrin repeat NAPRTase PF04095.16 OAP62419.1 - 1.2e-59 201.8 0.0 1.9e-32 112.8 0.1 2.2 2 0 0 2 2 2 2 Nicotinate phosphoribosyltransferase (NAPRTase) family NAPRTase_N PF17767.1 OAP62419.1 - 1.3e-37 128.9 0.5 2.1e-37 128.3 0.5 1.3 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain TSC22 PF01166.18 OAP62419.1 - 0.17 12.2 0.0 0.41 11.0 0.1 1.6 2 0 0 2 2 2 0 TSC-22/dip/bun family ADH_N PF08240.12 OAP62420.1 - 1.9e-11 43.8 0.3 1.3e-09 37.9 0.1 2.7 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAP62420.1 - 1.1e-07 31.9 0.3 1.8e-07 31.2 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 OAP62420.1 - 0.024 14.5 0.0 0.049 13.5 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase Glyco_hydro_16 PF00722.21 OAP62421.1 - 3.7e-42 143.8 3.0 6.3e-42 143.0 3.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 CD34_antigen PF06365.12 OAP62421.1 - 0.0011 18.6 0.0 0.0021 17.7 0.0 1.4 1 0 0 1 1 1 1 CD34/Podocalyxin family Mid2 PF04478.12 OAP62421.1 - 0.0063 16.4 0.1 0.012 15.4 0.1 1.4 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor DUF2207 PF09972.9 OAP62421.1 - 0.0094 14.8 0.0 0.015 14.1 0.0 1.3 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) Protocadherin PF08374.11 OAP62421.1 - 0.039 13.9 0.0 0.064 13.2 0.0 1.4 1 0 0 1 1 1 0 Protocadherin Peptidase_M56 PF05569.11 OAP62421.1 - 0.077 12.2 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 BlaR1 peptidase M56 TMEM52 PF14979.6 OAP62421.1 - 0.092 12.7 0.1 0.16 11.9 0.1 1.4 1 0 0 1 1 1 0 Transmembrane 52 Saw1 PF11561.8 OAP62423.1 - 0.016 14.8 0.1 0.14 11.7 0.1 2.0 2 0 0 2 2 2 0 Single strand annealing-weakened 1 Glyco_hydro_79C PF16862.5 OAP62424.1 - 2.5e-20 73.3 0.3 2.5e-20 73.3 0.3 2.4 2 0 0 2 2 2 1 Glycosyl hydrolase family 79 C-terminal beta domain DUF1180 PF06679.12 OAP62424.1 - 2.7 8.4 6.7 4.8 7.6 6.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Cation_efflux PF01545.21 OAP62425.1 - 3.1e-24 85.8 11.8 4e-24 85.4 11.8 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 OAP62425.1 - 9.8e-07 28.8 0.0 1.9e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Sugar_tr PF00083.24 OAP62426.1 - 2.1e-43 148.8 2.0 2.4e-43 148.6 2.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP62426.1 - 2.1e-08 33.5 5.2 2.5e-08 33.2 5.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily CbtB PF09489.10 OAP62426.1 - 0.48 10.6 1.7 1.6 8.9 0.0 2.6 3 0 0 3 3 3 0 Probable cobalt transporter subunit (CbtB) GFO_IDH_MocA PF01408.22 OAP62427.1 - 9.2e-22 78.1 0.0 1.7e-21 77.3 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 OAP62427.1 - 0.00032 20.7 0.0 0.00076 19.5 0.0 1.6 1 1 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Pkinase PF00069.25 OAP62428.1 - 4.6e-41 140.9 0.0 2e-40 138.8 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP62428.1 - 3.7e-26 92.0 0.0 5.6e-26 91.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OAP62428.1 - 0.035 14.0 0.1 0.2 11.5 0.1 2.2 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 OAP62428.1 - 0.036 13.4 0.0 0.062 12.6 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 OAP62428.1 - 0.039 13.3 0.0 0.068 12.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ANTH PF07651.16 OAP62429.1 - 6.5e-61 205.8 0.1 8.8e-61 205.3 0.1 1.2 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.20 OAP62429.1 - 2.6e-06 27.5 0.0 4.5e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 ENTH domain TPP_enzyme_N PF02776.18 OAP62430.1 - 4e-31 107.9 0.3 6e-31 107.3 0.3 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 OAP62430.1 - 3.9e-16 59.2 0.1 4.3e-15 55.8 0.0 2.6 2 1 1 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 OAP62430.1 - 7.5e-16 58.1 0.0 5e-15 55.5 0.0 2.2 1 1 1 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Filament PF00038.21 OAP62432.1 - 0.056 13.0 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Intermediate filament protein DUF3819 PF12842.7 OAP62433.1 - 0.029 14.3 0.5 0.039 13.9 0.5 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3819) Peptidase_S64 PF08192.11 OAP62436.1 - 0.3 9.5 1.1 0.48 8.8 1.1 1.3 1 0 0 1 1 1 0 Peptidase family S64 HSP20 PF00011.21 OAP62437.1 - 6.3e-18 64.8 0.5 1.5e-11 44.3 0.0 2.3 2 0 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 OAP62437.1 - 2.1e-05 24.0 0.0 0.087 12.4 0.0 2.3 2 0 0 2 2 2 2 HSP20-like domain found in ArsA Peroxin-3 PF04882.12 OAP62437.1 - 0.3 10.0 9.8 0.43 9.5 9.8 1.1 1 0 0 1 1 1 0 Peroxin-3 Presenilin PF01080.17 OAP62437.1 - 1 8.0 4.1 1.3 7.7 4.1 1.1 1 0 0 1 1 1 0 Presenilin Abhydrolase_1 PF00561.20 OAP62438.1 - 5.8e-27 94.9 0.1 1.3e-26 93.8 0.1 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAP62438.1 - 9.3e-24 84.0 0.4 4.2e-16 59.0 0.1 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OAP62438.1 - 5.2e-20 73.0 0.1 6.8e-20 72.6 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 OAP62438.1 - 1.2e-07 31.4 0.5 0.0098 15.4 0.0 2.5 2 1 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_5 PF12695.7 OAP62438.1 - 6.4e-07 29.3 0.0 0.00011 22.0 0.0 2.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 OAP62438.1 - 0.00014 22.0 0.0 0.0026 17.8 0.0 2.5 3 0 0 3 3 3 1 TAP-like protein Peptidase_S15 PF02129.18 OAP62438.1 - 0.00081 19.1 0.1 0.32 10.5 0.0 2.3 2 0 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_2 PF02230.16 OAP62438.1 - 0.001 18.9 0.0 0.02 14.7 0.0 2.4 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Ser_hydrolase PF06821.13 OAP62438.1 - 0.003 17.4 0.0 0.037 13.9 0.0 2.1 2 0 0 2 2 2 1 Serine hydrolase Ndr PF03096.14 OAP62438.1 - 0.0037 16.0 0.0 0.025 13.3 0.0 1.9 2 0 0 2 2 2 1 Ndr family Chlorophyllase2 PF12740.7 OAP62438.1 - 0.0095 14.9 0.0 0.027 13.4 0.0 1.6 1 1 0 1 1 1 1 Chlorophyllase enzyme FSH1 PF03959.13 OAP62438.1 - 0.015 15.0 0.0 0.023 14.3 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) MTD PF01993.18 OAP62438.1 - 0.028 13.8 0.0 0.041 13.2 0.0 1.2 1 0 0 1 1 1 0 methylene-5,6,7,8-tetrahydromethanopterin dehydrogenase UPF0227 PF05728.12 OAP62438.1 - 0.044 13.7 0.0 0.59 10.1 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) DUF915 PF06028.11 OAP62438.1 - 0.045 13.1 0.1 0.17 11.2 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) BAAT_C PF08840.11 OAP62438.1 - 0.055 13.4 0.1 0.21 11.5 0.1 1.9 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal PAF-AH_p_II PF03403.13 OAP62438.1 - 0.057 11.9 0.1 10 4.5 0.0 2.7 2 1 1 3 3 3 0 Platelet-activating factor acetylhydrolase, isoform II PGAP1 PF07819.13 OAP62438.1 - 0.06 13.1 0.0 0.8 9.4 0.0 2.0 2 0 0 2 2 2 0 PGAP1-like protein DLH PF01738.18 OAP62438.1 - 0.1 12.1 0.1 0.57 9.7 0.0 2.1 2 1 1 3 3 3 0 Dienelactone hydrolase family AXE1 PF05448.12 OAP62438.1 - 0.17 10.5 0.3 0.72 8.5 0.1 1.9 1 1 1 2 2 2 0 Acetyl xylan esterase (AXE1) GST_N_3 PF13417.6 OAP62440.1 - 8.6e-17 61.3 0.0 1.4e-16 60.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OAP62440.1 - 4.1e-15 55.8 0.0 7.1e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 OAP62440.1 - 1.1e-12 48.1 0.0 2.3e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_5 PF16865.5 OAP62440.1 - 0.00013 22.4 0.0 0.00023 21.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 OAP62440.1 - 0.00063 19.9 0.0 0.0016 18.6 0.0 1.7 2 0 0 2 2 2 1 Glutaredoxin GST_C PF00043.25 OAP62440.1 - 0.0053 16.9 0.1 0.0095 16.1 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain WW PF00397.26 OAP62441.1 - 1.1e-11 44.6 0.6 2.4e-11 43.5 0.6 1.7 1 0 0 1 1 1 1 WW domain DUF4585 PF15232.6 OAP62441.1 - 0.0044 17.0 0.0 0.034 14.2 0.0 2.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4585) PhoD PF09423.10 OAP62441.1 - 0.027 13.5 0.1 0.2 10.7 0.2 2.0 2 0 0 2 2 2 0 PhoD-like phosphatase Fungal_trans_2 PF11951.8 OAP62442.1 - 1.5e-12 47.0 0.0 2.4e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain RIFIN PF02009.16 OAP62443.1 - 0.7 9.7 7.3 0.85 9.5 7.3 1.1 1 0 0 1 1 1 0 Rifin MFS_1 PF07690.16 OAP62448.1 - 6.5e-08 31.9 56.0 6.5e-08 31.9 56.0 3.7 1 1 0 2 2 2 1 Major Facilitator Superfamily DUF1769 PF08588.10 OAP62449.1 - 2.4e-28 98.1 0.1 6.6e-28 96.7 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) DUF874 PF05917.11 OAP62449.1 - 0.12 11.3 7.8 0.17 10.9 7.8 1.1 1 0 0 1 1 1 0 Helicobacter pylori protein of unknown function (DUF874) ARGLU PF15346.6 OAP62449.1 - 0.72 9.7 18.3 1.2 9.0 18.3 1.3 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 CALCOCO1 PF07888.11 OAP62450.1 - 0.0028 16.6 6.4 0.0028 16.6 6.4 3.0 2 1 0 2 2 2 1 Calcium binding and coiled-coil domain (CALCOCO1) like Tic22 PF04278.12 OAP62450.1 - 0.59 9.5 3.5 4.8 6.5 0.2 2.8 3 0 0 3 3 3 0 Tic22-like family FAM184 PF15665.5 OAP62450.1 - 8.4 6.1 50.6 1.4 8.7 35.1 3.1 2 1 1 3 3 3 0 Family with sequence similarity 184, A and B RhoGAP PF00620.27 OAP62451.1 - 3e-15 56.4 0.0 9.5e-15 54.7 0.0 1.9 1 0 0 1 1 1 1 RhoGAP domain DEP PF00610.21 OAP62451.1 - 1.2e-10 41.3 0.0 2.6e-10 40.2 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) FCH PF00611.23 OAP62451.1 - 1.1e-07 32.0 0.0 3.5e-07 30.4 0.0 2.0 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain BAR PF03114.18 OAP62451.1 - 0.17 11.5 3.3 0.14 11.8 0.8 2.0 2 0 0 2 2 2 0 BAR domain PK PF00224.21 OAP62452.1 - 1.7e-170 566.5 5.2 2.1e-170 566.2 5.2 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 OAP62452.1 - 3.3e-37 127.3 0.0 1e-36 125.7 0.0 1.9 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 OAP62452.1 - 0.00021 20.5 0.3 0.00063 18.9 0.1 1.7 1 1 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.25 OAP62452.1 - 0.0018 17.3 0.0 0.021 13.8 0.0 2.2 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain DUF3506 PF12014.8 OAP62453.1 - 1.7e-53 180.4 0.0 2.7e-53 179.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3506) F-box-like PF12937.7 OAP62453.1 - 1.3e-09 37.7 3.8 2.7e-09 36.8 3.8 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAP62453.1 - 1.3e-08 34.5 3.2 1.3e-08 34.5 3.2 1.6 2 0 0 2 2 2 1 F-box domain F-box_4 PF15966.5 OAP62453.1 - 0.00029 20.7 0.1 0.00056 19.8 0.1 1.4 1 0 0 1 1 1 1 F-box Elongin_A PF06881.11 OAP62453.1 - 0.0012 19.3 0.0 0.0067 16.9 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase II transcription factor SIII (Elongin) subunit A FAT PF02259.23 OAP62454.1 - 0.011 15.0 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 0 FAT domain Nup54_C PF18437.1 OAP62454.1 - 0.17 11.8 0.2 0.34 10.8 0.2 1.5 1 0 0 1 1 1 0 Nup54 C-terminal interacting domain Epimerase PF01370.21 OAP62456.1 - 4e-07 29.8 0.0 5.3e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAP62456.1 - 0.00014 21.4 0.1 0.0017 17.8 0.0 2.0 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 OAP62456.1 - 0.00061 19.7 0.0 0.001 19.0 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 OAP62456.1 - 0.072 12.2 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain KR PF08659.10 OAP62456.1 - 0.085 12.8 0.0 0.18 11.7 0.0 1.5 1 1 0 1 1 1 0 KR domain Glyco_hydro_17 PF00332.18 OAP62457.1 - 8.9e-05 22.2 0.3 0.00016 21.4 0.3 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 Glyco_hydro_42 PF02449.15 OAP62457.1 - 0.023 14.0 0.0 0.033 13.5 0.0 1.2 1 0 0 1 1 1 0 Beta-galactosidase APG6_N PF17675.1 OAP62458.1 - 0.0048 17.4 6.0 0.013 16.0 6.0 1.7 1 0 0 1 1 1 1 Apg6 coiled-coil region MPS2 PF17060.5 OAP62458.1 - 0.018 14.4 1.8 0.033 13.5 1.8 1.3 1 0 0 1 1 1 0 Monopolar spindle protein 2 Iso_dh PF00180.20 OAP62459.1 - 6.5e-98 328.1 0.0 7.7e-97 324.6 0.0 1.9 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase CHASE3 PF05227.13 OAP62459.1 - 0.018 14.9 0.7 0.03 14.2 0.7 1.3 1 0 0 1 1 1 0 CHASE3 domain ATP-synt_S1 PF05827.12 OAP62460.1 - 1.4e-05 24.9 0.0 2.2e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) ThiF PF00899.21 OAP62461.1 - 1.8e-52 178.1 0.0 2.8e-52 177.5 0.0 1.2 1 0 0 1 1 1 1 ThiF family NAD_binding_7 PF13241.6 OAP62461.1 - 0.042 14.3 0.1 0.39 11.2 0.1 2.2 1 1 0 1 1 1 0 Putative NAD(P)-binding Rhodanese PF00581.20 OAP62461.1 - 0.15 12.6 0.0 2.8 8.5 0.0 2.5 1 1 0 1 1 1 0 Rhodanese-like domain NAD_Gly3P_dh_N PF01210.23 OAP62462.1 - 1.1e-44 152.2 0.0 5.8e-44 149.8 0.0 2.0 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 OAP62462.1 - 6.4e-44 149.7 0.0 1.1e-43 148.9 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus Metallophos PF00149.28 OAP62463.1 - 2.4e-13 51.1 0.0 3.7e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OAP62463.1 - 2.8e-09 37.4 0.2 1.4e-07 31.9 0.2 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Transp_inhibit PF18791.1 OAP62463.1 - 0.056 12.9 0.0 0.17 11.4 0.0 1.8 1 0 0 1 1 1 0 Transport inhibitor response 1 protein domain Acyl-CoA_dh_1 PF00441.24 OAP62465.1 - 4.9e-37 127.5 1.7 7.9e-37 126.8 1.7 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.28 OAP62465.1 - 2.3e-16 59.7 0.0 5.1e-16 58.6 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.19 OAP62465.1 - 1.9e-15 56.8 0.9 3.6e-15 55.9 0.9 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 OAP62465.1 - 2.5e-09 37.8 0.0 6.3e-09 36.5 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 OAP62465.1 - 2.7e-07 30.9 0.0 4.9e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain PH_14 PF17787.1 OAP62465.1 - 0.07 13.0 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 PH domain NMO PF03060.15 OAP62466.1 - 6e-53 180.4 2.4 9.9e-52 176.4 2.4 1.9 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 OAP62466.1 - 3.1e-12 46.1 0.0 3.2e-10 39.5 0.0 2.2 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 OAP62466.1 - 0.015 14.3 1.0 0.025 13.6 1.0 1.3 1 0 0 1 1 1 0 FMN-dependent dehydrogenase adh_short PF00106.25 OAP62467.1 - 6.2e-36 123.7 0.0 8.1e-36 123.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP62467.1 - 2.5e-25 89.4 0.0 3.1e-25 89.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 3HCDH_N PF02737.18 OAP62467.1 - 0.0016 18.3 0.1 0.0024 17.8 0.1 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain KR PF08659.10 OAP62467.1 - 0.0034 17.3 0.1 0.007 16.3 0.1 1.5 1 1 0 1 1 1 1 KR domain F420_oxidored PF03807.17 OAP62467.1 - 0.059 14.0 0.2 0.14 12.7 0.1 1.7 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Polysacc_synt_2 PF02719.15 OAP62467.1 - 0.15 11.1 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Shikimate_DH PF01488.20 OAP62467.1 - 0.2 11.7 0.0 0.31 11.1 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase AMP-binding PF00501.28 OAP62468.1 - 1.2e-95 320.6 0.0 1.5e-95 320.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAP62468.1 - 1.5e-15 57.9 0.7 3.6e-15 56.7 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DSBA PF01323.20 OAP62469.1 - 4.9e-16 59.1 0.0 5.6e-16 58.9 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Peptidase_M19 PF01244.21 OAP62470.1 - 1.9e-89 300.0 0.0 2.3e-89 299.7 0.0 1.1 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Cellulase PF00150.18 OAP62471.1 - 2.2e-27 96.2 0.1 2.7e-27 95.9 0.1 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_trans_2_3 PF13632.6 OAP62472.1 - 4.3e-18 66.0 0.7 4.3e-18 66.0 0.7 1.7 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 OAP62472.1 - 2.3e-05 24.4 0.0 5.2e-05 23.2 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase like family 2 hDGE_amylase PF14701.6 OAP62475.1 - 9.3e-171 568.7 0.0 1.3e-170 568.3 0.0 1.2 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain GDE_C PF06202.14 OAP62475.1 - 4.6e-119 397.8 0.0 7.8e-119 397.0 0.0 1.3 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase DAHP_synth_1 PF00793.20 OAP62475.1 - 4.5e-102 340.6 0.0 8.2e-101 336.5 0.0 2.1 2 0 0 2 2 2 1 DAHP synthetase I family hGDE_central PF14702.6 OAP62475.1 - 1.7e-85 286.8 0.0 2.9e-85 286.0 0.0 1.4 1 0 0 1 1 1 1 Central domain of human glycogen debranching enzyme hGDE_N PF14699.6 OAP62475.1 - 7.8e-31 106.1 0.0 2.4e-30 104.5 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.24 OAP62475.1 - 0.032 13.8 0.0 0.06 12.9 0.0 1.3 1 0 0 1 1 1 0 Alpha amylase, catalytic domain DUF3602 PF12223.8 OAP62476.1 - 1e-16 61.3 11.5 5.3e-14 52.6 2.2 2.8 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) Velvet PF11754.8 OAP62477.1 - 7.1e-74 248.9 0.0 1.2e-73 248.1 0.0 1.3 1 0 0 1 1 1 1 Velvet factor Sec10 PF07393.11 OAP62478.1 - 6.2e-127 424.9 0.7 9.3e-127 424.3 0.7 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 F-box PF00646.33 OAP62478.1 - 4.8e-06 26.3 0.2 1e-05 25.3 0.2 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 OAP62478.1 - 2e-05 24.4 0.1 5.6e-05 23.0 0.1 1.8 1 0 0 1 1 1 1 F-box-like CAP PF00188.26 OAP62480.1 - 2.2e-16 60.8 6.1 1.4e-15 58.2 6.1 2.0 1 1 0 1 1 1 1 Cysteine-rich secretory protein family NAD_binding_10 PF13460.6 OAP62481.1 - 0.068 13.1 0.0 0.43 10.5 0.0 2.0 2 0 0 2 2 2 0 NAD(P)H-binding FMN_dh PF01070.18 OAP62482.1 - 4.3e-108 361.4 0.0 5.4e-108 361.1 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 OAP62482.1 - 4.8e-17 61.9 0.0 8.9e-17 61.0 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 OAP62482.1 - 0.00049 19.3 0.0 0.00081 18.6 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 OAP62482.1 - 0.00067 18.8 0.5 0.007 15.4 0.1 2.0 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 OAP62482.1 - 0.002 17.6 0.0 0.003 17.0 0.0 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase RabGAP-TBC PF00566.18 OAP62483.1 - 1.2e-23 83.9 0.0 2.2e-23 83.1 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SBE2 PF17076.5 OAP62483.1 - 5.3e-07 28.3 1.4 5.3e-07 28.3 1.4 2.7 2 1 1 3 3 3 2 SBE2, cell-wall formation Upf2 PF04050.14 OAP62483.1 - 0.066 13.9 0.7 0.18 12.5 0.7 1.7 1 0 0 1 1 1 0 Up-frameshift suppressor 2 Telomerase_RBD PF12009.8 OAP62484.1 - 5.6e-47 159.2 0.1 1.8e-46 157.6 0.1 1.9 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.27 OAP62484.1 - 4.1e-11 42.8 0.1 7.9e-07 28.8 0.0 2.6 3 0 0 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) NHL PF01436.21 OAP62484.1 - 0.043 13.9 0.4 0.5 10.5 0.1 2.4 2 0 0 2 2 2 0 NHL repeat RhoGEF PF00621.20 OAP62485.1 - 1.3e-33 116.7 0.1 2.8e-33 115.7 0.1 1.6 1 0 0 1 1 1 1 RhoGEF domain Peptidase_C48 PF02902.19 OAP62486.1 - 6.3e-16 58.9 0.7 2.1e-15 57.2 0.7 1.8 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DUF4951 PF16309.5 OAP62486.1 - 0.00072 19.5 0.1 0.0014 18.6 0.1 1.4 1 0 0 1 1 1 1 Domian of unknown function (DUF4951) MFS_1 PF07690.16 OAP62487.1 - 1.3e-21 77.0 20.4 1.5e-21 76.7 20.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.16 OAP62488.1 - 2.2e-06 26.9 0.0 2.7e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Syntaxin PF00804.25 OAP62489.1 - 0.52 9.9 5.3 1 9.0 5.3 1.3 1 0 0 1 1 1 0 Syntaxin DUF1690 PF07956.11 OAP62489.1 - 1.6 9.1 5.8 4.6 7.7 5.8 1.7 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) zf-C3HC4_3 PF13920.6 OAP62490.1 - 9.3e-07 28.6 9.1 9.3e-07 28.6 9.1 3.4 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OAP62490.1 - 4.8 7.1 20.7 0.069 13.0 10.9 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) SWIB PF02201.18 OAP62491.1 - 1.6e-28 98.3 0.2 3e-28 97.5 0.2 1.5 1 0 0 1 1 1 1 SWIB/MDM2 domain DEK_C PF08766.11 OAP62491.1 - 6.6e-12 45.2 0.4 1.4e-11 44.1 0.4 1.5 1 0 0 1 1 1 1 DEK C terminal domain eIF2A PF08662.11 OAP62492.1 - 7.2e-39 133.7 4.9 3.2e-34 118.5 1.7 3.9 3 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.22 OAP62492.1 - 5.6e-07 29.3 0.0 1.3e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.32 OAP62492.1 - 2.6 9.1 4.3 71 4.5 0.1 4.3 5 0 0 5 5 5 0 WD domain, G-beta repeat Cep57_MT_bd PF06657.13 OAP62493.1 - 0.0012 19.2 1.3 0.0027 18.1 0.0 2.3 2 0 0 2 2 2 1 Centrosome microtubule-binding domain of Cep57 SH3BP5 PF05276.14 OAP62493.1 - 0.11 12.3 6.3 0.26 11.1 1.0 2.3 2 0 0 2 2 2 0 SH3 domain-binding protein 5 (SH3BP5) Ribosomal_L5_C PF00673.21 OAP62495.1 - 5.5e-22 77.8 0.0 8.1e-22 77.2 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 OAP62495.1 - 2.6e-20 72.5 0.0 8.9e-20 70.8 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L5 LSM PF01423.22 OAP62496.1 - 7.1e-20 70.5 0.0 1.2e-19 69.7 0.0 1.3 1 0 0 1 1 1 1 LSM domain Nop25 PF09805.9 OAP62497.1 - 1.4e-40 139.0 11.3 1.4e-40 139.0 11.3 3.1 2 1 1 3 3 3 1 Nucleolar protein 12 (25kDa) DUF4504 PF14953.6 OAP62497.1 - 0.04 13.3 0.0 0.065 12.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4504) Tropomyosin_1 PF12718.7 OAP62498.1 - 6.6e-53 178.7 38.7 8.2e-53 178.4 38.7 1.1 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.20 OAP62498.1 - 2.4e-08 33.7 36.0 0.0013 18.2 21.0 2.6 1 1 1 2 2 2 2 Tropomyosin KLRAQ PF10205.9 OAP62498.1 - 0.00056 20.1 13.6 0.00056 20.1 13.6 2.7 1 1 1 2 2 2 1 Predicted coiled-coil domain-containing protein Taxilin PF09728.9 OAP62498.1 - 0.0016 17.7 32.8 0.078 12.1 16.7 2.0 1 1 1 2 2 2 2 Myosin-like coiled-coil protein DUF4200 PF13863.6 OAP62498.1 - 0.0017 18.7 39.4 0.11 12.9 13.4 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF4200) Spc7 PF08317.11 OAP62498.1 - 0.0034 16.3 37.7 0.016 14.1 16.6 2.0 1 1 1 2 2 2 2 Spc7 kinetochore protein Myosin_tail_1 PF01576.19 OAP62498.1 - 0.011 13.6 33.0 0.013 13.4 33.0 1.0 1 0 0 1 1 1 0 Myosin tail DUF3450 PF11932.8 OAP62498.1 - 0.02 14.2 33.6 0.29 10.4 16.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Transketolase_N PF00456.21 OAP62498.1 - 0.021 13.8 7.5 0.028 13.4 7.5 1.0 1 0 0 1 1 1 0 Transketolase, thiamine diphosphate binding domain DUF1664 PF07889.12 OAP62498.1 - 0.021 14.8 17.2 0.077 13.0 3.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Lebercilin PF15619.6 OAP62498.1 - 0.022 14.4 37.3 1.3 8.6 20.0 2.1 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease GAS PF13851.6 OAP62498.1 - 0.026 13.9 35.4 25 4.1 33.8 2.4 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding CASP_C PF08172.12 OAP62498.1 - 0.031 13.6 2.6 0.031 13.6 2.6 2.2 1 1 1 2 2 2 0 CASP C terminal BLOC1_2 PF10046.9 OAP62498.1 - 0.049 13.9 1.7 0.049 13.9 1.7 3.3 1 1 3 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF724 PF05266.14 OAP62498.1 - 0.053 13.4 28.5 0.042 13.7 11.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF724) ERM PF00769.19 OAP62498.1 - 0.076 12.8 42.4 0.07 12.9 20.6 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Cast PF10174.9 OAP62498.1 - 0.12 10.6 28.3 0.18 10.0 28.3 1.3 1 1 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone DUF3584 PF12128.8 OAP62498.1 - 0.14 9.6 33.6 0.5 7.8 33.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) Leu_zip PF15294.6 OAP62498.1 - 0.14 11.6 25.9 0.18 11.3 25.9 1.1 1 0 0 1 1 1 0 Leucine zipper ATG16 PF08614.11 OAP62498.1 - 0.14 12.3 36.9 1.2 9.4 17.1 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) TACC_C PF05010.14 OAP62498.1 - 0.15 11.9 28.6 0.69 9.7 17.3 2.2 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal FUSC PF04632.12 OAP62498.1 - 0.15 10.5 10.9 0.19 10.2 10.9 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Jnk-SapK_ap_N PF09744.9 OAP62498.1 - 0.19 11.9 37.1 0.099 12.9 12.9 2.2 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Filament PF00038.21 OAP62498.1 - 0.19 11.2 30.0 2.2 7.8 30.0 1.9 1 1 0 1 1 1 0 Intermediate filament protein ADIP PF11559.8 OAP62498.1 - 0.2 11.7 36.1 0.39 10.8 12.1 3.0 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding TMF_DNA_bd PF12329.8 OAP62498.1 - 0.21 11.6 40.9 0.57 10.2 16.1 3.4 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding EzrA PF06160.12 OAP62498.1 - 0.22 9.6 26.1 0.063 11.5 8.3 2.1 1 1 0 2 2 2 0 Septation ring formation regulator, EzrA CENP-F_leu_zip PF10473.9 OAP62498.1 - 0.23 11.5 36.0 0.09 12.8 6.9 2.8 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 BST2 PF16716.5 OAP62498.1 - 0.23 12.1 33.6 1.3 9.7 14.4 3.4 1 1 2 3 3 3 0 Bone marrow stromal antigen 2 FlaC_arch PF05377.11 OAP62498.1 - 0.25 11.8 23.1 1.1 9.7 2.4 4.5 1 1 4 5 5 5 0 Flagella accessory protein C (FlaC) TMF_TATA_bd PF12325.8 OAP62498.1 - 0.26 11.5 29.1 0.78 10.0 15.9 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Laminin_II PF06009.12 OAP62498.1 - 0.26 11.3 22.1 0.031 14.3 8.1 2.3 1 1 1 2 2 2 0 Laminin Domain II Dynamitin PF04912.14 OAP62498.1 - 0.26 10.5 28.1 1.1 8.5 28.1 2.0 1 1 0 1 1 1 0 Dynamitin HMMR_N PF15905.5 OAP62498.1 - 0.27 10.6 34.4 0.43 10.0 34.4 1.3 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Fez1 PF06818.15 OAP62498.1 - 0.32 11.4 28.8 0.52 10.7 28.8 1.4 1 0 0 1 1 1 0 Fez1 HOOK PF05622.12 OAP62498.1 - 0.49 8.5 32.2 0.89 7.6 32.2 1.5 1 1 0 1 1 1 0 HOOK protein CALCOCO1 PF07888.11 OAP62498.1 - 0.64 8.8 34.3 0.22 10.3 11.4 2.2 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF5595 PF18077.1 OAP62498.1 - 0.67 10.1 21.1 1.1 9.4 4.9 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF5595) FAM76 PF16046.5 OAP62498.1 - 0.68 9.2 26.1 5.7 6.2 26.1 1.9 1 1 0 1 1 1 0 FAM76 protein DUF3138 PF11336.8 OAP62498.1 - 0.75 8.3 6.7 1 7.9 6.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) MAD PF05557.13 OAP62498.1 - 0.83 7.9 33.0 2.1 6.6 33.0 1.6 1 1 0 1 1 1 0 Mitotic checkpoint protein NPV_P10 PF05531.12 OAP62498.1 - 1.2 9.6 14.3 4.9 7.7 0.1 3.3 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein WXG100 PF06013.12 OAP62498.1 - 1.3 9.3 21.3 0.36 11.1 0.9 3.6 2 1 0 2 2 1 0 Proteins of 100 residues with WXG DUF812 PF05667.11 OAP62498.1 - 1.4 7.7 32.3 1.9 7.3 32.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) BRE1 PF08647.11 OAP62498.1 - 1.6 8.9 37.3 3.6 7.7 7.8 3.0 1 1 2 3 3 3 0 BRE1 E3 ubiquitin ligase KASH_CCD PF14662.6 OAP62498.1 - 1.6 8.5 35.4 6.7 6.5 33.9 2.5 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Uso1_p115_C PF04871.13 OAP62498.1 - 1.6 9.1 40.5 11 6.4 18.7 2.2 1 1 1 2 2 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region TPR_MLP1_2 PF07926.12 OAP62498.1 - 1.7 8.7 43.7 4.9 7.2 6.4 3.3 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein PI3K_P85_iSH2 PF16454.5 OAP62498.1 - 1.7 8.2 29.3 4.3 6.9 22.5 2.5 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain AAA_13 PF13166.6 OAP62498.1 - 1.7 7.2 27.4 4.6 5.8 27.4 1.7 1 1 0 1 1 1 0 AAA domain Nup88 PF10168.9 OAP62498.1 - 2 6.1 26.4 3.5 5.3 26.4 1.3 1 1 0 1 1 1 0 Nuclear pore component DUF4201 PF13870.6 OAP62498.1 - 2 8.1 30.3 5.7 6.6 12.3 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) Syntaxin_2 PF14523.6 OAP62498.1 - 2.1 8.8 20.1 0.32 11.4 12.5 2.2 1 1 1 2 2 2 0 Syntaxin-like protein bZIP_1 PF00170.21 OAP62498.1 - 2.1 8.5 33.5 4.1 7.6 1.0 4.6 2 1 1 4 4 4 0 bZIP transcription factor APG6_N PF17675.1 OAP62498.1 - 2.3 8.7 45.0 7.3 7.1 24.2 2.3 1 1 1 2 2 2 0 Apg6 coiled-coil region Rab5-bind PF09311.11 OAP62498.1 - 2.4 7.5 30.1 0.82 9.0 16.1 2.1 1 1 1 2 2 2 0 Rabaptin-like protein HAUS6_N PF14661.6 OAP62498.1 - 2.5 7.6 27.5 0.21 11.2 8.7 2.5 1 1 1 2 2 1 0 HAUS augmin-like complex subunit 6 N-terminus Cep57_MT_bd PF06657.13 OAP62498.1 - 2.9 8.4 24.1 1.4 9.5 4.3 3.9 1 1 3 4 4 4 0 Centrosome microtubule-binding domain of Cep57 Phage_GP20 PF06810.11 OAP62498.1 - 2.9 7.7 30.5 6 6.7 11.6 3.1 1 1 2 3 3 3 0 Phage minor structural protein GP20 V_ATPase_I PF01496.19 OAP62498.1 - 3.1 5.6 24.5 0.099 10.5 10.6 2.0 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family WDCP PF15390.6 OAP62498.1 - 3.2 6.0 16.7 3.5 5.9 16.7 1.0 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family DUF4472 PF14739.6 OAP62498.1 - 3.8 8.3 30.5 4.4 8.1 14.3 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4472) SlyX PF04102.12 OAP62498.1 - 4.7 7.9 27.5 6.1 7.5 3.1 3.9 1 1 3 4 4 4 0 SlyX Peptidase_S64 PF08192.11 OAP62498.1 - 6.3 5.2 15.2 7.5 4.9 15.2 1.0 1 0 0 1 1 1 0 Peptidase family S64 FapA PF03961.13 OAP62498.1 - 6.5 5.2 27.9 0.59 8.7 11.9 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A DUF4795 PF16043.5 OAP62498.1 - 6.6 6.3 29.5 1.6e+03 -1.5 29.5 2.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) KxDL PF10241.9 OAP62498.1 - 7 7.0 21.8 0.16 12.2 1.4 3.6 1 1 3 4 4 3 0 Uncharacterized conserved protein TMPIT PF07851.13 OAP62498.1 - 7.2 5.8 25.1 2 7.6 4.1 2.0 1 1 1 2 2 2 0 TMPIT-like protein Mod_r PF07200.13 OAP62498.1 - 7.7 6.6 33.6 4.9 7.2 4.9 2.1 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF465 PF04325.13 OAP62498.1 - 7.9 6.6 16.4 3.5 7.7 0.2 4.3 3 1 1 4 4 4 0 Protein of unknown function (DUF465) SHE3 PF17078.5 OAP62498.1 - 8.5 6.0 26.9 25 4.5 24.8 2.2 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 Seryl_tRNA_N PF02403.22 OAP62498.1 - 9.6 6.5 34.0 8.1 6.7 1.4 3.1 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF4407 PF14362.6 OAP62498.1 - 9.6 5.5 30.5 1.3e+02 1.7 30.6 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Fib_alpha PF08702.10 OAP62498.1 - 10 6.3 21.3 5.1 7.3 12.2 2.5 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Aminotran_4 PF01063.19 OAP62500.1 - 2.3e-25 89.8 0.0 2.9e-25 89.4 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV Evr1_Alr PF04777.13 OAP62501.1 - 4.3e-24 84.9 0.2 1e-23 83.7 0.1 1.7 1 1 0 1 1 1 1 Erv1 / Alr family APOBEC4 PF18775.1 OAP62501.1 - 0.091 12.9 0.2 0.17 12.1 0.2 1.4 1 0 0 1 1 1 0 APOBEC4 SNAD4 PF18750.1 OAP62501.1 - 0.11 12.6 0.0 0.23 11.6 0.0 1.5 1 1 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 DUF4131 PF13567.6 OAP62501.1 - 0.13 11.9 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) FAD_SOX PF18371.1 OAP62501.1 - 0.15 12.5 0.0 0.26 11.7 0.0 1.4 1 0 0 1 1 1 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase Methyltransf_2 PF00891.18 OAP62502.1 - 7.9e-23 80.8 0.0 1.2e-22 80.3 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 OAP62502.1 - 6.3e-06 26.8 0.0 0.00014 22.5 0.0 2.7 3 0 0 3 3 3 1 Methyltransferase domain MTS PF05175.14 OAP62502.1 - 3.8e-05 23.3 0.0 0.00016 21.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_31 PF13847.6 OAP62502.1 - 0.00046 20.0 0.0 0.00089 19.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAP62502.1 - 0.00052 20.7 0.0 0.0014 19.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 OAP62502.1 - 0.0012 18.6 0.0 0.0021 17.8 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_32 PF13679.6 OAP62502.1 - 0.07 13.1 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.17 OAP62502.1 - 0.11 11.9 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Aldo_ket_red PF00248.21 OAP62503.1 - 3.4e-73 246.4 0.2 3.8e-73 246.2 0.2 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DEAD PF00270.29 OAP62504.1 - 3.1e-48 163.9 0.0 9.3e-48 162.3 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAP62504.1 - 1.2e-31 109.4 0.0 2.5e-31 108.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAP62504.1 - 0.00055 20.0 0.0 0.00089 19.3 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 OAP62504.1 - 0.053 12.8 0.0 0.09 12.1 0.0 1.2 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Pro_isomerase PF00160.21 OAP62505.1 - 1e-49 168.8 0.2 1.3e-49 168.5 0.2 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ribosomal_S13 PF00416.22 OAP62506.1 - 6.1e-18 65.5 0.2 1.9e-15 57.4 0.2 2.2 1 1 0 1 1 1 1 Ribosomal protein S13/S18 AA_permease PF00324.21 OAP62507.1 - 6.7e-56 189.8 31.7 8.5e-56 189.5 31.7 1.1 1 0 0 1 1 1 1 Amino acid permease SLC12 PF03522.15 OAP62507.1 - 3.3e-23 82.4 7.2 1.8e-10 40.4 0.0 4.1 4 0 0 4 4 4 3 Solute carrier family 12 Jagunal PF07086.12 OAP62507.1 - 0.015 15.4 0.3 0.015 15.4 0.3 2.1 2 1 0 2 2 2 0 Jagunal, ER re-organisation during oogenesis DUF5562 PF17717.1 OAP62507.1 - 0.33 10.9 2.0 0.4 10.6 0.2 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5562) CDC45 PF02724.14 OAP62507.1 - 6.3 5.0 13.9 9.3 4.4 13.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Aa_trans PF01490.18 OAP62508.1 - 2e-83 280.4 30.7 2.4e-83 280.1 30.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Adeno_GP19K PF04881.13 OAP62508.1 - 0.13 12.3 1.7 0.17 11.9 0.3 1.9 2 0 0 2 2 2 0 Adenovirus GP19K YpmT PF17431.2 OAP62508.1 - 1.3 9.1 4.7 1.8 8.6 0.9 2.9 2 0 0 2 2 2 0 Uncharacterized YmpT-like tRNA-synt_1g PF09334.11 OAP62509.1 - 1.1e-87 294.4 0.5 6.8e-86 288.5 0.5 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 OAP62509.1 - 1.2e-16 60.1 4.0 8.3e-09 34.2 0.1 3.4 1 1 2 3 3 3 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 OAP62509.1 - 1.8e-10 40.7 0.0 1.7e-05 24.4 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Ish1 PF10281.9 OAP62510.1 - 0.00015 22.0 0.4 0.00023 21.4 0.4 1.3 1 0 0 1 1 1 1 Putative stress-responsive nuclear envelope protein SAP PF02037.27 OAP62510.1 - 0.013 15.2 0.0 0.023 14.5 0.0 1.4 1 0 0 1 1 1 0 SAP domain HATPase_c PF02518.26 OAP62511.1 - 3.7e-19 69.3 0.0 7.1e-19 68.4 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 OAP62511.1 - 1.4e-17 63.9 0.1 6.6e-17 61.7 0.1 2.2 1 1 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 OAP62511.1 - 3.6e-06 26.9 0.1 8.7e-06 25.7 0.1 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain AMP-binding PF00501.28 OAP62512.1 - 2.4e-72 243.9 0.0 3.1e-72 243.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAP62512.1 - 3.3e-11 44.0 0.2 8.7e-11 42.7 0.2 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PFOR_II PF17147.4 OAP62512.1 - 0.093 13.0 0.0 0.22 11.8 0.0 1.6 1 0 0 1 1 1 0 Pyruvate:ferredoxin oxidoreductase core domain II G_glu_transpept PF01019.21 OAP62513.1 - 2.4e-164 547.9 0.5 2.7e-164 547.7 0.5 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase MFS_1 PF07690.16 OAP62514.1 - 1.9e-49 168.5 34.3 1.9e-49 168.5 34.3 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAP62514.1 - 4.4e-10 39.0 9.3 4.4e-10 39.0 9.3 2.7 1 1 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 OAP62514.1 - 1.2e-05 24.8 4.9 1.2e-05 24.8 4.9 2.5 3 0 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB TRI12 PF06609.13 OAP62514.1 - 7.7e-05 21.3 1.7 0.00014 20.5 1.7 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Abhydrolase_2 PF02230.16 OAP62515.1 - 1.5e-36 126.3 0.0 9.3e-36 123.7 0.0 1.9 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase FSH1 PF03959.13 OAP62515.1 - 7e-06 25.8 0.0 1.1e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 OAP62515.1 - 0.00014 22.5 0.0 0.00022 21.9 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAP62515.1 - 0.0049 16.2 0.0 1.4 8.1 0.0 2.4 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OAP62515.1 - 0.0073 16.0 0.0 0.044 13.4 0.0 2.0 1 1 1 2 2 2 1 alpha/beta hydrolase fold Cutinase PF01083.22 OAP62515.1 - 0.014 15.3 0.0 0.023 14.7 0.0 1.3 1 0 0 1 1 1 0 Cutinase Abhydrolase_3 PF07859.13 OAP62515.1 - 0.016 15.1 0.0 0.045 13.6 0.0 1.7 1 1 1 2 2 2 0 alpha/beta hydrolase fold AXE1 PF05448.12 OAP62515.1 - 0.024 13.3 0.0 0.047 12.3 0.0 1.4 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) RNB PF00773.19 OAP62516.1 - 4.7e-99 331.8 0.1 7e-99 331.2 0.1 1.2 1 0 0 1 1 1 1 RNB domain Rrp44_CSD1 PF17216.3 OAP62516.1 - 1e-32 112.9 0.0 2.4e-32 111.7 0.0 1.7 1 0 0 1 1 1 1 Rrp44-like cold shock domain Rrp44_S1 PF17215.3 OAP62516.1 - 6.9e-26 90.0 1.0 1.5e-25 89.0 1.0 1.5 1 0 0 1 1 1 1 S1 domain OB_Dis3 PF17849.1 OAP62516.1 - 1e-20 73.5 0.0 2.8e-20 72.1 0.0 1.8 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) PIN_4 PF13638.6 OAP62516.1 - 7.4e-11 42.5 0.1 2.2e-10 41.0 0.1 1.8 1 0 0 1 1 1 1 PIN domain CSD2 PF17876.1 OAP62516.1 - 5.2e-06 26.5 0.0 0.00041 20.4 0.0 2.8 2 0 0 2 2 2 1 Cold shock domain PIN_9 PF18477.1 OAP62516.1 - 0.48 10.8 3.2 14 6.0 0.0 3.5 3 1 1 4 4 4 0 PIN like domain Methyltransf_4 PF02390.17 OAP62517.1 - 1.9e-47 160.9 0.0 2.9e-47 160.3 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 OAP62517.1 - 0.028 15.1 0.0 0.063 14.0 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 OAP62517.1 - 0.15 11.6 0.0 0.45 10.1 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase small domain AA_permease_2 PF13520.6 OAP62518.1 - 6e-55 186.8 52.1 7.2e-55 186.5 52.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAP62518.1 - 3.7e-20 72.0 41.6 4.9e-20 71.6 41.6 1.1 1 0 0 1 1 1 1 Amino acid permease PDR_CDR PF06422.12 OAP62518.1 - 2.5 8.1 5.0 1.9 8.4 0.3 3.1 3 0 0 3 3 3 0 CDR ABC transporter TadE PF07811.12 OAP62518.1 - 7.8 6.9 10.1 7.4 6.9 1.0 3.8 3 0 0 3 3 3 0 TadE-like protein Cation_efflux PF01545.21 OAP62520.1 - 6.3e-23 81.5 5.0 8.7e-23 81.1 5.0 1.2 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 OAP62520.1 - 0.00087 19.4 0.0 0.002 18.2 0.0 1.6 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Csm2_III-A PF03750.13 OAP62520.1 - 0.045 14.6 0.7 1 10.2 0.3 2.5 2 0 0 2 2 2 0 Csm2 Type III-A zf-RING_2 PF13639.6 OAP62521.1 - 1.5e-08 34.8 7.3 1.5e-08 34.8 7.3 2.0 2 0 0 2 2 2 1 Ring finger domain zf-ANAPC11 PF12861.7 OAP62521.1 - 3.5e-06 27.0 1.5 3.5e-06 27.0 1.5 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 OAP62521.1 - 2.1e-05 24.4 4.0 5.1e-05 23.2 4.0 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_4 PF14570.6 OAP62521.1 - 8.3e-05 22.3 6.6 0.00018 21.3 6.6 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 OAP62521.1 - 0.0018 18.4 8.0 0.0018 18.4 8.0 1.8 2 1 0 2 2 2 1 FANCL C-terminal domain zf-C3HC4_3 PF13920.6 OAP62521.1 - 0.0025 17.7 4.7 0.0025 17.7 4.7 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAP62521.1 - 0.0043 17.0 7.1 0.0089 16.0 7.1 1.6 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_1 PF14446.6 OAP62521.1 - 0.0045 16.9 4.1 0.0045 16.9 4.1 2.0 1 1 0 1 1 1 1 Prokaryotic RING finger family 1 zf-C3HC4_4 PF15227.6 OAP62521.1 - 0.015 15.4 6.3 0.086 13.0 6.3 2.1 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 OAP62521.1 - 0.017 15.4 8.6 0.017 15.4 8.6 2.2 2 1 1 3 3 3 0 RING-H2 zinc finger domain Usp PF00582.26 OAP62521.1 - 0.12 12.9 0.0 0.23 12.0 0.0 1.4 1 0 0 1 1 1 0 Universal stress protein family Prok-RING_4 PF14447.6 OAP62521.1 - 0.33 10.8 5.1 8.4 6.3 1.9 2.6 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 OAP62521.1 - 0.57 9.8 10.0 2.2 8.0 10.2 1.9 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type zf-C3HC4 PF00097.25 OAP62521.1 - 0.71 9.8 13.4 0.046 13.6 7.1 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OAP62521.1 - 3.1 7.7 13.4 0.17 11.8 6.7 2.3 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) RasGEF PF00617.19 OAP62522.1 - 3.7e-50 170.6 0.4 9.1e-50 169.3 0.4 1.7 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 OAP62522.1 - 2.4e-12 47.0 0.0 1.3e-11 44.7 0.0 2.3 2 0 0 2 2 2 1 RasGEF N-terminal motif SH3_9 PF14604.6 OAP62522.1 - 4.9e-08 32.7 0.0 1.1e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 OAP62522.1 - 3.4e-06 26.6 0.0 7.6e-06 25.4 0.0 1.7 1 0 0 1 1 1 1 SH3 domain I_LWEQ PF01608.17 OAP62522.1 - 0.024 14.9 1.1 0.75 10.0 0.4 3.2 3 1 0 3 3 3 0 I/LWEQ domain SPX PF03105.19 OAP62522.1 - 8.6 6.2 16.0 8.9 6.1 1.0 2.5 2 0 0 2 2 2 0 SPX domain Hexapep PF00132.24 OAP62523.1 - 3.4e-11 42.4 6.7 2.1e-06 27.2 1.5 2.8 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 OAP62523.1 - 6.6e-09 35.4 4.7 0.00023 20.8 0.9 2.4 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Zn_clus PF00172.18 OAP62523.1 - 2.4e-07 30.8 9.9 2.4e-07 30.8 9.9 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_11 PF13414.6 OAP62523.1 - 0.011 15.4 0.0 0.021 14.5 0.0 1.4 1 0 0 1 1 1 0 TPR repeat HATPase_c_3 PF13589.6 OAP62524.1 - 1.3e-11 44.4 0.0 2.6e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.11 OAP62524.1 - 2.7e-11 43.4 0.0 4.4e-10 39.5 0.0 2.3 2 0 0 2 2 2 1 MutL C terminal dimerisation domain HATPase_c PF02518.26 OAP62524.1 - 8e-05 23.1 0.1 0.00017 22.0 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Med5 PF08689.10 OAP62525.1 - 2.2e-40 138.5 0.0 2.8e-39 134.8 0.0 2.0 2 0 0 2 2 2 2 Mediator complex subunit Med5 Fungal_trans_2 PF11951.8 OAP62526.1 - 0.0018 17.2 0.2 0.0043 15.9 0.1 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP62526.1 - 0.013 15.6 3.4 0.027 14.6 3.4 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Lactamase_B PF00753.27 OAP62527.1 - 0.00027 21.0 0.7 0.0031 17.6 0.1 2.4 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OAP62527.1 - 0.057 12.9 0.1 0.12 11.9 0.1 1.5 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Fungal_trans_2 PF11951.8 OAP62529.1 - 4.7e-05 22.4 1.1 0.0055 15.6 0.1 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Abhydrolase_1 PF00561.20 OAP62530.1 - 0.00095 18.9 0.1 0.0021 17.7 0.1 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold LIP PF03583.14 OAP62530.1 - 0.0011 18.4 0.0 0.0027 17.1 0.0 1.6 2 0 0 2 2 2 1 Secretory lipase DUF1100 PF06500.11 OAP62530.1 - 0.018 13.8 0.0 0.038 12.8 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1100) Peptidase_S9 PF00326.21 OAP62530.1 - 0.026 14.0 0.2 0.9 9.0 0.1 2.3 1 1 0 2 2 2 0 Prolyl oligopeptidase family BAAT_C PF08840.11 OAP62530.1 - 0.19 11.6 0.0 0.96 9.3 0.0 1.9 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal ABC_tran PF00005.27 OAP62533.1 - 3.2e-38 131.4 0.0 1.3e-17 64.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 OAP62533.1 - 1.6e-17 64.1 23.4 2.3e-11 43.9 3.1 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.6 OAP62533.1 - 1.5e-07 31.6 3.1 0.12 12.2 0.0 4.1 3 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 OAP62533.1 - 2.5e-07 30.3 0.1 0.0043 16.8 0.0 3.0 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 OAP62533.1 - 5.9e-07 30.0 2.7 0.017 15.5 0.0 4.4 4 1 0 4 4 4 2 AAA ATPase domain AAA_22 PF13401.6 OAP62533.1 - 7.7e-07 29.5 0.0 0.073 13.3 0.0 3.2 3 1 0 3 3 2 2 AAA domain T2SSE PF00437.20 OAP62533.1 - 9.6e-07 28.1 0.2 0.25 10.4 0.0 3.4 3 0 0 3 3 3 2 Type II/IV secretion system protein SMC_N PF02463.19 OAP62533.1 - 1.9e-05 24.2 0.4 6.1 6.2 0.0 4.2 4 0 0 4 4 4 0 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 OAP62533.1 - 2.9e-05 24.0 0.7 0.012 15.5 0.0 2.6 2 0 0 2 2 2 1 RsgA GTPase AAA_24 PF13479.6 OAP62533.1 - 8.7e-05 22.3 0.1 0.32 10.7 0.0 2.6 2 1 0 2 2 2 2 AAA domain AAA PF00004.29 OAP62533.1 - 0.00015 22.2 0.3 2.5 8.5 0.0 4.1 3 2 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 OAP62533.1 - 0.00058 19.8 0.0 0.025 14.5 0.0 2.4 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea FtsK_SpoIIIE PF01580.18 OAP62533.1 - 0.00096 18.6 0.1 1.5 8.1 0.0 2.8 3 0 0 3 3 3 2 FtsK/SpoIIIE family ATPase PF06745.13 OAP62533.1 - 0.0014 18.0 0.0 9.5 5.5 0.0 3.6 3 0 0 3 3 3 0 KaiC AAA_23 PF13476.6 OAP62533.1 - 0.0015 19.0 0.0 0.17 12.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 OAP62533.1 - 0.0024 17.9 1.5 1.2 9.3 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_7 PF12775.7 OAP62533.1 - 0.0035 16.9 0.1 2.5 7.6 0.0 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region DUF87 PF01935.17 OAP62533.1 - 0.0043 17.2 2.0 0.023 14.8 0.2 2.5 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_25 PF13481.6 OAP62533.1 - 0.0052 16.4 0.5 0.7 9.4 0.0 3.2 4 0 0 4 4 3 1 AAA domain RNA_helicase PF00910.22 OAP62533.1 - 0.0054 17.1 0.2 2.2 8.7 0.0 3.1 3 0 0 3 3 2 1 RNA helicase G-alpha PF00503.20 OAP62533.1 - 0.0082 15.3 0.1 0.71 9.0 0.0 2.6 3 0 0 3 3 3 1 G-protein alpha subunit AAA_33 PF13671.6 OAP62533.1 - 0.0091 16.2 0.1 8.6 6.5 0.0 3.2 2 1 0 2 2 2 0 AAA domain AAA_27 PF13514.6 OAP62533.1 - 0.0099 15.5 0.0 0.048 13.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain Roc PF08477.13 OAP62533.1 - 0.011 16.0 0.1 1.8 8.8 0.1 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NACHT PF05729.12 OAP62533.1 - 0.023 14.6 0.0 5.7 6.8 0.1 2.6 2 0 0 2 2 2 0 NACHT domain IstB_IS21 PF01695.17 OAP62533.1 - 0.026 14.3 0.1 1.7 8.3 0.0 3.4 4 0 0 4 4 4 0 IstB-like ATP binding protein AAA_14 PF13173.6 OAP62533.1 - 0.067 13.2 0.3 1.6 8.7 0.0 3.3 5 0 0 5 5 3 0 AAA domain ATP-synt_ab PF00006.25 OAP62533.1 - 0.072 12.7 0.0 2.7 7.6 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain GTP_EFTU PF00009.27 OAP62533.1 - 0.073 12.6 0.0 0.74 9.3 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_18 PF13238.6 OAP62533.1 - 0.079 13.5 0.7 16 6.0 0.0 3.4 4 1 0 4 4 2 0 AAA domain TniB PF05621.11 OAP62533.1 - 0.095 12.1 0.0 11 5.3 0.0 2.9 3 0 0 3 3 3 0 Bacterial TniB protein DUF815 PF05673.13 OAP62533.1 - 0.095 11.8 0.1 5.2 6.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_5 PF07728.14 OAP62533.1 - 0.12 12.4 0.8 10 6.1 0.0 3.9 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) PduV-EutP PF10662.9 OAP62533.1 - 0.13 12.1 1.1 4.5 7.0 0.1 2.8 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 OAP62533.1 - 0.14 11.6 0.8 1.6 8.2 0.0 2.9 4 0 0 4 4 3 0 Signal recognition particle receptor beta subunit Septin PF00735.18 OAP62533.1 - 0.16 11.2 0.0 5.8 6.1 0.0 2.2 2 0 0 2 2 2 0 Septin AIG1 PF04548.16 OAP62533.1 - 0.19 11.0 0.8 3.3 7.0 0.1 2.6 3 0 0 3 3 3 0 AIG1 family Dynamin_N PF00350.23 OAP62533.1 - 0.76 9.8 4.3 8.6 6.4 0.1 2.5 2 0 0 2 2 2 0 Dynamin family p450 PF00067.22 OAP62534.1 - 2.5e-58 197.9 0.0 3.5e-58 197.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DLH PF01738.18 OAP62535.1 - 9.3e-20 71.1 0.0 1.1e-19 70.9 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family DUF1275 PF06912.11 OAP62536.1 - 8.2e-48 162.9 13.8 1e-47 162.6 13.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) SLATT_3 PF18184.1 OAP62536.1 - 0.036 14.2 4.7 1.2 9.3 0.3 2.3 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 3 Acyl_transf_3 PF01757.22 OAP62536.1 - 0.1 11.7 15.9 0.0078 15.3 4.7 2.1 1 1 0 2 2 2 0 Acyltransferase family SLC3A2_N PF16028.5 OAP62536.1 - 0.13 11.8 0.5 0.39 10.3 0.2 2.0 2 0 0 2 2 2 0 Solute carrier family 3 member 2 N-terminus DUF1218 PF06749.12 OAP62536.1 - 0.45 11.1 6.5 0.18 12.4 1.2 2.8 3 1 0 3 3 3 0 Protein of unknown function (DUF1218) Cupin_1 PF00190.22 OAP62537.1 - 3.9e-42 143.4 0.0 3.8e-21 75.3 0.0 2.1 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 OAP62537.1 - 1.7e-24 85.3 1.2 2e-12 46.7 0.1 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 OAP62537.1 - 1.5e-09 37.4 0.0 0.00055 19.6 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.19 OAP62537.1 - 5.8e-08 32.7 0.3 0.00038 20.4 0.1 2.4 2 0 0 2 2 2 2 AraC-like ligand binding domain CENP-C_C PF11699.8 OAP62537.1 - 0.0057 16.9 0.0 3 8.1 0.0 2.9 3 0 0 3 3 3 1 Mif2/CENP-C like ARD PF03079.14 OAP62537.1 - 0.01 16.1 0.2 2.9 8.0 0.0 2.3 2 0 0 2 2 2 0 ARD/ARD' family Cupin_6 PF12852.7 OAP62537.1 - 0.049 13.3 0.0 6.6 6.4 0.0 2.2 2 0 0 2 2 2 0 Cupin Fungal_trans PF04082.18 OAP62538.1 - 6.7e-13 48.3 0.1 1.1e-12 47.6 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP62538.1 - 3.5e-08 33.4 9.7 6.3e-08 32.6 9.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAP62539.1 - 2e-13 50.0 0.1 3.5e-13 49.2 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pox_mRNA-cap PF03341.13 OAP62539.1 - 0.043 13.1 0.6 0.071 12.4 0.2 1.5 2 0 0 2 2 2 0 Poxvirus mRNA capping enzyme, small subunit Sugar_tr PF00083.24 OAP62540.1 - 1e-38 133.4 11.9 1.4e-38 133.0 11.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP62540.1 - 1.3e-10 40.8 11.6 1.8e-10 40.3 11.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_5 PF05631.14 OAP62540.1 - 7.5e-05 21.8 1.0 9.2e-05 21.5 1.0 1.1 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_2 PF13347.6 OAP62540.1 - 0.0083 14.7 6.0 0.011 14.3 6.0 1.2 1 0 0 1 1 1 1 MFS/sugar transport protein Sugar_tr PF00083.24 OAP62541.1 - 1.4e-41 142.9 3.3 1.6e-41 142.7 3.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MASE4 PF17158.4 OAP62541.1 - 0.0016 17.7 0.1 0.0024 17.2 0.1 1.2 1 0 0 1 1 1 1 Membrane-associated sensor, integral membrane domain DUF1772 PF08592.11 OAP62541.1 - 0.028 14.7 0.8 1.2 9.5 0.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) MFS_1_like PF12832.7 OAP62541.1 - 0.041 12.8 3.7 0.039 12.8 3.2 1.3 1 1 0 1 1 1 0 MFS_1 like family ADH_zinc_N PF00107.26 OAP62542.1 - 1.3e-25 89.8 0.5 2.4e-25 89.0 0.5 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAP62542.1 - 3.5e-05 24.8 0.0 5.5e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 OAP62542.1 - 0.0075 15.6 2.0 0.015 14.6 1.9 1.5 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ACP_syn_III PF08545.10 OAP62542.1 - 0.026 14.3 0.8 0.064 13.1 0.5 1.7 1 1 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III CRA_rpt PF07046.11 OAP62543.1 - 0.062 13.5 0.7 0.21 11.8 0.3 2.1 1 1 1 2 2 2 0 Cytoplasmic repetitive antigen (CRA) like repeat GCV_H PF01597.19 OAP62544.1 - 4.5e-42 142.8 1.5 5.6e-42 142.5 1.5 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.22 OAP62544.1 - 0.078 12.8 0.3 0.21 11.5 0.3 1.7 1 0 0 1 1 1 0 Biotin-requiring enzyme RnfC_N PF13375.6 OAP62544.1 - 0.093 12.7 0.1 0.17 11.9 0.1 1.4 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain Ribosomal_S6 PF01250.17 OAP62545.1 - 2.6e-23 82.1 0.0 3.3e-23 81.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S6 Dynamin_N PF00350.23 OAP62546.1 - 1.6e-43 148.7 0.0 3.1e-43 147.7 0.0 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 OAP62546.1 - 7.6e-15 54.9 0.0 2.2e-12 46.8 0.0 2.3 2 0 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.23 OAP62546.1 - 2.4e-05 24.4 0.0 0.0002 21.4 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_21 PF13304.6 OAP62546.1 - 0.043 13.6 0.0 0.086 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 OAP62546.1 - 0.051 14.0 0.0 0.22 11.9 0.0 2.1 1 0 0 1 1 1 0 AAA ATPase domain AAA_15 PF13175.6 OAP62546.1 - 0.058 13.1 0.0 0.22 11.2 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain Roc PF08477.13 OAP62546.1 - 0.059 13.6 0.0 0.68 10.2 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase GATase_4 PF13230.6 OAP62547.1 - 1.1e-14 54.0 0.0 1.1e-12 47.5 0.0 2.1 2 0 0 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.6 OAP62547.1 - 1.1e-08 35.3 0.0 2.2e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain PIG-Y PF15159.6 OAP62548.1 - 4.2e-23 82.0 8.6 6.2e-23 81.5 8.6 1.3 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y DUF1218 PF06749.12 OAP62548.1 - 0.14 12.7 1.1 11 6.6 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) Fas_alpha_ACP PF18325.1 OAP62549.1 - 2.4e-41 141.8 0.0 9.2e-33 113.9 0.0 2.4 2 0 0 2 2 2 2 Fatty acid synthase subunit alpha Acyl carrier domain FAS_I_H PF18314.1 OAP62549.1 - 5.2e-34 117.7 0.1 1.2e-33 116.4 0.1 1.6 1 0 0 1 1 1 1 Fatty acid synthase type I helical domain ketoacyl-synt PF00109.26 OAP62549.1 - 2.4e-23 83.0 1.4 6.1e-23 81.7 1.4 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 OAP62549.1 - 1.3e-15 57.5 0.0 5.5e-15 55.4 0.0 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.25 OAP62549.1 - 0.00011 21.7 0.0 0.00055 19.4 0.0 2.2 3 0 0 3 3 3 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP62549.1 - 0.00051 19.7 0.0 0.0013 18.3 0.0 1.7 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 2-Hacid_dh_C PF02826.19 OAP62549.1 - 0.068 12.5 0.1 0.17 11.2 0.1 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ACP_syn_III PF08545.10 OAP62549.1 - 0.26 11.1 0.8 4.1 7.3 0.1 2.9 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Cys_Met_Meta_PP PF01053.20 OAP62550.1 - 3.2e-116 388.0 0.0 3.8e-116 387.8 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 OAP62550.1 - 3.5e-10 39.4 0.3 6.7e-10 38.5 0.3 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 OAP62550.1 - 6e-08 32.2 0.0 9.2e-08 31.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 OAP62550.1 - 2.2e-07 30.5 0.1 3.8e-07 29.7 0.1 1.4 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family GDC-P PF02347.16 OAP62550.1 - 0.00063 18.7 0.0 0.001 18.0 0.0 1.2 1 0 0 1 1 1 1 Glycine cleavage system P-protein Met_gamma_lyase PF06838.11 OAP62550.1 - 0.035 12.6 0.0 0.053 12.0 0.0 1.2 1 0 0 1 1 1 0 Methionine gamma-lyase Beta_elim_lyase PF01212.21 OAP62550.1 - 0.046 13.0 0.0 0.094 12.0 0.0 1.5 1 0 0 1 1 1 0 Beta-eliminating lyase Abhydrolase_1 PF00561.20 OAP62551.1 - 8.8e-18 64.9 0.1 1.3e-17 64.3 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Ndr PF03096.14 OAP62551.1 - 0.00023 20.0 0.0 0.0004 19.2 0.0 1.3 1 0 0 1 1 1 1 Ndr family Hydrolase_4 PF12146.8 OAP62551.1 - 0.025 13.9 0.0 0.043 13.1 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OAP62551.1 - 0.064 13.8 0.5 0.35 11.5 0.5 1.9 1 1 1 2 2 2 0 Alpha/beta hydrolase family Cys_Met_Meta_PP PF01053.20 OAP62552.1 - 2.1e-117 391.9 0.0 2.4e-117 391.7 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 OAP62552.1 - 2.5e-11 43.3 0.0 9.9e-11 41.4 0.0 1.8 2 0 0 2 2 2 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 OAP62552.1 - 4.8e-08 32.7 0.1 8.2e-08 31.9 0.1 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 OAP62552.1 - 1.4e-07 30.9 0.4 3e-07 29.8 0.4 1.4 1 0 0 1 1 1 1 Aminotransferase class-V GDC-P PF02347.16 OAP62552.1 - 0.0031 16.4 0.0 0.0042 16.0 0.0 1.1 1 0 0 1 1 1 1 Glycine cleavage system P-protein Met_gamma_lyase PF06838.11 OAP62552.1 - 0.12 10.9 0.0 0.16 10.4 0.0 1.1 1 0 0 1 1 1 0 Methionine gamma-lyase ThiG PF05690.14 OAP62552.1 - 0.14 11.4 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG NAS PF03059.16 OAP62553.1 - 1.1e-26 93.8 0.0 1.4e-26 93.5 0.0 1.0 1 0 0 1 1 1 1 Nicotianamine synthase protein Methyltransf_25 PF13649.6 OAP62553.1 - 0.0024 18.5 0.0 0.0053 17.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain 2OG-FeII_Oxy PF03171.20 OAP62554.1 - 2e-13 50.7 0.0 3.9e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 OAP62554.1 - 1.5e-08 35.4 0.0 3.2e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Ad_Cy_reg PF16701.5 OAP62554.1 - 0.077 12.7 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Adenylate cyclase regulatory domain MFS_1 PF07690.16 OAP62555.1 - 1.2e-22 80.3 59.2 1.7e-21 76.5 24.5 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily BIV_Env PF05858.12 OAP62555.1 - 0.16 10.1 0.3 0.74 7.9 0.0 2.0 2 0 0 2 2 2 0 Bovine immunodeficiency virus surface protein (SU) Abhydrolase_1 PF00561.20 OAP62556.1 - 2e-39 135.8 0.0 2.9e-39 135.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAP62556.1 - 2.6e-05 25.0 0.4 5.4e-05 23.9 0.4 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 OAP62556.1 - 0.00015 21.5 0.4 0.00024 20.9 0.4 1.2 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 OAP62556.1 - 0.00025 20.4 0.0 0.00043 19.6 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 OAP62556.1 - 0.057 13.1 0.3 0.16 11.7 0.1 1.7 2 0 0 2 2 2 0 PGAP1-like protein ABC_tran PF00005.27 OAP62557.1 - 9.4e-38 129.8 0.0 9e-18 65.1 0.0 2.9 3 0 0 3 3 2 2 ABC transporter ABC_membrane PF00664.23 OAP62557.1 - 9.4e-27 94.3 30.6 1.3e-19 70.9 14.4 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 OAP62557.1 - 3.2e-07 30.0 0.9 0.41 10.0 0.0 4.3 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 OAP62557.1 - 3.9e-06 26.9 0.9 0.0077 16.1 0.0 3.5 3 1 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 OAP62557.1 - 5.4e-06 26.0 2.9 0.016 14.9 0.1 2.9 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_22 PF13401.6 OAP62557.1 - 3e-05 24.3 0.3 0.086 13.1 0.1 2.8 2 1 0 2 2 2 2 AAA domain AAA_18 PF13238.6 OAP62557.1 - 8.5e-05 23.1 0.0 0.038 14.5 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OAP62557.1 - 0.00022 21.7 0.0 0.013 15.8 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.23 OAP62557.1 - 0.00024 21.1 0.1 0.93 9.6 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OAP62557.1 - 0.00073 19.5 0.1 0.18 11.7 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_23 PF13476.6 OAP62557.1 - 0.0012 19.4 0.5 0.94 9.9 0.1 2.3 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 OAP62557.1 - 0.0013 18.3 0.0 1.4 8.4 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region DUF87 PF01935.17 OAP62557.1 - 0.0022 18.2 0.2 0.072 13.2 0.0 2.3 2 0 0 2 2 2 1 Helicase HerA, central domain FtsK_SpoIIIE PF01580.18 OAP62557.1 - 0.0022 17.4 0.0 0.35 10.2 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family Dynamin_N PF00350.23 OAP62557.1 - 0.0031 17.6 0.1 0.21 11.6 0.0 2.4 2 0 0 2 2 2 1 Dynamin family T2SSE PF00437.20 OAP62557.1 - 0.0036 16.4 0.0 0.12 11.4 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_33 PF13671.6 OAP62557.1 - 0.0037 17.4 0.3 0.1 12.8 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 OAP62557.1 - 0.01 15.4 0.0 0.83 9.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 OAP62557.1 - 0.011 15.5 0.1 0.052 13.3 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 OAP62557.1 - 0.013 15.3 0.1 0.19 11.5 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.22 OAP62557.1 - 0.023 15.1 0.1 6.5 7.2 0.0 2.8 2 0 0 2 2 2 0 RNA helicase AAA PF00004.29 OAP62557.1 - 0.06 13.8 1.0 0.9 10.0 0.1 2.9 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 OAP62557.1 - 0.28 10.9 2.1 19 4.9 0.0 3.4 4 0 0 4 4 4 0 IstB-like ATP binding protein ATP-grasp_4 PF13535.6 OAP62559.1 - 1.8e-13 50.4 0.0 6.5e-13 48.6 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_N PF18130.1 OAP62559.1 - 1.9e-13 50.8 0.0 1.7e-12 47.7 0.0 2.4 2 0 0 2 2 2 1 ATP-grasp N-terminal domain Dala_Dala_lig_C PF07478.13 OAP62559.1 - 1.6e-05 24.6 0.0 3.9e-05 23.3 0.0 1.6 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 OAP62559.1 - 0.005 16.9 0.0 0.08 13.0 0.0 2.4 3 0 0 3 3 3 1 ATP-grasp domain GARS_A PF01071.19 OAP62559.1 - 0.013 15.3 0.0 0.021 14.6 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATPgrasp_Ter PF15632.6 OAP62559.1 - 0.014 15.2 0.0 3.4 7.4 0.0 2.5 2 0 0 2 2 2 0 ATP-grasp in the biosynthetic pathway with Ter operon CPSase_L_D2 PF02786.17 OAP62559.1 - 0.018 14.5 0.0 0.047 13.2 0.0 1.8 1 1 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain HJURP_C PF12347.8 OAP62560.1 - 0.045 13.8 0.0 0.16 12.0 0.0 1.9 1 0 0 1 1 1 0 Holliday junction regulator protein family C-terminal repeat Strumpellin PF10266.9 OAP62560.1 - 0.082 10.6 0.0 0.13 9.9 0.0 1.2 1 0 0 1 1 1 0 Hereditary spastic paraplegia protein strumpellin ATPgrasp_N PF18130.1 OAP62561.1 - 1.3e-14 54.5 0.1 4.1e-14 52.9 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp N-terminal domain ATP-grasp_4 PF13535.6 OAP62561.1 - 5.7e-09 35.8 0.0 1.5e-08 34.4 0.0 1.7 1 1 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 OAP62561.1 - 7.2e-07 28.9 0.0 6.4e-06 25.8 0.0 2.0 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus CPSase_L_D2 PF02786.17 OAP62561.1 - 0.0011 18.5 0.0 0.019 14.5 0.0 2.1 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain GSH-S_ATP PF02955.16 OAP62561.1 - 0.015 14.7 0.0 0.028 13.8 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, ATP-grasp domain ATP-grasp_3 PF02655.14 OAP62561.1 - 0.063 13.3 0.0 0.16 12.0 0.0 1.7 1 0 0 1 1 1 0 ATP-grasp domain 4HBT_2 PF13279.6 OAP62562.1 - 6.8e-06 26.6 0.0 9.4e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Ank_2 PF12796.7 OAP62563.1 - 1.1e-08 35.5 0.0 1.7e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 OAP62563.1 - 2.3e-08 34.1 0.2 0.00087 19.6 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 OAP62563.1 - 5.2e-08 32.6 0.0 0.00049 20.3 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 OAP62563.1 - 3e-07 30.6 0.0 0.00013 22.2 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 OAP62563.1 - 5e-06 26.9 0.0 9.3e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (many copies) bZIP_1 PF00170.21 OAP62563.1 - 0.7 10.0 13.7 1.1 9.4 13.7 1.2 1 0 0 1 1 1 0 bZIP transcription factor DUF1729 PF08354.10 OAP62564.1 - 6e-144 479.3 0.0 1.1e-143 478.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) Acyl_transf_1 PF00698.21 OAP62564.1 - 3.7e-52 177.8 0.0 8.1e-52 176.7 0.0 1.6 1 0 0 1 1 1 1 Acyl transferase domain SAT PF16073.5 OAP62564.1 - 2e-31 109.6 0.0 3.3e-31 108.9 0.0 1.4 1 0 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis FAS_meander PF17951.1 OAP62564.1 - 8e-23 80.9 0.0 1.7e-22 79.8 0.0 1.5 1 0 0 1 1 1 1 Fatty acid synthase meander beta sheet domain MaoC_dehydratas PF01575.19 OAP62564.1 - 1.1e-22 79.9 0.0 3e-22 78.5 0.0 1.7 1 0 0 1 1 1 1 MaoC like domain FAS_N PF17828.1 OAP62564.1 - 7.6e-08 32.4 0.0 1.9e-07 31.1 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta MaoC_dehydrat_N PF13452.6 OAP62564.1 - 4e-05 23.8 0.2 0.0011 19.1 0.0 2.9 2 1 0 2 2 2 1 N-terminal half of MaoC dehydratase Aminotran_4 PF01063.19 OAP62565.1 - 3.3e-22 79.5 0.0 4.8e-22 78.9 0.0 1.2 1 0 0 1 1 1 1 Amino-transferase class IV p450 PF00067.22 OAP62566.1 - 1e-70 238.8 0.0 1.3e-70 238.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DAO PF01266.24 OAP62567.1 - 6.2e-43 147.7 0.0 7.2e-43 147.5 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 OAP62567.1 - 1.9e-05 24.7 0.6 0.0031 17.5 0.1 2.8 3 0 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 OAP62567.1 - 0.00013 22.1 0.1 0.00059 20.0 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 OAP62567.1 - 0.00055 19.3 0.0 0.19 11.0 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 OAP62567.1 - 0.001 18.4 0.0 0.22 10.8 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAP62567.1 - 0.0031 16.3 0.0 0.37 9.4 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_2 PF07992.14 OAP62567.1 - 0.02 14.2 0.0 0.083 12.1 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAP62567.1 - 0.043 13.0 0.1 0.11 11.7 0.0 1.6 2 0 0 2 2 2 0 Thi4 family Abhydrolase_6 PF12697.7 OAP62568.1 - 1.1e-08 36.0 0.0 1.4e-08 35.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAP62568.1 - 2.9e-05 23.9 0.0 8.3e-05 22.3 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold MOSC PF03473.17 OAP62569.1 - 3.7e-23 82.0 0.0 2.4e-22 79.3 0.0 2.3 2 0 0 2 2 2 1 MOSC domain Fer2 PF00111.27 OAP62569.1 - 4.1e-12 45.9 2.0 8.8e-12 44.8 2.0 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain 3-alpha PF03475.14 OAP62569.1 - 2e-11 43.6 0.1 3.5e-11 42.8 0.1 1.4 1 0 0 1 1 1 1 3-alpha domain Glyco_hydro_3_C PF01915.22 OAP62570.1 - 4.5e-45 154.1 0.0 1e-44 153.0 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 OAP62570.1 - 4.3e-35 121.6 0.0 7.7e-35 120.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 OAP62570.1 - 5e-23 81.0 0.0 1e-22 80.0 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF2921 PF11145.8 OAP62571.1 - 0.072 10.9 0.2 0.1 10.4 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2921) Cation_efflux PF01545.21 OAP62572.1 - 6.4e-15 55.4 9.4 8.2e-15 55.1 9.4 1.1 1 0 0 1 1 1 1 Cation efflux family IF3_C PF00707.22 OAP62573.1 - 5.2e-10 39.1 0.9 1.2e-09 38.0 0.9 1.6 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain mIF3 PF14877.6 OAP62573.1 - 9.2e-07 28.7 8.5 2.1e-06 27.6 8.4 1.7 1 1 0 1 1 1 1 Mitochondrial translation initiation factor Pep_M12B_propep PF01562.19 OAP62573.1 - 0.14 12.4 0.8 0.24 11.6 0.8 1.3 1 0 0 1 1 1 0 Reprolysin family propeptide GDA1_CD39 PF01150.17 OAP62574.1 - 1.1e-99 334.1 0.0 1.3e-99 333.7 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family PUL PF08324.11 OAP62575.1 - 4.7e-46 157.3 0.4 8e-46 156.5 0.4 1.3 1 0 0 1 1 1 1 PUL domain Peptidase_C97 PF05903.14 OAP62575.1 - 4e-38 130.6 0.0 9.3e-38 129.4 0.0 1.6 1 0 0 1 1 1 1 PPPDE putative peptidase domain Thioredoxin PF00085.20 OAP62575.1 - 2.2e-11 43.7 0.0 4.8e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 OAP62575.1 - 0.00011 22.7 0.1 0.00038 20.9 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain TraF PF13728.6 OAP62575.1 - 0.00076 19.4 0.0 0.002 18.0 0.0 1.7 2 0 0 2 2 2 1 F plasmid transfer operon protein AhpC-TSA PF00578.21 OAP62575.1 - 0.12 12.3 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 AhpC/TSA family EF-hand_9 PF14658.6 OAP62576.1 - 6.7e-07 29.5 0.0 0.0012 19.1 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain ORC6 PF05460.13 OAP62576.1 - 0.00011 21.6 0.6 0.00012 21.5 0.6 1.0 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) EF-hand_7 PF13499.6 OAP62576.1 - 0.0011 19.4 0.2 0.024 15.1 0.0 2.7 2 1 1 3 3 3 1 EF-hand domain pair Sin3a_C PF16879.5 OAP62576.1 - 0.12 12.1 0.2 0.22 11.2 0.1 1.4 1 1 0 1 1 1 0 C-terminal domain of Sin3a protein Skp1 PF01466.19 OAP62576.1 - 0.35 11.0 3.1 0.33 11.1 0.4 2.2 2 0 0 2 2 2 0 Skp1 family, dimerisation domain PalH PF08733.10 OAP62578.1 - 8.3e-114 380.0 0.0 1e-113 379.7 0.0 1.1 1 0 0 1 1 1 1 PalH/RIM21 Abhydrolase_2 PF02230.16 OAP62579.1 - 2e-22 80.1 0.0 1e-14 54.9 0.2 2.8 1 1 1 2 2 2 2 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 OAP62579.1 - 3.6e-06 26.6 0.0 5.4e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 OAP62579.1 - 0.027 13.8 0.0 1.3 8.3 0.0 2.7 2 1 1 3 3 3 0 Serine aminopeptidase, S33 Zn_clus PF00172.18 OAP62580.1 - 7.2e-07 29.2 11.6 1.3e-06 28.5 11.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Atg14 PF10186.9 OAP62581.1 - 1.8e-12 47.0 14.1 2.4e-11 43.3 14.1 2.1 1 1 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 VPS38 PF17649.1 OAP62581.1 - 9.1e-09 34.7 1.3 0.0016 17.4 0.0 3.2 3 0 0 3 3 3 3 Vacuolar protein sorting 38 APG6 PF04111.12 OAP62581.1 - 0.00088 19.3 0.0 0.0016 18.4 0.0 1.4 1 0 0 1 1 1 1 Apg6 BARA domain DUF3557 PF12078.8 OAP62581.1 - 0.042 13.8 0.0 0.089 12.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3557) Golgin_A5 PF09787.9 OAP62581.1 - 0.71 9.3 9.4 1.1 8.7 9.4 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 CAP PF00188.26 OAP62583.1 - 4.7e-09 37.1 2.5 8.6e-09 36.3 2.5 1.4 1 1 0 1 1 1 1 Cysteine-rich secretory protein family Snf7 PF03357.21 OAP62584.1 - 1.9e-36 125.3 19.0 3.3e-36 124.5 18.2 1.6 2 0 0 2 2 2 1 Snf7 YlqD PF11068.8 OAP62584.1 - 0.043 14.2 17.7 1.2 9.5 6.5 2.1 1 1 1 2 2 2 0 YlqD protein Remorin_C PF03763.13 OAP62584.1 - 0.68 9.8 8.4 1.5 8.8 8.1 1.8 1 1 0 1 1 1 0 Remorin, C-terminal region DUF3958 PF13125.6 OAP62584.1 - 4.9 7.4 13.3 0.16 12.2 4.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3958) Dynamin_N PF00350.23 OAP62585.1 - 1.4e-18 67.5 0.0 1.4e-18 67.5 0.0 2.2 3 0 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.23 OAP62585.1 - 3.8e-10 39.9 0.0 5e-09 36.3 0.0 2.9 2 2 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OAP62585.1 - 4e-07 29.8 1.6 1.3e-05 24.8 1.6 2.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IIGP PF05049.13 OAP62585.1 - 0.014 14.5 0.0 0.057 12.5 0.0 1.9 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) CobU PF02283.16 OAP62585.1 - 0.021 14.4 0.2 1.3 8.6 0.1 2.7 3 0 0 3 3 3 0 Cobinamide kinase / cobinamide phosphate guanyltransferase AAA_18 PF13238.6 OAP62585.1 - 0.043 14.4 0.5 0.18 12.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 OAP62585.1 - 0.073 13.1 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE FeoB_N PF02421.18 OAP62585.1 - 0.2 11.1 2.0 36 3.8 0.0 3.6 4 0 0 4 4 4 0 Ferrous iron transport protein B Roc PF08477.13 OAP62585.1 - 0.21 11.8 0.7 3.6 7.8 0.0 3.1 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase PP2C PF00481.21 OAP62586.1 - 9.7e-63 212.2 0.4 8.1e-52 176.4 0.4 3.3 1 1 0 2 2 2 2 Protein phosphatase 2C Mit_KHE1 PF10173.9 OAP62586.1 - 0.061 13.4 0.1 0.19 11.8 0.1 1.9 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related Pyr_redox_2 PF07992.14 OAP62587.1 - 7.6e-53 179.6 0.0 9.9e-53 179.3 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAP62587.1 - 1.8e-11 44.4 0.0 9.1e-10 39.0 0.0 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAP62587.1 - 0.00043 19.6 0.9 0.27 10.5 0.1 2.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Ribosomal_L27A PF00828.19 OAP62588.1 - 8.5e-31 107.3 0.3 1.3e-30 106.7 0.3 1.3 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A MFS_1 PF07690.16 OAP62589.1 - 2.9e-34 118.6 29.5 3.9e-34 118.1 29.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1648 PF07853.11 OAP62589.1 - 0.087 12.5 3.7 4.6 7.0 0.6 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1648) DUF4381 PF14316.6 OAP62589.1 - 0.24 11.7 2.3 7.8 6.7 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4381) EcKinase PF02958.20 OAP62590.1 - 6.5e-23 81.5 0.0 6.2e-22 78.3 0.0 2.1 1 1 0 1 1 1 1 Ecdysteroid kinase APH PF01636.23 OAP62590.1 - 2.7e-18 66.8 0.1 7.7e-18 65.3 0.1 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family DUF1679 PF07914.11 OAP62590.1 - 1.1e-06 27.8 0.0 1.9e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) Choline_kinase PF01633.20 OAP62590.1 - 0.23 11.0 0.0 0.54 9.8 0.0 1.5 2 0 0 2 2 2 0 Choline/ethanolamine kinase p450 PF00067.22 OAP62591.1 - 2.6e-61 207.8 0.0 3.7e-61 207.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 TetR_C_28 PF17937.1 OAP62591.1 - 0.033 14.6 0.0 0.085 13.3 0.0 1.7 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Glyco_transf_90 PF05686.12 OAP62592.1 - 1.2e-14 54.1 7.8 6.5e-06 25.3 0.1 4.2 4 1 0 4 4 4 3 Glycosyl transferase family 90 DUF3328 PF11807.8 OAP62592.1 - 1.4 8.7 5.4 23 4.7 3.8 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF3328) Trypan_PARP PF05887.11 OAP62592.1 - 2.3 8.2 16.2 4.4 7.3 16.2 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Spb1_C PF07780.12 OAP62593.1 - 1.7e-80 269.6 13.2 1.7e-80 269.6 13.2 3.0 3 0 0 3 3 3 1 Spb1 C-terminal domain FtsJ PF01728.19 OAP62593.1 - 2.1e-57 194.1 0.1 3.7e-57 193.3 0.1 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.8 OAP62593.1 - 1.4e-53 181.1 14.9 1.4e-53 181.1 14.9 3.8 5 0 0 5 5 5 1 Domain of unknown function (DUF3381) Methyltr_RsmB-F PF01189.17 OAP62593.1 - 0.053 13.1 0.0 0.15 11.6 0.0 1.8 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Methyltransf_23 PF13489.6 OAP62593.1 - 0.1 12.4 0.0 0.29 11.0 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Ribosomal_L4 PF00573.22 OAP62594.1 - 1.1e-44 152.5 0.0 1.7e-44 151.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Fungal_trans PF04082.18 OAP62595.1 - 3.5e-37 127.9 0.1 5e-37 127.4 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP62595.1 - 4.7e-08 33.0 8.7 8.4e-08 32.2 8.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Snf7 PF03357.21 OAP62596.1 - 1.4e-19 70.3 19.6 5.7e-19 68.4 18.5 2.4 2 1 0 2 2 2 1 Snf7 zf-C3HC4_2 PF13923.6 OAP62597.1 - 3.4e-10 39.6 13.5 3.4e-10 39.6 13.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAP62597.1 - 1.3e-07 31.3 13.5 1.3e-07 31.3 13.5 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAP62597.1 - 4e-07 30.0 11.1 4e-07 30.0 11.1 2.0 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 OAP62597.1 - 1e-06 28.5 10.9 1e-06 28.5 10.9 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAP62597.1 - 6.1e-06 26.1 13.4 6.1e-06 26.1 13.4 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 OAP62597.1 - 1.6e-05 25.0 13.1 1.6e-05 25.0 13.1 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 OAP62597.1 - 2.6e-05 24.0 4.6 2.6e-05 24.0 4.6 1.7 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-RING_2 PF13639.6 OAP62597.1 - 8.5e-05 22.8 13.3 8.5e-05 22.8 13.3 2.3 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 OAP62597.1 - 0.00029 21.1 6.4 0.00029 21.1 6.4 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_10 PF16685.5 OAP62597.1 - 0.0068 16.5 7.5 0.015 15.4 7.5 1.6 1 0 0 1 1 1 1 zinc RING finger of MSL2 Prok-RING_4 PF14447.6 OAP62597.1 - 0.0071 16.2 17.3 0.017 15.0 10.4 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 OAP62597.1 - 0.0073 16.1 7.1 0.0073 16.1 7.1 2.5 2 1 1 3 3 3 1 RING/Ubox like zinc-binding domain U-box PF04564.15 OAP62597.1 - 0.024 14.8 0.0 0.19 12.0 0.0 2.3 2 0 0 2 2 2 0 U-box domain zf-WRNIP1_ubi PF18279.1 OAP62597.1 - 0.07 13.8 1.5 0.07 13.8 1.5 2.7 3 0 0 3 3 3 0 Werner helicase-interacting protein 1 ubiquitin-binding domain SAP PF02037.27 OAP62597.1 - 0.073 12.9 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 SAP domain DHHW PF14286.6 OAP62597.1 - 0.18 11.1 0.5 0.28 10.4 0.5 1.2 1 0 0 1 1 1 0 DHHW protein zf-ANAPC11 PF12861.7 OAP62597.1 - 8 6.6 8.5 0.5 10.5 3.3 1.7 2 0 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger TRAPPC-Trs85 PF12739.7 OAP62598.1 - 4.7e-110 368.3 1.4 1.3e-109 366.9 1.1 1.7 2 0 0 2 2 2 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit TPR_2 PF07719.17 OAP62598.1 - 1.1 9.5 5.7 2.8 8.3 0.3 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 OAP62598.1 - 3 8.6 5.7 39 5.0 0.3 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Mito_carr PF00153.27 OAP62599.1 - 4.3e-67 222.1 2.2 4.6e-21 74.6 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 OAP62599.1 - 3.8e-22 78.5 3.7 1.5e-11 44.6 0.6 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 OAP62599.1 - 1.7e-20 71.0 1.5 7.9e-07 28.2 0.6 4.5 4 0 0 4 4 4 3 EF hand EF-hand_5 PF13202.6 OAP62599.1 - 2.7e-18 64.6 4.3 7.7e-07 28.3 0.7 3.6 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 OAP62599.1 - 9e-18 62.6 4.9 0.00019 21.1 0.0 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 OAP62599.1 - 2e-12 46.7 0.4 5.6e-05 22.9 0.1 3.5 3 1 1 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 OAP62599.1 - 9.6e-09 35.6 0.2 0.00013 22.2 0.1 2.3 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 OAP62599.1 - 0.0056 16.6 2.4 0.079 12.9 0.3 2.9 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 OAP62599.1 - 0.0084 16.3 1.7 0.95 9.7 0.1 2.7 3 0 0 3 3 3 1 Dockerin type I domain Serine_protease PF18405.1 OAP62599.1 - 0.032 13.4 0.3 8.2 5.5 0.1 3.0 3 0 0 3 3 3 0 Gammaproteobacterial serine protease EF-hand_10 PF14788.6 OAP62599.1 - 0.041 13.7 0.8 16 5.4 0.0 3.7 5 0 0 5 5 5 0 EF hand EF-hand_11 PF08976.11 OAP62599.1 - 0.051 14.5 0.3 0.2 12.6 0.0 2.1 2 1 0 2 2 2 0 EF-hand domain DUF5580 PF17743.1 OAP62599.1 - 0.057 12.0 0.0 0.089 11.3 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5580) Cyclin_N PF00134.23 OAP62600.1 - 2e-12 47.0 1.0 6.8e-11 42.0 0.4 2.3 1 1 1 2 2 2 1 Cyclin, N-terminal domain RNB PF00773.19 OAP62600.1 - 0.027 13.8 0.4 0.04 13.2 0.4 1.2 1 0 0 1 1 1 0 RNB domain Cyclin_C_2 PF16899.5 OAP62600.1 - 0.071 13.5 0.5 0.72 10.3 0.0 2.5 2 0 0 2 2 2 0 Cyclin C-terminal domain RPA_interact_M PF14767.6 OAP62600.1 - 0.17 12.5 1.3 1.1 9.8 0.0 2.5 3 0 0 3 3 3 0 Replication protein A interacting middle TFCD_C PF12612.8 OAP62601.1 - 1.5e-19 70.6 0.9 1.5e-19 70.6 0.9 3.0 3 0 0 3 3 3 1 Tubulin folding cofactor D C terminal HEAT PF02985.22 OAP62601.1 - 0.00026 21.0 8.2 0.014 15.6 0.0 5.7 5 0 0 5 5 5 1 HEAT repeat IFRD PF05004.13 OAP62601.1 - 0.00043 19.5 1.0 0.0088 15.2 0.2 2.7 2 1 0 2 2 2 1 Interferon-related developmental regulator (IFRD) HEAT_EZ PF13513.6 OAP62601.1 - 0.0015 19.0 3.6 0.028 14.9 0.1 4.9 5 0 0 5 5 5 1 HEAT-like repeat HEAT_2 PF13646.6 OAP62601.1 - 0.022 15.2 7.6 0.043 14.2 0.1 3.9 4 0 0 4 4 4 0 HEAT repeats Vac14_Fab1_bd PF12755.7 OAP62601.1 - 0.023 15.3 0.1 5.2 7.7 0.0 3.5 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region BTAD PF03704.17 OAP62601.1 - 0.12 12.8 0.7 0.47 10.9 0.7 2.0 1 0 0 1 1 1 0 Bacterial transcriptional activator domain 2OG-FeII_Oxy_5 PF13759.6 OAP62602.1 - 0.025 15.0 0.0 0.057 13.8 0.0 1.6 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase DNA_pol_B PF00136.21 OAP62603.1 - 6.9e-146 486.5 5.2 9.4e-146 486.1 5.2 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 OAP62603.1 - 6e-82 275.5 0.1 1e-81 274.7 0.1 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 OAP62603.1 - 7e-19 68.1 5.7 1.6e-18 66.9 5.7 1.7 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_exo2 PF10108.9 OAP62603.1 - 0.004 16.9 0.1 0.0087 15.8 0.1 1.5 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 OAP62603.1 - 0.01 15.9 0.2 0.057 13.4 0.2 2.2 1 1 0 1 1 1 0 RNase_H superfamily DASH_Spc19 PF08287.11 OAP62603.1 - 0.017 15.0 0.0 1.3 8.9 0.0 3.1 3 0 0 3 3 3 0 Spc19 C1_1 PF00130.22 OAP62603.1 - 0.078 12.9 7.8 0.34 10.8 1.3 2.5 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Rho_GDI PF02115.17 OAP62604.1 - 3.6e-64 216.1 0.1 3.9e-64 216.0 0.1 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor Metallophos PF00149.28 OAP62605.1 - 1.7e-36 126.6 0.4 2.3e-36 126.2 0.4 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 OAP62605.1 - 0.01 16.3 0.2 0.023 15.1 0.2 1.7 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain adh_short PF00106.25 OAP62607.1 - 3.8e-50 170.1 0.5 5.3e-50 169.6 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP62607.1 - 3.7e-34 118.3 0.3 4.6e-34 118.0 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP62607.1 - 3.8e-15 56.2 0.2 1.3e-14 54.5 0.2 1.8 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OAP62607.1 - 0.0073 15.5 0.3 0.018 14.2 0.1 1.7 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 OAP62607.1 - 0.013 15.8 0.1 0.027 14.7 0.1 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain THF_DHG_CYH_C PF02882.19 OAP62607.1 - 0.025 13.9 0.4 0.5 9.7 0.1 2.8 3 0 0 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain RasGEF PF00617.19 OAP62608.1 - 1.2e-57 195.0 0.9 2.5e-57 193.9 0.9 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 OAP62608.1 - 3.8e-29 101.0 0.1 9.3e-29 99.8 0.1 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.28 OAP62608.1 - 1.3e-14 53.5 0.6 5e-14 51.6 0.1 2.3 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 OAP62608.1 - 3.5e-13 49.2 0.1 7.7e-13 48.1 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 OAP62608.1 - 7.7e-10 38.3 0.0 1.5e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.26 OAP62608.1 - 0.00032 20.7 0.0 0.0011 19.0 0.0 2.0 2 0 0 2 2 2 1 WW domain FAD_binding_3 PF01494.19 OAP62609.1 - 2e-19 70.0 5.3 7.9e-15 55.0 0.0 2.8 2 1 0 3 3 3 2 FAD binding domain DAO PF01266.24 OAP62609.1 - 1e-11 45.1 9.9 7e-08 32.4 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAP62609.1 - 5.1e-09 35.8 6.6 0.00057 19.2 0.1 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAP62609.1 - 2.3e-07 31.3 3.4 0.006 17.1 1.3 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAP62609.1 - 7.6e-07 29.3 2.9 2.1e-06 27.8 2.9 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 OAP62609.1 - 0.00038 19.9 1.2 0.00059 19.3 1.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 OAP62609.1 - 0.0006 19.2 3.5 0.17 11.1 1.5 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Thi4 PF01946.17 OAP62609.1 - 0.00068 19.0 1.2 0.0011 18.2 1.2 1.3 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 OAP62609.1 - 0.0011 18.1 0.4 0.0017 17.6 0.4 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A Trp_halogenase PF04820.14 OAP62609.1 - 0.0014 17.6 4.6 0.41 9.4 0.0 2.6 2 0 0 2 2 2 2 Tryptophan halogenase FAD_binding_2 PF00890.24 OAP62609.1 - 0.0018 17.5 9.0 0.0058 15.8 6.8 2.1 2 0 0 2 2 2 1 FAD binding domain SE PF08491.10 OAP62609.1 - 0.0064 15.6 0.0 0.013 14.6 0.0 1.4 1 1 0 1 1 1 1 Squalene epoxidase Pyr_redox_3 PF13738.6 OAP62609.1 - 0.015 14.5 7.1 0.24 10.6 5.2 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAP62609.1 - 0.021 13.5 7.0 0.14 10.9 4.5 2.1 2 0 0 2 2 2 0 HI0933-like protein PaRep2a PF07903.11 OAP62609.1 - 0.12 12.2 0.1 0.25 11.2 0.1 1.5 1 0 0 1 1 1 0 PaRep2a protein Lycopene_cycl PF05834.12 OAP62609.1 - 0.19 10.7 1.9 0.68 8.9 1.9 1.8 1 1 0 1 1 1 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 OAP62609.1 - 0.63 10.0 5.8 3.4 7.6 0.1 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding Fungal_trans PF04082.18 OAP62610.1 - 1.1e-15 57.5 1.8 1.7e-15 56.8 1.8 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.6 OAP62610.1 - 9.2e-07 29.0 16.4 2.8e-05 24.3 5.9 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 OAP62610.1 - 4.3e-05 23.7 14.6 0.005 17.2 5.2 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAP62610.1 - 0.00033 21.2 12.6 0.12 13.2 3.9 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 OAP62610.1 - 0.096 13.4 0.3 2.3 8.9 0.3 2.5 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats PyrI_C PF02748.15 OAP62610.1 - 0.52 10.3 2.8 0.27 11.2 0.2 1.8 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Zn-ribbon_8 PF09723.10 OAP62610.1 - 2.3 8.4 4.6 6.7 6.9 4.6 1.8 1 0 0 1 1 1 0 Zinc ribbon domain zf-C2H2_jaz PF12171.8 OAP62610.1 - 2.3 8.6 7.3 0.63 10.4 3.8 2.0 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding DivIC PF04977.15 OAP62611.1 - 0.00086 19.0 2.9 0.00086 19.0 2.9 3.4 3 0 0 3 3 3 1 Septum formation initiator bZIP_2 PF07716.15 OAP62611.1 - 0.0013 18.8 25.4 0.31 11.2 2.5 4.6 4 1 1 5 5 4 3 Basic region leucine zipper bZIP_1 PF00170.21 OAP62611.1 - 0.0068 16.5 15.6 0.85 9.8 4.8 3.5 3 0 0 3 3 3 2 bZIP transcription factor ADIP PF11559.8 OAP62611.1 - 0.013 15.6 1.7 0.013 15.6 1.7 3.0 4 0 0 4 4 2 0 Afadin- and alpha -actinin-Binding HALZ PF02183.18 OAP62611.1 - 0.021 15.1 7.8 0.36 11.1 2.1 3.0 2 0 0 2 2 2 0 Homeobox associated leucine zipper zf-CpG_bind_C PF12269.8 OAP62611.1 - 0.046 13.5 0.5 0.046 13.5 0.5 3.0 4 0 0 4 4 4 0 CpG binding protein zinc finger C terminal domain DUF2076 PF09849.9 OAP62611.1 - 0.053 13.5 0.2 0.27 11.3 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) Sipho_Gp157 PF05565.11 OAP62611.1 - 0.18 11.8 4.2 0.32 11.0 0.3 2.4 2 0 0 2 2 2 0 Siphovirus Gp157 ABC_tran_CTD PF16326.5 OAP62611.1 - 0.2 11.9 8.2 3.2 8.1 2.1 3.5 3 0 0 3 3 3 0 ABC transporter C-terminal domain GIT_CC PF16559.5 OAP62611.1 - 0.21 11.5 9.0 12 5.8 0.5 3.7 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor Seryl_tRNA_N PF02403.22 OAP62611.1 - 0.39 11.0 8.2 0.13 12.5 1.0 3.0 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Pox_A_type_inc PF04508.12 OAP62611.1 - 0.41 10.6 0.1 0.41 10.6 0.1 3.4 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat DUF465 PF04325.13 OAP62611.1 - 0.69 10.0 6.3 7.6 6.7 2.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF465) Spc7 PF08317.11 OAP62611.1 - 0.96 8.3 10.9 2.1 7.1 2.3 2.5 2 0 0 2 2 2 0 Spc7 kinetochore protein Ax_dynein_light PF10211.9 OAP62611.1 - 1.1 9.2 11.4 0.46 10.4 1.7 3.2 3 0 0 3 3 3 0 Axonemal dynein light chain DUF4140 PF13600.6 OAP62611.1 - 1.3 9.5 7.8 7.2 7.1 2.4 3.0 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) JIP_LZII PF16471.5 OAP62611.1 - 1.7 8.8 12.5 0.51 10.5 2.6 3.6 3 0 0 3 3 3 0 JNK-interacting protein leucine zipper II MTBP_C PF14920.6 OAP62611.1 - 2.2 8.0 12.3 0.9 9.2 1.4 2.5 1 1 2 3 3 3 0 MDM2-binding ZapB PF06005.12 OAP62611.1 - 2.5 8.6 20.1 0.3 11.5 4.0 3.2 3 0 0 3 3 3 0 Cell division protein ZapB FlaC_arch PF05377.11 OAP62611.1 - 2.5 8.5 7.7 3.6 8.0 0.6 3.2 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) MCC-bdg_PDZ PF10506.9 OAP62611.1 - 3.8 7.6 9.3 10 6.2 1.2 2.7 2 0 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome TSC22 PF01166.18 OAP62611.1 - 3.8 7.9 12.5 9.2 6.7 0.5 3.2 3 0 0 3 3 3 0 TSC-22/dip/bun family UQ_con PF00179.26 OAP62612.1 - 7.4e-17 61.3 0.0 1.3e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme SOG2 PF10428.9 OAP62612.1 - 0.052 12.8 13.2 0.074 12.3 13.2 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein FAM220 PF15487.6 OAP62612.1 - 0.25 11.0 6.0 0.23 11.0 5.1 1.3 1 1 0 1 1 1 0 FAM220 family PAT1 PF09770.9 OAP62612.1 - 0.33 9.2 7.2 0.41 8.9 7.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4551 PF15087.6 OAP62612.1 - 0.84 8.4 5.8 1.1 8.0 5.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Parathyroid PF01279.17 OAP62612.1 - 1.9 9.2 4.8 2.6 8.7 0.4 2.5 2 1 0 2 2 2 0 Parathyroid hormone family SPX PF03105.19 OAP62612.1 - 4.7 7.0 9.9 6.8 6.5 9.9 1.2 1 0 0 1 1 1 0 SPX domain DHHC PF01529.20 OAP62613.1 - 1.1e-19 70.8 5.5 1.6e-19 70.3 5.5 1.2 1 0 0 1 1 1 1 DHHC palmitoyltransferase Yip1 PF04893.17 OAP62613.1 - 0.0018 18.1 2.0 0.0028 17.4 2.0 1.2 1 0 0 1 1 1 1 Yip1 domain CitMHS PF03600.16 OAP62613.1 - 0.4 9.8 1.7 0.58 9.3 1.7 1.1 1 0 0 1 1 1 0 Citrate transporter Acetyltransf_7 PF13508.7 OAP62614.1 - 1.2e-06 28.8 0.0 1.9e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAP62614.1 - 1.8e-06 28.1 0.0 2.9e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 OAP62614.1 - 4.2e-05 23.6 0.1 0.00023 21.2 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OAP62614.1 - 0.00032 20.6 0.0 0.00054 19.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 OAP62614.1 - 0.0025 17.9 0.0 0.0055 16.8 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 OAP62614.1 - 0.0046 16.9 0.0 0.0088 16.0 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Sugar_tr PF00083.24 OAP62615.1 - 1.9e-116 389.6 20.3 2.2e-116 389.4 20.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP62615.1 - 5.8e-20 71.5 44.6 1.7e-16 60.1 12.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2264 PF10022.9 OAP62616.1 - 3e-128 427.8 3.6 1.2e-125 419.3 3.6 2.1 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) RPA_C PF08784.11 OAP62617.1 - 3.6e-17 62.9 0.1 6.6e-17 62.1 0.1 1.5 1 0 0 1 1 1 1 Replication protein A C terminal tRNA_anti-codon PF01336.25 OAP62617.1 - 6.3e-07 29.3 0.1 1.4e-06 28.2 0.0 1.6 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain Polysacc_syn_2C PF08485.10 OAP62617.1 - 0.13 12.0 0.0 0.52 10.0 0.0 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein C-terminal HTH_36 PF13730.6 OAP62617.1 - 0.14 12.1 0.0 0.34 10.9 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain DEAD PF00270.29 OAP62618.1 - 1.9e-49 167.8 0.2 6.7e-49 166.0 0.0 2.0 2 1 1 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAP62618.1 - 7.7e-25 87.4 0.0 4.9e-24 84.8 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 OAP62618.1 - 2.1e-20 72.7 3.3 5.6e-20 71.4 3.3 1.8 1 0 0 1 1 1 1 DBP10CT (NUC160) domain ERCC3_RAD25_C PF16203.5 OAP62618.1 - 0.0038 16.5 0.0 0.0072 15.6 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase PBP_N PF17093.5 OAP62619.1 - 0.036 14.3 1.6 0.1 12.9 1.6 1.8 1 0 0 1 1 1 0 Penicillin-binding protein N-terminus VIT1 PF01988.19 OAP62619.1 - 0.34 10.7 3.2 0.35 10.7 3.1 1.3 1 1 0 1 1 1 0 VIT family CPBP PF02517.16 OAP62619.1 - 8 6.9 7.7 0.52 10.7 2.6 1.7 2 0 0 2 2 2 0 CPBP intramembrane metalloprotease LDB19 PF13002.7 OAP62620.1 - 1.1e-47 162.3 0.5 2.3e-47 161.2 0.3 1.6 2 0 0 2 2 2 1 Arrestin_N terminal like Arrestin_N PF00339.29 OAP62620.1 - 0.014 15.4 0.1 0.11 12.5 0.0 2.4 2 1 1 3 3 3 0 Arrestin (or S-antigen), N-terminal domain Oxidored_molyb PF00174.19 OAP62621.1 - 5.2e-48 162.9 0.0 9.3e-48 162.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 OAP62621.1 - 4.5e-20 72.1 4.4 1e-19 70.9 4.4 1.5 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Epimerase PF01370.21 OAP62622.1 - 2.3e-13 50.2 0.0 3.5e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OAP62622.1 - 1.3e-10 40.8 0.0 1.8e-10 40.3 0.0 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 OAP62622.1 - 5.7e-10 38.8 0.0 1.9e-07 30.5 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein GDP_Man_Dehyd PF16363.5 OAP62622.1 - 5.3e-06 26.1 0.0 1.1e-05 25.1 0.0 1.5 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase DUF3390 PF11870.8 OAP62622.1 - 0.05 14.0 0.0 0.23 11.9 0.0 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF3390) NmrA PF05368.13 OAP62622.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family KR PF08659.10 OAP62622.1 - 0.16 11.9 0.1 0.81 9.6 0.0 2.0 2 0 0 2 2 2 0 KR domain SNF2_N PF00176.23 OAP62623.1 - 6.6e-71 238.8 0.0 9.2e-71 238.4 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.11 OAP62623.1 - 1.8e-23 82.3 0.0 4.8e-23 80.9 0.0 1.8 2 0 0 2 2 2 1 HIRAN domain Helicase_C PF00271.31 OAP62623.1 - 2.4e-13 50.4 0.0 4.8e-13 49.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.6 OAP62623.1 - 1.3e-05 25.0 5.8 2.2e-05 24.2 5.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAP62623.1 - 0.00075 19.3 8.6 0.0015 18.4 8.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAP62623.1 - 0.00084 19.3 7.5 0.0018 18.2 7.5 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OAP62623.1 - 0.001 18.9 4.8 0.0025 17.6 4.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) UBA_4 PF14555.6 OAP62623.1 - 0.0038 17.0 0.0 0.01 15.7 0.0 1.7 1 0 0 1 1 1 1 UBA-like domain zf-RING_5 PF14634.6 OAP62623.1 - 0.0054 16.7 6.6 0.011 15.7 6.6 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 OAP62623.1 - 0.0059 16.9 7.4 0.013 15.8 7.4 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_5 PF17121.5 OAP62623.1 - 0.15 12.0 2.3 0.31 11.0 2.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OAP62623.1 - 2 8.3 6.6 9.3 6.2 6.8 2.0 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 OAP62623.1 - 2 8.6 7.7 4.5 7.5 7.7 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING SQS_PSY PF00494.19 OAP62624.1 - 3e-48 164.6 0.0 4.6e-48 164.0 0.0 1.3 1 0 0 1 1 1 1 Squalene/phytoene synthase UPF0052 PF01933.18 OAP62625.1 - 4.7e-62 209.9 0.0 6.5e-62 209.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 CorA PF01544.18 OAP62626.1 - 1e-27 97.2 6.1 7.7e-20 71.4 0.3 3.2 3 0 0 3 3 3 3 CorA-like Mg2+ transporter protein YL1 PF05764.13 OAP62626.1 - 0.0055 16.8 4.8 0.011 15.9 4.8 1.4 1 0 0 1 1 1 1 YL1 nuclear protein Methyltransf_12 PF08242.12 OAP62626.1 - 0.0086 16.8 0.0 0.024 15.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain zf-RING_UBOX PF13445.6 OAP62627.1 - 1.6e-09 37.6 4.5 2.1e-08 34.0 1.4 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OAP62627.1 - 5e-09 35.9 3.2 1.5e-08 34.3 3.5 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OAP62627.1 - 1.6e-08 34.2 3.9 1.6e-08 34.2 3.9 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAP62627.1 - 4.7e-08 32.9 5.2 9.5e-08 31.9 5.2 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 OAP62627.1 - 1.8e-07 30.9 9.7 1.1e-06 28.4 9.7 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OAP62627.1 - 3.3e-07 30.4 4.4 3.7e-06 27.0 4.8 2.1 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 OAP62627.1 - 3.7e-07 30.4 7.6 7.2e-07 29.4 7.6 1.5 1 1 0 1 1 1 1 Ring finger domain zf-Nse PF11789.8 OAP62627.1 - 0.00023 20.9 0.1 0.00052 19.8 0.1 1.6 1 1 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.6 OAP62627.1 - 0.00038 20.2 8.2 0.007 16.2 8.2 2.4 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 Rad50_zn_hook PF04423.14 OAP62627.1 - 0.0093 15.8 1.7 0.15 11.9 0.1 2.3 2 0 0 2 2 2 1 Rad50 zinc hook motif zf-rbx1 PF12678.7 OAP62627.1 - 0.1 12.9 8.7 0.42 10.9 8.7 2.1 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 OAP62627.1 - 0.11 12.6 6.2 3.9 7.6 6.2 2.3 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger FYVE PF01363.21 OAP62627.1 - 0.17 12.0 4.7 0.38 10.9 4.7 1.6 1 1 0 1 1 1 0 FYVE zinc finger zf-RING_4 PF14570.6 OAP62627.1 - 0.22 11.3 7.7 1 9.2 7.6 2.1 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 OAP62627.1 - 0.31 11.2 4.8 1.3 9.2 4.8 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_10 PF16685.5 OAP62627.1 - 0.54 10.4 4.4 0.18 12.0 1.3 1.8 2 0 0 2 2 2 0 zinc RING finger of MSL2 zf-RING_6 PF14835.6 OAP62627.1 - 0.65 9.9 7.0 3.3 7.6 4.2 2.5 2 1 0 2 2 2 0 zf-RING of BARD1-type protein Zn_Tnp_IS91 PF14319.6 OAP62627.1 - 0.67 10.0 5.4 0.13 12.3 2.0 1.7 1 1 1 2 2 2 0 Transposase zinc-binding domain DZR PF12773.7 OAP62627.1 - 1.8 8.6 7.5 52 4.0 7.5 2.4 1 1 0 1 1 1 0 Double zinc ribbon Baculo_IE-1 PF05290.11 OAP62627.1 - 3.3 7.7 5.8 7.7 6.5 5.8 1.6 1 1 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) Auto_anti-p27 PF06677.12 OAP62627.1 - 9 6.5 10.4 16 5.7 4.6 2.4 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) AMP-binding PF00501.28 OAP62628.1 - 7.3e-40 136.8 0.0 1.7e-39 135.6 0.0 1.5 1 1 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 OAP62628.1 - 3.5e-09 36.4 2.4 3.5e-09 36.4 2.4 2.1 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 OAP62628.1 - 0.0036 18.2 0.9 0.01 16.8 0.0 2.2 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain Aminotran_1_2 PF00155.21 OAP62629.1 - 9.6e-60 202.7 0.0 1.7e-59 201.8 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 OAP62629.1 - 0.015 14.6 0.0 0.022 14.0 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Aminotran_5 PF00266.19 OAP62629.1 - 0.041 12.8 0.0 0.075 12.0 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 OAP62629.1 - 0.16 10.4 0.0 0.29 9.6 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme BH4 PF02180.17 OAP62630.1 - 0.39 10.6 3.0 0.37 10.6 1.0 2.1 2 0 0 2 2 2 0 Bcl-2 homology region 4 FAA_hydrolase PF01557.18 OAP62631.1 - 5.4e-64 215.8 0.0 1.1e-63 214.9 0.0 1.5 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Abhydrolase_1 PF00561.20 OAP62631.1 - 5.1e-25 88.6 0.0 9.2e-25 87.7 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAP62631.1 - 1.8e-21 77.8 1.2 3.9e-21 76.7 1.2 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAP62631.1 - 4.2e-20 72.0 0.0 7.3e-20 71.3 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Amidohydro_1 PF01979.20 OAP62631.1 - 1.7e-14 54.0 0.6 2.5e-14 53.4 0.6 1.3 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 OAP62631.1 - 3e-08 33.6 0.3 3.6e-05 23.4 0.1 2.9 2 1 0 2 2 2 2 Amidohydrolase family Ser_hydrolase PF06821.13 OAP62631.1 - 7.9e-05 22.6 0.4 0.0079 16.1 0.1 2.9 2 1 1 3 3 3 1 Serine hydrolase Abhydrolase_4 PF08386.10 OAP62631.1 - 0.00012 22.1 0.0 0.00058 19.9 0.0 2.2 2 0 0 2 2 2 1 TAP-like protein BAAT_C PF08840.11 OAP62631.1 - 0.00074 19.5 0.0 0.0028 17.6 0.0 1.8 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Ndr PF03096.14 OAP62631.1 - 0.003 16.3 0.0 0.0047 15.7 0.0 1.3 1 0 0 1 1 1 1 Ndr family Thioesterase PF00975.20 OAP62631.1 - 0.02 15.0 0.0 0.051 13.7 0.0 1.7 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_5 PF12695.7 OAP62631.1 - 0.075 12.8 0.0 0.6 9.9 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase family DUF2437 PF10370.9 OAP62631.1 - 0.088 13.7 0.0 0.47 11.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF2437) Coilin_N PF15862.5 OAP62631.1 - 0.12 12.2 0.0 0.3 10.9 0.0 1.6 1 0 0 1 1 1 0 Coilin N-terminus Fungal_trans PF04082.18 OAP62632.1 - 8.6e-11 41.4 0.1 1.4e-10 40.7 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP62632.1 - 2.7e-07 30.6 12.8 5.5e-07 29.6 12.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TRI12 PF06609.13 OAP62633.1 - 5.4e-50 170.4 16.3 6.8e-50 170.1 16.3 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAP62633.1 - 2e-20 73.0 48.2 2e-20 73.0 48.2 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily ESSS PF10183.9 OAP62633.1 - 0.023 14.9 0.4 0.29 11.4 0.1 2.5 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) TRI12 PF06609.13 OAP62634.1 - 6.5e-53 180.1 20.4 8.5e-53 179.7 20.4 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAP62634.1 - 5.3e-31 107.8 45.0 5.4e-31 107.8 42.4 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAP62634.1 - 8.6e-11 41.3 12.7 8.6e-11 41.3 12.7 4.1 3 2 1 4 4 4 1 Sugar (and other) transporter MFS_3 PF05977.13 OAP62634.1 - 0.00075 18.0 15.0 0.0096 14.4 1.2 3.2 2 1 1 3 3 3 3 Transmembrane secretion effector Pox_A14 PF05767.12 OAP62634.1 - 0.47 10.6 5.7 1.7 8.9 0.1 3.4 2 1 1 3 3 3 0 Poxvirus virion envelope protein A14 COX6C PF02937.15 OAP62634.1 - 4.9 7.4 5.3 36 4.6 0.0 3.5 3 0 0 3 3 3 0 Cytochrome c oxidase subunit VIc Grg1 PF11034.8 OAP62636.1 - 3.1e-23 81.8 4.6 3.7e-23 81.5 4.6 1.1 1 0 0 1 1 1 1 Glucose-repressible protein Grg1 ETC_C1_NDUFA4 PF04800.12 OAP62637.1 - 1.5e-35 121.3 0.7 2.8e-35 120.4 0.7 1.4 1 0 0 1 1 1 1 ETC complex I subunit conserved region PhzC-PhzF PF02567.16 OAP62638.1 - 8e-38 130.5 0.8 3.7e-37 128.3 0.8 1.9 1 1 0 1 1 1 1 Phenazine biosynthesis-like protein Catalase PF00199.19 OAP62639.1 - 1.2e-170 567.7 0.0 1.7e-170 567.3 0.0 1.2 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 OAP62639.1 - 2.2e-18 66.2 0.1 5e-18 65.1 0.1 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive Catalase_C PF18011.1 OAP62639.1 - 2.1e-09 37.2 0.3 5.6e-09 35.8 0.3 1.7 1 0 0 1 1 1 1 C-terminal domain found in long catalases DJ-1_PfpI PF01965.24 OAP62639.1 - 2.2e-09 37.3 0.1 4.4e-09 36.4 0.1 1.5 1 0 0 1 1 1 1 DJ-1/PfpI family PQ-loop PF04193.14 OAP62640.1 - 4e-29 100.2 7.1 4.5e-18 64.8 2.1 2.5 2 0 0 2 2 2 2 PQ loop repeat HAGH_C PF16123.5 OAP62640.1 - 3.6e-20 72.3 2.4 6e-20 71.5 2.4 1.4 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 OAP62640.1 - 8.5e-11 42.2 1.1 4.7e-10 39.8 1.1 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily MtN3_slv PF03083.16 OAP62640.1 - 0.036 14.1 0.6 0.16 12.0 0.1 2.2 2 0 0 2 2 2 0 Sugar efflux transporter for intercellular exchange Lactamase_B_2 PF12706.7 OAP62640.1 - 0.088 12.3 0.4 0.23 11.0 0.4 1.8 1 1 0 1 1 1 0 Beta-lactamase superfamily domain NUC153 PF08159.12 OAP62642.1 - 2.2e-17 62.5 8.0 1.9e-14 53.1 0.4 3.9 3 0 0 3 3 3 3 NUC153 domain GDP_Man_Dehyd PF16363.5 OAP62643.1 - 9.5e-51 173.1 0.0 1.8e-50 172.2 0.0 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 OAP62643.1 - 1.6e-45 155.5 0.0 2e-45 155.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OAP62643.1 - 2.8e-17 62.6 0.0 3.9e-17 62.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 OAP62643.1 - 3.9e-13 49.2 0.0 1.5e-11 44.0 0.0 2.2 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 OAP62643.1 - 1.6e-12 47.1 0.0 2.3e-12 46.6 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 OAP62643.1 - 1.6e-07 31.0 0.0 2.5e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.12 OAP62643.1 - 1.9e-06 27.2 0.0 7.9e-05 21.9 0.0 2.3 1 1 0 1 1 1 1 Male sterility protein KR PF08659.10 OAP62643.1 - 5.2e-05 23.2 0.0 9.9e-05 22.3 0.0 1.5 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 OAP62643.1 - 0.0026 17.4 0.0 0.004 16.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NmrA PF05368.13 OAP62643.1 - 0.024 14.2 0.0 0.51 9.8 0.0 2.2 2 0 0 2 2 2 0 NmrA-like family UDPG_MGDP_dh_N PF03721.14 OAP62643.1 - 0.13 11.8 0.1 0.23 11.0 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_binding_3 PF01494.19 OAP62644.1 - 2.5e-17 63.2 0.9 2.3e-15 56.7 0.9 2.8 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 OAP62644.1 - 0.026 14.7 0.0 0.19 12.0 0.0 2.3 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain MDM10 PF12519.8 OAP62645.1 - 4.8e-131 437.8 5.5 7.8e-129 430.6 5.5 2.0 1 1 0 1 1 1 1 Mitochondrial distribution and morphology protein 10 Aa_trans PF01490.18 OAP62646.1 - 2.2e-22 79.3 35.9 2.8e-22 79.0 35.9 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein NADH_Oxid_Nqo15 PF11497.8 OAP62646.1 - 0.12 12.4 0.0 5.9 7.0 0.0 2.4 2 0 0 2 2 2 0 NADH-quinone oxidoreductase chain 15 DUF5056 PF16479.5 OAP62646.1 - 0.58 10.4 4.9 0.8 10.0 0.9 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF5056) Abhydrolase_6 PF12697.7 OAP62647.1 - 1e-18 68.8 0.4 1.2e-18 68.5 0.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAP62647.1 - 1e-06 28.6 0.0 8.5e-05 22.3 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAP62647.1 - 2.5e-05 23.7 0.0 0.00075 18.8 0.0 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 TPR_7 PF13176.6 OAP62647.1 - 0.01 15.8 0.0 0.027 14.5 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.6 OAP62647.1 - 0.17 12.2 0.0 0.59 10.5 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Abhydrolase_3 PF07859.13 OAP62648.1 - 1.2e-07 31.8 0.0 1.6e-06 28.2 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OAP62648.1 - 2.1e-06 27.4 0.0 3.7e-06 26.6 0.0 1.4 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 OAP62648.1 - 7.9e-06 25.7 0.0 1.1e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 OAP62648.1 - 1.3e-05 24.3 0.0 1.7e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Hydrolase_4 PF12146.8 OAP62648.1 - 1.4e-05 24.5 0.0 2.1e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OAP62648.1 - 0.00028 21.5 0.3 0.00068 20.3 0.3 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.28 OAP62648.1 - 0.0032 16.4 0.0 0.0055 15.6 0.0 1.4 1 1 0 1 1 1 1 Carboxylesterase family Patatin PF01734.22 OAP62648.1 - 0.078 13.1 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 Patatin-like phospholipase Pyr_redox_3 PF13738.6 OAP62649.1 - 5.9e-10 38.9 1.2 0.00045 19.6 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 OAP62649.1 - 3.6e-08 32.3 0.0 3.6e-05 22.4 0.0 2.5 3 0 0 3 3 3 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 OAP62649.1 - 8.7e-06 25.2 3.2 0.024 13.9 1.0 3.1 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAP62649.1 - 0.0005 19.3 1.1 0.058 12.5 0.0 2.6 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 OAP62649.1 - 0.018 14.3 2.3 0.018 14.3 2.3 1.5 2 0 0 2 2 2 0 FAD binding domain DUF2623 PF11115.8 OAP62649.1 - 0.056 13.5 0.1 0.15 12.2 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2623) Pyr_redox PF00070.27 OAP62649.1 - 0.26 11.9 4.0 2.4 8.8 1.2 2.7 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAP62649.1 - 0.93 8.5 5.3 1.2 8.1 3.4 1.9 2 0 0 2 2 2 0 FAD binding domain adh_short PF00106.25 OAP62650.1 - 1.1e-09 38.0 0.0 2.7e-09 36.8 0.0 1.6 1 1 1 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP62650.1 - 1.8e-07 31.0 0.1 2.6e-07 30.5 0.1 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NmrA PF05368.13 OAP62650.1 - 0.11 12.0 0.3 0.28 10.7 0.1 1.7 2 0 0 2 2 2 0 NmrA-like family 2-Hacid_dh_C PF02826.19 OAP62650.1 - 0.14 11.5 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain adh_short_C2 PF13561.6 OAP62651.1 - 6.4e-50 169.9 2.7 8.1e-50 169.6 2.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP62651.1 - 4e-41 140.6 4.4 5.3e-41 140.2 4.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAP62651.1 - 3.4e-08 33.6 1.6 5.1e-08 33.0 1.6 1.2 1 0 0 1 1 1 1 KR domain YjeF_N PF03853.15 OAP62651.1 - 0.002 18.0 0.3 0.0033 17.3 0.3 1.3 1 0 0 1 1 1 1 YjeF-related protein N-terminus CbiA PF01656.23 OAP62651.1 - 0.0036 17.3 0.1 0.0069 16.4 0.1 1.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Dak1_2 PF13684.6 OAP62651.1 - 0.01 14.9 0.2 0.014 14.5 0.2 1.3 1 0 0 1 1 1 0 Dihydroxyacetone kinase family Rossmann-like PF10727.9 OAP62651.1 - 0.03 14.2 0.4 0.055 13.3 0.4 1.5 1 0 0 1 1 1 0 Rossmann-like domain Sacchrp_dh_NADP PF03435.18 OAP62651.1 - 0.032 14.5 0.5 0.055 13.7 0.5 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain 2-Hacid_dh_C PF02826.19 OAP62651.1 - 0.037 13.4 1.9 0.072 12.5 1.1 1.8 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 OAP62651.1 - 0.073 12.5 0.2 0.21 10.9 0.1 1.8 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase DFP PF04127.15 OAP62651.1 - 0.2 11.4 4.5 1.3 8.8 4.5 2.0 1 1 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein 3HCDH_N PF02737.18 OAP62651.1 - 1.3 8.9 7.1 0.064 13.1 1.6 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 OAP62652.1 - 4.7e-23 82.0 0.0 8.5e-23 81.1 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain SE PF08491.10 OAP62652.1 - 0.0068 15.5 0.0 0.012 14.7 0.0 1.3 1 0 0 1 1 1 1 Squalene epoxidase NAD_binding_8 PF13450.6 OAP62652.1 - 0.014 15.6 0.0 0.04 14.2 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAP62652.1 - 0.16 11.2 0.3 2.5 7.3 0.1 2.2 1 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AraC_binding PF02311.19 OAP62653.1 - 0.0045 16.9 0.0 0.01 15.7 0.0 1.5 2 0 0 2 2 2 1 AraC-like ligand binding domain Cupin_2 PF07883.11 OAP62653.1 - 0.026 14.2 0.0 0.048 13.4 0.0 1.5 1 0 0 1 1 1 0 Cupin domain DUF4570 PF15134.6 OAP62654.1 - 0.09 12.8 0.8 0.21 11.6 0.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4570) IF-2B PF01008.17 OAP62656.1 - 2.4e-16 59.8 0.9 2.3e-09 36.9 0.0 2.3 2 0 0 2 2 2 2 Initiation factor 2 subunit family NUDIX PF00293.28 OAP62656.1 - 2.8e-08 33.9 0.1 7.1e-08 32.6 0.1 1.7 1 0 0 1 1 1 1 NUDIX domain Sugar_tr PF00083.24 OAP62657.1 - 1.8e-120 402.9 22.5 2.1e-120 402.6 22.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP62657.1 - 3.3e-25 88.7 46.3 7.3e-21 74.5 20.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily SecA_DEAD PF07517.14 OAP62657.1 - 0.11 11.7 0.6 0.19 11.0 0.6 1.2 1 0 0 1 1 1 0 SecA DEAD-like domain Zn_clus PF00172.18 OAP62658.1 - 6.3e-06 26.2 11.6 1.1e-05 25.4 11.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 OAP62659.1 - 2e-25 89.5 20.5 2e-25 89.5 20.5 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF21 PF01595.20 OAP62659.1 - 1.9 8.1 9.9 6.8 6.4 0.8 2.6 2 0 0 2 2 2 0 Cyclin M transmembrane N-terminal domain Amidohydro_3 PF07969.11 OAP62660.1 - 5.9e-77 260.1 5.2 6.8e-77 259.9 5.2 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 OAP62660.1 - 2.5e-15 56.7 0.0 5.1e-10 39.2 0.0 2.5 2 1 0 2 2 2 2 Amidohydrolase family Ank_2 PF12796.7 OAP62660.1 - 0.11 13.1 0.0 0.25 11.9 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Asp PF00026.23 OAP62661.1 - 1.8e-69 234.6 8.8 2.2e-69 234.3 8.8 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OAP62661.1 - 1.4e-11 44.9 4.7 1.4e-05 25.4 0.1 3.0 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 OAP62661.1 - 4.5e-05 24.0 1.1 0.05 14.3 0.2 3.5 2 1 0 2 2 2 2 Aspartyl protease EpmC PF04315.12 OAP62661.1 - 0.13 12.0 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Elongation factor P hydroxylase zf-C3HC4_3 PF13920.6 OAP62662.1 - 5.6e-09 35.7 11.8 9e-09 35.1 11.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) 7tm_1 PF00001.21 OAP62662.1 - 0.023 14.0 0.0 0.041 13.2 0.0 1.4 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Prok-RING_4 PF14447.6 OAP62662.1 - 0.64 9.9 12.4 1.2 9.1 12.4 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 DUF4449 PF14613.6 OAP62664.1 - 3.6e-64 215.8 4.3 3.6e-64 215.8 4.3 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF4449) PHA_gran_rgn PF09650.10 OAP62664.1 - 0.011 16.0 0.2 0.039 14.2 0.2 2.0 1 0 0 1 1 1 0 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) Prp18 PF02840.15 OAP62664.1 - 0.75 9.8 0.0 0.75 9.8 0.0 3.5 3 1 1 4 4 4 0 Prp18 domain DUF4211 PF13926.6 OAP62665.1 - 7.8e-37 126.5 0.1 4e-36 124.2 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4211) SPT6_acidic PF14632.6 OAP62665.1 - 0.0019 18.7 5.9 0.0019 18.7 5.9 5.5 4 1 1 6 6 6 2 Acidic N-terminal SPT6 DNA_pol_alpha_N PF12254.8 OAP62665.1 - 7.4 6.7 15.7 5.7 7.1 0.4 4.7 5 0 0 5 5 5 0 DNA polymerase alpha subunit p180 N terminal Tom22 PF04281.13 OAP62666.1 - 1.2e-43 148.2 0.1 1.4e-43 148.0 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 TIM PF00121.18 OAP62667.1 - 1.7e-90 302.6 0.0 2e-90 302.5 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase CutC PF03932.14 OAP62667.1 - 0.04 13.4 0.0 0.063 12.8 0.0 1.3 1 0 0 1 1 1 0 CutC family OB_NTP_bind PF07717.16 OAP62668.1 - 1e-21 77.1 0.0 3e-21 75.5 0.0 1.8 2 0 0 2 2 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 OAP62668.1 - 9.7e-19 67.6 0.1 2.8e-18 66.2 0.0 1.8 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 OAP62668.1 - 1.7e-11 44.4 0.0 6.1e-11 42.7 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 OAP62668.1 - 9.2e-07 28.8 0.2 1.8e-06 27.8 0.2 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 OAP62668.1 - 3.4e-06 27.4 0.1 1.1e-05 25.8 0.1 1.8 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 OAP62668.1 - 0.00014 21.6 0.1 0.0004 20.1 0.1 1.7 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain Flavi_DEAD PF07652.14 OAP62668.1 - 0.00053 20.0 0.1 0.0011 18.9 0.1 1.5 1 0 0 1 1 1 1 Flavivirus DEAD domain AAA_19 PF13245.6 OAP62668.1 - 0.0021 18.4 0.1 0.0043 17.4 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 OAP62668.1 - 0.0048 16.6 0.0 0.0078 15.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 OAP62668.1 - 0.014 15.9 0.0 0.027 15.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 OAP62668.1 - 0.017 14.2 0.0 0.033 13.3 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_7 PF12775.7 OAP62668.1 - 0.03 13.8 0.0 0.081 12.4 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region RCR PF12273.8 OAP62669.1 - 0.00083 20.0 0.0 0.0016 19.1 0.0 1.5 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red EphA2_TM PF14575.6 OAP62669.1 - 0.026 15.4 0.0 0.049 14.5 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain ECSCR PF15820.5 OAP62669.1 - 0.14 12.0 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator TMEM154 PF15102.6 OAP62669.1 - 2 8.3 3.0 6.4 6.7 3.0 1.7 1 1 0 1 1 1 0 TMEM154 protein family tRNA_U5-meth_tr PF05958.11 OAP62670.1 - 1.7e-15 56.9 0.0 6.7e-15 54.9 0.0 1.9 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase PrmA PF06325.13 OAP62670.1 - 2.9e-06 26.9 0.0 4.4e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_15 PF09445.10 OAP62670.1 - 2.5e-05 23.9 0.0 4e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_25 PF13649.6 OAP62670.1 - 6.1e-05 23.7 0.0 0.00015 22.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAP62670.1 - 0.0013 18.6 0.0 0.0024 17.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAP62670.1 - 0.0029 18.2 0.0 0.0069 17.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 OAP62670.1 - 0.041 13.5 0.0 0.085 12.5 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Met_10 PF02475.16 OAP62670.1 - 0.083 12.6 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_23 PF13489.6 OAP62670.1 - 0.11 12.3 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Glyco_hydro_31 PF01055.26 OAP62671.1 - 0.032 13.4 0.0 0.054 12.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 31 Actin PF00022.19 OAP62672.1 - 5.2e-87 292.1 0.0 2.2e-53 181.4 0.0 2.0 1 1 1 2 2 2 2 Actin MreB_Mbl PF06723.13 OAP62672.1 - 0.033 13.0 0.0 1 8.1 0.0 2.2 2 0 0 2 2 2 0 MreB/Mbl protein M_domain PF12938.7 OAP62672.1 - 0.69 9.7 1.7 1.1 9.0 1.7 1.3 1 0 0 1 1 1 0 M domain of GW182 Asparaginase_2 PF01112.18 OAP62673.1 - 3.2e-47 161.1 0.7 4.6e-33 114.5 0.0 2.2 2 0 0 2 2 2 2 Asparaginase EccE PF11203.8 OAP62673.1 - 0.0093 16.3 0.1 0.027 14.8 0.1 1.7 1 0 0 1 1 1 1 Putative type VII ESX secretion system translocon, EccE Tfb4 PF03850.14 OAP62674.1 - 4.8e-89 298.5 0.1 2.6e-53 181.3 0.0 2.5 2 1 0 2 2 2 2 Transcription factor Tfb4 UNC45-central PF11701.8 OAP62675.1 - 5.6e-38 130.3 0.7 2.6e-37 128.1 0.0 2.6 4 0 0 4 4 4 1 Myosin-binding striated muscle assembly central LytR_C PF13399.6 OAP62675.1 - 0.093 13.7 0.1 0.53 11.3 0.1 2.4 1 0 0 1 1 1 0 LytR cell envelope-related transcriptional attenuator Arm PF00514.23 OAP62675.1 - 0.11 12.6 10.5 9.5 6.4 0.0 5.9 7 0 0 7 7 7 0 Armadillo/beta-catenin-like repeat SUIM_assoc PF16619.5 OAP62676.1 - 0.14 12.2 7.3 0.28 11.3 0.4 2.8 1 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 PKcGMP_CC PF16808.5 OAP62676.1 - 0.26 11.2 3.6 0.64 9.9 0.1 2.6 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Syntaxin_2 PF14523.6 OAP62676.1 - 8.2 6.9 13.5 1.1 9.7 7.2 2.5 2 0 0 2 2 2 0 Syntaxin-like protein BLOC1_2 PF10046.9 OAP62676.1 - 8.9 6.7 9.7 0.8 10.0 1.7 3.0 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DSPc PF00782.20 OAP62678.1 - 1.2e-26 93.1 0.0 4.2e-20 71.9 0.0 2.3 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 OAP62678.1 - 8.9e-05 22.2 0.0 0.0022 17.6 0.0 2.2 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Cupin_8 PF13621.6 OAP62679.1 - 1.3e-29 103.6 0.0 2.5e-29 102.8 0.0 1.4 1 0 0 1 1 1 1 Cupin-like domain LCM PF04072.14 OAP62679.1 - 1.1e-18 67.9 0.0 4.1e-18 66.0 0.0 1.8 2 0 0 2 2 2 1 Leucine carboxyl methyltransferase Kelch_4 PF13418.6 OAP62679.1 - 1.2e-07 31.6 9.4 1.3e-06 28.2 0.0 5.0 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_5 PF13854.6 OAP62679.1 - 0.0045 16.9 0.1 0.33 11.0 0.0 3.0 2 0 0 2 2 2 1 Kelch motif Kelch_2 PF07646.15 OAP62679.1 - 0.026 14.5 0.4 12 6.0 0.0 2.9 2 0 0 2 2 2 0 Kelch motif Kelch_3 PF13415.6 OAP62679.1 - 0.17 12.2 0.9 7.7 6.9 0.1 3.8 3 0 0 3 3 3 0 Galactose oxidase, central domain TAP42 PF04177.12 OAP62680.1 - 1.8e-101 339.4 0.9 2.1e-101 339.3 0.9 1.0 1 0 0 1 1 1 1 TAP42-like family Cytochrom_B562 PF07361.11 OAP62680.1 - 0.0026 18.4 1.2 0.0041 17.7 0.2 1.9 2 0 0 2 2 2 1 Cytochrome b562 eIF-4B PF06273.11 OAP62680.1 - 0.011 14.8 0.4 0.017 14.2 0.4 1.2 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B HisKA PF00512.25 OAP62680.1 - 0.14 12.2 1.1 0.32 11.1 0.1 2.2 2 0 0 2 2 2 0 His Kinase A (phospho-acceptor) domain DUF4011 PF13195.6 OAP62680.1 - 0.38 10.7 3.2 0.61 10.0 3.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4011) Porphobil_deam PF01379.20 OAP62681.1 - 2.3e-69 233.0 0.0 3.2e-69 232.5 0.0 1.2 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 OAP62681.1 - 2.1e-15 56.8 0.1 3.7e-15 56.1 0.1 1.4 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain Lon_C PF05362.13 OAP62682.1 - 1.9e-73 246.4 0.8 1.4e-72 243.6 0.8 2.3 2 0 0 2 2 2 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 OAP62682.1 - 8.1e-29 101.0 0.0 1.9e-28 99.7 0.0 1.7 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 OAP62682.1 - 3.1e-23 82.6 0.0 5.7e-22 78.6 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 OAP62682.1 - 1.1e-07 31.9 0.0 2.8e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.6 OAP62682.1 - 5.6e-07 29.4 0.0 1.3e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_16 PF13191.6 OAP62682.1 - 1e-05 26.0 0.1 5.4e-05 23.6 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.17 OAP62682.1 - 3.3e-05 23.7 0.0 7.8e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.13 OAP62682.1 - 4.5e-05 22.8 0.0 0.0001 21.6 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_3 PF07726.11 OAP62682.1 - 0.00017 21.5 0.0 0.00062 19.6 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OAP62682.1 - 0.00026 21.3 0.1 0.0082 16.4 0.1 3.1 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.12 OAP62682.1 - 0.00047 19.9 0.0 0.0024 17.6 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 OAP62682.1 - 0.0012 19.0 0.0 0.0041 17.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) Birna_VP4 PF01768.16 OAP62682.1 - 0.0047 16.8 0.1 0.012 15.4 0.1 1.6 1 0 0 1 1 1 1 Birnavirus VP4 protein AAA_33 PF13671.6 OAP62682.1 - 0.018 15.2 0.0 0.049 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 OAP62682.1 - 0.02 14.4 0.0 0.044 13.2 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.12 OAP62682.1 - 0.022 14.7 0.1 0.14 12.0 0.0 2.4 3 0 0 3 3 3 0 NACHT domain AAA_25 PF13481.6 OAP62682.1 - 0.025 14.1 0.0 0.061 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 OAP62682.1 - 0.026 14.0 0.0 0.05 13.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_PrkA PF08298.11 OAP62682.1 - 0.048 12.6 0.1 0.53 9.1 0.1 2.1 2 0 0 2 2 2 0 PrkA AAA domain Mg_chelatase PF01078.21 OAP62682.1 - 0.05 13.0 0.1 0.12 11.8 0.1 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 OAP62682.1 - 0.061 13.9 0.3 0.22 12.1 0.0 2.1 2 0 0 2 2 1 0 AAA domain Rad17 PF03215.15 OAP62682.1 - 0.075 13.0 0.0 0.22 11.4 0.0 1.7 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_23 PF13476.6 OAP62682.1 - 0.078 13.5 0.0 0.078 13.5 0.0 2.6 1 1 0 2 2 1 0 AAA domain RNA_helicase PF00910.22 OAP62682.1 - 0.081 13.3 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.27 OAP62682.1 - 0.089 13.3 0.1 0.48 10.9 0.0 2.2 2 0 0 2 2 2 0 ABC transporter TniB PF05621.11 OAP62682.1 - 0.097 12.1 0.0 0.28 10.6 0.0 1.7 2 0 0 2 2 1 0 Bacterial TniB protein AAA_24 PF13479.6 OAP62682.1 - 0.11 12.2 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 OAP62682.1 - 0.11 12.5 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 OAP62682.1 - 0.12 12.2 1.9 0.15 11.9 0.1 1.9 1 1 1 2 2 2 0 AAA domain TsaE PF02367.17 OAP62682.1 - 0.18 11.8 0.0 0.39 10.7 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Laps PF10169.9 OAP62682.1 - 2.1 8.9 3.9 3.1 8.4 0.1 2.6 1 1 1 2 2 2 0 Learning-associated protein APG6_N PF17675.1 OAP62682.1 - 3.3 8.2 6.5 11 6.5 6.5 1.9 1 1 0 1 1 1 0 Apg6 coiled-coil region Ribosomal_L23 PF00276.20 OAP62683.1 - 9.3e-10 38.7 0.0 1.8e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L23 RPN1_RPN2_N PF17781.1 OAP62684.1 - 1.1e-117 392.8 1.7 2.1e-117 391.9 1.7 1.5 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 OAP62684.1 - 1.4e-28 98.7 0.0 2.6e-28 97.8 0.0 1.5 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 OAP62684.1 - 5.8e-21 73.8 13.8 1.7e-05 25.0 0.1 8.6 9 1 0 9 9 9 4 Proteasome/cyclosome repeat HEAT_2 PF13646.6 OAP62684.1 - 6.9e-07 29.6 0.4 0.016 15.6 0.1 4.6 4 1 1 5 5 5 2 HEAT repeats IFRD PF05004.13 OAP62684.1 - 0.0037 16.4 0.0 0.025 13.7 0.0 2.4 1 1 0 1 1 1 1 Interferon-related developmental regulator (IFRD) TPR_12 PF13424.6 OAP62684.1 - 0.061 13.6 1.7 5.9 7.3 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat MFS_1 PF07690.16 OAP62685.1 - 1.9e-16 60.0 14.8 4.7e-16 58.7 14.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.13 OAP62685.1 - 0.0079 15.7 7.4 0.01 15.4 3.4 2.4 2 1 0 2 2 2 1 Nodulin-like DUF3464 PF11947.8 OAP62685.1 - 0.14 11.9 0.4 0.35 10.6 0.4 1.6 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 SPT6_acidic PF14632.6 OAP62685.1 - 0.25 11.9 3.9 4.3 8.0 0.2 2.3 2 0 0 2 2 2 0 Acidic N-terminal SPT6 EMP70 PF02990.16 OAP62685.1 - 1 8.0 6.1 0.091 11.4 0.5 1.9 2 0 0 2 2 2 0 Endomembrane protein 70 Transglut_core PF01841.19 OAP62686.1 - 8e-12 45.6 0.0 1.8e-11 44.4 0.0 1.7 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF553 PF04473.12 OAP62686.1 - 0.043 13.4 0.0 1.6 8.3 0.0 2.5 2 1 0 2 2 2 0 Transglutaminase-like domain NmrA PF05368.13 OAP62687.1 - 2.4e-21 76.3 0.0 3.1e-21 76.0 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAP62687.1 - 3e-16 59.9 0.0 5.8e-16 58.9 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Shikimate_DH PF01488.20 OAP62687.1 - 1.1e-05 25.5 0.2 2.1e-05 24.6 0.1 1.5 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Semialdhyde_dh PF01118.24 OAP62687.1 - 3.3e-05 24.3 0.0 5.6e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 OAP62687.1 - 7.8e-05 22.9 0.0 0.00014 22.2 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain DapB_N PF01113.20 OAP62687.1 - 0.00013 22.1 0.5 0.00032 20.8 0.1 1.8 2 1 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus Epimerase PF01370.21 OAP62687.1 - 0.0023 17.4 0.0 0.0038 16.7 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 OAP62687.1 - 0.0042 16.3 0.0 0.0061 15.8 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein GFO_IDH_MocA PF01408.22 OAP62687.1 - 0.006 17.4 0.0 0.01 16.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DXP_reductoisom PF02670.16 OAP62687.1 - 0.029 15.1 0.1 0.28 11.9 0.0 2.2 1 1 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase NAD_binding_3 PF03447.16 OAP62687.1 - 0.03 15.0 0.0 0.07 13.8 0.0 1.5 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 OAP62687.1 - 0.12 11.4 0.0 0.2 10.6 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family IBR PF01485.21 OAP62688.1 - 2.1e-13 50.3 31.9 5.3e-07 29.8 14.1 3.5 2 1 1 3 3 3 3 IBR domain, a half RING-finger domain zf-C3HC4_2 PF13923.6 OAP62688.1 - 0.00014 21.6 3.3 0.00014 21.6 3.3 4.5 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAP62688.1 - 0.00016 21.6 7.9 0.00016 21.6 7.9 3.2 2 1 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 OAP62688.1 - 0.00037 20.7 7.1 0.00037 20.7 7.1 4.0 3 1 1 4 4 4 1 Ring finger domain zf-RING_5 PF14634.6 OAP62688.1 - 0.0016 18.3 7.2 0.0016 18.3 7.2 3.9 2 1 2 4 4 4 1 zinc-RING finger domain zf-ribbon_3 PF13248.6 OAP62688.1 - 0.0034 16.7 1.6 0.09 12.2 0.0 2.9 2 0 0 2 2 2 1 zinc-ribbon domain zf-C3HC4 PF00097.25 OAP62688.1 - 0.0039 17.0 6.4 0.0039 17.0 6.4 3.8 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OAP62688.1 - 0.026 14.7 5.9 0.026 14.7 5.9 3.8 3 2 0 3 3 3 0 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 OAP62688.1 - 0.034 13.9 4.7 0.034 13.9 4.7 2.8 3 0 0 3 3 3 0 RING-like zinc finger zinc_ribbon_2 PF13240.6 OAP62688.1 - 0.21 11.4 0.0 0.21 11.4 0.0 3.7 3 0 0 3 3 3 0 zinc-ribbon domain Sugar_tr PF00083.24 OAP62689.1 - 3.9e-90 302.9 31.2 2.2e-88 297.1 31.2 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP62689.1 - 1.2e-21 77.0 30.0 1.2e-21 77.0 30.0 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily OppC_N PF12911.7 OAP62689.1 - 0.53 10.3 0.0 0.53 10.3 0.0 4.0 5 0 0 5 5 5 0 N-terminal TM domain of oligopeptide transport permease C CPP1-like PF11833.8 OAP62689.1 - 1.5 8.4 5.1 0.24 11.0 0.5 2.0 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like adh_short_C2 PF13561.6 OAP62690.1 - 9e-47 159.6 3.7 1.2e-45 156.0 3.7 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP62690.1 - 3.1e-37 127.9 1.7 1.7e-36 125.5 1.7 1.9 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAP62690.1 - 7.4e-09 35.8 0.5 1.1e-08 35.2 0.5 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAP62690.1 - 1.4e-07 31.2 0.0 2.5e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 OAP62690.1 - 9.6e-07 28.9 0.4 1.3e-06 28.4 0.4 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 OAP62690.1 - 2.5e-05 24.5 0.2 4.6e-05 23.7 0.2 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain 3Beta_HSD PF01073.19 OAP62690.1 - 4.9e-05 22.5 0.2 7.5e-05 21.9 0.2 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 OAP62690.1 - 0.00041 19.9 0.1 0.0006 19.3 0.1 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 OAP62690.1 - 0.0088 15.2 0.1 0.015 14.5 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 OAP62690.1 - 0.021 14.7 0.9 0.036 14.0 0.9 1.4 1 0 0 1 1 1 0 NAD(P)H-binding F420_oxidored PF03807.17 OAP62690.1 - 0.023 15.3 0.2 0.043 14.4 0.2 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent UDPG_MGDP_dh_N PF03721.14 OAP62690.1 - 0.028 14.0 0.0 0.04 13.5 0.0 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AAA_31 PF13614.6 OAP62690.1 - 0.031 14.2 0.2 0.047 13.6 0.2 1.2 1 0 0 1 1 1 0 AAA domain TrkA_N PF02254.18 OAP62690.1 - 0.037 14.3 0.1 0.062 13.6 0.1 1.3 1 0 0 1 1 1 0 TrkA-N domain Toxin_10 PF05431.11 OAP62690.1 - 0.085 12.3 0.3 0.21 11.0 0.4 1.6 2 0 0 2 2 2 0 Insecticidal Crystal Toxin, P42 Urocanase PF01175.18 OAP62690.1 - 0.088 12.4 0.1 0.13 11.9 0.1 1.2 1 0 0 1 1 1 0 Urocanase Rossmann-like domain YjeF_N PF03853.15 OAP62690.1 - 0.088 12.7 0.1 0.16 11.9 0.1 1.4 1 0 0 1 1 1 0 YjeF-related protein N-terminus NAD_binding_8 PF13450.6 OAP62690.1 - 0.1 12.8 0.0 0.23 11.7 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain 2-Hacid_dh_C PF02826.19 OAP62690.1 - 0.15 11.4 0.1 0.27 10.6 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 OAP62691.1 - 6.5e-13 48.6 0.0 6.6e-12 45.3 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 OAP62691.1 - 2.5e-11 42.7 0.0 1e-10 40.7 0.0 1.8 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 OAP62691.1 - 7.1e-11 41.9 0.0 4.2e-10 39.3 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAP62691.1 - 2.3e-07 31.0 0.0 1.8e-06 28.1 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 OAP62691.1 - 2e-05 24.6 0.3 0.017 15.1 0.2 3.7 3 1 0 3 3 3 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 OAP62691.1 - 0.00067 18.9 0.0 0.021 14.0 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) 2-Hacid_dh_C PF02826.19 OAP62691.1 - 0.01 15.2 0.0 0.025 14.0 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DAO PF01266.24 OAP62691.1 - 0.011 15.4 2.2 7.5 6.0 0.1 3.7 2 1 1 3 3 3 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 OAP62691.1 - 0.017 15.6 0.1 4.5 7.9 0.2 3.2 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 OAP62691.1 - 0.038 14.4 0.0 4.7 7.7 0.0 2.6 3 0 0 3 3 2 0 Putative NAD(P)-binding FAD_binding_2 PF00890.24 OAP62691.1 - 0.072 12.2 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain FAD_binding_3 PF01494.19 OAP62691.1 - 0.17 11.1 0.1 7.7 5.7 0.2 2.2 1 1 1 2 2 2 0 FAD binding domain Rick_17kDa_Anti PF05433.15 OAP62692.1 - 0.0039 17.0 7.0 0.0039 17.0 7.0 1.8 2 0 0 2 2 2 1 Glycine zipper 2TM domain DUF456 PF04306.13 OAP62692.1 - 0.12 12.6 0.4 0.18 12.1 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF456) Amidase PF01425.21 OAP62693.1 - 6.9e-100 335.1 0.0 1e-99 334.6 0.0 1.2 1 0 0 1 1 1 1 Amidase UPF0180 PF03698.13 OAP62693.1 - 0.16 12.2 0.0 0.35 11.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0180) Citrate_synt PF00285.21 OAP62694.1 - 1.5e-20 73.6 0.0 6.3e-17 61.7 0.0 3.0 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain CoA_binding PF02629.19 OAP62694.1 - 9.2e-19 67.9 0.0 2e-18 66.9 0.0 1.6 1 0 0 1 1 1 1 CoA binding domain Ligase_CoA PF00549.19 OAP62694.1 - 8e-16 58.2 0.0 1.3e-15 57.6 0.0 1.3 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 OAP62694.1 - 4.5e-05 23.3 0.0 0.00018 21.3 0.0 1.9 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain Citrate_bind PF16114.5 OAP62695.1 - 1.1e-88 295.4 0.0 1.6e-88 294.9 0.0 1.2 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding ATP-grasp_2 PF08442.10 OAP62695.1 - 1.6e-07 31.1 0.0 2.4e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain Reovirus_M2 PF05993.12 OAP62695.1 - 0.063 11.4 0.1 0.092 10.8 0.1 1.1 1 0 0 1 1 1 0 Reovirus major virion structural protein Mu-1/Mu-1C (M2) DNA_pol_delta_4 PF04081.13 OAP62696.1 - 2.8e-36 124.8 12.0 4.3e-35 120.9 12.0 2.1 1 1 0 1 1 1 1 DNA polymerase delta, subunit 4 Pkinase PF00069.25 OAP62697.1 - 1.8e-48 165.2 0.0 2.7e-48 164.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP62697.1 - 5.4e-23 81.6 0.0 7.1e-23 81.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAP62697.1 - 4.2e-06 25.8 0.0 6.8e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase FHA PF00498.26 OAP62697.1 - 0.0015 18.8 0.0 0.0038 17.5 0.0 1.7 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.6 OAP62697.1 - 0.014 14.7 0.1 0.91 8.8 0.0 2.3 1 1 0 2 2 2 0 Kinase-like APH PF01636.23 OAP62697.1 - 0.071 13.0 0.1 0.32 10.9 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.22 OAP62697.1 - 0.21 11.2 1.1 0.45 10.1 1.1 1.5 1 1 0 1 1 1 0 RIO1 family Voltage_CLC PF00654.20 OAP62699.1 - 9.4e-90 301.4 23.1 9.4e-90 301.4 23.1 1.7 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 OAP62699.1 - 5.3e-11 42.8 0.1 9.4e-06 26.0 0.0 2.7 2 0 0 2 2 2 2 CBS domain CBFD_NFYB_HMF PF00808.23 OAP62700.1 - 1.9e-12 47.3 0.8 2e-11 44.0 0.8 2.2 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 OAP62700.1 - 0.012 16.0 0.3 0.012 16.0 0.3 1.7 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 TAFII28 PF04719.14 OAP62700.1 - 0.014 15.5 0.1 0.028 14.5 0.1 1.4 1 0 0 1 1 1 0 hTAFII28-like protein conserved region Pkinase PF00069.25 OAP62701.1 - 6e-15 55.3 0.0 1.4e-14 54.1 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP62701.1 - 0.02 14.2 0.0 0.054 12.8 0.0 1.7 1 0 0 1 1 1 0 Protein tyrosine kinase CorA PF01544.18 OAP62702.1 - 1.6e-07 31.0 1.4 2.6e-07 30.3 1.4 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein CR6_interact PF10147.9 OAP62702.1 - 0.12 12.0 0.7 0.28 10.9 0.7 1.6 1 0 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 DUF4527 PF15030.6 OAP62702.1 - 0.15 11.5 0.4 0.39 10.1 0.2 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF4527) DUF5121 PF17165.4 OAP62704.1 - 0.29 11.6 0.7 36 4.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5121) Methyltransf_11 PF08241.12 OAP62705.1 - 2.7e-19 69.6 0.0 4.5e-19 68.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAP62705.1 - 3.6e-18 65.9 0.0 5.4e-18 65.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAP62705.1 - 4.5e-18 65.8 0.0 8.4e-18 64.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAP62705.1 - 7.5e-18 64.8 0.0 1.1e-17 64.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 OAP62705.1 - 1.6e-14 53.9 0.0 2.1e-14 53.5 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 OAP62705.1 - 2.7e-14 53.7 0.0 4.6e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAP62705.1 - 1.3e-09 37.8 0.0 4.8e-08 32.6 0.0 2.1 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 OAP62705.1 - 3.4e-07 30.2 0.0 4.6e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.7 OAP62705.1 - 1.2e-06 28.5 0.0 2.2e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OAP62705.1 - 4.1e-06 26.4 0.0 6.1e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain MetW PF07021.12 OAP62705.1 - 1.4e-05 24.8 0.0 2e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW TPMT PF05724.11 OAP62705.1 - 2.3e-05 24.2 0.0 4e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_9 PF08003.11 OAP62705.1 - 2.8e-05 23.2 0.0 4.4e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) PrmA PF06325.13 OAP62705.1 - 7.2e-05 22.3 0.0 0.00011 21.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_15 PF09445.10 OAP62705.1 - 0.0005 19.7 0.0 0.00065 19.3 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_32 PF13679.6 OAP62705.1 - 0.00068 19.7 0.0 0.00098 19.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 OAP62705.1 - 0.0036 17.1 0.0 0.0051 16.6 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein TrmK PF04816.12 OAP62705.1 - 0.0051 16.4 0.0 0.0084 15.7 0.0 1.3 1 0 0 1 1 1 1 tRNA (adenine(22)-N(1))-methyltransferase UPF0020 PF01170.18 OAP62705.1 - 0.0052 16.5 0.0 0.013 15.2 0.0 1.6 1 1 1 2 2 2 1 Putative RNA methylase family UPF0020 N2227 PF07942.12 OAP62705.1 - 0.019 14.1 0.0 3 6.9 0.0 2.1 1 1 1 2 2 2 0 N2227-like protein Methyltransf_24 PF13578.6 OAP62705.1 - 0.043 14.8 0.0 0.085 13.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain GCD14 PF08704.10 OAP62705.1 - 0.15 11.7 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Methyltransf_16 PF10294.9 OAP62705.1 - 0.15 11.7 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase TRM PF02005.16 OAP62705.1 - 0.16 11.1 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase TehB PF03848.14 OAP62705.1 - 0.16 11.4 0.0 0.24 10.8 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB Rieske PF00355.26 OAP62706.1 - 9.2e-12 44.7 0.0 1.6e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.14 OAP62706.1 - 4e-11 43.2 0.1 1e-10 41.9 0.1 1.7 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region She9_MDM33 PF05546.11 OAP62707.1 - 4.7e-86 287.6 6.1 9.6e-86 286.6 6.1 1.5 1 0 0 1 1 1 1 She9 / Mdm33 family DUF3818 PF12825.7 OAP62707.1 - 0.052 12.6 0.4 0.098 11.7 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function in PX-proteins (DUF3818) Alpha_L_fucos PF01120.17 OAP62707.1 - 0.056 12.9 0.1 0.097 12.1 0.1 1.4 1 0 0 1 1 1 0 Alpha-L-fucosidase Spc7 PF08317.11 OAP62707.1 - 0.073 11.9 0.1 0.073 11.9 0.1 2.6 2 1 0 2 2 2 0 Spc7 kinetochore protein Uso1_p115_C PF04871.13 OAP62707.1 - 0.39 11.1 0.0 0.39 11.1 0.0 3.4 3 0 0 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region TBCA PF02970.16 OAP62707.1 - 1.3 9.4 8.8 0.63 10.4 0.2 3.4 3 1 0 3 3 3 0 Tubulin binding cofactor A PsbH PF00737.20 OAP62707.1 - 3.4 7.5 7.6 0.17 11.6 1.4 1.8 2 0 0 2 2 2 0 Photosystem II 10 kDa phosphoprotein HAD PF12710.7 OAP62708.1 - 7.7e-17 62.3 0.1 1.2e-16 61.7 0.1 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 OAP62708.1 - 0.00044 19.7 0.0 0.0038 16.7 0.0 2.0 1 1 0 1 1 1 1 Putative Phosphatase UMPH-1 PF05822.12 OAP62708.1 - 0.0027 17.3 0.0 0.007 15.9 0.0 1.7 1 1 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) p450 PF00067.22 OAP62709.1 - 1.3e-68 231.9 0.0 1.6e-68 231.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 YiiD_C PF09500.10 OAP62709.1 - 0.098 12.5 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Putative thioesterase (yiiD_Cterm) SUIM_assoc PF16619.5 OAP62709.1 - 0.12 12.4 0.2 17 5.6 0.1 2.7 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 GFA PF04828.14 OAP62710.1 - 3.9e-15 55.9 0.6 5.9e-15 55.4 0.6 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Nudix_N_2 PF14803.6 OAP62710.1 - 0.038 13.9 0.1 0.038 13.9 0.1 2.3 3 0 0 3 3 3 0 Nudix N-terminal DUF2769 PF10967.8 OAP62710.1 - 2.7 8.7 8.2 2.1 9.1 0.8 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2769) adh_short PF00106.25 OAP62711.1 - 1.4e-13 50.7 0.0 1.7e-12 47.2 0.0 2.2 1 1 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 OAP62711.1 - 3.5e-07 29.9 0.0 5.9e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 OAP62711.1 - 8.5e-05 22.5 0.0 0.00016 21.6 0.0 1.5 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 OAP62711.1 - 0.00014 21.5 0.0 0.0008 19.0 0.0 2.2 2 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase GDP_Man_Dehyd PF16363.5 OAP62711.1 - 0.0067 15.9 0.0 1 8.7 0.0 2.3 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase Pyr_redox_3 PF13738.6 OAP62711.1 - 0.076 12.3 0.1 0.22 10.7 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase G-patch PF01585.23 OAP62712.1 - 3.4e-08 33.3 0.0 6.1e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 G-patch domain DUF2685 PF10886.8 OAP62712.1 - 0.27 11.5 1.2 0.5 10.6 0.2 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2685) Sec1 PF00995.23 OAP62713.1 - 3.1e-122 409.7 0.0 3.6e-122 409.5 0.0 1.0 1 0 0 1 1 1 1 Sec1 family SUV3_C PF12513.8 OAP62714.1 - 2.1e-17 62.8 2.4 4.3e-17 61.8 2.4 1.6 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.31 OAP62714.1 - 2.2e-10 40.9 0.0 5.1e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Suv3_C_1 PF18147.1 OAP62714.1 - 0.00051 19.8 0.6 0.00087 19.1 0.6 1.4 1 0 0 1 1 1 1 Suv3 C-terminal domain 1 HA2 PF04408.23 OAP62716.1 - 2.5e-24 85.6 1.8 5.4e-24 84.6 0.1 2.6 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 OAP62716.1 - 3e-20 72.3 0.0 6e-20 71.4 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 OAP62716.1 - 3.4e-13 49.9 0.0 8.4e-13 48.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.23 OAP62716.1 - 1.4e-08 34.9 0.2 3e-08 33.9 0.2 1.5 1 0 0 1 1 1 1 S1 RNA binding domain DEAD PF00270.29 OAP62716.1 - 2.9e-05 23.9 0.1 6.6e-05 22.7 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 OAP62716.1 - 0.00018 21.8 0.0 0.00047 20.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 OAP62716.1 - 0.00047 19.9 0.0 0.0021 17.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 OAP62716.1 - 0.0007 18.7 0.0 0.0018 17.4 0.0 1.7 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.6 OAP62716.1 - 0.013 15.8 0.1 0.034 14.5 0.1 1.7 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 OAP62716.1 - 0.014 14.7 0.0 0.026 13.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_33 PF13671.6 OAP62716.1 - 0.021 15.0 0.0 0.16 12.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain Microtub_bd PF16796.5 OAP62716.1 - 0.058 13.3 0.4 0.98 9.4 0.0 2.6 3 0 0 3 3 3 0 Microtubule binding AAA_16 PF13191.6 OAP62716.1 - 0.058 13.8 0.0 0.22 11.9 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 OAP62716.1 - 4.1 7.9 6.6 2.2 8.8 0.1 3.4 3 1 1 4 4 4 0 ABC transporter Aldo_ket_red PF00248.21 OAP62718.1 - 8.9e-44 149.8 0.0 3.5e-43 147.9 0.0 1.8 1 1 0 1 1 1 1 Aldo/keto reductase family Catalase PF00199.19 OAP62719.1 - 4.1e-173 575.9 0.0 7e-173 575.1 0.0 1.3 2 0 0 2 2 2 1 Catalase Catalase-rel PF06628.12 OAP62719.1 - 1.8e-12 47.3 0.0 3.8e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive RNA_polI_A34 PF08208.11 OAP62720.1 - 0.86 9.7 11.1 1.7 8.7 11.1 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Nop14 PF04147.12 OAP62720.1 - 1.4 7.0 24.2 1.8 6.7 24.2 1.2 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 OAP62720.1 - 1.8 7.8 16.7 2.5 7.4 16.7 1.3 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 OAP62720.1 - 2.6 6.2 15.0 3.3 5.9 15.0 1.2 1 0 0 1 1 1 0 CDC45-like protein PLA2_B PF01735.18 OAP62721.1 - 1.2e-76 258.1 1.2 7.2e-76 255.6 1.2 2.0 1 1 0 1 1 1 1 Lysophospholipase catalytic domain PLAC8 PF04749.17 OAP62722.1 - 2e-17 64.0 8.5 2.9e-17 63.5 8.5 1.2 1 0 0 1 1 1 1 PLAC8 family CYSTM PF12734.7 OAP62722.1 - 0.043 14.1 3.7 0.043 14.1 3.7 6.1 5 2 0 5 5 5 0 Cysteine-rich TM module stress tolerance Ank_4 PF13637.6 OAP62723.1 - 8.5e-13 48.5 0.7 1.4e-05 25.5 0.1 3.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 OAP62723.1 - 1.1e-12 48.4 0.2 1.5e-05 25.5 0.0 3.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Helo_like_N PF17111.5 OAP62723.1 - 1.5e-09 37.6 0.3 3.7e-09 36.3 0.0 1.8 2 0 0 2 2 2 1 Fungal N-terminal domain of STAND proteins NACHT PF05729.12 OAP62723.1 - 2.9e-09 37.1 0.1 1e-08 35.3 0.1 2.0 1 0 0 1 1 1 1 NACHT domain Ank PF00023.30 OAP62723.1 - 2.1e-08 34.3 2.0 0.052 14.0 0.0 4.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 OAP62723.1 - 3.4e-06 27.0 2.4 0.48 11.1 0.0 5.1 6 0 0 6 6 4 2 Ankyrin repeat Ank_5 PF13857.6 OAP62723.1 - 5.6e-05 23.3 0.7 0.01 16.1 0.3 3.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) AAA_16 PF13191.6 OAP62723.1 - 0.00023 21.6 1.4 0.00087 19.7 0.1 2.6 3 0 0 3 3 3 1 AAA ATPase domain Lant_dehydr_C PF14028.6 OAP62723.1 - 0.025 14.1 0.3 8.1 5.9 0.0 2.4 2 0 0 2 2 2 0 Lantibiotic biosynthesis dehydratase C-term AAA_22 PF13401.6 OAP62723.1 - 0.1 12.9 0.3 0.48 10.7 0.0 2.2 3 0 0 3 3 3 0 AAA domain DUF848 PF05852.11 OAP62723.1 - 0.53 10.4 3.6 1 9.5 0.1 3.0 4 0 0 4 4 4 0 Gammaherpesvirus protein of unknown function (DUF848) Aa_trans PF01490.18 OAP62724.1 - 4.5e-28 98.1 17.4 8.8e-28 97.1 17.4 1.4 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Glyco_hydro_127 PF07944.12 OAP62724.1 - 8.9e-17 60.8 0.0 6.1e-16 58.0 0.0 1.9 2 0 0 2 2 2 1 Beta-L-arabinofuranosidase, GH127 Peptidase_S26 PF10502.9 OAP62725.1 - 1.3e-07 31.5 0.0 1.8e-06 27.8 0.0 2.4 1 1 0 1 1 1 1 Signal peptidase, peptidase S26 Peptidase_S24 PF00717.23 OAP62725.1 - 0.00029 20.7 0.1 0.00075 19.4 0.1 1.7 2 0 0 2 2 2 1 Peptidase S24-like PBP PF01161.20 OAP62726.1 - 1.1e-08 35.5 0.0 2e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein ArAE_2_N PF10337.9 OAP62727.1 - 1.4e-39 136.5 4.6 2.7e-38 132.2 1.1 2.5 2 0 0 2 2 2 2 Putative ER transporter, 6TM, N-terminal FUSC_2 PF13515.6 OAP62727.1 - 2.8e-15 56.6 14.6 2.8e-15 56.6 14.6 3.7 2 1 2 4 4 4 1 Fusaric acid resistance protein-like ArAE_2 PF10334.9 OAP62727.1 - 5.5e-11 42.7 0.6 9.8e-11 41.9 0.2 1.7 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 ICMT PF04140.14 OAP62727.1 - 0.089 13.2 1.0 22 5.6 0.2 3.0 2 0 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family DUF5336 PF17270.2 OAP62727.1 - 2.6 7.6 10.6 0.87 9.2 1.8 3.4 3 0 0 3 3 3 0 Family of unknown function (DUF5336) Med2 PF11214.8 OAP62728.1 - 2.2e-07 31.0 0.9 4.8e-07 29.9 0.9 1.5 1 0 0 1 1 1 1 Mediator complex subunit 2 SOG2 PF10428.9 OAP62728.1 - 1.9 7.6 13.0 2.6 7.1 13.0 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein DUF4551 PF15087.6 OAP62728.1 - 8.8 5.0 10.6 11 4.7 10.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) RRM_1 PF00076.22 OAP62729.1 - 6.7e-59 195.6 0.0 5.2e-21 74.3 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OAP62729.1 - 1.2e-08 34.5 0.0 0.00043 19.9 0.0 3.3 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OAP62729.1 - 7.5e-08 32.1 0.0 0.0071 16.2 0.0 3.5 3 1 0 3 3 3 2 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 OAP62729.1 - 2.4e-06 27.4 0.1 0.21 11.6 0.0 3.4 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif RRM_8 PF11835.8 OAP62729.1 - 0.00022 21.3 0.0 0.22 11.8 0.0 2.3 2 0 0 2 2 2 2 RRM-like domain RRM_7 PF16367.5 OAP62729.1 - 0.00041 20.4 0.2 1.2 9.4 0.0 3.3 3 1 0 3 3 3 2 RNA recognition motif Cas_Cas2CT1978 PF09707.10 OAP62729.1 - 0.019 15.0 0.0 9.1 6.4 0.0 2.4 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cas2CT1978) ThiP_synth PF10120.9 OAP62730.1 - 0.095 12.3 1.1 0.59 9.7 0.1 2.5 2 1 0 3 3 3 0 Thiamine-phosphate synthase DUF4431 PF14485.6 OAP62730.1 - 0.15 11.9 0.5 0.39 10.5 0.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4431) PKcGMP_CC PF16808.5 OAP62730.1 - 0.68 9.8 0.1 0.68 9.8 0.1 3.4 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase ALIX_LYPXL_bnd PF13949.6 OAP62731.1 - 0.0017 17.7 2.2 0.32 10.2 1.1 2.5 2 0 0 2 2 2 2 ALIX V-shaped domain binding to HIV AAA_16 PF13191.6 OAP62731.1 - 0.0043 17.5 0.8 0.031 14.7 0.1 2.4 2 0 0 2 2 2 1 AAA ATPase domain Rhabdo_ncap PF00945.18 OAP62731.1 - 0.055 12.3 0.0 0.088 11.7 0.0 1.2 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein YabA PF06156.13 OAP62731.1 - 0.17 12.5 5.3 0.12 13.0 3.0 2.0 2 0 0 2 2 2 0 Initiation control protein YabA DUF2951 PF11166.8 OAP62731.1 - 2.8 8.2 7.3 5.6 7.2 4.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) AAA PF00004.29 OAP62732.1 - 3.9e-14 53.2 0.1 1.3e-13 51.5 0.1 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OAP62732.1 - 0.00014 22.3 0.0 0.00036 20.9 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 OAP62732.1 - 0.0002 21.4 0.0 0.0005 20.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 OAP62732.1 - 0.00042 20.6 0.6 0.0041 17.4 0.0 2.4 1 1 1 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.6 OAP62732.1 - 0.0043 17.2 0.4 0.015 15.4 0.0 2.1 2 1 0 2 2 1 1 Sigma-54 interaction domain AAA_33 PF13671.6 OAP62732.1 - 0.0064 16.6 0.4 0.015 15.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 OAP62732.1 - 0.0079 15.9 0.0 0.017 14.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 OAP62732.1 - 0.011 15.5 0.4 0.027 14.2 0.0 1.9 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_30 PF13604.6 OAP62732.1 - 0.02 14.6 0.3 0.055 13.2 0.3 1.8 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.6 OAP62732.1 - 0.021 14.6 0.7 0.059 13.1 0.1 2.0 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 OAP62732.1 - 0.029 14.1 0.0 0.053 13.3 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Sigma54_activat PF00158.26 OAP62732.1 - 0.035 13.8 0.1 0.081 12.6 0.1 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_14 PF13173.6 OAP62732.1 - 0.04 14.0 0.0 0.14 12.1 0.0 2.1 1 1 1 2 2 2 0 AAA domain Torsin PF06309.11 OAP62732.1 - 0.051 13.7 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Torsin AAA_25 PF13481.6 OAP62732.1 - 0.052 13.1 0.0 0.091 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 OAP62732.1 - 0.079 13.4 0.1 0.25 11.7 0.0 1.9 2 0 0 2 2 1 0 RNA helicase BEN PF10523.9 OAP62732.1 - 0.089 13.0 0.1 0.49 10.6 0.0 2.1 2 0 0 2 2 2 0 BEN domain MeaB PF03308.16 OAP62732.1 - 0.096 11.7 0.1 0.19 10.7 0.1 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 OAP62732.1 - 0.097 13.2 1.7 0.26 11.8 0.1 2.5 2 1 0 2 2 2 0 AAA domain AAA_28 PF13521.6 OAP62732.1 - 0.17 12.1 0.1 0.42 10.9 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.14 OAP62732.1 - 0.18 11.9 1.2 0.64 10.1 0.0 2.3 3 0 0 3 3 3 0 AAA domain (Cdc48 subfamily) NACHT PF05729.12 OAP62733.1 - 1.3e-12 47.9 1.6 1.4e-10 41.4 0.6 3.2 2 1 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 OAP62733.1 - 1.6e-06 28.7 2.8 0.0054 17.1 0.0 3.9 4 1 0 4 4 4 2 AAA ATPase domain AAA_22 PF13401.6 OAP62733.1 - 1.2e-05 25.6 0.1 0.0024 18.2 0.0 3.5 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 OAP62733.1 - 0.0086 16.5 0.0 0.027 14.9 0.0 1.9 1 0 0 1 1 1 1 RNA helicase ABC_tran PF00005.27 OAP62733.1 - 0.009 16.5 0.0 0.032 14.8 0.0 1.9 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 OAP62733.1 - 0.012 15.4 0.0 0.028 14.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.6 OAP62733.1 - 0.019 14.7 0.0 0.044 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 OAP62733.1 - 0.019 15.5 0.0 0.071 13.7 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 OAP62733.1 - 0.023 15.2 0.8 0.11 13.0 0.0 2.2 2 1 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 OAP62733.1 - 0.065 13.1 0.0 0.29 11.1 0.0 2.1 2 0 0 2 2 2 0 NTPase AAA PF00004.29 OAP62733.1 - 0.08 13.4 0.0 8.8 6.8 0.0 2.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 OAP62733.1 - 0.1 12.5 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase ATPase_2 PF01637.18 OAP62733.1 - 0.13 12.2 0.0 0.55 10.1 0.0 2.0 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Ploopntkinase3 PF18751.1 OAP62733.1 - 0.15 12.0 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 CMD PF02627.20 OAP62734.1 - 8.8e-12 44.9 6.3 1.4e-08 34.7 2.7 2.3 2 0 0 2 2 2 2 Carboxymuconolactone decarboxylase family Dioxygenase_C PF00775.21 OAP62735.1 - 1.2e-44 151.9 0.0 1.6e-44 151.5 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 OAP62735.1 - 6.2e-26 90.1 0.0 1e-25 89.4 0.0 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 OAP62735.1 - 0.0011 19.2 0.5 0.07 13.4 0.0 2.7 3 0 0 3 3 3 1 Carboxypeptidase regulatory-like domain Lactonase PF10282.9 OAP62736.1 - 4.4e-18 65.6 0.0 7.2e-18 65.0 0.0 1.3 1 1 0 1 1 1 1 Lactonase, 7-bladed beta-propeller DUF4394 PF14339.6 OAP62736.1 - 0.022 14.1 0.0 0.04 13.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4394) Arylesterase PF01731.20 OAP62736.1 - 0.076 13.2 0.1 0.4 10.9 0.0 2.1 2 0 0 2 2 2 0 Arylesterase Abhydrolase_6 PF12697.7 OAP62737.1 - 7.1e-14 52.9 0.5 7.1e-14 52.9 0.5 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAP62737.1 - 5.7e-08 32.7 0.0 7.1e-07 29.1 0.0 2.5 3 0 0 3 3 3 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAP62737.1 - 0.00078 18.8 0.0 0.019 14.2 0.1 2.3 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Esterase PF00756.20 OAP62737.1 - 0.011 15.3 0.0 0.023 14.3 0.0 1.5 1 0 0 1 1 1 0 Putative esterase PIF1 PF05970.14 OAP62738.1 - 5.7e-62 210.0 1.5 1.2e-46 159.6 0.1 2.1 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 OAP62738.1 - 9.4e-23 80.9 0.0 1.8e-22 80.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OAP62738.1 - 2.6e-11 44.0 0.0 6.4e-11 42.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 OAP62738.1 - 3.2e-06 27.5 0.0 1e-05 25.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 OAP62738.1 - 9.5e-05 22.0 1.2 0.00015 21.4 0.0 1.8 2 0 0 2 2 2 1 P-loop containing dynein motor region UvrD_C_2 PF13538.6 OAP62738.1 - 0.00018 21.3 0.0 0.00043 20.0 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.14 OAP62738.1 - 0.0018 16.3 0.2 0.0047 14.9 0.0 1.7 2 0 0 2 2 2 1 Helicase AAA PF00004.29 OAP62738.1 - 0.002 18.6 0.0 0.0061 17.0 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OAP62738.1 - 0.0024 18.3 0.0 0.0058 17.0 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain PhoH PF02562.16 OAP62738.1 - 0.0025 17.3 0.0 0.0093 15.4 0.0 1.9 1 0 0 1 1 1 1 PhoH-like protein NACHT PF05729.12 OAP62738.1 - 0.0071 16.3 0.1 0.025 14.5 0.0 2.0 2 0 0 2 2 2 1 NACHT domain ABC_tran PF00005.27 OAP62738.1 - 0.011 16.3 0.1 0.037 14.5 0.1 2.1 1 1 0 1 1 1 0 ABC transporter NB-ARC PF00931.22 OAP62738.1 - 0.012 14.8 0.0 0.023 13.9 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.22 OAP62738.1 - 0.019 15.4 0.0 0.06 13.7 0.0 2.0 2 0 0 2 2 1 0 RNA helicase T2SSE PF00437.20 OAP62738.1 - 0.021 13.9 0.0 0.038 13.0 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_14 PF13173.6 OAP62738.1 - 0.021 14.9 0.1 0.17 11.9 0.0 2.5 1 1 1 2 2 2 0 AAA domain DUF2075 PF09848.9 OAP62738.1 - 0.028 13.7 0.1 0.086 12.1 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) UvrD-helicase PF00580.21 OAP62738.1 - 0.033 13.7 0.0 0.061 12.8 0.0 1.4 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain RsgA_GTPase PF03193.16 OAP62738.1 - 0.043 13.7 0.0 0.094 12.6 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 OAP62738.1 - 0.053 13.3 0.1 0.13 12.1 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activat PF00158.26 OAP62738.1 - 0.061 13.0 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ATPase_2 PF01637.18 OAP62738.1 - 0.075 12.9 0.8 0.55 10.1 0.8 2.2 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea TsaE PF02367.17 OAP62738.1 - 0.081 12.9 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE YjeF_N PF03853.15 OAP62739.1 - 2.4e-33 115.4 0.0 3.5e-33 114.9 0.0 1.3 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.10 OAP62739.1 - 8.7e-09 36.2 1.1 1.9e-08 35.1 1.1 1.6 1 0 0 1 1 1 1 FDF domain Amidoligase_2 PF12224.8 OAP62741.1 - 2.1e-10 40.7 0.0 7.7e-08 32.3 0.0 3.0 1 1 0 1 1 1 1 Putative amidoligase enzyme IrmA PF18673.1 OAP62741.1 - 0.048 13.8 0.0 0.1 12.8 0.0 1.4 1 0 0 1 1 1 0 interleukin receptor mimic protein A Pro_isomerase PF00160.21 OAP62742.1 - 3.2e-44 151.0 0.0 7e-44 149.9 0.0 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-NOSIP PF15906.5 OAP62742.1 - 9.1e-06 25.7 0.0 2.2e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein U-box PF04564.15 OAP62742.1 - 1.9e-05 24.8 0.0 6.9e-05 22.9 0.0 2.0 1 1 1 2 2 2 1 U-box domain ATP_transf PF09830.9 OAP62743.1 - 5.5e-15 55.3 0.1 2.4e-14 53.2 0.1 2.0 2 0 0 2 2 2 1 ATP adenylyltransferase HIT PF01230.23 OAP62743.1 - 0.19 12.4 0.1 0.88 10.3 0.1 2.2 1 1 0 1 1 1 0 HIT domain GTP_EFTU PF00009.27 OAP62744.1 - 2.3e-58 196.9 0.1 3.2e-58 196.5 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 OAP62744.1 - 2.1e-23 82.8 0.0 6.1e-23 81.3 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 OAP62744.1 - 2.3e-16 59.9 2.8 6.1e-16 58.6 2.8 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 OAP62744.1 - 3.8e-05 23.7 0.0 7.6e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase cobW PF02492.19 OAP62744.1 - 0.012 15.2 0.2 0.26 10.8 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 OAP62744.1 - 0.058 13.1 0.2 4.5 7.0 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 OAP62744.1 - 0.099 12.5 0.1 0.44 10.4 0.0 1.9 1 1 1 2 2 2 0 RsgA GTPase adh_short PF00106.25 OAP62745.1 - 8.6e-14 51.4 0.2 4.2e-10 39.4 0.3 2.2 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAP62745.1 - 1e-12 48.1 0.0 1.5e-08 34.5 0.0 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Bac_luciferase PF00296.20 OAP62746.1 - 1.2e-58 199.0 0.1 1.6e-58 198.6 0.1 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase NAD_binding_8 PF13450.6 OAP62747.1 - 3e-12 46.6 0.0 1.3e-11 44.6 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAP62747.1 - 8.5e-09 35.0 0.0 4.2e-07 29.5 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAP62747.1 - 1.5e-08 34.2 0.1 2.7e-06 26.8 0.0 2.6 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 OAP62747.1 - 3.8e-07 29.6 0.0 3.2e-05 23.3 0.1 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 OAP62747.1 - 6.2e-07 28.2 0.1 8e-06 24.5 0.0 2.4 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_9 PF13454.6 OAP62747.1 - 8.6e-05 22.6 0.1 0.012 15.6 0.0 3.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.24 OAP62747.1 - 0.00019 21.1 0.1 0.0028 17.3 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase DUF4241 PF14025.6 OAP62747.1 - 0.099 12.9 0.0 0.21 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4241) MFS_1 PF07690.16 OAP62748.1 - 1e-24 87.1 36.2 1e-24 87.1 36.2 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily PGG PF13962.6 OAP62748.1 - 3.3 7.6 13.4 1.9 8.3 0.1 3.4 3 1 0 4 4 4 0 Domain of unknown function PAD_porph PF04371.15 OAP62750.1 - 4.6e-100 335.0 0.0 5.2e-100 334.8 0.0 1.0 1 0 0 1 1 1 1 Porphyromonas-type peptidyl-arginine deiminase Amidinotransf PF02274.17 OAP62750.1 - 0.053 12.6 0.0 0.077 12.1 0.0 1.2 1 0 0 1 1 1 0 Amidinotransferase Amidase PF01425.21 OAP62751.1 - 3.3e-48 164.8 0.0 1.4e-42 146.2 0.0 2.1 2 0 0 2 2 2 2 Amidase TPR_12 PF13424.6 OAP62754.1 - 5.6e-34 116.3 24.7 3.2e-11 43.4 2.1 5.9 3 2 3 6 6 6 5 Tetratricopeptide repeat TPR_10 PF13374.6 OAP62754.1 - 4.3e-31 105.9 17.8 2.7e-06 27.1 0.0 7.3 8 0 0 8 8 6 6 Tetratricopeptide repeat NB-ARC PF00931.22 OAP62754.1 - 3.3e-12 46.1 0.0 1e-11 44.5 0.0 1.7 2 0 0 2 2 2 1 NB-ARC domain TPR_4 PF07721.14 OAP62754.1 - 1.9e-11 43.4 26.3 0.13 13.0 1.7 8.5 9 0 0 9 9 6 5 Tetratricopeptide repeat TPR_2 PF07719.17 OAP62754.1 - 3.2e-11 42.5 11.4 0.0038 17.2 0.1 7.1 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 OAP62754.1 - 2e-10 39.9 14.8 0.2 11.7 0.0 7.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 OAP62754.1 - 2.8e-10 39.6 0.7 0.04 13.7 0.0 6.1 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 OAP62754.1 - 4.1e-10 39.1 5.0 0.65 10.3 0.0 6.2 6 0 0 6 6 5 2 Tetratricopeptide repeat DUF676 PF05057.14 OAP62754.1 - 4.1e-06 26.5 0.0 6e-05 22.7 0.0 2.7 3 0 0 3 3 3 1 Putative serine esterase (DUF676) AAA_22 PF13401.6 OAP62754.1 - 3.2e-05 24.2 0.6 0.0011 19.2 0.0 3.7 4 1 1 5 5 4 1 AAA domain TPR_14 PF13428.6 OAP62754.1 - 4.7e-05 23.9 25.4 0.12 13.2 0.3 8.6 7 2 2 9 9 8 2 Tetratricopeptide repeat ANAPC3 PF12895.7 OAP62754.1 - 7e-05 23.0 5.6 0.098 12.9 0.4 4.3 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 Abhydrolase_6 PF12697.7 OAP62754.1 - 0.00016 22.4 0.6 0.00016 22.4 0.6 2.2 2 1 0 2 2 2 1 Alpha/beta hydrolase family AAA_16 PF13191.6 OAP62754.1 - 0.0002 21.8 3.2 0.0014 19.1 0.0 3.4 4 1 0 4 4 3 1 AAA ATPase domain TPR_20 PF14561.6 OAP62754.1 - 0.0003 21.1 4.3 0.32 11.3 0.1 5.0 4 1 1 5 5 5 1 Tetratricopeptide repeat NACHT PF05729.12 OAP62754.1 - 0.00031 20.7 0.0 0.046 13.6 0.0 2.8 2 0 0 2 2 2 1 NACHT domain TPR_19 PF14559.6 OAP62754.1 - 0.00045 20.7 24.3 0.0083 16.6 2.3 6.2 5 2 4 9 9 8 3 Tetratricopeptide repeat TPR_16 PF13432.6 OAP62754.1 - 0.0005 20.7 20.9 0.0064 17.1 0.1 7.4 6 2 1 8 8 7 1 Tetratricopeptide repeat PGAP1 PF07819.13 OAP62754.1 - 0.0025 17.6 0.0 0.0064 16.2 0.0 1.6 1 0 0 1 1 1 1 PGAP1-like protein AAA_33 PF13671.6 OAP62754.1 - 0.0046 17.1 0.1 0.013 15.6 0.1 1.8 1 0 0 1 1 1 1 AAA domain Cutinase PF01083.22 OAP62754.1 - 0.015 15.2 0.0 0.026 14.5 0.0 1.3 1 0 0 1 1 1 0 Cutinase Zeta_toxin PF06414.12 OAP62754.1 - 0.032 13.5 0.0 0.081 12.2 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin ATPase_2 PF01637.18 OAP62754.1 - 0.038 13.9 0.0 0.085 12.8 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Hydrolase_4 PF12146.8 OAP62754.1 - 0.041 13.1 0.0 0.088 12.1 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 TPR_9 PF13371.6 OAP62754.1 - 0.082 13.1 4.0 0.24 11.6 0.3 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 OAP62754.1 - 0.086 13.3 6.7 33 5.2 0.0 6.0 6 0 0 6 6 5 0 Tetratricopeptide repeat AAA PF00004.29 OAP62754.1 - 0.096 13.1 0.1 12 6.4 0.0 2.7 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) SPO22 PF08631.10 OAP62754.1 - 0.36 10.3 3.2 2.8 7.3 0.1 2.5 1 1 0 2 2 2 0 Meiosis protein SPO22/ZIP4 like TPR_21 PF09976.9 OAP62754.1 - 0.54 9.9 5.5 1.6 8.4 3.5 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat-like domain GFA PF04828.14 OAP62755.1 - 5.2e-13 49.1 3.5 7.9e-06 26.1 0.2 2.3 1 1 1 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme DUF2197 PF09963.9 OAP62755.1 - 0.027 14.7 4.2 0.31 11.3 0.2 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) DUF3736 PF12540.8 OAP62756.1 - 0.17 12.0 0.0 0.18 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3736) Response_reg PF00072.24 OAP62757.1 - 1.3e-24 86.5 0.1 3e-24 85.3 0.1 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 OAP62757.1 - 2.8e-23 82.6 0.0 6.9e-23 81.3 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 OAP62757.1 - 4.2e-15 55.5 0.0 1.3e-14 54.0 0.0 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 OAP62757.1 - 0.04 14.3 0.3 0.16 12.4 0.1 2.1 2 0 0 2 2 2 0 HAMP domain COMPASS-Shg1 PF05205.12 OAP62758.1 - 5.9e-27 94.4 1.6 2.6e-26 92.3 0.1 2.8 2 0 0 2 2 2 1 COMPASS (Complex proteins associated with Set1p) component shg1 IF4E PF01652.18 OAP62759.1 - 1.3e-21 77.1 0.1 1.6e-21 76.7 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E HNH_2 PF13391.6 OAP62760.1 - 0.0019 18.3 0.1 0.0066 16.6 0.0 1.9 2 0 0 2 2 2 1 HNH endonuclease Catalase PF00199.19 OAP62761.1 - 2.4e-151 504.2 0.0 2.9e-151 503.9 0.0 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 OAP62761.1 - 6.9e-16 58.2 0.0 1.8e-15 56.9 0.0 1.7 2 0 0 2 2 2 1 Catalase-related immune-responsive NmrA PF05368.13 OAP62762.1 - 1.6e-06 27.9 0.0 3e-06 27.0 0.0 1.5 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAP62762.1 - 3.8e-05 23.7 0.0 6.4e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAP62762.1 - 0.0063 16.0 0.0 0.025 14.1 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Ribonucleas_3_3 PF14622.6 OAP62763.1 - 1e-07 32.2 0.0 1.4e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 OAP62763.1 - 3.3e-06 27.7 0.0 5.7e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease III domain B PF02216.16 OAP62764.1 - 0.11 12.5 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 B domain DUF4543 PF15076.6 OAP62764.1 - 0.12 12.5 0.2 11 6.3 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4543) AAA PF00004.29 OAP62765.1 - 5.4e-43 146.6 1.0 2.5e-15 57.1 0.0 5.7 6 0 0 6 6 4 4 ATPase family associated with various cellular activities (AAA) AAA_12 PF13087.6 OAP62765.1 - 3e-35 121.7 0.0 7.8e-35 120.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 OAP62765.1 - 1.6e-22 80.6 33.2 6.2e-20 72.1 0.0 6.5 6 0 0 6 6 6 2 AAA domain AAA_19 PF13245.6 OAP62765.1 - 3.8e-20 72.7 0.7 1.9e-08 34.7 0.0 5.2 4 2 0 4 4 4 4 AAA domain AAA_lid_6 PF17866.1 OAP62765.1 - 1.2e-18 67.0 0.0 8.8e-09 35.4 0.0 3.9 3 0 0 3 3 3 2 AAA lid domain AAA_30 PF13604.6 OAP62765.1 - 1.3e-17 64.2 4.6 0.0057 16.4 0.0 5.8 5 0 0 5 5 5 5 AAA domain AAA_22 PF13401.6 OAP62765.1 - 3e-15 56.7 1.3 0.0002 21.7 0.0 6.8 4 2 1 5 5 5 3 AAA domain AAA_5 PF07728.14 OAP62765.1 - 9.2e-15 54.8 1.3 0.025 14.6 0.0 5.0 5 0 0 5 5 4 4 AAA domain (dynein-related subfamily) Viral_helicase1 PF01443.18 OAP62765.1 - 6.4e-12 45.7 0.3 0.038 13.7 0.0 5.7 6 0 0 6 6 6 3 Viral (Superfamily 1) RNA helicase Mg_chelatase PF01078.21 OAP62765.1 - 4.4e-09 36.0 0.2 0.33 10.3 0.0 4.8 4 0 0 4 4 4 3 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 OAP62765.1 - 7.4e-09 36.0 0.4 0.44 11.0 0.0 4.6 4 0 0 4 4 4 2 RNA helicase RuvB_N PF05496.12 OAP62765.1 - 9.2e-09 35.2 0.0 0.073 12.8 0.0 4.9 4 0 0 4 4 4 1 Holliday junction DNA helicase RuvB P-loop domain ResIII PF04851.15 OAP62765.1 - 5.2e-08 33.1 0.3 0.0055 16.7 0.0 5.7 6 0 0 6 6 6 1 Type III restriction enzyme, res subunit AAA_33 PF13671.6 OAP62765.1 - 7.8e-08 32.6 9.3 0.094 12.9 0.0 5.8 5 0 0 5 5 5 2 AAA domain IstB_IS21 PF01695.17 OAP62765.1 - 7.5e-06 25.8 0.2 4.2 7.1 0.0 4.5 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_24 PF13479.6 OAP62765.1 - 1.2e-05 25.1 3.2 1.7 8.3 0.1 4.7 4 0 0 4 4 4 1 AAA domain AAA_16 PF13191.6 OAP62765.1 - 1.8e-05 25.2 15.6 0.85 10.0 0.0 5.7 6 0 0 6 6 4 2 AAA ATPase domain Torsin PF06309.11 OAP62765.1 - 2.6e-05 24.3 0.2 9.2 6.4 0.0 4.4 4 0 0 4 4 4 0 Torsin AAA_18 PF13238.6 OAP62765.1 - 4.2e-05 24.1 12.9 0.18 12.3 0.0 5.5 5 0 0 5 5 4 1 AAA domain ATPase PF06745.13 OAP62765.1 - 5.5e-05 22.6 1.1 1.1 8.5 0.0 4.3 4 0 0 4 4 4 1 KaiC TniB PF05621.11 OAP62765.1 - 0.0001 21.7 0.0 3 7.2 0.0 4.8 4 1 0 4 4 4 1 Bacterial TniB protein PhoH PF02562.16 OAP62765.1 - 0.00013 21.5 3.5 1.4 8.3 0.0 4.7 5 0 0 5 5 5 1 PhoH-like protein AAA_14 PF13173.6 OAP62765.1 - 0.00016 21.7 0.0 4.7 7.3 0.0 4.6 4 0 0 4 4 4 1 AAA domain AAA_7 PF12775.7 OAP62765.1 - 0.00043 19.8 1.0 14 5.1 0.2 4.4 4 0 0 4 4 4 0 P-loop containing dynein motor region Sigma54_activat PF00158.26 OAP62765.1 - 0.0014 18.4 1.2 7.7 6.2 0.1 4.6 5 0 0 5 5 5 0 Sigma-54 interaction domain AAA_17 PF13207.6 OAP62765.1 - 0.0016 18.8 12.1 0.024 15.0 0.0 5.6 5 0 0 5 5 5 1 AAA domain DUF2075 PF09848.9 OAP62765.1 - 0.0016 17.7 12.8 0.073 12.3 0.0 6.0 6 1 1 7 7 6 1 Uncharacterized conserved protein (DUF2075) NACHT PF05729.12 OAP62765.1 - 0.015 15.2 1.5 17 5.3 0.0 4.3 4 0 0 4 4 4 0 NACHT domain NTPase_1 PF03266.15 OAP62765.1 - 0.019 14.9 5.0 3.2 7.6 0.0 4.1 4 0 0 4 4 4 0 NTPase AAA_25 PF13481.6 OAP62765.1 - 0.024 14.2 10.5 4.3 6.8 0.1 5.3 5 0 0 5 5 5 0 AAA domain Rad17 PF03215.15 OAP62765.1 - 0.035 14.0 0.2 43 3.9 0.0 4.3 4 0 0 4 4 4 0 Rad17 P-loop domain TsaE PF02367.17 OAP62765.1 - 0.047 13.7 1.5 11 6.0 0.0 3.7 4 0 0 4 4 4 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 OAP62765.1 - 0.062 13.5 13.9 0.37 11.0 0.0 5.0 5 0 0 5 5 4 0 AAA domain 6PF2K PF01591.18 OAP62765.1 - 0.084 12.2 0.5 0.47 9.7 0.1 2.4 3 0 0 3 3 2 0 6-phosphofructo-2-kinase SRP54 PF00448.22 OAP62765.1 - 0.087 12.4 2.4 11 5.5 0.0 3.4 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain Helicase_RecD PF05127.14 OAP62765.1 - 0.12 12.2 0.4 1.2 9.0 0.0 3.0 3 0 0 3 3 2 0 Helicase ADK PF00406.22 OAP62765.1 - 4.6 7.3 6.4 19 5.3 0.0 4.2 4 0 0 4 4 4 0 Adenylate kinase Piwi PF02171.17 OAP62766.1 - 2.5e-73 247.0 0.0 3.6e-73 246.4 0.0 1.2 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 OAP62766.1 - 7.8e-17 62.2 0.0 1.4e-16 61.4 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of argonaute PAZ PF02170.22 OAP62766.1 - 1.5e-10 41.1 0.0 3.2e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 PAZ domain ArgoL1 PF08699.10 OAP62766.1 - 9.2e-10 38.1 0.1 2.8e-09 36.5 0.1 1.9 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoL2 PF16488.5 OAP62766.1 - 2.3e-07 31.1 0.0 7e-07 29.5 0.0 1.9 2 0 0 2 2 2 1 Argonaute linker 2 domain ArgoMid PF16487.5 OAP62766.1 - 0.07 13.4 0.0 0.16 12.3 0.0 1.6 1 0 0 1 1 1 0 Mid domain of argonaute Ribonuclease_3 PF00636.26 OAP62767.1 - 1.5e-42 144.5 0.0 5.1e-22 78.5 0.0 2.8 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 OAP62767.1 - 2.6e-31 108.4 0.0 3.5e-16 59.5 0.0 3.7 2 1 0 2 2 2 2 Ribonuclease-III-like Dicer_dimer PF03368.14 OAP62767.1 - 5e-24 84.3 0.7 7.2e-23 80.6 0.0 2.9 3 0 0 3 3 3 1 Dicer dimerisation domain Helicase_C PF00271.31 OAP62767.1 - 5.8e-19 68.5 0.5 1.7e-18 67.0 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 OAP62767.1 - 6.3e-08 32.6 0.0 1.5e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 OAP62767.1 - 0.00029 20.9 0.0 0.00058 19.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit IBR PF01485.21 OAP62769.1 - 6e-05 23.2 7.9 0.0021 18.3 1.0 2.4 2 0 0 2 2 2 2 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 OAP62769.1 - 0.002 18.0 2.2 0.002 18.0 2.2 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OAP62769.1 - 0.0095 16.2 1.1 0.031 14.6 0.4 2.1 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 OAP62769.1 - 0.022 14.8 5.1 0.052 13.6 5.1 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OAP62769.1 - 0.031 14.1 2.4 0.031 14.1 2.4 2.4 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) CCDC50_N PF15295.6 OAP62769.1 - 0.1 12.8 1.0 8 6.6 0.1 2.4 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 50 N-terminus zf-RING_2 PF13639.6 OAP62769.1 - 0.29 11.5 12.6 0.047 14.0 5.9 2.4 2 0 0 2 2 2 0 Ring finger domain zf-RING_5 PF14634.6 OAP62769.1 - 0.47 10.4 12.6 0.042 13.8 6.1 2.2 2 0 0 2 2 2 0 zinc-RING finger domain Prok-RING_4 PF14447.6 OAP62769.1 - 0.99 9.3 6.4 1.6 8.7 3.9 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 UPRTase PF14681.6 OAP62770.1 - 1.3e-32 112.9 1.0 2.4e-32 112.1 1.0 1.5 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AAA_17 PF13207.6 OAP62770.1 - 1.2e-18 67.9 0.0 2.8e-18 66.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain HAD PF12710.7 OAP62770.1 - 6.5e-14 52.8 0.1 2.5e-13 50.9 0.1 2.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OAP62770.1 - 3e-05 24.4 0.4 8.4e-05 23.0 0.4 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Pribosyltran PF00156.27 OAP62770.1 - 7.4e-05 22.3 1.1 0.00029 20.4 1.1 2.0 1 1 0 1 1 1 1 Phosphoribosyl transferase domain AAA_33 PF13671.6 OAP62770.1 - 0.0003 21.0 0.2 0.00076 19.7 0.1 1.8 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.6 OAP62770.1 - 0.00032 21.1 0.4 0.007 16.8 0.0 2.8 3 0 0 3 3 3 1 AAA ATPase domain AAA_18 PF13238.6 OAP62770.1 - 0.005 17.4 0.2 0.027 15.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain PRTase_2 PF15609.6 OAP62770.1 - 0.023 14.2 0.6 0.063 12.8 0.6 1.7 1 0 0 1 1 1 0 Phosphoribosyl transferase ABC_tran PF00005.27 OAP62770.1 - 0.023 15.2 0.0 0.05 14.1 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_23 PF13476.6 OAP62770.1 - 0.027 15.0 0.0 0.041 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 OAP62770.1 - 0.034 13.4 0.0 0.057 12.7 0.0 1.4 1 0 0 1 1 1 0 KAP family P-loop domain Peptidase_U4 PF03419.13 OAP62770.1 - 0.096 12.0 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 Sporulation factor SpoIIGA AAA_30 PF13604.6 OAP62770.1 - 0.12 12.1 5.4 0.44 10.3 0.0 3.3 3 1 0 3 3 3 0 AAA domain AAA_21 PF13304.6 OAP62770.1 - 0.15 11.8 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system CYTH PF01928.21 OAP62771.1 - 1e-10 41.8 0.0 1.5e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 CYTH domain Reg_prop PF07494.11 OAP62771.1 - 0.094 13.0 0.1 0.25 11.7 0.1 1.7 1 0 0 1 1 1 0 Two component regulator propeller FAD_binding_3 PF01494.19 OAP62772.1 - 4.4e-23 82.1 0.1 2.6e-22 79.5 0.1 1.8 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 OAP62772.1 - 1.8e-07 31.3 0.3 5.5e-07 29.7 0.2 1.9 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAP62772.1 - 1.5e-06 27.7 0.8 2e-05 24.0 1.0 2.1 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAP62772.1 - 2e-06 27.6 3.9 4.1e-06 26.6 3.0 1.7 1 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OAP62772.1 - 0.00013 21.2 2.9 0.00021 20.5 2.9 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 OAP62772.1 - 0.00041 20.8 0.4 0.0012 19.4 0.4 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAP62772.1 - 0.001 18.4 0.1 0.016 14.4 0.2 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAP62772.1 - 0.0024 16.7 0.1 0.0036 16.1 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein Trp_halogenase PF04820.14 OAP62772.1 - 0.0025 16.7 2.4 0.4 9.5 1.0 2.1 2 0 0 2 2 2 2 Tryptophan halogenase GIDA PF01134.22 OAP62772.1 - 0.0041 16.3 0.2 0.0052 15.9 0.2 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Amino_oxidase PF01593.24 OAP62772.1 - 0.016 14.5 0.0 0.26 10.5 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 OAP62772.1 - 0.018 14.4 0.2 0.027 13.8 0.2 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 OAP62772.1 - 0.03 13.6 2.0 0.097 11.9 1.6 1.8 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 OAP62772.1 - 0.087 12.7 0.9 0.16 11.8 0.9 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 OAP62772.1 - 0.09 13.2 0.4 0.36 11.3 0.4 2.1 1 1 0 1 1 1 0 Putative NAD(P)-binding Thi4 PF01946.17 OAP62772.1 - 0.1 11.9 0.5 0.16 11.2 0.5 1.2 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.6 OAP62772.1 - 0.19 11.7 0.2 5.4 7.0 0.4 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding SE PF08491.10 OAP62772.1 - 0.24 10.4 0.0 1.2 8.2 0.0 1.9 2 0 0 2 2 2 0 Squalene epoxidase DUF4598 PF15370.6 OAP62773.1 - 1.3e-22 80.4 2.8 1.3e-22 80.4 2.8 3.2 2 1 0 2 2 2 1 Domain of unknown function (DUF4598) LpxB PF02684.15 OAP62773.1 - 0.04 12.8 0.1 0.051 12.4 0.1 1.1 1 0 0 1 1 1 0 Lipid-A-disaccharide synthetase TetR_C_25 PF17933.1 OAP62773.1 - 0.054 13.8 0.0 0.094 13.0 0.0 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain DUF3391 PF11871.8 OAP62773.1 - 0.12 12.9 4.1 0.27 11.7 4.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) ECSIT_C PF14784.6 OAP62773.1 - 0.18 12.2 1.2 0.35 11.2 1.2 1.5 1 0 0 1 1 1 0 C-terminal domain of the ECSIT protein DUF4551 PF15087.6 OAP62773.1 - 0.76 8.5 6.7 0.86 8.4 6.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DUF2796 PF10986.8 OAP62773.1 - 3.7 7.5 9.2 0.69 9.9 5.7 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2796) Pkinase PF00069.25 OAP62774.1 - 5.2e-17 62.1 0.0 1.2e-16 60.9 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP62774.1 - 9.4e-15 54.6 0.0 3.9e-14 52.6 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinesin PF00225.23 OAP62775.1 - 4.3e-114 380.9 0.0 7.4e-114 380.1 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 OAP62775.1 - 4e-26 91.7 0.7 2.6e-25 89.1 0.0 2.2 2 0 0 2 2 2 1 Microtubule binding DUF3138 PF11336.8 OAP62775.1 - 0.0061 15.2 1.8 0.011 14.4 1.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3138) DUF87 PF01935.17 OAP62775.1 - 0.1 12.6 8.4 0.67 10.0 0.0 2.9 3 0 0 3 3 3 0 Helicase HerA, central domain FAM76 PF16046.5 OAP62775.1 - 0.58 9.5 7.1 0.14 11.5 3.8 1.6 2 0 0 2 2 2 0 FAM76 protein LNP1 PF15419.6 OAP62775.1 - 1.4 9.2 6.0 1.5 9.1 1.9 2.3 2 0 0 2 2 2 0 Leukemia NUP98 fusion partner 1 DUF3037 PF11236.8 OAP62775.1 - 1.5 9.3 5.7 1.3 9.5 3.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3037) Phage_GPO PF05929.11 OAP62775.1 - 1.7 8.2 10.2 0.62 9.6 6.4 2.0 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase HAUS6_N PF14661.6 OAP62775.1 - 3.7 7.1 7.6 1.7 8.2 5.2 1.7 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus HAD PF12710.7 OAP62776.1 - 6.7e-05 23.4 1.9 0.0098 16.3 0.3 2.7 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase DUF1593 PF07632.11 OAP62777.1 - 8.6e-93 310.5 0.0 1.2e-92 310.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1593) REJ PF02010.15 OAP62777.1 - 9.2e-07 28.0 0.0 1.4e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 REJ domain Sugar_tr PF00083.24 OAP62778.1 - 4.8e-64 216.9 21.9 5.6e-64 216.7 21.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP62778.1 - 2.3e-16 59.7 28.6 3.1e-15 55.9 28.3 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 OAP62778.1 - 0.00077 18.4 12.1 0.0013 17.6 0.2 2.6 2 2 0 2 2 2 2 MFS_1 like family Gemini_C4 PF01492.17 OAP62778.1 - 0.17 11.8 0.0 0.36 10.8 0.0 1.5 1 0 0 1 1 1 0 Geminivirus C4 protein ADH_N PF08240.12 OAP62779.1 - 9e-28 96.3 3.0 1.6e-27 95.6 3.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAP62779.1 - 1.8e-12 47.3 0.0 3.4e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 OAP62779.1 - 8.9e-10 38.4 0.5 0.00016 21.3 0.0 2.4 1 1 0 2 2 2 2 Glucose dehydrogenase C-terminus Aldo_ket_red PF00248.21 OAP62780.1 - 2.6e-43 148.3 0.1 3.9e-43 147.7 0.1 1.2 1 1 0 1 1 1 1 Aldo/keto reductase family Transketolase_N PF00456.21 OAP62781.1 - 2.7e-124 414.5 0.0 3.6e-124 414.1 0.0 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 OAP62781.1 - 7e-41 139.9 0.1 1.5e-40 138.8 0.1 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain DXP_synthase_N PF13292.6 OAP62781.1 - 3.3e-06 26.5 0.0 6.3e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Transketolase_C PF02780.20 OAP62781.1 - 1.6e-05 24.8 0.0 3.9e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain TPP_enzyme_C PF02775.21 OAP62781.1 - 0.00058 19.7 0.4 0.005 16.6 0.4 2.5 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain PepSY_2 PF13670.6 OAP62781.1 - 0.024 14.6 0.0 0.072 13.1 0.0 1.8 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain E1_dh PF00676.20 OAP62781.1 - 0.049 12.6 0.0 0.091 11.7 0.0 1.4 1 0 0 1 1 1 0 Dehydrogenase E1 component PAAR_motif PF05488.13 OAP62781.1 - 0.15 12.3 1.2 8.9 6.6 0.0 2.6 2 0 0 2 2 2 0 PAAR motif Peptidase_S41 PF03572.18 OAP62782.1 - 6.3e-12 45.4 0.0 1.3e-11 44.4 0.0 1.5 1 1 0 1 1 1 1 Peptidase family S41 Fungal_trans PF04082.18 OAP62784.1 - 5e-22 78.2 0.0 7.7e-22 77.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP62784.1 - 4.9e-08 33.0 12.3 1.3e-07 31.7 12.3 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAP62785.1 - 1.9e-10 40.2 0.6 3e-10 39.6 0.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain IF-2B PF01008.17 OAP62786.1 - 2e-68 230.7 0.0 2.8e-68 230.2 0.0 1.2 1 0 0 1 1 1 1 Initiation factor 2 subunit family Ribosomal_S14 PF00253.21 OAP62787.1 - 2.8e-13 49.4 2.7 3.9e-13 48.9 2.7 1.2 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e DUF4428 PF14471.6 OAP62787.1 - 0.028 14.3 0.4 0.039 13.9 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) Epimerase PF01370.21 OAP62788.1 - 2.1e-25 89.6 0.0 1.2e-24 87.1 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAP62788.1 - 7.4e-18 65.0 0.0 2.7e-17 63.2 0.0 1.8 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 OAP62788.1 - 1.7e-16 60.0 0.2 1.7e-15 56.8 0.2 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 OAP62788.1 - 4.6e-10 39.7 0.0 9.9e-10 38.6 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 OAP62788.1 - 1.5e-08 34.1 0.0 1.5e-05 24.3 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 OAP62788.1 - 8e-08 31.7 0.0 1.2e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 OAP62788.1 - 2.1e-05 23.8 0.0 0.00018 20.7 0.2 2.3 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.25 OAP62788.1 - 0.0027 17.2 0.0 0.0055 16.2 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAP62788.1 - 0.0035 17.3 0.1 0.025 14.5 0.1 2.1 1 1 0 1 1 1 1 KR domain NmrA PF05368.13 OAP62788.1 - 0.12 11.9 0.2 0.31 10.5 0.2 1.8 1 1 0 1 1 1 0 NmrA-like family Apc13p PF05839.11 OAP62790.1 - 1e-16 60.9 0.0 1.6e-12 47.4 0.0 2.6 2 0 0 2 2 2 2 Apc13p protein Pol_alpha_B_N PF08418.10 OAP62791.1 - 1.2e-75 254.7 0.0 1.7e-75 254.2 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.16 OAP62791.1 - 7.6e-33 113.6 0.0 1.3e-32 112.9 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B CBS PF00571.28 OAP62792.1 - 1.4e-20 73.4 5.8 1.4e-08 35.1 0.0 4.3 4 0 0 4 4 4 3 CBS domain PrpR_N PF06506.11 OAP62792.1 - 0.072 12.7 0.0 0.2 11.2 0.0 1.7 1 1 1 2 2 2 0 Propionate catabolism activator CRAL_TRIO PF00650.20 OAP62793.1 - 1.4e-37 128.8 0.0 2e-37 128.3 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 OAP62793.1 - 5.6e-14 52.1 0.0 1.2e-13 51.0 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 OAP62793.1 - 0.067 13.3 0.0 0.099 12.8 0.0 1.2 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain Lipocalin_5 PF13924.6 OAP62794.1 - 6.7e-28 97.3 0.0 7.9e-28 97.0 0.0 1.1 1 0 0 1 1 1 1 Lipocalin-like domain DUF4850 PF16142.5 OAP62794.1 - 0.04 13.4 0.0 0.061 12.8 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4850) MFAP1 PF06991.11 OAP62795.1 - 8.3e-63 212.1 22.8 8.3e-63 212.1 22.8 2.7 1 1 1 2 2 2 1 Microfibril-associated/Pre-mRNA processing SARAF PF06682.12 OAP62795.1 - 2.4 7.7 12.6 5.5 6.5 12.6 1.6 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis TRAPP PF04051.16 OAP62796.1 - 6.4e-38 129.7 0.0 1e-37 129.1 0.0 1.3 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component NAD_kinase PF01513.21 OAP62797.1 - 2.2e-72 243.7 0.0 3.7e-72 243.0 0.0 1.3 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 OAP62797.1 - 0.011 15.3 0.0 0.09 12.4 0.0 2.4 2 1 1 3 3 3 0 Diacylglycerol kinase catalytic domain SWIRM-assoc_1 PF16495.5 OAP62797.1 - 0.049 13.6 5.1 0.095 12.7 5.1 1.4 1 0 0 1 1 1 0 SWIRM-associated region 1 UCH PF00443.29 OAP62798.1 - 1.3e-38 132.9 0.0 1.9e-38 132.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OAP62798.1 - 1.9e-06 27.7 0.1 2.7e-05 23.9 0.1 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase SEN1_N PF12726.7 OAP62798.1 - 0.099 10.9 0.1 0.14 10.4 0.1 1.1 1 0 0 1 1 1 0 SEN1 N terminal Las1 PF04031.13 OAP62799.1 - 6.9e-38 130.2 3.3 2.6e-18 66.6 0.1 2.1 2 0 0 2 2 2 2 Las1-like HCMVantigenic_N PF12154.8 OAP62800.1 - 0.52 10.5 8.8 3.2 8.0 5.5 2.6 2 0 0 2 2 2 0 Glycoprotein B N-terminal antigenic domain of HCMV CDC45 PF02724.14 OAP62800.1 - 0.63 8.3 4.4 0.81 7.9 4.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 OAP62800.1 - 4.4 5.4 8.5 5.5 5.1 8.5 1.1 1 0 0 1 1 1 0 Nop14-like family PAT1 PF09770.9 OAP62801.1 - 0 1137.6 6.5 0 1134.2 6.5 1.9 1 1 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Glyco_transf_15 PF01793.16 OAP62802.1 - 3.7e-135 450.3 3.0 4.6e-135 450.0 3.0 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Ribosom_S12_S23 PF00164.25 OAP62803.1 - 5.2e-28 96.9 0.8 7.9e-28 96.4 0.8 1.3 1 0 0 1 1 1 1 Ribosomal protein S12/S23 SPATIAL PF15256.6 OAP62803.1 - 0.02 15.3 0.1 0.026 14.9 0.1 1.2 1 0 0 1 1 1 0 SPATIAL Acetyltransf_1 PF00583.25 OAP62804.1 - 8e-10 39.0 0.0 1.2e-09 38.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OAP62804.1 - 2.2e-08 34.1 0.0 3.3e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OAP62804.1 - 4.5e-07 30.2 0.0 7.3e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAP62804.1 - 4.1e-05 23.5 0.0 7.2e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_13 PF13880.6 OAP62804.1 - 0.0029 17.5 0.0 0.0059 16.6 0.0 1.5 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase Acetyltransf_9 PF13527.7 OAP62804.1 - 0.004 17.2 0.0 0.0096 16.0 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PanZ PF12568.8 OAP62804.1 - 0.12 12.1 0.1 0.24 11.1 0.1 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_CG PF14542.6 OAP62804.1 - 0.18 12.0 0.0 0.31 11.2 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase adh_short_C2 PF13561.6 OAP62805.1 - 1.8e-60 204.4 0.0 2.2e-60 204.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP62805.1 - 1e-50 171.9 0.4 1.3e-50 171.6 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAP62805.1 - 6e-13 49.1 0.1 8.1e-13 48.7 0.1 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 OAP62805.1 - 6.3e-05 22.5 0.0 9.7e-05 21.9 0.0 1.4 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 OAP62805.1 - 0.026 14.0 0.1 0.042 13.3 0.1 1.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Glyco_trans_4_4 PF13579.6 OAP62805.1 - 0.045 14.2 0.2 0.26 11.7 0.0 1.9 2 0 0 2 2 2 0 Glycosyl transferase 4-like domain baeRF_family10 PF18854.1 OAP62805.1 - 0.17 12.1 0.1 0.27 11.5 0.1 1.2 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 10 zf-C2HE PF16278.5 OAP62808.1 - 5.2e-19 68.5 1.2 1.2e-18 67.3 1.2 1.7 1 0 0 1 1 1 1 C2HE / C2H2 / C2HC zinc-binding finger DcpS_C PF11969.8 OAP62808.1 - 1.4e-15 57.8 4.9 9.7e-15 55.0 4.9 2.0 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 OAP62808.1 - 7.3e-15 55.5 0.2 1.9e-14 54.2 0.2 1.7 1 1 0 1 1 1 1 HIT domain Ras PF00071.22 OAP62809.1 - 2.6e-60 202.7 0.1 3.1e-60 202.5 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAP62809.1 - 1.9e-20 73.3 0.0 2.9e-20 72.7 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAP62809.1 - 6.8e-08 32.2 0.0 7.6e-08 32.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OAP62809.1 - 4.1e-06 26.5 0.1 3.9e-05 23.3 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OAP62809.1 - 5.8e-05 23.1 0.6 0.24 11.3 0.0 2.4 1 1 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OAP62809.1 - 0.0023 18.0 0.0 0.0035 17.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 OAP62809.1 - 0.004 17.2 0.0 0.0073 16.3 0.0 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain FeoB_N PF02421.18 OAP62809.1 - 0.0054 16.3 0.0 0.0086 15.6 0.0 1.3 1 1 0 1 1 1 1 Ferrous iron transport protein B DUF2075 PF09848.9 OAP62809.1 - 0.053 12.8 0.3 7.2 5.7 0.1 2.0 1 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) IstB_IS21 PF01695.17 OAP62809.1 - 0.11 12.2 0.5 1.6 8.5 0.1 2.2 1 1 1 2 2 2 0 IstB-like ATP binding protein Ser_hydrolase PF06821.13 OAP62809.1 - 0.16 11.8 0.0 0.22 11.3 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase MoCF_biosynth PF00994.24 OAP62810.1 - 7.3e-33 113.2 0.0 5e-32 110.5 0.0 2.0 2 0 0 2 2 2 1 Probable molybdopterin binding domain Cofilin_ADF PF00241.20 OAP62811.1 - 8.4e-18 64.3 0.0 1e-17 64.1 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein FAD_binding_3 PF01494.19 OAP62812.1 - 5.5e-72 242.9 0.0 6.8e-72 242.6 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 OAP62812.1 - 9e-37 126.7 0.0 1.4e-36 126.0 0.0 1.3 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox_2 PF07992.14 OAP62812.1 - 1.9e-05 24.1 0.0 0.014 14.7 0.0 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAP62812.1 - 0.00056 19.6 0.2 0.033 13.8 0.1 2.2 1 1 1 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAP62812.1 - 0.0094 16.2 0.0 0.032 14.5 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 OAP62812.1 - 0.013 16.0 0.0 0.14 12.7 0.0 2.5 2 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAP62812.1 - 0.027 13.2 0.0 0.059 12.1 0.0 1.5 1 0 0 1 1 1 0 HI0933-like protein Lycopene_cycl PF05834.12 OAP62812.1 - 0.044 12.8 0.0 0.099 11.7 0.0 1.5 2 0 0 2 2 2 0 Lycopene cyclase protein ApbA PF02558.16 OAP62812.1 - 0.047 13.3 0.1 0.13 11.9 0.0 1.7 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.14 OAP62812.1 - 0.15 11.6 0.0 0.42 10.2 0.0 1.7 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Asparaginase_II PF06089.12 OAP62812.1 - 0.19 10.7 0.0 0.3 10.0 0.0 1.2 1 0 0 1 1 1 0 L-asparaginase II Nup192 PF11894.8 OAP62814.1 - 0 1075.2 0.2 0 1075.0 0.2 1.0 1 0 0 1 1 1 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 PI3_PI4_kinase PF00454.27 OAP62815.1 - 7.7e-50 170.0 0.0 1.7e-49 168.9 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.8 OAP62815.1 - 3.4e-34 118.1 0.1 3.4e-34 118.1 0.1 2.6 2 0 0 2 2 2 1 Telomere-length maintenance and DNA damage repair FATC PF02260.20 OAP62815.1 - 2.1e-12 46.6 0.0 9.2e-12 44.6 0.0 2.1 2 0 0 2 2 2 1 FATC domain DNApol_Exo PF18136.1 OAP62816.1 - 1.8e-105 352.1 0.0 3.1e-105 351.4 0.0 1.4 1 0 0 1 1 1 1 DNA mitochondrial polymerase exonuclease domain DNA_pol_A PF00476.20 OAP62816.1 - 1.7e-57 195.2 0.0 2.8e-57 194.5 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family A DNA_pol_A_exo1 PF01612.20 OAP62816.1 - 0.027 14.2 0.1 0.19 11.4 0.1 2.3 1 1 0 1 1 1 0 3'-5' exonuclease DUF4604 PF15377.6 OAP62817.1 - 7.5e-27 94.8 15.5 8.4e-27 94.7 15.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) Adaptin_binding PF10199.9 OAP62818.1 - 1.2e-12 48.5 6.2 1.1e-11 45.3 4.0 2.5 2 1 0 2 2 2 1 Alpha and gamma adaptin binding protein p34 LSM PF01423.22 OAP62819.1 - 2.1e-15 56.2 0.1 3e-15 55.6 0.1 1.3 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 OAP62819.1 - 0.15 12.2 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 Ataxin 2 SM domain PGP_phosphatase PF09419.10 OAP62820.1 - 1.2e-52 177.9 0.0 1.5e-52 177.6 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.6 OAP62820.1 - 9.2e-07 28.8 0.0 1.7e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 OAP62820.1 - 0.032 14.5 0.0 3.1 8.0 0.0 2.1 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase Turandot PF07240.11 OAP62822.1 - 0.053 13.5 0.0 0.08 12.9 0.0 1.3 1 0 0 1 1 1 0 Stress-inducible humoral factor Turandot Cullin_binding PF03556.15 OAP62824.1 - 2.6e-31 108.6 0.3 3.7e-31 108.1 0.3 1.2 1 0 0 1 1 1 1 Cullin binding vWA-TerF-like PF10138.9 OAP62825.1 - 8.1e-07 29.3 0.0 1.2e-06 28.8 0.0 1.2 1 0 0 1 1 1 1 vWA found in TerF C terminus DnaG_DnaB_bind PF08278.11 OAP62825.1 - 0.067 13.8 0.0 4.7 7.8 0.0 2.8 2 1 0 2 2 2 0 DNA primase DnaG DnaB-binding Sugar_tr PF00083.24 OAP62827.1 - 2.1e-86 290.6 19.8 2.4e-86 290.4 19.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP62827.1 - 2.2e-25 89.4 36.6 8.1e-25 87.5 15.4 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 OAP62827.1 - 2.5e-06 26.2 6.2 4.2e-05 22.2 0.9 2.2 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) SpoVAB PF13782.6 OAP62827.1 - 0.017 15.4 0.3 2 8.7 0.1 2.8 2 0 0 2 2 2 0 Stage V sporulation protein AB S_locus_glycop PF00954.20 OAP62828.1 - 0.034 14.7 3.5 0.034 14.7 3.5 2.5 2 0 0 2 2 2 0 S-locus glycoprotein domain RIFIN PF02009.16 OAP62828.1 - 4.6 7.0 6.0 6.1 6.6 6.0 1.1 1 0 0 1 1 1 0 Rifin RL10P_insert PF17777.1 OAP62829.1 - 3.2e-26 91.1 0.0 5.6e-26 90.3 0.0 1.4 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 OAP62829.1 - 1.5e-17 63.5 0.0 2.4e-17 62.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 AA_permease_2 PF13520.6 OAP62830.1 - 1.9e-63 214.8 60.6 1.9e-63 214.8 60.6 1.3 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAP62830.1 - 7.7e-21 74.2 50.2 1e-20 73.8 50.2 1.1 1 0 0 1 1 1 1 Amino acid permease GATA-N PF05349.12 OAP62830.1 - 0.043 14.1 0.2 0.21 11.9 0.0 2.1 2 0 0 2 2 2 0 GATA-type transcription activator, N-terminal Gram_pos_anchor PF00746.21 OAP62830.1 - 0.49 10.4 2.7 34 4.5 0.0 2.9 2 0 0 2 2 2 0 LPXTG cell wall anchor motif PNP_UDP_1 PF01048.20 OAP62831.1 - 1.7e-14 53.7 0.0 3.8e-14 52.5 0.0 1.6 1 0 0 1 1 1 1 Phosphorylase superfamily DUF2967 PF11179.8 OAP62831.1 - 0.86 7.6 12.1 0.5 8.4 9.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2967) MatE PF01554.18 OAP62832.1 - 9.7e-39 132.6 23.8 1.3e-36 125.6 8.2 2.4 2 1 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 OAP62832.1 - 2.3e-05 24.5 7.7 2.3e-05 24.5 7.7 3.2 1 1 2 3 3 3 1 Polysaccharide biosynthesis C-terminal domain PTPLA PF04387.14 OAP62833.1 - 2.9e-54 183.2 5.9 2.9e-54 183.2 5.9 1.5 2 0 0 2 2 2 1 Protein tyrosine phosphatase-like protein, PTPLA GTP_EFTU PF00009.27 OAP62834.1 - 2.7e-58 196.7 0.0 4.2e-58 196.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 OAP62834.1 - 1.1e-14 54.2 0.0 2.7e-14 53.0 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 OAP62834.1 - 3e-08 33.6 0.0 7.1e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 OAP62834.1 - 1e-07 32.2 0.0 3.3e-07 30.6 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_IV PF03764.18 OAP62834.1 - 0.0004 20.2 0.1 0.004 16.9 0.0 2.6 3 0 0 3 3 3 1 Elongation factor G, domain IV MMR_HSR1 PF01926.23 OAP62834.1 - 0.048 13.8 0.0 0.15 12.1 0.0 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase PRP3 PF08572.10 OAP62834.1 - 0.079 12.7 1.3 0.24 11.1 0.0 2.0 2 0 0 2 2 2 0 pre-mRNA processing factor 3 (PRP3) U1snRNP70_N PF12220.8 OAP62834.1 - 0.44 11.2 3.3 9.7 6.9 0.1 3.3 3 0 0 3 3 3 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal FAD_binding_3 PF01494.19 OAP62836.1 - 4.1e-18 65.7 2.1 9.6e-13 48.1 0.3 2.5 2 1 0 2 2 2 2 FAD binding domain Pyr_redox PF00070.27 OAP62836.1 - 0.00017 22.1 0.5 0.21 12.2 0.2 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAP62836.1 - 0.00023 20.9 0.0 0.00036 20.2 0.0 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAP62836.1 - 0.00075 19.7 0.0 0.0017 18.6 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAP62836.1 - 0.00099 18.4 0.0 0.67 9.1 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAP62836.1 - 0.017 14.4 0.3 2 7.6 0.1 2.5 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase 7TMR-DISMED2 PF07696.11 OAP62836.1 - 0.042 13.9 0.1 0.21 11.7 0.1 1.9 2 0 0 2 2 2 0 7TMR-DISM extracellular 2 Lycopene_cycl PF05834.12 OAP62836.1 - 0.05 12.7 0.0 2.5 7.0 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein Methyltransf_23 PF13489.6 OAP62837.1 - 1.3e-27 96.6 0.0 1.9e-27 96.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAP62837.1 - 6.4e-12 46.0 0.0 2.3e-11 44.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAP62837.1 - 2.6e-10 40.8 0.0 5.3e-09 36.6 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAP62837.1 - 4.7e-08 33.0 0.0 0.0066 16.2 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 OAP62837.1 - 6.6e-08 33.2 0.0 5.6e-07 30.2 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAP62837.1 - 0.0035 16.7 0.0 0.37 10.1 0.0 2.8 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.9 OAP62837.1 - 0.0069 16.1 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 OAP62837.1 - 0.014 15.0 0.0 0.024 14.2 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_2 PF00891.18 OAP62837.1 - 0.02 14.2 0.0 0.16 11.3 0.0 2.1 3 0 0 3 3 3 0 O-methyltransferase domain PrmA PF06325.13 OAP62837.1 - 0.073 12.5 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) EXOSC1 PF10447.9 OAP62838.1 - 1.9e-17 63.9 3.1 5.1e-16 59.3 3.1 2.2 1 1 0 1 1 1 1 Exosome component EXOSC1/CSL4 ECR1_N PF14382.6 OAP62838.1 - 3.6e-10 39.5 0.1 8.3e-10 38.3 0.1 1.7 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region Arm PF00514.23 OAP62839.1 - 3.1e-75 246.2 28.5 1.5e-12 47.1 0.1 11.1 11 0 0 11 11 11 9 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 OAP62839.1 - 3.4e-20 72.1 11.2 7.1e-07 29.6 0.1 7.8 5 1 3 8 8 8 5 HEAT-like repeat HEAT_2 PF13646.6 OAP62839.1 - 1.1e-17 64.2 8.5 0.0037 17.6 0.1 7.4 4 2 1 6 6 6 4 HEAT repeats HEAT PF02985.22 OAP62839.1 - 6.2e-15 54.0 14.7 0.18 12.2 0.0 8.7 10 0 0 10 10 8 4 HEAT repeat Arm_2 PF04826.13 OAP62839.1 - 2.1e-11 43.8 3.8 1.4e-05 24.7 0.5 2.9 1 1 0 2 2 2 2 Armadillo-like Adaptin_N PF01602.20 OAP62839.1 - 4.6e-10 38.7 10.8 3.8e-06 25.8 0.2 2.9 2 1 1 3 3 3 2 Adaptin N terminal region KAP PF05804.12 OAP62839.1 - 3.1e-09 35.6 1.5 4.1e-09 35.2 0.1 1.8 2 1 1 3 3 3 1 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.14 OAP62839.1 - 9.2e-08 31.7 1.8 0.00033 20.0 2.0 3.5 2 1 1 3 3 3 2 V-ATPase subunit H Cnd1 PF12717.7 OAP62839.1 - 1.3e-05 25.3 7.3 0.026 14.6 0.2 5.0 1 1 3 6 6 6 2 non-SMC mitotic condensation complex subunit 1 DUF3361 PF11841.8 OAP62839.1 - 2.2e-05 24.4 7.2 0.62 10.0 0.4 4.4 2 1 3 5 5 5 2 Domain of unknown function (DUF3361) V-ATPase_H_C PF11698.8 OAP62839.1 - 0.0015 18.7 4.8 18 5.5 0.1 5.2 2 1 6 8 8 8 0 V-ATPase subunit H HEAT_PBS PF03130.16 OAP62839.1 - 0.0026 18.3 10.1 3.6 8.5 0.8 6.8 7 0 0 7 7 6 1 PBS lyase HEAT-like repeat Atx10homo_assoc PF09759.9 OAP62839.1 - 0.0095 15.9 4.0 3 7.9 0.0 4.7 3 1 2 6 6 6 1 Spinocerebellar ataxia type 10 protein domain UNC45-central PF11701.8 OAP62839.1 - 0.026 14.5 2.4 6.6 6.7 0.1 3.4 3 1 0 3 3 3 0 Myosin-binding striated muscle assembly central Vac14_Fab1_bd PF12755.7 OAP62839.1 - 0.14 12.7 0.1 2 9.1 0.0 3.0 2 1 1 3 3 3 0 Vacuolar 14 Fab1-binding region eRF1_1 PF03463.15 OAP62839.1 - 0.33 10.9 2.4 0.47 10.5 0.4 2.1 2 0 0 2 2 2 0 eRF1 domain 1 Pex19 PF04614.12 OAP62839.1 - 8.5 6.1 7.2 13 5.5 3.7 2.6 2 1 0 2 2 2 0 Pex19 protein family Trypan_PARP PF05887.11 OAP62840.1 - 0.0004 20.4 2.6 0.00083 19.3 2.6 1.5 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) Mucin PF01456.17 OAP62840.1 - 0.098 12.6 14.3 0.083 12.9 13.1 1.5 1 1 0 1 1 1 0 Mucin-like glycoprotein NESP55 PF06390.12 OAP62840.1 - 0.14 11.8 7.4 0.22 11.1 7.4 1.3 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) T6_Ig_like PF18002.1 OAP62840.1 - 3.2 7.6 9.7 6.9 6.5 0.8 2.4 1 1 1 2 2 2 0 T6 antigen Ig like domain U1snRNP70_N PF12220.8 OAP62841.1 - 1.7e-24 86.3 6.6 2.6e-24 85.7 6.6 1.3 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.22 OAP62841.1 - 2.4e-13 49.7 0.0 4.5e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OAP62841.1 - 9.1e-06 25.7 0.0 1.7e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif FAD_binding_4 PF01565.23 OAP62842.1 - 2e-23 82.6 3.0 4.3e-23 81.6 3.0 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 OAP62842.1 - 3.2e-12 46.4 0.0 7.3e-12 45.2 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like L51_S25_CI-B8 PF05047.16 OAP62843.1 - 4e-08 33.0 0.0 6.2e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain zf-RING_UBOX PF13445.6 OAP62844.1 - 0.00068 19.6 0.2 0.0014 18.6 0.2 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OAP62844.1 - 0.0015 18.4 0.1 0.0026 17.6 0.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAP62844.1 - 0.0032 17.4 0.4 0.0058 16.6 0.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 OAP62844.1 - 0.0072 16.6 0.4 0.015 15.6 0.4 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 OAP62844.1 - 0.034 14.0 1.2 0.077 12.9 1.2 1.5 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OAP62844.1 - 0.054 13.3 3.2 0.38 10.6 3.6 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Lar_restr_allev PF14354.6 OAP62844.1 - 0.08 13.3 0.9 0.2 12.0 0.9 1.7 1 0 0 1 1 1 0 Restriction alleviation protein Lar zf-C3HC4_4 PF15227.6 OAP62844.1 - 0.33 11.2 1.5 0.65 10.2 0.2 2.0 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 OAP62844.1 - 0.46 10.4 3.1 14 5.7 4.0 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Prp19 PF08606.11 OAP62845.1 - 1e-30 105.5 3.8 2.1e-30 104.5 3.8 1.6 1 0 0 1 1 1 1 Prp19/Pso4-like ANAPC4_WD40 PF12894.7 OAP62845.1 - 9.4e-16 57.9 0.0 4.6e-05 23.6 0.0 3.8 1 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OAP62845.1 - 6.5e-13 48.9 5.6 0.00013 22.7 0.0 4.8 5 1 0 5 5 5 3 WD domain, G-beta repeat eIF2A PF08662.11 OAP62845.1 - 3.8e-05 23.6 0.0 0.00096 19.1 0.0 2.6 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 OAP62845.1 - 0.002 17.2 0.0 0.0095 14.9 0.0 2.1 1 1 1 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein V_ATPase_I_N PF18670.1 OAP62845.1 - 0.0034 17.7 0.2 0.0081 16.5 0.2 1.6 1 0 0 1 1 1 1 V-type ATPase subunit I, N-terminal domain DUF3450 PF11932.8 OAP62845.1 - 0.026 13.8 1.2 0.048 13.0 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) zf-Nse PF11789.8 OAP62845.1 - 0.038 13.8 0.0 0.088 12.6 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit PQQ PF01011.21 OAP62845.1 - 0.058 13.4 0.0 0.24 11.4 0.0 2.2 2 0 0 2 2 2 0 PQQ enzyme repeat SnoaL_4 PF13577.6 OAP62845.1 - 0.11 12.7 0.1 0.53 10.4 0.0 2.1 2 0 0 2 2 2 0 SnoaL-like domain Frtz PF11768.8 OAP62845.1 - 0.17 10.1 0.0 0.93 7.7 0.0 2.0 1 1 1 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz Na_H_Exchanger PF00999.21 OAP62846.1 - 3.7e-33 114.9 28.0 4.4e-24 85.0 26.4 2.2 2 0 0 2 2 2 2 Sodium/hydrogen exchanger family DUF2070 PF09843.9 OAP62846.1 - 1.4 7.1 10.5 2.3 6.4 10.5 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) MMR_HSR1 PF01926.23 OAP62848.1 - 7.3e-09 35.7 0.0 1.3e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 OAP62848.1 - 2.6e-05 23.7 0.0 3.7e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 AIG1 family FeoB_N PF02421.18 OAP62848.1 - 0.0037 16.8 0.0 0.0069 15.9 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 OAP62848.1 - 0.01 15.9 0.7 11 6.1 0.1 3.3 3 1 1 4 4 4 0 Dynamin family RsgA_GTPase PF03193.16 OAP62848.1 - 0.017 15.0 0.4 0.052 13.4 0.4 1.8 1 1 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 OAP62848.1 - 0.025 14.9 0.0 0.054 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.14 OAP62848.1 - 0.15 12.0 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Zn_clus PF00172.18 OAP62849.1 - 1.3e-05 25.2 11.2 2.6e-05 24.2 11.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AA_permease_2 PF13520.6 OAP62851.1 - 3e-53 181.2 44.8 4.1e-53 180.7 44.8 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAP62851.1 - 3.6e-19 68.7 41.0 5.3e-19 68.2 41.0 1.1 1 0 0 1 1 1 1 Amino acid permease Acetyltransf_1 PF00583.25 OAP62852.1 - 2.3e-11 43.9 0.0 4.1e-11 43.1 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OAP62852.1 - 6.4e-09 36.1 0.0 1.3e-08 35.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OAP62852.1 - 2e-07 31.0 0.0 3.4e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 OAP62852.1 - 2.7e-07 30.7 0.3 2e-05 24.6 0.0 2.6 2 1 1 3 3 3 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAP62852.1 - 0.0052 16.7 0.0 0.0092 15.9 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 OAP62852.1 - 0.0053 16.8 0.0 0.01 15.9 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase RseC_MucC PF04246.12 OAP62853.1 - 1.9 8.4 5.9 0.86 9.6 1.1 2.4 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC AA_permease_2 PF13520.6 OAP62854.1 - 3.1e-59 200.9 47.3 3.8e-59 200.6 47.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAP62854.1 - 1.9e-29 102.6 37.6 2.5e-29 102.2 37.6 1.1 1 0 0 1 1 1 1 Amino acid permease COX4 PF02936.14 OAP62854.1 - 0.59 10.2 2.5 0.74 9.8 0.2 2.4 2 0 0 2 2 2 0 Cytochrome c oxidase subunit IV NACHT PF05729.12 OAP62855.1 - 4.3e-05 23.5 0.0 9.3e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 OAP62855.1 - 0.0021 18.5 0.1 0.018 15.4 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain DUF2075 PF09848.9 OAP62855.1 - 0.0082 15.4 0.0 0.015 14.5 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 OAP62855.1 - 0.13 12.3 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit NB-ARC PF00931.22 OAP62855.1 - 0.14 11.4 0.0 0.28 10.3 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain Homeodomain PF00046.29 OAP62856.1 - 5.4e-18 64.6 4.8 1.2e-17 63.5 4.8 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 OAP62856.1 - 1.7e-05 24.7 1.5 4.1e-05 23.4 1.5 1.7 1 0 0 1 1 1 1 Homeobox KN domain HTH_23 PF13384.6 OAP62856.1 - 0.26 11.2 0.3 0.49 10.3 0.3 1.4 1 0 0 1 1 1 0 Homeodomain-like domain PhoLip_ATPase_C PF16212.5 OAP62857.1 - 1.3e-69 234.7 21.2 1.3e-69 234.7 21.2 2.3 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 OAP62857.1 - 1e-22 79.5 0.0 3.4e-22 77.9 0.0 1.9 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 OAP62857.1 - 2.9e-15 57.1 0.0 2.6e-05 24.6 0.0 3.4 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 OAP62857.1 - 3e-11 43.2 0.1 1e-10 41.4 0.1 2.0 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase PF13246.6 OAP62857.1 - 1.2e-09 38.1 0.0 8.7e-09 35.4 0.0 2.4 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 OAP62857.1 - 0.00053 19.8 0.1 0.0016 18.2 0.1 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase TPR_15 PF13429.6 OAP62857.1 - 0.0083 15.4 0.9 0.021 14.1 0.9 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat MFS_1 PF07690.16 OAP62858.1 - 1.3e-41 142.8 16.9 1.6e-41 142.4 16.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAP62858.1 - 4.8e-11 42.2 10.3 1.6e-10 40.5 9.5 1.8 1 1 1 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 OAP62858.1 - 1.1e-06 27.4 5.1 1.4e-06 27.0 5.1 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 OAP62858.1 - 0.071 11.5 6.2 0.091 11.1 6.2 1.1 1 0 0 1 1 1 0 Transmembrane secretion effector Transgly_assoc PF04226.13 OAP62858.1 - 1.1 9.6 4.7 3.2 8.1 4.7 1.8 1 0 0 1 1 1 0 Transglycosylase associated protein OATP PF03137.20 OAP62858.1 - 1.6 6.9 8.1 5.7 5.1 7.6 2.4 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.7 OAP62858.1 - 2.6 6.8 8.2 0.64 8.8 2.4 2.4 2 1 1 3 3 3 0 MFS_1 like family RET_CLD1 PF17756.1 OAP62859.1 - 0.17 12.2 0.0 0.26 11.6 0.0 1.2 1 0 0 1 1 1 0 RET Cadherin like domain 1 ANAPC4_WD40 PF12894.7 OAP62860.1 - 1.6e-07 31.5 0.0 0.028 14.7 0.0 3.9 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OAP62860.1 - 0.0031 18.3 6.0 7.3 7.6 0.0 5.2 6 0 0 6 6 6 2 WD domain, G-beta repeat PGAP1 PF07819.13 OAP62861.1 - 1e-07 32.0 0.0 2e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.14 OAP62861.1 - 2.9e-06 27.0 0.0 5.8e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 OAP62861.1 - 5.4e-06 27.2 0.0 1e-05 26.3 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family NACHT PF05729.12 OAP62861.1 - 1.8e-05 24.8 0.0 7e-05 22.8 0.0 2.1 1 1 1 2 2 2 1 NACHT domain LCAT PF02450.15 OAP62861.1 - 0.00011 21.5 0.0 0.0002 20.6 0.0 1.3 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Thioesterase PF00975.20 OAP62861.1 - 0.00094 19.4 0.1 0.0031 17.6 0.0 1.9 2 0 0 2 2 2 1 Thioesterase domain Abhydrolase_1 PF00561.20 OAP62861.1 - 0.0013 18.4 0.0 0.0031 17.2 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF900 PF05990.12 OAP62861.1 - 0.0013 18.3 0.0 0.0024 17.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Hydrolase_4 PF12146.8 OAP62861.1 - 0.0018 17.6 0.0 0.0041 16.4 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 AAA_22 PF13401.6 OAP62861.1 - 0.002 18.4 0.0 0.021 15.1 0.0 2.9 3 0 0 3 3 3 1 AAA domain DUF2075 PF09848.9 OAP62861.1 - 0.038 13.2 0.0 0.082 12.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Palm_thioest PF02089.15 OAP62861.1 - 0.081 12.8 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Lipase_3 PF01764.25 OAP62861.1 - 0.17 11.8 0.0 0.38 10.6 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) MeaB PF03308.16 OAP62861.1 - 0.17 10.9 0.0 0.32 9.9 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RNA_helicase PF00910.22 OAP62861.1 - 0.17 12.2 0.2 0.63 10.5 0.0 2.0 2 0 0 2 2 2 0 RNA helicase Fructosamin_kin PF03881.14 OAP62862.1 - 2e-33 115.9 0.0 2.5e-33 115.5 0.0 1.1 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 OAP62862.1 - 5.7e-11 42.8 0.1 1e-10 42.0 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 OAP62862.1 - 0.038 13.3 0.0 0.061 12.6 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase adh_short_C2 PF13561.6 OAP62864.1 - 8.9e-44 149.8 0.2 1.1e-43 149.5 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP62864.1 - 2e-35 122.0 0.2 2.7e-35 121.6 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAP62864.1 - 2.1e-06 27.7 0.1 3.2e-06 27.2 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAP62864.1 - 0.00037 20.0 0.0 0.0016 18.0 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 OAP62864.1 - 0.088 12.1 0.0 0.28 10.5 0.0 1.7 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GDP_Man_Dehyd PF16363.5 OAP62864.1 - 0.097 12.0 0.0 9.2 5.5 0.0 2.1 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Peptidase_M16_C PF05193.21 OAP62866.1 - 1.5e-49 168.5 0.0 2.9e-49 167.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 OAP62866.1 - 1.2e-39 135.7 0.0 1.9e-39 135.0 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) zf-RING_11 PF17123.5 OAP62867.1 - 1.1e-12 47.4 4.8 2.1e-12 46.6 4.8 1.5 1 0 0 1 1 1 1 RING-like zinc finger FHA PF00498.26 OAP62867.1 - 6.9e-12 45.5 0.0 1.3e-11 44.7 0.0 1.5 1 0 0 1 1 1 1 FHA domain zf-RING_2 PF13639.6 OAP62867.1 - 9.9e-08 32.2 6.3 2.1e-07 31.2 6.3 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 OAP62867.1 - 0.00053 19.9 5.2 0.00095 19.1 5.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 OAP62867.1 - 0.00086 19.1 6.9 0.0019 18.0 6.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Yop-YscD_cpl PF16697.5 OAP62867.1 - 0.00094 19.5 0.0 0.0022 18.3 0.0 1.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain zf-C3HC4 PF00097.25 OAP62867.1 - 0.0011 18.8 6.2 0.0023 17.8 6.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 OAP62867.1 - 0.0023 17.8 4.0 0.0044 16.9 4.0 1.5 1 0 0 1 1 1 1 PHD-finger zf-RING_UBOX PF13445.6 OAP62867.1 - 0.0047 16.9 6.8 0.0095 15.9 6.8 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 OAP62867.1 - 0.013 15.7 4.7 0.046 14.0 4.7 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 OAP62867.1 - 0.018 14.9 4.0 0.032 14.1 4.0 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 OAP62867.1 - 0.047 13.7 1.5 0.1 12.7 1.5 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING-like PF08746.11 OAP62867.1 - 0.37 11.1 4.2 0.74 10.2 4.2 1.5 1 0 0 1 1 1 0 RING-like domain Zn_ribbon_17 PF17120.5 OAP62867.1 - 6.4 6.5 6.9 1.7 8.3 3.6 1.8 2 0 0 2 2 1 0 Zinc-ribbon, C4HC2 type Alb1 PF09135.11 OAP62869.1 - 9.3e-22 77.9 9.0 9.3e-22 77.9 9.0 1.8 2 0 0 2 2 2 1 Alb1 Vps16_N PF04841.13 OAP62870.1 - 9.5e-100 334.2 0.0 1.2e-99 333.8 0.0 1.1 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.12 OAP62870.1 - 1.8e-87 293.4 0.0 2.4e-87 293.0 0.0 1.1 1 0 0 1 1 1 1 Vps16, C-terminal region ANAPC4_WD40 PF12894.7 OAP62870.1 - 0.0012 19.1 0.0 1 9.7 0.0 2.6 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain lci PF12197.8 OAP62870.1 - 0.057 13.2 0.1 0.17 11.7 0.1 1.8 1 0 0 1 1 1 0 Bacillus cereus group antimicrobial protein RCC1_2 PF13540.6 OAP62870.1 - 0.075 12.9 0.6 14 5.6 0.0 3.0 3 0 0 3 3 3 0 Regulator of chromosome condensation (RCC1) repeat AAA_lid_2 PF17863.1 OAP62871.1 - 1.8e-07 30.9 0.1 5.5e-07 29.3 0.0 1.9 2 0 0 2 2 2 1 AAA lid domain Abhydrolase_3 PF07859.13 OAP62872.1 - 1.2e-49 169.1 0.0 1.5e-49 168.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 OAP62872.1 - 2.4e-06 26.7 0.2 5.6e-06 25.5 0.2 1.4 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 OAP62872.1 - 0.00013 21.5 0.1 0.00065 19.2 0.1 1.9 2 0 0 2 2 2 1 Prolyl oligopeptidase family DLH PF01738.18 OAP62872.1 - 0.0018 17.9 0.0 0.024 14.2 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family AXE1 PF05448.12 OAP62872.1 - 0.0021 16.8 0.0 0.0033 16.2 0.0 1.3 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Say1_Mug180 PF10340.9 OAP62872.1 - 0.0033 16.3 0.0 0.0042 16.0 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Glyco_hydro_125 PF06824.11 OAP62874.1 - 5.6e-169 562.4 0.0 6.5e-169 562.2 0.0 1.0 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) Trehalase PF01204.18 OAP62874.1 - 0.05 12.4 0.0 0.081 11.7 0.0 1.2 1 0 0 1 1 1 0 Trehalase CDC27 PF09507.10 OAP62875.1 - 4.4e-71 240.5 23.9 1e-69 236.0 23.9 2.0 1 1 0 1 1 1 1 DNA polymerase subunit Cdc27 Fungal_trans PF04082.18 OAP62876.1 - 1.4e-10 40.7 0.4 1.1e-09 37.8 0.0 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF829 PF05705.14 OAP62877.1 - 1.6e-34 119.8 0.0 8.9e-33 114.2 0.0 2.3 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) TIP120 PF08623.10 OAP62878.1 - 9.7e-53 178.4 0.0 7.9e-51 172.2 0.0 3.1 2 0 0 2 2 2 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.6 OAP62878.1 - 2.8e-15 56.5 14.2 0.015 15.7 0.0 8.2 7 3 1 8 8 8 5 HEAT repeats HEAT PF02985.22 OAP62878.1 - 1.4e-14 52.9 13.2 0.058 13.7 0.0 11.1 10 0 0 10 10 10 4 HEAT repeat RTP1_C1 PF10363.9 OAP62878.1 - 1.5e-06 28.4 2.2 0.017 15.3 0.1 5.8 6 1 1 7 7 7 1 Required for nuclear transport of RNA pol II C-terminus 1 Cnd1 PF12717.7 OAP62878.1 - 5.5e-05 23.3 10.0 0.068 13.2 0.0 6.2 7 2 0 7 7 7 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 OAP62878.1 - 9.8e-05 22.9 2.6 0.093 13.3 0.0 5.5 6 1 0 6 6 5 1 Vacuolar 14 Fab1-binding region DRIM PF07539.12 OAP62878.1 - 0.00014 20.3 3.9 0.036 12.4 0.3 3.7 4 1 0 4 4 4 1 Down-regulated in metastasis HEAT_EZ PF13513.6 OAP62878.1 - 0.00016 22.1 24.1 2.4 8.8 0.0 11.3 12 2 2 14 14 14 2 HEAT-like repeat DUF3385 PF11865.8 OAP62878.1 - 0.0019 18.1 0.6 0.4 10.6 0.0 4.6 5 1 0 5 5 5 1 Domain of unknown function (DUF3385) CLASP_N PF12348.8 OAP62878.1 - 0.014 15.0 0.3 6.2 6.3 0.0 4.3 3 1 1 4 4 4 0 CLASP N terminal HEAT_PBS PF03130.16 OAP62878.1 - 0.94 10.3 7.9 19 6.3 0.0 5.7 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat MMS19_N PF14500.6 OAP62878.1 - 1.1 8.8 5.2 40 3.7 0.0 4.2 5 0 0 5 5 5 0 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.8 OAP62878.1 - 5.3 6.0 13.6 25 3.8 0.2 5.4 5 1 1 6 6 6 0 RNAPII transcription regulator C-terminal SpoIIIAH PF12685.7 OAP62879.1 - 0.0015 18.4 13.4 0.0072 16.2 13.4 1.9 1 1 0 1 1 1 1 SpoIIIAH-like protein Presenilin PF01080.17 OAP62879.1 - 0.44 9.3 11.0 0.47 9.2 11.0 1.2 1 0 0 1 1 1 0 Presenilin SAPS PF04499.15 OAP62879.1 - 0.66 8.7 8.5 0.74 8.5 8.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein ORC6 PF05460.13 OAP62879.1 - 0.73 9.0 10.7 0.84 8.8 10.7 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Mitofilin PF09731.9 OAP62879.1 - 1.1 8.0 15.3 1.3 7.8 15.3 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Menin PF05053.13 OAP62879.1 - 3.4 5.9 7.8 3.9 5.7 7.8 1.2 1 0 0 1 1 1 0 Menin Neur_chan_memb PF02932.16 OAP62879.1 - 5.3 7.0 4.7 6.6 6.7 4.7 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Macoilin PF09726.9 OAP62879.1 - 6.3 5.2 8.2 6.9 5.1 8.2 1.1 1 0 0 1 1 1 0 Macoilin family Nop14 PF04147.12 OAP62879.1 - 7.1 4.7 24.3 8.2 4.5 24.3 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 OAP62879.1 - 7.4 4.7 18.6 8.8 4.5 18.6 1.1 1 0 0 1 1 1 0 CDC45-like protein TRAM_LAG1_CLN8 PF03798.16 OAP62880.1 - 3.4e-37 128.1 22.3 6e-37 127.3 22.3 1.4 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.11 OAP62880.1 - 8.9e-25 86.1 0.0 8.9e-25 86.1 0.0 2.0 2 0 0 2 2 2 1 TRAM1-like protein Ferric_reduct PF01794.19 OAP62881.1 - 2.1e-24 86.1 12.7 2.1e-24 86.1 12.7 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 OAP62881.1 - 2.7e-06 27.4 0.0 0.0004 20.5 0.0 2.9 2 1 0 2 2 2 1 FAD-binding domain NAD_binding_6 PF08030.12 OAP62881.1 - 3.4e-06 27.3 1.4 0.0052 16.9 0.0 2.4 1 1 1 2 2 2 2 Ferric reductase NAD binding domain DUF2207 PF09972.9 OAP62881.1 - 5.9 5.5 6.9 4.4 5.9 0.5 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) YTH PF04146.15 OAP62882.1 - 3.5e-38 131.2 0.0 5.4e-38 130.5 0.0 1.3 1 0 0 1 1 1 1 YT521-B-like domain RRM_1 PF00076.22 OAP62882.1 - 0.086 12.7 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 OAP62882.1 - 0.13 12.0 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Rrp7 RRM-like N-terminal domain peroxidase PF00141.23 OAP62883.1 - 5.6e-26 91.6 0.0 1.2e-25 90.6 0.0 1.5 1 0 0 1 1 1 1 Peroxidase Ferric_reduct PF01794.19 OAP62884.1 - 5.8e-22 78.1 12.9 5.8e-22 78.1 12.9 2.2 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 OAP62884.1 - 1.4e-15 57.3 0.0 2.9e-15 56.3 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 OAP62884.1 - 3.5e-07 30.5 0.0 6.2e-07 29.7 0.0 1.5 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_6 PF00970.24 OAP62884.1 - 0.12 12.7 0.0 0.25 11.7 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain DUF1270 PF06900.11 OAP62884.1 - 1 9.8 5.7 0.35 11.3 2.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1270) Fasciclin PF02469.22 OAP62885.1 - 9.2e-22 77.6 0.1 1.4e-09 38.2 0.0 2.4 2 0 0 2 2 2 2 Fasciclin domain Vut_1 PF02592.15 OAP62885.1 - 0.053 13.8 0.8 0.27 11.6 0.1 2.3 2 0 0 2 2 2 0 Putative vitamin uptake transporter MFS_1 PF07690.16 OAP62886.1 - 3.8e-15 55.7 56.7 1.8e-13 50.2 30.9 2.7 2 1 1 3 3 3 2 Major Facilitator Superfamily Pox_A14 PF05767.12 OAP62886.1 - 5.4 7.3 6.5 1.3 9.2 0.5 3.0 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 Aldo_ket_red PF00248.21 OAP62887.1 - 1.3e-33 116.4 0.0 1.7e-33 116.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family ADH_N PF08240.12 OAP62888.1 - 1.7e-20 72.9 1.1 2.3e-20 72.5 1.1 1.2 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain FMO-like PF00743.19 OAP62890.1 - 4.5e-16 58.4 0.9 1.8e-15 56.4 0.1 2.2 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OAP62890.1 - 1.4e-10 41.2 0.0 3e-10 40.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 OAP62890.1 - 1.4e-06 27.7 0.0 0.001 18.3 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 OAP62890.1 - 1.6e-06 28.2 0.0 2.2e-05 24.5 0.0 2.6 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 OAP62890.1 - 6.8e-06 25.5 0.0 0.00019 20.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAP62890.1 - 0.0021 17.4 0.0 0.011 15.0 0.0 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAP62890.1 - 0.12 11.9 0.0 1.9 7.9 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.17 OAP62890.1 - 0.16 11.2 0.0 1.1 8.5 0.0 2.1 2 0 0 2 2 2 0 Thi4 family p450 PF00067.22 OAP62891.1 - 5.4e-59 200.1 0.0 7.5e-59 199.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 HET PF06985.11 OAP62892.1 - 3.5e-22 79.3 0.1 6.6e-22 78.4 0.1 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) zf-C2H2 PF00096.26 OAP62893.1 - 5.3e-08 32.9 21.2 0.00051 20.3 1.5 5.0 4 1 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAP62893.1 - 7.2e-08 32.6 14.6 0.0007 20.2 0.6 4.1 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 OAP62893.1 - 3.6e-05 23.7 1.6 0.00016 21.6 0.1 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger zinc_ribbon_5 PF13719.6 OAP62893.1 - 6.4e-05 22.6 1.9 1.1 9.1 0.0 3.5 3 0 0 3 3 3 2 zinc-ribbon domain zf-BED PF02892.15 OAP62893.1 - 0.00012 22.0 10.0 0.052 13.6 0.2 4.0 2 2 2 4 4 4 2 BED zinc finger zf-C2H2_2 PF12756.7 OAP62893.1 - 0.00047 20.4 2.9 0.035 14.4 0.8 2.4 1 1 0 2 2 2 1 C2H2 type zinc-finger (2 copies) GAGA PF09237.11 OAP62893.1 - 0.005 16.6 3.6 0.0059 16.4 0.3 2.7 3 0 0 3 3 3 1 GAGA factor zf-Di19 PF05605.12 OAP62893.1 - 0.038 14.3 11.0 0.043 14.1 0.3 3.0 2 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_3rep PF18868.1 OAP62893.1 - 0.038 14.6 1.2 2.7 8.7 0.1 2.3 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats PyrI_C PF02748.15 OAP62893.1 - 0.041 13.8 4.4 0.45 10.5 0.0 3.1 2 1 1 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zinc-ribbons_6 PF07191.12 OAP62893.1 - 0.05 13.6 3.3 2.3 8.2 1.1 2.5 1 1 0 2 2 2 0 zinc-ribbons FOXP-CC PF16159.5 OAP62893.1 - 0.071 13.7 0.5 0.72 10.5 0.0 2.5 3 0 0 3 3 3 0 FOXP coiled-coil domain zinc_ribbon_4 PF13717.6 OAP62893.1 - 0.15 12.0 7.1 8.7 6.4 0.3 3.7 4 0 0 4 4 4 0 zinc-ribbon domain DUF629 PF04780.12 OAP62893.1 - 0.46 9.0 1.5 11 4.4 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF629) TF_Zn_Ribbon PF08271.12 OAP62893.1 - 0.59 9.7 0.1 0.59 9.7 0.1 2.6 2 1 0 2 2 2 0 TFIIB zinc-binding zf-C2H2_7 PF15269.6 OAP62893.1 - 0.66 10.1 6.4 4.4 7.5 2.7 2.3 2 0 0 2 2 2 0 Zinc-finger zf-H2C2_5 PF13909.6 OAP62893.1 - 0.78 9.6 29.4 0.25 11.2 1.0 4.8 5 1 0 5 5 5 0 C2H2-type zinc-finger domain zf-C2HE PF16278.5 OAP62893.1 - 1 9.9 8.5 1.3 9.5 0.1 3.4 2 1 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger Zn_ribbon_SprT PF17283.2 OAP62893.1 - 2.9 7.9 16.1 0.93 9.5 0.4 3.6 3 1 0 3 3 3 0 SprT-like zinc ribbon domain zinc_ribbon_9 PF14369.6 OAP62893.1 - 4.2 7.7 7.5 53 4.2 5.0 3.1 2 1 1 3 3 3 0 zinc-ribbon DZR PF12773.7 OAP62893.1 - 6.5 6.9 11.5 14 5.8 7.8 2.5 1 1 1 2 2 2 0 Double zinc ribbon RRM_1 PF00076.22 OAP62894.1 - 1.7e-26 91.8 0.4 1.9e-12 46.8 0.2 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OAP62894.1 - 3.5e-06 26.8 0.0 0.0083 16.0 0.1 2.2 2 0 0 2 2 2 2 Occluded RNA-recognition motif RRM_5 PF13893.6 OAP62894.1 - 0.00013 21.6 0.0 0.0024 17.5 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4523 PF15023.6 OAP62894.1 - 0.0015 18.4 0.1 0.0039 17.0 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF4523) DUF1027 PF06265.11 OAP62894.1 - 0.056 13.4 0.0 0.099 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1027) PHM7_cyt PF14703.6 OAP62894.1 - 0.65 10.2 2.2 5.6 7.2 0.0 3.1 3 1 1 4 4 4 0 Cytosolic domain of 10TM putative phosphate transporter ATP-synt_D PF01813.17 OAP62895.1 - 1.7e-71 240.2 1.3 2e-71 239.9 1.3 1.1 1 0 0 1 1 1 1 ATP synthase subunit D TPR_14 PF13428.6 OAP62897.1 - 8e-18 63.6 14.8 0.033 15.0 0.0 12.1 12 1 1 13 13 12 3 Tetratricopeptide repeat Suf PF05843.14 OAP62897.1 - 1e-13 52.0 3.6 0.0052 16.8 0.1 5.6 3 1 1 6 6 6 3 Suppressor of forked protein (Suf) TPR_8 PF13181.6 OAP62897.1 - 3.6e-08 33.0 1.2 0.18 12.1 0.1 6.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_15 PF13429.6 OAP62897.1 - 7.4e-08 31.9 3.7 0.00011 21.6 0.0 4.2 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 OAP62897.1 - 1.6e-06 28.3 2.1 3.3 8.0 0.1 6.4 6 1 1 7 7 7 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 OAP62897.1 - 4e-06 26.8 9.9 0.37 10.8 0.0 6.6 7 1 0 7 7 7 2 Mad3/BUB1 homology region 1 TPR_2 PF07719.17 OAP62897.1 - 1.1e-05 25.2 8.3 1.3 9.3 0.0 7.4 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_19 PF14559.6 OAP62897.1 - 0.00012 22.5 8.2 0.082 13.4 0.1 6.2 6 1 1 7 7 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 OAP62897.1 - 0.00029 21.0 7.5 0.11 12.9 0.1 6.5 8 0 0 8 8 7 1 Tetratricopeptide repeat RPN7 PF10602.9 OAP62897.1 - 0.001 18.8 0.2 0.022 14.5 0.1 3.1 3 1 0 3 3 3 1 26S proteasome subunit RPN7 NRDE-2 PF08424.10 OAP62897.1 - 0.0035 16.5 8.7 0.15 11.2 1.4 5.3 2 2 1 3 3 3 1 NRDE-2, necessary for RNA interference MIT PF04212.18 OAP62897.1 - 0.13 12.4 0.0 1.2 9.3 0.0 2.7 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_4 PF07721.14 OAP62897.1 - 0.34 11.7 14.7 1.4 9.8 0.0 5.1 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 OAP62897.1 - 0.39 11.4 9.6 5.9 7.8 0.1 6.2 7 0 0 7 7 5 0 Tetratricopeptide repeat HAT PF02184.16 OAP62897.1 - 0.62 10.1 14.6 3.7 7.6 0.0 6.2 7 0 0 7 7 6 0 HAT (Half-A-TPR) repeat Aldedh PF00171.22 OAP62898.1 - 2.4e-120 402.2 0.0 2.8e-120 401.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 OAP62898.1 - 0.18 10.8 0.0 0.41 9.6 0.0 1.5 2 0 0 2 2 2 0 Acyl-CoA reductase (LuxC) Chromate_transp PF02417.15 OAP62900.1 - 1.9e-58 197.1 36.0 5.6e-35 120.8 13.0 2.4 3 0 0 3 3 3 2 Chromate transporter Abhydrolase_6 PF12697.7 OAP62901.1 - 4.9e-23 82.9 1.4 6.4e-23 82.5 1.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAP62901.1 - 4.3e-14 52.4 0.0 6.5e-14 51.8 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OAP62901.1 - 1.1e-13 51.4 0.6 1.2e-11 44.7 0.6 2.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold LIDHydrolase PF10230.9 OAP62901.1 - 0.0031 17.1 0.0 0.01 15.4 0.0 1.8 1 1 0 1 1 1 1 Lipid-droplet associated hydrolase Ser_hydrolase PF06821.13 OAP62901.1 - 0.034 14.0 0.2 0.31 10.9 0.0 2.1 2 0 0 2 2 2 0 Serine hydrolase DUF3565 PF12088.8 OAP62901.1 - 0.068 13.1 0.5 1.2 9.1 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3565) DLH PF01738.18 OAP62901.1 - 0.073 12.6 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family TPR_12 PF13424.6 OAP62902.1 - 0.00056 20.2 5.4 0.03 14.6 0.3 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_MalT PF17874.1 OAP62902.1 - 0.012 15.0 0.1 0.012 15.0 0.1 2.6 2 1 1 3 3 3 0 MalT-like TPR region TPR_2 PF07719.17 OAP62902.1 - 0.09 12.9 0.1 0.25 11.6 0.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_10 PF13374.6 OAP62902.1 - 0.11 12.4 0.7 3.9 7.5 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 OAP62902.1 - 0.43 11.5 5.2 30 5.8 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Cpn60_TCP1 PF00118.24 OAP62903.1 - 5.7e-152 506.8 18.7 6.5e-152 506.6 18.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PHO4 PF01384.20 OAP62904.1 - 1.9e-101 339.5 14.9 2.2e-101 339.3 14.9 1.0 1 0 0 1 1 1 1 Phosphate transporter family EBP50_C PF09007.11 OAP62904.1 - 0.024 15.6 0.1 0.041 14.9 0.1 1.3 1 0 0 1 1 1 0 EBP50, C-terminal ProRS-C_1 PF09180.11 OAP62905.1 - 4.3e-23 81.3 0.4 9.6e-23 80.2 0.2 1.7 2 0 0 2 2 2 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.25 OAP62905.1 - 1.9e-19 70.3 0.0 3.1e-19 69.6 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 OAP62905.1 - 8.8e-13 48.2 0.0 2.3e-12 46.9 0.0 1.8 1 0 0 1 1 1 1 Anticodon binding domain DUF116 PF01976.17 OAP62905.1 - 0.17 11.4 0.0 0.31 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF116 Acetyltransf_1 PF00583.25 OAP62906.1 - 5.7e-07 29.8 0.0 1e-06 29.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OAP62906.1 - 0.011 15.7 0.0 0.018 15.0 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Pho86 PF11124.8 OAP62906.1 - 0.068 12.6 0.1 0.097 12.1 0.1 1.2 1 0 0 1 1 1 0 Inorganic phosphate transporter Pho86 Acetyltransf_7 PF13508.7 OAP62906.1 - 0.11 12.9 0.0 0.22 11.9 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Metallophos PF00149.28 OAP62907.1 - 2e-32 113.3 0.0 2.8e-23 83.5 0.0 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase COA2 PF17051.5 OAP62908.1 - 0.043 13.9 0.1 0.093 12.8 0.1 1.8 1 1 0 1 1 1 0 Cytochrome C oxidase assembly factor 2 Methyltransf_33 PF10017.9 OAP62910.1 - 5e-85 285.4 0.8 7.5e-85 284.8 0.8 1.2 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.16 OAP62910.1 - 9.5e-19 68.0 1.9 9.1e-10 38.5 0.3 2.3 2 0 0 2 2 2 2 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.7 OAP62910.1 - 0.0017 18.9 1.5 0.006 17.1 0.6 2.4 2 1 0 2 2 2 1 DinB superfamily RhoGEF PF00621.20 OAP62911.1 - 6.9e-12 46.0 0.2 1.3e-11 45.1 0.2 1.3 1 0 0 1 1 1 1 RhoGEF domain DUF3507 PF12015.8 OAP62911.1 - 3.2e-06 27.0 0.0 5.7e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3507) WD40 PF00400.32 OAP62912.1 - 7.5e-16 58.2 1.2 0.002 18.9 0.5 6.4 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAP62912.1 - 1.5e-06 28.4 0.0 0.0014 18.9 0.0 4.4 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OAP62912.1 - 0.015 13.9 0.0 0.14 10.8 0.0 2.1 1 1 1 2 2 2 0 Nucleoporin Nup120/160 S1 PF00575.23 OAP62913.1 - 4.1e-74 244.9 32.1 1e-14 54.6 2.8 12.4 12 0 0 12 12 12 10 S1 RNA binding domain Suf PF05843.14 OAP62913.1 - 9.7e-11 42.2 8.4 0.0013 18.8 0.1 4.4 2 1 2 4 4 4 3 Suppressor of forked protein (Suf) TPR_14 PF13428.6 OAP62913.1 - 8.3e-08 32.4 0.5 0.13 13.1 0.0 4.2 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 OAP62913.1 - 2.2e-05 24.9 0.0 0.17 12.5 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 OAP62913.1 - 0.00071 19.8 0.7 0.7 10.2 0.6 3.4 2 1 1 3 3 3 1 Tetratricopeptide repeat RNase_II_C_S1 PF18614.1 OAP62913.1 - 0.00095 19.1 17.8 0.33 10.9 0.0 6.9 8 1 0 8 8 8 2 RNase II-type exonuclease C-terminal S1 domain TPR_15 PF13429.6 OAP62913.1 - 0.037 13.2 0.2 0.42 9.8 0.1 2.0 1 1 1 2 2 2 0 Tetratricopeptide repeat Wzy_C_2 PF11846.8 OAP62913.1 - 0.053 13.5 0.1 0.12 12.3 0.1 1.6 1 0 0 1 1 1 0 Virulence factor membrane-bound polymerase, C-terminal S1_2 PF13509.6 OAP62913.1 - 0.057 13.5 0.3 2.1 8.5 0.0 3.8 4 0 0 4 4 4 0 S1 domain TPR_7 PF13176.6 OAP62913.1 - 0.48 10.6 0.0 0.48 10.6 0.0 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat DNA_ligase_A_M PF01068.21 OAP62915.1 - 9.9e-49 165.7 0.0 2.2e-48 164.6 0.0 1.6 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 OAP62915.1 - 5.8e-43 147.2 0.0 2.1e-42 145.4 0.0 2.0 2 0 0 2 2 2 1 DNA ligase N terminus BRCT_2 PF16589.5 OAP62915.1 - 3.5e-17 62.6 0.3 1.7e-12 47.6 0.0 2.8 3 0 0 3 3 3 2 BRCT domain, a BRCA1 C-terminus domain RNA_ligase PF09414.10 OAP62915.1 - 1.4e-16 61.2 0.0 3.5e-16 59.9 0.0 1.7 1 0 0 1 1 1 1 RNA ligase DNA_ligase_A_C PF04679.15 OAP62915.1 - 6.5e-14 52.3 1.2 1.3e-11 44.9 0.0 3.6 4 0 0 4 4 4 1 ATP dependent DNA ligase C terminal region BRCT PF00533.26 OAP62915.1 - 1.3e-06 28.7 2.8 1.4e-06 28.6 0.0 2.5 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain DNA_ligase_IV PF11411.8 OAP62915.1 - 0.00019 21.5 0.1 0.00056 20.0 0.1 1.8 1 0 0 1 1 1 1 DNA ligase IV LIG3_BRCT PF16759.5 OAP62915.1 - 0.00027 21.2 0.2 0.33 11.3 0.0 2.7 2 0 0 2 2 2 2 DNA ligase 3 BRCT domain RTT107_BRCT_5 PF16770.5 OAP62915.1 - 0.028 14.3 0.0 2.4 8.1 0.0 2.5 2 0 0 2 2 2 0 Regulator of Ty1 transposition protein 107 BRCT domain DUF1178 PF06676.11 OAP62915.1 - 0.079 13.4 0.2 15 6.0 1.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1178) EF-hand_4 PF12763.7 OAP62916.1 - 0.0021 18.0 0.0 0.0042 17.0 0.0 1.4 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand CAP_N PF01213.19 OAP62917.1 - 0.21 11.0 3.6 0.38 10.2 3.6 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal CPSase_L_D2 PF02786.17 OAP62918.1 - 3.9e-114 379.4 0.4 2e-83 279.1 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain GATase PF00117.28 OAP62918.1 - 1.9e-47 161.5 0.0 6.5e-47 159.8 0.0 2.0 2 0 0 2 2 2 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.22 OAP62918.1 - 3.6e-47 159.4 0.0 7.2e-47 158.4 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain OTCace_N PF02729.21 OAP62918.1 - 1.8e-43 148.1 0.0 4.2e-43 146.9 0.0 1.7 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_D3 PF02787.19 OAP62918.1 - 9.8e-40 135.7 0.0 2.5e-39 134.4 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.24 OAP62918.1 - 6.2e-30 104.4 0.0 1.5e-29 103.1 0.0 1.8 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain MGS PF02142.22 OAP62918.1 - 5.3e-21 74.6 0.0 2.6e-20 72.4 0.0 2.3 2 0 0 2 2 1 1 MGS-like domain Dala_Dala_lig_C PF07478.13 OAP62918.1 - 1.1e-17 64.3 0.4 5.9e-09 35.8 0.2 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 OAP62918.1 - 2.9e-16 59.5 0.1 4.5e-08 32.9 0.1 2.5 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 OAP62918.1 - 2.5e-10 40.2 0.0 1.7e-05 24.6 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Peptidase_C26 PF07722.13 OAP62918.1 - 9e-06 25.6 0.6 0.00093 19.0 0.1 2.8 2 1 0 2 2 2 1 Peptidase C26 ATP-grasp_3 PF02655.14 OAP62918.1 - 1.6e-05 25.0 0.4 0.052 13.6 0.1 2.7 2 0 0 2 2 2 2 ATP-grasp domain DJ-1_PfpI PF01965.24 OAP62918.1 - 0.00012 21.9 0.2 0.065 13.0 0.0 4.1 5 0 0 5 5 4 1 DJ-1/PfpI family RimK PF08443.11 OAP62918.1 - 0.00054 19.6 0.1 0.24 11.0 0.1 2.6 2 0 0 2 2 2 2 RimK-like ATP-grasp domain ID PF18543.1 OAP62918.1 - 0.0098 15.9 0.0 0.35 10.9 0.0 2.7 2 0 0 2 2 2 1 Intracellular delivery domain Synaptobrevin PF00957.21 OAP62920.1 - 5.3e-32 109.5 0.0 7.3e-32 109.0 0.0 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 OAP62920.1 - 9e-29 99.4 0.1 1.7e-28 98.5 0.1 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain RRM_1 PF00076.22 OAP62922.1 - 1.3e-14 53.8 0.0 3.2e-14 52.5 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 OAP62922.1 - 3.4e-08 33.9 1.2 3.4e-08 33.9 1.2 2.7 2 1 1 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 RRM_occluded PF16842.5 OAP62922.1 - 2.8e-05 23.9 0.0 4.5e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Occluded RNA-recognition motif RRM_7 PF16367.5 OAP62922.1 - 0.019 15.1 0.0 0.035 14.2 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif Snf7 PF03357.21 OAP62923.1 - 6.8e-25 87.7 6.3 6.8e-25 87.7 6.3 1.8 1 1 1 2 2 2 1 Snf7 Gon7 PF08738.10 OAP62923.1 - 0.087 12.9 2.7 0.24 11.5 0.7 2.4 2 0 0 2 2 2 0 Gon7 family CS PF04969.16 OAP62924.1 - 5e-05 24.2 0.1 8e-05 23.6 0.1 1.3 1 0 0 1 1 1 1 CS domain LtrA PF06772.11 OAP62925.1 - 5.6e-35 121.2 28.1 6.9e-35 120.9 28.1 1.1 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) DUF1129 PF06570.11 OAP62925.1 - 2.2 7.7 8.7 0.14 11.7 3.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) DFRP_C PF16543.5 OAP62927.1 - 8e-26 90.4 8.2 8e-26 90.4 8.2 4.2 3 2 1 4 4 4 1 DRG Family Regulatory Proteins, Tma46 zf-CCCH PF00642.24 OAP62927.1 - 1.2e-06 28.2 2.9 1.2e-06 28.2 2.9 2.6 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 OAP62927.1 - 7.5e-05 22.4 12.4 0.00063 19.5 3.5 3.3 3 0 0 3 3 3 1 CCCH-type zinc finger Torus PF16131.5 OAP62927.1 - 0.00039 21.1 17.1 0.00068 20.3 6.3 3.3 2 1 1 3 3 3 2 Torus domain zf_CCCH_4 PF18345.1 OAP62927.1 - 0.00054 19.9 9.6 0.00054 19.9 9.6 3.3 3 0 0 3 3 3 1 Zinc finger domain zf-CCCH_3 PF15663.5 OAP62927.1 - 0.017 15.4 4.2 0.24 11.6 0.1 2.8 3 0 0 3 3 3 0 Zinc-finger containing family zf-CCCH_2 PF14608.6 OAP62927.1 - 0.056 13.9 15.3 0.11 13.0 5.8 2.9 2 1 0 2 2 2 0 RNA-binding, Nab2-type zinc finger MAS20 PF02064.15 OAP62930.1 - 1.7e-44 151.1 0.1 2e-44 150.8 0.1 1.0 1 0 0 1 1 1 1 MAS20 protein import receptor PsbN PF02468.15 OAP62930.1 - 0.19 11.6 2.1 0.35 10.8 2.1 1.5 1 0 0 1 1 1 0 Photosystem II reaction centre N protein (psbN) YolD PF08863.10 OAP62930.1 - 0.29 11.2 2.7 0.44 10.6 2.7 1.3 1 0 0 1 1 1 0 YolD-like protein Cu_amine_oxid PF01179.20 OAP62931.1 - 2.2e-160 534.1 0.0 2.9e-160 533.7 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.16 OAP62931.1 - 5e-07 29.9 0.1 1.1e-06 28.8 0.1 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.16 OAP62931.1 - 0.0019 18.6 0.0 0.0054 17.1 0.0 1.8 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Aldedh PF00171.22 OAP62932.1 - 3.9e-179 596.0 0.5 4.4e-179 595.8 0.5 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Hemerythrin PF01814.23 OAP62933.1 - 3.7e-10 40.5 2.7 5.4e-10 40.0 2.7 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain ABC1 PF03109.16 OAP62933.1 - 0.031 14.4 0.0 1.5 9.0 0.0 2.1 2 0 0 2 2 2 0 ABC1 family DUF775 PF05603.12 OAP62934.1 - 6.1e-57 192.4 0.0 7e-57 192.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) ABC_membrane PF00664.23 OAP62935.1 - 5e-80 269.1 26.5 2.9e-44 151.8 6.7 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 OAP62935.1 - 1.7e-65 219.7 0.0 2.4e-32 112.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 OAP62935.1 - 3.9e-12 46.1 0.3 0.0026 17.2 0.1 4.4 2 2 2 4 4 4 3 RecF/RecN/SMC N terminal domain Rad17 PF03215.15 OAP62935.1 - 1.1e-08 35.3 0.0 0.0009 19.2 0.0 3.2 3 0 0 3 3 3 2 Rad17 P-loop domain ABC_ATPase PF09818.9 OAP62935.1 - 2.7e-08 33.1 0.0 0.012 14.4 0.0 3.6 4 1 0 4 4 4 2 Predicted ATPase of the ABC class AAA_29 PF13555.6 OAP62935.1 - 6.5e-08 32.2 0.1 0.0045 16.7 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 OAP62935.1 - 1.2e-07 32.1 0.9 0.018 15.3 0.1 3.6 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.6 OAP62935.1 - 2.8e-07 31.1 3.8 0.025 15.0 1.3 3.6 2 2 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 OAP62935.1 - 4.4e-07 30.6 0.1 0.049 14.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 OAP62935.1 - 1.3e-06 28.4 0.0 0.045 13.7 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_21 PF13304.6 OAP62935.1 - 2.6e-06 27.5 0.5 0.49 10.1 0.0 4.3 3 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 OAP62935.1 - 8.8e-06 25.7 0.0 0.074 12.7 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain SbcCD_C PF13558.6 OAP62935.1 - 4.6e-05 23.6 2.1 0.36 11.1 0.1 3.7 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit Zeta_toxin PF06414.12 OAP62935.1 - 5.4e-05 22.5 0.0 0.54 9.5 0.0 3.2 3 0 0 3 3 3 2 Zeta toxin AAA_18 PF13238.6 OAP62935.1 - 0.00014 22.4 0.0 0.056 14.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 OAP62935.1 - 0.00022 21.0 0.4 1.1 8.9 0.0 3.8 3 1 0 3 3 3 1 AAA domain AAA_28 PF13521.6 OAP62935.1 - 0.0007 19.9 0.2 0.082 13.1 0.1 2.8 2 0 0 2 2 2 1 AAA domain ATP-synt_ab PF00006.25 OAP62935.1 - 0.00072 19.3 1.4 0.48 10.0 0.0 3.4 3 1 0 3 3 3 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_25 PF13481.6 OAP62935.1 - 0.00072 19.2 0.1 0.86 9.1 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_5 PF07728.14 OAP62935.1 - 0.00073 19.6 0.0 0.4 10.7 0.0 2.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) PRK PF00485.18 OAP62935.1 - 0.0011 18.7 0.0 0.8 9.4 0.0 2.5 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family IstB_IS21 PF01695.17 OAP62935.1 - 0.0013 18.5 0.3 6.2 6.5 0.0 3.4 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA PF00004.29 OAP62935.1 - 0.0013 19.1 0.4 3.8 7.9 0.0 3.5 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 OAP62935.1 - 0.0019 18.6 0.0 1.7 9.1 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_7 PF12775.7 OAP62935.1 - 0.002 17.7 0.0 1.4 8.4 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_14 PF13173.6 OAP62935.1 - 0.0045 17.0 0.0 3.1 7.8 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_24 PF13479.6 OAP62935.1 - 0.007 16.1 0.1 0.32 10.7 0.1 2.6 2 1 1 3 3 3 1 AAA domain APS_kinase PF01583.20 OAP62935.1 - 0.0085 16.0 0.0 3.4 7.5 0.0 2.5 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_33 PF13671.6 OAP62935.1 - 0.024 14.8 0.1 5.1 7.3 0.0 2.8 2 0 0 2 2 2 0 AAA domain dNK PF01712.19 OAP62935.1 - 0.053 13.4 0.1 3.7 7.3 0.1 2.6 2 0 0 2 2 2 0 Deoxynucleoside kinase DUF87 PF01935.17 OAP62935.1 - 0.054 13.6 0.0 2.5 8.2 0.0 2.7 2 0 0 2 2 2 0 Helicase HerA, central domain MMR_HSR1 PF01926.23 OAP62935.1 - 0.078 13.1 0.1 17 5.5 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase G-alpha PF00503.20 OAP62935.1 - 0.22 10.6 0.0 11 5.0 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit NTPase_1 PF03266.15 OAP62935.1 - 0.25 11.2 1.4 1.3 8.9 0.1 2.5 3 0 0 3 3 2 0 NTPase DUF4743 PF15916.5 OAP62936.1 - 1.3e-10 41.3 0.0 2.3e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4743) NUDIX PF00293.28 OAP62936.1 - 1.8e-10 41.0 0.0 3.8e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain RNA_pol_Rpb8 PF03870.15 OAP62937.1 - 8.3e-44 149.2 0.2 9.3e-44 149.0 0.2 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 RNA_pol_RpbG PF16992.5 OAP62937.1 - 0.00019 21.5 0.2 0.054 13.5 0.1 2.1 1 1 1 2 2 2 2 DNA-directed RNA polymerase, subunit G PAXNEB PF05625.11 OAP62938.1 - 1.3e-109 366.7 0.0 1.5e-109 366.5 0.0 1.0 1 0 0 1 1 1 1 PAXNEB protein tRNA_int_endo PF01974.17 OAP62940.1 - 4.8e-15 55.4 0.0 9.9e-15 54.4 0.0 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain UPF0086 PF01868.16 OAP62941.1 - 1.3e-28 98.7 0.0 2e-28 98.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function UPF0086 MFS_1 PF07690.16 OAP62942.1 - 1.5e-07 30.7 20.7 1.5e-07 30.7 20.7 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 OAP62942.1 - 8.5e-05 22.3 5.1 0.00026 20.7 5.1 1.8 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 GlpM PF06942.12 OAP62942.1 - 0.21 12.0 2.2 0.52 10.8 0.8 2.4 2 0 0 2 2 2 0 GlpM protein Polysacc_deac_1 PF01522.21 OAP62943.1 - 9.2e-21 74.0 0.0 1.5e-20 73.4 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 OAP62943.1 - 8e-11 42.0 0.2 2.7e-10 40.3 0.2 1.9 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) Glyco_hydro_57 PF03065.15 OAP62943.1 - 0.0073 15.6 0.1 0.014 14.6 0.0 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 57 Methyltransf_31 PF13847.6 OAP62944.1 - 7.9e-26 90.7 0.0 1.1e-25 90.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAP62944.1 - 8.6e-22 77.6 0.0 1.6e-21 76.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAP62944.1 - 8.7e-21 74.5 0.0 1.7e-20 73.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAP62944.1 - 1.9e-15 56.8 0.0 2.9e-15 56.3 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 OAP62944.1 - 8e-13 49.0 0.0 1.2e-12 48.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAP62944.1 - 1.7e-09 37.8 0.0 2.2e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OAP62944.1 - 6e-06 25.9 0.0 1e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain MetW PF07021.12 OAP62944.1 - 4e-05 23.3 0.0 6.6e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.6 OAP62944.1 - 6.1e-05 23.1 0.0 8.8e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 OAP62944.1 - 0.00014 21.2 0.0 0.0002 20.7 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_9 PF08003.11 OAP62944.1 - 0.0005 19.1 0.0 0.0007 18.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) PrmA PF06325.13 OAP62944.1 - 0.00051 19.5 0.0 0.00066 19.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.17 OAP62944.1 - 0.00055 19.4 0.0 0.00098 18.6 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase PCMT PF01135.19 OAP62944.1 - 0.00094 19.0 0.0 0.0013 18.5 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF938 PF06080.12 OAP62944.1 - 0.016 15.0 0.0 0.026 14.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) CheR PF01739.18 OAP62944.1 - 0.017 14.6 0.0 2.5 7.5 0.0 2.2 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain Methyltransf_8 PF05148.15 OAP62944.1 - 0.025 14.4 0.0 0.077 12.8 0.0 1.7 1 1 0 1 1 1 0 Hypothetical methyltransferase RrnaAD PF00398.20 OAP62944.1 - 0.057 12.5 0.0 0.077 12.1 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_3 PF01596.17 OAP62944.1 - 0.086 12.0 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase UPF0020 PF01170.18 OAP62944.1 - 0.18 11.5 0.0 0.62 9.7 0.0 1.8 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 Met_10 PF02475.16 OAP62944.1 - 0.2 11.4 0.0 0.3 10.8 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Ceramidase PF05875.12 OAP62945.1 - 0.1 12.0 6.9 0.1 12.0 0.4 2.2 2 0 0 2 2 2 0 Ceramidase Trp_oprn_chp PF09534.10 OAP62945.1 - 0.34 10.7 3.9 0.82 9.4 0.1 2.4 2 1 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF981 PF06168.11 OAP62945.1 - 0.9 9.4 12.7 1.4 8.8 6.5 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF981) DUF2070 PF09843.9 OAP62945.1 - 1.6 6.9 7.7 1.3 7.2 1.2 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) Zn_clus PF00172.18 OAP62946.1 - 3.9e-07 30.1 11.0 8.1e-07 29.1 11.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MIT PF04212.18 OAP62946.1 - 0.1 12.6 0.1 0.31 11.1 0.1 1.8 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain RIX1 PF08167.12 OAP62946.1 - 0.11 12.3 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 rRNA processing/ribosome biogenesis WD40 PF00400.32 OAP62947.1 - 5.9e-13 49.1 7.7 0.014 16.3 0.0 6.5 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAP62947.1 - 5.8e-07 29.7 0.4 0.11 12.8 0.2 4.2 5 1 0 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain DUF829 PF05705.14 OAP62947.1 - 0.074 12.9 0.0 0.82 9.5 0.0 2.2 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF829) Pantoate_ligase PF02569.15 OAP62948.1 - 5.8e-83 278.2 0.0 7e-83 277.9 0.0 1.1 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase DEAD PF00270.29 OAP62949.1 - 3.1e-42 144.3 0.1 4.8e-42 143.7 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.6 OAP62949.1 - 3.8e-20 71.9 0.0 8.5e-20 70.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.31 OAP62949.1 - 1.4e-19 70.5 0.0 8.9e-19 67.9 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAP62949.1 - 3.7e-06 27.1 0.1 7.4e-06 26.1 0.1 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit WD40 PF00400.32 OAP62950.1 - 5.4e-12 46.0 8.2 0.015 16.2 1.0 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAP62950.1 - 0.0006 20.0 0.0 29 5.1 0.0 4.6 3 2 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Rib_5-P_isom_A PF06026.14 OAP62951.1 - 1.6e-41 141.8 0.0 2.7e-41 141.1 0.0 1.3 1 1 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) ThiF PF00899.21 OAP62952.1 - 1.8e-14 53.7 0.0 4.3e-14 52.5 0.0 1.6 1 1 0 1 1 1 1 ThiF family LRR_4 PF12799.7 OAP62953.1 - 1.8e-36 123.6 41.1 4.8e-06 26.8 0.1 10.7 9 2 4 13 13 13 11 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OAP62953.1 - 3.8e-30 103.4 34.9 4.5e-07 29.5 0.6 9.1 7 2 1 8 8 8 7 Leucine rich repeat LRR_1 PF00560.33 OAP62953.1 - 1.9e-11 42.8 36.7 9 7.3 0.1 14.9 17 0 0 17 17 17 6 Leucine Rich Repeat LRR_6 PF13516.6 OAP62953.1 - 2.3e-09 36.6 27.2 4.2 7.7 0.1 13.2 13 1 1 14 14 14 5 Leucine Rich repeat LRR_9 PF14580.6 OAP62953.1 - 1.3e-06 28.1 13.0 0.004 16.7 0.6 4.7 2 1 2 4 4 4 3 Leucine-rich repeat Herpes_BLRF2 PF05812.12 OAP62954.1 - 0.068 13.3 5.3 0.058 13.5 1.1 2.4 1 1 2 3 3 3 0 Herpesvirus BLRF2 protein YabA PF06156.13 OAP62954.1 - 4.8 7.9 9.5 0.86 10.3 2.1 2.3 2 0 0 2 2 2 0 Initiation control protein YabA Ribosomal_L13e PF01294.18 OAP62955.1 - 4.2e-72 241.8 2.6 6.3e-72 241.2 2.6 1.3 1 0 0 1 1 1 1 Ribosomal protein L13e Tmemb_cc2 PF10267.9 OAP62956.1 - 0.0034 16.6 1.7 0.0059 15.8 1.7 1.3 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein Pex19 PF04614.12 OAP62956.1 - 0.018 14.8 4.1 0.031 14.1 4.1 1.3 1 0 0 1 1 1 0 Pex19 protein family Macoilin PF09726.9 OAP62956.1 - 0.095 11.2 0.9 0.12 10.9 0.9 1.2 1 0 0 1 1 1 0 Macoilin family DivIC PF04977.15 OAP62956.1 - 0.26 11.1 1.5 0.79 9.5 1.5 1.8 1 0 0 1 1 1 0 Septum formation initiator CDC45 PF02724.14 OAP62956.1 - 2.5 6.3 6.8 4.4 5.5 6.8 1.4 1 0 0 1 1 1 0 CDC45-like protein RRN3 PF05327.11 OAP62956.1 - 3.3 6.1 6.9 5.3 5.4 6.9 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Sigma70_ner PF04546.13 OAP62956.1 - 4 7.3 10.5 0.4 10.5 5.8 1.7 2 0 0 2 2 2 0 Sigma-70, non-essential region HIP1_clath_bdg PF16515.5 OAP62956.1 - 4.3 8.0 13.6 1.3 9.7 8.8 2.3 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Spt5_N PF11942.8 OAP62956.1 - 8.4 7.4 19.3 16 6.5 13.8 2.7 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal DUF3433 PF11915.8 OAP62957.1 - 7.5e-25 87.2 11.5 7.2e-14 52.0 3.9 4.3 5 0 0 5 5 5 2 Protein of unknown function (DUF3433) Fungal_trans_2 PF11951.8 OAP62958.1 - 4.9e-08 32.2 0.0 1.8e-06 27.1 0.0 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF4820 PF16091.5 OAP62959.1 - 0.11 11.9 4.4 0.13 11.6 4.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) MFS_1 PF07690.16 OAP62960.1 - 1.7e-25 89.7 29.0 1.7e-25 89.7 29.0 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily GPI-anchored PF10342.9 OAP62961.1 - 6.7e-20 71.7 0.0 6.7e-20 71.7 0.0 2.1 3 0 0 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family FlhE PF06366.13 OAP62961.1 - 0.042 13.8 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 Flagellar protein FlhE DUF4448 PF14610.6 OAP62961.1 - 0.05 13.4 0.0 0.46 10.2 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) PVL_ORF50 PF07768.11 OAP62962.1 - 3.8 7.9 11.5 5.6 7.3 7.8 2.1 2 0 0 2 2 2 0 PVL ORF-50-like family CLTH PF10607.9 OAP62963.1 - 7.8e-32 110.2 0.2 1.1e-31 109.7 0.2 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 OAP62963.1 - 3.3e-09 36.4 0.0 7.5e-09 35.2 0.0 1.7 1 0 0 1 1 1 1 LisH HU-HIG PF18291.1 OAP62963.1 - 0.0032 17.5 0.0 0.007 16.5 0.0 1.5 1 0 0 1 1 1 1 HU domain fused to wHTH, Ig, or Glycine-rich motif PrkA PF06798.12 OAP62963.1 - 0.073 12.7 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 PrkA serine protein kinase C-terminal domain MOZ_SAS PF01853.18 OAP62964.1 - 2.1e-76 255.6 0.0 3.2e-76 255.0 0.0 1.3 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 OAP62964.1 - 1.8e-23 81.9 0.4 3.7e-23 80.9 0.4 1.5 1 0 0 1 1 1 1 MYST family zinc finger domain Tudor-knot PF11717.8 OAP62964.1 - 3e-22 78.3 0.0 5.6e-22 77.4 0.0 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 OAP62964.1 - 0.00093 19.6 0.0 0.0019 18.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAP62964.1 - 0.0059 16.8 0.0 0.013 15.7 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family WD40 PF00400.32 OAP62965.1 - 3.6e-19 68.8 3.8 0.00021 22.0 0.0 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.8 OAP62965.1 - 2.1e-08 33.3 0.1 3e-05 22.9 0.0 3.0 2 1 1 3 3 3 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 OAP62965.1 - 5.3e-08 33.0 0.1 0.0017 18.6 0.1 4.7 3 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 OAP62965.1 - 0.0071 15.1 0.0 0.51 9.0 0.0 2.7 2 1 0 2 2 2 1 Nup133 N terminal like PQQ_3 PF13570.6 OAP62965.1 - 0.093 13.2 0.4 10 6.8 0.0 3.7 5 0 0 5 5 5 0 PQQ-like domain Cmc1 PF08583.10 OAP62966.1 - 1.3e-18 66.8 2.0 1.5e-18 66.6 2.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Flu_B_M2 PF04772.12 OAP62966.1 - 0.092 13.0 0.0 0.11 12.7 0.0 1.1 1 0 0 1 1 1 0 Influenza B matrix protein 2 (BM2) DUF726 PF05277.12 OAP62967.1 - 2.8e-127 424.4 2.5 3.8e-127 423.9 2.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Glyco_tranf_2_3 PF13641.6 OAP62968.1 - 6.7e-24 85.0 0.1 9.9e-24 84.5 0.1 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 OAP62968.1 - 4.5e-08 32.8 0.1 2.3e-07 30.4 0.1 2.1 1 1 0 1 1 1 1 Glycosyl transferase family 21 GRIP PF01465.20 OAP62969.1 - 4.9e-17 61.6 0.1 1.2e-16 60.3 0.1 1.7 1 0 0 1 1 1 1 GRIP domain YL1_C PF08265.11 OAP62969.1 - 1.5e-14 53.5 1.0 2.6e-14 52.7 1.0 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain CENP-F_leu_zip PF10473.9 OAP62969.1 - 0.00046 20.2 48.9 0.002 18.2 18.2 10.3 3 2 8 11 11 10 5 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.12 OAP62969.1 - 0.0018 18.3 4.8 0.0018 18.3 4.8 11.1 5 3 6 11 11 11 6 Protein of unknown function (DUF1664) TMF_TATA_bd PF12325.8 OAP62969.1 - 0.0033 17.6 6.9 0.0033 17.6 6.9 11.1 3 2 6 10 10 9 1 TATA element modulatory factor 1 TATA binding CALCOCO1 PF07888.11 OAP62969.1 - 0.0061 15.5 153.6 0.0046 15.9 33.1 5.9 3 1 2 5 5 5 4 Calcium binding and coiled-coil domain (CALCOCO1) like DUF5333 PF17267.2 OAP62969.1 - 0.039 14.1 0.4 0.039 14.1 0.4 4.6 5 1 0 5 5 5 0 Family of unknown function (DUF5333) GAS PF13851.6 OAP62969.1 - 0.2 11.0 161.3 0.044 13.1 14.8 10.4 4 2 4 9 9 9 0 Growth-arrest specific micro-tubule binding Nuc_N PF14448.6 OAP62969.1 - 0.45 10.4 3.3 53 3.8 0.1 4.0 3 0 0 3 3 3 0 Nuclease N terminal ATG16 PF08614.11 OAP62969.1 - 1.3 9.2 200.4 0.014 15.6 9.0 10.4 5 2 5 10 10 10 0 Autophagy protein 16 (ATG16) FPP PF05911.11 OAP62969.1 - 3.3 5.8 153.7 0.013 13.7 15.9 7.2 2 2 4 7 7 7 0 Filament-like plant protein, long coiled-coil Spc7 PF08317.11 OAP62969.1 - 5.9 5.7 162.6 0.059 12.3 11.6 7.7 3 2 3 7 7 7 0 Spc7 kinetochore protein Sulfotransfer_4 PF17784.1 OAP62970.1 - 6.5e-60 202.6 0.0 7.7e-60 202.4 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OAP62970.1 - 0.00022 21.7 0.2 0.0018 18.7 0.0 2.3 1 1 2 3 3 3 1 Sulfotransferase family NmrA PF05368.13 OAP62971.1 - 2.5e-29 102.5 0.0 3.4e-29 102.0 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAP62971.1 - 5e-10 39.6 0.0 9.6e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAP62971.1 - 4.6e-08 32.8 0.1 0.00022 20.8 0.1 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OAP62971.1 - 4.7e-06 25.8 0.6 7.9e-06 25.1 0.6 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 OAP62971.1 - 8.7e-05 23.0 0.1 0.00094 19.6 0.0 2.2 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 OAP62971.1 - 0.00018 21.8 0.5 0.00043 20.6 0.2 1.8 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain KR PF08659.10 OAP62971.1 - 0.0061 16.5 0.0 0.01 15.8 0.0 1.3 1 0 0 1 1 1 1 KR domain DapB_N PF01113.20 OAP62971.1 - 0.018 15.2 0.1 0.04 14.0 0.1 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus GDP_Man_Dehyd PF16363.5 OAP62971.1 - 0.031 13.7 0.1 0.39 10.1 0.1 2.0 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 OAP62971.1 - 0.054 12.6 0.1 0.078 12.1 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Toxin-deaminase PF14424.6 OAP62971.1 - 0.16 12.1 0.0 0.67 10.1 0.0 2.0 2 1 0 2 2 2 0 The BURPS668_1122 family of deaminases Actin PF00022.19 OAP62972.1 - 1.2e-47 162.5 0.0 6.7e-25 87.5 0.0 2.3 2 0 0 2 2 2 2 Actin bZIP_1 PF00170.21 OAP62974.1 - 1.7e-08 34.5 7.0 5.2e-08 32.9 7.0 1.7 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 OAP62974.1 - 0.17 12.0 9.7 1.6 8.9 5.6 2.2 1 1 1 2 2 2 0 Basic region leucine zipper Imm32 PF15566.6 OAP62974.1 - 0.17 11.7 0.1 1.7 8.5 0.0 2.2 2 0 0 2 2 2 0 Immunity protein 32 Peptidase_S10 PF00450.22 OAP62975.1 - 3.9e-76 257.1 0.0 5.9e-76 256.5 0.0 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase SOG2 PF10428.9 OAP62975.1 - 6.3 5.9 11.7 9.8 5.2 11.7 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein RNA_pol_A_bac PF01000.26 OAP62976.1 - 2.1e-28 98.9 0.0 3.2e-28 98.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 OAP62976.1 - 7.4e-14 50.9 0.0 9.9e-14 50.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Transketolase_N PF00456.21 OAP62977.1 - 1.3e-153 510.8 0.1 1.7e-153 510.5 0.1 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 OAP62977.1 - 2.8e-45 154.2 0.0 5.8e-45 153.1 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 OAP62977.1 - 1.6e-10 41.0 0.0 3.1e-10 40.0 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 OAP62977.1 - 2.7e-05 23.5 0.0 4.8e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Beta_elim_lyase PF01212.21 OAP62977.1 - 0.0074 15.6 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase E1_dh PF00676.20 OAP62977.1 - 0.0088 15.0 0.1 0.013 14.4 0.1 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component GtrA PF04138.14 OAP62977.1 - 0.037 14.3 0.0 0.078 13.2 0.0 1.5 1 0 0 1 1 1 0 GtrA-like protein PFO_beta_C PF12367.8 OAP62977.1 - 0.12 12.5 0.0 0.48 10.6 0.0 2.0 1 0 0 1 1 1 0 Pyruvate ferredoxin oxidoreductase beta subunit C terminal zf-RING_13 PF17977.1 OAP62977.1 - 0.14 12.3 0.8 0.42 10.8 0.2 2.1 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain adh_short PF00106.25 OAP62978.1 - 6.9e-30 104.0 0.0 9e-30 103.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP62978.1 - 6.1e-20 71.8 0.0 1.9e-19 70.1 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP62978.1 - 8.9e-07 29.0 0.2 2.7e-06 27.4 0.1 1.7 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 OAP62978.1 - 1.2e-05 25.0 0.0 0.00081 18.9 0.0 2.3 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 OAP62978.1 - 2.8e-05 24.1 0.1 6.6e-05 22.9 0.1 1.8 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 OAP62978.1 - 0.019 14.5 0.1 0.035 13.6 0.1 1.4 1 0 0 1 1 1 0 NmrA-like family GDP_Man_Dehyd PF16363.5 OAP62978.1 - 0.062 12.7 0.0 0.12 11.7 0.0 1.5 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 OAP62978.1 - 0.098 11.6 0.0 0.18 10.8 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family RRM_1 PF00076.22 OAP62979.1 - 4.7e-83 273.0 3.6 2e-21 75.6 0.4 5.3 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 OAP62979.1 - 8.8e-31 105.9 0.5 4.3e-30 103.7 0.4 2.3 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 OAP62979.1 - 4.7e-15 55.3 0.3 0.0096 15.5 0.0 5.3 2 1 3 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OAP62979.1 - 3e-06 27.0 0.1 0.00055 19.8 0.0 3.4 4 0 0 4 4 4 1 Occluded RNA-recognition motif Limkain-b1 PF11608.8 OAP62979.1 - 8.7e-06 25.7 1.8 0.59 10.2 0.1 4.4 4 0 0 4 4 4 2 Limkain b1 RRM_7 PF16367.5 OAP62979.1 - 5.1e-05 23.3 0.1 2.3 8.4 0.0 5.0 5 1 0 5 5 5 1 RNA recognition motif Nup35_RRM_2 PF14605.6 OAP62979.1 - 7.2e-05 22.7 0.3 5.8 7.0 0.0 4.2 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif YflT PF11181.8 OAP62979.1 - 0.0011 19.4 7.3 0.011 16.3 0.7 2.9 3 0 0 3 3 3 1 Heat induced stress protein YflT OB_RNB PF08206.11 OAP62979.1 - 0.049 13.3 1.1 17 5.1 0.0 3.5 3 0 0 3 3 3 0 Ribonuclease B OB domain PhetRS_B1 PF18262.1 OAP62979.1 - 0.084 13.1 0.3 8.4 6.7 0.0 3.1 3 0 0 3 3 3 0 Phe-tRNA synthetase beta subunit B1 domain Spore_coat_CotO PF14153.6 OAP62979.1 - 8.4 6.3 10.0 22 4.9 10.0 1.8 1 1 0 1 1 1 0 Spore coat protein CotO Mpv17_PMP22 PF04117.12 OAP62982.1 - 2.6e-13 50.0 4.8 4.8e-13 49.1 2.0 2.2 2 0 0 2 2 2 1 Mpv17 / PMP22 family PseudoU_synth_1 PF01416.20 OAP62982.1 - 0.091 13.2 0.0 0.9 10.0 0.0 2.1 2 0 0 2 2 2 0 tRNA pseudouridine synthase Cullin PF00888.22 OAP62983.1 - 6e-171 570.2 2.1 7.8e-171 569.8 2.1 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 OAP62983.1 - 2.7e-23 81.8 1.9 5.6e-23 80.8 1.9 1.6 1 0 0 1 1 1 1 Cullin protein neddylation domain EF-hand_7 PF13499.6 OAP62983.1 - 0.054 14.0 2.4 7.6 7.1 0.1 3.8 4 0 0 4 4 4 0 EF-hand domain pair Rep_fac-A_3 PF08661.11 OAP62984.1 - 9.6e-19 67.7 0.0 1.1e-18 67.4 0.0 1.1 1 0 0 1 1 1 1 Replication factor A protein 3 GATA PF00320.27 OAP62985.1 - 1.7e-06 27.5 4.4 0.011 15.4 0.1 3.5 3 0 0 3 3 3 2 GATA zinc finger Dak1 PF02733.17 OAP62986.1 - 1e-102 343.2 0.6 1.9e-102 342.4 0.6 1.4 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 OAP62986.1 - 1.4e-49 168.3 1.6 3.4e-49 167.1 1.6 1.7 1 0 0 1 1 1 1 DAK2 domain RIO1 PF01163.22 OAP62987.1 - 3.3e-45 154.0 0.0 5.2e-45 153.4 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.11 OAP62987.1 - 5.3e-29 100.3 0.0 1.1e-28 99.3 0.0 1.5 1 0 0 1 1 1 1 Rio2, N-terminal Kdo PF06293.14 OAP62987.1 - 4.6e-08 32.7 0.0 0.0056 16.0 0.0 2.2 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OAP62987.1 - 6.3e-08 32.8 0.7 0.0018 18.2 0.1 2.7 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 OAP62987.1 - 0.13 11.5 0.1 5.3 6.3 0.0 2.3 2 0 0 2 2 2 0 Kinase-like Kinesin PF00225.23 OAP62988.1 - 3.7e-93 312.1 1.6 5.6e-93 311.5 0.0 2.2 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 OAP62988.1 - 6.1e-22 78.2 0.0 7.3e-18 64.9 0.0 3.6 2 1 1 3 3 3 2 Microtubule binding DUF4201 PF13870.6 OAP62988.1 - 0.0011 18.8 6.3 0.0011 18.8 6.3 10.8 10 1 1 11 11 11 3 Domain of unknown function (DUF4201) zf-C4H2 PF10146.9 OAP62988.1 - 0.0013 19.1 5.3 0.0013 19.1 5.3 8.5 4 1 3 7 7 7 1 Zinc finger-containing protein Filament PF00038.21 OAP62988.1 - 0.0014 18.3 26.2 0.0014 18.3 26.2 8.3 3 2 2 6 6 6 2 Intermediate filament protein Cir_Bir_Yir PF06022.11 OAP62988.1 - 0.23 10.9 4.2 0.13 11.7 0.8 2.3 2 0 0 2 2 2 0 Plasmodium variant antigen protein Cir/Yir/Bir S-AdoMet_synt_C PF02773.16 OAP62989.1 - 6.4e-67 223.8 0.1 3e-66 221.6 0.0 1.9 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 OAP62989.1 - 8e-47 158.4 0.0 1.4e-46 157.6 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 OAP62989.1 - 6.2e-44 148.7 0.5 1.1e-43 147.9 0.1 1.6 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain AdoMet_Synthase PF01941.19 OAP62989.1 - 0.15 10.8 0.2 0.8 8.4 0.1 1.9 1 1 1 2 2 2 0 S-adenosylmethionine synthetase (AdoMet synthetase) ATP_bind_1 PF03029.17 OAP62990.1 - 4.2e-74 249.4 0.0 3.1e-73 246.5 0.0 1.9 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein CLP1_P PF16575.5 OAP62990.1 - 0.00032 20.6 0.0 0.00068 19.5 0.0 1.5 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_14 PF13173.6 OAP62990.1 - 0.00049 20.1 0.0 0.0013 18.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 OAP62990.1 - 0.00054 20.5 0.0 0.0014 19.1 0.0 1.8 2 0 0 2 2 1 1 AAA domain DUF463 PF04317.12 OAP62990.1 - 0.00082 18.4 0.0 0.0013 17.8 0.0 1.2 1 0 0 1 1 1 1 YcjX-like family, DUF463 AAA_16 PF13191.6 OAP62990.1 - 0.0014 19.0 0.0 0.006 17.0 0.0 1.8 2 1 0 2 2 1 1 AAA ATPase domain cobW PF02492.19 OAP62990.1 - 0.0023 17.5 0.1 0.097 12.3 0.0 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 OAP62990.1 - 0.0028 17.9 0.0 0.0069 16.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 OAP62990.1 - 0.0033 16.5 0.0 0.0048 16.0 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_24 PF13479.6 OAP62990.1 - 0.0035 17.1 0.0 0.0058 16.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OAP62990.1 - 0.0048 17.2 0.7 0.1 12.9 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 OAP62990.1 - 0.0063 16.3 0.0 0.025 14.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain CbiA PF01656.23 OAP62990.1 - 0.012 15.7 0.0 0.016 15.3 0.0 1.3 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_29 PF13555.6 OAP62990.1 - 0.013 15.2 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.22 OAP62990.1 - 0.015 15.7 0.0 0.033 14.6 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA PF00004.29 OAP62990.1 - 0.015 15.7 0.0 0.03 14.7 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 OAP62990.1 - 0.016 15.1 0.0 0.028 14.3 0.0 1.3 1 0 0 1 1 1 0 NTPase ArsA_ATPase PF02374.15 OAP62990.1 - 0.018 14.2 0.0 0.034 13.3 0.0 1.4 1 0 0 1 1 1 0 Anion-transporting ATPase AAA_33 PF13671.6 OAP62990.1 - 0.019 15.1 0.0 0.032 14.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 OAP62990.1 - 0.022 14.8 0.0 0.036 14.1 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 OAP62990.1 - 0.026 14.4 0.0 0.045 13.7 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_7 PF12775.7 OAP62990.1 - 0.036 13.6 0.0 0.074 12.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase_2 PF01637.18 OAP62990.1 - 0.058 13.3 0.0 0.13 12.1 0.0 1.6 2 0 0 2 2 1 0 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 OAP62990.1 - 0.058 13.1 0.0 0.088 12.5 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain APS_kinase PF01583.20 OAP62990.1 - 0.065 13.1 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase SRP54 PF00448.22 OAP62990.1 - 0.076 12.6 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ATPase PF06745.13 OAP62990.1 - 0.1 11.9 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 KaiC IstB_IS21 PF01695.17 OAP62990.1 - 0.13 12.0 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein GTP_EFTU PF00009.27 OAP62990.1 - 0.16 11.5 0.1 12 5.4 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain KAP_NTPase PF07693.14 OAP62990.1 - 0.19 10.9 0.0 0.19 10.9 0.0 1.3 1 1 0 1 1 1 0 KAP family P-loop domain ResIII PF04851.15 OAP62990.1 - 0.26 11.3 0.0 0.43 10.6 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DUF2075 PF09848.9 OAP62990.1 - 0.28 10.4 0.0 0.37 10.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Apq12 PF12716.7 OAP62991.1 - 5.8e-13 48.6 6.8 9.2e-13 47.9 6.8 1.3 1 0 0 1 1 1 1 Nuclear pore assembly and biogenesis Auxin_canalis PF05703.11 OAP62991.1 - 0.042 13.8 0.5 0.062 13.2 0.5 1.1 1 0 0 1 1 1 0 Auxin canalisation DUF5336 PF17270.2 OAP62991.1 - 1 9.0 5.6 1.6 8.4 5.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5336) PKcGMP_CC PF16808.5 OAP62992.1 - 6.4 6.7 13.7 21 5.1 0.4 5.5 5 0 0 5 5 5 0 Coiled-coil N-terminus of cGMP-dependent protein kinase V-ATPase_H_N PF03224.14 OAP62993.1 - 2.9e-81 273.2 0.1 3.9e-81 272.8 0.1 1.2 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 OAP62993.1 - 4e-37 126.9 0.0 1.3e-36 125.2 0.0 2.0 1 0 0 1 1 1 1 V-ATPase subunit H NAT PF04768.13 OAP62993.1 - 0.051 13.2 0.0 7.9 6.1 0.0 2.4 2 0 0 2 2 2 0 NAT, N-acetyltransferase, of N-acetylglutamate synthase HEAT PF02985.22 OAP62993.1 - 0.094 13.0 0.0 0.6 10.5 0.0 2.4 2 0 0 2 2 2 0 HEAT repeat TMF_TATA_bd PF12325.8 OAP62994.1 - 2.4e-40 137.3 13.3 2.4e-40 137.3 13.3 7.6 3 1 6 9 9 9 1 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.8 OAP62994.1 - 4.2e-11 42.7 7.9 4.2e-11 42.7 7.9 9.8 7 2 2 9 9 9 2 TATA element modulatory factor 1 DNA binding ATG16 PF08614.11 OAP62994.1 - 5.4e-05 23.5 6.5 5.4e-05 23.5 6.5 5.8 2 1 4 6 6 6 1 Autophagy protein 16 (ATG16) TPR_MLP1_2 PF07926.12 OAP62994.1 - 0.012 15.7 24.4 0.012 15.7 24.4 6.4 3 1 3 6 6 6 0 TPR/MLP1/MLP2-like protein Ank_2 PF12796.7 OAP62995.1 - 1.2e-35 122.0 1.0 7.7e-11 42.4 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAP62995.1 - 5e-34 116.2 9.1 4e-10 40.0 0.0 5.5 2 1 4 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 OAP62995.1 - 3.1e-32 110.2 2.1 1.7e-10 40.9 0.0 5.3 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAP62995.1 - 1.9e-29 98.4 0.7 9.2e-05 22.6 0.0 6.2 6 0 0 6 6 6 6 Ankyrin repeat Ank PF00023.30 OAP62995.1 - 9e-27 92.3 8.4 1.4e-05 25.3 0.0 6.1 6 0 0 6 6 6 6 Ankyrin repeat Shal-type PF11601.8 OAP62995.1 - 0.11 12.0 2.2 0.7 9.5 0.0 2.3 2 0 0 2 2 2 0 Shal-type voltage-gated potassium channels, N-terminal Fungal_trans PF04082.18 OAP62996.1 - 9.8e-12 44.4 0.1 1.8e-11 43.6 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain K_trans PF02705.16 OAP62997.1 - 4.6e-180 599.7 16.5 4.6e-180 599.7 16.5 1.9 2 0 0 2 2 2 1 K+ potassium transporter GAGA_bind PF06217.12 OAP62997.1 - 0.005 17.2 16.2 0.0083 16.4 16.2 1.3 1 0 0 1 1 1 1 GAGA binding protein-like family DUF4776 PF16003.5 OAP62997.1 - 0.01 14.8 17.8 0.015 14.4 17.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) SRP-alpha_N PF04086.13 OAP62997.1 - 0.011 15.6 18.6 0.019 14.9 18.6 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF2828 PF11443.8 OAP62997.1 - 0.09 10.9 16.9 0.13 10.3 16.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Neur_chan_memb PF02932.16 OAP62997.1 - 0.24 11.5 5.2 0.59 10.1 5.2 1.8 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Mur_ligase_M PF08245.12 OAP62997.1 - 0.34 10.9 4.8 0.71 9.8 4.8 1.5 1 0 0 1 1 1 0 Mur ligase middle domain SpoIIP PF07454.11 OAP62997.1 - 0.39 10.1 14.4 0.72 9.3 14.4 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) RR_TM4-6 PF06459.12 OAP62997.1 - 0.58 9.9 18.9 1.2 9.0 18.9 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DAG_kinase_N PF14513.6 OAP62997.1 - 1.4 9.1 11.9 3.2 7.9 11.9 1.5 1 0 0 1 1 1 0 Diacylglycerol kinase N-terminus PcfK PF14058.6 OAP62997.1 - 2.4 8.4 28.1 1.7 9.0 26.1 1.7 2 0 0 2 2 2 0 PcfK-like protein Connexin PF00029.19 OAP62997.1 - 2.5 7.8 18.3 7.8 6.2 18.3 1.8 1 0 0 1 1 1 0 Connexin RNA_pol_Rpc4 PF05132.14 OAP62997.1 - 2.6 8.5 19.1 1.2 9.6 15.7 2.0 2 0 0 2 2 2 0 RNA polymerase III RPC4 DUF4064 PF13273.6 OAP62997.1 - 2.8 8.2 14.0 0.72 10.2 5.7 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) DUF4228 PF14009.6 OAP62997.1 - 3.1 8.2 9.4 6.1 7.2 9.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) EIIBC-GUT_N PF03612.14 OAP62997.1 - 3.9 7.2 13.7 8.4 6.1 13.7 1.5 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus LicD PF04991.13 OAP62997.1 - 4 7.5 17.9 7 6.7 17.9 1.3 1 0 0 1 1 1 0 LicD family MMU163 PF17119.5 OAP62997.1 - 4.1 6.5 11.6 7.5 5.6 11.6 1.3 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis Band_3_cyto PF07565.13 OAP62997.1 - 5.1 6.8 9.8 8.8 6.0 9.8 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain NARP1 PF12569.8 OAP62997.1 - 6.1 5.6 32.3 9.9 4.9 32.3 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Peptidase_U57 PF05582.12 OAP62997.1 - 8.3 5.6 14.2 16 4.7 14.2 1.4 1 0 0 1 1 1 0 YabG peptidase U57 GCD14 PF08704.10 OAP62997.1 - 9.9 5.8 9.0 16 5.1 9.0 1.3 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit zf-RING_2 PF13639.6 OAP62998.1 - 3.8e-12 46.3 5.8 6.8e-12 45.5 5.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 OAP62998.1 - 5.3e-09 35.7 2.6 5.3e-09 35.7 2.6 2.2 2 0 0 2 2 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 OAP62998.1 - 8.6e-08 31.9 4.9 1.5e-07 31.1 4.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAP62998.1 - 1.6e-06 27.9 2.5 2.5e-06 27.3 2.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAP62998.1 - 1e-05 25.4 3.0 1.5e-05 24.8 3.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 OAP62998.1 - 2.8e-05 23.9 3.1 4.5e-05 23.2 3.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OAP62998.1 - 0.00011 22.4 10.1 0.00023 21.4 7.6 2.5 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 OAP62998.1 - 0.00019 21.4 2.6 0.00023 21.1 1.0 2.0 1 1 1 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 OAP62998.1 - 0.0013 18.6 5.1 0.0023 17.8 5.1 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 OAP62998.1 - 0.0054 16.3 3.9 0.0088 15.6 3.9 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 OAP62998.1 - 0.0064 16.5 2.2 0.015 15.3 2.2 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_1 PF14446.6 OAP62998.1 - 0.012 15.5 3.4 0.046 13.7 1.0 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 YdjO PF14169.6 OAP62998.1 - 0.042 13.6 0.3 8.4 6.2 0.1 2.6 2 0 0 2 2 2 0 Cold-inducible protein YdjO Baculo_IE-1 PF05290.11 OAP62998.1 - 0.1 12.5 0.7 0.18 11.8 0.7 1.3 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-C3HC4_4 PF15227.6 OAP62998.1 - 0.14 12.3 2.4 0.33 11.1 2.4 1.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING MafB19-deam PF14437.6 OAP62998.1 - 0.18 11.6 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 MafB19-like deaminase zf-RING_4 PF14570.6 OAP62998.1 - 0.23 11.3 3.6 0.36 10.7 3.6 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING-like PF08746.11 OAP62998.1 - 0.53 10.6 3.6 0.91 9.9 3.6 1.4 1 0 0 1 1 1 0 RING-like domain VPR PF00522.18 OAP63000.1 - 0.15 12.1 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 VPR/VPX protein DED PF01335.21 OAP63000.1 - 0.15 12.4 0.1 26 5.2 0.2 2.3 1 1 1 2 2 2 0 Death effector domain Asp_protease_2 PF13650.6 OAP63005.1 - 0.0013 19.3 0.0 0.0029 18.2 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 OAP63005.1 - 0.0018 18.8 0.0 0.0051 17.3 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 OAP63005.1 - 0.03 14.6 0.0 0.058 13.7 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease PF09668.10 OAP63005.1 - 0.067 13.0 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease eIF3_subunit PF08597.10 OAP63006.1 - 0.87 9.5 14.4 1.1 9.2 14.4 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit WD40 PF00400.32 OAP63007.1 - 4.1e-44 147.7 15.4 8.6e-09 35.9 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAP63007.1 - 3.3e-05 24.1 0.4 7.2 7.0 0.0 4.9 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OAP63007.1 - 0.0024 16.6 1.2 10 4.6 0.0 3.9 1 1 3 4 4 4 3 Nucleoporin Nup120/160 GDPD_2 PF13653.6 OAP63009.1 - 0.069 13.6 0.3 0.21 12.1 0.2 2.0 2 0 0 2 2 2 0 Glycerophosphoryl diester phosphodiesterase family ADH_N PF08240.12 OAP63011.1 - 3.9e-28 97.5 0.4 7.4e-28 96.6 0.4 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_assoc PF13823.6 OAP63011.1 - 3.5e-10 39.6 0.3 8.8e-10 38.3 0.3 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated ADH_zinc_N PF00107.26 OAP63011.1 - 3.7e-08 33.4 0.7 8.9e-08 32.2 0.7 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 OAP63011.1 - 3.9e-05 23.2 0.0 0.00032 20.3 0.0 2.1 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 OAP63011.1 - 0.0048 16.2 0.1 0.0089 15.3 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 OAP63011.1 - 0.006 15.3 0.3 0.016 13.9 0.1 1.7 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 OAP63011.1 - 0.028 13.5 0.6 0.038 13.1 0.6 1.2 1 0 0 1 1 1 0 FAD binding domain TrkA_N PF02254.18 OAP63011.1 - 0.092 13.0 0.1 0.16 12.2 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox PF00070.27 OAP63011.1 - 0.093 13.3 0.1 0.35 11.5 0.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_25 PF13649.6 OAP63011.1 - 0.11 13.2 0.0 0.23 12.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Arm PF00514.23 OAP63012.1 - 1.1e-94 307.9 13.1 6.8e-14 51.4 0.0 8.4 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat IBB PF01749.20 OAP63012.1 - 6.1e-27 93.9 3.2 1.5e-26 92.7 3.2 1.7 1 0 0 1 1 1 1 Importin beta binding domain Arm_3 PF16186.5 OAP63012.1 - 4.9e-24 83.7 3.9 1.6e-23 82.0 3.2 2.1 2 0 0 2 2 2 1 Atypical Arm repeat HEAT_EZ PF13513.6 OAP63012.1 - 5.3e-20 71.5 5.0 1.4e-09 38.2 0.1 6.0 3 2 3 6 6 6 4 HEAT-like repeat HEAT_2 PF13646.6 OAP63012.1 - 2.1e-18 66.5 3.9 2.4e-09 37.5 0.1 5.3 2 1 3 6 6 5 3 HEAT repeats HEAT PF02985.22 OAP63012.1 - 3.1e-18 64.3 0.3 3.5e-06 26.8 0.0 6.6 7 0 0 7 7 7 4 HEAT repeat Arm_2 PF04826.13 OAP63012.1 - 3.8e-09 36.4 0.0 0.0014 18.1 0.0 3.8 2 1 2 4 4 4 2 Armadillo-like Adaptin_N PF01602.20 OAP63012.1 - 4.7e-06 25.5 0.0 0.00063 18.4 0.0 2.4 1 1 1 2 2 2 2 Adaptin N terminal region V-ATPase_H_C PF11698.8 OAP63012.1 - 5.6e-05 23.2 0.0 0.97 9.6 0.0 4.5 3 2 1 4 4 4 2 V-ATPase subunit H HEAT_PBS PF03130.16 OAP63012.1 - 0.00059 20.3 1.0 0.8 10.6 0.1 4.4 4 0 0 4 4 4 1 PBS lyase HEAT-like repeat Cnd1 PF12717.7 OAP63012.1 - 0.00088 19.3 0.0 2.7 8.0 0.0 3.3 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Gcn1_N PF12074.8 OAP63012.1 - 0.031 13.6 0.1 7.3 5.8 0.0 2.5 2 1 0 2 2 2 0 Generalcontrol nonderepressible 1 (Gcn1) N-terminal RICTOR_V PF14668.6 OAP63012.1 - 0.049 13.9 4.6 1.1 9.5 0.0 4.4 3 2 2 5 5 5 0 Rapamycin-insensitive companion of mTOR, domain 5 Glycos_trans_3N PF02885.17 OAP63012.1 - 0.17 11.7 0.0 43 4.0 0.0 3.5 3 0 0 3 3 3 0 Glycosyl transferase family, helical bundle domain POT1PC PF16686.5 OAP63013.1 - 2.9e-34 118.2 0.1 8.2e-34 116.7 0.0 1.8 2 0 0 2 2 2 1 ssDNA-binding domain of telomere protection protein POT1 PF02765.17 OAP63013.1 - 6.3e-08 32.6 0.0 1.8e-07 31.1 0.0 1.7 2 0 0 2 2 2 1 Telomeric single stranded DNA binding POT1/CDC13 TMEM214 PF10151.9 OAP63013.1 - 0.67 8.3 5.9 0.93 7.9 5.9 1.1 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator Fungal_trans PF04082.18 OAP63014.1 - 1.5e-23 83.2 0.0 2.4e-23 82.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 OAP63014.1 - 1.7e-07 31.3 12.5 0.00042 20.6 1.8 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OAP63014.1 - 9.9e-06 25.8 6.6 9.9e-06 25.8 6.6 3.0 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 OAP63014.1 - 0.00049 20.7 12.6 0.047 14.5 1.9 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger Nha1_C PF08619.10 OAP63015.1 - 1e-82 278.8 54.0 1.7e-82 278.1 53.0 1.8 1 1 0 1 1 1 1 Alkali metal cation/H+ antiporter Nha1 C terminus Na_H_Exchanger PF00999.21 OAP63015.1 - 6.6e-73 245.7 24.2 7.9e-73 245.4 24.2 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family FlgD_ig PF13860.6 OAP63015.1 - 0.024 14.5 0.2 9.6 6.2 0.0 2.5 2 0 0 2 2 2 0 FlgD Ig-like domain YrhC PF14143.6 OAP63015.1 - 0.03 14.4 0.3 0.03 14.4 0.3 2.6 3 0 0 3 3 3 0 YrhC-like protein DUF21 PF01595.20 OAP63015.1 - 0.7 9.6 7.8 0.49 10.1 4.3 2.3 2 0 0 2 2 2 0 Cyclin M transmembrane N-terminal domain Npa1 PF11707.8 OAP63016.1 - 5.2e-71 239.8 0.0 1.7e-70 238.1 0.0 2.0 1 0 0 1 1 1 1 Ribosome 60S biogenesis N-terminal NopRA1 PF16201.5 OAP63016.1 - 3.7e-44 150.7 2.4 1.8e-43 148.5 0.0 3.4 6 0 0 6 6 6 1 Nucleolar pre-ribosomal-associated protein 1 Creb_binding PF09030.10 OAP63016.1 - 0.08 13.6 0.1 26 5.6 0.0 3.4 3 0 0 3 3 3 0 Creb binding Lipid_DES PF08557.10 OAP63016.1 - 0.16 11.5 0.0 0.35 10.4 0.0 1.6 1 0 0 1 1 1 0 Sphingolipid Delta4-desaturase (DES) Pyr_redox_2 PF07992.14 OAP63017.1 - 3.8e-40 138.0 0.0 5.2e-40 137.5 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAP63017.1 - 3.2e-12 46.8 0.0 3.8e-10 40.2 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.32 OAP63017.1 - 1.9e-06 27.0 0.2 1.1e-05 24.7 0.3 2.2 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 OAP63017.1 - 0.00025 20.7 0.3 0.00089 19.0 0.3 2.0 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 OAP63017.1 - 0.0014 19.0 0.1 0.0035 17.8 0.1 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 OAP63017.1 - 0.0086 15.5 0.2 0.02 14.4 0.2 1.7 1 0 0 1 1 1 1 EF hand Nipped-B_C PF12830.7 OAP63018.1 - 9.3e-33 113.8 1.3 9.3e-33 113.8 1.3 3.4 3 0 0 3 3 3 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 OAP63018.1 - 7.6e-06 26.1 0.5 5.3e-05 23.4 0.3 2.7 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion Cnd1 PF12717.7 OAP63018.1 - 1.2e-05 25.4 0.4 0.00017 21.7 0.2 3.2 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 OAP63018.1 - 0.0028 16.3 7.8 0.0072 14.9 0.3 4.0 4 1 0 4 4 4 1 Adaptin N terminal region EnY2 PF10163.9 OAP63018.1 - 0.034 14.5 0.0 0.17 12.3 0.0 2.2 1 0 0 1 1 1 0 Transcription factor e(y)2 HEAT PF02985.22 OAP63018.1 - 0.12 12.8 6.2 2.5 8.6 0.1 5.6 5 0 0 5 5 5 0 HEAT repeat TFIIS_C PF01096.18 OAP63019.1 - 5.1e-13 48.6 2.7 5.1e-13 48.6 2.7 2.7 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) UCH_1 PF13423.6 OAP63019.1 - 0.014 15.0 0.4 0.017 14.7 0.4 1.1 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Haem_bd PF14376.6 OAP63019.1 - 0.038 13.9 0.1 0.038 13.9 0.1 1.5 1 1 0 1 1 1 0 Haem-binding domain zf_UBZ PF18439.1 OAP63019.1 - 0.067 12.8 6.3 0.51 10.0 0.0 3.5 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger RNA_POL_M_15KD PF02150.16 OAP63019.1 - 0.15 12.0 0.5 0.15 12.0 0.5 2.6 3 0 0 3 3 3 0 RNA polymerases M/15 Kd subunit Fer4_21 PF14697.6 OAP63019.1 - 0.17 12.0 7.2 0.85 9.8 0.2 2.4 2 1 0 3 3 3 0 4Fe-4S dicluster domain Cytochrome_C7 PF14522.6 OAP63019.1 - 0.35 10.9 7.0 0.061 13.3 2.8 2.0 2 1 0 2 2 2 0 Cytochrome c7 and related cytochrome c zf-RING_7 PF02591.15 OAP63019.1 - 0.54 10.5 7.0 26 5.1 0.0 3.8 4 0 0 4 4 4 0 C4-type zinc ribbon domain DZR PF12773.7 OAP63019.1 - 0.63 10.1 8.6 5.8 7.0 5.8 2.4 1 1 0 1 1 1 0 Double zinc ribbon Cytochrom_c3_2 PF14537.6 OAP63019.1 - 3.3 8.2 8.1 1.1 9.8 4.2 2.1 2 1 0 2 2 2 0 Cytochrome c3 HEAT_2 PF13646.6 OAP63020.1 - 7.1e-27 93.6 6.0 3.4e-13 49.8 0.1 3.5 2 2 2 4 4 4 2 HEAT repeats HEAT_PBS PF03130.16 OAP63020.1 - 1.2e-19 68.9 2.8 0.05 14.3 0.0 6.5 6 0 0 6 6 6 5 PBS lyase HEAT-like repeat HEAT PF02985.22 OAP63020.1 - 2.4e-06 27.3 8.1 2.9 8.4 0.0 6.6 8 0 0 8 8 8 2 HEAT repeat HEAT_EZ PF13513.6 OAP63020.1 - 1.3e-05 25.6 10.1 0.19 12.3 0.0 5.4 4 1 2 6 6 6 2 HEAT-like repeat Arm PF00514.23 OAP63020.1 - 0.002 18.1 1.9 0.97 9.6 0.0 3.3 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat DIM1 PF02966.16 OAP63021.1 - 3.4e-69 230.7 0.2 3.9e-69 230.6 0.2 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 OAP63021.1 - 0.0017 18.3 0.0 0.0021 18.0 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 OAP63021.1 - 0.019 15.3 0.6 0.038 14.3 0.6 1.6 1 1 0 1 1 1 0 Thioredoxin-like PIG-L PF02585.17 OAP63022.1 - 1.2e-23 84.2 0.0 2.2e-23 83.3 0.0 1.4 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase ATP13 PF12921.7 OAP63023.1 - 2.6e-22 78.8 0.0 5.4e-22 77.8 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial ATPase expression PPR_3 PF13812.6 OAP63023.1 - 3.2e-07 30.3 0.0 0.00016 21.7 0.0 2.7 2 0 0 2 2 2 2 Pentatricopeptide repeat domain LSM PF01423.22 OAP63024.1 - 2.3e-19 68.8 0.1 3.3e-19 68.3 0.1 1.3 1 0 0 1 1 1 1 LSM domain AalphaY_MDB PF04611.12 OAP63024.1 - 0.14 12.2 0.0 0.16 12.0 0.0 1.1 1 0 0 1 1 1 0 Mating type protein A alpha Y mating type dependent binding region GTP_EFTU PF00009.27 OAP63025.1 - 4.5e-19 68.8 0.0 9.1e-19 67.8 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 OAP63025.1 - 1.4e-08 35.0 1.2 2.3e-07 31.1 0.4 3.0 3 0 0 3 3 3 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.17 OAP63025.1 - 1.6e-05 25.2 0.0 4.1e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 OAP63025.1 - 0.01 15.9 0.1 0.045 13.8 0.0 2.1 2 1 0 2 2 2 0 50S ribosome-binding GTPase PduV-EutP PF10662.9 OAP63025.1 - 0.041 13.6 0.1 1.8 8.3 0.0 2.9 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 OAP63025.1 - 0.044 13.7 0.6 4.9 7.0 0.0 2.5 2 0 0 2 2 2 0 RsgA GTPase Roc PF08477.13 OAP63025.1 - 0.12 12.6 0.1 1.7 8.9 0.1 2.7 2 1 1 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase EamA PF00892.20 OAP63026.1 - 8.7e-06 25.9 17.2 2.4e-05 24.5 17.2 1.6 1 1 0 1 1 1 1 EamA-like transporter family TMEM234 PF10639.9 OAP63026.1 - 0.0015 18.5 4.3 0.0028 17.7 4.3 1.5 1 1 0 1 1 1 1 Putative transmembrane family 234 DUF4452 PF14618.6 OAP63027.1 - 1e-75 253.3 13.7 1.4e-75 252.9 13.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4452) Het-C PF07217.11 OAP63028.1 - 6.6e-262 870.0 0.0 4.1e-174 580.2 0.0 2.0 2 0 0 2 2 2 2 Heterokaryon incompatibility protein Het-C ECH_1 PF00378.20 OAP63029.1 - 1.6e-41 142.3 0.0 5e-41 140.7 0.0 1.6 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAP63029.1 - 1.4e-18 67.5 0.0 5e-18 65.7 0.0 1.8 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 OAP63029.1 - 0.072 13.0 0.0 3.3 7.6 0.0 2.3 2 0 0 2 2 2 0 Peptidase family S49 RSN1_7TM PF02714.15 OAP63030.1 - 2.5e-82 276.3 27.3 3.9e-82 275.7 27.3 1.3 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 OAP63030.1 - 7.5e-43 146.0 6.0 1.5e-42 145.0 0.2 3.0 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 OAP63030.1 - 5.1e-29 101.7 0.4 1.7e-16 60.9 0.0 2.6 2 0 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 OAP63030.1 - 3e-13 49.8 0.0 8.8e-13 48.2 0.0 1.8 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter MbeB_N PF04837.12 OAP63030.1 - 0.12 12.6 1.5 0.32 11.3 1.5 1.7 1 0 0 1 1 1 0 MbeB-like, N-term conserved region Vps62 PF06101.11 OAP63031.1 - 1.2e-16 60.2 1.7 5.5e-16 58.0 0.5 2.4 2 1 0 2 2 2 1 Vacuolar protein sorting-associated protein 62 Sec2p PF06428.11 OAP63032.1 - 1.2e-11 44.4 9.0 1.2e-11 44.4 9.0 2.2 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p ATG16 PF08614.11 OAP63032.1 - 0.00015 22.1 15.7 0.019 15.2 5.0 2.3 2 0 0 2 2 2 2 Autophagy protein 16 (ATG16) LMBR1 PF04791.16 OAP63032.1 - 0.0024 16.9 0.7 0.0035 16.3 0.7 1.3 1 0 0 1 1 1 1 LMBR1-like membrane protein CCDC53 PF10152.9 OAP63032.1 - 0.012 16.0 1.3 0.012 16.0 1.3 2.2 2 1 0 2 2 2 0 Subunit CCDC53 of WASH complex BRI3BP PF14965.6 OAP63032.1 - 0.024 14.1 0.4 1.5 8.3 0.0 2.3 2 0 0 2 2 2 0 Negative regulator of p53/TP53 bZIP_1 PF00170.21 OAP63032.1 - 0.047 13.8 8.3 0.58 10.3 2.3 3.0 2 1 1 3 3 3 0 bZIP transcription factor Exonuc_VII_L PF02601.15 OAP63032.1 - 0.058 13.0 7.9 0.21 11.1 4.1 2.0 2 0 0 2 2 2 0 Exonuclease VII, large subunit DUF2072 PF09845.9 OAP63032.1 - 0.088 13.1 3.7 1.7 8.9 0.0 2.3 2 0 0 2 2 2 0 Zn-ribbon containing protein zf_C2H2_10 PF18414.1 OAP63032.1 - 0.1 12.1 0.6 0.17 11.4 0.6 1.3 1 0 0 1 1 1 0 C2H2 type zinc-finger HAUS6_N PF14661.6 OAP63032.1 - 0.13 11.8 8.2 1.5 8.3 4.1 2.1 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus Jnk-SapK_ap_N PF09744.9 OAP63032.1 - 0.14 12.4 20.9 0.78 9.9 10.4 2.2 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 DUF4795 PF16043.5 OAP63032.1 - 0.83 9.2 9.0 4 7.0 2.7 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4795) Adaptin_binding PF10199.9 OAP63032.1 - 1.1 9.9 5.8 2.6 8.6 1.3 2.3 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 Atg14 PF10186.9 OAP63032.1 - 1.2 8.2 16.9 0.8 8.7 1.0 2.1 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 ADIP PF11559.8 OAP63032.1 - 1.5 8.9 18.5 1.4 9.0 1.0 2.5 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding YlqD PF11068.8 OAP63032.1 - 1.8 8.9 14.5 0.39 11.1 4.2 2.3 2 0 0 2 2 2 0 YlqD protein DUF948 PF06103.11 OAP63032.1 - 2.2 8.6 4.0 27 5.1 0.1 2.6 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) CorA PF01544.18 OAP63032.1 - 3.9 6.7 6.0 1.2 8.3 0.3 2.1 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Golgin_A5 PF09787.9 OAP63032.1 - 5.1 6.5 18.4 0.94 8.9 1.4 2.1 2 0 0 2 2 2 0 Golgin subfamily A member 5 MscS_porin PF12795.7 OAP63032.1 - 5.2 6.5 27.4 0.26 10.8 6.5 2.8 2 1 0 2 2 2 0 Mechanosensitive ion channel porin domain EMP24_GP25L PF01105.24 OAP63032.1 - 6.4 6.7 7.5 7.6 6.4 0.1 2.5 2 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Hamartin PF04388.12 OAP63032.1 - 6.4 5.3 15.6 40 2.7 15.6 1.9 1 1 0 1 1 1 0 Hamartin protein Spc7 PF08317.11 OAP63032.1 - 9.3 5.0 17.8 3.9 6.3 8.7 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein FAM76 PF16046.5 OAP63032.1 - 9.6 5.5 7.5 9.6 5.5 6.3 1.6 1 1 0 1 1 1 0 FAM76 protein KilA-N PF04383.13 OAP63033.1 - 0.0006 19.6 0.5 0.0027 17.5 0.0 2.3 2 1 0 2 2 2 1 KilA-N domain PseudoU_synth_2 PF00849.22 OAP63034.1 - 8.4e-26 91.0 0.0 1.7e-25 90.0 0.0 1.5 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 OAP63034.1 - 3.2e-06 26.7 0.0 5.9e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 S4 domain Auto_anti-p27 PF06677.12 OAP63034.1 - 0.00017 21.7 0.2 0.00035 20.7 0.2 1.5 1 0 0 1 1 1 1 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Ribosomal_L32e PF01655.18 OAP63035.1 - 1.9e-47 160.2 0.8 1.9e-47 160.2 0.8 1.7 1 1 1 2 2 2 1 Ribosomal protein L32 GFO_IDH_MocA PF01408.22 OAP63036.1 - 2.8e-17 63.6 0.0 4.9e-17 62.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 OAP63036.1 - 0.0003 20.8 0.1 0.0013 18.8 0.0 1.9 1 1 1 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain Heme_oxygenase PF01126.20 OAP63037.1 - 3.9e-12 46.4 0.0 6.7e-12 45.6 0.0 1.3 1 1 0 1 1 1 1 Heme oxygenase FYVE_2 PF02318.16 OAP63038.1 - 0.074 13.3 12.7 1.3 9.2 3.6 2.4 2 0 0 2 2 2 0 FYVE-type zinc finger DUF3580 PF12117.8 OAP63038.1 - 0.31 11.3 4.5 4.3 7.6 5.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3580) zf-C2HE PF16278.5 OAP63038.1 - 2.1 8.9 0.0 2.1 8.9 0.0 3.2 4 0 0 4 4 4 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C3HC4_3 PF13920.6 OAP63038.1 - 2.4 8.1 20.7 2.4 8.1 4.3 2.7 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) HypA PF01155.19 OAP63038.1 - 4.2 7.4 15.1 1.8 8.6 1.0 2.5 2 1 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C3HC4 PF00097.25 OAP63038.1 - 4.2 7.3 22.8 3.3 7.7 5.9 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Zn_Tnp_IS91 PF14319.6 OAP63038.1 - 7.9 6.6 19.9 2.9 8.0 7.2 2.4 2 0 0 2 2 2 0 Transposase zinc-binding domain Adaptin_N PF01602.20 OAP63039.1 - 3.6e-104 349.2 0.1 4.5e-104 348.9 0.1 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 OAP63039.1 - 1.2e-15 58.0 0.7 7.8e-14 52.0 0.0 3.4 3 2 1 5 5 5 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 OAP63039.1 - 4.1e-09 36.7 1.1 0.00071 19.9 0.0 4.2 3 1 0 3 3 3 2 HEAT repeats HEAT PF02985.22 OAP63039.1 - 1.1e-06 28.4 2.0 0.19 12.1 0.0 5.7 6 0 0 6 6 6 2 HEAT repeat Cohesin_HEAT PF12765.7 OAP63039.1 - 0.0033 17.7 3.2 0.46 10.8 0.0 4.1 4 0 0 4 4 4 1 HEAT repeat associated with sister chromatid cohesion EH_Signature PF15611.6 OAP63039.1 - 0.022 14.2 0.1 0.04 13.3 0.1 1.4 1 0 0 1 1 1 0 EH_Signature domain Cnd3 PF12719.7 OAP63039.1 - 0.031 13.5 0.1 0.17 11.1 0.1 2.1 2 0 0 2 2 2 0 Nuclear condensing complex subunits, C-term domain HEAT_EZ PF13513.6 OAP63039.1 - 0.068 13.7 1.3 1.6e+02 3.0 0.0 4.6 5 0 0 5 5 4 0 HEAT-like repeat DNA_pol_phi PF04931.13 OAP63039.1 - 1.3 7.1 21.1 3.9 5.4 20.2 1.9 2 0 0 2 2 2 0 DNA polymerase phi Nop14 PF04147.12 OAP63039.1 - 1.5 7.0 16.7 2.8 6.1 16.7 1.4 1 0 0 1 1 1 0 Nop14-like family Paf1 PF03985.13 OAP63039.1 - 7.9 5.4 16.9 12 4.7 16.9 1.2 1 0 0 1 1 1 0 Paf1 Nuf2 PF03800.14 OAP63041.1 - 4e-40 137.1 0.3 1.3e-39 135.5 0.3 1.9 1 0 0 1 1 1 1 Nuf2 family DHR10 PF18595.1 OAP63041.1 - 4e-35 120.4 22.7 4e-35 120.4 22.7 4.9 4 1 0 4 4 4 1 Designed helical repeat protein 10 domain SlyX PF04102.12 OAP63041.1 - 0.023 15.3 1.2 0.023 15.3 1.2 6.0 2 2 3 5 5 5 0 SlyX HrpB7 PF09486.10 OAP63041.1 - 0.24 11.8 54.9 0.1 13.0 20.7 4.3 1 1 3 4 4 4 0 Bacterial type III secretion protein (HrpB7) GAS PF13851.6 OAP63041.1 - 6 6.2 60.1 8.8 5.6 29.0 3.3 1 1 3 4 4 4 0 Growth-arrest specific micro-tubule binding SepSecS PF05889.13 OAP63041.1 - 7 5.2 11.3 0.11 11.1 3.7 1.9 2 0 0 2 2 2 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS IF-2B PF01008.17 OAP63042.1 - 3.6e-32 111.7 0.0 6.4e-32 110.9 0.0 1.4 1 1 0 1 1 1 1 Initiation factor 2 subunit family GATA PF00320.27 OAP63043.1 - 2.6e-28 97.3 19.6 4.3e-14 51.8 4.2 2.5 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 OAP63043.1 - 1.8e-06 27.4 4.2 0.0026 17.3 0.1 2.5 2 0 0 2 2 2 2 TFIIB zinc-binding Zn-ribbon_8 PF09723.10 OAP63043.1 - 0.00012 22.2 3.0 0.13 12.4 0.3 2.8 2 0 0 2 2 2 2 Zinc ribbon domain ArfGap PF01412.18 OAP63043.1 - 0.0016 18.5 2.5 0.91 9.6 0.3 2.5 2 0 0 2 2 2 2 Putative GTPase activating protein for Arf Auto_anti-p27 PF06677.12 OAP63043.1 - 0.0016 18.6 6.1 0.11 12.6 0.7 2.4 2 0 0 2 2 2 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) OrfB_Zn_ribbon PF07282.11 OAP63043.1 - 0.003 17.5 6.2 0.27 11.2 0.5 2.6 2 0 0 2 2 2 2 Putative transposase DNA-binding domain eIF-5_eIF-2B PF01873.17 OAP63043.1 - 0.028 14.3 4.4 2.6 8.0 0.6 2.4 2 0 0 2 2 2 0 Domain found in IF2B/IF5 Nudix_N_2 PF14803.6 OAP63043.1 - 0.034 14.1 2.3 0.034 14.1 2.3 3.2 2 1 1 3 3 3 0 Nudix N-terminal DZR PF12773.7 OAP63043.1 - 0.14 12.2 10.7 1.5 8.9 0.9 3.0 1 1 2 3 3 3 0 Double zinc ribbon COPI_assoc PF08507.10 OAP63044.1 - 1.5e-30 105.9 4.7 1.6e-30 105.8 4.7 1.0 1 0 0 1 1 1 1 COPI associated protein Cg6151-P PF10233.9 OAP63044.1 - 0.11 12.8 8.1 0.17 12.2 8.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein CG6151-P OTU PF02338.19 OAP63045.1 - 3.1e-12 47.1 0.0 4.8e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease DUF5601 PF18151.1 OAP63045.1 - 0.049 13.9 0.1 0.1 12.9 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5601) DAO PF01266.24 OAP63046.1 - 1.1e-30 107.4 1.3 1.3e-30 107.2 1.3 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 OAP63046.1 - 0.00012 21.4 1.9 0.00012 21.4 0.1 2.0 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 OAP63046.1 - 0.00013 22.1 0.1 0.00042 20.5 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAP63046.1 - 0.00024 20.4 3.5 0.0011 18.3 0.0 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAP63046.1 - 0.00049 19.3 0.6 0.0008 18.6 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.19 OAP63046.1 - 0.13 11.4 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Thioredoxin PF00085.20 OAP63048.1 - 1.4e-28 98.9 0.3 1.8e-28 98.5 0.3 1.2 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 OAP63048.1 - 4.7e-07 29.4 0.1 5.1e-07 29.3 0.1 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 OAP63048.1 - 1.2e-06 28.9 0.1 2.3e-06 28.0 0.1 1.5 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 OAP63048.1 - 4.9e-06 26.8 0.1 7.9e-05 22.9 0.1 2.3 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.6 OAP63048.1 - 0.001 18.9 0.1 0.0013 18.5 0.1 1.4 1 1 0 1 1 1 1 Thioredoxin Redoxin PF08534.10 OAP63048.1 - 0.003 17.3 0.8 0.067 12.9 0.7 2.0 1 1 0 1 1 1 1 Redoxin Thioredoxin_7 PF13899.6 OAP63048.1 - 0.003 17.7 0.1 0.0051 17.0 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin-like TraF PF13728.6 OAP63048.1 - 0.0033 17.3 0.6 0.0075 16.1 0.6 1.5 1 1 0 1 1 1 1 F plasmid transfer operon protein DIM1 PF02966.16 OAP63048.1 - 0.015 15.0 0.0 0.018 14.8 0.0 1.2 1 0 0 1 1 1 0 Mitosis protein DIM1 Glutaredoxin PF00462.24 OAP63048.1 - 0.54 10.5 2.9 1.9 8.8 2.9 2.0 1 1 0 1 1 1 0 Glutaredoxin WD40 PF00400.32 OAP63049.1 - 1.6e-28 98.3 4.3 3.5e-05 24.5 0.1 7.5 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAP63049.1 - 8.1e-08 32.5 0.0 0.29 11.5 0.0 4.6 4 1 2 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 OAP63049.1 - 0.00058 18.7 0.0 0.7 8.6 0.0 2.7 2 0 0 2 2 2 2 Nup133 N terminal like eIF2A PF08662.11 OAP63049.1 - 0.0045 16.9 0.0 0.03 14.2 0.0 2.2 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Lactonase PF10282.9 OAP63049.1 - 0.028 13.7 0.0 5.6 6.1 0.0 3.1 4 0 0 4 4 4 0 Lactonase, 7-bladed beta-propeller Ge1_WD40 PF16529.5 OAP63049.1 - 0.18 10.7 0.0 13 4.6 0.0 2.9 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein TF_Zn_Ribbon PF08271.12 OAP63049.1 - 0.34 10.5 1.7 0.69 9.5 1.7 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding zinc_ribbon_4 PF13717.6 OAP63049.1 - 2.1 8.4 6.1 2.5 8.1 0.5 2.5 1 1 1 2 2 2 0 zinc-ribbon domain DCP2 PF05026.13 OAP63050.1 - 7.6e-31 106.3 1.2 1.2e-30 105.6 0.6 1.7 2 0 0 2 2 2 1 Dcp2, box A domain NUDIX PF00293.28 OAP63050.1 - 5.6e-18 65.2 0.1 1.2e-17 64.2 0.1 1.5 1 0 0 1 1 1 1 NUDIX domain DUF4112 PF13430.6 OAP63051.1 - 5.1e-31 107.1 0.1 6.9e-31 106.6 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) CTU2 PF10288.9 OAP63052.1 - 9.1e-11 42.0 2.3 2.1e-09 37.6 0.0 2.7 2 1 1 3 3 3 1 Cytoplasmic tRNA 2-thiolation protein 2 Pilus_CpaD PF09476.10 OAP63052.1 - 0.037 13.8 0.1 0.06 13.1 0.1 1.2 1 0 0 1 1 1 0 Pilus biogenesis CpaD protein (pilus_cpaD) Auto_anti-p27 PF06677.12 OAP63052.1 - 0.057 13.6 1.3 0.057 13.6 1.3 2.6 2 1 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DZR PF12773.7 OAP63052.1 - 0.8 9.8 7.5 0.76 9.9 1.0 2.4 2 0 0 2 2 2 0 Double zinc ribbon zf-FPG_IleRS PF06827.14 OAP63052.1 - 8.6 6.3 7.9 1.6 8.7 1.0 2.4 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS adh_short_C2 PF13561.6 OAP63054.1 - 5.8e-35 120.9 0.0 6.9e-34 117.4 0.0 2.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP63054.1 - 1.6e-34 119.1 0.0 5.3e-34 117.4 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAP63054.1 - 9.7e-10 38.6 0.1 1.7e-09 37.9 0.1 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OAP63054.1 - 6.2e-06 25.6 0.0 7.5e-05 22.0 0.0 2.0 1 1 1 2 2 2 1 Polysaccharide biosynthesis protein NmrA PF05368.13 OAP63054.1 - 0.0034 17.0 0.2 0.58 9.7 0.2 2.1 2 0 0 2 2 2 2 NmrA-like family Epimerase PF01370.21 OAP63054.1 - 0.0058 16.1 0.0 0.0086 15.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OAP63054.1 - 0.074 12.0 0.1 0.12 11.3 0.1 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family GCSF PF16647.5 OAP63054.1 - 0.075 12.9 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Granulocyte colony-stimulating factor Shikimate_DH PF01488.20 OAP63054.1 - 0.094 12.8 0.1 0.16 12.0 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase HMG_CoA_synt_C PF08540.10 OAP63055.1 - 6.5e-105 350.7 0.5 1.4e-103 346.4 0.5 2.1 1 1 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 OAP63055.1 - 1.1e-95 318.5 0.2 1.5e-95 318.0 0.2 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal NTF2 PF02136.20 OAP63056.1 - 8.8e-34 116.6 0.4 1.4e-33 116.0 0.4 1.3 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4440 PF14534.6 OAP63056.1 - 0.024 15.0 0.0 0.051 14.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) Cg6151-P PF10233.9 OAP63057.1 - 2.9e-42 143.5 13.5 3.4e-42 143.3 13.5 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P COPI_assoc PF08507.10 OAP63057.1 - 0.63 10.1 14.3 0.95 9.5 13.8 1.6 1 1 0 1 1 1 0 COPI associated protein DHHC PF01529.20 OAP63057.1 - 1 9.5 6.6 1.4 9.0 6.6 1.3 1 0 0 1 1 1 0 DHHC palmitoyltransferase DUF2207 PF09972.9 OAP63057.1 - 7.7 5.1 11.6 12 4.5 11.6 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF3433 PF11915.8 OAP63058.1 - 1.2e-30 105.8 17.7 1.9e-18 66.7 1.5 3.7 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) TPR_10 PF13374.6 OAP63059.1 - 1.4e-85 279.1 13.5 4.9e-12 45.3 0.1 8.5 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_12 PF13424.6 OAP63059.1 - 7.5e-74 244.0 27.6 2.8e-16 59.6 0.3 8.3 2 1 7 9 9 9 8 Tetratricopeptide repeat TPR_7 PF13176.6 OAP63059.1 - 3.2e-24 83.1 8.9 0.0041 17.1 0.0 8.7 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_1 PF00515.28 OAP63059.1 - 9.1e-14 50.6 18.8 0.0021 17.8 1.3 8.9 10 0 0 10 10 9 5 Tetratricopeptide repeat NB-ARC PF00931.22 OAP63059.1 - 1.5e-12 47.3 0.5 1.4e-11 44.1 0.0 2.7 3 0 0 3 3 3 1 NB-ARC domain TPR_2 PF07719.17 OAP63059.1 - 5.5e-12 44.8 19.4 0.21 11.8 1.4 8.7 8 0 0 8 8 8 3 Tetratricopeptide repeat HET PF06985.11 OAP63059.1 - 1.1e-11 45.3 9.6 2.2e-09 37.8 1.1 3.1 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) TPR_4 PF07721.14 OAP63059.1 - 1.5e-10 40.7 4.1 2.2 9.2 0.0 7.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_MalT PF17874.1 OAP63059.1 - 1.5e-09 37.7 13.8 1.3e-05 24.8 2.0 2.9 1 1 2 3 3 3 3 MalT-like TPR region TPR_19 PF14559.6 OAP63059.1 - 1.9e-09 37.9 4.6 0.096 13.2 0.0 7.9 6 2 4 10 10 8 1 Tetratricopeptide repeat TPR_8 PF13181.6 OAP63059.1 - 8.1e-08 31.9 10.7 0.0018 18.4 0.3 7.6 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_16 PF13432.6 OAP63059.1 - 6.4e-07 29.9 2.1 58 4.4 0.0 8.0 9 0 0 9 9 8 0 Tetratricopeptide repeat NACHT PF05729.12 OAP63059.1 - 7.6e-06 25.9 0.0 2e-05 24.5 0.0 1.8 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 OAP63059.1 - 1.4e-05 25.6 1.8 8.1e-05 23.1 1.8 2.4 1 1 0 1 1 1 1 AAA ATPase domain TPR_17 PF13431.6 OAP63059.1 - 7.4e-05 22.9 4.9 17 6.0 0.0 6.8 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_14 PF13428.6 OAP63059.1 - 0.00033 21.2 14.8 3.9 8.5 0.0 8.6 9 0 0 9 9 8 1 Tetratricopeptide repeat AAA_22 PF13401.6 OAP63059.1 - 0.0008 19.7 0.0 0.0062 16.8 0.0 2.2 1 1 1 2 2 2 1 AAA domain CutA1 PF03091.15 OAP63059.1 - 0.00093 19.0 11.7 6 6.8 0.1 6.5 5 1 1 7 7 7 1 CutA1 divalent ion tolerance protein ATPase_2 PF01637.18 OAP63059.1 - 0.067 13.1 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea RPN6_N PF18055.1 OAP63059.1 - 0.37 11.2 1.6 30 5.0 0.0 3.9 5 0 0 5 5 4 0 26S proteasome regulatory subunit RPN6 N-terminal domain cwf21 PF08312.12 OAP63059.1 - 0.85 9.8 4.1 16 5.8 0.1 3.7 2 1 2 4 4 4 0 cwf21 domain DIOX_N PF14226.6 OAP63060.1 - 3e-27 95.7 0.1 4.6e-27 95.1 0.1 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OAP63060.1 - 1.8e-21 76.5 0.0 3e-21 75.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Amidohydro_2 PF04909.14 OAP63061.1 - 9e-28 97.9 0.0 2e-27 96.8 0.0 1.5 1 1 0 1 1 1 1 Amidohydrolase TatD_DNase PF01026.21 OAP63061.1 - 0.19 11.1 0.0 8.5 5.7 0.0 2.2 2 0 0 2 2 2 0 TatD related DNase Mei4 PF13971.6 OAP63062.1 - 0.005 16.4 0.0 0.011 15.3 0.0 1.6 1 0 0 1 1 1 1 Meiosis-specific protein Mei4 NUDE_C PF04880.13 OAP63062.1 - 0.0087 16.6 1.3 0.018 15.6 1.3 1.4 1 0 0 1 1 1 1 NUDE protein, C-terminal conserved region TetR_C_27 PF17935.1 OAP63062.1 - 0.11 12.5 0.0 0.26 11.4 0.0 1.6 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain DnaJ PF00226.31 OAP63063.1 - 2.4e-19 69.2 0.6 5.3e-19 68.1 0.2 1.9 2 0 0 2 2 2 1 DnaJ domain DUF4778 PF16008.5 OAP63063.1 - 0.036 14.1 5.1 0.048 13.7 5.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) Med9 PF07544.13 OAP63063.1 - 0.038 14.1 1.6 0.077 13.1 1.6 1.6 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 DUF2161 PF09929.9 OAP63063.1 - 0.26 11.4 4.1 0.62 10.2 4.1 1.7 1 0 0 1 1 1 0 Putative PD-(D/E)XK phosphodiesterase (DUF2161) Presenilin PF01080.17 OAP63063.1 - 0.41 9.3 2.2 0.49 9.1 2.2 1.1 1 0 0 1 1 1 0 Presenilin GCV_T PF01571.21 OAP63064.1 - 8.2e-07 28.7 0.0 1.3e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain PNISR PF15996.5 OAP63064.1 - 0.71 10.1 5.3 1.1 9.5 5.3 1.2 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR ABM PF03992.16 OAP63065.1 - 0.0018 18.3 0.3 0.0027 17.8 0.3 1.3 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase ABC2_membrane PF01061.24 OAP63066.1 - 1.1e-82 276.6 57.9 4.8e-43 147.0 18.0 3.4 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 OAP63066.1 - 2.2e-35 122.2 0.0 2.7e-16 60.3 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 OAP63066.1 - 2.4e-31 107.5 11.9 1.6e-29 101.6 0.0 3.4 4 0 0 4 4 2 2 CDR ABC transporter ABC_trans_N PF14510.6 OAP63066.1 - 1.7e-13 50.9 0.0 5.6e-13 49.3 0.0 1.9 1 0 0 1 1 1 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 OAP63066.1 - 3e-07 29.9 45.3 1.9e-05 23.9 18.5 2.5 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_16 PF13191.6 OAP63066.1 - 5.8e-06 26.8 0.3 0.01 16.3 0.1 2.6 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 OAP63066.1 - 1.9e-05 24.7 0.0 0.0021 18.0 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_18 PF13238.6 OAP63066.1 - 2.2e-05 25.0 0.0 0.0037 17.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 OAP63066.1 - 2.8e-05 23.8 0.2 0.0071 15.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 OAP63066.1 - 5.6e-05 23.3 0.1 0.058 13.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.6 OAP63066.1 - 0.00012 22.0 0.0 1.2 8.9 0.0 3.5 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 OAP63066.1 - 0.00013 21.6 1.5 0.054 13.2 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 OAP63066.1 - 0.0012 19.1 0.4 1.3 9.3 0.2 2.9 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.6 OAP63066.1 - 0.011 16.1 0.2 0.48 10.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 OAP63066.1 - 0.017 14.7 1.4 0.2 11.3 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 OAP63066.1 - 0.027 14.4 1.3 4.8 7.1 0.3 2.7 2 0 0 2 2 2 0 NACHT domain SMC_N PF02463.19 OAP63066.1 - 0.029 13.8 0.0 0.86 9.0 0.0 2.7 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 OAP63066.1 - 0.03 14.4 0.1 12 6.0 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase dNK PF01712.19 OAP63066.1 - 0.11 12.3 0.0 15 5.4 0.0 2.3 2 0 0 2 2 2 0 Deoxynucleoside kinase AAA PF00004.29 OAP63066.1 - 0.12 12.8 0.2 13 6.2 0.0 2.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Ploopntkinase3 PF18751.1 OAP63066.1 - 0.13 12.2 0.1 0.88 9.4 0.0 2.2 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_30 PF13604.6 OAP63066.1 - 0.18 11.5 1.6 2.6 7.7 0.4 2.4 2 0 0 2 2 2 0 AAA domain SRP9-21 PF05486.12 OAP63067.1 - 4.8e-29 100.6 0.6 7.2e-29 100.0 0.6 1.2 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) Ribonuc_red_sm PF00268.21 OAP63068.1 - 6.9e-120 399.7 1.6 9.7e-120 399.2 1.6 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain RE_XcyI PF09571.10 OAP63068.1 - 0.066 12.5 0.1 1 8.5 0.0 2.1 2 0 0 2 2 2 0 XcyI restriction endonuclease Mito_carr PF00153.27 OAP63069.1 - 1.8e-54 181.6 3.0 1.3e-18 66.7 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein WD40 PF00400.32 OAP63070.1 - 1.5e-13 51.0 3.4 3.2e-05 24.6 0.1 4.6 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAP63070.1 - 1.8e-07 31.4 0.0 0.0033 17.7 0.0 3.6 2 2 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 OAP63070.1 - 0.04 12.2 0.0 0.093 11.0 0.0 1.5 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz MRG PF05712.13 OAP63070.1 - 0.059 12.7 0.0 0.083 12.2 0.0 1.2 1 0 0 1 1 1 0 MRG WDCP PF15390.6 OAP63070.1 - 0.17 10.2 0.0 0.3 9.4 0.0 1.3 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family DUF1308 PF07000.11 OAP63071.1 - 8e-07 29.1 2.2 5.2e-05 23.3 0.0 3.7 4 1 0 4 4 4 1 Protein of unknown function (DUF1308) DUF5614 PF18474.1 OAP63071.1 - 0.00048 19.5 0.1 0.86 8.9 0.1 3.5 2 1 1 3 3 3 2 Family of unknown function (DUF5614) IL6 PF00489.17 OAP63071.1 - 0.045 13.3 0.4 0.11 12.0 0.0 1.8 2 0 0 2 2 2 0 Interleukin-6/G-CSF/MGF family Lung_7-TM_R PF06814.13 OAP63072.1 - 2.7e-70 236.9 17.7 3.2e-70 236.7 17.7 1.0 1 0 0 1 1 1 1 Lung seven transmembrane receptor OHCU_decarbox PF09349.10 OAP63073.1 - 2e-31 109.6 0.2 2.5e-31 109.3 0.2 1.0 1 0 0 1 1 1 1 OHCU decarboxylase Cofilin_ADF PF00241.20 OAP63074.1 - 0.17 11.7 0.0 0.34 10.7 0.0 1.5 1 0 0 1 1 1 0 Cofilin/tropomyosin-type actin-binding protein Thioredoxin PF00085.20 OAP63075.1 - 4.2e-61 203.4 0.0 1.7e-29 101.9 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.12 OAP63075.1 - 2.4e-22 79.7 0.5 1.2e-21 77.3 0.3 2.1 2 0 0 2 2 2 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.6 OAP63075.1 - 6.5e-17 62.0 0.1 3.3e-07 30.7 0.0 3.1 3 1 0 3 3 3 2 Thioredoxin-like domain OST3_OST6 PF04756.13 OAP63075.1 - 2.4e-13 50.1 0.0 3.1e-06 26.7 0.0 2.1 1 1 1 2 2 2 2 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 OAP63075.1 - 5.3e-09 36.1 0.0 0.0013 18.6 0.0 2.4 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_8 PF13905.6 OAP63075.1 - 1.6e-08 34.7 0.0 0.0096 16.2 0.0 3.3 2 1 1 3 3 3 2 Thioredoxin-like Thioredoxin_7 PF13899.6 OAP63075.1 - 5.6e-08 32.9 0.0 0.0018 18.4 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin-like Redoxin PF08534.10 OAP63075.1 - 2.5e-07 30.5 0.3 0.0051 16.5 0.0 2.3 2 0 0 2 2 2 2 Redoxin Thioredoxin_6 PF13848.6 OAP63075.1 - 0.00043 20.2 0.0 0.31 10.9 0.0 2.8 2 2 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_4 PF13462.6 OAP63075.1 - 0.00046 20.4 0.2 2.8 8.1 0.1 3.5 3 1 1 4 4 4 2 Thioredoxin Thioredoxin_9 PF14595.6 OAP63075.1 - 0.00077 19.2 0.0 0.53 10.1 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin TraF PF13728.6 OAP63075.1 - 0.0017 18.2 0.0 0.059 13.2 0.0 2.3 2 0 0 2 2 2 1 F plasmid transfer operon protein HyaE PF07449.11 OAP63075.1 - 0.0023 17.9 0.0 0.096 12.7 0.0 2.5 2 0 0 2 2 2 1 Hydrogenase-1 expression protein HyaE Thioredoxin_3 PF13192.6 OAP63075.1 - 0.0029 17.6 0.0 0.5 10.5 0.0 2.8 2 0 0 2 2 2 1 Thioredoxin domain Glutaredoxin PF00462.24 OAP63075.1 - 0.011 16.0 0.6 6.9 7.0 0.1 3.1 2 2 0 2 2 2 0 Glutaredoxin DDE_Tnp_1_2 PF13586.6 OAP63075.1 - 0.1 12.9 0.0 4.8 7.6 0.0 2.5 2 0 0 2 2 2 0 Transposase DDE domain HSBP1 PF06825.12 OAP63076.1 - 6.8e-12 45.0 1.3 1.8e-11 43.7 0.6 1.8 1 1 1 2 2 2 1 Heat shock factor binding protein 1 PhoU_div PF01865.16 OAP63076.1 - 0.01 15.2 0.0 0.012 15.0 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function DUF47 Lipoprotein_7 PF01540.16 OAP63076.1 - 0.11 11.8 0.0 0.13 11.6 0.0 1.0 1 0 0 1 1 1 0 Adhesin lipoprotein FAD_binding_3 PF01494.19 OAP63079.1 - 4.8e-94 315.5 0.0 6.1e-94 315.1 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAP63079.1 - 1.6e-10 41.1 2.0 0.00022 20.9 0.0 2.7 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 OAP63079.1 - 5.9e-07 30.0 0.9 0.0036 17.8 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAP63079.1 - 5.9e-07 29.0 3.0 0.017 14.4 0.1 2.5 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAP63079.1 - 6.2e-06 25.5 0.7 0.0098 15.0 0.3 2.2 1 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 OAP63079.1 - 0.00026 21.1 0.1 0.00063 19.9 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 OAP63079.1 - 0.003 17.0 0.2 0.036 13.4 0.2 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 OAP63079.1 - 0.0062 15.8 0.9 0.24 10.6 0.2 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 OAP63079.1 - 0.022 14.0 0.2 0.15 11.3 0.1 2.0 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Trp_halogenase PF04820.14 OAP63079.1 - 0.031 13.1 0.8 2.2 7.0 0.1 2.6 3 0 0 3 3 3 0 Tryptophan halogenase HI0933_like PF03486.14 OAP63079.1 - 0.04 12.6 0.5 4.8 5.8 0.2 2.2 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.17 OAP63079.1 - 0.059 12.6 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Ebp2 PF05890.12 OAP63080.1 - 3.9e-86 288.9 12.1 3.9e-86 288.9 12.1 2.0 2 0 0 2 2 2 1 Eukaryotic rRNA processing protein EBP2 CPSF100_C PF13299.6 OAP63080.1 - 4.5 7.4 17.9 7.8 6.7 6.9 2.7 2 1 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal DNMT1-RFD PF12047.8 OAP63081.1 - 0.00029 20.9 0.0 0.00077 19.5 0.0 1.7 1 0 0 1 1 1 1 Cytosine specific DNA methyltransferase replication foci domain SDA1 PF05285.12 OAP63081.1 - 0.014 14.9 9.7 0.018 14.5 9.7 1.2 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 OAP63081.1 - 0.03 12.6 7.3 0.04 12.2 7.3 1.1 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 OAP63081.1 - 0.043 11.9 17.0 0.07 11.2 17.0 1.3 1 0 0 1 1 1 0 DNA polymerase phi CPSF100_C PF13299.6 OAP63081.1 - 0.059 13.6 5.2 0.13 12.4 5.2 1.5 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Nop14 PF04147.12 OAP63081.1 - 0.12 10.5 14.5 0.19 9.9 14.5 1.3 1 0 0 1 1 1 0 Nop14-like family PPP4R2 PF09184.11 OAP63081.1 - 0.39 10.3 11.8 0.71 9.4 11.8 1.4 1 0 0 1 1 1 0 PPP4R2 Imm5 PF14423.6 OAP63081.1 - 0.7 10.1 4.5 2.4 8.4 3.6 2.0 2 0 0 2 2 2 0 Immunity protein Imm5 DUF913 PF06025.12 OAP63081.1 - 0.93 8.4 6.2 0.18 10.7 2.7 1.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) CobT PF06213.12 OAP63081.1 - 1.1 8.6 19.7 0.57 9.5 17.3 1.6 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT RR_TM4-6 PF06459.12 OAP63081.1 - 1.3 8.8 7.7 0.58 9.9 5.2 1.7 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 SAPS PF04499.15 OAP63081.1 - 1.8 7.2 7.8 2.6 6.7 7.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Presenilin PF01080.17 OAP63081.1 - 3 6.5 3.4 4.6 5.9 3.4 1.2 1 0 0 1 1 1 0 Presenilin PI3K_1B_p101 PF10486.9 OAP63081.1 - 3.1 5.5 6.3 4.3 5.0 6.3 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit RRN3 PF05327.11 OAP63081.1 - 4.7 5.6 11.8 0.95 7.9 8.1 1.6 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 TLP-20 PF06088.11 OAP63081.1 - 9 6.1 7.6 3.4 7.5 4.7 1.8 3 0 0 3 3 3 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) TruB_N PF01509.18 OAP63082.1 - 9.2e-43 146.2 0.0 7.8e-42 143.2 0.0 2.1 1 1 1 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) DUF1857 PF08982.11 OAP63082.1 - 0.021 14.6 0.4 0.055 13.3 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1857) TruB_C_2 PF16198.5 OAP63082.1 - 0.043 14.0 0.0 0.088 13.0 0.0 1.5 1 0 0 1 1 1 0 tRNA pseudouridylate synthase B C-terminal domain DOT1 PF08123.13 OAP63083.1 - 6.8e-73 244.6 0.0 1.2e-72 243.8 0.0 1.4 1 0 0 1 1 1 1 Histone methylation protein DOT1 ORC6 PF05460.13 OAP63083.1 - 1.4 8.1 12.7 2.2 7.5 12.7 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) ATG16 PF08614.11 OAP63084.1 - 3.5e-50 171.0 13.2 4e-50 170.8 13.2 1.0 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) UPF0242 PF06785.11 OAP63084.1 - 0.00027 21.1 13.6 0.0044 17.1 6.1 2.8 1 1 1 3 3 3 2 Uncharacterised protein family (UPF0242) N-terminus GvpG PF05120.12 OAP63084.1 - 0.0013 18.7 6.8 0.22 11.6 3.3 2.6 1 1 0 2 2 2 2 Gas vesicle protein G Lebercilin PF15619.6 OAP63084.1 - 0.0086 15.7 16.2 0.0086 15.7 16.2 1.7 2 0 0 2 2 2 1 Ciliary protein causing Leber congenital amaurosis disease CCDC144C PF14915.6 OAP63084.1 - 0.013 14.6 11.2 0.022 13.9 11.2 1.3 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region Golgin_A5 PF09787.9 OAP63084.1 - 0.023 14.2 8.5 0.035 13.6 8.5 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF3584 PF12128.8 OAP63084.1 - 0.042 11.4 11.2 0.052 11.1 11.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) KIAA1430 PF13879.6 OAP63084.1 - 0.046 14.5 1.3 0.046 14.5 1.3 2.3 1 1 1 2 2 2 0 KIAA1430 homologue TMF_DNA_bd PF12329.8 OAP63084.1 - 0.099 12.6 14.7 0.16 12.0 0.9 3.1 3 1 1 4 4 4 0 TATA element modulatory factor 1 DNA binding TPR_MLP1_2 PF07926.12 OAP63084.1 - 0.16 12.0 19.4 0.1 12.7 6.4 3.2 2 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein Atg14 PF10186.9 OAP63084.1 - 0.18 10.9 8.8 0.28 10.2 8.8 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4201 PF13870.6 OAP63084.1 - 0.19 11.4 16.6 0.032 13.9 12.9 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) Spc7 PF08317.11 OAP63084.1 - 0.27 10.1 15.4 0.07 12.0 11.5 1.8 2 0 0 2 2 2 0 Spc7 kinetochore protein HAUS-augmin3 PF14932.6 OAP63084.1 - 0.62 9.6 10.3 1.7 8.2 10.3 1.7 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 LMBR1 PF04791.16 OAP63084.1 - 0.67 8.8 1.0 0.7 8.7 1.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein ZapB PF06005.12 OAP63084.1 - 0.68 10.4 17.1 0.39 11.2 0.9 3.7 2 1 2 4 4 4 0 Cell division protein ZapB SOAR PF16533.5 OAP63084.1 - 1.1 9.3 7.8 0.44 10.5 0.7 2.6 1 1 1 2 2 2 0 STIM1 Orai1-activating region JAKMIP_CC3 PF16034.5 OAP63084.1 - 1.1 9.1 15.4 6.8 6.6 15.4 2.0 1 1 0 1 1 1 0 JAKMIP CC3 domain Cnn_1N PF07989.11 OAP63084.1 - 1.5 9.0 15.6 1.6 8.9 3.6 3.7 2 1 1 3 3 3 0 Centrosomin N-terminal motif 1 DUF4407 PF14362.6 OAP63084.1 - 1.7 7.9 15.1 3.2 7.0 15.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) FUSC PF04632.12 OAP63084.1 - 2.2 6.7 5.3 3.9 5.9 5.3 1.5 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF2570 PF10828.8 OAP63084.1 - 3.2 7.6 8.7 1.6 8.6 2.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2570) Fez1 PF06818.15 OAP63084.1 - 4.3 7.7 13.2 5.9 7.3 12.2 1.7 1 1 0 1 1 1 0 Fez1 FAM76 PF16046.5 OAP63084.1 - 5.7 6.2 9.1 7.9 5.7 9.1 1.3 1 1 0 1 1 1 0 FAM76 protein CENP-H PF05837.12 OAP63084.1 - 6.7 7.2 19.3 8.1 6.9 5.7 3.0 2 1 1 3 3 3 0 Centromere protein H (CENP-H) YabA PF06156.13 OAP63084.1 - 8.9 7.0 12.0 19 5.9 5.5 2.8 2 1 1 3 3 3 0 Initiation control protein YabA DUF4164 PF13747.6 OAP63084.1 - 9.3 6.6 22.0 1 9.7 6.7 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4164) Ras PF00071.22 OAP63085.1 - 2.6e-57 193.0 0.1 3e-57 192.8 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAP63085.1 - 5e-33 113.9 0.0 7.4e-33 113.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAP63085.1 - 2e-13 50.2 0.0 2.3e-13 50.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OAP63085.1 - 2.1e-08 34.3 0.0 2.9e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OAP63085.1 - 5.8e-07 29.1 0.0 7.2e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 OAP63085.1 - 5.7e-06 26.0 0.0 0.00015 21.3 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OAP63085.1 - 1.5e-05 25.0 0.0 0.0021 18.0 0.1 2.3 1 1 0 2 2 2 1 RsgA GTPase cobW PF02492.19 OAP63085.1 - 0.00086 18.9 0.0 0.0071 16.0 0.0 2.0 1 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 OAP63085.1 - 0.0013 18.5 0.0 0.1 12.4 0.1 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 OAP63085.1 - 0.0026 17.6 0.1 0.09 12.5 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein SRPRB PF09439.10 OAP63085.1 - 0.0034 16.8 0.0 0.0043 16.5 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 OAP63085.1 - 0.0083 16.5 0.0 0.012 16.0 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain Septin PF00735.18 OAP63085.1 - 0.012 14.9 0.1 0.025 13.8 0.1 1.5 1 0 0 1 1 1 0 Septin AAA_22 PF13401.6 OAP63085.1 - 0.018 15.3 0.0 0.03 14.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 OAP63085.1 - 0.02 14.4 0.1 0.034 13.7 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 OAP63085.1 - 0.02 14.6 0.0 0.034 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 OAP63085.1 - 0.066 13.1 0.1 0.11 12.4 0.1 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea NTPase_1 PF03266.15 OAP63085.1 - 0.068 13.1 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 NTPase TniB PF05621.11 OAP63085.1 - 0.11 11.9 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein AAA_5 PF07728.14 OAP63085.1 - 0.11 12.5 0.0 0.24 11.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 OAP63085.1 - 0.12 12.3 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 NACHT domain NB-ARC PF00931.22 OAP63085.1 - 0.14 11.3 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain MCM PF00493.23 OAP63085.1 - 0.17 10.9 0.1 0.26 10.4 0.1 1.2 1 0 0 1 1 1 0 MCM P-loop domain WD40 PF00400.32 OAP63086.1 - 9.8e-39 130.7 16.6 2.4e-05 25.0 1.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAP63086.1 - 6.8e-15 55.1 0.0 0.00034 20.9 0.1 5.1 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OAP63086.1 - 1.5e-05 24.9 0.0 0.098 12.5 0.0 3.0 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 OAP63086.1 - 0.0021 17.4 0.0 0.077 12.3 0.0 2.8 2 1 1 3 3 3 1 WD40-like domain Ge1_WD40 PF16529.5 OAP63086.1 - 0.014 14.3 0.1 17 4.2 0.0 3.7 3 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF423 PF04241.15 OAP63087.1 - 2e-25 88.8 1.6 2.8e-25 88.3 1.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF423) Epimerase PF01370.21 OAP63088.1 - 0.00071 19.1 0.0 0.0027 17.2 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family zf-MYND PF01753.18 OAP63089.1 - 6e-08 32.6 20.3 1.3e-07 31.6 20.3 1.6 1 0 0 1 1 1 1 MYND finger DIOX_N PF14226.6 OAP63090.1 - 2.3e-19 70.3 0.0 3.7e-19 69.6 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OAP63090.1 - 1.4e-13 51.2 0.0 2.4e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MKT1_C PF12246.8 OAP63091.1 - 1.1e-56 191.8 0.0 1.5e-56 191.4 0.0 1.2 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.8 OAP63091.1 - 1.5e-26 92.6 0.0 3.7e-26 91.3 0.0 1.7 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_I PF00867.18 OAP63091.1 - 0.00018 21.8 0.1 0.00051 20.3 0.1 1.8 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 OAP63091.1 - 0.0013 19.1 0.0 0.0032 17.9 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain EamA PF00892.20 OAP63092.1 - 5.4e-10 39.6 35.1 4e-06 27.0 8.1 3.1 3 0 0 3 3 3 3 EamA-like transporter family DUF3955 PF13127.6 OAP63092.1 - 2.5e-09 36.8 2.2 2.5e-09 36.8 2.2 2.9 4 0 0 4 4 4 1 Protein of unknown function (DUF3955) UAA PF08449.11 OAP63092.1 - 0.0024 17.1 5.1 0.0044 16.3 5.1 1.4 1 0 0 1 1 1 1 UAA transporter family SLC35F PF06027.12 OAP63092.1 - 0.0029 17.2 7.5 0.052 13.1 3.9 3.0 2 1 0 2 2 2 1 Solute carrier family 35 PUNUT PF16913.5 OAP63092.1 - 4.3 6.5 10.0 0.036 13.3 1.3 1.9 3 0 0 3 3 3 0 Purine nucleobase transmembrane transport RCC1_2 PF13540.6 OAP63093.1 - 7.2e-14 51.2 10.5 0.00021 21.0 0.0 5.1 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat F-box PF00646.33 OAP63093.1 - 1.3e-05 24.9 0.0 3.3e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 F-box domain RCC1 PF00415.18 OAP63093.1 - 0.0016 19.0 0.8 0.66 10.6 0.1 4.1 5 0 0 5 5 5 1 Regulator of chromosome condensation (RCC1) repeat F-box-like PF12937.7 OAP63093.1 - 0.012 15.5 1.6 0.02 14.8 0.3 2.0 2 0 0 2 2 2 0 F-box-like Ran_BP1 PF00638.18 OAP63094.1 - 8.1e-51 171.4 1.3 1.4e-50 170.6 1.3 1.4 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.23 OAP63094.1 - 8.3e-05 22.5 0.1 0.0006 19.7 0.1 2.1 1 1 0 1 1 1 1 WH1 domain VID27_PH PF17747.1 OAP63094.1 - 0.0011 19.2 0.0 0.0017 18.6 0.0 1.3 1 0 0 1 1 1 1 VID27 PH-like domain CDC27 PF09507.10 OAP63094.1 - 0.0081 15.6 21.9 0.011 15.2 21.9 1.1 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 PPP4R2 PF09184.11 OAP63094.1 - 8.7 5.8 18.5 0.89 9.1 14.0 1.5 2 0 0 2 2 2 0 PPP4R2 YEATS PF03366.16 OAP63095.1 - 6.9e-16 58.0 0.0 1.2e-15 57.2 0.0 1.4 1 0 0 1 1 1 1 YEATS family BET PF17035.5 OAP63095.1 - 6.1e-05 23.1 0.8 0.00022 21.3 0.2 2.2 2 0 0 2 2 2 1 Bromodomain extra-terminal - transcription regulation Phosducin PF02114.16 OAP63096.1 - 4.8e-11 42.1 0.3 1.2e-10 40.9 0.0 1.7 2 0 0 2 2 2 1 Phosducin LigB PF02900.18 OAP63096.1 - 0.03 13.4 0.0 0.054 12.6 0.0 1.3 1 0 0 1 1 1 0 Catalytic LigB subunit of aromatic ring-opening dioxygenase PTCB-BRCT PF12738.7 OAP63097.1 - 4.2e-45 151.5 0.3 1.8e-20 72.6 0.1 4.3 4 0 0 4 4 4 4 twin BRCT domain BRCT PF00533.26 OAP63097.1 - 4.9e-30 103.7 0.0 1.7e-10 41.1 0.0 4.3 4 0 0 4 4 4 4 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 OAP63097.1 - 3.1e-16 59.6 0.1 0.00016 22.0 0.0 4.3 4 0 0 4 4 4 4 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 OAP63097.1 - 1.6e-06 28.3 0.2 1.7 9.0 0.0 4.3 4 0 0 4 4 4 2 DNA ligase 3 BRCT domain RTT107_BRCT_5 PF16770.5 OAP63097.1 - 0.018 14.9 0.1 1 9.3 0.0 3.4 4 0 0 4 4 4 0 Regulator of Ty1 transposition protein 107 BRCT domain DUF5642 PF18702.1 OAP63097.1 - 0.11 12.3 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5642) Arrestin_C PF02752.22 OAP63098.1 - 2.5e-18 66.8 0.0 8.5e-18 65.1 0.0 2.0 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 OAP63098.1 - 2.4e-08 34.2 0.0 6.4e-05 23.0 0.0 2.5 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Mhr1 PF12829.7 OAP63099.1 - 2e-26 91.9 0.0 4.4e-26 90.8 0.0 1.6 1 0 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination Nbl1_Borealin_N PF10444.9 OAP63099.1 - 0.36 10.5 3.2 1 9.0 3.2 1.8 1 0 0 1 1 1 0 Nbl1 / Borealin N terminal DUF883 PF05957.13 OAP63099.1 - 3.7 8.2 7.6 6.5 7.4 0.6 3.0 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) PH PF00169.29 OAP63100.1 - 1.2e-30 106.1 1.0 4e-15 56.2 0.2 2.3 2 0 0 2 2 2 2 PH domain PH_11 PF15413.6 OAP63100.1 - 2.1e-09 37.8 4.7 0.00096 19.5 1.6 3.6 2 2 0 2 2 2 2 Pleckstrin homology domain PH_9 PF15410.6 OAP63100.1 - 4.5e-09 36.7 2.1 0.0022 18.3 0.3 4.1 2 2 0 2 2 2 2 Pleckstrin homology domain PH_6 PF15406.6 OAP63100.1 - 1.6e-05 25.1 0.1 0.1 12.9 0.0 2.5 2 0 0 2 2 2 2 Pleckstrin homology domain PH_3 PF14593.6 OAP63100.1 - 2.2e-05 24.5 0.1 0.31 11.1 0.0 2.6 2 1 0 2 2 2 2 PH domain PH_13 PF16652.5 OAP63100.1 - 9.5e-05 22.3 0.8 0.44 10.3 0.0 2.4 2 0 0 2 2 2 2 Pleckstrin homology domain PH_8 PF15409.6 OAP63100.1 - 0.00079 19.7 0.4 0.31 11.3 0.0 2.3 2 0 0 2 2 2 2 Pleckstrin homology domain Mcp5_PH PF12814.7 OAP63100.1 - 0.0047 17.0 1.0 0.0079 16.3 0.2 1.7 2 0 0 2 2 2 1 Meiotic cell cortex C-terminal pleckstrin homology PH_2 PF08458.10 OAP63100.1 - 0.05 14.0 0.1 2.1 8.8 0.0 2.6 2 1 0 2 2 2 0 Plant pleckstrin homology-like region PH_12 PF16457.5 OAP63100.1 - 0.061 13.9 0.0 2.7 8.5 0.0 2.5 2 0 0 2 2 2 0 Pleckstrin homology domain Glyco_transf_15 PF01793.16 OAP63101.1 - 5.1e-96 321.8 11.9 1.8e-95 320.0 11.9 1.7 1 1 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase SPT6_acidic PF14632.6 OAP63102.1 - 0.48 11.0 3.7 0.55 10.9 0.0 2.7 3 0 0 3 3 3 0 Acidic N-terminal SPT6 Chs7 PF12271.8 OAP63103.1 - 1.8e-122 408.2 15.4 2.1e-122 408.0 15.4 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone DUF3382 PF11862.8 OAP63103.1 - 0.21 11.9 7.3 0.07 13.4 2.5 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF3382) DUF4282 PF14110.6 OAP63103.1 - 0.84 10.4 21.7 0.08 13.7 3.7 3.7 3 1 0 3 3 3 0 Domain of unknown function (DUF4282) Lactamase_B_2 PF12706.7 OAP63104.1 - 9.2e-18 64.5 3.3 1.9e-17 63.4 3.2 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 OAP63104.1 - 9e-14 51.7 1.9 2e-13 50.6 1.9 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 OAP63104.1 - 0.37 10.7 10.7 1.8 8.5 8.0 2.8 1 1 1 2 2 2 0 Metallo-beta-lactamase superfamily Cyclin PF08613.11 OAP63105.1 - 5.1e-14 53.0 0.0 7.7e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 OAP63105.1 - 0.004 16.9 0.0 0.0059 16.4 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Abhydrolase_6 PF12697.7 OAP63106.1 - 8e-05 23.3 6.0 0.0002 22.0 6.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 OAP63106.1 - 0.00066 19.5 0.0 0.0012 18.6 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.14 OAP63106.1 - 0.006 16.1 0.0 0.014 15.0 0.0 1.5 2 0 0 2 2 2 1 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 OAP63106.1 - 0.031 13.5 0.0 0.058 12.6 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OAP63106.1 - 0.12 12.0 0.2 2.5 7.7 0.0 2.7 3 0 0 3 3 3 0 alpha/beta hydrolase fold 4HBT_3 PF13622.6 OAP63108.1 - 1.7e-30 107.1 3.7 2.5e-30 106.6 3.7 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 OAP63108.1 - 7.1e-07 29.1 0.4 0.029 14.2 0.1 2.5 2 1 0 2 2 2 2 Acyl-CoA thioesterase Acetyltransf_10 PF13673.7 OAP63109.1 - 1.1e-08 35.1 0.0 2e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OAP63109.1 - 4.7e-08 33.4 0.0 1.4e-07 31.8 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAP63109.1 - 3.4e-07 30.5 0.0 7.5e-07 29.4 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 OAP63109.1 - 0.00062 19.7 0.0 0.00096 19.1 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 OAP63109.1 - 0.0011 19.1 0.0 0.91 9.6 0.0 2.4 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 OAP63109.1 - 0.0051 16.9 0.0 0.008 16.3 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase ADH_N PF08240.12 OAP63110.1 - 8.2e-26 90.0 2.6 1.3e-25 89.4 2.6 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAP63110.1 - 2.8e-16 59.7 0.0 9.1e-16 58.0 0.0 1.8 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAP63110.1 - 0.00076 20.5 0.0 0.0015 19.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ELFV_dehydrog PF00208.21 OAP63110.1 - 0.011 15.5 0.1 0.022 14.5 0.1 1.4 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ThiF PF00899.21 OAP63110.1 - 0.014 14.7 0.9 0.025 13.9 0.9 1.2 1 0 0 1 1 1 0 ThiF family 2-Hacid_dh_C PF02826.19 OAP63110.1 - 0.045 13.1 0.0 0.084 12.2 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Endomucin PF07010.12 OAP63111.1 - 0.41 10.6 35.2 0.15 12.0 32.8 1.4 2 0 0 2 2 2 0 Endomucin GREB1 PF15782.5 OAP63111.1 - 0.52 7.4 11.3 0.56 7.3 11.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Hamartin PF04388.12 OAP63111.1 - 0.84 8.2 14.6 0.91 8.1 14.6 1.1 1 0 0 1 1 1 0 Hamartin protein DUF572 PF04502.13 OAP63111.1 - 2 8.0 9.4 2.4 7.7 9.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Ndc1_Nup PF09531.10 OAP63111.1 - 2.6 6.6 13.1 3.4 6.2 13.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RIFIN PF02009.16 OAP63111.1 - 6.7 6.5 5.8 9.9 5.9 5.8 1.2 1 0 0 1 1 1 0 Rifin Nucleo_P87 PF07267.11 OAP63112.1 - 0.32 9.8 1.6 0.36 9.6 1.6 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 FAM176 PF14851.6 OAP63112.1 - 1.9 8.1 5.3 4.3 7.0 5.3 1.8 1 1 0 1 1 1 0 FAM176 family Arrestin_C PF02752.22 OAP63113.1 - 6.9e-14 52.5 0.0 6.6e-13 49.3 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Pro_isomerase PF00160.21 OAP63114.1 - 2.4e-43 148.1 0.0 2.8e-43 147.9 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SH3_1 PF00018.28 OAP63115.1 - 3.3e-05 23.4 0.0 6.8e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 OAP63115.1 - 0.041 13.7 0.0 0.098 12.5 0.0 1.7 1 0 0 1 1 1 0 Variant SH3 domain Pkinase PF00069.25 OAP63116.1 - 1e-40 139.8 0.0 1.6e-40 139.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP63116.1 - 8.4e-25 87.5 0.0 1.4e-18 67.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAP63116.1 - 0.033 13.0 0.0 0.077 11.8 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase DUF3827 PF12877.7 OAP63116.1 - 7 4.9 7.7 11 4.2 7.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Methyltransf_25 PF13649.6 OAP63117.1 - 0.00075 20.2 0.0 0.0024 18.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAP63117.1 - 0.0035 17.9 0.0 0.012 16.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAP63117.1 - 0.019 14.8 0.0 0.028 14.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain p450 PF00067.22 OAP63119.1 - 1.6e-62 211.8 0.0 7.5e-62 209.6 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 Tad PF13400.6 OAP63119.1 - 0.25 11.7 1.8 0.67 10.3 1.8 1.7 1 0 0 1 1 1 0 Putative Flp pilus-assembly TadE/G-like L_protein_N PF15518.6 OAP63120.1 - 0.04 13.8 0.0 0.084 12.7 0.0 1.4 1 0 0 1 1 1 0 L protein N-terminus Fungal_trans_2 PF11951.8 OAP63120.1 - 0.068 12.0 0.7 0.31 9.8 0.2 2.0 2 0 0 2 2 2 0 Fungal specific transcription factor domain AA_permease_2 PF13520.6 OAP63122.1 - 4.8e-47 160.8 60.1 5.9e-47 160.5 60.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAP63122.1 - 7.9e-31 107.2 51.4 1e-30 106.8 51.4 1.0 1 0 0 1 1 1 1 Amino acid permease DUF4227 PF14004.6 OAP63122.1 - 0.066 13.2 3.4 0.68 10.0 1.3 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4227) DUF1356 PF07092.12 OAP63122.1 - 0.29 10.4 1.3 0.8 8.9 1.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1356) TauD PF02668.16 OAP63123.1 - 1.5e-39 136.4 0.0 2.2e-39 135.9 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 OAP63123.1 - 5.3e-12 46.2 0.1 1.7e-11 44.6 0.1 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF971) CsiD PF08943.10 OAP63123.1 - 0.25 10.4 0.0 0.46 9.6 0.0 1.3 1 0 0 1 1 1 0 CsiD Macoilin PF09726.9 OAP63124.1 - 0.016 13.8 1.8 0.018 13.6 1.8 1.0 1 0 0 1 1 1 0 Macoilin family MCD_N PF17408.2 OAP63124.1 - 0.051 13.7 3.5 0.095 12.8 2.0 2.2 2 1 1 3 3 3 0 Malonyl-CoA decarboxylase N-terminal domain Fib_alpha PF08702.10 OAP63124.1 - 0.3 11.3 2.2 0.42 10.8 0.2 2.0 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Actin PF00022.19 OAP63125.1 - 1.3e-13 50.3 0.0 3.7e-10 39.0 0.0 3.1 3 0 0 3 3 3 3 Actin XPG_I PF00867.18 OAP63126.1 - 1.3e-25 89.5 0.0 2.4e-25 88.7 0.0 1.4 1 0 0 1 1 1 1 XPG I-region GEN1_C PF18380.1 OAP63126.1 - 4.9e-25 88.4 1.3 1.4e-24 87.0 1.3 1.9 1 0 0 1 1 1 1 Holliday junction resolvase Gen1 C-terminal domain XPG_I_2 PF12813.7 OAP63126.1 - 0.0027 17.2 0.0 0.0055 16.2 0.0 1.5 1 0 0 1 1 1 1 XPG domain containing FolB PF02152.18 OAP63127.1 - 4.5e-30 104.5 0.2 5.2e-19 68.8 1.7 2.1 2 0 0 2 2 2 2 Dihydroneopterin aldolase Pkinase PF00069.25 OAP63128.1 - 3.9e-62 210.0 0.0 5.3e-62 209.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP63128.1 - 4.8e-28 98.2 0.0 6.9e-28 97.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 OAP63128.1 - 0.0044 17.7 0.2 0.027 15.2 0.1 2.4 2 0 0 2 2 2 1 Protein kinase C terminal domain Pkinase_fungal PF17667.1 OAP63128.1 - 0.099 11.4 0.0 0.17 10.7 0.0 1.6 1 1 0 1 1 1 0 Fungal protein kinase F-box-like PF12937.7 OAP63129.1 - 0.048 13.6 1.0 0.38 10.7 0.1 2.8 3 0 0 3 3 3 0 F-box-like WSC PF01822.19 OAP63130.1 - 2.5e-06 27.6 5.2 1.1e-05 25.6 5.2 2.2 1 0 0 1 1 1 1 WSC domain FlgH PF02107.16 OAP63130.1 - 1.6 8.3 9.2 0.083 12.5 2.6 2.1 2 0 0 2 2 2 0 Flagellar L-ring protein DUF2124 PF09897.9 OAP63131.1 - 0.14 12.1 0.9 14 5.6 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2124) PAN_1 PF00024.26 OAP63133.1 - 0.0004 20.3 0.2 0.0027 17.6 0.0 2.4 2 0 0 2 2 2 1 PAN domain Glyco_hydro_16 PF00722.21 OAP63133.1 - 0.0016 17.9 1.2 0.002 17.6 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 MFS_1 PF07690.16 OAP63134.1 - 1.2e-29 103.4 39.4 4e-26 91.8 32.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAP63134.1 - 1.6 7.5 29.6 0.24 10.2 9.1 3.2 2 2 1 3 3 3 0 Sugar (and other) transporter DUF2158 PF09926.9 OAP63135.1 - 0.16 11.7 0.2 0.57 10.0 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized small protein (DUF2158) HMG_box PF00505.19 OAP63136.1 - 1.2e-24 86.5 1.9 2.2e-24 85.7 1.9 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 OAP63136.1 - 3.3e-18 66.0 2.5 6.1e-18 65.2 2.5 1.4 1 0 0 1 1 1 1 HMG-box domain Ccdc124 PF06244.12 OAP63136.1 - 0.0025 18.3 0.4 0.0025 18.3 0.4 2.3 1 1 1 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 HMG_box_5 PF14887.6 OAP63136.1 - 0.0065 16.4 0.7 0.017 15.1 0.7 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box 5 CHDNT PF08073.12 OAP63136.1 - 0.028 14.4 0.0 0.059 13.3 0.0 1.5 1 0 0 1 1 1 0 CHDNT (NUC034) domain YABBY PF04690.13 OAP63136.1 - 0.09 13.3 3.0 0.072 13.6 1.8 1.4 1 1 0 1 1 1 0 YABBY protein TPPII_N PF12583.8 OAP63136.1 - 0.11 13.1 4.7 0.16 12.6 4.7 1.3 1 0 0 1 1 1 0 Tripeptidyl peptidase II N terminal ATG11 PF10377.9 OAP63137.1 - 1.2e-46 157.9 0.0 1.2e-46 157.9 0.0 4.0 4 0 0 4 4 4 1 Autophagy-related protein 11 APG17 PF04108.12 OAP63137.1 - 1.2e-05 24.6 11.8 3.9e-05 22.9 4.0 6.0 3 2 2 5 5 5 2 Autophagy protein Apg17 Fez1 PF06818.15 OAP63137.1 - 0.0031 18.0 18.0 0.0031 18.0 18.0 5.9 3 2 2 5 5 5 1 Fez1 TPR_MLP1_2 PF07926.12 OAP63137.1 - 0.0073 16.4 15.5 0.0073 16.4 15.5 9.5 6 3 2 9 9 9 1 TPR/MLP1/MLP2-like protein DUF1319 PF07028.11 OAP63137.1 - 0.022 15.0 0.2 0.022 15.0 0.2 6.2 6 1 0 6 6 6 0 Protein of unknown function (DUF1319) Sas6_CC PF18594.1 OAP63137.1 - 4.1 7.3 8.3 7.7 6.4 0.1 4.4 3 0 0 3 3 3 0 Sas6/XLF/XRCC4 coiled-coil domain DUF3445 PF11927.8 OAP63138.1 - 5.4e-76 255.2 0.0 6.6e-76 254.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Homoserine_dh PF00742.19 OAP63139.1 - 2.2e-52 177.5 0.0 2.9e-52 177.1 0.0 1.1 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 OAP63139.1 - 3.9e-14 53.3 0.0 7.9e-14 52.3 0.0 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain NPDC1 PF06809.11 OAP63141.1 - 0.0066 15.6 0.2 0.0086 15.2 0.2 1.1 1 0 0 1 1 1 1 Neural proliferation differentiation control-1 protein (NPDC1) DUF1180 PF06679.12 OAP63141.1 - 0.0077 16.7 2.2 0.015 15.7 2.2 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1180) DUF4448 PF14610.6 OAP63141.1 - 0.027 14.2 0.0 0.034 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) CD34_antigen PF06365.12 OAP63141.1 - 0.042 13.4 0.0 0.06 12.9 0.0 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family TMEM154 PF15102.6 OAP63141.1 - 0.053 13.4 0.0 0.085 12.8 0.0 1.6 1 1 0 1 1 1 0 TMEM154 protein family DUF2207 PF09972.9 OAP63141.1 - 0.079 11.7 0.0 0.092 11.5 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) AJAP1_PANP_C PF15298.6 OAP63141.1 - 0.082 13.1 0.7 0.12 12.6 0.7 1.2 1 0 0 1 1 1 0 AJAP1/PANP C-terminus EphA2_TM PF14575.6 OAP63141.1 - 0.087 13.7 0.0 0.13 13.2 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain PAP_PilO PF06864.12 OAP63141.1 - 0.19 10.5 0.0 0.25 10.1 0.0 1.1 1 0 0 1 1 1 0 Pilin accessory protein (PilO) DUF4215 PF13948.6 OAP63142.1 - 0.00017 21.9 3.8 0.00017 21.9 3.8 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4215) DUF5470 PF17564.2 OAP63142.1 - 0.058 13.6 0.2 0.058 13.6 0.2 3.7 2 1 1 3 3 3 0 Family of unknown function (DUF5470) MAD PF05557.13 OAP63144.1 - 3.4e-68 230.6 66.0 7.2e-68 229.5 66.1 1.4 1 1 0 1 1 1 1 Mitotic checkpoint protein DUF1664 PF07889.12 OAP63144.1 - 0.0095 16.0 4.1 0.0095 16.0 4.1 5.7 4 2 1 5 5 5 1 Protein of unknown function (DUF1664) Fungal_trans_2 PF11951.8 OAP63145.1 - 0.044 12.6 1.5 0.12 11.2 0.0 2.3 3 0 0 3 3 3 0 Fungal specific transcription factor domain zf-C2H2 PF00096.26 OAP63149.1 - 1.9e-09 37.5 15.8 0.00012 22.4 1.4 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAP63149.1 - 2.2e-05 24.9 11.0 0.022 15.6 1.1 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OAP63149.1 - 0.075 13.5 6.5 14 6.3 1.1 3.7 3 0 0 3 3 3 0 Zinc-finger double domain zf-BED PF02892.15 OAP63149.1 - 0.28 11.3 2.0 0.65 10.1 2.0 1.6 1 0 0 1 1 1 0 BED zinc finger zf-Di19 PF05605.12 OAP63149.1 - 2.5 8.5 8.0 0.68 10.3 1.5 2.5 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding CENP-T_C PF15511.6 OAP63150.1 - 8e-09 35.6 0.1 9.7e-09 35.3 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 OAP63150.1 - 2.4e-05 24.7 0.1 2.8e-05 24.5 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 OAP63150.1 - 7.2e-05 22.9 0.1 0.0001 22.4 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 OAP63150.1 - 0.0002 21.6 0.1 0.00035 20.8 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 OAP63150.1 - 0.0004 20.7 0.1 0.00056 20.2 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 OAP63150.1 - 0.0085 16.2 0.0 0.01 15.9 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 OAP63150.1 - 0.031 14.3 0.0 0.037 14.0 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 OAP63150.1 - 0.052 13.3 0.2 0.064 13.0 0.2 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) HIGH_NTase1_ass PF16581.5 OAP63150.1 - 0.11 12.5 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region Histone PF00125.24 OAP63151.1 - 4e-52 176.0 2.5 4.5e-52 175.9 2.5 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 OAP63151.1 - 6e-06 26.6 0.0 9e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein PAF PF15715.5 OAP63151.1 - 4e-05 24.2 1.2 4.7e-05 24.0 1.2 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-T_C PF15511.6 OAP63151.1 - 4.3e-05 23.6 0.4 7.4e-05 22.8 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 OAP63151.1 - 0.0038 17.5 0.4 0.0065 16.7 0.0 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 OAP63151.1 - 0.026 14.6 0.2 0.042 13.9 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Mpv17_PMP22 PF04117.12 OAP63152.1 - 4.6e-14 52.4 0.8 1e-13 51.3 0.8 1.6 1 0 0 1 1 1 1 Mpv17 / PMP22 family Exo5 PF09810.9 OAP63153.1 - 7.2e-133 443.6 0.0 2.2e-132 442.0 0.0 1.7 2 0 0 2 2 2 1 Exonuclease V - a 5' deoxyribonuclease PDDEXK_1 PF12705.7 OAP63153.1 - 0.00022 21.2 5.0 0.00027 20.9 0.1 3.1 3 1 0 3 3 3 1 PD-(D/E)XK nuclease superfamily GPCR_chapero_1 PF11904.8 OAP63153.1 - 0.063 12.7 2.0 0.065 12.7 0.2 1.9 2 0 0 2 2 2 0 GPCR-chaperone DUF3799 PF12684.7 OAP63153.1 - 0.14 11.9 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 PDDEXK-like domain of unknown function (DUF3799) DUF3445 PF11927.8 OAP63154.1 - 1.6e-79 266.7 0.0 2.6e-79 266.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) ApoO PF09769.9 OAP63154.1 - 0.02 14.9 0.1 0.043 13.8 0.1 1.5 1 0 0 1 1 1 0 Apolipoprotein O Apolipoprotein PF01442.18 OAP63154.1 - 0.03 14.2 0.8 0.076 12.9 0.7 1.7 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain Syntaxin_2 PF14523.6 OAP63154.1 - 0.13 12.7 0.6 11 6.5 1.7 2.8 2 1 0 2 2 2 0 Syntaxin-like protein Glyco_transf_22 PF03901.17 OAP63155.1 - 7.8e-88 295.5 20.2 9e-88 295.3 20.2 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family DUF4646 PF15496.6 OAP63157.1 - 0.09 13.4 0.0 0.17 12.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4646) Keratin_2_head PF16208.5 OAP63157.1 - 8.9 6.4 43.1 1.1 9.3 24.7 2.6 2 0 0 2 2 2 0 Keratin type II head EHN PF06441.12 OAP63158.1 - 2.4e-28 98.6 0.3 4.9e-28 97.7 0.3 1.5 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 OAP63158.1 - 2.4e-08 33.9 0.0 4.7e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAP63158.1 - 0.016 15.8 0.4 0.03 14.9 0.4 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family FPN1 PF06963.12 OAP63159.1 - 1.7e-121 405.9 18.7 2.1e-121 405.5 18.7 1.0 1 0 0 1 1 1 1 Ferroportin1 (FPN1) KH_6 PF15985.5 OAP63159.1 - 0.044 14.1 0.3 0.33 11.3 0.0 2.6 3 0 0 3 3 3 0 KH domain Gar1 PF04410.14 OAP63160.1 - 1.6e-44 151.4 1.0 1.6e-44 151.4 1.0 1.6 2 0 0 2 2 2 1 Gar1/Naf1 RNA binding region LCE PF14672.6 OAP63160.1 - 0.066 13.8 0.3 0.066 13.8 0.3 3.1 3 1 0 3 3 3 0 Late cornified envelope YL1 PF05764.13 OAP63160.1 - 2.2 8.3 13.2 8.8 6.4 6.9 2.5 2 0 0 2 2 2 0 YL1 nuclear protein EPSP_synthase PF00275.20 OAP63161.1 - 1.8e-130 435.4 0.0 4.8e-130 434.0 0.0 1.7 2 0 0 2 2 2 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.20 OAP63161.1 - 6e-98 327.2 0.0 9.9e-98 326.5 0.0 1.3 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.15 OAP63161.1 - 2.8e-56 191.3 0.0 1.2e-55 189.3 0.0 2.1 3 0 0 3 3 3 1 Type I 3-dehydroquinase SKI PF01202.22 OAP63161.1 - 3.4e-37 128.0 0.9 1.2e-36 126.3 0.0 2.3 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.11 OAP63161.1 - 8.2e-25 86.9 0.0 1.9e-24 85.7 0.0 1.7 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Fe-ADH_2 PF13685.6 OAP63161.1 - 4.4e-09 36.4 0.0 8.9e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase MAF_flag10 PF01973.18 OAP63161.1 - 0.0051 16.5 0.0 0.014 15.1 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function DUF115 SDH_C PF18317.1 OAP63161.1 - 0.0075 16.0 0.2 0.13 12.0 0.1 2.5 2 0 0 2 2 2 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 OAP63161.1 - 0.017 15.2 0.0 0.04 14.0 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase AAA_33 PF13671.6 OAP63161.1 - 0.049 13.8 0.0 0.23 11.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 OAP63161.1 - 0.11 12.8 0.1 4.1 7.8 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_24 PF13479.6 OAP63161.1 - 0.14 11.8 0.0 0.49 10.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain MOSC PF03473.17 OAP63162.1 - 6.4e-23 81.2 0.0 1.7e-22 79.9 0.0 1.7 2 0 0 2 2 2 1 MOSC domain MOSC_N PF03476.16 OAP63162.1 - 5.7e-15 55.3 0.0 1.2e-14 54.2 0.0 1.5 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain Epimerase PF01370.21 OAP63163.1 - 8e-12 45.1 0.0 2.7e-11 43.4 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 OAP63163.1 - 3.8e-06 26.9 0.4 5.5e-06 26.4 0.4 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 OAP63163.1 - 0.00011 21.3 0.0 0.00084 18.4 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Shikimate_DH PF01488.20 OAP63163.1 - 0.00055 20.0 0.1 0.00089 19.3 0.1 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NmrA PF05368.13 OAP63163.1 - 0.00076 19.1 0.1 0.0011 18.5 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family TrkA_N PF02254.18 OAP63163.1 - 0.00078 19.7 0.3 0.0064 16.7 0.3 2.3 3 0 0 3 3 2 1 TrkA-N domain AlaDh_PNT_C PF01262.21 OAP63163.1 - 0.0011 18.3 0.3 0.0018 17.6 0.3 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain GDP_Man_Dehyd PF16363.5 OAP63163.1 - 0.0028 17.1 0.0 0.13 11.6 0.0 2.3 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase ADH_zinc_N PF00107.26 OAP63163.1 - 0.0041 17.1 0.1 0.008 16.2 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_2 PF03446.15 OAP63163.1 - 0.005 17.0 0.1 0.0079 16.4 0.1 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.16 OAP63163.1 - 0.01 15.5 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 OAP63163.1 - 0.035 14.0 0.2 0.052 13.4 0.2 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 OAP63163.1 - 0.049 14.2 0.1 0.15 12.7 0.1 1.9 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 OAP63163.1 - 0.13 11.6 0.1 0.19 11.0 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Sugar_tr PF00083.24 OAP63164.1 - 5.6e-73 246.3 20.2 6.5e-73 246.1 20.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP63164.1 - 8.6e-13 47.9 31.4 7.8e-09 34.9 29.8 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Lipase_GDSL_2 PF13472.6 OAP63165.1 - 3.4e-22 79.7 0.1 3.4e-21 76.4 0.1 2.0 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 OAP63165.1 - 1.8e-17 64.0 0.0 2.5e-17 63.5 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Fungal_trans PF04082.18 OAP63166.1 - 1e-23 83.7 0.0 2.2e-23 82.7 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain MR_MLE_C PF13378.6 OAP63167.1 - 2.3e-55 187.5 0.0 3.8e-55 186.8 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 OAP63167.1 - 2.3e-05 24.6 0.0 5e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MAAL_C PF07476.11 OAP63167.1 - 0.00012 21.3 0.0 0.00018 20.7 0.0 1.2 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus Glyco_hyd_65N_2 PF14498.6 OAP63168.1 - 4.5e-37 128.2 0.0 6.9e-37 127.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain COX2-transmemb PF09125.10 OAP63169.1 - 1.1 9.1 5.3 0.28 11.0 0.4 2.4 2 1 1 3 3 3 0 Cytochrome C oxidase subunit II, transmembrane Ribosomal_S2 PF00318.20 OAP63170.1 - 1e-27 96.8 0.1 2.2e-15 56.5 0.1 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 OAP63170.1 - 0.0001 23.6 9.9 0.0002 22.7 9.9 1.5 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus Ribosomal_S15 PF00312.22 OAP63171.1 - 3.5e-25 88.0 0.5 1e-24 86.5 0.2 2.0 2 0 0 2 2 2 1 Ribosomal protein S15 adh_short_C2 PF13561.6 OAP63172.1 - 3.4e-52 177.4 0.0 4.2e-52 177.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP63172.1 - 1.9e-40 138.5 0.1 2.3e-40 138.1 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAP63172.1 - 7.4e-08 32.5 0.0 3e-07 30.5 0.0 1.8 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 OAP63172.1 - 5.6e-06 26.0 0.1 2.9e-05 23.7 0.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family CAT_RBD PF03123.15 OAP63172.1 - 0.0032 17.4 0.1 3.3 7.7 0.1 2.3 2 0 0 2 2 2 2 CAT RNA binding domain Methyltransf_25 PF13649.6 OAP63172.1 - 0.029 15.1 0.0 0.057 14.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain THF_DHG_CYH_C PF02882.19 OAP63172.1 - 0.041 13.2 0.3 0.2 11.0 0.1 2.0 1 1 1 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain RmlD_sub_bind PF04321.17 OAP63172.1 - 0.051 12.7 0.0 0.08 12.0 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain TrkA_N PF02254.18 OAP63172.1 - 0.083 13.2 0.1 0.21 11.8 0.0 1.7 2 0 0 2 2 2 0 TrkA-N domain 2-Hacid_dh_C PF02826.19 OAP63172.1 - 0.16 11.3 0.1 0.35 10.2 0.1 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Hydrolase_4 PF12146.8 OAP63173.1 - 3.4e-12 46.1 0.0 1.1e-11 44.5 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OAP63173.1 - 2.4e-11 44.7 0.3 3.5e-11 44.1 0.3 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAP63173.1 - 4.4e-09 36.4 0.0 5.7e-08 32.7 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold NmrA PF05368.13 OAP63174.1 - 1.8e-16 60.4 0.0 2.4e-16 60.0 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAP63174.1 - 4.9e-12 46.1 0.3 8.5e-12 45.3 0.3 1.5 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAP63174.1 - 5.5e-05 22.7 0.2 7.9e-05 22.2 0.2 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.20 OAP63174.1 - 0.00034 20.7 0.1 0.00056 20.0 0.1 1.3 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.24 OAP63174.1 - 0.0018 18.7 0.0 0.0032 17.9 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 OAP63174.1 - 0.0024 17.9 0.0 0.0039 17.3 0.0 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 OAP63174.1 - 0.008 16.7 0.8 0.015 15.8 0.2 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 3Beta_HSD PF01073.19 OAP63174.1 - 0.017 14.1 0.0 0.029 13.4 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 OAP63174.1 - 0.018 14.9 0.1 0.03 14.3 0.1 1.3 1 0 0 1 1 1 0 KR domain RmlD_sub_bind PF04321.17 OAP63174.1 - 0.049 12.7 0.3 0.079 12.1 0.3 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain TrkA_N PF02254.18 OAP63174.1 - 0.067 13.5 0.2 0.13 12.5 0.2 1.5 1 0 0 1 1 1 0 TrkA-N domain Ldh_1_N PF00056.23 OAP63174.1 - 0.081 13.0 0.4 0.16 12.0 0.4 1.4 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 OAP63174.1 - 0.098 13.5 0.0 0.17 12.7 0.0 1.3 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold GDP_Man_Dehyd PF16363.5 OAP63174.1 - 0.11 11.8 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Pigment_DH PF06324.11 OAP63174.1 - 0.44 10.7 1.8 1.5 9.0 0.1 2.4 2 0 0 2 2 2 0 Pigment-dispersing hormone (PDH) DUF2196 PF09962.9 OAP63176.1 - 1.2e-23 82.9 3.7 2.4e-23 81.9 3.7 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2196) TFIIA PF03153.13 OAP63176.1 - 1.6 8.7 29.4 1.8 8.4 29.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Neur_chan_memb PF02932.16 OAP63176.1 - 4.2 7.3 7.3 5.9 6.9 7.3 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SOG2 PF10428.9 OAP63176.1 - 6.6 5.8 18.1 7.7 5.6 18.1 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Ras PF00071.22 OAP63177.1 - 1.5e-10 40.9 0.0 2e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 Ras family CYSTM PF12734.7 OAP63178.1 - 6.5e-11 42.4 6.2 6.5e-11 42.4 6.2 4.2 3 1 0 3 3 3 1 Cysteine-rich TM module stress tolerance Pkinase PF00069.25 OAP63179.1 - 1.1e-53 182.3 0.0 1.4e-53 182.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP63179.1 - 4.9e-33 114.5 0.0 5.9e-33 114.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAP63179.1 - 1.7e-05 24.3 0.0 0.00011 21.7 0.0 1.9 1 1 1 2 2 2 1 Kinase-like APH PF01636.23 OAP63179.1 - 9.8e-05 22.4 0.0 0.00075 19.5 0.0 1.8 1 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 OAP63179.1 - 0.0056 16.0 0.1 0.0087 15.4 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OAP63179.1 - 0.075 12.0 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Choline_kinase PF01633.20 OAP63179.1 - 0.14 11.7 0.1 0.22 11.1 0.1 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pox_ser-thr_kin PF05445.11 OAP63179.1 - 0.16 10.9 0.0 0.25 10.3 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase LIP PF03583.14 OAP63180.1 - 1.6e-62 211.5 0.1 2.2e-62 211.0 0.1 1.1 1 0 0 1 1 1 1 Secretory lipase Amidohydro_1 PF01979.20 OAP63181.1 - 3.6e-43 148.2 0.2 4.2e-43 148.0 0.2 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 OAP63181.1 - 3.2e-15 56.6 0.4 1.1e-11 44.9 0.1 2.1 2 0 0 2 2 2 2 Amidohydrolase family DUF1275 PF06912.11 OAP63182.1 - 2e-46 158.4 7.7 2.3e-46 158.1 7.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) RELT PF12606.8 OAP63182.1 - 0.13 11.3 0.4 0.41 9.7 0.4 1.9 1 0 0 1 1 1 0 Tumour necrosis factor receptor superfamily member 19 DUF4191 PF13829.6 OAP63182.1 - 0.19 11.0 0.2 1.6 8.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) PGM_PMM_I PF02878.16 OAP63183.1 - 9.9e-31 106.3 0.0 1.5e-30 105.7 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 OAP63183.1 - 5.5e-24 84.5 0.0 9.4e-24 83.8 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 OAP63183.1 - 4e-15 56.3 0.0 8.3e-15 55.3 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 OAP63183.1 - 8.7e-07 29.0 0.0 2e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain RNase_T PF00929.24 OAP63185.1 - 4.7e-15 56.5 0.0 5.6e-15 56.3 0.0 1.1 1 0 0 1 1 1 1 Exonuclease SWIB PF02201.18 OAP63186.1 - 3.6e-21 74.8 0.0 8.8e-21 73.6 0.0 1.7 1 0 0 1 1 1 1 SWIB/MDM2 domain Sulfatase_C PF14707.6 OAP63186.1 - 3.9 8.2 6.2 0.49 11.1 0.2 2.5 3 0 0 3 3 3 0 C-terminal region of aryl-sulfatase His_Phos_1 PF00300.22 OAP63187.1 - 3.7e-28 98.5 0.7 2.3e-27 95.9 0.1 2.3 2 1 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) Dor1 PF04124.12 OAP63188.1 - 4e-45 154.0 0.4 6.1e-33 113.9 0.8 2.3 2 0 0 2 2 2 2 Dor1-like family Spt5_N PF11942.8 OAP63188.1 - 0.28 12.2 10.4 0.83 10.7 10.4 1.8 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal Nop14 PF04147.12 OAP63188.1 - 3.8 5.6 13.2 1.8 6.7 8.7 2.1 2 0 0 2 2 2 0 Nop14-like family SHS2_Rpb7-N PF03876.17 OAP63190.1 - 1.2e-11 44.8 0.0 1.7e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 OAP63190.1 - 1.1e-05 25.7 0.0 3.1e-05 24.2 0.0 1.7 2 1 0 2 2 2 1 S1 RNA binding domain Fungal_trans PF04082.18 OAP63192.1 - 3.6e-14 52.4 0.1 3.6e-14 52.4 0.1 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP63192.1 - 7.3e-07 29.2 12.2 1.2e-06 28.5 12.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HSBP1 PF06825.12 OAP63192.1 - 0.094 12.6 0.1 0.18 11.7 0.1 1.4 1 0 0 1 1 1 0 Heat shock factor binding protein 1 Na_Ca_ex PF01699.24 OAP63193.1 - 9e-25 87.4 26.0 2.8e-12 46.9 10.7 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein PIP5K PF01504.18 OAP63194.1 - 1.8e-96 322.6 0.0 5e-96 321.1 0.0 1.8 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase AUDH_Cupin PF18637.1 OAP63194.1 - 0.17 11.9 0.0 0.44 10.6 0.0 1.6 1 0 0 1 1 1 0 Aldos-2-ulose dehydratase/isomerase (AUDH) Cupin domain Pmp3 PF01679.17 OAP63195.1 - 1.3e-22 79.7 8.3 1.5e-22 79.5 8.3 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator DUF4191 PF13829.6 OAP63195.1 - 0.14 11.5 0.1 0.15 11.4 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) EMG1 PF03587.14 OAP63196.1 - 4.5e-80 267.9 0.0 5.3e-80 267.7 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase RP854 PF17460.2 OAP63196.1 - 0.014 15.2 0.1 0.025 14.3 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein RP854 Glyoxalase PF00903.25 OAP63197.1 - 0.081 13.1 0.0 0.081 13.1 0.0 2.9 2 1 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Ada_Zn_binding PF02805.16 OAP63198.1 - 2.8e-28 97.7 5.3 5.7e-28 96.7 5.3 1.5 1 0 0 1 1 1 1 Metal binding domain of Ada HTH_AraC PF00165.23 OAP63198.1 - 0.00025 21.0 0.0 0.00051 20.1 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_18 PF12833.7 OAP63198.1 - 0.00042 20.5 0.0 0.00086 19.5 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain GST_C_6 PF17171.4 OAP63198.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Spt20 PF12090.8 OAP63198.1 - 8.1 6.0 13.0 15 5.1 13.0 1.3 1 0 0 1 1 1 0 Spt20 family Glyco_transf_90 PF05686.12 OAP63199.1 - 6.4e-13 48.4 0.2 4.8e-09 35.6 0.1 3.1 2 1 0 2 2 2 2 Glycosyl transferase family 90 GNAT_acetyltr_2 PF13718.6 OAP63200.1 - 3.8e-98 327.4 0.0 6.9e-98 326.6 0.0 1.5 1 0 0 1 1 1 1 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.6 OAP63200.1 - 3.5e-77 259.3 0.0 5.8e-77 258.6 0.0 1.4 1 0 0 1 1 1 1 Possible tRNA binding domain Helicase_RecD PF05127.14 OAP63200.1 - 1.2e-65 220.7 0.0 4.9e-65 218.7 0.0 1.9 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.11 OAP63200.1 - 4e-34 116.4 0.0 1.1e-33 115.0 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) AAA_30 PF13604.6 OAP63200.1 - 0.00034 20.4 0.2 0.037 13.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain GHMP_kinases_N PF00288.26 OAP63200.1 - 0.15 12.3 0.1 0.42 10.9 0.1 1.7 1 0 0 1 1 1 0 GHMP kinases N terminal domain FlhC PF05280.11 OAP63201.1 - 0.038 13.7 0.4 0.068 12.9 0.4 1.3 1 0 0 1 1 1 0 Flagellar transcriptional activator (FlhC) Thioredoxin PF00085.20 OAP63202.1 - 3.4e-29 100.9 0.0 8.6e-25 86.7 0.0 2.9 3 0 0 3 3 3 2 Thioredoxin TraF PF13728.6 OAP63202.1 - 1.5e-05 25.0 2.3 0.015 15.1 0.0 3.6 3 0 0 3 3 3 1 F plasmid transfer operon protein Thioredoxin_6 PF13848.6 OAP63202.1 - 9.6e-05 22.4 0.0 0.018 15.0 0.0 2.9 3 0 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_2 PF13098.6 OAP63202.1 - 0.0005 20.5 0.0 0.071 13.6 0.0 2.7 2 0 0 2 2 2 1 Thioredoxin-like domain OST3_OST6 PF04756.13 OAP63202.1 - 0.0061 15.9 0.0 0.014 14.8 0.0 1.5 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 OAP63202.1 - 0.015 15.5 0.0 0.037 14.2 0.0 1.7 1 0 0 1 1 1 0 Thioredoxin-like AhpC-TSA PF00578.21 OAP63202.1 - 0.022 14.7 0.0 0.095 12.6 0.0 2.0 3 0 0 3 3 3 0 AhpC/TSA family Thioredoxin_8 PF13905.6 OAP63202.1 - 0.025 14.9 0.0 36 4.8 0.0 3.7 3 1 1 4 4 4 0 Thioredoxin-like Zn_clus PF00172.18 OAP63203.1 - 0.00016 21.7 5.0 0.00016 21.7 5.0 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3752 PF12572.8 OAP63204.1 - 5.9e-32 111.3 12.8 2.8e-21 76.6 3.6 2.9 3 1 1 4 4 4 2 Protein of unknown function (DUF3752) Dynamitin PF04912.14 OAP63204.1 - 0.0045 16.4 0.1 0.0065 15.8 0.1 1.2 1 0 0 1 1 1 1 Dynamitin Cwf_Cwc_15 PF04889.12 OAP63204.1 - 7.2 6.3 11.8 0.99 9.1 4.2 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein ALMT PF11744.8 OAP63205.1 - 1 8.1 2.5 1.5 7.6 2.5 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Apt1 PF10351.9 OAP63205.1 - 3.3 6.5 7.4 5.1 5.8 7.4 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain Pro_isomerase PF00160.21 OAP63206.1 - 3.4e-45 154.2 0.1 3.9e-45 154.0 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 3Beta_HSD PF01073.19 OAP63208.1 - 1.7e-09 37.1 0.0 2.6e-09 36.5 0.0 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 OAP63208.1 - 4.2e-09 36.2 0.1 1.3e-08 34.6 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 OAP63208.1 - 1.7e-07 31.3 0.0 2.5e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 OAP63208.1 - 1.6e-06 27.8 0.0 3.1e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 OAP63208.1 - 1.7e-05 24.1 0.0 0.0015 17.8 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein NmrA PF05368.13 OAP63208.1 - 0.00039 20.0 0.0 0.00072 19.2 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family FAD_binding_2 PF00890.24 OAP63209.1 - 9.7e-82 275.3 0.4 1.2e-81 275.0 0.4 1.1 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.28 OAP63209.1 - 5e-22 77.8 0.1 4.5e-20 71.6 0.0 3.2 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.24 OAP63209.1 - 1.2e-13 51.4 0.1 2e-13 50.7 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAP63209.1 - 3.7e-09 36.7 0.7 1.2e-07 31.8 0.2 3.1 2 1 1 3 3 3 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 OAP63209.1 - 1.2e-08 34.8 0.2 5.4e-08 32.6 0.2 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAP63209.1 - 5.5e-06 25.8 0.1 1.9e-05 24.1 0.1 2.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAP63209.1 - 7.1e-05 22.2 0.0 0.2 10.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAP63209.1 - 0.00013 20.9 2.3 0.00044 19.1 0.4 2.6 2 1 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 OAP63209.1 - 0.00051 19.2 1.3 0.16 11.1 0.5 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.17 OAP63209.1 - 0.0016 17.8 0.3 0.058 12.6 0.1 2.3 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 OAP63209.1 - 0.0037 16.6 0.1 0.0056 16.0 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 OAP63209.1 - 0.011 15.0 0.1 0.023 14.0 0.1 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Amino_oxidase PF01593.24 OAP63209.1 - 0.014 14.8 0.5 1.1 8.4 0.0 2.9 2 1 0 3 3 3 0 Flavin containing amine oxidoreductase APC_basic PF05956.11 OAP63209.1 - 0.061 12.8 1.3 0.089 12.2 1.3 1.1 1 0 0 1 1 1 0 APC basic domain Pyr_redox PF00070.27 OAP63209.1 - 0.068 13.7 0.7 5.3 7.7 0.3 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GDI PF00996.18 OAP63209.1 - 0.099 11.1 0.1 0.18 10.3 0.1 1.3 1 0 0 1 1 1 0 GDP dissociation inhibitor TFIIS_M PF07500.14 OAP63210.1 - 5.1e-29 101.0 0.4 1e-28 100.0 0.4 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 OAP63210.1 - 6.3e-19 67.5 5.4 1.1e-18 66.7 5.4 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 OAP63210.1 - 9.7e-12 44.7 0.1 2.4e-11 43.5 0.1 1.7 1 0 0 1 1 1 1 TFIIS helical bundle-like domain PSCyt2 PF07583.11 OAP63210.1 - 0.068 13.1 0.1 0.12 12.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1549) Cytochrom_NNT PF03264.14 OAP63210.1 - 0.41 10.3 6.4 0.66 9.7 6.4 1.3 1 0 0 1 1 1 0 NapC/NirT cytochrome c family, N-terminal region Cytochrome_C7 PF14522.6 OAP63210.1 - 0.86 9.6 8.8 2.3 8.3 8.9 1.7 1 1 0 1 1 1 0 Cytochrome c7 and related cytochrome c Acetyltransf_1 PF00583.25 OAP63211.1 - 0.00098 19.3 0.0 0.0023 18.1 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OAP63211.1 - 0.0012 19.2 0.0 0.0023 18.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OAP63211.1 - 0.0051 16.7 0.0 0.011 15.6 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 OAP63211.1 - 0.01 15.9 0.0 0.019 15.1 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase FR47 PF08445.10 OAP63211.1 - 0.018 15.0 0.0 0.03 14.3 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein PanZ PF12568.8 OAP63211.1 - 0.2 11.4 0.0 0.37 10.5 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ CorA PF01544.18 OAP63212.1 - 2.2e-05 23.9 0.1 8.4e-05 22.0 0.1 1.8 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Med9 PF07544.13 OAP63212.1 - 1.2 9.3 4.4 9.1 6.5 0.8 2.9 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 ANAPC_CDC26 PF10471.9 OAP63213.1 - 2.5e-10 41.0 0.5 1.3e-08 35.6 0.5 2.2 1 1 0 1 1 1 1 Anaphase-promoting complex APC subunit CDC26 VWA_2 PF13519.6 OAP63214.1 - 9.4e-21 74.5 0.0 2.7e-20 73.0 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 OAP63214.1 - 8.5e-08 32.6 0.1 1.3e-07 32.0 0.1 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.14 OAP63214.1 - 1.6e-05 24.9 0.0 2.4e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like Salt_tol_Pase PF09506.10 OAP63214.1 - 0.011 14.6 0.0 0.015 14.1 0.0 1.2 1 0 0 1 1 1 0 Glucosylglycerol-phosphate phosphatase (Salt_tol_Pase) UIM PF02809.20 OAP63214.1 - 0.014 15.2 2.1 0.041 13.8 2.1 1.8 1 0 0 1 1 1 0 Ubiquitin interaction motif Sybindin PF04099.12 OAP63215.1 - 1.7e-35 122.0 0.0 2.6e-35 121.4 0.0 1.3 1 0 0 1 1 1 1 Sybindin-like family HNH_2 PF13391.6 OAP63215.1 - 2.9e-14 53.0 0.1 1.1e-13 51.1 0.0 2.0 2 0 0 2 2 2 1 HNH endonuclease Sedlin_N PF04628.13 OAP63215.1 - 0.0098 16.0 0.0 0.018 15.2 0.0 1.4 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Fungal_trans PF04082.18 OAP63216.1 - 1.4e-09 37.4 0.4 1.4e-09 37.4 0.4 2.1 3 0 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP63216.1 - 1.5e-05 25.0 9.3 2.8e-05 24.2 9.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FeS_assembly_P PF01883.19 OAP63217.1 - 1.4e-07 31.6 0.0 3.5e-07 30.3 0.0 1.7 1 1 0 1 1 1 1 Iron-sulfur cluster assembly protein Sugar_tr PF00083.24 OAP63218.1 - 7.1e-19 68.0 25.0 5.7e-11 41.9 7.4 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter TMEM213 PF15192.6 OAP63218.1 - 1 9.3 4.4 4.9 7.2 1.5 2.4 2 0 0 2 2 2 0 TMEM213 family Presenilin PF01080.17 OAP63219.1 - 0.34 9.6 3.8 0.51 9.1 3.8 1.2 1 0 0 1 1 1 0 Presenilin Pkinase PF00069.25 OAP63220.1 - 1.7e-57 194.8 0.0 2.4e-57 194.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP63220.1 - 4.4e-40 137.6 0.0 6.7e-40 137.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAP63220.1 - 2.5e-05 23.2 0.2 0.00014 20.8 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 OAP63220.1 - 3.1e-05 23.4 0.0 5.6e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OAP63220.1 - 0.00047 19.6 0.1 0.00092 18.6 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OAP63220.1 - 0.0041 16.7 0.0 0.01 15.4 0.0 1.7 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 OAP63220.1 - 0.0083 16.1 0.1 0.0083 16.1 0.1 3.0 2 2 1 3 3 3 1 Phosphotransferase enzyme family FTA2 PF13095.6 OAP63220.1 - 0.082 12.5 0.0 0.16 11.6 0.0 1.6 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 KCT2 PF17818.1 OAP63220.1 - 0.79 9.8 4.6 3.1 7.9 0.1 3.3 2 1 0 2 2 2 0 Keratinocyte-associated gene product FlaF PF07309.11 OAP63220.1 - 1.2 9.1 3.9 3.5 7.7 0.0 2.7 2 0 0 2 2 2 0 Flagellar protein FlaF HA2 PF04408.23 OAP63221.1 - 1.3e-21 76.9 0.0 1.3e-21 76.9 0.0 3.2 4 0 0 4 4 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 OAP63221.1 - 2.7e-18 66.1 0.0 2e-17 63.3 0.0 2.3 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 OAP63221.1 - 9.3e-14 51.7 0.0 2.6e-13 50.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 OAP63221.1 - 3.9e-07 30.0 0.1 9.2e-07 28.8 0.1 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 OAP63221.1 - 3.4e-05 24.1 0.1 9.5e-05 22.7 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 OAP63221.1 - 0.00018 21.3 0.0 0.00045 20.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 OAP63221.1 - 0.00041 19.7 0.0 0.00098 18.5 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) SRP54 PF00448.22 OAP63221.1 - 0.00045 19.9 0.2 0.0013 18.4 0.2 1.8 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain T2SSE PF00437.20 OAP63221.1 - 0.00057 19.0 0.0 0.0016 17.6 0.1 1.7 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_19 PF13245.6 OAP63221.1 - 0.00089 19.6 0.2 0.0021 18.4 0.2 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 OAP63221.1 - 0.005 16.9 0.2 0.037 14.1 0.2 2.4 1 1 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.14 OAP63221.1 - 0.0084 16.1 0.1 0.017 15.1 0.1 1.5 1 0 0 1 1 1 1 Flavivirus DEAD domain ResIII PF04851.15 OAP63221.1 - 0.0085 16.1 0.1 4 7.4 0.0 2.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Microtub_bd PF16796.5 OAP63221.1 - 0.031 14.2 0.0 0.27 11.2 0.0 2.2 2 0 0 2 2 2 0 Microtubule binding ATPase PF06745.13 OAP63221.1 - 0.045 13.1 0.0 0.089 12.1 0.0 1.4 1 0 0 1 1 1 0 KaiC Zeta_toxin PF06414.12 OAP63221.1 - 0.07 12.4 0.2 0.26 10.5 0.1 2.0 1 1 1 2 2 2 0 Zeta toxin AAA_25 PF13481.6 OAP63221.1 - 0.073 12.6 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 OAP63221.1 - 0.11 12.1 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 OAP63221.1 - 0.12 12.8 0.0 0.33 11.3 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 OAP63221.1 - 0.12 12.3 2.1 1 9.2 0.3 2.9 3 0 0 3 3 3 0 NACHT domain AAA_24 PF13479.6 OAP63221.1 - 0.12 12.0 0.0 0.36 10.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 OAP63221.1 - 0.13 11.8 0.2 0.57 9.7 0.1 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Glug PF07581.12 OAP63221.1 - 0.17 12.3 0.0 0.46 11.0 0.0 1.7 1 0 0 1 1 1 0 The GLUG motif AAA_33 PF13671.6 OAP63221.1 - 0.2 11.8 0.1 0.2 11.8 0.1 2.6 3 1 0 3 3 2 0 AAA domain Prefoldin_2 PF01920.20 OAP63222.1 - 9e-24 83.5 9.6 1.1e-23 83.2 9.6 1.1 1 0 0 1 1 1 1 Prefoldin subunit SMC_ScpA PF02616.14 OAP63222.1 - 0.0073 16.2 2.0 0.0092 15.9 2.0 1.1 1 0 0 1 1 1 1 Segregation and condensation protein ScpA Spuma_A9PTase PF03539.14 OAP63222.1 - 0.01 16.0 2.0 0.014 15.6 0.2 1.8 1 1 1 2 2 2 0 Spumavirus aspartic protease (A9) Baculo_PEP_C PF04513.12 OAP63222.1 - 0.012 15.6 0.5 0.21 11.6 0.0 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Prefoldin PF02996.17 OAP63222.1 - 0.013 15.4 7.5 1.5 8.7 7.3 2.3 1 1 0 1 1 1 0 Prefoldin subunit CLZ PF16526.5 OAP63222.1 - 0.12 12.7 5.8 3.5 8.0 0.1 2.2 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels CC2-LZ PF16516.5 OAP63222.1 - 0.21 11.9 8.9 1.9 8.9 1.0 2.1 2 0 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Com_YlbF PF06133.11 OAP63222.1 - 0.26 11.9 9.4 0.36 11.4 1.4 2.1 2 0 0 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA DUF2205 PF10224.9 OAP63222.1 - 0.26 11.3 6.7 0.1 12.6 1.1 2.1 2 0 0 2 2 2 0 Short coiled-coil protein Spc24 PF08286.11 OAP63222.1 - 0.42 10.9 8.8 0.35 11.1 1.5 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 HAUS6_N PF14661.6 OAP63222.1 - 1.6 8.3 8.8 4.1 6.9 8.8 1.7 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF3450 PF11932.8 OAP63222.1 - 2.6 7.3 11.0 2.1 7.6 3.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Rho_Binding PF08912.11 OAP63222.1 - 4.2 8.3 13.8 3.1 8.7 3.6 2.3 2 0 0 2 2 2 0 Rho Binding Sulfate_transp PF00916.20 OAP63225.1 - 2.5e-74 250.3 12.5 3.5e-74 249.8 12.5 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 OAP63225.1 - 5.4e-06 26.0 0.0 0.00012 21.7 0.0 2.3 2 0 0 2 2 2 1 STAS domain Prok-E2_E PF14462.6 OAP63225.1 - 0.1 12.4 0.4 0.2 11.5 0.4 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family E MFS_MOT1 PF16983.5 OAP63225.1 - 0.5 10.8 18.4 0.038 14.4 6.4 3.0 2 1 0 2 2 2 0 Molybdate transporter of MFS superfamily Aldose_epim PF01263.20 OAP63227.1 - 9.3e-54 182.8 0.5 1.2e-53 182.4 0.5 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase Sds3 PF08598.11 OAP63228.1 - 8.4e-30 104.4 15.2 4.9e-29 101.9 15.2 2.0 1 1 0 1 1 1 1 Sds3-like PID_2 PF14719.6 OAP63228.1 - 2.5 7.9 4.9 0.3 10.9 0.5 1.7 2 0 0 2 2 2 0 Phosphotyrosine interaction domain (PTB/PID) Amidohydro_1 PF01979.20 OAP63229.1 - 4.2e-20 72.4 0.1 1e-19 71.1 0.1 1.7 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 OAP63229.1 - 3.8e-12 46.4 5.9 1.2e-08 34.9 0.3 3.0 1 1 1 2 2 2 2 Amidohydrolase family Methyltransf_2 PF00891.18 OAP63231.1 - 7.8e-20 71.1 0.0 1.2e-19 70.4 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain AlaDh_PNT_C PF01262.21 OAP63231.1 - 0.012 14.9 0.2 0.021 14.1 0.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Gpr1_Fun34_YaaH PF01184.19 OAP63233.1 - 1.2e-30 106.7 20.0 1.6e-30 106.3 20.0 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Thioredoxin_4 PF13462.6 OAP63237.1 - 1.2e-10 41.8 0.0 4.4e-10 40.0 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin DUF5584 PF17822.1 OAP63237.1 - 0.026 14.0 0.0 0.034 13.6 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5584) DSBA PF01323.20 OAP63237.1 - 0.13 12.0 0.5 0.28 10.9 0.1 1.8 2 1 0 2 2 2 0 DSBA-like thioredoxin domain CKS PF01111.19 OAP63238.1 - 1.1e-32 112.1 0.3 1.1e-32 112.1 0.3 1.6 2 0 0 2 2 2 1 Cyclin-dependent kinase regulatory subunit Bromodomain PF00439.25 OAP63239.1 - 2e-37 127.1 6.5 5.9e-19 67.9 0.6 2.4 2 0 0 2 2 2 2 Bromodomain Mucin PF01456.17 OAP63239.1 - 0.0086 16.1 12.0 0.023 14.7 12.0 1.7 1 0 0 1 1 1 1 Mucin-like glycoprotein DUF3844 PF12955.7 OAP63240.1 - 3.9e-34 116.9 6.5 5.8e-34 116.4 6.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) TMEM156 PF15106.6 OAP63240.1 - 0.055 12.9 0.3 0.081 12.4 0.3 1.2 1 0 0 1 1 1 0 TMEM156 protein family NAGidase PF07555.13 OAP63241.1 - 0.073 12.4 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 beta-N-acetylglucosaminidase TPT PF03151.16 OAP63242.1 - 7.5e-11 41.9 7.0 2.1e-08 33.9 2.6 3.2 2 2 0 2 2 2 2 Triose-phosphate Transporter family RRF PF01765.19 OAP63243.1 - 1e-32 113.3 0.5 1.7e-32 112.6 0.5 1.4 1 0 0 1 1 1 1 Ribosome recycling factor Phi-29_GP3 PF05435.11 OAP63243.1 - 0.1 12.0 1.6 0.51 9.8 0.0 2.0 2 0 0 2 2 2 0 Phi-29 DNA terminal protein GP3 RtcB PF01139.17 OAP63243.1 - 0.28 10.3 3.0 0.54 9.4 3.0 1.4 1 0 0 1 1 1 0 tRNA-splicing ligase RtcB HSP70 PF00012.20 OAP63244.1 - 2.4e-208 693.2 16.8 1.8e-191 637.4 3.2 2.0 1 1 1 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 OAP63244.1 - 9.3e-16 57.5 0.3 1.7e-14 53.4 0.1 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 OAP63244.1 - 0.00017 21.3 0.0 0.00036 20.3 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 OAP63244.1 - 0.11 12.9 3.5 7.3 7.1 0.1 3.4 2 1 0 2 2 2 0 Cell division protein FtsA ATP-synt_DE PF00401.20 OAP63244.1 - 0.11 12.8 5.8 0.35 11.2 1.4 2.8 2 0 0 2 2 2 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain RTA1 PF04479.13 OAP63245.1 - 1.3e-59 201.3 7.6 1.3e-59 201.3 7.6 1.9 1 1 1 2 2 2 1 RTA1 like protein DUF2207 PF09972.9 OAP63245.1 - 7.7 5.2 6.3 2.2 7.0 0.1 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Fungal_trans_2 PF11951.8 OAP63246.1 - 0.0018 17.2 0.0 0.0031 16.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain GTP_EFTU PF00009.27 OAP63247.1 - 1.3e-47 161.8 0.0 1.9e-47 161.3 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFTUD2 PF16004.5 OAP63247.1 - 1.6e-37 128.8 10.7 2.9e-37 127.9 10.7 1.4 1 0 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_IV PF03764.18 OAP63247.1 - 6.6e-23 80.8 0.0 1.9e-22 79.3 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 OAP63247.1 - 2.6e-16 59.4 0.0 7.2e-16 58.0 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 OAP63247.1 - 6.3e-08 32.9 0.0 1.8e-07 31.4 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 OAP63247.1 - 9.9e-07 28.8 0.1 3.6e-06 27.0 0.0 2.0 2 0 0 2 2 2 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 OAP63247.1 - 0.00058 19.9 0.1 0.0011 19.0 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 OAP63247.1 - 0.018 14.6 0.0 0.038 13.6 0.0 1.5 1 0 0 1 1 1 0 Ras family Septin PF00735.18 OAP63247.1 - 0.098 11.9 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Septin Thiolase_N PF00108.23 OAP63248.1 - 1.5e-92 309.6 0.2 6.4e-92 307.6 0.0 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 OAP63248.1 - 1.3e-44 150.8 3.2 1.6e-44 150.5 2.0 1.9 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 OAP63248.1 - 9.5e-06 25.4 1.6 2.8e-05 23.8 0.8 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 OAP63248.1 - 0.0018 18.1 2.2 0.066 13.1 0.1 2.8 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III IBR PF01485.21 OAP63249.1 - 2.4e-08 34.1 8.0 2.4e-08 34.1 8.0 3.6 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain JmjN PF02375.17 OAP63249.1 - 0.11 12.5 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 jmjN domain zf-RING_UBOX PF13445.6 OAP63249.1 - 2.8 8.0 13.6 0.3 11.1 5.5 2.8 2 1 0 2 2 2 0 RING-type zinc-finger HSP20 PF00011.21 OAP63250.1 - 4.8e-09 36.3 0.0 2.8e-08 33.8 0.0 1.9 1 1 0 1 1 1 1 Hsp20/alpha crystallin family HSP20 PF00011.21 OAP63251.1 - 2.9e-08 33.8 0.0 5.3e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Hsp20/alpha crystallin family RhoGAP PF00620.27 OAP63252.1 - 1.4e-37 128.9 0.1 3e-37 127.8 0.1 1.5 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.22 OAP63252.1 - 2.3e-32 111.0 32.8 2.4e-12 46.9 4.9 5.0 5 0 0 5 5 5 4 LIM domain LPD30 PF18850.1 OAP63252.1 - 0.095 12.5 0.3 0.28 10.9 0.3 1.7 1 0 0 1 1 1 0 Large polyvalent protein associated domain 30 Desulfoferrod_N PF06397.12 OAP63252.1 - 0.25 11.0 1.1 0.65 9.7 0.1 2.3 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain zf-ACC PF17848.1 OAP63252.1 - 1 9.5 4.2 14 5.9 0.1 3.7 3 0 0 3 3 3 0 Acetyl-coA carboxylase zinc finger domain Beta_elim_lyase PF01212.21 OAP63253.1 - 1.4e-70 237.9 0.1 1.7e-70 237.6 0.1 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 OAP63253.1 - 1.7e-05 24.1 0.0 2.3e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 OAP63253.1 - 0.0024 16.5 0.0 0.0056 15.3 0.0 1.4 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 OAP63253.1 - 0.054 12.8 0.1 0.13 11.5 0.0 1.6 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Yippee-Mis18 PF03226.14 OAP63254.1 - 4.5e-05 23.6 1.2 0.00013 22.1 1.3 1.7 1 1 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly CENP-H PF05837.12 OAP63254.1 - 0.87 10.0 7.1 0.59 10.6 0.3 3.3 3 1 0 3 3 3 0 Centromere protein H (CENP-H) Pkinase PF00069.25 OAP63255.1 - 6.4e-65 219.1 0.0 3e-64 216.9 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP63255.1 - 8.5e-33 113.7 0.0 1.9e-32 112.6 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 OAP63255.1 - 2.5e-09 37.4 0.1 6.7e-09 36.0 0.1 1.8 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 OAP63255.1 - 0.00017 21.9 0.0 0.00049 20.4 0.0 1.7 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Kinase-like PF14531.6 OAP63255.1 - 0.025 13.9 0.0 0.46 9.8 0.0 2.1 1 1 0 1 1 1 0 Kinase-like Kdo PF06293.14 OAP63255.1 - 0.053 12.9 0.0 0.093 12.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 OAP63255.1 - 0.089 11.7 0.1 0.13 11.2 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.23 OAP63255.1 - 0.092 12.7 0.0 0.42 10.5 0.1 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Glyco_transf_34 PF05637.12 OAP63256.1 - 4.2e-45 154.3 0.0 1.2e-41 143.0 0.0 2.2 1 1 1 2 2 2 2 galactosyl transferase GMA12/MNN10 family Fungus-induced PF10917.8 OAP63256.1 - 6e-05 23.3 0.1 0.00011 22.4 0.1 1.4 1 0 0 1 1 1 1 Fungus-induced protein HEPN_RES_NTD1 PF18870.1 OAP63256.1 - 0.065 13.4 0.4 0.18 12.0 0.4 1.7 1 0 0 1 1 1 0 HEPN/RES N-terminal domain 1 Peptidase_S9 PF00326.21 OAP63257.1 - 0.00014 21.4 0.0 0.00016 21.2 0.0 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_4 PF08386.10 OAP63257.1 - 0.11 12.6 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 TAP-like protein Cytomega_UL84 PF06284.11 OAP63258.1 - 1.6 7.1 9.8 2.1 6.7 9.8 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein FAM176 PF14851.6 OAP63258.1 - 2.2 7.9 6.5 3.1 7.5 6.5 1.2 1 0 0 1 1 1 0 FAM176 family Phage_Gp23 PF10669.9 OAP63258.1 - 2.7 8.3 11.7 3.7 7.9 11.7 1.2 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) Connexin PF00029.19 OAP63258.1 - 3.1 7.5 4.0 3.9 7.2 4.0 1.1 1 0 0 1 1 1 0 Connexin DUF3464 PF11947.8 OAP63258.1 - 3.6 7.3 6.3 5.4 6.8 6.3 1.2 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Peptidase_S49_N PF08496.10 OAP63258.1 - 4.9 7.2 7.1 7.5 6.6 7.1 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal p450 PF00067.22 OAP63259.1 - 2.9e-50 171.4 0.0 3.8e-50 171.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 WSC PF01822.19 OAP63261.1 - 7.6e-97 317.7 111.7 7.8e-19 67.7 7.2 6.8 6 0 0 6 6 6 6 WSC domain PQQ_3 PF13570.6 OAP63261.1 - 0.075 13.6 9.0 3.8 8.1 0.1 4.7 3 0 0 3 3 3 0 PQQ-like domain ASH PF15780.5 OAP63261.1 - 0.27 11.5 19.6 0.3 11.3 0.0 4.6 5 0 0 5 5 5 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin GFA PF04828.14 OAP63263.1 - 6.8e-13 48.8 0.1 1.2e-12 48.0 0.1 1.4 1 1 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Sugar_tr PF00083.24 OAP63264.1 - 2.1e-78 264.2 22.9 2.6e-78 263.9 22.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP63264.1 - 3e-21 75.7 28.6 3e-21 75.7 28.6 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Fungal_trans PF04082.18 OAP63265.1 - 7.5e-28 97.3 0.0 1.5e-27 96.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans_2 PF11951.8 OAP63265.1 - 0.0072 15.2 3.6 0.029 13.2 0.0 2.6 3 0 0 3 3 3 2 Fungal specific transcription factor domain MFS_1 PF07690.16 OAP63266.1 - 1.7e-52 178.5 32.4 1.7e-52 178.5 32.4 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAP63266.1 - 3.9e-12 45.8 18.5 3.9e-12 45.8 18.5 2.5 1 1 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 OAP63266.1 - 1.3e-07 31.3 2.0 1.3e-07 31.3 2.0 2.5 3 0 0 3 3 3 2 Uncharacterised MFS-type transporter YbfB TRI12 PF06609.13 OAP63266.1 - 1.2e-06 27.2 3.4 1.2e-06 27.2 3.4 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) LPD38 PF18857.1 OAP63266.1 - 0.039 14.1 0.0 0.089 12.9 0.0 1.5 1 0 0 1 1 1 0 Large polyvalent protein associated domain 38 DUF1673 PF07895.11 OAP63266.1 - 3.6 7.3 5.8 5.9 6.5 0.2 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1673) OATP PF03137.20 OAP63266.1 - 4.1 5.6 16.4 0.022 13.1 2.8 3.4 1 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Septin PF00735.18 OAP63268.1 - 2.9e-12 46.4 0.0 6.3e-08 32.2 0.0 2.1 2 0 0 2 2 2 2 Septin AAA_16 PF13191.6 OAP63268.1 - 7.8e-05 23.1 0.0 0.00021 21.7 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 OAP63268.1 - 0.0038 17.3 0.0 0.0092 16.1 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase ATPase_2 PF01637.18 OAP63268.1 - 0.017 15.1 0.0 0.093 12.6 0.0 1.8 1 1 0 2 2 2 0 ATPase domain predominantly from Archaea NTPase_1 PF03266.15 OAP63268.1 - 0.02 14.8 0.0 0.036 14.0 0.0 1.4 1 0 0 1 1 1 0 NTPase AAA PF00004.29 OAP63268.1 - 0.034 14.6 0.0 0.069 13.6 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 OAP63268.1 - 0.055 13.4 0.2 0.2 11.5 0.1 2.0 2 0 0 2 2 2 0 RsgA GTPase Roc PF08477.13 OAP63268.1 - 0.12 12.6 0.0 0.25 11.6 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 OAP63268.1 - 0.19 11.2 0.1 0.68 9.4 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region NTF2 PF02136.20 OAP63269.1 - 2.2e-25 89.5 0.1 3.4e-25 88.9 0.1 1.3 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.22 OAP63269.1 - 2.3e-07 30.5 0.0 4.1e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OAP63269.1 - 0.033 14.0 0.0 0.062 13.2 0.0 1.4 1 0 0 1 1 1 0 Occluded RNA-recognition motif DUF5321 PF17254.2 OAP63270.1 - 1.6e-31 108.9 11.5 1.9e-31 108.7 11.5 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5321) Peptidase_C50 PF03568.17 OAP63271.1 - 6e-126 420.7 0.0 1.3e-125 419.6 0.0 1.6 1 0 0 1 1 1 1 Peptidase family C50 TPR_12 PF13424.6 OAP63271.1 - 1.7e-06 28.2 15.4 4.6e-06 26.8 0.2 5.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 OAP63271.1 - 0.0016 18.2 0.5 0.13 12.1 0.3 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat CHAT PF12770.7 OAP63271.1 - 0.0028 17.1 0.0 1.1 8.6 0.0 2.5 2 0 0 2 2 2 2 CHAT domain TPR_2 PF07719.17 OAP63271.1 - 0.05 13.7 11.1 0.92 9.8 0.1 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 OAP63271.1 - 0.14 12.3 1.4 35 4.8 0.1 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 OAP63271.1 - 0.16 12.5 10.7 0.3 11.6 0.1 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_MalT PF17874.1 OAP63271.1 - 0.23 10.8 13.2 0.44 9.9 0.8 3.8 3 1 0 3 3 3 0 MalT-like TPR region TPR_8 PF13181.6 OAP63271.1 - 2.1 8.8 3.9 24 5.5 0.2 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF898 PF05987.13 OAP63272.1 - 0.0097 15.0 1.0 0.012 14.7 1.0 1.2 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF898) Methyltransf_23 PF13489.6 OAP63273.1 - 5.6e-17 62.1 0.0 7.1e-17 61.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAP63273.1 - 1.9e-14 54.2 0.0 3.3e-14 53.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAP63273.1 - 7.6e-14 52.2 0.0 1.7e-13 51.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAP63273.1 - 1.1e-13 51.6 0.0 2.6e-13 50.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAP63273.1 - 8.9e-12 45.1 0.0 2.2e-11 43.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 OAP63273.1 - 0.00017 21.2 0.0 0.0011 18.7 0.0 1.9 2 0 0 2 2 2 1 Nodulation protein S (NodS) RrnaAD PF00398.20 OAP63273.1 - 0.00032 19.9 0.0 0.00041 19.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Ubie_methyltran PF01209.18 OAP63273.1 - 0.00033 20.1 0.0 0.0012 18.2 0.0 1.9 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.9 OAP63273.1 - 0.015 15.0 0.0 0.02 14.6 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase MTS PF05175.14 OAP63273.1 - 0.02 14.4 0.0 0.033 13.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_32 PF13679.6 OAP63273.1 - 0.088 12.8 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain tRNA_U5-meth_tr PF05958.11 OAP63273.1 - 0.18 10.7 0.0 0.24 10.3 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Methyltransf_9 PF08003.11 OAP63273.1 - 0.24 10.3 0.0 1.3 7.9 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1698) TPP_enzyme_M PF00205.22 OAP63274.1 - 5.7e-36 123.3 0.0 2.2e-35 121.3 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_N PF02776.18 OAP63274.1 - 5.1e-32 110.8 0.2 1.7e-31 109.1 0.1 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 OAP63274.1 - 6.6e-19 68.2 0.4 7.3e-18 64.8 0.4 2.3 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain B12-binding PF02310.19 OAP63274.1 - 0.0031 17.5 0.1 0.01 15.9 0.1 1.8 1 0 0 1 1 1 1 B12 binding domain DUF5389 PF17364.2 OAP63275.1 - 0.11 12.6 0.8 0.19 11.8 0.8 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5389) Chal_sti_synt_N PF00195.19 OAP63276.1 - 1.9e-23 83.1 0.0 2.9e-23 82.5 0.0 1.2 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain Chal_sti_synt_C PF02797.15 OAP63276.1 - 1.9e-17 63.7 0.0 5.1e-17 62.3 0.0 1.6 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain ACP_syn_III_C PF08541.10 OAP63276.1 - 7.4e-05 22.8 0.0 0.00016 21.7 0.0 1.6 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.10 OAP63276.1 - 0.007 16.2 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III FAE1_CUT1_RppA PF08392.12 OAP63276.1 - 0.024 14.0 0.0 0.034 13.4 0.0 1.2 1 0 0 1 1 1 0 FAE1/Type III polyketide synthase-like protein p450 PF00067.22 OAP63277.1 - 3.5e-51 174.4 0.0 2.7e-50 171.5 0.0 2.1 1 1 0 1 1 1 1 Cytochrome P450 Ank_2 PF12796.7 OAP63278.1 - 6.1e-41 138.9 0.1 1.1e-13 51.6 0.0 3.4 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) DHHC PF01529.20 OAP63278.1 - 1.9e-35 121.9 10.4 1.9e-35 121.9 10.4 2.6 2 1 0 2 2 2 1 DHHC palmitoyltransferase Ank PF00023.30 OAP63278.1 - 1.6e-23 82.0 1.2 1.5e-06 28.4 0.0 5.4 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 OAP63278.1 - 1.7e-22 77.0 3.4 4.3e-07 29.7 0.0 6.5 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.6 OAP63278.1 - 3.1e-21 75.4 1.6 2e-06 28.2 0.0 4.3 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 OAP63278.1 - 3.3e-21 75.1 1.5 1.4e-07 31.6 0.0 4.7 2 1 4 6 6 6 5 Ankyrin repeats (many copies) PocR PF10114.9 OAP63278.1 - 0.64 9.8 2.3 1.2 8.9 2.3 1.3 1 0 0 1 1 1 0 Sensory domain found in PocR ATP-synt_ab PF00006.25 OAP63279.1 - 6e-73 245.0 0.0 8.9e-73 244.5 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 OAP63279.1 - 9.4e-48 161.7 1.9 1.6e-47 160.9 1.9 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 OAP63279.1 - 1.2e-14 54.6 2.3 1.2e-14 54.6 2.3 2.1 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain ADH_N PF08240.12 OAP63280.1 - 6e-07 29.3 0.1 1.8e-06 27.8 0.1 1.8 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAP63280.1 - 0.026 14.5 0.1 0.089 12.8 0.1 2.0 1 1 0 1 1 1 0 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 OAP63280.1 - 0.097 12.6 0.0 0.26 11.2 0.0 1.7 1 1 0 1 1 1 0 N-terminal domain of oxidoreductase CorA PF01544.18 OAP63281.1 - 0.0058 16.0 9.2 0.0058 16.0 9.2 1.9 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein Plasmo_rep PF12135.8 OAP63281.1 - 0.2 11.3 0.6 0.49 10.0 0.6 1.6 1 0 0 1 1 1 0 Plasmodium repeat family FAM76 PF16046.5 OAP63281.1 - 7.5 5.8 20.4 21 4.3 20.4 1.8 1 0 0 1 1 1 0 FAM76 protein tRNA-synt_His PF13393.6 OAP63282.1 - 5.5e-41 140.8 0.0 9.9e-35 120.3 0.0 2.1 2 0 0 2 2 2 2 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 OAP63282.1 - 1.4e-10 41.2 0.0 3e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain RNase_P_p30 PF01876.16 OAP63284.1 - 9.8e-61 204.9 0.0 1.3e-60 204.5 0.0 1.2 1 0 0 1 1 1 1 RNase P subunit p30 DUF746 PF05344.11 OAP63284.1 - 0.068 13.0 0.0 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 Domain of Unknown Function (DUF746) Pkinase PF00069.25 OAP63285.1 - 3.9e-64 216.6 0.0 4.5e-64 216.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP63285.1 - 6.7e-18 64.9 0.0 1.2e-17 64.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OAP63285.1 - 8.1e-07 29.2 0.3 0.00012 22.1 0.1 2.5 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OAP63285.1 - 0.0044 15.9 0.0 0.0076 15.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 OAP63285.1 - 0.0055 16.1 0.0 0.0084 15.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OAP63285.1 - 0.027 13.8 0.2 0.052 12.9 0.2 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 OAP63285.1 - 0.072 12.7 0.7 0.13 11.8 0.1 1.8 2 0 0 2 2 2 0 Choline/ethanolamine kinase Methyltransf_2 PF00891.18 OAP63286.1 - 1.3e-21 76.8 0.0 2e-21 76.3 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 OAP63286.1 - 0.00025 20.9 0.1 0.00071 19.5 0.1 1.7 1 0 0 1 1 1 1 Dimerisation domain Dimerisation PF08100.11 OAP63286.1 - 0.00084 19.3 0.2 0.0022 18.0 0.2 1.8 1 0 0 1 1 1 1 Dimerisation domain tRNA-synt_1 PF00133.22 OAP63288.1 - 1.7e-212 707.0 1.2 1.9e-211 703.5 1.2 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 OAP63288.1 - 7.5e-33 113.6 5.5 1.7e-32 112.5 0.1 2.4 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 OAP63288.1 - 1.3e-12 47.2 0.8 0.00011 21.1 0.1 4.3 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 OAP63288.1 - 7.9e-07 28.8 9.0 1.2e-06 28.2 0.1 3.9 3 1 1 4 4 4 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 OAP63288.1 - 0.0018 17.6 0.0 0.03 13.7 0.0 2.5 2 1 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain Tox-SHH PF15652.6 OAP63288.1 - 0.25 12.3 2.6 1.4 9.9 2.1 2.5 2 0 0 2 2 2 0 HNH/Endo VII superfamily toxin with a SHH signature Cation_efflux PF01545.21 OAP63289.1 - 3.2e-52 177.2 6.4 4.1e-52 176.8 6.4 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 OAP63289.1 - 0.00017 21.7 0.0 0.00044 20.3 0.0 1.7 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter SelP_N PF04592.14 OAP63289.1 - 0.44 9.9 17.2 0.024 14.0 2.4 2.4 2 0 0 2 2 2 0 Selenoprotein P, N terminal region FGGY_C PF02782.16 OAP63290.1 - 2.6e-30 105.6 0.0 4.1e-30 105.0 0.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 OAP63290.1 - 1.3e-18 67.5 0.0 6.3e-13 48.8 0.0 2.2 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain DUF846 PF05832.12 OAP63291.1 - 3.7e-47 159.9 9.9 4.4e-47 159.6 9.9 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) TMEM220 PF15071.6 OAP63291.1 - 0.026 15.2 0.6 0.026 15.2 0.6 1.7 2 0 0 2 2 2 0 Transmembrane family 220, helix MpPF26 PF07666.11 OAP63291.1 - 0.065 13.3 7.0 0.27 11.3 0.1 2.1 2 0 0 2 2 2 0 M penetrans paralogue family 26 DUF443 PF04276.12 OAP63291.1 - 0.092 12.5 0.5 0.092 12.5 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF443) PAP2_3 PF14378.6 OAP63291.1 - 0.094 12.4 7.5 0.12 12.0 7.5 1.1 1 0 0 1 1 1 0 PAP2 superfamily TctB PF07331.11 OAP63291.1 - 2.9 8.2 13.3 8.3 6.7 1.3 2.3 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family Exo_endo_phos PF03372.23 OAP63293.1 - 4.7e-13 49.2 2.7 1.9e-12 47.2 0.3 2.6 2 1 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family LRR_8 PF13855.6 OAP63293.1 - 3.2e-09 36.4 4.1 7.8e-09 35.2 4.1 1.7 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 OAP63293.1 - 3.9e-09 36.7 5.6 1.1e-06 28.8 0.3 2.7 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OAP63293.1 - 0.012 16.0 3.5 2.8 8.8 0.7 4.3 4 1 0 4 4 4 0 Leucine Rich Repeat LRR_9 PF14580.6 OAP63293.1 - 0.019 14.5 0.2 0.035 13.6 0.2 1.3 1 0 0 1 1 1 0 Leucine-rich repeat LRR_6 PF13516.6 OAP63293.1 - 0.64 10.2 6.1 2.1 8.6 0.2 3.2 3 0 0 3 3 3 0 Leucine Rich repeat Complex1_LYR PF05347.15 OAP63294.1 - 9.1e-08 32.0 0.1 1.3e-07 31.6 0.1 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 OAP63294.1 - 3e-06 27.9 1.1 3.7e-06 27.6 1.1 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Peptidase_S15 PF02129.18 OAP63295.1 - 1.2e-36 126.7 0.0 7.6e-34 117.5 0.0 2.2 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 OAP63295.1 - 9.6e-30 104.2 0.0 1.3e-29 103.8 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain MFS_1 PF07690.16 OAP63296.1 - 4.4e-37 127.8 28.5 4.4e-37 127.8 28.5 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.16 OAP63297.1 - 3.5e-18 65.7 38.1 1.8e-16 60.0 23.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Wzy_C PF04932.15 OAP63297.1 - 1.2 8.8 0.0 1.2 8.8 0.0 3.6 4 1 0 4 4 4 0 O-Antigen ligase ECH_1 PF00378.20 OAP63298.1 - 5.3e-40 137.3 0.0 7.1e-40 136.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAP63298.1 - 8.7e-25 87.9 0.2 1.1e-22 81.0 0.1 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Abhydrolase_3 PF07859.13 OAP63299.1 - 3.3e-37 128.4 0.1 1.3e-36 126.4 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Fungal_trans_2 PF11951.8 OAP63300.1 - 1.6e-09 37.0 0.5 1.6e-09 37.0 0.5 2.0 3 0 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP63300.1 - 4.1e-08 33.2 5.0 6.5e-08 32.6 5.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RTA1 PF04479.13 OAP63301.1 - 1.7e-51 174.8 10.6 2.7e-51 174.1 10.6 1.3 1 0 0 1 1 1 1 RTA1 like protein DUF4357 PF14267.6 OAP63301.1 - 0.2 11.6 0.5 0.38 10.7 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4357) PSII PF00421.19 OAP63301.1 - 0.82 8.3 8.2 0.4 9.3 0.1 2.1 1 1 1 2 2 2 0 Photosystem II protein Cyclin_N PF00134.23 OAP63303.1 - 7.5e-16 58.0 0.4 1.3e-15 57.3 0.4 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 OAP63303.1 - 3.8e-05 23.8 0.0 0.0032 17.6 0.0 2.7 2 1 0 2 2 2 1 Cyclin, C-terminal domain TFIIB PF00382.19 OAP63303.1 - 0.027 14.5 0.2 0.088 12.9 0.1 1.9 2 0 0 2 2 2 0 Transcription factor TFIIB repeat Cyclin_C_2 PF16899.5 OAP63303.1 - 0.045 14.2 0.1 0.18 12.2 0.0 2.0 2 0 0 2 2 2 0 Cyclin C-terminal domain Fungal_trans_2 PF11951.8 OAP63304.1 - 0.0014 17.6 0.9 0.48 9.2 0.1 2.4 2 0 0 2 2 2 2 Fungal specific transcription factor domain MFS_1 PF07690.16 OAP63305.1 - 3.4e-31 108.4 32.4 3.4e-31 108.4 32.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OPT PF03169.15 OAP63306.1 - 5.5e-155 517.5 24.6 6.2e-155 517.3 24.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein UL42 PF17638.2 OAP63306.1 - 7.9 6.5 8.3 1.5 8.8 0.2 3.5 3 1 1 4 4 4 0 HCMV UL42 HATPase_c PF02518.26 OAP63307.1 - 2.5e-21 76.3 0.1 9.2e-21 74.4 0.1 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 OAP63307.1 - 2.9e-19 69.3 0.0 6.3e-19 68.2 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 OAP63307.1 - 1.8e-11 43.9 0.0 8.4e-11 41.8 0.0 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain ZapB PF06005.12 OAP63308.1 - 6.8 7.2 8.7 3 8.3 5.0 2.2 2 1 0 2 2 2 0 Cell division protein ZapB MFS_1 PF07690.16 OAP63309.1 - 1.2e-36 126.4 56.6 1.4e-36 126.2 53.4 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily adh_short_C2 PF13561.6 OAP63310.1 - 3.2e-49 167.6 0.8 8.3e-41 140.1 0.5 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP63310.1 - 5.3e-47 159.8 0.5 6.9e-47 159.4 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAP63310.1 - 3.7e-13 49.8 0.0 5.2e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 OAP63310.1 - 0.0035 17.2 0.1 0.0055 16.6 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 OAP63310.1 - 0.01 15.9 0.5 0.02 15.0 0.5 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain DDE_Tnp_1 PF01609.21 OAP63310.1 - 0.019 14.6 0.0 0.026 14.2 0.0 1.2 1 0 0 1 1 1 0 Transposase DDE domain YrhK PF14145.6 OAP63311.1 - 0.41 10.6 21.7 0.18 11.7 0.5 4.8 4 1 0 4 4 4 0 YrhK-like protein Clr5 PF14420.6 OAP63312.1 - 6.5e-06 26.3 0.5 1.6e-05 25.0 0.3 1.8 2 0 0 2 2 2 1 Clr5 domain adh_short_C2 PF13561.6 OAP63313.1 - 4.1e-53 180.3 2.8 4.8e-53 180.1 2.8 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP63313.1 - 3.8e-47 160.3 3.6 5e-47 159.9 3.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAP63313.1 - 2.7e-12 47.0 1.4 3.8e-12 46.5 1.4 1.1 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 OAP63313.1 - 0.014 15.3 0.2 0.023 14.6 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 OAP63313.1 - 0.014 15.4 1.2 0.024 14.7 1.2 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IMPDH PF00478.25 OAP63313.1 - 0.02 13.9 4.3 0.016 14.2 2.8 1.7 1 1 1 2 2 2 0 IMP dehydrogenase / GMP reductase domain Epimerase PF01370.21 OAP63313.1 - 0.2 11.1 0.9 1.4 8.3 0.9 2.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Cas_Cas02710 PF09670.10 OAP63313.1 - 0.24 10.1 0.0 0.33 9.7 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cas02710) Fungal_trans_2 PF11951.8 OAP63314.1 - 9.4e-07 28.0 0.0 1.5e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain HrpB1_HrpK PF09613.10 OAP63315.1 - 0.0082 15.8 0.4 2.9 7.6 0.0 3.1 3 0 0 3 3 3 2 Bacterial type III secretion protein (HrpB1_HrpK) Haem_degrading PF03928.14 OAP63316.1 - 2.2e-25 89.0 0.1 2.6e-25 88.8 0.1 1.1 1 0 0 1 1 1 1 Haem-degrading SLAC1 PF03595.17 OAP63317.1 - 7.1e-85 285.1 36.7 8e-85 284.9 36.7 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Hva1_TUDOR PF11160.8 OAP63318.1 - 3.2e-16 59.2 5.1 3.2e-16 59.2 5.1 3.1 3 1 0 3 3 3 1 Hypervirulence associated proteins TUDOR domain CHZ PF09649.10 OAP63319.1 - 0.0021 17.5 1.9 0.0057 16.1 1.9 1.8 1 0 0 1 1 1 1 Histone chaperone domain CHZ CPDase PF07823.11 OAP63320.1 - 3.4e-32 111.8 0.0 3.8e-32 111.6 0.0 1.0 1 0 0 1 1 1 1 Cyclic phosphodiesterase-like protein 2_5_RNA_ligase2 PF13563.6 OAP63320.1 - 0.00056 19.8 0.0 0.56 10.1 0.0 2.1 1 1 1 2 2 2 2 2'-5' RNA ligase superfamily p450 PF00067.22 OAP63321.1 - 9.6e-67 225.7 0.0 1.1e-66 225.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 NAD_binding_8 PF13450.6 OAP63322.1 - 1.3e-07 31.7 0.2 9.5e-07 29.0 0.2 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAP63322.1 - 8.1e-07 28.6 0.0 1.5e-05 24.4 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAP63322.1 - 7.8e-05 22.7 0.0 0.0044 17.0 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 OAP63322.1 - 0.00064 19.1 1.2 0.0015 17.9 1.2 1.6 1 0 0 1 1 1 1 FAD binding domain K_oxygenase PF13434.6 OAP63322.1 - 0.00074 18.8 0.0 0.0021 17.3 0.0 1.7 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Shikimate_DH PF01488.20 OAP63322.1 - 0.0013 18.8 0.0 0.78 9.8 0.0 2.4 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase FMO-like PF00743.19 OAP63322.1 - 0.0014 17.1 0.0 0.039 12.4 0.0 2.1 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like FAD_binding_2 PF00890.24 OAP63322.1 - 0.019 14.1 1.4 0.04 13.0 1.4 1.6 1 0 0 1 1 1 0 FAD binding domain ThiF PF00899.21 OAP63322.1 - 0.041 13.2 0.5 0.53 9.6 0.3 2.2 2 0 0 2 2 2 0 ThiF family 2-Hacid_dh_C PF02826.19 OAP63322.1 - 0.073 12.4 0.0 0.35 10.2 0.0 2.0 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox PF00070.27 OAP63322.1 - 0.074 13.6 1.6 14 6.4 0.0 2.8 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAP63322.1 - 0.077 12.2 0.1 7 5.8 0.0 2.8 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAP63322.1 - 0.25 10.9 4.2 0.89 9.1 1.8 2.7 3 1 0 3 3 3 0 FAD dependent oxidoreductase DUF3425 PF11905.8 OAP63323.1 - 2e-12 47.1 0.0 5.5e-12 45.8 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 OAP63323.1 - 1.6e-06 28.1 5.6 3e-06 27.2 5.6 1.4 1 0 0 1 1 1 1 bZIP transcription factor TolA_bind_tri PF16331.5 OAP63323.1 - 0.012 15.7 0.8 0.024 14.7 0.8 1.4 1 0 0 1 1 1 0 TolA binding protein trimerisation bZIP_2 PF07716.15 OAP63323.1 - 0.02 15.0 6.2 0.02 15.0 6.2 2.1 1 1 1 2 2 2 0 Basic region leucine zipper Med9 PF07544.13 OAP63323.1 - 0.042 13.9 1.8 0.15 12.1 0.8 2.1 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 HMW1C_N PF18071.1 OAP63323.1 - 0.23 11.3 1.6 0.29 10.9 0.6 1.6 2 0 0 2 2 2 0 HMW1C N-terminal bZIP_Maf PF03131.17 OAP63323.1 - 0.33 11.5 7.3 0.66 10.5 7.3 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor Ribosomal_L5_C PF00673.21 OAP63324.1 - 0.035 14.3 0.0 0.036 14.2 0.0 1.1 1 0 0 1 1 1 0 ribosomal L5P family C-terminus ERCC4 PF02732.15 OAP63325.1 - 5.1e-27 95.0 0.0 8.5e-27 94.3 0.0 1.4 1 0 0 1 1 1 1 ERCC4 domain HHH_8 PF14716.6 OAP63325.1 - 0.063 13.7 0.0 0.14 12.5 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix domain MARVEL PF01284.23 OAP63326.1 - 0.0033 17.4 5.4 0.0055 16.7 5.4 1.4 1 1 0 1 1 1 1 Membrane-associating domain Pyr_redox_2 PF07992.14 OAP63328.1 - 2.7e-40 138.5 0.0 3.2e-40 138.2 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAP63328.1 - 1.3e-08 35.3 0.0 1.3e-06 28.8 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAP63328.1 - 0.014 15.6 0.0 4.8 7.5 0.0 3.3 2 1 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 OAP63328.1 - 0.026 13.8 0.0 7 5.8 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 OAP63328.1 - 0.063 12.5 0.5 1.7 7.8 0.1 2.8 3 0 0 3 3 3 0 FAD binding domain NAD_binding_9 PF13454.6 OAP63328.1 - 0.077 13.0 0.1 4.5 7.2 0.0 2.9 2 1 1 3 3 3 0 FAD-NAD(P)-binding CUE PF02845.16 OAP63329.1 - 2.7e-05 23.8 0.0 4.7e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 CUE domain DUF1296 PF06972.11 OAP63329.1 - 0.011 15.9 0.0 0.02 15.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1296) GST_N PF02798.20 OAP63331.1 - 1.3e-16 60.7 0.0 3e-16 59.5 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OAP63331.1 - 1.1e-13 51.1 0.0 1.9e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 OAP63331.1 - 1.6e-12 47.7 0.0 3e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 OAP63331.1 - 5.5e-09 36.1 0.0 1e-08 35.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 OAP63331.1 - 1.1e-08 35.3 0.0 2e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAP63331.1 - 0.0014 18.6 0.0 0.0024 17.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Oxysterol_BP PF01237.18 OAP63332.1 - 6.6e-61 206.2 6.6 7.2e-53 179.8 0.0 2.0 1 1 1 2 2 2 2 Oxysterol-binding protein Phage-tail_3 PF13550.6 OAP63332.1 - 0.022 14.6 0.1 0.065 13.1 0.1 1.7 2 0 0 2 2 2 0 Putative phage tail protein F_bP_aldolase PF01116.20 OAP63333.1 - 2e-92 309.6 0.1 2.3e-92 309.5 0.1 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Arginosuc_synth PF00764.19 OAP63334.1 - 1.5e-147 491.9 0.0 1.7e-147 491.7 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 OAP63334.1 - 0.028 13.9 0.1 0.07 12.6 0.0 1.7 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC UCH PF00443.29 OAP63335.1 - 3.7e-35 121.7 0.0 2e-30 106.2 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OAP63335.1 - 2.6e-10 40.4 0.1 7.2e-10 38.9 0.1 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase HET PF06985.11 OAP63336.1 - 1.8e-23 83.5 0.3 3.5e-23 82.6 0.3 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) GrpB PF04229.14 OAP63337.1 - 4.8e-27 95.1 0.0 4e-24 85.6 0.0 2.0 1 1 1 2 2 2 2 GrpB protein RSN1_7TM PF02714.15 OAP63338.1 - 5.6e-74 248.9 26.5 1.2e-73 247.8 26.5 1.6 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 OAP63338.1 - 9.8e-41 139.9 0.0 1.5e-40 139.3 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 OAP63338.1 - 2.6e-38 131.2 0.4 9.7e-38 129.4 0.4 2.1 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport SID-1_RNA_chan PF13965.6 OAP63338.1 - 0.0065 15.0 1.3 0.0065 15.0 1.3 1.9 2 1 0 2 2 2 1 dsRNA-gated channel SID-1 TMF_TATA_bd PF12325.8 OAP63338.1 - 0.23 11.7 0.1 1.8 8.8 0.0 2.2 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding PRIMA1 PF16101.5 OAP63339.1 - 5.4 7.1 5.8 15 5.6 5.8 1.7 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Fungal_trans PF04082.18 OAP63340.1 - 3e-15 56.0 1.2 4.9e-15 55.3 1.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Peptidase_M19 PF01244.21 OAP63341.1 - 2.6e-101 339.0 0.0 3e-101 338.8 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Beta-lactamase PF00144.24 OAP63342.1 - 3.8e-30 105.3 0.0 6.1e-30 104.6 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase MFS_1 PF07690.16 OAP63343.1 - 3.5e-27 95.3 35.3 5.1e-27 94.7 35.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 OAP63343.1 - 0.00025 20.5 7.8 0.00025 20.5 7.8 2.0 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Helo_like_N PF17111.5 OAP63344.1 - 4.5e-06 26.2 0.7 6.6e-06 25.6 0.7 1.2 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins Ank_2 PF12796.7 OAP63344.1 - 0.0068 17.0 0.0 0.061 13.9 0.0 2.7 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) SesA PF17107.5 OAP63344.1 - 0.011 15.9 0.9 0.018 15.2 0.9 1.3 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Ank_4 PF13637.6 OAP63344.1 - 0.034 14.8 0.0 1.7 9.4 0.0 3.0 2 1 1 3 3 3 0 Ankyrin repeats (many copies) PRP3 PF08572.10 OAP63345.1 - 0.053 13.3 0.3 0.072 12.8 0.3 1.2 1 0 0 1 1 1 0 pre-mRNA processing factor 3 (PRP3) NUDIX PF00293.28 OAP63347.1 - 4.6e-13 49.4 0.1 1.1e-12 48.1 0.0 1.6 2 0 0 2 2 2 1 NUDIX domain Sugar_tr PF00083.24 OAP63348.1 - 4.9e-98 328.9 29.9 5.7e-98 328.7 29.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP63348.1 - 4.6e-23 81.7 42.7 8.9e-16 57.8 17.9 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily BTB PF00651.31 OAP63349.1 - 0.0064 16.7 0.0 0.018 15.3 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain Romo1 PF10247.9 OAP63350.1 - 0.012 16.0 0.2 7.8 6.9 0.0 2.3 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 Tim17 PF02466.19 OAP63350.1 - 0.047 14.1 0.6 9.3 6.7 0.1 2.2 2 0 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family Fungal_trans PF04082.18 OAP63351.1 - 8.1e-18 64.4 0.1 1.3e-17 63.7 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF4078 PF13300.6 OAP63352.1 - 6.5e-29 100.1 14.6 6.5e-29 100.1 14.6 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF4078) Dec-1 PF04624.14 OAP63352.1 - 0.041 13.7 0.6 0.19 11.6 0.6 2.1 1 0 0 1 1 1 0 Dec-1 repeat AAA PF00004.29 OAP63353.1 - 7.5e-15 55.5 0.0 1.1e-13 51.7 0.0 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BCS1_N PF08740.11 OAP63353.1 - 6.6e-13 49.0 0.1 1.1e-12 48.3 0.1 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA_16 PF13191.6 OAP63353.1 - 3.2e-06 27.7 0.6 1.5e-05 25.4 0.6 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 OAP63353.1 - 0.00038 20.5 0.0 0.00094 19.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 OAP63353.1 - 0.012 15.8 0.0 0.027 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 OAP63353.1 - 0.013 15.1 0.0 0.03 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 OAP63353.1 - 0.016 14.7 0.0 0.028 13.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_29 PF13555.6 OAP63353.1 - 0.021 14.6 0.0 0.056 13.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.6 OAP63353.1 - 0.027 14.6 0.0 0.085 13.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 OAP63353.1 - 0.029 14.6 0.0 0.076 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 OAP63353.1 - 0.035 14.5 0.0 0.082 13.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_11 PF13086.6 OAP63353.1 - 0.059 13.2 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 OAP63353.1 - 0.061 13.9 0.0 0.17 12.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 OAP63353.1 - 0.068 12.3 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 OAP63353.1 - 0.079 12.7 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein RsgA_GTPase PF03193.16 OAP63353.1 - 0.1 12.5 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase C1_2 PF03107.16 OAP63354.1 - 0.00028 21.1 5.3 0.00028 21.1 5.3 5.4 4 1 0 5 5 5 2 C1 domain zf-LITAF-like PF10601.9 OAP63355.1 - 1.8e-22 79.3 5.7 2.6e-22 78.8 5.7 1.2 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain zf-ISL3 PF14690.6 OAP63355.1 - 0.079 13.6 5.1 1.1 10.0 0.8 2.3 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-CHCC PF10276.9 OAP63355.1 - 0.36 10.9 4.3 16 5.7 0.0 3.1 3 0 0 3 3 3 0 Zinc-finger domain Asp PF00026.23 OAP63356.1 - 7.7e-54 183.2 0.0 9e-54 183.0 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OAP63356.1 - 6.2e-12 46.1 0.7 3e-06 27.6 0.0 2.3 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 OAP63356.1 - 0.0046 16.7 0.0 0.66 9.7 0.0 2.3 1 1 1 2 2 2 2 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 OAP63356.1 - 0.065 13.9 0.4 4.8 7.9 0.0 2.8 3 0 0 3 3 3 0 Aspartyl protease MtN3_slv PF03083.16 OAP63356.1 - 0.11 12.5 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 Sugar efflux transporter for intercellular exchange CFEM PF05730.11 OAP63357.1 - 1.5e-05 25.0 5.9 1.5e-05 25.0 5.9 2.6 2 0 0 2 2 2 1 CFEM domain Tme5_EGF_like PF09064.10 OAP63357.1 - 0.092 12.7 1.0 0.27 11.2 1.0 1.7 1 0 0 1 1 1 0 Thrombomodulin like fifth domain, EGF-like HATPase_c PF02518.26 OAP63358.1 - 5.8e-32 110.5 0.1 2e-31 108.8 0.0 2.0 2 0 0 2 2 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 OAP63358.1 - 5.1e-22 78.2 0.3 1.5e-21 76.6 0.1 2.0 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 OAP63358.1 - 1.2e-19 70.1 0.0 4e-19 68.4 0.0 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.6 OAP63358.1 - 2.3e-14 53.8 0.2 3.1e-13 50.2 0.0 2.7 2 0 0 2 2 2 1 GAF domain AAA_16 PF13191.6 OAP63358.1 - 7.8e-12 45.9 0.0 4.2e-11 43.5 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain GAF_3 PF13492.6 OAP63358.1 - 5.1e-08 33.3 0.0 1.3e-07 32.1 0.0 1.7 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 OAP63358.1 - 4.3e-07 30.6 0.1 1.4e-06 28.9 0.1 1.9 1 0 0 1 1 1 1 GAF domain Pkinase PF00069.25 OAP63358.1 - 1.9e-05 24.2 0.0 3.7e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain HATPase_c_3 PF13589.6 OAP63358.1 - 0.00011 22.0 0.0 0.0011 18.8 0.0 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Pkinase_Tyr PF07714.17 OAP63358.1 - 0.0016 17.8 0.0 0.0043 16.4 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase AAA_30 PF13604.6 OAP63358.1 - 0.019 14.7 0.0 0.062 13.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain TPR_12 PF13424.6 OAP63358.1 - 0.032 14.5 0.7 0.13 12.6 0.7 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat ATPase_2 PF01637.18 OAP63358.1 - 0.086 12.7 0.0 0.36 10.7 0.0 2.1 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_22 PF13401.6 OAP63358.1 - 0.11 12.7 0.1 1.5 9.1 0.0 2.9 4 0 0 4 4 3 0 AAA domain RsgA_GTPase PF03193.16 OAP63358.1 - 0.12 12.3 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase Thioredoxin_4 PF13462.6 OAP63358.1 - 1.8 8.7 4.6 0.43 10.7 0.3 2.1 2 0 0 2 2 2 0 Thioredoxin Baculo_PEP_C PF04513.12 OAP63360.1 - 0.0083 16.2 23.9 0.047 13.7 23.7 2.0 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Adeno_PV PF03910.13 OAP63360.1 - 0.045 12.4 1.7 0.052 12.3 1.7 1.1 1 0 0 1 1 1 0 Adenovirus minor core protein PV Methyltransf_34 PF11312.8 OAP63360.1 - 0.13 11.5 1.3 0.17 11.1 1.3 1.2 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase TMA7 PF09072.10 OAP63362.1 - 2.6e-25 89.0 21.1 2.9e-25 88.9 21.1 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 Arg_decarbox_C PF17944.1 OAP63363.1 - 0.00019 21.9 1.6 0.00072 20.1 1.6 2.0 1 0 0 1 1 1 1 Arginine decarboxylase C-terminal helical extension DUF812 PF05667.11 OAP63363.1 - 0.00045 19.2 1.9 0.00072 18.6 1.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Erf4 PF10256.9 OAP63363.1 - 0.011 15.8 0.0 0.066 13.3 0.0 2.3 2 1 0 2 2 2 0 Golgin subfamily A member 7/ERF4 family PilM PF07419.12 OAP63363.1 - 0.41 10.8 2.1 0.91 9.7 2.1 1.5 1 0 0 1 1 1 0 PilM DUF3669 PF12417.8 OAP63365.1 - 5.9e-06 26.4 0.0 1.1e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 Zinc finger protein Pkinase PF00069.25 OAP63366.1 - 2.9e-51 174.3 0.0 5.2e-51 173.5 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP63366.1 - 2.7e-24 85.9 0.0 2.8e-23 82.5 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 OAP63366.1 - 0.0047 15.9 0.0 0.0069 15.4 0.0 1.1 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase RIO1 PF01163.22 OAP63366.1 - 0.037 13.6 0.0 0.13 11.8 0.0 1.9 2 0 0 2 2 2 0 RIO1 family Pkinase_fungal PF17667.1 OAP63366.1 - 3.2 6.4 8.2 0.66 8.7 0.0 2.3 2 0 0 2 2 2 0 Fungal protein kinase FAD_binding_2 PF00890.24 OAP63367.1 - 2.7e-36 125.6 0.0 4e-36 125.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAP63367.1 - 0.00034 20.3 0.0 0.00083 19.0 0.0 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 OAP63367.1 - 0.0029 18.1 0.1 0.55 10.8 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAP63367.1 - 0.0058 15.9 0.1 0.047 12.9 0.1 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAP63367.1 - 0.012 14.4 0.3 2.6 6.7 0.0 2.9 3 0 0 3 3 3 0 HI0933-like protein NAD_binding_9 PF13454.6 OAP63367.1 - 0.023 14.7 0.2 0.76 9.8 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding GFA PF04828.14 OAP63368.1 - 1.2e-07 31.9 0.3 1.9e-07 31.3 0.3 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Mannosidase_ig PF17786.1 OAP63369.1 - 4.9e-17 62.3 1.7 5.4e-17 62.2 0.1 2.0 2 0 0 2 2 2 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 OAP63369.1 - 2.7e-07 31.2 0.0 1.7e-06 28.7 0.0 2.3 3 0 0 3 3 3 1 Glycosyl hydrolases family 2 Ig_mannosidase PF17753.1 OAP63369.1 - 8e-06 25.5 0.2 2.2e-05 24.1 0.2 1.7 1 0 0 1 1 1 1 Ig-fold domain Glyco_hydro_2_C PF02836.17 OAP63369.1 - 0.0051 15.9 0.2 0.033 13.3 0.0 2.2 2 1 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.18 OAP63369.1 - 0.0052 16.7 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Abhydrolase_6 PF12697.7 OAP63370.1 - 3.3e-15 57.3 0.0 4e-15 57.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAP63370.1 - 0.0003 20.1 0.0 0.0012 18.2 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DUF3425 PF11905.8 OAP63371.1 - 1.6e-12 47.5 2.7 7.2e-12 45.4 2.7 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) TPT PF03151.16 OAP63374.1 - 6.7e-14 51.9 21.8 8.3e-13 48.3 13.1 2.1 1 1 1 2 2 2 2 Triose-phosphate Transporter family UAA PF08449.11 OAP63374.1 - 0.21 10.8 17.1 0.4 9.8 17.1 1.5 1 1 0 1 1 1 0 UAA transporter family NAD_binding_8 PF13450.6 OAP63375.1 - 1e-07 32.1 0.0 2.9e-07 30.6 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 OAP63375.1 - 5.5e-07 29.2 0.0 1.4e-06 27.9 0.0 1.5 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 OAP63375.1 - 0.0019 17.5 0.1 0.012 14.9 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 OAP63375.1 - 0.004 16.4 0.1 0.0071 15.6 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 OAP63375.1 - 0.013 14.8 0.1 0.024 13.9 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 OAP63375.1 - 0.013 14.8 0.1 0.023 13.9 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 OAP63375.1 - 0.04 13.3 0.0 0.06 12.7 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase DAO PF01266.24 OAP63375.1 - 0.048 13.2 0.0 0.078 12.5 0.0 1.6 1 1 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 OAP63375.1 - 0.056 12.5 0.3 0.14 11.1 0.0 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein TrkA_N PF02254.18 OAP63375.1 - 0.077 13.3 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_9 PF13454.6 OAP63375.1 - 0.16 12.0 0.2 1.2 9.1 0.0 2.4 3 0 0 3 3 3 0 FAD-NAD(P)-binding Aim21 PF11489.8 OAP63376.1 - 6.4e-168 560.9 70.9 6.4e-168 560.9 70.9 2.5 2 1 0 2 2 2 1 Altered inheritance of mitochondria protein 21 Surp PF01805.20 OAP63377.1 - 2.1e-12 46.8 0.0 4e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 Surp module Tannase PF07519.11 OAP63378.1 - 3.7e-14 52.5 0.0 3.7e-14 52.5 0.0 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase PEPCK_GTP PF00821.18 OAP63378.1 - 0.052 12.4 0.0 0.067 12.0 0.0 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain MFS_1 PF07690.16 OAP63379.1 - 4.1e-17 62.1 5.9 6e-17 61.6 5.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily CoA_transf_3 PF02515.17 OAP63381.1 - 6.8e-29 101.1 0.0 4.3e-28 98.5 0.0 1.9 2 0 0 2 2 2 1 CoA-transferase family III GXWXG PF14231.6 OAP63381.1 - 0.062 13.4 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 GXWXG protein Methyltransf_PK PF05891.12 OAP63382.1 - 7.4e-55 185.8 0.0 2.8e-41 141.4 0.0 2.9 2 1 0 2 2 2 2 AdoMet dependent proline di-methyltransferase Methyltransf_23 PF13489.6 OAP63382.1 - 2.4e-05 24.2 0.0 3.4e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Auxin_repressed PF05564.12 OAP63382.1 - 0.0028 18.3 0.5 0.0065 17.1 0.5 1.6 1 0 0 1 1 1 1 Dormancy/auxin associated protein Period_C PF12114.8 OAP63382.1 - 0.98 9.0 9.2 1.6 8.3 9.2 1.2 1 0 0 1 1 1 0 Period protein 2/3C-terminal region RTA1 PF04479.13 OAP63383.1 - 4.3e-66 222.5 9.3 5.7e-66 222.1 9.3 1.2 1 0 0 1 1 1 1 RTA1 like protein NDUF_B12 PF08122.12 OAP63383.1 - 7.5 6.7 5.4 3.7 7.7 0.0 3.0 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase B12 subunit family adh_short PF00106.25 OAP63385.1 - 8.7e-29 100.4 0.0 1.2e-28 99.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP63385.1 - 3.5e-21 75.8 0.0 4.2e-21 75.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP63385.1 - 1.4e-05 25.1 0.1 1.8e-05 24.8 0.1 1.2 1 0 0 1 1 1 1 KR domain Lyase_1 PF00206.20 OAP63386.1 - 1.2e-47 162.8 0.0 2.3e-47 161.9 0.0 1.4 1 1 0 1 1 1 1 Lyase ADSL_C PF10397.9 OAP63386.1 - 5.1e-21 75.0 0.1 1.1e-19 70.7 0.1 2.5 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminus YkyA PF10368.9 OAP63386.1 - 0.098 12.3 0.6 0.17 11.6 0.1 1.5 2 0 0 2 2 2 0 Putative cell-wall binding lipoprotein TFIIB PF00382.19 OAP63387.1 - 2.9e-26 91.3 1.1 2.6e-17 62.6 0.0 2.8 3 0 0 3 3 3 2 Transcription factor TFIIB repeat BRF1 PF07741.13 OAP63387.1 - 1e-18 67.5 7.5 1e-18 67.5 7.5 5.3 5 1 0 5 5 5 1 Brf1-like TBP-binding domain mono-CXXC PF15626.6 OAP63390.1 - 2.1 8.7 4.9 1 9.8 1.2 2.6 2 0 0 2 2 2 0 single CXXC unit Myb_DNA-bind_6 PF13921.6 OAP63392.1 - 0.0098 16.1 0.1 0.15 12.3 0.0 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_3 PF12776.7 OAP63392.1 - 0.068 14.2 0.3 0.98 10.4 0.1 2.6 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain BTB PF00651.31 OAP63393.1 - 3.6e-09 36.8 0.1 1e-07 32.2 0.0 2.8 2 1 1 3 3 3 1 BTB/POZ domain Skp1_POZ PF03931.15 OAP63393.1 - 0.017 15.2 0.0 0.15 12.3 0.0 2.2 2 0 0 2 2 2 0 Skp1 family, tetramerisation domain ADH_N PF08240.12 OAP63395.1 - 7e-26 90.2 1.8 1.6e-25 89.1 1.8 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAP63395.1 - 5.8e-17 61.9 2.4 3.9e-12 46.3 0.6 2.6 3 0 0 3 3 3 2 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAP63395.1 - 0.00094 20.2 0.0 0.0025 18.9 0.0 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase DUF4453 PF14627.6 OAP63395.1 - 0.013 15.6 0.0 0.026 14.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4453) Amidinotransf PF02274.17 OAP63395.1 - 0.087 11.9 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Amidinotransferase CFEM PF05730.11 OAP63398.1 - 2.3e-10 40.4 7.2 2.3e-10 40.4 7.2 1.8 2 0 0 2 2 2 1 CFEM domain Cu-oxidase_2 PF07731.14 OAP63400.1 - 8e-42 142.2 2.9 1.9e-36 124.8 0.6 2.8 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 OAP63400.1 - 2.3e-36 124.4 7.4 2e-35 121.3 0.1 3.7 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase PF00394.22 OAP63400.1 - 2.2e-35 122.1 0.1 2.9e-30 105.5 0.0 2.9 3 0 0 3 3 3 2 Multicopper oxidase DUF4366 PF14283.6 OAP63400.1 - 0.25 11.4 0.0 0.43 10.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Fungal_trans PF04082.18 OAP63402.1 - 3.6e-09 36.0 0.0 9.1e-09 34.7 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Ferric_reduct PF01794.19 OAP63403.1 - 1.2e-15 57.8 12.5 3.4e-15 56.3 12.5 1.9 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 OAP63403.1 - 2.1e-08 34.2 0.2 5.5e-08 32.9 0.1 1.7 2 0 0 2 2 2 1 FAD-binding domain Fungal_trans PF04082.18 OAP63404.1 - 1.1e-20 73.9 0.2 2.8e-20 72.5 0.2 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP63404.1 - 8.7e-07 29.0 13.1 1.4e-06 28.3 13.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BCMA-Tall_bind PF09257.10 OAP63404.1 - 0.6 10.3 4.7 1.4 9.1 4.7 1.5 1 0 0 1 1 1 0 BCMA, TALL-1 binding Mannosidase_ig PF17786.1 OAP63405.1 - 1e-17 64.5 0.6 2.7e-17 63.2 0.6 1.8 1 0 0 1 1 1 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 OAP63405.1 - 2.3e-11 44.3 0.1 7.7e-11 42.6 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 NTP_transf_9 PF04248.12 OAP63406.1 - 4.7e-32 109.7 0.3 6e-32 109.4 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF427) Lact_bio_phlase PF09508.10 OAP63406.1 - 0.042 12.3 0.0 0.051 12.0 0.0 1.1 1 0 0 1 1 1 0 Lacto-N-biose phosphorylase N-terminal TIM barrel domain Sulf_transp PF04143.14 OAP63407.1 - 5.3e-34 118.2 28.2 1.2e-33 117.0 28.2 1.5 1 1 0 1 1 1 1 Sulphur transport FCH PF00611.23 OAP63409.1 - 6.9e-16 58.3 0.0 1.4e-15 57.3 0.0 1.6 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.28 OAP63409.1 - 1.2e-11 44.1 0.0 3.6e-11 42.5 0.0 1.9 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 OAP63409.1 - 9.4e-11 41.2 0.0 1.4e-09 37.4 0.0 2.5 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.6 OAP63409.1 - 2.4e-10 40.1 0.0 6.1e-10 38.8 0.0 1.7 2 0 0 2 2 2 1 Variant SH3 domain Rapsyn_N PF10579.9 OAP63409.1 - 0.076 13.1 0.1 0.17 12.0 0.1 1.6 1 0 0 1 1 1 0 Rapsyn N-terminal myristoylation and linker region Amdase PF17645.1 OAP63410.1 - 1.8e-15 57.2 0.5 2.1e-15 57.0 0.5 1.2 1 0 0 1 1 1 1 Arylmalonate decarboxylase Glyco_hydro_64 PF16483.5 OAP63411.1 - 1.8e-105 353.3 1.5 2e-105 353.1 1.5 1.0 1 0 0 1 1 1 1 Beta-1,3-glucanase NmrA PF05368.13 OAP63412.1 - 2.4e-37 128.7 0.1 2.9e-37 128.5 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAP63412.1 - 8.5e-18 64.9 0.2 1.1e-17 64.6 0.2 1.1 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAP63412.1 - 1.8e-06 27.6 0.0 2.6e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 OAP63412.1 - 7.9e-05 21.9 0.2 0.0012 18.0 0.1 2.1 1 1 1 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.19 OAP63412.1 - 0.003 16.6 0.0 0.0041 16.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 OAP63412.1 - 0.011 14.9 0.1 0.22 10.6 0.1 2.1 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein KR PF08659.10 OAP63412.1 - 0.018 15.0 0.5 0.055 13.4 0.3 1.9 1 1 1 2 2 2 0 KR domain DapB_N PF01113.20 OAP63412.1 - 0.045 13.9 0.2 0.14 12.2 0.2 1.9 1 1 1 2 2 2 0 Dihydrodipicolinate reductase, N-terminus adh_short PF00106.25 OAP63412.1 - 0.065 12.7 0.4 0.1 12.0 0.4 1.4 1 1 0 1 1 1 0 short chain dehydrogenase Zn_clus PF00172.18 OAP63413.1 - 0.0023 18.0 7.0 0.0069 16.5 7.0 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sulfatase PF00884.23 OAP63414.1 - 1.5e-73 247.9 0.0 1.9e-73 247.5 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 OAP63414.1 - 0.01 15.4 0.1 0.037 13.6 0.0 1.8 2 0 0 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase PSRT PF07636.11 OAP63414.1 - 0.2 11.3 1.2 0.51 10.0 1.2 1.7 1 0 0 1 1 1 0 PSRT Sugar_tr PF00083.24 OAP63415.1 - 6.7e-101 338.4 24.5 8.1e-101 338.1 24.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP63415.1 - 3.6e-23 82.1 25.8 3.6e-23 82.1 25.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.18 OAP63416.1 - 6.8e-15 54.8 0.0 1e-14 54.2 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF2457 PF10446.9 OAP63418.1 - 1.3 8.0 7.4 1.7 7.7 7.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DASH_Duo1 PF08651.10 OAP63419.1 - 5.5e-31 106.2 2.2 9.1e-31 105.5 2.2 1.4 1 0 0 1 1 1 1 DASH complex subunit Duo1 Flagellin_C PF00700.21 OAP63419.1 - 0.013 15.9 0.8 0.025 14.9 0.5 1.7 1 1 0 1 1 1 0 Bacterial flagellin C-terminal helical region API5 PF05918.11 OAP63419.1 - 0.044 12.6 8.9 0.053 12.3 8.9 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) DUF674 PF05056.12 OAP63419.1 - 0.044 12.6 0.1 0.059 12.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF674) DASH_Dad2 PF08654.10 OAP63419.1 - 0.46 10.9 12.7 0.62 10.5 10.8 2.2 1 1 1 2 2 2 0 DASH complex subunit Dad2 Macoilin PF09726.9 OAP63419.1 - 1.4 7.4 14.0 1.9 7.0 14.0 1.1 1 0 0 1 1 1 0 Macoilin family RR_TM4-6 PF06459.12 OAP63419.1 - 1.5 8.6 13.6 2 8.2 13.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Syntaxin-6_N PF09177.11 OAP63419.1 - 4.5 7.9 12.1 1.7 9.3 1.2 2.4 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DUF5302 PF17227.2 OAP63419.1 - 5.3 8.1 15.7 0.69 11.0 10.4 2.3 2 1 0 2 2 2 0 Family of unknown function (DUF5302) FAM76 PF16046.5 OAP63419.1 - 6.5 6.0 10.7 8.5 5.6 10.7 1.1 1 0 0 1 1 1 0 FAM76 protein ALMT PF11744.8 OAP63419.1 - 7.2 5.3 9.2 8.8 5.0 9.2 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Not1 PF04054.15 OAP63421.1 - 2.6e-97 326.1 0.0 1.5e-96 323.5 0.0 2.3 3 0 0 3 3 3 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 OAP63421.1 - 4e-92 307.7 1.8 1.3e-91 306.0 1.8 1.9 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain DUF3819 PF12842.7 OAP63421.1 - 6.2e-49 165.7 1.0 6.2e-49 165.7 1.0 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF3819) CNOT1_TTP_bind PF16417.5 OAP63421.1 - 2.9e-39 134.2 0.0 1.1e-38 132.3 0.0 1.9 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 TTP binding domain CNOT1_HEAT PF16418.5 OAP63421.1 - 8.1e-20 71.4 0.0 2.8e-19 69.7 0.0 2.0 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 HEAT repeat RSN1_7TM PF02714.15 OAP63422.1 - 3.6e-91 305.3 27.2 7.8e-91 304.2 25.0 2.3 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 OAP63422.1 - 2.9e-37 127.8 0.2 2.9e-37 127.8 0.2 3.0 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 OAP63422.1 - 1.1e-31 110.4 2.9 1.9e-31 109.7 2.9 1.4 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 OAP63422.1 - 8e-19 67.6 2.0 3e-18 65.8 0.4 2.3 2 0 0 2 2 2 1 Extracellular tail, of 10TM putative phosphate transporter 7tm_1 PF00001.21 OAP63422.1 - 0.0085 15.4 2.8 0.048 13.0 1.5 2.7 2 1 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) Seipin PF06775.14 OAP63423.1 - 5e-56 189.9 3.4 6.4e-56 189.6 3.4 1.1 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) Nop14 PF04147.12 OAP63423.1 - 2.1 6.5 3.9 2.9 6.0 3.9 1.1 1 0 0 1 1 1 0 Nop14-like family AMP-binding PF00501.28 OAP63424.1 - 2.9e-42 144.7 0.0 4.4e-42 144.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAP63424.1 - 2.1e-05 25.4 0.3 6e-05 23.9 0.1 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain E1-E2_ATPase PF00122.20 OAP63425.1 - 6.1e-51 172.5 0.1 1.1e-49 168.4 0.0 2.9 1 1 1 2 2 2 1 E1-E2 ATPase HMA PF00403.26 OAP63425.1 - 2.8e-43 146.2 0.2 6.6e-13 48.9 0.0 5.0 5 0 0 5 5 5 4 Heavy-metal-associated domain Hydrolase PF00702.26 OAP63425.1 - 1.1e-39 136.9 0.0 2.6e-39 135.7 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 OAP63425.1 - 0.00014 21.7 0.0 0.0099 15.6 0.1 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 OAP63425.1 - 0.0013 19.1 0.0 0.0054 17.1 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DAHP_snth_FXD PF18152.1 OAP63425.1 - 0.055 13.3 0.1 7.2 6.5 0.0 3.6 4 0 0 4 4 4 0 DAHP synthase ferredoxin-like domain PBP_like PF12727.7 OAP63425.1 - 0.15 11.2 0.0 0.32 10.1 0.0 1.4 1 0 0 1 1 1 0 PBP superfamily domain E3_UbLigase_EDD PF11547.8 OAP63425.1 - 0.15 11.7 0.8 0.53 10.0 0.5 2.1 2 0 0 2 2 2 0 E3 ubiquitin ligase EDD Ank_4 PF13637.6 OAP63425.1 - 0.18 12.4 0.0 1.5 9.5 0.0 2.5 2 0 0 2 2 2 0 Ankyrin repeats (many copies) PHD PF00628.29 OAP63426.1 - 2.8e-08 33.5 12.5 5.2e-08 32.7 12.5 1.4 1 0 0 1 1 1 1 PHD-finger zf-RING_7 PF02591.15 OAP63426.1 - 0.017 15.3 5.0 0.4 10.9 0.0 3.4 2 1 1 3 3 3 0 C4-type zinc ribbon domain C1_1 PF00130.22 OAP63426.1 - 0.049 13.5 13.8 0.22 11.4 8.4 2.3 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.6 OAP63426.1 - 0.15 11.7 10.1 0.39 10.3 10.1 1.8 1 1 0 1 1 1 0 PHD-finger AAA_12 PF13087.6 OAP63427.1 - 7.6e-31 107.3 0.0 1.8e-30 106.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 OAP63427.1 - 5.6e-19 68.9 0.0 1.6e-18 67.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OAP63427.1 - 3.5e-06 27.4 0.1 0.0054 17.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 OAP63427.1 - 0.00025 20.8 0.1 0.094 12.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 OAP63427.1 - 0.0042 16.9 0.1 5.5 6.7 0.0 3.3 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase PhoH PF02562.16 OAP63427.1 - 0.012 15.1 0.0 0.087 12.3 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein UvrD_C_2 PF13538.6 OAP63427.1 - 0.014 15.2 0.0 0.033 14.0 0.0 1.7 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain DUF2075 PF09848.9 OAP63427.1 - 0.045 13.0 0.0 1.4 8.1 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 OAP63427.1 - 0.081 12.9 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA PF00004.29 OAP63427.1 - 0.13 12.6 0.0 0.34 11.3 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) HTH_26 PF13443.6 OAP63427.1 - 0.16 12.4 1.3 0.61 10.6 0.7 2.3 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain ECH_1 PF00378.20 OAP63428.1 - 2.5e-37 128.6 0.0 3.3e-37 128.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAP63428.1 - 1.9e-25 90.1 0.0 2.1e-25 89.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase HET PF06985.11 OAP63429.1 - 8e-08 32.8 0.5 1.5e-05 25.3 0.0 2.6 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) SAC3_GANP PF03399.16 OAP63429.1 - 0.034 13.5 0.0 0.082 12.3 0.0 1.6 1 0 0 1 1 1 0 SAC3/GANP family MFS_1 PF07690.16 OAP63430.1 - 2.9e-46 158.0 37.6 2.9e-46 158.0 37.6 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 OAP63430.1 - 1e-07 31.6 7.6 1e-07 31.6 7.6 2.1 1 1 1 2 2 2 1 Uncharacterised MFS-type transporter YbfB Sugar_tr PF00083.24 OAP63430.1 - 1.1e-07 31.2 16.0 1.1e-07 31.2 16.0 2.8 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 OAP63430.1 - 1.7e-06 26.8 3.0 2.8e-06 26.1 3.0 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) AAA_12 PF13087.6 OAP63432.1 - 5e-41 140.5 0.0 1e-40 139.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 OAP63432.1 - 1.9e-26 93.4 0.1 4.6e-26 92.2 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OAP63432.1 - 3.8e-08 33.8 3.8 7.3e-08 32.9 0.0 3.4 4 1 0 4 4 4 1 AAA domain AAA_30 PF13604.6 OAP63432.1 - 1.4e-05 24.9 0.2 0.007 16.1 0.0 3.0 2 1 1 3 3 3 2 AAA domain DUF2075 PF09848.9 OAP63432.1 - 4.7e-05 22.8 0.0 0.29 10.3 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.18 OAP63432.1 - 6.2e-05 22.9 0.2 0.25 11.1 0.0 3.0 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.6 OAP63432.1 - 0.095 12.5 0.0 0.3 11.0 0.0 1.9 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain ResIII PF04851.15 OAP63432.1 - 0.13 12.3 0.0 0.45 10.5 0.0 1.9 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DZR PF12773.7 OAP63432.1 - 2.6 8.1 5.5 3.5 7.7 0.3 3.0 3 0 0 3 3 3 0 Double zinc ribbon zf-ribbon_3 PF13248.6 OAP63432.1 - 3.7 7.1 7.7 0.16 11.5 0.4 2.6 3 0 0 3 3 3 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 OAP63432.1 - 6.2 7.0 6.7 2.9 8.1 0.9 3.1 3 0 0 3 3 3 0 Zinc ribbon domain Tannase PF07519.11 OAP63433.1 - 2.1e-101 340.2 0.4 2.4e-101 340.0 0.4 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.21 OAP63433.1 - 2.8e-06 26.9 0.1 2.1e-05 24.1 0.1 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 OAP63433.1 - 2.1e-05 23.9 0.1 9e-05 21.9 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OAP63433.1 - 0.027 14.1 0.1 0.051 13.2 0.1 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold APH PF01636.23 OAP63434.1 - 2.2e-10 40.9 0.0 7.4e-09 35.9 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 OAP63434.1 - 5.2e-08 32.7 0.0 6.4e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 OAP63434.1 - 0.069 12.7 0.0 1.1 8.8 0.0 2.1 2 0 0 2 2 2 0 RIO1 family Pkinase PF00069.25 OAP63434.1 - 0.19 11.0 0.0 0.34 10.3 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain Fungal_trans PF04082.18 OAP63435.1 - 4.8e-27 94.7 0.0 7.4e-27 94.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP63435.1 - 1.3e-11 44.4 4.0 2.4e-11 43.6 4.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugarporin_N PF11471.8 OAP63435.1 - 0.12 12.4 0.0 0.35 10.9 0.0 1.8 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension p450 PF00067.22 OAP63436.1 - 1.6e-43 149.1 0.0 2.6e-43 148.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_3 PF01494.19 OAP63437.1 - 1.7e-23 83.5 0.0 2.1e-23 83.1 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAP63437.1 - 2.8e-10 40.3 1.1 9.3e-05 22.2 0.5 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAP63437.1 - 0.0025 18.0 0.5 0.0064 16.7 0.5 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 OAP63437.1 - 0.0035 16.2 2.3 1.2 7.9 0.9 2.2 2 0 0 2 2 2 2 Tryptophan halogenase Pyr_redox_2 PF07992.14 OAP63437.1 - 0.0051 16.1 1.1 0.023 14.0 0.3 2.0 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAP63437.1 - 0.0063 16.5 0.1 0.18 11.8 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding SE PF08491.10 OAP63437.1 - 0.07 12.2 0.0 3.7 6.5 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase AbrB_C PF18277.1 OAP63437.1 - 0.11 12.2 0.0 0.25 11.0 0.0 1.7 1 0 0 1 1 1 0 AbrB C-terminal domain Glyoxalase PF00903.25 OAP63438.1 - 5.6e-10 39.5 0.0 8.4e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 OAP63438.1 - 0.046 14.5 0.0 0.089 13.6 0.0 1.4 1 0 0 1 1 1 0 Glyoxalase-like domain Sugar_tr PF00083.24 OAP63439.1 - 6.6e-95 318.6 31.0 7.7e-95 318.4 31.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP63439.1 - 2.1e-22 79.5 35.6 6.7e-20 71.3 24.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.18 OAP63440.1 - 1.4e-18 66.9 0.0 2.5e-18 66.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP63440.1 - 1.4e-07 31.5 13.5 1.4e-07 31.5 13.5 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.26 OAP63440.1 - 1.8e-05 24.9 0.4 1.8e-05 24.9 0.4 2.3 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAP63440.1 - 0.00015 22.3 0.2 0.00015 22.3 0.2 2.8 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_11 PF16622.5 OAP63440.1 - 0.0011 18.6 0.1 0.004 16.9 0.1 2.0 1 0 0 1 1 1 1 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 OAP63440.1 - 0.029 14.3 0.0 0.029 14.3 0.0 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OAP63440.1 - 0.21 12.1 5.0 3.6 8.2 1.3 2.7 2 0 0 2 2 2 0 Zinc-finger double domain Ketoacyl-synt_C PF02801.22 OAP63443.1 - 1.9e-15 56.9 0.0 2.7e-15 56.4 0.0 1.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ketoacyl-synt PF00109.26 OAP63443.1 - 0.00067 19.3 0.0 0.00095 18.8 0.0 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KAsynt_C_assoc PF16197.5 OAP63443.1 - 0.16 12.5 0.2 0.35 11.4 0.2 1.5 1 0 0 1 1 1 0 Ketoacyl-synthetase C-terminal extension Ank_2 PF12796.7 OAP63444.1 - 5.9e-45 151.8 2.2 3.4e-08 33.9 0.0 7.8 3 1 6 9 9 9 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAP63444.1 - 1.2e-44 150.1 0.5 3.4e-08 33.9 0.0 8.8 3 2 6 9 9 9 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 OAP63444.1 - 1.5e-38 130.3 5.8 1.8e-06 28.1 0.0 8.6 5 2 3 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAP63444.1 - 5.6e-36 118.5 0.1 0.01 16.3 0.0 12.4 12 0 0 12 12 12 8 Ankyrin repeat Ank PF00023.30 OAP63444.1 - 5.3e-31 105.7 0.3 0.0031 17.9 0.0 11.2 11 2 0 11 11 11 7 Ankyrin repeat SPRY PF00622.28 OAP63444.1 - 7e-15 55.2 0.1 2.3e-14 53.5 0.1 2.0 1 0 0 1 1 1 1 SPRY domain NACHT PF05729.12 OAP63444.1 - 3.5e-06 27.0 0.1 7.5e-05 22.7 0.1 2.7 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 OAP63444.1 - 0.00081 19.8 0.4 0.0079 16.6 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain RNA_helicase PF00910.22 OAP63444.1 - 0.0053 17.1 0.1 0.73 10.2 0.0 3.2 3 0 0 3 3 3 1 RNA helicase TEX19 PF15553.6 OAP63444.1 - 2.2 8.2 8.1 0.79 9.7 3.4 2.6 1 1 1 2 2 2 0 Testis-expressed protein 19 LtrA PF06772.11 OAP63445.1 - 6.6e-44 150.6 18.8 8.1e-44 150.3 18.8 1.1 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) PSI PF01437.25 OAP63445.1 - 0.23 12.0 2.1 0.48 11.0 2.1 1.5 1 0 0 1 1 1 0 Plexin repeat RTC4 PF14474.6 OAP63446.1 - 2.1e-26 92.5 0.0 3.5e-26 91.8 0.0 1.4 1 0 0 1 1 1 1 RTC4-like domain zf-Di19 PF05605.12 OAP63446.1 - 0.19 12.1 0.0 0.36 11.2 0.0 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Stm1_N PF09598.10 OAP63446.1 - 8.9 7.2 9.8 0.87 10.5 0.7 2.5 2 0 0 2 2 2 0 Stm1 MIP PF00230.20 OAP63447.1 - 1.3e-30 106.8 5.6 1.7e-30 106.4 5.6 1.1 1 0 0 1 1 1 1 Major intrinsic protein CPP1-like PF11833.8 OAP63447.1 - 1.5 8.4 3.1 1.5 8.5 0.4 2.3 2 1 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like DctQ PF04290.12 OAP63447.1 - 9.6 6.1 11.7 0.48 10.3 5.7 1.9 2 0 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component zf-B_box PF00643.24 OAP63448.1 - 0.59 10.3 2.4 1 9.6 2.4 1.3 1 0 0 1 1 1 0 B-box zinc finger DUF2508 PF10704.9 OAP63448.1 - 1.2 9.3 3.2 8.5 6.6 0.3 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2508) Exonuc_VII_L PF02601.15 OAP63449.1 - 0.11 12.0 3.7 0.18 11.3 3.7 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Atg14 PF10186.9 OAP63450.1 - 2.2e-60 204.4 1.2 3.1e-60 203.9 1.2 1.1 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 DUF555 PF04475.12 OAP63450.1 - 0.08 13.3 0.1 0.19 12.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF555) zf-C3HC4_4 PF15227.6 OAP63450.1 - 0.21 11.8 2.0 0.43 10.8 2.0 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING PEP-utilisers_N PF05524.13 OAP63450.1 - 0.28 11.3 7.7 0.6 10.3 7.7 1.6 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal Exonuc_VII_L PF02601.15 OAP63450.1 - 1.4 8.4 10.5 2.2 7.8 10.5 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit FapA PF03961.13 OAP63450.1 - 1.5 7.4 7.8 2 6.9 7.8 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A HAUS-augmin3 PF14932.6 OAP63450.1 - 2.5 7.6 17.1 4.6 6.7 17.1 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 LMBR1 PF04791.16 OAP63450.1 - 3.6 6.4 5.8 4.9 5.9 5.8 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein UPF0242 PF06785.11 OAP63450.1 - 6.6 6.8 16.7 16 5.6 16.7 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF2401 PF10287.9 OAP63451.1 - 3.2e-89 298.5 0.0 4.8e-89 297.9 0.0 1.3 1 0 0 1 1 1 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.9 OAP63451.1 - 1.4e-23 83.0 0.2 1.4e-23 83.0 0.2 2.3 3 0 0 3 3 3 1 Glycine-rich protein domain (DUF2403) MFS_1 PF07690.16 OAP63452.1 - 1.2e-34 119.8 25.7 1.7e-34 119.3 25.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 OAP63452.1 - 5.2e-07 29.3 7.1 1.8e-06 27.5 4.2 2.2 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB Pkinase PF00069.25 OAP63453.1 - 2.1e-27 96.1 0.0 3.1e-27 95.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP63453.1 - 1.3e-13 50.9 0.0 2.2e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OAP63453.1 - 0.15 12.0 1.4 0.27 11.1 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pyr_redox_2 PF07992.14 OAP63454.1 - 1.6e-15 57.2 0.0 1.9e-14 53.6 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 OAP63454.1 - 1.1e-14 53.8 0.1 8.5e-13 47.6 0.0 2.2 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 OAP63454.1 - 3.6e-12 46.1 0.1 1e-09 38.0 0.0 2.4 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 OAP63454.1 - 1.1e-11 44.6 0.0 9.8e-10 38.2 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAP63454.1 - 2.9e-10 40.2 0.0 1.1e-07 32.0 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 OAP63454.1 - 1.6e-05 25.4 0.1 0.13 12.8 0.0 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAP63454.1 - 2.6e-05 24.3 0.3 0.38 10.7 0.1 4.2 3 1 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.24 OAP63454.1 - 3.8e-05 23.4 0.2 0.24 10.9 0.0 4.1 3 1 0 3 3 3 1 FAD dependent oxidoreductase HI0933_like PF03486.14 OAP63454.1 - 0.0015 17.3 0.3 0.12 11.0 0.1 2.9 3 0 0 3 3 3 1 HI0933-like protein Shikimate_DH PF01488.20 OAP63454.1 - 0.0025 17.9 0.0 0.032 14.3 0.0 2.2 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 OAP63454.1 - 0.0033 17.9 0.9 0.14 12.6 0.4 3.2 2 1 0 2 2 2 1 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.19 OAP63454.1 - 0.0034 16.7 0.0 0.0091 15.4 0.0 1.7 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GIDA PF01134.22 OAP63454.1 - 0.004 16.3 0.1 0.62 9.1 0.0 3.1 3 1 0 3 3 3 1 Glucose inhibited division protein A ApbA PF02558.16 OAP63454.1 - 0.0046 16.6 0.0 0.033 13.8 0.0 2.1 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA Thi4 PF01946.17 OAP63454.1 - 0.0051 16.1 0.3 0.076 12.3 0.0 2.5 3 0 0 3 3 3 1 Thi4 family FAD_oxidored PF12831.7 OAP63454.1 - 0.016 14.6 0.0 0.032 13.6 0.0 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OAP63454.1 - 0.017 14.2 0.0 0.03 13.4 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain NAD_binding_2 PF03446.15 OAP63454.1 - 0.032 14.4 0.0 0.1 12.8 0.0 1.8 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase DUF896 PF05979.12 OAP63454.1 - 0.06 13.2 2.1 0.53 10.2 0.1 2.9 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF896) 3HCDH_N PF02737.18 OAP63454.1 - 0.089 12.7 0.0 0.3 10.9 0.0 1.9 2 0 0 2 2 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 OAP63454.1 - 0.097 13.3 0.1 0.52 10.9 0.0 2.2 3 0 0 3 3 2 0 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.23 OAP63454.1 - 0.17 11.8 0.0 0.28 11.1 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Aminotran_1_2 PF00155.21 OAP63455.1 - 1.6e-14 53.9 0.0 2.4e-14 53.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 OAP63455.1 - 2.4e-05 23.3 0.0 8.8e-05 21.5 0.0 1.7 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase DegT_DnrJ_EryC1 PF01041.17 OAP63455.1 - 0.0012 18.2 0.0 0.0088 15.4 0.0 2.0 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family CBFD_NFYB_HMF PF00808.23 OAP63456.1 - 8.8e-30 102.8 1.0 1.2e-29 102.3 1.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 OAP63456.1 - 6.6e-06 26.5 0.0 1.1e-05 25.8 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.16 OAP63456.1 - 0.00079 19.4 0.0 0.0011 18.9 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.13 OAP63456.1 - 0.0014 18.6 0.1 0.0022 18.0 0.1 1.3 1 0 0 1 1 1 1 Bromodomain associated CENP-T_C PF15511.6 OAP63456.1 - 0.0037 17.3 0.0 0.005 16.9 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIID_20kDa PF03847.13 OAP63456.1 - 0.054 14.0 0.1 0.099 13.1 0.1 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A SH3_9 PF14604.6 OAP63458.1 - 1.9e-29 101.2 2.2 1.4e-13 50.4 0.2 2.6 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 OAP63458.1 - 1e-28 98.7 1.8 4.5e-14 51.8 0.2 2.5 2 0 0 2 2 2 2 SH3 domain Cofilin_ADF PF00241.20 OAP63458.1 - 2e-14 53.5 0.0 3.3e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein SH3_2 PF07653.17 OAP63458.1 - 2.1e-14 52.9 0.0 1.5e-06 27.7 0.0 3.0 3 0 0 3 3 3 2 Variant SH3 domain SH3_10 PF17902.1 OAP63458.1 - 0.0063 16.6 0.0 0.014 15.5 0.0 1.5 1 0 0 1 1 1 1 SH3 domain CPSase_L_D2 PF02786.17 OAP63459.1 - 1.2e-110 368.0 0.0 2.4e-84 282.1 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 OAP63459.1 - 7.4e-39 132.9 0.1 1.8e-38 131.6 0.1 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp PF02222.22 OAP63459.1 - 1.2e-19 70.5 0.1 1.1e-08 34.9 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.13 OAP63459.1 - 1.2e-17 64.2 0.8 6.7e-08 32.3 0.3 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 OAP63459.1 - 2.6e-12 46.6 0.0 1.5e-05 24.7 0.0 2.8 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon GARS_A PF01071.19 OAP63459.1 - 1.8e-05 24.6 0.2 0.021 14.6 0.1 2.8 3 0 0 3 3 3 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_5 PF13549.6 OAP63459.1 - 2.8e-05 23.7 0.1 0.067 12.6 0.1 3.0 3 0 0 3 3 3 2 ATP-grasp domain MGS PF02142.22 OAP63459.1 - 0.0027 17.8 0.0 0.013 15.7 0.0 2.2 2 0 0 2 2 2 1 MGS-like domain Epimerase PF01370.21 OAP63459.1 - 0.0076 15.7 0.0 0.027 13.9 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.10 OAP63459.1 - 0.12 12.3 0.0 0.39 10.6 0.0 1.8 1 0 0 1 1 1 0 KR domain DUF5333 PF17267.2 OAP63459.1 - 0.18 12.0 0.1 0.71 10.1 0.0 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5333) Fungal_trans PF04082.18 OAP63460.1 - 1.2e-23 83.5 0.1 1.9e-23 82.8 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP63460.1 - 1.6e-06 28.2 11.6 3e-06 27.2 11.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UAA PF08449.11 OAP63461.1 - 1.1e-79 267.8 0.7 1.4e-79 267.5 0.7 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 OAP63461.1 - 1.3e-05 25.4 20.9 0.0017 18.5 2.6 3.4 3 1 0 3 3 3 2 EamA-like transporter family TPT PF03151.16 OAP63461.1 - 0.031 13.6 3.5 0.37 10.1 1.2 2.3 2 0 0 2 2 2 0 Triose-phosphate Transporter family Se-cys_synth_N PF12390.8 OAP63461.1 - 0.091 13.0 0.0 0.23 11.7 0.0 1.7 1 0 0 1 1 1 0 Selenocysteine synthase N terminal AAA PF00004.29 OAP63462.1 - 1.1e-50 171.4 0.0 2.4e-42 144.5 0.0 3.3 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OAP63462.1 - 1.3e-10 40.9 0.0 4.9e-10 39.0 0.0 2.0 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 OAP63462.1 - 5.3e-08 33.4 0.3 3.6e-05 24.2 0.0 3.8 2 1 1 3 3 3 1 AAA ATPase domain IstB_IS21 PF01695.17 OAP63462.1 - 4.9e-07 29.6 0.0 2.8e-06 27.2 0.0 2.1 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_2 PF07724.14 OAP63462.1 - 8.5e-06 26.0 0.0 2.3e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Sigma54_activ_2 PF14532.6 OAP63462.1 - 0.00034 20.7 0.0 1.2 9.3 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_5 PF07728.14 OAP63462.1 - 0.00049 20.1 0.0 0.0018 18.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 OAP63462.1 - 0.00061 20.1 0.0 0.0048 17.3 0.0 2.5 3 0 0 3 3 2 1 RNA helicase Bromodomain PF00439.25 OAP63462.1 - 0.0013 18.8 0.0 0.0033 17.5 0.0 1.6 1 0 0 1 1 1 1 Bromodomain AAA_22 PF13401.6 OAP63462.1 - 0.0025 18.1 2.0 0.067 13.5 0.2 3.8 4 1 0 4 4 4 1 AAA domain AAA_25 PF13481.6 OAP63462.1 - 0.0027 17.3 0.0 0.0069 16.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 OAP63462.1 - 0.004 17.2 0.0 0.02 14.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 OAP63462.1 - 0.0047 17.4 0.2 0.03 14.8 0.0 2.5 2 0 0 2 2 2 1 ABC transporter Sigma54_activat PF00158.26 OAP63462.1 - 0.005 16.6 0.0 1.2 8.8 0.0 2.9 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_30 PF13604.6 OAP63462.1 - 0.0054 16.5 0.0 0.034 13.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain Torsin PF06309.11 OAP63462.1 - 0.0063 16.6 0.0 1.3 9.1 0.0 2.4 2 0 0 2 2 2 1 Torsin TIP49 PF06068.13 OAP63462.1 - 0.0064 15.7 0.0 0.011 14.9 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 OAP63462.1 - 0.011 15.9 0.1 0.051 13.7 0.0 2.2 2 0 0 2 2 1 0 AAA domain Mg_chelatase PF01078.21 OAP63462.1 - 0.027 13.8 0.1 0.076 12.4 0.1 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 OAP63462.1 - 0.037 13.9 1.1 0.15 12.0 0.0 2.6 3 0 0 3 3 2 0 NACHT domain RuvB_N PF05496.12 OAP63462.1 - 0.045 13.5 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 OAP63462.1 - 0.048 14.2 1.9 0.21 12.2 0.0 3.1 4 0 0 4 4 2 0 AAA domain AAA_7 PF12775.7 OAP63462.1 - 0.089 12.3 0.0 0.23 11.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region Parvo_NS1 PF01057.17 OAP63462.1 - 0.091 11.8 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_28 PF13521.6 OAP63462.1 - 0.092 13.0 0.0 0.37 11.0 0.0 2.1 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 OAP63462.1 - 0.094 12.1 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_3 PF07726.11 OAP63462.1 - 0.15 11.9 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 OAP63462.1 - 0.52 10.1 0.0 0.52 10.1 0.0 4.3 3 1 0 3 3 2 0 AAA domain PIEZO PF15917.5 OAP63462.1 - 0.54 9.7 7.1 2.1 7.7 0.1 3.0 2 0 0 2 2 2 0 Piezo DUF3336 PF11815.8 OAP63463.1 - 4e-48 162.6 1.0 6.2e-48 162.0 1.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 OAP63463.1 - 9.3e-18 65.1 0.1 1.8e-16 61.0 0.1 2.6 1 1 0 1 1 1 1 Patatin-like phospholipase SAT PF16073.5 OAP63463.1 - 0.16 11.7 0.8 0.66 9.7 0.8 1.8 1 1 0 1 1 1 0 Starter unit:ACP transacylase in aflatoxin biosynthesis DUF89 PF01937.19 OAP63463.1 - 0.17 10.8 0.0 0.28 10.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF89 LRR_4 PF12799.7 OAP63464.1 - 4.3e-13 49.2 10.8 0.00038 20.8 0.9 5.1 2 1 4 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OAP63464.1 - 4.9e-10 39.0 17.7 7e-08 32.1 3.9 4.5 4 1 1 5 5 5 3 Leucine rich repeat LRR_9 PF14580.6 OAP63464.1 - 4.1e-05 23.1 2.9 0.12 11.9 0.4 2.5 1 1 1 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.6 OAP63464.1 - 0.0021 17.9 12.3 5.4 7.3 0.5 5.3 5 0 0 5 5 5 3 Leucine Rich repeat LRR_1 PF00560.33 OAP63464.1 - 0.0029 17.9 8.6 7.9 7.5 0.9 5.9 7 0 0 7 7 7 2 Leucine Rich Repeat Metallophos PF00149.28 OAP63465.1 - 4e-40 138.5 0.1 5.2e-40 138.1 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 OAP63465.1 - 1.2e-21 76.8 1.1 2.1e-21 76.1 0.6 1.7 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain Arf PF00025.21 OAP63466.1 - 1.1e-64 217.1 0.0 1.3e-64 216.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 OAP63466.1 - 5e-10 39.1 0.0 1.9e-06 27.3 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 OAP63466.1 - 1.4e-07 31.6 0.0 1.9e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 OAP63466.1 - 1.9e-07 30.7 0.0 2.5e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 OAP63466.1 - 6.6e-07 29.6 0.0 1.7e-06 28.2 0.0 1.6 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 OAP63466.1 - 3.1e-05 23.6 0.0 4.1e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 OAP63466.1 - 0.00033 20.1 0.0 0.00037 19.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region cobW PF02492.19 OAP63466.1 - 0.034 13.8 0.0 1.8 8.1 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain GTP_EFTU PF00009.27 OAP63466.1 - 0.15 11.6 0.0 6.1 6.3 0.0 2.0 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain ACT PF01842.25 OAP63466.1 - 0.19 11.6 0.0 0.35 10.7 0.0 1.5 1 0 0 1 1 1 0 ACT domain DUF2457 PF10446.9 OAP63467.1 - 1e-140 470.0 20.0 1e-140 470.0 20.0 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF2457) FAA_hydrolase PF01557.18 OAP63469.1 - 6e-54 183.0 0.0 8.3e-54 182.5 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Ca_chan_IQ PF08763.11 OAP63469.1 - 0.19 12.0 0.0 0.35 11.1 0.0 1.4 1 0 0 1 1 1 0 Voltage gated calcium channel IQ domain Glyoxalase PF00903.25 OAP63470.1 - 5.3e-06 26.7 3.8 4.7e-05 23.6 1.7 2.8 2 1 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 OAP63470.1 - 0.12 12.6 0.2 0.76 10.1 0.2 2.4 2 1 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Rdx PF10262.9 OAP63471.1 - 9.4e-33 112.2 0.0 1.4e-32 111.7 0.0 1.2 1 0 0 1 1 1 1 Rdx family Fungal_trans PF04082.18 OAP63472.1 - 0.038 13.0 0.0 0.042 12.9 0.0 1.1 1 0 0 1 1 1 0 Fungal specific transcription factor domain DDT PF02791.17 OAP63472.1 - 0.091 13.1 0.1 0.3 11.4 0.0 1.8 2 0 0 2 2 2 0 DDT domain G-gamma PF00631.22 OAP63474.1 - 1.3e-20 73.1 0.1 2.5e-20 72.2 0.1 1.4 1 0 0 1 1 1 1 GGL domain ADIP PF11559.8 OAP63474.1 - 1.4 9.0 6.9 4.9 7.2 3.5 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Peptidase_S49_N PF08496.10 OAP63474.1 - 1.6 8.8 5.0 0.51 10.4 2.4 1.4 2 0 0 2 2 2 0 Peptidase family S49 N-terminal CHASE3 PF05227.13 OAP63474.1 - 2.2 8.2 7.0 0.41 10.6 3.4 1.5 2 0 0 2 2 2 0 CHASE3 domain PCI PF01399.27 OAP63475.1 - 2.4e-10 40.9 5.4 4.5e-10 40.0 0.0 3.4 3 0 0 3 3 3 1 PCI domain SRR1 PF07985.12 OAP63477.1 - 2.1e-06 27.7 0.0 3.8e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 SRR1 Acetyltransf_3 PF13302.7 OAP63478.1 - 1e-09 39.2 0.0 2.3e-09 38.0 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain KGG PF10685.9 OAP63479.1 - 9.5e-26 89.3 17.0 9.4e-11 41.6 1.0 3.1 3 0 0 3 3 3 3 Stress-induced bacterial acidophilic repeat motif MFS_1 PF07690.16 OAP63480.1 - 5.2e-29 101.3 35.1 5.2e-29 101.3 35.1 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Cyclin PF08613.11 OAP63480.1 - 0.067 13.6 0.2 0.11 12.9 0.2 1.3 1 0 0 1 1 1 0 Cyclin DUF1129 PF06570.11 OAP63480.1 - 9 5.7 6.3 4 6.9 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) FAA_hydrolase PF01557.18 OAP63481.1 - 2.4e-60 203.9 0.0 3e-60 203.6 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Fungal_trans PF04082.18 OAP63482.1 - 4.8e-35 120.9 0.2 8.1e-35 120.1 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP63482.1 - 1.7e-10 40.9 4.5 2.8e-10 40.1 4.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Lactamase_B PF00753.27 OAP63483.1 - 1.1e-10 41.9 0.9 2.8e-10 40.5 0.9 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OAP63483.1 - 0.0012 18.3 0.8 0.0043 16.6 0.1 2.1 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 OAP63483.1 - 0.072 13.0 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Amidohydro_2 PF04909.14 OAP63484.1 - 1.5e-39 136.5 0.0 1.8e-39 136.3 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase TatD_DNase PF01026.21 OAP63484.1 - 0.12 11.7 0.0 0.19 11.0 0.0 1.6 1 0 0 1 1 1 0 TatD related DNase MFS_1 PF07690.16 OAP63485.1 - 1.6e-33 116.1 33.4 2.3e-32 112.3 26.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DctQ PF04290.12 OAP63485.1 - 9.7 6.1 19.0 0.6 10.0 0.1 4.1 2 1 1 3 3 3 0 Tripartite ATP-independent periplasmic transporters, DctQ component ADH_zinc_N PF00107.26 OAP63486.1 - 1.6e-27 96.0 0.3 2.5e-27 95.4 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAP63486.1 - 4.6e-19 68.3 1.1 1.1e-18 67.1 0.8 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 OAP63486.1 - 1.3e-07 32.8 0.0 2.8e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 OAP63486.1 - 0.007 15.8 0.5 0.015 14.7 0.5 1.6 1 1 0 1 1 1 1 short chain dehydrogenase RPN6_C_helix PF18503.1 OAP63486.1 - 0.069 12.9 0.3 0.15 11.9 0.0 1.7 2 0 0 2 2 2 0 26S proteasome subunit RPN6 C-terminal helix domain DUF1180 PF06679.12 OAP63487.1 - 0.00046 20.6 0.3 0.001 19.5 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1180) SPX PF03105.19 OAP63487.1 - 0.021 14.8 0.1 0.021 14.8 0.1 1.1 1 0 0 1 1 1 0 SPX domain LapA_dom PF06305.11 OAP63487.1 - 0.027 14.3 0.7 0.05 13.4 0.7 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain DUF2207 PF09972.9 OAP63487.1 - 0.036 12.8 0.0 0.045 12.5 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) TraL PF07178.11 OAP63487.1 - 0.065 13.7 0.9 0.3 11.6 0.3 2.1 2 0 0 2 2 2 0 TraL protein CD34_antigen PF06365.12 OAP63487.1 - 0.066 12.8 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family DUF4448 PF14610.6 OAP63487.1 - 0.07 12.9 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Tmemb_cc2 PF10267.9 OAP63487.1 - 2.8 7.0 5.4 3.8 6.5 5.4 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein RAP1 PF07218.11 OAP63487.1 - 4.7 5.4 13.4 5.8 5.1 13.4 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Macoilin PF09726.9 OAP63487.1 - 6.2 5.3 5.7 8.1 4.9 5.7 1.1 1 0 0 1 1 1 0 Macoilin family SR-25 PF10500.9 OAP63487.1 - 7.3 6.1 16.5 11 5.5 16.5 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Patatin PF01734.22 OAP63488.1 - 1.2e-26 94.2 0.0 3.7e-26 92.6 0.0 1.8 1 1 0 1 1 1 1 Patatin-like phospholipase DUF1779 PF08680.10 OAP63488.1 - 0.26 11.4 1.0 0.57 10.3 0.2 1.9 2 0 0 2 2 2 0 TATA-box binding FAD_binding_3 PF01494.19 OAP63489.1 - 4.3e-14 52.5 0.0 8.9e-14 51.5 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAP63489.1 - 6.2e-11 42.5 1.6 0.00025 20.7 1.9 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAP63489.1 - 1.5e-09 37.5 0.3 1e-05 25.0 0.3 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAP63489.1 - 3.8e-09 36.6 0.1 8.1e-09 35.6 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 OAP63489.1 - 1e-07 31.5 0.8 2.2e-07 30.4 0.8 1.6 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.24 OAP63489.1 - 5.7e-07 29.2 0.5 0.0076 15.6 0.1 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase HI0933_like PF03486.14 OAP63489.1 - 4.2e-06 25.7 0.6 0.00015 20.7 0.3 2.1 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 OAP63489.1 - 1.4e-05 24.6 0.0 2e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 OAP63489.1 - 5.4e-05 22.5 0.4 0.00033 19.9 0.4 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A Trp_halogenase PF04820.14 OAP63489.1 - 7.3e-05 21.8 3.0 0.014 14.3 0.0 2.3 1 1 0 2 2 2 2 Tryptophan halogenase Pyr_redox PF00070.27 OAP63489.1 - 0.00014 22.3 0.1 0.00077 20.0 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OAP63489.1 - 0.0016 17.6 0.4 1.1 8.3 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein Thi4 PF01946.17 OAP63489.1 - 0.0025 17.1 0.0 0.005 16.1 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 OAP63489.1 - 0.0098 15.2 0.0 0.029 13.6 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAP63489.1 - 0.047 13.7 0.5 0.32 11.0 0.5 2.3 1 1 0 1 1 1 0 FAD-NAD(P)-binding MCRA PF06100.11 OAP63489.1 - 0.057 12.2 0.1 0.11 11.3 0.1 1.4 1 0 0 1 1 1 0 MCRA family AlaDh_PNT_C PF01262.21 OAP63489.1 - 0.14 11.4 0.5 0.38 10.0 0.5 1.7 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 OAP63489.1 - 0.26 11.1 2.4 0.28 11.0 0.4 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Cupin_2 PF07883.11 OAP63490.1 - 2.7e-24 84.7 0.5 3.7e-16 58.6 0.1 2.3 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.19 OAP63490.1 - 3e-07 30.4 0.2 0.0095 15.8 0.1 2.3 2 0 0 2 2 2 2 AraC-like ligand binding domain Cupin_3 PF05899.12 OAP63490.1 - 2.6e-06 27.0 0.0 0.027 14.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) CENP-C_C PF11699.8 OAP63490.1 - 3.3e-05 24.0 0.0 0.00018 21.6 0.0 1.9 2 0 0 2 2 2 1 Mif2/CENP-C like Cupin_1 PF00190.22 OAP63490.1 - 0.0081 15.8 0.1 0.53 9.9 0.0 2.2 2 0 0 2 2 2 1 Cupin ARD PF03079.14 OAP63490.1 - 0.035 14.3 0.0 0.21 11.7 0.0 2.2 3 0 0 3 3 3 0 ARD/ARD' family SPT2 PF08243.11 OAP63491.1 - 7e-07 29.8 18.5 7e-07 29.8 18.5 2.2 2 1 0 2 2 2 1 SPT2 chromatin protein Ribosomal_60s PF00428.19 OAP63492.1 - 3.8e-26 91.5 11.1 4.5e-26 91.2 11.1 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Cytomega_UL84 PF06284.11 OAP63492.1 - 0.047 12.1 1.5 0.053 12.0 1.5 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein RibD_C PF01872.17 OAP63492.1 - 0.13 12.0 0.0 0.19 11.5 0.0 1.2 1 0 0 1 1 1 0 RibD C-terminal domain DUF3824 PF12868.7 OAP63492.1 - 0.38 11.4 2.9 0.53 10.9 2.9 1.1 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) Ribosomal_S19 PF00203.21 OAP63493.1 - 4.4e-34 116.2 0.2 6.1e-34 115.8 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 DUF4187 PF13821.6 OAP63495.1 - 8.6e-22 76.7 2.7 2.1e-21 75.4 2.7 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.23 OAP63495.1 - 5.6e-09 35.8 0.2 1.3e-08 34.6 0.2 1.7 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 OAP63495.1 - 0.13 12.3 0.4 0.13 12.3 0.4 2.6 3 1 0 3 3 3 0 G-patch domain DUF732 PF05305.14 OAP63495.1 - 0.32 11.4 1.4 0.47 10.9 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF732) DUF3533 PF12051.8 OAP63496.1 - 1.1e-105 353.7 2.4 1.3e-105 353.4 2.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) ABC2_membrane_3 PF12698.7 OAP63496.1 - 1.6 7.8 11.4 4.5 6.3 11.4 1.8 1 1 0 1 1 1 0 ABC-2 family transporter protein Nop14 PF04147.12 OAP63497.1 - 3.8e-268 892.3 24.0 4.5e-268 892.1 24.0 1.0 1 0 0 1 1 1 1 Nop14-like family Noc2 PF03715.13 OAP63497.1 - 0.025 13.8 0.0 0.065 12.5 0.0 1.7 1 0 0 1 1 1 0 Noc2p family adh_short PF00106.25 OAP63498.1 - 9.5e-38 129.6 0.1 1.3e-37 129.1 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP63498.1 - 1.1e-24 87.3 0.1 1.5e-24 86.9 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 OAP63498.1 - 1.3e-07 31.3 0.1 2.1e-07 30.6 0.1 1.5 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) KR PF08659.10 OAP63498.1 - 3.1e-07 30.5 0.1 5.7e-07 29.6 0.1 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 OAP63498.1 - 0.00013 22.0 0.1 0.00019 21.4 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAP63498.1 - 0.0054 16.2 0.3 0.035 13.6 0.2 2.2 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 OAP63498.1 - 0.0078 15.8 0.2 0.014 15.0 0.2 1.4 1 0 0 1 1 1 1 NmrA-like family ADH_zinc_N PF00107.26 OAP63498.1 - 0.014 15.4 0.1 0.034 14.1 0.1 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase GntP_permease PF02447.16 OAP63498.1 - 0.022 13.5 0.1 0.028 13.1 0.1 1.1 1 0 0 1 1 1 0 GntP family permease ApbA PF02558.16 OAP63498.1 - 0.087 12.5 0.3 0.43 10.2 0.1 2.2 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 OAP63498.1 - 0.12 12.6 0.0 0.24 11.7 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Eno-Rase_NADH_b PF12242.8 OAP63498.1 - 0.19 11.5 0.4 0.41 10.4 0.1 1.7 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Sec66 PF09802.9 OAP63499.1 - 2.2e-68 229.4 0.0 2.7e-68 229.1 0.0 1.1 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 DUF4407 PF14362.6 OAP63499.1 - 0.0079 15.6 2.5 0.011 15.2 2.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) TPR_MLP1_2 PF07926.12 OAP63499.1 - 0.058 13.5 0.6 0.058 13.5 0.6 1.9 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Med3 PF11593.8 OAP63499.1 - 1.4 8.0 5.7 1.8 7.7 5.7 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal PPR_2 PF13041.6 OAP63500.1 - 2.9e-06 27.4 0.0 0.28 11.4 0.0 5.2 4 1 1 5 5 5 2 PPR repeat family Herpes_UL49_2 PF04823.12 OAP63500.1 - 0.091 12.9 0.9 0.23 11.6 0.1 2.1 2 0 0 2 2 2 0 Herpesvirus UL49 tegument protein HET PF06985.11 OAP63501.1 - 9.6e-05 22.8 0.3 0.0019 18.5 0.0 2.4 1 1 1 2 2 2 1 Heterokaryon incompatibility protein (HET) ORC_WH_C PF18137.1 OAP63502.1 - 3.6e-33 114.6 0.1 4.9e-32 110.9 0.0 2.6 3 0 0 3 3 3 1 Origin recognition complex winged helix C-terminal ORC3_N PF07034.11 OAP63502.1 - 2.6e-18 66.2 3.6 2.6e-18 66.2 3.6 2.7 2 1 0 2 2 2 1 Origin recognition complex (ORC) subunit 3 N-terminus Sigma70_ner PF04546.13 OAP63502.1 - 0.034 14.0 4.7 0.097 12.5 4.7 1.7 1 0 0 1 1 1 0 Sigma-70, non-essential region Voldacs PF03517.13 OAP63502.1 - 0.053 13.6 2.6 0.11 12.6 2.6 1.4 1 0 0 1 1 1 0 Regulator of volume decrease after cellular swelling TRAP_alpha PF03896.16 OAP63502.1 - 0.057 12.6 1.3 0.097 11.9 1.3 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit PBP1_TM PF14812.6 OAP63502.1 - 0.13 12.7 7.7 0.38 11.2 7.7 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CDC45 PF02724.14 OAP63502.1 - 0.29 9.4 5.6 0.55 8.5 5.6 1.4 1 0 0 1 1 1 0 CDC45-like protein TLP-20 PF06088.11 OAP63502.1 - 0.34 10.8 4.5 0.75 9.7 4.5 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) DUF4611 PF15387.6 OAP63502.1 - 4.9 7.4 10.3 4.5 7.5 7.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) zf-C2H2_aberr PF17017.5 OAP63503.1 - 2.3e-05 24.6 1.6 2.3e-05 24.6 1.6 3.0 2 1 1 3 3 3 1 Aberrant zinc-finger zf-H2C2_5 PF13909.6 OAP63503.1 - 0.00064 19.4 0.4 0.00064 19.4 0.4 5.8 6 0 0 6 6 6 2 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 OAP63503.1 - 0.0055 17.1 6.2 0.036 14.5 1.2 8.1 8 1 0 8 8 8 3 Zinc finger, C2H2 type FOXP-CC PF16159.5 OAP63503.1 - 0.12 13.0 0.1 0.12 13.0 0.1 5.6 3 2 3 6 6 6 0 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 OAP63503.1 - 3.4 8.0 11.1 6 7.2 0.3 3.8 2 1 1 3 3 3 0 C2H2-type zinc ribbon zf-C2H2 PF00096.26 OAP63504.1 - 0.35 11.4 28.5 0.96 10.0 0.7 4.8 4 0 0 4 4 4 0 Zinc finger, C2H2 type FOXP-CC PF16159.5 OAP63504.1 - 3.5 8.3 13.7 0.65 10.7 1.1 3.1 2 1 1 3 3 3 0 FOXP coiled-coil domain DUF3456 PF11938.8 OAP63505.1 - 0.008 16.7 3.1 0.008 16.7 3.1 3.4 3 1 0 3 3 3 1 TLR4 regulator and MIR-interacting MSAP COMP PF11598.8 OAP63505.1 - 2.4 8.7 6.2 0.57 10.7 0.8 2.9 2 1 1 3 3 3 0 Cartilage oligomeric matrix protein Filament PF00038.21 OAP63505.1 - 5.9 6.4 63.5 0.12 12.0 10.0 3.0 1 1 1 2 2 2 0 Intermediate filament protein ApoO PF09769.9 OAP63505.1 - 6.8 6.7 8.5 1.3 9.0 0.2 3.2 2 1 1 3 3 3 0 Apolipoprotein O DUF3999 PF13163.6 OAP63506.1 - 0.068 12.4 0.0 0.094 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3999) Carb_kinase PF01256.17 OAP63507.1 - 4e-52 177.1 0.0 5.4e-52 176.7 0.0 1.2 1 0 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.12 OAP63507.1 - 0.18 11.1 0.1 0.43 9.9 0.0 1.6 1 1 0 1 1 1 0 Phosphomethylpyrimidine kinase DUF2274 PF10038.9 OAP63507.1 - 0.19 12.2 0.1 1.3 9.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2274) Epimerase PF01370.21 OAP63508.1 - 4.7e-14 52.4 0.0 6e-14 52.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OAP63508.1 - 1.5e-08 34.0 0.0 2.4e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 OAP63508.1 - 2.2e-07 30.9 0.0 3.7e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 OAP63508.1 - 0.00067 18.9 0.0 0.042 13.0 0.0 2.0 2 0 0 2 2 2 2 Male sterility protein NmrA PF05368.13 OAP63508.1 - 0.02 14.4 0.0 0.028 14.0 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family GDP_Man_Dehyd PF16363.5 OAP63508.1 - 0.023 14.1 0.0 0.03 13.7 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase adh_short PF00106.25 OAP63508.1 - 0.035 13.6 0.7 0.76 9.2 0.3 2.7 2 1 0 2 2 2 0 short chain dehydrogenase DUF3807 PF12720.7 OAP63509.1 - 2e-26 93.4 1.4 2.5e-26 93.1 1.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3807) GOLD_2 PF13897.6 OAP63510.1 - 0.24 11.9 0.3 0.24 11.9 0.3 1.7 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking E1-E2_ATPase PF00122.20 OAP63511.1 - 1.4e-36 125.8 6.1 5.1e-36 123.9 0.1 3.6 4 0 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 OAP63511.1 - 5.6e-16 59.5 0.0 1.5e-15 58.1 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 OAP63511.1 - 5.9e-11 41.9 0.0 1.2e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 OAP63511.1 - 0.0023 18.0 0.0 0.0048 17.0 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 OAP63511.1 - 0.0032 17.3 0.1 0.0058 16.4 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Abhydrolase_3 PF07859.13 OAP63513.1 - 8.1e-40 136.9 0.0 8.2e-38 130.4 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 OAP63513.1 - 2.8e-08 33.1 0.0 1.4e-07 30.8 0.0 1.8 1 1 0 1 1 1 1 Carboxylesterase family tRNA-synt_2 PF00152.20 OAP63514.1 - 4.6e-71 239.5 0.0 7e-71 238.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.9 OAP63514.1 - 7.5e-17 61.3 0.0 1.4e-16 60.4 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2156) tRNA_anti-codon PF01336.25 OAP63514.1 - 0.011 15.6 0.1 0.024 14.6 0.1 1.5 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain MCM_N PF14551.6 OAP63514.1 - 0.018 15.6 0.1 0.07 13.7 0.1 2.0 1 0 0 1 1 1 0 MCM N-terminal domain tRNA-synt_2d PF01409.20 OAP63514.1 - 0.025 14.0 0.4 4.9 6.6 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) WLM PF08325.10 OAP63515.1 - 4.1e-59 199.9 0.1 1.9e-58 197.7 0.0 1.9 2 0 0 2 2 2 1 WLM domain zf-RanBP PF00641.18 OAP63515.1 - 0.00029 20.1 0.3 0.00029 20.1 0.3 3.0 3 0 0 3 3 3 2 Zn-finger in Ran binding protein and others DZR PF12773.7 OAP63515.1 - 0.27 11.3 6.1 3.2 7.8 5.3 2.5 2 1 0 2 2 2 0 Double zinc ribbon DUF1013 PF06242.11 OAP63515.1 - 0.5 10.4 4.7 0.16 12.0 0.3 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1013) HypA PF01155.19 OAP63515.1 - 1.2 9.2 4.0 2.9 8.0 0.3 2.5 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF45 PF01863.17 OAP63515.1 - 1.9 8.5 4.8 0.38 10.8 0.9 1.9 2 0 0 2 2 2 0 Protein of unknown function DUF45 zf-Sec23_Sec24 PF04810.15 OAP63515.1 - 3.6 7.7 10.3 0.81 9.8 0.1 3.1 2 1 1 3 3 3 0 Sec23/Sec24 zinc finger DUF1776 PF08643.10 OAP63516.1 - 2.6e-57 194.5 0.0 3.3e-57 194.1 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Clr5 PF14420.6 OAP63517.1 - 7.4e-17 61.3 0.3 7.4e-17 61.3 0.3 2.1 3 0 0 3 3 3 1 Clr5 domain TPR_2 PF07719.17 OAP63517.1 - 0.052 13.7 0.5 0.25 11.6 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 OAP63517.1 - 0.11 13.4 1.8 91 4.3 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat FTA2 PF13095.6 OAP63518.1 - 2.2e-11 43.8 0.0 3.1e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 OAP63518.1 - 1.8e-05 24.2 0.0 2.2e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family WaaY PF06176.11 OAP63518.1 - 0.055 13.1 0.0 0.074 12.6 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) APH PF01636.23 OAP63518.1 - 0.084 12.8 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family zf-C2H2 PF00096.26 OAP63520.1 - 1e-09 38.3 11.6 2.2e-05 24.7 4.5 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OAP63520.1 - 2e-09 37.4 13.8 3.7e-05 23.9 0.4 3.6 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 OAP63520.1 - 9.6e-07 29.1 10.9 0.0013 19.4 3.2 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 OAP63520.1 - 5.9e-06 26.5 1.3 1.8e-05 25.0 1.3 1.9 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 OAP63520.1 - 9.3e-05 22.3 9.4 0.00012 22.0 2.4 2.8 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OAP63520.1 - 0.00074 19.7 1.8 0.00074 19.7 1.8 2.7 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding TEX13 PF15186.6 OAP63520.1 - 0.045 13.4 0.6 0.078 12.7 0.6 1.3 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family zf-C2H2_2 PF12756.7 OAP63520.1 - 0.065 13.6 1.3 0.065 13.6 1.3 2.2 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.6 OAP63520.1 - 0.11 12.5 4.2 2.9 7.9 0.4 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Actin_micro PF17003.5 OAP63520.1 - 0.16 11.1 0.3 0.23 10.6 0.3 1.1 1 0 0 1 1 1 0 Putative actin-like family zf-C2H2_11 PF16622.5 OAP63520.1 - 0.38 10.5 7.2 6.7 6.6 0.8 2.7 2 0 0 2 2 2 0 zinc-finger C2H2-type Sec1 PF00995.23 OAP63522.1 - 4.1e-114 382.9 0.0 5.1e-114 382.6 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Exo_endo_phos PF03372.23 OAP63523.1 - 9.5e-08 31.8 0.0 1.6e-07 31.1 0.0 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Zn_clus PF00172.18 OAP63524.1 - 9.2e-06 25.7 10.0 2e-05 24.6 10.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ThiF PF00899.21 OAP63525.1 - 3.2e-69 233.0 0.0 4.3e-69 232.6 0.0 1.1 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.10 OAP63525.1 - 6.7e-31 106.3 0.0 1.3e-30 105.3 0.0 1.5 1 0 0 1 1 1 1 E2 binding domain Shikimate_DH PF01488.20 OAP63525.1 - 0.00012 22.1 0.3 0.00034 20.7 0.0 1.8 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 OAP63525.1 - 0.043 14.1 0.2 0.66 10.2 0.1 2.6 3 0 0 3 3 3 0 Saccharopine dehydrogenase NADP binding domain Prolamin_like PF05617.11 OAP63525.1 - 0.072 13.3 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Prolamin-like Pyr_redox PF00070.27 OAP63525.1 - 0.089 13.4 0.0 0.19 12.3 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Ecm33 PF12454.8 OAP63525.1 - 0.13 12.4 2.3 0.26 11.5 2.3 1.4 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein NAD_binding_7 PF13241.6 OAP63525.1 - 0.14 12.6 0.0 0.3 11.5 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding UBA_e1_thiolCys PF10585.9 OAP63525.1 - 0.34 10.8 1.6 12 5.8 0.0 2.3 2 0 0 2 2 2 0 Ubiquitin-activating enzyme active site RNA_pol_A_bac PF01000.26 OAP63526.1 - 3.1e-24 85.5 0.0 6.8e-24 84.4 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 OAP63526.1 - 2.8e-20 71.5 0.0 5.2e-20 70.6 0.0 1.4 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Complex1_49kDa PF00346.19 OAP63527.1 - 7.3e-124 412.2 0.0 9.9e-124 411.8 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.19 OAP63527.1 - 0.0067 15.4 0.0 0.0097 14.8 0.0 1.2 1 0 0 1 1 1 1 Nickel-dependent hydrogenase Pkinase PF00069.25 OAP63528.1 - 1.7e-69 234.2 0.0 2.3e-69 233.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP63528.1 - 1.3e-36 126.2 0.0 2.1e-36 125.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAP63528.1 - 6.4e-06 25.7 0.0 8.7e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OAP63528.1 - 0.00061 19.2 0.0 0.0012 18.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 OAP63528.1 - 0.00099 18.8 1.3 1.3 8.6 0.0 3.0 2 1 1 3 3 3 2 Kinetochore Sim4 complex subunit FTA2 YrbL-PhoP_reg PF10707.9 OAP63528.1 - 0.036 13.6 0.0 0.14 11.6 0.0 2.1 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL adh_short_C2 PF13561.6 OAP63529.1 - 1.8e-54 184.8 0.2 1.1e-52 179.0 0.2 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP63529.1 - 2.2e-39 135.0 0.0 6.4e-38 130.2 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAP63529.1 - 6.8e-08 32.6 0.2 2e-07 31.1 0.2 1.8 1 1 0 1 1 1 1 KR domain 4HBT_2 PF13279.6 OAP63530.1 - 2.8e-27 95.6 0.0 4.1e-27 95.1 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 OAP63530.1 - 0.0014 18.9 0.0 0.0029 17.9 0.0 1.5 1 0 0 1 1 1 1 Thioesterase superfamily Pal1 PF08316.11 OAP63531.1 - 5.6e-07 30.4 2.7 6.6e-07 30.2 0.4 2.5 3 1 0 3 3 3 1 Pal1 cell morphology protein HVSL PF09749.9 OAP63532.1 - 1.1e-80 270.6 0.0 1.4e-80 270.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein CAP_N PF01213.19 OAP63532.1 - 0.57 9.6 2.8 0.91 8.9 2.8 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.11 OAP63532.1 - 2 8.4 4.5 0.91 9.6 2.2 1.6 2 0 0 2 2 2 0 Mitochondrial fission regulator Cgr1 PF03879.14 OAP63533.1 - 2.8e-31 108.1 29.1 3.4e-31 107.8 29.1 1.1 1 0 0 1 1 1 1 Cgr1 family DUF262 PF03235.14 OAP63533.1 - 1.1 9.4 5.5 1.1 9.3 5.5 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF262 VSG_B PF13206.6 OAP63533.1 - 2.7 7.2 11.0 3.1 7.0 11.0 1.0 1 0 0 1 1 1 0 Trypanosomal VSG domain DUF4192 PF13830.6 OAP63533.1 - 4.4 7.3 7.2 6.1 6.8 7.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) RR_TM4-6 PF06459.12 OAP63533.1 - 8.7 6.1 13.0 8.5 6.1 13.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Mito_carr PF00153.27 OAP63534.1 - 6.4e-60 199.1 1.0 2.1e-23 82.1 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein RRM_1 PF00076.22 OAP63536.1 - 2.6e-33 113.6 0.2 1.2e-18 66.7 0.1 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Telomere_reg-2 PF10193.9 OAP63536.1 - 2.7e-22 79.3 0.0 1.5e-21 76.9 0.0 2.3 2 0 0 2 2 2 1 Telomere length regulation protein Limkain-b1 PF11608.8 OAP63536.1 - 0.0006 19.8 0.1 0.33 11.1 0.0 2.9 2 0 0 2 2 2 2 Limkain b1 RcsD_ABL PF16359.5 OAP63536.1 - 0.095 12.9 0.0 0.3 11.2 0.0 1.8 2 0 0 2 2 2 0 RcsD-ABL domain p450 PF00067.22 OAP63537.1 - 8.1e-62 209.5 0.0 1e-61 209.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 TPR_1 PF00515.28 OAP63538.1 - 1.3e-23 81.8 1.3 2.4e-05 24.0 0.0 5.8 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 OAP63538.1 - 1.9e-21 74.4 5.2 0.00083 19.3 0.1 6.1 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_11 PF13414.6 OAP63538.1 - 1.9e-18 65.9 4.3 1.8e-06 27.5 0.0 5.0 4 1 1 5 5 5 3 TPR repeat TPR_14 PF13428.6 OAP63538.1 - 5.2e-17 61.1 3.4 0.00016 22.2 1.7 5.8 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 OAP63538.1 - 4.1e-15 56.2 9.3 3.1e-06 27.7 2.7 4.6 4 1 1 5 5 4 4 Tetratricopeptide repeat TPR_8 PF13181.6 OAP63538.1 - 1.1e-14 53.4 1.2 0.00036 20.5 0.0 5.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 OAP63538.1 - 2.1e-14 52.8 2.6 0.039 14.3 0.0 5.1 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_19 PF14559.6 OAP63538.1 - 9.2e-13 48.5 4.3 0.0073 16.8 0.4 4.5 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 OAP63538.1 - 4.4e-10 38.9 0.5 0.26 11.4 0.0 5.8 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_9 PF13371.6 OAP63538.1 - 1.3e-09 38.0 3.7 0.00013 22.0 1.6 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 OAP63538.1 - 2.7e-09 37.2 3.4 0.67 10.3 0.3 4.5 3 1 0 4 4 4 3 Tetratricopeptide repeat TPR_20 PF14561.6 OAP63538.1 - 6.6e-08 32.8 6.0 0.0028 17.9 0.2 4.3 4 1 1 5 5 5 3 Tetratricopeptide repeat ANAPC3 PF12895.7 OAP63538.1 - 2.3e-06 27.7 0.9 0.24 11.6 0.0 3.5 2 2 2 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 OAP63538.1 - 0.019 15.6 6.7 24 5.9 0.1 5.9 7 0 0 7 7 6 0 Tetratricopeptide repeat TOM20_plant PF06552.12 OAP63538.1 - 0.026 14.3 2.6 2.5 7.8 0.0 4.0 4 1 1 5 5 5 0 Plant specific mitochondrial import receptor subunit TOM20 NatB_MDM20 PF09797.9 OAP63538.1 - 0.028 13.4 0.1 0.041 12.8 0.1 1.2 1 0 0 1 1 1 0 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_15 PF13429.6 OAP63538.1 - 0.03 13.5 4.0 0.22 10.7 0.2 2.9 3 1 0 3 3 3 0 Tetratricopeptide repeat DUF1641 PF07849.11 OAP63538.1 - 0.13 12.2 0.2 0.24 11.3 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1641) DUF4192 PF13830.6 OAP63538.1 - 2.8 7.9 8.1 16 5.4 0.4 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4192) CorA PF01544.18 OAP63539.1 - 0.039 13.3 10.5 0.7 9.2 10.5 2.5 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein PX PF00787.24 OAP63540.1 - 1.5e-18 66.8 0.4 6.5e-18 64.8 0.1 2.1 2 0 0 2 2 2 1 PX domain Vps5 PF09325.10 OAP63540.1 - 1.3e-12 47.8 6.9 1.3e-06 28.2 0.2 2.1 1 1 1 2 2 2 2 Vps5 C terminal like BAR PF03114.18 OAP63540.1 - 0.0034 17.1 6.1 0.054 13.1 6.1 2.3 1 1 0 1 1 1 1 BAR domain CHAD PF05235.14 OAP63540.1 - 0.011 15.7 0.5 0.021 14.8 0.5 1.5 1 0 0 1 1 1 0 CHAD domain ADIP PF11559.8 OAP63540.1 - 0.014 15.4 4.3 0.4 10.7 0.1 3.0 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding DASH_Dad3 PF08656.10 OAP63540.1 - 0.019 15.0 0.1 0.13 12.3 0.0 2.4 2 1 0 2 2 2 0 DASH complex subunit Dad3 Sec34 PF04136.15 OAP63540.1 - 0.027 14.3 0.0 0.09 12.7 0.0 1.8 1 1 0 1 1 1 0 Sec34-like family Occludin_ELL PF07303.13 OAP63540.1 - 0.065 14.0 4.4 0.14 12.9 0.0 3.0 4 0 0 4 4 4 0 Occludin homology domain Spc7 PF08317.11 OAP63540.1 - 0.068 12.0 2.9 0.084 11.7 0.2 1.9 2 0 0 2 2 2 0 Spc7 kinetochore protein UPF0242 PF06785.11 OAP63540.1 - 1.2 9.2 4.9 8.7 6.4 0.3 2.3 1 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Dynamitin PF04912.14 OAP63541.1 - 4.2e-61 207.4 28.4 3e-59 201.3 28.4 2.8 1 1 0 1 1 1 1 Dynamitin FtsH_ext PF06480.15 OAP63541.1 - 0.0075 16.6 0.1 0.018 15.4 0.1 1.7 1 0 0 1 1 1 1 FtsH Extracellular Vfa1 PF08432.10 OAP63541.1 - 0.7 10.2 5.4 1.6 9.1 5.4 1.6 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Golgin_A5 PF09787.9 OAP63541.1 - 2.3 7.6 20.8 0.2 11.1 0.2 2.8 3 0 0 3 3 3 0 Golgin subfamily A member 5 HWE_HK PF07536.14 OAP63541.1 - 2.3 9.0 13.9 0.54 11.0 1.2 3.8 2 1 2 4 4 4 0 HWE histidine kinase DUF3619 PF12279.8 OAP63541.1 - 2.9 8.2 7.7 0.65 10.3 3.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3619) SWI-SNF_Ssr4 PF08549.10 OAP63541.1 - 4.5 5.8 14.7 0.26 9.9 7.1 1.9 1 1 0 2 2 2 0 Fungal domain of unknown function (DUF1750) APG6_N PF17675.1 OAP63541.1 - 6.1 7.4 26.9 2.6 8.6 15.3 3.5 3 1 0 3 3 3 0 Apg6 coiled-coil region Glyco_transf_22 PF03901.17 OAP63542.1 - 2.2e-34 119.4 20.3 2.8e-34 119.1 20.3 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Cupin_2 PF07883.11 OAP63543.1 - 2.4e-07 30.3 0.1 4.3e-07 29.6 0.1 1.4 1 0 0 1 1 1 1 Cupin domain CDO_I PF05995.12 OAP63543.1 - 0.016 14.6 0.0 0.39 10.0 0.0 2.1 1 1 0 1 1 1 0 Cysteine dioxygenase type I UCH PF00443.29 OAP63544.1 - 3e-56 190.8 0.4 7e-56 189.6 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OAP63544.1 - 2.2e-26 93.2 0.1 4.5e-19 69.2 0.0 2.6 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase YSIRK_signal PF04650.17 OAP63544.1 - 0.00037 20.3 1.0 0.00064 19.5 1.0 1.4 1 0 0 1 1 1 1 YSIRK type signal peptide Usp PF00582.26 OAP63544.1 - 0.46 11.0 3.2 1.2 9.6 3.2 1.7 1 0 0 1 1 1 0 Universal stress protein family DUF4407 PF14362.6 OAP63544.1 - 1 8.6 7.4 1.6 8.0 7.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) NusB PF01029.18 OAP63544.1 - 1.8 8.8 7.8 14 5.9 6.2 2.3 2 0 0 2 2 2 0 NusB family GBP_C PF02841.14 OAP63544.1 - 2.1 7.7 17.9 5.1 6.4 17.9 1.6 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain PA26 PF04636.13 OAP63544.1 - 2.9 6.7 7.6 4.6 6.0 7.6 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) EF-hand_6 PF13405.6 OAP63545.1 - 7e-15 53.6 0.4 2.8e-05 23.7 0.0 4.0 4 0 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.32 OAP63545.1 - 1.4e-12 46.2 2.5 2.1e-05 23.8 0.0 4.7 4 1 0 4 4 4 2 EF hand EF-hand_7 PF13499.6 OAP63545.1 - 1.2e-11 44.8 0.0 2.6e-07 31.0 1.6 2.9 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 OAP63545.1 - 6.8e-09 34.8 3.7 0.00017 21.0 0.1 3.5 3 1 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 OAP63545.1 - 1.5e-07 31.1 0.1 0.0019 18.0 0.0 3.1 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_14 PF17959.1 OAP63545.1 - 0.13 12.6 0.0 0.39 11.1 0.0 1.8 1 1 0 1 1 1 0 EF-hand domain ChaC PF04752.12 OAP63546.1 - 2.2e-45 154.9 0.1 9.3e-29 100.7 0.0 2.1 1 1 1 2 2 2 2 ChaC-like protein RRM_1 PF00076.22 OAP63547.1 - 4.7e-23 80.8 0.1 6.2e-23 80.4 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OAP63547.1 - 0.00047 20.2 0.0 0.00069 19.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif RRM_3 PF08777.11 OAP63547.1 - 0.1 12.7 0.1 0.14 12.2 0.1 1.2 1 0 0 1 1 1 0 RNA binding motif Abhydrolase_3 PF07859.13 OAP63549.1 - 0.0016 18.4 0.2 0.0065 16.3 0.1 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Lipase_3 PF01764.25 OAP63549.1 - 0.0084 16.0 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 OAP63549.1 - 0.013 14.8 0.0 0.029 13.6 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF915 PF06028.11 OAP63549.1 - 0.021 14.2 0.0 1.1 8.5 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) LIDHydrolase PF10230.9 OAP63549.1 - 0.045 13.3 0.0 9.2 5.7 0.0 2.2 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase Nnf1 PF03980.14 OAP63550.1 - 1.1e-28 99.8 6.0 1.1e-28 99.8 6.0 2.0 2 1 0 2 2 2 1 Nnf1 BAG6 PF12057.8 OAP63550.1 - 0.008 15.8 0.4 0.014 15.1 0.4 1.4 1 0 0 1 1 1 1 BCL2-associated athanogene 6 DUF4600 PF15372.6 OAP63550.1 - 0.011 16.2 7.4 1.2 9.6 3.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4600) BSP PF04450.12 OAP63550.1 - 0.06 13.1 0.0 3.6 7.3 0.0 2.2 1 1 0 2 2 2 0 Peptidase of plants and bacteria Exonuc_VII_L PF02601.15 OAP63550.1 - 0.22 11.0 2.9 0.29 10.7 2.9 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Syntaxin-6_N PF09177.11 OAP63550.1 - 0.38 11.3 4.8 0.25 11.9 2.0 2.1 1 1 0 2 2 2 0 Syntaxin 6, N-terminal CENP-F_leu_zip PF10473.9 OAP63550.1 - 0.51 10.4 12.6 0.061 13.4 8.5 1.6 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ADIP PF11559.8 OAP63550.1 - 0.55 10.3 7.3 0.94 9.5 7.3 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding HIP1_clath_bdg PF16515.5 OAP63550.1 - 0.94 10.1 10.2 4.2 8.1 10.2 2.1 1 1 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 FUSC PF04632.12 OAP63550.1 - 1.7 7.1 5.4 1.5 7.2 4.3 1.4 1 1 0 1 1 1 0 Fusaric acid resistance protein family Troponin PF00992.20 OAP63550.1 - 3 8.1 8.2 1 9.7 2.8 2.3 1 1 1 2 2 2 0 Troponin DUF1192 PF06698.11 OAP63550.1 - 3.2 7.9 7.3 7.8 6.6 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) CLZ PF16526.5 OAP63550.1 - 8.5 6.8 9.9 4.4 7.7 0.3 3.1 2 1 2 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF716 PF04819.12 OAP63551.1 - 9.9 5.8 8.4 0.96 9.1 3.1 1.9 1 1 1 2 2 2 0 Family of unknown function (DUF716) Phage_GP20 PF06810.11 OAP63552.1 - 0.24 11.2 5.7 0.044 13.6 1.1 1.9 2 0 0 2 2 2 0 Phage minor structural protein GP20 ALMT PF11744.8 OAP63552.1 - 2.6 6.8 8.7 0.068 12.0 2.0 1.8 2 0 0 2 2 2 0 Aluminium activated malate transporter MFS_1 PF07690.16 OAP63553.1 - 8.1e-21 74.3 21.3 8.1e-21 74.3 21.3 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF2062 PF09835.9 OAP63553.1 - 0.79 9.6 13.3 1.1 9.2 6.3 3.6 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2062) SIR2 PF02146.17 OAP63554.1 - 1e-31 110.3 0.0 1.8e-31 109.4 0.0 1.4 2 0 0 2 2 2 1 Sir2 family DUF202 PF02656.15 OAP63555.1 - 3.5e-09 37.0 0.4 6.1e-09 36.2 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF202) Cation_efflux PF01545.21 OAP63556.1 - 2.1e-53 181.0 7.5 2.2e-52 177.7 7.5 2.0 1 1 0 1 1 1 1 Cation efflux family Metallophos PF00149.28 OAP63557.1 - 6.2e-08 33.4 0.1 3.8e-06 27.5 0.0 2.3 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Ank_2 PF12796.7 OAP63558.1 - 3.7e-71 235.7 14.3 2.3e-17 63.4 0.0 7.8 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAP63558.1 - 3.7e-58 193.2 13.8 1.2e-11 44.9 0.0 9.2 5 3 6 11 11 11 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 OAP63558.1 - 1e-48 162.8 22.3 6.8e-09 35.8 0.2 11.5 2 2 11 13 13 13 12 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAP63558.1 - 5.8e-48 155.3 11.7 0.0044 17.4 0.1 13.5 14 0 0 14 14 13 11 Ankyrin repeat Ank PF00023.30 OAP63558.1 - 1.3e-46 155.1 20.6 0.00036 20.9 0.0 12.5 12 0 0 12 12 12 10 Ankyrin repeat Helo_like_N PF17111.5 OAP63558.1 - 4e-11 42.7 0.4 9.9e-11 41.4 0.4 1.7 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins NACHT PF05729.12 OAP63558.1 - 6.5e-08 32.7 0.0 1.8e-07 31.2 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 OAP63558.1 - 2.8e-05 24.6 2.2 0.00013 22.4 0.0 3.1 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 OAP63558.1 - 0.00076 19.8 0.0 0.0034 17.6 0.0 2.1 1 0 0 1 1 1 1 AAA domain DUF1949 PF09186.11 OAP63558.1 - 0.042 13.7 0.5 16 5.5 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1949) Mg_chelatase PF01078.21 OAP63558.1 - 0.1 12.0 0.0 0.28 10.6 0.0 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF5559 PF17714.1 OAP63558.1 - 0.16 11.9 0.6 0.44 10.4 0.6 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5559) CAP_N PF01213.19 OAP63558.1 - 0.23 10.9 0.6 0.58 9.6 0.6 1.6 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Tyrosinase PF00264.20 OAP63560.1 - 1.4e-47 162.8 5.2 1.4e-47 162.8 5.2 2.9 2 1 1 3 3 3 1 Common central domain of tyrosinase Tyosinase_C PF18132.1 OAP63560.1 - 6.2e-14 52.7 0.0 1.5e-13 51.5 0.0 1.7 1 0 0 1 1 1 1 Tyosinase C-terminal domain GPI-anchored PF10342.9 OAP63560.1 - 6.2e-13 49.3 2.9 9e-13 48.8 0.1 2.7 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family SHE3 PF17078.5 OAP63560.1 - 1.9e-05 24.5 25.6 0.00013 21.8 25.6 2.0 1 1 0 1 1 1 1 SWI5-dependent HO expression protein 3 ADIP PF11559.8 OAP63560.1 - 0.00013 22.1 31.5 0.015 15.4 8.5 2.5 2 0 0 2 2 2 2 Afadin- and alpha -actinin-Binding Matrilin_ccoil PF10393.9 OAP63560.1 - 0.03 14.2 1.9 0.17 11.8 0.1 2.7 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin CENP-F_leu_zip PF10473.9 OAP63560.1 - 0.079 13.0 24.4 0.21 11.6 12.0 2.3 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 RasGAP_C PF03836.15 OAP63560.1 - 0.4 10.8 17.4 2.8 8.1 2.3 2.4 2 0 0 2 2 2 0 RasGAP C-terminus Baculo_PEP_C PF04513.12 OAP63560.1 - 0.9 9.6 8.7 0.052 13.6 1.6 2.4 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus YabA PF06156.13 OAP63560.1 - 3.8 8.2 17.3 0.26 11.9 6.5 2.6 2 0 0 2 2 2 0 Initiation control protein YabA DUF641 PF04859.12 OAP63560.1 - 4 7.8 22.6 3.1 8.1 4.1 2.5 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) Macoilin PF09726.9 OAP63560.1 - 8.9 4.7 34.1 0.0088 14.7 18.0 2.2 1 1 1 2 2 2 0 Macoilin family PGA2 PF07543.12 OAP63561.1 - 5.5e-17 62.0 0.5 1.2e-16 61.0 0.5 1.4 1 1 0 1 1 1 1 Protein trafficking PGA2 Crl PF07417.12 OAP63561.1 - 4.1e-06 26.9 0.3 6.7e-06 26.2 0.1 1.4 2 0 0 2 2 2 1 Sigma factor-binding transcriptional regulator Crl PCC_BT PF18140.1 OAP63562.1 - 0.018 15.3 0.0 0.037 14.4 0.0 1.6 1 1 1 2 2 2 0 Propionyl-coenzyme A carboxylase BT domain Arylsulfotran_2 PF14269.6 OAP63563.1 - 1.8e-58 198.3 4.1 2.6e-58 197.8 4.1 1.3 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 OAP63563.1 - 1.9e-20 73.1 6.2 6.4e-20 71.4 6.2 1.6 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Aminopep PF10023.9 OAP63563.1 - 0.058 12.7 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Putative aminopeptidase STT3 PF02516.14 OAP63564.1 - 9.7e-144 479.9 36.6 8.8e-139 463.6 34.2 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit RNase_T PF00929.24 OAP63565.1 - 4.5e-08 33.8 0.0 2.7e-07 31.3 0.0 2.1 1 1 0 1 1 1 1 Exonuclease RRM_1 PF00076.22 OAP63566.1 - 2.1e-13 49.9 0.6 1.3e-11 44.1 0.0 2.8 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OAP63566.1 - 0.037 14.1 0.0 0.33 11.1 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif Sds3 PF08598.11 OAP63567.1 - 6.6e-19 68.8 0.1 6.6e-19 68.8 0.1 3.0 2 1 0 2 2 2 1 Sds3-like MFS_1 PF07690.16 OAP63568.1 - 2e-29 102.6 16.8 2e-29 102.6 16.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Gly-zipper_Omp PF13488.6 OAP63568.1 - 0.11 12.6 1.0 0.51 10.4 0.1 2.6 2 0 0 2 2 2 0 Glycine zipper DUF21 PF01595.20 OAP63568.1 - 0.33 10.7 2.8 5 6.8 0.2 2.5 2 0 0 2 2 2 0 Cyclin M transmembrane N-terminal domain Amino_oxidase PF01593.24 OAP63569.1 - 1.1e-60 206.2 0.0 3.1e-60 204.8 0.0 1.6 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OAP63569.1 - 1.8e-13 50.5 0.3 3.9e-13 49.4 0.3 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAP63569.1 - 6.4e-07 29.3 0.0 1e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 OAP63569.1 - 1.4e-06 27.8 0.3 2.2e-06 27.1 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 OAP63569.1 - 2.3e-06 27.1 0.2 1.6e-05 24.3 0.2 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 OAP63569.1 - 8.2e-06 25.3 1.7 1.5e-05 24.4 1.7 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 OAP63569.1 - 9.5e-06 24.9 1.3 1.8e-05 24.0 1.3 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 OAP63569.1 - 0.00041 20.9 0.9 0.0021 18.6 0.8 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAP63569.1 - 0.00045 19.0 0.2 0.00079 18.2 0.2 1.3 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.22 OAP63569.1 - 0.00049 19.3 0.9 0.00068 18.8 0.2 1.5 2 0 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.17 OAP63569.1 - 0.00049 19.4 0.2 0.00094 18.5 0.2 1.4 1 0 0 1 1 1 1 Thi4 family K_oxygenase PF13434.6 OAP63569.1 - 0.00094 18.4 0.1 0.017 14.3 0.0 2.4 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.12 OAP63569.1 - 0.0081 15.3 0.1 0.012 14.7 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_oxidored PF12831.7 OAP63569.1 - 0.015 14.7 0.5 0.022 14.1 0.5 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 OAP63569.1 - 0.026 13.8 0.1 0.042 13.1 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 OAP63569.1 - 0.035 14.0 0.1 0.06 13.2 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 OAP63569.1 - 0.21 11.9 0.5 0.52 10.6 0.5 1.7 1 0 0 1 1 1 0 TrkA-N domain adh_short PF00106.25 OAP63571.1 - 2.1e-36 125.2 0.0 3e-36 124.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP63571.1 - 5.7e-28 98.1 0.0 7.6e-28 97.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Sacchrp_dh_NADP PF03435.18 OAP63571.1 - 2.6e-05 24.5 0.1 7.7e-05 23.0 0.1 1.7 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain KR PF08659.10 OAP63571.1 - 4.5e-05 23.4 0.0 7.9e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAP63571.1 - 0.00054 19.5 0.0 0.001 18.6 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 OAP63571.1 - 0.0021 17.7 0.3 0.0041 16.7 0.3 1.4 1 0 0 1 1 1 1 NmrA-like family 3HCDH_N PF02737.18 OAP63571.1 - 0.0093 15.9 0.1 0.014 15.3 0.1 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 OAP63571.1 - 0.021 14.9 0.0 0.033 14.2 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Haem_degrading PF03928.14 OAP63572.1 - 2.5e-29 101.7 0.4 3e-29 101.5 0.4 1.1 1 0 0 1 1 1 1 Haem-degrading MFS_1 PF07690.16 OAP63574.1 - 4.2e-20 72.0 28.3 6.4e-11 41.8 7.1 3.2 3 0 0 3 3 3 3 Major Facilitator Superfamily LacY_symp PF01306.19 OAP63574.1 - 0.0012 17.7 4.4 0.0077 15.0 0.5 2.9 3 0 0 3 3 3 2 LacY proton/sugar symporter AKAP2_C PF15304.6 OAP63575.1 - 0.99 8.6 4.7 0.18 11.1 0.6 1.8 2 1 0 2 2 2 0 A-kinase anchor protein 2 C-terminus Pkinase PF00069.25 OAP63577.1 - 5.5e-05 22.7 0.0 8.5e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 OAP63577.1 - 0.002 17.5 0.0 0.0034 16.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family SWIRM-assoc_2 PF16496.5 OAP63577.1 - 8 5.2 7.7 12 4.6 7.7 1.2 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal PAS_9 PF13426.7 OAP63578.1 - 4.1e-15 55.9 0.0 1.5e-13 50.9 0.0 2.5 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 OAP63578.1 - 0.021 14.8 0.0 0.22 11.5 0.0 2.3 2 0 0 2 2 2 0 PAS fold HET PF06985.11 OAP63579.1 - 2.1e-25 89.8 0.0 3.3e-25 89.2 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Rop-like PF05082.13 OAP63579.1 - 0.099 12.5 0.0 0.31 10.9 0.0 1.7 2 0 0 2 2 2 0 Rop-like Coiled-coil_56 PF09813.9 OAP63580.1 - 9.4e-05 22.4 0.0 0.00012 22.1 0.0 1.2 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 Cyclase PF04199.13 OAP63581.1 - 4.1e-11 43.3 0.0 8.2e-11 42.3 0.0 1.4 1 1 0 1 1 1 1 Putative cyclase Tannase PF07519.11 OAP63582.1 - 1.3e-99 334.3 3.3 1.5e-99 334.0 3.3 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase p450 PF00067.22 OAP63583.1 - 5.8e-31 107.7 0.0 1.1e-30 106.8 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 PilX_N PF14341.6 OAP63583.1 - 0.1 12.5 1.4 0.3 11.1 1.2 1.9 2 0 0 2 2 2 0 PilX N-terminal DUF3431 PF11913.8 OAP63584.1 - 2.1e-89 299.0 0.2 2.6e-89 298.7 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) zf-rbx1 PF12678.7 OAP63585.1 - 6.3e-11 42.4 2.9 1.4e-10 41.3 2.9 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 OAP63585.1 - 2.2e-08 34.3 6.3 4.4e-08 33.3 2.9 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 OAP63585.1 - 2.1e-06 27.5 2.8 3.7e-06 26.7 2.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OAP63585.1 - 2.9e-05 23.8 3.5 2.9e-05 23.8 3.5 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAP63585.1 - 3.1e-05 23.9 3.3 6.7e-05 22.8 3.3 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Zn_ribbon_17 PF17120.5 OAP63585.1 - 7.1e-05 22.4 0.5 0.00014 21.4 0.5 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 OAP63585.1 - 0.0005 20.1 2.7 0.0018 18.3 2.7 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 OAP63585.1 - 0.0007 19.4 5.3 0.0018 18.1 1.7 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAP63585.1 - 0.0017 18.3 4.1 0.011 15.7 4.7 1.9 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_11 PF17123.5 OAP63585.1 - 0.016 14.9 1.3 0.37 10.6 0.2 2.5 2 0 0 2 2 2 0 RING-like zinc finger zf-C3HC4_4 PF15227.6 OAP63585.1 - 0.062 13.5 1.3 0.12 12.5 1.3 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 OAP63585.1 - 0.067 13.1 4.3 0.16 11.9 4.3 1.6 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zinc_ribbon_16 PF17034.5 OAP63585.1 - 0.068 13.4 0.2 0.18 12.0 0.2 1.7 1 0 0 1 1 1 0 Zinc-ribbon like family RCR PF12273.8 OAP63586.1 - 2.4e-13 50.8 7.6 4e-13 50.1 7.6 1.5 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red tRNA-synt_2c PF01411.19 OAP63588.1 - 3.3e-219 729.0 0.0 4.7e-219 728.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 OAP63588.1 - 1.9e-17 63.1 1.3 4.2e-17 62.0 1.3 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 OAP63588.1 - 5.7e-13 49.5 0.4 1.8e-12 47.8 0.4 2.0 1 0 0 1 1 1 1 DHHA1 domain PolyA_pol_arg_C PF12626.7 OAP63588.1 - 0.066 13.3 0.5 0.14 12.2 0.5 1.5 1 0 0 1 1 1 0 Polymerase A arginine-rich C-terminus GFA PF04828.14 OAP63589.1 - 6.3e-19 68.1 0.0 8.5e-19 67.7 0.0 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme RBM1CTR PF08081.11 OAP63589.1 - 0.061 13.4 0.9 0.2 11.7 0.2 1.9 2 0 0 2 2 2 0 RBM1CTR (NUC064) family adh_short PF00106.25 OAP63591.1 - 2.8e-27 95.5 0.2 3.3e-20 72.4 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAP63591.1 - 6.3e-21 75.0 1.0 3.1e-18 66.2 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP63591.1 - 0.00011 22.2 0.0 0.00032 20.7 0.0 1.7 2 0 0 2 2 2 1 KR domain Asp_Glu_race PF01177.22 OAP63592.1 - 4.5e-10 39.7 0.0 7.1e-10 39.1 0.0 1.4 1 1 0 1 1 1 1 Asp/Glu/Hydantoin racemase AroM PF07302.11 OAP63592.1 - 0.0085 15.5 0.1 0.015 14.7 0.1 1.3 1 0 0 1 1 1 1 AroM protein Amdase PF17645.1 OAP63592.1 - 0.037 13.6 0.3 0.35 10.5 0.0 2.2 2 1 1 3 3 3 0 Arylmalonate decarboxylase CN_hydrolase PF00795.22 OAP63593.1 - 1.4e-35 123.0 0.0 1.7e-35 122.7 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Amidohydro_1 PF01979.20 OAP63594.1 - 4.4e-26 92.0 0.0 8.5e-26 91.1 0.0 1.5 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 OAP63594.1 - 4e-20 72.7 0.0 1.2e-08 34.9 0.0 2.7 3 0 0 3 3 3 2 Amidohydrolase family Urease_alpha PF00449.20 OAP63594.1 - 0.0013 19.1 0.6 0.0026 18.1 0.6 1.5 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain YdjC PF04794.12 OAP63594.1 - 0.064 13.2 0.1 0.12 12.4 0.1 1.5 1 0 0 1 1 1 0 YdjC-like protein Amidohydro_1 PF01979.20 OAP63595.1 - 2.1e-26 93.1 0.3 1.1e-12 48.0 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 OAP63595.1 - 7.5e-16 58.6 0.1 1.4e-07 31.4 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family RPN7 PF10602.9 OAP63596.1 - 1.2e-53 181.4 0.4 2e-53 180.7 0.4 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 OAP63596.1 - 1.3e-09 38.5 0.0 4.3e-09 36.8 0.0 2.0 1 0 0 1 1 1 1 PCI domain DUF2225 PF09986.9 OAP63596.1 - 0.094 12.4 0.3 0.15 11.7 0.3 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-C2H2 PF00096.26 OAP63597.1 - 0.00022 21.5 19.2 0.7 10.5 1.1 5.1 5 0 0 5 5 4 4 Zinc finger, C2H2 type zf-met PF12874.7 OAP63597.1 - 0.033 14.6 1.5 2 8.9 0.6 3.0 2 0 0 2 2 2 0 Zinc-finger of C2H2 type CNDH2_C PF16858.5 OAP63597.1 - 0.061 13.2 3.0 0.098 12.5 3.0 1.3 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term zf-C2H2_6 PF13912.6 OAP63597.1 - 0.083 12.9 1.5 4.7 7.3 0.4 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger DUF4611 PF15387.6 OAP63597.1 - 0.094 13.0 8.3 0.19 11.9 8.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) TT_ORF2 PF02957.15 OAP63597.1 - 0.094 13.6 4.8 0.14 13.1 2.8 2.2 1 1 1 2 2 2 0 TT viral ORF2 CDC45 PF02724.14 OAP63597.1 - 0.11 10.7 2.8 0.15 10.3 2.8 1.1 1 0 0 1 1 1 0 CDC45-like protein zf-C2H2_4 PF13894.6 OAP63597.1 - 0.14 13.0 20.0 0.49 11.4 0.6 5.2 5 1 0 5 5 4 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OAP63597.1 - 0.27 11.6 7.0 3.3 8.1 0.8 3.6 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Nop14 PF04147.12 OAP63597.1 - 0.56 8.4 6.4 0.77 7.9 6.4 1.1 1 0 0 1 1 1 0 Nop14-like family Cwf_Cwc_15 PF04889.12 OAP63597.1 - 0.82 9.4 11.8 2.5 7.8 10.0 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein zf-C2H2_2 PF12756.7 OAP63597.1 - 1 9.7 4.3 0.34 11.3 0.3 2.3 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) PBP1_TM PF14812.6 OAP63597.1 - 1.1 9.7 8.9 3.3 8.2 8.9 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FOXP-CC PF16159.5 OAP63597.1 - 1.4 9.6 4.8 19 5.9 0.6 3.3 3 0 0 3 3 3 0 FOXP coiled-coil domain FAM176 PF14851.6 OAP63597.1 - 2.9 7.6 5.4 5.3 6.7 5.4 1.4 1 0 0 1 1 1 0 FAM176 family ATP_transf PF09830.9 OAP63598.1 - 1.5e-22 79.5 0.0 2.4e-22 78.9 0.0 1.4 1 0 0 1 1 1 1 ATP adenylyltransferase DUF4931 PF16285.5 OAP63598.1 - 0.0045 16.3 0.0 0.0071 15.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4931) Tetradecapep PF08187.11 OAP63599.1 - 0.096 12.8 0.7 21 5.4 0.1 2.7 2 0 0 2 2 2 0 Myoactive tetradecapeptides family Sugar_tr PF00083.24 OAP63600.1 - 6.4e-72 242.8 23.9 7.5e-72 242.6 23.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP63600.1 - 8.1e-20 71.0 30.2 8.1e-20 71.0 30.2 2.0 1 1 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.6 OAP63600.1 - 5.4e-05 21.9 4.2 5.4e-05 21.9 4.2 2.4 2 0 0 2 2 2 1 MFS/sugar transport protein T3SS_LEE_assoc PF13327.6 OAP63600.1 - 0.065 13.2 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Type III secretion system subunit EMP70 PF02990.16 OAP63600.1 - 2 7.0 13.6 0.95 8.0 1.3 2.3 2 0 0 2 2 2 0 Endomembrane protein 70 SNF2_N PF00176.23 OAP63602.1 - 8.2e-52 176.1 0.2 2.5e-51 174.5 0.0 1.8 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OAP63602.1 - 2.2e-19 69.8 0.1 4e-18 65.8 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAP63602.1 - 5.3e-08 33.0 0.0 1.4e-07 31.7 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HHH_3 PF12836.7 OAP63602.1 - 0.00033 20.8 0.0 0.00094 19.4 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif ERCC3_RAD25_C PF16203.5 OAP63602.1 - 0.011 15.0 0.1 0.022 14.0 0.1 1.4 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Ank_2 PF12796.7 OAP63603.1 - 2.8e-20 72.7 0.0 2e-08 34.7 0.0 3.3 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAP63603.1 - 1.4e-17 63.8 0.1 8.3e-07 29.4 0.0 5.3 3 2 2 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAP63603.1 - 5.7e-17 60.1 0.3 0.0037 17.7 0.0 7.1 6 2 1 7 7 7 4 Ankyrin repeat Ank PF00023.30 OAP63603.1 - 2.4e-16 59.4 1.6 4.2e-05 23.8 0.1 6.2 5 2 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 OAP63603.1 - 1.6e-10 41.0 0.9 0.00047 20.4 0.0 5.2 3 2 2 5 5 5 2 Ankyrin repeats (many copies) DUF2795 PF11387.8 OAP63603.1 - 0.14 12.3 0.2 1.4 9.2 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2795) VMA21 PF09446.10 OAP63604.1 - 7.6e-15 54.8 11.1 1.1e-14 54.3 11.1 1.2 1 0 0 1 1 1 1 VMA21-like domain DUF2406 PF10295.9 OAP63605.1 - 2.4e-21 76.2 2.5 2.5e-21 76.1 0.9 2.0 2 0 0 2 2 2 1 Uncharacterised protein (DUF2406) G6PD_C PF02781.16 OAP63606.1 - 1.3e-115 385.6 0.0 2.1e-115 384.9 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 OAP63606.1 - 1.3e-60 205.0 0.0 2.3e-60 204.2 0.0 1.4 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Ribosomal_L35Ae PF01247.18 OAP63607.1 - 1.2e-45 153.6 0.2 1.3e-45 153.5 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 OAP63607.1 - 7e-05 23.0 0.0 0.036 14.3 0.0 2.1 2 0 0 2 2 2 2 RimM N-terminal domain DUF2080 PF09853.9 OAP63607.1 - 0.2 11.4 1.5 1.1 9.0 0.1 2.3 2 1 0 2 2 2 0 Putative transposon-encoded protein (DUF2080) MFS_2 PF13347.6 OAP63609.1 - 1.9e-06 26.7 5.2 2.2e-06 26.5 4.0 1.8 2 0 0 2 2 2 1 MFS/sugar transport protein YjcB PF15940.5 OAP63609.1 - 0.071 13.3 0.7 0.42 10.8 0.3 2.4 2 0 0 2 2 2 0 Family of unknown function Pyrophosphatase PF00719.19 OAP63610.1 - 6e-58 195.2 0.1 7.5e-58 194.9 0.1 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase Dus PF01207.17 OAP63611.1 - 3.1e-44 151.3 0.0 3.1e-44 151.3 0.0 2.0 1 1 0 2 2 2 1 Dihydrouridine synthase (Dus) DUF4770 PF15994.5 OAP63611.1 - 0.28 11.4 7.3 0.49 10.6 7.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) Sec20 PF03908.13 OAP63612.1 - 7.5e-11 41.8 0.1 7.5e-11 41.8 0.1 2.8 3 1 1 4 4 4 1 Sec20 AAA PF00004.29 OAP63613.1 - 2.3e-11 44.2 0.0 4.7e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 OAP63613.1 - 4.2e-11 43.1 0.0 1e-10 41.9 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 OAP63613.1 - 4.4e-09 36.3 0.0 5.9e-08 32.6 0.0 2.4 2 1 0 2 2 2 1 DNA polymerase III, delta subunit Rad17 PF03215.15 OAP63613.1 - 3.3e-05 23.9 0.0 5e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain RuvB_N PF05496.12 OAP63613.1 - 5.8e-05 22.9 0.0 0.00025 20.8 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 OAP63613.1 - 0.00027 20.4 0.0 0.0044 16.4 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 OAP63613.1 - 0.00034 20.9 0.1 0.0031 17.8 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 OAP63613.1 - 0.00034 20.5 0.3 0.0016 18.3 0.3 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OAP63613.1 - 0.00057 20.3 0.3 0.004 17.5 0.2 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 OAP63613.1 - 0.00081 19.8 0.0 0.0022 18.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_assoc_2 PF16193.5 OAP63613.1 - 0.0012 19.2 0.8 0.0027 18.0 0.1 2.0 2 0 0 2 2 1 1 AAA C-terminal domain AAA_24 PF13479.6 OAP63613.1 - 0.0053 16.5 0.0 0.013 15.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 OAP63613.1 - 0.012 15.6 0.0 1.2 9.1 0.0 2.6 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit DUF815 PF05673.13 OAP63613.1 - 0.018 14.2 0.0 0.033 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) SPAN-X PF07458.12 OAP63613.1 - 0.037 14.5 2.4 0.059 13.8 1.3 1.9 2 0 0 2 2 2 0 Sperm protein associated with nucleus, mapped to X chromosome RNA_helicase PF00910.22 OAP63613.1 - 0.049 14.0 0.1 0.23 11.9 0.0 2.2 2 1 0 2 2 1 0 RNA helicase DUF2075 PF09848.9 OAP63613.1 - 0.066 12.5 0.0 0.18 11.0 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Ax_dynein_light PF10211.9 OAP63614.1 - 0.38 10.7 10.5 0.079 12.9 5.6 2.1 2 0 0 2 2 2 0 Axonemal dynein light chain APG6_N PF17675.1 OAP63614.1 - 1.4 9.5 7.1 4.6 7.8 7.1 1.9 1 0 0 1 1 1 0 Apg6 coiled-coil region HSP70 PF00012.20 OAP63615.1 - 2.8e-09 35.7 0.1 1e-06 27.3 0.0 2.2 2 0 0 2 2 2 2 Hsp70 protein DUF3431 PF11913.8 OAP63616.1 - 1.2e-83 280.1 0.3 1.7e-83 279.7 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) DUF1746 PF08508.10 OAP63617.1 - 7.5e-18 64.9 5.6 1.1e-17 64.4 5.6 1.3 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1746) CLP_protease PF00574.23 OAP63618.1 - 5.3e-68 228.5 0.1 6.9e-68 228.1 0.1 1.1 1 0 0 1 1 1 1 Clp protease TPR_2 PF07719.17 OAP63619.1 - 6.5e-05 22.7 2.1 0.0043 17.1 0.2 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat Clr5 PF14420.6 OAP63619.1 - 0.0012 19.0 0.8 0.0034 17.6 0.8 1.8 1 0 0 1 1 1 1 Clr5 domain TPR_14 PF13428.6 OAP63619.1 - 0.0016 19.1 1.2 2.4 9.2 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 OAP63619.1 - 0.0033 17.7 1.3 0.014 15.7 0.4 2.6 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_MalT PF17874.1 OAP63619.1 - 0.0047 16.3 1.0 0.046 13.1 1.2 2.2 1 1 1 2 2 2 1 MalT-like TPR region TPR_1 PF00515.28 OAP63619.1 - 0.014 15.2 0.8 0.58 10.1 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 OAP63619.1 - 0.032 14.7 3.5 0.09 13.3 0.3 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 OAP63619.1 - 0.47 10.2 2.2 2.3 8.0 0.1 2.9 3 0 0 3 3 3 0 TPR repeat TPR_6 PF13174.6 OAP63619.1 - 7.3 7.5 6.5 13 6.7 0.2 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF1152 PF06626.12 OAP63620.1 - 0.00044 19.5 1.1 0.28 10.3 0.1 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1152) dCMP_cyt_deam_1 PF00383.23 OAP63621.1 - 2.1e-12 46.8 0.1 3.3e-12 46.2 0.1 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 OAP63621.1 - 4.3e-07 30.2 0.2 0.00017 21.8 0.1 2.1 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 OAP63621.1 - 0.0012 18.4 0.9 0.18 11.4 0.2 2.1 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases COesterase PF00135.28 OAP63622.1 - 3.4e-26 92.2 0.2 2.6e-25 89.3 0.1 1.8 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 OAP63622.1 - 0.00064 19.6 0.3 0.003 17.5 0.3 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Acetyltransf_1 PF00583.25 OAP63623.1 - 2.9e-13 50.1 0.0 4.2e-13 49.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OAP63623.1 - 1e-11 44.9 0.0 1.8e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OAP63623.1 - 1.7e-09 38.0 0.0 2.4e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAP63623.1 - 8.7e-09 35.2 0.0 1.2e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 OAP63623.1 - 0.0021 18.1 0.0 0.0033 17.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 OAP63623.1 - 0.014 15.6 0.3 0.057 13.6 0.3 2.0 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain But2 PF09792.9 OAP63625.1 - 1.2e-40 139.2 3.3 1.4e-40 139.0 3.3 1.1 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain DUF1599 PF07659.11 OAP63626.1 - 0.59 10.6 3.2 95 3.6 0.0 3.4 4 0 0 4 4 4 0 Nucleotide modification associated domain 1 DNAP_B_exo_N PF08452.10 OAP63626.1 - 1.2 8.7 4.7 10 5.7 0.1 2.7 3 0 0 3 3 3 0 DNA polymerase family B exonuclease domain, N-terminal Myb_DNA-bind_3 PF12776.7 OAP63627.1 - 0.22 12.5 1.2 0.4 11.7 0.2 1.9 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain MARVEL PF01284.23 OAP63629.1 - 3.7e-07 30.3 13.0 4.9e-07 29.9 13.0 1.2 1 0 0 1 1 1 1 Membrane-associating domain HLH PF00010.26 OAP63630.1 - 1.8e-08 34.2 0.0 4.1e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PspB PF06667.12 OAP63630.1 - 0.12 12.4 1.2 0.14 12.2 0.1 1.7 2 0 0 2 2 2 0 Phage shock protein B Flavodoxin_5 PF12724.7 OAP63632.1 - 1.7e-25 89.9 0.0 2.1e-25 89.6 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin domain Flavodoxin_1 PF00258.25 OAP63632.1 - 1.2e-05 25.6 0.0 1.4e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_3 PF12641.7 OAP63632.1 - 0.009 15.7 0.0 0.012 15.3 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin domain RNase_H_2 PF13482.6 OAP63632.1 - 0.033 14.2 0.0 0.052 13.5 0.0 1.3 1 0 0 1 1 1 0 RNase_H superfamily PaRep2b PF07775.11 OAP63632.1 - 0.13 10.7 0.0 0.17 10.3 0.0 1.1 1 0 0 1 1 1 0 PaRep2b protein Zn_clus PF00172.18 OAP63633.1 - 3.1e-07 30.4 15.3 5.4e-07 29.6 15.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tim17 PF02466.19 OAP63634.1 - 9.3e-15 55.0 0.6 1.5e-14 54.3 0.6 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF5518 PF17647.1 OAP63634.1 - 0.53 10.4 3.9 18 5.5 1.5 2.3 1 1 1 2 2 2 0 Family of unknown function (DUF5518) Brix PF04427.18 OAP63635.1 - 9.4e-29 100.9 0.0 1.3e-28 100.5 0.0 1.2 1 0 0 1 1 1 1 Brix domain TFIIA PF03153.13 OAP63635.1 - 0.51 10.3 7.7 0.7 9.8 7.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Transferase PF02458.15 OAP63636.1 - 5.1e-22 78.1 0.0 3e-20 72.3 0.0 2.0 2 0 0 2 2 2 2 Transferase family Sulfotransfer_4 PF17784.1 OAP63637.1 - 3.5e-72 242.7 0.1 4.4e-72 242.4 0.1 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OAP63637.1 - 1.2e-06 29.1 0.1 0.00066 20.1 0.1 2.6 2 1 1 3 3 3 2 Sulfotransferase family Arylsulfotran_2 PF14269.6 OAP63638.1 - 3.8e-57 193.9 3.1 5.7e-57 193.4 3.1 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 OAP63638.1 - 2.8e-15 56.1 2.4 4.2e-14 52.2 2.4 2.2 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Tic22 PF04278.12 OAP63638.1 - 0.042 13.2 0.1 3.4 7.0 0.0 2.2 2 0 0 2 2 2 0 Tic22-like family ATG22 PF11700.8 OAP63638.1 - 0.1 11.2 0.0 0.16 10.5 0.0 1.2 1 0 0 1 1 1 0 Vacuole effluxer Atg22 like Spore_III_AB PF09548.10 OAP63638.1 - 0.16 12.1 0.0 0.25 11.5 0.0 1.2 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) MFS_1 PF07690.16 OAP63639.1 - 8.3e-16 57.9 46.4 8.8e-16 57.8 12.6 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily zf-C2H2 PF00096.26 OAP63640.1 - 3.3e-24 83.9 60.1 0.00011 22.5 0.6 10.0 10 0 0 10 10 10 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAP63640.1 - 1e-21 75.7 51.4 0.00051 20.7 0.3 9.9 10 0 0 10 10 9 7 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OAP63640.1 - 7.3e-11 42.0 57.4 2.1e-05 24.8 2.8 10.0 10 0 0 10 10 10 5 Zinc-finger double domain zf-C2H2_11 PF16622.5 OAP63640.1 - 1.5e-06 27.9 10.0 0.86 9.4 0.2 6.2 6 0 0 6 6 6 3 zinc-finger C2H2-type zf-C2H2_aberr PF17017.5 OAP63640.1 - 2e-06 28.0 19.4 0.35 11.0 3.3 5.2 3 2 1 5 5 5 4 Aberrant zinc-finger zf-H2C2_5 PF13909.6 OAP63640.1 - 1.8e-05 24.4 37.8 0.44 10.3 0.1 8.8 8 0 0 8 8 8 4 C2H2-type zinc-finger domain zf-C2H2_3rep PF18868.1 OAP63640.1 - 0.00012 22.8 20.8 0.011 16.4 3.7 5.1 1 1 4 5 5 5 3 Zinc finger C2H2-type, 3 repeats FOXP-CC PF16159.5 OAP63640.1 - 0.00019 22.0 34.3 0.48 11.1 0.3 8.3 5 2 4 9 9 9 2 FOXP coiled-coil domain zf-Di19 PF05605.12 OAP63640.1 - 0.00051 20.3 43.1 0.034 14.4 3.1 7.4 4 3 2 7 7 7 4 Drought induced 19 protein (Di19), zinc-binding GAGA PF09237.11 OAP63640.1 - 0.0087 15.8 11.1 0.03 14.1 0.3 4.3 5 0 0 5 5 5 1 GAGA factor zf-C2H2_8 PF15909.5 OAP63640.1 - 0.0099 16.2 23.5 0.02 15.2 0.4 4.4 4 1 1 5 5 5 2 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 OAP63640.1 - 0.06 13.7 22.6 4.6 7.6 0.1 7.0 8 0 0 8 8 8 0 Zinc-finger double-stranded RNA-binding zf-C2H2_9 PF16293.5 OAP63640.1 - 0.075 12.9 0.8 1.7 8.6 0.1 3.6 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) zf-met PF12874.7 OAP63640.1 - 0.23 11.9 0.1 0.23 11.9 0.1 6.4 8 0 0 8 8 7 0 Zinc-finger of C2H2 type RNA_pol_Rpb6 PF01192.22 OAP63641.1 - 7.8e-17 60.9 0.6 1.7e-16 59.9 0.1 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb6 Pox_RNA_Pol_19 PF05320.12 OAP63641.1 - 0.074 13.0 0.1 0.094 12.7 0.1 1.1 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Hydrolase_4 PF12146.8 OAP63643.1 - 3.1e-42 144.5 0.0 3.9e-42 144.2 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OAP63643.1 - 1.5e-13 51.9 0.1 1.9e-13 51.5 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAP63643.1 - 1.3e-10 41.3 0.5 2.4e-10 40.5 0.5 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.18 OAP63643.1 - 1.4e-05 24.8 0.0 0.05 13.1 0.0 2.3 2 0 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 OAP63643.1 - 0.00023 21.0 0.0 2.6 7.8 0.0 3.2 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 OAP63643.1 - 0.0017 17.9 0.0 1.2 8.6 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Esterase PF00756.20 OAP63643.1 - 0.0031 17.2 0.0 0.0061 16.2 0.0 1.5 1 0 0 1 1 1 1 Putative esterase Chlorophyllase2 PF12740.7 OAP63643.1 - 0.0055 15.7 0.0 0.014 14.3 0.0 1.6 1 1 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 OAP63643.1 - 0.053 12.5 0.2 0.25 10.3 0.2 1.9 1 1 0 1 1 1 0 Chlorophyllase DUF915 PF06028.11 OAP63643.1 - 0.063 12.6 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) DUF1749 PF08538.10 OAP63643.1 - 0.073 12.1 0.0 0.15 11.1 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1749) Prok-E2_B PF14461.6 OAP63643.1 - 0.15 11.8 0.0 0.39 10.4 0.0 1.7 1 0 0 1 1 1 0 Prokaryotic E2 family B WD40 PF00400.32 OAP63644.1 - 0.00031 21.5 3.9 8.2 7.5 0.0 4.6 4 1 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAP63644.1 - 0.11 12.8 0.0 0.31 11.4 0.0 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain SNase PF00565.17 OAP63645.1 - 3.5e-24 85.4 0.2 5.5e-24 84.7 0.2 1.3 1 0 0 1 1 1 1 Staphylococcal nuclease homologue SDA1 PF05285.12 OAP63646.1 - 0.065 12.7 8.6 0.079 12.4 8.6 1.2 1 0 0 1 1 1 0 SDA1 TauD PF02668.16 OAP63647.1 - 1.2e-61 208.9 0.1 1.4e-61 208.6 0.1 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family NCBP3 PF10309.9 OAP63648.1 - 2e-19 69.2 0.7 3.3e-19 68.5 0.7 1.3 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 RNA_bind PF08675.11 OAP63648.1 - 0.012 15.6 0.0 0.022 14.8 0.0 1.4 1 0 0 1 1 1 0 RNA binding domain Vta1 PF04652.16 OAP63649.1 - 1.1e-53 181.1 1.9 1.1e-53 181.1 1.9 1.4 2 0 0 2 2 2 1 Vta1 like Vta1_C PF18097.1 OAP63649.1 - 2.7e-15 55.8 0.2 9.6e-15 54.0 0.0 2.0 2 0 0 2 2 2 1 Vta1 C-terminal domain MMR_HSR1 PF01926.23 OAP63650.1 - 0.00051 20.1 0.0 0.0012 18.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 OAP63650.1 - 0.0039 17.6 1.8 0.028 14.8 0.6 2.5 1 1 1 2 2 2 1 AAA ATPase domain AIG1 PF04548.16 OAP63650.1 - 0.0043 16.4 0.0 0.0085 15.4 0.0 1.4 1 0 0 1 1 1 1 AIG1 family AAA_25 PF13481.6 OAP63650.1 - 0.016 14.8 0.9 0.032 13.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 OAP63650.1 - 0.018 14.7 0.0 0.036 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 OAP63650.1 - 0.023 15.0 0.4 0.093 13.0 0.4 2.1 1 1 0 1 1 1 0 AAA domain T2SSE PF00437.20 OAP63650.1 - 0.025 13.7 0.1 0.039 13.0 0.1 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein MeaB PF03308.16 OAP63650.1 - 0.028 13.4 1.3 0.07 12.1 0.1 2.2 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_7 PF12775.7 OAP63650.1 - 0.031 13.8 0.1 0.053 13.0 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF2075 PF09848.9 OAP63650.1 - 0.036 13.3 0.2 0.062 12.5 0.2 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_29 PF13555.6 OAP63650.1 - 0.043 13.6 0.8 0.089 12.5 0.8 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 OAP63650.1 - 0.044 14.3 0.2 0.11 13.0 0.2 1.6 1 0 0 1 1 1 0 ABC transporter AAA_23 PF13476.6 OAP63650.1 - 0.044 14.3 1.1 0.094 13.2 1.1 1.5 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 OAP63650.1 - 0.046 13.6 0.1 0.085 12.8 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase Ploopntkinase3 PF18751.1 OAP63650.1 - 0.068 13.1 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 Zeta_toxin PF06414.12 OAP63650.1 - 0.1 11.9 0.1 0.25 10.6 0.1 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.6 OAP63650.1 - 0.13 12.8 0.1 0.36 11.4 0.1 1.8 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 OAP63650.1 - 0.14 11.8 0.0 0.33 10.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Kinesin PF00225.23 OAP63650.1 - 0.17 10.8 0.1 0.25 10.2 0.1 1.1 1 0 0 1 1 1 0 Kinesin motor domain zf-C2H2_4 PF13894.6 OAP63651.1 - 8.6e-13 48.0 24.6 0.27 12.2 0.4 7.4 7 0 0 7 7 7 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OAP63651.1 - 1.2e-08 35.0 19.9 0.0039 17.4 1.4 6.3 7 0 0 7 7 6 3 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 OAP63651.1 - 6.1e-08 32.7 28.8 0.016 15.7 0.9 7.1 7 0 0 7 7 7 3 Zinc finger, C2H2 type zf-met PF12874.7 OAP63651.1 - 1.7e-07 31.4 17.9 0.16 12.4 0.7 6.4 6 0 0 6 6 6 4 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 OAP63651.1 - 4.1e-06 26.4 9.6 0.4 10.5 0.0 5.7 6 0 0 6 6 6 2 zinc-finger C2H2-type zf-C2H2_2 PF12756.7 OAP63651.1 - 0.00025 21.3 4.7 0.00025 21.3 4.7 4.9 2 1 3 5 5 5 3 C2H2 type zinc-finger (2 copies) zf-C2H2_3rep PF18868.1 OAP63651.1 - 0.0059 17.3 11.0 2.5 8.8 0.0 4.6 2 1 2 4 4 4 1 Zinc finger C2H2-type, 3 repeats HypA PF01155.19 OAP63651.1 - 0.013 15.5 15.2 0.46 10.5 0.6 4.4 2 1 2 4 4 4 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA GATA PF00320.27 OAP63651.1 - 0.089 12.4 4.8 1.2 8.8 0.1 3.5 3 0 0 3 3 3 0 GATA zinc finger zf-C2H2_6 PF13912.6 OAP63651.1 - 0.099 12.7 0.1 0.099 12.7 0.1 5.5 7 0 0 7 7 7 0 C2H2-type zinc finger Cript PF10235.9 OAP63651.1 - 0.22 12.1 0.3 0.22 12.1 0.3 3.3 2 1 2 4 4 4 0 Microtubule-associated protein CRIPT zf-H2C2_2 PF13465.6 OAP63651.1 - 0.26 11.8 12.0 11 6.7 0.2 5.3 4 0 0 4 4 4 0 Zinc-finger double domain DUF2256 PF10013.9 OAP63651.1 - 0.3 11.2 16.1 36 4.6 0.1 6.6 7 0 0 7 7 7 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2H2_9 PF16293.5 OAP63651.1 - 0.47 10.3 12.5 0.31 10.9 0.4 4.4 3 1 2 5 5 5 0 C2H2 type zinc-finger (1 copy) DZR PF12773.7 OAP63651.1 - 0.78 9.8 21.8 1.8e+04 -8.4 21.8 4.6 1 1 0 1 1 0 0 Double zinc ribbon Zn-ribbon_8 PF09723.10 OAP63651.1 - 1.8 8.7 25.3 12 6.1 0.9 5.7 3 1 3 6 6 6 0 Zinc ribbon domain Rep_fac-A_C PF08646.10 OAP63651.1 - 3 7.6 6.4 8.3 6.1 0.1 3.5 4 1 0 4 4 4 0 Replication factor-A C terminal domain TPR_2 PF07719.17 OAP63652.1 - 9.1e-08 31.7 1.5 0.0054 16.8 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 OAP63652.1 - 3.6e-07 29.7 1.5 0.00028 20.6 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 OAP63652.1 - 0.00078 20.0 1.1 3.3 8.4 2.2 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat SRP_TPR_like PF17004.5 OAP63652.1 - 0.0022 18.0 0.5 0.0054 16.7 0.5 1.7 1 1 0 1 1 1 1 Putative TPR-like repeat TPR_11 PF13414.6 OAP63652.1 - 0.0054 16.4 0.9 0.013 15.2 0.1 2.0 2 1 0 2 2 2 1 TPR repeat TPR_19 PF14559.6 OAP63652.1 - 0.0085 16.6 0.8 0.61 10.6 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 OAP63652.1 - 0.0093 16.2 0.3 0.028 14.7 0.0 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 OAP63652.1 - 0.0099 16.1 4.5 0.042 14.1 4.0 2.2 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 ComX PF05952.12 OAP63652.1 - 0.033 14.1 0.0 0.057 13.4 0.0 1.4 1 0 0 1 1 1 0 Bacillus competence pheromone ComX TPR_7 PF13176.6 OAP63652.1 - 0.068 13.2 0.9 3.4 7.9 0.1 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Glyoxalase PF00903.25 OAP63653.1 - 2.6e-15 56.7 0.1 3.4e-15 56.4 0.1 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 OAP63653.1 - 0.0025 18.6 0.0 0.004 17.9 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.6 OAP63653.1 - 0.028 14.7 0.0 0.11 12.8 0.0 1.9 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Hanta_G2 PF01561.16 OAP63653.1 - 0.14 10.8 0.1 0.18 10.4 0.1 1.1 1 0 0 1 1 1 0 Hantavirus glycoprotein G2 EthD PF07110.11 OAP63654.1 - 4.5e-19 69.4 0.2 8.3e-19 68.5 0.2 1.4 1 1 0 1 1 1 1 EthD domain MmlI PF09448.10 OAP63654.1 - 5.9e-12 46.0 0.1 9e-12 45.5 0.1 1.3 1 1 0 1 1 1 1 Methylmuconolactone methyl-isomerase SpoIIE PF07228.12 OAP63655.1 - 1.1e-09 38.5 0.1 5.5e-09 36.2 0.0 2.0 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 OAP63655.1 - 1.1e-07 31.8 0.0 0.0029 17.3 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 OAP63655.1 - 2.2e-07 30.7 0.0 4.9e-07 29.6 0.0 1.4 1 1 0 1 1 1 1 Protein phosphatase 2C p450 PF00067.22 OAP63656.1 - 5.7e-97 325.4 0.0 6.9e-97 325.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PCI PF01399.27 OAP63657.1 - 9e-14 51.9 0.0 2.6e-13 50.4 0.0 1.8 2 0 0 2 2 2 1 PCI domain TPR_19 PF14559.6 OAP63657.1 - 0.29 11.7 6.7 0.22 12.1 0.4 3.1 2 1 0 2 2 2 0 Tetratricopeptide repeat Aldedh PF00171.22 OAP63658.1 - 1.5e-148 495.2 0.0 1.6e-148 495.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF2188 PF09954.9 OAP63658.1 - 0.04 14.1 0.0 0.09 12.9 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2188) GFO_IDH_MocA PF01408.22 OAP63659.1 - 2.1e-18 67.3 0.0 4.5e-18 66.2 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold ABC_membrane PF00664.23 OAP63660.1 - 1.3e-90 303.8 37.5 5.2e-48 164.1 15.2 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 OAP63660.1 - 9.9e-69 230.2 0.0 5.1e-33 114.5 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 OAP63660.1 - 1.1e-12 47.9 1.0 0.00017 21.1 0.5 3.9 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 OAP63660.1 - 3.3e-09 36.1 1.8 0.0063 15.4 0.0 3.9 4 0 0 4 4 4 2 Predicted ATPase of the ABC class RsgA_GTPase PF03193.16 OAP63660.1 - 4.9e-09 36.3 0.0 0.0014 18.6 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 OAP63660.1 - 3e-08 34.2 2.9 0.0029 18.0 0.1 2.9 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 OAP63660.1 - 1.3e-07 32.0 0.6 0.06 13.6 0.2 3.8 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.6 OAP63660.1 - 2.2e-07 30.5 0.3 0.017 14.9 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 OAP63660.1 - 6e-07 29.6 0.5 1.3 8.7 0.0 4.1 3 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 OAP63660.1 - 8.3e-06 25.5 0.0 0.076 12.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 OAP63660.1 - 0.00015 22.0 0.8 0.68 10.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 OAP63660.1 - 0.00017 21.5 0.0 0.3 10.7 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain SbcCD_C PF13558.6 OAP63660.1 - 0.00054 20.1 4.5 0.25 11.6 0.6 4.2 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.14 OAP63660.1 - 0.0007 19.6 0.6 4.3 7.3 0.0 3.8 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 OAP63660.1 - 0.0038 17.4 0.0 3.1 7.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 OAP63660.1 - 0.0052 16.9 0.2 7 6.8 0.0 3.4 4 0 0 4 4 2 0 50S ribosome-binding GTPase AAA_30 PF13604.6 OAP63660.1 - 0.0073 16.0 2.6 4.7 6.9 0.1 3.9 2 2 0 2 2 2 1 AAA domain Dala_Dala_lig_N PF01820.21 OAP63660.1 - 0.012 16.1 0.0 0.91 10.0 0.0 2.5 2 0 0 2 2 2 0 D-ala D-ala ligase N-terminus AAA_23 PF13476.6 OAP63660.1 - 0.015 15.8 0.2 4 7.9 0.1 2.4 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.20 OAP63660.1 - 0.017 14.3 0.0 1 8.4 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit RNA_helicase PF00910.22 OAP63660.1 - 0.019 15.4 0.1 8.8 6.8 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_14 PF13173.6 OAP63660.1 - 0.024 14.7 0.0 3.7 7.6 0.0 3.4 4 0 0 4 4 3 0 AAA domain Zeta_toxin PF06414.12 OAP63660.1 - 0.025 13.9 0.2 9.7 5.4 0.0 2.8 3 0 0 3 3 3 0 Zeta toxin AAA_18 PF13238.6 OAP63660.1 - 0.034 14.7 0.0 9.3 6.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 OAP63660.1 - 0.046 13.2 0.0 8.8 5.8 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF815 PF05673.13 OAP63660.1 - 0.047 12.8 0.0 5.3 6.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) ATP-synt_ab PF00006.25 OAP63660.1 - 0.05 13.3 0.0 3.3 7.3 0.0 2.7 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Rad17 PF03215.15 OAP63660.1 - 0.052 13.5 0.2 12 5.7 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain NACHT PF05729.12 OAP63660.1 - 0.054 13.4 0.4 12 5.7 0.1 2.9 2 0 0 2 2 2 0 NACHT domain AAA PF00004.29 OAP63660.1 - 0.072 13.5 1.5 88 3.5 0.3 4.3 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 OAP63660.1 - 0.14 11.3 0.2 7.5 5.7 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain SRF-TF PF00319.18 OAP63661.1 - 2.3e-24 84.6 0.3 3.4e-24 84.1 0.3 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) DUF1708 PF08101.11 OAP63662.1 - 2.7e-169 563.9 0.0 3.6e-169 563.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) PX PF00787.24 OAP63663.1 - 3.2e-21 75.4 0.0 5.5e-21 74.7 0.0 1.2 1 0 0 1 1 1 1 PX domain Pkinase PF00069.25 OAP63665.1 - 2.1e-45 155.1 0.0 3.1e-45 154.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP63665.1 - 6.7e-18 64.9 0.0 1e-17 64.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 OAP63665.1 - 0.0029 17.3 0.2 0.0052 16.4 0.2 1.4 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 OAP63665.1 - 0.0087 15.4 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OAP63665.1 - 0.019 14.3 0.3 0.039 13.3 0.3 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OAP63665.1 - 0.03 14.2 0.1 0.41 10.5 0.1 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OAP63665.1 - 0.12 11.1 0.1 0.35 9.6 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase UPF0261 PF06792.11 OAP63666.1 - 3.5e-158 526.8 1.6 4e-158 526.6 1.6 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0261) PEP_hydrolase PF09370.10 OAP63667.1 - 9.6e-136 451.2 0.4 1.1e-135 451.1 0.4 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate hydrolase-like NMO PF03060.15 OAP63667.1 - 2.3e-05 24.0 0.1 3.1e-05 23.5 0.1 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase DUF4287 PF14117.6 OAP63667.1 - 0.13 12.4 0.1 1 9.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4287) RNA_pol_Rpb4 PF03874.16 OAP63669.1 - 2.2e-15 57.1 0.1 3.2e-15 56.6 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb4 Met_10 PF02475.16 OAP63671.1 - 2.5e-64 216.7 0.0 3.9e-64 216.1 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein DUF5063 PF16702.5 OAP63671.1 - 0.13 12.7 0.3 0.24 11.8 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5063) Cupin_2 PF07883.11 OAP63672.1 - 0.0006 19.5 1.5 0.0016 18.1 0.0 2.1 2 0 0 2 2 2 1 Cupin domain Cupin_3 PF05899.12 OAP63672.1 - 0.0029 17.3 0.0 0.006 16.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_1 PF00190.22 OAP63672.1 - 0.027 14.1 0.5 0.039 13.6 0.0 1.5 2 0 0 2 2 2 0 Cupin Cupin_6 PF12852.7 OAP63672.1 - 0.073 12.8 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Cupin AraC_binding PF02311.19 OAP63672.1 - 0.16 11.9 0.0 0.16 11.9 0.0 1.5 2 0 0 2 2 2 0 AraC-like ligand binding domain 2OG-FeII_Oxy_2 PF13532.6 OAP63673.1 - 6.8e-27 94.9 0.0 1.2e-26 94.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily SPATA6 PF14909.6 OAP63673.1 - 0.18 11.9 0.0 0.29 11.3 0.0 1.3 1 0 0 1 1 1 0 Spermatogenesis-assoc protein 6 DUF2235 PF09994.9 OAP63675.1 - 1.3e-72 244.6 0.0 1.6e-72 244.3 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) PhoD PF09423.10 OAP63676.1 - 3.3e-07 29.6 0.0 4e-06 26.1 0.0 2.2 1 1 0 1 1 1 1 PhoD-like phosphatase Peptidase_S8 PF00082.22 OAP63677.1 - 4e-32 111.7 1.3 5.7e-32 111.2 1.3 1.2 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 OAP63677.1 - 1.3e-26 92.4 0.2 2.4e-26 91.5 0.2 1.5 1 0 0 1 1 1 1 Proprotein convertase P-domain S8_pro-domain PF16470.5 OAP63677.1 - 0.00025 21.8 6.8 0.0037 18.0 6.8 2.4 1 1 0 1 1 1 1 Peptidase S8 pro-domain SAS4 PF15460.6 OAP63678.1 - 1.2e-30 105.5 6.6 2.5e-30 104.5 6.6 1.5 1 0 0 1 1 1 1 Something about silencing, SAS, complex subunit 4 DGF-1_C PF11040.8 OAP63678.1 - 0.1 12.6 1.1 0.26 11.3 1.1 1.7 1 0 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus Peptidase_S41 PF03572.18 OAP63679.1 - 1.4e-07 31.3 0.0 6.3e-07 29.1 0.0 2.0 1 1 0 1 1 1 1 Peptidase family S41 A_deaminase PF00962.22 OAP63680.1 - 9.6e-120 399.8 0.1 1.3e-119 399.3 0.1 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase DOR PF14839.6 OAP63682.1 - 0.076 13.0 7.5 0.14 12.1 7.5 1.5 1 0 0 1 1 1 0 DOR family DUF4407 PF14362.6 OAP63682.1 - 0.93 8.8 13.7 1.3 8.3 13.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Cyclin PF08613.11 OAP63683.1 - 6.3e-38 130.7 0.0 1.2e-37 129.8 0.0 1.4 1 0 0 1 1 1 1 Cyclin Sugar_tr PF00083.24 OAP63684.1 - 1.8e-80 271.0 18.0 2.1e-80 270.8 18.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP63684.1 - 8e-14 51.3 40.0 1.3e-09 37.5 6.0 2.3 1 1 2 3 3 3 3 Major Facilitator Superfamily MFS_1_like PF12832.7 OAP63684.1 - 0.00023 20.1 5.2 0.00028 19.9 3.9 1.7 2 0 0 2 2 2 1 MFS_1 like family Nuc_H_symport PF03825.16 OAP63684.1 - 0.00052 19.1 0.7 0.00098 18.2 0.7 1.4 1 0 0 1 1 1 1 Nucleoside H+ symporter PsbT PF01405.17 OAP63684.1 - 1.6 8.6 4.0 4 7.3 4.0 1.7 1 0 0 1 1 1 0 Photosystem II reaction centre T protein ProRS-C_1 PF09180.11 OAP63687.1 - 0.11 12.7 0.9 0.27 11.5 0.9 1.6 1 0 0 1 1 1 0 Prolyl-tRNA synthetase, C-terminal SLH PF00395.20 OAP63687.1 - 0.16 12.0 0.1 5.5 7.1 0.1 2.4 2 0 0 2 2 2 0 S-layer homology domain zf-C2H2_3rep PF18868.1 OAP63687.1 - 0.75 10.5 3.3 1.3 9.7 2.1 2.1 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats Mito_carr PF00153.27 OAP63689.1 - 6.7e-65 215.1 1.1 6.3e-20 70.9 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DRMBL PF07522.14 OAP63690.1 - 2.5e-35 121.0 0.0 5.1e-35 120.0 0.0 1.6 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 OAP63690.1 - 0.002 17.7 0.0 0.005 16.4 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain LSM PF01423.22 OAP63691.1 - 1.9e-17 62.7 0.3 2.3e-17 62.4 0.3 1.1 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 OAP63691.1 - 0.067 12.9 0.0 0.09 12.4 0.0 1.3 1 0 0 1 1 1 0 Hfq protein Abhydro_lipase PF04083.16 OAP63692.1 - 6.2e-20 70.6 0.0 2.1e-19 68.9 0.0 2.0 2 0 0 2 2 2 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 OAP63692.1 - 3.9e-07 30.0 0.0 6.6e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAP63692.1 - 5.4e-05 22.6 0.0 0.00019 20.8 0.0 1.9 2 0 0 2 2 2 1 Serine aminopeptidase, S33 AA_permease_2 PF13520.6 OAP63693.1 - 3.1e-63 214.1 46.3 3.8e-63 213.8 46.3 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAP63693.1 - 4.1e-13 48.7 36.3 5.5e-13 48.3 36.3 1.2 1 0 0 1 1 1 1 Amino acid permease Peptidase_S10 PF00450.22 OAP63694.1 - 1.7e-71 241.8 0.0 2.5e-71 241.3 0.0 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase VRR_NUC PF08774.11 OAP63695.1 - 7.9e-19 67.7 0.0 2.2e-18 66.3 0.0 1.8 1 0 0 1 1 1 1 VRR-NUC domain Mito_carr PF00153.27 OAP63696.1 - 4.5e-74 244.5 0.0 6.9e-25 86.8 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_6 PF13405.6 OAP63696.1 - 7.4e-18 62.9 1.1 1.5e-07 30.8 0.1 5.9 6 0 0 6 6 6 2 EF-hand domain EF-hand_7 PF13499.6 OAP63696.1 - 6.2e-17 61.8 7.0 2.8e-09 37.3 0.4 4.9 3 2 3 6 6 6 3 EF-hand domain pair EF-hand_1 PF00036.32 OAP63696.1 - 1.1e-13 49.6 3.6 4.2e-07 29.1 0.1 5.6 6 0 0 6 6 6 2 EF hand EF-hand_5 PF13202.6 OAP63696.1 - 2.3e-07 30.0 3.4 0.00045 19.6 0.1 4.9 5 0 0 5 5 5 1 EF hand EF-hand_8 PF13833.6 OAP63696.1 - 2.4e-05 24.1 0.2 3.6 7.5 0.0 4.7 4 1 0 4 4 4 2 EF-hand domain pair EF-hand_9 PF14658.6 OAP63696.1 - 0.00034 20.9 0.1 2.3 8.6 0.0 3.6 3 1 0 3 3 3 2 EF-hand domain Myb_DNA-bind_6 PF13921.6 OAP63697.1 - 0.00016 21.9 0.6 0.00037 20.7 0.6 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 OAP63697.1 - 0.00052 20.2 0.4 0.0015 18.6 0.1 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain HEPN-like_int PF18867.1 OAP63697.1 - 0.24 11.3 0.0 0.45 10.4 0.0 1.4 1 0 0 1 1 1 0 HEPN-like integron domain Herpes_BLLF1 PF05109.13 OAP63698.1 - 0.97 7.3 9.9 1.2 7.1 9.9 1.0 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) RRM_1 PF00076.22 OAP63699.1 - 1.2e-20 73.1 0.0 1.8e-20 72.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OAP63699.1 - 0.0006 19.4 0.0 0.00085 18.9 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-HC5HC2H_2 PF13832.6 OAP63700.1 - 2.7e-33 114.4 1.8 2.7e-33 114.4 1.8 2.4 2 0 0 2 2 2 1 PHD-zinc-finger like domain EPL1 PF10513.9 OAP63700.1 - 1.3e-29 103.6 0.1 7.3e-29 101.2 0.0 2.4 3 0 0 3 3 3 1 Enhancer of polycomb-like zf-HC5HC2H PF13771.6 OAP63700.1 - 4.8e-26 90.9 0.5 4.8e-26 90.9 0.5 2.9 2 1 1 3 3 3 1 PHD-like zinc-binding domain PHD_2 PF13831.6 OAP63700.1 - 1.8e-14 53.0 2.9 5.2e-14 51.5 2.9 1.9 1 0 0 1 1 1 1 PHD-finger PHD PF00628.29 OAP63700.1 - 2.5e-10 40.1 19.7 9.2e-09 35.1 9.6 2.7 2 0 0 2 2 2 2 PHD-finger zf-PHD-like PF15446.6 OAP63700.1 - 0.0086 15.7 2.1 0.025 14.2 2.1 1.8 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain Prok-RING_1 PF14446.6 OAP63700.1 - 0.1 12.5 14.6 1.1 9.2 7.0 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Ribosomal_S13_N PF08069.12 OAP63702.1 - 2.4e-28 97.9 0.1 3.7e-28 97.3 0.1 1.3 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 OAP63702.1 - 2.9e-15 56.3 0.3 4e-15 55.8 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.18 OAP63702.1 - 0.06 13.3 0.1 0.14 12.1 0.0 1.6 2 0 0 2 2 2 0 'Paired box' domain Dpy-30 PF05186.13 OAP63703.1 - 0.0035 17.0 0.0 0.013 15.2 0.0 1.9 1 1 0 1 1 1 1 Dpy-30 motif SRP-alpha_N PF04086.13 OAP63704.1 - 2 8.2 9.7 2.8 7.8 9.7 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Fungal_trans_2 PF11951.8 OAP63706.1 - 4.5e-39 134.4 0.0 8.7e-39 133.4 0.0 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.25 OAP63707.1 - 1.6e-14 53.9 0.0 1.3e-13 50.9 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 OAP63707.1 - 2.1e-07 31.0 0.0 3.4e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAP63707.1 - 0.00025 20.6 0.0 0.0019 17.7 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAP63707.1 - 0.00031 20.2 0.0 0.0018 17.7 0.0 1.9 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 OAP63707.1 - 0.021 14.0 0.0 0.12 11.5 0.0 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 OAP63707.1 - 0.049 12.8 0.0 0.25 10.5 0.0 2.0 2 0 0 2 2 2 0 Male sterility protein AAA PF00004.29 OAP63708.1 - 4e-53 179.4 0.0 4e-43 147.0 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OAP63708.1 - 4.5e-06 26.4 3.5 7.5e-05 22.5 0.0 2.9 3 0 0 3 3 2 1 AAA+ lid domain AAA_16 PF13191.6 OAP63708.1 - 0.00012 22.5 0.1 0.025 15.0 0.0 3.2 3 0 0 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 OAP63708.1 - 0.00026 20.8 0.0 0.00065 19.5 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 OAP63708.1 - 0.00037 20.9 0.0 0.018 15.5 0.0 2.7 2 0 0 2 2 2 1 RNA helicase Parvo_NS1 PF01057.17 OAP63708.1 - 0.0013 17.9 0.0 0.0024 17.0 0.0 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_2 PF07724.14 OAP63708.1 - 0.0026 17.9 0.0 0.0091 16.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 OAP63708.1 - 0.003 17.3 0.0 0.0083 15.9 0.0 1.6 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_22 PF13401.6 OAP63708.1 - 0.0057 16.9 0.3 0.054 13.8 0.0 2.7 3 1 0 3 3 3 1 AAA domain TIP49 PF06068.13 OAP63708.1 - 0.0087 15.3 0.0 0.015 14.5 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain ATPase PF06745.13 OAP63708.1 - 0.014 14.8 0.0 0.028 13.8 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_5 PF07728.14 OAP63708.1 - 0.014 15.4 0.0 0.14 12.2 0.0 2.6 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 OAP63708.1 - 0.028 13.8 0.0 0.056 12.8 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 OAP63708.1 - 0.058 13.0 0.0 0.24 11.0 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 OAP63708.1 - 0.063 13.8 0.0 0.14 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 OAP63708.1 - 0.067 13.2 0.0 2 8.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 OAP63708.1 - 0.068 12.6 0.0 0.19 11.2 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein AAA_7 PF12775.7 OAP63708.1 - 0.094 12.2 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region TsaE PF02367.17 OAP63708.1 - 0.1 12.6 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 OAP63708.1 - 0.13 12.5 0.0 0.32 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 OAP63708.1 - 0.14 12.3 0.0 0.46 10.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain K_oxygenase PF13434.6 OAP63709.1 - 2.4e-113 378.7 0.0 2.8e-113 378.5 0.0 1.0 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 OAP63709.1 - 8.5e-07 29.1 0.0 0.0026 17.8 0.0 3.3 3 0 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 OAP63709.1 - 8.3e-06 25.2 0.0 0.00044 19.6 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAP63709.1 - 1.2e-05 24.8 0.0 0.002 17.5 0.0 2.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase AMP-binding PF00501.28 OAP63710.1 - 5e-207 687.6 0.0 1.1e-70 238.4 0.0 5.1 5 1 1 6 6 6 4 AMP-binding enzyme Condensation PF00668.20 OAP63710.1 - 7.6e-170 565.5 0.0 4.2e-33 114.7 0.0 9.2 6 3 1 8 8 8 8 Condensation domain PP-binding PF00550.25 OAP63710.1 - 1.1e-55 185.9 4.5 7.3e-09 35.9 0.0 7.1 7 0 0 7 7 7 6 Phosphopantetheine attachment site AMP-binding_C PF13193.6 OAP63710.1 - 2.5e-14 54.0 0.0 2.5e-05 25.2 0.0 3.9 3 0 0 3 3 3 3 AMP-binding enzyme C-terminal domain AbiEi_3 PF11459.8 OAP63710.1 - 0.14 11.9 0.0 0.42 10.3 0.0 1.8 1 0 0 1 1 1 0 Transcriptional regulator, AbiEi antitoxin, Type IV TA system MFS_1 PF07690.16 OAP63712.1 - 6.9e-37 127.2 25.0 9.5e-37 126.7 25.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.16 OAP63713.1 - 8.2e-21 74.3 31.6 8.2e-21 74.3 31.6 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily ELMO_CED12 PF04727.13 OAP63714.1 - 2.8e-47 161.1 0.0 4.4e-47 160.5 0.0 1.3 1 0 0 1 1 1 1 ELMO/CED-12 family PH_12 PF16457.5 OAP63714.1 - 3.2e-34 118.3 0.0 8.1e-34 117.0 0.0 1.7 2 0 0 2 2 2 1 Pleckstrin homology domain DUF3361 PF11841.8 OAP63714.1 - 0.026 14.5 0.6 0.055 13.4 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3361) RPN1_RPN2_N PF17781.1 OAP63714.1 - 0.13 11.6 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 RPN1/RPN2 N-terminal domain DUF3361 PF11841.8 OAP63715.1 - 9.4e-06 25.6 0.0 1.4e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3361) SUI1 PF01253.22 OAP63716.1 - 5e-25 87.8 0.0 1.4e-24 86.4 0.0 1.7 1 0 0 1 1 1 1 Translation initiation factor SUI1 TnpV PF14198.6 OAP63716.1 - 0.03 14.3 1.5 0.048 13.6 1.5 1.4 1 0 0 1 1 1 0 Transposon-encoded protein TnpV tRNA_edit PF04073.15 OAP63716.1 - 0.044 13.9 1.7 0.069 13.2 1.7 1.3 1 0 0 1 1 1 0 Aminoacyl-tRNA editing domain DUF1752 PF08550.10 OAP63717.1 - 3.6e-08 33.1 2.0 7e-08 32.2 2.0 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) GPI-anchored PF10342.9 OAP63718.1 - 2.3e-14 53.9 0.1 2.3e-14 53.9 0.1 2.8 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF2076 PF09849.9 OAP63718.1 - 0.048 13.7 4.3 0.066 13.3 4.3 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) DUF1652 PF07865.11 OAP63718.1 - 0.1 12.4 0.0 0.24 11.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1652) Shisa PF13908.6 OAP63718.1 - 0.47 10.7 5.4 0.36 11.0 3.8 1.7 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Macoilin PF09726.9 OAP63718.1 - 0.6 8.6 11.0 0.65 8.5 11.0 1.0 1 0 0 1 1 1 0 Macoilin family SOG2 PF10428.9 OAP63718.1 - 1.4 8.1 19.8 1.5 8.0 19.8 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein SPX PF03105.19 OAP63718.1 - 1.7 8.5 10.9 1.9 8.3 10.9 1.1 1 0 0 1 1 1 0 SPX domain DHHW PF14286.6 OAP63718.1 - 3.6 6.8 9.0 4.7 6.4 9.0 1.1 1 0 0 1 1 1 0 DHHW protein Apt1 PF10351.9 OAP63718.1 - 4.2 6.1 14.0 5.1 5.8 14.0 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain CENP-U PF13097.6 OAP63718.1 - 4.6 7.2 9.8 6.5 6.7 9.8 1.2 1 0 0 1 1 1 0 CENP-A nucleosome associated complex (NAC) subunit Sortilin-Vps10 PF15902.5 OAP63720.1 - 2.1e-294 976.0 0.6 3e-153 510.8 0.3 2.1 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 OAP63720.1 - 5.9e-96 319.6 12.4 3.2e-49 167.5 2.4 2.4 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 OAP63720.1 - 8.1e-14 49.3 35.4 0.23 11.6 0.1 11.3 11 0 0 11 11 11 6 BNR/Asp-box repeat PSII_BNR PF14870.6 OAP63720.1 - 3.8e-08 32.9 0.4 0.073 12.3 0.0 5.2 4 2 1 5 5 5 2 Photosynthesis system II assembly factor YCF48 BNR_2 PF13088.6 OAP63720.1 - 0.0085 15.4 8.1 9.2 5.5 0.0 7.0 4 3 0 5 5 5 1 BNR repeat-like domain DUF2167 PF09935.9 OAP63720.1 - 0.11 11.7 0.1 11 5.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2167) CHB_HEX_C PF03174.13 OAP63720.1 - 0.17 11.9 2.2 5.1 7.1 0.0 3.9 6 0 0 6 6 6 0 Chitobiase/beta-hexosaminidase C-terminal domain BNR_6 PF15899.5 OAP63720.1 - 3.7 7.9 10.7 1.7e+02 2.7 0.0 6.3 6 0 0 6 6 6 0 BNR-Asp box repeat CsbD PF05532.12 OAP63721.1 - 0.00027 20.8 1.4 0.0004 20.2 1.4 1.3 1 0 0 1 1 1 1 CsbD-like HU-CCDC81_bac_2 PF18175.1 OAP63721.1 - 0.037 13.9 0.0 0.06 13.2 0.0 1.3 1 0 0 1 1 1 0 CCDC81-like prokaryotic HU domain 2 PqqD PF05402.12 OAP63721.1 - 0.1 12.9 0.1 0.17 12.2 0.1 1.3 1 0 0 1 1 1 0 Coenzyme PQQ synthesis protein D (PqqD) DUF2791 PF10923.8 OAP63722.1 - 0.063 12.1 0.1 0.086 11.7 0.1 1.1 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) DUF2716 PF10898.8 OAP63722.1 - 0.11 12.9 0.4 0.22 11.9 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2716) Abhydrolase_3 PF07859.13 OAP63723.1 - 1.4e-12 47.9 0.1 3.4e-09 36.9 0.0 3.6 2 1 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 OAP63723.1 - 0.25 10.2 0.0 0.42 9.4 0.0 1.3 1 0 0 1 1 1 0 Steryl acetyl hydrolase NUFIP1 PF10453.9 OAP63724.1 - 2.6e-08 33.6 11.0 1.2e-07 31.4 10.9 2.2 1 1 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-CCCH_4 PF18044.1 OAP63724.1 - 9e-06 25.4 2.8 1.4e-05 24.8 2.8 1.3 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 OAP63724.1 - 8.2e-05 22.5 6.6 0.00013 21.9 6.6 1.3 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 OAP63724.1 - 8.7e-05 22.3 1.3 0.00015 21.5 1.3 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) VSG_B PF13206.6 OAP63724.1 - 0.093 12.0 12.6 0.15 11.3 12.6 1.4 1 0 0 1 1 1 0 Trypanosomal VSG domain Torus PF16131.5 OAP63724.1 - 0.45 11.2 0.0 0.45 11.2 0.0 2.7 3 1 0 3 3 3 0 Torus domain DUF4551 PF15087.6 OAP63724.1 - 3.2 6.5 25.5 0.77 8.5 16.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4551) Adenosine_kin PF04008.14 OAP63725.1 - 2.5e-73 245.0 0.0 3e-73 244.7 0.0 1.1 1 0 0 1 1 1 1 Adenosine specific kinase RNA_pol_Rbc25 PF08292.12 OAP63726.1 - 3.9e-34 117.7 0.0 7.5e-34 116.8 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 OAP63726.1 - 5.3e-15 55.5 0.0 1.2e-14 54.4 0.0 1.6 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 OAP63726.1 - 0.011 16.1 0.0 0.024 15.0 0.0 1.6 1 0 0 1 1 1 0 S1 RNA binding domain SeleniumBinding PF11524.8 OAP63726.1 - 0.067 13.6 0.0 0.1 13.1 0.0 1.3 1 0 0 1 1 1 0 Selenium binding protein Cys_Met_Meta_PP PF01053.20 OAP63727.1 - 7.7e-140 465.7 0.0 8.8e-140 465.6 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 OAP63727.1 - 8.8e-09 35.0 0.1 1.3e-08 34.4 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 OAP63727.1 - 4.2e-06 26.0 0.3 7.4e-06 25.2 0.1 1.4 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 OAP63727.1 - 4.6e-06 26.2 0.1 8.2e-06 25.4 0.1 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 OAP63727.1 - 0.083 12.2 0.1 0.16 11.2 0.1 1.5 1 1 0 1 1 1 0 Beta-eliminating lyase EMP24_GP25L PF01105.24 OAP63728.1 - 0.018 15.0 0.2 0.018 15.0 0.2 2.0 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD TACC_C PF05010.14 OAP63728.1 - 0.038 13.8 1.9 0.075 12.8 0.5 1.9 2 0 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF2207 PF09972.9 OAP63728.1 - 0.1 11.4 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4337 PF14235.6 OAP63728.1 - 0.12 12.4 1.1 0.17 12.0 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) Synaptobrevin PF00957.21 OAP63728.1 - 0.16 11.7 0.4 0.53 10.1 0.4 1.9 1 0 0 1 1 1 0 Synaptobrevin SHE3 PF17078.5 OAP63728.1 - 0.18 11.5 1.2 0.28 10.9 0.6 1.5 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 BBP1_C PF15272.6 OAP63728.1 - 0.18 11.6 1.0 0.28 11.0 1.0 1.2 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal DUF3552 PF12072.8 OAP63728.1 - 0.21 11.0 0.0 0.21 11.0 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF3552) DotU PF09850.9 OAP63728.1 - 0.23 11.2 2.7 0.24 11.1 0.3 2.2 2 0 0 2 2 2 0 Type VI secretion system protein DotU V_ATPase_I PF01496.19 OAP63728.1 - 0.23 9.3 0.2 0.31 8.9 0.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA_13 PF13166.6 OAP63728.1 - 0.39 9.3 1.7 0.51 8.9 1.7 1.1 1 0 0 1 1 1 0 AAA domain Fez1 PF06818.15 OAP63728.1 - 0.53 10.7 7.5 0.83 10.1 7.5 1.2 1 0 0 1 1 1 0 Fez1 DUF4686 PF15742.5 OAP63728.1 - 0.64 9.1 7.3 2 7.5 7.3 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4686) VIT1 PF01988.19 OAP63728.1 - 0.8 9.5 3.6 4.2 7.2 4.3 1.8 1 1 1 2 2 2 0 VIT family ZapB PF06005.12 OAP63728.1 - 0.85 10.1 6.9 22 5.6 3.8 2.6 2 0 0 2 2 2 0 Cell division protein ZapB PBP_N PF17093.5 OAP63728.1 - 3.2 8.0 6.4 2.5 8.4 1.0 2.2 2 0 0 2 2 2 0 Penicillin-binding protein N-terminus Nup54 PF13874.6 OAP63728.1 - 7.5 6.7 9.7 7.2 6.7 0.3 2.4 1 1 0 2 2 2 0 Nucleoporin complex subunit 54 Tubulin PF00091.25 OAP63729.1 - 4.3e-65 219.6 0.0 5.9e-65 219.2 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 OAP63729.1 - 4.9e-45 152.8 0.0 7.9e-45 152.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 OAP63729.1 - 0.00066 19.4 0.0 0.0012 18.6 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain MS_channel PF00924.18 OAP63730.1 - 1.9e-23 83.1 0.9 2.9e-23 82.5 0.9 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_5 PF13202.6 OAP63730.1 - 5.7e-05 22.4 0.0 0.00015 21.1 0.0 1.8 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 OAP63730.1 - 0.00024 20.8 0.1 0.0035 17.2 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 OAP63730.1 - 0.00039 19.8 0.3 0.0012 18.2 0.3 1.9 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 OAP63730.1 - 0.0065 16.9 0.2 0.022 15.2 0.2 1.9 1 0 0 1 1 1 1 EF-hand domain pair DUF5137 PF17220.3 OAP63730.1 - 0.026 15.4 0.4 0.21 12.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF5137) Phage_1_1 PF08200.11 OAP63730.1 - 0.027 14.9 1.4 0.071 13.5 1.4 1.7 1 0 0 1 1 1 0 Bacteriophage 1.1 Protein adh_short PF00106.25 OAP63731.1 - 5.1e-30 104.4 3.1 6.5e-30 104.0 3.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP63731.1 - 7.4e-16 58.4 1.0 9.4e-16 58.1 1.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP63731.1 - 6e-11 42.6 0.3 7.8e-11 42.2 0.3 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAP63731.1 - 5.7e-08 32.5 0.2 8.5e-08 32.0 0.2 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 OAP63731.1 - 1.9e-07 30.5 1.0 2.4e-07 30.2 1.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 OAP63731.1 - 0.00018 21.1 0.2 0.00031 20.3 0.2 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 2-Hacid_dh_C PF02826.19 OAP63731.1 - 0.00024 20.5 0.1 0.069 12.5 0.0 2.2 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 OAP63731.1 - 0.0021 17.7 0.1 0.0034 17.0 0.1 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA SBP_bac_1 PF01547.25 OAP63731.1 - 0.0029 17.6 0.5 0.014 15.4 0.2 2.0 1 1 1 2 2 2 1 Bacterial extracellular solute-binding protein F420_oxidored PF03807.17 OAP63731.1 - 0.0037 17.8 0.7 0.0081 16.7 0.7 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 OAP63731.1 - 0.0044 17.3 0.3 0.0092 16.2 0.3 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 OAP63731.1 - 0.0065 16.5 0.0 0.01 15.9 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Glyco_tran_WecB PF03808.13 OAP63731.1 - 0.014 15.3 0.1 0.042 13.8 0.0 1.7 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family Rossmann-like PF10727.9 OAP63731.1 - 0.026 14.4 0.2 0.064 13.1 0.2 1.6 1 0 0 1 1 1 0 Rossmann-like domain 3HCDH_N PF02737.18 OAP63731.1 - 0.027 14.4 0.3 0.051 13.5 0.3 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.17 OAP63731.1 - 0.045 12.8 0.2 0.079 12.0 0.2 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain DapB_N PF01113.20 OAP63731.1 - 0.095 12.8 0.5 0.23 11.6 0.5 1.6 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus ThiF PF00899.21 OAP63731.1 - 1.4 8.2 6.1 0.87 8.9 2.6 2.1 1 1 1 2 2 2 0 ThiF family PRC PF05239.16 OAP63732.1 - 0.019 15.1 1.1 0.49 10.5 0.0 2.8 3 0 0 3 3 3 0 PRC-barrel domain Myosin_head PF00063.21 OAP63733.1 - 2e-239 796.4 4.4 2.3e-239 796.1 4.4 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 OAP63733.1 - 8.7e-49 165.7 0.0 1.7e-48 164.8 0.0 1.5 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding SH3_1 PF00018.28 OAP63733.1 - 8.1e-13 47.8 0.1 1.9e-12 46.5 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 OAP63733.1 - 2e-10 40.3 0.0 5.6e-10 38.9 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 OAP63733.1 - 3e-10 39.6 0.0 9.1e-10 38.1 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain AAA_22 PF13401.6 OAP63733.1 - 0.018 15.3 0.0 0.051 13.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain Hpr_kinase_C PF07475.12 OAP63733.1 - 0.02 14.4 0.6 3 7.3 0.0 2.6 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain IQ PF00612.27 OAP63733.1 - 0.024 14.4 8.3 1.4 9.0 1.0 2.8 1 1 1 2 2 2 0 IQ calmodulin-binding motif AAA_16 PF13191.6 OAP63733.1 - 0.033 14.6 0.0 0.08 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain SdrD_B PF17210.3 OAP63733.1 - 0.073 13.3 0.7 0.22 11.8 0.1 2.0 2 0 0 2 2 2 0 SdrD B-like domain hSH3 PF14603.6 OAP63733.1 - 0.11 12.9 0.0 0.32 11.4 0.0 1.8 1 0 0 1 1 1 0 Helically-extended SH3 domain SH3_3 PF08239.11 OAP63733.1 - 0.17 12.2 0.2 0.44 10.9 0.2 1.7 1 0 0 1 1 1 0 Bacterial SH3 domain NACHT PF05729.12 OAP63733.1 - 0.19 11.6 0.1 0.51 10.2 0.1 1.7 2 0 0 2 2 2 0 NACHT domain HNH_2 PF13391.6 OAP63734.1 - 7.2e-15 54.9 0.0 1.3e-14 54.0 0.0 1.5 1 0 0 1 1 1 1 HNH endonuclease Mst1_SARAH PF11629.8 OAP63735.1 - 0.055 13.6 0.0 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 C terminal SARAH domain of Mst1 OPA3 PF07047.12 OAP63736.1 - 6.9e-47 158.3 2.6 6.9e-47 158.3 2.6 1.7 2 0 0 2 2 2 1 Optic atrophy 3 protein (OPA3) Med11 PF10280.9 OAP63736.1 - 0.21 12.0 9.6 0.028 14.9 3.4 2.7 1 1 1 2 2 2 0 Mediator complex protein Pkinase PF00069.25 OAP63737.1 - 6.3e-71 238.8 0.1 8.7e-71 238.4 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP63737.1 - 3.1e-45 154.5 0.2 4.7e-45 153.9 0.2 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAP63737.1 - 2.2e-07 30.5 0.0 0.00023 20.6 0.0 2.2 2 0 0 2 2 2 2 Kinase-like POLO_box PF00659.18 OAP63737.1 - 2.5e-06 27.6 0.0 0.082 13.1 0.0 2.6 2 0 0 2 2 2 2 POLO box duplicated region Haspin_kinase PF12330.8 OAP63737.1 - 0.042 12.8 0.1 0.066 12.1 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 OAP63737.1 - 0.043 13.2 0.0 0.099 12.0 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family 2-Hacid_dh_C PF02826.19 OAP63738.1 - 1.8e-33 115.4 0.5 1.8e-20 73.0 0.0 3.7 3 1 0 3 3 3 3 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_4 PF01565.23 OAP63739.1 - 3.5e-08 33.3 0.1 0.00039 20.2 0.1 2.3 2 0 0 2 2 2 2 FAD binding domain ALO PF04030.14 OAP63739.1 - 8.9e-05 22.4 3.7 0.0011 18.8 0.4 2.2 2 0 0 2 2 2 2 D-arabinono-1,4-lactone oxidase VbhA PF18495.1 OAP63739.1 - 0.081 12.8 0.1 0.22 11.4 0.1 1.8 1 0 0 1 1 1 0 Antitoxin VbhA Chol_subst-bind PF09129.11 OAP63739.1 - 3.8 6.4 8.0 0.52 9.2 0.5 2.7 2 1 0 2 2 2 0 Cholesterol oxidase, substrate-binding DHDPS PF00701.22 OAP63740.1 - 5.8e-34 117.1 0.0 7e-34 116.9 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family DHHC PF01529.20 OAP63741.1 - 3e-14 53.2 3.1 4.1e-14 52.8 3.1 1.2 1 0 0 1 1 1 1 DHHC palmitoyltransferase DNA_mis_repair PF01119.19 OAP63742.1 - 3.5e-14 52.5 0.0 7.8e-14 51.4 0.0 1.6 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 OAP63742.1 - 1.3e-09 38.0 0.2 3.5e-09 36.6 0.2 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 OAP63742.1 - 4.7e-08 33.5 0.1 1.1e-07 32.3 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ACT_3 PF10000.9 OAP63743.1 - 1.9e-12 46.9 0.2 5.3e-10 39.1 0.0 2.4 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.6 OAP63743.1 - 3.6e-10 39.5 0.0 5.6e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 ACT domain Herpes_DNAp_acc PF04929.12 OAP63744.1 - 0.064 12.2 0.0 0.077 12.0 0.0 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Pkinase PF00069.25 OAP63746.1 - 3.1e-29 102.2 0.0 2.9e-28 99.0 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP63746.1 - 7.3e-20 71.3 0.0 1.1e-19 70.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAP63746.1 - 0.0017 17.8 0.0 0.0027 17.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 OAP63746.1 - 0.048 13.6 0.1 0.091 12.7 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OAP63746.1 - 0.1 11.5 1.9 0.12 11.3 0.0 1.8 2 0 0 2 2 2 0 Haspin like kinase domain Patatin PF01734.22 OAP63747.1 - 5.3e-05 23.5 0.0 0.00011 22.4 0.0 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase HeLo PF14479.6 OAP63748.1 - 6.8e-23 81.6 0.0 1.1e-22 80.9 0.0 1.3 1 0 0 1 1 1 1 Prion-inhibition and propagation Pkinase_Tyr PF07714.17 OAP63748.1 - 0.056 12.7 0.0 0.27 10.5 0.0 2.0 1 1 0 1 1 1 0 Protein tyrosine kinase Transp_cyt_pur PF02133.15 OAP63750.1 - 1.9e-103 346.6 44.3 2.2e-103 346.4 44.3 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin CcmD PF04995.14 OAP63750.1 - 0.061 13.4 0.0 0.061 13.4 0.0 4.6 4 1 1 5 5 5 0 Heme exporter protein D (CcmD) DUF917 PF06032.12 OAP63751.1 - 6.7e-110 367.2 0.0 1.4e-109 366.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF917) Hydant_A_N PF05378.13 OAP63751.1 - 5.6e-28 97.8 4.1 2.1e-25 89.5 0.0 3.6 4 0 0 4 4 4 2 Hydantoinase/oxoprolinase N-terminal region Hydantoinase_A PF01968.18 OAP63751.1 - 5.2e-26 91.6 7.4 8.1e-23 81.1 0.4 3.3 2 1 1 3 3 3 2 Hydantoinase/oxoprolinase MutL PF13941.6 OAP63751.1 - 4.9e-06 25.4 1.7 0.011 14.4 0.0 2.3 2 0 0 2 2 2 2 MutL protein BcrAD_BadFG PF01869.20 OAP63751.1 - 0.0011 18.5 0.7 0.0034 16.9 0.1 2.2 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family PGM_PMM_I PF02878.16 OAP63751.1 - 0.0035 17.1 0.2 0.044 13.5 0.0 2.7 3 0 0 3 3 3 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I ROK PF00480.20 OAP63751.1 - 0.068 12.6 0.4 0.24 10.8 0.1 2.0 2 0 0 2 2 2 0 ROK family FtsA PF14450.6 OAP63751.1 - 0.13 12.7 7.0 1.6 9.2 0.4 3.8 4 0 0 4 4 4 0 Cell division protein FtsA DUF3453 PF11935.8 OAP63752.1 - 2.7e-70 236.5 0.9 5.5e-70 235.5 0.9 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3453) DUF615 PF04751.14 OAP63752.1 - 0.0049 16.9 0.1 9.8 6.1 0.0 3.5 3 0 0 3 3 3 2 Protein of unknown function (DUF615) MFS_1 PF07690.16 OAP63753.1 - 3.4e-39 134.8 48.2 3.4e-39 134.8 48.2 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 OAP63753.1 - 4.8e-10 38.5 13.7 8.6e-10 37.7 13.7 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) PAP_PilO PF06864.12 OAP63753.1 - 0.14 10.9 0.2 0.78 8.5 0.0 1.9 2 0 0 2 2 2 0 Pilin accessory protein (PilO) LapA_dom PF06305.11 OAP63753.1 - 3.3 7.6 0.0 3.3 7.6 0.0 5.0 4 2 1 5 5 5 0 Lipopolysaccharide assembly protein A domain Thiolase_N PF00108.23 OAP63755.1 - 7.7e-66 222.1 0.0 9.6e-66 221.8 0.0 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 OAP63755.1 - 3.5e-39 133.2 0.0 6.4e-39 132.4 0.0 1.4 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III PF08545.10 OAP63755.1 - 0.0053 16.6 0.1 0.68 9.8 0.0 2.4 2 0 0 2 2 2 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.26 OAP63755.1 - 0.064 12.8 1.8 0.18 11.3 0.5 2.1 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain PS_Dcarbxylase PF02666.15 OAP63756.1 - 1.7e-46 158.3 0.0 2.3e-46 157.9 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase WD40 PF00400.32 OAP63757.1 - 2e-31 107.5 20.6 1.6e-07 31.9 0.1 8.0 7 1 0 7 7 7 5 WD domain, G-beta repeat PRP4 PF08799.11 OAP63757.1 - 1.1e-13 50.4 3.8 1.1e-13 50.4 3.8 2.9 3 0 0 3 3 3 1 pre-mRNA processing factor 4 (PRP4) like ANAPC4_WD40 PF12894.7 OAP63757.1 - 9.3e-12 45.1 0.0 0.0036 17.6 0.0 5.6 4 1 2 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Nbas_N PF15492.6 OAP63757.1 - 0.049 13.0 0.0 13 5.0 0.0 3.1 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Fungal_trans PF04082.18 OAP63758.1 - 7.2e-07 28.5 0.0 1.3e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP63758.1 - 0.00019 21.5 7.8 0.00049 20.2 7.8 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1772 PF08592.11 OAP63760.1 - 6.1e-13 49.3 0.9 6.8e-13 49.1 0.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) DUF308 PF03729.13 OAP63760.1 - 0.16 12.3 2.7 4.8 7.6 0.1 2.2 2 0 0 2 2 2 0 Short repeat of unknown function (DUF308) MFS_1 PF07690.16 OAP63761.1 - 7.2e-16 58.0 52.4 1.2e-10 40.9 16.1 3.3 1 1 2 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.13 OAP63761.1 - 3.4e-12 45.6 24.9 2.5e-11 42.7 23.6 2.0 1 1 1 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Peptidase_S9 PF00326.21 OAP63762.1 - 7e-54 182.5 2.9 7e-54 182.5 2.9 1.5 2 0 0 2 2 2 1 Prolyl oligopeptidase family PD40 PF07676.12 OAP63762.1 - 0.00056 19.8 0.7 0.059 13.3 0.1 3.5 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat DUF218 PF02698.17 OAP63763.1 - 1.4e-06 28.4 0.0 2.1e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 DUF218 domain Sugar_tr PF00083.24 OAP63765.1 - 1e-83 281.7 28.0 1.2e-83 281.5 28.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP63765.1 - 2.2e-31 109.1 48.0 9.6e-22 77.4 22.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily IRK PF01007.20 OAP63765.1 - 0.031 14.1 1.1 0.031 14.1 1.1 2.2 2 0 0 2 2 2 0 Inward rectifier potassium channel transmembrane domain Fungal_trans PF04082.18 OAP63766.1 - 2e-26 92.6 0.7 3.6e-26 91.8 0.7 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP63766.1 - 1.8e-07 31.2 8.7 3.3e-07 30.3 8.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acyl_transf_3 PF01757.22 OAP63767.1 - 1.1e-18 67.4 27.9 1.5e-18 67.0 27.9 1.2 1 0 0 1 1 1 1 Acyltransferase family ubiquitin PF00240.23 OAP63769.1 - 5.4e-102 333.6 13.3 1.9e-33 114.0 0.6 3.0 3 0 0 3 3 3 3 Ubiquitin family Rad60-SLD PF11976.8 OAP63769.1 - 1.3e-48 162.7 13.8 1.2e-15 57.1 0.7 3.0 3 0 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 OAP63769.1 - 7.5e-18 64.8 6.1 0.00026 21.4 0.1 4.6 3 3 0 3 3 3 3 Ubiquitin-like domain Ubiquitin_5 PF18037.1 OAP63769.1 - 1.6e-12 47.6 2.3 0.014 15.7 0.1 3.1 1 1 2 3 3 3 3 Ubiquitin-like domain TBK1_ULD PF18396.1 OAP63769.1 - 1.7e-12 47.1 1.7 0.016 15.1 0.1 3.2 3 0 0 3 3 3 3 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 OAP63769.1 - 4.7e-11 42.8 1.3 0.073 13.2 0.0 3.9 3 3 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 OAP63769.1 - 7.2e-10 39.4 0.3 0.21 12.1 0.0 3.2 1 1 1 3 3 3 3 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 OAP63769.1 - 1.7e-08 34.4 0.3 0.3 10.9 0.0 3.1 1 1 2 3 3 3 3 Silencing defective 2 N-terminal ubiquitin domain Ubiquitin_4 PF18036.1 OAP63769.1 - 2.4e-06 27.5 16.0 11 6.1 0.2 6.0 6 0 0 6 6 6 0 Ubiquitin-like domain DUF3861 PF12977.7 OAP63769.1 - 8.5e-05 22.7 1.0 8 6.7 0.0 3.2 3 0 0 3 3 3 0 Domain of Unknown Function with PDB structure (DUF3861) ACT_5 PF13710.6 OAP63769.1 - 0.00015 21.5 2.1 6.9 6.6 0.0 3.3 3 0 0 3 3 3 0 ACT domain DUF2870 PF11069.8 OAP63769.1 - 0.00027 21.2 0.0 20 5.6 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2870) Methyltrans_RNA PF04452.14 OAP63769.1 - 0.00058 19.3 0.1 1.1 8.5 0.0 2.4 2 0 0 2 2 2 2 RNA methyltransferase Big_7 PF17957.1 OAP63769.1 - 0.0011 19.6 0.1 34 5.3 0.0 3.2 3 0 0 3 3 3 0 Bacterial Ig domain YcgR_2 PF12945.7 OAP63769.1 - 0.003 17.7 2.9 19 5.5 0.1 3.3 3 0 0 3 3 3 0 Flagellar protein YcgR UDP-g_GGTase PF06427.11 OAP63769.1 - 0.0069 16.5 3.0 4.5 7.4 0.0 3.1 4 0 0 4 4 3 2 UDP-glucose:Glycoprotein Glucosyltransferase DUF969 PF06149.12 OAP63769.1 - 0.0076 15.7 0.0 15 5.0 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF969) DUF493 PF04359.14 OAP63769.1 - 0.031 14.9 0.0 95 3.7 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF493) Raf1_HTH PF18579.1 OAP63769.1 - 0.031 14.0 0.0 71 3.2 0.0 3.2 3 0 0 3 3 3 0 Rubisco accumulation factor 1 helix turn helix domain ACT_4 PF13291.6 OAP63769.1 - 0.032 14.8 0.3 96 3.7 0.0 3.3 3 0 0 3 3 3 0 ACT domain ORF11CD3 PF10549.9 OAP63769.1 - 0.088 12.9 0.0 62 3.8 0.0 3.4 3 0 0 3 3 3 0 ORF11CD3 domain ProRS-C_2 PF09181.10 OAP63769.1 - 0.12 12.5 2.6 72 3.6 0.1 3.2 3 0 0 3 3 3 0 Prolyl-tRNA synthetase, C-terminal Tash_PEST PF07708.11 OAP63769.1 - 0.13 12.4 18.4 4.5 7.6 1.4 3.3 3 0 0 3 3 3 0 Tash protein PEST motif Myosin_N PF02736.19 OAP63769.1 - 0.27 11.1 3.4 76 3.3 0.0 4.3 3 0 0 3 3 3 0 Myosin N-terminal SH3-like domain DMA PF03474.14 OAP63769.1 - 0.44 10.2 1.7 1.1e+02 2.5 0.0 3.2 3 0 0 3 3 3 0 DMRTA motif Plexin_cytopl PF08337.12 OAP63769.1 - 0.53 8.9 10.5 8.3 4.9 0.4 3.9 2 1 1 4 4 4 0 Plexin cytoplasmic RasGAP domain PI3K_p85B PF02192.16 OAP63769.1 - 0.85 9.4 5.0 67 3.3 0.1 3.3 3 0 0 3 3 3 0 PI3-kinase family, p85-binding domain FlgD_ig PF13860.6 OAP63769.1 - 2.8 7.9 4.9 1.2e+02 2.6 0.1 3.3 3 0 0 3 3 3 0 FlgD Ig-like domain Cu_amine_oxid PF01179.20 OAP63770.1 - 4.9e-07 29.0 1.2 0.0063 15.5 0.6 4.0 2 1 0 2 2 2 2 Copper amine oxidase, enzyme domain Cupin_2 PF07883.11 OAP63771.1 - 7.5e-15 54.4 0.1 5.7e-08 32.4 0.1 2.7 2 1 0 2 2 2 2 Cupin domain Cupin_1 PF00190.22 OAP63771.1 - 9e-05 22.1 0.0 0.16 11.6 0.0 2.3 2 0 0 2 2 2 2 Cupin MannoseP_isomer PF01050.18 OAP63771.1 - 0.00036 20.4 0.0 0.0015 18.4 0.0 1.8 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase Cupin_3 PF05899.12 OAP63771.1 - 0.0055 16.4 0.0 0.75 9.5 0.0 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF861) FdtA PF05523.11 OAP63771.1 - 0.12 12.1 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 WxcM-like, C-terminal TPR_10 PF13374.6 OAP63772.1 - 4.3e-97 315.7 16.1 2.2e-13 49.6 0.0 11.9 12 0 0 12 12 12 9 Tetratricopeptide repeat TPR_12 PF13424.6 OAP63772.1 - 1.1e-87 288.3 26.7 4.1e-16 59.0 0.5 8.6 3 3 6 9 9 9 9 Tetratricopeptide repeat TPR_7 PF13176.6 OAP63772.1 - 6.1e-27 91.7 18.7 0.0055 16.6 0.0 10.1 10 0 0 10 10 9 7 Tetratricopeptide repeat TPR_2 PF07719.17 OAP63772.1 - 1.8e-21 74.5 8.4 0.015 15.3 0.0 10.4 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_1 PF00515.28 OAP63772.1 - 1.3e-19 69.1 3.9 0.1 12.4 0.0 9.4 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_16 PF13432.6 OAP63772.1 - 1.5e-16 60.8 9.1 0.0037 17.9 0.0 8.9 6 4 2 8 8 8 4 Tetratricopeptide repeat TPR_4 PF07721.14 OAP63772.1 - 3.1e-16 58.3 11.9 0.031 14.9 0.0 10.2 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_19 PF14559.6 OAP63772.1 - 1.3e-13 51.3 8.8 0.012 16.1 0.5 8.2 5 2 5 10 10 10 4 Tetratricopeptide repeat TPR_MalT PF17874.1 OAP63772.1 - 6.3e-12 45.5 18.4 7e-07 28.9 5.3 3.0 1 1 0 2 2 2 2 MalT-like TPR region TPR_8 PF13181.6 OAP63772.1 - 1.1e-11 44.0 6.8 2.3 8.6 0.0 9.6 10 0 0 10 10 10 2 Tetratricopeptide repeat ANAPC3 PF12895.7 OAP63772.1 - 4.7e-10 39.6 1.3 0.4 10.9 0.0 7.5 2 2 5 7 7 7 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 OAP63772.1 - 3.4e-07 30.5 20.6 0.073 13.9 0.1 9.4 11 1 1 12 12 8 2 Tetratricopeptide repeat TPR_17 PF13431.6 OAP63772.1 - 1.2e-06 28.4 1.5 5.6 7.6 0.0 6.6 7 0 0 7 7 6 1 Tetratricopeptide repeat NB-ARC PF00931.22 OAP63772.1 - 1.7e-05 24.1 0.0 0.00014 21.2 0.0 2.3 1 1 0 1 1 1 1 NB-ARC domain PNP_UDP_1 PF01048.20 OAP63772.1 - 1.8e-05 24.1 1.1 0.00032 20.0 1.1 2.4 1 1 0 1 1 1 1 Phosphorylase superfamily TPR_6 PF13174.6 OAP63772.1 - 0.00038 20.9 14.7 18 6.3 0.2 8.8 9 0 0 9 9 8 0 Tetratricopeptide repeat NACHT PF05729.12 OAP63772.1 - 0.002 18.1 0.0 0.025 14.5 0.0 2.7 2 1 1 3 3 3 1 NACHT domain Fis1_TPR_C PF14853.6 OAP63772.1 - 0.052 13.6 0.2 69 3.6 0.0 4.5 6 0 0 6 6 5 0 Fis1 C-terminal tetratricopeptide repeat AAA_25 PF13481.6 OAP63772.1 - 0.09 12.3 0.0 0.23 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain TPR_20 PF14561.6 OAP63772.1 - 0.097 13.0 11.5 28 5.1 0.1 6.8 5 2 4 9 9 8 0 Tetratricopeptide repeat BRAP2 PF07576.12 OAP63773.1 - 2.7e-33 114.1 0.0 6.3e-33 113.0 0.0 1.5 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.19 OAP63773.1 - 4.7e-19 68.5 3.6 1.3e-18 67.0 3.6 1.8 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.6 OAP63773.1 - 6e-09 36.1 8.7 6e-09 36.1 8.7 2.6 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 OAP63773.1 - 3.1e-06 26.9 8.7 3.1e-06 26.9 8.7 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OAP63773.1 - 1.2e-05 24.9 4.8 1.2e-05 24.9 4.8 2.4 2 0 0 2 2 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 OAP63773.1 - 1.9e-05 24.4 7.2 5e-05 23.1 7.2 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OAP63773.1 - 5.7e-05 22.9 5.0 5.7e-05 22.9 5.0 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OAP63773.1 - 0.00015 21.9 6.0 0.00054 20.2 6.0 2.0 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 OAP63773.1 - 0.00037 20.4 6.5 0.00037 20.4 6.5 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 OAP63773.1 - 0.00037 20.5 9.4 0.00045 20.2 7.0 2.5 2 1 1 3 3 2 1 RING-type zinc-finger DUF892 PF05974.12 OAP63773.1 - 0.0057 16.7 8.3 0.012 15.6 8.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF892) zf-ANAPC11 PF12861.7 OAP63773.1 - 0.0095 16.0 5.0 0.022 14.8 5.0 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.6 OAP63773.1 - 0.036 13.9 4.0 0.093 12.6 4.0 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DUF1759 PF03564.15 OAP63773.1 - 0.093 12.7 3.7 0.2 11.6 3.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1759) zf-RING_4 PF14570.6 OAP63773.1 - 0.23 11.3 6.0 0.47 10.3 6.0 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Med9 PF07544.13 OAP63773.1 - 0.3 11.2 6.7 0.76 9.9 6.7 1.6 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 HTH_57 PF18679.1 OAP63773.1 - 0.45 10.9 2.4 0.92 9.9 2.4 1.5 1 0 0 1 1 1 0 ThcOx helix turn helix domain Prok-RING_4 PF14447.6 OAP63773.1 - 0.46 10.4 19.7 0.19 11.6 10.2 3.4 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 Exonuc_VII_L PF02601.15 OAP63773.1 - 0.58 9.7 10.0 1 8.9 10.0 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit NBD94 PF16830.5 OAP63773.1 - 1.7 9.1 9.2 2.4 8.6 4.4 2.7 2 1 0 2 2 2 0 Nucleotide-Binding Domain 94 of RH Prominin PF05478.11 OAP63773.1 - 9 4.1 7.7 13 3.6 7.7 1.2 1 0 0 1 1 1 0 Prominin Transp_cyt_pur PF02133.15 OAP63774.1 - 9.8e-94 314.6 36.3 1.1e-93 314.4 36.3 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DIOX_N PF14226.6 OAP63775.1 - 7.3e-27 94.5 0.0 1.2e-26 93.8 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OAP63775.1 - 1.8e-13 50.8 0.0 8.3e-13 48.7 0.0 2.0 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Fungal_trans PF04082.18 OAP63776.1 - 6.4e-21 74.6 1.5 1e-20 73.9 1.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF294_C PF10335.9 OAP63776.1 - 0.16 11.7 0.1 0.34 10.7 0.1 1.4 1 0 0 1 1 1 0 Putative nucleotidyltransferase substrate binding domain Methyltransf_11 PF08241.12 OAP63777.1 - 1.1e-16 61.2 0.0 1.8e-16 60.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAP63777.1 - 2.8e-16 59.8 0.0 6.1e-16 58.7 0.0 1.6 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAP63777.1 - 8.6e-14 52.0 0.0 1.5e-13 51.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAP63777.1 - 4e-13 50.0 0.0 6.1e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAP63777.1 - 5.4e-13 49.0 0.0 7.4e-13 48.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 OAP63777.1 - 6.8e-06 25.7 0.0 0.00012 21.6 0.0 2.1 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 OAP63777.1 - 0.00054 19.6 0.0 0.0012 18.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain NodS PF05401.11 OAP63777.1 - 0.026 14.1 0.0 0.046 13.3 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_32 PF13679.6 OAP63777.1 - 0.032 14.2 0.0 0.053 13.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DUF4735 PF15882.5 OAP63777.1 - 0.11 12.0 0.6 0.15 11.5 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4735) Fungal_trans PF04082.18 OAP63778.1 - 1.2e-13 50.8 0.2 2e-13 50.0 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.25 OAP63779.1 - 4.8e-23 81.6 0.0 8.9e-21 74.2 0.0 2.4 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAP63779.1 - 6.2e-18 65.2 0.0 5.3e-17 62.2 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase MFS_1 PF07690.16 OAP63780.1 - 3e-34 118.5 35.0 4.5e-34 117.9 35.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Zn_clus PF00172.18 OAP63781.1 - 2.5e-05 24.3 6.8 4.4e-05 23.5 6.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 3HCDH_N PF02737.18 OAP63782.1 - 3.3e-27 95.5 0.0 4.8e-27 95.0 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 OAP63782.1 - 8.7e-23 80.8 0.0 1.7e-22 79.8 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain ApbA PF02558.16 OAP63782.1 - 0.034 13.8 0.0 0.072 12.7 0.0 1.7 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_2 PF03446.15 OAP63782.1 - 0.11 12.6 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_7 PF13241.6 OAP63782.1 - 0.14 12.6 0.0 0.28 11.7 0.0 1.6 1 1 0 1 1 1 0 Putative NAD(P)-binding NAD_Gly3P_dh_N PF01210.23 OAP63782.1 - 0.18 11.8 0.0 0.31 11.0 0.0 1.4 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus E1-E2_ATPase PF00122.20 OAP63783.1 - 4.9e-37 127.2 16.3 1.4e-29 102.9 0.1 3.7 4 0 0 4 4 4 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 OAP63783.1 - 1.5e-31 109.5 0.8 1.5e-31 109.5 0.8 2.4 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 OAP63783.1 - 4.9e-19 68.2 0.0 1.4e-18 66.8 0.0 1.8 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 OAP63783.1 - 1.7e-17 64.4 0.5 2.1e-13 51.0 0.1 3.2 3 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 OAP63783.1 - 7.7e-16 57.5 0.0 2.1e-15 56.1 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 OAP63783.1 - 0.00011 22.1 1.6 0.0032 17.2 0.9 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 OAP63783.1 - 0.17 12.3 0.0 0.45 10.9 0.0 1.8 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF2935 PF11155.8 OAP63784.1 - 0.0043 17.4 0.3 0.57 10.5 0.0 3.0 2 2 0 2 2 2 1 Domain of unknown function (DUF2935) UPF0449 PF15136.6 OAP63784.1 - 0.018 15.5 4.7 0.039 14.4 0.2 3.2 2 1 1 3 3 3 0 Uncharacterised protein family UPF0449 Lipoprotein_2 PF00921.17 OAP63784.1 - 0.022 14.4 1.4 0.11 12.1 0.0 2.1 1 1 1 2 2 2 0 Borrelia lipoprotein YojJ PF10372.9 OAP63784.1 - 0.19 11.9 1.3 0.76 9.9 0.0 2.6 3 0 0 3 3 3 0 Bacterial membrane-spanning protein N-terminus PLC-beta_C PF08703.10 OAP63784.1 - 0.34 10.9 8.1 1.4 8.9 2.9 2.9 3 0 0 3 3 3 0 PLC-beta C terminal Vps51 PF08700.11 OAP63784.1 - 0.48 10.5 7.0 15 5.8 0.2 3.8 3 1 0 3 3 3 0 Vps51/Vps67 BLOC1_2 PF10046.9 OAP63784.1 - 1.1 9.6 5.4 3.8 7.9 0.1 4.1 3 1 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Allexi_40kDa PF05549.11 OAP63784.1 - 2 7.8 8.9 3.8 7.0 0.2 3.1 2 1 1 3 3 3 0 Allexivirus 40kDa protein Syntaxin-6_N PF09177.11 OAP63784.1 - 3 8.5 16.3 1.7 9.3 1.1 4.9 2 1 3 5 5 5 0 Syntaxin 6, N-terminal ALS2CR8 PF15299.6 OAP63784.1 - 3.4 7.5 5.9 5.3 6.9 4.0 2.3 2 1 0 2 2 2 0 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 DUF962 PF06127.11 OAP63785.1 - 2.7e-26 91.5 0.0 5e-26 90.6 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF962) Stevor PF17410.2 OAP63785.1 - 0.16 11.5 0.1 0.34 10.4 0.1 1.4 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Cytochrom_B561 PF03188.16 OAP63786.1 - 1.1e-13 51.6 4.6 1.1e-13 51.6 4.6 2.3 2 1 1 3 3 3 1 Eukaryotic cytochrome b561 DUF2427 PF10348.9 OAP63786.1 - 0.0035 17.1 2.0 0.0035 17.1 2.0 3.1 3 1 0 3 3 3 1 Domain of unknown function (DUF2427) DUF4079 PF13301.6 OAP63786.1 - 0.034 14.3 18.5 0.16 12.1 4.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4079) Glyco_hydro_68 PF02435.16 OAP63786.1 - 0.2 10.5 0.0 0.26 10.1 0.0 1.1 1 0 0 1 1 1 0 Levansucrase/Invertase DUF420 PF04238.12 OAP63786.1 - 2.4 8.5 16.0 0.044 14.1 7.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF420) Fig1 PF12351.8 OAP63786.1 - 2.8 7.8 11.6 0.21 11.5 0.3 2.8 3 0 0 3 3 3 0 Ca2+ regulator and membrane fusion protein Fig1 SLATT_3 PF18184.1 OAP63786.1 - 4.8 7.3 6.8 0.35 11.0 0.3 2.2 2 1 1 3 3 3 0 SMODS and SLOG-associating 2TM effector domain 3 TMEM100 PF16311.5 OAP63786.1 - 7.9 6.1 12.1 1.8 8.2 2.9 2.8 3 0 0 3 3 3 0 Transmembrane protein 100 PNTB PF02233.16 OAP63787.1 - 4e-175 583.2 24.5 4e-175 583.2 24.5 1.9 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.21 OAP63787.1 - 1.8e-74 249.6 0.1 5.5e-74 248.1 0.1 1.9 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 OAP63787.1 - 5.1e-44 149.9 0.0 1.1e-43 148.9 0.0 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain PNTB_4TM PF12769.7 OAP63787.1 - 9.7e-29 99.7 2.6 9.7e-29 99.7 2.6 5.0 3 2 2 6 6 6 1 4TM region of pyridine nucleotide transhydrogenase, mitoch 2-Hacid_dh_C PF02826.19 OAP63787.1 - 0.0002 20.8 0.1 1.3 8.4 0.1 3.4 2 1 1 3 3 3 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N PF00107.26 OAP63787.1 - 0.0033 17.4 0.1 0.016 15.2 0.1 2.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pyr_redox_2 PF07992.14 OAP63787.1 - 0.0044 16.3 0.1 0.011 15.0 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase TPP_enzyme_M PF00205.22 OAP63787.1 - 0.0089 15.8 0.4 0.078 12.7 0.4 2.6 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain NAD_binding_8 PF13450.6 OAP63787.1 - 0.32 11.3 2.7 0.72 10.1 0.6 2.9 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain Acetyltransf_3 PF13302.7 OAP63788.1 - 1.9e-18 67.5 0.0 2.4e-18 67.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAP63788.1 - 1.1e-07 32.1 0.0 1.5e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 OAP63788.1 - 0.0052 16.5 0.0 0.0078 15.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 OAP63788.1 - 0.21 11.1 0.0 0.29 10.7 0.0 1.1 1 0 0 1 1 1 0 GNAT acetyltransferase FAD_binding_3 PF01494.19 OAP63790.1 - 4.5e-37 128.1 0.0 2e-20 73.3 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DDE_3 PF13358.6 OAP63791.1 - 1e-11 44.8 0.4 4e-11 42.9 0.2 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease Fungal_trans PF04082.18 OAP63792.1 - 1.2e-12 47.5 0.6 2e-12 46.7 0.6 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zip PF02535.22 OAP63793.1 - 3.9e-59 200.6 0.0 4.4e-59 200.4 0.0 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter UNC-50 PF05216.13 OAP63793.1 - 0.019 14.6 0.5 0.6 9.6 1.2 2.2 2 0 0 2 2 2 0 UNC-50 family Aa_trans PF01490.18 OAP63794.1 - 4.5e-27 94.8 26.5 5.2e-27 94.6 26.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein RBP_receptor PF14752.6 OAP63794.1 - 0.0041 15.8 0.2 0.008 14.8 0.2 1.4 1 0 0 1 1 1 1 Retinol binding protein receptor DUF1129 PF06570.11 OAP63794.1 - 1.7 8.1 7.5 2.7 7.4 1.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1129) CBS PF00571.28 OAP63795.1 - 1.4e-07 31.9 0.0 0.0067 16.8 0.0 3.1 2 1 0 2 2 2 2 CBS domain Mito_carr PF00153.27 OAP63796.1 - 3.9e-45 151.7 8.2 6e-18 64.6 0.2 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3602 PF12223.8 OAP63796.1 - 5.6e-19 68.5 8.8 3.2e-18 66.1 4.4 2.7 2 1 1 3 3 3 2 Protein of unknown function (DUF3602) DUF3484 PF11983.8 OAP63796.1 - 0.023 15.8 0.5 0.08 14.1 0.0 2.1 2 0 0 2 2 2 0 Membrane-attachment and polymerisation-promoting switch DUF4203 PF13886.6 OAP63796.1 - 9.8 5.8 7.6 1.8 8.2 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4203) BAH PF01426.18 OAP63797.1 - 0.00011 22.0 0.0 0.00019 21.2 0.0 1.4 1 0 0 1 1 1 1 BAH domain PHD PF00628.29 OAP63797.1 - 0.002 18.0 2.5 0.0044 16.9 2.5 1.6 1 0 0 1 1 1 1 PHD-finger TF_Zn_Ribbon PF08271.12 OAP63797.1 - 1.7 8.2 4.7 0.68 9.5 1.4 2.0 2 0 0 2 2 2 0 TFIIB zinc-binding MFS_1 PF07690.16 OAP63798.1 - 1.7e-51 175.3 47.3 6.6e-49 166.7 49.4 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 OAP63798.1 - 1.2e-17 63.6 21.0 2.6e-17 62.5 21.0 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 OAP63798.1 - 3.4e-12 46.0 10.0 3.4e-12 46.0 10.0 4.2 2 1 0 4 4 4 2 Sugar (and other) transporter MFS_4 PF06779.14 OAP63798.1 - 3.2e-05 23.4 5.2 3.2e-05 23.4 5.2 2.8 3 0 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB zf-CCCH PF00642.24 OAP63799.1 - 1.1e-21 76.2 35.3 1.8e-07 30.9 0.9 5.2 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 OAP63799.1 - 7.5e-18 64.0 43.2 2.5e-06 27.3 2.6 5.3 5 0 0 5 5 5 5 Zinc finger domain Torus PF16131.5 OAP63799.1 - 8.6e-12 45.7 28.1 0.0001 22.9 1.2 5.3 1 1 4 5 5 5 5 Torus domain zf-CCCH_4 PF18044.1 OAP63799.1 - 4.8e-05 23.1 1.0 4.8e-05 23.1 1.0 5.2 5 0 0 5 5 5 2 CCCH-type zinc finger Ribosomal_60s PF00428.19 OAP63799.1 - 0.055 14.1 2.5 0.091 13.4 2.5 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein zf-CCCH_3 PF15663.5 OAP63799.1 - 0.17 12.1 23.0 0.38 11.0 5.5 4.1 2 1 2 4 4 4 0 Zinc-finger containing family Toxin_34 PF08396.10 OAP63799.1 - 0.8 10.5 13.2 0.87 10.4 8.9 2.7 2 1 0 2 2 2 0 Spider toxin omega agatoxin/Tx1 family Esterase PF00756.20 OAP63800.1 - 9.3e-50 169.6 0.0 1.4e-49 169.1 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Esterase_phd PF10503.9 OAP63800.1 - 9.7e-06 25.2 0.0 0.00081 18.9 0.0 2.2 2 0 0 2 2 2 1 Esterase PHB depolymerase Abhydrolase_2 PF02230.16 OAP63800.1 - 0.00041 20.2 0.0 0.00069 19.5 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 OAP63800.1 - 0.00054 19.3 0.0 0.0015 17.8 0.0 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 OAP63800.1 - 0.00066 19.2 0.1 0.0013 18.2 0.1 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family Chlorophyllase2 PF12740.7 OAP63800.1 - 0.0039 16.1 0.0 0.0099 14.8 0.0 1.6 1 1 1 2 2 2 1 Chlorophyllase enzyme PAF-AH_p_II PF03403.13 OAP63800.1 - 0.013 14.0 0.0 0.022 13.3 0.0 1.3 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II DUF676 PF05057.14 OAP63800.1 - 0.053 13.0 0.0 0.084 12.4 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Lipase_3 PF01764.25 OAP63800.1 - 0.086 12.7 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) AXE1 PF05448.12 OAP63800.1 - 0.095 11.4 0.0 0.17 10.5 0.0 1.4 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) MFS_1 PF07690.16 OAP63801.1 - 9.7e-33 113.5 30.8 9.7e-33 113.5 30.8 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAP63801.1 - 2.5e-07 29.9 1.4 2.5e-07 29.9 1.4 3.8 3 1 1 4 4 4 2 Sugar (and other) transporter TRI12 PF06609.13 OAP63801.1 - 7.1e-06 24.7 3.4 7.1e-06 24.7 3.4 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) LapA_dom PF06305.11 OAP63801.1 - 0.78 9.6 10.3 1.2 9.0 3.0 3.5 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain Xpo1 PF08389.12 OAP63802.1 - 2.7e-37 128.1 0.8 2.5e-36 125.0 0.0 3.0 3 1 1 4 4 4 1 Exportin 1-like protein Ribosomal_L29e PF01779.17 OAP63803.1 - 5.3e-14 52.3 11.7 2.9e-07 30.7 0.9 2.4 2 0 0 2 2 2 2 Ribosomal L29e protein family 7tm_2 PF00002.24 OAP63804.1 - 1.1e-06 28.2 11.8 1.5e-06 27.7 11.8 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.11 OAP63804.1 - 0.00043 19.5 2.9 0.00043 19.5 2.9 2.1 1 1 1 2 2 2 1 Slime mold cyclic AMP receptor DUF2277 PF10041.9 OAP63804.1 - 0.22 11.9 0.0 0.43 11.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2277) Sybindin PF04099.12 OAP63805.1 - 1.1e-24 87.0 0.0 1.5e-24 86.6 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 OAP63805.1 - 0.017 15.3 0.1 0.023 14.8 0.1 1.2 1 0 0 1 1 1 0 Sedlin, N-terminal conserved region Pkinase PF00069.25 OAP63806.1 - 3.9e-55 187.1 0.0 7e-49 166.6 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAP63806.1 - 2.9e-34 118.5 0.4 1.6e-32 112.9 0.0 2.4 3 0 0 3 3 3 1 Protein tyrosine kinase Kinase-like PF14531.6 OAP63806.1 - 4.6e-08 32.7 0.0 4.8e-07 29.4 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 OAP63806.1 - 0.0041 17.1 3.5 0.0047 16.9 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OAP63806.1 - 0.074 11.8 3.1 0.13 11.0 0.0 2.7 3 0 0 3 3 3 0 Fungal protein kinase ANAPC_CDC26 PF10471.9 OAP63806.1 - 0.17 12.7 2.1 1.2 10.0 2.1 2.5 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit CDC26 DUF3987 PF13148.6 OAP63806.1 - 1 8.3 11.3 0.36 9.8 8.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) SRI PF08236.11 OAP63807.1 - 1.1e-21 76.7 12.8 1.1e-21 76.7 12.8 2.5 2 0 0 2 2 2 1 SRI (Set2 Rpb1 interacting) domain SET PF00856.28 OAP63807.1 - 5.6e-17 62.6 0.1 5.6e-17 62.6 0.1 3.7 4 0 0 4 4 4 1 SET domain AWS PF17907.1 OAP63807.1 - 5.3e-09 36.0 13.6 5.3e-09 36.0 13.6 1.9 2 0 0 2 2 2 1 AWS domain Med26 PF08711.11 OAP63807.1 - 3.4e-05 23.8 0.4 3.4e-05 23.8 0.4 2.2 2 0 0 2 2 2 1 TFIIS helical bundle-like domain TpcC PF12642.7 OAP63807.1 - 0.0014 18.5 0.2 0.0032 17.3 0.2 1.5 1 0 0 1 1 1 1 Conjugative transposon protein TcpC WW PF00397.26 OAP63807.1 - 0.039 14.0 1.0 0.098 12.8 1.0 1.8 1 0 0 1 1 1 0 WW domain eIF-6 PF01912.18 OAP63808.1 - 1.8e-80 269.0 0.5 2.4e-80 268.6 0.5 1.2 1 0 0 1 1 1 1 eIF-6 family Lipase_3 PF01764.25 OAP63810.1 - 2.2e-18 66.5 0.0 7e-16 58.4 0.0 2.5 1 1 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 OAP63810.1 - 0.033 14.8 2.9 0.13 12.9 2.7 2.1 1 1 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAP63810.1 - 0.16 11.2 0.0 0.29 10.3 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Nucleo_P87 PF07267.11 OAP63810.1 - 3.5 6.4 3.7 6.7 5.4 3.7 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 TAP_C PF03943.13 OAP63811.1 - 2.9e-14 52.4 0.2 5.5e-14 51.5 0.2 1.5 1 0 0 1 1 1 1 TAP C-terminal domain LRR_4 PF12799.7 OAP63811.1 - 1.4e-05 25.3 5.8 0.00028 21.2 1.1 2.6 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OAP63811.1 - 0.00018 21.2 1.2 0.00042 20.0 1.2 1.7 1 0 0 1 1 1 1 Leucine rich repeat Vps53_N PF04100.12 OAP63812.1 - 1.5e-104 350.0 7.7 2.2e-104 349.4 7.7 1.2 1 0 0 1 1 1 1 Vps53-like, N-terminal DUF2451 PF10474.9 OAP63812.1 - 3.5e-07 30.2 0.0 1.1e-06 28.7 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) Vps54_N PF10475.9 OAP63812.1 - 2.8e-05 23.5 10.7 4.8e-05 22.8 10.7 1.3 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex Sigma70_ner PF04546.13 OAP63812.1 - 0.018 14.9 10.8 1.9 8.3 8.7 3.0 2 1 0 2 2 2 0 Sigma-70, non-essential region COG2 PF06148.11 OAP63812.1 - 0.044 13.9 6.7 0.041 14.0 4.9 2.0 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 NBD94 PF16830.5 OAP63812.1 - 0.093 13.1 3.5 0.31 11.5 3.5 1.8 1 0 0 1 1 1 0 Nucleotide-Binding Domain 94 of RH Zw10 PF06248.13 OAP63812.1 - 0.24 9.9 11.4 0.65 8.5 11.5 1.5 1 1 0 1 1 1 0 Centromere/kinetochore Zw10 FapA PF03961.13 OAP63812.1 - 0.25 9.9 3.9 0.39 9.3 3.9 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A CENP-F_leu_zip PF10473.9 OAP63812.1 - 2.2 8.3 15.1 1.6 8.7 12.3 2.1 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF5339 PF17274.2 OAP63812.1 - 7.9 7.4 8.4 3.4 8.6 3.2 2.7 1 1 1 2 2 2 0 Family of unknown function (DUF5339) adh_short PF00106.25 OAP63813.1 - 2.1e-29 102.4 0.0 3.4e-29 101.7 0.0 1.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP63813.1 - 2.9e-19 69.6 0.9 4.2e-10 39.6 0.5 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP63813.1 - 0.00013 22.0 1.3 0.00058 19.8 0.1 2.0 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 OAP63813.1 - 0.022 14.2 0.1 0.087 12.3 0.0 1.9 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Methyltransf_25 PF13649.6 OAP63813.1 - 0.099 13.4 0.1 0.18 12.5 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase domain COPIIcoated_ERV PF07970.12 OAP63814.1 - 1.6e-84 283.2 0.0 2.4e-84 282.6 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 OAP63814.1 - 1.1e-29 102.6 0.0 2.2e-29 101.6 0.0 1.5 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) HSP90 PF00183.18 OAP63815.1 - 5.6e-224 744.8 34.0 7e-224 744.5 34.0 1.0 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 OAP63815.1 - 6.2e-16 58.9 0.1 1.2e-15 58.0 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 OAP63815.1 - 1.3e-10 41.2 1.5 2.1e-10 40.5 0.1 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase LOH1CR12 PF10158.9 OAP63815.1 - 0.037 14.0 0.4 0.2 11.7 0.2 2.3 2 0 0 2 2 2 0 Tumour suppressor protein DUF1676 PF07898.13 OAP63815.1 - 1.1 9.3 5.1 0.65 10.0 0.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1676) HLH PF00010.26 OAP63816.1 - 6.1e-13 48.5 0.1 2.2e-12 46.8 0.1 2.0 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain TPR_11 PF13414.6 OAP63817.1 - 0.00037 20.1 0.7 0.1 12.3 0.1 3.1 2 0 0 2 2 2 2 TPR repeat TPR_17 PF13431.6 OAP63817.1 - 0.0016 18.7 0.4 3 8.4 0.0 3.5 2 0 0 2 2 2 2 Tetratricopeptide repeat Nro1 PF12753.7 OAP63817.1 - 0.0017 17.4 0.3 0.0051 15.8 0.2 1.7 1 1 0 1 1 1 1 Nuclear pore complex subunit Nro1 TPR_14 PF13428.6 OAP63817.1 - 0.16 12.9 2.7 2.6 9.1 0.0 4.4 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 OAP63817.1 - 2.3 8.8 0.0 2.3 8.8 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF5350 PF17299.2 OAP63818.1 - 0.061 13.8 0.0 0.19 12.2 0.0 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5350) zf-H2C2_5 PF13909.6 OAP63819.1 - 0.0011 18.6 4.8 0.0011 18.6 4.8 2.6 2 0 0 2 2 2 1 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 OAP63819.1 - 0.0078 16.6 2.2 0.0078 16.6 2.2 3.1 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-met PF12874.7 OAP63819.1 - 1.2 9.7 8.0 16 6.0 0.2 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 OAP63819.1 - 2.5 8.7 18.6 1.7 9.2 3.0 3.6 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 OAP63819.1 - 5.8 8.0 19.4 0.41 11.6 1.8 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger Peptidase_M22 PF00814.25 OAP63820.1 - 3e-49 168.1 0.0 5.4e-48 164.0 0.0 2.6 1 1 0 1 1 1 1 Glycoprotease family Cornifin PF02389.15 OAP63821.1 - 2.4e-05 24.6 6.9 2.9e-05 24.3 6.9 1.1 1 0 0 1 1 1 1 Cornifin (SPRR) family AA_permease_2 PF13520.6 OAP63822.1 - 1.6e-53 182.0 47.0 2.1e-53 181.7 47.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAP63822.1 - 2.4e-19 69.3 39.4 3.5e-19 68.8 39.4 1.1 1 0 0 1 1 1 1 Amino acid permease PufQ PF05398.11 OAP63822.1 - 0.026 14.7 0.7 0.11 12.7 0.1 2.4 2 1 1 3 3 3 0 PufQ cytochrome subunit Neurensin PF14927.6 OAP63822.1 - 0.21 11.3 2.7 0.47 10.1 0.2 2.7 3 0 0 3 3 3 0 Neurensin DUF1254 PF06863.12 OAP63823.1 - 7.6e-29 100.5 3.0 1.3e-28 99.7 0.5 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1254) DUF1214 PF06742.11 OAP63823.1 - 1.4e-23 83.4 0.3 3.9e-23 82.0 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1214) DUF4449 PF14613.6 OAP63824.1 - 1.1e-06 28.9 0.3 1.1e-06 28.9 0.3 3.8 2 2 1 3 3 3 1 Protein of unknown function (DUF4449) Malic_M PF03949.15 OAP63825.1 - 6.1e-94 314.1 0.0 8.2e-94 313.7 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 OAP63825.1 - 2.3e-63 213.3 0.0 3.7e-63 212.6 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Mob1_phocein PF03637.17 OAP63826.1 - 6.2e-74 247.6 0.0 8.6e-74 247.1 0.0 1.1 1 0 0 1 1 1 1 Mob1/phocein family TFIIA PF03153.13 OAP63827.1 - 0.2 11.6 9.3 0.39 10.7 9.4 1.4 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Trypan_PARP PF05887.11 OAP63827.1 - 7.4 6.6 9.3 12 5.9 0.9 2.4 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Methyltransf_2 PF00891.18 OAP63828.1 - 8.1e-14 51.4 0.0 1.5e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_23 PF13489.6 OAP63829.1 - 6.2e-19 68.4 0.0 1.2e-18 67.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAP63829.1 - 1e-11 45.4 0.0 2.3e-11 44.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAP63829.1 - 9.4e-10 39.0 0.0 1.9e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAP63829.1 - 2.6e-09 37.0 0.0 8.5e-08 32.1 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAP63829.1 - 1.5e-06 28.8 0.0 9e-06 26.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 OAP63829.1 - 0.00049 19.6 0.0 0.00062 19.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.18 OAP63829.1 - 0.028 13.7 0.0 0.044 13.1 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain CMAS PF02353.20 OAP63829.1 - 0.037 13.3 0.0 0.071 12.4 0.0 1.5 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase MTS PF05175.14 OAP63829.1 - 0.04 13.5 0.0 0.1 12.1 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase small domain Ribosomal_L31 PF01197.18 OAP63830.1 - 0.025 14.8 0.0 0.048 13.9 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L31 Vps5 PF09325.10 OAP63831.1 - 6.6e-87 291.0 1.0 6.6e-87 291.0 1.0 1.5 2 0 0 2 2 2 1 Vps5 C terminal like PX PF00787.24 OAP63831.1 - 4.3e-26 91.1 0.0 1e-25 89.9 0.0 1.7 1 0 0 1 1 1 1 PX domain BAR_3 PF16746.5 OAP63831.1 - 0.005 16.6 3.1 0.17 11.5 1.3 2.5 1 1 1 2 2 2 2 BAR domain of APPL family Lipase_GDSL PF00657.22 OAP63831.1 - 0.077 13.0 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase BAR_3_WASP_bdg PF10456.9 OAP63831.1 - 0.096 12.1 0.1 1 8.8 0.1 2.1 1 1 0 1 1 1 0 WASP-binding domain of Sorting nexin protein Presenilin PF01080.17 OAP63832.1 - 0.064 12.0 0.0 0.082 11.7 0.0 1.1 1 0 0 1 1 1 0 Presenilin ATP-synt_DE_N PF02823.16 OAP63834.1 - 1.1e-17 63.7 0.1 1.6e-17 63.2 0.1 1.2 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain HECT_2 PF09814.9 OAP63835.1 - 2.5e-79 266.9 0.0 1.1e-76 258.2 0.0 2.0 1 1 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding POLO_box PF00659.18 OAP63835.1 - 0.076 13.2 0.1 0.15 12.3 0.1 1.4 1 0 0 1 1 1 0 POLO box duplicated region PI-PLC-X PF00388.19 OAP63836.1 - 1.3e-59 199.9 0.0 1.9e-59 199.4 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 OAP63836.1 - 7.6e-41 139.1 0.0 1.5e-40 138.1 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain CAP PF00188.26 OAP63839.1 - 3.4e-05 24.7 1.5 0.00019 22.2 0.3 2.4 2 1 0 2 2 2 1 Cysteine-rich secretory protein family FAD_binding_2 PF00890.24 OAP63841.1 - 2.2e-124 415.8 2.8 2.8e-124 415.4 2.8 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 OAP63841.1 - 3.3e-45 153.2 1.0 5e-45 152.6 1.0 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 OAP63841.1 - 5.9e-06 25.7 0.1 0.00085 18.6 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OAP63841.1 - 3.6e-05 23.0 1.9 0.024 13.7 2.2 2.4 2 0 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.17 OAP63841.1 - 6.7e-05 22.2 0.3 0.032 13.5 0.1 2.3 2 0 0 2 2 2 2 Thi4 family FAD_binding_3 PF01494.19 OAP63841.1 - 0.0032 16.8 0.6 0.0068 15.7 0.1 1.8 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 OAP63841.1 - 0.041 13.5 1.9 0.12 11.9 1.9 2.0 1 1 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 OAP63841.1 - 0.16 10.6 1.4 0.37 9.5 0.3 2.1 3 0 0 3 3 3 0 HI0933-like protein AAA PF00004.29 OAP63842.1 - 6e-41 140.0 0.0 1.1e-40 139.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OAP63842.1 - 1.2e-06 28.2 0.1 3.5e-06 26.7 0.0 1.8 2 0 0 2 2 1 1 AAA+ lid domain AAA_22 PF13401.6 OAP63842.1 - 6.5e-05 23.2 0.0 0.0059 16.9 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 OAP63842.1 - 0.00011 22.2 0.0 0.00043 20.3 0.0 2.2 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 OAP63842.1 - 0.00014 22.0 0.0 0.00069 19.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 OAP63842.1 - 0.00043 20.7 0.1 0.012 16.1 0.0 2.4 1 1 0 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 OAP63842.1 - 0.0015 17.8 0.0 0.0025 17.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 OAP63842.1 - 0.008 15.9 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 OAP63842.1 - 0.016 15.4 0.1 0.063 13.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 OAP63842.1 - 0.027 14.0 0.0 0.087 12.3 0.0 1.8 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 OAP63842.1 - 0.047 13.9 0.0 0.094 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 OAP63842.1 - 0.052 13.9 0.0 0.16 12.4 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 OAP63842.1 - 0.068 12.9 0.1 0.24 11.1 0.0 2.1 2 1 0 2 2 2 0 AAA domain AAA_3 PF07726.11 OAP63842.1 - 0.088 12.7 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 OAP63842.1 - 0.09 12.5 0.8 0.5 10.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain Antigen_Bd37 PF11641.8 OAP63842.1 - 0.096 12.2 0.2 0.2 11.2 0.2 1.4 1 0 0 1 1 1 0 Glycosylphosphatidylinositol-anchored merozoite surface protein AAA_30 PF13604.6 OAP63842.1 - 0.097 12.4 0.2 0.59 9.8 0.0 2.3 3 0 0 3 3 3 0 AAA domain ATPase PF06745.13 OAP63842.1 - 0.098 12.0 0.0 4.9 6.4 0.0 2.4 2 0 0 2 2 2 0 KaiC DUF4168 PF13767.6 OAP63842.1 - 0.1 13.8 1.9 0.45 11.7 2.1 1.9 2 0 0 2 2 1 0 Domain of unknown function (DUF4168) Mg_chelatase PF01078.21 OAP63842.1 - 0.12 11.7 0.1 0.35 10.2 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 OAP63842.1 - 0.14 12.7 0.0 0.49 10.9 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_14 PF13173.6 OAP63842.1 - 0.14 12.1 0.0 0.33 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain Cpn60_TCP1 PF00118.24 OAP63843.1 - 4.6e-150 500.5 13.3 5.1e-150 500.3 13.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family p450 PF00067.22 OAP63844.1 - 5.7e-51 173.7 0.0 7.3e-51 173.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Linker_histone PF00538.19 OAP63845.1 - 2.9e-31 107.7 0.3 8.1e-31 106.2 0.3 1.8 1 0 0 1 1 1 1 linker histone H1 and H5 family Toxin_trans PF07952.12 OAP63845.1 - 0.0077 15.4 0.2 0.011 14.9 0.2 1.1 1 0 0 1 1 1 1 Clostridium neurotoxin, Translocation domain ARL2_Bind_BART PF11527.8 OAP63845.1 - 0.069 13.3 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 The ARF-like 2 binding protein BART XPG_I PF00867.18 OAP63846.1 - 7e-32 109.7 2.1 1e-31 109.1 0.0 2.2 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.17 OAP63846.1 - 6.4e-28 97.2 0.0 2.2e-27 95.5 0.0 2.0 1 0 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc PF01367.20 OAP63846.1 - 1.5e-05 25.5 1.3 6.9e-05 23.4 0.0 2.5 2 1 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold HXXSHH PF07586.11 OAP63846.1 - 0.23 11.0 5.8 0.53 9.8 5.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) Acyl-CoA_dh_N PF02771.16 OAP63847.1 - 1.3e-27 96.7 0.2 2.5e-27 95.7 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 OAP63847.1 - 7.9e-24 84.6 0.1 1.3e-23 83.9 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 OAP63847.1 - 9.9e-17 60.9 0.0 1.7e-16 60.2 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 OAP63847.1 - 5.8e-05 23.4 0.1 0.00011 22.5 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain UQ_con PF00179.26 OAP63848.1 - 1.3e-52 177.2 0.0 1.4e-52 177.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OAP63848.1 - 0.007 16.1 0.0 0.0087 15.8 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 OAP63848.1 - 0.041 14.2 0.0 0.059 13.7 0.0 1.2 1 0 0 1 1 1 0 RWD domain UEV PF05743.13 OAP63848.1 - 0.045 13.6 0.0 0.07 13.0 0.0 1.3 1 0 0 1 1 1 0 UEV domain NAD_binding_6 PF08030.12 OAP63849.1 - 1.2e-33 116.5 0.0 3.7e-33 114.9 0.0 1.8 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 OAP63849.1 - 5.4e-21 74.7 0.0 1.5e-20 73.3 0.0 1.8 1 1 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 OAP63849.1 - 8.8e-19 67.9 13.8 1.1e-18 67.5 10.2 2.2 1 1 1 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.21 OAP63849.1 - 0.04 14.5 0.0 0.21 12.3 0.0 2.2 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 OAP63849.1 - 0.094 13.1 0.0 0.22 11.9 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain RTA1 PF04479.13 OAP63850.1 - 1.5e-69 233.7 12.1 1.5e-69 233.7 12.1 1.9 1 1 1 2 2 2 2 RTA1 like protein LCCL PF03815.19 OAP63851.1 - 2.8e-21 75.4 0.0 5.2e-21 74.6 0.0 1.4 1 0 0 1 1 1 1 LCCL domain DsbB PF02600.16 OAP63851.1 - 0.0082 16.6 0.0 0.0082 16.6 0.0 2.6 3 0 0 3 3 3 1 Disulfide bond formation protein DsbB Nuc_sug_transp PF04142.15 OAP63852.1 - 7.6e-112 373.5 23.8 2.5e-110 368.5 23.8 2.0 1 1 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 OAP63852.1 - 7.4e-08 31.9 12.9 7.4e-08 31.9 12.9 1.9 2 0 0 2 2 2 1 UAA transporter family EamA PF00892.20 OAP63852.1 - 9.7e-08 32.3 28.8 0.00021 21.4 4.3 2.2 2 0 0 2 2 2 2 EamA-like transporter family PUNUT PF16913.5 OAP63852.1 - 0.00017 20.9 16.6 0.00044 19.6 16.6 1.7 1 1 0 1 1 1 1 Purine nucleobase transmembrane transport CRT-like PF08627.10 OAP63852.1 - 0.00021 20.4 3.0 0.00021 20.4 3.0 1.9 2 0 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like EmrE PF13536.6 OAP63852.1 - 0.0032 17.1 13.8 0.0074 15.9 13.4 1.7 1 1 1 2 2 2 1 Putative multidrug resistance efflux transporter TPT PF03151.16 OAP63852.1 - 0.16 11.3 15.1 0.52 9.6 15.1 1.8 1 1 0 1 1 1 0 Triose-phosphate Transporter family DUF202 PF02656.15 OAP63852.1 - 0.44 11.0 0.1 0.44 11.0 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF202) Fungal_trans_2 PF11951.8 OAP63853.1 - 8.7e-14 51.1 1.4 3e-13 49.4 1.4 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain XPB_DRD PF18458.1 OAP63853.1 - 0.0021 17.9 0.0 0.0058 16.5 0.0 1.7 1 0 0 1 1 1 1 Xeroderma pigmentosum group B helicase damage recognition domain OrsD PF12013.8 OAP63854.1 - 0.0051 17.2 3.2 0.27 11.7 0.1 2.6 3 0 0 3 3 3 2 Orsellinic acid/F9775 biosynthesis cluster protein D TF_Zn_Ribbon PF08271.12 OAP63854.1 - 0.011 15.2 0.4 2.7 7.6 0.0 2.7 2 0 0 2 2 2 0 TFIIB zinc-binding UPF0547 PF10571.9 OAP63854.1 - 0.29 11.2 5.6 5 7.3 0.1 3.1 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 zf-IS66 PF13005.7 OAP63854.1 - 0.84 10.1 5.1 9.2 6.8 0.0 3.4 3 0 0 3 3 3 0 zinc-finger binding domain of transposase IS66 adh_short_C2 PF13561.6 OAP63855.1 - 3.8e-39 134.6 0.0 6.2e-28 97.9 0.0 3.0 2 1 1 3 3 3 3 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP63855.1 - 8.3e-38 129.8 0.0 2.8e-28 98.7 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 OAP63855.1 - 3.5e-11 43.3 0.0 2.6e-05 24.2 0.0 2.2 2 0 0 2 2 2 2 KR domain Epimerase PF01370.21 OAP63855.1 - 0.008 15.7 0.0 0.48 9.8 0.0 2.4 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 OAP63855.1 - 0.019 14.3 0.0 0.027 13.8 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) TPR_12 PF13424.6 OAP63856.1 - 2.8e-116 380.0 61.5 1.5e-19 70.0 2.3 8.0 1 1 8 9 9 9 9 Tetratricopeptide repeat TPR_10 PF13374.6 OAP63856.1 - 1.8e-112 364.6 26.7 3.1e-13 49.1 0.1 10.5 10 0 0 10 10 10 10 Tetratricopeptide repeat TPR_7 PF13176.6 OAP63856.1 - 2.3e-47 155.6 17.9 0.00012 21.8 0.1 9.6 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_1 PF00515.28 OAP63856.1 - 6.6e-39 130.2 27.2 0.0036 17.1 0.1 9.5 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_4 PF07721.14 OAP63856.1 - 2.7e-30 101.8 0.0 0.59 10.9 0.0 9.9 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_8 PF13181.6 OAP63856.1 - 7.1e-26 88.2 29.2 0.068 13.4 0.1 9.7 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_2 PF07719.17 OAP63856.1 - 4.6e-24 82.6 27.5 0.1 12.8 0.1 9.5 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_MalT PF17874.1 OAP63856.1 - 1.7e-22 80.3 13.2 6.4e-10 38.9 0.9 3.7 1 1 2 3 3 3 3 MalT-like TPR region TPR_16 PF13432.6 OAP63856.1 - 4.6e-20 72.0 36.7 7.7e-05 23.3 2.8 8.3 5 3 0 6 6 6 6 Tetratricopeptide repeat TPR_14 PF13428.6 OAP63856.1 - 7.7e-16 57.4 15.1 0.39 11.7 0.0 9.4 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_17 PF13431.6 OAP63856.1 - 2.7e-15 55.5 23.2 0.81 10.2 0.1 9.7 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_3 PF07720.12 OAP63856.1 - 9.5e-11 41.5 14.9 0.32 11.0 0.0 8.1 9 0 0 9 9 9 4 Tetratricopeptide repeat ANAPC3 PF12895.7 OAP63856.1 - 4.2e-08 33.3 4.1 0.63 10.3 0.0 5.5 3 1 3 6 6 5 4 Anaphase-promoting complex, cyclosome, subunit 3 RPN7 PF10602.9 OAP63856.1 - 2.9e-06 27.1 4.3 11 5.7 0.0 5.4 1 1 4 5 5 5 0 26S proteasome subunit RPN7 TPR_19 PF14559.6 OAP63856.1 - 2.6e-05 24.6 32.5 0.55 10.8 0.3 6.6 3 2 4 7 7 7 6 Tetratricopeptide repeat RPN6_C_helix PF18503.1 OAP63856.1 - 0.0021 17.8 1.8 85 3.0 0.0 5.3 5 0 0 5 5 5 0 26S proteasome subunit RPN6 C-terminal helix domain PPR PF01535.20 OAP63856.1 - 0.031 14.5 9.5 65 4.1 0.0 6.9 7 0 0 7 7 7 0 PPR repeat DUF4919 PF16266.5 OAP63856.1 - 0.12 12.3 4.7 9.5 6.1 0.1 3.7 2 1 3 5 5 4 0 Domain of unknown function (DUF4919) RPN6_N PF18055.1 OAP63856.1 - 0.97 9.8 4.3 43 4.5 0.0 4.3 2 2 3 5 5 5 0 26S proteasome regulatory subunit RPN6 N-terminal domain Peptidase_S8 PF00082.22 OAP63857.1 - 1.2e-10 41.2 0.2 5.6e-10 39.0 0.2 1.9 1 1 0 1 1 1 1 Subtilase family DDE_3 PF13358.6 OAP63858.1 - 4.5e-08 33.0 0.1 6.9e-08 32.4 0.1 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease CSN8_PSD8_EIF3K PF10075.9 OAP63858.1 - 0.15 12.1 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 CSN8/PSMD8/EIF3K family AMP-binding PF00501.28 OAP63860.1 - 1.3e-79 267.8 0.0 1.7e-79 267.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAP63860.1 - 7.3e-15 55.7 0.1 1.4e-14 54.8 0.1 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain SMC_N PF02463.19 OAP63861.1 - 1.2e-22 80.4 0.0 9.7e-22 77.5 0.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 OAP63861.1 - 2.8e-19 70.4 0.0 2.8e-19 70.4 0.0 4.5 3 1 0 4 4 4 1 AAA domain AAA_15 PF13175.6 OAP63861.1 - 1e-06 28.8 0.0 4.4e-06 26.7 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 OAP63861.1 - 0.00055 19.6 0.0 0.0011 18.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 OAP63861.1 - 0.00086 19.2 0.0 0.029 14.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran PF00005.27 OAP63861.1 - 0.051 14.1 0.0 0.051 14.1 0.0 3.6 3 1 0 3 3 3 0 ABC transporter Sec20 PF03908.13 OAP63861.1 - 0.16 11.9 0.4 1.2 9.2 0.1 2.8 2 0 0 2 2 2 0 Sec20 NPV_P10 PF05531.12 OAP63861.1 - 0.2 12.2 10.7 15 6.1 0.1 5.7 5 2 0 5 5 5 0 Nucleopolyhedrovirus P10 protein HALZ PF02183.18 OAP63861.1 - 4.3 7.6 10.5 0.48 10.7 1.4 3.6 3 0 0 3 3 3 0 Homeobox associated leucine zipper DUF948 PF06103.11 OAP63861.1 - 6.9 7.0 9.8 4.7 7.5 0.1 4.4 4 1 0 4 4 4 0 Bacterial protein of unknown function (DUF948) RGS PF00615.19 OAP63862.1 - 0.00011 22.5 0.0 0.16 12.2 0.0 2.4 2 0 0 2 2 2 2 Regulator of G protein signaling domain Peptidase_M50B PF13398.6 OAP63862.1 - 0.054 13.1 3.3 0.1 12.2 3.3 1.4 1 0 0 1 1 1 0 Peptidase M50B-like ORMDL PF04061.14 OAP63863.1 - 6.4e-59 197.6 4.4 7.6e-59 197.4 4.4 1.1 1 0 0 1 1 1 1 ORMDL family DEAD PF00270.29 OAP63865.1 - 5.4e-18 65.4 0.0 1e-17 64.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 OAP63865.1 - 3.3e-11 43.5 0.0 7.5e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 OAP63865.1 - 3.8e-06 27.2 0.0 1.1e-05 25.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PhoH PF02562.16 OAP63865.1 - 0.042 13.3 0.0 0.089 12.2 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein zf-CCHC_4 PF14392.6 OAP63866.1 - 0.053 13.3 16.8 0.24 11.2 0.3 4.2 4 0 0 4 4 4 0 Zinc knuckle SDA1 PF05285.12 OAP63866.1 - 0.1 12.0 16.1 0.15 11.5 16.1 1.2 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 OAP63866.1 - 0.31 9.2 20.9 0.43 8.7 20.9 1.1 1 0 0 1 1 1 0 Nop14-like family zf-CCHC_6 PF15288.6 OAP63866.1 - 4.3 7.2 12.6 3.6 7.5 0.2 3.6 2 1 1 3 3 3 0 Zinc knuckle TRAP_alpha PF03896.16 OAP63866.1 - 6.9 5.8 10.8 11 5.1 10.8 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit PPP4R2 PF09184.11 OAP63866.1 - 7.2 6.1 18.3 13 5.2 18.3 1.4 1 0 0 1 1 1 0 PPP4R2 CDC45 PF02724.14 OAP63866.1 - 7.3 4.8 14.0 9.9 4.3 14.0 1.1 1 0 0 1 1 1 0 CDC45-like protein RPT PF13446.6 OAP63867.1 - 1.2e-43 146.8 0.5 3.9e-13 49.1 0.1 4.6 4 0 0 4 4 4 4 A repeated domain in UCH-protein UCH PF00443.29 OAP63867.1 - 7.7e-39 133.7 0.0 2.9e-38 131.8 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OAP63867.1 - 0.00016 21.4 0.3 0.0014 18.3 0.1 2.3 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase PUB PF09409.10 OAP63867.1 - 0.0058 16.5 0.0 0.016 15.1 0.0 1.7 1 0 0 1 1 1 1 PUB domain Tim17 PF02466.19 OAP63868.1 - 2.5e-05 24.6 7.7 7.4e-05 23.1 7.4 1.8 1 1 1 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family PH PF00169.29 OAP63869.1 - 7.9e-05 23.1 0.1 0.00017 22.1 0.1 1.6 1 0 0 1 1 1 1 PH domain Prominin PF05478.11 OAP63869.1 - 0.0037 15.3 0.4 0.0053 14.8 0.4 1.1 1 0 0 1 1 1 1 Prominin Hydrolase_4 PF12146.8 OAP63870.1 - 0.0061 15.9 0.1 0.081 12.2 0.1 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Macoilin PF09726.9 OAP63871.1 - 0.42 9.1 7.0 0.55 8.7 7.0 1.1 1 0 0 1 1 1 0 Macoilin family CorA PF01544.18 OAP63872.1 - 1.4e-11 44.3 2.2 5.8e-10 39.0 0.9 2.2 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein CENP-Q PF13094.6 OAP63873.1 - 3.1e-34 118.6 6.9 8e-34 117.3 6.9 1.7 1 1 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit AAA_23 PF13476.6 OAP63873.1 - 0.052 14.0 0.2 0.088 13.3 0.2 1.3 1 0 0 1 1 1 0 AAA domain SCIMP PF15050.6 OAP63873.1 - 0.11 13.0 0.1 0.24 11.9 0.1 1.5 1 0 0 1 1 1 0 SCIMP protein MFS_1 PF07690.16 OAP63874.1 - 5.8e-32 111.0 25.5 5.8e-32 111.0 25.5 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily MASE2 PF05230.11 OAP63874.1 - 0.38 10.9 7.2 0.3 11.2 0.4 3.2 3 0 0 3 3 3 0 MASE2 domain Saf_2TM PF18303.1 OAP63874.1 - 1.9 8.1 7.9 8.6 5.9 0.8 3.5 3 0 0 3 3 3 0 SAVED-fused 2TM effector domain Sugar_tr PF00083.24 OAP63874.1 - 4.1 6.2 27.8 15 4.3 24.6 2.8 1 1 1 2 2 2 0 Sugar (and other) transporter HTH_26 PF13443.6 OAP63875.1 - 0.068 13.6 0.1 0.13 12.7 0.1 1.4 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain PMT PF02366.18 OAP63876.1 - 2.3e-84 282.8 16.9 4.2e-84 282.0 16.9 1.4 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 OAP63876.1 - 1.1e-67 227.5 5.2 1.1e-67 227.5 5.2 3.4 2 1 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 OAP63876.1 - 3.6e-16 59.5 0.0 8.9e-16 58.3 0.0 1.6 1 1 0 1 1 1 1 MIR domain PMT_2 PF13231.6 OAP63876.1 - 1.1e-06 29.0 5.6 1.1e-06 29.0 5.6 4.3 5 1 1 6 6 6 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Caps_synth_CapC PF14102.6 OAP63876.1 - 6.2 7.3 9.6 0.27 11.7 1.7 2.8 3 1 0 3 3 3 0 Capsule biosynthesis CapC Sulfatase PF00884.23 OAP63877.1 - 4.3e-58 197.1 0.0 5.4e-58 196.8 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Choline_sulf_C PF12411.8 OAP63877.1 - 1e-26 92.5 4.8 3.8e-25 87.4 2.2 2.5 1 1 1 2 2 2 2 Choline sulfatase enzyme C terminal Phosphodiest PF01663.22 OAP63877.1 - 1.3e-10 41.5 0.0 5.4e-10 39.4 0.0 1.9 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.6 OAP63877.1 - 0.00034 21.3 0.2 0.0027 18.4 0.2 2.5 1 1 1 2 2 2 1 C-terminal region of aryl-sulfatase DUF4994 PF16385.5 OAP63877.1 - 0.0098 15.8 0.0 0.48 10.4 0.0 2.4 1 1 0 1 1 1 1 Domain of unknown function DUF229 PF02995.17 OAP63877.1 - 0.019 13.6 0.0 0.029 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) DUF4976 PF16347.5 OAP63877.1 - 0.034 14.4 0.0 0.077 13.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4976) BTB PF00651.31 OAP63878.1 - 8.3e-06 26.0 0.0 5e-05 23.5 0.0 2.0 1 1 0 1 1 1 1 BTB/POZ domain SPO22 PF08631.10 OAP63880.1 - 6.7e-18 65.2 11.1 6.5e-17 61.9 2.3 3.5 4 0 0 4 4 4 3 Meiosis protein SPO22/ZIP4 like HLH PF00010.26 OAP63881.1 - 0.00015 21.6 0.1 0.00046 20.1 0.1 1.8 1 1 1 2 2 2 1 Helix-loop-helix DNA-binding domain ATXN-1_C PF12547.8 OAP63882.1 - 0.15 12.4 1.8 0.25 11.7 0.3 2.2 2 0 0 2 2 2 0 Capicua transcriptional repressor modulator bZIP_1 PF00170.21 OAP63883.1 - 0.00092 19.3 6.8 0.0023 18.0 6.8 1.6 1 0 0 1 1 1 1 bZIP transcription factor GvpL_GvpF PF06386.11 OAP63883.1 - 0.2 11.6 4.0 0.39 10.6 4.0 1.4 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF DOR PF14839.6 OAP63883.1 - 4.5 7.1 5.8 7.6 6.4 5.8 1.3 1 0 0 1 1 1 0 DOR family NmrA PF05368.13 OAP63884.1 - 6.1e-20 71.8 0.0 3.6e-14 52.9 0.0 2.1 2 0 0 2 2 2 2 NmrA-like family NAD_binding_10 PF13460.6 OAP63884.1 - 2.7e-08 33.9 1.5 1.2e-07 31.8 0.4 2.4 2 1 0 2 2 2 1 NAD(P)H-binding DUF883 PF05957.13 OAP63884.1 - 0.048 14.3 0.5 0.048 14.3 0.5 2.6 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) DUF2236 PF09995.9 OAP63885.1 - 0.053 13.7 0.1 0.088 13.0 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2236) Pkinase PF00069.25 OAP63886.1 - 2.5e-21 76.2 0.0 3.2e-21 75.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP63886.1 - 5e-11 42.4 0.0 7.1e-11 41.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAP63886.1 - 2.6e-08 33.1 0.0 4.4e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase ABC1 PF03109.16 OAP63886.1 - 0.0059 16.8 0.0 0.016 15.3 0.0 1.7 2 0 0 2 2 2 1 ABC1 family Kdo PF06293.14 OAP63886.1 - 0.0073 15.7 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OAP63886.1 - 0.025 14.5 0.1 0.39 10.6 0.0 2.4 2 1 1 3 3 3 0 Phosphotransferase enzyme family SesA PF17107.5 OAP63887.1 - 0.005 17.0 0.2 0.072 13.3 0.0 2.4 2 1 0 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF4618 PF15397.6 OAP63887.1 - 0.0078 15.7 1.2 0.014 14.9 1.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4618) Synaptonemal_3 PF15191.6 OAP63887.1 - 0.05 13.4 0.4 0.16 11.8 0.2 1.9 1 1 1 2 2 2 0 Synaptonemal complex central element protein 3 YgaB PF14182.6 OAP63887.1 - 0.073 13.5 1.9 4.1 7.9 0.0 3.4 3 1 0 3 3 3 0 YgaB-like protein DUF746 PF05344.11 OAP63887.1 - 0.082 12.7 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF746) Abi_C PF14355.6 OAP63887.1 - 0.17 12.0 1.1 4.2 7.5 0.4 2.8 2 1 0 2 2 2 0 Abortive infection C-terminus DUF148 PF02520.17 OAP63887.1 - 4.9 7.3 7.0 1.1 9.4 1.8 2.4 2 2 1 3 3 3 0 Domain of unknown function DUF148 APH PF01636.23 OAP63888.1 - 0.00058 19.8 0.3 0.0063 16.5 0.3 2.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family AAA PF00004.29 OAP63889.1 - 2.9e-14 53.6 0.0 5.6e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Zot PF05707.12 OAP63889.1 - 0.042 13.5 0.0 0.061 12.9 0.0 1.3 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) AAA_5 PF07728.14 OAP63889.1 - 0.074 13.0 0.2 0.71 9.9 0.2 2.4 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 OAP63889.1 - 0.084 13.2 0.1 0.62 10.3 0.0 2.0 1 1 1 2 2 2 0 AAA domain RuvB_N PF05496.12 OAP63889.1 - 0.13 12.0 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 OAP63889.1 - 0.14 11.8 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein eIF-3_zeta PF05091.12 OAP63890.1 - 2.8e-205 683.2 0.0 3.5e-205 682.9 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF2530 PF10745.9 OAP63890.1 - 0.36 11.1 3.0 0.79 10.0 3.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2530) Pirin PF02678.16 OAP63891.1 - 7.5e-30 103.1 0.2 2e-29 101.7 0.1 1.8 2 0 0 2 2 2 1 Pirin Pirin_C PF05726.13 OAP63891.1 - 3.4e-25 88.4 0.0 4.1e-24 84.9 0.1 2.2 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.11 OAP63891.1 - 3.2e-08 33.2 0.4 7.6e-05 22.3 0.3 2.5 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 OAP63891.1 - 0.039 13.7 0.4 2.6 7.8 0.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF861) ATP_bind_2 PF03668.15 OAP63892.1 - 3.1e-05 23.4 0.0 5.5e-05 22.6 0.0 1.4 1 1 0 1 1 1 1 P-loop ATPase protein family DehI PF10778.9 OAP63892.1 - 0.14 12.3 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Halocarboxylic acid dehydrogenase DehI Zn_clus PF00172.18 OAP63893.1 - 4.7e-10 39.4 11.2 8.8e-10 38.5 11.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FMO-like PF00743.19 OAP63894.1 - 2e-20 72.7 0.1 4.1e-18 65.1 0.1 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OAP63894.1 - 1e-07 32.1 0.0 2.8e-07 30.7 0.0 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 OAP63894.1 - 1e-07 31.4 0.2 4.9e-05 22.6 0.0 3.6 4 0 0 4 4 4 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 OAP63894.1 - 7.9e-07 28.6 0.0 1.9e-05 24.1 0.0 2.7 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAP63894.1 - 0.001 18.7 0.0 0.11 12.0 0.0 3.3 1 1 0 2 2 2 1 FAD dependent oxidoreductase adh_short PF00106.25 OAP63895.1 - 3.6e-39 134.2 0.8 5e-39 133.8 0.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP63895.1 - 1.2e-28 100.2 2.8 1.7e-28 99.8 2.8 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP63895.1 - 4.6e-09 36.4 2.0 5.3e-08 33.0 0.1 2.4 3 0 0 3 3 3 1 KR domain 2-Hacid_dh_C PF02826.19 OAP63895.1 - 0.00023 20.6 0.0 0.00043 19.7 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Epimerase PF01370.21 OAP63895.1 - 0.0033 16.9 0.0 0.009 15.5 0.0 1.7 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAP63895.1 - 0.0088 15.5 0.0 0.023 14.1 0.0 1.6 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase YjeF_N PF03853.15 OAP63895.1 - 0.06 13.2 0.7 9 6.1 0.1 2.6 2 1 0 2 2 2 0 YjeF-related protein N-terminus Hyaluronidase_1 PF07212.11 OAP63895.1 - 0.12 11.6 0.1 0.43 9.8 0.0 1.8 2 0 0 2 2 2 0 Hyaluronidase protein (HylP) Ldh_1_N PF00056.23 OAP63895.1 - 0.15 12.2 0.8 0.46 10.6 0.8 1.8 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Glu_synthase PF01645.17 OAP63895.1 - 0.29 10.2 1.9 7.1 5.7 0.2 2.2 2 0 0 2 2 2 0 Conserved region in glutamate synthase MFS_1 PF07690.16 OAP63896.1 - 4.5e-28 98.2 31.3 5.6e-28 97.9 31.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily ABM PF03992.16 OAP63897.1 - 7.1e-05 22.8 0.2 0.42 10.7 0.2 2.4 2 0 0 2 2 2 2 Antibiotic biosynthesis monooxygenase Dabb PF07876.12 OAP63897.1 - 0.02 15.5 0.0 6.9 7.4 0.0 2.4 2 0 0 2 2 2 0 Stress responsive A/B Barrel Domain Oxidored_FMN PF00724.20 OAP63898.1 - 1.3e-66 225.3 0.0 4.3e-63 213.7 0.0 2.3 2 1 0 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family Lactamase_B PF00753.27 OAP63899.1 - 3.5e-12 46.7 0.2 6.2e-12 45.9 0.2 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OAP63899.1 - 0.0074 15.8 0.1 0.013 15.0 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain adh_short PF00106.25 OAP63900.1 - 4.4e-32 111.1 5.9 7.8e-32 110.3 5.9 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP63900.1 - 4e-25 88.7 3.6 6.9e-25 88.0 3.6 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP63900.1 - 3e-08 33.8 2.1 5.1e-08 33.0 2.1 1.3 1 0 0 1 1 1 1 KR domain Aldolase_II PF00596.21 OAP63901.1 - 1.1e-47 162.4 0.0 1.3e-47 162.1 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Fungal_trans PF04082.18 OAP63902.1 - 1.6e-20 73.3 0.1 3.6e-20 72.1 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP63902.1 - 7.6e-07 29.1 7.7 1.4e-06 28.3 7.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Vps4_C PF09336.10 OAP63902.1 - 0.17 11.9 0.1 1.4 9.0 0.0 2.5 3 0 0 3 3 3 0 Vps4 C terminal oligomerisation domain adh_short_C2 PF13561.6 OAP63903.1 - 1.4e-64 217.8 6.4 1.7e-64 217.6 6.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP63903.1 - 4.4e-45 153.6 5.7 5.4e-45 153.3 5.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAP63903.1 - 3e-13 50.1 4.0 4.3e-13 49.6 4.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAP63903.1 - 0.00017 21.1 1.2 0.0013 18.3 1.2 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 OAP63903.1 - 0.00022 20.5 0.1 0.00039 19.6 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 OAP63903.1 - 0.00026 21.3 0.3 0.00058 20.1 0.2 1.6 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain 3HCDH_N PF02737.18 OAP63903.1 - 0.00069 19.5 0.4 0.00069 19.5 0.4 1.7 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 OAP63903.1 - 0.0025 17.3 0.1 0.0039 16.7 0.1 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Ldh_1_N PF00056.23 OAP63903.1 - 0.014 15.5 0.3 0.031 14.4 0.3 1.6 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 OAP63903.1 - 0.058 13.0 0.4 0.4 10.2 0.1 2.1 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Sugar_tr PF00083.24 OAP63904.1 - 4e-78 263.3 18.1 4.5e-78 263.1 18.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP63904.1 - 1.4e-21 76.9 55.9 8.7e-18 64.4 29.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Flavin_Reduct PF01613.18 OAP63905.1 - 3e-14 53.4 0.1 4.2e-14 52.9 0.1 1.1 1 0 0 1 1 1 1 Flavin reductase like domain adh_short PF00106.25 OAP63907.1 - 5.7e-13 48.8 0.0 3.7e-08 33.1 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAP63907.1 - 3.8e-07 29.9 0.0 1.4e-05 24.7 0.0 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase T4-Gluco-transf PF09198.10 OAP63907.1 - 0.045 13.3 0.1 0.14 11.8 0.0 1.8 2 0 0 2 2 2 0 Bacteriophage T4 beta-glucosyltransferase Fungal_trans_2 PF11951.8 OAP63908.1 - 0.006 15.4 0.3 0.096 11.5 0.0 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Flavin_Reduct PF01613.18 OAP63909.1 - 1.3e-24 87.0 0.0 1.5e-24 86.8 0.0 1.0 1 0 0 1 1 1 1 Flavin reductase like domain FAD_binding_3 PF01494.19 OAP63910.1 - 5.1e-22 78.6 0.0 5.5e-20 71.9 0.0 2.8 1 1 0 1 1 1 1 FAD binding domain SE PF08491.10 OAP63910.1 - 0.00022 20.4 0.0 0.00033 19.8 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase Lycopene_cycl PF05834.12 OAP63910.1 - 0.00071 18.7 0.1 0.27 10.3 0.0 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein NAD_binding_9 PF13454.6 OAP63910.1 - 0.013 15.5 0.0 0.023 14.7 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding K_oxygenase PF13434.6 OAP63910.1 - 0.094 11.8 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 OAP63910.1 - 0.5 9.6 2.2 1.7 7.8 0.0 2.5 3 0 0 3 3 3 0 Thi4 family Peptidase_C2 PF00648.21 OAP63911.1 - 5.1e-27 94.7 0.0 8.2e-27 94.0 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 OAP63911.1 - 1.6e-11 44.6 0.0 4.3e-10 40.0 0.0 2.5 2 0 0 2 2 2 1 Calpain large subunit, domain III DUF4164 PF13747.6 OAP63911.1 - 0.065 13.5 0.5 0.13 12.6 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) Mito_carr PF00153.27 OAP63912.1 - 3.8e-56 187.0 0.3 2.2e-21 75.6 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein NTP_transf_6 PF06042.11 OAP63912.1 - 0.025 14.4 0.0 0.041 13.7 0.0 1.3 1 0 0 1 1 1 0 Nucleotidyltransferase GCD14 PF08704.10 OAP63913.1 - 6.4e-08 32.6 0.0 6.2e-05 22.8 0.0 2.3 2 0 0 2 2 2 2 tRNA methyltransferase complex GCD14 subunit GCD14_N PF14801.6 OAP63913.1 - 0.00096 18.9 0.0 0.0019 18.0 0.0 1.5 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit N-term Big_11 PF18200.1 OAP63913.1 - 0.11 12.5 0.0 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 Bacterial Ig-like domain Metallophos PF00149.28 OAP63914.1 - 3.1e-16 60.5 1.0 6e-16 59.6 1.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase NAD_binding_1 PF00175.21 OAP63915.1 - 2.6e-05 24.8 0.3 0.00024 21.7 0.3 2.2 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 OAP63915.1 - 6.6e-05 23.1 0.1 0.0091 16.1 0.1 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_6 PF00970.24 OAP63915.1 - 0.016 15.5 0.0 0.032 14.6 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain Amino_oxidase PF01593.24 OAP63916.1 - 8.9e-85 285.7 0.0 2.5e-82 277.6 0.0 2.3 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase SWIRM PF04433.17 OAP63916.1 - 9.9e-13 48.2 0.0 2.3e-12 47.0 0.0 1.6 1 0 0 1 1 1 1 SWIRM domain NAD_binding_8 PF13450.6 OAP63916.1 - 6.9e-09 35.8 0.0 3e-08 33.8 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HMG_box PF00505.19 OAP63916.1 - 4e-07 30.4 3.9 1.2e-05 25.6 3.6 2.4 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 OAP63916.1 - 9.3e-06 26.2 3.6 2.7e-05 24.6 3.6 1.9 1 0 0 1 1 1 1 HMG-box domain DAO PF01266.24 OAP63916.1 - 1.1e-05 25.2 0.0 2.6e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 OAP63916.1 - 0.0011 19.0 0.0 0.032 14.2 0.0 3.0 3 1 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 OAP63916.1 - 0.0055 16.0 0.0 0.03 13.6 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Putative_PNPOx PF01243.20 OAP63917.1 - 0.003 17.7 0.0 0.15 12.3 0.0 2.2 2 0 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase Trimer_CC PF08954.11 OAP63918.1 - 0.015 14.9 0.4 0.039 13.5 0.4 1.7 1 0 0 1 1 1 0 Trimerisation motif Pkinase PF00069.25 OAP63919.1 - 4.8e-36 124.5 0.0 6.7e-36 124.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP63919.1 - 1.3e-12 47.6 0.0 2.2e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAP63919.1 - 2.7e-05 23.2 0.0 4.3e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OAP63919.1 - 0.0054 16.7 0.1 0.02 14.8 0.1 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 OAP63919.1 - 0.0082 15.8 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 OAP63919.1 - 0.029 13.7 0.1 0.052 12.9 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Lpp-LpqN PF10738.9 OAP63919.1 - 0.092 12.2 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Probable lipoprotein LpqN Kinase-like PF14531.6 OAP63919.1 - 0.14 11.5 0.0 0.26 10.5 0.0 1.5 1 0 0 1 1 1 0 Kinase-like Abhydrolase_1 PF00561.20 OAP63921.1 - 6.5e-17 62.0 0.1 6.6e-15 55.4 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAP63921.1 - 2.8e-14 54.3 4.1 7.9e-14 52.8 4.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAP63921.1 - 0.025 13.8 0.0 1.1 8.4 0.0 2.1 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 OAP63921.1 - 0.033 13.1 0.0 0.057 12.3 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase enzyme DLH PF01738.18 OAP63921.1 - 0.11 12.1 0.0 2.9 7.4 0.0 2.3 2 1 0 2 2 2 0 Dienelactone hydrolase family Glucosamine_iso PF01182.20 OAP63922.1 - 1.2e-68 231.3 0.0 1.4e-68 231.2 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase RRM_1 PF00076.22 OAP63923.1 - 3.1e-15 55.8 0.0 1.9e-12 46.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Apt1 PF10351.9 OAP63923.1 - 0.89 8.3 10.3 1.4 7.6 10.3 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain TFIIA PF03153.13 OAP63923.1 - 1.5 8.7 21.7 2 8.3 21.7 1.4 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PPP4R2 PF09184.11 OAP63923.1 - 3 7.4 16.5 4.4 6.8 16.5 1.2 1 0 0 1 1 1 0 PPP4R2 TRAP_alpha PF03896.16 OAP63923.1 - 9.2 5.4 6.0 17 4.5 6.0 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Methyltransf_23 PF13489.6 OAP63924.1 - 4.7e-23 81.8 0.0 1.5e-22 80.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAP63924.1 - 1.6e-11 44.7 0.0 6.7e-11 42.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAP63924.1 - 1.2e-10 41.9 0.0 2.5e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAP63924.1 - 1.2e-10 42.0 0.0 1.6e-09 38.4 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAP63924.1 - 5.4e-09 36.0 0.0 0.0017 18.1 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain MTS PF05175.14 OAP63924.1 - 0.00036 20.1 0.0 0.0068 16.0 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase small domain DUF938 PF06080.12 OAP63924.1 - 0.01 15.6 0.0 0.02 14.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF938) PrmA PF06325.13 OAP63924.1 - 0.016 14.6 0.0 0.028 13.8 0.0 1.5 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.17 OAP63924.1 - 0.025 14.0 0.0 0.072 12.6 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase Ribosomal_L29 PF00831.23 OAP63924.1 - 0.032 14.2 0.2 0.069 13.1 0.2 1.5 1 0 0 1 1 1 0 Ribosomal L29 protein Methyltransf_16 PF10294.9 OAP63924.1 - 0.035 13.8 0.0 0.056 13.2 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_2 PF00891.18 OAP63925.1 - 5.9e-17 61.7 0.0 1.5e-14 53.8 0.0 2.4 1 1 0 1 1 1 1 O-methyltransferase domain Phage_lysozyme PF00959.19 OAP63927.1 - 5.4e-05 23.6 0.1 8.2e-05 23.0 0.1 1.4 1 1 0 1 1 1 1 Phage lysozyme MMR_HSR1 PF01926.23 OAP63928.1 - 3.1e-06 27.3 0.0 5.1e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase PTS_EIIC PF02378.18 OAP63928.1 - 0.033 13.2 0.1 0.046 12.7 0.1 1.1 1 0 0 1 1 1 0 Phosphotransferase system, EIIC Peroxin-13_N PF04088.13 OAP63929.1 - 1.6e-48 164.6 0.0 3.4e-48 163.6 0.0 1.6 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.17 OAP63929.1 - 4e-09 36.0 0.0 7.2e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 OAP63929.1 - 6.4e-09 35.3 0.0 1.1e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 OAP63929.1 - 0.00016 21.5 0.0 0.00029 20.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain hSH3 PF14603.6 OAP63929.1 - 0.042 14.3 0.0 0.077 13.4 0.0 1.3 1 0 0 1 1 1 0 Helically-extended SH3 domain GRP PF07172.11 OAP63929.1 - 3.8 8.2 20.8 9.7 7.0 20.2 1.9 2 0 0 2 2 2 0 Glycine rich protein family Vps8 PF12816.7 OAP63930.1 - 2.7e-53 180.4 0.0 5.3e-53 179.5 0.0 1.5 1 0 0 1 1 1 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.20 OAP63930.1 - 2.2e-05 24.4 0.0 0.013 15.4 0.0 2.6 2 0 0 2 2 2 2 Region in Clathrin and VPS zf-C3H2C3 PF17122.5 OAP63930.1 - 3.3e-05 23.8 0.1 9.1e-05 22.4 0.1 1.7 1 0 0 1 1 1 1 Zinc-finger ANAPC4_WD40 PF12894.7 OAP63930.1 - 0.06 13.6 0.1 0.36 11.2 0.0 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain zf-RING_5 PF14634.6 OAP63930.1 - 0.084 12.8 0.6 0.25 11.3 0.2 1.9 2 0 0 2 2 2 0 zinc-RING finger domain zf-RING_11 PF17123.5 OAP63930.1 - 0.095 12.5 0.2 0.23 11.3 0.2 1.6 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_2 PF13639.6 OAP63930.1 - 0.16 12.4 0.2 0.41 11.0 0.2 1.7 1 0 0 1 1 1 0 Ring finger domain zf-rbx1 PF12678.7 OAP63930.1 - 0.17 12.2 0.1 0.44 10.9 0.1 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain Glyco_hydro_16 PF00722.21 OAP63931.1 - 7.3e-07 28.8 0.5 1.7e-06 27.6 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 DUF4448 PF14610.6 OAP63933.1 - 0.001 18.9 0.0 0.0016 18.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) SKG6 PF08693.10 OAP63933.1 - 0.0032 16.8 0.2 0.0064 15.9 0.2 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain TMEM154 PF15102.6 OAP63933.1 - 0.047 13.6 5.4 0.049 13.5 3.2 2.1 1 1 0 1 1 1 0 TMEM154 protein family RIFIN PF02009.16 OAP63933.1 - 0.077 12.9 0.3 0.11 12.4 0.3 1.1 1 0 0 1 1 1 0 Rifin DUF1177 PF06675.11 OAP63933.1 - 0.16 10.8 0.3 0.25 10.1 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1177) DUF4083 PF13314.6 OAP63933.1 - 0.28 11.2 0.4 0.57 10.2 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) UPF0114 PF03350.16 OAP63934.1 - 0.032 14.4 1.5 2.8 8.2 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized protein family, UPF0114 EF-hand_6 PF13405.6 OAP63935.1 - 1.8e-08 33.7 0.0 0.0015 18.3 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 OAP63935.1 - 5.2e-07 28.8 0.0 0.0055 16.2 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 OAP63935.1 - 6.3e-06 25.4 0.4 0.0079 15.6 0.1 2.4 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 OAP63935.1 - 0.0002 21.7 0.0 0.00091 19.6 0.0 2.0 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 OAP63935.1 - 0.076 12.9 0.0 0.83 9.6 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain pair Afi1 PF07792.12 OAP63936.1 - 1.1e-41 142.5 0.1 1.6e-41 141.9 0.1 1.3 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.10 OAP63936.1 - 4.4e-38 129.7 0.0 1.1e-37 128.4 0.0 1.7 2 0 0 2 2 2 1 Stabilization of polarity axis Avl9 PF09794.9 OAP63936.1 - 6.5e-08 31.7 0.0 0.058 12.1 0.0 3.8 3 1 1 4 4 4 3 Transport protein Avl9 TFIIF_alpha PF05793.12 OAP63936.1 - 0.0046 15.6 1.8 0.0073 14.9 1.8 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF2347 PF09804.9 OAP63936.1 - 0.021 14.4 0.0 0.068 12.7 0.0 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) Nop14 PF04147.12 OAP63936.1 - 0.41 8.8 4.1 0.61 8.2 4.1 1.1 1 0 0 1 1 1 0 Nop14-like family Herpes_pp85 PF04637.12 OAP63937.1 - 4.7 5.5 6.8 7.4 4.9 6.8 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) MFS_1 PF07690.16 OAP63939.1 - 1e-34 120.0 40.8 1e-34 120.0 40.8 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAP63939.1 - 4.1e-08 32.5 14.3 4.1e-08 32.5 14.3 3.0 2 1 0 3 3 3 2 Sugar (and other) transporter Cation_ATPase_C PF00689.21 OAP63939.1 - 0.0002 21.1 8.9 0.0002 21.1 8.9 2.2 2 1 0 2 2 2 1 Cation transporting ATPase, C-terminus Chitin_synth_2 PF03142.15 OAP63942.1 - 3e-288 956.7 0.1 9.5e-288 955.1 0.0 1.7 2 0 0 2 2 2 1 Chitin synthase Glyco_trans_2_3 PF13632.6 OAP63942.1 - 2.8e-12 46.9 4.8 1.6e-11 44.5 4.8 2.3 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 OAP63942.1 - 3e-11 43.6 0.0 1e-08 35.4 0.0 2.5 2 1 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 OAP63942.1 - 0.00023 20.7 0.1 0.0031 17.0 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 OAP63942.1 - 0.0055 16.5 0.0 0.084 12.7 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 2 Sel1 PF08238.12 OAP63943.1 - 1.7e-37 127.0 27.8 5.9e-06 26.8 0.1 7.6 7 0 0 7 7 7 7 Sel1 repeat TPR_19 PF14559.6 OAP63943.1 - 3.1 8.4 5.7 25 5.5 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat MFS_1 PF07690.16 OAP63944.1 - 6.1e-39 133.9 28.9 6.1e-39 133.9 28.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAP63944.1 - 9.3e-07 28.0 26.5 1.5e-06 27.4 26.0 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_4 PF06779.14 OAP63944.1 - 7.2e-06 25.5 3.1 7.2e-06 25.5 3.1 2.2 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB AnmK PF03702.14 OAP63946.1 - 3.9e-71 240.1 0.0 1.9e-68 231.2 0.0 2.0 1 1 0 1 1 1 1 Anhydro-N-acetylmuramic acid kinase Ank_5 PF13857.6 OAP63946.1 - 0.076 13.4 0.1 40 4.7 0.0 3.4 4 0 0 4 4 4 0 Ankyrin repeats (many copies) Sugar_tr PF00083.24 OAP63947.1 - 3.8e-79 266.7 28.5 4.4e-79 266.5 28.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP63947.1 - 2.5e-18 66.1 23.1 2.5e-18 66.1 23.1 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Aldo_ket_red PF00248.21 OAP63948.1 - 3.3e-66 223.5 0.0 3.7e-66 223.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family HAD PF12710.7 OAP63948.1 - 0.0057 17.1 0.0 0.015 15.8 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase AMP-binding PF00501.28 OAP63949.1 - 1.3e-88 297.4 0.0 1.7e-88 297.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAP63949.1 - 8.2e-11 42.7 0.0 2e-10 41.5 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Succ_DH_flav_C PF02910.20 OAP63950.1 - 0.12 12.4 1.8 0.17 11.9 1.8 1.2 1 0 0 1 1 1 0 Fumarate reductase flavoprotein C-term MFS_1 PF07690.16 OAP63951.1 - 9.2e-35 120.2 61.3 9.2e-35 120.2 61.3 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAP63951.1 - 3.5e-10 39.4 10.9 3.5e-10 39.4 10.9 2.4 2 0 0 2 2 2 2 Sugar (and other) transporter Ldi PF18566.1 OAP63952.1 - 1.1e-145 485.1 0.0 1.3e-145 484.8 0.0 1.1 1 0 0 1 1 1 1 Linalool dehydratase/isomerase HATPase_c PF02518.26 OAP63953.1 - 2.3e-26 92.5 0.3 4.4e-26 91.6 0.3 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 OAP63953.1 - 2.3e-19 69.2 0.1 7.3e-19 67.6 0.1 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Response_reg PF00072.24 OAP63953.1 - 2.1e-16 60.1 0.0 7.5e-16 58.3 0.0 2.0 1 0 0 1 1 1 1 Response regulator receiver domain PAS_3 PF08447.12 OAP63953.1 - 2.9e-16 59.5 0.2 1e-15 57.8 0.4 1.9 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.10 OAP63953.1 - 3.2e-12 46.7 0.0 4.8e-07 30.0 0.0 4.5 4 1 0 4 4 4 2 PAS fold PAS_9 PF13426.7 OAP63953.1 - 5.9e-11 42.6 0.0 3e-06 27.4 0.0 4.3 4 0 0 4 4 4 2 PAS domain PAS PF00989.25 OAP63953.1 - 6.9e-07 29.3 0.0 0.037 14.0 0.0 4.1 4 0 0 4 4 4 2 PAS fold HATPase_c_3 PF13589.6 OAP63953.1 - 0.0068 16.2 0.0 0.018 14.9 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF4172 PF13776.6 OAP63953.1 - 0.11 12.8 0.2 0.34 11.3 0.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4172) UQ_con PF00179.26 OAP63954.1 - 1.3e-42 144.8 0.0 1.2e-28 99.5 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OAP63954.1 - 7.2e-08 32.2 0.0 0.00044 19.9 0.0 2.4 2 0 0 2 2 2 2 Prokaryotic E2 family B UEV PF05743.13 OAP63954.1 - 0.003 17.4 0.1 0.012 15.5 0.0 2.0 2 1 0 2 2 2 1 UEV domain 3Beta_HSD PF01073.19 OAP63955.1 - 5.2e-39 133.9 0.0 3.5e-34 118.1 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 OAP63955.1 - 8.9e-16 58.1 0.0 1.6e-12 47.4 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 OAP63955.1 - 6.7e-11 41.8 0.0 5.8e-08 32.2 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein GDP_Man_Dehyd PF16363.5 OAP63955.1 - 9.6e-10 38.4 0.0 6.4e-07 29.1 0.0 2.3 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 OAP63955.1 - 9.9e-08 31.4 0.1 6.1e-07 28.8 0.0 2.0 2 0 0 2 2 2 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 OAP63955.1 - 0.002 17.4 0.0 1 8.5 0.0 2.8 3 0 0 3 3 3 2 Polysaccharide biosynthesis protein Pkinase PF00069.25 OAP63956.1 - 5.4e-60 203.0 0.0 8.6e-39 133.5 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAP63956.1 - 1.7e-26 93.1 0.0 2.6e-20 72.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.24 OAP63956.1 - 8.6e-13 48.4 0.1 2.2e-12 47.2 0.1 1.8 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.6 OAP63956.1 - 6e-08 32.3 0.0 4.1e-05 23.0 0.0 2.4 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 OAP63956.1 - 5.1e-05 23.3 0.2 0.0032 17.4 0.1 3.0 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 OAP63956.1 - 0.0081 15.5 0.0 0.016 14.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OAP63956.1 - 0.0091 15.0 0.0 0.019 13.9 0.0 1.5 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 OAP63956.1 - 0.069 12.8 0.0 13 5.3 0.0 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 PAS_4 PF08448.10 OAP63956.1 - 0.076 13.3 0.0 0.17 12.2 0.0 1.6 1 0 0 1 1 1 0 PAS fold PAS PF00989.25 OAP63956.1 - 0.079 13.0 0.0 0.21 11.6 0.0 1.7 1 0 0 1 1 1 0 PAS fold Seadorna_VP7 PF07387.11 OAP63956.1 - 0.14 11.2 0.1 0.22 10.5 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 PTR2 PF00854.21 OAP63958.1 - 7.2e-90 301.7 6.3 1.8e-89 300.4 6.3 1.6 1 1 0 1 1 1 1 POT family MFS_1 PF07690.16 OAP63958.1 - 8.8e-06 24.9 23.2 0.0031 16.5 4.7 2.8 3 0 0 3 3 3 2 Major Facilitator Superfamily DUF4094 PF13334.6 OAP63958.1 - 0.011 16.1 0.4 3.6 8.1 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) CsrA PF02599.16 OAP63958.1 - 0.27 11.2 0.7 2.9 7.9 0.0 2.3 2 0 0 2 2 2 0 Global regulator protein family zf-RING_2 PF13639.6 OAP63959.1 - 6.4e-12 45.6 7.6 9.7e-12 45.0 7.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 OAP63959.1 - 7.4e-08 32.0 3.0 1.2e-07 31.3 3.0 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 OAP63959.1 - 1.3e-07 31.4 6.6 2e-07 30.7 6.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAP63959.1 - 6.2e-07 29.2 5.3 1e-06 28.5 5.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OAP63959.1 - 6.4e-06 26.4 10.6 2.3e-05 24.6 10.6 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 OAP63959.1 - 1.2e-05 25.1 4.5 2e-05 24.5 4.5 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 OAP63959.1 - 0.001 18.9 3.5 0.0018 18.1 3.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAP63959.1 - 0.0014 18.6 1.5 0.0014 18.6 1.5 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 OAP63959.1 - 0.0026 17.8 4.2 0.0059 16.6 4.2 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 OAP63959.1 - 0.015 15.1 7.9 0.025 14.4 7.9 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.5 OAP63959.1 - 0.12 12.0 5.4 0.21 11.2 5.4 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type PHD PF00628.29 OAP63959.1 - 0.2 11.6 7.0 0.46 10.4 7.0 1.6 1 0 0 1 1 1 0 PHD-finger FANCL_C PF11793.8 OAP63959.1 - 0.38 11.0 4.1 1.1 9.4 4.1 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain Prok-RING_4 PF14447.6 OAP63959.1 - 0.42 10.5 6.3 1.3 9.0 6.4 1.7 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 OAD_gamma PF04277.13 OAP63959.1 - 0.83 10.3 0.0 0.83 10.3 0.0 3.0 3 1 0 3 3 1 0 Oxaloacetate decarboxylase, gamma chain zf-C3HC4_4 PF15227.6 OAP63959.1 - 0.98 9.6 5.0 2.7 8.2 5.0 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3H2C3 PF17122.5 OAP63959.1 - 1.8 8.7 5.5 4.4 7.4 5.5 1.6 1 1 0 1 1 1 0 Zinc-finger RINGv PF12906.7 OAP63959.1 - 1.9 8.7 6.9 3.7 7.7 6.9 1.5 1 0 0 1 1 1 0 RING-variant domain TRI12 PF06609.13 OAP63960.1 - 1.9e-25 89.4 23.0 2.7e-25 88.8 23.0 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAP63960.1 - 8e-21 74.3 38.1 8e-21 74.3 38.1 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Fst_toxin PF13955.6 OAP63960.1 - 0.12 12.3 5.0 0.58 10.1 5.0 2.1 1 0 0 1 1 1 0 Toxin Fst, type I toxin-antitoxin system DUF2181 PF10223.9 OAP63960.1 - 0.2 11.1 0.0 0.37 10.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2181) p450 PF00067.22 OAP63961.1 - 7.8e-52 176.5 0.0 1e-51 176.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 OAP63962.1 - 1.3e-40 139.4 47.0 4.3e-40 137.7 47.0 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans PF04082.18 OAP63963.1 - 2.8e-16 59.4 0.0 4.6e-16 58.7 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP63963.1 - 8.6e-10 38.6 9.4 8.6e-10 38.6 9.4 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HET PF06985.11 OAP63964.1 - 0.015 15.7 0.2 0.015 15.7 0.2 2.3 2 1 1 3 3 3 0 Heterokaryon incompatibility protein (HET) TAFII55_N PF04658.13 OAP63965.1 - 5.2e-46 156.3 0.0 1.1e-45 155.2 0.0 1.6 1 0 0 1 1 1 1 TAFII55 protein conserved region Sigma70_ner PF04546.13 OAP63965.1 - 0.012 15.5 10.3 0.012 15.5 10.3 2.0 2 0 0 2 2 2 0 Sigma-70, non-essential region BLOC1S3 PF15753.5 OAP63965.1 - 0.055 13.6 7.3 0.13 12.4 7.3 1.6 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 GCIP PF13324.6 OAP63965.1 - 0.11 12.1 5.7 0.18 11.4 5.7 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting DUF1664 PF07889.12 OAP63965.1 - 0.44 10.6 3.2 0.94 9.5 3.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) BrnA_antitoxin PF14384.6 OAP63965.1 - 0.56 10.7 4.9 0.52 10.8 0.1 3.1 2 0 0 2 2 2 0 BrnA antitoxin of type II toxin-antitoxin system UPF0242 PF06785.11 OAP63965.1 - 1.2 9.2 7.6 2.1 8.4 7.6 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Pox_RNA_Pol_19 PF05320.12 OAP63965.1 - 6.4 6.7 8.6 13 5.7 8.6 1.5 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit RRN3 PF05327.11 OAP63965.1 - 8.1 4.8 5.5 12 4.3 5.5 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Bromo_TP PF07524.13 OAP63966.1 - 5.9e-11 42.2 0.0 1e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated TFIID-31kDa PF02291.15 OAP63966.1 - 0.0056 16.7 0.0 0.0087 16.1 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit TPR_12 PF13424.6 OAP63968.1 - 0.078 13.3 2.8 27 5.2 0.2 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Ferritin_2 PF13668.6 OAP63969.1 - 4.1e-19 69.1 0.0 9.8e-19 67.9 0.0 1.6 2 0 0 2 2 2 1 Ferritin-like domain Ubiq_cyt_C_chap PF03981.12 OAP63970.1 - 5.2e-27 94.7 0.4 1.7e-25 89.7 0.5 2.1 2 0 0 2 2 2 2 Ubiquinol-cytochrome C chaperone DnaJ_C PF01556.18 OAP63972.1 - 3e-25 89.0 0.0 4.2e-25 88.6 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 OAP63972.1 - 1.1e-21 76.7 1.1 2e-21 75.9 1.1 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 OAP63972.1 - 3.7e-14 52.8 17.8 6.5e-14 52.0 17.8 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 OAP63972.1 - 6.5e-05 22.8 9.2 0.002 18.1 1.4 2.4 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 OAP63972.1 - 0.01 15.9 6.8 0.19 11.8 0.9 2.3 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA SRR PF07709.11 OAP63972.1 - 0.023 15.0 0.3 1.3 9.7 0.0 2.9 3 0 0 3 3 3 0 Seven Residue Repeat TackOD1 PF18551.1 OAP63972.1 - 2.6 7.7 8.4 5.4 6.6 0.9 2.3 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 Fungal_trans PF04082.18 OAP63977.1 - 1.3e-10 40.8 0.3 3.1e-10 39.5 0.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain MMS19_C PF12460.8 OAP63978.1 - 2.8e-94 316.6 11.6 2.1e-91 307.2 7.5 3.3 3 0 0 3 3 3 2 RNAPII transcription regulator C-terminal MMS19_N PF14500.6 OAP63978.1 - 8.3e-93 310.7 1.2 1.2e-90 303.6 0.0 3.8 3 1 0 3 3 3 1 Dos2-interacting transcription regulator of RNA-Pol-II HEAT_EZ PF13513.6 OAP63978.1 - 0.00047 20.6 4.6 0.24 12.0 0.1 5.3 4 1 1 5 5 5 1 HEAT-like repeat Cnd1 PF12717.7 OAP63978.1 - 0.00074 19.6 0.8 11 6.0 0.0 4.7 4 1 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 OAP63978.1 - 0.00075 19.8 11.9 0.39 11.1 0.1 6.0 7 1 0 7 7 7 2 HEAT repeats RTP1_C1 PF10363.9 OAP63978.1 - 0.035 14.3 0.4 0.86 9.8 0.0 3.3 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 DegS PF05384.11 OAP63978.1 - 0.089 12.3 0.8 0.26 10.8 0.8 1.7 1 0 0 1 1 1 0 Sensor protein DegS TcdB_N PF12918.7 OAP63978.1 - 0.11 12.9 0.6 12 6.3 0.0 3.0 3 0 0 3 3 3 0 TcdB toxin N-terminal helical domain Complex1_51K PF01512.17 OAP63978.1 - 0.2 11.5 0.2 0.38 10.6 0.2 1.4 1 0 0 1 1 1 0 Respiratory-chain NADH dehydrogenase 51 Kd subunit HEAT PF02985.22 OAP63978.1 - 0.35 11.3 6.3 25 5.5 0.0 5.8 5 0 0 5 5 5 0 HEAT repeat Adaptin_N PF01602.20 OAP63978.1 - 1.3 7.5 7.2 4.4 5.7 0.3 4.2 5 2 0 5 5 5 0 Adaptin N terminal region OB_NTP_bind PF07717.16 OAP63979.1 - 5e-22 78.1 0.0 1.3e-21 76.7 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 OAP63979.1 - 2.1e-19 69.8 0.0 2.1e-19 69.8 0.0 3.7 3 2 0 3 3 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 OAP63979.1 - 3.3e-13 50.0 0.0 8.6e-13 48.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 OAP63979.1 - 5.8e-08 32.7 0.0 1.2e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 OAP63979.1 - 1.5e-05 25.3 0.0 5e-05 23.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 OAP63979.1 - 3.5e-05 23.6 0.1 8.8e-05 22.3 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OAP63979.1 - 5.8e-05 23.5 1.1 0.00011 22.6 0.1 2.0 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 OAP63979.1 - 6.2e-05 22.2 0.1 0.00018 20.6 0.0 1.8 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_23 PF13476.6 OAP63979.1 - 0.04 14.4 0.0 0.04 14.4 0.0 3.6 1 1 0 2 2 1 0 AAA domain Sigma54_activ_2 PF14532.6 OAP63979.1 - 0.047 13.8 0.0 0.17 12.0 0.0 2.0 2 0 0 2 2 1 0 Sigma-54 interaction domain ABC_tran PF00005.27 OAP63979.1 - 0.05 14.1 3.1 0.072 13.6 0.2 2.6 1 1 1 2 2 2 0 ABC transporter cobW PF02492.19 OAP63979.1 - 0.081 12.5 0.3 3 7.4 0.2 2.8 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain SRP54 PF00448.22 OAP63979.1 - 0.087 12.4 0.2 0.24 11.0 0.2 1.8 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain Halogen_Hydrol PF10112.9 OAP63979.1 - 0.55 10.2 5.7 0.058 13.4 0.6 1.9 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein AAA_14 PF13173.6 OAP63979.1 - 0.62 10.1 2.4 18 5.4 0.1 3.1 2 1 0 2 2 2 0 AAA domain THF_DHG_CYH PF00763.23 OAP63980.1 - 7.4e-23 81.0 0.0 1.5e-22 80.1 0.0 1.5 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 OAP63980.1 - 1.3e-11 44.1 0.1 1.6e-08 34.0 0.0 2.6 2 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain RTBV_P12 PF06361.11 OAP63980.1 - 0.026 14.9 0.6 0.063 13.7 0.6 1.6 1 0 0 1 1 1 0 Rice tungro bacilliform virus P12 protein CdiI_N PF18228.1 OAP63980.1 - 0.19 11.5 0.1 0.4 10.5 0.1 1.5 1 0 0 1 1 1 0 CdiI N-terminal domain bZIP_1 PF00170.21 OAP63982.1 - 3.4e-06 27.1 11.7 5.6e-06 26.4 11.7 1.4 1 0 0 1 1 1 1 bZIP transcription factor DUF3631 PF12307.8 OAP63982.1 - 0.00017 21.9 0.4 0.00023 21.4 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3631) TMF_TATA_bd PF12325.8 OAP63982.1 - 0.00021 21.5 2.3 0.00034 20.8 2.3 1.3 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding FmiP_Thoc5 PF09766.9 OAP63982.1 - 0.00075 18.9 0.2 0.00099 18.5 0.2 1.1 1 0 0 1 1 1 1 Fms-interacting protein/Thoc5 DUF4618 PF15397.6 OAP63982.1 - 0.0012 18.3 0.6 0.0016 17.9 0.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4618) UPF0242 PF06785.11 OAP63982.1 - 0.0057 16.8 0.5 0.0069 16.5 0.5 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus CLZ PF16526.5 OAP63982.1 - 0.018 15.4 4.3 0.042 14.2 3.9 1.9 1 1 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF1043 PF06295.12 OAP63982.1 - 0.033 14.2 1.3 0.054 13.5 1.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) bZIP_2 PF07716.15 OAP63982.1 - 0.038 14.1 11.7 0.069 13.2 10.8 1.8 1 1 1 2 2 2 0 Basic region leucine zipper HSP70 PF00012.20 OAP63982.1 - 0.05 11.8 0.3 0.062 11.5 0.3 1.0 1 0 0 1 1 1 0 Hsp70 protein Atg14 PF10186.9 OAP63982.1 - 0.059 12.5 2.7 0.068 12.2 2.7 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 bZIP_Maf PF03131.17 OAP63982.1 - 0.092 13.3 6.6 0.2 12.2 6.6 1.6 1 0 0 1 1 1 0 bZIP Maf transcription factor Ima1_N PF09779.9 OAP63982.1 - 0.18 12.7 0.1 0.27 12.1 0.1 1.2 1 0 0 1 1 1 0 Ima1 N-terminal domain Cyt-b5 PF00173.28 OAP63983.1 - 2.7e-20 72.3 0.2 3e-20 72.1 0.2 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain V-ATPase_H_C PF11698.8 OAP63983.1 - 0.089 12.9 0.0 0.15 12.1 0.0 1.5 1 1 0 1 1 1 0 V-ATPase subunit H bZIP_1 PF00170.21 OAP63984.1 - 1.4e-06 28.3 3.4 1.4e-06 28.3 3.4 1.9 1 1 1 2 2 2 1 bZIP transcription factor DUF5446 PF17522.2 OAP63984.1 - 0.42 10.8 1.9 0.96 9.7 0.6 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5446) Ribosomal_L44 PF00935.19 OAP63987.1 - 2.3e-36 124.1 12.0 3.9e-36 123.4 12.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L44 Cathelicidins PF00666.17 OAP63987.1 - 0.089 13.1 0.9 0.089 13.1 0.9 1.6 2 0 0 2 2 2 0 Cathelicidin Anillin_N PF16018.5 OAP63988.1 - 1.8 9.2 7.8 0.21 12.2 3.5 1.6 2 0 0 2 2 2 0 Anillin N-terminus DUF3824 PF12868.7 OAP63989.1 - 4.7e-20 72.8 48.0 4.7e-20 72.8 48.0 10.3 3 2 8 11 11 11 4 Domain of unknwon function (DUF3824) PA PF02225.22 OAP63989.1 - 0.21 11.6 1.3 20 5.3 0.1 2.9 2 0 0 2 2 2 0 PA domain SfLAP PF11139.8 OAP63989.1 - 4.7 6.6 8.2 1.2e+02 1.9 8.2 2.6 1 1 0 1 1 1 0 Sap, sulfolipid-1-addressing protein Vac7 PF12751.7 OAP63990.1 - 5.9e-139 463.7 2.5 5.9e-139 463.7 2.5 1.8 2 0 0 2 2 2 1 Vacuolar segregation subunit 7 OMPdecase PF00215.24 OAP63991.1 - 3.9e-69 232.7 0.0 4.5e-69 232.5 0.0 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Pkinase PF00069.25 OAP63992.1 - 2.6e-39 135.2 0.0 1.2e-37 129.7 0.0 2.5 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP63992.1 - 2.4e-23 82.7 0.0 4.3e-23 81.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OAP63992.1 - 0.11 12.4 0.1 0.2 11.5 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Band_7 PF01145.25 OAP63993.1 - 1.9e-17 63.9 0.2 1.9e-17 63.9 0.2 3.3 2 1 0 2 2 2 1 SPFH domain / Band 7 family SNAD2 PF18745.1 OAP63993.1 - 0.18 11.5 1.9 0.35 10.5 1.6 1.7 1 1 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 2 TBCA PF02970.16 OAP63996.1 - 1.3e-23 83.1 9.0 1.3e-23 83.1 9.0 1.3 1 1 0 1 1 1 1 Tubulin binding cofactor A NYD-SP28 PF14772.6 OAP63996.1 - 0.012 15.6 6.3 0.018 15.1 6.3 1.4 1 1 0 1 1 1 0 Sperm tail FlgN PF05130.12 OAP63996.1 - 0.033 14.7 6.6 0.044 14.3 6.6 1.2 1 0 0 1 1 1 0 FlgN protein Bacillus_HBL PF05791.11 OAP63996.1 - 0.036 13.9 2.1 0.052 13.4 2.1 1.2 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) Phyto_Pns9_10 PF05878.11 OAP63996.1 - 0.038 13.2 0.2 0.043 13.0 0.2 1.0 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns9/Pns10 PCRF PF03462.18 OAP63996.1 - 0.04 13.8 5.6 0.047 13.6 5.6 1.1 1 0 0 1 1 1 0 PCRF domain Med9 PF07544.13 OAP63996.1 - 0.042 13.9 1.2 0.042 13.9 1.2 2.3 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF1910 PF08928.10 OAP63996.1 - 0.66 10.0 4.4 0.75 9.8 3.7 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF1910) DUF4404 PF14357.6 OAP63996.1 - 2 9.1 7.0 0.39 11.4 1.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) THOC7 PF05615.13 OAP63997.1 - 4.3e-36 124.1 5.3 4.3e-36 124.1 5.3 2.2 1 1 1 2 2 2 1 Tho complex subunit 7 KASH_CCD PF14662.6 OAP63997.1 - 0.002 18.0 6.2 0.0033 17.3 6.2 1.4 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH FAM76 PF16046.5 OAP63997.1 - 0.21 10.9 1.9 0.32 10.3 1.9 1.3 1 0 0 1 1 1 0 FAM76 protein Spc7 PF08317.11 OAP63997.1 - 0.23 10.3 10.1 0.37 9.6 10.1 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4407 PF14362.6 OAP63997.1 - 0.45 9.8 10.8 0.67 9.3 10.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) YabA PF06156.13 OAP63997.1 - 0.51 11.0 5.2 0.29 11.8 1.0 2.2 1 1 0 2 2 2 0 Initiation control protein YabA UPF0242 PF06785.11 OAP63997.1 - 1.1 9.3 6.7 1.7 8.7 6.7 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Spc24 PF08286.11 OAP63997.1 - 8.5 6.7 8.4 15 5.9 1.2 2.4 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Elongin_A PF06881.11 OAP63998.1 - 5.4e-31 107.2 0.9 5.4e-31 107.2 0.9 1.9 2 0 0 2 2 2 1 RNA polymerase II transcription factor SIII (Elongin) subunit A Nucleo_P87 PF07267.11 OAP63998.1 - 0.0013 17.7 4.3 0.0021 17.0 4.3 1.2 1 0 0 1 1 1 1 Nucleopolyhedrovirus capsid protein P87 NOA36 PF06524.12 OAP63998.1 - 2.4 7.4 4.4 4.7 6.5 4.4 1.5 1 0 0 1 1 1 0 NOA36 protein Mcp5_PH PF12814.7 OAP63999.1 - 7.6e-47 158.4 0.5 1.4e-46 157.5 0.5 1.5 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology Fez1 PF06818.15 OAP63999.1 - 0.00022 21.7 12.2 0.00042 20.8 12.2 1.3 1 0 0 1 1 1 1 Fez1 TPR_MLP1_2 PF07926.12 OAP63999.1 - 0.022 14.8 20.1 0.08 13.0 8.4 2.3 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Peptidase_C4 PF00863.19 OAP63999.1 - 0.15 11.4 0.1 0.41 9.9 0.0 1.6 2 0 0 2 2 2 0 Peptidase family C4 ADIP PF11559.8 OAP63999.1 - 0.16 12.1 15.6 0.025 14.7 3.4 2.3 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF4407 PF14362.6 OAP63999.1 - 2.8 7.2 7.3 4.3 6.6 7.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SlyX PF04102.12 OAP63999.1 - 4.1 8.1 10.7 0.64 10.7 4.0 2.7 1 1 1 2 2 2 0 SlyX Lebercilin PF15619.6 OAP63999.1 - 5.4 6.6 19.1 9.6 5.8 19.1 1.3 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Jnk-SapK_ap_N PF09744.9 OAP63999.1 - 8.2 6.6 14.3 0.25 11.6 4.3 2.3 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 HAD_2 PF13419.6 OAP64000.1 - 1.8e-09 37.9 0.0 2.4e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OAP64000.1 - 2.8e-09 37.6 0.0 3.7e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OAP64000.1 - 0.00037 20.5 0.0 0.00075 19.5 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HTH_AraC PF00165.23 OAP64000.1 - 0.023 14.8 0.0 0.055 13.6 0.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix proteins, AraC family GST_N_2 PF13409.6 OAP64001.1 - 1.6e-19 69.9 0.0 3e-19 69.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAP64001.1 - 3e-14 52.8 0.0 6.3e-14 51.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OAP64001.1 - 2.1e-06 27.9 0.1 4.2e-06 26.9 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OAP64001.1 - 0.0001 22.4 0.1 0.00027 21.1 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 OAP64001.1 - 0.0023 18.3 0.0 0.024 15.1 0.0 2.2 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Ras PF00071.22 OAP64002.1 - 1.1e-52 177.9 0.2 1.4e-51 174.3 0.2 2.0 1 1 0 1 1 1 1 Ras family Roc PF08477.13 OAP64002.1 - 1.3e-18 67.4 0.0 1.6e-17 63.8 0.0 2.2 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAP64002.1 - 0.00092 18.7 0.0 0.0018 17.7 0.1 1.5 2 0 0 2 2 2 1 ADP-ribosylation factor family Septin PF00735.18 OAP64002.1 - 0.083 12.2 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Septin AAA_25 PF13481.6 OAP64002.1 - 0.18 11.4 0.0 0.32 10.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain CbiA PF01656.23 OAP64002.1 - 0.19 11.8 0.1 0.55 10.3 0.1 1.8 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain zf-GRF PF06839.12 OAP64003.1 - 0.003 17.6 5.5 0.0059 16.7 5.5 1.5 1 0 0 1 1 1 1 GRF zinc finger PKcGMP_CC PF16808.5 OAP64003.1 - 0.009 15.8 0.3 0.019 14.8 0.3 1.5 1 0 0 1 1 1 1 Coiled-coil N-terminus of cGMP-dependent protein kinase DivIC PF04977.15 OAP64003.1 - 0.07 12.9 1.1 0.15 11.9 1.1 1.4 1 0 0 1 1 1 0 Septum formation initiator Kinesin PF00225.23 OAP64004.1 - 4.5e-112 374.3 0.0 7.1e-112 373.6 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain DUF3694 PF12473.8 OAP64004.1 - 5.5e-39 134.3 0.0 1.4e-38 133.0 0.0 1.8 1 0 0 1 1 1 1 Kinesin protein Kinesin_assoc PF16183.5 OAP64004.1 - 9.3e-39 133.4 9.4 9.3e-32 110.6 0.1 3.1 2 1 1 3 3 3 2 Kinesin-associated Microtub_bd PF16796.5 OAP64004.1 - 4.8e-25 88.2 0.0 1.4e-24 86.7 0.0 1.9 1 0 0 1 1 1 1 Microtubule binding FHA PF00498.26 OAP64004.1 - 3.5e-05 24.1 2.7 7.2e-05 23.1 0.2 3.0 4 0 0 4 4 4 1 FHA domain Yop-YscD_cpl PF16697.5 OAP64004.1 - 9.5e-05 22.7 0.0 0.00032 21.0 0.0 1.9 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain KIF1B PF12423.8 OAP64004.1 - 0.00043 20.7 1.1 0.0013 19.1 1.1 1.9 1 0 0 1 1 1 1 Kinesin protein 1B PH PF00169.29 OAP64004.1 - 0.079 13.5 0.0 0.27 11.8 0.0 2.0 1 0 0 1 1 1 0 PH domain UPF0242 PF06785.11 OAP64004.1 - 0.79 9.8 12.7 1.1 9.3 2.6 2.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus NAM-associated PF14303.6 OAP64004.1 - 2.6 8.8 9.5 0.1 13.3 2.0 2.4 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain Macoilin PF09726.9 OAP64004.1 - 6 5.3 16.1 0.032 12.8 6.0 2.0 2 0 0 2 2 2 0 Macoilin family MIP PF00230.20 OAP64005.1 - 3.1e-46 157.9 15.0 3.8e-46 157.6 15.0 1.0 1 0 0 1 1 1 1 Major intrinsic protein RasGEF PF00617.19 OAP64006.1 - 2.6e-43 148.3 0.2 5.3e-43 147.3 0.0 1.7 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 OAP64006.1 - 6.6e-11 42.4 0.0 2.5e-10 40.6 0.0 2.0 1 0 0 1 1 1 1 RasGEF N-terminal motif Ras PF00071.22 OAP64006.1 - 7e-07 29.0 0.0 2.2e-06 27.4 0.0 1.8 1 1 0 1 1 1 1 Ras family Arf PF00025.21 OAP64006.1 - 0.00037 20.0 0.0 0.00063 19.2 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 OAP64006.1 - 0.011 15.0 0.0 0.023 13.8 0.0 1.5 1 0 0 1 1 1 0 G-protein alpha subunit Nfu_N PF08712.11 OAP64008.1 - 8.6e-30 102.6 0.0 3.6e-29 100.6 0.0 1.9 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 OAP64008.1 - 2.7e-27 94.7 0.1 4.3e-27 94.1 0.1 1.3 1 0 0 1 1 1 1 NifU-like domain PSP1 PF04468.12 OAP64009.1 - 3.2e-28 97.8 3.8 5.7e-28 97.0 3.8 1.4 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Thiolase_N PF00108.23 OAP64010.1 - 0.067 12.5 0.2 12 5.2 0.1 3.0 3 0 0 3 3 3 0 Thiolase, N-terminal domain Ribosomal_L15e PF00827.17 OAP64011.1 - 6e-90 300.1 8.9 8.2e-90 299.7 8.9 1.1 1 0 0 1 1 1 1 Ribosomal L15 zf-CSL PF05207.13 OAP64012.1 - 9e-22 76.6 0.4 1.2e-21 76.1 0.4 1.2 1 0 0 1 1 1 1 CSL zinc finger Prok-RING_1 PF14446.6 OAP64012.1 - 0.12 12.3 1.1 0.25 11.3 1.1 1.5 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 Terminase_GpA PF05876.12 OAP64012.1 - 0.14 10.6 0.0 0.15 10.6 0.0 1.1 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) AKAP7_NLS PF10469.9 OAP64013.1 - 7.6e-17 61.9 0.0 4.4e-08 33.3 0.0 2.5 2 1 0 2 2 2 2 AKAP7 2'5' RNA ligase-like domain LigT_PEase PF02834.16 OAP64013.1 - 0.00074 19.7 0.6 3.3 8.0 0.0 3.6 3 0 0 3 3 3 2 LigT like Phosphoesterase 2_5_RNA_ligase2 PF13563.6 OAP64013.1 - 0.0027 17.7 0.2 0.019 14.9 0.0 2.1 2 0 0 2 2 2 1 2'-5' RNA ligase superfamily Lipoprotein_16 PF03923.13 OAP64014.1 - 0.24 11.0 0.0 0.69 9.6 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized lipoprotein AdoHcyase PF05221.17 OAP64015.1 - 1.7e-128 428.0 0.0 7.7e-73 245.2 0.1 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 OAP64015.1 - 1.6e-83 278.7 4.7 2.6e-83 278.0 4.7 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 OAP64015.1 - 2.6e-07 30.2 0.2 5e-07 29.3 0.2 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 OAP64015.1 - 0.0024 18.1 0.1 0.0061 16.8 0.1 1.7 1 0 0 1 1 1 1 TrkA-N domain IlvN PF07991.12 OAP64015.1 - 0.0039 16.8 0.3 0.0069 16.0 0.3 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain ELFV_dehydrog PF00208.21 OAP64015.1 - 0.019 14.7 0.6 0.036 13.8 0.5 1.5 1 1 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase OSCP PF00213.18 OAP64017.1 - 3.3e-47 160.8 1.3 3.8e-47 160.6 1.3 1.0 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit DUF5336 PF17270.2 OAP64018.1 - 0.42 10.2 4.1 0.51 10.0 0.3 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5336) Ost5 PF05251.12 OAP64018.1 - 3.4 8.0 7.2 11 6.4 0.1 3.6 4 0 0 4 4 4 0 Oligosaccharyltransferase subunit 5 Glyco_hydro_63 PF03200.16 OAP64019.1 - 1.9e-07 30.2 10.7 3.4e-06 26.1 1.1 4.2 4 1 0 4 4 4 2 Glycosyl hydrolase family 63 C-terminal domain TTSSLRR PF12468.8 OAP64019.1 - 0.038 14.2 0.5 0.14 12.4 0.5 2.1 1 1 0 1 1 1 0 Type III secretion system leucine rich repeat protein SNF2_N PF00176.23 OAP64020.1 - 1.1e-65 221.7 0.1 1.9e-65 220.9 0.0 1.4 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OAP64020.1 - 2.6e-11 43.9 0.0 1.2e-10 41.7 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 OAP64020.1 - 2.1e-07 30.9 0.0 1.8e-06 27.8 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 OAP64020.1 - 5.2e-07 29.8 0.1 2.5e-05 24.4 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Prok-RING_4 PF14447.6 OAP64020.1 - 0.00016 21.5 2.1 0.00016 21.5 2.1 1.7 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 OAP64020.1 - 0.0033 17.4 5.2 0.0066 16.4 5.2 1.6 1 0 0 1 1 1 1 zinc-RING finger domain Sgf11 PF08209.11 OAP64020.1 - 0.14 11.8 1.8 12 5.6 0.1 2.5 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) zf-C3HC4_3 PF13920.6 OAP64020.1 - 1.7 8.6 4.8 0.57 10.1 1.3 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Aldo_ket_red PF00248.21 OAP64022.1 - 1.1e-35 123.3 0.0 2.5e-33 115.5 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family bZIP_1 PF00170.21 OAP64023.1 - 2.7e-09 37.0 9.5 5.2e-09 36.1 9.5 1.4 1 0 0 1 1 1 1 bZIP transcription factor PAP1 PF08601.10 OAP64023.1 - 1.9e-07 31.2 0.0 1.9e-07 31.2 0.0 2.3 2 1 0 2 2 2 1 Transcription factor PAP1 bZIP_Maf PF03131.17 OAP64023.1 - 2.1e-06 28.2 3.8 3.2e-06 27.6 3.8 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor SHE3 PF17078.5 OAP64023.1 - 0.0074 16.0 2.3 0.01 15.6 2.3 1.1 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 DUF2514 PF10721.9 OAP64023.1 - 0.0087 16.1 5.0 0.015 15.3 5.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2514) bZIP_2 PF07716.15 OAP64023.1 - 0.016 15.3 12.4 0.027 14.6 11.8 1.6 1 1 0 1 1 1 0 Basic region leucine zipper DUF3549 PF12069.8 OAP64023.1 - 0.023 13.8 0.8 0.033 13.2 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3549) TMF_TATA_bd PF12325.8 OAP64023.1 - 0.03 14.6 3.7 0.054 13.7 3.7 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding V_ATPase_I PF01496.19 OAP64023.1 - 0.045 11.7 1.5 0.059 11.3 1.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GvpL_GvpF PF06386.11 OAP64023.1 - 0.1 12.5 3.2 0.15 11.9 3.2 1.2 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF YabA PF06156.13 OAP64023.1 - 0.18 12.5 0.5 0.32 11.6 0.5 1.5 1 0 0 1 1 1 0 Initiation control protein YabA NRBF2 PF08961.10 OAP64023.1 - 0.25 10.9 5.3 0.34 10.5 5.1 1.3 1 1 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator ADIP PF11559.8 OAP64023.1 - 0.31 11.1 8.8 0.52 10.4 8.8 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding APG6_N PF17675.1 OAP64023.1 - 1.2 9.7 7.7 1.8 9.1 7.7 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region Phosducin PF02114.16 OAP64024.1 - 1.2e-11 44.1 0.1 2.3e-11 43.1 0.1 1.3 1 1 0 1 1 1 1 Phosducin PBP1_TM PF14812.6 OAP64024.1 - 0.34 11.3 17.5 3.5 8.1 0.3 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.10 OAP64024.1 - 0.42 11.0 9.7 2.4 8.6 4.1 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Adaptin_N PF01602.20 OAP64025.1 - 4.5e-115 385.2 0.1 6.2e-115 384.7 0.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 OAP64025.1 - 9.1e-55 184.9 2.0 1.8e-54 184.0 2.0 1.5 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 OAP64025.1 - 1.8e-27 95.8 0.0 6.8e-27 93.9 0.0 2.0 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 OAP64025.1 - 1.2e-19 70.4 2.4 2.5e-12 47.0 0.0 5.7 4 1 2 6 6 6 3 HEAT repeats Cnd1 PF12717.7 OAP64025.1 - 1.4e-09 38.2 7.3 0.0065 16.5 0.1 4.8 4 1 0 4 4 4 3 non-SMC mitotic condensation complex subunit 1 HEAT_PBS PF03130.16 OAP64025.1 - 0.006 17.2 0.3 5.9 7.9 0.0 4.0 3 0 0 3 3 3 1 PBS lyase HEAT-like repeat HEAT PF02985.22 OAP64025.1 - 0.006 16.7 9.6 0.34 11.3 0.1 5.8 7 0 0 7 7 7 1 HEAT repeat HEAT_EZ PF13513.6 OAP64025.1 - 0.018 15.5 0.4 0.098 13.2 0.4 2.3 1 0 0 1 1 1 0 HEAT-like repeat RTP1_C1 PF10363.9 OAP64025.1 - 0.049 13.8 0.7 9.5 6.5 0.0 3.6 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 CLASP_N PF12348.8 OAP64025.1 - 0.05 13.2 1.3 1.9 8.0 0.1 3.0 3 0 0 3 3 3 0 CLASP N terminal Arm PF00514.23 OAP64025.1 - 0.11 12.5 0.0 28 4.9 0.0 4.0 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat SPC25 PF06703.11 OAP64026.1 - 2.6e-52 176.9 0.1 3.4e-52 176.5 0.1 1.2 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) Fungal_trans PF04082.18 OAP64027.1 - 1.5e-27 96.3 0.2 2e-27 95.9 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP64027.1 - 6.4e-08 32.6 9.8 1.3e-07 31.6 9.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amdase PF17645.1 OAP64028.1 - 6e-14 52.2 0.0 7.2e-14 51.9 0.0 1.1 1 0 0 1 1 1 1 Arylmalonate decarboxylase Transp_cyt_pur PF02133.15 OAP64029.1 - 6.3e-89 298.8 38.2 7.4e-89 298.5 38.2 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Aldo_ket_red PF00248.21 OAP64030.1 - 1e-45 156.2 0.0 1.2e-45 156.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family PAF-AH_p_II PF03403.13 OAP64032.1 - 1.4e-12 46.8 0.0 4.4e-06 25.5 0.1 2.4 2 1 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Hydrolase_4 PF12146.8 OAP64032.1 - 0.0013 18.0 0.0 0.11 11.8 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 OAP64032.1 - 0.0031 16.5 0.9 0.025 13.5 0.4 2.4 2 1 0 2 2 2 1 Chlorophyllase enzyme Peptidase_S28 PF05577.12 OAP64033.1 - 1.7e-40 139.2 0.5 2e-40 138.9 0.5 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Hydrolase_4 PF12146.8 OAP64033.1 - 4.3e-06 26.2 0.0 7.2e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 OAP64033.1 - 2.8e-05 23.7 0.1 5e-05 22.9 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S37 PF05576.11 OAP64033.1 - 0.00082 18.2 0.1 0.0012 17.6 0.1 1.2 1 0 0 1 1 1 1 PS-10 peptidase S37 Fungal_trans_2 PF11951.8 OAP64034.1 - 0.025 13.4 0.9 0.11 11.3 0.9 1.8 1 1 0 1 1 1 0 Fungal specific transcription factor domain Beta-lactamase PF00144.24 OAP64035.1 - 3e-49 168.1 0.0 3.9e-49 167.7 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Beta-lactamase2 PF13354.6 OAP64035.1 - 0.0046 16.6 0.0 0.02 14.5 0.0 1.9 2 0 0 2 2 2 1 Beta-lactamase enzyme family Peptidase_S11 PF00768.20 OAP64035.1 - 0.097 12.1 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase GFA PF04828.14 OAP64036.1 - 1.8e-21 76.3 0.1 2.3e-21 75.9 0.1 1.1 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme TFR_dimer PF04253.15 OAP64037.1 - 9.1e-31 106.5 0.1 1.5e-30 105.8 0.1 1.3 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 OAP64037.1 - 3.1e-22 79.2 0.0 5e-22 78.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 OAP64037.1 - 6.9e-09 35.6 0.0 2.2e-08 34.0 0.0 1.9 1 1 0 1 1 1 1 PA domain Nicastrin PF05450.15 OAP64037.1 - 0.0085 15.6 0.0 0.018 14.5 0.0 1.4 1 0 0 1 1 1 1 Nicastrin NMO PF03060.15 OAP64038.1 - 1.3e-29 103.6 16.2 2.4e-23 83.1 7.6 2.8 1 1 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.18 OAP64038.1 - 1.6e-07 30.7 1.0 1.9e-07 30.5 1.0 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 OAP64038.1 - 3.6e-05 22.9 7.2 0.00016 20.8 7.2 1.9 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 OAP64038.1 - 0.00043 19.5 1.8 0.00074 18.8 1.8 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.21 OAP64038.1 - 0.036 13.5 1.5 0.11 11.9 0.1 2.3 3 0 0 3 3 3 0 Histidine biosynthesis protein DUF561 PF04481.12 OAP64038.1 - 0.19 10.9 1.4 0.33 10.1 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF561) MFS_1 PF07690.16 OAP64039.1 - 1.9e-38 132.3 15.7 2.1e-25 89.4 4.8 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAP64039.1 - 1.7e-11 43.7 6.2 1.6e-10 40.4 0.3 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 OAP64039.1 - 0.00024 19.7 0.2 0.00024 19.7 0.2 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) CDC45 PF02724.14 OAP64039.1 - 0.36 9.1 5.4 0.52 8.5 5.4 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 OAP64039.1 - 0.47 9.8 5.3 0.67 9.3 5.3 1.1 1 0 0 1 1 1 0 SDA1 FAM176 PF14851.6 OAP64039.1 - 0.49 10.0 0.0 0.49 10.0 0.0 1.9 2 0 0 2 2 2 0 FAM176 family DUF2457 PF10446.9 OAP64039.1 - 1.8 7.6 9.1 2.4 7.2 9.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) FAD_binding_7 PF03441.14 OAP64040.1 - 4.2e-79 264.7 0.7 4.2e-79 264.7 0.7 1.5 2 0 0 2 2 2 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 OAP64040.1 - 2.1e-38 131.9 0.0 3.7e-38 131.1 0.0 1.3 1 0 0 1 1 1 1 DNA photolyase Viral_env_E26 PF11050.8 OAP64040.1 - 0.0089 15.4 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 1 Virus envelope protein E26 Polyoma_agno PF01736.16 OAP64040.1 - 0.075 12.8 0.1 3.2 7.5 0.0 2.7 3 0 0 3 3 3 0 Polyomavirus agnoprotein HATPase_c PF02518.26 OAP64041.1 - 1.1e-25 90.4 0.0 2.1e-24 86.2 0.0 2.4 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 OAP64041.1 - 4.3e-24 84.8 0.2 8.8e-24 83.8 0.2 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 OAP64041.1 - 3.7e-14 52.5 0.1 1.5e-13 50.5 0.0 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 OAP64041.1 - 0.00066 20.0 0.2 0.062 13.7 0.2 2.8 2 0 0 2 2 2 1 HAMP domain SesA PF17107.5 OAP64042.1 - 0.039 14.1 0.7 0.095 12.9 0.7 1.6 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF520 PF04461.13 OAP64042.1 - 0.06 13.5 0.2 0.14 12.3 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF520) HAMP PF00672.25 OAP64043.1 - 4.5e-41 139.0 22.2 3.4e-08 33.7 0.2 8.4 7 2 1 8 8 7 6 HAMP domain HATPase_c PF02518.26 OAP64043.1 - 3.4e-31 108.0 0.8 1.4e-30 106.1 0.2 2.4 2 0 0 2 2 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 OAP64043.1 - 7e-26 90.6 0.4 3.1e-25 88.5 0.4 2.2 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 OAP64043.1 - 1.2e-17 63.7 2.3 5.7e-17 61.5 0.3 3.4 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain DUF4279 PF14106.6 OAP64043.1 - 5.8e-05 23.3 0.0 14 5.9 0.0 5.4 5 1 0 5 5 4 0 Domain of unknown function (DUF4279) Syntaxin_2 PF14523.6 OAP64043.1 - 0.0054 17.1 21.1 1.3 9.4 0.0 7.4 4 2 2 7 7 7 1 Syntaxin-like protein DUF1843 PF08898.10 OAP64043.1 - 0.01 16.3 3.9 53 4.4 0.0 5.7 5 0 0 5 5 5 0 Domain of unknown function (DUF1843) DUF3829 PF12889.7 OAP64043.1 - 0.016 14.7 17.0 0.9 9.0 0.1 5.6 4 2 2 6 6 6 0 Protein of unknown function (DUF3829) GhoS PF11080.8 OAP64043.1 - 0.026 14.5 4.9 5.6 7.0 0.3 4.2 4 0 0 4 4 4 0 Endoribonuclease GhoS SpoIIID PF12116.8 OAP64043.1 - 0.052 13.7 1.5 73 3.6 0.0 4.8 4 0 0 4 4 4 0 Stage III sporulation protein D CMD PF02627.20 OAP64043.1 - 0.065 13.3 0.6 15 5.8 0.0 3.9 4 0 0 4 4 3 0 Carboxymuconolactone decarboxylase family Helo_like_N PF17111.5 OAP64043.1 - 0.076 12.4 5.0 4.5 6.6 0.1 3.3 3 0 0 3 3 3 0 Fungal N-terminal domain of STAND proteins DUF948 PF06103.11 OAP64043.1 - 0.83 10.0 60.0 1.1 9.6 1.1 11.3 6 2 2 11 11 11 0 Bacterial protein of unknown function (DUF948) Fib_alpha PF08702.10 OAP64043.1 - 2.5 8.3 32.8 0.97 9.6 0.8 7.2 6 1 1 7 7 7 0 Fibrinogen alpha/beta chain family APG6_N PF17675.1 OAP64043.1 - 2.8 8.5 9.5 0.24 11.9 1.9 3.1 4 0 0 4 4 2 0 Apg6 coiled-coil region AdHead_fibreRBD PF16812.5 OAP64043.1 - 5.1 6.9 7.5 0.58 10.0 0.1 3.1 3 0 0 3 3 3 0 C-terminal head domain of the fowl adenovirus type 1 long fibre Tho2 PF11262.8 OAP64043.1 - 5.5 6.1 7.6 0.36 10.0 1.9 1.9 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 Atg14 PF10186.9 OAP64043.1 - 5.9 5.9 7.8 11 5.0 3.5 2.9 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 NAD_binding_7 PF13241.6 OAP64043.1 - 6.7 7.2 6.1 62 4.1 0.1 4.3 3 2 1 4 4 4 0 Putative NAD(P)-binding Fungal_trans PF04082.18 OAP64044.1 - 5.2e-18 65.0 0.1 8.7e-18 64.3 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain CDH-cyt PF16010.5 OAP64045.1 - 6.3e-26 91.2 0.4 1.2e-25 90.3 0.4 1.3 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase Cytochrom_B561 PF03188.16 OAP64045.1 - 8.3e-13 48.7 10.0 1.5e-12 47.8 7.0 2.2 1 1 1 2 2 2 1 Eukaryotic cytochrome b561 DOMON PF03351.17 OAP64045.1 - 0.00025 21.3 0.2 0.00047 20.4 0.2 1.5 1 0 0 1 1 1 1 DOMON domain DUF2427 PF10348.9 OAP64045.1 - 0.0017 18.1 3.0 0.0017 18.1 3.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) DUF202 PF02656.15 OAP64045.1 - 0.0088 16.5 1.9 0.0088 16.5 1.9 3.7 4 0 0 4 4 4 1 Domain of unknown function (DUF202) Borrelia_P13 PF05628.12 OAP64045.1 - 0.032 14.2 2.3 0.077 13.0 2.3 1.6 1 0 0 1 1 1 0 Borrelia membrane protein P13 EphA2_TM PF14575.6 OAP64045.1 - 0.078 13.9 0.0 1.4 9.9 0.0 2.6 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF4083 PF13314.6 OAP64045.1 - 0.17 11.9 0.1 0.7 9.9 0.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) DUF4175 PF13779.6 OAP64045.1 - 0.17 9.8 1.0 0.17 9.7 0.1 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) RCR PF12273.8 OAP64045.1 - 0.19 12.4 0.2 0.19 12.4 0.2 2.3 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red DUF5305 PF17231.2 OAP64045.1 - 0.32 10.4 0.2 14 5.0 0.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5305) Tad PF13400.6 OAP64045.1 - 0.35 11.2 0.1 0.35 11.2 0.1 3.7 4 0 0 4 4 3 0 Putative Flp pilus-assembly TadE/G-like AzlD PF05437.12 OAP64045.1 - 0.87 9.8 10.4 0.047 13.9 2.9 2.5 2 1 0 2 2 2 0 Branched-chain amino acid transport protein (AzlD) DUF1516 PF07457.11 OAP64045.1 - 1.2 9.3 11.1 0.15 12.3 1.3 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1516) PIRT PF15099.6 OAP64045.1 - 2.3 7.8 5.3 4.9 6.7 0.8 2.8 1 1 2 3 3 3 0 Phosphoinositide-interacting protein family Tetraspanin PF00335.20 OAP64045.1 - 4.6 6.9 7.8 1.7 8.3 3.5 2.3 2 1 1 3 3 3 0 Tetraspanin family Sugar_tr PF00083.24 OAP64046.1 - 5.4e-86 289.2 23.7 6.2e-86 289.0 23.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP64046.1 - 5.8e-30 104.4 53.1 1.3e-26 93.4 27.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 OAP64046.1 - 0.00021 19.8 2.0 0.0004 18.9 2.0 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) RNase_PH PF01138.21 OAP64047.1 - 1.4e-28 100.0 0.1 4.9e-28 98.2 0.0 1.8 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 HMG-CoA_red PF00368.18 OAP64048.1 - 2.7e-140 467.6 4.2 3.5e-140 467.2 4.2 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.6 OAP64048.1 - 8.7e-46 155.6 2.1 1.4e-45 154.9 2.1 1.4 1 0 0 1 1 1 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.8 OAP64048.1 - 9e-12 45.1 8.3 8e-10 38.7 8.3 2.6 1 1 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 OAP64048.1 - 0.00011 20.4 3.1 0.00011 20.4 3.1 1.5 2 0 0 2 2 2 1 Patched family DUF3197 PF11432.8 OAP64048.1 - 0.16 11.9 0.0 17 5.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3197) GIT_SHD PF08518.11 OAP64049.1 - 1e-24 85.8 6.2 7.5e-14 51.1 0.6 2.7 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT GIT1_C PF12205.8 OAP64049.1 - 5.4e-07 29.7 0.6 4.7e-06 26.7 0.1 2.6 2 0 0 2 2 2 1 G protein-coupled receptor kinase-interacting protein 1 C term Filament PF00038.21 OAP64049.1 - 0.0087 15.7 19.2 0.035 13.7 2.7 3.1 3 0 0 3 3 3 2 Intermediate filament protein Tropomyosin_1 PF12718.7 OAP64049.1 - 0.01 16.0 20.3 0.27 11.4 2.9 3.0 2 0 0 2 2 2 0 Tropomyosin like YABBY PF04690.13 OAP64049.1 - 0.038 14.5 0.8 0.14 12.7 0.8 2.0 1 0 0 1 1 1 0 YABBY protein Baculo_PEP_C PF04513.12 OAP64049.1 - 0.051 13.6 0.2 0.051 13.6 0.2 3.3 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fez1 PF06818.15 OAP64049.1 - 0.4 11.1 20.5 1.4 9.4 15.6 2.8 3 0 0 3 3 2 0 Fez1 Syntaxin_2 PF14523.6 OAP64049.1 - 0.58 10.5 19.1 0.29 11.5 1.8 4.8 4 1 1 5 5 5 0 Syntaxin-like protein DUF4201 PF13870.6 OAP64049.1 - 0.84 9.3 20.7 0.39 10.4 12.8 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) Prominin PF05478.11 OAP64049.1 - 1.4 6.8 8.7 6.4 4.6 0.0 2.6 2 1 1 3 3 3 0 Prominin DUF2730 PF10805.8 OAP64049.1 - 1.4 9.0 6.2 26 5.0 0.3 3.8 3 1 0 3 3 3 0 Protein of unknown function (DUF2730) GrpE PF01025.19 OAP64049.1 - 1.6 8.4 13.9 4.3 7.0 0.8 3.1 2 0 0 2 2 2 0 GrpE THP2 PF09432.10 OAP64049.1 - 2.2 8.3 11.8 0.21 11.6 0.6 3.1 2 1 1 3 3 3 0 Tho complex subunit THP2 APG6_N PF17675.1 OAP64049.1 - 4.9 7.7 31.8 25 5.4 20.1 3.1 1 1 1 2 2 2 0 Apg6 coiled-coil region HIP1_clath_bdg PF16515.5 OAP64049.1 - 5.8 7.6 26.6 34 5.1 7.5 4.1 3 0 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Spc7 PF08317.11 OAP64049.1 - 6.7 5.5 29.3 0.34 9.8 9.8 3.2 2 1 1 3 3 3 0 Spc7 kinetochore protein Terminase_4 PF05119.12 OAP64049.1 - 6.9 7.2 6.4 47 4.5 0.0 3.8 3 1 0 3 3 3 0 Phage terminase, small subunit BST2 PF16716.5 OAP64049.1 - 7.8 7.2 24.9 1.5 9.4 5.7 3.2 4 0 0 4 4 2 0 Bone marrow stromal antigen 2 DUF2203 PF09969.9 OAP64049.1 - 8.2 7.2 15.7 0.9 10.3 1.7 4.0 4 0 0 4 4 3 0 Uncharacterized conserved protein (DUF2203) FlaC_arch PF05377.11 OAP64049.1 - 9 6.8 19.6 5.8 7.4 1.7 4.8 4 1 0 4 4 4 0 Flagella accessory protein C (FlaC) Pro_isomerase PF00160.21 OAP64050.1 - 4.8e-42 143.9 0.1 6e-42 143.6 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF3176 PF11374.8 OAP64051.1 - 0.0014 18.8 2.8 0.0045 17.2 2.8 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) Cytochrom_B559 PF00283.19 OAP64051.1 - 8.6 5.9 6.8 5.6 6.5 1.7 2.4 2 0 0 2 2 2 0 Cytochrome b559, alpha (gene psbE) and beta (gene psbF)subunits Oxysterol_BP PF01237.18 OAP64052.1 - 2.2e-137 457.9 0.0 1.1e-136 455.6 0.0 2.0 2 0 0 2 2 2 1 Oxysterol-binding protein Ank_5 PF13857.6 OAP64052.1 - 1e-15 57.5 0.7 9.5e-10 38.5 0.2 3.9 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 OAP64052.1 - 5.5e-13 48.7 1.5 0.0038 17.6 0.1 4.9 5 0 0 5 5 5 3 Ankyrin repeat PH PF00169.29 OAP64052.1 - 3e-11 43.7 0.5 7.1e-11 42.6 0.5 1.7 1 0 0 1 1 1 1 PH domain Ank_4 PF13637.6 OAP64052.1 - 3e-10 40.4 0.1 0.00024 21.6 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OAP64052.1 - 3.1e-10 40.5 0.0 1.7e-05 25.3 0.0 2.7 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OAP64052.1 - 3.9e-10 39.1 0.1 0.011 16.2 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat PH_8 PF15409.6 OAP64052.1 - 4.1e-07 30.2 0.5 9.3e-07 29.0 0.5 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 OAP64052.1 - 0.00011 22.6 1.4 0.00011 22.6 1.4 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain PH_17 PF18012.1 OAP64052.1 - 0.1 12.3 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 PH domain ENTH PF01417.20 OAP64053.1 - 8.9e-45 151.8 0.1 1.3e-44 151.2 0.1 1.2 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 OAP64053.1 - 8e-05 21.8 0.0 0.00011 21.3 0.0 1.1 1 0 0 1 1 1 1 ANTH domain DUF5102 PF17104.5 OAP64053.1 - 0.035 14.2 0.5 0.035 14.2 0.5 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF5102) Sugar_tr PF00083.24 OAP64054.1 - 9.8e-77 258.7 26.3 1.1e-76 258.5 26.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP64054.1 - 1.5e-27 96.5 41.4 5.2e-26 91.4 23.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 OAP64054.1 - 1.8e-06 26.8 4.4 1.8e-06 26.8 4.4 3.1 4 0 0 4 4 4 2 MFS/sugar transport protein Transp_cyt_pur PF02133.15 OAP64055.1 - 8.5e-47 159.9 28.6 1e-46 159.6 28.6 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF3087 PF11286.8 OAP64055.1 - 2.2 7.7 7.1 5.8 6.4 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3087) Fungal_trans PF04082.18 OAP64056.1 - 5.8e-07 28.8 0.1 1.3e-06 27.7 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP64056.1 - 0.015 15.4 2.1 0.015 15.4 2.1 3.1 3 1 0 3 3 3 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Mst1_SARAH PF11629.8 OAP64056.1 - 1.4 9.1 3.4 1.3 9.1 1.3 2.1 2 0 0 2 2 2 0 C terminal SARAH domain of Mst1 HET PF06985.11 OAP64059.1 - 8.2e-29 100.8 0.0 5.5e-28 98.1 0.0 2.3 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) RRP7 PF12923.7 OAP64060.1 - 6.5e-30 103.7 10.9 6.5e-30 103.7 10.9 1.5 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain RRM_Rrp7 PF17799.1 OAP64060.1 - 1.4e-27 96.5 0.0 6.4e-27 94.3 0.0 2.0 2 1 0 2 2 2 1 Rrp7 RRM-like N-terminal domain DUF5093 PF17011.5 OAP64060.1 - 0.011 16.0 0.0 0.011 16.0 0.0 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF5093) RRM_1 PF00076.22 OAP64060.1 - 0.069 13.0 0.0 8.5 6.3 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ATP12 PF07542.11 OAP64062.1 - 3.9e-46 156.3 0.3 3.9e-46 156.3 0.3 1.5 2 0 0 2 2 2 1 ATP12 chaperone protein Pmp3 PF01679.17 OAP64063.1 - 1.9e-11 43.9 4.8 2.4e-11 43.6 4.8 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator SH3_1 PF00018.28 OAP64064.1 - 2.6e-11 42.9 0.0 4.6e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 OAP64064.1 - 3.1e-09 36.5 0.5 5.7e-09 35.7 0.0 1.7 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 OAP64064.1 - 4.1e-07 29.6 0.0 7.7e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Ssu72 PF04722.13 OAP64065.1 - 4.2e-81 271.1 0.0 5e-81 270.8 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein NUDIX PF00293.28 OAP64066.1 - 2.5e-07 30.8 0.0 2.2e-06 27.8 0.0 2.3 1 1 0 1 1 1 1 NUDIX domain IMPDH PF00478.25 OAP64067.1 - 1.9e-129 431.6 1.5 2.2e-129 431.4 1.5 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 OAP64067.1 - 4.4e-19 68.7 0.0 6.9e-10 39.2 0.0 2.6 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.18 OAP64067.1 - 1e-07 31.4 0.7 1e-06 28.0 0.5 2.1 2 0 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.15 OAP64067.1 - 1e-06 28.4 6.2 0.014 14.8 6.3 2.6 2 1 0 2 2 2 2 Nitronate monooxygenase His_biosynth PF00977.21 OAP64067.1 - 0.00022 20.8 2.4 0.001 18.6 2.4 1.9 1 1 0 1 1 1 1 Histidine biosynthesis protein YpsA PF06908.11 OAP64067.1 - 0.034 14.1 0.0 0.063 13.3 0.0 1.3 1 0 0 1 1 1 0 YspA SLOG family Aldolase PF01081.19 OAP64067.1 - 0.04 13.3 0.5 0.15 11.5 0.4 2.0 1 1 0 1 1 1 0 KDPG and KHG aldolase ThiG PF05690.14 OAP64067.1 - 0.06 12.7 1.9 0.093 12.0 1.1 1.7 1 1 0 1 1 1 0 Thiazole biosynthesis protein ThiG PK PF00224.21 OAP64067.1 - 0.076 11.9 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Pyruvate kinase, barrel domain RasGAP_C PF03836.15 OAP64068.1 - 1.2e-48 164.7 5.2 1.2e-48 164.7 5.2 3.8 4 0 0 4 4 4 1 RasGAP C-terminus RasGAP PF00616.19 OAP64068.1 - 7.2e-48 163.1 3.8 2.2e-47 161.5 0.0 3.1 3 0 0 3 3 3 1 GTPase-activator protein for Ras-like GTPase CH PF00307.31 OAP64068.1 - 3e-12 46.7 0.1 1.4e-11 44.5 0.0 2.2 2 0 0 2 2 2 1 Calponin homology (CH) domain Ead_Ea22 PF13935.6 OAP64068.1 - 0.009 16.7 5.5 0.36 11.5 0.7 2.9 2 0 0 2 2 2 2 Ead/Ea22-like protein CAMSAP_CH PF11971.8 OAP64068.1 - 0.013 15.3 0.0 0.056 13.3 0.0 2.1 1 0 0 1 1 1 0 CAMSAP CH domain IQ PF00612.27 OAP64068.1 - 0.037 13.8 64.3 0.48 10.3 0.0 14.0 16 0 0 16 16 16 0 IQ calmodulin-binding motif Rx_N PF18052.1 OAP64068.1 - 3.7 7.9 7.2 2.7 8.3 1.3 3.6 2 1 0 2 2 2 0 Rx N-terminal domain Pkinase PF00069.25 OAP64070.1 - 4.9e-75 252.3 0.0 7.8e-75 251.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP64070.1 - 4.3e-36 124.5 0.0 1e-35 123.3 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAP64070.1 - 4.6e-05 22.9 1.2 2.7 7.2 0.1 3.3 3 0 0 3 3 3 3 Kinase-like APH PF01636.23 OAP64070.1 - 0.0026 17.7 0.0 0.38 10.6 0.0 2.9 2 1 1 3 3 3 2 Phosphotransferase enzyme family DUF3501 PF12007.8 OAP64070.1 - 0.029 14.4 0.1 0.053 13.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3501) Pkinase_fungal PF17667.1 OAP64070.1 - 0.077 11.8 0.6 0.25 10.1 0.0 2.0 3 0 0 3 3 3 0 Fungal protein kinase MFS_1 PF07690.16 OAP64071.1 - 7.8e-35 120.4 45.4 7.8e-35 120.4 45.4 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAP64071.1 - 2.5e-10 39.8 40.7 6.7e-06 25.2 15.6 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter HET PF06985.11 OAP64072.1 - 1.5e-28 100.0 0.0 3.5e-28 98.8 0.0 1.6 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) IDO PF01231.18 OAP64073.1 - 9.9e-30 103.7 0.0 1.3e-29 103.3 0.0 1.1 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase zf-C2H2_7 PF15269.6 OAP64074.1 - 0.0023 18.0 0.4 0.0044 17.1 0.4 1.4 1 0 0 1 1 1 1 Zinc-finger zf-H2C2_5 PF13909.6 OAP64074.1 - 0.0026 17.5 3.1 0.0046 16.7 3.1 1.4 1 0 0 1 1 1 1 C2H2-type zinc-finger domain DJ-1_PfpI PF01965.24 OAP64075.1 - 8.2e-09 35.5 0.0 1.2e-08 35.0 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family CDC37_M PF08565.11 OAP64077.1 - 0.00022 21.1 0.0 0.00035 20.5 0.0 1.3 1 0 0 1 1 1 1 Cdc37 Hsp90 binding domain DUF4897 PF16238.5 OAP64077.1 - 0.085 12.7 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4897) TMF_TATA_bd PF12325.8 OAP64078.1 - 0.012 15.8 0.6 19 5.5 0.0 3.5 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding Cucumo_2B PF03263.13 OAP64078.1 - 0.064 13.7 0.2 0.18 12.3 0.1 1.8 2 0 0 2 2 2 0 Cucumovirus protein 2B EzrA PF06160.12 OAP64078.1 - 0.32 9.1 1.6 0.38 8.9 0.3 1.7 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA Cnn_1N PF07989.11 OAP64078.1 - 1.2 9.3 4.3 2.2 8.5 0.2 3.1 3 0 0 3 3 3 0 Centrosomin N-terminal motif 1 CDC37_M PF08565.11 OAP64081.1 - 0.0042 17.0 0.2 0.011 15.6 0.2 1.7 1 1 0 1 1 1 1 Cdc37 Hsp90 binding domain Alpha_adaptinC2 PF02883.20 OAP64081.1 - 0.018 15.4 5.2 1.1 9.5 0.4 2.5 2 0 0 2 2 2 0 Adaptin C-terminal domain DUF883 PF05957.13 OAP64081.1 - 0.028 15.0 1.8 0.028 15.0 1.8 1.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) SLATT_4 PF18186.1 OAP64081.1 - 0.1 12.2 1.2 0.18 11.4 1.2 1.3 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 4 DUF948 PF06103.11 OAP64082.1 - 0.14 12.4 0.1 0.28 11.5 0.1 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) PHD PF00628.29 OAP64083.1 - 2.9e-08 33.5 10.3 2.9e-08 33.5 10.3 2.7 2 1 0 2 2 2 1 PHD-finger zf-RING_2 PF13639.6 OAP64083.1 - 4.4e-08 33.3 1.8 4.4e-08 33.3 1.8 3.6 3 1 0 3 3 3 1 Ring finger domain zf-rbx1 PF12678.7 OAP64083.1 - 3.3e-07 30.5 8.0 8e-07 29.3 1.0 2.6 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 OAP64083.1 - 1.7e-05 24.6 1.8 1.7e-05 24.6 1.8 3.2 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAP64083.1 - 5.5e-05 23.0 0.5 5.5e-05 23.0 0.5 3.1 3 1 1 4 4 3 1 zinc-RING finger domain Prok-RING_4 PF14447.6 OAP64083.1 - 0.00015 21.5 1.5 0.00015 21.5 1.5 3.1 2 1 1 3 3 3 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 OAP64083.1 - 0.00017 21.4 1.0 0.00017 21.4 1.0 3.0 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OAP64083.1 - 0.0011 18.8 1.0 0.0011 18.8 1.0 3.6 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) C1_2 PF03107.16 OAP64083.1 - 0.0059 16.9 1.7 0.0059 16.9 1.7 3.0 4 0 0 4 4 3 1 C1 domain zf-ANAPC11 PF12861.7 OAP64083.1 - 0.009 16.0 0.3 0.009 16.0 0.3 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 OAP64083.1 - 0.029 14.4 1.4 0.029 14.4 1.4 3.3 2 2 1 3 3 3 0 RING-type zinc-finger PHD_2 PF13831.6 OAP64083.1 - 0.063 12.8 5.8 0.18 11.4 5.8 1.8 1 0 0 1 1 1 0 PHD-finger Rtf2 PF04641.12 OAP64083.1 - 0.17 11.2 0.5 2.9 7.2 0.0 2.3 2 0 0 2 2 2 0 Rtf2 RING-finger DZR PF12773.7 OAP64083.1 - 0.38 10.8 8.5 50 4.0 8.5 2.8 1 1 0 1 1 1 0 Double zinc ribbon zf-PHD-like PF15446.6 OAP64083.1 - 0.38 10.4 5.7 0.1 12.2 1.8 2.0 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain Zn_ribbon_17 PF17120.5 OAP64083.1 - 1.2 8.8 11.8 0.28 10.8 1.1 2.4 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-P11 PF03854.14 OAP64083.1 - 2.9 7.6 6.5 0.32 10.7 1.1 2.1 2 0 0 2 2 2 0 P-11 zinc finger Ribosomal_L37ae PF01780.19 OAP64084.1 - 1e-40 137.7 11.1 1.1e-40 137.6 11.1 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family zf-RING_13 PF17977.1 OAP64084.1 - 0.00094 19.3 2.0 0.0013 18.8 2.0 1.2 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Zn_Tnp_IS1595 PF12760.7 OAP64084.1 - 0.011 15.6 2.0 0.019 14.9 2.0 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain DUF1451 PF07295.11 OAP64084.1 - 0.017 15.2 0.9 0.023 14.7 0.9 1.2 1 0 0 1 1 1 0 Zinc-ribbon containing domain A2L_zn_ribbon PF08792.10 OAP64084.1 - 0.058 13.1 4.0 1.9 8.3 0.1 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-BED PF02892.15 OAP64084.1 - 0.27 11.3 6.2 1.3 9.2 0.5 2.2 1 1 1 2 2 2 0 BED zinc finger Sacchrp_dh_NADP PF03435.18 OAP64085.1 - 3.4e-18 66.2 0.0 5.7e-18 65.4 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 OAP64085.1 - 0.03 14.7 0.0 0.066 13.7 0.0 1.6 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain COG5 PF10392.9 OAP64086.1 - 0.0091 16.2 2.7 0.094 12.9 0.7 2.5 2 0 0 2 2 2 2 Golgi transport complex subunit 5 CAF1 PF04857.20 OAP64087.1 - 2.4e-74 250.4 0.0 4.3e-74 249.5 0.0 1.4 1 0 0 1 1 1 1 CAF1 family ribonuclease DNA_pol_A_exo1 PF01612.20 OAP64087.1 - 0.066 12.9 0.0 0.3 10.8 0.0 2.0 2 0 0 2 2 2 0 3'-5' exonuclease SRP_TPR_like PF17004.5 OAP64088.1 - 1.5e-17 63.7 1.4 3.3e-17 62.6 1.4 1.6 1 0 0 1 1 1 1 Putative TPR-like repeat SRP72 PF08492.12 OAP64088.1 - 4.9e-15 55.7 6.3 4.9e-15 55.7 6.3 2.2 2 0 0 2 2 2 1 SRP72 RNA-binding domain TPR_19 PF14559.6 OAP64088.1 - 8.6e-06 26.2 15.2 0.058 13.9 0.0 5.6 6 1 1 7 7 7 2 Tetratricopeptide repeat ANAPC3 PF12895.7 OAP64088.1 - 0.00073 19.7 4.2 1.1 9.5 0.4 4.3 4 0 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.14 OAP64088.1 - 0.0055 17.2 0.8 18 6.3 0.2 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 OAP64088.1 - 0.0079 16.2 9.8 4.7 7.6 0.4 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 OAP64088.1 - 0.014 16.2 6.5 65 4.7 0.9 5.8 5 1 1 6 6 6 0 Tetratricopeptide repeat SPO22 PF08631.10 OAP64088.1 - 0.03 13.8 0.8 1.6 8.1 0.1 3.2 3 0 0 3 3 3 0 Meiosis protein SPO22/ZIP4 like DsrC PF04358.13 OAP64088.1 - 0.058 13.9 0.1 0.25 11.8 0.1 2.1 2 0 0 2 2 2 0 DsrC like protein TPR_10 PF13374.6 OAP64088.1 - 0.065 13.1 5.5 15 5.6 0.3 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 OAP64088.1 - 0.27 11.9 7.0 0.33 11.6 2.0 3.7 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 OAP64088.1 - 1.8 8.5 4.8 40 4.3 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF1349 PF07081.11 OAP64089.1 - 2.3e-19 69.8 0.0 3.1e-19 69.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) F-box PF00646.33 OAP64090.1 - 3.7e-07 29.8 1.7 1e-06 28.5 1.7 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 OAP64090.1 - 0.00011 22.0 0.3 0.00025 20.8 0.3 1.7 1 0 0 1 1 1 1 F-box-like TPR_14 PF13428.6 OAP64090.1 - 0.00064 20.3 1.1 0.035 14.9 0.3 3.4 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 OAP64090.1 - 0.0013 18.7 0.2 0.4 10.9 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 OAP64090.1 - 0.0029 17.7 0.3 0.017 15.3 0.1 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 OAP64090.1 - 0.055 14.1 0.4 0.45 11.2 0.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 OAP64090.1 - 0.093 12.6 0.3 0.41 10.6 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat COX5A PF02284.16 OAP64090.1 - 0.3 11.1 1.6 6.1 6.9 0.0 3.2 3 0 0 3 3 3 0 Cytochrome c oxidase subunit Va ADIP PF11559.8 OAP64091.1 - 5.7e-34 117.4 10.4 5.7e-34 117.4 10.4 2.1 2 0 0 2 2 2 1 Afadin- and alpha -actinin-Binding GrpE PF01025.19 OAP64091.1 - 0.18 11.5 8.5 4 7.1 5.5 2.7 2 1 0 2 2 2 0 GrpE DUF724 PF05266.14 OAP64091.1 - 0.54 10.1 10.4 0.08 12.8 5.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF724) RasGAP_C PF03836.15 OAP64091.1 - 0.91 9.7 7.4 30 4.7 7.4 2.6 1 1 0 1 1 1 0 RasGAP C-terminus APG6_N PF17675.1 OAP64091.1 - 1.4 9.4 29.1 9 6.8 15.7 3.4 1 1 2 3 3 3 0 Apg6 coiled-coil region Golgin_A5 PF09787.9 OAP64091.1 - 2.6 7.5 17.3 0.03 13.8 8.2 2.0 2 0 0 2 2 2 0 Golgin subfamily A member 5 DUF1635 PF07795.11 OAP64091.1 - 8 6.3 11.3 0.037 13.9 1.2 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1635) AAA_13 PF13166.6 OAP64091.1 - 9.9 4.7 11.5 2.3 6.7 7.1 2.0 1 1 0 1 1 1 0 AAA domain ADH_N PF08240.12 OAP64092.1 - 1.5e-21 76.3 2.6 2.8e-21 75.5 2.6 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAP64092.1 - 4.5e-20 72.0 0.0 7.5e-20 71.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAP64092.1 - 3e-09 38.0 0.0 4.5e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 OAP64092.1 - 0.12 11.7 0.3 0.21 10.9 0.3 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF983 PF06170.12 OAP64092.1 - 1.1 9.7 0.0 1.1 9.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF983) Nucleopor_Nup85 PF07575.13 OAP64093.1 - 6.5e-25 87.7 0.1 2.8e-17 62.5 0.0 2.4 2 0 0 2 2 2 2 Nup85 Nucleoporin ORC6 PF05460.13 OAP64093.1 - 0.78 8.9 7.4 1.3 8.2 7.4 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Zn_clus PF00172.18 OAP64094.1 - 0.00014 21.9 12.6 0.00023 21.2 12.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAP64094.1 - 0.0053 15.8 1.0 0.0066 15.5 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain PCNA_C PF02747.15 OAP64094.1 - 0.097 12.8 0.0 0.25 11.5 0.0 1.6 1 0 0 1 1 1 0 Proliferating cell nuclear antigen, C-terminal domain TRP PF06011.12 OAP64095.1 - 2.5e-38 131.9 20.2 5.1e-37 127.6 20.2 2.1 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 OAP64095.1 - 5.9e-23 81.8 0.0 9.7e-23 81.1 0.0 1.4 1 0 0 1 1 1 1 ML-like domain DUF1772 PF08592.11 OAP64095.1 - 4.4 7.6 8.6 8.4 6.7 0.4 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) Zn_clus PF00172.18 OAP64096.1 - 0.00016 21.8 10.7 0.00028 21.0 10.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amidase PF01425.21 OAP64097.1 - 3.9e-86 289.8 0.0 6.3e-86 289.1 0.0 1.3 1 1 0 1 1 1 1 Amidase RNB PF00773.19 OAP64098.1 - 1.1e-23 84.1 0.1 2.9e-17 63.0 0.0 2.2 2 0 0 2 2 2 2 RNB domain SBDS_C PF09377.10 OAP64099.1 - 5.1e-41 139.3 0.1 1.1e-40 138.3 0.0 1.5 2 0 0 2 2 2 1 SBDS protein C-terminal domain SBDS PF01172.18 OAP64099.1 - 9.8e-35 118.5 0.3 1.8e-34 117.6 0.3 1.5 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein FliL PF03748.14 OAP64099.1 - 0.072 13.7 1.0 6.5 7.4 0.3 2.4 2 0 0 2 2 2 0 Flagellar basal body-associated protein FliL Apt1 PF10351.9 OAP64100.1 - 2.2 7.0 7.9 2.6 6.8 7.9 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain RNA_pol_Rpb2_6 PF00562.28 OAP64102.1 - 1.2e-122 409.8 0.4 1.8e-122 409.2 0.4 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 OAP64102.1 - 5.2e-50 169.8 0.0 1.1e-49 168.7 0.0 1.6 1 1 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 OAP64102.1 - 2.2e-35 122.0 0.0 4.3e-35 121.1 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 OAP64102.1 - 1.4e-33 115.1 0.3 4.6e-33 113.5 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 OAP64102.1 - 1.1e-24 86.4 0.1 2.4e-24 85.3 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 OAP64102.1 - 1.2e-19 70.6 0.4 3.7e-19 69.0 0.4 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RNA_pol_Rpb2_4 PF04566.13 OAP64102.1 - 1.3e-18 67.0 1.2 2.8e-18 66.0 0.2 2.2 3 0 0 3 3 3 1 RNA polymerase Rpb2, domain 4 MRNIP PF15749.5 OAP64102.1 - 0.00082 20.1 0.3 0.0017 19.0 0.3 1.5 1 0 0 1 1 1 1 MRN-interacting protein CTNNBL PF08216.11 OAP64103.1 - 4.4e-38 129.6 0.5 1.9e-37 127.6 0.0 2.4 2 0 0 2 2 2 1 Catenin-beta-like, Arm-motif containing nuclear Herpes_UL6 PF01763.16 OAP64103.1 - 0.043 12.3 0.2 0.081 11.4 0.2 1.4 1 0 0 1 1 1 0 Herpesvirus UL6 like Arm PF00514.23 OAP64103.1 - 0.043 13.9 0.1 1.5 9.0 0.1 2.6 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat Crl PF07417.12 OAP64103.1 - 0.066 13.3 0.1 22 5.1 0.0 2.8 2 0 0 2 2 2 0 Sigma factor-binding transcriptional regulator Crl Arrestin_N PF00339.29 OAP64104.1 - 0.068 13.2 0.1 0.48 10.5 0.0 2.4 2 1 0 2 2 2 0 Arrestin (or S-antigen), N-terminal domain WD40 PF00400.32 OAP64105.1 - 2.5e-13 50.3 7.1 6.8e-05 23.6 0.2 5.4 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAP64105.1 - 5.2e-12 45.9 0.2 0.02 15.2 0.0 4.6 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 OAP64105.1 - 0.00035 19.2 0.0 0.00073 18.2 0.0 1.6 1 0 0 1 1 1 1 Cytochrome D1 heme domain RNA_pol_Rpb1_5 PF04998.17 OAP64106.1 - 2.6e-101 338.5 0.1 3.8e-101 338.0 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.12 OAP64106.1 - 7.2e-96 321.2 0.0 1.1e-95 320.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 OAP64106.1 - 8.6e-77 257.0 0.0 1.5e-76 256.3 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 OAP64106.1 - 1.8e-57 194.2 0.4 3.1e-57 193.5 0.4 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.18 OAP64106.1 - 1.3e-44 151.9 0.0 2.6e-44 150.9 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.12 OAP64106.1 - 6.6e-41 139.5 2.0 1.5e-40 138.3 2.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.17 OAP64106.1 - 1.6e-34 118.1 0.2 4.1e-34 116.8 0.2 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.13 OAP64106.1 - 2.3e-14 52.9 228.4 0.0092 16.3 10.4 16.8 7 5 10 19 19 19 16 RNA polymerase Rpb1 C-terminal repeat CGI-121 PF08617.10 OAP64107.1 - 4.7e-41 140.6 0.1 1e-40 139.5 0.1 1.5 1 1 0 1 1 1 1 Kinase binding protein CGI-121 DUF3405 PF11885.8 OAP64108.1 - 2.2e-161 538.0 1.6 8.3e-148 493.2 0.5 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3405) adh_short PF00106.25 OAP64109.1 - 3.3e-34 118.1 0.1 4.2e-34 117.7 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP64109.1 - 3.2e-28 98.9 0.0 3.9e-28 98.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 OAP64109.1 - 2.2e-05 24.0 0.1 3.4e-05 23.4 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 OAP64109.1 - 0.00095 19.1 0.2 0.0016 18.4 0.2 1.5 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 OAP64109.1 - 0.0078 16.1 0.1 0.0098 15.8 0.1 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Viral_protease PF08715.10 OAP64109.1 - 0.028 13.8 0.0 0.037 13.4 0.0 1.2 1 0 0 1 1 1 0 Papain like viral protease FtsJ PF01728.19 OAP64109.1 - 0.056 13.5 0.0 0.082 13.0 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase THF_DHG_CYH_C PF02882.19 OAP64109.1 - 0.11 11.8 0.1 13 5.1 0.0 2.2 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Oxidored_FMN PF00724.20 OAP64110.1 - 2e-60 204.9 0.0 4.4e-58 197.2 0.0 2.5 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Cu-oxidase_3 PF07732.15 OAP64111.1 - 5.4e-26 90.9 0.2 1.7e-25 89.3 0.0 2.0 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.22 OAP64111.1 - 1.2e-25 90.5 0.0 2e-25 89.7 0.0 1.4 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 OAP64111.1 - 1.1e-18 67.4 0.9 1.7e-14 53.7 0.8 3.7 3 1 0 3 3 3 2 Multicopper oxidase Ceramidse_alk_C PF17048.5 OAP64111.1 - 0.016 15.1 0.0 0.034 14.0 0.0 1.5 1 0 0 1 1 1 0 Neutral/alkaline non-lysosomal ceramidase, C-terminal MFS_1 PF07690.16 OAP64112.1 - 6.3e-33 114.2 26.9 7.8e-33 113.9 26.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Bax1-I PF01027.20 OAP64113.1 - 6.4e-33 114.3 8.9 9.2e-33 113.8 8.9 1.2 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Hist_deacetyl PF00850.19 OAP64114.1 - 7.3e-57 193.2 0.0 9.6e-57 192.8 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Clr5 PF14420.6 OAP64115.1 - 6.6e-15 55.1 3.4 1.6e-14 53.9 3.4 1.7 1 0 0 1 1 1 1 Clr5 domain HTH_33 PF13592.6 OAP64115.1 - 0.029 14.0 0.0 0.055 13.1 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn helix ABC_trans_N PF14510.6 OAP64115.1 - 0.69 10.6 4.7 1.2 9.8 4.0 1.8 1 1 0 1 1 1 0 ABC-transporter N-terminal Fungal_trans PF04082.18 OAP64116.1 - 2e-19 69.7 0.0 2.3e-18 66.2 0.0 2.3 2 0 0 2 2 2 1 Fungal specific transcription factor domain Slx4 PF09494.10 OAP64116.1 - 1.8e-13 50.2 0.0 3.9e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 Slx4 endonuclease Zn_clus PF00172.18 OAP64116.1 - 0.0017 18.4 6.0 0.0033 17.5 6.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain bZIP_1 PF00170.21 OAP64117.1 - 1.9e-08 34.3 10.5 6.4e-08 32.6 10.5 1.8 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 OAP64117.1 - 3.6e-05 23.8 10.2 7.3e-05 22.8 10.2 1.6 1 1 0 1 1 1 1 Basic region leucine zipper Herpes_UL6 PF01763.16 OAP64117.1 - 0.0047 15.5 1.0 0.0054 15.3 1.0 1.1 1 0 0 1 1 1 1 Herpesvirus UL6 like bZIP_Maf PF03131.17 OAP64117.1 - 0.0088 16.5 7.5 0.019 15.5 7.5 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor TSC22 PF01166.18 OAP64117.1 - 0.037 14.3 0.4 0.068 13.5 0.4 1.4 1 0 0 1 1 1 0 TSC-22/dip/bun family DUF5094 PF17015.5 OAP64117.1 - 0.047 13.8 3.4 0.064 13.4 3.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5094) Jnk-SapK_ap_N PF09744.9 OAP64117.1 - 0.6 10.3 7.9 0.91 9.7 7.9 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 AMP-binding PF00501.28 OAP64118.1 - 2.4e-70 237.3 0.0 3.8e-70 236.6 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAP64118.1 - 2e-10 41.5 0.0 4.2e-10 40.5 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Myb_DNA-binding PF00249.31 OAP64119.1 - 7e-14 51.7 3.1 1.4e-08 34.8 0.5 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OAP64119.1 - 1.4e-09 38.1 1.8 6.3e-06 26.4 0.2 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OAP64119.1 - 0.053 13.4 0.4 0.098 12.6 0.3 1.4 1 1 0 1 1 1 0 Myb DNA-binding like DUF3084 PF11283.8 OAP64121.1 - 0.11 12.5 0.6 0.21 11.6 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3084) p450 PF00067.22 OAP64122.1 - 4.2e-57 193.9 0.0 2.4e-56 191.4 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 PDR_assoc PF08370.11 OAP64122.1 - 0.14 11.9 1.7 0.29 10.9 1.7 1.5 1 0 0 1 1 1 0 Plant PDR ABC transporter associated adh_short_C2 PF13561.6 OAP64123.1 - 1.8e-47 161.9 1.9 2.2e-47 161.6 1.9 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP64123.1 - 2e-41 141.6 0.7 3.3e-41 140.9 0.7 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAP64123.1 - 2.3e-10 40.7 0.3 3.8e-10 40.0 0.3 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 OAP64123.1 - 0.22 10.9 0.0 0.31 10.4 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Abhydrolase_3 PF07859.13 OAP64124.1 - 4.9e-44 150.7 0.0 7.1e-44 150.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 OAP64124.1 - 2.5e-09 36.6 0.4 1.3e-08 34.2 0.4 1.8 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 OAP64124.1 - 0.13 11.7 0.1 0.83 9.1 0.2 2.0 2 0 0 2 2 2 0 Prolyl oligopeptidase family Stress-antifung PF01657.17 OAP64125.1 - 1.4 9.6 4.2 0.96 10.1 1.9 2.0 2 1 0 2 2 2 0 Salt stress response/antifungal DUF2205 PF10224.9 OAP64127.1 - 2.2e-31 107.7 1.0 2.6e-31 107.4 1.0 1.0 1 0 0 1 1 1 1 Short coiled-coil protein YabA PF06156.13 OAP64127.1 - 0.0019 18.8 0.5 0.002 18.7 0.5 1.1 1 0 0 1 1 1 1 Initiation control protein YabA HrpB7 PF09486.10 OAP64127.1 - 0.002 18.5 1.2 0.0024 18.3 1.2 1.1 1 0 0 1 1 1 1 Bacterial type III secretion protein (HrpB7) DUF4201 PF13870.6 OAP64127.1 - 0.0034 17.1 0.7 0.0041 16.9 0.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) CASP_C PF08172.12 OAP64127.1 - 0.01 15.2 1.0 0.012 15.0 1.0 1.1 1 0 0 1 1 1 0 CASP C terminal HALZ PF02183.18 OAP64127.1 - 0.011 15.9 3.1 0.54 10.5 0.0 2.2 1 1 1 2 2 2 0 Homeobox associated leucine zipper TSC22 PF01166.18 OAP64127.1 - 0.012 15.9 0.8 0.27 11.6 0.1 2.2 1 1 1 2 2 2 0 TSC-22/dip/bun family PI3K_P85_iSH2 PF16454.5 OAP64127.1 - 0.015 14.9 1.0 0.018 14.6 1.0 1.1 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Snapin_Pallidin PF14712.6 OAP64127.1 - 0.036 14.5 0.3 0.045 14.2 0.3 1.2 1 0 0 1 1 1 0 Snapin/Pallidin IFT20 PF14931.6 OAP64127.1 - 0.036 14.2 0.7 0.049 13.8 0.7 1.2 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 LCD1 PF09798.9 OAP64127.1 - 0.038 12.5 1.9 0.041 12.4 1.9 1.0 1 0 0 1 1 1 0 DNA damage checkpoint protein P4Ha_N PF08336.11 OAP64127.1 - 0.039 14.0 0.4 0.046 13.7 0.4 1.2 1 0 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Fmp27_WPPW PF10359.9 OAP64127.1 - 0.044 12.6 2.2 0.048 12.5 2.2 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Baculo_PEP_C PF04513.12 OAP64127.1 - 0.046 13.8 0.2 0.055 13.5 0.2 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus CCDC24 PF15669.5 OAP64127.1 - 0.053 13.4 1.5 0.18 11.7 1.6 1.7 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 24 family DUF3958 PF13125.6 OAP64127.1 - 0.053 13.7 3.0 0.18 12.1 1.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3958) Fib_alpha PF08702.10 OAP64127.1 - 0.053 13.7 0.4 0.057 13.6 0.4 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DivIC PF04977.15 OAP64127.1 - 0.28 11.0 2.3 0.54 10.1 2.3 1.6 1 1 0 1 1 1 0 Septum formation initiator Sugar_tr PF00083.24 OAP64129.1 - 1e-117 393.8 25.9 1.9e-117 392.9 25.9 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP64129.1 - 1.7e-22 79.9 71.8 1.4e-20 73.6 36.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Mersacidin PF16934.5 OAP64129.1 - 0.14 12.0 0.0 0.63 9.9 0.0 2.1 1 0 0 1 1 1 0 Two-component Enterococcus faecalis cytolysin (EFC) Glyco_hydro_3_C PF01915.22 OAP64130.1 - 2e-36 125.9 0.0 4.1e-36 124.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 OAP64130.1 - 1.4e-34 119.9 0.0 2.2e-34 119.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 OAP64130.1 - 6.9e-05 22.9 0.0 0.00015 21.8 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain SPRY PF00622.28 OAP64131.1 - 3.4e-06 27.2 0.0 1.2e-05 25.5 0.0 1.9 2 1 1 3 3 3 1 SPRY domain Glyco_tranf_2_3 PF13641.6 OAP64132.1 - 2.9e-33 115.7 0.0 4.4e-33 115.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 OAP64132.1 - 1.8e-11 44.1 0.0 3.3e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 OAP64132.1 - 1.8e-10 40.6 0.0 1e-09 38.1 0.0 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glyco_hydro_18 PF00704.28 OAP64134.1 - 2.4e-19 70.2 0.0 6.7e-19 68.7 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 HSP20 PF00011.21 OAP64135.1 - 1.6e-08 34.6 0.2 3.3e-08 33.6 0.2 1.5 1 0 0 1 1 1 1 Hsp20/alpha crystallin family DUF4407 PF14362.6 OAP64135.1 - 0.16 11.3 1.5 0.25 10.7 1.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) p450 PF00067.22 OAP64136.1 - 1.1e-42 146.4 0.0 1.4e-41 142.8 0.0 2.1 1 1 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.18 OAP64138.1 - 1.5e-09 37.3 0.0 2.4e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP64138.1 - 6.3e-05 23.0 10.2 0.00012 22.1 10.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NRDE-2 PF08424.10 OAP64139.1 - 6.4e-85 285.1 2.2 6.4e-85 285.1 2.2 3.1 3 0 0 3 3 3 1 NRDE-2, necessary for RNA interference BP28CT PF08146.12 OAP64139.1 - 7.3e-31 107.1 0.0 2.6e-30 105.4 0.0 2.1 1 0 0 1 1 1 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.8 OAP64139.1 - 2.4e-12 47.2 0.1 2.4e-12 47.2 0.1 4.4 3 0 0 3 3 3 1 U3 small nucleolar RNA-associated protein 10 HEAT PF02985.22 OAP64139.1 - 0.00016 21.7 6.4 0.035 14.4 0.1 5.8 5 0 0 5 5 5 1 HEAT repeat Adaptin_N PF01602.20 OAP64139.1 - 0.00036 19.2 4.2 0.14 10.7 0.2 3.2 3 0 0 3 3 3 2 Adaptin N terminal region HEAT_2 PF13646.6 OAP64139.1 - 0.11 12.9 9.6 2 8.9 0.0 5.4 6 1 0 6 6 6 0 HEAT repeats HEAT_EZ PF13513.6 OAP64139.1 - 0.11 13.0 8.7 0.96 10.0 0.0 6.0 6 0 0 6 6 6 0 HEAT-like repeat Cnd1 PF12717.7 OAP64139.1 - 0.12 12.5 0.0 0.54 10.3 0.0 2.2 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 Piwi PF02171.17 OAP64140.1 - 5.5e-49 167.0 0.0 1e-48 166.2 0.0 1.4 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 OAP64140.1 - 1e-10 42.4 0.0 2.1e-10 41.4 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoMid PF16487.5 OAP64140.1 - 0.0034 17.6 0.3 0.0076 16.5 0.3 1.6 1 0 0 1 1 1 1 Mid domain of argonaute RtcR PF06956.11 OAP64140.1 - 0.083 12.3 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 Regulator of RNA terminal phosphate cyclase Polyketide_cyc2 PF10604.9 OAP64141.1 - 6.9e-12 45.8 0.8 9.3e-12 45.4 0.8 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 OAP64141.1 - 2.9e-06 27.5 1.4 3.4e-06 27.3 1.4 1.3 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport HEAT PF02985.22 OAP64142.1 - 5.6e-09 35.5 1.1 0.1 12.9 0.0 5.6 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.6 OAP64142.1 - 2.5e-05 24.7 4.0 0.014 15.9 0.2 4.4 5 0 0 5 5 5 2 HEAT-like repeat HEAT_2 PF13646.6 OAP64142.1 - 0.0002 21.7 4.6 0.0015 18.9 0.9 4.2 4 1 0 4 4 4 1 HEAT repeats Cohesin_HEAT PF12765.7 OAP64142.1 - 0.022 15.1 0.1 0.13 12.6 0.0 2.5 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion Vac14_Fab1_bd PF12755.7 OAP64142.1 - 0.084 13.5 0.0 2.5 8.8 0.0 3.0 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region DUF1349 PF07081.11 OAP64143.1 - 5.4e-27 94.7 0.0 6.3e-27 94.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) Abhydrolase_1 PF00561.20 OAP64144.1 - 4.1e-13 49.6 0.1 2.2e-10 40.6 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAP64144.1 - 0.0011 18.3 0.0 0.022 14.0 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Muraidase PF11860.8 OAP64144.1 - 0.0099 16.1 0.0 0.05 13.8 0.0 2.0 1 1 0 1 1 1 1 N-acetylmuramidase Abhydrolase_6 PF12697.7 OAP64144.1 - 0.049 14.2 0.0 0.073 13.7 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family Flavin_Reduct PF01613.18 OAP64145.1 - 5.7e-15 55.7 0.0 9.3e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 Flavin reductase like domain SSF PF00474.17 OAP64146.1 - 1e-07 31.2 27.8 1.5e-06 27.4 27.8 2.4 1 1 0 1 1 1 1 Sodium:solute symporter family NOA36 PF06524.12 OAP64147.1 - 0.23 10.7 1.9 0.44 9.8 1.9 1.4 1 0 0 1 1 1 0 NOA36 protein CAP59_mtransfer PF11735.8 OAP64148.1 - 1.2e-72 244.5 0.0 1.6e-72 244.1 0.0 1.2 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 NmrA PF05368.13 OAP64149.1 - 3.1e-09 36.8 0.0 3.1e-09 36.8 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NmrA PF05368.13 OAP64150.1 - 8.4e-16 58.2 0.0 1e-15 57.9 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAP64150.1 - 5.2e-09 36.3 0.0 6.3e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 OAP64150.1 - 0.0028 17.9 0.0 0.0039 17.4 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 OAP64150.1 - 0.0045 16.5 0.0 0.0063 16.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sipho_Gp37 PF14594.6 OAP64151.1 - 0.053 12.5 0.0 0.086 11.8 0.0 1.2 1 0 0 1 1 1 0 Siphovirus ReqiPepy6 Gp37-like protein Pro_CA PF00484.19 OAP64152.1 - 1.9e-13 51.0 0.0 7e-13 49.2 0.0 1.9 1 1 0 1 1 1 1 Carbonic anhydrase AAA_17 PF13207.6 OAP64152.1 - 0.16 12.4 0.0 4.1 7.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain PAP_central PF04928.17 OAP64153.1 - 7.1e-101 336.4 0.0 9.6e-101 335.9 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 OAP64153.1 - 7e-48 162.5 0.1 1.1e-47 161.8 0.1 1.3 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 OAP64153.1 - 4.6e-09 36.5 0.2 1.8e-08 34.6 0.0 2.0 1 1 1 2 2 2 1 Nucleotidyltransferase domain HTH_IclR PF09339.10 OAP64153.1 - 0.062 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 IclR helix-turn-helix domain Aconitase_B_N PF11791.8 OAP64153.1 - 0.12 12.5 0.2 0.29 11.2 0.2 1.6 1 0 0 1 1 1 0 Aconitate B N-terminal domain Polbeta PF18765.1 OAP64153.1 - 0.15 12.1 0.2 4.4 7.5 0.0 2.5 2 0 0 2 2 2 0 Polymerase beta, Nucleotidyltransferase DUF2235 PF09994.9 OAP64154.1 - 8.8e-81 271.4 0.0 1.2e-80 270.9 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) FA_hydroxylase PF04116.13 OAP64154.1 - 3.3 8.1 8.8 3.5 8.0 2.7 2.9 3 0 0 3 3 3 0 Fatty acid hydroxylase superfamily Amidase PF01425.21 OAP64155.1 - 2.8e-87 293.5 0.0 4e-87 293.1 0.0 1.2 1 0 0 1 1 1 1 Amidase PAF-AH_p_II PF03403.13 OAP64156.1 - 6.5e-57 192.8 0.0 2.1e-52 177.9 0.0 2.9 2 1 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 OAP64156.1 - 4e-08 32.5 0.0 2e-06 26.9 0.0 2.6 3 0 0 3 3 3 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 OAP64156.1 - 0.00012 21.4 0.1 0.023 13.9 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Chlorophyllase PF07224.11 OAP64156.1 - 0.00081 18.5 0.0 0.0028 16.7 0.0 1.8 2 0 0 2 2 2 1 Chlorophyllase DLH PF01738.18 OAP64156.1 - 0.057 13.0 0.0 0.65 9.5 0.0 2.4 2 1 1 3 3 3 0 Dienelactone hydrolase family FAA_hydrolase PF01557.18 OAP64157.1 - 3.9e-49 167.3 0.0 6.2e-49 166.6 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 OAP64157.1 - 2.8e-23 82.2 0.0 2.1e-22 79.3 0.0 2.5 2 0 0 2 2 2 1 Fumarylacetoacetase N-terminal Glyco_hydro_76 PF03663.14 OAP64158.1 - 1.9e-20 73.7 1.3 3e-19 69.8 0.0 2.8 3 1 0 3 3 3 1 Glycosyl hydrolase family 76 Aldo_ket_red PF00248.21 OAP64159.1 - 9.9e-58 195.6 0.0 1.1e-57 195.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Myb_DNA-binding PF00249.31 OAP64160.1 - 0.003 17.7 1.1 0.0063 16.7 1.1 1.5 1 1 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OAP64160.1 - 0.031 14.5 0.2 0.053 13.8 0.2 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain ER_lumen_recept PF00810.18 OAP64161.1 - 2e-44 152.0 9.6 3.2e-44 151.3 9.6 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.14 OAP64161.1 - 0.0076 16.0 7.6 0.034 13.9 0.0 3.2 3 1 0 3 3 3 2 PQ loop repeat Aldo_ket_red PF00248.21 OAP64162.1 - 1.7e-38 132.5 0.0 4e-36 124.7 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family 7TM_GPCR_Sra PF02117.16 OAP64163.1 - 0.032 13.1 0.2 0.053 12.3 0.2 1.3 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Sra CcmF_C PF16327.5 OAP64163.1 - 0.064 12.5 1.0 0.1 11.8 1.0 1.2 1 0 0 1 1 1 0 Cytochrome c-type biogenesis protein CcmF C-terminal DUF2628 PF10947.8 OAP64163.1 - 0.11 12.9 0.4 0.21 11.9 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2628) COX5B PF01215.19 OAP64165.1 - 8.5e-51 171.0 0.0 1.2e-50 170.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb zf-CCCH PF00642.24 OAP64166.1 - 3.2e-08 33.3 20.0 3e-07 30.2 2.5 3.1 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.22 OAP64166.1 - 0.0015 18.3 0.0 0.0023 17.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Torus PF16131.5 OAP64166.1 - 0.0044 17.7 1.6 0.5 11.1 0.2 2.5 2 0 0 2 2 2 2 Torus domain zf_CCCH_4 PF18345.1 OAP64166.1 - 0.0058 16.7 3.3 0.0058 16.7 3.3 3.3 3 0 0 3 3 3 1 Zinc finger domain zf-CCCH_3 PF15663.5 OAP64166.1 - 3.1 8.1 8.4 0.46 10.7 1.3 2.4 2 2 0 2 2 2 0 Zinc-finger containing family DUF2721 PF11026.8 OAP64167.1 - 0.0018 18.1 0.1 0.002 18.0 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2721) Mid2 PF04478.12 OAP64167.1 - 0.0096 15.8 0.0 0.011 15.5 0.0 1.1 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor DUF2116 PF09889.9 OAP64167.1 - 0.022 14.7 0.4 0.033 14.1 0.4 1.3 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) MSP1a PF11670.8 OAP64167.1 - 0.024 13.9 0.1 0.027 13.8 0.1 1.1 1 0 0 1 1 1 0 Major surface protein 1a (MSP1a) DUF3040 PF11239.8 OAP64167.1 - 0.028 14.7 0.8 0.078 13.3 0.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3040) SNARE PF05739.19 OAP64167.1 - 0.031 14.3 0.1 0.05 13.6 0.1 1.4 1 0 0 1 1 1 0 SNARE domain CobD_Cbib PF03186.13 OAP64167.1 - 0.1 11.8 0.1 0.11 11.7 0.1 1.1 1 0 0 1 1 1 0 CobD/Cbib protein GRA6 PF05084.13 OAP64167.1 - 0.1 12.5 0.1 0.12 12.3 0.1 1.2 1 0 0 1 1 1 0 Granule antigen protein (GRA6) DUF3976 PF13121.6 OAP64167.1 - 0.11 12.6 2.9 0.16 12.1 2.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3976) DUF5305 PF17231.2 OAP64167.1 - 0.14 11.5 0.0 0.18 11.2 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5305) An_peroxidase PF03098.15 OAP64169.1 - 1.8e-117 393.1 0.0 2.3e-117 392.8 0.0 1.0 1 0 0 1 1 1 1 Animal haem peroxidase Peroxidase_2 PF01328.17 OAP64170.1 - 4.9e-44 151.1 0.0 6.5e-44 150.7 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 Ribonuclease_T2 PF00445.18 OAP64170.1 - 0.24 11.6 0.0 0.35 11.1 0.0 1.2 1 0 0 1 1 1 0 Ribonuclease T2 family Aminotran_3 PF00202.21 OAP64171.1 - 3.3e-117 391.6 0.0 4.1e-117 391.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 OAP64171.1 - 0.002 17.4 0.0 0.011 15.0 0.0 1.8 2 0 0 2 2 2 1 Aminotransferase class I and II DUF3301 PF11743.8 OAP64171.1 - 0.068 12.9 0.2 0.15 11.8 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3301) TRI12 PF06609.13 OAP64172.1 - 5.9e-18 64.6 21.9 8e-18 64.2 21.9 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAP64172.1 - 1.7e-17 63.4 49.4 1.7e-17 63.4 49.4 3.0 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF4017 PF13209.6 OAP64172.1 - 0.049 13.6 6.4 0.061 13.2 1.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4017) 4HBT PF03061.22 OAP64174.1 - 2.2e-10 40.7 0.1 3e-10 40.3 0.1 1.2 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 OAP64174.1 - 1.8e-05 25.1 0.0 2.3e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT_2 PF13279.6 OAP64174.1 - 0.037 14.5 0.0 0.047 14.2 0.0 1.2 1 0 0 1 1 1 0 Thioesterase-like superfamily Cys_Met_Meta_PP PF01053.20 OAP64176.1 - 1.1e-60 205.2 0.0 2.8e-60 203.9 0.0 1.7 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 OAP64176.1 - 0.013 14.4 0.0 0.024 13.6 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V Aminotran_1_2 PF00155.21 OAP64176.1 - 0.024 13.8 0.0 0.045 12.9 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class I and II SelA PF03841.13 OAP64176.1 - 0.093 11.7 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 L-seryl-tRNA selenium transferase RdRP PF05183.12 OAP64177.1 - 1.1e-174 582.3 0.0 1.4e-174 582.0 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase GMC_oxred_N PF00732.19 OAP64178.1 - 2.6e-55 187.9 0.0 3.4e-55 187.5 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAP64178.1 - 1.2e-31 110.2 0.2 2.4e-31 109.2 0.2 1.6 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 OAP64178.1 - 0.00011 21.5 2.2 0.00067 18.8 2.2 2.1 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 OAP64178.1 - 0.00045 20.4 0.7 0.0013 18.9 0.7 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 OAP64178.1 - 0.0012 18.0 1.4 0.0042 16.2 0.3 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.17 OAP64178.1 - 0.0017 17.6 0.8 0.1 11.8 0.0 2.5 3 0 0 3 3 3 1 Thi4 family Pyr_redox_2 PF07992.14 OAP64178.1 - 0.0065 15.7 0.0 0.015 14.6 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAP64178.1 - 0.085 12.4 5.7 0.36 10.4 5.7 2.1 1 1 0 1 1 1 0 FAD dependent oxidoreductase Lactamase_B PF00753.27 OAP64179.1 - 7.4e-10 39.2 0.2 1.3e-09 38.4 0.2 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OAP64179.1 - 0.00013 21.5 0.1 0.00029 20.4 0.1 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Fungal_trans PF04082.18 OAP64180.1 - 1.4e-05 24.2 0.1 2.8e-05 23.3 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 OAP64180.1 - 0.015 15.8 0.8 0.22 12.1 0.2 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAP64180.1 - 0.088 13.7 0.2 0.39 11.7 0.2 2.2 1 0 0 1 1 1 0 C2H2-type zinc finger adh_short_C2 PF13561.6 OAP64181.1 - 3.6e-58 196.9 0.0 4.4e-58 196.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP64181.1 - 5.2e-44 150.0 0.0 6.2e-44 149.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Sacchrp_dh_NADP PF03435.18 OAP64181.1 - 0.007 16.6 0.0 0.012 15.8 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 OAP64181.1 - 0.012 15.1 0.0 0.019 14.4 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family KR PF08659.10 OAP64181.1 - 0.029 14.3 0.0 0.052 13.5 0.0 1.4 1 0 0 1 1 1 0 KR domain Polysacc_synt_2 PF02719.15 OAP64181.1 - 0.098 11.8 0.1 0.14 11.2 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Sugar_tr PF00083.24 OAP64182.1 - 6.2e-81 272.5 23.4 7.2e-81 272.3 23.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP64182.1 - 1.9e-23 83.0 37.7 2e-18 66.5 25.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MerR-DNA-bind PF09278.11 OAP64182.1 - 0.2 12.2 0.1 0.35 11.4 0.1 1.3 1 0 0 1 1 1 0 MerR, DNA binding DUF4387 PF14330.6 OAP64183.1 - 1.9e-35 121.5 0.0 3.3e-35 120.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4387) AtuA PF07287.11 OAP64183.1 - 4.5e-21 75.0 0.0 1.2e-20 73.5 0.0 1.6 1 1 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA Aldedh PF00171.22 OAP64184.1 - 3.6e-153 510.4 0.4 4.1e-153 510.2 0.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family adh_short_C2 PF13561.6 OAP64185.1 - 1.9e-70 237.1 1.4 2.1e-70 236.9 1.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP64185.1 - 2.3e-44 151.2 0.2 2.8e-44 150.9 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAP64185.1 - 1.4e-12 47.9 0.3 1.7e-12 47.6 0.3 1.3 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 OAP64185.1 - 0.00016 20.8 0.0 0.013 14.5 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 OAP64185.1 - 0.0035 16.8 0.2 0.023 14.2 0.2 2.1 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family T4SS PF07996.11 OAP64185.1 - 0.18 12.2 0.0 0.26 11.7 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion system proteins Fungal_trans PF04082.18 OAP64186.1 - 5.1e-14 51.9 0.0 8.3e-14 51.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.18 OAP64187.1 - 4.3e-07 29.2 0.1 8e-07 28.4 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sugar_tr PF00083.24 OAP64188.1 - 3.4e-94 316.3 28.6 3.8e-94 316.1 28.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP64188.1 - 5.8e-23 81.4 60.9 5.8e-21 74.8 32.4 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3007 PF11460.8 OAP64188.1 - 9.7 6.5 10.6 4 7.7 0.9 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3007) FMO-like PF00743.19 OAP64189.1 - 1.1e-16 60.4 0.0 1.5e-14 53.3 0.0 3.4 3 1 0 3 3 3 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OAP64189.1 - 7.3e-12 45.4 0.0 3.6e-11 43.1 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAP64189.1 - 1.6e-10 40.8 0.0 1.3e-07 31.1 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAP64189.1 - 4.3e-08 32.7 0.0 5.9e-05 22.4 0.0 3.8 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 OAP64189.1 - 6.8e-06 25.6 0.0 0.00038 19.8 0.0 2.9 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAP64189.1 - 0.0002 21.4 0.0 0.01 15.9 0.0 2.9 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.24 OAP64189.1 - 0.0052 16.4 3.3 0.19 11.3 0.0 3.2 2 1 0 3 3 3 1 FAD dependent oxidoreductase HI0933_like PF03486.14 OAP64189.1 - 0.083 11.6 0.3 0.46 9.1 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein M60-like_N PF17291.2 OAP64189.1 - 0.089 12.7 0.0 0.3 11.0 0.0 1.8 2 0 0 2 2 2 0 N-terminal domain of M60-like peptidases PEP_mutase PF13714.6 OAP64190.1 - 2.1e-44 151.7 1.6 2.5e-44 151.5 1.6 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 OAP64190.1 - 7.5e-19 67.6 0.1 1.2e-18 66.9 0.1 1.2 1 0 0 1 1 1 1 Isocitrate lyase family MR_MLE_C PF13378.6 OAP64190.1 - 0.1 12.1 0.4 0.26 10.8 0.1 1.9 2 1 0 2 2 2 0 Enolase C-terminal domain-like PYST-C1 PF09690.10 OAP64191.1 - 0.049 13.4 5.0 0.086 12.6 5.0 1.5 1 0 0 1 1 1 0 Plasmodium yoelii subtelomeric region (PYST-C1) WSN PF02206.18 OAP64191.1 - 0.069 13.1 0.1 0.15 12.0 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function CobU PF02283.16 OAP64192.1 - 0.17 11.5 0.1 0.31 10.6 0.1 1.3 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase RTA1 PF04479.13 OAP64193.1 - 1.5e-11 44.3 5.0 1.8e-11 44.1 5.0 1.0 1 0 0 1 1 1 1 RTA1 like protein PspB PF06667.12 OAP64193.1 - 0.24 11.5 2.0 0.32 11.1 1.2 1.7 1 1 0 1 1 1 0 Phage shock protein B ADH_zinc_N PF00107.26 OAP64196.1 - 2.1e-06 27.8 0.1 3.3e-06 27.1 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAP64196.1 - 0.0001 22.2 0.1 0.00025 20.9 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Pectate_lyase_3 PF12708.7 OAP64197.1 - 5.9e-97 323.7 21.0 4.9e-84 281.5 8.1 2.9 3 1 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 OAP64197.1 - 2.1e-09 37.0 1.7 0.00049 19.7 0.1 2.7 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Aminotran_1_2 PF00155.21 OAP64198.1 - 2.9e-21 76.1 0.0 3.7e-21 75.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 OAP64198.1 - 0.047 12.5 0.0 0.13 11.1 0.0 1.6 2 0 0 2 2 2 0 Alanine-glyoxylate amino-transferase RSRP PF17069.5 OAP64199.1 - 3.5 7.1 10.4 6.3 6.3 10.4 1.4 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 AMP-binding PF00501.28 OAP64200.1 - 2e-56 191.4 0.0 2.5e-56 191.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAP64200.1 - 1.1e-13 51.9 0.1 2.5e-13 50.8 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain NMO PF03060.15 OAP64200.1 - 0.073 12.4 0.1 0.11 11.9 0.1 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase CDC24 PF06395.11 OAP64200.1 - 0.16 12.3 0.0 0.34 11.2 0.0 1.5 1 0 0 1 1 1 0 CDC24 Calponin Zn_clus PF00172.18 OAP64202.1 - 1.2e-07 31.7 10.4 2.5e-07 30.7 10.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PARP PF00644.20 OAP64203.1 - 1.1e-29 103.4 0.0 2.6e-29 102.2 0.0 1.6 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain ADH_zinc_N PF00107.26 OAP64203.1 - 1.3e-08 34.8 0.2 2.9e-08 33.8 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase WGR PF05406.15 OAP64203.1 - 1.7e-08 34.4 0.1 3e-08 33.6 0.1 1.4 1 0 0 1 1 1 1 WGR domain ADH_N PF08240.12 OAP64203.1 - 0.13 12.1 0.0 0.32 10.9 0.0 1.6 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain PARP_reg PF02877.14 OAP64203.1 - 0.18 11.9 0.0 0.35 11.0 0.0 1.4 1 0 0 1 1 1 0 Poly(ADP-ribose) polymerase, regulatory domain p450 PF00067.22 OAP64204.1 - 7.3e-77 259.1 0.0 9e-77 258.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 TrkA_N PF02254.18 OAP64204.1 - 0.051 13.8 0.2 0.09 13.0 0.2 1.3 1 0 0 1 1 1 0 TrkA-N domain Sugar_tr PF00083.24 OAP64205.1 - 2.4e-62 211.3 23.6 6.5e-61 206.6 20.0 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 OAP64205.1 - 3.7e-22 78.7 41.9 4.6e-22 78.4 39.5 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily FMO-like PF00743.19 OAP64206.1 - 3.7e-18 65.3 0.0 1.5e-15 56.7 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OAP64206.1 - 2.6e-15 56.5 0.0 6.6e-15 55.1 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAP64206.1 - 2.3e-10 40.2 0.0 1.3e-07 31.2 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAP64206.1 - 4.8e-08 32.5 0.1 4.7e-07 29.3 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 OAP64206.1 - 3.6e-05 23.9 0.0 0.00012 22.3 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 OAP64206.1 - 0.00021 21.3 1.8 0.073 13.1 0.2 4.0 3 1 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.24 OAP64206.1 - 0.02 14.5 0.2 6.1 6.3 0.0 2.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 OAP64206.1 - 0.083 11.9 0.0 0.23 10.5 0.0 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein Thi4 PF01946.17 OAP64206.1 - 0.094 11.9 0.2 0.44 9.7 0.0 2.1 2 0 0 2 2 2 0 Thi4 family Fungal_trans PF04082.18 OAP64208.1 - 7.7e-19 67.8 2.6 7.7e-19 67.8 2.6 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain FMO-like PF00743.19 OAP64209.1 - 6e-11 41.5 0.5 7.9e-10 37.8 0.1 2.8 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OAP64209.1 - 2.7e-10 40.3 0.0 6.1e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAP64209.1 - 0.00019 21.1 0.1 0.077 12.6 0.1 3.0 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 OAP64209.1 - 0.00019 21.5 0.0 0.017 15.1 0.0 2.8 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 OAP64209.1 - 0.00026 20.3 0.1 0.13 11.5 0.0 3.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAP64209.1 - 0.00063 19.0 0.2 0.23 10.5 0.1 3.9 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 OAP64209.1 - 0.009 15.3 0.0 0.65 9.2 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAP64209.1 - 0.19 10.9 0.5 0.42 9.8 0.1 1.6 2 0 0 2 2 2 0 Thi4 family AMP-binding PF00501.28 OAP64210.1 - 1.3e-76 257.9 0.0 1.6e-76 257.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAP64210.1 - 2e-12 47.9 0.1 4.9e-12 46.7 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Beta-lactamase PF00144.24 OAP64211.1 - 1.8e-39 135.9 0.3 3e-39 135.2 0.3 1.3 1 1 0 1 1 1 1 Beta-lactamase Cyclase PF04199.13 OAP64212.1 - 1.5e-12 47.9 0.1 2.4e-12 47.3 0.1 1.4 1 1 0 1 1 1 1 Putative cyclase LPD22 PF18834.1 OAP64212.1 - 0.045 14.0 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 Large polyvalent protein associated domain 22 DUF2716 PF10898.8 OAP64212.1 - 0.13 12.6 0.3 0.39 11.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2716) Acyl-CoA_dh_1 PF00441.24 OAP64213.1 - 2.5e-25 89.5 0.2 3.5e-25 88.9 0.2 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 OAP64213.1 - 2.6e-24 85.2 0.0 4.3e-24 84.5 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 OAP64213.1 - 2e-20 73.5 0.0 6.3e-20 71.9 0.0 1.9 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 OAP64213.1 - 0.00061 20.1 0.0 0.0009 19.5 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain adh_short PF00106.25 OAP64214.1 - 8.2e-37 126.6 0.3 9.4e-37 126.4 0.3 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP64214.1 - 2.1e-31 109.3 0.1 2.4e-31 109.1 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP64214.1 - 6.7e-14 52.2 0.3 1e-13 51.6 0.3 1.3 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 OAP64214.1 - 0.05 13.5 1.4 0.24 11.2 0.5 2.2 2 1 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 OAP64214.1 - 0.11 12.5 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Fungal_trans PF04082.18 OAP64215.1 - 3.7e-17 62.2 0.5 5.6e-17 61.6 0.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Mito_fiss_reg PF05308.11 OAP64215.1 - 0.1 12.6 0.8 0.17 12.0 0.8 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator adh_short_C2 PF13561.6 OAP64216.1 - 1.1e-63 215.0 0.8 1.2e-63 214.8 0.8 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP64216.1 - 9e-50 168.9 0.9 1.1e-49 168.6 0.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAP64216.1 - 4.1e-11 43.1 0.6 7e-11 42.4 0.6 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAP64216.1 - 0.0017 17.9 0.2 0.01 15.3 0.2 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1533 PF07550.11 OAP64216.1 - 0.031 14.2 0.1 0.057 13.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1533) 3Beta_HSD PF01073.19 OAP64216.1 - 0.056 12.4 0.1 0.17 10.8 0.0 1.7 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family 3HCDH_N PF02737.18 OAP64216.1 - 0.35 10.7 1.1 0.51 10.2 0.2 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain adh_short_C2 PF13561.6 OAP64217.1 - 2.8e-43 148.2 3.8 1.9e-40 138.9 3.8 2.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP64217.1 - 9.6e-33 113.3 2.0 4.6e-31 107.8 2.0 2.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAP64217.1 - 2.3e-05 24.4 0.5 7.1e-05 22.8 0.3 1.8 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 OAP64217.1 - 0.036 13.2 0.0 0.048 12.8 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein FAD_binding_3 PF01494.19 OAP64218.1 - 9.5e-62 209.3 0.0 1.2e-61 208.9 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain RVT_3 PF13456.6 OAP64218.1 - 0.021 14.6 0.0 0.042 13.7 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase-like Pyr_redox_2 PF07992.14 OAP64218.1 - 0.064 12.5 0.0 0.12 11.5 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAP64218.1 - 0.12 12.6 0.0 0.34 11.2 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 OAP64218.1 - 0.2 10.8 0.0 0.72 9.0 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Cupin_8 PF13621.6 OAP64219.1 - 6.1e-49 167.0 0.0 9.6e-49 166.4 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 OAP64219.1 - 0.097 12.1 0.1 5 6.5 0.0 2.2 2 0 0 2 2 2 0 Cupin superfamily protein DUF4636 PF15468.6 OAP64219.1 - 0.099 12.3 0.1 2 8.0 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4636) HAD_2 PF13419.6 OAP64220.1 - 5.4e-25 88.5 0.0 8e-25 87.9 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OAP64220.1 - 5.4e-14 53.0 0.0 6.3e-13 49.5 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OAP64220.1 - 7.7e-07 29.1 0.0 1.5e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 OAP64220.1 - 9.1e-05 22.9 0.0 0.00012 22.5 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 OAP64220.1 - 0.0064 16.6 0.0 0.02 15.0 0.0 1.8 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase SAP18 PF06487.12 OAP64221.1 - 7e-44 149.4 0.0 8.9e-44 149.1 0.0 1.1 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) HTH_20 PF12840.7 OAP64222.1 - 0.06 13.4 0.1 0.8 9.8 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain Lactonase PF10282.9 OAP64223.1 - 1.2e-26 93.8 0.1 2e-25 89.8 0.1 2.3 2 1 0 2 2 2 1 Lactonase, 7-bladed beta-propeller SGL PF08450.12 OAP64223.1 - 0.00078 19.1 0.0 0.014 15.0 0.0 2.5 2 1 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region Nitroreductase PF00881.24 OAP64224.1 - 1.4e-15 57.8 0.0 1.6e-15 57.6 0.0 1.0 1 0 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 OAP64224.1 - 0.13 11.8 0.0 1.2 8.7 0.0 2.1 2 0 0 2 2 2 0 Putative TM nitroreductase MFS_1 PF07690.16 OAP64225.1 - 1.7e-45 155.5 45.1 1.1e-44 152.9 42.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAP64225.1 - 6.1e-11 41.8 22.8 3.7e-10 39.2 22.9 2.3 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 OAP64225.1 - 9.8e-05 21.0 4.8 0.00018 20.1 4.8 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAP64226.1 - 2.1e-06 26.9 29.0 0.00028 19.9 26.1 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily DUF4231 PF14015.6 OAP64226.1 - 4.2 7.9 6.8 4.9 7.7 2.9 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) WW PF00397.26 OAP64227.1 - 1.9e-05 24.6 1.7 5.1e-05 23.3 1.7 1.8 1 0 0 1 1 1 1 WW domain Eapp_C PF10238.9 OAP64228.1 - 0.019 15.1 3.5 0.037 14.1 3.5 1.6 1 0 0 1 1 1 0 E2F-associated phosphoprotein Presenilin PF01080.17 OAP64228.1 - 0.32 9.7 4.6 0.43 9.3 4.6 1.3 1 0 0 1 1 1 0 Presenilin DUF913 PF06025.12 OAP64228.1 - 1.1 8.2 4.1 1.7 7.6 4.1 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) RR_TM4-6 PF06459.12 OAP64228.1 - 1.3 8.8 17.4 2.2 8.0 17.4 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 EIIBC-GUT_N PF03612.14 OAP64228.1 - 2.7 7.7 9.2 4.8 6.9 9.2 1.4 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus CPSF100_C PF13299.6 OAP64228.1 - 2.9 8.0 12.6 3.9 7.6 11.3 1.9 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal NPR3 PF03666.13 OAP64228.1 - 3.4 6.3 10.3 4.6 5.9 10.3 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Coilin_N PF15862.5 OAP64228.1 - 5.7 6.8 21.1 12 5.7 21.1 1.5 1 0 0 1 1 1 0 Coilin N-terminus SpoIIP PF07454.11 OAP64228.1 - 8.6 5.7 15.0 13 5.1 15.0 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Sugar_tr PF00083.24 OAP64229.1 - 1.9e-73 247.9 31.6 2.3e-73 247.6 31.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP64229.1 - 6.8e-28 97.6 52.7 6.1e-25 87.9 30.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily SLC3A2_N PF16028.5 OAP64229.1 - 0.49 10.0 2.8 1.9 8.1 0.0 2.9 3 0 0 3 3 3 0 Solute carrier family 3 member 2 N-terminus DUF2070 PF09843.9 OAP64229.1 - 0.79 7.9 17.4 1.4 7.1 17.4 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) GST_N_3 PF13417.6 OAP64230.1 - 9.4e-13 48.4 0.1 2.8e-12 46.9 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OAP64230.1 - 1.2e-06 28.7 0.1 2.3e-06 27.8 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAP64230.1 - 0.00048 20.1 0.0 0.00098 19.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 OAP64230.1 - 0.059 14.1 0.0 0.48 11.2 0.0 2.2 1 1 0 1 1 1 0 Glutathione S-transferase N-terminal domain DUF2347 PF09804.9 OAP64231.1 - 5.3e-94 315.0 0.0 8.5e-94 314.3 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.6 OAP64231.1 - 2.4e-47 161.7 5.8 1.1e-33 117.0 0.4 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF4484) Avl9 PF09794.9 OAP64231.1 - 5e-06 25.5 0.5 0.046 12.4 0.1 2.7 3 0 0 3 3 3 2 Transport protein Avl9 SPA PF08616.10 OAP64231.1 - 0.0036 17.3 0.0 0.0073 16.3 0.0 1.5 1 0 0 1 1 1 1 Stabilization of polarity axis Abhydrolase_6 PF12697.7 OAP64233.1 - 3.3e-12 47.5 6.5 3.3e-12 47.5 6.5 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAP64233.1 - 3.3e-11 42.9 0.0 6e-11 42.1 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 OAP64233.1 - 2.6e-07 30.7 0.0 4e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 OAP64233.1 - 1.7e-06 27.9 0.1 2.9e-06 27.1 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OAP64233.1 - 0.033 13.6 0.0 0.16 11.5 0.0 2.1 1 1 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 OAP64233.1 - 0.035 13.9 0.0 0.63 9.8 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase ADH_N PF08240.12 OAP64234.1 - 1.5e-23 82.8 3.1 2.6e-23 82.0 3.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAP64234.1 - 7.7e-08 32.4 0.0 5.7e-07 29.6 0.0 2.3 1 1 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 OAP64234.1 - 0.00025 20.4 0.0 0.00045 19.6 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 OAP64234.1 - 0.00027 20.4 0.0 0.00088 18.7 0.0 1.8 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain XdhC_C PF13478.6 OAP64234.1 - 0.085 13.4 0.0 0.28 11.7 0.0 1.9 1 1 0 1 1 1 0 XdhC Rossmann domain PAN_1 PF00024.26 OAP64235.1 - 0.0016 18.4 0.7 0.0016 18.4 0.7 3.2 3 1 0 3 3 3 1 PAN domain DUF5349 PF17298.2 OAP64235.1 - 1.5 8.5 15.7 1.9 8.2 15.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5349) SNF2_N PF00176.23 OAP64236.1 - 1.4e-59 201.6 0.0 2.6e-59 200.7 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OAP64236.1 - 3.7e-14 53.0 0.0 8.3e-14 51.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAP64236.1 - 3.8e-12 46.5 0.0 1.1e-11 45.0 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 OAP64236.1 - 0.0032 17.2 0.1 0.011 15.4 0.0 1.9 2 0 0 2 2 2 1 SWI2/SNF2 ATPase DUF2075 PF09848.9 OAP64236.1 - 0.065 12.5 0.0 0.13 11.5 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) SSURE PF11966.8 OAP64236.1 - 0.091 12.5 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 Fibronectin-binding repeat TolA_bind_tri PF16331.5 OAP64238.1 - 0.85 9.7 3.4 0.83 9.8 1.8 1.8 2 0 0 2 2 2 0 TolA binding protein trimerisation FAD_binding_3 PF01494.19 OAP64239.1 - 5.7e-12 45.5 0.5 5.7e-12 45.5 0.5 2.3 2 1 0 2 2 2 1 FAD binding domain SE PF08491.10 OAP64239.1 - 2.9e-05 23.3 0.0 0.00061 18.9 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase NAD_binding_9 PF13454.6 OAP64239.1 - 3e-05 24.1 0.5 0.26 11.3 0.2 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Amino_oxidase PF01593.24 OAP64239.1 - 0.00051 19.5 0.0 0.00081 18.8 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 OAP64239.1 - 0.007 15.6 0.4 0.85 8.8 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAP64239.1 - 0.023 14.3 0.1 1.3 8.5 0.1 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase Macro PF01661.21 OAP64241.1 - 5.4e-12 45.8 0.0 3.2e-08 33.6 0.0 2.6 1 1 1 2 2 2 2 Macro domain MIF PF01187.18 OAP64241.1 - 5.7e-11 42.7 0.0 1e-10 41.9 0.0 1.4 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) DnaJ PF00226.31 OAP64241.1 - 0.11 12.6 1.2 0.17 12.0 0.2 1.9 2 0 0 2 2 2 0 DnaJ domain TruD PF01142.18 OAP64242.1 - 5.8e-61 206.6 0.0 1.3e-56 192.2 0.0 3.9 3 1 0 3 3 3 3 tRNA pseudouridine synthase D (TruD) CHASE PF03924.13 OAP64245.1 - 0.0099 15.8 0.0 0.083 12.8 0.0 2.3 2 0 0 2 2 2 1 CHASE domain Erf4 PF10256.9 OAP64245.1 - 0.032 14.4 0.0 0.069 13.3 0.0 1.6 1 0 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family MRNIP PF15749.5 OAP64246.1 - 0.13 13.0 0.4 0.33 11.7 0.4 1.6 1 0 0 1 1 1 0 MRN-interacting protein Phage_Mu_Gam PF07352.12 OAP64246.1 - 7.6 6.4 6.8 27 4.6 3.4 2.3 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein Bac_luciferase PF00296.20 OAP64248.1 - 0.011 15.2 0.0 0.011 15.2 0.0 1.1 1 0 0 1 1 1 0 Luciferase-like monooxygenase AIM3 PF17096.5 OAP64249.1 - 0.014 16.3 0.1 0.014 16.3 0.1 5.4 4 1 0 4 4 4 0 Altered inheritance of mitochondria protein 3 Lectin_like PF18560.1 OAP64249.1 - 0.063 13.4 0.1 0.1 12.7 0.1 1.3 1 0 0 1 1 1 0 Lectin like domain DUF4448 PF14610.6 OAP64250.1 - 0.00065 19.5 0.0 0.001 18.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) SKG6 PF08693.10 OAP64250.1 - 0.0021 17.4 3.0 0.0054 16.1 3.0 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain TMEM154 PF15102.6 OAP64250.1 - 0.88 9.5 4.8 3.5 7.5 4.2 2.2 1 1 0 1 1 1 0 TMEM154 protein family Apt1 PF10351.9 OAP64250.1 - 2 7.2 3.2 2.5 6.8 3.2 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain MFS_1 PF07690.16 OAP64251.1 - 3.3e-39 134.8 29.4 3.3e-39 134.8 29.4 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAP64251.1 - 1.5e-05 24.1 26.1 3.1e-05 23.0 26.1 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter VPS28 PF03997.12 OAP64252.1 - 7.8e-68 227.9 0.1 9.1e-68 227.7 0.1 1.1 1 0 0 1 1 1 1 VPS28 protein Noc2 PF03715.13 OAP64253.1 - 1.3e-125 418.6 0.3 2.5e-125 417.7 0.3 1.5 1 0 0 1 1 1 1 Noc2p family Nop14 PF04147.12 OAP64253.1 - 0.0013 17.0 0.3 0.0013 17.0 0.3 2.4 2 0 0 2 2 2 2 Nop14-like family XPC-binding PF09280.11 OAP64253.1 - 0.024 14.4 0.0 5.5 6.8 0.1 3.0 2 0 0 2 2 2 0 XPC-binding domain Glycos_transf_1 PF00534.20 OAP64254.1 - 1.5e-18 66.9 0.0 3.9e-18 65.6 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 OAP64254.1 - 9.8e-11 42.2 0.0 1.9e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 OAP64254.1 - 2.9e-05 24.4 0.1 9.3e-05 22.8 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 DUF2520 PF10728.9 OAP64254.1 - 0.12 12.2 0.0 0.29 10.9 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF2520) Pex19 PF04614.12 OAP64255.1 - 0.023 14.5 0.5 0.032 14.0 0.5 1.2 1 0 0 1 1 1 0 Pex19 protein family DUF2570 PF10828.8 OAP64255.1 - 0.93 9.3 4.2 4.1 7.3 4.4 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2570) DUF3328 PF11807.8 OAP64256.1 - 7.6e-20 71.6 1.4 7.6e-20 71.6 1.4 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3328) DUF3848 PF12959.7 OAP64257.1 - 0.0083 16.2 1.8 1 9.5 0.2 3.2 1 1 2 3 3 3 1 Protein of unknown function (DUF3848) WW_FCH_linker PF16623.5 OAP64257.1 - 0.048 14.4 7.9 14 6.5 0.3 3.6 1 1 3 4 4 4 0 Unstructured linker region between on GAS7 protein Mif2_N PF15624.6 OAP64257.1 - 0.064 14.0 17.5 1 10.0 1.8 3.2 1 1 2 3 3 3 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal DIM PF08194.12 OAP64257.1 - 0.29 11.4 1.3 0.44 10.8 1.3 1.2 1 0 0 1 1 1 0 DIM protein DUF3446 PF11928.8 OAP64257.1 - 2.2 8.6 11.9 1e+02 3.3 0.2 4.6 1 1 3 4 4 4 0 Early growth response N-terminal domain Pkinase PF00069.25 OAP64258.1 - 3.8e-40 137.9 0.0 4.9e-40 137.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP64258.1 - 1.8e-16 60.2 0.0 3.1e-16 59.4 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OAP64258.1 - 4.4e-05 22.9 0.0 0.00012 21.5 0.0 1.7 1 1 1 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OAP64258.1 - 0.00022 20.7 0.0 0.00032 20.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 OAP64258.1 - 0.00028 20.9 0.0 0.00086 19.3 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OAP64258.1 - 0.0017 17.2 0.0 0.0021 16.9 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 OAP64258.1 - 0.012 15.2 0.0 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 RIO1 family DUF4357 PF14267.6 OAP64260.1 - 0.11 12.5 0.9 7.7 6.5 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4357) adh_short PF00106.25 OAP64261.1 - 1.1e-39 136.0 0.1 2.1e-39 135.0 0.1 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP64261.1 - 1.9e-34 119.3 0.0 2.7e-34 118.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP64261.1 - 1.7e-08 34.6 0.0 2.4e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 KR domain Fungal_trans_2 PF11951.8 OAP64262.1 - 3.4e-09 36.0 1.1 7e-09 35.0 1.1 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain RTA1 PF04479.13 OAP64263.1 - 9.9e-65 218.0 14.4 1.3e-64 217.6 14.4 1.1 1 0 0 1 1 1 1 RTA1 like protein DUF423 PF04241.15 OAP64263.1 - 3.3 8.0 6.5 0.72 10.1 1.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF423) BaxI_1 PF12811.7 OAP64263.1 - 3.3 7.2 16.2 0.069 12.7 6.7 2.2 1 1 1 2 2 2 0 Bax inhibitor 1 like ADH_zinc_N_2 PF13602.6 OAP64264.1 - 1.7e-31 110.0 0.1 3.6e-31 109.0 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 OAP64264.1 - 1.5e-15 57.3 0.0 3e-15 56.4 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NTP_transf_6 PF06042.11 OAP64266.1 - 5.5e-54 182.3 0.0 6.4e-54 182.1 0.0 1.0 1 0 0 1 1 1 1 Nucleotidyltransferase Sugar_tr PF00083.24 OAP64267.1 - 3.2e-89 299.9 29.5 3.6e-89 299.7 29.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP64267.1 - 4.2e-27 95.0 62.8 3.2e-26 92.1 30.7 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_5 PF05631.14 OAP64267.1 - 5.2e-07 28.9 6.6 1.8e-05 23.8 0.3 2.4 2 0 0 2 2 2 2 Sugar-tranasporters, 12 TM TRI12 PF06609.13 OAP64267.1 - 5.3e-05 21.8 0.2 5.3e-05 21.8 0.2 2.2 3 0 0 3 3 3 1 Fungal trichothecene efflux pump (TRI12) Cu-oxidase_2 PF07731.14 OAP64268.1 - 4.9e-47 159.1 7.7 7e-42 142.4 0.7 3.1 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 OAP64268.1 - 2.3e-41 140.5 5.1 1.3e-39 134.9 0.9 3.2 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 OAP64268.1 - 7.2e-39 133.5 3.0 6e-32 111.0 0.2 3.2 3 0 0 3 3 3 3 Multicopper oxidase Self-incomp_S1 PF05938.11 OAP64268.1 - 0.15 12.6 0.5 33 5.1 0.4 2.4 2 0 0 2 2 2 0 Plant self-incompatibility protein S1 FTR1 PF03239.14 OAP64269.1 - 5.9e-88 295.0 8.4 7e-88 294.7 8.4 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family S_2TMBeta PF18153.1 OAP64269.1 - 4 7.2 6.2 0.38 10.5 0.7 2.1 2 1 1 3 3 3 0 SMODS-associating 2TM, beta-strand rich effector domain GPDPase_memb PF10110.9 OAP64269.1 - 8.6 5.0 11.4 0.31 9.8 0.2 2.8 3 0 0 3 3 3 0 Membrane domain of glycerophosphoryl diester phosphodiesterase 2OG-FeII_Oxy_3 PF13640.6 OAP64270.1 - 0.00078 20.3 0.0 0.0012 19.6 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-Fe_Oxy_2 PF10014.9 OAP64270.1 - 0.0091 15.8 0.0 0.025 14.4 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe dioxygenase Fungal_trans_2 PF11951.8 OAP64271.1 - 1e-09 37.7 0.1 6.4e-09 35.1 0.1 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain OTT_1508_deam PF14441.6 OAP64272.1 - 3.4e-19 68.6 0.0 6.5e-19 67.7 0.0 1.5 1 0 0 1 1 1 1 OTT_1508-like deaminase DUF2431 PF10354.9 OAP64272.1 - 0.18 12.1 0.0 0.33 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2431) MFS_1 PF07690.16 OAP64273.1 - 7.1e-44 150.2 40.9 2.5e-42 145.0 40.9 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 OAP64273.1 - 8.7e-14 50.9 15.5 1.1e-13 50.5 15.5 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 OAP64273.1 - 0.0012 17.2 13.2 0.0048 15.3 0.4 3.1 2 1 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family DUF2830 PF11125.8 OAP64273.1 - 0.32 11.0 1.0 7.9 6.6 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2830) Zn_clus PF00172.18 OAP64274.1 - 4.3 7.5 7.4 8.8 6.5 7.4 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Questin_oxidase PF14027.6 OAP64275.1 - 2.1e-78 264.3 0.0 2.5e-78 264.0 0.0 1.0 1 0 0 1 1 1 1 Questin oxidase-like Fungal_trans_2 PF11951.8 OAP64276.1 - 0.0017 17.2 0.0 0.03 13.2 0.0 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain DUF1772 PF08592.11 OAP64277.1 - 1.1e-31 110.0 1.9 1.4e-31 109.7 1.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) Fungal_trans PF04082.18 OAP64278.1 - 2.9e-30 105.2 0.0 4e-30 104.7 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP64278.1 - 5.1e-08 32.9 5.6 1e-07 31.9 5.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.25 OAP64279.1 - 2.5e-26 92.4 0.0 4.2e-26 91.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP64279.1 - 1.1e-18 67.7 0.0 1.9e-18 66.9 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 OAP64279.1 - 0.0033 16.9 0.0 0.087 12.3 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Fungal_trans PF04082.18 OAP64280.1 - 4.4e-17 62.0 0.8 9e-17 61.0 0.8 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain YdiH PF15930.5 OAP64280.1 - 0.011 15.9 0.0 0.025 14.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function Syntaxin-6_N PF09177.11 OAP64280.1 - 0.11 13.1 0.2 0.27 11.8 0.2 1.6 1 0 0 1 1 1 0 Syntaxin 6, N-terminal NMT1_3 PF16868.5 OAP64281.1 - 8.9e-10 38.4 0.0 1.3e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 NMT1-like family QslA_E PF18226.1 OAP64281.1 - 0.018 14.9 0.1 0.041 13.8 0.1 1.6 1 0 0 1 1 1 0 LasR-specific antiactivator QslA chain E rpo132 PF12415.8 OAP64281.1 - 0.064 12.5 0.0 0.18 11.1 0.0 1.7 1 0 0 1 1 1 0 Poxvirus DNA dependent RNA polymerase NAD_binding_10 PF13460.6 OAP64282.1 - 2.1e-14 53.8 0.0 3.5e-14 53.1 0.0 1.3 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 OAP64282.1 - 3.5e-06 26.7 0.0 5.3e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.24 OAP64282.1 - 0.0029 18.0 0.0 0.006 17.0 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 OAP64282.1 - 0.039 14.1 0.0 0.061 13.5 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Sacchrp_dh_NADP PF03435.18 OAP64282.1 - 0.065 13.5 0.0 0.1 12.8 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain MFS_1 PF07690.16 OAP64283.1 - 3.7e-19 68.9 38.8 3.7e-19 68.9 38.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_2_4 PF16082.5 OAP64283.1 - 7.5 6.4 8.1 2.3 8.0 0.4 3.1 3 0 0 3 3 3 0 Bacteriophage holin family, superfamily II-like Methyltransf_2 PF00891.18 OAP64284.1 - 7.8e-11 41.7 0.0 1.2e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_23 PF13489.6 OAP64284.1 - 0.0086 15.9 0.0 0.016 15.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Pkinase PF00069.25 OAP64285.1 - 0.0016 17.8 0.0 0.0018 17.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain AA_permease_2 PF13520.6 OAP64286.1 - 2.5e-63 214.4 47.8 3e-63 214.2 47.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAP64286.1 - 8.8e-14 51.0 39.0 1.3e-13 50.4 39.0 1.2 1 0 0 1 1 1 1 Amino acid permease Glycophorin_A PF01102.18 OAP64286.1 - 0.027 14.7 0.4 0.065 13.5 0.0 1.8 2 0 0 2 2 2 0 Glycophorin A Na_Ca_ex PF01699.24 OAP64287.1 - 3.9e-36 124.3 47.9 1.5e-19 70.5 21.8 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Rib_recp_KP_reg PF05104.12 OAP64287.1 - 0.0057 17.7 10.0 0.0057 17.7 10.0 3.0 2 1 1 3 3 3 1 Ribosome receptor lysine/proline rich region Peptidase_S64 PF08192.11 OAP64287.1 - 8.9 4.7 15.3 14 4.0 15.3 1.2 1 0 0 1 1 1 0 Peptidase family S64 AP3D1 PF06375.11 OAP64287.1 - 9.7 6.4 20.6 6.1 7.1 10.7 2.4 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 HATPase_c PF02518.26 OAP64288.1 - 8.4e-23 81.0 0.0 4.7e-22 78.6 0.0 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 OAP64288.1 - 5e-20 71.8 0.6 1.4e-19 70.3 0.6 1.8 1 0 0 1 1 1 1 Response regulator receiver domain PAS_4 PF08448.10 OAP64288.1 - 1.2e-12 48.0 0.0 8.1e-08 32.5 0.0 3.0 2 0 0 2 2 2 2 PAS fold PAS PF00989.25 OAP64288.1 - 2e-12 47.1 0.1 1.3e-11 44.4 0.0 2.5 3 0 0 3 3 3 1 PAS fold HisKA PF00512.25 OAP64288.1 - 4.4e-09 36.2 1.1 1.8e-08 34.3 0.3 2.4 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.7 OAP64288.1 - 9.3e-09 35.5 0.0 8e-07 29.3 0.0 2.8 2 0 0 2 2 2 1 PAS domain PAS_3 PF08447.12 OAP64288.1 - 1.7e-08 34.6 0.1 4.2e-08 33.4 0.1 1.7 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 OAP64288.1 - 0.011 15.8 0.0 0.041 13.9 0.0 2.0 1 0 0 1 1 1 0 PAS domain dCache_1 PF02743.18 OAP64288.1 - 0.024 14.4 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 Cache domain GAF_2 PF13185.6 OAP64288.1 - 0.043 14.1 0.0 0.5 10.7 0.0 2.4 2 0 0 2 2 2 0 GAF domain GAF_3 PF13492.6 OAP64288.1 - 0.055 13.8 0.0 0.29 11.5 0.0 2.3 1 0 0 1 1 1 0 GAF domain HATPase_c_5 PF14501.6 OAP64288.1 - 0.075 12.9 0.2 0.7 9.8 0.0 2.6 2 0 0 2 2 2 0 GHKL domain MFS_1 PF07690.16 OAP64289.1 - 2.7e-21 75.9 42.9 3.9e-17 62.2 26.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily NUDIX PF00293.28 OAP64290.1 - 8.4e-12 45.3 0.1 1.3e-11 44.7 0.1 1.2 1 0 0 1 1 1 1 NUDIX domain PAP2 PF01569.21 OAP64291.1 - 2.6e-23 82.3 3.3 5.4e-23 81.3 3.3 1.5 1 0 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.6 OAP64291.1 - 0.065 13.8 0.5 0.19 12.3 0.5 1.8 1 0 0 1 1 1 0 PAP2 superfamily C-terminal adh_short_C2 PF13561.6 OAP64293.1 - 4.9e-41 140.8 0.0 5.5e-40 137.4 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP64293.1 - 6.2e-39 133.5 0.1 2.2e-37 128.4 0.0 2.3 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 OAP64293.1 - 5.8e-08 32.9 0.0 8.2e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 KR domain LDcluster4 PF18306.1 OAP64293.1 - 0.042 13.4 0.1 0.078 12.6 0.1 1.4 1 0 0 1 1 1 0 SLOG cluster4 family SPRY PF00622.28 OAP64294.1 - 1.2e-19 70.6 0.0 1.8e-19 70.0 0.0 1.3 1 0 0 1 1 1 1 SPRY domain DUF3611 PF12263.8 OAP64294.1 - 0.051 13.5 0.1 0.079 12.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3611) Acetyltransf_CG PF14542.6 OAP64295.1 - 0.044 13.9 0.0 0.078 13.1 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_7 PF13508.7 OAP64295.1 - 0.081 13.4 0.0 0.11 13.0 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OAP64295.1 - 0.15 12.0 0.0 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PDEase_II PF02112.15 OAP64296.1 - 1.8e-50 172.0 0.0 6e-23 81.5 0.0 3.1 3 0 0 3 3 3 3 cAMP phosphodiesterases class-II Cupin_2 PF07883.11 OAP64297.1 - 1.9e-11 43.5 0.5 1.9e-11 43.5 0.5 2.4 2 1 0 2 2 2 1 Cupin domain Cupin_1 PF00190.22 OAP64297.1 - 8e-08 32.0 0.0 1.2e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.19 OAP64297.1 - 0.0026 17.7 0.1 0.0026 17.7 0.1 2.2 2 0 0 2 2 2 1 AraC-like ligand binding domain Pirin PF02678.16 OAP64297.1 - 0.024 14.6 0.1 0.024 14.6 0.1 1.7 2 0 0 2 2 2 0 Pirin FdtA PF05523.11 OAP64297.1 - 0.035 13.8 0.0 0.067 12.9 0.0 1.4 1 0 0 1 1 1 0 WxcM-like, C-terminal GPI PF06560.11 OAP64297.1 - 0.15 11.3 0.2 0.24 10.7 0.2 1.4 1 1 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) COesterase PF00135.28 OAP64298.1 - 3.7e-74 250.4 0.0 5e-74 250.0 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAP64298.1 - 0.00021 21.2 0.7 0.00061 19.7 0.1 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold SLAC1 PF03595.17 OAP64299.1 - 3.6e-79 266.4 53.3 4.1e-79 266.2 53.3 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Rad1 PF02144.16 OAP64300.1 - 1.1e-77 260.9 0.0 1.2e-77 260.6 0.0 1.0 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Ost5 PF05251.12 OAP64301.1 - 6.5e-19 68.0 7.3 7.5e-19 67.8 7.3 1.1 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit 5 NADH5_C PF06455.11 OAP64301.1 - 0.0097 15.5 0.2 0.0097 15.5 0.2 1.0 1 0 0 1 1 1 1 NADH dehydrogenase subunit 5 C-terminus TCR_zetazeta PF11628.8 OAP64301.1 - 0.032 13.9 0.6 0.072 12.8 0.6 1.6 1 0 0 1 1 1 0 T-cell surface glycoprotein CD3 zeta chain Ni_hydr_CYTB PF01292.20 OAP64301.1 - 0.035 13.7 0.3 0.035 13.7 0.3 1.0 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 Bromodomain PF00439.25 OAP64303.1 - 7.6e-26 90.0 2.2 9.8e-26 89.6 0.7 1.9 2 0 0 2 2 2 1 Bromodomain Acetyltransf_1 PF00583.25 OAP64303.1 - 2.1e-08 34.4 0.0 3.9e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OAP64303.1 - 1.4e-06 28.3 0.0 2.4e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OAP64303.1 - 0.00033 21.0 0.1 0.00056 20.3 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF4218 PF13960.6 OAP64303.1 - 0.1 12.2 0.0 0.28 10.8 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) RGS PF00615.19 OAP64304.1 - 2.2e-12 47.3 0.0 4.6e-09 36.6 0.0 2.2 2 0 0 2 2 2 2 Regulator of G protein signaling domain E1-E2_ATPase PF00122.20 OAP64306.1 - 2.9e-51 173.6 1.0 2.9e-51 173.6 1.0 2.5 2 0 0 2 2 2 1 E1-E2 ATPase HMA PF00403.26 OAP64306.1 - 4e-47 158.5 0.3 4e-12 46.4 0.0 4.4 4 0 0 4 4 4 4 Heavy-metal-associated domain Hydrolase PF00702.26 OAP64306.1 - 8e-37 127.6 0.1 2.3e-36 126.0 0.1 1.9 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 OAP64306.1 - 0.0016 18.3 0.8 0.056 13.2 0.2 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase B12-binding PF02310.19 OAP64306.1 - 0.002 18.2 1.9 2.9 7.9 0.0 4.6 5 0 0 5 5 5 1 B12 binding domain DUF1884 PF08967.10 OAP64306.1 - 0.03 14.6 2.1 1.5 9.2 0.1 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF1884) PaaX PF07848.12 OAP64306.1 - 0.14 12.4 2.6 35 4.7 0.0 4.4 5 0 0 5 5 5 0 PaaX-like protein MFS_1 PF07690.16 OAP64307.1 - 1.9e-23 83.0 36.0 1.9e-23 83.0 36.0 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily GMC_oxred_N PF00732.19 OAP64308.1 - 5.6e-57 193.4 0.0 7.8e-57 192.9 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAP64308.1 - 8.1e-32 110.7 0.1 1.5e-31 109.9 0.1 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 OAP64308.1 - 0.0021 17.2 0.4 0.0037 16.4 0.2 1.4 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 OAP64308.1 - 0.0071 15.5 1.7 0.041 13.0 0.7 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.6 OAP64308.1 - 0.011 15.1 0.1 2.6 7.2 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAP64308.1 - 0.011 16.0 2.5 0.012 15.8 0.8 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAP64308.1 - 0.077 12.6 3.3 1.7 8.1 3.3 2.5 1 1 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.17 OAP64308.1 - 0.1 11.8 0.1 0.21 10.8 0.1 1.4 1 0 0 1 1 1 0 Thi4 family Aldo_ket_red PF00248.21 OAP64309.1 - 1.5e-44 152.4 0.0 2.6e-44 151.6 0.0 1.3 1 1 0 1 1 1 1 Aldo/keto reductase family UQ_con PF00179.26 OAP64310.1 - 3.5e-47 159.6 0.0 4.4e-47 159.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 OAP64310.1 - 0.00013 22.2 0.1 0.00028 21.1 0.1 1.8 1 1 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 OAP64310.1 - 0.012 15.3 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B UFC1 PF08694.11 OAP64310.1 - 0.026 14.2 0.1 0.051 13.2 0.1 1.6 1 1 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 UEV PF05743.13 OAP64310.1 - 0.031 14.1 0.0 0.046 13.6 0.0 1.4 1 0 0 1 1 1 0 UEV domain Pkinase PF00069.25 OAP64311.1 - 1.4e-56 191.8 0.0 2.1e-56 191.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP64311.1 - 3e-24 85.7 0.0 4.4e-24 85.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAP64311.1 - 1.5e-09 37.6 0.0 2.2e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OAP64311.1 - 0.0049 16.2 0.1 0.011 15.1 0.0 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OAP64311.1 - 0.067 13.1 0.1 0.4 10.5 0.0 2.1 2 1 0 2 2 2 0 Phosphotransferase enzyme family SCP2 PF02036.17 OAP64312.1 - 2.3e-23 82.6 0.5 2.7e-23 82.4 0.5 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 OAP64312.1 - 1.7e-06 28.3 0.1 2e-06 28.1 0.1 1.1 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal SCP2_2 PF13530.6 OAP64312.1 - 0.01 16.2 0.0 0.013 15.9 0.0 1.3 1 0 0 1 1 1 0 Sterol carrier protein domain Hva1_TUDOR PF11160.8 OAP64313.1 - 3e-13 49.7 2.3 3e-13 49.7 2.3 2.4 2 1 0 2 2 2 1 Hypervirulence associated proteins TUDOR domain Fungal_trans_2 PF11951.8 OAP64314.1 - 1.7e-07 30.4 0.0 2.6e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain FMO-like PF00743.19 OAP64316.1 - 3e-17 62.2 1.7 2.5e-16 59.2 0.4 2.5 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OAP64316.1 - 2.1e-12 47.1 0.0 1e-11 44.9 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAP64316.1 - 2.1e-07 30.5 0.0 1.5e-05 24.4 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAP64316.1 - 2.5e-06 26.9 0.2 1.6e-05 24.2 0.0 2.3 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 OAP64316.1 - 3.4e-05 23.3 0.2 0.00024 20.5 0.1 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAP64316.1 - 0.0092 16.0 0.0 0.74 9.8 0.0 3.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 OAP64316.1 - 0.06 13.9 0.2 2.8 8.5 0.0 3.1 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase S_locus_glycop PF00954.20 OAP64316.1 - 0.072 13.6 2.5 0.1 13.1 0.2 2.3 2 0 0 2 2 2 0 S-locus glycoprotein domain NACHT_N PF17100.5 OAP64317.1 - 3.5e-16 59.7 3.2 6.5e-16 58.9 3.2 1.4 1 0 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase Ank_2 PF12796.7 OAP64317.1 - 3e-14 53.4 0.0 3e-13 50.2 0.0 2.8 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) NACHT PF05729.12 OAP64317.1 - 1.4e-12 47.8 0.0 3.3e-11 43.4 0.1 2.5 2 0 0 2 2 2 1 NACHT domain Ank_4 PF13637.6 OAP64317.1 - 2.4e-11 43.9 0.0 2.3e-07 31.2 0.0 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAP64317.1 - 2.7e-10 39.6 0.0 0.0013 19.0 0.0 4.6 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 OAP64317.1 - 1.9e-09 37.5 0.1 0.0027 18.1 0.0 4.1 4 0 0 4 4 3 2 Ankyrin repeat Ank_5 PF13857.6 OAP64317.1 - 2.1e-08 34.2 0.0 0.0004 20.6 0.0 4.0 2 1 2 4 4 4 3 Ankyrin repeats (many copies) AAA_16 PF13191.6 OAP64317.1 - 8.3e-08 32.8 0.1 5.5e-07 30.1 0.1 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 OAP64317.1 - 0.0023 18.2 0.1 0.015 15.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain KAP_NTPase PF07693.14 OAP64317.1 - 0.013 14.8 0.2 0.034 13.4 0.1 1.7 1 1 0 1 1 1 0 KAP family P-loop domain RNA_helicase PF00910.22 OAP64317.1 - 0.017 15.5 0.0 0.073 13.5 0.0 2.1 1 0 0 1 1 1 0 RNA helicase P53_TAD PF08563.11 OAP64317.1 - 0.18 11.3 1.0 0.48 10.0 1.0 1.7 1 0 0 1 1 1 0 P53 transactivation motif SRP19 PF01922.17 OAP64318.1 - 1.3e-23 83.7 0.0 1.9e-23 83.2 0.0 1.2 1 0 0 1 1 1 1 SRP19 protein NAM-associated PF14303.6 OAP64319.1 - 0.92 10.2 7.8 1.4 9.6 7.8 1.3 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain BTB PF00651.31 OAP64320.1 - 0.00089 19.5 0.0 0.0017 18.6 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Fungal_trans PF04082.18 OAP64322.1 - 1.6e-17 63.5 0.3 3e-17 62.5 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Methyltr_RsmB-F PF01189.17 OAP64323.1 - 2.6e-19 69.6 0.1 2.2e-12 47.0 0.1 2.4 2 0 0 2 2 2 2 16S rRNA methyltransferase RsmB/F PBP1_TM PF14812.6 OAP64323.1 - 0.12 12.8 0.3 0.31 11.4 0.3 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NDUF_B4 PF07225.12 OAP64324.1 - 0.0096 15.8 0.1 0.011 15.6 0.1 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) GST_N PF02798.20 OAP64325.1 - 1.6e-12 47.6 0.0 3.5e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OAP64325.1 - 3.7e-09 36.7 0.0 7e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OAP64325.1 - 4.7e-09 36.4 0.0 7.7e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OAP64325.1 - 3.5e-08 33.3 0.0 7.1e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OAP64325.1 - 1.5e-07 31.6 0.0 2.5e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 OAP64325.1 - 2e-07 31.3 0.0 4.3e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_5 PF16865.5 OAP64325.1 - 0.015 15.8 0.0 0.049 14.2 0.0 1.8 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain BTB_2 PF02214.22 OAP64326.1 - 5.6e-07 29.8 0.0 0.003 17.9 0.0 2.4 2 0 0 2 2 2 2 BTB/POZ domain DEAD PF00270.29 OAP64327.1 - 7.3e-33 113.8 0.1 2.5e-15 56.7 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 OAP64327.1 - 1e-18 67.7 0.0 3.8e-18 65.9 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAP64327.1 - 9.2e-08 32.3 1.0 1.5e-06 28.3 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 OAP64327.1 - 0.095 11.5 0.0 0.45 9.2 0.0 1.9 2 0 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Nop25 PF09805.9 OAP64327.1 - 2.8 8.4 16.8 0.27 11.7 10.7 2.2 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) PIGA PF08288.12 OAP64328.1 - 3.8e-45 152.4 2.1 3.8e-45 152.4 2.1 1.9 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glyco_transf_4 PF13439.6 OAP64328.1 - 1.7e-29 103.0 0.6 2.7e-29 102.3 0.6 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 OAP64328.1 - 1.2e-27 96.5 0.0 1.9e-27 95.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 OAP64328.1 - 3.8e-24 85.6 0.2 8.1e-24 84.6 0.2 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 OAP64328.1 - 7.7e-12 45.9 0.0 1.5e-11 45.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 OAP64328.1 - 3.9e-06 27.0 0.2 1.1e-05 25.5 0.1 1.7 2 0 0 2 2 2 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.6 OAP64328.1 - 0.0061 16.9 0.0 0.031 14.7 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 OAP64328.1 - 0.07 12.8 0.0 0.4 10.3 0.0 2.1 2 0 0 2 2 2 0 Starch synthase catalytic domain ECH_1 PF00378.20 OAP64329.1 - 1.4e-22 80.3 0.0 3.3e-20 72.5 0.0 2.9 2 1 0 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAP64329.1 - 5.4e-08 32.7 0.0 8.9e-06 25.4 0.0 2.5 3 0 0 3 3 3 2 Enoyl-CoA hydratase/isomerase Palm_thioest PF02089.15 OAP64331.1 - 2.2e-07 31.0 0.0 3.2e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_6 PF12697.7 OAP64331.1 - 1.7e-05 25.6 1.0 3.2e-05 24.7 1.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.14 OAP64331.1 - 6.1e-05 22.6 0.0 0.00012 21.7 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 OAP64331.1 - 0.00012 21.8 0.0 0.00029 20.6 0.0 1.6 2 0 0 2 2 2 1 PGAP1-like protein Abhydrolase_1 PF00561.20 OAP64331.1 - 0.005 16.5 0.3 0.068 12.8 0.1 2.4 1 1 1 2 2 2 1 alpha/beta hydrolase fold Lipase_2 PF01674.18 OAP64331.1 - 0.12 11.9 0.0 0.32 10.5 0.0 1.7 1 0 0 1 1 1 0 Lipase (class 2) LCAT PF02450.15 OAP64331.1 - 0.13 11.4 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase V-ATPase_G PF03179.15 OAP64332.1 - 3.3e-32 111.1 18.1 3.8e-32 111.0 18.1 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit V-ATPase_G_2 PF16999.5 OAP64332.1 - 0.023 15.1 16.7 0.034 14.5 16.7 1.3 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit ATP-synt_B PF00430.18 OAP64332.1 - 0.1 12.7 22.3 0.043 13.9 13.4 2.1 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) ATP11 PF06644.11 OAP64332.1 - 0.13 12.0 12.1 0.15 11.8 12.1 1.0 1 0 0 1 1 1 0 ATP11 protein OmpH PF03938.14 OAP64332.1 - 0.2 12.0 17.5 0.26 11.6 17.5 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) RGS-like PF09128.11 OAP64332.1 - 0.23 11.2 5.2 0.24 11.1 5.2 1.2 1 0 0 1 1 1 0 Regulator of G protein signalling-like domain Vfa1 PF08432.10 OAP64332.1 - 0.94 9.8 13.9 1.1 9.5 13.9 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF3552 PF12072.8 OAP64332.1 - 1 8.8 23.0 4 6.8 22.8 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) SAPS PF04499.15 OAP64332.1 - 1.8 7.3 8.7 2 7.1 8.7 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RRF PF01765.19 OAP64332.1 - 1.8 8.5 18.5 4.5 7.2 18.7 1.6 1 1 1 2 2 2 0 Ribosome recycling factor TMPIT PF07851.13 OAP64332.1 - 6.2 6.0 7.6 6.9 5.8 7.6 1.0 1 0 0 1 1 1 0 TMPIT-like protein DUF3987 PF13148.6 OAP64332.1 - 8.5 5.3 9.2 10 5.0 9.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) PET117 PF15786.5 OAP64333.1 - 1.3e-24 86.2 2.2 1.5e-24 86.0 2.2 1.0 1 0 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial HD_4 PF13328.6 OAP64333.1 - 0.011 15.5 0.2 0.013 15.2 0.2 1.2 1 0 0 1 1 1 0 HD domain DUF2615 PF11027.8 OAP64334.1 - 0.037 14.2 0.0 0.079 13.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2615) VSG_B PF13206.6 OAP64334.1 - 0.06 12.6 0.3 0.11 11.7 0.3 1.3 1 0 0 1 1 1 0 Trypanosomal VSG domain Spt20 PF12090.8 OAP64334.1 - 0.32 10.6 3.0 0.43 10.1 3.0 1.2 1 0 0 1 1 1 0 Spt20 family Sel1 PF08238.12 OAP64335.1 - 1.3e-25 89.2 37.8 1.3e-06 28.9 0.3 9.4 12 0 0 12 12 12 5 Sel1 repeat TPR_7 PF13176.6 OAP64335.1 - 0.0081 16.1 2.8 1.4 9.1 0.0 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_4 PF07721.14 OAP64335.1 - 0.051 14.2 0.2 6.7 7.7 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 OAP64335.1 - 0.13 12.5 12.9 15 6.0 0.0 7.3 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_8 PF13181.6 OAP64335.1 - 0.47 10.8 4.8 24 5.5 0.0 4.9 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF1771 PF08590.10 OAP64335.1 - 0.59 10.6 4.6 17 5.8 0.1 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF1771) TPR_16 PF13432.6 OAP64335.1 - 6.6 7.5 11.2 7 7.4 1.4 4.2 3 1 1 4 4 4 0 Tetratricopeptide repeat FAD_binding_3 PF01494.19 OAP64337.1 - 3.4e-17 62.7 0.0 7.5e-17 61.6 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 OAP64337.1 - 4.2e-07 29.5 0.0 8.4e-07 28.5 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAP64337.1 - 3.2e-05 24.1 0.1 0.00011 22.4 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAP64337.1 - 6.6e-05 22.6 0.9 0.062 12.9 0.4 2.6 1 1 1 2 2 2 2 FAD dependent oxidoreductase GIDA PF01134.22 OAP64337.1 - 0.00019 20.7 0.1 0.028 13.5 0.1 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox PF00070.27 OAP64337.1 - 0.00041 20.9 0.3 0.0036 17.8 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAP64337.1 - 0.00095 18.3 0.6 0.0016 17.6 0.6 1.4 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 OAP64337.1 - 0.0012 18.2 0.1 0.0028 17.0 0.1 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 OAP64337.1 - 0.0032 16.8 0.2 0.05 12.8 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAP64337.1 - 0.015 14.0 0.5 0.066 11.9 0.1 2.0 2 0 0 2 2 2 0 HI0933-like protein Wtap PF17098.5 OAP64337.1 - 0.17 11.8 0.0 0.43 10.5 0.0 1.6 1 0 0 1 1 1 0 WTAP/Mum2p family Trp_halogenase PF04820.14 OAP64337.1 - 0.17 10.7 0.1 2.8 6.7 0.1 2.0 2 0 0 2 2 2 0 Tryptophan halogenase Thi4 PF01946.17 OAP64337.1 - 0.18 11.0 0.1 1.1 8.5 0.1 2.0 2 0 0 2 2 2 0 Thi4 family Aldedh PF00171.22 OAP64338.1 - 8.1e-163 542.2 0.1 9.1e-163 542.0 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family ELO PF01151.18 OAP64339.1 - 3.8e-08 33.2 11.5 1.2e-07 31.6 11.6 1.6 1 1 0 1 1 1 1 GNS1/SUR4 family RINT1_TIP1 PF04437.13 OAP64340.1 - 3.3e-159 531.0 0.0 1.4e-158 528.9 0.0 1.9 2 0 0 2 2 2 1 RINT-1 / TIP-1 family SPATA24 PF15175.6 OAP64340.1 - 0.06 13.2 7.3 0.11 12.4 7.3 1.4 1 0 0 1 1 1 0 Spermatogenesis-associated protein 24 Prominin PF05478.11 OAP64340.1 - 0.14 10.0 6.8 0.23 9.3 6.8 1.3 1 0 0 1 1 1 0 Prominin Clusterin PF01093.17 OAP64340.1 - 0.15 11.0 7.2 0.15 11.1 4.8 2.0 2 0 0 2 2 2 0 Clusterin WASH-7_mid PF14744.6 OAP64340.1 - 0.54 9.3 3.7 0.99 8.4 3.7 1.4 1 0 0 1 1 1 0 WASH complex subunit 7 DUF4407 PF14362.6 OAP64340.1 - 0.73 9.1 10.2 1.3 8.3 10.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MbeB_N PF04837.12 OAP64340.1 - 1 9.7 3.5 4 7.8 0.1 2.8 2 0 0 2 2 2 0 MbeB-like, N-term conserved region GP41 PF00517.17 OAP64340.1 - 3.8 7.4 7.4 7.4 6.4 7.4 1.4 1 0 0 1 1 1 0 Retroviral envelope protein Macoilin PF09726.9 OAP64340.1 - 6.1 5.3 12.3 8.9 4.7 12.3 1.1 1 0 0 1 1 1 0 Macoilin family DNA_ligase_A_M PF01068.21 OAP64341.1 - 2.6e-51 174.2 0.4 1.5e-48 165.2 0.0 2.3 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 OAP64341.1 - 8.6e-36 123.9 0.0 1.7e-35 122.9 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 OAP64341.1 - 5.4e-20 71.8 0.0 3e-19 69.5 0.0 2.4 3 0 0 3 3 3 1 ATP dependent DNA ligase C terminal region Amidase PF01425.21 OAP64342.1 - 2.2e-77 260.9 0.0 2.5e-76 257.5 0.0 1.9 1 1 0 1 1 1 1 Amidase adh_short PF00106.25 OAP64343.1 - 1.2e-21 77.1 0.0 4e-19 68.8 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAP64343.1 - 9.3e-13 48.3 0.0 5.9e-10 39.1 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP64343.1 - 4.4e-11 43.0 0.1 6.7e-11 42.4 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAP64343.1 - 2.2e-06 27.3 0.0 3.5e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 OAP64343.1 - 0.0043 16.2 0.0 0.008 15.4 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 OAP64343.1 - 0.014 14.8 0.0 0.04 13.3 0.0 1.7 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase Methyltransf_25 PF13649.6 OAP64343.1 - 0.15 12.8 0.0 0.28 11.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Pkinase PF00069.25 OAP64344.1 - 5e-21 75.3 0.0 8.5e-21 74.5 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP64344.1 - 2.3e-18 66.4 0.1 1.3e-17 64.0 0.1 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAP64344.1 - 2.3e-05 23.9 0.0 6.2e-05 22.4 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OAP64344.1 - 0.02 13.7 0.0 0.03 13.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 OAP64344.1 - 0.024 14.0 0.0 0.038 13.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family WaaY PF06176.11 OAP64344.1 - 0.024 14.2 0.0 0.036 13.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Opi1 PF08618.10 OAP64346.1 - 0.021 14.1 0.4 7.3 5.7 0.0 2.9 3 0 0 3 3 3 0 Transcription factor Opi1 GSH-S_N PF02951.14 OAP64346.1 - 0.038 14.1 0.2 0.091 12.9 0.2 1.6 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, N-terminal domain Jnk-SapK_ap_N PF09744.9 OAP64346.1 - 0.11 12.7 2.2 0.21 11.8 2.2 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Abhydrolase_6 PF12697.7 OAP64347.1 - 8.5e-06 26.5 0.3 1.2e-05 26.1 0.3 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAP64347.1 - 0.0012 18.6 0.1 0.0022 17.7 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold DnaJ PF00226.31 OAP64348.1 - 1.4e-15 57.1 0.4 3.6e-15 55.8 0.4 1.7 1 0 0 1 1 1 1 DnaJ domain Sec63 PF02889.16 OAP64348.1 - 5.5e-07 29.0 0.0 0.00023 20.4 0.0 2.3 2 0 0 2 2 2 2 Sec63 Brl domain LZ_Tnp_IS66 PF13007.7 OAP64348.1 - 0.13 13.0 1.5 40 5.1 0.0 3.4 3 0 0 3 3 3 0 Transposase C of IS166 homeodomain Oxysterol_BP PF01237.18 OAP64349.1 - 1.1e-90 304.3 0.3 4.4e-88 295.6 0.3 2.3 1 1 0 1 1 1 1 Oxysterol-binding protein DUF3605 PF12239.8 OAP64349.1 - 2.6e-46 157.7 0.5 6.4e-46 156.5 0.5 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) Isochorismatase PF00857.20 OAP64350.1 - 7.2e-21 75.1 0.0 1.3e-20 74.3 0.0 1.4 1 1 0 1 1 1 1 Isochorismatase family TFIIA PF03153.13 OAP64351.1 - 1.5e-60 206.3 5.3 2.3e-60 205.8 5.3 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Bap31 PF05529.12 OAP64352.1 - 6.5e-48 162.0 8.6 1.1e-47 161.3 8.6 1.3 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 OAP64352.1 - 3.2e-16 59.0 9.4 6.1e-16 58.2 9.4 1.5 1 0 0 1 1 1 1 Bap31/Bap29 cytoplasmic coiled-coil domain Mod_r PF07200.13 OAP64352.1 - 0.0034 17.5 2.7 0.0052 16.9 2.7 1.3 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein DUF4337 PF14235.6 OAP64352.1 - 0.0065 16.6 3.1 0.013 15.6 3.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4337) Cep57_MT_bd PF06657.13 OAP64352.1 - 0.0077 16.7 2.7 0.059 13.8 0.3 2.5 1 1 1 2 2 2 1 Centrosome microtubule-binding domain of Cep57 T3SSipB PF16535.5 OAP64352.1 - 0.011 16.2 1.0 0.016 15.7 1.0 1.2 1 0 0 1 1 1 0 Type III cell invasion protein SipB DUF4047 PF13256.6 OAP64352.1 - 0.015 15.5 1.5 0.024 14.8 1.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) YabA PF06156.13 OAP64352.1 - 0.033 14.8 0.7 0.062 13.9 0.7 1.5 1 0 0 1 1 1 0 Initiation control protein YabA DivIC PF04977.15 OAP64352.1 - 0.093 12.5 6.1 2.2 8.1 4.2 2.7 2 0 0 2 2 2 0 Septum formation initiator Spc7 PF08317.11 OAP64352.1 - 0.1 11.5 3.4 0.14 11.1 3.4 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Spc24 PF08286.11 OAP64352.1 - 0.15 12.3 2.1 0.27 11.5 2.1 1.4 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 bZIP_Maf PF03131.17 OAP64352.1 - 0.18 12.3 2.9 0.3 11.6 2.9 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor KELK PF15796.5 OAP64352.1 - 0.41 11.1 6.9 1.1 9.8 6.9 1.7 1 1 0 1 1 1 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase COesterase PF00135.28 OAP64353.1 - 3.8e-78 263.6 0.1 5.8e-78 263.0 0.1 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAP64353.1 - 0.0011 18.9 1.3 0.018 14.9 0.8 2.7 2 1 0 2 2 2 1 alpha/beta hydrolase fold PhoD PF09423.10 OAP64354.1 - 5e-114 381.0 4.8 6.4e-114 380.6 4.8 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase PhoD_N PF16655.5 OAP64354.1 - 2.2e-33 114.7 0.1 5.4e-33 113.4 0.1 1.7 1 0 0 1 1 1 1 PhoD-like phosphatase, N-terminal domain Pur_ac_phosph_N PF16656.5 OAP64354.1 - 0.00028 21.4 2.8 0.00038 21.0 0.7 2.3 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain NUDIX PF00293.28 OAP64355.1 - 3.6e-18 65.9 0.4 9.6e-18 64.5 0.4 1.7 1 1 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 OAP64355.1 - 0.16 12.0 0.7 0.67 10.0 0.7 2.1 1 1 0 1 1 1 0 NUDIX domain FYVE PF01363.21 OAP64356.1 - 4.8e-16 58.6 6.9 7e-16 58.1 6.9 1.2 1 0 0 1 1 1 1 FYVE zinc finger zf-AN1 PF01428.16 OAP64356.1 - 0.11 12.7 14.0 0.072 13.3 10.2 2.1 2 0 0 2 2 2 0 AN1-like Zinc finger Prp18 PF02840.15 OAP64357.1 - 2e-52 177.0 0.0 2e-52 177.0 0.0 1.9 2 0 0 2 2 2 1 Prp18 domain PRP4 PF08799.11 OAP64357.1 - 8.7e-10 38.0 1.2 8.7e-10 38.0 1.2 3.4 3 1 1 4 4 4 1 pre-mRNA processing factor 4 (PRP4) like GalP_UDP_tr_C PF02744.17 OAP64357.1 - 0.042 13.6 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 Galactose-1-phosphate uridyl transferase, C-terminal domain CCDC71L PF15374.6 OAP64357.1 - 0.078 12.2 6.0 0.13 11.5 6.0 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 71L TFIIA PF03153.13 OAP64357.1 - 1.3 9.0 5.8 2 8.3 5.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit eIF3_subunit PF08597.10 OAP64357.1 - 5.3 6.9 17.4 10 5.9 17.4 1.5 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Presenilin PF01080.17 OAP64357.1 - 9.6 4.9 6.4 14 4.3 6.4 1.2 1 0 0 1 1 1 0 Presenilin cNMP_binding PF00027.29 OAP64358.1 - 1.4e-36 124.5 0.0 2.1e-21 75.8 0.0 2.7 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain cNMPbd_u2 PF16643.5 OAP64358.1 - 1.8e-32 113.0 12.7 1.8e-32 113.0 12.7 2.4 2 0 0 2 2 2 1 Unstructured region on cNMP-binding protein LRR_6 PF13516.6 OAP64358.1 - 5.7e-07 29.1 6.3 1.8 8.8 0.0 8.1 9 0 0 9 9 9 2 Leucine Rich repeat LRR_4 PF12799.7 OAP64358.1 - 2.6e-06 27.7 7.0 0.045 14.2 0.1 7.0 6 1 2 9 9 9 1 Leucine Rich repeats (2 copies) F-box-like PF12937.7 OAP64358.1 - 0.00011 22.0 0.8 0.00025 20.9 0.1 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 OAP64358.1 - 0.017 15.0 4.2 0.036 14.0 0.0 3.5 3 0 0 3 3 3 0 F-box domain LRR_1 PF00560.33 OAP64358.1 - 6.4 7.7 18.5 14 6.7 0.4 7.4 8 1 0 8 8 8 0 Leucine Rich Repeat Tim17 PF02466.19 OAP64359.1 - 0.00028 21.2 2.9 0.00042 20.7 2.9 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Abhydrolase_6 PF12697.7 OAP64361.1 - 0.031 14.9 0.0 0.031 14.9 0.0 2.5 2 1 0 2 2 2 0 Alpha/beta hydrolase family TAN PF11640.8 OAP64361.1 - 0.1 12.7 0.9 0.91 9.6 0.1 2.4 2 0 0 2 2 2 0 Telomere-length maintenance and DNA damage repair HEPN_DZIP3 PF18738.1 OAP64361.1 - 3.2 7.5 7.4 7.8 6.2 0.1 2.7 2 0 0 2 2 2 0 DZIP3/ hRUL138-like HEPN Fungal_trans_2 PF11951.8 OAP64362.1 - 9.6e-06 24.6 0.0 4.3e-05 22.5 0.0 1.9 1 1 0 2 2 2 1 Fungal specific transcription factor domain GST_C PF00043.25 OAP64363.1 - 8.3e-08 32.4 0.0 1.5e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 OAP64363.1 - 3.5e-07 30.4 0.0 8.1e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 OAP64363.1 - 4.8e-07 30.0 0.0 9.6e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 OAP64363.1 - 2.8e-06 27.5 0.0 7.2e-06 26.1 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 OAP64363.1 - 0.0005 20.4 0.0 0.00085 19.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAP64363.1 - 0.00084 19.3 0.0 0.0014 18.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain A_deaminase PF00962.22 OAP64364.1 - 1.7e-65 221.5 0.0 1.1e-44 153.1 0.0 2.0 1 1 1 2 2 2 2 Adenosine/AMP deaminase POR PF01558.18 OAP64364.1 - 0.029 14.5 0.0 0.043 13.9 0.0 1.2 1 0 0 1 1 1 0 Pyruvate ferredoxin/flavodoxin oxidoreductase DUF1655 PF07868.11 OAP64364.1 - 0.084 12.9 0.3 2 8.5 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1655) DUF2063 PF09836.9 OAP64364.1 - 0.11 12.7 0.1 0.23 11.7 0.1 1.4 1 0 0 1 1 1 0 Putative DNA-binding domain LCAT PF02450.15 OAP64365.1 - 0.033 13.4 0.0 0.055 12.6 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Hydrolase_4 PF12146.8 OAP64365.1 - 0.048 12.9 0.0 0.088 12.1 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF676 PF05057.14 OAP64365.1 - 0.05 13.1 0.0 0.087 12.3 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Pkinase PF00069.25 OAP64367.1 - 2.7e-48 164.6 0.0 7.6e-48 163.2 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP64367.1 - 3e-18 66.0 0.0 1.1e-17 64.2 0.0 1.9 2 1 0 2 2 2 1 Protein tyrosine kinase TAF4 PF05236.14 OAP64368.1 - 1.2e-25 90.8 11.9 1.5e-22 80.7 11.8 2.5 2 1 0 2 2 2 2 Transcription initiation factor TFIID component TAF4 family PP2C PF00481.21 OAP64368.1 - 0.25 10.9 3.3 5.6 6.5 1.0 2.3 2 0 0 2 2 2 0 Protein phosphatase 2C Rtf2 PF04641.12 OAP64368.1 - 1.5 8.1 6.3 2.8 7.2 6.3 1.4 1 0 0 1 1 1 0 Rtf2 RING-finger CPSF73-100_C PF11718.8 OAP64369.1 - 2.5e-80 269.1 0.0 3.5e-80 268.6 0.0 1.2 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 OAP64369.1 - 2.2e-29 101.9 0.0 4.7e-29 100.9 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.27 OAP64369.1 - 9.5e-19 68.2 0.3 2.1e-18 67.0 0.3 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 OAP64369.1 - 5.3e-18 65.1 0.1 9.4e-18 64.3 0.1 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain RMMBL PF07521.12 OAP64369.1 - 1e-10 41.4 0.0 2e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_3 PF13483.6 OAP64369.1 - 6.6e-06 26.1 0.2 4.3e-05 23.5 0.0 2.3 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 OAP64369.1 - 6.8e-05 22.5 0.4 6.8e-05 22.5 0.4 1.8 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Ribosomal_L28 PF00830.19 OAP64369.1 - 0.17 12.1 0.0 0.38 11.0 0.0 1.6 1 0 0 1 1 1 0 Ribosomal L28 family adh_short PF00106.25 OAP64370.1 - 6.9e-28 97.4 0.0 4.9e-13 49.0 0.2 2.3 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAP64370.1 - 1.2e-17 64.3 2.9 4.4e-09 36.3 1.4 2.3 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase 3Beta_HSD PF01073.19 OAP64370.1 - 0.066 12.2 0.0 0.094 11.7 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 OAP64370.1 - 0.079 12.9 0.3 0.89 9.4 0.0 2.4 2 1 0 2 2 2 0 KR domain HEAT PF02985.22 OAP64371.1 - 9.8e-16 56.5 9.3 0.00037 20.5 0.1 9.2 9 0 0 9 9 9 2 HEAT repeat HEAT_2 PF13646.6 OAP64371.1 - 7e-10 39.2 6.5 0.0017 18.7 0.1 6.1 4 2 2 7 7 7 4 HEAT repeats IBN_N PF03810.19 OAP64371.1 - 9.6e-10 38.2 0.7 1e-08 35.0 0.1 3.1 3 0 0 3 3 3 1 Importin-beta N-terminal domain HEAT_EZ PF13513.6 OAP64371.1 - 3.3e-05 24.3 0.0 3.3e-05 24.3 0.0 7.5 8 3 2 10 10 10 1 HEAT-like repeat Cnd1 PF12717.7 OAP64371.1 - 0.0016 18.5 0.3 0.021 14.9 0.0 2.9 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Cse1 PF08506.10 OAP64371.1 - 0.02 13.7 0.0 12 4.6 0.1 3.2 3 0 0 3 3 3 0 Cse1 CLASP_N PF12348.8 OAP64371.1 - 0.022 14.3 1.4 19 4.7 0.0 4.6 3 1 1 5 5 5 0 CLASP N terminal NUC173 PF08161.12 OAP64371.1 - 0.42 10.2 2.0 3.9 7.1 0.2 3.2 3 0 0 3 3 3 0 NUC173 domain Arm PF00514.23 OAP64371.1 - 0.52 10.4 10.9 2.5 8.3 0.0 5.5 7 0 0 7 7 7 0 Armadillo/beta-catenin-like repeat ANAPC4 PF12896.7 OAP64372.1 - 9.6e-54 182.0 0.0 1.5e-53 181.3 0.0 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 ANAPC4_WD40 PF12894.7 OAP64372.1 - 4.9e-16 58.8 0.0 1.2e-15 57.6 0.0 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OAP64372.1 - 0.12 13.2 0.0 1.1 10.2 0.0 2.6 2 0 0 2 2 2 0 WD domain, G-beta repeat DUF957 PF06117.11 OAP64372.1 - 0.16 11.6 0.0 1 9.0 0.0 2.4 2 0 0 2 2 2 0 Enterobacterial protein of unknown function (DUF957) AMPK1_CBM PF16561.5 OAP64373.1 - 0.0084 16.3 0.0 0.19 12.0 0.0 2.4 2 0 0 2 2 2 1 Glycogen recognition site of AMP-activated protein kinase Turandot PF07240.11 OAP64373.1 - 0.22 11.5 0.1 0.85 9.6 0.1 1.9 2 0 0 2 2 2 0 Stress-inducible humoral factor Turandot Peptidase_M14 PF00246.24 OAP64374.1 - 1.1e-69 235.4 0.0 1.4e-69 235.1 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase TCTP PF00838.17 OAP64375.1 - 3.3e-59 199.9 2.2 3.7e-59 199.8 2.2 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein Ribosomal_S20p PF01649.18 OAP64375.1 - 0.057 14.1 1.5 0.085 13.5 1.5 1.2 1 0 0 1 1 1 0 Ribosomal protein S20 FDX-ACB PF03147.14 OAP64375.1 - 0.088 13.2 0.3 9.9 6.7 0.0 2.2 1 1 1 2 2 2 0 Ferredoxin-fold anticodon binding domain FA_hydroxylase PF04116.13 OAP64376.1 - 3.5e-22 79.2 14.8 3.5e-22 79.2 14.8 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Lactamase_B_4 PF13691.6 OAP64378.1 - 4e-24 84.1 0.1 4e-22 77.7 0.1 2.5 2 0 0 2 2 2 2 tRNase Z endonuclease Lactamase_B_2 PF12706.7 OAP64378.1 - 1.8e-12 47.2 0.3 4.1e-11 42.8 0.3 2.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 OAP64378.1 - 0.00018 21.6 0.0 0.00051 20.1 0.0 1.7 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily bZIP_1 PF00170.21 OAP64379.1 - 4.4e-09 36.3 16.0 4.9e-09 36.1 12.6 2.5 2 1 0 2 2 2 1 bZIP transcription factor PilO PF04350.13 OAP64379.1 - 0.0019 18.4 2.3 0.0019 18.4 2.3 2.6 3 0 0 3 3 3 1 Pilus assembly protein, PilO bZIP_2 PF07716.15 OAP64379.1 - 0.0037 17.3 15.4 0.0037 17.3 15.4 2.5 2 1 0 2 2 2 1 Basic region leucine zipper Chibby PF14645.6 OAP64379.1 - 0.022 15.2 2.5 0.085 13.3 2.6 2.0 1 1 0 1 1 1 0 Chibby family bZIP_Maf PF03131.17 OAP64379.1 - 0.022 15.3 9.5 0.022 15.3 9.5 2.6 2 0 0 2 2 2 0 bZIP Maf transcription factor FlaC_arch PF05377.11 OAP64379.1 - 0.16 12.3 0.2 0.48 10.9 0.2 1.8 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) V_ATPase_I PF01496.19 OAP64379.1 - 1.2 6.9 7.0 0.082 10.8 1.4 1.7 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DivIC PF04977.15 OAP64379.1 - 2.5 8.0 12.6 0.3 10.9 3.5 2.4 2 0 0 2 2 2 0 Septum formation initiator MctB PF11382.8 OAP64379.1 - 8 6.1 7.8 0.99 9.0 1.1 2.1 2 0 0 2 2 2 0 Copper transport outer membrane protein, MctB MoaC PF01967.21 OAP64380.1 - 5.5e-41 139.8 0.0 1e-40 139.0 0.0 1.5 1 0 0 1 1 1 1 MoaC family Mob_synth_C PF06463.13 OAP64380.1 - 9.3e-37 125.8 2.0 3.1e-36 124.1 0.0 2.7 2 1 1 3 3 3 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 OAP64380.1 - 9.4e-28 97.7 0.1 1.8e-27 96.7 0.1 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 OAP64380.1 - 7.1e-07 29.6 0.0 1.5e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 OAP64380.1 - 0.017 15.3 0.0 0.048 13.8 0.0 1.7 1 0 0 1 1 1 0 4Fe-4S single cluster domain Terminase_2 PF03592.16 OAP64380.1 - 0.18 12.3 0.6 0.55 10.7 0.6 1.8 2 0 0 2 2 2 0 Terminase small subunit F-box-like PF12937.7 OAP64381.1 - 1.5e-08 34.4 0.0 3.2e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 OAP64381.1 - 0.015 15.2 0.1 0.03 14.2 0.1 1.5 1 0 0 1 1 1 0 F-box F-box PF00646.33 OAP64381.1 - 0.032 14.1 0.2 0.087 12.7 0.2 1.7 1 0 0 1 1 1 0 F-box domain PRANC PF09372.10 OAP64381.1 - 0.091 13.1 0.0 0.25 11.7 0.0 1.7 1 0 0 1 1 1 0 PRANC domain Gtr1_RagA PF04670.12 OAP64382.1 - 1.3e-69 234.2 0.4 2e-69 233.5 0.4 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 OAP64382.1 - 3.4e-05 23.4 0.0 6.5e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 OAP64382.1 - 0.00035 20.8 0.0 0.00093 19.4 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 OAP64382.1 - 0.0018 17.9 0.0 0.004 16.7 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OAP64382.1 - 0.0028 17.7 0.0 0.0097 16.0 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 OAP64382.1 - 0.016 15.6 0.0 0.045 14.1 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain SRPRB PF09439.10 OAP64382.1 - 0.016 14.6 0.0 0.045 13.2 0.0 1.7 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit G-alpha PF00503.20 OAP64382.1 - 0.026 13.7 0.8 0.043 13.0 0.8 1.6 1 1 0 1 1 1 0 G-protein alpha subunit Ras PF00071.22 OAP64382.1 - 0.097 12.3 0.1 0.26 10.9 0.1 1.8 1 1 0 1 1 1 0 Ras family Hexapep PF00132.24 OAP64383.1 - 1.5e-06 27.7 12.6 0.027 14.2 3.4 4.3 1 1 3 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.12 OAP64383.1 - 2.9e-06 26.5 0.3 4.6e-06 25.8 0.3 1.2 1 0 0 1 1 1 1 L-fucokinase NTP_transf_3 PF12804.7 OAP64383.1 - 0.00082 19.8 0.0 0.0016 18.8 0.0 1.5 1 0 0 1 1 1 1 MobA-like NTP transferase domain DUF4954 PF16314.5 OAP64383.1 - 0.0039 15.4 1.5 0.0055 14.9 1.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) Hexapep_2 PF14602.6 OAP64383.1 - 6.9 6.5 7.9 6.4 6.6 1.1 2.9 1 1 1 2 2 2 0 Hexapeptide repeat of succinyl-transferase SET PF00856.28 OAP64384.1 - 2.7e-17 63.7 0.7 1.1e-16 61.7 0.3 2.2 2 1 0 2 2 2 1 SET domain Pre-SET PF05033.16 OAP64384.1 - 4.7e-14 53.0 6.7 4.7e-14 53.0 6.7 2.4 2 1 0 2 2 2 1 Pre-SET motif RcsC PF09456.10 OAP64384.1 - 0.15 12.0 0.0 21 5.2 0.0 2.4 2 0 0 2 2 2 0 RcsC Alpha-Beta-Loop (ABL) ASD2 PF08687.11 OAP64385.1 - 0.03 13.9 1.9 0.067 12.7 1.9 1.6 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 bZIP_1 PF00170.21 OAP64385.1 - 0.042 13.9 0.9 0.081 13.0 0.0 1.9 2 0 0 2 2 2 0 bZIP transcription factor DUF2201_N PF13203.6 OAP64385.1 - 3.6 7.1 8.4 0.099 12.2 1.9 1.7 2 0 0 2 2 2 0 Putative metallopeptidase domain Ion_trans PF00520.31 OAP64387.1 - 1.2e-122 407.9 82.3 3e-39 134.7 0.6 4.7 4 1 0 4 4 4 4 Ion transport protein GPHH PF16905.5 OAP64387.1 - 0.00023 20.8 0.0 0.0006 19.5 0.0 1.7 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated EF-hand_1 PF00036.32 OAP64387.1 - 0.00031 20.1 0.0 0.00086 18.7 0.0 1.8 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 OAP64387.1 - 0.0029 17.4 0.0 0.012 15.5 0.0 2.1 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 OAP64387.1 - 0.034 14.6 0.0 0.086 13.3 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain pair PAF-AH_p_II PF03403.13 OAP64389.1 - 2e-41 141.8 0.0 1.5e-36 125.7 0.0 2.4 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 OAP64389.1 - 0.00026 20.0 0.0 0.00058 18.9 0.0 1.5 2 0 0 2 2 2 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 OAP64389.1 - 0.016 14.2 0.0 0.027 13.5 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Hydrolase_4 PF12146.8 OAP64389.1 - 0.035 13.4 0.1 0.1 11.8 0.0 1.8 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Ras PF00071.22 OAP64390.1 - 8.1e-49 165.3 0.0 9.8e-49 165.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAP64390.1 - 5e-29 101.0 0.0 1.3e-28 99.6 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAP64390.1 - 8e-10 38.4 0.0 1.1e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.22 OAP64390.1 - 0.00061 20.2 0.1 0.0035 17.7 0.1 2.0 1 1 0 1 1 1 1 RNA helicase MMR_HSR1 PF01926.23 OAP64390.1 - 0.0012 18.9 0.0 0.0021 18.1 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OAP64390.1 - 0.0052 16.2 0.0 0.0068 15.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 OAP64390.1 - 0.019 14.1 1.3 1.2 8.2 0.1 2.4 2 1 1 3 3 3 0 G-protein alpha subunit Pox_A32 PF04665.12 OAP64390.1 - 0.021 14.3 0.1 0.04 13.4 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein RsgA_GTPase PF03193.16 OAP64390.1 - 0.022 14.7 0.1 6 6.8 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_7 PF12775.7 OAP64390.1 - 0.036 13.6 0.0 0.062 12.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 OAP64390.1 - 0.065 12.9 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 OAP64390.1 - 0.068 13.2 0.1 0.14 12.1 0.1 1.6 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 OAP64390.1 - 0.11 12.6 0.2 0.22 11.7 0.2 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 OAP64390.1 - 0.12 12.7 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Septin PF00735.18 OAP64390.1 - 0.22 10.8 0.7 0.31 10.3 0.1 1.5 2 0 0 2 2 2 0 Septin Nas2_N PF18265.1 OAP64391.1 - 1.7e-29 101.5 0.1 2.4e-29 101.0 0.1 1.2 1 0 0 1 1 1 1 Nas2 N_terminal domain PDZ_6 PF17820.1 OAP64391.1 - 7.7e-06 25.7 0.0 1.4e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 OAP64391.1 - 1.1e-05 25.7 0.0 2.3e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.14 OAP64391.1 - 7.8e-05 23.0 0.0 0.00015 22.1 0.0 1.5 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain PDZ PF00595.24 OAP64391.1 - 0.00074 19.8 0.0 0.0014 18.9 0.0 1.5 1 0 0 1 1 1 1 PDZ domain RhoGEF PF00621.20 OAP64392.1 - 1.7e-27 96.9 0.0 3e-27 96.0 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain FAD_binding_8 PF08022.12 OAP64395.1 - 2.8e-22 78.9 0.0 5.7e-22 77.9 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 OAP64395.1 - 1.2e-21 77.5 0.0 2.1e-21 76.7 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 OAP64395.1 - 3.1e-20 72.5 9.6 3.1e-20 72.5 9.6 2.3 1 1 1 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.24 OAP64395.1 - 0.05 14.0 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 OAP64395.1 - 0.16 12.6 0.0 3.2 8.4 0.0 2.4 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain SBDS PF01172.18 OAP64396.1 - 1.9e-25 88.7 0.2 2.2e-25 88.5 0.2 1.0 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein Mannosyl_trans3 PF11051.8 OAP64397.1 - 1.5e-31 109.8 0.0 2.4e-31 109.1 0.0 1.4 1 0 0 1 1 1 1 Mannosyltransferase putative p450 PF00067.22 OAP64398.1 - 1.1e-80 271.6 0.0 1.3e-80 271.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 NIF PF03031.18 OAP64399.1 - 1.8e-53 180.5 0.1 2.6e-53 180.0 0.1 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Abhydrolase_1 PF00561.20 OAP64400.1 - 2.6e-23 83.0 0.0 2.2e-19 70.1 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAP64400.1 - 1.3e-16 60.6 0.0 2.7e-15 56.3 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OAP64400.1 - 3.7e-14 53.9 0.0 6.1e-14 53.2 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 OAP64400.1 - 4.6e-08 33.1 0.0 0.049 13.4 0.1 3.1 2 1 1 3 3 3 2 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 OAP64400.1 - 5.1e-05 22.9 0.0 0.0037 16.8 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family DLH PF01738.18 OAP64400.1 - 0.00011 21.9 0.0 0.44 10.1 0.0 2.1 2 0 0 2 2 2 2 Dienelactone hydrolase family BAAT_C PF08840.11 OAP64400.1 - 0.0004 20.4 0.0 0.00099 19.1 0.0 1.5 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Ndr PF03096.14 OAP64400.1 - 0.00046 19.0 0.0 0.0014 17.4 0.0 1.7 2 0 0 2 2 2 1 Ndr family DUF1749 PF08538.10 OAP64400.1 - 0.017 14.3 0.0 0.59 9.2 0.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1749) Esterase PF00756.20 OAP64400.1 - 0.044 13.4 0.3 0.075 12.7 0.1 1.5 2 0 0 2 2 2 0 Putative esterase Thioesterase PF00975.20 OAP64400.1 - 0.045 13.9 0.1 0.093 12.8 0.1 1.5 2 0 0 2 2 2 0 Thioesterase domain DUF915 PF06028.11 OAP64400.1 - 0.078 12.3 0.1 0.85 8.9 0.0 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) EMP70 PF02990.16 OAP64401.1 - 4.6e-187 622.8 0.1 5.5e-187 622.5 0.1 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 Arrestin_N PF00339.29 OAP64402.1 - 6.8e-05 23.0 0.0 0.00019 21.5 0.0 1.8 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Bul1_N PF04425.12 OAP64402.1 - 0.00029 19.8 0.0 0.00053 18.9 0.0 1.4 1 0 0 1 1 1 1 Bul1 N terminus Bul1_C PF04426.12 OAP64402.1 - 0.00045 19.7 0.1 0.00076 19.0 0.1 1.3 1 0 0 1 1 1 1 Bul1 C terminus Fungal_trans_2 PF11951.8 OAP64405.1 - 4.2e-06 25.8 0.4 4.2e-06 25.8 0.4 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain IU_nuc_hydro PF01156.19 OAP64405.1 - 0.0034 17.0 0.0 0.0059 16.2 0.0 1.3 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase DUF4191 PF13829.6 OAP64406.1 - 0.64 9.3 7.7 0.074 12.4 0.6 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4191) CHD5 PF04420.14 OAP64406.1 - 0.7 9.7 2.8 1.8 8.4 2.8 1.7 1 0 0 1 1 1 0 CHD5-like protein EBP PF05241.12 OAP64407.1 - 2.2e-55 186.8 9.3 3.7e-55 186.1 9.3 1.2 1 0 0 1 1 1 1 Emopamil binding protein Sulfotransfer_3 PF13469.6 OAP64408.1 - 0.0001 22.8 1.2 0.1 12.9 0.0 3.7 3 1 0 3 3 3 2 Sulfotransferase family Collagen PF01391.18 OAP64408.1 - 0.0003 20.5 3.6 0.0003 20.5 3.6 1.9 2 0 0 2 2 2 1 Collagen triple helix repeat (20 copies) AAA_2 PF07724.14 OAP64409.1 - 3.6e-47 160.7 0.0 9e-46 156.1 0.0 2.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 OAP64409.1 - 2.4e-33 114.1 0.4 2.4e-33 114.1 0.4 5.7 4 2 2 7 7 6 1 AAA lid domain AAA PF00004.29 OAP64409.1 - 2.3e-26 92.8 0.0 2.9e-14 53.6 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 OAP64409.1 - 1.5e-24 85.8 0.8 6.6e-24 83.8 0.8 2.2 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 OAP64409.1 - 4e-15 56.0 1.0 2.8e-09 37.1 0.0 3.8 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 OAP64409.1 - 9e-13 48.7 0.5 4.5e-05 23.7 0.0 4.8 3 1 1 4 4 3 2 AAA domain AAA_16 PF13191.6 OAP64409.1 - 7.6e-11 42.7 14.3 3.5e-06 27.5 0.0 5.9 4 3 0 5 5 5 2 AAA ATPase domain Sigma54_activat PF00158.26 OAP64409.1 - 6.3e-09 35.8 0.0 2.1e-05 24.3 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain Clp_N PF02861.20 OAP64409.1 - 2.5e-08 33.9 5.8 7.7e-05 22.7 0.3 4.2 3 0 0 3 3 3 1 Clp amino terminal domain, pathogenicity island component AAA_14 PF13173.6 OAP64409.1 - 1.4e-06 28.3 0.0 0.1 12.7 0.0 3.3 4 0 0 4 4 2 2 AAA domain AAA_7 PF12775.7 OAP64409.1 - 3.5e-06 26.6 0.0 0.017 14.6 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region IstB_IS21 PF01695.17 OAP64409.1 - 4.3e-06 26.6 0.0 0.1 12.3 0.0 2.8 2 0 0 2 2 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.21 OAP64409.1 - 1.3e-05 24.7 0.2 0.18 11.2 0.1 3.6 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 OAP64409.1 - 1.8e-05 24.9 1.6 0.27 11.4 0.0 3.9 3 1 0 3 3 3 2 AAA domain AAA_30 PF13604.6 OAP64409.1 - 3.9e-05 23.4 0.1 0.46 10.2 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_18 PF13238.6 OAP64409.1 - 4.4e-05 24.0 5.6 0.07 13.7 0.0 4.4 5 1 1 6 6 3 2 AAA domain RNA_helicase PF00910.22 OAP64409.1 - 9.5e-05 22.7 0.0 0.56 10.6 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_28 PF13521.6 OAP64409.1 - 0.00011 22.5 2.3 0.44 10.8 0.0 3.7 3 1 1 4 4 4 2 AAA domain AAA_3 PF07726.11 OAP64409.1 - 0.00018 21.4 0.0 1 9.3 0.0 3.4 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 OAP64409.1 - 0.00023 21.1 0.1 0.21 11.5 0.0 3.0 2 1 0 2 2 2 1 RsgA GTPase AAA_19 PF13245.6 OAP64409.1 - 0.0004 20.7 0.4 0.12 12.7 0.2 3.5 3 1 0 3 3 3 1 AAA domain RuvB_N PF05496.12 OAP64409.1 - 0.00047 19.9 1.2 2.6 7.7 0.7 4.3 3 1 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 OAP64409.1 - 0.00049 19.9 0.0 0.53 10.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 OAP64409.1 - 0.00055 19.9 0.0 0.65 10.0 0.0 2.6 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE T2SSE PF00437.20 OAP64409.1 - 0.00056 19.0 0.2 0.011 14.8 0.0 2.7 2 1 0 2 2 2 1 Type II/IV secretion system protein Torsin PF06309.11 OAP64409.1 - 0.001 19.1 0.0 0.0064 16.6 0.0 2.2 2 0 0 2 2 2 1 Torsin AAA_29 PF13555.6 OAP64409.1 - 0.0013 18.4 0.0 1.3 8.8 0.0 2.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain ABC_tran PF00005.27 OAP64409.1 - 0.0016 19.0 4.5 1 9.9 0.0 3.8 4 0 0 4 4 3 1 ABC transporter ATPase_2 PF01637.18 OAP64409.1 - 0.0024 17.8 9.6 0.034 14.1 0.3 4.6 5 1 1 6 6 4 1 ATPase domain predominantly from Archaea ResIII PF04851.15 OAP64409.1 - 0.0044 17.1 0.0 2 8.4 0.0 3.7 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Zeta_toxin PF06414.12 OAP64409.1 - 0.0062 15.8 0.0 2.1 7.6 0.0 2.8 2 0 0 2 2 2 1 Zeta toxin NACHT PF05729.12 OAP64409.1 - 0.0071 16.3 0.0 0.9 9.4 0.0 3.1 3 0 0 3 3 2 1 NACHT domain Roc PF08477.13 OAP64409.1 - 0.0072 16.5 0.0 2.3 8.4 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase SRP54 PF00448.22 OAP64409.1 - 0.011 15.4 0.0 1.8 8.1 0.0 2.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain NTPase_1 PF03266.15 OAP64409.1 - 0.022 14.6 0.0 0.49 10.3 0.0 2.8 2 0 0 2 2 2 0 NTPase Rad17 PF03215.15 OAP64409.1 - 0.041 13.8 0.0 9.4 6.1 0.0 2.6 2 0 0 2 2 2 0 Rad17 P-loop domain PduV-EutP PF10662.9 OAP64409.1 - 0.076 12.8 0.0 7.5 6.3 0.0 2.9 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_21 PF13304.6 OAP64409.1 - 0.081 12.7 1.2 21 4.8 0.0 3.7 4 0 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system Snapin_Pallidin PF14712.6 OAP64409.1 - 0.19 12.2 17.0 0.77 10.2 3.2 3.9 3 1 1 4 4 3 0 Snapin/Pallidin AAA_23 PF13476.6 OAP64409.1 - 0.38 11.2 0.0 0.38 11.2 0.0 5.4 5 2 1 6 6 2 0 AAA domain TMF_TATA_bd PF12325.8 OAP64409.1 - 0.92 9.8 18.3 0.19 11.9 12.7 2.8 2 1 1 3 3 2 0 TATA element modulatory factor 1 TATA binding V_ATPase_I PF01496.19 OAP64409.1 - 1.3 6.8 8.1 0.13 10.2 2.5 1.9 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family AAA_25 PF13481.6 OAP64409.1 - 1.4 8.5 5.0 16 5.0 0.0 3.4 3 1 0 3 3 3 0 AAA domain T2SSF PF00482.23 OAP64409.1 - 1.5 8.8 6.0 6.6 6.7 1.3 3.5 4 0 0 4 4 2 0 Type II secretion system (T2SS), protein F Phage_GP20 PF06810.11 OAP64409.1 - 5.8 6.7 21.1 0.053 13.3 3.1 3.3 2 1 1 3 3 3 0 Phage minor structural protein GP20 CENP-X PF09415.10 OAP64410.1 - 2.5e-21 75.7 2.2 3.8e-21 75.2 0.0 2.3 2 1 0 2 2 1 1 CENP-S associating Centromere protein X Nop14 PF04147.12 OAP64410.1 - 0.0023 16.3 14.4 0.0027 16.0 14.4 1.1 1 0 0 1 1 1 1 Nop14-like family CBFD_NFYB_HMF PF00808.23 OAP64410.1 - 0.0036 17.6 0.0 0.007 16.6 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone BUD22 PF09073.10 OAP64410.1 - 0.0065 15.9 16.7 0.0087 15.5 16.7 1.1 1 0 0 1 1 1 1 BUD22 CNDH2_C PF16858.5 OAP64410.1 - 0.025 14.5 3.0 0.029 14.2 3.0 1.3 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Nop25 PF09805.9 OAP64410.1 - 0.2 12.1 11.0 0.31 11.5 11.0 1.3 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) DUF5523 PF17661.1 OAP64410.1 - 0.38 10.4 9.6 0.56 9.8 9.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5523) RRN3 PF05327.11 OAP64410.1 - 0.44 9.0 10.5 0.52 8.8 10.5 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 TFIIA PF03153.13 OAP64410.1 - 1.3 8.9 19.2 2 8.4 19.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 OAP64410.1 - 1.8 7.2 3.7 2 7.1 3.7 1.2 1 0 0 1 1 1 0 Presenilin DUF913 PF06025.12 OAP64410.1 - 2 7.3 4.3 10 5.0 5.1 1.8 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Roughex PF06020.11 OAP64410.1 - 8 5.5 15.8 1.9 7.5 12.6 1.6 2 0 0 2 2 2 0 Drosophila roughex protein Ecl1 PF12855.7 OAP64411.1 - 8.9 7.4 29.3 15 6.7 16.1 2.3 2 0 0 2 2 2 0 ECL1/2/3 zinc binding proteins Cu_bind_like PF02298.17 OAP64412.1 - 0.075 13.1 0.0 0.21 11.6 0.0 1.7 1 1 0 1 1 1 0 Plastocyanin-like domain Zn_ribbon_recom PF13408.6 OAP64413.1 - 0.021 15.3 0.3 0.07 13.7 0.5 1.7 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain RecX PF02631.16 OAP64413.1 - 0.16 12.4 0.2 0.31 11.5 0.2 1.5 1 1 0 1 1 1 0 RecX family AT_hook PF02178.19 OAP64413.1 - 2 8.6 10.6 5.6 7.2 10.6 1.8 1 0 0 1 1 1 0 AT hook motif Mis12 PF05859.12 OAP64414.1 - 2.9e-45 153.6 0.0 5.5e-45 152.7 0.0 1.5 1 0 0 1 1 1 1 Mis12 protein T6SS_VipA PF05591.12 OAP64414.1 - 0.14 11.9 1.5 5 6.9 0.2 2.3 2 0 0 2 2 2 0 Type VI secretion system, VipA, VC_A0107 or Hcp2 ZapB PF06005.12 OAP64414.1 - 0.24 11.9 5.5 11 6.6 0.1 3.1 3 0 0 3 3 3 0 Cell division protein ZapB CD20 PF04103.15 OAP64415.1 - 0.37 10.9 6.3 0.68 10.0 4.8 2.3 1 1 1 2 2 2 0 CD20-like family DUF202 PF02656.15 OAP64415.1 - 8.3 6.9 8.6 12 6.5 6.1 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF202) Glyco_hydro_43 PF04616.14 OAP64416.1 - 3.8e-18 65.8 0.0 5.1e-18 65.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Cu-oxidase_3 PF07732.15 OAP64417.1 - 7.1e-35 119.6 2.4 3.8e-34 117.3 0.4 2.9 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 OAP64417.1 - 1.5e-27 96.0 3.5 5.8e-22 77.9 0.1 3.3 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 OAP64417.1 - 1.6e-13 51.1 0.4 6.8e-11 42.5 0.0 3.4 3 1 0 3 3 3 2 Multicopper oxidase Aldedh PF00171.22 OAP64419.1 - 2.9e-142 474.5 0.0 3.2e-142 474.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family AAA_25 PF13481.6 OAP64419.1 - 0.024 14.2 0.1 0.056 13.0 0.1 1.6 1 0 0 1 1 1 0 AAA domain UDG PF03167.19 OAP64420.1 - 1.3e-18 67.5 0.0 2.3e-18 66.7 0.0 1.4 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily XRCC4 PF06632.12 OAP64420.1 - 4.4 6.1 6.7 6.5 5.5 6.7 1.2 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Het-C PF07217.11 OAP64421.1 - 3.3e-244 811.6 0.0 4.3e-244 811.2 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C DUF1722 PF08349.11 OAP64421.1 - 0.064 13.5 0.0 0.17 12.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1722) DUF2547 PF10818.8 OAP64421.1 - 1.7 9.6 4.4 4.5 8.3 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2547) Ank_2 PF12796.7 OAP64422.1 - 9.5e-18 64.6 21.8 2.4e-08 34.4 0.1 8.2 8 2 1 9 9 9 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAP64422.1 - 7e-11 42.4 2.5 0.19 12.4 0.0 7.8 6 1 2 8 8 8 4 Ankyrin repeats (many copies) IBR PF01485.21 OAP64422.1 - 2.4e-06 27.6 21.9 0.0016 18.6 2.9 4.1 4 0 0 4 4 4 2 IBR domain, a half RING-finger domain Ank_3 PF13606.6 OAP64422.1 - 1.8e-05 24.8 10.1 18 6.3 0.0 10.0 10 0 0 10 10 10 1 Ankyrin repeat Ank_5 PF13857.6 OAP64422.1 - 0.0014 18.9 7.9 0.15 12.4 0.0 5.7 7 0 0 7 7 7 1 Ankyrin repeats (many copies) Ank PF00023.30 OAP64422.1 - 0.0054 17.1 12.7 7.3 7.2 0.0 8.6 10 0 0 10 10 10 1 Ankyrin repeat Cupin_2 PF07883.11 OAP64423.1 - 0.00013 21.6 0.6 0.00028 20.6 0.6 1.6 1 0 0 1 1 1 1 Cupin domain FA_desaturase PF00487.24 OAP64424.1 - 0.0019 18.1 4.6 0.0031 17.4 4.6 1.3 1 0 0 1 1 1 1 Fatty acid desaturase DUF1691 PF07950.11 OAP64424.1 - 0.0063 17.2 0.0 0.015 16.0 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1691) Tetraspanin PF00335.20 OAP64424.1 - 0.37 10.5 2.4 0.69 9.6 2.4 1.3 1 1 0 1 1 1 0 Tetraspanin family 4HBT_3 PF13622.6 OAP64425.1 - 3.7e-80 269.8 0.3 4.6e-80 269.4 0.3 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 OAP64425.1 - 7.5e-24 84.1 0.0 5.3e-11 42.5 0.0 4.3 3 1 0 3 3 3 3 Acyl-CoA thioesterase Prefoldin_2 PF01920.20 OAP64426.1 - 2.7e-17 62.6 0.4 3.3e-17 62.4 0.4 1.1 1 0 0 1 1 1 1 Prefoldin subunit End3 PF12761.7 OAP64426.1 - 0.0017 18.6 0.1 0.026 14.7 0.0 2.0 2 0 0 2 2 2 1 Actin cytoskeleton-regulatory complex protein END3 MAD PF05557.13 OAP64426.1 - 0.014 13.8 0.2 0.017 13.5 0.2 1.0 1 0 0 1 1 1 0 Mitotic checkpoint protein Prefoldin PF02996.17 OAP64426.1 - 0.023 14.6 2.9 0.03 14.2 0.4 1.9 1 1 1 2 2 2 0 Prefoldin subunit bZIP_1 PF00170.21 OAP64426.1 - 0.072 13.2 1.9 0.089 12.9 0.3 1.8 2 0 0 2 2 2 0 bZIP transcription factor Lzipper-MIP1 PF14389.6 OAP64426.1 - 0.084 13.2 3.3 1.4 9.3 0.1 2.3 2 1 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Type2_restr_D3 PF16902.5 OAP64426.1 - 0.11 12.4 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Type-2 restriction enzyme D3 domain Rx_N PF18052.1 OAP64426.1 - 0.17 12.2 1.9 5.6 7.3 0.2 2.2 2 0 0 2 2 2 0 Rx N-terminal domain FlaC_arch PF05377.11 OAP64426.1 - 0.18 12.2 0.5 0.85 10.1 0.0 2.0 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF2452 PF10504.9 OAP64426.1 - 0.19 11.2 0.5 6.8 6.1 0.1 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF2452) MerR-DNA-bind PF09278.11 OAP64426.1 - 0.61 10.7 5.6 14 6.3 2.1 3.0 3 1 0 3 3 3 0 MerR, DNA binding Spc7 PF08317.11 OAP64426.1 - 1.5 7.6 5.6 10 4.9 5.5 1.8 1 1 1 2 2 2 0 Spc7 kinetochore protein Isochorismatase PF00857.20 OAP64427.1 - 6.7e-15 55.7 0.0 1.1e-14 55.0 0.0 1.3 1 1 0 1 1 1 1 Isochorismatase family ATG27 PF09451.10 OAP64428.1 - 2.1e-98 329.4 0.0 2.5e-98 329.2 0.0 1.0 1 0 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.18 OAP64428.1 - 0.003 17.7 0.1 0.25 11.4 0.0 2.5 3 0 0 3 3 3 1 Cation-independent mannose-6-phosphate receptor repeat FAM176 PF14851.6 OAP64428.1 - 0.45 10.2 3.9 0.22 11.2 1.7 1.6 2 0 0 2 2 2 0 FAM176 family Peptidase_S49_N PF08496.10 OAP64428.1 - 0.52 10.4 1.8 0.85 9.7 1.8 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Asp-B-Hydro_N PF05279.11 OAP64428.1 - 0.78 9.8 7.1 0.15 12.1 0.7 2.2 2 0 0 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region CHAT PF12770.7 OAP64430.1 - 4.5e-25 88.7 0.5 2.1e-24 86.5 0.4 2.0 2 0 0 2 2 2 1 CHAT domain Peptidase_C50 PF03568.17 OAP64430.1 - 0.12 11.4 0.0 0.28 10.3 0.0 1.5 1 0 0 1 1 1 0 Peptidase family C50 TPR_2 PF07719.17 OAP64430.1 - 0.19 12.0 4.1 18 5.7 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Fib_alpha PF08702.10 OAP64430.1 - 0.28 11.4 2.2 8.9 6.5 0.1 3.2 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family TPR_12 PF13424.6 OAP64430.1 - 3.5 8.0 12.9 17 5.8 0.1 6.3 7 2 2 9 9 9 0 Tetratricopeptide repeat Alpha-amylase PF00128.24 OAP64431.1 - 3.3e-58 197.8 0.7 4.7e-56 190.8 0.7 2.1 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 OAP64431.1 - 2.3e-05 24.4 0.0 4.9e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain Acetyltransf_7 PF13508.7 OAP64432.1 - 2.9e-07 30.8 0.0 1e-06 29.0 0.0 2.0 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAP64432.1 - 1.2e-06 28.8 0.0 2.2e-06 27.9 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OAP64432.1 - 2.7e-05 24.1 0.1 7e-05 22.8 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 OAP64432.1 - 0.00043 20.3 0.0 0.00082 19.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAP64432.1 - 0.0047 16.9 0.0 0.011 15.7 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.6 OAP64432.1 - 0.0059 16.3 0.0 0.0094 15.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Rhomboid PF01694.22 OAP64433.1 - 5.4e-11 42.7 10.6 7.5e-11 42.2 10.6 1.1 1 0 0 1 1 1 1 Rhomboid family Fungal_trans_2 PF11951.8 OAP64434.1 - 1.4e-05 24.1 1.3 0.00019 20.4 0.1 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Herpes_BLRF2 PF05812.12 OAP64434.1 - 0.019 15.1 0.0 0.043 14.0 0.0 1.6 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein GMC_oxred_N PF00732.19 OAP64435.1 - 4e-55 187.3 0.0 5.3e-55 186.9 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAP64435.1 - 4.8e-32 111.5 0.1 7e-32 110.9 0.1 1.2 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 OAP64435.1 - 4.6e-05 23.6 0.1 0.00017 21.8 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 OAP64435.1 - 0.00055 19.1 0.1 0.0015 17.7 0.1 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.24 OAP64435.1 - 0.00084 19.0 2.7 0.0029 17.2 1.4 2.5 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAP64435.1 - 0.0058 15.9 0.0 0.16 11.2 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAP64435.1 - 0.046 12.8 0.4 2.4 7.2 0.1 2.2 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_3 PF13738.6 OAP64435.1 - 0.08 12.2 0.1 4.6 6.4 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.15 OAP64435.1 - 0.19 10.3 0.0 0.27 9.7 0.0 1.2 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) MFS_1 PF07690.16 OAP64436.1 - 1e-25 90.4 26.5 1.5e-25 89.9 26.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Thaumatin PF00314.17 OAP64438.1 - 2.9e-66 223.2 4.8 4e-66 222.7 4.8 1.2 1 0 0 1 1 1 1 Thaumatin family Glyco_hydro_64 PF16483.5 OAP64438.1 - 0.038 13.3 0.2 0.61 9.3 0.0 2.1 2 0 0 2 2 2 0 Beta-1,3-glucanase MadM PF03818.13 OAP64438.1 - 0.074 12.9 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Malonate/sodium symporter MadM subunit DUF3455 PF11937.8 OAP64440.1 - 8.9e-42 143.2 0.1 1.4e-41 142.5 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) DUF2990 PF11693.8 OAP64440.1 - 1.5e-11 44.3 0.3 4.5e-11 42.7 0.3 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF2990) CASP_C PF08172.12 OAP64441.1 - 6e-89 297.7 0.1 6e-89 297.7 0.1 4.1 3 1 1 4 4 4 1 CASP C terminal DUF4472 PF14739.6 OAP64441.1 - 0.034 14.9 2.2 0.034 14.9 2.2 6.1 5 1 2 7 7 7 0 Domain of unknown function (DUF4472) HALZ PF02183.18 OAP64441.1 - 0.33 11.2 0.1 0.33 11.2 0.1 8.3 9 1 1 10 10 10 0 Homeobox associated leucine zipper bZIP_2 PF07716.15 OAP64441.1 - 0.35 11.0 0.1 0.046 13.8 3.7 7.8 7 2 0 7 7 7 0 Basic region leucine zipper APG6_N PF17675.1 OAP64441.1 - 1.9 9.0 74.3 1.3 9.6 8.9 6.0 2 1 4 6 6 6 0 Apg6 coiled-coil region NAD_binding_1 PF00175.21 OAP64441.1 - 4.2 8.1 5.4 12 6.6 0.0 3.5 3 1 0 3 3 3 0 Oxidoreductase NAD-binding domain Vps39_2 PF10367.9 OAP64442.1 - 1.2e-06 28.9 0.0 3.1e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.9 OAP64442.1 - 0.025 14.8 0.1 0.87 9.9 0.1 2.6 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 Ras PF00071.22 OAP64443.1 - 1.1e-42 145.4 0.0 1.9e-37 128.4 0.0 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 OAP64443.1 - 8.5e-30 103.4 0.0 2.4e-29 102.0 0.0 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAP64443.1 - 3.6e-11 42.8 0.0 6.9e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OAP64443.1 - 1.7e-05 24.4 0.0 5.9e-05 22.7 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OAP64443.1 - 0.00035 20.6 0.0 0.00055 20.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_30 PF13604.6 OAP64443.1 - 0.0011 18.7 0.9 0.0018 18.0 0.1 1.7 2 0 0 2 2 2 1 AAA domain Gtr1_RagA PF04670.12 OAP64443.1 - 0.0011 18.3 0.0 0.0015 17.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_33 PF13671.6 OAP64443.1 - 0.0043 17.2 0.0 0.0091 16.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain SRPRB PF09439.10 OAP64443.1 - 0.0076 15.7 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 OAP64443.1 - 0.0081 16.1 0.1 0.15 12.0 0.1 2.3 1 1 1 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 OAP64443.1 - 0.016 15.6 0.1 0.1 13.0 0.1 2.1 2 1 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 OAP64443.1 - 0.036 14.3 0.0 0.075 13.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 OAP64443.1 - 0.036 14.3 0.0 0.081 13.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 OAP64443.1 - 0.047 14.2 0.0 0.11 13.1 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_7 PF12775.7 OAP64443.1 - 0.067 12.7 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 OAP64443.1 - 0.074 13.0 0.1 0.4 10.6 0.0 2.0 2 0 0 2 2 2 0 NACHT domain PduV-EutP PF10662.9 OAP64443.1 - 0.093 12.5 0.0 0.79 9.5 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA PF00004.29 OAP64443.1 - 0.097 13.1 0.0 0.36 11.3 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MFS_1 PF07690.16 OAP64445.1 - 1.4e-36 126.2 31.8 1.4e-36 126.2 31.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PTR2 PF00854.21 OAP64445.1 - 0.00029 19.8 0.7 0.00029 19.8 0.7 1.7 2 0 0 2 2 2 1 POT family BT1 PF03092.16 OAP64445.1 - 0.00071 17.9 1.0 0.024 12.9 0.1 2.4 1 1 1 2 2 2 2 BT1 family Phage_Gp23 PF10669.9 OAP64445.1 - 0.098 13.0 3.2 0.51 10.7 0.2 2.4 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) Fungal_trans PF04082.18 OAP64447.1 - 4e-10 39.2 2.9 4.5e-10 39.0 2.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF2278 PF10042.9 OAP64450.1 - 3.6e-67 226.3 0.0 4.2e-67 226.1 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2278) Lipoxygenase PF00305.19 OAP64451.1 - 9.5e-45 153.2 6.2 5.4e-43 147.4 4.5 2.1 2 0 0 2 2 2 2 Lipoxygenase adh_short_C2 PF13561.6 OAP64452.1 - 1.2e-55 188.6 0.2 1.5e-55 188.3 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP64452.1 - 1.9e-52 177.6 0.3 3.4e-52 176.7 0.3 1.4 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 OAP64452.1 - 4.1e-12 46.4 0.5 8.4e-12 45.4 0.2 1.6 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 OAP64452.1 - 1.5e-05 24.6 0.1 2.1e-05 24.1 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Oxidored_nitro PF00148.19 OAP64452.1 - 0.00074 18.3 0.1 0.0014 17.5 0.1 1.4 1 0 0 1 1 1 1 Nitrogenase component 1 type Oxidoreductase Glyco_transf_5 PF08323.11 OAP64452.1 - 0.0021 17.8 0.0 0.027 14.2 0.0 2.3 2 1 1 3 3 3 1 Starch synthase catalytic domain THF_DHG_CYH_C PF02882.19 OAP64452.1 - 0.0023 17.3 0.2 0.0043 16.4 0.1 1.5 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NmrA PF05368.13 OAP64452.1 - 0.0035 16.9 0.6 0.012 15.1 0.3 1.8 2 0 0 2 2 2 1 NmrA-like family GDP_Man_Dehyd PF16363.5 OAP64452.1 - 0.0089 15.5 0.1 0.016 14.6 0.1 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Glyco_transf_4 PF13439.6 OAP64452.1 - 0.012 15.6 0.0 0.44 10.5 0.0 2.5 3 0 0 3 3 3 0 Glycosyltransferase Family 4 ADH_zinc_N PF00107.26 OAP64452.1 - 0.014 15.4 0.2 0.027 14.4 0.2 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase ACT_7 PF13840.6 OAP64452.1 - 0.061 13.1 0.5 0.92 9.3 0.0 2.5 2 0 0 2 2 2 0 ACT domain ApbA PF02558.16 OAP64452.1 - 0.1 12.2 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Ferric_reduct PF01794.19 OAP64453.1 - 6.3e-20 71.5 9.9 6.3e-20 71.5 9.9 1.9 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 OAP64453.1 - 4.2e-15 56.2 0.1 6.1e-13 49.2 0.1 2.3 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 OAP64453.1 - 1.6e-09 37.8 0.0 8.8e-06 25.8 0.0 2.9 3 0 0 3 3 3 2 FAD-binding domain NAD_binding_1 PF00175.21 OAP64453.1 - 0.012 16.3 0.0 0.024 15.3 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase NAD-binding domain GAT PF03127.14 OAP64454.1 - 6.1e-16 58.5 0.7 1.3e-15 57.4 0.7 1.6 1 0 0 1 1 1 1 GAT domain VHS PF00790.19 OAP64454.1 - 0.21 11.4 0.0 1.6 8.6 0.0 2.0 2 0 0 2 2 2 0 VHS domain His_Phos_2 PF00328.22 OAP64455.1 - 7.9e-17 61.7 0.0 5.1e-11 42.5 0.0 2.1 1 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) Gmad1 PF10647.9 OAP64456.1 - 0.11 12.3 0.0 1.7 8.4 0.0 2.2 2 0 0 2 2 2 0 Lipoprotein LpqB beta-propeller domain NmrA PF05368.13 OAP64457.1 - 1.1e-25 90.5 0.0 1.7e-25 89.9 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAP64457.1 - 2.7e-05 24.1 0.5 5.1e-05 23.2 0.0 1.7 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 OAP64457.1 - 0.0014 18.1 0.0 0.0027 17.2 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 OAP64457.1 - 0.025 15.0 0.1 0.048 14.1 0.1 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain UBA_4 PF14555.6 OAP64458.1 - 2.5e-08 33.6 3.4 2.7e-05 23.9 0.0 2.5 2 0 0 2 2 2 2 UBA-like domain UBA_4 PF14555.6 OAP64459.1 - 1.7e-07 30.9 8.2 0.025 14.4 0.7 4.0 3 1 0 3 3 3 3 UBA-like domain TAP_C PF03943.13 OAP64459.1 - 0.0019 17.8 1.6 2.2 8.0 0.0 3.4 3 0 0 3 3 3 2 TAP C-terminal domain Dus PF01207.17 OAP64460.1 - 1.3e-59 201.9 0.0 1.7e-59 201.4 0.0 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Imm39 PF15568.6 OAP64460.1 - 0.14 12.3 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 Immunity protein 39 MJ1316 PF04457.12 OAP64461.1 - 1.4e-24 86.6 0.9 1.4e-24 86.6 0.9 2.0 2 1 0 2 2 2 1 MJ1316 RNA cyclic group end recognition domain Clr5 PF14420.6 OAP64462.1 - 5.9e-20 71.2 0.1 2e-19 69.5 0.1 2.0 1 0 0 1 1 1 1 Clr5 domain Abhydrolase_6 PF12697.7 OAP64462.1 - 1.5e-08 35.5 0.2 1.5e-08 35.5 0.2 2.8 3 0 0 3 3 3 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAP64462.1 - 5.9e-06 25.7 0.1 2.7e-05 23.6 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OAP64462.1 - 0.0017 18.0 0.0 0.005 16.5 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Ndr PF03096.14 OAP64462.1 - 0.051 12.3 0.0 0.095 11.4 0.0 1.3 1 0 0 1 1 1 0 Ndr family Nucleolin_bd PF16725.5 OAP64462.1 - 0.053 13.2 0.2 0.16 11.7 0.2 1.8 1 0 0 1 1 1 0 Nucleolin binding domain Aldedh PF00171.22 OAP64463.1 - 2.8e-144 481.1 0.1 3.5e-144 480.8 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 OAP64463.1 - 5.2e-05 22.5 0.0 0.00015 21.0 0.0 1.8 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) Spt20 PF12090.8 OAP64464.1 - 0.28 10.8 8.2 0.27 10.8 8.2 1.1 1 0 0 1 1 1 0 Spt20 family RR_TM4-6 PF06459.12 OAP64464.1 - 1.7 8.4 8.3 1.8 8.3 8.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF3391 PF11871.8 OAP64464.1 - 3.5 8.2 9.7 3.5 8.2 9.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3391) Presenilin PF01080.17 OAP64464.1 - 7.1 5.3 6.4 6.8 5.3 6.4 1.0 1 0 0 1 1 1 0 Presenilin Dehydratase_hem PF13816.6 OAP64465.1 - 7.8e-81 271.8 0.0 9.3e-81 271.6 0.0 1.0 1 0 0 1 1 1 1 Haem-containing dehydratase CN_hydrolase PF00795.22 OAP64466.1 - 6.8e-48 163.3 0.0 8.1e-48 163.0 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Sdh_cyt PF01127.22 OAP64467.1 - 1.6e-19 70.1 4.7 2e-19 69.8 4.7 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit APH PF01636.23 OAP64468.1 - 0.024 14.6 0.4 0.064 13.2 0.4 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family DIOX_N PF14226.6 OAP64469.1 - 6.3e-35 120.5 0.0 2.9e-33 115.1 0.0 2.3 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OAP64469.1 - 1.1e-14 54.7 0.0 2e-14 53.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily GxGYxYP_C PF14323.6 OAP64469.1 - 0.16 11.9 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 GxGYxYP putative glycoside hydrolase C-terminal domain FAD-oxidase_C PF02913.19 OAP64470.1 - 7.1e-61 206.0 0.2 1e-60 205.4 0.2 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 OAP64470.1 - 1.4e-38 131.7 0.0 2.6e-38 130.9 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain ADH_N PF08240.12 OAP64471.1 - 1.4e-33 115.0 2.0 1.9e-33 114.6 0.1 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAP64471.1 - 3.2e-24 85.3 0.3 5.9e-24 84.5 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 OAP64471.1 - 4e-08 33.0 0.4 6.6e-08 32.3 0.4 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 OAP64471.1 - 3.8e-07 29.6 1.2 7.1e-07 28.7 1.2 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.6 OAP64471.1 - 3.1e-05 25.0 0.1 6.4e-05 24.0 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.14 OAP64471.1 - 0.00058 19.5 0.0 0.0009 18.9 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox_2 PF07992.14 OAP64471.1 - 0.0098 15.2 0.3 0.019 14.2 0.2 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_25 PF13649.6 OAP64471.1 - 0.01 16.5 0.1 0.02 15.6 0.1 1.6 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 OAP64471.1 - 0.025 14.0 0.3 0.038 13.4 0.3 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Met_10 PF02475.16 OAP64471.1 - 0.032 14.0 0.1 0.065 13.0 0.1 1.4 1 0 0 1 1 1 0 Met-10+ like-protein MTS PF05175.14 OAP64471.1 - 0.038 13.5 0.1 0.065 12.8 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_11 PF08241.12 OAP64471.1 - 0.046 14.4 0.0 0.098 13.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain 2-Hacid_dh_C PF02826.19 OAP64471.1 - 0.088 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 OAP64471.1 - 0.16 11.2 0.0 0.27 10.4 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SGL PF08450.12 OAP64472.1 - 2.6e-21 76.3 0.3 2.6e-20 73.1 0.3 2.0 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 OAP64472.1 - 1.3e-05 25.3 0.0 9.8e-05 22.4 0.0 2.4 2 1 0 2 2 2 1 Strictosidine synthase PD40 PF07676.12 OAP64472.1 - 0.028 14.4 2.4 0.039 13.9 0.1 2.5 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Yae1_N PF09811.9 OAP64473.1 - 5.9e-07 29.1 2.5 1.3e-06 28.0 2.5 1.6 1 0 0 1 1 1 1 Essential protein Yae1, N terminal tRNA-synt_1g PF09334.11 OAP64474.1 - 1.3e-149 498.2 0.0 1.8e-149 497.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 OAP64474.1 - 1.3e-07 30.3 0.1 4.1e-05 22.0 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) DZR PF12773.7 OAP64474.1 - 0.99 9.5 4.5 2.6 8.1 4.2 1.7 1 1 1 2 2 2 0 Double zinc ribbon Ribosomal_L6e PF01159.19 OAP64474.1 - 1.4 9.5 6.1 3.5 8.2 6.1 1.6 1 0 0 1 1 1 0 Ribosomal protein L6e zf-ribbon_3 PF13248.6 OAP64474.1 - 2.3 7.8 7.8 4.9 6.7 0.6 2.5 2 0 0 2 2 2 0 zinc-ribbon domain Zn_clus PF00172.18 OAP64476.1 - 0.00083 19.4 0.8 0.0015 18.6 0.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CENP-R PF06729.12 OAP64476.1 - 0.84 9.6 4.1 0.8 9.6 1.0 2.2 2 0 0 2 2 2 0 Kinetochore component, CENP-R TauD PF02668.16 OAP64477.1 - 1.9e-16 60.7 0.0 2.8e-16 60.1 0.0 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CTP_transf_like PF01467.26 OAP64478.1 - 5.7e-08 33.1 0.1 2.3e-05 24.6 0.1 2.3 2 0 0 2 2 2 2 Cytidylyltransferase-like Cyclin_C_2 PF16899.5 OAP64479.1 - 5e-29 100.8 0.1 4e-24 85.0 0.0 2.5 2 0 0 2 2 2 2 Cyclin C-terminal domain Cyclin_N PF00134.23 OAP64479.1 - 2.2e-07 30.6 0.0 4.1e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain GlutR_dimer PF00745.20 OAP64479.1 - 0.019 15.4 1.0 0.84 10.1 0.1 2.6 2 0 0 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain WD40 PF00400.32 OAP64481.1 - 9.2e-16 58.0 4.7 0.0032 18.3 0.0 5.6 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAP64481.1 - 2.1e-06 27.9 0.0 0.0045 17.3 0.0 4.2 1 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OAP64481.1 - 0.0069 15.4 0.2 0.23 10.4 0.0 2.6 2 1 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 OAP64481.1 - 0.015 14.0 0.4 0.11 11.1 0.1 2.2 2 1 1 3 3 3 0 Nucleoporin Nup120/160 WD40_like PF17005.5 OAP64481.1 - 0.05 12.9 0.0 0.085 12.2 0.0 1.3 1 0 0 1 1 1 0 WD40-like domain Kelch_4 PF13418.6 OAP64482.1 - 2.6e-23 81.8 3.8 1.9e-05 24.5 0.0 4.8 4 0 0 4 4 4 4 Galactose oxidase, central domain Kelch_5 PF13854.6 OAP64482.1 - 3.9e-22 77.8 0.4 1.5e-05 24.9 0.0 4.5 4 0 0 4 4 4 4 Kelch motif Kelch_6 PF13964.6 OAP64482.1 - 4.2e-22 77.6 2.0 8.8e-06 25.8 0.1 4.8 2 1 2 4 4 4 4 Kelch motif Kelch_2 PF07646.15 OAP64482.1 - 6.9e-19 67.0 1.9 1.6e-05 24.7 0.0 4.6 4 0 0 4 4 4 3 Kelch motif Kelch_1 PF01344.25 OAP64482.1 - 5.2e-17 61.2 0.3 1.9e-06 27.3 0.0 4.4 4 0 0 4 4 4 3 Kelch motif Kelch_3 PF13415.6 OAP64482.1 - 3.1e-15 56.0 6.7 5.9e-07 29.6 0.1 5.5 5 1 1 6 6 6 3 Galactose oxidase, central domain BTB PF00651.31 OAP64482.1 - 1.7e-10 41.1 0.1 3.2e-10 40.2 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 OAP64482.1 - 0.0049 16.9 0.0 0.012 15.7 0.0 1.6 1 0 0 1 1 1 1 BTB And C-terminal Kelch ANAPC4_WD40 PF12894.7 OAP64483.1 - 1.4e-16 60.6 7.0 5.8e-06 26.5 0.2 4.4 3 1 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OAP64483.1 - 2.3e-15 56.7 19.4 0.00033 21.4 0.1 6.6 7 0 0 7 7 7 5 WD domain, G-beta repeat Ge1_WD40 PF16529.5 OAP64483.1 - 5.3e-06 25.6 0.1 0.00056 19.0 0.0 3.2 1 1 2 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 OAP64483.1 - 0.00015 21.7 0.2 0.019 14.8 0.1 2.5 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A CK2S PF15011.6 OAP64484.1 - 0.071 13.0 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 Casein Kinase 2 substrate Fer4_13 PF13370.6 OAP64484.1 - 0.5 11.0 1.8 2.2 8.9 0.0 2.9 3 1 0 3 3 3 0 4Fe-4S single cluster domain of Ferredoxin I FliJ PF02050.16 OAP64485.1 - 0.019 15.2 0.3 4.3 7.6 0.0 2.4 2 0 0 2 2 2 0 Flagellar FliJ protein zf-CCHC PF00098.23 OAP64486.1 - 1.2e-23 82.0 22.9 3.3e-09 36.4 2.4 3.2 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC_5 PF14787.6 OAP64486.1 - 6.4e-11 41.8 10.4 0.00046 19.8 0.0 3.3 1 1 2 3 3 3 3 GAG-polyprotein viral zinc-finger zf-CCHC_3 PF13917.6 OAP64486.1 - 5.7e-06 26.2 13.2 0.0075 16.2 0.5 3.1 2 1 1 3 3 3 3 Zinc knuckle zf-CCHC_4 PF14392.6 OAP64486.1 - 0.0011 18.6 12.3 0.22 11.3 0.7 3.1 3 0 0 3 3 3 3 Zinc knuckle HscB_4_cys PF18256.1 OAP64486.1 - 0.14 12.0 6.7 8.8 6.2 0.1 3.5 3 0 0 3 3 3 0 Co-chaperone HscB tetracysteine metal binding motif zf-ribbon_3 PF13248.6 OAP64486.1 - 6 6.4 15.2 7.2 6.2 0.5 3.3 3 0 0 3 3 3 0 zinc-ribbon domain UDPGP PF01704.18 OAP64487.1 - 7.2e-56 189.6 0.0 9.5e-56 189.2 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Pro_isomerase PF00160.21 OAP64488.1 - 6.3e-30 104.5 0.0 9.3e-30 104.0 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 OAP64488.1 - 4.4e-17 61.7 0.1 5.5e-16 58.1 0.1 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Vac7 PF12751.7 OAP64488.1 - 0.052 13.0 4.8 0.085 12.3 4.8 1.3 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 Nup35_RRM_2 PF14605.6 OAP64488.1 - 0.066 13.2 0.0 0.64 10.1 0.0 2.2 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Zn_clus PF00172.18 OAP64489.1 - 6.3e-06 26.2 3.9 6.3e-06 26.2 3.9 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FeoB_associated PF12669.7 OAP64489.1 - 0.11 12.9 0.1 0.11 12.9 0.1 2.3 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein Ribosomal_S24e PF01282.19 OAP64490.1 - 3.4e-34 116.7 0.2 6e-34 115.8 0.1 1.5 1 1 0 1 1 1 1 Ribosomal protein S24e RRXRR PF14239.6 OAP64490.1 - 0.031 14.2 3.2 0.043 13.7 2.8 1.5 1 1 0 1 1 1 0 RRXRR protein Methyltransf_16 PF10294.9 OAP64491.1 - 5.8e-20 71.7 0.0 8.9e-20 71.1 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 OAP64491.1 - 0.0056 16.1 0.1 0.012 15.0 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Met_10 PF02475.16 OAP64491.1 - 0.013 15.3 0.0 0.023 14.4 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_25 PF13649.6 OAP64491.1 - 0.039 14.7 0.1 0.11 13.2 0.1 2.0 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 OAP64491.1 - 0.084 12.4 0.1 0.14 11.7 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase small domain McrBC PF10117.9 OAP64491.1 - 0.15 11.2 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 McrBC 5-methylcytosine restriction system component HSP70 PF00012.20 OAP64492.1 - 1.3e-06 26.9 0.0 2.2e-05 22.9 0.0 2.2 2 1 0 2 2 2 2 Hsp70 protein PIN_6 PF17146.4 OAP64493.1 - 0.18 12.3 0.6 22 5.6 0.0 3.8 3 0 0 3 3 3 0 PIN domain of ribonuclease HTH_32 PF13565.6 OAP64494.1 - 0.0032 18.1 0.9 0.0048 17.5 0.9 1.4 1 0 0 1 1 1 1 Homeodomain-like domain Tropomyosin_1 PF12718.7 OAP64495.1 - 0.046 13.9 34.8 0.24 11.5 27.0 3.5 2 1 0 2 2 2 0 Tropomyosin like Lebercilin PF15619.6 OAP64495.1 - 0.25 11.0 28.6 0.62 9.7 21.4 2.6 2 1 1 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease Phage_GP20 PF06810.11 OAP64495.1 - 0.32 10.8 14.8 0.45 10.3 0.4 3.3 2 1 0 3 3 3 0 Phage minor structural protein GP20 MCU PF04678.13 OAP64495.1 - 1.2 9.2 4.2 3.3 7.8 4.2 1.8 1 0 0 1 1 1 0 Mitochondrial calcium uniporter APG6_N PF17675.1 OAP64495.1 - 1.3 9.6 28.0 4.7 7.7 1.8 2.8 1 1 1 2 2 2 0 Apg6 coiled-coil region Bacillus_HBL PF05791.11 OAP64495.1 - 1.7 8.4 5.3 8.7 6.1 0.3 2.3 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) TMPIT PF07851.13 OAP64495.1 - 6.2 6.0 10.8 1.7 7.8 5.1 2.1 1 1 1 2 2 2 0 TMPIT-like protein GIT_CC PF16559.5 OAP64495.1 - 8.3 6.4 8.8 8 6.4 2.1 2.9 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor MAD PF05557.13 OAP64495.1 - 9.8 4.4 27.2 2.1 6.6 23.4 1.7 1 1 0 1 1 1 0 Mitotic checkpoint protein DnaJ PF00226.31 OAP64496.1 - 6.3e-14 51.9 0.0 1.1e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain ParcG PF10274.9 OAP64497.1 - 0.87 9.7 8.5 48 4.0 0.6 3.9 1 1 4 5 5 5 0 Parkin co-regulated protein Abhydrolase_3 PF07859.13 OAP64499.1 - 7.1e-50 169.8 0.0 9.5e-50 169.4 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAP64499.1 - 5.6e-05 23.8 2.1 5.6e-05 23.8 2.1 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family AXE1 PF05448.12 OAP64499.1 - 0.0018 17.0 0.0 0.0028 16.4 0.0 1.2 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) COesterase PF00135.28 OAP64499.1 - 0.0022 17.0 0.0 0.015 14.2 0.0 1.9 2 0 0 2 2 2 1 Carboxylesterase family Hydrolase_4 PF12146.8 OAP64499.1 - 0.018 14.3 0.0 0.038 13.2 0.0 1.5 1 1 0 1 1 1 0 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 OAP64499.1 - 0.033 13.7 0.0 0.68 9.4 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family Esterase_phd PF10503.9 OAP64499.1 - 0.13 11.7 0.1 0.23 10.9 0.1 1.3 1 0 0 1 1 1 0 Esterase PHB depolymerase DUF3328 PF11807.8 OAP64501.1 - 1.3e-35 123.2 0.0 1.6e-35 122.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.8 OAP64502.1 - 3.2e-35 121.9 0.0 4e-35 121.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) HetR_C PF18460.1 OAP64502.1 - 0.09 12.7 0.6 0.2 11.6 0.1 1.8 2 0 0 2 2 2 0 Heterocyst differentiation regulator C-terminal Hood domain Ank_4 PF13637.6 OAP64504.1 - 1.7e-19 69.9 0.5 1.2e-10 41.7 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OAP64504.1 - 7.1e-16 58.6 0.2 1.8e-12 47.7 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OAP64504.1 - 1.3e-13 50.8 5.0 2e-07 31.2 0.2 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 OAP64504.1 - 8.3e-13 48.2 2.3 3.7e-06 27.1 0.7 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 OAP64504.1 - 6.3e-11 41.5 0.4 2.9e-05 24.1 0.1 3.5 3 0 0 3 3 3 2 Ankyrin repeat Fungal_trans_2 PF11951.8 OAP64506.1 - 7.3e-07 28.3 0.2 1.1e-06 27.8 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DNApol3-delta_C PF09115.10 OAP64506.1 - 0.14 12.7 5.2 1 9.9 0.1 2.7 3 0 0 3 3 3 0 DNA polymerase III, delta subunit, C terminal GFA PF04828.14 OAP64507.1 - 1.9e-13 50.6 1.7 1.9e-13 50.6 1.7 2.1 2 0 0 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme Rubredoxin_2 PF18073.1 OAP64507.1 - 0.55 10.0 10.6 8.6 6.2 0.7 3.5 3 0 0 3 3 3 0 Rubredoxin metal binding domain Tyrosinase PF00264.20 OAP64508.1 - 1.6e-54 185.6 1.2 2e-54 185.2 1.2 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase YdjM PF04307.14 OAP64509.1 - 2.4 7.5 6.0 4.4 6.6 5.0 2.1 1 1 0 1 1 1 0 LexA-binding, inner membrane-associated putative hydrolase Pyr_redox_2 PF07992.14 OAP64510.1 - 5.1e-47 160.5 0.0 6.6e-47 160.2 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.26 OAP64510.1 - 4.5e-15 55.3 0.0 1.2e-14 54.0 0.0 1.7 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox PF00070.27 OAP64510.1 - 4.5e-14 52.8 1.4 1.7e-13 50.9 0.2 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Reductase_C PF14759.6 OAP64510.1 - 6.2e-06 26.7 0.0 1.3e-05 25.7 0.0 1.5 1 0 0 1 1 1 1 Reductase C-terminal DUF1188 PF06690.11 OAP64510.1 - 0.0011 18.6 0.0 0.0017 18.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1188) NAD_binding_9 PF13454.6 OAP64510.1 - 0.076 13.0 0.3 12 5.9 0.0 3.1 4 0 0 4 4 4 0 FAD-NAD(P)-binding TrkA_N PF02254.18 OAP64510.1 - 0.085 13.1 0.2 1.7 8.9 0.0 2.7 3 0 0 3 3 3 0 TrkA-N domain RPA43_OB PF17875.1 OAP64511.1 - 1.8e-31 109.3 7.2 3e-31 108.6 0.1 2.4 2 0 0 2 2 2 1 RPA43 OB domain in RNA Pol I SHS2_Rpb7-N PF03876.17 OAP64511.1 - 0.00025 21.3 0.0 0.00049 20.4 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Presenilin PF01080.17 OAP64511.1 - 0.16 10.7 1.1 0.6 8.8 0.8 1.9 2 0 0 2 2 2 0 Presenilin MFS_1 PF07690.16 OAP64513.1 - 6.8e-20 71.3 37.7 9.4e-12 44.5 16.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Acyl-CoA_dh_C PF12806.7 OAP64513.1 - 2.2 8.4 4.4 15 5.7 0.2 2.8 3 0 0 3 3 3 0 Acetyl-CoA dehydrogenase C-terminal like LSPR PF06049.12 OAP64514.1 - 3 8.1 4.4 10 6.5 0.4 2.8 2 0 0 2 2 2 0 Coagulation Factor V LSPD Repeat TRI12 PF06609.13 OAP64515.1 - 8.1e-33 113.7 26.3 1.1e-32 113.2 26.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAP64515.1 - 1.7e-21 76.6 49.1 1.7e-21 76.6 49.1 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily Abhydrolase_3 PF07859.13 OAP64516.1 - 9.6e-44 149.8 0.0 1.3e-43 149.4 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 OAP64516.1 - 3e-07 29.7 0.0 9.3e-07 28.1 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family DUF2236 PF09995.9 OAP64517.1 - 2.6e-10 40.9 1.2 4.6e-10 40.1 1.2 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) DUF3425 PF11905.8 OAP64518.1 - 1.6e-12 47.5 0.2 3.2e-12 46.5 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 OAP64518.1 - 6e-05 23.1 1.3 0.0001 22.3 1.3 1.4 1 0 0 1 1 1 1 bZIP transcription factor ABC_tran_Xtn PF12848.7 OAP64518.1 - 0.066 13.3 0.7 0.13 12.3 0.7 1.5 1 0 0 1 1 1 0 ABC transporter Nop14 PF04147.12 OAP64519.1 - 0.077 11.2 11.1 0.11 10.6 11.1 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 OAP64519.1 - 0.12 10.7 8.3 0.14 10.4 8.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 OAP64519.1 - 3.9 6.1 8.2 4.6 5.9 8.2 1.2 1 0 0 1 1 1 0 Presenilin SPRY PF00622.28 OAP64520.1 - 1.9e-24 86.0 0.6 3.2e-24 85.4 0.1 1.6 2 0 0 2 2 2 1 SPRY domain CLTH PF10607.9 OAP64520.1 - 2e-24 86.2 0.0 3e-24 85.6 0.0 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 OAP64520.1 - 0.00029 20.7 0.6 0.001 18.9 0.1 2.2 3 0 0 3 3 3 1 LisH Phospho_p8 PF10195.9 OAP64520.1 - 0.95 10.0 3.3 1.4 9.5 0.1 2.8 3 0 0 3 3 3 0 DNA-binding nuclear phosphoprotein p8 INO80_Ies4 PF08193.11 OAP64521.1 - 5.1e-70 236.2 21.5 5.1e-70 236.2 21.5 1.7 1 1 1 2 2 2 1 INO80 complex subunit Ies4 Mei5 PF10376.9 OAP64522.1 - 3.6e-08 33.5 0.6 4.9e-08 33.1 0.6 1.2 1 0 0 1 1 1 1 Double-strand recombination repair protein SwrA PF17423.2 OAP64522.1 - 0.0098 15.9 0.2 0.018 15.0 0.0 1.6 2 0 0 2 2 2 1 Swarming motility protein OmpH PF03938.14 OAP64522.1 - 0.18 12.1 6.9 0.18 12.1 5.9 1.4 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) FUSC PF04632.12 OAP64522.1 - 0.42 9.1 5.7 0.51 8.8 5.7 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Epimerase PF01370.21 OAP64523.1 - 1.5e-13 50.8 0.0 2.8e-13 49.9 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAP64523.1 - 3.1e-07 30.1 0.0 4.8e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 OAP64523.1 - 3.4e-07 29.7 0.0 0.0006 19.1 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 OAP64523.1 - 9.1e-05 22.4 0.0 0.00017 21.6 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 OAP64523.1 - 0.00089 18.3 0.0 0.002 17.2 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 OAP64523.1 - 0.022 13.9 0.0 0.035 13.2 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 OAP64523.1 - 0.075 13.3 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Arf PF00025.21 OAP64524.1 - 8e-39 132.9 0.3 7e-24 84.2 0.5 3.0 2 1 0 2 2 2 2 ADP-ribosylation factor family G-alpha PF00503.20 OAP64524.1 - 1.1e-11 44.5 0.0 1e-06 28.2 0.0 2.6 2 1 0 2 2 2 2 G-protein alpha subunit Roc PF08477.13 OAP64524.1 - 1.9e-10 41.0 0.0 5.9e-10 39.4 0.0 1.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 OAP64524.1 - 8.5e-08 32.0 0.1 0.00014 21.5 0.0 2.8 2 1 0 2 2 2 2 Ras family SRPRB PF09439.10 OAP64524.1 - 2.7e-06 26.9 0.4 5.6e-05 22.6 0.1 2.5 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 OAP64524.1 - 4.3e-06 26.8 0.0 1.3e-05 25.2 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OAP64524.1 - 0.00011 21.8 0.0 0.047 13.2 0.0 2.1 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OAP64524.1 - 0.0016 17.9 0.0 0.0045 16.4 0.0 1.8 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 OAP64524.1 - 0.017 14.7 0.1 0.05 13.1 0.1 1.8 2 0 0 2 2 2 0 Ferrous iron transport protein B Fungal_trans_2 PF11951.8 OAP64525.1 - 8.2e-48 163.1 2.2 1e-47 162.8 2.2 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP64525.1 - 1.8e-10 40.7 4.7 3.4e-10 39.9 4.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Arrestin_N PF00339.29 OAP64526.1 - 3.7e-11 43.3 0.1 3.9e-09 36.7 0.0 3.1 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Bul1_C PF04426.12 OAP64526.1 - 0.04 13.3 0.0 0.073 12.5 0.0 1.3 1 0 0 1 1 1 0 Bul1 C terminus RSN1_7TM PF02714.15 OAP64527.1 - 7.4e-82 274.7 24.8 1.2e-81 274.1 24.8 1.3 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 OAP64527.1 - 3e-39 134.3 1.8 3e-39 134.3 1.8 2.4 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 OAP64527.1 - 9e-26 91.2 0.0 1.5e-25 90.4 0.0 1.4 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 OAP64527.1 - 5.6e-21 74.5 0.1 1.2e-20 73.5 0.1 1.5 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter RRM_1 PF00076.22 OAP64527.1 - 0.069 13.0 0.0 0.22 11.4 0.0 1.8 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Dor1 PF04124.12 OAP64527.1 - 0.11 11.1 0.0 0.2 10.3 0.0 1.3 1 0 0 1 1 1 0 Dor1-like family Mfa_like_1 PF13149.6 OAP64528.1 - 1.2 9.1 6.7 0.69 9.9 0.7 2.0 1 1 1 2 2 2 0 Fimbrillin-like Pyr_redox_3 PF13738.6 OAP64529.1 - 4.1e-13 49.3 0.0 5.1e-12 45.7 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 OAP64529.1 - 4.2e-11 42.0 0.0 7.3e-11 41.2 0.0 1.3 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 OAP64529.1 - 4.1e-08 32.7 0.0 4.4e-07 29.4 0.0 2.3 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 OAP64529.1 - 1.6e-06 27.5 0.0 0.00012 21.4 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAP64529.1 - 0.00052 20.0 0.0 1.1 9.3 0.0 3.3 2 1 0 2 2 2 2 FAD-NAD(P)-binding Sugar_tr PF00083.24 OAP64530.1 - 1.2e-84 284.8 20.5 1.4e-84 284.6 20.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP64530.1 - 1.6e-25 89.8 32.1 1.3e-19 70.4 14.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 OAP64530.1 - 1.4e-05 24.6 2.9 1.4e-05 24.6 2.9 2.2 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 OAP64530.1 - 0.014 13.8 8.2 0.039 12.3 6.9 2.1 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family TRI12 PF06609.13 OAP64530.1 - 0.31 9.4 11.1 0.031 12.7 5.3 1.9 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAP64531.1 - 3.2e-24 85.5 40.8 3.2e-24 85.5 40.8 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Glyco_trans_2_3 PF13632.6 OAP64532.1 - 4.4e-19 69.2 0.2 4.4e-19 69.2 0.2 1.9 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 OAP64532.1 - 3.3e-14 53.0 0.0 5.5e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 OAP64532.1 - 3.8e-14 53.1 0.0 6e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 OAP64532.1 - 4e-12 45.9 0.0 7.9e-12 45.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 21 Cellulose_synt PF03552.14 OAP64532.1 - 3.4e-11 42.4 0.1 5e-05 22.0 0.3 2.8 1 1 2 3 3 3 2 Cellulose synthase Chitin_synth_2 PF03142.15 OAP64532.1 - 0.16 10.6 0.7 1.6 7.3 0.2 2.2 2 0 0 2 2 2 0 Chitin synthase TauD PF02668.16 OAP64533.1 - 6e-64 216.4 0.2 7.5e-64 216.1 0.2 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.16 OAP64534.1 - 4.9e-37 127.7 10.8 4.9e-37 127.7 10.8 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 OAP64534.1 - 2.3e-06 27.2 0.5 2.3e-06 27.2 0.5 2.0 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB CENP-I PF07778.11 OAP64534.1 - 0.1 11.3 0.2 0.15 10.7 0.2 1.1 1 0 0 1 1 1 0 Mis6 FMO-like PF00743.19 OAP64535.1 - 1.2e-40 139.4 0.0 1.2e-20 73.4 0.0 3.2 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OAP64535.1 - 3.1e-16 59.5 0.0 1.1e-11 44.6 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAP64535.1 - 5.1e-12 46.0 3.6 1.4e-06 28.1 1.8 3.2 3 0 0 3 3 3 3 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAP64535.1 - 2e-10 40.4 0.0 2e-09 37.1 0.0 2.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAP64535.1 - 1.9e-09 37.7 4.3 6.6e-05 22.9 0.2 3.8 4 0 0 4 4 4 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 OAP64535.1 - 1.1e-07 32.0 0.1 6.7e-07 29.5 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 OAP64535.1 - 1.3e-06 27.8 0.8 0.0002 20.6 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Amino_oxidase PF01593.24 OAP64535.1 - 4.9e-06 26.1 0.1 0.01 15.1 0.1 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 OAP64535.1 - 0.00011 21.8 0.5 0.00046 19.6 0.2 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Shikimate_DH PF01488.20 OAP64535.1 - 0.00011 22.2 0.1 0.027 14.5 0.3 2.5 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.24 OAP64535.1 - 0.0012 18.0 0.7 0.0085 15.2 0.3 2.4 3 0 0 3 3 3 1 FAD binding domain Thi4 PF01946.17 OAP64535.1 - 0.0021 17.3 0.3 0.0039 16.5 0.3 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 OAP64535.1 - 0.0048 17.4 4.0 0.0086 16.6 0.6 2.8 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAP64535.1 - 0.0049 15.6 1.4 0.029 13.1 1.1 2.2 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.19 OAP64535.1 - 0.012 14.9 0.6 0.029 13.6 0.6 1.6 1 0 0 1 1 1 0 FAD binding domain 3HCDH_N PF02737.18 OAP64535.1 - 0.016 15.1 0.8 0.036 13.9 0.8 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 OAP64535.1 - 0.043 13.1 0.5 0.12 11.6 0.3 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 OAP64535.1 - 0.043 12.9 0.6 0.1 11.7 0.7 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A IlvN PF07991.12 OAP64535.1 - 0.084 12.4 0.1 0.17 11.5 0.1 1.5 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_2 PF03446.15 OAP64535.1 - 0.15 12.2 0.1 0.62 10.2 0.1 2.0 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.16 OAP64535.1 - 0.44 10.2 1.6 1.4 8.6 1.6 1.8 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Tom6 PF17112.5 OAP64536.1 - 0.012 15.1 0.3 0.017 14.6 0.3 1.2 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom6, fungal MFS_1 PF07690.16 OAP64537.1 - 1.2e-14 54.1 14.4 1.2e-14 54.1 14.4 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily TatC PF00902.18 OAP64537.1 - 0.013 15.3 1.5 0.013 15.3 1.5 3.2 2 1 0 2 2 2 0 Sec-independent protein translocase protein (TatC) S_4TM PF18159.1 OAP64537.1 - 0.72 9.1 6.1 0.77 9.0 0.0 2.9 3 0 0 3 3 3 0 SMODS-associating 4TM effector domain MARVEL PF01284.23 OAP64538.1 - 1e-07 32.1 11.4 2.4e-07 30.9 11.4 1.6 1 1 0 1 1 1 1 Membrane-associating domain DUF3561 PF12084.8 OAP64538.1 - 0.032 14.3 2.9 0.062 13.3 2.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3561) Methyltransf_23 PF13489.6 OAP64539.1 - 3.8e-09 36.6 0.0 5.2e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAP64539.1 - 4.3e-06 27.3 0.0 1.9e-05 25.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAP64539.1 - 0.00013 22.6 0.0 0.00033 21.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAP64539.1 - 0.00015 22.4 0.0 0.0003 21.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAP64539.1 - 0.0084 15.9 0.1 0.091 12.6 0.1 2.1 1 1 0 1 1 1 1 Methyltransferase domain Waikav_capsid_1 PF12264.8 OAP64539.1 - 0.055 13.0 0.0 0.083 12.4 0.0 1.2 1 0 0 1 1 1 0 Waikavirus capsid protein 1 Methyltransf_31 PF13847.6 OAP64540.1 - 3.8e-09 36.5 0.0 1.1e-08 35.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAP64540.1 - 8.9e-09 35.4 0.0 1.3e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAP64540.1 - 1.3e-06 29.0 0.0 3e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAP64540.1 - 1.3e-05 25.8 0.0 3.2e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAP64540.1 - 8.3e-05 23.2 0.0 0.00026 21.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain CheR PF01739.18 OAP64540.1 - 0.00037 20.0 0.0 0.00066 19.2 0.0 1.5 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain DUF4943 PF16301.5 OAP64540.1 - 0.079 13.0 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4943) MTS PF05175.14 OAP64540.1 - 0.11 12.0 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain GFA PF04828.14 OAP64541.1 - 4.8e-20 71.7 0.1 4.8e-20 71.7 0.1 1.5 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme MNHE PF01899.16 OAP64542.1 - 0.29 10.9 3.2 4 7.2 0.0 2.4 2 0 0 2 2 2 0 Na+/H+ ion antiporter subunit FixP_N PF14715.6 OAP64542.1 - 7 6.5 7.4 1.6 8.6 0.1 3.4 3 0 0 3 3 3 0 N-terminal domain of cytochrome oxidase-cbb3, FixP SSP160 PF06933.11 OAP64542.1 - 7.4 4.6 9.0 10 4.2 9.0 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF1899 PF08953.11 OAP64543.1 - 2.7e-35 120.1 0.0 5.1e-35 119.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 OAP64543.1 - 1.3e-19 69.8 0.1 2.3e-19 69.0 0.1 1.5 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 OAP64543.1 - 1.5e-18 66.8 4.0 0.00025 21.8 0.1 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAP64543.1 - 4.6e-08 33.3 0.0 0.0018 18.6 0.0 3.2 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain BRE1 PF08647.11 OAP64543.1 - 0.015 15.4 1.3 0.027 14.6 1.3 1.4 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase Nup160 PF11715.8 OAP64543.1 - 0.063 11.9 0.1 0.29 9.7 0.1 1.9 1 1 1 2 2 2 0 Nucleoporin Nup120/160 FlaC_arch PF05377.11 OAP64543.1 - 0.15 12.5 1.4 0.4 11.1 1.4 1.7 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) eIF2A PF08662.11 OAP64543.1 - 0.15 11.9 0.0 2.5 7.9 0.0 2.4 1 1 2 3 3 3 0 Eukaryotic translation initiation factor eIF2A FAM76 PF16046.5 OAP64543.1 - 0.52 9.6 3.6 0.43 9.9 1.8 1.6 2 0 0 2 2 2 0 FAM76 protein NYAP_C PF15452.6 OAP64544.1 - 0.018 14.9 0.8 0.021 14.7 0.8 1.0 1 0 0 1 1 1 0 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter DUF4611 PF15387.6 OAP64544.1 - 0.25 11.6 4.1 0.35 11.1 4.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4611) APH PF01636.23 OAP64545.1 - 2.7e-11 43.9 1.6 1e-10 42.0 0.0 2.7 2 1 0 2 2 2 1 Phosphotransferase enzyme family Nucleoporin_C PF03177.14 OAP64545.1 - 0.03 13.1 0.3 0.059 12.1 0.3 1.4 1 0 0 1 1 1 0 Non-repetitive/WGA-negative nucleoporin C-terminal Aldo_ket_red PF00248.21 OAP64546.1 - 7e-70 235.5 0.0 8e-70 235.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family McrBC PF10117.9 OAP64546.1 - 0.17 11.0 0.0 0.25 10.4 0.0 1.2 1 0 0 1 1 1 0 McrBC 5-methylcytosine restriction system component F_actin_cap_B PF01115.17 OAP64547.1 - 1.3e-99 332.7 0.0 1.5e-99 332.5 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit Fungal_trans PF04082.18 OAP64548.1 - 2.5e-10 39.8 1.7 3.6e-10 39.3 1.7 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP64548.1 - 8.6e-10 38.6 8.4 8.6e-10 38.6 8.4 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LAT PF15234.6 OAP64549.1 - 0.016 15.0 1.6 0.025 14.3 1.6 1.2 1 0 0 1 1 1 0 Linker for activation of T-cells RXT2_N PF08595.11 OAP64549.1 - 0.2 11.7 1.9 0.32 11.0 1.9 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal FAM176 PF14851.6 OAP64549.1 - 0.28 10.8 2.4 0.52 10.0 2.4 1.3 1 0 0 1 1 1 0 FAM176 family NOA36 PF06524.12 OAP64549.1 - 0.51 9.6 5.0 0.75 9.1 5.0 1.1 1 0 0 1 1 1 0 NOA36 protein Pox_Ag35 PF03286.14 OAP64549.1 - 0.56 10.0 4.4 0.89 9.3 4.4 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF1772 PF08592.11 OAP64550.1 - 0.00089 19.6 3.1 0.0026 18.1 3.1 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) Patatin PF01734.22 OAP64551.1 - 1.9e-19 70.6 0.0 4.3e-19 69.5 0.0 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase zf-C3HC4_3 PF13920.6 OAP64551.1 - 0.00055 19.7 3.4 0.0014 18.5 3.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) MMR_HSR1 PF01926.23 OAP64551.1 - 0.0037 17.3 0.0 0.44 10.7 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase zf-C3HC4 PF00097.25 OAP64551.1 - 0.0041 17.0 5.0 0.01 15.7 5.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAP64551.1 - 0.011 15.7 7.1 0.042 13.9 7.1 2.0 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OAP64551.1 - 0.012 15.5 4.2 0.027 14.3 4.2 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) AAA_29 PF13555.6 OAP64551.1 - 0.015 15.0 0.1 0.034 13.9 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 OAP64551.1 - 0.017 15.0 0.1 0.069 13.0 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase zf-RING_2 PF13639.6 OAP64551.1 - 0.055 13.8 5.9 0.14 12.5 5.9 1.8 1 0 0 1 1 1 0 Ring finger domain AAA_16 PF13191.6 OAP64551.1 - 0.064 13.6 0.0 0.17 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 OAP64551.1 - 0.081 13.4 0.0 0.21 12.1 0.0 1.6 1 0 0 1 1 1 0 ABC transporter zf-RING_5 PF14634.6 OAP64551.1 - 0.13 12.2 5.9 0.35 10.9 5.9 1.8 1 0 0 1 1 1 0 zinc-RING finger domain zf-HYPF PF07503.12 OAP64551.1 - 0.37 10.6 1.9 0.82 9.5 0.3 2.4 2 0 0 2 2 2 0 HypF finger zf-C3HC4_4 PF15227.6 OAP64551.1 - 2.8 8.2 7.1 7.7 6.8 7.1 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING AA_permease PF00324.21 OAP64552.1 - 2.9e-67 227.3 29.3 1.5e-64 218.4 24.1 2.1 2 0 0 2 2 2 2 Amino acid permease AA_permease_2 PF13520.6 OAP64552.1 - 6.3e-24 84.6 34.0 8.5e-24 84.2 33.4 1.5 1 1 0 1 1 1 1 Amino acid permease adh_short_C2 PF13561.6 OAP64554.1 - 4.6e-38 131.1 1.1 5.3e-37 127.6 1.1 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP64554.1 - 3e-29 101.9 0.9 6.7e-29 100.7 0.9 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAP64554.1 - 2.3e-05 24.4 0.7 5.5e-05 23.2 0.3 1.6 1 1 1 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 OAP64554.1 - 0.038 13.1 0.1 0.053 12.7 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF3402 PF11882.8 OAP64555.1 - 2.7e-172 574.0 0.0 3.7e-172 573.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.13 OAP64555.1 - 5.2e-78 262.2 0.1 7.9e-78 261.6 0.1 1.3 1 0 0 1 1 1 1 N1221-like protein Fungal_trans_2 PF11951.8 OAP64556.1 - 6.3e-37 127.3 6.0 7.4e-37 127.1 6.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP64556.1 - 7.2e-06 26.0 7.3 1.8e-05 24.8 7.3 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aminotran_3 PF00202.21 OAP64557.1 - 8.8e-69 232.1 0.0 1.1e-68 231.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 OAP64557.1 - 0.025 13.9 0.0 0.068 12.4 0.0 1.7 1 1 0 1 1 1 0 Beta-eliminating lyase Amidase PF01425.21 OAP64558.1 - 2.4e-97 326.8 0.0 3.4e-97 326.2 0.0 1.2 1 0 0 1 1 1 1 Amidase UNC-93 PF05978.16 OAP64559.1 - 3.6e-09 36.5 1.6 3.6e-09 36.5 1.6 2.6 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 OAP64559.1 - 8.2e-07 28.3 32.3 2.6e-05 23.3 32.3 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Peptidase_M48_N PF16491.5 OAP64559.1 - 0.59 10.0 4.6 0.18 11.6 0.3 2.3 2 0 0 2 2 2 0 CAAX prenyl protease N-terminal, five membrane helices Med11 PF10280.9 OAP64560.1 - 1.2e-28 100.3 0.0 1.5e-28 100.0 0.0 1.1 1 0 0 1 1 1 1 Mediator complex protein WD40 PF00400.32 OAP64561.1 - 2e-41 139.2 25.1 9.9e-07 29.4 0.4 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 OAP64561.1 - 4.1e-35 120.9 0.4 4.1e-35 120.9 0.4 1.5 2 0 0 2 2 2 1 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.7 OAP64561.1 - 5.5e-09 36.2 0.6 0.038 14.3 0.0 4.6 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 OAP64561.1 - 0.0019 18.1 0.5 0.012 15.6 0.0 2.5 3 0 0 3 3 3 1 LisH eIF2A PF08662.11 OAP64561.1 - 0.002 18.1 0.1 0.0044 16.9 0.1 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 OAP64561.1 - 0.002 16.9 0.4 0.082 11.5 0.1 2.3 2 0 0 2 2 2 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 OAP64561.1 - 0.0077 15.0 0.0 15 4.2 0.0 4.0 3 1 2 5 5 5 1 Nup133 N terminal like POTRA_TamA_1 PF17243.2 OAP64561.1 - 0.01 15.9 0.8 0.028 14.5 0.8 1.7 1 0 0 1 1 1 0 POTRA domain TamA domain 1 DUF4550 PF15084.6 OAP64561.1 - 0.15 12.5 0.1 0.53 10.7 0.1 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4550) Rhomboid PF01694.22 OAP64562.1 - 9.5e-21 74.4 4.7 1.1e-20 74.1 4.7 1.1 1 0 0 1 1 1 1 Rhomboid family DUF4153 PF13687.6 OAP64562.1 - 0.041 13.5 0.4 0.061 13.0 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4153) HDA2-3 PF11496.8 OAP64563.1 - 4.4e-14 52.3 0.1 4.4e-14 52.3 0.1 3.1 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 Chromo PF00385.24 OAP64563.1 - 0.014 15.3 0.8 0.04 13.8 0.8 1.9 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain BLOC1_2 PF10046.9 OAP64563.1 - 0.12 12.7 10.9 0.054 13.8 1.8 3.7 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FMO-like PF00743.19 OAP64564.1 - 7.3e-44 150.1 0.0 6.6e-29 100.7 0.0 3.0 2 1 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OAP64564.1 - 1.8e-12 47.1 0.7 1.7e-08 34.1 0.0 3.4 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAP64564.1 - 1.6e-09 37.4 0.2 4.6e-08 32.7 0.2 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAP64564.1 - 2.1e-08 33.7 0.1 1.7e-05 24.2 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 OAP64564.1 - 3.8e-08 33.3 2.6 0.015 14.9 0.7 3.1 3 0 0 3 3 3 3 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 OAP64564.1 - 6.8e-08 32.7 0.1 3e-06 27.3 0.0 2.9 3 0 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 OAP64564.1 - 2.8e-05 24.3 0.1 8e-05 22.8 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 OAP64564.1 - 0.00012 21.4 0.5 0.051 12.8 0.1 2.4 2 0 0 2 2 2 2 Thi4 family Pyr_redox PF00070.27 OAP64564.1 - 0.0044 17.6 1.1 0.41 11.2 0.1 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAP64564.1 - 0.0089 14.8 0.0 0.41 9.3 0.1 2.7 3 0 0 3 3 3 1 HI0933-like protein Amino_oxidase PF01593.24 OAP64564.1 - 0.046 13.0 0.2 0.51 9.6 0.0 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase NAD_binding_7 PF13241.6 OAP64564.1 - 0.087 13.3 0.1 8.3 6.9 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding Shikimate_DH PF01488.20 OAP64564.1 - 0.13 12.3 0.0 3.9 7.5 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Abhydrolase_5 PF12695.7 OAP64565.1 - 1.4e-05 24.9 0.0 0.00021 21.1 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 OAP64565.1 - 0.024 14.8 0.0 0.061 13.4 0.0 1.7 1 0 0 1 1 1 0 TAP-like protein DLH PF01738.18 OAP64565.1 - 0.031 13.8 0.0 0.048 13.2 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family PhzC-PhzF PF02567.16 OAP64569.1 - 7e-38 130.7 0.0 1e-37 130.2 0.0 1.2 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Pro_racemase PF05544.11 OAP64569.1 - 0.0038 16.3 0.0 0.0068 15.5 0.0 1.4 1 0 0 1 1 1 1 Proline racemase Pilus_CpaD PF09476.10 OAP64569.1 - 0.054 13.2 0.9 0.47 10.2 0.1 2.1 2 0 0 2 2 2 0 Pilus biogenesis CpaD protein (pilus_cpaD) CMD PF02627.20 OAP64570.1 - 5.9e-05 23.0 0.0 0.18 11.9 0.0 2.3 2 0 0 2 2 2 2 Carboxymuconolactone decarboxylase family DUF2407_C PF13373.6 OAP64570.1 - 0.2 11.8 0.0 0.4 10.8 0.0 1.5 1 0 0 1 1 1 0 DUF2407 C-terminal domain UPF0061 PF02696.14 OAP64571.1 - 2.9e-126 422.0 0.0 3.8e-126 421.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family GAS PF13851.6 OAP64572.1 - 2.3e-06 27.1 307.5 5e-05 22.8 13.3 15.4 1 1 11 13 13 13 8 Growth-arrest specific micro-tubule binding JIP_LZII PF16471.5 OAP64572.1 - 0.00022 21.3 6.7 0.00022 21.3 6.7 24.0 11 8 12 26 26 26 1 JNK-interacting protein leucine zipper II FPP PF05911.11 OAP64572.1 - 0.00091 17.5 37.5 0.00091 17.5 37.5 10.9 1 1 10 11 11 11 6 Filament-like plant protein, long coiled-coil Spc7 PF08317.11 OAP64572.1 - 0.0014 17.6 346.1 0.0048 15.8 20.4 14.8 1 1 15 16 16 16 12 Spc7 kinetochore protein DHR10 PF18595.1 OAP64572.1 - 0.0075 16.3 15.9 0.0075 16.3 15.9 18.7 1 1 15 18 18 18 6 Designed helical repeat protein 10 domain Filament PF00038.21 OAP64572.1 - 1.7 8.2 294.1 0.1 12.1 34.1 10.1 1 1 7 9 9 9 0 Intermediate filament protein Amidohydro_2 PF04909.14 OAP64573.1 - 6.7e-35 121.3 0.0 8.3e-35 121.0 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase RNR_N PF08343.10 OAP64573.1 - 0.16 12.0 0.4 5.4 7.1 0.0 2.3 2 0 0 2 2 2 0 Ribonucleotide reductase N-terminal Fungal_trans PF04082.18 OAP64574.1 - 6.2e-19 68.1 0.1 9.7e-19 67.4 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP64574.1 - 2.2e-05 24.5 9.9 3.7e-05 23.8 9.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF932 PF06067.11 OAP64574.1 - 0.058 13.2 0.3 0.1 12.3 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF932) Sugar_tr PF00083.24 OAP64575.1 - 7e-83 279.0 27.4 8.4e-83 278.7 27.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP64575.1 - 1.6e-16 60.2 40.7 1.7e-11 43.7 21.7 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Dabb PF07876.12 OAP64576.1 - 4.6e-18 65.6 0.2 5.4e-18 65.4 0.2 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain DUF5039 PF16442.5 OAP64577.1 - 0.035 13.7 0.1 0.048 13.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5039) PhyH PF05721.13 OAP64578.1 - 3.3e-11 43.8 0.0 5e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Acyl_transf_3 PF01757.22 OAP64579.1 - 4.4e-27 95.0 28.6 7.1e-27 94.4 28.6 1.3 1 0 0 1 1 1 1 Acyltransferase family ENOD93 PF03386.14 OAP64579.1 - 0.073 13.0 0.2 0.17 11.8 0.2 1.6 1 0 0 1 1 1 0 Early nodulin 93 ENOD93 protein Stimulus_sens_1 PF13756.6 OAP64579.1 - 0.1 13.2 0.2 0.41 11.2 0.2 1.9 1 1 0 1 1 1 0 Stimulus-sensing domain Meth_synt_2 PF01717.18 OAP64580.1 - 2.3e-11 43.6 0.0 1.1e-10 41.3 0.0 1.9 1 1 0 1 1 1 1 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 OAP64580.1 - 0.00025 20.7 0.0 0.014 15.0 0.0 2.2 2 0 0 2 2 2 2 Cobalamin-independent synthase, N-terminal domain RTA1 PF04479.13 OAP64581.1 - 2.5e-17 63.2 6.5 3e-17 62.9 6.5 1.0 1 0 0 1 1 1 1 RTA1 like protein bZIP_1 PF00170.21 OAP64583.1 - 0.00012 22.1 12.3 0.0002 21.4 11.8 1.6 1 1 1 2 2 2 1 bZIP transcription factor GAS PF13851.6 OAP64583.1 - 0.002 17.5 6.2 0.0027 17.1 6.2 1.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Tropomyosin_1 PF12718.7 OAP64583.1 - 0.0029 17.8 3.3 0.0037 17.4 3.3 1.1 1 0 0 1 1 1 1 Tropomyosin like TACC_C PF05010.14 OAP64583.1 - 0.0035 17.1 0.8 0.0045 16.8 0.8 1.0 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF3450 PF11932.8 OAP64583.1 - 0.036 13.4 2.9 0.048 13.0 2.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) V_ATPase_I PF01496.19 OAP64583.1 - 0.11 10.5 0.9 0.12 10.3 0.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PI_PP_I PF18363.1 OAP64583.1 - 0.18 12.0 0.1 0.25 11.6 0.1 1.2 1 0 0 1 1 1 0 Phosphoinositide phosphatase insertion domain bZIP_2 PF07716.15 OAP64583.1 - 0.36 11.0 15.6 0.13 12.4 9.8 2.0 2 0 0 2 2 2 0 Basic region leucine zipper bZIP_Maf PF03131.17 OAP64583.1 - 1 9.9 12.4 1.4 9.5 11.5 1.6 1 1 1 2 2 2 0 bZIP Maf transcription factor HSCB_C PF07743.13 OAP64583.1 - 1.1 9.8 5.7 3.2 8.3 0.1 2.1 1 1 1 2 2 2 0 HSCB C-terminal oligomerisation domain PIG-P PF08510.12 OAP64584.1 - 2.2e-52 176.1 0.9 6.6e-52 174.5 0.9 1.8 1 1 0 1 1 1 1 PIG-P DUF2417 PF10329.9 OAP64584.1 - 0.11 11.9 0.1 0.17 11.2 0.1 1.2 1 0 0 1 1 1 0 Region of unknown function (DUF2417) DPM2 PF07297.12 OAP64584.1 - 0.58 10.5 10.3 0.99 9.8 10.3 1.3 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) BSP_II PF05432.11 OAP64585.1 - 0.34 10.6 3.7 0.63 9.7 3.7 1.4 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Peptidase_S28 PF05577.12 OAP64586.1 - 2.5e-46 158.4 0.4 1.8e-37 129.2 0.0 2.1 2 0 0 2 2 2 2 Serine carboxypeptidase S28 adh_short PF00106.25 OAP64587.1 - 5e-35 120.7 0.4 1.2e-34 119.5 0.0 1.8 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP64587.1 - 1.5e-30 106.5 0.5 6.8e-30 104.4 0.5 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP64587.1 - 1.6e-07 31.5 0.6 1.7e-05 24.8 0.1 2.3 2 0 0 2 2 2 2 KR domain p450 PF00067.22 OAP64588.1 - 2.9e-55 187.8 0.0 3.4e-55 187.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SnoaL PF07366.12 OAP64589.1 - 0.0061 16.4 0.3 0.023 14.5 0.1 1.8 2 0 0 2 2 2 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 OAP64589.1 - 0.21 12.2 0.4 3.5 8.3 0.4 2.1 1 1 0 1 1 1 0 SnoaL-like domain FAD_binding_3 PF01494.19 OAP64590.1 - 4.1e-63 213.7 0.0 6.6e-63 213.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAP64590.1 - 0.00016 21.3 0.0 0.0011 18.6 0.0 2.1 1 1 0 2 2 2 1 FAD dependent oxidoreductase Phe_hydrox_dim PF07976.12 OAP64590.1 - 0.00039 20.5 0.0 0.00097 19.2 0.0 1.7 1 1 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox_2 PF07992.14 OAP64590.1 - 0.00054 19.3 0.1 0.0022 17.3 0.0 2.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAP64590.1 - 0.0048 17.4 0.0 0.019 15.5 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAP64590.1 - 0.022 15.0 0.0 0.062 13.5 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Amidohydro_1 PF01979.20 OAP64591.1 - 1.5e-23 83.7 0.0 2.2e-23 83.1 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 OAP64591.1 - 1.7e-11 44.3 0.0 6.7e-06 25.8 0.0 2.6 3 0 0 3 3 3 2 Amidohydrolase family Preseq_ALAS PF09029.10 OAP64591.1 - 0.077 13.5 0.0 0.15 12.5 0.0 1.4 1 0 0 1 1 1 0 5-aminolevulinate synthase presequence Usp PF00582.26 OAP64591.1 - 0.13 12.8 0.1 0.39 11.2 0.2 1.7 2 0 0 2 2 2 0 Universal stress protein family 2OG-FeII_Oxy PF03171.20 OAP64593.1 - 2.1e-12 47.4 0.0 4.2e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 OAP64593.1 - 3.3e-08 34.3 0.0 7.3e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Sugar_tr PF00083.24 OAP64594.1 - 2.7e-86 290.2 16.0 3.3e-86 290.0 16.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP64594.1 - 1.2e-29 103.3 19.5 1.2e-29 103.3 19.5 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 OAP64594.1 - 3 6.2 10.5 0.022 13.2 1.5 1.8 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) ABA_WDS PF02496.16 OAP64595.1 - 0.0005 20.5 5.2 0.0005 20.5 5.2 3.2 1 1 2 3 3 3 1 ABA/WDS induced protein PARP PF00644.20 OAP64595.1 - 0.0035 16.9 0.1 0.0047 16.5 0.1 1.1 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain SLAIN PF15301.6 OAP64595.1 - 0.061 12.6 0.5 0.066 12.4 0.5 1.1 1 0 0 1 1 1 0 SLAIN motif-containing family SelP_N PF04592.14 OAP64595.1 - 0.1 12.0 9.9 0.13 11.6 9.9 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Zip PF02535.22 OAP64595.1 - 0.61 9.3 3.8 0.63 9.2 3.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF755 PF05501.11 OAP64595.1 - 1.4 9.2 5.9 2.2 8.6 5.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF755) CbtA PF09490.10 OAP64595.1 - 9.8 5.9 7.2 13 5.4 6.8 1.4 1 1 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) HSP20 PF00011.21 OAP64596.1 - 1.9e-11 44.0 0.0 2.3e-09 37.3 0.0 2.3 2 0 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 OAP64596.1 - 0.00076 19.0 0.1 0.0038 16.8 0.0 2.1 2 1 0 2 2 2 1 HSP20-like domain found in ArsA DUF2985 PF11204.8 OAP64599.1 - 1.8e-21 76.1 1.9 3.6e-21 75.1 1.9 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) Dicty_REP PF05086.12 OAP64599.1 - 2.1 6.2 6.2 3.5 5.5 6.2 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein PhyH PF05721.13 OAP64600.1 - 3.8e-27 95.9 0.0 5.2e-27 95.5 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) UDPG_MGDP_dh_N PF03721.14 OAP64601.1 - 4.2e-44 150.4 0.0 3.4e-28 98.5 0.0 2.3 2 0 0 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.19 OAP64601.1 - 1.2e-31 108.8 0.0 2.1e-31 108.0 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.15 OAP64601.1 - 2.8e-21 75.9 0.0 3.8e-18 65.8 0.0 2.5 2 0 0 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain NAD_binding_2 PF03446.15 OAP64601.1 - 0.014 15.6 0.0 2.7 8.1 0.0 2.5 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.16 OAP64601.1 - 0.027 14.1 0.0 0.05 13.2 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Cellsynth_D PF03500.13 OAP64601.1 - 0.03 14.2 0.0 0.069 13.0 0.0 1.5 1 0 0 1 1 1 0 Cellulose synthase subunit D Sacchrp_dh_NADP PF03435.18 OAP64601.1 - 0.032 14.5 0.0 0.077 13.3 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain 3HCDH_N PF02737.18 OAP64601.1 - 0.087 12.7 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Glycos_transf_1 PF00534.20 OAP64602.1 - 2.5e-34 118.3 0.0 4.2e-34 117.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 OAP64602.1 - 2.3e-28 99.3 0.0 6.7e-28 97.8 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 OAP64602.1 - 2.5e-13 50.4 0.0 8.6e-13 48.6 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 OAP64602.1 - 2.8e-13 50.6 0.0 1e-12 48.8 0.0 2.0 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 OAP64602.1 - 1.8e-07 31.4 0.0 4.8e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 GlgS PF08971.11 OAP64602.1 - 0.07 13.2 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Glycogen synthesis protein Glyco_trans_4_2 PF13477.6 OAP64602.1 - 0.075 13.1 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase 4-like Fungal_trans_2 PF11951.8 OAP64603.1 - 7.4e-14 51.4 0.1 1.2e-13 50.6 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Tau95_N PF17682.1 OAP64604.1 - 2.2e-34 118.4 0.0 3.5e-34 117.7 0.0 1.3 1 0 0 1 1 1 1 Tau95 Triple barrel domain B56 PF01603.20 OAP64605.1 - 2.5e-192 639.4 8.0 3.1e-192 639.1 8.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Sec7_N PF12783.7 OAP64605.1 - 0.0027 17.6 2.0 0.72 9.7 0.0 2.5 2 0 0 2 2 2 2 Guanine nucleotide exchange factor in Golgi transport N-terminal SPX PF03105.19 OAP64605.1 - 9 6.1 19.7 5 6.9 12.5 2.3 2 0 0 2 2 2 0 SPX domain FAT PF02259.23 OAP64606.1 - 8.7e-74 248.8 9.5 1.9e-73 247.7 9.5 1.6 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.27 OAP64606.1 - 4.8e-30 105.2 0.3 1.7e-29 103.4 0.0 2.2 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 OAP64606.1 - 2.1e-06 27.4 0.1 5.2e-06 26.2 0.1 1.7 1 0 0 1 1 1 1 FATC domain DUF844 PF05815.11 OAP64606.1 - 0.087 12.0 0.9 1.2 8.2 0.2 2.7 2 0 0 2 2 2 0 Baculovirus protein of unknown function (DUF844) Vezatin PF12632.7 OAP64606.1 - 0.15 11.4 3.3 0.78 9.1 1.0 2.6 2 0 0 2 2 2 0 Mysoin-binding motif of peroxisomes ANAPC3 PF12895.7 OAP64607.1 - 1.9e-22 79.3 18.7 6.8e-21 74.3 1.4 5.6 5 1 0 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 OAP64607.1 - 3.7e-20 70.3 20.8 0.0083 16.2 0.1 9.6 10 0 0 10 10 9 6 Tetratricopeptide repeat TPR_1 PF00515.28 OAP64607.1 - 1.4e-19 69.0 10.8 0.003 17.3 0.1 8.5 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_19 PF14559.6 OAP64607.1 - 1.2e-18 67.3 11.0 0.00036 21.0 0.0 6.1 5 1 1 6 6 6 5 Tetratricopeptide repeat TPR_12 PF13424.6 OAP64607.1 - 1.1e-16 60.9 24.4 4e-08 33.4 0.1 9.2 7 3 2 9 9 9 3 Tetratricopeptide repeat TPR_10 PF13374.6 OAP64607.1 - 6.5e-11 41.7 12.0 0.00017 21.3 0.1 8.0 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_8 PF13181.6 OAP64607.1 - 9.2e-11 41.1 8.4 0.31 11.4 0.0 7.1 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.6 OAP64607.1 - 2.7e-10 40.7 18.4 0.26 11.9 1.3 7.7 8 1 0 8 8 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 OAP64607.1 - 4.9e-10 39.4 14.6 0.46 11.4 0.2 9.6 8 2 2 10 10 10 2 Tetratricopeptide repeat TPR_11 PF13414.6 OAP64607.1 - 2.9e-09 36.5 1.2 0.35 10.6 0.1 6.3 6 0 0 6 6 6 1 TPR repeat TPR_7 PF13176.6 OAP64607.1 - 7.3e-08 31.9 9.8 0.42 10.8 0.0 7.6 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_6 PF13174.6 OAP64607.1 - 5.2e-07 29.9 9.1 0.36 11.5 0.1 6.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_4 PF07721.14 OAP64607.1 - 0.0018 18.7 1.5 0.084 13.5 0.2 5.8 6 0 0 6 6 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 OAP64607.1 - 0.028 14.8 3.9 32 5.2 0.0 6.4 7 0 0 7 7 6 0 Tetratricopeptide repeat DUF5005 PF16396.5 OAP64607.1 - 0.15 10.7 0.0 0.31 9.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5005) PPR PF01535.20 OAP64607.1 - 0.42 11.0 1.7 20 5.7 0.0 3.5 4 0 0 4 4 3 0 PPR repeat Fis1_TPR_C PF14853.6 OAP64607.1 - 1.9 8.6 8.8 9.2 6.4 0.6 4.1 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat DUF572 PF04502.13 OAP64608.1 - 2.4e-69 234.5 14.8 2.9e-69 234.3 14.8 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) zf-ACC PF17848.1 OAP64608.1 - 0.22 11.6 4.0 0.7 10.0 1.0 2.4 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain YqfD PF06898.11 OAP64608.1 - 0.33 9.7 6.8 0.55 9.0 6.8 1.3 1 0 0 1 1 1 0 Putative stage IV sporulation protein YqfD V_ATPase_I PF01496.19 OAP64608.1 - 4.3 5.1 6.3 4.9 5.0 6.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TF_Zn_Ribbon PF08271.12 OAP64608.1 - 5 6.7 6.2 3.6 7.2 1.6 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding Presenilin PF01080.17 OAP64608.1 - 5 5.8 7.4 6.7 5.4 7.4 1.3 1 0 0 1 1 1 0 Presenilin adh_short PF00106.25 OAP64609.1 - 3.6e-38 131.0 0.0 5e-38 130.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP64609.1 - 1.6e-27 96.6 0.0 2.7e-27 95.9 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP64609.1 - 6.7e-08 32.7 0.0 1.6e-07 31.4 0.0 1.6 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 OAP64609.1 - 6.6e-06 26.1 0.1 1.1e-05 25.4 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAP64609.1 - 0.00065 19.2 0.0 0.001 18.6 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 OAP64609.1 - 0.00066 18.9 0.1 0.001 18.3 0.1 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain DFP PF04127.15 OAP64609.1 - 0.017 14.9 0.0 0.028 14.2 0.0 1.2 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Polysacc_synt_C PF14667.6 OAP64611.1 - 0.041 13.9 0.2 0.07 13.2 0.2 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis C-terminal domain GST_N_2 PF13409.6 OAP64612.1 - 1.7e-14 53.9 0.0 5e-14 52.4 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 OAP64612.1 - 1.8e-13 50.7 0.0 4.9e-13 49.3 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 OAP64612.1 - 1.1e-11 44.9 0.1 5.6e-10 39.4 0.0 2.5 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 OAP64612.1 - 9.6e-06 25.7 0.0 1.7e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin GST_C_5 PF16865.5 OAP64612.1 - 0.041 14.5 0.0 0.13 12.9 0.0 2.0 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Thi4 PF01946.17 OAP64613.1 - 3.2e-115 383.3 0.0 3.9e-115 383.0 0.0 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 OAP64613.1 - 5e-08 32.9 1.2 4.1e-07 29.9 0.9 2.1 1 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAP64613.1 - 2.2e-06 27.8 0.3 7.6e-06 26.1 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 OAP64613.1 - 6.8e-06 25.4 0.2 1.3e-05 24.4 0.2 1.6 1 1 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 OAP64613.1 - 1.4e-05 24.5 0.1 2.4e-05 23.8 0.1 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAP64613.1 - 6.1e-05 22.3 1.4 0.0035 16.5 0.6 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.6 OAP64613.1 - 0.0012 18.8 1.5 0.0017 18.4 0.0 2.0 3 0 0 3 3 3 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 OAP64613.1 - 0.021 14.1 0.0 0.031 13.5 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.7 OAP64613.1 - 0.022 14.1 0.0 0.03 13.7 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 OAP64613.1 - 0.035 13.4 0.0 0.054 12.8 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAP64613.1 - 0.056 12.1 0.2 0.079 11.6 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein K_oxygenase PF13434.6 OAP64613.1 - 0.13 11.4 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.14 OAP64613.1 - 0.13 11.0 0.2 0.2 10.4 0.2 1.2 1 0 0 1 1 1 0 Tryptophan halogenase MFS_1 PF07690.16 OAP64614.1 - 1.5e-39 135.9 44.6 4e-39 134.5 44.6 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAP64614.1 - 1.1e-11 44.3 3.4 1.1e-11 44.3 3.4 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 OAP64614.1 - 0.0024 16.3 9.0 0.011 14.1 8.4 2.2 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Mpv17_PMP22 PF04117.12 OAP64616.1 - 4.9e-17 61.9 0.1 9e-17 61.1 0.1 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family FinO_N PF12602.8 OAP64616.1 - 0.1 13.0 0.6 14 6.1 0.1 2.3 2 0 0 2 2 2 0 Fertility inhibition protein N terminal ECH_1 PF00378.20 OAP64617.1 - 2.7e-51 174.3 0.0 3.8e-51 173.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAP64617.1 - 4.8e-23 82.2 0.0 1.9e-21 77.0 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 OAP64617.1 - 0.064 13.2 0.0 0.79 9.7 0.0 2.1 2 0 0 2 2 2 0 Peptidase family S49 PfkB PF00294.24 OAP64618.1 - 9.3e-38 130.2 0.1 1.3e-37 129.7 0.1 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Caleosin PF05042.13 OAP64619.1 - 1.3e-61 207.4 0.0 1.6e-61 207.1 0.0 1.1 1 0 0 1 1 1 1 Caleosin related protein EF-hand_1 PF00036.32 OAP64619.1 - 0.00092 18.6 1.3 0.15 11.6 0.1 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 OAP64619.1 - 0.0013 18.5 4.6 0.0031 17.3 0.2 2.9 3 0 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.6 OAP64619.1 - 0.007 16.8 0.0 0.13 12.8 0.0 2.6 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 OAP64619.1 - 0.026 14.0 2.4 0.17 11.4 0.2 2.4 2 0 0 2 2 2 0 EF hand CAP PF00188.26 OAP64620.1 - 7.4e-19 68.8 0.6 7.4e-19 68.8 0.6 1.6 2 0 0 2 2 2 1 Cysteine-rich secretory protein family Carn_acyltransf PF00755.20 OAP64621.1 - 5.5e-207 689.0 0.0 1.1e-206 688.0 0.0 1.4 1 1 0 1 1 1 1 Choline/Carnitine o-acyltransferase JmjC PF02373.22 OAP64622.1 - 4.2e-36 123.8 0.4 1.2e-35 122.4 0.4 1.9 1 0 0 1 1 1 1 JmjC domain, hydroxylase zf-HC5HC2H_2 PF13832.6 OAP64622.1 - 2.5e-19 69.4 7.6 5.2e-19 68.4 7.6 1.5 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 OAP64622.1 - 3.5e-17 62.4 7.2 3.5e-17 62.4 7.2 2.4 2 0 0 2 2 2 1 PHD-like zinc-binding domain JmjN PF02375.17 OAP64622.1 - 1.5e-09 37.6 0.1 4e-09 36.3 0.1 1.8 1 0 0 1 1 1 1 jmjN domain APH PF01636.23 OAP64623.1 - 5.7e-10 39.5 0.0 3.7e-09 36.9 0.0 2.1 2 1 0 2 2 2 1 Phosphotransferase enzyme family DUF1679 PF07914.11 OAP64623.1 - 0.02 13.8 0.0 0.66 8.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) TPR_7 PF13176.6 OAP64625.1 - 0.001 19.0 0.9 0.41 10.8 0.2 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 OAP64625.1 - 0.0022 17.8 1.8 0.23 11.4 0.3 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 OAP64625.1 - 0.0044 17.3 1.2 1.4 9.3 0.0 2.8 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 OAP64625.1 - 0.059 13.5 0.5 10 6.5 0.3 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 OAP64625.1 - 0.2 12.6 4.8 0.69 10.9 0.2 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 OAP64625.1 - 3.8 8.4 7.9 2.7 8.9 0.3 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat EthD PF07110.11 OAP64628.1 - 3.7e-08 34.4 0.2 1.2e-07 32.7 0.2 1.7 1 1 0 1 1 1 1 EthD domain Lentiviral_Tat PF02998.14 OAP64628.1 - 0.00044 20.2 0.2 0.00075 19.5 0.2 1.3 1 0 0 1 1 1 1 Lentiviral Tat protein HSP70 PF00012.20 OAP64629.1 - 2.8e-262 871.3 4.2 3.1e-262 871.1 4.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 OAP64629.1 - 1.1e-16 60.6 0.0 1.6e-15 56.8 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 OAP64629.1 - 0.0024 17.6 0.0 0.0054 16.5 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 OAP64629.1 - 0.0027 18.1 1.0 6.8 7.2 0.0 3.4 3 1 0 3 3 3 2 Cell division protein FtsA Hydantoinase_A PF01968.18 OAP64629.1 - 0.021 14.1 0.1 0.043 13.1 0.1 1.5 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase GRP PF07172.11 OAP64629.1 - 0.14 12.9 7.4 0.33 11.7 7.4 1.6 1 0 0 1 1 1 0 Glycine rich protein family Golgin_A5 PF09787.9 OAP64629.1 - 0.62 9.5 6.1 0.42 10.0 2.6 1.9 2 0 0 2 2 2 0 Golgin subfamily A member 5 CHZ PF09649.10 OAP64630.1 - 7e-11 41.4 2.8 7e-11 41.4 2.8 2.8 4 0 0 4 4 4 1 Histone chaperone domain CHZ MFAP1 PF06991.11 OAP64630.1 - 0.35 10.7 19.4 0.45 10.3 19.4 1.2 1 0 0 1 1 1 0 Microfibril-associated/Pre-mRNA processing VEFS-Box PF09733.9 OAP64631.1 - 5.5e-08 32.7 1.4 1.1e-07 31.7 1.4 1.5 1 0 0 1 1 1 1 VEFS-Box of polycomb protein DUF445 PF04286.12 OAP64631.1 - 0.17 11.7 2.5 0.13 12.1 0.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF445) Ssl1 PF04056.14 OAP64632.1 - 1.4e-51 175.1 0.0 1.9e-51 174.7 0.0 1.1 1 0 0 1 1 1 1 Ssl1-like VWA_2 PF13519.6 OAP64632.1 - 2.1e-17 63.7 0.0 3.9e-17 62.8 0.0 1.4 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 OAP64632.1 - 0.00022 21.5 0.0 0.00029 21.1 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain ERAP1_C PF11838.8 OAP64633.1 - 7.9e-84 281.9 0.0 1.6e-83 280.9 0.0 1.5 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 OAP64633.1 - 1.4e-83 279.8 4.0 2.5e-83 278.9 4.0 1.5 1 0 0 1 1 1 1 Peptidase family M1 domain Ras PF00071.22 OAP64633.1 - 4.1e-64 215.1 1.3 6.3e-64 214.5 0.5 1.8 2 0 0 2 2 2 1 Ras family Peptidase_M1_N PF17900.1 OAP64633.1 - 1.7e-41 142.4 0.1 9.4e-41 140.0 0.0 2.1 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain Roc PF08477.13 OAP64633.1 - 1.1e-34 119.3 0.1 2.9e-34 117.9 0.1 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAP64633.1 - 1.5e-15 57.1 0.1 6.8e-15 54.9 0.1 2.0 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OAP64633.1 - 0.00069 19.7 0.0 0.002 18.2 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OAP64633.1 - 0.0013 18.7 0.3 1.2 9.0 0.0 2.4 1 1 1 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 OAP64633.1 - 0.0021 17.7 0.1 0.0052 16.4 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OAP64633.1 - 0.0034 16.8 0.1 0.0065 15.9 0.1 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 OAP64633.1 - 0.0075 15.7 0.0 0.017 14.6 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit DUF2808 PF10989.8 OAP64633.1 - 0.011 15.7 0.0 0.027 14.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2808) AAA PF00004.29 OAP64633.1 - 0.069 13.6 0.1 3.6 8.0 0.0 2.9 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 OAP64633.1 - 0.086 12.6 0.0 0.27 11.0 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 OAP64633.1 - 0.14 12.5 0.0 0.33 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Saf_2TM PF18303.1 OAP64634.1 - 0.16 11.6 0.0 0.26 10.9 0.0 1.2 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain DUF4448 PF14610.6 OAP64634.1 - 0.18 11.6 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) SKG6 PF08693.10 OAP64634.1 - 0.92 9.0 4.1 1.9 8.0 4.1 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain F-box PF00646.33 OAP64635.1 - 0.0044 16.9 0.2 0.014 15.3 0.0 2.0 2 0 0 2 2 2 1 F-box domain PRANC PF09372.10 OAP64635.1 - 0.0079 16.5 0.0 0.034 14.5 0.0 2.0 2 0 0 2 2 2 1 PRANC domain F-box-like PF12937.7 OAP64635.1 - 0.09 12.7 0.2 0.2 11.6 0.2 1.7 1 0 0 1 1 1 0 F-box-like DUF1996 PF09362.10 OAP64637.1 - 7.2e-78 261.8 0.5 1e-77 261.3 0.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Asparaginase PF00710.20 OAP64638.1 - 7.1e-53 179.0 0.0 2.6e-52 177.1 0.0 1.9 1 1 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 OAP64638.1 - 1.8e-28 99.1 0.1 3.3e-28 98.2 0.1 1.5 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain Ank_2 PF12796.7 OAP64638.1 - 2.1e-12 47.4 3.0 4.1e-07 30.5 0.3 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAP64638.1 - 4.3e-07 30.3 0.2 3.8e-05 24.1 0.1 2.8 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAP64638.1 - 1.2e-05 25.3 2.5 0.093 13.3 0.1 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 OAP64638.1 - 2.2e-05 24.6 0.6 5.5e-05 23.4 0.6 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 OAP64638.1 - 0.00013 22.2 4.5 0.0041 17.5 0.9 3.1 2 0 0 2 2 2 1 Ankyrin repeat DMA PF03474.14 OAP64638.1 - 0.16 11.6 0.0 1.1 8.9 0.0 2.2 2 0 0 2 2 2 0 DMRTA motif NmrA PF05368.13 OAP64639.1 - 5.2e-73 245.4 0.0 6.3e-73 245.2 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAP64639.1 - 3.1e-07 30.4 0.0 5e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding His_Phos_1 PF00300.22 OAP64640.1 - 3.4e-29 101.9 0.0 1.3e-27 96.8 0.0 2.1 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) NUP PF06516.11 OAP64641.1 - 4.1e-135 450.0 0.3 4.8e-135 449.8 0.3 1.0 1 0 0 1 1 1 1 Purine nucleoside permease (NUP) UPF0029 PF01205.19 OAP64642.1 - 5.4e-34 116.7 0.3 1.5e-33 115.3 0.0 1.9 2 0 0 2 2 2 1 Uncharacterized protein family UPF0029 RWD PF05773.22 OAP64642.1 - 9.5e-08 32.3 0.0 3e-07 30.7 0.0 1.7 1 1 0 1 1 1 1 RWD domain MIP PF00230.20 OAP64643.1 - 5.1e-42 144.1 11.1 6.9e-42 143.7 11.1 1.1 1 0 0 1 1 1 1 Major intrinsic protein Cupin_2 PF07883.11 OAP64645.1 - 6.1e-09 35.5 0.0 1e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 OAP64645.1 - 0.035 13.8 0.1 0.064 13.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Clr5 PF14420.6 OAP64646.1 - 5.7e-19 68.1 0.7 1.5e-18 66.7 0.7 1.8 1 0 0 1 1 1 1 Clr5 domain TPR_12 PF13424.6 OAP64646.1 - 2.8e-12 46.8 3.7 4.1e-05 23.8 0.2 4.0 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.6 OAP64646.1 - 1.6e-06 27.8 1.8 0.00079 19.2 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF3856 PF12968.7 OAP64646.1 - 0.0019 18.3 0.3 0.23 11.6 0.2 2.6 2 0 0 2 2 2 1 Domain of Unknown Function (DUF3856) TPR_2 PF07719.17 OAP64646.1 - 0.026 14.6 0.4 8 6.8 0.1 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 OAP64646.1 - 0.029 14.9 0.1 0.64 10.6 0.1 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 OAP64646.1 - 0.043 14.5 4.0 2.9 8.6 0.0 3.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 OAP64646.1 - 0.78 9.7 3.0 2.5 8.1 0.1 3.0 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF1100 PF06500.11 OAP64647.1 - 5.3e-14 51.8 0.0 9.2e-14 51.0 0.0 1.3 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF1100) Peptidase_S15 PF02129.18 OAP64647.1 - 3.8e-09 36.5 0.0 6e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.20 OAP64647.1 - 1.3e-07 31.6 0.1 2.3e-06 27.5 0.1 2.1 1 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAP64647.1 - 1.1e-06 29.4 0.0 1.7e-06 28.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 OAP64647.1 - 4.4e-05 23.1 0.0 9.9e-05 21.9 0.0 1.8 1 1 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 OAP64647.1 - 0.00011 22.0 0.0 0.0005 19.8 0.0 2.0 1 1 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 OAP64647.1 - 0.00011 21.6 0.0 0.0002 20.7 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 BAAT_C PF08840.11 OAP64647.1 - 0.00053 20.0 0.0 0.0013 18.7 0.0 1.5 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_2 PF02230.16 OAP64647.1 - 0.0034 17.2 0.0 0.006 16.4 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_7 PF12715.7 OAP64647.1 - 0.0068 15.7 0.1 0.047 12.9 0.0 2.0 2 0 0 2 2 2 1 Abhydrolase family DLH PF01738.18 OAP64647.1 - 0.048 13.2 0.0 0.21 11.1 0.0 1.9 1 1 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 OAP64647.1 - 0.065 13.1 0.0 0.2 11.5 0.0 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold LIDHydrolase PF10230.9 OAP64647.1 - 0.16 11.5 0.0 0.26 10.8 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Esterase_phd PF10503.9 OAP64647.1 - 0.24 10.9 0.0 0.52 9.7 0.0 1.5 2 0 0 2 2 2 0 Esterase PHB depolymerase F-box PF00646.33 OAP64648.1 - 4.6e-05 23.2 0.7 0.00013 21.8 0.7 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 OAP64648.1 - 0.00034 20.4 0.8 0.00086 19.2 0.8 1.7 1 0 0 1 1 1 1 F-box-like p450 PF00067.22 OAP64649.1 - 5e-51 173.9 0.0 1.3e-50 172.5 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 CN_hydrolase PF00795.22 OAP64650.1 - 6.6e-39 133.8 0.0 1.1e-38 133.2 0.0 1.3 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase Asp_Glu_race PF01177.22 OAP64651.1 - 5.3e-11 42.8 0.1 7.4e-11 42.3 0.1 1.2 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase Amdase PF17645.1 OAP64651.1 - 0.001 18.7 0.3 0.0018 18.0 0.3 1.4 1 0 0 1 1 1 1 Arylmalonate decarboxylase Catalase PF00199.19 OAP64652.1 - 1.2e-27 97.0 0.0 1.5e-27 96.7 0.0 1.0 1 0 0 1 1 1 1 Catalase Ank_4 PF13637.6 OAP64654.1 - 0.0012 19.4 0.1 0.021 15.4 0.0 2.6 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Amidohydro_1 PF01979.20 OAP64655.1 - 1e-27 97.4 0.0 1.3e-27 97.0 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 OAP64655.1 - 2.7e-19 70.0 0.3 6e-09 35.9 0.0 2.6 3 0 0 3 3 3 2 Amidohydrolase family Urease_alpha PF00449.20 OAP64655.1 - 0.05 13.9 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 Urease alpha-subunit, N-terminal domain Transp_cyt_pur PF02133.15 OAP64656.1 - 1.5e-89 300.8 41.4 2e-89 300.4 41.4 1.2 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin ADH_N PF08240.12 OAP64657.1 - 3e-26 91.4 4.1 3e-26 91.4 4.1 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_N_assoc PF13823.6 OAP64657.1 - 0.00026 20.9 0.4 0.00026 20.9 0.4 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-associated Neuroparsin PF07327.11 OAP64657.1 - 0.012 16.0 1.7 0.031 14.7 1.7 1.6 1 0 0 1 1 1 0 Neuroparsin HydF_tetramer PF18133.1 OAP64657.1 - 0.028 14.2 0.4 0.07 12.9 0.4 1.6 1 0 0 1 1 1 0 Hydrogen maturase F tetramerization domain WD40 PF00400.32 OAP64658.1 - 0.0011 19.7 0.3 0.0011 19.7 0.3 3.0 2 1 0 2 2 2 1 WD domain, G-beta repeat WW PF00397.26 OAP64659.1 - 1.8e-10 40.7 4.2 3.7e-10 39.7 4.2 1.6 1 0 0 1 1 1 1 WW domain Aminotran_3 PF00202.21 OAP64660.1 - 4.1e-87 292.5 0.0 5.1e-87 292.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Zn_clus PF00172.18 OAP64661.1 - 6.9e-05 22.9 8.0 0.00016 21.7 8.0 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAP64661.1 - 0.00031 19.9 0.1 0.0018 17.3 0.1 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF390 PF04094.14 OAP64661.1 - 0.65 8.2 8.2 0.94 7.7 8.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF390) MSA-2c PF12238.8 OAP64661.1 - 7.5 6.5 9.6 15 5.5 9.6 1.4 1 0 0 1 1 1 0 Merozoite surface antigen 2c Beta-lactamase PF00144.24 OAP64662.1 - 1.3e-42 146.2 0.5 2.8e-42 145.1 0.5 1.5 1 1 0 1 1 1 1 Beta-lactamase Beta-lactamase2 PF13354.6 OAP64662.1 - 0.0053 16.4 0.0 0.18 11.4 0.0 2.1 2 0 0 2 2 2 1 Beta-lactamase enzyme family Glutaminase PF04960.15 OAP64662.1 - 0.043 13.0 0.0 0.27 10.4 0.0 1.9 2 0 0 2 2 2 0 Glutaminase DUF2012 PF09430.10 OAP64663.1 - 9.2e-26 90.4 0.0 1.2e-25 90.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) EAV_GS PF01309.18 OAP64663.1 - 0.041 13.5 0.0 0.063 12.9 0.0 1.3 1 0 0 1 1 1 0 Equine arteritis virus small envelope glycoprotein DUF1749 PF08538.10 OAP64665.1 - 4e-66 223.1 0.0 4.8e-66 222.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.7 OAP64665.1 - 7.5e-08 33.2 1.2 1e-07 32.8 1.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAP64665.1 - 7.2e-05 22.2 0.0 0.0019 17.5 0.0 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 OAP64665.1 - 0.0048 16.8 0.1 0.017 15.0 0.0 1.8 2 0 0 2 2 2 1 Serine hydrolase LSDAT_euk PF18139.1 OAP64665.1 - 0.19 11.1 0.0 0.32 10.4 0.0 1.2 1 0 0 1 1 1 0 SLOG in TRPM Cutinase PF01083.22 OAP64665.1 - 0.21 11.6 0.0 0.33 10.9 0.0 1.3 1 0 0 1 1 1 0 Cutinase MFS_1 PF07690.16 OAP64666.1 - 7.1e-42 143.6 44.5 7.1e-42 143.6 44.5 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAP64666.1 - 9.2e-07 28.1 14.0 9.2e-07 28.1 14.0 2.8 2 1 1 3 3 3 1 Sugar (and other) transporter PDDEXK_5 PF11645.8 OAP64666.1 - 0.095 12.7 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 PD-(D/E)XK endonuclease TrkH PF02386.16 OAP64668.1 - 9.3e-152 506.0 9.2 1.2e-150 502.3 4.2 2.1 2 0 0 2 2 2 2 Cation transport protein Glyco_hydro_76 PF03663.14 OAP64669.1 - 3e-145 484.4 22.6 3.4e-145 484.2 22.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 OAP64669.1 - 0.026 13.6 9.6 1.5 7.8 9.6 2.8 1 1 1 2 2 2 0 Glycosyl Hydrolase Family 88 DUF4048 PF13257.6 OAP64670.1 - 4.6e-37 128.3 18.8 2.2e-35 122.7 14.7 2.8 2 1 0 2 2 2 1 Domain of unknown function (DUF4048) Bap31_Bap29_C PF18035.1 OAP64670.1 - 0.0083 16.1 1.6 0.02 14.9 1.6 1.6 1 0 0 1 1 1 1 Bap31/Bap29 cytoplasmic coiled-coil domain Pkinase PF00069.25 OAP64671.1 - 4e-65 219.8 0.0 6.6e-65 219.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP64671.1 - 1.3e-45 155.8 0.0 2.4e-45 154.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAP64671.1 - 7.8e-05 21.6 0.0 7.8e-05 21.6 0.0 2.8 3 0 0 3 3 3 1 Fungal protein kinase Kinase-like PF14531.6 OAP64671.1 - 0.0081 15.5 0.0 0.025 13.9 0.0 1.8 2 0 0 2 2 2 1 Kinase-like MFS_1 PF07690.16 OAP64672.1 - 3.2e-27 95.4 22.1 3.2e-27 95.4 22.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily NADHdh-2_N PF12155.8 OAP64672.1 - 0.1 13.0 0.1 0.28 11.6 0.1 1.7 1 0 0 1 1 1 0 NADH dehydrogenase subunit 2 N-terminal Fungal_trans_2 PF11951.8 OAP64673.1 - 2e-57 194.7 0.9 2.3e-57 194.6 0.9 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain BLM10_mid PF16507.5 OAP64673.1 - 0.095 11.3 0.0 0.14 10.7 0.0 1.2 1 0 0 1 1 1 0 Proteasome-substrate-size regulator, mid region DAO PF01266.24 OAP64674.1 - 7.3e-36 124.5 0.1 8.9e-36 124.2 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase ThiF PF00899.21 OAP64674.1 - 4.6e-06 26.2 0.1 3e-05 23.5 0.0 2.1 3 0 0 3 3 3 1 ThiF family Pyr_redox_2 PF07992.14 OAP64674.1 - 4.3e-05 22.9 0.0 0.033 13.4 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAP64674.1 - 0.00017 21.7 0.0 0.00064 19.9 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 OAP64674.1 - 0.00068 18.8 0.0 0.26 10.3 0.0 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_2 PF00890.24 OAP64674.1 - 0.0013 17.9 0.0 0.24 10.5 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_7 PF13241.6 OAP64674.1 - 0.0019 18.6 0.0 0.0043 17.5 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 OAP64674.1 - 0.0027 17.8 0.0 0.0045 17.1 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 OAP64674.1 - 0.0038 17.8 0.0 0.038 14.6 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 OAP64674.1 - 0.016 14.5 0.0 0.028 13.7 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.6 OAP64674.1 - 0.03 14.3 0.0 0.59 10.1 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding 3HCDH_N PF02737.18 OAP64674.1 - 0.036 13.9 0.0 1.3 8.9 0.0 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain EntA_Immun PF08951.10 OAP64674.1 - 0.13 12.6 0.0 0.22 11.9 0.0 1.4 1 0 0 1 1 1 0 Enterocin A Immunity TadE PF07811.12 OAP64674.1 - 0.18 12.1 0.2 0.62 10.4 0.1 1.9 2 0 0 2 2 2 0 TadE-like protein TRI12 PF06609.13 OAP64675.1 - 1.8e-32 112.6 30.6 2.2e-32 112.3 30.6 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAP64675.1 - 2.1e-16 59.8 64.7 1e-15 57.5 57.0 3.0 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAP64675.1 - 1.1e-09 37.8 15.4 1.1e-09 37.8 15.4 3.0 2 1 0 2 2 2 2 Sugar (and other) transporter ADH_N PF08240.12 OAP64677.1 - 8.9e-28 96.4 0.2 1.6e-27 95.5 0.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAP64677.1 - 9.7e-20 70.9 0.0 1.7e-19 70.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 OAP64677.1 - 0.00012 21.6 0.5 0.00045 19.8 0.5 1.8 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus DZR PF12773.7 OAP64677.1 - 0.042 13.9 0.3 0.042 13.9 0.3 1.6 2 0 0 2 2 2 0 Double zinc ribbon DNA_ligase_A_M PF01068.21 OAP64678.1 - 1.5e-25 90.0 0.0 4.8e-25 88.4 0.0 1.8 2 0 0 2 2 2 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 OAP64678.1 - 1.3e-15 58.1 0.0 3.5e-15 56.7 0.0 1.7 2 0 0 2 2 2 1 DNA ligase N terminus AA_permease PF00324.21 OAP64679.1 - 2.2e-122 409.1 33.3 2.7e-122 408.8 33.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAP64679.1 - 8e-37 127.1 36.5 1e-36 126.7 36.5 1.1 1 0 0 1 1 1 1 Amino acid permease Scramblase PF03803.15 OAP64680.1 - 9e-51 172.3 0.0 1.7e-26 92.9 0.0 2.9 1 1 1 2 2 2 2 Scramblase Kelch_5 PF13854.6 OAP64681.1 - 9.9e-10 38.2 4.9 1.6e-06 27.9 0.1 4.5 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.6 OAP64681.1 - 9.4e-05 22.3 8.4 3 7.9 0.0 5.4 4 1 1 5 5 5 3 Galactose oxidase, central domain Kelch_3 PF13415.6 OAP64681.1 - 0.00083 19.6 12.4 0.066 13.5 0.2 5.4 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_6 PF13964.6 OAP64681.1 - 0.0051 17.1 3.0 4 7.9 0.0 4.8 4 1 0 4 4 4 1 Kelch motif Kelch_2 PF07646.15 OAP64681.1 - 0.055 13.5 1.7 2.3 8.4 0.0 3.7 4 0 0 4 4 4 0 Kelch motif Herpes_gE PF02480.16 OAP64681.1 - 0.063 12.0 0.0 0.088 11.5 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF4381 PF14316.6 OAP64681.1 - 0.12 12.6 0.0 0.25 11.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Kelch_1 PF01344.25 OAP64681.1 - 2.3 7.9 10.2 5.4 6.7 0.0 4.8 5 0 0 5 5 5 0 Kelch motif p450 PF00067.22 OAP64682.1 - 1.2e-42 146.2 0.2 4.6e-28 98.2 0.0 2.4 2 1 0 2 2 2 2 Cytochrome P450 Fungal_trans PF04082.18 OAP64683.1 - 1.2e-08 34.4 0.9 2.8e-08 33.1 0.9 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain AnmK PF03702.14 OAP64684.1 - 4.4e-85 286.0 0.0 5.1e-85 285.8 0.0 1.0 1 0 0 1 1 1 1 Anhydro-N-acetylmuramic acid kinase adh_short_C2 PF13561.6 OAP64685.1 - 3.2e-53 180.7 0.6 5.1e-53 180.0 0.6 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP64685.1 - 4.2e-43 147.1 2.3 5.7e-43 146.7 2.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAP64685.1 - 2.6e-12 47.0 0.5 1.4e-11 44.6 0.1 2.0 2 0 0 2 2 2 1 KR domain Sugar_tr PF00083.24 OAP64686.1 - 1.1e-79 268.4 22.9 1.3e-79 268.2 22.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP64686.1 - 2.7e-25 89.1 41.3 4.5e-18 65.3 13.3 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily Gly-zipper_Omp PF13488.6 OAP64686.1 - 0.021 14.8 2.4 0.021 14.8 2.4 2.5 2 0 0 2 2 2 0 Glycine zipper Transgly_assoc PF04226.13 OAP64686.1 - 0.035 14.4 3.3 0.035 14.4 3.3 2.9 3 0 0 3 3 3 0 Transglycosylase associated protein Gly-zipper_YMGG PF13441.6 OAP64686.1 - 0.23 11.2 4.7 0.79 9.5 4.7 1.9 1 0 0 1 1 1 0 YMGG-like Gly-zipper Rick_17kDa_Anti PF05433.15 OAP64686.1 - 0.95 9.4 8.6 0.063 13.1 2.6 2.2 2 0 0 2 2 2 0 Glycine zipper 2TM domain DUF3413 PF11893.8 OAP64686.1 - 10 5.2 13.5 5.5 6.1 8.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3413) GFO_IDH_MocA PF01408.22 OAP64687.1 - 9.1e-12 45.9 0.0 1.5e-11 45.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold TPR_12 PF13424.6 OAP64688.1 - 1.3e-40 137.5 8.5 3.4e-11 43.3 0.1 5.7 2 1 1 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.6 OAP64688.1 - 5.8e-28 96.0 1.2 1.2e-07 31.3 0.0 6.6 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_1 PF00515.28 OAP64688.1 - 1.7e-17 62.4 9.6 0.01 15.7 0.6 8.5 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_8 PF13181.6 OAP64688.1 - 7e-13 47.7 11.0 0.086 13.1 0.1 7.0 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 OAP64688.1 - 9.5e-13 47.2 0.8 0.077 13.1 0.0 6.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 OAP64688.1 - 1.2e-11 43.8 13.6 0.18 12.0 0.3 7.5 8 0 0 8 8 7 5 Tetratricopeptide repeat HET PF06985.11 OAP64688.1 - 1e-09 38.9 0.1 2.3e-09 37.8 0.1 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) TPR_MalT PF17874.1 OAP64688.1 - 1.2e-09 38.0 5.6 2.1e-07 30.6 0.1 3.2 1 1 1 3 3 3 2 MalT-like TPR region TPR_19 PF14559.6 OAP64688.1 - 3.7e-06 27.3 0.1 0.0072 16.8 0.0 4.3 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 OAP64688.1 - 1.3e-05 25.8 0.4 0.71 10.6 0.0 5.6 6 1 1 7 7 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 OAP64688.1 - 7.4e-05 23.2 0.0 22 6.2 0.0 5.6 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF2225 PF09986.9 OAP64688.1 - 0.00071 19.4 4.0 0.2 11.3 0.3 3.2 3 0 0 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2225) TPR_17 PF13431.6 OAP64688.1 - 0.03 14.7 0.1 85 3.9 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 OAP64688.1 - 0.087 13.5 2.6 9.2 7.1 0.1 4.5 6 0 0 6 6 3 0 Tetratricopeptide repeat NB-ARC PF00931.22 OAP64688.1 - 0.11 11.7 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain PPR PF01535.20 OAP64688.1 - 0.18 12.1 1.6 31 5.1 0.0 4.6 5 0 0 5 5 5 0 PPR repeat TPR_11 PF13414.6 OAP64688.1 - 0.21 11.3 13.7 78 3.1 0.0 6.5 6 0 0 6 6 6 0 TPR repeat MIT PF04212.18 OAP64688.1 - 0.92 9.6 10.5 18 5.5 0.6 5.4 6 1 1 7 7 6 0 MIT (microtubule interacting and transport) domain ABC_tran PF00005.27 OAP64689.1 - 1e-49 168.6 0.0 5.6e-26 91.7 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 OAP64689.1 - 1.3e-22 80.4 50.0 1.3e-14 54.1 26.3 2.6 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 OAP64689.1 - 3e-22 79.8 1.0 0.00013 21.9 0.0 4.4 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OAP64689.1 - 9.6e-10 38.3 0.6 8.2e-06 25.4 0.1 3.7 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 OAP64689.1 - 6.4e-09 35.4 1.2 0.00013 21.6 0.4 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 OAP64689.1 - 6e-08 33.4 0.6 0.0037 17.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_27 PF13514.6 OAP64689.1 - 2e-05 24.3 0.2 0.17 11.4 0.1 2.4 2 0 0 2 2 2 2 AAA domain DUF4162 PF13732.6 OAP64689.1 - 4.9e-05 24.0 0.0 0.018 15.8 0.0 3.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4162) RsgA_GTPase PF03193.16 OAP64689.1 - 0.00014 21.8 0.3 0.35 10.7 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 OAP64689.1 - 0.00022 21.7 0.1 0.46 10.8 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_15 PF13175.6 OAP64689.1 - 0.00033 20.5 0.0 0.098 12.3 0.0 3.0 3 0 0 3 3 3 1 AAA ATPase domain AAA_30 PF13604.6 OAP64689.1 - 0.00041 20.1 0.4 1.3 8.7 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_28 PF13521.6 OAP64689.1 - 0.013 15.8 0.2 0.68 10.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 OAP64689.1 - 0.02 15.1 0.0 3.4 7.9 0.0 3.0 3 0 0 3 3 2 0 AAA domain SRP54 PF00448.22 OAP64689.1 - 0.035 13.7 0.7 8.6 5.9 0.2 2.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain RNA_helicase PF00910.22 OAP64689.1 - 0.045 14.2 0.0 3.4 8.1 0.0 2.6 2 0 0 2 2 2 0 RNA helicase Zeta_toxin PF06414.12 OAP64689.1 - 0.059 12.6 0.1 9 5.5 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin MukB PF04310.12 OAP64689.1 - 0.067 13.0 0.2 20 4.9 0.0 2.8 3 0 0 3 3 3 0 MukB N-terminal Rad17 PF03215.15 OAP64689.1 - 0.089 12.7 0.0 7.2 6.5 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_18 PF13238.6 OAP64689.1 - 0.14 12.7 0.7 13 6.4 0.0 3.1 3 0 0 3 3 2 0 AAA domain EPV_E5 PF08135.11 OAP64689.1 - 0.55 10.6 3.6 2 8.8 3.6 1.9 1 0 0 1 1 1 0 Major transforming protein E5 family SbcCD_C PF13558.6 OAP64689.1 - 3 8.2 9.3 6.1 7.2 0.0 4.5 4 2 0 4 4 3 0 Putative exonuclease SbcCD, C subunit ABC2_membrane PF01061.24 OAP64690.1 - 7.5e-77 257.5 63.9 5.8e-40 137.0 16.9 2.9 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 OAP64690.1 - 5.2e-34 117.7 0.0 1.4e-16 61.2 0.0 2.8 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 OAP64690.1 - 3.7e-23 81.2 10.2 3.2e-22 78.2 0.0 3.4 4 0 0 4 4 2 2 CDR ABC transporter ABC_trans_N PF14510.6 OAP64690.1 - 3e-14 53.4 1.2 1e-13 51.7 0.1 2.5 2 0 0 2 2 2 1 ABC-transporter N-terminal AAA_21 PF13304.6 OAP64690.1 - 2.5e-06 27.5 0.4 0.19 11.5 0.0 3.3 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 OAP64690.1 - 2.6e-05 24.7 0.2 0.013 15.9 0.1 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 OAP64690.1 - 8.8e-05 22.7 2.8 0.069 13.3 0.0 3.1 3 0 0 3 3 2 2 AAA domain ABC2_membrane_3 PF12698.7 OAP64690.1 - 0.00012 21.4 21.5 0.00012 21.4 21.5 2.5 2 0 0 2 2 2 1 ABC-2 family transporter protein AAA_29 PF13555.6 OAP64690.1 - 0.00027 20.6 0.2 0.013 15.2 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 OAP64690.1 - 0.00038 20.4 0.1 0.0015 18.5 0.0 2.0 2 0 0 2 2 2 1 RsgA GTPase AAA_18 PF13238.6 OAP64690.1 - 0.0016 19.0 7.2 0.072 13.6 0.0 3.9 4 0 0 4 4 3 1 AAA domain AAA_25 PF13481.6 OAP64690.1 - 0.002 17.8 0.2 0.037 13.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 OAP64690.1 - 0.0027 17.2 0.0 0.29 10.5 0.0 3.0 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_28 PF13521.6 OAP64690.1 - 0.0045 17.3 0.4 0.23 11.7 0.1 2.8 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 OAP64690.1 - 0.0099 15.6 0.4 1.3 8.7 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 OAP64690.1 - 0.011 16.0 0.6 0.54 10.5 0.1 2.8 2 1 0 2 2 2 0 AAA domain NACHT PF05729.12 OAP64690.1 - 0.031 14.2 0.3 4.8 7.1 0.2 2.5 2 0 0 2 2 2 0 NACHT domain cobW PF02492.19 OAP64690.1 - 0.058 13.0 1.9 0.51 9.9 0.4 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Amino_oxidase PF01593.24 OAP64690.1 - 0.13 11.5 0.0 0.4 9.9 0.0 1.8 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase AAA_17 PF13207.6 OAP64690.1 - 0.14 12.6 6.4 0.41 11.1 0.1 3.0 3 0 0 3 3 2 0 AAA domain PduV-EutP PF10662.9 OAP64690.1 - 0.24 11.1 0.4 11 5.7 0.1 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_23 PF13476.6 OAP64690.1 - 0.36 11.3 8.0 0.46 11.0 0.0 3.5 4 0 0 4 4 3 0 AAA domain BTB PF00651.31 OAP64691.1 - 3e-06 27.4 0.0 5.4e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain DsrC PF04358.13 OAP64691.1 - 0.083 13.4 0.2 0.33 11.5 0.1 1.9 1 1 1 2 2 2 0 DsrC like protein Macoilin PF09726.9 OAP64691.1 - 2.9 6.3 11.3 4.2 5.8 11.3 1.2 1 0 0 1 1 1 0 Macoilin family GREB1 PF15782.5 OAP64691.1 - 4.3 4.3 9.5 5.9 3.9 9.5 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer UCH PF00443.29 OAP64692.1 - 2.4e-45 155.0 0.0 4.5e-45 154.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OAP64692.1 - 1.5e-10 41.2 0.0 3.5e-05 23.5 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase zf-C3HC4 PF00097.25 OAP64693.1 - 3.8e-07 29.9 7.4 7.7e-07 28.9 7.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OAP64693.1 - 2.3e-06 27.4 6.1 5e-06 26.3 6.1 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAP64693.1 - 2.3e-06 27.5 3.4 2.3e-06 27.5 3.4 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OAP64693.1 - 5.1e-06 26.2 6.7 1.6e-05 24.7 2.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAP64693.1 - 9.2e-06 25.5 3.5 2.3e-05 24.3 3.6 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 OAP64693.1 - 1.1e-05 25.7 7.9 2.4e-05 24.6 7.9 1.6 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 OAP64693.1 - 4e-05 23.7 5.9 0.00023 21.2 6.2 2.0 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 OAP64693.1 - 0.0041 17.0 7.4 0.024 14.5 7.5 2.2 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 OAP64693.1 - 1.3 9.4 6.0 4 7.8 6.0 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_10 PF16685.5 OAP64693.1 - 3.6 7.8 5.4 0.92 9.7 2.2 1.6 2 0 0 2 2 2 0 zinc RING finger of MSL2 zf-ribbon_3 PF13248.6 OAP64693.1 - 4.1 6.9 5.1 9.7 5.8 0.9 2.4 2 0 0 2 2 2 0 zinc-ribbon domain DJ-1_PfpI PF01965.24 OAP64694.1 - 4.2e-13 49.4 0.2 1.7e-12 47.4 0.2 1.9 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 OAP64694.1 - 0.00037 20.2 0.0 0.00065 19.4 0.0 1.4 1 0 0 1 1 1 1 ThiJ/PfpI family-like adh_short PF00106.25 OAP64695.1 - 9e-13 48.1 0.0 1.2e-12 47.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP64695.1 - 6.9e-08 32.3 0.0 8.3e-08 32.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP64695.1 - 0.017 15.0 0.0 0.03 14.3 0.0 1.3 1 0 0 1 1 1 0 KR domain 3HCDH_N PF02737.18 OAP64695.1 - 0.02 14.7 0.0 0.029 14.3 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TPR_17 PF13431.6 OAP64696.1 - 0.12 12.8 0.0 0.37 11.3 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Frataxin_Cyay PF01491.16 OAP64698.1 - 9e-37 125.5 0.0 1.3e-36 125.0 0.0 1.2 1 0 0 1 1 1 1 Frataxin-like domain Methyltransf_2 PF00891.18 OAP64699.1 - 3.5e-23 82.0 0.0 5.2e-23 81.5 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 OAP64699.1 - 4.3e-05 23.4 0.0 0.00022 21.1 0.0 2.0 2 0 0 2 2 2 1 Dimerisation domain Dimerisation PF08100.11 OAP64699.1 - 0.001 19.0 0.0 0.0098 15.9 0.0 2.5 2 0 0 2 2 2 1 Dimerisation domain NinB PF05772.12 OAP64699.1 - 0.11 12.4 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 NinB protein Rrf2 PF02082.20 OAP64699.1 - 0.17 12.3 0.0 0.69 10.3 0.0 2.1 1 1 0 1 1 1 0 Transcriptional regulator Fungal_trans PF04082.18 OAP64700.1 - 7.2e-06 25.2 0.2 1.1e-05 24.6 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP64701.1 - 4.8e-05 23.4 9.0 7.7e-05 22.7 9.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SR-25 PF10500.9 OAP64701.1 - 0.14 11.7 14.2 0.21 11.2 14.2 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Dehydrin PF00257.19 OAP64701.1 - 1.5 9.3 8.4 2.9 8.4 8.4 1.4 1 0 0 1 1 1 0 Dehydrin RAP1 PF07218.11 OAP64701.1 - 9.9 4.3 6.0 12 4.1 6.0 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) MFS_1 PF07690.16 OAP64702.1 - 7.2e-09 35.0 37.9 6.9e-05 21.9 28.1 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.16 OAP64702.1 - 1e-08 35.1 6.3 1e-08 35.1 6.3 2.6 2 1 0 2 2 2 1 Ion channel regulatory protein UNC-93 Peptidase_M20 PF01546.28 OAP64703.1 - 3.9e-27 95.3 0.1 6.4e-27 94.6 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 OAP64703.1 - 8.4e-06 25.7 0.0 1.8e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 OAP64703.1 - 0.043 13.5 0.2 0.086 12.5 0.0 1.6 2 0 0 2 2 2 0 Peptidase family M28 Amidase_2 PF01510.25 OAP64703.1 - 0.063 13.7 0.0 0.25 11.8 0.0 2.1 2 1 0 2 2 2 0 N-acetylmuramoyl-L-alanine amidase AAA_35 PF14516.6 OAP64703.1 - 0.19 10.6 0.0 0.28 10.0 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain Methyltransf_25 PF13649.6 OAP64704.1 - 7.9e-18 65.0 0.1 1.4e-17 64.2 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAP64704.1 - 3.4e-17 62.9 0.1 6.2e-17 62.0 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAP64704.1 - 6.8e-15 55.2 0.0 9.9e-15 54.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAP64704.1 - 4.1e-10 40.3 0.0 7.7e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAP64704.1 - 7.3e-09 35.7 0.0 8.8e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAP64704.1 - 1.2e-07 31.4 0.0 1.9e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 OAP64704.1 - 3.1e-07 30.1 0.0 4e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain MetW PF07021.12 OAP64704.1 - 4.6e-06 26.4 0.2 6.5e-06 25.9 0.2 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_16 PF10294.9 OAP64704.1 - 0.00066 19.5 0.1 0.00094 19.0 0.1 1.2 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 OAP64704.1 - 0.0017 17.8 0.0 0.0025 17.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_8 PF05148.15 OAP64704.1 - 0.0028 17.5 0.0 0.0036 17.2 0.0 1.3 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_32 PF13679.6 OAP64704.1 - 0.012 15.6 0.1 0.019 15.0 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.20 OAP64704.1 - 0.013 14.9 0.0 0.019 14.3 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.7 OAP64704.1 - 0.037 14.0 0.0 0.061 13.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain ABC_membrane PF00664.23 OAP64705.1 - 3.7e-102 341.6 37.1 2.2e-51 175.1 15.8 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 OAP64705.1 - 2.1e-67 225.8 0.1 2.7e-33 115.4 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 OAP64705.1 - 1.1e-14 54.4 0.0 1.2e-05 24.9 0.0 4.5 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 OAP64705.1 - 7.8e-08 32.4 0.1 0.0083 16.0 0.0 3.5 3 0 0 3 3 3 2 RsgA GTPase AAA_16 PF13191.6 OAP64705.1 - 4.7e-07 30.3 3.4 0.0041 17.5 0.2 3.1 3 1 0 3 3 2 2 AAA ATPase domain AAA_22 PF13401.6 OAP64705.1 - 1.2e-06 28.8 0.8 0.018 15.3 0.1 3.6 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.6 OAP64705.1 - 3e-06 26.9 2.4 0.068 12.9 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.6 OAP64705.1 - 3.5e-06 27.0 0.0 0.022 14.5 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_30 PF13604.6 OAP64705.1 - 2e-05 24.4 2.1 0.092 12.5 0.2 3.7 3 1 0 3 3 3 2 AAA domain AAA_21 PF13304.6 OAP64705.1 - 2.5e-05 24.2 0.2 0.45 10.3 0.0 3.6 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC_ATPase PF09818.9 OAP64705.1 - 0.00088 18.2 6.9 0.1 11.4 0.1 3.8 4 0 0 4 4 4 1 Predicted ATPase of the ABC class AAA_25 PF13481.6 OAP64705.1 - 0.0013 18.3 0.0 0.49 10.0 0.0 2.9 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 OAP64705.1 - 0.0014 18.0 0.0 0.34 10.2 0.0 2.8 2 0 0 2 2 2 1 Zeta toxin PRK PF00485.18 OAP64705.1 - 0.002 17.9 0.0 1.1 9.0 0.0 2.7 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 OAP64705.1 - 0.0021 18.6 0.0 0.58 10.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 OAP64705.1 - 0.0049 17.4 0.4 1.3 9.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 OAP64705.1 - 0.0051 16.9 0.4 1.5 8.8 0.2 2.5 2 0 0 2 2 2 1 Helicase HerA, central domain G-alpha PF00503.20 OAP64705.1 - 0.0065 15.7 0.0 0.62 9.2 0.0 2.2 2 0 0 2 2 2 1 G-protein alpha subunit Tnp_DNA_bind PF14706.6 OAP64705.1 - 0.0079 16.0 0.0 0.022 14.6 0.0 1.8 1 0 0 1 1 1 1 Transposase DNA-binding AAA_33 PF13671.6 OAP64705.1 - 0.0081 16.3 0.2 5.5 7.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 OAP64705.1 - 0.0088 15.3 0.1 4.5 6.4 0.0 2.6 3 0 0 3 3 2 1 NB-ARC domain SbcCD_C PF13558.6 OAP64705.1 - 0.0098 16.1 2.1 2.4 8.5 0.3 3.7 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.14 OAP64705.1 - 0.016 15.2 0.1 12 5.9 0.0 3.4 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 OAP64705.1 - 0.017 15.3 0.2 0.65 10.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 OAP64705.1 - 0.019 15.0 2.2 3.8 7.6 0.0 3.2 4 0 0 4 4 3 0 50S ribosome-binding GTPase RNA_helicase PF00910.22 OAP64705.1 - 0.027 14.8 0.2 13 6.2 0.1 3.0 3 0 0 3 3 2 0 RNA helicase NACHT PF05729.12 OAP64705.1 - 0.047 13.6 0.7 4.8 7.1 0.3 3.1 3 0 0 3 3 3 0 NACHT domain AAA_24 PF13479.6 OAP64705.1 - 0.063 13.0 0.2 6.7 6.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 OAP64705.1 - 0.2 11.6 0.0 20 5.0 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain ATP_bind_1 PF03029.17 OAP64705.1 - 0.22 11.3 1.4 14 5.4 0.1 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_19 PF13245.6 OAP64705.1 - 0.35 11.2 1.5 1.7 9.0 0.0 2.7 3 0 0 3 3 2 0 AAA domain Dynamin_N PF00350.23 OAP64705.1 - 3.1 7.8 7.4 48 4.0 0.3 4.0 5 0 0 5 5 3 0 Dynamin family Zn_clus PF00172.18 OAP64706.1 - 1e-08 35.2 9.8 1.9e-08 34.3 9.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 OAP64706.1 - 0.0025 16.7 0.7 0.0038 16.1 0.7 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain TauD PF02668.16 OAP64707.1 - 3.4e-19 69.7 4.7 9.8e-17 61.6 4.7 2.6 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.16 OAP64709.1 - 1.9e-29 102.7 14.4 1.9e-29 102.7 14.4 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 OAP64709.1 - 0.085 12.1 8.6 0.026 13.8 4.0 2.3 3 0 0 3 3 3 0 Uncharacterised MFS-type transporter YbfB Aa_trans PF01490.18 OAP64711.1 - 3e-42 144.8 34.1 3.5e-42 144.6 34.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 OAP64711.1 - 0.00061 18.9 17.1 0.00061 18.9 17.1 2.0 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family CstA PF02554.14 OAP64711.1 - 0.0025 16.8 19.7 0.0025 16.8 19.7 1.6 1 1 1 2 2 2 1 Carbon starvation protein CstA Sec6 PF06046.13 OAP64712.1 - 2.5e-151 504.9 2.4 2.5e-151 504.9 2.4 1.6 2 0 0 2 2 2 1 Exocyst complex component Sec6 Vps53_N PF04100.12 OAP64712.1 - 0.0049 15.9 4.8 0.02 13.9 0.6 2.6 2 1 0 2 2 2 1 Vps53-like, N-terminal LOH1CR12 PF10158.9 OAP64712.1 - 0.091 12.8 0.6 0.76 9.8 0.1 2.6 2 0 0 2 2 2 0 Tumour suppressor protein Phage_Mu_Gam PF07352.12 OAP64712.1 - 0.49 10.3 3.7 16 5.3 0.1 3.5 3 0 0 3 3 3 0 Bacteriophage Mu Gam like protein THOC7 PF05615.13 OAP64712.1 - 0.53 10.6 9.8 0.28 11.5 0.2 3.6 4 0 0 4 4 4 0 Tho complex subunit 7 CsbD PF05532.12 OAP64712.1 - 1.4 8.8 3.1 4.6 7.2 0.1 3.0 3 0 0 3 3 3 0 CsbD-like Ribosomal_L4 PF00573.22 OAP64713.1 - 4.9e-34 117.7 0.2 6.3e-34 117.3 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 OAP64713.1 - 1.1e-28 99.1 0.1 1.1e-28 99.1 0.1 1.9 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain Fungal_trans PF04082.18 OAP64715.1 - 1.5e-14 53.7 0.1 2.4e-14 53.0 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain FERM_N PF09379.10 OAP64715.1 - 0.13 12.2 0.1 0.39 10.7 0.0 1.8 2 0 0 2 2 2 0 FERM N-terminal domain BCS1_N PF08740.11 OAP64716.1 - 1e-32 113.6 0.8 1e-32 113.6 0.8 2.0 3 0 0 3 3 3 1 BCS1 N terminal AAA PF00004.29 OAP64716.1 - 1.4e-16 61.1 0.0 2e-07 31.5 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 OAP64716.1 - 0.013 15.3 0.0 0.023 14.4 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 OAP64716.1 - 0.045 14.1 0.9 0.2 12.0 0.5 2.4 1 1 1 2 2 2 0 AAA ATPase domain AAA_5 PF07728.14 OAP64716.1 - 0.086 12.8 0.0 0.24 11.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 OAP64716.1 - 0.13 12.4 0.0 0.3 11.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain ATPase PF06745.13 OAP64716.1 - 0.15 11.4 0.0 0.3 10.4 0.0 1.4 1 0 0 1 1 1 0 KaiC Adaptin_binding PF10199.9 OAP64716.1 - 2.5 8.7 8.8 5.4 7.6 3.4 2.7 3 0 0 3 3 3 0 Alpha and gamma adaptin binding protein p34 AMP-binding PF00501.28 OAP64718.1 - 2.5e-38 131.8 0.0 3.4e-38 131.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 OAP64718.1 - 3e-07 30.2 0.0 5.6e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 OAP64718.1 - 0.062 14.3 0.0 0.14 13.2 0.0 1.6 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain DUF3357 PF11837.8 OAP64719.1 - 0.051 14.0 0.1 0.13 12.7 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) SEP PF08059.13 OAP64720.1 - 7.5e-25 87.3 0.9 1.1e-24 86.7 0.2 1.7 2 0 0 2 2 2 1 SEP domain UBX PF00789.20 OAP64720.1 - 1e-08 35.3 0.0 1.8e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.6 OAP64720.1 - 9.3e-06 25.4 5.5 4.1e-05 23.3 5.5 1.9 1 1 0 1 1 1 1 UBA-like domain 60KD_IMP PF02096.20 OAP64721.1 - 1.5e-18 67.2 1.1 1.5e-18 67.2 1.1 2.1 2 0 0 2 2 2 1 60Kd inner membrane protein DUF4723 PF15851.5 OAP64721.1 - 0.013 15.6 0.3 0.035 14.2 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4723) DUF5403 PF17395.2 OAP64721.1 - 0.13 12.6 0.1 0.48 10.8 0.0 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5403) EMC3_TMCO1 PF01956.16 OAP64721.1 - 0.66 9.7 0.0 0.66 9.7 0.0 3.1 3 0 0 3 3 3 0 Integral membrane protein EMC3/TMCO1-like DUF4786 PF16027.5 OAP64721.1 - 1.2 9.7 10.1 2 9.0 2.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4786) DctP PF03480.13 OAP64721.1 - 2.4 7.4 6.8 6.4 6.0 2.1 2.3 2 0 0 2 2 2 0 Bacterial extracellular solute-binding protein, family 7 DUF4140 PF13600.6 OAP64721.1 - 6.8 7.2 8.7 15 6.1 0.0 3.2 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) TPP_enzyme_N PF02776.18 OAP64722.1 - 2.4e-45 154.2 0.0 5.2e-45 153.1 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 OAP64722.1 - 9.4e-24 83.9 0.1 5.3e-23 81.5 0.0 2.2 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 OAP64722.1 - 2.1e-22 79.4 0.0 3.7e-22 78.6 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain GST_N_3 PF13417.6 OAP64723.1 - 9.3e-07 29.2 0.0 1.7e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAP64723.1 - 0.0045 17.0 0.1 0.0093 16.0 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain adh_short_C2 PF13561.6 OAP64724.1 - 2.9e-46 157.9 0.0 3.9e-46 157.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP64724.1 - 1.1e-36 126.2 0.2 1.3e-32 112.9 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 OAP64724.1 - 1.1e-09 38.5 0.0 2.2e-09 37.5 0.0 1.5 1 1 0 1 1 1 1 KR domain Ceramidase PF05875.12 OAP64725.1 - 1.3e-62 211.7 12.3 1.4e-62 211.5 12.3 1.0 1 0 0 1 1 1 1 Ceramidase DUF4212 PF13937.6 OAP64725.1 - 0.0022 18.3 8.4 0.0031 17.8 0.5 3.0 2 1 1 3 3 3 1 Domain of unknown function (DUF4212) Leader_Trp PF08255.11 OAP64725.1 - 0.04 13.8 1.0 0.16 12.0 1.0 2.1 1 0 0 1 1 1 0 Trp-operon Leader Peptide HPP PF04982.13 OAP64725.1 - 0.14 12.4 3.8 0.11 12.7 1.4 2.0 2 0 0 2 2 2 0 HPP family DUF5090 PF17009.5 OAP64725.1 - 0.47 10.4 2.3 4.5 7.2 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF5090) p450 PF00067.22 OAP64726.1 - 5.5e-56 190.2 0.0 7.4e-56 189.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_23 PF13489.6 OAP64727.1 - 4.9e-20 72.0 0.0 7.4e-20 71.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAP64727.1 - 2.3e-08 34.6 0.0 7.3e-08 33.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAP64727.1 - 2.4e-06 28.1 0.0 5.6e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAP64727.1 - 0.0004 21.1 0.0 0.0039 17.9 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain DUF938 PF06080.12 OAP64727.1 - 0.0045 16.8 0.0 0.0089 15.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_31 PF13847.6 OAP64727.1 - 0.005 16.6 0.0 0.73 9.6 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_16 PF10294.9 OAP64727.1 - 0.0075 16.0 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_2 PF00891.18 OAP64727.1 - 0.014 14.7 0.0 0.22 10.8 0.0 2.3 2 0 0 2 2 2 0 O-methyltransferase domain MTS PF05175.14 OAP64727.1 - 0.017 14.7 0.0 0.035 13.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.13 OAP64727.1 - 0.02 14.3 0.0 0.036 13.5 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.19 OAP64727.1 - 0.032 14.3 0.1 0.084 13.0 0.0 1.6 2 0 0 2 2 2 0 FtsJ-like methyltransferase Ubie_methyltran PF01209.18 OAP64727.1 - 0.042 13.2 0.0 1.3 8.4 0.0 2.4 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family NmrA PF05368.13 OAP64728.1 - 2.8e-10 40.2 0.0 7.9e-09 35.4 0.0 2.1 1 1 0 1 1 1 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 OAP64728.1 - 0.00038 20.7 0.0 0.0011 19.3 0.0 1.7 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain KR PF08659.10 OAP64728.1 - 0.019 14.9 0.1 0.032 14.1 0.1 1.3 1 0 0 1 1 1 0 KR domain TMEM154 PF15102.6 OAP64729.1 - 0.0045 16.9 3.3 0.017 15.0 0.0 2.4 1 1 0 2 2 2 1 TMEM154 protein family BatD PF13584.6 OAP64729.1 - 0.0046 15.8 2.9 0.092 11.5 0.1 2.3 1 1 1 2 2 2 2 Oxygen tolerance DUF5305 PF17231.2 OAP64729.1 - 0.089 12.2 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5305) DUF1180 PF06679.12 OAP64729.1 - 0.15 12.5 3.0 0.35 11.2 3.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) ERG4_ERG24 PF01222.17 OAP64730.1 - 5.1e-145 483.5 20.6 5.9e-145 483.3 20.6 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family AA_permease_2 PF13520.6 OAP64732.1 - 9.8e-54 182.8 57.3 1.3e-53 182.4 57.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAP64732.1 - 1.5e-19 69.9 44.7 2.1e-19 69.5 44.7 1.1 1 0 0 1 1 1 1 Amino acid permease Gram_pos_anchor PF00746.21 OAP64732.1 - 1.6 8.7 0.0 1.6 8.7 0.0 2.9 4 0 0 4 4 4 0 LPXTG cell wall anchor motif DUF4131 PF13567.6 OAP64732.1 - 2.4 7.8 0.0 2.4 7.8 0.0 3.9 3 1 1 4 4 4 0 Domain of unknown function (DUF4131) NAP PF00956.18 OAP64733.1 - 1.3e-19 70.4 3.7 5.4e-19 68.4 3.3 2.0 1 1 1 2 2 2 1 Nucleosome assembly protein (NAP) Pepdidase_M14_N PF18027.1 OAP64733.1 - 0.12 12.8 0.0 0.24 11.8 0.0 1.5 1 0 0 1 1 1 0 Cytosolic carboxypeptidase N-terminal domain Syntaxin-6_N PF09177.11 OAP64734.1 - 2.9e-28 98.3 0.9 3.8e-28 97.9 0.3 1.5 2 0 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.19 OAP64734.1 - 0.0029 17.6 1.0 0.0058 16.6 1.0 1.5 1 0 0 1 1 1 1 SNARE domain GCIP PF13324.6 OAP64734.1 - 0.0056 16.3 0.8 0.011 15.3 0.6 1.7 1 1 0 1 1 1 1 Grap2 and cyclin-D-interacting NPV_P10 PF05531.12 OAP64734.1 - 0.025 15.0 0.5 18 5.9 0.0 3.1 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein AMP-binding PF00501.28 OAP64736.1 - 2.7e-18 65.8 0.0 4e-18 65.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Oest_recep PF02159.15 OAP64736.1 - 0.059 13.8 0.3 3.8 8.0 0.3 2.4 2 0 0 2 2 2 0 Oestrogen receptor FAD_binding_3 PF01494.19 OAP64737.1 - 6.7e-27 94.6 0.0 2.6e-26 92.7 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAP64737.1 - 1.8e-11 44.3 4.7 2.1e-06 27.6 1.0 2.6 2 1 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAP64737.1 - 2.5e-10 40.1 0.9 3.1e-05 23.4 0.3 2.2 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 OAP64737.1 - 5.5e-08 32.5 0.4 0.0079 15.5 0.1 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OAP64737.1 - 2.9e-07 30.6 0.3 6.2e-07 29.5 0.3 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 OAP64737.1 - 5.1e-07 29.1 0.7 5.1e-07 29.1 0.7 2.0 3 0 0 3 3 3 1 FAD binding domain Trp_halogenase PF04820.14 OAP64737.1 - 4.2e-06 25.9 0.2 0.0093 14.9 0.0 2.1 2 0 0 2 2 2 2 Tryptophan halogenase Pyr_redox PF00070.27 OAP64737.1 - 5e-06 27.0 0.2 0.00022 21.7 0.2 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OAP64737.1 - 7.8e-06 25.2 0.5 0.099 11.7 0.0 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox_3 PF13738.6 OAP64737.1 - 7.7e-05 22.1 0.2 0.01 15.1 0.4 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OAP64737.1 - 0.00017 20.8 0.1 0.0016 17.6 0.1 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 OAP64737.1 - 0.00023 20.6 0.2 0.00041 19.8 0.2 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase SE PF08491.10 OAP64737.1 - 0.00035 19.7 0.0 0.0018 17.4 0.0 1.8 2 0 0 2 2 2 1 Squalene epoxidase HI0933_like PF03486.14 OAP64737.1 - 0.00045 19.0 0.4 0.0035 16.1 0.2 2.0 2 0 0 2 2 2 1 HI0933-like protein AlaDh_PNT_C PF01262.21 OAP64737.1 - 0.0021 17.4 0.0 0.0039 16.5 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 OAP64737.1 - 0.003 16.9 0.1 0.0055 16.0 0.1 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 OAP64737.1 - 0.018 15.0 3.4 2.2 8.2 0.3 2.8 3 0 0 3 3 3 0 FAD-NAD(P)-binding ApbA PF02558.16 OAP64737.1 - 0.046 13.3 0.1 0.086 12.5 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA K_oxygenase PF13434.6 OAP64737.1 - 0.19 10.9 0.0 17 4.4 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) HET PF06985.11 OAP64738.1 - 1.1e-11 45.2 1.3 2e-11 44.4 1.3 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Podoplanin PF05808.11 OAP64739.1 - 0.0085 16.2 2.4 0.015 15.4 2.4 1.3 1 0 0 1 1 1 1 Podoplanin Rax2 PF12768.7 OAP64739.1 - 0.026 14.0 0.0 0.041 13.4 0.0 1.3 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Mid2 PF04478.12 OAP64739.1 - 0.08 12.8 0.2 0.14 12.0 0.2 1.3 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor SKG6 PF08693.10 OAP64739.1 - 0.087 12.2 1.7 0.21 11.0 1.7 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain NMO PF03060.15 OAP64740.1 - 3.8e-54 184.3 0.2 3.1e-53 181.3 0.2 1.9 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 OAP64740.1 - 1.5e-14 53.8 0.0 8e-11 41.5 0.0 2.1 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 OAP64740.1 - 0.0023 17.0 1.2 0.0046 16.0 1.2 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 OAP64740.1 - 0.13 11.4 1.5 0.39 9.8 1.5 1.9 1 1 0 1 1 1 0 Conserved region in glutamate synthase RTA1 PF04479.13 OAP64741.1 - 1.1e-65 221.1 3.1 1.7e-65 220.5 3.1 1.3 1 0 0 1 1 1 1 RTA1 like protein Hid1 PF12722.7 OAP64742.1 - 2.8e-297 988.3 0.0 8.3e-297 986.8 0.0 1.6 1 1 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 OAP64742.1 - 3e-101 339.8 0.2 3.6e-101 339.5 0.2 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein DUF4820 PF16091.5 OAP64742.1 - 0.075 12.4 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) NPCC PF08058.11 OAP64743.1 - 2e-18 66.7 0.0 3.1e-18 66.1 0.0 1.3 1 0 0 1 1 1 1 Nuclear pore complex component DUF1501 PF07394.12 OAP64743.1 - 0.068 12.2 0.2 0.095 11.7 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) Anticodon_1 PF08264.13 OAP64743.1 - 0.22 11.5 0.0 0.39 10.7 0.0 1.3 1 0 0 1 1 1 0 Anticodon-binding domain of tRNA HpcH_HpaI PF03328.14 OAP64744.1 - 6.9e-37 126.7 0.0 8.9e-37 126.4 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family NAD_binding_1 PF00175.21 OAP64745.1 - 4.3e-11 43.4 0.0 9.8e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.28 OAP64745.1 - 6.6e-11 42.2 0.0 2.7e-10 40.2 0.0 2.0 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain IDO PF01231.18 OAP64745.1 - 4.2e-10 39.0 0.0 1.3e-09 37.4 0.0 1.8 2 0 0 2 2 2 1 Indoleamine 2,3-dioxygenase FAD_binding_1 PF00667.20 OAP64745.1 - 3e-08 33.5 0.0 9.9e-08 31.8 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain Glyco_hydro_18 PF00704.28 OAP64746.1 - 1.5e-17 64.3 0.0 1.9e-17 64.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 PhoD PF09423.10 OAP64747.1 - 2.4e-38 132.1 0.0 5.7e-38 130.8 0.0 1.7 1 1 0 1 1 1 1 PhoD-like phosphatase Pur_ac_phosph_N PF16656.5 OAP64747.1 - 0.089 13.4 0.4 0.25 11.9 0.4 1.7 1 0 0 1 1 1 0 Purple acid Phosphatase, N-terminal domain bZIP_1 PF00170.21 OAP64748.1 - 5.4e-08 32.8 13.5 7.9e-08 32.3 11.6 2.1 1 1 1 2 2 2 2 bZIP transcription factor Hap4_Hap_bind PF10297.9 OAP64748.1 - 2.6e-07 30.5 6.7 6e-07 29.4 6.7 1.7 1 0 0 1 1 1 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 DUF812 PF05667.11 OAP64748.1 - 0.00038 19.5 0.1 0.00073 18.5 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF812) bZIP_2 PF07716.15 OAP64748.1 - 0.00075 19.5 7.8 0.00075 19.5 7.8 2.0 2 0 0 2 2 2 1 Basic region leucine zipper DUF4757 PF15949.5 OAP64748.1 - 0.028 14.9 3.8 0.075 13.5 0.6 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4757) DUF2408 PF10303.9 OAP64748.1 - 0.076 13.6 0.3 0.13 12.8 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) dsrm PF00035.26 OAP64748.1 - 0.13 13.0 0.0 0.29 11.9 0.0 1.6 1 0 0 1 1 1 0 Double-stranded RNA binding motif HlyD_2 PF12700.7 OAP64748.1 - 0.17 10.6 0.6 0.24 10.1 0.6 1.1 1 0 0 1 1 1 0 HlyD family secretion protein Fmp27_WPPW PF10359.9 OAP64748.1 - 0.18 10.6 1.1 0.24 10.2 1.1 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Golgin_A5 PF09787.9 OAP64748.1 - 0.37 10.2 5.0 0.58 9.6 5.0 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 V_ATPase_I PF01496.19 OAP64748.1 - 1.6 6.5 3.4 2.2 6.1 3.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2188 PF09954.9 OAP64748.1 - 6.8 6.9 6.0 0.45 10.7 0.4 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2188) MFS_1 PF07690.16 OAP64749.1 - 5.9e-27 94.5 44.3 5.9e-27 94.5 44.3 3.6 2 2 2 4 4 4 3 Major Facilitator Superfamily Mito_carr PF00153.27 OAP64749.1 - 3.4e-11 42.9 2.9 0.0078 16.1 0.1 5.3 3 2 0 3 3 3 3 Mitochondrial carrier protein Sugar_tr PF00083.24 OAP64749.1 - 1e-06 27.9 8.5 1e-06 27.9 8.5 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter Glyco_hydro_71 PF03659.14 OAP64750.1 - 1.5e-130 435.4 6.6 1.5e-130 435.4 6.6 1.6 1 1 1 2 2 2 1 Glycosyl hydrolase family 71 Rrp40_N PF18311.1 OAP64750.1 - 0.16 12.0 0.4 9.7 6.2 0.1 2.5 2 0 0 2 2 2 0 Exosome complex exonuclease Rrp40 N-terminal domain Fer2 PF00111.27 OAP64751.1 - 2e-14 53.3 1.3 2.9e-14 52.8 1.3 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Rrp15p PF07890.12 OAP64752.1 - 1.2e-37 129.2 13.6 1.2e-37 129.2 13.6 2.2 2 1 0 2 2 2 1 Rrp15p CAF1A PF12253.8 OAP64752.1 - 3.9 7.7 14.2 0.21 11.8 2.8 2.8 1 1 1 2 2 2 0 Chromatin assembly factor 1 subunit A SRP54 PF00448.22 OAP64753.1 - 8.7e-71 237.6 2.3 8.7e-71 237.6 2.3 1.8 2 0 0 2 2 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 OAP64753.1 - 5.9e-31 107.0 2.6 5.9e-31 107.0 2.6 3.9 2 1 2 4 4 3 1 Signal peptide binding domain SRP54_N PF02881.19 OAP64753.1 - 6.5e-18 64.7 0.1 1.8e-17 63.3 0.0 1.9 2 0 0 2 2 1 1 SRP54-type protein, helical bundle domain AAA_33 PF13671.6 OAP64753.1 - 2.7e-05 24.4 0.3 6.1e-05 23.2 0.0 1.9 2 0 0 2 2 1 1 AAA domain Zeta_toxin PF06414.12 OAP64753.1 - 0.00024 20.4 0.0 0.00046 19.5 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin cobW PF02492.19 OAP64753.1 - 0.00029 20.5 0.6 0.0012 18.5 0.6 2.0 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain 6PF2K PF01591.18 OAP64753.1 - 0.00042 19.7 0.0 0.00081 18.8 0.0 1.4 1 0 0 1 1 1 1 6-phosphofructo-2-kinase AAA_17 PF13207.6 OAP64753.1 - 0.00044 20.7 2.6 0.00082 19.8 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 OAP64753.1 - 0.00063 20.2 0.0 0.0013 19.1 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain CbiA PF01656.23 OAP64753.1 - 0.0012 19.0 0.0 0.0029 17.7 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain APS_kinase PF01583.20 OAP64753.1 - 0.0017 18.3 0.0 0.0053 16.7 0.0 1.8 2 0 0 2 2 1 1 Adenylylsulphate kinase AAA_30 PF13604.6 OAP64753.1 - 0.0029 17.4 1.4 0.0051 16.5 0.1 2.0 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 OAP64753.1 - 0.0082 16.2 0.1 0.02 14.9 0.1 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SRPRB PF09439.10 OAP64753.1 - 0.0098 15.3 0.8 5.9 6.3 0.1 3.3 2 1 0 3 3 3 1 Signal recognition particle receptor beta subunit Thymidylate_kin PF02223.17 OAP64753.1 - 0.021 14.5 0.1 0.06 13.0 0.1 1.7 1 0 0 1 1 1 0 Thymidylate kinase AAA_24 PF13479.6 OAP64753.1 - 0.032 14.0 0.3 0.15 11.8 0.1 2.2 3 0 0 3 3 3 0 AAA domain TPP_enzyme_N PF02776.18 OAP64753.1 - 0.039 13.6 0.3 0.3 10.7 0.1 2.2 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain MobB PF03205.14 OAP64753.1 - 0.045 13.6 0.1 0.15 12.0 0.0 1.9 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_31 PF13614.6 OAP64753.1 - 0.049 13.5 0.0 0.15 12.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 OAP64753.1 - 0.055 13.8 0.1 0.17 12.2 0.1 1.8 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 OAP64753.1 - 0.055 13.2 0.3 0.26 11.0 0.1 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 OAP64753.1 - 0.058 13.7 0.1 0.31 11.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 OAP64753.1 - 0.076 13.6 0.0 0.2 12.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 OAP64753.1 - 0.1 12.8 0.1 0.21 11.8 0.1 1.5 1 0 0 1 1 1 0 AAA domain Arf PF00025.21 OAP64753.1 - 0.13 11.7 0.1 0.39 10.2 0.0 1.8 2 0 0 2 2 2 0 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OAP64753.1 - 0.14 12.2 0.2 1.4 9.1 0.1 2.7 2 1 0 2 2 2 0 50S ribosome-binding GTPase Tim17 PF02466.19 OAP64754.1 - 1.4e-38 131.7 5.4 1.4e-38 131.7 5.4 1.7 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family DUF4766 PF15973.5 OAP64754.1 - 1.1 9.9 7.1 1.4 9.5 7.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4766) ABA_WDS PF02496.16 OAP64754.1 - 1.6 9.3 5.0 4.8 7.7 0.4 3.1 2 2 0 3 3 3 0 ABA/WDS induced protein ADH_zinc_N PF00107.26 OAP64755.1 - 6.7e-24 84.3 0.6 1.7e-23 83.0 0.6 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAP64755.1 - 2.6e-21 75.6 1.5 6.8e-21 74.2 1.5 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 OAP64755.1 - 0.0018 19.3 0.2 0.0031 18.6 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pkinase PF00069.25 OAP64756.1 - 3.3e-08 33.2 0.0 0.0025 17.2 0.0 3.3 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 OAP64756.1 - 0.085 12.1 0.0 0.28 10.4 0.0 1.9 3 0 0 3 3 3 0 Protein tyrosine kinase RNA_pol_Rpb2_6 PF00562.28 OAP64757.1 - 8.9e-125 416.8 0.0 1.4e-124 416.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 OAP64757.1 - 2.6e-54 183.8 0.1 4.2e-54 183.2 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 OAP64757.1 - 3.3e-30 104.3 0.1 1.1e-29 102.7 0.1 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 OAP64757.1 - 5.2e-27 94.7 0.4 1.3e-26 93.4 0.4 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.13 OAP64757.1 - 2.2e-24 85.5 0.2 4.8e-24 84.4 0.2 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 OAP64757.1 - 3.1e-19 68.9 0.0 8e-19 67.6 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 OAP64757.1 - 1.3e-12 48.1 0.2 4.3e-12 46.4 0.2 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 PUF PF00806.19 OAP64758.1 - 6.4e-59 192.5 3.8 1.2e-09 37.4 0.1 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat Csm1_B PF18211.1 OAP64758.1 - 0.13 12.1 0.0 0.36 10.7 0.0 1.7 1 0 0 1 1 1 0 Csm1 subunit domain B Dpoe2NT PF12213.8 OAP64758.1 - 0.14 12.5 0.0 0.67 10.3 0.0 2.1 2 0 0 2 2 2 0 DNA polymerases epsilon N terminal ORC5_C PF14630.6 OAP64759.1 - 1.4e-58 198.6 0.0 2e-58 198.2 0.0 1.2 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.6 OAP64759.1 - 1.5e-05 25.5 0.0 3.7e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain ATP-synt_ab PF00006.25 OAP64761.1 - 1.8e-105 351.3 0.0 2.4e-105 350.9 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain Hom_end_hint PF05203.16 OAP64761.1 - 9.7e-85 284.1 0.0 1.5e-84 283.5 0.0 1.3 1 0 0 1 1 1 1 Hom_end-associated Hint ATP-synt_ab_Xtn PF16886.5 OAP64761.1 - 3.1e-46 156.2 0.0 6.8e-46 155.1 0.0 1.6 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension Hom_end PF05204.14 OAP64761.1 - 3.5e-35 120.5 0.0 9e-32 109.5 0.0 2.5 2 0 0 2 2 2 2 Homing endonuclease ATP-synt_ab_N PF02874.23 OAP64761.1 - 3.8e-14 53.0 2.4 8.6e-14 51.8 2.4 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain LAGLIDADG_3 PF14528.6 OAP64761.1 - 5.2e-08 33.1 0.0 0.02 15.2 0.0 2.6 2 0 0 2 2 2 2 LAGLIDADG-like domain Hint PF01079.20 OAP64761.1 - 0.00042 19.9 0.0 0.00082 18.9 0.0 1.4 1 0 0 1 1 1 1 Hint module Hint_2 PF13403.6 OAP64761.1 - 0.00055 20.3 0.1 0.0012 19.2 0.1 1.6 1 0 0 1 1 1 1 Hint domain Vint PF14623.6 OAP64761.1 - 0.011 15.5 0.0 0.051 13.4 0.0 2.0 2 0 0 2 2 2 0 Hint-domain HSBP1 PF06825.12 OAP64761.1 - 0.07 13.0 0.3 0.25 11.3 0.0 2.1 2 0 0 2 2 2 0 Heat shock factor binding protein 1 WD40 PF00400.32 OAP64762.1 - 1.3e-25 89.1 8.8 5.8e-05 23.8 0.3 7.5 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAP64762.1 - 2.9e-11 43.5 3.2 0.0002 21.6 0.1 5.9 2 2 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OAP64762.1 - 3.1e-06 26.4 0.3 0.00044 19.3 0.1 2.9 1 1 2 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein DPPIV_N PF00930.21 OAP64762.1 - 0.00083 18.2 0.6 0.0048 15.7 0.6 2.0 1 1 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Frtz PF11768.8 OAP64762.1 - 0.0011 17.4 0.0 0.0016 16.8 0.0 1.2 1 0 0 1 1 1 1 WD repeat-containing and planar cell polarity effector protein Fritz DUF4221 PF13970.6 OAP64762.1 - 0.012 15.2 0.0 0.053 13.1 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4221) eIF2A PF08662.11 OAP64762.1 - 0.018 14.9 1.9 0.15 11.9 0.3 2.7 2 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 OAP64762.1 - 0.03 14.3 0.0 4.7 7.3 0.0 3.7 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat WD40_like PF17005.5 OAP64762.1 - 0.039 13.3 0.0 0.11 11.8 0.0 1.7 2 0 0 2 2 2 0 WD40-like domain Dynamin_M PF01031.20 OAP64763.1 - 2.2e-104 348.7 0.0 3.9e-104 347.9 0.0 1.4 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 OAP64763.1 - 3.4e-57 193.1 0.1 8.5e-57 191.9 0.1 1.7 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 OAP64763.1 - 6.9e-31 106.3 6.9 1.9e-30 104.8 6.9 1.8 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 OAP64763.1 - 7.4e-05 22.8 0.9 0.00055 20.0 0.9 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 OAP64763.1 - 0.053 12.8 0.3 5.6 6.2 0.0 2.5 2 0 0 2 2 2 0 AIG1 family AAA_15 PF13175.6 OAP64763.1 - 0.065 12.9 1.8 2.6 7.7 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain FeoB_N PF02421.18 OAP64763.1 - 0.097 12.2 0.6 8.4 5.9 0.1 2.7 3 0 0 3 3 3 0 Ferrous iron transport protein B SWIRM PF04433.17 OAP64765.1 - 0.029 14.7 0.1 0.12 12.8 0.1 2.1 1 1 0 1 1 1 0 SWIRM domain DJ-1_PfpI PF01965.24 OAP64766.1 - 4.2e-05 23.4 0.1 0.00027 20.8 0.1 2.3 2 1 0 2 2 2 1 DJ-1/PfpI family PLDc_N PF13396.6 OAP64767.1 - 7.5e-12 45.0 2.3 1.8e-11 43.8 2.3 1.7 1 0 0 1 1 1 1 Phospholipase_D-nuclease N-terminal p450 PF00067.22 OAP64768.1 - 3.7e-50 171.0 0.0 4.4e-50 170.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF4880 PF16220.5 OAP64768.1 - 0.073 13.0 1.2 0.15 11.9 1.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4880) Methyltransf_23 PF13489.6 OAP64769.1 - 4.4e-18 65.7 0.0 1.8e-17 63.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAP64769.1 - 4.1e-12 46.6 0.0 8.3e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAP64769.1 - 2e-07 30.9 0.0 1.6e-06 28.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAP64769.1 - 3.6e-07 30.7 0.0 6.7e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAP64769.1 - 3.2e-06 27.8 0.0 1.6e-05 25.6 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 OAP64769.1 - 4.1e-05 23.0 0.0 9.3e-05 21.8 0.0 1.5 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase FtsJ PF01728.19 OAP64769.1 - 0.0015 18.6 0.0 0.0074 16.4 0.0 1.9 2 0 0 2 2 2 1 FtsJ-like methyltransferase MTS PF05175.14 OAP64769.1 - 0.0046 16.5 0.0 0.015 14.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.18 OAP64769.1 - 0.014 14.7 0.0 0.018 14.3 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_16 PF10294.9 OAP64769.1 - 0.031 14.0 0.0 0.048 13.4 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_4 PF02390.17 OAP64769.1 - 0.054 13.0 0.0 0.15 11.5 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase PATR PF12951.7 OAP64769.1 - 0.16 12.1 1.0 0.29 11.3 1.0 1.3 1 0 0 1 1 1 0 Passenger-associated-transport-repeat PrmA PF06325.13 OAP64769.1 - 0.21 10.9 0.0 0.35 10.2 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Arylsulfotran_2 PF14269.6 OAP64770.1 - 1.9e-60 204.8 0.6 3.2e-60 204.0 0.6 1.3 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 OAP64770.1 - 1.2e-11 44.1 0.4 5.8e-10 38.6 0.4 2.3 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) FAD_binding_3 PF01494.19 OAP64771.1 - 4.4e-22 78.8 0.0 7.1e-22 78.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 OAP64771.1 - 4.6e-06 25.9 0.1 0.0064 15.6 0.1 2.5 2 1 0 2 2 2 2 Lycopene cyclase protein DAO PF01266.24 OAP64771.1 - 6.9e-06 25.9 0.2 0.0027 17.4 0.1 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAP64771.1 - 2.5e-05 24.4 0.0 5.5e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SE PF08491.10 OAP64771.1 - 7.6e-05 21.9 0.0 0.00036 19.7 0.0 2.0 1 1 0 1 1 1 1 Squalene epoxidase Thi4 PF01946.17 OAP64771.1 - 0.00054 19.3 0.0 0.00095 18.5 0.0 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 OAP64771.1 - 0.00085 19.3 0.3 0.0053 16.8 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding Trp_halogenase PF04820.14 OAP64771.1 - 0.015 14.2 0.0 1.6 7.5 0.0 2.2 2 0 0 2 2 2 0 Tryptophan halogenase Pyr_redox_2 PF07992.14 OAP64771.1 - 0.022 14.0 0.1 0.044 13.0 0.1 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAP64771.1 - 0.03 13.6 0.0 0.052 12.8 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAP64771.1 - 0.12 11.1 0.0 0.21 10.3 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein K_oxygenase PF13434.6 OAP64771.1 - 0.12 11.5 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Molybdopterin PF00384.22 OAP64772.1 - 6e-69 233.1 0.0 1.2e-66 225.5 0.0 2.4 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fer2_4 PF13510.6 OAP64772.1 - 1.9e-20 72.7 0.1 4.4e-20 71.5 0.1 1.7 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH_dhqG_C PF09326.11 OAP64772.1 - 4.6e-17 62.4 0.0 1.1e-16 61.2 0.0 1.7 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit G, C-terminal NADH-G_4Fe-4S_3 PF10588.9 OAP64772.1 - 5.3e-17 61.1 0.2 5.3e-17 61.1 0.2 1.9 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2 PF00111.27 OAP64772.1 - 1.2e-08 34.7 0.5 1.2e-08 34.7 0.5 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Lyx_isomer PF07385.12 OAP64772.1 - 0.089 12.0 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 D-lyxose isomerase TPP_enzyme_M PF00205.22 OAP64772.1 - 0.13 12.0 0.0 0.3 10.8 0.0 1.6 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain EXS PF03124.14 OAP64773.1 - 5.2e-95 318.6 32.6 6.4e-95 318.3 32.6 1.1 1 0 0 1 1 1 1 EXS family SPX PF03105.19 OAP64773.1 - 1.5e-57 196.3 14.5 1.5e-57 196.3 14.5 2.8 2 1 0 2 2 2 1 SPX domain DIOX_N PF14226.6 OAP64774.1 - 1.3e-29 103.3 0.0 3.5e-29 102.0 0.0 1.8 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OAP64774.1 - 5.8e-14 52.4 0.0 1e-13 51.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily SR-25 PF10500.9 OAP64774.1 - 4.7 6.7 6.9 7.4 6.1 6.9 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein NmrA PF05368.13 OAP64775.1 - 2.1e-17 63.5 0.1 3e-17 63.0 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAP64775.1 - 7.6e-15 55.3 0.1 1.1e-14 54.8 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 OAP64775.1 - 3.3e-09 37.1 0.1 6.9e-09 36.1 0.1 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 OAP64775.1 - 4.2e-05 23.1 0.0 0.0012 18.4 0.0 2.2 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 OAP64775.1 - 0.0004 19.7 0.3 0.00096 18.5 0.3 1.7 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Semialdhyde_dh PF01118.24 OAP64775.1 - 0.00041 20.8 0.1 0.00077 19.9 0.1 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 OAP64775.1 - 0.0012 18.9 0.1 0.0021 18.2 0.1 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus F420_oxidored PF03807.17 OAP64775.1 - 0.0039 17.7 0.1 0.011 16.3 0.1 1.8 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent CbiJ PF02571.14 OAP64775.1 - 0.008 15.7 0.7 0.013 15.0 0.7 1.3 1 0 0 1 1 1 1 Precorrin-6x reductase CbiJ/CobK LytR_C PF13399.6 OAP64775.1 - 0.0094 16.9 0.3 0.12 13.4 0.3 2.2 2 0 0 2 2 2 1 LytR cell envelope-related transcriptional attenuator adh_short PF00106.25 OAP64775.1 - 0.01 15.3 0.3 0.017 14.6 0.3 1.5 1 0 0 1 1 1 0 short chain dehydrogenase Glyco_trans_4_2 PF13477.6 OAP64775.1 - 0.011 15.7 0.0 0.035 14.1 0.0 1.8 2 0 0 2 2 2 0 Glycosyl transferase 4-like 3HCDH_N PF02737.18 OAP64775.1 - 0.024 14.5 1.1 0.098 12.5 0.4 2.1 1 1 1 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.17 OAP64775.1 - 0.026 13.6 0.0 0.04 13.0 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Ldh_1_N PF00056.23 OAP64775.1 - 0.047 13.8 0.1 0.079 13.1 0.1 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 OAP64775.1 - 0.06 13.5 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 OAP64775.1 - 0.15 11.4 0.0 0.51 9.7 0.0 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ERCC4 PF02732.15 OAP64776.1 - 2.5e-18 66.8 0.0 5.1e-18 65.7 0.0 1.6 1 1 0 1 1 1 1 ERCC4 domain LSM PF01423.22 OAP64776.1 - 0.064 13.0 0.1 0.26 11.0 0.0 2.0 2 0 0 2 2 2 0 LSM domain LETM1 PF07766.13 OAP64776.1 - 0.22 10.8 11.0 0.23 10.8 9.7 1.6 2 0 0 2 2 2 0 LETM1-like protein Glycos_transf_1 PF00534.20 OAP64777.1 - 1.3e-33 116.0 0.0 1.8e-31 109.0 0.0 2.2 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 OAP64777.1 - 2.5e-15 56.9 0.0 4.1e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 OAP64777.1 - 9.3e-14 52.0 0.0 3.4e-13 50.2 0.0 2.0 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 OAP64777.1 - 3.6e-07 30.7 0.0 2.5e-06 28.0 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 OAP64777.1 - 6.6e-06 26.4 0.0 1.4e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 ALG11_N PF15924.5 OAP64777.1 - 0.00061 19.9 0.1 0.12 12.4 0.1 2.8 1 1 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glyco_hydro_72 PF03198.14 OAP64778.1 - 1.7e-121 405.4 0.0 2.1e-121 405.1 0.0 1.0 1 0 0 1 1 1 1 Glucanosyltransferase HALZ PF02183.18 OAP64778.1 - 0.14 12.4 0.4 0.14 12.4 0.4 1.7 2 0 0 2 2 2 0 Homeobox associated leucine zipper MARVEL PF01284.23 OAP64779.1 - 0.0024 17.9 14.0 0.0035 17.4 14.0 1.3 1 0 0 1 1 1 1 Membrane-associating domain Flavokinase PF01687.17 OAP64780.1 - 3.4e-10 40.2 0.0 7.1e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Riboflavin kinase FAD_binding_3 PF01494.19 OAP64781.1 - 4.6e-14 52.4 0.0 8.1e-14 51.6 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain SE PF08491.10 OAP64781.1 - 0.017 14.2 0.0 0.029 13.4 0.0 1.3 1 0 0 1 1 1 0 Squalene epoxidase DAO PF01266.24 OAP64781.1 - 0.022 14.4 0.0 2.2 7.8 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase Trp_halogenase PF04820.14 OAP64781.1 - 0.041 12.7 0.3 11 4.7 0.0 3.0 3 0 0 3 3 3 0 Tryptophan halogenase Pyr_redox_2 PF07992.14 OAP64781.1 - 0.061 12.5 0.0 7.1 5.8 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAP64781.1 - 0.091 13.3 0.1 24 5.6 0.0 3.2 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase ADH_N PF08240.12 OAP64782.1 - 1.1e-30 105.7 3.0 1.1e-30 105.7 3.0 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAP64782.1 - 4.6e-24 84.8 3.2 6.4e-24 84.4 2.5 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAP64782.1 - 4.9e-06 27.6 0.3 8e-06 26.9 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 OAP64782.1 - 1.3e-05 24.8 1.5 1.9e-05 24.3 1.5 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus Shikimate_DH PF01488.20 OAP64782.1 - 0.0015 18.6 0.0 0.0026 17.8 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase adh_short PF00106.25 OAP64782.1 - 0.0029 17.1 0.1 0.0066 15.9 0.1 1.6 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_7 PF13241.6 OAP64782.1 - 0.0077 16.7 1.1 0.018 15.5 0.4 1.9 2 0 0 2 2 2 1 Putative NAD(P)-binding Pyr_redox PF00070.27 OAP64782.1 - 0.054 14.1 1.8 1.1 9.9 2.1 2.7 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 OAP64782.1 - 0.083 12.1 0.2 0.13 11.5 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain F420_oxidored PF03807.17 OAP64782.1 - 0.1 13.2 0.2 0.23 12.1 0.1 1.7 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent MFS_1 PF07690.16 OAP64783.1 - 2.6e-41 141.7 56.5 7.1e-41 140.3 53.4 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAP64783.1 - 3.4e-11 42.7 17.4 3.4e-11 42.7 17.4 3.0 2 1 1 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 OAP64783.1 - 2.3e-10 39.5 26.0 4.4e-10 38.6 25.4 1.7 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) CENP-S PF15630.6 OAP64784.1 - 1.9e-32 111.5 0.0 2.5e-32 111.1 0.0 1.1 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 OAP64784.1 - 6e-08 32.8 0.0 7.4e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold PGA2 PF07543.12 OAP64785.1 - 3e-06 27.3 0.1 5e-06 26.5 0.1 1.4 1 0 0 1 1 1 1 Protein trafficking PGA2 AtuA PF07287.11 OAP64786.1 - 1.1e-122 409.2 0.0 1.3e-122 408.9 0.0 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA RRM_1 PF00076.22 OAP64787.1 - 1.3e-44 149.9 0.0 7.3e-17 61.0 0.0 3.1 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 OAP64787.1 - 5.7e-06 26.2 0.1 0.0015 18.5 0.0 3.1 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 OAP64787.1 - 0.00014 21.8 0.0 0.0012 18.9 0.0 2.3 3 0 0 3 3 3 1 RNA binding motif RRM_occluded PF16842.5 OAP64787.1 - 0.00085 19.1 0.0 0.055 13.3 0.0 2.4 2 0 0 2 2 2 1 Occluded RNA-recognition motif RRM_7 PF16367.5 OAP64787.1 - 0.00086 19.4 0.3 0.049 13.7 0.0 3.0 3 1 0 3 3 3 1 RNA recognition motif RRM_5 PF13893.6 OAP64787.1 - 0.023 14.3 0.0 0.082 12.5 0.0 1.9 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 OAP64787.1 - 0.048 13.9 0.1 2.5 8.3 0.0 3.2 3 1 1 4 4 4 0 Cytosolic domain of 10TM putative phosphate transporter Acetyltransf_1 PF00583.25 OAP64788.1 - 4.3e-05 23.7 0.0 9.8e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OAP64788.1 - 0.00073 19.9 0.0 0.0016 18.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Arf PF00025.21 OAP64789.1 - 3.5e-65 218.7 1.9 3.9e-65 218.5 1.9 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 OAP64789.1 - 1.6e-13 50.5 1.9 3.4e-08 33.1 0.4 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 OAP64789.1 - 1.8e-12 47.5 0.1 2.5e-12 47.1 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 OAP64789.1 - 5.3e-11 42.3 0.1 6.7e-11 42.0 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.22 OAP64789.1 - 2.5e-10 40.2 0.0 2.9e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 OAP64789.1 - 6.9e-08 32.6 0.0 1.1e-07 31.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OAP64789.1 - 2.1e-06 27.4 0.1 5e-05 22.9 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 OAP64789.1 - 1.5e-05 24.5 0.0 2e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 OAP64789.1 - 0.0014 18.1 0.6 0.0053 16.3 0.6 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B cobW PF02492.19 OAP64789.1 - 0.0023 17.5 0.0 0.076 12.6 0.0 2.1 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 OAP64789.1 - 0.038 13.9 0.1 0.83 9.6 0.0 2.1 2 0 0 2 2 2 0 NACHT domain 6PF2K PF01591.18 OAP64789.1 - 0.11 11.8 0.1 0.21 10.9 0.1 1.5 1 1 0 1 1 1 0 6-phosphofructo-2-kinase DUF4045 PF13254.6 OAP64790.1 - 2.4e-106 356.9 33.1 2.4e-106 356.9 33.1 5.8 3 2 2 5 5 5 1 Domain of unknown function (DUF4045) Gelsolin PF00626.22 OAP64790.1 - 1.5e-13 50.4 0.0 0.0007 19.5 0.0 4.2 4 0 0 4 4 4 3 Gelsolin repeat ALO PF04030.14 OAP64791.1 - 7e-87 291.5 0.0 9e-87 291.2 0.0 1.1 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 OAP64791.1 - 1.4e-24 86.4 0.0 2.4e-24 85.7 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Sugar_tr PF00083.24 OAP64792.1 - 6.3e-91 305.5 20.7 8.1e-91 305.1 20.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP64792.1 - 4.1e-13 49.0 48.8 1.4e-08 34.1 16.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MARVEL PF01284.23 OAP64793.1 - 1e-17 64.5 9.3 1.2e-17 64.3 9.3 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF2976 PF11190.8 OAP64793.1 - 0.038 13.8 1.4 0.073 12.9 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) ABC2_membrane_5 PF13346.6 OAP64793.1 - 0.04 13.5 1.3 0.061 12.9 1.3 1.3 1 1 0 1 1 1 0 ABC-2 family transporter protein DUF588 PF04535.12 OAP64793.1 - 0.091 12.5 4.1 1.7 8.5 4.1 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF588) Fungal_trans_2 PF11951.8 OAP64794.1 - 5.8e-10 38.5 0.5 2.1e-08 33.4 0.5 2.2 1 1 0 1 1 1 1 Fungal specific transcription factor domain COesterase PF00135.28 OAP64795.1 - 3.3e-71 240.7 0.0 5.9e-71 239.9 0.0 1.3 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAP64795.1 - 0.00015 21.7 0.8 0.00023 21.1 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OAP64795.1 - 0.013 15.0 0.0 0.022 14.3 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF4336 PF14234.6 OAP64796.1 - 4.5e-16 59.0 1.1 4.6e-12 45.8 0.4 2.7 2 1 0 2 2 2 2 Domain of unknown function (DUF4336) DUF3975 PF13126.6 OAP64797.1 - 0.033 14.6 0.7 0.033 14.6 0.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3975) Patatin PF01734.22 OAP64799.1 - 1.7e-27 96.9 0.1 3.6e-27 95.9 0.1 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase zf-RING_5 PF14634.6 OAP64799.1 - 0.0022 17.9 6.3 0.0022 17.9 6.3 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 OAP64799.1 - 0.0036 17.1 8.2 0.065 13.1 6.5 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) FYVE_2 PF02318.16 OAP64799.1 - 0.066 13.4 2.2 0.28 11.4 2.2 2.1 1 0 0 1 1 1 0 FYVE-type zinc finger zf-C3HC4_4 PF15227.6 OAP64799.1 - 0.069 13.3 7.7 0.68 10.1 7.7 2.6 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 OAP64799.1 - 0.12 12.4 5.1 0.44 10.6 5.1 2.0 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_2 PF13639.6 OAP64799.1 - 3.1 8.2 11.2 1.3 9.4 7.3 2.4 2 0 0 2 2 2 0 Ring finger domain PRP38 PF03371.15 OAP64800.1 - 8.1e-62 208.2 0.0 1.1e-61 207.8 0.0 1.0 1 0 0 1 1 1 1 PRP38 family DUF966 PF06136.13 OAP64801.1 - 0.15 11.8 4.2 0.1 12.3 2.6 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF966) DUF3445 PF11927.8 OAP64802.1 - 3.6e-76 255.7 0.0 4.7e-76 255.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Bac_rhamnosid_N PF08531.10 OAP64802.1 - 0.06 13.2 0.1 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 Alpha-L-rhamnosidase N-terminal domain MMR_HSR1 PF01926.23 OAP64803.1 - 5.2e-14 52.3 0.0 9.5e-14 51.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OAP64803.1 - 1.9e-05 24.2 0.0 3e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 OAP64803.1 - 8.7e-05 22.5 0.0 0.00025 21.0 0.0 1.6 1 1 0 1 1 1 1 RsgA GTPase AIG1 PF04548.16 OAP64803.1 - 0.0013 18.2 0.0 0.0021 17.5 0.0 1.3 1 0 0 1 1 1 1 AIG1 family Septin PF00735.18 OAP64803.1 - 0.0013 18.1 0.0 0.0022 17.4 0.0 1.2 1 0 0 1 1 1 1 Septin Dynamin_N PF00350.23 OAP64803.1 - 0.015 15.3 0.2 0.13 12.3 0.1 2.2 1 1 1 2 2 2 0 Dynamin family AAA_18 PF13238.6 OAP64803.1 - 0.06 13.9 0.0 1.8 9.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 OAP64803.1 - 0.062 13.5 0.0 0.16 12.2 0.0 1.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 OAP64803.1 - 0.072 13.5 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain IIGP PF05049.13 OAP64803.1 - 0.15 11.1 0.0 0.3 10.1 0.0 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) WD40 PF00400.32 OAP64804.1 - 2.9e-16 59.5 23.7 0.17 12.8 0.2 8.9 8 1 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAP64804.1 - 0.015 15.6 0.8 11 6.4 0.0 3.8 5 0 0 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain Rhomboid PF01694.22 OAP64805.1 - 6.1e-24 84.7 8.3 6.1e-24 84.7 8.3 1.9 1 1 1 2 2 2 1 Rhomboid family HSCB_C PF07743.13 OAP64805.1 - 0.011 16.1 6.1 0.026 15.0 6.1 1.5 1 0 0 1 1 1 0 HSCB C-terminal oligomerisation domain AzlD PF05437.12 OAP64805.1 - 0.093 12.9 0.9 12 6.1 0.0 3.0 3 0 0 3 3 3 0 Branched-chain amino acid transport protein (AzlD) MFAP1 PF06991.11 OAP64805.1 - 0.11 12.3 6.8 0.17 11.7 6.8 1.3 1 0 0 1 1 1 0 Microfibril-associated/Pre-mRNA processing DUF3493 PF11998.8 OAP64805.1 - 1.6 8.9 3.3 2.2 8.5 0.2 2.7 3 0 0 3 3 3 0 Low psii accumulation1 / Rep27 Lactamase_B PF00753.27 OAP64806.1 - 1.7e-18 67.3 4.3 2.3e-18 66.9 4.3 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OAP64806.1 - 0.00028 20.5 0.5 0.00042 19.9 0.5 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lipase_3 PF01764.25 OAP64807.1 - 1.1e-33 116.1 0.0 1.7e-33 115.5 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Lipase3_N PF03893.16 OAP64807.1 - 3.7e-09 36.5 0.1 6.6e-09 35.7 0.1 1.4 1 0 0 1 1 1 1 Lipase 3 N-terminal region Hydrolase_4 PF12146.8 OAP64807.1 - 0.00018 20.8 0.0 0.00028 20.2 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_8 PF06259.12 OAP64807.1 - 0.003 17.2 0.1 0.0058 16.3 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase Abhydrolase_6 PF12697.7 OAP64807.1 - 0.008 16.8 0.1 0.01 16.4 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 OAP64807.1 - 0.033 13.9 0.0 0.075 12.7 0.0 1.6 1 0 0 1 1 1 0 PGAP1-like protein DUF2974 PF11187.8 OAP64807.1 - 0.056 13.0 0.4 0.21 11.1 0.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2974) DUF676 PF05057.14 OAP64807.1 - 0.2 11.1 0.3 0.52 9.8 0.0 1.7 2 0 0 2 2 2 0 Putative serine esterase (DUF676) RR_TM4-6 PF06459.12 OAP64810.1 - 9.9 5.9 19.0 0.68 9.7 2.4 3.0 3 0 0 3 3 3 0 Ryanodine Receptor TM 4-6 CAF1C_H4-bd PF12265.8 OAP64811.1 - 9.6e-14 51.4 0.1 5.5e-13 49.0 0.0 2.3 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 OAP64811.1 - 4.4e-12 46.3 10.1 8.9e-07 29.5 0.1 4.0 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAP64811.1 - 9.3e-09 35.5 0.9 0.00055 20.2 0.1 3.3 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 OAP64811.1 - 0.049 13.7 0.0 14 5.8 0.1 2.4 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region UL41A PF17591.2 OAP64811.1 - 0.13 12.4 0.0 0.42 10.8 0.0 1.8 1 0 0 1 1 1 0 Herpesvirus UL41A adh_short_C2 PF13561.6 OAP64812.1 - 1.2e-55 188.6 1.1 1.5e-55 188.3 1.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP64812.1 - 5.3e-48 163.1 1.6 6.5e-48 162.8 1.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAP64812.1 - 1.3e-08 35.0 0.9 5.6e-08 32.9 0.9 1.8 1 1 0 1 1 1 1 KR domain zf-HIT PF04438.16 OAP64813.1 - 2.3e-10 40.1 6.6 4.7e-10 39.2 6.6 1.5 1 0 0 1 1 1 1 HIT zinc finger DENN PF02141.21 OAP64814.1 - 7.9e-40 136.8 0.1 1.5e-39 135.9 0.1 1.5 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 OAP64814.1 - 1.4e-05 25.7 0.1 8.3e-05 23.3 0.0 2.3 2 0 0 2 2 2 1 uDENN domain SMC_Nse1 PF07574.13 OAP64814.1 - 0.0097 15.8 1.4 0.026 14.4 1.4 1.8 1 0 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex DUF3847 PF12958.7 OAP64814.1 - 0.16 12.1 11.3 6.2 7.0 2.9 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3847) TRAF_BIRC3_bd PF16673.5 OAP64814.1 - 0.29 11.0 5.4 11 5.9 0.9 3.0 2 0 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain TMF_TATA_bd PF12325.8 OAP64814.1 - 0.62 10.3 13.5 5.1 7.3 2.6 3.0 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DivIC PF04977.15 OAP64814.1 - 0.69 9.7 17.6 5.3 6.9 1.7 3.7 2 1 1 3 3 3 0 Septum formation initiator Cnn_1N PF07989.11 OAP64814.1 - 2.1 8.6 12.6 2.4 8.4 3.5 3.2 2 1 0 2 2 2 0 Centrosomin N-terminal motif 1 FlaC_arch PF05377.11 OAP64814.1 - 2.2 8.7 4.2 50 4.4 0.1 3.5 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) ADIP PF11559.8 OAP64814.1 - 3.9 7.5 18.9 1.4 9.0 5.4 2.7 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Atg14 PF10186.9 OAP64814.1 - 4.5 6.3 10.1 9.5 5.2 9.1 1.9 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF3450 PF11932.8 OAP64814.1 - 4.5 6.5 19.2 0.17 11.1 3.1 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) 3HCDH_N PF02737.18 OAP64815.1 - 3e-22 79.4 0.0 4.3e-11 43.0 0.0 2.3 1 1 1 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 OAP64815.1 - 4.5e-11 43.2 0.0 9.6e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Pkinase PF00069.25 OAP64816.1 - 4.7e-20 72.1 0.0 8.5e-20 71.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain HEAT PF02985.22 OAP64816.1 - 1e-11 44.0 6.8 0.042 14.1 0.0 7.4 8 0 0 8 8 8 4 HEAT repeat WD40 PF00400.32 OAP64816.1 - 1.1e-10 41.9 1.6 1.5e-06 28.8 0.1 4.8 4 0 0 4 4 4 1 WD domain, G-beta repeat HEAT_2 PF13646.6 OAP64816.1 - 9.1e-06 26.0 0.6 0.17 12.3 0.3 4.4 4 1 2 6 6 6 3 HEAT repeats Pkinase_Tyr PF07714.17 OAP64816.1 - 0.0019 17.5 0.0 0.0031 16.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_EZ PF13513.6 OAP64816.1 - 0.0023 18.4 0.3 11 6.7 0.2 3.7 3 0 0 3 3 3 2 HEAT-like repeat RabGAP-TBC PF00566.18 OAP64817.1 - 9.7e-37 126.7 0.0 4.6e-36 124.5 0.0 1.9 2 0 0 2 2 2 1 Rab-GTPase-TBC domain TilS_C PF11734.8 OAP64817.1 - 0.025 14.0 0.3 0.074 12.5 0.0 1.9 2 0 0 2 2 2 0 TilS substrate C-terminal domain PLDc PF00614.22 OAP64818.1 - 2e-14 53.0 0.2 6.3e-06 26.1 0.0 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 OAP64818.1 - 3e-14 53.0 0.0 8.7e-07 28.9 0.0 3.5 3 1 0 3 3 3 2 PLD-like domain Abhydrolase_6 PF12697.7 OAP64819.1 - 0.0056 17.3 0.6 0.0088 16.7 0.6 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family LCAT PF02450.15 OAP64819.1 - 0.0076 15.5 0.0 0.0097 15.1 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Palm_thioest PF02089.15 OAP64819.1 - 0.13 12.0 0.0 0.37 10.6 0.0 1.6 1 1 1 2 2 2 0 Palmitoyl protein thioesterase DUF676 PF05057.14 OAP64819.1 - 0.24 10.9 0.0 0.36 10.3 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Pex2_Pex12 PF04757.14 OAP64820.1 - 1.4e-47 162.2 0.6 1.8e-47 161.8 0.6 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_2 PF13639.6 OAP64820.1 - 0.0017 18.6 1.0 0.0028 17.9 1.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 OAP64820.1 - 0.15 12.1 0.6 0.29 11.2 0.6 1.4 1 0 0 1 1 1 0 RING-type zinc-finger CDC45 PF02724.14 OAP64820.1 - 0.28 9.4 1.6 0.38 9.0 1.6 1.1 1 0 0 1 1 1 0 CDC45-like protein zf-C3HC4_2 PF13923.6 OAP64820.1 - 0.29 11.0 1.0 0.51 10.2 1.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Dynamin_N PF00350.23 OAP64821.1 - 2.7e-30 105.7 0.0 1.5e-29 103.2 0.0 2.2 3 0 0 3 3 3 1 Dynamin family Dynamin_M PF01031.20 OAP64821.1 - 2e-19 69.9 0.0 3.2e-19 69.2 0.0 1.3 1 0 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.23 OAP64821.1 - 6.7e-06 26.2 0.1 9.4e-05 22.5 0.1 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_21 PF13304.6 OAP64821.1 - 0.011 15.5 0.0 0.044 13.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 OAP64821.1 - 0.017 14.8 0.1 0.093 12.4 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain DUF4455 PF14643.6 OAP64821.1 - 0.019 13.6 2.8 0.038 12.7 2.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4455) AAA_23 PF13476.6 OAP64821.1 - 0.05 14.1 0.1 16 5.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain Nup88 PF10168.9 OAP64821.1 - 0.14 9.9 2.4 0.22 9.3 2.4 1.2 1 0 0 1 1 1 0 Nuclear pore component LXG PF04740.12 OAP64821.1 - 0.28 10.8 3.3 2.3 7.9 0.9 2.6 2 0 0 2 2 2 0 LXG domain of WXG superfamily DUF3886 PF13025.6 OAP64821.1 - 1.4 9.2 9.4 1.6 9.0 7.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3886) KfrA_N PF11740.8 OAP64821.1 - 8.1 7.2 10.2 0.73 10.5 2.8 2.6 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term bZIP_1 PF00170.21 OAP64823.1 - 2e-06 27.8 12.2 4.1e-06 26.8 12.2 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 OAP64823.1 - 0.00017 21.6 9.6 0.00033 20.7 9.6 1.5 1 0 0 1 1 1 1 Basic region leucine zipper 3HCDH_N PF02737.18 OAP64823.1 - 0.012 15.5 2.3 0.017 15.0 2.3 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Macoilin PF09726.9 OAP64823.1 - 0.023 13.3 5.3 0.028 13.0 5.3 1.2 1 0 0 1 1 1 0 Macoilin family bZIP_Maf PF03131.17 OAP64823.1 - 0.16 12.5 10.2 0.086 13.4 7.6 1.9 1 1 0 1 1 1 0 bZIP Maf transcription factor Ndc1_Nup PF09531.10 OAP64823.1 - 1.5 7.5 11.6 1.8 7.2 11.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup GCOM2 PF15328.6 OAP64824.1 - 0.13 12.6 0.8 0.19 12.0 0.8 1.2 1 0 0 1 1 1 0 Putative GRINL1B complex locus protein 2 PAP1 PF08601.10 OAP64824.1 - 5.8 6.5 10.7 7.4 6.2 10.7 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 Pkinase PF00069.25 OAP64825.1 - 2.1e-37 128.9 0.0 3.5e-24 85.6 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAP64825.1 - 2.1e-14 53.5 0.0 8.9e-08 31.7 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase NMD3 PF04981.13 OAP64826.1 - 2.8e-82 275.9 3.3 3.9e-82 275.4 3.3 1.2 1 0 0 1 1 1 1 NMD3 family DZR PF12773.7 OAP64826.1 - 0.76 9.9 8.1 1.9 8.6 2.5 2.7 1 1 1 2 2 2 0 Double zinc ribbon DUF35_N PF12172.8 OAP64826.1 - 6.6 6.7 7.7 14 5.7 0.1 2.8 3 0 0 3 3 3 0 Rubredoxin-like zinc ribbon domain (DUF35_N) ECH_2 PF16113.5 OAP64827.1 - 1.7e-128 428.8 0.0 2.8e-128 428.1 0.0 1.3 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 OAP64827.1 - 1.8e-27 96.2 0.1 5.3e-27 94.7 0.0 1.7 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase KfrA_N PF11740.8 OAP64827.1 - 0.0091 16.7 1.9 0.13 12.9 0.1 2.8 3 0 0 3 3 3 1 Plasmid replication region DNA-binding N-term MAD PF05557.13 OAP64827.1 - 0.077 11.4 0.3 0.13 10.6 0.3 1.2 1 0 0 1 1 1 0 Mitotic checkpoint protein DASH_Dad3 PF08656.10 OAP64827.1 - 0.11 12.6 1.2 5.1 7.3 0.3 3.2 2 1 0 2 2 2 0 DASH complex subunit Dad3 RRM_1 PF00076.22 OAP64828.1 - 0.00082 19.2 0.0 0.0037 17.0 0.0 2.0 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4195 PF13836.6 OAP64828.1 - 0.1 12.7 7.7 2.4 8.2 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4195) GCIP PF13324.6 OAP64828.1 - 0.14 11.8 3.5 0.2 11.2 3.5 1.3 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting DUF913 PF06025.12 OAP64828.1 - 0.24 10.3 3.9 0.41 9.6 3.9 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) GREB1 PF15782.5 OAP64828.1 - 0.52 7.4 4.5 0.65 7.1 4.5 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer FAM163 PF15069.6 OAP64828.1 - 1.7 9.1 3.2 2.4 8.6 2.6 1.6 1 1 0 1 1 1 0 FAM163 family Hid1 PF12722.7 OAP64828.1 - 4.9 5.2 10.8 7.2 4.6 10.8 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein NOA36 PF06524.12 OAP64828.1 - 6.6 6.0 14.8 12 5.0 14.8 1.5 1 0 0 1 1 1 0 NOA36 protein Glyco_hydro_47 PF01532.20 OAP64829.1 - 2.6e-175 583.8 0.0 2.9e-175 583.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_17 PF00332.18 OAP64830.1 - 1.5e-14 54.4 1.6 2e-14 53.9 1.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 CoaE PF01121.20 OAP64831.1 - 7e-39 133.3 0.0 1e-20 74.2 0.0 2.0 2 0 0 2 2 2 2 Dephospho-CoA kinase AAA_18 PF13238.6 OAP64831.1 - 0.014 16.0 0.1 1.1 9.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain PolyA_pol PF01743.20 OAP64832.1 - 2.9e-24 85.9 1.7 1e-23 84.2 1.7 1.9 1 1 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 OAP64832.1 - 0.0002 21.0 0.0 0.00061 19.5 0.0 1.8 2 0 0 2 2 2 1 Probable RNA and SrmB- binding site of polymerase A Acyl-CoA_dh_1 PF00441.24 OAP64833.1 - 2.9e-28 98.9 0.4 4.1e-28 98.5 0.4 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 OAP64833.1 - 1.1e-25 90.4 0.1 3.7e-25 88.8 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 OAP64833.1 - 1.5e-24 86.0 0.1 2.5e-24 85.3 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 OAP64833.1 - 1.1e-06 28.9 0.1 1.1e-06 28.9 0.1 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Syja_N PF02383.18 OAP64834.1 - 1e-78 264.9 0.2 2.7e-78 263.5 0.2 1.8 1 0 0 1 1 1 1 SacI homology domain Tti2 PF10521.9 OAP64835.1 - 5.4e-56 190.2 1.5 7.5e-56 189.7 1.5 1.2 1 0 0 1 1 1 1 Tti2 family MatE PF01554.18 OAP64836.1 - 2.2e-58 196.5 15.9 8.2e-31 106.8 3.8 2.4 2 1 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 OAP64836.1 - 0.00047 20.2 6.0 0.00047 20.2 6.0 3.7 4 0 0 4 4 4 1 Polysaccharide biosynthesis C-terminal domain Arginase PF00491.21 OAP64837.1 - 1.1e-89 300.7 0.0 1.5e-89 300.3 0.0 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 OAP64837.1 - 0.07 13.4 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 UPF0489 domain Metallophos PF00149.28 OAP64838.1 - 5.4e-38 131.6 0.4 8.6e-38 130.9 0.4 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 OAP64838.1 - 0.094 13.2 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain MmgE_PrpD PF03972.14 OAP64839.1 - 1.9e-95 320.0 0.1 2.2e-95 319.8 0.1 1.0 1 0 0 1 1 1 1 MmgE/PrpD family DUF4387 PF14330.6 OAP64840.1 - 5.3e-35 120.0 0.0 7.4e-35 119.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4387) DUF1890 PF09001.11 OAP64840.1 - 0.03 14.7 0.0 0.042 14.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1890) AtuA PF07287.11 OAP64841.1 - 9.1e-05 21.3 0.0 0.00022 20.0 0.0 1.6 1 1 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA TauD PF02668.16 OAP64842.1 - 1.3e-30 107.1 0.0 1.7e-30 106.8 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 OAP64842.1 - 0.0084 15.3 0.0 0.013 14.7 0.0 1.2 1 0 0 1 1 1 1 CsiD Podoplanin PF05808.11 OAP64844.1 - 0.022 14.8 0.0 0.027 14.6 0.0 1.1 1 0 0 1 1 1 0 Podoplanin Diacid_rec PF05651.13 OAP64844.1 - 0.14 11.8 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Putative sugar diacid recognition TRI12 PF06609.13 OAP64845.1 - 3.3e-14 52.2 7.7 3.8e-14 52.0 7.7 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAP64845.1 - 1.1e-06 27.9 9.2 1.1e-06 27.9 9.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2417 PF10329.9 OAP64845.1 - 0.0029 17.1 2.2 0.0041 16.6 2.2 1.2 1 0 0 1 1 1 1 Region of unknown function (DUF2417) TRI12 PF06609.13 OAP64846.1 - 4.6e-16 58.4 5.4 5.4e-16 58.1 5.4 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 OAP64846.1 - 0.001 18.1 8.5 0.001 18.1 8.5 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily Spore_YtrH PF14034.6 OAP64846.1 - 0.51 10.5 8.5 4.1 7.6 1.8 3.2 3 0 0 3 3 3 0 Sporulation protein YtrH PI31_Prot_N PF11566.8 OAP64847.1 - 8.2e-49 165.5 0.0 1e-48 165.2 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.11 OAP64847.1 - 5.7e-18 65.9 18.3 5.7e-18 65.9 18.3 2.9 3 1 0 3 3 3 1 PI31 proteasome regulator DUF3112 PF11309.8 OAP64848.1 - 0.0038 16.7 2.4 0.0038 16.7 2.4 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF3112) Virul_fac_BrkB PF03631.15 OAP64848.1 - 1.3 8.6 16.2 3.2 7.3 2.8 2.3 1 1 1 2 2 2 0 Virulence factor BrkB DUF4203 PF13886.6 OAP64848.1 - 4.1 7.0 19.5 1.4 8.5 5.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4203) Sad1_UNC PF07738.13 OAP64849.1 - 2.2e-11 43.9 0.0 9.9e-10 38.5 0.0 2.5 1 1 0 1 1 1 1 Sad1 / UNC-like C-terminal SKA1 PF07160.12 OAP64849.1 - 0.016 15.1 4.8 0.53 10.1 0.0 2.2 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 Baculo_PEP_C PF04513.12 OAP64849.1 - 0.68 10.0 5.9 3.2 7.8 0.7 2.4 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1640 PF07798.11 OAP64849.1 - 1.1 9.3 6.7 3 7.9 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) Apolipoprotein PF01442.18 OAP64849.1 - 2.4 8.0 15.4 8.8 6.1 9.6 2.2 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain Ax_dynein_light PF10211.9 OAP64849.1 - 4 7.4 7.2 3.5 7.5 0.3 2.3 2 0 0 2 2 2 0 Axonemal dynein light chain adh_short PF00106.25 OAP64850.1 - 3.1e-31 108.4 0.0 4.7e-31 107.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP64850.1 - 5e-22 78.6 0.0 1e-21 77.6 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 OAP64850.1 - 0.015 14.8 0.1 0.072 12.5 0.0 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OAP64850.1 - 0.066 12.2 0.0 0.097 11.7 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family tRNA_bind PF01588.20 OAP64851.1 - 9.9e-18 64.1 0.1 7.7e-17 61.2 0.1 2.1 1 1 0 1 1 1 1 Putative tRNA binding domain Ndc1_Nup PF09531.10 OAP64851.1 - 4.3 5.9 4.6 4.9 5.7 4.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SNARE PF05739.19 OAP64852.1 - 4.2e-08 33.1 0.3 4.2e-08 33.1 0.3 1.7 2 0 0 2 2 2 1 SNARE domain Use1 PF09753.9 OAP64852.1 - 0.00077 19.3 1.1 0.0012 18.6 1.1 1.3 1 1 0 1 1 1 1 Membrane fusion protein Use1 DUF4407 PF14362.6 OAP64852.1 - 4.1 6.7 9.5 23 4.2 9.5 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) zf-C3HC4 PF00097.25 OAP64853.1 - 1.2e-08 34.6 7.6 1.2e-08 34.6 7.6 3.6 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAP64853.1 - 2.1e-08 34.0 7.1 9.8e-08 31.9 7.1 2.2 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 OAP64853.1 - 2.1e-08 33.9 4.9 2.1e-08 33.9 4.9 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAP64853.1 - 1.3e-07 31.4 7.1 1.3e-07 31.4 7.1 3.3 2 1 1 3 3 3 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 OAP64853.1 - 1.7e-07 31.3 9.6 9.1e-07 28.9 9.6 2.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 OAP64853.1 - 1.3e-06 28.6 8.1 1.3e-06 28.6 8.1 4.4 3 2 1 4 4 4 2 Ring finger domain zf-C3HC4_2 PF13923.6 OAP64853.1 - 2.3e-05 24.1 7.7 2.3e-05 24.1 7.7 4.6 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-TRAF PF02176.18 OAP64853.1 - 4.2e-05 24.1 22.7 0.00052 20.6 5.9 3.5 1 1 3 4 4 4 4 TRAF-type zinc finger zf-RING_4 PF14570.6 OAP64853.1 - 0.019 14.8 1.9 0.019 14.8 1.9 4.4 4 1 1 5 5 5 0 RING/Ubox like zinc-binding domain NPV_P10 PF05531.12 OAP64853.1 - 0.17 12.4 0.6 16 6.0 0.0 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein JAKMIP_CC3 PF16034.5 OAP64853.1 - 0.28 11.1 3.0 0.17 11.8 0.6 1.7 2 0 0 2 2 2 0 JAKMIP CC3 domain Pkip-1 PF06878.11 OAP64853.1 - 0.61 10.2 2.4 1 9.4 0.1 2.1 2 0 0 2 2 2 0 Pkip-1 protein zinc_ribbon_9 PF14369.6 OAP64853.1 - 0.94 9.8 0.1 0.94 9.8 0.1 4.0 3 0 0 3 3 3 0 zinc-ribbon PspA_IM30 PF04012.12 OAP64853.1 - 2.7 7.5 5.9 0.17 11.4 0.3 1.8 2 1 1 3 3 3 0 PspA/IM30 family Pyridox_ox_2 PF12900.7 OAP64854.1 - 5.4e-30 104.2 0.0 1.2e-29 103.1 0.0 1.6 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF4714 PF15833.5 OAP64856.1 - 0.14 12.1 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4714) TFIIA_gamma_C PF02751.14 OAP64857.1 - 1.1e-24 86.2 1.1 1.8e-24 85.6 1.1 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.16 OAP64857.1 - 5.7e-24 83.9 0.1 7.8e-24 83.4 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TTRAP PF14203.6 OAP64858.1 - 0.031 14.3 1.0 0.046 13.7 1.0 1.3 1 0 0 1 1 1 0 Putative tranposon-transfer assisting protein GILT PF03227.16 OAP64859.1 - 1.1e-18 67.4 0.2 2.3e-18 66.4 0.2 1.6 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) Hexokinase_1 PF00349.21 OAP64860.1 - 1.7e-58 197.8 0.0 2.3e-58 197.4 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.16 OAP64860.1 - 3.8e-43 147.7 0.0 7.1e-43 146.7 0.0 1.4 1 1 0 1 1 1 1 Hexokinase AAA_6 PF12774.7 OAP64862.1 - 2.1e-126 421.3 0.0 1.2e-125 418.8 0.0 2.4 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 OAP64862.1 - 5.1e-116 388.1 7.1 5.1e-116 388.1 7.1 4.7 4 1 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 DHC_N1 PF08385.12 OAP64862.1 - 6.5e-115 384.9 8.0 6.5e-115 384.9 8.0 4.4 5 1 0 5 5 5 1 Dynein heavy chain, N-terminal region 1 AAA_9 PF12781.7 OAP64862.1 - 7.8e-73 244.2 0.4 7.8e-73 244.2 0.4 4.2 4 1 0 4 4 4 1 ATP-binding dynein motor region AAA_8 PF12780.7 OAP64862.1 - 2.7e-65 220.3 0.0 6.9e-65 218.9 0.0 1.8 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_7 PF12775.7 OAP64862.1 - 4.5e-41 140.3 0.0 1.1e-35 122.8 0.0 4.6 4 0 0 4 4 4 2 P-loop containing dynein motor region Dynein_heavy PF03028.15 OAP64862.1 - 4.3e-33 113.9 2.1 7.2e-30 103.5 0.0 4.6 4 0 0 4 4 4 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 OAP64862.1 - 4.4e-30 104.9 19.0 4.2e-23 81.9 1.2 2.9 1 1 1 2 2 2 2 Microtubule-binding stalk of dynein motor AAA_5 PF07728.14 OAP64862.1 - 5.4e-28 97.7 1.1 2.4e-10 40.6 0.0 6.9 5 1 0 5 5 5 4 AAA domain (dynein-related subfamily) AAA_lid_11 PF18198.1 OAP64862.1 - 8.9e-28 97.2 0.0 2.4e-27 95.7 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_AAA_lid PF17852.1 OAP64862.1 - 3.7e-18 65.9 0.3 9.7e-16 58.0 0.0 3.3 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA PF00004.29 OAP64862.1 - 6.3e-13 49.3 0.0 0.00032 21.1 0.0 5.0 5 0 0 5 5 4 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OAP64862.1 - 3.6e-12 46.7 1.7 0.062 13.6 0.0 7.0 7 0 0 7 7 5 2 AAA domain AAA_16 PF13191.6 OAP64862.1 - 5.9e-10 39.8 3.7 1.8 8.9 0.0 8.7 7 0 0 7 7 7 1 AAA ATPase domain AAA_33 PF13671.6 OAP64862.1 - 8e-09 35.8 2.9 0.32 11.2 0.0 5.5 5 0 0 5 5 4 3 AAA domain AAA_18 PF13238.6 OAP64862.1 - 1.5e-08 35.2 0.7 0.082 13.5 0.0 6.1 5 0 0 5 5 5 1 AAA domain AAA_lid_1 PF17857.1 OAP64862.1 - 5.5e-06 26.5 0.1 0.0004 20.5 0.0 3.6 3 0 0 3 3 3 1 AAA+ lid domain T2SSE PF00437.20 OAP64862.1 - 6.3e-06 25.4 0.0 0.06 12.4 0.0 3.6 3 0 0 3 3 3 2 Type II/IV secretion system protein ABC_tran PF00005.27 OAP64862.1 - 1.6e-05 25.5 0.1 3 8.3 0.0 5.6 4 0 0 4 4 4 1 ABC transporter FtsK_SpoIIIE PF01580.18 OAP64862.1 - 7.5e-05 22.2 0.0 0.22 10.8 0.0 3.7 3 0 0 3 3 3 1 FtsK/SpoIIIE family AAA_29 PF13555.6 OAP64862.1 - 0.00019 21.1 0.1 0.76 9.6 0.0 3.6 3 0 0 3 3 3 1 P-loop containing region of AAA domain Mg_chelatase PF01078.21 OAP64862.1 - 0.00036 20.0 0.6 0.83 9.0 0.0 3.8 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI BRE1 PF08647.11 OAP64862.1 - 0.00067 19.7 3.5 0.00067 19.7 3.5 4.6 3 0 0 3 3 2 1 BRE1 E3 ubiquitin ligase AAA_19 PF13245.6 OAP64862.1 - 0.00077 19.8 0.2 0.52 10.6 0.0 3.9 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.6 OAP64862.1 - 0.00094 18.8 0.0 0.22 11.1 0.0 3.7 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 OAP64862.1 - 0.006 16.3 0.3 24 4.5 0.0 4.3 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.6 OAP64862.1 - 0.0064 16.2 4.1 37 4.0 0.0 5.7 6 0 0 6 6 6 0 AAA domain IstB_IS21 PF01695.17 OAP64862.1 - 0.012 15.4 0.6 1.1 9.0 0.0 3.9 5 0 0 5 5 3 0 IstB-like ATP binding protein Zeta_toxin PF06414.12 OAP64862.1 - 0.029 13.7 2.8 2.3 7.5 0.0 4.2 5 0 0 5 5 4 0 Zeta toxin FAD-oxidase_C PF02913.19 OAP64862.1 - 0.054 13.1 0.0 0.43 10.2 0.0 2.6 1 0 0 1 1 1 0 FAD linked oxidases, C-terminal domain AAA_28 PF13521.6 OAP64862.1 - 0.057 13.7 0.4 5.3 7.3 0.0 3.8 3 0 0 3 3 3 0 AAA domain PduV-EutP PF10662.9 OAP64862.1 - 0.11 12.3 0.4 4.9 6.9 0.1 3.5 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation TsaE PF02367.17 OAP64862.1 - 0.19 11.7 1.1 14 5.7 0.0 3.8 4 0 0 4 4 4 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sec7 PF01369.20 OAP64863.1 - 4.1e-62 209.1 0.0 6.2e-62 208.5 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 OAP64863.1 - 1.6e-19 70.4 0.0 1.6e-18 67.1 0.0 2.8 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF3696 PF12476.8 OAP64863.1 - 0.11 13.0 0.1 1.7 9.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3696) Ribonuclease_3 PF00636.26 OAP64864.1 - 9.6e-34 116.2 0.0 1.6e-16 60.8 0.0 2.9 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 OAP64864.1 - 5e-19 68.7 0.0 4.3e-07 30.1 0.0 4.1 3 1 0 3 3 3 3 Ribonuclease-III-like ResIII PF04851.15 OAP64864.1 - 1.4e-16 60.9 0.0 2.9e-16 60.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 OAP64864.1 - 2.5e-16 60.0 0.0 6.1e-16 58.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 OAP64864.1 - 1.3e-13 51.1 0.0 2.2e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Dicer_dimer PF03368.14 OAP64864.1 - 1.7e-11 44.1 0.0 7.8e-11 42.0 0.0 2.2 2 0 0 2 2 2 1 Dicer dimerisation domain DUF1476 PF07345.11 OAP64864.1 - 0.0021 18.4 0.1 0.0056 17.0 0.1 1.7 1 0 0 1 1 1 1 ATPase inhibitor subunit zeta AAA_22 PF13401.6 OAP64864.1 - 0.0024 18.1 0.0 0.0074 16.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain ERCC3_RAD25_C PF16203.5 OAP64864.1 - 0.041 13.1 0.0 0.095 11.9 0.0 1.5 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase DUF3391 PF11871.8 OAP64864.1 - 0.081 13.5 0.8 0.23 12.0 0.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) EF-hand_6 PF13405.6 OAP64865.1 - 8.4e-09 34.7 1.0 0.0012 18.6 0.1 2.7 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 OAP64865.1 - 0.00013 22.4 1.4 0.00085 19.7 0.1 2.5 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 OAP64865.1 - 0.0014 18.0 0.0 0.11 12.1 0.0 2.4 2 0 0 2 2 2 2 EF hand Met_10 PF02475.16 OAP64866.1 - 0.00093 19.0 0.0 0.0024 17.7 0.0 1.6 1 1 0 1 1 1 1 Met-10+ like-protein Mannosyl_trans3 PF11051.8 OAP64867.1 - 1.4e-61 208.3 0.0 1e-60 205.5 0.0 2.3 1 1 0 1 1 1 1 Mannosyltransferase putative MFS_1 PF07690.16 OAP64868.1 - 1.3e-25 90.1 42.2 7.9e-19 67.8 12.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Dynamin_N PF00350.23 OAP64869.1 - 5.2e-17 62.4 0.4 2e-16 60.5 0.0 2.2 3 0 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.23 OAP64869.1 - 2e-06 27.9 0.2 6e-05 23.1 0.0 3.0 2 1 0 2 2 2 1 50S ribosome-binding GTPase ABC_tran PF00005.27 OAP64869.1 - 7.3e-05 23.3 0.0 0.00035 21.1 0.0 2.2 2 0 0 2 2 2 1 ABC transporter AIG1 PF04548.16 OAP64869.1 - 0.0011 18.3 0.4 0.028 13.8 0.0 3.0 3 0 0 3 3 3 1 AIG1 family RsgA_GTPase PF03193.16 OAP64869.1 - 0.0038 17.1 1.0 0.02 14.8 0.0 2.6 3 0 0 3 3 3 1 RsgA GTPase FAM184 PF15665.5 OAP64869.1 - 0.0054 16.5 1.3 0.0054 16.5 1.3 2.9 4 0 0 4 4 4 1 Family with sequence similarity 184, A and B AAA_16 PF13191.6 OAP64869.1 - 0.0085 16.5 0.1 0.25 11.7 0.0 3.2 3 0 0 3 3 3 1 AAA ATPase domain Med4 PF10018.9 OAP64869.1 - 0.021 14.5 2.3 0.034 13.8 0.5 2.2 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 AAA_22 PF13401.6 OAP64869.1 - 0.038 14.2 0.4 2.8 8.2 0.0 3.4 3 0 0 3 3 3 0 AAA domain FeoB_N PF02421.18 OAP64869.1 - 0.039 13.5 0.0 2.4 7.7 0.0 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B HCMV_UL139 PF12507.8 OAP64869.1 - 0.077 13.4 4.1 0.059 13.7 1.7 2.0 2 0 0 2 2 2 0 Human Cytomegalovirus UL139 protein AAA_29 PF13555.6 OAP64869.1 - 0.18 11.5 0.0 0.39 10.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 OAP64869.1 - 0.2 12.1 0.0 0.2 12.1 0.0 3.6 3 1 1 4 4 3 0 AAA domain DUF87 PF01935.17 OAP64869.1 - 4.9 7.2 10.0 0.47 10.5 0.1 3.6 3 1 1 4 4 4 0 Helicase HerA, central domain ANAPC4_WD40 PF12894.7 OAP64870.1 - 0.0011 19.2 0.0 0.28 11.5 0.0 3.5 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OAP64870.1 - 0.0015 19.3 0.0 0.039 14.8 0.0 3.1 4 0 0 4 4 4 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 OAP64870.1 - 0.017 14.2 0.0 0.44 9.5 0.0 2.2 2 0 0 2 2 2 0 Coatomer WD associated region MMS1_N PF10433.9 OAP64870.1 - 0.15 10.6 0.0 1.3 7.6 0.0 2.2 3 0 0 3 3 3 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term Mlh1_C PF16413.5 OAP64871.1 - 1.9e-98 329.2 0.0 3.9e-98 328.1 0.0 1.5 2 0 0 2 2 2 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 OAP64871.1 - 2.3e-32 111.2 0.0 4.1e-32 110.4 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 OAP64871.1 - 5.5e-13 48.9 0.0 2.1e-12 47.0 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 OAP64871.1 - 5.8e-08 33.2 0.0 5.4e-06 26.9 0.0 3.1 2 1 1 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Glyco_hydro_cc PF11790.8 OAP64872.1 - 1.1e-40 139.7 1.2 1.9e-40 139.0 1.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core MOR2-PAG1_N PF14222.6 OAP64873.1 - 9.5e-180 599.2 0.3 2.4e-179 597.8 0.0 1.8 2 0 0 2 2 2 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.6 OAP64873.1 - 2.5e-83 279.8 0.1 2.5e-83 279.8 0.1 2.1 2 0 0 2 2 2 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.6 OAP64873.1 - 1.9e-31 108.7 20.5 1.9e-12 45.8 0.6 4.1 1 1 1 3 3 3 3 Cell morphogenesis central region FAD_binding_1 PF00667.20 OAP64874.1 - 3.3e-66 223.0 0.0 4.9e-66 222.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 OAP64874.1 - 9.4e-37 126.4 1.2 1.6e-36 125.7 0.6 1.7 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.21 OAP64874.1 - 2.6e-21 76.3 0.0 2.2e-20 73.3 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Kinetochor_Ybp2 PF08568.10 OAP64875.1 - 2.7e-71 240.9 0.2 5.1e-70 236.7 0.0 2.1 2 0 0 2 2 2 2 Uncharacterised protein family, YAP/Alf4/glomulin DEAD PF00270.29 OAP64877.1 - 1.3e-46 158.6 0.0 2.3e-46 157.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAP64877.1 - 5.8e-23 81.3 0.0 2.8e-22 79.1 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 OAP64877.1 - 6.4e-23 80.7 0.0 1.4e-22 79.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 OAP64877.1 - 3.9e-08 33.5 1.3 6.4e-08 32.8 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DnaJ PF00226.31 OAP64878.1 - 3e-14 52.9 1.5 6.8e-14 51.7 0.3 2.2 2 0 0 2 2 2 1 DnaJ domain VIR_N PF15912.5 OAP64878.1 - 1.3 8.6 4.7 1.8 8.1 4.7 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal DUF3523 PF12037.8 OAP64878.1 - 2.1 7.6 23.5 0.58 9.5 20.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3523) PAPS_reduct PF01507.19 OAP64880.1 - 4.7e-21 75.6 0.0 5.8e-17 62.3 0.0 2.5 2 0 0 2 2 2 2 Phosphoadenosine phosphosulfate reductase family WD40 PF00400.32 OAP64881.1 - 8.6e-122 393.5 51.1 6.1e-11 42.7 0.3 12.1 11 0 0 11 11 11 11 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAP64881.1 - 2.5e-43 146.3 9.7 0.01 16.1 0.0 12.1 2 1 10 12 12 12 11 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OAP64881.1 - 3.2e-42 144.7 15.4 0.0022 17.0 0.0 11.2 1 1 10 11 11 11 11 WD40 region of Ge1, enhancer of mRNA-decapping protein NACHT PF05729.12 OAP64881.1 - 1.3e-21 77.2 0.1 2.7e-21 76.2 0.1 1.5 1 0 0 1 1 1 1 NACHT domain Nup160 PF11715.8 OAP64881.1 - 1.6e-12 46.9 28.1 0.09 11.4 0.2 9.9 1 1 8 9 9 9 5 Nucleoporin Nup120/160 HET PF06985.11 OAP64881.1 - 2.3e-11 44.2 11.3 8.2e-10 39.2 1.9 3.1 2 1 1 3 3 2 2 Heterokaryon incompatibility protein (HET) Frtz PF11768.8 OAP64881.1 - 3.3e-06 25.7 0.3 0.072 11.4 0.0 4.3 1 1 5 6 6 6 1 WD repeat-containing and planar cell polarity effector protein Fritz Nbas_N PF15492.6 OAP64881.1 - 1.5e-05 24.5 25.4 1.8 7.8 0.0 9.9 1 1 9 11 11 11 2 Neuroblastoma-amplified sequence, N terminal DUF2218 PF09981.9 OAP64881.1 - 0.00029 21.2 0.0 52 4.3 0.0 5.6 3 1 3 6 6 6 0 Uncharacterized protein conserved in bacteria (DUF2218) Cytochrom_D1 PF02239.16 OAP64881.1 - 0.00046 18.8 4.5 9.9 4.6 0.1 4.7 3 1 3 6 6 6 2 Cytochrome D1 heme domain DUF5643 PF18705.1 OAP64881.1 - 0.00092 19.2 0.0 1e+02 2.9 0.0 7.2 11 0 0 11 11 10 0 Family of unknown function (DUF5643) BAT PF15915.5 OAP64881.1 - 0.011 15.6 10.7 1.5 8.7 0.1 5.0 2 1 2 6 6 6 0 GAF and HTH_10 associated domain AAA_16 PF13191.6 OAP64881.1 - 0.059 13.7 0.0 0.15 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain DUF2262 PF10020.9 OAP64881.1 - 0.091 13.1 0.2 0.68 10.3 0.1 2.4 3 0 0 3 3 2 0 Uncharacterized protein conserved in bacteria (DUF2262) AAA_19 PF13245.6 OAP64881.1 - 0.12 12.7 0.0 0.28 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain FIT1_2 PF17357.2 OAP64881.1 - 1.6 8.9 16.6 48 4.1 0.2 6.9 2 1 7 9 9 9 0 Facilitor Of iron transport 1 and 2 Glyco_hydro_30C PF17189.4 OAP64881.1 - 9.5 6.5 9.5 3.9e+02 1.4 0.0 6.6 9 0 0 9 9 9 0 Glycosyl hydrolase family 30 beta sandwich domain Polysacc_deac_1 PF01522.21 OAP64882.1 - 7.3e-22 77.6 0.0 1.2e-21 76.9 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 OAP64882.1 - 2.2e-12 47.1 0.1 4.9e-12 45.9 0.1 1.6 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) Glyco_hydro_57 PF03065.15 OAP64882.1 - 0.0017 17.6 0.2 0.0035 16.6 0.2 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 57 2-Hacid_dh_C PF02826.19 OAP64883.1 - 1.8e-37 128.4 0.0 1.2e-36 125.7 0.0 2.0 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 OAP64883.1 - 1.7e-12 47.2 0.0 2.2e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 OAP64883.1 - 0.0027 17.9 0.0 0.0067 16.6 0.0 1.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 OAP64883.1 - 0.06 13.9 0.0 0.11 13.1 0.0 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 OAP64883.1 - 0.19 11.6 0.0 0.3 11.0 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AAT PF03417.16 OAP64884.1 - 8.3e-27 94.3 0.0 1.9e-26 93.2 0.0 1.5 1 1 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Fungal_trans PF04082.18 OAP64885.1 - 1.3e-27 96.5 0.2 2.3e-27 95.7 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP64885.1 - 1.3e-07 31.6 9.6 2.1e-07 30.9 9.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DHDPS PF00701.22 OAP64886.1 - 1.3e-37 129.1 0.0 1.5e-37 128.9 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Peripla_BP_1 PF00532.21 OAP64886.1 - 0.026 13.9 0.0 0.038 13.4 0.0 1.1 1 0 0 1 1 1 0 Periplasmic binding proteins and sugar binding domain of LacI family TPR_10 PF13374.6 OAP64886.1 - 0.05 13.5 1.3 0.59 10.1 0.9 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Aminotran_1_2 PF00155.21 OAP64887.1 - 2.4e-72 244.1 0.0 3.1e-72 243.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Hydantoinase_B PF02538.14 OAP64888.1 - 2.8e-206 685.9 0.4 3.7e-206 685.5 0.4 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 OAP64888.1 - 5.7e-92 308.1 0.0 8.6e-92 307.5 0.0 1.3 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 OAP64888.1 - 2.7e-53 180.3 0.0 2.4e-51 174.0 0.0 2.6 3 0 0 3 3 3 2 Hydantoinase/oxoprolinase N-terminal region MFS_1 PF07690.16 OAP64889.1 - 5.4e-41 140.7 29.0 5.4e-41 140.7 29.0 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Mito_carr PF00153.27 OAP64890.1 - 8.5e-59 195.5 1.2 3.1e-20 71.9 0.0 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 OAP64890.1 - 0.17 11.0 0.0 5.2 6.1 0.0 2.4 2 0 0 2 2 2 0 Gammaproteobacterial serine protease Git3 PF11710.8 OAP64891.1 - 8.3e-61 205.3 18.3 8.3e-61 205.3 18.3 1.4 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 GPR_Gpa2_C PF11970.8 OAP64891.1 - 4.8e-24 84.2 2.5 1.8e-23 82.4 2.5 2.1 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term 7tm_1 PF00001.21 OAP64891.1 - 4.6e-08 32.7 2.7 7.3e-08 32.1 2.7 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) MT-A70 PF05063.14 OAP64892.1 - 3.7e-25 88.8 0.0 5.6e-25 88.2 0.0 1.3 1 0 0 1 1 1 1 MT-A70 Peptidase_C12 PF01088.21 OAP64893.1 - 2.1e-56 191.0 0.0 2.6e-56 190.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Phage_Mu_F PF04233.14 OAP64893.1 - 0.055 14.2 0.0 0.096 13.4 0.0 1.3 1 0 0 1 1 1 0 Phage Mu protein F like protein RsfS PF02410.15 OAP64894.1 - 7.2e-12 45.6 0.0 7.4e-11 42.4 0.0 2.2 1 1 0 1 1 1 1 Ribosomal silencing factor during starvation Pkip-1 PF06878.11 OAP64895.1 - 0.00032 20.9 2.6 0.00057 20.0 2.6 1.3 1 0 0 1 1 1 1 Pkip-1 protein HAP1_N PF04849.13 OAP64895.1 - 0.0048 16.1 8.5 0.0073 15.6 8.5 1.2 1 0 0 1 1 1 1 HAP1 N-terminal conserved region Hamartin PF04388.12 OAP64895.1 - 0.035 12.8 11.2 0.044 12.5 11.2 1.1 1 0 0 1 1 1 0 Hamartin protein FHIPEP PF00771.20 OAP64895.1 - 0.041 12.4 6.0 0.048 12.1 6.0 1.2 1 0 0 1 1 1 0 FHIPEP family Fibin PF15819.5 OAP64895.1 - 0.094 12.5 3.1 0.17 11.6 3.1 1.5 1 0 0 1 1 1 0 Fin bud initiation factor homologue Spc7 PF08317.11 OAP64895.1 - 0.13 11.1 14.4 0.24 10.2 14.4 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein Fez1 PF06818.15 OAP64895.1 - 0.19 12.2 16.8 0.2 12.1 6.2 2.4 1 1 1 2 2 2 0 Fez1 CHAD PF05235.14 OAP64895.1 - 0.32 10.9 10.0 0.52 10.2 10.0 1.4 1 1 0 1 1 1 0 CHAD domain DivIVA PF05103.13 OAP64895.1 - 0.35 11.0 12.1 5.4 7.1 10.1 2.9 2 1 1 3 3 3 0 DivIVA protein FlaC_arch PF05377.11 OAP64895.1 - 0.47 10.9 6.2 0.74 10.3 0.3 3.3 2 1 0 3 3 3 0 Flagella accessory protein C (FlaC) ATG16 PF08614.11 OAP64895.1 - 0.83 9.8 16.0 11 6.2 16.0 2.3 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF745 PF05335.13 OAP64895.1 - 0.84 9.3 7.6 0.14 11.9 1.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF745) BST2 PF16716.5 OAP64895.1 - 2.3 8.9 7.9 0.65 10.6 2.8 2.4 2 1 1 3 3 2 0 Bone marrow stromal antigen 2 ERM PF00769.19 OAP64895.1 - 2.5 7.8 20.2 11 5.8 20.8 1.7 1 1 1 2 2 2 0 Ezrin/radixin/moesin family THOC7 PF05615.13 OAP64895.1 - 2.6 8.3 19.2 0.79 10.0 9.2 2.5 2 1 1 3 3 3 0 Tho complex subunit 7 BRE1 PF08647.11 OAP64895.1 - 6.5 6.9 15.7 1.3 9.2 9.2 2.4 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase Arb2 PF09757.9 OAP64896.1 - 6.1e-84 281.2 0.1 9.7e-84 280.5 0.1 1.3 1 0 0 1 1 1 1 Arb2 domain Hist_deacetyl PF00850.19 OAP64896.1 - 4.3e-82 276.0 0.0 6.4e-82 275.5 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain B-block_TFIIIC PF04182.12 OAP64896.1 - 0.082 13.1 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC Gp_dh_C PF02800.20 OAP64897.1 - 3.6e-72 241.1 0.0 5.1e-72 240.6 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 OAP64897.1 - 2e-38 130.8 0.1 5.2e-38 129.5 0.1 1.7 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 OAP64897.1 - 0.02 15.0 0.1 0.07 13.2 0.0 1.9 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.19 OAP64897.1 - 0.13 11.6 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pho88 PF10032.9 OAP64898.1 - 3.2e-82 274.2 0.0 3.6e-82 274.0 0.0 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) DUF1368 PF07112.11 OAP64898.1 - 0.068 12.0 0.1 0.096 11.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1368) DUF4512 PF14975.6 OAP64898.1 - 0.14 12.9 0.1 0.45 11.3 0.0 1.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4512) NUDIX_2 PF13869.6 OAP64899.1 - 1.6e-79 265.9 0.0 1.9e-79 265.7 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase Peptidase_M16_M PF16187.5 OAP64900.1 - 1.3e-93 313.4 0.7 2.1e-93 312.6 0.7 1.4 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 OAP64900.1 - 3.9e-31 108.0 0.9 1.2e-30 106.5 0.4 2.1 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 OAP64900.1 - 5.5e-31 108.0 1.6 9.1e-19 68.2 0.0 4.2 5 0 0 5 5 5 2 Peptidase M16 inactive domain Abhydrolase_1 PF00561.20 OAP64902.1 - 9.4e-18 64.8 0.0 3.4e-13 49.8 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAP64902.1 - 1.4e-12 47.4 0.0 7.8e-08 31.9 0.0 2.0 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OAP64902.1 - 4.6e-09 37.2 0.0 6e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 OAP64902.1 - 5.8e-05 23.0 0.0 0.13 12.0 0.0 3.0 2 1 0 2 2 2 2 Phospholipase/Carboxylesterase Peptidase_S15 PF02129.18 OAP64902.1 - 0.015 14.9 0.0 0.024 14.2 0.0 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 OAP64902.1 - 0.022 14.2 0.0 1.2 8.6 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family DLH PF01738.18 OAP64902.1 - 0.034 13.7 0.0 0.99 8.9 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family Ndr PF03096.14 OAP64902.1 - 0.077 11.7 0.0 0.24 10.1 0.0 1.8 2 0 0 2 2 2 0 Ndr family DUF3141 PF11339.8 OAP64902.1 - 0.14 10.6 0.0 0.31 9.4 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3141) adh_short PF00106.25 OAP64904.1 - 4.5e-15 55.6 0.0 2.1e-12 46.9 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAP64904.1 - 3.9e-09 36.4 0.0 3.9e-06 26.6 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP64904.1 - 5.6e-09 36.2 0.0 9.4e-09 35.4 0.0 1.4 1 1 0 1 1 1 1 KR domain Ras PF00071.22 OAP64905.1 - 6e-31 107.2 0.1 7.7e-31 106.9 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAP64905.1 - 2e-23 82.9 0.1 3.5e-23 82.1 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAP64905.1 - 1.4e-06 27.9 0.1 2.1e-06 27.3 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OAP64905.1 - 5.1e-05 22.7 0.2 7.2e-05 22.2 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DLIC PF05783.11 OAP64905.1 - 0.00032 19.7 0.5 0.2 10.4 0.0 2.3 2 1 0 2 2 2 2 Dynein light intermediate chain (DLIC) RecA PF00154.21 OAP64905.1 - 0.12 11.9 0.0 4 6.8 0.0 2.1 2 0 0 2 2 2 0 recA bacterial DNA recombination protein Pex14_N PF04695.13 OAP64905.1 - 3.9 8.1 8.2 6.1 7.5 8.2 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF202 PF02656.15 OAP64906.1 - 2.8e-17 62.9 3.3 5e-17 62.1 0.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) TM140 PF14985.6 OAP64906.1 - 0.013 15.0 0.4 0.018 14.6 0.4 1.2 1 0 0 1 1 1 0 TM140 protein family Tetraspanin PF00335.20 OAP64906.1 - 0.017 14.8 1.0 0.048 13.4 0.4 1.8 2 0 0 2 2 2 0 Tetraspanin family DUF4668 PF15701.5 OAP64906.1 - 0.086 12.7 0.5 6.5 6.6 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4668) Yip1 PF04893.17 OAP64906.1 - 0.23 11.2 4.4 0.16 11.7 1.5 1.9 1 1 1 2 2 2 0 Yip1 domain MatE PF01554.18 OAP64907.1 - 1.2e-57 194.1 28.1 1.1e-33 116.2 11.4 2.3 2 0 0 2 2 2 2 MatE NUDIX PF00293.28 OAP64908.1 - 2.9e-24 85.6 0.0 4.1e-24 85.1 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain IPK PF03770.16 OAP64910.1 - 1.8e-55 187.9 0.0 2.9e-55 187.2 0.0 1.3 1 0 0 1 1 1 1 Inositol polyphosphate kinase Pam17 PF08566.10 OAP64910.1 - 0.043 13.7 0.0 0.085 12.7 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial import protein Pam17 Cu-oxidase_3 PF07732.15 OAP64912.1 - 1.4e-37 128.3 2.1 3.9e-37 126.9 2.1 1.8 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 OAP64912.1 - 3e-30 104.8 0.4 3e-30 104.8 0.4 3.1 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.22 OAP64912.1 - 1e-22 81.0 1.5 1.4e-22 80.6 0.2 1.9 2 0 0 2 2 2 1 Multicopper oxidase DUF2812 PF11193.8 OAP64912.1 - 0.072 13.3 0.1 0.15 12.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2812) Pmp3 PF01679.17 OAP64914.1 - 8.3e-20 70.7 9.5 1.1e-19 70.4 9.5 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator PEX11 PF05648.14 OAP64915.1 - 1.3e-07 31.3 0.1 9.5e-07 28.5 0.1 2.3 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Fungal_trans PF04082.18 OAP64916.1 - 9.4e-21 74.0 0.2 2.4e-20 72.7 0.2 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain NmrA PF05368.13 OAP64917.1 - 6.7e-16 58.5 0.0 9.9e-16 58.0 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAP64917.1 - 4.9e-10 39.6 0.0 8.2e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAP64917.1 - 3.2e-05 23.5 0.0 7e-05 22.4 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAP64917.1 - 0.0028 17.1 0.0 0.0048 16.3 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Semialdhyde_dh PF01118.24 OAP64917.1 - 0.0076 16.7 0.0 0.015 15.8 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.17 OAP64917.1 - 0.11 11.6 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain Amidohydro_1 PF01979.20 OAP64918.1 - 1e-29 104.0 0.1 2.4e-28 99.4 0.1 2.0 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 OAP64918.1 - 1.9e-14 54.0 1.7 2.5e-07 30.6 0.2 2.4 1 1 0 2 2 2 2 Amidohydrolase family Glutaminase PF04960.15 OAP64919.1 - 3.7e-113 377.4 0.4 4.6e-113 377.2 0.4 1.1 1 0 0 1 1 1 1 Glutaminase STAS PF01740.21 OAP64919.1 - 0.017 14.7 0.0 0.033 13.8 0.0 1.4 1 0 0 1 1 1 0 STAS domain PIR PF00399.19 OAP64920.1 - 5.5e-08 32.2 19.6 0.00018 21.0 5.3 2.9 2 0 0 2 2 2 2 Yeast PIR protein repeat LRR_4 PF12799.7 OAP64921.1 - 6.1e-34 115.5 35.0 1.2e-06 28.7 0.4 8.7 6 2 2 8 8 8 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OAP64921.1 - 2.9e-27 94.2 29.3 1.8e-08 34.0 1.5 7.1 4 2 1 6 6 6 6 Leucine rich repeat LRR_6 PF13516.6 OAP64921.1 - 2.7e-08 33.2 32.8 0.32 11.1 0.0 11.1 12 1 1 13 13 13 4 Leucine Rich repeat LRR_9 PF14580.6 OAP64921.1 - 4.5e-08 32.8 14.3 0.025 14.1 2.3 5.0 1 1 3 5 5 5 4 Leucine-rich repeat LRR_1 PF00560.33 OAP64921.1 - 8e-06 25.7 28.0 9.1 7.3 0.0 10.8 8 3 1 9 9 9 4 Leucine Rich Repeat Mito_carr PF00153.27 OAP64922.1 - 3.7e-48 161.4 1.1 2e-21 75.7 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3337 PF11816.8 OAP64923.1 - 4.7e-58 195.8 0.0 1.1e-57 194.7 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3337) WD40 PF00400.32 OAP64923.1 - 5.1e-18 65.1 20.4 3.9e-05 24.3 0.4 6.6 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAP64923.1 - 1e-05 25.7 0.3 0.0097 16.2 0.1 3.6 2 2 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OAP64923.1 - 0.042 12.5 0.9 0.12 11.0 0.1 2.0 2 0 0 2 2 2 0 Nucleoporin Nup120/160 DUF5476 PF17570.2 OAP64923.1 - 0.053 13.9 1.5 0.18 12.2 1.5 2.0 1 0 0 1 1 1 0 Family of unknown function (DUF5476) Ge1_WD40 PF16529.5 OAP64923.1 - 0.1 11.6 0.3 0.48 9.3 0.0 1.9 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_3 PF13570.6 OAP64923.1 - 1.3 9.6 3.7 3.2 8.4 0.1 3.4 4 0 0 4 4 4 0 PQQ-like domain FAM220 PF15487.6 OAP64923.1 - 1.5 8.4 4.5 4.6 6.8 4.5 1.8 1 1 0 1 1 1 0 FAM220 family Pkinase PF00069.25 OAP64924.1 - 8.6e-49 166.3 0.0 2.1e-48 165.0 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP64924.1 - 4.1e-23 82.0 0.0 8.4e-23 81.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAP64924.1 - 0.009 15.4 0.0 0.026 13.9 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 OAP64924.1 - 0.011 15.6 0.0 0.022 14.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OAP64924.1 - 0.027 13.4 0.0 0.044 12.7 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain PIP49_C PF12260.8 OAP64924.1 - 0.2 11.3 0.0 0.36 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 DUF2781 PF10914.8 OAP64924.1 - 0.22 11.9 0.0 0.33 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2781) Ribosomal_L11 PF00298.19 OAP64925.1 - 1.8e-28 98.8 0.1 2.9e-28 98.1 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.14 OAP64925.1 - 2.5e-26 91.3 0.3 3.5e-26 90.8 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Svf1 PF08622.10 OAP64926.1 - 4.1e-55 186.3 0.1 5.7e-55 185.8 0.1 1.2 1 0 0 1 1 1 1 Svf1-like N-terminal lipocalin domain Svf1_C PF17187.4 OAP64926.1 - 5.1e-47 159.8 0.0 1.2e-46 158.5 0.0 1.6 2 0 0 2 2 2 1 Svf1-like C-terminal lipocalin-like domain ADH_zinc_N PF00107.26 OAP64927.1 - 1.3e-26 93.1 0.1 2e-26 92.5 0.1 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAP64927.1 - 2.1e-19 70.9 0.0 4e-19 70.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAP64927.1 - 8.9e-06 25.6 0.0 9e-05 22.3 0.0 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 OAP64927.1 - 0.00099 19.0 0.0 0.0019 18.1 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase adh_short PF00106.25 OAP64927.1 - 0.065 12.7 0.1 0.095 12.1 0.1 1.3 1 0 0 1 1 1 0 short chain dehydrogenase HTH_Tnp_Tc3_1 PF11427.8 OAP64928.1 - 1.5 8.7 4.2 0.87 9.5 0.8 2.1 1 1 1 2 2 2 0 Tc3 transposase ATP-synt_C PF00137.21 OAP64929.1 - 2.9e-24 85.2 35.9 2.9e-15 56.3 10.8 2.7 3 0 0 3 3 3 2 ATP synthase subunit C SLATT_5 PF18160.1 OAP64929.1 - 0.12 11.6 3.6 0.15 11.4 0.0 2.1 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 Oxidored_q2 PF00420.24 OAP64929.1 - 3.4 7.4 8.0 2.5 7.8 4.4 2.7 2 1 1 3 3 3 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L DDHD PF02862.17 OAP64930.1 - 1e-22 81.5 1.8 1.5e-20 74.3 0.0 3.1 3 1 0 3 3 3 1 DDHD domain MoCF_biosynth PF00994.24 OAP64931.1 - 6.2e-46 155.6 0.1 8.6e-23 80.6 0.0 2.4 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.17 OAP64931.1 - 3e-37 127.8 3.3 4.5e-37 127.2 3.3 1.3 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.15 OAP64931.1 - 9.8e-16 57.7 0.1 2.4e-15 56.5 0.1 1.7 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) Tannase PF07519.11 OAP64932.1 - 4e-95 319.4 0.0 7.9e-95 318.5 0.0 1.4 2 0 0 2 2 2 1 Tannase and feruloyl esterase Hydrolase_4 PF12146.8 OAP64932.1 - 0.0046 16.3 0.0 0.04 13.2 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 OAP64932.1 - 0.025 14.1 0.0 4.7 6.6 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family RNA_pol PF00940.19 OAP64933.1 - 7.1e-182 604.8 0.0 1.5e-181 603.8 0.0 1.5 1 1 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 OAP64933.1 - 2.6e-85 286.8 0.0 6.5e-85 285.5 0.0 1.7 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal GFO_IDH_MocA PF01408.22 OAP64934.1 - 7e-20 72.0 0.1 1.6e-19 70.9 0.1 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 OAP64934.1 - 0.0002 22.0 0.2 0.01 16.5 0.0 2.3 2 0 0 2 2 2 1 Homoserine dehydrogenase, NAD binding domain IlvC PF01450.19 OAP64934.1 - 0.014 15.7 0.1 0.026 14.8 0.1 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain Sin_N PF04801.13 OAP64935.1 - 3.2e-23 82.6 0.0 5.9e-23 81.8 0.0 1.3 1 1 0 1 1 1 1 Sin-like protein conserved region AT_hook PF02178.19 OAP64935.1 - 0.35 10.9 8.5 1.6 8.9 8.5 2.2 1 0 0 1 1 1 0 AT hook motif NIR_SIR PF01077.22 OAP64936.1 - 2.6e-48 163.5 0.0 1.7e-44 151.2 0.0 2.4 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 OAP64936.1 - 6.3e-31 106.0 0.0 2e-14 53.2 0.0 2.7 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.25 OAP64936.1 - 2.4e-29 102.4 0.0 5.4e-29 101.2 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin POR_N PF01855.19 OAP64936.1 - 3.6e-07 30.2 0.4 8.9e-07 28.9 0.0 1.8 2 0 0 2 2 2 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Methyltransf_11 PF08241.12 OAP64937.1 - 2.1e-18 66.8 0.2 1.4e-16 60.9 0.2 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAP64937.1 - 4.1e-17 62.7 0.3 2.8e-07 31.1 0.1 2.4 1 1 1 2 2 2 2 Methyltransferase domain CMAS PF02353.20 OAP64937.1 - 1.5e-16 60.5 0.0 5.5e-16 58.7 0.0 1.7 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 OAP64937.1 - 1.6e-15 57.4 0.0 2.3e-15 56.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAP64937.1 - 1.4e-13 51.4 0.0 2.4e-12 47.5 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAP64937.1 - 1.4e-12 47.7 0.0 1.7e-05 24.7 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Ubie_methyltran PF01209.18 OAP64937.1 - 1.8e-06 27.5 0.0 9.2e-05 21.9 0.0 2.2 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MetW PF07021.12 OAP64937.1 - 0.00027 20.6 0.0 0.0096 15.5 0.1 2.4 3 0 0 3 3 3 1 Methionine biosynthesis protein MetW MTS PF05175.14 OAP64937.1 - 0.00048 19.7 0.0 0.0036 16.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase small domain DOT1 PF08123.13 OAP64937.1 - 0.0021 17.6 0.0 0.0043 16.6 0.0 1.5 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_PK PF05891.12 OAP64937.1 - 0.0075 15.8 0.0 1.2 8.6 0.0 2.2 2 0 0 2 2 2 1 AdoMet dependent proline di-methyltransferase Methyltransf_32 PF13679.6 OAP64937.1 - 0.017 15.1 0.0 0.026 14.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.20 OAP64937.1 - 0.019 14.1 0.0 0.028 13.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase PCMT PF01135.19 OAP64937.1 - 0.061 13.1 0.0 0.091 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) ADH_zinc_N PF00107.26 OAP64937.1 - 0.064 13.2 0.0 0.24 11.4 0.0 2.0 3 0 0 3 3 3 0 Zinc-binding dehydrogenase Caleosin PF05042.13 OAP64938.1 - 1.5e-63 213.8 0.3 1.8e-63 213.5 0.3 1.1 1 0 0 1 1 1 1 Caleosin related protein EF-hand_6 PF13405.6 OAP64938.1 - 0.0014 18.4 0.1 0.84 9.7 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain p450 PF00067.22 OAP64939.1 - 1.1e-44 153.0 0.0 1.5e-44 152.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Reticulon PF02453.17 OAP64939.1 - 0.018 15.0 0.0 0.032 14.2 0.0 1.4 1 0 0 1 1 1 0 Reticulon Methyltransf_23 PF13489.6 OAP64940.1 - 1.1e-11 44.8 0.0 5.3e-11 42.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAP64940.1 - 0.0035 17.1 0.0 0.011 15.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAP64940.1 - 0.0057 17.3 0.0 0.013 16.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAP64940.1 - 0.027 15.1 0.0 0.059 14.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 OAP64940.1 - 0.027 15.2 0.0 0.081 13.7 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain RicinB_lectin_2 PF14200.6 OAP64940.1 - 0.073 13.8 1.1 1.2 10.0 0.0 2.8 2 0 0 2 2 2 0 Ricin-type beta-trefoil lectin domain-like Nitroreductase PF00881.24 OAP64941.1 - 1.9e-12 47.6 0.2 4e-12 46.5 0.2 1.6 1 1 0 1 1 1 1 Nitroreductase family FAD_binding_3 PF01494.19 OAP64943.1 - 3.6e-20 72.5 0.0 5.1e-20 72.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAP64943.1 - 3.3e-09 36.8 2.8 0.00024 20.8 1.8 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAP64943.1 - 4e-08 32.9 0.4 1.9e-07 30.6 0.2 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAP64943.1 - 3.6e-07 30.3 0.7 9.1e-07 29.0 0.7 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 OAP64943.1 - 1.7e-05 24.4 0.8 0.11 11.8 0.2 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase SE PF08491.10 OAP64943.1 - 0.00017 20.8 0.0 0.0005 19.2 0.0 1.6 2 0 0 2 2 2 1 Squalene epoxidase GIDA PF01134.22 OAP64943.1 - 0.00019 20.6 3.1 0.00074 18.7 1.9 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A Trp_halogenase PF04820.14 OAP64943.1 - 0.00027 19.9 0.9 0.18 10.6 0.6 2.3 2 0 0 2 2 2 2 Tryptophan halogenase FAD_oxidored PF12831.7 OAP64943.1 - 0.00054 19.4 0.1 0.00073 19.0 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OAP64943.1 - 0.00055 19.1 3.1 0.00058 19.1 1.8 1.6 2 0 0 2 2 2 1 FAD binding domain Rossmann-like PF10727.9 OAP64943.1 - 0.0022 17.9 0.3 0.0051 16.7 0.3 1.6 1 0 0 1 1 1 1 Rossmann-like domain HI0933_like PF03486.14 OAP64943.1 - 0.0022 16.8 2.1 0.0042 15.8 0.7 1.8 2 0 0 2 2 2 1 HI0933-like protein AlaDh_PNT_C PF01262.21 OAP64943.1 - 0.027 13.8 0.2 0.055 12.8 0.2 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 OAP64943.1 - 0.051 13.5 0.1 0.086 12.7 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.27 OAP64943.1 - 0.068 13.7 0.3 0.25 11.9 0.5 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAP64943.1 - 0.098 11.9 0.3 0.19 11.0 0.3 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAP64943.1 - 0.15 12.0 2.0 2.2 8.3 0.2 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding ApbA PF02558.16 OAP64943.1 - 0.16 11.6 0.5 0.26 10.9 0.5 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA ABC2_membrane PF01061.24 OAP64944.1 - 2.8e-76 255.6 72.9 9e-41 139.6 26.7 3.7 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 OAP64944.1 - 2.7e-37 128.3 0.0 2.6e-18 66.9 0.0 2.7 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.12 OAP64944.1 - 2.1e-28 98.0 2.8 5.5e-26 90.3 0.3 4.1 5 0 0 5 5 4 2 CDR ABC transporter ABC_trans_N PF14510.6 OAP64944.1 - 2.1e-11 44.3 0.0 2.1e-11 44.3 0.0 2.3 3 0 0 3 3 2 1 ABC-transporter N-terminal AAA_25 PF13481.6 OAP64944.1 - 6.2e-06 25.9 0.0 0.00021 20.9 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 OAP64944.1 - 2.1e-05 24.1 1.1 0.0011 18.7 0.4 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.6 OAP64944.1 - 4.2e-05 24.0 0.2 0.0085 16.5 0.0 2.9 3 0 0 3 3 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 OAP64944.1 - 4.3e-05 23.5 0.0 0.0018 18.2 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase ABC2_membrane_3 PF12698.7 OAP64944.1 - 7.5e-05 22.0 12.1 7.5e-05 22.0 12.1 3.6 3 2 0 4 4 4 1 ABC-2 family transporter protein AAA_33 PF13671.6 OAP64944.1 - 9e-05 22.7 1.2 0.029 14.5 0.1 2.7 3 0 0 3 3 2 1 AAA domain AAA_18 PF13238.6 OAP64944.1 - 0.00018 22.1 0.3 0.00071 20.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 OAP64944.1 - 0.00043 20.2 0.1 0.35 10.6 0.0 3.4 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OAP64944.1 - 0.0013 18.3 0.1 0.017 14.6 0.0 2.6 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain NACHT PF05729.12 OAP64944.1 - 0.0019 18.2 1.1 1.1 9.2 0.2 3.0 3 0 0 3 3 3 1 NACHT domain Pax2_C PF12403.8 OAP64944.1 - 0.0033 17.5 2.3 0.036 14.1 0.1 2.5 2 0 0 2 2 2 1 Paired-box protein 2 C terminal AAA_23 PF13476.6 OAP64944.1 - 0.0037 17.8 0.9 0.02 15.4 0.0 2.5 3 0 0 3 3 2 1 AAA domain cobW PF02492.19 OAP64944.1 - 0.0051 16.4 0.7 0.065 12.8 0.1 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.6 OAP64944.1 - 0.0052 17.2 0.6 0.14 12.6 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 OAP64944.1 - 0.011 16.0 1.2 0.15 12.3 0.2 2.8 2 1 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 OAP64944.1 - 0.013 15.6 0.3 3.7 7.7 0.1 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_28 PF13521.6 OAP64944.1 - 0.032 14.5 0.3 0.032 14.5 0.3 1.8 2 0 0 2 2 1 0 AAA domain RNA_helicase PF00910.22 OAP64944.1 - 0.045 14.1 0.0 14 6.1 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA PF00004.29 OAP64944.1 - 0.06 13.8 0.1 1.8 9.0 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 OAP64944.1 - 0.073 12.8 0.4 2.5 7.8 0.5 2.4 2 0 0 2 2 2 0 AAA domain CLP1_P PF16575.5 OAP64945.1 - 1e-31 110.2 0.0 2.8e-26 92.5 0.0 2.6 1 1 1 2 2 2 2 mRNA cleavage and polyadenylation factor CLP1 P-loop CLP1_N PF16573.5 OAP64945.1 - 9.6e-29 99.5 0.1 7.9e-28 96.5 0.1 2.4 2 1 0 2 2 2 1 N-terminal beta-sandwich domain of polyadenylation factor Clp1 PF06807.14 OAP64945.1 - 1.6e-25 89.8 0.0 2.9e-25 89.0 0.0 1.4 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 ATP_bind_1 PF03029.17 OAP64945.1 - 0.0023 17.8 0.0 0.0069 16.2 0.0 1.7 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 OAP64945.1 - 0.026 14.6 0.0 0.12 12.5 0.0 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_24 PF13479.6 OAP64945.1 - 0.046 13.5 0.0 0.071 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 OAP64945.1 - 0.052 14.1 0.0 0.12 12.9 0.0 1.6 1 0 0 1 1 1 0 ABC transporter SRPRB PF09439.10 OAP64945.1 - 0.16 11.4 0.0 0.29 10.6 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_35 PF14516.6 OAP64945.1 - 0.17 10.7 0.0 0.26 10.1 0.0 1.1 1 0 0 1 1 1 0 AAA-like domain IPK PF03770.16 OAP64946.1 - 2.8e-53 180.7 0.0 1.1e-52 178.7 0.0 1.9 1 1 0 1 1 1 1 Inositol polyphosphate kinase Use1 PF09753.9 OAP64946.1 - 0.042 13.6 0.9 0.061 13.0 0.9 1.2 1 0 0 1 1 1 0 Membrane fusion protein Use1 RNA_pol_3_Rpc31 PF11705.8 OAP64946.1 - 0.13 12.5 7.6 0.22 11.8 7.6 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DUF2457 PF10446.9 OAP64946.1 - 0.17 11.0 8.6 0.26 10.4 8.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RXT2_N PF08595.11 OAP64946.1 - 0.3 11.1 4.0 0.52 10.3 4.0 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal PBP1_TM PF14812.6 OAP64946.1 - 3.3 8.2 8.7 2.6 8.5 6.8 1.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Astro_capsid_p PF12226.8 OAP64946.1 - 5.6 6.0 8.6 8.2 5.5 8.6 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Arb1 PF09692.10 OAP64947.1 - 2.3e-118 395.9 0.0 3e-118 395.5 0.0 1.1 1 0 0 1 1 1 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 Apt1 PF10351.9 OAP64948.1 - 2.6e-197 656.4 5.2 2.6e-197 656.4 5.2 3.0 3 0 0 3 3 3 1 Golgi-body localisation protein domain Fmp27 PF10344.9 OAP64948.1 - 3.8e-187 624.2 0.0 7e-187 623.3 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial protein from FMP27 Fmp27_WPPW PF10359.9 OAP64948.1 - 3.1e-177 590.3 0.3 3.1e-177 590.3 0.3 3.0 4 0 0 4 4 4 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.9 OAP64948.1 - 1.4e-56 190.7 0.7 4e-56 189.2 0.7 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_GFWDK PF10347.9 OAP64948.1 - 6.8e-53 179.0 0.1 2.1e-52 177.4 0.0 1.9 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain Fmp27_SW PF10305.9 OAP64948.1 - 3.6e-34 117.5 0.4 5.9e-33 113.6 0.0 3.4 3 0 0 3 3 3 1 RNA pol II promoter Fmp27 protein domain GPS2_interact PF15784.5 OAP64949.1 - 0.076 13.5 0.1 0.1 13.0 0.1 1.2 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain RRM_1 PF00076.22 OAP64950.1 - 1.4e-11 44.0 0.0 2.7e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) B-block_TFIIIC PF04182.12 OAP64951.1 - 4.9e-19 68.3 0.0 4e-17 62.1 0.0 3.0 2 0 0 2 2 2 1 B-block binding subunit of TFIIIC MarR_2 PF12802.7 OAP64951.1 - 7.2e-05 22.6 0.8 0.25 11.2 0.0 3.7 4 0 0 4 4 4 2 MarR family MarR PF01047.22 OAP64951.1 - 0.00083 19.2 0.4 1.2 9.1 0.2 3.0 2 0 0 2 2 2 2 MarR family Fe_dep_repress PF01325.19 OAP64951.1 - 0.051 13.8 0.0 0.19 11.9 0.0 2.0 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain HTH_24 PF13412.6 OAP64951.1 - 0.072 12.7 3.5 0.74 9.4 0.4 3.2 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding MMS1_N PF10433.9 OAP64952.1 - 2.6e-119 399.1 0.0 5.6e-119 398.0 0.0 1.5 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 OAP64952.1 - 2.1e-51 175.1 0.0 6.3e-51 173.6 0.0 1.8 2 0 0 2 2 2 1 CPSF A subunit region Ferric_reduct PF01794.19 OAP64954.1 - 2e-20 73.2 9.4 2e-20 73.2 9.4 2.6 3 0 0 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 OAP64954.1 - 0.0025 17.9 0.8 2 8.5 0.5 2.7 2 1 1 3 3 3 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 OAP64954.1 - 0.0045 17.0 0.2 0.017 15.2 0.3 2.0 2 1 0 2 2 2 1 FAD-binding domain NAD_binding_1 PF00175.21 OAP64954.1 - 0.17 12.5 0.2 6 7.6 0.2 2.6 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain WD40 PF00400.32 OAP64957.1 - 2e-29 101.2 12.1 5.5e-07 30.2 0.8 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.8 OAP64957.1 - 7.3e-09 34.8 4.3 0.041 12.5 0.3 5.1 4 1 1 5 5 5 3 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 OAP64957.1 - 3.1e-06 27.4 0.0 0.14 12.5 0.0 4.6 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain APG6_N PF17675.1 OAP64957.1 - 0.0049 17.4 6.4 0.01 16.4 6.4 1.4 1 0 0 1 1 1 1 Apg6 coiled-coil region Uds1 PF15456.6 OAP64957.1 - 0.0082 16.3 4.0 0.03 14.5 4.0 1.9 1 0 0 1 1 1 1 Up-regulated During Septation EzrA PF06160.12 OAP64957.1 - 0.0087 14.3 5.0 0.013 13.7 5.0 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA THOC7 PF05615.13 OAP64957.1 - 0.022 15.0 3.4 0.042 14.1 3.4 1.4 1 0 0 1 1 1 0 Tho complex subunit 7 DUF4482 PF14818.6 OAP64957.1 - 0.045 14.6 2.2 0.11 13.3 2.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4482) AAA_23 PF13476.6 OAP64957.1 - 0.3 11.6 1.8 0.47 10.9 1.8 1.2 1 0 0 1 1 1 0 AAA domain DUF724 PF05266.14 OAP64957.1 - 0.33 10.8 4.9 0.72 9.6 4.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF848 PF05852.11 OAP64957.1 - 0.85 9.7 4.7 2 8.5 4.7 1.6 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) FapA PF03961.13 OAP64957.1 - 1.1 7.8 4.9 1.6 7.3 4.9 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A TMPIT PF07851.13 OAP64957.1 - 2.1 7.5 3.4 3.2 6.9 3.4 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF1664 PF07889.12 OAP64957.1 - 5.5 7.1 5.8 11 6.1 5.1 2.0 2 0 0 2 2 1 0 Protein of unknown function (DUF1664) TUG-UBL1 PF11470.8 OAP64958.1 - 0.14 12.4 0.0 0.44 10.8 0.0 1.8 2 0 0 2 2 2 0 TUG ubiquitin-like domain BCIP PF13862.6 OAP64959.1 - 2.8e-74 249.4 0.0 3.6e-74 249.0 0.0 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein GATase PF00117.28 OAP64960.1 - 1.2e-39 136.1 0.0 1.9e-39 135.4 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.22 OAP64960.1 - 1.8e-39 133.7 0.0 3.4e-39 132.8 0.0 1.5 1 0 0 1 1 1 1 GMP synthase C terminal domain NAD_synthase PF02540.17 OAP64960.1 - 2.7e-11 43.1 0.1 6.1e-07 28.8 0.1 2.3 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 OAP64960.1 - 8.4e-07 29.0 0.0 1.7e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 QueC PF06508.13 OAP64960.1 - 0.0026 17.3 0.0 0.015 14.8 0.0 1.9 1 1 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 OAP64960.1 - 0.0035 16.2 0.1 0.0092 14.8 0.1 1.7 2 0 0 2 2 2 1 tRNA methyl transferase ThiI PF02568.14 OAP64960.1 - 0.012 15.2 0.0 0.035 13.7 0.0 1.7 2 0 0 2 2 2 0 Thiamine biosynthesis protein (ThiI) PAPS_reduct PF01507.19 OAP64960.1 - 0.032 14.3 0.0 0.05 13.6 0.0 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family Arginosuc_synth PF00764.19 OAP64960.1 - 0.095 12.0 0.1 0.15 11.3 0.1 1.2 1 0 0 1 1 1 0 Arginosuccinate synthase ATP_bind_3 PF01171.20 OAP64960.1 - 0.2 11.4 0.0 0.33 10.7 0.0 1.3 1 0 0 1 1 1 0 PP-loop family TauD PF02668.16 OAP64961.1 - 0.00026 20.9 0.1 0.00042 20.2 0.0 1.3 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF2183 PF09949.9 OAP64963.1 - 8.9e-33 112.6 0.0 2e-32 111.4 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) CarboxypepD_reg PF13620.6 OAP64963.1 - 0.001 19.3 0.1 0.0093 16.2 0.0 2.4 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain LNS2 PF08235.13 OAP64963.1 - 0.032 13.7 0.0 0.052 13.0 0.0 1.2 1 0 0 1 1 1 0 LNS2 (Lipin/Ned1/Smp2) WD40 PF00400.32 OAP64966.1 - 0.00018 22.3 8.7 10 7.2 1.7 6.4 6 1 0 6 6 6 3 WD domain, G-beta repeat INTS5_N PF14837.6 OAP64967.1 - 0.054 13.1 0.0 0.094 12.3 0.0 1.4 1 0 0 1 1 1 0 Integrator complex subunit 5 N-terminus TPR_1 PF00515.28 OAP64968.1 - 7e-10 38.3 0.6 0.002 17.9 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 OAP64968.1 - 3.2e-07 30.0 0.3 0.025 14.7 0.1 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 OAP64968.1 - 4.1e-07 29.6 0.6 0.037 14.1 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 OAP64968.1 - 3.2e-05 24.1 0.7 0.00013 22.2 0.7 1.9 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.6 OAP64968.1 - 8.5e-05 23.0 0.3 0.00022 21.6 0.3 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.6 OAP64968.1 - 0.0024 17.5 0.2 0.0076 15.9 0.1 1.9 2 0 0 2 2 2 1 TPR repeat TPR_14 PF13428.6 OAP64968.1 - 0.003 18.3 0.3 0.27 12.1 0.2 2.7 1 1 1 2 2 2 1 Tetratricopeptide repeat BUD22 PF09073.10 OAP64968.1 - 0.003 17.0 8.4 0.0058 16.0 8.4 1.4 1 0 0 1 1 1 1 BUD22 ANAPC3 PF12895.7 OAP64968.1 - 0.025 14.8 2.0 0.12 12.7 2.0 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 OAP64968.1 - 0.12 13.1 0.2 13 6.7 0.2 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat AP3D1 PF06375.11 OAP64968.1 - 0.37 11.0 5.8 0.091 13.0 2.4 1.7 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 ATP-synt_DE PF00401.20 OAP64968.1 - 1.5 9.1 4.8 4 7.8 1.5 2.6 2 0 0 2 2 2 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain Striatin PF08232.12 OAP64968.1 - 4.7 7.8 8.7 80 3.8 8.7 2.4 1 1 0 1 1 1 0 Striatin family HAD_2 PF13419.6 OAP64969.1 - 2.3e-16 60.4 0.0 1.7e-07 31.5 0.0 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OAP64969.1 - 9.1e-08 32.6 0.0 6.6e-06 26.6 0.0 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OAP64969.1 - 0.00089 19.3 0.0 0.0025 17.8 0.0 1.9 1 1 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 OAP64969.1 - 0.14 12.3 0.0 14 5.9 0.0 2.3 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase PQ-loop PF04193.14 OAP64970.1 - 1e-22 79.6 13.7 1.5e-11 43.9 2.6 2.8 2 1 0 2 2 2 2 PQ loop repeat DUF4381 PF14316.6 OAP64970.1 - 0.18 12.0 0.9 11 6.2 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4381) SLATT_fungal PF18142.1 OAP64970.1 - 0.2 11.7 1.5 0.55 10.2 1.5 1.7 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain Fungal_trans_2 PF11951.8 OAP64971.1 - 3.8e-12 45.7 0.1 3.3e-11 42.6 0.1 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP64972.1 - 1e-09 38.3 10.3 1.7e-09 37.6 10.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2236 PF09995.9 OAP64973.1 - 7.4e-08 32.9 0.5 1.1e-07 32.3 0.5 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) Oxysterol_BP PF01237.18 OAP64975.1 - 1.5e-55 188.6 0.7 2.9e-53 181.1 0.7 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein FAD_binding_4 PF01565.23 OAP64977.1 - 2.1e-14 53.4 0.0 4.6e-14 52.3 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Aldedh PF00171.22 OAP64978.1 - 4.2e-149 497.0 0.1 5.3e-149 496.7 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 OAP64978.1 - 0.17 10.9 0.1 0.28 10.2 0.1 1.2 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) SnoaL_2 PF12680.7 OAP64979.1 - 2.7e-05 24.7 0.1 5.5e-05 23.7 0.0 1.6 1 1 0 1 1 1 1 SnoaL-like domain MFS_1 PF07690.16 OAP64980.1 - 7e-34 117.3 39.9 7e-34 117.3 39.9 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 OAP64980.1 - 0.017 13.5 3.1 0.027 12.9 3.1 1.2 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) bZIP_2 PF07716.15 OAP64981.1 - 0.041 14.0 2.9 0.22 11.6 0.1 2.4 2 0 0 2 2 2 0 Basic region leucine zipper FliJ PF02050.16 OAP64981.1 - 0.051 13.8 3.7 0.13 12.5 3.7 1.6 1 1 0 1 1 1 0 Flagellar FliJ protein TSC22 PF01166.18 OAP64981.1 - 1.9 8.9 4.9 1.9 8.9 0.2 2.3 2 0 0 2 2 2 0 TSC-22/dip/bun family PI3Ka PF00613.20 OAP64982.1 - 7.6e-50 168.9 0.2 1.3e-49 168.2 0.2 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 OAP64982.1 - 1.8e-46 159.0 0.0 6e-32 111.4 0.0 3.3 3 1 1 4 4 4 2 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 OAP64982.1 - 8.5e-28 97.0 0.0 1.7e-27 96.1 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 Ribonucleas_3_3 PF14622.6 OAP64982.1 - 0.1 12.7 0.5 4.9 7.3 0.0 3.0 3 0 0 3 3 3 0 Ribonuclease-III-like Nse4_C PF08743.10 OAP64983.1 - 8.7e-33 112.5 0.0 2.5e-32 111.0 0.0 1.8 1 0 0 1 1 1 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.6 OAP64983.1 - 1.5e-11 44.2 0.0 3.8e-11 42.9 0.0 1.8 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE TAF8_C PF10406.9 OAP64983.1 - 0.77 10.4 2.7 3.4 8.3 2.7 2.2 1 0 0 1 1 1 0 Transcription factor TFIID complex subunit 8 C-term MFS_1 PF07690.16 OAP64984.1 - 6.1e-31 107.6 25.3 8.7e-31 107.1 25.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Pyr_redox_2 PF07992.14 OAP64985.1 - 7.5e-57 192.8 0.4 1.9e-56 191.5 0.3 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 OAP64985.1 - 1.6e-31 108.8 0.2 3.4e-31 107.8 0.2 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 OAP64985.1 - 9.6e-15 54.9 0.2 9.6e-15 54.9 0.2 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAP64985.1 - 3.3e-06 26.6 0.0 3.3e-06 26.6 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OAP64985.1 - 0.024 13.7 1.7 0.067 12.3 0.7 2.2 4 1 0 4 4 4 0 Glucose inhibited division protein A K_oxygenase PF13434.6 OAP64985.1 - 0.049 12.8 0.0 0.082 12.0 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 OAP64985.1 - 0.25 10.5 1.7 0.53 9.5 1.7 1.5 1 0 0 1 1 1 0 Thi4 family ECH_1 PF00378.20 OAP64986.1 - 6.6e-43 146.8 0.0 1.2e-42 146.0 0.0 1.3 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAP64986.1 - 2e-24 86.7 0.0 3.1e-24 86.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Ribosomal_L7Ae PF01248.26 OAP64988.1 - 3.2e-27 94.1 0.1 4e-27 93.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 OAP64988.1 - 0.0021 17.9 0.0 0.0028 17.5 0.0 1.2 1 0 0 1 1 1 1 PELOTA RNA binding domain ATP-synt_C PF00137.21 OAP64989.1 - 2.1e-34 117.6 33.3 6.9e-22 77.6 14.8 2.1 2 0 0 2 2 2 2 ATP synthase subunit C DUF2970 PF11174.8 OAP64989.1 - 4.9 7.1 10.5 1.3 8.9 1.7 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) DUF1713 PF08213.11 OAP64990.1 - 1.6e-12 47.1 18.2 3e-12 46.2 18.2 1.5 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) Dabb PF07876.12 OAP64991.1 - 2.4e-10 40.9 0.1 2.9e-10 40.7 0.1 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Ank_4 PF13637.6 OAP64992.1 - 1.4e-07 31.9 1.2 0.18 12.4 0.0 5.0 2 2 3 5 5 5 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 OAP64992.1 - 5e-07 30.2 0.0 0.0017 18.9 0.0 3.4 2 1 1 3 3 3 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OAP64992.1 - 0.00043 20.5 0.0 0.37 11.5 0.0 4.8 5 0 0 5 5 5 1 Ankyrin repeat Ank_5 PF13857.6 OAP64992.1 - 0.018 15.4 0.1 7.2 7.1 0.0 3.9 3 1 2 5 5 5 0 Ankyrin repeats (many copies) NCU-G1 PF15065.6 OAP64992.1 - 0.068 12.1 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Lysosomal transcription factor, NCU-G1 SesA PF17107.5 OAP64992.1 - 0.26 11.5 3.2 0.81 9.9 0.1 3.0 3 1 0 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Syntaxin_2 PF14523.6 OAP64992.1 - 1.2 9.5 3.2 1.3 9.4 0.5 2.4 2 1 0 2 2 2 0 Syntaxin-like protein ThiF PF00899.21 OAP64993.1 - 9e-43 146.4 0.0 1.5e-42 145.7 0.0 1.2 1 0 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 OAP64993.1 - 0.00092 19.5 1.5 0.39 11.0 0.2 2.9 3 0 0 3 3 3 2 Saccharopine dehydrogenase NADP binding domain NAD_binding_7 PF13241.6 OAP64993.1 - 0.0015 18.9 0.2 0.0036 17.7 0.2 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.14 OAP64993.1 - 0.0055 16.3 0.1 0.014 15.0 0.1 1.7 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.18 OAP64993.1 - 0.011 16.0 1.7 0.04 14.2 0.1 2.6 3 0 0 3 3 3 0 TrkA-N domain Rib_5-P_isom_A PF06026.14 OAP64993.1 - 0.079 12.6 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) Shikimate_DH PF01488.20 OAP64993.1 - 0.25 11.4 1.3 1.8 8.6 0.1 2.7 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Isy1 PF06246.12 OAP64994.1 - 2.8e-86 289.2 0.7 3.2e-86 289.0 0.7 1.0 1 0 0 1 1 1 1 Isy1-like splicing family AAA_lid_10 PF17872.1 OAP64994.1 - 0.093 12.9 0.0 0.26 11.4 0.0 1.8 1 1 0 1 1 1 0 AAA lid domain CAP59_mtransfer PF11735.8 OAP64996.1 - 1.3e-79 267.3 0.0 1.6e-79 267.0 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 MaoC_dehydratas PF01575.19 OAP64997.1 - 0.00018 21.1 0.0 0.00031 20.3 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain CENP-T_C PF15511.6 OAP64998.1 - 8.3e-37 125.6 0.7 2.4e-36 124.2 0.1 2.0 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 OAP64998.1 - 1.1e-09 38.5 0.1 2e-09 37.7 0.1 1.4 1 0 0 1 1 1 1 CENP-S protein Histone PF00125.24 OAP64998.1 - 0.00033 21.0 1.7 0.00033 21.0 1.7 2.1 2 1 0 2 2 2 1 Core histone H2A/H2B/H3/H4 SURF1 PF02104.15 OAP64999.1 - 7.5e-45 153.3 0.0 9.5e-45 153.0 0.0 1.1 1 0 0 1 1 1 1 SURF1 family UBX PF00789.20 OAP65000.1 - 8.2e-09 35.5 0.0 3.3e-08 33.6 0.0 2.1 2 0 0 2 2 2 1 UBX domain Thioredoxin_7 PF13899.6 OAP65000.1 - 0.12 12.6 0.0 0.41 10.9 0.0 1.8 2 0 0 2 2 2 0 Thioredoxin-like TFB6 PF17110.5 OAP65001.1 - 5.5e-37 127.2 0.0 6.9e-37 126.8 0.0 1.1 1 0 0 1 1 1 1 Subunit 11 of the general transcription factor TFIIH Ribosomal_60s PF00428.19 OAP65001.1 - 0.048 14.2 0.1 0.048 14.2 0.1 1.9 2 0 0 2 2 2 0 60s Acidic ribosomal protein Amidohydro_2 PF04909.14 OAP65002.1 - 7.4e-21 75.2 3.0 1.9e-20 73.8 3.0 1.7 1 1 0 1 1 1 1 Amidohydrolase adh_short_C2 PF13561.6 OAP65003.1 - 1.7e-52 178.3 0.0 3.7e-48 164.1 0.0 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP65003.1 - 5.5e-39 133.7 0.0 1.2e-33 116.2 0.0 2.0 1 1 1 2 2 2 2 short chain dehydrogenase KR PF08659.10 OAP65003.1 - 7.3e-09 35.8 0.1 4.9e-08 33.1 0.1 1.9 1 1 0 1 1 1 1 KR domain Fungal_trans PF04082.18 OAP65005.1 - 5.6e-20 71.5 0.0 8.1e-20 71.0 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP65005.1 - 4.3e-08 33.1 11.8 8.2e-08 32.2 11.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MR_MLE_C PF13378.6 OAP65006.1 - 5.7e-39 134.0 0.0 1.1e-38 133.0 0.0 1.4 2 0 0 2 2 2 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 OAP65006.1 - 1.6e-09 38.0 0.0 2.5e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Pyr_redox_3 PF13738.6 OAP65007.1 - 2.3e-16 60.0 0.3 2.7e-15 56.4 0.1 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 OAP65007.1 - 7.5e-14 51.0 0.0 1.4e-13 50.2 0.0 1.3 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 OAP65007.1 - 4.9e-11 42.4 0.0 4.3e-09 36.0 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAP65007.1 - 6.4e-10 38.7 0.0 6.7e-09 35.3 0.0 2.0 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 OAP65007.1 - 0.00045 19.6 0.0 0.0051 16.1 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 OAP65007.1 - 0.0014 18.9 0.0 0.0037 17.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 OAP65007.1 - 0.0023 16.7 0.1 0.035 12.8 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.24 OAP65007.1 - 0.005 16.5 0.9 0.88 9.1 0.5 2.3 1 1 0 2 2 2 2 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 OAP65007.1 - 0.0067 15.7 0.0 0.18 11.1 0.0 2.2 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 OAP65007.1 - 0.0095 15.1 0.5 0.049 12.7 0.3 2.0 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 OAP65007.1 - 0.034 14.7 0.1 3.9 8.1 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OAP65007.1 - 0.075 12.1 0.1 0.23 10.5 0.1 1.8 3 0 0 3 3 3 0 Lycopene cyclase protein LAM_C PF12544.8 OAP65007.1 - 0.13 12.4 0.0 0.33 11.1 0.0 1.7 1 0 0 1 1 1 0 Lysine-2,3-aminomutase Shikimate_DH PF01488.20 OAP65007.1 - 0.25 11.4 0.0 3.5 7.7 0.0 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Pyr_redox_2 PF07992.14 OAP65008.1 - 1e-49 169.4 0.6 1.3e-49 169.0 0.6 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 OAP65008.1 - 3.8e-26 91.5 0.1 1.5e-25 89.6 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 OAP65008.1 - 4.5e-19 68.8 2.0 1.1e-17 64.3 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OAP65008.1 - 3.1e-08 33.1 0.2 0.0014 17.8 0.1 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 OAP65008.1 - 1.8e-06 27.5 0.5 6.3e-05 22.4 0.0 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAP65008.1 - 5e-05 23.4 1.6 0.11 12.8 0.0 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 OAP65008.1 - 0.00011 21.7 2.2 0.012 15.0 0.7 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 OAP65008.1 - 0.00029 20.2 0.1 0.16 11.2 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain 3HCDH_N PF02737.18 OAP65008.1 - 0.00055 19.9 1.4 0.015 15.2 0.1 2.4 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain XdhC_C PF13478.6 OAP65008.1 - 0.0024 18.4 0.2 0.057 13.9 0.0 2.5 2 1 0 2 2 2 1 XdhC Rossmann domain AlaDh_PNT_C PF01262.21 OAP65008.1 - 0.0025 17.2 0.2 0.011 15.0 0.1 2.0 2 1 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 OAP65008.1 - 0.0035 16.7 0.1 0.0093 15.3 0.1 1.8 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 OAP65008.1 - 0.0085 15.7 1.4 0.05 13.2 0.0 2.3 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA Lycopene_cycl PF05834.12 OAP65008.1 - 0.023 13.7 3.1 0.71 8.9 0.0 2.8 2 1 1 3 3 3 0 Lycopene cyclase protein NAD_binding_7 PF13241.6 OAP65008.1 - 0.035 14.6 0.3 0.17 12.4 0.1 2.1 2 0 0 2 2 2 0 Putative NAD(P)-binding HI0933_like PF03486.14 OAP65008.1 - 0.094 11.4 4.9 1 8.0 0.2 3.0 2 1 1 3 3 3 0 HI0933-like protein NAD_Gly3P_dh_N PF01210.23 OAP65008.1 - 0.1 12.5 0.1 1.3 9.0 0.0 2.3 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ThiF PF00899.21 OAP65008.1 - 0.19 11.1 1.3 1.3 8.4 0.1 2.2 2 0 0 2 2 2 0 ThiF family FAD_binding_2 PF00890.24 OAP65008.1 - 0.19 10.7 7.9 0.043 12.9 1.6 2.4 3 0 0 3 3 3 0 FAD binding domain DAO PF01266.24 OAP65008.1 - 0.22 11.1 3.2 5 6.6 0.0 3.2 3 0 0 3 3 3 0 FAD dependent oxidoreductase An_peroxidase PF03098.15 OAP65009.1 - 1.5e-39 136.0 0.0 4.3e-29 101.5 0.0 3.6 1 1 1 2 2 2 2 Animal haem peroxidase p450 PF00067.22 OAP65009.1 - 9.3e-08 31.2 0.0 1.7e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 Ribosomal_L14 PF00238.19 OAP65010.1 - 2.7e-34 117.9 0.0 3.3e-34 117.6 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Fungal_trans_2 PF11951.8 OAP65011.1 - 2.5e-06 26.6 3.3 2.5e-06 26.6 3.3 2.0 2 1 0 3 3 3 1 Fungal specific transcription factor domain Peptidase_C12 PF01088.21 OAP65012.1 - 4.7e-65 219.3 0.0 6.1e-65 218.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 OAP65012.1 - 2.1e-10 40.3 0.5 4.6e-10 39.2 0.5 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases DUF2087 PF09860.9 OAP65012.1 - 0.13 12.4 0.8 2 8.6 0.2 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2087) zf-C2H2_4 PF13894.6 OAP65014.1 - 3.6e-07 30.5 1.7 0.0088 16.8 0.1 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 OAP65014.1 - 0.00048 20.4 2.7 0.014 15.8 0.1 2.4 2 0 0 2 2 2 1 Zinc finger, C2H2 type LicD PF04991.13 OAP65014.1 - 0.028 14.5 0.0 0.053 13.7 0.0 1.4 1 0 0 1 1 1 0 LicD family Ima1_N PF09779.9 OAP65014.1 - 1.2 10.0 3.5 0.76 10.6 0.7 2.1 2 1 0 2 2 2 0 Ima1 N-terminal domain DUF4629 PF15442.6 OAP65014.1 - 6.5 7.0 12.3 1.5 9.0 4.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4629) HEAT_EZ PF13513.6 OAP65015.1 - 2.7e-34 117.2 4.3 6.8e-16 58.4 0.1 10.0 10 1 1 11 11 10 5 HEAT-like repeat HEAT PF02985.22 OAP65015.1 - 3.4e-23 79.7 12.4 8.6e-05 22.5 0.0 10.0 11 0 0 11 11 10 4 HEAT repeat HEAT_2 PF13646.6 OAP65015.1 - 9e-19 67.7 0.3 7.7e-05 23.0 0.0 6.9 4 2 3 8 8 8 3 HEAT repeats Vac14_Fab1_bd PF12755.7 OAP65015.1 - 6.4e-10 39.5 0.0 0.051 14.2 0.0 6.1 4 3 3 7 7 6 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 OAP65015.1 - 1.3e-08 35.0 0.0 0.00082 19.4 0.0 4.5 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 MMS19_C PF12460.8 OAP65015.1 - 3.8e-06 26.3 5.0 0.79 8.8 0.0 5.0 4 1 1 5 5 5 2 RNAPII transcription regulator C-terminal IBN_N PF03810.19 OAP65015.1 - 7e-06 25.9 2.1 0.0093 15.9 0.1 4.9 3 1 1 4 4 4 1 Importin-beta N-terminal domain DRIM PF07539.12 OAP65015.1 - 3.7e-05 22.3 0.0 0.062 11.6 0.0 3.2 2 1 1 3 3 3 2 Down-regulated in metastasis CLASP_N PF12348.8 OAP65015.1 - 0.00013 21.6 0.0 3.3 7.2 0.0 4.5 5 1 0 5 5 5 1 CLASP N terminal Adaptin_N PF01602.20 OAP65015.1 - 0.00028 19.6 0.1 0.067 11.7 0.0 3.1 2 1 0 2 2 2 1 Adaptin N terminal region HEAT_PBS PF03130.16 OAP65015.1 - 0.0017 18.9 3.1 3.7 8.5 0.0 6.0 7 0 0 7 7 5 1 PBS lyase HEAT-like repeat RTP1_C1 PF10363.9 OAP65015.1 - 0.0037 17.4 0.2 0.21 11.8 0.0 3.3 4 0 0 4 4 3 1 Required for nuclear transport of RNA pol II C-terminus 1 TAF6_C PF07571.13 OAP65015.1 - 0.026 14.8 0.0 1.5 9.2 0.0 3.3 3 0 0 3 3 3 0 TAF6 C-terminal HEAT repeat domain Arm PF00514.23 OAP65015.1 - 0.03 14.4 3.3 1 9.5 0.0 4.6 4 1 0 4 4 4 0 Armadillo/beta-catenin-like repeat DUF3437 PF11919.8 OAP65015.1 - 0.17 11.8 0.1 1 9.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) Proteasom_PSMB PF10508.9 OAP65015.1 - 0.17 10.3 0.0 0.43 9.0 0.0 1.6 2 0 0 2 2 2 0 Proteasome non-ATPase 26S subunit RIX1 PF08167.12 OAP65015.1 - 0.19 11.5 1.1 26 4.5 0.0 4.5 6 0 0 6 6 6 0 rRNA processing/ribosome biogenesis Syja_N PF02383.18 OAP65016.1 - 2.3e-90 303.2 0.0 3.9e-90 302.4 0.0 1.4 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.8 OAP65016.1 - 1.6e-37 127.7 0.2 4.7e-37 126.2 0.1 1.9 2 0 0 2 2 2 1 Inositol phosphatase Pox_A11 PF05061.13 OAP65016.1 - 0.13 11.5 0.2 0.24 10.7 0.2 1.3 1 0 0 1 1 1 0 Poxvirus A11 Protein Pkinase PF00069.25 OAP65017.1 - 2.6e-52 177.8 0.0 8.3e-50 169.6 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAP65017.1 - 7e-29 100.9 0.0 5.2e-28 98.0 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Seadorna_VP7 PF07387.11 OAP65017.1 - 0.0039 16.3 0.1 0.007 15.5 0.1 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Kinase-like PF14531.6 OAP65017.1 - 0.0039 16.5 0.0 0.0058 16.0 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OAP65017.1 - 0.04 12.9 0.0 0.056 12.4 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Sec_GG PF07549.14 OAP65017.1 - 0.2 11.2 1.4 0.31 10.6 0.2 2.0 2 0 0 2 2 2 0 SecD/SecF GG Motif APH PF01636.23 OAP65017.1 - 0.21 11.5 0.1 1 9.3 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Mem_trans PF03547.18 OAP65018.1 - 1.2e-53 181.9 0.0 8.1e-32 110.1 0.0 2.0 2 0 0 2 2 2 2 Membrane transport protein ETF PF01012.21 OAP65018.1 - 0.19 11.6 0.0 0.35 10.7 0.0 1.3 1 0 0 1 1 1 0 Electron transfer flavoprotein domain ADH_zinc_N_2 PF13602.6 OAP65019.1 - 1.1e-15 58.8 0.0 2.5e-15 57.7 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 OAP65019.1 - 8.8e-05 22.5 0.0 0.00018 21.5 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DXP_reductoisom PF02670.16 OAP65019.1 - 0.14 12.8 0.1 0.32 11.7 0.1 1.6 2 0 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Hist_deacetyl PF00850.19 OAP65020.1 - 1.2e-80 271.3 0.1 4.4e-80 269.4 0.0 1.8 2 0 0 2 2 2 1 Histone deacetylase domain JAB PF01398.21 OAP65021.1 - 4.7e-32 110.4 0.0 7.6e-32 109.8 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 OAP65021.1 - 4.7e-12 46.3 0.3 9.4e-12 45.3 0.3 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 OAP65021.1 - 4.5e-07 29.7 0.0 8.7e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain DUF4570 PF15134.6 OAP65021.1 - 0.042 13.9 0.1 0.078 13.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4570) NIF PF03031.18 OAP65023.1 - 3.7e-38 130.7 0.0 5.6e-38 130.2 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Ndc1_Nup PF09531.10 OAP65023.1 - 5 5.7 5.1 2.3 6.8 2.8 1.6 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup F-box-like PF12937.7 OAP65024.1 - 0.0043 16.9 0.2 0.0095 15.8 0.2 1.6 1 0 0 1 1 1 1 F-box-like 2-Hacid_dh_C PF02826.19 OAP65025.1 - 3.6e-42 143.7 0.0 4.9e-42 143.3 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 OAP65025.1 - 3.4e-05 23.5 0.0 7.7e-05 22.4 0.0 1.6 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain XdhC_C PF13478.6 OAP65025.1 - 0.0044 17.5 0.1 0.015 15.8 0.0 1.8 2 0 0 2 2 2 1 XdhC Rossmann domain NAD_binding_7 PF13241.6 OAP65025.1 - 0.11 13.0 0.0 1.7 9.1 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding TrkH PF02386.16 OAP65026.1 - 4.6e-92 309.1 3.1 1.5e-87 294.2 0.3 2.0 2 0 0 2 2 2 2 Cation transport protein Trp_syntA PF00290.20 OAP65026.1 - 0.052 12.4 0.0 0.083 11.7 0.0 1.2 1 0 0 1 1 1 0 Tryptophan synthase alpha chain DUF2470 PF10615.9 OAP65027.1 - 1.3e-21 77.0 0.6 1.8e-21 76.5 0.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) DUF3000 PF11452.8 OAP65027.1 - 0.011 15.2 0.3 0.03 13.8 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3000) PH_10 PF15411.6 OAP65028.1 - 1.2e-32 112.8 0.0 2.4e-32 111.8 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.20 OAP65028.1 - 3.7e-29 102.3 0.9 6.2e-29 101.5 0.9 1.4 1 0 0 1 1 1 1 RhoGEF domain CDC24 PF06395.11 OAP65028.1 - 6.7e-27 93.6 0.0 1.2e-26 92.8 0.0 1.4 1 0 0 1 1 1 1 CDC24 Calponin PB1 PF00564.24 OAP65028.1 - 4.1e-08 33.0 0.0 1.5e-07 31.3 0.0 2.0 1 0 0 1 1 1 1 PB1 domain PH PF00169.29 OAP65028.1 - 0.016 15.7 0.0 0.034 14.7 0.0 1.5 1 0 0 1 1 1 0 PH domain CH PF00307.31 OAP65028.1 - 0.03 14.5 0.0 0.14 12.3 0.0 2.2 2 0 0 2 2 2 0 Calponin homology (CH) domain Abhydrolase_3 PF07859.13 OAP65029.1 - 5.1e-49 167.0 0.0 7e-49 166.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 OAP65029.1 - 2e-06 27.0 0.1 5.8e-06 25.4 0.1 1.6 1 1 0 1 1 1 1 Carboxylesterase family Mac-1 PF09028.10 OAP65029.1 - 0.045 12.8 0.0 0.065 12.3 0.0 1.1 1 0 0 1 1 1 0 Mac 1 Utp11 PF03998.13 OAP65030.1 - 7.8e-56 189.7 16.2 9.7e-56 189.4 16.2 1.1 1 0 0 1 1 1 1 Utp11 protein SLATT_5 PF18160.1 OAP65030.1 - 0.14 11.5 0.1 0.24 10.7 0.1 1.3 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 Cmc1 PF08583.10 OAP65031.1 - 1.4e-18 66.7 1.1 1.4e-18 66.7 1.1 2.2 2 1 0 2 2 2 1 Cytochrome c oxidase biogenesis protein Cmc1 like COX17 PF05051.13 OAP65031.1 - 0.063 13.6 0.5 1.6 9.2 0.0 2.3 2 0 0 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) eIF3_N PF09440.10 OAP65031.1 - 1.5 9.3 4.3 2.3 8.7 4.3 1.3 1 0 0 1 1 1 0 eIF3 subunit 6 N terminal domain CAF1 PF04857.20 OAP65031.1 - 2.5 7.2 6.2 3.6 6.7 6.2 1.2 1 0 0 1 1 1 0 CAF1 family ribonuclease DBINO PF13892.6 OAP65031.1 - 6.1 7.2 19.6 11 6.4 19.5 1.5 1 1 0 1 1 1 0 DNA-binding domain DUF1682 PF07946.14 OAP65031.1 - 7.8 5.6 14.8 10 5.2 14.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Metal_resist PF13801.6 OAP65031.1 - 8.1 6.7 15.6 0.92 9.7 0.4 2.3 2 1 0 2 2 2 0 Heavy-metal resistance Aminotran_3 PF00202.21 OAP65033.1 - 1.1e-47 162.6 0.0 2.1e-46 158.4 0.0 2.5 2 1 0 2 2 2 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 OAP65033.1 - 0.041 13.0 0.0 0.073 12.2 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II Beta_elim_lyase PF01212.21 OAP65033.1 - 0.07 12.4 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Aminotran_1_2 PF00155.21 OAP65034.1 - 7.3e-37 127.4 0.0 8.4e-37 127.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Mfa1 PF17445.2 OAP65035.1 - 0.15 12.1 7.3 3.5 7.7 0.6 2.8 2 0 0 2 2 2 0 Mating factor A1 DUF4778 PF16008.5 OAP65035.1 - 0.19 11.8 5.7 0.23 11.5 5.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) Presenilin PF01080.17 OAP65035.1 - 0.71 8.6 7.1 0.7 8.6 7.1 1.1 1 0 0 1 1 1 0 Presenilin LAP1C PF05609.12 OAP65035.1 - 5.8 5.9 9.7 6.6 5.7 9.7 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) HET PF06985.11 OAP65038.1 - 2.6e-05 24.6 0.1 7.4e-05 23.1 0.0 1.9 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) MnmE_helical PF12631.7 OAP65039.1 - 7.3e-32 111.2 0.6 9.2e-27 94.6 0.7 2.1 2 0 0 2 2 2 2 MnmE helical domain TrmE_N PF10396.9 OAP65039.1 - 4.4e-22 78.6 0.0 1.9e-21 76.5 0.0 2.2 3 0 0 3 3 2 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.23 OAP65039.1 - 1.1e-18 67.3 0.0 1.9e-18 66.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 OAP65039.1 - 9.1e-06 25.8 0.0 2.4e-05 24.5 0.0 1.6 1 1 0 1 1 1 1 Dynamin family FeoB_N PF02421.18 OAP65039.1 - 4.8e-05 22.9 0.0 0.00016 21.3 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 OAP65039.1 - 0.00012 21.7 0.1 0.021 14.3 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OAP65039.1 - 0.00089 19.2 0.1 0.28 11.1 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_24 PF13479.6 OAP65039.1 - 0.022 14.5 0.0 0.043 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Glyco_hydro_3_C PF01915.22 OAP65039.1 - 0.034 14.1 0.0 0.073 13.0 0.0 1.6 1 1 1 2 2 2 0 Glycosyl hydrolase family 3 C-terminal domain ABC_tran PF00005.27 OAP65039.1 - 0.066 13.7 0.0 0.18 12.3 0.0 1.8 2 0 0 2 2 2 0 ABC transporter G-alpha PF00503.20 OAP65039.1 - 0.073 12.2 0.1 0.33 10.1 0.0 2.0 2 0 0 2 2 2 0 G-protein alpha subunit Roc PF08477.13 OAP65039.1 - 0.11 12.7 0.0 1.8 8.8 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase CAP PF00188.26 OAP65040.1 - 1.7e-16 61.2 0.2 2.4e-16 60.7 0.2 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family MFS_1 PF07690.16 OAP65041.1 - 8.1e-51 173.0 26.6 2.7e-45 154.9 13.1 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAP65041.1 - 7.3e-10 38.3 11.0 7.3e-10 38.3 11.0 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 OAP65041.1 - 0.8 7.9 7.4 0.14 10.4 1.4 2.5 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family LNP1 PF15419.6 OAP65041.1 - 2.2 8.5 6.6 0.71 10.1 2.7 2.0 2 0 0 2 2 2 0 Leukemia NUP98 fusion partner 1 Stn1 PF10451.9 OAP65042.1 - 7e-11 41.6 0.7 1.1e-09 37.7 0.0 2.3 2 1 0 2 2 2 1 Telomere regulation protein Stn1 tRNA_anti-codon PF01336.25 OAP65042.1 - 0.003 17.5 0.0 0.019 14.9 0.0 2.0 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain MIF4G PF02854.19 OAP65043.1 - 3e-51 174.1 0.0 4.8e-51 173.4 0.0 1.3 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.8 OAP65043.1 - 1e-23 83.3 0.7 2.9e-23 81.8 0.7 1.9 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 Borrelia_P83 PF05262.11 OAP65043.1 - 0.077 11.5 35.2 0.12 10.8 35.2 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Hamartin PF04388.12 OAP65043.1 - 1.9 7.0 29.4 4.4 5.8 29.4 1.7 1 0 0 1 1 1 0 Hamartin protein DnaJ PF00226.31 OAP65044.1 - 2.4e-23 82.0 2.8 8e-23 80.4 2.8 2.0 1 0 0 1 1 1 1 DnaJ domain Granulin PF00396.18 OAP65046.1 - 7.2 7.0 14.3 91 3.5 14.3 2.2 1 1 0 1 1 1 0 Granulin Usp PF00582.26 OAP65047.1 - 6.7e-16 59.1 8.8 1.2e-15 58.3 1.2 3.5 2 1 0 2 2 2 1 Universal stress protein family Zip PF02535.22 OAP65047.1 - 1.8 7.7 7.8 0.041 13.1 0.7 1.8 2 0 0 2 2 2 0 ZIP Zinc transporter V_ATPase_I PF01496.19 OAP65047.1 - 6.1 4.6 4.9 9.8 3.9 4.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Inv-AAD PF18785.1 OAP65048.1 - 1.8e-34 118.4 0.1 2.5e-33 114.7 0.1 2.1 1 1 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase dCMP_cyt_deam_1 PF00383.23 OAP65048.1 - 3.2e-13 49.4 0.0 1.4e-10 41.0 0.0 2.3 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.11 OAP65048.1 - 0.0024 17.8 0.0 0.0042 17.0 0.0 1.3 1 0 0 1 1 1 1 APOBEC-like N-terminal domain CDK2AP PF09806.9 OAP65048.1 - 0.19 11.7 2.5 0.41 10.7 0.8 2.1 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein WD40 PF00400.32 OAP65049.1 - 1.5e-14 54.1 12.4 0.026 15.4 0.0 8.1 9 0 0 9 9 9 6 WD domain, G-beta repeat DUF1840 PF08895.11 OAP65049.1 - 0.029 14.7 0.8 0.067 13.5 0.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) K-box PF01486.17 OAP65049.1 - 0.13 12.4 1.0 0.35 11.1 1.0 1.6 1 0 0 1 1 1 0 K-box region bZIP_1 PF00170.21 OAP65051.1 - 4.9e-08 33.0 6.7 4.9e-08 33.0 6.7 2.1 1 1 1 2 2 2 1 bZIP transcription factor ASD2 PF08687.11 OAP65051.1 - 0.00044 19.9 1.5 0.00052 19.7 1.5 1.1 1 0 0 1 1 1 1 Apx/Shroom domain ASD2 CENP-F_leu_zip PF10473.9 OAP65051.1 - 0.0005 20.1 2.1 0.00073 19.6 2.1 1.2 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CEP63 PF17045.5 OAP65051.1 - 0.00088 19.3 3.3 0.0012 18.8 3.3 1.2 1 0 0 1 1 1 1 Centrosomal protein of 63 kDa TolA_bind_tri PF16331.5 OAP65051.1 - 0.0031 17.5 3.8 0.0067 16.5 3.8 1.5 1 0 0 1 1 1 1 TolA binding protein trimerisation DUF4618 PF15397.6 OAP65051.1 - 0.0039 16.7 1.0 0.0054 16.2 1.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4618) TMF_TATA_bd PF12325.8 OAP65051.1 - 0.0051 17.0 2.1 0.0083 16.3 2.1 1.3 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding bZIP_2 PF07716.15 OAP65051.1 - 0.0071 16.4 7.3 0.0071 16.4 7.3 2.7 2 1 1 3 3 3 1 Basic region leucine zipper SHE3 PF17078.5 OAP65051.1 - 0.01 15.5 2.7 0.016 14.9 2.7 1.3 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 DUF4094 PF13334.6 OAP65051.1 - 0.011 16.1 1.0 0.02 15.3 1.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) CLZ PF16526.5 OAP65051.1 - 0.015 15.7 3.5 0.026 14.9 3.5 1.4 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels APG6_N PF17675.1 OAP65051.1 - 0.059 13.9 4.4 0.087 13.3 4.4 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region FlxA PF14282.6 OAP65051.1 - 0.065 13.2 1.5 0.18 11.8 1.5 1.7 1 1 0 1 1 1 0 FlxA-like protein PI3K_P85_iSH2 PF16454.5 OAP65051.1 - 0.11 12.1 4.8 0.15 11.6 4.8 1.2 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain ABC_tran_CTD PF16326.5 OAP65051.1 - 0.14 12.4 1.7 0.26 11.6 1.7 1.4 1 0 0 1 1 1 0 ABC transporter C-terminal domain Jnk-SapK_ap_N PF09744.9 OAP65051.1 - 0.29 11.4 6.3 0.39 10.9 6.3 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 bZIP_Maf PF03131.17 OAP65051.1 - 1.2 9.7 14.3 0.083 13.4 8.7 1.8 1 1 1 2 2 2 0 bZIP Maf transcription factor DivIC PF04977.15 OAP65051.1 - 1.5 8.6 3.9 1.5 8.7 0.7 2.1 1 1 1 2 2 2 0 Septum formation initiator GvpL_GvpF PF06386.11 OAP65051.1 - 2.3 8.1 6.4 3.2 7.6 6.0 1.3 1 1 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF G-alpha PF00503.20 OAP65052.1 - 3.6e-110 368.5 2.7 4.3e-110 368.2 2.7 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 OAP65052.1 - 1.9e-13 50.2 1.3 1.9e-08 34.0 0.0 3.1 3 1 0 3 3 3 2 ADP-ribosylation factor family Roc PF08477.13 OAP65052.1 - 0.0013 18.9 3.9 0.81 9.9 0.0 3.7 3 1 1 4 4 4 1 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 OAP65052.1 - 0.0055 16.1 0.0 0.0096 15.3 0.0 1.5 1 0 0 1 1 1 1 Bacterial TniB protein Gtr1_RagA PF04670.12 OAP65052.1 - 0.012 15.0 4.0 0.76 9.1 0.2 2.7 2 2 0 2 2 2 0 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OAP65052.1 - 0.033 14.3 0.0 14 5.8 0.0 3.0 3 0 0 3 3 3 0 50S ribosome-binding GTPase AAA_16 PF13191.6 OAP65052.1 - 0.072 13.5 0.0 0.14 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 OAP65052.1 - 0.083 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 OAP65052.1 - 0.24 10.7 1.8 1 8.7 0.1 2.3 2 1 1 3 3 3 0 FtsK/SpoIIIE family GSHPx PF00255.19 OAP65054.1 - 8.6e-36 121.8 0.1 1.1e-35 121.5 0.1 1.1 1 0 0 1 1 1 1 Glutathione peroxidase TMEM154 PF15102.6 OAP65055.1 - 0.00035 20.5 0.0 0.00042 20.2 0.0 1.3 1 0 0 1 1 1 1 TMEM154 protein family Orf78 PF06024.12 OAP65055.1 - 0.0017 18.6 0.1 0.0044 17.3 0.0 1.7 2 0 0 2 2 2 1 Orf78 (ac78) EphA2_TM PF14575.6 OAP65055.1 - 0.0019 19.1 0.0 0.0029 18.5 0.0 1.3 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain CcmD PF04995.14 OAP65055.1 - 0.012 15.7 1.9 0.012 15.7 1.9 1.7 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) SIT PF15330.6 OAP65055.1 - 0.014 15.9 0.0 0.025 15.0 0.0 1.5 2 0 0 2 2 1 0 SHP2-interacting transmembrane adaptor protein, SIT BatD PF13584.6 OAP65055.1 - 0.018 13.9 0.0 0.018 13.9 0.0 1.1 1 0 0 1 1 1 0 Oxygen tolerance DUF2269 PF10027.9 OAP65055.1 - 0.019 15.0 0.0 0.024 14.7 0.0 1.1 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2269) DUF4381 PF14316.6 OAP65055.1 - 0.02 15.1 0.0 0.026 14.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) 7TM_GPCR_Srv PF10323.9 OAP65055.1 - 0.023 14.1 0.0 0.03 13.7 0.0 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv MscL PF01741.18 OAP65055.1 - 0.024 15.0 0.0 0.029 14.7 0.0 1.2 1 0 0 1 1 1 0 Large-conductance mechanosensitive channel, MscL DUF2615 PF11027.8 OAP65055.1 - 0.024 14.8 0.1 0.043 13.9 0.0 1.5 2 0 0 2 2 1 0 Protein of unknown function (DUF2615) DUF5385 PF17359.2 OAP65055.1 - 0.034 13.7 0.0 0.042 13.4 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5385) Stevor PF17410.2 OAP65055.1 - 0.065 12.8 0.0 0.091 12.3 0.0 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame MAP17 PF15807.5 OAP65055.1 - 0.08 13.2 0.0 0.11 12.7 0.0 1.1 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 YajC PF02699.15 OAP65055.1 - 0.087 12.7 0.1 0.13 12.2 0.1 1.2 1 0 0 1 1 1 0 Preprotein translocase subunit LapA_dom PF06305.11 OAP65055.1 - 0.09 12.6 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Vpu PF00558.19 OAP65055.1 - 0.092 12.5 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Vpu protein CCB1 PF12046.8 OAP65055.1 - 0.098 12.0 0.0 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 Cofactor assembly of complex C subunit B Cadherin_C_2 PF16492.5 OAP65055.1 - 0.12 13.2 0.0 0.19 12.5 0.0 1.4 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal Chordopox_A13L PF05961.11 OAP65055.1 - 0.14 12.4 0.0 0.38 11.0 0.0 1.7 1 0 0 1 1 1 0 Chordopoxvirus A13L protein DUF3377 PF11857.8 OAP65055.1 - 0.49 10.4 3.2 0.56 10.2 2.4 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3377) Melittin PF01372.17 OAP65055.1 - 0.63 10.1 2.0 1.8 8.7 0.1 2.2 2 0 0 2 2 2 0 Melittin LNS2 PF08235.13 OAP65056.1 - 5.5e-95 317.1 0.0 7.6e-95 316.7 0.0 1.2 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 OAP65056.1 - 6.2e-41 138.5 0.0 1.2e-40 137.6 0.0 1.5 1 0 0 1 1 1 1 lipin, N-terminal conserved region Acid_phosphat_B PF03767.14 OAP65056.1 - 0.012 15.2 0.0 0.33 10.5 0.0 2.6 3 0 0 3 3 3 0 HAD superfamily, subfamily IIIB (Acid phosphatase) FAM176 PF14851.6 OAP65056.1 - 4.9 6.8 9.4 12 5.5 9.4 1.6 1 0 0 1 1 1 0 FAM176 family TFIID-31kDa PF02291.15 OAP65057.1 - 7.1e-42 142.3 0.0 9.5e-42 141.9 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Fungal_trans PF04082.18 OAP65058.1 - 1.1e-15 57.4 0.2 1.8e-15 56.7 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP65058.1 - 2.1e-09 37.3 8.5 4.7e-09 36.2 8.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TauD PF02668.16 OAP65059.1 - 7.2e-37 127.6 0.1 9.5e-37 127.2 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.16 OAP65060.1 - 2.2e-26 92.7 25.6 2.2e-26 92.7 25.6 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily fn3 PF00041.21 OAP65060.1 - 1.6e-05 25.1 0.2 5.3e-05 23.5 0.2 1.9 1 1 0 1 1 1 1 Fibronectin type III domain DUF5337 PF17272.2 OAP65060.1 - 0.0072 16.1 4.6 0.021 14.6 4.6 1.7 1 0 0 1 1 1 1 Family of unknown function (DUF5337) Pur_ac_phosph_N PF16656.5 OAP65060.1 - 0.52 10.9 2.8 0.78 10.4 0.1 2.7 2 1 0 2 2 2 0 Purple acid Phosphatase, N-terminal domain YndJ PF14158.6 OAP65060.1 - 1.6 8.0 6.6 0.33 10.2 1.3 2.1 2 0 0 2 2 2 0 YndJ-like protein COG2 PF06148.11 OAP65060.1 - 9.1 6.4 23.1 0.085 12.9 3.8 3.2 3 1 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Thg1 PF04446.12 OAP65061.1 - 1.9e-47 160.4 0.0 3.3e-47 159.6 0.0 1.4 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.6 OAP65061.1 - 1e-44 151.6 5.0 1.4e-40 138.2 0.6 2.5 2 1 0 2 2 2 2 Thg1 C terminal domain GCIP PF13324.6 OAP65061.1 - 0.0077 15.9 0.5 0.012 15.2 0.5 1.2 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting CENP-I PF07778.11 OAP65061.1 - 0.056 12.2 0.8 0.08 11.6 0.8 1.1 1 0 0 1 1 1 0 Mis6 MRP-S25 PF13741.6 OAP65061.1 - 0.15 11.6 0.6 0.25 10.9 0.6 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein S25 DUF3245 PF11595.8 OAP65061.1 - 0.72 10.3 8.3 1.4 9.4 8.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) PGA2 PF07543.12 OAP65061.1 - 1.1 9.2 8.6 2.1 8.3 8.6 1.4 1 0 0 1 1 1 0 Protein trafficking PGA2 FAM176 PF14851.6 OAP65061.1 - 1.2 8.8 4.1 2.5 7.7 4.1 1.5 1 0 0 1 1 1 0 FAM176 family CENP-B_dimeris PF09026.10 OAP65061.1 - 1.3 9.5 6.4 0.53 10.7 3.3 1.8 2 0 0 2 2 2 0 Centromere protein B dimerisation domain PBP1_TM PF14812.6 OAP65061.1 - 7.7 7.0 13.4 0.32 11.4 7.2 1.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Aldedh PF00171.22 OAP65062.1 - 8.9e-118 393.7 0.2 1.1e-117 393.4 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Fungal_trans PF04082.18 OAP65063.1 - 4.9e-16 58.5 0.0 1.6e-15 56.9 0.0 1.6 1 1 1 2 2 2 1 Fungal specific transcription factor domain DUF3425 PF11905.8 OAP65064.1 - 4.2e-23 81.6 0.9 7.3e-23 80.9 0.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 OAP65064.1 - 0.00026 21.0 3.6 0.00055 20.0 3.6 1.6 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 OAP65064.1 - 0.0063 16.6 3.6 0.013 15.5 3.6 1.5 1 0 0 1 1 1 1 Basic region leucine zipper Pil1 PF13805.6 OAP65064.1 - 0.01 15.3 1.4 0.016 14.7 1.4 1.2 1 0 0 1 1 1 0 Eisosome component PIL1 adh_short_C2 PF13561.6 OAP65065.1 - 9.4e-54 182.4 0.7 1.6e-53 181.7 0.7 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP65065.1 - 1.1e-45 155.6 0.4 1.6e-45 155.0 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAP65065.1 - 4.2e-12 46.3 0.2 8.3e-12 45.4 0.2 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 OAP65065.1 - 1.3e-06 28.0 0.1 2.1e-06 27.4 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OAP65065.1 - 0.00015 20.8 0.2 0.00024 20.2 0.2 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 OAP65065.1 - 0.01 15.0 0.0 0.02 14.0 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein FMO-like PF00743.19 OAP65066.1 - 2e-18 66.1 0.3 9.5e-17 60.6 0.4 2.3 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OAP65066.1 - 1.3e-12 47.8 0.0 4.8e-12 45.9 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 OAP65066.1 - 7.8e-10 38.5 0.0 1.6e-08 34.1 0.1 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAP65066.1 - 3.5e-07 29.7 0.0 8.9e-06 25.1 0.0 2.6 4 0 0 4 4 4 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 OAP65066.1 - 0.00091 18.5 0.0 0.0089 15.3 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAP65066.1 - 0.0056 15.9 0.0 0.25 10.5 0.0 2.3 2 0 0 2 2 2 1 Thi4 family ADH_N PF08240.12 OAP65067.1 - 4.7e-28 97.3 0.7 8e-28 96.5 0.7 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAP65067.1 - 7.4e-22 77.7 0.0 1.2e-21 77.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 OAP65067.1 - 2e-08 34.0 0.0 3.4e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 OAP65067.1 - 5.6e-05 24.2 0.0 0.00011 23.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_7 PF13241.6 OAP65067.1 - 0.0047 17.3 0.0 0.0087 16.5 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding FAD_binding_3 PF01494.19 OAP65067.1 - 0.0067 15.7 0.0 0.01 15.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain ADH_N_assoc PF13823.6 OAP65067.1 - 0.0076 16.2 0.1 0.018 15.0 0.1 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated 2-Hacid_dh_C PF02826.19 OAP65067.1 - 0.027 13.9 0.0 0.042 13.2 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 OAP65067.1 - 0.031 14.3 0.0 0.055 13.5 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase CIAPIN1 PF05093.13 OAP65067.1 - 0.033 14.7 0.6 0.073 13.6 0.6 1.5 1 0 0 1 1 1 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Sacchrp_dh_NADP PF03435.18 OAP65067.1 - 0.11 12.7 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain RR_TM4-6 PF06459.12 OAP65068.1 - 0.43 10.3 19.6 0.59 9.9 19.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 tRNA-synt_1d PF00750.19 OAP65070.1 - 1.8e-68 231.1 0.0 2.5e-68 230.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 OAP65070.1 - 1.8e-06 28.1 0.2 4.3e-06 26.9 0.0 1.7 2 0 0 2 2 2 1 DALR anticodon binding domain HeLo PF14479.6 OAP65070.1 - 0.044 13.6 0.1 0.085 12.7 0.1 1.4 1 0 0 1 1 1 0 Prion-inhibition and propagation Methyltransf_23 PF13489.6 OAP65072.1 - 0.0012 18.7 0.0 0.0046 16.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.6 OAP65072.1 - 0.0036 17.3 0.1 0.035 14.1 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAP65072.1 - 0.0078 16.9 0.0 0.035 14.8 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Pollen_allerg_2 PF01620.16 OAP65072.1 - 0.028 14.6 0.4 0.065 13.4 0.4 1.6 1 0 0 1 1 1 0 Ribonuclease (pollen allergen) TehB PF03848.14 OAP65072.1 - 0.13 11.7 0.0 0.28 10.6 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB STAC2_u1 PF16664.5 OAP65072.1 - 1.7 9.1 8.1 0.94 9.9 1.3 2.4 2 0 0 2 2 2 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 Mito_carr PF00153.27 OAP65074.1 - 9.1e-45 150.5 8.0 2.2e-16 59.5 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF641 PF04859.12 OAP65076.1 - 0.11 12.9 1.1 1.1 9.6 0.7 2.5 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) APG6_N PF17675.1 OAP65076.1 - 8.6 6.9 9.8 18 5.8 4.0 2.5 2 0 0 2 2 2 0 Apg6 coiled-coil region RRM_1 PF00076.22 OAP65077.1 - 3.7e-16 58.7 0.0 6e-16 58.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OAP65077.1 - 0.0021 17.7 0.0 0.0032 17.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 OAP65077.1 - 0.0049 16.9 0.0 0.0093 16.0 0.0 1.5 1 0 0 1 1 1 1 RNA binding motif PRP38_assoc PF12871.7 OAP65077.1 - 0.39 11.3 25.8 0.15 12.7 23.0 1.6 2 0 0 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Corona_nucleoca PF00937.18 OAP65077.1 - 2 7.4 11.6 3 6.8 11.6 1.3 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Phage_holin_3_6 PF07332.11 OAP65079.1 - 0.0058 16.7 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 Putative Actinobacterial Holin-X, holin superfamily III Motile_Sperm PF00635.26 OAP65080.1 - 1.2e-27 95.9 0.6 2.5e-27 94.8 0.6 1.7 1 0 0 1 1 1 1 MSP (Major sperm protein) domain Ndc1_Nup PF09531.10 OAP65080.1 - 0.0017 17.1 6.6 0.0022 16.8 6.6 1.1 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Herpes_UL49_2 PF04823.12 OAP65080.1 - 0.011 15.8 1.7 0.024 14.7 1.7 1.5 1 0 0 1 1 1 0 Herpesvirus UL49 tegument protein T3SS_needle_E PF08988.10 OAP65080.1 - 0.015 15.4 1.9 0.032 14.4 1.9 1.5 1 0 0 1 1 1 0 Type III secretion system, cytoplasmic E component of needle DUF5001 PF16392.5 OAP65080.1 - 0.023 14.6 0.1 0.06 13.3 0.1 1.7 1 0 0 1 1 1 0 Ig-like domain GLE1 PF07817.13 OAP65080.1 - 0.027 13.7 0.2 0.049 12.8 0.2 1.4 1 0 0 1 1 1 0 GLE1-like protein FixG_C PF11614.8 OAP65080.1 - 0.028 14.6 0.1 0.063 13.5 0.1 1.6 1 0 0 1 1 1 0 IG-like fold at C-terminal of FixG, putative oxidoreductase GAS PF13851.6 OAP65080.1 - 0.05 12.9 1.0 0.094 12.1 1.0 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding PapD-like PF14874.6 OAP65080.1 - 0.056 13.6 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Flagellar-associated PapD-like DotU PF09850.9 OAP65080.1 - 0.057 13.1 0.3 0.52 10.0 0.1 2.1 2 0 0 2 2 2 0 Type VI secretion system protein DotU Sas10_Utp3 PF04000.15 OAP65080.1 - 0.083 13.5 0.1 0.24 12.1 0.1 1.8 1 0 0 1 1 1 0 Sas10/Utp3/C1D family SOGA PF11365.8 OAP65080.1 - 0.1 13.7 0.2 0.33 12.1 0.3 2.0 1 1 0 1 1 1 0 Protein SOGA ABC_tran_CTD PF16326.5 OAP65080.1 - 0.23 11.7 2.9 0.47 10.8 2.9 1.5 1 0 0 1 1 1 0 ABC transporter C-terminal domain PspA_IM30 PF04012.12 OAP65080.1 - 0.35 10.4 10.6 0.57 9.7 10.6 1.2 1 0 0 1 1 1 0 PspA/IM30 family Spectrin PF00435.21 OAP65080.1 - 0.43 11.1 4.2 0.21 12.1 1.4 1.8 2 0 0 2 2 2 0 Spectrin repeat FlxA PF14282.6 OAP65080.1 - 0.66 10.0 10.3 1.5 8.9 10.3 1.6 1 1 0 1 1 1 0 FlxA-like protein UBX PF00789.20 OAP65081.1 - 6.4e-06 26.3 0.3 1.6e-05 25.0 0.1 1.9 2 0 0 2 2 2 1 UBX domain UBA PF00627.31 OAP65081.1 - 9.7e-06 25.4 0.0 2.4e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain Crystallin PF00525.18 OAP65081.1 - 0.07 13.3 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 Alpha crystallin A chain, N terminal RR_TM4-6 PF06459.12 OAP65081.1 - 0.13 12.1 27.6 0.19 11.5 27.6 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 zf-C2H2_2 PF12756.7 OAP65081.1 - 0.26 11.7 0.1 0.26 11.7 0.1 1.9 1 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2HE PF16278.5 OAP65081.1 - 0.28 11.7 0.1 0.28 11.7 0.1 3.2 2 1 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger Utp11 PF03998.13 OAP65081.1 - 0.64 9.9 26.4 0.93 9.4 26.4 1.2 1 0 0 1 1 1 0 Utp11 protein SOBP PF15279.6 OAP65081.1 - 3.6 8.1 8.1 4.6 7.8 8.1 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Hamartin PF04388.12 OAP65081.1 - 4.2 5.9 14.1 4.8 5.7 14.1 1.1 1 0 0 1 1 1 0 Hamartin protein FA_desaturase PF00487.24 OAP65084.1 - 5.8e-26 91.9 11.6 1e-25 91.0 11.6 1.4 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.10 OAP65084.1 - 1e-14 53.7 0.1 2e-14 52.8 0.1 1.5 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) EMC3_TMCO1 PF01956.16 OAP65084.1 - 0.57 9.9 3.3 1.2 8.9 3.3 1.4 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like MutS_V PF00488.21 OAP65085.1 - 1.3e-39 136.2 0.0 2.3e-39 135.4 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 OAP65085.1 - 2.8e-19 70.1 0.1 6.4e-19 68.9 0.0 1.7 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.18 OAP65085.1 - 0.0061 16.9 0.0 0.014 15.7 0.0 1.7 1 0 0 1 1 1 1 MutS family domain IV Herpes_UL14 PF03580.14 OAP65085.1 - 0.077 13.2 0.9 0.18 12.0 0.3 1.9 2 0 0 2 2 2 0 Herpesvirus UL14-like protein adh_short PF00106.25 OAP65086.1 - 2.5e-18 66.3 0.0 2.5e-16 59.7 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP65086.1 - 1.2e-10 41.4 0.0 4.5e-09 36.2 0.0 2.1 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP65086.1 - 0.00013 21.9 0.0 0.0018 18.2 0.0 2.1 2 0 0 2 2 2 1 KR domain DFP PF04127.15 OAP65086.1 - 0.014 15.3 0.1 0.023 14.5 0.1 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Glyco_transf_4 PF13439.6 OAP65086.1 - 0.039 14.0 0.0 0.062 13.3 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase Family 4 LytR_C PF13399.6 OAP65086.1 - 0.046 14.7 0.3 0.32 12.0 0.1 2.3 2 0 0 2 2 2 0 LytR cell envelope-related transcriptional attenuator THF_DHG_CYH_C PF02882.19 OAP65086.1 - 0.062 12.6 0.1 0.099 11.9 0.1 1.2 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain YjeF_N PF03853.15 OAP65086.1 - 0.098 12.5 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 YjeF-related protein N-terminus Sas10 PF09368.10 OAP65087.1 - 2.1e-30 105.0 7.2 2.1e-30 105.0 7.2 2.5 2 0 0 2 2 2 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 OAP65087.1 - 1.3e-11 45.0 0.1 6e-11 42.8 0.0 2.3 2 0 0 2 2 2 1 Sas10/Utp3/C1D family TauD PF02668.16 OAP65088.1 - 2.3e-44 152.2 0.3 3.4e-44 151.6 0.3 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.16 OAP65089.1 - 6.5e-10 38.5 19.1 9.2e-07 28.1 6.6 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 OAP65090.1 - 1.8e-36 125.8 30.0 1.8e-36 125.8 30.0 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAP65090.1 - 1.5e-08 34.0 9.4 1.5e-08 34.0 9.4 3.1 3 0 0 3 3 3 2 Sugar (and other) transporter FAD_binding_3 PF01494.19 OAP65091.1 - 6e-20 71.8 0.0 8.1e-20 71.4 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAP65091.1 - 8.6e-05 22.3 1.4 0.0021 17.7 1.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 OAP65091.1 - 9.7e-05 22.4 1.4 0.024 14.6 0.1 2.7 3 0 0 3 3 3 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 OAP65091.1 - 0.00044 20.4 0.8 0.001 19.3 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAP65091.1 - 0.0019 17.5 3.3 0.52 9.5 0.4 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 OAP65091.1 - 0.0034 16.5 0.0 0.024 13.7 0.0 2.0 1 1 0 1 1 1 1 Squalene epoxidase Trp_halogenase PF04820.14 OAP65091.1 - 0.007 15.3 0.9 0.61 8.9 0.5 2.2 2 0 0 2 2 2 2 Tryptophan halogenase Amino_oxidase PF01593.24 OAP65091.1 - 0.04 13.2 0.1 0.069 12.4 0.1 1.4 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase PAF-AH_p_II PF03403.13 OAP65092.1 - 2.3e-40 138.3 0.0 1.7e-39 135.4 0.0 1.9 1 1 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 OAP65092.1 - 9.2e-06 24.8 0.0 5.9e-05 22.1 0.0 2.0 1 1 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 OAP65092.1 - 2.5e-05 23.7 0.3 0.0098 15.2 0.1 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OAP65092.1 - 0.0014 19.3 0.2 0.0034 18.0 0.1 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Chlorophyllase PF07224.11 OAP65092.1 - 0.036 13.1 0.0 0.14 11.1 0.0 1.9 2 0 0 2 2 2 0 Chlorophyllase p450 PF00067.22 OAP65093.1 - 2e-73 247.7 0.0 2.6e-73 247.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Abhydrolase_1 PF00561.20 OAP65094.1 - 1.6e-23 83.7 0.1 2.1e-23 83.3 0.1 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAP65094.1 - 1.9e-14 54.8 0.1 2.3e-14 54.5 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAP65094.1 - 9.6e-08 31.6 0.0 1.3e-07 31.2 0.0 1.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 EHN PF06441.12 OAP65094.1 - 0.0065 16.8 0.1 0.013 15.8 0.1 1.5 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Ndr PF03096.14 OAP65094.1 - 0.16 10.6 0.0 0.25 10.0 0.0 1.2 1 0 0 1 1 1 0 Ndr family Zn_clus PF00172.18 OAP65095.1 - 0.0082 16.2 2.8 0.015 15.4 2.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RIC3 PF15361.6 OAP65095.1 - 0.033 14.6 0.1 0.41 11.0 0.0 2.2 2 0 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 Fungal_trans PF04082.18 OAP65096.1 - 3e-20 72.4 0.4 8.6e-20 70.9 0.4 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 OAP65097.1 - 3e-38 131.7 28.7 3e-38 131.7 28.7 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Cellulase PF00150.18 OAP65098.1 - 6.7e-06 25.7 1.8 0.0077 15.7 0.9 2.3 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Sugar_tr PF00083.24 OAP65099.1 - 9.9e-94 314.7 24.6 1.1e-93 314.5 24.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP65099.1 - 3.3e-29 101.9 27.1 3.3e-29 101.9 27.1 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF5345 PF17280.2 OAP65099.1 - 0.16 12.0 2.5 2.5 8.1 0.7 3.2 2 1 1 3 3 3 0 Family of unknown function (DUF5345) ubiquitin PF00240.23 OAP65101.1 - 0.032 14.0 0.0 0.074 12.8 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin family DIOX_N PF14226.6 OAP65102.1 - 2e-20 73.7 0.0 3.9e-20 72.8 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OAP65102.1 - 3.7e-13 49.8 0.1 6.1e-13 49.1 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily p450 PF00067.22 OAP65103.1 - 1.4e-52 179.0 0.0 2.1e-52 178.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PhyH PF05721.13 OAP65104.1 - 2.2e-22 80.4 0.0 3.1e-22 79.9 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) PhyH PF05721.13 OAP65105.1 - 9.8e-22 78.2 0.0 1.5e-21 77.7 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) adh_short PF00106.25 OAP65106.1 - 7.4e-33 113.7 0.0 9.6e-33 113.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP65106.1 - 3e-22 79.3 0.0 4.2e-22 78.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP65106.1 - 3e-07 30.5 0.0 4.3e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 KR domain Glyco_tran_WecB PF03808.13 OAP65106.1 - 0.029 14.3 0.1 0.15 12.0 0.0 2.1 2 1 1 3 3 3 0 Glycosyl transferase WecB/TagA/CpsF family Zn_clus PF00172.18 OAP65107.1 - 4.3e-07 29.9 10.5 1.3e-06 28.4 10.5 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pro_CA PF00484.19 OAP65108.1 - 1.1e-10 42.1 0.1 2.2e-10 41.1 0.1 1.6 1 1 0 1 1 1 1 Carbonic anhydrase Zn_clus PF00172.18 OAP65109.1 - 1.7e-09 37.6 11.5 3.7e-09 36.6 11.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 OAP65109.1 - 6.4e-05 21.9 0.0 0.0001 21.3 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short_C2 PF13561.6 OAP65111.1 - 1.1e-40 139.6 0.4 1.3e-40 139.4 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP65111.1 - 1.8e-33 115.7 0.4 2.3e-33 115.3 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAP65111.1 - 6.2e-06 26.2 0.3 1.1e-05 25.5 0.3 1.4 1 1 0 1 1 1 1 KR domain UbiD PF01977.16 OAP65112.1 - 6.2e-121 404.1 0.0 7.2e-121 403.9 0.0 1.0 1 0 0 1 1 1 1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase Flavoprotein PF02441.19 OAP65113.1 - 9.2e-25 87.2 0.0 1.2e-24 86.9 0.0 1.1 1 0 0 1 1 1 1 Flavoprotein DIOX_N PF14226.6 OAP65114.1 - 2.9e-30 105.4 0.0 4.1e-30 104.9 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OAP65114.1 - 1.1e-24 86.8 0.0 4.7e-24 84.8 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DUF3433 PF11915.8 OAP65115.1 - 2.1e-18 66.6 6.2 2.2e-13 50.5 0.8 3.3 3 1 0 3 3 3 2 Protein of unknown function (DUF3433) Thiolase_N PF00108.23 OAP65116.1 - 6.9e-12 45.3 0.0 2.1e-09 37.1 0.0 2.3 2 0 0 2 2 2 2 Thiolase, N-terminal domain Thiolase_C PF02803.18 OAP65116.1 - 4.8e-09 35.9 0.1 1.8e-08 34.0 0.1 2.0 1 1 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III PF08545.10 OAP65116.1 - 1e-06 28.5 0.0 0.00014 21.6 0.0 2.5 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.26 OAP65116.1 - 0.019 14.6 0.1 0.042 13.4 0.1 1.6 1 1 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 OAP65116.1 - 0.035 14.1 0.1 0.56 10.2 0.0 2.4 2 0 0 2 2 2 0 Beta-ketoacyl synthase, C-terminal domain adh_short_C2 PF13561.6 OAP65117.1 - 3.5e-34 118.4 1.6 2e-33 115.9 1.6 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP65117.1 - 5.5e-31 107.5 0.9 1.3e-30 106.3 0.9 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAP65117.1 - 0.00035 20.5 0.3 0.00035 20.5 0.3 1.5 2 0 0 2 2 2 1 KR domain Sacchrp_dh_NADP PF03435.18 OAP65117.1 - 0.089 13.1 0.9 0.2 11.9 0.6 1.7 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Sugar_tr PF00083.24 OAP65118.1 - 1.6e-12 47.1 0.1 1.9e-12 46.8 0.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Fungal_trans_2 PF11951.8 OAP65120.1 - 0.00059 18.8 0.1 0.00083 18.3 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Chal_sti_synt_C PF02797.15 OAP65120.1 - 0.046 13.7 0.0 0.092 12.7 0.0 1.5 1 0 0 1 1 1 0 Chalcone and stilbene synthases, C-terminal domain DUF2140 PF09911.9 OAP65122.1 - 0.17 11.4 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) NPR3 PF03666.13 OAP65123.1 - 2.7 6.7 5.5 3.3 6.4 5.5 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF3433 PF11915.8 OAP65124.1 - 2.1e-31 108.2 16.2 1.4e-25 89.6 2.6 3.4 4 0 0 4 4 4 2 Protein of unknown function (DUF3433) DUF4064 PF13273.6 OAP65124.1 - 0.058 13.7 0.2 0.058 13.7 0.2 3.7 5 0 0 5 5 5 0 Protein of unknown function (DUF4064) Epimerase PF01370.21 OAP65125.1 - 0.00017 21.2 0.0 0.00033 20.2 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Glu_dehyd_C PF16912.5 OAP65125.1 - 0.011 15.3 0.0 0.016 14.7 0.0 1.2 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus FMN_dh PF01070.18 OAP65126.1 - 6.9e-105 350.9 0.0 9.7e-105 350.4 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 OAP65126.1 - 5.1e-06 25.7 0.1 9.1e-06 24.9 0.1 1.4 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 OAP65126.1 - 8.7e-06 25.1 0.1 6.8e-05 22.2 0.0 2.0 2 0 0 2 2 2 1 Conserved region in glutamate synthase His_biosynth PF00977.21 OAP65126.1 - 0.00035 20.1 0.2 0.12 11.8 0.0 3.1 3 1 1 4 4 4 1 Histidine biosynthesis protein ThiG PF05690.14 OAP65126.1 - 0.0092 15.3 0.1 21 4.3 0.0 3.1 2 1 1 3 3 3 2 Thiazole biosynthesis protein ThiG Ribul_P_3_epim PF00834.19 OAP65126.1 - 0.14 11.5 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family PS_Dcarbxylase PF02666.15 OAP65128.1 - 2.4e-80 268.8 0.0 2.4e-78 262.3 0.0 2.0 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase ubiquitin PF00240.23 OAP65129.1 - 1.1e-07 31.5 0.0 2.1e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 OAP65129.1 - 0.00072 20.1 0.0 0.0019 18.8 0.0 1.8 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain DUF2156 PF09924.9 OAP65130.1 - 1e-30 106.8 0.0 1.4e-30 106.3 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2156) DUF4834 PF16118.5 OAP65130.1 - 5 8.1 5.5 0.98 10.4 0.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) UBA_4 PF14555.6 OAP65131.1 - 0.0024 17.6 0.0 0.0047 16.7 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain LysM PF01476.20 OAP65131.1 - 0.026 14.6 0.0 0.049 13.7 0.0 1.5 1 0 0 1 1 1 0 LysM domain zf-RING_10 PF16685.5 OAP65131.1 - 9.3 6.5 11.2 1e+02 3.1 11.2 2.3 1 1 0 1 1 1 0 zinc RING finger of MSL2 adh_short PF00106.25 OAP65132.1 - 5.4e-27 94.5 0.0 6.7e-27 94.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP65132.1 - 7.9e-18 64.9 0.0 1e-17 64.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP65132.1 - 0.00078 19.4 0.0 0.0018 18.2 0.0 1.5 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.10 OAP65132.1 - 0.0017 17.8 0.0 0.0027 17.1 0.0 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) ATPase_gene1 PF09527.10 OAP65132.1 - 0.11 12.7 0.1 0.27 11.4 0.1 1.7 1 1 0 1 1 1 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter SNF2_N PF00176.23 OAP65133.1 - 1.9e-59 201.2 0.5 6.3e-59 199.4 0.4 1.8 1 1 1 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OAP65133.1 - 5.5e-16 58.9 0.0 1.2e-15 57.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.6 OAP65133.1 - 4.9e-08 32.7 3.4 8.9e-08 31.9 3.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAP65133.1 - 5e-07 29.5 5.7 9.1e-07 28.7 5.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAP65133.1 - 6.1e-07 29.4 4.1 1.4e-06 28.3 4.1 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OAP65133.1 - 2.3e-06 27.3 5.6 5e-06 26.3 5.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.15 OAP65133.1 - 5.6e-06 26.5 0.0 1.3e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-RING_2 PF13639.6 OAP65133.1 - 6e-06 26.5 5.6 1.3e-05 25.5 5.6 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 OAP65133.1 - 9.5e-06 25.7 7.3 1.9e-05 24.7 7.3 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 OAP65133.1 - 6e-05 22.9 5.6 0.00011 22.1 5.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 OAP65133.1 - 0.00012 21.9 6.1 0.00026 20.8 6.1 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 AAA_34 PF13872.6 OAP65133.1 - 0.0034 16.3 0.0 0.0091 14.9 0.0 1.6 2 0 0 2 2 2 1 P-loop containing NTP hydrolase pore-1 ERCC3_RAD25_C PF16203.5 OAP65133.1 - 0.048 12.9 0.0 0.086 12.0 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase PhoH PF02562.16 OAP65133.1 - 0.054 12.9 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein zf-RING_4 PF14570.6 OAP65133.1 - 0.083 12.7 4.9 0.19 11.5 4.9 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Gin PF10764.9 OAP65133.1 - 0.26 11.3 1.9 0.52 10.3 1.9 1.5 1 0 0 1 1 1 0 Inhibitor of sigma-G Gin MFS_1 PF07690.16 OAP65134.1 - 7.1e-12 44.9 43.2 7.1e-12 44.9 43.2 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily Glyco_hydro_31 PF01055.26 OAP65135.1 - 2.6e-90 303.7 0.4 3.4e-90 303.4 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 OAP65135.1 - 1.1e-08 35.3 0.0 3.7e-08 33.6 0.0 1.9 1 0 0 1 1 1 1 Galactose mutarotase-like MFS_1 PF07690.16 OAP65136.1 - 1.7e-33 116.0 29.6 1.7e-33 116.0 29.6 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Fungal_trans PF04082.18 OAP65137.1 - 0.1 11.6 0.1 0.18 10.8 0.1 1.4 1 0 0 1 1 1 0 Fungal specific transcription factor domain AMP-binding PF00501.28 OAP65138.1 - 1.1e-70 238.4 0.0 1.4e-70 238.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme adh_short PF00106.25 OAP65139.1 - 1.4e-14 54.0 0.0 6.4e-14 51.9 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP65139.1 - 7.8e-06 25.6 0.0 1.5e-05 24.6 0.0 1.4 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP65139.1 - 9.7e-06 25.6 0.0 1.3e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 KR domain Helo_like_N PF17111.5 OAP65140.1 - 0.13 11.6 2.5 0.22 10.9 2.5 1.4 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins RE_HindIII PF09518.10 OAP65140.1 - 0.25 10.6 3.5 0.39 9.9 3.5 1.2 1 0 0 1 1 1 0 HindIII restriction endonuclease Borrelia_P83 PF05262.11 OAP65140.1 - 0.27 9.7 11.0 0.38 9.2 11.0 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein ABC_membrane_2 PF06472.15 OAP65141.1 - 2.6e-90 302.5 0.5 3.9e-90 301.9 0.5 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 OAP65141.1 - 9.7e-15 55.3 0.0 1.8e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 OAP65141.1 - 0.11 12.3 0.2 0.77 9.6 0.2 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain PLU-1 PF08429.11 OAP65141.1 - 0.11 11.6 0.0 14 4.8 0.1 2.2 2 0 0 2 2 2 0 PLU-1-like protein 2-Hacid_dh_C PF02826.19 OAP65142.1 - 5.5e-54 182.2 0.0 7.4e-54 181.8 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 OAP65142.1 - 2.7e-16 59.4 0.0 3.3e-16 59.2 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 OAP65142.1 - 0.0015 18.7 0.1 0.0033 17.6 0.1 1.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 OAP65142.1 - 0.19 11.8 0.3 1.3 9.1 0.3 2.3 2 1 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ADH_N PF08240.12 OAP65143.1 - 9.5e-25 86.6 0.1 2e-24 85.6 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 OAP65143.1 - 4e-13 49.3 0.9 1.3e-06 28.1 0.2 2.3 2 0 0 2 2 2 2 Glucose dehydrogenase C-terminus ADH_zinc_N PF00107.26 OAP65143.1 - 4.3e-12 46.1 0.2 7.4e-12 45.4 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ThiF PF00899.21 OAP65143.1 - 0.0011 18.4 1.5 0.0019 17.6 1.5 1.3 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 OAP65143.1 - 0.046 13.8 0.1 0.083 13.0 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 OAP65143.1 - 0.058 13.7 0.1 0.1 12.8 0.1 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain FAD_binding_3 PF01494.19 OAP65143.1 - 0.095 11.9 1.2 0.15 11.3 1.2 1.2 1 0 0 1 1 1 0 FAD binding domain NmrA PF05368.13 OAP65144.1 - 2e-37 129.0 0.0 2.5e-37 128.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAP65144.1 - 1.5e-18 67.3 0.1 2e-18 67.0 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAP65144.1 - 1.4e-08 34.5 0.1 4.9e-08 32.7 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OAP65144.1 - 0.0011 18.1 0.0 0.0015 17.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TMEM171 PF15471.6 OAP65144.1 - 0.0076 15.3 0.0 0.014 14.4 0.0 1.4 1 1 0 1 1 1 1 Transmembrane protein family 171 NAD_binding_4 PF07993.12 OAP65144.1 - 0.0092 15.2 0.0 0.27 10.4 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein Semialdhyde_dh PF01118.24 OAP65144.1 - 0.037 14.5 0.0 0.07 13.6 0.0 1.5 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 OAP65144.1 - 0.039 13.4 0.0 0.061 12.7 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase DapB_N PF01113.20 OAP65144.1 - 0.039 14.1 0.0 0.19 11.9 0.0 2.0 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Cyt-b5 PF00173.28 OAP65146.1 - 1.8e-19 69.6 0.9 3.2e-18 65.6 0.0 2.6 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.13 OAP65146.1 - 2.7e-10 40.7 24.2 4.6e-10 39.9 23.6 1.7 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Anth_synt_I_N PF04715.13 OAP65146.1 - 0.013 15.7 0.1 0.024 14.8 0.1 1.4 1 0 0 1 1 1 0 Anthranilate synthase component I, N terminal region YEATS PF03366.16 OAP65147.1 - 1.1e-12 47.7 0.7 2.2e-12 46.8 0.7 1.4 1 0 0 1 1 1 1 YEATS family zf-C3HC4_4 PF15227.6 OAP65147.1 - 1.4e-06 28.4 3.1 1.4e-06 28.4 3.1 2.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 OAP65147.1 - 6.4e-06 26.1 3.2 6.4e-06 26.1 3.2 1.9 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OAP65147.1 - 3e-05 23.7 3.9 3e-05 23.7 3.9 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OAP65147.1 - 8.2e-05 22.4 7.2 0.0007 19.4 2.9 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAP65147.1 - 0.00021 21.1 8.0 0.00094 19.0 8.0 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAP65147.1 - 0.00023 21.0 7.2 0.00078 19.4 7.3 1.9 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 OAP65147.1 - 0.0085 16.4 12.7 0.064 13.6 12.7 2.1 1 1 0 1 1 1 1 Ring finger domain zf-RING_10 PF16685.5 OAP65147.1 - 0.14 12.3 6.0 0.22 11.7 4.0 2.0 2 0 0 2 2 2 0 zinc RING finger of MSL2 Prok-RING_4 PF14447.6 OAP65147.1 - 0.75 9.7 10.6 44 4.0 6.9 3.2 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 zf-piccolo PF05715.13 OAP65147.1 - 2.1 8.5 6.0 1.5 9.0 2.4 2.1 2 0 0 2 2 2 0 Piccolo Zn-finger zf-C3HC4_5 PF17121.5 OAP65147.1 - 5.5 7.0 11.0 5.7 6.9 6.4 2.7 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Glyco_hydro_30 PF02055.16 OAP65149.1 - 1.7e-19 70.0 0.0 2.2e-19 69.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_30C PF17189.4 OAP65149.1 - 6.7e-05 23.0 0.0 0.00029 21.0 0.0 2.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain Fungal_trans PF04082.18 OAP65150.1 - 5.3e-07 28.9 0.2 3.6e-06 26.2 0.2 2.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP65150.1 - 5.7e-06 26.4 9.4 9.9e-06 25.6 9.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short_C2 PF13561.6 OAP65151.1 - 2.7e-49 167.8 0.0 3.1e-49 167.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP65151.1 - 1.4e-45 155.1 0.1 1.8e-45 154.8 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAP65151.1 - 8.9e-11 42.0 0.1 1.2e-10 41.6 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAP65151.1 - 0.0016 17.9 0.1 0.0059 16.1 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 OAP65151.1 - 0.0016 17.6 0.0 0.0021 17.3 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 OAP65151.1 - 0.0025 17.3 0.1 0.0056 16.1 0.1 1.5 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 OAP65151.1 - 0.027 14.4 0.0 0.043 13.7 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding Sugar_tr PF00083.24 OAP65152.1 - 4.1e-85 286.3 18.9 4.8e-85 286.1 18.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP65152.1 - 2.4e-21 76.1 37.1 2.8e-17 62.7 24.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Zn_clus PF00172.18 OAP65153.1 - 0.0012 18.9 12.6 0.004 17.3 12.6 1.9 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAP65153.1 - 0.049 12.6 0.0 0.11 11.4 0.0 1.6 1 0 0 1 1 1 0 Fungal specific transcription factor domain MFS_1 PF07690.16 OAP65154.1 - 1.4e-23 83.4 54.4 2.1e-15 56.5 38.7 3.8 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.13 OAP65154.1 - 2.2e-12 46.2 5.8 2.2e-12 46.2 5.8 2.7 2 1 1 3 3 3 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 OAP65154.1 - 0.0055 15.1 2.2 0.2 9.9 0.0 2.6 2 1 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family DUF3624 PF12292.8 OAP65154.1 - 0.021 15.2 0.0 0.15 12.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3624) PRR18 PF15671.5 OAP65154.1 - 0.049 13.5 0.1 0.069 13.0 0.1 1.2 1 0 0 1 1 1 0 Proline-rich protein family 18 HET PF06985.11 OAP65155.1 - 6e-16 59.1 0.0 1.1e-15 58.2 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Helo_like_N PF17111.5 OAP65157.1 - 4.1e-05 23.1 0.0 6e-05 22.5 0.0 1.4 1 1 0 1 1 1 1 Fungal N-terminal domain of STAND proteins NPV_P10 PF05531.12 OAP65157.1 - 0.029 14.8 4.2 0.62 10.6 0.4 3.1 2 2 2 4 4 4 0 Nucleopolyhedrovirus P10 protein Surfac_D-trimer PF09006.11 OAP65157.1 - 0.032 14.1 0.2 0.11 12.5 0.2 1.9 1 0 0 1 1 1 0 Lung surfactant protein D coiled-coil trimerisation SF-assemblin PF06705.11 OAP65157.1 - 0.068 12.5 0.0 0.32 10.3 0.0 1.8 2 0 0 2 2 2 0 SF-assemblin/beta giardin KLRAQ PF10205.9 OAP65157.1 - 0.2 11.9 0.0 4.4 7.6 0.0 2.2 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein PNISR PF15996.5 OAP65158.1 - 0.032 14.5 7.4 0.044 14.1 7.4 1.1 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR Nop14 PF04147.12 OAP65158.1 - 8.6 4.4 17.9 9.2 4.3 17.9 1.1 1 0 0 1 1 1 0 Nop14-like family GST_N_2 PF13409.6 OAP65159.1 - 2.6e-08 34.1 0.0 4.2e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 OAP65159.1 - 4e-08 33.5 0.0 8.6e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 OAP65159.1 - 0.037 14.2 0.0 0.072 13.3 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OAP65159.1 - 0.076 13.1 1.2 0.14 12.2 0.5 1.8 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Dynein_light PF01221.18 OAP65160.1 - 6.7e-35 119.3 4.6 1.4e-28 99.0 0.6 2.0 2 0 0 2 2 2 2 Dynein light chain type 1 Ground-like PF04155.18 OAP65160.1 - 0.014 16.0 0.2 0.025 15.2 0.2 1.5 1 1 0 1 1 1 0 Ground-like domain RhoGEF67_u1 PF16615.5 OAP65160.1 - 0.06 13.9 0.0 0.097 13.2 0.0 1.3 1 0 0 1 1 1 0 Unstructured region one on RhoGEF 6 and 7 ArAE_2_N PF10337.9 OAP65161.1 - 4.1e-35 121.7 9.2 2.9e-33 115.6 9.2 3.1 1 1 0 1 1 1 1 Putative ER transporter, 6TM, N-terminal FUSC_2 PF13515.6 OAP65161.1 - 4e-15 56.1 12.7 4e-15 56.1 12.7 3.5 3 1 0 3 3 3 1 Fusaric acid resistance protein-like ArAE_2 PF10334.9 OAP65161.1 - 2.3e-06 27.7 0.0 0.051 13.4 0.0 2.7 2 1 0 2 2 2 2 Aromatic acid exporter family member 2 Phage_Gp17 PF17549.2 OAP65161.1 - 0.12 12.4 0.3 0.22 11.5 0.3 1.4 1 0 0 1 1 1 0 Gene Product 17 ALMT PF11744.8 OAP65161.1 - 8.7 5.0 14.4 4.8 5.9 0.0 3.1 2 1 0 2 2 2 0 Aluminium activated malate transporter HET PF06985.11 OAP65162.1 - 2e-19 70.4 0.0 3.6e-19 69.6 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Aa_trans PF01490.18 OAP65163.1 - 2.7e-32 112.0 35.9 2.7e-32 112.0 35.9 2.1 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein Transket_pyr PF02779.24 OAP65164.1 - 2.2e-41 141.5 0.0 4e-41 140.6 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 OAP65164.1 - 1.3e-34 118.8 0.0 3.6e-34 117.3 0.0 1.7 2 0 0 2 2 2 1 Transketolase, C-terminal domain PFOR_II PF17147.4 OAP65164.1 - 0.0079 16.5 0.0 0.015 15.6 0.0 1.5 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II E1_dh PF00676.20 OAP65165.1 - 6.1e-89 297.9 0.0 7.3e-89 297.7 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 OAP65165.1 - 1.3e-05 25.1 0.1 7.7e-05 22.5 0.1 2.1 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 OAP65165.1 - 0.0027 17.0 0.0 0.005 16.1 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Elongin_A PF06881.11 OAP65165.1 - 0.7 10.5 4.1 4.6 7.8 4.5 1.9 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A 2-oxoacid_dh PF00198.23 OAP65166.1 - 2.7e-69 233.2 0.6 4e-68 229.4 0.2 2.1 2 0 0 2 2 2 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 OAP65166.1 - 9.5e-19 67.0 0.0 2.4e-18 65.7 0.0 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 OAP65166.1 - 5e-13 49.2 0.1 1.1e-12 48.0 0.1 1.7 1 0 0 1 1 1 1 e3 binding domain Pectate_lyase_3 PF12708.7 OAP65167.1 - 5.8e-86 287.8 11.6 2e-75 253.3 4.9 2.9 3 0 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 OAP65167.1 - 3.2e-09 36.3 0.8 0.00038 20.1 0.0 2.6 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase PAE PF03283.13 OAP65168.1 - 0.044 12.9 0.0 0.073 12.2 0.0 1.3 1 0 0 1 1 1 0 Pectinacetylesterase DIOX_N PF14226.6 OAP65169.1 - 0.043 14.6 0.4 0.1 13.4 0.1 1.8 2 0 0 2 2 2 0 non-haem dioxygenase in morphine synthesis N-terminal Pkinase PF00069.25 OAP65170.1 - 2.8e-35 122.0 0.0 4.1e-35 121.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP65170.1 - 6.5e-21 74.8 0.0 9.6e-21 74.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OAP65170.1 - 0.014 15.3 0.1 0.074 13.0 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OAP65170.1 - 0.044 12.6 0.0 0.066 12.0 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase RRM_1 PF00076.22 OAP65171.1 - 2e-74 245.4 0.0 3.8e-19 68.3 0.0 5.5 5 1 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OAP65171.1 - 6.9e-09 35.4 0.0 0.058 13.0 0.0 5.0 4 1 0 5 5 5 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OAP65171.1 - 1.9e-06 27.6 0.0 0.0015 18.4 0.0 3.9 5 0 0 5 5 5 1 Occluded RNA-recognition motif RRM_7 PF16367.5 OAP65171.1 - 6.9e-05 22.9 0.0 8.2 6.6 0.0 4.2 4 0 0 4 4 4 2 RNA recognition motif Smg4_UPF3 PF03467.15 OAP65171.1 - 0.01 15.9 0.6 1.7 8.6 0.0 3.6 4 0 0 4 4 4 0 Smg-4/UPF3 family RRM_3 PF08777.11 OAP65171.1 - 0.016 15.2 0.0 48 4.1 0.0 4.3 4 0 0 4 4 4 0 RNA binding motif Nup35_RRM_2 PF14605.6 OAP65171.1 - 0.026 14.5 0.0 10 6.2 0.0 4.0 5 0 0 5 5 5 0 Nup53/35/40-type RNA recognition motif RRM_Rrp7 PF17799.1 OAP65171.1 - 0.027 14.3 0.4 7.2 6.4 0.0 3.6 4 0 0 4 4 4 0 Rrp7 RRM-like N-terminal domain TEA PF01285.18 OAP65172.1 - 5.2e-27 93.7 0.1 1.2e-26 92.6 0.1 1.6 1 0 0 1 1 1 1 TEA/ATTS domain Histidinol_dh PF00815.20 OAP65173.1 - 6.4e-138 460.2 0.0 7.7e-138 459.9 0.0 1.0 1 0 0 1 1 1 1 Histidinol dehydrogenase SprA-related PF12118.8 OAP65174.1 - 9.7 5.2 14.0 13 4.8 14.0 1.1 1 0 0 1 1 1 0 SprA-related family NAD_binding_6 PF08030.12 OAP65175.1 - 2.2e-19 70.1 0.0 3.4e-19 69.5 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 OAP65175.1 - 2.5e-19 69.6 15.0 5.7e-19 68.5 15.0 1.7 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 OAP65175.1 - 1.8e-12 47.3 0.0 3.6e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain DUF1270 PF06900.11 OAP65175.1 - 2.7 8.4 11.5 0.72 10.3 0.9 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1270) AIDA PF16168.5 OAP65176.1 - 0.036 14.2 3.3 0.085 12.9 3.3 1.7 1 0 0 1 1 1 0 Adhesin of bacterial autotransporter system, probable stalk Glyco_hydro_32N PF00251.20 OAP65177.1 - 1.2e-79 268.0 2.9 1.5e-79 267.7 2.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 OAP65177.1 - 1.5e-07 31.5 0.1 2.8e-07 30.7 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Sugar_tr PF00083.24 OAP65178.1 - 8.6e-127 423.7 24.8 1e-126 423.5 24.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP65178.1 - 2.8e-17 62.7 40.1 4.7e-13 48.8 17.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily zf_UBZ PF18439.1 OAP65179.1 - 6.1e-12 44.9 3.4 1.2e-11 44.0 3.4 1.5 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger VWA_2 PF13519.6 OAP65179.1 - 3.8e-06 27.5 0.9 3.4e-05 24.4 0.0 2.8 3 0 0 3 3 3 1 von Willebrand factor type A domain VWA PF00092.28 OAP65179.1 - 0.0012 19.1 0.0 0.006 16.8 0.0 2.2 2 1 0 2 2 2 1 von Willebrand factor type A domain YTH PF04146.15 OAP65180.1 - 2.2e-43 148.1 0.0 3.7e-43 147.3 0.0 1.4 1 0 0 1 1 1 1 YT521-B-like domain RRM_1 PF00076.22 OAP65180.1 - 0.04 13.8 0.0 0.067 13.0 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SR-25 PF10500.9 OAP65180.1 - 1.8 8.1 8.1 4.6 6.8 8.1 1.6 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Es2 PF09751.9 OAP65182.1 - 0.72 9.5 4.2 0.66 9.7 0.3 2.0 1 1 0 2 2 2 0 Nuclear protein Es2 MRI PF15325.6 OAP65182.1 - 1.5 10.0 4.1 1.9 9.6 0.2 2.3 2 0 0 2 2 2 0 Modulator of retrovirus infection SSF PF00474.17 OAP65183.1 - 1.6e-19 70.1 27.6 2.3e-19 69.6 27.6 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family DUF962 PF06127.11 OAP65183.1 - 0.089 12.9 1.0 6.4 6.9 0.1 3.7 1 1 1 2 2 2 0 Protein of unknown function (DUF962) Ibs_toxin PF13956.6 OAP65183.1 - 0.29 11.2 3.4 0.94 9.6 3.4 1.9 1 0 0 1 1 1 0 Toxin Ibs, type I toxin-antitoxin system CheZ PF04344.13 OAP65184.1 - 0.002 18.1 0.7 0.006 16.5 0.5 2.0 1 1 0 1 1 1 1 Chemotaxis phosphatase, CheZ D-ser_dehydrat PF14031.6 OAP65185.1 - 3.7e-24 85.2 0.0 7.6e-24 84.2 0.0 1.6 1 0 0 1 1 1 1 Putative serine dehydratase domain Ala_racemase_N PF01168.20 OAP65185.1 - 5.6e-17 62.1 0.0 8.1e-17 61.6 0.0 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain DUF3295 PF11702.8 OAP65187.1 - 2.9e-116 389.8 31.7 3.4e-116 389.6 31.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3295) DUF1752 PF08550.10 OAP65187.1 - 2.5e-12 46.4 0.7 5e-12 45.4 0.7 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) DNA_pol_phi PF04931.13 OAP65187.1 - 8.4 4.4 11.2 13 3.7 11.2 1.2 1 0 0 1 1 1 0 DNA polymerase phi zf-CHY PF05495.12 OAP65188.1 - 3.1e-10 40.4 13.1 3.1e-10 40.4 13.1 3.5 2 1 2 4 4 4 1 CHY zinc finger Pes-10 PF07149.11 OAP65188.1 - 0.18 10.8 3.0 0.29 10.1 3.0 1.2 1 0 0 1 1 1 0 Pes-10 zinc_ribbon_15 PF17032.5 OAP65188.1 - 0.44 11.3 16.7 0.79 10.5 0.0 3.4 3 0 0 3 3 3 0 zinc-ribbon family Ribosomal_L40e PF01020.17 OAP65188.1 - 1.7 8.6 5.0 4.7 7.2 1.1 2.7 2 0 0 2 2 2 0 Ribosomal L40e family Cytochrome_C7 PF14522.6 OAP65188.1 - 7.9 6.6 15.8 25 5.0 0.0 3.5 3 0 0 3 3 3 0 Cytochrome c7 and related cytochrome c VIR_N PF15912.5 OAP65189.1 - 1.2 8.7 3.8 3.6 7.1 3.8 1.7 1 0 0 1 1 1 0 Virilizer, N-terminal Cpn60_TCP1 PF00118.24 OAP65190.1 - 1.1e-158 528.9 5.7 1.3e-158 528.7 5.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Resolvase PF00239.21 OAP65190.1 - 0.085 13.0 0.4 0.59 10.2 0.1 2.4 2 0 0 2 2 2 0 Resolvase, N terminal domain Enolase_N PF03952.16 OAP65190.1 - 0.5 10.5 2.6 26 5.0 0.2 3.2 3 0 0 3 3 3 0 Enolase, N-terminal domain Chromo PF00385.24 OAP65192.1 - 2.4e-14 53.0 1.0 2.4e-14 53.0 1.0 2.3 3 0 0 3 3 3 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.19 OAP65192.1 - 7.9e-10 38.7 0.1 1.6e-08 34.5 0.0 2.3 2 0 0 2 2 2 1 Chromo shadow domain Nop14 PF04147.12 OAP65192.1 - 2.5 6.2 29.6 0.53 8.4 23.1 2.0 2 0 0 2 2 2 0 Nop14-like family Myb_DNA-bind_2 PF08914.11 OAP65193.1 - 1.1e-15 57.6 0.6 3.1e-15 56.1 0.6 1.9 1 0 0 1 1 1 1 Rap1 Myb domain Rap1_C PF11626.8 OAP65193.1 - 5.7e-12 45.5 0.2 5.7e-11 42.3 0.0 2.7 2 1 0 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain GATA PF00320.27 OAP65193.1 - 2.5e-06 27.0 1.8 4.7e-06 26.1 1.8 1.5 1 0 0 1 1 1 1 GATA zinc finger Rap1-DNA-bind PF09197.10 OAP65193.1 - 0.0013 19.3 2.8 0.0089 16.6 0.5 2.9 2 0 0 2 2 2 1 Rap1, DNA-binding ArfGap PF01412.18 OAP65193.1 - 0.0038 17.3 1.5 0.013 15.6 1.5 1.9 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf BRCT_2 PF16589.5 OAP65193.1 - 0.16 12.4 0.0 0.36 11.3 0.0 1.7 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain Myb_DNA-binding PF00249.31 OAP65193.1 - 0.23 11.7 3.9 3.3 8.0 0.0 3.6 4 0 0 4 4 4 0 Myb-like DNA-binding domain ICAP-1_inte_bdg PF10480.9 OAP65193.1 - 0.87 9.6 4.6 1.9 8.4 4.6 1.5 1 0 0 1 1 1 0 Beta-1 integrin binding protein Cyt-b5 PF00173.28 OAP65194.1 - 7.9e-23 80.4 0.2 1.1e-22 80.0 0.2 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain VHS PF00790.19 OAP65195.1 - 8.6e-33 113.2 2.6 1.4e-32 112.5 2.6 1.4 1 0 0 1 1 1 1 VHS domain SH3_1 PF00018.28 OAP65195.1 - 1.9e-16 59.4 0.0 4.5e-16 58.2 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 OAP65195.1 - 7.2e-15 54.6 0.1 1.5e-14 53.6 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 OAP65195.1 - 2.6e-14 52.6 0.0 4.8e-14 51.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain GAT PF03127.14 OAP65195.1 - 7.6e-10 39.0 2.4 8e-10 38.9 0.7 1.9 2 0 0 2 2 2 1 GAT domain UIM PF02809.20 OAP65195.1 - 0.12 12.4 3.6 0.27 11.3 3.6 1.6 1 0 0 1 1 1 0 Ubiquitin interaction motif DUF445 PF04286.12 OAP65195.1 - 1.2 8.9 4.1 0.21 11.4 0.5 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF445) Pkinase PF00069.25 OAP65196.1 - 5.4e-73 245.6 0.0 7.4e-73 245.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP65196.1 - 2.7e-46 157.9 0.0 4.1e-46 157.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 OAP65196.1 - 5.2e-18 65.2 0.0 1.7e-17 63.5 0.0 2.0 1 0 0 1 1 1 1 P21-Rho-binding domain Pkinase_fungal PF17667.1 OAP65196.1 - 7.2e-07 28.3 0.0 1.8e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 OAP65196.1 - 1.6e-06 27.7 0.0 2.7e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OAP65196.1 - 0.032 13.2 0.8 0.098 11.6 0.8 1.9 1 1 0 1 1 1 0 Haspin like kinase domain DSHCT PF08148.12 OAP65196.1 - 0.036 13.7 0.0 0.079 12.6 0.0 1.5 1 0 0 1 1 1 0 DSHCT (NUC185) domain Kdo PF06293.14 OAP65196.1 - 0.11 11.9 1.0 0.33 10.3 0.1 2.0 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family COX15-CtaA PF02628.15 OAP65197.1 - 3.5e-114 381.3 7.7 5.8e-114 380.5 7.7 1.4 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein KCH PF16944.5 OAP65197.1 - 4.4e-101 337.9 1.2 7.3e-101 337.2 1.2 1.4 1 0 0 1 1 1 1 Fungal potassium channel Oxidored_FMN PF00724.20 OAP65198.1 - 2.3e-60 204.7 0.0 2.8e-60 204.4 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family HET PF06985.11 OAP65200.1 - 1.7e-17 64.1 0.0 4.4e-17 62.8 0.0 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) BTB PF00651.31 OAP65201.1 - 5.6e-08 33.0 0.0 9.8e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain MATH PF00917.26 OAP65201.1 - 0.037 14.2 0.0 0.35 11.0 0.0 2.3 2 0 0 2 2 2 0 MATH domain DUF747 PF05346.11 OAP65202.1 - 3.4e-119 398.0 10.5 4.5e-119 397.6 10.5 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family tRNA-synt_2 PF00152.20 OAP65203.1 - 1.1e-76 257.9 0.4 1.6e-76 257.4 0.4 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 OAP65203.1 - 8.9e-12 44.8 0.0 2.7e-11 43.3 0.0 1.9 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 OAP65203.1 - 5.4e-05 22.8 0.2 0.29 10.6 0.0 2.6 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) MAPEG PF01124.18 OAP65204.1 - 2e-24 86.0 2.0 2.4e-24 85.7 2.0 1.1 1 0 0 1 1 1 1 MAPEG family NTP_transferase PF00483.23 OAP65205.1 - 1.3e-31 110.1 0.0 1.9e-31 109.6 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 OAP65205.1 - 1.9e-09 36.9 4.8 4.1e-06 26.3 0.0 3.5 3 0 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 OAP65205.1 - 8.2e-08 32.8 0.0 1.2e-07 32.2 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.19 OAP65205.1 - 0.028 14.2 0.0 0.049 13.4 0.0 1.3 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Pyrid_ox_like PF16242.5 OAP65206.1 - 1.2e-22 80.1 0.2 1.8e-22 79.6 0.2 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like Putative_PNPOx PF01243.20 OAP65206.1 - 3.2e-06 27.2 0.0 5.2e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF155 PF02582.14 OAP65207.1 - 6.8e-53 179.4 0.1 1e-52 178.8 0.1 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 E1_dh PF00676.20 OAP65208.1 - 2e-112 375.0 0.1 2.4e-112 374.8 0.1 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 OAP65208.1 - 0.00014 21.2 0.0 0.0002 20.6 0.0 1.2 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Pkinase PF00069.25 OAP65209.1 - 1.5e-73 247.4 0.0 2.1e-73 247.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP65209.1 - 3.6e-35 121.5 0.0 5.6e-35 120.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Methyltransf_11 PF08241.12 OAP65209.1 - 0.00099 19.7 0.0 0.0023 18.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAP65209.1 - 0.0033 18.1 0.0 0.0066 17.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Haspin_kinase PF12330.8 OAP65209.1 - 0.0089 15.0 0.0 0.58 9.0 0.0 2.3 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 OAP65209.1 - 0.066 13.1 1.7 0.076 12.9 0.1 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 OAP65209.1 - 0.081 12.3 0.3 0.17 11.2 0.3 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family GFA PF04828.14 OAP65210.1 - 8.1e-20 71.0 0.1 1.2e-19 70.4 0.1 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme SAP PF02037.27 OAP65211.1 - 3.5e-12 45.8 0.0 5.8e-12 45.1 0.0 1.4 1 0 0 1 1 1 1 SAP domain Tho1_MOS11_C PF18592.1 OAP65211.1 - 0.0018 18.0 3.9 0.01 15.6 1.1 2.9 2 1 1 3 3 3 2 Tho1/MOS11 C-terminal domain FANC_SAP PF18081.1 OAP65211.1 - 0.012 15.8 0.1 0.032 14.4 0.1 1.8 1 0 0 1 1 1 0 Fanconi anemia-associated nuclease SAP domain HeH PF12949.7 OAP65211.1 - 0.15 11.8 0.2 0.31 10.8 0.2 1.5 1 1 0 1 1 1 0 HeH/LEM domain DUF2868 PF11067.8 OAP65211.1 - 0.38 10.2 4.5 0.51 9.8 4.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) DUF2477 PF10631.9 OAP65211.1 - 9.6 6.9 7.0 5.7 7.6 4.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2477) MFS_1 PF07690.16 OAP65212.1 - 6.6e-31 107.5 20.6 6.6e-31 107.5 20.6 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily UPF0126 PF03458.13 OAP65212.1 - 0.022 14.6 0.8 0.022 14.6 0.8 3.5 3 2 0 3 3 3 0 UPF0126 domain DUF2127 PF09900.9 OAP65212.1 - 2.7 8.2 10.1 6.7 7.0 0.3 4.0 4 0 0 4 4 4 0 Predicted membrane protein (DUF2127) Hep_59 PF07052.11 OAP65213.1 - 2.3e-11 44.4 0.0 2.3e-11 44.4 0.0 2.7 3 1 0 3 3 3 1 Hepatocellular carcinoma-associated antigen 59 DUF1722 PF08349.11 OAP65213.1 - 0.041 14.2 0.1 0.22 11.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) KOW PF00467.29 OAP65213.1 - 0.049 13.6 0.2 0.049 13.6 0.2 1.8 2 0 0 2 2 2 0 KOW motif Ribosomal_L12 PF00542.19 OAP65214.1 - 3e-21 75.5 4.1 3e-21 75.5 4.1 1.6 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain SpoVIF PF14069.6 OAP65214.1 - 0.086 12.6 0.1 0.13 12.0 0.1 1.4 1 1 0 1 1 1 0 Stage VI sporulation protein F P5CR_dimer PF14748.6 OAP65215.1 - 3e-33 114.2 3.0 3e-33 114.2 3.0 1.8 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 OAP65215.1 - 1.8e-12 47.7 0.2 1.8e-10 41.3 0.0 2.7 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent CTK3 PF12243.8 OAP65216.1 - 4.6e-40 136.5 0.0 6.7e-40 135.9 0.0 1.2 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.8 OAP65216.1 - 3.9e-16 58.9 8.9 3.9e-16 58.9 8.9 1.8 2 0 0 2 2 2 1 CTD kinase subunit gamma CTK3 C-terminus Hat1_N PF10394.9 OAP65217.1 - 4.3e-42 144.1 0.0 7e-42 143.4 0.0 1.4 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Zip PF02535.22 OAP65218.1 - 5.9e-37 127.6 20.9 1.9e-28 99.6 12.0 3.0 2 1 0 2 2 2 2 ZIP Zinc transporter DUF4079 PF13301.6 OAP65218.1 - 0.017 15.3 2.7 0.087 13.0 0.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF4079) DUF3899 PF13038.6 OAP65218.1 - 0.017 15.6 0.7 2.3 8.8 0.0 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF3899) DUF4395 PF14340.6 OAP65218.1 - 0.04 14.2 4.3 1.9 8.8 0.1 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF4395) PDR_assoc PF08370.11 OAP65218.1 - 0.057 13.2 0.2 0.24 11.1 0.0 2.2 2 0 0 2 2 2 0 Plant PDR ABC transporter associated BNIP3 PF06553.12 OAP65218.1 - 0.065 12.9 0.6 0.12 12.1 0.6 1.3 1 0 0 1 1 1 0 BNIP3 WD40 PF00400.32 OAP65219.1 - 1.3e-39 133.4 24.6 3.3e-07 30.9 0.1 7.7 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAP65219.1 - 3.1e-10 40.2 1.8 0.033 14.5 0.0 5.7 1 1 6 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OAP65219.1 - 4.7e-08 32.1 6.8 0.26 9.9 0.1 5.8 1 1 5 6 6 6 4 Nucleoporin Nup120/160 WD40_like PF17005.5 OAP65219.1 - 2.8e-07 30.2 0.0 0.0055 16.1 0.0 3.0 1 1 3 4 4 4 3 WD40-like domain BBS2_Mid PF14783.6 OAP65219.1 - 0.016 15.2 0.3 21 5.2 0.0 3.9 4 2 2 6 6 6 0 Ciliary BBSome complex subunit 2, middle region PQQ_2 PF13360.6 OAP65219.1 - 0.041 13.5 4.4 0.094 12.3 1.4 2.7 1 1 0 2 2 2 0 PQQ-like domain Mcl1_mid PF12341.8 OAP65219.1 - 0.25 10.7 1.4 5.6 6.2 0.0 2.9 1 1 0 2 2 2 0 Minichromosome loss protein, Mcl1, middle region Mito_carr PF00153.27 OAP65220.1 - 6.7e-49 163.8 2.9 7e-17 61.1 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Fungal_trans PF04082.18 OAP65221.1 - 7e-09 35.1 0.1 1.9e-08 33.7 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP65221.1 - 2.6e-08 33.9 7.6 4.9e-08 33.0 7.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Spt20 PF12090.8 OAP65221.1 - 0.86 9.2 5.9 2.4 7.7 5.9 1.7 1 0 0 1 1 1 0 Spt20 family DUF1996 PF09362.10 OAP65222.1 - 3.1e-69 233.5 0.6 4.2e-69 233.1 0.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Homeobox_KN PF05920.11 OAP65224.1 - 3.6e-22 78.0 0.7 9.8e-22 76.6 0.7 1.8 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 OAP65224.1 - 1.3e-08 34.5 0.5 2.9e-08 33.4 0.5 1.6 1 0 0 1 1 1 1 Homeodomain FAD_binding_1 PF00667.20 OAP65225.1 - 4.9e-45 153.8 0.0 8.1e-45 153.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 OAP65225.1 - 5.3e-09 36.7 0.0 1.3e-08 35.4 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain GrpB PF04229.14 OAP65226.1 - 4.4e-50 170.0 0.0 5.2e-50 169.8 0.0 1.1 1 0 0 1 1 1 1 GrpB protein Fungal_trans PF04082.18 OAP65227.1 - 7e-13 48.2 0.2 1e-12 47.7 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain NAD_binding_10 PF13460.6 OAP65227.1 - 2.6e-08 34.0 0.1 6.7e-07 29.4 0.0 3.1 2 1 0 2 2 2 1 NAD(P)H-binding Zn_clus PF00172.18 OAP65227.1 - 1.2e-07 31.7 5.0 1.2e-07 31.7 5.0 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NAD_binding_4 PF07993.12 OAP65227.1 - 4.9e-05 22.6 0.0 7.9e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 OAP65227.1 - 0.00049 19.6 0.0 0.00088 18.8 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 OAP65227.1 - 0.019 14.1 0.0 0.03 13.5 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Med20 PF08612.11 OAP65228.1 - 5.9e-22 78.2 0.0 6.7e-22 78.0 0.0 1.1 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex Glyco_hydro_47 PF01532.20 OAP65229.1 - 3.2e-184 613.1 0.0 9.8e-184 611.5 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 47 Glyco_hydro_127 PF07944.12 OAP65229.1 - 0.0034 16.0 0.1 0.26 9.7 0.0 2.1 2 0 0 2 2 2 2 Beta-L-arabinofuranosidase, GH127 Glyco_hydro_88 PF07470.13 OAP65229.1 - 0.031 13.3 0.3 0.71 8.9 0.0 2.4 2 0 0 2 2 2 0 Glycosyl Hydrolase Family 88 EF-1_beta_acid PF10587.9 OAP65229.1 - 0.24 11.9 0.7 0.51 10.8 0.7 1.5 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region CTD_bind PF04818.13 OAP65230.1 - 2.4e-18 66.7 0.0 5.8e-18 65.5 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase II-binding domain. CREPT PF16566.5 OAP65230.1 - 0.1 12.8 0.9 0.21 11.7 0.9 1.5 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour Clathrin_lg_ch PF01086.17 OAP65232.1 - 1.3e-68 231.5 2.3 1.5e-68 231.3 2.3 1.0 1 0 0 1 1 1 1 Clathrin light chain CdiI_2 PF18593.1 OAP65233.1 - 0.02 15.6 0.0 0.94 10.2 0.0 3.0 2 0 0 2 2 2 0 CdiI immunity protein NYD-SP28_assoc PF14775.6 OAP65233.1 - 0.19 11.9 3.4 0.2 11.8 0.8 2.5 2 0 0 2 2 2 0 Sperm tail C-terminal domain ATG16 PF08614.11 OAP65233.1 - 1 9.5 17.1 0.34 11.1 3.4 3.3 3 1 0 3 3 3 0 Autophagy protein 16 (ATG16) Ank_4 PF13637.6 OAP65234.1 - 0.0031 18.0 0.1 2 9.1 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Methyltransf_25 PF13649.6 OAP65234.1 - 0.011 16.4 0.0 0.022 15.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Ank PF00023.30 OAP65234.1 - 0.025 15.0 0.0 0.074 13.5 0.0 1.9 1 0 0 1 1 1 0 Ankyrin repeat adh_short PF00106.25 OAP65235.1 - 5.2e-52 176.1 1.3 6.3e-52 175.9 1.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP65235.1 - 1.6e-48 165.3 0.9 2.6e-48 164.6 0.9 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP65235.1 - 1.2e-09 38.4 0.6 2.1e-09 37.5 0.6 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAP65235.1 - 0.0028 17.1 0.3 0.018 14.5 0.2 2.3 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family VBS PF08913.10 OAP65235.1 - 0.11 12.9 0.3 0.26 11.8 0.3 1.6 1 1 0 1 1 1 0 Vinculin Binding Site Indigoidine_A PF04227.12 OAP65236.1 - 4.3e-120 400.5 0.2 7e-120 399.8 0.2 1.3 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.24 OAP65236.1 - 7.3e-22 78.0 0.2 4.6e-13 49.1 0.1 2.7 3 0 0 3 3 3 2 pfkB family carbohydrate kinase SnoaL_2 PF12680.7 OAP65237.1 - 1.9e-10 41.3 0.1 7e-10 39.5 0.0 2.0 2 0 0 2 2 2 1 SnoaL-like domain SnoaL PF07366.12 OAP65237.1 - 3.1e-06 27.0 0.0 5.7e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase DUF3328 PF11807.8 OAP65240.1 - 1.1e-53 182.2 0.0 1.4e-53 181.9 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) SIS PF01380.22 OAP65241.1 - 8.9e-11 41.8 0.4 4.6e-10 39.5 0.4 2.0 1 1 0 1 1 1 1 SIS domain zf-C2H2_jaz PF12171.8 OAP65242.1 - 9.1e-05 22.6 0.0 0.00014 22.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OAP65242.1 - 0.00086 19.6 0.2 0.0013 19.0 0.2 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type OrsD PF12013.8 OAP65242.1 - 0.0034 17.8 0.0 0.0094 16.4 0.0 1.7 1 0 0 1 1 1 1 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2_2 PF12756.7 OAP65242.1 - 0.036 14.4 0.2 0.09 13.1 0.2 1.6 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Fzo_mitofusin PF04799.13 OAP65242.1 - 0.15 11.6 0.2 0.24 10.9 0.2 1.4 1 0 0 1 1 1 0 fzo-like conserved region SPOC PF07744.13 OAP65243.1 - 8.6e-20 71.2 0.0 1.6e-19 70.3 0.0 1.4 1 0 0 1 1 1 1 SPOC domain TFIIS_M PF07500.14 OAP65243.1 - 2.2e-19 70.0 0.1 3.4e-19 69.4 0.1 1.3 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain PHD PF00628.29 OAP65243.1 - 2.5e-09 36.9 10.7 4.6e-09 36.0 10.7 1.5 1 0 0 1 1 1 1 PHD-finger zinc_ribbon_10 PF10058.9 OAP65243.1 - 0.00025 20.7 6.1 0.00052 19.7 6.1 1.5 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein PHD_2 PF13831.6 OAP65243.1 - 0.048 13.2 5.0 0.1 12.2 5.0 1.5 1 0 0 1 1 1 0 PHD-finger WW PF00397.26 OAP65244.1 - 9.8e-13 48.0 6.6 3.6e-09 36.5 4.5 2.6 2 0 0 2 2 2 2 WW domain FF PF01846.19 OAP65244.1 - 1.5e-12 47.5 3.7 5.9e-10 39.2 0.0 2.6 2 0 0 2 2 2 2 FF domain Hid1 PF12722.7 OAP65244.1 - 0.43 8.7 3.3 0.68 8.0 3.3 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Proteasome PF00227.26 OAP65245.1 - 2.2e-60 203.4 0.0 2.8e-60 203.1 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 OAP65245.1 - 3e-13 49.2 0.1 8.7e-13 47.7 0.1 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Nitrate_red_gam PF02665.14 OAP65245.1 - 0.045 13.3 0.0 0.065 12.8 0.0 1.2 1 0 0 1 1 1 0 Nitrate reductase gamma subunit DUF5624 PF18538.1 OAP65245.1 - 0.099 12.7 0.2 0.29 11.2 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5624) HET PF06985.11 OAP65246.1 - 1.3e-12 48.3 0.0 2e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Carla_C4 PF01623.17 OAP65247.1 - 0.016 15.1 0.2 0.016 15.1 0.2 2.2 2 0 0 2 2 2 0 Carlavirus putative nucleic acid binding protein ADH_zinc_N_2 PF13602.6 OAP65248.1 - 5.1e-28 98.8 2.4 2.6e-27 96.5 1.1 2.5 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 OAP65248.1 - 2.9e-15 56.4 2.0 3.1e-15 56.3 0.2 2.1 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAP65248.1 - 0.00029 20.7 0.0 0.0056 16.6 0.0 2.6 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain Patatin PF01734.22 OAP65249.1 - 4.4e-20 72.7 0.3 1.4e-19 71.1 0.0 2.0 2 1 0 2 2 2 1 Patatin-like phospholipase DEAD PF00270.29 OAP65250.1 - 5.4e-42 143.5 0.1 1.8e-41 141.8 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAP65250.1 - 2.5e-28 98.6 0.2 6.3e-28 97.3 0.1 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain UTP25 PF06862.12 OAP65250.1 - 1.5e-06 27.3 0.2 3.2e-06 26.2 0.1 1.5 2 0 0 2 2 2 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 ResIII PF04851.15 OAP65250.1 - 0.0003 20.8 0.0 0.0011 19.0 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 OAP65250.1 - 0.009 16.3 1.2 0.027 14.7 0.5 2.3 2 1 0 2 2 2 1 AAA domain 3HCDH_N PF02737.18 OAP65250.1 - 0.082 12.8 0.1 0.19 11.6 0.1 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lyase_1 PF00206.20 OAP65251.1 - 1.2e-24 87.3 0.1 2.3e-24 86.3 0.0 1.4 2 0 0 2 2 2 1 Lyase ADSL_C PF10397.9 OAP65251.1 - 1.5e-12 47.9 0.0 4.6e-12 46.3 0.0 1.9 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus Med7 PF05983.11 OAP65252.1 - 1.1e-43 149.6 4.0 1.4e-43 149.2 4.0 1.1 1 0 0 1 1 1 1 MED7 protein PAP2 PF01569.21 OAP65253.1 - 4.2e-28 97.8 1.0 4.2e-28 97.8 1.0 1.9 1 1 1 2 2 2 2 PAP2 superfamily DUF5510 PF17629.2 OAP65253.1 - 0.1 12.6 0.9 0.38 10.7 0.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5510) MNHE PF01899.16 OAP65253.1 - 0.13 12.0 3.1 12 5.6 3.7 2.7 1 1 1 2 2 2 0 Na+/H+ ion antiporter subunit RseC_MucC PF04246.12 OAP65253.1 - 0.14 12.1 0.6 19 5.2 0.3 2.5 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Sec62 PF03839.16 OAP65253.1 - 0.17 11.4 0.6 0.31 10.5 0.6 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 FMO-like PF00743.19 OAP65254.1 - 2.5e-18 65.8 0.0 1.6e-17 63.1 0.0 2.1 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OAP65254.1 - 2.1e-16 60.0 0.0 2.4e-13 50.0 0.1 2.9 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAP65254.1 - 8e-13 48.3 0.1 3e-12 46.4 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAP65254.1 - 2.6e-09 36.7 0.0 2.8e-06 26.7 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 OAP65254.1 - 2e-06 27.9 2.6 2.8e-06 27.5 0.2 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 OAP65254.1 - 5.6e-06 26.8 5.0 0.024 15.2 0.7 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 OAP65254.1 - 2.5e-05 23.7 1.3 0.0036 16.6 0.2 2.2 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 OAP65254.1 - 0.00011 22.0 1.8 0.00011 22.0 1.8 2.1 1 1 1 2 2 2 1 FAD dependent oxidoreductase Shikimate_DH PF01488.20 OAP65254.1 - 0.00039 20.5 0.0 1.2 9.2 0.0 2.6 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 OAP65254.1 - 0.00054 19.9 0.4 0.00085 19.3 0.4 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 OAP65254.1 - 0.0028 18.1 0.0 0.12 12.9 0.0 2.3 2 0 0 2 2 2 1 Putative NAD(P)-binding NAD_binding_9 PF13454.6 OAP65254.1 - 0.0063 16.5 1.7 0.056 13.4 0.1 2.8 3 0 0 3 3 3 1 FAD-NAD(P)-binding FAD_oxidored PF12831.7 OAP65254.1 - 0.0087 15.4 0.0 0.0087 15.4 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OAP65254.1 - 0.013 14.6 0.4 0.022 13.9 0.4 1.3 1 0 0 1 1 1 0 FAD binding domain Amino_oxidase PF01593.24 OAP65254.1 - 0.035 13.4 0.1 0.17 11.2 0.1 1.8 1 1 1 2 2 2 0 Flavin containing amine oxidoreductase HI0933_like PF03486.14 OAP65254.1 - 0.093 11.4 3.0 0.12 11.0 0.3 2.3 3 0 0 3 3 3 0 HI0933-like protein NAD_binding_2 PF03446.15 OAP65254.1 - 0.1 12.8 0.3 0.25 11.5 0.1 1.7 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase GIDA PF01134.22 OAP65254.1 - 7.3 5.6 8.6 0.074 12.1 1.0 1.5 2 0 0 2 2 2 0 Glucose inhibited division protein A DUF3439 PF11921.8 OAP65256.1 - 0.0041 17.1 9.2 0.0077 16.2 9.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) Mucin PF01456.17 OAP65256.1 - 0.019 15.0 14.2 0.019 15.0 14.2 1.5 2 0 0 2 2 2 0 Mucin-like glycoprotein Otopetrin PF03189.13 OAP65256.1 - 0.24 10.2 4.8 0.36 9.6 4.8 1.2 1 0 0 1 1 1 0 Otopetrin PI3K_1B_p101 PF10486.9 OAP65256.1 - 0.27 8.9 2.9 0.35 8.6 2.9 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Macoilin PF09726.9 OAP65256.1 - 1.3 7.5 10.8 1.6 7.2 10.8 1.1 1 0 0 1 1 1 0 Macoilin family SSP160 PF06933.11 OAP65256.1 - 1.9 6.6 17.0 3.2 5.8 17.0 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 NST1 PF13945.6 OAP65256.1 - 2 8.5 14.8 2.9 8.0 14.8 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator Zip PF02535.22 OAP65256.1 - 3 7.0 9.7 4 6.6 9.7 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 OAP65256.1 - 3.3 6.4 4.5 4.1 6.1 4.5 1.1 1 0 0 1 1 1 0 Presenilin MGC-24 PF05283.11 OAP65256.1 - 3.4 8.1 12.9 8.2 6.9 12.9 1.6 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Menin PF05053.13 OAP65256.1 - 3.6 5.8 7.3 4.8 5.4 7.3 1.1 1 0 0 1 1 1 0 Menin FAM76 PF16046.5 OAP65256.1 - 7.8 5.8 8.4 10 5.4 8.4 1.1 1 0 0 1 1 1 0 FAM76 protein MBOAT_2 PF13813.6 OAP65258.1 - 3.8e-09 36.7 1.2 8.7e-09 35.5 1.2 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family adh_short PF00106.25 OAP65259.1 - 6.8e-28 97.5 0.0 9.2e-28 97.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP65259.1 - 1.1e-21 77.5 0.0 3.4e-21 75.9 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP65259.1 - 7.3e-06 26.0 0.2 1.5e-05 25.0 0.0 1.5 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 OAP65259.1 - 0.073 12.2 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Shikimate_DH PF01488.20 OAP65259.1 - 0.13 12.3 0.0 0.32 11.0 0.0 1.7 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase SUR7 PF06687.12 OAP65260.1 - 6.2e-15 55.4 3.4 8.4e-15 55.0 3.4 1.1 1 0 0 1 1 1 1 SUR7/PalI family MIG-14_Wnt-bd PF06664.12 OAP65260.1 - 1.1 8.4 4.3 0.24 10.6 0.9 1.7 2 1 0 2 2 2 0 Wnt-binding factor required for Wnt secretion Abhydrolase_1 PF00561.20 OAP65261.1 - 5.1e-29 101.7 0.2 9.5e-29 100.8 0.2 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAP65261.1 - 1.2e-25 90.2 0.1 1.4e-16 60.5 0.1 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OAP65261.1 - 4.8e-21 76.4 0.6 5.6e-21 76.2 0.6 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 OAP65261.1 - 1.2e-08 34.7 0.1 0.0012 18.4 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 OAP65261.1 - 0.00012 22.0 0.0 0.0004 20.2 0.0 1.8 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Ndr PF03096.14 OAP65261.1 - 0.00018 20.3 0.0 0.085 11.6 0.0 2.1 2 0 0 2 2 2 2 Ndr family Abhydrolase_5 PF12695.7 OAP65261.1 - 0.00037 20.3 0.0 0.42 10.4 0.0 2.4 3 0 0 3 3 3 2 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 OAP65261.1 - 0.0012 18.5 0.0 0.38 10.3 0.0 2.2 2 0 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.18 OAP65261.1 - 0.0023 17.5 0.0 0.012 15.2 0.0 2.0 2 1 0 2 2 2 1 Dienelactone hydrolase family FSH1 PF03959.13 OAP65261.1 - 0.011 15.4 0.1 0.02 14.5 0.0 1.5 1 1 0 1 1 1 0 Serine hydrolase (FSH1) DUF915 PF06028.11 OAP65261.1 - 0.012 15.0 0.1 0.047 13.0 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Ser_hydrolase PF06821.13 OAP65261.1 - 0.014 15.3 0.0 0.17 11.7 0.0 2.1 2 0 0 2 2 2 0 Serine hydrolase MTD PF01993.18 OAP65261.1 - 0.016 14.5 0.0 0.029 13.7 0.0 1.3 1 0 0 1 1 1 0 methylene-5,6,7,8-tetrahydromethanopterin dehydrogenase AXE1 PF05448.12 OAP65261.1 - 0.018 13.7 0.2 0.36 9.4 0.0 2.6 2 1 1 3 3 3 0 Acetyl xylan esterase (AXE1) Acyl_transf_2 PF02273.15 OAP65261.1 - 0.051 12.8 0.0 0.24 10.6 0.0 1.8 2 0 0 2 2 2 0 Acyl transferase DUF1749 PF08538.10 OAP65261.1 - 0.064 12.3 0.1 0.12 11.4 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1749) Chlorophyllase2 PF12740.7 OAP65261.1 - 0.09 11.7 0.0 0.26 10.2 0.0 1.6 1 1 0 1 1 1 0 Chlorophyllase enzyme PAF-AH_p_II PF03403.13 OAP65261.1 - 0.18 10.3 0.0 13 4.2 0.0 2.1 1 1 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II BAAT_C PF08840.11 OAP65261.1 - 0.2 11.5 0.0 0.47 10.3 0.0 1.6 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_1 PF00561.20 OAP65262.1 - 1.5e-16 60.8 0.0 4.8e-16 59.2 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.18 OAP65262.1 - 4.2e-13 49.4 0.0 8.9e-11 41.7 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family Hydrolase_4 PF12146.8 OAP65262.1 - 9.7e-12 44.7 0.0 7.8e-11 41.7 0.0 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OAP65262.1 - 6.4e-11 43.3 0.1 9.2e-11 42.8 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 OAP65262.1 - 4.6e-07 29.5 0.0 4.8e-06 26.2 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family BAAT_C PF08840.11 OAP65262.1 - 1.1e-06 28.8 0.0 8.6e-06 25.8 0.0 2.0 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal FSH1 PF03959.13 OAP65262.1 - 3.7e-05 23.5 0.1 0.00036 20.3 0.1 2.1 1 1 0 1 1 1 1 Serine hydrolase (FSH1) PGAP1 PF07819.13 OAP65262.1 - 0.00062 19.6 0.0 0.00085 19.1 0.0 1.4 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_3 PF07859.13 OAP65262.1 - 0.0022 17.9 0.0 0.15 11.9 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 OAP65262.1 - 0.0038 17.1 0.2 1.1 9.0 0.0 2.3 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Peptidase_S15 PF02129.18 OAP65262.1 - 0.0071 16.0 0.0 0.063 12.9 0.0 2.1 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.20 OAP65262.1 - 0.0085 15.8 0.0 0.01 15.5 0.0 1.3 1 1 0 1 1 1 1 Putative esterase UPF0227 PF05728.12 OAP65262.1 - 0.02 14.9 0.0 0.036 14.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Abhydrolase_4 PF08386.10 OAP65262.1 - 0.11 12.6 0.0 0.33 11.1 0.0 1.8 1 1 0 1 1 1 0 TAP-like protein DUF915 PF06028.11 OAP65262.1 - 0.18 11.1 0.0 0.32 10.3 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Aminotran_1_2 PF00155.21 OAP65263.1 - 4.9e-34 118.1 0.0 6.7e-34 117.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II RPN7 PF10602.9 OAP65264.1 - 4.2e-57 192.6 0.4 7.1e-57 191.9 0.4 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 OAP65264.1 - 9.4e-15 55.0 0.0 2e-14 53.9 0.0 1.6 1 0 0 1 1 1 1 PCI domain DUF3091 PF11291.8 OAP65264.1 - 0.18 12.0 0.3 0.45 10.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3091) zf-RING_UBOX PF13445.6 OAP65265.1 - 0.0019 18.2 1.4 0.0058 16.6 1.4 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 OAP65265.1 - 0.0042 17.0 5.8 0.012 15.6 5.8 1.8 1 1 0 1 1 1 1 zinc-RING finger domain DUF3281 PF11685.8 OAP65265.1 - 0.0068 15.8 0.1 0.011 15.2 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3281) zf-C3HC4_2 PF13923.6 OAP65265.1 - 1.2 9.1 5.5 0.16 11.8 0.7 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAP65265.1 - 2.8 8.3 11.9 1.4 9.4 7.5 2.5 1 1 1 2 2 2 0 Ring finger domain Prok-RING_4 PF14447.6 OAP65265.1 - 7.4 6.5 8.3 0.35 10.8 2.4 1.8 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 U-box PF04564.15 OAP65266.1 - 1.4e-14 54.0 0.0 2.7e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 U-box domain VWA PF00092.28 OAP65267.1 - 2.5e-05 24.6 0.0 3.6e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF1194 PF06707.11 OAP65267.1 - 0.021 14.0 0.0 0.028 13.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1194) VWA_3 PF13768.6 OAP65267.1 - 0.14 12.0 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 von Willebrand factor type A domain Sugar_tr PF00083.24 OAP65268.1 - 2.3e-39 135.6 27.2 1.3e-24 86.9 7.4 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 OAP65268.1 - 3.4e-22 78.8 34.2 2e-13 50.0 22.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily AMP-binding PF00501.28 OAP65269.1 - 4.6e-98 328.6 0.0 5.4e-98 328.3 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAP65269.1 - 2.2e-14 54.2 0.1 5.1e-14 53.0 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PEX11 PF05648.14 OAP65270.1 - 2.7e-66 223.3 0.4 3e-66 223.1 0.4 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) PEPCK_ATP PF01293.20 OAP65271.1 - 7.4e-218 723.9 0.0 8.7e-218 723.6 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_16 PF13191.6 OAP65271.1 - 0.055 13.9 0.0 0.1 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain HCMVantigenic_N PF12154.8 OAP65271.1 - 0.073 13.2 0.9 0.19 11.8 0.9 1.8 1 0 0 1 1 1 0 Glycoprotein B N-terminal antigenic domain of HCMV AAA_33 PF13671.6 OAP65271.1 - 0.16 12.1 0.0 0.32 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Metallophos PF00149.28 OAP65273.1 - 3.7e-12 47.2 3.1 8.3e-12 46.0 3.1 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OAP65273.1 - 3.3e-10 40.4 0.0 9.1e-08 32.5 0.0 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain Cupin_2 PF07883.11 OAP65274.1 - 1.4e-10 40.7 0.4 2.3e-10 40.0 0.4 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.7 OAP65274.1 - 0.00011 22.0 0.2 0.00015 21.5 0.2 1.2 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.19 OAP65274.1 - 0.0017 18.3 0.5 0.0023 17.8 0.5 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_3 PF05899.12 OAP65274.1 - 0.0033 17.1 0.2 0.0065 16.1 0.2 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF861) ABM PF03992.16 OAP65275.1 - 0.0036 17.4 0.0 0.0047 17.0 0.0 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase GMC_oxred_N PF00732.19 OAP65277.1 - 5.9e-61 206.4 0.0 7.4e-61 206.1 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAP65277.1 - 1.4e-30 106.8 0.0 2e-30 106.2 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 OAP65277.1 - 5e-06 25.8 0.1 8.7e-06 25.0 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 OAP65277.1 - 0.0013 18.9 0.4 0.0029 17.8 0.4 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 OAP65277.1 - 0.0066 15.2 0.0 0.012 14.4 0.0 1.4 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.24 OAP65277.1 - 0.0088 15.7 0.1 0.025 14.2 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase ApbA PF02558.16 OAP65277.1 - 0.1 12.2 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.27 OAP65277.1 - 0.12 12.9 1.2 3.8 8.2 0.0 2.9 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAP65277.1 - 0.15 11.3 0.0 0.47 9.6 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF1989 PF09347.10 OAP65278.1 - 5.2e-40 136.8 0.0 6.4e-40 136.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) Zn_clus PF00172.18 OAP65279.1 - 8.7e-08 32.2 9.9 1.6e-07 31.3 9.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2039 PF10217.9 OAP65279.1 - 0.31 11.4 6.6 0.69 10.3 6.6 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) HEAT_EZ PF13513.6 OAP65280.1 - 4.8e-20 71.7 7.2 0.00019 21.8 0.2 9.4 9 2 2 11 11 11 4 HEAT-like repeat HEAT PF02985.22 OAP65280.1 - 1.4e-18 65.3 7.2 0.0074 16.5 0.0 9.5 10 0 0 10 10 9 3 HEAT repeat HEAT_2 PF13646.6 OAP65280.1 - 3e-17 62.8 3.5 0.00045 20.6 0.1 7.3 6 1 2 8 8 8 3 HEAT repeats IBN_N PF03810.19 OAP65280.1 - 3.9e-09 36.3 2.0 3.9e-09 36.3 2.0 3.3 3 0 0 3 3 3 1 Importin-beta N-terminal domain IFRD PF05004.13 OAP65280.1 - 1.6e-08 34.0 6.8 0.039 13.1 2.4 4.9 2 1 2 4 4 4 3 Interferon-related developmental regulator (IFRD) Vac14_Fab1_bd PF12755.7 OAP65280.1 - 7e-07 29.8 0.1 8.6 7.0 0.0 6.9 7 1 1 8 8 6 1 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 OAP65280.1 - 1.3e-06 28.2 0.2 0.12 11.9 0.0 4.4 4 1 1 5 5 5 2 CLASP N terminal Cnd1 PF12717.7 OAP65280.1 - 1.8e-05 24.8 5.4 0.12 12.4 0.0 5.5 7 1 1 8 8 7 1 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 OAP65280.1 - 3.6e-05 23.9 0.2 4.4 7.5 0.0 5.2 5 0 0 5 5 5 1 Required for nuclear transport of RNA pol II C-terminus 1 RIX1 PF08167.12 OAP65280.1 - 0.0014 18.4 0.0 6.8 6.4 0.0 4.6 4 2 1 5 5 5 1 rRNA processing/ribosome biogenesis Arm PF00514.23 OAP65280.1 - 0.0026 17.7 5.4 0.76 9.9 0.0 5.6 7 0 0 7 7 6 1 Armadillo/beta-catenin-like repeat MMS19_C PF12460.8 OAP65280.1 - 0.003 16.7 9.1 0.036 13.2 0.5 4.4 5 0 0 5 5 5 1 RNAPII transcription regulator C-terminal API5 PF05918.11 OAP65280.1 - 0.0035 16.2 1.4 0.1 11.4 0.0 2.7 2 0 0 2 2 2 1 Apoptosis inhibitory protein 5 (API5) UNC45-central PF11701.8 OAP65280.1 - 0.013 15.5 1.5 0.22 11.4 0.4 3.6 4 1 1 5 5 5 0 Myosin-binding striated muscle assembly central Cohesin_HEAT PF12765.7 OAP65280.1 - 0.02 15.2 0.1 3 8.2 0.0 4.1 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion DUF4042 PF13251.6 OAP65280.1 - 0.19 11.4 1.6 13 5.4 0.1 4.1 4 1 0 4 4 4 0 Domain of unknown function (DUF4042) SLAC1 PF03595.17 OAP65281.1 - 1.3e-85 287.6 57.2 1.6e-85 287.2 57.2 1.1 1 0 0 1 1 1 1 Voltage-dependent anion channel Sec15 PF04091.12 OAP65282.1 - 0.0038 16.7 0.1 0.13 11.6 0.0 2.1 2 0 0 2 2 2 2 Exocyst complex subunit Sec15-like Na_Ca_ex PF01699.24 OAP65283.1 - 2.7e-38 131.3 35.5 5.1e-21 75.2 14.8 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein LSM PF01423.22 OAP65284.1 - 1.9e-16 59.5 0.0 3.9e-16 58.5 0.0 1.6 1 0 0 1 1 1 1 LSM domain Methyltransf_25 PF13649.6 OAP65284.1 - 2.2e-11 44.3 0.0 5.6e-11 43.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAP65284.1 - 3.2e-11 43.7 0.0 2.5e-10 40.8 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAP65284.1 - 9.3e-08 32.7 0.0 2.6e-07 31.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAP65284.1 - 4.8e-07 29.7 0.0 7.8e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAP65284.1 - 6.9e-06 26.0 0.0 1.1e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain SM-ATX PF14438.6 OAP65284.1 - 0.00014 21.9 0.1 0.00033 20.7 0.1 1.5 1 0 0 1 1 1 1 Ataxin 2 SM domain Inhibitor_I24 PF10465.9 OAP65284.1 - 0.18 11.8 0.0 0.42 10.6 0.0 1.5 1 0 0 1 1 1 0 PinA peptidase inhibitor rRNA_methylase PF06962.12 OAP65284.1 - 0.21 11.5 0.0 0.46 10.5 0.0 1.4 1 0 0 1 1 1 0 Putative rRNA methylase Cys_Met_Meta_PP PF01053.20 OAP65285.1 - 3.1e-24 85.2 0.0 8.3e-24 83.8 0.0 1.6 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 OAP65285.1 - 0.00011 21.6 0.0 0.00019 20.8 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Rnk_N PF14760.6 OAP65285.1 - 0.99 9.9 5.1 21 5.7 0.3 3.3 3 0 0 3 3 3 0 Rnk N-terminus Dopey_N PF04118.14 OAP65287.1 - 1.6e-106 355.9 0.0 3.3e-106 354.9 0.0 1.5 1 0 0 1 1 1 1 Dopey, N-terminal ATP13 PF12921.7 OAP65287.1 - 0.084 12.7 0.0 0.33 10.8 0.0 2.0 1 0 0 1 1 1 0 Mitochondrial ATPase expression Mon1 PF03164.14 OAP65288.1 - 6.6e-150 499.7 0.0 7.7e-150 499.5 0.0 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 Pyridoxal_deC PF00282.19 OAP65289.1 - 4e-28 98.2 0.0 3.8e-27 95.0 0.0 2.1 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain SepSecS PF05889.13 OAP65289.1 - 0.055 12.1 0.0 0.096 11.4 0.0 1.3 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS zf-CCCH_2 PF14608.6 OAP65290.1 - 2.2e-13 50.1 61.1 1.9e-05 24.9 8.7 5.4 5 0 0 5 5 5 5 RNA-binding, Nab2-type zinc finger Nab2 PF11517.8 OAP65290.1 - 0.00066 19.9 0.0 0.0012 19.2 0.0 1.3 1 0 0 1 1 1 1 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) TctA PF01970.16 OAP65290.1 - 0.48 9.1 2.0 0.71 8.5 2.0 1.1 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctA family Pinin_SDK_N PF04697.13 OAP65290.1 - 1.5 9.5 9.1 1.3 9.6 3.1 2.5 2 0 0 2 2 2 0 pinin/SDK conserved region Glyco_hydro_20 PF00728.22 OAP65291.1 - 1.6e-63 215.3 0.0 2.3e-63 214.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain p450 PF00067.22 OAP65291.1 - 3.3e-61 207.5 0.0 4.4e-61 207.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 KH_1 PF00013.29 OAP65292.1 - 7.7e-92 301.1 30.4 1.2e-14 53.8 0.3 12.9 13 0 0 13 13 13 9 KH domain KH_2 PF07650.17 OAP65292.1 - 2e-13 50.0 21.5 0.037 13.9 0.2 7.7 5 2 2 7 7 7 5 KH domain KH_4 PF13083.6 OAP65292.1 - 5.2e-09 35.8 4.2 0.22 11.4 0.0 6.2 6 0 0 6 6 6 2 KH domain SLS PF14611.6 OAP65292.1 - 7e-09 35.8 8.1 0.047 13.5 0.1 6.2 3 2 5 8 8 8 3 Mitochondrial inner-membrane-bound regulator KH_5 PF13184.6 OAP65292.1 - 0.0048 17.0 12.7 14 5.8 0.1 6.9 7 0 0 7 7 7 2 NusA-like KH domain DUF1664 PF07889.12 OAP65292.1 - 0.041 13.9 4.3 3.1 7.8 0.6 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF4349 PF14257.6 OAP65292.1 - 0.63 9.4 4.3 2.9 7.3 0.3 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF4349) FAD_binding_1 PF00667.20 OAP65293.1 - 1.6e-61 207.7 0.0 2.7e-61 207.0 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 OAP65293.1 - 1.3e-10 41.8 0.0 4.7e-10 40.1 0.0 1.9 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain POR PF01558.18 OAP65293.1 - 1.2e-09 38.5 0.1 3.5e-09 37.0 0.1 1.8 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase PFOR_II PF17147.4 OAP65293.1 - 1.3e-06 28.6 0.1 3.3e-06 27.3 0.1 1.7 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II Transketolase_C PF02780.20 OAP65293.1 - 0.00019 21.3 0.0 0.0007 19.5 0.0 2.0 1 0 0 1 1 1 1 Transketolase, C-terminal domain NAD_binding_10 PF13460.6 OAP65294.1 - 3.5e-07 30.3 0.0 5.2e-07 29.7 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 OAP65294.1 - 0.00033 20.3 0.1 0.00086 18.9 0.1 1.9 1 1 0 1 1 1 1 NmrA-like family HIM1 PF08732.10 OAP65294.1 - 0.0004 19.9 0.0 0.0006 19.4 0.0 1.3 1 0 0 1 1 1 1 HIM1 Epimerase PF01370.21 OAP65294.1 - 0.00058 19.4 0.0 0.0025 17.3 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1471 PF07338.13 OAP65294.1 - 0.0045 16.9 0.1 0.01 15.8 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1471) SDH_alpha PF03313.15 OAP65296.1 - 1.2e-99 333.2 0.3 1.5e-99 332.9 0.3 1.1 1 0 0 1 1 1 1 Serine dehydratase alpha chain SDH_beta PF03315.15 OAP65296.1 - 3.3e-54 183.5 0.0 7.7e-54 182.3 0.0 1.6 1 0 0 1 1 1 1 Serine dehydratase beta chain MFS_1 PF07690.16 OAP65297.1 - 5.8e-30 104.4 31.5 2.4e-29 102.4 31.7 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 OAP65297.1 - 1.7e-06 27.6 17.4 5.9e-05 22.5 5.2 2.7 2 1 1 3 3 3 2 Uncharacterised MFS-type transporter YbfB Aldedh PF00171.22 OAP65298.1 - 1.2e-139 465.8 0.0 1.4e-139 465.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 OAP65298.1 - 0.12 11.8 0.0 0.91 8.9 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) adh_short PF00106.25 OAP65299.1 - 1.2e-18 67.3 0.2 4.3e-15 55.7 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAP65299.1 - 1.3e-09 38.0 0.1 2.9e-07 30.3 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP65299.1 - 1.8e-06 28.0 0.1 3.2e-06 27.2 0.1 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OAP65299.1 - 0.019 14.1 0.0 0.033 13.3 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 OAP65299.1 - 0.043 14.1 0.0 0.091 13.0 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 OAP65299.1 - 0.048 13.7 0.1 0.089 12.9 0.1 1.5 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.6 OAP65299.1 - 0.083 12.8 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding GST_N_2 PF13409.6 OAP65300.1 - 5.5e-24 84.2 0.1 1.4e-23 83.0 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAP65300.1 - 3.2e-13 49.5 0.0 7.7e-13 48.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 OAP65300.1 - 2.2e-05 24.8 0.1 0.0012 19.2 0.1 2.3 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_5 PF16865.5 OAP65300.1 - 0.0002 21.9 0.0 0.00038 21.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OAP65300.1 - 0.0014 18.8 0.0 0.0036 17.5 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OAP65300.1 - 0.0051 17.0 0.0 0.011 15.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MBOAT PF03062.19 OAP65301.1 - 7.5e-47 160.4 15.2 1.1e-46 159.8 15.2 1.3 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family T4SS_CagC PF16943.5 OAP65301.1 - 0.035 14.3 0.2 0.081 13.1 0.2 1.5 1 0 0 1 1 1 0 Cag pathogenicity island, type IV secretory system zf-HIT PF04438.16 OAP65302.1 - 0.00093 19.0 4.6 0.0017 18.2 4.6 1.4 1 0 0 1 1 1 1 HIT zinc finger WLM PF08325.10 OAP65303.1 - 5.3e-27 95.1 0.1 1.2e-26 94.0 0.1 1.7 1 1 0 1 1 1 1 WLM domain DUF45 PF01863.17 OAP65303.1 - 8.2e-07 29.3 1.3 1.9e-06 28.1 1.3 1.5 1 0 0 1 1 1 1 Protein of unknown function DUF45 Zn_ribbon_17 PF17120.5 OAP65303.1 - 0.22 11.2 2.4 0.48 10.1 2.4 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_10 PF16685.5 OAP65303.1 - 0.33 11.1 2.3 0.68 10.1 2.3 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 Ndc1_Nup PF09531.10 OAP65303.1 - 1.8 7.1 4.9 2.7 6.6 4.9 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DZR PF12773.7 OAP65303.1 - 2.4 8.3 5.4 13 5.9 5.4 2.1 1 1 0 1 1 1 0 Double zinc ribbon CAP59_mtransfer PF11735.8 OAP65304.1 - 4.2e-69 232.9 0.0 5.4e-69 232.5 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Acyl-CoA_dh_1 PF00441.24 OAP65305.1 - 1.9e-12 47.6 0.6 1.1e-10 41.9 0.6 2.5 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 OAP65305.1 - 8.8e-11 41.9 0.1 3.2e-10 40.0 0.1 2.0 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain AidB_N PF18158.1 OAP65305.1 - 2.5e-10 40.5 0.0 5.7e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 Adaptive response protein AidB N-terminal domain GTP_EFTU PF00009.27 OAP65306.1 - 6.2e-09 35.7 0.0 1.6e-08 34.3 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OAP65306.1 - 0.036 14.2 0.0 0.1 12.7 0.0 1.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OAP65306.1 - 0.056 13.3 0.2 8.6 6.2 0.1 2.5 2 0 0 2 2 2 0 RsgA GTPase DUF1180 PF06679.12 OAP65306.1 - 0.16 12.4 1.0 0.32 11.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Pkr1 PF08636.10 OAP65307.1 - 2.3e-31 107.8 4.5 3e-31 107.4 4.5 1.1 1 0 0 1 1 1 1 ER protein Pkr1 MSA-2c PF12238.8 OAP65307.1 - 0.0026 17.8 5.6 0.004 17.2 5.6 1.3 1 0 0 1 1 1 1 Merozoite surface antigen 2c Kei1 PF08552.11 OAP65307.1 - 0.051 13.5 0.9 0.086 12.7 0.9 1.4 1 1 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 FHIPEP PF00771.20 OAP65307.1 - 0.1 11.0 0.0 0.13 10.7 0.0 1.1 1 0 0 1 1 1 0 FHIPEP family OAD_gamma PF04277.13 OAP65307.1 - 0.48 11.1 4.9 2.1 9.0 4.9 2.3 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain zf-C2H2 PF00096.26 OAP65308.1 - 0.00015 22.0 4.2 0.3 11.6 0.5 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAP65308.1 - 0.0016 19.1 2.7 0.74 10.8 0.2 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger Zn_ribbon_SprT PF17283.2 OAP65308.1 - 0.07 13.1 0.6 0.19 11.7 0.6 1.7 1 0 0 1 1 1 0 SprT-like zinc ribbon domain UPF0547 PF10571.9 OAP65308.1 - 0.076 13.1 0.2 0.14 12.2 0.2 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 F-box-like PF12937.7 OAP65309.1 - 0.0014 18.5 1.8 0.0017 18.2 0.2 2.0 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.7 OAP65310.1 - 1.4e-05 24.8 0.0 2.9e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAP65310.1 - 0.0005 19.9 0.3 0.0032 17.3 0.5 2.3 2 0 0 2 2 2 1 F-box domain F-box_4 PF15966.5 OAP65310.1 - 0.011 15.6 0.1 0.018 14.9 0.1 1.4 1 0 0 1 1 1 0 F-box Complex1_LYR_2 PF13233.6 OAP65311.1 - 9.4e-19 68.0 0.2 1.4e-18 67.4 0.2 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 OAP65311.1 - 2e-09 37.4 0.1 3.2e-09 36.7 0.1 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Adeno_terminal PF02459.15 OAP65311.1 - 0.11 10.9 0.2 0.13 10.6 0.2 1.0 1 0 0 1 1 1 0 Adenoviral DNA terminal protein Erythro_esteras PF05139.14 OAP65312.1 - 8.8e-118 394.0 6.3 1e-117 393.8 6.3 1.1 1 0 0 1 1 1 1 Erythromycin esterase HET PF06985.11 OAP65313.1 - 2.3e-15 57.2 2.2 2.3e-15 57.2 2.2 2.1 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) CAP_N PF01213.19 OAP65313.1 - 5 6.5 7.8 10 5.5 7.8 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.11 OAP65313.1 - 9.6 6.2 9.6 0.32 11.1 3.0 1.8 2 0 0 2 2 2 0 Mitochondrial fission regulator Myb_DNA-binding PF00249.31 OAP65314.1 - 2e-18 66.3 6.7 1.4e-08 34.7 2.0 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OAP65314.1 - 4.1e-12 46.2 6.0 5.9e-09 36.1 0.6 2.9 1 1 1 2 2 2 2 Myb-like DNA-binding domain zf-C2H2_4 PF13894.6 OAP65314.1 - 2.5e-07 31.0 14.8 0.012 16.4 0.6 4.9 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2 PF00096.26 OAP65314.1 - 1.8e-06 28.0 16.5 0.03 14.8 0.7 4.6 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 OAP65314.1 - 0.012 15.8 0.1 0.012 15.8 0.1 3.6 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 OAP65314.1 - 0.037 13.8 7.2 0.32 10.8 0.1 3.2 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-C2H2_2 PF12756.7 OAP65314.1 - 0.049 14.0 11.8 0.19 12.1 1.1 3.3 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Elf1 PF05129.13 OAP65314.1 - 0.14 12.2 4.4 4.6 7.4 0.4 2.7 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like LIM PF00412.22 OAP65314.1 - 0.29 11.4 11.1 0.77 10.0 1.5 2.5 2 0 0 2 2 2 0 LIM domain zf-C2H2_6 PF13912.6 OAP65314.1 - 0.88 9.6 8.6 6.9 6.8 0.3 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2HC_2 PF13913.6 OAP65314.1 - 1.2 9.2 6.1 13 5.8 0.3 3.2 4 0 0 4 4 4 0 zinc-finger of a C2HC-type zf-met PF12874.7 OAP65314.1 - 2 8.9 17.1 0.47 10.9 0.1 4.0 5 0 0 5 5 4 0 Zinc-finger of C2H2 type zf-BED PF02892.15 OAP65314.1 - 2.2 8.4 4.3 5.5 7.1 0.5 2.5 2 0 0 2 2 2 0 BED zinc finger zinc_ribbon_15 PF17032.5 OAP65314.1 - 5 7.9 6.9 12 6.7 0.5 2.7 3 0 0 3 3 2 0 zinc-ribbon family Vma12 PF11712.8 OAP65315.1 - 1e-40 139.0 0.0 1.3e-40 138.7 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase ATP-synt_I PF03899.15 OAP65315.1 - 0.0074 16.6 0.2 0.013 15.8 0.2 1.3 1 0 0 1 1 1 1 ATP synthase I chain TT_ORF2 PF02957.15 OAP65315.1 - 0.17 12.8 0.0 0.42 11.5 0.0 1.5 2 0 0 2 2 2 0 TT viral ORF2 Amidohydro_1 PF01979.20 OAP65316.1 - 1.4e-28 100.2 0.0 6.1e-27 94.8 0.0 2.2 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 OAP65316.1 - 7.1e-11 42.2 0.1 5.8e-06 26.0 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_2 PF04909.14 OAP65316.1 - 0.039 13.7 0.1 0.079 12.7 0.1 1.5 1 1 0 1 1 1 0 Amidohydrolase GFA PF04828.14 OAP65317.1 - 3.5e-21 75.3 0.1 4.6e-21 75.0 0.1 1.1 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Auto_anti-p27 PF06677.12 OAP65317.1 - 0.025 14.8 2.7 0.12 12.6 0.0 2.4 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) ADK_lid PF05191.14 OAP65317.1 - 0.092 12.8 0.0 0.092 12.8 0.0 1.8 2 0 0 2 2 2 0 Adenylate kinase, active site lid K_oxygenase PF13434.6 OAP65318.1 - 1.1e-15 57.6 0.0 1.6e-13 50.5 0.0 2.3 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 OAP65318.1 - 3.8e-14 52.7 0.0 1.1e-13 51.2 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAP65318.1 - 9.9e-13 48.0 0.0 8.1e-10 38.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 OAP65318.1 - 4e-12 45.3 0.0 3e-11 42.5 0.0 1.9 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Thi4 PF01946.17 OAP65318.1 - 2.8e-05 23.5 0.1 0.00084 18.6 0.0 2.2 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 OAP65318.1 - 0.00021 21.4 0.0 0.0007 19.8 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 OAP65318.1 - 0.0003 20.8 0.6 0.94 9.4 0.1 3.4 2 1 0 2 2 2 2 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 OAP65318.1 - 0.007 15.5 0.0 0.082 11.9 0.1 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.24 OAP65318.1 - 0.061 12.9 0.6 15 5.0 0.0 3.1 3 0 0 3 3 3 0 FAD dependent oxidoreductase DUF4863 PF16155.5 OAP65319.1 - 2.2e-68 228.9 0.0 2.5e-68 228.7 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4863) p450 PF00067.22 OAP65320.1 - 9.6e-73 245.5 0.0 1.7e-72 244.7 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 SURF6 PF04935.12 OAP65321.1 - 2.9e-47 161.1 40.2 2.9e-47 161.1 40.2 3.8 2 1 1 3 3 3 1 Surfeit locus protein 6 RRP14 PF15459.6 OAP65321.1 - 2.6e-17 63.2 1.5 2.6e-17 63.2 1.5 7.7 6 3 1 7 7 7 1 60S ribosome biogenesis protein Rrp14 LysM PF01476.20 OAP65322.1 - 1.3e-10 41.2 1.5 1.5e-07 31.3 0.0 3.3 4 0 0 4 4 4 2 LysM domain TonB_C PF03544.14 OAP65322.1 - 0.0024 18.3 0.0 0.0057 17.1 0.0 1.6 1 0 0 1 1 1 1 Gram-negative bacterial TonB protein C-terminal Lysozyme_like PF13702.6 OAP65322.1 - 0.011 15.4 0.6 0.027 14.2 0.6 1.6 1 1 0 1 1 1 0 Lysozyme-like Sulfate_transp PF00916.20 OAP65323.1 - 1.2e-94 317.1 18.1 2.1e-94 316.4 18.1 1.3 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 OAP65323.1 - 2.4e-06 27.1 0.0 5e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 OAP65323.1 - 0.12 12.7 0.1 0.53 10.7 0.1 2.1 2 0 0 2 2 2 0 STAS domain Lactamase_B PF00753.27 OAP65324.1 - 1.2e-09 38.5 1.4 1.5e-07 31.6 1.4 2.3 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OAP65324.1 - 0.00091 18.8 0.0 0.0015 18.1 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 OAP65324.1 - 0.09 12.7 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Pyr_redox_2 PF07992.14 OAP65325.1 - 9.7e-12 44.7 0.0 5.7e-08 32.3 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAP65325.1 - 0.0061 16.6 0.0 0.035 14.1 0.0 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.24 OAP65325.1 - 0.0063 16.1 0.2 0.01 15.4 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 OAP65325.1 - 0.11 11.6 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Malic_M PF03949.15 OAP65325.1 - 0.16 11.2 0.1 3.3 6.9 0.1 2.2 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain FAD_binding_3 PF01494.19 OAP65325.1 - 0.17 11.1 0.0 0.33 10.1 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain MFS_1 PF07690.16 OAP65326.1 - 1e-32 113.5 35.9 1e-32 113.5 35.9 1.6 1 1 0 2 2 2 1 Major Facilitator Superfamily cNMP_binding PF00027.29 OAP65327.1 - 1.3e-39 134.2 0.0 5e-20 71.4 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.17 OAP65327.1 - 2.5e-07 30.3 0.0 4.4e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit AMPK1_CBM PF16561.5 OAP65328.1 - 9e-18 64.3 0.3 1.7e-17 63.4 0.3 1.3 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase CBM_48 PF02922.18 OAP65328.1 - 0.0006 20.1 0.5 0.0013 19.0 0.1 1.7 2 0 0 2 2 2 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) CBM53 PF16760.5 OAP65328.1 - 0.079 13.6 0.2 0.17 12.5 0.2 1.5 1 0 0 1 1 1 0 Starch/carbohydrate-binding module (family 53) Thioredoxin_6 PF13848.6 OAP65329.1 - 6.6e-25 88.1 0.1 7e-23 81.5 0.0 2.0 1 1 1 2 2 2 2 Thioredoxin-like domain Thioredoxin PF00085.20 OAP65329.1 - 0.034 14.1 0.0 0.27 11.2 0.0 2.1 2 1 0 2 2 2 0 Thioredoxin AfsA PF03756.13 OAP65329.1 - 0.12 12.4 0.5 11 6.1 0.1 2.7 3 0 0 3 3 3 0 A-factor biosynthesis hotdog domain 2OG-FeII_Oxy_3 PF13640.6 OAP65330.1 - 6.4e-09 36.6 0.0 1.3e-08 35.6 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily eRF1_1 PF03463.15 OAP65331.1 - 1.6e-48 163.9 0.0 2.6e-48 163.3 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.15 OAP65331.1 - 4.8e-20 72.2 0.0 7e-20 71.7 0.0 1.2 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 OAP65331.1 - 2.6e-18 66.6 0.0 4.5e-18 65.8 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 3 CCDC66 PF15236.6 OAP65332.1 - 0.16 11.8 16.2 0.35 10.7 16.2 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 66 DIX PF00778.17 OAP65332.1 - 0.16 11.8 0.1 2.3 8.1 0.0 2.2 2 0 0 2 2 2 0 DIX domain Ycf1 PF05758.12 OAP65332.1 - 1.8 6.4 6.3 2.3 6.0 6.3 1.1 1 0 0 1 1 1 0 Ycf1 MFS_1 PF07690.16 OAP65333.1 - 1.4e-39 136.1 34.9 1.4e-39 136.1 34.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAP65333.1 - 5.3e-13 48.6 9.4 5.3e-13 48.6 9.4 2.6 2 2 0 2 2 2 1 Sugar (and other) transporter GPR_Gpa2_C PF11970.8 OAP65333.1 - 0.59 10.3 2.9 9.7 6.4 0.6 3.1 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 C-term NPR2 PF06218.11 OAP65334.1 - 1.2e-124 416.5 0.0 9.1e-124 413.5 0.0 1.9 1 1 0 1 1 1 1 Nitrogen permease regulator 2 MFS_1 PF07690.16 OAP65335.1 - 3.1e-25 88.9 34.1 3.1e-25 88.9 34.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAP65335.1 - 0.00096 18.1 15.4 0.00096 18.1 15.4 3.1 2 1 0 3 3 3 1 Sugar (and other) transporter Gemini_C4 PF01492.17 OAP65335.1 - 0.096 12.6 0.1 0.19 11.7 0.1 1.4 1 0 0 1 1 1 0 Geminivirus C4 protein Amidase PF01425.21 OAP65336.1 - 5e-81 272.9 0.0 1.8e-80 271.1 0.0 1.7 1 1 0 1 1 1 1 Amidase SGL PF08450.12 OAP65337.1 - 1.3e-31 110.1 0.1 2.6e-31 109.1 0.1 1.5 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 OAP65337.1 - 2.2e-05 24.5 0.0 0.00012 22.2 0.0 2.1 2 0 0 2 2 2 1 Arylesterase Str_synth PF03088.16 OAP65337.1 - 0.00096 19.2 0.0 0.0061 16.6 0.0 2.3 3 0 0 3 3 3 1 Strictosidine synthase NHL PF01436.21 OAP65337.1 - 0.0012 18.8 2.4 0.078 13.1 0.0 3.2 3 0 0 3 3 3 1 NHL repeat Reg_prop PF07494.11 OAP65337.1 - 0.12 12.7 0.5 6.7 7.3 0.1 3.2 2 0 0 2 2 2 0 Two component regulator propeller Rep_1B PF17873.1 OAP65337.1 - 0.15 12.0 1.5 3.3 7.6 0.8 2.7 2 0 0 2 2 2 0 Replicase polyprotein 1ab PALP PF00291.25 OAP65338.1 - 9.4e-64 215.6 0.0 1.5e-63 215.0 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme IlvN PF07991.12 OAP65339.1 - 7.9e-47 158.9 0.0 1.2e-46 158.3 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 OAP65339.1 - 1.2e-39 135.9 0.0 1.8e-39 135.3 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.17 OAP65339.1 - 0.038 14.6 0.0 0.1 13.2 0.0 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Patatin PF01734.22 OAP65340.1 - 3e-25 89.6 0.3 6.6e-25 88.5 0.3 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase MMR_HSR1 PF01926.23 OAP65340.1 - 0.00021 21.4 0.0 0.00083 19.4 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 OAP65340.1 - 0.0014 19.2 0.0 0.0043 17.6 0.0 1.8 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 OAP65340.1 - 0.0055 16.6 0.1 0.014 15.3 0.1 1.6 1 0 0 1 1 1 1 RsgA GTPase ABC2_membrane PF01061.24 OAP65341.1 - 6.7e-90 300.1 48.8 6.7e-47 159.6 19.6 2.5 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 OAP65341.1 - 3.2e-40 137.8 0.0 1.3e-17 64.6 0.0 3.8 4 0 0 4 4 3 3 ABC transporter PDR_CDR PF06422.12 OAP65341.1 - 4.7e-34 116.1 11.6 1.2e-32 111.6 0.0 3.8 4 0 0 4 4 3 2 CDR ABC transporter ABC_trans_N PF14510.6 OAP65341.1 - 7.3e-18 65.0 0.2 2.4e-17 63.3 0.2 1.9 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_33 PF13671.6 OAP65341.1 - 2.6e-07 30.9 0.0 0.014 15.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 OAP65341.1 - 7.2e-06 26.5 0.1 0.014 15.8 0.1 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 OAP65341.1 - 8.3e-06 25.8 1.1 0.18 11.6 0.0 3.7 3 1 1 4 4 3 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 OAP65341.1 - 1.3e-05 24.5 41.0 0.00046 19.4 16.1 2.5 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_18 PF13238.6 OAP65341.1 - 2.9e-05 24.6 0.0 0.09 13.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 OAP65341.1 - 6.5e-05 22.9 0.1 0.0057 16.6 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 OAP65341.1 - 8.7e-05 22.2 1.9 0.0012 18.5 0.8 2.7 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.6 OAP65341.1 - 0.00019 21.1 1.3 0.014 15.1 0.2 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain SMC_N PF02463.19 OAP65341.1 - 0.0012 18.3 0.0 0.38 10.2 0.0 3.5 3 1 0 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 OAP65341.1 - 0.0018 18.5 0.0 1.4 9.2 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 OAP65341.1 - 0.0023 18.4 0.4 0.35 11.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 OAP65341.1 - 0.0051 16.6 0.4 0.32 10.7 0.1 2.5 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 OAP65341.1 - 0.0065 16.1 0.6 0.16 11.6 0.1 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 OAP65341.1 - 0.018 14.8 0.3 5.5 6.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 OAP65341.1 - 0.026 14.4 0.4 3.9 7.4 0.3 2.6 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.6 OAP65341.1 - 0.041 14.1 0.0 4.7 7.4 0.1 2.6 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 OAP65341.1 - 0.087 12.7 0.0 3.2 7.6 0.0 2.2 2 0 0 2 2 2 0 Rad17 P-loop domain IstB_IS21 PF01695.17 OAP65341.1 - 0.17 11.6 0.1 16 5.2 0.0 2.6 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA PF00004.29 OAP65341.1 - 0.2 12.1 0.0 32 5.0 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) BTB PF00651.31 OAP65342.1 - 7.2e-05 23.0 0.0 0.00017 21.8 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain NAD_binding_10 PF13460.6 OAP65343.1 - 5.5e-08 32.9 0.0 7.1e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAP65343.1 - 0.00054 19.5 0.0 0.00075 19.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 OAP65343.1 - 0.00075 18.7 0.0 0.0011 18.1 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein DapB_N PF01113.20 OAP65343.1 - 0.0015 18.7 0.3 0.0044 17.1 0.3 1.8 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Polysacc_synt_2 PF02719.15 OAP65343.1 - 0.0031 16.7 0.0 0.013 14.7 0.0 1.8 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 OAP65343.1 - 0.0094 15.0 0.0 0.012 14.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 OAP65343.1 - 0.023 14.6 0.0 0.034 14.1 0.0 1.3 1 0 0 1 1 1 0 KR domain NmrA PF05368.13 OAP65343.1 - 0.027 14.1 0.0 0.094 12.3 0.0 1.8 1 1 0 1 1 1 0 NmrA-like family RmlD_sub_bind PF04321.17 OAP65343.1 - 0.062 12.4 0.0 0.082 12.0 0.0 1.1 1 0 0 1 1 1 0 RmlD substrate binding domain Sacchrp_dh_NADP PF03435.18 OAP65343.1 - 0.1 12.9 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 OAP65343.1 - 0.12 12.8 0.1 0.2 12.1 0.1 1.5 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Chitin_synth_1 PF01644.17 OAP65344.1 - 9.6e-70 233.8 0.0 1.5e-69 233.1 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase UQ_con PF00179.26 OAP65344.1 - 2.7e-36 124.3 0.0 4.7e-36 123.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Chitin_synth_1N PF08407.11 OAP65344.1 - 2.1e-28 98.1 0.0 4.1e-28 97.1 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 OAP65344.1 - 3.6e-24 85.3 4.8 1.2e-18 67.0 0.0 2.5 3 0 0 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.6 OAP65344.1 - 3.7e-07 30.3 0.9 3.7e-07 30.3 0.9 2.2 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 OAP65344.1 - 0.093 12.6 0.0 1.1 9.1 0.0 2.5 2 0 0 2 2 2 0 Glycosyltransferase like family 2 Opy2 PF09463.10 OAP65345.1 - 2.2e-09 37.5 24.4 3.4e-09 36.9 24.4 1.3 1 0 0 1 1 1 1 Opy2 protein Syndecan PF01034.20 OAP65345.1 - 0.15 12.0 0.7 0.28 11.1 0.7 1.3 1 0 0 1 1 1 0 Syndecan domain DNA_primase_S PF01896.19 OAP65346.1 - 2.1e-58 197.3 0.1 3.8e-58 196.4 0.1 1.5 2 0 0 2 2 2 1 DNA primase small subunit Stealth_CR4 PF17103.5 OAP65346.1 - 0.14 12.1 0.7 0.92 9.4 0.4 2.4 2 0 0 2 2 2 0 Stealth protein CR4, conserved region 4 HHV6-IE PF03753.13 OAP65346.1 - 0.15 9.5 0.0 0.23 8.9 0.0 1.2 1 0 0 1 1 1 0 Human herpesvirus 6 immediate early protein Amidohydro_2 PF04909.14 OAP65347.1 - 2.3e-41 142.5 0.1 2.8e-41 142.2 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase Fungal_trans PF04082.18 OAP65348.1 - 7.5e-10 38.3 0.0 1.4e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP65348.1 - 0.021 15.0 4.3 0.035 14.2 4.3 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAP65349.1 - 9.4e-19 67.5 0.0 1.5e-18 66.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP65349.1 - 7.5e-10 38.8 7.7 1.2e-09 38.1 7.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short_C2 PF13561.6 OAP65350.1 - 1.2e-57 195.2 0.5 1.4e-57 194.9 0.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP65350.1 - 1.8e-42 145.0 0.3 2.3e-42 144.7 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAP65350.1 - 1.5e-11 44.5 0.2 2.5e-11 43.8 0.2 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAP65350.1 - 0.0081 15.6 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sugar_tr PF00083.24 OAP65351.1 - 9.6e-88 295.0 23.1 1.1e-87 294.8 23.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP65351.1 - 1.4e-11 44.0 72.6 2.1e-10 40.1 37.2 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily SLT PF01464.20 OAP65352.1 - 0.012 15.2 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 Transglycosylase SLT domain Lysozyme_like PF13702.6 OAP65352.1 - 0.03 14.0 1.9 0.038 13.7 0.2 2.1 2 1 0 2 2 2 0 Lysozyme-like Sugar_tr PF00083.24 OAP65353.1 - 7.7e-85 285.4 23.6 9.5e-85 285.1 23.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP65353.1 - 8.9e-19 67.6 30.2 4.5e-17 62.0 24.4 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Zn_clus PF00172.18 OAP65354.1 - 1.2e-08 34.9 9.6 2.2e-08 34.1 9.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAP65354.1 - 0.0016 17.5 0.5 0.078 12.0 0.3 2.5 2 1 0 2 2 2 1 Fungal specific transcription factor domain SnoaL PF07366.12 OAP65355.1 - 0.00081 19.2 0.0 0.0016 18.2 0.0 1.5 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 OAP65355.1 - 0.0023 18.5 0.0 0.0051 17.4 0.0 1.5 1 0 0 1 1 1 1 SnoaL-like domain DEAD PF00270.29 OAP65356.1 - 1.2e-44 152.2 0.0 2e-44 151.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAP65356.1 - 1.3e-23 83.4 0.0 5.5e-23 81.4 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 OAP65356.1 - 1.2e-19 70.3 0.1 2.2e-19 69.4 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 OAP65356.1 - 7e-05 22.9 0.5 0.00012 22.1 0.0 1.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 OAP65356.1 - 0.12 12.6 0.2 0.62 10.3 0.0 2.2 3 0 0 3 3 3 0 AAA domain TIMELESS_C PF05029.13 OAP65356.1 - 0.49 9.5 10.7 0.74 8.9 10.7 1.2 1 0 0 1 1 1 0 Timeless protein C terminal region DUF4551 PF15087.6 OAP65356.1 - 2.4 6.9 7.2 4.9 5.9 7.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Pro-kuma_activ PF09286.11 OAP65357.1 - 4.3e-33 114.6 0.0 8.6e-33 113.6 0.0 1.5 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Sarcoglycan_2 PF05510.13 OAP65357.1 - 0.18 10.6 0.1 0.29 9.8 0.1 1.2 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon Pkinase PF00069.25 OAP65358.1 - 6.2e-68 229.0 0.0 7.8e-68 228.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP65358.1 - 4.2e-32 111.4 0.0 5.9e-32 111.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OAP65358.1 - 0.005 15.8 0.0 0.02 13.9 0.0 2.0 2 1 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 OAP65358.1 - 0.035 13.4 0.0 0.068 12.5 0.0 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OAP65358.1 - 0.048 13.6 0.6 0.16 11.9 0.0 2.1 3 0 0 3 3 3 0 Phosphotransferase enzyme family OTU PF02338.19 OAP65359.1 - 9.4e-22 77.9 1.4 2.6e-21 76.4 0.0 2.3 3 0 0 3 3 3 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 OAP65359.1 - 0.0011 18.5 1.8 0.74 9.2 0.0 2.8 2 1 1 3 3 3 2 Peptidase C65 Otubain CEP19 PF14933.6 OAP65359.1 - 4.4 7.6 7.9 0.96 9.7 3.6 1.9 1 1 1 2 2 2 0 CEP19-like protein Rib_recp_KP_reg PF05104.12 OAP65359.1 - 5.9 7.9 18.2 12 6.9 18.2 1.5 1 0 0 1 1 1 0 Ribosome receptor lysine/proline rich region TPMT PF05724.11 OAP65360.1 - 8.8e-29 100.7 0.1 5.5e-28 98.1 0.1 2.1 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_25 PF13649.6 OAP65360.1 - 2.9e-05 24.7 0.0 0.00019 22.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAP65360.1 - 0.00028 21.5 0.0 0.0014 19.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAP65360.1 - 0.002 18.0 0.0 0.0027 17.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAP65360.1 - 0.0047 16.7 0.1 0.0092 15.8 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase domain N2227 PF07942.12 OAP65360.1 - 0.075 12.2 0.0 0.1 11.8 0.0 1.1 1 0 0 1 1 1 0 N2227-like protein TehB PF03848.14 OAP65360.1 - 0.096 12.1 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_12 PF08242.12 OAP65360.1 - 0.19 12.5 0.0 0.7 10.7 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Gln-synt_C-ter PF18318.1 OAP65360.1 - 0.52 10.2 1.4 0.8 9.6 0.0 1.9 2 0 0 2 2 2 0 Glutamine synthetase C-terminal domain MFS_1 PF07690.16 OAP65361.1 - 3.5e-45 154.5 48.6 9.9e-44 149.7 28.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAP65361.1 - 7e-08 31.7 10.1 7e-08 31.7 10.1 3.2 2 1 0 3 3 3 2 Sugar (and other) transporter OATP PF03137.20 OAP65361.1 - 0.0013 17.1 7.6 0.0014 17.0 0.4 2.9 1 1 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family VIT1 PF01988.19 OAP65361.1 - 0.016 15.1 0.6 0.016 15.1 0.6 2.0 2 0 0 2 2 2 0 VIT family PT PF04886.12 OAP65362.1 - 0.051 13.1 63.7 0.32 10.6 7.7 7.7 4 2 1 5 5 5 0 PT repeat G_glu_transpept PF01019.21 OAP65363.1 - 1.5e-138 462.8 0.1 1.8e-138 462.5 0.1 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Peptidase_S10 PF00450.22 OAP65364.1 - 1.2e-85 288.4 0.0 1.6e-85 288.1 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Glyoxalase PF00903.25 OAP65365.1 - 1.9e-10 41.0 1.5 1.2e-06 28.8 1.0 2.7 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 OAP65365.1 - 2.1e-05 24.7 0.2 0.0056 16.9 0.0 2.5 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily FAA_hydrolase PF01557.18 OAP65366.1 - 9.4e-61 205.3 0.0 1.2e-60 204.9 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Catalase PF00199.19 OAP65367.1 - 1.3e-171 570.9 0.1 1.7e-171 570.6 0.1 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 OAP65367.1 - 3.2e-15 56.1 0.0 8e-15 54.8 0.0 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive YscO PF07321.12 OAP65367.1 - 0.22 11.5 0.1 0.39 10.7 0.1 1.3 1 0 0 1 1 1 0 Type III secretion protein YscO COesterase PF00135.28 OAP65368.1 - 4.1e-88 296.5 0.0 5.9e-88 296.0 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAP65368.1 - 0.00056 19.8 0.1 0.0015 18.4 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OAP65368.1 - 0.0019 17.7 0.1 0.0042 16.6 0.1 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Med1 PF10744.9 OAP65369.1 - 1.8e-79 267.8 0.0 2.1e-79 267.5 0.0 1.1 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 Sugar_tr PF00083.24 OAP65370.1 - 2e-109 366.4 22.2 2.5e-109 366.1 22.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP65370.1 - 5.6e-19 68.3 28.4 3.6e-14 52.5 2.7 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily NTP_transf_9 PF04248.12 OAP65371.1 - 5.6e-37 125.5 0.1 2.9e-30 104.0 0.1 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF427) ECR1_N PF14382.6 OAP65374.1 - 1.1e-12 47.5 0.0 3e-12 46.1 0.0 1.8 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region KH_6 PF15985.5 OAP65374.1 - 1.1e-05 25.6 0.3 2.3e-05 24.7 0.3 1.5 1 0 0 1 1 1 1 KH domain EXOSC1 PF10447.9 OAP65374.1 - 0.0015 19.1 2.4 0.46 11.1 0.1 3.2 3 1 0 3 3 3 2 Exosome component EXOSC1/CSL4 Ribo_biogen_C PF04034.13 OAP65375.1 - 3.5e-51 172.2 0.0 4.8e-51 171.8 0.0 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 OAP65375.1 - 7.9e-10 38.4 0.3 1.8e-09 37.2 0.3 1.6 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI PPV_E1_N PF00524.18 OAP65375.1 - 0.11 12.9 3.4 0.17 12.3 2.2 1.9 1 1 0 1 1 1 0 E1 Protein, N terminal domain Zn_clus PF00172.18 OAP65376.1 - 0.00013 22.0 3.7 0.00024 21.1 3.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NUDE_C PF04880.13 OAP65376.1 - 0.075 13.5 1.6 0.24 11.9 1.6 1.8 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region bZIP_1 PF00170.21 OAP65377.1 - 1.4e-06 28.3 6.8 2.1e-06 27.7 6.8 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 OAP65377.1 - 0.0063 16.6 7.3 0.088 12.9 7.3 2.3 1 1 0 1 1 1 1 Basic region leucine zipper ATG16 PF08614.11 OAP65377.1 - 0.0073 16.6 7.7 0.0099 16.1 7.7 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) DUF2383 PF09537.10 OAP65377.1 - 0.017 15.5 0.7 0.034 14.5 0.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2383) AMP-binding PF00501.28 OAP65378.1 - 3.6e-73 246.6 0.0 4.5e-73 246.3 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAP65378.1 - 2.9e-16 60.2 0.1 5.9e-16 59.2 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Acetyltransf_1 PF00583.25 OAP65379.1 - 2.7e-05 24.4 0.0 8.2e-05 22.8 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OAP65379.1 - 6.4e-05 23.3 0.0 0.00024 21.5 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OAP65379.1 - 8.6e-05 22.5 0.0 0.00017 21.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAP65379.1 - 0.15 12.1 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_4 PF13420.7 OAP65379.1 - 0.2 11.8 0.0 0.47 10.6 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain ATG22 PF11700.8 OAP65381.1 - 1e-128 430.0 25.2 1.2e-128 429.7 25.2 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 OAP65381.1 - 4e-14 52.3 27.5 7.9e-08 31.6 1.5 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily FRQ PF09421.10 OAP65383.1 - 5e-96 322.8 46.4 1.4e-89 301.5 39.7 3.7 2 2 1 3 3 3 3 Frequency clock protein CoA_trans PF01144.23 OAP65384.1 - 1.5e-100 335.0 1.1 1.2e-60 204.7 0.6 2.0 2 0 0 2 2 2 2 Coenzyme A transferase EIIBC-GUT_N PF03612.14 OAP65384.1 - 0.032 14.0 0.5 0.57 9.9 0.2 2.3 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus HET PF06985.11 OAP65386.1 - 7.3e-32 110.7 0.0 2.4e-31 109.0 0.0 1.9 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Hamartin PF04388.12 OAP65387.1 - 0.85 8.2 3.5 0.87 8.2 3.5 1.0 1 0 0 1 1 1 0 Hamartin protein INO80_Ies4 PF08193.11 OAP65387.1 - 1.4 8.9 10.5 2 8.4 10.5 1.2 1 0 0 1 1 1 0 INO80 complex subunit Ies4 SOG2 PF10428.9 OAP65387.1 - 3.4 6.8 13.7 4.4 6.4 13.7 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein VSP PF03302.13 OAP65388.1 - 1.4e-05 24.1 0.9 2e-05 23.6 0.9 1.1 1 0 0 1 1 1 1 Giardia variant-specific surface protein SKG6 PF08693.10 OAP65388.1 - 7.4e-05 22.1 2.1 0.00015 21.1 2.1 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Podoplanin PF05808.11 OAP65388.1 - 8.1e-05 22.8 0.0 0.00013 22.1 0.0 1.3 1 0 0 1 1 1 1 Podoplanin LapA_dom PF06305.11 OAP65388.1 - 0.00055 19.7 0.7 0.001 18.9 0.7 1.3 1 0 0 1 1 1 1 Lipopolysaccharide assembly protein A domain DUF2613 PF11021.8 OAP65388.1 - 0.0009 19.3 0.3 0.0028 17.7 0.3 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF2613) Amnionless PF14828.6 OAP65388.1 - 0.013 14.4 0.0 0.019 13.8 0.0 1.2 1 0 0 1 1 1 0 Amnionless Nitrate_red_gam PF02665.14 OAP65388.1 - 0.015 14.8 0.2 0.023 14.3 0.2 1.2 1 0 0 1 1 1 0 Nitrate reductase gamma subunit EphA2_TM PF14575.6 OAP65388.1 - 0.021 15.7 0.0 0.041 14.8 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4448 PF14610.6 OAP65388.1 - 0.024 14.4 0.0 0.038 13.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DUF4690 PF15756.5 OAP65388.1 - 0.073 13.7 0.1 0.17 12.5 0.1 1.6 1 0 0 1 1 1 0 Small Novel Rich in Cartilage CYYR1 PF10873.8 OAP65388.1 - 0.11 12.9 1.3 0.16 12.4 0.0 1.8 2 1 0 2 2 2 0 Cysteine and tyrosine-rich protein 1 adh_short PF00106.25 OAP65389.1 - 7.4e-35 120.2 0.0 1.2e-34 119.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP65389.1 - 3.1e-20 72.7 0.0 5.1e-20 72.0 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP65389.1 - 2.4e-06 27.6 0.0 8.8e-06 25.8 0.0 1.7 1 1 0 1 1 1 1 KR domain TrkA_N PF02254.18 OAP65389.1 - 0.1 12.9 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain A2M PF00207.22 OAP65390.1 - 0.023 14.6 0.4 1 9.2 0.0 2.7 3 0 0 3 3 3 0 Alpha-2-macroglobulin family AA_permease_2 PF13520.6 OAP65391.1 - 2.9e-59 201.0 47.0 3.6e-59 200.7 47.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAP65391.1 - 3.2e-28 98.5 41.3 4.1e-28 98.2 41.3 1.0 1 0 0 1 1 1 1 Amino acid permease Tweety PF04906.13 OAP65391.1 - 0.04 12.6 0.3 0.1 11.3 0.3 1.7 1 0 0 1 1 1 0 Tweety DUF5427 PF10310.9 OAP65393.1 - 1.9e-171 571.1 0.1 2.4e-171 570.8 0.1 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5427) Flu_M1_C PF08289.11 OAP65393.1 - 0.06 13.6 0.1 0.17 12.1 0.1 1.7 1 0 0 1 1 1 0 Influenza Matrix protein (M1) C-terminal domain Ndc1_Nup PF09531.10 OAP65393.1 - 4.8 5.7 6.3 9 4.8 6.3 1.5 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SOG2 PF10428.9 OAP65393.1 - 8.5 5.5 11.7 14 4.7 11.7 1.4 1 0 0 1 1 1 0 RAM signalling pathway protein Transp_cyt_pur PF02133.15 OAP65395.1 - 1.6e-25 89.8 39.2 2.4e-25 89.2 39.2 1.2 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Arylsulfotrans PF05935.11 OAP65396.1 - 4.9e-21 75.1 0.0 1.2e-10 40.9 0.0 2.1 1 1 1 2 2 2 2 Arylsulfotransferase (ASST) Arylsulfotran_2 PF14269.6 OAP65396.1 - 1.2e-18 67.6 0.0 2.1e-18 66.8 0.0 1.4 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) PQQ_2 PF13360.6 OAP65396.1 - 0.0012 18.5 0.0 0.003 17.2 0.0 1.7 1 1 0 1 1 1 1 PQQ-like domain THUMP PF02926.17 OAP65397.1 - 1.5e-10 41.4 0.3 3.2e-10 40.3 0.3 1.6 1 1 0 1 1 1 1 THUMP domain SOAR PF16533.5 OAP65398.1 - 0.0016 18.4 8.1 0.0066 16.4 1.2 3.0 2 1 0 2 2 2 1 STIM1 Orai1-activating region DUF3398 PF11878.8 OAP65398.1 - 0.093 13.2 0.0 0.36 11.3 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3398) OAF PF14941.6 OAP65398.1 - 0.097 12.1 1.7 0.18 11.2 1.0 1.7 1 1 0 1 1 1 0 Transcriptional regulator, Out at first UPF0242 PF06785.11 OAP65398.1 - 0.41 10.7 14.5 0.068 13.3 4.7 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Spc7 PF08317.11 OAP65398.1 - 0.55 9.1 18.9 0.22 10.3 2.0 3.0 2 1 1 3 3 3 0 Spc7 kinetochore protein Med9 PF07544.13 OAP65398.1 - 0.94 9.6 7.5 18 5.5 0.8 3.6 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 DUF4407 PF14362.6 OAP65398.1 - 1.2 8.5 10.9 1.5 8.1 5.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) TMF_DNA_bd PF12329.8 OAP65398.1 - 1.4 9.0 10.8 1.7 8.7 3.2 3.1 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF948 PF06103.11 OAP65398.1 - 1.5 9.1 5.1 14 6.0 0.0 3.7 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) MPS2 PF17060.5 OAP65398.1 - 3.4 6.8 9.7 0.075 12.3 2.7 1.7 2 0 0 2 2 2 0 Monopolar spindle protein 2 DUF4200 PF13863.6 OAP65398.1 - 4.4 7.7 13.8 6 7.3 1.5 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) FAM76 PF16046.5 OAP65398.1 - 9.5 5.5 11.5 3.3 7.0 0.7 2.4 2 0 0 2 2 2 0 FAM76 protein GFO_IDH_MocA PF01408.22 OAP65400.1 - 1.7e-14 54.7 0.0 2.7e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Ribonuclease_T2 PF00445.18 OAP65401.1 - 7.3e-36 124.1 0.1 1.7e-35 122.9 0.0 1.5 2 0 0 2 2 2 1 Ribonuclease T2 family MutS_V PF00488.21 OAP65404.1 - 1.1e-75 253.9 0.2 3.6e-75 252.1 0.1 2.0 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.18 OAP65404.1 - 9.3e-37 127.1 0.7 9.3e-37 127.1 0.7 1.8 2 0 0 2 2 2 1 MutS domain III MutS_II PF05188.17 OAP65404.1 - 2.2e-19 70.1 0.2 1e-18 67.9 0.0 2.3 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.18 OAP65404.1 - 2.5e-18 66.2 0.5 8.9e-18 64.4 0.5 2.0 1 0 0 1 1 1 1 MutS family domain IV MutS_I PF01624.20 OAP65404.1 - 7e-15 55.2 0.0 1.5e-13 51.0 0.0 2.7 3 0 0 3 3 3 1 MutS domain I AAA_27 PF13514.6 OAP65404.1 - 0.022 14.4 0.0 0.083 12.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain TetR_C_7 PF14246.6 OAP65404.1 - 0.039 14.0 0.6 1.5 8.9 0.0 3.2 4 0 0 4 4 4 0 AefR-like transcriptional repressor, C-terminal domain TipAS PF07739.13 OAP65404.1 - 7.8 7.1 7.0 4.4 7.9 2.7 2.9 3 0 0 3 3 3 0 TipAS antibiotic-recognition domain DUF2183 PF09949.9 OAP65405.1 - 1.1e-20 73.9 0.2 5.8e-20 71.5 0.0 2.3 1 1 1 2 2 2 1 Uncharacterized conserved protein (DUF2183) B PF02216.16 OAP65405.1 - 0.14 12.1 0.1 0.32 11.0 0.0 1.6 2 0 0 2 2 2 0 B domain Aa_trans PF01490.18 OAP65406.1 - 2.3e-11 43.1 36.5 3.4e-08 32.6 23.5 2.2 1 1 1 2 2 2 2 Transmembrane amino acid transporter protein DUF2157 PF09925.9 OAP65406.1 - 0.015 15.1 0.8 0.059 13.2 0.8 2.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) Glyco_hydro_76 PF03663.14 OAP65407.1 - 5.6e-143 476.9 20.2 6.9e-143 476.6 20.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 TetR_C_3 PF08362.11 OAP65407.1 - 0.32 10.9 0.9 0.57 10.1 0.2 1.7 2 0 0 2 2 2 0 YcdC-like protein, C-terminal region CSN8_PSD8_EIF3K PF10075.9 OAP65408.1 - 2.3e-42 144.4 0.0 3.1e-42 144.0 0.0 1.2 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family XPC-binding PF09280.11 OAP65408.1 - 0.021 14.5 0.3 0.93 9.3 0.0 2.3 2 0 0 2 2 2 0 XPC-binding domain F-box-like PF12937.7 OAP65409.1 - 1.8e-15 56.6 0.4 1.7e-14 53.4 0.1 2.6 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 OAP65409.1 - 3.9e-06 26.6 3.2 4.3e-06 26.5 0.6 2.4 2 0 0 2 2 2 1 F-box domain F-box_4 PF15966.5 OAP65409.1 - 0.0001 22.2 0.5 0.00076 19.4 0.0 2.6 3 0 0 3 3 3 1 F-box LRR_4 PF12799.7 OAP65409.1 - 1 9.9 9.3 4.8 7.7 0.3 4.9 6 0 0 6 6 6 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OAP65409.1 - 1.2 10.0 4.2 9 7.3 0.6 3.9 4 1 0 4 4 4 0 Leucine Rich Repeat MFS_1 PF07690.16 OAP65410.1 - 1.5e-29 103.0 40.2 1.5e-29 103.0 40.2 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Pil1 PF13805.6 OAP65413.1 - 3.9e-101 338.0 7.5 5.1e-101 337.6 7.5 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 CHAD PF05235.14 OAP65413.1 - 0.049 13.6 1.0 0.087 12.8 1.0 1.4 1 0 0 1 1 1 0 CHAD domain BAR_3 PF16746.5 OAP65413.1 - 0.26 11.0 5.2 0.31 10.7 1.2 2.3 1 1 1 2 2 2 0 BAR domain of APPL family DUF4633 PF15464.6 OAP65413.1 - 0.63 10.2 5.2 0.35 11.0 0.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4633) p450 PF00067.22 OAP65414.1 - 1.1e-45 156.2 0.0 3e-30 105.4 0.0 2.7 2 2 0 2 2 2 2 Cytochrome P450 Potass_KdpF PF09604.10 OAP65414.1 - 0.55 10.3 2.6 1.6 8.8 2.6 1.8 1 0 0 1 1 1 0 F subunit of K+-transporting ATPase (Potass_KdpF) Macoilin PF09726.9 OAP65415.1 - 6 5.3 8.8 7.6 5.0 8.8 1.1 1 0 0 1 1 1 0 Macoilin family APG9 PF04109.16 OAP65416.1 - 3.3e-197 656.2 13.2 3.9e-197 656.0 13.1 1.0 1 0 0 1 1 1 1 Autophagy protein Apg9 Zn_clus PF00172.18 OAP65417.1 - 4.5e-07 29.9 9.0 4.5e-07 29.9 9.0 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PP_kinase_C PF13090.6 OAP65417.1 - 0.13 11.7 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Polyphosphate kinase C-terminal domain 2 Glyco_hydro_47 PF01532.20 OAP65418.1 - 4.1e-184 612.8 0.0 5e-184 612.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF2013 PF09431.10 OAP65419.1 - 9.6e-54 181.3 0.5 1.6e-53 180.6 0.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2013) DUF4575 PF15143.6 OAP65419.1 - 8.2 6.7 8.0 4.2 7.6 2.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4575) Glyco_hydro_17 PF00332.18 OAP65420.1 - 7e-05 22.6 0.7 0.00038 20.1 0.1 2.0 1 1 0 2 2 2 1 Glycosyl hydrolases family 17 AAA PF00004.29 OAP65421.1 - 2.6e-37 128.2 0.0 4.6e-37 127.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OAP65421.1 - 2.7e-09 36.7 0.0 7.4e-09 35.3 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain Vps4_C PF09336.10 OAP65421.1 - 1.5e-08 34.5 0.1 4.2e-07 29.9 0.0 3.2 3 0 0 3 3 3 1 Vps4 C terminal oligomerisation domain AAA_2 PF07724.14 OAP65421.1 - 2e-05 24.7 0.0 3.3e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 OAP65421.1 - 3.2e-05 24.2 1.3 0.0005 20.4 0.1 2.7 2 1 1 3 3 3 1 AAA domain RuvB_N PF05496.12 OAP65421.1 - 6.9e-05 22.7 0.0 0.00013 21.8 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 OAP65421.1 - 0.00022 21.6 1.5 0.0028 18.0 0.8 3.2 2 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 OAP65421.1 - 0.00046 20.2 0.0 0.0011 18.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 OAP65421.1 - 0.0011 18.3 0.0 0.0022 17.3 0.0 1.4 1 1 0 1 1 1 1 TIP49 P-loop domain IstB_IS21 PF01695.17 OAP65421.1 - 0.0044 16.8 0.0 0.0098 15.6 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 OAP65421.1 - 0.0047 16.3 0.1 0.0096 15.3 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 OAP65421.1 - 0.016 15.4 0.0 0.051 13.7 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 OAP65421.1 - 0.016 14.7 0.1 0.19 11.3 0.1 2.4 1 1 0 2 2 2 0 AAA domain AAA_24 PF13479.6 OAP65421.1 - 0.021 14.5 0.0 0.12 12.0 0.0 2.2 3 0 0 3 3 3 0 AAA domain AAA_14 PF13173.6 OAP65421.1 - 0.025 14.6 0.0 0.051 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 OAP65421.1 - 0.042 13.0 0.0 0.073 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_18 PF13238.6 OAP65421.1 - 0.063 13.8 0.0 0.26 11.8 0.0 2.2 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 OAP65421.1 - 0.1 12.1 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 OAP65421.1 - 0.13 12.1 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Sigma54_activat PF00158.26 OAP65421.1 - 0.16 11.7 0.0 0.71 9.6 0.0 2.0 1 1 1 2 2 2 0 Sigma-54 interaction domain TniB PF05621.11 OAP65421.1 - 0.18 11.2 0.0 5.7 6.3 0.0 2.4 1 1 1 2 2 2 0 Bacterial TniB protein PhoH PF02562.16 OAP65421.1 - 0.24 10.8 0.0 0.54 9.7 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein Mito_carr PF00153.27 OAP65422.1 - 9.2e-66 217.8 4.9 2e-23 82.1 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein IBR PF01485.21 OAP65423.1 - 2.1e-18 66.3 41.5 2.6e-09 37.2 2.0 4.4 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain W2 PF02020.18 OAP65423.1 - 4.7e-17 61.9 5.0 6.8e-17 61.4 2.6 2.5 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.24 OAP65423.1 - 3.7e-09 35.9 14.8 0.0016 18.1 2.3 3.8 1 1 4 5 5 5 5 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.23 OAP65423.1 - 3.7e-05 23.4 0.0 8.2e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyl transferase zf-C3HC4 PF00097.25 OAP65423.1 - 0.00048 19.9 4.2 0.00048 19.9 4.2 4.2 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) Hexapep_2 PF14602.6 OAP65423.1 - 0.0008 19.1 13.5 0.023 14.4 1.6 3.5 2 1 1 3 3 3 3 Hexapeptide repeat of succinyl-transferase NTP_transf_3 PF12804.7 OAP65423.1 - 0.0019 18.6 0.0 0.0052 17.2 0.0 1.7 1 0 0 1 1 1 1 MobA-like NTP transferase domain zf-C3HC4_2 PF13923.6 OAP65423.1 - 0.0024 17.7 3.8 0.0024 17.7 3.8 4.6 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAP65423.1 - 0.003 17.9 4.9 0.003 17.9 4.9 3.8 2 1 1 3 3 3 1 Ring finger domain zf-RING_5 PF14634.6 OAP65423.1 - 0.0031 17.4 7.0 0.0031 17.4 7.0 3.4 2 1 1 3 3 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 OAP65423.1 - 0.006 16.6 2.7 0.006 16.6 2.7 3.8 3 0 0 3 3 3 1 RING-type zinc-finger Fucokinase PF07959.12 OAP65423.1 - 0.072 12.0 0.1 0.13 11.2 0.1 1.3 1 0 0 1 1 1 0 L-fucokinase CRAL_TRIO PF00650.20 OAP65424.1 - 7.5e-40 136.3 0.0 1.2e-39 135.5 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 OAP65424.1 - 2.7e-07 30.6 0.3 6e-07 29.6 0.3 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 OAP65424.1 - 0.0001 22.5 0.0 0.00024 21.2 0.0 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Mis14 PF08641.12 OAP65425.1 - 4.2e-14 53.0 0.7 4.2e-14 53.0 0.7 2.0 2 1 0 2 2 2 1 Kinetochore protein Mis14 like ubiquitin PF00240.23 OAP65426.1 - 4.4e-34 116.0 0.6 7.9e-34 115.2 0.6 1.4 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.19 OAP65426.1 - 9.1e-26 89.8 3.3 9.1e-26 89.8 3.3 2.0 2 0 0 2 2 2 1 Ribosomal protein S27a Rad60-SLD PF11976.8 OAP65426.1 - 2.7e-16 59.2 0.7 4.9e-16 58.3 0.7 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 OAP65426.1 - 2.7e-05 24.5 0.4 0.00013 22.4 0.1 2.1 2 1 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 OAP65426.1 - 0.0007 19.7 0.7 0.0016 18.5 0.7 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 OAP65426.1 - 0.0041 17.4 0.9 0.0075 16.6 0.1 1.7 1 1 1 2 2 2 1 Ubiquitin-like domain TBK1_ULD PF18396.1 OAP65426.1 - 0.0054 16.6 0.0 0.0082 16.1 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain DUF2407 PF10302.9 OAP65426.1 - 0.013 16.1 0.9 0.018 15.6 0.9 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 OAP65426.1 - 0.021 14.9 1.0 5.9 7.0 0.2 2.4 2 0 0 2 2 2 0 Ubiquitin-like domain zf-H2C2_2 PF13465.6 OAP65427.1 - 1.7e-07 31.3 12.1 0.0039 17.5 0.3 3.7 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 OAP65427.1 - 1.8e-07 31.2 22.5 0.006 17.0 1.4 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAP65427.1 - 0.00013 22.5 20.0 0.26 12.2 5.9 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger Bunya_G2 PF03563.13 OAP65427.1 - 0.35 10.1 3.5 0.54 9.5 3.5 1.2 1 0 0 1 1 1 0 Bunyavirus glycoprotein G2 zf-C2H2_11 PF16622.5 OAP65427.1 - 0.51 10.2 10.9 1.3 8.8 3.4 2.6 2 0 0 2 2 2 0 zinc-finger C2H2-type IFT43 PF15305.6 OAP65428.1 - 0.048 13.8 0.8 0.062 13.5 0.8 1.2 1 0 0 1 1 1 0 Intraflagellar transport protein 43 Transthyretin PF00576.21 OAP65429.1 - 1.3e-33 116.0 0.0 1.5e-33 115.8 0.0 1.0 1 0 0 1 1 1 1 HIUase/Transthyretin family Sugar_tr PF00083.24 OAP65430.1 - 7.5e-84 282.2 16.3 9.8e-84 281.8 16.3 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP65430.1 - 7.8e-23 81.0 50.2 3.7e-16 59.0 25.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Acetyltransf_CG PF14542.6 OAP65431.1 - 0.021 14.9 0.0 0.047 13.8 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_1 PF00583.25 OAP65431.1 - 0.063 13.5 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Romo1 PF10247.9 OAP65431.1 - 0.24 11.8 0.2 16 5.9 0.1 2.3 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 adh_short PF00106.25 OAP65432.1 - 0.031 13.7 0.0 0.062 12.8 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase Sacchrp_dh_NADP PF03435.18 OAP65432.1 - 0.11 12.7 0.1 0.2 11.9 0.1 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain RRM_1 PF00076.22 OAP65433.1 - 6.6e-50 166.8 0.0 1.1e-17 63.5 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OAP65433.1 - 1.7e-05 24.4 0.0 0.051 13.2 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 OAP65433.1 - 0.00011 22.1 0.1 1.5 9.0 0.0 4.1 3 2 0 3 3 3 2 Limkain b1 RRM_3 PF08777.11 OAP65433.1 - 0.0019 18.2 0.0 12 6.0 0.0 3.5 3 1 0 3 3 3 2 RNA binding motif SPOR PF05036.13 OAP65433.1 - 0.0021 18.4 0.2 0.5 10.8 0.1 3.6 3 1 1 4 4 4 1 Sporulation related domain ATP-grasp_2 PF08442.10 OAP65433.1 - 0.0024 17.5 0.0 0.28 10.7 0.0 2.9 3 0 0 3 3 3 1 ATP-grasp domain RRM_Rrp7 PF17799.1 OAP65433.1 - 0.005 16.6 0.0 2.6 7.8 0.0 2.9 3 0 0 3 3 3 1 Rrp7 RRM-like N-terminal domain PknH_C PF14032.6 OAP65433.1 - 0.042 13.7 0.3 21 4.9 0.0 3.2 3 0 0 3 3 3 0 PknH-like extracellular domain COQ9 PF08511.11 OAP65434.1 - 2.8e-33 113.5 0.3 5.1e-33 112.7 0.3 1.4 1 0 0 1 1 1 1 COQ9 UPF0242 PF06785.11 OAP65435.1 - 0.028 14.5 0.2 0.048 13.8 0.2 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus AAA_13 PF13166.6 OAP65435.1 - 0.034 12.8 0.2 0.046 12.4 0.2 1.1 1 0 0 1 1 1 0 AAA domain BBP1_C PF15272.6 OAP65435.1 - 0.049 13.4 1.9 0.12 12.2 1.9 1.6 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal ATG16 PF08614.11 OAP65435.1 - 0.48 10.6 16.8 0.44 10.7 9.7 2.5 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) TFIIA PF03153.13 OAP65435.1 - 0.51 10.3 6.4 0.64 10.0 6.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SlyX PF04102.12 OAP65435.1 - 0.59 10.8 13.3 3.1 8.5 2.0 3.9 2 1 2 4 4 4 0 SlyX DUF2730 PF10805.8 OAP65435.1 - 0.66 10.1 3.3 14 5.8 0.1 3.2 2 1 0 3 3 3 0 Protein of unknown function (DUF2730) Exonuc_VII_L PF02601.15 OAP65435.1 - 0.95 9.0 11.7 0.33 10.5 7.1 2.0 2 0 0 2 2 2 0 Exonuclease VII, large subunit Cep57_MT_bd PF06657.13 OAP65435.1 - 1.2 9.7 5.1 2.3 8.7 3.6 2.3 2 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 BLOC1_2 PF10046.9 OAP65435.1 - 4.4 7.7 6.5 11 6.4 0.6 2.9 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Bromodomain PF00439.25 OAP65436.1 - 6.1e-38 128.8 4.4 1e-18 67.2 0.6 2.6 2 0 0 2 2 2 2 Bromodomain BAH PF01426.18 OAP65436.1 - 1.2e-17 63.9 1.1 1.2e-17 63.9 1.1 2.0 2 0 0 2 2 2 1 BAH domain GCIP PF13324.6 OAP65436.1 - 2.1 7.9 10.0 1.7 8.2 3.9 2.4 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting OTU PF02338.19 OAP65437.1 - 2.2e-08 34.7 0.0 4.4e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 OTU-like cysteine protease UBX PF00789.20 OAP65437.1 - 0.025 14.8 0.0 0.053 13.7 0.0 1.6 1 0 0 1 1 1 0 UBX domain Abhydrolase_3 PF07859.13 OAP65438.1 - 2.2e-49 168.2 0.0 2.7e-49 167.9 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 OAP65438.1 - 2.2e-10 40.0 0.0 9.3e-10 38.0 0.0 1.7 1 1 0 1 1 1 1 Carboxylesterase family Say1_Mug180 PF10340.9 OAP65438.1 - 0.00038 19.4 0.0 0.00048 19.1 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_1 PF00561.20 OAP65438.1 - 0.0041 16.8 0.0 0.0058 16.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 OAP65438.1 - 0.063 12.9 0.1 0.31 10.6 0.1 2.1 2 1 0 2 2 2 0 Putative esterase Peptidase_S9 PF00326.21 OAP65438.1 - 0.077 12.5 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 OAP65438.1 - 0.1 13.2 0.1 0.17 12.5 0.1 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family COG6 PF06419.11 OAP65439.1 - 3.6e-157 524.3 1.3 4.1e-157 524.1 1.3 1.1 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 DUF4570 PF15134.6 OAP65439.1 - 0.0059 16.6 0.5 0.24 11.4 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4570) DUF885 PF05960.11 OAP65439.1 - 0.071 12.7 4.1 0.34 10.5 0.5 2.8 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF885) DUF4164 PF13747.6 OAP65439.1 - 9.1 6.6 8.5 3.9 7.8 0.1 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF4164) Redoxin PF08534.10 OAP65440.1 - 4.6e-29 101.0 0.0 5.1e-29 100.9 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 OAP65440.1 - 3.7e-08 33.3 0.0 4.6e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family HSF_DNA-bind PF00447.17 OAP65441.1 - 1.1e-31 109.3 2.6 1.1e-31 109.3 2.6 1.7 2 0 0 2 2 2 1 HSF-type DNA-binding Response_reg PF00072.24 OAP65441.1 - 1.3e-23 83.3 0.1 3.4e-23 81.9 0.1 1.7 1 0 0 1 1 1 1 Response regulator receiver domain Ets PF00178.22 OAP65441.1 - 0.09 13.3 0.2 0.3 11.6 0.0 1.9 2 0 0 2 2 2 0 Ets-domain Herpes_heli_pri PF05774.11 OAP65441.1 - 0.091 13.0 0.1 0.23 11.7 0.1 1.6 1 0 0 1 1 1 0 Herpesvirus helicase-primase complex component BLOC1_2 PF10046.9 OAP65441.1 - 0.39 11.0 6.3 0.38 11.1 4.5 2.0 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DivIC PF04977.15 OAP65441.1 - 2.4 8.0 10.8 1.2 8.9 1.9 2.4 2 0 0 2 2 2 0 Septum formation initiator TORC_N PF12884.7 OAP65441.1 - 5.8 7.8 8.5 1.3 9.8 0.4 3.1 2 0 0 2 2 2 0 Transducer of regulated CREB activity, N terminus BolA PF01722.18 OAP65442.1 - 1e-15 57.7 0.0 1.6e-15 57.1 0.0 1.3 1 0 0 1 1 1 1 BolA-like protein NIF3 PF01784.18 OAP65443.1 - 3.5e-56 190.6 0.0 5e-56 190.1 0.0 1.2 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) AA_permease_C PF13906.6 OAP65444.1 - 1.6 8.8 7.0 2.5 8.3 7.0 1.3 1 0 0 1 1 1 0 C-terminus of AA_permease Asp PF00026.23 OAP65445.1 - 1.3e-58 198.9 2.1 1.3e-58 198.9 2.1 1.7 2 0 0 2 2 2 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OAP65445.1 - 1.9e-10 41.2 2.3 3e-07 30.9 0.0 4.2 2 2 2 4 4 4 2 Xylanase inhibitor N-terminal Kinesin PF00225.23 OAP65448.1 - 4.5e-85 285.5 0.1 6.7e-85 284.9 0.1 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 OAP65448.1 - 1.5e-23 83.4 0.0 2.7e-23 82.6 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding HHH_3 PF12836.7 OAP65448.1 - 1.8e-06 28.1 0.0 5.9e-06 26.5 0.0 1.9 1 1 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.6 OAP65448.1 - 0.00012 22.6 0.7 0.19 12.3 0.1 2.5 1 1 1 2 2 2 2 Helix-hairpin-helix domain HHH PF00633.23 OAP65448.1 - 0.0021 17.8 0.1 0.58 10.1 0.0 2.7 2 0 0 2 2 2 1 Helix-hairpin-helix motif RNA_pol_A_CTD PF03118.15 OAP65448.1 - 0.055 13.2 0.1 0.19 11.5 0.0 2.0 2 0 0 2 2 2 0 Bacterial RNA polymerase, alpha chain C terminal domain PGA2 PF07543.12 OAP65448.1 - 0.81 9.7 6.0 1.7 8.6 6.0 1.5 1 0 0 1 1 1 0 Protein trafficking PGA2 Nucleo_P87 PF07267.11 OAP65448.1 - 4.3 6.1 8.7 14 4.4 7.2 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 Abhydrolase_1 PF00561.20 OAP65451.1 - 6.2e-11 42.4 0.0 4.7e-10 39.6 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAP65451.1 - 7.3e-10 39.8 1.1 1.8e-09 38.5 1.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAP65451.1 - 0.00012 21.5 0.0 0.00021 20.7 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 OAP65451.1 - 0.0009 19.0 0.0 0.0012 18.5 0.0 1.2 1 0 0 1 1 1 1 Putative esterase DLH PF01738.18 OAP65451.1 - 0.14 11.7 0.2 0.36 10.3 0.1 1.7 1 1 1 2 2 2 0 Dienelactone hydrolase family Cnn_1N PF07989.11 OAP65452.1 - 1e-24 86.4 8.3 1e-24 86.4 8.3 16.7 7 5 5 12 12 12 3 Centrosomin N-terminal motif 1 PACT_coil_coil PF10495.9 OAP65452.1 - 1.3e-18 67.3 0.6 1.3e-18 67.3 0.6 4.4 3 1 0 3 3 3 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein Fez1 PF06818.15 OAP65452.1 - 2.1e-06 28.4 200.0 0.011 16.3 14.2 8.5 2 2 6 8 8 8 4 Fez1 CENP-F_leu_zip PF10473.9 OAP65452.1 - 0.001 19.1 21.1 0.001 19.1 21.1 13.0 2 1 9 12 12 12 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ADIP PF11559.8 OAP65452.1 - 0.0029 17.7 11.5 0.0029 17.7 11.5 12.6 5 4 5 11 11 11 3 Afadin- and alpha -actinin-Binding TMF_TATA_bd PF12325.8 OAP65452.1 - 0.0053 17.0 16.7 0.0053 17.0 16.7 13.5 2 2 12 14 14 14 2 TATA element modulatory factor 1 TATA binding Spc7 PF08317.11 OAP65452.1 - 0.086 11.7 209.7 0.048 12.5 10.6 10.7 1 1 10 11 11 11 0 Spc7 kinetochore protein Polo_box_2 PF18531.1 OAP65452.1 - 1.2 9.2 4.5 0.98 9.6 0.4 2.8 2 0 0 2 2 2 0 Polo box domain Filament PF00038.21 OAP65452.1 - 1.5 8.3 195.2 0.18 11.3 10.9 8.8 1 1 7 8 8 8 0 Intermediate filament protein SGT1 PF07093.11 OAP65453.1 - 1.5e-95 320.9 5.9 2.1e-85 287.4 0.1 2.0 1 1 1 2 2 2 2 SGT1 protein DUF1373 PF07117.11 OAP65453.1 - 0.076 13.0 0.2 0.15 12.0 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1373) EHN PF06441.12 OAP65454.1 - 6.8e-34 116.5 2.4 3.5e-33 114.2 0.2 2.4 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 OAP65454.1 - 7.8e-13 48.7 0.0 1.3e-12 47.9 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAP65454.1 - 4.7e-05 24.1 0.1 0.00025 21.7 0.1 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family JAB PF01398.21 OAP65455.1 - 3.3e-14 52.9 0.0 6.1e-14 52.0 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease USP8_dimer PF08969.11 OAP65455.1 - 1.8e-11 44.2 0.5 1.8e-11 44.2 0.5 1.8 2 0 0 2 2 2 1 USP8 dimerisation domain Prok-JAB PF14464.6 OAP65455.1 - 2.6e-05 24.0 0.2 9.3e-05 22.2 0.0 2.0 2 0 0 2 2 2 1 Prokaryotic homologs of the JAB domain CorA PF01544.18 OAP65455.1 - 1 8.6 4.0 2.3 7.5 4.0 1.5 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein HGTP_anticodon2 PF12745.7 OAP65455.1 - 1.1 8.7 4.2 1.6 8.2 4.2 1.1 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs WSC PF01822.19 OAP65456.1 - 1e-13 51.3 10.7 2.6e-13 49.9 10.7 1.7 1 0 0 1 1 1 1 WSC domain SKG6 PF08693.10 OAP65456.1 - 1.4e-05 24.4 3.4 1.4e-05 24.4 3.4 1.9 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Gram_pos_anchor PF00746.21 OAP65456.1 - 0.1 12.5 0.3 0.31 11.0 0.3 1.8 1 0 0 1 1 1 0 LPXTG cell wall anchor motif Phage_holin_2_4 PF16082.5 OAP65456.1 - 0.15 11.8 0.4 0.46 10.2 0.4 1.8 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like TBCC PF07986.12 OAP65457.1 - 1e-31 109.2 0.8 1.5e-31 108.6 0.8 1.2 1 0 0 1 1 1 1 Tubulin binding cofactor C TBCC_N PF16752.5 OAP65457.1 - 1.8e-07 31.6 0.0 3.4e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Tubulin-specific chaperone C N-terminal domain RrnaAD PF00398.20 OAP65458.1 - 2.5e-05 23.5 0.0 0.00022 20.4 0.0 2.4 2 1 0 2 2 2 1 Ribosomal RNA adenine dimethylase Isochorismatase PF00857.20 OAP65459.1 - 1.8e-18 67.4 0.7 2e-15 57.4 0.7 3.1 1 1 0 1 1 1 1 Isochorismatase family HET PF06985.11 OAP65461.1 - 7.9e-07 29.5 0.0 8e-05 23.0 0.0 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Pro_CA PF00484.19 OAP65463.1 - 5.2e-07 30.1 0.0 1.8e-06 28.4 0.0 1.8 1 1 0 1 1 1 1 Carbonic anhydrase TPR_19 PF14559.6 OAP65465.1 - 0.005 17.3 0.4 1.6 9.3 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 OAP65465.1 - 0.06 13.6 0.4 0.62 10.4 0.2 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 OAP65465.1 - 0.066 13.4 0.2 1.6 9.1 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Paf67 PF10255.9 OAP65465.1 - 1.6 7.6 5.5 0.29 10.1 0.2 2.2 3 0 0 3 3 3 0 RNA polymerase I-associated factor PAF67 adh_short PF00106.25 OAP65466.1 - 4.1e-29 101.4 0.1 5e-29 101.2 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP65466.1 - 3.6e-25 88.9 0.0 4.4e-25 88.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP65466.1 - 4e-10 39.9 0.1 5e-10 39.6 0.1 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 OAP65466.1 - 0.039 13.8 0.1 0.058 13.3 0.1 1.6 1 1 0 1 1 1 0 NAD(P)H-binding DDE_Tnp_IS1 PF03400.13 OAP65466.1 - 0.08 13.3 0.0 0.13 12.6 0.0 1.3 1 0 0 1 1 1 0 IS1 transposase Ribosomal_L12 PF00542.19 OAP65466.1 - 0.17 12.3 0.0 0.71 10.3 0.0 1.9 1 1 1 2 2 2 0 Ribosomal protein L7/L12 C-terminal domain NifU_N PF01592.16 OAP65467.1 - 1.2e-54 183.9 0.1 1.6e-54 183.5 0.1 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain PC4 PF02229.16 OAP65468.1 - 3.6e-24 84.1 0.5 6e-24 83.4 0.5 1.4 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) HBS1_N PF08938.10 OAP65468.1 - 0.23 11.8 0.0 0.23 11.8 0.0 2.1 1 1 1 2 2 2 0 HBS1 N-terminus Hydantoinase_B PF02538.14 OAP65469.1 - 2e-223 742.5 0.0 2.9e-223 742.0 0.0 1.2 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 OAP65469.1 - 6.9e-105 350.5 0.1 1.9e-104 349.0 0.1 1.8 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 OAP65469.1 - 9.1e-61 204.7 1.0 4.2e-59 199.2 0.0 2.8 3 0 0 3 3 3 1 Hydantoinase/oxoprolinase N-terminal region CdvA PF18822.1 OAP65469.1 - 0.1 12.4 1.0 0.33 10.8 0.4 2.2 2 0 0 2 2 2 0 CdvA-like coiled-coil domain ZYG-11_interact PF05884.12 OAP65469.1 - 0.24 10.8 0.1 0.4 10.1 0.1 1.2 1 0 0 1 1 1 0 Interactor of ZYG-11 Pkinase PF00069.25 OAP65470.1 - 1.2e-70 237.9 0.0 1.5e-70 237.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP65470.1 - 1.6e-42 145.6 0.0 2e-42 145.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAP65470.1 - 8.3e-07 28.6 0.0 4e-06 26.4 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 OAP65470.1 - 0.00034 20.0 0.1 0.0006 19.2 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OAP65470.1 - 0.0034 16.4 0.0 0.005 15.8 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 OAP65470.1 - 0.026 14.1 0.2 0.2 11.2 0.0 2.3 2 1 1 3 3 3 0 RIO1 family FTA2 PF13095.6 OAP65470.1 - 0.062 12.9 0.0 0.27 10.8 0.0 1.9 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 OAP65470.1 - 0.11 12.5 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family TIP41 PF04176.13 OAP65471.1 - 1.7e-68 229.5 0.0 2e-68 229.2 0.0 1.1 1 0 0 1 1 1 1 TIP41-like family SKG6 PF08693.10 OAP65472.1 - 3.1e-05 23.3 0.0 0.0001 21.6 0.0 2.0 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Rax2 PF12768.7 OAP65472.1 - 0.00019 21.0 0.0 0.00034 20.1 0.0 1.4 1 0 0 1 1 1 1 Cortical protein marker for cell polarity Mid2 PF04478.12 OAP65472.1 - 0.025 14.4 0.7 0.025 14.4 0.7 2.4 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor TMEM154 PF15102.6 OAP65472.1 - 1.3 8.9 8.8 0.066 13.1 1.1 2.6 1 1 1 2 2 2 0 TMEM154 protein family VSP PF03302.13 OAP65472.1 - 1.9 7.2 9.1 0.6 8.9 6.3 1.4 1 1 0 1 1 1 0 Giardia variant-specific surface protein CytochromB561_N PF09786.9 OAP65472.1 - 5.7 5.8 10.2 7.5 5.4 10.2 1.2 1 0 0 1 1 1 0 Cytochrome B561, N terminal zf-H2C2 PF09337.10 OAP65473.1 - 1.7e-16 60.2 3.0 3.5e-16 59.1 3.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger Integrase_H2C2 PF17921.1 OAP65473.1 - 1.8e-11 43.9 0.2 3.7e-11 42.9 0.2 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain Acetyltransf_1 PF00583.25 OAP65473.1 - 5.3e-05 23.4 0.0 9.6e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 OAP65473.1 - 0.0022 18.7 0.0 0.0042 17.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OAP65473.1 - 0.009 16.4 0.0 0.022 15.2 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 OAP65473.1 - 0.056 13.6 0.0 0.094 12.8 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PA14 PF07691.12 OAP65473.1 - 0.085 12.7 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 PA14 domain DUF2486 PF10667.9 OAP65473.1 - 3.3 7.9 7.7 6 7.0 7.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2486) Fungal_trans_2 PF11951.8 OAP65474.1 - 1.8e-20 73.2 1.7 2.6e-20 72.6 1.7 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Amidase PF01425.21 OAP65475.1 - 5e-89 299.3 0.0 1.9e-88 297.4 0.0 1.7 1 1 0 1 1 1 1 Amidase DAO PF01266.24 OAP65476.1 - 7.5e-35 121.1 1.6 9.3e-35 120.8 1.6 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 OAP65476.1 - 1.4e-05 24.5 0.0 3.3e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 OAP65476.1 - 0.00028 21.0 0.3 0.0011 19.2 0.2 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 OAP65476.1 - 0.0011 18.1 0.1 0.0021 17.2 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 OAP65476.1 - 0.0022 18.0 0.9 0.024 14.6 0.4 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 OAP65476.1 - 0.0028 16.8 0.6 0.0048 16.0 0.2 1.5 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 OAP65476.1 - 0.0031 16.8 0.2 0.0051 16.1 0.2 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.15 OAP65476.1 - 0.0039 15.8 0.1 0.0057 15.3 0.1 1.2 1 0 0 1 1 1 1 Malate:quinone oxidoreductase (Mqo) Pyr_redox_3 PF13738.6 OAP65476.1 - 0.0048 16.2 0.7 2.2 7.4 0.0 2.4 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase MCRA PF06100.11 OAP65476.1 - 0.036 12.8 0.6 0.051 12.4 0.6 1.1 1 0 0 1 1 1 0 MCRA family Pyr_redox PF00070.27 OAP65476.1 - 0.079 13.5 0.1 0.26 11.9 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 OAP65476.1 - 0.12 11.7 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain MFS_1 PF07690.16 OAP65477.1 - 4.1e-28 98.3 25.2 8.7e-28 97.2 18.7 2.6 1 1 2 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAP65477.1 - 7.9e-08 31.6 4.6 7.9e-08 31.6 4.6 3.5 4 0 0 4 4 4 2 Sugar (and other) transporter Kelch_1 PF01344.25 OAP65478.1 - 0.004 16.7 1.6 1.6 8.4 0.0 3.6 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.15 OAP65478.1 - 0.0053 16.7 0.2 0.078 13.0 0.0 3.0 4 0 0 4 4 4 1 Kelch motif Kelch_6 PF13964.6 OAP65478.1 - 0.04 14.2 1.4 18 5.8 0.0 3.7 4 0 0 4 4 4 0 Kelch motif Kelch_3 PF13415.6 OAP65478.1 - 0.11 12.8 0.7 0.53 10.6 0.1 2.5 2 0 0 2 2 2 0 Galactose oxidase, central domain Kelch_5 PF13854.6 OAP65478.1 - 4.7 7.3 0.0 4.7 7.3 0.0 3.8 4 1 0 4 4 4 0 Kelch motif Kelch_5 PF13854.6 OAP65479.1 - 8.7e-11 41.6 1.6 1.8e-09 37.4 0.7 2.5 2 0 0 2 2 2 1 Kelch motif Syndecan PF01034.20 OAP65479.1 - 0.0067 16.3 0.4 0.012 15.5 0.4 1.3 1 0 0 1 1 1 1 Syndecan domain MGC-24 PF05283.11 OAP65479.1 - 0.04 14.4 0.0 0.04 14.4 0.0 1.6 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Herpes_gE PF02480.16 OAP65479.1 - 0.048 12.4 0.1 0.069 11.9 0.1 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E EphA2_TM PF14575.6 OAP65479.1 - 0.05 14.5 0.0 0.077 13.9 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Kelch_4 PF13418.6 OAP65479.1 - 0.18 11.8 4.1 0.29 11.2 0.9 2.6 2 0 0 2 2 2 0 Galactose oxidase, central domain Shisa PF13908.6 OAP65479.1 - 0.68 10.1 6.4 0.077 13.2 1.4 1.9 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator Cpn60_TCP1 PF00118.24 OAP65481.1 - 1e-155 519.1 4.5 1.2e-155 519.0 4.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Rep_fac_C PF08542.11 OAP65481.1 - 0.034 14.6 0.0 2.5 8.5 0.0 2.9 2 0 0 2 2 2 0 Replication factor C C-terminal domain Peptidase_C14 PF00656.22 OAP65482.1 - 6.7e-62 209.7 0.0 8e-62 209.4 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.6 OAP65482.1 - 0.21 11.5 0.4 0.84 9.6 0.0 2.2 3 0 0 3 3 3 0 Raptor N-terminal CASPase like domain F-box-like PF12937.7 OAP65483.1 - 0.00041 20.2 1.5 0.00097 19.0 1.5 1.6 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 OAP65483.1 - 0.011 16.2 10.1 1.5 9.4 0.0 5.9 6 1 1 7 7 7 0 Leucine Rich repeats (2 copies) NUFIP1 PF10453.9 OAP65483.1 - 0.13 12.1 0.2 0.27 11.1 0.2 1.4 1 0 0 1 1 1 0 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) LRR_1 PF00560.33 OAP65483.1 - 0.2 12.3 0.5 15 6.6 0.1 4.0 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_6 PF13516.6 OAP65483.1 - 0.99 9.6 9.1 0.53 10.5 0.1 4.0 5 0 0 5 5 5 0 Leucine Rich repeat F-box PF00646.33 OAP65483.1 - 1.8 8.5 4.9 1.6 8.7 0.8 2.7 3 0 0 3 3 3 0 F-box domain Med3 PF11593.8 OAP65483.1 - 2.8 7.0 11.8 5.3 6.1 11.8 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Folliculin PF11704.8 OAP65484.1 - 3.9e-48 163.8 0.0 9.6e-48 162.5 0.0 1.7 1 0 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport CLP1_P PF16575.5 OAP65485.1 - 2.7e-10 40.3 0.0 5.8e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop tRNA_anti_2 PF13742.6 OAP65485.1 - 0.11 12.8 0.0 0.56 10.4 0.0 2.1 2 0 0 2 2 2 0 OB-fold nucleic acid binding domain RNA_polI_A34 PF08208.11 OAP65486.1 - 2.2e-30 106.3 5.2 2.2e-30 106.3 5.2 3.3 2 1 2 4 4 4 1 DNA-directed RNA polymerase I subunit RPA34.5 SHMT PF00464.19 OAP65487.1 - 3.8e-209 694.2 0.0 4.4e-209 694.0 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.21 OAP65487.1 - 3.8e-07 29.6 0.0 9.8e-07 28.3 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class I and II Baculo_DNA_bind PF04786.12 OAP65487.1 - 0.053 12.9 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 ssDNA binding protein Beta_elim_lyase PF01212.21 OAP65487.1 - 0.076 12.3 0.0 0.14 11.4 0.0 1.5 1 1 0 1 1 1 0 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 OAP65487.1 - 0.11 11.7 0.1 0.24 10.7 0.1 1.6 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 OAP65487.1 - 0.13 10.8 0.0 0.21 10.1 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Med9 PF07544.13 OAP65488.1 - 1.4e-12 47.6 0.4 1.2e-11 44.5 0.0 2.3 2 0 0 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 SPX PF03105.19 OAP65488.1 - 0.0043 17.0 7.8 0.0049 16.8 7.8 1.2 1 0 0 1 1 1 1 SPX domain Presenilin PF01080.17 OAP65488.1 - 0.026 13.3 4.5 0.033 13.0 4.5 1.2 1 0 0 1 1 1 0 Presenilin Apt1 PF10351.9 OAP65488.1 - 0.035 13.0 1.9 0.043 12.7 1.9 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 OAP65488.1 - 0.059 11.9 0.7 0.08 11.5 0.7 1.2 1 0 0 1 1 1 0 Macoilin family Spc42p PF11544.8 OAP65488.1 - 0.11 12.6 0.0 0.11 12.6 0.0 2.4 2 0 0 2 2 2 0 Spindle pole body component Spc42p Neur_chan_memb PF02932.16 OAP65488.1 - 0.2 11.7 2.7 0.28 11.2 2.7 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region TGF_beta_GS PF08515.12 OAP65488.1 - 0.24 10.9 2.5 0.65 9.5 2.5 1.7 1 0 0 1 1 1 0 Transforming growth factor beta type I GS-motif DUF1843 PF08898.10 OAP65488.1 - 0.26 11.8 0.2 0.26 11.8 0.2 1.7 2 0 0 2 2 1 0 Domain of unknown function (DUF1843) PAT1 PF09770.9 OAP65488.1 - 0.27 9.4 15.9 0.32 9.2 15.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SOG2 PF10428.9 OAP65488.1 - 0.38 9.9 19.1 0.46 9.6 19.1 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein SARAF PF06682.12 OAP65488.1 - 0.53 9.9 8.7 0.95 9.0 8.7 1.4 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Zip PF02535.22 OAP65488.1 - 0.53 9.4 2.6 0.57 9.3 2.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Suf PF05843.14 OAP65488.1 - 0.61 10.0 13.1 0.88 9.5 13.1 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Menin PF05053.13 OAP65488.1 - 0.75 8.1 3.8 0.99 7.7 3.8 1.1 1 0 0 1 1 1 0 Menin Ndc1_Nup PF09531.10 OAP65488.1 - 1.3 7.7 12.0 1.4 7.5 12.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Hid1 PF12722.7 OAP65488.1 - 1.4 7.0 6.5 1.6 6.7 6.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein FAM222A PF15258.6 OAP65488.1 - 1.6 7.8 28.5 2.2 7.3 28.5 1.1 1 0 0 1 1 1 0 Protein family of FAM222A Lin-8 PF03353.15 OAP65488.1 - 2 7.9 9.0 3.2 7.2 9.0 1.4 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist EthD PF07110.11 OAP65489.1 - 1.4e-21 77.4 0.1 1.8e-21 77.1 0.1 1.1 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 OAP65489.1 - 0.0099 16.3 0.0 0.022 15.2 0.0 1.5 1 1 0 1 1 1 1 Methylmuconolactone methyl-isomerase DUF2586 PF10758.9 OAP65489.1 - 0.061 12.5 0.1 0.079 12.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2586) LANC_like PF05147.13 OAP65490.1 - 6.8e-28 97.2 0.0 2.1e-27 95.6 0.0 1.8 1 1 0 1 1 1 1 Lanthionine synthetase C-like protein Lipocalin_5 PF13924.6 OAP65491.1 - 1.7e-25 89.5 0.0 1.9e-25 89.3 0.0 1.0 1 0 0 1 1 1 1 Lipocalin-like domain adh_short PF00106.25 OAP65492.1 - 1.2e-28 100.0 0.0 3.1e-28 98.6 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP65492.1 - 1.6e-23 83.5 0.0 2.6e-23 82.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase HET PF06985.11 OAP65493.1 - 8.5e-25 87.8 0.5 2.1e-24 86.5 0.5 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) NUDIX PF00293.28 OAP65494.1 - 3.5e-09 36.8 0.1 9e-09 35.5 0.1 1.7 1 0 0 1 1 1 1 NUDIX domain Collagen PF01391.18 OAP65494.1 - 5e-07 29.4 25.0 8.7e-07 28.6 25.0 1.2 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) BUD22 PF09073.10 OAP65494.1 - 0.00053 19.4 41.4 0.00072 19.0 41.4 1.2 1 0 0 1 1 1 1 BUD22 Red1 PF07964.11 OAP65494.1 - 0.0069 14.7 15.5 0.0084 14.4 15.5 1.1 1 0 0 1 1 1 1 Rec10 / Red1 FAM60A PF15396.6 OAP65494.1 - 0.29 11.1 13.1 0.45 10.5 13.1 1.3 1 0 0 1 1 1 0 Protein Family FAM60A AAA_11 PF13086.6 OAP65494.1 - 1.6 8.5 12.0 2.3 8.0 12.0 1.4 1 0 0 1 1 1 0 AAA domain NPR3 PF03666.13 OAP65494.1 - 1.8 7.2 22.9 2.9 6.6 22.9 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SLC12 PF03522.15 OAP65494.1 - 6.3 5.7 14.0 9 5.2 14.0 1.2 1 0 0 1 1 1 0 Solute carrier family 12 ATP_transf PF09830.9 OAP65495.1 - 3e-20 72.1 1.1 6.8e-20 71.0 1.1 1.6 2 0 0 2 2 2 1 ATP adenylyltransferase SIR2_2 PF13289.6 OAP65496.1 - 3.9e-05 23.8 0.0 0.00017 21.7 0.0 2.1 1 1 0 1 1 1 1 SIR2-like domain Zn_clus PF00172.18 OAP65497.1 - 1.9e-05 24.7 6.5 3e-05 24.0 6.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UcrQ PF02939.16 OAP65498.1 - 2e-33 114.1 0.2 2.3e-33 113.9 0.2 1.0 1 0 0 1 1 1 1 UcrQ family SF3b1 PF08920.10 OAP65499.1 - 1.2e-30 106.4 9.6 6.5e-30 104.1 5.5 3.1 1 1 1 2 2 2 1 Splicing factor 3B subunit 1 HEAT_EZ PF13513.6 OAP65499.1 - 1.8e-12 47.5 2.0 0.012 16.1 0.0 7.5 7 1 1 8 8 8 2 HEAT-like repeat HEAT_2 PF13646.6 OAP65499.1 - 5.2e-11 42.8 10.3 0.21 12.0 0.1 8.4 4 3 4 10 10 10 4 HEAT repeats HEAT PF02985.22 OAP65499.1 - 4.6e-09 35.8 9.2 0.087 13.1 0.3 8.7 8 0 0 8 8 8 2 HEAT repeat Cnd1 PF12717.7 OAP65499.1 - 2.3e-07 31.0 2.6 0.18 11.9 0.0 6.1 5 2 2 7 7 6 1 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 OAP65499.1 - 3.6e-06 27.5 0.2 2 9.0 0.0 5.5 5 0 0 5 5 5 1 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 OAP65499.1 - 3.7e-06 25.8 1.0 0.0039 15.8 0.1 3.3 3 1 0 3 3 3 2 Adaptin N terminal region NUC173 PF08161.12 OAP65499.1 - 0.0001 22.1 0.4 1.1 8.9 0.0 4.4 4 1 1 5 5 5 2 NUC173 domain DUF3385 PF11865.8 OAP65499.1 - 0.00012 22.0 1.3 0.023 14.6 0.0 4.7 5 1 1 6 6 6 1 Domain of unknown function (DUF3385) UNC45-central PF11701.8 OAP65499.1 - 0.00033 20.6 0.0 0.0011 18.9 0.0 1.9 1 0 0 1 1 1 1 Myosin-binding striated muscle assembly central CLASP_N PF12348.8 OAP65499.1 - 0.0024 17.5 0.5 0.9 9.1 0.0 3.6 4 0 0 4 4 4 1 CLASP N terminal DRIM PF07539.12 OAP65499.1 - 0.036 12.4 0.6 6.2 5.0 0.0 3.8 2 1 1 3 3 3 0 Down-regulated in metastasis MMS19_C PF12460.8 OAP65499.1 - 0.097 11.8 0.0 7.1 5.6 0.0 3.3 3 1 1 4 4 4 0 RNAPII transcription regulator C-terminal MTP18 PF10558.9 OAP65499.1 - 0.2 11.6 0.3 1.2 9.1 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial 18 KDa protein (MTP18) RasGAP PF00616.19 OAP65500.1 - 5.3e-32 111.2 0.0 1.2e-20 74.2 0.0 2.5 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase PPR_2 PF13041.6 OAP65501.1 - 0.015 15.5 0.0 0.028 14.6 0.0 1.4 1 0 0 1 1 1 0 PPR repeat family PCRF PF03462.18 OAP65502.1 - 2.7e-50 170.9 0.0 7.4e-50 169.5 0.0 1.8 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 OAP65502.1 - 8.2e-34 116.0 3.3 1.7e-33 115.0 3.3 1.5 1 0 0 1 1 1 1 RF-1 domain zf-CCCH PF00642.24 OAP65502.1 - 1e-11 44.4 10.7 4.8e-06 26.4 2.1 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 OAP65502.1 - 2e-10 40.2 10.2 2e-06 27.4 2.3 2.3 2 0 0 2 2 2 2 CCCH-type zinc finger Torus PF16131.5 OAP65502.1 - 2.7e-09 37.7 4.9 0.00077 20.1 0.3 2.6 1 1 1 2 2 2 2 Torus domain zf_CCCH_4 PF18345.1 OAP65502.1 - 1e-08 34.9 18.8 0.00013 21.9 4.2 2.4 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_3 PF15663.5 OAP65502.1 - 0.00015 21.9 1.9 0.00031 20.9 1.9 1.4 1 0 0 1 1 1 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 OAP65502.1 - 0.048 14.2 14.7 0.61 10.7 3.1 2.5 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger eIF3_N PF09440.10 OAP65503.1 - 1e-42 145.7 4.3 1e-42 145.7 4.3 1.9 2 0 0 2 2 2 1 eIF3 subunit 6 N terminal domain PCI PF01399.27 OAP65503.1 - 3.1e-13 50.1 0.0 1.1e-12 48.3 0.0 2.0 1 0 0 1 1 1 1 PCI domain Herpes_UL6 PF01763.16 OAP65503.1 - 0.013 14.1 0.5 0.024 13.2 0.5 1.4 1 0 0 1 1 1 0 Herpesvirus UL6 like DUF148 PF02520.17 OAP65503.1 - 0.37 10.9 6.7 0.93 9.6 1.4 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF148 Img2 PF05046.14 OAP65504.1 - 9.3e-24 83.5 0.1 1.4e-23 83.0 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) ARID PF01388.21 OAP65505.1 - 7.6e-20 71.4 0.0 1.9e-19 70.1 0.0 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain AAA PF00004.29 OAP65506.1 - 4e-45 153.5 0.6 1.4e-44 151.7 0.0 2.1 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 OAP65506.1 - 3.2e-10 39.8 0.1 2.1e-09 37.2 0.0 2.2 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 OAP65506.1 - 7.8e-09 35.7 0.1 2.8e-08 33.9 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 OAP65506.1 - 6.2e-08 32.9 0.0 1.3e-07 31.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 OAP65506.1 - 1.9e-07 31.7 0.5 3.7e-05 24.2 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain DUF815 PF05673.13 OAP65506.1 - 4.3e-06 26.1 0.0 7.9e-06 25.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 OAP65506.1 - 4e-05 23.9 1.3 0.0081 16.4 0.1 2.6 1 1 0 2 2 2 1 AAA domain AAA_7 PF12775.7 OAP65506.1 - 0.00015 21.3 0.0 0.0078 15.7 0.1 2.8 2 1 0 2 2 2 1 P-loop containing dynein motor region RuvB_N PF05496.12 OAP65506.1 - 0.00038 20.2 0.0 0.0011 18.7 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_lid_3 PF17862.1 OAP65506.1 - 0.00044 20.0 0.1 0.00099 18.9 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_18 PF13238.6 OAP65506.1 - 0.00085 19.9 0.0 0.0026 18.3 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_28 PF13521.6 OAP65506.1 - 0.00094 19.5 0.0 0.002 18.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 OAP65506.1 - 0.0012 19.2 0.0 0.0031 17.9 0.0 1.7 1 0 0 1 1 1 1 RNA helicase TIP49 PF06068.13 OAP65506.1 - 0.0012 18.1 0.0 0.0024 17.1 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain TsaE PF02367.17 OAP65506.1 - 0.0015 18.5 0.0 0.024 14.6 0.0 2.2 1 1 1 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 OAP65506.1 - 0.0023 18.0 0.0 0.0087 16.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 OAP65506.1 - 0.0026 17.7 0.0 0.012 15.5 0.0 2.0 2 0 0 2 2 2 1 NTPase AAA_30 PF13604.6 OAP65506.1 - 0.0057 16.4 0.1 0.014 15.2 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_3 PF07726.11 OAP65506.1 - 0.0067 16.3 0.0 0.02 14.8 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 OAP65506.1 - 0.0069 16.3 0.5 0.11 12.4 0.0 2.8 4 0 0 4 4 2 1 NACHT domain Mg_chelatase PF01078.21 OAP65506.1 - 0.0083 15.5 0.0 0.019 14.3 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 OAP65506.1 - 0.0093 16.1 0.0 0.02 15.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain TniB PF05621.11 OAP65506.1 - 0.011 15.2 0.0 0.55 9.6 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein IstB_IS21 PF01695.17 OAP65506.1 - 0.012 15.3 0.1 0.043 13.5 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_24 PF13479.6 OAP65506.1 - 0.022 14.5 0.2 0.051 13.3 0.2 1.7 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 OAP65506.1 - 0.043 13.7 1.1 0.23 11.4 0.1 2.5 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea ATPase PF06745.13 OAP65506.1 - 0.05 12.9 1.1 0.56 9.5 0.0 2.4 3 0 0 3 3 2 0 KaiC AAA_11 PF13086.6 OAP65506.1 - 0.055 13.3 0.1 0.14 11.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain Bac_DnaA PF00308.18 OAP65506.1 - 0.071 12.9 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein Sigma54_activat PF00158.26 OAP65506.1 - 0.084 12.6 0.2 1.4 8.6 0.0 2.5 2 1 0 2 2 2 0 Sigma-54 interaction domain Viral_Hsp90 PF03225.14 OAP65506.1 - 0.13 10.8 0.0 0.2 10.1 0.0 1.2 1 0 0 1 1 1 0 Viral heat shock protein Hsp90 homologue AAA_19 PF13245.6 OAP65506.1 - 0.13 12.6 0.1 0.41 11.0 0.1 1.8 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 OAP65506.1 - 0.14 11.8 1.8 0.26 10.9 0.1 2.1 2 1 1 3 3 3 0 AAA domain AAA_29 PF13555.6 OAP65506.1 - 0.18 11.6 0.0 0.35 10.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Parvo_NS1 PF01057.17 OAP65506.1 - 0.21 10.7 0.0 0.39 9.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Aft1_HRA PF11786.8 OAP65507.1 - 4.6e-25 87.8 7.2 4.6e-25 87.8 7.2 3.2 2 0 0 2 2 2 1 Aft1 HRA domain Aft1_OSA PF11785.8 OAP65507.1 - 6e-16 58.6 10.5 6e-16 58.6 10.5 3.1 2 1 1 3 3 3 1 Aft1 osmotic stress response (OSM) domain Aft1_HRR PF11787.8 OAP65507.1 - 4.6e-15 56.5 7.7 4.6e-15 56.5 7.7 4.7 3 3 0 3 3 3 1 Aft1 HRR domain bZIP_1 PF00170.21 OAP65507.1 - 1.2e-11 44.5 6.4 2.1e-11 43.7 6.4 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 OAP65507.1 - 2.2e-06 27.6 5.4 4.3e-06 26.7 5.4 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 OAP65507.1 - 0.0018 18.8 4.4 0.0045 17.5 4.4 1.6 1 0 0 1 1 1 1 bZIP Maf transcription factor CDO_I PF05995.12 OAP65507.1 - 0.021 14.1 0.0 0.043 13.1 0.0 1.4 1 0 0 1 1 1 0 Cysteine dioxygenase type I DivIC PF04977.15 OAP65507.1 - 0.21 11.4 1.1 0.41 10.5 1.1 1.4 1 0 0 1 1 1 0 Septum formation initiator Ank_2 PF12796.7 OAP65508.1 - 1.7e-11 44.5 1.7 8.1e-06 26.3 0.0 3.8 3 0 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAP65508.1 - 1.7e-11 44.4 1.9 0.0071 16.9 0.0 6.3 3 2 3 6 6 6 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OAP65508.1 - 0.27 11.6 3.2 12 6.4 0.0 4.6 6 0 0 6 6 6 0 Ankyrin repeats (many copies) Pyridoxal_deC PF00282.19 OAP65509.1 - 2.1e-74 250.5 0.0 1.2e-63 215.1 0.0 2.7 3 0 0 3 3 3 2 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 OAP65509.1 - 0.0002 20.7 0.0 0.00043 19.6 0.0 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 OAP65509.1 - 0.0017 17.4 0.0 0.0024 16.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V PUF PF00806.19 OAP65510.1 - 6.8e-11 41.2 0.0 0.16 11.7 0.0 7.4 9 0 0 9 9 9 4 Pumilio-family RNA binding repeat Prefoldin_2 PF01920.20 OAP65511.1 - 1.2e-20 73.4 11.6 1.4e-20 73.2 11.6 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_3 PF13758.6 OAP65511.1 - 0.0048 16.9 4.5 0.006 16.6 4.5 1.3 1 0 0 1 1 1 1 Prefoldin subunit Fib_alpha PF08702.10 OAP65511.1 - 0.024 14.8 9.2 0.12 12.6 9.2 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DHR10 PF18595.1 OAP65511.1 - 0.04 14.0 16.8 0.23 11.5 5.5 2.1 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain NPV_P10 PF05531.12 OAP65511.1 - 0.053 14.0 8.8 0.12 12.8 1.8 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein CREPT PF16566.5 OAP65511.1 - 0.14 12.3 7.3 0.16 12.1 0.9 2.1 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour Tropomyosin_1 PF12718.7 OAP65511.1 - 0.14 12.3 13.4 0.88 9.7 4.9 2.1 2 0 0 2 2 2 0 Tropomyosin like DUF641 PF04859.12 OAP65511.1 - 0.18 12.2 8.4 1.2 9.5 0.8 2.1 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) Prefoldin PF02996.17 OAP65511.1 - 0.27 11.2 10.8 0.3 11.0 0.8 2.1 2 0 0 2 2 2 0 Prefoldin subunit Spc7 PF08317.11 OAP65511.1 - 0.71 8.7 14.2 1.7 7.4 14.2 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein End3 PF12761.7 OAP65511.1 - 0.71 10.0 9.5 0.98 9.6 9.5 1.1 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 DUF4201 PF13870.6 OAP65511.1 - 0.78 9.4 12.1 2.5 7.8 3.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) YabA PF06156.13 OAP65511.1 - 0.83 10.3 7.8 3.8 8.2 1.0 2.1 2 0 0 2 2 2 0 Initiation control protein YabA DUF1664 PF07889.12 OAP65511.1 - 1.1 9.3 8.6 3.1 7.8 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Apt1 PF10351.9 OAP65511.1 - 1.4 7.7 5.7 1.7 7.4 5.7 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain TMPIT PF07851.13 OAP65511.1 - 1.6 7.9 7.2 0.58 9.4 1.0 2.0 1 1 1 2 2 2 0 TMPIT-like protein DUF4407 PF14362.6 OAP65511.1 - 3.3 7.0 11.4 7.4 5.8 9.6 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) GAS PF13851.6 OAP65511.1 - 6.5 6.1 15.7 72 2.6 15.7 2.0 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding RF-1 PF00472.20 OAP65511.1 - 8.7 6.3 11.0 1.3 9.0 2.9 2.1 2 0 0 2 2 2 0 RF-1 domain AAA PF00004.29 OAP65512.1 - 6.2e-42 143.2 0.0 1e-41 142.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 OAP65512.1 - 8.1e-31 105.8 0.1 3.6e-30 103.8 0.1 2.2 3 0 0 3 3 2 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 OAP65512.1 - 1.5e-21 76.2 3.2 3.5e-21 75.0 3.2 1.7 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 OAP65512.1 - 5.8e-06 26.0 0.0 2.7e-05 23.9 0.0 2.1 2 0 0 2 2 2 1 AAA+ lid domain RuvB_N PF05496.12 OAP65512.1 - 1.1e-05 25.2 0.0 2.1e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 OAP65512.1 - 1.4e-05 25.5 0.0 0.00016 22.1 0.0 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 OAP65512.1 - 2.8e-05 24.1 0.0 0.00012 22.0 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 OAP65512.1 - 3.2e-05 23.3 0.0 5.4e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain RNA_helicase PF00910.22 OAP65512.1 - 6.2e-05 23.3 0.0 0.011 16.1 0.0 2.6 2 0 0 2 2 2 1 RNA helicase IstB_IS21 PF01695.17 OAP65512.1 - 8.8e-05 22.3 0.0 0.00018 21.3 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.6 OAP65512.1 - 0.00011 22.5 0.1 0.019 15.2 0.0 2.6 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.6 OAP65512.1 - 0.00037 20.5 0.0 0.0007 19.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 OAP65512.1 - 0.00049 19.3 0.0 0.0014 17.9 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 OAP65512.1 - 0.00054 20.5 0.0 0.002 18.7 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.14 OAP65512.1 - 0.0007 19.8 0.0 0.0082 16.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 OAP65512.1 - 0.0017 18.5 0.0 0.004 17.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 OAP65512.1 - 0.0031 17.2 0.0 0.011 15.4 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_17 PF13207.6 OAP65512.1 - 0.0036 17.7 0.1 0.037 14.4 0.0 2.6 3 0 0 3 3 2 1 AAA domain AAA_25 PF13481.6 OAP65512.1 - 0.0042 16.7 0.4 0.49 10.0 0.1 3.1 1 1 2 3 3 3 1 AAA domain AAA_7 PF12775.7 OAP65512.1 - 0.014 14.9 0.1 0.075 12.5 0.0 2.2 2 1 0 2 2 2 0 P-loop containing dynein motor region Torsin PF06309.11 OAP65512.1 - 0.018 15.1 0.0 0.085 13.0 0.0 1.9 2 0 0 2 2 2 0 Torsin Mg_chelatase PF01078.21 OAP65512.1 - 0.027 13.9 0.0 0.081 12.3 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Parvo_NS1 PF01057.17 OAP65512.1 - 0.044 12.9 0.0 0.096 11.8 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ATPase PF06745.13 OAP65512.1 - 0.048 13.0 0.1 7.1 5.9 0.0 3.0 2 1 1 3 3 3 0 KaiC ATPase_2 PF01637.18 OAP65512.1 - 0.066 13.1 0.1 1.4 8.8 0.0 2.3 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea CPT PF07931.12 OAP65512.1 - 0.078 12.8 0.0 0.52 10.1 0.0 2.0 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein PhoH PF02562.16 OAP65512.1 - 0.084 12.3 0.1 0.16 11.4 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.12 OAP65512.1 - 0.088 12.7 0.0 0.67 9.8 0.0 2.1 1 1 1 2 2 2 0 NACHT domain Use1 PF09753.9 OAP65512.1 - 0.13 12.0 0.2 0.23 11.1 0.2 1.3 1 0 0 1 1 1 0 Membrane fusion protein Use1 AFG1_ATPase PF03969.16 OAP65512.1 - 0.13 11.1 0.0 0.4 9.5 0.0 1.8 2 0 0 2 2 2 0 AFG1-like ATPase Cytidylate_kin PF02224.18 OAP65512.1 - 0.14 11.8 1.1 0.51 10.0 0.0 2.4 2 1 0 2 2 2 0 Cytidylate kinase Zeta_toxin PF06414.12 OAP65512.1 - 0.28 10.4 1.7 1.5 8.0 0.1 2.8 2 1 1 3 3 3 0 Zeta toxin XFP_N PF09364.10 OAP65513.1 - 1.2e-168 560.6 0.0 1.6e-168 560.2 0.0 1.2 1 0 0 1 1 1 1 XFP N-terminal domain XFP_C PF09363.10 OAP65513.1 - 1.3e-84 282.8 0.0 1.8e-84 282.3 0.0 1.2 1 0 0 1 1 1 1 XFP C-terminal domain XFP PF03894.15 OAP65513.1 - 9e-81 269.8 0.0 1.3e-80 269.2 0.0 1.2 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase COesterase PF00135.28 OAP65515.1 - 7.8e-70 236.2 0.0 1.1e-69 235.8 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAP65515.1 - 1.4e-07 31.6 0.2 1.5e-06 28.3 0.3 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold ELYS PF13934.6 OAP65516.1 - 1.3e-55 188.8 0.8 1.5e-55 188.6 0.8 1.1 1 0 0 1 1 1 1 Nuclear pore complex assembly DUF4404 PF14357.6 OAP65516.1 - 0.17 12.5 0.0 0.33 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) Epimerase PF01370.21 OAP65517.1 - 0.067 12.6 0.0 0.093 12.2 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family p450 PF00067.22 OAP65520.1 - 7.1e-63 213.0 0.0 9.6e-63 212.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Smim3 PF17307.2 OAP65520.1 - 0.032 13.7 0.4 0.071 12.6 0.4 1.5 1 0 0 1 1 1 0 Small integral membrane protein 3 FMO-like PF00743.19 OAP65521.1 - 5.3e-16 58.1 0.1 4.2e-15 55.2 0.0 2.1 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OAP65521.1 - 5e-10 39.5 0.0 1.3e-09 38.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAP65521.1 - 6.1e-09 35.5 0.0 1.6e-07 30.8 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAP65521.1 - 9.6e-07 28.3 0.0 2.9e-05 23.4 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 OAP65521.1 - 1e-05 25.0 0.0 8.5e-05 21.9 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAP65521.1 - 1.3e-05 25.3 0.0 0.0019 18.2 0.0 3.1 2 1 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.17 OAP65521.1 - 0.011 14.9 0.0 0.065 12.5 0.0 1.9 2 0 0 2 2 2 0 Thi4 family DAO PF01266.24 OAP65521.1 - 0.014 15.0 0.0 0.33 10.5 0.0 2.6 2 1 1 3 3 3 0 FAD dependent oxidoreductase NAD_binding_4 PF07993.12 OAP65522.1 - 5.5e-44 150.3 0.0 8.4e-44 149.7 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 OAP65522.1 - 6.5e-30 104.1 0.0 1.1e-29 103.3 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 OAP65522.1 - 2.5e-10 40.2 0.0 1.2e-09 38.1 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 OAP65522.1 - 6.5e-09 36.0 0.0 1.6e-08 34.7 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.19 OAP65522.1 - 0.0075 15.3 0.0 0.023 13.7 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 OAP65522.1 - 0.012 15.0 0.0 0.11 11.9 0.0 2.0 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase Semialdhyde_dh PF01118.24 OAP65522.1 - 0.022 15.2 0.0 0.052 14.0 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.10 OAP65522.1 - 0.05 13.5 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 KR domain Polysacc_synt_2 PF02719.15 OAP65522.1 - 0.059 12.5 0.0 0.3 10.2 0.0 2.1 3 0 0 3 3 3 0 Polysaccharide biosynthesis protein DXP_reductoisom PF02670.16 OAP65522.1 - 0.17 12.6 0.0 0.38 11.5 0.0 1.6 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Fungal_trans PF04082.18 OAP65523.1 - 9e-25 87.2 0.5 1.6e-24 86.4 0.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP65523.1 - 0.0038 17.3 9.5 0.0074 16.4 9.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cwf_Cwc_15 PF04889.12 OAP65523.1 - 7.4 6.2 6.6 15 5.2 2.3 2.4 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein HET PF06985.11 OAP65524.1 - 3.7e-33 114.9 0.2 6.9e-33 114.1 0.2 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) TRP PF06011.12 OAP65525.1 - 3.7e-164 546.5 33.7 4.4e-164 546.2 33.7 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 OAP65525.1 - 5.4e-40 137.0 0.4 8.9e-40 136.3 0.4 1.4 1 0 0 1 1 1 1 ML-like domain zf-PHD-like PF15446.6 OAP65526.1 - 3.5e-67 225.2 11.4 9.1e-67 223.9 11.4 1.8 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain SNF2_N PF00176.23 OAP65526.1 - 7.4e-50 169.6 0.1 1.7e-49 168.4 0.1 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-CCCH_6 PF18585.1 OAP65526.1 - 2e-25 88.4 0.1 7.3e-25 86.6 0.1 2.1 1 0 0 1 1 1 1 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 Helicase_C PF00271.31 OAP65526.1 - 9e-19 67.9 0.0 3e-18 66.2 0.0 1.9 2 0 0 2 2 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAP65526.1 - 1.2e-06 28.7 0.0 3.5e-06 27.1 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 OAP65526.1 - 6e-06 25.6 1.1 1.6e-05 24.2 1.1 1.6 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 PHD PF00628.29 OAP65526.1 - 5.1e-05 23.1 1.8 5.1e-05 23.1 1.8 3.9 4 2 0 4 4 2 1 PHD-finger DUF1087 PF06465.13 OAP65526.1 - 0.00035 20.6 0.6 0.0016 18.4 0.6 2.2 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1087) Chromo PF00385.24 OAP65526.1 - 0.00049 20.0 1.1 0.8 9.7 0.6 3.0 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain AAA_7 PF12775.7 OAP65526.1 - 0.023 14.2 0.0 0.075 12.5 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region SnAC PF14619.6 OAP65526.1 - 0.025 15.2 0.6 0.025 15.2 0.6 3.3 3 0 0 3 3 1 0 Snf2-ATP coupling, chromatin remodelling complex FANCL_C PF11793.8 OAP65526.1 - 0.15 12.2 2.0 0.44 10.8 2.0 1.8 1 0 0 1 1 1 0 FANCL C-terminal domain SpoU_methylase PF00588.19 OAP65527.1 - 3.8e-23 82.2 0.0 6.3e-23 81.5 0.0 1.4 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 OAP65527.1 - 0.00079 19.7 0.0 0.011 16.0 0.0 2.4 1 1 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding Ammonium_transp PF00909.21 OAP65529.1 - 2.7e-66 223.9 27.1 4.5e-34 117.8 10.5 2.4 2 1 0 2 2 2 2 Ammonium Transporter Family Patatin PF01734.22 OAP65530.1 - 1.7e-24 87.1 1.1 6.2e-24 85.3 1.1 2.0 1 0 0 1 1 1 1 Patatin-like phospholipase RsgA_GTPase PF03193.16 OAP65530.1 - 0.004 17.1 0.1 0.0098 15.8 0.1 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 OAP65530.1 - 0.0042 17.5 2.1 0.14 12.5 1.4 3.3 2 1 0 2 2 2 1 AAA ATPase domain ABC_tran PF00005.27 OAP65530.1 - 0.0063 17.0 0.0 0.015 15.8 0.0 1.6 1 0 0 1 1 1 1 ABC transporter zf-C3HC4 PF00097.25 OAP65530.1 - 0.0088 15.9 5.0 0.025 14.4 5.0 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) AAA_21 PF13304.6 OAP65530.1 - 0.023 14.5 0.0 0.056 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 OAP65530.1 - 0.024 14.7 0.1 0.05 13.7 0.1 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_29 PF13555.6 OAP65530.1 - 0.03 14.1 1.6 0.038 13.7 0.1 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain SMC_N PF02463.19 OAP65530.1 - 0.043 13.2 0.0 0.087 12.3 0.0 1.4 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_33 PF13671.6 OAP65530.1 - 0.14 12.3 0.0 0.43 10.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain DHODB_Fe-S_bind PF10418.9 OAP65530.1 - 0.21 11.4 1.1 0.69 9.8 0.1 2.3 2 0 0 2 2 2 0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B AAA_15 PF13175.6 OAP65530.1 - 0.23 11.2 0.0 0.44 10.2 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain zf-C3HC4_4 PF15227.6 OAP65530.1 - 0.27 11.4 5.9 1.1 9.4 5.9 2.2 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 OAP65530.1 - 0.3 11.1 4.0 0.88 9.6 4.0 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.6 OAP65530.1 - 0.36 10.8 5.0 1.2 9.1 5.0 2.0 1 0 0 1 1 1 0 zinc-RING finger domain Fig1 PF12351.8 OAP65531.1 - 8e-59 198.7 6.3 8e-59 198.7 6.3 2.0 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.12 OAP65531.1 - 2.1e-07 30.8 8.7 3.1e-07 30.3 8.7 1.2 1 0 0 1 1 1 1 SUR7/PalI family DUF898 PF05987.13 OAP65531.1 - 0.08 12.0 13.0 0.21 10.6 13.0 1.7 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF898) DUF2207 PF09972.9 OAP65531.1 - 6.1 5.5 16.7 5.3 5.7 3.7 2.5 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) XPG_N PF00752.17 OAP65532.1 - 7.7e-23 80.9 0.0 1.8e-22 79.7 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 OAP65532.1 - 8.9e-22 77.3 0.0 2.1e-21 76.1 0.0 1.7 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.7 OAP65532.1 - 0.00017 21.2 0.0 0.00036 20.1 0.0 1.5 1 0 0 1 1 1 1 XPG domain containing 5_3_exonuc PF01367.20 OAP65532.1 - 0.11 13.1 0.0 0.47 11.1 0.0 2.0 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold Tma16 PF11176.8 OAP65533.1 - 3.4e-46 156.7 3.9 4.1e-46 156.5 3.9 1.1 1 0 0 1 1 1 1 Translation machinery-associated protein 16 MAM33 PF02330.16 OAP65534.1 - 4.9e-62 209.6 0.6 7.1e-62 209.1 0.6 1.2 1 0 0 1 1 1 1 Mitochondrial glycoprotein p450 PF00067.22 OAP65535.1 - 2.7e-54 184.7 0.0 7.7e-54 183.2 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 Bacteriocin_IIc PF10439.9 OAP65537.1 - 0.078 13.1 1.0 0.078 13.1 1.0 1.7 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide DUF4006 PF13179.6 OAP65537.1 - 1.6 8.7 5.9 46 4.0 5.9 2.3 1 1 0 1 1 1 0 Family of unknown function (DUF4006) Dala_Dala_lig_C PF07478.13 OAP65538.1 - 1.3e-08 34.6 0.0 2e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 OAP65538.1 - 0.0015 18.6 0.0 0.0027 17.8 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_TupA PF14305.6 OAP65538.1 - 0.0036 17.1 0.0 0.0067 16.2 0.0 1.4 1 0 0 1 1 1 1 TupA-like ATPgrasp ATP-grasp_4 PF13535.6 OAP65538.1 - 0.0044 16.6 0.0 0.013 15.1 0.0 1.8 1 1 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 OAP65538.1 - 0.023 14.2 0.0 0.043 13.3 0.0 1.6 1 1 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain FA_desaturase PF00487.24 OAP65539.1 - 2.2e-25 89.9 27.8 3.3e-25 89.4 27.8 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 OAP65539.1 - 6.7e-08 32.6 0.0 1.2e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FhuF PF06276.12 OAP65539.1 - 2 8.8 5.5 3.1 8.2 1.3 2.4 2 0 0 2 2 2 0 Ferric iron reductase FhuF-like transporter Rad51 PF08423.11 OAP65540.1 - 3.6e-10 39.5 0.0 6.2e-09 35.5 0.0 2.1 1 1 0 1 1 1 1 Rad51 AAA_25 PF13481.6 OAP65540.1 - 1e-05 25.2 0.1 3.5e-05 23.5 0.0 2.0 2 1 0 2 2 2 1 AAA domain PSY3 PF16836.5 OAP65540.1 - 0.0068 15.9 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 Shu complex component Psy3, DNA-binding description Dynamin_N PF00350.23 OAP65540.1 - 0.11 12.5 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Dynamin family Mitochondr_Som1 PF11093.8 OAP65541.1 - 5.6e-23 80.7 0.1 7.6e-23 80.3 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial export protein Som1 TAF8_C PF10406.9 OAP65542.1 - 8.5e-14 51.8 0.1 2.5e-13 50.3 0.1 1.8 1 0 0 1 1 1 1 Transcription factor TFIID complex subunit 8 C-term RNA_pol_Rpb1_2 PF00623.20 OAP65543.1 - 4.3e-74 248.3 0.1 9.3e-74 247.2 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_5 PF04998.17 OAP65543.1 - 8.1e-74 248.4 0.0 1.3e-73 247.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.12 OAP65543.1 - 3.4e-67 227.0 0.0 6e-67 226.2 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_3 PF04983.18 OAP65543.1 - 4.2e-37 127.5 0.0 1.2e-36 126.1 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 OAP65543.1 - 1.8e-25 89.0 0.0 5.8e-25 87.3 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 HORMA PF02301.18 OAP65544.1 - 1.8e-33 115.9 0.1 2.1e-33 115.7 0.1 1.0 1 0 0 1 1 1 1 HORMA domain DUF3530 PF12048.8 OAP65544.1 - 0.019 14.4 0.3 0.032 13.6 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) GTP_EFTU PF00009.27 OAP65545.1 - 2e-49 167.8 0.0 3.9e-49 166.8 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 OAP65545.1 - 3e-42 143.1 4.8 4.9e-42 142.4 4.8 1.3 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 OAP65545.1 - 1.5e-21 76.2 0.0 2.9e-21 75.3 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 OAP65545.1 - 5.6e-06 26.6 0.0 1.3e-05 25.5 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 OAP65545.1 - 2.7e-05 24.2 0.0 7.5e-05 22.8 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 OAP65545.1 - 6.3e-05 22.6 0.0 0.00022 20.9 0.0 1.8 2 0 0 2 2 2 1 Ras family EFG_II PF14492.6 OAP65545.1 - 0.0019 18.3 0.0 0.0055 16.8 0.0 1.8 1 1 0 1 1 1 1 Elongation Factor G, domain II SRPRB PF09439.10 OAP65545.1 - 0.0075 15.7 0.0 0.016 14.7 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RF3_C PF16658.5 OAP65545.1 - 0.012 15.5 0.0 0.028 14.2 0.0 1.6 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain Roc PF08477.13 OAP65545.1 - 0.097 12.9 0.0 0.89 9.8 0.0 2.5 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1_Xtn PF16897.5 OAP65545.1 - 0.13 12.3 0.0 0.3 11.1 0.0 1.6 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Snurportin1 PF11538.8 OAP65545.1 - 0.39 10.9 2.1 1.1 9.5 2.1 1.7 1 0 0 1 1 1 0 Snurportin1 LapA_dom PF06305.11 OAP65546.1 - 0.78 9.6 0.0 0.78 9.6 0.0 3.1 4 0 0 4 4 4 0 Lipopolysaccharide assembly protein A domain SMC_N PF02463.19 OAP65547.1 - 6.1e-78 261.2 0.0 1.3e-77 260.2 0.0 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 OAP65547.1 - 1.5e-24 86.6 0.0 5.2e-24 84.8 0.0 2.1 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 OAP65547.1 - 7.3e-12 45.7 6.5 1.5e-05 25.0 0.2 3.9 3 2 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 OAP65547.1 - 3.3e-08 34.3 14.7 3.3e-08 34.3 14.7 6.7 2 2 2 4 4 1 1 AAA domain HrpB7 PF09486.10 OAP65547.1 - 5.9e-05 23.5 13.8 5.9e-05 23.5 13.8 7.1 4 2 2 6 6 6 2 Bacterial type III secretion protein (HrpB7) AAA_29 PF13555.6 OAP65547.1 - 0.00026 20.7 0.0 0.00058 19.5 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain UPF0242 PF06785.11 OAP65547.1 - 0.003 17.7 8.4 0.003 17.7 8.4 6.9 3 2 4 7 7 7 2 Uncharacterised protein family (UPF0242) N-terminus DUF1664 PF07889.12 OAP65547.1 - 0.047 13.7 61.2 2.1 8.4 6.5 7.7 5 1 1 7 7 7 0 Protein of unknown function (DUF1664) SbcCD_C PF13558.6 OAP65547.1 - 0.075 13.3 0.0 0.94 9.8 0.0 2.6 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit ABC_tran PF00005.27 OAP65547.1 - 0.4 11.2 0.0 0.4 11.2 0.0 6.2 4 2 0 5 5 4 0 ABC transporter EzrA PF06160.12 OAP65547.1 - 0.42 8.7 87.5 1.1 7.4 37.8 5.7 3 2 2 5 5 5 0 Septation ring formation regulator, EzrA Cob_adeno_trans PF01923.18 OAP65547.1 - 1.9 8.6 38.1 0.44 10.7 2.7 6.0 3 1 2 5 5 5 0 Cobalamin adenosyltransferase Fungal_trans_2 PF11951.8 OAP65548.1 - 0.023 13.5 1.6 1.6 7.5 0.3 2.2 2 0 0 2 2 2 0 Fungal specific transcription factor domain DUF3196 PF11428.8 OAP65548.1 - 0.16 11.4 0.1 0.25 10.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3196) MFS_1 PF07690.16 OAP65549.1 - 8.2e-37 126.9 30.9 1.2e-36 126.4 30.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAP65549.1 - 2.7e-14 52.9 26.7 3.9e-14 52.4 26.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Trp_oprn_chp PF09534.10 OAP65549.1 - 0.01 15.6 0.0 0.056 13.2 0.0 2.0 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Phage_holin_3_3 PF16083.5 OAP65549.1 - 0.15 12.2 16.0 0.35 11.0 0.6 4.4 4 0 0 4 4 4 0 LydA holin phage, holin superfamily III UNC-93 PF05978.16 OAP65549.1 - 7.3 6.3 16.7 0.04 13.6 4.4 2.9 2 1 1 3 3 3 0 Ion channel regulatory protein UNC-93 ADH_zinc_N PF00107.26 OAP65550.1 - 6.9e-23 81.0 0.1 1.2e-22 80.3 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAP65550.1 - 1.6e-15 58.3 0.0 3.3e-15 57.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAP65550.1 - 1.3e-07 31.4 0.0 2.5e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 OAP65550.1 - 0.071 13.0 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase PEP_mutase PF13714.6 OAP65551.1 - 8.7e-45 153.0 0.3 1e-44 152.8 0.3 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 OAP65551.1 - 2.2e-16 59.5 0.4 3.1e-16 59.0 0.4 1.1 1 0 0 1 1 1 1 Isocitrate lyase family Pantoate_transf PF02548.15 OAP65551.1 - 0.034 13.5 0.0 0.056 12.8 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate hydroxymethyltransferase 6PGD PF00393.19 OAP65551.1 - 0.056 12.8 0.0 0.085 12.2 0.0 1.1 1 0 0 1 1 1 0 6-phosphogluconate dehydrogenase, C-terminal domain Coronavirus_5 PF05528.11 OAP65551.1 - 0.14 12.1 0.0 1.1 9.3 0.0 2.3 3 0 0 3 3 3 0 Coronavirus gene 5 protein DIOX_N PF14226.6 OAP65553.1 - 4.2e-18 66.2 0.0 8.6e-18 65.2 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OAP65553.1 - 3e-12 46.9 0.0 5.6e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF4473 PF14747.6 OAP65553.1 - 0.068 13.7 0.5 12 6.5 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4473) MmgE_PrpD PF03972.14 OAP65554.1 - 4.4e-36 124.4 0.0 5e-36 124.2 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family NSs PF11073.8 OAP65555.1 - 0.13 11.7 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Rift valley fever virus non structural protein (NSs) like NMT1 PF09084.11 OAP65556.1 - 1.4e-07 31.7 0.1 2.4e-07 31.0 0.1 1.4 1 1 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 OAP65556.1 - 0.0013 18.5 0.2 0.076 12.7 0.0 2.4 3 0 0 3 3 3 1 NMT1-like family OpuAC PF04069.12 OAP65556.1 - 0.045 13.3 1.0 0.053 13.1 0.1 1.6 2 0 0 2 2 2 0 Substrate binding domain of ABC-type glycine betaine transport system HTH_DeoR PF08220.12 OAP65556.1 - 0.19 11.5 0.0 6.1 6.7 0.0 2.6 3 0 0 3 3 3 0 DeoR-like helix-turn-helix domain Cortexin PF11057.8 OAP65557.1 - 0.081 12.8 0.3 0.081 12.8 0.3 2.1 2 0 0 2 2 2 0 Cortexin of kidney adh_short_C2 PF13561.6 OAP65558.1 - 4.2e-50 170.5 0.0 5.4e-50 170.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP65558.1 - 1.5e-41 142.0 0.1 1.8e-41 141.8 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAP65558.1 - 2.9e-07 30.6 0.1 2.9e-06 27.3 0.1 2.2 1 1 1 2 2 2 1 KR domain Pyr_redox_3 PF13738.6 OAP65559.1 - 1.5e-13 50.7 0.0 4.6e-11 42.5 0.0 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 OAP65559.1 - 2e-10 39.8 0.0 1.3e-09 37.1 0.0 2.2 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 OAP65559.1 - 2.6e-10 40.0 0.0 1.7e-06 27.5 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAP65559.1 - 1.9e-08 34.4 0.2 9.7e-08 32.1 0.1 2.4 1 1 1 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 OAP65559.1 - 2e-06 27.2 0.0 3.3e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAP65559.1 - 5.6e-05 22.9 0.7 0.0023 17.6 0.2 2.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 OAP65559.1 - 0.00027 20.2 0.7 0.0058 15.8 0.0 2.8 3 1 0 4 4 4 1 L-lysine 6-monooxygenase (NADPH-requiring) Shikimate_DH PF01488.20 OAP65559.1 - 0.00076 19.5 0.0 0.053 13.6 0.0 3.0 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 OAP65559.1 - 0.0009 18.6 0.2 0.0032 16.8 0.3 1.9 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.6 OAP65559.1 - 0.02 14.9 0.2 0.25 11.3 0.1 2.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding HI0933_like PF03486.14 OAP65559.1 - 0.034 12.9 0.3 0.057 12.1 0.3 1.3 1 0 0 1 1 1 0 HI0933-like protein FAD_oxidored PF12831.7 OAP65559.1 - 0.037 13.4 0.7 0.19 11.0 0.2 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.17 OAP65559.1 - 0.085 12.1 0.0 0.19 11.0 0.0 1.5 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.12 OAP65559.1 - 0.095 11.7 0.2 0.68 8.9 0.2 2.5 2 1 0 2 2 2 0 Lycopene cyclase protein 2-Hacid_dh_C PF02826.19 OAP65559.1 - 0.097 12.0 0.0 0.31 10.4 0.0 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GIDA PF01134.22 OAP65559.1 - 0.18 10.9 0.0 3 6.8 0.1 2.4 3 0 0 3 3 3 0 Glucose inhibited division protein A Sugar_tr PF00083.24 OAP65560.1 - 1e-78 265.2 27.8 1.2e-78 265.0 27.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP65560.1 - 2.2e-30 105.8 60.8 9.9e-24 83.9 35.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2070 PF09843.9 OAP65560.1 - 0.59 8.4 9.9 1 7.6 9.9 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) TssO PF17561.2 OAP65560.1 - 1.6 8.8 5.3 14 5.8 0.7 2.3 2 0 0 2 2 2 0 Type VI secretion system, TssO Pyr_redox_2 PF07992.14 OAP65561.1 - 3.1e-07 29.9 0.0 0.00048 19.5 0.0 3.3 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAP65561.1 - 1.7e-06 28.2 0.2 7.6e-06 26.1 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.20 OAP65561.1 - 0.00014 21.9 0.0 0.0086 16.1 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase FMO-like PF00743.19 OAP65561.1 - 0.0002 20.0 0.0 0.00059 18.4 0.0 1.8 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_9 PF13454.6 OAP65561.1 - 0.00065 19.7 0.2 0.2 11.6 0.0 3.6 4 0 0 4 4 4 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 OAP65561.1 - 0.0011 18.3 0.2 0.012 14.9 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAP65561.1 - 0.013 14.7 0.0 0.16 11.0 0.0 2.5 3 0 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) AOX PF01786.17 OAP65562.1 - 5.9e-93 310.4 0.1 6.8e-93 310.2 0.1 1.0 1 0 0 1 1 1 1 Alternative oxidase 2OG-FeII_Oxy PF03171.20 OAP65563.1 - 4.1e-19 68.9 0.0 9.5e-19 67.8 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 OAP65563.1 - 1.1e-17 64.8 0.0 1.7e-17 64.2 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Glyoxalase_2 PF12681.7 OAP65563.1 - 0.14 12.1 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 Glyoxalase-like domain Sugar_tr PF00083.24 OAP65564.1 - 9.9e-93 311.4 13.5 2.8e-92 309.9 13.5 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP65564.1 - 8.8e-34 117.0 32.6 2.6e-25 89.1 10.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 OAP65564.1 - 1.1e-06 28.2 3.9 1.1e-06 28.2 3.9 2.7 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 OAP65564.1 - 0.074 11.3 4.5 0.92 7.7 0.0 2.7 1 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Pkinase PF00069.25 OAP65565.1 - 1.2e-73 247.8 0.0 1.6e-73 247.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP65565.1 - 1.8e-39 135.6 0.0 2.7e-39 135.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase AdenylateSensor PF16579.5 OAP65565.1 - 1.5e-17 64.1 0.1 1.9e-06 28.3 0.1 3.5 3 0 0 3 3 3 3 Adenylate sensor of SNF1-like protein kinase UBA_2 PF08587.11 OAP65565.1 - 8.1e-17 61.1 0.1 4.1e-16 58.8 0.1 2.2 2 0 0 2 2 2 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.6 OAP65565.1 - 7.6e-07 28.7 0.0 1.3e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 OAP65565.1 - 0.00087 18.9 0.2 0.0016 18.1 0.2 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 OAP65565.1 - 0.0063 15.9 0.1 0.013 14.9 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OAP65565.1 - 0.0082 15.1 0.2 0.014 14.3 0.2 1.4 1 0 0 1 1 1 1 Haspin like kinase domain YukC PF10140.9 OAP65565.1 - 0.012 14.4 0.2 0.019 13.9 0.2 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC APH PF01636.23 OAP65565.1 - 0.046 13.6 0.3 0.52 10.2 0.1 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF3455 PF11937.8 OAP65566.1 - 3.8e-09 37.1 0.1 2.8e-08 34.3 0.1 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF3455) PRELI PF04707.14 OAP65567.1 - 1.1e-24 87.1 0.0 4.2e-21 75.4 0.0 2.2 2 0 0 2 2 2 2 PRELI-like family tRNA-synt_1b PF00579.25 OAP65568.1 - 2.3e-22 79.7 0.0 4.9e-22 78.6 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetases class I (W and Y) Antimicrobial_1 PF08018.11 OAP65568.1 - 0.045 13.9 0.1 0.045 13.9 0.1 2.3 3 0 0 3 3 3 0 Frog antimicrobial peptide Aminotran_4 PF01063.19 OAP65569.1 - 1.4e-24 87.3 0.0 2.1e-23 83.4 0.0 2.1 1 1 0 1 1 1 1 Amino-transferase class IV Acetyltransf_1 PF00583.25 OAP65570.1 - 9.1e-07 29.1 0.0 1.4e-06 28.5 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OAP65570.1 - 2.1e-05 24.9 0.0 4.8e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 OAP65570.1 - 0.00014 22.0 0.0 0.0096 16.0 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OAP65570.1 - 0.0011 18.9 0.0 0.0019 18.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 OAP65570.1 - 0.13 12.4 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase PhoLip_ATPase_C PF16212.5 OAP65571.1 - 0.37 10.5 6.3 0.03 14.1 1.1 1.7 2 0 0 2 2 2 0 Phospholipid-translocating P-type ATPase C-terminal AA_permease_2 PF13520.6 OAP65572.1 - 4.2e-50 170.8 43.8 5.3e-50 170.5 43.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAP65572.1 - 2.6e-22 79.1 36.3 3.5e-22 78.6 36.3 1.1 1 0 0 1 1 1 1 Amino acid permease Shikimate_dh_N PF08501.11 OAP65573.1 - 3.3e-12 46.5 0.0 7.2e-12 45.4 0.0 1.6 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.20 OAP65573.1 - 4.2e-07 30.1 0.0 7.8e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ThiF PF00899.21 OAP65573.1 - 0.074 12.4 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 ThiF family TrkA_N PF02254.18 OAP65573.1 - 0.097 12.9 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain YoaP PF14268.6 OAP65573.1 - 0.14 11.7 0.1 0.27 10.8 0.1 1.4 1 0 0 1 1 1 0 YoaP-like DUF4261 PF14080.6 OAP65573.1 - 0.16 12.1 0.0 3 8.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4261) AP_endonuc_2 PF01261.24 OAP65574.1 - 1.5e-28 99.6 0.1 2.2e-28 99.1 0.1 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel TPR_1 PF00515.28 OAP65575.1 - 2.2e-43 144.4 38.7 2.9e-06 26.8 0.1 11.6 10 1 1 11 11 11 10 Tetratricopeptide repeat TPR_2 PF07719.17 OAP65575.1 - 5.2e-39 129.2 35.7 3.1e-05 23.8 0.1 11.8 10 1 1 11 11 11 10 Tetratricopeptide repeat TPR_11 PF13414.6 OAP65575.1 - 3.6e-23 81.0 29.8 4.3e-07 29.5 0.6 8.7 5 2 3 8 8 8 7 TPR repeat TPR_8 PF13181.6 OAP65575.1 - 6.9e-23 78.9 38.7 0.0037 17.4 0.1 12.1 12 0 0 12 12 12 6 Tetratricopeptide repeat TPR_16 PF13432.6 OAP65575.1 - 7.2e-22 77.8 19.2 5.4e-06 26.9 0.2 7.1 5 1 1 7 7 7 6 Tetratricopeptide repeat TPR_17 PF13431.6 OAP65575.1 - 2.7e-20 71.2 15.4 0.0068 16.7 0.0 9.2 9 0 0 9 9 8 5 Tetratricopeptide repeat TPR_12 PF13424.6 OAP65575.1 - 1.3e-18 67.0 28.2 0.00013 22.1 0.2 8.1 6 3 1 7 7 7 5 Tetratricopeptide repeat TPR_7 PF13176.6 OAP65575.1 - 3e-16 58.2 22.1 0.018 15.0 0.1 9.6 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_19 PF14559.6 OAP65575.1 - 1.3e-15 57.7 25.8 4.4e-05 23.9 1.0 7.7 4 3 3 7 7 7 5 Tetratricopeptide repeat TPR_9 PF13371.6 OAP65575.1 - 6.2e-15 55.1 13.1 3.6e-05 23.8 0.4 6.2 3 1 4 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.6 OAP65575.1 - 2e-11 43.7 24.1 0.076 13.9 0.2 9.7 3 3 8 11 11 10 3 Tetratricopeptide repeat ANAPC3 PF12895.7 OAP65575.1 - 1.7e-09 37.7 17.8 0.019 15.2 0.5 5.6 3 1 2 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 OAP65575.1 - 9.5e-06 25.3 27.9 0.14 12.1 0.2 9.2 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_MalT PF17874.1 OAP65575.1 - 3.6e-05 23.3 8.1 0.00016 21.2 3.7 2.6 1 1 1 2 2 2 1 MalT-like TPR region SHNi-TPR PF10516.9 OAP65575.1 - 8.3e-05 22.0 12.3 3 7.4 0.1 6.8 7 0 0 7 7 7 2 SHNi-TPR MAS20 PF02064.15 OAP65575.1 - 0.0011 19.1 7.5 0.054 13.6 1.0 4.2 4 0 0 4 4 4 1 MAS20 protein import receptor AP3D1 PF06375.11 OAP65575.1 - 0.03 14.5 1.5 0.071 13.3 1.5 1.6 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 Sel1 PF08238.12 OAP65575.1 - 0.05 14.3 9.2 0.84 10.4 0.0 4.7 5 0 0 5 5 3 0 Sel1 repeat TPR_6 PF13174.6 OAP65575.1 - 0.091 13.4 32.1 5.8 7.8 0.5 9.3 10 0 0 10 10 8 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 OAP65575.1 - 0.092 13.2 1.0 28 5.2 0.1 3.5 3 1 0 3 3 3 0 Alkyl sulfatase dimerisation HemY_N PF07219.13 OAP65575.1 - 0.29 11.4 15.0 3.9 7.7 0.0 5.7 4 1 2 6 6 6 0 HemY protein N-terminus NARP1 PF12569.8 OAP65575.1 - 0.36 9.7 26.9 0.075 11.9 0.2 4.8 2 2 2 5 5 5 0 NMDA receptor-regulated protein 1 TPR_20 PF14561.6 OAP65575.1 - 0.36 11.2 9.3 0.57 10.6 0.3 4.4 5 0 0 5 5 4 0 Tetratricopeptide repeat MIT PF04212.18 OAP65575.1 - 0.82 9.8 20.7 26 5.0 0.3 6.8 6 0 0 6 6 6 0 MIT (microtubule interacting and transport) domain FHA PF00498.26 OAP65576.1 - 7.8e-13 48.6 0.0 1.4e-12 47.7 0.0 1.5 1 0 0 1 1 1 1 FHA domain 2OG-FeII_Oxy_2 PF13532.6 OAP65577.1 - 7.7e-28 98.0 1.5 8.2e-28 97.9 0.1 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Isochorismatase PF00857.20 OAP65577.1 - 3e-24 86.1 0.0 5.6e-23 82.0 0.0 2.4 1 1 0 1 1 1 1 Isochorismatase family Acyl-CoA_dh_1 PF00441.24 OAP65578.1 - 1.7e-23 83.5 1.0 2.9e-23 82.7 1.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 OAP65578.1 - 6.3e-16 59.0 0.2 1.4e-15 57.9 0.2 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 OAP65578.1 - 9e-06 25.8 0.0 2.8e-05 24.2 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 OAP65578.1 - 0.00067 19.9 1.6 0.00072 19.8 0.3 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Glyco_hydro_76 PF03663.14 OAP65579.1 - 4e-127 424.7 17.7 4.9e-127 424.4 17.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 OAP65579.1 - 0.02 14.0 7.0 0.057 12.5 0.4 2.8 3 0 0 3 3 3 0 Glycosyl Hydrolase Family 88 Fungal_trans_2 PF11951.8 OAP65580.1 - 5.6e-07 28.7 0.6 0.00068 18.5 0.0 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain His_Phos_1 PF00300.22 OAP65581.1 - 1e-09 38.4 0.8 3.6e-09 36.6 0.1 2.1 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) Piezo_RRas_bdg PF12166.8 OAP65584.1 - 0.035 13.4 0.2 0.044 13.1 0.2 1.2 1 0 0 1 1 1 0 Piezo non-specific cation channel, R-Ras-binding domain Abhydrolase_1 PF00561.20 OAP65587.1 - 2e-16 60.4 0.0 3.5e-16 59.6 0.0 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAP65587.1 - 5.8e-15 55.2 0.0 1.4e-14 53.9 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OAP65587.1 - 2.6e-12 47.9 0.7 3e-12 47.6 0.7 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 OAP65587.1 - 5.5e-07 29.3 0.3 0.0001 21.9 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family DLH PF01738.18 OAP65587.1 - 2.9e-05 23.7 0.0 0.0017 18.0 0.0 2.3 2 0 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S15 PF02129.18 OAP65587.1 - 0.00026 20.7 0.1 0.0007 19.3 0.1 1.7 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) FSH1 PF03959.13 OAP65587.1 - 0.00074 19.2 0.0 0.0042 16.8 0.0 2.0 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_4 PF08386.10 OAP65587.1 - 0.0036 17.4 0.0 0.017 15.2 0.0 2.1 2 1 1 3 3 3 1 TAP-like protein BAAT_C PF08840.11 OAP65587.1 - 0.015 15.3 0.0 0.026 14.4 0.0 1.5 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal PGAP1 PF07819.13 OAP65587.1 - 0.017 14.9 0.0 0.07 12.8 0.0 1.9 2 0 0 2 2 2 0 PGAP1-like protein PhoPQ_related PF10142.9 OAP65587.1 - 0.031 12.9 0.0 0.048 12.3 0.0 1.2 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein Abhydrolase_5 PF12695.7 OAP65587.1 - 0.036 13.8 0.4 0.31 10.8 0.0 2.3 3 0 0 3 3 3 0 Alpha/beta hydrolase family Thioesterase PF00975.20 OAP65587.1 - 0.046 13.8 0.1 0.089 12.9 0.1 1.6 1 1 0 1 1 1 0 Thioesterase domain DUF915 PF06028.11 OAP65587.1 - 0.17 11.2 0.0 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) MBF1 PF08523.10 OAP65589.1 - 1.8e-26 92.4 0.7 3.6e-26 91.4 0.7 1.5 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 OAP65589.1 - 1.4e-05 25.1 0.0 2.3e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 OAP65589.1 - 0.0037 17.6 0.0 0.0086 16.4 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain Iso_dh PF00180.20 OAP65590.1 - 6.6e-75 252.4 0.0 7.7e-75 252.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase SH3_1 PF00018.28 OAP65591.1 - 1.3e-15 56.7 0.0 2.9e-15 55.6 0.0 1.6 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 OAP65591.1 - 3.7e-13 49.1 0.0 7.3e-13 48.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 OAP65591.1 - 5.3e-10 38.8 0.0 8.9e-10 38.1 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain MRP-S28 PF10213.9 OAP65593.1 - 3.7e-47 159.9 0.1 6.4e-47 159.1 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein Glyco_tran_28_C PF04101.16 OAP65594.1 - 8.1e-15 55.2 0.0 1.1e-10 41.8 0.1 2.0 2 0 0 2 2 2 2 Glycosyltransferase family 28 C-terminal domain UDPGT PF00201.18 OAP65594.1 - 0.027 13.3 0.1 0.034 13.0 0.1 1.1 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase ECH_1 PF00378.20 OAP65594.1 - 0.073 12.4 0.0 0.091 12.0 0.0 1.2 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase RR_TM4-6 PF06459.12 OAP65596.1 - 0.035 13.9 5.3 0.046 13.5 5.3 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RNA_pol_Rpc4 PF05132.14 OAP65596.1 - 0.063 13.7 1.7 0.077 13.4 1.7 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 Presenilin PF01080.17 OAP65596.1 - 0.14 10.8 8.9 0.17 10.6 8.9 1.1 1 0 0 1 1 1 0 Presenilin Pet20 PF08692.10 OAP65596.1 - 0.21 12.3 1.1 0.45 11.2 0.9 1.6 1 1 0 1 1 1 0 Mitochondrial protein Pet20 DUF913 PF06025.12 OAP65596.1 - 0.33 9.9 1.4 0.43 9.5 1.4 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Borrelia_P83 PF05262.11 OAP65596.1 - 0.41 9.1 10.5 0.46 8.9 10.5 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein CDC45 PF02724.14 OAP65596.1 - 0.68 8.2 15.6 0.88 7.8 15.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Sec62 PF03839.16 OAP65596.1 - 0.85 9.1 5.4 1.1 8.7 5.4 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 DUF5094 PF17015.5 OAP65596.1 - 2.7 8.1 8.3 3.4 7.7 8.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5094) Rrn6 PF10214.9 OAP65596.1 - 3.4 6.0 10.5 4.2 5.7 10.5 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor NPR3 PF03666.13 OAP65596.1 - 5.1 5.8 10.3 6.1 5.5 10.3 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Pex14_N PF04695.13 OAP65596.1 - 5.4 7.7 10.0 6.4 7.4 9.0 1.4 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Hid1 PF12722.7 OAP65596.1 - 5.5 5.0 5.7 6 4.9 5.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Neur_chan_memb PF02932.16 OAP65596.1 - 9.4 6.2 5.1 13 5.8 5.1 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region zf-U1 PF06220.12 OAP65597.1 - 2.9e-06 26.9 1.0 3.9e-06 26.5 1.0 1.2 1 0 0 1 1 1 1 U1 zinc finger Actin PF00022.19 OAP65598.1 - 4.8e-126 420.7 0.0 2.2e-125 418.5 0.0 1.8 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 OAP65598.1 - 0.029 13.2 0.0 0.42 9.4 0.0 2.3 1 1 0 1 1 1 0 MreB/Mbl protein DUF3602 PF12223.8 OAP65599.1 - 6.5e-23 81.1 11.2 3.2e-18 66.1 0.5 3.1 2 1 1 3 3 3 2 Protein of unknown function (DUF3602) Adap_comp_sub PF00928.21 OAP65600.1 - 8.7e-59 199.0 0.0 1.1e-58 198.7 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 OAP65600.1 - 0.00054 19.9 0.0 0.0008 19.3 0.0 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF4188 PF13826.6 OAP65601.1 - 3.1e-30 104.9 0.2 4.5e-30 104.4 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4188) ABM PF03992.16 OAP65601.1 - 0.00054 20.0 0.3 0.00091 19.3 0.3 1.3 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Dehydratase_hem PF13816.6 OAP65601.1 - 0.0062 16.0 0.6 0.024 14.1 0.3 1.6 1 1 1 2 2 2 2 Haem-containing dehydratase DUF4267 PF14087.6 OAP65602.1 - 0.00066 19.7 3.2 0.0036 17.4 3.2 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4267) SNF2_N PF00176.23 OAP65603.1 - 1.2e-74 251.1 0.1 2.5e-74 250.1 0.1 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 OAP65603.1 - 7.2e-45 151.7 1.7 7.2e-45 151.7 1.7 2.6 3 0 0 3 3 3 1 SLIDE HAND PF09110.11 OAP65603.1 - 7e-37 126.6 2.9 7e-37 126.6 2.9 3.5 5 0 0 5 5 5 1 HAND Helicase_C PF00271.31 OAP65603.1 - 1.5e-18 67.2 0.9 5.4e-18 65.4 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAP65603.1 - 3.7e-11 43.3 0.0 2.7e-10 40.5 0.0 2.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 OAP65603.1 - 0.00015 21.6 0.0 0.00059 19.7 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 OAP65603.1 - 0.00034 19.9 0.0 0.0013 17.9 0.0 2.0 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 SWI2_SNF2 PF18766.1 OAP65603.1 - 0.00045 20.0 0.3 0.0017 18.0 0.0 2.2 2 0 0 2 2 2 1 SWI2/SNF2 ATPase Myb_DNA-binding PF00249.31 OAP65603.1 - 0.0037 17.4 0.2 4.2 7.7 0.0 3.5 2 1 0 2 2 2 2 Myb-like DNA-binding domain DEAD_2 PF06733.15 OAP65603.1 - 0.029 14.0 0.1 0.068 12.8 0.1 1.5 1 0 0 1 1 1 0 DEAD_2 DUF4588 PF15251.6 OAP65604.1 - 7.5e-09 35.7 2.1 5.2e-08 33.0 2.1 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4588) Menin PF05053.13 OAP65604.1 - 0.36 9.1 2.9 0.46 8.8 2.9 1.1 1 0 0 1 1 1 0 Menin Halogen_Hydrol PF10112.9 OAP65605.1 - 0.12 12.3 0.0 0.15 12.0 0.0 1.1 1 0 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein DUF4536 PF15055.6 OAP65605.1 - 0.81 10.0 11.5 1.2 9.5 0.7 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4536) DAO PF01266.24 OAP65606.1 - 1e-36 127.2 0.0 1.3e-36 127.0 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAP65606.1 - 2.7e-05 24.3 0.0 5.6e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 OAP65606.1 - 7.8e-05 21.9 0.1 0.00094 18.4 0.0 2.5 3 1 0 3 3 3 1 FAD binding domain Glu_dehyd_C PF16912.5 OAP65606.1 - 0.00023 20.7 0.0 0.0016 18.0 0.0 2.0 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus Pyr_redox_2 PF07992.14 OAP65606.1 - 0.00024 20.5 0.0 0.012 14.8 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAP65606.1 - 0.0044 17.0 0.0 0.15 12.0 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 OAP65606.1 - 0.006 15.9 0.0 0.047 13.0 0.0 2.0 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 OAP65606.1 - 0.017 14.4 0.0 0.028 13.7 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Shikimate_DH PF01488.20 OAP65606.1 - 0.026 14.6 0.0 0.047 13.7 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GMC_oxred_N PF00732.19 OAP65606.1 - 0.044 13.1 0.0 0.74 9.1 0.0 2.4 2 1 0 2 2 2 0 GMC oxidoreductase HI0933_like PF03486.14 OAP65606.1 - 0.046 12.4 0.0 0.54 8.9 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.17 OAP65606.1 - 0.049 12.9 0.0 0.09 12.0 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 OAP65606.1 - 0.063 12.5 0.0 0.14 11.4 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 OAP65606.1 - 0.18 11.4 0.1 0.39 10.3 0.0 1.6 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.18 OAP65606.1 - 0.21 11.5 0.0 0.34 10.8 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 OAP65607.1 - 7.4e-53 178.5 0.0 1.1e-52 177.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 OAP65607.1 - 1.2e-16 60.6 0.0 1.5e-16 60.3 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 OAP65607.1 - 0.00047 20.4 0.0 0.0014 18.8 0.0 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase ADH_zinc_N PF00107.26 OAP65608.1 - 1.6e-23 83.1 3.4 1.7e-22 79.8 2.8 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAP65608.1 - 9.2e-22 77.0 0.7 1.9e-21 76.0 0.7 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 OAP65608.1 - 1e-05 26.6 1.4 2e-05 25.7 1.4 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase F_bP_aldolase PF01116.20 OAP65608.1 - 0.0044 16.5 0.6 0.0061 16.1 0.6 1.2 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II adh_short PF00106.25 OAP65608.1 - 0.17 11.3 3.8 0.68 9.4 3.8 2.1 1 1 0 1 1 1 0 short chain dehydrogenase Fungal_trans PF04082.18 OAP65610.1 - 1.4e-22 80.0 0.0 3.6e-22 78.7 0.0 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAP65610.1 - 1e-08 35.2 11.8 1.6e-08 34.5 11.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.24 OAP65611.1 - 3.9e-71 240.2 26.2 3e-70 237.4 19.2 1.9 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 OAP65611.1 - 1.6e-16 60.2 58.2 2.3e-13 49.8 23.4 2.7 2 1 1 3 3 3 2 Major Facilitator Superfamily adh_short_C2 PF13561.6 OAP65612.1 - 4.6e-53 180.2 0.8 5.7e-53 179.9 0.8 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP65612.1 - 1.3e-45 155.3 3.5 1.6e-45 155.0 3.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAP65612.1 - 2.6e-13 50.3 1.5 3.4e-13 49.9 1.5 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAP65612.1 - 7e-06 25.7 0.6 1.3e-05 24.8 0.3 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAP65612.1 - 0.00029 20.3 0.2 0.00039 19.9 0.2 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase THF_DHG_CYH_C PF02882.19 OAP65612.1 - 0.018 14.4 0.1 0.044 13.1 0.1 1.7 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Glyco_transf_5 PF08323.11 OAP65612.1 - 0.055 13.2 0.0 0.25 11.0 0.0 1.8 2 0 0 2 2 2 0 Starch synthase catalytic domain ADH_zinc_N PF00107.26 OAP65613.1 - 2.3e-17 63.2 0.4 8.6e-17 61.3 0.2 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 OAP65613.1 - 7.3e-06 25.6 0.3 0.1 12.1 0.0 2.4 2 1 0 2 2 2 2 Glucose dehydrogenase C-terminus FAD_binding_2 PF00890.24 OAP65613.1 - 1.4e-05 24.4 3.6 1.5e-05 24.3 2.8 1.3 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 OAP65613.1 - 0.00055 19.3 0.2 0.0069 15.7 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAP65613.1 - 0.0017 17.1 2.0 0.0024 16.6 2.0 1.2 1 0 0 1 1 1 1 HI0933-like protein ThiF PF00899.21 OAP65613.1 - 0.0048 16.3 0.6 0.0086 15.5 0.1 1.7 2 0 0 2 2 2 1 ThiF family AlaDh_PNT_C PF01262.21 OAP65613.1 - 0.01 15.2 0.1 0.017 14.5 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 OAP65613.1 - 0.018 14.3 2.0 0.053 12.8 1.0 2.1 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAP65613.1 - 0.039 14.2 2.0 0.089 13.0 2.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain AdoHcyase_NAD PF00670.21 OAP65613.1 - 0.045 13.8 0.2 0.083 13.0 0.2 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Pyr_redox PF00070.27 OAP65613.1 - 0.074 13.6 0.3 0.074 13.6 0.3 2.1 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 OAP65613.1 - 0.08 12.5 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_7 PF13241.6 OAP65613.1 - 0.087 13.3 0.6 0.18 12.2 0.4 1.7 1 1 0 1 1 1 0 Putative NAD(P)-binding DAO PF01266.24 OAP65613.1 - 0.24 11.0 2.3 0.29 10.7 1.1 1.6 1 1 0 2 2 2 0 FAD dependent oxidoreductase adh_short PF00106.25 OAP65614.1 - 2.8e-40 137.9 0.0 3.6e-40 137.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP65614.1 - 1.7e-30 106.3 0.0 2.5e-30 105.8 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP65614.1 - 2.8e-06 27.4 0.0 5.3e-06 26.5 0.0 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 OAP65614.1 - 0.00039 20.0 0.0 0.0011 18.5 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family ABM PF03992.16 OAP65615.1 - 1.4e-06 28.3 0.0 2e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Aldo_ket_red PF00248.21 OAP65616.1 - 9.1e-47 159.7 0.0 1.9e-44 152.1 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Shikimate_dh_N PF08501.11 OAP65617.1 - 8.9e-23 80.4 0.0 1.8e-22 79.4 0.0 1.5 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 OAP65617.1 - 4.6e-06 26.3 0.0 1.3e-05 24.9 0.0 1.8 2 0 0 2 2 2 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 OAP65617.1 - 0.13 12.3 0.0 0.21 11.6 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FMO-like PF00743.19 OAP65618.1 - 7.5e-13 47.7 0.1 7.9e-11 41.1 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OAP65618.1 - 4e-09 36.6 0.0 9e-09 35.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 OAP65618.1 - 9.1e-08 31.6 0.1 0.0015 17.7 0.0 4.0 4 0 0 4 4 4 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 OAP65618.1 - 1.7e-06 27.5 0.0 0.00018 20.9 0.0 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAP65618.1 - 3.2e-06 26.6 0.0 0.031 13.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAP65618.1 - 0.00031 20.7 0.2 0.18 11.8 0.0 3.4 4 0 0 4 4 4 1 FAD-NAD(P)-binding DAO PF01266.24 OAP65618.1 - 0.02 14.5 0.0 0.12 11.9 0.0 2.2 3 0 0 3 3 3 0 FAD dependent oxidoreductase HI0933_like PF03486.14 OAP65618.1 - 0.1 11.3 0.0 0.17 10.5 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Sugar_tr PF00083.24 OAP65620.1 - 5.9e-94 315.5 19.8 6.8e-94 315.3 19.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP65620.1 - 2.2e-25 89.4 52.4 7.6e-21 74.4 23.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily C2 PF00168.30 OAP65621.1 - 5e-17 62.1 0.0 8.3e-17 61.4 0.0 1.4 1 0 0 1 1 1 1 C2 domain GFO_IDH_MocA PF01408.22 OAP65622.1 - 2.5e-17 63.8 0.6 4e-17 63.1 0.6 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 OAP65622.1 - 0.0038 17.2 0.0 0.0078 16.2 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 OAP65622.1 - 0.019 15.6 0.1 0.028 15.0 0.1 1.3 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Polbeta PF18765.1 OAP65622.1 - 0.067 13.3 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase UTP15_C PF09384.10 OAP65623.1 - 7.6e-45 152.2 0.7 1.4e-44 151.3 0.7 1.5 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.32 OAP65623.1 - 7.9e-19 67.7 3.1 6e-05 23.7 0.0 4.8 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAP65623.1 - 3.2e-08 33.7 0.8 0.003 17.8 0.0 4.5 4 2 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Sacchrp_dh_NADP PF03435.18 OAP65623.1 - 0.06 13.6 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain ABA_WDS PF02496.16 OAP65623.1 - 0.11 13.0 0.3 0.3 11.6 0.3 1.6 1 0 0 1 1 1 0 ABA/WDS induced protein Interferon PF00143.19 OAP65623.1 - 0.13 12.4 0.0 0.25 11.5 0.0 1.3 1 0 0 1 1 1 0 Interferon alpha/beta domain Asp PF00026.23 OAP65624.1 - 1.4e-65 221.8 3.2 1.7e-65 221.5 3.2 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OAP65624.1 - 3.3e-09 37.2 4.2 2e-08 34.6 1.6 2.7 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 OAP65624.1 - 1.7e-05 25.4 0.6 0.3 11.8 0.2 3.2 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 OAP65624.1 - 0.15 12.7 0.8 36 5.0 0.0 2.9 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease CAP59_mtransfer PF11735.8 OAP65625.1 - 1e-65 221.8 0.0 1.5e-65 221.2 0.0 1.3 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 HIT PF01230.23 OAP65626.1 - 5e-24 84.9 0.2 7.5e-24 84.3 0.2 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 OAP65626.1 - 9.1e-14 51.9 0.0 1.2e-13 51.5 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 OAP65626.1 - 0.00054 19.8 0.0 0.00072 19.4 0.0 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 IMUP PF15761.5 OAP65627.1 - 0.026 15.2 6.4 0.031 15.0 6.4 1.2 1 0 0 1 1 1 0 Immortalisation up-regulated protein CRAL_TRIO PF00650.20 OAP65628.1 - 2.3e-44 150.9 0.0 6.3e-44 149.5 0.0 1.7 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 OAP65628.1 - 2e-15 56.7 2.9 2.4e-15 56.4 0.2 2.5 3 0 0 3 3 3 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 OAP65628.1 - 3.3e-06 27.3 0.0 6.6e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain NmrA PF05368.13 OAP65630.1 - 9.8e-41 139.8 0.0 1.2e-40 139.6 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAP65630.1 - 3.7e-13 49.8 0.0 5.2e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAP65630.1 - 4.1e-07 29.7 0.0 7.7e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 OAP65630.1 - 1.1e-05 25.7 0.0 2.4e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain 3Beta_HSD PF01073.19 OAP65630.1 - 0.00012 21.2 0.0 0.00015 20.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 OAP65630.1 - 0.0014 18.1 0.0 0.0021 17.5 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase KR PF08659.10 OAP65630.1 - 0.0017 18.3 0.0 0.0024 17.8 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 OAP65630.1 - 0.014 14.9 0.0 0.021 14.3 0.0 1.2 1 0 0 1 1 1 0 short chain dehydrogenase DapB_N PF01113.20 OAP65630.1 - 0.036 14.2 0.0 0.085 13.0 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.24 OAP65630.1 - 0.087 13.3 0.0 0.26 11.7 0.0 1.9 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain GST_N_3 PF13417.6 OAP65631.1 - 2.3e-07 31.1 0.1 5.3e-07 30.0 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OAP65631.1 - 4.5e-05 23.7 0.0 0.00035 20.8 0.0 2.3 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain MAD PF05557.13 OAP65631.1 - 0.0075 14.7 1.4 0.01 14.3 1.4 1.1 1 0 0 1 1 1 1 Mitotic checkpoint protein GST_C_2 PF13410.6 OAP65631.1 - 0.033 14.2 0.0 0.08 13.0 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 OAP65631.1 - 0.037 14.4 0.0 0.084 13.2 0.0 1.7 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain LMWPc PF01451.21 OAP65632.1 - 1.8e-27 96.5 0.0 2e-27 96.3 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Motilin_ghrelin PF04644.12 OAP65632.1 - 0.029 14.1 0.6 0.044 13.6 0.6 1.2 1 0 0 1 1 1 0 Motilin/ghrelin DUF2383 PF09537.10 OAP65632.1 - 0.069 13.5 0.1 0.43 10.9 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF2383) Chitin_synth_1 PF01644.17 OAP65633.1 - 5.6e-75 250.8 0.1 8.6e-75 250.2 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 OAP65633.1 - 6.7e-30 102.9 0.0 1.3e-29 102.0 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 OAP65633.1 - 3.4e-21 75.5 5.0 1.9e-18 66.4 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 OAP65633.1 - 6.2e-08 32.8 6.6 6.2e-08 32.8 6.6 2.8 2 1 0 2 2 2 1 Glycosyl transferase family group 2 TMEM234 PF10639.9 OAP65634.1 - 1.8e-36 124.7 1.4 2.2e-36 124.4 1.4 1.1 1 0 0 1 1 1 1 Putative transmembrane family 234 EamA PF00892.20 OAP65634.1 - 0.0021 18.2 9.0 0.092 12.9 9.0 2.2 1 1 0 1 1 1 1 EamA-like transporter family DUF2985 PF11204.8 OAP65634.1 - 0.095 12.9 2.2 0.8 9.9 0.1 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2985) LSR PF05624.14 OAP65634.1 - 0.9 9.6 0.1 0.9 9.6 0.1 2.7 3 0 0 3 3 3 0 Lipolysis stimulated receptor (LSR) Zn_clus PF00172.18 OAP65635.1 - 9.6e-07 28.8 10.3 9.6e-07 28.8 10.3 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 OAP65635.1 - 6.7e-05 21.9 0.4 0.00011 21.1 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Apt1 PF10351.9 OAP65636.1 - 0.12 11.2 10.8 0.15 10.9 10.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SOG2 PF10428.9 OAP65636.1 - 0.23 10.6 16.1 0.28 10.3 16.1 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Phage_holin_8 PF16931.5 OAP65637.1 - 0.0024 17.8 0.5 0.0041 17.1 0.5 1.3 1 0 0 1 1 1 1 Putative phage holin Syndecan PF01034.20 OAP65637.1 - 0.21 11.5 0.1 0.43 10.5 0.1 1.5 1 0 0 1 1 1 0 Syndecan domain LAT PF15234.6 OAP65637.1 - 0.3 10.8 0.1 0.3 10.8 0.1 2.3 2 1 1 3 3 3 0 Linker for activation of T-cells BTB PF00651.31 OAP65638.1 - 0.031 14.5 0.5 1 9.6 0.0 2.5 3 0 0 3 3 3 0 BTB/POZ domain PhyH PF05721.13 OAP65639.1 - 2.6e-55 187.9 0.0 3.3e-55 187.6 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 OAP65639.1 - 0.096 13.1 0.0 0.2 12.1 0.0 1.5 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase adh_short PF00106.25 OAP65640.1 - 3.6e-28 98.4 0.0 5.1e-28 97.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP65640.1 - 1.5e-22 80.4 0.0 2e-22 79.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP65640.1 - 1e-07 32.1 0.0 1.5e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 KR domain TadZ_N PF16968.5 OAP65640.1 - 0.12 12.1 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Pilus assembly protein TadZ N-terminal NAD_binding_10 PF13460.6 OAP65640.1 - 0.14 12.0 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding MFS_MOT1 PF16983.5 OAP65641.1 - 8.9e-64 212.8 25.5 3.9e-34 117.4 7.8 2.6 2 0 0 2 2 2 2 Molybdate transporter of MFS superfamily Sulfate_transp PF00916.20 OAP65641.1 - 0.00047 19.0 16.9 0.62 8.8 16.8 2.5 1 1 0 1 1 1 1 Sulfate permease family Trp_oprn_chp PF09534.10 OAP65641.1 - 3.4 7.4 7.2 2.6 7.8 0.0 2.9 2 1 1 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) RRM_1 PF00076.22 OAP65642.1 - 3.3e-51 171.0 1.5 1.3e-15 56.9 0.0 4.8 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OAP65642.1 - 4.9e-33 112.8 0.0 5.2e-20 71.1 0.0 4.1 4 0 0 4 4 4 3 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 OAP65642.1 - 2.9e-09 36.8 0.1 0.00097 19.1 0.0 3.5 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 OAP65642.1 - 9.7e-06 25.6 4.4 1.9 8.6 0.0 5.0 5 0 0 5 5 5 2 RNA binding motif PHM7_cyt PF14703.6 OAP65642.1 - 3.5e-05 24.1 11.8 0.75 10.0 0.2 6.0 5 1 0 5 5 5 3 Cytosolic domain of 10TM putative phosphate transporter RRM_5 PF13893.6 OAP65642.1 - 0.00011 21.8 0.0 1.1 8.9 0.0 4.1 2 1 2 4 4 4 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RL PF17797.1 OAP65642.1 - 0.0002 21.2 0.0 0.005 16.7 0.0 2.9 3 0 0 3 3 3 1 RL domain DUF1866 PF08952.11 OAP65642.1 - 0.01 15.7 0.0 5.5 6.8 0.0 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF1866) Lsm_interact PF05391.11 OAP65642.1 - 0.17 11.4 0.2 0.42 10.2 0.2 1.7 1 0 0 1 1 1 0 Lsm interaction motif TPR_14 PF13428.6 OAP65642.1 - 2.1 9.4 11.4 1.6 9.8 0.2 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat Ribosomal_L22 PF00237.19 OAP65643.1 - 1.3e-26 92.8 0.1 8.9e-26 90.1 0.0 2.2 2 0 0 2 2 2 1 Ribosomal protein L22p/L17e p450 PF00067.22 OAP65644.1 - 1e-71 242.1 0.0 2.1e-69 234.5 0.0 2.1 1 1 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.20 OAP65644.1 - 3.3e-27 95.5 0.5 8.7e-26 90.9 0.6 2.8 2 1 0 2 2 2 1 FAD binding domain Flavodoxin_1 PF00258.25 OAP65644.1 - 8.3e-22 77.9 0.0 1.8e-21 76.8 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 OAP65644.1 - 7.3e-11 42.7 0.0 1.6e-10 41.6 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 OAP65644.1 - 0.00037 20.7 0.0 0.00071 19.8 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin domain Peptidase_C39_2 PF13529.6 OAP65644.1 - 0.08 13.5 0.0 0.3 11.6 0.0 1.9 2 0 0 2 2 2 0 Peptidase_C39 like family NrsF PF06532.11 OAP65645.1 - 0.03 14.0 5.8 0.037 13.7 5.8 1.1 1 0 0 1 1 1 0 Negative regulator of sigma F MWFE PF15879.5 OAP65645.1 - 0.19 11.9 0.8 16 5.8 0.0 2.6 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase MWFE subunit FAD_binding_3 PF01494.19 OAP65646.1 - 6.9e-47 160.4 0.0 1e-46 159.8 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAP65646.1 - 4e-07 29.9 1.5 0.0024 17.5 0.0 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAP65646.1 - 5.5e-05 23.3 0.5 0.00013 22.1 0.5 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 OAP65646.1 - 5.7e-05 22.0 0.1 0.00068 18.5 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_9 PF13454.6 OAP65646.1 - 0.00015 21.8 0.3 2.1 8.3 0.0 3.1 3 0 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 OAP65646.1 - 0.00018 20.9 0.2 0.0013 18.0 0.2 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 OAP65646.1 - 0.0012 18.3 1.4 1.2 8.4 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 OAP65646.1 - 0.0013 19.3 0.1 0.29 11.7 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAP65646.1 - 0.0019 17.5 0.3 0.0067 15.7 0.1 1.9 2 0 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.6 OAP65646.1 - 0.0066 15.7 1.1 0.085 12.1 0.8 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 OAP65646.1 - 0.0068 15.7 0.5 0.063 12.6 0.0 2.4 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 OAP65646.1 - 0.0093 15.1 0.2 0.02 13.9 0.2 1.6 1 1 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 OAP65646.1 - 0.019 14.1 1.0 0.045 12.8 1.0 1.6 1 1 1 2 2 2 0 FAD binding domain ODC_AZ PF02100.17 OAP65646.1 - 0.12 12.4 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 Ornithine decarboxylase antizyme SE PF08491.10 OAP65646.1 - 0.19 10.7 0.0 5.1 6.1 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase RVP_2 PF08284.11 OAP65646.1 - 0.2 11.4 0.0 0.38 10.5 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease Trp_halogenase PF04820.14 OAP65646.1 - 0.48 9.2 5.7 3.3 6.4 0.8 2.8 3 0 0 3 3 3 0 Tryptophan halogenase p450 PF00067.22 OAP65647.1 - 1.6e-58 198.6 0.0 2.2e-58 198.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Soyouz_module PF14313.6 OAP65647.1 - 0.13 12.1 0.0 0.29 10.9 0.0 1.6 1 0 0 1 1 1 0 N-terminal region of Paramyxovirinae phosphoprotein (P) Glyco_hydro_30 PF02055.16 OAP65648.1 - 2.1e-10 40.1 0.3 3.3e-10 39.5 0.3 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_30C PF17189.4 OAP65648.1 - 9.3e-09 35.4 0.9 2e-08 34.3 0.9 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain Glyco_hydro_59 PF02057.15 OAP65648.1 - 1.8e-06 27.4 0.0 2.7e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 Glyco_hydr_30_2 PF14587.6 OAP65648.1 - 0.035 13.7 1.4 0.084 12.5 0.0 2.2 2 1 0 2 2 2 0 O-Glycosyl hydrolase family 30 Cu_amine_oxid PF01179.20 OAP65649.1 - 6.6e-162 539.1 0.0 8e-162 538.8 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 OAP65649.1 - 1.1e-05 25.7 0.0 2.6e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 OAP65649.1 - 0.00024 21.3 0.1 0.00049 20.3 0.1 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain AA_permease_2 PF13520.6 OAP65650.1 - 1.3e-62 212.0 47.6 1.6e-62 211.7 47.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAP65650.1 - 3.6e-21 75.3 39.4 5e-21 74.9 39.4 1.1 1 0 0 1 1 1 1 Amino acid permease Sugar_tr PF00083.24 OAP65652.1 - 1.1e-82 278.3 18.1 1.4e-82 278.0 18.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP65652.1 - 4.2e-15 55.5 41.6 3.2e-11 42.7 9.7 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily DUF3659 PF12396.8 OAP65652.1 - 0.15 12.0 0.3 0.32 11.0 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3659) Peptidase_S8 PF00082.22 OAP65653.1 - 2.2e-36 125.7 10.0 4e-36 124.8 9.9 1.3 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 OAP65653.1 - 9.5e-18 64.7 0.5 1.8e-17 63.7 0.1 1.7 2 0 0 2 2 2 1 Peptidase inhibitor I9 GST_N PF02798.20 OAP65655.1 - 4.2e-15 55.8 0.0 1e-14 54.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 OAP65655.1 - 8e-13 48.6 0.0 1.6e-12 47.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OAP65655.1 - 2.4e-09 37.3 0.0 3.6e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OAP65655.1 - 4.6e-08 33.2 0.0 7.3e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 OAP65655.1 - 6.8e-08 32.7 0.3 3.5e-07 30.4 0.1 2.1 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAP65655.1 - 0.00028 20.9 0.0 0.00053 20.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 OAP65655.1 - 0.059 13.7 0.0 0.57 10.5 0.0 2.2 2 0 0 2 2 2 0 Outer mitochondrial membrane transport complex protein Beach PF02138.18 OAP65656.1 - 1.6e-120 401.6 0.0 2.9e-120 400.8 0.0 1.4 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 OAP65656.1 - 1.5e-10 41.1 0.0 5e-10 39.4 0.0 2.0 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.6 OAP65656.1 - 1.2e-09 38.5 0.0 4e-09 36.8 0.0 1.9 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily eIF-5a PF01287.20 OAP65656.1 - 4.1e-07 30.0 0.3 3.4e-06 27.0 0.1 2.5 2 0 0 2 2 2 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold WD40 PF00400.32 OAP65656.1 - 5.4e-07 30.2 0.5 0.0086 16.9 0.0 4.2 3 0 0 3 3 3 2 WD domain, G-beta repeat DUF4800 PF16057.5 OAP65656.1 - 5 6.3 8.0 1.9 7.7 3.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4800) Glyco_transf_54 PF04666.13 OAP65657.1 - 5.7e-09 35.2 0.0 2.1e-07 30.1 0.0 2.4 2 1 0 2 2 2 1 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region S-antigen PF05756.11 OAP65658.1 - 0.89 10.0 2.6 1.7 9.1 2.6 1.3 1 0 0 1 1 1 0 S-antigen protein LicD PF04991.13 OAP65659.1 - 8.7e-25 88.2 1.4 3.2e-16 60.2 1.1 2.1 1 1 1 2 2 2 2 LicD family Isochorismatase PF00857.20 OAP65660.1 - 9.5e-39 133.4 0.0 1.1e-38 133.1 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family DUF4479 PF14794.6 OAP65660.1 - 0.0035 17.1 0.0 0.0095 15.8 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4479) SRR1 PF07985.12 OAP65661.1 - 1.6e-09 37.7 0.0 2.8e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 SRR1 RRP7 PF12923.7 OAP65661.1 - 0.01 16.0 0.1 0.018 15.2 0.1 1.4 1 0 0 1 1 1 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain adh_short PF00106.25 OAP65662.1 - 6.5e-22 78.0 0.2 9.1e-22 77.5 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAP65662.1 - 3.2e-16 59.6 0.0 3.9e-16 59.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAP65662.1 - 3.1e-05 24.0 0.0 4.7e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAP65662.1 - 0.0016 18.0 0.9 0.025 14.0 0.9 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 OAP65662.1 - 0.026 14.4 0.3 0.054 13.4 0.3 1.6 1 1 0 1 1 1 0 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 OAP65662.1 - 0.078 13.2 0.1 0.27 11.5 0.1 1.8 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain AAA_12 PF13087.6 OAP65664.1 - 1e-36 126.5 0.0 2e-36 125.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 OAP65664.1 - 1.6e-20 74.0 2.7 2.1e-11 44.1 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_30 PF13604.6 OAP65664.1 - 7.9e-09 35.5 0.0 6.6e-07 29.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 OAP65664.1 - 5.5e-08 33.3 0.0 5.1e-06 26.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 OAP65664.1 - 4.4e-06 26.6 0.0 0.023 14.5 0.0 3.3 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 OAP65664.1 - 4.5e-05 23.5 0.0 0.00015 21.8 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 OAP65664.1 - 0.005 16.6 0.0 0.0097 15.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase PhoH PF02562.16 OAP65664.1 - 0.0056 16.1 0.0 0.01 15.3 0.0 1.3 1 0 0 1 1 1 1 PhoH-like protein AAA_16 PF13191.6 OAP65664.1 - 0.015 15.7 0.0 0.035 14.5 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain DUF2075 PF09848.9 OAP65664.1 - 0.044 13.0 0.0 0.23 10.6 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_5 PF07728.14 OAP65664.1 - 0.047 13.7 0.0 0.24 11.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 OAP65664.1 - 0.069 13.4 0.0 0.66 10.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 OAP65664.1 - 0.16 12.4 0.0 0.6 10.5 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) WD40 PF00400.32 OAP65665.1 - 1.3e-13 51.2 8.4 1.2 10.1 0.1 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAP65665.1 - 0.0006 20.1 0.0 4.6 7.6 0.0 3.9 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PALB2_WD40 PF16756.5 OAP65665.1 - 0.057 12.3 0.0 0.74 8.7 0.0 2.0 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain Glyco_hydro_17 PF00332.18 OAP65667.1 - 7.2e-10 38.9 3.0 6.2e-07 29.3 3.0 2.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 Presenilin PF01080.17 OAP65668.1 - 0.12 11.1 25.8 0.23 10.2 25.8 1.5 1 0 0 1 1 1 0 Presenilin NARP1 PF12569.8 OAP65668.1 - 0.21 10.4 15.5 0.33 9.8 15.5 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 SpoIIP PF07454.11 OAP65668.1 - 0.35 10.3 20.7 1 8.8 19.2 2.2 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) eIF-3_zeta PF05091.12 OAP65668.1 - 0.37 9.7 25.3 0.76 8.7 25.3 1.5 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) PPL5 PF18168.1 OAP65668.1 - 0.43 9.8 10.7 1.1 8.5 10.7 1.7 1 0 0 1 1 1 0 Prim-pol family 5 DUF4638 PF15472.6 OAP65668.1 - 0.49 10.1 13.0 1.4 8.6 13.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) RR_TM4-6 PF06459.12 OAP65668.1 - 0.81 9.5 25.4 1.6 8.5 25.4 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Otopetrin PF03189.13 OAP65668.1 - 0.87 8.3 7.6 1.5 7.5 7.6 1.3 1 0 0 1 1 1 0 Otopetrin CDC45 PF02724.14 OAP65668.1 - 1 7.6 14.1 1.6 6.9 14.1 1.2 1 0 0 1 1 1 0 CDC45-like protein Membralin PF09746.9 OAP65668.1 - 1.6 7.7 11.9 2.6 7.0 11.9 1.3 1 0 0 1 1 1 0 Tumour-associated protein DUF4407 PF14362.6 OAP65668.1 - 2.8 7.2 20.6 5.2 6.3 20.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Tim54 PF11711.8 OAP65668.1 - 3.4 6.4 20.1 7.3 5.3 20.1 1.6 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 SLC12 PF03522.15 OAP65668.1 - 6 5.8 24.1 11 5.0 24.1 1.4 1 0 0 1 1 1 0 Solute carrier family 12 DUF4746 PF15928.5 OAP65668.1 - 7.4 5.9 17.2 23 4.3 17.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DHHC PF01529.20 OAP65670.1 - 2.1e-27 95.8 3.7 2.1e-27 95.8 3.7 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase CitMHS PF03600.16 OAP65670.1 - 0.011 14.9 0.0 0.016 14.4 0.0 1.2 1 0 0 1 1 1 0 Citrate transporter DUF4131 PF13567.6 OAP65670.1 - 0.67 9.6 4.1 0.54 9.9 0.2 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) HemY_N PF07219.13 OAP65670.1 - 7.2 6.9 6.7 5.1 7.3 0.0 3.0 3 0 0 3 3 3 0 HemY protein N-terminus FtsK_4TM PF13491.6 OAP65670.1 - 8.6 6.0 9.4 5.5 6.7 2.8 2.1 2 0 0 2 2 2 0 4TM region of DNA translocase FtsK/SpoIIIE TAL_FSA PF00923.19 OAP65671.1 - 1.3e-96 323.3 0.0 1.5e-96 323.1 0.0 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase Lsm_interact PF05391.11 OAP65672.1 - 0.016 14.7 0.8 0.14 11.7 0.8 2.8 1 0 0 1 1 1 0 Lsm interaction motif Abhydrolase_1 PF00561.20 OAP65673.1 - 6.3e-18 65.3 0.1 2.3e-15 57.0 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAP65673.1 - 1.5e-17 65.0 7.9 4.7e-16 60.1 7.9 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAP65673.1 - 3.4e-11 42.9 0.0 6.6e-10 38.6 0.0 2.3 3 0 0 3 3 3 1 Serine aminopeptidase, S33 Esterase PF00756.20 OAP65673.1 - 0.012 15.2 0.0 0.02 14.6 0.0 1.3 1 0 0 1 1 1 0 Putative esterase UQ_con PF00179.26 OAP65674.1 - 4e-39 133.5 0.0 5.3e-39 133.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 OAP65674.1 - 0.085 13.1 1.4 0.11 12.8 0.0 2.0 2 0 0 2 2 2 0 RWD domain ABC_tran PF00005.27 OAP65675.1 - 1e-53 181.5 0.2 4.6e-30 104.9 0.1 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 OAP65675.1 - 1.3e-53 182.4 26.1 3.9e-34 118.6 7.6 3.4 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 OAP65675.1 - 1e-07 31.6 2.2 0.013 14.9 0.1 4.1 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 OAP65675.1 - 7.1e-07 29.9 0.7 0.0013 19.3 0.1 2.6 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.6 OAP65675.1 - 2.2e-06 27.7 1.1 0.071 12.9 0.0 3.0 2 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 OAP65675.1 - 4.2e-06 26.8 0.0 0.009 15.9 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 OAP65675.1 - 6.7e-06 26.4 0.3 2.1 8.6 0.0 3.6 3 0 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.23 OAP65675.1 - 5.8e-05 23.2 0.3 0.069 13.2 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 OAP65675.1 - 0.00051 19.7 0.5 1.1 9.1 0.1 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF87 PF01935.17 OAP65675.1 - 0.0036 17.4 2.0 0.023 14.8 0.1 2.8 2 1 0 2 2 2 1 Helicase HerA, central domain AAA_16 PF13191.6 OAP65675.1 - 0.0037 17.7 0.6 3.8 7.9 0.0 3.1 2 1 0 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.12 OAP65675.1 - 0.0045 16.3 0.3 0.59 9.4 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin IstB_IS21 PF01695.17 OAP65675.1 - 0.0047 16.7 0.0 2.3 7.9 0.0 2.7 2 0 0 2 2 2 1 IstB-like ATP binding protein T2SSE PF00437.20 OAP65675.1 - 0.0053 15.8 0.1 0.12 11.5 0.1 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_25 PF13481.6 OAP65675.1 - 0.0089 15.6 1.0 3.1 7.3 0.1 3.1 3 0 0 3 3 3 1 AAA domain AAA_7 PF12775.7 OAP65675.1 - 0.032 13.7 0.1 3.3 7.2 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region cobW PF02492.19 OAP65675.1 - 0.051 13.2 1.2 0.37 10.4 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.29 OAP65675.1 - 0.061 13.7 0.8 8.5 6.8 0.0 3.5 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 OAP65675.1 - 0.09 12.5 0.1 4.3 7.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.9 OAP65675.1 - 0.1 11.5 1.5 1.5 7.6 0.2 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_15 PF13175.6 OAP65675.1 - 0.17 11.6 0.0 3.3 7.3 0.0 2.5 2 1 0 2 2 2 0 AAA ATPase domain AAA_30 PF13604.6 OAP65675.1 - 0.17 11.6 1.6 5.6 6.6 0.0 3.0 3 0 0 3 3 3 0 AAA domain TsaE PF02367.17 OAP65675.1 - 0.19 11.7 0.6 8.5 6.4 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 OAP65675.1 - 0.33 11.5 1.0 36 4.9 0.2 2.9 2 1 0 2 2 2 0 AAA domain Abhydrolase_6 PF12697.7 OAP65676.1 - 1.2e-10 42.4 0.0 2.7e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAP65676.1 - 3e-09 36.9 0.0 1.2e-05 25.1 0.0 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAP65676.1 - 2e-05 24.0 0.1 0.015 14.6 0.1 2.4 2 0 0 2 2 2 2 Serine aminopeptidase, S33 SAP PF02037.27 OAP65678.1 - 2.5e-07 30.3 0.1 4.5e-07 29.5 0.1 1.4 1 0 0 1 1 1 1 SAP domain RSB_motif PF16294.5 OAP65678.1 - 1e-06 28.9 0.2 1e-06 28.9 0.2 4.0 4 0 0 4 4 4 1 RNSP1-SAP18 binding (RSB) motif RRM_1 PF00076.22 OAP65678.1 - 0.098 12.5 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ArfGap PF01412.18 OAP65679.1 - 8e-30 103.3 0.3 1.6e-29 102.3 0.3 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf GTP_EFTU PF00009.27 OAP65680.1 - 8.5e-40 136.4 0.0 1.4e-39 135.6 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 OAP65680.1 - 2.6e-25 88.3 0.1 5.8e-25 87.2 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 OAP65680.1 - 1e-16 60.8 0.0 1.4e-08 34.7 0.0 2.5 2 0 0 2 2 2 2 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 OAP65680.1 - 1.6e-07 31.6 0.0 6.4e-07 29.7 0.0 2.1 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 OAP65680.1 - 0.0018 18.1 0.0 0.0049 16.7 0.0 1.7 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain EFG_IV PF03764.18 OAP65680.1 - 0.012 15.4 0.0 0.11 12.3 0.0 2.4 1 1 1 2 2 2 0 Elongation factor G, domain IV PX PF00787.24 OAP65681.1 - 1.5e-09 37.9 0.0 2.6e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 OAP65681.1 - 4.4e-09 36.2 4.3 7.1e-09 35.6 4.3 1.2 1 0 0 1 1 1 1 Vps5 C terminal like NST1 PF13945.6 OAP65681.1 - 1 9.4 4.1 2.3 8.3 4.1 1.5 1 0 0 1 1 1 0 Salt tolerance down-regulator APG6_N PF17675.1 OAP65682.1 - 0.00016 22.2 0.2 0.00035 21.1 0.2 1.5 1 0 0 1 1 1 1 Apg6 coiled-coil region KASH_CCD PF14662.6 OAP65682.1 - 0.0011 18.9 1.3 0.0019 18.1 1.3 1.3 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH zf-C4H2 PF10146.9 OAP65682.1 - 0.0016 18.8 0.0 0.0033 17.8 0.0 1.5 1 0 0 1 1 1 1 Zinc finger-containing protein HOOK PF05622.12 OAP65682.1 - 0.01 14.0 0.0 0.014 13.6 0.0 1.1 1 0 0 1 1 1 0 HOOK protein DUF2353 PF09789.9 OAP65682.1 - 0.036 13.4 0.9 0.064 12.6 0.9 1.3 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) Macoilin PF09726.9 OAP65682.1 - 0.073 11.6 0.3 0.1 11.1 0.3 1.2 1 0 0 1 1 1 0 Macoilin family TMF_TATA_bd PF12325.8 OAP65682.1 - 0.1 12.8 3.2 0.19 11.9 3.2 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding ADIP PF11559.8 OAP65682.1 - 0.11 12.6 5.1 0.24 11.5 5.1 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding GHL13 PF14883.6 OAP65682.1 - 0.19 10.7 0.3 0.3 10.1 0.3 1.2 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase family 13 DUF2968 PF11180.8 OAP65682.1 - 0.33 10.6 4.6 0.64 9.6 4.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) RasGAP_C PF03836.15 OAP65682.1 - 0.43 10.7 3.1 0.69 10.0 2.6 1.5 1 1 0 1 1 1 0 RasGAP C-terminus GAS PF13851.6 OAP65682.1 - 0.61 9.4 10.3 0.022 14.1 3.6 1.9 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding PRKG1_interact PF15898.5 OAP65682.1 - 0.77 10.7 4.5 0.82 10.6 2.3 2.1 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain ZapB PF06005.12 OAP65682.1 - 0.85 10.1 10.3 0.2 12.1 3.6 2.8 3 0 0 3 3 3 0 Cell division protein ZapB YabA PF06156.13 OAP65682.1 - 1.5 9.5 4.2 2.9 8.6 2.0 2.2 1 1 1 2 2 2 0 Initiation control protein YabA Siah-Interact_N PF09032.11 OAP65682.1 - 2 8.8 5.2 1.1 9.6 2.4 2.1 2 0 0 2 2 2 0 Siah interacting protein, N terminal DivIC PF04977.15 OAP65682.1 - 4.8 7.0 9.7 0.42 10.4 4.1 2.1 2 1 0 2 2 2 0 Septum formation initiator GFA PF04828.14 OAP65683.1 - 1.6e-12 47.6 0.0 2.4e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme DiS_P_DiS PF06750.13 OAP65683.1 - 0.12 12.6 1.3 0.34 11.0 0.0 2.0 2 0 0 2 2 2 0 Bacterial Peptidase A24 N-terminal domain DUF4853 PF16145.5 OAP65684.1 - 0.033 14.3 0.0 0.037 14.2 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4853) Epimerase PF01370.21 OAP65685.1 - 6e-09 35.7 0.0 0.00073 19.1 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 OAP65685.1 - 1.1e-06 29.1 0.0 7.2e-06 26.4 0.0 2.0 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 OAP65685.1 - 0.00038 20.4 0.0 0.00094 19.1 0.0 1.6 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 OAP65685.1 - 0.0035 16.9 0.0 0.005 16.4 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family GDP_Man_Dehyd PF16363.5 OAP65685.1 - 0.049 13.0 0.1 0.11 11.9 0.0 1.6 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 OAP65685.1 - 0.13 11.4 0.0 0.25 10.5 0.0 1.6 1 1 0 1 1 1 0 Male sterility protein THOC2_N PF16134.5 OAP65686.1 - 4.3e-228 759.0 0.0 5.9e-228 758.6 0.0 1.2 1 0 0 1 1 1 1 THO complex subunit 2 N-terminus Tho2 PF11262.8 OAP65686.1 - 1.2e-98 330.1 0.0 1.9e-98 329.4 0.0 1.3 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.8 OAP65686.1 - 2.8e-25 88.2 0.0 1.1e-24 86.3 0.0 2.1 1 0 0 1 1 1 1 Transcription- and export-related complex subunit SpoVT_C PF15714.5 OAP65686.1 - 0.0016 18.5 0.4 0.0033 17.5 0.4 1.4 1 0 0 1 1 1 1 Stage V sporulation protein T C-terminal, transcription factor Sec23_trunk PF04811.15 OAP65687.1 - 1.2e-56 192.0 0.0 2.1e-56 191.2 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 OAP65687.1 - 5.7e-23 80.7 0.0 1.3e-22 79.6 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 OAP65687.1 - 1.8e-17 63.8 0.0 3.4e-17 63.0 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 OAP65687.1 - 3.4e-15 55.8 4.3 7.9e-15 54.6 4.3 1.7 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 OAP65687.1 - 1.5e-06 28.0 0.0 2.9e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat DUF1678 PF07913.11 OAP65687.1 - 0.16 11.7 0.0 0.37 10.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1678) MFS_1 PF07690.16 OAP65688.1 - 7.8e-49 166.5 36.2 7.8e-49 166.5 36.2 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAP65688.1 - 1.5e-12 47.1 1.9 1.5e-12 47.1 1.9 2.8 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 OAP65688.1 - 2.6e-09 36.1 1.1 2.6e-09 36.1 1.1 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 OAP65688.1 - 0.078 11.4 4.6 0.095 11.1 1.5 2.0 1 1 1 2 2 2 0 Transmembrane secretion effector Abhydrolase_1 PF00561.20 OAP65689.1 - 3.8e-51 174.2 0.0 8.3e-51 173.1 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAP65689.1 - 3.7e-05 24.4 3.6 8.1e-05 23.3 3.6 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAP65689.1 - 0.023 14.0 0.0 0.74 9.0 0.0 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Solute_trans_a PF03619.16 OAP65690.1 - 1.2e-89 300.3 31.1 1.5e-89 300.1 31.1 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha ERGIC_N PF13850.6 OAP65690.1 - 1.9 8.9 7.4 0.69 10.3 0.3 3.0 3 0 0 3 3 3 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Brr6_like_C_C PF10104.9 OAP65690.1 - 5.8 6.7 12.3 2.5 7.9 1.0 3.3 3 1 0 3 3 3 0 Di-sulfide bridge nucleocytoplasmic transport domain Cu_amine_oxid PF01179.20 OAP65691.1 - 3e-158 527.0 0.0 3.8e-158 526.7 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.16 OAP65691.1 - 2.7e-08 33.9 0.0 5.3e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.16 OAP65691.1 - 2e-06 28.1 0.0 4.8e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Lactamase_B_6 PF16661.5 OAP65693.1 - 5.5e-64 215.2 0.0 8.3e-64 214.6 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 OAP65693.1 - 1.5e-39 135.9 0.0 1.5e-39 135.9 0.0 2.9 3 0 0 3 3 3 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.8 OAP65693.1 - 5.2e-15 55.7 0.0 1.6e-14 54.1 0.0 1.9 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.12 OAP65693.1 - 3.6e-11 42.8 0.0 9.1e-11 41.5 0.0 1.7 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B PF00753.27 OAP65693.1 - 0.014 15.4 0.0 0.043 13.8 0.0 1.8 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily Cwf_Cwc_15 PF04889.12 OAP65693.1 - 2.5 7.8 19.9 1.5 8.5 4.9 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein eIF-3c_N PF05470.12 OAP65693.1 - 8.5 4.6 6.1 1.3 7.3 0.4 1.9 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Swi5 PF07061.11 OAP65694.1 - 2.1e-15 56.5 13.9 3e-12 46.4 13.9 3.0 1 1 0 1 1 1 1 Swi5 SOG2 PF10428.9 OAP65694.1 - 0.022 14.0 13.5 0.026 13.8 13.5 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein CCM2_C PF16545.5 OAP65694.1 - 0.036 14.6 0.3 14 6.2 0.2 2.2 2 0 0 2 2 2 0 Cerebral cavernous malformation protein, harmonin-homology DUF4407 PF14362.6 OAP65694.1 - 0.52 9.6 8.3 0.62 9.4 8.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Macoilin PF09726.9 OAP65694.1 - 7.9 4.9 14.0 8.7 4.8 14.0 1.0 1 0 0 1 1 1 0 Macoilin family Presenilin PF01080.17 OAP65694.1 - 9.6 4.8 9.9 13 4.4 9.9 1.3 1 0 0 1 1 1 0 Presenilin ABC_membrane PF00664.23 OAP65695.1 - 1.5e-98 329.9 33.2 5.9e-52 177.0 17.0 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 OAP65695.1 - 1.2e-67 226.6 0.0 2.2e-32 112.4 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 OAP65695.1 - 1.5e-13 50.7 0.0 2e-05 24.2 0.1 3.8 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 OAP65695.1 - 1.1e-06 29.1 2.9 0.012 16.0 0.1 3.2 2 2 0 2 2 2 2 AAA ATPase domain ABC_ATPase PF09818.9 OAP65695.1 - 3.8e-06 26.0 2.6 0.028 13.2 0.1 3.1 3 1 0 3 3 3 2 Predicted ATPase of the ABC class AAA_29 PF13555.6 OAP65695.1 - 4.2e-06 26.4 3.9 0.0058 16.4 0.2 3.3 3 0 0 3 3 3 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 OAP65695.1 - 1.1e-05 25.5 0.0 0.049 13.5 0.0 2.8 2 0 0 2 2 2 2 RsgA GTPase AAA_21 PF13304.6 OAP65695.1 - 2.8e-05 24.1 3.6 0.042 13.7 0.0 3.9 2 2 2 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system DUF87 PF01935.17 OAP65695.1 - 5.6e-05 23.3 1.1 0.033 14.3 0.4 2.9 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_22 PF13401.6 OAP65695.1 - 0.00012 22.4 7.1 0.15 12.3 0.1 5.2 4 2 0 4 4 4 2 AAA domain AAA_25 PF13481.6 OAP65695.1 - 0.00019 21.1 0.4 0.096 12.3 0.0 3.0 3 0 0 3 3 3 1 AAA domain Zeta_toxin PF06414.12 OAP65695.1 - 0.00024 20.4 0.3 0.38 10.0 0.0 3.1 3 0 0 3 3 3 2 Zeta toxin AAA_15 PF13175.6 OAP65695.1 - 0.00037 20.3 0.1 0.88 9.2 0.1 2.9 2 1 0 2 2 2 2 AAA ATPase domain AAA_28 PF13521.6 OAP65695.1 - 0.0023 18.2 0.0 0.35 11.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 OAP65695.1 - 0.0028 18.2 0.0 3.7 8.1 0.0 2.9 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 OAP65695.1 - 0.003 17.7 2.3 2.7 8.3 0.2 3.7 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit G-alpha PF00503.20 OAP65695.1 - 0.0039 16.4 0.0 2.9 6.9 0.0 2.3 2 0 0 2 2 2 2 G-protein alpha subunit AAA_33 PF13671.6 OAP65695.1 - 0.0042 17.3 0.0 1.5 9.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 OAP65695.1 - 0.006 16.1 0.0 3.9 7.0 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_5 PF07728.14 OAP65695.1 - 0.027 14.5 0.2 16 5.5 0.0 3.1 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) DUF815 PF05673.13 OAP65695.1 - 0.04 13.1 0.0 9.2 5.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) RNA_helicase PF00910.22 OAP65695.1 - 0.049 14.0 0.1 13 6.2 0.0 3.6 3 0 0 3 3 3 0 RNA helicase AAA_23 PF13476.6 OAP65695.1 - 0.068 13.7 1.4 5.1 7.5 0.0 3.2 3 0 0 3 3 2 0 AAA domain PRK PF00485.18 OAP65695.1 - 0.068 12.9 0.3 2.7 7.7 0.0 2.8 3 0 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family APS_kinase PF01583.20 OAP65695.1 - 0.093 12.6 0.3 2.6 7.9 0.1 3.0 2 1 1 3 3 3 0 Adenylylsulphate kinase AAA_24 PF13479.6 OAP65695.1 - 0.14 11.9 0.1 10 5.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 OAP65695.1 - 0.19 11.6 0.6 0.78 9.6 0.0 2.3 3 0 0 3 3 2 0 Rad17 P-loop domain FtsK_SpoIIIE PF01580.18 OAP65695.1 - 0.29 10.4 1.9 15 4.9 0.1 3.1 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_30 PF13604.6 OAP65695.1 - 0.3 10.8 10.7 2 8.1 0.1 4.0 5 0 0 5 5 4 0 AAA domain MMR_HSR1 PF01926.23 OAP65695.1 - 0.35 11.0 1.4 24 5.0 0.0 3.2 3 0 0 3 3 3 0 50S ribosome-binding GTPase ECH_1 PF00378.20 OAP65696.1 - 5.3e-22 78.3 0.0 6.3e-22 78.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAP65696.1 - 0.0011 18.5 0.0 0.0018 17.9 0.0 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Ysc84 PF04366.12 OAP65697.1 - 1.4e-42 144.5 0.1 2.4e-42 143.7 0.1 1.4 1 0 0 1 1 1 1 Las17-binding protein actin regulator Polysacc_deac_3 PF15421.6 OAP65697.1 - 0.1 11.1 0.0 0.14 10.6 0.0 1.1 1 0 0 1 1 1 0 Putative polysaccharide deacetylase Polysacc_deac_1 PF01522.21 OAP65698.1 - 7e-31 106.7 0.0 4.5e-30 104.1 0.0 2.1 2 0 0 2 2 2 1 Polysaccharide deacetylase DUF2334 PF10096.9 OAP65698.1 - 0.033 13.8 0.0 0.062 13.0 0.0 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) Ytp1 PF10355.9 OAP65699.1 - 6.5e-71 238.8 15.5 1.9e-70 237.2 15.5 1.7 1 1 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 OAP65699.1 - 5e-30 103.4 0.2 5e-30 103.4 0.2 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) AWPM-19 PF05512.11 OAP65699.1 - 0.011 15.9 0.9 0.033 14.4 0.0 2.2 2 0 0 2 2 2 0 AWPM-19-like family TctB PF07331.11 OAP65699.1 - 0.023 15.0 0.8 0.023 15.0 0.8 3.5 2 1 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family Pex2_Pex12 PF04757.14 OAP65700.1 - 6.5e-43 146.9 2.5 8.6e-43 146.5 2.5 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.6 OAP65700.1 - 5.2e-11 42.2 6.4 7.6e-11 41.7 6.4 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAP65700.1 - 1.1e-10 41.6 10.0 1.9e-10 40.9 10.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 OAP65700.1 - 3.2e-10 39.7 9.6 5.5e-10 38.9 9.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAP65700.1 - 5.7e-10 38.9 7.5 1.1e-09 38.0 7.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAP65700.1 - 7.3e-09 35.4 7.2 1.2e-08 34.8 7.2 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 OAP65700.1 - 2.2e-08 34.0 7.9 4.5e-08 33.0 7.9 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 OAP65700.1 - 7.9e-08 32.1 6.8 1.2e-07 31.5 6.8 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 OAP65700.1 - 1.2e-06 28.7 7.2 2.4e-06 27.7 7.2 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 OAP65700.1 - 2.2e-06 27.7 8.6 3.9e-06 26.9 8.6 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 OAP65700.1 - 0.0061 16.6 3.8 0.012 15.7 3.8 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.8 OAP65700.1 - 0.0078 16.0 3.7 0.014 15.2 3.7 1.3 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.6 OAP65700.1 - 0.012 15.5 2.9 0.023 14.6 2.9 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 OAP65700.1 - 0.016 15.0 6.8 0.036 13.8 6.8 1.5 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_10 PF16685.5 OAP65700.1 - 0.075 13.2 6.5 0.14 12.3 6.5 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 FYVE PF01363.21 OAP65700.1 - 0.59 10.3 6.3 1.5 9.0 6.3 1.7 1 1 0 1 1 1 0 FYVE zinc finger Zn_ribbon_17 PF17120.5 OAP65700.1 - 1.1 9.0 6.5 1.9 8.2 6.5 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type IBR PF01485.21 OAP65700.1 - 3.3 8.0 8.5 5.5 7.3 7.7 1.8 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain Abhydrolase_3 PF07859.13 OAP65701.1 - 8e-37 127.1 0.0 1e-36 126.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 OAP65701.1 - 5.6e-06 25.5 0.0 0.017 14.0 0.0 2.1 2 0 0 2 2 2 2 Carboxylesterase family Methyltransf_23 PF13489.6 OAP65702.1 - 1.1e-17 64.3 0.0 1.9e-17 63.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAP65702.1 - 6e-12 46.1 0.0 1.7e-11 44.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAP65702.1 - 2e-10 41.2 0.0 4e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAP65702.1 - 2.8e-08 33.7 0.0 0.0056 16.5 0.0 2.4 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 OAP65702.1 - 5.3e-07 30.3 0.0 6.6e-06 26.8 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OAP65702.1 - 0.00083 18.9 0.0 0.0017 17.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_16 PF10294.9 OAP65702.1 - 0.0027 17.4 0.0 0.0044 16.8 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Ubie_methyltran PF01209.18 OAP65702.1 - 0.007 15.7 0.0 0.31 10.3 0.0 2.7 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 OAP65702.1 - 0.011 15.9 0.0 0.029 14.5 0.0 1.7 2 0 0 2 2 2 0 FtsJ-like methyltransferase Methyltransf_2 PF00891.18 OAP65702.1 - 0.012 14.9 0.0 0.021 14.1 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase domain PrmA PF06325.13 OAP65702.1 - 0.16 11.3 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 OAP65703.1 - 0.00014 21.7 0.0 0.00024 20.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmC_N PF17827.1 OAP65703.1 - 0.002 18.7 0.0 0.16 12.6 0.0 2.5 2 0 0 2 2 2 1 PrmC N-terminal domain MTS PF05175.14 OAP65703.1 - 0.0022 17.6 3.5 1.5 8.4 0.5 3.8 2 1 1 3 3 3 1 Methyltransferase small domain PrmA PF06325.13 OAP65703.1 - 0.025 14.0 0.5 0.09 12.2 0.8 1.6 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 OAP65703.1 - 0.046 14.4 0.2 0.53 11.0 0.2 2.3 1 1 0 1 1 1 0 Methyltransferase domain N6_Mtase PF02384.16 OAP65703.1 - 0.047 13.0 0.0 0.27 10.5 0.0 2.1 2 1 0 2 2 2 0 N-6 DNA Methylase Polysacc_deac_1 PF01522.21 OAP65704.1 - 2e-22 79.4 0.0 3.5e-22 78.6 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 OAP65704.1 - 7.8e-11 42.0 0.6 1.8e-10 40.9 0.3 1.7 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2334) Glyco_hydro_57 PF03065.15 OAP65704.1 - 0.00082 18.7 0.8 0.0024 17.1 0.1 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 57 DUF2194 PF09960.9 OAP65704.1 - 0.15 10.4 0.0 0.19 10.1 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2194) COX5A PF02284.16 OAP65706.1 - 2.3e-41 139.9 0.3 3e-41 139.6 0.3 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va LTV PF04180.14 OAP65706.1 - 0.069 12.9 0.4 0.1 12.3 0.4 1.3 1 1 0 1 1 1 0 Low temperature viability protein ELO PF01151.18 OAP65707.1 - 5.4e-63 212.8 22.5 6.3e-63 212.6 22.5 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family GATase_5 PF13507.6 OAP65708.1 - 1.7e-88 296.1 0.0 3.4e-88 295.1 0.0 1.5 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 OAP65708.1 - 1.6e-41 142.1 0.0 3.3e-29 102.0 0.2 2.4 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 OAP65708.1 - 5.7e-36 123.0 0.0 1.2e-35 121.9 0.0 1.6 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 OAP65708.1 - 4.4e-21 75.2 0.0 1e-20 74.0 0.0 1.7 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain AIRS PF00586.24 OAP65708.1 - 0.066 13.9 0.1 0.35 11.6 0.0 2.3 2 0 0 2 2 2 0 AIR synthase related protein, N-terminal domain Sugar_tr PF00083.24 OAP65709.1 - 2.5e-102 343.1 15.1 3e-102 342.8 15.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP65709.1 - 2.3e-32 112.3 46.1 5.7e-28 97.9 20.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 OAP65709.1 - 0.0036 16.2 5.3 0.079 11.8 2.9 2.3 1 1 1 2 2 2 2 MFS_1 like family Mito_carr PF00153.27 OAP65711.1 - 7e-18 64.3 1.8 5.5e-11 42.2 0.0 3.3 3 1 0 3 3 3 2 Mitochondrial carrier protein POR_N PF01855.19 OAP65711.1 - 0.68 9.6 3.5 21 4.8 2.9 2.1 2 0 0 2 2 2 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg SPT16 PF08644.11 OAP65712.1 - 2.4e-56 190.1 0.1 2.4e-56 190.1 0.1 2.6 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.6 OAP65712.1 - 1.3e-49 168.1 0.3 1.3e-49 168.1 0.3 2.5 3 0 0 3 3 3 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.24 OAP65712.1 - 1.9e-28 99.6 0.0 3.7e-28 98.7 0.0 1.5 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 OAP65712.1 - 3.1e-14 53.1 0.1 1.1e-13 51.3 0.0 2.0 2 0 0 2 2 2 1 Histone chaperone Rttp106-like DUF3504 PF12012.8 OAP65712.1 - 6.4 6.7 8.1 7.8 6.4 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3504) DUF1640 PF07798.11 OAP65715.1 - 0.00023 21.3 0.3 0.00029 20.9 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) CwsA PF10814.8 OAP65715.1 - 0.0026 17.9 0.0 0.0052 17.0 0.0 1.5 1 1 0 1 1 1 1 Cell wall synthesis protein CwsA Rab5-bind PF09311.11 OAP65715.1 - 0.0092 15.4 0.7 0.013 14.9 0.7 1.2 1 0 0 1 1 1 1 Rabaptin-like protein DUF2730 PF10805.8 OAP65715.1 - 0.012 15.7 0.5 0.021 14.9 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) Fzo_mitofusin PF04799.13 OAP65715.1 - 0.017 14.7 1.3 0.041 13.4 1.3 1.7 1 1 0 1 1 1 0 fzo-like conserved region DUF5082 PF16888.5 OAP65715.1 - 0.019 15.2 0.2 0.64 10.3 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) DUF1664 PF07889.12 OAP65715.1 - 0.021 14.8 0.4 0.035 14.2 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 OAP65715.1 - 0.025 14.6 0.1 0.074 13.1 0.1 1.7 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus TMPIT PF07851.13 OAP65715.1 - 0.05 12.8 0.1 0.065 12.5 0.1 1.1 1 0 0 1 1 1 0 TMPIT-like protein Rootletin PF15035.6 OAP65715.1 - 0.071 13.1 1.1 0.097 12.7 1.1 1.2 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion COG2 PF06148.11 OAP65715.1 - 0.081 13.0 0.9 0.37 10.9 0.9 1.8 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 SF-assemblin PF06705.11 OAP65715.1 - 0.096 12.0 1.1 0.44 9.8 1.0 1.5 1 1 0 1 1 1 0 SF-assemblin/beta giardin CdvA PF18822.1 OAP65715.1 - 0.12 12.2 1.9 7.8 6.3 0.2 2.1 1 1 1 2 2 2 0 CdvA-like coiled-coil domain Phage_Mu_Gam PF07352.12 OAP65715.1 - 0.12 12.3 0.1 0.24 11.3 0.1 1.5 1 1 0 1 1 1 0 Bacteriophage Mu Gam like protein PKK PF12474.8 OAP65715.1 - 0.14 12.3 1.6 0.2 11.8 1.6 1.3 1 0 0 1 1 1 0 Polo kinase kinase Tyrosinase PF00264.20 OAP65717.1 - 5.1e-40 138.1 0.0 7e-40 137.7 0.0 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase SUI1 PF01253.22 OAP65718.1 - 3.6e-19 69.0 0.3 8.4e-19 67.9 0.0 1.8 2 0 0 2 2 2 1 Translation initiation factor SUI1 Pre-PUA PF17832.1 OAP65718.1 - 1.4e-09 38.5 0.1 4.7e-08 33.6 0.1 2.4 1 1 0 1 1 1 1 Pre-PUA-like domain Kin17_mid PF10357.9 OAP65718.1 - 0.036 14.0 0.0 0.071 13.0 0.0 1.4 1 0 0 1 1 1 0 Domain of Kin17 curved DNA-binding protein DUF1264 PF06884.11 OAP65719.1 - 2.8e-65 219.1 0.1 3.4e-65 218.8 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1264) DUF2767 PF10965.8 OAP65719.1 - 0.02 14.9 0.0 0.037 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2767) adh_short_C2 PF13561.6 OAP65720.1 - 4.5e-59 199.9 0.0 5.7e-59 199.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAP65720.1 - 3.3e-47 160.5 0.0 4.3e-47 160.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAP65720.1 - 3.8e-07 30.2 0.0 6.6e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAP65720.1 - 0.00068 19.2 0.0 0.0014 18.2 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 OAP65720.1 - 0.027 14.4 0.1 0.038 13.9 0.1 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 OAP65720.1 - 0.073 13.3 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain Velvet PF11754.8 OAP65721.1 - 5.1e-48 164.2 3.8 1.6e-31 110.2 0.0 3.1 2 1 1 3 3 3 2 Velvet factor His_Phos_2 PF00328.22 OAP65724.1 - 0.0062 15.9 0.0 0.88 8.9 0.0 2.5 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) FAD_binding_2 PF00890.24 OAP65725.1 - 2.9e-120 402.2 5.1 3.8e-120 401.8 5.1 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 OAP65725.1 - 2.1e-41 140.9 0.3 3.1e-41 140.3 0.3 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 OAP65725.1 - 1e-05 25.0 0.2 0.0029 16.9 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAP65725.1 - 7e-05 22.6 0.3 0.00016 21.4 0.2 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 OAP65725.1 - 0.0042 15.8 0.6 0.38 9.4 0.3 2.9 3 0 0 3 3 3 1 HI0933-like protein FAD_binding_3 PF01494.19 OAP65725.1 - 0.0079 15.5 1.0 0.013 14.8 1.0 1.3 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 OAP65725.1 - 0.0097 15.0 2.2 0.19 10.8 2.7 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.17 OAP65725.1 - 0.011 15.0 0.9 0.25 10.5 0.2 2.4 2 0 0 2 2 2 0 Thi4 family Pyr_redox_3 PF13738.6 OAP65725.1 - 0.11 11.7 0.7 0.95 8.7 0.1 2.5 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Ribonucleas_3_3 PF14622.6 OAP65726.1 - 4.8e-16 59.1 0.0 1.5e-07 31.7 0.0 2.2 2 0 0 2 2 2 2 Ribonuclease-III-like Ribonuclease_3 PF00636.26 OAP65726.1 - 0.16 12.6 0.4 29 5.4 0.0 2.8 2 1 1 3 3 3 0 Ribonuclease III domain Adap_comp_sub PF00928.21 OAP65727.1 - 9.8e-93 310.3 0.0 2e-92 309.3 0.0 1.5 2 0 0 2 2 2 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 OAP65727.1 - 3.6e-09 36.7 0.3 6.1e-09 35.9 0.3 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Ank_4 PF13637.6 OAP65728.1 - 2.6e-14 53.4 0.3 2.1e-07 31.3 0.1 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 OAP65728.1 - 5e-13 48.8 1.7 1.2e-08 35.0 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 OAP65728.1 - 5.3e-13 49.4 0.1 2.2e-11 44.2 0.1 2.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OAP65728.1 - 4.6e-12 45.9 0.4 1.3e-10 41.3 0.1 2.7 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAP65728.1 - 2.7e-09 36.5 0.1 5.3e-07 29.4 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat p450 PF00067.22 OAP65729.1 - 1.9e-15 56.6 0.0 1e-08 34.4 0.0 3.2 2 2 0 2 2 2 2 Cytochrome P450 Ribosom_S30AE_C PF16321.5 OAP65729.1 - 0.17 11.6 0.8 0.36 10.5 0.8 1.5 1 0 0 1 1 1 0 Sigma 54 modulation/S30EA ribosomal protein C terminus RNA12 PF10443.9 OAP65730.1 - 7.5e-170 565.4 1.5 1.2e-169 564.7 1.5 1.3 1 0 0 1 1 1 1 RNA12 protein RRM_1 PF00076.22 OAP65730.1 - 2.3e-06 27.3 0.0 1.7e-05 24.6 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ATPase_2 PF01637.18 OAP65730.1 - 9.2e-06 25.7 0.0 9.2e-05 22.5 0.0 2.4 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea DUF2487 PF10673.9 OAP65730.1 - 0.0043 17.1 0.0 0.0096 16.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2487) DBD_Tnp_Hermes PF10683.9 OAP65730.1 - 0.027 14.2 0.1 0.077 12.7 0.0 1.7 2 0 0 2 2 2 0 Hermes transposase DNA-binding domain DUF3128 PF11326.8 OAP65731.1 - 5.5e-26 90.7 5.6 5.5e-26 90.7 5.6 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3128) NRN1 PF15056.6 OAP65731.1 - 0.051 13.7 2.1 6.8 6.9 2.5 2.4 1 1 1 2 2 2 0 Neuritin protein family DUF5321 PF17254.2 OAP65731.1 - 0.89 9.0 5.3 0.17 11.3 0.3 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5321) Methyltransf_25 PF13649.6 OAP65732.1 - 2e-17 63.7 0.1 4.1e-17 62.7 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAP65732.1 - 2.9e-14 53.2 0.0 4.2e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAP65732.1 - 1.5e-13 51.2 0.0 2e-12 47.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAP65732.1 - 7.4e-12 45.3 0.0 1.4e-11 44.5 0.0 1.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAP65732.1 - 1.2e-11 45.2 0.0 2e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Pox_MCEL PF03291.16 OAP65732.1 - 7.1e-06 25.3 0.0 9.7e-06 24.9 0.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme Ubie_methyltran PF01209.18 OAP65732.1 - 2.5e-05 23.7 0.0 4.6e-05 22.9 0.0 1.3 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family NodS PF05401.11 OAP65732.1 - 0.00025 20.7 0.0 0.0027 17.4 0.0 2.0 1 1 0 1 1 1 1 Nodulation protein S (NodS) MTS PF05175.14 OAP65732.1 - 0.0013 18.3 0.0 0.056 13.0 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_PK PF05891.12 OAP65732.1 - 0.0017 17.9 0.0 0.0027 17.3 0.0 1.2 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase PrmA PF06325.13 OAP65732.1 - 0.003 17.0 0.0 0.0044 16.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_9 PF08003.11 OAP65732.1 - 0.0032 16.4 0.0 0.0049 15.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Bmt2 PF11968.8 OAP65732.1 - 0.0068 16.3 0.0 0.014 15.3 0.0 1.4 2 0 0 2 2 2 1 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 NNMT_PNMT_TEMT PF01234.17 OAP65732.1 - 0.086 12.0 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family PCMT PF01135.19 OAP65732.1 - 0.1 12.3 0.0 0.3 10.8 0.0 1.7 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) GST_C_3 PF14497.6 OAP65733.1 - 2.2e-16 59.9 0.1 3.1e-16 59.4 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OAP65733.1 - 1.3e-05 25.3 0.2 0.00069 19.8 0.0 2.3 1 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 OAP65733.1 - 6.6e-05 23.2 0.0 0.00018 21.8 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAP65733.1 - 8.9e-05 22.4 0.1 0.0002 21.3 0.1 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 OAP65733.1 - 0.07 13.5 0.0 0.3 11.5 0.0 1.9 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain GMC_oxred_N PF00732.19 OAP65734.1 - 1.7e-65 221.3 0.0 2.4e-65 220.8 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAP65734.1 - 4.4e-30 105.1 0.1 8e-30 104.3 0.1 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 OAP65734.1 - 3.6e-05 23.0 0.1 5.5e-05 22.4 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 OAP65734.1 - 0.00036 20.2 0.2 0.0072 15.9 0.3 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OAP65734.1 - 0.00038 19.7 2.8 0.059 12.4 0.8 2.3 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 OAP65734.1 - 0.00043 20.4 0.1 0.0015 18.7 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAP65734.1 - 0.01 15.1 0.1 0.028 13.7 0.1 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAP65734.1 - 0.019 14.2 0.1 0.043 13.1 0.1 1.5 1 0 0 1 1 1 0 Thi4 family TrkA_N PF02254.18 OAP65734.1 - 0.11 12.8 0.1 0.31 11.3 0.1 1.8 2 0 0 2 2 2 0 TrkA-N domain HI0933_like PF03486.14 OAP65734.1 - 0.25 10.0 0.4 7.2 5.2 0.1 2.1 2 0 0 2 2 2 0 HI0933-like protein Radical_SAM PF04055.21 OAP65736.1 - 2.2e-10 41.2 0.0 3.4e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 OAP65736.1 - 5.5e-05 23.5 0.0 9.2e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 OAP65736.1 - 0.024 14.8 0.0 0.069 13.3 0.0 1.7 2 0 0 2 2 2 0 4Fe-4S single cluster domain DUF92 PF01940.16 OAP65737.1 - 1.2e-79 267.1 9.6 1.4e-79 266.9 9.6 1.0 1 0 0 1 1 1 1 Integral membrane protein DUF92 Asp PF00026.23 OAP65739.1 - 2.1e-13 50.4 0.0 3.5e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease SKG6 PF08693.10 OAP65739.1 - 0.044 13.2 0.1 0.044 13.2 0.1 1.9 2 0 0 2 2 2 0 Transmembrane alpha-helix domain TAXi_N PF14543.6 OAP65739.1 - 0.15 12.3 1.1 0.46 10.7 0.0 2.4 3 1 1 4 4 4 0 Xylanase inhibitor N-terminal LapA_dom PF06305.11 OAP65739.1 - 0.22 11.4 0.4 0.43 10.4 0.4 1.5 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Clathrin PF00637.20 OAP65740.1 - 8e-22 77.7 1.3 4.3e-20 72.1 0.4 2.7 2 0 0 2 2 2 1 Region in Clathrin and VPS VPS11_C PF12451.8 OAP65740.1 - 1.3e-18 66.9 0.4 2.7e-18 65.9 0.4 1.6 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal zf-C3H2C3 PF17122.5 OAP65740.1 - 0.00021 21.3 6.7 0.00077 19.5 6.7 2.0 1 1 0 1 1 1 1 Zinc-finger zf-RING_2 PF13639.6 OAP65740.1 - 0.00047 20.4 6.1 0.00092 19.5 6.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 OAP65740.1 - 0.00054 19.7 6.6 0.0012 18.7 6.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAP65740.1 - 0.00073 19.4 5.7 0.0014 18.6 5.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain TPR_11 PF13414.6 OAP65740.1 - 0.00084 19.0 0.3 0.0022 17.6 0.3 1.7 1 0 0 1 1 1 1 TPR repeat zf-RING_UBOX PF13445.6 OAP65740.1 - 0.0023 17.9 4.2 0.0046 17.0 4.2 1.5 1 0 0 1 1 1 1 RING-type zinc-finger TPR_14 PF13428.6 OAP65740.1 - 0.0028 18.3 0.3 0.34 11.8 0.0 4.2 5 0 0 5 5 3 1 Tetratricopeptide repeat zf-HC5HC2H PF13771.6 OAP65740.1 - 0.0065 16.7 1.0 0.015 15.6 1.0 1.5 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-rbx1 PF12678.7 OAP65740.1 - 0.0079 16.5 4.4 0.017 15.4 4.4 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 OAP65740.1 - 0.0093 15.8 7.0 0.018 14.9 7.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 OAP65740.1 - 0.0094 16.0 1.5 0.021 14.9 1.5 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger TPR_12 PF13424.6 OAP65740.1 - 0.012 15.9 0.9 0.25 11.7 0.3 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat eIF3_N PF09440.10 OAP65740.1 - 0.033 14.6 1.5 0.085 13.3 0.8 2.1 2 0 0 2 2 1 0 eIF3 subunit 6 N terminal domain TPR_2 PF07719.17 OAP65740.1 - 0.053 13.7 1.8 0.2 11.8 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF4810 PF16068.5 OAP65740.1 - 0.089 13.3 0.1 15 6.2 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4810) zf-HC5HC2H_2 PF13832.6 OAP65740.1 - 0.09 13.0 0.9 0.22 11.7 0.9 1.7 1 0 0 1 1 1 0 PHD-zinc-finger like domain TPR_8 PF13181.6 OAP65740.1 - 0.23 11.8 1.0 1.7 9.1 0.3 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat PHD PF00628.29 OAP65740.1 - 0.67 9.9 4.1 1.4 8.8 4.1 1.6 1 0 0 1 1 1 0 PHD-finger zf-RING_11 PF17123.5 OAP65740.1 - 1.6 8.5 4.8 4.1 7.2 4.8 1.7 1 0 0 1 1 1 0 RING-like zinc finger zf-C3HC4_4 PF15227.6 OAP65740.1 - 2.8 8.2 5.4 5.5 7.2 5.4 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING TPR_1 PF00515.28 OAP65740.1 - 5.7 6.9 5.7 3.3 7.7 0.3 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Pkinase PF00069.25 OAP65741.1 - 7.9e-59 199.2 0.0 2.1e-58 197.8 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAP65741.1 - 2.8e-35 121.8 0.0 4.9e-35 121.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.16 OAP65741.1 - 9.7e-29 99.3 16.8 2.3e-14 53.3 4.1 2.9 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.22 OAP65741.1 - 4.8e-20 71.2 28.6 5.4e-12 45.4 9.9 2.4 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.24 OAP65741.1 - 5.1e-14 52.7 0.8 2e-13 50.8 0.8 2.2 1 0 0 1 1 1 1 Protein kinase C terminal domain C2 PF00168.30 OAP65741.1 - 2.3e-05 24.6 0.1 4.3e-05 23.7 0.1 1.4 1 0 0 1 1 1 1 C2 domain Sugar_tr PF00083.24 OAP65742.1 - 6.7e-90 302.1 23.3 7.9e-90 301.9 23.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAP65742.1 - 1.2e-28 100.1 40.5 2.5e-18 66.1 24.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3792 PF12670.7 OAP65742.1 - 8.5 6.6 18.8 7.2 6.8 5.5 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3792) Glyco_hydro_2_C PF02836.17 OAP65743.1 - 1.1e-106 356.3 0.0 1.5e-106 356.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.17 OAP65743.1 - 2.5e-60 204.1 0.0 3.9e-60 203.5 0.0 1.3 1 0 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.18 OAP65743.1 - 3.2e-44 150.8 0.2 8.6e-44 149.4 0.1 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain DUF4981 PF16353.5 OAP65743.1 - 6.8e-18 64.9 0.2 1.1e-16 61.1 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function(DUF4981) Glyco_hydro_2 PF00703.21 OAP65743.1 - 7.3e-15 55.6 0.0 1.4e-14 54.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.6 OAP65743.1 - 0.00055 20.5 0.0 0.0016 19.0 0.0 1.8 1 0 0 1 1 1 1 Beta-galactosidase jelly roll domain Fungal_trans PF04082.18 OAP65744.1 - 0.0002 20.5 0.0 0.00041 19.5 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF2633 PF11119.8 OAP65744.1 - 0.063 13.2 1.0 0.12 12.3 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) Aldo_ket_red PF00248.21 OAP65745.1 - 2.6e-63 214.0 0.0 3.2e-63 213.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Cupin_2 PF07883.11 OAP65746.1 - 1.3e-11 44.1 0.0 2e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 OAP65746.1 - 0.0011 18.7 0.1 0.0018 17.9 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_1 PF00190.22 OAP65746.1 - 0.0031 17.1 0.0 0.0056 16.3 0.0 1.4 1 0 0 1 1 1 1 Cupin Cupin_6 PF12852.7 OAP65746.1 - 0.011 15.5 0.0 0.015 15.0 0.0 1.2 1 0 0 1 1 1 0 Cupin F-box-like PF12937.7 OAP65747.1 - 0.00015 21.5 0.2 0.00036 20.4 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAP65747.1 - 0.023 14.6 0.7 0.048 13.6 0.7 1.6 1 0 0 1 1 1 0 F-box domain Sulfatase PF00884.23 OAP65748.1 - 2.1e-63 214.6 0.0 2.7e-63 214.2 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 OAP65748.1 - 0.0027 17.4 0.0 0.0048 16.5 0.0 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 OAP65748.1 - 0.0044 15.7 0.0 0.0069 15.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) DUF4994 PF16385.5 OAP65748.1 - 0.021 14.7 0.0 0.045 13.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function NACHT PF05729.12 OAP65750.1 - 2.8e-08 33.9 0.1 6.3e-08 32.7 0.1 1.7 1 0 0 1 1 1 1 NACHT domain SesA PF17107.5 OAP65750.1 - 6.5e-06 26.3 2.2 1.2e-05 25.5 0.2 2.7 3 0 0 3 3 3 1 N-terminal domain on NACHT_NTPase and P-loop NTPases AAA_16 PF13191.6 OAP65750.1 - 1.8e-05 25.2 2.3 3.2e-05 24.4 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 OAP65750.1 - 3e-05 24.3 0.6 0.00017 21.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 OAP65750.1 - 0.0013 18.7 0.0 0.0031 17.5 0.0 1.5 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea NB-ARC PF00931.22 OAP65750.1 - 0.002 17.4 0.3 0.0078 15.4 0.0 2.0 2 0 0 2 2 2 1 NB-ARC domain ABC_tran PF00005.27 OAP65750.1 - 0.0094 16.5 0.0 0.026 15.1 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_30 PF13604.6 OAP65750.1 - 0.024 14.3 0.0 0.063 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 OAP65750.1 - 0.027 14.2 0.0 0.12 12.1 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain RNA_helicase PF00910.22 OAP65750.1 - 0.2 12.0 0.0 0.59 10.6 0.0 1.8 1 0 0 1 1 1 0 RNA helicase DUF4410 PF14366.6 OAP65751.1 - 0.043 13.7 0.4 0.097 12.6 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4410) DUF3500 PF12006.8 OAP65752.1 - 2.1e-109 365.6 0.0 2.6e-109 365.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3500) DUF4185 PF13810.6 OAP65753.1 - 1.7e-16 60.4 4.8 7e-16 58.3 2.6 2.0 2 0 0 2 2 2 2 Domain of unknown function (DUF4185) MFS_1 PF07690.16 OAP65754.1 - 1.3e-20 73.7 45.7 3.8e-15 55.7 32.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily eIF-1a PF01176.19 OAP65755.1 - 1.3e-16 60.1 0.0 2e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 CSD2 PF17876.1 OAP65755.1 - 0.12 12.5 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 Cold shock domain ALG3 PF05208.13 OAP65756.1 - 5.2e-131 437.3 8.8 6e-131 437.1 8.8 1.0 1 0 0 1 1 1 1 ALG3 protein FMN_dh PF01070.18 OAP65757.1 - 1.1e-126 422.6 0.0 1.3e-126 422.3 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 OAP65757.1 - 1.2e-07 31.1 0.2 3e-07 29.8 0.2 1.6 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 OAP65757.1 - 8.7e-06 25.1 0.0 1.9e-05 24.0 0.0 1.6 1 1 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.15 OAP65757.1 - 5.7e-05 22.7 0.8 8.7e-05 22.1 0.8 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.21 OAP65757.1 - 0.00037 20.0 0.0 0.0014 18.1 0.0 1.9 1 1 1 2 2 2 1 Histidine biosynthesis protein ThiG PF05690.14 OAP65757.1 - 0.0074 15.6 0.4 0.27 10.5 0.0 2.2 2 0 0 2 2 2 1 Thiazole biosynthesis protein ThiG zf-C2H2_4 PF13894.6 OAP65758.1 - 6.7e-08 32.7 25.1 0.051 14.4 1.2 6.1 6 0 0 6 6 6 4 C2H2-type zinc finger zf-C2H2 PF00096.26 OAP65758.1 - 3.3e-07 30.4 30.0 0.1 13.1 0.5 6.0 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 OAP65758.1 - 6.3e-07 29.5 17.7 0.11 12.8 0.2 5.6 6 0 0 6 6 6 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OAP65758.1 - 0.026 14.9 24.7 1.6 9.2 0.1 5.7 6 0 0 6 6 6 0 Zinc-finger of C2H2 type zf-C2H2_9 PF16293.5 OAP65758.1 - 0.064 13.1 13.2 1.2 9.1 0.8 4.1 2 2 2 4 4 4 0 C2H2 type zinc-finger (1 copy) zf-C2H2_6 PF13912.6 OAP65758.1 - 0.11 12.5 16.1 2.3 8.3 0.2 5.0 4 1 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 OAP65758.1 - 0.58 10.3 0.1 0.58 10.3 0.1 3.9 2 2 1 3 3 3 0 Aberrant zinc-finger zf-C2H2_2 PF12756.7 OAP65758.1 - 5.4 7.4 27.1 18 5.7 0.1 4.5 2 2 2 4 4 4 0 C2H2 type zinc-finger (2 copies) Zn_Tnp_IS1595 PF12760.7 OAP65758.1 - 5.5 7.1 15.0 0.72 9.9 2.0 4.0 4 0 0 4 4 4 0 Transposase zinc-ribbon domain zf-C2HE PF16278.5 OAP65758.1 - 9.5 6.8 7.0 9 6.8 0.1 3.0 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger PLDc_2 PF13091.6 OAP65759.1 - 3.7e-16 59.2 0.0 4.4e-06 26.6 0.0 4.0 3 1 0 3 3 3 3 PLD-like domain PLDc PF00614.22 OAP65759.1 - 7.8e-14 51.2 1.2 1.3e-05 25.2 0.2 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif Cyanate_lyase PF02560.14 OAP65760.1 - 8.8e-31 105.6 0.0 1.4e-30 105.0 0.0 1.3 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain HTH_3 PF01381.22 OAP65760.1 - 0.0033 17.5 0.0 0.0051 16.8 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix Hid1 PF12722.7 OAP65762.1 - 1.7 6.6 5.4 1.9 6.5 5.4 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RRM_1 PF00076.22 OAP65763.1 - 4.7e-21 74.4 0.0 2.9e-12 46.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Colicin_Ia PF11504.8 OAP65763.1 - 0.14 12.3 1.5 2.3 8.4 0.0 2.5 2 0 0 2 2 2 0 Colicin Ia RRM_7 PF16367.5 OAP65763.1 - 0.15 12.2 0.0 5.4 7.2 0.0 2.7 2 1 0 2 2 2 0 RNA recognition motif AAA PF00004.29 OAP65764.1 - 2.4e-07 31.2 0.2 1.7e-06 28.5 0.2 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OAP65764.1 - 0.00022 21.5 0.1 0.0013 19.0 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_7 PF12775.7 OAP65764.1 - 0.0013 18.3 0.4 0.89 9.0 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_16 PF13191.6 OAP65764.1 - 0.0018 18.7 0.1 0.0057 17.1 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_11 PF13086.6 OAP65764.1 - 0.0031 17.3 0.4 0.018 14.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 OAP65764.1 - 0.0039 17.2 0.0 0.054 13.4 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain TIP49 PF06068.13 OAP65764.1 - 0.01 15.0 0.0 0.018 14.2 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_18 PF13238.6 OAP65764.1 - 0.016 15.8 0.0 0.056 14.0 0.0 2.1 1 1 0 1 1 1 0 AAA domain RuvB_N PF05496.12 OAP65764.1 - 0.029 14.1 0.0 0.056 13.2 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain NTPase_1 PF03266.15 OAP65764.1 - 0.031 14.2 0.0 0.069 13.1 0.0 1.6 1 0 0 1 1 1 0 NTPase T2SSE PF00437.20 OAP65764.1 - 0.032 13.3 0.0 0.06 12.4 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_28 PF13521.6 OAP65764.1 - 0.051 13.8 0.0 0.15 12.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 OAP65764.1 - 0.072 12.8 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 OAP65764.1 - 0.087 12.8 0.0 0.28 11.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 OAP65764.1 - 0.11 12.8 0.0 0.3 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 OAP65764.1 - 0.11 12.6 0.1 0.86 9.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain PurS PF02700.14 OAP65764.1 - 0.18 12.0 0.0 0.43 10.8 0.0 1.6 1 0 0 1 1 1 0 Phosphoribosylformylglycinamidine (FGAM) synthase Utp8 PF10395.9 OAP65765.1 - 1.9e-09 36.6 0.0 2.1e-08 33.2 0.0 2.5 2 1 0 2 2 2 1 Utp8 family DUF4375 PF14300.6 OAP65765.1 - 0.22 11.8 0.0 2.1 8.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4375) SAM_2 PF07647.17 OAP65766.1 - 6.6e-17 61.4 0.0 1e-16 60.8 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 OAP65766.1 - 1.4e-13 51.0 0.0 2.4e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.23 OAP65766.1 - 1.5e-08 35.2 0.0 3.5e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SAM_4 PF18017.1 OAP65766.1 - 0.06 13.3 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) EnY2 PF10163.9 OAP65767.1 - 1.1e-06 28.9 0.1 2.2e-06 28.0 0.0 1.5 2 0 0 2 2 2 1 Transcription factor e(y)2 AAA PF00004.29 OAP65768.1 - 1.6e-96 319.8 0.1 1e-46 158.7 0.0 2.8 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OAP65768.1 - 7.1e-25 86.6 4.3 9.9e-13 47.7 0.7 3.1 2 1 0 2 2 2 2 AAA+ lid domain CDC48_N PF02359.18 OAP65768.1 - 4.9e-19 68.3 0.4 1.4e-18 66.8 0.4 1.9 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_2 PF07724.14 OAP65768.1 - 3.4e-14 53.3 0.0 1e-07 32.2 0.0 3.1 3 1 0 3 3 2 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 OAP65768.1 - 7.3e-14 51.8 0.0 1.4e-05 24.9 0.0 3.0 2 2 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 OAP65768.1 - 4.2e-13 49.7 0.0 1.8e-05 25.0 0.0 3.3 3 0 0 3 3 2 2 AAA domain AAA_16 PF13191.6 OAP65768.1 - 1.5e-11 44.9 0.0 0.00026 21.4 0.0 4.7 3 2 1 4 4 3 2 AAA ATPase domain AAA_5 PF07728.14 OAP65768.1 - 1.9e-11 44.1 0.4 3e-05 24.0 0.1 3.8 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 OAP65768.1 - 2e-09 37.9 0.4 0.025 14.8 0.0 4.5 2 2 1 3 3 3 2 AAA domain TIP49 PF06068.13 OAP65768.1 - 3.5e-09 36.3 0.0 0.0015 17.8 0.0 2.8 2 0 0 2 2 2 2 TIP49 P-loop domain CDC48_2 PF02933.17 OAP65768.1 - 5.7e-08 32.4 0.0 1.3e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 Mg_chelatase PF01078.21 OAP65768.1 - 9.6e-08 31.6 0.4 0.0069 15.8 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 OAP65768.1 - 3.1e-07 30.3 0.0 0.019 14.7 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.6 OAP65768.1 - 6.2e-07 30.0 0.0 0.029 14.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain Vps4_C PF09336.10 OAP65768.1 - 1.2e-06 28.4 0.1 1.4e-05 25.0 0.0 2.5 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_14 PF13173.6 OAP65768.1 - 1.7e-06 28.1 0.0 0.022 14.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 OAP65768.1 - 1.8e-06 28.3 0.0 0.029 14.7 0.0 2.9 2 0 0 2 2 2 2 RNA helicase AAA_25 PF13481.6 OAP65768.1 - 2.4e-06 27.3 4.7 0.2 11.2 0.1 4.6 3 2 2 5 5 5 2 AAA domain ATPase PF06745.13 OAP65768.1 - 2.5e-06 27.0 0.4 0.86 8.9 0.0 3.6 3 0 0 3 3 3 2 KaiC AAA_28 PF13521.6 OAP65768.1 - 5.7e-06 26.7 0.1 0.18 12.0 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_7 PF12775.7 OAP65768.1 - 6.1e-06 25.9 0.1 0.032 13.7 0.0 3.0 2 2 0 2 2 2 2 P-loop containing dynein motor region AAA_24 PF13479.6 OAP65768.1 - 3.5e-05 23.6 0.0 0.31 10.7 0.0 2.9 3 0 0 3 3 2 2 AAA domain ABC_tran PF00005.27 OAP65768.1 - 4.6e-05 23.9 0.0 0.27 11.7 0.0 3.5 2 1 0 2 2 2 1 ABC transporter DUF815 PF05673.13 OAP65768.1 - 5.3e-05 22.5 0.0 0.019 14.1 0.0 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Sigma54_activat PF00158.26 OAP65768.1 - 5.5e-05 22.9 0.1 0.61 9.8 0.0 3.3 2 2 0 2 2 2 2 Sigma-54 interaction domain Parvo_NS1 PF01057.17 OAP65768.1 - 5.6e-05 22.4 0.1 0.052 12.6 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Bac_DnaA PF00308.18 OAP65768.1 - 9.2e-05 22.4 0.0 0.38 10.6 0.0 2.9 3 0 0 3 3 2 2 Bacterial dnaA protein AAA_17 PF13207.6 OAP65768.1 - 0.00014 22.3 0.4 0.89 10.0 0.0 3.7 3 1 0 3 3 3 1 AAA domain PhoH PF02562.16 OAP65768.1 - 0.00016 21.2 0.4 0.68 9.3 0.1 2.5 2 0 0 2 2 2 2 PhoH-like protein ResIII PF04851.15 OAP65768.1 - 0.00042 20.4 0.0 0.11 12.5 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit TsaE PF02367.17 OAP65768.1 - 0.00047 20.2 0.0 0.51 10.4 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_3 PF07726.11 OAP65768.1 - 0.00057 19.7 0.0 1.6 8.6 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 OAP65768.1 - 0.00065 19.6 0.1 0.76 9.5 0.0 2.7 2 1 0 2 2 2 2 AAA domain NACHT PF05729.12 OAP65768.1 - 0.0008 19.4 0.1 0.18 11.7 0.0 2.9 3 0 0 3 3 3 1 NACHT domain AAA_30 PF13604.6 OAP65768.1 - 0.0016 18.2 0.4 1.1 8.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 OAP65768.1 - 0.0028 17.4 0.0 0.35 10.6 0.0 2.7 3 0 0 3 3 2 1 Viral (Superfamily 1) RNA helicase ATPase_2 PF01637.18 OAP65768.1 - 0.0034 17.3 0.0 6.8 6.5 0.0 3.5 3 1 1 4 4 4 0 ATPase domain predominantly from Archaea DUF2075 PF09848.9 OAP65768.1 - 0.0047 16.2 0.0 2.2 7.4 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 OAP65768.1 - 0.0055 17.0 1.0 5.8 7.2 0.0 3.5 3 1 0 4 4 2 0 AAA domain UFD1 PF03152.14 OAP65768.1 - 0.0087 15.5 0.0 0.074 12.5 0.0 2.0 1 1 1 2 2 2 1 Ubiquitin fusion degradation protein UFD1 Zeta_toxin PF06414.12 OAP65768.1 - 0.011 15.0 0.4 6.3 6.0 0.0 2.9 3 0 0 3 3 2 0 Zeta toxin NTPase_1 PF03266.15 OAP65768.1 - 0.011 15.6 1.0 2.5 8.0 0.0 3.9 4 0 0 4 4 3 0 NTPase KAP_NTPase PF07693.14 OAP65768.1 - 0.013 14.8 0.0 0.72 9.0 0.0 2.7 2 1 0 3 3 3 0 KAP family P-loop domain IPT PF01745.16 OAP65768.1 - 0.016 14.6 0.0 2.3 7.5 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase NB-ARC PF00931.22 OAP65768.1 - 0.021 14.0 0.0 1.4 8.0 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain Sigma54_activ_2 PF14532.6 OAP65768.1 - 0.023 14.8 0.0 3.7 7.7 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_6 PF12774.7 OAP65768.1 - 0.074 12.0 0.3 11 4.9 0.0 2.5 3 0 0 3 3 2 0 Hydrolytic ATP binding site of dynein motor region Cytidylate_kin PF02224.18 OAP65768.1 - 0.075 12.8 0.0 10 5.8 0.0 2.7 2 0 0 2 2 2 0 Cytidylate kinase AFG1_ATPase PF03969.16 OAP65768.1 - 0.13 11.1 0.0 13 4.5 0.0 2.3 2 0 0 2 2 2 0 AFG1-like ATPase Zot PF05707.12 OAP65768.1 - 0.18 11.4 0.0 7.1 6.2 0.0 2.9 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) eIF-1a PF01176.19 OAP65768.1 - 0.26 11.1 1.1 1.7 8.5 0.4 2.5 1 1 1 2 2 2 0 Translation initiation factor 1A / IF-1 Kei1 PF08552.11 OAP65769.1 - 8.5e-65 218.2 2.9 1.1e-64 217.9 2.9 1.1 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 ADH_N PF08240.12 OAP65770.1 - 1.9e-26 92.1 0.3 1.2e-25 89.5 0.0 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAP65770.1 - 4.9e-20 71.8 0.0 9e-20 71.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 OAP65770.1 - 8.5e-08 31.9 0.2 6.8e-07 29.0 0.2 2.2 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 OAP65770.1 - 1.9e-05 25.7 0.0 5.7e-05 24.2 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 OAP65770.1 - 0.028 13.7 0.1 0.048 12.9 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 OAP65770.1 - 0.1 11.8 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAP65770.1 - 0.12 13.0 0.1 0.27 11.8 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_2 PF00891.18 OAP65770.1 - 0.17 11.2 0.1 0.3 10.4 0.1 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Pantoate_transf PF02548.15 OAP65771.1 - 8.8e-85 284.2 1.1 1.1e-84 283.9 1.1 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 OAP65771.1 - 8.1e-05 22.2 1.2 0.0005 19.6 1.2 2.3 1 1 0 1 1 1 1 Phosphoenolpyruvate phosphomutase PAP2_3 PF14378.6 OAP65772.1 - 5.4e-29 101.2 10.2 4.1e-13 49.4 0.1 3.2 3 0 0 3 3 3 3 PAP2 superfamily GHMP_kinases_N PF00288.26 OAP65773.1 - 8.7e-17 61.1 3.7 2.1e-16 59.9 3.7 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 OAP65773.1 - 5.9e-08 33.0 0.0 1.7e-07 31.5 0.0 1.7 2 0 0 2 2 2 1 GHMP kinases C terminal SH3_15 PF18346.1 OAP65773.1 - 0.052 13.9 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 Mind bomb SH3 repeat domain Rad60-SLD_2 PF13881.6 OAP65774.1 - 6.5e-10 39.1 0.0 1.8e-09 37.7 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 OAP65774.1 - 0.012 16.1 0.0 0.023 15.3 0.0 1.5 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain SSP160 PF06933.11 OAP65774.1 - 3 5.9 5.9 3.8 5.6 5.9 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 UMP1 PF05348.11 OAP65775.1 - 5.5e-35 120.1 0.0 7.2e-35 119.8 0.0 1.2 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 PRK PF00485.18 OAP65777.1 - 1.1e-56 191.8 0.0 1.6e-56 191.2 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.6 OAP65777.1 - 1.1e-38 132.8 0.0 1.9e-38 132.0 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AAA_18 PF13238.6 OAP65777.1 - 2.7e-06 28.0 0.0 5.6e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain CPT PF07931.12 OAP65777.1 - 0.00017 21.5 0.0 0.0004 20.3 0.0 1.6 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.6 OAP65777.1 - 0.0014 18.8 0.0 0.007 16.5 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 OAP65777.1 - 0.0042 17.5 0.2 0.084 13.3 0.2 2.5 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 OAP65777.1 - 0.013 14.8 0.0 0.025 13.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA PF00004.29 OAP65777.1 - 0.052 14.0 0.0 0.51 10.8 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Cytidylate_kin PF02224.18 OAP65777.1 - 0.071 12.8 0.1 1.7 8.3 0.0 2.3 1 1 0 2 2 2 0 Cytidylate kinase TIP49 PF06068.13 OAP65777.1 - 0.076 12.2 0.3 0.19 10.9 0.1 1.7 1 1 1 2 2 2 0 TIP49 P-loop domain NB-ARC PF00931.22 OAP65777.1 - 0.083 12.1 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain CbiA PF01656.23 OAP65777.1 - 0.084 12.9 0.1 0.3 11.1 0.1 2.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain MobB PF03205.14 OAP65777.1 - 0.12 12.3 0.1 0.29 11.0 0.1 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B APS_kinase PF01583.20 OAP65777.1 - 0.17 11.8 0.2 4.1 7.3 0.0 2.8 3 0 0 3 3 3 0 Adenylylsulphate kinase ABC_tran PF00005.27 OAP65777.1 - 0.19 12.3 0.3 0.92 10.0 0.1 2.1 2 0 0 2 2 2 0 ABC transporter RNase_T PF00929.24 OAP65778.1 - 2.2e-17 64.1 0.0 4.2e-17 63.2 0.0 1.5 1 0 0 1 1 1 1 Exonuclease RNase_H2_suC PF08615.11 OAP65779.1 - 5.7e-23 81.6 0.0 1.2e-22 80.6 0.0 1.6 1 1 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) DUF4385 PF14328.6 OAP65780.1 - 8.9e-52 175.1 0.2 1.1e-51 174.7 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4385) Auts2 PF15336.6 OAP65782.1 - 0.00045 20.4 1.8 0.00061 20.0 1.8 1.2 1 0 0 1 1 1 1 Autism susceptibility gene 2 protein bZIP_1 PF00170.21 OAP65782.1 - 0.0029 17.7 16.3 0.014 15.5 16.3 2.0 1 1 0 1 1 1 1 bZIP transcription factor ATG16 PF08614.11 OAP65782.1 - 0.0079 16.4 5.1 0.011 16.0 5.1 1.1 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) DUF848 PF05852.11 OAP65782.1 - 0.012 15.7 1.6 0.017 15.2 1.6 1.1 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) bZIP_Maf PF03131.17 OAP65782.1 - 0.021 15.3 8.7 0.036 14.6 8.7 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor UPF0242 PF06785.11 OAP65782.1 - 0.024 14.8 3.8 0.035 14.2 3.8 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TSC22 PF01166.18 OAP65782.1 - 0.03 14.6 1.8 0.056 13.8 1.4 1.6 1 1 0 1 1 1 0 TSC-22/dip/bun family GIT_CC PF16559.5 OAP65782.1 - 0.042 13.7 2.5 0.073 13.0 2.5 1.4 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor Jnk-SapK_ap_N PF09744.9 OAP65782.1 - 0.2 11.9 8.3 0.29 11.4 8.3 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF5094 PF17015.5 OAP65782.1 - 0.23 11.5 2.1 0.32 11.1 2.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5094) Fungal_trans_2 PF11951.8 OAP65783.1 - 4.3e-05 22.5 0.0 8.8e-05 21.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 OAP65784.1 - 4.8e-42 144.2 37.0 4.8e-42 144.2 37.0 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAP65784.1 - 1.1e-10 41.0 8.6 1.1e-10 41.0 8.6 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 OAP65784.1 - 1.3e-07 30.4 1.8 1.3e-07 30.4 1.8 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 OAP65784.1 - 1.1 7.4 7.6 2 6.6 6.0 2.2 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DcpS PF05652.12 OAP65785.1 - 1.4e-33 115.9 0.0 2.2e-33 115.2 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal DcpS_C PF11969.8 OAP65785.1 - 9.9e-26 90.5 0.0 1.5e-25 89.9 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Fonsecaea_erecta-ASM165198v1/GCA_001651985.1_ASM165198v1_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Fonsecaea_erecta-ASM165198v1/GCA_001651985.1_ASM165198v1_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Fonsecaea_erecta-ASM165198v1/GCA_001651985.1_ASM165198v1_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Fonsecaea_erecta-ASM165198v1/GCA_001651985.1_ASM165198v1_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Sun Mar 24 20:49:13 2019 # [ok]